# hmmscan :: search sequence(s) against a profile database
# HMMER 3.2.1 (June 2018); http://hmmer.org/
# Copyright (C) 2018 Howard Hughes Medical Institute.
# Freely distributed under the BSD open source license.
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query sequence file:             /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Talaromyces_marneffei_ATCC_18224-JCVI-PMFA1-2.0/GCA_000001985.1_JCVI-PMFA1-2.0_protein.faa
# target HMM database:             /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm
# output directed to file:         /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Talaromyces_marneffei_ATCC_18224-JCVI-PMFA1-2.0/GCA_000001985.1_JCVI-PMFA1-2.0_protein.PFam32-A
# per-seq hits tabular output:     /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Talaromyces_marneffei_ATCC_18224-JCVI-PMFA1-2.0/GCA_000001985.1_JCVI-PMFA1-2.0_protein.PFam32-A.tblout
# number of worker threads:        20
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       EEA18456.1  [L=1142]
Description: DNA helicase recq, putative, partial [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.9e-12   47.0   9.6    2.9e-12   47.0   9.6    2.4  2  OrsD          Orsellinic acid/F9775 biosynthesis cluster prot
    3.4e-11   43.2   0.0    1.1e-10   41.5   0.0    1.8  1  DEAD          DEAD/DEAH box helicase
    0.00054   20.0   0.0     0.0014   18.7   0.0    1.7  1  ResIII        Type III restriction enzyme, res subunit
  ------ inclusion threshold ------
      0.097   11.9   0.0       0.16   11.2   0.0    1.3  1  Peptidase_S8  Subtilase family
        1.8    8.2   8.7       0.14   11.8   3.0    2.2  2  zf-C2H2_12    Zinc-finger C2H2-type


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.0   9.6   8.2e-16   2.9e-12       1     114 []       8     118 ..       8     118 .. 0.86
   2 ?   -1.5   0.0      0.95   3.4e+03      35      63 ..     504     531 ..     495     545 .. 0.71

  Alignments for each domain:
  == domain 1  score: 47.0 bits;  conditional E-value: 8.2e-16
        OrsD   1 dlfeyneeyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgL..pvyeGyrCrakakCky 97 
                 ++f+y++++r++iC  C++ v  s+l +HLr+  +  +    ++ ++ +  ++  +q+ e  r++ ++ +p+++ +pipgL  p    y+C   ++C++
  EEA18456.1   8 QIFQYDPHHRIVICCLCQHVVFDSQLPSHLRNTRHIRE----RHSQHIILFQQYHQQFPERIRHHRELVIPHKPIAPIPGLipPRDPTYQC-SYPGCHW 101
                 57*****************************5544443....34556665557788999999******************96555699***.78***** PP

        OrsD  98 ltrslktlrkHlqkkhg 114
                 +  +++++++H +++hg
  EEA18456.1 102 IGETIRRIHDHCRQEHG 118
                 **************995 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.95
        OrsD  35 rqlkrektqelletvehemslrqldelar 63 
                  q++r ++ +l+etv h    r +d+l++
  EEA18456.1 504 YQHHRFTMDQLRETV-HGIINRAWDHLTQ 531
                 456666788999999.8888899996644 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.5   0.0   3.2e-14   1.1e-10       3     173 ..     904    1054 ..     902    1058 .. 0.77

  Alignments for each domain:
  == domain 1  score: 41.5 bits;  conditional E-value: 3.2e-14
                  HHHHHHHHHHTTC.EEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTC CS
                  xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD    3 iQaeaiplilggg.dvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngv 98  
                  iQ++ai++++g    vl+ + TG GK+++f++p+    +    +++   ++v+Pt +L +++ +++ + +      ++ + +  +         +++
  EEA18456.1  904 IQKAAIDAVMGSApWVLGVMGTGGGKSMIFMVPAA---W----ERAGTSIVVVPTVSLRQDMQRECAQAGIS----CVPWNSHRPP--------ETA 981 
                  9*********66559********************...4....456689*******************9994....2222222222........456 PP

                  SEEEEEHHHHHHHH.....HCTSSHCTTEEEEEEETHHHHHHT..TTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHH CS
                  xxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   99 divvgtpgrlddll.....stgklnlsqvrflVlDEadrlldq..gfsdfinrilnqlpqitcdgklqrqvivlSATlpkdv 173 
                  +iv+ tp+   +       s +  + +++  +V+DE++++ld+  +f++++  ++  +   t   +    v++l+ATlp  v
  EEA18456.1  982 RIVLVTPESATSKGfrsyiS-RLQERNRLDRIVIDECHTILDSreEFRPKMAGLHVLM---TIGSP----VVLLTATLP-AV 1054
                  78999998888844354432.2223788899***********9888888888877777...44445....********9.44 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   3.9e-07    0.0014      29     147 ..     921    1023 ..     900    1053 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 3.9e-07
                  EEESTTSTHHHHH.HHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--.......-SEEEEEHHHHHHTH...... CS
      ResIII   29 ikmaTGtGKTlva.aklierllkkgkeekflflvprkslleqtleefkkflseaykeigkkvsgdkkkakekdstnkkilvttiqsldadseeeeee 124 
                   +m TG GK+++  + ++++ +        +++vp+ sl + +++e ++   +++      +++ +  +      +++i+++t +s++++   +++ 
  EEA18456.1  921 GVMGTGGGKSMIFmVPAAWERAG-----TSIVVVPTVSLRQDMQRECAQAGISCV-----PWNSHRPPE------TARIVLVTPESATSKG-FRSYI 1000
                  5899******9985677777776.....689********************9875.....677777777......9999999999999988.56999 PP

                  ..HHHTTT-SEEEEETGGGTTS. CS
      ResIII  125 seellrdrfdviiiDEaHrlgak 147 
                  s  ++r+r d i+iDE+H + ++
  EEA18456.1 1001 SRLQERNRLDRIVIDECHTILDS 1023
                  9999**************98875 PP

>> Peptidase_S8  Subtilase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   4.6e-05      0.16      49      88 ..     797     838 ..     708     847 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 4.6e-05
                   S-TT-SC-SSS......HHHHHHHHHH-B..SSSSSB-SSTT CS
                   xxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8  49 tstnwarddngnsie..HGthvAGiaaanapeegekngvapg 88 
                       w++dd + +i+  HG+hvAG++ a   ee      a +
    EEA18456.1 797 DGCWWTADDAVIDIQagHGSHVAGMIYARGVEEAPGTMAAMK 838
                   34447777877777799**********995555555555555 PP

>> zf-C2H2_12  Zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   3.0   3.8e-05      0.14      14      59 ..      10      58 ..       6      64 .. 0.80
   2 ?   -3.8   0.3       2.8     1e+04      37      48 ..     106     117 ..      94     118 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3.8e-05
  zf-C2H2_12 14 mdydpqrrglvCmvCgeslaslkl.stik..rHIrqvHPeslslseeek 59
                  ydp++r ++C  C+++    +l s+++  rHIr++H + + l ++ +
  EEA18456.1 10 FQYDPHHRIVICCLCQHVVFDSQLpSHLRntRHIRERHSQHIILFQQYH 58
                68***************999999844554338******99877766655 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 2.8
  zf-C2H2_12  37 lstikrHIrqvH 48 
                 + +i  H rq H
  EEA18456.1 106 IRRIHDHCRQEH 117
                 678999999999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1142 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       538  (0.0300073); expected 358.6 (0.02)
Passed bias filter:                      389  (0.0216967); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.90u 0.34s 00:00:01.24 Elapsed: 00:00:00.59
# Mc/sec: 5815.84
//
Query:       EEA18457.1  [L=1134]
Description: DNA helicase recq, putative, partial [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.9e-12   47.0   9.6    2.9e-12   47.0   9.6    2.4  2  OrsD          Orsellinic acid/F9775 biosynthesis cluster prot
    3.3e-11   43.2   0.0    1.1e-10   41.5   0.0    1.9  1  DEAD          DEAD/DEAH box helicase
    0.00053   20.0   0.0     0.0014   18.7   0.0    1.7  1  ResIII        Type III restriction enzyme, res subunit
  ------ inclusion threshold ------
      0.097   11.9   0.0       0.16   11.2   0.0    1.3  1  Peptidase_S8  Subtilase family
        1.8    8.2   8.7       0.14   11.8   3.0    2.2  2  zf-C2H2_12    Zinc-finger C2H2-type


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.0   9.6   8.1e-16   2.9e-12       1     114 []       8     118 ..       8     118 .. 0.86
   2 ?   -1.5   0.0      0.95   3.4e+03      35      63 ..     504     531 ..     495     545 .. 0.71

  Alignments for each domain:
  == domain 1  score: 47.0 bits;  conditional E-value: 8.1e-16
        OrsD   1 dlfeyneeyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgL..pvyeGyrCrakakCky 97 
                 ++f+y++++r++iC  C++ v  s+l +HLr+  +  +    ++ ++ +  ++  +q+ e  r++ ++ +p+++ +pipgL  p    y+C   ++C++
  EEA18457.1   8 QIFQYDPHHRIVICCLCQHVVFDSQLPSHLRNTRHIRE----RHSQHIILFQQYHQQFPERIRHHRELVIPHKPIAPIPGLipPRDPTYQC-SYPGCHW 101
                 57*****************************5544443....34556665557788999999******************96555699***.78***** PP

        OrsD  98 ltrslktlrkHlqkkhg 114
                 +  +++++++H +++hg
  EEA18457.1 102 IGETIRRIHDHCRQEHG 118
                 **************995 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.95
        OrsD  35 rqlkrektqelletvehemslrqldelar 63 
                  q++r ++ +l+etv h    r +d+l++
  EEA18457.1 504 YQHHRFTMDQLRETV-HGIINRAWDHLTQ 531
                 456666788999999.8888899996644 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.5   0.0   3.2e-14   1.1e-10       3     173 ..     904    1054 ..     902    1058 .. 0.77

  Alignments for each domain:
  == domain 1  score: 41.5 bits;  conditional E-value: 3.2e-14
                  HHHHHHHHHHTTC.EEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTC CS
                  xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD    3 iQaeaiplilggg.dvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngv 98  
                  iQ++ai++++g    vl+ + TG GK+++f++p+    +    +++   ++v+Pt +L +++ +++ + +      ++ + +  +         +++
  EEA18457.1  904 IQKAAIDAVMGSApWVLGVMGTGGGKSMIFMVPAA---W----ERAGTSIVVVPTVSLRQDMQRECAQAGIS----CVPWNSHRPP--------ETA 981 
                  9*********66559********************...4....456689*******************9994....2222222222........456 PP

                  SEEEEEHHHHHHHH.....HCTSSHCTTEEEEEEETHHHHHHT..TTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHH CS
                  xxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   99 divvgtpgrlddll.....stgklnlsqvrflVlDEadrlldq..gfsdfinrilnqlpqitcdgklqrqvivlSATlpkdv 173 
                  +iv+ tp+   +       s +  + +++  +V+DE++++ld+  +f++++  ++  +   t   +    v++l+ATlp  v
  EEA18457.1  982 RIVLVTPESATSKGfrsyiS-RLQERNRLDRIVIDECHTILDSreEFRPKMAGLHVLM---TIGSP----VVLLTATLP-AV 1054
                  78999998888844354432.2223788899***********9888888888877777...44445....********9.44 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   3.8e-07    0.0014      29     147 ..     921    1023 ..     900    1053 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 3.8e-07
                  EEESTTSTHHHHH.HHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--.......-SEEEEEHHHHHHTH...... CS
      ResIII   29 ikmaTGtGKTlva.aklierllkkgkeekflflvprkslleqtleefkkflseaykeigkkvsgdkkkakekdstnkkilvttiqsldadseeeeee 124 
                   +m TG GK+++  + ++++ +        +++vp+ sl + +++e ++   +++      +++ +  +      +++i+++t +s++++   +++ 
  EEA18457.1  921 GVMGTGGGKSMIFmVPAAWERAG-----TSIVVVPTVSLRQDMQRECAQAGISCV-----PWNSHRPPE------TARIVLVTPESATSKG-FRSYI 1000
                  5899******9985677777776.....689********************9875.....677777777......9999999999999988.56999 PP

                  ..HHHTTT-SEEEEETGGGTTS. CS
      ResIII  125 seellrdrfdviiiDEaHrlgak 147 
                  s  ++r+r d i+iDE+H + ++
  EEA18457.1 1001 SRLQERNRLDRIVIDECHTILDS 1023
                  9999**************98875 PP

>> Peptidase_S8  Subtilase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   4.6e-05      0.16      49      88 ..     797     838 ..     708     847 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 4.6e-05
                   S-TT-SC-SSS......HHHHHHHHHH-B..SSSSSB-SSTT CS
                   xxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8  49 tstnwarddngnsie..HGthvAGiaaanapeegekngvapg 88 
                       w++dd + +i+  HG+hvAG++ a   ee      a +
    EEA18457.1 797 DGCWWTADDAVIDIQagHGSHVAGMIYARGVEEAPGTMAAMK 838
                   34447777877777799**********995555555555555 PP

>> zf-C2H2_12  Zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   3.0   3.8e-05      0.14      14      59 ..      10      58 ..       6      64 .. 0.80
   2 ?   -3.8   0.3       2.8     1e+04      37      48 ..     106     117 ..      94     118 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3.8e-05
  zf-C2H2_12 14 mdydpqrrglvCmvCgeslaslkl.stik..rHIrqvHPeslslseeek 59
                  ydp++r ++C  C+++    +l s+++  rHIr++H + + l ++ +
  EEA18457.1 10 FQYDPHHRIVICCLCQHVVFDSQLpSHLRntRHIRERHSQHIILFQQYH 58
                68***************999999844554338******99877766655 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 2.8
  zf-C2H2_12  37 lstikrHIrqvH 48 
                 + +i  H rq H
  EEA18457.1 106 IRRIHDHCRQEH 117
                 678999999999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1134 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       535  (0.0298399); expected 358.6 (0.02)
Passed bias filter:                      383  (0.021362); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.94u 0.38s 00:00:01.31 Elapsed: 00:00:00.60
# Mc/sec: 5718.11
//
Query:       EEA18458.1  [L=1124]
Description: DNA helicase recq, putative, partial [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.8e-12   47.1  12.4    2.9e-12   47.0   9.6    2.5  2  OrsD          Orsellinic acid/F9775 biosynthesis cluster prot
    3.4e-11   43.2   0.0    1.1e-10   41.5   0.0    1.8  1  DEAD          DEAD/DEAH box helicase
    0.00053   20.0   0.0     0.0014   18.7   0.0    1.7  1  ResIII        Type III restriction enzyme, res subunit
  ------ inclusion threshold ------
      0.094   12.0   0.0       0.16   11.2   0.0    1.3  1  Peptidase_S8  Subtilase family
        1.7    8.2   8.7       0.14   11.8   3.0    2.2  2  zf-C2H2_12    Zinc-finger C2H2-type


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.0   9.6     8e-16   2.9e-12       1     114 []       8     118 ..       8     118 .. 0.86
   2 ?   -1.5   0.0      0.94   3.4e+03      35      63 ..     486     513 ..     477     527 .. 0.71

  Alignments for each domain:
  == domain 1  score: 47.0 bits;  conditional E-value: 8e-16
        OrsD   1 dlfeyneeyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgL..pvyeGyrCrakakCky 97 
                 ++f+y++++r++iC  C++ v  s+l +HLr+  +  +    ++ ++ +  ++  +q+ e  r++ ++ +p+++ +pipgL  p    y+C   ++C++
  EEA18458.1   8 QIFQYDPHHRIVICCLCQHVVFDSQLPSHLRNTRHIRE----RHSQHIILFQQYHQQFPERIRHHRELVIPHKPIAPIPGLipPRDPTYQC-SYPGCHW 101
                 57*****************************5544443....34556665557788999999******************96555699***.78***** PP

        OrsD  98 ltrslktlrkHlqkkhg 114
                 +  +++++++H +++hg
  EEA18458.1 102 IGETIRRIHDHCRQEHG 118
                 **************995 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.94
        OrsD  35 rqlkrektqelletvehemslrqldelar 63 
                  q++r ++ +l+etv h    r +d+l++
  EEA18458.1 486 YQHHRFTMDQLRETV-HGIINRAWDHLTQ 513
                 456666788999999.8888899996644 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.5   0.0   3.1e-14   1.1e-10       3     173 ..     886    1036 ..     884    1040 .. 0.77

  Alignments for each domain:
  == domain 1  score: 41.5 bits;  conditional E-value: 3.1e-14
                  HHHHHHHHHHTTC.EEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTC CS
                  xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD    3 iQaeaiplilggg.dvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngv 98  
                  iQ++ai++++g    vl+ + TG GK+++f++p+    +    +++   ++v+Pt +L +++ +++ + +      ++ + +  +         +++
  EEA18458.1  886 IQKAAIDAVMGSApWVLGVMGTGGGKSMIFMVPAA---W----ERAGTSIVVVPTVSLRQDMQRECAQAGIS----CVPWNSHRPP--------ETA 963 
                  9*********66559********************...4....456689*******************9994....2222222222........456 PP

                  SEEEEEHHHHHHHH.....HCTSSHCTTEEEEEEETHHHHHHT..TTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHH CS
                  xxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   99 divvgtpgrlddll.....stgklnlsqvrflVlDEadrlldq..gfsdfinrilnqlpqitcdgklqrqvivlSATlpkdv 173 
                  +iv+ tp+   +       s +  + +++  +V+DE++++ld+  +f++++  ++  +   t   +    v++l+ATlp  v
  EEA18458.1  964 RIVLVTPESATSKGfrsyiS-RLQERNRLDRIVIDECHTILDSreEFRPKMAGLHVLM---TIGSP----VVLLTATLP-AV 1036
                  78999998888844354432.2223788899***********9888888888877777...44445....********9.44 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   3.8e-07    0.0014      29     147 ..     903    1005 ..     882    1035 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 3.8e-07
                  EEESTTSTHHHHH.HHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--.......-SEEEEEHHHHHHTH...... CS
      ResIII   29 ikmaTGtGKTlva.aklierllkkgkeekflflvprkslleqtleefkkflseaykeigkkvsgdkkkakekdstnkkilvttiqsldadseeeeee 124 
                   +m TG GK+++  + ++++ +        +++vp+ sl + +++e ++   +++      +++ +  +      +++i+++t +s++++   +++ 
  EEA18458.1  903 GVMGTGGGKSMIFmVPAAWERAG-----TSIVVVPTVSLRQDMQRECAQAGISCV-----PWNSHRPPE------TARIVLVTPESATSKG-FRSYI 982 
                  5899******9985677777776.....689********************9875.....677777777......9999999999999988.56999 PP

                  ..HHHTTT-SEEEEETGGGTTS. CS
      ResIII  125 seellrdrfdviiiDEaHrlgak 147 
                  s  ++r+r d i+iDE+H + ++
  EEA18458.1  983 SRLQERNRLDRIVIDECHTILDS 1005
                  9999**************98875 PP

>> Peptidase_S8  Subtilase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   4.5e-05      0.16      49      88 ..     779     820 ..     690     829 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 4.5e-05
                   S-TT-SC-SSS......HHHHHHHHHH-B..SSSSSB-SSTT CS
                   xxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8  49 tstnwarddngnsie..HGthvAGiaaanapeegekngvapg 88 
                       w++dd + +i+  HG+hvAG++ a   ee      a +
    EEA18458.1 779 DGCWWTADDAVIDIQagHGSHVAGMIYARGVEEAPGTMAAMK 820
                   34447777877777799**********995555555555555 PP

>> zf-C2H2_12  Zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   3.0   3.8e-05      0.14      14      59 ..      10      58 ..       6      64 .. 0.80
   2 ?   -3.8   0.3       2.8   9.9e+03      37      48 ..     106     117 ..      94     118 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3.8e-05
  zf-C2H2_12 14 mdydpqrrglvCmvCgeslaslkl.stik..rHIrqvHPeslslseeek 59
                  ydp++r ++C  C+++    +l s+++  rHIr++H + + l ++ +
  EEA18458.1 10 FQYDPHHRIVICCLCQHVVFDSQLpSHLRntRHIRERHSQHIILFQQYH 58
                68***************999999844554338******99877766655 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 2.8
  zf-C2H2_12  37 lstikrHIrqvH 48 
                 + +i  H rq H
  EEA18458.1 106 IRRIHDHCRQEH 117
                 678999999999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1124 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       515  (0.0287244); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.96u 0.38s 00:00:01.34 Elapsed: 00:00:00.61
# Mc/sec: 5515.01
//
Query:       EEA18459.1  [L=392]
Description: aspergillopepsin F precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.6e-40  138.8   0.2      3e-40  138.6   0.2    1.0  1  Asp       Eukaryotic aspartyl protease
    1.5e-05   25.3   0.0     0.0058   16.9   0.0    3.0  3  TAXi_N    Xylanase inhibitor N-terminal
  ------ inclusion threshold ------
       0.16   11.0   0.0       0.24   10.5   0.0    1.2  1  Dus       Dihydrouridine synthase (Dus)


Domain annotation for each model (and alignments):
>> Asp  Eukaryotic aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.6   0.2     5e-44     3e-40       2     313 ..      83     386 ..      82     388 .. 0.85

  Alignments for each domain:
  == domain 1  score: 138.6 bits;  conditional E-value: 5e-44
                 EEEEEEETTTTEEEEEEEETT--SEEEEBTTESTSHCHHTSS-B-GGG-TT-EEEEEEEEEECTTS.EEEEEEEEEEEEETTEEEEEEEEEEEE..EES CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx..xxx RF
         Asp   2 YfgeisiGtpeqkftvifDTGSsdlWVpsskckkssackshstydpskSstykkngkslsisYGdg.svsGflsqdtvkvggltvknqefgeat..kep 97 
                 Y+++i++G     + v+fDT  sdlWV  + +     +   ++y++++ +      ++++++Y d   + G +++d v vg++   +q+++     ++p
  EEA18459.1  83 YLSPIKVGRD--MLLVTFDTSTSDLWVKTKFSP----SAGTRVYNQTSGTL--LPFHHWQVRYPDTsILGGDVYKDVVRVGQVASFEQAVETLLylHTP 173
                 8999999987..89*************887766....57788998765554..57899********66779******************9987511566 PP

                 SHHHTTSSSSEEEE-S-GGGSCGG...SCCHHHHHHHTTSSSSSEEEEEE-STTSSEEEEEESSEEGGGEEEEEEEEEESS.TSSTEEEEEEEEETTEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxx RF
         Asp  98 gstflaakfdGiLGlgfkeisvee...atpvfdnlvsqglikepvfsvylnreeeeggeivfGgvDeskykGsltyvpvts.kgywqielesvtvggkt 192
                 +s+f ++ +dG+LGl+f+++++++   + +++dn++   ++++pvf+  l   +++ g   fG + +++    ++y  v+s +gyw+i+ +++ +g  +
  EEA18459.1 174 SSVFREV-VDGVLGLAFSSLNTVQpikQRTFYDNVK--PMLSNPVFAACLK--HNTPGFFDFGFIYHARHMTRIYYKLVDSsQGYWNITCDGFMIGRAA 267
                 6666666.9**************9987888899965..57**********5..99************************9889**************99 PP

                 EEEEEEEEEEEETTCSSEEEEHHHHHHHHHHH.TTEEEETTCEEEEETTGGGGSEEEEEEETTEEEEEEGGGGEEEESSSTTSEEEESEEECCTSSSEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp 193 vlcssgcqailDtGTsllalptsivekiakai.gakksesegeyvvdCdslsslpdisftiggakitvpvselvlkeeeseesqCilglvseeegdlwi 290
                 +   + ++a++DtG sll l +si++++  +i +a++s+++  +v++C++    p++s+ ++  + t+p + + + + + + + C+ gl+ ++++d  +
  EEA18459.1 268 S--FNPFHAVVDTGSSLLLLRQSIIAQYYGNItSAYYSQEHAGWVFNCND--VIPSFSIILDLYNATIPGDYIKYVQLN-G-TLCYGGLQVSPSNDFGV 360
                 9..999*******************99987662677888899*******8..778888888888888887655544443.4.69*************** PP

                 EEHHHHTTEEEEEET...TTTEEEEE CS
                 xxxxxxxxxxxxxxx...xxxxxxxx RF
         Asp 291 LGdvFlrsayvvfdl...dnnrvglA 313
                 LG vFl+  yv+fd    +  rvg++
  EEA18459.1 361 LGAVFLKTQYVIFDSrpgKHPRVGFS 386
                 **************722245677776 PP

>> TAXi_N  Xylanase inhibitor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0     0.058   3.5e+02       1      31 [.      83     111 ..      83     132 .. 0.77
   2 !   16.9   0.0   9.6e-07    0.0058      82     177 ..     134     231 ..     120     231 .. 0.83
   3 ?    3.3   0.0     0.015        89      12      28 ..     270     286 ..     263     312 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.058
      TAXi_N   1 YlvsisiGtppqplklvvDtGsdltWvqCkp 31 
                 Yl  i++G     l++++Dt  + +Wv+ k 
  EEA18459.1  83 YLSPIKVGRD--MLLVTFDTSTSDLWVKTKF 111
                 7778888887..8999***********9843 PP

  == domain 2  score: 16.9 bits;  conditional E-value: 9.6e-07
      TAXi_N  82 eisygadgssssGvlatdtltlsstdgksvkvpnlvfGCgk..snlgglaagadGilGLGrgklSlvsqlaskg........slgnkFsyCLsssssss 170
                 +++y+ d+s   G++ +d++++    g+ +++++ v +  +  + ++ +++ +dG+lGL++++l  v+ +++++          + +F+ CL   + + 
  EEA18459.1 134 QVRYP-DTSILGGDVYKDVVRV----GQVASFEQAVETLLYlhTPSSVFREVVDGVLGLAFSSLNTVQPIKQRTfydnvkpmLSNPVFAACL---KHNT 224
                 78998.999*************....56677777777766663445566667*******************9998998888778889*****...8888 PP

      TAXi_N 171 sgvlffG 177
                 +g+  fG
  EEA18459.1 225 PGFFDFG 231
                 8887777 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.015
      TAXi_N  12 qplklvvDtGsdltWvq 28 
                  p+ +vvDtGs+l+ ++
  EEA18459.1 270 NPFHAVVDTGSSLLLLR 286
                 5799********99775 PP

>> Dus  Dihydrouridine synthase (Dus)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   3.9e-05      0.24     197     223 ..     248     274 ..     243     302 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 3.9e-05
                 HHHHHHHHH--SEEEESCHHCCSTTHH CS
         Dus 197 daqaileetGadgvmigrgalgnPwlf 223
                 d ++  +++++dg migr+a  nP++ 
  EEA18459.1 248 DSSQGYWNITCDGFMIGRAASFNPFHA 274
                 667778999***************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (392 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       350  (0.0195214); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.37s 00:00:01.02 Elapsed: 00:00:00.57
# Mc/sec: 2064.92
//
Query:       EEA18460.1  [L=176]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-13   51.6   0.0    1.8e-13   51.0   0.0    1.3  1  HsbA      Hydrophobic surface binding protein A


Domain annotation for each model (and alignments):
>> HsbA  Hydrophobic surface binding protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.0   0.0     1e-17   1.8e-13      10     118 ..      42     145 ..      32     147 .. 0.89

  Alignments for each domain:
  == domain 1  score: 51.0 bits;  conditional E-value: 1e-17
                 HHHHHHHHHHHHHHH--S.H...HHHHHHHHHHHHHHHHHHHHHHHTS----HHHHHHHHHHHHHCHHHHHHHHHHHHHTHHHHHHHT-HHHHHHHHHH CS
        HsbA  10 tistavtaldtavnafnG.g.asalpilsasnalvsaikkattdaqasapltdeealalaqavqtLepdvkaaldaliaKkpafdkagltslvlssLqd 106
                 +       +  av++fn    + +  i+++++ +++ai+ ++      +pl + +a  l+ +   L++++k al ++i K++ +d++gl+++v ++L++
  EEA18460.1  42 D-------IRLAVDKFNKdIfLAIPDIHDDFDIIIAAIQRGMGRLGPEPPLIPFQARILIIPSLPLKTQIKEALRNVIRKRAIMDTSGLKPQVAQDLRR 133
                 4.......444666666653456999************************************************************************* PP

                 HHHHHHHHHHHH CS
        HsbA 107 lkaasdaLsdal 118
                 lkaa+++Ls  +
  EEA18460.1 134 LKAAAQQLSSLV 145
                 ********9866 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (176 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       409  (0.0228122); expected 358.6 (0.02)
Passed bias filter:                      349  (0.0194657); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.45
# Mc/sec: 1186.46
//
Query:       EEA18461.1  [L=1500]
Description: DNA helicase recq, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.9e-12   46.6  12.4    4.2e-12   46.5   9.6    2.6  2  OrsD          Orsellinic acid/F9775 biosynthesis cluster prot
    8.2e-12   45.5   0.0      1e-10   41.9   0.0    2.7  3  Helicase_C    Helicase conserved C-terminal domain
    4.6e-11   42.8   0.0    1.7e-10   41.0   0.0    2.0  1  DEAD          DEAD/DEAH box helicase
    0.00085   19.4   0.0      0.002   18.2   0.0    1.6  1  ResIII        Type III restriction enzyme, res subunit
     0.0091   16.7   0.1      0.032   14.9   0.1    2.0  1  RecQ_Zn_bind  RecQ zinc-binding
  ------ inclusion threshold ------
      0.035   13.7   3.0       0.19   11.3   3.0    2.3  1  zf-C2H2_12    Zinc-finger C2H2-type
       0.13   11.5   0.0       0.22   10.7   0.0    1.3  1  Peptidase_S8  Subtilase family


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.5   9.6   1.6e-15   4.2e-12       1     114 []       8     118 ..       8     118 .. 0.86
   2 ?   -2.0   0.0       1.8   4.6e+03      35      63 ..     504     531 ..     495     545 .. 0.71

  Alignments for each domain:
  == domain 1  score: 46.5 bits;  conditional E-value: 1.6e-15
        OrsD   1 dlfeyneeyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgL..pvyeGyrCrakakCky 97 
                 ++f+y++++r++iC  C++ v  s+l +HLr+  +  +    ++ ++ +  ++  +q+ e  r++ ++ +p+++ +pipgL  p    y+C   ++C++
  EEA18461.1   8 QIFQYDPHHRIVICCLCQHVVFDSQLPSHLRNTRHIRE----RHSQHIILFQQYHQQFPERIRHHRELVIPHKPIAPIPGLipPRDPTYQC-SYPGCHW 101
                 57*****************************5544443....34556665557788999999******************96555699***.78***** PP

        OrsD  98 ltrslktlrkHlqkkhg 114
                 +  +++++++H +++hg
  EEA18461.1 102 IGETIRRIHDHCRQEHG 118
                 **************995 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.8
        OrsD  35 rqlkrektqelletvehemslrqldelar 63 
                  q++r ++ +l+etv h    r +d+l++
  EEA18461.1 504 YQHHRFTMDQLRETV-HGIINRAWDHLTQ 531
                 456666788999999.8888899996644 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0       5.4   1.4e+04      16      54 ..     942     980 ..     939     986 .. 0.70
   2 ?   -0.6   0.0      0.65   1.7e+03      57      89 ..    1068    1101 ..    1037    1108 .. 0.83
   3 !   41.9   0.0   3.9e-14     1e-10      15     110 ..    1113    1212 ..    1100    1213 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 5.4
                 TSEEEEEESSHH.HHHHHHHHHHHTTSTEEEESTTSTHHH CS
  Helicase_C  16 ggkilifvntid.rlekvklllekkgikvavlhgelpqne 54 
                  g+++++v+t++ r ++ +    + gi++++ ++  p + 
  EEA18461.1 942 AGTSIVVVPTVSlRQDMQREC-AQAGISCVPWNSHRPPET 980
                 678899999999766543333.466899999998887765 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.65
                  HHHHHHH.TTSSSEEEESGGGTSSSTSTTESEEE CS
  Helicase_C   57 eileqfn.kgesdvLiatdvaerGidipkvnlVi 89  
                   ++++f+  ++++v ia +v ++++d+++ ++V 
  EEA18461.1 1068 TVVQRFRsPHTTRVNIAYRVESMSVDVDEDEVVA 1101
                  57899*944555599************9887776 PP

  == domain 3  score: 41.9 bits;  conditional E-value: 3.9e-14
                  TTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHH...TTS.....SS.EEEESGGGTSSSTSTTESEEEESSSSSSHHHHHH CS
  Helicase_C   15 eggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfn...kge.....sd.vLiatdvaerGidipkvnlVinfdlprnvtsyiq 102 
                  +gg+i+++   + ++   + l     + ++++hg++    +e++l++f    +g+     s   ++at+++++Gi+i  v++Vi++++p  +++y q
  EEA18461.1 1113 RGGQIIVYRSETGDV---DAL--ATRLGCLAYHGKMAVAMKEHALQAFTphpEGTtdpirSGmTIVATNALGMGINIRTVRCVIHVEVPSMLREYSQ 1204
                  677888888888888...455..4568999******************96654556666533479******************************** PP

                  HHTTSSST CS
  Helicase_C  103 riGRtgRa 110 
                   +GR+gR 
  EEA18461.1 1205 ESGRAGRD 1212
                  *******6 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.0   0.0   6.5e-14   1.7e-10       3     173 ..     904    1054 ..     902    1058 .. 0.77

  Alignments for each domain:
  == domain 1  score: 41.0 bits;  conditional E-value: 6.5e-14
                  HHHHHHHHHHTTC.EEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTC CS
                  xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD    3 iQaeaiplilggg.dvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngv 98  
                  iQ++ai++++g    vl+ + TG GK+++f++p+    +    +++   ++v+Pt +L +++ +++ + +      ++ + +  +         +++
  EEA18461.1  904 IQKAAIDAVMGSApWVLGVMGTGGGKSMIFMVPAA---W----ERAGTSIVVVPTVSLRQDMQRECAQAGIS----CVPWNSHRPP--------ETA 981 
                  9*********66559********************...4....456689*******************9994....2222222222........456 PP

                  SEEEEEHHHHHHHH.....HCTSSHCTTEEEEEEETHHHHHHT..TTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHH CS
                  xxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   99 divvgtpgrlddll.....stgklnlsqvrflVlDEadrlldq..gfsdfinrilnqlpqitcdgklqrqvivlSATlpkdv 173 
                  +iv+ tp+   +       s +  + +++  +V+DE++++ld+  +f++++  ++  +   t   +    v++l+ATlp  v
  EEA18461.1  982 RIVLVTPESATSKGfrsyiS-RLQERNRLDRIVIDECHTILDSreEFRPKMAGLHVLM---TIGSP----VVLLTATLP-AV 1054
                  78999998888844354432.2223788899***********9888888888877777...44445....********9.44 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0   7.8e-07     0.002      29     147 ..     921    1023 ..     900    1053 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 7.8e-07
                  EEESTTSTHHHHH.HHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--.......-SEEEEEHHHHHHTH...... CS
      ResIII   29 ikmaTGtGKTlva.aklierllkkgkeekflflvprkslleqtleefkkflseaykeigkkvsgdkkkakekdstnkkilvttiqsldadseeeeee 124 
                   +m TG GK+++  + ++++ +        +++vp+ sl + +++e ++   +++      +++ +  +      +++i+++t +s++++   +++ 
  EEA18461.1  921 GVMGTGGGKSMIFmVPAAWERAG-----TSIVVVPTVSLRQDMQRECAQAGISCV-----PWNSHRPPE------TARIVLVTPESATSKG-FRSYI 1000
                  5899******9985677777776.....689********************9875.....677777777......9999999999999988.56999 PP

                  ..HHHTTT-SEEEEETGGGTTS. CS
      ResIII  125 seellrdrfdviiiDEaHrlgak 147 
                  s  ++r+r d i+iDE+H + ++
  EEA18461.1 1001 SRLQERNRLDRIVIDECHTILDS 1023
                  9999**************98875 PP

>> RecQ_Zn_bind  RecQ zinc-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.1   1.3e-05     0.032      26      65 ..    1240    1282 ..    1213    1283 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.3e-05
  RecQ_Zn_bind   26 ekleamlaycentteCrrkllleyFgeeaaeeeC..gn..CDnC 65  
                    e+ +am +y + t+ Crr +l  y +  +  + C  g+  CD C
    EEA18461.1 1240 ERKQAMREYFHGTR-CRRAVLDAYLDSYERPDGCtdGEapCDQC 1282
                    56799*****6666.**********98777778*662266**99 PP

>> zf-C2H2_12  Zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   3.0   7.4e-05      0.19      14      59 ..      10      58 ..       6      64 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 7.4e-05
  zf-C2H2_12 14 mdydpqrrglvCmvCgeslaslkl.stik..rHIrqvHPeslslseeek 59
                  ydp++r ++C  C+++    +l s+++  rHIr++H + + l ++ +
  EEA18461.1 10 FQYDPHHRIVICCLCQHVVFDSQLpSHLRntRHIRERHSQHIILFQQYH 58
                68***************999999844554338******99877766655 PP

>> Peptidase_S8  Subtilase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   8.7e-05      0.22      47      88 ..     795     838 ..     712     847 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 8.7e-05
                   -SS-TT-SC-SSS......HHHHHHHHHH-B..SSSSSB-SSTT CS
                   xxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8  47 ettstnwarddngnsie..HGthvAGiaaanapeegekngvapg 88 
                   ++    w++dd + +i+  HG+hvAG++ a   ee      a +
    EEA18461.1 795 DEDGCWWTADDAVIDIQagHGSHVAGMIYARGVEEAPGTMAAMK 838
                   3444457778887777799**********995555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1500 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       660  (0.0368119); expected 358.6 (0.02)
Passed bias filter:                      457  (0.0254894); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.91u 0.28s 00:00:01.19 Elapsed: 00:00:00.49
# Mc/sec: 9211.85
//
Query:       EEA18462.1  [L=489]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.3e-207  689.8   2.0   1.6e-207  689.5   2.0    1.1  1  LA-virus_coat  L-A virus, major coat protein
     0.0055   17.1   0.2      0.011   16.1   0.2    1.5  1  Herpes_HEPA    Herpesvirus DNA helicase/primase complex assoc


Domain annotation for each model (and alignments):
>> LA-virus_coat  L-A virus, major coat protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  689.5   2.0  1.8e-211  1.6e-207      64     439 .]       1     374 [.       1     374 [. 0.99

  Alignments for each domain:
  == domain 1  score: 689.5 bits;  conditional E-value: 1.8e-211
                    EE------TTSBCCCB-SSSSB-HHHHHCCHHHTSS--CCHHHHHHHHCTTT----B-CCHHHHHHHHHHHHHHHHTT---------EE-SSEEE- CS
  LA-virus_coat  64 lsevessleglakkyltldgalaidnvlqelkssagiqsnivashaynvaswrwydnhvallvnllrayilsvldersklsagdipvyddghvkid 159
                    +se+essl+gl+kkyltldga+++dnv+ elk+ ag+q+ ++++haynva+w+wydnhv+llvnllr+yils+l+er+ l++g++p+yddg v+id
     EEA18462.1   1 MSEAESSLDGLNKKYLTLDGAISTDNVFAELKNLAGFQTSVISGHAYNVAGWKWYDNHVSLLVNLLRFYILSDLHERTSLTTGKYPIYDDGNVIID 96 
                    89********************************************************************************************** PP

                    ---S..S-TTTS-SS---SS-TTTS---EEEEE--SS-SSSS-EEE-TTS-HHHHHHHHHHCS-B---SSBGGG--B--S-SEEEEE-SS---CCH CS
  LA-virus_coat 160 lnvtllledkagpvdfawpsdradesypdwaqlseslpvidvpyldlrpltveevkvvlmmtskwkrrtnlkldyeaprlaekiayryaltvsdld 255
                    ln tl +++k   vd++wp++r desyp w++++e+lpv+d+p++dlrplt+ee+k+vlmmt++wk++tn+kld+++prla+ki+yr++ ++s+l+
     EEA18462.1  97 LNPTLEFDNKE--VDWTWPGRRMDESYPFWSPIAEFLPVTDDPHIDLRPLTEEEAKIVLMMTGEWKPQTNYKLDFYTPRLADKIMYRFRSPISSLN 190
                    ****9999998..*********************************************************************************** PP

                    HHCCSSS-TCCC----HHHHHHHHHHHHHHCT-HHHHHHHHHHHHHCS-EE--SSCGGGCTTTS--EEEEE--B-BTTSSCCCT-SSEEEEEHHHH CS
  LA-virus_coat 256 ewleaertddtyrlpkskvilsalrkyvthnrlynqfytaaqllaqvmlkvvpdtaegyawlthvaevnlpkfgsvrgrypfllsgeaaliqakal 351
                    +wl+ e   + y+lpk kvi+ alrkyvt+n+lynqfyta++++aqvml+v+pdtaeg++wlthv+ev+lpkfgsvrg ypfl+sgeaa+iqakal
     EEA18462.1 191 DWLDPEDVGPVYFLPKPKVIWNALRKYVTYNNLYNQFYTATNIIAQVMLTVFPDTAEGMTWLTHVPEVHLPKFGSVRGWYPFLNSGEAAFIQAKAL 286
                    ************************************************************************************************ PP

                    HHHHHHHH-THHHHHHHHHHHHHHHHHHHHHHHHCCTTTTSSS-TTTTCGGGSHHHHHHHHHHHHCSSEEE--SSSS-EEE-GGGSST CS
  LA-virus_coat 352 edwaaliakpellftyamqlavalniglalrdvkkslliteiddsyedtlfltpetfvaaalalatgldaplngmsdvyvtypellei 439
                    edwaalia pellftyam+la++lnigla+rd+k+s li+e++++++dtlfltpetf+a+a++latgldaplngm+dvyv+ypel+++
     EEA18462.1 287 EDWAALIAEPELLFTYAMMLASTLNIGLAVRDAKASRLIGEVKSTFDDTLFLTPETFFASAVSLATGLDAPLNGMADVYVFYPELVNV 374
                    **************************************************************************************96 PP

>> Herpes_HEPA  Herpesvirus DNA helicase/primase complex associated protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.2   1.3e-06     0.011      37      92 ..     207     263 ..     201     266 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 1.3e-06
  Herpes_HEPA  37 desksnlal.laffralhekvfgekevlapiflyigPelnpegedvdyfasvgfpgf 92 
                  +++ +n +   +++  l+++ + +++++a+++l ++P++ +  + +++  +v++p f
   EEA18462.1 207 PKVIWNALRkYVTYNNLYNQFYTATNIIAQVMLTVFPDTAEGMTWLTHVPEVHLPKF 263
                  5666765441579**************************999888888888888877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (489 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       379  (0.0211389); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 3110.16
//
Query:       EEA18463.1  [L=143]
Description: hypothetical protein PMAA_050140 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (143 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       300  (0.0167327); expected 358.6 (0.02)
Passed bias filter:                      276  (0.0153941); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 1003.71
//
Query:       EEA18464.1  [L=489]
Description: hypothetical protein PMAA_102410 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.9e-10   39.9   1.3    9.8e-10   38.9   0.2    2.0  2  OrsD        Orsellinic acid/F9775 biosynthesis cluster protei
     0.0023   17.4   0.1       0.06   12.9   0.0    2.7  3  zf-C2H2_12  Zinc-finger C2H2-type
  ------ inclusion threshold ------
      0.032   14.3   0.9      0.032   14.3   0.9    2.7  3  zf-BED      BED zinc finger
        1.2    9.8   3.9         20    5.9   0.2    3.7  4  ITAM        Immunoreceptor tyrosine-based activation motif


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.9   0.2   2.2e-13   9.8e-10       8     114 .]      21     116 ..      17     116 .. 0.89
   2 ?   -2.3   0.1       1.3   5.8e+03      25      58 ..     167     200 ..     157     206 .. 0.55

  Alignments for each domain:
  == domain 1  score: 38.9 bits;  conditional E-value: 2.2e-13
        OrsD   8 eyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgLpvyeGyrCrakakC.kyltrslktl 105
                 ++r+liC++C +a+ p+++++H  ++h+    e+++ l e++      rq d   +e++ v +++      p L +y+G+ C     C +y t +l++l
  EEA18464.1  21 NFRLLICESCGFALGPNQASSHFWEKHQVS-VEQRHGLTEYL------RQHD--FQEPASVAPRPRGASEHPALRTYNGLAC---RLCeTYYTINLDNL 107
                 5799********************998887.666899**999......8888..789999999999999999**********...56736********* PP

        OrsD 106 rkHlqkkhg 114
                  kHl+++h+
  EEA18464.1 108 LKHLRHQHP 116
                 ******995 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1.3
        OrsD  25 elerHLrkrhrqlkrektqelletvehemslrql 58 
                 +l++  r+rh  ++ +++q    ++  ++slr++
  EEA18464.1 167 ALQERERTRHAAIQAATVQDSGIATRSFESLRPW 200
                 3344445555555555555544444444555555 PP

>> zf-C2H2_12  Zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.0     0.065   2.9e+02      19      38 ..      21      40 ..      13      65 .. 0.67
   2 !   12.9   0.0   1.3e-05      0.06      21      55 ..      89     122 ..      86     134 .. 0.85
   3 ?   -3.0   0.0       1.2   5.5e+03      10      20 ..     346     356 ..     342     368 .. 0.76

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.065
  zf-C2H2_12 19 qrrglvCmvCgeslaslkls 38
                + r l+C  Cg +l   + s
  EEA18464.1 21 NFRLLICESCGFALGPNQAS 40
                56789*****9998766554 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 1.3e-05
  zf-C2H2_12  21 rglvCmvCgeslaslklstikrHIrqvHPeslsls 55 
                 +gl C  C+ + ++++l+++ +H r++HP+  + s
  EEA18464.1  89 NGLACRLCE-TYYTINLDNLLKHLRHQHPDRPRSS 122
                 79******7.579****************976655 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 1.2
  zf-C2H2_12  10 leyLmdydpqr 20 
                 ++ L+dy+p+ 
  EEA18464.1 346 QDLLLDYHPSI 356
                 57799999975 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0      0.38   1.7e+03      19      43 ..      27      47 ..      25      48 .. 0.60
   2 ?   -3.0   0.1       1.7   7.7e+03      28      38 ..      54      64 ..      53      64 .. 0.84
   3 ?   14.3   0.9     7e-06     0.032      17      44 .]      91     116 ..      80     116 .. 0.90

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.38
                ETTTTEE----SSTHHHHHHHHHS- CS
      zf-BED 19 CryCgkilsrgggttnLkrHLrrkH 43
                C  Cg+ l    g +  ++H + kH
  EEA18464.1 27 CESCGFAL----GPNQASSHFWEKH 47
                66677665....4556666666666 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.7
                --SSTHHHHHH CS
      zf-BED 28 rgggttnLkrH 38
                r+g t +L++H
  EEA18464.1 54 RHGLTEYLRQH 64
                667899****9 PP

  == domain 3  score: 14.3 bits;  conditional E-value: 7e-06
                 -EETTTTEE----SSTHHHHHHHHHS-H CS
      zf-BED  17 avCryCgkilsrgggttnLkrHLrrkHp 44 
                   Cr C+  ++   +  nL +HLr++Hp
  EEA18464.1  91 LACRLCETYYTI--NLDNLLKHLRHQHP 116
                 57**********..8************8 PP

>> ITAM  Immunoreceptor tyrosine-based activation motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.1     0.072   3.2e+02       3      15 ..      87      99 ..      87     103 .. 0.86
   2 ?    5.9   0.2    0.0044        20       7      19 ..     153     166 ..     152     167 .. 0.90
   3 ?   -1.3   0.0      0.89     4e+03       5      12 ..     166     173 ..     166     174 .. 0.89
   4 ?   -0.5   0.0      0.47   2.1e+03      13      19 ..     208     214 ..     203     215 .. 0.68

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.072
        ITAM  3 lYqpLnkrdrdtY 15
                +Y++L  r ++tY
  EEA18464.1 87 TYNGLACRLCETY 99
                5***********9 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0044
        ITAM   7 Lnkrd.rdtYShLg 19 
                 L++++ r+tY+hL+
  EEA18464.1 153 LRLAQeRSTYDHLQ 166
                 899999*******7 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.89
        ITAM   5 qpLnkrdr 12 
                 q+L++r+r
  EEA18464.1 166 QALQERER 173
                 99****97 PP

  == domain 4  score: -0.5 bits;  conditional E-value: 0.47
        ITAM  13 dtYShLg 19 
                  tY++L+
  EEA18464.1 208 QTYDGLH 214
                 4777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (489 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       488  (0.0272185); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.57u 0.23s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3406.88
//
Query:       EEA18465.1  [L=126]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      4e-05   24.1   1.2      0.049   14.2   0.3    2.2  2  HTH_32        Homeodomain-like domain
    0.00069   19.3   0.2     0.0011   18.7   0.2    1.3  1  HTH_23        Homeodomain-like domain
     0.0022   17.7   0.1     0.0045   16.7   0.1    1.5  1  HTH_38        Helix-turn-helix domain
     0.0059   16.7   0.0        1.6    8.9   0.0    2.2  2  HTH_7         Helix-turn-helix domain of resolvase
  ------ inclusion threshold ------
      0.041   14.1   0.0      0.062   13.5   0.0    1.3  1  DUF2774       Protein of unknown function (DUF2774)
      0.056   14.6   0.0       0.11   13.7   0.0    1.6  1  Cytochrom_C   Cytochrome c
       0.07   12.8   0.0       0.11   12.2   0.0    1.3  1  Sigma70_r4_2  Sigma-70, region 4


Domain annotation for each model (and alignments):
>> HTH_32  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   0.0   0.00076       1.9      15      68 ..      16      65 ..      11      70 .. 0.74
   2 !   14.2   0.3   1.9e-05     0.049      18      44 ..      76     101 ..      67     118 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00076
      HTH_32 15 egLkdrprrg..rpr..klsdevrariiallreeprWsprqlaarlaeregvkvShst 68
                eg ++++++g  +p   +l+ + r ri+ l+ e+  +++ q+a +l       + h +
  EEA18465.1 16 EGAREAASGGesKPYstRLNRDDRIRILTLR-EA-GFTYLQIASQL------HITHDQ 65
                566666666664554778*************.77.8********99......344443 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 1.9e-05
      HTH_32  18 kdrprrgrprklsdevrariiallree 44 
                  +++ rgr++kls+e ++r+i+++ + 
  EEA18465.1  76 TPKKARGRTPKLSEEDVDRVIDWI-SS 101
                 689999*****************9.43 PP

>> HTH_23  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.2   4.3e-07    0.0011       5      35 ..      37      67 ..      33      75 .. 0.91

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 4.3e-07
      HTH_23  5 reRlrillllaeGlsvreIAreLgvsrrTvy 35
                ++R+ril l   G ++ +IA +L++++ +v+
  EEA18465.1 37 DDRIRILTLREAGFTYLQIASQLHITHDQVQ 67
                78*************************9998 PP

>> HTH_38  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.1   1.8e-06    0.0045       4      31 ..      33      60 ..      31      64 .. 0.91

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 1.8e-06
      HTH_38  4 hLsleeReeIerllaeGlslreIArrLg 31
                +L+ ++R +I +l+++G ++ +IA +L+
  EEA18465.1 33 RLNRDDRIRILTLREAGFTYLQIASQLH 60
                8999*********************997 PP

>> HTH_7  Helix-turn-helix domain of resolvase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.9   0.0   0.00062       1.6       7      37 ..      35      65 ..      32      67 .. 0.85
   2 !    5.8   0.0    0.0057        15       1      15 [.      82      96 ..      82     100 .. 0.94

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00062
                -HHHHGGGGSSTTTT--STTTSSSS---SSS CS
       HTH_7  7 skndinrvvkLleeGisiskIAkevnisRsT 37
                +++d  r+++L+e+G +  +IA ++ i+  +
  EEA18465.1 35 NRDDRIRILTLREAGFTYLQIASQLHITHDQ 65
                66667799*****************999765 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0057
                S---SS-HHHHGGGG CS
       HTH_7  1 GRpsklskndinrvv 15
                GR +kls++d +rv+
  EEA18465.1 82 GRTPKLSEEDVDRVI 96
                9************97 PP

>> DUF2774  Protein of unknown function (DUF2774)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   2.4e-05     0.062       3      31 ..      39      67 ..      37      84 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.4e-05
     DUF2774  3 kvqvhflhesgknFveIAkkldirakdva 31
                ++++ +l+e+g+ + +IA +l i+  +v 
  EEA18465.1 39 RIRILTLREAGFTYLQIASQLHITHDQVQ 67
                578999*****************988775 PP

>> Cytochrom_C  Cytochrome c
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   4.3e-05      0.11      37      92 .]      49     103 ..       6     103 .. 0.74

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 4.3e-05
                  HTTT-HHHHHHHHTTSS--SSSHHHHHHHGGGGGGG.TT--HHHHHHHHHHHHTT- CS
  Cytochrom_C  37 rasaasigasvanpaavsaprddfekkkltaemparkerlteqeiadlaaYLkslk 92 
                    ++ +i ++ +  + + + ++  +++++ ++++ r ++l+e++++ ++ +++s k
   EEA18465.1  49 GFTYLQIASQLHITHDQVQYTCQSQQATP-KKARGRTPKLSEEDVDRVIDWISSSK 103
                  45666677777777666666665555554.34445559**************9975 PP

>> Sigma70_r4_2  Sigma-70, region 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   4.2e-05      0.11      17      40 ..      41      63 ..      32      69 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 4.2e-05
                  HHHHHHHTS---HHHHHHHHT--H CS
  Sigma70_r4_2 17 eifllryleglsykEIAellgise 40
                  +i++l ++ g++y +IA++l+i+ 
    EEA18465.1 41 RILTL-REAGFTYLQIASQLHITH 63
                  46666.89*************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (126 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       656  (0.0365888); expected 358.6 (0.02)
Passed bias filter:                      518  (0.0288917); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.46
# Mc/sec: 829.99
//
Query:       EEA18466.1  [L=332]
Description: hypothetical protein PMAA_102430 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        1.5    8.9   3.4       0.79    9.7   0.6    2.0  3  DUF4192   Domain of unknown function (DUF4192)


Domain annotation for each model (and alignments):
>> DUF4192  Domain of unknown function (DUF4192)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0     0.094   1.7e+03     144     191 ..      32      74 ..      28     102 .. 0.65
   2 ?    9.7   0.6   4.4e-05      0.79     173     252 ..     136     215 ..      89     226 .. 0.75
   3 ?   -3.7   0.0      0.52   9.3e+03     144     179 ..     276     310 ..     270     315 .. 0.62

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.094
     DUF4192 144 vegsReelearlapvega.aaraaqrraaeraaaaleralarprdaerr 191
                 ++ s +++ea+++pv+++ +        +  +a+ +er ++r++ + r+
  EEA18466.1  32 PRQSSTPIEALFTPVTPNcE------TSQTPIAPSIERSQLREASQLRN 74 
                 67788889999999977633......23345556666666655555554 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 4.4e-05
     DUF4192 173 raaaaleralarprdaerrsdpaevrraaleavraalarvaagaglsdaeeaarlavaLtdvrvRDaalalalgeeaaaa 252
                 +a+ ++++a +++ +  r+ +++   + a++++ + l+++ + ++ ++a++++++    ++v  RD +l+ ++++ ++ a
  EEA18466.1 136 EARVRAREAYTQKYETGRETEASTPLDVAIDEWIEFLQEYSEEEKEESAQKTQDILFQQQQVLYRDGLLETMEKAAKRRA 215
                 22222222222222333337789999*******************99999**********************96555544 PP

  == domain 3  score: -3.7 bits;  conditional E-value: 0.52
     DUF4192 144 vegsReelearlapvegaaaraaqrraaeraaaale 179
                 +  +R+ + ++++p    ++++a +++++ ++++++
  EEA18466.1 276 LKQDRRLIKSLITPSSN-KDHDALAQQVKNISKRVD 310
                 55677777777777544.445555665666666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (332 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1907  (0.106364); expected 358.6 (0.02)
Passed bias filter:                      597  (0.033298); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.46
# Mc/sec: 2175.51
//
Query:       EEA18467.1  [L=614]
Description: reverse transcriptase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-07   31.7   0.1    2.4e-07   30.6   0.1    1.5  1  Exo_endo_phos_2  Endonuclease-reverse transcriptase
    1.8e-06   27.6   0.0    3.4e-06   26.8   0.0    1.4  1  RVT_1            Reverse transcriptase (RNA-dependent DNA pol
    5.1e-06   26.7   0.0    9.7e-06   25.8   0.0    1.4  1  RNase_H          RNase H
  ------ inclusion threshold ------
       0.12   11.4   0.0       0.19   10.8   0.0    1.2  1  Toxin_trans      Clostridium neurotoxin, Translocation domain


Domain annotation for each model (and alignments):
>> Exo_endo_phos_2  Endonuclease-reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.6   0.1   5.2e-11   2.4e-07      54     118 ..      37     103 ..      25     104 .. 0.86

  Alignments for each domain:
  == domain 1  score: 30.6 bits;  conditional E-value: 5.2e-11
  Exo_endo_phos_2  54 sargeeLiefleehslsllnllksg.ptfkssngsstiDltltsdnlals...kleleeedlgSDHrpi 118
                      + +g+eL+e+ + h++ l+   ++g  t+++s+++stiDlt+ s +l ++    ++    ++ SDH pi
       EEA18467.1  37 DTEGTELLEIADRHEIDLAT--EQGmVTWERSQSKSTIDLTFLSGSLFNRlilIERADSVQHDSDHWPI 103
                      589**************444..4555************************99977777789******98 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.0   7.5e-10   3.4e-06     111     169 ..     391     449 ..     374     455 .. 0.90

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 7.5e-10
                 ..............TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T......TEEECTTE CS
       RVT_1 111 trsfsvrv.ngeeskgryekkglpqGsvlSPllfnlfmnellrelrkrakgvtllrYaDD 169
                  rs+++++ +g  s+++ +++g+pqGs++SP+l+ ++ ++l+++++ +a+ v ++  +DD
  EEA18467.1 391 RRSTRIKIpEGI-SERISTSTGIPQGSPISPILYLIYNSDLIEDCADEANHVSTSGWVDD 449
                 578899995565.59********************************************9 PP

>> RNase_H  RNase H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   0.0   2.2e-09   9.7e-06     111     142 ..     568     599 ..     550     600 .. 0.83

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 2.2e-09
                 HC.SSEEEEEE-SCCSSSTHHHHHHHHHHHHHH CS
     RNase_H 111 ak.kkkvqlkwvkgHaGvpkgNemaDrlAkeaa 142
                 ++   +v l+w++gH+G+p gNe+aDr+Ak+aa
  EEA18467.1 568 VDeGIDVVLHWIPGHEGIP-GNEAADRAAKRAA 599
                 44367899**********9.**********986 PP

>> Toxin_trans  Clostridium neurotoxin, Translocation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   4.2e-05      0.19      52      94 ..     420     462 ..     414     482 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 4.2e-05
                  TTTCCHCCHHCHHHHHHHHT--EE-TTSTT-SEE-TTHHHHHT CS
  Toxin_trans  52 aalflgwvkqivddftdeaskkstidkiadislivpyiGpaln 94 
                   +l+l +  ++++d +dea+++st   + d s  v y+G  l+
   EEA18467.1 420 PILYLIYNSDLIEDCADEANHVSTSGWVDDASKAVKYLGIWLD 462
                  5899999********************************9886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (614 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       337  (0.0187964); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 3992.99
//
Query:       EEA18468.1  [L=236]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (236 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       500  (0.0278878); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 1658.15
//
Query:       EEA18469.1  [L=180]
Description: hypothetical protein PMAA_102460 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.3e-05   22.8   0.0      9e-05   22.4   0.0    1.1  1  Bys1      Blastomyces yeast-phase-specific protein


Domain annotation for each model (and alignments):
>> Bys1  Blastomyces yeast-phase-specific protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.4   0.0     5e-09     9e-05      15     144 ..      25     156 ..      13     165 .. 0.71

  Alignments for each domain:
  == domain 1  score: 22.4 bits;  conditional E-value: 5e-09
        Bys1  15 vlvycnfsvaldveagevstrkildgrsydyynekyrggsgdgvsltls.htegrdssnsettfrykladdnstveyslgnsggnpfeghkltlks... 109
                 v+  c f v++       s   +ld   y  y+e+ r  s  gv + ++   eg  +s  +  f y      + ++y+l n  g+pf  h lt+++   
  EEA18469.1  25 VYNQCLFRVFVWTLGSSGSQNVLLD--PYTQYREDLRRSSNGGVDIKFTlDPEGVLTSSPQLRFTY--NKLGADIQYTLNNLYGEPFYNHPLTVNPlag 119
                 4445888888776555555555555..588899999999999999876524577776666666666..4556779******************887322 PP

        Bys1 110 sddrcpriewpegi.ptgvs.sgscgssenliltlcp 144
                  +  c  i w  g  p g +    c     + l lc 
  EEA18469.1 120 YGHFCRDIHWRRGTrPDGYTrKRNCRLLTAFHLHLCS 156
                 5788******998646675513456666666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (180 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       405  (0.0225891); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.23s 00:00:00.64 Elapsed: 00:00:00.39
# Mc/sec: 1401.23
//
Query:       EEA18470.1  [L=476]
Description: hypothetical protein PMAA_102470 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (476 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       365  (0.0203581); expected 358.6 (0.02)
Passed bias filter:                      309  (0.0172346); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.52u 0.24s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 3296.05
//
Query:       EEA18471.1  [L=357]
Description: hypothetical protein PMAA_102480 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (357 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       620  (0.0345808); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2314.40
//
Query:       EEA18472.1  [L=96]
Description: hypothetical protein PMAA_102490 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (96 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       469  (0.0261587); expected 358.6 (0.02)
Passed bias filter:                      405  (0.0225891); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.35u 0.25s 00:00:00.60 Elapsed: 00:00:00.38
# Mc/sec: 755.51
//
Query:       EEA18473.1  [L=96]
Description: hypothetical protein PMAA_102500 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.041   13.8   0.1      0.066   13.1   0.1    1.3  1  SH3_17    Restriction endonuclease SH3 domain


Domain annotation for each model (and alignments):
>> SH3_17  Restriction endonuclease SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.1   3.7e-06     0.066       5      30 ..      31      56 ..      27      58 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 3.7e-06
      SH3_17  5 dFVIankqldnvvkNSVGvikAlNGk 30
                +F    k++ +vvk  +G++k + G+
  EEA18473.1 31 EFLTLVKDILDVVKDIIGIVKTIRGQ 56
                788899*****************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (96 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       459  (0.025601); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.30s 00:00:00.77 Elapsed: 00:00:00.49
# Mc/sec: 586.41
//
Query:       EEA18474.1  [L=499]
Description: hypothetical protein PMAA_102510 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.2e-07   31.8   0.2    2.7e-07   30.8   0.2    1.5  1  Myb_DNA-bind_6   Myb-like DNA-binding domain
    4.1e-05   23.7   0.2    7.4e-05   22.9   0.2    1.5  1  Myb_DNA-binding  Myb-like DNA-binding domain


Domain annotation for each model (and alignments):
>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.8   0.2     3e-11   2.7e-07       1      50 [.     394     443 ..     394     448 .. 0.94

  Alignments for each domain:
  == domain 1  score: 30.8 bits;  conditional E-value: 3e-11
  Myb_DNA-bind_6   1 WteeEdeiLlklvekygndWknIaealnrRtpkqcfdrwknkLrpkisrk 50 
                     Wt+eEd +L  l ek +  W++I ++++ R + ++++r+ n+Lr++ s++
      EEA18474.1 394 WTDEEDARLKLLKEKDNLSWSQILKHFPGRKQGTLQFRYYNVLRDSTSKS 443
                     ****************9**********55****************99987 PP

>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.2   8.3e-09   7.4e-05       1      46 []     391     436 ..     391     436 .. 0.89

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 8.3e-09
                      CSSSBHHHHHHHHHHHHHHTTC..HHHHHHHHTSS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgkWteeEdelLleavkkhGnr..WkkIaerlggRtekqcrsrwrnyl 46 
                      +++Wt eEd +L  + +k  ++  W+ I+++++gR     + r++n+l
       EEA18474.1 391 KKAWTDEEDARLKLLKEK--DNlsWSQILKHFPGRKQGTLQFRYYNVL 436
                      689*********888888..4455*********************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (499 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       598  (0.0333538); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.52
# Mc/sec: 2864.43
//
Query:       EEA18475.1  [L=458]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-11   43.9   0.0    4.9e-11   43.0   0.0    1.4  1  APH       Phosphotransferase enzyme family


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.0   0.0   2.7e-15   4.9e-11      17     209 ..      72     334 ..      58     370 .. 0.60

  Alignments for each domain:
  == domain 1  score: 43.0 bits;  conditional E-value: 2.7e-15
                 EETT--EEEEEE-TT.....S-HHHHHHHHHHHHHHH.HTT-B--B-CTTB..S-EEETTEEEEEEE----EE-SS..............HHHHHHHHH CS
         APH  17 ttpagryvlrrnppa.....raaeeirrevallrlLa.kagvpvPevlagd..tddeeigllfalieyvpgrsllr..............klsaaqlpe 93 
                 ++++ + + r++ p+     + +e++++ev+++ +L+ ++++p+P+v+ ++      +++ +f ++ yv+g  l++                + ++l++
  EEA18475.1  72 NDGGPDAIIRFPKPGhtataYRDEKVANEVQIMEYLRqNTNIPIPRVHSWGliAESPHQLGPFIIMDYVEGVLLSTilkqpdqedvilnpDVDNNILDK 170
                 444447888887777665667888999**********77777******6553345555555*************************6655555555566 PP

                 HHHHHHHHHC..................................CHHCH.............-STTTB-SHHCHTCCHHHHHHCHHHCCCGCCTCCHHH CS
         APH  94 llealgefla..................................alhqv...........d.paalpladflaqdlellrqlesatarllaselldlle 146
                 ++++++ ++                                   +   +           + +++++ +d+l++ ++++ + + +     +++l d+ e
  EEA18475.1 171 IYRQIAYYILqlsqltfprigaiskdrasdtwhvagrpltynmnE---LatvagypnsqfPiAPFDRASDYLRS-VANEHLTHLW----TQRNLADDPE 261
                 666666666644444444444444444444333333333333331...03333222222233334444444444.3333444444....3333333334 PP

                 HHHHH..HHHHHHHH--S.....SS-EEEE-SS-SGGGEEEC..TTEEEEE---TT-EEEECCHHH...HCCH CS
         APH 147 eleeq..vlaalaallpg.....elptvllHgDlhpgNllvdpddgrvtGviDfedaglgpplyDl...avll 209
                  + e+  ++ ++a+l +      ++p  l   D +p N+lvdp    +t+++D+e++ ++p+ +     ++ll
  EEA18475.1 262 IAKERfiARHRFAQLIQQhciedSGPYILFCDDMRPSNMLVDPKTLNITAILDLEFTNAMPAEFTYdppWWLL 334
                 444444344455555555888855555555555*********************9987777654333365555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (458 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       412  (0.0229795); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.50
# Mc/sec: 2732.03
//
Query:       EEA18476.1  [L=61]
Description: hypothetical protein PMAA_102530 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.67    9.6  16.8       0.78    9.4  16.8    1.0  1  Casc1_N   Cancer susceptibility candidate 1 N-terminus
       0.69    9.2   9.2       0.74    9.1   9.2    1.1  1  U79_P34   HSV U79 / HCMV P34
        2.2    8.3   9.8        2.5    8.1   9.8    1.1  1  DUF3043   Protein of unknown function (DUF3043)
        2.6    8.0   8.9        6.6    6.7   8.9    1.6  1  DUF4574   Ubiquinol-cytochrome-c reductase complex assembly f
        4.9    7.1  12.2        4.2    7.3   1.9    2.3  2  UvrB      Ultra-violet resistance protein B
        8.1    6.1   5.4        8.3    6.1   5.4    1.0  1  Connexin  Connexin


Domain annotation for each model (and alignments):
>> Casc1_N  Cancer susceptibility candidate 1 N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4  16.8   0.00026      0.78       5      37 ..      13      46 ..      10      56 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00026
     Casc1_N  5 eeEeeRlraeeeererleeerrekeereql.aae 37
                 eEeeR+r+ +ee +r++ee+r+k+e e++ ++ 
  EEA18476.1 13 DEEEERMRKAAEESQRKREEARKKREMEEAmKKA 46
                69*********************99998877332 PP

>> U79_P34  HSV U79 / HCMV P34
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   9.2   0.00025      0.74     145     186 ..      13      54 ..       2      58 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00025
     U79_P34 145 kegraldrkkaddeqrkrsgkqkekrkvedidkkk.edekrke 186
                 +e   + rk a++ qrkr    ++kr +e+  kk  ed +r++
  EEA18476.1  13 DEEEERMRKAAEESQRKR-EEARKKREMEEAMKKAgEDSQRRR 54 
                 556677899999999999.666777888777766525556553 PP

>> DUF3043  Protein of unknown function (DUF3043)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   9.8   0.00085       2.5      23      62 ..      19      58 ..       6      60 .. 0.72

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00085
     DUF3043 23 pktrkearkrareaarerrerareamraGderylpardrg 62
                 ++ +e+ +r+re+ar++re +++  +aG++++   rd g
  EEA18476.1 19 MRKAAEESQRKREEARKKREMEEAMKKAGEDSQRRRRDGG 58
                3344566666699999999998888889999999999976 PP

>> DUF4574  Ubiquinol-cytochrome-c reductase complex assembly factor 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   8.9    0.0022       6.6      29      71 ..      10      50 ..       7      59 .. 0.74

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0022
     DUF4574 29 tPgeerkqeilkempeqdpqrrdeaakkkaLvlatLqeAaatq 71
                 P++e  +++ k ++ +++++r+ea+kk++ + + +++A +++
  EEA18476.1 10 VPNDEEEERMRKAAE-ESQRKREEARKKRE-MEEAMKKAGEDS 50
                69*********9988.56677788555555.556777777665 PP

>> UvrB  Ultra-violet resistance protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   2.9    0.0058        17      10      22 ..      19      31 ..      13      35 .. 0.89
   2 ?    7.3   1.9    0.0014       4.2       6      22 ..      39      55 ..      37      56 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0058
                HHHHHHHHHHHHH CS
        UvrB 10 MkkAideTerRRe 22
                M+kA +e +r+Re
  EEA18476.1 19 MRKAAEESQRKRE 31
                ************8 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0014
                --HHHHHHHHHHHHHHH CS
        UvrB  6 iTdSMkkAideTerRRe 22
                + ++MkkA ++ +rRR+
  EEA18476.1 39 MEEAMKKAGEDSQRRRR 55
                6689************6 PP

>> Connexin  Connexin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   5.4    0.0028       8.3     107     148 ..      14      55 ..       6      61 .] 0.50

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0028
    Connexin 107 keeeekeeeekeeekkkkkekkkkkkkeeekekkkeegkrri 148
                 +eee++++  +e+++k+++ +kk++++e+ k++ +++++rr 
  EEA18476.1  14 EEEERMRKAAEESQRKREEARKKREMEEAMKKAGEDSQRRRR 55 
                 244445555555555554455555555555555444444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (61 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2865  (0.159797); expected 358.6 (0.02)
Passed bias filter:                     1186  (0.0661498); expected 358.6 (0.02)
Passed Vit filter:                       171  (0.00953762); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.47u 0.30s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 401.20
//
Query:       EEA18477.1  [L=263]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      3e-18   66.1   0.0      4e-18   65.7   0.0    1.1  1  Pkinase      Protein kinase domain
    5.8e-17   61.8   0.0    2.1e-16   60.0   0.0    1.7  1  Pkinase_Tyr  Protein tyrosine kinase
     0.0037   16.6   0.0     0.0075   15.6   0.0    1.5  1  Kinase-like  Kinase-like
     0.0062   15.9   0.0      0.018   14.4   0.0    1.7  2  Kdo          Lipopolysaccharide kinase (Kdo/WaaP) family


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.7   0.0     9e-22     4e-18      43     212 ..      44     217 ..      34     261 .. 0.80

  Alignments for each domain:
  == domain 1  score: 65.7 bits;  conditional E-value: 9e-22
                 HHHHHHHHHHHHHS.CTTB--EEEEEEESSEEE.EEEE--TTEBHHHHHHHHSS.--HHHHH.HHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTEE CS
     Pkinase  43 kkvlrEikilkklk.hpnivrlyevfeekdely.lvleyveggeladllerkgs.lseeeak.kiakqilegleylHskgiiHrDlKpeNiLidekgel 137
                 + ++rE ++ + l  hp+i+r+++  e + +++ l le+++ g++ +++e++    ++e+++ ++a ++  gl+ylHskg+ H Dl   Ni++  +  +
  EEA18477.1  44 DIITREATVYEVLGqHPQILRFFGREEVSPNVHsLRLELAPLGNIRQYIEEHHDePPPEDIRlQMALETSLGLNYLHSKGVRHSDLSCRNIFLFPDYRV 142
                 4689*********99**********999888777****************5544477777776999****************************999** PP

                 EE-SGTTSEESSSSCSBCTTTSCGGGS-HHHHTT.SCB.SHHHHHHHHHHHHHHHHHSS-STTTSSHHHHHHHHHHT CS
     Pkinase 138 KitDFGlakelessskltsfvgtseYlAPEvlke.ney.skkvDvWslGvilyelltgkppfsgekgkekvekeldq 212
                 Ki+DFG +    s+  ++ +     Y  P+  ++ +e    k  +++lG  +ye+++ k pfsg++++e ve+ +d+
  EEA18477.1 143 KIGDFGGSVLEGSDF-AEIVSEEISYELPRRGRDfQERpVMKREIFALGSAIYEIMAWKKPFSGSSDDE-VEASYDR 217
                 ******987655544.777777889*****9955333347899********************887776.4444444 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.0   0.0   4.7e-20   2.1e-16      48     247 ..      46     241 ..      33     248 .. 0.79

  Alignments for each domain:
  == domain 1  score: 60.0 bits;  conditional E-value: 4.7e-20
                  HHHHHHHHHTS.-BTTB--EEEEEE.SSSSEEEEEE--TTEBHHHHHHHTCTTTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEETTEEE CS
  Pkinase_Tyr  48 lleeakimkkl.khpnivkllgvct.keepllivteyvkgGdLlkfLrkkekekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsenkvvk 143
                  +++ea++ + l +hp+i+++ g    + + + + +e+++ G+++++++++++e+   +  l++al+ + G++yL+sk + H dl++rN++l  +  vk
   EEA18477.1  46 ITREATVYEVLgQHPQILRFFGREEvSPNVHSLRLELAPLGNIRQYIEEHHDEPPPEDIRLQMALETSLGLNYLHSKGVRHSDLSCRNIFLFPDYRVK 143
                  56799999999***********999556668999****************999999999*************************************** PP

                  E-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSEEEHHHHHHHHHHHHHHHHTTSSGTTTTSHHHHHHHHHHTTEES-BBTTSBHHHHHHHHHH CS
  Pkinase_Tyr 144 isDfGLardiekddeyvkkeeaklpvkWmapEslkekkftsksDvWsfGvllwEiftlgespypglkneevleklkegkrlekpekcpeelyelmkkc 241
                  i+DfG +    +d    ++e  +++++       ++++   k  +++ G  ++Ei+   ++p++g ++ ev + ++ ++  ++ +     +++++++c
   EEA18477.1 144 IGDFGGSVLEGSDFAEIVSE--EISYELPRRGRDFQERPVMKREIFALGSAIYEIMA-WKKPFSGSSDDEVEASYD-REVFPCLR--GILIATVIQDC 235
                  *****887664444444444..44444333344445556677789999999999998.789999999888665553.34444444..56688888888 PP

                  T-SSGG CS
  Pkinase_Tyr 242 weedpe 247
                  w+e+ e
   EEA18477.1 236 WDERYE 241
                  887765 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   1.7e-06    0.0075     158     254 ..     117     207 ..      84     228 .. 0.73

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 1.7e-06
  Kinase-like 158 anLqakglvhgkftvdnllldekgglmlggftaLvragtkvvl.sevekgfaPpEllgsrgg.ytrknktkmthkldaWqlGlviyriwclklPltla 253
                   +L++kg+ h +++ +n++l ++ ++++g+f+  v  g       + e ++   El   rg+ +++    +  +k +  +lG +iy i + k P+   
   EEA18477.1 117 NYLHSKGVRHSDLSCRNIFLFPDYRVKIGDFGGSVLEGSDFAEiVSEEISY---ELPR-RGRdFQE----RPVMKREIFALGSAIYEIMAWKKPFSGS 206
                  79*****************************99888888766212333344...3333.3442333....4556777788888888888888887665 PP

  Kinase-like 254 t 254
                   
   EEA18477.1 207 S 207
                  4 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.0   4.1e-06     0.018      98     153 ..      81     138 ..      71     148 .. 0.90
   2 ?   -2.2   0.0      0.48   2.2e+03      36      61 ..     223     248 ..     209     253 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 4.1e-06
         Kdo  98 rlegaqdLedllakwae..laeelkrallkavgrliaklhragvnHadlyaknillqq 153
                 +l++  ++ ++++++++  ++e  + ++  ++    + lh+ gv H dl  +ni+l  
  EEA18477.1  81 ELAPLGNIRQYIEEHHDepPPEDIRLQMALETSLGLNYLHSKGVRHSDLSCRNIFLFP 138
                 5788888999999999999999999999999************************965 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.48
         Kdo  36 yrggllgklskdlyrfklgrtravrE 61 
                  rg l++ +++d +  + ++t+ v E
  EEA18477.1 223 LRGILIATVIQDCWDERYENTGQVIE 248
                 58999999999999888999988777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (263 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       362  (0.0201908); expected 358.6 (0.02)
Passed bias filter:                      345  (0.0192426); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 1794.82
//
Query:       EEA18478.1  [L=110]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (110 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       483  (0.0269396); expected 358.6 (0.02)
Passed bias filter:                      387  (0.0215851); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.34u 0.23s 00:00:00.57 Elapsed: 00:00:00.36
# Mc/sec: 905.80
//
Query:       EEA18479.1  [L=245]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
        0.1   11.9   0.0       0.15   11.3   0.0    1.2  1  LCIB_C_CA  Limiting CO2-inducible proteins B/C beta carbonyic


Domain annotation for each model (and alignments):
>> LCIB_C_CA  Limiting CO2-inducible proteins B/C beta carbonyic anhydrases
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   8.6e-06      0.15      80     196 ..       5     127 ..       3     138 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 8.6e-06
                 EEEEEEEEEEEB-TT--BTB---TT-S---BTTHHHHHHHHHHH---------------......TTTHHHHHHHHHHGGGHHHHHH-SSHHHHHHHHH CS
   LCIB_C_CA  80 klvilagPHigiskeGeiGkvsReGrekeskaCGAlvaalkelkkeglekeskepgald......elDaeqsiikqrllkrleeiekaeddlveltkva 172
                 +++++   Hig s++ ++ ++ R   e+    C  +v+al++  + +  +++ + +++d      +  aeq  i+qrl  +++++ k + d ++ +  a
  EEA18479.1   5 HVLLYTDDHIGFSWKDDLSRLTRTQLESLLIECRHAVTALEAETDRRQLNRTPAISTVDfcwrklQKKAEQFQIRQRLDDNAKKQIKIAIDTLHTSDNA 103
                 57889999********************9999999999998833333333333445555999999999***************77788888889999** PP

                 HHHHHHHHHHHHHHTGGS-TT--E CS
   LCIB_C_CA 173 yeaikddlekliekttvdekkaev 196
                  +  ++ l+++++  t  +   e+
  EEA18479.1 104 SRKYREFLQDILHDITLRPCGPEF 127
                 **********99986655555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (245 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       907  (0.0505884); expected 358.6 (0.02)
Passed bias filter:                      599  (0.0334096); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.30s 00:00:00.82 Elapsed: 00:00:00.50
# Mc/sec: 1487.61
//
Query:       EEA18480.1  [L=201]
Description: hypothetical protein PMAA_102570 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (201 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       265  (0.0147805); expected 358.6 (0.02)
Passed bias filter:                      263  (0.014669); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.25s 00:00:00.63 Elapsed: 00:00:00.41
# Mc/sec: 1465.86
//
Query:       EEA18481.1  [L=183]
Description: hypothetical protein PMAA_102580 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (183 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       287  (0.0160076); expected 358.6 (0.02)
Passed bias filter:                      257  (0.0143343); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.39u 0.23s 00:00:00.62 Elapsed: 00:00:00.40
# Mc/sec: 1373.92
//
Query:       EEA18482.1  [L=157]
Description: hypothetical protein PMAA_102590 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (157 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       363  (0.0202465); expected 358.6 (0.02)
Passed bias filter:                      338  (0.0188521); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.45
# Mc/sec: 1052.48
//
Query:       EEA18483.1  [L=510]
Description: mitochondrial chaperone bcs1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.4e-27   94.4   0.3    1.6e-26   93.4   0.3    1.4  1  BCS1_N        BCS1 N terminal
    4.2e-17   62.8   0.0    7.5e-17   62.0   0.0    1.4  1  AAA           ATPase family associated with various cellular 
  ------ inclusion threshold ------
      0.035   14.6   0.8       0.15   12.6   0.3    2.4  2  AAA_18        AAA domain
      0.089   13.2   0.0       0.17   12.3   0.0    1.5  1  RNA_helicase  RNA helicase
      0.097   12.4   0.0        0.2   11.4   0.0    1.4  1  RuvB_N        Holliday junction DNA helicase RuvB P-loop doma
       0.11   11.3   0.0       0.19   10.6   0.0    1.2  1  PPV_E1_C      Papillomavirus helicase
       0.13   12.3   0.1       0.54   10.2   0.1    2.1  1  AAA_5         AAA domain (dynein-related subfamily)


Domain annotation for each model (and alignments):
>> BCS1_N  BCS1 N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.4   0.3   6.3e-30   1.6e-26      12     187 .]      63     236 ..      52     236 .. 0.83

  Alignments for each domain:
  == domain 1  score: 93.4 bits;  conditional E-value: 6.3e-30
      BCS1_N  12 lselaslirrrflvsveissdDeaydwvlaWlsaqpasrrsrelsvetrtksrssdssaeedededeee...dg....kkkkplrylPavgtthlfryk 103
                   +l ++++++f++s+ei+ +D+a++ + +Wl++  + + s +  ++t ++  +++++++ +e+    +   ++     +  +l ++Pa g +h+f+ +
  EEA18483.1  63 PPKLGTMLENWFMSSIEIQWTDNAFESLEDWLGQDWVCKMSTHRLATTGSRLPWNKNESDGHEE----HvleSTpprtCTLPRLTLTPANG-RHWFTIE 156
                 55677899*********************************99999999998885554433222....233311444445789********.6****** PP

      BCS1_N 104 grllavtRereekssdsetgapeetltltclgrsreilkeLleearelalkkqegktviyraa.agsggeWrrvasRpkRplstV 187
                 ++l+++ Re++e     ++g+   +l+l+c+g++  il+++l+ ar ++ + +e+kt +y+a+ ++++  W+r++ + +R+ stV
  EEA18483.1 157 RHLILLIREEKE----DAWGR-SRSLHLKCFGWDGFILRKILHAARLRHAELDENKTAVYHARfNQKSIGWTRTSGQGIRDVSTV 236
                 *********943....34554.899************************************999999*****************9 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.0   0.0   2.9e-20   7.5e-17       2     131 ..     274     398 ..     273     399 .. 0.89

  Alignments for each domain:
  == domain 1  score: 62.0 bits;  conditional E-value: 2.9e-20
                 EEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHH.....TTCCCHHHHHHHHHHHHHHHH CS
         AAA   2 llyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksr.....sgseseeeervvnqLlteldg 95 
                 l+ GppGtGKT+l+ a+a  ++ +++ +++ ++           +++l++++ e+   +il+++++d+   ++      +++++++  +++ Ll+++dg
  EEA18483.1 274 LFEGPPGTGKTSLCIALAGLFKLKIYILNLNSIS-------DGVLHDLMSSLPEQ---CILLLEDVDSQKITNlrtaePDNSTTNQPLTLSGLLNAIDG 362
                 899******************************9.......88889999887543...*********97666676776566777777899********* PP

                 TTTSSSTEEEEEEESSGGGSTHHHHS.TTSSEEEETT CS
         AAA  96 vkkkeskvivigatnrpdkldpallr.gRfdrkieie 131
                 v+ +e+  i+i++tn+ dkld+al r gR+d+ i +e
  EEA18483.1 363 VTASEG-RILIMTTNHRDKLDDALTRpGRVDMTISFE 398
                 ***977.9************************99886 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0      0.89   2.3e+03      27      70 ..     178     229 ..     158     251 .. 0.67
   2 ?   12.6   0.3     6e-05      0.15       3      25 ..     275     305 ..     274     436 .. 0.73

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.89
      AAA_18  27 nlrdvakenglllevdpealdeskrldedkldklldaleenss........a 70 
                 +l++  +++ +l    ++a  ++ +lde+k+++ +  +++ s          
  EEA18483.1 178 HLKCFGWDGFILRKILHAARLRHAELDENKTAVYHARFNQKSIgwtrtsgqG 229
                 5566666666666666667778889999999999999998876674433332 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 6e-05
      AAA_18   3 ltGtpGvGKttlakeLskrlgf........g 25 
                   G+pG+GKt+l+ +L+ + ++        +
  EEA18483.1 275 FEGPPGTGKTSLCIALAGLFKLkiyilnlnS 305
                 57**************877544555444330 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   6.7e-05      0.17       2     106 ..     274     376 ..     273     377 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 6.7e-05
  RNA_helicase   2 wlyGpsgeGKStlakeLakallkklklkkkdsvysrnpeddfwdgYtgqevvvidDfgqvkdeenps.dlaelirlvsstpyplnmasleekg.tlf 96 
                   ++ Gp+g+GK++l+  La  +  k+   + +s +s ++ +d +++  +q +++ +D+ ++k +   +   ae  +  +++p++l     +  g t  
    EEA18483.1 274 LFEGPPGTGKTSLCIALAGLFKLKIYILNLNS-ISDGVLHDLMSSLPEQCILLLEDVDSQKIT---NlRTAEPDNSTTNQPLTLSGLLNAIDGvTAS 366
                   578******************99996666555.599*********************999977...6688888888888888888766666666777 PP

  RNA_helicase  97 tSkvvivtsN 106
                   + +++i+t+N
    EEA18483.1 367 EGRILIMTTN 376
                   8888888888 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   7.6e-05       0.2      36      93 ..     273     329 ..     257     336 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 7.6e-05
      RuvB_N  36 vllyGpPGlGkttlakiiakelgvklkitsgPvlekagdlaalltnleekdvlfidei 93 
                  l+ GpPG Gkt+l+  +a  ++ k+ i     ++  g l  l+++l e+ +l+++++
  EEA18483.1 273 YLFEGPPGTGKTSLCIALAGLFKLKIYILNLNSIS-DGVLHDLMSSLPEQCILLLEDV 329
                 5899***************9999999988887775.5778888888888888877766 PP

>> PPV_E1_C  Papillomavirus helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   7.2e-05      0.19     251     305 ..     259     314 ..     245     337 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 7.2e-05
    PPV_E1_C 251 alkefLkgvPkknclvllGppntGkslfamslikfLkGkv.lsfvnskshfWlqPL 305
                 +l +  +g+P ++  ++ Gpp tGk+ ++ +l  ++k k+ +   ns s+  l  L
  EEA18483.1 259 KLWHNQRGIPYRQGYLFEGPPGTGKTSLCIALAGLFKLKIyILNLNSISDGVLHDL 314
                 56666799*************************99998874455677775444433 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.1   0.00021      0.54       3      33 ..     274     304 ..     272     387 .. 0.95

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00021
                 EEE--SSSSHHHHHHHGGGGBS--EEEEE-- CS
       AAA_5   3 lLvGppGtgKselaerlaaalnreveyvqlt 33 
                 l  GppGtgK++l   la +++ ++ + +l+
  EEA18483.1 274 LFEGPPGTGKTSLCIALAGLFKLKIYILNLN 304
                 678**************99998888877766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (510 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       958  (0.053433); expected 358.6 (0.02)
Passed bias filter:                      760  (0.0423894); expected 358.6 (0.02)
Passed Vit filter:                        91  (0.00507558); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.66u 0.33s 00:00:00.99 Elapsed: 00:00:00.50
# Mc/sec: 3038.18
//
Query:       EEA18484.1  [L=288]
Description: hypothetical protein PMAA_102610 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (288 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       351  (0.0195772); expected 358.6 (0.02)
Passed bias filter:                      306  (0.0170673); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.32s 00:00:00.81 Elapsed: 00:00:00.50
# Mc/sec: 1748.44
//
Query:       EEA18485.1  [L=496]
Description: hypothetical protein PMAA_102620 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
     0.0096   16.7   0.9     0.0096   16.7   0.9    4.0  5  zf-C2H2_4  C2H2-type zinc finger
  ------ inclusion threshold ------
      0.034   14.1   0.5        0.1   12.6   0.5    1.9  1  zf-C2HC_2  zinc-finger of a C2HC-type
      0.044   14.1   0.0      0.044   14.1   0.0    2.7  3  zf-Di19    Drought induced 19 protein (Di19), zinc-binding
      0.076   13.5   1.3      0.076   13.5   1.3    2.6  2  zf-C2H2    Zinc finger, C2H2 type


Domain annotation for each model (and alignments):
>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.2         4   1.8e+04       2      12 ..      18      28 ..      17      30 .. 0.68
   2 !   16.7   0.9   2.1e-06    0.0096       2      22 ..      44      64 ..      43      66 .. 0.93
   3 ?   -2.4   0.7         3   1.4e+04       1      16 [.     255     261 ..     252     263 .. 0.52
   4 ?   -2.1   0.1       2.4   1.1e+04       5      13 ..     401     409 ..     400     413 .. 0.78
   5 ?    0.7   0.1       0.3   1.3e+03      15      24 .]     473     482 ..     463     482 .. 0.67

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 4
   zf-C2H2_4  2 kCpiCgksFss 12
                 Cp+ ++++ +
  EEA18485.1 18 HCPLHREVYET 28
                58877777765 PP

  == domain 2  score: 16.7 bits;  conditional E-value: 2.1e-06
   zf-C2H2_4  2 kCpiCgksFsskkaLlrHlkt 22
                 Cp+Cgks s+ ++L++Hlkt
  EEA18485.1 44 NCPYCGKSHSNASRLRKHLKT 64
                5******************98 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 3
   zf-C2H2_4   1 fkCpiCgksFsskkaL 16 
                 f+Cp+         +L
  EEA18485.1 255 FRCPY---------DL 261
                 45554.........44 PP

  == domain 4  score: -2.1 bits;  conditional E-value: 2.4
   zf-C2H2_4   5 iCgksFssk 13 
                 +C ++F ++
  EEA18485.1 401 VCYEWFERC 409
                 799***876 PP

  == domain 5  score: 0.7 bits;  conditional E-value: 0.3
   zf-C2H2_4  15 aLlrHlkthH 24 
                 +L++H+ ++H
  EEA18485.1 473 TLRQHVFAVH 482
                 47****9999 PP

>> zf-C2HC_2  zinc-finger of a C2HC-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.5   2.2e-05       0.1       5      22 ..      45      63 ..      42      64 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 2.2e-05
   zf-C2HC_2  5 CpkCgRsF.npdrlekHep 22
                Cp+Cg s  n++rl kH +
  EEA18485.1 45 CPYCGKSHsNASRLRKHLK 63
                *****************87 PP

>> zf-Di19  Drought induced 19 protein (Di19), zinc-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   9.8e-06     0.044       4      23 ..      44      64 ..      42      74 .. 0.84
   2 ?   -2.6   0.3       1.5   6.9e+03       3       7 ..     255     259 ..     254     264 .. 0.85
   3 ?   -0.1   0.2      0.25   1.1e+03       5      25 ..     463     482 ..     448     485 .. 0.54

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 9.8e-06
     zf-Di19  4 tCPyCgk.eltvkeLveHved 23
                +CPyCgk + ++++L +H+++
  EEA18485.1 44 NCPYCGKsHSNASRLRKHLKT 64
                6******7788999****987 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.5
     zf-Di19   3 ftCPy 7  
                 f CPy
  EEA18485.1 255 FRCPY 259
                 89**9 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.25
     zf-Di19   5 CPyCgkeltvkeLveHvedeH 25 
                 CP Cg+e +  +L +Hv + H
  EEA18485.1 463 CP-CGREEKSITLRQHVFAVH 482
                 44.444444455555554444 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   1.3   1.7e-05     0.076       3      22 ..      45      64 ..      44      64 .. 0.95
   2 ?   -3.8   0.6         4   1.8e+04       1       5 [.     255     259 ..     255     262 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 1.7e-05
                ETTTTEEESSHHHHHHHHHC CS
     zf-C2H2  3 CpdCgksFkrksnLkrHirt 22
                Cp+Cgks ++ s L++H++t
  EEA18485.1 45 CPYCGKSHSNASRLRKHLKT 64
                *****************986 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 4
                 EEETT CS
     zf-C2H2   1 ykCpd 5  
                 ++Cp+
  EEA18485.1 255 FRCPY 259
                 89993 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (496 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       613  (0.0341904); expected 358.6 (0.02)
Passed bias filter:                      468  (0.026103); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.60u 0.33s 00:00:00.93 Elapsed: 00:00:00.50
# Mc/sec: 2969.52
//
Query:       EEA18486.1  [L=787]
Description: hypothetical protein PMAA_102630 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.1e-05   24.6   0.0    2.1e-05   24.6   0.0    2.9  3  APH             Phosphotransferase enzyme family
    0.00011   21.9   1.4    0.00039   20.1   0.0    2.3  3  Choline_kinase  Choline/ethanolamine kinase
     0.0011   17.9   0.0      0.013   14.4   0.0    2.1  1  Otopetrin       Otopetrin
  ------ inclusion threshold ------
      0.017   15.1   0.0        1.3    9.1   0.0    2.6  2  HSDR_N_2        Type I restriction enzyme R protein N terminu
       0.02   14.3   0.0      0.042   13.2   0.0    1.5  1  Pkinase         Protein kinase domain
       0.15   11.7   0.0       0.25   10.9   0.0    1.2  1  WaaY            Lipopolysaccharide core biosynthesis protein 
       0.87    9.4  17.4        0.7    9.8  11.6    2.3  2  eIF3_subunit    Translation initiation factor eIF3 subunit
        2.6    5.9   5.4        3.6    5.4   5.4    1.2  1  V_ATPase_I      V-type ATPase 116kDa subunit family
        5.2    7.2   8.1        7.5    6.7   5.5    2.3  2  CPSF100_C       Cleavage and polyadenylation factor 2 C-termi
        6.7    6.0  14.9         14    5.0  14.9    1.5  1  GBP_C           Guanylate-binding protein, C-terminal domain
        9.1    6.7   6.7         62    4.0   0.1    2.7  2  RNA_pol_Rpc4    RNA polymerase III RPC4


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   6.4       1.6   2.6e+03     115     159 ..      25      69 ..       6      90 .. 0.62
   2 ?   -2.4   0.0       2.2   3.6e+03      62     142 ..     363     438 ..     358     450 .. 0.60
   3 !   24.6   0.0   1.3e-08   2.1e-05     140     199 ..     690     742 ..     669     745 .. 0.72

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 1.6
                 B-SHHCHTCCHHHHHHCHHHCCCGCCTCCHHHHHHHHHHHHHHHH CS
         APH 115 ladflaqdlellrqlesatarllaselldlleeleeqvlaalaal 159
                  +++++q++++++q+ ++  +++++e ++++ee+e+++  +++++
  EEA18486.1  25 RRREEEQRRREEEQRRREEEQQRREEEQQRREEAERNLNLERLQT 69 
                 345555666666666666667777777778888888744333333 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 2.2
                 S-EEETTEEEEEEE----EE-SSHHHHHHHHHHHHHHHHHHC.CHHCH.-STTTB-SHHCHTCCHHHHHHCHHHCCCGCCTC CS
         APH  62 tddeeigllfalieyvpgrsllrklsaaqlpellealgefla.alhqvdpaalpladflaqdlellrqlesatarllasell 142
                 t  +++++l++ +e v+ ++ +  +  ++ +  l a+g++la  l ++    +  +++ a++ +   qle +    +  +ll
  EEA18486.1 363 TPSTVLYYLSVPHEDVGNTTGWYGDAKNDNRLHLTAVGQLLAfTLRSL----RTSPRDIAWRNWARSQLETW--EMVYDDLL 438
                 566667777777777777777775555666666666666666444455....45555555666666666666..44444444 PP

  == domain 3  score: 24.6 bits;  conditional E-value: 1.3e-08
                 CTCCHHHHHHHHHHHHHHHH--SSS-EEEE-SS-SGGGEEEC..TTEEEEE---TT-EEE CS
         APH 140 elldlleeleeqvlaalaallpgelptvllHgDlhpgNllvdpddgrvtGviDfedaglg 199
                 ++++  ++l +q +++ ++  +     ++lH D+ pgN++++++++rv  +iDfe+a++ 
  EEA18486.1 690 DFDE--AQLIAQ-AETSLRAIH---NLGVLHSDPIPGNMIWNEEGQRV-MFIDFERARYQ 742
                 3333..444443.444455555...799**************888888.9*******986 PP

>> Choline_kinase  Choline/ethanolamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.7       4.5   7.3e+03     104     140 ..      44      80 ..      28      87 .. 0.59
   2 ?   -0.5   0.0      0.48   7.9e+02      30      84 ..     138     194 ..     125     238 .. 0.74
   3 !   20.1   0.0   2.4e-07   0.00039     144     179 ..     709     744 ..     685     745 .. 0.83

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 4.5
                     CS.TT..ECHHGGCCHCCCTHHHHHHHHHTHHHHHHC CS
  Choline_kinase 104 keaqtkakkekkkkqlklinledlekeleklekllee 140
                     ++++++++++ +++  + +nle+l+   ++l ++l+ 
      EEA18486.1  44 EQQRREEEQQRREEAERNLNLERLQTRNTTLPEFLDA 80 
                     3334444444455555566777777766666666654 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.48
                     HHHTTSSS-EEEEETTEEEEE--TCEE--TTGGGCHHHHHHHHHHHHHHTTCHH... CS
  Choline_kinase  30 lserglgpklygifenGrieefiesrtlstedlrepeiskkiAkklaelHslel..e 84 
                     + er++ p l    ++  i + +++++l+   ++ +++ +++A+ ++el ++ +   
      EEA18486.1 138 VTERRFTPLLALKESGREIMKRMHGSELDIGYFQRETVESRVASVIEELYASRPlrR 194
                     667888888888888888999999999999999999999999999999988887441 PP

  == domain 3  score: 20.1 bits;  conditional E-value: 2.4e-07
                     -EEEE-S--SGGGEEE.-CTTEEEE--GTT-EEEEH CS
  Choline_kinase 144 pvvfcHnDlqegNillnkeekklvlIDFEYagynyr 179
                     ++   H D ++gN++ n+e +++++IDFE a y  r
      EEA18486.1 709 NLGVLHSDPIPGNMIWNEEGQRVMFIDFERARYQKR 744
                     46667************************9999765 PP

>> Otopetrin  Otopetrin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.0   7.8e-06     0.013     118     196 ..      40     439 ..       9     548 .. 0.57

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 7.8e-06
   Otopetrin 118 aridalrkakkvl..............................................tkstakekiisarleqrtastesqs............... 155
                 +r+++++++++ +                                              t                       +               
  EEA18486.1  40 RREEEQQRREEEQqrreeaernlnlerlqtrnttlpefldachkhlflgltiqkdkkssT-----------------------Kgdpanadrklrpsri 115
                 111111111222211122223333444444444444444444444444444444444440.......................0444444444444444 PP

   Otopetrin 156 ................................................................................................... 155
                                                                                                                    
  EEA18486.1 116 qewtdfpdeqmaiwadlmdadfvterrftpllalkesgreimkrmhgseldigyfqretvesrvasvieelyasrplrrkfnlrgnvtfenhantltde 214
                 445555555555555555555555555555555555555555555555555555555555555555555555555555555555555555555555555 PP

   Otopetrin 156 ................................................................................................... 155
                                                                                                                    
  EEA18486.1 215 srivtdmsylrleqegprrserlagrsrdtsrstsrarrqtaaqsrrprpradqfcvynrgpdenipsflieykaphklslahikaglqdmeldrivry 313
                 555555555666666666666666666666666666666666677788888899999999999999999999999999999999999999999999999 PP

   Otopetrin 156 ......lieCertnimgtlvqdaapylyPfiiEYsligaavlyvmw..................................................... 195
                          C+rt  +  +v+++++y+y   iEY ++  ++ +++                                                      
  EEA18486.1 314 qerespEDICRRT--IAAVVTQLSDYMYASGIEYGCMTTGEAFIFLrvphhtpstvlyylsvphedvgnttgwygdakndnrlhltavgqllaftlrsl 410
                 999998899*998..788*************************99855656666555555555555555555555555555555555555555555555 PP

   Otopetrin 196 ............................k 196
                                              
  EEA18486.1 411 rtsprdiawrnwarsqletwemvyddllD 439
                 55555555555555555555555555550 PP

>> HSDR_N_2  Type I restriction enzyme R protein N terminus (HSDR_N)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.0     0.059        97      30      60 ..     257     291 ..     247     314 .. 0.75
   2 ?    9.1   0.0   0.00077       1.3      66      98 ..     329     361 ..     323     372 .. 0.87

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.059
    HSDR_N_2  30 lqlgskkkraD.ivvykkd...kkpllivecKaps 60 
                  q+ + ++raD ++vy++    + p  ++e+Kap+
  EEA18486.1 257 AQSRRPRPRADqFCVYNRGpdeNIPSFLIEYKAPH 291
                 455577888984578887765444*********98 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.00077
    HSDR_N_2  66 evleqlksYlealkaeylvvtNglehivykvdk 98 
                 +v+ ql+ Y+ a ++ey+ +t g+ +i+++v  
  EEA18486.1 329 AVVTQLSDYMYASGIEYGCMTTGEAFIFLRVPH 361
                 5789************************99755 PP

>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   2.6e-05     0.042     101     149 ..     694     743 ..     670     763 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 2.6e-05
                 HHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTE.EEE-SGTTSEESS CS
     Pkinase 101 kkiakqilegleylHskgiiHrDlKpeNiLidekge.lKitDFGlakele 149
                  ++++q  ++l+ +H+ g++H D  p N++ +e+g+ ++ +DF  a+  +
  EEA18486.1 694 AQLIAQAETSLRAIHNLGVLHSDPIPGNMIWNEEGQrVMFIDFERARYQK 743
                 4567788899**********************88888******9998766 PP

>> WaaY  Lipopolysaccharide core biosynthesis protein (WaaY)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00015      0.25     133     185 ..     688     741 ..     662     746 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00015
        WaaY 133 mpeidd.evkakikqsieklhqlgmvsgdphrgnfivkkdevriidlsgkrasa 185
                   + d+ ++ a+ ++s++++h+lg++  dp  gn+i ++++ r++ +   ra  
  EEA18486.1 688 QHDFDEaQLIAQAETSLRAIHNLGVLHSDPIPGNMIWNEEGQRVMFIDFERARY 741
                 555554247789999************************999987666666555 PP

>> eIF3_subunit  Translation initiation factor eIF3 subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8  11.6   0.00043       0.7      70     125 ..      17      88 ..      10     126 .. 0.66
   2 ?    2.6   0.3     0.066   1.1e+02      29      77 ..     489     534 ..     477     551 .. 0.56

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00043
  eIF3_subunit  70 kqkiaekeerrkaeeeeaeeeeeleeedeaarkerlrkaeeesDlknaadlFGgv.................a 125
                   +++i e++ rr++ee++ +eee+   e+e++r+e+++++ ee++ ++  + + +                   
    EEA18486.1  17 ENQIREEQ-RRREEEQRRREEEQRRREEEQQRREEEQQRREEAERNLNLERLQTRnttlpefldachkhlflG 88 
                   45566666.6677777788888889999999999999999999988877766644555555555555555550 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.066
  eIF3_subunit  29 ededvkdswdaeeeeeeekekakkaaeakakaakakkkkskkqkiaeke 77 
                    ++d  ds d +  + +++++   + +a   +a++++k +k+q+ + k 
    EEA18486.1 489 HEDDADDSLDPSTPSRAPRDSRFPQRQA---TAATTRKSTKSQQSNSKG 534
                   4445566666666666666555222222...334444444444444443 PP

>> V_ATPase_I  V-type ATPase 116kDa subunit family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   5.4    0.0022       3.6      32     119 ..       6      90 ..       2     193 .. 0.71

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.0022
  V_ATPase_I  32 cdemerklrfleeeieklekavikeeeaeesleapeekeldeleeelekleeelkelnenleklkkelnelvelkavlekakefleee 119
                 +d++ r+lr  e++i++++    +e++  +++e+++++e ++  +e e+  +e  e n nle+l+++ ++l e    ++k   fl  +
  EEA18486.1   6 IDDLRRRLRHAENQIREEQRRREEEQR--RREEEQRRREEEQQRREEEQQRREEAERNLNLERLQTRNTTLPEFLDACHKH-LFLGLT 90 
                 899999999999999995554444444..4444444444444455555555555677788888888888888887777553.344444 PP

>> CPSF100_C  Cleavage and polyadenylation factor 2 C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   5.5    0.0046       7.5      41     107 ..      21      88 ..       3      99 .. 0.57
   2 ?   -0.0   0.0      0.55   8.9e+02      68      78 ..     521     531 ..     477     625 .. 0.56

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0046
   CPSF100_C  41 ekeeeeeeeeeeeeeeeaskkqklaeksekeaseeeseekkeslptldvlpankas.vrsaaqplfvG 107
                  +e++++eee++ +eee+++++++++ +e+e++++e++e++ +l +l++ ++++ + +   ++ lf G
  EEA18486.1  21 REEQRRREEEQRRREEEQRRREEEQQRREEEQQRREEAERNLNLERLQTRNTTLPEfLDACHKHLFLG 88 
                 22222222233333333333333345556666666666677777777777777777666677777776 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 0.55
   CPSF100_C  68 sekeaseeese 78 
                 + k++++++s+
  EEA18486.1 521 TRKSTKSQQSN 531
                 11111111111 PP

>> GBP_C  Guanylate-binding protein, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0  14.9    0.0084        14     195     257 ..       9      71 ..       2      98 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0084
       GBP_C 195 tdkaltakekeieaeqakaeaaeaekelleekqkeeeqrmeakeksleehvkqLk.ekleeere 257
                 + + l ++e +i++eq ++e+ ++ +e+ + +++ee+qr e+++++ ee  ++L+ e+l+ +r+
  EEA18486.1   9 LRRRLRHAENQIREEQRRREEEQRRREEEQRRREEEQQRREEEQQRREEAERNLNlERLQ-TRN 71 
                 56789999*********9999999999999999999999999999999999999734444.444 PP

>> RNA_pol_Rpc4  RNA polymerase III RPC4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   3.1     0.067   1.1e+02      37      75 ..      23      61 ..       8      79 .. 0.40
   2 ?    4.0   0.1     0.038        62      25      75 ..     488     538 ..     352     551 .. 0.60

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.067
  RNA_pol_Rpc4 37 ekakaeeeskaekasgaeaeekkskkksskkkkkkkska 75
                  e+++ eee++  ++++   ee+++ ++++++ +++++ +
    EEA18486.1 23 EQRRREEEQRRREEEQRRREEEQQRREEEQQRREEAERN 61
                  222222222222222222222222222222233333333 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.038
  RNA_pol_Rpc4  25 eddkseaesqsaekakaeeeskaekasgaeaeekkskkksskkkkkkkska 75 
                   ++++++++s + ++ + +++++   + +a+a+++++++ks+++++k+ks +
    EEA18486.1 488 DHEDDADDSLDPSTPSRAPRDSRFPQRQATAATTRKSTKSQQSNSKGKSRK 538
                   333333333333344444444444444444444444444444444444433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (787 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2127  (0.118635); expected 358.6 (0.02)
Passed bias filter:                      855  (0.0476881); expected 358.6 (0.02)
Passed Vit filter:                       228  (0.0127168); expected 17.9 (0.001)
Passed Fwd filter:                        44  (0.00245412); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.87u 0.32s 00:00:01.19 Elapsed: 00:00:00.58
# Mc/sec: 4085.67
//
Query:       EEA18487.1  [L=275]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.4e-13   49.0   0.0    1.6e-12   47.9   0.0    1.6  1  APH             Phosphotransferase enzyme family
    7.2e-10   38.8   0.0    1.8e-09   37.5   0.0    1.7  1  Choline_kinase  Choline/ethanolamine kinase


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.9   0.0   1.7e-16   1.6e-12      45     229 ..      64     240 ..      34     264 .. 0.76

  Alignments for each domain:
  == domain 1  score: 47.9 bits;  conditional E-value: 1.7e-16
                 HHHHHTT-.B--B-CTTBS-EEETTEEEEEEE----EE-SSHHHHHHHHHHHHHHHHHHCCHHCH..-STTTB-SHHCHTCCHHHHHHCHHH.CCCGCC CS
         APH  45 rlLakagv.pvPevlagdtddeeigllfalieyvpgrsllrklsaaqlpellealgeflaalhqvd.paalpladflaqdlellrqlesata.rllase 140
                 ++++ +++ +vP+v+ +   ++e+g+ f+++ yvpg+ l++ l+  +  +++ ++   +a+l q+  +++ ++ ++  ++ +l+ +    ++  ++a++
  EEA18487.1  64 KNVN-HNIvRVPRVYRF--VQDELGRGFLFMDYVPGQKLSD-LDLTVHTDIIPRITNIIAHLGQIKhGQKPGPIGEKGPQGYLWGDDGVDKPfVSVAHL 158
                 3333.33469******8..77777777**************.888889999999999999999998555556666665556655555555555666666 PP

                 TCCHHHHHHHHHHHHHHHH--SSS-EEEE-SS-SGGGEEEC..TTEEEEE---TT-EEEECCHHHHCCHHHCSCHCCCHCHHHHHHHHC CS
         APH 141 lldlleeleeqvlaalaallpgelptvllHgDlhpgNllvdpddgrvtGviDfedaglgpplyDlavllrswtseldpeflaallraye 229
                 ++  l ++ + +++   +l p   p vl+H Dl  +N+++  +d + ++++D+  ag  p+ y+la l+  ++s+ d+ + + l++a e
  EEA18487.1 159 NRY-LNRRLS-LRNDSIDLSP--YPLVLCHMDLVRRNMILG-EDKKSIYLLDWAHAGFFPRFYELAALP--CMSPYDEPYEKPLIAATE 240
                 666.666666.8888888888..9*****************.555556********************9..567788777777777766 PP

>> Choline_kinase  Choline/ethanolamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.5   0.0     2e-13   1.8e-09     123     201 ..     157     236 ..      84     248 .. 0.77

  Alignments for each domain:
  == domain 1  score: 37.5 bits;  conditional E-value: 2e-13
                     THHHHHHHHHTHH.HHHHCHGG-EEEE-S--SGGGEEE.-CTTEEEE--GTT-EEEEHHHHHHHHHHHTTEEHHHCSTSH CS
  Choline_kinase 123 nledlekelekle.klleelespvvfcHnDlqegNillnkeekklvlIDFEYagynyrgfDlanhfiEwagdyeeeeaff 201
                     +l+++ +   +l+   ++ + +p+v+cH Dl+ +N++l +++k+++l D+  ag+ +r ++la   +   +d+ +e++ +
      EEA18487.1 157 HLNRYLNRRLSLRnDSIDLSPYPLVLCHMDLVRRNMILGEDKKSIYLLDWAHAGFFPRFYELAALPCMSPYDEPYEKPLI 236
                     44544444334430445788999*****************************************9999999888887744 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       265  (0.0147805); expected 358.6 (0.02)
Passed bias filter:                      257  (0.0143343); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.37u 0.24s 00:00:00.61 Elapsed: 00:00:00.41
# Mc/sec: 2024.42
//
Query:       EEA18488.1  [L=1558]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      7e-82  269.9  33.2    9.9e-17   61.1   1.0    6.8  6  HEAT_2          HEAT repeats
    3.2e-55  179.4  12.6      0.012   15.8   0.0   15.8 15  HEAT            HEAT repeat
    3.2e-33  113.7  19.5      0.012   16.0   0.5   14.5 15  HEAT_EZ         HEAT-like repeat
    7.6e-17   61.7   0.0        3.7    7.4   0.0   12.3 13  DUF3385         Domain of unknown function (DUF3385)
    1.8e-16   60.1  25.2       0.58   10.5   0.0   12.8 13  Cohesin_HEAT    HEAT repeat associated with sister chromatid 
    7.4e-15   54.1  44.1        3.3    8.7   0.1   15.4 15  HEAT_PBS        PBS lyase HEAT-like repeat
    1.5e-13   51.0   0.1    2.9e-13   50.1   0.1    1.5  1  NACHT           NACHT domain
    2.8e-10   39.4   0.0    1.1e-06   27.5   0.0    3.8  2  Adaptin_N       Adaptin N terminal region
    4.6e-08   32.6   0.0    7.9e-08   31.8   0.0    1.3  1  PNP_UDP_1       Phosphorylase superfamily
    9.2e-08   32.7   0.1    3.2e-07   30.9   0.1    2.0  1  NLRC4_HD2       NLRC4 helical domain HD2
    9.3e-08   31.6   0.0    2.4e-07   30.2   0.0    1.6  1  NB-ARC          NB-ARC domain
    1.1e-06   28.7   2.7         45    4.3   0.0    9.0 10  CO_deh_flav_C   CO dehydrogenase flavoprotein C-terminal doma
    6.7e-06   26.6   1.3         12    6.6   0.0    7.9  7  Vac14_Fab1_bd   Vacuolar 14 Fab1-binding region
    0.00015   22.2   5.7      0.022   15.1   0.0    5.6  4  AAA_16          AAA ATPase domain
    0.00019   21.9   0.0        6.9    7.0   0.0    7.1  6  EPL1            Enhancer of polycomb-like
    0.00023   21.0   9.6      0.024   14.4   1.7    3.8  3  DNA_alkylation  DNA alkylation repair enzyme
    0.00035   20.5   0.0      2e+02    2.2   0.0    7.5  8  Arm             Armadillo/beta-catenin-like repeat
    0.00062   20.0   0.0     0.0027   18.0   0.0    2.1  1  AAA_22          AAA domain
     0.0012   18.7   0.0         17    5.4   0.0    6.5  7  Nore1-SARAH     Novel Ras effector 1 C-terminal SARAH (Sav/Ra
     0.0033   16.7   0.2         39    3.3   0.0    6.1  5  Cnd3            Nuclear condensing complex subunits, C-term d
  ------ inclusion threshold ------
      0.021   15.3   0.0      0.075   13.5   0.0    2.0  1  AAA             ATPase family associated with various cellula
      0.043   13.7   0.0      0.081   12.8   0.0    1.4  1  NTPase_1        NTPase
      0.054   14.1   0.0       0.23   12.0   0.0    2.2  1  AAA_18          AAA domain
       0.12   12.7   0.0       0.29   11.5   0.0    1.6  1  RNA_helicase    RNA helicase
       0.17   11.9   0.0       0.43   10.6   0.0    1.7  1  AAA_14          AAA domain
       0.19   11.6   0.0       0.42   10.5   0.0    1.5  1  ATPase_2        ATPase domain predominantly from Archaea
       0.19   12.1   0.7        2.9    8.3   0.1    3.3  3  AAA_17          AAA domain
       0.23   11.2   0.0       0.43   10.3   0.0    1.4  1  PduV-EutP       Ethanolamine utilisation - propanediol utilis


Domain annotation for each model (and alignments):
>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.6   0.1   3.9e-13   2.5e-10      11      88 .]     908     989 ..     896     989 .. 0.82
   2 !   59.0   1.0   6.9e-19   4.4e-16       1      88 []     999    1091 ..     999    1091 .. 0.91
   3 !   52.6   2.6   7.1e-17   4.6e-14       2      87 ..    1102    1193 ..    1101    1194 .. 0.88
   4 !   61.1   1.0   1.5e-19   9.9e-17       1      88 []    1204    1296 ..    1204    1296 .. 0.92
   5 !   52.7   0.1   6.7e-17   4.3e-14       4      87 ..    1309    1397 ..    1306    1398 .. 0.90
   6 !   44.7   2.4     2e-14   1.3e-11       1      87 [.    1374    1464 ..    1374    1465 .. 0.89

  Alignments for each domain:
  == domain 1  score: 40.6 bits;  conditional E-value: 3.9e-13
      HEAT_2  11 dpdpevrraairaLg.rignp.ealpaLvellededpavRraaaeaLgaig..dpealpaLkellddddddvvReaAaeaLa 88 
                   +   r++++raL+ r++    ++++ ++++ d+d++vRraa+eaLg     +p  l+a  ++l +d+d+ vR+aA++aL+
  EEA18488.1 908 QRESSCRKKILRALAyRWHMSfNLMDITTNFMGDSDSNVRRAAVEALGTQSpwSPNILEAVIRRLENDEDSGVRRAAIKALG 989
                 556668999******755544589************************776457*************************996 PP

  == domain 2  score: 59.0 bits;  conditional E-value: 6.9e-19
      HEAT_2    1 ldaLlqalendpdpevrraairaLgrig..npealpaLvell.ededpavRraaaeaLgaig..dpealpaLkellddddddvvReaAaeaLa 88  
                  l+a + +len  d ++r+aai+aLg++   +p +l+a+++ l +de+++vR++a++aLg     +p+ l+a  ++l +d+d+ vR+aA+eaL+
  EEA18488.1  999 LEAVIRQLENNRDSYIRHAAIKALGTQSswSPALLEAVIRRLeNDENSNVRYTAIKALGTQSpwSPAILEAVIRRLENDKDSGVRRAAIEALG 1091
                  578999*******************665126899********789**************777467**************************96 PP

  == domain 3  score: 52.6 bits;  conditional E-value: 7.1e-17
      HEAT_2    2 daLlqalen.dpdpevrraairaLgrig..npealpaLvell.ededpavRraaaeaLgaig..dpealpaLkellddddddvvReaAaeaL 87  
                  +a + +le+ d+ ++vr++ai aLg++   +p +l+a+++ l ++++++vRraa++aL+     +p+ l+a  ++l +d+d+ vR+aA+eaL
  EEA18488.1 1102 EAVIRRLEKnDETWDVRHTAINALGTQSpwSPALLEAVIRRLeNNTEWNVRRAAINALSTQSpwSPAILEAVIRRLENDEDSGVRRAAIEAL 1193
                  6788888555***************776236899********56799***********9776467**************************9 PP

  == domain 4  score: 61.1 bits;  conditional E-value: 1.5e-19
      HEAT_2    1 ldaLlqalendpdpevrraairaLg..rignpealpaLvell.ededpavRraaaeaLgaig..dpealpaLkellddddddvvReaAaeaLa 88  
                  l+a + +lend+ ++vrraai+aL   +  +p +l+a+++ l +de+++vR+aa+ea+g     +p+ l+a  ++l +d+d+ v++aA+eaL+
  EEA18488.1 1204 LEAVIRRLENDEKWYVRRAAIEALRtqSPCSPNILEAVIRRLeNDENSYVRYAAIEAIGTQSpwSPAILEAVIRRLENDEDSGVKRAAIEALG 1296
                  578999*******************5333789**********889**************777467**************************96 PP

  == domain 5  score: 52.7 bits;  conditional E-value: 6.7e-17
      HEAT_2    4 LlqalendpdpevrraairaLgrig..npealpaLvell.ededpavRraaaeaLgaig..dpealpaLkellddddddvvReaAaeaL 87  
                   + +lend+  ++r+aai++Lg++   +p +l+a++  l ++ed++ Rraa+eaLg+    +p+ l+a  ++l +d++++vR+aA++aL
  EEA18488.1 1309 VIRQLENDEGFYIRYAAIKTLGTQSswSPAILKAMIHQLeNNEDSDMRRAAIEALGKQSpwSPALLEAVIRRLENDEKWYVRRAAIKAL 1397
                  6899******************655126899******99667**************998566**************************9 PP

  == domain 6  score: 44.7 bits;  conditional E-value: 2e-14
      HEAT_2    1 ldaLlqalendpdpevrraairaLg..rignpealpaLvell.ededpavRraaaeaLgaig..dpealpaLkellddddddvvReaAaeaL 87  
                  l+a + +lend+ ++vrraai+aL   ++ +p++l+a++  l +ded+ vRraa++aL+     +p+ l+a  ++l +++d++v  + +eaL
  EEA18488.1 1374 LEAVIRRLENDEKWYVRRAAIKALStqSLWSPDILDAVICRLeNDEDSGVRRAAIKALSTQSlwSPAILEAVIRRLENEEDSEVASK-IEAL 1464
                  578999*******************755679***********789*************9666347******************9887.6665 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.5   0.0   0.00046       0.3       8      26 ..     938     956 ..     931     956 .. 0.84
   2 !   14.0   0.0   7.1e-05     0.046       1      26 [.     964     990 ..     964     990 .. 0.92
   3 ?    6.5   0.0     0.019        12       1      26 [.     998    1024 ..     998    1024 .. 0.87
   4 !   15.8   0.0   1.9e-05     0.012       1      26 [.    1032    1058 ..    1032    1058 .. 0.92
   5 !   13.4   0.0   0.00011     0.072       1      26 [.    1066    1092 ..    1066    1092 .. 0.92
   6 !   10.9   0.0   0.00068      0.44      10      26 ..    1111    1127 ..    1100    1127 .. 0.82
   7 !   11.2   0.1   0.00055      0.35       1      25 [.    1135    1160 ..    1135    1161 .. 0.90
   8 !   11.1   0.0   0.00061      0.39       1      24 [.    1169    1193 ..    1169    1195 .. 0.91
   9 !   14.5   0.0   4.9e-05     0.032       1      25 [.    1203    1228 ..    1203    1229 .. 0.91
  10 !   15.4   0.0   2.5e-05     0.016       1      26 [.    1237    1263 ..    1237    1263 .. 0.92
  11 !    9.6   0.0    0.0019       1.2       1      26 [.    1271    1297 ..    1271    1297 .. 0.92
  12 ?    3.2   0.0      0.22   1.4e+02       1      26 [.    1305    1331 ..    1305    1331 .. 0.79
  13 ?    5.4   0.0     0.043        27       1      25 [.    1339    1364 ..    1339    1365 .. 0.86
  14 !   15.0   0.0   3.4e-05     0.022       1      25 [.    1373    1398 ..    1373    1399 .. 0.91
  15 !   11.6   0.1   0.00044      0.28       3      25 ..    1409    1432 ..    1407    1433 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00046
                 HHT-SSHHHHHHHHHHHHH CS
        HEAT   8 llsDpspeVReaAakaLga 26 
                  + D++++VR+aA++aLg+
  EEA18488.1 938 FMGDSDSNVRRAAVEALGT 956
                 479**************95 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 7.1e-05
                 HHHHHHHHH.T-SSHHHHHHHHHHHHH CS
        HEAT   1 llPlllkll.sDpspeVReaAakaLga 26 
                 +l ++++ l +D+++ VR+aA+kaLg+
  EEA18488.1 964 ILEAVIRRLeNDEDSGVRRAAIKALGT 990
                 6889999999***************95 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.019
                  HHHHHHHHH.T-SSHHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLga 26  
                  +l ++++ l +  ++ +R aA+kaLg+
  EEA18488.1  998 ILEAVIRQLeNNRDSYIRHAAIKALGT 1024
                  67888888889999***********95 PP

  == domain 4  score: 15.8 bits;  conditional E-value: 1.9e-05
                  HHHHHHHHH.T-SSHHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLga 26  
                  ll ++++ l +D++++VR++A+kaLg+
  EEA18488.1 1032 LLEAVIRRLeNDENSNVRYTAIKALGT 1058
                  6888999999***************95 PP

  == domain 5  score: 13.4 bits;  conditional E-value: 0.00011
                  HHHHHHHHH.T-SSHHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLga 26  
                  +l ++++ l +D+++ VR+aA++aLg+
  EEA18488.1 1066 ILEAVIRRLeNDKDSGVRRAAIEALGT 1092
                  6889999999***************95 PP

  == domain 6  score: 10.9 bits;  conditional E-value: 0.00068
                  T-SSHHHHHHHHHHHHH CS
        HEAT   10 sDpspeVReaAakaLga 26  
                  +D+ ++VR +A++aLg+
  EEA18488.1 1111 NDETWDVRHTAINALGT 1127
                  9**************95 PP

  == domain 7  score: 11.2 bits;  conditional E-value: 0.00055
                  HHHHHHHHH.T-SSHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLg 25  
                  ll ++++ l + ++++VR+aA++aL 
  EEA18488.1 1135 LLEAVIRRLeNNTEWNVRRAAINALS 1160
                  688899999899************96 PP

  == domain 8  score: 11.1 bits;  conditional E-value: 0.00061
                  HHHHHHHHH.T-SSHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaL 24  
                  +l ++++ l +D+++ VR+aA++aL
  EEA18488.1 1169 ILEAVIRRLeNDEDSGVRRAAIEAL 1193
                  6889999999**************9 PP

  == domain 9  score: 14.5 bits;  conditional E-value: 4.9e-05
                  HHHHHHHHH.T-SSHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLg 25  
                  +l ++++ l +D+ + VR+aA++aL 
  EEA18488.1 1203 ILEAVIRRLeNDEKWYVRRAAIEALR 1228
                  6889999999**************96 PP

  == domain 10  score: 15.4 bits;  conditional E-value: 2.5e-05
                  HHHHHHHHH.T-SSHHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLga 26  
                  +l ++++ l +D+++ VR+aA++a+g+
  EEA18488.1 1237 ILEAVIRRLeNDENSYVRYAAIEAIGT 1263
                  6889999999***************95 PP

  == domain 11  score: 9.6 bits;  conditional E-value: 0.0019
                  HHHHHHHHH.T-SSHHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLga 26  
                  +l ++++ l +D+++ V +aA++aLg+
  EEA18488.1 1271 ILEAVIRRLeNDEDSGVKRAAIEALGT 1297
                  6889999999***************95 PP

  == domain 12  score: 3.2 bits;  conditional E-value: 0.22
                  HHHHHHHHH.T-SSHHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLga 26  
                  +l ++++ l +D+   +R+aA+k+Lg+
  EEA18488.1 1305 ILEIVIRQLeNDEGFYIRYAAIKTLGT 1331
                  57777777867777779********95 PP

  == domain 13  score: 5.4 bits;  conditional E-value: 0.043
                  HHHHHHHHH.T-SSHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLg 25  
                  +l ++++ l + ++++ R+aA++aLg
  EEA18488.1 1339 ILKAMIHQLeNNEDSDMRRAAIEALG 1364
                  566778888899*************9 PP

  == domain 14  score: 15.0 bits;  conditional E-value: 3.4e-05
                  HHHHHHHHH.T-SSHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLg 25  
                  ll ++++ l +D+ + VR+aA+kaL 
  EEA18488.1 1373 LLEAVIRRLeNDEKWYVRRAAIKALS 1398
                  6888999999**************96 PP

  == domain 15  score: 11.6 bits;  conditional E-value: 0.00044
                  HH.HHHHHT-SSHHHHHHHHHHHH CS
        HEAT    3 Pl.llkllsDpspeVReaAakaLg 25  
                  ++ +++l +D+++ VR+aA+kaL 
  EEA18488.1 1409 DAvICRLENDEDSGVRRAAIKALS 1432
                  55256666**************96 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   0.0     0.012       7.4      35      53 ..     937     955 ..     929     956 .. 0.84
   2 !   15.6   0.2   2.6e-05     0.017       2      53 ..     945     989 ..     944     990 .. 0.94
   3 !   11.8   0.0   0.00042      0.27       3      53 ..     980    1023 ..     978    1024 .. 0.89
   4 !   10.2   0.0    0.0013      0.82      27      53 ..    1030    1057 ..    1029    1058 .. 0.83
   5 !    8.7   0.0     0.004       2.6      27      53 ..    1064    1091 ..    1060    1092 .. 0.90
   6 ?    5.2   0.0      0.05        32      27      53 ..    1098    1126 ..    1093    1127 .. 0.82
   7 !   11.8   0.1   0.00041      0.26       1      53 [.    1115    1160 ..    1115    1161 .. 0.94
   8 !   16.0   0.5     2e-05     0.012       1      52 [.    1149    1193 ..    1149    1194 .. 0.95
   9 !   14.6   0.1   5.4e-05     0.034       3      53 ..    1185    1228 ..    1184    1229 .. 0.94
  10 !   15.9   0.0   2.2e-05     0.014       1      53 [.    1217    1262 ..    1217    1263 .. 0.84
  11 ?    6.8   0.0     0.015       9.6      27      53 ..    1269    1296 ..    1265    1297 .. 0.92
  12 ?    4.8   0.0     0.064        41       3      53 ..    1287    1330 ..    1286    1331 .. 0.87
  13 ?    5.4   0.0     0.043        27      27      54 ..    1337    1365 ..    1336    1365 .. 0.88
  14 ?    7.4   0.0      0.01       6.4      27      53 ..    1371    1398 ..    1370    1399 .. 0.91
  15 !   14.4   0.1   6.2e-05      0.04       1      53 [.    1387    1432 ..    1387    1433 .. 0.94

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.012
     HEAT_EZ  35 alLnddsdeVRaaAagaLg 53 
                 +++ d++++VR aA+ aLg
  EEA18488.1 937 NFMGDSDSNVRRAAVEALG 955
                 67889999**********9 PP

  == domain 2  score: 15.6 bits;  conditional E-value: 2.6e-05
     HEAT_EZ   2 rvRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53 
                 +vRraA+ aLG        +++p  p il a +++L++d+d  VR aA+ aLg
  EEA18488.1 945 NVRRAAVEALG--------TQSPWSPNILEAVIRRLENDEDsGVRRAAIKALG 989
                 79********9........99***************998888**********9 PP

  == domain 3  score: 11.8 bits;  conditional E-value: 0.00042
     HEAT_EZ    3 vRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53  
                  vRraA+ aLG        +++p  p+il a ++ L++  d  +R aA+ aLg
  EEA18488.1  980 VRRAAIKALG--------TQSPWPPAILEAVIRQLENNRDsYIRHAAIKALG 1023
                  9********9........99999999*********88888466********9 PP

  == domain 4  score: 10.2 bits;  conditional E-value: 0.0013
     HEAT_EZ   27 peilpaLlalL.nddsdeVRaaAagaLg 53  
                  p++l a +++L nd++++VR++A+ aLg
  EEA18488.1 1030 PALLEAVIRRLeNDENSNVRYTAIKALG 1057
                  78999999***555555**********9 PP

  == domain 5  score: 8.7 bits;  conditional E-value: 0.004
     HEAT_EZ   27 peilpaLlalLnddsd.eVRaaAagaLg 53  
                  p+il a +++L++d+d  VR aA+ aLg
  EEA18488.1 1064 PAILEAVIRRLENDKDsGVRRAAIEALG 1091
                  7899*******887777**********9 PP

  == domain 6  score: 5.2 bits;  conditional E-value: 0.05
     HEAT_EZ   27 peilpaLlalL.nddsd.eVRaaAagaLg 53  
                  p+il a +++L ++d+  +VR +A+ aLg
  EEA18488.1 1098 PAILEAVIRRLeKNDETwDVRHTAINALG 1126
                  67888888888666666999999999998 PP

  == domain 7  score: 11.8 bits;  conditional E-value: 0.00041
     HEAT_EZ    1 wrvRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53  
                  w vR+ A++aLG        +++p  p++l a +++L++    +VR aA+ aL+
  EEA18488.1 1115 WDVRHTAINALG--------TQSPWSPALLEAVIRRLENNTEwNVRRAAINALS 1160
                  99*********9........99999999*********99999***********8 PP

  == domain 8  score: 16.0 bits;  conditional E-value: 2e-05
     HEAT_EZ    1 wrvRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaL 52  
                  w+vRraA++aL+        +++p  p+il a +++L++d+d  VR aA+ aL
  EEA18488.1 1149 WNVRRAAINALS--------TQSPWSPAILEAVIRRLENDEDsGVRRAAIEAL 1193
                  9**********7........9****************998888*******998 PP

  == domain 9  score: 14.6 bits;  conditional E-value: 5.4e-05
     HEAT_EZ    3 vRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53  
                  vRraA+ aL        ++ +pl p+il a +++L++d++  VR aA+ aL+
  EEA18488.1 1185 VRRAAIEAL--------DTKSPLSPAILEAVIRRLENDEKwYVRRAAIEALR 1228
                  899999999........7999*****************************96 PP

  == domain 10  score: 15.9 bits;  conditional E-value: 2.2e-05
     HEAT_EZ    1 wrvRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53  
                  w vRraA+ aL        ++++p  p il a +++L++d+   VR+aA+ a+g
  EEA18488.1 1217 WYVRRAAIEAL--------RTQSPCSPNILEAVIRRLENDENsYVRYAAIEAIG 1262
                  99*********........57777788899999999955555499*******98 PP

  == domain 11  score: 6.8 bits;  conditional E-value: 0.015
     HEAT_EZ   27 peilpaLlalLnddsd.eVRaaAagaLg 53  
                  p+il a +++L++d+d  V+ aA+ aLg
  EEA18488.1 1269 PAILEAVIRRLENDEDsGVKRAAIEALG 1296
                  899********998888**********9 PP

  == domain 12  score: 4.8 bits;  conditional E-value: 0.064
     HEAT_EZ    3 vRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53  
                  v+raA+ aLG        + +pl p+il   ++ L++d+   +R+aA+ +Lg
  EEA18488.1 1287 VKRAAIEALG--------TKSPLSPAILEIVIRQLENDEGfYIRYAAIKTLG 1330
                  7899999998........8888889999999999988888999*****9998 PP

  == domain 13  score: 5.4 bits;  conditional E-value: 0.043
     HEAT_EZ   27 peilpaLlalLnddsd.eVRaaAagaLgn 54  
                  p+il+a++  L++ +d + R aA+ aLg+
  EEA18488.1 1337 PAILKAMIHQLENNEDsDMRRAAIEALGK 1365
                  78999999999777777**********96 PP

  == domain 14  score: 7.4 bits;  conditional E-value: 0.01
     HEAT_EZ   27 peilpaLlalLnddsd.eVRaaAagaLg 53  
                  p++l a +++L++d++  VR aA+ aL+
  EEA18488.1 1371 PALLEAVIRRLENDEKwYVRRAAIKALS 1398
                  78999999*****************998 PP

  == domain 15  score: 14.4 bits;  conditional E-value: 6.2e-05
     HEAT_EZ    1 wrvRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53  
                  w vRraA+ aL+        ++++  p+il+a + +L++d+d  VR aA+ aL+
  EEA18488.1 1387 WYVRRAAIKALS--------TQSLWSPDILDAVICRLENDEDsGVRRAAIKALS 1432
                  99*********7........999999***********998888**********8 PP

>> DUF3385  Domain of unknown function (DUF3385)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.0     0.015       9.8       9      37 ..     962     990 ..     959     991 .. 0.95
   2 ?    3.2   0.0      0.11        73       9      37 ..     996    1024 ..     994    1025 .. 0.95
   3 !    7.3   0.0    0.0063       4.1       9      37 ..    1030    1058 ..    1027    1059 .. 0.95
   4 ?    1.5   0.0      0.39   2.5e+02       9      37 ..    1064    1092 ..    1061    1093 .. 0.94
   5 ?    1.4   0.0      0.41   2.6e+02       9      37 ..    1098    1127 ..    1095    1128 .. 0.89
   6 ?    5.3   0.0     0.027        17       9      36 ..    1133    1160 ..    1130    1162 .. 0.93
   7 ?   -1.6   0.0       3.5   2.3e+03       9      35 ..    1167    1193 ..    1164    1195 .. 0.89
   8 ?    0.6   0.0      0.72   4.6e+02       9      35 ..    1201    1227 ..    1198    1229 .. 0.91
   9 ?    0.3   0.0      0.92   5.9e+02       9      37 ..    1235    1263 ..    1233    1264 .. 0.94
  10 ?   -0.7   0.0       1.9   1.2e+03       9      37 ..    1269    1297 ..    1266    1297 .. 0.93
  11 ?    4.7   0.0      0.04        26       9      50 ..    1303    1344 ..    1300    1362 .. 0.78
  12 !    7.4   0.0    0.0057       3.7       9      36 ..    1371    1398 ..    1368    1399 .. 0.94
  13 ?    1.1   0.0      0.51   3.3e+02       9      37 ..    1405    1433 ..    1402    1505 .. 0.81

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.015
     DUF3385   9 pqLLelLlnilkteqsqsirrevikllGi 37 
                 p++Le +++ l+++++  +rr +ik lG+
  EEA18488.1 962 PNILEAVIRRLENDEDSGVRRAAIKALGT 990
                 899************************96 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.11
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllGi 37  
                  p +Le +++ l+++++  ir  +ik lG+
  EEA18488.1  996 PAILEAVIRQLENNRDSYIRHAAIKALGT 1024
                  789************************96 PP

  == domain 3  score: 7.3 bits;  conditional E-value: 0.0063
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllGi 37  
                  p LLe +++ l+++++ ++r  +ik lG+
  EEA18488.1 1030 PALLEAVIRRLENDENSNVRYTAIKALGT 1058
                  89*************************96 PP

  == domain 4  score: 1.5 bits;  conditional E-value: 0.39
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllGi 37  
                  p +Le +++ l+++++  +rr +i  lG+
  EEA18488.1 1064 PAILEAVIRRLENDKDSGVRRAAIEALGT 1092
                  889***********************996 PP

  == domain 5  score: 1.4 bits;  conditional E-value: 0.41
     DUF3385    9 pqLLelLlnilkte.qsqsirrevikllGi 37  
                  p +Le +++ l+++ +++++r  +i  lG+
  EEA18488.1 1098 PAILEAVIRRLEKNdETWDVRHTAINALGT 1127
                  7899999999988868************96 PP

  == domain 6  score: 5.3 bits;  conditional E-value: 0.027
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllG 36  
                  p LLe +++ l++++++++rr +i  l+
  EEA18488.1 1133 PALLEAVIRRLENNTEWNVRRAAINALS 1160
                  89**********************9986 PP

  == domain 7  score: -1.6 bits;  conditional E-value: 3.5
     DUF3385    9 pqLLelLlnilkteqsqsirrevikll 35  
                  p +Le +++ l+++++  +rr +i  l
  EEA18488.1 1167 PAILEAVIRRLENDEDSGVRRAAIEAL 1193
                  8899*****************999765 PP

  == domain 8  score: 0.6 bits;  conditional E-value: 0.72
     DUF3385    9 pqLLelLlnilkteqsqsirrevikll 35  
                  p +Le +++ l++++++ +rr +i  l
  EEA18488.1 1201 PAILEAVIRRLENDEKWYVRRAAIEAL 1227
                  889******************999765 PP

  == domain 9  score: 0.3 bits;  conditional E-value: 0.92
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllGi 37  
                  p++Le +++ l+++++  +r  +i  +G+
  EEA18488.1 1235 PNILEAVIRRLENDENSYVRYAAIEAIGT 1263
                  899*********************99996 PP

  == domain 10  score: -0.7 bits;  conditional E-value: 1.9
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllGi 37  
                  p +Le +++ l+++++  ++r +i  lG+
  EEA18488.1 1269 PAILEAVIRRLENDEDSGVKRAAIEALGT 1297
                  889*********************99995 PP

  == domain 11  score: 4.7 bits;  conditional E-value: 0.04
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllGilGALDPykhkqve 50  
                  p +Le++++ l++++   ir  +ik+lG+     P   k + 
  EEA18488.1 1303 PAILEIVIRQLENDEGFYIRYAAIKTLGTQSSWSPAILKAMI 1344
                  889*************************86666666666555 PP

  == domain 12  score: 7.4 bits;  conditional E-value: 0.0057
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllG 36  
                  p LLe +++ l++++++ +rr +ik l+
  EEA18488.1 1371 PALLEAVIRRLENDEKWYVRRAAIKALS 1398
                  89***********************996 PP

  == domain 13  score: 1.1 bits;  conditional E-value: 0.51
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllGi 37  
                  p++L+ ++  l+++++  +rr +ik l++
  EEA18488.1 1405 PDILDAVICRLENDEDSGVRRAAIKALST 1433
                  8999999999***************9976 PP

>> Cohesin_HEAT  HEAT repeat associated with sister chromatid cohesion
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.0     0.021        14      28      42 .]     940     954 ..     936     954 .. 0.88
   2 !    9.6   0.1    0.0018       1.2      16      42 .]     961     988 ..     961     988 .. 0.90
   3 ?    2.6   0.0      0.28   1.8e+02      16      41 ..    1029    1055 ..    1028    1056 .. 0.86
   4 !    7.7   0.2     0.007       4.5      16      42 .]    1063    1090 ..    1063    1090 .. 0.91
   5 ?   -0.9   0.0       3.4   2.2e+03      16      28 ..    1097    1109 ..    1097    1109 .. 0.89
   6 ?   -2.0   0.0       7.6   4.9e+03      16      28 ..    1132    1144 ..    1132    1144 .. 0.87
   7 !   10.5   0.0   0.00091      0.58      16      42 .]    1166    1193 ..    1165    1193 .. 0.91
   8 ?    5.8   0.0     0.026        17      16      42 .]    1200    1227 ..    1199    1227 .. 0.90
   9 ?    5.6   0.0     0.031        20      16      42 .]    1234    1261 ..    1233    1261 .. 0.90
  10 !    7.6   0.1    0.0073       4.7      16      42 .]    1268    1295 ..    1268    1295 .. 0.91
  11 ?    3.0   0.0      0.21   1.3e+02      16      42 .]    1370    1397 ..    1370    1397 .. 0.87
  12 ?    5.8   0.1     0.028        18      16      42 .]    1404    1431 ..    1401    1431 .. 0.89
  13 ?   -0.6   0.0       2.8   1.8e+03      16      28 ..    1438    1450 ..    1436    1450 .. 0.89

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.021
                   HSS-HHHHHHHHHHH CS
  Cohesin_HEAT  28 tDsspsVRdAaLell 42 
                    Ds++ VR Aa+e l
    EEA18488.1 940 GDSDSNVRRAAVEAL 954
                   5***********986 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.0018
                   SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT  16 apevldtiarrl.tDsspsVRdAaLell 42 
                   +p +l++++rrl +D+++ VR Aa++ l
    EEA18488.1 961 SPNILEAVIRRLeNDEDSGVRRAAIKAL 988
                   699*********56**********9875 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.28
                    SHHHHHHHHHHH.HSS-HHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLel 41  
                    +p +l++++rrl +D+ + VR +a++ 
    EEA18488.1 1029 SPALLEAVIRRLeNDENSNVRYTAIKA 1055
                    58899*******55******9999876 PP

  == domain 4  score: 7.7 bits;  conditional E-value: 0.007
                    SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLell 42  
                    +p +l++++rrl +D ++ VR Aa+e l
    EEA18488.1 1063 SPAILEAVIRRLeNDKDSGVRRAAIEAL 1090
                    589*********56***********976 PP

  == domain 5  score: -0.9 bits;  conditional E-value: 3.4
                    SHHHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrlt 28  
                    +p +l++++rrl+
    EEA18488.1 1097 SPAILEAVIRRLE 1109
                    589********95 PP

  == domain 6  score: -2.0 bits;  conditional E-value: 7.6
                    SHHHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrlt 28  
                    +p +l++++rrl+
    EEA18488.1 1132 SPALLEAVIRRLE 1144
                    5889*******95 PP

  == domain 7  score: 10.5 bits;  conditional E-value: 0.00091
                    SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLell 42  
                    +p +l++++rrl +D+++ VR Aa+e l
    EEA18488.1 1166 SPAILEAVIRRLeNDEDSGVRRAAIEAL 1193
                    689*********56***********976 PP

  == domain 8  score: 5.8 bits;  conditional E-value: 0.026
                    SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLell 42  
                    +p +l++++rrl +D++  VR Aa+e l
    EEA18488.1 1200 SPAILEAVIRRLeNDEKWYVRRAAIEAL 1227
                    799*********55***********976 PP

  == domain 9  score: 5.6 bits;  conditional E-value: 0.031
                    SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLell 42  
                    +p +l++++rrl +D+ + VR Aa+e +
    EEA18488.1 1234 SPNILEAVIRRLeNDENSYVRYAAIEAI 1261
                    799*********55***********976 PP

  == domain 10  score: 7.6 bits;  conditional E-value: 0.0073
                    SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLell 42  
                    +p +l++++rrl +D+++ V+ Aa+e l
    EEA18488.1 1268 SPAILEAVIRRLeNDEDSGVKRAAIEAL 1295
                    589*********56***********976 PP

  == domain 11  score: 3.0 bits;  conditional E-value: 0.21
                    SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLell 42  
                    +p +l++++rrl +D++  VR Aa++ l
    EEA18488.1 1370 SPALLEAVIRRLeNDEKWYVRRAAIKAL 1397
                    58899*******55**********9875 PP

  == domain 12  score: 5.8 bits;  conditional E-value: 0.028
                    SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLell 42  
                    +p++ld+++ rl +D+++ VR Aa++ l
    EEA18488.1 1404 SPDILDAVICRLeNDEDSGVRRAAIKAL 1431
                    69999999999956**********9875 PP

  == domain 13  score: -0.6 bits;  conditional E-value: 2.8
                    SHHHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrlt 28  
                    +p +l++++rrl+
    EEA18488.1 1438 SPAILEAVIRRLE 1450
                    699********95 PP

>> HEAT_PBS  PBS lyase HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.0     0.013       8.6       1      20 [.     946     967 ..     946     974 .. 0.71
   2 !    8.7   0.1    0.0051       3.3       1      21 [.     980    1002 ..     980    1008 .. 0.76
   3 ?    6.5   0.1     0.026        17       1      19 [.    1014    1034 ..    1014    1042 .. 0.69
   4 ?    6.1   0.0     0.034        22       1      26 [.    1048    1075 ..    1048    1076 .. 0.83
   5 ?    7.7   0.2      0.01       6.6       1      25 [.    1082    1108 ..    1082    1110 .. 0.80
   6 ?    1.5   0.0       1.1   6.9e+02       1      13 [.    1117    1129 ..    1117    1145 .. 0.76
   7 ?    3.9   0.1      0.17   1.1e+02       1      25 [.    1151    1177 ..    1151    1179 .. 0.80
   8 ?    2.2   0.1      0.63     4e+02       1      10 [.    1185    1194 ..    1185    1213 .. 0.77
   9 ?    4.1   0.1      0.15        96       1      14 [.    1219    1232 ..    1219    1247 .. 0.71
  10 ?    5.7   0.1     0.048        30       1      26 [.    1253    1280 ..    1253    1281 .. 0.82
  11 ?    1.7   0.0      0.93   5.9e+02       1      11 [.    1287    1297 ..    1287    1312 .. 0.90
  12 ?    3.7   0.0      0.21   1.3e+02       1      16 [.    1321    1338 ..    1321    1349 .. 0.74
  13 ?    4.1   0.1      0.15        98       2      13 ..    1356    1367 ..    1355    1383 .. 0.75
  14 ?    4.5   0.0      0.11        69       1      12 [.    1389    1400 ..    1389    1412 .. 0.78
  15 ?    6.4   0.3     0.028        18       1      26 [.    1423    1450 ..    1423    1451 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.013
                 HHHHHHHHHHHCTS..GGGHHH CS
    HEAT_PBS   1 vRraAakaLgqlgd..eeaipa 20 
                 vRraA++aLg+     + +++a
  EEA18488.1 946 VRRAAVEALGTQSPwsPNILEA 967
                 9*********976656555554 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.0051
                  HHHHHHHHHHHCTS..GGGHHHH CS
    HEAT_PBS    1 vRraAakaLgqlgd..eeaipaL 21  
                  vRraA+kaLg+     +++++a 
  EEA18488.1  980 VRRAAIKALGTQSPwpPAILEAV 1002
                  9*********9887766666655 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.026
                  HHHHHHHHHHHCTS..GGGHH CS
    HEAT_PBS    1 vRraAakaLgqlgd..eeaip 19  
                  +R+aA+kaLg+  +  ++ ++
  EEA18488.1 1014 IRHAAIKALGTQSSwsPALLE 1034
                  6*********99885533333 PP

  == domain 4  score: 6.1 bits;  conditional E-value: 0.034
                  HHHHHHHHHHHCTS..GGGHHHHHHHCT CS
    HEAT_PBS    1 vRraAakaLgqlgd..eeaipaLleaLq 26  
                  vR+ A+kaLg+     +++++a ++ L+
  EEA18488.1 1048 VRYTAIKALGTQSPwsPAILEAVIRRLE 1075
                  9*********998888888887777665 PP

  == domain 5  score: 7.7 bits;  conditional E-value: 0.01
                  HHHHHHHHHHHCTS..GGGHHHHHHHC CS
    HEAT_PBS    1 vRraAakaLgqlgd..eeaipaLleaL 25  
                  vRraA++aLg+     +++++a ++ L
  EEA18488.1 1082 VRRAAIEALGTQSPwsPAILEAVIRRL 1108
                  9*********98887777777766655 PP

  == domain 6  score: 1.5 bits;  conditional E-value: 1.1
                  HHHHHHHHHHHCT CS
    HEAT_PBS    1 vRraAakaLgqlg 13  
                  vR+ A+ aLg+  
  EEA18488.1 1117 VRHTAINALGTQS 1129
                  8*********865 PP

  == domain 7  score: 3.9 bits;  conditional E-value: 0.17
                  HHHHHHHHHHHCTS..GGGHHHHHHHC CS
    HEAT_PBS    1 vRraAakaLgqlgd..eeaipaLleaL 25  
                  vRraA+ aL +     +++++a ++ L
  EEA18488.1 1151 VRRAAINALSTQSPwsPAILEAVIRRL 1177
                  9********998887777777777666 PP

  == domain 8  score: 2.2 bits;  conditional E-value: 0.63
                  HHHHHHHHHH CS
    HEAT_PBS    1 vRraAakaLg 10  
                  vRraA++aL 
  EEA18488.1 1185 VRRAAIEALD 1194
                  9*******96 PP

  == domain 9  score: 4.1 bits;  conditional E-value: 0.15
                  HHHHHHHHHHHCTS CS
    HEAT_PBS    1 vRraAakaLgqlgd 14  
                  vRraA++aL +   
  EEA18488.1 1219 VRRAAIEALRTQSP 1232
                  9********98665 PP

  == domain 10  score: 5.7 bits;  conditional E-value: 0.048
                  HHHHHHHHHHHCTS..GGGHHHHHHHCT CS
    HEAT_PBS    1 vRraAakaLgqlgd..eeaipaLleaLq 26  
                  vR+aA++a+g+     +++++a ++ L+
  EEA18488.1 1253 VRYAAIEAIGTQSPwsPAILEAVIRRLE 1280
                  9*********998888888887777665 PP

  == domain 11  score: 1.7 bits;  conditional E-value: 0.93
                  HHHHHHHHHHH CS
    HEAT_PBS    1 vRraAakaLgq 11  
                  v raA++aLg+
  EEA18488.1 1287 VKRAAIEALGT 1297
                  78*******97 PP

  == domain 12  score: 3.7 bits;  conditional E-value: 0.21
                  HHHHHHHHHHHCTS..GG CS
    HEAT_PBS    1 vRraAakaLgqlgd..ee 16  
                  +R+aA+k Lg+  +  ++
  EEA18488.1 1321 IRYAAIKTLGTQSSwsPA 1338
                  6*********98775444 PP

  == domain 13  score: 4.1 bits;  conditional E-value: 0.15
                  HHHHHHHHHHCT CS
    HEAT_PBS    2 RraAakaLgqlg 13  
                  RraA++aLg+  
  EEA18488.1 1356 RRAAIEALGKQS 1367
                  9********965 PP

  == domain 14  score: 4.5 bits;  conditional E-value: 0.11
                  HHHHHHHHHHHC CS
    HEAT_PBS    1 vRraAakaLgql 12  
                  vRraA+kaL + 
  EEA18488.1 1389 VRRAAIKALSTQ 1400
                  9********875 PP

  == domain 15  score: 6.4 bits;  conditional E-value: 0.028
                  HHHHHHHHHHHCTS..GGGHHHHHHHCT CS
    HEAT_PBS    1 vRraAakaLgqlgd..eeaipaLleaLq 26  
                  vRraA+kaL +     +++++a ++ L+
  EEA18488.1 1423 VRRAAIKALSTQSLwsPAILEAVIRRLE 1450
                  9*********999988888888777665 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.1   0.1   4.5e-16   2.9e-13       1     163 [.     421     578 ..     421     581 .. 0.84

  Alignments for each domain:
  == domain 1  score: 50.1 bits;  conditional E-value: 4.5e-16
                 SCEEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-....-HCHHHCCCCTS--SSS-CCHHHHCCS.CCCEEEEEE-STT-SS-T CS
       NACHT   1 rlvilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgna.rsladllfsqlpepaapvsevwavllel.perlLlilDglDelvtdl 97 
                 r ++++G+aG+GKTtL +k++++  +++l ++ f+ +++++lr+l+  ++    +++ lf++  e    v++ ++  l +  +++L +lDglDe++   
  EEA18488.1 421 RRILIRGRAGVGKTTLCKKIVHDFLHQQLWADLFDRIIWIPLRRLKGMSDLdEFFRQELFKHEAERDCLVTKLRKTALDQtHKKTLWLLDGLDEVSGYR 519
                 679********************************************998877788888888888888888877766655167899**********855 PP

                 CH.........HHHHHCTTTTT--EEEEEEECCCHHHHCTTSSCE..EEEE--TCCHHHHHHHHCT CS
       NACHT  98 gqkekqpvrtlLselirkkllpeasllltvrpralrdleeqleeaivlevegfsesrrkqlvrkyf 163
                 ++     +   L+e+++  ll e  +++t+rp a++ l+ +  +   le  gf  +++++++ k  
  EEA18488.1 520 NP-----SGADLTEIFNS-LLNEDNVIITSRPHAVKLLGLTPFD-LELETVGFHLNQVQAYLAKAV 578
                 55.....77889999998.9999************554444334.488888999999999987765 PP

>> Adaptin_N  Adaptin N terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.5   0.0   1.8e-09   1.1e-06      28     370 ..     915    1369 ..     896    1390 .. 0.67
   2 ?    2.4   0.0     0.073        46     115     177 ..    1373    1432 ..    1366    1456 .. 0.74

  Alignments for each domain:
  == domain 1  score: 27.5 bits;  conditional E-value: 1.8e-09
                  HHHHHHHHCT---GHHHHHHHCCCC.SS-CHHHHHHHHHHHHHCTTSCCHHCCCCHHHHHHCCSSSHHHHHHHHHHHCCC--CCCHHHHHHHHHHHH CS
   Adaptin_N   28 kkliylialGedvsflffevvklva.skdfelKrlvYlylellaeesedlalLvtnslqkDlkdpnqlirglALrvLssirvpelaedlapaikkll 123 
                  kk++  +a+  ++sf +++++ +++  +d  ++r    +l   +  s++++  v+  l +D    ++ +r  A+++L++  +p    +l+  i++l 
  EEA18488.1  915 KKILRALAYRWHMSFNLMDITTNFMgDSDSNVRRAAVEALGTQSPWSPNILEAVIRRLEND---EDSGVRRAAIKALGTQ-SPWPPAILEAVIRQLE 1007
                  5555555555556655555555555555555666555555555555555444444444443...4445555555555542.2222223333333333 PP

                  T-SSHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHCTT-SSHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHH............HCS-HHH CS
   Adaptin_N  124 kdrspyvrkkAalailklykkdpdllrkqlveeikellsdkdpgvvlaAvalleeikkndrlllkllpklvrrLcnll............teldpwl 208 
                  + r++y+r +A+ a+ +  + +p ll+      i  l +d++  v ++A+++l     +      +l+  +rrL+n              ++ +pw 
  EEA18488.1 1008 NNRDSYIRHAAIKALGTQSSWSPALLEA----VIRRLENDENSNVRYTAIKALGTQ-SPWSP--AILEAVIRRLENDKdsgvrraaiealGTQSPWS 1097
                  4555566666665555555555555322....233333556666666666665555.33333..455555555553335555555555555555555 PP

                  HHHHHHHHCC---SSHHHH.............................................................................. CS
   Adaptin_N  209 qvkiiklltrlarqepeer.............................................................................. 227 
                   +++  +++rl ++++  +                                                                              
  EEA18488.1 1098 PAILEAVIRRLEKNDETWDvrhtainalgtqspwspalleavirrlenntewnvrraainalstqspwspaileavirrlendedsgvrraaieald 1194
                  5555555555555555555555555666666666666666666666666666667778888888888888888888888888888889********* PP

                  .........................................HHHHHHHCGGCG.CSSCHHHHHHHHHCCHCCCCSTHHHCCHHCHHHHHH.SSCCTC CS
   Adaptin_N  228 .......................................skkellesllnllq.ssnnaVlletvnlivelapknelivlavnaLvrlls.skdenl 283 
                                                         s  ++le +  +l+   n +V ++++++i + +p +++   + +a +r l+ ++d ++
  EEA18488.1 1195 tksplspaileavirrlendekwyvrraaiealrtqspcS-PNILEAVIRRLEnDENSYVRYAAIEAIGTQSPWSPA---ILEAVIRRLEnDEDSGV 1287
                  ********************99999999998888765542.679999999999667788***********9998885...99****999999***** PP

                  HHHHHCHHHHHHHHXXTTTTTTTCCCCSXXTTSXHHHHHHHHHHHCCCXXTTTHHHHHHHHHHHTTSSXXHHHHHHHHHHHHHHHHH CS
   Adaptin_N  284 ryvaLrtllkivkkepkavqhldlkifllktdddvsirlkaldlllklvdesNvkeivkeLkkyvkevadedfksklvkaIgrlaek 370 
                  + +a+++l + +  + +a+   ++ i+ l++d+  +ir  a+ +l +  ++s   +i+k +  ++++  d d+++++++a+g+ + +
  EEA18488.1 1288 KRAAIEALGTKSPLS-PAIL--EIVIRQLENDEGFYIRYAAIKTLGT--QSSWSPAILKAMIHQLENNEDSDMRRAAIEALGKQSPW 1369
                  ************999.8885..7999*****************9864..4555689*********9999***********9976655 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.073
                  HHHHHHHHHT.-SSHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHCTT-SSHHHHHHHHHHHH CS
   Adaptin_N  115 lapaikkllk.drspyvrkkAalailklykkdpdllrkqlveeikellsdkdpgvvlaAvalle 177 
                  l++a+ + l+ d++ yvr++A+ a+ +    +pd+l       i  l +d+d gv +aA+++l 
  EEA18488.1 1373 LLEAVIRRLEnDEKWYVRRAAIKALSTQSLWSPDILDA----VICRLENDEDSGVRRAAIKALS 1432
                  555555555526666*******9999999999999633....45555599999***99999986 PP

>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.8   0.0   1.2e-10   7.9e-08      24     209 ..      45     299 ..      19     317 .. 0.74

  Alignments for each domain:
  == domain 1  score: 31.8 bits;  conditional E-value: 1.2e-10
                 EEEEE.TTEEEEEEEETTEEEEEEE--...SSHHHHHHHHHHHHHHHC.--SEEEEEEEEEES...STTT-TT-EEEEEE......EEESSSCCGCCTH CS
   PNP_UDP_1  24 pfgregrgfkfvtGtlkgkpvvivstG...iGkpnaavvaeirllkef.gvkaiiriGtaGgl...npdlkvGDvvipdd......ainfdgrsplygp 109
                 p+ +   +  + +G+l g+ +vi++      G++ aa   + r+   f +    +++G+ Gg+   n+d+++GDvv+++       +i++d++ +  g 
  EEA18488.1  45 PNPS-TDSNAYELGELDGHYIVITCLPvgvYGTVAAA-NVVSRMRSTFpRLQYGLMVGIGGGVpgkNNDIRLGDVVVSKPvgqhggVIQYDYGKTVKGG 141
                 3333.48889999999999999999997766888888.4444444455556677999***********************4444444777777777766 PP

                 HCC.......................................TCCCCTTSSEE--HHHHHHHHH.........CHHTTT...................T CS
   PNP_UDP_1 110 kee.......................................gqyfpdsydapadpelrallke.........aaealg...................i 141
                 k e                                       +  +  ++++ + ++l++ l+e                                  +
  EEA18488.1 142 KLEptgalnkppqtllthmsqleakrvtgsednlktimeealIRNPDIEARFSPPEQLTDFLFEssyhhaageD----TcekcdkerlvkrkpretrtP 236
                 666***************************************77777777777777777777776666443332....13444666777777888889* PP

                 TEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTBETTCTC CS
   PNP_UDP_1 142 kvhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArelgipfaairvvsdlaaggadaea 209
                  +h+G++a+++++  ++e ++rl  + g+ + eME+a +       ++p ++ir++ d+ + +  +++
  EEA18488.1 237 YIHYGLIASGNQVMKDSETRDRLALQHGILCFEMEAAGLMD-----ELPTLVIRGICDYCDSHKQKQW 299
                 ***********************************987643.....6788888888886665544444 PP

>> NLRC4_HD2  NLRC4 helical domain HD2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.9   0.1     5e-10   3.2e-07       1      82 [.     740     819 ..     740     848 .. 0.74

  Alignments for each domain:
  == domain 1  score: 30.9 bits;  conditional E-value: 5e-10
   NLRC4_HD2   1 HlsiQeFlAAlyvvlseeeeksevlkeflelekketkellsls.kkaldkalksknghldlflrFLfGLlsesnqrlleellg 82 
                 Hl++QeF+AA y++++ ++e+s+ l   l+    +++++ + s +k l++   + +g++d+f rF+ GLl    ++++  +l+
  EEA18488.1 740 HLTFQEFFAAQYFIRCWRSESSKLL-IYLKAGFARETSIAKISpEKFLREE--KYSGRYDVFWRFVTGLLYNIDKQQVCLFLE 819
                 ***********************66.4444444443244443434444444..56899************9888877777766 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.2   0.0   3.7e-10   2.4e-07      22     111 ..     422     511 ..     410     553 .. 0.72

  Alignments for each domain:
  == domain 1  score: 30.2 bits;  conditional E-value: 3.7e-10
                 EEEEEESTTSSHHHHHHHHCCSH..CCCCC.CBTEEEEEEEESXXHHHHHHHXXHHHHHCCCTTSSSS-STTSHHHHHHHHCCCTTEEEEEEE CS
      NB-ARC  22 vvalvGmgGvGKttlakqilnks..deveg.rFdsvawvvvsktdkseeiletilkeLslseddleekeeveslkrklvrlLltkrfllvlDD 111
                  + + G++GvGKttl k+i++++  +++    Fd+++w+ + +    +++ e+  +eL ++e++++   ++  +k+ l +   +k++l +lD 
  EEA18488.1 422 RILIRGRAGVGKTTLCKKIVHDFlhQQLWAdLFDRIIWIPLRRLKGMSDLDEFFRQELFKHEAERDCLVTKL-RKTALDQT--HKKTLWLLDG 511
                 57899****************96335554459**************************99988887777666.66666664..5578888764 PP

>> CO_deh_flav_C  CO dehydrogenase flavoprotein C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0      0.07        45      37      74 ..     938     975 ..     920     986 .. 0.86
   2 ?    0.7   0.0      0.89   5.7e+02      45      74 ..    1014    1043 ..    1008    1047 .. 0.86
   3 ?    1.3   0.0      0.58   3.7e+02      45      74 ..    1048    1077 ..    1044    1081 .. 0.89
   4 ?    1.3   0.0       0.6   3.8e+02      45      73 ..    1082    1110 ..    1078    1116 .. 0.89
   5 ?    2.1   0.0      0.34   2.2e+02      45      76 ..    1117    1148 ..    1111    1157 .. 0.87
   6 ?    0.5   0.0         1   6.6e+02      46      74 ..    1152    1180 ..    1146    1191 .. 0.85
   7 ?   -2.6   0.0       9.5   6.1e+03      45      74 ..    1219    1248 ..    1214    1251 .. 0.86
   8 ?    2.8   0.0       0.2   1.3e+02      44      74 ..    1252    1282 ..    1247    1293 .. 0.89
   9 ?    3.0   0.0      0.18   1.2e+02      45      74 ..    1355    1384 ..    1322    1395 .. 0.91
  10 ?   -1.6   0.0       4.7     3e+03      45      74 ..    1423    1452 ..    1401    1457 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.07
                    EESSSSS-EE-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C  37 fggvaptpvraekaeaaLiGkplseelleeaakaleee 74 
                    f+g ++  vr  ++ea+ + +p+s ++le+++++le++
     EEA18488.1 938 FMGDSDSNVRRAAVEALGTQSPWSPNILEAVIRRLEND 975
                    666677789999***********************987 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.89
                     EE-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C   45 vraekaeaaLiGkplseelleeaakaleee 74  
                     +r  +++a+ + +++s +lle+++++le++
     EEA18488.1 1014 IRHAAIKALGTQSSWSPALLEAVIRRLEND 1043
                     6778888889999**************987 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.58
                     EE-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C   45 vraekaeaaLiGkplseelleeaakaleee 74  
                     vr ++++a+ + +p+s ++le+++++le++
     EEA18488.1 1048 VRYTAIKALGTQSPWSPAILEAVIRRLEND 1077
                     78899999999***************9987 PP

  == domain 4  score: 1.3 bits;  conditional E-value: 0.6
                     EE-HHHHHHHTTSBSSHHHHHHHHHHHHT CS
  CO_deh_flav_C   45 vraekaeaaLiGkplseelleeaakalee 73  
                     vr  ++ea+ + +p+s ++le+++++le+
     EEA18488.1 1082 VRRAAIEALGTQSPWSPAILEAVIRRLEK 1110
                     6778899999***************9987 PP

  == domain 5  score: 2.1 bits;  conditional E-value: 0.34
                     EE-HHHHHHHTTSBSSHHHHHHHHHHHHTTCH CS
  CO_deh_flav_C   45 vraekaeaaLiGkplseelleeaakaleeels 76  
                     vr +++ a+ + +p+s +lle+++++le++ +
     EEA18488.1 1117 VRHTAINALGTQSPWSPALLEAVIRRLENNTE 1148
                     677888999999***************98765 PP

  == domain 6  score: 0.5 bits;  conditional E-value: 1
                     E-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C   46 raekaeaaLiGkplseelleeaakaleee 74  
                     r  ++ a+ + +p+s ++le+++++le++
     EEA18488.1 1152 RRAAINALSTQSPWSPAILEAVIRRLEND 1180
                     666778888999**************987 PP

  == domain 7  score: -2.6 bits;  conditional E-value: 9.5
                     EE-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C   45 vraekaeaaLiGkplseelleeaakaleee 74  
                     vr  ++ea+ + +p s ++le+++++le++
     EEA18488.1 1219 VRRAAIEALRTQSPCSPNILEAVIRRLEND 1248
                     67788899999999999********99987 PP

  == domain 8  score: 2.8 bits;  conditional E-value: 0.2
                     -EE-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C   44 pvraekaeaaLiGkplseelleeaakaleee 74  
                      vr  ++ea  + +p+s ++le+++++le++
     EEA18488.1 1252 YVRYAAIEAIGTQSPWSPAILEAVIRRLEND 1282
                     6889999*********************987 PP

  == domain 9  score: 3.0 bits;  conditional E-value: 0.18
                     EE-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C   45 vraekaeaaLiGkplseelleeaakaleee 74  
                     +r  ++ea+ + +p+s +lle+++++le++
     EEA18488.1 1355 MRRAAIEALGKQSPWSPALLEAVIRRLEND 1384
                     67788999999****************987 PP

  == domain 10  score: -1.6 bits;  conditional E-value: 4.7
                     EE-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C   45 vraekaeaaLiGkplseelleeaakaleee 74  
                     vr  +++a+ + + +s ++le+++++le+e
     EEA18488.1 1423 VRRAAIKALSTQSLWSPAILEAVIRRLENE 1452
                     56667778888899999*******999986 PP

>> Vac14_Fab1_bd  Vacuolar 14 Fab1-binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.0      0.52   3.3e+02      29      51 ..     932     954 ..     924     988 .. 0.71
   2 ?    4.0   0.0      0.12        75      25      51 ..    1029    1056 ..    1014    1086 .. 0.80
   3 ?    0.4   0.0       1.6     1e+03      27      51 ..    1065    1090 ..    1056    1095 .. 0.80
   4 ?    1.0   0.0      0.99   6.3e+02      24      51 ..    1165    1193 ..    1151    1197 .. 0.74
   5 ?    6.6   0.0     0.019        12      19      51 ..    1228    1261 ..    1218    1292 .. 0.83
   6 ?   -1.8   0.0       7.8     5e+03      23      51 ..    1300    1329 ..    1285    1359 .. 0.77
   7 ?   -0.1   0.0       2.2   1.4e+03      71      88 ..    1410    1427 ..    1388    1432 .. 0.75

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.52
  Vac14_Fab1_bd  29 vkpvlkcfsDkdsrvRyyacEsl 51 
                    +++  + + D+ds vR  a+E+l
     EEA18488.1 932 MDITTNFMGDSDSNVRRAAVEAL 954
                    44444555666666666666655 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.12
  Vac14_Fab1_bd   25 leeivkpvlkcf.sDkdsrvRyyacEsl 51  
                        +++ v++ + +D++s vRy+a+ +l
     EEA18488.1 1029 SPALLEAVIRRLeNDENSNVRYTAIKAL 1056
                     556778888766369999******9987 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 1.6
  Vac14_Fab1_bd   27 eivkpvlkcf.sDkdsrvRyyacEsl 51  
                      i++ v++ + +Dkds vR  a+E+l
     EEA18488.1 1065 AILEAVIRRLeNDKDSGVRRAAIEAL 1090
                     67888887663699999999999987 PP

  == domain 4  score: 1.0 bits;  conditional E-value: 0.99
  Vac14_Fab1_bd   24 yleeivkpvlkcf.sDkdsrvRyyacEsl 51  
                         i++ v++ + +D+ds vR  a+E+l
     EEA18488.1 1165 WSPAILEAVIRRLeNDEDSGVRRAAIEAL 1193
                     55678888887663689999999999987 PP

  == domain 5  score: 6.6 bits;  conditional E-value: 0.019
  Vac14_Fab1_bd   19 kkikeyleeivkpvlkcf.sDkdsrvRyyacEsl 51  
                     ++ +++  +i++ v++ + +D++s vRy a+E++
     EEA18488.1 1228 RTQSPCSPNILEAVIRRLeNDENSYVRYAAIEAI 1261
                     456788999****999873699999*******86 PP

  == domain 6  score: -1.8 bits;  conditional E-value: 7.8
  Vac14_Fab1_bd   23 eyleeivkpvlkcfs.DkdsrvRyyacEsl 51  
                     +    i+++v++ ++ D+   +Ry a+ +l
     EEA18488.1 1300 PLSPAILEIVIRQLEnDEGFYIRYAAIKTL 1329
                     555678899998875266778999998766 PP

  == domain 7  score: -0.1 bits;  conditional E-value: 2.2
  Vac14_Fab1_bd   71 dalvklvaDsdesvksga 88  
                      ++++l  D+d+ v+++a
     EEA18488.1 1410 AVICRLENDEDSGVRRAA 1427
                     467999999999999886 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0       8.7   5.6e+03      54      83 ..     282     316 ..     276     338 .. 0.72
   2 !   15.1   0.0   3.5e-05     0.022      20      63 ..     416     454 ..     404     541 .. 0.66
   3 ?    2.1   1.0      0.36   2.3e+02      75      75 ..    1134    1134 ..     893    1227 .. 0.70
   4 ?    1.0   0.4      0.77     5e+02     123     123 ..    1305    1305 ..    1202    1468 .. 0.63

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 8.7
      AAA_16  54 iflrgkcdqlesa.....ipysalaqalareellr 83 
                 +++rg cd ++s       py+a++ a+ ++ ll 
  EEA18488.1 282 LVIRGICDYCDSHkqkqwQPYAAFTAAAYAKLLLS 316
                 56778888884444557899999888776655555 PP

  == domain 2  score: 15.1 bits;  conditional E-value: 3.5e-05
      AAA_16  20 rsgrpelvllsGesGvGKsslvrellralekdggiflrgkcdql 63 
                 r  rp+ +l++G +GvGK++l +++ + +  +     + ++d +
  EEA18488.1 416 RNARPRRILIRGRAGVGKTTLCKKIVHDFLHQ-----QLWADLF 454
                 5567899***************9998876666.....3333333 PP

  == domain 3  score: 2.1 bits;  conditional E-value: 0.36
      AAA_16   75 a 75  
                  a
  EEA18488.1 1134 A 1134
                  2 PP

  == domain 4  score: 1.0 bits;  conditional E-value: 0.77
      AAA_16  123 l 123 
                  +
  EEA18488.1 1305 I 1305
                  2 PP

>> EPL1  Enhancer of polycomb-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0       4.5   2.9e+03     140     156 ..     958     974 ..     940     975 .. 0.84
   2 ?    1.3   0.0      0.62     4e+02     140     156 ..    1094    1110 ..    1012    1111 .. 0.71
   3 ?   -0.6   0.0       2.4   1.5e+03     139     156 ..    1162    1179 ..    1126    1180 .. 0.69
   4 ?    7.0   0.0     0.011       6.9     121     156 ..    1212    1247 ..    1211    1248 .. 0.91
   5 ?    1.0   0.0      0.75   4.8e+02     140     156 ..    1299    1315 ..    1261    1316 .. 0.73
   6 ?    0.4   0.0       1.2   7.7e+02     121     156 ..    1382    1417 ..    1381    1452 .. 0.50

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 4.5
        EPL1 140 ekisediFEivmdrlEk 156
                 ++ s++i E v+ rlE+
  EEA18488.1 958 SPWSPNILEAVIRRLEN 974
                 7889************7 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.62
        EPL1  140 ekisediFEivmdrlEk 156 
                  ++ s++i E v+ rlEk
  EEA18488.1 1094 SPWSPAILEAVIRRLEK 1110
                  56677777777777777 PP

  == domain 3  score: -0.6 bits;  conditional E-value: 2.4
        EPL1  139 vekisediFEivmdrlEk 156 
                   ++ s++i E v+ rlE+
  EEA18488.1 1162 QSPWSPAILEAVIRRLEN 1179
                  277888999999999986 PP

  == domain 4  score: 7.0 bits;  conditional E-value: 0.011
        EPL1  121 EeDekWLeelnekrkkegvekisediFEivmdrlEk 156 
                  E DekW+ +  +     + +++s++i E v+ rlE+
  EEA18488.1 1212 ENDEKWYVRRAAIEALRTQSPCSPNILEAVIRRLEN 1247
                  89*****999998778888****************7 PP

  == domain 5  score: 1.0 bits;  conditional E-value: 0.75
        EPL1  140 ekisediFEivmdrlEk 156 
                  +++s++i Eiv+ +lE+
  EEA18488.1 1299 SPLSPAILEIVIRQLEN 1315
                  78899999999999996 PP

  == domain 6  score: 0.4 bits;  conditional E-value: 1.2
        EPL1  121 EeDekWLeelnekrkkegvekisediFEivmdrlEk 156 
                  E DekW+ +  + +  ++ +  s+di   v+ rlE+
  EEA18488.1 1382 ENDEKWYVRRAAIKALSTQSLWSPDILDAVICRLEN 1417
                  567777766666644444444455555555555543 PP

>> DNA_alkylation  DNA alkylation repair enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.66   4.2e+02      50      90 ..    1031    1070 ..    1011    1080 .. 0.69
   2 !   14.4   1.7   3.7e-05     0.024      36     210 ..    1084    1258 ..    1075    1261 .. 0.84
   3 !    7.8   0.2    0.0037       2.4      44     143 ..    1331    1430 ..    1285    1439 .. 0.83

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.66
  DNA_alkylation   50 eelqelaeeLwksperEerllAldlltqakkklaeadlely 90  
                      + l++++++L ++++   r++A++ l  + ++   a+le +
      EEA18488.1 1031 ALLEAVIRRLENDENSNVRYTAIKALGTQSPWSP-AILEAV 1070
                      456788999999999***********88777744.444443 PP

  == domain 2  score: 14.4 bits;  conditional E-value: 3.7e-05
  DNA_alkylation   36 rklakeffkelkle.eelqelaeeLwkspe.rEerllAldlltqakkklaeadlelyeklvetinnWdlvDslaskivgalladkperrdllk 126 
                      r+ +  + ++ + + ++l++++++L k++e  + r++A+  l  + ++ ++a+le + + +e   +W++  ++++++ ++  ++    +++++
      EEA18488.1 1084 RAAIEALGTQSPWSpAILEAVIRRLEKNDEtWDVRHTAINALGTQSPW-SPALLEAVIRRLENNTEWNVRRAAINALSTQSPWSPAILEAVIR 1175
                      44444444444444577888999999999889**********888877.5588**************************999998888999** PP

  DNA_alkylation  127 eWaksenlWerRaAivatlklikktdlellleiaeelladkedfiqkAiGwaLrelsktdpdlveeFlekhakrmprlslreAi 210 
                      ++ ++e+  +rRaAi a l  +     + l +++ +l +d+++ ++ A   aLr  s   p+ +e+ + + ++   + ++  Ai
      EEA18488.1 1176 RLENDEDSGVRRAAIEA-LDTKSPLSPAILEAVIRRLENDEKWYVRRAAIEALRTQSPCSPNILEAVIRRLENDENSYVRYAAI 1258
                      ***************98.688899*********************************999999998888866655555555555 PP

  == domain 3  score: 7.8 bits;  conditional E-value: 0.0037
  DNA_alkylation   44 kelkle.eelqelaeeLwksperEerllAldlltqakkklaeadlelyeklvetinnWdlvDslaskivgalladkperrdllkeWaksenlW 135 
                      ++ + + ++l++ + +L +++  ++r +A++ l ++ ++ ++a+le + + +e  ++W +  ++++++ ++ l++ +  ++++ ++ ++e+  
      EEA18488.1 1331 TQSSWSpAILKAMIHQLENNEDSDMRRAAIEALGKQSPW-SPALLEAVIRRLENDEKWYVRRAAIKALSTQSLWSPDILDAVICRLENDEDSG 1422
                      444444567888999999999999999999999887777.55779999999999999988888889999999999777888889999999999 PP

  DNA_alkylation  136 erRaAiva 143 
                      +rRaAi a
      EEA18488.1 1423 VRRAAIKA 1430
                      99999976 PP

>> Arm  Armadillo/beta-catenin-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0       2.1   1.3e+03      20      37 ..     938     955 ..     932     955 .. 0.87
   2 ?    2.2   0.0      0.31     2e+02      10      37 ..     961     989 ..     960     989 .. 0.90
   3 ?   -1.9   0.0       6.4   4.1e+03      14      36 ..     999    1022 ..     998    1023 .. 0.73
   4 ?   -0.1   0.0       1.7   1.1e+03      14      37 ..    1067    1091 ..    1066    1091 .. 0.83
   5 ?   -1.5   0.0       4.5   2.9e+03      14      36 ..    1170    1193 ..    1169    1193 .. 0.81
   6 ?    0.0   0.0       1.6     1e+03      14      37 ..    1272    1296 ..    1271    1296 .. 0.84
   7 ?    2.1   0.0      0.34   2.2e+02      14      37 ..    1340    1364 ..    1338    1365 .. 0.90
   8 ?    1.9   0.0      0.38   2.5e+02       6      37 ..    1400    1432 ..    1398    1433 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 2.1
                 HTTTSSHHHHHHHHHHHH CS
         Arm  20 LLssedeevqeeAawALs 37 
                 ++ + d +v+++A+ AL+
  EEA18488.1 938 FMGDSDSNVRRAAVEALG 955
                 566899**********96 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.31
                 HTTHHHHHHHHTT.TSSHHHHHHHHHHHH CS
         Arm  10 eaGavppLvrLLs.sedeevqeeAawALs 37 
                 + +++++ +r L+ +ed +v+++A  AL+
  EEA18488.1 961 SPNILEAVIRRLEnDEDSGVRRAAIKALG 989
                 5799999*****************99986 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 6.4
                  HHHHHHHTT.TSSHHHHHHHHHHH CS
         Arm   14 vppLvrLLs.sedeevqeeAawAL 36  
                  +++ +r L+ + d  ++++A  AL
  EEA18488.1  999 LEAVIRQLEnNRDSYIRHAAIKAL 1022
                  788899999777777777777666 PP

  == domain 4  score: -0.1 bits;  conditional E-value: 1.7
                  HHHHHHHTT.TSSHHHHHHHHHHHH CS
         Arm   14 vppLvrLLs.sedeevqeeAawALs 37  
                  +++ +r L+ ++d +v+++A  AL+
  EEA18488.1 1067 LEAVIRRLEnDKDSGVRRAAIEALG 1091
                  56677778889*********99996 PP

  == domain 5  score: -1.5 bits;  conditional E-value: 4.5
                  HHHHHHHTT.TSSHHHHHHHHHHH CS
         Arm   14 vppLvrLLs.sedeevqeeAawAL 36  
                  +++ +r L+ +ed +v+++A  AL
  EEA18488.1 1170 LEAVIRRLEnDEDSGVRRAAIEAL 1193
                  566777788899*******98887 PP

  == domain 6  score: 0.0 bits;  conditional E-value: 1.6
                  HHHHHHHTT.TSSHHHHHHHHHHHH CS
         Arm   14 vppLvrLLs.sedeevqeeAawALs 37  
                  +++ +r L+ +ed +v+++A  AL+
  EEA18488.1 1272 LEAVIRRLEnDEDSGVKRAAIEALG 1296
                  56677778889*********99996 PP

  == domain 7  score: 2.1 bits;  conditional E-value: 0.34
                  HHHHHHHTT.TSSHHHHHHHHHHHH CS
         Arm   14 vppLvrLLs.sedeevqeeAawALs 37  
                  +++ ++ L+ +ed +++++A  AL+
  EEA18488.1 1340 LKAMIHQLEnNEDSDMRRAAIEALG 1364
                  7788999**************9997 PP

  == domain 8  score: 1.9 bits;  conditional E-value: 0.38
                  HHHHHTTHHHHHHHHTT.TSSHHHHHHHHHHHH CS
         Arm    6 davieaGavppLvrLLs.sedeevqeeAawALs 37  
                  + +++  ++++ +  L+ +ed +v+++A  ALs
  EEA18488.1 1400 QSLWSPDILDAVICRLEnDEDSGVRRAAIKALS 1432
                  567888899999999999**********99997 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   4.1e-06    0.0027       8     123 ..     423     539 ..     417     554 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 4.1e-06
      AAA_22   8 lvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelkaerlsseell.ealeqalrarav.ielliiDEaqhlr 104
                 +++ G +G+GKTtl++++++ +  ++  ++  ++++ + l  +++ +dl + + ++l   ++a    ++++l ++l++ + ++   + l ++D  + ++
  EEA18488.1 423 ILIRGRAGVGKTTLCKKIVHDFLHQQLWADLFDRIIWIPLRRLKGMSDLDEFFRQELFK-HEA----ERDCLvTKLRKTALDQTHkKTLWLLDGLDEVS 516
                 7899******************9888888899999999999999999999999999993.333....5566658888777777767899********96 PP

      AAA_22 105 ..s...eealeeL.rsllnlsrkgv 123
                   +    + l+e+  slln  +++v
  EEA18488.1 517 gyRnpsGADLTEIfNSLLN--EDNV 539
                 6614554444444477777..5554 PP

>> Nore1-SARAH  Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       4.1   2.6e+03       5      22 ..    1031    1048 ..    1029    1051 .. 0.83
   2 ?   -1.4   0.0       3.7   2.3e+03       5      21 ..    1168    1184 ..    1166    1187 .. 0.82
   3 ?    1.0   0.0      0.62     4e+02       4      23 ..    1201    1220 ..    1200    1221 .. 0.88
   4 ?   -1.2   0.0       3.1     2e+03       6      23 ..    1237    1254 ..    1234    1254 .. 0.89
   5 ?   -1.5   0.0       3.9   2.5e+03       5      20 ..    1270    1285 ..    1268    1289 .. 0.82
   6 ?    0.9   0.0      0.67   4.3e+02       5      24 ..    1372    1391 ..    1370    1392 .. 0.88
   7 ?    5.4   0.0     0.027        17       4      22 ..    1439    1457 ..    1437    1461 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 4.1
  Nore1-SARAH    5 PELqnFLriLeeEEeeei 22  
                   ++L+  +r Le  E+  +
   EEA18488.1 1031 ALLEAVIRRLENDENSNV 1048
                   789********9998766 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 3.7
  Nore1-SARAH    5 PELqnFLriLeeEEeee 21  
                   ++L+  +r Le  E+  
   EEA18488.1 1168 AILEAVIRRLENDEDSG 1184
                   78*********999865 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 0.62
  Nore1-SARAH    4 lPELqnFLriLeeEEeeeiq 23  
                    ++L+  +r Le  E+ +++
   EEA18488.1 1201 PAILEAVIRRLENDEKWYVR 1220
                   579*************9997 PP

  == domain 4  score: -1.2 bits;  conditional E-value: 3.1
  Nore1-SARAH    6 ELqnFLriLeeEEeeeiq 23  
                   +L+  +r Le  E+ +++
   EEA18488.1 1237 ILEAVIRRLENDENSYVR 1254
                   69999********99985 PP

  == domain 5  score: -1.5 bits;  conditional E-value: 3.9
  Nore1-SARAH    5 PELqnFLriLeeEEee 20  
                   ++L+  +r Le  E+ 
   EEA18488.1 1270 AILEAVIRRLENDEDS 1285
                   78*********99986 PP

  == domain 6  score: 0.9 bits;  conditional E-value: 0.67
  Nore1-SARAH    5 PELqnFLriLeeEEeeeiqq 24  
                   ++L+  +r Le  E+ ++++
   EEA18488.1 1372 ALLEAVIRRLENDEKWYVRR 1391
                   78*************99975 PP

  == domain 7  score: 5.4 bits;  conditional E-value: 0.027
  Nore1-SARAH    4 lPELqnFLriLeeEEeeei 22  
                    ++L+  +r Le EE+ e+
   EEA18488.1 1439 PAILEAVIRRLENEEDSEV 1457
                   579*************998 PP

>> Cnd3  Nuclear condensing complex subunits, C-term domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0      0.06        39      25      87 ..     997    1056 ..     985    1059 .. 0.74
   2 ?   -0.2   0.0      0.73   4.7e+02      39      56 ..    1079    1096 ..    1052    1193 .. 0.59
   3 ?    2.4   0.0      0.11        73     115     146 ..    1334    1365 ..    1232    1366 .. 0.85
   4 ?   -2.1   0.0       2.7   1.7e+03      30      59 ..    1377    1406 ..    1371    1412 .. 0.71
   5 ?    0.6   0.0      0.42   2.7e+02      26      64 ..    1407    1445 ..    1392    1464 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.06
                  HHHHHTHHHHHC-SSHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHS-HHHHHHHHHHH CS
        Cnd3   25 slleslilpavrskeaairelglkcLglfclldkklakenlklflqalskgneelkiialkai 87  
                  ++le  i++  ++++  ir +++k+Lg+ +  +  l +  ++ + +    +n++++ +a+ka+
  EEA18488.1  997 AILEAVIRQLENNRDSYIRHAAIKALGTQSSWSPALLEAVIRRLEND---ENSNVRYTAIKAL 1056
                  57777777777788*************99988888777666555432...2456777777765 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.73
                  SHHHHHHHHHHHHHHHTT CS
        Cnd3   39 eaairelglkcLglfcll 56  
                  +  +r++++++Lg+ +  
  EEA18488.1 1079 DSGVRRAAIEALGTQSPW 1096
                  556666666666655433 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.11
                  ....HHHHHHHHHHC-TT-HHHHHHHHHHHHH CS
        Cnd3  115 essksllkllykaLdsednpelqaiaaeglcK 146 
                  + s  +lk ++++L+++++++++ +a+e+l K
  EEA18488.1 1334 SWSPAILKAMIHQLENNEDSDMRRAAIEALGK 1365
                  45667899999999988889999999998865 PP

  == domain 4  score: -2.1 bits;  conditional E-value: 2.7
                  THHHHHC-SSHHHHHHHHHHHHHHHTT-HH CS
        Cnd3   30 lilpavrskeaairelglkcLglfclldkk 59  
                   i++  + ++  +r++++k+L++ +l + +
  EEA18488.1 1377 VIRRLENDEKWYVRRAAIKALSTQSLWSPD 1406
                  4444444447889********999998766 PP

  == domain 5  score: 0.6 bits;  conditional E-value: 0.42
                  HHHHTHHHHHC-SSHHHHHHHHHHHHHHHTT-HHHHHHH CS
        Cnd3   26 lleslilpavrskeaairelglkcLglfclldkklaken 64  
                  +l+  i++  + ++  +r++++k+L++ +l +  + +  
  EEA18488.1 1407 ILDAVICRLENDEDSGVRRAAIKALSTQSLWSPAILEAV 1445
                  7788888888888999************99988776655 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   0.00012     0.075       1      92 [.     423     536 ..     423     554 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 0.00012
                 EEEESSTTSSHHHHHHHHHHHH..........T....HEEEEEETTTCSSS........STTHHHHHHHHHHHHHHHTS.....TSEEEEEETGGGHHH CS
         AAA   1 vllyGppGtGKTllakavakel..........g....vefleisgsellsk........yvgesekkirelfkeakeka.....kpsilfiDEidalak 72 
                 +l+ G  G+GKT+l+k +++++          +    +++ +++g++ l++        +  e+   + +l k+    a     k++  ++D +d++ +
  EEA18488.1 423 ILIRGRAGVGKTTLCKKIVHDFlhqqlwadlfDriiwIPLRRLKGMSDLDEffrqelfkHEAERDCLVTKLRKT----AldqthKKTLWLLDGLDEVSG 517
                 57889****************54433333333133446677777777776666665433334444445555555....334446679999999999999 PP

                 HHTTCCCHHHHHHHHHHHHH CS
         AAA  73 srsgseseeeervvnqLlte 92 
                  r + +  + +++ n Ll+e
  EEA18488.1 518 YR-NPSGADLTEIFNSLLNE 536
                 99.67788888888988876 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   0.00013     0.081       1      22 [.     422     443 ..     422     450 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 0.00013
                 EEEEE--TTSSHHHHHHHHHHH CS
    NTPase_1   1 kvfiTGppGvGKtTlvkkvlel 22 
                 +++i G+ GvGKtTl+kk+++ 
  EEA18488.1 422 RILIRGRAGVGKTTLCKKIVHD 443
                 5899**************9875 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   0.00036      0.23       1      33 [.     423     451 ..     423     524 .. 0.51

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00036
      AAA_18   1 IlltGtpGvGKttlakeLskrlgfgvnlrdvak 33 
                 Il+ G +GvGKttl+k +       + ++++++
  EEA18488.1 423 ILIRGRAGVGKTTLCKKIVHD----FLHQQLWA 451
                 8999*************9554....22222222 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   0.00045      0.29       1      25 [.     423     447 ..     423     473 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00045
  RNA_helicase   1 iwlyGpsgeGKStlakeLakallkk 25 
                   i++ G++g+GK+tl+k++++++l +
    EEA18488.1 423 ILIRGRAGVGKTTLCKKIVHDFLHQ 447
                   6899****************99954 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00068      0.43       5      59 ..     423     478 ..     419     543 .. 0.55

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00068
      AAA_14   5 lvitGaRrvGKTtllkqlikell......vkkesilyinldderd....kkladpekllelilek 59 
                 ++i+G   vGKTtl+k+++++ l         ++i+ i l + +     +         e+++++
  EEA18488.1 423 ILIRGRAGVGKTTLCKKIVHDFLhqqlwaDLFDRIIWIPLRRLKGmsdlD---------EFFRQE 478
                 7899***************9999555554334555555555433322220.........222222 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00065      0.42      23      93 ..     423     500 ..     411     521 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00065
    ATPase_2  23 yfiYGpegsGKtaLlkeiienledkdk.....yviyyialre.esiskldefie.....eeeekkklekal.giavpkaelee 93 
                 ++i G+ g+GKt+L k+i+   ++++      ++i  i+lr+ +  s ldef++           ++e+    ++++k++l++
  EEA18488.1 423 ILIRGRAGVGKTTLCKKIVHDFLHQQLwadlfDRIIWIPLRRlKGMSDLDEFFRqelfkH-----EAERDClVTKLRKTALDQ 500
                 6899****************9988776777887777777776255788999988544332.....333322144444444444 PP

>> AAA_17  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   0.1    0.0046       2.9       2      19 ..     427     444 ..     426     521 .. 0.84
   2 ?   -2.3   0.0       8.6   5.5e+03      46      87 ..    1174    1215 ..    1170    1265 .. 0.61
   3 ?   -0.8   0.0         3   1.9e+03      44      87 ..    1342    1385 ..    1332    1431 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.0046
                 E-TTSSHHHHHHHHHHHH CS
      AAA_17   2 GgPGsGKgtqceklveky 19 
                 G  G+GK+t+c+k+v+++
  EEA18488.1 427 GRAGVGKTTLCKKIVHDF 444
                 567************986 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 8.6
                  HCTSHHHHHHHHHHHHHHHHHHHHHSSEEEEEE-SEEEETTE CS
      AAA_17   46 mrklpleekkelqkeaaekiaeeakkkgvlvdghprikeqag 87  
                  +r+l+++e+  +++ a+e++  ++  + ++++   r  e+++
  EEA18488.1 1174 IRRLENDEDSGVRRAAIEALDTKSPLSPAILEAVIRRLENDE 1215
                  556666777777777777777666555566655555444443 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 3
                  HHHCTSHHHHHHHHHHHHHHHHHHHHHSSEEEEEE-SEEEETTE CS
      AAA_17   44 demrklpleekkelqkeaaekiaeeakkkgvlvdghprikeqag 87  
                    +++l+++e+ ++++ a+e++ +++  + +l++   r  e+++
  EEA18488.1 1342 AMIHQLENNEDSDMRRAAIEALGKQSPWSPALLEAVIRRLENDE 1385
                  45668999999999999999999998777788777777666655 PP

>> PduV-EutP  Ethanolamine utilisation - propanediol utilisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   0.00067      0.43       2      26 ..     421     445 ..     420     449 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00067
   PduV-EutP   2 kkilliGkvgsGKttLtqalkgeel 26 
                 ++il+ G+ g+GKttL++++ ++ l
  EEA18488.1 421 RRILIRGRAGVGKTTLCKKIVHDFL 445
                 68999*************9977655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1558 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       567  (0.0316247); expected 358.6 (0.02)
Passed bias filter:                      516  (0.0287802); expected 358.6 (0.02)
Passed Vit filter:                        93  (0.00518713); expected 17.9 (0.001)
Passed Fwd filter:                        30  (0.00167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              28  [number of targets reported over threshold]
# CPU time: 1.21u 0.37s 00:00:01.58 Elapsed: 00:00:00.58
# Mc/sec: 8078.10
//
Query:       EEA18489.1  [L=1549]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.7e-82  270.0  33.2    9.8e-17   61.1   1.0    6.8  6  HEAT_2          HEAT repeats
    2.9e-55  179.5  12.6      0.012   15.8   0.0   15.8 15  HEAT            HEAT repeat
      3e-33  113.8  19.5      0.012   16.1   0.5   14.5 15  HEAT_EZ         HEAT-like repeat
    7.1e-17   61.8   0.0        3.6    7.5   0.0   12.4 13  DUF3385         Domain of unknown function (DUF3385)
    1.7e-16   60.2  25.2       0.58   10.5   0.0   12.8 13  Cohesin_HEAT    HEAT repeat associated with sister chromatid 
    6.7e-15   54.2  44.1        3.3    8.7   0.1   15.4 15  HEAT_PBS        PBS lyase HEAT-like repeat
    1.5e-13   51.0   0.1    2.8e-13   50.1   0.1    1.5  1  NACHT           NACHT domain
    2.7e-10   39.4   0.0    1.1e-06   27.5   0.0    3.8  2  Adaptin_N       Adaptin N terminal region
    4.5e-08   32.6   0.0    7.8e-08   31.9   0.0    1.3  1  PNP_UDP_1       Phosphorylase superfamily
    9.1e-08   32.7   0.1    3.2e-07   31.0   0.1    2.0  1  NLRC4_HD2       NLRC4 helical domain HD2
    9.2e-08   31.6   0.0    2.4e-07   30.2   0.0    1.6  1  NB-ARC          NB-ARC domain
    1.1e-06   28.8   2.7         44    4.3   0.0    9.0 10  CO_deh_flav_C   CO dehydrogenase flavoprotein C-terminal doma
    6.5e-06   26.7   1.3         12    6.6   0.0    7.9  6  Vac14_Fab1_bd   Vacuolar 14 Fab1-binding region
    0.00013   22.4   5.6      0.022   15.1   0.0    5.6  3  AAA_16          AAA ATPase domain
    0.00018   21.9   0.0        6.9    7.0   0.0    7.1  6  EPL1            Enhancer of polycomb-like
    0.00024   20.9   9.7      0.024   14.4   1.7    3.8  3  DNA_alkylation  DNA alkylation repair enzyme
    0.00033   20.6   0.0      2e+02    2.2   0.0    7.5  8  Arm             Armadillo/beta-catenin-like repeat
    0.00061   20.1   0.0     0.0026   18.0   0.0    2.1  1  AAA_22          AAA domain
     0.0012   18.7   0.0         17    5.4   0.0    6.5  7  Nore1-SARAH     Novel Ras effector 1 C-terminal SARAH (Sav/Ra
     0.0032   16.7   0.2         38    3.3   0.0    6.1  5  Cnd3            Nuclear condensing complex subunits, C-term d
  ------ inclusion threshold ------
       0.02   15.3   0.0      0.075   13.5   0.0    2.0  1  AAA             ATPase family associated with various cellula
      0.043   13.7   0.0      0.081   12.8   0.0    1.4  1  NTPase_1        NTPase
      0.053   14.1   0.0       0.23   12.0   0.0    2.2  1  AAA_18          AAA domain
       0.12   12.7   0.0       0.29   11.5   0.0    1.6  1  RNA_helicase    RNA helicase
       0.17   11.9   0.0       0.43   10.6   0.0    1.7  1  AAA_14          AAA domain
       0.19   11.6   0.0       0.42   10.5   0.0    1.5  1  ATPase_2        ATPase domain predominantly from Archaea
       0.19   12.1   0.7        2.9    8.3   0.1    3.3  3  AAA_17          AAA domain
       0.22   11.2   0.0       0.43   10.3   0.0    1.4  1  PduV-EutP       Ethanolamine utilisation - propanediol utilis
        4.1    6.1   4.3         57    2.3   0.1    4.0  4  API5            Apoptosis inhibitory protein 5 (API5)


Domain annotation for each model (and alignments):
>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.6   0.1   4.1e-13   2.5e-10      11      88 .]     899     980 ..     887     980 .. 0.82
   2 !   59.0   1.0   7.1e-19   4.4e-16       1      88 []     990    1082 ..     990    1082 .. 0.91
   3 !   52.6   2.6   7.3e-17   4.5e-14       2      87 ..    1093    1184 ..    1092    1185 .. 0.88
   4 !   61.1   1.0   1.6e-19   9.8e-17       1      88 []    1195    1287 ..    1195    1287 .. 0.92
   5 !   52.7   0.1   6.9e-17   4.3e-14       4      87 ..    1300    1388 ..    1297    1389 .. 0.90
   6 !   44.7   2.4   2.1e-14   1.3e-11       1      87 [.    1365    1455 ..    1365    1456 .. 0.89

  Alignments for each domain:
  == domain 1  score: 40.6 bits;  conditional E-value: 4.1e-13
      HEAT_2  11 dpdpevrraairaLg.rignp.ealpaLvellededpavRraaaeaLgaig..dpealpaLkellddddddvvReaAaeaLa 88 
                   +   r++++raL+ r++    ++++ ++++ d+d++vRraa+eaLg     +p  l+a  ++l +d+d+ vR+aA++aL+
  EEA18489.1 899 QRESSCRKKILRALAyRWHMSfNLMDITTNFMGDSDSNVRRAAVEALGTQSpwSPNILEAVIRRLENDEDSGVRRAAIKALG 980
                 556668999******755544589************************776457*************************996 PP

  == domain 2  score: 59.0 bits;  conditional E-value: 7.1e-19
      HEAT_2    1 ldaLlqalendpdpevrraairaLgrig..npealpaLvell.ededpavRraaaeaLgaig..dpealpaLkellddddddvvReaAaeaLa 88  
                  l+a + +len  d ++r+aai+aLg++   +p +l+a+++ l +de+++vR++a++aLg     +p+ l+a  ++l +d+d+ vR+aA+eaL+
  EEA18489.1  990 LEAVIRQLENNRDSYIRHAAIKALGTQSswSPALLEAVIRRLeNDENSNVRYTAIKALGTQSpwSPAILEAVIRRLENDKDSGVRRAAIEALG 1082
                  578999*******************665126899********789**************777467**************************96 PP

  == domain 3  score: 52.6 bits;  conditional E-value: 7.3e-17
      HEAT_2    2 daLlqalen.dpdpevrraairaLgrig..npealpaLvell.ededpavRraaaeaLgaig..dpealpaLkellddddddvvReaAaeaL 87  
                  +a + +le+ d+ ++vr++ai aLg++   +p +l+a+++ l ++++++vRraa++aL+     +p+ l+a  ++l +d+d+ vR+aA+eaL
  EEA18489.1 1093 EAVIRRLEKnDETWDVRHTAINALGTQSpwSPALLEAVIRRLeNNTEWNVRRAAINALSTQSpwSPAILEAVIRRLENDEDSGVRRAAIEAL 1184
                  6788888555***************776236899********56799***********9776467**************************9 PP

  == domain 4  score: 61.1 bits;  conditional E-value: 1.6e-19
      HEAT_2    1 ldaLlqalendpdpevrraairaLg..rignpealpaLvell.ededpavRraaaeaLgaig..dpealpaLkellddddddvvReaAaeaLa 88  
                  l+a + +lend+ ++vrraai+aL   +  +p +l+a+++ l +de+++vR+aa+ea+g     +p+ l+a  ++l +d+d+ v++aA+eaL+
  EEA18489.1 1195 LEAVIRRLENDEKWYVRRAAIEALRtqSPCSPNILEAVIRRLeNDENSYVRYAAIEAIGTQSpwSPAILEAVIRRLENDEDSGVKRAAIEALG 1287
                  578999*******************5333789**********889**************777467**************************96 PP

  == domain 5  score: 52.7 bits;  conditional E-value: 6.9e-17
      HEAT_2    4 LlqalendpdpevrraairaLgrig..npealpaLvell.ededpavRraaaeaLgaig..dpealpaLkellddddddvvReaAaeaL 87  
                   + +lend+  ++r+aai++Lg++   +p +l+a++  l ++ed++ Rraa+eaLg+    +p+ l+a  ++l +d++++vR+aA++aL
  EEA18489.1 1300 VIRQLENDEGFYIRYAAIKTLGTQSswSPAILKAMIHQLeNNEDSDMRRAAIEALGKQSpwSPALLEAVIRRLENDEKWYVRRAAIKAL 1388
                  6899******************655126899******99667**************998566**************************9 PP

  == domain 6  score: 44.7 bits;  conditional E-value: 2.1e-14
      HEAT_2    1 ldaLlqalendpdpevrraairaLg..rignpealpaLvell.ededpavRraaaeaLgaig..dpealpaLkellddddddvvReaAaeaL 87  
                  l+a + +lend+ ++vrraai+aL   ++ +p++l+a++  l +ded+ vRraa++aL+     +p+ l+a  ++l +++d++v  + +eaL
  EEA18489.1 1365 LEAVIRRLENDEKWYVRRAAIKALStqSLWSPDILDAVICRLeNDEDSGVRRAAIKALSTQSlwSPAILEAVIRRLENEEDSEVASK-IEAL 1455
                  578999*******************755679***********789*************9666347******************9887.6665 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.5   0.0   0.00048      0.29       8      26 ..     929     947 ..     922     947 .. 0.84
   2 !   14.0   0.0   7.3e-05     0.045       1      26 [.     955     981 ..     955     981 .. 0.92
   3 ?    6.5   0.0      0.02        12       1      26 [.     989    1015 ..     989    1015 .. 0.87
   4 !   15.8   0.0     2e-05     0.012       1      26 [.    1023    1049 ..    1023    1049 .. 0.92
   5 !   13.4   0.0   0.00012     0.071       1      26 [.    1057    1083 ..    1057    1083 .. 0.92
   6 !   11.0   0.0    0.0007      0.43      10      26 ..    1102    1118 ..    1091    1118 .. 0.82
   7 !   11.3   0.1   0.00057      0.35       1      25 [.    1126    1151 ..    1126    1152 .. 0.90
   8 !   11.1   0.0   0.00063      0.39       1      24 [.    1160    1184 ..    1160    1186 .. 0.91
   9 !   14.5   0.0   5.1e-05     0.031       1      25 [.    1194    1219 ..    1194    1220 .. 0.91
  10 !   15.4   0.0   2.6e-05     0.016       1      26 [.    1228    1254 ..    1228    1254 .. 0.92
  11 !    9.6   0.0    0.0019       1.2       1      26 [.    1262    1288 ..    1262    1288 .. 0.92
  12 ?    3.2   0.0      0.22   1.4e+02       1      26 [.    1296    1322 ..    1296    1322 .. 0.79
  13 ?    5.4   0.0     0.044        27       1      25 [.    1330    1355 ..    1330    1356 .. 0.86
  14 !   15.0   0.0   3.5e-05     0.022       1      25 [.    1364    1389 ..    1364    1390 .. 0.91
  15 !   11.6   0.1   0.00045      0.28       3      25 ..    1400    1423 ..    1398    1424 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00048
                 HHT-SSHHHHHHHHHHHHH CS
        HEAT   8 llsDpspeVReaAakaLga 26 
                  + D++++VR+aA++aLg+
  EEA18489.1 929 FMGDSDSNVRRAAVEALGT 947
                 479**************95 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 7.3e-05
                 HHHHHHHHH.T-SSHHHHHHHHHHHHH CS
        HEAT   1 llPlllkll.sDpspeVReaAakaLga 26 
                 +l ++++ l +D+++ VR+aA+kaLg+
  EEA18489.1 955 ILEAVIRRLeNDEDSGVRRAAIKALGT 981
                 6889999999***************95 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.02
                  HHHHHHHHH.T-SSHHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLga 26  
                  +l ++++ l +  ++ +R aA+kaLg+
  EEA18489.1  989 ILEAVIRQLeNNRDSYIRHAAIKALGT 1015
                  67888888889999***********95 PP

  == domain 4  score: 15.8 bits;  conditional E-value: 2e-05
                  HHHHHHHHH.T-SSHHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLga 26  
                  ll ++++ l +D++++VR++A+kaLg+
  EEA18489.1 1023 LLEAVIRRLeNDENSNVRYTAIKALGT 1049
                  6888999999***************95 PP

  == domain 5  score: 13.4 bits;  conditional E-value: 0.00012
                  HHHHHHHHH.T-SSHHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLga 26  
                  +l ++++ l +D+++ VR+aA++aLg+
  EEA18489.1 1057 ILEAVIRRLeNDKDSGVRRAAIEALGT 1083
                  6889999999***************95 PP

  == domain 6  score: 11.0 bits;  conditional E-value: 0.0007
                  T-SSHHHHHHHHHHHHH CS
        HEAT   10 sDpspeVReaAakaLga 26  
                  +D+ ++VR +A++aLg+
  EEA18489.1 1102 NDETWDVRHTAINALGT 1118
                  9**************95 PP

  == domain 7  score: 11.3 bits;  conditional E-value: 0.00057
                  HHHHHHHHH.T-SSHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLg 25  
                  ll ++++ l + ++++VR+aA++aL 
  EEA18489.1 1126 LLEAVIRRLeNNTEWNVRRAAINALS 1151
                  688899999899************96 PP

  == domain 8  score: 11.1 bits;  conditional E-value: 0.00063
                  HHHHHHHHH.T-SSHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaL 24  
                  +l ++++ l +D+++ VR+aA++aL
  EEA18489.1 1160 ILEAVIRRLeNDEDSGVRRAAIEAL 1184
                  6889999999**************9 PP

  == domain 9  score: 14.5 bits;  conditional E-value: 5.1e-05
                  HHHHHHHHH.T-SSHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLg 25  
                  +l ++++ l +D+ + VR+aA++aL 
  EEA18489.1 1194 ILEAVIRRLeNDEKWYVRRAAIEALR 1219
                  6889999999**************96 PP

  == domain 10  score: 15.4 bits;  conditional E-value: 2.6e-05
                  HHHHHHHHH.T-SSHHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLga 26  
                  +l ++++ l +D+++ VR+aA++a+g+
  EEA18489.1 1228 ILEAVIRRLeNDENSYVRYAAIEAIGT 1254
                  6889999999***************95 PP

  == domain 11  score: 9.6 bits;  conditional E-value: 0.0019
                  HHHHHHHHH.T-SSHHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLga 26  
                  +l ++++ l +D+++ V +aA++aLg+
  EEA18489.1 1262 ILEAVIRRLeNDEDSGVKRAAIEALGT 1288
                  6889999999***************95 PP

  == domain 12  score: 3.2 bits;  conditional E-value: 0.22
                  HHHHHHHHH.T-SSHHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLga 26  
                  +l ++++ l +D+   +R+aA+k+Lg+
  EEA18489.1 1296 ILEIVIRQLeNDEGFYIRYAAIKTLGT 1322
                  57777777867777779********95 PP

  == domain 13  score: 5.4 bits;  conditional E-value: 0.044
                  HHHHHHHHH.T-SSHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLg 25  
                  +l ++++ l + ++++ R+aA++aLg
  EEA18489.1 1330 ILKAMIHQLeNNEDSDMRRAAIEALG 1355
                  566778888899*************9 PP

  == domain 14  score: 15.0 bits;  conditional E-value: 3.5e-05
                  HHHHHHHHH.T-SSHHHHHHHHHHHH CS
        HEAT    1 llPlllkll.sDpspeVReaAakaLg 25  
                  ll ++++ l +D+ + VR+aA+kaL 
  EEA18489.1 1364 LLEAVIRRLeNDEKWYVRRAAIKALS 1389
                  6888999999**************96 PP

  == domain 15  score: 11.6 bits;  conditional E-value: 0.00045
                  HH.HHHHHT-SSHHHHHHHHHHHH CS
        HEAT    3 Pl.llkllsDpspeVReaAakaLg 25  
                  ++ +++l +D+++ VR+aA+kaL 
  EEA18489.1 1400 DAvICRLENDEDSGVRRAAIKALS 1423
                  55256666**************96 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   0.0     0.012       7.4      35      53 ..     928     946 ..     920     947 .. 0.84
   2 !   15.7   0.2   2.7e-05     0.017       2      53 ..     936     980 ..     935     981 .. 0.94
   3 !   11.8   0.0   0.00043      0.27       3      53 ..     971    1014 ..     969    1015 .. 0.89
   4 !   10.3   0.0    0.0013      0.82      27      53 ..    1021    1048 ..    1020    1049 .. 0.83
   5 !    8.7   0.0    0.0042       2.6      27      53 ..    1055    1082 ..    1051    1083 .. 0.90
   6 ?    5.2   0.0     0.052        32      27      53 ..    1089    1117 ..    1084    1118 .. 0.82
   7 !   11.8   0.1   0.00042      0.26       1      53 [.    1106    1151 ..    1106    1152 .. 0.94
   8 !   16.1   0.5     2e-05     0.012       1      52 [.    1140    1184 ..    1140    1185 .. 0.95
   9 !   14.6   0.1   5.5e-05     0.034       3      53 ..    1176    1219 ..    1175    1220 .. 0.94
  10 !   15.9   0.0   2.3e-05     0.014       1      53 [.    1208    1253 ..    1208    1254 .. 0.84
  11 ?    6.8   0.0     0.015       9.5      27      53 ..    1260    1287 ..    1256    1288 .. 0.92
  12 ?    4.8   0.0     0.066        41       3      53 ..    1278    1321 ..    1277    1322 .. 0.87
  13 ?    5.4   0.0     0.044        27      27      54 ..    1328    1356 ..    1327    1356 .. 0.88
  14 ?    7.4   0.0      0.01       6.4      27      53 ..    1362    1389 ..    1361    1390 .. 0.91
  15 !   14.4   0.1   6.4e-05      0.04       1      53 [.    1378    1423 ..    1378    1424 .. 0.94

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.012
     HEAT_EZ  35 alLnddsdeVRaaAagaLg 53 
                 +++ d++++VR aA+ aLg
  EEA18489.1 928 NFMGDSDSNVRRAAVEALG 946
                 67889999**********9 PP

  == domain 2  score: 15.7 bits;  conditional E-value: 2.7e-05
     HEAT_EZ   2 rvRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53 
                 +vRraA+ aLG        +++p  p il a +++L++d+d  VR aA+ aLg
  EEA18489.1 936 NVRRAAVEALG--------TQSPWSPNILEAVIRRLENDEDsGVRRAAIKALG 980
                 79********9........99***************998888**********9 PP

  == domain 3  score: 11.8 bits;  conditional E-value: 0.00043
     HEAT_EZ    3 vRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53  
                  vRraA+ aLG        +++p  p+il a ++ L++  d  +R aA+ aLg
  EEA18489.1  971 VRRAAIKALG--------TQSPWPPAILEAVIRQLENNRDsYIRHAAIKALG 1014
                  9********9........99999999*********88888466********9 PP

  == domain 4  score: 10.3 bits;  conditional E-value: 0.0013
     HEAT_EZ   27 peilpaLlalL.nddsdeVRaaAagaLg 53  
                  p++l a +++L nd++++VR++A+ aLg
  EEA18489.1 1021 PALLEAVIRRLeNDENSNVRYTAIKALG 1048
                  78999999***555555**********9 PP

  == domain 5  score: 8.7 bits;  conditional E-value: 0.0042
     HEAT_EZ   27 peilpaLlalLnddsd.eVRaaAagaLg 53  
                  p+il a +++L++d+d  VR aA+ aLg
  EEA18489.1 1055 PAILEAVIRRLENDKDsGVRRAAIEALG 1082
                  7899*******887777**********9 PP

  == domain 6  score: 5.2 bits;  conditional E-value: 0.052
     HEAT_EZ   27 peilpaLlalL.nddsd.eVRaaAagaLg 53  
                  p+il a +++L ++d+  +VR +A+ aLg
  EEA18489.1 1089 PAILEAVIRRLeKNDETwDVRHTAINALG 1117
                  67888888888666666999999999998 PP

  == domain 7  score: 11.8 bits;  conditional E-value: 0.00042
     HEAT_EZ    1 wrvRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53  
                  w vR+ A++aLG        +++p  p++l a +++L++    +VR aA+ aL+
  EEA18489.1 1106 WDVRHTAINALG--------TQSPWSPALLEAVIRRLENNTEwNVRRAAINALS 1151
                  99*********9........99999999*********99999***********8 PP

  == domain 8  score: 16.1 bits;  conditional E-value: 2e-05
     HEAT_EZ    1 wrvRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaL 52  
                  w+vRraA++aL+        +++p  p+il a +++L++d+d  VR aA+ aL
  EEA18489.1 1140 WNVRRAAINALS--------TQSPWSPAILEAVIRRLENDEDsGVRRAAIEAL 1184
                  9**********7........9****************998888*******998 PP

  == domain 9  score: 14.6 bits;  conditional E-value: 5.5e-05
     HEAT_EZ    3 vRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53  
                  vRraA+ aL        ++ +pl p+il a +++L++d++  VR aA+ aL+
  EEA18489.1 1176 VRRAAIEAL--------DTKSPLSPAILEAVIRRLENDEKwYVRRAAIEALR 1219
                  899999999........7999*****************************96 PP

  == domain 10  score: 15.9 bits;  conditional E-value: 2.3e-05
     HEAT_EZ    1 wrvRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53  
                  w vRraA+ aL        ++++p  p il a +++L++d+   VR+aA+ a+g
  EEA18489.1 1208 WYVRRAAIEAL--------RTQSPCSPNILEAVIRRLENDENsYVRYAAIEAIG 1253
                  99*********........57777788899999999955555499*******98 PP

  == domain 11  score: 6.8 bits;  conditional E-value: 0.015
     HEAT_EZ   27 peilpaLlalLnddsd.eVRaaAagaLg 53  
                  p+il a +++L++d+d  V+ aA+ aLg
  EEA18489.1 1260 PAILEAVIRRLENDEDsGVKRAAIEALG 1287
                  899********998888**********9 PP

  == domain 12  score: 4.8 bits;  conditional E-value: 0.066
     HEAT_EZ    3 vRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53  
                  v+raA+ aLG        + +pl p+il   ++ L++d+   +R+aA+ +Lg
  EEA18489.1 1278 VKRAAIEALG--------TKSPLSPAILEIVIRQLENDEGfYIRYAAIKTLG 1321
                  7899999998........8888889999999999988888999*****9998 PP

  == domain 13  score: 5.4 bits;  conditional E-value: 0.044
     HEAT_EZ   27 peilpaLlalLnddsd.eVRaaAagaLgn 54  
                  p+il+a++  L++ +d + R aA+ aLg+
  EEA18489.1 1328 PAILKAMIHQLENNEDsDMRRAAIEALGK 1356
                  78999999999777777**********96 PP

  == domain 14  score: 7.4 bits;  conditional E-value: 0.01
     HEAT_EZ   27 peilpaLlalLnddsd.eVRaaAagaLg 53  
                  p++l a +++L++d++  VR aA+ aL+
  EEA18489.1 1362 PALLEAVIRRLENDEKwYVRRAAIKALS 1389
                  78999999*****************998 PP

  == domain 15  score: 14.4 bits;  conditional E-value: 6.4e-05
     HEAT_EZ    1 wrvRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53  
                  w vRraA+ aL+        ++++  p+il+a + +L++d+d  VR aA+ aL+
  EEA18489.1 1378 WYVRRAAIKALS--------TQSLWSPDILDAVICRLENDEDsGVRRAAIKALS 1423
                  99*********7........999999***********998888**********8 PP

>> DUF3385  Domain of unknown function (DUF3385)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.0     0.016       9.8       9      37 ..     953     981 ..     950     982 .. 0.95
   2 ?    3.2   0.0      0.12        72       9      37 ..     987    1015 ..     985    1016 .. 0.95
   3 !    7.3   0.0    0.0065         4       9      37 ..    1021    1049 ..    1018    1050 .. 0.95
   4 ?    1.5   0.0       0.4   2.5e+02       9      37 ..    1055    1083 ..    1052    1084 .. 0.94
   5 ?    1.4   0.0      0.42   2.6e+02       9      37 ..    1089    1118 ..    1086    1119 .. 0.89
   6 ?    5.3   0.0     0.028        17       9      36 ..    1124    1151 ..    1121    1153 .. 0.93
   7 ?   -1.6   0.0       3.6   2.2e+03       9      35 ..    1158    1184 ..    1155    1186 .. 0.89
   8 ?    0.6   0.0      0.74   4.6e+02       9      35 ..    1192    1218 ..    1189    1220 .. 0.91
   9 ?    0.3   0.0      0.95   5.9e+02       9      37 ..    1226    1254 ..    1224    1255 .. 0.94
  10 ?   -0.7   0.0       1.9   1.2e+03       9      37 ..    1260    1288 ..    1257    1288 .. 0.93
  11 ?    4.7   0.0     0.041        26       9      50 ..    1294    1335 ..    1291    1353 .. 0.78
  12 !    7.5   0.0    0.0059       3.6       9      36 ..    1362    1389 ..    1359    1390 .. 0.94
  13 ?    1.1   0.0      0.52   3.2e+02       9      37 ..    1396    1424 ..    1393    1496 .. 0.81

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.016
     DUF3385   9 pqLLelLlnilkteqsqsirrevikllGi 37 
                 p++Le +++ l+++++  +rr +ik lG+
  EEA18489.1 953 PNILEAVIRRLENDEDSGVRRAAIKALGT 981
                 899************************96 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.12
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllGi 37  
                  p +Le +++ l+++++  ir  +ik lG+
  EEA18489.1  987 PAILEAVIRQLENNRDSYIRHAAIKALGT 1015
                  789************************96 PP

  == domain 3  score: 7.3 bits;  conditional E-value: 0.0065
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllGi 37  
                  p LLe +++ l+++++ ++r  +ik lG+
  EEA18489.1 1021 PALLEAVIRRLENDENSNVRYTAIKALGT 1049
                  89*************************96 PP

  == domain 4  score: 1.5 bits;  conditional E-value: 0.4
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllGi 37  
                  p +Le +++ l+++++  +rr +i  lG+
  EEA18489.1 1055 PAILEAVIRRLENDKDSGVRRAAIEALGT 1083
                  889***********************996 PP

  == domain 5  score: 1.4 bits;  conditional E-value: 0.42
     DUF3385    9 pqLLelLlnilkte.qsqsirrevikllGi 37  
                  p +Le +++ l+++ +++++r  +i  lG+
  EEA18489.1 1089 PAILEAVIRRLEKNdETWDVRHTAINALGT 1118
                  7899999999988868************96 PP

  == domain 6  score: 5.3 bits;  conditional E-value: 0.028
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllG 36  
                  p LLe +++ l++++++++rr +i  l+
  EEA18489.1 1124 PALLEAVIRRLENNTEWNVRRAAINALS 1151
                  89**********************9986 PP

  == domain 7  score: -1.6 bits;  conditional E-value: 3.6
     DUF3385    9 pqLLelLlnilkteqsqsirrevikll 35  
                  p +Le +++ l+++++  +rr +i  l
  EEA18489.1 1158 PAILEAVIRRLENDEDSGVRRAAIEAL 1184
                  8899*****************999765 PP

  == domain 8  score: 0.6 bits;  conditional E-value: 0.74
     DUF3385    9 pqLLelLlnilkteqsqsirrevikll 35  
                  p +Le +++ l++++++ +rr +i  l
  EEA18489.1 1192 PAILEAVIRRLENDEKWYVRRAAIEAL 1218
                  889******************999765 PP

  == domain 9  score: 0.3 bits;  conditional E-value: 0.95
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllGi 37  
                  p++Le +++ l+++++  +r  +i  +G+
  EEA18489.1 1226 PNILEAVIRRLENDENSYVRYAAIEAIGT 1254
                  899*********************99996 PP

  == domain 10  score: -0.7 bits;  conditional E-value: 1.9
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllGi 37  
                  p +Le +++ l+++++  ++r +i  lG+
  EEA18489.1 1260 PAILEAVIRRLENDEDSGVKRAAIEALGT 1288
                  889*********************99995 PP

  == domain 11  score: 4.7 bits;  conditional E-value: 0.041
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllGilGALDPykhkqve 50  
                  p +Le++++ l++++   ir  +ik+lG+     P   k + 
  EEA18489.1 1294 PAILEIVIRQLENDEGFYIRYAAIKTLGTQSSWSPAILKAMI 1335
                  889*************************86666666666555 PP

  == domain 12  score: 7.5 bits;  conditional E-value: 0.0059
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllG 36  
                  p LLe +++ l++++++ +rr +ik l+
  EEA18489.1 1362 PALLEAVIRRLENDEKWYVRRAAIKALS 1389
                  89***********************996 PP

  == domain 13  score: 1.1 bits;  conditional E-value: 0.52
     DUF3385    9 pqLLelLlnilkteqsqsirrevikllGi 37  
                  p++L+ ++  l+++++  +rr +ik l++
  EEA18489.1 1396 PDILDAVICRLENDEDSGVRRAAIKALST 1424
                  8999999999***************9976 PP

>> Cohesin_HEAT  HEAT repeat associated with sister chromatid cohesion
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.0     0.022        14      28      42 .]     931     945 ..     927     945 .. 0.88
   2 !    9.6   0.1    0.0019       1.1      16      42 .]     952     979 ..     952     979 .. 0.90
   3 ?    2.6   0.0      0.29   1.8e+02      16      41 ..    1020    1046 ..    1019    1047 .. 0.86
   4 !    7.7   0.2    0.0072       4.4      16      42 .]    1054    1081 ..    1054    1081 .. 0.91
   5 ?   -0.9   0.0       3.5   2.2e+03      16      28 ..    1088    1100 ..    1088    1100 .. 0.89
   6 ?   -2.0   0.0       7.8   4.8e+03      16      28 ..    1123    1135 ..    1123    1135 .. 0.87
   7 !   10.5   0.0   0.00093      0.58      16      42 .]    1157    1184 ..    1156    1184 .. 0.91
   8 ?    5.8   0.0     0.027        17      16      42 .]    1191    1218 ..    1190    1218 .. 0.90
   9 ?    5.6   0.0     0.032        20      16      42 .]    1225    1252 ..    1224    1252 .. 0.90
  10 !    7.6   0.1    0.0075       4.6      16      42 .]    1259    1286 ..    1259    1286 .. 0.91
  11 ?    3.0   0.0      0.21   1.3e+02      16      42 .]    1361    1388 ..    1361    1388 .. 0.87
  12 ?    5.8   0.1     0.028        18      16      42 .]    1395    1422 ..    1392    1422 .. 0.89
  13 ?   -0.6   0.0       2.8   1.8e+03      16      28 ..    1429    1441 ..    1427    1441 .. 0.89

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.022
                   HSS-HHHHHHHHHHH CS
  Cohesin_HEAT  28 tDsspsVRdAaLell 42 
                    Ds++ VR Aa+e l
    EEA18489.1 931 GDSDSNVRRAAVEAL 945
                   5***********986 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.0019
                   SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT  16 apevldtiarrl.tDsspsVRdAaLell 42 
                   +p +l++++rrl +D+++ VR Aa++ l
    EEA18489.1 952 SPNILEAVIRRLeNDEDSGVRRAAIKAL 979
                   699*********56**********9875 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.29
                    SHHHHHHHHHHH.HSS-HHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLel 41  
                    +p +l++++rrl +D+ + VR +a++ 
    EEA18489.1 1020 SPALLEAVIRRLeNDENSNVRYTAIKA 1046
                    58899*******55******9999876 PP

  == domain 4  score: 7.7 bits;  conditional E-value: 0.0072
                    SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLell 42  
                    +p +l++++rrl +D ++ VR Aa+e l
    EEA18489.1 1054 SPAILEAVIRRLeNDKDSGVRRAAIEAL 1081
                    589*********56***********976 PP

  == domain 5  score: -0.9 bits;  conditional E-value: 3.5
                    SHHHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrlt 28  
                    +p +l++++rrl+
    EEA18489.1 1088 SPAILEAVIRRLE 1100
                    589********95 PP

  == domain 6  score: -2.0 bits;  conditional E-value: 7.8
                    SHHHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrlt 28  
                    +p +l++++rrl+
    EEA18489.1 1123 SPALLEAVIRRLE 1135
                    5889*******95 PP

  == domain 7  score: 10.5 bits;  conditional E-value: 0.00093
                    SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLell 42  
                    +p +l++++rrl +D+++ VR Aa+e l
    EEA18489.1 1157 SPAILEAVIRRLeNDEDSGVRRAAIEAL 1184
                    689*********56***********976 PP

  == domain 8  score: 5.8 bits;  conditional E-value: 0.027
                    SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLell 42  
                    +p +l++++rrl +D++  VR Aa+e l
    EEA18489.1 1191 SPAILEAVIRRLeNDEKWYVRRAAIEAL 1218
                    799*********55***********976 PP

  == domain 9  score: 5.6 bits;  conditional E-value: 0.032
                    SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLell 42  
                    +p +l++++rrl +D+ + VR Aa+e +
    EEA18489.1 1225 SPNILEAVIRRLeNDENSYVRYAAIEAI 1252
                    799*********55***********976 PP

  == domain 10  score: 7.6 bits;  conditional E-value: 0.0075
                    SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLell 42  
                    +p +l++++rrl +D+++ V+ Aa+e l
    EEA18489.1 1259 SPAILEAVIRRLeNDEDSGVKRAAIEAL 1286
                    589*********56***********976 PP

  == domain 11  score: 3.0 bits;  conditional E-value: 0.21
                    SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLell 42  
                    +p +l++++rrl +D++  VR Aa++ l
    EEA18489.1 1361 SPALLEAVIRRLeNDEKWYVRRAAIKAL 1388
                    58899*******55**********9875 PP

  == domain 12  score: 5.8 bits;  conditional E-value: 0.028
                    SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrl.tDsspsVRdAaLell 42  
                    +p++ld+++ rl +D+++ VR Aa++ l
    EEA18489.1 1395 SPDILDAVICRLeNDEDSGVRRAAIKAL 1422
                    69999999999956**********9875 PP

  == domain 13  score: -0.6 bits;  conditional E-value: 2.8
                    SHHHHHHHHHHHH CS
  Cohesin_HEAT   16 apevldtiarrlt 28  
                    +p +l++++rrl+
    EEA18489.1 1429 SPAILEAVIRRLE 1441
                    699********95 PP

>> HEAT_PBS  PBS lyase HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.0     0.014       8.6       1      20 [.     937     958 ..     937     965 .. 0.71
   2 !    8.7   0.1    0.0053       3.3       1      21 [.     971     993 ..     971     999 .. 0.76
   3 ?    6.5   0.1     0.027        17       1      19 [.    1005    1025 ..    1005    1033 .. 0.69
   4 ?    6.1   0.0     0.035        21       1      26 [.    1039    1066 ..    1039    1067 .. 0.83
   5 ?    7.7   0.2     0.011       6.6       1      25 [.    1073    1099 ..    1073    1101 .. 0.80
   6 ?    1.5   0.0       1.1   6.8e+02       1      13 [.    1108    1120 ..    1108    1136 .. 0.76
   7 ?    3.9   0.1      0.18   1.1e+02       1      25 [.    1142    1168 ..    1142    1170 .. 0.80
   8 ?    2.2   0.1      0.65     4e+02       1      10 [.    1176    1185 ..    1176    1204 .. 0.77
   9 ?    4.1   0.1      0.15        95       1      14 [.    1210    1223 ..    1210    1238 .. 0.71
  10 ?    5.7   0.1     0.049        30       1      26 [.    1244    1271 ..    1244    1272 .. 0.82
  11 ?    1.7   0.0      0.95   5.9e+02       1      11 [.    1278    1288 ..    1278    1303 .. 0.90
  12 ?    3.7   0.0      0.21   1.3e+02       1      16 [.    1312    1329 ..    1312    1340 .. 0.74
  13 ?    4.1   0.1      0.16        98       2      13 ..    1347    1358 ..    1346    1374 .. 0.75
  14 ?    4.6   0.0      0.11        69       1      12 [.    1380    1391 ..    1380    1403 .. 0.78
  15 ?    6.4   0.3     0.028        18       1      26 [.    1414    1441 ..    1414    1442 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.014
                 HHHHHHHHHHHCTS..GGGHHH CS
    HEAT_PBS   1 vRraAakaLgqlgd..eeaipa 20 
                 vRraA++aLg+     + +++a
  EEA18489.1 937 VRRAAVEALGTQSPwsPNILEA 958
                 9*********976656555554 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.0053
                 HHHHHHHHHHHCTS..GGGHHHH CS
    HEAT_PBS   1 vRraAakaLgqlgd..eeaipaL 21 
                 vRraA+kaLg+     +++++a 
  EEA18489.1 971 VRRAAIKALGTQSPwpPAILEAV 993
                 9*********9887766666655 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.027
                  HHHHHHHHHHHCTS..GGGHH CS
    HEAT_PBS    1 vRraAakaLgqlgd..eeaip 19  
                  +R+aA+kaLg+  +  ++ ++
  EEA18489.1 1005 IRHAAIKALGTQSSwsPALLE 1025
                  6*********99885533333 PP

  == domain 4  score: 6.1 bits;  conditional E-value: 0.035
                  HHHHHHHHHHHCTS..GGGHHHHHHHCT CS
    HEAT_PBS    1 vRraAakaLgqlgd..eeaipaLleaLq 26  
                  vR+ A+kaLg+     +++++a ++ L+
  EEA18489.1 1039 VRYTAIKALGTQSPwsPAILEAVIRRLE 1066
                  9*********998888888887777665 PP

  == domain 5  score: 7.7 bits;  conditional E-value: 0.011
                  HHHHHHHHHHHCTS..GGGHHHHHHHC CS
    HEAT_PBS    1 vRraAakaLgqlgd..eeaipaLleaL 25  
                  vRraA++aLg+     +++++a ++ L
  EEA18489.1 1073 VRRAAIEALGTQSPwsPAILEAVIRRL 1099
                  9*********98887777777766655 PP

  == domain 6  score: 1.5 bits;  conditional E-value: 1.1
                  HHHHHHHHHHHCT CS
    HEAT_PBS    1 vRraAakaLgqlg 13  
                  vR+ A+ aLg+  
  EEA18489.1 1108 VRHTAINALGTQS 1120
                  8*********865 PP

  == domain 7  score: 3.9 bits;  conditional E-value: 0.18
                  HHHHHHHHHHHCTS..GGGHHHHHHHC CS
    HEAT_PBS    1 vRraAakaLgqlgd..eeaipaLleaL 25  
                  vRraA+ aL +     +++++a ++ L
  EEA18489.1 1142 VRRAAINALSTQSPwsPAILEAVIRRL 1168
                  9********998887777777777666 PP

  == domain 8  score: 2.2 bits;  conditional E-value: 0.65
                  HHHHHHHHHH CS
    HEAT_PBS    1 vRraAakaLg 10  
                  vRraA++aL 
  EEA18489.1 1176 VRRAAIEALD 1185
                  9*******96 PP

  == domain 9  score: 4.1 bits;  conditional E-value: 0.15
                  HHHHHHHHHHHCTS CS
    HEAT_PBS    1 vRraAakaLgqlgd 14  
                  vRraA++aL +   
  EEA18489.1 1210 VRRAAIEALRTQSP 1223
                  9********98665 PP

  == domain 10  score: 5.7 bits;  conditional E-value: 0.049
                  HHHHHHHHHHHCTS..GGGHHHHHHHCT CS
    HEAT_PBS    1 vRraAakaLgqlgd..eeaipaLleaLq 26  
                  vR+aA++a+g+     +++++a ++ L+
  EEA18489.1 1244 VRYAAIEAIGTQSPwsPAILEAVIRRLE 1271
                  9*********998888888887777665 PP

  == domain 11  score: 1.7 bits;  conditional E-value: 0.95
                  HHHHHHHHHHH CS
    HEAT_PBS    1 vRraAakaLgq 11  
                  v raA++aLg+
  EEA18489.1 1278 VKRAAIEALGT 1288
                  78*******97 PP

  == domain 12  score: 3.7 bits;  conditional E-value: 0.21
                  HHHHHHHHHHHCTS..GG CS
    HEAT_PBS    1 vRraAakaLgqlgd..ee 16  
                  +R+aA+k Lg+  +  ++
  EEA18489.1 1312 IRYAAIKTLGTQSSwsPA 1329
                  6*********98775444 PP

  == domain 13  score: 4.1 bits;  conditional E-value: 0.16
                  HHHHHHHHHHCT CS
    HEAT_PBS    2 RraAakaLgqlg 13  
                  RraA++aLg+  
  EEA18489.1 1347 RRAAIEALGKQS 1358
                  9********965 PP

  == domain 14  score: 4.6 bits;  conditional E-value: 0.11
                  HHHHHHHHHHHC CS
    HEAT_PBS    1 vRraAakaLgql 12  
                  vRraA+kaL + 
  EEA18489.1 1380 VRRAAIKALSTQ 1391
                  9********875 PP

  == domain 15  score: 6.4 bits;  conditional E-value: 0.028
                  HHHHHHHHHHHCTS..GGGHHHHHHHCT CS
    HEAT_PBS    1 vRraAakaLgqlgd..eeaipaLleaLq 26  
                  vRraA+kaL +     +++++a ++ L+
  EEA18489.1 1414 VRRAAIKALSTQSLwsPAILEAVIRRLE 1441
                  9*********999988888888777665 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.1   0.1   4.6e-16   2.8e-13       1     163 [.     412     569 ..     412     572 .. 0.84

  Alignments for each domain:
  == domain 1  score: 50.1 bits;  conditional E-value: 4.6e-16
                 SCEEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-....-HCHHHCCCCTS--SSS-CCHHHHCCS.CCCEEEEEE-STT-SS-T CS
       NACHT   1 rlvilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgna.rsladllfsqlpepaapvsevwavllel.perlLlilDglDelvtdl 97 
                 r ++++G+aG+GKTtL +k++++  +++l ++ f+ +++++lr+l+  ++    +++ lf++  e    v++ ++  l +  +++L +lDglDe++   
  EEA18489.1 412 RRILIRGRAGVGKTTLCKKIVHDFLHQQLWADLFDRIIWIPLRRLKGMSDLdEFFRQELFKHEAERDCLVTKLRKTALDQtHKKTLWLLDGLDEVSGYR 510
                 679********************************************998877788888888888888888877766655167899**********855 PP

                 CH.........HHHHHCTTTTT--EEEEEEECCCHHHHCTTSSCE..EEEE--TCCHHHHHHHHCT CS
       NACHT  98 gqkekqpvrtlLselirkkllpeasllltvrpralrdleeqleeaivlevegfsesrrkqlvrkyf 163
                 ++     +   L+e+++  ll e  +++t+rp a++ l+ +  +   le  gf  +++++++ k  
  EEA18489.1 511 NP-----SGADLTEIFNS-LLNEDNVIITSRPHAVKLLGLTPFD-LELETVGFHLNQVQAYLAKAV 569
                 55.....77889999998.9999************554444334.488888999999999987765 PP

>> Adaptin_N  Adaptin N terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.5   0.0   1.8e-09   1.1e-06      28     370 ..     906    1360 ..     887    1381 .. 0.67
   2 ?    2.4   0.0     0.075        46     115     177 ..    1364    1423 ..    1357    1447 .. 0.74

  Alignments for each domain:
  == domain 1  score: 27.5 bits;  conditional E-value: 1.8e-09
                  HHHHHHHHCT---GHHHHHHHCCCC.SS-CHHHHHHHHHHHHHCTTSCCHHCCCCHHHHHHCCSSSHHHHHHHHHHHCCC--CCCHHHHHHHHHHHH CS
   Adaptin_N   28 kkliylialGedvsflffevvklva.skdfelKrlvYlylellaeesedlalLvtnslqkDlkdpnqlirglALrvLssirvpelaedlapaikkll 123 
                  kk++  +a+  ++sf +++++ +++  +d  ++r    +l   +  s++++  v+  l +D    ++ +r  A+++L++  +p    +l+  i++l 
  EEA18489.1  906 KKILRALAYRWHMSFNLMDITTNFMgDSDSNVRRAAVEALGTQSPWSPNILEAVIRRLEND---EDSGVRRAAIKALGTQ-SPWPPAILEAVIRQLE 998 
                  5555555555556665565555555555555666555555555555555444444444443...4445555555555542.2222223333333333 PP

                  T-SSHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHCTT-SSHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHH............HCS-HHH CS
   Adaptin_N  124 kdrspyvrkkAalailklykkdpdllrkqlveeikellsdkdpgvvlaAvalleeikkndrlllkllpklvrrLcnll............teldpwl 208 
                  + r++y+r +A+ a+ +  + +p ll+      i  l +d++  v ++A+++l     +      +l+  +rrL+n              ++ +pw 
  EEA18489.1  999 NNRDSYIRHAAIKALGTQSSWSPALLEA----VIRRLENDENSNVRYTAIKALGTQ-SPWSP--AILEAVIRRLENDKdsgvrraaiealGTQSPWS 1088
                  4555566666665555555555555322....233333556666666666665555.33333..455555555553335555555555555555555 PP

                  HHHHHHHHCC---SSHHHH.............................................................................. CS
   Adaptin_N  209 qvkiiklltrlarqepeer.............................................................................. 227 
                   +++  +++rl ++++  +                                                                              
  EEA18489.1 1089 PAILEAVIRRLEKNDETWDvrhtainalgtqspwspalleavirrlenntewnvrraainalstqspwspaileavirrlendedsgvrraaieald 1185
                  5555555555555555555555556666666666666666666666666666667778888888888888888888888888888889********* PP

                  .........................................HHHHHHHCGGCG.CSSCHHHHHHHHHCCHCCCCSTHHHCCHHCHHHHHH.SSCCTC CS
   Adaptin_N  228 .......................................skkellesllnllq.ssnnaVlletvnlivelapknelivlavnaLvrlls.skdenl 283 
                                                         s  ++le +  +l+   n +V ++++++i + +p +++   + +a +r l+ ++d ++
  EEA18489.1 1186 tksplspaileavirrlendekwyvrraaiealrtqspcS-PNILEAVIRRLEnDENSYVRYAAIEAIGTQSPWSPA---ILEAVIRRLEnDEDSGV 1278
                  ********************99999999998888765542.679999999999667788***********9998885...99****999999***** PP

                  HHHHHCHHHHHHHHXXTTTTTTTCCCCSXXTTSXHHHHHHHHHHHCCCXXTTTHHHHHHHHHHHTTSSXXHHHHHHHHHHHHHHHHH CS
   Adaptin_N  284 ryvaLrtllkivkkepkavqhldlkifllktdddvsirlkaldlllklvdesNvkeivkeLkkyvkevadedfksklvkaIgrlaek 370 
                  + +a+++l + +  + +a+   ++ i+ l++d+  +ir  a+ +l +  ++s   +i+k +  ++++  d d+++++++a+g+ + +
  EEA18489.1 1279 KRAAIEALGTKSPLS-PAIL--EIVIRQLENDEGFYIRYAAIKTLGT--QSSWSPAILKAMIHQLENNEDSDMRRAAIEALGKQSPW 1360
                  ************999.8885..7999*****************9864..4555689*********9999***********9976655 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.075
                  HHHHHHHHHT.-SSHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHCTT-SSHHHHHHHHHHHH CS
   Adaptin_N  115 lapaikkllk.drspyvrkkAalailklykkdpdllrkqlveeikellsdkdpgvvlaAvalle 177 
                  l++a+ + l+ d++ yvr++A+ a+ +    +pd+l       i  l +d+d gv +aA+++l 
  EEA18489.1 1364 LLEAVIRRLEnDEKWYVRRAAIKALSTQSLWSPDILDA----VICRLENDEDSGVRRAAIKALS 1423
                  555555555526666*******9999999999999633....45555599999***99999986 PP

>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.9   0.0   1.3e-10   7.8e-08      24     209 ..      36     290 ..      10     308 .. 0.74

  Alignments for each domain:
  == domain 1  score: 31.9 bits;  conditional E-value: 1.3e-10
                 EEEEE.TTEEEEEEEETTEEEEEEE--...SSHHHHHHHHHHHHHHHC.--SEEEEEEEEEES...STTT-TT-EEEEEE......EEESSSCCGCCTH CS
   PNP_UDP_1  24 pfgregrgfkfvtGtlkgkpvvivstG...iGkpnaavvaeirllkef.gvkaiiriGtaGgl...npdlkvGDvvipdd......ainfdgrsplygp 109
                 p+ +   +  + +G+l g+ +vi++      G++ aa   + r+   f +    +++G+ Gg+   n+d+++GDvv+++       +i++d++ +  g 
  EEA18489.1  36 PNPS-TDSNAYELGELDGHYIVITCLPvgvYGTVAAA-NVVSRMRSTFpRLQYGLMVGIGGGVpgkNNDIRLGDVVVSKPvgqhggVIQYDYGKTVKGG 132
                 3333.48889999999999999999997766888888.4444444455556677999***********************4444444777777777766 PP

                 HCC.......................................TCCCCTTSSEE--HHHHHHHHH.........CHHTTT...................T CS
   PNP_UDP_1 110 kee.......................................gqyfpdsydapadpelrallke.........aaealg...................i 141
                 k e                                       +  +  ++++ + ++l++ l+e                                  +
  EEA18489.1 133 KLEptgalnkppqtllthmsqleakrvtgsednlktimeealIRNPDIEARFSPPEQLTDFLFEssyhhaageD----TcekcdkerlvkrkpretrtP 227
                 666***************************************77777777777777777777776666443332....13444666777777888889* PP

                 TEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTBETTCTC CS
   PNP_UDP_1 142 kvhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArelgipfaairvvsdlaaggadaea 209
                  +h+G++a+++++  ++e ++rl  + g+ + eME+a +       ++p ++ir++ d+ + +  +++
  EEA18489.1 228 YIHYGLIASGNQVMKDSETRDRLALQHGILCFEMEAAGLMD-----ELPTLVIRGICDYCDSHKQKQW 290
                 ***********************************987643.....6788888888886665544444 PP

>> NLRC4_HD2  NLRC4 helical domain HD2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.0   0.1   5.1e-10   3.2e-07       1      82 [.     731     810 ..     731     839 .. 0.74

  Alignments for each domain:
  == domain 1  score: 31.0 bits;  conditional E-value: 5.1e-10
   NLRC4_HD2   1 HlsiQeFlAAlyvvlseeeeksevlkeflelekketkellsls.kkaldkalksknghldlflrFLfGLlsesnqrlleellg 82 
                 Hl++QeF+AA y++++ ++e+s+ l   l+    +++++ + s +k l++   + +g++d+f rF+ GLl    ++++  +l+
  EEA18489.1 731 HLTFQEFFAAQYFIRCWRSESSKLL-IYLKAGFARETSIAKISpEKFLREE--KYSGRYDVFWRFVTGLLYNIDKQQVCLFLE 810
                 ***********************66.4444444443244443434444444..56899************9888877777766 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.2   0.0   3.8e-10   2.4e-07      22     111 ..     413     502 ..     401     544 .. 0.72

  Alignments for each domain:
  == domain 1  score: 30.2 bits;  conditional E-value: 3.8e-10
                 EEEEEESTTSSHHHHHHHHCCSH..CCCCC.CBTEEEEEEEESXXHHHHHHHXXHHHHHCCCTTSSSS-STTSHHHHHHHHCCCTTEEEEEEE CS
      NB-ARC  22 vvalvGmgGvGKttlakqilnks..deveg.rFdsvawvvvsktdkseeiletilkeLslseddleekeeveslkrklvrlLltkrfllvlDD 111
                  + + G++GvGKttl k+i++++  +++    Fd+++w+ + +    +++ e+  +eL ++e++++   ++  +k+ l +   +k++l +lD 
  EEA18489.1 413 RILIRGRAGVGKTTLCKKIVHDFlhQQLWAdLFDRIIWIPLRRLKGMSDLDEFFRQELFKHEAERDCLVTKL-RKTALDQT--HKKTLWLLDG 502
                 57899****************96335554459**************************99988887777666.66666664..5578888764 PP

>> CO_deh_flav_C  CO dehydrogenase flavoprotein C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0     0.072        44      37      74 ..     929     966 ..     911     977 .. 0.86
   2 ?    0.8   0.0      0.92   5.7e+02      45      74 ..    1005    1034 ..     999    1038 .. 0.86
   3 ?    1.3   0.0       0.6   3.7e+02      45      74 ..    1039    1068 ..    1035    1072 .. 0.89
   4 ?    1.3   0.0      0.61   3.8e+02      45      73 ..    1073    1101 ..    1069    1107 .. 0.89
   5 ?    2.1   0.0      0.35   2.2e+02      45      76 ..    1108    1139 ..    1102    1148 .. 0.87
   6 ?    0.6   0.0       1.1   6.5e+02      46      74 ..    1143    1171 ..    1137    1182 .. 0.85
   7 ?   -2.5   0.0       9.8     6e+03      45      74 ..    1210    1239 ..    1205    1242 .. 0.86
   8 ?    2.9   0.0       0.2   1.3e+02      44      74 ..    1243    1273 ..    1238    1284 .. 0.89
   9 ?    3.0   0.0      0.19   1.2e+02      45      74 ..    1346    1375 ..    1313    1386 .. 0.91
  10 ?   -1.6   0.0       4.8     3e+03      45      74 ..    1414    1443 ..    1392    1448 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.072
                    EESSSSS-EE-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C  37 fggvaptpvraekaeaaLiGkplseelleeaakaleee 74 
                    f+g ++  vr  ++ea+ + +p+s ++le+++++le++
     EEA18489.1 929 FMGDSDSNVRRAAVEALGTQSPWSPNILEAVIRRLEND 966
                    666677789999***********************987 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.92
                     EE-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C   45 vraekaeaaLiGkplseelleeaakaleee 74  
                     +r  +++a+ + +++s +lle+++++le++
     EEA18489.1 1005 IRHAAIKALGTQSSWSPALLEAVIRRLEND 1034
                     6778888889999**************987 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.6
                     EE-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C   45 vraekaeaaLiGkplseelleeaakaleee 74  
                     vr ++++a+ + +p+s ++le+++++le++
     EEA18489.1 1039 VRYTAIKALGTQSPWSPAILEAVIRRLEND 1068
                     78899999999***************9987 PP

  == domain 4  score: 1.3 bits;  conditional E-value: 0.61
                     EE-HHHHHHHTTSBSSHHHHHHHHHHHHT CS
  CO_deh_flav_C   45 vraekaeaaLiGkplseelleeaakalee 73  
                     vr  ++ea+ + +p+s ++le+++++le+
     EEA18489.1 1073 VRRAAIEALGTQSPWSPAILEAVIRRLEK 1101
                     6778899999***************9987 PP

  == domain 5  score: 2.1 bits;  conditional E-value: 0.35
                     EE-HHHHHHHTTSBSSHHHHHHHHHHHHTTCH CS
  CO_deh_flav_C   45 vraekaeaaLiGkplseelleeaakaleeels 76  
                     vr +++ a+ + +p+s +lle+++++le++ +
     EEA18489.1 1108 VRHTAINALGTQSPWSPALLEAVIRRLENNTE 1139
                     677888999999***************98765 PP

  == domain 6  score: 0.6 bits;  conditional E-value: 1.1
                     E-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C   46 raekaeaaLiGkplseelleeaakaleee 74  
                     r  ++ a+ + +p+s ++le+++++le++
     EEA18489.1 1143 RRAAINALSTQSPWSPAILEAVIRRLEND 1171
                     666778888999**************987 PP

  == domain 7  score: -2.5 bits;  conditional E-value: 9.8
                     EE-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C   45 vraekaeaaLiGkplseelleeaakaleee 74  
                     vr  ++ea+ + +p s ++le+++++le++
     EEA18489.1 1210 VRRAAIEALRTQSPCSPNILEAVIRRLEND 1239
                     67788899999999999********99987 PP

  == domain 8  score: 2.9 bits;  conditional E-value: 0.2
                     -EE-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C   44 pvraekaeaaLiGkplseelleeaakaleee 74  
                      vr  ++ea  + +p+s ++le+++++le++
     EEA18489.1 1243 YVRYAAIEAIGTQSPWSPAILEAVIRRLEND 1273
                     6889999*********************987 PP

  == domain 9  score: 3.0 bits;  conditional E-value: 0.19
                     EE-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C   45 vraekaeaaLiGkplseelleeaakaleee 74  
                     +r  ++ea+ + +p+s +lle+++++le++
     EEA18489.1 1346 MRRAAIEALGKQSPWSPALLEAVIRRLEND 1375
                     67788999999****************987 PP

  == domain 10  score: -1.6 bits;  conditional E-value: 4.8
                     EE-HHHHHHHTTSBSSHHHHHHHHHHHHTT CS
  CO_deh_flav_C   45 vraekaeaaLiGkplseelleeaakaleee 74  
                     vr  +++a+ + + +s ++le+++++le+e
     EEA18489.1 1414 VRRAAIKALSTQSLWSPAILEAVIRRLENE 1443
                     56667778888899999*******999986 PP

>> Vac14_Fab1_bd  Vacuolar 14 Fab1-binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.0      0.54   3.3e+02      29      51 ..     923     945 ..     915     979 .. 0.71
   2 ?    4.0   0.0      0.12        75      25      51 ..    1020    1047 ..    1005    1077 .. 0.80
   3 ?    0.4   0.0       1.6     1e+03      27      51 ..    1056    1081 ..    1047    1086 .. 0.80
   4 ?    1.1   0.0         1   6.3e+02      24      51 ..    1156    1184 ..    1142    1188 .. 0.74
   5 ?    6.6   0.0     0.019        12      19      51 ..    1219    1252 ..    1209    1283 .. 0.83
   6 ?   -0.1   0.0       2.3   1.4e+03      71      88 ..    1401    1418 ..    1379    1423 .. 0.75

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.54
  Vac14_Fab1_bd  29 vkpvlkcfsDkdsrvRyyacEsl 51 
                    +++  + + D+ds vR  a+E+l
     EEA18489.1 923 MDITTNFMGDSDSNVRRAAVEAL 945
                    44444555666666666666655 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.12
  Vac14_Fab1_bd   25 leeivkpvlkcf.sDkdsrvRyyacEsl 51  
                        +++ v++ + +D++s vRy+a+ +l
     EEA18489.1 1020 SPALLEAVIRRLeNDENSNVRYTAIKAL 1047
                     556778888766369999******9987 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 1.6
  Vac14_Fab1_bd   27 eivkpvlkcf.sDkdsrvRyyacEsl 51  
                      i++ v++ + +Dkds vR  a+E+l
     EEA18489.1 1056 AILEAVIRRLeNDKDSGVRRAAIEAL 1081
                     67888887663699999999999987 PP

  == domain 4  score: 1.1 bits;  conditional E-value: 1
  Vac14_Fab1_bd   24 yleeivkpvlkcf.sDkdsrvRyyacEsl 51  
                         i++ v++ + +D+ds vR  a+E+l
     EEA18489.1 1156 WSPAILEAVIRRLeNDEDSGVRRAAIEAL 1184
                     55678888887663689999999999987 PP

  == domain 5  score: 6.6 bits;  conditional E-value: 0.019
  Vac14_Fab1_bd   19 kkikeyleeivkpvlkcf.sDkdsrvRyyacEsl 51  
                     ++ +++  +i++ v++ + +D++s vRy a+E++
     EEA18489.1 1219 RTQSPCSPNILEAVIRRLeNDENSYVRYAAIEAI 1252
                     456788999****999873699999*******86 PP

  == domain 6  score: -0.1 bits;  conditional E-value: 2.3
  Vac14_Fab1_bd   71 dalvklvaDsdesvksga 88  
                      ++++l  D+d+ v+++a
     EEA18489.1 1401 AVICRLENDEDSGVRRAA 1418
                     467999999999999886 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0         9   5.6e+03      54      83 ..     273     307 ..     267     329 .. 0.72
   2 !   15.1   0.0   3.6e-05     0.022      20      63 ..     407     445 ..     395     532 .. 0.66
   3 ?   -0.9   4.7       3.1   1.9e+03      80      88 ..    1163    1171 ..     957    1459 .. 0.76

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 9
      AAA_16  54 iflrgkcdqlesa.....ipysalaqalareellr 83 
                 +++rg cd ++s       py+a++ a+ ++ ll 
  EEA18489.1 273 LVIRGICDYCDSHkqkqwQPYAAFTAAAYAKLLLS 307
                 56778888884444557899999888776655555 PP

  == domain 2  score: 15.1 bits;  conditional E-value: 3.6e-05
      AAA_16  20 rsgrpelvllsGesGvGKsslvrellralekdggiflrgkcdql 63 
                 r  rp+ +l++G +GvGK++l +++ + +  +     + ++d +
  EEA18489.1 407 RNARPRRILIRGRAGVGKTTLCKKIVHDFLHQ-----QLWADLF 445
                 5567899***************9998876666.....3333333 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 3.1
      AAA_16   80 ellrqllde 88  
                   ++r l+++
  EEA18489.1 1163 AVIRRLEND 1171
                  333333333 PP

>> EPL1  Enhancer of polycomb-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0       4.6   2.8e+03     140     156 ..     949     965 ..     931     966 .. 0.84
   2 ?    1.4   0.0      0.62   3.8e+02     140     156 ..    1085    1101 ..     990    1102 .. 0.72
   3 ?   -0.6   0.0       2.4   1.5e+03     139     156 ..    1153    1170 ..    1117    1171 .. 0.69
   4 ?    7.0   0.0     0.011       6.9     121     156 ..    1203    1238 ..    1202    1239 .. 0.91
   5 ?    1.1   0.0      0.77   4.8e+02     140     156 ..    1290    1306 ..    1252    1307 .. 0.73
   6 ?    0.4   0.0       1.2   7.7e+02     121     156 ..    1373    1408 ..    1372    1443 .. 0.50

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 4.6
        EPL1 140 ekisediFEivmdrlEk 156
                 ++ s++i E v+ rlE+
  EEA18489.1 949 SPWSPNILEAVIRRLEN 965
                 7889************7 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.62
        EPL1  140 ekisediFEivmdrlEk 156 
                  ++ s++i E v+ rlEk
  EEA18489.1 1085 SPWSPAILEAVIRRLEK 1101
                  56677777777777776 PP

  == domain 3  score: -0.6 bits;  conditional E-value: 2.4
        EPL1  139 vekisediFEivmdrlEk 156 
                   ++ s++i E v+ rlE+
  EEA18489.1 1153 QSPWSPAILEAVIRRLEN 1170
                  277888999999999986 PP

  == domain 4  score: 7.0 bits;  conditional E-value: 0.011
        EPL1  121 EeDekWLeelnekrkkegvekisediFEivmdrlEk 156 
                  E DekW+ +  +     + +++s++i E v+ rlE+
  EEA18489.1 1203 ENDEKWYVRRAAIEALRTQSPCSPNILEAVIRRLEN 1238
                  89*****999998778888****************7 PP

  == domain 5  score: 1.1 bits;  conditional E-value: 0.77
        EPL1  140 ekisediFEivmdrlEk 156 
                  +++s++i Eiv+ +lE+
  EEA18489.1 1290 SPLSPAILEIVIRQLEN 1306
                  78899999999999996 PP

  == domain 6  score: 0.4 bits;  conditional E-value: 1.2
        EPL1  121 EeDekWLeelnekrkkegvekisediFEivmdrlEk 156 
                  E DekW+ +  + +  ++ +  s+di   v+ rlE+
  EEA18489.1 1373 ENDEKWYVRRAAIKALSTQSLWSPDILDAVICRLEN 1408
                  567777766666644444444455555555555543 PP

>> DNA_alkylation  DNA alkylation repair enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.68   4.2e+02      50      90 ..    1022    1061 ..    1002    1071 .. 0.69
   2 !   14.4   1.7   3.8e-05     0.024      36     210 ..    1075    1249 ..    1066    1252 .. 0.84
   3 !    7.8   0.3    0.0039       2.4      44     143 ..    1322    1421 ..    1275    1430 .. 0.83

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.68
  DNA_alkylation   50 eelqelaeeLwksperEerllAldlltqakkklaeadlely 90  
                      + l++++++L ++++   r++A++ l  + ++   a+le +
      EEA18489.1 1022 ALLEAVIRRLENDENSNVRYTAIKALGTQSPWSP-AILEAV 1061
                      456788999999999***********88777744.444443 PP

  == domain 2  score: 14.4 bits;  conditional E-value: 3.8e-05
  DNA_alkylation   36 rklakeffkelkle.eelqelaeeLwkspe.rEerllAldlltqakkklaeadlelyeklvetinnWdlvDslaskivgalladkperrdllk 126 
                      r+ +  + ++ + + ++l++++++L k++e  + r++A+  l  + ++ ++a+le + + +e   +W++  ++++++ ++  ++    +++++
      EEA18489.1 1075 RAAIEALGTQSPWSpAILEAVIRRLEKNDEtWDVRHTAINALGTQSPW-SPALLEAVIRRLENNTEWNVRRAAINALSTQSPWSPAILEAVIR 1166
                      44444444444444577888999999999889**********888877.5588**************************999998888999** PP

  DNA_alkylation  127 eWaksenlWerRaAivatlklikktdlellleiaeelladkedfiqkAiGwaLrelsktdpdlveeFlekhakrmprlslreAi 210 
                      ++ ++e+  +rRaAi a l  +     + l +++ +l +d+++ ++ A   aLr  s   p+ +e+ + + ++   + ++  Ai
      EEA18489.1 1167 RLENDEDSGVRRAAIEA-LDTKSPLSPAILEAVIRRLENDEKWYVRRAAIEALRTQSPCSPNILEAVIRRLENDENSYVRYAAI 1249
                      ***************98.688899*********************************999999998888866655555555555 PP

  == domain 3  score: 7.8 bits;  conditional E-value: 0.0039
  DNA_alkylation   44 kelkle.eelqelaeeLwksperEerllAldlltqakkklaeadlelyeklvetinnWdlvDslaskivgalladkperrdllkeWaksenlW 135 
                      ++ + + ++l++ + +L +++  ++r +A++ l ++ ++ ++a+le + + +e  ++W +  ++++++ ++ l++ +  ++++ ++ ++e+  
      EEA18489.1 1322 TQSSWSpAILKAMIHQLENNEDSDMRRAAIEALGKQSPW-SPALLEAVIRRLENDEKWYVRRAAIKALSTQSLWSPDILDAVICRLENDEDSG 1413
                      444444567888999999999999999999999887777.55779999999999999988888889999999999777788889999999999 PP

  DNA_alkylation  136 erRaAiva 143 
                      +rRaAi a
      EEA18489.1 1414 VRRAAIKA 1421
                      99999976 PP

>> Arm  Armadillo/beta-catenin-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0       2.1   1.3e+03      20      37 ..     929     946 ..     923     946 .. 0.87
   2 ?    2.2   0.0      0.32     2e+02      10      37 ..     952     980 ..     951     980 .. 0.90
   3 ?   -1.9   0.0       6.6   4.1e+03      14      36 ..     990    1013 ..     989    1014 .. 0.73
   4 ?   -0.1   0.0       1.8   1.1e+03      14      37 ..    1058    1082 ..    1057    1082 .. 0.83
   5 ?   -1.5   0.0       4.7   2.9e+03      14      36 ..    1161    1184 ..    1160    1184 .. 0.81
   6 ?    0.0   0.0       1.6     1e+03      14      37 ..    1263    1287 ..    1262    1287 .. 0.84
   7 ?    2.1   0.0      0.35   2.1e+02      14      37 ..    1331    1355 ..    1329    1356 .. 0.90
   8 ?    1.9   0.0       0.4   2.4e+02       6      37 ..    1391    1423 ..    1389    1424 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 2.1
                 HTTTSSHHHHHHHHHHHH CS
         Arm  20 LLssedeevqeeAawALs 37 
                 ++ + d +v+++A+ AL+
  EEA18489.1 929 FMGDSDSNVRRAAVEALG 946
                 566899**********96 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.32
                 HTTHHHHHHHHTT.TSSHHHHHHHHHHHH CS
         Arm  10 eaGavppLvrLLs.sedeevqeeAawALs 37 
                 + +++++ +r L+ +ed +v+++A  AL+
  EEA18489.1 952 SPNILEAVIRRLEnDEDSGVRRAAIKALG 980
                 5799999*****************99986 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 6.6
                  HHHHHHHTT.TSSHHHHHHHHHHH CS
         Arm   14 vppLvrLLs.sedeevqeeAawAL 36  
                  +++ +r L+ + d  ++++A  AL
  EEA18489.1  990 LEAVIRQLEnNRDSYIRHAAIKAL 1013
                  788899999777777777777666 PP

  == domain 4  score: -0.1 bits;  conditional E-value: 1.8
                  HHHHHHHTT.TSSHHHHHHHHHHHH CS
         Arm   14 vppLvrLLs.sedeevqeeAawALs 37  
                  +++ +r L+ ++d +v+++A  AL+
  EEA18489.1 1058 LEAVIRRLEnDKDSGVRRAAIEALG 1082
                  56677778889*********99996 PP

  == domain 5  score: -1.5 bits;  conditional E-value: 4.7
                  HHHHHHHTT.TSSHHHHHHHHHHH CS
         Arm   14 vppLvrLLs.sedeevqeeAawAL 36  
                  +++ +r L+ +ed +v+++A  AL
  EEA18489.1 1161 LEAVIRRLEnDEDSGVRRAAIEAL 1184
                  566777788899*******98887 PP

  == domain 6  score: 0.0 bits;  conditional E-value: 1.6
                  HHHHHHHTT.TSSHHHHHHHHHHHH CS
         Arm   14 vppLvrLLs.sedeevqeeAawALs 37  
                  +++ +r L+ +ed +v+++A  AL+
  EEA18489.1 1263 LEAVIRRLEnDEDSGVKRAAIEALG 1287
                  56677778889*********99996 PP

  == domain 7  score: 2.1 bits;  conditional E-value: 0.35
                  HHHHHHHTT.TSSHHHHHHHHHHHH CS
         Arm   14 vppLvrLLs.sedeevqeeAawALs 37  
                  +++ ++ L+ +ed +++++A  AL+
  EEA18489.1 1331 LKAMIHQLEnNEDSDMRRAAIEALG 1355
                  7788999**************9997 PP

  == domain 8  score: 1.9 bits;  conditional E-value: 0.4
                  HHHHHTTHHHHHHHHTT.TSSHHHHHHHHHHHH CS
         Arm    6 davieaGavppLvrLLs.sedeevqeeAawALs 37  
                  + +++  ++++ +  L+ +ed +v+++A  ALs
  EEA18489.1 1391 QSLWSPDILDAVICRLEnDEDSGVRRAAIKALS 1423
                  567888899999999999**********99997 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   4.3e-06    0.0026       8     123 ..     414     530 ..     408     545 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 4.3e-06
      AAA_22   8 lvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelkaerlsseell.ealeqalrarav.ielliiDEaqhlr 104
                 +++ G +G+GKTtl++++++ +  ++  ++  ++++ + l  +++ +dl + + ++l   ++a    ++++l ++l++ + ++   + l ++D  + ++
  EEA18489.1 414 ILIRGRAGVGKTTLCKKIVHDFLHQQLWADLFDRIIWIPLRRLKGMSDLDEFFRQELFK-HEA----ERDCLvTKLRKTALDQTHkKTLWLLDGLDEVS 507
                 7899******************9888888899999999999999999999999999993.333....5566658888777777767899********96 PP

      AAA_22 105 ..s...eealeeL.rsllnlsrkgv 123
                   +    + l+e+  slln  +++v
  EEA18489.1 508 gyRnpsGADLTEIfNSLLN--EDNV 530
                 6614554444444477777..5554 PP

>> Nore1-SARAH  Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       4.3   2.6e+03       5      22 ..    1022    1039 ..    1020    1042 .. 0.83
   2 ?   -1.4   0.0       3.8   2.3e+03       5      21 ..    1159    1175 ..    1157    1178 .. 0.82
   3 ?    1.0   0.0      0.64     4e+02       4      23 ..    1192    1211 ..    1191    1212 .. 0.88
   4 ?   -1.2   0.0       3.2     2e+03       6      23 ..    1228    1245 ..    1225    1245 .. 0.89
   5 ?   -1.5   0.0         4   2.5e+03       5      20 ..    1261    1276 ..    1259    1280 .. 0.82
   6 ?    0.9   0.0      0.69   4.2e+02       5      24 ..    1363    1382 ..    1361    1383 .. 0.88
   7 ?    5.4   0.0     0.028        17       4      22 ..    1430    1448 ..    1428    1452 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 4.3
  Nore1-SARAH    5 PELqnFLriLeeEEeeei 22  
                   ++L+  +r Le  E+  +
   EEA18489.1 1022 ALLEAVIRRLENDENSNV 1039
                   789********9998766 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 3.8
  Nore1-SARAH    5 PELqnFLriLeeEEeee 21  
                   ++L+  +r Le  E+  
   EEA18489.1 1159 AILEAVIRRLENDEDSG 1175
                   78*********999865 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 0.64
  Nore1-SARAH    4 lPELqnFLriLeeEEeeeiq 23  
                    ++L+  +r Le  E+ +++
   EEA18489.1 1192 PAILEAVIRRLENDEKWYVR 1211
                   579*************9997 PP

  == domain 4  score: -1.2 bits;  conditional E-value: 3.2
  Nore1-SARAH    6 ELqnFLriLeeEEeeeiq 23  
                   +L+  +r Le  E+ +++
   EEA18489.1 1228 ILEAVIRRLENDENSYVR 1245
                   69999********99985 PP

  == domain 5  score: -1.5 bits;  conditional E-value: 4
  Nore1-SARAH    5 PELqnFLriLeeEEee 20  
                   ++L+  +r Le  E+ 
   EEA18489.1 1261 AILEAVIRRLENDEDS 1276
                   78*********99986 PP

  == domain 6  score: 0.9 bits;  conditional E-value: 0.69
  Nore1-SARAH    5 PELqnFLriLeeEEeeeiqq 24  
                   ++L+  +r Le  E+ ++++
   EEA18489.1 1363 ALLEAVIRRLENDEKWYVRR 1382
                   78*************99975 PP

  == domain 7  score: 5.4 bits;  conditional E-value: 0.028
  Nore1-SARAH    4 lPELqnFLriLeeEEeeei 22  
                    ++L+  +r Le EE+ e+
   EEA18489.1 1430 PAILEAVIRRLENEEDSEV 1448
                   579*************998 PP

>> Cnd3  Nuclear condensing complex subunits, C-term domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0     0.062        38      25      87 ..     988    1047 ..     976    1050 .. 0.74
   2 ?   -0.2   0.0      0.75   4.6e+02      39      56 ..    1070    1087 ..    1043    1184 .. 0.59
   3 ?    2.4   0.0      0.12        73     115     146 ..    1325    1356 ..    1223    1357 .. 0.85
   4 ?   -2.1   0.0       2.7   1.7e+03      30      59 ..    1368    1397 ..    1362    1403 .. 0.71
   5 ?    0.6   0.0      0.43   2.6e+02      26      64 ..    1398    1436 ..    1383    1455 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.062
                  HHHHHTHHHHHC-SSHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHS-HHHHHHHHHHH CS
        Cnd3   25 slleslilpavrskeaairelglkcLglfclldkklakenlklflqalskgneelkiialkai 87  
                  ++le  i++  ++++  ir +++k+Lg+ +  +  l +  ++ + +    +n++++ +a+ka+
  EEA18489.1  988 AILEAVIRQLENNRDSYIRHAAIKALGTQSSWSPALLEAVIRRLEND---ENSNVRYTAIKAL 1047
                  57777777777788*************99988888777666555432...2456777777765 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.75
                  SHHHHHHHHHHHHHHHTT CS
        Cnd3   39 eaairelglkcLglfcll 56  
                  +  +r++++++Lg+ +  
  EEA18489.1 1070 DSGVRRAAIEALGTQSPW 1087
                  556666666666655433 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.12
                  ....HHHHHHHHHHC-TT-HHHHHHHHHHHHH CS
        Cnd3  115 essksllkllykaLdsednpelqaiaaeglcK 146 
                  + s  +lk ++++L+++++++++ +a+e+l K
  EEA18489.1 1325 SWSPAILKAMIHQLENNEDSDMRRAAIEALGK 1356
                  45667899999999988889999999998865 PP

  == domain 4  score: -2.1 bits;  conditional E-value: 2.7
                  THHHHHC-SSHHHHHHHHHHHHHHHTT-HH CS
        Cnd3   30 lilpavrskeaairelglkcLglfclldkk 59  
                   i++  + ++  +r++++k+L++ +l + +
  EEA18489.1 1368 VIRRLENDEKWYVRRAAIKALSTQSLWSPD 1397
                  4444444447889********999998766 PP

  == domain 5  score: 0.6 bits;  conditional E-value: 0.43
                  HHHHTHHHHHC-SSHHHHHHHHHHHHHHHTT-HHHHHHH CS
        Cnd3   26 lleslilpavrskeaairelglkcLglfclldkklaken 64  
                  +l+  i++  + ++  +r++++k+L++ +l +  + +  
  EEA18489.1 1398 ILDAVICRLENDEDSGVRRAAIKALSTQSLWSPAILEAV 1436
                  7788888888888999************99988776655 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   0.00012     0.075       1      92 [.     414     527 ..     414     545 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 0.00012
                 EEEESSTTSSHHHHHHHHHHHH..........T....HEEEEEETTTCSSS........STTHHHHHHHHHHHHHHHTS.....TSEEEEEETGGGHHH CS
         AAA   1 vllyGppGtGKTllakavakel..........g....vefleisgsellsk........yvgesekkirelfkeakeka.....kpsilfiDEidalak 72 
                 +l+ G  G+GKT+l+k +++++          +    +++ +++g++ l++        +  e+   + +l k+    a     k++  ++D +d++ +
  EEA18489.1 414 ILIRGRAGVGKTTLCKKIVHDFlhqqlwadlfDriiwIPLRRLKGMSDLDEffrqelfkHEAERDCLVTKLRKT----AldqthKKTLWLLDGLDEVSG 508
                 57889****************54433333333133446677777777776666665433334444445555555....334446679999999999999 PP

                 HHTTCCCHHHHHHHHHHHHH CS
         AAA  73 srsgseseeeervvnqLlte 92 
                  r + +  + +++ n Ll+e
  EEA18489.1 509 YR-NPSGADLTEIFNSLLNE 527
                 99.67788888889988876 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   0.00013     0.081       1      22 [.     413     434 ..     413     441 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 0.00013
                 EEEEE--TTSSHHHHHHHHHHH CS
    NTPase_1   1 kvfiTGppGvGKtTlvkkvlel 22 
                 +++i G+ GvGKtTl+kk+++ 
  EEA18489.1 413 RILIRGRAGVGKTTLCKKIVHD 434
                 5899**************9875 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   0.00037      0.23       1      33 [.     414     442 ..     414     515 .. 0.51

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00037
      AAA_18   1 IlltGtpGvGKttlakeLskrlgfgvnlrdvak 33 
                 Il+ G +GvGKttl+k +       + ++++++
  EEA18489.1 414 ILIRGRAGVGKTTLCKKIVHD----FLHQQLWA 442
                 8999*************9554....22222222 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   0.00047      0.29       1      25 [.     414     438 ..     414     464 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00047
  RNA_helicase   1 iwlyGpsgeGKStlakeLakallkk 25 
                   i++ G++g+GK+tl+k++++++l +
    EEA18489.1 414 ILIRGRAGVGKTTLCKKIVHDFLHQ 438
                   6899****************99954 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0    0.0007      0.43       5      59 ..     414     469 ..     410     534 .. 0.55

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.0007
      AAA_14   5 lvitGaRrvGKTtllkqlikell......vkkesilyinldderd....kkladpekllelilek 59 
                 ++i+G   vGKTtl+k+++++ l         ++i+ i l + +     +         e+++++
  EEA18489.1 414 ILIRGRAGVGKTTLCKKIVHDFLhqqlwaDLFDRIIWIPLRRLKGmsdlD---------EFFRQE 469
                 7899***************9999555554334555555555433322220.........222222 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00067      0.42      23      93 ..     414     491 ..     402     512 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00067
    ATPase_2  23 yfiYGpegsGKtaLlkeiienledkdk.....yviyyialre.esiskldefie.....eeeekkklekal.giavpkaelee 93 
                 ++i G+ g+GKt+L k+i+   ++++      ++i  i+lr+ +  s ldef++           ++e+    ++++k++l++
  EEA18489.1 414 ILIRGRAGVGKTTLCKKIVHDFLHQQLwadlfDRIIWIPLRRlKGMSDLDEFFRqelfkH-----EAERDClVTKLRKTALDQ 491
                 6899****************9988776777887777777776255788999988544332.....333322144444444444 PP

>> AAA_17  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   0.1    0.0047       2.9       2      19 ..     418     435 ..     417     512 .. 0.84
   2 ?   -2.3   0.0       8.8   5.5e+03      46      87 ..    1165    1206 ..    1161    1256 .. 0.61
   3 ?   -0.8   0.0         3   1.9e+03      44      87 ..    1333    1376 ..    1323    1422 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.0047
                 E-TTSSHHHHHHHHHHHH CS
      AAA_17   2 GgPGsGKgtqceklveky 19 
                 G  G+GK+t+c+k+v+++
  EEA18489.1 418 GRAGVGKTTLCKKIVHDF 435
                 567************986 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 8.8
                  HCTSHHHHHHHHHHHHHHHHHHHHHSSEEEEEE-SEEEETTE CS
      AAA_17   46 mrklpleekkelqkeaaekiaeeakkkgvlvdghprikeqag 87  
                  +r+l+++e+  +++ a+e++  ++  + ++++   r  e+++
  EEA18489.1 1165 IRRLENDEDSGVRRAAIEALDTKSPLSPAILEAVIRRLENDE 1206
                  556666777777777777777666555566655555444443 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 3
                  HHHCTSHHHHHHHHHHHHHHHHHHHHHSSEEEEEE-SEEEETTE CS
      AAA_17   44 demrklpleekkelqkeaaekiaeeakkkgvlvdghprikeqag 87  
                    +++l+++e+ ++++ a+e++ +++  + +l++   r  e+++
  EEA18489.1 1333 AMIHQLENNEDSDMRRAAIEALGKQSPWSPALLEAVIRRLENDE 1376
                  45668999999999999999999998777788777777666655 PP

>> PduV-EutP  Ethanolamine utilisation - propanediol utilisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   0.00069      0.43       2      26 ..     412     436 ..     411     440 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00069
   PduV-EutP   2 kkilliGkvgsGKttLtqalkgeel 26 
                 ++il+ G+ g+GKttL++++ ++ l
  EEA18489.1 412 RRILIRGRAGVGKTTLCKKIVHDFL 436
                 68999*************9977655 PP

>> API5  Apoptosis inhibitory protein 5 (API5)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0       0.1        62      68      85 ..     964     981 ..     951    1050 .. 0.61
   2 ?   -4.0   0.1       7.6   4.7e+03      69      83 ..    1067    1081 ..    1057    1084 .. 0.82
   3 ?   -1.9   0.0       1.7   1.1e+03      69      84 ..    1170    1185 ..    1158    1252 .. 0.74
   4 ?    2.3   0.1     0.091        57      61      85 ..    1399    1424 ..    1394    1440 .. 0.79

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.1
        API5  68 iedddlgirkqAikdLps 85 
                  +d+d g+r++Aik+L +
  EEA18489.1 964 ENDEDSGVRRAAIKALGT 981
                 459999********9865 PP

  == domain 2  score: -4.0 bits;  conditional E-value: 7.6
        API5   69 edddlgirkqAikdL 83  
                  +d+d g+r++Ai +L
  EEA18489.1 1067 NDKDSGVRRAAIEAL 1081
                  699*********988 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 1.7
        API5   69 edddlgirkqAikdLp 84  
                  +d+d g+r++Ai +L 
  EEA18489.1 1170 NDEDSGVRRAAIEALD 1185
                  5899999999998874 PP

  == domain 4  score: 2.3 bits;  conditional E-value: 0.091
        API5   61 idaqlD.LiedddlgirkqAikdLps 85  
                  +da +  L +d+d g+r++Aik+L +
  EEA18489.1 1399 LDAVICrLENDEDSGVRRAAIKALST 1424
                  555554144699***********975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1549 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       561  (0.0312901); expected 358.6 (0.02)
Passed bias filter:                      511  (0.0285013); expected 358.6 (0.02)
Passed Vit filter:                        93  (0.00518713); expected 17.9 (0.001)
Passed Fwd filter:                        31  (0.00172904); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              29  [number of targets reported over threshold]
# CPU time: 1.01u 0.32s 00:00:01.33 Elapsed: 00:00:00.54
# Mc/sec: 8640.97
//
Query:       EEA18490.1  [L=1703]
Description: reverse transcriptase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.5e-36  124.8   0.0      7e-36  123.8   0.0    1.5  1  RVT_1            Reverse transcriptase (RNA-dependent DNA pol
    6.5e-25   87.3   0.0    2.2e-24   85.6   0.0    2.0  1  Exo_endo_phos_2  Endonuclease-reverse transcriptase
    0.00024   21.0   2.6    0.00024   21.0   2.6    2.6  2  zf-CCHC          Zinc knuckle
  ------ inclusion threshold ------
      0.051   12.5   4.8      0.097   11.5   4.1    1.8  2  Spc7             Spc7 kinetochore protein
       0.12   12.7   4.5        2.2    8.6   1.0    3.0  2  DBINO            DNA-binding domain
       0.24   12.2   0.1       0.24   12.2   0.1    3.0  3  zf-RVT           zinc-binding in reverse transcriptase


Domain annotation for each model (and alignments):
>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.8   0.0   2.4e-39     7e-36       5     221 ..     962    1212 ..     958    1213 .. 0.94

  Alignments for each domain:
  == domain 1  score: 123.8 bits;  conditional E-value: 2.4e-39
                  T.......S-EEE......-THHHHCTB--...........-------HHHH................HCCHTS--EEEEEEBCCGCCCSBB-GGGG CS
       RVT_1    5 g......pgsyRpisllsvdykalnkliakrLkdvl..ekllsenqpgfrpgrstldav...edllkalkkkkkaklllklDlkkaFdsvpleellr 90  
                  +      ++ +Rpisll +++k+l++++a+r++ ++    ll+++ +g r++rs ++a+   ++   ++++ ++   l+++D+k+a++ v  e+l++
  EEA18490.1  962 NkedytiAKAWRPISLLATLGKVLESVVAERISHAVetYGLLPTSHFGARKQRSAEQALlllQEQIYTAWRGRRVLSLISFDVKGAYNGVCKERLIQ 1058
                  455699999***************************8889**********************7777888**************************** PP

                  GGG-EEET..........................TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T......TEEECTTEEEEEESSHHH......H CS
       RVT_1   91 kltafkvptklinliksflstrsfsvrvnge.eskgryekkglpqGsvlSPllfnlfmnellrelrkrakgvtllrYaDDililskskee......l 180 
                  +++a ++p++l+++i++f s+r++++ +nge +  ++  ++glpqGs+lSP+lf +f  +l ++      +   ++++DD+   ++++++      +
  EEA18490.1 1059 RMKARGIPERLLRWIEAFCSERTATILINGEaSEVRSLPQAGLPQGSPLSPILFLFFNADLVQRQIDS--QGGAIAFVDDFNAWVTGPTAqgnrqgI 1153
                  *******************************88888899**********************9999995..89***************9999****** PP

                  HHHHHHHHHHHHHTT--BEGGG-EEE.......................ESSEEETTEE CS
       RVT_1  181 qelleaveewlkesglkinpeKtklvlft.................v.kseevkyLGvt 221 
                  +++++++ +w ++sg ++++eKt +++ft                 v  ++ vk+LGv+
  EEA18490.1 1154 ETIINETLDWERRSGATFEAEKTAIIHFTpkaykldrehftikrqtVePRDHVKILGVI 1212
                  ****************************************999976479999****996 PP

>> Exo_endo_phos_2  Endonuclease-reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.6   0.0   7.4e-28   2.2e-24       2     118 ..     556     686 ..     555     687 .. 0.92

  Alignments for each domain:
  == domain 1  score: 85.6 bits;  conditional E-value: 7.4e-28
  Exo_endo_phos_2   2 liisvYippsd......elenlestlekllselksp.kiiilGDfNakhplWgsedtds....sargeeLiefleehslsllnllksg.ptfks 83 
                       ++svY++  d      ++++l ++++k+ +++++  +i i+GDfN++++lWg+  +d+    + +++ +i+f++e++l+  +llk+g +t++ 
       EEA18490.1 556 FMASVYVEGGDaqalrdTCNHLREAITKVRRSTGTVvEITIVGDFNRHDQLWGG--DDVslerQGEADPIIDFMNEFALT--SLLKRGtKTWQG 645
                      689**********99999999999999999999999******************..55567999****************..****99677766 PP

  Exo_endo_phos_2  84 sng....sstiDltltsdnlals..kleleeedlgSDHrpi 118
                      +++    +stiDl+l+s+nl++s  k+ ++ +++gSDHr+i
       EEA18490.1 646 RGQdgdyESTIDLVLASENLTDSmvKCAIHGTEHGSDHRAI 686
                      66699999*******************************98 PP

>> zf-CCHC  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0   2.6   8.1e-08   0.00024       2      18 .]     404     420 ..     403     420 .. 0.94
   2 ?    1.9   5.0     0.088   2.6e+02       1      16 [.     422     437 ..     422     439 .. 0.86

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 8.1e-08
                 CTSSSSSSSSTTTTSTS CS
     zf-CCHC   2 kCynCGepGHiardCpk 18 
                 +CynC+e+GH a +C++
  EEA18490.1 404 QCYNCQEVGHKAFQCKN 420
                 6**************85 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.088
                 SCTSSSSSSSSTTTTS CS
     zf-CCHC   1 rkCynCGepGHiardC 16 
                 +kC +C  +GH  + C
  EEA18490.1 422 QKCAKCAAEGHHHSSC 437
                 59*********98888 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   4.1   3.2e-05     0.097     152     223 ..      84     155 ..      75     187 .. 0.85
   2 ?   -3.4   0.0       1.1   3.3e+03     271     297 ..     251     282 ..     241     288 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 3.2e-05
        Spc7 152 eedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkela 223
                 e+++  ++k  e + el++e++ + +  +eel++l+e+ ++ +++ +eeLe l++e+++  ae+++  + l+
  EEA18490.1  84 ENEDLGIAKLIEVIVELKQEIRVRDDLHKEELTELREEIRQRDDLHREELEGLKKEFSATLAEVRQELQTLT 155
                 6777889999***************************************************99996665555 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 1.1
        Spc7 271 lkeevkaleeltgwkivsls.....gstlelt 297
                 +++ev+++e+ t+w+   ++     ++ ++++
  EEA18490.1 251 VEKEVRTMEHRTNWRCRAVTvdpknSNRIKIA 282
                 6789999*******998877666544445555 PP

>> DBINO  DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.1     0.023        70      62      98 ..      32      68 ..      18      76 .. 0.84
   2 ?    8.6   1.0   0.00073       2.2      68     112 ..     769     813 ..     729     821 .. 0.88

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.023
       DBINO 62 lrakrlvremllfwkknekeereerkkaekealekak 98
                 r kr+++   ++ + +eke + ++k++++++ ++ +
  EEA18490.1 32 PRPKRATKPPNNYAREQEKEIELRNKRSQQKRTNQDR 68
                5789999999999999999999999999888888876 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.00073
       DBINO  68 vremllfwkknekeereerkkaekealekakkeeeereakRqqrk 112
                  r + ++w+ + ++er + +k    +  +  + ++ ++a Rqq+k
  EEA18490.1 769 LRHIYTYWRNHARSERRAGRKVANLEETADNAAKQYHDAIRQQKK 813
                 6899**************999999999999999**********98 PP

>> zf-RVT  zinc-binding in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   1.4       5.9   1.8e+04      59      83 ..     403     423 ..     399     424 .. 0.79
   2 ?   -3.0   0.2       4.4   1.3e+04       9      38 ..     747     777 ..     743     785 .. 0.78
   3 ?   12.2   0.1   7.9e-05      0.24      52      80 ..    1619    1646 ..    1605    1649 .. 0.81

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 5.9
      zf-RVT  59 srCqlCgqeeEtieHlfleCpfake 83 
                 ++C+ C++    + H  ++C+ +++
  EEA18490.1 403 AQCYNCQE----VGHKAFQCKNSQK 423
                 67999988....7999999988775 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 4.4
      zf-RVT   9 llrekkekvklakliWkska.ppkvkfflWl 38 
                  l+ k + +++ak  W++ + ++++ +  W+
  EEA18490.1 747 TLTPKAKPSPYAKRWWTTDLtQLRHIYTYWR 777
                 5677778889999999998877888888886 PP

  == domain 3  score: 12.2 bits;  conditional E-value: 7.9e-05
      zf-RVT   52 krgiesssrCqlCgqeeEtieHlfleCpf 80  
                  + ++++ ++C+ Cgq+ Et+eH +++C++
  EEA18490.1 1619 RINVAQTDQCP-CGQARETVEHFLFRCQK 1646
                  55667677775.8999***********75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1703 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1272  (0.0709465); expected 358.6 (0.02)
Passed bias filter:                      634  (0.0353617); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.08u 0.34s 00:00:01.42 Elapsed: 00:00:00.52
# Mc/sec: 9873.66
//
Query:       EEA18491.1  [L=134]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (134 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       205  (0.011434); expected 358.6 (0.02)
Passed bias filter:                      190  (0.0105974); expected 358.6 (0.02)
Passed Vit filter:                        10  (0.000557756); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.36u 0.28s 00:00:00.64 Elapsed: 00:00:00.42
# Mc/sec: 963.01
//
Query:       EEA18492.1  [L=1597]
Description: WD-repeat protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   3.5e-139  448.5  39.5    1.3e-10   41.7   0.0   14.8 14  WD40             WD domain, G-beta repeat
    1.2e-48  163.3   4.1    0.00079   19.7   0.0   12.9 12  ANAPC4_WD40      Anaphase-promoting complex subunit 4 WD40 do
    4.8e-20   72.3   0.0    1.2e-06   28.5   0.0    5.3  6  eIF2A            Eukaryotic translation initiation factor eIF
      9e-18   64.3   8.8       0.92    8.4   0.0   11.8 12  Ge1_WD40         WD40 region of Ge1, enhancer of mRNA-decappi
    3.5e-14   52.8   0.0     0.0057   16.0   0.0    6.8  7  WD40_like        WD40-like domain
    1.9e-13   49.8   0.0        7.5    6.3   0.0   10.0  8  Proteasome_A_N   Proteasome subunit A N-terminal signature
    3.7e-12   45.8   1.1         13    5.9   0.0   10.4 10  PD40             WD40-like Beta Propeller Repeat
    1.4e-09   38.1   0.0    3.2e-09   36.9   0.0    1.6  1  NACHT            NACHT domain
    2.9e-09   36.5   0.2    1.2e-08   34.6   0.2    2.0  1  PNP_UDP_1        Phosphorylase superfamily
      3e-09   37.1   0.0        8.6    6.8   0.0    9.3 10  Ret2_MD          RNA editing 3' terminal uridylyl transferase
    1.2e-08   35.5   0.0    5.4e-08   33.4   0.0    2.1  1  AAA_16           AAA ATPase domain
    3.1e-08   33.0   0.2        9.3    5.1   0.0    7.2  8  DUF4784          Domain of unknown function (DUF4784)
    6.4e-07   27.8   2.4       0.14   10.1   0.4    4.9  4  IKI3             IKI3 family
    6.6e-07   28.2   0.2       0.16   10.5   0.0    4.7  6  Cytochrom_D1     Cytochrome D1 heme domain
    2.3e-06   27.8  12.2         12    6.3   0.0    9.1  9  DUF5122          Domain of unknown function (DUF5122) beta-pr
    4.9e-05   22.9   0.1        0.3   10.5   0.0    4.1  5  DUF5046          Domain of unknown function (DUF5046)
    0.00014   21.0   3.9        6.3    5.8   0.0    5.4  6  DUF1513          Protein of unknown function (DUF1513)
      0.003   18.0   0.0       0.01   16.2   0.0    1.9  1  AAA              ATPase family associated with various cellul
     0.0046   17.0   0.0         27    5.4   0.0    6.3  5  MORN_2           MORN repeat variant
  ------ inclusion threshold ------
      0.021   15.4   0.0         92    3.7   0.0    5.1  4  Stimulus_sens_1  Stimulus-sensing domain
      0.041   13.1   0.1        2.9    7.1   0.0    3.3  4  Lactonase        Lactonase, 7-bladed beta-propeller
      0.049   13.4   0.0      0.096   12.4   0.0    1.4  1  AAA_30           AAA domain
      0.056   14.0   0.0       0.17   12.4   0.0    1.9  1  AAA_18           AAA domain
      0.056   13.3   0.1       0.11   12.4   0.1    1.4  1  APS_kinase       Adenylylsulphate kinase
      0.081   12.1   0.0       0.16   11.2   0.0    1.4  1  NB-ARC           NB-ARC domain
       0.14   11.3   0.0       0.25   10.5   0.0    1.3  1  PIF1             PIF1-like helicase


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.7   0.0   1.9e-13   1.3e-10       3      38 .]     951     987 ..     949     987 .. 0.95
   2 !   37.8   0.0   3.1e-12   2.1e-09       2      38 .]     992    1029 ..     991    1029 .. 0.93
   3 !   39.4   0.1     1e-12   6.9e-10       1      38 []    1033    1071 ..    1033    1071 .. 0.94
   4 !   32.8   0.0   1.2e-10   7.9e-08       1      38 []    1075    1113 ..    1075    1113 .. 0.94
   5 !   28.1   0.1   3.7e-09   2.5e-06       2      38 .]    1118    1155 ..    1117    1155 .. 0.91
   6 !   35.2   0.2   2.1e-11   1.5e-08       1      38 []    1159    1197 ..    1159    1197 .. 0.94
   7 !   30.3   0.0   7.5e-10   5.2e-07       2      38 .]    1202    1239 ..    1201    1239 .. 0.88
   8 !   37.1   0.0   5.3e-12   3.7e-09       4      38 .]    1246    1281 ..    1244    1281 .. 0.94
   9 !   32.2   0.0   1.9e-10   1.3e-07       1      38 []    1285    1324 ..    1285    1324 .. 0.89
  10 !   37.7   0.3   3.4e-12   2.3e-09       1      38 []    1328    1366 ..    1328    1366 .. 0.94
  11 !   40.3   0.0   5.1e-13   3.5e-10       1      38 []    1370    1408 ..    1370    1408 .. 0.93
  12 !   32.1   0.2     2e-10   1.4e-07       2      38 .]    1413    1450 ..    1412    1450 .. 0.94
  13 !   30.0   0.2   9.1e-10   6.3e-07       1      38 []    1454    1492 ..    1454    1492 .. 0.92
  14 !   11.6   0.0    0.0006      0.41       1      27 [.    1496    1523 ..    1496    1528 .. 0.89

  Alignments for each domain:
  == domain 1  score: 41.7 bits;  conditional E-value: 1.9e-13
                 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +l+t++GH ++v ++afspdg+++asGsdD+tv++W+
  EEA18492.1 951 LLQTIEGHsKPVKAVAFSPDGKLVASGSDDKTVKLWN 987
                 68999***999*************************8 PP

  == domain 2  score: 37.8 bits;  conditional E-value: 3.1e-12
                  EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38  
                  ++++t+++H  sv ++afspdg+++asGsdD++vr+W+
  EEA18492.1  992 SLQQTIEAHsESVKAVAFSPDGKLVASGSDDRNVRLWN 1029
                  68999****777*************************8 PP

  == domain 3  score: 39.4 bits;  conditional E-value: 1e-12
                  TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38  
                  g++l+tl+GH +sv+++ fspdg+++asGs D+tv++Wd
  EEA18492.1 1033 GSLLQTLKGHsQSVHAVMFSPDGKLIASGSGDKTVKLWD 1071
                  5789******888****************99*******9 PP

  == domain 4  score: 32.8 bits;  conditional E-value: 1.2e-10
                  TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38  
                  g++++t++GHs  v+++afs dg+++asGs D t ++Wd
  EEA18492.1 1075 GSLQQTFKGHSElVNAVAFSLDGKLVASGSNDTTFKLWD 1113
                  57899*****668*************************9 PP

  == domain 5  score: 28.1 bits;  conditional E-value: 3.7e-09
                  EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38  
                  ++++t+ +Hs  +  +afspd +++asGsdD+ +++Wd
  EEA18492.1 1118 SLQQTYVTHSKmILIVAFSPDCKLVASGSDDKIIKLWD 1155
                  7899*****44799***********************9 PP

  == domain 6  score: 35.2 bits;  conditional E-value: 2.1e-11
                  TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38  
                  g++lrtl+GHs+ ++++afs dg+++asGs D+tv++Wd
  EEA18492.1 1159 GNLLRTLEGHSHwISAIAFSLDGKLMASGSGDKTVKLWD 1197
                  689*******667****************99*******9 PP

  == domain 7  score: 30.3 bits;  conditional E-value: 7.5e-10
                  EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38  
                  ++++tl+   +sv+++afspdg++++sG +D+tv++Wd
  EEA18492.1 1202 SLQQTLESYsDSVNAVAFSPDGKLVVSGLEDNTVKLWD 1239
                  577888888566****************99*******9 PP

  == domain 8  score: 37.1 bits;  conditional E-value: 5.3e-12
                  EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38  
                  +++l+GH +sv+++afspdg+++asGs D  +++Wd
  EEA18492.1 1246 QQSLEGHsDSVNAVAFSPDGKLVASGSFDTAIKLWD 1281
                  789****777*************************9 PP

  == domain 9  score: 32.2 bits;  conditional E-value: 1.9e-10
                  TEEEEEEESSSS.EEEEEEETTSSEEE.EEETTSEEEEEE CS
        WD40    1 gqclrtltGHss.vtslafspdgawla.sGsdDgtvriWd 38  
                  g++l+tl+GHs  +  lafspdg++++ s+s+D+ v++Wd
  EEA18492.1 1285 GSLLQTLKGHSQmIDTLAFSPDGRFVVvSSSEDRIVKLWD 1324
                  5789******668************864889********9 PP

  == domain 10  score: 37.7 bits;  conditional E-value: 3.4e-12
                  TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38  
                  g+++++l+GHs+ v+++ fspdg+++asGs D t+++W+
  EEA18492.1 1328 GNLQQSLKGHSHwVRAVVFSPDGKLVASGSFDTTIKLWN 1366
                  6889******667*************************8 PP

  == domain 11  score: 40.3 bits;  conditional E-value: 5.1e-13
                  TEEEEEEESSSS..EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    1 gqclrtltGHss..vtslafspdgawlasGsdDgtvriWd 38  
                  g++l+tl+GH s  v+ +afsp+g+++asGs D+tvr+Wd
  EEA18492.1 1370 GSLLQTLKGH-SllVNTVAFSPNGKLIASGSSDKTVRLWD 1408
                  5789******.6699***************99*******9 PP

  == domain 12  score: 32.1 bits;  conditional E-value: 2e-10
                  EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38  
                  +++++++ H  sv+ +afs+d++++asGs D+tv++Wd
  EEA18492.1 1413 SLQQIFKSHsESVNIVAFSSDSKLVASGSVDKTVKLWD 1450
                  7899*****777*************************9 PP

  == domain 13  score: 30.0 bits;  conditional E-value: 9.1e-10
                  TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38  
                  g++l+tl+GH ++v+++ fs d +++asGs D+t ++Wd
  EEA18492.1 1454 GSLLQTLEGHsDWVNAVTFSLDTRLVASGSSDKTAKLWD 1492
                  57899*****666****************99*******9 PP

  == domain 14  score: 11.6 bits;  conditional E-value: 0.0006
                  TEEEEEEESS.SSEEEEEEETTSSEEEE CS
        WD40    1 gqclrtltGH.ssvtslafspdgawlas 27  
                  g++++tl+GH +s+++l+fs dg++l++
  EEA18492.1 1496 GNLQQTLDGHsDSIYALSFSLDGKLLFT 1523
                  6899******777***********9975 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   0.0   7.4e-06    0.0051      31      82 ..     949    1003 ..     937    1005 .. 0.86
   2 !   19.7   0.0   1.2e-06   0.00079      35      86 ..     998    1048 ..     994    1051 .. 0.89
   3 !   14.2   0.0     6e-05     0.042      36      80 ..    1041    1085 ..    1038    1087 .. 0.90
   4 !   12.8   0.0   0.00016      0.11      36      87 ..    1083    1133 ..    1078    1136 .. 0.87
   5 !   16.5   0.0   1.2e-05     0.008       2      81 ..    1134    1212 ..    1133    1215 .. 0.89
   6 !   13.9   0.0   7.4e-05     0.051      38      77 ..    1211    1250 ..    1205    1255 .. 0.84
   7 !   14.8   0.0   3.8e-05     0.026      35      81 ..    1250    1296 ..    1241    1299 .. 0.88
   8 !   11.6   0.0   0.00039      0.27      37      80 ..    1294    1338 ..    1290    1341 .. 0.84
   9 !   12.1   0.0   0.00027      0.19      38      79 ..    1338    1379 ..    1334    1383 .. 0.89
  10 !   19.2   0.0   1.6e-06    0.0011      38      89 ..    1380    1430 ..    1377    1432 .. 0.90
  11 !   12.7   0.1   0.00017      0.12      29      89 ..    1417    1472 ..    1413    1473 .. 0.86
  12 ?    5.6   0.0     0.028        20      40      89 ..    1466    1514 ..    1461    1517 .. 0.89

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 7.4e-06
  ANAPC4_WD40   31 tl...eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksek 82  
                   ++   + +++++ v+++a++pdgkl a + +d +v+l +  +g + ++++++se+
   EEA18492.1  949 SAllqTIEGHSKPVKAVAFSPDGKLVASGSDDKTVKLWNPATGSLQQTIEAHSES 1003
                   444444678999*************************************999884 PP

  == domain 2  score: 19.7 bits;  conditional E-value: 1.2e-06
  ANAPC4_WD40   35 dkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtc 86  
                   ++++++v+++a++pdgkl a + +d +vrl + e+g ++++l+ +s++ v  
   EEA18492.1  998 EAHSESVKAVAFSPDGKLVASGSDDRNVRLWNPETGSLLQTLKGHSQS-VHA 1048
                   567899************************************999985.554 PP

  == domain 3  score: 14.2 bits;  conditional E-value: 6e-05
  ANAPC4_WD40   36 kedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvks 80  
                   +++++v++++++pdgkl+a +  d +v+l d  +g + ++++ +s
   EEA18492.1 1041 GHSQSVHAVMFSPDGKLIASGSGDKTVKLWDPATGSLQQTFKGHS 1085
                   57889******************************9999988766 PP

  == domain 4  score: 12.8 bits;  conditional E-value: 0.00016
  ANAPC4_WD40   36 kedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtcl 87  
                   ++++ v+++a++ dgkl a + +d++ +l d  +g + +++ ++s+  +  +
   EEA18492.1 1083 GHSELVNAVAFSLDGKLVASGSNDTTFKLWDLATGSLQQTYVTHSK-MILIV 1133
                   57789********************************999998888.46655 PP

  == domain 5  score: 16.5 bits;  conditional E-value: 1.2e-05
  ANAPC4_WD40    2 swcptmDLiAlatedgellvfRlngqrvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvkse 81  
                   +++p   L+A +++d+ + +  l   ++  +  +++++ ++++a++ dgkl+a +  d +v+l d  +g + ++l+  s+
   EEA18492.1 1134 AFSPDCKLVASGSDDKIIKLWDLGTGNLLRT-LEGHSHWISAIAFSLDGKLMASGSGDKTVKLWDPATGSLQQTLESYSD 1212
                   7899999999999999999999977777776.589999*******************************99999988876 PP

  == domain 6  score: 13.9 bits;  conditional E-value: 7.4e-05
  ANAPC4_WD40   38 dsevrsLaWkpdgklLavaysdgevrlldaesgkvvhsls 77  
                   + +v+++a++pdgkl + + +d++v+l d+ +  + +sl+
   EEA18492.1 1211 SDSVNAVAFSPDGKLVVSGLEDNTVKLWDSATSILQQSLE 1250
                   5689*************************99876666665 PP

  == domain 7  score: 14.8 bits;  conditional E-value: 3.8e-05
  ANAPC4_WD40   35 dkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvkse 81  
                   ++++ +v+++a++pdgkl a +  d++++l d  +g ++++l+ +s+
   EEA18492.1 1250 EGHSDSVNAVAFSPDGKLVASGSFDTAIKLWDPATGSLLQTLKGHSQ 1296
                   677889**********************************9988775 PP

  == domain 8  score: 11.6 bits;  conditional E-value: 0.00039
  ANAPC4_WD40   37 edsevrsLaWkpdgklLavaysdg.evrlldaesgkvvhslsvks 80  
                   +++ +  La++pdg++ +v+ s+   v+l d+ +g++ +sl+ +s
   EEA18492.1 1294 HSQMIDTLAFSPDGRFVVVSSSEDrIVKLWDSATGNLQQSLKGHS 1338
                   678899************9987663899********999988766 PP

  == domain 9  score: 12.1 bits;  conditional E-value: 0.00027
  ANAPC4_WD40   38 dsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvk 79  
                   ++ vr++ ++pdgkl a +  d++++l +  +g ++++l+ +
   EEA18492.1 1338 SHWVRAVVFSPDGKLVASGSFDTTIKLWNLATGSLLQTLKGH 1379
                   56799*******************************998766 PP

  == domain 10  score: 19.2 bits;  conditional E-value: 1.6e-06
  ANAPC4_WD40   38 dsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89  
                   +  v+ +a++p+gkl+a + sd +vrl d  +g + + ++ +se+ v+ + +
   EEA18492.1 1380 SLLVNTVAFSPNGKLIASGSSDKTVRLWDLATGSLQQIFKSHSES-VNIVAF 1430
                   56799***********************************99995.888776 PP

  == domain 11  score: 12.7 bits;  conditional E-value: 0.00017
  ANAPC4_WD40   29 vwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89  
                   +++     ++++v+ +a++ d kl a +  d +v+l d+ +g ++++l+ +s+  v+ +++
   EEA18492.1 1417 IFKS----HSESVNIVAFSSDSKLVASGSVDKTVKLWDSTTGSLLQTLEGHSD-WVNAVTF 1472
                   5554....7899************************************99998.4776665 PP

  == domain 12  score: 5.6 bits;  conditional E-value: 0.028
  ANAPC4_WD40   40 evrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89  
                    v+++ ++ d +l a + sd + +l d  +g++ ++l+ +s++ +  l++
   EEA18492.1 1466 WVNAVTFSLDTRLVASGSSDKTAKLWDPATGNLQQTLDGHSDS-IYALSF 1514
                   68999*********************************99995.888877 PP

>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.5   0.0   0.00057       0.4      60     158 ..     960    1058 ..     949    1059 .. 0.76
   2 !   10.1   0.0   0.00077      0.53      61     159 ..    1045    1143 ..    1034    1166 .. 0.83
   3 !    6.7   0.0    0.0087         6      77     118 ..    1185    1229 ..    1164    1240 .. 0.78
   4 !   28.5   0.0   1.8e-09   1.2e-06      61     176 ..    1213    1323 ..    1199    1337 .. 0.80
   5 !   18.3   0.0   2.4e-06    0.0017      63     184 ..    1342    1458 ..    1334    1462 .. 0.81
   6 !   12.4   0.0   0.00015       0.1      63     142 ..    1384    1461 ..    1380    1490 .. 0.66

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00057
                  S.EEEEEE-TTSS-EEEEESSSSCEEEEEECS...CEEEEEEEEES--EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE.-TT--E.EEE CS
       eIF2A   60 gpihdvaWspkskefaviyGkmpakvslfdlk...vkviskleeqkrNtiffspkgklvllaGfgnlaGeleiwdvkkkkkiakae.aanatl.vew 151 
                   p+++va sp++k  +v  G  +++v+l++     ++++ + ++++  ++ fsp gklv+ +   +   ++ +w+ ++ + +++++ ++++++ v +
  EEA18492.1  960 KPVKAVAFSPDGK--LVASGSDDKTVKLWNPAtgsLQQTIEAHSESVKAVAFSPDGKLVASGS-DDR--NVRLWNPETGSLLQTLKgHSQSVHaVMF 1051
                  4899999999998..7889999*******9955457777888888899999******998764.333..6889999988888887634444433778 PP

                  -TTSSEE CS
       eIF2A  152 spdgryv 158 
                  spdg+++
  EEA18492.1 1052 SPDGKLI 1058
                  9998876 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00077
                  .EEEEEE-TTSS-EEEEESSSSCEEEEEECS...CEEEEEEEEES--EEEE-TTSSEEEEE-TTSSS-EEEEEETT..TTEEEEEEE-TT--EEEE- CS
       eIF2A   61 pihdvaWspkskefaviyGkmpakvslfdlk...vkviskleeqkrNtiffspkgklvllaGfgnlaGeleiwdvk..kkkkiakaeaanatlvews 152 
                   +h+v  sp++k  ++  G  +++v+l+d     +++++k +++  N++ fs  gklv+ +       + ++wd    ++++   +++++   v +s
  EEA18492.1 1045 SVHAVMFSPDGK--LIASGSGDKTVKLWDPAtgsLQQTFKGHSELVNAVAFSLDGKLVASGSNDT---TFKLWDLAtgSLQQTYVTHSKMILIVAFS 1136
                  599999***999..6779***********96555778888888999***********99765444...59999998667778888888899999999 PP

                  TTSSEEE CS
       eIF2A  153 pdgryvl 159 
                  pd ++v+
  EEA18492.1 1137 PDCKLVA 1143
                  9998876 PP

  == domain 3  score: 6.7 bits;  conditional E-value: 0.0087
                  EESSSSCEEEEEECS...CEEEEEEEEES--EEEE-TTSSEEEEE CS
       eIF2A   77 iyGkmpakvslfdlk...vkviskleeqkrNtiffspkgklvlla 118 
                    G  +++v+l+d     ++++ +  +++ N++ fsp gklv+ +
  EEA18492.1 1185 ASGSGDKTVKLWDPAtgsLQQTLESYSDSVNAVAFSPDGKLVVSG 1229
                  47889999*****9555578888888999************9864 PP

  == domain 4  score: 28.5 bits;  conditional E-value: 1.8e-09
                  .EEEEEE-TTSS-EEEEESSSSCEEEEEECS...CEEEEEEEEES--EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE..-TT--EEEE- CS
       eIF2A   61 pihdvaWspkskefaviyGkmpakvslfdlk...vkviskleeqkrNtiffspkgklvllaGfgnlaGeleiwdvkkkkkiakae..aanatlvews 152 
                   + +va sp++k  +v+ G  +++v+l+d+    +++  + ++++ N++ fsp gklv+ + f      +++wd  + + +++++  +++  ++ +s
  EEA18492.1 1213 SVNAVAFSPDGK--LVVSGLEDNTVKLWDSAtsiLQQSLEGHSDSVNAVAFSPDGKLVASGSFDTA---IKLWDPATGSLLQTLKghSQMIDTLAFS 1304
                  588999999998..89**************8445566666778899**************999876...*******877777765326778899*** PP

                  TTSSEEEEEE-TTT-SSS-EEEEE CS
       eIF2A  153 pdgryvlTattaprlrvdngfkiw 176 
                  pdgr+v+ +++      d  +k+w
  EEA18492.1 1305 PDGRFVVVSSSE-----DRIVKLW 1323
                  *******99988.....4445555 PP

  == domain 5  score: 18.3 bits;  conditional E-value: 2.4e-06
                  EEEEE-TTSS-EEEEESSSSCEEEEEECS.CEEEEEEEEES..--EEEE-TTSSEEEEE-TTSSS-EEEEEETT..TTEEEEEEE-TT--EEEE-TT CS
       eIF2A   63 hdvaWspkskefaviyGkmpakvslfdlk.vkviskleeqk..rNtiffspkgklvllaGfgnlaGeleiwdvk..kkkkiakaeaanatlvewspd 154 
                   +v  sp++k  +v  G  + +++l++l  ++++ +l+ ++   Nt+ fsp+gkl++ +    +   + +wd    ++++i k +++    v +s d
  EEA18492.1 1342 RAVVFSPDGK--LVASGSFDTTIKLWNLAtGSLLQTLKGHSllVNTVAFSPNGKLIASGSSDKT---VRLWDLAtgSLQQIFKSHSESVNIVAFSSD 1433
                  5666666666..6889***********96477777777665337************99888777...*****998899******************* PP

                  SSEEEEEE-TTT-SSS-EEEEE.ETTTEEEE CS
       eIF2A  155 gryvlTattaprlrvdngfkiw.sysGklvy 184 
                  +++v+         vd ++k+w s +G+l++
  EEA18492.1 1434 SKLVASG------SVDKTVKLWdSTTGSLLQ 1458
                  **98643......378888888445687776 PP

  == domain 6  score: 12.4 bits;  conditional E-value: 0.00015
                  EEEEE-TTSS-EEEEESSSSCEEEEEECS...CEEEEEEEEES--EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE CS
       eIF2A   63 hdvaWspkskefaviyGkmpakvslfdlk...vkviskleeqkrNtiffspkgklvllaGfgnlaGeleiwdvkkkkkiakae 142 
                    va sp++k  ++  G ++++v l+dl    +++i+k ++++ N + fs+  klv+ +    +   +++wd ++ + ++++e
  EEA18492.1 1384 NTVAFSPNGK--LIASGSSDKTVRLWDLAtgsLQQIFKSHSESVNIVAFSSDSKLVASGSVDKT---VKLWDSTTGSLLQTLE 1461
                  4556666666..4567777777777777444477777777777777777777777777766665...7777777666555554 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.4   0.0    0.0013      0.92     181     214 ..     952     986 ..     930     990 .. 0.82
   2 !    7.4   0.0    0.0026       1.8     183     214 ..     996    1028 ..     987    1032 .. 0.87
   3 !    5.7   0.0     0.009       6.2     184     214 ..    1039    1070 ..    1029    1074 .. 0.85
   4 ?    4.4   0.0     0.022        15     184     217 ..    1081    1115 ..    1073    1127 .. 0.81
   5 ?    2.7   0.0      0.07        48     185     215 ..    1125    1155 ..    1115    1161 .. 0.84
   6 ?    2.1   0.0      0.11        75     184     214 ..    1165    1196 ..    1157    1200 .. 0.87
   7 ?    1.2   0.0      0.21   1.5e+02     188     215 ..    1211    1239 ..    1197    1247 .. 0.83
   8 !    5.9   0.1    0.0075       5.2     184     214 ..    1249    1280 ..    1239    1284 .. 0.86
   9 ?    3.7   0.0     0.037        26     184     215 ..    1291    1324 ..    1282    1333 .. 0.76
  10 !    5.9   0.0    0.0079       5.4     184     216 ..    1334    1367 ..    1324    1374 .. 0.83
  11 !    6.0   0.0     0.007       4.8     184     216 ..    1376    1409 ..    1366    1417 .. 0.84
  12 ?    1.5   0.1      0.17   1.1e+02     184     215 ..    1418    1450 ..    1408    1455 .. 0.85

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0013
    Ge1_WD40 181 llkieehs.liveaafspdGtalatasedGevkff 214
                 l  ie hs  +   afspdG  +a  s d +vk++
  EEA18492.1 952 LQTIEGHSkPVKAVAFSPDGKLVASGSDDKTVKLW 986
                 446899994577779******************99 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0026
    Ge1_WD40  183 kieehs.liveaafspdGtalatasedGevkff 214 
                   ie hs  +   afspdG  +a  s d  v+++
  EEA18492.1  996 TIEAHSeSVKAVAFSPDGKLVASGSDDRNVRLW 1028
                  5888985688889******************98 PP

  == domain 3  score: 5.7 bits;  conditional E-value: 0.009
    Ge1_WD40  184 ieehs.liveaafspdGtalatasedGevkff 214 
                  ++ hs  +   +fspdG  +a  s d +vk++
  EEA18492.1 1039 LKGHSqSVHAVMFSPDGKLIASGSGDKTVKLW 1070
                  677885677789******************98 PP

  == domain 4  score: 4.4 bits;  conditional E-value: 0.022
    Ge1_WD40  184 ieehslivea.afspdGtalatasedGevkffqvy 217 
                  ++ hs++v+a afs dG  +a  s+d + k++ + 
  EEA18492.1 1081 FKGHSELVNAvAFSLDGKLVASGSNDTTFKLWDLA 1115
                  678997666548******************99875 PP

  == domain 5  score: 2.7 bits;  conditional E-value: 0.07
    Ge1_WD40  185 eehsliveaafspdGtalatasedGevkffq 215 
                  ++  +i   afspd   +a  s d ++k++ 
  EEA18492.1 1125 THSKMILIVAFSPDCKLVASGSDDKIIKLWD 1155
                  344588999*******************997 PP

  == domain 6  score: 2.1 bits;  conditional E-value: 0.11
    Ge1_WD40  184 ieehs.liveaafspdGtalatasedGevkff 214 
                  +e hs  i+  afs dG  +a  s d +vk++
  EEA18492.1 1165 LEGHShWISAIAFSLDGKLMASGSGDKTVKLW 1196
                  567875788899******************98 PP

  == domain 7  score: 1.2 bits;  conditional E-value: 0.21
    Ge1_WD40  188 s.liveaafspdGtalatasedGevkffq 215 
                  s  +   afspdG  +    ed +vk++ 
  EEA18492.1 1211 SdSVNAVAFSPDGKLVVSGLEDNTVKLWD 1239
                  43577889******************996 PP

  == domain 8  score: 5.9 bits;  conditional E-value: 0.0075
    Ge1_WD40  184 ieehs.liveaafspdGtalatasedGevkff 214 
                  +e hs  +   afspdG  +a  s d  +k++
  EEA18492.1 1249 LEGHSdSVNAVAFSPDGKLVASGSFDTAIKLW 1280
                  567776788889******************98 PP

  == domain 9  score: 3.7 bits;  conditional E-value: 0.037
    Ge1_WD40  184 ieehs.liveaafspdGtalat.asedGevkffq 215 
                  ++ hs +i + afspdG  + + +sed +vk++ 
  EEA18492.1 1291 LKGHSqMIDTLAFSPDGRFVVVsSSEDRIVKLWD 1324
                  677884666779*****97766157899999996 PP

  == domain 10  score: 5.9 bits;  conditional E-value: 0.0079
    Ge1_WD40  184 ieehs.liveaafspdGtalatasedGevkffqv 216 
                  ++ hs  +   +fspdG  +a  s d ++k++ +
  EEA18492.1 1334 LKGHShWVRAVVFSPDGKLVASGSFDTTIKLWNL 1367
                  567874566678*******************976 PP

  == domain 11  score: 6.0 bits;  conditional E-value: 0.007
    Ge1_WD40  184 ieehs.liveaafspdGtalatasedGevkffqv 216 
                  ++ hs l+ + afsp+G  +a  s+d +v+++ +
  EEA18492.1 1376 LKGHSlLVNTVAFSPNGKLIASGSSDKTVRLWDL 1409
                  678995566789*******************986 PP

  == domain 12  score: 1.5 bits;  conditional E-value: 0.17
    Ge1_WD40  184 ieehs.liveaafspdGtalatasedGevkffq 215 
                  +++hs  +   afs+d   +a  s d +vk++ 
  EEA18492.1 1418 FKSHSeSVNIVAFSSDSKLVASGSVDKTVKLWD 1450
                  46677578889*******************995 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.7   0.0    0.0058         4       3      56 ..     962    1015 ..     960    1027 .. 0.87
   2 ?    5.1   0.0     0.018        12       3      53 ..    1004    1054 ..    1002    1067 .. 0.84
   3 !    6.2   0.0    0.0084       5.8       3      73 ..    1046    1117 ..    1044    1129 .. 0.85
   4 !    6.8   0.0    0.0053       3.6       5      53 ..    1174    1222 ..    1171    1227 .. 0.88
   5 ?    5.4   0.0     0.014       9.6       5      56 ..    1216    1267 ..    1214    1281 .. 0.83
   6 !   16.0   0.0   8.2e-06    0.0057       5      62 ..    1385    1443 ..    1382    1459 .. 0.86
   7 ?    3.3   0.0     0.063        43       5      57 ..    1469    1521 ..    1465    1537 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0058
   WD40_like    3 iYsidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvklldddli 56  
                  + ++ +s++g+l++ G++d+++++ +  ++ + + +e  ++Sv  v +  d ++
  EEA18492.1  962 VKAVAFSPDGKLVASGSDDKTVKLWNPATGSLQQTIEAHSESVKAVAFSPDGKL 1015
                  67899**************************************98887666554 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.018
   WD40_like    3 iYsidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvklldd 53  
                  + ++ +s++g+l++ G++d ++++ + e++ + + +++ ++Sv  v +  d
  EEA18492.1 1004 VKAVAFSPDGKLVASGSDDRNVRLWNPETGSLLQTLKGHSQSVHAVMFSPD 1054
                  668999************************************977666444 PP

  == domain 3  score: 6.2 bits;  conditional E-value: 0.0084
   WD40_like    3 iYsidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvkl.ldddlilvvtlDGtillsllene 73  
                  + ++ +s++g+li+ G+ d+++++ +  ++ + + +++ ++ v  v + ld++l+  +++D t+ l +l  +
  EEA18492.1 1046 VHAVMFSPDGKLIASGSGDKTVKLWDPATGSLQQTFKGHSELVNAVAFsLDGKLVASGSNDTTFKLWDLATG 1117
                  788999***********************************9999998466667778899999988777665 PP

  == domain 4  score: 6.8 bits;  conditional E-value: 0.0053
   WD40_like    5 sidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvklldd 53  
                  +i +s +g+l++ G+ d+++++ +  ++ + + +es++dSv  v +  d
  EEA18492.1 1174 AIAFSLDGKLMASGSGDKTVKLWDPATGSLQQTLESYSDSVNAVAFSPD 1222
                  7899*************************************88877655 PP

  == domain 5  score: 5.4 bits;  conditional E-value: 0.014
   WD40_like    5 sidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvklldddli 56  
                  ++ +s++g+l++ G +d+++++ +  + ++ +++e+ +dSv  v +  d ++
  EEA18492.1 1216 AVAFSPDGKLVVSGLEDNTVKLWDSATSILQQSLEGHSDSVNAVAFSPDGKL 1267
                  7889*************************************99988766543 PP

  == domain 6  score: 16.0 bits;  conditional E-value: 8.2e-06
   WD40_like    5 sidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvklldddlilv.vtlD 62  
                  ++ +s++g+li+ G+ d+++++ +l ++ + +i++s ++Sv  v + +d +++  +++D
  EEA18492.1 1385 TVAFSPNGKLIASGSSDKTVRLWDLATGSLQQIFKSHSESVNIVAFSSDSKLVAsGSVD 1443
                  7899****************************************999888655314556 PP

  == domain 7  score: 3.3 bits;  conditional E-value: 0.063
   WD40_like    5 sidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvklldddlil 57  
                  ++ +s +  l++ G+ d+++++ +  ++++ + +++ +dS+    +  d ++l
  EEA18492.1 1469 AVTFSLDTRLVASGSSDKTAKLWDPATGNLQQTLDGHSDSIYALSFSLDGKLL 1521
                  7889999*********************************9877776665554 PP

>> Proteasome_A_N  Proteasome subunit A N-terminal signature
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0     0.047        32       8      14 ..     967     973 ..     964     974 .. 0.89
   2 ?    4.5   0.0     0.042        29       8      14 ..    1009    1015 ..    1005    1016 .. 0.87
   3 ?    5.9   0.0     0.015        11       6      14 ..    1049    1057 ..    1047    1058 .. 0.83
   4 ?    4.5   0.0      0.04        28       7      14 ..    1218    1225 ..    1215    1226 .. 0.86
   5 ?    4.5   0.0      0.04        28       7      14 ..    1260    1267 ..    1257    1268 .. 0.86
   6 ?    2.8   0.0      0.14        94       8      13 ..    1303    1308 ..    1299    1308 .. 0.90
   7 ?    6.3   0.0     0.011       7.5       7      14 ..    1345    1352 ..    1342    1353 .. 0.86
   8 ?    2.3   0.0       0.2   1.4e+02       7      14 ..    1387    1394 ..    1384    1395 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.047
  Proteasome_A_N   8 FSPdGRL 14 
                     FSPdG+L
      EEA18492.1 967 FSPDGKL 973
                     ******9 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.042
  Proteasome_A_N    8 FSPdGRL 14  
                      FSPdG+L
      EEA18492.1 1009 FSPDGKL 1015
                      ******9 PP

  == domain 3  score: 5.9 bits;  conditional E-value: 0.015
  Proteasome_A_N    6 ttFSPdGRL 14  
                       +FSPdG+L
      EEA18492.1 1049 VMFSPDGKL 1057
                      58******9 PP

  == domain 4  score: 4.5 bits;  conditional E-value: 0.04
  Proteasome_A_N    7 tFSPdGRL 14  
                       FSPdG+L
      EEA18492.1 1218 AFSPDGKL 1225
                      5******9 PP

  == domain 5  score: 4.5 bits;  conditional E-value: 0.04
  Proteasome_A_N    7 tFSPdGRL 14  
                       FSPdG+L
      EEA18492.1 1260 AFSPDGKL 1267
                      5******9 PP

  == domain 6  score: 2.8 bits;  conditional E-value: 0.14
  Proteasome_A_N    8 FSPdGR 13  
                      FSPdGR
      EEA18492.1 1303 FSPDGR 1308
                      *****9 PP

  == domain 7  score: 6.3 bits;  conditional E-value: 0.011
  Proteasome_A_N    7 tFSPdGRL 14  
                      +FSPdG+L
      EEA18492.1 1345 VFSPDGKL 1352
                      9******9 PP

  == domain 8  score: 2.3 bits;  conditional E-value: 0.2
  Proteasome_A_N    7 tFSPdGRL 14  
                       FSP G+L
      EEA18492.1 1387 AFSPNGKL 1394
                      6******9 PP

>> PD40  WD40-like Beta Propeller Repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0      0.11        74      15      22 ..     966     973 ..     960     975 .. 0.84
   2 ?    3.5   0.0      0.11        73      15      22 ..    1008    1015 ..    1001    1017 .. 0.84
   3 ?    4.7   0.0     0.043        30      14      24 ..    1049    1059 ..    1042    1059 .. 0.83
   4 ?    0.7   0.0      0.79   5.4e+02      11      24 ..    1172    1185 ..    1168    1185 .. 0.82
   5 ?    3.3   0.0      0.12        84      15      22 ..    1218    1225 ..    1215    1227 .. 0.82
   6 ?    3.5   0.0      0.11        74      15      22 ..    1260    1267 ..    1257    1269 .. 0.81
   7 ?    5.9   0.0     0.019        13      13      29 ..    1300    1316 ..    1294    1319 .. 0.79
   8 ?    2.5   0.0      0.22   1.5e+02      15      22 ..    1345    1352 ..    1341    1354 .. 0.81
   9 ?    2.1   0.0      0.28   1.9e+02      15      24 ..    1387    1396 ..    1385    1396 .. 0.90
  10 ?   -1.6   0.1       4.2   2.9e+03      13      23 ..    1511    1521 ..    1506    1524 .. 0.77

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.11
                 EE-TTSSE CS
        PD40  15 sfSPDGkr 22 
                 +fSPDGk 
  EEA18492.1 966 AFSPDGKL 973
                 8*****96 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.11
                  EE-TTSSE CS
        PD40   15 sfSPDGkr 22  
                  +fSPDGk 
  EEA18492.1 1008 AFSPDGKL 1015
                  8*****96 PP

  == domain 3  score: 4.7 bits;  conditional E-value: 0.043
                  EEE-TTSSEEE CS
        PD40   14 PsfSPDGkrla 24  
                    fSPDGk +a
  EEA18492.1 1049 VMFSPDGKLIA 1059
                  56******997 PP

  == domain 4  score: 0.7 bits;  conditional E-value: 0.79
                  EEEEEE-TTSSEEE CS
        PD40   11 egaPsfSPDGkrla 24  
                  + a++fS DGk +a
  EEA18492.1 1172 ISAIAFSLDGKLMA 1185
                  6799*******886 PP

  == domain 5  score: 3.3 bits;  conditional E-value: 0.12
                  EE-TTSSE CS
        PD40   15 sfSPDGkr 22  
                  +fSPDGk 
  EEA18492.1 1218 AFSPDGKL 1225
                  8*****96 PP

  == domain 6  score: 3.5 bits;  conditional E-value: 0.11
                  EE-TTSSE CS
        PD40   15 sfSPDGkr 22  
                  +fSPDGk 
  EEA18492.1 1260 AFSPDGKL 1267
                  8*****96 PP

  == domain 7  score: 5.9 bits;  conditional E-value: 0.019
                  EEEE-TTSSEEEEEEEC CS
        PD40   13 aPsfSPDGkrlaFsSdR 29  
                    +fSPDG+  + sS+ 
  EEA18492.1 1300 TLAFSPDGRFVVVSSSE 1316
                  569*****999988875 PP

  == domain 8  score: 2.5 bits;  conditional E-value: 0.22
                  EE-TTSSE CS
        PD40   15 sfSPDGkr 22  
                   fSPDGk 
  EEA18492.1 1345 VFSPDGKL 1352
                  7*****96 PP

  == domain 9  score: 2.1 bits;  conditional E-value: 0.28
                  EE-TTSSEEE CS
        PD40   15 sfSPDGkrla 24  
                  +fSP+Gk +a
  EEA18492.1 1387 AFSPNGKLIA 1396
                  8******997 PP

  == domain 10  score: -1.6 bits;  conditional E-value: 4.2
                  EEEE-TTSSEE CS
        PD40   13 aPsfSPDGkrl 23  
                  a sfS DGk l
  EEA18492.1 1511 ALSFSLDGKLL 1521
                  569*****765 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.9   0.0   4.6e-12   3.2e-09       3     142 ..     405     561 ..     403     593 .. 0.77

  Alignments for each domain:
  == domain 1  score: 36.9 bits;  conditional E-value: 4.6e-12
                 EEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-......-HCHHHCCCCTS--SSS-C........CHHHHCCSCCCEE...... CS
       NACHT   3 vilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgna...rsladllfsqlpepaapvse........vwavllelperlL...... 84 
                  +l+G aG GK+t  + +a+ +  +   +     +Ff++ +e  rs+ a   ++++ +l  + p ++a v+           + + e++e+l       
  EEA18492.1 405 FWLKGMAGTGKSTISRTVAESLNMEGKLG----ASFFFKRGESDRSSVAmffTTICAQLLTKIPSLIAYVELaidadpniSDKSMGEQFEKLIcrplsh 499
                 79********************9888444....69***********99966666666666666666666655777777774445555555555788888 PP

                 ............EEEE-STT-SS-TCH.........HHHHHCTTTTT--EEEEEEECCCHHHHCTTSSCE CS
       NACHT  85 ............lilDglDelvtdlgqkekqpvrtlLselirkkllpeasllltvrpralrdleeqleea 142
                             +++D+lDe++++ +      + +lL +  r k  p+ ++++t+rp++   ++++++  
  EEA18492.1 500 irdqdpqtpkfiFVIDALDECAQEGDT-----LLHLL-SQTRNKWSPSLKIFITSRPEQG--IRSGFANI 561
                 899999999999**********97666.....67777.5556679*************99..88877765 PP

>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.6   0.2   1.7e-11   1.2e-08       4     228 ..      11     304 ..       8     309 .. 0.72

  Alignments for each domain:
  == domain 1  score: 34.6 bits;  conditional E-value: 1.7e-11
                 EEESSHHHHHHHHHH..EEEEEEEEEE..TTEEEEEEEETTEEEEEEE--...SSHHHHHHHHHHHHHHHC.--SEEEEEEEEEES..STTT-TT-EEE CS
   PNP_UDP_1   4 iivgspgevellaes..pleetpfgre.grgfkfvtGtlkgkpvvivstG...iGkpnaavvaeirllkef.gvkaiiriGtaGgl..npdlkvGDvvi 93 
                  i++   e+ +  e   ++ e p++ + + + ++++G+l++++vvi+       G+ +aa   ++ +l +f +v+  + +G+ Gg+  + d+++GD+v+
  EEA18492.1  11 WICALSTEYVAAQELldDEHEPPEFVSpNDTNDYTLGRLGKHNVVIAVLPngeYGTASAA-SVATNMLNSFpNVRIGLLVGIGGGVptKRDIRLGDIVV 108
                 5677775555555554445555555556***********999999999888888******.99999***9*899999**********99********** PP

                 EEEEEESSSCCGCCTHHCC............................................................TCCCCTTSSEE--HHHHHHH CS
   PNP_UDP_1  94 pddainfdgrsplygpkee............................................................gqyfpdsydapadpelrall 132
                 +   +  +g+   y ++                                                              g                +l 
  EEA18492.1 109 SVP-CEGEGGVFQYDFGKTiqeqafqsmrflnqpptmlrgavmgiqaqherkghrleeaietilennprlcrkykrphpG--------------SDRLF 192
                 **9.333333333332222456677789999999*******************************866666666544440..............33333 PP

                 HH.........................CHHTTTTTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTBETT CS
   PNP_UDP_1 133 ke.........................aaealgikvhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArelgipfaairvvsdlaaggad 206
                 k+                         a ++ ++ +h+G++a++++   + + ++rl ++  + + eME+a +      ++ p+++ir++ d      d
  EEA18492.1 193 KAdithtgacadfctnnpsylverqerAEHEDNPAIHYGLIASGNQLMKDAVTRDRLAAEKDVLCFEMEAAGL-----MNHFPCLVIRGICD----YSD 282
                 333333333333444455544444433555555************************************9976.....5789********99....333 PP

                 CTCH.HCCCHHHHHHHHHHHHH CS
   PNP_UDP_1 207 aeatheeveefaqeaaknaaal 228
                  + +++ ++ +a +aa  a+ l
  EEA18492.1 283 SHKNKAWQGYAAMAAAAYAKDL 304
                 3333344444444444444444 PP

>> Ret2_MD  RNA editing 3' terminal uridylyl transferase 2 middle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.62   4.3e+02      60      79 ..     959     978 ..     949     985 .. 0.81
   2 ?    4.1   0.0      0.09        62      55      80 ..     996    1021 ..     977    1029 .. 0.74
   3 ?    2.0   0.0       0.4   2.8e+02      59      79 ..    1042    1062 ..    1026    1072 .. 0.82
   4 ?   -2.1   0.0       7.5   5.1e+03      58      81 ..    1125    1148 ..    1116    1155 .. 0.79
   5 ?   -1.4   0.0       4.5   3.1e+03      61      79 ..    1170    1188 ..    1165    1199 .. 0.81
   6 ?    4.3   0.0     0.074        51      57      84 ..    1208    1234 ..    1195    1242 .. 0.79
   7 ?    2.5   0.0      0.27   1.8e+02      59      79 ..    1252    1272 ..    1234    1281 .. 0.83
   8 ?    6.8   0.0     0.012       8.6      59      89 ..    1294    1324 ..    1283    1327 .. 0.87
   9 ?   -0.6   0.0       2.5   1.7e+03      60      78 ..    1338    1356 ..    1328    1363 .. 0.80
  10 ?   -0.7   0.0       2.8   1.9e+03      62      84 ..    1382    1404 ..    1372    1408 .. 0.82

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.62
     Ret2_MD  60 eqaieaigllPdGkiltkgm 79 
                  + + a+++ PdGk+++ g 
  EEA18492.1 959 SKPVKAVAFSPDGKLVASGS 978
                 56789*********998875 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.09
     Ret2_MD   55 qvsskeqaieaigllPdGkiltkgmr 80  
                   + ++ + + a+++ PdGk+++ g  
  EEA18492.1  996 TIEAHSESVKAVAFSPDGKLVASGSD 1021
                  445667899***********998865 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.4
     Ret2_MD   59 keqaieaigllPdGkiltkgm 79  
                  + q + a+ + PdGk+++ g 
  EEA18492.1 1042 HSQSVHAVMFSPDGKLIASGS 1062
                  67899***********99875 PP

  == domain 4  score: -2.1 bits;  conditional E-value: 7.5
     Ret2_MD   58 skeqaieaigllPdGkiltkgmre 81  
                  ++ ++i  +++ Pd k+++ g  +
  EEA18492.1 1125 THSKMILIVAFSPDCKLVASGSDD 1148
                  567899999*******99988655 PP

  == domain 5  score: -1.4 bits;  conditional E-value: 4.5
     Ret2_MD   61 qaieaigllPdGkiltkgm 79  
                  + i ai++  dGk+++ g 
  EEA18492.1 1170 HWISAIAFSLDGKLMASGS 1188
                  56899**********9886 PP

  == domain 6  score: 4.3 bits;  conditional E-value: 0.074
     Ret2_MD   57 sskeqaieaigllPdGkiltkgmredyt 84  
                   s  + ++a+++ PdGk++  g   d t
  EEA18492.1 1208 ESYSDSVNAVAFSPDGKLVVSGLE-DNT 1234
                  577899************998874.444 PP

  == domain 7  score: 2.5 bits;  conditional E-value: 0.27
     Ret2_MD   59 keqaieaigllPdGkiltkgm 79  
                  + + ++a+++ PdGk+++ g 
  EEA18492.1 1252 HSDSVNAVAFSPDGKLVASGS 1272
                  67899**********998775 PP

  == domain 8  score: 6.8 bits;  conditional E-value: 0.012
     Ret2_MD   59 keqaieaigllPdGkiltkgmredytrdvld 89  
                  + q+i+++++ PdG+ +  +  ed +  + d
  EEA18492.1 1294 HSQMIDTLAFSPDGRFVVVSSSEDRIVKLWD 1324
                  689*********************9877766 PP

  == domain 9  score: -0.6 bits;  conditional E-value: 2.5
     Ret2_MD   60 eqaieaigllPdGkiltkg 78  
                   + + a+ + PdGk+++ g
  EEA18492.1 1338 SHWVRAVVFSPDGKLVASG 1356
                  566899********99877 PP

  == domain 10  score: -0.7 bits;  conditional E-value: 2.8
     Ret2_MD   62 aieaigllPdGkiltkgmredyt 84  
                   ++++++ P+Gk+++ g  +  +
  EEA18492.1 1382 LVNTVAFSPNGKLIASGSSDKTV 1404
                  689***********998776655 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.4   0.0   7.8e-11   5.4e-08      12     164 ..     388     537 ..     383     546 .. 0.68

  Alignments for each domain:
  == domain 1  score: 33.4 bits;  conditional E-value: 7.8e-11
      AAA_16  12 Llsalervrsgrp..elvllsGesGvGKsslvrellralekd.....ggiflrgkcdqlesaipysalaqalareellrqlldeaesaeleawreklee 103
                 L++ ++ ++++    ++  l G++G+GKs++ r+++++l+ +      ++f rg+ d++         + ++++ ++++qll++  s + ++   ++++
  EEA18492.1 388 LRRQIREWAENAQgkSIFWLKGMAGTGKSTISRTVAESLNMEgklgaSFFFKRGESDRS--------SVAMFFT-TICAQLLTKIPS-LIAYVELAIDA 476
                 44444433333333499**********************99988843344477777777........7777855.889999988444.88888888887 PP

      AAA_16 104 alaavpelagaeasrllellkrllallsrder..p.lvlvlDdlqwadeaslqllaaLlrlles 164
                   +++++  g   +++  l+ r l+ ++ +++  p +++v+D l+   ++  +ll +L ++++ 
  EEA18492.1 477 DPNISDKSMG---EQFEKLICRPLSHIRDQDPqtPkFIFVIDALDECAQEGDTLLHLLSQTRNK 537
                 7774444444...44444444444333332222235*******************999998775 PP

>> DUF4784  Domain of unknown function (DUF4784)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0      0.08        55     324     356 ..     976    1009 ..     958    1017 .. 0.79
   2 ?    2.8   0.0     0.068        47     316     361 ..    1010    1054 ..     996    1060 .. 0.71
   3 ?    1.7   0.0      0.14        97     321     353 ..    1058    1090 ..    1054    1098 .. 0.78
   4 ?    4.9   0.0     0.015        11     322     361 ..    1100    1138 ..    1092    1160 .. 0.82
   5 ?    5.1   0.0     0.013       9.3     321     359 ..    1184    1220 ..    1177    1235 .. 0.85
   6 ?    0.8   0.0      0.26   1.8e+02     319     390 ..    1265    1330 ..    1240    1346 .. 0.65
   7 ?    4.3   0.0     0.024        16     321     361 ..    1395    1433 ..    1382    1474 .. 0.76
   8 ?   -3.0   0.0       3.8   2.7e+03     326     346 ..    1484    1504 ..    1478    1511 .. 0.76

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.08
     DUF4784  324 kag.ktelrLlnpeaeslgeplatvpnaavsvat 356 
                   ++ +   +L+np+++sl++++ + ++++  va 
  EEA18492.1  976 SGSdDKTVKLWNPATGSLQQTIEAHSESVKAVAF 1009
                  443367799**************99999888754 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.068
     DUF4784  316 kagGYivskag.ktelrLlnpeaeslgeplatvpnaavsvatllskd 361 
                     G +v  ++ + + rL+npe++sl ++l   ++++  v  + s+d
  EEA18492.1 1010 SPDGKLVASGSdDRNVRLWNPETGSLLQTLKGHSQSVHAV--MFSPD 1054
                  555666666644789***************9999888777..45665 PP

  == domain 3  score: 1.7 bits;  conditional E-value: 0.14
     DUF4784  321 ivskagktelrLlnpeaeslgeplatvpnaavs 353 
                  i+s +g+   +L++p+++sl++++   ++ +  
  EEA18492.1 1058 IASGSGDKTVKLWDPATGSLQQTFKGHSELVNA 1090
                  455568999***************877665555 PP

  == domain 4  score: 4.9 bits;  conditional E-value: 0.015
     DUF4784  322 vska.gktelrLlnpeaeslgeplatvpnaavsvatllskd 361 
                  v  +  +t ++L++ +++sl+++  t ++  ++va   s+d
  EEA18492.1 1100 VASGsNDTTFKLWDLATGSLQQTYVTHSKMILIVAF--SPD 1138
                  4444259*******************9999888854..555 PP

  == domain 5  score: 5.1 bits;  conditional E-value: 0.013
     DUF4784  321 ivskagktelrLlnpeaeslgeplatvpnaavsvatlls 359 
                  ++s +g+   +L++p+++sl+++l  +++++  va   s
  EEA18492.1 1184 MASGSGDKTVKLWDPATGSLQQTLESYSDSVNAVAF--S 1220
                  456678999********************9988854..4 PP

  == domain 6  score: 0.8 bits;  conditional E-value: 0.26
     DUF4784  319 GYivskag.ktelrLlnpeaeslgeplatvpnaavsvatllskdldklkiyvlfdvsekgrliqvYDlakksw 390 
                  G +v  ++ +t ++L++p+++sl ++l   +  +++ +   s+d      +v ++ s + r ++ +D a+ ++
  EEA18492.1 1265 GKLVASGSfDTAIKLWDPATGSLLQTLKGHS--QMIDTLAFSPD----GRFVVVS-SSEDRIVKLWDSATGNL 1330
                  5556666568999999999999988886543..44444455666....3344444.44556666666666554 PP

  == domain 7  score: 4.3 bits;  conditional E-value: 0.024
     DUF4784  321 ivskagktelrLlnpeaeslgeplatvpnaavsvatllskd 361 
                  i+s +++   rL++ +++sl++ +   ++++ +va +   d
  EEA18492.1 1395 IASGSSDKTVRLWDLATGSLQQIFKSHSESVNIVAFSS--D 1433
                  445557899*********************99996533..3 PP

  == domain 8  score: -3.0 bits;  conditional E-value: 3.8
     DUF4784  326 gktelrLlnpeaeslgeplat 346 
                  ++   +L++p++++l+++l  
  EEA18492.1 1484 SDKTAKLWDPATGNLQQTLDG 1504
                  566679***********9865 PP

>> IKI3  IKI3 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.7   0.0    0.0045       3.1     234     275 ..     979    1021 ..     964    1026 .. 0.85
   2 ?    2.7   0.0     0.036        25     234     277 ..    1021    1065 ..    1014    1072 .. 0.84
   3 ?    2.7   0.0     0.036        25     193     272 ..    1195    1270 ..    1180    1281 .. 0.64
   4 !   10.1   0.4   0.00021      0.14     219     331 ..    1306    1450 ..    1299    1453 .. 0.73

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0045
                  XXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        IKI3  234 erralrvyere.gaLdsvsekvdgleeaLaWrPsGsliAstqr 275 
                  + ++++ ++   g L+++ e+ + + +a+a+ P G+l+As   
  EEA18492.1  979 DDKTVKLWNPAtGSLQQTIEAHSESVKAVAFSPDGKLVASGSD 1021
                  5799*****876***************************9765 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.036
                  XXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        IKI3  234 erralrvyere.gaLdsvsekvdgleeaLaWrPsGsliAstqrkk 277 
                  + r +r ++ e g L ++    +++ +a+ + P G+liAs   +k
  EEA18492.1 1021 DDRNVRLWNPEtGSLLQTLKGHSQSVHAVMFSPDGKLIASGSGDK 1065
                  589******99899999999899999*************977644 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.036
                  XXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXX CS
        IKI3  193 lrdptlpvdegkls.lddskvtIsWRGDgeYfavssleaetgerralrvyerega.LdsvsekvdgleeaLaWrPsGsliAs 272 
                  l dp +   +++l+   ds   ++   Dg+ ++vs le       +++ +++    L+++ e  + + +a+a+ P G+l+As
  EEA18492.1 1195 LWDPATGSLQQTLEsYSDSVNAVAFSPDGK-LVVSGLE-----DNTVKLWDSATSiLQQSLEGHSDSVNAVAFSPDGKLVAS 1270
                  455555544555555666666666666666.4566662.....346688888766577777877777778888888888886 PP

  == domain 4  score: 10.1 bits;  conditional E-value: 0.00021
                  XXXXXXXXXXXXXXX.....................................XXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        IKI3  219 DgeYfavssleaetg.....................................erralrvyere.gaLdsvsekvdgleeaLaWrPsGsliAstqrkk 277 
                  Dg++++vss e  ++                                       ++++ ++   g L ++    + l +++a+ P+G+liAs  ++k
  EEA18492.1 1306 DGRFVVVSSSEDRIVklwdsatgnlqqslkghshwvravvfspdgklvasgsFDTTIKLWNLAtGSLLQTLKGHSLLVNTVAFSPNGKLIASGSSDK 1402
                  6666666666555555555555555555555555555555555555555555567788888655888888888888899************987733 PP

                  XXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXX.XXXXXXXXXX CS
        IKI3  278 dksldvvfFErNGLrhgefslrlekeeeevqsLaWsadSevLav.rledrvqlwt 331 
                      +v ++    L  g+++  +++++e+v+ +a s+dS++ a  ++   v+lw 
  EEA18492.1 1403 ----TVRLWD---LATGSLQQIFKSHSESVNIVAFSSDSKLVASgSVDKTVKLWD 1450
                  ....567776...999***9999999**************999977788899996 PP

>> Cytochrom_D1  Cytochrome D1 heme domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0      0.44   3.1e+02      39      95 ..     963    1020 ..     944    1021 .. 0.75
   2 !    5.2   0.0    0.0094       6.5      12      96 ..    1020    1105 ..    1015    1129 .. 0.81
   3 ?    4.9   0.0     0.012       8.1      13     115 ..    1189    1291 ..    1182    1300 .. 0.78
   4 !   10.5   0.0   0.00023      0.16      12     114 ..    1230    1333 ..    1219    1354 .. 0.88
   5 !    7.1   0.0    0.0025       1.7      16      96 ..    1276    1358 ..    1268    1376 .. 0.81
   6 ?    4.9   0.0     0.011       7.9      26     115 ..    1371    1460 ..    1359    1480 .. 0.85

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.44
                    EEEE-TT.SSEEEEEETTSEEEEEESSSSSEEEEEE-SSEE.EEEEE--TTSEEEEEE CS
  Cytochrom_D1   39 isrvfasdgRyvyvigRDgkvtliDLwakeivaevkiGlna.rsvavSqddryvivgn 95  
                     ++ f++dg++v   + D +v+l    +    +++++ +++ + va S d+++v+ g+
    EEA18492.1  963 KAVAFSPDGKLVASGSDDKTVKLWNPATGSLQQTIEAHSESvKAVAFSPDGKLVASGS 1020
                    567899999999888888777766666666999999999983579999****999885 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0094
                    GGGTEEEEEETTT-SEEEEEE-STTEEEEEE-TT.SSEEEEEETTSEEEEEESSSSSEEEEEE-SSEEEE.EEE--TTSEEEEEEE CS
  Cytochrom_D1   12 rdagkvalldgdskeilavletgyalHisrvfasdgRyvyvigRDgkvtliDLwakeivaevkiGlnars.vavSqddryvivgnY 96  
                    +d+ +v+l + ++ + l++l+++ +   +++f++dg+++   + D +v+l D  +    ++ k  ++  + va S d+++v+ g+ 
    EEA18492.1 1020 SDDRNVRLWNPETGSLLQTLKGHSQSVHAVMFSPDGKLIASGSGDKTVKLWDPATGSLQQTFKGHSELVNaVAFSLDGKLVASGSN 1105
                    5788999999999999999999987644689*****************999999999999999888865438999*****999974 PP

  == domain 3  score: 4.9 bits;  conditional E-value: 0.012
                    GGTEEEEEETTT-SEEEEEE-STTEEEEEE-TT.SSEEEEEETTSEEEEEESSSSSEEEEEE-SSEEEE.EEE--TTSEEEEEEEETTEEEEEET CS
  Cytochrom_D1   13 dagkvalldgdskeilavletgyalHisrvfasdgRyvyvigRDgkvtliDLwakeivaevkiGlnars.vavSqddryvivgnYlPgqlvilda 106 
                    ++  v+l d  + +  ++le+  +   ++ f++dg++v     D +v+l D  +    + ++  +++ + va S d+++v+ g++    +++ d 
    EEA18492.1 1189 GDKTVKLWDPATGSLQQTLESYSDSVNAVAFSPDGKLVVSGLEDNTVKLWDSATSILQQSLEGHSDSVNaVAFSPDGKLVASGSFD-TAIKLWDP 1282
                    56778888888888888899988888899999999999888899999999988877888888878887547899999999999986.45677777 PP

                    TT--EEEEE CS
  Cytochrom_D1  107 etLelvkvi 115 
                     t +l++++
    EEA18492.1 1283 ATGSLLQTL 1291
                    776666665 PP

  == domain 4  score: 10.5 bits;  conditional E-value: 0.00023
                    GGGTEEEEEETTT-SEEEEEE-STTEEEEEE-TT.SSEEEEEETTSEEEEEESSSSSEEEEEE-SSEEE.EEEE--TTSEEEEEEEETTEEEEEE CS
  Cytochrom_D1   12 rdagkvalldgdskeilavletgyalHisrvfasdgRyvyvigRDgkvtliDLwakeivaevkiGlnar.svavSqddryvivgnYlPgqlvild 105 
                     ++  v+l d+ +    + le++ +   ++ f++dg++v   + D+ ++l D  +   ++++k  ++ +  +a S d+r+v+v++ +   +++ d
    EEA18492.1 1230 LEDNTVKLWDSATSILQQSLEGHSDSVNAVAFSPDGKLVASGSFDTAIKLWDPATGSLLQTLKGHSQMIdTLAFSPDGRFVVVSSSEDRIVKLWD 1324
                    567899999999999999********99**********************999999999999988888735899***********9999999999 PP

                    TTT--EEEE CS
  Cytochrom_D1  106 aetLelvkv 114 
                    + t +l + 
    EEA18492.1 1325 SATGNLQQS 1333
                    999777665 PP

  == domain 5  score: 7.1 bits;  conditional E-value: 0.0025
                    EEEEEETTT-SEEEEEE-STTEEEEEE-TT.SSEEEEEE.TTSEEEEEESSSSSEEEEEE-SSE.EEEEEE--TTSEEEEEEE CS
  Cytochrom_D1   16 kvalldgdskeilavletgyalHisrvfasdgRyvyvig.RDgkvtliDLwakeivaevkiGln.arsvavSqddryvivgnY 96  
                     ++l d  + + l++l+++ ++  +  f++dgR+v v +  D  v+l D  + +  + +k  +   r v  S d+++v+ g++
    EEA18492.1 1276 AIKLWDPATGSLLQTLKGHSQMIDTLAFSPDGRFVVVSSsEDRIVKLWDSATGNLQQSLKGHSHwVRAVVFSPDGKLVASGSF 1358
                    6788888999999999999999999**********998615666777777777788888755543689999999999999987 PP

  == domain 6  score: 4.9 bits;  conditional E-value: 0.011
                    SEEEEEE-STTEEEEEE-TT.SSEEEEEETTSEEEEEESSSSSEEEEEE-SSEEEE.EEE--TTSEEEEEEEETTEEEEEETTT--EEEEE CS
  Cytochrom_D1   26 eilavletgyalHisrvfasdgRyvyvigRDgkvtliDLwakeivaevkiGlnars.vavSqddryvivgnYlPgqlvildaetLelvkvi 115 
                    + l++l+++  l  ++ f+++g+++   + D +v l DL +    +  k  +++ + va S d ++v+ g+    ++++ d+ t +l++++
    EEA18492.1 1371 SLLQTLKGHSLLVNTVAFSPNGKLIASGSSDKTVRLWDLATGSLQQIFKSHSESVNiVAFSSDSKLVASGSV-DKTVKLWDSTTGSLLQTL 1460
                    56777888888888999*************************************9945899*****999985.578999999998888765 PP

>> DUF5122  Domain of unknown function (DUF5122) beta-propeller
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.0      0.18   1.3e+02       2      13 ..     969     980 ..     968     988 .. 0.88
   2 ?    3.6   0.0      0.12        83       2      13 ..    1011    1022 ..    1010    1030 .. 0.85
   3 ?    2.0   0.1      0.37   2.6e+02       2      13 ..    1053    1064 ..    1052    1069 .. 0.88
   4 ?   -1.0   0.1       3.4   2.4e+03       3      11 ..    1096    1104 ..    1096    1109 .. 0.71
   5 ?    2.9   0.0       0.2   1.4e+02       2      10 ..    1221    1229 ..    1220    1236 .. 0.89
   6 ?    6.1   0.0     0.019        13       2      13 ..    1263    1274 ..    1262    1280 .. 0.90
   7 ?   -0.9   0.0       3.1   2.1e+03       2      13 ..    1305    1316 ..    1304    1322 .. 0.83
   8 ?    6.3   0.0     0.017        12       2      13 ..    1348    1359 ..    1347    1368 .. 0.89
   9 ?    0.6   0.0       1.1   7.3e+02       2      13 ..    1390    1401 ..    1389    1407 .. 0.87

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.18
     DUF5122   2 pDGKIlVaGsft 13 
                 pDGK+++ Gs  
  EEA18492.1 969 PDGKLVASGSDD 980
                 9********976 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.12
     DUF5122    2 pDGKIlVaGsft 13  
                  pDGK+++ Gs  
  EEA18492.1 1011 PDGKLVASGSDD 1022
                  9********987 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.37
     DUF5122    2 pDGKIlVaGsft 13  
                  pDGK+++ Gs  
  EEA18492.1 1053 PDGKLIASGSGD 1064
                  9********975 PP

  == domain 4  score: -1.0 bits;  conditional E-value: 3.4
     DUF5122    3 DGKIlVaGs 11  
                  DGK+++ Gs
  EEA18492.1 1096 DGKLVASGS 1104
                  888888776 PP

  == domain 5  score: 2.9 bits;  conditional E-value: 0.2
     DUF5122    2 pDGKIlVaG 10  
                  pDGK++V G
  EEA18492.1 1221 PDGKLVVSG 1229
                  9******99 PP

  == domain 6  score: 6.1 bits;  conditional E-value: 0.019
     DUF5122    2 pDGKIlVaGsft 13  
                  pDGK+++ Gsf 
  EEA18492.1 1263 PDGKLVASGSFD 1274
                  9**********8 PP

  == domain 7  score: -0.9 bits;  conditional E-value: 3.1
     DUF5122    2 pDGKIlVaGsft 13  
                  pDG+ +V+ s+ 
  EEA18492.1 1305 PDGRFVVVSSSE 1316
                  9***99999875 PP

  == domain 8  score: 6.3 bits;  conditional E-value: 0.017
     DUF5122    2 pDGKIlVaGsft 13  
                  pDGK+++ Gsf 
  EEA18492.1 1348 PDGKLVASGSFD 1359
                  9**********8 PP

  == domain 9  score: 0.6 bits;  conditional E-value: 1.1
     DUF5122    2 pDGKIlVaGsft 13  
                  p+GK+++ Gs+ 
  EEA18492.1 1390 PNGKLIASGSSD 1401
                  89*******997 PP

>> DUF5046  Domain of unknown function (DUF5046)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.1   0.0    0.0096       6.6      57     113 ..    1096    1161 ..    1027    1176 .. 0.62
   2 ?    5.8   0.0     0.012         8      25      81 ..    1103    1161 ..    1086    1203 .. 0.66
   3 ?   -0.8   0.0       1.2   8.1e+02      28     114 ..    1190    1288 ..    1179    1318 .. 0.55
   4 ?   -0.5   0.0      0.98   6.8e+02      58     114 ..    1307    1373 ..    1267    1387 .. 0.62
   5 !   10.5   0.0   0.00044       0.3      55     117 ..    1388    1460 ..    1349    1470 .. 0.67

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0096
     DUF5046   57 PGavvlwnsgedsryelidletGektpvy..........dvdardktvavyatdgilrvydkttGal 113 
                   G +v ++s +d +++l+dl+tG  +  y              + k va  + d i++++d  tG+l
  EEA18492.1 1096 DGKLVASGS-NDTTFKLWDLATGSLQQTYvthskmilivAFSPDCKLVASGSDDKIIKLWDLGTGNL 1161
                  455555544.345566666666655555522222111111112233344444444444444444444 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.012
     DUF5046   25 rtedgryelidlastedsellatfdrsvs..tyaPGavvlwnsgedsryelidletGek 81  
                   ++d+ ++l dla++  ++   t  + ++   + P + ++    +d+  +l+dl tG+ 
  EEA18492.1 1103 GSNDTTFKLWDLATGSLQQTYVTHSKMILivAFSPDCKLVASGSDDKIIKLWDLGTGNL 1161
                  34666666666666666665666665543114666666665555666666666666654 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 1.2
     DUF5046   28 dgryelidlastedsellatfdrsvst..yaP.Gavvlwnsgedsryelidlet........Gektpvydvda..rdktvavyatdgilrvydkttG 111 
                  d   +l d a++  ++ l  +  sv+   + P G +v+++  ed++ +l+d +t        G   +v  v    + k va  + d +++++d  tG
  EEA18492.1 1190 DKTVKLWDPATGSLQQTLESYSDSVNAvaFSPdGKLVVSG-LEDNTVKLWDSATsilqqsleGHSDSVNAVAFspDGKLVASGSFDTAIKLWDPATG 1285
                  4555556666665555566665555531144423344333.34445555555541111111133333333322113445666666666677777777 PP

     DUF5046  112 all 114 
                   ll
  EEA18492.1 1286 SLL 1288
                  666 PP

  == domain 4  score: -0.5 bits;  conditional E-value: 0.98
     DUF5046   58 GavvlwnsgedsryelidletGektp.vy.......dv..dardktvavyatdgilrvydkttGall 114 
                  G  v+  s ed   +l+d +tG+ +  ++        v    + k va  + d ++++++  tG ll
  EEA18492.1 1307 GRFVVVSSSEDRIVKLWDSATGNLQQsLKghshwvrAVvfSPDGKLVASGSFDTTIKLWNLATGSLL 1373
                  6677777778888888888888754313232222222211223344555666666666666666666 PP

  == domain 5  score: 10.5 bits;  conditional E-value: 0.00044
     DUF5046   55 yaP.GavvlwnsgedsryelidletGektpvy..........dvdardktvavyatdgilrvydkttGalltdv 117 
                  + P G ++ ++s  d++ +l+dl+tG  + ++              ++k va  ++d +++++d ttG ll   
  EEA18492.1 1388 FSPnGKLIASGS-SDKTVRLWDLATGSLQQIFkshsesvnivAFSSDSKLVASGSVDKTVKLWDSTTGSLLQTL 1460
                  455244444444.57899*********999985555533222223567778888999999*********99765 PP

>> DUF1513  Protein of unknown function (DUF1513)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0     0.049        34     221     278 ..     964    1022 ..     960    1049 .. 0.78
   2 ?   -0.2   0.0      0.59   4.1e+02     239     279 ..    1065    1107 ..    1035    1129 .. 0.51
   3 ?   -0.3   0.0      0.66   4.6e+02     219     276 ..    1088    1146 ..    1077    1164 .. 0.70
   4 ?    4.9   0.0     0.017        12     213     281 ..    1166    1236 ..    1137    1261 .. 0.72
   5 !    5.8   0.0    0.0091       6.3     219     276 ..    1298    1357 ..    1267    1379 .. 0.81
   6 ?    0.6   0.0      0.35   2.4e+02     221     277 ..    1385    1442 ..    1374    1468 .. 0.66

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.049
     DUF1513  221 svavdsegrlvavtsPrgnlvavwdlasgelleeaal..adaagvaaaksgflvssGqgk 278 
                  +va++ +g+lva  s   ++v +w+ a+g+l ++++   + + +va  ++g lv+sG+++
  EEA18492.1  964 AVAFSPDGKLVASGS-DDKTVKLWNPATGSLQQTIEAhsESVKAVAFSPDGKLVASGSDD 1022
                  699999999996666.56899********99987654216899*************9975 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.59
     DUF1513  239 nlvavwdlasgelleeaa..ladaagvaaaksgflvssGqgkl 279 
                  ++v +wd a+g+l ++ +   + + +va   +g lv+sG++++
  EEA18492.1 1065 KTVKLWDPATGSLQQTFKghSELVNAVAFSLDGKLVASGSNDT 1107
                  4555666555555544331123344555555555555555442 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.66
     DUF1513  219 igsvavdsegrlvavtsPrgnlvavwdlasgelleeaalad..aagvaaaksgflvssGq 276 
                  + +va++ +g+lva  s+   ++ +wdla+g+l ++   +   +  va  ++  lv+sG+
  EEA18492.1 1088 VNAVAFSLDGKLVASGSND-TTFKLWDLATGSLQQTYVTHSkmILIVAFSPDCKLVASGS 1146
                  5689999999999887776.57899******99876544330033334444445666665 PP

  == domain 4  score: 4.9 bits;  conditional E-value: 0.017
     DUF1513  213 aalagYigsvavdsegrlvavtsPrgnlvavwdlasgelleeaa.lad.aagvaaaksgflvssGqgk.lve 281 
                  +   ++i ++a++ +g+l+a  s   ++v +wd a+g+l ++ +  +d + +va  ++g lv sG ++ +v+
  EEA18492.1 1166 EGHSHWISAIAFSLDGKLMASGSG-DKTVKLWDPATGSLQQTLEsYSDsVNAVAFSPDGKLVVSGLEDnTVK 1236
                  4557899********999865554.5799********99876431444378999999998888887653333 PP

  == domain 5  score: 5.8 bits;  conditional E-value: 0.0091
     DUF1513  219 igsvavdsegrlvavtsPrgnlvavwdlasgelleeaalad..aagvaaaksgflvssGq 276 
                  i   a++ +gr+v+v+s +  +v +wd+a+g+l ++ + +   + +v+  ++g lv+sG+
  EEA18492.1 1298 IDTLAFSPDGRFVVVSSSEDRIVKLWDSATGNLQQSLKGHShwVRAVVFSPDGKLVASGS 1357
                  5567999*************************9987654332267788888887888776 PP

  == domain 6  score: 0.6 bits;  conditional E-value: 0.35
     DUF1513  221 svavdsegrlvavtsPrgnlvavwdlasgelle..eaaladaagvaaaksgflvssGqg 277 
                   va++ +g+l+a  s + ++v +wdla+g+l +  + + + +  va  +++ lv+sG+ 
  EEA18492.1 1385 TVAFSPNGKLIASGS-SDKTVRLWDLATGSLQQifKSHSESVNIVAFSSDSKLVASGSV 1442
                  588888888885554.5678899999999887622344455555666666677777763 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   1.5e-05      0.01       3     113 ..     407     551 ..     405     557 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.5e-05
                 EESSTTSSHHHHHHHHHHHHTHE.....................EEEEETTTCSSS......................STTHHHHHHHHHHHHHHHTS. CS
         AAA   3 lyGppGtGKTllakavakelgve.....................fleisgsellsk......................yvgesekkirelfkeakeka. 57 
                 l G  GtGK+++ + va++l++e                     f+++ +++ll k                      + ++ ek i   +++++ +  
  EEA18492.1 407 LKGMAGTGKSTISRTVAESLNMEgklgasfffkrgesdrssvamFFTTICAQLLTKipsliayvelaidadpnisdksMGEQFEKLICRPLSHIRDQDp 505
                 7799***************97666666666666666667777777777777777679999999*********999997777778889999999999999 PP

                 .TS.EEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTSSSTEEEEEEESSGG CS
         AAA  58 .kp.silfiDEidalaksrsgseseeeervvnqLlteldgvkkkeskvivigatnrpd 113
                  +p  i++iD +d+ a++             ++Ll+ l++ ++k s+ + i +t rp+
  EEA18492.1 506 qTPkFIFVIDALDECAQEG------------DTLLHLLSQTRNKWSPSLKIFITSRPE 551
                 98878999*******9999............888888888888877888888888876 PP

>> MORN_2  MORN repeat variant
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   0.0     0.039        27       8      22 .]     642     656 ..     641     656 .. 0.91
   2 ?   -1.3   0.0       5.9   4.1e+03       7      15 ..    1050    1058 ..    1047    1062 .. 0.81
   3 ?   -0.7   0.0       3.8   2.6e+03       8      20 ..    1261    1273 ..    1258    1274 .. 0.83
   4 ?   -0.0   0.0       2.3   1.6e+03       7      20 ..    1345    1358 ..    1342    1359 .. 0.82
   5 ?   -0.2   0.0       2.5   1.8e+03       8      15 ..    1388    1395 ..    1385    1399 .. 0.84

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.039
      MORN_2   8 YyenGklkeeltYkn 22 
                  +++G+lk+ ++Y+n
  EEA18492.1 642 SDPSGQLKKVIEYQN 656
                 59************9 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 5.9
      MORN_2    7 eYyenGklk 15  
                  ++ ++Gkl 
  EEA18492.1 1050 MFSPDGKLI 1058
                  799****97 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 3.8
      MORN_2    8 YyenGklkeeltY 20  
                  + ++Gkl   +++
  EEA18492.1 1261 FSPDGKLVASGSF 1273
                  89*****988776 PP

  == domain 4  score: -0.0 bits;  conditional E-value: 2.3
      MORN_2    7 eYyenGklkeeltY 20  
                   + ++Gkl   +++
  EEA18492.1 1345 VFSPDGKLVASGSF 1358
                  699*****988776 PP

  == domain 5  score: -0.2 bits;  conditional E-value: 2.5
      MORN_2    8 YyenGklk 15  
                  + +nGkl 
  EEA18492.1 1388 FSPNGKLI 1395
                  89****97 PP

>> Stimulus_sens_1  Stimulus-sensing domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0       3.1   2.1e+03      17      32 ..     960     975 ..     949     978 .. 0.85
   2 ?   -0.5   0.0       2.6   1.8e+03      17      32 ..    1002    1017 ..     997    1021 .. 0.86
   3 ?    3.3   0.0      0.17   1.2e+02       8      32 ..    1034    1059 ..    1028    1062 .. 0.80
   4 ?    3.7   0.0      0.13        92      19      32 ..    1341    1354 ..    1333    1358 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 3.1
  Stimulus_sens_1  17 tetRarlYdpdGkLva 32 
                      ++++a  ++pdGkLva
       EEA18492.1 960 KPVKAVAFSPDGKLVA 975
                      5679999********8 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 2.6
  Stimulus_sens_1   17 tetRarlYdpdGkLva 32  
                       ++++a  ++pdGkLva
       EEA18492.1 1002 ESVKAVAFSPDGKLVA 1017
                       6779999********8 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.17
  Stimulus_sens_1    8 plLrrLvePtet.RarlYdpdGkLva 32  
                        lL  L   ++  +a  ++pdGkL+a
       EEA18492.1 1034 SLLQTLKGHSQSvHAVMFSPDGKLIA 1059
                       5777887777777***********98 PP

  == domain 4  score: 3.7 bits;  conditional E-value: 0.13
  Stimulus_sens_1   19 tRarlYdpdGkLva 32  
                       +Ra +++pdGkLva
       EEA18492.1 1341 VRAVVFSPDGKLVA 1354
                       5************8 PP

>> Lactonase  Lactonase, 7-bladed beta-propeller
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0      0.34   2.4e+02     248     329 ..     964    1037 ..     946    1052 .. 0.63
   2 ?   -2.2   0.0       2.8   1.9e+03     142     158 ..    1043    1059 ..    1031    1082 .. 0.73
   3 ?   -0.9   0.0       1.1   7.5e+02     244     311 ..    1170    1232 ..    1158    1247 .. 0.76
   4 ?    7.1   0.0    0.0042       2.9     249     309 ..    1301    1357 ..    1283    1377 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.34
                  EEEE-TTSSEEEEEETSSTEEEEEEE-TTT--EEEEEEEE-SSS.--EEEE-TTSSEEEEEETTTTEEEEEEEETTTTEEEE CS
   Lactonase  248 eIrlspdgkflyvSnRgadsiavfavdeadgtltlveevstegkfPRdfaldpsgklllvanqksdnvtvferdaetGkLte 329 
                  +++ spdgk  ++S  ++d+ + +  ++a+g+l+++ e+++e       a++p+gkl++ +  ++ nv +   ++etG L +
  EEA18492.1  964 AVAFSPDGKL-VAS-GSDDKTVKLW-NPATGSLQQTIEAHSESV--KAVAFSPDGKLVASGS-DDRNVRLW--NPETGSLLQ 1037
                  5667777765.333.3344444333.377777777666666666..8888899998776654.44555543..566666655 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 2.8
                  STTEEEEEE-TTSSEEE CS
   Lactonase  142 sphaHsvvldpdgkfll 158 
                  s+ +H v ++pdgk ++
  EEA18492.1 1043 SQSVHAVMFSPDGKLIA 1059
                  56789999999999654 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 1.1
                  --EEEEEE-TTSSEEEEEETSSTEEEEEEE-TTT--EEEEEEEE-SSS.--EEEE-TTSSEEEEEETT CS
   Lactonase  244 nsaaeIrlspdgkflyvSnRgadsiavfavdeadgtltlveevstegkfPRdfaldpsgklllvanqk 311 
                   + ++I+ s dgk l++S  g+ ++ +++  +a+g+l+  ++ +++ +     a++p+gkl++ + ++
  EEA18492.1 1170 HWISAIAFSLDGK-LMASGSGDKTVKLWD--PATGSLQ--QTLESYSDSVNAVAFSPDGKLVVSGLED 1232
                  4889999999997.588888888888876..6877765..5566666666899999999999888776 PP

  == domain 4  score: 7.1 bits;  conditional E-value: 0.0042
                  EEE-TTSSEEEEEETSSTEEEEEEE-TTT--EEEEEEEE-SSS.--EEEE-TTSSEEEEEE CS
   Lactonase  249 IrlspdgkflyvSnRgadsiavfavdeadgtltlveevstegkfPRdfaldpsgklllvan 309 
                  ++ spdg+f++vS+ ++d i+ +  d+a+g+l++    + + ++ R  +++p+gkl++ + 
  EEA18492.1 1301 LAFSPDGRFVVVSS-SEDRIVKLW-DSATGNLQQ--SLKGHSHWVRAVVFSPDGKLVASGS 1357
                  5789********98.789999988.688888765..555566889**********999875 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   0.00014     0.096      17      46 ..     401     430 ..     389     452 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00014
      AAA_30  17 gdrvavltGpAGtGKttalkalreaweaag 46 
                 g+ +  l+G AGtGK+t+ ++++e ++ +g
  EEA18492.1 401 GKSIFWLKGMAGTGKSTISRTVAESLNMEG 430
                 4458999****************9999887 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   0.00024      0.17       3      25 ..     407     433 ..     406     547 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00024
      AAA_18   3 ltGtpGvGKttlakeLskrlgf....g 25 
                 l G++G+GK+t+++ ++++l++    g
  EEA18492.1 407 LKGMAGTGKSTISRTVAESLNMegklG 433
                 77*****************99975441 PP

>> APS_kinase  Adenylylsulphate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   0.00016      0.11       4      31 ..     404     431 ..     401     437 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00016
                 EEEEESSTTSSHHHHHHHHHHHHHHTT- CS
  APS_kinase   4 vvwltGlsgsGKstianalekkLvekgi 31 
                 ++wl G++g+GKsti+++++++L+ +g+
  EEA18492.1 404 IFWLKGMAGTGKSTISRTVAESLNMEGK 431
                 78*********************99885 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   0.00023      0.16      18      44 ..     400     426 ..     385     504 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00023
                 SCSEEEEEEESTTSSHHHHHHHHCCSH CS
      NB-ARC  18 lqslvvalvGmgGvGKttlakqilnks 44 
                  ++ +  l Gm+G GK+t+++ + +++
  EEA18492.1 400 QGKSIFWLKGMAGTGKSTISRTVAESL 426
                 44568899*************999884 PP

>> PIF1  PIF1-like helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00036      0.25      11      51 ..     390     431 ..     382     435 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00036
                 HHH......HCTS-EE.EEESTTSSCHHHHHHHHHHCHCTCC CS
        PIF1  11 daiieavlnekgklfF.vtGsgGtgKtflwkallkklrsegk 51 
                 ++i e + n +gk++F ++G++GtgK+ + +++ ++l+ egk
  EEA18492.1 390 RQIREWAENAQGKSIFwLKGMAGTGKSTISRTVAESLNMEGK 431
                 6788888999998766389****************9998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1597 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       558  (0.0311228); expected 358.6 (0.02)
Passed bias filter:                      533  (0.0297284); expected 358.6 (0.02)
Passed Vit filter:                        80  (0.00446204); expected 17.9 (0.001)
Passed Fwd filter:                        26  (0.00145016); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              26  [number of targets reported over threshold]
# CPU time: 1.18u 0.38s 00:00:01.56 Elapsed: 00:00:00.65
# Mc/sec: 7355.82
//
Query:       EEA18493.1  [L=350]
Description: hypothetical protein PMAA_102690 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
      0.025   14.6   0.3      0.037   14.0   0.3    1.3  1  RXT2_N          RXT2-like, N-terminal
       0.18   12.0   2.5       0.48   10.7   2.5    1.7  1  DUF4611         Domain of unknown function (DUF4611)
       0.74    9.5   7.4        1.2    8.9   7.4    1.3  1  Cwf_Cwc_15      Cwf15/Cwc15 cell cycle control protein
        1.6    7.8  11.4        2.8    7.0  11.4    1.3  1  DUF2457         Protein of unknown function (DUF2457)
          2    8.9  15.0       0.17   12.3   9.9    1.8  2  CENP-B_dimeris  Centromere protein B dimerisation domain
        6.6    6.7   5.8         11    6.0   5.8    1.3  1  DUF2076         Uncharacterized protein conserved in bacteria


Domain annotation for each model (and alignments):
>> RXT2_N  RXT2-like, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.3   1.2e-05     0.037      61     139 ..      57     130 ..      10     145 .. 0.64

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1.2e-05
      RXT2_N  61 ekeeeeedeegdeededdddeeeaeaaeenpykkvrleelLaPltspsdlithpslsrty.kskaLteLalqlieliekE 139
                   ++++ d++++++d+d+dd+   ++++++ y+++   ++  Pl+s+  l + +  sr+  + + L++ ++ +   i++E
  EEA18493.1  57 AASRDKFDDDDSDDDNDNDDD---DDDNDDNYHDF---TIFRPLSSLDTLLQLDFTSRPVeTPSPLEKCSSPIALQICQE 130
                 334444444444444444442...22344555555...567888888888888888877733345666666666666666 PP

>> DUF4611  Domain of unknown function (DUF4611)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   2.5   0.00016      0.48      48      79 ..      53      84 ..      23      90 .. 0.73

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00016
     DUF4611 48 tlveqeaqddvaaagdeeeegededdeeeekn 79
                ++ve   +d+++++++++++++d+dd++++ n
  EEA18493.1 53 QVVEAASRDKFDDDDSDDDNDNDDDDDDNDDN 84
                56777778888777777777666666655554 PP

>> Cwf_Cwc_15  Cwf15/Cwc15 cell cycle control protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   7.4   0.00039       1.2     127     146 ..      62      81 ..      13      88 .. 0.65

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00039
                 -------------------- CS
  Cwf_Cwc_15 127 eesdddsdsdsdddddedet 146
                 + +dddsd+d+d+ddd+d++
  EEA18493.1  62 KFDDDDSDDDNDNDDDDDDN 81 
                 22222222222222222222 PP

>> DUF2457  Protein of unknown function (DUF2457)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0  11.4   0.00093       2.8      63      86 ..      61      84 ..      46      95 .. 0.45

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.00093
     DUF2457 63 deeddddddddedddedddeeded 86
                d+ dddd ddd+d+d+ddd++d++
  EEA18493.1 61 DKFDDDDSDDDNDNDDDDDDNDDN 84
                222222222222222222222222 PP

>> CENP-B_dimeris  Centromere protein B dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   9.9   5.5e-05      0.17       2      36 ..      51      85 ..      50     108 .. 0.65
   2 ?   -2.2   0.2       1.8   5.4e+03      33      40 ..     224     231 ..     223     248 .. 0.60

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 5.5e-05
  CENP-B_dimeris  2 alqlleagedsesesdeeeeeeeedeededeedde 36
                    a q++ea    + + d+ ++++++d++d+d++d+ 
      EEA18493.1 51 AAQVVEAASRDKFDDDDSDDDNDNDDDDDDNDDNY 85
                    56666666665555555555555555555555443 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.8
  CENP-B_dimeris  33 eddeddde 40 
                     edd ddd 
      EEA18493.1 224 EDDHDDDG 231
                     34445544 PP

>> DUF2076  Uncharacterized protein conserved in bacteria (DUF2076)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   5.8    0.0037        11     221     257 ..      58      83 ..      37      91 .. 0.61

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.0037
     DUF2076 221 asadsfadsdsssdnnadaasdddsdddssddgggDD 257
                 as+           +++d++++dd++d+++dd+++DD
  EEA18493.1  58 ASR-----------DKFDDDDSDDDNDNDDDDDDNDD 83 
                 333...........34444444444444444555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (350 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       517  (0.028836); expected 358.6 (0.02)
Passed bias filter:                      395  (0.0220313); expected 358.6 (0.02)
Passed Vit filter:                        67  (0.00373696); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 2416.39
//
Query:       EEA18494.1  [L=344]
Description: hypothetical protein PMAA_102690 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
      0.027   14.5   0.4      0.042   13.9   0.4    1.3  1  RXT2_N          RXT2-like, N-terminal
       0.18   12.0   2.5       0.47   10.7   2.5    1.7  1  DUF4611         Domain of unknown function (DUF4611)
        1.5    7.8  11.3        2.6    7.1  11.3    1.3  1  DUF2457         Protein of unknown function (DUF2457)
        1.9    8.9  15.0       0.16   12.4   9.9    1.8  2  CENP-B_dimeris  Centromere protein B dimerisation domain
        2.3    7.9   9.0        3.8    7.2   9.0    1.3  1  Cwf_Cwc_15      Cwf15/Cwc15 cell cycle control protein
        9.9    5.4  12.4         17    4.7  12.4    1.2  1  NOA36           NOA36 protein


Domain annotation for each model (and alignments):
>> RXT2_N  RXT2-like, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.4   1.4e-05     0.042      62     139 ..      52     124 ..       7     139 .. 0.65

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.4e-05
      RXT2_N  62 keeeeedeegdeededdddeeeaeaaeenpykkvrleelLaPltspsdlithpslsrty.kskaLteLalqlieliekE 139
                  ++++ d++++++d+d+dd+   ++++++ y+++   ++  Pl+s+  l + +  sr+  + + L++ ++ +   i++E
  EEA18494.1  52 ASRDKFDDDDSDDDNDNDDD---DDDNDDNYHDF---TIFRPLSSLDTLLQLDFTSRPVeTPSPLEKCSSPIALQICQE 124
                 34444444444444444442...22344555555...567888888888888888877733345666666666666666 PP

>> DUF4611  Domain of unknown function (DUF4611)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   2.5   0.00016      0.47      48      79 ..      47      78 ..      17      84 .. 0.73

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00016
     DUF4611 48 tlveqeaqddvaaagdeeeegededdeeeekn 79
                ++ve   +d+++++++++++++d+dd++++ n
  EEA18494.1 47 QVVEAASRDKFDDDDSDDDNDNDDDDDDNDDN 78
                56777778888777777777666666655554 PP

>> DUF2457  Protein of unknown function (DUF2457)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1  11.3   0.00087       2.6      63      86 ..      55      78 ..      42      89 .. 0.43

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.00087
     DUF2457 63 deeddddddddedddedddeeded 86
                d+ dddd ddd+d+d+ddd++d++
  EEA18494.1 55 DKFDDDDSDDDNDNDDDDDDNDDN 78
                222222222222222222222222 PP

>> CENP-B_dimeris  Centromere protein B dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   9.9   5.4e-05      0.16       2      36 ..      45      79 ..      44     102 .. 0.65
   2 ?   -2.1   0.2       1.8   5.3e+03      33      40 ..     218     225 ..     217     242 .. 0.60

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 5.4e-05
  CENP-B_dimeris  2 alqlleagedsesesdeeeeeeeedeededeedde 36
                    a q++ea    + + d+ ++++++d++d+d++d+ 
      EEA18494.1 45 AAQVVEAASRDKFDDDDSDDDNDNDDDDDDNDDNY 79
                    56666666665555555555555555555555443 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.8
  CENP-B_dimeris  33 eddeddde 40 
                     edd ddd 
      EEA18494.1 218 EDDHDDDG 225
                     34445544 PP

>> Cwf_Cwc_15  Cwf15/Cwc15 cell cycle control protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   9.0    0.0013       3.8     127     146 ..      56      75 ..      31      82 .. 0.53

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0013
                 -------------------- CS
  Cwf_Cwc_15 127 eesdddsdsdsdddddedet 146
                 + +dddsd+d+d+ddd+d++
  EEA18494.1  56 KFDDDDSDDDNDNDDDDDDN 75 
                 22222222222222222222 PP

>> NOA36  NOA36 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7  12.4    0.0055        17     269     293 ..      54      78 ..      38      83 .. 0.39

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.0055
       NOA36 269 eddegdedddddddeedddeeedde 293
                 +d+  d+d ddd+d++ddd+++dd+
  EEA18494.1  54 RDKFDDDDSDDDNDNDDDDDDNDDN 78 
                 2222222222222222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (344 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       497  (0.0277205); expected 358.6 (0.02)
Passed bias filter:                      382  (0.0213063); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.45
# Mc/sec: 2319.69
//
Query:       EEA18495.1  [L=298]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0079   16.4   0.0      0.021   15.1   0.0    1.7  1  BTB       BTB/POZ domain


Domain annotation for each model (and alignments):
>> BTB  BTB/POZ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   1.1e-06     0.021      19      76 ..      65     122 ..      50     133 .. 0.86

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 1.1e-06
                 T.TEEEEE-HHHHHHH-HHHHHHHTSTTTTTCCCEEEEETTSGHHHHHHHHHHHHHSEE CS
         BTB  19 d.gkefkahkavLaarSpyFkalftskeieessvseielddvepeafealLefiYtgel 76 
                   +++f+ hka L + S+   + f++  ++e+++ ++  ++ +  ++ +++e++Y+g  
  EEA18495.1  65 SsTRTFRIHKALLLSKSKAIFSAFEHR-FQEKENGVYIFKETTEGTVTRFIEWAYRGDY 122
                 45799*********************9.88888778889999999**********9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (298 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       440  (0.0245412); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                         9  (0.00050198); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2216.93
//
Query:       EEA18496.1  [L=1012]
Description: RNA interference and gene silencing protein (Qde2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.7e-72  241.9   0.0    1.4e-71  241.3   0.0    1.3  1  Piwi             Piwi domain
    6.4e-16   59.2   0.1    1.4e-15   58.1   0.1    1.6  1  ArgoN            N-terminal domain of argonaute
    8.9e-16   57.3   0.3      3e-15   55.6   0.3    1.9  1  ArgoL1           Argonaute linker 1 domain
    7.5e-11   42.2   0.0    2.5e-09   37.3   0.0    2.9  2  ArgoL2           Argonaute linker 2 domain
    1.6e-08   34.4   0.0    3.5e-08   33.3   0.0    1.5  1  PAZ              PAZ domain


Domain annotation for each model (and alignments):
>> Piwi  Piwi domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  241.3   0.0   3.8e-75   1.4e-71       2     300 ..     645     966 ..     644     968 .. 0.91

  Alignments for each domain:
  == domain 1  score: 241.3 bits;  conditional E-value: 3.8e-75
                 EEEEECSSGHHCHHHHHHHHHHTCCCCEEEEEHHHHCTCCHHHHHHHHHHHHHHHHTT-BS-EEESSSTTSSE......EEEEEEEEEECCC.SCCCEE CS
        Piwi   2 ilvilpekkkdkyheikkyletdlgiisqcillktilkrqlkkqtltnvllkinvKlGgknvliveikleldv..sptliiGidishgtagt.vdnpsv 97 
                 + vilp+ +++ y+ ik  +++d+gi+++c  ++++ k    +q+++n++lk+n+KlGg+n  + + +l + v  ++t+++Gid++h++ g  ++ ps+
  EEA18496.1 645 LYVILPQANTTLYKRIKTLTDKDFGIHTICSVASKLAKERGRDQYMANIALKFNLKLGGINQIVENRNLGI-VdqNKTMVVGIDVTHPSPGSsSNAPSI 742
                 679***********************************9889*******************9999999987.559****************98899*** PP

                 EEEEEEEETSSEEEEEEEEESSCCCCHHHHHHHHHHHHHHHHHHTTTT.-TTSEEEEEESS....S..S-HHHHHHHHHHHHHHHHHCTT.....TEEE CS
        Piwi  98 aavvasldkensrylaevstqassqelleklkeiikellrefkksskk.kkperiivyRdGvseGqfkqvlnsEvkelkealkklkeqyq.....pklt 190
                  a+vas+d    ++ a+ + q ++qe +++l+e++k  l  +k+  k+  +pe+i++yRdGvseGq+  vl  E+++l++a++++ +        p++t
  EEA18496.1 743 SAMVASIDRSLGQWPATLRIQRARQENVDDLTEMFKSRLTLWKTRGKHtALPENILIYRDGVSEGQYDMVLSRELPQLRRACEEVYPTADtklglPRFT 841
                 ********9999******************************987654159********************************8887776667789*** PP

                 EEEEECSCS--EEESESTC..CCEETTTCEEETTEEEEEEEECCEEECCCCEEEEEEEEEEEEEEES....S-CCHHHHH..............HHHHC CS
        Piwi 191 vivvqkrhhtrfFasdkae..ksqnippGtvvdkkitlpeekdfylcshaglqgtvkPtkytvlvdea..klsadelqsl..............tyklc 271
                  i+  krh+trf++ ++++  +s n +pGtvvd  +t++ + df+l +ha lqgt++P++y +++de+  ++ a +   +              t+++c
  EEA18496.1 842 IIICGKRHKTRFYPTTEEDcdRSGNTKPGTVVDRGVTEARNWDFFLQAHAALQGTARPCHYYIVHDEIfrQVYAKS---IpapfqniadivedlTHNMC 937
                 **************9999999**********************************************633233332...233344447778888***** PP

                 TGGTTTTSS-SS-HHHHHHHHHHHHHHTC CS
        Piwi 272 hmyqrstrsvsiPapvyyAhklAkrvrnn 300
                 +++ r+t++vs+ +p+yyA+++ +r+r++
  EEA18496.1 938 YLFGRATKAVSLCPPAYYADLACERARCY 966
                 *************************9986 PP

>> ArgoN  N-terminal domain of argonaute
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.1   0.1   3.9e-19   1.4e-15       1     138 []     105     242 ..     105     242 .. 0.74

  Alignments for each domain:
  == domain 1  score: 58.1 bits;  conditional E-value: 3.9e-19
       ArgoN   1 rpiklraNyFkvtslpdktlyhYdveit.kkakrvglrriiellleeykkselagkkpayDgrknlysakkLp.kefe.dl..paaeesakkepsekrr 94 
                 ++++l+aNy ++  ++d  l++Yd +i+ + a r +  r+++lll+  ++   ++ ++a+D+r++l+s++k+p  e   ++     +e+++     +  
  EEA18496.1 105 TKVELTANYVELLPPSDLILHRYDIQISpEVAGRKR-SRVVQLLLRS-AEVASHRDEIATDFRSTLISKTKFPrDETIiEIryA--SEGED-----EPM 194
                 5899*********777779*****999954444545.89******43.223334677888************874444555422..33333.....334 PP

       ArgoN  95 rksrtfkvtikfaksinlqsLleylr....gkq.deasleaiqaLdivl 138
                 +++ t++v++ ++k++ + +L +y++    + q    ++e+ qaL+i+l
  EEA18496.1 195 ARATTYRVRVLYTKTLCILELINYINstnlD-QsFGDKQELTQALNIFL 242
                 5677**********9**********634432.23556777*******87 PP

>> ArgoL1  Argonaute linker 1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.6   0.3   8.3e-19     3e-15       4      52 .]     258     305 ..     256     305 .. 0.91

  Alignments for each domain:
  == domain 1  score: 55.6 bits;  conditional E-value: 8.3e-19
      ArgoL1   4 rsFfsppskqrvdLggggleawrGfyqSvRptqggLllNvDvsntaFyk 52 
                 + F  +++  r dL g+gle++rGf++SvR +++++l+N++vs++aFy+
  EEA18496.1 258 KTFSLNQNAVRGDL-GSGLEVIRGFFSSVRMATCRILVNINVSHGAFYQ 305
                 567777778899**.77*******************************6 PP

>> ArgoL2  Argonaute linker 2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.11   4.1e+02      32      45 ..     435     448 ..     420     450 .. 0.85
   2 !   37.3   0.0     7e-13   2.5e-09       1      47 []     497     546 ..     497     546 .. 0.93

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.11
      ArgoL2  32 mttVpGRvLppPtl 45 
                 + t+ GR+L+ P+l
  EEA18496.1 435 FKTTYGRILQHPEL 448
                 56889*******97 PP

  == domain 2  score: 37.3 bits;  conditional E-value: 7e-13
      ArgoL2   1 eRkksIle.gvkvlgydd.dpyl.rafGisidpqmttVpGRvLppPtlkY 47 
                 e++++I++ gv+++g+d+ ++ l r+fG++i + ++++pGRvL  P++ Y
  EEA18496.1 497 ENAAAIVAeGVQTVGLDEnSNALmRSFGLRIAQGLIKIPGRVLVGPKVIY 546
                 89**************88457779***********************988 PP

>> PAZ  PAZ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.3   0.0   9.7e-12   3.5e-08      61     136 ..     425     487 ..     409     488 .. 0.86

  Alignments for each domain:
  == domain 1  score: 33.3 bits;  conditional E-value: 9.7e-12
                 TTCT..CECCHHHHCCT---ST-TT--EEEEEES-SS----EEEEE-CCCCEEESSBCCCCCTCCCHHHHCCCH.. CS
         PAZ  61 kdkeneitfaeYfkkkYnieikdqdqplldvdkktesehssqkqiLvpElcdihpisasqrykkkllpsilqrlnl 136
                 +  +++i++ ++fk+ Y+  +++ ++pll++++      ++++ +L++E+c +    ++q +k kl  +  q+ ++
  EEA18496.1 425 S--GKYISVFDFFKTTYGRILQHPELPLLNCGS------RENPMYLPVEVCIV---LPGQPSKSKL--DGTQTQQM 487
                 2..379***************************......89************...9999999998..77777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1012 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       438  (0.0244297); expected 358.6 (0.02)
Passed bias filter:                      405  (0.0225891); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.73u 0.32s 00:00:01.05 Elapsed: 00:00:00.50
# Mc/sec: 6131.05
//
Query:       EEA18497.1  [L=316]
Description: hypothetical protein PMAA_102720 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
  ------ inclusion threshold ------
       0.14   12.3   1.7         10    6.3   0.1    2.9  3  Prefoldin_3  Prefoldin subunit
        2.2    8.8  10.0       0.15   12.5   1.4    2.4  2  TBCC_N       Tubulin-specific chaperone C N-terminal domain


Domain annotation for each model (and alignments):
>> Prefoldin_3  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.0    0.0054        48      31      56 ..      68      93 ..      57     102 .. 0.87
   2 ?   -2.0   0.1      0.41   3.7e+03       5      23 ..     166     184 ..     163     212 .. 0.58
   3 ?    6.3   0.1    0.0011        10      66      85 ..     282     301 ..     254     315 .. 0.74

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.0054
  Prefoldin_3 31 teedllriardfegslvtekEveeil 56
                 + ++l++i+ +  g+ ++e+Ev +++
   EEA18497.1 68 EASQLRNISSNARGRTLNEDEVLVLF 93
                 5689******************9887 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.41
  Prefoldin_3   5 yklreweaeydglkeeisa 23 
                  +++ e  +ey++ ++e  +
   EEA18497.1 166 DEWIEFLQEYSEEEKEDLT 184
                  5566666666655444332 PP

  == domain 3  score: 6.3 bits;  conditional E-value: 0.0011
  Prefoldin_3  66 kqQvvdlisrRiDYVkqnik 85 
                    Q v+ is+R+D  ++ni+
   EEA18497.1 282 LAQQVKNISKRVDTLEENIN 301
                  3577889***********97 PP

>> TBCC_N  Tubulin-specific chaperone C N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   1.8     0.081   7.2e+02       2      66 ..     134     205 ..     133     214 .. 0.59
   2 ?   12.5   1.4   1.7e-05      0.15      13      79 ..     234     300 ..     226     315 .. 0.81

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.081
      TBCC_N   2 rLekReqerqeqlekrkeereseaveeekvds.....FlkaFteekaa..ieellesveesadksklkqkld 66 
                 ++e+R ++r+++ +k +  re ea++   v+      Fl++ +ee+++    + l+++e++a++ +++++l 
  EEA18497.1 134 KIEARVRAREAYTQKYETGRETEASTPLDVAIdewieFLQEYSEEEKEdlTVTCLDTMEKAAKRRAQSSQLT 205
                 567788888888888888888777664444445566688888766544224556666664444444444443 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 1.7e-05
      TBCC_N  13 qlekrkeereseaveeekvds.FlkaFteekaaieellesveesadksklkqkldeitaeiqeLqkll 79 
                 +++ +k++r ++a ++e   +  ++++++ ++ i++l++ ++ ++d+++l+q++++i++++++L++ +
  EEA18497.1 234 ASRGKKQKRGQAAFSFEDFMTlHQENLKQDRRLIKSLITPSS-NKDHDALAQQVKNISKRVDTLEENI 300
                 45556777777777755544416789****************.*********************9855 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (316 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1581  (0.0881812); expected 358.6 (0.02)
Passed bias filter:                      594  (0.0331307); expected 358.6 (0.02)
Passed Vit filter:                        74  (0.00412739); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.47
# Mc/sec: 2035.81
//
Query:       EEA18498.1  [L=513]
Description: IBR finger domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.8e-16   60.1  37.5    3.8e-09   36.6   8.6    3.6  3  IBR       IBR domain, a half RING-finger domain
  ------ inclusion threshold ------
       0.51   10.5   0.1       0.51   10.5   0.1    2.7  3  CCDC50_N  Coiled-coil domain-containing protein 50  N-terminu


Domain annotation for each model (and alignments):
>> IBR  IBR domain, a half RING-finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.3   0.8   0.00063       5.7      25      54 ..     170     198 ..     144     205 .. 0.82
   2 !   36.6   8.6   4.3e-13   3.8e-09       4      59 ..     235     291 ..     232     293 .. 0.84
   3 !   26.5  13.5   6.1e-10   5.5e-06      14      62 .]     307     351 ..     296     351 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.00063
         IBR  25 dCeaiieksegcksvtCskCgfefCfnCkk 54 
                 +C a +e++e  + v+ + C++e+C  C++
  EEA18498.1 170 QCVACVEEKEFVDVVRVP-CQHEYCRICLE 198
                 455555666666668999.*********87 PP

  == domain 2  score: 36.6 bits;  conditional E-value: 4.3e-13
         IBR   4 eklklkksles.dpnlkwCprpdCeaiiekseg.cksvtCskCgfefCfnCkkewHeg 59 
                 +++ +k ++e  +pn+++C +p+C+a+ie+++   + +tC+ C++ +C+nCk+ +H g
  EEA18498.1 235 KQFEKK-KIEFeTPNRTYCYSPECSAFIEPTHIhGEVATCPICEHTTCINCKQRAHTG 291
                 444444.58888********************9544588*****************86 PP

  == domain 3  score: 26.5 bits;  conditional E-value: 6.1e-10
         IBR  14 sdpnlkwCprpdCeaiieksegcksvtCskCgfefCfnCkkewHeglsC 62 
                 +++ ++ C    C +i+e + gc+++tC+ Cg +fC+nC+++w + ++C
  EEA18498.1 307 QENGWQRCY--SCWRIVELNYGCNHMTCP-CGAQFCYNCGEAWKN-CAC 351
                 23449***9..9*****************.*************85.555 PP

>> CCDC50_N  Coiled-coil domain-containing protein 50  N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.1   5.7e-05      0.51      93     124 ..      27      58 ..       8      60 .. 0.74
   2 ?   -1.0   0.2      0.21   1.9e+03      89     111 ..      75      97 ..      60     101 .. 0.62
   3 ?   -1.4   0.1      0.28   2.5e+03      51      62 ..     424     435 ..     396     448 .. 0.64

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 5.7e-05
    CCDC50_N  93 llreaeerrrreeeDeeiAkrLqeeeeeeekr 124
                 l +   + ++re  Dee+A +Lq+ee e+  r
  EEA18498.1  27 LYSDTSKGKSREPTDEELAFHLQNEELESISR 58 
                 3337889999***************9988766 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.21
    CCDC50_N  89 iqeellreaeerrrreeeDeeiA 111
                    ++l e +e+++++ +D  iA
  EEA18498.1  75 ADGHILAENQEEEEKASKDRLIA 97 
                 33444556677777777777776 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.28
    CCDC50_N  51 kDlrvAkrlqee 62 
                 +D+ vA+ +qe 
  EEA18498.1 424 RDILVARTIQEL 435
                 345555555542 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (513 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       916  (0.0510904); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 3373.11
//
Query:       EEA18499.1  [L=485]
Description: IBR finger domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      3e-14   53.0  56.3    3.6e-09   36.7   8.6    4.5  4  IBR       IBR domain, a half RING-finger domain
  ------ inclusion threshold ------
       0.48   10.6   0.1       0.48   10.6   0.1    2.7  3  CCDC50_N  Coiled-coil domain-containing protein 50  N-terminu


Domain annotation for each model (and alignments):
>> IBR  IBR domain, a half RING-finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.4   0.8   0.00059       5.3      25      54 ..     170     198 ..     144     205 .. 0.82
   2 !   36.7   8.6     4e-13   3.6e-09       4      59 ..     235     291 ..     232     293 .. 0.84
   3 !   26.6  13.5   5.6e-10   5.1e-06      14      62 .]     307     351 ..     296     351 .. 0.80
   4 ?   -1.0  10.8      0.24   2.1e+03      38      54 ..     457     482 ..     430     484 .. 0.67

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.00059
         IBR  25 dCeaiieksegcksvtCskCgfefCfnCkk 54 
                 +C a +e++e  + v+ + C++e+C  C++
  EEA18499.1 170 QCVACVEEKEFVDVVRVP-CQHEYCRICLE 198
                 455555666666668999.*********87 PP

  == domain 2  score: 36.7 bits;  conditional E-value: 4e-13
         IBR   4 eklklkksles.dpnlkwCprpdCeaiiekseg.cksvtCskCgfefCfnCkkewHeg 59 
                 +++ +k ++e  +pn+++C +p+C+a+ie+++   + +tC+ C++ +C+nCk+ +H g
  EEA18499.1 235 KQFEKK-KIEFeTPNRTYCYSPECSAFIEPTHIhGEVATCPICEHTTCINCKQRAHTG 291
                 444444.58888********************9544588*****************86 PP

  == domain 3  score: 26.6 bits;  conditional E-value: 5.6e-10
         IBR  14 sdpnlkwCprpdCeaiieksegcksvtCskCgfefCfnCkkewHeglsC 62 
                 +++ ++ C    C +i+e + gc+++tC+ Cg +fC+nC+++w + ++C
  EEA18499.1 307 QENGWQRCY--SCWRIVELNYGCNHMTCP-CGAQFCYNCGEAWKN-CAC 351
                 23449***9..9*****************.*************85.555 PP

  == domain 4  score: -1.0 bits;  conditional E-value: 0.24
         IBR  38 s.........vtCskCgfefCfnCkk 54 
                 +          +C++C+ + C +C++
  EEA18499.1 457 EcshvlpkyiFECRQCRLRACNRCRR 482
                 134455566578************96 PP

>> CCDC50_N  Coiled-coil domain-containing protein 50  N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.1   5.3e-05      0.48      93     124 ..      27      58 ..       8      60 .. 0.74
   2 ?   -0.9   0.2      0.19   1.7e+03      89     111 ..      75      97 ..      59     101 .. 0.62
   3 ?   -1.2   0.1      0.23   2.1e+03      51      62 ..     424     435 ..     396     454 .. 0.67

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 5.3e-05
    CCDC50_N  93 llreaeerrrreeeDeeiAkrLqeeeeeeekr 124
                 l +   + ++re  Dee+A +Lq+ee e+  r
  EEA18499.1  27 LYSDTSKGKSREPTDEELAFHLQNEELESISR 58 
                 3337889999***************9988766 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.19
    CCDC50_N  89 iqeellreaeerrrreeeDeeiA 111
                    ++l e +e+++++ +D  iA
  EEA18499.1  75 ADGHILAENQEEEEKASKDRLIA 97 
                 33444556677777777777776 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 0.23
    CCDC50_N  51 kDlrvAkrlqee 62 
                 +D+ vA+ +qe 
  EEA18499.1 424 RDILVARTIQEL 435
                 355555555543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (485 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       955  (0.0532657); expected 358.6 (0.02)
Passed bias filter:                      352  (0.019633); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.49
# Mc/sec: 2970.91
//
Query:       EEA18500.1  [L=179]
Description: hypothetical protein PMAA_102740 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (179 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       502  (0.0279993); expected 358.6 (0.02)
Passed bias filter:                      360  (0.0200792); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.24s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 1311.30
//
Query:       EEA18501.1  [L=100]
Description: hypothetical protein PMAA_102750 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        6.4    7.1  11.9       0.17   12.2   1.8    2.2  2  TadE      TadE-like protein


Domain annotation for each model (and alignments):
>> TadE  TadE-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   1.8   9.2e-06      0.17       7      35 ..      51      76 ..      43      80 .. 0.81
   2 ?    0.1   2.8     0.055   9.8e+02      13      25 ..      87      99 ..      87     100 .] 0.81

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 9.2e-06
        TadE  7 FALvlPlllllllgiiefgrylyarqtln 35
                FAL++    l+llg++ + +y+++r++++
  EEA18501.1 51 FALLII---LVLLGVFAYEMYIQYRHAVT 76
                455555...5666**************98 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.055
        TadE 13 lllllllgiiefg 25
                l++ll+ ++++f+
  EEA18501.1 87 LIFLLIGFVFQFS 99
                578899999**98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (100 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1025  (0.0571699); expected 358.6 (0.02)
Passed bias filter:                      503  (0.0280551); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.28s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 701.31
//
Query:       EEA18502.1  [L=212]
Description: hypothetical protein PMAA_102760 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (212 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       463  (0.0258241); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.41u 0.27s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 1520.03
//
Query:       EEA18503.1  [L=136]
Description: hypothetical protein PMAA_102770 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (136 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       296  (0.0165096); expected 358.6 (0.02)
Passed bias filter:                      239  (0.0133304); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.45
# Mc/sec: 901.17
//
Query:       EEA18504.1  [L=285]
Description: hypothetical protein PMAA_102780 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.5e-06   26.4   6.0    6.8e-06   25.8   6.0    1.3  1  zf-C3HC4_3       Zinc finger, C3HC4 type (RING finger)
    1.3e-05   25.1   5.3      3e-05   24.0   5.3    1.6  1  zf-RING_UBOX     RING-type zinc-finger
    0.00013   22.6  16.7     0.0002   21.9  16.7    1.3  1  APG6_N           Apg6 coiled-coil region
     0.0002   20.7   7.3    0.00026   20.3   7.3    1.3  1  Tho2             Transcription factor/nuclear export subunit 
    0.00039   20.1   8.4    0.00047   19.8   8.4    1.1  1  Exonuc_VII_L     Exonuclease VII, large subunit
    0.00041   20.2   5.1     0.0008   19.2   5.1    1.5  1  zf-C3HC4         Zinc finger, C3HC4 type (RING finger)
     0.0015   18.3   3.2     0.0032   17.3   3.2    1.6  1  zf-C3HC4_2       Zinc finger, C3HC4 type (RING finger)
     0.0017   18.3   6.6     0.0029   17.5   6.6    1.4  1  zf-RING_5        zinc-RING finger domain
     0.0018   17.2  18.3     0.0028   16.6  18.3    1.2  1  Spc7             Spc7 kinetochore protein
     0.0027   17.6  18.1     0.0038   17.1  18.1    1.1  1  KASH_CCD         Coiled-coil region of CCDC155 or KASH
      0.004   17.0   3.4      0.012   15.5   3.5    1.8  2  Prok-RING_4      Prokaryotic RING finger family 4
     0.0047   17.2   5.8     0.0081   16.5   5.8    1.4  1  zf-RING_2        Ring finger domain
     0.0073   16.1  16.1      0.011   15.6  16.1    1.2  1  ERM              Ezrin/radixin/moesin family
     0.0078   16.3   5.0      0.033   14.3   5.3    2.0  1  zf-C3HC4_4       zinc finger of C3HC4-type, RING
     0.0092   15.4  21.2      0.013   14.9  21.2    1.2  1  GAS              Growth-arrest specific micro-tubule binding
  ------ inclusion threshold ------
      0.011   15.6   4.4      0.019   14.8   4.4    1.4  1  zf-C3HC4_5       Zinc finger, C3HC4 type (RING finger)
      0.015   15.2  15.5      0.023   14.6  15.5    1.4  1  Ax_dynein_light  Axonemal dynein light chain
      0.017   14.4  17.1      0.024   14.0  17.1    1.2  1  DUF3450          Protein of unknown function (DUF3450)
      0.021   14.6  11.0      0.029   14.1  11.0    1.1  1  DUF1351          Protein of unknown function (DUF1351)
      0.025   14.7  20.5      0.034   14.3  20.5    1.2  1  UPF0242          Uncharacterised protein family (UPF0242) N-t
      0.032   14.1   2.3       0.06   13.2   2.3    1.4  1  zf-RING_6        zf-RING of BARD1-type protein
      0.041   13.3  17.2      0.058   12.9  17.2    1.1  1  Golgin_A5        Golgin subfamily A member 5
      0.054   11.0  15.1      0.068   10.7  15.1    1.0  1  DUF3584          Protein of unknown function (DUF3584)
      0.063   13.8  12.8      0.094   13.2  12.8    1.3  1  AAA_23           AAA domain
       0.08   13.1   8.6       0.24   11.6   0.1    2.2  2  COG5             Golgi transport complex subunit 5
      0.094   12.8  20.3       0.14   12.3  20.3    1.2  1  ADIP             Afadin- and alpha -actinin-Binding
        0.1   10.5   8.8       0.13   10.2   8.8    1.0  1  V_ATPase_I       V-type ATPase 116kDa subunit family
       0.13   12.5  11.6       0.23   11.7  11.6    1.3  1  zf-C4H2          Zinc finger-containing protein
       0.14   10.7  12.4       0.18   10.4  12.4    1.1  1  FapA             Flagellar Assembly Protein A
       0.14   12.3  12.8       0.28   11.4  12.8    1.5  1  JIP_LZII         JNK-interacting protein  leucine zipper II
       0.18   11.0   3.5       0.24   10.6   3.5    1.1  1  FTO_NTD          FTO catalytic domain
       0.25   11.5  18.2       0.49   10.6  18.2    1.5  1  Jnk-SapK_ap_N    JNK_SAPK-associated protein-1
       0.25    9.2   5.2       0.32    8.9   5.2    1.1  1  Prominin         Prominin
       0.38    9.2  11.7       0.45    9.0  11.7    1.0  1  Macoilin         Macoilin family
       0.49    9.2   9.7       0.69    8.7   9.7    1.2  1  5_nucleotid      5' nucleotidase family
       0.67   10.2  27.0        1.1    9.6   3.9    2.9  3  HALZ             Homeobox associated leucine zipper
          1    9.8  14.4        1.7    9.1  14.4    1.3  1  CENP-H           Centromere protein H (CENP-H)
        1.1    7.9  16.1        1.6    7.4   5.9    2.8  3  Dor1             Dor1-like family
        1.3    8.2  16.0        1.8    7.8  16.0    1.1  1  HemX             HemX, putative uroporphyrinogen-III C-methyl
        1.4    7.8   9.9        1.8    7.4   9.9    1.1  1  FemAB            FemAB family
        1.4    8.5  19.1       0.46   10.1  11.5    1.9  2  DUF4795          Domain of unknown function (DUF4795)
        1.7    7.8  13.1        2.3    7.4  13.1    1.2  1  TMPIT            TMPIT-like protein
        1.8    8.6  11.6        3.7    7.6  11.6    1.5  1  DUF1664          Protein of unknown function (DUF1664)
          2    8.0  17.9       0.41   10.2   7.0    2.5  2  NRBF2            Nuclear receptor-binding factor 2, autophagy
        2.2    8.3  17.6       0.19   11.8   6.1    2.2  2  DivIVA           DivIVA protein
        2.3    7.9  12.1          3    7.5  12.1    1.1  1  AAA_11           AAA domain
        2.4    6.8   3.9        2.6    6.7   3.9    1.1  1  Presenilin       Presenilin
        3.2    7.1  22.9        4.5    6.6  22.9    1.1  1  DUF3552          Domain of unknown function (DUF3552)
        3.8    8.2  17.6          7    7.4   5.0    2.2  2  YabA             Initiation control protein YabA
        5.3    7.0  27.4        4.1    7.4  11.3    2.3  2  Prefoldin_2      Prefoldin subunit
        5.5    6.1  10.1        9.4    5.4  10.1    1.5  1  DUF1943          Domain of unknown function (DUF1943)
        6.3    7.1  19.5         10    6.4  19.5    1.2  1  Seryl_tRNA_N     Seryl-tRNA synthetase N-terminal domain
        6.4    7.3  20.7         20    5.7  10.1    2.8  2  UPF0449          Uncharacterised protein family UPF0449
        6.7    6.7   5.3        8.8    6.3   5.3    1.2  1  Neur_chan_memb   Neurotransmitter-gated ion-channel transmemb
        7.1    5.9  11.9        9.9    5.4  11.9    1.1  1  DUF4407          Domain of unknown function (DUF4407)
        7.9    5.3   6.3        9.5    5.0   6.3    1.1  1  LMBR1            LMBR1-like membrane protein
          8    6.0   8.3         11    5.5   8.3    1.1  1  SseC             Secretion system effector C (SseC) like fami
        8.4    6.0  24.2         13    5.3  24.0    1.3  1  DUF2968          Protein of unknown function (DUF2968)


Domain annotation for each model (and alignments):
>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   6.0   2.2e-08   6.8e-06       3      48 ..     222     273 ..     220     275 .. 0.93

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 2.2e-08
                 SB-TTTSSS.BS-EEETTEEEEEE-HHHHHHHHH....TT-B-TT..T--B-- CS
  zf-C3HC4_3   3 eeCviCler.prnvvllpCgHlvlCeeCaekllk....rkkkCpi..Crrpie 48 
                  +C +C+++ ++++ +l CgH+ lC++C+e++++        Cp+  C++pi+
  EEA18504.1 222 LKCALCHRTfNESWKFLGCGHT-LCQTCLEDIESkglgFGYPCPYpeCKKPIR 273
                 68******97888*********.*********999**99*****999***996 PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.0   5.3   9.5e-08     3e-05       1      39 []     224     264 ..     224     264 .. 0.90

  Alignments for each domain:
  == domain 1  score: 24.0 bits;  conditional E-value: 9.5e-08
  zf-RING_UBOX   1 CpIClelftdP.lvlpCGHtFCreClw.elskslegafkCP 39 
                   C  C  +f++  ++l+CGHt+C+ Cl+  +sk+l+  + CP
    EEA18504.1 224 CALCHRTFNESwKFLGCGHTLCQTCLEdIESKGLGFGYPCP 264
                   99******9887678***********778899999999998 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.9  16.7   6.4e-07    0.0002      63     132 ..     143     212 ..     102     220 .. 0.54

  Alignments for each domain:
  == domain 1  score: 21.9 bits;  conditional E-value: 6.4e-07
      APG6_N  63 eeelleeLkelekereeleaelaaleeelealeeeeerfwreynelqlelleleeeldsleaqyehaqnq 132
                  +e  e  ++le+e+++l++e ++l++ +e+l++++e+  ++  +l+ ++++l++++++l+ q+++ ++q
  EEA18504.1 143 VKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQ 212
                 3333444455555555555555555555555555555555555555555555555555555555555554 PP

>> Tho2  Transcription factor/nuclear export subunit protein 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   7.3   8.3e-07   0.00026      20      93 ..     146     219 ..     102     249 .. 0.92

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 8.3e-07
        Tho2  20 iyvpkeqYekeieklkseieelakdrsderaaakkkkkekkrlkeliekLeeEkkeqiehvekvkkrLkeekks 93 
                 +  p e+ e+e ++l++e+++l+kd+++ ++++++ +k+k++l++++e+L+++kk+ + + +  ++++ e+k +
  EEA18504.1 146 VTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDEQKRR 219
                 666888889*************9999888*****************************************9987 PP

>> Exonuc_VII_L  Exonuclease VII, large subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   8.4   1.5e-06   0.00047     162     260 ..     130     217 ..      76     244 .. 0.59

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 1.5e-06
  Exonuc_VII_L 162 rlleekkqrleklasrlkspeellerkrqrldeleerleralkkqlkkkrerleelkerlkekleekkerlkklkerle.lleekkerleeleekle 257
                   +++ + ++r++++ +++++p e le++++rl++ +++l++  k+ql+k +e+l++ ke+l+    ++ke+l+k k++l+ +       ++ l ++++
    EEA18504.1 130 SNVVDFQSRIKRFVKEVTEPYEALEQENKRLNQESHQLKK-DKEQLQKDKEQLQKDKEQLR----KNKEQLQKDKKQLQlQ-------IQYLRRQID 214
                   2334455566666666677777777777777777777777.66677777777777775553....3333333332222221.......222222222 PP

  Exonuc_VII_L 258 als 260
                     +
    EEA18504.1 215 EQK 217
                   222 PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   5.1   2.6e-06    0.0008       1      39 [.     224     264 ..     224     268 .. 0.86

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 2.6e-06
                 -TTT-S--SS-E.E-TTS--B-CHHHHHHHHC..TSSB--T CS
    zf-C3HC4   1 CpiCleeakepnelleCkHsfCskCirkilks..rkkvkCP 39 
                 C++C  ++ e  ++l C+H++C++C++ i ++     ++CP
  EEA18504.1 224 CALCHRTFNESWKFLGCGHTLCQTCLEDIESKglGFGYPCP 264
                 **************************999876555555565 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   3.2     1e-05    0.0032       1      29 [.     223     251 ..     223     265 .. 0.89

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 1e-05
  zf-C3HC4_2   1 kCpiCldmlkdpsvvtpCgHvfCqkCilr 29 
                 kC++C   +++      CgH+ Cq C+  
  EEA18504.1 223 KCALCHRTFNESWKFLGCGHTLCQTCLED 251
                 7***********9999**********976 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   6.6   9.4e-06    0.0029       1      33 [.     223     253 ..     223     270 .. 0.80

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 9.4e-06
   zf-RING_5   1 hCnkCfeklskeekfyltsCgHifCekClkkll 33 
                 +C  C++ +  +e   ++ CgH++C++Cl    
  EEA18504.1 223 KCALCHRTF--NESWKFLGCGHTLCQTCLEDIE 253
                 699******..9****************98766 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6  18.3   9.2e-06    0.0028     152     245 ..     126     215 ..     120     225 .. 0.73

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 9.2e-06
        Spc7 152 eedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkse 245
                 +++++++ + ++ ++++++e++e +++le+e ++l++++++l++ dke+L++ +e+l++ k+++++ k   ++lq+++++l+ +i+ l+ q++e
  EEA18504.1 126 KREDSNVVDFQSRIKRFVKEVTEPYEALEQENKRLNQESHQLKK-DKEQLQKDKEQLQKDKEQLRKNK---EQLQKDKKQLQLQIQYLRRQIDE 215
                 56778888888999999999999999999999999999999877.88899999998888888888444...44444555555555544444443 PP

>> KASH_CCD  Coiled-coil region of CCDC155 or KASH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1  18.1   1.2e-05    0.0038      72     143 ..     139     210 ..     130     225 .. 0.65

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 1.2e-05
    KASH_CCD  72 lkalvkeleEkrarlkaqnkqlekenqsLiakiesLqeenikllaekdelkkklkeLlkekaeLkkqlhele 143
                 +k++vke+ E  + l+++nk+l++e  +L++  e+Lq + ++l+ +k++l+k +++L k k +L+ q++ l 
  EEA18504.1 139 IKRFVKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLR 210
                 466666666666666666666666666666666666666666666666666666666666666666665443 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0      0.32        99      31      43 ..     222     234 ..     215     237 .. 0.74
   2 !   15.5   3.5   3.8e-05     0.012       1      34 [.     224     264 ..     224     273 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.32
  Prok-RING_4  31 ssCPlCqrrisks 43 
                    C lC+r +++s
   EEA18504.1 222 LKCALCHRTFNES 234
                  48******99876 PP

  == domain 2  score: 15.5 bits;  conditional E-value: 3.8e-05
  Prok-RING_4   1 CvlCgeq.ekkailepCgHlvCkeCfdskdls......sCP 34 
                  C lC +  ++   +  CgH +C++C+++ +++       CP
   EEA18504.1 224 CALCHRTfNESWKFLGCGHTLCQTCLEDIESKglgfgyPCP 264
                  9999998788899***************9988666666666 PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   5.8   2.6e-05    0.0081       2      42 ..     223     265 ..     222     269 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 2.6e-05
   zf-RING_2   2 eCpICleelssadsvlllpCgHvfhreClerwlrssst.....CPl 42 
                 +C++C   ++  +s+  l CgH+ +++Cle+ ++s+       CP+
  EEA18504.1 223 KCALCHRTFN--ESWKFLGCGHTLCQTCLED-IESKGLgfgypCPY 265
                 7****98885..7888889**********99.66666667777996 PP

>> ERM  Ezrin/radixin/moesin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6  16.1   3.5e-05     0.011      28     102 ..     143     217 ..     130     226 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 3.5e-05
         ERM  28 LreseetaelLaekarraeeeaelLeqkaaeaeeeiqrlkesaekeeeekeklerklreaeleaarleeeserke 102
                  +e +e  e L+++++r+ +e+ +L+++++++++ +++l++++e+  ++ke+l+++ ++ +l+++ l+++ ++++
  EEA18504.1 143 VKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDEQK 217
                 566777788899999999999999999999999999999999999999999999999999998888876655443 PP

>> zf-C3HC4_4  zinc finger of C3HC4-type, RING
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   5.3   0.00011     0.033      13      40 ..     237     264 ..     224     268 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 0.00011
  zf-C3HC4_4  13 sleCGhsfClsCisslqkepdgeqllCp 40 
                  l CGh+ C++C++ +  +  g +++Cp
  EEA18504.1 237 FLGCGHTLCQTCLEDIESKGLGFGYPCP 264
                 488*****************9*99***8 PP

>> GAS  Growth-arrest specific micro-tubule binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9  21.2   4.2e-05     0.013      47     102 ..     148     203 ..     124     223 .. 0.64

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 4.2e-05
         GAS  47 kelseisqenkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkelekelk 102
                    ++++qenkrl+++ +++++++e+L+k+ ++ +kdk++l++ k++l++ +k+l+
  EEA18504.1 148 EPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQ 203
                 33456677777777777777777777777777777777777777776666555543 PP

>> zf-C3HC4_5  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.8   4.4   6.3e-05     0.019       4      51 .]     224     269 ..     222     269 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 6.3e-05
  zf-C3HC4_5   4 CPvCkssrYlnpdleflinpeCYhkmCesCvdRlFsdG...PnqCPvagCh 51 
                 C +C  +r +n++ +fl    C h++C++C + + s+G     +CP+++C+
  EEA18504.1 224 CALC--HRTFNESWKFL---GCGHTLCQTCLEDIESKGlgfGYPCPYPECK 269
                 7777..5889******9...7****************9444479******6 PP

>> Ax_dynein_light  Axonemal dynein light chain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6  15.5   7.5e-05     0.023     118     181 ..     154     216 ..     109     223 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 7.5e-05
  Ax_dynein_light 118 eqgkselekkikeLeeekeelekqvaelkaklealekrekerrqeeekkheeeieflkksnqql 181
                      eq++++l+++ ++L+++ke+l+k  ++l++  e+l+k +ke++q+++k+ + +i++l+++  + 
       EEA18504.1 154 EQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRK-NKEQLQKDKKQLQLQIQYLRRQIDEQ 216
                      688889999999****************999999876.57899999999********9997654 PP

>> DUF3450  Protein of unknown function (DUF3450)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0  17.1   7.7e-05     0.024      15      78 ..     154     217 ..     137     221 .. 0.50

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 7.7e-05
     DUF3450  15 aatldqalkeaekavaaaaqsqkkidklddekqellaeyralkeeleslevyneqlerlvasqe 78 
                 +++ + +++e+ +  + ++q qk +++l+++k++l ++ ++l++ +++l+++ ++l+r++++q+
  EEA18504.1 154 EQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDEQK 217
                 3333344444444444455555555555555555555555555555555555555555554444 PP

>> DUF1351  Protein of unknown function (DUF1351)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1  11.0   9.5e-05     0.029     110     193 ..     134     217 ..     123     225 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 9.5e-05
     DUF1351 110 evkaliselaeeaeveleeieiqekwln.ktvslkkieeeieaakaekikkdreelekakaeieekakafeleasaylrllkegk 193
                   +++i+ +++e  +++e +e ++k ln ++ +lkk +e++ +   e+++kd+e+l+k+k++++++ k+++l+ +   r+++e+k
  EEA18504.1 134 DFQSRIKRFVKEVTEPYEALEQENKRLNqESHQLKKDKEQL-QKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDEQK 217
                 567899**************999999997899*********.999***************************9966666777754 PP

>> UPF0242  Uncharacterised protein family (UPF0242) N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3  20.5   0.00011     0.034      85     162 ..     137     217 ..     104     223 .. 0.71

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 0.00011
     UPF0242  85 ktkeealeelqeeeeeLkeeldakeeelerlkeenqqLqekleaiaedfeelkleleeqLaekqe....llqeyqetieeqr 162
                 + ++  ++e++e  e L++e +  ++e+++lk++++qLq+ +e+ ++d e+l+++  eqL++ ++    ++q ++++i eq+
  EEA18504.1 137 SRIKRFVKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNK-EQLQKDKKqlqlQIQYLRRQIDEQK 217
                 4667789999999*******************************999988888765.5555544401114556666666665 PP

>> zf-RING_6  zf-RING of BARD1-type protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   2.3   0.00019      0.06       6      45 ..     220     259 ..     216     273 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 0.00019
   zf-RING_6   6 kllrcsrctdilrepvclggcehifcsncisdcfgsgcpv 45 
                  +l+c+ c   + e   + gc h +c  c+ d    g   
  EEA18504.1 220 NILKCALCHRTFNESWKFLGCGHTLCQTCLEDIESKGLGF 259
                 689***************************9974444333 PP

>> Golgin_A5  Golgin subfamily A member 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9  17.2   0.00019     0.058      82     162 ..     140     220 ..     118     230 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 0.00019
   Golgin_A5  82 aqqqaeaeslreqlqeleeqleeerkakeeveaelerlkeelryleeelvrskatlqsrikdrekeieklrnqlttkslss 162
                 +++ +e+ +  e l++ +++l++e+++ ++ +++l++ ke+l+  +e+l+++k++lq+  k+ + +i+ lr+q+  ++  +
  EEA18504.1 140 KRFVKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDEQKRRN 220
                 567788888888899999999999999999999999999999999999999999999999999999999999998776655 PP

>> DUF3584  Protein of unknown function (DUF3584)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7  15.1   0.00022     0.068     803     909 ..     113     219 ..      95     231 .. 0.52

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00022
     DUF3584 803 lqetwlkvdslaeerpalkeqveelesaaeeleqeltrliedtklerkklekerkalekqldqldenlrklrdllskl..aelkldadaeqaegelaer 899
                 + +  ++   ++++r++  ++v + +s +++  +e t+  e++++e+k+l++e++ l+k ++ql++ + +l++  ++l  ++ +l++d++q++++++  
  EEA18504.1 113 MEHAISA--PTVGKRKREDSNVVDFQSRIKRFVKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLrkNKEQLQKDKKQLQLQIQYL 209
                 4444433..445555555555555555555555555555555555555555555555555555555555555555555333333444444555555555 PP

     DUF3584 900 laaleelkrk 909
                  ++++e kr+
  EEA18504.1 210 RRQIDEQKRR 219
                 5555554443 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2  12.8    0.0003     0.094     126     199 ..     124     209 ..      74     220 .. 0.68

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 0.0003
      AAA_23 126 gskkiilnlilflgqer...........feefelkdkkerleelekeleeledekkllekl.eqekekekeleeleeeleeilkel 199
                 ++k + +n+++f+   +           + e+e+k+ +++  +l+k++e+l+++k++l+k  eq+ +++++l++ +++l+ ++++l
  EEA18504.1 124 KRKREDSNVVDFQSRIKrfvkevtepyeALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDkEQLRKNKEQLQKDKKQLQLQIQYL 209
                 34444555555555444555555666654455567777788888888888877777666664677777778888888887776655 PP

>> COG5  Golgi transport complex subunit 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.1   0.00078      0.24      79     111 ..     130     162 ..     125     170 .. 0.88
   2 ?    3.5   4.2      0.24        76      19      56 ..     183     220 ..     173     225 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00078
                 XXXXXXXXXXXXXX-TTHHHHHHHHHHHHHHHH CS
        COG5  79 sslesLsasyerlkskvlepyeeaeklqsalkr 111
                 s++ + ++ ++r  ++v+epye +e+ +++l++
  EEA18504.1 130 SNVVDFQSRIKRFVKEVTEPYEALEQENKRLNQ 162
                 7889999********************999875 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.24
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        COG5  19 katnnnddteldlstplkrlnydiqeldkrlrqlitsn 56 
                 k +++ +++++ l+   k+l+  iq l+++++++ ++n
  EEA18504.1 183 KDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDEQKRRN 220
                 467778899999********************987776 PP

>> ADIP  Afadin- and alpha -actinin-Binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3  20.3   0.00045      0.14      54     115 ..     156     217 ..     123     223 .. 0.61

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00045
        ADIP  54 qreslnetirkleaeierlqskierlktqleqlerelalvqakerqlekklktleqklknek 115
                 +++ ln++ ++l+ ++e+lq++ e+l++  eql++  +++q++++ql+ +++ l +++ ++k
  EEA18504.1 156 ENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDEQK 217
                 34556666666666666666666666666666666666666666666666666666666555 PP

>> V_ATPase_I  V-type ATPase 116kDa subunit family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   8.8   0.00041      0.13      63     137 ..     135     207 ..     100     235 .. 0.53

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00041
  V_ATPase_I  63 leapeekeldeleeelekleeelkelnenleklkkelnelvelkavlekakefleeeeeeeeeeeseeeeeekee 137
                  +++ ++ ++e++e  e le+e k+ln+++++lkk++++l++ k+ l+k ke l++++e+ ++++++ +   + +
  EEA18504.1 135 FQSRIKRFVKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQL--QIQ 207
                 3334444555555555666666666666666666666666666666666666665442222222211111..111 PP

>> zf-C4H2  Zinc finger-containing protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7  11.6   0.00075      0.23      21     104 ..     131     214 ..     119     228 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00075
     zf-C4H2  21 kevealekeekcleeykkelelLeqEkmaHveeLrlIhaDinalEsvikeaeeekekslekakklyeeykklkeevnelrselg 104
                 + v++ ++ +++++e+++  e LeqE +   +e  ++++D+++l +  ++ +++ke+  ++ ++l ++ k+l+ +++ lr+++ 
  EEA18504.1 131 NVVDFQSRIKRFVKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQID 214
                 56788899999*****************999999**********9999999999999999999999999999999999998764 PP

>> FapA  Flagellar Assembly Protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4  12.4   0.00058      0.18     323     417 ..     134     222 ..     112     232 .. 0.67

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00058
        FapA 323 kteiev.gldepelkeklkeleeeleeleeeleklkkkikklpklkaekqlesekkeqlkklletkeklkeeleeleeelkelkeeleskkeeaki 417
                  ++ ++  +  +e+ e +++le+e ++l++e ++lkk+ ++l+k       +++ +++ ++l+++ke+l+++ ++l+ ++++l  +++++k+ +++
  EEA18504.1 134 DFQSRIkRFV-KEVTEPYEALEQENKRLNQESHQLKKDKEQLQK------DKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDEQKRRNIL 222
                 4444444444.566666777777777777777777777666666......3345568888899999999999999999999999999988655544 PP

>> JIP_LZII  JNK-interacting protein  leucine zipper II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4  12.8   0.00091      0.28       6      66 ..     149     209 ..     143     213 .. 0.93

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00091
    JIP_LZII   6 evenLikENteLletknaLnvvkddLIarvdeLtsereiLreEleslqkakerlesrikel 66 
                   e L +EN++L +    L   k+ L +  ++L++++e Lr+  e+lqk k++l+ +i+ l
  EEA18504.1 149 PYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYL 209
                 5799****************************************************99866 PP

>> FTO_NTD  FTO catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   3.5   0.00078      0.24      56     155 ..      91     203 ..      82     221 .. 0.68

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00078
     FTO_NTD  56 lTavsRlLvGepGlTYk.yldlRlFalPWseeekeakaalke..........dpeiesalkallklndvlaeeakkllekrklak.dkee.sesgegls 141
                  T  +R   G+p +TY+ y+d+   a+  ++ +k ++ +++            +e+++ ++al + n+ l++e+++l++ +++ + dke+ ++++e+l 
  EEA18504.1  91 HTRPRRRRRGRPDYTYRdYQDTMEHAISAPTVGKRKREDSNVvdfqsrikrfVKEVTEPYEALEQENKRLNQESHQLKKDKEQLQkDKEQlQKDKEQLR 189
                 566677778999999998999988888777777776666554678888888889999999999999999999999998877665513333122222222 PP

     FTO_NTD 142 aasaaqtsqskele 155
                 +++++ + ++k+l+
  EEA18504.1 190 KNKEQLQKDKKQLQ 203
                 22333333444444 PP

>> Jnk-SapK_ap_N  JNK_SAPK-associated protein-1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6  18.2    0.0016      0.49      56     123 ..     150     217 ..     122     225 .. 0.63

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.0016
  Jnk-SapK_ap_N  56 reeleqLeteyerekelrkraeeeleeiedqweeerkelqekveqleeenrelelkaknaadqlsrle 123
                     e+leq  +++++e ++ k+ +e+l++  +q+++++++l++  eql++++++l+l+++ +  q+ + +
     EEA18504.1 150 YEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDEQK 217
                    23333333333345555556666667777777777777777777777777777777666666666554 PP

>> Prominin  Prominin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   5.2     0.001      0.32     625     705 ..     131     217 ..     114     244 .. 0.74

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.001
    Prominin 625 nletlaekleelanelsngk.......knlkqslkneaqdlraiqqelvlplessvkklkksvkkldeensdlqesikkllaaverae 705
                 n+  ++++++ + +e+++ +       k l+q+ ++ ++d +++q+++ ++l++  ++l+k+ ++l++++++lq +i+ l +++++ +
  EEA18504.1 131 NVVDFQSRIKRFVKEVTEPYealeqenKRLNQESHQLKKDKEQLQKDK-EQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDEQK 217
                 555666666666666666654443333566666666666666666665.468888999999999999999999999999999988754 PP

>> Macoilin  Macoilin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0  11.7    0.0015      0.45     377     495 ..     107     219 ..      56     233 .. 0.48

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.0015
    Macoilin 377 aalkdaaenslpnnqlskkda........lvrLeadikkLkaeLqasrqteqelrskissltseerslkselqqlkkendllqtklhelvsakqkdkqt 467
                 +  +d++e+ ++  +++k++           r+   +k              e+ + +++l +e++ l +e +qlkk++++lq+  ++l + k + +++
  EEA18504.1 107 RDYQDTMEHAISAPTVGKRKRedsnvvdfQSRIKRFVK--------------EVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKN 191
                 45667777777777776554434444443223333333..............33333333333333333333333333333333333333333333333 PP

    Macoilin 468 lqqlekrLkeekearaslekqLaeekkr 495
                  +ql+k  k+ + + + l +q+ e+k+r
  EEA18504.1 192 KEQLQKDKKQLQLQIQYLRRQIDEQKRR 219
                 3333333333333333333333333333 PP

>> 5_nucleotid  5' nucleotidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   9.7    0.0022      0.69     330     402 ..     143     217 ..     127     235 .. 0.86

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0022
                  -TTHHHHHHHHHHTHHH..HHHHHHHHHHHHHHHHHHHHHHHT.TTHHHHHHHHHHHHHHHHHHHHHHHHHHCCS CS
  5_nucleotid 330 vpELeeElevleekkek..eeleelekleelledelkklksseeeskekleeleedleelkkeirelreelkelf 402
                  v+E++e +e+le+++++  +e ++l+k +e+l++  ++l+  +e+ ++++e+l++d ++l+ +i+ lr++++e+ 
   EEA18504.1 143 VKEVTEPYEALEQENKRlnQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDEQK 217
                  789999999999998888899999999999999999999998777788889999999999999999999998865 PP

>> HALZ  Homeobox associated leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   3.9    0.0035       1.1      21      40 ..     150     169 ..     144     172 .. 0.89
   2 ?    3.3   8.8      0.31        95      17      39 ..     167     189 ..     165     192 .. 0.61
   3 ?    4.7  15.6      0.11        35       2      40 ..     173     211 ..     172     214 .. 0.95

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0035
        HALZ  21 ydsLkkenekLkaelqeLke 40 
                 y++L++en++L +e ++Lk+
  EEA18504.1 150 YEALEQENKRLNQESHQLKK 169
                 9*****************97 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.31
        HALZ  17 LksdydsLkkenekLkaelqeLk 39 
                 Lk d ++L+k++e+L++  ++L+
  EEA18504.1 167 LKKDKEQLQKDKEQLQKDKEQLR 189
                 66666666666666666655555 PP

  == domain 3  score: 4.7 bits;  conditional E-value: 0.11
        HALZ   2 QLErDYdvLKasYdaLksdydsLkkenekLkaelqeLke 40 
                 QL +D + L+++ ++L+ + ++L+k++++L+ ++q L+ 
  EEA18504.1 173 QLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRR 211
                 9999*******************************9986 PP

>> CENP-H  Centromere protein H (CENP-H)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1  14.4    0.0053       1.7      23      83 ..     144     203 ..     128     222 .. 0.60

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0053
      CENP-H  23 relqeeltevekenlrlkrknrelaaellelakekesekeklkeelekleaelkksrqrwr 83 
                 +e++e  + +e+en+rl++++++l ++ ++l+k+ke+ + k+ke+l k +++l+k +++ +
  EEA18504.1 144 KEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQ-KDKEQLRKNKEQLQKDKKQLQ 203
                 555555666666666666666666666666666666665.344444444444444444432 PP

>> Dor1  Dor1-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   2.8     0.051        16       6      36 ..     147     177 ..     143     181 .. 0.90
   2 ?    7.4   5.9    0.0051       1.6       6      37 ..     182     213 ..     178     236 .. 0.76
   3 ?    0.5   0.0      0.63   1.9e+02     196     217 ..     235     256 ..     229     259 .. 0.88

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.051
        Dor1   6 skpleelekepelLaeeaeeilaqiqdLark 36 
                 + p+e+le+e ++L +e++++++   +L+++
  EEA18504.1 147 TEPYEALEQENKRLNQESHQLKKDKEQLQKD 177
                 679********************99999876 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0051
        Dor1   6 skpleelekepelLaeeaeeilaqiqdLarkn 37 
                 +k+ e+l+k++e+L++++++++ qiq L r++
  EEA18504.1 182 QKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQI 213
                 67889*********************998875 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.63
        Dor1 196 lkflqsrdavLekileeldtkn 217
                  kfl++    ++++le+++ k+
  EEA18504.1 235 WKFLGCGHTLCQTCLEDIESKG 256
                 59****************9876 PP

>> HemX  HemX, putative uroporphyrinogen-III C-methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8  16.0    0.0057       1.8      37     102 ..     150     212 ..     134     222 .. 0.61

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0057
        HemX  37 vaelqqqlaaleqqlaqveaekeqkqeleerlqqlaeklealekeleqlqkqleelqqqlskvsga 102
                  ++l+q+ + l+q+++q   +k++k++l+++ +ql+++ e+l+k++eqlqk+ ++lq q++ +  +
  EEA18504.1 150 YEALEQENKRLNQESHQ---LKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQ 212
                 36777777777777777...4444444445555555556666666666666666666666665544 PP

>> FemAB  FemAB family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   9.9    0.0058       1.8     242     307 ..     155     204 ..     132     238 .. 0.53

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0058
       FemAB 242 eylkelqekleklekklakleekleknpekkkkkklkelekqlaslekelkeaeefiekdgeevvl 307
                 +  k+l+++ ++l                kk+k++l++ ++ql++ +++l++ +e+ +kd++++ l
  EEA18504.1 155 QENKRLNQESHQL----------------KKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQL 204
                 2233333333344................5555555555555555555555555555555544333 PP

>> DUF4795  Domain of unknown function (DUF4795)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8  16.9    0.0073       2.3       9      70 ..     143     208 ..     126     209 .. 0.85
   2 ?   10.1  11.5    0.0015      0.46      11      58 ..     173     220 ..     172     226 .. 0.92

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0073
     DUF4795   9 lkklqeaieklqeelekleekvkelekrledkekklealkkqieelekvk....adkeeveeelae 70 
                 +k++ e +e l++e ++l+++ ++l+k++e+++k+ e l+k  e+l+k+k    +dk+++++++++
  EEA18504.1 143 VKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKeqlqKDKKQLQLQIQY 208
                 788889999999999999999999999999999999999999999999998888889999988876 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.0015
     DUF4795  11 klqeaieklqeelekleekvkelekrledkekklealkkqieelekvk 58 
                 +lq++ e+lq+++e+l + +++l+k++++++ +++ l+ qi+e + ++
  EEA18504.1 173 QLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDEQKRRN 220
                 89***************************************9977765 PP

>> TMPIT  TMPIT-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4  13.1    0.0075       2.3       6      79 ..     145     217 ..     124     231 .. 0.61

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0075
       TMPIT   6 elekefkeleetakeykqkleelsklqskcskeikkqkkrlkelksslkklkksvkeeeeeeveelkeelkerk 79 
                 e+++ +++le+++k+++q++++l+k +++++k+ ++ +k+ ++l+++ ++l+k++ ++ + +++ l+++++e+k
  EEA18504.1 145 EVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDK-KQLQLQIQYLRRQIDEQK 217
                 5555555555555555555555555555555555555555555555555555552.344445555555555444 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6  11.6     0.012       3.7      43     119 ..     139     215 ..     131     220 .. 0.88

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.012
     DUF1664  43 vesvskqleqvseslaatkrhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeavegleskler 119
                 +++  k++++ +e+l++  ++L+++ +++ k  ++ ++ +++++++ +++r++ +++++d ++++  ++ l  ++++
  EEA18504.1 139 IKRFVKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDE 215
                 5566688888999999999***********9999999999*************************999999999976 PP

>> NRBF2  Nuclear receptor-binding factor 2, autophagy regulator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   7.0    0.0013      0.41      88     123 ..     143     178 ..     109     186 .. 0.70
   2 ?    3.3   8.6      0.17        53      92     130 ..     168     204 ..     167     216 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.0013
       NRBF2  88 iadLkrlvelLlaenerLrkenkqLkaekaRLqkep 123
                 ++++    e L +en+rL +e +qLk +k +Lqk+ 
  EEA18504.1 143 VKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDK 178
                 344555568899999999999999999999999876 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.17
       NRBF2  92 krlvelLlaenerLrkenkqLkaekaRLqkeplekeldv 130
                 k+  e+L ++ e+L+k+ +qL+ +k +Lqk+   k+l+ 
  EEA18504.1 168 KKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDK--KQLQL 204
                 66667788888888888888888888888877..44443 PP

>> DivIVA  DivIVA protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   6.1    0.0006      0.19      23      67 ..     139     183 ..     136     185 .. 0.94
   2 ?    1.8   4.2      0.74   2.3e+02      29      60 ..     187     218 ..     183     226 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.0006
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCTXXXXXXXXXXXXX CS
      DivIVA  23 VdeFLdqvakdyeallkeneelkekvkeleeklkeykeleetLkk 67 
                 +++F ++v++ yeal +en++l+++ ++l+++ ++ ++ +e+L+k
  EEA18504.1 139 IKRFVKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQK 183
                 789***************************************997 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.74
                 HHHHHHHHHHHHHHHHHHHHHCCCCTXXXXXX CS
      DivIVA  29 qvakdyeallkeneelkekvkeleeklkeyke 60 
                 q+ k+ e+l k++++l+ +++ l+++++e k 
  EEA18504.1 187 QLRKNKEQLQKDKKQLQLQIQYLRRQIDEQKR 218
                 56677788888888888888888888887765 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5  12.1    0.0098         3     111     185 ..     137     217 ..      85     229 .. 0.50

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0098
      AAA_11 111 ekvekrlekee.kaqlakeiskeleklakelrafeeeeek.....eklkkskekskskleqerrklkkerkelskeleeae 185
                 +++++  ++ +   +  ++ +k+l++++++l++++e+ +k     +k k++ +k+k++l++++++l+ +++ l+++++e++
  EEA18504.1 137 SRIKRFVKEVTePYEALEQENKRLNQESHQLKKDKEQLQKdkeqlQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDEQK 217
                 222222222212222333333333333344433433333222222344455555555555555555555555555555444 PP

>> Presenilin  Presenilin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   3.9    0.0083       2.6     270     316 ..     140     200 ..      79     260 .. 0.52

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0083
  Presenilin 270 e...............seeeseeesseaessaeesseekeseessesseeeeeeeeeeeese 316
                 +               ++++ ++es++ ++++e+ +++ke+ + +++++ ++++e+ +++++
  EEA18504.1 140 KrfvkevtepyealeqENKRLNQESHQLKKDKEQLQKDKEQLQ-KDKEQLRKNKEQLQKDKK 200
                 0333333333333322222222222222222222222222111.112222222222222222 PP

>> DUF3552  Domain of unknown function (DUF3552)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6  22.9     0.015       4.5      69     135 ..     142     208 ..     125     216 .. 0.89

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.015
     DUF3552  69 lekelkerrnelqrlekRllqkeetLdrkeeslekkeesleekekelkqkeqsleekeeeleelvee 135
                 + ke++e  + l++ +kRl+q   +L++ +e+l+k  e+l++ +++l++++++l++ +++l+  ++ 
  EEA18504.1 142 FVKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQY 208
                 55899999999*************************************************9987765 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   5.0     0.023         7      26      65 ..     138     177 ..     126     183 .. 0.44
   2 ?    4.5  10.6      0.17        53      11      58 ..     172     219 ..     169     245 .. 0.89

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.023
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHXXXXXXXXXXXXX CS
        YabA  26 elkeelaelleenaeLeleneklrerleeeekkekekkke 65 
                 ++k+ ++e++e  ++Le en++l ++ ++ +k++++ +k+
  EEA18504.1 138 RIKRFVKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKD 177
                 3444444555555555555555544442222222222221 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.17
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHXXXXXX CS
        YabA  11 eeleeqleelleeleelkeelaelleenaeLeleneklrerleeeekk 58 
                 e+l+++ e+l+++ e+l+++ ++l ++ ++L+l+ + lr++++e++++
  EEA18504.1 172 EQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDEQKRR 219
                 68999999**********************************666554 PP

>> Prefoldin_2  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3  12.5      0.51   1.6e+02      62      98 ..     148     184 ..     140     187 .. 0.82
   2 ?    7.4  11.3     0.013       4.1      64      97 ..     185     218 ..     180     223 .. 0.88

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.51
                  HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Prefoldin_2  62 evkeeLeerketlekeiktlekqleklekeleelkee 98 
                  e  e Le++ ++l++e+ +l+k +e+l+k+ e+l++ 
   EEA18504.1 148 EPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKD 184
                  5557899999999999999999999999999999985 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.013
                  HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Prefoldin_2  64 keeLeerketlekeiktlekqleklekeleelke 97 
                  ke+L ++ke+l+k  k+l+ q+++l+++++e+k 
   EEA18504.1 185 KEQLRKNKEQLQKDKKQLQLQIQYLRRQIDEQKR 218
                  799**************************99986 PP

>> DUF1943  Domain of unknown function (DUF1943)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4  10.1      0.03       9.4      83     163 ..     163     253 ..      65     258 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.03
     DUF1943  83 k...........ksekekkeeskrrkrsvqkrk.qdikeeikkkleklakklkidkeepeekeaslylklfGnelaflsideqaeqealeqii 163
                 +           +++ke+++++k + r+ +k++ q++k++++ +++ l ++++++k+  +  ++ l  + f++ ++fl ++  ++q+ le+i+
  EEA18504.1 163 EshqlkkdkeqlQKDKEQLQKDKEQLRK-NKEQlQKDKKQLQLQIQYLRRQIDEQKR-RNILKCALCHRTFNESWKFLGCGHTLCQTCLEDIE 253
                 1333455555664444444333333333.334567899*****************88.5688*******************999999888876 PP

>> Seryl_tRNA_N  Seryl-tRNA synthetase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4  19.5     0.033        10      14      98 ..     135     214 ..     124     221 .. 0.64

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.033
                   HHHHHCCCTCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTTS-TCCCCCCCHHHHHHHHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N  14 vkeklkkRgedkadvdelleldekrrelqveleelqaerNelskeIgkakkkkedaeeliaevkelkeelkaleaelkeleaele 98 
                   ++ ++ kR+  k+  + + +l+++ ++l++e  +l++ + +l+k  +++ k+k   e+l++  ++l+++ k+l+ + + l+ +++
    EEA18504.1 135 FQSRI-KRF-VKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDK---EQLRKNKEQLQKDKKQLQLQIQYLRRQID 214
                   34444.454.7788888889999999999999999999999999888888776...44444445555555555444444444443 PP

>> UPF0449  Uncharacterised protein family UPF0449
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7  10.1     0.065        20      57      98 ..     143     184 ..      67     187 .. 0.76
   2 ?    5.7   8.0     0.066        21      71     100 ..     178     207 ..     176     215 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.065
     UPF0449  57 veelYeqvrtylelnerLeeakeeLkqkceeLktageeLeee 98 
                 v e+ e  +++ + n+rL++++++Lk+  e+L++  e+L+++
  EEA18504.1 143 VKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKD 184
                 44455555566678999999******999***9999999986 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.066
     UPF0449  71 nerLeeakeeLkqkceeLktageeLeeeie 100
                 +e+L++ ke+L+++ e+L++  ++L+ +i+
  EEA18504.1 178 KEQLQKDKEQLRKNKEQLQKDKKQLQLQIQ 207
                 689999999999999999999999998886 PP

>> Neur_chan_memb  Neurotransmitter-gated ion-channel transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   5.3     0.028       8.8     123     204 ..     136     219 ..      55     227 .. 0.64

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.028
                     --------------------------------------SS---TTGGG--.......-----TTTTTHHHHHHHHHHHHHHHHH CS
  Neur_chan_memb 123 ssgasseaeelilskskseskkaklseeqgsekastckckckegeeaspstqlsk..eelspelkkavegvkyiadhlraeded 204
                     +s  ++  +e++   +  e ++++l++e+++ k+++++ ++++++ +++++ql+k  e+l+++ k+   +++y ++++ +++  
      EEA18504.1 136 QSRIKRFVKEVTEPYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKnkEQLQKDKKQLQLQIQYLRRQIDEQKRR 219
                     222222333333333333678888888888888888888888888888888777777778888888888888888888877765 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4  11.9     0.032       9.9     137     224 ..     134     218 ..     104     229 .. 0.52

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.032
     DUF4407 137 eleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaakekkaqldaaqaelaelkakldatarlaalraelaelea 224
                 + +++i++  +e+++  ++l+++++ +++e ++ k+++ ++ + + +  ++ k+ql + +++l++ k++   + +++ lr++++e ++
  EEA18504.1 134 DFQSRIKRFVKEVTEPYEALEQENKRLNQESHQLKKDK-EQLQKDKEQLQKDKEQLRKNKEQLQKDKKQ--LQLQIQYLRRQIDEQKR 218
                 33344444444444444444444444444444322222.224455555555555555555555555555..55666666666555443 PP

>> LMBR1  LMBR1-like membrane protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   6.3     0.031       9.5     255     321 ..     149     209 ..      85     244 .. 0.46

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.031
       LMBR1 255 Peeiaeklksnenkteeslaklekqlikalqkrertekqwkrllekalelediiknksskekefkss 321
                 P e+ e+ ++  n+   +l+k ++ql+k  ++ ++ ++q++++ e+        k+k++ + +++ +
  EEA18504.1 149 PYEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQL------QKDKKQLQLQIQYL 209
                 11111111112222222333333333333333333333333333333......22233333333222 PP

>> SseC  Secretion system effector C (SseC) like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   8.3     0.035        11     252     287 ..     172     207 ..     140     217 .. 0.55

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.035
        SseC 252 AklqkkaaqlqAdtkllravleqlqkvldeaaeeik 287
                  +lqk+ +qlq d+++lr+  eqlqk +++++ +i+
  EEA18504.1 172 EQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQ 207
                 233333344444444444444444444444444443 PP

>> DUF2968  Protein of unknown function (DUF2968)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3  24.0     0.043        13     108     173 ..     150     215 ..     135     220 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.043
     DUF2968 108 kaqlerqiaasearaerLqadlavarqQeqavaerQkqarkeaaaLeaqreaaqaqlralqrqirq 173
                 ++ le++ ++ +++ ++L++d +  ++ ++++++  +q+rk+ ++L+++++++q q++ l+rqi++
  EEA18504.1 150 YEALEQENKRLNQESHQLKKDKEQLQKDKEQLQKDKEQLRKNKEQLQKDKKQLQLQIQYLRRQIDE 215
                 566777778888888889999998888999999999999999999999999999999999999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (285 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3428  (0.191199); expected 358.6 (0.02)
Passed bias filter:                     1067  (0.0595125); expected 358.6 (0.02)
Passed Vit filter:                       300  (0.0167327); expected 17.9 (0.001)
Passed Fwd filter:                        75  (0.00418317); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              58  [number of targets reported over threshold]
# CPU time: 0.98u 0.44s 00:00:01.42 Elapsed: 00:00:00.60
# Mc/sec: 1439.25
//
Query:       EEA18505.1  [L=819]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
   7.5e-152  506.1   2.1   7.5e-152  506.1   2.1    1.6  2  DUF3435      Protein of unknown function (DUF3435)
  ------ inclusion threshold ------
        1.4    7.1   9.3      0.036   12.4   2.2    1.8  2  CDC45        CDC45-like protein


Domain annotation for each model (and alignments):
>> DUF3435  Protein of unknown function (DUF3435)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.9      0.22     2e+03     303     347 ..     129     173 ..     116     183 .. 0.66
   2 !  506.1   2.1  8.4e-156  7.5e-152       1     417 [.     278     690 ..     278     691 .. 0.98

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.22
     DUF3435 303 eleakygqvakakgtelyeelekakrelrnerqrlrrelkkkire 347
                 ++e  +++ +++++    e  ++++++lr+++ r  r+ +kk+r+
  EEA18505.1 129 DVETDHESSDDEEDDGYAESTKEQREKLRSRWERFCRRKRKKART 173
                 455555666666666666666667777777777777777666664 PP

  == domain 2  score: 506.1 bits;  conditional E-value: 8.4e-156
     DUF3435   1 ieDllellrvlltttekrfqlgrqrvqlllllllaaftsnRpgalleLryrDleltlikdPeggrpvllvevtpeftKgklGkkkkntfvlPeiiydps 99 
                 ieDl++l++++l+t+ekrf+lg+qr+q +l++ la ft+nR +a+ +L+y++l+ ++++dP+gg+p +l+e+t +f K++lG +++ntf +Peiiydps
  EEA18505.1 278 IEDLVPLQETVLRTQEKRFWLGLQRIQQCLYNVLACFTVNRIDAMRNLQYKHLQCSMQRDPRGGPPIILLEITNKFAKKYLGVTQANTFPIPEIIYDPS 376
                 8************************************************************************************************** PP

     DUF3435 100 LvlsPhvfllgllfrdeAFkspsltsaedlyrlkvpkgrqqlpLklkpemldipvFcraereaegvrilkdealtastlnsrlkrlgeiagfeepitpY 198
                 L+lsPh+fllg+l+r +AF++p+l+s+edl+rl + kgrqqlpL+lkpem++++vFcr+e + ++v++ ++ ++t+ tl ++++ +geiagf  +++ +
  EEA18505.1 377 LMLSPHSFLLGMLLRNQAFRAPNLRSMEDLRRLFIGKGRQQLPLPLKPEMANYYVFCRVEAKRGKVTVNPKLPITKATLTKQIRDFGEIAGFPWAVFTH 475
                 *************************************************************************************************** PP

     DUF3435 199 klRrgaakalneSgevseaqrnlilqHassrtFlkhYlsqkvdkdvqavvlglppqealiraassmsrsiDprrPkeLtdeqkasveedpelqelkrkr 297
                 ++R+g++ ++n Sg vs+a++nli++H +srtFl+hYl+++vd+d+qa+++gl+p+++l+ra+++m+r++DprrP+eLtdeqkasve++pel ++++kr
  EEA18505.1 476 RFRYGGGTIMNASGLVSDAKQNLIMKHRDSRTFLNHYLPRRVDVDMQALMRGLEPDSELMRAVTRMGRWMDPRRPRELTDEQKASVEDEPELIKAIEKR 574
                 *************************************************************************************************** PP

     DUF3435 298 eelkkeleakygqvakakgtelyeelekakrelrnerqrlrrelkkkireeFkeeqpvidierqlsGkaldee.vkedledeqlvpperarlidllltl 395
                 ++l+ el+      +++k+  + ++l+++k+ ++n+rqrl ++l+ ++r +F++eq+vidie+ql+G+a++++  ke l++e+ +ppe   l ++l+t+
  EEA18505.1 575 DRLALELQ-----SQSRKNEVRLARLKRLKKAVTNTRQRLLYALRSRVRRDFDDEQAVIDIEQQLAGTAVTDDeTKERLQKEDRMPPELVTLNEKLMTW 668
                 ****9443.....344445555789*********************************************99999************************ PP

     DUF3435 396 ptsetledelerRiaaidavva 417
                 pts+++e+e++rR++a++av+ 
  EEA18505.1 669 PTSDSIEAEWRRRNEAVEAVLV 690
                 *******************975 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   2.2     4e-06     0.036     121     208 ..     105     171 ..      91     236 .. 0.52
   2 ?   -2.1   0.8     0.097   8.7e+02     197     244 ..     573     620 ..     520     656 .. 0.65

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 4e-06
       CDC45 121 eayealeeeeesdeedeeeeeeddddeeeeeeeeedeedeeedeeeskkkrksksdeeeesddddersrkrrrsepsakklrrqlkke 208
                 +a ++l+e + s+++d +e++++d d e+++e+++deed+                    ++++++r++ r+r+e   +  rr++kk+
  EEA18505.1 105 NAAFRLDEGDFSESSD-DEDSDSDPDVETDHESSDDEEDDGYA-----------------ESTKEQREKLRSRWE---RFCRRKRKKA 171
                 3333333333332111.11111111111111111111111111.................111222222222222...1111111111 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.097
       CDC45 197 sakklrrqlkkerrkyeavlekyysqgtsygesvsslmYsLaselgre 244
                 ++++l  +l+++ rk+e +l++  +  + + +    l+Y+L s ++r+
  EEA18505.1 573 KRDRLALELQSQSRKNEVRLARLKRLKKAVTNTRQRLLYALRSRVRRD 620
                 222333446666666666777777777777777777777777766665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (819 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1147  (0.0639746); expected 358.6 (0.02)
Passed bias filter:                      601  (0.0335211); expected 358.6 (0.02)
Passed Vit filter:                        73  (0.00407162); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.93u 0.33s 00:00:01.26 Elapsed: 00:00:00.56
# Mc/sec: 4383.17
//
Query:       EEA18506.1  [L=170]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-07   31.6   0.0    1.9e-07   31.1   0.0    1.1  1  Bys1      Blastomyces yeast-phase-specific protein


Domain annotation for each model (and alignments):
>> Bys1  Blastomyces yeast-phase-specific protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.1   0.0   1.1e-11   1.9e-07      54     143 ..      58     153 ..      41     167 .. 0.76

  Alignments for each domain:
  == domain 1  score: 31.1 bits;  conditional E-value: 1.1e-11
        Bys1  54 sgdgvsltlshtegrdss.nsettfrykladdnstveyslgnsggnpfeghkltl...kssddrcpriewpegi.ptgvss.gscgssenliltlc 143
                 s  gv + ls +    s+  ++  f y+l  +   v y+l n  g pf+g ++t+   +++++ c ri+w  g+ p g++    cg    l l  c
  EEA18506.1  58 SYGGVDIKLSTAPEAVSTcSAQMFFTYNLVIERGQVWYALNNIYGSPFHGEQVTVvpvNPTGELCTRIKWRAGVsPRGLTRvYWCGRPTSLHLYAC 153
                 55689999988766655515567899***************************97232678999*********86889875156999888888777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (170 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       257  (0.0143343); expected 358.6 (0.02)
Passed bias filter:                      225  (0.0125495); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.25s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 1242.91
//
Query:       EEA18507.1  [L=128]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
     0.0047   16.6   1.2     0.0084   15.8   1.2    1.3  1  zf-C2H2_10     C2H2 zinc-finger
  ------ inclusion threshold ------
      0.011   15.8   0.7      0.015   15.4   0.7    1.1  1  GlnD_UR_UTase  GlnD PII-uridylyltransferase
      0.036   13.8   0.1      0.053   13.3   0.1    1.2  1  zf-CCHC_4      Zinc knuckle
      0.087   12.9   2.1       0.14   12.3   2.1    1.3  1  zf-CCHC        Zinc knuckle


Domain annotation for each model (and alignments):
>> zf-C2H2_10  C2H2 zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   1.2   1.9e-06    0.0084       5      20 ..     109     124 ..     109     125 .. 0.93

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 1.9e-06
  zf-C2H2_10   5 tCSYChetGHtRAkCe 20 
                 +CS C e GH+R +C 
  EEA18507.1 109 RCSNCWELGHKRNRCP 124
                 5**************5 PP

>> GlnD_UR_UTase  GlnD PII-uridylyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.4   0.7   3.3e-06     0.015      56     120 ..      18      86 ..      11      98 .. 0.86

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 3.3e-06
  GlnD_UR_UTase  56 rstlealeelvergllteeeakelreayrflrrlehrLqlladrqthrLpfde....eeqrrlaealgy 120
                    ++t +al++l +  l+t ++a+ l +  + lr+    Lq ++ r+ + Lp +     +e r+la+al+ 
     EEA18507.1  18 TPTSQALDQLLKGALITMHNAAILTSENHKLREAVDQLQKRRTRRAQALPNEGiltvSEGRELAQALDQ 86 
                    57889*********************************************9976666677777777764 PP

>> zf-CCHC_4  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.1   1.2e-05     0.053      34      48 ..     110     124 ..     105     125 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.2e-05
   zf-CCHC_4  34 CyiCgvlGHsdkrCd 48 
                 C++C  lGH+++rC+
  EEA18507.1 110 CSNCWELGHKRNRCP 124
                 **************8 PP

>> zf-CCHC  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   2.1   3.1e-05      0.14       2      18 .]     109     125 ..     108     125 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 3.1e-05
                 CTSSSSSSSSTTTTSTS CS
     zf-CCHC   2 kCynCGepGHiardCpk 18 
                  C nC e GH  + Cp+
  EEA18507.1 109 RCSNCWELGHKRNRCPN 125
                 7***************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (128 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1266  (0.0706119); expected 358.6 (0.02)
Passed bias filter:                      783  (0.0436723); expected 358.6 (0.02)
Passed Vit filter:                        79  (0.00440627); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.41u 0.27s 00:00:00.68 Elapsed: 00:00:00.41
# Mc/sec: 926.39
//
Query:       EEA18508.1  [L=226]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.4e-15   57.4   0.0    1.9e-15   56.9   0.0    1.2  1  DDE_1        DDE superfamily endonuclease
     0.0003   20.7   0.3    0.00078   19.4   0.0    1.9  2  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
        0.1   12.4   0.0       0.38   10.5   0.0    1.7  2  DDE_3        DDE superfamily endonuclease


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.9   0.0   3.2e-19   1.9e-15       2     100 ..     115     216 ..     114     225 .. 0.93

  Alignments for each domain:
  == domain 1  score: 56.9 bits;  conditional E-value: 3.2e-19
       DDE_1   2 erltvllcanaagsekLkplvigkaksprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrle..aekrkilLlldssrshetvel.lese 96 
                 ++++++++++ + +   +pl+i+k+ + +a ++ +    + d++++ + k+w++++++ +WL k+f++ ++   ++ + lL+ld++ sh t e+   +e
  EEA18508.1 115 REWVTVVECVGSSGIIVPPLIIFKSRHNQAEWY-TDPMLPPDWSITHSPKGWTSDELGLQWLeKIFEPFTRplTVGAYRLLILDGHSSHLTPEFdRACE 212
                 78999****************************.888899******************************************************98899 PP

       DDE_1  97 lqni 100
                 ++n 
  EEA18508.1 213 KSNC 216
                 8886 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.0   1.3e-07   0.00078      27      63 ..       2      38 ..       1      41 [. 0.88
   2 ?   -2.9   0.1       1.2   7.2e+03      56      61 ..     137     142 ..     137     143 .. 0.91

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 1.3e-07
                 HHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT.S-- CS
  HTH_Tnp_Tc5 27 irekAqelaslaadlgepdfkaSkgWldrFkkRh.glk 63
                  re+A+ l+ + +d+++p++k++ +W+d F++R+ +lk
   EEA18508.1  2 AREMANVLLAE-RDKTKPPKKVGINWIDSFLSRNpDLK 38
                 599****9966.8999*****************97776 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.2
                  HHHHTS CS
  HTH_Tnp_Tc5  56 FkkRhg 61 
                  Fk+Rh+
   EEA18508.1 137 FKSRHN 142
                  9****7 PP

>> DDE_3  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0      0.23   1.4e+03       2      51 ..      79     131 ..      78     147 .. 0.68
   2 ?   10.5   0.0   6.4e-05      0.38      64     113 ..     171     222 ..     160     224 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.23
       DDE_3   2 vvfiDEsgfqlgt.vrrrawakkGkr.er.leeygrrgrvnligaldekggla 51 
                 ++ +DE+gf  g    ++     + + +  + + g+r+ v+++  +  +g+++
  EEA18508.1  79 IYNFDETGFAMGIgAIAKVICSSDHQgKPsIIQPGNREWVTVVECVGSSGIIV 131
                 56688998888777777777777776644477888888888777666666555 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 6.4e-05
       DDE_3  64 faeflerlletalqak....kivlilDnasiHkseslrelveeeadrlellylP 113
                   ++le++ e+++++        lilD++s H   ++ ++ e+   ++++ y P
  EEA18508.1 171 GLQWLEKIFEPFTRPLtvgaYRLLILDGHSSHLTPEFDRACEK--SNCWFNYGP 222
                 56899999999999889998999********************..999999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (226 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       247  (0.0137766); expected 358.6 (0.02)
Passed bias filter:                      233  (0.0129957); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1519.14
//
Query:       EEA18509.1  [L=264]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.2e-07   31.6   0.0    2.5e-07   30.5   0.0    1.5  1  DUF4939         Domain of unknown function (DUF4939)
    8.6e-05   22.4   4.1    0.00014   21.8   4.1    1.4  1  zf-CCHC         Zinc knuckle
     0.0068   16.3   3.4      0.016   15.2   3.4    1.7  1  zf-CCHC_3       Zinc knuckle
  ------ inclusion threshold ------
      0.051   13.3   0.3      0.095   12.4   0.3    1.5  1  DUF1489         Protein of unknown function (DUF1489)
      0.087   12.6   1.5       0.18   11.5   1.1    1.6  2  zf-CCHC_5       GAG-polyprotein viral zinc-finger
       0.12   12.2   2.1       0.19   11.6   2.1    1.3  1  zf-CCHC_2       Zinc knuckle
       0.96    9.4   0.0       0.96    9.4   0.0    2.5  3  Pox_A_type_inc  Viral A-type inclusion protein repeat


Domain annotation for each model (and alignments):
>> DUF4939  Domain of unknown function (DUF4939)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.5   0.0   9.9e-11   2.5e-07      22      81 ..      36      95 ..      18     105 .. 0.86

  Alignments for each domain:
  == domain 1  score: 30.5 bits;  conditional E-value: 9.9e-11
     DUF4939 22 wrnpipfpetfdGdtdrlpefivqtlsymlvdektfssdalkvtflitrltGealewvlp 81
                 +   p p+ fdG+   l +f+ q+  ++ ++   +s++  kv+f+ t lt ea +w+ p
  EEA18509.1 36 KQPKTPKPQIFDGKRSELKNFLTQMDMHIAINGASLSTEESKVIFVATCLTREAFQWIEP 95
                34446899*************************************************966 PP

>> zf-CCHC  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   4.1   5.5e-08   0.00014       2      18 .]     224     240 ..     223     240 .. 0.93

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 5.5e-08
                 CTSSSSSSSSTTTTSTS CS
     zf-CCHC   2 kCynCGepGHiardCpk 18 
                  CynC + GH+ar+C++
  EEA18509.1 224 ECYNCYKKGHYARECKS 240
                 6**************85 PP

>> zf-CCHC_3  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   3.4   6.1e-06     0.016       3      26 ..     221     245 ..     219     260 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 6.1e-06
   zf-CCHC_3   3 asaaCQkClkkGHwtYECkn.ager 26 
                  ++ C +C kkGH++ ECk  ++er
  EEA18509.1 221 SNVECYNCYKKGHYARECKSpKQER 245
                 6789***************986666 PP

>> DUF1489  Protein of unknown function (DUF1489)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.3   3.7e-05     0.095      61     123 ..     133     194 ..     107     210 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 3.7e-05
     DUF1489  61 rqrilgleevtdedgikrcalvldpelvrveprpkrpfQGWRYLkaedaPkDlekgeeaelee 123
                   +++++++ +d d+    a+++d++  + + +++r  QGWR   +  +P++ +++++++ + 
  EEA18509.1 133 QMELIKMDRPDDIDEFIEQAVKIDNKFYEMK-QKRREMQGWRKHGTMPTPRNHHRTNQNQRKY 194
                 56889999999999999999******99986.6799**************9998776665433 PP

>> zf-CCHC_5  GAG-polyprotein viral zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       2.9   7.4e+03      25      33 ..      67      75 ..      66      77 .. 0.81
   2 ?   11.5   1.1   7.1e-05      0.18       5      20 ..     225     240 ..     223     244 .. 0.94

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 2.9
                GGEE---XX CS
   zf-CCHC_5 25 nGnpLsane 33
                nG  Ls  e
  EEA18509.1 67 NGASLSTEE 75
                9999*9877 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 7.1e-05
                 -TTT-SSBS-TTT--- CS
   zf-CCHC_5   5 CpRCkkgkHwardChs 20 
                 C  C k  H+ar+C+s
  EEA18509.1 225 CYNCYKKGHYARECKS 240
                 999************9 PP

>> zf-CCHC_2  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   2.1   7.5e-05      0.19       6      19 ..     225     238 ..     224     240 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 7.5e-05
   zf-CCHC_2   6 ChiCgkkGHyIqdC 19 
                 C  C+kkGHy ++C
  EEA18509.1 225 CYNCYKKGHYAREC 238
                 778**********9 PP

>> Pox_A_type_inc  Viral A-type inclusion protein repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.0   0.00037      0.96       5      18 ..      21      34 ..      20      35 .. 0.93
   2 ?   -2.5   1.3       2.3   5.8e+03       2       9 ..     161     168 ..     161     169 .. 0.88
   3 ?   -2.9   0.1       2.9   7.5e+03      14      18 ..     244     248 ..     244     251 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00037
  Pox_A_type_inc  5 rlRsRIsDLErqLs 18
                    rl+ RI +LE qL+
      EEA18509.1 21 RLQARIQELEAQLA 34
                    9************8 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 2.3
  Pox_A_type_inc   2 EmsrlRsR 9  
                     Em ++R++
      EEA18509.1 161 EMKQKRRE 168
                     99999996 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 2.9
  Pox_A_type_inc  14 ErqLs 18 
                     ErqL 
      EEA18509.1 244 ERQLK 248
                     89996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (264 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1484  (0.0827709); expected 358.6 (0.02)
Passed bias filter:                      673  (0.037537); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.50
# Mc/sec: 1588.52
//
Query:       EEA18510.1  [L=1463]
Description: DNA helicase recq, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-11   45.0   0.0    9.7e-11   42.0   0.0    2.4  2  Helicase_C    Helicase conserved C-terminal domain
    7.7e-09   35.6   0.0      3e-08   33.7   0.0    2.0  1  DEAD          DEAD/DEAH box helicase
     0.0014   19.0   3.4     0.0027   18.1   1.3    2.6  2  OrsD          Orsellinic acid/F9775 biosynthesis cluster prot
  ------ inclusion threshold ------
       0.02   14.9   0.0      0.047   13.7   0.0    1.6  1  ResIII        Type III restriction enzyme, res subunit
      0.045   14.5   0.2       0.16   12.7   0.2    2.0  1  RecQ_Zn_bind  RecQ zinc-binding
       0.13   11.5   0.0       0.23   10.7   0.0    1.3  1  Peptidase_S8  Subtilase family


Domain annotation for each model (and alignments):
>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0      0.54   1.6e+03      57      89 ..    1031    1064 ..    1000    1071 .. 0.83
   2 !   42.0   0.0   3.3e-14   9.7e-11      15     110 ..    1076    1175 ..    1063    1176 .. 0.84

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.54
                  HHHHHHH.TTSSSEEEESGGGTSSSTSTTESEEE CS
  Helicase_C   57 eileqfn.kgesdvLiatdvaerGidipkvnlVi 89  
                   ++++f+  ++++v ia +v ++++d+++ ++V 
  EEA18510.1 1031 TVVQRFRsPHTTRVNIAYRVESMSVDVDEDEVVA 1064
                  57899*944555599************9887776 PP

  == domain 2  score: 42.0 bits;  conditional E-value: 3.3e-14
                  TTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHH...TTS.....SS.EEEESGGGTSSSTSTTESEEEESSSSSSHHHHHH CS
  Helicase_C   15 eggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfn...kge.....sd.vLiatdvaerGidipkvnlVinfdlprnvtsyiq 102 
                  +gg+i+++   + ++   + l     + ++++hg++    +e++l++f    +g+     s   ++at+++++Gi+i  v++Vi++++p  +++y q
  EEA18510.1 1076 RGGQIIVYRSETGDV---DAL--ATRLGCLAYHGKMAVAMKEHALQAFTphpEGTtdpirSGmTIVATNALGMGINIRTVRCVIHVEVPSMLREYSQ 1167
                  677888888888888...455..4568999******************96654556666533479******************************** PP

                  HHTTSSST CS
  Helicase_C  103 riGRtgRa 110 
                   +GR+gR 
  EEA18510.1 1168 ESGRAGRD 1175
                  *******6 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.7   0.0   9.9e-12     3e-08       3     173 ..     867    1017 ..     865    1021 .. 0.76

  Alignments for each domain:
  == domain 1  score: 33.7 bits;  conditional E-value: 9.9e-12
                  HHHHHHHHHHTTC.EEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTC CS
                  xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD    3 iQaeaiplilggg.dvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngv 98  
                  iQ++ai++++g    vl+ + TG GK+++f++p+    +e    ++   ++v+ t +L +++ +++ + +      ++ + +  +         +++
  EEA18510.1  867 IQKAAIDAVMGSApWVLGVMGTGGGKSMIFMVPAA---WE----RAGTSIVVVLTVSLRQDMQRECAQAGIS----CVPWNSHRPP--------ETA 944 
                  9*********66559********************...43....45578889999*************9994....2222222222........456 PP

                  SEEEEEHHHHHHHH.....HCTSSHCTTEEEEEEETHHHHHHT..TTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHH CS
                  xxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   99 divvgtpgrlddll.....stgklnlsqvrflVlDEadrlldq..gfsdfinrilnqlpqitcdgklqrqvivlSATlpkdv 173 
                  +iv+ tp+   +       s +  + +++  +V+DE++++ld+  +f++++  ++  +   t   +    v++l+ATlp  v
  EEA18510.1  945 RIVLVTPESATSKGfrsyiS-RLQERNRLDRIVIDECHTILDSreEFRPKMAGLHVLM---TIGSP----VVLLTATLP-AV 1017
                  78999998888844354432.2223788899***********9888888888877777...44445....********9.44 PP

>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   1.3   9.1e-07    0.0027      55     114 .]      21      81 ..       8      81 .. 0.86
   2 ?   -1.9   0.0       1.5   4.5e+03      35      63 ..     467     494 ..     458     508 .. 0.71

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 9.1e-07
        OrsD  55 lrqldelareaeavslpsaesepipgL..pvyeGyrCrakakCkyltrslktlrkHlqkkhg 114
                  +q+ e  r++ ++ +p+++ +pipgL  p    y+C   ++C+++  +++++++H +++hg
  EEA18510.1  21 HQQFPERIRHHRELVIPHKPIAPIPGLipPRDPTYQC-SYPGCHWIGETIRRIHDHCRQEHG 81 
                 56777778999999************96555699***.78*******************995 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 1.5
        OrsD  35 rqlkrektqelletvehemslrqldelar 63 
                  q++r ++ +l+etv h    r +d+l++
  EEA18510.1 467 YQHHRFTMDQLRETV-HGIINRAWDHLTQ 494
                 456666788999999.8888899996644 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   1.6e-05     0.047      30     147 ..     885     986 ..     863    1016 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.6e-05
                 EESTTSTHHHHH.HHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--.......-SEEEEEHHHHHHTH........H CS
      ResIII  30 kmaTGtGKTlva.aklierllkkgkeekflflvprkslleqtleefkkflseaykeigkkvsgdkkkakekdstnkkilvttiqsldadseeeeeesee 127
                 +m TG GK+++  + ++++ +        +++v + sl + +++e ++   +++      +++ +  +      +++i+++t +s++++   +++ s  
  EEA18510.1 885 VMGTGGGKSMIFmVPAAWERAG-----TSIVVVLTVSLRQDMQRECAQAGISCV-----PWNSHRPPE------TARIVLVTPESATSKG-FRSYISRL 966
                 799******9985667777766.....6899999************99999875.....677777777......8999999999999988.56999999 PP

                 HHTTT-SEEEEETGGGTTS. CS
      ResIII 128 llrdrfdviiiDEaHrlgak 147
                 ++r+r d i+iDE+H + ++
  EEA18510.1 967 QERNRLDRIVIDECHTILDS 986
                 9**************98875 PP

>> RecQ_Zn_bind  RecQ zinc-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.2   5.3e-05      0.16      30      65 ..    1207    1245 ..    1190    1246 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 5.3e-05
  RecQ_Zn_bind   30 amlaycentteCrrkllleyFgeeaaeeeC..gn..CDnC 65  
                    am +y + t+ Crr +l  y +  +  + C  g+  CD C
    EEA18510.1 1207 AMREYFHGTR-CRRAVLDAYLDSYERPDGCtdGEapCDQC 1245
                    899***6666.**********98777778*662266**99 PP

>> Peptidase_S8  Subtilase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   7.5e-05      0.23      49      88 ..     760     801 ..     674     810 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 7.5e-05
                   S-TT-SC-SSS......HHHHHHHHHH-B..SSSSSB-SSTT CS
                   xxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8  49 tstnwarddngnsie..HGthvAGiaaanapeegekngvapg 88 
                       w++dd + +i+  HG+hvAG++ a   ee      a +
    EEA18510.1 760 DGCWWTADDAVIDIQagHGSHVAGMIYARGVEEAPGTMAAMK 801
                   34447778877777799**********995555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1463 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       625  (0.0348597); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.95u 0.26s 00:00:01.21 Elapsed: 00:00:00.48
# Mc/sec: 9233.91
//
Query:       EEA18511.1  [L=1564]
Description: DNA helicase recq, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.4e-13   51.0   1.0    1.9e-13   50.6   0.1    1.7  2  DEAD        DEAD/DEAH box helicase
    2.8e-12   46.9   0.1    6.4e-12   45.8   0.1    1.6  1  Helicase_C  Helicase conserved C-terminal domain
      1e-05   25.6   0.0    4.3e-05   23.6   0.0    2.0  2  ResIII      Type III restriction enzyme, res subunit
      0.005   16.6   0.8        2.1    8.0   0.1    3.1  3  AAA_30      AAA domain


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.6   0.1   4.1e-17   1.9e-13       3     174 ..     846     998 ..     844    1000 .. 0.78
   2 ?   -3.8   0.1         2   9.2e+03      37      68 ..    1049    1078 ..    1043    1088 .. 0.69

  Alignments for each domain:
  == domain 1  score: 50.6 bits;  conditional E-value: 4.1e-17
                 HHHHHHHHHHTTC.EEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTCSE CS
                 xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   3 iQaeaiplilggg.dvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngvdi 100
                  Q+++i+ i++ +  +++ ++TG+GK+l f++p+         ++g  +++v+P+ +L  +  +++++++         +++     d ++ +  g+ i
  EEA18511.1 846 TQKAVIQSIVQRQsPIVAIMPTGAGKSLLFMLPAW-------MSRGGTTIVVVPLVALRADLQQRCQTLGIS-------CVE----WDSRRPV-DGASI 925
                 599*******766378899****************.......4677899************99999999984.......233....4555777.8999* PP

                 EEEEHHHHHHHH.....HCTSSHCTTEEEEEEETHHHHHHT..TTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHHH CS
                 xxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD 101 vvgtpgrlddll.....stgklnlsqvrflVlDEadrlldq..gfsdfinrilnqlpqitcdgklqrqvivlSATlpkdvk 174
                 v+ tp+  ++ +     + +k  ++++  +V+DE++ +l++  +f++++ ++ +         +++ q+++l+ATlp++ +
  EEA18511.1 926 VLVTPESAVSETfqtfiN-RKQWTKELDRIVIDECHIILQEgyQFRKQMAQLGAL-------VRAETQLVLLTATLPRESE 998
                 *****9999966465533.343599****************44444555553333.......345567*********8765 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 2
                  HHHHHSTTSTS-EEEEEESSHHHHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   37 qivyetkgktgpkalivePtreLaeqtlnnlk 68  
                  q+ +  ++ ++ k++i + t + ++q++++l+
  EEA18511.1 1049 QQRV--QQLHEGKVVIYANTIATVQQIAHQLQ 1078
                  3333..36667789999999999999988876 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.8   0.1   1.4e-15   6.4e-12      12     110 ..    1053    1144 ..    1043    1145 .. 0.89

  Alignments for each domain:
  == domain 1  score: 45.8 bits;  conditional E-value: 1.4e-15
                  HTTTTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSSHHHHHHHHTTSS CS
  Helicase_C   12 leeeggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprnvtsyiqriGRtg 108 
                  ++ ++gk++i++nti ++   + +   +++++ ++++  ++ +++ +l++f+k++  v++at+++++Gidip+++lVi+++  r++ +y q +GR+ 
  EEA18511.1 1053 QQLHEGKVVIYANTIATV---QQI--AHQLQCPAYYS--QAVDKKGMLASFRKQNPGVIVATSALGMGIDIPDIRLVIHVGRTRSLLDYGQESGRAR 1142
                  56689*************...566..46789999999..8999********998888***************************************9 PP

                  ST CS
  Helicase_C  109 Ra 110 
                  R 
  EEA18511.1 1143 RD 1144
                  85 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.6   0.0   9.6e-09   4.3e-05       7     170 ..     846     994 ..     814     995 .. 0.79
   2 ?   -1.7   0.0      0.56   2.5e+03      41      76 ..    1044    1079 ..    1042    1104 .. 0.79

  Alignments for each domain:
  == domain 1  score: 23.6 bits;  conditional E-value: 9.6e-09
                 HHHHHHHHHT......TTSEEEEEESTTSTHHHHHHHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--.......-S CS
      ResIII   7 yQeeaienlleklkskrdkrglikmaTGtGKTlvaaklierllkkgkeekflflvprkslleqtleefkkflseaykeigkkvsgdkkkakekdstnkk 105
                  Q+ +i++++     +r+  ++  m+TG+GK+l+ +  ++  +       ++++vp  +l   ++++ + +  +++     ++++++          ++
  EEA18511.1 846 TQKAVIQSIV-----QRQSPIVAIMPTGAGKSLLFMLPAWMSRGG----TTIVVVPLVALRADLQQRCQTLGISCV-----EWDSRRPVD------GAS 924
                 4555555554.....8999**************999999988875....89*********************9874.....666666666......889 PP

                 EEEEEHHHHHHTH........HHHTTT-SEEEEETGGGTTS......TTTHHHHHT-.--SEEEEEESS-S CS
      ResIII 106 ilvttiqsldadseeeeeeseellrdrfdviiiDEaHrlgak.....kswreilekf.keavllglTATpe 170
                 i+++t +s+ ++   ++  + ++  ++ d i+iDE+H + ++     k++ ++   +  e  l+ lTAT++
  EEA18511.1 925 IVLVTPESAVSET-FQTFINRKQWTKELDRIVIDECHIILQEgyqfrKQMAQLGALVrAETQLVLLTATLP 994
                 9999999988888.4456666667777779*******9999655555566666333324477778899986 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.56
                  HHHHHHHH-S.....-EEEEESSHHHHHHHHHHGGG CS
      ResIII   41 aaklierllkkgkeekflflvprkslleqtleefkk 76  
                  ++  i++  ++ +e k+++ +++++ ++q  +++++
  EEA18511.1 1044 MITWIQQRVQQLHEGKVVIYANTIATVQQIAHQLQC 1079
                  7778888899999999***99999999999877765 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.6   0.0    0.0052        23     155     187 ..      52      84 ..      49      87 .. 0.94
   2 !    8.0   0.1   0.00047       2.1       3     114 ..     844     982 ..     842     990 .. 0.69
   3 ?   -0.1   0.0      0.15   6.7e+02      38      71 ..    1048    1082 ..    1041    1103 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.0052
      AAA_30 155 vRqkeseeraaalalregdaeealealadrgri 187
                 +Rq  + e++aa+++++g+++ea  +l++ g++
  EEA18511.1  52 HRQYAEYEKQAAERIQQGHIDEANPWLRRTGWV 84 
                 8**99***********************99998 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.00047
      AAA_30   3 naeQaaavealltsgdrvavltGpAGtGKttalkalreaweaaggrviglAptgkaAkvLaeelgieastiakllkrlk.................... 81 
                 +  Q+a+++++++ +    v+  p G+GK+ +   +  aw ++gg+ i++ p  +  ++L++ +++ + +  ++ +r                      
  EEA18511.1 844 RGTQKAVIQSIVQRQS-PIVAIMPTGAGKSLLF--MLPAWMSRGGTTIVVVPLVALRADLQQRCQTLGISCVEWDSRRPvdgasivlvtpesavsetfq 939
                 568********99997.7777789*****9887..4578999998999888888888888865554333333333332355566666666666777777 PP

      AAA_30  82 ...grarlepg.tllivDEagmv......dtkqlaallkaaek 114
                    +r++++++ + +++DE   +        kq+a+l + +++
  EEA18511.1 940 tfiNRKQWTKElDRIVIDECHIIlqegyqFRKQMAQLGALVRA 982
                 778778899999*******987755554444566666666655 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.15
      AAA_30   38 lreaweaa.ggrviglAptgkaAkvLaeelgieas 71  
                  +++ +++  +g+v+++A t +  +++a++l+ +a+
  EEA18511.1 1048 IQQRVQQLhEGKVVIYANTIATVQQIAHQLQCPAY 1082
                  555556665799***************99998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1564 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       815  (0.0454571); expected 358.6 (0.02)
Passed bias filter:                      553  (0.0308439); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.01u 0.28s 00:00:01.29 Elapsed: 00:00:00.47
# Mc/sec: 10037.54
//
Query:       EEA18512.1  [L=178]
Description: hypothetical protein PMAA_007910 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    0.00071   20.2   0.9    0.00074   20.2   0.1    1.5  2  Abhydrolase_6  Alpha/beta hydrolase family
     0.0017   17.9   0.0     0.0023   17.4   0.0    1.2  1  DUF676         Putative serine esterase (DUF676)
  ------ inclusion threshold ------
      0.043   13.1   0.0       0.39   10.0   0.0    2.0  2  Hydrolase_4    Serine aminopeptidase, S33
      0.045   13.4   0.1       0.12   12.0   0.1    1.7  1  Abhydrolase_1  alpha/beta hydrolase fold
      0.049   13.3   0.0      0.086   12.6   0.0    1.5  1  PGAP1          PGAP1-like protein
      0.086   12.7   0.0       0.11   12.3   0.0    1.1  1  Palm_thioest   Palmitoyl protein thioesterase
       0.19   11.2   0.0       0.26   10.8   0.0    1.1  1  DUF900         Alpha/beta hydrolase of unknown function (DUF9


Domain annotation for each model (and alignments):
>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.1       2.2   5.6e+03     108     108 ..      36      36 ..       3      60 .. 0.46
   2 !   20.2   0.1   2.9e-07   0.00074       1      79 [.      64     156 ..      64     178 .] 0.64

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 2.2
                    - CS
  Abhydrolase_6 108 a 108
                    +
     EEA18512.1  36 R 36 
                    1 PP

  == domain 2  score: 20.2 bits;  conditional E-value: 2.9e-07
                    EEEE--GC......G..C..HHHHHHHHCCT.....CEEEEE--TTSTS-GGCS....--HHH..CHHH..HHHHCCTT..TTSEEEEEETCHHHH CS
  Abhydrolase_6   1 vlllHGagss.assW..l..vapLaallaag.....vhvlapDlpGhGrsdppp....ldled..ladl..aalldelaagggpvvlvGHSlGGal 78 
                    ++ +HG+ ++    W  +  v  L +ll+ +     v ++ +D+  h   d+      +d++   + dl  ++ l+      +p++ v+HSlGG++
     EEA18512.1  64 IVAVHGLNGHrDKTWtaAngVNWLSNLLPTDipnarVFCWGYDANTHD--DRVScqylYDHATqlVSDLclERRLTNT--TQRPIIFVAHSLGGII 155
                    7899**55444888864245667788888887777778899***9994..4444444433322434555553333333..37889*********95 PP

                    H CS
  Abhydrolase_6  79 a 79 
                    +
     EEA18512.1 156 V 156
                    4 PP

>> DUF676  Putative serine esterase (DUF676)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.0   9.2e-07    0.0023       7      95 ..      63     158 ..      57     164 .. 0.76

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 9.2e-07
      DUF676   7 LvVlvHGlqgn.......saDlelikeqlekikeklpeekieflmsennesktfkgidvlgerlaeevlevvkkkkdk...nkkiSfvghSlGgliara 95 
                  +V vHGl+g         +  + + + l    +++p+ ++   ++ +n  +     ++l +   + v +   +++ +   +  i fv+hSlGg+i+++
  EEA18512.1  63 SIVAVHGLNGHrdktwtaANGVNWLSNLL---PTDIPNARVFCWGYDANTHDDRVSCQYLYDHATQLVSDLCLERRLTnttQRPIIFVAHSLGGIIVKS 158
                 5899******9633333222223333333...45899999*********99999999999999999999888777766676667************986 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.0     0.079     2e+02       4      19 ..      61      76 ..      58      85 .. 0.79
   2 ?   10.0   0.0   0.00015      0.39      55      92 ..     123     158 ..     102     166 .. 0.76

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.079
  Hydrolase_4  4 kavvvlvHGlaehsgr 19
                    +v vHGl+ h ++
   EEA18512.1 61 SRSIVAVHGLNGHRDK 76
                 5689*******99776 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00015
  Hydrolase_4  55 fddyvdDlaafvekvkeehpelplfllGhSmGGliall 92 
                   +++v Dl   +e+  ++  ++p++ ++hS+GG+i+ +
   EEA18512.1 123 ATQLVSDL--CLERRLTNTTQRPIIFVAHSLGGIIVKS 158
                  45556665..345555677788*************965 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.1   4.8e-05      0.12       2      87 ..      63     156 ..      62     158 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 4.8e-05
                    EEEEE-STTT.........CGGGGTTGHHHHHHHHTTSEEEEEEETTSTTSSSTTTGB...CHHSHHHHHHHHHHHHHHCTTSSEEEEEETHHHHH CS
  Abhydrolase_1   2 vlvilhGlpg.........ssdvwaerglapaLakdgfdvillDlrGvgySspapacin..ddygtasvaddldrildalgddkltlvGhSmGGmi 86 
                    ++v +hGl g         ++ +w  ++l+ +++ ++ +++++D   + + ++ +++    d+ +      +l+r l  + +++++ v+hS+GG i
     EEA18512.1  63 SIVAVHGLNGhrdktwtaaNGVNWLSNLLPTDIPNARVFCWGYDA--NTHDDRVSCQ-YlyDHATQLVSDLCLERRLTNTTQRPIIFVAHSLGGII 155
                    6899******6666666666666***********99999999996..7777777776.2243334433333444669999999999********88 PP

                    H CS
  Abhydrolase_1  87 a 87 
                    +
     EEA18512.1 156 V 156
                    5 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   3.3e-05     0.086      51     108 ..     105     159 ..      50     164 .. 0.61

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 3.3e-05
       PGAP1  51 vdfneelsaldGrtlldqaeyln.d.aIkyIlslysssekeptsviliGHSmGGivaraa 108
                 +d n     +  ++l d+a  l  d ++++     + +++ ++ +i ++HS+GGi+ +++
  EEA18512.1 105 YDANTHDDRVSCQYLYDHATQLVsDlCLER-----RLTNTTQRPIIFVAHSLGGIIVKSV 159
                 444544455555677777654431213333.....345889999***********98876 PP

>> Palm_thioest  Palmitoyl protein thioesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   4.4e-05      0.11       2      81 ..      64     157 ..      63     164 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 4.4e-05
  Palm_thioest   2 vviwhGl....dsaesn.......mqklaeliekli.gtyvknveigeseaedrkas..ffgnlndqveavckk....lelangfhaiGfSQGglfl 80 
                   +v +hGl    d    +       ++ l +l+ ++i ++ v +   +++  +dr ++  ++ ++++ v++ c +    +++++ ++++++S Gg+++
    EEA18512.1  64 IVAVHGLnghrD----KtwtaangVNWLSNLLPTDIpNARVFCWGYDANTHDDRVSCqyLYDHATQLVSDLCLErrltNTTQRPIIFVAHSLGGIIV 156
                   8999***75432....2356566788888888888855888888888887777766532567788888888888899977899************98 PP

  Palm_thioest  81 R 81 
                    
    EEA18512.1 157 K 157
                   6 PP

>> DUF900  Alpha/beta hydrolase of unknown function (DUF900)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0    0.0001      0.26      20     109 ..      62     157 ..      49     162 .. 0.68

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.0001
      DUF900  20 eilvfvhGynnsFedavlraaqiaddlk...nqg.aivvfsWPsagklld......ynyDresaeasrdalekllrylatkksakkihllaHSmGtwlv 108
                 + +v vhG n + ++  + a  +   ++    +  ++ vf W   +++ d      y yD ++   s   le+ l+   ++  ++ i  +aHS G  +v
  EEA18512.1  62 RSIVAVHGLNGHRDKTWTAANGVNWLSNllpTDIpNARVFCWGYDANTHDdrvscqYLYDHATQLVSDLCLERRLT---NT-TQRPIIFVAHSLGGIIV 156
                 45677888776655544433333222222224445566899*9999998888888899999999999988886554...44.5668999******9988 PP

      DUF900 109 l 109
                  
  EEA18512.1 157 K 157
                 5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (178 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       393  (0.0219198); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 1241.83
//
Query:       EEA18513.1  [L=309]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.9e-12   46.6   0.0    1.6e-11   44.6   0.0    1.8  1  APH              Phosphotransferase enzyme family
    3.2e-06   26.9   0.0    6.7e-06   25.8   0.0    1.5  1  Choline_kinase   Choline/ethanolamine kinase
    0.00023   20.2   0.0       0.35    9.7   0.0    2.1  2  DUF1679          Protein of unknown function (DUF1679)
    0.00073   18.8   0.0      0.068   12.4   0.0    2.1  2  Fructosamin_kin  Fructosamine kinase
     0.0017   17.8   0.0       0.99    8.7   0.0    2.2  2  Pkinase          Protein kinase domain
     0.0018   17.6   0.0     0.0037   16.6   0.0    1.5  2  EcKinase         Ecdysteroid kinase
  ------ inclusion threshold ------
       0.19   11.0   0.0       0.41    9.9   0.0    1.4  1  Pkinase_Tyr      Protein tyrosine kinase


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.6   0.0   6.1e-15   1.6e-11      40     228 ..     105     293 ..     101     299 .. 0.70

  Alignments for each domain:
  == domain 1  score: 44.6 bits;  conditional E-value: 6.1e-15
                 HHHHHHHHHHTT-.B--B-CTTBS-EEETTEEEEEEE----EE-SS...HHHHHHHHHHHHHHHHHHCCHHCH..-STTTB-SHHCHTCCHHHHHHCHH CS
         APH  40 evallrlLakagv.pvPevlagdtddeeigllfalieyvpgrsllr...klsaaqlpellealgeflaalhqvd.paalpladflaqdlellrqlesat 133
                 e++ +++La++ + pvP+v+a   d + + + + ++ey+pg++l+     l++ ++  +   + +++ +l     p  ++++        +l+ +e+  
  EEA18513.1 105 EAENMKFLAANSKvPVPKVHAAFRDPDTNKT-YIIMEYLPGHTLEKllpSLDPVEKATISNLIKDAITELRKGLdPKISGPFANQ--GDMNLAIIEKI- 199
                 78899999966666******86666666664.9***************9666666666666666666666666446655555444..23344444444. PP

                 HCCCGCCTCCHHHHHHHHHHHHHHHH--SSS-EEEE-SS-SGGGEEEC..........TTEEEEE---TT-EEEECCHHH...HCCHHHCSCHCCCHCH CS
         APH 134 arllaselldlleeleeqvlaalaallpgelptvllHgDlhpgNllvd........pddgrvtGviDfedaglgpplyDl...avllrswtseldpefl 221
                  r  + e ++    ++  ++++++++l +  + v++HgDl p N++v+        p+  r+  ++D+e ag+ p l+D+    +++     + + e++
  EEA18513.1 200 -R--QTESDQ---YIRL-LRNMIDRTLNS-HRSVFTHGDLQPKNIMVErfgdrnvcPQ-FRI-SLLDWESAGWYPELWDFcnaTIAC--RFKPDWLELV 286
                 .2..224444...4455.55888888885.99*****************976666444.565.9****************4433333..2466666666 PP

                 HHHHHHH CS
         APH 222 aallray 228
                  ++l++y
  EEA18513.1 287 PDILEQY 293
                 6666666 PP

>> Choline_kinase  Choline/ethanolamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   0.0   2.6e-09   6.7e-06     118     186 ..     195     272 ..     180     282 .. 0.85

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 2.6e-09
                     CHCCCTHHHHHHHHHTHHHHH.HCHGG-.EEEE-S--SGGGEEE........-CTTEEEE--GTT-EEEEHHHHHHHH CS
  Choline_kinase 118 qlklinledlekeleklekll.eelesp.vvfcHnDlqegNill.......nkeekklvlIDFEYagynyrgfDlanh 186
                      +++i+ ++ ++ +  l++++   l+s+  vf H Dlq++Ni++          + ++ l D+E ag  +  +D++n 
      EEA18513.1 195 IIEKIRQTESDQYIRLLRNMIdRTLNSHrSVFTHGDLQPKNIMVerfgdrnVCPQFRISLLDWESAGWYPELWDFCNA 272
                     5789999999999999*****444454479**************9999887677899******************996 PP

>> DUF1679  Protein of unknown function (DUF1679)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   0.0   0.00014      0.35     128     166 ..     115     151 ..     104     176 .. 0.77
   2 !    8.6   0.0   0.00029      0.73     259     336 ..     214     295 ..     181     305 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00014
     DUF1679 128 heeilltkvyflkkfdeenklkgyiimeyvedihtlsmy 166
                 +++++++kv++   f + +++k yiimey+++ +  +++
  EEA18513.1 115 NSKVPVPKVHA--AFRDPDTNKTYIIMEYLPGHTLEKLL 151
                 57899999986..7*****************98765554 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.00029
     DUF1679 259 kvskvlGi.kkvlvhgDlwsaNiLfseeeegklklk...kviDyQlvslgnpaeDlvrlllscLsgedRrarkeelLeqyye 336
                  ++++l   + v++hgDl   Ni+ ++ ++ +++ +    ++D+  +   +   D     ++c  + d  +   ++Leqy  
  EEA18513.1 214 MIDRTLNShRSVFTHGDLQPKNIMVERFGDRNVCPQfriSLLDWESAGWYPELWDFCNATIACRFKPDWLELVPDILEQYPV 295
                 45666665599****************9998887553346889999988888888888888888888888888888888855 PP

>> Fructosamin_kin  Fructosamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.4   0.0   2.6e-05     0.068      58      97 ..     104     145 ..      65     151 .. 0.82
   2 !    4.4   0.0    0.0073        19     164     207 ..     202     243 ..     187     250 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2.6e-05
  Fructosamin_kin  58 aEaesLealaetqtirvPkvlavGel..kdasfLvleyLelk 97 
                       Eae+++ la+ +++ vPkv+a+     ++++++++eyL+ +
       EEA18513.1 104 IEAENMKFLAANSKVPVPKVHAAFRDpdTNKTYIIMEYLPGH 145
                      59******************998654227888*******976 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.0073
  Fructosamin_kin 164 glefakieelvervaellskhqpkpsllHGdLWsgNaaltkdge 207
                        +++ i+ l ++++++l++h+   +  HGdL   N+++++ g+
       EEA18513.1 202 TESDQYIRLLRNMIDRTLNSHR--SVFTHGDLQPKNIMVERFGD 243
                      2336666777777888887775..6899*********9999875 PP

>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.1   0.0    0.0012       3.1      64     106 ..     124     168 ..      88     178 .. 0.76
   2 !    8.7   0.0   0.00039      0.99      95     142 ..     202     257 ..     183     270 .. 0.64

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0012
                 EEEEEE..SSEEEEEEE--TTEBHHHHHHHHSS--HHHHHHHHHH CS
     Pkinase  64 yevfee..kdelylvleyveggeladllerkgslseeeakkiakq 106
                   +f++  +++ y+++ey++g +l++ll     ++++++++++k 
  EEA18513.1 124 HAAFRDpdTNKTYIIMEYLPGHTLEKLLPSLDPVEKATISNLIKD 168
                 556666447899****************96556666666555543 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.00039
                 --HHHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTE........EEE-SG CS
     Pkinase  95 lseeeakkiakqilegleylHskgiiHrDlKpeNiLidekge........lKitDF 142
                  ++++  +++++++      H+  + H Dl p+Ni++++ g+        + + D+
  EEA18513.1 202 TESDQYIRLLRNMIDRTLNSHRSVFTHGDLQPKNIMVERFGDrnvcpqfrISLLDW 257
                 444444455555554444569999*************9655444555544555555 PP

>> EcKinase  Ecdysteroid kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0      0.98   2.5e+03      77      98 ..     119     142 ..     108     148 .. 0.76
   2 !   16.6   0.0   1.5e-06    0.0037     189     281 ..     195     293 ..     138     300 .. 0.66

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.98
    EcKinase  77 lapkcykaeeeee..eevlvleDL 98 
                  +pk++ a ++++  ++++++e L
  EEA18513.1 119 PVPKVHAAFRDPDtnKTYIIMEYL 142
                 567777777777766899999988 PP

  == domain 2  score: 16.6 bits;  conditional E-value: 1.5e-06
    EcKinase 189 a.ekleklke.nlferllelve.ekeeefnvlnHGDlwvnNimfkydeeg..epe.dvilvDFQlsrygSpalDLlyflytsteeelrkekfdellriY 281
                   ek+++ ++ ++++ l+++++ + +++ +v++HGDl  +Nim++   +    p+ ++ l+D+  + + +   D +   + +  +    e + ++l++Y
  EEA18513.1 195 IiEKIRQTESdQYIRLLRNMIDrTLNSHRSVFTHGDLQPKNIMVERFGDRnvCPQfRISLLDWESAGWYPELWDFCNATIACRFKPDWLELVPDILEQY 293
                 14666666554888888888887888999**************97543332444446888999888888888887766666655555555666666555 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0   0.00016      0.41      55     138 ..     112     240 ..     103     248 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00016
                  HHTS-BTTB--EEEEEE..SSSSEEEEEE--TTEBHHHHHHHT...........................................CTTTSBHHHHHH CS
  Pkinase_Tyr  55 mkklkhpnivkllgvct..keepllivteyvkgGdLlkfLrkk...........................................ekekltlkdlls 107
                  + + ++  + k++++    ++++++i++ey++g +L+k L +                                            + ++++ ++ ++
   EEA18513.1 112 LAANSKVPVPKVHAAFRdpDTNKTYIIMEYLPGHTLEKLLPSLdpvekatisnlikdaitelrkgldpkisgpfanqgdmnlaiieKIRQTESDQYIR 209
                  444445556677777776667789****************99999999****************************9999999998777888888888 PP

                  HHHHHHHHHHHHHHTTEEEST-SGGGEEEEE CS
  Pkinase_Tyr 108 falqvAkGmeyLeskklvHrdlaarNvLlse 138
                  +  ++ +     ++  + H dl  +N+++++
   EEA18513.1 210 LLRNMIDRTLNSHRSVFTHGDLQPKNIMVER 240
                  888888877777788899*********9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       562  (0.0313459); expected 358.6 (0.02)
Passed bias filter:                      530  (0.029561); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.54u 0.30s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 2030.34
//
Query:       EEA18514.1  [L=271]
Description: hypothetical protein PMAA_007930 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00021   21.8   0.2      0.049   14.2   0.0    3.1  3  Ank_4     Ankyrin repeats (many copies)
    0.00062   20.3   0.0     0.0066   17.0   0.0    2.4  2  Ank_2     Ankyrin repeats (3 copies)
     0.0075   16.7   0.3       0.43   11.1   0.2    2.9  3  Ank       Ankyrin repeat
  ------ inclusion threshold ------
       0.11   13.1   0.1        2.9    8.8   0.1    2.8  2  Ank_3     Ankyrin repeat


Domain annotation for each model (and alignments):
>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.018        83      32      52 ..      97     117 ..      70     120 .. 0.85
   2 !   14.2   0.0   1.1e-05     0.049      29      52 ..     143     165 ..     134     167 .. 0.88
   3 ?   -1.3   0.0      0.84   3.7e+03      24      40 ..     216     232 ..     205     235 .. 0.66

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.018
       Ank_4  32 nrsGetalhiAakrgnveilk 52 
                 +  G++ +h+Aa+ gn ++l 
  EEA18514.1  97 PVTGDSVVHRAASVGNTQFLS 117
                 556999*******99999875 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 1.1e-05
       Ank_4  29 aqdnrsGetalhiAakrgnveilk 52 
                 +q n  G+talh Aa++g+++ +k
  EEA18514.1 143 HQ-NLAGDTALHAAARHGSLQGAK 165
                 67.999*************98776 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.84
       Ank_4  24 gadinaqdnrsGetalh 40 
                 g d  a + +sG++al+
  EEA18514.1 216 GLDAAALAQESGNNALI 232
                 55555566677777775 PP

>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0   1.5e-06    0.0066      25      71 ..      99     166 ..      66     178 .. 0.72
   2 ?   -0.0   0.0      0.31   1.4e+03      22      45 ..     212     235 ..     199     250 .. 0.67

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 1.5e-06
       Ank_2  25 ngktaLhyAakngnleivklLleh.....................adndgrtpLhyAarsghleivkl 71 
                 +g +++h Aa+ gn+++++ Ll                       ++  g t+Lh+Aar+g+l+ +k 
  EEA18514.1  99 TGDSVVHRAASVGNTQFLSGLLGCwgrrcgndkkplgsfwvlmthQNLAGDTALHAAARHGSLQGAKA 166
                 7899999999999999999999744434443444555555544333344***********99888874 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 0.31
       Ank_2  22 pnkngktaLhyAakngnleivklL 45 
                  nk+g+ a  +A ++gn+ ++k++
  EEA18514.1 212 KNKDGLDAAALAQESGNNALIKWF 235
                 334677777777777776667665 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0      0.87   3.9e+03       6      11 ..      72      77 ..      71      87 .. 0.77
   2 ?    2.0   0.0     0.075   3.3e+02       2      22 ..     100     120 ..      99     127 .. 0.82
   3 !   11.1   0.2   9.6e-05      0.43       2      15 ..     148     164 ..     147     178 .. 0.70

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.87
                HHHHHH CS
         Ank  6 LHlAat 11
                LH Aat
  EEA18514.1 72 LHSAAT 77
                9**995 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.075
                 SBBHHHHHHHHTTHHHHHHHH CS
         Ank   2 GnTPLHlAatngkkriiklLL 22 
                 G+++ H+Aa+ g+++ ++ LL
  EEA18514.1 100 GDSVVHRAASVGNTQFLSGLL 120
                 88899****999999888555 PP

  == domain 3  score: 11.1 bits;  conditional E-value: 9.6e-05
                 SBBHHHHHHHHTT...H CS
         Ank   2 GnTPLHlAatngk...k 15 
                 G+T+LH Aa+ g+   +
  EEA18514.1 148 GDTALHAAARHGSlqgA 164
                 9********99985552 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0      0.22     1e+03       2      17 ..     100     115 ..      99     123 .. 0.80
   2 ?    8.8   0.1   0.00064       2.9       2      16 ..     148     162 ..     147     175 .. 0.76

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.22
       Ank_3   2 GetpLhlAarsgnlei 17 
                 G +  h+Aa+ gn+  
  EEA18514.1 100 GDSVVHRAASVGNTQF 115
                 77889******99865 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.00064
       Ank_3   2 GetpLhlAarsgnle 16 
                 G t+Lh Aar+g+l 
  EEA18514.1 148 GDTALHAAARHGSLQ 162
                 89**********985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (271 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       306  (0.0170673); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.47
# Mc/sec: 1738.33
//
Query:       EEA18515.1  [L=368]
Description: hypothetical protein PMAA_007940 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (368 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       380  (0.0211947); expected 358.6 (0.02)
Passed bias filter:                      360  (0.0200792); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 2513.03
//
Query:       EEA18516.1  [L=580]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0044   16.5   0.0     0.0093   15.5   0.0    1.5  1  RVT_1     Reverse transcriptase (RNA-dependent DNA polymerase
     0.0096   16.6   0.1      0.033   14.9   0.1    1.9  1  zf-RVT    zinc-binding in reverse transcriptase


Domain annotation for each model (and alignments):
>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0     1e-06    0.0093     164     221 ..      18      99 ..       3     100 .. 0.91

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1e-06
                 EECTTEEEEEESSHHH......HHHHHHHHHHHHHHTT--BEGGG-EEE.......................ESSEEETTEE CS
       RVT_1 164 lrYaDDililskskee......lqelleaveewlkesglkinpeKtklvlft.................v.kseevkyLGvt 221
                 ++++DD +  ++++++      +q++++   +w ++sg +++ +Kt +v+ft                 v  +++ k+LGv 
  EEA18516.1  18 IAFVDDYTAWVTGPTAesnrsgIQAIINRALDWERRSGATFEGQKTAIVHFTrntdrssstpfvikgklVkPKDSAKILGVV 99 
                 79***********99999***************************************9999999998864799999999985 PP

>> zf-RVT  zinc-binding in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.1   3.7e-06     0.033      53      80 ..     418     445 ..     403     448 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 3.7e-06
      zf-RVT  53 rgiesssrCqlCgqeeEtieHlfleCpf 80 
                 r  +++s  + Cgq+ Et+eH +++C++
  EEA18516.1 418 RIGAVDSDLCACGQASETVEHFLFRCTK 445
                 44445777789***************75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (580 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       553  (0.0308439); expected 358.6 (0.02)
Passed bias filter:                      414  (0.0230911); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.25s 00:00:00.82 Elapsed: 00:00:00.42
# Mc/sec: 4165.51
//
Query:       EEA18517.1  [L=1115]
Description: glucan 1,3-beta-glucosidase precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.3e-84  282.6  19.4    1.9e-75  253.4   8.1    2.9  3  Pectate_lyase_3  Pectate lyase superfamily protein
  ------ inclusion threshold ------
      0.032   13.9   1.0       0.38   10.5   0.3    2.6  2  End_N_terminal   N terminal extension of bacteriophage endosi


Domain annotation for each model (and alignments):
>> Pectate_lyase_3  Pectate lyase superfamily protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  253.4   8.1   2.2e-79   1.9e-75       1     213 [.      71     311 ..      71     313 .. 0.94
   2 ?   -2.5   0.2      0.42   3.7e+03     157     192 ..     329     368 ..     317     392 .. 0.61
   3 !   36.8   0.3   3.9e-13   3.5e-09       4      66 ..     444     500 ..     441     536 .. 0.87

  Alignments for each domain:
  == domain 1  score: 253.4 bits;  conditional E-value: 2.2e-79
                      SEEGGGGT---EEEEE-HHHHHHHH.....................HTSS-EEE-SEEEEESS-EEE-SSEEEEES-TTTEEEEE-TT-SS--S CS
  Pectate_lyase_3   1 frnVkdyGakgDGvtDdtaaiqkais...............casatttgavVYfPaGtYlvsspiilksgvqLvGdgngrpvlkaaaafvgagl 79 
                      frnVkd+Ga+gDGv Ddtaai++a +               c s+tt gavVYfPaGtYl+s+pii+++++q++G+++++pv++++ +f+g +l
       EEA18517.1  71 FRNVKDFGAVGDGVMDDTAAINRAAAsfssaeldtlrcganCGSTTTLGAVVYFPAGTYLISTPIIQYYYTQFIGNPTNKPVIEGSFNFTGIAL 164
                      8************************99******************************************************************* PP

                      EEES-TTT-....-EEEEEEEEEEEGGGG-SS---S.......SEEE....ES-EEEEEEEEEEES-SSEEE-SSS...---TT---SS--EEE CS
  Pectate_lyase_3  80 idgdpyvsg..gsealiatnnfyrqirnlkiditav.......apga....tgihwqtaqatslenvefemseasg...tkhqgifiengsggf 157
                      +d+d y  g  g+e++i++nnfyrqirn+++++t++       +       tgihwq++qats++n++f ms ++     +++gi++engsgg 
       EEA18517.1 165 FDSDFYIPGgnGAEWYINQNNFYRQIRNFQFKMTGMnwtntdnD--QsyvpTGIHWQVGQATSITNCDFVMSVSTAserATGVGIYMENGSGGL 256
                      *******553577***********************98866543..156********************77766655589999*********** PP

                      EES-EEES-SS-SEEES-EEEEEES-EEE-S--SEEE-TT-EEEEEEEEEESSSEE CS
  Pectate_lyase_3 158 lndlvfsglgdigiavgnqqftvrnitfnnattgievlwgwgwtlknvkinncegG 213
                      ++dl+f+g g+ig+  g+qqft++n++f+++ t+i+  w+wg+t+kn+++ +c+  
       EEA18517.1 257 VSDLTFTG-GNIGFLAGSQQFTAKNLQFTSCLTAIYSVWNWGFTWKNINVLSCYIA 311
                      ********.********************************************975 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.42
                      EEES-EEES-SS-SEEE.S....-EEEEEES-EEE-S--SE CS
  Pectate_lyase_3 157 flndlvfsglgdigiav.g....nqqftvrnitfnnattgi 192
                      ++ d++f+g   ++i+v +    + ++++ n+ ++n+  ++
       EEA18517.1 329 TVLDSTFNG-VPYAITVdTkgneQPNIVLDNLLVQNSASVV 368
                      336777777.6666666336665556666777777655544 PP

  == domain 3  score: 36.8 bits;  conditional E-value: 3.9e-13
                      GGGGT---EEEEE-HHHHHHHH......HTSS-EEE-SEEEEESS-EEE-SSEEEEES-TTTE CS
  Pectate_lyase_3   4 VkdyGakgDGvtDdtaaiqkaiscasatttgavVYfPaGtYlvsspiilksgvqLvGdgngrp 66 
                      ++d G+++DG  D++  i++ +    +++ g+v++fPaG Y+vss+++ + g ++vG g   +
       EEA18517.1 444 ATDHGVSNDGTGDQSSSINSLL----SSNVGSVIFFPAGVYMVSSTVKVPVGSVIVGSG--WS 500
                      49********************....999*****************************9..23 PP

>> End_N_terminal  N terminal extension of bacteriophage endosialidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.3   4.2e-05      0.38       1      19 [.      79      97 ..      79     105 .. 0.86
   2 ?    1.0   0.0      0.04   3.6e+02       4      26 ..     452     473 ..     449     488 .. 0.73

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 4.2e-05
                    ---EEEEE-HHHHHHHHHH CS
  End_N_terminal  1 akGDGvtdDtdalsevlaa 19
                    a+GDGv dDt+a++ + a+
      EEA18517.1 79 AVGDGVMDDTAAINRAAAS 97
                    89************99776 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.04
                     EEEEE-HHHHHHHHHHS-TTS-E CS
  End_N_terminal   4 DGvtdDtdalsevlaaapvgkki 26 
                     DG  d  ++++++l++  vg  i
      EEA18517.1 452 DGTGDQSSSINSLLSS-NVGSVI 473
                     9999999******998.555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1115 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       456  (0.0254337); expected 358.6 (0.02)
Passed bias filter:                      206  (0.0114898); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.26s 00:00:00.90 Elapsed: 00:00:00.40
# Mc/sec: 8419.23
//
Query:       EEA18518.1  [L=378]
Description: hypothetical protein PMAA_007970 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (378 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       958  (0.053433); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.48
# Mc/sec: 2380.02
//
Query:       EEA18519.1  [L=257]
Description: hypothetical protein PMAA_007980 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.6e-06   25.9   5.4    7.7e-06   25.8   3.6    2.0  1  zf-RING_UBOX  RING-type zinc-finger
    1.9e-05   24.4   8.7      3e-05   23.8   8.7    1.3  1  zf-C3HC4_3    Zinc finger, C3HC4 type (RING finger)
    8.9e-05   22.3   5.4    0.00011   21.9   4.5    1.8  1  zf-C3HC4      Zinc finger, C3HC4 type (RING finger)
     0.0034   17.3   9.5      0.007   16.3   9.5    1.6  1  zf-RING_5     zinc-RING finger domain
     0.0037   17.1   6.3      0.012   15.4   6.3    1.9  1  Prok-RING_4   Prokaryotic RING finger family 4
     0.0042   17.9   4.1     0.0085   17.0   4.1    1.5  1  DUF4482       Domain of unknown function (DUF4482)
     0.0045   17.1   6.1     0.0069   16.5   5.0    2.0  1  zf-C3HC4_4    zinc finger of C3HC4-type, RING
     0.0064   16.8   8.7      0.015   15.7   8.7    1.7  1  zf-RING_2     Ring finger domain
     0.0085   16.0   1.9      0.015   15.2   1.9    1.4  1  zf-RING_6     zf-RING of BARD1-type protein
  ------ inclusion threshold ------
      0.028   14.2   2.1      0.041   13.7   2.1    1.1  1  KASH_CCD      Coiled-coil region of CCDC155 or KASH
      0.028   14.3   5.8      0.028   14.3   5.8    1.8  2  zf-C3HC4_5    Zinc finger, C3HC4 type (RING finger)
       0.03   14.1   6.3       0.03   14.1   6.3    2.5  2  zf-C3HC4_2    Zinc finger, C3HC4 type (RING finger)
      0.031   14.2   1.1      0.051   13.6   1.1    1.3  1  FlxA          FlxA-like protein
        0.1   12.2   0.0       0.15   11.7   0.0    1.2  1  LdpA_C        Iron-Sulfur binding protein C terminal


Domain annotation for each model (and alignments):
>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   3.6     6e-09   7.7e-06       1      39 []     196     236 ..     196     236 .. 0.86

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 6e-09
  zf-RING_UBOX   1 CpIClelftdP.lvlpCGHtFCreClw.elskslegafkCP 39 
                   C  C  +f++  ++l+CGHt+C++C+   +sk++  ++ CP
    EEA18519.1 196 CALCHRTFNEEwKFLGCGHTLCQNCVDdIKSKHSLFEYPCP 236
                   99******9887779***********547788888888888 PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   8.7   2.4e-08     3e-05       3      48 ..     194     245 ..     192     247 .. 0.92

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 2.4e-08
                 SB-TTTSSS.BS-EEETTEEEEEE-HHHHHHHHH....TT-B-TT..T--B-- CS
  zf-C3HC4_3   3 eeCviCler.prnvvllpCgHlvlCeeCaekllk....rkkkCpi..Crrpie 48 
                  +C +C+++ ++++ +l CgH+ lC++C++++++     +  Cp+  C++pi 
  EEA18519.1 194 LKCALCHRTfNEEWKFLGCGHT-LCQNCVDDIKSkhslFEYPCPYttCQKPIL 245
                 68******97888*********.*********98999999****999***996 PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.9   4.5   8.9e-08   0.00011       1      39 [.     196     236 ..     196     242 .. 0.84

  Alignments for each domain:
  == domain 1  score: 21.9 bits;  conditional E-value: 8.9e-08
                 -TTT-S--SS-E.E-TTS--B-CHHHHHHHHC..TSSB--T CS
    zf-C3HC4   1 CpiCleeakepnelleCkHsfCskCirkilks..rkkvkCP 39 
                 C++C  ++ e+ ++l C+H++C++C++ i ++    +++CP
  EEA18519.1 196 CALCHRTFNEEWKFLGCGHTLCQNCVDDIKSKhsLFEYPCP 236
                 ***************************99886432234466 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   9.5   5.4e-06     0.007       1      34 [.     195     230 ..     195     242 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 5.4e-06
   zf-RING_5   1 hCnkCfeklskeekfyltsCgHifCekClkkll....e 34 
                 +C  C++ +  +e+  ++ CgH++C++C++  +     
  EEA18519.1 195 KCALCHRTF--NEEWKFLGCGHTLCQNCVDDIKskhsL 230
                 699******..999***************987755443 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   6.3   9.5e-06     0.012       1      38 [.     196     242 ..     196     247 .. 0.82

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 9.5e-06
  Prok-RING_4   1 CvlCgeq.ekkailepCgHlvCkeCfdskdls......sCPl..Cqr 38 
                  C lC +  +++  +  CgH +C++C d+ +++       CP   Cq+
   EEA18519.1 196 CALCHRTfNEEWKFLGCGHTLCQNCVDDIKSKhslfeyPCPYttCQK 242
                  9999998789999***************9766558888898433665 PP

>> DUF4482  Domain of unknown function (DUF4482)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   4.1   6.6e-06    0.0085      16      58 ..     151     193 ..     141     211 .. 0.85

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 6.6e-06
     DUF4482  16 kEkmeLldrfdrERkewesqwkelqkkieeLqkevklrrkinm 58 
                 kE +e  + +++E+++we+++ +lq +i+ Lq+++  r+  n+
  EEA18519.1 151 KEVLEPYEALEKEKRQWEKDKEILQAQIQFLQRQLGERKPRNI 193
                 788888899*************************999988665 PP

>> zf-C3HC4_4  zinc finger of C3HC4-type, RING
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   5.0   5.4e-06    0.0069      13      40 ..     209     236 ..     196     240 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 5.4e-06
  zf-C3HC4_4  13 sleCGhsfClsCisslqkepdgeqllCp 40 
                  l CGh+ C++C++ +  + +  +++Cp
  EEA18519.1 209 FLGCGHTLCQNCVDDIKSKHSLFEYPCP 236
                 589****************99999***9 PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   8.7   1.1e-05     0.015       2      42 ..     195     237 ..     194     241 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 1.1e-05
   zf-RING_2   2 eCpICleelssadsvlllpCgHvfhreClerwlrssst.....CPl 42 
                 +C++C   ++  +++  l CgH+ +++C++++  s+++     CP+
  EEA18519.1 195 KCALCHRTFN--EEWKFLGCGHTLCQNCVDDIK-SKHSlfeypCPY 237
                 7****98886..7888889************55.555559999*96 PP

>> zf-RING_6  zf-RING of BARD1-type protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   1.9   1.1e-05     0.015       6      38 ..     192     224 ..     188     244 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1.1e-05
   zf-RING_6   6 kllrcsrctdilrepvclggcehifcsncisdc 38 
                  +l+c+ c   + e   + gc h +c nc+ d 
  EEA18519.1 192 NILKCALCHRTFNEEWKFLGCGHTLCQNCVDDI 224
                 589***************************996 PP

>> KASH_CCD  Coiled-coil region of CCDC155 or KASH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   2.1   3.2e-05     0.041      71     111 ..     145     185 ..     143     196 .. 0.93

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 3.2e-05
    KASH_CCD  71 elkalvkeleEkrarlkaqnkqlekenqsLiakiesLqeen 111
                  lk+lvke+ E  + l+ +++q ek+++ L+a+i+ Lq ++
  EEA18519.1 145 KLKHLVKEVLEPYEALEKEKRQWEKDKEILQAQIQFLQRQL 185
                 589***********************************875 PP

>> zf-C3HC4_5  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.1       5.4   6.9e+03      40      47 ..     114     121 ..     113     123 .. 0.77
   2 ?   14.3   5.8   2.2e-05     0.028       4      51 .]     196     241 ..     194     241 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 5.4
  zf-C3HC4_5  40 dGPnqCPv 47 
                 d P +CP 
  EEA18519.1 114 DDPTRCPN 121
                 67999996 PP

  == domain 2  score: 14.3 bits;  conditional E-value: 2.2e-05
  zf-C3HC4_5   4 CPvCkssrYlnpdleflinpeCYhkmCesCvdRlFsdGP...nqCPvagCh 51 
                 C +C  +r +n++ +fl    C h++C++Cvd + s+      +CP+++C+
  EEA18519.1 196 CALC--HRTFNEEWKFL---GCGHTLCQNCVDDIKSKHSlfeYPCPYTTCQ 241
                 7777..5889*****99...7*************8876422279*****96 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   6.3   2.4e-05      0.03       1      30 [.     195     224 ..     195     236 .. 0.87
   2 ?    1.5   0.3      0.21   2.7e+02      17      31 ..     234     248 ..     222     251 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 2.4e-05
  zf-C3HC4_2   1 kCpiCldmlkdpsvvtpCgHvfCqkCilrs 30 
                 kC++C   +++      CgH+ Cq+C++  
  EEA18519.1 195 KCALCHRTFNEEWKFLGCGHTLCQNCVDDI 224
                 7**********99999**********9975 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.21
  zf-C3HC4_2  17 pCgHvfCqkCilrsL 31 
                 pC  ++Cqk il  L
  EEA18519.1 234 PCPYTTCQKPILSCL 248
                 9*******9887655 PP

>> FlxA  FlxA-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   1.1     4e-05     0.051      32      66 ..     149     186 ..     142     192 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 4e-05
        FlxA  32 qLkelses.deltkeekk..kqqqliqaQIqqlqaQIa 66 
                  +ke+ e  ++l ke ++  k ++ +qaQIq lq Q+ 
  EEA18519.1 149 LVKEVLEPyEALEKEKRQweKDKEILQAQIQFLQRQLG 186
                 44555555566666655576899999**********85 PP

>> LdpA_C  Iron-Sulfur binding protein C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00012      0.15     130     178 ..     131     179 ..      93     185 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00012
      LdpA_C 130 keesasiaGvAyGsyARkllspileklekkekskaeleeepellkeave 178
                 k++++ ++Gv + s  ++l++++le  e+ ek+k ++e+ +e+l++ ++
  EEA18519.1 131 KRKREDVDGVDFRSKLKHLVKEVLEPYEALEKEKRQWEKDKEILQAQIQ 179
                 348899**************************************98876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (257 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1266  (0.0706119); expected 358.6 (0.02)
Passed bias filter:                      866  (0.0483016); expected 358.6 (0.02)
Passed Vit filter:                       118  (0.00658152); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.57u 0.31s 00:00:00.87 Elapsed: 00:00:00.48
# Mc/sec: 1613.67
//
Query:       EEA18520.1  [L=175]
Description: hypothetical protein PMAA_007990 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (175 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       346  (0.0192983); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.28s 00:00:00.71 Elapsed: 00:00:00.46
# Mc/sec: 1154.49
//
Query:       EEA18521.1  [L=65]
Description: hypothetical protein PMAA_008000 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (65 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       803  (0.0447878); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.45
# Mc/sec: 434.36
//
Query:       EEA18522.1  [L=526]
Description: cell surface metalloreductase (FreA), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.2e-09   37.3   0.0    6.9e-09   35.8   0.0    1.8  2  FAD_binding_8  FAD-binding domain
    1.8e-07   31.4   0.1    3.5e-07   30.5   0.1    1.5  1  NAD_binding_6  Ferric reductase NAD binding domain
    6.4e-06   26.3   9.7    6.4e-06   26.3   9.7    3.3  4  Ferric_reduct  Ferric reductase like transmembrane component
  ------ inclusion threshold ------
      0.061   12.9   0.1       0.13   11.8   0.1    1.5  1  TEP1_N         TEP1 N-terminal domain


Domain annotation for each model (and alignments):
>> FAD_binding_8  FAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.8   0.0   1.5e-12   6.9e-09      18     108 ..     271     356 ..     258     357 .. 0.86
   2 ?   -3.0   0.0       1.7   7.6e+03      63      85 ..     406     428 ..     403     444 .. 0.75

  Alignments for each domain:
  == domain 1  score: 35.8 bits;  conditional E-value: 1.5e-12
  FAD_binding_8  18 klkvskpkkslkykaGqyvyinipslsklfw.qsHPFtiasape..ddklslvikvksgltkklakkllssskkelenkkaklkvlidGPYGap 108
                    ++ +++p +    +aGqy+ + +ps+  ++w q+HPF ++s ++  ++ l+++i+ + g++++l k+   +    + ++ a+l+ li GP G +
     EEA18522.1 271 RVALTRPAR---IEAGQYINLWMPSVTWWSWaQVHPFMVTSWSHsaQEALDILIQPRHGFSRELLKHARAA----P-QGSASLRALIIGPHGMS 356
                    455666665...9**************885559********999889********************9998....5.88899999999999976 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.7
  FAD_binding_8  63 klslvikvksgltkklakkllss 85 
                     l++ i+v+++l + l+  +l++
     EEA18522.1 406 TLDIAIAVQATLNSLLEDDILKK 428
                    67788888888888887777765 PP

>> NAD_binding_6  Ferric reductase NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.5   0.1   7.7e-11   3.5e-07       1      74 [.     362     438 ..     362     457 .. 0.87

  Alignments for each domain:
  == domain 1  score: 30.5 bits;  conditional E-value: 7.7e-11
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxx RF
  NAD_binding_6   1 yenvllvagGiGitpfisilkdllkkskkealktkkikliwvvressslewfkdvLneleeekse...gnieihiYl 74 
                    ye+v+lva+G Gi+ +i+ lk+l++ ++++a +t++++l+w v   +   +++  Ln+l e +       + i+iY+
     EEA18522.1 362 YESVVLVASGFGIAAAIPYLKKLVYSYNTSASRTRRVHLVWEVETLDIAIAVQATLNSLLEDDILkkrYILTISIYV 438
                    89********************************************9999999999988876544333556666665 PP

>> Ferric_reduct  Ferric reductase like transmembrane component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   1.5     0.025   1.1e+02       6      55 ..      16      69 ..      11      75 .. 0.73
   2 !   26.3   9.7   1.4e-09   6.4e-06       2     124 ..      91     200 ..      90     201 .. 0.86
   3 ?   -0.7   0.2      0.32   1.5e+03       5      32 ..     219     250 ..     216     255 .. 0.70
   4 ?   -4.0   0.0       3.4   1.5e+04      43      60 ..     294     311 ..     291     330 .. 0.68

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.025
  Ferric_reduct  6 lillplall.....lalRnnfle.pltglsldklll.fHkwlgvlafllallHvily 55
                   ++l+ +++l     la   ++le  ++++ +  + l  H+ +g ++   +l+H ++ 
     EEA18522.1 16 VALFLISILpylyqLA---KSLEvYISRYLIFPFFLrRHRFVGPWTRGAVLIHLLYT 69
                   5555555554444455...677788999999985555****************9875 PP

  == domain 2  score: 26.3 bits;  conditional E-value: 1.4e-09
  Ferric_reduct   2 GiaalillplalllalRnnflepltglsldklllfHkwlgvlafllallHvilyllnflrfsaldeerlldsllkkpynllGvlalllliilaitS 97 
                    G++a++++ +++  +   +f++ ++ +s  + l +H+ +++++  l++lHv+l+   +        ++l+ +++++ + l+G + +   + la+++
     EEA18522.1  91 GTLAVVNMVASYTAG-HVSFYSDILSISRHTCLQIHRGTAWMVSGLLVLHVVLISTIQ--------RGLSLDRTSNVFALTGGGCV---VGLAVFA 174
                    999*********977.889999*****************************9998765........45677788888877777665...5567899 PP

  Ferric_reduct  98 lkfirrrlsyelFyylHhllyvaylll 124
                    l++i  r+ +e+F+ +H++l+ ++l++
     EEA18522.1 175 LPYIH-RHIFEVFLRTHQVLAYILLYV 200
                    99***.9999*********99998865 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 0.32
  Ferric_reduct   5 alillplall.....lalRnnflepltglsldk 32 
                     ++ll++all     l  Rn++++ l+g++  +
     EEA18522.1 219 TFVLLSIALLlqlgfLIYRNKVFS-LHGWPRAR 250
                    577788888866554447998885.88888776 PP

  == domain 4  score: -4.0 bits;  conditional E-value: 3.4
  Ferric_reduct  43 lafllallHvilyllnfl 60 
                    + + +a +H ++ + +  
     EEA18522.1 294 TWWSWAQVHPFMVTSWSH 311
                    556677777777766544 PP

>> TEP1_N  TEP1 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.1     3e-05      0.13       5      17 ..     104     116 ..     103     118 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3e-05
      TEP1_N   5 hGhvSaHpDILSL 17 
                  GhvS ++DILS 
  EEA18522.1 104 AGHVSFYSDILSI 116
                 6***********5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (526 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       704  (0.039266); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 3447.04
//
Query:       EEA18523.1  [L=187]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0013   18.9   0.0     0.0025   18.0   0.0    1.5  1  FtsJ      FtsJ-like methyltransferase


Domain annotation for each model (and alignments):
>> FtsJ  FtsJ-like methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   1.4e-07    0.0025      86     133 ..      30      79 ..       8     117 .. 0.78

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 1.4e-07
                 SSEEEEEE--S-SS-CHHHHHHHHH....CCCCHHHHCCHCCCCECCCEEEE CS
        FtsJ  86 rkvdlvvsDgapdvsgvhdldeylq....sqLllaalelalkllkpggtfvl 133
                 + +dl+++Dg   v  +hd   y++    s+L la+l+l l+ l+pggt+++
  EEA18523.1  30 QSFDLIICDGQ--VLRNHDRAGYRErteaSRLSLAQLTLPLDHLNPGGTMIV 79 
                 679*******8..77778888888888889*******************984 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (187 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       387  (0.0215851); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.30s 00:00:00.73 Elapsed: 00:00:00.46
# Mc/sec: 1223.21
//
Query:       EEA18524.1  [L=481]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
     0.0006   19.8   1.5     0.0006   19.8   1.5    2.8  2  zf-CCHC       Zinc knuckle
     0.0049   16.9   3.6     0.0049   16.9   3.6    2.4  3  ArfGap        Putative GTPase activating protein for Arf
     0.0057   16.0  10.9     0.0057   16.0  10.9    3.0  3  FAM76         FAM76 protein
  ------ inclusion threshold ------
       0.46   11.1  11.9      0.093   13.4   7.2    2.3  2  SlyX          SlyX
        1.1    9.1   7.5       0.79    9.6   1.7    2.5  2  PKcGMP_CC     Coiled-coil N-terminus of cGMP-dependent protei
        1.5    8.2   6.4        1.8    7.9   3.4    2.0  2  YjcZ          YjcZ-like protein
        2.6    7.5   9.7        1.4    8.4   6.0    1.9  2  Exonuc_VII_L  Exonuclease VII, large subunit
        5.4    6.7   9.6       0.35   10.6   3.1    2.3  3  DUF4972       Domain of unknown function (DUF4972)


Domain annotation for each model (and alignments):
>> zf-CCHC  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   1.5   2.7e-07    0.0006       2      18 .]     355     371 ..     354     371 .. 0.94
   2 ?    1.2   5.1       0.2   4.5e+02       2      12 ..     374     384 ..     373     389 .. 0.83

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 2.7e-07
                 CTSSSSSSSSTTTTSTS CS
     zf-CCHC   2 kCynCGepGHiardCpk 18 
                 +C+nC+e+GH a  C+k
  EEA18524.1 355 QCFNCQEIGHKAFACKK 371
                 6**************96 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.2
                 CTSSSSSSSST CS
     zf-CCHC   2 kCynCGepGHi 12 
                 +C +C + GH 
  EEA18524.1 374 TCAKCAGKGHH 384
                 8*********7 PP

>> ArfGap  Putative GTPase activating protein for Arf
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.1       1.8   4.1e+03      63      91 ..     105     131 ..      72     148 .. 0.58
   2 ?   -2.6   0.1       2.5   5.6e+03      11      21 ..     351     361 ..     342     369 .. 0.71
   3 !   16.9   3.6   2.2e-06    0.0049      11      83 ..     370     442 ..     360     454 .. 0.92

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 1.8
                 HHHHHHHHHTCHHHHHHHHTTTC-TTTSG CS
      ArfGap  63 deelellkalgNkkaneileaklpkeekr 91 
                 +e+ e++++ g +   + l+a+l++ +++
  EEA18524.1 105 KEQSEMIREQGAS--IKELQAQLEATQSQ 131
                 4555555555543..22333333333333 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 2.5
                 CCCCB-TTT-S CS
      ArfGap  11 penkvCaDCga 21 
                  + + C++C++
  EEA18524.1 351 TGPAQCFNCQE 361
                 45568999975 PP

  == domain 3  score: 16.9 bits;  conditional E-value: 2.2e-06
                 CCCCB-TTT-SBS--EEETTTTEEE-HHHHHHHCCS.TTT--EEETTTS---HHHHHHHHHTCHHHHHHHHTT CS
      ArfGap  11 penkvCaDCgakeptWaslnlgvflCieCsgvHrslgvhiskvrsltldkwedeelellkalgNkkaneilea 83 
                 +++++Ca C  k  ++ +++  v+ C+ C g H s++++     + + d++ +++ +  +   Nk+a+++++ 
  EEA18524.1 370 KKSQTCAKCAGKGHHHSTCQAVVLKCVPCGGPHESFSKNCRGWNNPEGDRFFEKQRQAADYADNKTAKQFYKM 442
                 6789******************************************************************986 PP

>> FAM76  FAM76 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0  10.9   2.6e-06    0.0057     168     275 ..      31     144 ..       8     148 .. 0.71
   2 ?    0.7   0.1      0.12   2.7e+02     145     234 ..     198     246 ..     172     296 .. 0.52
   3 ?   -4.7   9.8       5.5   1.2e+04      66     106 ..     353     395 ..     348     397 .. 0.85

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 2.6e-06
       FAM76 168 ekkaskkkskkh.kkrssrlevskleeek.....laeekesnetskksldsnssdhlvavtqLkeeiaslkkqleqkdqellekdkkitelkaelleke 260
                 +++++++ + k+ kk+ ++++ +++++       ++++k +++++ +++ +     l++v+ Lke++ + +++++++ +++ e+   i el+a+l+ ++
  EEA18524.1  31 SSSTDNTDTVKTsKKSMTQVDLTAVKKAAslideKQRTKDGSKDMLRMICQYLEKTLLEVKGLKETLSKQERMIKEQSEMIREQGASIKELQAQLEATQ 129
                 22222222222213333344444444222332224566677777777888899999******************************************* PP

       FAM76 261 kelreklkelekeak 275
                 +++ e  ++l+k+++
  EEA18524.1 130 SQNTEECEQLQKQIE 144
                 ********9999876 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.12
       FAM76 145 krskskkkkskskkskkskekskekkaskkkskkhkkrssrlevskleeeklaeekesnetskk......sldsnssdhlvavtqLkeeiaslkkq 234
                  r++ +k+ + s+++k                                               +        d ++ d++ ++ + +eei++ k  
  EEA18524.1 198 IRQRIEKEMRGSEQTK-----------------------------------------------NwrcaamIKDHKNADRVKVICRNEEEIQQVKEA 246
                 2222222222222222...............................................112222233333333443444444444433333 PP

  == domain 3  score: -4.7 bits;  conditional E-value: 5.5
       FAM76  66 PkaCelCnii..aaFigskCqRCtnsekkyGkpvtCeqCkqkc 106
                 P +C  C+ i   aF  +k q C+++  k  +  tC+    kc
  EEA18524.1 353 PAQCFNCQEIghKAFACKKSQTCAKCAGKGHHHSTCQAVVLKC 395
                 8899999865337**************9999999999888887 PP

>> SlyX  SlyX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   7.2   4.2e-05     0.093       8      49 ..      93     134 ..      89     167 .. 0.86
   2 ?   -3.5   0.1       7.7   1.7e+04      25      39 ..     232     246 ..     231     250 .. 0.53

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 4.2e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT-XX CS
        SlyX   8 LEiklafqedtieeLndvvaeqqqqidrlqrqlrllaerlke 49 
                 L + l+ qe++i+e ++++ eq   i++lq+ql++ + +  e
  EEA18524.1  93 LKETLSKQERMIKEQSEMIREQGASIKELQAQLEATQSQNTE 134
                 678899****************************99887643 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 7.7
                 HHHHHHHHHHHHHHH CS
        SlyX  25 vvaeqqqqidrlqrq 39 
                 v+ + +++i++ ++ 
  EEA18524.1 232 VICRNEEEIQQVKEA 246
                 455555566555544 PP

>> PKcGMP_CC  Coiled-coil N-terminus of cGMP-dependent protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   1.7   0.00035      0.79       5      32 ..      98     126 ..      95     129 .. 0.90
   2 ?    2.0   0.4     0.084   1.9e+02      16      28 ..     232     244 ..     220     247 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00035
   PKcGMP_CC   5 lKDER.IRELEkrlaekdeEIqELrskLD 32 
                 +K ER I+E  ++++e+ + I+EL ++L 
  EEA18524.1  98 SKQERmIKEQSEMIREQGASIKELQAQLE 126
                 677887*********************95 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.084
   PKcGMP_CC  16 rlaekdeEIqELr 28 
                  +++ +eEIq+ +
  EEA18524.1 232 VICRNEEEIQQVK 244
                 68999*****987 PP

>> YjcZ  YjcZ-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   3.4   0.00081       1.8      38     122 ..      63     146 ..      29     158 .. 0.80
   2 ?    0.7   0.0      0.13   2.8e+02      20      52 ..     193     225 ..     176     240 .. 0.77

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.00081
        YjcZ  38 qlraseinaevnaalelrLkllekLsreldpghLALttiaqrlallsqtlaekasaapklaqalaalaeefaarverkekaltqr 122
                   ++ + ++  ++ l +  ++lek   e++  +  L++  + +   s++  e++  +++l+ +l+a++ + ++ +e++ k++   
  EEA18524.1  63 DEKQRTKDGS-KDMLRMICQYLEKTLLEVKGLKETLSKQERMIKEQSEMIREQGASIKELQAQLEATQSQNTEECEQLQKQIETI 146
                 4444444444.567999999999999999999999*********************************************99865 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.13
        YjcZ  20 arqqkfreRLlqellastqlraseinaevnaal 52 
                  +   +r+R+ +e+ +s q +++  +a+++++ 
  EEA18524.1 193 VQIADIRQRIEKEMRGSEQTKNWRCAAMIKDHK 225
                 345689**********************99975 PP

>> Exonuc_VII_L  Exonuclease VII, large subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   6.0   0.00062       1.4     163     262 ..      39     149 ..       9     164 .. 0.54
   2 ?    0.3   0.1      0.18   4.1e+02     146     201 ..     192     249 ..     169     301 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00062
  Exonuc_VII_L 163 lleekkqrleklasrlkspeellerkrqrldeleerleralkkqlkkkrerleelkerl.k.........ekleekkerlkklkerle.lleekker 248
                   +++++k+ +++++ +  ++ + l +++qr ++ ++++ r++ + l+k   +++ lke+l k         e ++e+ +++k+l+++le + ++++e+
    EEA18524.1  39 TVKTSKKSMTQVDLTAVKKAASLIDEKQRTKDGSKDMLRMICQYLEKTLLEVKGLKETLsKqermikeqsEMIREQGASIKELQAQLEaTQSQNTEE 135
                   3344444444444333333333334444444444444444555544444444444444432332222333444455555577777776556777777 PP

  Exonuc_VII_L 249 leeleeklealspl 262
                   +e+l++++e++s+ 
    EEA18524.1 136 CEQLQKQIETISYA 149
                   88888888777765 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.18
  Exonuc_VII_L 146 eeqleelerrlekaikrlleekkqrleklasrlkspee..llerkrqrldeleerler 201
                   + q++++++r+ek+++   ++k+ r  ++ ++ k++++  ++ r+++++++++e  ++
    EEA18524.1 192 KVQIADIRQRIEKEMRGSEQTKNWRCAAMIKDHKNADRvkVICRNEEEIQQVKEAAQK 249
                   5566677777777776666666666665544443332222555555555555544443 PP

>> DUF4972  Domain of unknown function (DUF4972)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   3.1   0.00015      0.35      47     123 ..      43     117 ..      25     127 .. 0.77
   2 ?   -2.3   0.0       1.4   3.2e+03      82     103 ..     134     155 ..     126     160 .. 0.74
   3 ?   -2.7   0.2         2   4.5e+03      85     115 ..     234     248 ..     218     251 .. 0.52

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00015
     DUF4972  47 eqleelinkltdLrdesqyGekkgmYPeesraiLedaivklkesiakikegnkaeaeeeadrlikeakkaieeFkat 123
                 ++ +  +  lt++++ +   + k +    s+++L    ++l++++ ++k  +++ +++  +r+ike  ++i e  a 
  EEA18524.1  43 SKKSMTQVDLTAVKKAASLIDEKQRTKDGSKDMLRMICQYLEKTLLEVKGLKETLSKQ--ERMIKEQSEMIREQGAS 117
                 44455677899999999999999999**********************9988888754..57788777777665554 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1.4
     DUF4972  82 daivklkesiakikegnkaeae 103
                 ++  +l++ i++i +++++ ++
  EEA18524.1 134 EECEQLQKQIETISYAGVVGSQ 155
                 5667888999999988887775 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 2
     DUF4972  85 vklkesiakikegnkaeaeeeadrlikeakk 115
                  + +e i+++ke+                 +
  EEA18524.1 234 CRNEEEIQQVKEA----------------AQ 248
                 3334444444443................33 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (481 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2328  (0.129846); expected 358.6 (0.02)
Passed bias filter:                      723  (0.0403257); expected 358.6 (0.02)
Passed Vit filter:                        98  (0.005466); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.69u 0.32s 00:00:01.01 Elapsed: 00:00:00.47
# Mc/sec: 3055.58
//
Query:       EEA18525.1  [L=685]
Description: urea active transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.7e-18   65.6  30.9      8e-18   64.5  30.7    1.7  1  SSF       Sodium:solute symporter family


Domain annotation for each model (and alignments):
>> SSF  Sodium:solute symporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.5  30.7   4.5e-22     8e-18       1     406 []      60     476 ..      60     476 .. 0.76

  Alignments for each domain:
  == domain 1  score: 64.5 bits;  conditional E-value: 4.5e-22
         SSF   1 yflagrsltgfvlglslaasnisaasfvGlaGavaasGlav.vllelgalllvlllllllaerlr.nagalTlpdylskRfkgkrilvylsalslllvi 97 
                 +++a+r +    ++ ++ +s + +  ++G + +++ +G+a+ ++++ g  +++++  ll +   r    a T  ++++ R++     v++ +l  l+  
  EEA18525.1  60 FMTANRTVRTGLTASAVVSSWLWSTALLGSSLVGYNYGVAGpFWFAAGCSPMIVFFALLGVSCKRkIPEAHTSLEVVRVRYGRVA-HVVFMIL-CLINN 156
                 78999*999999***************************97478899998887776666555555245789999********988.5555555.56677 PP

         SSF  98 tlklsvdlvggaklielalGlnyetavlllaaltalYtviGGllAvvytdtiqavlmlvgalilli..ivllevGgleslveklkeaapkv..vdlltp 192
                 +++++  l+g+ + i  + G+ + +  +ll + + lYt++GG+ A+ +td   +v++++ a+  +i  ++++e+G+  +l + +++a  +   + + + 
  EEA18525.1 157 IFACANMLLGASAVISAMTGMHVIAVTFLLPLGVSLYTFVGGIKATFLTDYFHTVVIVLVACYFSIkaFTFSEIGSAGNLYDLVQAAGARNpvSGNAQ- 254
                 789********************9999***************************998887776555228899***99999998888877554233333. PP

         SSF 193 dslkllrdpltalslwlglvlGvagl....philvRflaak.....dakailkgvlkltivlilvligmisiilfaiklagavpkavgtevgvsniayp 282
                  ++ l     +a+++++  + G +gl        ++ +aa+      + +i      ++++ +  ++  ++++l    ++   p+ ++t+   s +++p
  EEA18525.1 255 -GTYLTMTSKDAILFGIIHICGNFGLvimdTSYFIKAFAASpaavvPGYTIGGIAYFAIPWALGTVMSCVAVGLENTPVFPTYPRRMTTSEVSSGLVLP 352
                 .32234444445555555555555555547555667777763444334444433344566666666667****************************** PP

         SSF 283 eLvvkllpnllaGlllavmlAaimstltslllsassaftkDlYkkirrkasakekelvgvsr..iivlvvislaillavqeeqkgvlklvelafaglas 379
                   +  + +++ a+ ++ + + a+ stl++++++ ss+++ D+Y + + k  a+++++++ s   +++    s a+  ++       l+   ++ ++++ 
  EEA18525.1 353 FSALTIAGSGGAAAVILITFMAVTSTLSAQVIAVSSIISFDIYREYFNKS-ASDRQIIRWSHfgVVFFAFFSAAFSTMLYYVGA-DLQWTLYMLGVVTC 449
                 *************9999****************************99998.777777776651244445555555444444444.34556677777888 PP

         SSF 380 avlavillalfwkrvneqGAlagliiG 406
                 + +  + +++ w   n+  A+ + i+G
  EEA18525.1 450 PGIFPMAFTVLWRGQNTLAAILAPILG 476
                 878888888888888888888777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (685 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       960  (0.0535445); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.67u 0.32s 00:00:00.99 Elapsed: 00:00:00.50
# Mc/sec: 4095.24
//
Query:       EEA18526.1  [L=484]
Description: xenobiotic compound monooxygenase, DszA family, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.3e-54  185.8   0.6    1.6e-54  185.4   0.6    1.1  1  Bac_luciferase  Luciferase-like monooxygenase


Domain annotation for each model (and alignments):
>> Bac_luciferase  Luciferase-like monooxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  185.4   0.6   9.1e-59   1.6e-54      19     313 ..      37     405 ..      22     406 .. 0.90

  Alignments for each domain:
  == domain 1  score: 185.4 bits;  conditional E-value: 9.1e-59
  Bac_luciferase  19 s...aslrylvelaraaEelGfdavwvaehhggpgga..................ldaftllaalaaaTerirlgtavtplytrhPavlAqqaat 92 
                     s    ++++ +ela+++Ee++f+++++a+ +gg +                     +++++  a+aaaT++i++g++v ++y  +P++lA+   t
      EEA18526.1  37 SwrfNDVHHWIELAKLLEEAKFHGIFIADVLGGYDVYkgprnldpaiisgaqwpvNEPLSVVPAMAAATKNIGFGVTVATTY-EQPYHLARRLST 130
                     2455789999**********************98888*********************************************.************ PP

  Bac_luciferase  93 LdhlsgGRf..glglgtggpaveerrfGv....dhderyarlrEfvevlrrlwrg.....................eev.dfeGeffsvkgalll 159
                     +dhl++GRf  g++++tg   + +r+ G+     hd+rya ++E+v++  +lw++                      +  ++eG++++v g+++ 
      EEA18526.1 131 VDHLTNGRFriGWNIVTGYLDSAARNLGRfeqpQHDDRYAIAEEYVKITYKLWESswrddavvrdrergvytepsrVRLiNHEGKYYTVPGPHIC 225
                     ********97789****************************************6699999****************6666*************99 PP

  Bac_luciferase 160 prpgqgpiP.vyvaaaspaglelaarhadglllageppeeaaelierlra.gaaeagrdpadirvgisltvivadteeeAraearaliagld... 249
                      +++q+  P ++ a++s ag  +aa ha+++++ag +p  + + i+++r+ +  e+grdp ++++++ + +++++teeeA+++++++   +    
      EEA18526.1 226 QPSPQR-TPlILQAGTSKAGKSFAAHHAEAIFVAGHSPSVVSKNIAEIRElARTEFGRDPRSLKFLALFCPVLGRTEEEAQKKFDDYRNIGSieg 319
                     999888.9*88888899*********************************55568*****************************88886666899 PP

  Bac_luciferase 250 ..............fyaldsegagreaeaaeiqeeedanlwagaadavpdelvaatal.......vGtpeqvaerlaa.yaeagvd 313
                                   +y +d+e+ + e +a ++  e ++++  g+ +  +  + + +++       vGtp+qva++l++ +aea vd
      EEA18526.1 320 alalfggwtgidlnQYDDDQELRHVESNAIRSAVEAWSKASPGVVKWTKVTVAQHITVgglgttsVGTPKQVADELERwVAEADVD 405
                     9999999*******9999999999999999888888888888888886555555555588889***************66776665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (484 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       361  (0.020135); expected 358.6 (0.02)
Passed bias filter:                      338  (0.0188521); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.30s 00:00:00.83 Elapsed: 00:00:00.46
# Mc/sec: 3162.83
//
Query:       EEA18527.1  [L=70]
Description: hypothetical protein PMAA_008060 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0045   17.0   0.0     0.0063   16.6   0.0    1.3  1  LysM      LysM domain


Domain annotation for each model (and alignments):
>> LysM  LysM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   3.5e-07    0.0063       1      43 [.      22      66 ..      22      67 .. 0.86

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 3.5e-07
                EEE-TT--HHHHHHHCTCHHHHHHHHC.TCSSCG.G--TTEEEEE CS
        LysM  1 YtVkkGDTLwsIAkrygitveklleaN.nlsspd.kifpGqkLki 43
                +tV  GDT   I +  git+ +l e+N  ++s+  ++ +G + ++
  EEA18527.1 22 HTVVIGDTFAVIENEDGITFTQLDEWNaAIRSNCeTLDVGYVVCV 66
                8**************************955554456988887776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (70 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       347  (0.0193541); expected 358.6 (0.02)
Passed bias filter:                      298  (0.0166211); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.31s 00:00:00.73 Elapsed: 00:00:00.48
# Mc/sec: 440.86
//
Query:       EEA18528.1  [L=558]
Description: retrovirus polyprotein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.6e-33  114.7   0.0    3.5e-33  113.6   0.0    1.5  1  RT_RNaseH_2   RNase H-like domain found in reverse transcript
    3.9e-33  113.9   0.0    7.5e-33  113.0   0.0    1.5  1  RT_RNaseH     RNase H-like domain found in reverse transcript
    5.5e-30  104.5   0.2    9.6e-30  103.8   0.2    1.4  1  RVT_1         Reverse transcriptase (RNA-dependent DNA polyme
  ------ inclusion threshold ------
       0.19   11.6   0.0        1.2    8.9   0.0    2.0  2  Herpes_IE2_3  Herpes virus intermediate/early protein 2/3


Domain annotation for each model (and alignments):
>> RT_RNaseH_2  RNase H-like domain found in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.6   0.0   7.8e-37   3.5e-33       1      95 [.     380     474 ..     380     482 .. 0.98

  Alignments for each domain:
  == domain 1  score: 113.6 bits;  conditional E-value: 7.8e-37
  RT_RNaseH_2   1 WteeqekafeklkealtsapvLahpdpdkpfiletDaSdtgigavLsqedddgkerpiafaSrklskaernysttekellAivwalkkfrhyllg 95 
                  Wte++++af++lke+l sapvL+h+dp++++ +etDaSd  +++vLsq  +dg+++p++++S ++ +ae+ny++++kellAi++a++++++ llg
   EEA18528.1 380 WTEDCQRAFDTLKERLGSAPVLTHYDPKRQTRVETDASDGVVAGVLSQFCKDGEWHPVGYYSATMAPAEHNYHIHDKELLAIIKAFHEWKPELLG 474
                  *******************************************************************************************9998 PP

>> RT_RNaseH  RNase H-like domain found in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.0   0.0   1.7e-36   7.5e-33       1     105 []     405     513 ..     405     513 .. 0.96

  Alignments for each domain:
  == domain 1  score: 113.0 bits;  conditional E-value: 1.7e-36
                 -TTS-EEEEEEECTEEEEEEEEEETTE..EEEEEEEEEE--HHHHTS-HHHHHHHHHHHHHHHHHHHHTS.--...EEEE-SS--TTTTT----.---H CS
   RT_RNaseH   1 dpskpfiletDAsddgigavLsqreedgeerpiafaSrklsgaernystiekellAivaalkkfrhylqg.rk...ftvitDhknlkyllskkslngrl 95 
                 dp++++ +etDAsd ++++vLsq  +dge++p+ ++S ++ +ae+ny++++kellAi++a++++++ l g r+   f+v++Dh++l+y++++k l++r+
  EEA18528.1 405 DPKRQTRVETDASDGVVAGVLSQFCKDGEWHPVGYYSATMAPAEHNYHIHDKELLAIIKAFHEWKPELLGlRSeerFEVLSDHRALEYFMTTKALSARQ 503
                 899****************************************************************998842358*********************** PP

                 HHHHHHC-XX CS
   RT_RNaseH  96 arWaleLsey 105
                  rW ++L+e+
  EEA18528.1 504 VRWYEFLQEF 513
                 ********98 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.8   0.2   2.1e-33   9.6e-30       1     222 []     157     317 ..     157     317 .. 0.97

  Alignments for each domain:
  == domain 1  score: 103.8 bits;  conditional E-value: 2.1e-33
                 EE-TT.S-EEE.......-THHHHCTB--.........-------HHHH.............HCCHTS--EEEEEEBCCGCCCSBB-GGGGGGG-EEET CS
       RVT_1   1 ipKkgpgsyRp.isllsvdykalnkliakrLkdvlekllsenqpgfrpgrstldavedllkalkkkkkaklllklDlkkaFdsvpleellrkltafkvp 98 
                 ++K + g+ R  +     dy++ln+l+ k         + +++p +++               ++ +kak+++klD++++F++++++++++ lt+f+++
  EEA18528.1 157 VKKAD-GGLRFcV-----DYRKLNALTRK---------DRYPLPLIDEV-------------FERIHKAKIFTKLDIRQGFHRIRMSADSSDLTTFRCR 227
                 68999.*****55.....***********.........***********.............7899********************************* PP

                 .........................TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T......TEEECTTEEEEEESSHHHHHHHHHHHHHHHHHTT-- CS
       RVT_1  99 tklinliksflstrsfsvrvngeeskgryekkglpqGsvlSPllfnlfmnellrelrkrakgvtllrYaDDililskskeelqelleaveewlkesglk 197
                                          +g + ++++p+G++++P++f++++n+++ ++       +l++++DD+li+s+++ e++++++ v e+l+ +gl+
  EEA18528.1 228 -------------------------YGTFKYEVMPFGLTNGPATFQRLINDIFLDCLD----KFLIAFVDDLLIYSNDELEHETHVKFVLERLRAAGLQ 297
                 .........................9*******************************9....59*********************************** PP

                 BEGGG-EEE.....ESSEEETTEEE CS
       RVT_1 198 inpeKtklvlftvkseevkyLGvtl 222
                  + +K+++       ++ kyLG+++
  EEA18528.1 298 ASIKKCEFH-----VTTTKYLGFII 317
                 *********.....8*******986 PP

>> Herpes_IE2_3  Herpes virus intermediate/early protein 2/3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.1      0.18     8e+02      49      79 ..       3      33 ..       1      45 [. 0.81
   2 ?    8.9   0.0   0.00028       1.2      26      88 ..     371     433 ..     350     436 .. 0.82

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.18
  Herpes_IE2_3 49 kLlslpNltvsapfqleitepvthepdviar 79
                  ++    N++vs+p + e  +   h+ ++++ 
    EEA18528.1  3 RMQRQLNVAVSEPTEKEELKRSSHKAKTVHS 33
                  677788*******999999999999888865 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.00028
  Herpes_IE2_3  26 akqiqifytRskevknaidalrekLlslpNltvsapfqleitepvthepdviarikelckdgv 88 
                     +i + +   +++++a+d+l+e+L+s p lt   p++    e+   + +v+  ++++ckdg 
    EEA18528.1 371 LTKIDVPFKWTEDCQRAFDTLKERLGSAPVLTHYDPKRQTRVETDASDGVVAGVLSQFCKDGE 433
                   456788889999************************9999999999999***********985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (558 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       450  (0.025099); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 3686.68
//
Query:       EEA18529.1  [L=130]
Description: hypothetical protein PMAA_008080 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    0.00014   21.8   0.7    0.00023   21.1   0.7    1.4  1  zf-CCHC          Zinc knuckle
  ------ inclusion threshold ------
      0.034   13.9   0.1      0.076   12.8   0.1    1.6  1  zf-CCHC_4        Zinc knuckle
       0.13   13.2   3.6       0.73   10.8   2.7    2.3  2  Cytochrome_C554  Cytochrome c554 and c-prime


Domain annotation for each model (and alignments):
>> zf-CCHC  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.1   0.7   3.8e-08   0.00023       1      17 [.      82      98 ..      82      99 .. 0.95

  Alignments for each domain:
  == domain 1  score: 21.1 bits;  conditional E-value: 3.8e-08
                SCTSSSSSSSSTTTTST CS
     zf-CCHC  1 rkCynCGepGHiardCp 17
                +kC+nC  pGH+a  Cp
  EEA18529.1 82 KKCFNCKLPGHRADKCP 98
                59**************9 PP

>> zf-CCHC_4  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.1   1.3e-05     0.076      32      48 ..      82      98 ..      80      99 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.3e-05
   zf-CCHC_4 32 sfCyiCgvlGHsdkrCd 48
                ++C++C + GH +++C+
  EEA18529.1 82 KKCFNCKLPGHRADKCP 98
                57**************8 PP

>> Cytochrome_C554  Cytochrome c554 and c-prime
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.1     0.096   5.7e+02      53      63 ..      22      32 ..       2      52 .. 0.67
   2 ?   10.8   2.7   0.00012      0.73      20      73 ..      54     105 ..      20     112 .. 0.74

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.096
                     GGSBSTTTSTT CS
  Cytochrome_C554 53 kCHatgagkdk 63
                     +CH+t+ + ++
       EEA18529.1 22 SCHTTANRLEQ 32
                     57777665555 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00012
                      GTTGGGSTTSSHHHHHHTT--TTS--TT-TTTGGGSBSTTTSTT---SSS--GG CS
  Cytochrome_C554  20 kaleslkkekkaeakkkakldpakdaeeapeClkCHatgagkdkgfvlkektkl 73 
                      k + + k+++++  +++ + +++k+   +++C++C  +g+++dk   l++kt+ 
       EEA18529.1  54 KGITESKPKDETP-RSNLSFTKRKQLIAEKKCFNCKLPGHRADKCP-LQKKTPD 105
                      4555566655544.445556667888899**************965.5555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (130 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       946  (0.0527637); expected 358.6 (0.02)
Passed bias filter:                      389  (0.0216967); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.38u 0.26s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 976.22
//
Query:       EEA18530.1  [L=264]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
      0.011   16.0   0.1      0.032   14.5   0.1    1.8  1  Retrotrans_gag  Retrotransposon gag protein


Domain annotation for each model (and alignments):
>> Retrotrans_gag  Retrotransposon gag protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.1   1.8e-06     0.032       8      78 ..     189     259 ..     181     264 .] 0.74

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 1.8e-06
  Retrotrans_gag   8 egaAkswlkslvarsidasesWkdlkkaflktflpserkdqleeelsslrQgtesvreYvtrfktladqld 78 
                      +aA + l +++ +s+++    +d+ +++++ + +++r   ++ +l++l  ++++++ ++ +f+ la++ +
      EEA18530.1 189 GDAAEHLLPRFRNDSPYRYCDVQDIFDHLKTLYMDENRVVNAKMKLRRLVMREMKFQTFLSQFTLLAQESR 259
                     345556666788888888666666666666666666777899999*********************99887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (264 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1275  (0.0711138); expected 358.6 (0.02)
Passed bias filter:                      563  (0.0314016); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.40
# Mc/sec: 1984.47
//
Query:       EEA18531.1  [L=73]
Description: hypothetical protein PMAA_008100 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (73 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       752  (0.0419432); expected 358.6 (0.02)
Passed bias filter:                      462  (0.0257683); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.41
# Mc/sec: 528.53
//
Query:       EEA18532.1  [L=175]
Description: hypothetical protein PMAA_008110 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    5.6e-15   55.5   0.1    6.8e-15   55.2   0.1    1.1  1  DDE_Tnp_1_7  Transposase IS4


Domain annotation for each model (and alignments):
>> DDE_Tnp_1_7  Transposase IS4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.2   0.1   3.8e-19   6.8e-15       2      66 ..      89     162 ..      88     174 .. 0.95

  Alignments for each domain:
  == domain 1  score: 55.2 bits;  conditional E-value: 3.8e-19
  DDE_Tnp_1_7   2 pvelFelflpdkilerivkatNayakqk.........kkwleltaeElkaFlGllllmglvrlpsvedyWstkd 66 
                  p+++F+lf+++++++ +++ tN+ya  k         ++w+ +t  ElkaF+G+++ mg  + p+++dyW++++
   EEA18532.1  89 PYQIFSLFFTEDLFKVLADNTNMYAYAKlsknmnphhRNWRSTTPGELKAFVGAQIYMGFTKEPQLKDYWDEEK 162
                  9*********************************************************************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (175 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       357  (0.0199119); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.29s 00:00:00.75 Elapsed: 00:00:00.46
# Mc/sec: 1154.38
//
Query:       EEA18533.1  [L=906]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.6e-11   43.2   0.0    6.1e-11   42.4   0.0    1.3  1  RVT_2      Reverse transcriptase (RNA-dependent DNA polymeras
    9.8e-07   29.0   0.0    2.3e-06   27.8   0.0    1.7  1  rve        Integrase core domain
  ------ inclusion threshold ------
       0.14   12.0   0.0       0.24   11.2   0.0    1.3  1  Arteri_Gl  Arterivirus GL envelope glycoprotein


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.4   0.0     1e-14   6.1e-11       7     179 ..     397     573 ..     393     630 .. 0.80

  Alignments for each domain:
  == domain 1  score: 42.4 bits;  conditional E-value: 1e-14
       RVT_2   7 slPkdrkaigsrWvftkkkddlkevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeee.lvvhqldvdsafLnae..ldeevyvkqPpG 102
                 + P + +  g r+v   k++  +++  k+rlv+q ++ k ++++  + +P i+ +s rL+l + + ++ +  +  dv  a+++++  l+ e y++ Pp 
  EEA18533.1 397 DIPLEARIYGFRFVDEVKNKGTDKAFEKSRLVVQAYNDK-DKEFVLTQSPTIQRSSQRLILCIGTSKDgVRFWIRDVTQAYIQSTtkLNREFYIRIPPE 494
                 568889999*********9999**************987.567999*****************876651556677*******987336788******** PP

       RVT_2 103 feidreeekvykLnkslyGlkqapllWnekidk.vLkklgferseaesGly.vrgtgegklivalyvddlliagsdiki 179
                         +  ++ + lyG+  a+  W+++ ++   ++lg+e s+    l  +    +g  ++++  dd li++++   
  EEA18533.1 495 LRHYFPGCEFLRVVRPLYGIPEAGNHWFRTYHEhHTTHLGMETSTYDPCLLhCCDPKQGFGVIGMQTDDTLIVADEAFA 573
                 **99888999*****************99887615678899999998876515555666689**********9987644 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0   3.8e-10   2.3e-06       6     117 ..      34     138 ..      29     140 .. 0.78

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 3.8e-10
         rve   6 elwqvDvtvvripdgggkayllvvvddfsrlilaealsdem..dastvlalleravarfggvepervlsDngseytskafrefladlgirvsftrpgrp 102
                 + + vD+++++    g  + +l++vd ++r+  a+ l + +  ++ ++l++l+  ++ + g  p+ +++D g+ ++sk+f+ ++++lg+     ++   
  EEA18533.1  34 HSIIVDIMYIN----G--KPVLHIVDEATRFNAACWLISISarATWDALRMLW--IDTYLGP-PDFIVTDAGKNFVSKEFTHLASSLGTITVSVPVEAH 123
                 56668888888....4..5688999**99997666555552004444444444..6666666.**************************999999999* PP

         rve 103 qdnGkvErfhrtlkd 117
                 ++ G vEr h  l++
  EEA18533.1 124 WSIGAVERYHAVLRR 138
                 **********99987 PP

>> Arteri_Gl  Arterivirus GL envelope glycoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   4.1e-05      0.24      67     150 ..      33     116 ..      30     120 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 4.1e-05
   Arteri_Gl  67 nvaalsytgyvhvryvlssayaalalvAlvlgvysfvvraarlrlclagryaitahtnfvldakGrifrsksqv.vvekpgkteV 150
                 n ++++ ++y+ ++ vl ++  a  + A  +  +s+  ra    l +++    + +++f+++++G++f+sk+   +++ +g ++V
  EEA18533.1  33 NHSIIVDIMYINGKPVLHIVDEATRFNAACW-LISISARATWDALRMLWIDTYLGPPDFIVTDAGKNFVSKEFThLASSLGTITV 116
                 5677788999999999999999*********.44466666655788*********************999988878888888777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (906 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       460  (0.0256568); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.70u 0.30s 00:00:01.00 Elapsed: 00:00:00.48
# Mc/sec: 5641.81
//
Query:       EEA18534.1  [L=794]
Description: hypothetical protein PMAA_008130 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.057   13.6   0.6        0.3   11.3   0.0    2.5  3  PAC4      Proteasome assembly chaperone 4


Domain annotation for each model (and alignments):
>> PAC4  Proteasome assembly chaperone 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.1      0.66   1.2e+04      33      56 ..     199     220 ..     185     225 .. 0.65
   2 ?   -2.1   0.0      0.26   4.7e+03      26      42 ..     356     380 ..     340     395 .. 0.67
   3 ?   11.3   0.0   1.7e-05       0.3      32      70 ..     544     584 ..     519     587 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 0.66
        PAC4  33 vAmpsrtnkktptisTtLlgdg.sd 56 
                  A+ srt   +  ++T+L g + s+
  EEA18534.1 199 PALASRTT--VG-TTTQLQGIPeSQ 220
                 46666666..22.577777666554 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.26
        PAC4  26 s........plgslvvAmpsrtnkk 42 
                 +        +l++l +++p+  + +
  EEA18534.1 356 HecldlmlvKLQDLFYCLPDELQTQ 380
                 155555555679999***9998844 PP

  == domain 3  score: 11.3 bits;  conditional E-value: 1.7e-05
        PAC4  32 vvAmpsrtnkktptisTtLlgdg.sde..aserlAqrLArRl 70 
                  +++p+rt+ + pt++T  ++   +d   +s++lA+ LA R 
  EEA18534.1 544 QYSLPDRTK-NEPTTATGYFTVAaTDHneFSSSLASELANRS 584
                 69******9.7799999999777553355**********995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (794 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       601  (0.0335211); expected 358.6 (0.02)
Passed bias filter:                      434  (0.0242066); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 5276.29
//
Query:       EEA18535.1  [L=341]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.2e-28   97.7   0.0    1.9e-27   96.5   0.0    1.6  1  DDE_Tnp_1_7      Transposase IS4
    2.7e-12   47.2   9.4    7.3e-12   45.9   9.4    1.8  1  Tnp_zf-ribbon_2  DDE_Tnp_1-like zinc-ribbon


Domain annotation for each model (and alignments):
>> DDE_Tnp_1_7  Transposase IS4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   96.5   0.0   2.1e-31   1.9e-27     147     350 .]       1     232 [.       1     232 [. 0.87

  Alignments for each domain:
  == domain 1  score: 96.5 bits;  conditional E-value: 2.1e-31
  DDE_Tnp_1_7 147 lpgkprkvgiklhvlcdsqtgyilalelyegearnlrl..srelgktnalvlrLleplqgkg..rvvvmdnfftslellqeLakkgtyavGtlkknrs 240
                  +p+kp   g+k++vl+d   gy + +++  ++++ ++    +el+kt ++v +L+++l + +  + +++dn+fts++l+++L++ ++ a+Gt +  ++
   EEA18535.1   1 MPNKPISQGFKIFVLAD--HGYCYYFYPASRTKGVVEVgmAKELTKTGQMVYELVQTLPKDNktYDLYLDNYFTSVNLFKALREIQVGACGTTRP-HK 95 
                  699**************..9**********999877653378****************965555*******************************.77 PP

  DDE_Tnp_1_7 241 glPkeltqklpkgellaryg......gplmllkwndrkkvkllstyss....qklveskersg................qki..karpklvedYnqal 310
                  ++P+ l++ ++ g+   +++      +++  ++w d++ v+ l+t+++    ++ +e+ +r+                 q +     p  ++dYn ++
   EEA18535.1  96 EFPNLLKKLKDLGSYIPYHKvcaipvNDVLCVAWQDNNIVLALTTIHTvdqtDDYIERTRRRPqktstngplvhkefgeQAVknMPIPRFIDDYNSHM 193
                  ***88876666666666666666666**********************876555588777775677888899999998844543479*********** PP

  DDE_Tnp_1_7 311 gavdrhdqllqayraslktskkwykrvlifllsiavvNAy 350
                  g+vd ++q ++ y  ++k+ ++w+  +   +l++ +vNAy
   EEA18535.1 194 GGVDIANQHRAVYDTHIKAFRSWWP-LWNWCLDVGIVNAY 232
                  ************************9.*************9 PP

>> Tnp_zf-ribbon_2  DDE_Tnp_1-like zinc-ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.9   9.4   8.1e-16   7.3e-12       1      31 []     293     334 ..     293     341 .] 0.94

  Alignments for each domain:
  == domain 1  score: 45.9 bits;  conditional E-value: 8.1e-16
  Tnp_zf-ribbon_2   1 kRCkvClkkkikke.......TriiCqeCdvplCrnh....C 31 
                      kRC++Cl+k++k++       T++iCq+CdvplCr++    C
       EEA18535.1 293 KRCIWCLYKNPKRQtgqspsfTTFICQACDVPLCRPEtgrtC 334
                      8**********************************9877776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (341 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       469  (0.0261587); expected 358.6 (0.02)
Passed bias filter:                      367  (0.0204696); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2329.98
//
Query:       EEA18536.1  [L=394]
Description: aspergillopepsin A precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.5e-53  180.7   0.0    5.3e-53  180.5   0.0    1.0  1  Asp             Eukaryotic aspartyl protease
    2.3e-06   28.1   0.0     0.0078   16.8   0.0    2.7  2  Asp_protease_2  Aspartyl protease
     0.0014   18.9   0.0        3.1    8.0   0.0    3.0  3  TAXi_N          Xylanase inhibitor N-terminal
  ------ inclusion threshold ------
      0.034   12.4   0.0      0.061   11.6   0.0    1.3  1  Pox_P4B         Poxvirus P4B major core protein


Domain annotation for each model (and alignments):
>> Asp  Eukaryotic aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  180.5   0.0   1.2e-56   5.3e-53       1     314 [.      83     392 ..      83     393 .. 0.89

  Alignments for each domain:
  == domain 1  score: 180.5 bits;  conditional E-value: 1.2e-56
                 EEEEEEEETTTTEEEEEEEETT--SEEEEBTTESTSHCHHTSS-B-GGG-TT-EEEEEEEEEECTTS.EEEEEEEEEEEEETTEEEEEEEEEEEEEESS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp   1 eYfgeisiGtpeqkftvifDTGSsdlWVpsskckkssackshstydpskSstykkngkslsisYGdg.svsGflsqdtvkvggltvknqefgeatkepg 98 
                 eY+++i+iG +   ++v +DTGSs+lW    ++     + +h +y+p+    +   g++++   Gd+ +++G ++qd v++g l+ +nq+++ ++  + 
  EEA18536.1  83 EYLTPIQIGDN--ILKVCLDTGSSNLWAYTPQTP---RVGFHAKYNPKT--GRLMPGYDWYTINGDQtTLRGRVFQDIVNIGHLSYPNQAVQVVDIITP 174
                 6********99..89************9988876...799*******95..55679****88889999*************************998777 PP

                 HHHTTSS...SSEEEE-S-GGGSCGG...SCCHHHHHHHTTSSSSSEEEEEE-STTSSEEEEEESSEEGGGEEEEEEEEEESS.TSSTEEEEEEEEETT CS
                 xxxxxxx...xxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxx RF
         Asp  99 stflaak...fdGiLGlgfkeisvee...atpvfdnlvsqglikepvfsvylnreeeeggeivfGgvDeskykGsltyvpvts.kgywqielesvtvgg 190
                 +++++ +    dGi+G++f++++ ++   ++++f n++  + +++p+f++ l   +++ g++ fG +D++kykG+++++ v++ +g w+i+++++ +g 
  EEA18536.1 175 QSAMYNPsraHDGIFGMAFSSLNCVRprkQKTFFANIK--RFLNSPLFAFCLK--HRTPGTVDFGWIDPKKYKGQIFWTHVDKsEGLWKISIDGFRIGR 269
                 77776554569*************998888999***75..57**********5..9*************************998999************ PP

                 EEEEEEEEEEEEEETTCSSEEEEHHHHHHHHHHHTTEEE.ETTCEEEEETTGGGGSEEEEEEETTEEEEEEGGGGEEEESSSTTSEEEESEEECCTSSS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp 191 ktvlcssgcqailDtGTsllalptsivekiakaigakks.esegeyvvdCdslsslpdisftiggakitvpvselvlkeeeseesqCilglvseeegdl 288
                 + + +  +++ai+DtG s+  +p+ +v+++ k i ++++ ++ g y++ C ++s  pd+s++ig++   +p  +l+ ++++  ++ C+ g++s+++ +l
  EEA18536.1 270 DHS-SPISFSAIVDTGSSINLFPEYVVKQYYKRIPGSYKsTQDGGYIFPCTQTSVIPDLSLEIGQHIAVIP-GQLLKYSSN--RTHCFGGIQSSPHPSL 364
                 **9.999**************************977655155699*****************876655555.555555543..368************* PP

                 EEEEHHHHTTEEEEE..ETTTTEEEEEE CS
                 xxxxxxxxxxxxxxx..xxxxxxxxxxx RF
         Asp 289 wiLGdvFlrsayvvf..dldnnrvglAe 314
                 ++LGdvFl+  yv+f  d +n  +g+A+
  EEA18536.1 365 NVLGDVFLKGHYVIFfdDSTNPWIGIAP 392
                 ************8876668999999996 PP

>> Asp_protease_2  Aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.0   1.7e-06    0.0078       2      90 .]      87     193 ..      86     193 .. 0.84
   2 !    8.4   0.0   0.00072       3.2      10      34 ..     277     301 ..     259     333 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 1.7e-06
  Asp_protease_2   2 pvtinGkpvrfllDTGasttlispelaeklglkvreseltvrv......sgaggevkarlvrlds..lklggltlknvpalvld..........l 78 
                     p++i++  ++++lDTG+s++   +    + g + + ++ t r+       +++g++++ ++r+ +  +++g l+ +n+++ v+d          +
      EEA18536.1  87 PIQIGDNILKVCLDTGSSNLWAYTPQTPRVGFHAKYNPKTGRLmpgydwYTINGDQTTLRGRVFQdiVNIGHLSYPNQAVQVVDiitpqsamynP 181
                     789999999**********999988888888877777666554333444679******999998888*****************99999998877 PP

  Asp_protease_2  79 geeidglLGmdf 90 
                      + +dg+ Gm f
      EEA18536.1 182 SRAHDGIFGMAF 193
                     7899******87 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.00072
  Asp_protease_2  10 vrfllDTGasttlispelaeklglk 34 
                     +++++DTG+s +l ++ ++++   +
      EEA18536.1 277 FSAIVDTGSSINLFPEYVVKQYYKR 301
                     699**********999999887554 PP

>> TAXi_N  Xylanase inhibitor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   0.0    0.0007       3.1       1      29 [.      84     110 ..      84     134 .. 0.74
   2 !    6.4   0.0    0.0022       9.8      85     177 ..     139     235 ..     131     235 .. 0.76
   3 ?    0.4   0.0      0.15   6.5e+02      10      24 ..     273     287 ..     266     301 .. 0.87

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0007
      TAXi_N   1 YlvsisiGtppqplklvvDtGsdltWvqC 29 
                 Yl+ i+iG +   lk+ +DtGs+ +W   
  EEA18536.1  84 YLTPIQIGDN--ILKVCLDTGSSNLWAYT 110
                 9999****98..899***********876 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.0022
      TAXi_N  85 ygadgssssGvlatdtltlsstdgksvkvpnlvfGCgksnlgglaagadGilGLGrgklSlvsqlaskg........slgnkFsyCLssssssssgvlf 175
                 +  d+++ +G + +d + +   + +++ v+ + +   +s   +  +  dGi G+++++l  v   ++k+          +  F+ CL   + + +g + 
  EEA18536.1 139 N-GDQTTLRGRVFQDIVNIGHLSYPNQAVQVVDIITPQSAMYNPSRAHDGIFGMAFSSLNCVRPRKQKTffanikrfLNSPLFAFCL---KHRTPGTVD 233
                 4.4888999**********88877888888777777776777777789***********9999999888777665444456799999...666666666 PP

      TAXi_N 176 fG 177
                 fG
  EEA18536.1 234 FG 235
                 65 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.15
      TAXi_N  10 ppqplklvvDtGsdl 24 
                  p +++++vDtGs++
  EEA18536.1 273 SPISFSAIVDTGSSI 287
                 567899*******86 PP

>> Pox_P4B  Poxvirus P4B major core protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   1.4e-05     0.061     494     555 ..     321     388 ..     306     390 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 1.4e-05
     Pox_P4B 494 rslindsPidvsqei.vlnGilyrlksavcykvgdqlidncdsa.....diflkGyytilftel.GPwl 555
                  s+i d  +++ q+i v+ G l +  s   +  g   +     +     d+flkG+y i+f +   Pw+
  EEA18536.1 321 TSVIPDLSLEIGQHIaVIPGQLLKYSSNRTHCFGGIQSSPHP-SlnvlgDVFLKGHYVIFFDDStNPWI 388
                 699**********99457898877777665555552222222.123468************98526996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (394 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       301  (0.0167884); expected 358.6 (0.02)
Passed bias filter:                      289  (0.0161191); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 2599.49
//
Query:       EEA18537.1  [L=1583]
Description: hypothetical protein PMAA_008160 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.7e-39  135.3   0.0    4.8e-39  134.4   0.0    1.4  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    3.9e-06   27.0   0.1    1.6e-05   25.0   0.1    2.0  1  rve              Integrase core domain
    0.00026   20.8   0.1    0.00058   19.7   0.1    1.6  1  gag_pre-integrs  GAG-pre-integrase domain


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  134.4   0.0   8.1e-43   4.8e-39       2     241 ..    1099    1335 ..    1098    1336 .. 0.93

  Alignments for each domain:
  == domain 1  score: 134.4 bits;  conditional E-value: 8.1e-43
       RVT_2    2 tyrlvslPkdrkaigsrWvftkkkddl.kevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeeelvvhqldvdsafLnaeldeevyv 97  
                  t++ v  P++ + ++ +Wvf+ k d+  k +k+kar+ ++G  q a++    + a  +     r++++laa+ +l + q+d   af+n+elde+vy 
  EEA18537.1 1099 TFEFVPRPRNIQILPLTWVFKYKFDKHgKLAKFKARICVRGDLQDANK--LPTRAATLASRNFRMMMSLAAVFDLEIVQFDAVNAFVNSELDEDVYT 1193
                  7999*******************9999899****************97..567777888889*********************************** PP

       RVT_2   98 kqPpGfeidreeekvykLnkslyGlkqapllWnekidkvLkklgferseaesGlyvrgtgegklivalyvddlli...agsdikiledvkkelakkf 191 
                    P Gf      +kv+kL+++lyGl+++p+lW+ +++++L  lgf++++ e+ l+v++     +i+  +vdd+l+    g+++ ++e++ k l+  +
  EEA18537.1 1194 YFPDGFREA---GKVMKLKRALYGLRRSPRLWQLELTRTLLGLGFSQIPDEECLFVKN----GVILLFFVDDILVfydKGQKQAEFEEIEKGLNDAY 1283
                  ******755...********************************************98....788899******94444788999************ PP

       RVT_2  192 klkdlgkvskfLGieiaq..eaggiklsladyiakvvkkfeltdaktvatPl 241 
                  +l+++ k + fL i i++   + +i l++  yi k+++ f+ +++k++ tP+
  EEA18537.1 1284 ELRKMDKFEWFLNIRITRdrAQRKIWLCQDSYIIKIAERFKCNTTKPILTPI 1335
                  ****************99434567899************************8 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.0   0.1   2.7e-09   1.6e-05       4     115 ..     571     680 ..     568     683 .. 0.85

  Alignments for each domain:
  == domain 1  score: 25.0 bits;  conditional E-value: 2.7e-09
         rve   4 pgelwqvDvtvvripdgggkayllvvvddfsrlilaealsdemdastvlalleravarfggvepervlsDngseytskafrefladlgirvsftrpgrp 102
                 + + + vD+ v+      ++ y l++v  f ++     +++++  +++ a++e+    f    +e+v++D  s+    afr++++  ++ + +t p  p
  EEA18537.1 571 AFHTLFVDIIVMT-QAITREQYALHAVYPFAKFHALATVDSKAVVADMKAIIEKIEHTFRTH-VEVVHTDGESSLNGLAFRTWCNGRHTLLYMTVPNTP 667
                 5566788888666.444557999999999999999999999988888888888777777776.************************************ PP

         rve 103 qdnGkvErfhrtl 115
                 ++nG  Er+ +++
  EEA18537.1 668 EQNGPSERAGGLI 680
                 ********87776 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.1   9.8e-08   0.00058       2      64 ..     478     553 ..     477     554 .. 0.70

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 9.8e-08
  gag_pre-integrs   2 LYlldlssnanssv.........slskn..kssinlWHrRLGHpsfsrlkkLfkkgl.lpglkisk.sevCeaCql 64 
                      LY ++++  ++s+          s++k+  k+s+  WH+R GH  +++ +  +   + l+g+++++ +e+Ce+C++
       EEA18537.1 478 LYFVKWNAKPSSNPplrnelafsSFEKTtlKDSALAWHKRYGHKLEDATEGAIVTTSeLHGKNEDDlQEKCEICAM 553
                      8999998666643322333322256665678*************9999988775433488888777578*****85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1583 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       905  (0.0504769); expected 358.6 (0.02)
Passed bias filter:                      488  (0.0272185); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.96u 0.30s 00:00:01.26 Elapsed: 00:00:00.48
# Mc/sec: 9982.32
//
Query:       EEA18538.1  [L=392]
Description: aspergillopepsin A precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.4e-55  189.0   0.2    1.6e-55  188.7   0.2    1.1  1  Asp              Eukaryotic aspartyl protease
    1.9e-05   25.2   0.2     0.0035   18.0   0.0    2.8  2  Asp_protease_2   Aspartyl protease
    8.8e-05   22.8   0.0       0.53   10.5   0.0    3.2  4  TAXi_N           Xylanase inhibitor N-terminal
  ------ inclusion threshold ------
      0.083   13.5   0.0        3.8    8.1   0.0    2.8  2  gag-asp_proteas  gag-polyprotein putative aspartyl protease


Domain annotation for each model (and alignments):
>> Asp  Eukaryotic aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  188.7   0.2   3.6e-59   1.6e-55       2     314 ..      86     390 ..      85     391 .. 0.91

  Alignments for each domain:
  == domain 1  score: 188.7 bits;  conditional E-value: 3.6e-59
                 EEEEEEETTTTEEEEEEEETT--SEEEEBTTESTSHCHHTSS-B-GGG-TT-EEEEEEEEEECTTS.EEEEEEEEEEEEETTEEEEEEEEEEEEEESSH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp   2 YfgeisiGtpeqkftvifDTGSsdlWVpsskckkssackshstydpskSstykkngkslsisYGdg.svsGflsqdtvkvggltvknqefgeatkepgs 99 
                 Y+++i++G +  ++ v fDTGSs+lWV  s++         stydps  +     +++++i+YGdg +v G ++ d+v vg++  +nq+++ a+  +++
  EEA18538.1  86 YLSPIKVGNN--ELLVEFDTGSSELWVKTSESP----GAGPSTYDPSTGTL--LPNYHWHIEYGDGsTVGGKVYIDEVMVGNIRSHNQAIEIADYINAP 176
                 999*****99..8***************99998....68999***976655..589**********99******************************* PP

                 HHTTSSSSEEEE-S-GGGSCGG...SCCHHHHHHHTTSSSSSEEEEEE-STTSSEEEEEESSEEGGGEEEEEEEEEESS.TSSTEEEEEEEEETTEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxx RF
         Asp 100 tflaakfdGiLGlgfkeisvee...atpvfdnlvsqglikepvfsvylnreeeeggeivfGgvDeskykGsltyvpvts.kgywqielesvtvggktvl 194
                  +l   +dGi+Glgf +++ ++   + ++f+n+++   +++pvf+ yl   + + g+  fG+++++ky+G++tyv+v++ +gyw+i+ ++++vg   + 
  EEA18538.1 177 EILRDVIDGIMGLGFFKLNKVQpipQLTFFENVKAS--LDTPVFAAYLR--HLAPGSFDFGYINPQKYTGTITYVDVDHsQGYWNITWDGFSVGPIYS- 270
                 **************9999999967777779997765..**********5..99************************9889**************999. PP

                 EEEEEEEEEETTCSSEEEEHHHHHHHHHHHTTEEEET.TCEEEEETTGGGGSEEEEEEETTEEEEEEGGGGEEEESSSTTSEEEESEEECCTSSSEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp 195 cssgcqailDtGTsllalptsivekiakaigakkses.egeyvvdCdslsslpdisftiggakitvpvselvlkeeeseesqCilglvseeegdlwiLG 292
                     +++i+DtGTsll l++ iv k+ ++i +++  + +g +v+dC +  +lp++s++ig  +  v ++ l + +  +  + C+ g++ + ++ + iLG
  EEA18538.1 271 AVYPFHVIVDTGTSLLLLDDFIVGKYYTHITTAYYAYqHGGWVFDCRE--DLPYLSLKIGAYEAFVLPEYLKYADLGG--NVCYGGIQRTIHEGYSILG 365
                 8899*********************9988876665542699******8..****************999988887754..69***************** PP

                 HHHHTTEEEEEE...TTTTEEEEEE CS
                 xxxxxxxxxxxx...xxxxxxxxxx RF
         Asp 293 dvFlrsayvvfd...ldnnrvglAe 314
                  +Fl+  yv+fd   ++  +vg+A+
  EEA18538.1 366 TIFLKTQYVIFDdgtTGSPQVGFAK 390
                 ************5555678999997 PP

>> Asp_protease_2  Aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   7.7e-07    0.0035       2      90 .]      89     191 ..      88     191 .. 0.82
   2 ?    4.0   0.0     0.017        78       9      24 ..     274     289 ..     261     300 .. 0.89

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 7.7e-07
  Asp_protease_2   2 pvtinGkpvrfllDTGasttlispelaeklglkvreseltvrvsg.......aggevkarlvrldslklggltlknvpalvld.......lgeei 82 
                     p+++++ ++ + +DTG+s + + ++    +g ++++ ++ +++          +g++ + +v +d++ +g+++ +n+++ ++d       l + i
      EEA18538.1  89 PIKVGNNELLVEFDTGSSELWVKTSESPGAGPSTYDPSTGTLLPNyhwhieyGDGSTVGGKVYIDEVMVGNIRSHNQAIEIADyinapeiLRDVI 183
                     688999999999***************9999877765533332222333333899*****************************99988888999 PP

  Asp_protease_2  83 dglLGmdf 90 
                     dg++G+ f
      EEA18538.1 184 DGIMGLGF 191
                     ****9865 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.017
  Asp_protease_2   9 pvrfllDTGasttlis 24 
                     p+++++DTG s +l++
      EEA18538.1 274 PFHVIVDTGTSLLLLD 289
                     7899*******99987 PP

>> TAXi_N  Xylanase inhibitor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       1.1     5e+03      83     109 ..      43      68 ..      15      76 .. 0.73
   2 !   10.5   0.0   0.00012      0.53       1      30 [.      86     113 ..      86     133 .. 0.81
   3 !    8.2   0.0   0.00061       2.7      80     146 ..     135     197 ..     125     213 .. 0.77
   4 ?   -1.1   0.0      0.42   1.9e+03      13      26 ..     274     287 ..     270     290 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 1.1
      TAXi_N  83 isygadgssssGvlatdtltlsstdgk 109
                 ++y+ + +++ Gv++ d +tl   +g+
  EEA18538.1  43 AKYA-RAHTKYGVYIPDYITLAARSGN 68 
                 5664.6667889999999998777664 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00012
      TAXi_N   1 YlvsisiGtppqplklvvDtGsdltWvqCk 30 
                 Yl  i++G++  +l++ +DtGs+ +Wv+ +
  EEA18538.1  86 YLSPIKVGNN--ELLVEFDTGSSELWVKTS 113
                 8899999998..9**************983 PP

  == domain 3  score: 8.2 bits;  conditional E-value: 0.00061
      TAXi_N  80 eyeisygadgssssGvlatdtltlsstdgksvkvpnlvfGCgk..snlgglaagadGilGLGrgklSlv 146
                 + +i+yg dgs++ G++  d++ + ++     + +n ++  ++  +  + l++  dGi+GLG+ kl  v
  EEA18538.1 135 HWHIEYG-DGSTVGGKVYIDEVMVGNI-----RSHNQAIEIADyiNAPEILRDVIDGIMGLGFFKLNKV 197
                 56899*7.****************555.....55555555544456778888899*******9887655 PP

  == domain 4  score: -1.1 bits;  conditional E-value: 0.42
      TAXi_N  13 plklvvDtGsdltW 26 
                 p+ ++vDtG +l+ 
  EEA18538.1 274 PFHVIVDTGTSLLL 287
                 789******99986 PP

>> gag-asp_proteas  gag-polyprotein putative aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.0   0.00086       3.8       4      78 ..      91     172 ..      88     193 .. 0.64
   2 ?    2.0   0.0     0.068     3e+02       9      23 ..     274     288 ..     271     296 .. 0.84

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00086
                      EETTEEEEEEEETT-SS-EEEHHHHHHTTGGGGEB..TT--........EE-TTSTT-EEEEEEEEEE.EETTEEEEEEEEEE CS
  gag-asp_proteas   4 kingkpvkflvDTGAsstiiseelaerlglsrkedkgkvev........ktangeveakrvrldsvkiggielrnvsavvleg 78 
                      k+ ++++ + +DTG s+  ++++    +g s+ + ++++++        + ++g++ +++v++d+v +g+i+ +n  + +++ 
       EEA18538.1  91 KVGNNELLVEFDTGSSELWVKTSESPGAGPSTYD-PSTGTLlpnyhwhiEYGDGSTVGGKVYIDEVMVGNIRSHNQAIEIADY 172
                      5666666666777777777777777777644443.33333334444444788999999****************988777653 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.068
                      EEEEEEETT-SS-EE CS
  gag-asp_proteas   9 pvkflvDTGAsstii 23 
                      p++++vDTG s  ++
       EEA18538.1 274 PFHVIVDTGTSLLLL 288
                      899******987665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (392 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       355  (0.0198003); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 2789.37
//
Query:       EEA18539.1  [L=456]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-29  103.5   0.4    2.6e-29  102.6   0.1    1.6  2  RVT_2     Reverse transcriptase (RNA-dependent DNA polymerase
     0.0094   15.5   0.0      0.017   14.7   0.0    1.3  1  RVT_1     Reverse transcriptase (RNA-dependent DNA polymerase
  ------ inclusion threshold ------
       0.02   14.8   0.0      0.042   13.7   0.0    1.6  1  Flg_hook  Flagellar hook-length control protein FliK


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.6   0.1   4.3e-33   2.6e-29      52     234 ..       3     182 ..       1     188 [. 0.91
   2 ?   -2.3   0.0      0.48   2.8e+03      14      61 ..     376     425 ..     372     431 .. 0.73

  Alignments for each domain:
  == domain 1  score: 102.6 bits;  conditional E-value: 4.3e-33
       RVT_2  52 evfaPvirldsvrLllalaaeeelvvhqldvdsafLnaeldeevyvkqPpGfeidreeekvykLnkslyGlkqapllWnekidkvLkklgferseaesG 150
                 +++a  +   s r ++a+aa  +l + q d   af+naeldee++++  p +    e++k+y+Lnk+lyGl+++pllW+++++++L klgf+  + e  
  EEA18539.1   3 DTYAATLAARSFRTFMAIAARFDLELKQYDAVNAFVNAELDEEIFMRMAPRYR---ESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFKAVPHEPC 98 
                 677777888999************************************99885...57****************************************9 PP

       RVT_2 151 lyvrgtgegklivalyvddlliagsdikiled..vkkelakkfklkdlgkvskfLGieiaq..eaggiklsladyiakvvkkfeltda 234
                   +++     +++  yvdd+++a ++++ le   + ++l +k++++   +++ fLG+ i++  ++  i ls+a yi k++k ++ ++a
  EEA18539.1  99 CMLKS----GVMLFFYVDDIVVAYKKSRQLEAnlILNQLRAKYNISRGEDLEWFLGMRIIRdrSNKMIWLSQATYIDKIAKLADTQQA 182
                 99999....78999**********9999886533889**********************986568889***********998876655 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 0.48
       RVT_2  14 aigsrWvftkkkddlkevkyk..arlvaqGfsqkagedydevfaPvirld 61 
                  i ++Wv +  ++  ++v+y     ++a+G ++  + + +++f   ir+d
  EEA18539.1 376 DIHNHWVRQEVQNGDVQVHYMptKDMIANGLTKALNRQEHHIFLKQIRVD 425
                 57889999999998899998622457888888887777777777666666 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   2.8e-06     0.017     121     184 ..      55     128 ..      21     139 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 2.8e-06
                 ...TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T................TEEECTTEEEEEESSHHHHHHHH CS
       RVT_1 121 eeskgryekkglpqGsvlSPllfnlfmnellrelrkra..........kgvtllrYaDDililskskeelqell 184
                 +es+++y+ +    G+  SPll++  +++ l +l  +a          +gv l  Y+DDi++++k+  +l++ l
  EEA18539.1  55 RESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFKAvphepccmlkSGVMLFFYVDDIVVAYKKSRQLEANL 128
                 46789999999999***********999999999988899**************************99977654 PP

>> Flg_hook  Flagellar hook-length control protein FliK
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0     7e-06     0.042      33      69 ..     341     377 ..     334     394 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 7e-06
                 EETTEEEEEEEE-SCHHHHHHHHTHHHHHHHHHCCTT CS
    Flg_hook  33 lrggqlsvqltaenpetrelLeqnlprLreaLaaaGl 69 
                 +r +  ++++  +n++t+ lLe+++prLr+ L+   +
  EEA18539.1 341 IRFQTPTLHVYCDNQQTLGLLEKDAPRLRTKLRHVDI 377
                 555566899***********************87544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (456 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       441  (0.024597); expected 358.6 (0.02)
Passed bias filter:                      355  (0.0198003); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 3086.85
//
Query:       EEA18540.1  [L=793]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.1e-07   29.5   0.0    1.3e-06   28.1   0.0    1.7  2  gag_pre-integrs  GAG-pre-integrase domain
     0.0016   18.7   0.0     0.0029   17.8   0.0    1.5  1  rve              Integrase core domain
  ------ inclusion threshold ------
      0.035   14.4   2.1      0.073   13.4   2.1    1.5  1  Orthopox_F14     Orthopoxvirus F14 protein


Domain annotation for each model (and alignments):
>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.1   0.0   2.2e-10   1.3e-06      19      66 ..     163     214 ..     146     215 .. 0.74
   2 ?   -3.7   0.0       1.9   1.1e+04      31      44 ..     478     491 ..     478     495 .. 0.82

  Alignments for each domain:
  == domain 1  score: 28.1 bits;  conditional E-value: 2.2e-10
  gag_pre-integrs  19 knkssinlWHrRLGHpsfsrlkkLfkkgl...lpglkisk...sevCeaCqlgK 66 
                        k ++n+WH RLGHp+ + lk L+       l ++  sk     +Ce+C  +K
       EEA18540.1 163 ERKADANRWHARLGHPGPEVLKYLAGAAKgvrLTRI--SKgptTVECESCGTSK 214
                      35899********************85443234444..44333559****9988 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 1.9
  gag_pre-integrs  31 LGHpsfsrlkkLfk 44 
                      L H+s + +++L  
       EEA18540.1 478 LLHVSTQEITRLLT 491
                      569****9999975 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   4.9e-07    0.0029       3     116 ..     229     344 ..     227     346 .. 0.84

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 4.9e-07
         rve   3 rpgelwqvDvtvvripdgggkayllvvvddfsrlilaealsdemdastvlalleravarfggve...pervlsDngseytskafrefla.dlgirvsft 97 
                 +pge++ +D+  ++ ++  g++ l  ++d fs++++ ++++++   + +l++l+ +++++ +     p ++ +Dn  + +  +++ +l+ + +i ++++
  EEA18540.1 229 APGEHLAIDFHDFAESTMYGEKTLMLITDRFSGFMWDYYMTSH-RGDEILETLKWFLDYLEKAYmisPVKIEMDNKIAKRP-EVKHYLEhEKRIILQPS 325
                 79*********666566777***********************.**********99999999879**********976664.55555541578999999 PP

         rve  98 rpgrpqdnGkvErfhrtlk 116
                 +++    nG +Er   ++k
  EEA18540.1 326 PAHTQALNGGAERSGAIIK 344
                 9999999999999876666 PP

>> Orthopox_F14  Orthopoxvirus F14 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   2.1   1.2e-05     0.073      32      72 ..     481     520 ..     468     521 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 1.2e-05
  Orthopox_F14  32 idedditellniltelGcdvdfdedfsdiaddvleslieqd 72 
                   +  ++it ll  l +lG d dfd++++d+ d +++ +++ d
    EEA18540.1 481 VSTQEITRLLTKL-DLGTDADFDNEYADLIDHMMDVVFDGD 520
                   5667888888776.79****************999877655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (793 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       462  (0.0257683); expected 358.6 (0.02)
Passed bias filter:                      437  (0.0243739); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.26s 00:00:00.88 Elapsed: 00:00:00.42
# Mc/sec: 5679.87
//
Query:       EEA18541.1  [L=455]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.21   12.0   3.2         11    6.5   0.2    2.5  2  REV1_C    DNA repair protein REV1 C-terminal domain


Domain annotation for each model (and alignments):
>> REV1_C  DNA repair protein REV1 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.3    0.0012        21      44      82 ..     148     186 ..     128     189 .. 0.84
   2 ?    6.5   0.2   0.00063        11      17      81 ..     207     269 ..     199     278 .. 0.84

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0012
      REV1_C  44 vavlkwlrvlleeeeeskeeeageaWekafrevkeavqe 82 
                 +++  w+++ +  + +++   ++ +W++a+ ++ke+v++
  EEA18541.1 148 EQIFIWMKQTVSPSYHKTCIAVTANWKEAYINLKEQVNQ 186
                 5677799999998888999999***************96 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.00063
      REV1_C  17 gPneeDvealakyLkkvv..eeerdlekavavlkwlrvlleeeeeskeeeageaWekafre.vkeavq 81 
                 +P  +D+ea     ++++  +e + +  a +vl w  + l+       +  ++aW +a++  ++e+++
  EEA18541.1 207 KPSTRDLEAWIIKWEELLleAERKSMVIADDVLDWSTRFLDAI-----RPLDNAWTTAYEItIEEKIE 269
                 799999999888888888788889******************9.....9**********853666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (455 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1138  (0.0634726); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.41
# Mc/sec: 3295.05
//
Query:       EEA18542.1  [L=428]
Description: hypothetical protein PMAA_008210 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (428 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       522  (0.0291148); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.39
# Mc/sec: 3322.97
//
Query:       EEA18543.1  [L=318]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (318 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       403  (0.0224776); expected 358.6 (0.02)
Passed bias filter:                      244  (0.0136092); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.20s 00:00:00.64 Elapsed: 00:00:00.37
# Mc/sec: 2556.34
//
Query:       EEA18544.1  [L=204]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (204 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       491  (0.0273858); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.24s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1533.22
//
Query:       EEA18545.1  [L=132]
Description: hypothetical protein PMAA_008240 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (132 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       365  (0.0203581); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.23s 00:00:00.61 Elapsed: 00:00:00.39
# Mc/sec: 1019.66
//
Query:       EEA18546.1  [L=199]
Description: hypothetical protein PMAA_008250 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.023   14.9   0.3       0.69   10.2   0.1    2.1  2  WXG100    Proteins of 100 residues with WXG


Domain annotation for each model (and alignments):
>> WXG100  Proteins of 100 residues with WXG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.0    0.0068   1.2e+02      36      60 ..      77     100 ..      57     116 .. 0.60
   2 ?   10.2   0.1   3.8e-05      0.69      15      62 ..     136     185 ..     125     195 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.0068
                 HCGCGCTHHHCHHHHHHHHHHHHHH CS
      WXG100  36 alqsgWsGaaadafqaefeewkqaa 60 
                 al ++W Gaa  +f++e   + +++
  EEA18546.1  77 ALYQQWHGAAM-EFFKEVRHLEASF 100
                 34568888664.4555555555555 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 3.8e-05
                 HHHHHHHHHHHHHHHHHHHHHHCGCGCT..HHHCHHHHHHHHHHHHHHHH CS
      WXG100  15 rfqkqaeeledelqrlkaevdalqsgWs..Gaaadafqaefeewkqaaqk 62 
                 r+++ +++ + + q+ +  +++lq+ W+    a+++f+a+ ++++q+ ++
  EEA18546.1 136 RLDRFHKRYHRARQSYDDGLAQLQDHWKsiERARTRFEAQPDRIDQEYRQ 185
                 67788889999999999999999999998889999999999999998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (199 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       604  (0.0336884); expected 358.6 (0.02)
Passed bias filter:                      492  (0.0274416); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1337.04
//
Query:       EEA18547.1  [L=113]
Description: hypothetical protein PMAA_008260 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (113 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       288  (0.0160634); expected 358.6 (0.02)
Passed bias filter:                      206  (0.0114898); expected 358.6 (0.02)
Passed Vit filter:                         8  (0.000446204); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.37u 0.27s 00:00:00.64 Elapsed: 00:00:00.42
# Mc/sec: 802.22
//
Query:       EEA18548.1  [L=365]
Description: pogo transposable element, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      5e-31  107.7   0.0    7.6e-31  107.1   0.0    1.3  1  DDE_1        DDE superfamily endonuclease
      7e-06   26.0   0.0    1.5e-05   24.9   0.0    1.6  1  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
    0.00013   21.7   0.0    0.00053   19.8   0.0    1.9  2  DDE_3        DDE superfamily endonuclease


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  107.1   0.0   1.3e-34   7.6e-31       2     175 .]     116     285 ..     115     285 .. 0.93

  Alignments for each domain:
  == domain 1  score: 107.1 bits;  conditional E-value: 1.3e-34
       DDE_1   2 erltvllcanaagsekLkplvigkaksp.rafkngektkkkldveyksnrkawltssifeeWL.kvfdkrle..aekrkilLlldssrshetvel.les 95 
                 ++++++++a+ +++  L+++vi+ka+++ ++ ++   ++ + d +  +++++w+t++i+ +WL k+f++ +    ++r+ +L+ld+++sh t+++   +
  EEA18548.1 116 REWVTAIEAVNSTGWALPSYVIFKATTYyQQGWF---ETLPQDRRLDISKNGWTTDEIGIRWLqKHFIPHTTsrTKSRYRMLILDGHGSHLTAQFdRIC 211
                 7899********************9876266777...777888889999********************99988999******************999* PP

       DDE_1  96 elqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                 +++ni +v++P++s++llqPld++++s lK++Y r + q +  + n+++k        d+l     A++ a + e+i+++f
  EEA18548.1 212 AENNIITVCMPPHSSHLLQPLDVSCFSVLKRQYGRLVEQRVRLGFNHIDK-------YDFLTAFPEARTmAYKTENIQNGF 285
                 *************************************************9.......999999999999999999999988 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.9   0.0   2.5e-09   1.5e-05       3      52 ..      69     112 ..      67     119 .. 0.89

  Alignments for each domain:
  == domain 1  score: 24.9 bits;  conditional E-value: 2.5e-09
                  HHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHH CS
  HTH_Tnp_Tc5   3 elEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgW 52 
                   +E++Ll+W+ +l++rg p++ +l++++A  + +      ++d ++S++W
   EEA18548.1  69 FEEDSLLKWVLDLDKRGLPPRPSLVQDMADLFSQ------HRDEHVSEKW 112
                  589****************************944......4788888888 PP

>> DDE_3  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0      0.27   1.6e+03      57     102 ..      67     110 ..      38     135 .. 0.53
   2 !   19.8   0.0   8.9e-08   0.00053      59     119 ..     166     228 ..     153     249 .. 0.82

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.27
       DDE_3  57 etlnaedfaeflerlletalqakkivlilDnasiHkseslrelvee 102
                  ++ +++  +++ +l ++ l + +  l+ D a  +   +  e+v+e
  EEA18548.1  67 TQFEEDSLLKWVLDLDKRGLPP-RPSLVQDMADLFSQ-HRDEHVSE 110
                 5555555555666666666665.66666666653322.22222222 PP

  == domain 2  score: 19.8 bits;  conditional E-value: 8.9e-08
       DDE_3  59 lnaedfaeflerlletalqak....kivlilDnasiHkseslrelveeeadrlellylPpySPel 119
                  + e+ +++l++   +++ ++      +lilD+++ H  +++ ++ +e   ++ ++ +Pp+S++l
  EEA18548.1 166 TTDEIGIRWLQKHFIPHTTSRtksrYRMLILDGHGSHLTAQFDRICAE--NNIITVCMPPHSSHL 228
                 567778889999888888887888899*********************..*************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (365 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       446  (0.0248759); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2574.13
//
Query:       EEA18549.1  [L=302]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.6e-27   94.8   0.6    7.3e-27   94.4   0.6    1.1  1  NmrA            NmrA-like family
    2.2e-17   63.5   0.1    1.6e-16   60.7   0.0    2.0  2  NAD_binding_10  NAD(P)H-binding
    0.00043   20.7   0.3    0.00079   19.9   0.1    1.6  2  Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domai
  ------ inclusion threshold ------
       0.02   14.3   0.1       0.13   11.7   0.1    2.0  2  Epimerase       NAD dependent epimerase/dehydratase family
        0.1   12.7   0.7        0.2   11.8   0.1    1.9  2  DapB_N          Dihydrodipicolinate reductase, N-terminus


Domain annotation for each model (and alignments):
>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.4   0.6     2e-30   7.3e-27       1     232 [.       8     232 ..       8     233 .. 0.86

  Alignments for each domain:
  == domain 1  score: 94.4 bits;  conditional E-value: 2e-30
                 EEESSTTSHHHHHHHHHHHH.HT-EEEEEES-S-SHHHHHHHHSTTEEEES-TT-HHHHHHHHTT-SEEEE---GGS-HHHHHHHHHHHHHHHS-SEEE CS
        NmrA   1 IlviGaTGrqGksvvrallk.aghkvralvRdtkselakslkeaGvelvkgdlddkeslvealkgvdvvfsvtgfyskeiedgkklvdAakeaGvkhfi 98 
                 +++iGa+G+ G+ + +a++  ++++v +l+R ++s +      aGv++ k d  +++ lv+a+kg +vv+sv+g       d+kk +dAa  aGvk+fi
  EEA18549.1   8 VAIIGASGNVGSIILDAFVGaSQFNVTVLTRSSSSATF----PAGVTVRKSDFSEQD-LVSAFKGQNVVISVVG--LGAFTDQKKFIDAAISAGVKRFI 99 
                 79***************99879**********999887....57***99*9998765.899*************..999******************** PP

                 EEE---GG.GT.SSS---TTTHHHHHHHHHHHHC...TS-EEEEEE-EEGGG-BSSS-SS-BEEE-TTS.-EEEEESS-TTS-EE-HHHHHHHHHHHHH CS
        NmrA  99 ySslgddndrsnaeepavphfdsKaeieeyvral...gipytfvyagffmenflsllaqlkvgdtappedkvtllgpgnpkavlldaeeDiGafvikil 194
                 +S++ ++   s a+   +p+f++K e+ +y++     g+  t + + +f    l++      g   p + ++ +   gn+  + ++++e   ++vi++l
  EEA18549.1 100 PSEFSANT-LSPAVVQLLPVFAQKKEVLDYLKTKeasGLTWTAIWTALFFDQCLTTGFL---GFDLPTR-TASIWDGGNS-VFTVTNVEQLQRAVIATL 192
                 ****9998.8889999***************877677*****99998887777774433...3444444.6666666663.333379************ PP

                 HHHHHHTTEEEEE-SEEE-HHHHHHHHHHHHTS-..EEEE CS
        NmrA 195 kdprklkgkriklagntlsgneivelfekkigkt..vkYt 232
                 ++p+++ +k + +a+ + s ne+++++ek++  +  v+Yt
  EEA18549.1 193 ERPAETANKNLYIASVETSQNELLAALEKATASKwtVTYT 232
                 *****************************98664447776 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.7   0.0   4.5e-20   1.6e-16       1     149 [.      12     150 ..      12     168 .. 0.85
   2 ?    0.6   0.1      0.12   4.4e+02      38      99 ..     200     260 ..     174     286 .. 0.56

  Alignments for each domain:
  == domain 1  score: 60.7 bits;  conditional E-value: 4.5e-20
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHHCTTTCEEEE--TT-CCHHHHHHTT-SEEEES---TCCHHHHHHHHHHHHHHCT--EEEE CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpeklaeleaeeglevvegdvtdvedlaealkgadaVvsalggggkdeegaknivdaakeagvkRfvl 95 
                     GA+G+vG+ +++  + +++++vt+l+R++++++ ++  +g++v + d++ ++dl +a+kg+++V+s +g g+   +  k+ +daa  agvkRf+ 
      EEA18549.1  12 GASGNVGSIILDAFVGASQFNVTVLTRSSSSAT-FP--AGVTVRKSDFS-EQDLVSAFKGQNVVISVVGLGAF--TDQKKFIDAAISAGVKRFIP 100
                     9*******************************9.76..8*********8.899***************98875..568****************9 PP

                     EEETTTTSGCGCHHHHHHHHCCHHHHHHHHHHHHHHHH...SSSEEEEEEE-CEE-S CS
  NAD_binding_10  96 vsaigvgdevpgefgewnkellkaylaakraaeellra...sgldwTivrpggLtde 149
                        + ++      +++ +   l +++a k++  ++l++   sgl+wT +  + + d+
      EEA18549.1 101 SE-FSANT-----LSPAV-VQLLPVFAQKKEVLDYLKTkeaSGLTWTAIWTALFFDQ 150
                     55.55553.....22222.23568999999*9999977667******9988887776 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.12
                     TTTCEEEE--TT-CCHHHHHHTT-SEEEES---TCCHHHHHHHHHHHHHHCT--EEEEEEET CS
  NAD_binding_10  38 eeglevvegdvtdvedlaealkgadaVvsalggggkdeegaknivdaakeagvkRfvlvsai 99 
                     +++l + +++  ++++l +al+ a a  +++  + +de++ + i++  k   +  fvlv a 
      EEA18549.1 200 NKNLYIASVET-SQNELLAALEKATASKWTVTYTTTDEQVSEGIARLGKGDMTGAFVLVKAT 260
                     34444444433.35566666666666655555555555555555555555555555555555 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   0.1   2.2e-07   0.00079       1      75 [.       7      78 ..       7     120 .. 0.73
   2 ?   -3.0   0.0       2.7   9.7e+03      38      50 ..     213     225 ..     187     243 .. 0.49

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 2.2e-07
                    EEEEETTTSHHHHHHHHHHHCTSSEEEEEEEESTTTTTSBHHHHSGGGTTTECEBEEE.GGGGGCTT-SEEEE-SC CS
  Semialdhyde_dh  1 kvaivGatGyvGqellrlLeehpevelvvllsssrsaGkklaeavkaleegkdlkved.vdeeelkevdivflalp 75
                    +vai+Ga+G+vG+ +l       +++++vl+ ss+sa  +    v+    ++d++ +d v++ + ++v i +  l+
      EEA18549.1  7 NVAIIGASGNVGSIILDAFVGASQFNVTVLTRSSSSATFPAGVTVR----KSDFSEQDlVSAFKGQNVVISVVGLG 78
                    7*******************************99987666666655....55555555333444444444444444 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 2.7
                     TSBHHHHSGGGTT CS
  Semialdhyde_dh  38 Gkklaeavkalee 50 
                      + la++ ka+++
      EEA18549.1 213 NELLAALEKATAS 225
                     3333333332222 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.1   3.6e-05      0.13       2      71 ..       9      77 ..       8      95 .. 0.79
   2 ?    0.3   0.0      0.11     4e+02     202     237 ..     168     203 ..     156     236 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 3.6e-05
                EEETTTSHHHHHHHHHHHHCT.SEEEEEES-STTTTCHHCHHCEEEE--TT-HHHHHHHHHHHT-SEEEE- CS
   Epimerase  2 lVtGatGfiGsalvkallekg.yevigldrlssasntarledlelveldltdrsalerlfkeeqpdavihl 71
                 ++Ga+G +Gs +++a+  +   +v++l+r ss+  + +    ++ + d+ +++ + ++  ++ +  v+ l
  EEA18549.1  9 AIIGASGNVGSIILDAFVGASqFNVTVLTRSSSSATFPAGV--TVRKSDFSEQDLVSAFKGQNVVISVVGL 77
                69****************999566*******8888876554..8889999999988887666555555555 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.11
                 EETTST-EEEEEEHHHHHHHHHHHHHHHTT-STTEE CS
   Epimerase 202 llgdgtalRdflyveDvaeaillvlehvdagdkgei 237
                 +++ g+++     ve + +a+++ le++++ ++++ 
  EEA18549.1 168 IWDGGNSVFTVTNVEQLQRAVIATLERPAETANKNL 203
                 677777777888888888888888888777665544 PP

>> DapB_N  Dihydrodipicolinate reductase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.1   5.6e-05       0.2       2      38 ..       7      43 ..       6      98 .. 0.73
   2 ?   -2.6   0.0       1.6   5.6e+03      24      31 ..     211     218 ..     176     241 .. 0.59

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 5.6e-05
                EEEEETTTSHHHHHHHHHHHHSTTEEEEEEEETTCST CS
      DapB_N  2 kvavvGasGrmGkevvkaveeaedlelvaavdrkese 38
                +va++GasG +G+ +++a   a++++++    +++s+
  EEA18549.1  7 NVAIIGASGNVGSIILDAFVGASQFNVTVLTRSSSSA 43
                69************************99887777632 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.6
                 TTEEEEEE CS
      DapB_N  24 edlelvaa 31 
                 ++ el aa
  EEA18549.1 211 SQNELLAA 218
                 22233333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (302 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       630  (0.0351386); expected 358.6 (0.02)
Passed bias filter:                      484  (0.0269954); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.55u 0.31s 00:00:00.86 Elapsed: 00:00:00.50
# Mc/sec: 1830.59
//
Query:       EEA18550.1  [L=332]
Description: hypothetical protein PMAA_008290 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        1.5    8.9   3.4       0.79    9.7   0.6    2.0  3  DUF4192   Domain of unknown function (DUF4192)


Domain annotation for each model (and alignments):
>> DUF4192  Domain of unknown function (DUF4192)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0     0.094   1.7e+03     144     191 ..      32      74 ..      28     102 .. 0.65
   2 ?    9.7   0.6   4.4e-05      0.79     173     252 ..     136     215 ..      89     226 .. 0.75
   3 ?   -3.7   0.0      0.52   9.3e+03     144     179 ..     276     310 ..     270     315 .. 0.62

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.094
     DUF4192 144 vegsReelearlapvega.aaraaqrraaeraaaaleralarprdaerr 191
                 ++ s +++ea+++pv+++ +        +  +a+ +er ++r++ + r+
  EEA18550.1  32 PRQSSTPIEALFTPVTPNcE------TSQTPIAPSIERSQLREASQLRN 74 
                 67788889999999977633......23345556666666655555554 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 4.4e-05
     DUF4192 173 raaaaleralarprdaerrsdpaevrraaleavraalarvaagaglsdaeeaarlavaLtdvrvRDaalalalgeeaaaa 252
                 +a+ ++++a +++ +  r+ +++   + a++++ + l+++ + ++ ++a++++++    ++v  RD +l+ ++++ ++ a
  EEA18550.1 136 EARVRAREAYTQKYETGRETEASTPLDVAIDEWIEFLQEYSEEEKEESAQKTQDILFQQQQVLYRDGLLETMEKAAKRRA 215
                 22222222222222333337789999*******************99999**********************96555544 PP

  == domain 3  score: -3.7 bits;  conditional E-value: 0.52
     DUF4192 144 vegsReelearlapvegaaaraaqrraaeraaaale 179
                 +  +R+ + ++++p    ++++a +++++ ++++++
  EEA18550.1 276 LKQDRRLIKSLITPSSN-KDHDALAQQVKNISKRVD 310
                 55677777777777544.445555665666666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (332 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1907  (0.106364); expected 358.6 (0.02)
Passed bias filter:                      597  (0.033298); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.48
# Mc/sec: 2095.33
//
Query:       EEA18551.1  [L=895]
Description: hypothetical protein PMAA_008300 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.4e-57  194.5   0.1    8.3e-53  180.0   0.0    2.2  2  COesterase     Carboxylesterase family
    1.8e-11   43.6   0.1    2.7e-11   43.0   0.1    1.3  1  Fungal_trans   Fungal specific transcription factor domain
    4.4e-06   26.7   8.5    1.7e-05   24.9   8.5    2.0  1  Zn_clus        Fungal Zn(2)-Cys(6) binuclear cluster domain
    5.2e-06   26.5   0.2    2.5e-05   24.3   0.1    2.2  2  Abhydrolase_3  alpha/beta hydrolase fold
  ------ inclusion threshold ------
      0.023   14.7   0.8      0.064   13.2   0.8    1.8  1  Tnp_22_trimer  L1 transposable element trimerization domain
       0.04   13.4   0.0      0.079   12.4   0.0    1.4  1  Peptidase_S9   Prolyl oligopeptidase family
       0.12   12.6   0.4       0.49   10.6   0.4    2.1  1  XhlA           Haemolysin XhlA


Domain annotation for each model (and alignments):
>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  180.0   0.0   3.2e-56   8.3e-53     101     337 ..       3     242 ..       1     303 [. 0.80
   2 !   12.5   0.5   1.9e-05     0.049     457     512 .]     305     363 ..     258     363 .. 0.84

  Alignments for each domain:
  == domain 1  score: 180.0 bits;  conditional E-value: 3.2e-56
                 TTSSEEEEEEE--STTTS-BGCGS-THHHHHHH..TSEEEEE----HHHHH-B-SS..TTSBS-HHHHHHHHHHHHHHHHGGGGTEEEEEEEEEEETHH CS
  COesterase 101 akkklPVlVwihGggfqtgsaseydgsaLaaeg..nvivVtinYRlGvlGFlstgd..eeapGNvGllDqvlALrWVkenIasFGGdpervtlfGesAG 195
                 +++klPV++w+ Gg++  + + +y+++ L++    n ivVt+nYR+G++GFl+ +d  ++ + N+Gl Dq+ A+ WV+++I++FGGdpervtlfG+sAG
  EEA18551.1   3 RSSKLPVMIWFQGGAYILNLNADYNATGLIQASsdNFIVVTFNYRVGLFGFLASQDvkNDGDLNAGLSDQRKAIIWVHNHISAFGGDPERVTLFGTSAG 101
                 57899************************998888*******************995566666************************************ PP

                 HHHHHHHHHS....GGGTTSBSEEEEES--TTSTTTSBSH.HHHHHHHHHHHTTS-CSSHHHHHHHHHCS-HHHHHHCCGG..SSSSSSTTC-SSS-B- CS
  COesterase 196 aasvslllls....plsrglfkraIlqSGsalspwaiqkk.arkrakklakkvgckassskelveclrsksaeelldaqek..aleasssklvsfaPvv 287
                 a  v l++l     ++s+ lf  aI+     + p    ++    + +++ ++++c      + +eclr  ++++ll+a+ +  +  +++s+l+ f+P v
  EEA18551.1 102 AGGVLLHTLAyggeNTSKPLFSAAISADP--FVPEIFPYQrLEFQYQEILNATNC------SSLECLRHLPTDSLLAANINrpFPRQTTSPLFYFSPCV 192
                 *********8555467778******8775..555555555488899*********......6699**************9999889999********** PP

                 -SSSSSS-HHHHHHCGC..CSEEEEEEETTTTHHHHCCHSTTTSSSSHHHHH CS
  COesterase 288 dgdflpekPeellkseg..kvplliGvnkdegllflaylldkeksvkkkeek 337
                 dg f+p+ P++ll+      vpll G+++deg++f+a+  ++   v++ +e 
  EEA18551.1 193 DGIFFPDLPSKLLADGRfqRVPLLQGTVTDEGSIFAATANNT--DVDQFDEF 242
                 ***************66*******************954443..23222222 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 1.9e-05
                 HHHHHHHHHHHHHSSTTS...TTSS----B.TTTBEEEEESSSSSEEEESTTHHHHHHH CS
  COesterase 457 rkmmtywtnFaktgnPnk...eeeekWpkytkeeekylkinlkpkrvkkklkeeevafw 512
                   +  ywt+Fa+  +Pn    e++++W+   + ++  ++ n +++++ +  + e+++fw
  EEA18551.1 305 PVVQAYWTSFARAHDPNVwrlEGSPEWKTWGSGQRLKIQTNSTAMEMVDRQQIENCEFW 363
                 56789*************************77777777777777788888999999998 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.0   0.1   1.1e-14   2.7e-11       2     169 ..     560     722 ..     559     793 .. 0.84

  Alignments for each domain:
  == domain 1  score: 43.0 bits;  conditional E-value: 1.1e-14
  Fungal_trans   2 drffsnfhpqfpilhkpsflpkt..ssenssksayaspllllailalGalfsesetkesnssltses.....qefiafplraeilihedfsspsssl 91 
                   +++ + + p++ ++h ps  +    + ++ ++++ +  +l +ai   + l+++  + +s+ ++++++     +++i ++ +   ++       ++++
    EEA18551.1 560 QTYLERVDPLLKLIHVPSTQKILmqACKEIKIANPNTVCLTYAIAYAAILSMSPMECISDLQHSKSVlltrcRNKIDECFSEINVL------DTRNM 650
                   57888888999999998888888554555555666666666999999999999999999999888778888888887777776666......8888* PP

  Fungal_trans  92 wilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialk 169
                   ++lq+L+l+  +       + +  ++g+a+ +a +++ +r+  ++        +++eae+rrRlww +  lD+++a +
    EEA18551.1 651 NVLQALVLYLKCGRLDPQGPNVHSLIGMAIGIAIKMHINRDGDQSD------IPPFEAEMRRRLWWHILTLDVLTAQD 722
                   *********************************************9......9********************99865 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.9   8.5   6.5e-09   1.7e-05       2      34 ..     427     457 ..     426     460 .. 0.93

  Alignments for each domain:
  == domain 1  score: 24.9 bits;  conditional E-value: 6.5e-09
                 S-HHHHHCT---STSSSS-HHHHHCTHHHCCCC CS
     Zn_clus   2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfys 34 
                 +C +Cr++K+ C++ +P Cs C+k   +C  y+
  EEA18551.1 427 PCLECRRRKIGCNRSHP-CSYCVKTKIQCI-YP 457
                 7****************.***********9.76 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.3   0.1   9.6e-09   2.5e-05       1     104 [.      10     126 ..      10     157 .. 0.75
   2 ?   -3.7   0.0       3.4   8.6e+03     127     153 ..     545     568 ..     511     589 .. 0.63

  Alignments for each domain:
  == domain 1  score: 24.3 bits;  conditional E-value: 9.6e-09
                    EEEE--STTTS--TTTTHHHHHHHHHHHTSEEEEEE--......-TTTS.....-TTHHHHHHHHHHHHHHHTHHHHTETTCEEEEEEETHH..HH CS
  Abhydrolase_3   1 lvyfHGGGfvlgsldthdalcrelakelgavvvsvdYr......lAPeh.....pfPaavedalaalrwlaeqawelgadpsrivlaGdSaG..Gn 83 
                    +++f GG+++l   + ++a+    a+  + +vv  +Yr      lA +       + a + d  +a+ w++++ +++g dp+r++l+G+SaG  G 
     EEA18551.1  10 MIWFQGGAYILNLNADYNATGLIQASSDNFIVVTFNYRvglfgfLASQDvkndgDLNAGLSDQRKAIIWVHNHISAFGGDPERVTLFGTSAGagGV 105
                    6789999999888888877777788888999999999966655556664333336899***************99***************862256 PP

                    HHHHHHHHHHHTT---EEEEE CS
  Abhydrolase_3  84 laaavalrardegepkvagqv 104
                    l + +a    ++++p  ++ +
     EEA18551.1 106 LLHTLAYGGENTSKPLFSAAI 126
                    666666555555555555555 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 3.4
                    TTSSSSCHHHHHHHHHHHSSGGGGGST CS
  Abhydrolase_3 127 adgplltraaldlfwrlylpeadrddp 153
                    +++ ++++ +l  +w+ yl+   r dp
     EEA18551.1 545 ESNEIFSPMTLVSMWQTYLE---RVDP 568
                    34456666677778888885...3334 PP

>> Tnp_22_trimer  L1 transposable element trimerization domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.8   2.5e-05     0.064       1      23 [.     477     499 ..     477     504 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 2.5e-05
                    HHHHHHHHHHHHHHHHHHHHHHH CS
  Tnp_22_trimer   1 RidelEERvSaaEDeieeidrev 23 
                    R+d  EER S  E  ++e+++ v
     EEA18551.1 477 RVDGVEERLSVLERHMNEMKQLV 499
                    99******************876 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   3.1e-05     0.079      12     117 ..      36     147 ..      26     164 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 3.1e-05
                   CCT-EEEEE--TTSST...THCHHHHTTSGGGGHHHHHHHHHHHHHHHHTTS--GGGEEEEEETHH..HHHHHHHH....HH-GGG-SEEEEESE-- CS
  Peptidase_S9  12 drGyvvvvanirGsgg...yGeafhdagkrklgqnefdDfiaaaealakegyvdserlaitGgSyG..Gyltgaal....nqrpdlFkaavaevpvv 99 
                   + +++vv  n+r +      +++ +++g+ + g  + +  i ++   ++ +  d+er+ ++G+S+G  G+l  +++    n  + lF+aa++++p+v
    EEA18551.1  36 SDNFIVVTFNYRVGLFgflASQDVKNDGDLNAGLSDQRKAIIWVHNHISAFGGDPERVTLFGTSAGagGVLLHTLAyggeNTSKPLFSAAISADPFV 132
                   6789999999997653222588999999999999999999999999999***************8532777665553333356789**********9 PP

                   -CCCHHCSTTSTHHHCCC CS
  Peptidase_S9 100 dvlrydsdtdllteeyme 117
                     +  ++    l+ +y+e
    EEA18551.1 133 PEIFPYQR---LEFQYQE 147
                   77777766...4445555 PP

>> XhlA  Haemolysin XhlA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.4   0.00019      0.49       4      34 ..     469     499 ..     468     504 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00019
        XhlA   4 erlerietkldnleervdkleekaaeaeeki 34 
                 +++e +e+++d  eer++ le++++e+++ +
  EEA18551.1 469 DKIEYVERRVDGVEERLSVLERHMNEMKQLV 499
                 69999**********************9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (895 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       530  (0.029561); expected 358.6 (0.02)
Passed bias filter:                      413  (0.0230353); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.72u 0.30s 00:00:01.02 Elapsed: 00:00:00.46
# Mc/sec: 5821.07
//
Query:       EEA18552.1  [L=476]
Description: MFS monocarboxylate transporter (Mct), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.5e-27   94.6  57.4    1.9e-18   66.6  25.2    2.4  2  MFS_1       Major Facilitator Superfamily
     0.0016   17.4  23.1      0.035   12.9  23.0    2.1  1  MFS_1_like  MFS_1 like family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.6  25.2   2.1e-22   1.9e-18      10     225 ..      97     304 ..      82     312 .. 0.73
   2 !   32.3  30.2   5.3e-12   4.7e-08       8     178 ..     293     472 ..     287     476 .] 0.79

  Alignments for each domain:
  == domain 1  score: 66.6 bits;  conditional E-value: 2.1e-22
       MFS_1  10 larsilgpalplalaedlg..ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll.fasslw.lllvlrvlqGlgagalfp 104
                 l++ + + ++ +++ ++l   +s+s+i+++ ++  ++++v+s+++G l drfG+r v+l g +l ++g l+++ +++s++ lll   v ++lg +a+f 
  EEA18552.1  97 LGWLNSIGIFQSYYETTLLrqYSASAISWIPSFEIFFTFVTSPVIGQLYDRFGPRFVILGGSFLHVFG-LMMAsLSTSYYqLLLSQGVCSALGICAIFQ 194
                 33333344443333222224499*********************************************.6666476778867777788888888***** PP

       MFS_1 105 agaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeeekgtgpaplvpawkal 203
                  +++ i  wf + +rg a+g++s+g+slG ++ p+  + l+  +g+++++ i a++ l+++v+  + l+++ + ++ + +++ +   + + l p +k++
  EEA18552.1 195 PCMSCIPSWFQR-RRGIAYGIVSSGTSLGGVIFPIMVSRLIKIVGYSWSMRISAFLILFLLVI--VNLTVKTRLPPSPQTQKMS---KTTLLQP-LKEI 286
                 ***********9.***********************************************775..4444444444444444441...2333333.5555 PP

       MFS_1 204 lkdpvlwillialllfffgfsg 225
                    +    +++++++ +fg++ 
  EEA18552.1 287 PMIN----VVLGFFFLTFGVFV 304
                 5555....34444444333333 PP

  == domain 2  score: 32.3 bits;  conditional E-value: 5.3e-12
       MFS_1   8 salarsilgpalpl.al...aedlgispseigllltlyalgaavaslplGrlsdrfGrrr.vlllglllfalglllllf.asslwlllvlrvlqGlgag 100
                  ++ + ++g+++p+ +l   a+  g+s   ++ l+ +  ++++++ l++G+lsdr+G    ++++++l+ +++ l+l++ a++  +++++ +l G+++g
  EEA18552.1 293 LGFFFLTFGVFVPInYLvvqATKVGMSSNLAQYLAPILNAASLFGRLLAGVLSDRIGTYNvLMIACYLAGIFC-LALWIrAANTAAVMAFTILFGMTSG 390
                 34444444444444444444899*************************************6666677766666.66663347877************** PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllgglla..sslgWravfyilaivslla..fvlfllllpeeppe 178
                 a+++++aal+++++p +  g  +gll    +++ + + +++g+++  + ++++++ ++ ++ +l++  f+l++  + + p+ 
  EEA18552.1 391 AYIALSAALVVRISPIRGIGYRTGLLFFIGAFSGLTASPIAGAILqrEDGSYTGMQIFSGATLLVGssFILVVRIYKTGPVL 472
                 ****************************999999888777777774666778888777777777776677777777666655 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.9  23.0     4e-06     0.035      29     362 ..     116     420 ..     100     443 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 4e-06
  MFS_1_like  29 kglkaseigiitlilpltsilsppiwgvlaDrfgkrkkvvilslllsavlflsllfippskerqeesklevsvaqdvdaektfwilfllvvlasfflaa 127
                 ++++as i  i +   +++++ +p++g l Drfg r  v++ +++l +  +   ++ +                     ++++  l+l   + s++  +
  EEA18552.1 116 RQYSASAISWIPSFEIFFTFVTSPVIGQLYDRFGPRF-VILGGSFLHVFGL---MMAS--------------------LSTSYYQLLLSQGVCSALGIC 190
                 5789999***************************985.4445555544433...3444....................678888888888888888877 PP

  MFS_1_like 128 ilvlldaatlkel.gedrkd.yGrqrlfGsvGyaifafitGilidhysvnllp.ysallyvlaallvisllvvlilnetekesklkvtkslqvllnilk 223
                 ++++    ++    + +r+  yG +    s+G +if ++++ li  +  ++   +s ++++l +l+++ l+v   l+   + +k+  t     ll+ lk
  EEA18552.1 191 AIFQPCMSCIPSWfQRRRGIaYGIVSSGTSLGGVIFPIMVSRLIKIVGYSWSMrIS-AFLILFLLVIVNLTVKTRLPPSPQTQKMSKT----TLLQPLK 284
                 777776677766645555557*************************9998866554.4555555556666665666666655555555....4566677 PP

  MFS_1_like 224 npeviifllvalilgmswgiienFlflYLkelgasntllGslvalgvvaeiplfffaeklleklGhvklliiallayilrfllyaii..enawlvlpie 320
                 +  +i ++l  ++l + + +  n+l +   ++g s+ l+  l ++  +a++   ++a  l +++G  ++l+ia  +  + f+l  +i   n+  v+ + 
  EEA18552.1 285 EIPMINVVLGFFFLTFGVFVPINYLVVQATKVGMSSNLAQYLAPILNAASLFGRLLAGVLSDRIGTYNVLMIACYLAGI-FCLALWIraANTAAVMAFT 382
                 77777777777777777777789***********************************************999877665.555555567999******* PP

  MFS_1_like 321 vLhgisfgllwaaaveyvskiapksleatgqgllsglyfglG 362
                 +L g++ g++ a  +  v +i p + ++   gll  +    G
  EEA18552.1 383 ILFGMTSGAYIALSAALVVRISPIRGIGYRTGLLFFI----G 420
                 *******************9**999888888876443....3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (476 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       794  (0.0442858); expected 358.6 (0.02)
Passed bias filter:                      333  (0.0185733); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.33s 00:00:00.93 Elapsed: 00:00:00.47
# Mc/sec: 3050.64
//
Query:       EEA18553.1  [L=1032]
Description: NRPS-like enzyme, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      2e-29  102.5   0.0    3.2e-29  101.8   0.0    1.2  1  AMP-binding    AMP-binding enzyme
      3e-27   95.4   0.0    4.5e-27   94.8   0.0    1.3  1  NAD_binding_4  Male sterility protein
    4.1e-12   46.1   0.0    6.7e-12   45.4   0.0    1.3  1  Epimerase      NAD dependent epimerase/dehydratase family
     0.0012   19.1   0.0      0.003   17.9   0.0    1.7  1  PP-binding     Phosphopantetheine attachment site
  ------ inclusion threshold ------
      0.019   14.0   0.0      0.033   13.2   0.0    1.3  1  3Beta_HSD      3-beta hydroxysteroid dehydrogenase/isomerase 
      0.025   14.5   0.0      0.062   13.2   0.0    1.7  1  KR             KR domain
      0.051   13.0   0.0       0.13   11.6   0.0    1.6  1  GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
       0.46   10.6   1.4        5.7    7.1   0.0    2.7  3  VirE1          Single-strand DNA-binding protein


Domain annotation for each model (and alignments):
>> AMP-binding  AMP-binding enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.8   0.0   1.4e-32   3.2e-29      18     365 ..      37     367 ..      16     373 .. 0.80

  Alignments for each domain:
  == domain 1  score: 101.8 bits;  conditional E-value: 1.4e-32
                  CSTEEEEHHHHHHHHHHHHHHHHHTTSST...T-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHH..TESEEEETCTCCC.HHH CS
  AMP-binding  18 gegqtlTYreldervnrlAagLrslGvkk...gdrVaillpnspewvvallailkaGavvvplnptltaeelayileds..eakvliatvdsel.lek 109
                   +++ +T + l++ v+  A+ L ++G ++   + +++i++p+ ++++v ++++ ++G +v  l+p+l++ +++ +l++   + ++l+  +  +    k
   EEA18553.1  37 TDYEPVTGATLNHFVDGTAKCLIEKGFQPvreEVVIGICSPTDLDYIVNIFGLIRLGYTVFQLSPRLPPSAVKELLAKIqnGRRALL--YTPAHtSFK 132
                  578999*****************999865221556*****************************************98622568888..433332333 PP

                  HHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHHHHCSCCTTT-EEEE CS
  AMP-binding 110 lleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkletrfklkeddvvls 207
                       ++l + +l  ++++de ++++++++ e   e       + e + +  ++i+ +SG+TG PK + + h+ l+a+   +         +d + + 
   EEA18553.1 133 ----LDALSDLELFPLVQRDEYDNSRHSETPEFLLE----G-VDYEKEHSRRCLILHSSGSTGLPKPIDYNHQKLLAAGVYA---------QDATAFI 212
                  ....34456677888889888777655555554332....2.3335677889********************9999985553.........2446688 PP

                  SS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEEEESS-EBHHHHHHHHH CS
  AMP-binding 208 ilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvllggeplspellrffra 305
                   +p++h++g+ ++ + a+++ +t++ +++  + + +++ +++++ ++ ++++vP +l+ l+e+++          +  r+v +gg++l+ el + + +
   EEA18553.1 213 SMPFSHALGM-MSYMQAIHKRGTIYAMSGYVPQTHDTVTAAVKAANPEIMWTVPYILKLLAEKPDGI-----DAIKNCRFVSSGGSKLPDELGDMLTE 304
                  9********8.********************97778999***********************65443.....25667***999*************** PP

                  HHTCEEEEEEEEGGGSSECEE...CHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBEE.TTSEE CS
  AMP-binding 306 lfgeevlegYGlTEttgvvtv...lpleedkkklgsvGkplpgvevkivDeetgepvp.dgeeG 365
                   + + +   +G TEt+ +++    +++++ +++l     ++p +  k vD ++ e v  dg++G
   EEA18553.1 305 AGVH-IGMQFGSTETGLILSSayrDREDKAWNYLRPPAHVVPYIMFKPVDHDKYECVVlDGHKG 367
                  *876.9*************554576667777777767777777777777877666554466666 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.8   0.0     2e-30   4.5e-27       1     256 [.     662     905 ..     662     906 .. 0.82

  Alignments for each domain:
  == domain 1  score: 94.8 bits;  conditional E-value: 2e-30
                    EE-TTSHHHHHHHHHHHHHS-.T.EEEEEE-..SSSHHHHHHHHHHHT-SS-HHHHHHHHHTTTEEEEE--TTSGGGG--HHHHHHH.HHH--EEE CS
  NAD_binding_4   1 lTGaTGFLGkvLlekLLrttpev.kiyllvR..aksgesaeeRleeelekkelfsallkelaerikvveGDlseprlGLseedlqel.aeevdvii 92 
                    lTG+TGFLG+++l+ L+ +++ v k+y+ +R  ++ +++++ Rle++l+ k++   l     ++++++ +D++e+++GL+ +++ +     v+++i
     EEA18553.1 662 LTGVTGFLGAHILAALVASSS-VsKVYAFMRpnSEAKQTPLVRLERSLQAKGFSISL-----NKVIPLYADITEENFGLKTAEMYKTmKLLVTHVI 751
                    8******************98.66*******43344668999**9999999987555.....8****************987665552778***** PP

                    E--SS-S.STTSSEEHHHHHHHHHHHHHHHTSSS--.-EEEEEE.GGGTTS-TTT--SSS-H......HHH--EEEETTTCCCHHHHHHHHHHHHH CS
  NAD_binding_4  93 hsaAtvnfdepykellrvNveGtrevlelakklkklkvllhvST.ayvngeregeveekvyeegekeekldederaklkglpntYeqsKalaEklv 187
                    h+a  vnf  ++  ++++ ++G +++l +  +  ++  +l++S+ ++++ +  ++             +++ + ++ +   + +Y+qsK ++E++v
     EEA18553.1 752 HCAWAVNFAIQLT-AFEPQLLGLHNLLAFGLESDRNARVLFCSSiGTAQATPGTA------------TIASAMLPSFDSCSSMGYSQSKLVGEHIV 834
                    *********9995.7899******************9******965555555543............3466777777777777************* PP

                    HHHHHHH---EEEEEE-EEE--SSST..---TTSHHHHHHHHHHH..H-EEES-SB---TT--EEEHHHHHHH CS
  NAD_binding_4 188 rearrrsglpvvivRpsiitgesktG..wingsdlgirgllglia..kgvlpeilgdkeavldlvpvDyvana 256
                    ++a ++ g +++++R++ i+     G    n s+ ++ ++ ++ +  +g+lp il + + ++d++ +D++a++
     EEA18553.1 835 ESATKN-GANATVLRIGQIIPGRRRGskLWNPSEATPLMIRSASKdsTGALP-ILDTGRDTCDWIEADTLADT 905
                    ****77.*************96666644456666577777777765567777.77777788899988888876 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.4   0.0     3e-15   6.7e-12       1     226 [.     660     910 ..     660     925 .. 0.79

  Alignments for each domain:
  == domain 1  score: 45.4 bits;  conditional E-value: 3e-15
                 EEEETTTSHHHHHHHHHHHHCT..SEEEEEES-STTTTCHHCHHC................EEEE--TT-HH......HHHHHHHHHT-SEEEE--S-- CS
   Epimerase   1 ilVtGatGfiGsalvkallekg..yevigldrlssasntarledl................elveldltdrs......alerlfkeeqpdavihlAavg 75 
                 +++tG+tGf+G++++ al +     +v ++ r +s+ ++  l +l                   ++d+t+++      ++ + +k   +++vih+    
  EEA18553.1 660 VILTGVTGFLGAHILAALVASSsvSKVYAFMRPNSEAKQTPLVRLerslqakgfsislnkvIPLYADITEENfglktaEMYKTMK-LLVTHVIHC---- 753
                 579****************99996669999999888887777777999***********99888999999997774333333333.267888888.... PP

                 -HHHHHHSHHHHHHHHTHHHHHHHHHHHHHTCT.EEEEEEEGGGGTSCSSSSBSTCSTTS--..--SSHHHHHHHHHHHHHHHHHHHHT-EEEEEEESE CS
   Epimerase  76 gvaassedpadfieknlqgtlnlleaarkagvk.rllflsSsevYGkdaeqpkeettltgpl..kpnspYaaaKlageklveayaaqyglnaiilrlfn 171
                  +a+++  +   +e  l g  nll    +++ + r+lf+sS  +  + + + +  ++   ++   ++  Y+ +Kl ge++ve++++ +g na++lr+  
  EEA18553.1 754 AWAVNFAIQLTAFEPQLLGLHNLLAFGLESDRNaRVLFCSSIGTAQATPGTATIASAMLPSFdsCSSMGYSQSKLVGEHIVESATK-NGANATVLRIGQ 851
                 899************************9996666*******4444433332222222233345678889*************9755.569********* PP

                 EESTT.S-TTS..TTSHHHHHHHHHHTTS.SSEEEETTST-EEEEEEHHHHHHHHHHHH CS
   Epimerase 172 lyGpr.ngege..vsrvipalirkilegk.qevtllgdgtalRdflyveDvaeaillvl 226
                 ++  r +g +   +s   p +ir++ +     + +l++g+   d++ ++ +a+ il ++
  EEA18553.1 852 IIPGRrRGSKLwnPSEATPLMIRSASKDStGALPILDTGRDTCDWIEADTLADTILQLA 910
                 9955557766567*************977789*********************999775 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.0   1.3e-06     0.003      14      66 ..     553     608 ..     542     609 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 1.3e-06
  PP-binding  14 pleeidpdtdlfdlGlDSllavellaaleeefgv.....eiplsdlfehptlaelaay 66 
                 + e+  ++td+f  G+DSl+a+ l + + + +++     e ++  +f++ + ++la++
  EEA18553.1 553 EIED--VTTDFFTAGMDSLQAIHLRGVIIKNLDLggresECTSMIVFDCGNTQRLARR 608
                 4444..8*********************999977777889999999999999999987 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   1.5e-05     0.033       2     162 ..     662     839 ..     661     861 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.5e-05
   3Beta_HSD   2 vtGgaGFlGralvkeLvrleelkevrvlD...........lrespelleelskvnvkk..viegDvtdkdk.leea..legvdvvi..hlaslvdvagk 82 
                 +tG +GFlG+++  +Lv   ++ +v ++            +r + +l+ + +++  +k   +++D+t+++  l+ a   + +++++  +++++  v   
  EEA18553.1 662 LTGVTGFLGAHILAALVASSSVSKVYAFMrpnseakqtplVRLERSLQAKGFSISLNKviPLYADITEENFgLKTAemYKTMKLLVthVIHCAWAVNFA 760
                 79************************9999999999999988888888787777777766899****99853443311344443322135666666664 PP

   3Beta_HSD  83 ltedeimkvnvkGTrnvleacvkagvr.vlvYtSsaevvgpnslgeeilngdEeleyeslhqdaypesKalaEklvlkaNg 162
                 ++     +  + G +n+l+  ++++ + +++++Ss++ +   + g + + +      +s+ +  y++sK + E++v +a  
  EEA18553.1 761 IQLT-AFEPQLLGLHNLLAFGLESDRNaRVLFCSSIGTAQA-TPGTATIASAMLPSFDSCSSMGYSQSKLVGEHIVESATK 839
                 4444.7789999*********9998762688******9998.5566666455566677788888**********9998854 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   2.8e-05     0.062       3     122 ..     660     779 ..     658     812 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 2.8e-05
                 EEEETTTSHHHHHHHHHHHHHH.S-EEEEE-SS..--HHHH...HHHHHHHHTT-.....EEEE----TT-HHHHHHHHHHHHHHSS---EEEE----- CS
          KR   3 ylitGGlGgLGlelarwlaekg.arhlvllsRsaaadedsk...aliaelealga.....evevvaaDvsdkdavealleeikaeeppikGvihaAgvl 92 
                 +++tG +G LG ++   l+++   +++  + R  +++++++   +l ++l+a+g      +v  + aD+++++   ++ e +k+ +  ++ vih+A ++
  EEA18553.1 660 VILTGVTGFLGAHILAALVASSsVSKVYAFMRP-NSEAKQTplvRLERSLQAKGFsislnKVIPLYADITEENFGLKTAEMYKTMKLLVTHVIHCAWAV 757
                 789*************99987768899999988.333333322246677888888666666777889********9**99999999**********998 PP

                 ----TTT--HHHHHHHHTTTTHHHHHHHHH CS
          KR  93 rdklleemtaedleqvlapKvkGawnLhel 122
                 + +           ++++p + G++nL  +
  EEA18553.1 758 NFAIQL--------TAFEPQLLGLHNLLAF 779
                 765432........3455666666665555 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   5.8e-05      0.13       2     228 ..     662     901 ..     661     919 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 5.8e-05
                    EETTTSHHHHHHHHHHHHC..T-CCEEEEEEESS-TTH...HHHHCTTT...TTGC.CEEEEE--TT-HHHHHHHHHHHT.....-SEEEE--S-- CS
  GDP_Man_Dehyd   2 iTGiaGfiGsylaelLlek..gyevhgivrrsssfntg...riehlakdpkeelee.nlklhkgDltDssslerllaevq.....pdevynLAAqs 86 
                     TG++Gf G++++  L++     +v+ ++r +s+ + +   r+e+  + + ++++  ++   ++D+t+++   +  + ++     ++ v++ A   
     EEA18553.1 662 LTGVTGFLGAHILAALVASssVSKVYAFMRPNSEAKQTplvRLERSLQAKGFSISLnKVIPLYADITEENFGLKTAEMYKtmkllVTHVIHCA--W 755
                    6***************98733579999999777766551116666566666555533677789999998754444443331112256677755..3 PP

                    -HHHHTTSHHHHHHHHTHHHHHHHHHHHHCT..TTSEEEEEEEGGGG-S-SSSSB-TT......S----..-SHHHHHHHHHHHHHHHHHHHH--- CS
  GDP_Man_Dehyd  87 hVdvsfekPeytaevnvlGtlrLLeairalglekkvrfyqaStsEvYGkvqevpqtEt......tpfyP..rsPYaaaKlyadwivvnyreayglf 174
                    +V+  ++   + +e ++lG ++LL    +   ++++r+++ S+    G++q++p t t        f+      Y+ +Kl+ ++iv++  ++    
     EEA18553.1 756 AVNFAIQ--LTAFEPQLLGLHNLLAFGLE--SDRNARVLFCSS---IGTAQATPGTATiasamlPSFDScsSMGYSQSKLVGEHIVESATKNGANA 844
                    4444444..57788888999999988755..456788888887...48888888766544333322332225569999999999988877755544 PP

                    EEEEEE-EEESTTS-TT..SCCCHHHHHHHHHHTTS.-C-EECTTTT-EEEEEEHHH CS
  GDP_Man_Dehyd 175 avngilfnhesprrget..fvtrkitravarialgk.qevlylGnldakRdwghvkD 228
                    +v  i     + rrg +   + +  ++++  + ++     ++l  ++ + dw  ++ 
     EEA18553.1 845 TVLRIGQIIPGRRRGSKlwNPSEATPLMIRSASKDStGALPILDTGRDTCDWIEADT 901
                    444444456777777763234555555555555554233445567777777777665 PP

>> VirE1  Single-strand DNA-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.16   3.6e+02      31      60 ..     472     501 ..     468     503 .. 0.89
   2 ?    7.1   0.0    0.0025       5.7      33      53 ..     525     545 ..     515     547 .. 0.89
   3 ?   -4.1   0.1         8   1.8e+04       5      15 ..     643     653 ..     642     655 .. 0.81

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.16
                 -TTTTTS-HHHHHHHHHHHHHHT-----XX CS
       VirE1  31 nhqsnGftsLDLemieLenfvLrCPLPeen 60 
                 n +s  f  ++ em+ +  + ++CPL + n
  EEA18553.1 472 NSHSESFSQINREMVTILPMDVECPLTDKN 501
                 56789999******************9988 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0025
                 TTTTS-HHHHHHHHHHHHHHT CS
       VirE1  33 qsnGftsLDLemieLenfvLr 53 
                  sn   sL L ++eLen++L+
  EEA18553.1 525 SSNKVQSLQLTILELENWILE 545
                 68999*************995 PP

  == domain 3  score: -4.1 bits;  conditional E-value: 8
                 XXXXXXXXXXX CS
       VirE1   5 kLnanknmPvl 15 
                 k n+n++ P +
  EEA18553.1 643 KRNVNRTLPTS 653
                 679*****987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1032 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       463  (0.0258241); expected 358.6 (0.02)
Passed bias filter:                      452  (0.0252106); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.81u 0.32s 00:00:01.13 Elapsed: 00:00:00.48
# Mc/sec: 6456.42
//
Query:       EEA18554.1  [L=373]
Description: oxidoreductase, 2OG-Fe(II) oxygenase family, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.4e-13   49.3   0.0    1.6e-12   47.8   0.0    1.8  2  2OG-FeII_Oxy  2OG-Fe(II) oxygenase superfamily
    0.00033   21.4   0.0    0.00058   20.6   0.0    1.3  1  DIOX_N        non-haem dioxygenase in morphine synthesis N-te


Domain annotation for each model (and alignments):
>> 2OG-FeII_Oxy  2OG-Fe(II) oxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.8   0.0   1.8e-16   1.6e-12       6     101 .]     207     312 ..     202     312 .. 0.79
   2 ?   -3.0   0.0       1.2   1.1e+04      33      55 ..     324     346 ..     323     366 .. 0.65

  Alignments for each domain:
  == domain 1  score: 47.8 bits;  conditional E-value: 1.8e-16
                   EEEEE-S---------EEEEEESSSEEEEEEE-TT---E.....EEE.......TEEEE----TTEEEEEE-HHHHHHTTS-S----EEE----GTG CS
  2OG-FeII_Oxy   6 vlnyypphpdpevilglgahtdaslltillqddvgglev.....fkd.......gkwlrvppvdnslivniGdallflsngryksvlHrVlpvnege 90 
                   vl y      ++ i+   +htd + lt+ ++++  gl+v     + +       ++wl+v+p ++  ivniGd + +++ng ++s+lHrV pv+   
    EEA18554.1 207 VLKY-HANSNTD-IIPQTPHTDLGSLTFVFSTT-PGLQVlppgvQ-QnlgayseSEWLYVEPRPGHAIVNIGDCITLMTNGVLRSALHRVGPVTGCA 299
                   4445.4443444.77779**********99988.99*99555541.1577776356***********************************999854 PP

                   S..EEEEEEEE-- CS
  2OG-FeII_Oxy  91 r..Rvsiayfiep 101
                      R+s+ay ++p
    EEA18554.1 300 MpeRYSMAYLMRP 312
                   456******9876 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.2
                   EEEEE-TT---EEEETEEEE--- CS
  2OG-FeII_Oxy  33 illqddvgglevfkdgkwlrvpp 55 
                   +l+  ++ g+ v+ +g+w+r + 
    EEA18554.1 324 PLIPKSTDGEDVLTSGTWIRKKF 346
                   56777778888877788988775 PP

>> DIOX_N  non-haem dioxygenase in morphine synthesis N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.6   0.0   6.4e-08   0.00058      16      87 ..      45     124 ..      34     147 .. 0.78

  Alignments for each domain:
  == domain 1  score: 20.6 bits;  conditional E-value: 6.4e-08
      DIOX_N  16 aavaeqlreAcrevGffyvvnhgvpe....elidelfeaareFFalPeeeKekl...aksp.sfrGysrlgeektdgkkl 87 
                  ++ + l e c + Gffy+  +  +     + +d++f+ ++e+F+ P e K  +   + s+ +  Gy++ g++ + ++k 
  EEA18554.1  45 TSERNLLLETCMNDGFFYLDLTHPNFasllAFVDATFNCSKELFDYPPEIKSLFdvdKISDlKVNGYKPKGRNVVGNGKD 124
                 556677899**********87765533355999*********************87655668*******99998877333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (373 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       217  (0.0121033); expected 358.6 (0.02)
Passed bias filter:                      214  (0.011936); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 2443.05
//
Query:       EEA18555.1  [L=401]
Description: phospho-2-dehydro-3-deoxyheptonate aldolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.2e-80  268.9   0.0    4.2e-80  268.5   0.0    1.1  1  DAHP_synth_1  DAHP synthetase I family


Domain annotation for each model (and alignments):
>> DAHP_synth_1  DAHP synthetase I family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  268.5   0.0   2.4e-84   4.2e-80      16     274 ..      53     352 ..      41     353 .. 0.94

  Alignments for each domain:
  == domain 1  score: 268.5 bits;  conditional E-value: 2.4e-84
                   TCSEEEEEEESC-S-HHHHHHHHHHHHHHHHHHTTTEEEEEESSSC-S.SSTTS-SHTTHHHTHHHHHHHHHHH....................... CS
  DAHP_synth_1  16 ddrllviaGPCsiedpeaaleyAerlkklgeklkddleiimrayfeKpRrstvgfkGlindpdlkilsrikkel....................... 89 
                   ddrl+v++GPCsi+d +aaleyA  l++++e++  +l+++mr+y eKp rstvg+kGli dpd    ++ ++                         
    EEA18555.1  53 DDRLMVVVGPCSIHDTNAALEYASLLAQAAERHRRELVVVMRVYIEKP-RSTVGWKGLIHDPDY--AQDLENSNnssapdlskgvstarkvmlevak 146
                   99**********************************************.*************64..333333333458999**************** PP

                   .T-EEEEEESSCCTHHHHHHHESEEEE-CTCTTBHHHHHHHHTTSSEEEEEE-TT....HHHHHHHHHHHHHHHTTE.........EE--EEEEEEE CS
  DAHP_synth_1  90 .glpiatevldpisvqyladvvdiiqiGArttesqdllelasglskpvglKngtd....vaidemkaaaekilflgv.........etkgiilcerg 172
                    glp+ate+l+p  v +l d+v+++ iGArttesq+++e+as + +p g+Kngtd    vaid+mkaa+ ++ ++gv           +g+++++++
    EEA18555.1 147 mGLPVATELLNPLLVYFLDDIVSLGVIGARTTESQTHREMASDMPMPMGIKNGTDgglkVAIDAMKAASRPHTVVGVdedaglayhISRGNPDTFVI 243
                   *************************************************************************************999********* PP

                   EEEST.SSSSSCHCHHHHHHHHHHCTSS.-EEEESCHHHTTCGGGGHHHHHHHHHHHHHTT..ESEEEEEBBSSCCC-SST...GGGGBBCTCBHHH CS
  DAHP_synth_1 173 lrggk.ktnrdvedvaavkilkeetgkl.pvmvDvsHansrkdykrqkkvlklakaaiaaG..iaGvmiEshlnpgkalsd...gkqalkygksetd 262
                   lrgg  ++n++ e+++a+++++  +gk   ++vD+sH+ns+kdy++q  v+++ + +ia+G  i GvmiEs++n+g+++++   +k  lkyg+s+td
    EEA18555.1 244 LRGGSqGPNFSPEHIQAAEAELIRAGKKpAIVVDCSHGNSSKDYRNQGSVAACLAGQIAVGapIMGVMIESNINEGRQDVPdkgSKGCLKYGVSITD 340
                   ******************988766655559***************************************************8877778********* PP

                   HHHHHHHHHHHH CS
  DAHP_synth_1 263 acilkeltelll 274
                    c++++ te +l
    EEA18555.1 341 GCVGWNETESIL 352
                   ******999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (401 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       490  (0.02733); expected 358.6 (0.02)
Passed bias filter:                      435  (0.0242624); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.34s 00:00:00.96 Elapsed: 00:00:00.56
# Mc/sec: 2169.08
//
Query:       EEA18556.1  [L=626]
Description: multicopper oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.7e-41  139.3   0.1    5.7e-41  139.3   0.1    2.6  3  Cu-oxidase_3  Multicopper oxidase
      4e-37  127.0   9.7    3.3e-30  104.6   2.4    3.7  3  Cu-oxidase_2  Multicopper oxidase
    1.1e-24   87.4   0.0    3.3e-24   85.8   0.0    1.9  2  Cu-oxidase    Multicopper oxidase


Domain annotation for each model (and alignments):
>> Cu-oxidase_3  Multicopper oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.3   0.1   9.6e-45   5.7e-41       3     118 ..     100     216 ..      98     217 .. 0.95
   2 ?   -3.9   0.1       2.3   1.4e+04      34      44 ..     428     438 ..     414     443 .. 0.60
   3 ?    0.0   0.2      0.14   8.1e+02      64     107 ..     532     581 ..     504     588 .. 0.57

  Alignments for each domain:
  == domain 1  score: 139.3 bits;  conditional E-value: 9.6e-45
                   EEEEEECTTEESEEEEEECTSSBS-EEEEETT-EEEEEEEE-S...SS-B-EEEET--S-GG.....GSCSGGG-B-TT-EEEEEEE--S-SEEEEE CS
  Cu-oxidase_3   3 tektvsplggterevitvNgqfpgptievregdtvvvnvtNkl...dentsihwhGlqqrktswmDGvpgvtqcpiqpgesftyrftvkqqagtlwY 96 
                   + +t +p+g++ r+++++Ngq+pgp ie+++gd ++v+v+N+l   de+tsihwhGl+q +t+++DGvpg+tqcpi+pg++ftyrf++++  g+ wY
    EEA18556.1 100 APGTLAPDGYQ-RQMLLINGQYPGPLIEANWGDWIEVTVSNSLqdlDEGTSIHWHGLRQYGTQYADGVPGLTQCPIAPGSNFTYRFRADH-VGSSWY 194
                   66788999999.******************************99999*******************************************.****** PP

                   EE--TTHHHTT-EEEEEEE-HH CS
  Cu-oxidase_3  97 hshlslqqaaGlaGaiiiedke 118
                   hsh+s+q ++Gl+G+++ + ++
    EEA18556.1 195 HSHYSAQLTSGLVGPMVFYGPK 216
                   *******99*******998765 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 2.3
                   T-EEEEEEEE- CS
  Cu-oxidase_3  34 gdtvvvnvtNk 44 
                   ++t+++++ N 
    EEA18556.1 428 DQTITIHINNT 438
                   34555555554 PP

  == domain 3  score: 0.0 bits;  conditional E-value: 0.14
                   ...GSCSGGG-B-.......TT-EEEEEEE--S-SEEEEEEE--TTHHHTT CS
  Cu-oxidase_3  64 mDGvpgvtqcpiq.......pgesftyrftvkqqagtlwYhshlslqqaaG 107
                    DG    +++pi+       +  + + +ft ++  g   +h h++++   G
    EEA18556.1 532 WDGTIINSENPIRrdttllpASGHLVVQFTTDN-PGVWPFHCHVAWHVSTG 581
                   566666666666511111103445667788777.78888888888875555 PP

>> Cu-oxidase_2  Multicopper oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.6   0.1   5.8e-09   3.5e-05      31     132 ..     121     211 ..     101     214 .. 0.85
   2 ?   -0.3   0.1      0.14   8.2e+02      27      56 ..     412     445 ..     390     463 .. 0.63
   3 !  104.6   2.4   5.5e-34   3.3e-30      28     136 ..     475     591 ..     449     592 .. 0.86

  Alignments for each domain:
  == domain 1  score: 23.6 bits;  conditional E-value: 5.8e-09
                   SSEEEEEETTEEEEEEEEE-SSS...-EEEEESS-EEEEEEEEECCCCCCTCCSSGCCGSSCBSEEEE-TTEEEEEEEES.S-EEEEEEESSHHHHH CS
  Cu-oxidase_2  31 ntnvitlpkgevveiviqnntkl...pHPfHlHGhdfqvlgrgpgndpeedpksynlenpvrrdtvqvppggwvairfkadnpGvwllHCHilwHld 124
                     + i+++ g+++e+++ n+ +      ++H+HG + +  +   g              p+      + pg+++++rf+ad+ G   +H+H    l+
    EEA18556.1 121 PGPLIEANWGDWIEVTVSNSLQDldeGTSIHWHGLRQYGTQYADGV-------------PG-LTQCPIAPGSNFTYRFRADHVGSSWYHSHYSAQLT 203
                   467899999**********999987768*******88888777777.............33.34568899*************************** PP

                   TT-EEEEE CS
  Cu-oxidase_2 125 qGmalqfv 132
                   +G+++ +v
    EEA18556.1 204 SGLVGPMV 211
                   ***99876 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.14
                   CTTTSSEEEEEET...TEEEEEEEEE-SSS.-EE CS
  Cu-oxidase_2  27 efsentnvitlpk...gevveiviqnntkl.pHP 56 
                   +++++ +v ++p    ++++ i i+n+ +   H+
    EEA18556.1 412 PLNTTSPVTRIPAppaDQTITIHINNTKNEtGHS 445
                   5555555555555556888888888877663344 PP

  == domain 3  score: 104.6 bits;  conditional E-value: 5.5e-34
                   TTTSSEEEEEETTEEEEEEEEE-SSS-...........EEEEESS-EEEEEEEEECCCCCCTCCSSGCCGSSCBSEEEE-TTEEEEEEEES.S-EEE CS
  Cu-oxidase_2  28 fsentnvitlpkgevveiviqnntklp...........HPfHlHGhdfqvlgrgpgndpeedpksynlenpvrrdtvqvppggwvairfkadnpGvw 113
                    +++ nv+ + + +vv+iv +n+   p           HP+HlHGhd qvl+ g g++   d + +n enp+rrdt+ +p++g+++++f++dnpGvw
    EEA18556.1 475 SDPEWNVYSTGNSSVVRIVWENQKVDPsdpnfynltftHPMHLHGHDYQVLSYGFGEW---DGTIINSENPIRRDTTLLPASGHLVVQFTTDNPGVW 568
                   457889999999**********8888445567777777*******************6...6667888***************************** PP

                   EEEESSHHHHHTT-EEEEEEECH CS
  Cu-oxidase_2 114 llHCHilwHldqGmalqfvvrpd 136
                    +HCH++wH+++G+ +++++rpd
    EEA18556.1 569 PFHCHVAWHVSTGFLINILERPD 591
                   ********************987 PP

>> Cu-oxidase  Multicopper oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.8   0.0   5.6e-28   3.3e-24       4     158 ..     226     385 ..     223     386 .. 0.87
   2 ?   -3.4   0.0       1.5   8.9e+03      84     135 ..     514     572 ..     512     579 .. 0.63

  Alignments for each domain:
  == domain 1  score: 85.8 bits;  conditional E-value: 5.6e-28
                 EEEEEEETCBCTTSCBC.HSSCHCHHHHHTT--SEEEETTBSS.......C.....TTTTSGGGEEEEETTEEEEEEEESSS-BEEEEETSB-EEEEEE CS
  Cu-oxidase   4 vitlsDwyhkdakelekellasgkapadtppvpdavlingkggfnatladk.....dgaslatltvepgktyrlriinvsaddslnfsIeGHkltVvev 97 
                 +++lsD+yh   + l+++   +g   + +   +++ +ingk+ f+++  ++      ++   +++++pgk ++lr++nv+     +f+++ H ltV+  
  EEA18556.1 226 PVLLSDMYHPYYQRLVDRVNGNGS--EVHFAFSNNSVINGKMVFDCSSVTDgtpcvSNSGVSKFQFQPGKSHLLRLVNVGSSGLQFFTVDEHDLTVISN 322
                 689******999999994444433..3446679************9977757777788899************************************** PP

                 TCETTSEEEESCEEE-TTEEEEEEEEE-S.S..SEEEEEEEEGSSSCHHHHTTSEEEEEEEEST CS
  Cu-oxidase  98 DgvyvepvevdsldIavGqrysvlvtanq.a..pgnYwivasgrsnlieafengtaaailryse 158
                 D  +v+p++++s+ ++vGqr +v+v+ +  a   +nYw++a+  s+l+  +e+++++a + y+e
  EEA18556.1 323 DYIPVKPYTTNSVTLGVGQRADVIVHGKSgAdaERNYWMRANL-SVLCTLPEQPYGLAAIYYDE 385
                 **************************9654456********54.477999999*9999999986 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 1.5
                 EEEETSB-EEEEEE.....TCETTS...EEEESCEEE-TTEEEEEEEEE-SSSEEEEEEE CS
  Cu-oxidase  84 nfsIeGHkltVvev.....Dgvyve...pvevdsldIavGqrysvlvtanqapgnYwiva 135
                 ++ ++GH  +V        Dg+ ++   p + d+  + +     v +t+++ pg + +++
  EEA18556.1 514 PMHLHGHDYQVLSYgfgewDGTIINsenPIRRDTTLLPASGHLVVQFTTDN-PGVWPFHC 572
                 566666666666555555577766666677777766666666667777766.66666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (626 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       424  (0.0236488); expected 358.6 (0.02)
Passed bias filter:                      386  (0.0215294); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.44
# Mc/sec: 4288.46
//
Query:       EEA18557.1  [L=336]
Description: NAD dependent epimerase/dehydratase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.3e-18   64.9   0.0    1.2e-17   64.1   0.0    1.3  1  Epimerase        NAD dependent epimerase/dehydratase family
    7.5e-14   51.4   0.0    1.5e-13   50.4   0.0    1.4  1  3Beta_HSD        3-beta hydroxysteroid dehydrogenase/isomeras
    7.2e-10   38.8   0.0    1.3e-09   37.9   0.0    1.4  1  GDP_Man_Dehyd    GDP-mannose 4,6 dehydratase
    9.4e-10   38.1   0.0    2.9e-08   33.2   0.0    2.1  1  NAD_binding_4    Male sterility protein
    1.1e-08   35.2   0.0    3.4e-08   33.6   0.0    1.7  2  NAD_binding_10   NAD(P)H-binding
    5.5e-05   22.4   0.0    7.7e-05   22.0   0.0    1.1  1  Polysacc_synt_2  Polysaccharide biosynthesis protein
    0.00012   21.6   0.0    0.00026   20.5   0.0    1.6  2  adh_short        short chain dehydrogenase
     0.0011   18.9   0.1     0.0025   17.8   0.1    1.5  1  KR               KR domain
  ------ inclusion threshold ------
      0.013   16.0   0.0      0.028   15.0   0.0    1.5  1  F420_oxidored    NADP oxidoreductase coenzyme F420-dependent
      0.026   14.9   0.0       0.05   14.0   0.0    1.4  1  Retro_M          Retroviral M domain
      0.033   13.7   0.0       0.06   12.9   0.0    1.4  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
      0.054   12.6   0.0      0.081   12.0   0.0    1.2  1  RmlD_sub_bind    RmlD substrate binding domain
       0.11   12.1   0.0       0.31   10.6   0.0    1.8  2  NmrA             NmrA-like family


Domain annotation for each model (and alignments):
>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.1   0.0     9e-21   1.2e-17       1     234 [.       4     258 ..       4     264 .. 0.80

  Alignments for each domain:
  == domain 1  score: 64.1 bits;  conditional E-value: 9e-21
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC.....EEEE--TT-HHHHHHHHHHHT-SEEEE--S---HHHHHHSHHHHHHHHTHH CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl.....elveldltdrsalerlfkeeqpdavihlAavggvaassedpadfieknlqg 94 
                 +l+tG++Gf+ +++++ l  +gyev++  r +++  + r++         +  d+ +++a+++++k  + d+v+h A   + ++s   ++++++  + g
  EEA18557.1   4 VLLTGGSGFLAAHILDMLVHRGYEVVTTVRSEDKASKIREAYPnaklsVAIVPDIAQSDAFDEVVKVSGLDIVLHTASPFHFNWSDA-KSELLDPAITG 101
                 699*********************88877775555544444448999888899***********************99888888655.5899******* PP

                 HHHHHHHHHHH..TCTEEEEEEE.GGGGT..............SCSSSS..BSTCSTTS----SSHHHHHHHHHHHHHHHHHHHH..T-EEEEEEESEE CS
   Epimerase  95 tlnlleaarka..gvkrllflsS.sevYG..............kdaeqp..keettltgplkpnspYaaaKlageklveayaaqy..glnaiilrlfnl 172
                 t  +l+a++k+   vkr++  sS +++                +    p   ee +   +     +Y a+K+ +e+ ++++ ++   +++ +++ +  +
  EEA18557.1 102 TISILKAIKKYapSVKRVIVTSSfVSMLSaeglldpnkvysesDW--NPitYEEGL---SGSKVDAYRASKTVAERSAWNFVKEEkpNFDLVTICPPLV 195
                 ***********7778899999998777775666655554432211..233355555...44889*****************9999667*********** PP

                 ESTTS-TTSTTSHHHHHHHHHHT...TS.SSEEEETTST-EEEEEEHHHHHHHHHHHHHHHTT-ST CS
   Epimerase 173 yGprngegevsrvipalirkile...gk.qevtllgdgtalRdflyveDvaeaillvlehvdagdk 234
                 +Gp     +  + i    +++ e   gk ++ +l + g +   +++v+Dva a++++ e+++ag k
  EEA18557.1 196 FGPS-VSLSSLSAINTSNERFVEliqGKwKNEILPSLGVN--LWVDVRDVAFAHIAAFEKPEAGGK 258
                 ***9.66666677777777777666666667777776666..6*****************999864 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.4   0.0   1.1e-16   1.5e-13       2     248 ..       6     262 ..       5     270 .. 0.72

  Alignments for each domain:
  == domain 1  score: 50.4 bits;  conditional E-value: 1.1e-16
   3Beta_HSD   2 vtGgaGFlGralvkeLvrlee..lkevrvlDlrespelleelskvnvkkviegDvtdkdkleeale..gvdvvihlaslvdvagkltedeimkvnvkGT 96 
                 +tGg+GFl +++  +Lv+++   + +vr+ D++ +  ++e   + +    i  D+ + d  +e+++  g d+v+h+as       + + e+ +  + GT
  EEA18557.1   6 LTGGSGFLAAHILDMLVHRGYevVTTVRSEDKASK--IREAYPNAKLSVAIVPDIAQSDAFDEVVKvsGLDIVLHTASPFHFNWSDAKSELLDPAITGT 102
                 79****************98767899999998765..55666666666679************9753389************99*************** PP

   3Beta_HSD  97 rnvleacvka..gvrvlvYtSsaevvgpn.slgeeilngdEeleyesl........hqdaypesKalaEklvlkaNgrtlkngg.rlyTcaLRpagiyG 183
                  ++l+a +k   +v++++ tSs   +     l ++     E+   + +         +day  sK +aE+    a +  +k+ + ++  + + p  ++G
  EEA18557.1 103 ISILKAIKKYapSVKRVIVTSSFVSMLSAeGLLDPNKVYSESDWNPITyeeglsgsKVDAYRASKTVAERS---AWN-FVKEEKpNFDLVTICPPLVFG 197
                 *******986448********97555442022222222233333333311123344678888888888874...444.455555577777778****** PP

   3Beta_HSD 184 egdkllvpllkqlaklglalfkigdeev.......lsdrvYvgNvawahilAaralqdpkkkssvagqayfi 248
                 +  +l + ++ ++ + +   +  g+ ++       ++ +v v  va ahi A  +       +++ g+ +f+
  EEA18557.1 198 PSVSLSSLSAINTSNERFVELIQGKWKNeilpslgVNLWVDVRDVAFAHIAAFEK-------PEAGGKRFFC 262
                 **999988888888888777777765442222222456999*********99754.......3455666665 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.9   0.0   9.7e-13   1.3e-09       1     129 [.       5     124 ..       5     126 .. 0.86

  Alignments for each domain:
  == domain 1  score: 37.9 bits;  conditional E-value: 9.7e-13
                    EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHHHHT-SEEEE--S---HHHHTTSHH CS
  GDP_Man_Dehyd   1 LiTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkgDltDssslerllaevqpdevynLAAqshVdvsfekPe 96 
                    L TG++Gf  ++++++L+++gyev+ +vr +++  +++i++ + + k +       +  D+  s++ +++++    d v++ A   h + s  k+e
     EEA18557.1   5 LLTGGSGFLAAHILDMLVHRGYEVVTTVRSEDK--ASKIREAYPNAKLS-----VAIVPDIAQSDAFDEVVKVSGLDIVLHTASPFHFNWSDAKSE 93 
                    78***********************99987766..67999999765443.....35667********************************99965 PP

                    HHHHHHTHHHHHHHHHHHHCT..TTSEEEEEEE CS
  GDP_Man_Dehyd  97 ytaevnvlGtlrLLeairalglekkvrfyqaSt 129
                      ++  ++Gt+ +L+ai+++   + +r++ +S+
     EEA18557.1  94 -LLDPAITGTISILKAIKKYAP-SVKRVIVTSS 124
                    .67999*************974.4556666665 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.2   0.0   2.1e-11   2.9e-08       1     235 [.       6     229 ..       6     246 .. 0.72

  Alignments for each domain:
  == domain 1  score: 33.2 bits;  conditional E-value: 2.1e-11
                    EE-TTSHHHHHHHHHHHHHS-.TEEEEEE-SSSHHHHHHHHHHHT-SS-HHHHHHHHHTTTEEEEE--TTSGGGG--HHHHHHH..HHH--EEEE- CS
  NAD_binding_4   1 lTGaTGFLGkvLlekLLrttpevkiyllvRaksgesaeeRleeelekkelfsallkelaerikvveGDlseprlGLseedlqel..aeevdviihs 94 
                    lTG++GFL++++l  L+ +    +++  vR++++   + +++e+  + +l            ++++ D+++++      +++e+  ++ +d+++h 
     EEA18557.1   6 LTGGSGFLAAHILDMLVHRGY--EVVTTVRSEDK---ASKIREAYPNAKL-----------SVAIVPDIAQSD------AFDEVvkVSGLDIVLHT 79 
                    8****************9987..8********88...6777444333333...........367899***998......4444433689******* PP

                    -SS-S.ST..TSSEEHHHHHHHHHHHHHHHTSSS--..-EEEEEEGGGTTS-TTT--.SSS-H......HHH--EEEETTTCCCHHHHHHHHHHHH CS
  NAD_binding_4  95 aAtvnfde..pykellrvNveGtrevlelakklkkl.kvllhvSTayvngeregeve.ekvyeegekeekldederaklkglpntYeqsKalaEkl 186
                    a   +f+     +ell++ ++Gt  +l+  kk +   k ++  S+ ++    eg ++ +kvy   e++    + e+  +++  ++Y  sK +aE+ 
     EEA18557.1  80 ASPFHFNWsdAKSELLDPAITGTISILKAIKKYAPSvKRVIVTSSFVSMLSAEGLLDpNKVY--SESDWNPITYEEGLSGSKVDAYRASKTVAERS 173
                    **998875327788*****************9877635666666655555555544313444..4677777888889999999***********98 PP

                    HHHHHHHH..---EEEEEE-EEE-.....-SSST---TTSHHHHHHHHHHHH-EEE CS
  NAD_binding_4 187 vrearrrs..glpvvivRpsiitg.....esktGwingsdlgirgllgliakgvlp 235
                      +  +++  ++ +v + p+ + g     +s + +  ++++ ++++ g  + ++lp
     EEA18557.1 174 AWNFVKEEkpNFDLVTICPPLVFGpsvslSSLSAINTSNERFVELIQGKWKNEILP 229
                    77666553116778999999999977775555544444445555555555555555 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.6   0.0   2.5e-11   3.4e-08       1     102 [.       8     128 ..       8     178 .. 0.73
   2 ?   -1.4   0.0       1.3   1.8e+03      87     107 ..     254     274 ..     237     291 .. 0.68

  Alignments for each domain:
  == domain 1  score: 33.6 bits;  conditional E-value: 2.5e-11
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHHCT.TTCEE...EE--TT-CCHHHHHHT..T-SEEEES-.......--TCCHHHH..... CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpeklaeleae.eglev...vegdvtdvedlaealk..gadaVvsal.......ggggkdeeg..... 77 
                     G++G  + ++++ l++r g+ev+  vR+++k+++++++ +++++   ++ d+ ++++  e++k  g d+V+ ++       +    d+++     
      EEA18557.1   8 GGSGFLAAHILDMLVHR-GYEVVTTVRSEDKASKIREAyPNAKLsvaIVPDIAQSDAFDEVVKvsGLDIVLHTAspfhfnwS----DAKSelldp 97 
                     9****************.5**************998555666541124558899999***9977799*******66644331....333344555 PP

                     ....HHHHHHHHHH..CT--EEEEEEETTTT CS
  NAD_binding_10  78 ....aknivdaake..agvkRfvlvsaigvg 102
                         +++i++a k+    vkR+++ s++ + 
      EEA18557.1  98 aitgTISILKAIKKyaPSVKRVIVTSSFVSM 128
                     6688*********84357********97554 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 1.3
                     HCT--EEEEEEETTTTSGCGC CS
  NAD_binding_10  87 eagvkRfvlvsaigvgdevpg 107
                     eag kRf ++s+  +++e++ 
      EEA18557.1 254 EAGGKRFFCMSGKFSNREIAA 274
                     589999999998777766443 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.0   0.0   5.6e-08   7.7e-05       1     128 [.       4     124 ..       4     128 .. 0.87

  Alignments for each domain:
  == domain 1  score: 22.0 bits;  conditional E-value: 5.6e-08
                      EEEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH......-TTEEEE....E--TT-HHHHHHHTT..T-SEEEE------HHHHH CS
  Polysacc_synt_2   1 vlvtGagGsiGselvrqilkkkpkkiillerdElklyeiekeleeelkkkklkveivpvigdvrdkerlekaleelkvdvvfhaAAlKhVPlve 94 
                      vl+tG++G +  ++++ ++++   +++   r+E k  +i++ +     + kl+   v+++ d+++++  +++++  + d+v+h+A   h    +
       EEA18557.1   4 VLLTGGSGFLAAHILDMLVHRGY-EVVTTVRSEDKASKIREAY----PNAKLS---VAIVPDIAQSDAFDEVVKVSGLDIVLHTASPFHFNWSD 89 
                      899*********99998888766.56677799*******9987....666774...56999****************************99877 PP

                      HSHHHHHHHHHHHHHHHHHHHHHT..T-SEEEEEEE CS
  Polysacc_synt_2  95 enpleaiktNvlgtenvieaaiea..gvkkvvliSt 128
                          e ++  ++gt ++++a +++   vk+v++ S+
       EEA18557.1  90 A-KSELLDPAITGTISILKAIKKYapSVKRVIVTSS 124
                      6.5799*************99987346999999885 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5   0.0   1.9e-07   0.00026       2     137 ..       3     125 ..       2     135 .. 0.79
   2 ?   -2.8   0.0       2.6   3.6e+03     146     180 ..     160     193 ..     156     196 .. 0.69

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 1.9e-07
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCSHHH CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfselseee 100
                  vl tG+s+ +   i + l+ +G++vv + rse+k+ ++ +   ++ +  +ai  D++++++ +++v+     + +ld++ + A+      f+   +++
  EEA18557.1   3 KVLLTGGSGFLAAHILDMLVHRGYEVVTTVRSEDKASKIREAYPNA-KLSVAIVPDIAQSDAFDEVVK-----VSGLDIVLHTASP-----FHFNWSDA 90 
                 599************************************9999986.66788999***9999888886.....4589999988887.....55555555 PP

                 HHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEG CS
   adh_short 101 wervievNltgvflltravlpamlkqssGrIvnvsSv 137
                   ++++  +tg++++ +a+ ++  + s  r++ +sS 
  EEA18557.1  91 KSELLDPAITGTISILKAIKKY--APSVKRVIVTSSF 125
                 6677777777777777776666..4566666666665 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 2.6
                 BHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEES CS
   adh_short 146 vaaYsAsKaavagltrslakelaptgirvnavaPG 180
                 v aY AsK   +  + ++ ke +p     ++++P+
  EEA18557.1 160 VDAYRASKTVAERSAWNFVKEEKPN-FDLVTICPP 193
                 5689999988777777777777664.666666665 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.1   1.8e-06    0.0025       3     145 ..       4     133 ..       2     136 .. 0.80

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 1.8e-06
                 EEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHT.T-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT- CS
          KR   3 ylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaeleal.gaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklleem 100
                 +l+tGG G L+ ++ ++l+++g + +v + Rs    ed++++i+e   +   +v +v+ D++++da  ++++        +  v+h+A  ++ +     
  EEA18557.1   4 VLLTGGSGFLAAHILDMLVHRGYE-VVTTVRS----EDKASKIREAYPNaKLSVAIVP-DIAQSDAFDEVVKVSG-----LDIVLHTASPFHFNWS--- 88 
                 79********************75.7778888....4445556666555277777776.*********9998775.....8889999987777654... PP

                 -HHHHHHHHTTTTHHHHHHHHHTTT..S--SEEEEEEEHHHHH--TT CS
          KR 101 taedleqvlapKvkGawnLhelled..esldffvlfSSiagllgsag 145
                   ++  ++l p ++G+  + +++++   s++ ++++SS  ++l + g
  EEA18557.1  89 --DAKSELLDPAITGTISILKAIKKyaPSVKRVIVTSSFVSMLSAEG 133
                 ..445679999999999999999998788999999999999988766 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.0   0.0     2e-05     0.028       6      48 ..       9      53 ..       4      91 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 2e-05
                   TTSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC......- CS
  F420_oxidored  6 GaGnmgealasgllaagaqpheivvansrnpekaeelaeelg......v 48
                   G+G +++ ++  l+++g   +e+v ++ r+++ka +++e++       +
     EEA18557.1  9 GSGFLAAHILDMLVHRG---YEVV-TTVRSEDKASKIREAYPnaklsvA 53
                   89***************...****.77*************986555540 PP

>> Retro_M  Retroviral M domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   3.6e-05      0.05      17      54 ..     111     150 ..     100     162 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 3.6e-05
     Retro_M  17 kispskkei...gamlsllqkegllmspsdlyspgswdpit 54 
                 k +ps k +    +++s+l  egll  p  +ys   w+pit
  EEA18557.1 111 KYAPSVKRVivtSSFVSMLSAEGLL-DPNKVYSESDWNPIT 150
                 56777666523356899******86.8*************9 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   4.3e-05      0.06       7     132 ..      14     128 ..      11     142 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 4.3e-05
                   HHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSEE.EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHHHHHHHH CS
  adh_short_C2   7 GraiAkalaeeGaevvltdlneeakkrveelaeelgaev.lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreefdraldvn 102
                   +++i   l  +G+evv t ++e+++++++e+  + + +v +  D+++ ++ +++v+     + +lDi+++ a   +    +  +++     + ld  
    EEA18557.1  14 AAHILDMLVHRGYEVVTTVRSEDKASKIREAYPNAKLSVaIVPDIAQSDAFDEVVK-----VSGLDIVLHTASPFHF---NWSDAK----SELLDPA 98 
                   5666778899**************88888888887766559999999888777775.....589******9977666...444444....4566677 PP

                   THHHHHHHHHHHHHCTSCCEEEEEEEGGGT CS
  adh_short_C2 103 lyslfllakaalplmkeggsivnlssvgae 132
                   ++++++++ka+++++ +  +++ +ss+ + 
    EEA18557.1  99 ITGTISILKAIKKYAPSVKRVIVTSSFVSM 128
                   789999999999999998888888877665 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   5.9e-05     0.081       2      59 ..       3      80 ..       2     111 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 5.9e-05
                   EEEEESTTSHHHHHHHHHCTTTSEEEEEE-TT....................T--TTSHHHHHHHHHHH--SEEEE-- CS
  RmlD_sub_bind  2 kilvtGanGqlGseLakqlaeeglevlaltre....................eldltdaeavaellkeakpdvvvnaA 59
                   k+l+tG++G l+ ++ + l ++g+ev+++ r+                      d+++++a +e++k    d+v ++A
     EEA18557.1  3 KVLLTGGSGFLAAHILDMLVHRGYEVVTTVRSedkaskireaypnaklsvaiVPDIAQSDAFDEVVKVSGLDIVLHTA 80
                   79***************************8888999999999999999998888999999999999999999999998 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00022      0.31       1      35 [.       4      38 ..       4     134 .. 0.76
   2 ?   -1.5   0.0       1.1   1.5e+03     180     218 ..     235     273 ..     209     279 .. 0.69

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00022
                EEESSTTSHHHHHHHHHHHHHT-EEEEEES-S-SH CS
        NmrA  1 IlviGaTGrqGksvvrallkaghkvralvRdtkse 35
                +l +G++G +++++ ++l+++g++v   vR +++ 
  EEA18557.1  4 VLLTGGSGFLAAHILDMLVHRGYEVVTTVRSEDKA 38
                6889**************************98432 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1.1
                 E.-HHHHHHHHHHHHHHHHHHHTTEEEEE-SEEE-HHHHH CS
        NmrA 180 l.daeeDiGafvikilkdprklkgkriklagntlsgneiv 218
                 l ++++D++ + i+++++p++  gkr    +   s  ei+
  EEA18557.1 235 LwVDVRDVAFAHIAAFEKPEA-GGKRFFCMSGKFSNREIA 273
                 257899999999999999876.455555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (336 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       495  (0.0276089); expected 358.6 (0.02)
Passed bias filter:                      485  (0.0270511); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.65u 0.36s 00:00:01.01 Elapsed: 00:00:00.55
# Mc/sec: 1833.40
//
Query:       EEA18558.1  [L=405]
Description: chorismate synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   6.7e-140  465.4   0.0   7.6e-140  465.2   0.0    1.0  1  Chorismate_synt  Chorismate synthase


Domain annotation for each model (and alignments):
>> Chorismate_synt  Chorismate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  465.2   0.0  4.3e-144  7.6e-140       1     327 []       8     378 ..       8     378 .. 0.94

  Alignments for each domain:
  == domain 1  score: 465.2 bits;  conditional E-value: 4.3e-144
                      SEEEEE-SCCSSEEEEEEE---BT-B--HHHHHHHHHHHTCTSSSSSSHHHCS-EEEEESSEETTEE-SS-EEEEEE-TTS-..SS..SSSTSB CS
  Chorismate_synt   1 lrvttfGeShgkalgavidgvpagleldeediqkeLdrRrpgqsklttqrkEkDeveilsGvfegktlGtpiallieNkdqrskdy..eeikev 92 
                      +rvtt+GeSh++++g+++dg+p+g++l+e diq +++rRrpgqs+ltt+r+EkD+vei sG++ g tlGtpial+++N+dqr+kdy  ++++ +
       EEA18558.1   8 FRVTTYGESHCHSVGCIVDGCPPGMALSEGDIQPQMTRRRPGQSALTTPRDEKDRVEIQSGIECGFTLGTPIALIVHNEDQRPKDYggSTMDLY 101
                      89************************************************************99**********************7778888* PP

                      E-TTSTCHHHHHHC-S.STHCCCCCTHHCHHHHHHHHHHHHHHHHT.TTEEEEEEEEEETTE...........................CHH.H CS
  Chorismate_synt  93 pRpgHADltyalkYgirdlrgggrsSaReTaarvaaGavakklLke.lgieivayvssigei...........................eke.a 157
                      pRp+HAD+ty +kYg+++++gggrsSaReT++rvaaGa+a+k+Lk  ++ieiva+vss+g+                            ek  +
       EEA18558.1 102 PRPSHADFTYLEKYGVKASSGGGRSSARETIGRVAAGAIAEKYLKLaHNIEIVAFVSSVGKEdlfppspeypsysrnpnflrligaitrEKVdE 195
                      *********************************************967************6666777777777777888888888887633335 PP

                      HHTT-BS-CCCHHHHHHHHHHHHHTT--B-EEEEEEEES--TT-SBTTTB-HHHHHHHHHHTSTTEEEEEETTGGGGGGSBHHHHS--EE.... CS
  Chorismate_synt 158 enpvrcpdeeaaeemeeaieeakkegdslGgvvevvvkgvpaGlGepvfdkldakLakalmsipAvkgveiGsGfeaaelkGseanDeiv.... 247
                       +pvrcpd+ea+++m+eaie +++++ds+Gg+v +v+++vp+GlGep+fdkl+akL++a+msipA+kg+eiGsGf ++e++Gs +nD+++    
       EEA18558.1 196 FAPVRCPDTEASQRMTEAIEVFRDKKDSIGGTVMCVIRNVPTGLGEPCFDKLEAKLGHAMMSIPATKGFEIGSGFGGCEVPGSVHNDPFIftpe 289
                      56****************************************************************************************9999 PP

                      ..........EESS-TTTTEETTEEBSS-EEEEEEE--SS--SSEEEEEBTTS-E-EEEE--S-S-S-THHHHHHHHHHHHHHHHHHHHH CS
  Chorismate_synt 248 ..........lrktnnaGGieGGisnGepivvrvavKpipsiakeqktvdletkeevelevkgrhDpcvvpravvvveamvalvladall 327
                                ++ktnn+GGi+GGisnG++i++r+a+Kp ++i ++q+t +++ +e   le+kgrhDpcvvprav++veam alv++dall
       EEA18558.1 290 vgeindkkrmTTKTNNSGGIQGGISNGADIYFRIAFKPPATIGQAQTTTKYDFEE-GVLEAKGRHDPCVVPRAVPIVEAMSALVIMDALL 378
                      888887766444******************************************9.*******************************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (405 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       336  (0.0187406); expected 358.6 (0.02)
Passed bias filter:                      318  (0.0177366); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.47
# Mc/sec: 2565.89
//
Query:       EEA18559.1  [L=437]
Description: monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.5e-10   38.6   0.0    2.6e-09   36.8   0.0    1.7  1  FAD_binding_3   FAD binding domain
      6e-05   22.4   0.8     0.0003   20.1   0.5    1.9  2  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
     0.0003   21.0   2.1     0.0004   20.6   0.1    2.3  2  NAD_binding_8   NAD(P)-binding Rossmann-like domain
     0.0014   17.4   0.5     0.0031   16.3   0.4    1.6  2  HI0933_like     HI0933-like protein
     0.0017   18.0   2.0     0.0029   17.2   2.0    1.4  1  DAO             FAD dependent oxidoreductase
     0.0018   17.2   0.2      0.046   12.6   0.3    2.1  2  Trp_halogenase  Tryptophan halogenase
     0.0024   17.2   0.2     0.0038   16.5   0.2    1.2  1  Thi4            Thi4 family
     0.0076   16.3   0.5      0.035   14.1   0.3    2.0  2  NAD_binding_9   FAD-NAD(P)-binding
     0.0089   15.3   0.3      0.015   14.6   0.3    1.3  1  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
       0.01   15.1   0.0      0.021   14.1   0.0    1.4  1  Amino_oxidase   Flavin containing amine oxidoreductase
      0.016   14.3   0.2       0.11   11.5   0.2    2.0  1  Lycopene_cycl   Lycopene cyclase protein
      0.094   11.8   1.1       0.17   10.9   1.1    1.3  1  FAD_binding_2   FAD binding domain
        0.1   13.2   0.6       0.37   11.4   0.2    2.2  3  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
       0.35    9.9   0.6        0.5    9.4   0.6    1.2  1  GIDA            Glucose inhibited division protein A


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.8   0.0   2.1e-12   2.6e-09       4     319 ..      13     328 ..      10     345 .. 0.78

  Alignments for each domain:
  == domain 1  score: 36.8 bits;  conditional E-value: 2.1e-12
                    EEEE--SHHHHHHHHHHHHT.THHEEEEESSSSSCCSSS--EEEHHHHHHHHHTT-HHHHHHHSEECCCCEEEEEEECCCCCEEEEEHHCHHCST- CS
  FAD_binding_3   4 VlIVGaGpaGlmlallLsea.GvrvvlvekrsttvvlpradglnqrtmellrqlGledrilaegapnelmgealynelsdtpkaradlelessper 98 
                    ++I+G+GpaGl +a  Ls    vr +l ek ++  + + +  +      +l+ lG +d+++ + ++n l +  l++ +++++ a+  l    ++ r
     EEA18559.1  13 IAIIGGGPAGLGAAIALSALpDVRITLYEKARELREVGAGISIGYNCWKVLELLGAADEVRGHLQQNVLHRNGLSGGIQRVKPAPSSLP--LKY-R 105
                    57***************9863599999*************************************9999999999999999988888888..333.3 PP

                    CEE--HHHHHHHHHHHHHHHT.EEETCSEEEECCEECCCCCCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHHHTGG.EEEEEEEEEEEEEEEEE CS
  FAD_binding_3  99 vtvypqteleriLvehaeerg.lqvrfktevesleqdeegvtaevrdketgeeetvrakYlvGaDGgrStvrktlgie.fegeetvyeagvldvlf 192
                     + +  ++l+ +Lv++    +   ++ +++++s+++ +   + + +  e+g+e   +a+ l+G DG rS vr +l  e  + + ++++++ l    
     EEA18559.1 106 SKRVRRSRLQAALVSK---VPpGIIQLNKKLVSIHDAG--TQGVHLTFEDGTE--TNADLLIGGDGIRSVVRTSLFPEhTTKFTGTTIWRALIPAK 194
                    45567899999**999...3337778888888654433..2344444445555..69*****************9877677777777777653333 PP

                    EC.-SCCCTTCCEEEEECCTTEE.......EEEECCE.TEEEEEEEEECCE-GGGSCCCHHHHHHHHHHHHHHTTSSCEEEEEEEEEEEEEEEEES CS
  FAD_binding_3 193 da.dlsdiveplvlilsaesrgv.......mviPlen.tlerfyvqvearaekeersekfteeevkarlreivgektldveieevsawtvaqrvae 279
                    +   + d+  +  + + ++              P ++  +++ ++ ++++ ++++++ ++   ++  r+r +      d   +e+sa+  + r+ +
     EEA18559.1 195 TLyHIHDLFPDTSWWHGPSGHCYfslvddpSEFPDSStSSSEQLMEISWGVPVTNERVNIHFMQYDPRVRDALSC-VPDGGWKEFSAFS-GPRLER 288
                    3347777777755555555554455666665667777788999**********************9999998764.3466777777774.567777 PP

                    SSEETTEEE-GGGTEEE-STTSHHHHHHHHHHHHHHHHHH CS
  FAD_binding_3 280 kyrkgrvflaGDAaHihpPtgGqGlNtaiqDavnLawkLa 319
                        ++v l GDA H  + + G G   a++D   La+++ 
     EEA18559.1 289 LVGWEKVALLGDASHPLSGAFGSGAAFALEDGWILARAIE 328
                    777889*************************888887664 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   0.5   2.3e-07    0.0003       3      58 ..      13     117 ..      12     160 .. 0.57
   2 ?    1.1   0.0      0.15   1.9e+02     201     239 ..     128     167 ..     125     173 .. 0.81

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 2.3e-07
                  EEEE--SHHHHHHHHHHHH.HTS-EEEEE........TTHCHHHCSHHHHCHHHHHHHHHHHHH.................................. CS
                  xxxxxxxxxxxxxxxxxxx.xxxxxxxxx........xxxxxxxxxxxxxxxxxxxxxxxxxxx.................................. RF
  Pyr_redox_2   3 vvviGgGpAGlaaaltlaq.agakvtlve........legtclnggcllskallgvaedaeias.................................. 57 
                  +++iGgGpAGl aa+ l++   +++tl+e          g   +  c+   +llg+a++ +  +                                  
   EEA18559.1  13 IAIIGGGPAGLGAAIALSAlPDVRITLYEkarelrevGAGISIGYNCWKVLELLGAADEVRGHLqqnvlhrnglsggiqrvkpapsslplkyrskrvr 110
                  79*****************66*******9554444333333333334443344444433333335555555555555555555555555555555555 PP

                  ......H CS
                  ......x RF
  Pyr_redox_2  58 ......e 58 
                         
   EEA18559.1 111 rsrlqaA 117
                  5555554 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.15
                  EESCEEEEEEETTE.EEEEEETTSCEEEESEEEE-S-EEE CS
                  xxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 201 klgtsvkeidgnge.klevvledgeeidadlvvvavGvrp 239
                  +l+++ + i + g+  ++++ edg+e +adl++ + G+r 
   EEA18559.1 128 QLNKKLVSIHDAGTqGVHLTFEDGTETNADLLIGGDGIRS 167
                  5666666777777667889**************9999875 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.6   0.1   3.1e-07    0.0004       1      30 [.      15      45 ..      15      47 .. 0.94
   2 ?   -2.8   0.2         6   7.6e+03       4      16 ..     306     318 ..     306     319 .. 0.85

  Alignments for each domain:
  == domain 1  score: 20.6 bits;  conditional E-value: 3.1e-07
                   EE--SHHHHHHHHHHHCC.TEEEEEE-SSSS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLaka.gfdvlllekrdr 30
                   I+G+G +Gl aA +L+   +++++l+ek++ 
     EEA18559.1 15 IIGGGPAGLGAAIALSALpDVRITLYEKARE 45
                   9****************88*********975 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 6
                    -SHHHHHHHHHHH CS
  NAD_binding_8   4 aGlsGlvaAylLa 16 
                    +G++G+ aA +L 
     EEA18559.1 306 SGAFGSGAAFALE 318
                    7999999999985 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.4   2.4e-06    0.0031       3      35 ..      13      46 ..      11      52 .. 0.90
   2 ?   -3.2   0.0         2   2.6e+03     184     217 ..      89     122 ..      87     139 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 2.4e-06
                 EEEE--SHHHHHHHHHH.HHTT--EEEE-SSSSS CS
  HI0933_like  3 viviGgGaAGlmaAisa.akrgkrVlllekakkl 35
                 +++iGgG+AGl aAi++ a  + r++l+eka++l
   EEA18559.1 13 IAIIGGGPAGLGAAIALsALPDVRITLYEKAREL 46
                 79**************97789*********9875 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2
                  T--EEEEEEES--EE--HHHHHCGGGTT-EEEEE CS
  HI0933_like 184 ghtivplrpalvpltlkesklklkelsGvslkav 217
                  g++ v++ p+  pl+++ +++++++l+ + +++v
   EEA18559.1  89 GIQRVKPAPSSLPLKYRSKRVRRSRLQAALVSKV 122
                  5666789999999999999999999987766655 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   2.0   2.3e-06    0.0029       2      33 ..      13      47 ..      12      55 .. 0.90

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 2.3e-06
                EEEECTSHHHHHHHHHHHHTT...EEEEESSSSTT CS
         DAO  2 vviiGGGiiGlstAyeLarrg...Vtllekgdiag 33
                ++iiGGG +Gl++A +L++ +   +tl+ek++++ 
  EEA18559.1 13 IAIIGGGPAGLGAAIALSALPdvrITLYEKARELR 47
                89***************999889*******98865 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.3   3.6e-05     0.046       2      57 ..      13      67 ..      12      75 .. 0.78
   2 ?    2.3   0.0     0.046        59     189     227 ..     145     183 ..     123     195 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 3.6e-05
                    EEEE--SHHHHHHHHHHHHHTTTSSEEEEEE-S.SS---SS-EE--THHHHTHHHHT CS
  Trp_halogenase  2 ivivGGGtaGwlaAaalakalkgklevtlvese.eigtvgvGeatipsirkllrlLg 57
                    i i+GGG+aG  aA+al+     ++++tl e++ e+  vg G +   +  k+l+lLg
      EEA18559.1 13 IAIIGGGPAGLGAAIALSALP--DVRITLYEKArELREVGAGISIGYNCWKVLELLG 67
                    89***************9988..69*****986367777777666555555555555 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.046
                     EEEETTS-EEE-SEEEE-SGGG-IIIIIIT---EEE-TT CS
  Trp_halogenase 189 slrledgreveadlfiDcsGfrgllieqaLktgfedwsd 227
                     +l+ edg+e +adl i   G r+ +  + + + +++++ 
      EEA18559.1 145 HLTFEDGTETNADLLIGGDGIRSVVRTSLFPEHTTKFTG 183
                     7999*******************9998888887777765 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.2   2.9e-06    0.0038      19      50 ..      12      43 ..       3      73 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 2.9e-06
                EEEEE--SHHHHHHHHHHHHCTTS-EEEEESS CS
        Thi4 19 DvvivGaGssGLtaayylakkpdlkvailers 50
                 ++i+G+G++GL aa  l+  pd+++++ e+ 
  EEA18559.1 12 CIAIIGGGPAGLGAAIALSALPDVRITLYEKA 43
                589**************************975 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.1   0.3   2.7e-05     0.035       1      35 [.      14      44 ..      14      52 .. 0.88
   2 ?   -0.8   0.0         1   1.3e+03     108     149 ..     119     159 ..     111     160 .. 0.70

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 2.7e-05
  NAD_binding_9  1 aivGaGprGlavlerLlarakkkspleitlfdpse 35
                   ai+G+Gp+Gl ++ +L a      +++itl++++ 
     EEA18559.1 14 AIIGGGPAGLGAAIALSALP----DVRITLYEKAR 44
                   8******************5....9******9954 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 1
  NAD_binding_9 108 larlpegvtvevhraevvdleeradg.qavlladgaslaadaV 149
                    ++++p g  +  ++++ v++++++++ ++++ +dg+++ ad +
     EEA18559.1 119 VSKVPPG--IIQLNKKLVSIHDAGTQgVHLTFEDGTETNADLL 159
                    4555554..445677888888887662688889***9999975 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.3   1.1e-05     0.015       2      21 ..      15      34 ..      14      47 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 1.1e-05
  Pyr_redox_3  2 IiGaGPaGlaaaielkkagl 21
                 IiG+GPaGl+aai+l  +  
   EEA18559.1 15 IIGGGPAGLGAAIALSALPD 34
                 9*************988765 PP

>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   1.6e-05     0.021     210     257 ..     112     160 ..      94     161 .. 0.93

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 1.6e-05
                    HHHHHHHHHTTTTEEEETSEEEEEEEE.ETTCEEEEETTSTEEEESEEE CS
  Amino_oxidase 210 sqlpealaeelrgldirlntrVkeikr.egdgvtvtledgevveaDaVv 257
                    s+l  al ++ +++ i+ln+++ +i+  +  gv +t+edg++++aD  +
     EEA18559.1 112 SRLQAALVSKVPPGIIQLNKKLVSIHDaGTQGVHLTFEDGTETNADLLI 160
                    578999999******************99999**************876 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.2   8.7e-05      0.11       2     143 ..      13     167 ..      12     183 .. 0.67

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 8.7e-05
  Lycopene_cycl   2 vvviGaGpAglslAarlteakpglkvvlieaspsllfpnn.....y.vWsdefedlga.......leecvehsW.sgtivylddgkkillg..... 78 
                    +++iG+GpAgl  A  l +a p+++++l e + +l   +      y  W   +  lga       l++ v h+      ++               
     EEA18559.1  13 IAIIGGGPAGLGAAIAL-SALPDVRITLYEKARELREVGAgisigYnCWKVLE-LLGAadevrghLQQNVLHRNgLSGGIQRV-------Kpapss 99 
                    78************999.999******99988777433221111144666543.34432233344444443332011122222.......123333 PP

  Lycopene_cycl  79 ..raY..grvsskrlkeellerlvengvklleakvesveeeeageslvvleggrkirarlvvdarglas 143
                      ++Y  +rv+++rl++ l  +++  g++ l+ k  s++++    +  + e+g + +a l + + g+ s
     EEA18559.1 100 lpLKYrsKRVRRSRLQAALVSKVP-PGIIQLNKKLVSIHDAGTQGVHLTFEDGTETNADLLIGGDGIRS 167
                    455553368999999999999999.89999999999999998888999999999999999998888655 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   1.1   0.00013      0.17       3      34 ..      14      46 ..      13      59 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00013
                   EEE--SHHHHHHHHHHHHTTT.-EEEEESSSGG CS
  FAD_binding_2  3 iViGsGlAGLaAAleaaeaGl.kvavvekeqef 34
                    +iG+G AGL AA++++     ++++ ek+ e 
     EEA18559.1 14 AIIGGGPAGLGAAIALSALPDvRITLYEKAREL 46
                   79**************99766699999998775 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.2   0.00029      0.37       2      35 ..      13      47 ..      12      69 .. 0.87
   2 ?   -2.9   0.0       8.4   1.1e+04      58      78 ..     128     146 ..     127     151 .. 0.63
   3 ?   -2.5   0.0         6   7.7e+03      38      52 ..     421     435 ..     413     436 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00029
                EEEECSSHHHHHHHHHHHHTT.SEEEEEESSSSSS CS
   Pyr_redox  2 vvvvGgGyiglElAgalaelg.kkVtvversdkll 35
                ++++GgG  gl +A al++l   ++t+ e + +l+
  EEA18559.1 13 IAIIGGGPAGLGAAIALSALPdVRITLYEKARELR 47
                79*****************9857999999999988 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 8.4
                 ECSEEEEEEEEETTSEEEEEE CS
   Pyr_redox  58 llntkveeiegsedgvesvkl 78 
                  ln+k+++i+  + +  +v+l
  EEA18559.1 128 QLNKKLVSIHDAGTQ--GVHL 146
                 589999999955544..4444 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 6
                 SSHHHHHHHHHHHHH CS
   Pyr_redox  38 lDeeaskilqeklek 52 
                 + ++++ki+q++l++
  EEA18559.1 421 YKNDIEKIWQNYLQQ 435
                 668999****99987 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.6   0.00039       0.5       2      32 ..      13      43 ..      12      90 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00039
                EEEE-SSHHHHHHHHHHHHT.T--EEEEES-G CS
        GIDA  2 viViGgGhAGceAAlaaarl.GakvlLithkl 32
                + +iGgG AG+ AA+a++ l  ++++L+ +k 
  EEA18559.1 13 IAIIGGGPAGLGAAIALSALpDVRITLY-EKA 43
                679*************876536777777.444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (437 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       308  (0.0171789); expected 358.6 (0.02)
Passed bias filter:                      294  (0.016398); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.48
# Mc/sec: 2730.11
//
Query:       EEA18560.1  [L=1573]
Description: pentafunctional polypeptide (AroM), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.1e-122  409.8   0.0   1.6e-122  409.2   0.0    1.2  1  EPSP_synthase    EPSP synthase (3-phosphoshikimate 1-carboxyv
   4.4e-100  334.2   0.1   6.8e-100  333.6   0.1    1.3  1  DHQ_synthase     3-dehydroquinate synthase
    8.8e-57  193.0   0.0    1.8e-56  192.0   0.0    1.6  1  DHquinase_I      Type I 3-dehydroquinase
    7.4e-39  133.4   0.0    9.4e-37  126.6   0.0    2.7  2  SKI              Shikimate kinase
    2.4e-23   82.2   0.0    7.2e-23   80.6   0.0    1.9  1  Shikimate_dh_N   Shikimate dehydrogenase substrate binding do
    8.2e-09   35.1   0.3      3e-08   33.3   0.1    2.1  2  SDH_C            Shikimate 5'-dehydrogenase C-terminal domain
    2.1e-08   34.2   0.0    6.2e-08   32.7   0.0    1.8  1  Fe-ADH_2         Iron-containing alcohol dehydrogenase
    6.9e-05   22.9   0.0     0.0002   21.4   0.0    1.7  1  Shikimate_DH     Shikimate / quinate 5-dehydrogenase
     0.0072   16.7   1.0        1.9    8.8   0.0    3.9  4  AAA_16           AAA ATPase domain
  ------ inclusion threshold ------
      0.013   16.0   0.0      0.041   14.4   0.0    1.9  1  AAA_18           AAA domain
      0.043   14.1   0.0       0.25   11.6   0.0    2.4  2  AAA_22           AAA domain
      0.049   13.7   0.0       0.22   11.6   0.0    2.1  2  AAA_14           AAA domain
      0.052   13.3   0.1       0.13   11.9   0.0    1.7  2  AAA_24           AAA domain
      0.054   13.8   0.0        0.3   11.3   0.0    2.3  2  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma


Domain annotation for each model (and alignments):
>> EPSP_synthase  EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  409.2   0.0  1.3e-125  1.6e-122       5     417 .]     399     832 ..     396     832 .. 0.94

  Alignments for each domain:
  == domain 1  score: 409.2 bits;  conditional E-value: 1.3e-125
                    S--EEEEE--B-HHHHHHHHHHHGGGBSSEEEES---SHHHHHHHHHHHHTT.EEEEEECTSEEEEEGTT..--EE-HHHHTT-GGGGGGHHHHHH CS
  EPSP_synthase   5 krlegevkvpGsksisnralllAaLaegestitnlLdseDvrsmlealreLgaeiikldeekevviveglggsfeapeelvldlgnsgtalrlLta 100
                    k+l+    +pGsksisnral+lAaL++g+++++nlL+s+D++ ml+al +Lga++  +++e+ev++v+g+gg+++a+  + l+lgn+gta+r+Lt+
     EEA18560.1 399 KDLNVVCAPPGSKSISNRALVLAALGSGTVRVKNLLHSDDTEVMLNALERLGAATFAWEDEGEVLVVNGNGGKMQAS-PTELYLGNAGTASRFLTS 493
                    677777899*******************************************************************9.7***************** PP

                    HHSEES....SEEEEE-SBTTCGS--HHHHHHHHHTT-EEEEETTEEEEEESEET...SS-BEEEEETSSTTHHHHHHHHHHHTTSBS..EEEEES CS
  EPSP_synthase 101 llalas....gevvLtGdesirkRPidrlldaLrqlGaeieveegenkaplkvkg...lklkgveikaevsSqqvtsllllaallaeg..ttelee 187
                    +++l +     + +LtG++++++RPi +l+daL+ +Ga++e++e+++++plk+ +   +k+++++++a+vsSq+v+sll++a+ +a++  t++l++
     EEA18560.1 494 VATLSGkgsvDYNILTGNNRMKQRPIGDLVDALTINGAQVEYLEKAGSLPLKIAAsggFKGGRINLAAKVSSQYVSSLLMCAP-YAKEpvTLKLVG 588
                    ***9666888899****************************************99999*************************.777769999999 PP

                    ..-TTHHHHHHHHHHHHHTT-EEEETTSSEEEEEE--SS..B--EEEE--B-HHHHHHHHHHHHHTT-EEEEES--GGGGHHH..HHHHHHHHTTE CS
  EPSP_synthase 188 ..lasepsiddtlkmlkkfgikietsgteesitvkGkek..lpgteyvvegDassAayflvaAaitggevtvenvginslqGdiealdeilekmga 279
                      ++s  +i++t  m+++fgi++++s+tee ++  ++ +  +p  eyv+e+DassA+y+l+ Aa+tg++ tv n+g  slqGd++++ e+l+ mg+
     EEA18560.1 589 grPISLSYIEMTTAMMRSFGIDVQKSTTEEWTYHIPQGSynNPP-EYVIESDASSATYPLAIAAVTGTTCTVPNIGSASLQGDARFAVEVLRPMGC 683
                    9999*********************9999966666777785666.*************************************************** PP

                    EEEEESTSEEEEEET...TS--BEEEEEBGSTTSBHGGGHHHHHH.....HHHTSBSEEEEEGSSSTTCCHHHHHHHTTT-EEEEETTEEEEEEEE CS
  EPSP_synthase 280 eitqeedasivvgps...glklkdvdietlpdeaptlavlaafae.....gttviegiaelrvketdrlaamateLrklGaeveeeedgliiipae 367
                    +++q++++++v gp       l +vd+e ++d+++ + vlaa+a+       t+i gia++rvke++r+ am  eL+k+G+ ++e +dgl+i + +
     EEA18560.1 684 KVEQTATSTTVTGPAdgvLRPLPNVDMEPMTDAFLGASVLAAIAQgeggnHATRIYGIANQRVKECNRIEAMRVELAKFGVVCREHPDGLEIDGID 779
                    ************999997788899*********************8887778***************************************55554 PP

                    E....EB-EEEE-TTSTTTTHHHHHHHHHSBSEEEEETTHHHHHHSSSHHHHH CS
  EPSP_synthase 368 k...qlkgaevesydDhRiamalalaglvaegeveiddiectdksfpefeekL 417
                        +   + v +ydDhR+a ++++++lva  ++ i + ec+ k++p++++ L
     EEA18560.1 780 RstlRHPAGGVFCYDDHRVAFSFSILSLVAPTPTLILEKECVGKTWPTYWDAL 832
                    444477889*****************************************976 PP

>> DHQ_synthase  3-dehydroquinate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  333.6   0.1  5.3e-103  6.8e-100       3     261 ..      76     354 ..      74     355 .. 0.98

  Alignments for each domain:
  == domain 1  score: 333.6 bits;  conditional E-value: 5.3e-103
                   EE-SSGGGCCHHHHHHHHHHHHHTT--TT-EEEEEESHHHHHHHHHHHHHBTT--EEEEEE-SHHHHHTTTSSSEEEEEETTEEEEEEEE---SEEE CS
  DHQ_synthase   3 vvpdgeksKsletlekildalleakleRksllialGGGvvgDlaGfvAatylRGvrfvqvPttllaqvDssvGgKtainlplgKNliGafaqPkavl 99 
                    +p+ge+sKs +  ++i d++l++ + R++++ialGGGv+gDl GfvAaty+RG+rfvqvPttlla+vDss+GgKtai++plgKNliGa++qP+ ++
    EEA18560.1  76 EIPPGENSKSRQGKADIEDWMLQQTCGRDTVIIALGGGVIGDLLGFVAATYMRGIRFVQVPTTLLAMVDSSIGGKTAIDTPLGKNLIGAIWQPHRIY 172
                   589********************************************************************************************** PP

                   EEGGGGGGS-HHHHHHHHHHHHHHHHHT-HHHHHHHHHHHHHHHC...........TTTHHHHHHHHHHHHHHHHHHHHHCCTTTTGGGGGGTTHHH CS
  DHQ_synthase 100 idlevLktLperelraGlaEviKyalikdeelfelleenaeallk...........eeeeealeeliarsievkaevveeDekekglralLnlGHti 185
                   id+++++tLpere+++G+aEviK+a+i+de+ f++le++a+a+lk              ++++++ i +s ++ka vv++De+e glr+lLnlGH+i
    EEA18560.1 173 IDIDFIDTLPEREFINGMAEVIKTAAISDEKEFAALEQHADAILKaarskpgkgrfDLVRQVVKDRIVASARHKAFVVTADEREGGLRNLLNLGHSI 269
                   ********************************************9********999668999*********************************** PP

                   HHHHHHHHTTTTS-HHHHHHHHHHHHHHHHHHTTSS-HHHHHHHHHHHHHTT---STTTT...........-HHHHHHHHTTCTTX CS
  DHQ_synthase 186 gHaiEallgyekllHGeaVaiGmvlaaelseklgllkkeeverllkllkklglpvslkel..........leveellealkkDkkv 261
                   gHaiEa+l++ ++lHGe+VaiGmv++++l+++lg+lk+ +v+r++k+l+k+glp+slk++          +++e++++ ++ Dkk+
    EEA18560.1 270 GHAIEAILSP-QVLHGECVAIGMVKELDLARYLGILKPVAVSRMVKCLSKYGLPTSLKDSrvrkhtagkhCSLEQMMANMALDKKN 354
                   **********.************************************************99*******999**************8 PP

>> DHquinase_I  Type I 3-dehydroquinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  192.0   0.0   1.4e-59   1.8e-56       4     227 ..    1052    1276 ..    1049    1278 .. 0.91

  Alignments for each domain:
  == domain 1  score: 192.0 bits;  conditional E-value: 1.4e-59
                   E--SSHH...HHHHHHHHHTTS-SEEEEEGGG-.TT.T......HHHHHHHHHHHHHHTTS-EEEE---GGGT-S.SSS-HHHHHHHHHHHHHCT- CS
  DHquinase_I    4 itgktle...eilaelesgkekaDlvElRlDllketse......aedvseeleelrstsdlpliftlrtkaeggrfkrkseeeylellrtaielga 90  
                   +t ++l+   ++l+ + sg   +D+vElR+Dllk++s+      ae+v+e+++  rs  +lp++ft+rt ++gg+f++++++++lel+  ai++g+
   EEA18560.1 1052 LTLTDLRdsgDLLRTVASG---SDAVELRVDLLKDPSSgngipsAEYVAEQISFYRSRVSLPIVFTIRTVSQGGKFPNDAHDAALELIMLAIRSGC 1144
                   5555666444667777777...9**********99988*******************88************************************* PP

                   SEEEEEGG-.HHGHHHHHHHHHHHTT-EEEEEEEESS----HH..HHHHHHHHHHHTT-SEEEEEE--SSHHHHHHHHHHHHHHHHHT-SS-EEEE CS
  DHquinase_I   91 dyvDvElteapeeskkrlieekreggtkvIvSyhdfegtpsae..elkallekmqalgaDivKiavmaksieDvlrllsltseakeekdeaplIam 184 
                   +++D+E+t  pe+  ++++e+k  ++ k+I+S+hd +g+  +   ++++ ++k+ ++g Di+K++ +a++ +D+++l +++ +a+++++++p+Ia+
   EEA18560.1 1145 EFIDLEIT-FPEDLLRKVAESK--AHAKIIASHHDPQGKLNWAngSWIQYYNKALQYG-DIIKLVGVAETLKDNTALREFKDWAEQAHPDVPVIAI 1236
                   *******5.6766445788888..9******************999************.**********************888888999****** PP

                   E-TTTTGHHHCHHHHHTB-EEEEESSS-..SSTT-EEHHHHHH CS
  DHquinase_I  185 amGelGkiSRilgevfGspvtfasleeakasapGqltarelre 227 
                   +mG++G++SR+l+ ++ +pv++++   + ++apGql+a+e+r+
   EEA18560.1 1237 NMGDKGQLSRMLNGFL-TPVSHPA--LPFKAAPGQLSAAEIRK 1276
                   ****************.*******..7788***********98 PP

>> SKI  Shikimate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0     0.043        56      49      73 ..      91     115 ..      82     118 .. 0.88
   2 !  126.6   0.0   7.3e-40   9.4e-37       1     155 [.     868    1029 ..     868    1032 .. 0.95

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.043
                 HHHHHHHHHHCCCSSEEEEE-TTGG CS
         SKI  49 elEsevlkelleeeglViatGGGav 73 
                 + E  +l++ + ++ ++ia+GGG++
  EEA18560.1  91 DIEDWMLQQTCGRDTVIIALGGGVI 115
                 678889*****************97 PP

  == domain 2  score: 126.6 bits;  conditional E-value: 7.3e-40
                  TTSSHHHHHHHHHHHHTSEEEEHHHHHHHHHTS-HHHHHHHHHHHHHHHHHHHHHHHHCCCS..SEEEEE-TTGGGSHHHHHHHH....HHSEEEEE CS
         SKI    1 mGaGKstvGkllAkklglefiDlDeliekrtgksiaeifeeegeegFrelEsevlkelleee..glViatGGGavlseenrellk....ekgiviyL 91  
                  +GaGK+t+G++ Ak+l+++fiDlD ++e+++gk+i+++++e+g++gFr+ E  ++k+ l+e+  g+V+a+GGG+v+ +e+r++l     +kg v+++
  EEA18560.1  868 RGAGKTTTGRWAAKALNRKFIDLDVELEQTEGKTIPDLIKERGWKGFRDAELSLFKRALTERptGHVFACGGGIVEIAEARNILIdyhkNKGNVLLV 964 
                  7************************************************************99*******************9988988******** PP

                  E--HHHHHHHHHHTTSSGGGCSCHHHHHHHHHHH.HHHHHHCCSSCEEEECTSSHHHHHHHHHHH CS
         SKI   92 dvsleellerlkadkeRPllqekskeeelleela.ereplyeeaadvvvdeseeskeevaeeile 155 
                   +++++++e+l+ dk+RP++ e++ + +l+++ + +++++ + ++ + +  + + +  +++++++
  EEA18560.1  965 MRDIKKVMEFLNIDKTRPAYIEDMMSVWLRRKPWyQECSNVQYYSRHSSSPELALAMDDFDRFIQ 1029
                  ********************************************999988887777777777776 PP

>> Shikimate_dh_N  Shikimate dehydrogenase substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.6   0.0   5.6e-26   7.2e-23       1      83 []    1291    1371 ..    1291    1371 .. 0.99

  Alignments for each domain:
  == domain 1  score: 80.6 bits;  conditional E-value: 5.6e-26
                      EEESS-TT-SHHHHHHHHHHHCTSSEEEEEEE-SCCTHHHHHHHHHHTTESEEEE-TTSCCHHHGGSSEE-HHHHHHT--SEE CS
  Shikimate_dh_N    1 viGnpikhSlSPaihnaafkalglngsyeafeveedelekaveelralglaGlnvTiPfKeaviplldelseeAkaigAvNti 83  
                      ++G+p++ S+SPa+hn++f+++gl+++y+ +e++  + +++ e +r++++ G++ TiP+K ++ipl+de+ +eA+ igAvNti
      EEA18560.1 1291 IFGKPVSVSRSPAMHNTLFEQNGLPYVYTRLETD--QAQDVKEFIRSPDFGGASATIPLKLDIIPLIDEVLNEAEIIGAVNTI 1371
                      79*******************************9..9*********************************************8 PP

>> SDH_C  Shikimate 5'-dehydrogenase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       1.8   2.4e+03      22      31 .]     438     447 ..     438     447 .. 0.89
   2 !   33.3   0.1   2.3e-11     3e-08       1      31 []    1537    1567 ..    1537    1567 .. 0.97

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 1.8
                 -HHHHHHHHH CS
       SDH_C  22 PvevMreall 31 
                 ++evM++al+
  EEA18560.1 438 DTEVMLNALE 447
                 79******95 PP

  == domain 2  score: 33.3 bits;  conditional E-value: 2.3e-11
                  HHHHHHHHHHHHHHHHHS----HHHHHHHHH CS
       SDH_C    1 GLgMLveQgaeqFelWTGrepPvevMreall 31  
                  GL+ Lv+Qg++qFe+WTG++p +ev r+a+l
  EEA18560.1 1537 GLEALVGQGVYQFEYWTGITPVYEVARNAVL 1567
                  9*******************99*******97 PP

>> Fe-ADH_2  Iron-containing alcohol dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.7   0.0   4.8e-11   6.2e-08      11     250 .]      28     288 ..      24     288 .. 0.64

  Alignments for each domain:
  == domain 1  score: 32.7 bits;  conditional E-value: 4.8e-11
    Fe-ADH_2  11 gellkelelkkvllvadentkkaagekveeslkeagikve.....vveeveeead.......leeveklvealreketdlvvavGgGtiiDiakyvsak 97 
                 ++ll++l  ++ +lv+d+n  +++ ek ++ ++ea+  ++     + +e  +  +         ++e+ + +    + ++++a+GgG+i D+  +v+a+
  EEA18560.1  28 QDLLTNLPSTTYVLVTDTNLGSIYREKFAKIFNEAAAALSpaprlLTKEIPPG-EnsksrqgKADIEDWMLQQTCGRDTVIIALGGGVIGDLLGFVAAT 125
                 67888899999999999999999999999999999886554344322222221.12333333334444444444445569**************99865 PP

    Fe-ADH_2  98 ..lnvpyvsvpTaa..SvDGfaspgaslvvdgkkrtvakaaaPlaviaDldvlaeAPrrllasGvGDllgkytaladwklanevse...plaklsaamv 189
                   +++++v vpT++   vD+      ++ +   k  +     P  +++D+d++ + P+r    G+++++ k  a+ d+k   ++++    + k++  + 
  EEA18560.1 126 ymRGIRFVQVPTTLlaMVDSSIGGKTAIDTPLGKNLIGAIWQPHRIYIDIDFIDTLPEREFINGMAEVI-KTAAISDEKEFAALEQhadAILKAARSKP 223
                 3389********953345655555555666544555555678*************************99.77788877766544430003333333333 PP

    Fe-ADH_2 190 qeaaeklvedkketealeellealalsgigisrpa.....SGsEHliSHaldmlalkqalHGeqVG 250
                  +    lv++  ++++++ + ++ a  +++ +r +         H i Ha++++ + q+lHGe V+
  EEA18560.1 224 GKGRFDLVRQVVKDRIVASARHK-AFVVTADEREGglrnlLNLGHSIGHAIEAILSPQVLHGECVA 288
                 33333333333333333222222.23333334444455557778**********99******9885 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0   1.6e-07    0.0002      12      58 ..    1408    1454 ..    1400    1474 .. 0.85

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 1.6e-07
                    T-EEEEES-SHHHHHHHHHHHCCT-CEEEEEESSHHHHHHHHHHHT. CS
  Shikimate_DH   12 ekkvlliGaGemaelvakhLlakgvkkvvvaNRtlerakelaeelkg 58  
                    e+ +l+iG G +a+ ++ +L++ g+  v v++R+ e+ +++a+ + +
    EEA18560.1 1408 ESSALVIGGGGTARAAIYALHNMGFSTVYVLGRSPEKIQNMASTFPT 1454
                    5789***************************************9944 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.0      0.11   1.4e+02      83     143 ..     197     254 ..     137     259 .. 0.63
   2 !    8.8   0.0    0.0015       1.9      25      51 ..     860     886 ..     843     932 .. 0.82
   3 ?   -1.8   0.0       2.8   3.6e+03      58     106 ..    1186    1232 ..    1159    1269 .. 0.71
   4 ?   -0.3   0.1      0.94   1.2e+03       1      35 [.    1382    1419 ..    1382    1425 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.11
      AAA_16  83 rqlldeaesaeleawrekleealaavpelagaea.srllellkrllallsrderplvlvlDd 143
                 +++ de+e a+le++++++++a   +++ +g+++   +++++k+ ++ ++r ++ +v++ D+
  EEA18560.1 197 AAISDEKEFAALEQHADAILKA---ARSKPGKGRfDLVRQVVKDRIVASAR-HKAFVVTADE 254
                 3444556666666666666665...55899999966666666666655555.7779999886 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0015
      AAA_16  25 elvllsGesGvGKsslvrellralekd 51 
                  +++++G++G GK++  r +++al+++
  EEA18560.1 860 ASIVIIGMRGAGKTTTGRWAAKALNRK 886
                 6899************99999999888 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 2.8
      AAA_16   58 gkcdql.esaipysalaqalareellrqlldeaesaeleawrekleeala 106 
                  g + q+  +a+ y  ++++    ++ + l+d+++ +e+ +w+e+ +  + 
  EEA18560.1 1186 GSWIQYyNKALQYGDIIKLV---GVAETLKDNTALREFKDWAEQAHPDVP 1232
                  55555534445554455555...899999999999999999998877665 PP

  == domain 4  score: -0.3 bits;  conditional E-value: 0.94
      AAA_16    1 rlvGReeeleqLlsalervrsgrp...elvllsGesGv 35  
                  rl+GR  +++ + ++l+ + +++    ++ l++G  G+
  EEA18560.1 1382 RLIGRNTDWSGIVRCLREAGAHSNegeSSALVIGGGGT 1419
                  699**************55555555689******9997 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   3.2e-05     0.041       1      82 [.     862     955 ..     862     976 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 3.2e-05
      AAA_18   1 IlltGtpGvGKttlakeLskrlgf.............gvnlrdvakenglllevdpealdeskrldedk.ldklldaleenssaleegknlvidgh 82 
                 I++ G+ G+GKtt ++  +k l+              g  + d++ke+g+   +d+e l+ +kr+ +++ +  ++ +  ++ +  +e+ n++id h
  EEA18560.1 862 IVIIGMRGAGKTTTGRWAAKALNRkfidldveleqteGKTIPDLIKERGWKGFRDAE-LSLFKRALTERpTGHVFACGGGIVE-IAEARNILIDYH 955
                 89****************99996688999*********************9999999.4444444444303333333333333.556666666666 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0    0.0002      0.25       4      42 ..     858     887 ..     855     932 .. 0.79
   2 ?   -3.3   0.0       7.8   9.9e+03      21      57 ..    1216    1248 ..    1215    1258 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.0002
      AAA_22   4 tagilvvtGesGtGKTtllrrlleqldeeakaeeerpev 42 
                 ++ ++v++G  G+GKTt+ r+ ++ l         ++++
  EEA18560.1 858 SDASIVIIGMRGAGKTTTGRWAAKAL---------NRKF 887
                 6789*****************99998.........3333 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 7.8
      AAA_22   21 llrrlleqldeeakaeeerpevvfvtlpsstsskdll 57  
                   lr++++++    ++++++++v+ +++  ++ ++ +l
  EEA18560.1 1216 ALREFKDWA----EQAHPDVPVIAINMGDKGQLSRML 1248
                  566777776....556689999999988887666555 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0       7.7   9.9e+03      14      50 ..     149     187 ..     149     206 .. 0.69
   2 ?   11.6   0.0   0.00017      0.22       4      54 ..     861     904 ..     858     921 .. 0.79

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 7.7
      AAA_14  14 GKTtllkqlikell..vkkesilyinldderdkkladpe 50 
                 GKT +   l k+l+  + + + +yi++d  ++  ++++ 
  EEA18560.1 149 GKTAIDTPLGKNLIgaIWQPHRIYIDIDFIDTLPEREFI 187
                 888888888888888888888999999988887666553 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 0.00017
      AAA_14   4 ilvitGaRrvGKTtllkqlikellvkkesilyinldderdkkladpeklle 54 
                  +vi G+R +GKTt  +  +k l    ++++ ++++ e+++ ++ p    +
  EEA18560.1 861 SIVIIGMRGAGKTTTGRWAAKALN---RKFIDLDVELEQTEGKTIP----D 904
                 589************888887766...9999999998888766655....3 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0       7.5   9.6e+03     150     173 ..     198     221 ..     184     244 .. 0.75
   2 ?   11.9   0.0    0.0001      0.13       3      55 ..     860     917 ..     858     956 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 7.5
      AAA_24 150 pklgkktanelkeevDlvlranlk 173
                    ++k +++l++++D +l a  +
  EEA18560.1 198 AISDEKEFAALEQHADAILKAARS 221
                 556778899999999999988765 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 0.0001
      AAA_24   3 lkiliyGpsgiGKTtlakel..gpkplfidtekGlksldadkfpdie...swedflde 55 
                 ++i+i+G  g+GKTt+ + +    +  fid++  l +++++ +pd+    +w+ f+d+
  EEA18560.1 860 ASIVIIGMRGAGKTTTGRWAakALNRKFIDLDVELEQTEGKTIPDLIkerGWKGFRDA 917
                 789************9888855456669999999999999999998889999999986 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0       2.7   3.5e+03      83     104 ..    1133    1154 ..    1131    1172 .. 0.68
   2 ?   11.3   0.0   0.00024       0.3       2      59 ..    1412    1470 ..    1411    1480 .. 0.80

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 2.7
                       HHHHHHHHHHT-EEEESS-BCG CS
  Sacchrp_dh_NADP   83 ldvlkaCietgvhyvdtsiske 104 
                       l+++ ++i+ g+ ++d +i+ +
       EEA18560.1 1133 LELIMLAIRSGCEFIDLEITFP 1154
                       678999**********888322 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00024
                       EEE--SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHH...TTTCEEEEE--TTTH CS
  Sacchrp_dh_NADP    2 liiGaGsvGqavaellarhfdvdaeitvadrskeklealaaka...lgvrfeaialdaeny 59  
                       l+iG+G++++a++  l++ +    ++ v +rs ek +++a++      +r+   a d+en+
       EEA18560.1 1412 LVIGGGGTARAAIYALHNMGFS--TVYVLGRSPEKIQNMASTFptgFDIRVLENASDIENI 1470
                       89****************9977..9**************9876655555555555566655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1573 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       468  (0.026103); expected 358.6 (0.02)
Passed bias filter:                      450  (0.025099); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.93u 0.29s 00:00:01.22 Elapsed: 00:00:00.44
# Mc/sec: 10659.11
//
Query:       EEA18561.1  [L=591]
Description: hypothetical protein PMAA_008400 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.2e-58  197.0   0.3      1e-57  196.1   0.3    1.5  1  DDE_Tnp_1_7      Transposase IS4
    6.8e-12   46.0   9.4    1.5e-11   44.9   9.4    1.7  1  Tnp_zf-ribbon_2  DDE_Tnp_1-like zinc-ribbon


Domain annotation for each model (and alignments):
>> DDE_Tnp_1_7  Transposase IS4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  196.1   0.3   1.1e-61     1e-57       2     350 .]      69     482 ..      68     482 .. 0.90

  Alignments for each domain:
  == domain 1  score: 196.1 bits;  conditional E-value: 1.1e-61
  DDE_Tnp_1_7   2 pvelFelflpdkilerivkatNayakqk.........kkwleltaeElkaFlGllllmglvrlpsvedyWstkdfyg....npllseiMsreRFeeil 86 
                  p+++F+lf+++++++ +++ tN+ya  k         ++w+ +t  ElkaF+G+++ mg  + p+++dyW+++++ +    n++ls +++  RFe++ 
   EEA18561.1  69 PYQIFSLFFTEDLFKVLADNTNMYAYAKlsknmnphhRNWRSTTPGELKAFVGAQIYMGFTKEPQLKDYWDEEKHNKsvhaNHPLSNYITCFRFEQLK 166
                  9**********************************************************************9995555678***************** PP

  DDE_Tnp_1_7  87 salhladn........................stkkaekdklkkvrelidslnermqkvyrpsqtlvldeslvlfkgrvpfkqylpgkprkvgiklhv 160
                  + +h++++                        s+++ +    +kv  ++d l +  +++y ps+++++de +v  +gr +    +p+kp   g+k++v
   EEA18561.1 167 RFFHISEPsevpggfistyyrpepteeeelqlSEEQLSGIWWHKVHTVFDILRKASKNLYIPSSNISIDEAMVCSHGRSSHTYKMPNKPISQGFKIFV 264
                  ***********************9999888664444488999******************************************************** PP

  DDE_Tnp_1_7 161 lcdsqtgyilalelyegearnlrl..srelgktnalvlrLleplqgkg..rvvvmdnfftslellqeLakkgtyavGtlkknrsglPkeltqklpkge 254
                  l+d   gy + +++  ++++ ++    +el+kt ++v +L+++l + +  + +++dn+fts++l+++L++ ++ a+Gt +  ++++P+ l++ ++ g+
   EEA18561.1 265 LAD--HGYCYYFYPASRTKGVVEVgmAKELTKTGQMVYELVQTLPKDNktYDLYLDNYFTSVNLFKALREIQVGACGTTRP-HKEFPNLLKKLKDLGS 359
                  ***..9**********999877653378****************965555*******************************.77***88876666666 PP

  DDE_Tnp_1_7 255 llaryg......gplmllkwndrkkvkllstyss....qklveskersg................qki..karpklvedYnqalgavdrhdqllqayr 324
                     +++      +++  ++w d++ v+ l+t+++    ++ +e+ +r+                 q +     p  ++dYn ++g+vd ++q ++ y 
   EEA18561.1 360 YIPYHKvcaipvNDVLCVAWQDNNIVLALTTIHTvdqtDDYIERTRRRPqktstngplvhkefgeQAVknMPIPRFIDDYNSHMGGVDIANQHRAVYD 457
                  666666666666**********************876555588777775677888899999998844543479************************* PP

  DDE_Tnp_1_7 325 aslktskkwykrvlifllsiavvNAy 350
                   ++k+ ++w+  +   +l++ +vNAy
   EEA18561.1 458 THIKAFRSWWP-LWNWCLDVGIVNAY 482
                  **********9.*************9 PP

>> Tnp_zf-ribbon_2  DDE_Tnp_1-like zinc-ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.9   9.4   1.7e-15   1.5e-11       1      31 []     543     584 ..     543     591 .] 0.94

  Alignments for each domain:
  == domain 1  score: 44.9 bits;  conditional E-value: 1.7e-15
  Tnp_zf-ribbon_2   1 kRCkvClkkkikke.......TriiCqeCdvplCrnh....C 31 
                      kRC++Cl+k++k++       T++iCq+CdvplCr++    C
       EEA18561.1 543 KRCIWCLYKNPKRQtgqspsfTTFICQACDVPLCRPEtgrtC 584
                      8**********************************9877776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (591 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       530  (0.029561); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.45
# Mc/sec: 3933.08
//
Query:       EEA18562.1  [L=140]
Description: hypothetical protein PMAA_008410 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (140 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       288  (0.0160634); expected 358.6 (0.02)
Passed bias filter:                      232  (0.0129399); expected 358.6 (0.02)
Passed Vit filter:                         8  (0.000446204); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.41u 0.28s 00:00:00.69 Elapsed: 00:00:00.44
# Mc/sec: 966.47
//
Query:       EEA18563.1  [L=375]
Description: hypothetical protein PMAA_008420 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00022   21.1   0.8    0.00048   20.0   0.1    1.9  2  F-box_4   F-box
     0.0061   16.4   2.3       0.02   14.8   0.2    3.0  3  F-box     F-box domain


Domain annotation for each model (and alignments):
>> F-box_4  F-box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   0.1   5.3e-08   0.00048       4      43 ..       9      48 ..       7      61 .. 0.93
   2 ?   -3.0   0.1       0.7   6.3e+03      28      48 ..     261     283 ..     254     289 .. 0.63

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 5.3e-08
     F-box_4  4 sLssLPlevlqhiaslLDsfsLsqLslvskllrevcssll 43
                +L++LP+ev+q ia++L    + ++s v+k+lr+vc   l
  EEA18563.1  9 TLNRLPIEVIQAIATMLPLPHMKEFSCVNKKLRNVCLPFL 48
                689*********************************7655 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.7
     F-box_4  28 Lslvskllr..evcssllqergi 48 
                 Ls+   ++r  ++c+  l+er +
  EEA18563.1 261 LSRCVLKIRqlDMCTLHLHERDV 283
                 45555555522568888888765 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.2   2.3e-06      0.02       2      37 ..       9      44 ..       8      48 .. 0.96
   2 ?   -2.3   0.0       0.5   4.5e+03      30      39 ..      69      78 ..      68      80 .. 0.85
   3 ?   -1.4   0.0      0.26   2.3e+03       6      15 ..     321     330 ..     312     331 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 2.3e-06
                HHHHS-HHHHHHHHHTS-HHHHHHHCTT-HHHHHHH CS
       F-box  2 tlsrLPsevlrhILerLplsdllalrrVSkgwrili 37
                tl rLP ev+  I   Lpl +   +++V k++r+++
  EEA18563.1  9 TLNRLPIEVIQAIATMLPLPHMKEFSCVNKKLRNVC 44
                789*******************************98 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 0.5
                -HHHHHHHTT CS
       F-box 30 Skgwrilids 39
                S g+r +++s
  EEA18563.1 69 SSGLRHCVKS 78
                8899*99997 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.26
                 S-HHHHHHHH CS
       F-box   6 LPsevlrhIL 15 
                 L +++l++IL
  EEA18563.1 321 LTPDLLCNIL 330
                 6688*****9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (375 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       505  (0.0281667); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.23s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2689.85
//
Query:       EEA18564.1  [L=357]
Description: DUF636 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.1e-13   48.9  14.3    2.6e-08   34.1   2.8    2.7  3  GFA       Glutathione-dependent formaldehyde-activating enzym


Domain annotation for each model (and alignments):
>> GFA  Glutathione-dependent formaldehyde-activating enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.1   2.8   1.5e-12   2.6e-08       2      92 ..      35     129 ..      34     130 .. 0.81
   2 ?   -3.7   0.6      0.89   1.6e+04       2       5 ..     180     183 ..     179     185 .. 0.81
   3 !   23.6   0.1   2.7e-09   4.8e-05       4      80 ..     221     304 ..     218     324 .. 0.72

  Alignments for each domain:
  == domain 1  score: 34.1 bits;  conditional E-value: 1.5e-12
         GFA   2 lChCsdCrkasgsaftanavvkae.alelleg....elkeykktadsgnkvtrsfCpeCgsplyseesaapevvivrvGtlddp..eklkpeaeiftk 92 
                  ChCs Cr  +g++f +++++++  + ++++     +++ y+     g++ t  fC++Cg+++ ++   ++++++v   ++ ++  ++++ +++ f k
  EEA18564.1  35 FCHCSLCRYVTGAPFIVHTTLPSGvKPRFIAPssehNITNYA---PAGSECTLGFCSTCGCHINARDPMDSNFYVVSSSIFSEQraDCFHIKLHAFSK 129
                 5****************9999865323333332234566666...69******************9999999*********99988999999999876 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 0.89
         GFA   2 lChC 5  
                 +ChC
  EEA18564.1 180 QCHC 183
                 8*** PP

  == domain 3  score: 23.6 bits;  conditional E-value: 2.7e-09
         GFA   4 hCsdCrkasgsaftanavvkaeale......llegelkeykktadsgnkvtrsfCpeCgsplyseesaape.....vvivrvGtlddp 80 
                  C+dCr  +g+ +   ++++ +  e      l  g++k+y     s+ +v rsfC +Cg++++++ + ++      vv +++G++  p
  EEA18564.1 221 ICDDCRLVTGTHVIGWTFIPLQCCEpvieadLKIGTAKTYV----SSVGVLRSFCGTCGATVFYSHEDRQRgdgrqVVDLATGIIRAP 304
                 6******************9998886333333344556665....899***************9844333335666888888888777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (357 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       464  (0.0258799); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2539.74
//
Query:       EEA18565.1  [L=1042]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.1e-38  132.3   0.2    3.5e-38  131.6   0.2    1.3  1  RVT_2         Reverse transcriptase (RNA-dependent DNA polyme
  ------ inclusion threshold ------
      0.017   14.7   0.0      0.033   13.7   0.0    1.4  1  RVT_1         Reverse transcriptase (RNA-dependent DNA polyme
      0.053   13.8   2.8       0.15   12.4   2.8    1.8  1  Orthopox_F14  Orthopoxvirus F14 protein
      0.054   13.4   0.0       0.12   12.2   0.0    1.6  1  Flg_hook      Flagellar hook-length control protein FliK


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  131.6   0.2   7.8e-42   3.5e-38       9     234 ..     554     776 ..     545     782 .. 0.91

  Alignments for each domain:
  == domain 1  score: 131.6 bits;  conditional E-value: 7.8e-42
       RVT_2   9 PkdrkaigsrWvftkkkddl.kevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeeelvvhqldvdsafLnaeldeevyvkqPpGfeid 106
                  k+++ +   W++  k+d++ + vk karlv++G  q    d  +++a  +   s r ++a+aa  +l + q d   af+na+ldee++++  pG+   
  EEA18565.1 554 AKGKQILDCMWIYVYKQDKKgRLVKCKARLVVRG-DQEKRDDMRDTYAATLAARSFRTFMAIAARFDLELKQYDAVNAFVNAKLDEEIFMRMAPGYR-- 649
                 577888999********999899***********.577889******************************************************96.. PP

       RVT_2 107 reeekvykLnkslyGlkqapllWnekidkvLkklgferseaesGlyvrgtgegklivalyvddlliagsdikil..edvkkelakkfklkdlgkvskfL 203
                  e++k+y+Lnk+lyGl+++pllW+++++++L klgf+  + e    +++     +++  yvdd+++a ++++ l  + + ++l +k++++   +++ fL
  EEA18565.1 650 -ESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFRAVPHEPCCMLKS----GVMLFFYVDDIVVAYKKSRQLeaNSILNQLRAKYNISGGEDLEWFL 743
                 .46****************************************999999....78999*********9999877225799******************* PP

       RVT_2 204 Gieiaq..eaggiklsladyiakvvkkfeltda 234
                 G+ i++  ++  i ls+a yi k++k ++ ++a
  EEA18565.1 744 GMRIIRdrSNKMIWLSQATYIDKIAKLADTQQA 776
                 ****986568889***********998876655 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   7.4e-06     0.033     117     185 ..     643     725 ..     614     735 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 7.4e-06
                 .........TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T................TEEECTTEEEEEESSHHH..HHHHHH CS
       RVT_1 117 rv.nge.eskgryekkglpqGsvlSPllfnlfmnellrelrkra..........kgvtllrYaDDililskskee..lqelle 185
                 r+  g  es+++y+ +    G+  SPll++  +++ l +l  ra          +gv l  Y+DDi++++k+  +  ++++l+
  EEA18565.1 643 RMaPGYrESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFRAvphepccmlkSGVMLFFYVDDIVVAYKKSRQleANSILN 725
                 4434444789999999999****************9999999999***************************88844444454 PP

>> Orthopox_F14  Orthopoxvirus F14 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   2.8   3.3e-05      0.15      32      70 ..     246     283 ..     234     286 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 3.3e-05
  Orthopox_F14  32 idedditellniltelGcdvdfdedfsdiaddvleslie 70 
                   +  ++it ll  l +lG d dfd++++d+ d + + +++
    EEA18565.1 246 VSTQEITRLLTKL-DLGTDADFDDEYADLIDHITDVVFD 283
                   5667888888776.79***************99887765 PP

>> Flg_hook  Flagellar hook-length control protein FliK
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   2.7e-05      0.12      34      69 ..     928     963 ..     920     979 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2.7e-05
                 ETTEEEEEEEE-SCHHHHHHHHTHHHHHHHHHCCTT CS
    Flg_hook  34 rggqlsvqltaenpetrelLeqnlprLreaLaaaGl 69 
                 r +  ++++  +n++t+ lLe+++prLr+ L+   +
  EEA18565.1 928 RFQTPTLHVYCDNQQTLGLLEKDAPRLRTKLRHVDI 963
                 55566899***********************87544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1042 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       534  (0.0297841); expected 358.6 (0.02)
Passed bias filter:                      479  (0.0267165); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.74u 0.28s 00:00:01.02 Elapsed: 00:00:00.45
# Mc/sec: 7020.54
//
Query:       EEA18566.1  [L=661]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      1e-05   25.3   1.3    2.5e-05   24.0   0.1    2.1  2  gag_pre-integrs  GAG-pre-integrase domain
  ------ inclusion threshold ------
       0.27   11.7   4.0        6.3    7.3   0.3    2.6  2  REV1_C           DNA repair protein REV1 C-terminal domain
        4.7    7.0   5.8          1    9.1   0.2    2.5  3  Sulfotransfer_4  Sulfotransferase domain


Domain annotation for each model (and alignments):
>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.1      0.35   2.1e+03      56      63 ..     360     367 ..     345     367 .. 0.74
   2 !   24.0   0.1   4.2e-09   2.5e-05      19      44 ..     614     639 ..     596     652 .. 0.83

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.35
  gag_pre-integrs  56 sevCeaCq 63 
                       +vCeaC+
       EEA18566.1 360 RPVCEACE 367
                      569****6 PP

  == domain 2  score: 24.0 bits;  conditional E-value: 4.2e-09
  gag_pre-integrs  19 knkssinlWHrRLGHpsfsrlkkLfk 44 
                        k ++n+WH RLGHp+ + lk+L+ 
       EEA18566.1 614 ERKADANRWHARLGHPGPEVLKHLAG 639
                      35899*******************85 PP

>> REV1_C  DNA repair protein REV1 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.3    0.0063        37      44      82 ..     148     186 ..     128     188 .. 0.84
   2 ?    7.3   0.3    0.0011       6.3      17      81 ..     207     269 ..     199     277 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0063
      REV1_C  44 vavlkwlrvlleeeeeskeeeageaWekafrevkeavqe 82 
                 +++  w+++ +  + +++   ++ +W++a+ ++ke+v++
  EEA18566.1 148 EQIFIWMKQTVSPSYHKTCIAVTANWKEAYINLKEQVNQ 186
                 5677799999998888999999***************96 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0011
      REV1_C  17 gPneeDvealakyLkkvv..eeerdlekavavlkwlrvlleeeeeskeeeageaWekafre.vkeavq 81 
                 +P  +D+ea  +  ++++  +e + +  a +vl w  + l+       +  ++aW +a++  ++e+++
  EEA18566.1 207 KPSTRDLEAWITKWEELLleAERKSMVIADDVLDWSTRFLDAI-----RPLDDAWTTAYEItIEEKIE 269
                 7999*****99999999988888********************.....9*********9853666665 PP

>> Sulfotransfer_4  Sulfotransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.3      0.17     1e+03     130     172 ..     144     185 ..     123     207 .. 0.53
   2 ?    9.1   0.2   0.00017         1      97     175 ..     210     293 ..     208     299 .. 0.77
   3 ?   -2.8   0.0      0.79   4.7e+03     143     174 ..     378     411 ..     354     440 .. 0.64

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.17
  Sulfotransfer_4 130 lellaklvellralvrrlfgagsdaedeeaakeayeehnervr 172
                      +++ ++++ +++++v+  ++++    +++++keay + +e+v 
       EEA18566.1 144 KKAIEQIFIWMKQTVSPSYHKT-CIAVTANWKEAYINLKEQVN 185
                      3444555555555555555553.33555555555555555554 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.00017
  Sulfotransfer_4  97 eRdpekWlksmkktllalrsetls...rllalldpllellaklvellralvrrlfgag.s.daedeeaakeayeehnervrevv 175
                      +Rd e+W ++++++ll++ ++ +     +l + +++l++ ++l +++ ++++  ++++    + +++++++a+++  +++r+  
       EEA18566.1 210 TRDLEAWITKWEELLLEAERKSMViadDVLDWSTRFLDAIRPLDDAWTTAYEITIEEKiEdGTLTRRELANAFRRNLRKIRNRR 293
                      8**************999988554344788888889999999999999999998888754234566777777777777777655 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 0.79
  Sulfotransfer_4 143 lvrrlfgag.s.daedeeaakeayeehnervrev 174
                      l+++l  ++   ++  + +ak++ e+h + v+++
       EEA18566.1 378 LFKNLAPEEfIpRWGPRMRAKKFAEDHPDLVKKI 411
                      3333333332234566667777777777777664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (661 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       953  (0.0531541); expected 358.6 (0.02)
Passed bias filter:                      610  (0.0340231); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.66u 0.27s 00:00:00.93 Elapsed: 00:00:00.43
# Mc/sec: 4566.79
//
Query:       EEA18567.1  [L=717]
Description: DNA helicase recq, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.1e-13   50.6   0.0    4.2e-13   49.6   0.0    1.5  1  Helicase_C     Helicase conserved C-terminal domain
    3.5e-11   43.2   1.1    3.8e-05   23.5   0.0    2.4  2  DEAD           DEAD/DEAH box helicase
    0.00024   21.1   0.2       0.42   10.6   0.0    2.7  3  ResIII         Type III restriction enzyme, res subunit
  ------ inclusion threshold ------
      0.016   14.5   0.0      0.029   13.6   0.0    1.3  1  ERCC3_RAD25_C  ERCC3/RAD25/XPB C-terminal helicase
      0.051   13.8   1.8       0.71   10.1   0.0    2.8  2  CTU2           Cytoplasmic tRNA 2-thiolation protein 2
      0.078   12.8   0.0       0.17   11.7   0.0    1.5  1  TK             Thymidine kinase
        1.9    6.5  25.5        2.5    6.1  25.5    1.0  1  AF-4           AF-4 proto-oncoprotein


Domain annotation for each model (and alignments):
>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.6   0.0   1.6e-16   4.2e-13      12     110 ..     206     297 ..     196     298 .. 0.89

  Alignments for each domain:
  == domain 1  score: 49.6 bits;  conditional E-value: 1.6e-16
                 HTTTTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSSHHHHHHHHTTSSST CS
  Helicase_C  12 leeeggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprnvtsyiqriGRtgRa 110
                 ++ ++gk++i++nti +++    +   +++++ ++++  ++ +++ +l++f+k++  v++at+++++Gidip+++lVi+++  r++ +y q +GR+gR 
  EEA18567.1 206 QQLHEGKVVIYANTIATVQ---RI--AHQLQCPAYYS--QAVDKKGMLASFQKQNPGVIVATSALGMGIDIPDIRLVIHVGRTRSLLDYGQESGRAGRD 297
                 56689*************5...55..46689999999..89999*******887777*****************************************6 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.2     6e-07    0.0015       3      56 ..      20      67 ..      18      70 .. 0.83
   2 !   23.5   0.0   1.5e-08   3.8e-05      96     174 ..      74     151 ..      68     153 .. 0.72

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 6e-07
                HHHHHHHHHHTTC.EEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESS CS
                xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  3 iQaeaiplilggg.dvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePt 56
                 Q+++i+ i++ +  +++ ++TG+GK+l f++p+         ++g  +++v+P+
  EEA18567.1 20 TQKAVIQSIVQRQsPIVAIMPTGAGKSLLFMLPAW-------MSRGGTTIVVVPL 67
                599*******766378899***************9.......3556677888886 PP

  == domain 2  score: 23.5 bits;  conditional E-value: 1.5e-08
                 TTCSEEEEEHHHHHHHH.....HCTSSHCTTEEEEEEETHHHHHHT..TTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHHH CS
                 xxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  96 ngvdivvgtpgrlddll.....stgklnlsqvrflVlDEadrlldq..gfsdfinrilnqlpqitcdgklqrqvivlSATlpkdvk 174
                  g+ iv+ tp+  ++ +     + +k  ++++  +V+DE++ +l++  +f++++ ++ +         +++ q+++l+ATlp++ +
  EEA18567.1  74 DGAAIVLVTPESAMSETfqtfiN-RKQWTKELDRIVIDECHIILQEgyQFRKQMAQLGAL-------VRAETQLVLLTATLPRESE 151
                 5789******9999966465533.3435999***************44444555553333.......345567*********8765 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.6   0.0   0.00016      0.42       7      47 ..      20      55 ..      14      69 .. 0.73
   2 !    7.5   0.0    0.0014       3.6     105     170 ..      77     147 ..      68     148 .. 0.64
   3 ?   -2.1   0.0       1.3   3.2e+03      41      75 ..     197     231 ..     195     257 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00016
                HHHHHHHHHT......TTSEEEEEESTTSTHHHHHHHHHHH CS
      ResIII  7 yQeeaienlleklkskrdkrglikmaTGtGKTlvaaklier 47
                 Q+ +i++++     +r+  ++  m+TG+GK+l+ +  ++ 
  EEA18567.1 20 TQKAVIQSIV-----QRQSPIVAIMPTGAGKSLLFMLPAWM 55
                5555555555.....8999*************998776665 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0014
                 SEEEEEHHHHHHTH........HHHTTT-SEEEEETGGGTTS......TTTHHHHHT-.--SEEEEEESS-S CS
      ResIII 105 kilvttiqsldadseeeeeeseellrdrfdviiiDEaHrlgak.....kswreilekf.keavllglTATpe 170
                  i+++t +s+ ++   ++  + ++  ++ d i+iDE+H + ++     k++ ++   +  e  l+ lTAT++
  EEA18567.1  77 AIVLVTPESAMSET-FQTFINRKQWTKELDRIVIDECHIILQEgyqfrKQMAQLGALVrAETQLVLLTATLP 147
                 56666666666666.3344455555666779*******9999655555566666333324477778899986 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 1.3
                 HHHHHHHH-S.....-EEEEESSHHHHHHHHHHGG CS
      ResIII  41 aaklierllkkgkeekflflvprkslleqtleefk 75 
                 ++  i++  ++ +e k+++ +++++ +++  ++++
  EEA18567.1 197 MITWIQQRVQQLHEGKVVIYANTIATVQRIAHQLQ 231
                 67778888888888899999999988888776665 PP

>> ERCC3_RAD25_C  ERCC3/RAD25/XPB C-terminal helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.0   1.1e-05     0.029      58     147 ..     203     296 ..     190     302 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 1.1e-05
  ERCC3_RAD25_C  58 kr.....gDkiivfsDnvfaLkeyakklkkpyiyGetseaerlkilqkfkknpkvntiflskvgDtsiDlPeanvliqisshfg..srrqeaqrlG 146
                    +r     + k++++++ + +++++a++l+ p  y ++   +++ +l +f+k++    +  s +g   iD+P+   +i +    +     qe+ r G
     EEA18567.1 203 QRvqqlhEGKVVIYANTIATVQRIAHQLQCPAYYSQA--VDKKGMLASFQKQNPGVIVATSALG-MGIDIPDIRLVIHVGRTRSllDYGQESGRAG 295
                    444444488**********************999765..566789*******999999999999.68**********9976543113456666666 PP

  ERCC3_RAD25_C 147 r 147
                    r
     EEA18567.1 296 R 296
                    5 PP

>> CTU2  Cytoplasmic tRNA 2-thiolation protein 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   0.00028      0.71      17      97 ..     216     409 ..     201     423 .. 0.80
   2 ?    1.5   0.4      0.13   3.4e+02      45      72 ..     552     578 ..     524     614 .. 0.56

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00028
        CTU2  17 fpstvstvvrTgeKLvknksseeae.......................................................................... 41 
                 +++t++tv r ++ L+ +   ++a                                                                           
  EEA18567.1 216 YANTIATVQRIAHQLQCPAYYSQAVdkkgmlasfqkqnpgvivatsalgmgidipdirlvihvgrtrslldygqesgragrdgaasqaimlidghgagw 314
                 788999999999999988876555588889999999999999999999999999999999999999999999999999999999999999999999999 PP

        CTU2  42 .......................................letsekCalCglplddkakewkrtitiselseteseeekeelekakeeeeeeaeee 97 
                                                         + ++ C  C++++d+++++ +++ ++  ++++++++e + + + +++++++ + +
  EEA18567.1 315 gdpptvdsrvqeylgggcrrraldiylggtvdgytrqqcEDGEAICDQCQSSIDPNPASPNASPNGWLSARQNNRQEASDSASDSASDSASDSAS 409
                 999999999999999999999999999999999999997778899*************9888877777777777777555544444444433333 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.13
        CTU2  45 sekCalCglplddkakewkrtitisels 72 
                 + +C lCg++  + a++   +    + +
  EEA18567.1 552 AGQCRLCGMTG-QPAHHRIGNCPHPQAQ 578
                 57899999998.4444443333333333 PP

>> TK  Thymidine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   6.7e-05      0.17      62     107 ..      90     133 ..      34     137 .. 0.59

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 6.7e-05
          TK  62 ktssleeikeeleeedvdvvlvDEaqFfeqdivelseklanegkiv 107
                   +++  i++++ ++++d +++DE++ + q+ +++ +++a+ g  v
  EEA18567.1  90 TFQTF--INRKQWTKELDRIVIDECHIILQEGYQFRKQMAQLGALV 133
                 23333..344444456999**********************99766 PP

>> AF-4  AF-4 proto-oncoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1  25.5   0.00099       2.5     436     613 ..     354     530 ..     349     553 .. 0.53

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.00099
        AF-4 436 sdeeqapekpksssapssa.pqstpes..vesahsssaeSeSsSeSeSSSeSDSesEssssdseanepprtatpepeppatnkWqLdnwlnkvnqlass 531
                 +d e  +++++ss +p  a p+++p+   ++  ++++++S S S+S S S SDS s+s  sds+   ++ +   +p + ++ +   d      +++as 
  EEA18567.1 354 EDGEAICDQCQSSIDPNPAsPNASPNGwlSARQNNRQEASDSASDSASDSASDSASDS-ASDSASDSASDPGR-DPASDSASDPARDPASDPASHPASH 450
                 5667778888887766543044444445544444555555555555555555555555.55665554444333.4444444444444444444455555 PP

        AF-4 532 qeessaessseteesespkkeskeqsqgkskssssevvees.seskpkakskaeqkkseekqdkrskqkspaqkeseepntrk 613
                 + + ++ s+s+++++ + +++++  +++ ++++s++++ ++ s+   k+  ++++ ++ +k  +r +   p++   + p +r+
  EEA18567.1 451 PAS-HSASHSAIHDRPNGCPNNRPRTSHFTSPNSHHIAIPTpSPGPRKRAISHHSIPPMAK--RRAHPIFPSTAYYQGPMQRQ 530
                 555.557777777776666777777777777777666655413333344444444444444..33333344444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (717 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       866  (0.0483016); expected 358.6 (0.02)
Passed bias filter:                      515  (0.0287244); expected 358.6 (0.02)
Passed Vit filter:                        80  (0.00446204); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.76u 0.28s 00:00:01.04 Elapsed: 00:00:00.44
# Mc/sec: 4859.52
//
Query:       EEA18568.1  [L=952]
Description: hypothetical protein PMAA_008560 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.9e-20   71.2   0.0    2.4e-19   69.9   0.0    1.8  1  OrsD      Orsellinic acid/F9775 biosynthesis cluster protein 


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.9   0.0   1.3e-23   2.4e-19       3     114 .]      12     119 ..      10     119 .. 0.93

  Alignments for each domain:
  == domain 1  score: 69.9 bits;  conditional E-value: 1.3e-23
        OrsD   3 feyneeyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgLpvy.eGyrC.rakakCkylt 99 
                 fe+  ++ v+iCreC+y+v+ps++e HL++ h+ ++   + +l  +v      r + e+a ++ ++++p+  s+ ip+L    +G +C   + +C y++
  EEA18568.1  12 FERLVDFPVVICRECQYGVWPSQIEGHLQHAHHYISPVIRIQLGDEV------RGWPEIAIDPIELDIPPIRSQAIPQLIGPlDGWQCqLSPGSCLYVC 104
                 78888999*********************999999888888888988......*************************98766*****778889***** PP

        OrsD 100 rslktlrkHlqkkhg 114
                  s++t+r+H+ k+hg
  EEA18568.1 105 PSISTMRQHWFKQHG 119
                 ***********9995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (952 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       597  (0.033298); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.71u 0.29s 00:00:01.00 Elapsed: 00:00:00.47
# Mc/sec: 6063.07
//
Query:       EEA18569.1  [L=210]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.9e-17   62.8   0.0    7.8e-17   61.8   0.0    1.4  2  HsbA      Hydrophobic surface binding protein A


Domain annotation for each model (and alignments):
>> HsbA  Hydrophobic surface binding protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.8   0.0   4.3e-21   7.8e-17       7     119 ..      39     151 ..      35     152 .. 0.96
   2 ?   -3.3   0.0      0.63   1.1e+04      22      40 ..     178     197 ..     174     200 .. 0.58

  Alignments for each domain:
  == domain 1  score: 61.8 bits;  conditional E-value: 4.3e-21
                 HHHHHHHHHHHHHHHHHH--SH..HHHHHHHHHHHHHHHHHHHHHHHTS----HHHHHHHHHHHH.HCHHHHHHHHHHHHHTHHHHHHHT-HHHHHHHH CS
        HsbA   7 dittistavtaldtavnafnGgasalpilsasnalvsaikkattdaqasapltdeealalaqavq.tLepdvkaaldaliaKkpafdkagltslvlssL 104
                 +i+ i + +++l+ ++ +++Gg +   +l ++  + ++i++++  ++++++l+d+e+  ++++vq ++e+ +  a++ali+K++ + +ag++s +l+sL
  EEA18569.1  39 VISGIRDLLDQLNLDIHNYTGG-DPSYLLADFERIMHTINQGIPIIRSQPSLDDNETGLFIHYVQiKFEDPIRWAIEALIKKRDSLVTAGFGSPILQSL 136
                 68999999*************5.79************************************************************************** PP

                 HHHHHHHHHHHHHHH CS
        HsbA 105 qdlkaasdaLsdalv 119
                 q+l  a ++L d++ 
  EEA18569.1 137 QRLEVAFEDLRDTVS 151
                 ***********9985 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 0.63
                 HHH--SH...HHHHHHHHHH CS
        HsbA  22 vnafnGg.asalpilsasna 40 
                 ++af G   + + + +as++
  EEA18569.1 178 ITAFAGPiPTSTGVSTASTT 197
                 56666633445666666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (210 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       554  (0.0308997); expected 358.6 (0.02)
Passed bias filter:                      520  (0.0290033); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.27s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1527.00
//
Query:       EEA18570.1  [L=648]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.3e-07   29.4   0.0    1.2e-06   28.3   0.0    1.6  1  gag_pre-integrs  GAG-pre-integrase domain
    1.4e-05   25.3   0.2    3.2e-05   24.1   0.2    1.6  1  rve              Integrase core domain
  ------ inclusion threshold ------
      0.078   13.6   0.0       0.89   10.2   0.0    2.4  2  QIL1             MICOS complex subunit MIC13, QIL1
       0.12   12.5   0.1       0.26   11.4   0.1    1.5  1  GXWXG            GXWXG protein


Domain annotation for each model (and alignments):
>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.3   0.0   2.7e-10   1.2e-06      20      66 ..     478     528 ..     462     529 .. 0.79

  Alignments for each domain:
  == domain 1  score: 28.3 bits;  conditional E-value: 2.7e-10
  gag_pre-integrs  20 nkssinlWHrRLGHpsfsrlkkLfkkgl...lpglkisk.sevCeaCqlgK 66 
                       k  +++WH RLGHp+ + ++ L+  g    l gl+++    +CeaC+ +K
       EEA18570.1 478 RKANAERWHARLGHPGPQIIEYLAGAGRgvrLTGLSKGPtTVECEACASSK 528
                      478899******************8666556777776543559*****998 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.2   7.1e-09   3.2e-05       2     100 ..     542     645 ..     541     647 .. 0.87

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 7.1e-09
         rve   2 trpgelwqvDvt...vvripdggg...kayllvvvddfsrlilaealsdemdastvlalleravarfggve...pervlsDngseytskafrefladlg 91 
                 +rpge++  D+    +  ++       k  l+ ++d++s++++ ++l+ + ++  +l++l+ ++++++++    p ++ +Dn  + +  ++++++++ +
  EEA18570.1 542 ERPGEHLALDFHdfeKSTLK---NdkdKRTLILITDCYSGFMWDFYLTGH-TTVEILETLKWFFQYLKKRYnmtPVKIEMDNEITHRHLEVKDWIKQQH 636
                 68999999999954323333...2345***********************.9999******9999999988************999988********** PP

         rve  92 irvsftrpg 100
                 ++++++ ++
  EEA18570.1 637 VTIKTSVAY 645
                 ***999776 PP

>> QIL1  MICOS complex subunit MIC13, QIL1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.0      0.28   1.3e+03      15      38 ..     122     145 ..     119     171 .. 0.81
   2 ?   10.2   0.0    0.0002      0.89       3      39 ..     414     450 ..     412     465 .. 0.87

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.28
        QIL1  15 elykkakeyipPyvdevkkklcle 38 
                 ++y+++k+ +  ++ +++kk+  e
  EEA18570.1 122 QAYQNLKAHVGQGTADIQKKIKNE 145
                 89*********9999999999655 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.0002
        QIL1   3 dqGlWgsseeteelykkakeyipPyvdevkkklclev 39 
                 +qG+W ++ ++ +++++ k+ i  y+++ + +++le 
  EEA18570.1 414 KQGIWWDGRRGFDCLRDEKNRIVAYIKDREGQFVLEY 450
                 79*************************9898887774 PP

>> GXWXG  GXWXG protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1   5.9e-05      0.26      25      54 ..     586     615 ..     579     619 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 5.9e-05
                 TTSHHHHHHHHTTEEEEEEEETTEEEEEEE CS
       GXWXG  25 TgHpldglLealkWyGkeFrsaedvdPllf 54 
                 TgH + ++Le+lkW+ +  + + + +P+ +
  EEA18570.1 586 TGHTTVEILETLKWFFQYLKKRYNMTPVKI 615
                 9****************9999999999855 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (648 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1212  (0.0676); expected 358.6 (0.02)
Passed bias filter:                      570  (0.0317921); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.26s 00:00:00.89 Elapsed: 00:00:00.42
# Mc/sec: 4645.76
//
Query:       EEA18571.1  [L=403]
Description: hypothetical protein PMAA_008590 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.1e-09   36.4   0.0    5.8e-09   36.0   0.0    1.2  1  RVT_2        Reverse transcriptase (RNA-dependent DNA polymer
  ------ inclusion threshold ------
      0.019   14.8   0.0      0.029   14.2   0.0    1.3  1  FrhB_FdhB_C  Coenzyme F420 hydrogenase/dehydrogenase, beta su


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.0   0.0   6.4e-13   5.8e-09      56     127 ..     334     402 ..     322     403 .] 0.90

  Alignments for each domain:
  == domain 1  score: 36.0 bits;  conditional E-value: 6.4e-13
       RVT_2  56 PvirldsvrLllalaaeeelvvhqldvdsafLnaeldeevyvkqPpGfeidreeekvykLnkslyGlkqapl 127
                 P+ + +  ++l ++aa  +l + q +   af+na+ldee++++  pG+    e++k+y+Lnk+lyGl+++pl
  EEA18571.1 334 PIRKAKGKQILDSIAARFDLELKQYNAVNAFVNAKLDEEIFMRIAPGYR---EPGKIYRLNKALYGLRRSPL 402
                 6666667788999**********************************95...68**************9997 PP

>> FrhB_FdhB_C  Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   3.2e-06     0.029     119     153 ..     325     359 ..     315     361 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 3.2e-06
  FrhB_FdhB_C 119 dddegvstvlvrtekgeellekaveageleleeld 153
                  + +++++tv +r +kg+++l++++++ +lel++++
   EEA18571.1 325 NPSGSWTTVPIRKAKGKQILDSIAARFDLELKQYN 359
                  56889***************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (403 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       501  (0.0279436); expected 358.6 (0.02)
Passed bias filter:                      462  (0.0257683); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.21s 00:00:00.70 Elapsed: 00:00:00.38
# Mc/sec: 3191.48
//
Query:       EEA18572.1  [L=351]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-06   27.9   0.1    2.6e-06   27.3   0.1    1.3  1  RVT_2     Reverse transcriptase (RNA-dependent DNA polymerase
  ------ inclusion threshold ------
       0.03   14.2   0.0       0.06   13.2   0.0    1.5  1  Flg_hook  Flagellar hook-length control protein FliK


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.1   2.9e-10   2.6e-06     165     232 ..       4      75 ..       1      83 [. 0.84

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 2.9e-10
       RVT_2 165 lyvddlliagsdikil..edvkkelakkfklkdlgkvskfLGieiaq..eaggiklsladyiakvvkkfelt 232
                  yvdd+++a ++++ l  + v ++l +k++++   +++ fLG+ i++  ++  i ls+a yi k++k ++  
  EEA18572.1   4 FYVDDIVLAYKKSRQLeaDSVLNQLRAKYNISGGEDLEWFLGMRIIRdrSNKVIWLSQATYIDKIAKLADTR 75 
                 7********9999876225799***********************986567889***********9977654 PP

>> Flg_hook  Flagellar hook-length control protein FliK
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   6.7e-06      0.06      37      67 ..     240     270 ..     229     288 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 6.7e-06
                 EEEEEEEE-SCHHHHHHHHTHHHHHHHHHCC CS
    Flg_hook  37 qlsvqltaenpetrelLeqnlprLreaLaaa 67 
                   ++++  +n++t+ lLe+++prLr+ L+  
  EEA18572.1 240 TPTLHVFCDNKQTLGLLEKDAPRLRTKLRHV 270
                 45899**********************9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (351 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       439  (0.0244855); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.22s 00:00:00.69 Elapsed: 00:00:00.39
# Mc/sec: 2688.66
//
Query:       EEA18573.1  [L=175]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.5e-09   37.1   0.2    1.4e-08   35.2   0.2    1.9  1  Pro_CA    Carbonic anhydrase


Domain annotation for each model (and alignments):
>> Pro_CA  Carbonic anhydrase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.2   0.2   7.7e-13   1.4e-08       2      69 ..      41     104 ..      40     172 .. 0.71

  Alignments for each domain:
  == domain 1  score: 35.2 bits;  conditional E-value: 7.7e-13
                 EEEEETTTTS-HHHHTTS-TTSEEEEEETTG---TT-HHHHHHHHHHHHTS--SEEEEEEETT-HHHH CS
      Pro_CA   2 lvigCsDSRvppelitdagpGdlFvvrnvgnlvppadssvlaaleyAvevlkvkhivVlGHskCGavk 69 
                 +v++C+D Rv+p  ++d ++ d+F +rn g  v p   + + al+yA+   +  +i+++ H +CG   
  EEA18573.1  41 VVVTCCDIRVNPYEFLDLKITDVFHLRNTGGRVGPL-INDIVALDYAI---GLTEIMIIHHLDCGTTF 104
                 89*******************************776.556778****8...57889*********865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (175 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       261  (0.0145574); expected 358.6 (0.02)
Passed bias filter:                      250  (0.0139439); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.25s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 1286.16
//
Query:       EEA18574.1  [L=488]
Description: FAD-dependent monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.8e-24   86.7   0.0    2.5e-24   86.2   0.0    1.2  1  FAD_binding_3  FAD binding domain
    3.4e-06   26.5   0.3    8.2e-06   25.3   0.2    1.7  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
    0.00015   21.1   3.9     0.0077   15.5   1.4    2.2  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
     0.0002   21.5   1.1    0.00064   19.9   1.1    1.9  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
    0.00031   20.4   0.0    0.00047   19.8   0.0    1.4  1  DAO            FAD dependent oxidoreductase
    0.00039   19.6   3.6    0.00039   19.6   3.6    1.7  2  FAD_binding_2  FAD binding domain
  ------ inclusion threshold ------
      0.062   12.5   0.3       0.11   11.7   0.3    1.3  1  Thi4           Thi4 family
      0.084   12.2   2.6       0.12   11.6   2.6    1.3  1  FAD_oxidored   FAD dependent oxidoreductase
      0.087   11.8   1.0       0.69    8.9   1.0    2.0  1  Lycopene_cycl  Lycopene cyclase protein
       0.13   10.9   0.9       0.26   10.0   0.9    1.4  1  HI0933_like    HI0933-like protein
       0.13   12.8   3.5       0.27   11.8   1.3    2.4  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
       0.15   12.2   0.0       0.34   11.1   0.0    1.5  1  CH_2           CH-like domain in sperm protein
       0.43    9.6   4.5       0.43    9.6   3.2    1.6  2  GIDA           Glucose inhibited division protein A


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.2   0.0   1.8e-27   2.5e-24       3     349 .]       8     373 ..       6     373 .. 0.77

  Alignments for each domain:
  == domain 1  score: 86.2 bits;  conditional E-value: 1.8e-27
                    EEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSSS--EEEHHHHHHHHHTT-HHHHHHHSEECCCCEEEEEEECCCC..CEEEEEHHCHHCS CS
  FAD_binding_3   3 dVlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlpradglnqrtmellrqlGledrilaegapnelmgealynelsdt..pkaradlelessp 96 
                     V++VG+G  Gl +a+   +aG++++++e+ + +   + + g+ +   ++l+q G  + + +e++p e  + +l    s +  ++    l  +  +
     EEA18574.1   8 RVIVVGGGVGGLAAAHAFEKAGIDHIVLERGEIAPARGASIGIYPHGARILQQFGTLQAVDDETYPIERAKNFLPDG-SLIanSELFRFLR-QYHG 101
                    79******************************************************************999999888.2223222222333.5666 PP

                    T-CEE--HHHHHHHHHHHHHHHTEEETCSEEEECCEECCCCCCCEEEECCTTEEEEEEEEEEEE--GTT-HHH....HHHTGGEEEEEEEEEEEEE CS
  FAD_binding_3  97 ervtvypqteleriLvehaeerglqvrfktevesleqdeegvtaevrdketgeeetvrakYlvGaDGgrStvr....ktlgiefegeetvyeagvl 188
                      + v+   +++ i+++ ++ + l ++ + +v+ + + e++v+  + d + +e      + + G DG++S vr    +++   ++g+ t  e + l
     EEA18574.1 102 YPIPVLERRRFLEIMYDGLSDKSL-IKSHSKVVDIIDSEDNVKVILADGTVEEG-----DLVLGVDGVHSLVRslmwRNANAAIPGFITANEKKTL 191
                    6777888899999*****776665.677777888**************987777.....9*************44443566777777777666666 PP

                    EEEEEC..-SCCCTTC.....CEEEEECCTTEEEEEECCETEEEEEEEEECCE-GGGS..CCCHHHHHHHHHHHHHHTTSSCEEEEE...E..... CS
  FAD_binding_3 189 dvlfda..dlsdivep.....lvlilsaesrgvmviPlentlerfyvqvearaekeer..sekfteeevkarlreivgektldveie...e..... 267
                     +  +    +s++ ++     l+  + + +++++++     +++  ++v +++++  +   +k t++++ +r+ e ++ +  ++++    +     
     EEA18574.1 192 HADYSLliGFSETGSHmspsdLYCTHYDGKSFLTIG---G-KKHTFWFVFFKNDRVHWpaLPKWTQADAERRAAECMDCPISETQVFgelWktair 283
                    555544446776666677564444444444443333...3.3468888899999999945577888888888888888888888774333411111 PP

                    EEEEEEEEEEESSSEETTEEE-GGGTEEE-STTSHHHHHHHHHHHHHHHHHHHHHTTS........S-GGGGHHHHHHHHHHHHHHHHHH CS
  FAD_binding_3 268 vsawtvaqrvaekyrkgrvflaGDAaHihpPtgGqGlNtaiqDavnLawkLaavlkGe........AkeelLdtYeeerravaqavvdfa 349
                    ++ ++v++ + e++  grv laGDA+H ++P  G+G N+a++ +v L   L ++++++        A ++lL  Y+++r+ + ++ +df+
     EEA18574.1 284 TELVNVEEGLFEHMFFGRVVLAGDAVHKMTPNIGLGGNSAMESVVVLTNLLHKAIQEHpegkpdkaAIQNLLHEYQKDRQVRMRQFIDFS 373
                    45578899999**************************************999999975444344446789**************999986 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.3   0.2   5.9e-09   8.2e-06       1      49 [.      10      61 ..      10     115 .. 0.75
   2 ?   -2.2   0.0       1.4   1.9e+03     229     269 ..     126     165 ..     104     189 .. 0.64

  Alignments for each domain:
  == domain 1  score: 25.3 bits;  conditional E-value: 5.9e-09
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEkgni....gnsiyrypkemtfisps 49
                 i++G+G  Glaaa++++kag+ d+++lE+g+i    g+si  yp   +++ + 
   EEA18574.1 10 IVVGGGVGGLAAAHAFEKAGI-DHIVLERGEIaparGASIGIYPHGARILQQF 61
                 89*******************.689*****98555578999999999888743 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.4
  Pyr_redox_3 229 vlfnaevkeikekeeeykvktedgkkvevkddvvlatGykp 269
                  + ++++v +i ++e ++kv  +dg+ ve+ d v+ + G ++
   EEA18574.1 126 IKSHSKVVDIIDSEDNVKVILADGT-VEEGDLVLGVDGVHS 165
                  4456667777777788888888874.444343333344444 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   1.4   5.6e-06    0.0077       1      38 [.       7      44 ..       7      58 .. 0.87
   2 !    5.9   0.0    0.0048       6.6     201     239 ..     127     165 ..     114     190 .. 0.82

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 5.6e-06
                 CSEEEE--SHHHHHHHHHHHHHTS-EEEEETTHCHHHC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  1 kdvvviGgGpAGlaaaltlaqagakvtlvelegtclng 38
                 ++v+v+GgG++Glaaa+   +ag++ +++e+++  + +
   EEA18574.1  7 FRVIVVGGGVGGLAAAHAFEKAGIDHIVLERGEIAPAR 44
                 58***********************9999877666655 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0048
                  EESCEEEEEEETTEEEEEEETTSCEEEESEEEE-S-EEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 201 klgtsvkeidgngeklevvledgeeidadlvvvavGvrp 239
                  k +++v++i++ +++++v+l dg++++ dlv+   Gv  
   EEA18574.1 127 KSHSKVVDIIDSEDNVKVILADGTVEEGDLVLGVDGVHS 165
                  567889999999999****************98888765 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   1.1   4.6e-07   0.00064       1      38 [.      11      48 ..      11      69 .. 0.80

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 4.6e-07
                   EE--SHHHHHHHHHHHCCTEEEEEE-SSSSSSGGG-EE CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekrdrlGGraasy 38
                   +vG+G++Gl+aA++  kag+d  +le+++    r as+
     EEA18574.1 11 VVGGGVGGLAAAHAFEKAGIDHIVLERGEIAPARGASI 48
                   8**************************98877776666 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.0   3.4e-07   0.00047       1      44 [.       8      51 ..       8     132 .. 0.84

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 3.4e-07
                EEEEECTSHHHHHHHHHHHHTT..EEEEESSSSTTSSGGGSSEEEE CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..VtllekgdiagsgaSgrnsgll 44
                +v+++GGG+ Gl++A++  ++g   ++le+g +++  a g++ g+ 
  EEA18574.1  8 RVIVVGGGVGGLAAAHAFEKAGidHIVLERG-EIA-PARGASIGIY 51
                59****************999**********.555.5666666655 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   3.6   2.8e-07   0.00039       2      32 ..       9      39 ..       8      48 .. 0.92
   2 ?   -3.6   0.0       3.1   4.2e+03     225     256 ..     315     346 ..     303     357 .. 0.76

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 2.8e-07
                   EEEE--SHHHHHHHHHHHHTTT-EEEEESSS CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGlkvavvekeq 32
                   viV+G+G++GLaAA++  +aG + +v+e ++
     EEA18574.1  9 VIVVGGGVGGLAAAHAFEKAGIDHIVLERGE 39
                   9**************************9986 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 3.1
                    -S-HHHHHHHCTTSSEES..TT-EEEEEEEET CS
  FAD_binding_2 225 vtGdglalalragaalnddrmeevqfhPtslv 256
                    + G g  +a ++ + l++ +  ++q+hP + +
     EEA18574.1 315 NIGLGGNSAMESVVVLTNLLHKAIQEHPEGKP 346
                    56778888888888889989999999998877 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.3   7.8e-05      0.11      20      60 ..       9      49 ..       4      68 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 7.8e-05
                EEEE--SHHHHHHHHHHHHCTTS-EEEEES.SSS--TTTTTT CS
        Thi4 20 vvivGaGssGLtaayylakkpdlkvailer.svspGGGawlG 60
                v++vG+G  GL+aa+ + k+ ++  ++ler +++p  Ga  G
  EEA18574.1  9 VIVVGGGVGGLAAAHAFEKA-GIDHIVLERgEIAPARGASIG 49
                9******************9.********8568888887766 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   2.6     9e-05      0.12       2      31 ..       9      38 ..       8      41 .. 0.93

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 9e-05
  FAD_oxidored  2 vvVvGGgpaGvaAAiaAaraGakvlLveer 31
                  v+VvGGg++G+aAA a  +aG   +++e+ 
    EEA18574.1  9 VIVVGGGVGGLAAAHAFEKAGIDHIVLERG 38
                  9*********************99999986 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   1.0    0.0005      0.69       2     143 ..       9     165 ..       8     177 .. 0.67

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0005
  Lycopene_cycl   2 vvviGaGpAglslAarlteakpglkvvlieaspsllfpnny..vWsdefedlga....leecvehsWs..gtivylddgkkillg......raYg. 82 
                    v+v+G+G  gl+ A+    +k+g+  +++e ++  +  +     +  +++ + +    l+++ + +++  ++   l+dg+ i  +      r+Y+ 
     EEA18574.1   9 VIVVGGGVGGLAAAHAF--EKAGIDHIVLERGEIAPARGASigIY-PHGARILQqfgtLQAVDDETYPieRAKNFLPDGSLIANSelfrflRQYHg 101
                    89***************..9*********9999775444432222.22222211233377777777751134445777777777677777755542 PP

  Lycopene_cycl  83 ....rvsskrlkeellerlvengvklleakvesveeeeageslvvleggrkirarlvvdarglas 143
                         ++++r+ e +   l ++  +  ++kv  + ++e+ ++ v+l++g   ++ lv+   g+ s
     EEA18574.1 102 ypipVLERRRFLEIMYDGLSDKSLIKSHSKVVDIIDSED-NVKVILADGTVEEGDLVLGVDGVHS 165
                    223257788888888888888888888888888888888.8888888887777777776666555 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.9   0.00019      0.26       2      33 ..       8      39 ..       7      44 .. 0.92

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00019
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SSS CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVlllekak 33
                 +viv+GgG  Gl aA + +k+g + ++le+++
   EEA18574.1  8 RVIVVGGGVGGLAAAHAFEKAGIDHIVLERGE 39
                 79**************************9875 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   1.3    0.0002      0.27       1      31 [.       8      38 ..       8      44 .. 0.93
   2 ?   -0.5   0.0       1.4   1.9e+03       7      34 ..     319     346 ..     319     369 .. 0.64

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.0002
                EEEEECSSHHHHHHHHHHHHTTSEEEEEESS CS
   Pyr_redox  1 kvvvvGgGyiglElAgalaelgkkVtvvers 31
                +v+vvGgG+ gl +A a+ + g +  v+er+
  EEA18574.1  8 RVIVVGGGVGGLAAAHAFEKAGIDHIVLERG 38
                79********************999999987 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 1.4
                 SSHHHHHHHHHHHHTTSEEEEEESSSSS CS
   Pyr_redox   7 gGyiglElAgalaelgkkVtvversdkl 34 
                 gG++++E   +l++l +k    + + k+
  EEA18574.1 319 GGNSAMESVVVLTNLLHKAIQEHPEGKP 346
                 8999999999999987766555555555 PP

>> CH_2  CH-like domain in sperm protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00025      0.34      29      68 ..     353     394 ..     346     415 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00025
        CH_2  29 eilkkyy.pklvdlhnysngsslaaklnNWetL.ekvlkklg 68 
                 ++l++y+  ++v + ++ + ssla+k++ Wet   k+l+++ 
  EEA18574.1 353 NLLHEYQkDRQVRMRQFIDFSSLATKIQAWETTwYKILSRVI 394
                 67888874578*********************9999998865 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   3.2   0.00031      0.43       2      25 ..       9      32 ..       8      51 .. 0.89
   2 ?   -3.3   0.0       2.6   3.6e+03      94     133 ..     109     147 ..     103     158 .. 0.55

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00031
                EEEE-SSHHHHHHHHHHHHTT--E CS
        GIDA  2 viViGgGhAGceAAlaaarlGakv 25
                viV+GgG  G++AA a  ++G++ 
  EEA18574.1  9 VIVVGGGVGGLAAAHAFEKAGIDH 32
                9********************975 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 2.6
                 HHHHHHHHHHHHHTSTTEEEEES-EEEEEECTTEEEEEEE CS
        GIDA  94 relyskevteklenepnleiieeeveeliveekkvkgvvt 133
                 r+++ + + + l+++  ++    +v ++i++e++vk+++ 
  EEA18574.1 109 RRRFLEIMYDGLSDKSLIKSH-SKVVDIIDSEDNVKVILA 147
                 566666666666665555543.344444454555554433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (488 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       545  (0.0303977); expected 358.6 (0.02)
Passed bias filter:                      526  (0.0293379); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.62u 0.31s 00:00:00.93 Elapsed: 00:00:00.47
# Mc/sec: 3137.55
//
Query:       EEA18575.1  [L=176]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.9e-29  100.6   0.1    7.7e-29  100.5   0.1    1.0  1  DUF3237   Protein of unknown function (DUF3237)


Domain annotation for each model (and alignments):
>> DUF3237  Protein of unknown function (DUF3237)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.5   0.1   4.3e-33   7.7e-29       1     149 []       9     169 ..       9     169 .. 0.89

  Alignments for each domain:
  == domain 1  score: 100.5 bits;  conditional E-value: 4.3e-33
                 --EEEEEEEEEEE---EEEEE...ETEEEEEEEEEEEEEES.....TT--EEE-ST-EEEEEE-T.TS-EEEEEEEEEEETTS-EEEEEEEEEEE--GG CS
     DUF3237   1 Pslepaftlevkleapvpige...gpgkrnivpitgGtikg.....prldgevlpgGaDwiridp.ggtarldaryvlktddgaliyirytGvvtldee 90 
                 P++ pa+   v++ a+  +g    gp ++  +++ +Gt+++     p++++e+  +GaDw+ +d+ +++ar+d+++v++t+dga+i++ y+Gvvtld++
  EEA18575.1   9 PTVVPAINQVVDVIAKRVVGVrenGP-TLIHFEFGKGTLETvegfePAFKAEIF-HGADWLSFDSdEKHARIDVKAVAQTEDGAIINFPYHGVVTLDKD 105
                 78889999999998777777633344.67777777*******************.**********999******************************* PP

                 GHHHHHHT-..---GGG-E.EEEEEEEEESSGGGGGGGSS-EEEEEEEESS.E.....EEEEEEEE CS
     DUF3237  91 vlavlgggekkesspteyg.frthptfetgdekykwLnnavfvGsgrfrve.g.....veykvyev 149
                 v+a ++ ++  +s++ ++g ++ +  f +g+ek+k L+n++f+G++r++ + +     ve ++++v
  EEA18575.1 106 VMACFNMDP--TSKTIPFGaSTNTHYFHSGAEKLKDLENMTFIGNSRMIINqEtrgiqVETRISRV 169
                 *******88..667899**7777789***********************88536789999999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (176 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       267  (0.0148921); expected 358.6 (0.02)
Passed bias filter:                      250  (0.0139439); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.23s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1305.89
//
Query:       EEA18576.1  [L=273]
Description: 2-(R)-hydroxypropyl-CoM dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.5e-52  176.6   0.6    8.9e-52  176.0   0.6    1.2  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
    2.4e-48  164.2   0.2    3.9e-48  163.5   0.2    1.3  1  adh_short     short chain dehydrogenase
    1.6e-07   31.5   0.2      3e-07   30.5   0.2    1.5  1  KR            KR domain
    1.7e-05   24.4   0.1       0.08   12.4   0.0    3.1  2  Epimerase     NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  176.0   0.6     2e-55   8.9e-52       1     233 [.      18     270 ..      18     271 .. 0.87

  Alignments for each domain:
  == domain 1  score: 176.0 bits;  conditional E-value: 2e-55
                   TTTTSHHHHHHHHHHHTT-EEEEE.ESSGG......H..HHHHHHHHHHTTSE...EEE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EG.CS CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvlt.dlnee......a..kkrveelaeelgae...vlecDVtdeeqvealveevvekfgklDilvnnagiapk.lk 84 
                   G  sg+GraiA a+a++G +++++ dl+ e      +  +++ e + +e+g+    +++cDV   e+v+++++ +ve+ g+lD++vnnagi ++  +
    EEA18576.1  18 GSSSGLGRAIALAFASHGTKLIVCaDLQPEprkgsdGenEATHEMICREYGEGkarFVKCDVGVSEEVKQMIQVAVEEGGRLDVIVNNAGIGHTdPT 114
                   5679****************7765266544111111122455666778887433236************************************9889 PP

                   S-GGGH-HHHHHHHHHHHTHHHHHHHHHHHHHCTSC........CEEEEEEEGGGTSBSTTTT.HHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE- CS
  adh_short_C2  85 gpfletsreefdraldvnlyslfllakaalplmkeg........gsivnlssvgaervvpnyn.aygaaKaalealtrylAvelgpkgiRvNavspg 172
                    ++++++++e+dr + +n++++++ +k+ l  m  +        g+i+n+ssv + ++ ++ + ay+a+Kaa  +ltr++A ++++++i+ Na +pg
    EEA18576.1 115 LRLHQLPDSEWDRFIRINATGVYNGSKHSLAQMVTQepdakgsrGRIINVSSVMGLVASAGGAgAYNASKAASLNLTRQIALDYARDRITANALCPG 211
                   99999*************************9555444788889999**********99877777********************************* PP

                   -BHCTGGGGSTTHHHHHHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEESTTG CS
  adh_short_C2 173 pikTlaasgikgfdelleelearaplgrlgtpeevaeaalfLasdeasyitGqtlvvDgGl 233
                   +ikT ++++++  +   +++ + +p g +  +++va  a+fLasd+a+ +tG  l vDgG+
    EEA18576.1 212 LIKTAMTRDLD--ETAAQAFLNATPWGDWLGADDVAGGAVFLASDDAAVVTGIALPVDGGY 270
                   **********8..78889999***************************************9 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  163.5   0.2   8.6e-52   3.9e-48       1     193 [.      12     224 ..      12     226 .. 0.87

  Alignments for each domain:
  == domain 1  score: 163.5 bits;  conditional E-value: 8.6e-52
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEEEE.SCHHHH.......HHHHHHHHHT..TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---S.. CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvvvd.rseekl.......eevakelkee..gakalaiqvDvtdreevealvekavkklgkldvLvnNAGi.. 87 
                 kv++vtG ssG+Graia ++a+ G k++v++  ++e+        e++++ + +e  + ka ++++Dv  +eev+++++ av++ g+ldv+vnNAGi  
  EEA18576.1  12 KVAVVTGSSSGLGRAIALAFASHGTKLIVCAdLQPEPRkgsdgenEATHEMICREygEGKARFVKCDVGVSEEVKQMIQVAVEEGGRLDVIVNNAGIgh 110
                 89***************************6514444331111111445555555578899*************************************66 PP

                 .S--SSGGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHH......HCTTEEEEEEEEGGGTSB-TTBH.HHHHHHHHHHHHHHHHHHHHGGGTEEEEEEE CS
   adh_short  88 .tgsgpfselseeewervievNltgvflltravlpaml......kqssGrIvnvsSvagkvpvagva.aYsAsKaavagltrslakelaptgirvnava 178
                    +   ++l ++ew+r i +N tgv++ +++ l +m+      k+s+GrI+nvsSv g+v++ag+a aY AsKaa   ltr++a ++a+++i+ na++
  EEA18576.1 111 tDPTLRLHQLPDSEWDRFIRINATGVYNGSKHSLAQMVtqepdaKGSRGRIINVSSVMGLVASAGGAgAYNASKAASLNLTRQIALDYARDRITANALC 209
                 555666789999***********************************************9999876449****************************** PP

                 ESSBSSHHHHHHCTH CS
   adh_short 179 PGlvdTdmakelrek 193
                 PGl++T+m+++l e+
  EEA18576.1 210 PGLIKTAMTRDLDET 224
                 *********998876 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.5   0.2   6.6e-11     3e-07       4     118 ..      15     138 ..      13     193 .. 0.69

  Alignments for each domain:
  == domain 1  score: 30.5 bits;  conditional E-value: 6.6e-11
                 EEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-......EEEE----TT-HHHHHHHHHHHHHHSS---EEEE--------- CS
          KR   4 litGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealga......evevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdkl 96 
                 ++tG   gLG+++a   a++g + +v+   ++++++ s+ + ++ +++ +      + ++v++Dv  +++v+++++ + +e++++  +++ Ag+ ++++
  EEA18576.1  15 VVTGSSSGLGRAIALAFASHGTKLIVCADLQPEPRKGSDGENEATHEMICreygegKARFVKCDVGVSEEVKQMIQVAVEEGGRLDVIVNNAGIGHTDP 113
                 89********************99999988875444444333333333222234469*************************************99776 PP

                 ...TTT--HHHHHHHHTTTTHHHHH CS
          KR  97 ...leemtaedleqvlapKvkGawn 118
                    l ++ ++++++ ++   +G+ n
  EEA18576.1 114 tlrLHQLPDSEWDRFIRINATGVYN 138
                 2224555667777777766666544 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.4   0.0   1.8e-05      0.08       2      77 ..      15     111 ..      14     116 .. 0.82
   2 !    8.5   0.0   0.00027       1.2     125     228 ..     120     254 ..     113     264 .. 0.68

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 1.8e-05
                 EEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC................EEEE--TT-HHHHHHHHH...HH..T-SEEEE--S---H CS
   Epimerase   2 lVtGatGfiGsalvkallekgyevigldrlssasntarledl................elveldltdrsalerlfk...ee..qpdavihlAavggv 77 
                 +VtG +  +G+a++ a++++g ++i+ + l+ + +++++ +                 ++v++d+  +++++++++   ee  + d++++ A++g+ 
  EEA18576.1  15 VVTGSSSGLGRAIALAFASHGTKLIVCADLQPEPRKGSDGENeathemicreygegkaRFVKCDVGVSEEVKQMIQvavEEggRLDVIVNNAGIGHT 111
                 8**********************88888887777766666667999********************9998877665222333688888888888876 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00027
                 SSBSTCSTTS----SSHHHHHHHHHHHHHHHHHHHHT-EEEEEEESEEESTT.....S-TTS.TTSHHHHHHHHHHT...TSS................ CS
   Epimerase 125 qpkeettltgplkpnspYaaaKlageklveayaaqyglnaiilrlfnlyGpr.....ngege.vsrvipalirkile...gkq................ 198
                  p++e      ++ +  Y  +K+   ++v++  ++ g +  i+++++++G        g  +  +     l r+i++   + +                
  EEA18576.1 120 LPDSEWDRFIRINATGVYNGSKHSLAQMVTQEPDAKGSRGRIINVSSVMGLVasaggAGAYNaSKAASLNLTRQIALdyaR-Dritanalcpgliktam 217
                 47888888888899999****************************999998865534222221222222234444444441.14455555555555555 PP

                 .......SEEEETTST-EEEEEEHHHHHHHHHHHHHH CS
   Epimerase 199 .......evtllgdgtalRdflyveDvaeaillvleh 228
                            + + t++ d+l ++Dva + ++++  
  EEA18576.1 218 trdldetAAQAFLNATPWGDWLGADDVAGGAVFLASD 254
                 5555544555555899999999999999999988776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (273 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       341  (0.0190195); expected 358.6 (0.02)
Passed bias filter:                      289  (0.0161191); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.40
# Mc/sec: 2028.45
//
Query:       EEA18577.1  [L=601]
Description: dimethylaniline monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.2e-15   56.2   0.0    1.8e-14   53.7   0.0    1.9  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
      4e-14   51.9   0.0    5.9e-06   25.0   0.0    3.2  3  FMO-like       Flavin-binding monooxygenase-like
    1.2e-07   31.2   0.0    1.1e-06   28.1   0.0    2.4  4  K_oxygenase    L-lysine 6-monooxygenase (NADPH-requiring)
      1e-05   24.9   0.0    9.8e-05   21.7   0.0    2.1  2  Thi4           Thi4 family
    1.2e-05   25.5   0.0    2.9e-05   24.2   0.0    1.7  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
    0.00017   20.9   0.0    0.00089   18.6   0.0    2.0  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    0.00026   21.0   0.1      0.054   13.5   0.1    3.2  2  NAD_binding_9  FAD-NAD(P)-binding
    0.00065   20.2   0.2         15    6.3   0.0    3.7  3  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase


Domain annotation for each model (and alignments):
>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.7   0.0   7.9e-18   1.8e-14       2     196 ..      14     214 ..      13     229 .. 0.83
   2 ?   -0.3   0.0      0.23   5.1e+02     245     276 ..     342     372 ..     315     382 .. 0.74

  Alignments for each domain:
  == domain 1  score: 53.7 bits;  conditional E-value: 7.9e-18
  Pyr_redox_3   2 IiGaGPaGlaaaielkkagl.edylilEkg.nignsiyrypkemtfispsftsekleipdlnaiseetspafslkeeklsrkealeYlrevaksfel. 96 
                  IiGaG  Gl aa +  ++    ++li++ + ++g  +++ +   +++       +++++ +n i +  sp+ + ++++++++ + +Yl+++a+ ++l 
   EEA18577.1  14 IIGAGWYGLVAARTYLRVRPdVNLLIIDSDsTVGGVWSERRLYPNLVA------QVNLGLFNYIDTPMSPEGMNDKRQVTGRMIHNYLQKYAEDHDLl 105
                  9********999886655432589*****9778888777666666666......35566678899999999888999*******************97 PP

  Pyr_redox_3  97 .piklfeeVesvkkedegfevetske..tyeAkkviiAtGefdkPnklnipGee.klvkhyskv.....kefhkyagqkvvViGgknSavDaAlelvr 185
                   +i+ +++Ve++++  +g +++ +++   + A k+++  G  ++Pn+++++ e+ k ++++s +     +e++k + q+v+V+G+  Sa Da + l  
   EEA18577.1 106 sRIRFNTHVEKIERGPRGWRLRFRNSpdLLDAGKLMVGPGVTSIPNMPQYSPENvKVPIVHSRDlgesfTELQKNEYQHVMVVGAAKSAYDAVYLLLT 203
                  78************999998887775449************************94455554433342226677777899******************* PP

  Pyr_redox_3 186 kgaeVtvvtrg 196
                  +g++Vt+v+r 
   EEA18577.1 204 MGKKVTWVIRP 214
                  ********985 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.23
  Pyr_redox_3 245 ykvktedgkkvevkddvvlatGykpdlsflkk 276
                   ++++++g++ve+ d++v++tG+  ++ ++++
   EEA18577.1 342 RTMSFKSGRSVES-DFIVMCTGWGDHFAMFDD 372
                  4678999999876.677777**9988887764 PP

>> FMO-like  Flavin-binding monooxygenase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.0   0.0   2.6e-09   5.9e-06       4     209 ..      12     208 ..      10     219 .. 0.77
   2 ?    1.6   0.0     0.032        71     289     341 ..     322     374 ..     314     380 .. 0.81
   3 !   20.9   0.0   4.4e-08   9.9e-05     337     445 ..     416     528 ..     410     539 .. 0.83

  Alignments for each domain:
  == domain 1  score: 25.0 bits;  conditional E-value: 2.6e-09
    FMO-like   4 vaviGaGvsGlasikccl..eegleptcfersddiGGlwrfkenveeGrasiyksvvsnsskemscfsdfplpedypn...flhnsklleylklfakef 97 
                 va+iGaG  Gl++ ++ l    +++    +    +GG+w           ++y  +v+ +   +  + d p+  +  n    +    + +yl+++a++ 
  EEA18577.1  12 VAIIGAGWYGLVAARTYLrvRPDVNLLIIDSDSTVGGVWS--------ERRLYPNLVAQVNLGLFNYIDTPMSPEGMNdkrQVTGRMIHNYLQKYAEDH 102
                 9*************9986225789999999999******5........3589********************7665552335777889*********** PP

    FMO-like  98 dllkyiqfkttvcsvkkrpdfstsGqwevvtekegkkesavfda..vmvctGhhvnphlplesfpGiekfkGqyfhsrd....ykepevfkgkrvlviG 190
                 dll  i+f+t+v ++++ p       w +      ++  +++da  +mv  G    p++p+ s    e+ k  ++hsrd    + e +  + + v+v+G
  EEA18577.1 103 DLLSRIRFNTHVEKIERGPR-----GWRLRF----RNSPDLLDAgkLMVGPGVTSIPNMPQYSP---ENVKVPIVHSRDlgesFTELQKNEYQHVMVVG 189
                 ***************99885.....476644....45567777755788889999999998774...67788899999822223334455567888999 PP

    FMO-like 191 lGnsggdiavelsrtaeqv 209
                    s+ d    l  + ++v
  EEA18577.1 190 AAKSAYDAVYLLLTMGKKV 208
                 8888888766665555555 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.032
    FMO-like 289 arilaGavk.vkssvkeltetsaifedgtveedidvvifatGytfafpfleesl 341
                 ++i  G v+ v+ ++  l+e +  f+ g   e+ d ++++tG+   f ++++  
  EEA18577.1 322 STIHKGDVTiVRDELGVLNERTMSFKSGRSVES-DFIVMCTGWGDHFAMFDDET 374
                 567778776368889999999999*99987765.9*************999874 PP

  == domain 3  score: 20.9 bits;  conditional E-value: 4.4e-08
    FMO-like 337 leeslvkveknkvslykkvfpanlekp...tlaiiGliqplGsilptvelqarwavrvlkGlkklpsekelleeitekkekkakrfgeskskt..iqtd 430
                 l+e   k+ ++   ly++v p    k+   +lai+G i+++ + l  + +q+ wa+  l G  +lp e+e+ +ei+e +  ++kr+ ++ +k      d
  EEA18577.1 416 LNEQTTKSPSKYWRLYRRVVPIAHAKSgdrSLAILGQIHTVQTPLV-ASIQTFWAILYLEGELNLPGEDEMAKEIAEWNAWTRKRYISQGQKFpySLYD 513
                 78888999999999*******9998874447********9998875.579******************************9999999665543114568 PP

    FMO-like 431 yiayldelaaligak 445
                 ++ y++ l + +g+ 
  EEA18577.1 514 FLPYVETLCKDLGVN 528
                 899999998888775 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.24   5.4e+02       2      47 ..       9      56 ..       8      64 .. 0.74
   2 !   28.1   0.0   4.8e-10   1.1e-06      96     227 ..      89     216 ..      78     223 .. 0.81
   3 ?   -3.9   0.0       2.6   5.9e+03     325     340 ..     348     363 ..     341     363 .. 0.82
   4 ?   -4.1   0.0       2.9   6.5e+03     232     250 ..     531     549 ..     521     570 .. 0.73

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.24
  K_oxygenase  2 ilDligiGiGpsnLsLailleevkkelkalflerqpefa..Whpgmll 47
                  +D+++iG+G + L  a +   v+ +++ l ++  ++++  W ++ l 
   EEA18577.1  9 YVDVAIIGAGWYGLVAARTYLRVRPDVNLLIIDSDSTVGgvWSERRLY 56
                 689********9999998888888899999998877653226655555 PP

  == domain 2  score: 28.1 bits;  conditional E-value: 4.8e-10
  K_oxygenase  96 kefedYlrWvasqle..eqvrfgeeveevepdeeeeeelltveskdaegeeeelearnlvlgvG..tepkiPevleklegkervvHsseylerkee.. 187
                  +  ++Yl+  a+  +  +++rf+++ve++e   +    +l+ ++     + + l a +l++g G  + p++P+   +   k  +vHs ++ e+  e  
   EEA18577.1  89 RMIHNYLQKYAEDHDllSRIRFNTHVEKIERGPRG--WRLRFRN-----SPDLLDAGKLMVGPGvtSIPNMPQYSPENV-KVPIVHSRDLGESFTElq 178
                  4558899988876444488***********99986..3455554.....6889********988546799999988766.69********99998865 PP

  K_oxygenase 188 llakkriaVvGsGqSaaeifedllrrqkkvelklvtrsea 227
                  +++ ++++VvG+ +Sa + ++ ll+  k  ++++v+r  +
   EEA18577.1 179 KNEYQHVMVVGAAKSAYDAVYLLLTMGK--KVTWVIRPGG 216
                  77789*******************9988..89***99765 PP

  == domain 3  score: -3.9 bits;  conditional E-value: 2.6
  K_oxygenase 325 eeetlevdavvlATGY 340
                  + +++e+d +v++TG+
   EEA18577.1 348 SGRSVESDFIVMCTGW 363
                  5578999*******96 PP

  == domain 4  score: -4.1 bits;  conditional E-value: 2.9
  K_oxygenase 232 ddspfvneifsPeyvdyfy 250
                   +s+f  e+fsP + + f 
   EEA18577.1 531 RKSNFLAEYFSPYRPEDFS 549
                  5788999999997777665 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.7   0.0   4.4e-08   9.8e-05      18      70 ..      10      62 ..       1      79 [. 0.84
   2 ?    0.6   0.0      0.12   2.7e+02       8      41 ..     173     205 ..     167     216 .. 0.82

  Alignments for each domain:
  == domain 1  score: 21.7 bits;  conditional E-value: 4.4e-08
                EEEEEE--SHHHHHHHH.HHHHCTTS-EEEEESSSS--TTTTTTSTTBSEEEEE CS
        Thi4 18 sDvvivGaGssGLtaay.ylakkpdlkvailersvspGGGawlGGqlfsaivvr 70
                 Dv+i+GaG  GL aa+ yl  +pd++++i+++  +  GG+w   +l+ ++v +
  EEA18577.1 10 VDVAIIGAGWYGLVAARtYLRVRPDVNLLIIDSDST-VGGVWSERRLYPNLVAQ 62
                7***************9355666********98855.5789*999999999876 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.12
                 HHHHHHHHTEEEEEEE--SHHHHHHHHHHHHCTT CS
        Thi4   8 yfedllkyaesDvvivGaGssGLtaayylakkpd 41 
                 +f++l+k   + v++vGa  s   a y l +  +
  EEA18577.1 173 SFTELQKNEYQHVMVVGAAKSAYDAVYLLLTM-G 205
                 688999999999*************9998766.4 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.2   0.0   1.3e-08   2.9e-05       1      49 [.      14      67 ..      14      79 .. 0.81

  Alignments for each domain:
  == domain 1  score: 24.2 bits;  conditional E-value: 1.3e-08
                   EE--SHHHHHHHHHHHC.C.TEEEEEE-SSSSSSGGG-EECE.TT..CEECTS- CS
  NAD_binding_8  1 IvGaGlsGlvaAylLak.a.gfdvlllekrdrlGGraasyev.pg..vrvdyga 49
                   I+GaG  GlvaA+++ + + +++ l++++ + +GG ++ +++ p+    v++g 
     EEA18577.1 14 IIGAGWYGLVAARTYLRvRpDVNLLIIDSDSTVGGVWSERRLyPNlvAQVNLGL 67
                   9***********98655357*******************999888555555554 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0     4e-07   0.00089       2     171 ..      11     211 ..      10     215 .. 0.63
   2 ?   -0.9   0.0      0.33   7.4e+02     217     237 ..     343     363 ..     326     380 .. 0.80

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 4e-07
                  SEEEE--SHHHHHHHHHHHHHTS-EEEE..E..........TTHCHHHCSHHHHCHHHHHHHHHHHHH.........................HHHHC CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxx..x..........xxxxxxxxxxxxxxxxxxxxxxxxxxx.........................xxxxx RF
  Pyr_redox_2   2 dvvviGgGpAGlaaaltlaqagakvtlv..e..........legtclnggcllskallgvaedaeias.........................evvkk 62 
                  dv++iG+G+ Gl aa+t  +   +v l+  +          +++            + +  ++ +  +                         + ++k
   EEA18577.1  11 DVAIIGAGWYGLVAARTYLRVRPDVNLLiiDsdstvggvwsERR-----------LYPNLVAQVNLGLfnyidtpmspegmndkrqvtgrmihNYLQK 97 
                  8*******************655555543333344222333222...........3333333333222344445666678887776667777744444 PP

                  HHHHCCCCHC....CTCEEEEESCEEEEETEEECTCEEEEEESEEEE---EEE-BCTCTTC.TTBEECCSECHHHHHHCC.SS-T....SEEEEES-S CS
                  xxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxx....xxxxxxxxx RF
  Pyr_redox_2  63 lnqgielllg....eevvkidpgkkkvklekkkegdeekiaydklvlAtGssprdlgipGvaenvgklvrtldsaealkl.kllp....krivvvGgG 151
                  + ++ +ll +    ++v ki++g +   l+ ++  +   ++++kl++ +G  + ++++p   ++++k+  +++s +  ++  +l+    ++++vvG+ 
   EEA18577.1  98 YAEDHDLLSRirfnTHVEKIERGPRGWRLRFRN--SPDLLDAGKLMVGPG-VTSIPNMPQYSPENVKV-PIVHSRDLGESfTELQkneyQHVMVVGAA 191
                  444444333355545577777666555554444..344899*********.56688999997777777.555554433321222256788******** PP

                  HHHHHHHHHHHHHT-EEEEE CS
                  xxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 152 yiGvElAaalaklgkevtlv 171
                    + +    l  +gk+vt v
   EEA18577.1 192 KSAYDAVYLLLTMGKKVTWV 211
                  ******************88 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.33
                  EEEETTSCEEEESEEEE-S-E CS
                  xxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 217 evvledgeeidadlvvvavGv 237
                  ++  ++g++++ d +v+++G 
   EEA18577.1 343 TMSFKSGRSVESDFIVMCTGW 363
                  478889999999999999995 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.1   2.4e-05     0.054       1      50 [.      13      55 ..      13     146 .. 0.82
   2 ?    2.7   0.0      0.05   1.1e+02     120     154 ..     325     362 ..     317     364 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.4e-05
  NAD_binding_9  1 aivGaGprGlavlerLlarakkkspleitlfdpsepgagrvwrtdqseel 50
                   ai+GaG  Gl +++  l+    + ++++ ++d +++  g+vw++++   l
     EEA18577.1 13 AIIGAGWYGLVAARTYLRV---RPDVNLLIIDSDSTV-GGVWSERR---L 55
                   8****************99...69*********9999.9***9985...3 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.05
  NAD_binding_9 120 hraevvdleera...dgqavlladgaslaadaVvLAlG 154
                    h+++v+ ++++    +++++  ++g+s++ d +v+++G
     EEA18577.1 325 HKGDVTIVRDELgvlNERTMSFKSGRSVESDFIVMCTG 362
                    66666666665422244567779**************9 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.3   0.0    0.0065        15       2      27 ..      12      37 ..      11      47 .. 0.85
   2 ?    3.7   0.0     0.041        92      37      73 ..      86     124 ..      79     131 .. 0.81
   3 !    5.8   0.0    0.0091        20       1      30 [.     184     213 ..     184     220 .. 0.94

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0065
                EEEECSSHHHHHHHHHHHHTTSEEEE CS
   Pyr_redox  2 vvvvGgGyiglElAgalaelgkkVtv 27
                v+++G+G+ gl +A ++ + + +V +
  EEA18577.1 12 VAIIGAGWYGLVAARTYLRVRPDVNL 37
                89*************99999888855 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.041
                 TSSHHHHHHHHHHHHHT..TEEEECSEEEEEEEEETTSE CS
   Pyr_redox  37 llDeeaskilqeklekn..gievllntkveeiegsedgv 73 
                 + ++++ ++lq++ e++    ++++nt ve+ie  ++g+
  EEA18577.1  86 VTGRMIHNYLQKYAEDHdlLSRIRFNTHVEKIERGPRGW 124
                 557889999*****99966679***********988874 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.0091
                 EEEEECSSHHHHHHHHHHHHTTSEEEEEES CS
   Pyr_redox   1 kvvvvGgGyiglElAgalaelgkkVtvver 30 
                 +v+vvG+  ++ ++   l  +gkkVt v r
  EEA18577.1 184 HVMVVGAAKSAYDAVYLLLTMGKKVTWVIR 213
                 79************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (601 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       388  (0.0216409); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.61u 0.29s 00:00:00.89 Elapsed: 00:00:00.44
# Mc/sec: 4077.58
//
Query:       EEA18578.1  [L=362]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (362 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       495  (0.0276089); expected 358.6 (0.02)
Passed bias filter:                      241  (0.0134419); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 2530.26
//
Query:       EEA18579.1  [L=2336]
Description: polyketide synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.3e-70  237.1   0.0    3.9e-70  236.3   0.0    1.4  1  ketoacyl-synt    Beta-ketoacyl synthase, N-terminal domain
      3e-60  204.0   0.1    4.8e-60  203.3   0.1    1.3  1  PS-DH            Polyketide synthase dehydratase
    8.8e-57  191.9   0.1      7e-56  189.0   0.0    2.5  3  KR               KR domain
    4.9e-51  174.1   0.0      1e-50  173.1   0.0    1.5  1  Acyl_transf_1    Acyl transferase domain
    1.5e-34  118.5   0.2    5.9e-34  116.6   0.4    2.0  2  Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
    1.3e-18   67.5   0.0    4.2e-18   65.8   0.0    1.9  2  KAsynt_C_assoc   Ketoacyl-synthetase C-terminal extension
    3.9e-08   33.0   0.1    9.1e-08   31.8   0.1    1.5  1  adh_short        short chain dehydrogenase
      8e-06   25.4   0.1    7.9e-05   22.1   0.1    2.2  2  Thiolase_N       Thiolase, N-terminal domain
  ------ inclusion threshold ------
      0.011   16.0   0.0       0.03   14.7   0.0    1.8  1  PP-binding       Phosphopantetheine attachment site


Domain annotation for each model (and alignments):
>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  236.3   0.0     2e-73   3.9e-70       2     253 .]      15     266 ..      14     266 .. 0.97

  Alignments for each domain:
  == domain 1  score: 236.3 bits;  conditional E-value: 2e-73
                    --EEEEEEEEEBTTBSS.HHHHHHHHHTT---EE.ES-TTSSCGTTSBTSSTTEEE-BSS.EEE..S..TTEGGTTSTHHHHHHHCTS-HHHHHHH CS
  ketoacyl-synt   2 epvaivGmgarfPggnd.veefwelLlegrdais.elpadrwdadklydpparaagkiktklggfld..vddfdpeffgispreaeamdpqqrlll 93 
                    ep+aivGm++r+Pg++d ++++we+L e+r+  + ++pa+r++ d++ +++ + +g  +++ g+fl+  ++dfdp+ff+++p ea  +dpqqr +l
     EEA18579.1  15 EPIAIVGMACRLPGAVDsAHSLWEVLKEKRSMQTpKVPASRFNIDAYLHERLDRPGSFNVSGGYFLNgnAEDFDPSFFNMTPIEAMWLDPQQRKML 110
                    79***************9**************999*********************************9*************************** PP

                    HHHHHHHHHHTS-HHTCTTGGEEEEEEESSTHHHHHHHHHHHTTGGGSCTTHHHHHSTTHHHHHHHHHHT--SSEEEEESGGGHHHHHHHHHHHHH CS
  ketoacyl-synt  94 eaawealedagltpeeldgsrvgvfiGvgagdyaalaaldedgsevkaspkavgavlanviagrisyalglrGpsvtvdtACsSslvavhaavqsl 189
                    e+++e+le+ag+t e+++gs+++vf+G+  +dy++  ++++dg+ +  +  a+g  ++  i++ri ++++l Gps+t+ tACsSs  a+h a+++l
     EEA18579.1 111 EVTYECLESAGCTLEDVKGSNTAVFVGSFTSDYQQ--MSTKDGDFRHNYA-ATGV-DPGLISARIGNTFDLNGPSFTINTACSSSIYAIHNACHAL 202
                    *******************************9965..7777776566666.9997.**************************************** PP

                    HTTS-SEEEEEEEE---SHHHHHHHHHTTBB-TTSGGGTTBTTB-SB-BB-EEEEEEEEECHHH CS
  ketoacyl-synt 190 rsgeadvalaGGvellltpeavagfsaagllspdgrckafdpkadGfvlGEGvGavvLkrleda 253
                    r+++a++a+aGGv+l+lt  +++  +++g+lsp+  c++fd++adG+ ++EG+Ga+ Lkrl+da
     EEA18579.1 203 RTRDASAAIAGGVNLILTVDQHMNTAKLGILSPTSTCHTFDASADGYGRAEGAGALYLKRLSDA 266
                    **************************************************************98 PP

>> PS-DH  Polyketide synthase dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  203.3   0.1   2.4e-63   4.8e-60       1     296 [.     939    1234 ..     939    1236 .. 0.90

  Alignments for each domain:
  == domain 1  score: 203.3 bits;  conditional E-value: 2.4e-63
                  BTTB.-EE--.-SS-EEEEEEE-S-SS.TTTSEEETTEEB--TTHHHHHHHHHHHHTS---.....-EEEEEEEE----.B--SS.-EEEEEEEEE- CS
       PS-DH    1 hpllGsrvrsasdkevvfrnrlrlaelpwLrDHrvdgkvvlPgagylemaleAarqltges....kavelrdvsilkalvlpede.pvevqlslepe 92  
                  h+llGs++ + s++++ +rn lr  +lpwL+DH ++ +vv+P+a++l+m +eA+rq+  ++    ++v++rdv++++al++p+ + ++evql+l+  
  EEA18579.1  939 HDLLGSKIVGLSKRSLAWRNVLRHVDLPWLKDHTLGREVVFPAAAHLSMSAEALRQVCDQEgieiHSVTFRDVQLMTALIIPDIDdGIEVQLRLNKM 1035
                  9*********************************************************99999999*****************989*********** PP

                  TTS-E....EEEEEEE-SS-TT.EEEEEEEEEE-------B--HHHHHHHS-SEE....E-HHHHHHHHHHHSEEE-GGG--EEEEEEETTEEEEEE CS
       PS-DH   93 edgadrawvefeifSregggeewtehatGtvrlaegaaaaavdlealqarcaepaslrsvssaefYerlaargleyGpsFqglralwrgdgealael 189 
                  +++    w++f++ S+ +g+  w +h+tG+++++  +a      ++ + + ++   +++v+++++Y++++++g+eyG+sFq l++++++ +   a +
  EEA18579.1 1036 DEDGL--WYTFTVESFVEGE--WSLHSTGSIAANYVEA------AQHEHPVDQMKLTQRVPGKTWYNAFDRVGFEYGSSFQPLSNIRTNGKYHHAAA 1122
                  66665..************9..**********988777......333333444455678*****************************744333333 PP

                  ---....GGGSSTTTT-SB-HHHHHHHHHHG..GG.----------EEEEEEEEEEE-S...-BTS--EEEEEE----SS-EEEEEEEE-SS-BEEE CS
       PS-DH  190 rlp....eelaggesayvlhPallDaalQllaaal.saeaekadaaylPvaierlrvyrpssaageelwvharleeegarsivadltlvdedGrvva 281 
                   ++    + l  ges+y+lhP+++D +lQl+++ + s    ++ ++++P++ie+l+v+ +++a + +  ++a++++ ++r ++ +++l+  +G +++
  EEA18579.1 1123 DVKvdteSGLVVGESRYLLHPSTIDGCLQLIIISInSGMHAEMAHGVVPIKIEELTVWHAKEANKTTGKSVAWTDRLDGRYFNTHTKLFSGSGDMLL 1219
                  3335566888888999*************9999998556789999**************99999********************************* PP

                  EEESEEEEE--XXXX CS
       PS-DH  282 eieglrlrrvereal 296 
                  ++++l + ++e++ +
  EEA18579.1 1220 DVKNLLCVSYEAAVP 1234
                  *********999876 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0      0.87   1.7e+03      70     100 ..     262     291 ..     258     297 .. 0.79
   2 ?   -4.1   0.0       6.4   1.3e+04      28      56 ..    1447    1474 ..    1444    1475 .. 0.77
   3 !  189.0   0.0   3.5e-59     7e-56       2     178 ..    1953    2128 ..    1952    2130 .. 0.97

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.87
                 HHHHHHHHHSS---EEEE---------TTT- CS
          KR  70 alleeikaeeppikGvihaAgvlrdklleem 100
                 +l ++i ++++p++Gvi++  v  +++++ m
  EEA18579.1 262 RLSDAI-RDGDPVRGVIRSSAVNTNGKVAGM 291
                 555555.4889*********99999888776 PP

  == domain 2  score: -4.1 bits;  conditional E-value: 6.4
                  EEEE-SS..--HHHHHHHHHHHHTT-EEE CS
          KR   28 lvllsRsaaadedskaliaelealgaeve 56  
                  ++l+s + +++++ +a+ a l+++g++ve
  EEA18579.1 1447 IMLISDE-TEKSSYSAFAAVLQDRGCNVE 1474
                  7788888.556666779999******997 PP

  == domain 3  score: 189.0 bits;  conditional E-value: 3.5e-59
                  EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TT CS
          KR    2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklle 98  
                  +y+++G+lGgLG++l+++++e+gar  v+lsRs+a +++++al++++++ ga+v+v++ D   +++v ++++e++a+   i+GvihaA+vl+d+++e
  EEA18579.1 1953 AYFLVGCLGGLGRSLTTFMLERGARDFVFLSRSGADKPEAAALVESIQKAGAKVQVFRGDAGIQADVDRAVSEVTATR-HIRGVIHAAMVLQDGMFE 2048
                  599***********************************************************************9665.****************** PP

                  T--HHHHHHHHTTTTHHHHHHHHHTTTS--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHHHHHTEEEEEE--B CS
          KR   99 emtaedleqvlapKvkGawnLhelledesldffvlfSSiagllgsagqanYaaaNaflDalaeyrrsqglpavsinwglw 178 
                  +mt ++++ +l+pKv+ a  Lh+++e+ +ldffv++SSi++++g++gqanY a+N++lD+la yr+ +glpa+s+ ++++
  EEA18579.1 2049 NMTFSQFQVALKPKVNSAVTLHKAFENVPLDFFVMTSSISATMGNPGQANYCAGNSYLDSLAWYRNLRGLPATSLILPMV 2128
                  **************************************************************************988776 PP

>> Acyl_transf_1  Acyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  173.1   0.0   5.1e-54     1e-50       2     308 ..     546     872 ..     545     880 .. 0.85

  Alignments for each domain:
  == domain 1  score: 173.1 bits;  conditional E-value: 5.1e-54
                    EEE--TT---TTTTCCHHHC-HHHHHHHHHHHHHCCH.....HHT--HHHHHH.S--TTGGGSHHHHHHHHHHHHHHHHHHHHHTT-TTSEEEE-T CS
  Acyl_transf_1   2 fvfsGqGsQwaGMGmeLlktskafaaviaradeafks.....qygfsvldvlr.nnpeglldaiqfvqpaLaavqialaellkskGvrpaavvGHS 91 
                    f+f+GqG+Qw G G++ ++t + f+ +i+++d  ++         +s+  vl  +++ +++++ +++qp+ +avqia ++l+ + G +p a vGHS
     EEA18579.1 546 FIFTGQGAQWSGLGAKAMQTFPEFRSTIDALDTILQRldaaiRPTWSLKSVLMaSADAPNINDANVAQPVCTAVQIAIIDLFATWGITPTATVGHS 641
                    9**************************9988776655111112379**99985267889************************************* PP

                    THHHHHHHHCCSSSHHHHHHHHHHHHHHHHHHTS-EECCEECS...HHHHHHH...TT.EEEEEEECCCCECCEEHHHHHHHHHHHHHCC.CCEEE CS
  Acyl_transf_1  92 lGElAaavvagalsseeallavvlrsrlmmqlagpgdmaavel..aeeeeklr.cqddvvgavansprrvvisgsqealrelvervskegvgalve 184
                     GE+Aaa++ag l + ea++a+ lr+  + ++a++g m+av+l  +  e+ +    d++v a+ nsp++ ++sg+qea+++    +sk+g++a++ 
     EEA18579.1 642 SGEIAAAYAAGLLAAPEAMVAAFLRGYAVSHNAPAGSMLAVGLglVGFEKYAGlLSDNLVIACQNSPESLTLSGTQEAVADAKSVLSKDGIFAREL 737
                    *******************************************986666666679***************************************** PP

                    CCCEECTTCCCCCCC...CHHH.HHHH.....HCCCHHCHHTTBEHCCCHHHHHHCHHHHHHHHHHHCHCCHCCHHTTS.SSEC...C-CCEECSS CS
  Acyl_transf_1 185 nvnvavhspqvdaia...dala.sala.....diaprkpkvakisstsldesserelsaeywvanlrspvrfaeavlsa.aeti...plvfveisp 267
                      + a hspq++++a   d l+ +a++     ++  r p+    ss++  e   + + a yw anlr+ v+f+eav+ + a+++    ++ +ei p
     EEA18579.1 738 PTGKAYHSPQMNDVAtiyDTLLiQAVQglsgqSLKWRRPRARWFSSVTGTEYIGQIVPASYWSANLRNRVLFDEAVACLaAAPGleqVAIAIEIGP 833
                    ***********99872224443134331111134557788888899999999************************9997666521146789**** PP

                    SSCCHCCCCCCCHHGGG-TCCCCCCTEETTSS-HHHCHHHH CS
  Acyl_transf_1 268 HslllaalektlksaedvksatlvGklkrdltdflvtflyl 308
                    Hs l+   ++  + a++  + t + +l r+++  +v++l  
     EEA18579.1 834 HSALAGPFKQICR-ANNLDRFTYIATLVREKDS-AVQLLKT 872
                    *************.8**************9998.6666554 PP

>> Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.1   0.0       7.7   1.5e+04      21      44 ..     104     127 ..     101     128 .. 0.87
   2 !  116.6   0.4     3e-37   5.9e-34       2     116 ..     275     392 ..     274     394 .. 0.97

  Alignments for each domain:
  == domain 1  score: -4.1 bits;  conditional E-value: 7.7
                      TTHHHHHHHHHHHHHHHT--GGGE CS
  Ketoacyl-synt_C  21 pngeaqaraiekalaeagvdpedv 44 
                      p+++++ ++  ++l++ag++ edv
       EEA18579.1 104 PQQRKMLEVTYECLESAGCTLEDV 127
                      77888999999*********9999 PP

  == domain 2  score: 116.6 bits;  conditional E-value: 3e-37
                      EEEEEEEEEE--..STSSSTSTTHHHHHHHHHHHHHHHT--GGGEEEEE-SS-SSHHHHHHHHHHHHHHHGGGGG.SCTSEEE-THHHH-B-GG CS
  Ketoacyl-synt_C   2 avikgsavnsdg..ahnsltapngeaqaraiekalaeagvdpedvdyveahgtgtplgDpiElealkkvfgekar.kqplavgSvKsniGHlea 92 
                      +vi+ savn +g  a +++t+p++++q+r++++a+a++g+dp +  yve+hgtgtp+gDpiE++a+ +++++ +  ++pl +g++K+niGH+ea
       EEA18579.1 275 GVIRSSAVNTNGkvAGMGITHPSKAGQERVVRQAYARSGLDPLRTAYVECHGTGTPVGDPIEAHAIGRAMNDVRPsDKPLLIGAIKANIGHSEA 368
                      79**********999*********************************************************99999***************** PP

                      GHHHHHHHHHHHHHHHTEE--BTT CS
  Ketoacyl-synt_C  93 AaGvaelikvvlalkhgvipptln 116
                      A+G+++++k++l+ ++gvip  ++
       EEA18579.1 369 ASGIFAVMKAALMTEEGVIPGVAG 392
                      ********************8765 PP

>> KAsynt_C_assoc  Ketoacyl-synthetase C-terminal extension
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.8   0.0   2.1e-21   4.2e-18       3     112 .]     398     517 ..     397     517 .. 0.86
   2 ?   -3.3   0.0       6.1   1.2e+04      53      81 ..    1437    1465 ..    1426    1481 .. 0.68

  Alignments for each domain:
  == domain 1  score: 65.8 bits;  conditional E-value: 2.1e-21
  KAsynt_C_assoc   3 peipaleegrlkVvteptpwpggi....vgvNsfGfGGsnvHviLksnk........kekrkeeskeeslprLlvlsgrteeaveallekleehl 85 
                     p i   ee+++kV+ e+tpwp g     vgv+sfG+GG+n+Hvi+++ +         +kr+++++++ +p Ll++s+++   +e++++++++  
      EEA18579.1 398 PAIL-EEEWNIKVNAETTPWPAGFserrVGVSSFGYGGTNGHVIVEAVDalhplyshGRKRRDDPQKATRPFLLPFSAHDRPTLERNVAAHAKVA 491
                     5665.589***************9999**********************9999988744444555578********************9999984 PP

  KAsynt_C_assoc  86 ldaellsllneilseeisrlpyRGyav 112
                       + +l+ l+++l  ++s++ +RG++v
      EEA18579.1 492 -PEYHLADLAYTLGVRRSKFATRGFTV 517
                     .555567778888899999******98 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 6.1
  KAsynt_C_assoc   53 eeskeeslprLlvlsgrteeaveallekl 81  
                      + ++ ++++ ++++s +te++  + ++++
      EEA18579.1 1437 DGATPSQQSVIMLISDETEKSSYSAFAAV 1465
                      22235788899999999999877766655 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.8   0.1   4.6e-11   9.1e-08       5     152 ..    1956    2102 ..    1953    2111 .. 0.88

  Alignments for each domain:
  == domain 1  score: 31.8 bits;  conditional E-value: 4.6e-11
                  EESTTSHHHHHHHHHHHHTT-EEEE.EESCHH...HHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCS CS
   adh_short    5 vtGassGIGraiakelakeGakvvv.vdrsee...kleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfsels 97  
                   +G+ +G+Gr +   ++++Ga+ +v ++rs +   ++++++++++++gak+ ++++D   +++v+++v+++   + ++  +++ A + ++g+f++++
  EEA18579.1 1956 LVGCLGGLGRSLTTFMLERGARDFVfLSRSGAdkpEAAALVESIQKAGAKVQVFRGDAGIQADVDRAVSEV-TATRHIRGVIHAAMVLQDGMFENMT 2051
                  68********************9887888755222577889999999************************.7789********************* PP

                  HHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHH CS
   adh_short   98 eeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAs 152 
                   ++++  ++  +++++ l +a+ +          v +sS+ + ++++g+a Y+A 
  EEA18579.1 2052 FSQFQVALKPKVNSAVTLHKAFENV----PLDFFVMTSSISATMGNPGQANYCAG 2102
                  ***9999999999999998887666....55689*******************96 PP

>> Thiolase_N  Thiolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.1   0.1   3.9e-08   7.9e-05      77     124 ..     180     227 ..     169     309 .. 0.88
   2 ?    0.2   0.0       0.2   3.9e+02      20      53 ..     863     898 ..     854     904 .. 0.81

  Alignments for each domain:
  == domain 1  score: 22.1 bits;  conditional E-value: 3.9e-08
                 EEEEEEHGGGHHHHHHHHHHHHHHTTSHSEEEEEEEEESTTS-EEETC CS
  Thiolase_N  77 pavtvnkvcsSglkavalaaqsiaageadvvvagGvEsmsnaptaest 124
                 p+ t+n +csS++ a+++a+ ++++ +a++++agGv  + ++++ ++t
  EEA18579.1 180 PSFTINTACSSSIYAIHNACHALRTRDASAAIAGGVNLILTVDQHMNT 227
                 789*********************************988777776664 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.2
                 TS-HHHHHHHHHHHHHHHHTS-GGGCCEE..EEEHS CS
  Thiolase_N  20 dlsaeeLlaealkallekagvdpeevdev..ivGnv 53 
                 + sa++Ll++a+  ++++ +vd eev++v    Gn+
  EEA18579.1 863 KDSAVQLLKTAGALFIQDYPVDLEEVNSVpaTTGNM 898
                 56899**********************983345555 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   0.0   1.5e-05      0.03       9      66 ..    2264    2323 ..    2257    2324 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.5e-05
  PP-binding    9 evlgvpleeid.pdtdlfdlGlDSllavellaaleeefgveiplsdlfe.hptlaelaay 66  
                    l +p+ee++    +++ +G+DS+  ++l ++l + fg+ei+   l++   t+ +la +
  EEA18579.1 2264 NMLLIPVEEFAfEGNSISVYGIDSMIGADLRNWLYKLFGLEITFQHLLApSMTILALASA 2323
                  5566788888844455778*****************************999999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2336 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       340  (0.0189637); expected 358.6 (0.02)
Passed bias filter:                      316  (0.0176251); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 1.11u 0.31s 00:00:01.42 Elapsed: 00:00:00.51
# Mc/sec: 13752.17
//
Query:       EEA18580.1  [L=572]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.5e-30  104.5  49.4    1.5e-29  103.0  44.6    2.9  2  MFS_1     Major Facilitator Superfamily
    4.5e-11   42.3  13.0    4.5e-11   42.3  13.0    2.6  3  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.0  44.6   1.7e-33   1.5e-29       2     323 ..      58     436 ..      57     450 .. 0.86
   2 ?   -0.7   0.1     0.058   5.2e+02      64     167 ..     534     548 ..     502     565 .. 0.57

  Alignments for each domain:
  == domain 1  score: 103.0 bits;  conditional E-value: 1.7e-33
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfasslwlllvlrvlqGlga 99 
                 +++a++++l+ +i++ +   a+ e +  ++  + ++ t++ lg++ a+lp++++  +f  +++++ ++l+f +g +++++ a+s+ +l+v+r ++Glg+
  EEA18580.1  58 YIGALIYGLDTTIAADIQA-AIVERFD-NVERLTWVGTAFPLGSVCAILPVSAMFHNFDLKPLFIGSILIFEVGsAVCGA-APSMNALIVGRTIAGLGG 153
                 5667777777776555555.9999999.9*********************************************666666.58888************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllgglla.sslgWravfyilaivsllafvlfllllpeepperkrkspkeee......... 188
                 +++f + + +++  ++++ergr+i+ +++ ++ Ga+lgp++gg+++ ss+ Wr++fyi+ +++++++   ++ lp  +p+ ++++++  +         
  EEA18580.1 154 SGIFLGTLNYFSLCTTEKERGRYISGIGVVWGTGAVLGPVVGGAFStSSATWRWAFYINLVIAAVCAPAYIFCLPSVKPPGAPDTSVFSRlkgldwvgf 252
                 **********************************************99999***************99777888888888888888888899******* PP

       MFS_1 189 ..................................................kgtgpaplvpawkallkdpvlwillialllfffgfsg..lltllplylq 235
                                                                        a ++p  + llkd+ l  +l+ +++++ ++++   ++++p+y  
  EEA18580.1 253 iggtgsmvsfvmaltfagsiwpwndgrtiatfvvsgvllilvllqqyfvlFTNRSARMFP-PRRLLKDKEL--ILLNIVTAAGATNIyvPVYYIPVYCS 348
                 ************************999999999998888888766666553333333333.5666666666..5555555544444445********** PP

       MFS_1 236 evlglsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllll.vlvliGfglgfvfpslla 323
                 +v+g s +l+a++ l  + ++ a + +l+g+ + r++  ++l+l++++l+++  + +++  +++++  ++  +vl+G g g++f +  +
  EEA18580.1 349 FVHGDS-ALMAAVRLLPYICFLASMNMLSGACLPRISYYWALYLFGGVLMVIGSATLYTVDIDTNMSNVYgYSVLLGAGTGLIFQAGYT 436
                 ******.8999999999999999*************************************9999999999788889**99999877665 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.058
       MFS_1  64 vlllglllfalglllllfasslwlllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsl 162
                 v                                                                                         ++i  ++++
  EEA18580.1 534 V-----------------------------------------------------------------------------------------YIISIAAGA 543
                 2.........................................................................................333333333 PP

       MFS_1 163 lafvl 167
                 + +++
  EEA18580.1 544 ITIIC 548
                 33332 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.3  13.0     5e-15   4.5e-11      47     190 ..      87     225 ..      48     230 .. 0.88
   2 !    2.0   2.1     0.008        72      65     119 ..     375     430 ..     324     433 .. 0.86
   3 ?   -4.5   0.7      0.76   6.8e+03     111     123 ..     536     548 ..     518     553 .. 0.42

  Alignments for each domain:
  == domain 1  score: 42.3 bits;  conditional E-value: 5e-15
                 HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHH CS
    Sugar_tr  47 lsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyql 145
                 +++++  +f +G+++  l ++ + + f+ k+ ++ ++++f +g+++++aa+   s+ +livgR ++G+g  ++   +  y s  +++k Rg+ +s   +
  EEA18580.1  87 RLTWVGTAFPLGSVCAILPVSAMFHNFDLKPLFIGSILIFEVGSAVCGAAP---SMNALIVGRTIAGLGGSGIFLGTLNYFSLCTTEKERGRYISGIGV 182
                 5789999********************************************...********************************************* PP

                 HHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGG CS
    Sugar_tr 146 aitfGilvaaifglglnktsnadgwrillglqlvpallllilllf 190
                  + +G +++ ++g +++++s+  +wr+ ++++lv+a + + + +f
  EEA18580.1 183 VWGTGAVLGPVVGGAFSTSSA--TWRWAFYINLVIAAVCAPAYIF 225
                 *********************..9***********9766555555 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.008
                 HHHHHHHHTTHHHHH.HHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHH CS
    Sugar_tr  65 fagllgdrfGRkksl.liaavlfvigavlqaaakgknsvevlivgRvlvGigvGla 119
                 ++g +  r+++ ++l l+++vl+vig++  ++ + ++++  ++   vl+G g Gl+
  EEA18580.1 375 LSGACLPRISYYWALyLFGGVLMVIGSATLYTVDIDTNMSNVYGYSVLLGAGTGLI 430
                 567777788888776267****************99999999999********997 PP

  == domain 3  score: -4.5 bits;  conditional E-value: 0.76
                 HHHHHHHHHHHHH CS
    Sugar_tr 111 lvGigvGlasvlv 123
                 ++ i++G++++++
  EEA18580.1 536 IISIAAGAITIIC 548
                 2222223332222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (572 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       618  (0.0344693); expected 358.6 (0.02)
Passed bias filter:                      310  (0.0172904); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.29s 00:00:00.93 Elapsed: 00:00:00.49
# Mc/sec: 3498.53
//
Query:       EEA18581.1  [L=511]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    0.00039   20.5   8.2     0.0013   18.8   8.2    1.9  1  Zn_clus      Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.052   13.9   0.3       0.11   12.8   0.3    1.6  1  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   8.2   1.4e-07    0.0013       1      34 [.      55      86 ..      55      89 .. 0.90

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 1.4e-07
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfys 34
                ++C  C+  K KC+ + P+C +C  ++ +C+ y+
  EEA18581.1 55 RSCRACSAAKAKCSFQ-PQCLRCTNKGIDCV-YD 86
                59************97.55************.76 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.3   1.3e-05      0.11       3      21 ..      22      40 ..      21      41 .. 0.95

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.3e-05
                 BBTTTTBBBSSHHHHHCCT CS
  zf-C2H2_jaz  3 YCvlCdKyFksenaldnHl 21
                 +C++CdK F +e ++  H+
   EEA18581.1 22 FCEVCDKPFLKEVSYHRHI 40
                 7*****************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (511 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       659  (0.0367561); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.71u 0.36s 00:00:01.06 Elapsed: 00:00:00.59
# Mc/sec: 2624.52
//
Query:       EEA18582.1  [L=438]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.5e-16   57.8   0.0    1.6e-15   56.9   0.0    1.3  1  Fungal_trans  Fungal specific transcription factor domain
  ------ inclusion threshold ------
      0.054   13.3   0.1        5.6    6.8   0.0    2.7  3  KNTase_C      KNTase C-terminal domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.9   0.0   1.7e-19   1.6e-15       3     176 ..      95     267 ..      94     297 .. 0.85

  Alignments for each domain:
  == domain 1  score: 56.9 bits;  conditional E-value: 1.7e-19
  Fungal_trans   3 rffsnfhpqfpilhkpsflpktssenssksayasplll..lailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsL 97 
                    +f ++h  +p+++++ f+++      + + + ++l    +++  lGa+ +++e  ++ s   +       ++l a+    +++++++s l++lq+L
    EEA18582.1  95 AYFNYVHTVIPMVNRHRFSTEL-----EMTGHRPELKSlsYSVALLGATVMSDEVDTERSFYNHA-----RSHLNAAESD-DEATDFNS-LNMLQTL 179
                   7*********************.....6666666665555***************9996666664.....4666766555.56666666.******* PP

  Fungal_trans  98 lllelyektssdralherhhgvavrlarslgLhrnpsyvgkks........lwklweeeaesrrRlwwaaFylDktialklGrpp.ll 176
                    l+ +ye+ +++ a +++ +g a rla  lgLh    ++++++           +  +e+e+rrR +w  F +D++ ++ +G  + ++
    EEA18582.1 180 ILITYYEFRRTSFARAWLSLGRANRLANMLGLHVMDQDKQSETqvdfilplPESVGLAEIEERRRSFWVLFTFDVYASIRTGSKTsIN 267
                   **************************************99888*******9667777779**********************988553 PP

>> KNTase_C  KNTase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0    0.0074        67      59     104 ..      98     143 ..      90     163 .. 0.80
   2 ?   -2.3   0.0      0.41   3.7e+03      33      58 ..     352     377 ..     351     387 .. 0.81
   3 ?    6.8   0.0   0.00062       5.6      48      77 ..     405     434 ..     382     437 .. 0.77

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.0074
    KNTase_C  59 qyaallvgLsnrklysssatvlkEaleLpdrpkgfdelvekvmegd 104
                 +y+  ++ + nr+++s+   +     eL ++  ++  l   vm+ +
  EEA18582.1  98 NYVHTVIPMVNRHRFSTELEMTGHRPELKSLSYSVALLGATVMSDE 143
                 47888999*********99999888888888777777777777666 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 0.41
    KNTase_C  33 EfigKlrnvrkegdetalatlalqlA 58 
                 E +g l+++++ gd  al+  a   A
  EEA18582.1 352 ELLGHLQPINNLGDPLALTLHATLCA 377
                 77899999999999999998887655 PP

  == domain 3  score: 6.8 bits;  conditional E-value: 0.00062
    KNTase_C  48 talatlalqlAqyaallvgLsnrklysssa 77 
                 +  +++a+q+A+ya +++ L++ k  ++++
  EEA18582.1 405 NRCTSIAMQIAEYANVISQLQDSKVCTAGQ 434
                 45689***************9999887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (438 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       356  (0.0198561); expected 358.6 (0.02)
Passed bias filter:                      302  (0.0168442); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.26s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 2831.30
//
Query:       EEA18583.1  [L=357]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    5.2e-10   39.2   0.4    1.4e-09   37.8   0.4    1.7  1  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
        1.3    8.8  13.7        2.1    8.1  13.7    1.3  1  Spore_YpjB   Sporulation protein YpjB (SpoYpjB)
        4.5    7.0  15.8          7    6.4  15.8    1.2  1  RR_TM4-6     Ryanodine Receptor TM 4-6


Domain annotation for each model (and alignments):
>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.8   0.4   2.3e-13   1.4e-09       2      60 ..      59     108 ..      58     115 .. 0.90

  Alignments for each domain:
  == domain 1  score: 37.8 bits;  conditional E-value: 2.3e-13
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh 60 
                  +e+ +aL++Wi+ql+erg p+t++++ + A+e+         + + ++k+W  r++k h
   EEA18583.1  59 KEQSRALIKWINQLTERGLPPTNSMLENFAREI---------SGKEPGKNWASRWLKAH 108
                  799******************************.........67889**********99 PP

>> Spore_YpjB  Sporulation protein YpjB (SpoYpjB)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1  13.7   0.00036       2.1       4     107 ..     224     324 ..     222     343 .. 0.86

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00036
  Spore_YpjB   4 LdqlsdevlqlvkqekleeAkqvleyfskqflsaevkereltmdelravtvtyeeavkaltsaelseeeklkavtqfrlvvDAlaskhqPLWkeleksv 102
                  +q+ d++l+   q+  e+A++  +++++q++++ +++++ +  ++r+     ++ ++a++++ l++e+ l +++q++l  D la  + P  k + k+v
  EEA18583.1 224 VQQARDNILKKDEQATQEQARKDDKKLQQQLTKQAKEQEKAERAQIRQE-KREQRLQEATEKQRLKDEQELAKLAQLQLQNDVLATPSAP--KRVTKQV 319
                 67899**********************************9*******95.567899*****************************99999..5666666 PP

  Spore_YpjB 103 mesfs 107
                  ++++
  EEA18583.1 320 SKQVK 324
                 66664 PP

>> RR_TM4-6  Ryanodine Receptor TM 4-6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4  15.8    0.0012         7      42     143 ..     200     303 ..     172     339 .. 0.57

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0012
                 XXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXX..........X CS
    RR_TM4-6  42 dllsdvfgldlkkeggqykvvakkseagLgDlseteaeespt..pelkkklaeeeeaeeekeeeeepeaeaeekadaengekeekekekeeeekeseee 138
                  +   +f + +++egg+  + + k ++   ++ ++  + +++   +  kkl+++ +++ +++e+ e+ + ++ek++++ +e++ek++ k+e+e ++ ++
  EEA18583.1 200 KEKLLLFDIPTENEGGALFMSPSKVQQARDNILKKDEQATQEqaRKDDKKLQQQLTKQAKEQEKAERAQIRQEKREQRLQEATEKQRLKDEQELAKLAQ 298
                 233345677788999999999988888888887766555554444555666666666666666666666666777777777777666655444444443 PP

                 XXXXX CS
    RR_TM4-6 139 eeekk 143
                  + ++
  EEA18583.1 299 LQLQN 303
                 33333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (357 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3334  (0.185956); expected 358.6 (0.02)
Passed bias filter:                      829  (0.0462379); expected 358.6 (0.02)
Passed Vit filter:                       177  (0.00987227); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.70u 0.28s 00:00:00.98 Elapsed: 00:00:00.43
# Mc/sec: 2507.01
//
Query:       EEA18584.1  [L=498]
Description: endoglucanase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   2.5e-143  477.9  13.4   2.5e-143  477.9  13.4    1.4  2  Glyco_hydro_7  Glycosyl hydrolase family 7
    1.6e-12   47.1  12.0    1.6e-12   47.1  12.0    4.8  4  CBM_1          Fungal cellulose binding domain


Domain annotation for each model (and alignments):
>> Glyco_hydro_7  Glycosyl hydrolase family 7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  477.9  13.4  2.8e-147  2.5e-143       5     433 ..      29     420 ..      25     421 .. 0.95
   2 ?   -4.7   0.8      0.79   7.1e+03     221     249 ..     450     476 ..     433     487 .. 0.52

  Alignments for each domain:
  == domain 1  score: 477.9 bits;  conditional E-value: 2.8e-147
                    S----EEEEEEEECTTSCEEEEEEEEEE-GGGS-EEETTSS-BSEETTEE-TTT-SSHHHHHHHEEE--HHHHHTC-EEEETTEEEEESEE.ESSS CS
  Glyco_hydro_7   5 taevhpklttqkCtkaggCkkkkgsvvldanwrwlhkvegstnCytgnkwdktlCpdeetCaknCalegadYeetygittsgdaltlklvt.keek 99 
                    t+++  +l+t+kCt++ggC ++++s+v+d  ++w+h+v+gst+C+t +  +++lC +e++C +nC +  a Y+   gi +sg+altl++++ ++ +
     EEA18584.1  29 TPDNTVSLPTWKCTSSGGCVQQSTSIVVDWVYHWIHTVNGSTSCTTSSGLNSALCGTEKECYTNCEISPATYD-GLGIRASGNALTLNQYVtSNGT 123
                    6778899******************************************************************.9************977636778 PP

                    SEEE-EEEEEEEETSTEE-EEE-TTEEEEEEEE-TT--TTEEEEEEEE---TTTTTTT-TT--SGGGGT----BTT--S--SEETTEE--TT-EEE CS
  Glyco_hydro_7 100 sknvgsrvylleedekkYemfkllnkeftfdvdvsklpCGlngalyfvemdadGgksksetnkaGakyGtGYCdaqcprdlkfingeaNvegwkps 195
                    +++v++rvyll+  +k+Yem++ll++e++fdvdvs+lpCG ngaly++emda Gg+  s+ n aGa+yG+GYCdaqc +   + ng+ N+      
     EEA18584.1 124 TNSVSPRVYLLDPAGKNYEMLQLLGQEISFDVDVSNLPCGENGALYLSEMDATGGR--SQYNPAGASYGSGYCDAQCGTGS-WFNGSINTG----- 211
                    889*****************************************************..679*****************999.99***9987..... PP

                    SSETTEEE-SEEEE--EEEEEEEESSEEEEEEE-BSSSS-EEEEGGGG-SSTTSSSB-SS-EEBETTTTT-TTSEETTSSEETTS-EEEEEEEEET CS
  Glyco_hydro_7 196 eedanagvgklGacCaemdiweaNsiataltphpcskkgqtkCegeeCggeryagvcdkdGCdfnsyrlgnkdfyGkgktvdttkkftvvtqFltd 291
                             +lG+cC+emd+weaNs+ataltphpcs +g + C+g++Cg   ++gvcdk+GC+fn+y lg++++yG+g tvdt+k+ftv tqF+t+
     EEA18584.1 212 ---------SLGSCCNEMDLWEANSQATALTPHPCSVDGPYGCSGSACG---STGVCDKNGCGFNPYALGDHNYYGSGYTVDTSKPFTVTTQFVTS 295
                    .........89*************************************6...99****************************************** PP

                    TSSTTS.EEEEEEEEEETTEEEE---.EESTTCES.SSBCHHHHHHHHHHHT-.-HHHHTTHHHHHHHHHHSEEEEEEEEEE-TTTTTHHHHSBSS CS
  Glyco_hydro_7 292 detskgelkeirrlyvqdgkviensk.skleglkkvnsitdefCeaqkkvfgdedkfkkkgglkkmgealergmvLvlsiwddkaanmlwLdskyp 386
                    d+t++g+l+eirr yvq+gkvi+n+  s+ +g++++nsit++fC++        ++  ++ggl++mgeal rgmvL++siw+d   +m+wLds   
     EEA18584.1 296 DGTKTGALTEIRRSYVQNGKVIANAVaSSSSGVSGANSITESFCTT------MDSEAGTLGGLRTMGEALGRGMVLIFSIWNDAGGSMNWLDS--- 382
                    ***********************98615677899**********97......34566789***********************99*******5... PP

                    TTS-TTSTTTB-SSS-TTTT-HHHHHHHTTT-EEEEEEEEEEETTTT CS
  Glyco_hydro_7 387 tdkdaskpgvargpCsatsgkpkevekekpdasvtfsnikvGeigst 433
                              ++gpCs+t+g+p+++++++p++svtfsnik+G+igst
     EEA18584.1 383 ---------GNSGPCSSTAGVPSTIQANDPSTSVTFSNIKWGDIGST 420
                    .........689**********************************9 PP

  == domain 2  score: -4.7 bits;  conditional E-value: 0.79
                    SEEEEEEE-BSSSS-EEEEGGGG-SSTTS CS
  Glyco_hydro_7 221 iataltphpcskkgqtkCegeeCggerya 249
                     ++a+t+   +++g t+ +  +Cgg+ y+
     EEA18584.1 450 SSSATTTT--TSTGATQTHWGQCGGTGYS 476
                    33333322..2333333344456555554 PP

>> CBM_1  Fungal cellulose binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   1.2      0.25   2.2e+03      14      25 ..      39      50 ..      37      52 .. 0.75
   2 ?    0.5   0.2      0.07   6.2e+02      11      18 ..      67      74 ..      64      81 .. 0.85
   3 ?   -1.2   2.8      0.23     2e+03       3      13 ..     196     207 ..     196     223 .. 0.70
   4 !   47.1  12.0   1.8e-16   1.6e-12       1      29 []     466     494 ..     466     494 .. 0.98

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.25
       CBM_1 14 TtCvsgatCtyq 25
                ++C+s   C++q
  EEA18584.1 39 WKCTSSGGCVQQ 50
                489998899987 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.07
       CBM_1 11 tGpTtCvs 18
                +G+T+C++
  EEA18584.1 67 NGSTSCTT 74
                69****86 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 0.23
       CBM_1   3 gQCGGigW.tGp 13 
                 +QCG  +W +G+
  EEA18584.1 196 AQCGTGSWfNGS 207
                 5***99886665 PP

  == domain 4  score: 47.1 bits;  conditional E-value: 1.8e-16
       CBM_1   1 lwgQCGGigWtGpTtCvsgatCtyqNeyY 29 
                 +wgQCGG+g++GpT+C++++tC++qN+yY
  EEA18584.1 466 HWGQCGGTGYSGPTACAPPYTCKAQNPYY 494
                 5**************************** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (498 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1024  (0.0571142); expected 358.6 (0.02)
Passed bias filter:                      429  (0.0239277); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.29s 00:00:00.93 Elapsed: 00:00:00.45
# Mc/sec: 3324.08
//
Query:       EEA18585.1  [L=458]
Description: hypothetical protein PMAA_008730 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (458 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       584  (0.0325729); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.56u 0.30s 00:00:00.86 Elapsed: 00:00:00.48
# Mc/sec: 2848.59
//
Query:       EEA18586.1  [L=82]
Description: hypothetical protein PMAA_008740 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (82 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       588  (0.032796); expected 358.6 (0.02)
Passed bias filter:                      447  (0.0249317); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.39u 0.26s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 582.29
//
Query:       EEA18587.1  [L=608]
Description: translation initiation factor eIF-2B subunit family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.7e-18   65.1   0.0    5.3e-17   61.9   0.0    2.1  2  IF-2B     Initiation factor 2 subunit family
    4.8e-07   29.9   0.0      1e-06   28.8   0.0    1.5  1  NUDIX     NUDIX domain


Domain annotation for each model (and alignments):
>> IF-2B  Initiation factor 2 subunit family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0      0.04   3.6e+02      12      54 ..     242     284 ..     235     299 .. 0.81
   2 !   61.9   0.0   5.9e-21   5.3e-17     107     280 ..     379     585 ..     337     587 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.04
                 HHHHHHHHHHHCCCSTHHHH.HHHHHHHHHHHHTSSTS-HHHHH CS
       IF-2B  12 alevllevikdaktskvaeL.keelrkaidlLkkarPtavslgn 54 
                 + e+l++  +d++ s ++eL +  l+   d L++ rP+ v + +
  EEA18587.1 242 LREGLQQLQNDHE-SGARELaTIALSILKDILIEVRPSTVRVES 284
                 5567777777777.888888788999999*********999876 PP

  == domain 2  score: 61.9 bits;  conditional E-value: 5.9e-21
                 TTEEEEEES--SHHHHHHHHHHHTT......EEEEEEEEEXTTTTHH.HTHH..........HHHHHTTXEEEEEEGGGHHHHHHCTESEEEEEXSEEE CS
       IF-2B 107 dgdtilTicnsktvlevlraaakek......kkfkVivvEsrPrlqG.rlta..........keLvqagipvtlitdsavayvmseevdkvivGAdril 188
                 +  +++T + s+t+ e + +  +++       ++    +EsrP  +G  l            k +++ +i++tl td ++a   +  vd v++GAdri+
  EEA18587.1 379 KTLRVMTLSASSTIRESILHFLSSGvcdfsfETLDLRILESRPLYEGvSLASiilssykslgKDVTRPKINITLYTDCSAALAARD-VDVVLIGADRIA 476
                 55689********999999988888899999999999**********7665422222222223445679***********999999.***********9 PP

                 T.TSEEEEETTHHHHHHHHHHT..TXEEEEEXXGGGBESTSSSGGGSSXXBEXTHHHHEETTEESSTT...............TEEEEEBSEEEEEGGG CS
       IF-2B 189 e.nGaiankiGTsslAvlAkef..nipvlvvaeslkfservqldedifieerdpeellnitgeriaee...............elkvvnpafDvtPpel 269
                   +Ga++nk+G++   ++Ak+   + ++lv+ e+ k+ +  ++d+    e +d +e+l+      ++                 l+v n  f  +P+ l
  EEA18587.1 477 GlDGAVSNKTGSLPAILAAKHLspQAKILVISELDKVAQVESMDSHAE-EDNDVAEVLCAWRLAGVKGagvidsqlsgeqnddALAVKNVYFEWVPAAL 574
                 559***********9999999633689************988888555.9999999999877666665899999************************* PP

                 XSEEEETTEEE CS
       IF-2B 270 ItliITevGvl 280
                 I+ +IT++Gv+
  EEA18587.1 575 IDSYITDEGVM 585
                 *********98 PP

>> NUDIX  NUDIX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.8   0.0   1.2e-10     1e-06      15     117 ..      77     200 ..      59     211 .. 0.64

  Alignments for each domain:
  == domain 1  score: 28.8 bits;  conditional E-value: 1.2e-10
                 SEEEEEEES...SSSTTTEESSEEECBT..TSHHHHHHHHHHHHHHSEEEEEEEEEEEEEEEEEEEEEEEE..EEEEEEEEE......EEECSGCSST. CS
       NUDIX  15 gevLlvrrs...kkpfpgWelPgGkvep..gEtpeeAArREleEEtGleaellellgrlhylapydgpygd..eheilyvfl......eevegelepn. 99 
                 ++v l rrs    +++++ + ++G ++p  + tp e+A REl+EEt l+  +++ + +    + + +++++  +++ +y f+       + ++ l+p  
  EEA18587.1  77 TKVALFRRSdkvHTYPRHLAPIAGAIDPqtDATPVETAWRELKEETSLTSSTVKPWRK---GRVFSFKDESvgREWTIYPFAfllkspSDRTEALQPAe 172
                 3499*****7644444447899*****96444****************8877777663...33333333335578888666555765433444444447 PP

                 ...........STTTEEEEEEEEHHHHHH CS
       NUDIX 100 ...........denevsevrwvpleellk 117
                             + e++ + w++++e+ +
  EEA18587.1 173 ncdnddgdgitLDWEHDFYNWHDPDEV-L 200
                 766654444444555777779999999.3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (608 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       415  (0.0231469); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.31s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 3967.82
//
Query:       EEA18588.1  [L=110]
Description: hypothetical protein PMAA_008760 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (110 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       435  (0.0242624); expected 358.6 (0.02)
Passed bias filter:                      315  (0.0175693); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.45
# Mc/sec: 726.98
//
Query:       EEA18589.1  [L=96]
Description: hypothetical protein PMAA_008770 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (96 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       486  (0.0271069); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.39u 0.28s 00:00:00.67 Elapsed: 00:00:00.43
# Mc/sec: 677.96
//
Query:       EEA18590.1  [L=443]
Description: hypothetical protein PMAA_008780 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (443 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       724  (0.0403815); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.51
# Mc/sec: 2608.71
//
Query:       EEA18591.1  [L=503]
Description: hypothetical protein PMAA_008790 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.8e-05   24.9   0.0    7.9e-05   22.8   0.0    2.0  2  rve            Integrase core domain
    0.00072   19.7   0.2      0.015   15.6   0.0    2.8  2  Clr5           Clr5 domain
     0.0021   18.2   3.1      0.077   13.3   0.3    2.5  2  HTH_Tnp_Tc3_2  Transposase
  ------ inclusion threshold ------
      0.015   15.1   0.9       0.12   12.1   0.3    2.8  2  Arg_repressor  Arginine repressor, DNA binding domain
      0.051   13.2   0.5       0.44   10.2   0.1    2.4  2  HTH_33         Winged helix-turn helix
      0.078   12.4   1.2       0.14   11.6   1.2    1.3  1  HMMR_N         Hyaluronan mediated motility receptor N-termin
       0.17   11.9   0.2        7.7    6.5   0.1    2.8  3  HU-DNA_bdg     DNA-binding domain


Domain annotation for each model (and alignments):
>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0      0.96   2.5e+03      67      97 ..      30      61 ..      13      70 .. 0.72
   2 !   22.8   0.0   3.1e-08   7.9e-05       2      79 ..     192     266 ..     191     283 .. 0.76

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.96
         rve 67 pervlsDngseytsk..afrefladlgirvsft 97
                + ++lsD+  ++t +  ++r+ l+++g++ +++
  EEA18591.1 30 ITKILSDKY-QITVHsqTIRRRLQQWGVSRTNH 61
                677888876.44444459999999999987766 PP

  == domain 2  score: 22.8 bits;  conditional E-value: 3.1e-08
         rve   2 trpgelwqvDvt.vvripdgggkayllvvvddfsrlilaealsdemdastvlalleravarfggve..pervlsDngseyt 79 
                 + p+++w++D   +++   +g  + +++++d+fsr+i+ +++  +  + t + +l+++++ +++ +  p++++sD+g e +
  EEA18591.1 192 PGPNYIWSMDGHdKLS--FWG--IQIYAAIDAFSRYITWCYVGIS--NRTQISVLRQFLEVLQETKiqPRYIRSDKGGETV 266
                 579*******985555..678..99*************9998765..444455555555555554455*********9876 PP

>> Clr5  Clr5 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   5.7e-06     0.015       2      52 ..       7      56 ..       6      58 .. 0.92
   2 ?    0.6   0.1      0.26   6.6e+02       9      33 ..      67      91 ..      60     106 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 5.7e-06
        Clr5  2 eedWeahkatIrrLYleenrsLkdvmeiMeeehgFkatkrqyktrfkkWgf 52
                + d +++k++I + +l+   s +++ +i+ ++++ +   +  ++r+++Wg+
  EEA18591.1  7 PSDIDQYKEEISSSFLNG-QSASNITKILSDKYQITVHSQTIRRRLQQWGV 56
                57889**********865.79****************************97 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.26
        Clr5  9 katIrrLYleenrsLkdvmeiMeee 33
                 + I++LY +++   ++++  +e++
  EEA18591.1 67 EDKIKELYFQHGLRDRQIIHALEKN 91
                68899***99988888888888764 PP

>> HTH_Tnp_Tc3_2  Transposase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.3   0.3     3e-05     0.077      15      48 ..      26      60 ..      24      66 .. 0.86
   2 ?    4.7   0.2     0.014        35      17      48 ..      82     113 ..      81     116 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 3e-05
  HTH_Tnp_Tc3_2 15 tlreLanelkee.GksvsreTirrrLrkaglkkrk 48
                   ++ ++++ l+++  ++v+++TirrrL++ g + ++
     EEA18591.1 26 SASNITKILSDKyQITVHSQTIRRRLQQWGVSRTN 60
                   7788999999999**************99987665 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.014
  HTH_Tnp_Tc3_2  17 reLanelkeeGksvsreTirrrLrkaglkkrk 48 
                    r+++  l+++G+++s++T   + r+ gl+ r+
     EEA18591.1  82 RQIIHALEKNGIKISQSTLTTIRRRLGLHRRV 113
                    5788889778*****99877776777777665 PP

>> Arg_repressor  Arginine repressor, DNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.1      0.43   1.1e+03      31      59 ..      37      65 ..      25      71 .. 0.75
   2 ?   12.1   0.3   4.7e-05      0.12       9      43 ..      69     102 ..      62     117 .. 0.73

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.43
                   TTT----HHHHHHHHHHHT-EEEETTSTS CS
  Arg_repressor 31 eeGidvtQatvSRdLkelglvkvraenge 59
                   ++ i v   t+ R L+  g+ +++ e++e
     EEA18591.1 37 KYQITVHSQTIRRRLQQWGVSRTNHESKE 65
                   56788888899999999999999877765 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 4.7e-05
                    HHHHHHHHS---SHHHHHHHHHTTT----HHHHHH CS
  Arg_repressor   9 likkiikeekissQkelvelLkeeGidvtQatvSR 43 
                    +ik++  ++ ++   +++ +L+++Gi++ Q+t+  
     EEA18591.1  69 KIKELYFQHGLRD-RQIIHALEKNGIKISQSTLTT 102
                    5555555555543.69****************975 PP

>> HTH_33  Winged helix-turn helix
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.1   0.00017      0.44       9      37 ..      29      57 ..      26      59 .. 0.90
   2 ?   -0.0   0.0      0.27   6.9e+02      17      37 ..      90     110 ..      82     116 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00017
      HTH_33  9 rlaqlieerfgvsysvsgvyrlLkrlGfs 37
                 +++ + +++++++++++++r L+ +G s
  EEA18591.1 29 NITKILSDKYQITVHSQTIRRRLQQWGVS 57
                5888999********************88 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 0.27
      HTH_33  17 rfgvsysvsgvyrlLkrlGfs 37 
                 + g+++s+s+++ + +rlG+ 
  EEA18591.1  90 KNGIKISQSTLTTIRRRLGLH 110
                 449***********9999986 PP

>> HMMR_N  Hyaluronan mediated motility receptor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   1.2   5.3e-05      0.14      53     129 ..      36     113 ..      11     133 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 5.3e-05
      HMMR_N  53 rkvsvlelkkaksqkkdkskltkekkkqkeLEkeiRsLvqergeqdkrl.qaleeelkkveakLlaavrektslsanv 129
                  k+++    ++   + ++ ++++ + + keLE  i++L  + g +d+++ +ale++  k++   l+ +r ++ l   v
  EEA18591.1  36 DKYQITVHSQTIRRRLQQWGVSRTNHESKELEDKIKELYFQHGLRDRQIiHALEKNGIKISQSTLTTIRRRLGLHRRV 113
                 45555555554455555678899999**********************64799***9999999999999999987665 PP

>> HU-DNA_bdg  DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.1     0.003       7.7      14      53 ..      64     103 ..      57     109 .. 0.88
   2 ?    1.7   0.0     0.095   2.4e+02      42      69 ..     111     138 ..     105     146 .. 0.90
   3 ?   -2.2   0.0       1.6     4e+03      17      39 ..     316     338 ..     315     361 .. 0.74

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.003
                 -----EEEEE----EE-HHHHHHHHHHH-TTS-HHHHHHH CS
  HU-DNA_bdg  14 dkksdyiaqvessgsltledIidemvkegtevrketieni 53 
                 ++ +d+i ++ ++  l+  +Ii ++ k+g ++++ t+++i
  EEA18591.1  64 KELEDKIKELYFQHGLRDRQIIHALEKNGIKISQSTLTTI 103
                 566899*******************************988 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.095
                 -TTS-HHHHHHHHHHHHHHHHHHHTTT- CS
  HU-DNA_bdg  42 gtevrketienilnlykrevseaileGy 69 
                 +  v++e+i+ni +l+  ev +++ +G+
  EEA18591.1 111 RRVVNPEDIQNINDLVRAEVQKQLNSGR 138
                 56799******************99996 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 1.6
                 --EEEEE----EE-HHHHHHHHH CS
  HU-DNA_bdg  17 sdyiaqvessgsltledIidemv 39 
                 +dy +++ + g ++ + ++d+++
  EEA18591.1 316 RDYFLKLSNDGYFKKNSLADRIA 338
                 58999999999999999999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (503 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       861  (0.0480228); expected 358.6 (0.02)
Passed bias filter:                      588  (0.032796); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.62u 0.31s 00:00:00.93 Elapsed: 00:00:00.47
# Mc/sec: 3212.43
//
Query:       EEA18592.1  [L=368]
Description: hypothetical protein PMAA_008800 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
  ------ inclusion threshold ------
      0.054   13.8   0.1       0.12   12.7   0.1    1.5  1  Mur_ligase  Mur ligase family, catalytic domain


Domain annotation for each model (and alignments):
>> Mur_ligase  Mur ligase family, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.1   6.6e-06      0.12      21      74 ..      32      78 ..      25      85 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 6.6e-06
                HTTSEEEEEESSHCHHHTT-EEEES-HGGGGEE-TS-TTCHHHHHHHHTTEEEE CS
  Mur_ligase 21 lkGykvdGsdfieslialGaaavvghdaanivvssiskdnpeleaakepgipve 74
                +  ++v G++ ++ l+a+Ga  ++ ++++       ++dn+ + +ak++ +   
  EEA18592.1 32 DNTHTVRGRQRKQALEAKGALYAQLDREK-------RNDNQAINRAKKRLVDST 78
                6789*************************.......999********9988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (368 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       779  (0.0434492); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.40
# Mc/sec: 2785.42
//
Query:       EEA18593.1  [L=146]
Description: histone H3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-35  122.6   0.4    1.6e-35  122.3   0.4    1.1  1  Histone   Core histone H2A/H2B/H3/H4
    0.00058   20.0   0.2    0.00086   19.4   0.2    1.2  1  CENP-T_C  Centromere kinetochore component CENP-T histone fol
     0.0058   17.0   0.6     0.0095   16.3   0.6    1.3  1  CENP-S    CENP-S protein


Domain annotation for each model (and alignments):
>> Histone  Core histone H2A/H2B/H3/H4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  122.3   0.4   2.7e-39   1.6e-35       1     129 [.       1     130 [.       1     132 [. 0.93

  Alignments for each domain:
  == domain 1  score: 122.3 bits;  conditional E-value: 2.7e-39
                 XXEESXEEEXXXXEEXXXXXXXXXXHT.TS-SSSSB--TTT-XTTHHHHHHHHHHHHXXSXXSXHHHHHHHHHHHH...TTSSSXEEXHHHHHHHHHHH CS
     Histone   1 marekekarkesektapekkvsakker.kasskskkkkkrryrpgtvalkeirkyqkstdlliqklpfaRvvreivk..sekedlrisaeavlalqeal 96 
                 mar+k++ark  +++ p+k++  + +r      + ++++rry+ gt al+eir+yqkstdl i+klpf+R+vrei    + ++d+r++++a+lalqea+
  EEA18593.1   1 MARTKMPARKIAQGKGPRKTLPGAGKRvLP--PPPPRRRRRYKWGTTALREIRRYQKSTDLIIPKLPFQRLVREIAHqvTLEKDMRWQKSAILALQEAA 97 
                 99***************9999999877422..3678999************************************999********************* PP

                 HHHHHHHHHHHHHHHHHTTXSEEXHHHHHHHHH CS
     Histone  97 EallvelfeeAnllakhaKRvTitpkDiqlArr 129
                 Ea+lv  fe++nl+a+ha+RvTi++kD+ql+ +
  EEA18593.1  98 EAFLVKEFEMTNLAAIHAHRVTIQSKDMQLVDQ 130
                 *****************************9855 PP

>> CENP-T_C  Centromere kinetochore component CENP-T histone fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.2   1.4e-07   0.00086       6      78 ..      62     133 ..      55     142 .. 0.81

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 1.4e-07
    CENP-T_C   6 pslP.aavvkklakrfakasgskaklekealkalekasdkffeqvgeDLeayakHagRKtidesDvilLmkrqr 78 
                 p+lP + +v+ +a++++ +  + ++ +k+a+ al++a + f+ +  e  +  a Ha R ti+++D+ l  + +r
  EEA18593.1  62 PKLPfQRLVREIAHQVTLE--KDMRWQKSAILALQEAAEAFLVKEFEMTNLAAIHAHRVTIQSKDMQLVDQLRR 133
                 6666334677788887655..99*********************9999999999***********987654444 PP

>> CENP-S  CENP-S protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.6   1.6e-06    0.0095       9      69 ..      68     128 ..      63     134 .. 0.91

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 1.6e-06
      CENP-S   9 ysvgkiveeeaaekeveatkqfiaaltelvykqlenlakDLeaFakHAkRstittdDvlLl 69 
                   v++i ++ ++ek+++  k++i al e   + l +  +  ++ a HA R ti+ +D+ L+
  EEA18593.1  68 RLVREIAHQVTLEKDMRWQKSAILALQEAAEAFLVKEFEMTNLAAIHAHRVTIQSKDMQLV 128
                 67999999**********************999999989999999*************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (146 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       585  (0.0326287); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.42u 0.24s 00:00:00.65 Elapsed: 00:00:00.40
# Mc/sec: 1085.27
//
Query:       EEA18594.1  [L=383]
Description: branched-chain amino acid aminotransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.3e-25   90.6   0.0    1.6e-25   90.3   0.0    1.1  1  Aminotran_4     Amino-transferase class IV
  ------ inclusion threshold ------
        0.1   13.1   0.0       0.19   12.2   0.0    1.4  1  Ribosomal_L9_C  Ribosomal protein L9, C-terminal domain


Domain annotation for each model (and alignments):
>> Aminotran_4  Amino-transferase class IV
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.3   0.0   1.8e-29   1.6e-25       1     223 []      67     312 ..      67     312 .. 0.88

  Alignments for each domain:
  == domain 1  score: 90.3 bits;  conditional E-value: 1.8e-29
  Aminotran_4   1 glfEtmrvy....ngei..ffldeHleRLrksaellglelpfdeeelrkileelleannsen........grlrllvsrgggglg.aatsepsvavyv 83 
                  +++E+m++     n+ +  f+ ++++ R+++sa+ +  +++++ee+++k ++ +++an +++         ++r+l+++ g++lg ++  e++++v+v
   EEA18594.1  67 QAYEGMKAFrspdNKTVtiFRPNRNAIRMQHSADFV-SMPRIPEEHFMKCVNLAVAANAEFVpphetgaaMYIRPLMFGSGAQLGlNPPDEYTFVVFV 163
                  579999988888644436599***************.99****************************99888*************5555555555555 PP

  Aminotran_4  84 salppgpeseke.lplvtssdvrrdapsplpgaKtln.yldnvlarreakergadevllvdedgn..vtEgstsNv.fivk......ggelitPplss 170
                    +p g +  ++ + + +  d  r+ap  +  aK    y++ ++  ++a ++++  +l +d++ +  + E+sts +  ++k      + ++++P+ ++
   EEA18594.1 164 --MPTGVYHGVHaVDALILEDFDRSAPEGTGSAKVGGnYAPVLRHSQRAYAEKYGITLHLDSKTRseIDEFSTSAFiGVRKnpvdkdDVTIVVPDSKN 259
                  ..555666666665788888899999999999998766*************************9999*********66666*****777777777655 PP

  Aminotran_4 171 giLpGitrrallelakal.gleveereitlkdleeadeafltntlrgvlpvrsi 223
                   +++++t +++ ela ++ g +ve+r+i +++++e+de+f  +t++ ++p++si
   EEA18594.1 260 -VIDSVTAASVYELASKAlGYKVEKRRIPYEEIREFDEVFAAGTAAALVPIKSI 312
                  .**************9999*********************************98 PP

>> Ribosomal_L9_C  Ribosomal protein L9, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   2.1e-05      0.19      24      63 ..     256     294 ..     242     300 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2.1e-05
                     TT-BBSS---HHHHHHHHHHHT-----GGGEE-TTT-SBS CS
  Ribosomal_L9_C  24 edgklFGsVtakdIaealkkklgieidkkkieleepiktl 63 
                     +++++  sVta+ + e  +k+lg++++k++i  ee i+++
      EEA18594.1 256 DSKNVIDSVTAASVYELASKALGYKVEKRRIPYEE-IREF 294
                     5566788************************9854.7766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (383 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       371  (0.0206927); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 2615.80
//
Query:       EEA18595.1  [L=1181]
Description: protein kinase and ribonuclease Ire1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.3e-39  135.3   0.1    2.4e-39  134.4   0.1    1.5  1  Ribonuc_2-5A    Ribonuclease 2-5A
    3.7e-39  134.7   0.0    3.7e-28   98.6   0.0    2.3  2  Pkinase         Protein kinase domain
    7.3e-20   71.3   0.0    9.3e-19   67.7   0.0    2.1  1  Pkinase_Tyr     Protein tyrosine kinase
    3.2e-05   23.6   0.0       0.12   12.3   0.0    3.0  2  PQQ             PQQ enzyme repeat
     0.0048   16.5   0.1      0.027   14.1   0.1    2.1  2  PQQ_2           PQQ-like domain
  ------ inclusion threshold ------
      0.012   15.0   0.0      0.027   13.8   0.0    1.5  1  Kdo             Lipopolysaccharide kinase (Kdo/WaaP) family
      0.048   12.4   0.0       0.11   11.2   0.0    1.5  1  Pkinase_fungal  Fungal protein kinase
       0.16   12.1   0.0       0.44   10.7   0.0    1.7  1  Pcc1            Transcription factor Pcc1


Domain annotation for each model (and alignments):
>> Ribonuc_2-5A  Ribonuclease 2-5A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  134.4   0.1   1.1e-42   2.4e-39       1     127 []    1048    1177 ..    1048    1177 .. 0.96

  Alignments for each domain:
  == domain 1  score: 134.4 bits;  conditional E-value: 1.1e-42
  Ribonuc_2-5A    1 rlefLrdvSdrfeiekrdpesellkkLeseasevvks..dWtkkldkelvdslgkyrkYkgdsvrdLLRaiRNkkeHyeelpedvkeilgelpeg 93  
                    rl+fL+dvSd+fe+e+rdp+s +l+ Les a++v++   d+ k l ke+ dslgk+rkY+g++++dLLRa+RNk++Hy++++e++k+++g lpeg
    EEA18595.1 1048 RLNFLCDVSDHFEFEPRDPPSLALQYLESVARNVMGPdmDFLKLLPKEFKDSLGKQRKYTGSRMLDLLRALRNKRNHYNDMSEHLKAHIGGLPEG 1142
                    79********************************87778******************************************************** PP

  Ribonuc_2-5A   94 flsYftkrFPkLlievyevvketl.keeevfkkyf 127 
                    +l++++ rFP+Ll+++++vv e    + e+fk+yf
    EEA18595.1 1143 YLRFWAVRFPSLLMNCHRVVVELDlCRLERFKRYF 1177
                    ********************999878888888886 PP

>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.6   0.0   1.6e-31   3.7e-28       5     176 ..     745     931 ..     741     938 .. 0.86
   2 !   33.8   0.0     1e-11   2.3e-08     168     264 .]     950    1042 ..     945    1042 .. 0.74

  Alignments for each domain:
  == domain 1  score: 98.6 bits;  conditional E-value: 1.6e-31
                 EEEEEESSEE.EEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHS.CTTB--EEEEEEESSEEEEEEE--TTEBHHHHHHHHSS--HH... CS
     Pkinase   5 eklGeGsfGk.VykaveketgkivAvKkikkekakkkkekkvlrEikilkklk.hpnivrlyevfeekdelylvleyveggeladllerkgslsee... 98 
                 + lG+Gs G+ Vyk+    +g+ vAvK++ +e  +  ++     E+ +l++++ h+n++r+y   +    ly+ le+++  +l++++e+ + +++    
  EEA18595.1 745 TVLGHGSHGTiVYKGS--FDGRDVAVKRMLVEFFDIASH-----EVGLLQESDdHSNVIRYYCREQAVGFLYIALELCP-ASLQEVVEKPQDYPQLvkg 835
                 689******9457877..8************98887665.....***********************************.55*****954444444555 PP

                 ..HHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEE.TTTE..........EEE-SGTTSEESSSSCS.....BCTTTSCGGGS-HHHHTTSCBSH CS
     Pkinase  99 ..eakkiakqilegleylHskgiiHrDlKpeNiLid.ekge..........lKitDFGlakelesssk.....ltsfvgtseYlAPEvlkeneysk 176
                   ++ +i++qi  g++ylHs +i+HrDlKp+NiL+   +g           l i+DFGl+k+le +++     + +  gts ++APE+l +++ ++
  EEA18595.1 836 glDVPDILRQITLGVRYLHSLKIVHRDLKPQNILVAaPRGRsmssqypalrLLISDFGLCKKLEDNQSsfratTAHAAGTSGWRAPELLVDEDQQS 931
                 66999*******************************55444667778888899************9999**99999*************5554444 PP

  == domain 2  score: 33.8 bits;  conditional E-value: 1e-11
                  HH...TTSCBSHHHHHHHHHHHHHHHHH.SS-STTTSSHHHHHHHHHHTHHHHHHHCT..SHH...HHHTTS-HHHHHHHHHHT-SSGCCSTTHHHH CS
     Pkinase  168 vl...keneyskkvDvWslGvilyellt.gkppfsgekgkekvekeldqlekilkilg..etkeklpeaseiseeakdllkkllkkdpkkRltaeel 258 
                  v+   ++++ ++++D++slG+++y +lt g +p+    ++ k+   +++    ++i++   + e+l++  +   ea dl++++l+ +p++R+ a+ +
  EEA18595.1  950 VVdpqTNRRATRAIDIFSLGCVFYYVLTrGGHPYD---KDGKF---MRE----ANIVKgnYNLEELERLGDYAFEADDLIRSMLSLNPRSRPDATTV 1036
                  55553345569************998873678898...33322...222....2222222455678888888************************* PP

                  HTSGGG CS
     Pkinase  259 lqhpyl 264 
                  l hp++
  EEA18595.1 1037 LMHPFF 1042
                  *****8 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.7   0.0   4.1e-22   9.3e-19       4     255 ..     744    1036 ..     741    1039 .. 0.84

  Alignments for each domain:
  == domain 1  score: 67.7 bits;  conditional E-value: 4.1e-22
                   EEEEEEESSEE.EEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS.-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHTCT CS
  Pkinase_Tyr    4 gkklGeGafGk.VvegtlkgekekkevkVavKtlkeeateeekeelleeakimkkl.khpnivkllgvctkeepllivteyvkgGdLlkfLrkkek 97  
                   ++ lG+G+ G+ V++g+ +        +VavK +  e  +       +e+ ++++  +h n+++++      + l+i +e+++  +L++ ++k ++
   EEA18595.1  744 DTVLGHGSHGTiVYKGSFD------GRDVAVKRMLVEFFDI----ASHEVGLLQESdDHSNVIRYYCREQAVGFLYIALELCPA-SLQEVVEKPQD 828 
                   5789*****9835677777......99*****995555444....578******************99999999********96.8******9966 PP

                   TTSBHH...HHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEE...........TTEEEE-STTTHEETTTSSEE..EETTSSTSGGGGS-HHHH CS
  Pkinase_Tyr   98 ekltlk...dllsfalqvAkGmeyLeskklvHrdlaarNvLlse...........nkvvkisDfGLardiekddey..vkkeeaklpvkWmapEsl 177 
                    +  +k   d+ ++  q+  G++yL+s k+vHrdl  +N+L++                 isDfGL++++e++++    ++ +a     W apE l
   EEA18595.1  829 YPQLVKgglDVPDILRQITLGVRYLHSLKIVHRDLKPQNILVAAprgrsmssqypALRLLISDFGLCKKLEDNQSSfrATTAHAAGTSGWRAPELL 924 
                   555555222566899****************************999*****99988899***********7766665456667778999******* PP

                   HHSE..............................EEHHHHHHHHHHHHHHHHTTSSGTTTTS.HHHHHHHHHHTTEES-BBT...TSBHHHHHHHH CS
  Pkinase_Tyr  178 kekk..............................ftsksDvWsfGvllwEiftlgespypgl.kneevleklkegkrlekpe...kcpeelyelmk 239 
                    ++                                t + D++s G + + ++t g +py +  k ++ ++ +k +++le+ e   +   e  +l++
   EEA18595.1  925 VDEDqqsaiainsghsnhtessepavvdpqtnrrATRAIDIFSLGCVFYYVLTRGGHPYDKDgKFMREANIVKGNYNLEELErlgDYAFEADDLIR 1020
                   9988899**************************999***********************9864555556666777776666511155667889999 PP

                   HHT-SSGGGS--HHHH CS
  Pkinase_Tyr  240 kcweedpeeRptfsel 255 
                   + ++ +p++Rp+ +++
   EEA18595.1 1021 SMLSLNPRSRPDATTV 1036
                   99999****9997766 PP

>> PQQ  PQQ enzyme repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.3   0.0   5.4e-05      0.12       4      28 ..     131     155 ..     130     159 .. 0.85
   2 !    8.0   0.0    0.0013       2.9       7      26 ..     235     254 ..     229     263 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 5.4e-05
                 EEEETTSEEEEEETTTCCEEEEEES CS
         PQQ   4 ylgsadGylyAlDadTGkvlWrfkt 28 
                  l++ dG++ A D++TG  +W  ++
  EEA18595.1 131 LLATVDGTIHARDRKTGSPRWALEV 155
                 46799****************8666 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0013
                 ETTSEEEEEETTTCCEEEEE CS
         PQQ   7 sadGylyAlDadTGkvlWrf 26 
                  + ++ly +Da+TG+vl +f
  EEA18595.1 235 RKETTLYTVDARTGNVLRVF 254
                 67789***********9666 PP

>> PQQ_2  PQQ-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.1   0.1   1.2e-05     0.027     122     234 ..     127     251 ..      97     254 .. 0.56
   2 ?    1.0   0.0      0.12   2.6e+02      37      69 ..     229     261 ..     178     283 .. 0.69

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 1.2e-05
       PQQ_2 122 gdtvvvgessgklvaldpkdGkvlWerel.aaprgtsels...rvgdisgrpvvaegtVyassgqgr..llal.dlatgr..rl.w.ske.issinglp 208
                  d v++++ +g ++a+d k+G+++W  e+ ++p  +s ++    +g  +g+ + +++ + +++ ++   l  +   ++g   +l    k+ +++ +   
  EEA18595.1 127 EDFVLLATVDGTIHARDRKTGSPRWALEVpSSPMVESIYHnrsTTGFDTGSSIRDDDFLWIVEPSKDgsLYIFsPGRQGGlqKLgLtVKDlVNE-TP-Y 223
                 5677788888888999999999999999988888888777765555555666666555555543332225555555555533111112221111.22.2 PP

       PQQ_2 209 ildgdllyvvsa..gelialdratGavl 234
                   ++  + ++ +  ++l+ +d  tG+vl
  EEA18595.1 224 SGTDPAVTYTARkeTTLYTVDARTGNVL 251
                 3333333333323677777777777765 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.12
       PQQ_2  37 gtlfvatgggrlvaldaatGkvlWettlegpvv 69 
                  + ++a ++ +l+ +da tG vl  ++ +gp+ 
  EEA18595.1 229 AVTYTARKETTLYTVDARTGNVLRVFSSRGPLS 261
                 456666777777777777777776666666655 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   1.2e-05     0.027     122     155 ..     841     874 ..     817     887 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.2e-05
         Kdo 122 allkavgrliaklhragvnHadlyaknillqqee 155
                  +l+++   ++ lh++++ H+dl ++nil+ +  
  EEA18595.1 841 DILRQITLGVRYLHSLKIVHRDLKPQNILVAAPR 874
                 5799**************************8875 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   4.9e-05      0.11     314     386 ..     845     924 ..     840     944 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 4.9e-05
  Pkinase_fungal 314 DaIkghrsLflkagiLHrDiSenNilitdskke......gerkglLiDLDlakelsddssesga..rertGTleFmaievl 386
                     +   g r L+   +i+HrD   +Nil+  ++        +  + l++D+ l k+l+d++s+  a   +  GT  + a e+l
      EEA18595.1 845 QITLGVRYLH-SLKIVHRDLKPQNILVAAPRGRsmssqyPALRLLISDFGLCKKLEDNQSSFRAttAHAAGTSGWRAPELL 924
                     5566889999.9****************664445666678889999**********8655543344788888776666665 PP

>> Pcc1  Transcription factor Pcc1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00019      0.44       4      39 ..     604     638 ..     602     667 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00019
                 EEEE-SSHHHHHHHHHHHHHHCHC-TTECEEEEEEE CS
        Pcc1   4 isvpfpterlAsialrtLqvDkelsplavkrslsle 39 
                 i+ +f t+r+As+ l+ LqvD+e  p   +r  sl+
  EEA18595.1 604 IRSEFTTPRKASVQLEDLQVDNESTPR-NERASSLS 638
                 7889*******************9998.66666664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       461  (0.0257125); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.79u 0.29s 00:00:01.08 Elapsed: 00:00:00.44
# Mc/sec: 8051.62
//
Query:       EEA18596.1  [L=484]
Description: CCCH zinc finger domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (484 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       581  (0.0324056); expected 358.6 (0.02)
Passed bias filter:                      416  (0.0232026); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 3213.07
//
Query:       EEA18597.1  [L=309]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.8e-64  216.1   2.2    7.1e-64  215.8   2.2    1.1  1  ELYS      Nuclear pore complex assembly


Domain annotation for each model (and alignments):
>> ELYS  Nuclear pore complex assembly
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  215.8   2.2     4e-68   7.1e-64       1     219 [.      37     253 ..      37     254 .. 0.97

  Alignments for each domain:
  == domain 1  score: 215.8 bits;  conditional E-value: 4e-68
        ELYS   1 kLFiDrllsalaiqkdsgeaaklYPPkslqalrdlllqigsssevdllaKqslllYlLlDldasseeselaedFaaafglprklvllvqglwlLDhgef 99 
                 +LFiDrll + ++++    ++++YPPks+q lr+l++qi+  s++ +++Kq++++YlL D++a    +e++ +F +++++p k++l+++glw+LD+ ef
  EEA18597.1  37 RLFIDRLLGLTGVKA----VHEKYPPKSNQHLRELYKQILL-SSFPNHQKQAVIYYLLRDCRA----NEALAQFLRRCSIPDKYQLFIDGLWHLDRLEF 126
                 59*******666999....99********************.78****************976....69****************************** PP

        ELYS 100 eealelLtdPslspkefadkilqvLler....gdaslalaylravkpplssseavealfvllargsvteAfsfqRslsdkekreelleelvelclee.. 192
                   al++Lt+Psl+p +f+d+il+ L+      +d+sla+ay+ +v+ppl+s++++  +f++l+r s+teAf+f R+++d+ +r+++le+l+ +++++  
  EEA18597.1 127 PLALQYLTEPSLIP-TFPDEILYILTLPklpkHDDSLAIAYYLTVSPPLDSEKVQSSYFETLCRASITEAFYFLRKYDDS-RRRQFLEQLILFVHKTpt 223
                 *************9.************9***************************************************9.****************** PP

        ELYS 193 ...aarklkeLlelpldeeEekllekfLls 219
                    + +++ eLl+lp+d+eEe+++e++Ll+
  EEA18597.1 224 gnlRGQRAIELLNLPFDNEEESWFEEYLLK 253
                 **977999********************87 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       430  (0.0239835); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.30s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 2018.99
//
Query:       EEA18598.1  [L=1464]
Description: nuclear condensin complex subunit Smc4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-63  214.5  47.0    8.7e-63  211.7  47.0    2.7  1  SMC_N          RecF/RecN/SMC N terminal domain
      4e-25   88.4   0.1    2.5e-24   85.8   0.0    2.4  2  SMC_hinge      SMC proteins Flexible Hinge Domain
    3.1e-11   43.6   4.5      5e-05   23.2   0.0    3.6  4  AAA_21         AAA domain, putative AbiEii toxin, Type IV TA 
    2.2e-07   30.9   6.3    2.2e-07   30.9   6.3    4.4  4  AAA_15         AAA ATPase domain
    7.3e-05   22.4   0.0     0.0019   17.9   0.0    2.5  2  AAA_29         P-loop containing region of AAA domain
     0.0003   21.0   5.5     0.0003   21.0   5.5    7.8  8  Tropomyosin_1  Tropomyosin like
    0.00069   18.4  30.6    0.00069   18.4  30.6    6.0  7  AAA_13         AAA domain


Domain annotation for each model (and alignments):
>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  211.7  47.0   3.4e-66   8.7e-63       2     219 ..     251    1440 ..     250    1441 .. 0.99

  Alignments for each domain:
  == domain 1  score: 211.7 bits;  conditional E-value: 3.4e-66
                  EEEEEEESETTEECEEEEEETTSSEEEEEESTTSSHHHHHHHHHHHCTT.TTTTTTCHCCCCCC--BTTCSSTTEEEEEEEEEETTEE.....SSSS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxx RF
       SMC_N    2 lkrleienFksyagktvilpfsksftaivGpNGSGKsnlldAilFvLGersakklrseklsdlihkskekasvkkaeveitfdnedkk.....lkie 93  
                  +++l+++nFksyagk++++pf+ sf+++vGpNGSGKsn++d++lFv+G+r++ k+r+ k+s+lih+s++ + ++++eve++f++  +       ++ 
  EEA18598.1  251 ITHLVLTNFKSYAGKQIVGPFHVSFSSVVGPNGSGKSNVIDSLLFVFGFRAS-KMRQGKISALIHNSARFPDLTFCEVEVHFQEIMDLpggahKVVP 346 
                  899**********************************************988.*****************************765544455458999 PP

                  SSCEEEEEEEETTSEEEEEETTEEE-HHHHHHHHHCTT-STT....................................................... CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....................................................... RF
       SMC_N   94 keevsisrrvkrkgeseykingkevtkkevsellesagiske....................................................... 135 
                  ++++++srr++++++s+y++n+ke +++ v+ +l++ gi+ +                                                       
  EEA18598.1  347 DSQLVVSRRAFKNNSSKYYMNKKETNFTTVTTFLKDRGIDLDhkrflilqgevesiaqmkpkagnehedglleylediigtskyktpieeaaaevet 443 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA18598.1  444 lndvcveknnrvqhvekektaledkkdkalayirdendltmkqsalyqvyiaecennnkvteeaimqmqellnmelekhegnesgikeiekkykrvt 540 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA18598.1  541 keyesmekttqamikemakydkeavkfeekrkfltgkqkkldktlqtsrlassecsslvekhasdiekksaeivqledemkteeeelasireslkgk 637 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA18598.1  638 tqglsdqiaakqkslepwnakindklssiavaqseldilhergnagakaleeaqvrvstieeslaekeseleekhqektqleaeveslkkdlnklsq 734 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA18598.1  735 kepelrsyvsnarqkaeearaslastqnkgsvlsglmrlkesgrvegfhgrlgnlgtieekydvaistacpqlenmvvdtvesgqqcidylrknnlg 831 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA18598.1  832 ranfilldrlpkrnmstiftpesvprlfdlvkpkdakfapafysvlqntlvakdleqanriaygakrwrvvtldgqlidlsgtmsgggtrvakggms 928 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA18598.1  929 skqvaetskeqvsklefdrdewekklqlfqdkqrqletslrqkseeipkldtkiqkigieiesgkrslvdaqrrmkelsvehkpsktdenrakalnq 1025
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA18598.1 1026 qikalqrevenlrqdmagieeeiqslqakimevggvrlrsqkakvdslkaqinllseeisnaevakskneklikkhekarleaekdseqlnaeierl 1122
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA18598.1 1123 eedvknqandasgsrqqaedaqealetkrgeikalkqeldektaelnetraqeiemrnkleenqkvltenqkrsryweeklsklslqnvsdlgdaqe 1219
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA18598.1 1220 taelqaftadeladmnkeslkaviaaleektqnasvdlsvideyrrrvaehetrsadlnesltardaakarldglrsarltgfmegfstislrlkem 1316
                  ************************************************************************************************* PP

                  ........................................CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEE CS
                  ........................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  136 ........................................lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQf 192 
                                                          +LSgGektL++laL+fA++++kp+ply++DeidaaLD++nv++va+++ke++knaQf
  EEA18598.1 1317 yqmitmggnaelelvdsldpfsegilfsvmppkkswknisNLSGGEKTLSSLALVFALHHYKPTPLYVMDEIDAALDFRNVSIVASYIKERTKNAQF 1413
                  ************************************************************************************************* PP

                  EEE-SSHHHCCC-SCEEEEEEEETTEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  193 ivislreemlekadklvgvtkvengvs 219 
                  ivislr++m+e a++lvgv+kv++ ++
  EEA18598.1 1414 IVISLRNNMFELASRLVGVYKVNHMTK 1440
                  *********************887765 PP

>> SMC_hinge  SMC proteins Flexible Hinge Domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.8   0.0   9.9e-28   2.5e-24       2     117 .]     780     893 ..     779     893 .. 0.97
   2 ?   -1.7   0.1       1.4   3.5e+03      12      36 ..    1232    1256 ..    1227    1277 .. 0.67

  Alignments for each domain:
  == domain 1  score: 85.8 bits;  conditional E-value: 9.9e-28
   SMC_hinge   2 kgvlGrladlievdegyekAveaalgnrlqalvvedeetakkiieflkkknagratflpldrikqknkadgandknsgavplidlvevdde.lrkalry 99 
                 +g++Grl++l +++e+y++A+++a+ ++l++ vv++ e+ +++i++l+k+n+gra+f+ ldr+ ++n +   +++   + +l+dlv+ +d+ +++a++ 
  EEA18598.1 780 EGFHGRLGNLGTIEEKYDVAISTAC-PQLENMVVDTVESGQQCIDYLRKNNLGRANFILLDRLPKRNMSTIFTPE--SVPRLFDLVKPKDAkFAPAFYS 875
                 799********************99.56*******************************************9998..6********************* PP

   SMC_hinge 100 llgdtlvvdsldeAeela 117
                 +l++tlv+++l++A+++a
  EEA18598.1 876 VLQNTLVAKDLEQANRIA 893
                 ***************986 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 1.4
   SMC_hinge   12 ievdegyekAveaalgnrlqalvve 36  
                    + ++  kAv aal+++ q+  v+
  EEA18598.1 1232 ADMNKESLKAVIAALEEKTQNASVD 1256
                  4455566667777777776665554 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.2   0.0     2e-08     5e-05       3      28 ..     277     303 ..     275     340 .. 0.77
   2 ?   -3.2   0.0       2.2   5.7e+03     112     188 ..     360     437 ..     351     461 .. 0.80
   3 ?   -2.4   0.1       1.2   3.2e+03      95     168 ..     642     715 ..     618     761 .. 0.58
   4 !   20.3   0.1   1.6e-07    0.0004     233     296 ..    1354    1417 ..    1179    1417 .. 0.87

  Alignments for each domain:
  == domain 1  score: 23.2 bits;  conditional E-value: 2e-08
      AAA_21   3 vliGpNgsGKSnLLdaldllarl.drd 28 
                  ++GpNgsGKSn++d l +++++ ++ 
  EEA18598.1 277 SVVGPNGSGKSNVIDSLLFVFGFrASK 303
                 58*******************975222 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.2
      AAA_21 112 npeargirggvsvfslkelsvsepndlqfgkaltditsrawsllllldglrke.rigllnifadyfgfakekrllqrl 188
                 n+ +++  + +++f   +  +++  ++   k+++ +  + +s+++++ + ++e + gll++  d +g +k k+ +++ 
  EEA18598.1 360 NSSKYYMNKKETNFTTVTTFLKDRGIDLDHKRFLILQGEVESIAQMKPKAGNEhEDGLLEYLEDIIGTSKYKTPIEEA 437
                 555666667777777778888888888888999999999999999999999999999999999999988888877765 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 1.2
      AAA_21  95 esgllldkrsleeedvfnpeargirggvsvfslkelsvsepndlqfgkaltditsrawsllllldglrke.rigl 168
                 ++ +  + +sle ++++++++  + ++++++ ++ +++ ++ ++  ++a ++++   +sl++   +l ++ +   
  EEA18598.1 642 SDQIAAKQKSLEPWNAKINDKLSSIAVAQSELDILHERGNAGAKALEEAQVRVSTIEESLAEKESELEEKhQ-EK 715
                 555555566666666666666666666666666666666666666666666666666666555555555532.22 PP

  == domain 4  score: 20.3 bits;  conditional E-value: 1.6e-07
      AAA_21  233 parelSdGtkrll..alltallralkkgsllliDEpEngLHPkllrrllellkelsrngaQviltT 296 
                  ++++lS G k l   al+ al+   +  +l++ DE+++ L+ + ++ ++  +ke ++ +aQ+i+ +
  EEA18598.1 1354 NISNLSGGEKTLSslALVFALHHYKPT-PLYVMDEIDAALDFRNVSIVASYIKERTK-NAQFIVIS 1417
                  68899*******655888888888888.************************99999.9****976 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.3       1.3   3.3e+03     202     258 ..     177     227 ..      91     241 .. 0.66
   2 !   30.9   6.3   8.5e-11   2.2e-07       1     265 [.     249     551 ..     249     570 .. 0.61
   3 ?   -2.6  19.3       1.3   3.3e+03     102     260 ..     568     733 ..     553     767 .. 0.73
   4 ?  -15.4  35.1         7   1.8e+04     100     286 ..     949    1164 ..     927    1238 .. 0.46

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 1.3
      AAA_15 202 akRnvsdedsekkssllgklkekileealqekleeelteklkeiqeklkeidkklae 258
                 + R++s+ +s+ ++s+ +k +  ++ +       ee++++++ i++  ++++k ++ 
  EEA18598.1 177 SHREFSSPLSDITQSAVNKSPAPTKTD------AEEQKSQISIINSQSTNLEKPMDI 227
                 567777777777777777777777776......455666666666666666665554 PP

  == domain 2  score: 30.9 bits;  conditional E-value: 8.5e-11
      AAA_15   1 MkIkkikikNFRslkdvei..dlseeltvliGkNnsGKSsilealdlFlnnkekkn........................................... 54 
                 M I+ + + NF+s+   +i  ++  +++ ++G+N+sGKS++++ l + +    +k                                            
  EEA18598.1 249 MVITHLVLTNFKSYAGKQIvgPFHVSFSSVVGPNGSGKSNVIDSLLFVFGFRASKMrqgkisalihnsarfpdltfcevevhfqeimdlpggahkvvpd 347
                 999999********997773456666**********************998865558999999999999999999999999999999999999999999 PP

      AAA_15  55 ...............kkvikiekedleifeniseskdikIdvef......aekekakeyektlkskekkkadlllkkkesdlkktikdkklklk.k.ne 130
                                k   + +k++++ +  + + kd  Id+        +  ++  e +  +k+k+ ++ +  l +  +d+  t+k k+   + + + 
  EEA18598.1 348 sqlvvsrrafknnssK--YYMNKKETNFTTVTTFLKDRGIDLDHkrflilQ--GEV-ESIAQMKPKAGNEHEDGLLEYLEDIIGTSKYKTPIEEaAaEV 441
                 9999988888888443..444444444444455555544444443344330..333.334455555555555555555555555444444333303033 PP

      AAA_15 131 lsdekisvekkkskkelpkekeeklekekeelkidkedlkklikkleeslkkeeelknvlksaiiklllisakRnvsdedsekkssllgklkekileea 229
                  + + ++vek++  ++ +kek+  ++k+++ l +  ++++ + k                  ++ ++++  a+ +++++ +e+    + +l++  le+ 
  EEA18598.1 442 ETLNDVCVEKNNRVQHVEKEKTALEDKKDKALAYIRDENDLTMK------------------QSALYQVYIAECENNNKVTEEAIMQMQELLNMELEK- 521
                 33455666777777777777777777777777777777776666..................123344444555555555555455555555555554. PP

      AAA_15 230 lqekleeelteklkeiqeklkeidkklaeelkkilk 265
                      +e +++ +kei++k+k   k++++ +k + +
  EEA18598.1 522 -----HEGNESGIKEIEKKYKRVTKEYESMEK-TTQ 551
                 .....555555555555555555555533333.222 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 1.3
      AAA_15 102 kkadlllkkkesdlkktikdkklklkknelsdekisvekkkskkelpkekeeklekekeelkid...kedlkklikkleeslkkeeelknvlksaiikl 197
                 +++ + l+ k+++l+kt+++  l+ ++    +ek+  + +k++ e+  +++e++++e+e  +i    k +++ l++++  + k+ e ++ ++++++  +
  EEA18598.1 568 EEKRKFLTGKQKKLDKTLQTSRLASSECSSLVEKHASDIEKKSAEIVQLEDEMKTEEEELASIReslKGKTQGLSDQIAAKQKSLEPWNAKINDKLSSI 666
                 3334578999********************************999999999999999999999888888899999988888888889************ PP

      AAA_15 198 llisakRnvsdedsekkssllgklkeki..leealqekl..eeelteklkeiqeklkeidkklaeel 260
                  + +++ ++ +e+ +   ++l++++ +   +ee+l+ek    ee+ ++  +++ +++ ++k+l++  
  EEA18598.1 667 AVAQSELDILHERGNAGAKALEEAQVRVstIEESLAEKEseLEEKHQEKTQLEAEVESLKKDLNKLS 733
                 ****************999999988765004444444445623333333333333333333332222 PP

  == domain 4  score: -15.4 bits;  conditional E-value: 7
      AAA_15  100 ekkkadlllkkkesdlkktikdkklklkknelsdekisvekkkskkelpkekeeklekekeelkid.kedlkklikkleeslkkee........... 184 
                  e +k+  l+++k+++l + +++k  +++k +++ +ki +e +  k++l + ++ ++e++ e+   + +e+  k +++ ++ l+ e            
  EEA18598.1  949 EWEKKLQLFQDKQRQLETSLRQKSEEIPKLDTKIQKIGIEIESGKRSLVDAQRRMKELSVEHKPSKtDENRAKALNQQIKALQREVenlrqdmagie 1045
                  3344445677777777777777777777777777777777776644444444444433333332222333333333333333333344444555444 PP

      AAA_15  185 .....................................elknvlksaiiklllisakRnvsdedsekkssllgklkekileealqekl........ee 236 
                                                       e++n   ++++                                               ++
  EEA18598.1 1046 eeiqslqakimevggvrlrsqkakvdslkaqinllseEISNAEVAKSKNE------------------------------------KlikkhekaRL 1106
                  43333334444444444443333333333333333332222222222222....................................13444444444 PP

      AAA_15  237 elteklkeiqeklkeidkklaeelk.......................kilkkkidkikkfnykgkkneeiei 286 
                  e ++++++++ +++ ++++++++++                       k lk+ +d+                
  EEA18598.1 1107 EAEKDSEQLNAEIERLEEDVKNQANdasgsrqqaedaqealetkrgeiKALKQELDE---------------K 1164
                  444444444444444444444444444444444432222222222222222222222...............1 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.0   7.4e-07    0.0019       3      46 ..     253     297 ..     251     303 .. 0.78
   2 ?    1.4   0.0      0.11   2.8e+02      31      42 ..     989    1000 ..     985    1003 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 7.4e-07
      AAA_29   3 rlqlvNWgtfdghti..eidlkgatlltGpsGsGKSTllDAiqalL 46 
                 +l l N  ++ g++i  +++++ +  ++Gp+GsGKS ++D++ +++
  EEA18598.1 253 HLVLTNFKSYAGKQIvgPFHVS-FSSVVGPNGSGKSNVIDSLLFVF 297
                 6778888999995552244444.799***************99885 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.11
      AAA_29   31 sGsGKSTllDAi 42  
                  ++sGK +l+DA+
  EEA18598.1  989 IESGKRSLVDAQ 1000
                  68*********7 PP

>> Tropomyosin_1  Tropomyosin like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   0.4         6   1.5e+04      26      37 ..     107     118 ..      97     147 .. 0.67
   2 ?   -6.6  24.2         7   1.8e+04      17     135 ..     435     568 ..     427     572 .. 0.55
   3 ?    1.8  17.4     0.095   2.4e+02      16     134 ..     543     666 ..     540     673 .. 0.70
   4 !    5.7  12.9    0.0061        16      10      73 ..     688     751 ..     677     763 .. 0.65
   5 !   21.0   5.5   1.2e-07    0.0003       3      67 ..     941    1005 ..     939    1018 .. 0.90
   6 !    7.0  15.9    0.0024       6.2      19     109 ..    1016    1103 ..    1002    1111 .. 0.78
   7 ?    0.5  33.3      0.24   6.1e+02      18     136 ..    1093    1208 ..    1086    1212 .. 0.72
   8 ?   -0.9   0.8      0.67   1.7e+03      67      96 ..    1228    1257 ..    1208    1272 .. 0.69

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 6
  Tropomyosin_1  26 leqenlekeqei 37 
                     eqen+e ++e 
     EEA18598.1 107 VEQENEEDDEEA 118
                    455555555444 PP

  == domain 2  score: -6.6 bits;  conditional E-value: 7
  Tropomyosin_1  17 eeleekvKeleqenlekeqeiksLtkknqqleeevekleeklkeakek............aeesekkktnnealtrkiqlLEeelee...sdkkLk 97 
                    ee+ ++v +l++  +ek++ ++  +k   +le++ +k+ + +++ ++             ae ++++k + ea+ +  +lL  ele+   +++ +k
     EEA18598.1 435 EEAAAEVETLNDVCVEKNNRVQHVEKEKTALEDKKDKALAYIRDENDLtmkqsalyqvyiAECENNNKVTEEAIMQMQELLNMELEKhegNESGIK 530
                    555555555555555555555555555555555555555555444433100000111111455556666666777777777777766222455678 PP

  Tropomyosin_1  98 ettekLretdvkaeelERkvkaLeqerdewekkyeele 135
                    e  +k + + ++ e +E+ ++a+ +e ++++k   ++e
     EEA18598.1 531 EIEKKYKRVTKEYESMEKTTQAMIKEMAKYDKEAVKFE 568
                    88888888888888888888887777777766555555 PP

  == domain 3  score: 1.8 bits;  conditional E-value: 0.095
  Tropomyosin_1  16 aeeleekvKeleqenlekeqeiksLtkknqqleeevekleeklkeakekaee....sekkktnnealtrkiqlLEeeleesdkkLkettekLr.et 106
                    +e +e+  +++ +e  + ++e  + ++k + l  +  kl+++l++++ +++e     ek++++ e+ +  i +LE+e+   +++L++  e L+ +t
     EEA18598.1 543 YESMEKTTQAMIKEMAKYDKEAVKFEEKRKFLTGKQKKLDKTLQTSRLASSEcsslVEKHASDIEKKSAEIVQLEDEMKTEEEELASIRESLKgKT 638
                    4445555555555555555555555555555555555555555555444333111157889999999999**********************9568 PP

  Tropomyosin_1 107 dvkaeelERkvkaLeqerdewekkyeel 134
                    +  ++++  k k+Le  +++ ++k+  +
     EEA18598.1 639 QGLSDQIAAKQKSLEPWNAKINDKLSSI 666
                    8899**********99998888887665 PP

  == domain 4  score: 5.7 bits;  conditional E-value: 0.0061
  Tropomyosin_1  10 eeaqekaeeleekvKeleqenlekeqeiksLtkknqqleeevekleeklkeakekaeesekkkt 73 
                    eeaq +++ +ee++ e+e+e +ek qe ++L+  ++ l ++++kl++k  e ++ ++++ +k+ 
     EEA18598.1 688 EEAQVRVSTIEESLAEKESELEEKHQEKTQLEAEVESLKKDLNKLSQKEPELRSYVSNARQKAE 751
                    5666777777777777777777777777777777777777777666665555555555554444 PP

  == domain 5  score: 21.0 bits;  conditional E-value: 1.2e-07
  Tropomyosin_1    3 nsLkleaeeaqekaeeleekvKeleqenlekeqeiksLtkknqqleeevekleeklkeakekaee 67  
                     ++L  + +e+ +k +  ++k ++le +  +k +ei +L +k+q++  e+e  + +l +a++ ++e
     EEA18598.1  941 SKLEFDRDEWEKKLQLFQDKQRQLETSLRQKSEEIPKLDTKIQKIGIEIESGKRSLVDAQRRMKE 1005
                     68999****************************************************99987766 PP

  == domain 6  score: 7.0 bits;  conditional E-value: 0.0024
  Tropomyosin_1   19 leekvKeleqenlekeqeiksLtkknqqleeevekleeklkeakekaeesekkktnnealtrkiqlLEeeleesdkkLkettekLretdvk 109 
                      e+++K+l+q+ ++   e+++L + +  +eee+  l++k++e+        ++k++ ++l+ +i+lL ee+ +++   k+ +ekL +   k
     EEA18598.1 1016 DENRAKALNQQIKALQREVENLRQDMAGIEEEIQSLQAKIMEVGGVRLR--SQKAKVDSLKAQINLLSEEISNAEVA-KSKNEKLIKKHEK 1103
                     4678899999999999999999999999999999999999998776554..5667789*************999864.7888888655544 PP

  == domain 7  score: 0.5 bits;  conditional E-value: 0.24
  Tropomyosin_1   18 eleekvKeleqenlekeqeiksLtkknqqleeevekleeklkeakekaeesekkktnnealtrkiqlLEeeleesdkkLkettekLretdvkae 111 
                     + e+ +K+ e+ +le e++ ++L+  ++ lee+v +  ++ + ++++ae+++++    e+    i+ L +el+e  ++L+et  +  e+  k e
     EEA18598.1 1093 KNEKLIKKHEKARLEAEKDSEQLNAEIERLEEDVKNQANDASGSRQQAEDAQEA---LETKRGEIKALKQELDEKTAELNETRAQEIEMRNKLE 1183
                     334456666666666666666666666666666666555555555555554433...334445699*******************999999999 PP

  Tropomyosin_1  112 elERkvkaLeqerdewekkyeelee 136 
                     e  +  ++ ++++  we+k+ +l+ 
     EEA18598.1 1184 ENQKVLTENQKRSRYWEEKLSKLSL 1208
                     99999999999********998875 PP

  == domain 8  score: -0.9 bits;  conditional E-value: 0.67
  Tropomyosin_1   67 esekkktnnealtrkiqlLEeeleesdkkL 96  
                     + e +++n+e+l+  i  LEe   +++ +L
     EEA18598.1 1228 ADELADMNKESLKAVIAALEEKTQNASVDL 1257
                     344456777788888888888877777665 PP

>> AAA_13  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -5.4   3.4       4.1   1.1e+04      96     198 ..     118     219 ..     104     234 .. 0.41
   2 ?    0.1  18.5      0.09   2.3e+02     296     451 ..     411     569 ..     395     575 .. 0.68
   3 !    3.9  22.8    0.0064        16     282     462 ..     575     752 ..     571     766 .. 0.56
   4 !    4.3   1.4    0.0049        13     420     472 ..     935     987 ..     927     991 .. 0.85
   5 !   18.4  30.6   2.7e-07   0.00069     272     458 ..     963    1166 ..     955    1174 .. 0.85
   6 ?    1.0   8.3     0.048   1.2e+02     279     378 ..    1180    1281 ..    1165    1292 .. 0.78
   7 ?   -2.3   0.0       0.5   1.3e+03     498     565 ..    1356    1415 ..    1319    1421 .. 0.64

  Alignments for each domain:
  == domain 1  score: -5.4 bits;  conditional E-value: 4.1
      AAA_13  96 ekieklkkeikkleekleaaeaqlqkaekekkklekeledeawkkivkkknsalsealkglkyeekfkerllkelkkk..nrkaaellsdeelkak.le 191
                 + i  +++  ++ +ek++aa++ +++a+++k    ++ + e++           s +++  +++ + ++  l+++ +   n+++a+ ++d+e+++  ++
  EEA18598.1 118 ATIIAAQEGPESPSEKVHAAQKRKRAASSRKSRDSATPAAELSS----LPTPSPSASPEASSRSHREFSSPLSDITQSavNKSPAPTKTDAEEQKSqIS 212
                 33333333333334444444444444444433333333333333....333444555555555444444444444433123333333333333322144 PP

      AAA_13 192 tvesenl 198
                 +++s++ 
  EEA18598.1 213 IINSQST 219
                 4444433 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.09
      AAA_13 296 eskkselleklkavsdeasensafeedkeelka......eaealeeqLkglqraleaKrkepfksvelesvkakiesikklvaeineliakhNekvan. 387
                 +++++ lle l++++ +++ +   ee+ +e+++      e+++  +  ++ + ale+K+++  +   + + ++ + + + l +   +  +++N+ +++ 
  EEA18598.1 411 NEHEDGLLEYLEDIIGTSKYKTPIEEAAAEVETlndvcvEKNNRVQHVEKEKTALEDKKDKALA--YIRDENDLTMKQSALYQVYIAECENNNKVTEEa 507
                 5566677777777777666555555554444442223334455555566777888888888777..455555666666777777788888999988762 PP

      AAA_13 388 leeekeeakkklelhlveeleseldeykkkykklekaieklekelkeeeaelkkleeeikeLek 451
                 + + +e ++ +le+h+ +  es ++e +kkyk+++k+ e++ek  ++  +e++k+++e+   e+
  EEA18598.1 508 IMQMQELLNMELEKHEGN--ESGIKEIEKKYKRVTKEYESMEKTTQAMIKEMAKYDKEAVKFEE 569
                 455566677889998888..67888999999999999999999999999999999999766655 PP

  == domain 3  score: 3.9 bits;  conditional E-value: 0.0064
      AAA_13 282 eekqerLekliekveskkselleklkavsdeasensafeedkeelkaeaealeeqLkglqraleaKrkepfksvelesvkaki.........esikklv 371
                 + kq++L+k++++   ++se++  +++ + +    ++   ++ +l++e+++ ee+L ++++ l+ K + ++ ++  ++ + +          +si  ++
  EEA18598.1 575 TGKQKKLDKTLQTSRLASSECSSLVEKHASD---IEKKSAEIVQLEDEMKTEEEELASIRESLKGKTQGLSDQIAAKQKSLEPwnakindklSSIAVAQ 670
                 5689999999999999988886666554443...22345567777777777777777777777777777777444333222221111111113444555 PP

      AAA_13 372 aeineliakhNekvanleeekeeakkklelhlveeleseldeykkkykklekaieklekelkeeeaelkkleeeikeLekqlrdekpaaee 462
                 +e+  l ++ N+  + lee++ ++ + +e   ++e esel+e ++++ +le+++e+l+k+l++ +++  +l+  +++ +++        ee
  EEA18598.1 671 SELDILHERGNAGAKALEEAQVRVST-IEE-SLAEKESELEEKHQEKTQLEAEVESLKKDLNKLSQKEPELRSYVSNARQKA-------EE 752
                 55555555555555555544433322.333.234455666666666666666666666666666666666666665555544.......43 PP

  == domain 4  score: 4.3 bits;  conditional E-value: 0.0049
      AAA_13 420 klekaieklekelkeeeaelkkleeeikeLekqlrdekpaaeeinkeLkafGl 472
                   +++++kle + +e e++l+  +++ ++Le++lr++ + + ++ ++++++G+
  EEA18598.1 935 TSKEQVSKLEFDRDEWEKKLQLFQDKQRQLETSLRQKSEEIPKLDTKIQKIGI 987
                 45678999999999999999999999999999999999999999999999996 PP

  == domain 5  score: 18.4 bits;  conditional E-value: 2.7e-07
      AAA_13  272 aLeahFddefeekqerLekliekveskkselleklkavsdeasensafeedkeelkaeaealeeqLkglqraleaKrkepfk.svelesvkakie.. 365 
                  +Le    +++ee + +L+ +i+k+  ++++ + +l ++  + +e s  ++  ++ +++a+al++q+k+lqr++e+ r++++  + e++s++aki   
  EEA18598.1  963 QLETSLRQKSEE-IPKLDTKIQKIGIEIESGKRSLVDAQRRMKELSVEHKPSKTDENRAKALNQQIKALQREVENLRQDMAGiEEEIQSLQAKIMev 1058
                  566666665555.8899999999999999888889888888888888888888889999**********************97888********446 PP

      AAA_13  366 ......sikklvaeineliakhNekvanleeekeeakkklelhlv.........eeleseldeykkkykklekaieklekelkeeeaelkkleeeik 447 
                        s k +v++++++i+   e ++n e +k++ +k +++h+          e+l++e++++++++k+ +++++   +++++++++l+++++eik
  EEA18598.1 1059 ggvrlrSQKAKVDSLKAQINLLSEEISNAEVAKSKNEKLIKKHEKarleaekdsEQLNAEIERLEEDVKNQANDASGSRQQAEDAQEALETKRGEIK 1155
                  66667699************************************97888888888888999999999999999999999999999999999999999 PP

      AAA_13  448 eLekqlrdekp 458 
                  +L+++l +++ 
  EEA18598.1 1156 ALKQELDEKTA 1166
                  99998877665 PP

  == domain 6  score: 1.0 bits;  conditional E-value: 0.048
      AAA_13  279 defeekqerLekliekveskksellek.lkavsdeasensafeedkeelkaeaealeeqLkglqraleaKrkepfksve.lesvkakiesikklvae 373 
                  ++ ee+q+ L + +++    +++l++  l++vsd  ++++ +e +  ++++ a+  +e+Lk++  ale+K ++ + +++ ++++  ++ + +   a+
  EEA18598.1 1180 NKLEENQKVLTENQKRSRYWEEKLSKLsLQNVSDLGDAQETAELQAFTADELADMNKESLKAVIAALEEKTQNASVDLSvIDEYRRRVAEHETRSAD 1276
                  456777777877777665555555444499****9999999999999999999*******************9999998558888888888888888 PP

      AAA_13  374 ineli 378 
                  +ne+ 
  EEA18598.1 1277 LNESL 1281
                  88765 PP

  == domain 7  score: -2.3 bits;  conditional E-value: 0.5
      AAA_13  498 etLSeGEkta..IaflYFlkslkeddseigkdkivviDDPvSSLDsnslfivfsliksrllkkkkakQlf 565 
                   +LS GEkt+   a+++ l+  k            v+D     LD   + iv+s+ik+r+   k+a+ + 
  EEA18598.1 1356 SNLSGGEKTLssLALVFALHHYKPT-------PLYVMDEIDAALDFRNVSIVASYIKERT---KNAQFIV 1415
                  5666666665334444444444411.......1122333335688888888888888888...5555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1464 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3131  (0.174633); expected 358.6 (0.02)
Passed bias filter:                      633  (0.0353059); expected 358.6 (0.02)
Passed Vit filter:                       248  (0.0138323); expected 17.9 (0.001)
Passed Fwd filter:                       136  (0.00758548); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 3.52u 0.39s 00:00:03.91 Elapsed: 00:00:00.78
# Mc/sec: 5675.91
//
Query:       EEA18599.1  [L=116]
Description: 40S ribosomal protein S10a [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.3e-26   91.9   0.5    2.7e-26   91.6   0.5    1.0  1  Ribosomal_S10  Ribosomal protein S10p/S20e


Domain annotation for each model (and alignments):
>> Ribosomal_S10  Ribosomal protein S10p/S20e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.6   0.5   1.5e-30   2.7e-26       1      98 []      20     113 ..      20     113 .. 0.96

  Alignments for each domain:
  == domain 1  score: 91.6 bits;  conditional E-value: 1.5e-30
                    EEEEEESSHHHHHHHHHHHHHHTTSSS-EE---EEEEEEEEEEEEE--SS--.S--EEEEEEEEEEEEEEEE.E-HHHHHHHS-...S---SS-EE CS
  Ribosomal_S10   1 rirlkSydsklLekavkkivraakelgikvkgpvplPtkrkrvtvlksphvd.kksreqfeirthkRlidisdatketidtllkllqlnlpegVsv 95 
                    ri+l+S++ ++Lek+++++++ ak+++++vkgpv+lPtk++++ ++k+p ++ +k+++ +e+r+hkRlid++ a+ et+++++     n+++gV+v
     EEA18599.1  20 RITLSSRKVASLEKVCQELIERAKSKSLTVKGPVRLPTKTLKISTRKTPNGEgSKTWDTYEMRIHKRLIDLH-APTETVKQIII----NIEAGVEV 110
                    89*********************************************************************5.99999999998....899***** PP

                    EEE CS
  Ribosomal_S10  96 evk 98 
                    ev+
     EEA18599.1 111 EVT 113
                    996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (116 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       518  (0.0288917); expected 358.6 (0.02)
Passed bias filter:                      395  (0.0220313); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.27s 00:00:00.65 Elapsed: 00:00:00.43
# Mc/sec: 817.02
//
Query:       EEA18600.1  [L=709]
Description: CUE domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.7e-09   34.8   0.0    2.3e-08   33.6   0.0    1.7  1  CUE            CUE domain
  ------ inclusion threshold ------
       0.01   15.4   0.2       0.15   11.7   0.0    2.5  2  Mso1_Sec1_bdg  Sec1-binding region of Mso1
        3.8    6.9   6.1        1.5    8.2   0.8    2.5  2  ORC5_C         Origin recognition complex (ORC) subunit 5 C-t


Domain annotation for each model (and alignments):
>> CUE  CUE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.6   0.0   3.9e-12   2.3e-08       4      41 ..     355     392 ..     353     393 .. 0.94

  Alignments for each domain:
  == domain 1  score: 33.6 bits;  conditional E-value: 3.9e-12
                 HHHHHHHHSTTS-HHHHHHHHHHCTTTHHHHHHHHHHC CS
         CUE   4 mletLkemFPdldeevIravLrasngnvEatinaLLeg 41 
                  + +++++FPdl+e++I++ L  ++ nvE+++  LLe 
  EEA18600.1 355 LITQIRDLFPDLGEGYIVRLLDYYTDNVETVVAHLLES 392
                 689*********************************96 PP

>> Mso1_Sec1_bdg  Sec1-binding region of Mso1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   2.5e-05      0.15       4      25 ..     213     234 ..     210     236 .. 0.88
   2 ?    0.5   0.3     0.078   4.7e+02       9      20 ..     495     506 ..     487     506 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 2.5e-05
  Mso1_Sec1_bdg   4 nlslssEkDGdteddTlvhraL 25 
                    +ls s+E+DG+   +Tlv ++ 
     EEA18600.1 213 SLSASNEADGNALRSTLVANVY 234
                    57888***************95 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.078
  Mso1_Sec1_bdg   9 sEkDGdteddTl 20 
                     ++D+d  ddT+
     EEA18600.1 495 FDSDDDERDDTY 506
                    599*******95 PP

>> ORC5_C  Origin recognition complex (ORC) subunit 5 C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   0.8   0.00026       1.5     140     171 ..      56      88 ..      55     108 .. 0.74
   2 ?    0.5   0.4      0.06   3.6e+02      52      96 ..     125     201 ..     114     352 .. 0.48

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.00026
      ORC5_C 140 AAYLASynpprlDlrlFsktsgks.kkrrkrrk 171
                 A++L Sy ++r D+rl +++ +   +k+ k  +
  EEA18600.1  56 ASFLTSYFAARDDARLHGTNASTTtTKKSKHLR 88 
                 9********************766444433322 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.06
      ORC5_C  52 rdipelrsiceklWprFva...P.ildgel..........kpe...........dfsrllaanralfrd........q 96 
                 ++ ++l+++++++W r+ +   P i++g+l          k +           d+ rl  +++al++         +
  EEA18600.1 125 HSSSALKQLLSEVWTRYENvisPsIETGKLevmemllkakK-TgqvtaasdlvlDIRRLSILASALPQVgcllmtgsD 201
                 45568888889999998774432455555522222222220.012222222333333333333333333444443330 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (709 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       665  (0.0370907); expected 358.6 (0.02)
Passed bias filter:                      406  (0.0226449); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.42
# Mc/sec: 5022.19
//
Query:       EEA18601.1  [L=756]
Description: methylated-DNA--protein-cysteine methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   2.8e-108  362.8   1.4     4e-108  362.3   1.4    1.2  1  Glyco_hydro_92  Glycosyl hydrolase family 92
    1.9e-24   85.6   0.0    3.5e-24   84.7   0.0    1.5  1  DNA_binding_1   6-O-methylguanine DNA methyltransferase, DNA 


Domain annotation for each model (and alignments):
>> Glyco_hydro_92  Glycosyl hydrolase family 92
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  362.3   1.4  4.4e-112    4e-108       2     461 ..     258     736 ..     257     737 .. 0.86

  Alignments for each domain:
  == domain 1  score: 362.3 bits;  conditional E-value: 4.4e-112
                     HHHHHHHHTTT--HHHHHHHHHHHHHHH.HTTEEE...ESS-HHHHHHHHHHHHHHTTSSEE--EE-TTE-TTTSSEEE.S..--EESEEHHHHT CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxx RF
  Glyco_hydro_92   2 ArknleaEipdldfekvraaareaWnek.Lskiev...eggtedqkttFYtalYhallapneysdvdgeYsglddkvhkeg..ksYttfslWDty 90 
                     A++ +++Eip++++++++++a ++Wn++ +ski+v   +++++++++++Y++lY ++l+ +++++ +  +   d+   + +  + Y  fs+  ty
      EEA18601.1 258 AKDYITTEIPTWSVNNTVTDAIHEWNTDvFSKIRVptdSSANTTNLRLLYSSLYFMHLMSSDRTGENPLWI-SDEPFWD-DfyTLYL-FSMEGTY 349
                     89999**********************99******55333699**********************777776.3333222.2224477.9****** PP

                     TTHHHH.HHHH-HHHHHHHHHHHHHHHHHHSS--SEESSS.B---S-S-THHHHHHHHHHTT--...-S-HHHHHHHHHHHHHB-S.-TT..... CS
                     xxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxx.xxxx.... RF
  Glyco_hydro_92  91 Raqhpl.ltlldperasdmvrslldiykeggwlpdwrlsnsetavmgGsnadvvladayvkgir...dfdvekayealvkdaeeep.eaad.... 176
                      a+ ++  ++l+p  +++m+r+l++iyk++g+lpd+r+ n+++ v+gGsn d+vladayvkg+r   +++  + y+a+vkdae++p ++ d    
      EEA18601.1 350 SAVRSVsTHVLQPPYYESMIRGLIEIYKHQGYLPDGRSGNWNGLVQGGSNGDNVLADAYVKGLRgsiNWT--EGYAAMVKDAEVTPyNTFDptdl 442
                     99988725799*****************88*********************************9866666..***********999666668888 PP

                     ...TBTTTHHHHHHHSS--T..T.T.TTHHHHHHHHHHHHHHHHHHHHHTT-HHH.HHHHTTGGGGGGGEETT......TTCE--B-TTS-B-SS CS
                     ...xxxxxxxxxxxxxxxxxxxx.x.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxx RF
  Glyco_hydro_92 177 ...kerrglesylklgYvpaked.e.sesvsrtlEyaydDfaiaqlAkalgkkedaekylkrsknwrnlfdpe......tgfmrprnadGtwaep 260
                        +++ ++ s+  ++ v++       ++v +     ++  +++q+A++++ ++d eky +rs+ w+ ++d++      tgf++pr a+G++++ 
      EEA18601.1 443 hpaQKKVEVLSMTGRNLVTY--LlTiIHAVFHVQLSIASMTSLSQVAAGIQ-PADKEKYVNRSAGWQLIWDHDvtslnfTGFLAPRFANGSYQDG 534
                     88633333555555555555..112244444444445566799*******7.8999*************************************** PP

                     --TT--.....STTSS.SS-HHHHTT--TT-HHHHHHHHTSHHHHHHHHHHHS----TTG...HHHHHHHTSS-TT-GGGTTGGGGGGGTT-HHH CS
                     xxxxxxx....xxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_92 261 fdpsedp....eegft.EgnawqysffvphDvagLielmGGkeafvkrLdslfeeeekks...edsaglsgqydhgNEpsfhtpylYnyagapwk 347
                     +dp +      ++ +  Eg +w+y+f++phDv++Li++mGG+ +f +rLd++fe+  +k+    + ag ++++++gNEp+f tpylY+y+++++k
      EEA18601.1 535 YDPLYCGgcewSS-IAyEGVPWEYTFSIPHDVETLIDFMGGPFTFDSRLDKMFEPGVAKQnlgVNGAGVTTLMNIGNEPDFGTPYLYHYVNKQAK 628
                     ***9988775444.446************************************988777778889999999************************ PP

                     HHHHHHHHHHHSB-SSTT-BSSTTTSSTTHHHHHHHHHTEE-SSTTS-EEEE---SSSEEEEE-GGG-EEEEE-TT-..BTTB-EEEEEEETTEE CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxx RF
  Glyco_hydro_92 348 tqervreildelynntpdGlpGndDaGqmsawyvfsalGlYpvapgspeyllgsPlfekvtirlengktltieaknn..saenvyvqsvtlnGkp 440
                     +           +++++ G+pGn+DaG+m++w++++ +GlYp+ +++p+yl+gsP+f++++++++ +ktl+i+a+++  ++ + yvqsv++nGk+
      EEA18601.1 629 SYS---------FKDAAYGIPGNSDAGAMNSWLLWQLVGLYPI-VTQPNYLIGSPWFPEINMTVNGNKTLRITATGSdyNEGSYYVQSVRVNGKE 713
                     975.........999999*************************.*****************************97664444567*********** PP

                     ---.EEEHHHH.HT-EEEEEEEE CS
                     xxx.xxxxxxx.xxxxxxxxxxx RF
  Glyco_hydro_92 441 lkk.wlthedi.akGgtLefelg 461
                     ++k wlth+di ++Gg+L+f+lg
      EEA18601.1 714 WDKnWLTHKDIfVDGGSLDFVLG 736
                     *666****776379******997 PP

>> DNA_binding_1  6-O-methylguanine DNA methyltransferase, DNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.7   0.0   3.9e-28   3.5e-24       1      81 []      54     139 ..      54     139 .. 0.94

  Alignments for each domain:
  == domain 1  score: 84.7 bits;  conditional E-value: 3.9e-28
                    HHHHHHHHHHTTS-TT-BEEHHHHHHHTT.TSCHHHHHHHHHTSSBTTTSGGGGEEBTTSBCCTTTT.......CHHHHHHHHHHTTS CS
  DNA_binding_1   1 afqqrVwellrqIpyGkvttYgeiAkllgkpkaaraVgqalaanplailvPcHRVvgadgklggyag.......glerkralLeaEgv 81 
                    +f++rV+++l ++p+G++ttY++i+k+l+  +++ra+g+a+++np+a+ vPcHRV+++d +lggy+g         ++k +lL  Egv
     EEA18601.1  54 PFRRRVYRILMSVPPGRWTTYSAISKHLN--SGPRAIGNAMKNNPFAPAVPCHRVLATDRSLGGYKGewvnggeYSTEKMKLLLDEGV 139
                    69***************************..**********************************77778877778889999999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (756 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       403  (0.0224776); expected 358.6 (0.02)
Passed bias filter:                      357  (0.0199119); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.77u 0.36s 00:00:01.12 Elapsed: 00:00:00.57
# Mc/sec: 3962.25
//
Query:       EEA18602.1  [L=342]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.3e-05   25.4   7.3     0.0018   18.6   0.4    2.8  3  zf-C2H2      Zinc finger, C2H2 type
     0.0018   18.9   3.7      0.015   16.1   0.5    2.6  2  zf-C2H2_4    C2H2-type zinc finger
  ------ inclusion threshold ------
      0.019   15.0   0.5      0.039   14.1   0.5    1.4  1  Zn-ribbon_8  Zinc ribbon domain
       0.08   13.0   4.2      0.092   12.8   0.5    2.3  2  zf-C2H2_6    C2H2-type zinc finger
       0.35   10.9   2.8        7.3    6.7   0.2    2.4  2  zf-BED       BED zinc finger


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.1       3.6   1.3e+04       7      17 ..     110     120 ..     110     120 .. 0.84
   2 !   18.6   0.4   5.1e-07    0.0018       1      23 []     264     287 ..     264     287 .. 0.95
   3 !   10.6   0.2   0.00017      0.62       9      23 .]     306     321 ..     293     321 .. 0.87

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 3.6
                 TEEESSHHHHH CS
     zf-C2H2   7 gksFkrksnLk 17 
                 gk F+ +s L+
  EEA18602.1 110 GKNFNFNSYLR 120
                 78999999985 PP

  == domain 2  score: 18.6 bits;  conditional E-value: 5.1e-07
                 EEETTTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirt.H 23 
                 ++C +CgksF+r  + krH ++ H
  EEA18602.1 264 FECQKCGKSFTRGADVKRHESSvH 287
                 89*****************99888 PP

  == domain 3  score: 10.6 bits;  conditional E-value: 0.00017
                 EESSHHHHHHHHHC.C CS
     zf-C2H2   9 sFkrksnLkrHirt.H 23 
                  F+r+++L+ H+rt H
  EEA18602.1 306 GFPRRDHLMEHLRTfH 321
                 6*************99 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.5   4.1e-06     0.015       1      24 []     264     287 ..     264     287 .. 0.94
   2 ?    3.4   0.2      0.05   1.8e+02       9      24 .]     306     321 ..     294     321 .. 0.86

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 4.1e-06
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlkthH 24 
                 f+C  CgksF++  +++rH  ++H
  EEA18602.1 264 FECQKCGKSFTRGADVKRHESSVH 287
                 89********88888******999 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.05
   zf-C2H2_4   9 sFsskkaLlrHlkthH 24 
                  F+++++L  Hl+t H
  EEA18602.1 306 GFPRRDHLMEHLRTFH 321
                 69999********998 PP

>> Zn-ribbon_8  Zinc ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.5   1.1e-05     0.039       5      30 ..     263     295 ..     261     298 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 1.1e-05
  Zn-ribbon_8   5 eYrCeeCghefe.....vlqsis.daplta.CP 30 
                   ++C++Cg+ f+     +++++s  +p++  CP
   EEA18602.1 263 SFECQKCGKSFTrgadvKRHESSvHSPQPMdCP 295
                  69*************9988889999999999*9 PP

>> zf-C2H2_6  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.5   2.6e-05     0.092       2      14 ..     264     276 ..     263     289 .. 0.83
   2 ?    1.1   0.2      0.12   4.2e+02      11      24 ..     307     321 ..     306     322 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 2.6e-05
   zf-C2H2_6   2 heCsvCsksFpsl 14 
                 +eC+ C+ksF  +
  EEA18602.1 264 FECQKCGKSFTRG 276
                 9*********976 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.12
   zf-C2H2_6  11 FpslqaLggHkks.H 24 
                 Fp  + L++H+++ H
  EEA18602.1 307 FPRRDHLMEHLRTfH 321
                 666678*****9955 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   0.2     0.002       7.3      17      29 ..     264     276 ..     259     288 .. 0.78
   2 ?    4.2   0.2     0.012        43      34      44 .]     312     322 ..     299     322 .. 0.86

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.002
                 -EETTTTEE---- CS
      zf-BED  17 avCryCgkilsrg 29 
                  +C  Cgk ++rg
  EEA18602.1 264 FECQKCGKSFTRG 276
                 58**********9 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.012
                 HHHHHHHHS-H CS
      zf-BED  34 nLkrHLrrkHp 44 
                 +L+ HLr++H+
  EEA18602.1 312 HLMEHLRTFHN 322
                 8*********5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       454  (0.0253221); expected 358.6 (0.02)
Passed bias filter:                      286  (0.0159518); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.66u 0.35s 00:00:01.01 Elapsed: 00:00:00.59
# Mc/sec: 1733.64
//
Query:       EEA18603.1  [L=391]
Description: hypothetical protein PMAA_008910 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      0.007   16.6   0.0      0.021   15.1   0.0    1.8  1  RRN9      RNA polymerase I specific transcription initiation 


Domain annotation for each model (and alignments):
>> RRN9  RNA polymerase I specific transcription initiation factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   1.2e-06     0.021       3      60 ..      64     124 ..      63     133 .. 0.69

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 1.2e-06
        RRN9   3 qlraeDLslHLYnafaLkrrlrkaeseea...eaneekeekeqeefvpskrWtAWPlpade 60 
                 ++r++ Ls  LY af++ +r ++   +++   + +e+++++ + ++   +  tAWPl++ +
  EEA18603.1  64 TTRRRNLSRLLYRAFLIEERRKSELLQRRedqSTDEDENRNLSVGLRSRDFITAWPLRPRD 124
                 5799*************66666443333222255555555566666666889*****9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (391 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       654  (0.0364772); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.66u 0.32s 00:00:00.98 Elapsed: 00:00:00.55
# Mc/sec: 2145.99
//
Query:       EEA18604.1  [L=520]
Description: nucleoside transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.5e-20   73.5  36.6      3e-20   72.4  36.6    1.5  1  Transp_cyt_pur  Permease for cytosine/purines, uracil, thiami
  ------ inclusion threshold ------
      0.014   14.2  15.5       0.42    9.4   0.7    3.2  3  LptF_LptG       Lipopolysaccharide export system permease Lpt
      0.075   12.9   0.2        0.3   11.0   0.1    2.1  2  UPF0139         Uncharacterised protein family (UPF0139)


Domain annotation for each model (and alignments):
>> Transp_cyt_pur  Permease for cytosine/purines, uracil, thiamine, allantoin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.4  36.6     5e-24     3e-20      13     433 ..      82     488 ..      69     494 .. 0.75

  Alignments for each domain:
  == domain 1  score: 72.4 bits;  conditional E-value: 5e-24
  Transp_cyt_pur  13 nlfsiWlganlnintwvigalglalgLnwwqsvlviivgnligaifvallglaGakyGlpfpilsRasfGirgsllplllrvviaivwfgvqawi 107
                      ++ +W +  +ni+ +++g lg ++gL+++qs+++ i+++++g++++a  + +Ga++Gl++  + R+sfG + + l ++l ++ +++w +v +++
      EEA18604.1  82 SMALLWASGTMNISCFATGFLGWEFGLSLKQSIVITIFASILGGAVTAYCASFGAATGLRQVSVGRFSFGWWPNKLIAILNGIQQLGWAAVACIT 176
                     46779****************************************************************************************** PP

  Transp_cyt_pur 108 Gsealllmlgkifgkwleiggailgtsltelvtffifwvvslvivllgvskirkffviaallvpvaafgfliwalvkaeg.Gpvldkavklgkse 201
                     G+ al+ + +                 +  +++++i  vv l+i+ +g + i  ++ +a +++ +++  +   + + a+   p +  +++l++s 
      EEA18604.1 177 GGLALTAVSDGH---------------VSLVLGIVILAVVALIISCFGLKYILIYERYAWIIFFIIFLIIFGETSKYADNtTPATATGANLSASV 256
                     ***998776554...............56777777777778888888888887777777776666654444444444444455555555555444 PP

  Transp_cyt_pur 202 .lflsavagvlagfatlilnapDFtryaktkkssvkiqlvavpllftlllligilvaaaakaayganawspldilakfdet.............. 281
                       +l+ v+g  a+++t++    D+    +   s +k++++++++  +++++ ++++ ++a+a  + ++w+ +     + +               
      EEA18604.1 257 lNLLAIVYGSSASWSTMAS---DYYAHYPVNVSRLKVFFMTTFGIGIPTSIGMVAGCVVASAFNNRPDWQDT-----YENQgigyliqdmlyphg 343
                     5588888888888888888...***********************************************987.....555554555666666544 PP

  Transp_cyt_pur 282 agvllililvalaqlgvnisanllsagldlaallPkkinikr....gsliaavialvivpwkllssssklftaflsllavflspvagviiadyfv 372
                     ++ +l  +lv+ +++ vni  +++s+g  ++ +   +++i r      ++aa+++l+    + l++  +    fl ll++  ++ + ++  + ++
      EEA18604.1 344 FAKFLLTLLVL-SGINVNI-ISIYSSGISFQQVSRPFAAIPRfiwtLLCFAAILGLALGGRQQLNTYLQ---DFLALLGYWCTSYTIILFEEHVF 433
                     44444333333.3344443.5688999998888754555544111144566666666666655554444...89999999999999999999999 PP

  Transp_cyt_pur 373 vrrgylklaalytrrrgsaYwyrkgvNwravaayivGiaaglvgvagsvgikvvkgaeklf 433
                      r+g+    +l   +  s+          a +a+++G++a  +g++    ++v + a++ +
      EEA18604.1 434 FRKGNFDNYDLEAWNDPSRLP----HGIGAAVAFLLGVVAWCMGMD--ETWFVGPLAKLIG 488
                     999988888877755566544....345678888888888888855..4677777777665 PP

>> LptF_LptG  Lipopolysaccharide export system permease LptF/LptG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.0   9.3e-05      0.56     256     347 ..      70     161 ..      16     167 .. 0.79
   2 ?    0.1   6.7     0.047   2.8e+02     277     349 ..     190     262 ..     187     267 .. 0.87
   3 ?    9.4   0.7     7e-05      0.42      81     131 ..     361     412 ..     344     437 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 9.3e-05
   LptF_LptG 256 kalrseglevrryraelhkrlalplaclvfaliaaplglvkrrggrglrlliaillfvlyyvllslgkalaengvl.ppilaawlpnilflll 347
                 ++ r  ++++++++a l+   ++ ++c++  +++  +gl++ +++ ++ ++ +il + +     s+g a + ++v+   +   w+pn l+++l
  EEA18604.1  70 EDKRPVHWREELSMALLWASGTMNISCFATGFLGWEFGLSL-KQSIVITIFASILGGAVTAYCASFGAATGLRQVSvGRFSFGWWPNKLIAIL 161
                 555666777888889999999********************.56666667778887777666666666777666662557799****999998 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.047
   LptF_LptG 277 alplaclvfaliaaplglvkrrggrglrlliaillfvlyyvllslgkalaengvlppilaawlpnilflllgl 349
                 +l l ++++a++a+ ++    ++ ++ +    i++f+++++++   +++a n++   + +a l+  ++ ll++
  EEA18604.1 190 SLVLGIVILAVVALIISCFGLKYILIYERYAWIIFFIIFLIIFGETSKYADNTTPATATGANLSASVLNLLAI 262
                 67788999999999999999999****99999********************999888888888777777776 PP

  == domain 3  score: 9.4 bits;  conditional E-value: 7e-05
   LptF_LptG  81 ltalrsaGislgrllrpilil.alllsvlsfllnnyvvPwankkaesllsei 131
                 ++ + s+Gis+ ++ rp+ ++  ++ ++l+f+  + ++  + ++++++l++ 
  EEA18604.1 361 IISIYSSGISFQQVSRPFAAIpRFIWTLLCFAAILGLALGGRQQLNTYLQDF 412
                 899***************8762677788888888888888888888888775 PP

>> UPF0139  Uncharacterised protein family (UPF0139)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.1   5.1e-05       0.3      43      90 ..     160     208 ..     156     213 .. 0.87
   2 ?   -2.9   0.0         1   6.3e+03      21      38 ..     248     264 ..     221     267 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 5.1e-05
     UPF0139  43 lmlklkwcaWvalvcslisfanskssd.dlkqilssfmlsvsalvmsYl 90 
                 ++  ++ + W+a+ c++  +a + +sd  +  +l  ++l+v+al+ s +
  EEA18604.1 160 ILNGIQQLGWAAVACITGGLALTAVSDgHVSLVLGIVILAVVALIISCF 208
                 555667789******************88899999*********99876 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1
     UPF0139  21 sqkedltpdymnllgmif 38 
                 + + +l   ++nll++++
  EEA18604.1 248 T-GANLSASVLNLLAIVY 264
                 2.3566666777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (520 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       997  (0.0556082); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.80u 0.42s 00:00:01.22 Elapsed: 00:00:00.60
# Mc/sec: 2615.96
//
Query:       EEA18605.1  [L=520]
Description: serine peptidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.8e-40  137.4   4.5    6.1e-30  104.4   0.1    2.1  2  Peptidase_S28  Serine carboxypeptidase S28


Domain annotation for each model (and alignments):
>> Peptidase_S28  Serine carboxypeptidase S28
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.4   0.1   3.4e-34   6.1e-30       2     180 ..      48     231 ..      47     300 .. 0.81
   2 !   33.8   1.7   8.9e-13   1.6e-08     289     417 ..     348     488 ..     329     504 .. 0.71

  Alignments for each domain:
  == domain 1  score: 104.4 bits;  conditional E-value: 3.4e-34
  Peptidase_S28   2 klDhFdasnkrtfqqryfvndqfykng.gpiflyiGgegslsasw..vsng.eilklAkefgAlvlslEHRfYGqSiPvkdlstenlrylsseqaL 93 
                     lDh d+ +  tf+qryf   +++k   +p+ l+  ge+ ++ ++    n      +A+efg++ l lEHR++G+S Pv  l+ + ++ l+ + aL
     EEA18605.1  48 LLDH-DKPALGTFKQRYFWSTEYWKGPgSPVILFQPGEQTAEGFQgyLFNKtITGVYAQEFGGAGLILEHRYWGESSPVDTLTPKTMQQLTFKNAL 142
                    5666.666778********999999866*******9999888654224455255579*************************************** PP

  Peptidase_S28  94 aDlasfikalkqkfkls.....ssskwitfGgSYsgsLaawarkkyPelvvgavaSSaPllakvdfkeylevvetslakvagecakaveqgf 180
                    aD+++f k ++  f +s     ++++wi+ GgSYsg+ a w+ +  P +  +  aSSaP++a  d+++y+  ++++l ++   c     + +
     EEA18605.1 143 ADAVYFAKNVELPFDNStksspQNAPWILAGGSYSGAQAGWTAATLPGTFWAYHASSAPVEAIWDYWQYFVPIQERLPHN---CSTDLVKVI 231
                    *********98555443112226789********************************************9999988654...444444444 PP

  == domain 2  score: 33.8 bits;  conditional E-value: 8.9e-13
  Peptidase_S28 289 yqlanaekkdsslesladdrqWlyqtCtE.fgfyqttds..eaqlfgskvpvelyidlCedvFgasynskkvsqavkat..nskYGgadnpkatnv 379
                    y+ +n  ++d+++   a+drqW++ +C+E fg +q +       + ++ v++++  ++C   F  +   ++ s++ k +   +++    +  +++v
     EEA18605.1 348 YNSSNPLYSDKTI-GNAADRQWMWFCCNEpFGSWQDAAPkgVPSIVSHLVTADYLFRTCGTFFQPDDGYTYASANGKRSdsLNAWTKGWTGTTERV 442
                    3444555555554.35789**********99*999887644567889999*************998777666665554400455776699999*** PP

  Peptidase_S28 380 vfvnGalDPWhalglkks.......tdssvvp.llikgaahcaDmy 417
                    ++ +G+ DPW+   ++++       t+ +  p +++++a+hc+D+ 
     EEA18605.1 443 IWAQGQYDPWREETISSDfrpggpaTSTEPNPiFVMPEASHCYDLL 488
                    **********9877555422222112222223257899*****986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (520 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       412  (0.0229795); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.73u 0.35s 00:00:01.08 Elapsed: 00:00:00.59
# Mc/sec: 2653.40
//
Query:       EEA18606.1  [L=229]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
     0.0034   16.7   0.1       0.12   11.6   0.0    2.1  2  ATP_bind_2  P-loop ATPase protein family
     0.0085   16.0   0.1      0.015   15.2   0.1    1.4  1  DUF1948     Domain of unknown function (DUF1948)
  ------ inclusion threshold ------
      0.045   14.1   0.1      0.069   13.5   0.1    1.4  1  DUF5097     Domain of unknown function (DUF5097)
      0.052   14.2   0.1        0.1   13.3   0.1    1.5  1  DnaI_N      Primosomal protein DnaI N-terminus
       0.11   12.7   0.0       0.18   12.0   0.0    1.3  1  GldM_C      GldM C-terminal domain


Domain annotation for each model (and alignments):
>> ATP_bind_2  P-loop ATPase protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0     0.015        54     182     226 ..      43      86 ..      39      94 .. 0.80
   2 !   11.6   0.0   3.5e-05      0.12     243     265 ..     137     159 ..     121     166 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.015
                 EEE-TTS--GGGSTTTT.TS-TTSHHHHHHHHHSHHHHHHHHHHHH CS
  ATP_bind_2 182 vfdvrflPnPhwveelr.PltGkdkevaeyvlkrtevaefieklrs 226
                  +++r lPnP    +lr   tG  + +++  l+  +v+ f+ek+r 
  EEA18606.1  43 AYNIRHLPNPPR--QLRvNATGMSRRLQKEFLQNDNVEAFLEKVRG 86 
                 6789******75..55524799999998888888999***999875 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 3.5e-05
                 EEEEEEESSSSSHHHHHHHHHHH CS
  ATP_bind_2 243 ltiaiGctGGkhrsvaiaeqlad 265
                 ++++i c  G+hrsva  e+la 
  EEA18606.1 137 IVVTICCEEGRHRSVAFVEELAR 159
                 799*****************986 PP

>> DUF1948  Domain of unknown function (DUF1948)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.1   4.1e-06     0.015      27      71 ..      66     110 ..      60     143 .. 0.91

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 4.1e-06
                 HHHHHHHHT--TTT---HHHHHHHHHHHHHHHHHHHHHHHHHHH- CS
     DUF1948  27 viqadfleydvkerqlnewqkeivkvfserivefikkieeqqlkn 71 
                  +q +fl+ d  e  l++ + ei ++  e++ +f + ieeq++ +
  EEA18606.1  66 RLQKEFLQNDNVEAFLEKVRGEICNAVNEECGQFLNFIEEQDQSK 110
                 6899************************************98764 PP

>> DUF5097  Domain of unknown function (DUF5097)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.1   1.9e-05     0.069      18      69 ..      51     102 ..      44     141 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 1.9e-05
     DUF5097  18 nstkdlkelsasivkilsskFlinEkvfikkkekyGrivnlvkkeytvvihn 69 
                 n  ++l+  ++ + ++l+++Fl+n++v    ++  G+i n v++e+   ++ 
  EEA18606.1  51 NPPRQLRVNATGMSRRLQKEFLQNDNVEAFLEKVRGEICNAVNEECGQFLNF 102
                 66677888889999*******************************9776633 PP

>> DnaI_N  Primosomal protein DnaI N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.1   2.9e-05       0.1      22      79 ..      65     126 ..      55     140 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 2.9e-05
                 HHHHHHHTTXHHHHHHHHHSTTTC-HHHHHHTHHHHHHHHHS-SS-TT.....TTS--SSTTE CS
      DnaI_N  22 eklkeevlsdpeVqaFlqehqeelteeaierslskLyeyveekkkcea.....eecknlakGY 79 
                 ++l +e l++ +V+aFl++ + e+ + a++++  ++ +++ee+++ ++      +++++++ +
  EEA18606.1  65 RRLQKEFLQNDNVEAFLEKVRGEICN-AVNEECGQFLNFIEEQDQSKRggseeTDQHSVLNAH 126
                 67899****************98865.7999**************999776555555555555 PP

>> GldM_C  GldM C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0     5e-05      0.18      67     121 ..      34      88 ..      27     138 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 5e-05
      GldM_C  67 gkgnkigsftFrVkkiPdPtaeirgekkggsaiskrsllaaagidasledfllda 121
                 ++ +  ++  ++++ +P P  ++r++ +g+s   ++++l++++++a le+   ++
  EEA18606.1  34 NEARYHKTLAYNIRHLPNPPRQLRVNATGMSRRLQKEFLQNDNVEAFLEKVRGEI 88 
                 6677788999***************999998899999999*****9999866555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (229 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       634  (0.0353617); expected 358.6 (0.02)
Passed bias filter:                      427  (0.0238162); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.61u 0.35s 00:00:00.96 Elapsed: 00:00:00.55
# Mc/sec: 1242.69
//
Query:       EEA18607.1  [L=548]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.3e-11   42.2   0.5    4.1e-10   39.0   0.1    2.0  2  Fungal_trans_2  Fungal specific transcription factor domain
    9.1e-08   32.1  11.0      2e-07   31.0  11.0    1.6  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.011   15.9   0.0        0.4   10.8   0.0    2.3  2  SIR2_2          SIR2-like domain


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.0   0.1   6.8e-14   4.1e-10       3     177 ..     114     285 ..     113     314 .. 0.86
   2 ?    1.4   0.1     0.018   1.1e+02     308     340 ..     430     462 ..     393     481 .. 0.74

  Alignments for each domain:
  == domain 1  score: 39.0 bits;  conditional E-value: 6.8e-14
  Fungal_trans_2   3 ldyyldnvapllspvpessnpfrkvllplalsnkallhallalsafhlqskgpkds.lereakrykslalkelqealaelsstls....rnekyk 92 
                     l+++ + +a+l+  + +  + ++ ++ +l ++ +a+ +a++a+sa++   ++++++  + ++     l+lk+ ++a+a l++ l       ++ +
      EEA18607.1 114 LHFFRNATARLCGAYFHD-EFWHGLVHQLSEEQPAVRYAVIAMSARQA--QFEREQlQQATKSEQELLSLKQCNKAIASLRNFLVkeppGAARNQ 205
                     566777777777776665.99************************877..555555245555566666*****************99*9999999 PP

  Fungal_trans_2  93 diLaaiLllcsieissgdvsdwrvhLeaatsliksrggskasssslsskarfllrifayldilssttlgrgpsfpseeyekllen 177
                      +La++ +l+    ++ d +   +h++   +l++ +++    +++ ss a+ l+r fa l +  st+++  p+   ee  ++l++
      EEA18607.1 206 VVLATCAVLVYLALFEDDTKVADYHFQSGYRLLQEWRKD---DFNGSSSAPALVRTFAQLQLHRSTCTN--PKVFVEEDDPILSS 285
                     9**************************************...*************************99..87777777776666 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.018
  Fungal_trans_2 308 aiasLlWplFiaGceavdeddRdfvrrrleele 340
                     a ++L+ pl+ +G  + d + R+ v ++l+el 
      EEA18607.1 430 ARVVLIPPLLFCGFKCRDWQVRRQVMQLLQELR 462
                     4778999**********************9997 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.0  11.0   3.3e-11     2e-07       1      35 [.      26      60 ..      26      65 .. 0.89

  Alignments for each domain:
  == domain 1  score: 31.0 bits;  conditional E-value: 3.3e-11
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCT CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfyse 35
                ++C +C++++ KCd+++P+C++C+ ++ eC+ y  
  EEA18607.1 26 TGCLTCKRRHKKCDENRPSCRRCIASGRECEGYYT 60
                58****************************98765 PP

>> SIR2_2  SIR2-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0     0.024   1.5e+02      83     134 ..     115     166 ..     104     175 .. 0.71
   2 ?   10.8   0.0   6.7e-05       0.4      88     116 ..     436     464 ..     404     481 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.024
      SIR2_2  83 allrskslLflGySfsDpnirelleellkesgnarrhyaflpede..keeeekl 134
                 +++r+ +  ++G  f D+  + l+++l +e++     ya+++ ++   + e+++
  EEA18607.1 115 HFFRNATARLCGAYFHDEFWHGLVHQLSEEQPA--VRYAVIAMSArqAQFEREQ 166
                 56677777789999*******************..5555554444322333333 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 6.7e-05
      SIR2_2  88 kslLflGySfsDpnirelleellkesgna 116
                  +lLf+G+  +D+++r  + +ll+e +++
  EEA18607.1 436 PPLLFCGFKCRDWQVRRQVMQLLQELRDH 464
                 589*********************99983 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (548 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       630  (0.0351386); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.74u 0.30s 00:00:01.04 Elapsed: 00:00:00.54
# Mc/sec: 3049.69
//
Query:       EEA18608.1  [L=420]
Description: formaldehyde dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.5e-28   97.3   1.4    9.2e-28   96.3   1.4    1.4  1  ADH_N         Alcohol dehydrogenase GroES-like domain
      3e-10   40.2   0.0    7.4e-05   22.7   0.0    2.3  2  ADH_zinc_N    Zinc-binding dehydrogenase
  ------ inclusion threshold ------
      0.029   13.8   0.0      0.056   12.8   0.0    1.5  1  2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, 


Domain annotation for each model (and alignments):
>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   96.3   1.4   1.5e-31   9.2e-28       3     106 ..      63     186 ..      62     189 .. 0.89

  Alignments for each domain:
  == domain 1  score: 96.3 bits;  conditional E-value: 1.5e-31
                 EEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS--TT-EEEE-SEEE-SSSHHHHTT-GGG-...............TTBEE CS
       ADH_N   3 evlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkklkvGdrVvvepliscgeCaaCkegeenlC...............eeakl 86 
                 +++++++ ++iCgsDl i++g+ + +++ + i+GHE++G ve+vg++v++lkvGdrV++ p+i+cg+C++Ck++++ lC               +  ++
  EEA18608.1  63 DAIVRITHTTICGSDLYIYEGDLDRSMEKGRIMGHEAIGFVEKVGSAVSRLKVGDRVIILPIIACGQCQYCKKQQYALCdttngseemeakyghRLSGT 161
                 689*******************9**********************************************************999998888877633344 PP

                 TTTS.....S-SSSBSEEEECGGGE CS
       ADH_N  87 lgvs.....ldGgfaeyvvvpekkl 106
                 lg s     ++G +aey+ vp+++l
  EEA18608.1 162 LGSSelmggYSGDQAEYCRVPNADL 186
                 444477777899********98776 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   0.0   1.2e-08   7.4e-05       1      71 [.     232     301 ..     232     309 .. 0.87
   2 !   15.0   0.0     3e-06     0.018      69     115 ..     320     368 ..     316     392 .. 0.82

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 1.2e-08
                 HHHHHHHHHHHHTT-.EEEEEESSHHHHHHHHHTT...ESEEEETTTCHHHHHHHHHTTTSSEEEEEESSCSHHH CS
  ADH_zinc_N   1 gvGlaavqlAkalGa.eviavdsseeklelakklG...adevinykeadlverikeltggegvdvvfecvGsgat 71 
                 +vGl    lAk  Ga +v+avd ++ +l++a+++G   +d+v ++   +++ +i +   + g+d  +e++G  ++
  EEA18608.1 232 AVGLSIQRLAKLRGAsKVFAVDKDQTRLQIAESFGmipVDVVAHP---NVSNYILSVQ-PHGLDCGIEASG-FRS 301
                 6999*******************************6555777777...8999999999.889999999999.555 PP

  == domain 2  score: 15.0 bits;  conditional E-value: 3e-06
                 HHHHHHHHHCEEEEEEEEECSC.TSSEEEEEHHHHHHTT-EEEE.E-SS CS
  ADH_zinc_N  69 gatleaalkllkpgGrlvvvGg.gkgeeefdlrnlllkeksilG.sllg 115
                 g+t+ a lk++++gG +++ G  + g ++f++++l+ k ++++G  ++g
  EEA18608.1 320 GDTVHAVLKSTRKGGHIALTGDfFWGTNDFPIGMLMEKGITVRGgQHFG 368
                 799******************99999999*************8614555 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   9.4e-06     0.056      34      78 ..     220     265 ..     201     288 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 9.4e-06
                   GTTSEEEEES-SHHHHHHHHHHHHTT-.EEEEESSSHHHHHCHHHH CS
  2-Hacid_dh_C  34 lsgktvGiiGlGrIGqavakrlkafgm.kviaydrskkkeeeeeel 78 
                    +g  vG++G+G++G ++ +++k  g+ kv+a+d+ +++ + +e+ 
    EEA18608.1 220 GKGDIVGVWGCGAVGLSIQRLAKLRGAsKVFAVDKDQTRLQIAESF 265
                   46889******************88887******998866655554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (420 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       623  (0.0347482); expected 358.6 (0.02)
Passed bias filter:                      527  (0.0293937); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.32s 00:00:00.85 Elapsed: 00:00:00.51
# Mc/sec: 2487.63
//
Query:       EEA18609.1  [L=789]
Description: exo-beta-1,3-glucanase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      9e-91  303.5  17.7    8.7e-82  274.1   5.9    2.9  4  Pectate_lyase_3  Pectate lyase superfamily protein
    5.8e-07   29.1   1.3      0.031   14.0   0.1    2.6  2  End_N_terminal   N terminal extension of bacteriophage endosi


Domain annotation for each model (and alignments):
>> Pectate_lyase_3  Pectate lyase superfamily protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  274.1   5.9   9.7e-86   8.7e-82       1     214 [.      72     295 ..      72     296 .. 0.97
   2 ?   -3.0   0.1      0.62   5.5e+03      33      43 ..     356     366 ..     353     369 .. 0.82
   3 !   37.6   0.3   2.2e-13     2e-09       5      75 ..     427     494 ..     423     549 .. 0.84
   4 ?   -3.7   0.0         1     9e+03     120     165 ..     582     632 ..     561     639 .. 0.63

  Alignments for each domain:
  == domain 1  score: 274.1 bits;  conditional E-value: 9.7e-86
                      SEEGGGGT---EEEEE-HHHHHHHH...............HTSS-EEE-SEEEEESS-EEE-SSEEEEES-TTTEEEEE-TT-SS--SEEES-T CS
  Pectate_lyase_3   1 frnVkdyGakgDGvtDdtaaiqkais.........casatttgavVYfPaGtYlvsspiilksgvqLvGdgngrpvlkaaaafvgaglidgdpy 85 
                      frnVkdyGa+gDGvtDdt ai++ais          ++++tt+a++YfPaGtY+vss+ii+++ +qL+G++n ++vlka+++fvg glidgd+y
       EEA18609.1  72 FRNVKDYGAVGDGVTDDTLAINNAISdggrfgpasRQTSSTTPAIIYFPAGTYVVSSSIINYYFTQLIGNPNSPAVLKATPGFVGLGLIDGDQY 165
                      8**********************************9********************************************************** PP

                      TT-..-EEEEEEEEEEEGGGG-SS---S..SEEE..ES-EEEEEEEEEEES-SSEEE-SSS---TT---SS--EEEEES-EEES-SS-SEEES- CS
  Pectate_lyase_3  86 vsggsealiatnnfyrqirnlkiditav..apga..tgihwqtaqatslenvefemseasgtkhqgifiengsggflndlvfsglgdigiavgn 175
                      + +g++++i+tn+fyrqirnl++d ta+  +  +  tgihw+t+qatsl+nv+++++ + gtk qg+fiengsggfl+d++++g g +g++vgn
       EEA18609.1 166 QPDGNQGWISTNVFYRQIRNLILDLTAIpaS--GgsTGIHWPTGQATSLQNVQIKLNADPGTKAQGLFIENGSGGFLTDVIVTG-GLYGFNVGN 256
                      *8889***********************644..446************************************************.********* PP

                      EEEEEES-EEE-S--SEEE-TT-EEEEEEEEEESSSEEE CS
  Pectate_lyase_3 176 qqftvrnitfnnattgievlwgwgwtlknvkinncegGi 214
                      qqft+rn+t+++a  +i++ w+wgwt+++++i+nc++ +
       EEA18609.1 257 QQFTMRNVTISSAVVAISQIWNWGWTYSGLTIENCQTAF 295
                      ***********************************9976 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.62
                      TSS-EEE-SEE CS
  Pectate_lyase_3  33 tgavVYfPaGt 43 
                      ++  VY+P Gt
       EEA18609.1 356 GPNGVYLPGGT 366
                      6788******9 PP

  == domain 3  score: 37.6 bits;  conditional E-value: 2.2e-13
                      GGGT---EEEEE-HHHHHHHH......HTSS-EEE-SEEEEESS-EEE-SSEEEEES-TTTEEEEE-TT-S CS
  Pectate_lyase_3   5 kdyGakgDGvtDdtaaiqkaiscasatttgavVYfPaGtYlvsspiilksgvqLvGdgngrpvlkaaaafv 75 
                      + +GakgDGvtDdt +iq+++  + a + g++ +f  G Y+v+++i ++ g   vG++  +++l   ++f 
       EEA18609.1 427 RVFGAKGDGVTDDTIIIQAVL--NVAAALGKIAFFDYGVYVVTNTIYIPPGSRVVGEA-YPTILGSGSKFS 494
                      669******************..99********************************9.555555555444 PP

  == domain 4  score: -3.7 bits;  conditional E-value: 1
                      -EEE.EEEEEEEES-SSEEE-SSS..---TT---SS--EEEE..ES-EEES CS
  Pectate_lyase_3 120 ihwq.taqatslenvefemseasg..tkhqgifiengsggfl..ndlvfsg 165
                      +h++ +a+++ len+ +   +++    k ++i +  g g  +  +++ ++g
       EEA18609.1 582 LHVTsSAKNVYLENNWIWTADHDLddPKDTRISVYTGRGALIegSNILMYG 632
                      453337777777777775555554333444666666666666666666666 PP

>> End_N_terminal  N terminal extension of bacteriophage endosialidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.0   0.1   3.4e-06     0.031       1      19 [.      80      98 ..      80     104 .. 0.92
   2 !   13.5   0.1     5e-06     0.045       1      25 [.     431     455 ..     431     461 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 3.4e-06
                    ---EEEEE-HHHHHHHHHH CS
  End_N_terminal  1 akGDGvtdDtdalsevlaa 19
                    a+GDGvtdDt a+++++++
      EEA18609.1 80 AVGDGVTDDTLAINNAISD 98
                    89**************997 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 5e-06
                     ---EEEEE-HHHHHHHHHHS-TTS- CS
  End_N_terminal   1 akGDGvtdDtdalsevlaaapvgkk 25 
                     akGDGvtdDt  +++vl++a++  k
      EEA18609.1 431 AKGDGVTDDTIIIQAVLNVAAALGK 455
                     89****************9876555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (789 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       320  (0.0178482); expected 358.6 (0.02)
Passed bias filter:                      250  (0.0139439); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.30s 00:00:00.94 Elapsed: 00:00:00.48
# Mc/sec: 4968.45
//
Query:       EEA18610.1  [L=214]
Description: extracellular thaumatin domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (214 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       321  (0.017904); expected 358.6 (0.02)
Passed bias filter:                      267  (0.0148921); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.46
# Mc/sec: 1404.89
//
Query:       EEA18611.1  [L=178]
Description: hypothetical protein PMAA_008990 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (178 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       414  (0.0230911); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.41u 0.25s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1317.97
//
Query:       EEA18612.1  [L=185]
Description: hypothetical protein PMAA_009000 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        0.1   12.3   0.0       0.15   11.7   0.0    1.3  1  DDE_2     Bacteriophage Mu transposase


Domain annotation for each model (and alignments):
>> DDE_2  Bacteriophage Mu transposase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   8.6e-06      0.15      85     161 ..      51     123 ..      43     141 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 8.6e-06
                 TTTTS---TTTTBS-..B----HHHHHHHHTEEEESSSB-TTTTT-BSS-SSGGGSGGGGCTTTTT-GGGTTTB--S-S CS
       DDE_2  85 nkkltggvknryryk..vkedevkglilllgiklhwtsvvagkgrgqakpverafsvggleeyvdkhlllagayagana 161
                 +k+ +gg++  y ++  ++++++k +il   i +  t v    g      v       g+++y d   +l g+y ga +
  EEA18612.1  51 QKYASGGADLAYMFRanIQNENTKEIILQALISMGMTEVSQYLG------VTIEVDASGIGQYADSFFALLGTYHGAGP 123
                 57788999988877622668889999999999**9999976555......34446678******************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (185 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       410  (0.022868); expected 358.6 (0.02)
Passed bias filter:                      381  (0.0212505); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.25s 00:00:00.67 Elapsed: 00:00:00.41
# Mc/sec: 1356.78
//
Query:       EEA18613.1  [L=82]
Description: hypothetical protein PMAA_009010 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (82 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       703  (0.0392102); expected 358.6 (0.02)
Passed bias filter:                      400  (0.0223102); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.30s 00:00:00.81 Elapsed: 00:00:00.51
# Mc/sec: 487.75
//
Query:       EEA18614.1  [L=548]
Description: puromycin resistance protein pur8, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    9.2e-36  123.5  36.6    9.2e-36  123.5  36.6    1.7  2  MFS_1       Major Facilitator Superfamily
    5.4e-12   44.9  10.0    7.6e-12   44.4  10.0    1.1  1  TRI12       Fungal trichothecene efflux pump (TRI12)
     0.0031   16.4   4.3     0.0031   16.4   4.3    2.5  3  MFS_1_like  MFS_1 like family
     0.0081   14.5   0.5     0.0081   14.5   0.5    2.0  3  OATP        Organic Anion Transporter Polypeptide (OATP) fami
  ------ inclusion threshold ------
        0.1   12.6   0.0        6.2    6.9   0.0    2.4  2  PA          PA domain


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.5  36.6   2.6e-39   9.2e-36       2     348 ..      86     482 ..      85     487 .. 0.86
   2 ?   -4.2   0.2       1.7   6.1e+03     136     150 ..     524     538 ..     517     539 .. 0.57

  Alignments for each domain:
  == domain 1  score: 123.5 bits;  conditional E-value: 2.6e-39
       MFS_1   2 llaaflsalarsilgpalplalaedlgispse.igllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll.fasslw.lllvlrvlqGl 97 
                 +++a+++a+++ il+p+lp  ++  ++++ps    + +t+y l+ a ++ +  ++++ fGrr +l++gl++f  g l+l+  +++l+ +llv+r++qG+
  EEA18614.1  86 AIMAMMVAMDALILIPILP-KITGKYHSNPSRdTMWPMTVYILANATFQRFHVAVMEIFGRRNMLIAGLIVFTMG-LILIsASPPLFpILLVGRAVQGA 182
                 78999**************.*******999998999***************************************.555524488998*********** PP

       MFS_1  98 gagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee........ 188
                 ga+a++++  a++ d+ p+++r++++  + +++++Gailg  lgg+++ + +W ++fyi+a++++l+fv+  l +  +p+ ++ +++k+ +        
  EEA18614.1 183 GAAAMVSIPPAMLMDMIPERRRSMYNFAIILSSAIGAILGLTLGGIFIRQDSWKWIFYIAAPFCFLLFVITPLAV--RPVGESLEPKKR-Lmkvdwtgs 278
                 *******************************************************************99644444..222222222222.235679999 PP

       MFS_1 189 ..............................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlgls 241
                                                                + + +pl++ +++l+ +p   + ++++l+ ++ ++  l+ lp yl  v++ s
  EEA18614.1 279 flfsgsmtslllgltwatslnkelklkvlvalgagavgmivtmlyeRSGASRPLLS-LGILRVSP---LTFLCVLIQSLLIAVQLVCLPAYLGGVHDSS 373
                 *********************************************9999999****.********...3777777778899999*************** PP

       MFS_1 242 glllaglllallalvgailallagrlsdr.....lgrrrrlllallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdlappeeag 335
                    ++++++ ++++v+   +ll++  +d      +  r++l+++ +l ++++++l  +++ ++  ++++v+++ G+g+g++ ++  +++ +l  ++ + 
  EEA18614.1 374 --STTTGAILIPMIVT---MLLVTGGIDIvptklYRYRWPLWFGWALNIASSASLTTFNTHTTLRVCIIVMLVTGLGHGITISATHTALRELSRQRSRS 467
                 ..56666799999999...555555567755556777***********************************************999999998654444 PP

       MFS_1 336 ..tasglfntagslg 348
                    a  ++n+++++g
  EEA18614.1 468 qrDACLIANFVRTAG 482
                 334555555555555 PP

  == domain 2  score: -4.2 bits;  conditional E-value: 1.7
       MFS_1 136 lgpllggllasslgW 150
                 + +++ggll+  +gW
  EEA18614.1 524 ILAGFGGLLSLFVGW 538
                 444555555555555 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.4  10.0   2.1e-15   7.6e-12      75     329 ..     108     362 ..      50     370 .. 0.71

  Alignments for each domain:
  == domain 1  score: 44.4 bits;  conditional E-value: 2.1e-15
       TRI12  75 gqsensslfstlwtt.....gqavsilvmgrltdrfgrrpfvilthilglvgaiv.gctatkfntllaamtllgvaagpaga.splfvgelmsnktkfl 166
                 g+   +    t+w +      +a        + + fgrr ++i+  i+  +g i+  ++   f  ll   ++ g  a    +  p ++ +++ ++ + +
  EEA18614.1 108 GKYHSNPSRDTMWPMtvyilANATFQRFHVAVMEIFGRRNMLIAGLIVFTMGLILiSASPPLFPILLVGRAVQGAGAAAMVSiPPAMLMDMIPERRRSM 206
                 44444444455554400000444444445567899*****************986155667899*****999998666555416788889998887776 PP

       TRI12 167 gllivsipvvvtsglspylgqrlaiqgswrwifyiyiitsaiavllivvwyyppsfaqlhgkkvrkreelakldwigiilvivgvslfllgvswggkpn 265
                   + + +   + + l+  lg  +  q sw+wifyi    +  + ll v+    p   +  g   + ++ l k+dw g +l +  ++ +llg++w    n
  EEA18614.1 207 YNFAIILSSAIGAILGLTLGGIFIRQDSWKWIFYIA---APFCFLLFVI---TPLAVRPVGESLEPKKRLMKVDWTGSFLFSGSMTSLLLGLTWATSLN 299
                 6555555555555688999*9999**********74...5566666665...34445556899999999****************************99 PP

       TRI12 266 spwnsakviglissglgslvvfalyevygkpvrpivppalfkdt.rgfvcillissimgamnlsl 329
                 +  +  kv+  + +g+  ++v  lye  g   rp++   +++ +   f+c+l+ s ++    ++l
  EEA18614.1 300 KELK-LKVLVALGAGAVGMIVTMLYERSGA-SRPLLSLGILRVSpLTFLCVLIQSLLIAVQLVCL 362
                 9886.57777788888889999****9996.6899998888754279***998776665544454 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1      0.22     8e+02      65      86 ..      80     101 ..      70     120 .. 0.70
   2 !   16.4   4.3   8.6e-07    0.0031     268     384 ..     124     240 ..     111     241 .. 0.88
   3 ?   -1.4   0.1      0.23   8.3e+02     314     352 ..     437     475 ..     413     489 .. 0.62

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.22
  MFS_1_like  65 kkvvilslllsavlflsllfip 86 
                   vv +++++ +v++ +l++ip
  EEA18614.1  80 SMVVCFAIMAMMVAMDALILIP 101
                 5688888888888888898888 PP

  == domain 2  score: 16.4 bits;  conditional E-value: 8.6e-07
  MFS_1_like 268 lgvvaeiplfffaeklleklGhvklliiallayilrfllyaii.enawlvlpievLhgisfgllwaaaveyvskiapksleatgqgllsglyfglGral 365
                 +  +a+ ++  f   ++e++G +++li++l+++++ ++l+++    + ++l+  + +g+  +++ ++      +++p++ ++ +  +  +l+  +G  l
  EEA18614.1 124 VYILANATFQRFHVAVMEIFGRRNMLIAGLIVFTMGLILISASpPLFPILLVGRAVQGAGAAAMVSIPPAMLMDMIPERRRSMYN-FAIILSSAIGAIL 221
                 3446666777788899***************************999999999***************************999885.66788999***** PP

  MFS_1_like 366 GsliGGllwdlksaiflFr 384
                 G  +GG+++ ++s +++F+
  EEA18614.1 222 GLTLGGIFIRQDSWKWIFY 240
                 *********9999999996 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.23
  MFS_1_like 314 wlvlpievLhgisfgllwaaaveyvskiapksleatgqg 352
                  ++l++ + hgi++ +++ a+ e +++    +  a +++
  EEA18614.1 437 IVMLVTGLGHGITISATHTALRELSRQRSRSQRDACLIA 475
                 344555555888888888888888887777777777666 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.5   2.3e-06    0.0081     133     193 ..     163     231 ..      80     237 .. 0.66
   2 ?   -2.5   0.7      0.32   1.2e+03     331     352 ..     372     393 ..     343     442 .. 0.70
   3 ?   -2.1   0.4      0.24   8.6e+02      66      72 ..     408     414 ..     370     529 .. 0.66

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 2.3e-06
                 x........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 133 l........lfflaqlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllk 193
                 +        +++++  ++G+Ga++++++  + + D + +++ ++y  +++  +++G +lG +lG+++++
  EEA18614.1 163 IsaspplfpILLVGRAVQGAGAAAMVSIPPAMLMDMIPERRRSMYNFAIILSSAIGAILGLTLGGIFIR 231
                 0344444449************************************99*****************9976 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.32
                 xxxxxxxxxxxxxxxxxxxxxx RF
        OATP 331 eAnlltGvvvipgaalGillgG 352
                 ++++ tG+++ip++++ +l+ G
  EEA18614.1 372 SSSTTTGAILIPMIVTMLLVTG 393
                 4455667777776666655544 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 0.24
                 xxxxxxx RF
        OATP  66 Prwigig 72 
                 P w g++
  EEA18614.1 408 PLWFGWA 414
                 3444444 PP

>> PA  PA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0     0.028        99      39      54 ..     176     191 ..     151     210 .. 0.83
   2 ?    6.9   0.0    0.0017       6.2      36      57 ..     303     324 ..     257     341 .. 0.79

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.028
          PA  39 arnAqaaGAagviivn 54 
                  r++q aGAa+++ + 
  EEA18614.1 176 GRAVQGAGAAAMVSIP 191
                 5799********9874 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0017
          PA  36 aeKarnAqaaGAagviivndge 57 
                 + K+ +A  aGA+g+i+    e
  EEA18614.1 303 KLKVLVALGAGAVGMIVTMLYE 324
                 67999************95433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (548 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       712  (0.0397122); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.78u 0.36s 00:00:01.14 Elapsed: 00:00:00.56
# Mc/sec: 2952.12
//
Query:       EEA18615.1  [L=449]
Description: capsule polysaccharide synthase Cps1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.4e-16   61.1   0.0      2e-16   60.6   0.0    1.2  1  Glyco_tranf_2_3  Glycosyltransferase like family 2
    3.3e-05   23.4   0.0     0.0012   18.4   0.0    2.1  2  Glyco_transf_21  Glycosyl transferase family 21
    0.00072   19.4   0.0     0.0018   18.1   0.0    1.8  2  Glycos_transf_2  Glycosyl transferase family 2


Domain annotation for each model (and alignments):
>> Glyco_tranf_2_3  Glycosyltransferase like family 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.6   0.0   3.4e-20     2e-16       4     229 ..      73     316 ..      71     317 .. 0.81

  Alignments for each domain:
  == domain 1  score: 60.6 bits;  conditional E-value: 3.4e-20
  Glyco_tranf_2_3   4 lavlVptfneed.vlgevlesllaqeyprvevvvvv.desdaetlevaeelaaalpdvrvrvvvnarnlgstgksralnealravksdlvllvD 95 
                      ++v+Vpt + e  + +e++ s++++  p   ++vv   e   +  +++    +++++ +++  v  r   +  k+  ++ a+++v+++++++ D
       EEA18615.1  73 VTVIVPTVDPENtDFVECILSIISN-KPKKLIIVVPsKEMVNSIKKRLIS-WRICSK-KISMSVL-RAVQV-NKRAQVACAIPHVRTAITIIAD 161
                      89*****998877999999999994.344444444443333444444433.456775.5554322.44444.5777899*************** PP

  Glyco_tranf_2_3  96 dDtvv.ePdtlkrllqffltpkvgavgtpvfl.lnrs.....tlvsalgalefaerhlrflaarralgvltln.Gsgslirrevlkele..... 176
                      d + + +P++l  +l+ f++p+vgavgt++++ + ++     +++++lga+++++ +++++a+    g +++n G++s+ r+++l+ +      
       EEA18615.1 162 DHVFWrSPRFLSTILAPFEDPRVGAVGTNKRAiRAEKgfttaAFWNMLGAIYLERQDFDVRATNALDGGVFVNsGRTSAHRTSILQSPNflegy 255
                      ******************************88444554554455******************9999998888879******************* PP

  Glyco_tranf_2_3 177 ........gldplflltdDyelglrlrragfrtay..vpgaavrevfpsslkayikqrnRwvy 229
                              +++p  +  dD+ ++++  r+g+ +++  +p+ ++++  +++  +y  q+ Rw++
       EEA18615.1 256 lnerfffgLFGP-LNCDDDNYITRYEVRYGWNIKIqhCPHGLMETPLGTY-PKYLSQCLRWAR 316
                      *****9988999.999*****************98779999888887755.579*******97 PP

>> Glyco_transf_21  Glycosyl transferase family 21
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.0   1.9e-07    0.0012      15     114 ..     139     247 ..     129     254 .. 0.73
   2 ?    2.8   0.0     0.012        71     128     173 .]     272     316 ..     263     316 .. 0.85

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 1.9e-07
  Glyco_transf_21  15 vnpKvnnllqaleaakydllvisDsdvrvk.pdyLeellaaledpkvglVtslpvgsdakg......laaaleaafl..ntl.agvlqakls.g 97 
                      vn +  ++++a++ +++ +++i+D+ v+ + p +L ++la++edp+vg V    ++ +a++      +++ l a +l  + +  +++ a l  g
       EEA18615.1 139 VNKRA-QVACAIPHVRTAITIIADDHVFWRsPRFLSTILAPFEDPRVGAVGTNKRAIRAEKgfttaaFWNMLGAIYLerQDFdVRATNA-LDgG 230
                      55555.899999***************985389*****************998887777644555556666666666543332444444.6414 PP

  Glyco_transf_21  98 lgfavGksmalrreaLe 114
                      +    G + a r+++L+
       EEA18615.1 231 VFVNSGRTSAHRTSILQ 247
                      44445777777777776 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.012
  Glyco_transf_21 128 eDyalgkllraaGlkvvlspapiaqtsvprrsslrallaRqlrWar 173
                      +D  ++++  + G+++ + + p   +++p   ++ ++l++ lrWar
       EEA18615.1 272 DDNYITRYEVRYGWNIKIQHCPHGLMETPL-GTYPKYLSQCLRWAR 316
                      788888888899999999999977777775.68999********97 PP

>> Glycos_transf_2  Glycosyl transferase family 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0     3e-07    0.0018       1     147 [.      74     218 ..      74     248 .. 0.75
   2 ?   -3.4   0.0       1.2   7.4e+03      97     118 ..     386     407 ..     384     411 .. 0.79

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 3e-07
                      EEEEEESS-.TTTHHHHHHHHHHHGGCCEEEEEEEEES-.SSCHHHHHGGGCH..C-TTEEEEEESSS-HHHHHHHHHHHH--SSEEEEEESSE CS
  Glycos_transf_2   1 svviptyNe.ektlletlesllaqdpypdfeiivvDDgS.tDetveileelak..edprvrvirreenvGkagalnaglraatgdyilflDaDd 90 
                      +v++pt         e++ s++++  +p++ iivv   +   + ++ l +++   ++    v+r    v k + + +++ ++++ + ++ D+++
       EEA18615.1  74 TVIVPTVDPeNTDFVECILSIISN--KPKKLIIVVPSKEmVNSIKKRLISWRIcsKKISMSVLRAV-QVNKRAQVACAIPHVRTAITIIADDHV 164
                      699999999888899********9..8888899998888555666666666666444455555555.55************************* PP

                      EE-TT.HHHHHHHHHHH.TTCEEEEEEEEEECCCCCCCHC-SSEEEECCHCCCCHCCC CS
  Glycos_transf_2  91 epdpd.wleklvealekdgadvvlgqrprifgetdeiernkrvgenerlyfkerkrsl 147
                       +    +l+ +++++e++++++v  + ++i+ e+++ + +    ++++l     +r++
       EEA18615.1 165 FWRSPrFLSTILAPFEDPRVGAVGTNKRAIRAEKGFTTAA----FWNMLGAIYLERQD 218
                      **8777***********88877777777777777776665....45555555444444 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 1.2
                      HHHHHHHHHH.TTCEEEEEEEE CS
  Glycos_transf_2  97 leklvealekdgadvvlgqrpr 118
                      l kl+ ++ ++++d+++   ++
       EEA18615.1 386 LVKLIPYFLRHPKDLIFLPGYY 407
                      6789999999999998876655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (449 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       497  (0.0277205); expected 358.6 (0.02)
Passed bias filter:                      310  (0.0172904); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.70u 0.33s 00:00:01.03 Elapsed: 00:00:00.56
# Mc/sec: 2432.99
//
Query:       EEA18616.1  [L=714]
Description: hypothetical protein PMAA_009040 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.5e-53  181.8   0.1      2e-53  181.4   0.1    1.1  1  adh_short_C2   Enoyl-(Acyl carrier protein) reductase
    1.2e-44  152.1   0.0    1.8e-44  151.6   0.0    1.2  1  adh_short      short chain dehydrogenase
      1e-15   58.1   0.4    3.6e-15   56.3   0.4    2.0  1  T5orf172       T5orf172 domain
    3.4e-10   40.5   0.2    9.4e-10   39.0   0.2    1.8  1  MUG113         Meiotically up-regulated gene 113
    3.4e-05   23.8   0.0    6.5e-05   22.9   0.0    1.4  1  KR             KR domain
    0.00014   21.3   0.0    0.00022   20.7   0.0    1.2  1  GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
    0.00026   20.6   0.1    0.00053   19.5   0.1    1.7  1  Epimerase      NAD dependent epimerase/dehydratase family
    0.00032   20.1   0.0    0.00056   19.4   0.0    1.4  1  DUF1776        Fungal family of unknown function (DUF1776)


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  181.4   0.1   8.7e-57     2e-53       1     234 []     460     705 ..     460     705 .. 0.94

  Alignments for each domain:
  == domain 1  score: 181.4 bits;  conditional E-value: 8.7e-57
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGH.HHHHHHHHHHTTSE.E..EE--TTSHHHHHHHHHHHHHHH.SSEEEEEE-----EG.CSS-GGGH- CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneea.kkrveelaeelgae.v..lecDVtdeeqvealveevvekf.gklDilvnnagiapk.lkgpflets 91 
                   Gaa+gIGr++ ++l ++G +v l+d n+ + +++++ la+ ++++ +  + cD  ++++++ ++e++ + f g+lD+lvnna+++ +   +pf+e+s
    EEA18616.1 460 GAARGIGRGLSRLLLQKGHNVFLVDNNKTElDHTIKHLAATTPNSnYstVICDLCEPAEIKVAIEKAGKFFnGRLDVLVNNAAYTGAvGGTPFAELS 556
                   9*****************************9**********99665567**************************************99******** PP

                   HHHHHHHHHHHTHHHHHHHHHHHHHCTSC......CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTG..GG CS
  adh_short_C2  92 reefdraldvnlyslfllakaalplmkeg......gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTla..as 180
                    + + + +++nl++++l+++ +lpl+++       gsi+++ss++a+++ pn + y+a+Ka+l++lt+++A +l+ +gi vN++ pg+i+      +
    EEA18616.1 557 LDTWSKSIQTNLTGAMLMSQGCLPLLRKDagrekgGSIIHMSSTRAHQSEPNSEGYAATKAGLIGLTHAMASSLAGDGIAVNVILPGWINVANecKE 653
                   ************************88766678888*******************************************************7763234 PP

                   GSTTHHHHHHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEESTTGG CS
  adh_short_C2 181 gikgfdelleelearaplgrlgtpeevaeaalfLasdeasyitGqtlvvDgGlt 234
                   g + +d l e+ ++++  gr+g++e++ +a+ +L    a+++tG+++vvDgG+t
    EEA18616.1 654 GGEWEDGLSEADHRWHFSGRVGKVEDILRAVEYLTD--AEFVTGTEMVVDGGVT 705
                   4444889***************************87..67************97 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  151.6   0.0     8e-48   1.8e-44       3     185 ..     456     648 ..     454     657 .. 0.96

  Alignments for each domain:
  == domain 1  score: 151.6 bits;  conditional E-value: 8e-48
                 EEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT..TSEEEEEE-TTTSHHHHHHHHHHHHHHH.SSESEEEE---S...S--SSGGG CS
   adh_short   3 vlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee..gakalaiqvDvtdreevealvekavkkl.gkldvLvnNAGi...tgsgpfse 95 
                  l+tGa++GIGr +++ l+++G +v++vd+++ +l +++k+l ++  ++++ ++ +D+ + +e++ ++eka k + g+ldvLvnNA+     g +pf+e
  EEA18616.1 456 FLITGAARGIGRGLSRLLLQKGHNVFLVDNNKTELDHTIKHLAATtpNSNYSTVICDLCEPAEIKVAIEKAGKFFnGRLDVLVNNAAYtgaVGGTPFAE 554
                 59*******************************************99999***********************99***********998878899**** PP

                 CSHHHHHHHHHHHTHHHHHHHHHHHHHHH....HCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSH CS
   adh_short  96 lseeewervievNltgvflltravlpaml....kqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTd 185
                 ls ++w ++i++Nltg++l+++ +lp +     ++++G+I+ +sS+ ++++ ++   Y+A+Ka+++glt+++a  la +gi vn++ PG ++ +
  EEA18616.1 555 LSLDTWSKSIQTNLTGAMLMSQGCLPLLRkdagREKGGSIIHMSSTRAHQSEPNSEGYAATKAGLIGLTHAMASSLAGDGIAVNVILPGWINVA 648
                 ***************************999999999*****************************************************99865 PP

>> T5orf172  T5orf172 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.3   0.4   1.6e-18   3.6e-15       2     103 .]     244     340 ..     243     340 .. 0.77

  Alignments for each domain:
  == domain 1  score: 56.3 bits;  conditional E-value: 1.6e-18
    T5orf172   2 yvYiltnessegetillKIGrtsnvqrRlkelsk..yptkppselevvaekevrkvpnahrvErlihkeLad.rryrvkcdcgkehrEwFevsleevde 97 
                 +vY+++ e+++g    +KIG+++++++R++el+   +  + ++e + +   +  k  na+ +E+ ih+eL + rr+ v++    + +EwFe++ +e+ e
  EEA18616.1 244 HVYTASMEGETGY---VKIGWAEDIEKRIAELNSprQRGTIHNEADTTPGAQ-SKFMNAFYAEQIIHLELYNsRRLAVER----NETEWFEIPTKEAHE 334
                 6999977777777...*****************8773333333433333333.4445***************66666643....59************* PP

    T5orf172  98 vvrriv 103
                 v r+++
  EEA18616.1 335 VCRKWR 340
                 ***996 PP

>> MUG113  Meiotically up-regulated gene 113
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.0   0.2   4.2e-13   9.4e-10       1      77 []     257     339 ..     257     339 .. 0.95

  Alignments for each domain:
  == domain 1  score: 39.0 bits;  conditional E-value: 4.2e-13
      MUG113   1 lKIGrTnnverRlnelnrqcpskltllryyppss......pnahrlErllhleLkd.krlrdekcdcEwFevpaeslkavirkw 77 
                 +KIG ++++e+R++eln+  +++ t++  + +++      +na+  E+ +hleL + +rl  e++  EwFe+p +++ +v rkw
  EEA18616.1 257 VKIGWAEDIEKRIAELNS-PRQRGTIHNEADTTPgaqskfMNAFYAEQIIHLELYNsRRLAVERNETEWFEIPTKEAHEVCRKW 339
                 5****************5.689999******999********************9989999999999***************99 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.0   2.9e-08   6.5e-05       3     161 ..     456     624 ..     455     643 .. 0.79

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 2.9e-08
                 EEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHT..T-EEEE----TT-HHHHHHHHHHHHHHS.S---EEEE--...------ CS
          KR   3 ylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaeleal..gaevevvaaDvsdkdavealleeikaee.ppikGvihaA...gvlrdk 95 
                 +litG++ g+G+ l+r l++kg +  ++   +     + +++i++l+a+  + + ++v +D+ ++++++ ++e++ + + +++   ++ A   g++  +
  EEA18616.1 456 FLITGAARGIGRGLSRLLLQKGHNVFLVDNNK----TELDHTIKHLAATtpNSNYSTVICDLCEPAEIKVAIEKAGKFFnGRLDVLVNNAaytGAVGGT 550
                 69********************8655554444....334446777777655789999*******************999999*9999988333456789 PP

                 -TTT--HHHHHHHHTTTTHHHHHHHHHTTT........S--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHH CS
          KR  96 lleemtaedleqvlapKvkGawnLhelled........esldffvlfSSiagllgsagqanYaaaNaflDalae 161
                 +++e++ +++ + ++  ++Ga  + + + +        e+   ++ +SS  +   ++    Yaa+ a l +l +
  EEA18616.1 551 PFAELSLDTWSKSIQTNLTGAMLMSQGCLPllrkdagrEKGGSIIHMSSTRAHQSEPNSEGYAATKAGLIGLTH 624
                 **********************9999776655556666777778888888888888888888887776655555 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.7   0.0   9.8e-08   0.00022       1      73 [.     457     525 ..     457     542 .. 0.90

  Alignments for each domain:
  == domain 1  score: 20.7 bits;  conditional E-value: 9.8e-08
                    EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHHH CS
  GDP_Man_Dehyd   1 LiTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkgDltDssslerllae 73 
                    LiTG a  iG  l +lLl+kg++v+ +++++++++ ++i+hla       ++n++ + +Dl++ ++++ ++++
     EEA18616.1 457 LITGAARGIGRGLSRLLLQKGHNVFLVDNNKTELD-HTIKHLAATT---PNSNYSTVICDLCEPAEIKVAIEK 525
                    9************************9999988877.899***9754...4689************99988876 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.1   2.4e-07   0.00053       2      77 ..     457     547 ..     456     639 .. 0.78

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 2.4e-07
                 EEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC.........EEEE--TT-HH....HHHHHHHHH..T-SEEEE--S.---H CS
   Epimerase   2 lVtGatGfiGsalvkallekgyevigldrlssasntarledl.........elveldltdrs....alerlfkee..qpdavihlAa.vggv 77 
                 l+tGa+  iG+ l + ll+kg++v  +d+++++  +  ++ l         + v +dl++++    a+e++ k +  + d+ ++ Aa  g v
  EEA18616.1 457 LITGAARGIGRGLSRLLLQKGHNVFLVDNNKTELDHTIKH-LaattpnsnySTVICDLCEPAeikvAIEKAGKFFngRLDVLVNNAAyTGAV 547
                 8*****************************6665554433.3699******99*******99444433333333333677777777766655 PP

>> DUF1776  Fungal family of unknown function (DUF1776)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.0   2.5e-07   0.00056     106     204 ..     550     649 ..     466     668 .. 0.87

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 2.5e-07
     DUF1776 106 gpietiplsswaselnerllspiltlqallplltsra.kqkakiivvnpsissslnlpfhapEalvssalsalfevLkrelrphnidvtqikLGnldla 203
                 +p+++++l++w + ++++l   +l++q+ lpll++ a ++k   i+   s  ++ + p++   a +   l  l+++++ +l+  +i v  i  G +++a
  EEA18616.1 550 TPFAELSLDTWSKSIQTNLTGAMLMSQGCLPLLRKDAgREKGGSIIHMSSTRAHQSEPNSEGYAATKAGLIGLTHAMASSLAGDGIAVNVILPGWINVA 648
                 69********************************99987787788888888888888888888888999999999999999999999999999999999 PP

     DUF1776 204 n 204
                 n
  EEA18616.1 649 N 649
                 7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (714 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       761  (0.0424452); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.82u 0.37s 00:00:01.19 Elapsed: 00:00:00.56
# Mc/sec: 3817.56
//
Query:       EEA18617.1  [L=350]
Description: alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.3e-29   99.8   0.3    1.3e-28   99.0   0.3    1.4  1  ADH_N         Alcohol dehydrogenase GroES-like domain
    5.9e-24   84.5   1.1    9.6e-24   83.8   1.1    1.3  1  ADH_zinc_N    Zinc-binding dehydrogenase
    4.4e-07   31.0   0.1    7.3e-07   30.3   0.1    1.4  1  ADH_zinc_N_2  Zinc-binding dehydrogenase
     0.0097   15.3   0.3      0.017   14.5   0.3    1.3  1  2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, 
  ------ inclusion threshold ------
      0.025   13.9   1.1      0.041   13.2   1.1    1.2  1  AlaDh_PNT_C   Alanine dehydrogenase/PNT, C-terminal domain


Domain annotation for each model (and alignments):
>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.0   0.3   3.7e-32   1.3e-28       1     108 [.      31     139 ..      31     140 .. 0.97

  Alignments for each domain:
  == domain 1  score: 99.0 bits;  conditional E-value: 3.7e-32
                 TTEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS--TT-EEEE-SEEE.-SSSHHHHTT-GGG-TTBEETTTSS-SSSBSE CS
       ADH_N   1 pgevlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkklkvGdrVvveplis.cgeCaaCkegeenlCeeakllgvsldGgfaey 98 
                 p+evl+++k++g+C++Dlh lkg++ l++k p++ GHE +G+v++ g+ v+++++Gd+  +++l   c +C+ Ck+ +e +C++a l g+++dG+f++y
  EEA18617.1  31 PDEVLVNIKYSGVCHTDLHALKGDWPLPTKIPFVGGHEGAGVVVAKGELVNDWEIGDHAGIKWLNGsCLDCEFCKSANEAVCPDALLSGYTVDGTFQQY 129
                 68************************************************************99877******************************** PP

                 EEECGGGEEE CS
       ADH_N  99 vvvpekklvk 108
                 v+ ++++  k
  EEA18617.1 130 VIGKAAHTTK 139
                 **99988776 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.8   1.1   2.7e-27   9.6e-24       1     129 [.     182     312 ..     182     313 .. 0.92

  Alignments for each domain:
  == domain 1  score: 83.8 bits;  conditional E-value: 2.7e-27
                 HHHHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTESEEEETTTC.HHHHHHHHHT.TTSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSCTSSEEE. CS
  ADH_zinc_N   1 gvGlaavqlAkalGaeviavdsseeklelakklGadevinykea.dlverikelt.ggegvdvvfecvGsgatleaalkllkpgGrlvvvGggkgeee. 96 
                 g+G++a q+Aka+G +via+d+ +ek +l++++Ga+++++y++  d+v+++k++t gg g+++v+  + +++ +++a+++++p+G++v +G++ g    
  EEA18617.1 182 GLGSLAQQYAKAMGLRVIAIDGGDEKKALCESMGAEAYVDYTKSkDVVADVKAATpGGLGAHAVLVLAVAEKPFQQATEYVRPRGTVVAIGLPAGAFLk 280
                 89***************************************9889**********66**********999*********************95554423 PP

                 EEHHHHHHTT-EEEEE-SSCHHHHHHHHHHHHH CS
  ADH_zinc_N  97 fdlrnlllkeksilGsllgslreefkealdlla 129
                   ++  + + ++i+Gs +g+ r + +e +d++a
  EEA18617.1 281 AAVFSTVVRMINIKGSYVGG-RLDSEECVDFFA 312
                 7777899*************.999999999876 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.3   0.1     2e-10   7.3e-07       1     133 []     214     346 ..     214     346 .. 0.79

  Alignments for each domain:
  == domain 1  score: 30.3 bits;  conditional E-value: 2e-10
                   TT-SEEEETT.STTHH.....HHH-TT-EEEEEES-H.HHHH.HHHHHHEEEEEEEEE----.S-EEE-CHHHCTTT-EEEE--GGG...-....-H CS
  ADH_zinc_N_2   1 lGAdevidyr.tedfe.....aatggegvDvvldtvg.gealleaslkvlpggGrlvsiggpplsaallkpakkrkgrsvkyeflfsmkas...aqa 87 
                   +GA+  +dy+ ++d++     a  gg g  +vl ++   + + +++ ++++++G++v ig        ++ a+ +     +++ ++ +k s    + 
    EEA18617.1 214 MGAEAYVDYTkSKDVVadvkaATPGGLGAHAVLVLAVaEKPF-QQATEYVRPRGTVVAIGL-------PAGAFLKAAVFSTVVRMINIKGSyvgGRL 302
                   59999******9***999997555567777777774437777.9999***888******95.......34444344455666666666666763333 PP

                   HHHHHHHHHHHHHH----EEEEEEGGGHHHHHHHHHSS--SSEEEE CS
  ADH_zinc_N_2  88 dileelaalieeGklrpvvdrvfpleeaaeAhrylesgrarGKiVl 133
                   d  ee++++++ G ++ +     pl+++++ ++++e+g+++G+ Vl
    EEA18617.1 303 D-SEECVDFFARGLIKAPYK-IAPLKDLPKIFDLMEQGKVVGRYVL 346
                   3.7**************997.9*********************997 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.3   4.7e-06     0.017      36      80 ..     171     216 ..     161     235 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 4.7e-06
                   TSEEEEES-S.HHHHHHHHHHHHTT-EEEEESSSHHHHHCHHHHTC CS
  2-Hacid_dh_C  36 gktvGiiGlG.rIGqavakrlkafgmkviaydrskkkeeeeeelgv 80 
                   g+tv+i+G+G  +G+ + +++ka+g++via+d   +k++ +e++g+
    EEA18617.1 171 GQTVAIVGAGgGLGSLAQQYAKAMGLRVIAIDGGDEKKALCESMGA 216
                   89******9637********************99887765555555 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   1.1   1.1e-05     0.041      26      90 ..     168     233 ..     156     237 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.1e-05
                  B---E.EEEESTS.HHHHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTTCECEEHCHHHHHHHHHHH CS
  AlaDh_PNT_C  26 vepak.vlviGgG.vaGlqAiatakglgakVtvlDvrparleqleslgakfvevlksqeellaeavk 90 
                  ++p++ v ++G+G   G  A + ak++g +V ++D   +++   es+ga+   v + +++ +   vk
   EEA18617.1 168 ARPGQtVAIVGAGgGLGSLAQQYAKAMGLRVIAIDGGDEKKALCESMGAE-AYVDYTKSKDVVADVK 233
                  55554278999752689********************************9.7777766666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (350 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       368  (0.0205254); expected 358.6 (0.02)
Passed bias filter:                      300  (0.0167327); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.50
# Mc/sec: 2101.23
//
Query:       EEA18618.1  [L=620]
Description: hypothetical protein PMAA_009060 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.023   14.8   6.3      0.049   13.7   6.3    1.4  1  bZIP_1    bZIP transcription factor


Domain annotation for each model (and alignments):
>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   6.3   2.8e-06     0.049       6      40 ..     152     183 ..     150     195 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 2.8e-06
                 XXXXX--HHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1   6 rekrkqkNReaArrsRqRKqaeieeLerrvkaLek 40 
                 +e+r+ + R a+r++RqRKq    eL++r+k+L++
  EEA18618.1 152 KERRRTQMRMAQRAYRQRKQN---ELSSRAKQLSE 183
                 79*****************97...57788888875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (620 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1394  (0.0777511); expected 358.6 (0.02)
Passed bias filter:                      564  (0.0314574); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.77u 0.30s 00:00:01.07 Elapsed: 00:00:00.46
# Mc/sec: 4022.76
//
Query:       EEA18619.1  [L=524]
Description: acetyl-coA hydrolase Ach1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.3e-50  171.3   0.0    3.5e-50  170.7   0.0    1.3  1  AcetylCoA_hydro  Acetyl-CoA hydrolase/transferase N-terminal 
    2.3e-43  147.8   0.0    3.4e-43  147.2   0.0    1.3  1  AcetylCoA_hyd_C  Acetyl-CoA hydrolase/transferase C-terminal 


Domain annotation for each model (and alignments):
>> AcetylCoA_hydro  Acetyl-CoA hydrolase/transferase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  170.7   0.0     4e-54   3.5e-50       3     198 .]      14     230 ..      12     230 .. 0.97

  Alignments for each domain:
  == domain 1  score: 170.7 bits;  conditional E-value: 4e-54
  AcetylCoA_hydro   3 eeyekklkepeeaaelvkngshielsgftavgtakaipkylakrkvekenvkkkllidlavgavlsagPeeevleekdavlyrpapkqvgellr 96 
                        y+ kl++pe++++l+ +gs+i++sgft+vg +k +p++la ++vek+n+++kl+  l+vga+  a+  e++++  +++  r  p+qvg+ ++
       EEA18619.1  14 PSYLNKLAKPEDLIDLFPHGSYIGWSGFTGVGYPKKVPTALA-DHVEKNNLEGKLKYSLFVGASSGAE-TENRWARLNMIERR-SPHQVGKEIA 104
                      6799**************************************.********************99999.************99.********** PP

  AcetylCoA_hydro  97 kainqglvsfvdkhlsevpqklekgfvp.......iDvalieataldedGylnlG..vg......vrakKviiEv.......aelvvivvkknp 168
                      k in g ++f+dkhls++p +l +g+++       +Dv+++eata+ edG + +G  vg        a+K iiEv       ++l++i +   p
       EEA18619.1 105 KGINTGNIQFFDKHLSMFPSDLVYGWYTkdrpnkkLDVTVVEATAITEDGGIIPGasVGaspelvQMADKIIIEVntatpsfEGLHDITMSDLP 198
                      *******************************************************666699**977899************************* PP

  AcetylCoA_hydro 169 Prvngydelialdkv..dyivvdpekvvavve 198
                      Pr+++y +l   d++    i+vdpekvva+ve
       EEA18619.1 199 PRRKPYLILSPEDRIgtPHIPVDPEKVVAIVE 230
                      ***************999************97 PP

>> AcetylCoA_hyd_C  Acetyl-CoA hydrolase/transferase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  147.2   0.0   3.8e-47   3.4e-43       1     153 [.     332     482 ..     332     483 .. 0.97

  Alignments for each domain:
  == domain 1  score: 147.2 bits;  conditional E-value: 3.8e-47
                      S-HHHHHHHTT.-TTEEE-BHHHHT-HHHHTTSTTEEEEEE-SEEETTS-EESSEC.TTCCTCGGTTHHHHHHHHHHSTT-EEEEE--SEETTT CS
  AcetylCoA_hyd_C   1 Gskklydflde.npkielrpveyvndpeviaqnkkvvsinsalevdltGqvnsesl.ggrvvsGvGgqldFvrgaalskggksiialpStakkg 92 
                      G k++yd +++  pk+ lr+++++n+pe+i++   v+ +n+ +evd+++++ns+++ g+r+++G+Gg+ dF+r+a++     si+++pSt++++
       EEA18619.1 332 GFKRFYDGWERyAPKLLLRSQQVSNSPEIIRR-LGVIGMNTPVEVDIYAHANSTCVmGSRMLNGLGGSADFLRNAKY-----SIMHTPSTRPSK 419
                      89********99*******************9.********************************************.....*********987 PP

                      T....EESEESS-STTSSECE-TTT-SEEEETTEEEE-TT--HHHHHHHHHT.TS-HHHHHHHHHH CS
  AcetylCoA_hyd_C  93 e....iSrIvpslkegahvtttrhdvdyvvTEyGiadLrgkslreraealik.iAhpdfreeLlee 153
                      +    +S+Ivp+++   hv++t+hd+d+vvTE+G+ad+rg+s+rera+ +i+ +Ahpd+++ L+++
       EEA18619.1 420 TdptgVSCIVPMCT---HVDQTEHDLDVVVTEQGLADVRGLSPRERARVIIDkCAHPDYKPILQDY 482
                      556669********...*********************************************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (524 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       395  (0.0220313); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.30s 00:00:00.89 Elapsed: 00:00:00.50
# Mc/sec: 3129.29
//
Query:       EEA18620.1  [L=478]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      8e-21   74.4   0.2    1.5e-06   28.7   0.0    5.9  7  Ank_2       Ankyrin repeats (3 copies)
    2.2e-19   67.5   4.2      0.052   14.1   0.0   10.1 10  Ank_3       Ankyrin repeat
    2.2e-17   63.2   2.2      0.011   16.3   0.0    7.8  8  Ank_4       Ankyrin repeats (many copies)
    8.9e-14   51.2   4.0      0.041   14.3   0.0    8.7  8  Ank         Ankyrin repeat
    1.2e-09   38.2   3.2     0.0044   17.3   0.0    6.5  7  Ank_5       Ankyrin repeats (many copies)
     0.0012   18.7   0.8      0.003   17.4   0.8    1.7  1  F-box-like  F-box-like


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   6.1e-06     0.018       3      80 ..      64     144 ..      27     147 .. 0.79
   2 !   16.3   0.0   3.6e-06     0.011      25      76 ..     116     184 ..      87     190 .. 0.69
   3 !   28.7   0.0   5.2e-10   1.5e-06       4      81 ..     168     259 ..     165     261 .. 0.79
   4 !   23.5   0.0   2.2e-08   6.5e-05       4      75 ..     200     292 ..     197     301 .. 0.64
   5 !   12.7   0.0   4.9e-05      0.15       8      82 ..     281     364 ..     274     365 .. 0.63
   6 !    8.0   0.0    0.0015       4.4       4      36 ..     341     379 ..     338     385 .. 0.77
   7 ?    3.9   0.0     0.028        83      11      33 ..     435     461 ..     424     477 .. 0.59

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 6.1e-06
       Ank_2   3 lAakngnlelvklLl.egadpnkngktaLhyAakngnlei.vklLleh....ad....ndgrtpLhyAarsghleivklLlekgadin 80 
                  +   gn+ +v  +l +gadpn     aL+ Aa+    ++ + +L +     +      + +tpL +Aa  g   +v lLl +ga ++
  EEA18620.1  64 RCTITGNTAAVSRFLhHGADPN-----ALISAASIR--QVkANILSSSssgaFGflpwHNMQTPLNIAANMGDDALVSLLLSYGARVD 144
                 5556677767777776888886.....999888877..443677776455552244555678*******889999******9999875 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 3.6e-06
       Ank_2  25 ngktaLhyAakngnleivklLleh..............ad...ndgrtpLhyAarsghleivklLlekg 76 
                 n +t+L +Aa  g+  +v+lLl++              +     + + +   A  sgh  +v+lLl++g
  EEA18620.1 116 NMQTPLNIAANMGDDALVSLLLSYgarvdgfspkghqgTGegrHTVQPAVVDALLSGHKSTVRLLLKRG 184
                 679**********9889*****9776644544444433113323344478999999*********9777 PP

  == domain 3  score: 28.7 bits;  conditional E-value: 5.2e-10
       Ank_2   4 AakngnlelvklLl.egadpn.k..ngktaLhyAakngnleivklLleh....ad...ndgrtpLhyAars...ghleivklLlekgadinl 81 
                 A ++g+ ++v+lLl  g+ ++    +    + +A+ + +l ++klL+++    ++   ++g  pL  A++s   g  eiv++Ll++gadi++
  EEA18620.1 168 ALLSGHKSTVRLLLkRGSPMHdYgmERGGLINCAIAREQLSLLKLLVNEfeadVNftwQEGVYPLNRAVSSsseGAAEIVRFLLDNGADIEA 259
                 45579999******8887777425433345558888888999*****9778554477888*********99888899************986 PP

  == domain 4  score: 23.5 bits;  conditional E-value: 2.2e-08
       Ank_2   4 Aakn.gnlelvklLl..egadpn...kngktaLhyAakn...gnleivklLleh......ad....nd..grtpLhyAarsghleivklLlek 75 
                 +a   ++l+l+klL+  ++ad+n   ++g  +L  A+++   g  eiv++Ll++      a+    n+  g+  L   +r+g +++++lLl +
  EEA18620.1 200 CAIArEQLSLLKLLVneFEADVNftwQEGVYPLNRAVSSsseGAAEIVRFLLDNgadieaANsygeNTghGQRLLNQVIRQGTIDTLRLLLTR 292
                 555336677888888555566667444888888888885333566888888886655555334444224466788888888888888888855 PP

  == domain 5  score: 12.7 bits;  conditional E-value: 4.9e-05
       Ank_2   8 gnlelvklLl.eg...adpn.k....ngktaLhyAakngnleivklLleh....ad.ndgrtpLhyAarsghleivklLlekgadinlk 82 
                 g  ++++lLl  g   a    +    +g + +++  +  + e+v+lLl+h     d  +g+  L++  r  +l+i++l++++g+d+n++
  EEA18620.1 281 GTIDTLRLLLtRGvvtA--TaQalsnKGVFRIWLMQRC-DAEVVRLLLQHgyfePDsINGT--LMAVMRARRLDILQLFMDSGVDPNTR 364
                 55566666666443321..1212222444444444444.4599******999554443344..888888899**************987 PP

  == domain 6  score: 8.0 bits;  conditional E-value: 0.0015
       Ank_2   4 Aakn.gnlelvklLl.egadpn..k..ngktaLhyAakn 36 
                 A++    l++++l++ +g+dpn  +   g+t Lh+A+++
  EEA18620.1 341 AVMRaRRLDILQLFMdSGVDPNtrTgiAGLTLLHTAVIY 379
                 566434568999999999**997636899*****99975 PP

  == domain 7  score: 3.9 bits;  conditional E-value: 0.028
       Ank_2  11 elvklLl.egadpn..k.ngktaLhyA 33 
                 e+v+ L+  gad+n  +  g ++L +A
  EEA18620.1 435 EIVRCLIrGGADVNglDaRGASPLALA 461
                 355555555555555434555555554 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.0      0.12   3.5e+02       7      31 .]      63      86 ..      60      86 .. 0.78
   2 !   12.0   0.0   8.7e-05      0.26       2      30 ..     117     144 ..     116     145 .. 0.91
   3 ?    0.7   0.0      0.39   1.2e+03       9      26 ..     168     184 ..     167     186 .. 0.86
   4 ?    3.1   0.1     0.067     2e+02       6      30 ..     198     222 ..     196     223 .. 0.88
   5 !   14.1   0.0   1.7e-05     0.052       2      30 ..     228     258 ..     227     259 .. 0.90
   6 ?    5.1   0.0     0.015        45       1      26 [.     269     293 ..     269     294 .. 0.91
   7 ?    1.3   0.0      0.26   7.8e+02      13      26 ..     316     328 ..     311     333 .. 0.71
   8 ?    5.2   0.0     0.014        42       6      30 ..     339     362 ..     339     363 .. 0.90
   9 ?    4.2   0.0      0.03        91       2      14 ..     369     381 ..     368     387 .. 0.86
  10 !    7.9   0.0    0.0019       5.7      12      30 ..     431     448 ..     428     449 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.12
       Ank_3  7 hlAarsgnleivkfLlenkgadvna 31
                +++   gn++ v  +l  +gad+na
  EEA18620.1 63 FRCTITGNTAAVSRFLH-HGADPNA 86
                55556678888999999.9****96 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 8.7e-05
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                  +tpL +Aa  g+ ++v +Ll  +ga v+
  EEA18620.1 117 MQTPLNIAANMGDDALVSLLLS-YGARVD 144
                 58********************.999775 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 0.39
       Ank_3   9 AarsgnleivkfLlenkg 26 
                 A++sg+ + v++Ll+ +g
  EEA18620.1 168 ALLSGHKSTVRLLLK-RG 184
                 788999999*****9.66 PP

  == domain 4  score: 3.1 bits;  conditional E-value: 0.067
       Ank_3   6 LhlAarsgnleivkfLlenkgadvn 30 
                 + +A+    l+++k+L++++ advn
  EEA18620.1 198 INCAIAREQLSLLKLLVNEFEADVN 222
                 568999999999************9 PP

  == domain 5  score: 14.1 bits;  conditional E-value: 1.7e-05
       Ank_3   2 GetpLhlAarsgnl...eivkfLlenkgadvn 30 
                 G +pL +A++s +    eiv+fLl+ +gad+ 
  EEA18620.1 228 GVYPLNRAVSSSSEgaaEIVRFLLD-NGADIE 258
                 789***********98779******.8***96 PP

  == domain 6  score: 5.1 bits;  conditional E-value: 0.015
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkg 26 
                 +G+ +L +++r+g ++ +++Ll  +g
  EEA18620.1 269 HGQRLLNQVIRQGTIDTLRLLLT-RG 293
                 6999******************8.76 PP

  == domain 7  score: 1.3 bits;  conditional E-value: 0.26
       Ank_3  13 gnleivkfLlenkg 26 
                 ++ e+v++Ll++ g
  EEA18620.1 316 CDAEVVRLLLQH-G 328
                 34469******5.4 PP

  == domain 8  score: 5.2 bits;  conditional E-value: 0.014
       Ank_3   6 LhlAarsgnleivkfLlenkgadvn 30 
                 L+ ++r+ +l+i++++ +  g+d+n
  EEA18620.1 339 LMAVMRARRLDILQLFMD-SGVDPN 362
                 7889999999********.9****9 PP

  == domain 9  score: 4.2 bits;  conditional E-value: 0.03
       Ank_3   2 GetpLhlAarsgn 14 
                 G t+Lh+A+ ++ 
  EEA18620.1 369 GLTLLHTAVIYCA 381
                 89*******9875 PP

  == domain 10  score: 7.9 bits;  conditional E-value: 0.0019
       Ank_3  12 sgnleivkfLlenkgadvn 30 
                 +++ eiv+ L++  gadvn
  EEA18620.1 431 CAPEEIVRCLIR-GGADVN 448
                 55668*******.9****9 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.0     0.017        52       4      30 ..      61      87 ..      59      98 .. 0.81
   2 !    7.4   0.0    0.0022       6.6       3      55 .]     119     181 ..     118     181 .. 0.70
   3 !    7.0   0.0    0.0031       9.2       8      55 .]     168     214 ..     159     214 .. 0.82
   4 !    7.0   0.0    0.0031       9.3       7      46 ..     200     239 ..     194     245 .. 0.83
   5 !   13.9   0.0     2e-05     0.061      15      55 .]     245     290 ..     234     290 .. 0.83
   6 ?    4.1   0.0     0.024        71       7      30 ..     311     335 ..     310     345 .. 0.75
   7 !   16.3   0.0   3.7e-06     0.011       7      43 ..     340     377 ..     336     381 .. 0.88
   8 ?    0.0   0.0      0.47   1.4e+03      13      39 ..     433     458 ..     428     461 .. 0.82

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.017
       Ank_4  4 aLhyaaisgrlelvrlLlekgadinaq 30
                aL+++ i g++ +v + l +gad+na 
  EEA18620.1 61 ALFRCTITGNTAAVSRFLHHGADPNAL 87
                5777778899999999999*****997 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0022
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrs......Get....alhiAakrgnveilklLl 55 
                 t+L  aa++g+  lv lLl++ga ++  +++       G+     a+  A++ g+++ ++lLl
  EEA18620.1 119 TPLNIAANMGDDALVSLLLSYGARVDGFSPKGhqgtgeGRHtvqpAVVDALLSGHKSTVRLLL 181
                 6777899****************9999888764444332223333666666777777777765 PP

  == domain 3  score: 7.0 bits;  conditional E-value: 0.0031
       Ank_4   8 aaisgrlelvrlLlekgadinaqdnrsGet...alhiAakrgnveilklLl 55 
                 a  sg+  +vrlLl +g   +    ++G+    ++ +A+ r++++ lklL+
  EEA18620.1 168 ALLSGHKSTVRLLLKRGSPMH----DYGMErggLINCAIAREQLSLLKLLV 214
                 6679**********9998843....56886677999999999999999996 PP

  == domain 4  score: 7.0 bits;  conditional E-value: 0.0031
       Ank_4   7 yaaisgrlelvrlLl.ekgadinaqdnrsGetalhiAakrg 46 
                  a++ ++l l++lL+ e+ ad+n +   +G  +l +A++ +
  EEA18620.1 200 CAIAREQLSLLKLLVnEFEADVNFT-WQEGVYPLNRAVSSS 239
                 57889**********5468****99.999********9876 PP

  == domain 5  score: 13.9 bits;  conditional E-value: 2e-05
       Ank_4  15 elvrlLlekgadinaqdnrsGet......alhiAakrgnveilklLl 55 
                 e+vr+Ll++gadi a  n++Ge+      +l  +++ g ++ l+lLl
  EEA18620.1 245 EIVRFLLDNGADIEAA-NSYGENtghgqrLLNQVIRQGTIDTLRLLL 290
                 78*************8.*99664455555***************997 PP

  == domain 6  score: 4.1 bits;  conditional E-value: 0.024
       Ank_4   7 yaaisgrlelvrlLlekg.adinaq 30 
                 ++++ ++ e+vrlLl++g  +++  
  EEA18620.1 311 WLMQRCDAEVVRLLLQHGyFEPDSI 335
                 67788999*********96666654 PP

  == domain 7  score: 16.3 bits;  conditional E-value: 3.7e-06
       Ank_4   7 yaai.sgrlelvrlLlekgadinaqdnrsGetalhiAa 43 
                 +a++ + rl++++l  ++g+d+n ++ + G+t+lh A+
  EEA18620.1 340 MAVMrARRLDILQLFMDSGVDPNTRTGIAGLTLLHTAV 377
                 4455599******************99********998 PP

  == domain 8  score: 0.0 bits;  conditional E-value: 0.47
       Ank_4  13 rlelvrlLlek.gadinaqdnrsGetal 39 
                 ++e+vr L+ + gad+n   +++G ++l
  EEA18620.1 433 PEEIVRCLI-RgGADVNGL-DARGASPL 458
                 567888888.658*****9.99999988 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.7   0.0    0.0036        11      13      30 ..      69      87 ..      60      89 .. 0.80
   2 !    8.5   0.0   0.00096       2.9       3      25 ..     118     141 ..     116     144 .. 0.88
   3 ?    1.1   0.0      0.21   6.2e+02      12      24 ..     171     184 ..     163     189 .. 0.79
   4 ?   -0.9   0.0      0.89   2.6e+03      12      28 ..     204     222 ..     197     224 .. 0.70
   5 !   14.3   0.0   1.4e-05     0.041       2      31 ..     228     261 ..     227     262 .. 0.83
   6 ?    2.9   0.0     0.056   1.7e+02      15      24 ..     318     328 ..     297     336 .. 0.76
   7 ?    2.5   0.0     0.079   2.4e+02      10      31 ..     346     365 ..     339     365 .. 0.71
   8 !    5.6   0.0     0.008        24       2      28 ..     369     448 ..     368     452 .. 0.52

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0036
                TTHHHHHHHH.TTTSTTCB CS
         Ank 13 gkkriiklLL.hGAnlnal 30
                g++  ++ +L hGA++nal
  EEA18620.1 69 GNTAAVSRFLhHGADPNAL 87
                556678889*88*****96 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00096
                 BBHHHHHHHHTTHHHHHHHH.TTT CS
         Ank   3 nTPLHlAatngkkriiklLL.hGA 25 
                  TPL +Aa+ g+   ++lLL +GA
  EEA18620.1 118 QTPLNIAANMGDDALVSLLLsYGA 141
                 7*******9999********7798 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.21
                 HTTHHHHHHHH.TT CS
         Ank  12 ngkkriiklLL.hG 24 
                  g+k+ ++lLL +G
  EEA18620.1 171 SGHKSTVRLLLkRG 184
                 589999****9667 PP

  == domain 4  score: -0.9 bits;  conditional E-value: 0.89
                 HTTHHHHHHHH.T.TTSTT CS
         Ank  12 ngkkriiklLL.h.GAnln 28 
                 + +++ +klL+    A++n
  EEA18620.1 204 REQLSLLKLLVnEfEADVN 222
                 5556789999953359998 PP

  == domain 5  score: 14.3 bits;  conditional E-value: 1.4e-05
                 SBBHHHHHH...HHTTHHHHHHHH.TTTSTTCBT CS
         Ank   2 GnTPLHlAa...tngkkriiklLL.hGAnlnald 31 
                 G +PL +A+   ++g ++i+++LL +GA++ a +
  EEA18620.1 228 GVYPLNRAVsssSEGAAEIVRFLLdNGADIEAAN 261
                 99*****995555555********88****8876 PP

  == domain 6  score: 2.9 bits;  conditional E-value: 0.056
                 HHHHHHHH.TT CS
         Ank  15 kriiklLL.hG 24 
                 +++++lLL hG
  EEA18620.1 318 AEVVRLLLqHG 328
                 78******999 PP

  == domain 7  score: 2.5 bits;  conditional E-value: 0.079
                 HHHTTHHHHHHHH.TTTSTTCBT CS
         Ank  10 atngkkriiklLL.hGAnlnald 31 
                  +   ++i++l+  +G ++n ++
  EEA18620.1 346 RR---LDILQLFMdSGVDPNTRT 365
                 34...45******88****9775 PP

  == domain 8  score: 5.6 bits;  conditional E-value: 0.008
                 SBBHHHHH..............................................HHHTT.........HHHHHHHH.TTTSTT CS
         Ank   2 GnTPLHlA..............................................atngk.........kriiklLL.hGAnln 28 
                 G T LH A                                              +             ++i++ L+  GA++n
  EEA18620.1 369 GLTLLHTAviycavrsmpietglasttvcrdrpmshalnlvrkiesdpsqqistC---IgakvercapEEIVRCLIrGGADVN 448
                 5666776555555555555555555555444444444444444444444443332...022344444489******447**99 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       2.1   6.2e+03      33      44 ..      76      86 ..      67      87 .. 0.64
   2 ?    1.9   0.0     0.099     3e+02      17      36 ..     118     137 ..     114     147 .. 0.77
   3 !   17.3   0.0   1.5e-06    0.0044       7      50 ..     219     266 ..     212     267 .. 0.74
   4 ?    0.6   0.0      0.26   7.9e+02      14      40 ..     268     294 ..     266     296 .. 0.89
   5 ?   -1.4   0.0       1.1   3.3e+03      29      39 ..     318     328 ..     317     342 .. 0.83
   6 !    6.4   0.1    0.0038        11      20      56 .]     339     376 ..     324     376 .. 0.85
   7 !    5.4   0.0    0.0078        23      30      56 .]     435     461 ..     432     461 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 2.1
       Ank_5 33 rlLlargadlnl 44
                r+L+ +gad+n+
  EEA18620.1 76 RFLH-HGADPNA 86
                5555.8888875 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.099
       Ank_5  17 ntpLhvAakygaadvvrlLl 36 
                 +tpL++Aa+ g   +v lLl
  EEA18620.1 118 QTPLNIAANMGDDALVSLLL 137
                 39******988888888888 PP

  == domain 3  score: 17.3 bits;  conditional E-value: 1.5e-06
       Ank_5   7 advnrldgggntpLhvAa...kygaadvvrlLlargadlnltdsrG.l 50 
                 advn + ++g+ pL+ A+   + gaa++vr+Ll++gad+ + +s+G +
  EEA18620.1 219 ADVNFTWQEGVYPLNRAVsssSEGAAEIVRFLLDNGADIEAANSYGeN 266
                 56666666777777766522258**********************955 PP

  == domain 4  score: 0.6 bits;  conditional E-value: 0.26
       Ank_5  14 gggntpLhvAakygaadvvrlLlarga 40 
                 g+g+  L++ +++g  d +rlLl rg+
  EEA18620.1 268 GHGQRLLNQVIRQGTIDTLRLLLTRGV 294
                 78999******************8876 PP

  == domain 5  score: -1.4 bits;  conditional E-value: 1.1
       Ank_5  29 advvrlLlarg 39 
                 a+vvrlLl +g
  EEA18620.1 318 AEVVRLLLQHG 328
                 799****9766 PP

  == domain 6  score: 6.4 bits;  conditional E-value: 0.0038
       Ank_5  20 LhvAakygaadvvrlLlargadlnltdsrG.ltaldlA 56 
                 L+   +++++d+++l+++ g+d+n++++   lt+l+ A
  EEA18620.1 339 LMAVMRARRLDILQLFMDSGVDPNTRTGIAgLTLLHTA 376
                 55555689*******************99999999877 PP

  == domain 7  score: 5.4 bits;  conditional E-value: 0.0078
       Ank_5  30 dvvrlLlargadlnltdsrGltaldlA 56 
                 ++vr L+  gad n  d+rG ++l lA
  EEA18620.1 435 EIVRCLIRGGADVNGLDARGASPLALA 461
                 578888899**************9987 PP

>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.8     1e-06     0.003       2      44 ..       4      44 ..       3      47 .. 0.93

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 1e-06
  F-box-like  2 srLPdEiLlqIFsyLppsdLlrlalVCrrWrrvaldtplLWrr 44
                ++LP+E++l I+  L+ sdL+ l +V ++  +++   p+L++r
  EEA18620.1  4 LDLPTELILLILPSLSESDLTHLLQVHSSLFNIV--LPYLYKR 44
                68**********99***************99999..67***98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (478 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.59u 0.25s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 3217.09
//
Query:       EEA18621.1  [L=1594]
Description: transcription factor (Sin3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.4e-80  269.5   8.6    4.4e-80  269.5   8.6    2.8  3  Sin3a_C         C-terminal domain of Sin3a protein
    6.4e-47  157.5   2.4    1.1e-17   63.8   0.0    3.8  3  PAH             Paired amphipathic helix repeat
    1.2e-38  131.1   0.1    3.9e-38  129.5   0.1    2.0  1  Sin3_corepress  Sin3 family co-repressor
  ------ inclusion threshold ------
      0.012   15.9   1.6      0.012   15.9   1.6    3.4  3  TSP_NTD         Tail specific protease N-terminal domain


Domain annotation for each model (and alignments):
>> Sin3a_C  C-terminal domain of Sin3a protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   3.7         2   8.9e+03     218     258 ..      98     137 ..      85     151 .. 0.47
   2 ?   -2.4   0.0      0.69   3.1e+03      60      87 ..     263     287 ..     251     290 .. 0.79
   3 !  269.5   8.6   9.8e-84   4.4e-80       1     285 [.    1200    1473 ..    1200    1474 .. 0.96

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 2
     Sin3a_C 218 ereklkkvfLkRnlkaerkeeekkeeeeqekaekeeeaeke 258
                 er++ ++ +L+R  ++ + ++e++++e+ e++++e+++e++
  EEA18621.1  98 ERDSREREMLERQRHEDMVHREREQRER-EREHMERQREQQ 137
                 3344444578887765555444433332.233333322222 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.69
     Sin3a_C  60 rleseeeeeeyYsqllelveklldGeid 87 
                 r+   +e+ ++Y+++l+ ++++    id
  EEA18621.1 263 RF---VEQPDVYNRFLDIMKDFKSQAID 287
                 44...78889*********999777776 PP

  == domain 3  score: 269.5 bits;  conditional E-value: 9.8e-84
     Sin3a_C    1 FfaNttfYvflrlfqiLyeRLlkikqaeeqvaeevkerkankvavelgldkkesealalrleseeeeeeyYsqllelveklldGeidqsqfEdslRe 97  
                  ++ N ++Y+f+r f++Ly+RLl++k +e++++e+v+++  +k a+elgl +k +++++ ++   ++++++Y+q+++++e+++++++d s+ E++lR+
  EEA18621.1 1200 LYSNLNVYCFFRSFELLYSRLLRVKLHEKEAHEDVRRQLLPKAAQELGLLEKTPTDFFYDT---SPNANLYQQIVRMCEEVVKNDLDASHLEETLRR 1293
                  699**********************************************************...********************************* PP

     Sin3a_C   98 mfgikaYklfTldKliqalvkqlqtiv.sDek..cqellelfekerskeettsqdeisyrkkaekllkdenlfriewkseskkltiqlldkddetld 191 
                  ++++++Y+l+ l+K+++ +++++ +i+  D k  ++++++lf ker+keett+++ei+yrk++e+++kd++++ri+++++++k ++qll  +d+t++
  EEA18621.1 1294 YYLKSGYQLYNLEKILSGIARFVAAIFnGDVKdrSADIVNLFFKEREKEETTHNQEIQYRKQVERMVKDGDIYRITYNPTTQKTQVQLLTAEDSTFE 1390
                  ***************************9998889*************************************************************** PP

     Sin3a_C  192 ddeveaeerwkeYvesYvlveptegvereklkkvfLkRnlkaerkeeekkeeeeqekaekeeeaekeleveekleiriclnsyklvyvpgtedv 285 
                  ++e+++e+rw++Yv+ Y++++ptegv+ ++++++fLkRnl+a+ +++e+ ++  +           +l ++++l iric+nsy+++y+pg+ d+
  EEA18621.1 1391 NEELSQEARWSYYVSAYTMRDPTEGVSFSQMRMPFLKRNLPAKLEQDEEYNRYYR-----------RLVHHDGLIIRICANSYHILYEPGSYDW 1473
                  ***999**********************************888887777776554...........46778*********************98 PP

>> PAH  Paired amphipathic helix repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.8   0.0   2.5e-21   1.1e-17       1      45 []     269     313 ..     269     313 .. 0.99
   2 !   63.3   2.9   3.8e-21   1.7e-17       1      45 []     524     568 ..     524     568 .. 0.99
   3 !   25.6   0.0   2.2e-09   9.9e-06       3      44 ..     736     777 ..     734     778 .. 0.95

  Alignments for each domain:
  == domain 1  score: 63.8 bits;  conditional E-value: 2.5e-21
         PAH   1 evYkeFLdiLhdyqkeqidskeVyeqVskLFhdhpdLlreFnqFL 45 
                 +vY++FLdi++d++++ id+++V+++Vs+LF +hp L+++Fn+FL
  EEA18621.1 269 DVYNRFLDIMKDFKSQAIDTPGVIQRVSNLFTGHPALIQGFNTFL 313
                 79******************************************8 PP

  == domain 2  score: 63.3 bits;  conditional E-value: 3.8e-21
         PAH   1 evYkeFLdiLhdyqkeqidskeVyeqVskLFhdhpdLlreFnqFL 45 
                 e+Yk+FL+iL++yq+e++ +++Vy+qV +LFh  pdLl++F+qFL
  EEA18621.1 524 EIYKQFLEILQTYQRESKPIQDVYAQVTQLFHTAPDLLEDFKQFL 568
                 89******************************************8 PP

  == domain 3  score: 25.6 bits;  conditional E-value: 2.2e-09
         PAH   3 YkeFLdiLhdyqkeqidskeVyeqVskLFhdhpdLlreFnqF 44 
                 + eFL++++ y+++ id++ ++++ + ++ ++p+L+ +F++F
  EEA18621.1 736 FGEFLKLCNLYSNDLIDRNVLVKRAAGFIGSNPELMSWFKRF 777
                 679*************************************** PP

>> Sin3_corepress  Sin3 family co-repressor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  129.5   0.1   8.7e-42   3.9e-38       2      97 ..     806     900 ..     805     901 .. 0.96

  Alignments for each domain:
  == domain 1  score: 129.5 bits;  conditional E-value: 8.7e-42
  Sin3_corepress   2 rlgpsYrlLpksyqqpkcsgrdelekevLNdewvsvptwasedsgsfkasrknqyeealfrcEderyelDmvieanrstiklleelakkiesmse 96 
                     +lgpsYrlLpk+++q++csgrdel+ +vLNdew+s+ptw+sedsg f+a+rknq+e+al+r+E++r+++D +iea+ +ti+l+e++ +++  mse
      EEA18621.1 806 SLGPSYRLLPKRERQKPCSGRDELCYSVLNDEWASHPTWESEDSG-FVAHRKNQFEDALHRIEEDRHDYDHHIEACVRTIQLIEPIVQQFLVMSE 899
                     689*****************************************8.******************************************9998887 PP

  Sin3_corepress  97 e 97 
                      
      EEA18621.1 900 A 900
                     5 PP

>> TSP_NTD  Tail specific protease N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.9   1.6   2.6e-06     0.012      67     155 ..     917    1015 ..     914    1030 .. 0.79
   2 ?   -1.6   0.1      0.59   2.7e+03      39      80 ..    1183    1224 ..    1179    1246 .. 0.84
   3 ?   -2.9   1.8       1.5   6.9e+03     176     176 ..    1370    1370 ..    1265    1461 .. 0.65

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 2.6e-06
     TSP_NTD   67 eiynlyqkrieerke...yikellkkpfdfskdetleldrekapwakneaelkelwrkrlkneilaelklk.......skkdk...eikkskeelek 150 
                   iy+++ k++ +r+    +i++++++p  +     ++l+++ ++w +++ e++++wr++++  + ++l  +       +   k   + k+  +e+++
  EEA18621.1  917 SIYKRVIKKVYDRQRgelIIQQMFERPCHVLPVLLYRLKQKCEEWKASQREWDKVWREQMQKCFWRSLDHQaitnkgmD---KklfSSKNIHNEIQA 1010
                  7899999999888775557999999****9999*****************************99989988865544322...134455666666666 PP

     TSP_NTD  151 ryeeq 155 
                  +yee 
  EEA18621.1 1011 KYEEG 1015
                  66664 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.59
     TSP_NTD   39 lqsDidefekyreklddalkngdlsfaeeiynlyqkrieerk 80  
                  lq +++  + y++k+   + n ++  ++  ++l+++r+ + k
  EEA18621.1 1183 LQREYNLNQSYEKKVHHLYSNLNVYCFFRSFELLYSRLLRVK 1224
                  566666667999999999999999999999999999998865 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 1.5
     TSP_NTD  176 l 176 
                  +
  EEA18621.1 1370 Y 1370
                  1 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1594 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1422  (0.0793128); expected 358.6 (0.02)
Passed bias filter:                      607  (0.0338558); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.07u 0.34s 00:00:01.41 Elapsed: 00:00:00.52
# Mc/sec: 9229.71
//
Query:       EEA18622.1  [L=470]
Description: protein phosphatase PP2A regulatory B subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      6e-13   49.1   3.0       0.12   13.3   0.3    6.4  7  WD40         WD domain, G-beta repeat
       0.01   16.1   0.2        2.9    8.2   0.0    3.7  5  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.3   0.0    0.0011       9.6      13      36 ..      32      55 ..       8      57 .. 0.77
   2 !    6.9   0.0    0.0014        12      22      38 .]     104     119 ..      70     119 .. 0.79
   3 !   12.5   0.1   2.3e-05      0.21       9      38 .]     184     213 ..     176     213 .. 0.81
   4 ?    0.4   0.0      0.16   1.4e+03      14      36 ..     246     262 ..     231     264 .. 0.68
   5 !   13.3   0.3   1.3e-05      0.12      11      38 .]     295     321 ..     286     321 .. 0.89
   6 ?    1.6   0.0     0.064   5.8e+02      16      37 ..     357     378 ..     329     378 .. 0.87
   7 ?   -3.7   0.0         2   1.8e+04      13      26 ..     444     457 ..     441     461 .. 0.70

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0011
                EEEEEEETTSSEEEEEETTSEEEE CS
        WD40 13 vtslafspdgawlasGsdDgtvri 36
                ++ + f++ g++la+G++ g v +
  EEA18622.1 32 ISTVEFDHTGNYLATGDKGGRVVL 55
                57788***********98777766 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0014
                 SSEEEEEETTSEEEEEE CS
        WD40  22 gawlasGsdDgtvriWd 38 
                 +++l+s   D+t+++W+
  EEA18622.1 104 SHFLLSTN-DKTIKLWK 119
                 45688766.*******6 PP

  == domain 3  score: 12.5 bits;  conditional E-value: 2.3e-05
                 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +H  +++s+++++dg  ++s sdD  + +W+
  EEA18622.1 184 AHaYHINSISVNSDGETFIS-SDDLRINLWN 213
                 78666*************96.66*******8 PP

  == domain 4  score: 0.4 bits;  conditional E-value: 0.16
                 EEEEEETTSSEEE.EEETTSEEEE CS
        WD40  14 tslafspdgawla.sGsdDgtvri 36 
                 ts+      ++++ ++s +gt+++
  EEA18622.1 246 TSC------NFFMyASS-KGTIKM 262
                 444......45434899.****97 PP

  == domain 5  score: 13.3 bits;  conditional E-value: 1.3e-05
                 SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  11 ssvtslafspdgawlasGsdDgtvriWd 38 
                 ss+++++fs+dg++++ + d  tv+iWd
  EEA18622.1 295 SSISDVRFSHDGRYIL-SRDYLTVKIWD 321
                 4699999*********.799*******9 PP

  == domain 6  score: 1.6 bits;  conditional E-value: 0.064
                 EEEETTSSEEEEEETTSEEEEE CS
        WD40  16 lafspdgawlasGsdDgtvriW 37 
                 + fs d + +++Gs++++ +i+
  EEA18622.1 357 VVFSGDAQNVMTGSYNNNFMIY 378
                 45999*********99998886 PP

  == domain 7  score: -3.7 bits;  conditional E-value: 2
                 EEEEEEETTSSEEE CS
        WD40  13 vtslafspdgawla 26 
                 + +++++p  + +a
  EEA18622.1 444 ILHMSWHPFEDSIA 457
                 66788888877665 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.2   0.0   0.00033       2.9      40      90 ..      31      98 ..      22     100 .. 0.82
   2 ?   -0.1   0.1      0.13   1.2e+03      38      68 ..      89     121 ..      80     132 .. 0.71
   3 ?   -1.1   0.0      0.26   2.4e+03      41      72 ..     238     270 ..     202     286 .. 0.71
   4 ?   -2.6   0.0      0.79   7.1e+03      40      55 ..     296     311 ..     291     337 .. 0.66
   5 ?    2.6   0.0     0.019   1.7e+02      38      60 ..     441     463 ..     430     468 .. 0.86

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.00033
  ANAPC4_WD40 40 evrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksek.................avtclgWg 90
                  ++ +++ + g+ La + + g+v l++ +++k   +++ ++e                  ++++++W+
   EEA18622.1 31 IISTVEFDHTGNYLATGDKGGRVVLFERNETKKTCEYKFHTEFqshepefdylksleieeKINKIKWC 98
                 588999*********************99988888877776656677888888888888888888886 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.13
  ANAPC4_WD40  38 dsevrsLaW..kpdgklLavaysdgevrlldae 68 
                  ++++++++W  +++ + +  +++d +++l ++ 
   EEA18622.1  89 EEKINKIKWckRQNASHFLLSTNDKTIKLWKVF 121
                  567888888544555666777778888877765 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 0.26
  ANAPC4_WD40  41 vrsLaWkpdg.klLavaysdgevrlldaesgkv 72 
                  +++ +++p   ++++ a s+g++++ d+ +  +
   EEA18622.1 238 ITASEFHPTScNFFMYASSKGTIKMADMRQRAL 270
                  555555554326788889999999998877665 PP

  == domain 4  score: -2.6 bits;  conditional E-value: 0.79
  ANAPC4_WD40  40 evrsLaWkpdgklLav 55 
                  +++++++++dg+ +  
   EEA18622.1 296 SISDVRFSHDGRYILS 311
                  6778888888887653 PP

  == domain 5  score: 2.6 bits;  conditional E-value: 0.019
  ANAPC4_WD40  38 dsevrsLaWkpdgklLavaysdg 60 
                  ++++ +++W+p +  +a+a  ++
   EEA18622.1 441 NKKILHMSWHPFEDSIAIAATNN 463
                  679999********999999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (470 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       580  (0.0323498); expected 358.6 (0.02)
Passed bias filter:                      391  (0.0218082); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.46
# Mc/sec: 3091.98
//
Query:       EEA18623.1  [L=538]
Description: protein phosphatase PP2A regulatory B subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.3e-12   48.0   3.0       0.14   13.1   0.3    6.5  7  WD40         WD domain, G-beta repeat
     0.0099   16.2   0.2        3.3    8.1   0.0    3.6  5  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.0   0.0    0.0013        11      13      36 ..      32      55 ..       8      57 .. 0.78
   2 !    6.7   0.0    0.0016        15      22      38 .]     104     119 ..      71     119 .. 0.79
   3 !   12.3   0.1   2.7e-05      0.24       9      38 .]     184     213 ..     176     213 .. 0.81
   4 ?    0.1   0.0      0.19   1.7e+03      14      36 ..     246     262 ..     232     264 .. 0.67
   5 !   13.1   0.3   1.5e-05      0.14      11      38 .]     295     321 ..     286     321 .. 0.89
   6 ?    1.4   0.0     0.077   6.9e+02      16      37 ..     357     378 ..     330     378 .. 0.87
   7 ?   -3.7   0.0         2   1.8e+04      13      26 ..     444     457 ..     441     463 .. 0.71

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0013
                EEEEEEETTSSEEEEEETTSEEEE CS
        WD40 13 vtslafspdgawlasGsdDgtvri 36
                ++ + f++ g++la+G++ g v +
  EEA18623.1 32 ISTVEFDHTGNYLATGDKGGRVVL 55
                57788***********98777766 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0016
                 SSEEEEEETTSEEEEEE CS
        WD40  22 gawlasGsdDgtvriWd 38 
                 +++l+s   D+t+++W+
  EEA18623.1 104 SHFLLSTN-DKTIKLWK 119
                 45688766.*******6 PP

  == domain 3  score: 12.3 bits;  conditional E-value: 2.7e-05
                 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +H  +++s+++++dg  ++s sdD  + +W+
  EEA18623.1 184 AHaYHINSISVNSDGETFIS-SDDLRINLWN 213
                 78666*************96.66*******8 PP

  == domain 4  score: 0.1 bits;  conditional E-value: 0.19
                 EEEEEETTSSEEE.EEETTSEEEE CS
        WD40  14 tslafspdgawla.sGsdDgtvri 36 
                 ts+      ++++ ++s +gt+++
  EEA18623.1 246 TSC------NFFMyASS-KGTIKM 262
                 444......44434899.****97 PP

  == domain 5  score: 13.1 bits;  conditional E-value: 1.5e-05
                 SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  11 ssvtslafspdgawlasGsdDgtvriWd 38 
                 ss+++++fs+dg++++ + d  tv+iWd
  EEA18623.1 295 SSISDVRFSHDGRYIL-SRDYLTVKIWD 321
                 4699999*********.799*******9 PP

  == domain 6  score: 1.4 bits;  conditional E-value: 0.077
                 EEEETTSSEEEEEETTSEEEEE CS
        WD40  16 lafspdgawlasGsdDgtvriW 37 
                 + fs d + +++Gs++++ +i+
  EEA18623.1 357 VVFSGDAQNVMTGSYNNNFMIY 378
                 45999*********99998886 PP

  == domain 7  score: -3.7 bits;  conditional E-value: 2
                 EEEEEEETTSSEEE CS
        WD40  13 vtslafspdgawla 26 
                 + +++++p  + +a
  EEA18623.1 444 ILHMSWHPFEDSIA 457
                 66788888887765 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.1   0.0   0.00037       3.3      39      90 ..      30      98 ..      17     100 .. 0.83
   2 ?   -0.5   0.1      0.17   1.6e+03      38      68 ..      89     121 ..      83     132 .. 0.70
   3 ?   -1.4   0.0      0.32   2.9e+03      41      72 ..     238     270 ..     202     285 .. 0.70
   4 ?   -2.9   0.0      0.99   8.8e+03      40      55 ..     296     311 ..     292     337 .. 0.65
   5 ?    3.2   0.0     0.012   1.1e+02      38      63 ..     441     466 ..     430     470 .. 0.85

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00037
  ANAPC4_WD40 39 sevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksek.................avtclgWg 90
                   ++ +++ + g+ La + + g+v l++ +++k   +++ ++e                  ++++++W+
   EEA18623.1 30 DIISTVEFDHTGNYLATGDKGGRVVLFERNETKKTCEYKFHTEFqshepefdylksleieeKINKIKWC 98
                 5688999*********************99988888877776656677888888888888888888886 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.17
  ANAPC4_WD40  38 dsevrsLaW..kpdgklLavaysdgevrlldae 68 
                  ++++++++W  +++ + +  +++d +++l ++ 
   EEA18623.1  89 EEKINKIKWckRQNASHFLLSTNDKTIKLWKVF 121
                  567888888554555667777788888887765 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.32
  ANAPC4_WD40  41 vrsLaWkpdg.klLavaysdgevrlldaesgkv 72 
                  +++ +++p   ++++ a s+g++++ d+ +  +
   EEA18623.1 238 ITASEFHPTScNFFMYASSKGTIKMADMRQRAL 270
                  555555554326788889999999998877655 PP

  == domain 4  score: -2.9 bits;  conditional E-value: 0.99
  ANAPC4_WD40  40 evrsLaWkpdgklLav 55 
                  +++++++++dg+ +  
   EEA18623.1 296 SISDVRFSHDGRYILS 311
                  6778888888887653 PP

  == domain 5  score: 3.2 bits;  conditional E-value: 0.012
  ANAPC4_WD40  38 dsevrsLaWkpdgklLavaysdgevr 63 
                  ++++ +++W+p +  +a+a  ++   
   EEA18623.1 441 NKKILHMSWHPFEDSIAIAATNNVSD 466
                  68999**************9998655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (538 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       721  (0.0402142); expected 358.6 (0.02)
Passed bias filter:                      501  (0.0279436); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.41
# Mc/sec: 3900.34
//
Query:       EEA18624.1  [L=429]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
  ------ inclusion threshold ------
      0.056   13.2   1.5      0.093   12.4   1.5    1.3  1  Cactin_mid  Conserved mid region of cactin


Domain annotation for each model (and alignments):
>> Cactin_mid  Conserved mid region of cactin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   1.5   5.2e-06     0.093     108     186 ..     305     387 ..     302     400 .. 0.70

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 5.2e-06
  Cactin_mid 108 lvvckdeleklkkkeeekeaaeeaeesgi.hasveadikkilkgksleeLeelekqikekLe..sge..avDveYWesllkklk 186
                 +++   ++++ +++++++++++e+++++i ++s   di++il+   +++ e+l++ + + L   + e  +vD++Y e +   lk
  EEA18624.1 305 QMIDMFRRQQPQHQQDQETHEKEDRNKRItANSLVPDIDSILSTAATNKHEALREAVITNLVgaE-EwlHVDQQYNEDVWGYLK 387
                 5555556666444444444445666665526789**************************99643.3479*****999988776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (429 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       799  (0.0445647); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.42
# Mc/sec: 3051.29
//
Query:       EEA18625.1  [L=627]
Description: fumarate reductase Osm1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-83  281.5   0.2    1.5e-83  281.2   0.2    1.1  1  FAD_binding_2  FAD binding domain
    3.7e-22   78.3   0.1    3.2e-20   72.0   0.0    3.2  3  Cyt-b5         Cytochrome b5-like Heme/Steroid binding domain
    1.8e-13   50.8   0.1    3.3e-13   50.0   0.1    1.4  1  DAO            FAD dependent oxidoreductase
    2.7e-09   36.9   1.7    1.2e-08   34.8   1.7    1.9  1  FAD_oxidored   FAD dependent oxidoreductase
    3.9e-08   33.4   1.8      1e-07   32.0   0.2    2.5  3  NAD_binding_8  NAD(P)-binding Rossmann-like domain
      8e-08   31.9   0.2    7.9e-07   28.6   0.2    2.3  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    1.1e-06   28.2   0.1      0.013   14.8   0.0    2.2  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
    2.1e-06   26.7   4.1    8.6e-05   21.4   1.4    3.0  2  HI0933_like    HI0933-like protein
    0.00012   21.4   0.1    0.00021   20.7   0.1    1.3  1  FAD_binding_3  FAD binding domain
    0.00019   20.8   0.6       0.03   13.6   0.1    2.3  2  Thi4           Thi4 family
    0.00051   19.2   2.3       0.18   10.9   0.5    2.3  2  GIDA           Glucose inhibited division protein A
     0.0057   16.0   1.4          2    7.6   0.0    3.0  3  Amino_oxidase  Flavin containing amine oxidoreductase
     0.0074   16.3   2.0       0.18   11.8   2.0    2.6  1  NAD_binding_9  FAD-NAD(P)-binding
  ------ inclusion threshold ------
      0.021   15.4   2.4        5.2    7.7   0.2    2.8  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
      0.054   12.8   0.2       0.11   11.8   0.2    1.5  1  AlaDh_PNT_C    Alanine dehydrogenase/PNT, C-terminal domain


Domain annotation for each model (and alignments):
>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  281.2   0.2   1.3e-86   1.5e-83       2     417 .]       5     445 ..       4     445 .. 0.94

  Alignments for each domain:
  == domain 1  score: 281.2 bits;  conditional E-value: 1.3e-86
                    EEEE--SHHHHHHHHHHHHTTT-EEEEESSSGGGSGGGG--S-EE-TT..SSGGSTC.CHHHHHHHHHHHHTTT-S-HHHHHHHHHTHHHHHHHHH CS
  FAD_binding_2   2 viViGsGlAGLaAAleaaeaGlkvavvekeqefggatawsqGgidavlspeqkkagikdspelhrtdtlkaldeladqplveafveaapeavdeLe 97 
                    viV+G+Gl+GL+AA++   +G +v+v++k + fgg+++ +  gi+ +l+++q ++gi+ds+++  +dtlk++++ a ++l+++++ +++ av++L+
     EEA18625.1   5 VIVVGGGLSGLSAAHTVYLNGGNVLVLDKQSFFGGNSTKATSGINGALTRTQVDLGIQDSVKQFYEDTLKSARDKARPELIKVLTYNSASAVEWLQ 100
                    9*********************************************************************************************** PP

                    HT.T----BCCTSSB-EEE-TT-SSTEEEE-.STT-......HHHHHHHHHHHHHHTCT......EEEEESEEEEEEEECTTEEEEEEEEETTTTC CS
  FAD_binding_2  98 el.gvpfsrtedgpvdvrelGglsatartlhdaadarretlvtghallarlvesarkag......vdfqerteadeLivedgrvtGavvenpesgr 186
                    +   ++++        v++lGg+s + rt++   da++    +g a+ ++l+++++++       v++  ++++++++ e+++vtG++ e   +g+
     EEA18625.1 101 DVfNLDLTL-------VSRLGGHSFP-RTHR-GHDAKF----PGMAITYALMQRLEELTeteperVQVIKKARVTAVNKEGNHVTGVTYE--FNGE 181
                    997888888.......**********.****.777765....999999999999988888889***************************..9999 PP

                    EEEEEES.EEEE-----GG...............GSSSBSSGTT-S-HHHHHHHCTTSSEES..TT-EEEEEEEET....TTTB...B--THHHHT CS
  FAD_binding_2 187 evrirak.avvlatgGfgr.....allkellgaaaeaettnapavtGdglalalragaalnddrmeevqfhPtslvpirdgsgi...Litealrge 273
                    +++  a+  v+latgG+ +     +llk++++     ++tn  ++tGdg+++  + ga+  d  m++vq hPt+l++++d++     L  ealrge
     EEA18625.1 182 THT--ADgVVILATGGYAAdftedSLLKKHRPDTYGLSSTNGTHATGDGQKMLMAIGANGID--MDKVQVHPTGLIDPKDPTSKwkfLAAEALRGE 273
                    886..88799*************************************************888..************99999988999********* PP

                    T-EEE-TTSSBTHGGGS-HHHHHHHHH.HHHHTTTS........CCBEEEE-TT......................SSHHHHHHHSHHHHHHHHHC CS
  FAD_binding_2 274 GgilvdkdGrrFmnelasrdvvsrailekeiaeggs........eanvyldash.....................gldaegleatleaineeaang 340
                    Gg+l+++dG+rF  el +rd vs  ++ ke+++ +         +a+ +ld++                      g+++++l++t++++n +a+ +
     EEA18625.1 274 GGLLLNSDGERFSDELGHRDYVSGQMW-KEKEKNKWpirlilnsKASNVLDFHTrhysgrglmkkmtgkelakeiGCGEAALKKTFDEYNLIAEGK 368
                    ***************************.777666666788888877778888779****************************************9 PP

                    CT......S-TTTSEEE........EEEEEEEES-EEEBETTSBESTTEEESSBTEEE-STCEESSSSTTS--TTHHH CS
  FAD_binding_2 341 ldkdfgrgidpadrpip.gpfyavkvvpaqhytmgGvetdengrvldadgqpipGLYAaGevaaggvhganrlgGnsl 417
                     +++ g+++ ++       +f+ + + p  h+tmgG+e++++++vl+++++p +GLYA+Ge a ggvhganrlgG+sl
     EEA18625.1 369 KKDPWGKKFFHNLPFSIdDTFHVALMEPVLHFTMGGIEINDKAQVLNSEKKPFEGLYACGELA-GGVHGANRLGGSSL 445
                    9988777777666533369999*****************************************.************98 PP

>> Cyt-b5  Cytochrome b5-like Heme/Steroid binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0       1.4   1.7e+03      22      47 ..     102     127 ..      98     135 .. 0.78
   2 ?    1.7   0.0      0.25     3e+02      13      50 ..     309     346 ..     298     363 .. 0.78
   3 !   72.0   0.0   2.7e-23   3.2e-20       1      73 [.     547     618 ..     547     619 .. 0.97

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 1.4
                 EEECTTTC.CCSTTCSHHHHTTTTSBB CS
      Cyt-b5  22 VYDvskfl.skhpGgesailkyaGkDa 47 
                 V++++  l s+  Gg+s+ ++++G+Da
  EEA18625.1 102 VFNLDLTLvSRL-GGHSFPRTHRGHDA 127
                 677775552444.9***********98 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.25
                 EEEEEETTEEEECTTTCCCSTTCSHHHHTTTTSBBHHH CS
      Cyt-b5  13 dlwvairgkVYDvskflskhpGgesailkyaGkDatea 50 
                 ++ ++++ k  +v +f  +h  g+++++k  Gk + ++
  EEA18625.1 309 PIRLILNSKASNVLDFHTRHYSGRGLMKKMTGKELAKE 346
                 666778888888999998888999********987655 PP

  == domain 3  score: 72.0 bits;  conditional E-value: 2.7e-23
                 EHHHHTTTECTTEEEEEETTEEEECTTTCCCSTTCSHHHHTTTTSBBHHHHHHTTGGCHHHHHHHHGGEEEEE CS
      Cyt-b5   1 tleelskhngkndlwvairgkVYDvskflskhpGgesailkyaGkDateafksvvhsekdaekllkkylvGkl 73 
                 t+ee++khn+k+dlw++++g V Dv+++l++hpGg++a+ ++ G+Date+f+   h+++++ k+  + ++G++
  EEA18625.1 547 TMEEVAKHNKKDDLWIVVKGVVMDVTNWLDEHPGGAQALFSHMGRDATEEFEML-HDDEVIPKYASEIVIGRV 618
                 789***************************************************.*********999****98 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.0   0.1   2.7e-16   3.3e-13       1     213 [.       4     209 ..       4     244 .. 0.70

  Alignments for each domain:
  == domain 1  score: 50.0 bits;  conditional E-value: 2.7e-16
                 EEEEECTSHHHHHHHHHHHHTT..EEEEESSSSTTSSGGGSSEEEEESSSSTHHSTHHHHHHHH.HHH.HHHHHHHHHHSSTTSEEEEEEEEEES.SHH CS
         DAO   1 dvviiGGGiiGlstAyeLarrg..VtllekgdiagsgaSgrnsgllhsglrylpeaselarlsl.eal.eelreleeelgididyrrtGllslaa.dee 94 
                 +v+++GGG  Gls+A+     g  V++l+k++++g g S +++  + ++l        +++l   +++ +++++  ++ +   d  r+ l+ + + ++ 
  EEA18625.1   4 RVIVVGGGLSGLSAAHTVYLNGgnVLVLDKQSFFG-GNSTKATSGINGALT-RT----QVDLGIqDSVkQFYEDTLKS-AR--DKARPELIKVLTyNS- 92 
                 59****************99877************.999999999999885.33....23676635542555666665.44..455555555542254. PP

                 HHHHHHHHHHHH.HHTTTTE.EEEEHHHHHHHSTTSTTTSEE.EEETTEEEEEHHHHHHHHHHHHHHT..T-EEEESECEEEEEEEETCEEEEE...EE CS
         DAO  95 elealdkllall.leaglda.elldaeevrelepalpgllga.lfypdtgqvdpakltaalaraaeal..Gveilegtevtgleeedgkvwgve...rt 185
                    a+ ++l+++ + ++l   + l +      +p  + ++g    +p+   + +++l++ l +  e+    v+++++++vt++++e++ v+gv    + 
  EEA18625.1  93 -ASAV-EWLQDVfN-LDLTLvSRLGG----HSFP--RTHRGHdAKFPG--MAITYALMQRLEELTETEpeRVQVIKKARVTAVNKEGNHVTGVTyefN- 179
                 .5666.77777632.33321134444....3566..223331244454..666999999999987666558************9888999***66554. PP

                 CTEEEEEEEE.EEE--GGGHH.HH.HTT.CTT CS
         DAO 186 tpgendaada.vVnaaGawsd.ll.gll.kel 213
                   ge+++ad  v++a+G ++  ++ + l k+ 
  EEA18625.1 180 --GETHTADGvVILATGGYAAdFTeDSLlKKH 209
                 ..766666779********9976654444443 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.8   1.7   9.9e-12   1.2e-08       2     136 ..       5     187 ..       4     197 .. 0.71

  Alignments for each domain:
  == domain 1  score: 34.8 bits;  conditional E-value: 9.9e-12
  FAD_oxidored   2 vvVvGGgpaGvaAAiaAaraGakvlLveergvlGGlltsglvatdignkaee..qvvtgiareflerlrq..rgga..........rlkkrskwn.. 82 
                   v+VvGGg++G+ AA +   +G +vl+++++ + GG++t++  +     +  +    ++  +++f+e   +  r++a          + +++ +w   
    EEA18625.1   5 VIVVGGGLSGLSAAHTVYLNGGNVLVLDKQSFFGGNSTKATSGINGALTRTQvdLGIQDSVKQFYEDTLKsaRDKArpelikvltyNSASAVEWLqd 101
                   9************************************999865554444333565566666666666555443333445665553322244444158 PP

  FAD_oxidored  83 ..............................tfepevakavleeml..aeagvtvllntrlvevekegkriesvtveskegrktirA 136
                                                 +    ++ + lee+   + ++v+v+ ++r+++v+keg+ +++vt e + +++t  +
    EEA18625.1 102 vfnldltlvsrlgghsfprthrghdakfpgMAITYALMQRLEELTetEPERVQVIKKARVTAVNKEGNHVTGVTYEFNGETHTADG 187
                   8999*************999998887655544444444444555586558*****************99******76544544444 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.0   0.2   8.8e-11     1e-07       1      50 [.       7      62 ..       7      76 .. 0.87
   2 ?   -1.5   0.1       2.5     3e+03      29      48 ..     111     130 ..     109     147 .. 0.70
   3 ?   -3.1   0.0       8.1   9.7e+03       8      32 ..     131     163 ..     129     184 .. 0.53

  Alignments for each domain:
  == domain 1  score: 32.0 bits;  conditional E-value: 8.8e-11
                   EE--SHHHHHHHHHHHCCTEEEEEE-SSSSSSGGG-EECE..TT....CEECTS-- CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekrdrlGGraasyev..pg....vrvdygah 50
                   +vG+GlsGl+aA++   +g +vl+l+k++ +GG+++ ++   +g      vd+g +
     EEA18625.1  7 VVGGGLSGLSAAHTVYLNGGNVLVLDKQSFFGGNSTKATSgiNGaltrTQVDLGIQ 62
                   8***********************************99997756666688888876 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 2.5
                    SSSSGGG-EECETTCEECTS CS
  NAD_binding_8  29 drlGGraasyevpgvrvdyg 48 
                    +rlGG++  +++ g+ ++ +
     EEA18625.1 111 SRLGGHSFPRTHRGHDAKFP 130
                    58999999998876544433 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 8.1
                    HHHHHHHHHCC........TEEEEEE-SSSSSS CS
  NAD_binding_8   8 GlvaAylLaka........gfdvlllekrdrlG 32 
                    G+++ y+L ++          +v+++ k++ + 
     EEA18625.1 131 GMAITYALMQRleeltetePERVQVIKKARVTA 163
                    566666665432222222234666666665554 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.6   0.2   6.6e-10   7.9e-07       2     116 ..       4     202 ..       3     237 .. 0.86
   2 ?    0.1   0.0      0.32   3.8e+02     256     280 ..     403     433 ..     396     441 .. 0.68

  Alignments for each domain:
  == domain 1  score: 28.6 bits;  conditional E-value: 6.6e-10
                  SEEEE--SHHHHHHHHHHHHHTS-EEEEETTHCHHHCSHHH.HCHHHHHHHHHHHHH......................................... CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxx......................................... RF
  Pyr_redox_2   2 dvvviGgGpAGlaaaltlaqagakvtlvelegtclnggcll.skallgvaedaeias......................................... 57 
                  +v+v+GgG  Gl+aa+t+  +g++v+++ +++ +++g     ++ + g+  ++++ +                                         
   EEA18625.1   4 RVIVVGGGLSGLSAAHTVYLNGGNVLVL-DKQSFFGGNSTKaTSGINGALTRTQVDLgiqdsvkqfyedtlksardkarpelikvltynsasavewlq 100
                  8***************************.555555544444377888888888888899999************************************ PP

                  ..........................................HHHHCHHHH.CCCCHCCTCEEEEESCEEEEETEEECTCEEEEEESEEEE---EEE- CS
                  ..........................................xxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  58 ..........................................evvkklnqg.ielllgeevvkidpgkkkvklekkkegdeekiaydklvlAtGsspr 112
                                                            e++++ + + +++++++ v+++ ++  +v+  + + + e++ a++ ++lAtG+ + 
   EEA18625.1 101 dvfnldltlvsrlgghsfprthrghdakfpgmaityalmqrlEELTETEPErVQVIKKARVTAVNKEGNHVTGVTYEFNGETHTADGVVILATGGYAA 198
                  ******************************************5556666555******99****99999999966665777788889999*****999 PP

                  BCTC CS
                  xxxx RF
  Pyr_redox_2 113 dlgi 116
                  d++ 
   EEA18625.1 199 DFTE 202
                  9854 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.32
                  TEEE--TTSBE......SSTTEEE-GGGCTE CS
                  xxxxxxxxxxx......xxxxxxxxxxxxxx RF
  Pyr_redox_2 256 ggivvdeflrt......nvpgiyaiGDvagg 280
                  ggi+++++ ++        +g+ya+G  agg
   EEA18625.1 403 GGIEINDKAQVlnsekkPFEGLYACGELAGG 433
                  66666666654444442599*******9943 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.1   0.0   0.00014      0.17     166     211 ..       4      49 ..       2      93 .. 0.72
   2 !   14.8   0.0   1.1e-05     0.013     206     271 ..     130     200 ..     117     218 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00014
  Pyr_redox_3 166 kvvViGgknSavDaAlelvrkgaeVtvvtrgseiekeesdpsyslk 211
                  +v+V+Gg+ S+  aA  ++ +g +V v++++s    ++++    ++
   EEA18625.1   4 RVIVVGGGLSGLSAAHTVYLNGGNVLVLDKQSFFGGNSTKATSGIN 49 
                  6888999999999999999999999888888877777766666665 PP

  == domain 2  score: 14.8 bits;  conditional E-value: 1.1e-05
  Pyr_redox_3 206 psyslkpdienrleelvke..ekikvlfnaevkeikekeeey..kvktedgkkvevkddvvlat.Gykpdl 271
                  p + +     +rleel ++  e+++v+++a+v++++++ +++     + +g++++++  v+lat Gy  d+
   EEA18625.1 130 PGMAITYALMQRLEELTETepERVQVIKKARVTAVNKEGNHVtgVTYEFNGETHTADGVVILATgGYAADF 200
                  5667888899******9999999*************999888423346688999999******84777776 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   1.4   7.2e-08   8.6e-05       2     166 ..       4     197 ..       3     201 .. 0.72
   2 ?    3.5   0.1      0.02        24     355     407 ..     400     456 ..     376     458 .. 0.74

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 7.2e-08
                  SEEEE--SHHHHHHHHHHHHTT--EEEE-SSSSS-...HHHHHCG.GGT-EEEETT-SGGGEEES........STTTTHHH...HHHS-HHHHHHHHH CS
  HI0933_like   2 dviviGgGaAGlmaAisaakrgkrVlllekakklg...rKilisG.gGrcNvTnlseepeellsrype.....npkflksa...lsrftnedlialve 87 
                  +viv+GgG +Gl aA ++  +g +Vl+l+k++ +g    K ++sG +G +  T  +  +++ ++++ e      +++ +       ++++   +++++
   EEA18625.1   4 RVIVVGGGLSGLSAAHTVYLNGGNVLVLDKQSFFGgnsTK-ATSGiNGALTRTQVDLGIQDSVKQFYEdtlksARDKARPElikVLTYNSASAVEWLQ 100
                  69******************************99843234.45564799999997777766666653311111333444432123479********98 PP

                  ...HTT--EEE-STTEEEETT.-CHH.......HHHHHHHHHHH......HT-EEE-S--EEEEECETTE.EEEEE..TTEEEEES.EEEE----SS CS
  HI0933_like  88 ...elgvelkeedsgrlFpvsdkaed.......ivdallkelke......agvklrletevksvekeedgkfrvkt.kseeelead.klvlAtGGlS 166
                     +l+++l  +  g  Fp++++ +d       i  al+++l+e      ++v++  + +v++v+ke +++  v++  ++e+ +ad  ++lAtGG +
   EEA18625.1 101 dvfNLDLTLVSRLGGHSFPRTHRGHDakfpgmaITYALMQRLEEltetepERVQVIKKARVTAVNKEGNHVTGVTYeFNGETHTADgVVILATGGYA 197
                  33358999***********998654333333339999999888733333358******************999999646777777625678***976 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.02
                  EEEEEE-GGGB-TTT-..BBTTSTTEEE-GGGB.SEEE..-TTTHHHHHHHHHHHHHH CS
  HI0933_like 355 vTaGGVdlkevssktm..eskkvpgLffaGEvl.Dveg..vtGGynlqaAwasgyaAG 407
                   T+GG++++  +++ +  e k  +gL+ +GE+   v+g   +GG  l  + + g +AG
   EEA18625.1 400 FTMGGIEIND-KAQVLnsEKKPFEGLYACGELAgGVHGanRLGGSSLLGCVVYGRVAG 456
                  599***9986.4445511556688*******963466633588888888888888887 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.7   0.1   1.7e-07   0.00021       4     150 ..       5     182 ..       3     197 .. 0.76

  Alignments for each domain:
  == domain 1  score: 20.7 bits;  conditional E-value: 1.7e-07
                    EEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSS.S-.-EEEHHHHHHHHHTT-HHHHHHHSEECCCCEEEEEEE.................. CS
  FAD_binding_3   4 VlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlp.ra.dglnqrtmellrqlGledrilaegapnelmgealyne.................. 79 
                    V++VG+G++Gl++a+     G +v++++k+s    ++ +a +g+n    ++  +lG++d++++    +++ + a  +                   
     EEA18625.1   5 VIVVGGGLSGLSAAHTVYLNGGNVLVLDKQSFFGGNStKAtSGINGALTRTQVDLGIQDSVKQFY--EDTLKSARDKArpelikvltynsasavew 98 
                    9******************************9999988663689999999999******998876..55555555555567888999999999999 PP

                    ...........CCCC.....CEEEEEHHCHHCST-CEE--HHHHHHHHHHHHHHHTEEETCSEEEECCEECCCCCCCEEEECCTTEE CS
  FAD_binding_3  80 ...........lsdt.....pkaradlelesspervtvypqteleriLvehaeerglqvrfktevesleqdeegvtaevrdketgee 150
                               +s++     p+ +  +++++ ++++t    ++le + +   e + +qv +k++v+++++++++vt + ++  +ge+
     EEA18625.1  99 lqdvfnldltlVSRLgghsfPRTHRGHDAKFPGMAITYALMQRLEELTET--EPERVQVIKKARVTAVNKEGNHVTGVTYEF-NGET 182
                    88877777776222266677777777777777777777777777664433..455689999999999999999999876644.3444 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.6   0.1   2.5e-05      0.03      20      58 ..       5      42 ..       1      71 [. 0.88
   2 !    5.1   0.0    0.0094        11     202     232 ..     411     441 ..     402     443 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 2.5e-05
                EEEE--SHHHHHHHHHHHHCTTS-EEEEESSSS--TTTT CS
        Thi4 20 vvivGaGssGLtaayylakkpdlkvailersvspGGGaw 58
                v++vG+G sGL+aa+++  + + +v++l+++  +GG + 
  EEA18625.1  5 VIVVGGGLSGLSAAHTVYLN-GGNVLVLDKQSFFGGNST 42
                9******************9.999******999999765 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0094
                 HHHHHHECEEETTEEE-THHHHHHHT-EB-- CS
        Thi4 202 daivkktrevvpnlyvaGmevaevdganRmG 232
                 +++++  ++ +++ly++G  +  v+ganR+G
  EEA18625.1 411 AQVLNSEKKPFEGLYACGELAGGVHGANRLG 441
                 5678888999********************9 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.9   0.5   0.00015      0.18       2      28 ..       5      31 ..       4      53 .. 0.84
   2 !    7.8   0.1    0.0013       1.5     113     153 ..     156     198 ..     136     244 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00015
                EEEE-SSHHHHHHHHHHHHTT--EEEE CS
        GIDA  2 viViGgGhAGceAAlaaarlGakvlLi 28
                viV+GgG++G+ AA ++   G +vl +
  EEA18625.1  5 VIVVGGGLSGLSAAHTVYLNGGNVLVL 31
                9***************99999999877 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0013
                 EEES-EEEEEECTTEEEEEEETTS-EEEEC..EEEE--TT-BT CS
        GIDA 113 iieeeveeliveekkvkgvvtedgetikak..avviatGtflk 153
                 i +++v+ ++ e ++v+gv+ e + + ++   +v++atG + +
  EEA18625.1 156 IKKARVTAVNKEGNHVTGVTYEFNGETHTAdgVVILATGGYAA 198
                 4467899999999*****99886555444448*******9765 PP

>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.6   0.0    0.0017         2       1      31 [.      12      42 ..      12      62 .. 0.86
   2 !    5.2   0.1    0.0088        10     213     262 ..     139     195 ..      62     213 .. 0.72
   3 ?    0.3   0.0      0.28   3.3e+02     331     362 ..     576     606 ..     557     613 .. 0.72

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0017
                   HHHHHHHHHHHHTTEEEEEEESSSSSBTTS- CS
  Amino_oxidase  1 laGLaaArqLlsaGfdVtvlEardrvGGRir 31
                   l+GL+aA++   +G +V+vl  ++ +GG   
     EEA18625.1 12 LSGLSAAHTVYLNGGNVLVLDKQSFFGGNST 42
                   79**************************865 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0088
                    HHHHHH....TTTTEEEETSEEEEEEEE.ETTCEEEEET.TSTEEEESE.EEE-S-H CS
  Amino_oxidase 213 pealae....elrgldirlntrVkeikr.egdgvtvtle.dgevveaDa.VvvTvpl 262
                     ++l+e    e  ++++   +rV+ +++ +++  +vt+e +ge+ +aD  V++++  
     EEA18625.1 139 MQRLEEltetEPERVQVIKKARVTAVNKeGNHVTGVTYEfNGETHTADGvVILATGG 195
                    4444444447889999999*********54445778888899999****44555544 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.28
                    CCSTTTEEEEEEEEECHHHHHHHTTS-HHHHH CS
  Amino_oxidase 331 srappgkglvllvyvggdaaneleslsdeelv 362
                    +  p g +  l++++g da +e+e l d+e++
     EEA18625.1 576 DEHPGGAQA-LFSHMGRDATEEFEMLHDDEVI 606
                    344444444.8888888888888888888776 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   2.0   0.00015      0.18       2     154 ..       7     194 ..       6     196 .. 0.63

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00015
  NAD_binding_9   2 ivGaGprGlavlerLlarakkkspleitlfdpsep.gagrvwrtd.qseelllNvpasemslftddp............................p 67 
                    +vG+G +Gl+++  +  +       ++ + d++++ g g   +++   +  l+ +++    l  +d+                             
     EEA18625.1   7 VVGGGLSGLSAAHTVYLN-----GGNVLVLDKQSFfG-GNSTKATsGINGALTRTQV---DLGIQDSvkqfyedtlksardkarpelikvltynsA 93 
                    678888888877777666.....47788888877645.4333333034444444443...222333344455555777888888777777777778 PP

  NAD_binding_9  68 tfaeWlrerga...........lee...aeeldpddfvpRalyGrYlrdlfeellarlpegvtvevh.raevvdleeradgq.avll.adgaslaa 146
                    + +eWl++  +           + +   +++ ++ +f+  a+  + l +++eel+++ pe  +v+v+ +a+v++++++++++  v+   +g++++a
     EEA18625.1  94 SAVEWLQDVFNldltlvsrlggH-SfprTHRGHDAKFPGMAITYA-LMQRLEELTETEPE--RVQVIkKARVTAVNKEGNHVtGVTYeFNGETHTA 185
                    88888888877776666554431.144455556666666555444.66789999999998..57777477**********9843554369999999 PP

  NAD_binding_9 147 daV.vLAlG 154
                    d V +LA+G
     EEA18625.1 186 DGVvILATG 194
                    976379999 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.2    0.0044       5.2       1      18 [.       4      21 ..       4      47 .. 0.80
   2 ?    6.5   0.1      0.01        12      53      79 ..     149     177 ..     132     183 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0044
                EEEEECSSHHHHHHHHHH CS
   Pyr_redox  1 kvvvvGgGyiglElAgal 18
                +v+vvGgG++gl +A + 
  EEA18625.1  4 RVIVVGGGLSGLSAAHTV 21
                79************9876 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.01
                 T..TEEEECSEEEEEEEEETTSEEEEEEE CS
   Pyr_redox  53 n..gievllntkveeiegsedgvesvklk 79 
                 +   ++v+ +++v++++++++ v++v+ +
  EEA18625.1 149 EpeRVQVIKKARVTAVNKEGNHVTGVTYE 177
                 2559****************99****976 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.2   8.8e-05      0.11      30      60 ..       4      34 ..       1      46 [. 0.93

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 8.8e-05
                 EEEEESTSHHHHHHHHHHHHTT-EEEEEESS CS
  AlaDh_PNT_C 30 kvlviGgGvaGlqAiatakglgakVtvlDvr 60
                 +v+v+GgG  Gl+A++t    g +V vlD++
   EEA18625.1  4 RVIVVGGGLSGLSAAHTVYLNGGNVLVLDKQ 34
                 8***************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (627 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       628  (0.0350271); expected 358.6 (0.02)
Passed bias filter:                      528  (0.0294495); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.73u 0.27s 00:00:01.00 Elapsed: 00:00:00.44
# Mc/sec: 4307.79
//
Query:       EEA18626.1  [L=421]
Description: COP9 signalosome subunit CsnD [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.7e-12   46.1   0.0    1.4e-11   44.8   0.0    1.7  1  PCI       PCI domain
    1.7e-05   24.6   0.1    3.9e-05   23.4   0.1    1.6  1  RPN7      26S proteasome subunit RPN7
  ------ inclusion threshold ------
      0.087   13.1   0.6       0.77   10.1   0.0    2.8  3  TPR_8     Tetratricopeptide repeat
        0.2   11.2   0.1       0.36   10.3   0.1    1.3  1  FAM47     FAM47 family
        0.6   10.7   5.7        7.2    7.2   0.2    3.7  3  TPR_19    Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> PCI  PCI domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.8   0.0     4e-15   1.4e-11       5     104 ..     269     370 ..     265     371 .. 0.95

  Alignments for each domain:
  == domain 1  score: 44.8 bits;  conditional E-value: 4e-15
                 HHHHHHHHTSHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHCESEEEHHHHHHHHTSSH.......HHHHHHHHHHHHTTSSSEEEET CS
         PCI   5 dllkalrsgnlsgfseelkdleeelladdglaqllesLekkvrerllrqvskiyssislerlaklldlsv.......devEkilvklIrdgeirakidq 96 
                 +l + l+  ++++fs+ l+ +     +  ++a+  + L + v+e++l   s+ y++i+ + l   l l++       +++E + ++++++g+++++idq
  EEA18626.1 269 HLDRLLTPEEVAAFSSKLQPH-----QLAKTADGSTVLDRAVIEHNLVAASRLYENIKTDALGAILALKDsgdetagEKAEAYAARMVEQGRLKGSIDQ 362
                 67888999999**********.....77899******************************************************************** PP

                 TTTEEEEC CS
         PCI  97 esgivvfk 104
                  +gi++f 
  EEA18626.1 363 IDGIIYFD 370
                 ******96 PP

>> RPN7  26S proteasome subunit RPN7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.4   0.1   1.1e-08   3.9e-05      64     140 ..     137     213 ..      89     238 .. 0.79

  Alignments for each domain:
  == domain 1  score: 23.4 bits;  conditional E-value: 1.1e-08
                 CC--SHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHCSSS---.HHHHHHHHHHHHHHHHHTT-HHHHHHHHCTS- CS
        RPN7  64 eyctslkhkidmllnlirvaiffndwdlvskylekakellekggdwerknrlkvyeGlallairkfkeAaellldil 140
                 + +++  +k  m+++++r+ ++  d   ++++l+k+k+l +k +d e k  ++ +++ +l+a r+f +A+++  ++ 
  EEA18626.1 137 QRLITDAAKTRMWIRILRLYLEEDDTTNAESFLNKIKNLPSKIEDPELKLHFQLSQARILDARRRFLDASQEYFNVS 213
                 4556778999************************************************************9877665 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       3.4   1.2e+04       6      14 ..      21      29 ..      18      29 .. 0.76
   2 ?   -1.0   0.1      0.82   2.9e+03       7      20 ..     111     124 ..     108     125 .. 0.87
   3 ?   10.1   0.0   0.00022      0.77       2      27 ..     147     172 ..     146     178 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 3.4
                HHHHHHHHT CS
       TPR_8  6 nlgsiylkl 14
                 ++++y++l
  EEA18626.1 21 AKAQLYHDL 29
                689999886 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.82
                 HHHHHHHTT-HHHH CS
       TPR_8   7 lgsiylklgdyeeA 20 
                 l+++y++ ++y +A
  EEA18626.1 111 LADAYESEEEYSAA 124
                 8999*999999887 PP

  == domain 3  score: 10.1 bits;  conditional E-value: 0.00022
                 CHHHHHHHHHHHTT-HHHHHHHHHHH CS
       TPR_8   2 eayynlgsiylklgdyeeAkeyyeka 27 
                 +++ ++ ++yl+  d  +A+++++k 
  EEA18626.1 147 RMWIRILRLYLEEDDTTNAESFLNKI 172
                 79*********************995 PP

>> FAM47  FAM47 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.1    0.0001      0.36      95     150 ..     279     334 ..     271     353 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.0001
       FAM47  95 eaalfsklsparlarkvsleevedqltaecslamspnlgedmppdllrqvlkpldp 150
                  aa+ skl p +la+ +    v d+ + e+ l     l e++  d l  +l  +d 
  EEA18626.1 279 VAAFSSKLQPHQLAKTADGSTVLDRAVIEHNLVAASRLYENIKTDALGAILALKDS 334
                 578889*****************************************999988875 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.4      0.29     1e+03      38      68 .]       3      33 ..       1      33 [. 0.77
   2 ?    7.2   0.2     0.002       7.2      10      53 ..      89     133 ..      86     143 .. 0.84
   3 ?    3.1   0.0     0.037   1.3e+02      25      53 ..     146     174 ..     136     186 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.29
      TPR_19 38 lgqldeAealLdalpeedpddaryasLlAkl 68
                +  ++ A a ++    ++++ + y++Ll k+
  EEA18626.1  3 SQKVASALAEIESSTSQAAKAQLYHDLLSKI 33
                5667788888888888888888899998876 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.002
      TPR_19  10 Alalleq.alqedpknaearllLAeallalgqldeAealLdalpe 53 
                 A+ ll++   + + +++++r  LA+a+ +  ++ +A  +L+ + +
  EEA18626.1  89 AVTLLQSrSASVEEQDSNIREILADAYESEEEYSAAAGVLQGIHL 133
                 556666655678999*************************99876 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.037
      TPR_19  25 aearllLAeallalgqldeAealLdalpe 53 
                  + +++  +++l+  +++ Ae  L+++ +
  EEA18626.1 146 TRMWIRILRLYLEEDDTTNAESFLNKIKN 174
                 5566677899999********99999975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (421 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       774  (0.0431703); expected 358.6 (0.02)
Passed bias filter:                      573  (0.0319594); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.46
# Mc/sec: 2769.51
//
Query:       EEA18627.1  [L=364]
Description: transcription initiation factor iif, beta subunit [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-32  113.2   0.4    2.8e-32  112.2   0.4    1.5  1  TFIIF_beta_N  TFIIF, beta subunit N-terminus
    1.5e-25   89.1   0.3    3.1e-25   88.1   0.3    1.5  1  TFIIF_beta    TFIIF, beta subunit HTH domain
     0.0061   17.4   1.7      0.032   15.0   1.7    2.0  1  Tau95         RNA polymerase III transcription factor (TF)III


Domain annotation for each model (and alignments):
>> TFIIF_beta_N  TFIIF, beta subunit N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.2   0.4   4.6e-36   2.8e-32       2     135 .]      48     195 ..      47     195 .. 0.86

  Alignments for each domain:
  == domain 1  score: 112.2 bits;  conditional E-value: 4.6e-36
  TFIIF_beta_N   2 rkvWLvKvPkfLaekWekeeddeegielGklrikkdtskenkkqrvklklnedlsesekiPkeYelev.......tnervqntyVFsEkdlkgakaa 91 
                   ++vWL+++P  L+++W++ +dd e+i++G++r++ +       +r++l+ln d+++s++iPk+Y l+         + +vqn y+FsEkdl+g+k++
    EEA18627.1  48 QNVWLTRIPTDLWKHWSQLDDD-EEIQIGTVRVEGE---AHDIKRISLRLN-DSPNSKDIPKDYILQRqnvdpksGSFAVQNSYIFSEKDLPGHKNK 139
                   79***************88888.9**********99...45679*******.77*************999999999999****************88 PP

  TFIIF_beta_N  92 saessa.reeaak...........eeakk.......apekrktipkktaLvGrvvheaevrPv 135
                    +e    +    +           +   k       +p+ rktipk+taLvG+v+ e+++ Pv
    EEA18627.1 140 VDEMFGeT----RsmlyesmkreaR---KkatkrkwEPYVRKTIPKQTALVGKVADEFNCMPV 195
                   77766622....2245566665440...15666788**************************7 PP

>> TFIIF_beta  TFIIF, beta subunit HTH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.1   0.3   5.2e-29   3.1e-25       2      65 .]     260     323 ..     259     323 .. 0.98

  Alignments for each domain:
  == domain 1  score: 88.1 bits;  conditional E-value: 5.2e-29
  TFIIF_beta   2 RmprqelldalfelFeeyqYWslkdLkaetrqPeayLkevLeeIAvlhrsGpfknkweLkpeyk 65 
                 R +r+ lld++f lF+ey++W++ d+ka+t+qPe+yLke+Le +A+l+r+G+f+++weLkpe +
  EEA18627.1 260 RRERNVLLDEIFGLFREYSHWKFADIKARTNQPEQYLKETLEMVAHLVRTGDFAMTWELKPEAR 323
                 99***********************************************************986 PP

>> Tau95  RNA polymerase III transcription factor (TF)IIIC subunit HTH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   1.7   5.3e-06     0.032      46     118 ..     235     316 ..     122     317 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 5.3e-06
                 -............--S--TT-----...HHHHHHHHHHHHHHHH-SEEEHHHHHTTS-GGGTTTHHHHGGGTEEEE-SSTTTTEE CS
       Tau95  46 k............PtepeeelvkelkekkelqkaveelkklfeerPiwtrraLknklekkerkklklalpyvaYyfksGPWrdlw 118
                              P +p+++  k+    +e +  ++e+  lf+e   w   ++k ++++ e+  lk+ l +va  +++G + ++w
  EEA18627.1 235 AagtvggfvqqakPLKPRTQENKATR--RERNVLLDEIFGLFREYSHWKFADIKARTNQPEQ-YLKETLEMVAHLVRTGDFAMTW 316
                 25566677667777777776666554..88999999**********************9999.******************9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (364 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       543  (0.0302861); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.41
# Mc/sec: 2682.16
//
Query:       EEA18628.1  [L=442]
Description: CCCH zinc finger protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.6e-12   45.9  27.6    5.7e-06   26.1   1.4    5.4  5  zf-CCCH      Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    3.1e-08   33.4  30.5     0.0051   16.8   1.5    5.9  5  zf_CCCH_4    Zinc finger domain
    4.8e-05   23.5   1.1    4.8e-05   23.5   1.1    3.5  3  zf-CCCH_3    Zinc-finger containing family
     0.0006   19.6   0.1     0.0006   19.6   0.1    5.1  5  zf-CCCH_4    CCCH-type zinc finger
  ------ inclusion threshold ------
      0.024   15.3  24.6      0.031   15.0   0.4    5.0  5  Torus        Torus domain
      0.041   14.4  31.8      0.083   13.4   1.9    4.8  5  zf-CCCH_2    RNA-binding, Nab2-type zinc finger
       0.29   10.9  12.4       0.39   10.5   0.0    4.6  5  zf-C3H1      Putative zinc-finger domain


Domain annotation for each model (and alignments):
>> zf-CCCH  Zinc finger C-x8-C-x5-C-x3-H type (and similar)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.1   1.4   2.2e-09   5.7e-06       2      26 ..     234     258 ..     233     259 .. 0.93
   2 !   20.6   0.1   1.2e-07   0.00031       2      21 ..     261     280 ..     260     284 .. 0.95
   3 !    5.8   1.6    0.0053        14       4      26 ..     292     312 ..     290     313 .. 0.90
   4 ?    4.5   0.3     0.013        33       3      15 ..     318     330 ..     316     337 .. 0.85
   5 !    5.4   0.9    0.0068        17       5      17 ..     343     355 ..     343     359 .. 0.86

  Alignments for each domain:
  == domain 1  score: 26.1 bits;  conditional E-value: 2.2e-09
                 HCHCBCHHHHHS--TTGGG-SSBSC CS
     zf-CCCH   2 ktelCrffmrtGyCkyGdrCkFaHg 26 
                 k elC++f+rtG+C  G+ C+++H+
  EEA18628.1 234 KNELCKRFSRTGSCYKGPDCPYIHD 258
                 669*********************6 PP

  == domain 2  score: 20.6 bits;  conditional E-value: 1.2e-07
                 HCHCBCHHHHHS--TTGGG- CS
     zf-CCCH   2 ktelCrffmrtGyCkyGdrC 21 
                 k+++C++f++tG C+ Gd+C
  EEA18628.1 261 KVAICKDFLQTGKCRSGDSC 280
                 889***************** PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.0053
                 HCBCHHHHHS--TTGGG-SSBSC CS
     zf-CCCH   4 elCrffmrtGyCkyGdrCkFaHg 26 
                 + C +f+r G C+  + C++ H+
  EEA18628.1 292 PVCVHFLR-GRCSN-PECRYTHV 312
                 6899****.*****.*****997 PP

  == domain 4  score: 4.5 bits;  conditional E-value: 0.013
                 CHCBCHHHHHS-- CS
     zf-CCCH   3 telCrffmrtGyC 15 
                  + Cr+f+  GyC
  EEA18628.1 318 APVCRDFAVLGYC 330
                 589********** PP

  == domain 5  score: 5.4 bits;  conditional E-value: 0.0068
                 CBCHHHHHS--TT CS
     zf-CCCH   5 lCrffmrtGyCky 17 
                 +C++++ tG Ck 
  EEA18628.1 343 ECPDYANTGVCKK 355
                 6**********95 PP

>> zf_CCCH_4  Zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   2.3   5.3e-06     0.014       1      19 []     238     257 ..     238     257 .. 0.99
   2 !   16.8   1.5     2e-06    0.0051       1      15 [.     265     280 ..     265     281 .. 0.99
   3 !    7.9   0.8    0.0013       3.4       1      11 [.     294     304 ..     294     311 .. 0.81
   4 !    5.6   0.5    0.0069        18       1      15 [.     321     336 ..     321     337 .. 0.91
   5 ?    4.8   0.2     0.012        32       1      11 [.     344     355 ..     344     356 .. 0.95

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 5.3e-06
   zf_CCCH_4   1 Ckfflq.GtCkkGdkCrFaH 19 
                 Ck f + G+C kG  C+++H
  EEA18628.1 238 CKRFSRtGSCYKGPDCPYIH 257
                 ******************** PP

  == domain 2  score: 16.8 bits;  conditional E-value: 2e-06
   zf_CCCH_4   1 Ckfflq.GtCkkGdkC 15 
                 Ck flq G+C+ Gd+C
  EEA18628.1 265 CKDFLQtGKCRSGDSC 280
                 **************** PP

  == domain 3  score: 7.9 bits;  conditional E-value: 0.0013
   zf_CCCH_4   1 CkfflqGtCkk 11 
                 C +fl+G+C++
  EEA18628.1 294 CVHFLRGRCSN 304
                 *********85 PP

  == domain 4  score: 5.6 bits;  conditional E-value: 0.0069
   zf_CCCH_4   1 Ckfflq.GtCkkGdkC 15 
                 C+ f+  G+C k   C
  EEA18628.1 321 CRDFAVlGYCEKAGEC 336
                 **********998888 PP

  == domain 5  score: 4.8 bits;  conditional E-value: 0.012
   zf_CCCH_4   1 Ckfflq.GtCkk 11 
                 C  +++ G Ckk
  EEA18628.1 344 CPDYANtGVCKK 355
                 9*********98 PP

>> zf-CCCH_3  Zinc-finger containing family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.8     0.041   1.1e+02       4      28 ..     234     259 ..     231     268 .. 0.70
   2 !   23.5   1.1   1.9e-08   4.8e-05      12      58 ..     270     315 ..     259     321 .. 0.88
   3 ?    0.2   1.8      0.32   8.2e+02      16      56 ..     330     364 ..     321     383 .. 0.70

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.041
   zf-CCCH_3   4 kgddcyff.yystctkGdscpfrhee 28 
                 k++ c  f     c kG  cp+ h  
  EEA18628.1 234 KNELCKRFsRTGSCYKGPDCPYIHDA 259
                 5555654413468*********9975 PP

  == domain 2  score: 23.5 bits;  conditional E-value: 1.9e-08
   zf-CCCH_3  12 yystctkGdscpfrheeaalGsetvctlWqegrclrevckfrhmeid 58 
                    +c  Gdsc   he++      vc  + +grc +  c++ h++++
  EEA18628.1 270 QTGKCRSGDSCDLSHEPSPH-RSPVCVHFLRGRCSNPECRYTHVRVT 315
                 4569**************98.6689******************9875 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.32
   zf-CCCH_3  16 ctkGdscpfrheeaalGsetvctlWqegrclrevckfrhme 56 
                 c+k  +c+ rh            + + g c +++c + h++
  EEA18628.1 330 CEKAGECTDRHVYEC------PDYANTGVCKKKKCTLPHVD 364
                 777778888876432......23455677888888877765 PP

>> zf-CCCH_4  CCCH-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.8   1.8    0.0011       2.9       2      22 .]     237     258 ..     236     258 .. 0.93
   2 !   19.6   0.1   2.3e-07    0.0006       2      22 .]     264     285 ..     263     285 .. 0.94
   3 ?    2.0   3.7     0.073   1.9e+02       1      21 [.     292     311 ..     292     312 .. 0.80
   4 ?    0.0   0.4      0.31   7.8e+02       1       8 [.     319     333 ..     319     337 .. 0.67
   5 ?   -2.1   0.2       1.5   3.7e+03       3      12 ..     344     354 ..     344     354 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0011
   zf-CCCH_4   2 lCpyfa.kGsCrfGdnCrFsHd 22 
                 lC+ f  +GsC+ G+ C + Hd
  EEA18628.1 237 LCKRFSrTGSCYKGPDCPYIHD 258
                 7999998**************9 PP

  == domain 2  score: 19.6 bits;  conditional E-value: 2.3e-07
   zf-CCCH_4   2 lCpyfa.kGsCrfGdnCrFsHd 22 
                 +C+ f+ +G+Cr Gd C  sH+
  EEA18628.1 264 ICKDFLqTGKCRSGDSCDLSHE 285
                 7*****999************6 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.073
   zf-CCCH_4   1 rlCpyfakGsCrfGdnCrFsH 21 
                 ++C +f++G+C   + Cr+ H
  EEA18628.1 292 PVCVHFLRGRCSN-PECRYTH 311
                 6899*******87.5677766 PP

  == domain 4  score: 0.0 bits;  conditional E-value: 0.31
   zf-CCCH_4   1 rlCpyfa.......k 8  
                 ++C+ fa       +
  EEA18628.1 319 PVCRDFAvlgycekA 333
                 69****985555545 PP

  == domain 5  score: -2.1 bits;  conditional E-value: 1.5
   zf-CCCH_4   3 Cpyfa.kGsCr 12 
                 Cp +a +G C+
  EEA18628.1 344 CPDYAnTGVCK 354
                 99999888885 PP

>> Torus  Torus domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.1      0.91   2.3e+03      39      79 ..     103     143 ..      71     147 .. 0.59
   2 ?   15.0   0.4   1.2e-05     0.031      67      92 ..     232     258 ..     218     263 .. 0.84
   3 ?    5.1   0.2     0.014        36      70      92 ..     262     285 ..     258     290 .. 0.77
   4 ?   10.7   0.5   0.00025      0.64      69      91 ..     290     311 ..     285     318 .. 0.86
   5 ?   -0.9   2.2         1   2.6e+03      70      91 ..     318     340 ..     313     359 .. 0.78

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.91
                 THHHHS-----S----HHHH----HHHHSTT--B-HHHHHT CS
       Torus  39 kekkkkskekaktrcnikkdsGytkadkekesyfClfFarG 79 
                 +++ ++++ +a+t+   ++++   + + ++e+   + +a+G
  EEA18628.1 103 NSSIYDKEVQARTKAIAETEKSKREKRAKAEEAKVMRYAQG 143
                 44445555566666666666555555555555666666666 PP

  == domain 2  score: 15.0 bits;  conditional E-value: 1.2e-05
                 STT--B-HHHHH.T--SSGGG-SSB-S CS
       Torus  67 ekesyfClfFar.GlCakGkkCeylHr 92 
                 +k++ +C  F+r G C+kG +C y+H+
  EEA18628.1 232 KKKNELCKRFSRtGSCYKGPDCPYIHD 258
                 456789*****989************7 PP

  == domain 3  score: 5.1 bits;  conditional E-value: 0.014
                 --B-HHH.HHT--SSGGG-SSB-S CS
       Torus  70 syfClfF.arGlCakGkkCeylHr 92 
                   +C  F   G C +G +C+  H+
  EEA18628.1 262 VAICKDFlQTGKCRSGDSCDLSHE 285
                 4677755267***********996 PP

  == domain 4  score: 10.7 bits;  conditional E-value: 0.00025
                 T--B-HHHHHT--SSGGG-SSB- CS
       Torus  69 esyfClfFarGlCakGkkCeylH 91 
                 +s +C++F rG C++  +C+y+H
  EEA18628.1 290 RSPVCVHFLRGRCSN-PECRYTH 311
                 5789*********97.78****9 PP

  == domain 5  score: -0.9 bits;  conditional E-value: 1
                 --B-HHHH.HT--SSGGG-SSB- CS
       Torus  70 syfClfFa.rGlCakGkkCeylH 91 
                 + +C  Fa  G+C k  +C+  H
  EEA18628.1 318 APVCRDFAvLGYCEKAGECTDRH 340
                 56899998459****99999777 PP

>> zf-CCCH_2  RNA-binding, Nab2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   1.9   3.2e-05     0.083       2      17 ..     238     257 ..     237     257 .. 0.96
   2 ?    6.3   0.7    0.0057        15       1      13 [.     264     280 ..     264     280 .. 0.97
   3 ?   11.0   2.7   0.00019      0.48       2      17 ..     294     311 ..     294     311 .. 0.96
   4 ?   -2.7   0.0       3.8   9.6e+03       2       6 ..     321     325 ..     321     326 .. 0.88
   5 ?    1.9   2.3      0.14   3.5e+02       2      14 ..     344     359 ..     343     359 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 3.2e-05
   zf-CCCH_2   2 Crffpn...C.tnpkCpFaH 17 
                 C+ f     C ++p+Cp++H
  EEA18628.1 238 CKRFSRtgsCyKGPDCPYIH 257
                 999***************** PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0057
   zf-CCCH_2   1 pCrffpn...C.tnpkC 13 
                 +C++f     C  +++C
  EEA18628.1 264 ICKDFLQtgkCrSGDSC 280
                 7**************** PP

  == domain 3  score: 11.0 bits;  conditional E-value: 0.00019
   zf-CCCH_2   2 Crffpn..CtnpkCpFaH 17 
                 C +f    C np+C++ H
  EEA18628.1 294 CVHFLRgrCSNPECRYTH 311
                 999*************99 PP

  == domain 4  score: -2.7 bits;  conditional E-value: 3.8
   zf-CCCH_2   2 Crffp 6  
                 Cr+f+
  EEA18628.1 321 CRDFA 325
                 ***95 PP

  == domain 5  score: 1.9 bits;  conditional E-value: 0.14
   zf-CCCH_2   2 Crffpn...CtnpkCp 14 
                 C +++n   C+++kC+
  EEA18628.1 344 CPDYANtgvCKKKKCT 359
                 667889999******6 PP

>> zf-C3H1  Putative zinc-finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.0      0.13   3.3e+02       8      20 ..     245     257 ..     242     257 .. 0.85
   2 ?   -2.6   0.3       1.9   4.9e+03       8      20 ..     272     284 ..     271     284 .. 0.66
   3 ?   10.5   0.0   0.00015      0.39       6      22 .]     298     313 ..     298     313 .. 0.90
   4 ?   -2.8   0.1       2.2   5.7e+03       7      14 ..     333     339 ..     331     340 .. 0.71
   5 ?    4.7   0.4      0.01        26       7      17 ..     350     359 ..     344     363 .. 0.80

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.13
     zf-C3H1   8 GGvCnD.psCefQH 20 
                 G  C + p+C++ H
  EEA18628.1 245 G-SCYKgPDCPYIH 257
                 5.99999***9977 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.9
     zf-C3H1   8 GGvCnD.psCefQH 20 
                 G +C   +sC   H
  EEA18628.1 272 G-KCRSgDSCDLSH 284
                 4.777667887666 PP

  == domain 3  score: 10.5 bits;  conditional E-value: 0.00015
     zf-C3H1   6 laGGvCnDpsCefQHFr 22 
                 l+G  C +p+C++ H+r
  EEA18628.1 298 LRG-RCSNPECRYTHVR 313
                 567.***********98 PP

  == domain 4  score: -2.8 bits;  conditional E-value: 2.2
     zf-C3H1   7 aGGvCnDp 14 
                 aG  C D+
  EEA18628.1 333 AG-ECTDR 339
                 56.99886 PP

  == domain 5  score: 4.7 bits;  conditional E-value: 0.01
     zf-C3H1   7 aGGvCnDpsCe 17 
                 +G vC++++C 
  EEA18628.1 350 TG-VCKKKKCT 359
                 45.*******7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (442 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1008  (0.0562218); expected 358.6 (0.02)
Passed bias filter:                      439  (0.0244855); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.58u 0.33s 00:00:00.90 Elapsed: 00:00:00.48
# Mc/sec: 2784.56
//
Query:       EEA18629.1  [L=661]
Description: bZIP transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.4e-08   32.8   8.9    5.4e-08   32.8   8.9    2.6  2  bZIP_1          bZIP transcription factor
    2.4e-06   27.5   5.7    2.4e-06   27.5   5.7    2.7  2  bZIP_2          Basic region leucine zipper
    2.2e-05   24.9  10.7    2.2e-05   24.9  10.7    3.6  4  bZIP_Maf        bZIP Maf transcription factor
  ------ inclusion threshold ------
      0.064   13.6   3.7        3.2    8.1   0.1    3.4  3  DUF4854         Domain of unknown function (DUF4854)


Domain annotation for each model (and alignments):
>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.8   8.9   1.2e-11   5.4e-08       2      53 ..     263     314 ..     262     331 .. 0.92
   2 ?    3.9   1.1     0.013        58      35      57 ..     356     378 ..     341     384 .. 0.65

  Alignments for each domain:
  == domain 1  score: 32.8 bits;  conditional E-value: 1.2e-11
                 XXXXXXXXX--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1   2 kelKrekrkqkNReaArrsRqRKqaeieeLerrvkaLekeNksLkseleelk 53 
                 kelK++kr+++NR aA  sRqRK+  +e+Le++ k++++  ++L + l ++k
  EEA18629.1 263 KELKQQKRLLRNRQAALDSRQRKKLHTEKLEEEKKQFTTVITDLEEALHSMK 314
                 89******************************************99998877 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.013
                 HHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  35 vkaLekeNksLkseleelkkeve 57 
                  ++L k+N  L++++e+++ + +
  EEA18629.1 356 TAELRKKNNILRETMEKMEQQFK 378
                 35555666666666666555555 PP

>> bZIP_2  Basic region leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.5   5.7   5.3e-10   2.4e-06       3      51 ..     264     313 ..     262     315 .. 0.90
   2 ?    3.7   2.8     0.014        64      35      54 .]     357     376 ..     354     376 .. 0.91

  Alignments for each domain:
  == domain 1  score: 27.5 bits;  conditional E-value: 5.3e-10
                 XXXXXXXX.XXXXXXXX-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_2   3 deyrerRr.kNreAarrsRekkkakeeeleervkeLeeeNaqLrqkveqL 51 
                 + + ++R  +Nr+Aa  sR++kk+++e+lee+ k+ ++ +  L++ + ++
  EEA18629.1 264 ELKQQKRLlRNRQAALDSRQRKKLHTEKLEEEKKQFTTVITDLEEALHSM 313
                 66889********************************9999999877665 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.014
                 HHHHHHHHHHHHHHHHHHHH CS
      bZIP_2  35 keLeeeNaqLrqkveqLeke 54 
                  eL+++N+ Lr+  e++e++
  EEA18629.1 357 AELRKKNNILRETMEKMEQQ 376
                 69***************986 PP

>> bZIP_Maf  bZIP Maf transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.9  10.7   4.9e-09   2.2e-05      20      83 ..     256     319 ..     247     329 .. 0.85
   2 ?   -0.4   0.1      0.37   1.6e+03      55      87 ..     319     351 ..     314     356 .. 0.84
   3 ?    2.9   0.8     0.035   1.6e+02      53      82 ..     356     385 ..     349     392 .. 0.84
   4 ?   -3.6   0.2       3.7   1.6e+04      56      64 ..     570     578 ..     554     596 .. 0.50

  Alignments for each domain:
  == domain 1  score: 24.9 bits;  conditional E-value: 4.9e-09
    bZIP_Maf  20 glteeeverLKqrRRrlKNrgyakscrkrrlqqkeelekekeeleeelerlqqelsrlrqekda 83 
                    eee+++LKq+ R l+Nr +a ++r+r+   +e+le+ek+++ +    l++ l  ++ ++ +
  EEA18629.1 256 STNEEEIKELKQQKRLLRNRQAALDSRQRKKLHTEKLEEEKKQFTTVITDLEEALHSMKIREGE 319
                 56799*****************************************999999999888755444 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.37
    bZIP_Maf  55 elekekeeleeelerlqqelsrlrqekdalkrk 87 
                 el +ek+e  +++++  q ++ lr ekd+l+r 
  EEA18629.1 319 ELLREKAEWLTTQQQYSQWIEGLRMEKDELIRV 351
                 6788999999999999999999****9999875 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.035
    bZIP_Maf  53 keelekekeeleeelerlqqelsrlrqekd 82 
                 + el+k+++ l+e++e+++q+ + + +++ 
  EEA18629.1 356 TAELRKKNNILRETMEKMEQQFKSMGHQQS 385
                 5689999999***********999988875 PP

  == domain 4  score: -3.6 bits;  conditional E-value: 3.7
    bZIP_Maf  56 lekekeele 64 
                 l ++++e e
  EEA18629.1 570 LPTKQQENE 578
                 333333333 PP

>> DUF4854  Domain of unknown function (DUF4854)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.1     0.031   1.4e+02      51      82 ..     280     311 ..     271     316 .. 0.84
   2 ?    8.1   0.1   0.00071       3.2      30      79 ..     341     386 ..     326     393 .. 0.85
   3 ?    1.1   0.0      0.11     5e+02      50      86 ..     541     578 ..     534     586 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.031
     DUF4854  51 aldalkealaesldsqastfeslakqlkkevk 82 
                 +  + k++ +e+l++++++f+ +  +l++++ 
  EEA18629.1 280 DSRQRKKLHTEKLEEEKKQFTTVITDLEEALH 311
                 5567899999*****************99875 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.00071
     DUF4854  30 vtaegntLvyeytlskslddaaldalkealaesldsqastfeslakqlkk 79 
                 ++ e ++L+   tl+++    +l + +++l e +++++++f+s+ +q  +
  EEA18629.1 341 LRMEKDELIRVHTLETA----ELRKKNNILRETMEKMEQQFKSMGHQQSN 386
                 667999********999....9999******************9988665 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.11
     DUF4854  50 aaldalkealaesldsqastfeslakqlkkevkv.enp 86 
                 a++++l+  +++   +qast+ +l ++l+  +k  en 
  EEA18629.1 541 AEMAHLTGSAHAHAHAQASTLDELHNNLALPTKQqENE 578
                 67888899999999*************99888875554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (661 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2036  (0.113559); expected 358.6 (0.02)
Passed bias filter:                      601  (0.0335211); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.78u 0.31s 00:00:01.09 Elapsed: 00:00:00.47
# Mc/sec: 4236.14
//
Query:       EEA18630.1  [L=557]
Description: pheromone response protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      8e-56  186.5   2.4    4.4e-12   46.4   0.1    7.4  7  RCC1        Regulator of chromosome condensation (RCC1) repea
    8.6e-43  143.3  21.1    6.9e-11   41.7   0.7    7.2  7  RCC1_2      Regulator of chromosome condensation (RCC1) repea
  ------ inclusion threshold ------
        7.4    5.2   5.2         10    4.8   5.2    1.1  1  Presenilin  Presenilin


Domain annotation for each model (and alignments):
>> RCC1  Regulator of chromosome condensation (RCC1) repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.7   0.0   3.8e-08   0.00023       3      50 .]     132     182 ..     132     182 .. 0.93
   2 !   20.6   0.0   8.9e-08   0.00053       1      50 []     185     262 ..     185     262 .. 0.65
   3 !   33.1   0.1   1.1e-11   6.3e-08       1      50 []     265     315 ..     265     315 .. 0.92
   4 !   42.3   0.0   1.4e-14   8.5e-11       1      50 []     318     370 ..     318     370 .. 0.84
   5 !   46.4   0.1   7.4e-16   4.4e-12       1      50 []     373     428 ..     373     428 .. 0.91
   6 ?    2.4   0.0     0.042   2.5e+02       5      50 .]     435     492 ..     432     492 .. 0.68
   7 !   12.1   0.1   3.9e-05      0.24       1      43 [.     495     539 ..     495     545 .. 0.67

  Alignments for each domain:
  == domain 1  score: 21.7 bits;  conditional E-value: 3.8e-08
                 EEEEEE--GGGTTSSSS-...--EEEEEE-GGGTTS-EEEEEEETTEEEEE CS
        RCC1   3 rVysWGrndyGqLGlgtt...esvlvPtkveglsgnrvvkvacGddhtval 50 
                 +V+++G+n++  LG g+t    +++ P+  + ls+  +v+++ G+ h +al
  EEA18630.1 132 DVFAFGSNSNAELGMGDTfkkADCPRPKFNSVLSDAGAVQISTGGMHGIAL 182
                 59****************988777999******999***********9886 PP

  == domain 2  score: 20.6 bits;  conditional E-value: 8.9e-08
                 TTEEEEEE--GGGTTSS.................SS---E............EEEEE-GGGTTS...-EEEEEEETTEEEEE CS
        RCC1   1 dGrVysWGrndyGqLGl.................gttesv............lvPtkveglsgn...rvvkvacGddhtval 50 
                 d +V++WG nd+G LG+                      +             +P+ + ++  +    +++v++ d+ ++al
  EEA18630.1 185 DNKVLTWGVNDQGALGRdtnwegglvdmekadesD----SdeeeeievnpkeATPSVIDLSGVEkgtVFTQVVAADSASFAL 262
                 568**************666666555555444331....0223345445444448888554433568999999999999986 PP

  == domain 3  score: 33.1 bits;  conditional E-value: 1.1e-11
                 TTEEEEEE..--GGGTTSSSS-..--EEEEEE-GGGTTS-EEEEEEETTEEEEE CS
        RCC1   1 dGrVysWG..rndyGqLGlgtt..esvlvPtkveglsgnrvvkvacGddhtval 50 
                 dG Vy+WG  rn++G  G  ++  + +++Pt+++gl+  +v+k+++G++h++al
  EEA18630.1 265 DGFVYGWGtfRNSNGVWGFSPEvmV-QNTPTLIPGLK--NVTKIVAGSNHVLAL 315
                 89********************753.358********..*************97 PP

  == domain 4  score: 42.3 bits;  conditional E-value: 1.4e-14
                 TTEEEEEE--GGGTTSSSS---E.....EEEEE-GGGTTS-EEEEEEETTEEEEE CS
        RCC1   1 dGrVysWGrndyGqLGlgttesv.....lvPtkveglsgnrvvkvacGddhtval 50 
                 dG VysWG++++ qL +   e++     l+P+kv + +   +v++a+G+dh++al
  EEA18630.1 318 DGTVYSWGSGEQDQLARRLVERRakeqgLIPQKVGSKR--GFVDIAAGADHSFAL 370
                 8****************6664444444599****6655..9************97 PP

  == domain 5  score: 46.4 bits;  conditional E-value: 7.4e-16
                 TTEEEEEE--GGGTTSSSS-..--E...EEEEE-GGGTTS.-EEEEEEETTEEEEE CS
        RCC1   1 dGrVysWGrndyGqLGlgtt..esv...lvPtkveglsgn.rvvkvacGddhtval 50 
                 dG+Vy+WG n+yGq G+ ++  es+   l+Pt +++l+g+ +++++++G++ t+a+
  EEA18630.1 373 DGSVYGWGLNNYGQTGIASKagESEagvLKPTVIPSLKGQnKITQISAGNFNTLAI 428
                 9****************7777655566799************************98 PP

  == domain 6  score: 2.4 bits;  conditional E-value: 0.042
                 EEEE--GGGTTSSSS-.........--EEEEEE-GGGTTS...-EEEEEEETTEEEEE CS
        RCC1   5 ysWGrndyGqLGlgtt.........esvlvPtkveglsgn...rvvkvacGddhtval 50 
                 + WGr d++  G+  +         ++++ P+ +++ ++    +v  ++ G  h +a+
  EEA18630.1 435 LVWGRIDNYATGIDAStlpkedvifDDRDRPRILTNATRIpnlEVAYATYGTEHAIAV 492
                 57888888888885555555334444446696666655446669**********9986 PP

  == domain 7  score: 12.1 bits;  conditional E-value: 3.9e-05
                 TTEEEEEE--GGGTTSSSS---EEEEEE-GGGTTS..-EEEEEEE CS
        RCC1   1 dGrVysWGrndyGqLGlgttesvlvPtkveglsgn..rvvkvacG 43 
                 dG+ ysWG+n+ +q G++ +++  v t++++   +  ++v + +G
  EEA18630.1 495 DGKAYSWGFNSSNQTGQPGDDDIKVATLINSKAVQekKFVWAGAG 539
                 8***************98876664444443322225555555555 PP

>> RCC1_2  Regulator of chromosome condensation (RCC1) repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0     0.042   2.5e+02      19      28 ..     132     141 ..     130     142 .. 0.90
   2 !   23.5   0.3   5.5e-09   3.3e-05       2      29 ..     170     197 ..     169     198 .. 0.94
   3 !   12.1   0.2   2.1e-05      0.13       8      29 ..     256     279 ..     249     279 .. 0.83
   4 !   31.0   0.1   2.6e-11   1.5e-07       1      26 [.     302     327 ..     302     331 .. 0.92
   5 !   41.7   0.7   1.2e-14   6.9e-11       2      30 .]     358     386 ..     357     386 .. 0.97
   6 !   23.2   0.0   6.9e-09   4.1e-05       1      25 [.     415     439 ..     415     444 .. 0.90
   7 !   19.8   0.1   8.6e-08   0.00051       8      30 .]     486     508 ..     480     508 .. 0.91

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.042
      RCC1_2  19 eVlcWGsNsd 28 
                 +V+++GsNs+
  EEA18630.1 132 DVFAFGSNSN 141
                 69******96 PP

  == domain 2  score: 23.5 bits;  conditional E-value: 5.5e-09
      RCC1_2   2 ksvsaGdyHscaLtedGeVlcWGsNsdG 29 
                 +++s G+ H +aLt d++Vl+WG N+ G
  EEA18630.1 170 VQISTGGMHGIALTHDNKVLTWGVNDQG 197
                 79**********************9877 PP

  == domain 3  score: 12.1 bits;  conditional E-value: 2.1e-05
      RCC1_2   8 dyHscaLtedGeVlcWG..sNsdG 29 
                 d+ s+aLt+dG V++WG  +Ns+G
  EEA18630.1 256 DSASFALTDDGFVYGWGtfRNSNG 279
                 6679*************7779998 PP

  == domain 4  score: 31.0 bits;  conditional E-value: 2.6e-11
      RCC1_2   1 VksvsaGdyHscaLtedGeVlcWGsN 26 
                 V+++ aG++H +aL++dG+V++WGs 
  EEA18630.1 302 VTKIVAGSNHVLALLTDGTVYSWGSG 327
                 789*********************96 PP

  == domain 5  score: 41.7 bits;  conditional E-value: 1.2e-14
      RCC1_2   2 ksvsaGdyHscaLtedGeVlcWGsNsdGQ 30 
                 ++++aG++Hs+aL+ dG V++WG N++GQ
  EEA18630.1 358 VDIAAGADHSFALHKDGSVYGWGLNNYGQ 386
                 79**************************9 PP

  == domain 6  score: 23.2 bits;  conditional E-value: 6.9e-09
      RCC1_2   1 VksvsaGdyHscaLtedGeVlcWGs 25 
                 ++++saG++ ++a+t+ +e l WG+
  EEA18630.1 415 ITQISAGNFNTLAITDKNECLVWGR 439
                 789*********************6 PP

  == domain 7  score: 19.8 bits;  conditional E-value: 8.6e-08
      RCC1_2   8 dyHscaLtedGeVlcWGsNsdGQ 30 
                   H++a+t+dG+ ++WG Ns+ Q
  EEA18630.1 486 TEHAIAVTTDGKAYSWGFNSSNQ 508
                 57******************988 PP

>> Presenilin  Presenilin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   5.2    0.0017        10     246     328 ..      28     148 ..       2     150 .. 0.31

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0017
  Presenilin 246 eeasesskeeeseeesseksaqsseseeeseeesseaessaeesseekeseessesseeeeeeeeeeeeses........................... 317
                 ++a++++++ +++++s  ++++ +es++  +e++ +++++ +++++ +e+ + +++++ e+++        +                           
  EEA18630.1  28 AAAEKKTTTIATTKKSIATTKKPAESKKPLQEAKPNTSAKRKAEADLEEKPQGKRQKQVETKAV-------Kkervikkpttpraktpkpapapkppkk 119
                 1111111111111111111111111222222222222222222222222222221111111111.......1112222244444445555555555555 PP

  Presenilin 318 ..................eergvkLGLGD 328
                                    ++   LG+GD
  EEA18630.1 120 kvvintapttrldvfafgSNSNAELGMGD 148
                 55555555555555555544566666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (557 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1058  (0.0590105); expected 358.6 (0.02)
Passed bias filter:                      456  (0.0254337); expected 358.6 (0.02)
Passed Vit filter:                        75  (0.00418317); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.76u 0.31s 00:00:01.07 Elapsed: 00:00:00.50
# Mc/sec: 3360.84
//
Query:       EEA18631.1  [L=415]
Description: formamidase FmdS [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
   4.2e-174  578.7   0.0   4.8e-174  578.5   0.0    1.0  1  FmdA_AmdA  Acetamidase/Formamidase family


Domain annotation for each model (and alignments):
>> FmdA_AmdA  Acetamidase/Formamidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  578.5   0.0  2.7e-178  4.8e-174       2     372 ..      10     393 ..       9     394 .. 0.98

  Alignments for each domain:
  == domain 1  score: 578.5 bits;  conditional E-value: 2.7e-178
   FmdA_AmdA   2 vdlskpaaeqeeklhNRwHpdipavaevkpgetvkvecldwtdgqiknndsaddvrtvdlkkvHeltgPvevegAepGDllvveildievleeaewGyt 100
                 vd+++pa++q + lhNRwHpd+p++ +++++etvk+ecldwt+gqi+nndsaddv +vdl+k+H+l+gP+e+egAepGD+l+vei+d++++e+++wG++
  EEA18631.1  10 VDVNTPAEKQ-PYLHNRWHPDVPFCGKIRNNETVKIECLDWTGGQIGNNDSADDVLNVDLTKIHYLSGPFEIEGAEPGDVLCVEIQDVQPFEDQPWGFS 107
                 7889999988.8*************************************************************************************** PP

   FmdA_AmdA 101 gifdkenggGflkdafpeaakaiwdlegiyassrqipgvrfrglphpGllGtapskelldswnareeeliek.......ralallpepkeallgklee. 191
                 g+f+kenggGfl++++p+aakaiwd+egi+++sr+ipgv+f+gl+hpG+lG+aps+e+l++wn+re+eli++       r++a++p ++++++g +++ 
  EEA18631.1 108 GVFHKENGGGFLDEIYPNAAKAIWDFEGIHCTSRHIPGVKFAGLIHPGILGCAPSAEILAEWNRREAELISEkaasgttRTVANPPLTTNTHAGVADKa 206
                 **********************************************************************999*********************99777 PP

   FmdA_AmdA 192 eaekvaaegartvppr.engGnmDiknlsrGskvylPVkveGaklsvGDlHfsqGDGEisfcgaiemsgvvtlkvevikggmeklgi...knpiflpee 286
                 +a+k+aaegartvp+r e+gGn+DiknlsrGskvylPV+v+Gak+svGDlHfsqGDGEisfcgaiem+gv+t+k++v+k+g ++lg+   k+pif+p++
  EEA18631.1 207 TAAKIAAEGARTVPGRpEHGGNCDIKNLSRGSKVYLPVHVPGAKFSVGDLHFSQGDGEISFCGAIEMAGVITVKCTVMKDGQKQLGMvngKSPIFIPGP 305
                 *********************************************************************************99996533379******* PP

   FmdA_AmdA 287 vepry..seylsfeGisvdesgkqhyldltvAyrnallraieyLkkfGytkeqaylllsvapvegrisgivdiPnvvatlalPldiFd 372
                 v+p++   ++l+feG+svde+gkqh+ld+t+Ayr+++lr+ieyLk++Gy+++q+yllls+apveg+i+givdiPn+++t+ lP+diF+
  EEA18631.1 306 VQPQFgpGRMLYFEGFSVDENGKQHFLDATIAYRQSCLRIIEYLKRYGYDDYQIYLLLSAAPVEGHIAGIVDIPNACTTIGLPMDIFE 393
                 *****999*******************************************************************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (415 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       366  (0.0204139); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.35s 00:00:01.00 Elapsed: 00:00:00.56
# Mc/sec: 2238.84
//
Query:       EEA18632.1  [L=396]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.7e-14   51.5   6.1    3.1e-05   24.5   0.1    3.7  3  Sel1      Sel1 repeat
  ------ inclusion threshold ------
       0.62   10.5   8.3        1.2    9.6   8.3    1.4  1  NUDE_C    NUDE protein, C-terminal conserved region
          1    8.7   4.7        1.7    8.0   4.7    1.3  1  DUF908    Domain of Unknown Function (DUF908)


Domain annotation for each model (and alignments):
>> Sel1  Sel1 repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.6   0.0   0.00012      0.73       3      35 ..     254     284 ..     252     286 .. 0.85
   2 !   24.5   0.1   5.1e-09   3.1e-05       3      38 .]     311     344 ..     309     344 .. 0.95
   3 !   17.3   1.0   9.6e-07    0.0058       2      38 .]     346     380 ..     345     380 .. 0.93

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00012
        Sel1   3 AmyrLGmfylylnGlgvpkDpekAiewyekAAe 35 
                 A+  +G  +++ +G g  +D  kA+ ++  AA 
  EEA18632.1 254 AQVLYG--LALRHGWGCTPDLPKAVIYLSAAAT 284
                 777777..666********************96 PP

  == domain 2  score: 24.5 bits;  conditional E-value: 5.1e-09
        Sel1   3 AmyrLGmfylylnGlgvpkDpekAiewyekAAeqGd 38 
                 A y L+   ++ nG g++kDp+ A+ +ye AA++Gd
  EEA18632.1 311 AIYELA--NCFRNGWGIDKDPIAARLYYETAANLGD 344
                 89****..999***********************97 PP

  == domain 3  score: 17.3 bits;  conditional E-value: 9.6e-07
        Sel1   2 eAmyrLGmfylylnGlgvpkDpekAiewyekAAeqGd 38 
                 +Am+  +   +yl+G g +kD+  A ++y++A ++G+
  EEA18632.1 346 DAMNECA--WCYLEGFGGKKDKYTAAKYYRLAEQNGN 380
                 79*****..***********************88876 PP

>> NUDE_C  NUDE protein, C-terminal conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   8.3    0.0002       1.2      73     166 ..      20     119 ..       7     127 .. 0.71

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0002
      NUDE_C  73 lsspstpqsleiekrspavqasssPviatppekslsslatgsetatppsPpasessdllrkvlal..tsklarqrasisdsaask....rsnsrslrss 165
                 ++ p+tpq+ +  ++++ +q + +P + ++  +++ ++  ++e+++p +P  s + + +r+  +   t +la+   s s+++ s+     ++srs+ s 
  EEA18632.1  20 VHPPTTPQEFTFIRTDTYTQETITPAAINTSITNIAAAGPTEEAQSPTTPTTSRRKSFFRRRSHIssTENLASPPRSGSEKSISNllhlDHHSRSSLSR 118
                 46799********************986666666444444488899999999888877777655433889*********99888887754444433333 PP

      NUDE_C 166 r 166
                 +
  EEA18632.1 119 S 119
                 3 PP

>> DUF908  Domain of Unknown Function (DUF908)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   4.7   0.00028       1.7     142     225 ..      29     117 ..      13     135 .. 0.63

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00028
      DUF908 142 vtYYkkssseeqkaesksskeeasesli.........ssspstPtplrrssklgktssspsspaktstpskaaksqeglktfeipesevssks 225
                 +t+ ++++ ++++ +++  +++ +   +          +sp+tPt++rr+s   ++s   ss+++  +p+ + ++++ +++++++ ++ ss s
  EEA18632.1  29 FTFIRTDTYTQETITPAAINTSIT---NiaaagpteeAQSPTTPTTSRRKSFFRRRS-HISSTENLASPPRSGSEKSISNLLHLDHHSRSSLS 117
                 555555555554444443222222...135577777899************999854.23333445556666666666678888888777643 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (396 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       488  (0.0272185); expected 358.6 (0.02)
Passed bias filter:                      317  (0.0176809); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.68u 0.32s 00:00:01.00 Elapsed: 00:00:00.56
# Mc/sec: 2133.72
//
Query:       EEA18633.1  [L=242]
Description: mitochondrial ATPase subunit ATP4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-52  177.7   5.4    1.7e-52  177.3   5.4    1.1  1  Mt_ATP-synt_B  Mitochondrial ATP synthase B chain precursor (
      0.008   14.5   2.7     0.0098   14.2   2.7    1.1  1  Virul_Fac      Putative bacterial virulence factor
  ------ inclusion threshold ------
      0.042   13.9   0.5      0.077   13.1   0.5    1.4  1  DUF1539        Domain of Unknown Function (DUF1539)


Domain annotation for each model (and alignments):
>> Mt_ATP-synt_B  Mitochondrial ATP synthase B chain precursor (ATP-synt_B)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  177.3   5.4   2.8e-56   1.7e-52       2     163 .]      75     236 ..      74     236 .. 0.99

  Alignments for each domain:
  == domain 1  score: 177.3 bits;  conditional E-value: 2.8e-56
                    HHHHHHCCCSS--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHH CS
  Mt_ATP-synt_B   2 iayliSkeiyvvneEtlvalcfigflilvakslgpsikefldkriekiqeelnqsrnlkeealkerieqekklqslveltkslfevskeqvaleae 97 
                     +++iS+e+yv+neEt+ a+c++ +++++ k++gp++ e++d++ +k++++ln++r+++++a+k rie++++l  +ve+tk+lfevske+++lea+
     EEA18633.1  75 SIAAISNELYVLNEETVIAFCLLSVFTALGKYGGPAYREWADGQSQKYKDILNSARADHTNAVKARIENVQQLGGVVEVTKQLFEVSKETAKLEAQ 170
                    799********************************************************************************************* PP

                    HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHCTCCCCHHHHHHHHHHHHH CS
  Mt_ATP-synt_B  98 aferelqaklareikkkldtlvnaessrrqrlQdelvkgvissVlkelsspkfkkevlqesiadle 163
                    a+e+e++++la+e+k++ld++v++e +++qr+Q+el+++vi ++ +el++pk  +++lq+siad+e
     EEA18633.1 171 AYELEQRTALAAEAKQVLDSWVRYEGQVKQREQRELAETVIRKIHEELKNPKVLQQILQQSIADVE 236
                    ****************************************************************97 PP

>> Virul_Fac  Putative bacterial virulence factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   2.7   1.6e-06    0.0098     543     623 ..     148     230 ..     127     241 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 1.6e-06
   Virul_Fac 543 GGvsrlaekLekvakpelKlerieeqldeiaeel..vearLaayyqaddaeevekkkklaeeilkalektlekaklfgelLka 623
                 GGv  ++++L +v+k+ +Kle  + +l++ ++     ++ L+++ + +++ + +++++lae++++++++ l++ k++ ++L++
  EEA18633.1 148 GGVVEVTKQLFEVSKETAKLEAQAYELEQRTALAaeAKQVLDSWVRYEGQVKQREQRELAETVIRKIHEELKNPKVLQQILQQ 230
                 9*******************98876666554322124899****************************999999999999986 PP

>> DUF1539  Domain of Unknown Function (DUF1539)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.5   1.3e-05     0.077      23      84 ..     165     226 ..     150     236 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.3e-05
     DUF1539  23 nrkLekeikklaqn..lrdeWkkilkylskkesseveseeaqalfrstlkkllelLkdptiske 84 
                   kLe +  +l q   l  e k++l+      +++v+++e+ +l+++++ k++e Lk+p++ ++
  EEA18633.1 165 A-KLEAQAYELEQRtaLAAEAKQVLDSWVR-YEGQVKQREQRELAETVIRKIHEELKNPKVLQQ 226
                 3.5888888888877899999*****9999.9****************************9776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (242 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1401  (0.0781416); expected 358.6 (0.02)
Passed bias filter:                      592  (0.0330191); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.34s 00:00:00.99 Elapsed: 00:00:00.56
# Mc/sec: 1311.69
//
Query:       EEA18634.1  [L=560]
Description: ribosome biogenesis protein Noc4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.8e-38  131.6   1.1    6.8e-38  130.4   1.1    1.7  1  CBF       CBF/Mak21 family
  ------ inclusion threshold ------
        3.5    7.3   6.8        7.3    6.3   6.8    1.5  1  ATP11     ATP11 protein


Domain annotation for each model (and alignments):
>> CBF  CBF/Mak21 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  130.4   1.1   7.6e-42   6.8e-38       2     170 .]     322     479 ..     321     479 .. 0.88

  Alignments for each domain:
  == domain 1  score: 130.4 bits;  conditional E-value: 7.6e-42
         CBF   2 vqaLvllfqllskqkqsel.lsasdRFyraLYrkLldpelltsskralllnlly.....kalkadkpvkrvaAFvKRllqlalhappsfalgllallse 94 
                 ++aL+ lf l+++    +l ++    Fy++LY++L d+ell+s++r+++++ll+     ++l    p+++va+FvKRl++lal+apps +++++ + ++
  EEA18634.1 322 LLALSGLFYLIQER---NLdYPH---FYTKLYSLL-DSELLHSKHRSRFFRLLDtflgsTHL----PATLVASFVKRLARLALNAPPSAIVAIVPFAYN 409
                 79***********5...455777...*********.******************87777777....********************************* PP

         CBF  95 llkhppklkalleekfkdvkeeeeeekkeekkkskaesgvYdptkrdpeysnaeasslwElsllakhfhPtValfA 170
                 llk++p++  +++   +d++++ ++++    +++   s+++ + ++dp  ++a +sslwEl+ l++h+hP+Va++A
  EEA18634.1 410 LLKSHPTCTFMIH---RDISNDTKKKAT--IEAQG-MSDPFMADETDPTLTRAMESSLWELESLQSHYHPNVAAIA 479
                 ***999*******...676666433222..23333.39*****99****************************987 PP

>> ATP11  ATP11 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   6.8   0.00082       7.3      31     102 ..       3      74 ..       1      79 [. 0.73

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.00082
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---.......SS--HHHHS-HHHHTTS-H CS
       ATP11  31 dkieekrkeaaaidleesksesekekeakasssektekkesaakskkkskskspvkpLssildleklkelpa 102
                 ++i++krk  +  ++e+++s+++++ ++++s++e+t+ +e +a+ ++++k  +++ +L s+l+++ +k+ ++
  EEA18634.1   3 KEITKKRKIPKDSTSESKTSSKRRAVASDQSKNEQTKIEELEAQISESRKYYNNIATLISMLNVDNIKDNNE 74 
                 567777776655556666666666666666666666666666666699********************9765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (560 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1215  (0.0677673); expected 358.6 (0.02)
Passed bias filter:                      654  (0.0364772); expected 358.6 (0.02)
Passed Vit filter:                        67  (0.00373696); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.81u 0.36s 00:00:01.17 Elapsed: 00:00:00.56
# Mc/sec: 2993.72
//
Query:       EEA18635.1  [L=275]
Description: extracellular matrix protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.5e-11   44.9   0.0    1.5e-11   44.9   0.0    2.9  2  GPI-anchored  Ser-Thr-rich glycosyl-phosphatidyl-inositol-anc
     0.0011   18.6   0.0      0.002   17.7   0.0    1.4  1  DUF3301       Protein of unknown function (DUF3301)


Domain annotation for each model (and alignments):
>> GPI-anchored  Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.9   0.0   1.7e-15   1.5e-11       9      89 ..      31     104 ..      26     108 .. 0.91
   2 ?   -8.7  10.9         2   1.8e+04      25      38 ..     162     175 ..     114     252 .. 0.67

  Alignments for each domain:
  == domain 1  score: 44.9 bits;  conditional E-value: 1.7e-15
  GPI-anchored   9 vtagkpvtitWkdsgtdpgtvtlvLcagssnnlksvktiasgiknsdgsytwtvpaslesggaYflqivsesnegiynySd 89 
                   + ag+pv ++W +      + t++L++g+s++l++v+ + ++++n  g+++wt+p++l++g++Y+++i++++++   ny+ 
    EEA18635.1  31 LVAGEPVMLRWMG--GNGAPATITLRKGQSTDLQDVQVLSKDANN--GEFSWTPPTDLQNGDNYAFEISQGDEN---NYTG 104
                   679**********..46899**********************988..6*********************99999...8876 PP

  == domain 2  score: -8.7 bits;  conditional E-value: 2
  GPI-anchored  25 dpgtvtlvLcagss 38 
                   + + +t  L +g++
    EEA18635.1 162 TGTDTTSALSSGTT 175
                   33333333333333 PP

>> DUF3301  Protein of unknown function (DUF3301)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0   2.3e-07     0.002      33      86 ..      60     111 ..      50     114 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 2.3e-07
     DUF3301  33 ekldlqLLdeavalrrlrlkrdargrlrlrrvYeFEFSsdGedryeGeivllGk 86 
                 + +d+q L++   + +++  +++ + l+    Y+FE S+ +e++y+G+++++G 
  EEA18635.1  60 DLQDVQVLSKDANNGEFS--WTPPTDLQNGDNYAFEISQGDENNYTGSLSMTGG 111
                 568999999988887777..556999*************************995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1274  (0.0710581); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.79u 0.40s 00:00:01.19 Elapsed: 00:00:00.56
# Mc/sec: 1488.30
//
Query:       EEA18636.1  [L=355]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.8e-05   22.5  28.3       0.05   13.3  19.3    2.2  2  SHE3           SWI5-dependent HO expression protein 3
  ------ inclusion threshold ------
      0.021   14.9   1.6      0.021   14.9   1.6    3.5  4  TolA_bind_tri  TolA binding protein trimerisation
       0.04   14.1  31.4       0.61   10.3  17.5    2.9  2  Jnk-SapK_ap_N  JNK_SAPK-associated protein-1
       0.04   14.4   4.0       0.04   14.4   4.0    4.2  2  ZapB           Cell division protein ZapB
      0.062   12.2  35.1      0.098   11.5  15.0    2.1  2  Spc7           Spc7 kinetochore protein
       0.16   11.8   0.4       0.39   10.6   0.1    1.7  2  Vip3A_N        Vegetative insecticide protein 3A N terminal
       0.52   10.3  25.9      0.042   13.8   4.8    3.5  4  FlxA           FlxA-like protein
        2.5    8.5  31.1         12    6.3  20.6    3.4  3  HrpB7          Bacterial type III secretion protein (HrpB7)
        3.2    7.8  36.6       0.87    9.7  12.4    3.3  4  ADIP           Afadin- and alpha -actinin-Binding
        5.9    6.5  39.5        6.9    6.3  12.1    2.7  2  Lebercilin     Ciliary protein causing Leber congenital amaur


Domain annotation for each model (and alignments):
>> SHE3  SWI5-dependent HO expression protein 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.3  19.3   2.8e-05      0.05       1     150 [.     115     268 ..     115     276 .. 0.80
   2 !   12.6   5.2   4.6e-05     0.083      92     186 ..     249     346 ..     242     352 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 2.8e-05
                 XXHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
        SHE3   1 StkVIesLHeqiDaLtktnlqLtqqsqeLleklelaqkkeskflenlaslkhENdnLsslLkRKerrlkdlekelselkesveelklekkqlkkrlens 99 
                 S++VI +L e+i  Lt+++   +   +e  +  e+ +++  ++ e l +  + N+   + + RK+r++ dl  e+++ k++   +++e+ ++++ + + 
  EEA18636.1 115 SGRVIHNLQEEIARLTRELSLYRSRAEEAQHINETLKEQIINISERLRNSEQSNETNLASIARKDRKIEDLRAEVQNEKSRRLRAEAETAKVNQLMSEE 213
                 89****************98888888888888889999999999**********97777789************9999998877777777777777666 PP

                 CCHHHHHHHHHHHHHH....HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        SHE3 100 saseteleeelerlkv....qYdalvdsqkeYkehYqqeieeLkesleklklene 150
                 +++ ++  +el+++ +    qYd l ++  + ++  q++ + ++ +l +l+ + e
  EEA18636.1 214 QDEFHRKCAELQEMSNystsQYDVLSKTSLRERSDMQRKFKGIRDELASLRDQAE 268
                 666666666666664323339**99999999999999988888888888876554 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 4.6e-05
                 HHHHHHHCCCHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXX CS
        SHE3  92 lkkrlenssaseteleeele...rlkvqYdalvdsqkeYkehYqqeieeLkesleklklenekqleelqerissndkdidtkldsynnkkknlesiee 186
                 ++ +++   ++ ++l+++ e   r +   dal++ q++  e  ++ i+e+ ++ +++k+ +++++e+l ++  +n+ ++d+ + s+++   +++ + +
  EEA18636.1 249 MQRKFKGIRDELASLRDQAElkdREQERLDALINRQNQELETERRRIQEIFTAYDTYKTARDREFEDLLTKGRQNQANVDAAVASLKETEDKMKWVMH 346
                 55555555555555555543112456678************************************************************999997654 PP

>> TolA_bind_tri  TolA binding protein trimerisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   1.6   1.2e-05     0.021      17      74 ..     116     169 ..     108     171 .. 0.86
   2 ?   -1.1   0.3       1.1   2.1e+03      35      44 ..     195     204 ..     179     234 .. 0.55
   3 ?    3.3   9.9     0.048        85      18      67 ..     244     296 ..     219     304 .. 0.76
   4 ?   -3.5   0.0       6.6   1.2e+04      49      70 ..     314     335 ..     311     339 .. 0.60

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.2e-05
  TolA_bind_tri  17 sqlllelqqqlealqqelreLRGqiEelqyqleqleerQrdlYldlDerlrkleagga 74 
                     +++++lq+++ +l +el+  R   Ee q+ +e+l+    ++ +++ erlr +e++++
     EEA18636.1 116 GRVIHNLQEEIARLTRELSLYRSRAEEAQHINETLK----EQIINISERLRNSEQSNE 169
                    58999*************************888875....668999999999998876 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 1.1
  TolA_bind_tri  35 reLRGqiEel 44 
                    r+LR + E  
     EEA18636.1 195 RRLRAEAETA 204
                    4555555543 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.048
  TolA_bind_tri  18 qlllelqqqlealqqelreLRGqiE...elqyqleqleerQrdlYldlDerlr 67 
                    +   ++q++ +  + el++LR q E   + q +l+ l++rQ++  +   +r++
     EEA18636.1 244 RERSDMQRKFKGIRDELASLRDQAElkdREQERLDALINRQNQELETERRRIQ 296
                    66789*******************93334566677778888776555444544 PP

  == domain 4  score: -3.5 bits;  conditional E-value: 6.6
  TolA_bind_tri  49 eqleerQrdlYldlDerlrkle 70 
                    e+l+++ r+   ++D+ +++l+
     EEA18636.1 314 EDLLTKGRQNQANVDAAVASLK 335
                    5556666666666666666665 PP

>> Jnk-SapK_ap_N  JNK_SAPK-associated protein-1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3  17.5   0.00034      0.61      26     123 ..     149     242 ..     140     274 .. 0.77
   2 ?   10.0   4.2   0.00041      0.73      36     107 ..     275     343 ..     274     352 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00034
  Jnk-SapK_ap_N  26 gLmPkvVkvLElLeslasrneeeeaeleelreeleqLeteyerekelrkraeeeleeiedqweeerkelqekveqleeenrelelkaknaadqlsr 121
                    +L  +++++ E L +  + ne + a + +  +++e+L+ e ++ek+ r rae e  ++ + + ee+ e++ k ++l+e  +       ++ d ls+
     EEA18636.1 149 TLKEQIINISERLRNSEQSNETNLASIARKDRKIEDLRAEVQNEKSRRLRAEAETAKVNQLMSEEQDEFHRKCAELQEMSNYST----SQYDVLSK 240
                    566789***********************************************************************8655444....22233333 PP

  Jnk-SapK_ap_N 122 le 123
                     +
     EEA18636.1 241 TS 242
                    33 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00041
  Jnk-SapK_ap_N  36 ElLeslasrneeeeaeleelreeleqLeteyerekelrkraeeeleeiedqweeerkelqekveqleeenre 107
                    E L++l++r+   ++ele  r+ ++++ t y+  k +r r+ e+l+ +  q + +  +  + ++++e++++ 
     EEA18636.1 275 ERLDALINRQ---NQELETERRRIQEIFTAYDTYKTARDREFEDLLTKGRQNQANVDAAVASLKETEDKMKW 343
                    7899998886...99********************9999999999888888888877777777777766654 PP

>> ZapB  Cell division protein ZapB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   4.0   2.2e-05      0.04      20      64 ..     119     163 ..     118     164 .. 0.96
   2 ?  -16.6  24.9        10   1.8e+04      24      59 ..     257     296 ..     165     348 .. 0.75

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 2.2e-05
        ZapB  20 itlLqmeieeLkeeneelkeenreleeeneqlkeereawqerlkk 64 
                 i  Lq+ei++L +e + + ++++e ++ ne lke+  ++ erl++
  EEA18636.1 119 IHNLQEEIARLTRELSLYRSRAEEAQHINETLKEQIINISERLRN 163
                 789***************************************986 PP

  == domain 2  score: -16.6 bits;  conditional E-value: 10
        ZapB  24 qmeieeLkeeneelkeenrele....eeneqlkeereawq 59 
                 + e++ L+ + e   +e+++l     ++n++l++er  +q
  EEA18636.1 257 RDELASLRDQAELKDREQERLDalinRQNQELETERRRIQ 296
                 3334444433333333333333444466666666655555 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6  15.4    0.0018       3.1     168     261 ..     118     214 ..     112     217 .. 0.91
   2 ?   11.5  15.0   5.5e-05     0.098     149     286 ..     208     345 ..     204     352 .. 0.89

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.0018
        Spc7 168 llpeleeekaeleeeleklqeaaeelesid...keeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaervleeck 261
                 + ++l+ee a+l++el   +++aee + i+   ke++ ++ e+l++ ++  e   + +a++ +++e+l++++++ k+++ ++e+e+a+ ++++ e++
  EEA18636.1 118 VIHNLQEEIARLTRELSLYRSRAEEAQHINetlKEQIINISERLRNSEQSNETNLASIARKDRKIEDLRAEVQNEKSRRLRAEAETAKVNQLMSEEQ 214
                 67899****************99888886655699****************************************************9999988765 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 5.5e-05
        Spc7 149 egleedkelLekqeeeldellpeleeekaeleeeleklqe.aaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqksel 246
                 + + e++++ +++ +el+e+ +  +++++ l+++  ++++ ++++++   ++eL++lr++ +  + e e++ + +++ +++le+ + +i+e+ + ++++
  EEA18636.1 208 QLMSEEQDEFHRKCAELQEMSNYSTSQYDVLSKTSLRERSdMQRKFKG-IRDELASLRDQAELKDREQERLDALINRQNQELETERRRIQEIFTAYDTY 305
                 679999***************************998888834555554.589*********************************************** PP

        Spc7 247 eeeiaeaervleeckgwsesevsrlkeevkaleeltgwki 286
                 +++  ++ + l  + + ++ +v++  +++k+ e++ +w +
  EEA18636.1 306 KTARDREFEDLLTKGRQNQANVDAAVASLKETEDKMKWVM 345
                 999888877777788888999***************9965 PP

>> Vip3A_N  Vegetative insecticide protein 3A N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       1.5   2.7e+03      99      99 ..     146     146 ..      78     185 .. 0.61
   2 ?   10.6   0.1   0.00022      0.39      48     143 ..     247     342 ..     232     351 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 1.5
     Vip3A_N  99 i 99 
                 i
  EEA18636.1 146 I 146
                 1 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00022
     Vip3A_N  48 ndisgkldgvngslndliaqgnlntelskeilkianeqnqvlndvnnkldaintmlrvylpkitsmlsdvmkqnyalslqieylskqlqeisdkld 143
                  d+  k+ g+  +l+ l  q +l+ +   ++  + n qnq l+    +++ i t   +y       ++d++ +      +++     l+e  dk+ 
  EEA18636.1 247 SDMQRKFKGIRDELASLRDQAELKDREQERLDALINRQNQELETERRRIQEIFTAYDTYKTARDREFEDLLTKGRQNQANVDAAVASLKETEDKMK 342
                 477889*****************************************************9999999999988888888888888888888888875 PP

>> FlxA  FlxA-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.1         3   5.4e+03      75      86 ..      21      32 ..      11      40 .. 0.43
   2 ?   13.8   4.8   2.3e-05     0.042       4      87 ..     104     181 ..     101     196 .. 0.76
   3 ?   -1.1  10.1       1.1   1.9e+03      20      85 ..     148     209 ..     136     236 .. 0.61
   4 ?    7.8   4.9    0.0018       3.3      10      69 ..     237     296 ..     227     300 .. 0.86

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 3
        FlxA 75 kaqekqqsekee 86
                k++++ +s+ ++
  EEA18636.1 21 KQKKEPSSTDDD 32
                333333333222 PP

  == domain 2  score: 13.8 bits;  conditional E-value: 2.3e-05
        FlxA   4 ssasssssssgsasqiasLqkQiknlqkqLkelsesdeltkeekkkqqqliqaQIqqlqaQIaqlqqqqaekaqekqqsekeek 87 
                 +sa+  +s+ +s   i +Lq++i++l+ +L+   +     +ee +   +++++QI ++   ++    +q+++++ ++   k++k
  EEA18636.1 104 TSAVGHASTGKSGRVIHNLQEEIARLTRELSLYRSR----AEEAQHINETLKEQIINISERLRNS--EQSNETNLASIARKDRK 181
                 788999999*********************877777....777889**************99875..45555555444444444 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 1.1
        FlxA  20 asLqkQiknlqkqLkelsesdeltkeekkkqqqliqaQIqqlqaQIaqlqqqqaekaqekqqseke 85 
                 ++L++Qi n+++ L++  +s    +e   + +     +I++l+a+++  ++   + ++e+++ ++ 
  EEA18636.1 148 ETLKEQIINISERLRNSEQS----NETNLASIARKDRKIEDLRAEVQNEKSRRLRAEAETAKVNQL 209
                 57888888888888876666....333335666666777777777766665554444444443333 PP

  == domain 4  score: 7.8 bits;  conditional E-value: 0.0018
        FlxA  10 ssssgsasqiasLqkQiknlqkqLkelsesdeltkeekkkqqqliqaQIqqlqaQIaqlq 69 
                   s++s  + + +q+  k + ++L +l ++ el + e++    li  Q q l+ + +++q
  EEA18636.1 237 VLSKTSLRERSDMQRKFKGIRDELASLRDQAELKDREQERLDALINRQNQELETERRRIQ 296
                 4566777788899*****************************************999999 PP

>> HrpB7  Bacterial type III secretion protein (HrpB7)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.1     0.033        59     109     143 ..     119     153 ..     104     156 .. 0.83
   2 ?    6.3  20.6    0.0066        12      10     133 ..     175     298 ..     169     308 .. 0.71
   3 ?    5.1   0.9     0.016        28       4      47 ..     297     340 ..     293     350 .. 0.82

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.033
       HrpB7 109 vaatarkiaRndaqidacrerierlrraaerared 143
                 +   +++iaR+ +++  +r r+e ++   e  +e+
  EEA18636.1 119 IHNLQEEIARLTRELSLYRSRAEEAQHINETLKEQ 153
                 6777899***************9999877777765 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0066
       HrpB7  10 verrarreerlraeleaaraalaaaeaalaaaqaqveaardavraheerlddlttgsspfsiadylacr..ayrdvlegrvraaeaelaaarqaldaae 106
                 ++r+ r+ e lrae ++ + ++  aea+ a+ ++ +++++d+ ++  ++l+++   s   s  d+l+    + r+ ++ + +    ela +r++ + + 
  EEA18636.1 175 IARKDRKIEDLRAEVQNEKSRRLRAEAETAKVNQLMSEEQDEFHRKCAELQEMSNYST--SQYDVLSKTslRERSDMQRKFKGIRDELASLRDQAELKD 271
                 789*************************************************988774..333333333003344555555555556666666655555 PP

       HrpB7 107 davaatarkiaRndaqidacrerierl 133
                 ++ ++ ++ i R + +++  r+ri+ +
  EEA18636.1 272 REQERLDALINRQNQELETERRRIQEI 298
                 555555666666666666666666555 PP

  == domain 3  score: 5.1 bits;  conditional E-value: 0.016
       HrpB7   4 sawrtlverrarreerlraeleaaraalaaaeaalaaaqaqvea 47 
                  ++ +    ++ r+++ ++ l + r+++a+ +aa+a+ ++ +++
  EEA18636.1 297 EIFTAYDTYKTARDREFEDLLTKGRQNQANVDAAVASLKETEDK 340
                 5777777889999**********************998776655 PP

>> ADIP  Afadin- and alpha -actinin-Binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7  12.4   0.00048      0.87      62     139 ..     119     196 ..     114     201 .. 0.95
   2 ?    3.6  10.2     0.036        64      59     146 ..     191     277 ..     188     280 .. 0.88
   3 ?    4.5   7.5     0.019        33      80     146 ..     250     316 ..     245     324 .. 0.83
   4 ?    4.4   5.8      0.02        37      51     117 ..     273     340 ..     268     348 .. 0.64

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00048
        ADIP  62 irkleaeierlqskierlktqleqlerelalvqakerqlekklktleqklknekeelqrlknalqqiktqyahelkkk 139
                 i++l+ ei+rl+ + +    + e+ +  +++++++  ++  +l++ eq + +   +++r  ++++++++ +++e+ ++
  EEA18636.1 119 IHNLQEEIARLTRELSLYRSRAEEAQHINETLKEQIINISERLRNSEQSNETNLASIARKDRKIEDLRAEVQNEKSRR 196
                 899***********************************************************************9887 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.036
        ADIP  59 netirkleaeierlqskierlktqleqlerelalvqakerqlekklktleqklknekeelqrlknalqqiktqyahelkkkdreiekL 146
                 ne+ r+l+ae e   +  + ++++  +++r++a +q+  +  + ++  l+++  +e+ ++qr  + + +  ++++     kdre e+L
  EEA18636.1 191 NEKSRRLRAEAET-AKVNQLMSEEQDEFHRKCAELQEMSNYSTSQYDVLSKTSLRERSDMQRKFKGIRDELASLRDQAELKDREQERL 277
                 8999******999.77778888****************************************99998888888887777777777666 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.019
        ADIP  80 ktqleqlerelalvqakerqlekklktleqklknekeelqrlknalqqiktqyahelkkkdreiekL 146
                 +++ +  + ela++  +     +++++l++ ++++ +el+  ++ +q+i t+y  ++  +dre e L
  EEA18636.1 250 QRKFKGIRDELASLRDQAELKDREQERLDALINRQNQELETERRRIQEIFTAYDTYKTARDREFEDL 316
                 555666667777776666667789999999********************************99987 PP

  == domain 4  score: 4.4 bits;  conditional E-value: 0.02
        ADIP  51 dleqre.slnetirkleaeierlqskierlktqleqlerelalvqakerqlekklktleqklknekee 117
                 ++e    + n+++++le+e  r q  +   +t  ++ +re + +  k rq+++++ ++ + lk++ ++
  EEA18636.1 273 EQERLDaLINRQNQELETERRRIQEIFTAYDTYKTARDREFEDLLTKGRQNQANVDAAVASLKETEDK 340
                 33333303466777777777777777777777777777777777777777777777777777766665 PP

>> Lebercilin  Ciliary protein causing Leber congenital amaurosis disease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3  22.7     0.033        59       4     107 ..     117     220 ..     115     262 .. 0.69
   2 ?    6.3  12.1    0.0038       6.9      87     187 ..     240     342 ..     231     344 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.033
  Lebercilin   4 RvlsarllkikeLqnelaelqskleelrkEnklLkrlqkrqekaLskyedteaeLpqllarhneEvrvlrerlRksqekerelekklkekeaellrlkd 102
                 Rv+   +++i +L+ el+  +s+ ee ++ n++Lk++    +++L++ e++++     +ar +  ++ lr+++ + + +  ++e ++ + ++ + + +d
  EEA18636.1 117 RVIHNLQEEIARLTRELSLYRSRAEEAQHINETLKEQIINISERLRNSEQSNETNLASIARKDRKIEDLRAEVQNEKSRRLRAEAETAKVNQLMSEEQD 215
                 8889999******************************************99887777788888888888888877777777666666666655555554 PP

  Lebercilin 103 klkkl 107
                 +  + 
  EEA18636.1 216 EFHRK 220
                 43322 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0038
  Lebercilin  87 ekklkekeaellrlkdklkklkkLsedknLaeree..LqkkLeeleakleekeekikeLerkleleeksfrrqlaaekkktkeaqeevkalqeeierlk 183
                 + +l+e+ +  ++ k   ++l +L ++ +L++re+  L   +++ +++le+++++i+e     +  + +++r+ +    k ++ q++v+a+ + +++ +
  EEA18636.1 240 KTSLRERSDMQRKFKGIRDELASLRDQAELKDREQerLDALINRQNQELETERRRIQEIFTAYDTYKTARDREFEDLLTKGRQNQANVDAAVASLKETE 338
                 456778888888888888888999999999877642277889999999999999999999999999999999999999999999999999999999999 PP

  Lebercilin 184 qklk 187
                 +k+k
  EEA18636.1 339 DKMK 342
                 8876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (355 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2250  (0.125495); expected 358.6 (0.02)
Passed bias filter:                      467  (0.0260472); expected 358.6 (0.02)
Passed Vit filter:                        81  (0.00451782); expected 17.9 (0.001)
Passed Fwd filter:                        41  (0.0022868); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 1.06u 0.38s 00:00:01.44 Elapsed: 00:00:00.59
# Mc/sec: 1817.76
//
Query:       EEA18637.1  [L=765]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        1.2    7.2   4.7        1.6    6.7   4.7    1.1  1  Hid1      High-temperature-induced dauer-formation protein


Domain annotation for each model (and alignments):
>> Hid1  High-temperature-induced dauer-formation protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   4.7   9.2e-05       1.6     562     708 ..     220     397 ..     217     434 .. 0.65

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 9.2e-05
        Hid1 562 lrkrkvfealrnltlesaseeiersnesarldsideeeeenssessrieesrsesrspslsevpelksslaitddeskaereksatessssqavs.... 656
                 lr ++++  l++ ++++ ++ + ++++  +       + ++s ++++ + +++  r + + +v+e+ +s+ +++ ++ka++   ++ s+++q  s    
  EEA18637.1 220 LRPKEYYSILASENTDRVTQWVDQNKK--SDSTTPPVDPQQSVPPEEYPPEQKPVRGVLKRRVRETSKSSPVKSAKAKATQ---EQASADPQPISslip 313
                 789999999**********99999999..3333333444455555556665555555555555555555555554444444...344444443344666 PP

        Hid1 657 ...................................qlremsekarakesaesteesrqesatskkspsgmsqsaeekftptsewles 708
                                                     + +     ++++s+ s+ esr+   +s ++p++++++++e+f+pt+++ ++
  EEA18637.1 314 wkpkpvptfhhtmaqkvspgtnsplkqttldkywtSAVG---AFEKEKSKRSKPESRESPPSSTSRPTTTTENVAESFIPTQKYANE 397
                 888888888888888888888888888887654332222...2333444445555666666777778888999*********99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (765 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       621  (0.0346366); expected 358.6 (0.02)
Passed bias filter:                      381  (0.0212505); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.80u 0.38s 00:00:01.18 Elapsed: 00:00:00.56
# Mc/sec: 4093.02
//
Query:       EEA18638.1  [L=1082]
Description: DNA repair/transcription protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
   8.7e-124  413.9  24.0   2.6e-123  412.3  15.2    3.6  4  MMS19_C    RNAPII transcription regulator C-terminal
    6.2e-94  314.4   2.6    4.9e-93  311.5   0.1    3.1  3  MMS19_N    Dos2-interacting transcription regulator of RNA-Po
  ------ inclusion threshold ------
      0.013   15.7   0.0       0.18   11.9   0.0    2.8  2  7TMR-HDED  7TM-HD extracellular
      0.021   15.2   9.2        6.3    7.3   0.1    6.2  6  HEAT_2     HEAT repeats
      0.082   12.9   3.9       0.23   11.5   0.1    3.5  3  Cnd1       non-SMC mitotic condensation complex subunit 1
       0.13   12.4   0.0         18    5.6   0.0    2.5  2  DUF1912    Domain of unknown function (DUF1912)
       0.24   10.9   2.1         18    4.8   0.1    3.6  3  CLASP_N    CLASP N terminal
        0.4   10.2   2.1        1.9    8.0   0.1    2.5  2  DegS       Sensor protein DegS
       0.56   10.6  11.5         17    6.0   0.1    6.1  7  HEAT       HEAT repeat
        2.8    8.6  16.4         25    5.5   0.3    6.4  6  HEAT_EZ    HEAT-like repeat


Domain annotation for each model (and alignments):
>> MMS19_C  RNAPII transcription regulator C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0     0.019        35      66     147 ..     115     208 ..      96     219 .. 0.76
   2 ?    1.6   0.0     0.068   1.2e+02     376     407 ..     246     278 ..     237     287 .. 0.79
   3 ?   -1.4   0.2      0.53   9.6e+02      97     184 ..     384     451 ..     297     486 .. 0.57
   4 !  412.3  15.2  1.5e-126  2.6e-123       1     423 []     525     969 ..     525     969 .. 0.97

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.019
     MMS19_C  66 stllkllekkqtdlekeellnsyydrivprlltlvvsaastss...........siltddrllevlgriinlivrslsss.kqqevleevvalf 147
                 +t+++++e+ ++ +   ++ ++ + ++v  l+++   a  +             ++++d+r+l ++ +i+n+++ + + + + +++++ v+++f
  EEA18638.1 115 ETVRAIFEHHKELQARAQSQRYQVYQLVNGLMENHRTALHDLGdesligivdlmTGEKDPRNLMLVFSILNVLMVEWDIThHVETLFDSVYNYF 208
                 5666777776644555666677788888888888555444333557888888889***********************9955578899999988 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.068
     MMS19_C 376 lPlLlqaLdlpdaevkastLetlksile.esps 407
                 +P L++ Ld ++++vk+ +L+ l + +e  + +
  EEA18638.1 246 FPALIDKLDSTSNNVKRDSLNALVACIEsYDTN 278
                 899999999999999999999999999843344 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.53
     MMS19_C  97 ltlvvsaastsssiltddrllevlgriinlivrslsss.kqqevleevvalfltgdask.......kfeplsesasesqkqliilftailaalrke 184
                 +t                              ++ +s  kq ++le +v+l+    +          ++ +++  ++ q+q + +f+++l +  ke
  EEA18638.1 384 FTI----------------------------YQEADSIaKQRAFLETYVTLLDAAIDLYgtwadkgFTQQFENPLTSFQDQFTEVFSQALMGSAKE 451
                 333............................33333322333333333333332222223333333333333333333333344555555544444 PP

  == domain 4  score: 412.3 bits;  conditional E-value: 1.5e-126
     MMS19_C   1 pallatLpdsaseasasayervLeaLaelssekqlfetlvirllnkldlvlksnessaayahailstllkllekkqtdlekeellnsyydrivprlltl 99 
                 pa++atLpd++++++ + y ++L++La++s ++++fetlv+rllnkldl+l++++s+++ya++il t+++++ekk  d +++ +l+syydriv+ l ++
  EEA18638.1 525 PAFMATLPDQDDGTDMK-YITTLDTLAQISAQRNIFETLVRRLLNKLDLLLQADNSHPRYARIILLTIIHAMEKKPDDAIQTLSLDSYYDRIVVGLSKR 622
                 89************999.********************************************************************************* PP

     MMS19_C 100 vvsaastss.siltddrllevlgriinlivrslssskqqevleevvalfltgdaskkfeplsesasesqkqliilftailaalrkevkl........pd 189
                 ++ a++++s +il+d ++l++lgr++ liv s+s++kq+ev+e++++lf+++++ +k++p+s++++++qk+++il+t++la+l+k+++          d
  EEA18638.1 623 AALASTNDSsKILRDVSVLDTLGRLCALIVHSISREKQDEVAENIYTLFTSQSDAFKPVPFSQTNNQNQKRTMILSTYLLAGLPKDTTKlpytttnpAD 721
                 8888887778****************************************************************************7666****99999 PP

     MMS19_C 190 lsellnellellaseaespflrlaylrllallvNKflkdedlselldellesieeslieaedsqerkaaleiliwitKALvlRghplatelldkLlelL 288
                 + +ll++l++ la+++++p  +l++ r++al++NKfl+ + l+ + d + +s+ +s+++  +    ++ +++l+wi+KAL lR++p+++ +l++Ll+lL
  EEA18638.1 722 TITLLKDLVQ-LAESTDEPAVQLSIHRQIALFINKFLPASALPLAADFFTQSFPQSSES-INTGILPNRIKTLFWISKALALRLAPSTSSILSQLLTLL 818
                 99999*****.9999*****************************************999.89999********************************** PP

     MMS19_C 289 s.edaelgqlvakafgvlvsddevvlskknhanirlLykQrfFstvlpklvegfks.......sdsetkenyLvALshllkhvPkslllpeLptLlPlL 379
                 s +d ++++++ak+f++++s+d+v ls++n+anirlL kQr+F  v+p+++++f++       + s++k+ yL+ALs++l+++P+sl+lpeLp+LlPlL
  EEA18638.1 819 SsTDRATSETAAKGFSLILSPDDV-LSTQNGANIRLLSKQRVFGIVVPMISSQFRAlptpsteDASHIKPSYLTALSGILTSIPPSLVLPELPSLLPLL 916
                 ************************.*************************************999********************************** PP

     MMS19_C 380 lqaLdlpdae.....vkastLetlksile..espslvse..hlssLvprLLkl 423
                 lq+Ldl++++     vk++tL+t++++++    +s++++  h+s+Lv+rLLk+
  EEA18638.1 917 LQSLDLTSDAatsipVKQATLHTFSVLIRdnGGASIIDQtgHVSELVKRLLKT 969
                 ********999******************6444******************96 PP

>> MMS19_N  Dos2-interacting transcription regulator of RNA-Pol-II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  311.5   0.1   2.7e-96   4.9e-93       1     261 []      40     297 ..      40     297 .. 0.99
   2 ?    0.8   0.1      0.17   3.1e+02      38      89 ..     436     488 ..     425     546 .. 0.57
   3 ?   -2.0   0.0       1.2   2.1e+03     207     245 ..     910     953 ..     878     968 .. 0.75

  Alignments for each domain:
  == domain 1  score: 311.5 bits;  conditional E-value: 2.7e-96
     MMS19_N   1 veaLgeyLtseddkvRakavslLaevlsrlpkkklseeevevLvqFflsrledfavlkealkgllaLlrlkkfsaeeavevlralfeevh.vqslaqad 98 
                 v++Lgey++ +d  +R kavs+La+v++++++k+l++++++vL++Ff++r+ed  ++     gl +L+rl++f+ + a+e +ra+fe+ + +q+ aq++
  EEA18638.1  40 VQSLGEYINYDDAIIRGKAVSYLAAVVKAFSSKFLTRQQIQVLTTFFCDRIEDGGAV----TGLDTLQRLERFTRDFAQETVRAIFEHHKeLQARAQSQ 134
                 89*****************************99********************9886....9************************99999******** PP

     MMS19_N  99 RklvyelldallekhrealkelgedflegfvelvdgEkDPrnLllvfellkvllrefdlsalaeelFdvvscYFPitFrpppndpygitredLkaaLre 197
                 R++vy+l++ l+e+hr+al++lg++ l g+v+l++gEkDPrnL+lvf++l+vl+ e+d+++++e+lFd+v++YFPitF+pppndpygit++dLk++L++
  EEA18638.1 135 RYQVYQLVNGLMENHRTALHDLGDESLIGIVDLMTGEKDPRNLMLVFSILNVLMVEWDITHHVETLFDSVYNYFPITFKPPPNDPYGITAQDLKDRLQA 233
                 *******************99****************************************************************************** PP

     MMS19_N 198 claasplfaplalplllekLdstsvsakldaLqtlaacveaygaeavaehlralwsalkkeiln 261
                 c+a+++lfap+a+p+l++kLdsts ++k+d+L++l+ac+e+y++++v++++ ++w+a+k+eiln
  EEA18638.1 234 CIASNSLFAPHAFPALIDKLDSTSNNVKRDSLNALVACIESYDTNTVSRYSIQVWDAVKFEILN 297
                 **************************************************************96 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.17
     MMS19_N  38 eevevLvqFflsrle.dfavlkealkgllaLlrlkkfsaeeavevlralfeev 89 
                 + +ev++q ++   + + +  ++al+gll+L++l++f +++ + ++ ++++e+
  EEA18638.1 436 QFTEVFSQALMGSAKeEISFRQTALQGLLRLSTLRNFFQDNEIGLFVQYLDEI 488
                 55566666666666656666778888888888888877666555444433222 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 1.2
     MMS19_N 207 plalplllekLdstsvs.....akldaLqtlaacveaygaeava 245
                 p +lplll++Ld ts       +k+ +L+t    ++  g +++ 
  EEA18638.1 910 PSLLPLLLQSLDLTSDAatsipVKQATLHTFSVLIRDNGGASII 953
                 56889999999765444334448889998888777776666655 PP

>> 7TMR-HDED  7TM-HD extracellular
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0    0.0001      0.18      34     179 ..     116     398 ..     103     401 .. 0.68
   2 ?   -0.7   0.9      0.72   1.3e+03      40      59 ..     654     673 ..     427     831 .. 0.67

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.0001
   7TMR-HDED  34 svppvydldpevteqvrqelenlleeleelra................................................................... 65 
                  v+ ++++ +e  ++++++  ++ + ++ l +                                                                   
  EEA18638.1 116 TVRAIFEHHKELQARAQSQRYQVYQLVNGLMEnhrtalhdlgdesligivdlmtgekdprnlmlvfsilnvlmvewdithhvetlfdsvynyfpitfkp 214
                 555555555555555555555555554444445555555666666666666677777777777777777777777777777777777777788888888 PP

   7TMR-HDED  66 ..........................tseenlselieqlkqarekyaqa....................gaelsdeelrallelsdeeleelqqgieqi 118
                                            +++++++li++l+ + +  +++                    + ++ d++  ++l+ ++++l+e++ +  ++
  EEA18638.1 215 ppndpygitaqdlkdrlqaciasnslFAPHAFPALIDKLDSTSNNVKRDslnalvaciesydtntvsrySIQVWDAVKFEILNVQEDFLSEMSLSMLKV 313
                 888888888888888888888888887788888888888888777777677777554444444455544222233333355555556666666666666 PP

   7TMR-HDED 119 lerilsq...giped...........eearekvke.qlqaa.........lseearelatkllssvlkpNlvyDeeaTekrreea 179
                 + + ls+   ++++d           +e +e+++e q+++a         +s+++ +++t +++sv+ p +++ +ea   ++++a
  EEA18638.1 314 IVKRLSEhtvQVTQDmplahflkpiiTECNEQLREpQAKQAkpareiirnVSSASIPAFTLVIQSVVAPLFTIYQEADSIAKQRA 398
                 555555555556666999****999977778888877766666677777788999999999***********9999988888877 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.72
   7TMR-HDED  40 dldpevteqvrqelenllee 59 
                 +++ e  ++v +++ +l+++
  EEA18638.1 654 SISREKQDEVAENIYTLFTS 673
                 33444444444444444444 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0      0.89   1.6e+03      31      58 ..      38      65 ..       9      85 .. 0.65
   2 ?    3.8   0.0     0.043        78      13      58 ..     226     271 ..     222     292 .. 0.85
   3 ?   -0.7   0.1       1.1   1.9e+03      33      71 ..     524     566 ..     497     607 .. 0.54
   4 ?   -0.2   0.0      0.73   1.3e+03      33      51 ..     726     745 ..     719     771 .. 0.59
   5 ?    2.0   0.0      0.15   2.7e+02      29      58 ..     807     836 ..     792     845 .. 0.73
   6 ?    7.3   0.1    0.0035       6.3      33      54 ..    1044    1065 ..    1039    1077 .. 0.80

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.89
      HEAT_2 31 ealpaLvellededpavRraaaeaLgai 58
                ++++ L e+++ +d+ +R  a+ +L+a+
  EEA18638.1 38 DVVQSLGEYINYDDAIIRGKAVSYLAAV 65
                5677777778888888888888888765 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.043
      HEAT_2  13 dpevrraairaLgrignpealpaLvellededpavRraaaeaLgai 58 
                 d + r +a++a  ++  p a+paL++ l++++ +v r   +aL+a+
  EEA18638.1 226 DLKDRLQACIASNSLFAPHAFPALIDKLDSTSNNVKRDSLNALVAC 271
                 5577889999999888899******************999999876 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 1.1
      HEAT_2  33 lpaLvellededpavRraaaeaL...gaigdpeal.paLkell 71 
                 lpa+   l d+d  + +  +++L   ++i  ++++ + L ++l
  EEA18638.1 524 LPAFMATLPDQDDGTDMKYITTLdtlAQISAQRNIfETLVRRL 566
                 5555555555555555544443311134443333224444443 PP

  == domain 4  score: -0.2 bits;  conditional E-value: 0.73
      HEAT_2  33 lpaLvelleded.pavRraa 51 
                 l+ Lv+l+e++d pav+  +
  EEA18638.1 726 LKDLVQLAESTDePAVQLSI 745
                 45555555333225555433 PP

  == domain 5  score: 2.0 bits;  conditional E-value: 0.15
      HEAT_2  29 npealpaLvellededpavRraaaeaLgai 58 
                 + ++l  L+ ll+++d+a+ ++aa+  + i
  EEA18638.1 807 TSSILSQLLTLLSSTDRATSETAAKGFSLI 836
                 3477999****************9976655 PP

  == domain 6  score: 7.3 bits;  conditional E-value: 0.0035
      HEAT_2   33 lpaLvellededpavRraaaea 54  
                  l+ L+ +l+d++++vR+aa++a
  EEA18638.1 1044 LRELLTILDDPKRDVRKAAVDA 1065
                  6678888899999999999987 PP

>> Cnd1  non-SMC mitotic condensation complex subunit 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       4.6   8.2e+03      75     113 ..     304     344 ..     293     347 .. 0.60
   2 ?   11.5   0.1   0.00013      0.23      37     146 ..     455     571 ..     435     588 .. 0.82
   3 ?   -0.0   0.1      0.45   8.1e+02      24      42 ..    1045    1063 ..    1036    1066 .. 0.61

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 4.6
        Cnd1  75 vanalaalteiseksenaiynllpdi..isklsdalnecse 113
                 ++++l++l+ i ++ ++ ++++++d+  ++ l+  ++ec+e
  EEA18638.1 304 SEMSLSMLKVIVKRLSEHTVQVTQDMplAHFLKPIITECNE 344
                 55666777777777445555555553325566666677776 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 0.00013
        Cnd1  37 VRktaaivvakL.ilndmvkekg...flselaklleDen....prVvanalaalteiseksenaiynllpdiisklsdalnecsewgqitilefLlsyi 127
                  R+ta+ ++++L  l++++++++   f++ l ++l  e+        + a++al e+s+ ++n+i++++   +   + ++++ +  + it l++L++  
  EEA18638.1 455 FRQTALQGLLRLsTLRNFFQDNEiglFVQYLDEILLKEEvvgsGVLKKDAVSALAELSRYKSNIIMEITLPAFMATLPDQDDGTDMKYITTLDTLAQIS 553
                 5899999999999888888877767888888888744442342345678***********99*****997766666668899***************** PP

        Cnd1 128 pkdkqeaeslveklcprlq 146
                 ++ +   e+lv +l ++l 
  EEA18638.1 554 AQRNI-FETLVRRLLNKLD 571
                 99999.9999999999875 PP

  == domain 3  score: -0.0 bits;  conditional E-value: 0.45
        Cnd1   24 epLrkrLkDedpyVRktaa 42  
                   +L + L D++  VRk a+
  EEA18638.1 1045 RELLTILDDPKRDVRKAAV 1063
                  4455556666666666664 PP

>> DUF1912  Domain of unknown function (DUF1912)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0      0.01        18      23      77 ..     111     159 ..     107     164 .. 0.83
   2 ?    3.8   0.0     0.036        64      30      69 ..     653     692 ..     644     699 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.01
                 HHHHHHHHHH------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHT--TTS---- CS
     DUF1912  23 elaleaskkvleedkderakdaliryeskldaykfllgkfenykagkgfhdlPde 77 
                 ++a e+ + ++e  k+ +a+  + ry      y+++ g +en+++  ++hdl de
  EEA18638.1 111 DFAQETVRAIFEHHKELQARAQSQRY----QVYQLVNGLMENHRT--ALHDLGDE 159
                 67888899999999999998888777....58**********996..69999986 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.036
                 HHH------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHT- CS
     DUF1912  30 kkvleedkderakdaliryeskldaykfllgkfenykagk 69 
                 + + +e +de a++ +  + s+ da+k +    +n +++k
  EEA18638.1 653 HSISREKQDEVAENIYTLFTSQSDAFKPVPFSQTNNQNQK 692
                 56899*********************98877777777776 PP

>> CLASP_N  CLASP N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.1      0.46   8.2e+02      93     170 ..     243     327 ..     227     348 .. 0.54
   2 ?    2.8   0.0     0.041        73     125     185 ..     562     619 ..     516     621 .. 0.83
   3 ?    4.8   0.1    0.0098        18      67     122 ..     782     837 ..     770     844 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.46
     CLASP_N  93 eillptLlkllgdtKkiisqnanqalaallsnas..fspri.lqvlsv....alqdKnvqpReysaiwLkilltrfeshksklea 170
                  + +p L++ l +t + +   + +al a +++      +r  +qv  +    +l+    ++ e+s+  Lk++++r ++h+ ++++
  EEA18638.1 243 PHAFPALIDKLDSTSNNVKRDSLNALVACIESYDtnTVSRYsIQVWDAvkfeILNVQEDFLSEMSLSMLKVIVKRLSEHTVQVTQ 327
                 5667777777777777777777777777777655112233323332221111222223334555566666666666555544444 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.041
     CLASP_N 125 asfsprilqvlsvalqdKnvqpReysaiwLkilltrfeshkskleasllldliekslkkgl 185
                 +    r+l+ l ++lq  n  pR   +i+L+i++   ++   +++  + ld++ + ++ gl
  EEA18638.1 562 L--VRRLLNKLDLLLQADNSHPRYARIILLTIIHAMEKKPDDAIQTLS-LDSYYDRIVVGL 619
                 3..48999**********************999999885555555544.788877777766 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.0098
     CLASP_N  67 ttlsstgchllkelaiqlkeqldpmveillptLlkllgdtKkiisqnanqalaall 122
                 t +  + +++l  +++ l  +l+p+  ++l+ Ll+ll++t   +s++a+  ++ +l
  EEA18638.1 782 TGILPNRIKTLFWISKALALRLAPSTSSILSQLLTLLSSTDRATSETAAKGFSLIL 837
                 555556666677778888899***************************99888776 PP

>> DegS  Sensor protein DegS
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   0.1     0.001       1.9       5      54 ..       5      54 ..       2      79 .. 0.83
   2 ?    0.5   0.4      0.21   3.7e+02      71     102 ..     109     140 ..     100     144 .. 0.77

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.001
        DegS  5 kktietiekskeeifeIaEsarkeverlkkeleelkeevsevikevdkle 54
                ++ + t+++ k   + IaE++ ++ve+ ++ l ++ + + e+i+  d++ 
  EEA18638.1  5 QTFMLTVDRDKPAAIAIAEQTAQDVENKQTTLLDVVQSLGEYINYDDAII 54
                66788999***********************************9988764 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.21
        DegS  71 FkkyseeeikeaYeeakelqvelallrekEkq 102
                  +++ +e++++ +e+ kelq++ + +r +  q
  EEA18638.1 109 TRDFAQETVRAIFEHHKELQARAQSQRYQVYQ 140
                 3457899*************999998876555 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.0        10   1.8e+04      11      29 ..      49      67 ..      45      68 .. 0.78
   2 ?    0.1   0.0      0.73   1.3e+03       2      29 ..     246     273 ..     245     275 .. 0.87
   3 ?   -3.4   0.0       9.9   1.8e+04      16      27 ..     455     466 ..     451     468 .. 0.78
   4 ?    1.2   0.0      0.33   5.9e+02       1      27 [.     810     836 ..     810     838 .. 0.88
   5 ?   -1.1   0.0       1.8   3.3e+03       1      26 [.     912     942 ..     912     945 .. 0.60
   6 ?    4.7   0.2     0.024        43      13      25 ..     983     995 ..     982     997 .. 0.84
   7 ?    6.0   0.1    0.0095        17       2      23 ..    1044    1065 ..    1043    1065 .. 0.87

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 10
                -SSHHHHHHHHHHHHHHHH CS
        HEAT 11 DpspeVReaAakaLgalae 29
                 +++ +R  A+  L+a+++
  EEA18638.1 49 YDDAIIRGKAVSYLAAVVK 67
                5677789999999998876 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.73
                 HHHHHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   2 lPlllkllsDpspeVReaAakaLgalae 29 
                 +P+l+  l ++s +V + +++aL+a +e
  EEA18638.1 246 FPALIDKLDSTSNNVKRDSLNALVACIE 273
                 58999999*******9999999998776 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 9.9
                 HHHHHHHHHHHH CS
        HEAT  16 VReaAakaLgal 27 
                  R++A++ L +l
  EEA18638.1 455 FRQTALQGLLRL 466
                 5999*9999877 PP

  == domain 4  score: 1.2 bits;  conditional E-value: 0.33
                 HHHHHHHHHT-SSHHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgal 27 
                 +l  ll+lls+++    e+Aak +  +
  EEA18638.1 810 ILSQLLTLLSSTDRATSETAAKGFSLI 836
                 7899***********999999998766 PP

  == domain 5  score: -1.1 bits;  conditional E-value: 1.8
                 HHHHHHHHHT-......SSHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsD......pspeVReaAakaLga 26 
                 llPlll+ l D      +s  V +a++ ++  
  EEA18638.1 912 LLPLLLQSL-DltsdaaTSIPVKQATLHTFSV 942
                 789976655.3333466666777777666665 PP

  == domain 6  score: 4.7 bits;  conditional E-value: 0.024
                 SHHHHHHHHHHHH CS
        HEAT  13 speVReaAakaLg 25 
                 ++ VReaA+++L 
  EEA18638.1 983 AATVREAALRCLY 995
                 578********96 PP

  == domain 7  score: 6.0 bits;  conditional E-value: 0.0095
                  HHHHHHHHT-SSHHHHHHHHHH CS
        HEAT    2 lPlllkllsDpspeVReaAaka 23  
                  l  ll+ l Dp  +VR+aA+ a
  EEA18638.1 1044 LRELLTILDDPKRDVRKAAVDA 1065
                  56689999***********976 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0      0.82   1.5e+03      24      52 ..     240     268 ..     232     269 .. 0.82
   2 ?   -1.6   0.0       2.4   4.2e+03      22      47 ..     559     584 ..     552     590 .. 0.83
   3 ?    0.8   0.1      0.41   7.3e+02      22      50 ..     803     831 ..     798     836 .. 0.79
   4 ?    5.5   0.3     0.014        25      16      54 ..     899     942 ..     890     943 .. 0.75
   5 ?    2.1   0.2      0.17     3e+02      42      53 ..     983     995 ..     953     997 .. 0.67
   6 ?    5.2   0.1     0.017        30      29      51 ..    1043    1065 ..    1032    1065 .. 0.87

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.82
     HEAT_EZ  24 plvpeilpaLlalLnddsdeVRaaAagaL 52 
                 ++ p + paL+  L + s +V+  ++ aL
  EEA18638.1 240 LFAPHAFPALIDKLDSTSNNVKRDSLNAL 268
                 56778899999999999999988777776 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 2.4
     HEAT_EZ  22 lqplvpeilpaLlalLnddsdeVRaa 47 
                  ++lv ++l  L  lL+ d+++ R+a
  EEA18638.1 559 FETLVRRLLNKLDLLLQADNSHPRYA 584
                 57889999999999999999999987 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.41
     HEAT_EZ  22 lqplvpeilpaLlalLnddsdeVRaaAag 50 
                 l+p  + il +Ll lL++ + ++ ++Aa 
  EEA18638.1 803 LAPSTSSILSQLLTLLSSTDRATSETAAK 831
                 6677889*********9988888777775 PP

  == domain 4  score: 5.5 bits;  conditional E-value: 0.014
     HEAT_EZ  16 ggepellqplvpeilpaLlalL.nddsd....eVRaaAagaLgn 54 
                 +  p l+ p++p +lp+Ll+ L  ++++    +V++a++++++ 
  EEA18638.1 899 SIPPSLVLPELPSLLPLLLQSLdLTSDAatsiPVKQATLHTFSV 942
                 45699999***********9997666665655558888888875 PP

  == domain 5  score: 2.1 bits;  conditional E-value: 0.17
     HEAT_EZ  42 d.eVRaaAagaLg 53 
                 + +VR+aA+++L 
  EEA18638.1 983 AaTVREAALRCLY 995
                 5478999999986 PP

  == domain 6  score: 5.2 bits;  conditional E-value: 0.017
     HEAT_EZ   29 ilpaLlalLnddsdeVRaaAaga 51  
                  +l++Ll  L d++ +VR+aA+ a
  EEA18638.1 1043 VLRELLTILDDPKRDVRKAAVDA 1065
                  67889999999999******976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1082 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       812  (0.0452898); expected 358.6 (0.02)
Passed bias filter:                      631  (0.0351944); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 1.02u 0.40s 00:00:01.42 Elapsed: 00:00:00.59
# Mc/sec: 5503.76
//
Query:       EEA18639.1  [L=255]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.8e-05   24.4   0.0    4.2e-05   23.8   0.0    1.3  1  Fasciclin  Fasciclin domain


Domain annotation for each model (and alignments):
>> Fasciclin  Fasciclin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.0   2.4e-09   4.2e-05      14     123 ..     129     249 ..     115     253 .. 0.79

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 2.4e-09
                 TCCCCCTCSSSSEEEEEE-HHHHCCC.......HHHHHHHHHT.......CHHHHHHHHHTTEEESSS-HHHHHHHHEEEECCTTSSEEEEEEEGGTTE CS
   Fasciclin  14 glaeeLnkkdgglTvFaPtneAfakl.......ppellaklln.......dkkklkeiLkyHvvpetvsssalkkasetlatllegaklrvniekgngt 98 
                  +a+ Ln+k ++ Tv+aP n+A++ l       p++ +++ ++       +k+ +++ L+ +v +  v  s ++++ e+++t + g k++  +e  ++t
  EEA18639.1 129 PIASRLNDKSQNTTVLAPLNSAINSLprkpwedPEDYERFGKAqaykgdeGKDRAQRNLQRFVEAHLVPVSPWREG-EEVET-VGGGKVKWVKE--GDT 223
                 5788999999*************6666666664333333322255556679999999999999999999*******.*****.*******9999..99* PP

                 EEETT.EEEEEEEEEEESSEEEEEES CS
   Fasciclin  99 vtvng.karvvrsdieatngvihvid 123
                 v+++    +v ++  e +ng + v+ 
  EEA18639.1 224 VFIEPgHIEVDSTASEVSNGNVWVLK 249
                 ****9999999999999999998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (255 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       493  (0.0274974); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.34s 00:00:00.97 Elapsed: 00:00:00.55
# Mc/sec: 1392.47
//
Query:       EEA18640.1  [L=264]
Description: DUF850 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.5e-53  179.5   0.5    5.9e-53  179.1   0.5    1.1  1  EMC3_TMCO1  Integral membrane protein EMC3/TMCO1-like


Domain annotation for each model (and alignments):
>> EMC3_TMCO1  Integral membrane protein EMC3/TMCO1-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  179.1   0.5   3.3e-57   5.9e-53       2     169 ..      10     203 ..       9     204 .. 0.97

  Alignments for each domain:
  == domain 1  score: 179.1 bits;  conditional E-value: 3.3e-57
  EMC3_TMCO1   2 lvldplirdwvllPivivillvgiltgllsellqkllidkkkmekeqkrekelqkrarelqkngd.klklkklekrqeelmedqsem............ 87 
                 +v dp++ +w+l+Pi+iv++l+gil+++++ l+++ +  k   +  + re+  + +  +l++n    l ++ +++r+e+l+ +  ++            
  EEA18640.1  10 IVRDPALFYWILIPITIVMILTGILRHYATVLMNSPP--KPASTLLESRERLSLIHGVNLRNNACaVLTPEGFASRKEYLISAYNNGaflkdpenrgqp 106
                 899********************************99..8889999****************886599******************************* PP

  EMC3_TMCO1  88 .............mmdqmkpmivtmipqiliffwlnsffsgfvvaklpfpltgrfksllqrgl..esldvrfvssiswYflcsfglsqiirklLgea 169
                              mm +mk+++++mipq+li++w+n+ffsgfv++klpfplt+rfks+lq+g+   +ldvr+vss+swYfl+++gl++i+  +Lg +
  EEA18640.1 107 panpmsdpaamegMMGMMKGNMMMMIPQTLIMSWINAFFSGFVILKLPFPLTIRFKSMLQSGVatRDLDVRWVSSLSWYFLNLMGLQSIFGFILGAD 203
                 **********************************************************************************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (264 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       575  (0.0320709); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.33s 00:00:00.94 Elapsed: 00:00:00.54
# Mc/sec: 1472.74
//
Query:       EEA18641.1  [L=213]
Description: signal peptidase complex component, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.9e-48  163.3   0.1    4.6e-48  163.1   0.1    1.1  1  SPC25     Microsomal signal peptidase 25 kDa subunit (SPC25)
  ------ inclusion threshold ------
      0.056   13.5   0.0        0.1   12.6   0.0    1.3  1  SCAB-Ig   Ig domain of plant-specific actin-binding protein


Domain annotation for each model (and alignments):
>> SPC25  Microsomal signal peptidase 25 kDa subunit (SPC25)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  163.1   0.1   5.2e-52   4.6e-48       1     161 [.      16     175 ..      16     176 .. 0.97

  Alignments for each domain:
  == domain 1  score: 163.1 bits;  conditional E-value: 5.2e-52
       SPC25   1 elKntlDdalkeyltdl....gfkeshtltdvrLalGylavaiaavaflydykveFeesk.pvlaiavvlYfilsgiltlystfvekntifvgkrktgs 94 
                 +lK+t+Dda+  yl++l    +f+ ++  t++r++lGy+avaia+v+f++d  +++e++   ++ +av +Yf+l+++l+++++ ve++++f+g rk+g+
  EEA18641.1  16 DLKSTTDDAFTPYLCTLpqpyTFTRDNSKTTIRFILGYTAVAIAGVTFYLDRQLGWEATEaVWVKWAVGVYFLLNTLLQYWIWAVEAGEVFRGVRKDGN 114
                 79**************998888*************************************869************************************7 PP

       SPC25  95 kriekitissslkklsptytltvsykdksnkgkslkakeleksvgewFdedGylveeefeqwlakll 161
                      iti+s +kk+sp+y+++v+y   + kgk l++ke+e +++ wF ++G+++ e+f++wlak++
  EEA18641.1 115 ----AITIQSLTKKHSPIYKIKVQY--ATPKGKILQRKEIESPFTAWFAANGTFHPEPFRAWLAKEI 175
                 ....7********************..777899*******************************987 PP

>> SCAB-Ig  Ig domain of plant-specific actin-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   1.1e-05       0.1       5      90 ..     108     199 ..     105     203 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.1e-05
     SCAB-Ig   5 GsetLGsllriqpssdeavdlskcsiqWyrvssegskkelisG......atksvyaPePfdvGrilqadivlngekvivttagpidpaagLg 90 
                 G    G  ++iq+ +++++ + k+++q+   + +  ++  i        a + ++ PePf +    ++d+  +++k +++ +g +    g++
  EEA18641.1 108 GVRKDGNAITIQSLTKKHSPIYKIKVQYATPKGKILQRKEIESpftawfAANGTFHPEPFRAWLAKEIDVLGEAQKETLKKTGDVSGHVGVE 199
                 66677999********************9999998777766542333446777889****************************99888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (213 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       344  (0.0191868); expected 358.6 (0.02)
Passed bias filter:                      257  (0.0143343); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.46
# Mc/sec: 1390.76
//
Query:       EEA18642.1  [L=322]
Description: methylenetetrahydrofolate dehydrogenase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.6e-26   92.2   0.0    3.8e-26   91.6   0.0    1.3  1  THF_DHG_CYH    Tetrahydrofolate dehydrogenase/cyclohydrolase,
      1e-12   47.6   0.3    2.3e-09   36.8   0.0    2.6  2  THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase,


Domain annotation for each model (and alignments):
>> THF_DHG_CYH  Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.6   0.0   4.2e-30   3.8e-26       4     116 .]      13     118 ..      10     118 .. 0.90

  Alignments for each domain:
  == domain 1  score: 91.6 bits;  conditional E-value: 4.2e-30
                  HHHHHHHHHHHHHHHHHHHHHHT---EEEEEEES--HHHHHHHHHHHHHHHHTT-EEEEEEE-TT--HHHHHHHHHHHHH-TT--EEEE-SS-STTS- CS
  THF_DHG_CYH   4 GkalakeireelkeeveklkekgvkpkLavilvgddpasevYvrnkkkaceevGieseliklpedvseeellklieelneddsvdGilvqlPlpkhid 101
                  +k++a+ + +e+++ +++l +   kp+L+++l+++dpa+++Y+++++k+c+e G++++ ++++    +ee+ ++i ++n+dd+vdGi+v++P+ ++ +
   EEA18642.1  13 AKNIANGLLQEVHDGLKTLGR---KPHLVGFLANSDPAARMYADWTEKTCHENGFQYTRRDVD----KEEIEEAILAANADDDVDGIIVYYPIFNNRQ 103
                  678888888888888887765...9**********************************9995....5778889*******************99989 PP

                  HHHHHCCS-GGGBTT CS
  THF_DHG_CYH 102 ekaileaispeKDVD 116
                  +++++++++++KDV+
   EEA18642.1 104 DQYLQQIVDVSKDVE 118
                  **************8 PP

>> THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.8   0.0   2.6e-13   2.3e-09      12      68 ..     150     215 ..     143     224 .. 0.82
   2 !    8.2   0.0   0.00015       1.4     124     158 ..     285     316 ..     238     318 .. 0.72

  Alignments for each domain:
  == domain 1  score: 36.8 bits;  conditional E-value: 2.6e-13
                    --SS--HHHHHHHHHHH.........HCT---TT-EEEEE---TTTHHHHHHHHHCTT-EEEEE-T CS
  THF_DHG_CYH_C  12 eeallpctpkgvvellk.........etgielegkkvvvvGrsnivgkplallLleknatVtvchs 68 
                    ++ +lpctp ++v++l+         ++g  l+g++++vv+rs++vg+pla+lL++++a V  ++ 
     EEA18642.1 150 QKSILPCTPLAIVKILEylrvyntilHYGNRLHGHTICVVNRSEVVGRPLAALLANDGACVYSVDI 215
                    6789***********9833333333345667*****************************988765 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.00015
                    HHHCTTSSEE--TTTSCHHHHHHHHHHHHHHHHHC CS
  THF_DHG_CYH_C 124 eevkevasaitPvpgGVGpmTvamllkntleaakr 158
                     evke+as++ P   ++G++T+++ll+n+l+ +++
     EEA18642.1 285 PEVKEKASIYVP---SIGKVTIVVLLRNLLRIVQN 316
                    589999999998...68999**********98876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (322 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       529  (0.0295053); expected 358.6 (0.02)
Passed bias filter:                      480  (0.0267723); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.30s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2117.25
//
Query:       EEA18643.1  [L=555]
Description: mitochondrial F1 ATPase subunit alpha, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.7e-72  242.9   0.0      4e-72  242.3   0.0    1.3  1  ATP-synt_ab    ATP synthase alpha/beta family, nucleotide-bin
    2.2e-49  167.0   0.7    3.8e-49  166.2   0.7    1.4  1  ATP-synt_ab_C  ATP synthase alpha/beta chain, C terminal doma
    2.7e-15   56.6   3.4    7.1e-15   55.3   3.4    1.7  1  ATP-synt_ab_N  ATP synthase alpha/beta family, beta-barrel do


Domain annotation for each model (and alignments):
>> ATP-synt_ab  ATP synthase alpha/beta family, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  242.3   0.0   6.6e-76     4e-72       1     213 []     195     418 ..     195     418 .. 0.97

  Alignments for each domain:
  == domain 1  score: 242.3 bits;  conditional E-value: 6.6e-76
                  SSHHHHHHS-EBTT-EEEEEESTTSSHHHHH.HHHHHHSSTS.......S.EEEEEEESEEHHHHHHHHHHCHHSSGGGGEEEEEEETTS-HHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxx.......x.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab   1 GirvlDalfpivqGqrtlipgafgvGktvis.qslskqsnsd.......d.aiiyvgiGergnevaevleefpegtimkrtvlvantsnepvaareas 89 
                  G++ +D+++pi++Gqr+li+g++++Gkt+++ +++++q++ +       + +++yv++G+++++va+++++++e++++k++++va+t++e++ +++++
   EEA18643.1 195 GLKSVDSMVPIGRGQRELIIGDRQTGKTAVAlDAILNQKRINagsdeskKlYCVYVAVGQKRSTVAQLVKTLEENDALKYSIIVAATASEAAPLQYLA 292
                  8899**************************999999998766889999768*********************************************** PP

                  HHHHHHHHHHHHHTTSEEEEEEETHHHHHHHHHHHHHHTTTSBEGGGSBTTHHHHHHHHHTTSEEETSS..EEEEEEEEEEE-GGCSTTSHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab  90 iytgitlAEyfrdqgknvlliadslsrwaeAlreislrlgempadqgypaylgaklaslyERagkapdr..tGsvtivaavspaggDfsdpvttatlg 185
                  ++tg++++Eyfrd+g+++++++d+ls++a A+r++sl+l+++p++++yp+++++ +++l+ERa+k++d+   Gs+t++++++++ggD+s++++t++++
   EEA18643.1 293 PFTGTAMGEYFRDNGRHAVIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDKhgGGSLTALPVIETQGGDVSAYIPTNVIS 390
                  ******************************************************************6665589************************* PP

                  HSSEEEEB-HHHHHTTBSSSBCTTTEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab 186 itdgfivLdkklaqrkhfPainvlvSvS 213
                  itdg+i+L+++l+ ++++Painv+ SvS
   EEA18643.1 391 ITDGQIFLETELFYKGIRPAINVGLSVS 418
                  **************************99 PP

>> ATP-synt_ab_C  ATP synthase alpha/beta chain, C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  166.2   0.7   6.3e-53   3.8e-49       1     124 [.     425     548 ..     425     550 .. 0.99

  Alignments for each domain:
  == domain 1  score: 166.2 bits;  conditional E-value: 6.3e-53
  ATP-synt_ab_C   1 QtkamkkvagsLklelaqYrEleaFaqFgsdLDeatkkqLerGerlvelLkQkqysplsveeqviilyaatngllddipvekvkefekelleylee 96 
                    Q+kamk+vagsLkl laqYrE++aFaqFgsdLD++tk++L+rGerl+elLkQkqysp+sv+e+v +++a+ ng+ld+ipv+k++++e+++++yl++
     EEA18643.1 425 QVKAMKQVAGSLKLFLAQYREVAAFAQFGSDLDASTKQTLNRGERLTELLKQKQYSPMSVSEMVPLIFAGVNGYLDSIPVAKIEKWEEDFIAYLKS 520
                    9*********************************************************************************************** PP

  ATP-synt_ab_C  97 ekkeileeieekkklsdeleeklkeaik 124
                    +++++l++i+++++ls+ele+klk++i 
     EEA18643.1 521 SQADVLQTIDKEGQLSKELEAKLKDIIV 548
                    ************************9986 PP

>> ATP-synt_ab_N  ATP synthase alpha/beta family, beta-barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.3   3.4   1.2e-18   7.1e-15       3      69 .]      72     138 ..      71     138 .. 0.98

  Alignments for each domain:
  == domain 1  score: 55.3 bits;  conditional E-value: 1.2e-18
                    EEETTEEEEESSTSCETCTTEEEEECCETCSTEEEEEEEEEETTEEEEEESS-STTBBTTSEEEEES CS
  ATP-synt_ab_N   3 qviGpvvdvefgigrlpgiynalevelvefgtlllgvalnlgedkVrvivmgstdGlsrGteVkrTG 69 
                    +++G v++v++gi+r++g++n+ + elvef ++++g+ +nl+ ++V+v+ +gs++ +++G++V+rTG
     EEA18643.1  72 AETGRVLSVGDGIARVHGLNNVQAEELVEFASGVKGMTMNLEAGQVGVVLFGSDRLVKEGETVRRTG 138
                    579***************************************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (555 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       446  (0.0248759); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.41
# Mc/sec: 4032.27
//
Query:       EEA18644.1  [L=555]
Description: mitochondrial F1 ATPase subunit alpha, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.7e-72  242.9   0.0      4e-72  242.3   0.0    1.3  1  ATP-synt_ab    ATP synthase alpha/beta family, nucleotide-bin
    2.2e-49  167.0   0.7    3.8e-49  166.2   0.7    1.4  1  ATP-synt_ab_C  ATP synthase alpha/beta chain, C terminal doma
    2.7e-15   56.6   3.4    7.1e-15   55.3   3.4    1.7  1  ATP-synt_ab_N  ATP synthase alpha/beta family, beta-barrel do


Domain annotation for each model (and alignments):
>> ATP-synt_ab  ATP synthase alpha/beta family, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  242.3   0.0   6.6e-76     4e-72       1     213 []     195     418 ..     195     418 .. 0.97

  Alignments for each domain:
  == domain 1  score: 242.3 bits;  conditional E-value: 6.6e-76
                  SSHHHHHHS-EBTT-EEEEEESTTSSHHHHH.HHHHHHSSTS.......S.EEEEEEESEEHHHHHHHHHHCHHSSGGGGEEEEEEETTS-HHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxx.......x.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab   1 GirvlDalfpivqGqrtlipgafgvGktvis.qslskqsnsd.......d.aiiyvgiGergnevaevleefpegtimkrtvlvantsnepvaareas 89 
                  G++ +D+++pi++Gqr+li+g++++Gkt+++ +++++q++ +       + +++yv++G+++++va+++++++e++++k++++va+t++e++ +++++
   EEA18644.1 195 GLKSVDSMVPIGRGQRELIIGDRQTGKTAVAlDAILNQKRINagsdeskKlYCVYVAVGQKRSTVAQLVKTLEENDALKYSIIVAATASEAAPLQYLA 292
                  8899**************************999999998766889999768*********************************************** PP

                  HHHHHHHHHHHHHTTSEEEEEEETHHHHHHHHHHHHHHTTTSBEGGGSBTTHHHHHHHHHTTSEEETSS..EEEEEEEEEEE-GGCSTTSHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab  90 iytgitlAEyfrdqgknvlliadslsrwaeAlreislrlgempadqgypaylgaklaslyERagkapdr..tGsvtivaavspaggDfsdpvttatlg 185
                  ++tg++++Eyfrd+g+++++++d+ls++a A+r++sl+l+++p++++yp+++++ +++l+ERa+k++d+   Gs+t++++++++ggD+s++++t++++
   EEA18644.1 293 PFTGTAMGEYFRDNGRHAVIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDKhgGGSLTALPVIETQGGDVSAYIPTNVIS 390
                  ******************************************************************6665589************************* PP

                  HSSEEEEB-HHHHHTTBSSSBCTTTEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab 186 itdgfivLdkklaqrkhfPainvlvSvS 213
                  itdg+i+L+++l+ ++++Painv+ SvS
   EEA18644.1 391 ITDGQIFLETELFYKGIRPAINVGLSVS 418
                  **************************99 PP

>> ATP-synt_ab_C  ATP synthase alpha/beta chain, C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  166.2   0.7   6.3e-53   3.8e-49       1     124 [.     425     548 ..     425     550 .. 0.99

  Alignments for each domain:
  == domain 1  score: 166.2 bits;  conditional E-value: 6.3e-53
  ATP-synt_ab_C   1 QtkamkkvagsLklelaqYrEleaFaqFgsdLDeatkkqLerGerlvelLkQkqysplsveeqviilyaatngllddipvekvkefekelleylee 96 
                    Q+kamk+vagsLkl laqYrE++aFaqFgsdLD++tk++L+rGerl+elLkQkqysp+sv+e+v +++a+ ng+ld+ipv+k++++e+++++yl++
     EEA18644.1 425 QVKAMKQVAGSLKLFLAQYREVAAFAQFGSDLDASTKQTLNRGERLTELLKQKQYSPMSVSEMVPLIFAGVNGYLDSIPVAKIEKWEEDFIAYLKS 520
                    9*********************************************************************************************** PP

  ATP-synt_ab_C  97 ekkeileeieekkklsdeleeklkeaik 124
                    +++++l++i+++++ls+ele+klk++i 
     EEA18644.1 521 SQADVLQTIDKEGQLSKELEAKLKDIIV 548
                    ************************9986 PP

>> ATP-synt_ab_N  ATP synthase alpha/beta family, beta-barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.3   3.4   1.2e-18   7.1e-15       3      69 .]      72     138 ..      71     138 .. 0.98

  Alignments for each domain:
  == domain 1  score: 55.3 bits;  conditional E-value: 1.2e-18
                    EEETTEEEEESSTSCETCTTEEEEECCETCSTEEEEEEEEEETTEEEEEESS-STTBBTTSEEEEES CS
  ATP-synt_ab_N   3 qviGpvvdvefgigrlpgiynalevelvefgtlllgvalnlgedkVrvivmgstdGlsrGteVkrTG 69 
                    +++G v++v++gi+r++g++n+ + elvef ++++g+ +nl+ ++V+v+ +gs++ +++G++V+rTG
     EEA18644.1  72 AETGRVLSVGDGIARVHGLNNVQAEELVEFASGVKGMTMNLEAGQVGVVLFGSDRLVKEGETVRRTG 138
                    579***************************************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (555 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       446  (0.0248759); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 3825.57
//
Query:       EEA18645.1  [L=445]
Description: hypothetical protein PMAA_009310 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      5e-06   26.5   9.0      1e-05   25.5   9.0    1.5  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.5   9.0   5.8e-10     1e-05       1      32 [.      18      52 ..      18      60 .. 0.81

  Alignments for each domain:
  == domain 1  score: 25.5 bits;  conditional E-value: 5.8e-10
                SS-HHHHHCT---ST....SSSS-HHHHHCTHHHCC CS
     Zn_clus  1 haCdnCrkkKvKCda....kkPaCsnCkklnleCtf 32
                +aCd+Cr +K +C        P C +C++ +++Ct 
  EEA18645.1 18 TACDRCRGQKLRCPPraneADP-CNRCVRQGAQCTT 52
                69***********996443444.***********94 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (445 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       506  (0.0282224); expected 358.6 (0.02)
Passed bias filter:                      353  (0.0196888); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.45
# Mc/sec: 2987.56
//
Query:       EEA18646.1  [L=517]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-41  142.7  42.3    1.9e-38  132.3  24.3    2.0  2  MFS_1     Major Facilitator Superfamily
    1.4e-09   37.3  13.6    1.4e-09   37.3  13.6    2.6  2  Sugar_tr  Sugar (and other) transporter
  ------ inclusion threshold ------
        2.5    8.5   5.7         29    5.1   0.4    3.6  3  Wzz       Chain length determinant protein
        7.6    6.9   0.0        7.6    6.9   0.0    4.9  7  Tad       Putative Flp pilus-assembly TadE/G-like


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.3  24.3   4.3e-42   1.9e-38       3     275 ..      72     362 ..      70     364 .. 0.80
   2 !   16.5  10.0   6.8e-07     0.003      67     172 ..     394     502 ..     386     516 .. 0.80

  Alignments for each domain:
  == domain 1  score: 132.3 bits;  conditional E-value: 4.3e-42
       MFS_1   3 laaflsalarsilgpalplalaedlg.ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgag 100
                  ++fl+ala+s+++pa+p+ +  ++  ++ +++ +++++y lg+a++ l++++ls+ +Gr +v+ ++ l+f ++++++++++s+ +l+++r+++Gl+++
  EEA18646.1  72 AMTFLTALASSVIAPAVPQ-ILAEFEsANLQVAAFVVSVYILGFAAGPLVIAPLSELYGRVPVYHVCNLGFTIFSAACALSPSIRALIIFRFFSGLFGS 169
                 689***************6.557777255666889***************************************66666556666************** PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.kgtgpaplvp 198
                 + +++g   i+d+ p+e+r+++++ +s+g+ +++i+gp++gg++a  l Wr+  ++lai +++  +++l++l e++++   +++++++ k+tg++ l++
  EEA18646.1 170 CPATIGSGSITDLIPQERRASVVAAYSVGALFAPIVGPMAGGFVAYELDWRWDCWLLAISGAIISIVMLFVLKETYHTVILERKVKRLrKQTGNQLLRS 268
                 ****************************************************************99988888888888888888888885555555555 PP

       MFS_1 199 ...........awkallkdpvlw....illialllfffgfsg.....lltllplylqevlgls....glllaglllallalvgailallagrlsdrlgr 273
                             w+ + ++  ++    i++i++l+++ +++g     +++++ ++ q  +g++    g+  +g  l+l++++g     ++++ sd++ +
  EEA18646.1 269 kldtglssgayFWRNIIRPVKMLtrspIIIITSLFIA-ITYGymyllFTSFTEVF-QRYYGFTtsnvGVCFLG--LGLGSFIG---VAIFSATSDKMIK 360
                 6677888888988888888877666653333333333.44442344344444446.*******5555555555..55555555...8889999999777 PP

       MFS_1 274 rr 275
                 r+
  EEA18646.1 361 RK 362
                 65 PP

  == domain 2  score: 16.5 bits;  conditional E-value: 6.8e-07
       MFS_1  67 lglllfalglllllfa...sslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivs 161
                 +++l++ +gll+  ++     +w + +++ vl G+g+ +l+ + + ++ d f+    ++a++ ++a  s++  l pl+g  +++ +g  +   +la+v+
  EEA18646.1 394 FAVLCLPVGLLIYGWTaewGLHWiIPIIGTVLIGIGQLLLYMVLQMYLIDSFTI-YAASAVAAITAVRSIAGGLLPLFGLSIYDKFGVGWGNTLLAFVC 491
                 55555556633333532434478799****************************.********************************999999999999 PP

       MFS_1 162 llafvlfllll 172
                 l ++++ +ll+
  EEA18646.1 492 LPLVLVSVLLI 502
                 99876544444 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.3  13.6   3.2e-13   1.4e-09      48     289 ..     103     331 ..      64     364 .. 0.76
   2 ?   -3.3   9.4      0.65   2.9e+03      78     187 ..     391     500 ..     388     508 .. 0.80

  Alignments for each domain:
  == domain 1  score: 37.3 bits;  conditional E-value: 3.2e-13
                 HHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHH CS
    Sugar_tr  48 sglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqla 146
                   ++vs++++G ++G l++ +l++ +GR +++ ++++ f i ++ +a+++   s+ +li+ R+++G++  +  ++ +  i  + p++ R  +v  y ++
  EEA18646.1 103 AAFVVSVYILGFAAGPLVIAPLSELYGRVPVYHVCNLGFTIFSAACALSP---SIRALIIFRFFSGLFGSCPATIGSGSITDLIPQERRASVVAAYSVG 198
                 35789*********************************************...*******************************************999 PP

                 HHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGG.S---HHHHHHTT-HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH.....HTT CS
    Sugar_tr 147 itfGilvaaifglglnktsnadgwrillglqlvpallllilllf.lPESPrylvekgkeeeakevlaklrgeedadrelaeekdsleaeqeeekaswke 244
                   f  +v+ + g ++++  +   wr+ ++l +++  +++i++lf l E+ + +v     e+  + l+k  g+++   +l+   +s  +        w++
  EEA18646.1 199 ALFAPIVGPMAGGFVAYELD---WRWDCWLLAISGAIISIVMLFvLKET-YHTV---ILERKVKRLRKQTGNQLLRSKLDTGLSSGAYF-------WRN 283
                 99999999999999999888...**********9988888886526888.3333...34444555666677788888888888887777.......888 PP

                 HHHHSH.....HHHHHHHHHHHHHHTTHHHHHHHTTTHHHH.SS-THH CS
    Sugar_tr 245 llsskt..vrqrlligvvlqifqqltGinaimyysptifen.lglsks 289
                 +++ ++   r +++i+  l i+  + ++  ++   +++f+   g+++s
  EEA18646.1 284 IIRPVKmlTRSPIIIITSLFIAITYGYMYLLFTSFTEVFQRyYGFTTS 331
                 888888545555666555555555544444444445555542466666 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 0.65
                 HHHHHHHHHHHHHHHHH-TTTT.SS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHH.HHH CS
    Sugar_tr  78 slliaavlfvigavlqaaakgk.nsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwr.ill 174
                  l +a++++ +g ++ +++ +   ++ + i+g vl+Gig  l +++  my+    +   ++a+  ++ +  ++G l+  +   +++k++   gw   ll
  EEA18646.1 391 PLPFAVLCLPVGLLIYGWTAEWgLHWIIPIIGTVLIGIGQLLLYMVLQMYLIDSFTIYAASAVAAITAVRSIAGGLLPLFGLSIYDKFGV--GWGnTLL 487
                 56689999999*****9998556789999***********************99999999999999999999999998766556688888..7762445 PP

                 HCCHHHHHHHHHH CS
    Sugar_tr 175 glqlvpallllil 187
                 ++ ++p +l+++l
  EEA18646.1 488 AFVCLPLVLVSVL 500
                 5555555555554 PP

>> Wzz  Chain length determinant protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.3      0.22   9.9e+02      15      39 ..      66      90 ..      64      92 .. 0.83
   2 ?    3.0   0.0     0.029   1.3e+02      20      43 ..     224     247 ..     219     269 .. 0.88
   3 ?    5.1   0.4    0.0064        29       9      36 ..     288     315 ..     283     323 .. 0.68

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.22
                XXXXXXXXXXXXXXXXXXXXXXXXX CS
         Wzz 15 rkklIilvtllfallaviyaflatp 39
                + +lI ++t+l+al++ ++a ++++
  EEA18646.1 66 NCFLISAMTFLTALASSVIAPAVPQ 90
                568999*********9999876665 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.029
                 XXXXXXXXXXXXXXXXXXXX-EEE CS
         Wzz  20 ilvtllfallaviyaflatpkYta 43 
                 +l+++ +a+++++ +f+++++Y +
  EEA18646.1 224 WLLAISGAIISIVMLFVLKETYHT 247
                 7889999***************75 PP

  == domain 3  score: 5.1 bits;  conditional E-value: 0.0064
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
         Wzz   9 lsvLwkrkklIilvtllfallaviyafl 36 
                 +++L ++ ++Ii   +++++ +++y+++
  EEA18646.1 288 VKMLTRSPIIIITSLFIAITYGYMYLLF 315
                 5667777777777777777777777744 PP

>> Tad  Putative Flp pilus-assembly TadE/G-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.9      0.36   1.6e+03       9      24 ..     199     215 ..     193     215 .. 0.80
   2 ?   -3.7   0.6       3.6   1.6e+04      21      27 ..     232     238 ..     225     242 .. 0.38
   3 ?   -4.0   0.1         4   1.8e+04      15      28 ..     299     312 ..     296     313 .. 0.62
   4 ?   -3.1   0.8       2.4   1.1e+04      13      22 ..     339     350 ..     333     355 .. 0.55
   5 ?   -1.4   0.7      0.65   2.9e+03       7      19 ..     394     406 ..     392     410 .. 0.83
   6 ?   -2.3   0.5       1.3   5.9e+03       4      17 ..     446     458 ..     444     467 .. 0.70
   7 ?    6.9   0.0    0.0017       7.6       4      31 ..     485     511 ..     483     513 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.36
         Tad   9 lallplll.lvglavDv 24 
                 +++ p+++ ++g+ v++
  EEA18646.1 199 ALFAPIVGpMAGGFVAY 215
                 67788888999999976 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 3.6
         Tad  21 avDvgra 27 
                  + + ++
  EEA18646.1 232 IISIVML 238
                 2222222 PP

  == domain 3  score: -4.0 bits;  conditional E-value: 4
         Tad  15 lllvglavDvgrav 28 
                 +  +  a+ +g+++
  EEA18646.1 299 ITSLFIAITYGYMY 312
                 44566777888877 PP

  == domain 4  score: -3.1 bits;  conditional E-value: 2.4
         Tad  13 plll..lvglav 22 
                  l l  ++g+a+
  EEA18646.1 339 GLGLgsFIGVAI 350
                 222335888887 PP

  == domain 5  score: -1.4 bits;  conditional E-value: 0.65
         Tad   7 falallpllllvg 19 
                 fa+++lp+ ll+ 
  EEA18646.1 394 FAVLCLPVGLLIY 406
                 999****999876 PP

  == domain 6  score: -2.3 bits;  conditional E-value: 1.3
         Tad   4 avlfalallpllll 17 
                 + ++a+ +++++ +
  EEA18646.1 446 T-IYAASAVAAITA 458
                 6.777777777764 PP

  == domain 7  score: 6.9 bits;  conditional E-value: 0.0017
         Tad   4 avlfalallpllllvglavDvgravlar 31 
                 + l+a+++lpl+l+  l + +g++++++
  EEA18646.1 485 T-LLAFVCLPLVLVSVLLIRYGQTLREK 511
                 4.799999**************999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (517 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       886  (0.0494171); expected 358.6 (0.02)
Passed bias filter:                      424  (0.0236488); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.55u 0.26s 00:00:00.81 Elapsed: 00:00:00.39
# Mc/sec: 3955.53
//
Query:       EEA18647.1  [L=300]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (300 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       328  (0.0182944); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 1998.29
//
Query:       EEA18648.1  [L=613]
Description: FAD-dependent isoamyl alcohol oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.1e-15   55.7   2.6    7.2e-15   54.9   2.6    1.4  1  FAD_binding_4  FAD binding domain
    1.5e-09   37.8   0.1    1.5e-09   37.8   0.1    2.0  2  BBE            Berberine and berberine like


Domain annotation for each model (and alignments):
>> FAD_binding_4  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.9   2.6     8e-19   7.2e-15       4     136 ..     139     276 ..     136     279 .. 0.91

  Alignments for each domain:
  == domain 1  score: 54.9 bits;  conditional E-value: 8e-19
                    EEEESSHHHHHHHHHHHHHCTSCEEEESSSTTEESTTCSCCEEEEEETTS--...EEEEET...TTTEEEEETTSBHHHHHHHHHHHTTECSSGGG CS
  FAD_binding_4   4 vvrpeseeevaaalrlaneaglpvlvrGgGssllgqavatggvvldlsrlnr...ileide...eegtatveaGvtlgdlvealaakglllglepg 93 
                     + ++s+ +v+a +++a+e++++++v ++G+++ g +  ++ + l++ +l++   i+++++   ++  ++++aG  +g+ + a++++g+ +    +
     EEA18648.1 139 SINVTSARDVVAGIQFAKEKNIRLVVKNTGHDYHGRSSGSNSLSLWMYNLKTadiIHNYKSshySGPAVKLGAGMGVGESYMAVHEYGYRIV-GGE 233
                    5789******************************77777********889997765556555556999**********************97.999 PP

                    TTCGSBHHHTTTTT-EETTEEGG--HHGTEEEEEEEETTSEEE CS
  FAD_binding_4  94 sgipgtvGGaiatnagGygsekyGlirdnvlglevvladGevv 136
                    +g+ g++GG+  +++++   +  Gl +d+vl++evv+ +Ge +
     EEA18648.1 234 CGTVGVAGGYSQGGGHSVLTSENGLGSDQVLEWEVVTTNGEYL 276
                    999*************************************976 PP

>> BBE  Berberine and berberine like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.3      0.74   6.6e+03      12      21 ..     398     410 ..     379     413 .. 0.67
   2 !   37.8   0.1   1.7e-13   1.5e-09       2      39 ..     529     566 ..     528     573 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 0.74
                 H.HHHHHHHG..G CS
         BBE  12 k.ewgerYFg..g 21 
                 k e+ e+Y+   +
  EEA18648.1 398 KtEYSETYYDhfN 410
                 4488899996544 PP

  == domain 2  score: 37.8 bits;  conditional E-value: 1.7e-13
                 -TTS--GGG-HHHHHHHHGGGHHHHHHHHHHH-TT--S CS
         BBE   2 YvNyrdldlgkewgerYFggNferLvkvKtkyDPdNvF 39 
                 Y+N  d+  + +w+e+++g+N+erL  +K+kyDPd++ 
  EEA18648.1 529 YMNEVDPLYKGDWKEAMYGANYERLLGIKNKYDPDHLL 566
                 9*****99999************************975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (613 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       406  (0.0226449); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.26s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 3921.68
//
Query:       EEA18649.1  [L=521]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-27   96.3   0.9    2.3e-27   95.5   0.9    1.4  1  FAD_binding_4  FAD binding domain
     0.0025   17.9   0.0     0.0054   16.8   0.0    1.6  1  BBE            Berberine and berberine like


Domain annotation for each model (and alignments):
>> FAD_binding_4  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.5   0.9   2.5e-31   2.3e-27       1     138 [.      87     222 ..      87     223 .. 0.96

  Alignments for each domain:
  == domain 1  score: 95.5 bits;  conditional E-value: 2.5e-31
                    EEEEEEESSHHHHHHHHHHHHHCTSCEEEESSSTTEE.STTCSCCEEEEEETTS--EEEEETTTTEEEEETTSBHHHHHHHHHHHTTECSSGGGTT CS
  FAD_binding_4   1 paavvrpeseeevaaalrlaneaglpvlvrGgGssll.gqavatggvvldlsrlnrileideeegtatveaGvtlgdlvealaakglllglepgsg 95 
                    pa+++ pes  +va+a+++a++ + ++ v +gG+    g++  +gg++++l ++n+ ++++e++ t+ v++G ++ d++++l+  ++++    g +
     EEA18649.1  87 PACIFLPESSHDVASAVQIARRSNCHFAVKSGGHAAFsGASNSDGGLTINLAAMND-ITVNEDRATVSVGPGNRWVDVYRRLENLNRTVV--GGRI 179
                    899*********************************9777779********99***.8************************88788877..9*** PP

                    CGSBHHHTTTTT-EETTEEGG--HHGTEEEEEEEETTSEEEEE CS
  FAD_binding_4  96 ipgtvGGaiatnagGygsekyGlirdnvlglevvladGevvrl 138
                     +++vGG++++++++  s+++G  +dnv ++e+++a G v+++
     EEA18649.1 180 ADVGVGGLTLGGGISFFSNMHGWACDNVASYEIITASGDVLTA 222
                    ****************************************986 PP

>> BBE  Berberine and berberine like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.0     6e-07    0.0054       2      41 ..     476     513 ..     475     516 .. 0.93

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 6e-07
                 -TTS--GGG-HHHHHHHHG.GGHHHHHHHHHHH-TT--S-- CS
         BBE   2 YvNyrdldlgkewgerYFg.gNferLvkvKtkyDPdNvFrn 41 
                 Y+Ny+ +      + r +g +N ++L+ +  +yDP+ vF+ 
  EEA18649.1 476 YMNYASQFQD---PIRGYGaENVAKLQAIAEEYDPQRVFQR 513
                 99*******9...******9*******************75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (521 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       446  (0.0248759); expected 358.6 (0.02)
Passed bias filter:                      424  (0.0236488); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.69u 0.39s 00:00:01.08 Elapsed: 00:00:00.58
# Mc/sec: 2719.47
//
Query:       EEA18650.1  [L=2268]
Description: polyketide synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.7e-66  224.4   3.4    2.9e-66  223.6   0.1    2.7  3  ketoacyl-synt    Beta-ketoacyl synthase, N-terminal domain
    4.9e-62  209.0   0.2    1.6e-61  207.4   0.1    2.0  2  KR               KR domain
    4.5e-45  154.5   0.0    7.5e-45  153.8   0.0    1.3  1  Acyl_transf_1    Acyl transferase domain
    4.7e-38  131.1   0.0      8e-38  130.4   0.0    1.4  1  PS-DH            Polyketide synthase dehydratase
    9.8e-33  112.7   0.7    2.1e-32  111.6   0.7    1.6  1  Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
    1.2e-20   74.9   0.0    2.9e-20   73.7   0.0    1.7  1  ADH_zinc_N_2     Zinc-binding dehydrogenase
    7.8e-19   67.9   0.1      5e-18   65.3   0.0    2.4  2  ADH_zinc_N       Zinc-binding dehydrogenase
    7.8e-15   55.3   0.1    2.4e-09   37.7   0.0    2.9  2  KAsynt_C_assoc   Ketoacyl-synthetase C-terminal extension
    3.3e-09   37.0   0.1    8.1e-09   35.7   0.1    1.7  1  PP-binding       Phosphopantetheine attachment site
    3.5e-08   33.1   0.1    1.3e-07   31.3   0.0    1.9  2  adh_short        short chain dehydrogenase
    2.5e-06   27.3   0.2    9.1e-06   25.5   0.2    2.0  1  ADH_N            Alcohol dehydrogenase GroES-like domain
     0.0014   18.1   0.2      0.059   12.7   0.0    2.5  2  Thiolase_N       Thiolase, N-terminal domain
  ------ inclusion threshold ------
       0.11   12.2   0.0          4    7.1   0.0    2.5  1  SAT              Starter unit:ACP transacylase in aflatoxin b


Domain annotation for each model (and alignments):
>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  223.6   0.1   2.1e-69   2.9e-66       2     253 .]       8     253 ..       7     253 .. 0.94
   2 ?   -1.7   0.0       1.3   1.7e+03     184     218 ..    1916    1949 ..    1914    1954 .. 0.80
   3 ?   -0.1   0.3      0.41   5.6e+02     173     196 ..    2173    2196 ..    2162    2198 .. 0.87

  Alignments for each domain:
  == domain 1  score: 223.6 bits;  conditional E-value: 2.1e-69
                    --EEEEEEEEEBTTBSS.HHHHHHHHHTT---EEES-TTSSCGTTSBTSSTTEEE-BSS.EEE..S..TTEGGTTSTHHHHHHHCTS-HHHHHHHH CS
  ketoacyl-synt   2 epvaivGmgarfPggnd.veefwelLlegrdaiselpadrwdadklydpparaagkiktklggfld..vddfdpeffgispreaeamdpqqrllle 94 
                    ep+ai+Gm+ rf+g  +  e++w++Ll+g+ + s +       +k+y+p++  +g i++k ++f++    +fd +ffg++++e+ +mdpqqrllle
     EEA18650.1   8 EPIAIIGMASRFAGQASdIEKLWDVLLKGKPSPSAFL-----NNKHYHPDQSRQGAIHAKAAYFIKddTTAFDSAFFGMTKKEVLSMDPQQRLLLE 98 
                    89***********98888****************999.....5777789*****************9999************************** PP

                    HHHHHHHHHTS-HHTCTTGGEEEEEEESSTHHHHHHHHHHHTTGGGSCTTHHHHHSTTHHHHHHHHHHT--SSEEEEESGGGHHHHHHHHHHHHHH CS
  ketoacyl-synt  95 aawealedagltpeeldgsrvgvfiGvgagdyaalaaldedgsevkaspkavgavlanviagrisyalglrGpsvtvdtACsSslvavhaavqslr 190
                     +++ale++g++ e+  g+++ vf+G + +d +a+  +d++     ++   +g   +++ a+ris++++++G+s++vdtACsSslva+  a+q l 
     EEA18650.1  99 STYHALENSGIPLEQAIGTNTSVFVGQCGEDFGAMCNSDMEL--APTYK-ETGV-ERSIRANRISWFYNFKGASYVVDTACSSSLVALYTACQDLL 190
                    ******************************998866666555..44455.6665.99*************************************** PP

                    TTS-SEEEEEEEE---SHHHHHHHHHTTBB-TTSGGGTTBTTB-SB-BB-EEEEEEEEECHHH CS
  ketoacyl-synt 191 sgeadvalaGGvellltpeavagfsaagllspdgrckafdpkadGfvlGEGvGavvLkrleda 253
                     +++ +a++GG +++ +p++++g++++g++ +dg c afd +a+G+ +GEGvG+v++krl+da
     EEA18650.1 191 LHDSGMAVVGGIQTINHPSQFMGLDKLGAIGSDGYCYAFDSRANGYARGEGVGTVIMKRLSDA 253
                    *************************************************************98 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 1.3
                     HHHHHHHTTS-SEEEEEEEE---SHHHHHHHHHTT CS
  ketoacyl-synt  184 aavqslrsgeadvalaGGvellltpeavagfsaag 218 
                     a++++l+sg +  ++aG+ + + +     ++ a++
     EEA18650.1 1916 AFIERLQSGGC-KVVAGACDIANENDVRQFLGACK 1949
                     78999******.789***99888887777777766 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.41
                     SGGGHHHHHHHHHHHHHHTTS-SE CS
  ketoacyl-synt  173 tACsSslvavhaavqslrsgeadv 196 
                      AC+S ++a ++++++++++ +d+
     EEA18650.1 2173 GACASIAAATELIIDAIKQKLSDL 2196
                     69*****************99997 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       3.3   4.6e+03      59      87 ..     316     344 ..     310     346 .. 0.89
   2 !  207.4   0.1   1.2e-64   1.6e-61       1     179 [.    1874    2050 ..    1874    2051 .. 0.98

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 3.3
                 ---TT-HHHHHHHHHHHHHHSS---EEEE CS
          KR  59 aaDvsdkdavealleeikaeeppikGvih 87 
                 a D ++ +a+++++e++k+++p i G ++
  EEA18650.1 316 AGDATEVKALSTAFETAKRDTPLIVGAVK 344
                 6899*****************99999876 PP

  == domain 2  score: 207.4 bits;  conditional E-value: 1.2e-64
                  SEEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------T CS
          KR    1 gtylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdkll 97  
                  ++yli GGl g+G+++a+w++++gar+l+ll+Rs+ ++++ +a+i++l++ g++v + a+D++++++v++ l ++k  +ppi+G+i++A+vl+dk +
  EEA18650.1 1874 ASYLISGGLRGVGKVIAQWMVSHGARNLILLTRSGVQSPETAAFIERLQSGGCKVVAGACDIANENDVRQFLGACK-YMPPIRGCIQSAMVLKDKSI 1969
                  68*************************************************************************8.789***************** PP

                  TT--HHHHHHHHTTTTHHHHHHHHHTTTS--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHHHHHTEEEEEE--BT CS
          KR   98 eemtaedleqvlapKvkGawnLhelledesldffvlfSSiagllgsagqanYaaaNaflDalaeyrrsqglpavsinwglwa 179 
                   +mt ed+ ++++pKv+G+wnLh+ll+  +ldffv++SSi g++g+ gqanYaa+N+f+D+la+yr sqgl+a+s+++++++
  EEA18650.1 1970 LNMTHEDWIAAIRPKVNGSWNLHKLLP-MDLDFFVMLSSITGVIGNHGQANYAAGNTFQDQLARYRVSQGLRATSLDLSAIS 2050
                  **************************9.7************************************************99875 PP

>> Acyl_transf_1  Acyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  153.8   0.0   5.5e-48   7.5e-45       2     282 ..     592     889 ..     591     906 .. 0.85

  Alignments for each domain:
  == domain 1  score: 153.8 bits;  conditional E-value: 5.5e-48
                    EEE--TT---TTTTCCHHHC-HHHHHHHHHHHHHCCHH.HT--HHHHHHS--TTGGGSHHHHHHHHHHHHHHHHHHHHHTT-TTSEEEE-TTHHHH CS
  Acyl_transf_1   2 fvfsGqGsQwaGMGmeLlktskafaaviaradeafksq.ygfsvldvlrnnpeglldaiqfvqpaLaavqialaellkskGvrpaavvGHSlGElA 96 
                    f+f+GqG+Qw GM  +L +  k ++ +i+ a+  f ++ + + ++++l+       d+     p ++++q+a ++ll+s Gv+p  vvGHS GE+A
     EEA18650.1 592 FIFTGQGAQWDGMIGALSQF-KTYRRSIEDAAVYFTEMgSQWNLTELLDHRVILDRDDLALNLPLVTVLQVAIIDLLHSWGVKPRCVVGHSSGEVA 686
                    9****************999.9*************997568***********88888899999********************************* PP

                    HHHHCCSSSHHHHHHHHHHHHHHHHHHTS-.EECCEECS.HHHHH..HH.....TT.EEEEEEECCCCECCEEHHHHHHHHHHHHHCC.CCEEECC CS
  Acyl_transf_1  97 aavvagalsseeallavvlrsrlmmqlagp.gdmaavelaeeeek..lr...cqddvvgavansprrvvisgsqealrelvervskegvgalvenv 186
                    aa++ g +    a +a+++r+ + ++l+g+ g+m+av+l++e+ k  +r      +++ a++nsp++ +isg  +a+++l + +  e ++a++ nv
     EEA18650.1 687 AAYASGKIGRKAAWKAAYFRGVVAAKLSGQgGGMLAVALSPEKAKdyIRdyeAAGKLTIACYNSPSNQTISGDIDAIDALKATLDDEKIFARKLNV 782
                    ****************************76268******55554411442234568**************************************** PP

                    CEECTTCCCCCCCCHHHHHHHHCCCHHCHHTTBEHCCCHHH.......HHHCHHHHHHHHHHHCHCCHCCHHTTS.SSEC..C-CCEECSSSSCCH CS
  Acyl_transf_1 187 nvavhspqvdaiadalasaladiaprkpkvakisstsldes.......serelsaeywvanlrspvrfaeavlsa.aeti..plvfveispHslll 272
                    + a hs  +   a++  s l d+     k+  +s +++ +s       s++  +  yw +nl+spv+f  a+l++  e++   +  +ei pHs+l+
     EEA18650.1 783 SNAYHSSHMTVGAEEYTSLLGDLH-TDDKLLGWSDVEMISSvtglsltSKQLEQPSYWTNNLVSPVQFTSALLKMcNESGiaFDDLLEIGPHSTLQ 877
                    ***************999999955.4555555555555555566666566666779*******************65544114567********** PP

                    CCCCCCCHH..G CS
  Acyl_transf_1 273 aalektlks..a 282
                     a+++tl++   
     EEA18650.1 878 SAVNETLHDtlS 889
                    ********7332 PP

>> PS-DH  Polyketide synthase dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  130.4   0.0   5.8e-41     8e-38       2     294 ..     971    1292 ..     970    1296 .. 0.88

  Alignments for each domain:
  == domain 1  score: 130.4 bits;  conditional E-value: 5.8e-41
                  TTB.-EE--.-SS-EEEEEEE-S-SS.TTTSEEETTEEB--TTHHHHHHHHHHHHTS---....-EEEEEEEE----.B--SS.-EEEEEEEEE-TT CS
       PS-DH    2 pllGsrvrsasdkevvfrnrlrlaelpwLrDHrvdgkvvlPgagylemaleAarqltges...kavelrdvsilkalvlpede.pvevqlslepeed 94  
                  +l+G+ v+  + +++ +r+ +r++e pw+ +H++ g++++ gag + ma+e arql+  s   ++++lr+v++++ l++pe++ +vev++s++   d
  EEA18650.1  971 DLIGAPVPDWDFDHPKWRQFFRVKEIPWITEHKITGQIIMAGAGWVVMAVEGARQLADPSlkvTGFRLREVALKSTLIIPETDeGVEVMISMQWMSD 1067
                  799******************************************************9999999*******************************88 PP

                  S-E.......EEEEEEE-SS-TT.EEEEEEEEEE-----...........--B--HHHHHHHS-SEE....E-HHHHHHHHHHHSEEE-GGG--EEE CS
       PS-DH   95 gad...rawvefeifSregggeewtehatGtvrlaegaa...........aaavdlealqarcaepaslrsvssaefYerlaargleyGpsFqglra 177 
                  ++    + w ef+i+S++++++ w++ha+G v+++ ++            a++ +++ l  ++ ++   ++v+s+  Y r++ +g+++  ++++l++
  EEA18650.1 1068 SSEtvsNIWREFTITSHDQESNTWRVHAKGLVSIEYEQSnisidkndkllAEESAAKRLL-AEVTENCKTPVDSEWMYGRFRPAGFDFKTRYKNLSQ 1163
                  8889********************************999*******99973334444443.33333344679************************* PP

                  EEEETT....EEEEEE---..GGGSSTTTT....-SB-HHHHHHHHHHG..GG..----------EEEEEEEEEEE-S....-BTS--EEEEEE--- CS
       PS-DH  178 lwrgdg....ealaelrlp..eelaggesa....yvlhPallDaalQllaaal..saeaekadaaylPvaierlrvyr.pssaageelwvharleee 261 
                  +  ++g    ++l+++r p  +  + +++     ++ h ++lD+++++ + ++    ++ +  ++ +P  +++++++   ss+ag+ l+  ++  ++
  EEA18650.1 1164 ISISKGpdcyDVLGTVRNPdlA--SVTAAGyvypHLYHTVTLDSVIHMGLPTIlaRLDNGSVPSPTIPGWFDEVWISSsISSRAGDALRLCMHQYND 1258
                  **99666667899999999552..4333334555777**********8888778966789999****************9999******99999777 PP

                  -SS-EEEEEEEE-.SS-BEEEEEESEEEEE--XX CS
       PS-DH  262 garsivadltlvd.edGrvvaeieglrlrrvere 294 
                    ++++ +++ +d ++ + +++i+gl+ + v+ +
  EEA18650.1 1259 FWHGLRNEIVGFDeHSSKRMLHIKGLKYHTVPGN 1292
                  78999********88999********99988765 PP

>> Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.6   0.7   1.5e-35   2.1e-32       2     117 ..     262     377 ..     261     378 .. 0.99

  Alignments for each domain:
  == domain 1  score: 111.6 bits;  conditional E-value: 1.5e-35
                      EEEEEEEEEE--STSSSTSTTHHHHHHHHHHHHHHHT--GGGEEEEE-SS-SSHHHHHHHHHHHHHHHGGGGGSCTSEEE-THHHH-B-GGGHH CS
  Ketoacyl-synt_C   2 avikgsavnsdgahnsltapngeaqaraiekalaeagvdpedvdyveahgtgtplgDpiElealkkvfgekarkqplavgSvKsniGHleaAaG 95 
                      avi+ s+++s+g++ ++ +p++eaq ++i+  +++ag+d +  + veahgtgt++gD++E++al+++f++ +r+ pl vg+vK+ +GH+e+AaG
       EEA18650.1 262 AVIRSSSASSNGRTPGIFNPSAEAQTALIKTTYQKAGLDLALTTFVEAHGTGTKAGDATEVKALSTAFETAKRDTPLIVGAVKTILGHTEGAAG 355
                      89******************************************************************************************** PP

                      HHHHHHHHHHHHHTEE--BTT- CS
  Ketoacyl-synt_C  96 vaelikvvlalkhgvipptlnl 117
                      ++++ikvv++l++g+ip + n+
       EEA18650.1 356 ILSVIKVVKMLETGIIPRNHNF 377
                      *******************997 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.7   0.0   2.1e-23   2.9e-20       3     133 .]    1713    1850 ..    1711    1850 .. 0.87

  Alignments for each domain:
  == domain 1  score: 73.7 bits;  conditional E-value: 2.1e-23
                    -SEEEETTSTTHH....HHH-TT-EEEEEES-HHHHH.HHHHHHEEEEEEEEE--.--.S-EEE-CHHHCTTT-EEEE--GGG...-....-HHH CS
  ADH_zinc_N_2    3 Adevidyrtedfe....aatggegvDvvldtvggealleaslkvlpggGrlvsig.gpplsaallkpakkrkgrsvkyeflfsmkas...aqadi 89  
                    Ad+++ +rt df     +atgg gvDvvl++++geal ++sl+++++ Gr++++g +++ s++ll+ ++ +k+ s+ ++ ++++ ++      ++
    EEA18650.1 1713 ADHIFSSRTFDFDtlimEATGGHGVDVVLNSLAGEAL-RRSLDCVAPLGRFIELGkKDVYSNGLLQMKALKKSVSFFAVDMLTLYKHreeYSGKL 1806
                    9***********************************9.*******888*******7777777766666667777777777766333356636666 PP

                    HHHHHHHHHHHH----EEEEEEGGGHHHHHHHHHSS--SSEEEE CS
  ADH_zinc_N_2   90 leelaalieeGklrpvvdrvfpleeaaeAhrylesgrarGKiVl 133 
                    lee  +l+ +G ++ ++ ++++++++  A+r+l++g ++GKiVl
    EEA18650.1 1807 LEETIDLLTKGVIKLPLVETYSFADMLPAFRKLQTGNMMGKIVL 1850
                    *******************************************8 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0       2.1   2.9e+03      55      91 ..     163     205 ..     140     218 .. 0.59
   2 !   65.3   0.0   3.6e-21     5e-18       1     112 [.    1676    1790 ..    1676    1809 .. 0.80

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 2.1
                 TTSSEEEEEESSCSHHHHHHHHHC....EEEEEEEEECSC..T CS
  ADH_zinc_N  55 ggegvdvvfecvGsgatleaalkl....lkpgGrlvvvGg..g 91 
                 + +g+ +v++++ s + +  ++++    l+  G+ vv G+   
  EEA18650.1 163 NFKGASYVVDTACSSSLVALYTACqdllLHDSGMAVVGGIqtI 205
                 4458888888888555554444322222555677777776443 PP

  == domain 2  score: 65.3 bits;  conditional E-value: 3.6e-21
                  HHHHHHHHHHHHTT-EEEEEESSHHHHHHHHH.TT..ESEEEETTTC.HHHHHHHHHTTTSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSC..T CS
  ADH_zinc_N    1 gvGlaavqlAkalGaeviavdsseeklelakk.lG..adevinykea.dlverikeltggegvdvvfecvGsgatleaalkllkpgGrlvvvGg..g 91  
                  g G+aa+q+A+  Gae+++++sseek +++ + +G  ad+++ + ++ d++  i e+tgg gvdvv++ ++ g++l+++l++++p Gr+   G   +
  EEA18650.1 1676 GTGQAAIQYARLVGAEIFTTVSSEEKKRYLIEtYGvaADHIFSS-RTfDFDTLIMEATGGHGVDVVLNSLA-GEALRRSLDCVAPLGRFIELGKkdV 1770
                  78*****************9988888888777699988999999.888***********************.*********************7443 PP

                  SSEEEEEHHHHHHTT-EEEEE CS
  ADH_zinc_N   92 kgeeefdlrnlllkeksilGs 112 
                  + +  +  ++ l+k++s+  +
  EEA18650.1 1771 YSNG-LLQMKALKKSVSFFAV 1790
                  3333.3333345555555554 PP

>> KAsynt_C_assoc  Ketoacyl-synthetase C-terminal extension
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.7   0.0   1.7e-12   2.4e-09       2      45 ..     381     426 ..     381     445 .. 0.93
   2 !   14.3   0.1   3.1e-05     0.043      46     111 ..     490     563 ..     475     564 .. 0.71

  Alignments for each domain:
  == domain 1  score: 37.7 bits;  conditional E-value: 1.7e-12
  KAsynt_C_assoc   2 npeipaleegrlkVvteptpwpggi...vgvNsfGfGGsnvHviLks 45 
                     npei+  e+++++ + e+++wp++    +++NsfGfGG+n+H++++ 
      EEA18650.1 381 NPEID-TEKLNIRFPLETMKWPREGvrrASINSFGFGGANAHAVIDD 426
                     89***.****************998899****************986 PP

  == domain 2  score: 14.3 bits;  conditional E-value: 3.1e-05
  KAsynt_C_assoc  46 nkkekrkeeskeeslprLlvlsgrteeaveallekleeh........lldaellsllneilseeisrlpyRGya 111
                     n + +++ + +++ +++L+v+s+ +++++++++e+++ +        ++d  +++ l+++l++++s +++R+y+
      EEA18650.1 490 NGNSQSNGKLEHDTRKNLFVFSAFDKKGLKRIAESYQGWlqhalqqeEQDFGFITRLAYTLAHHRSMFNWRSYI 563
                     333444444447899********************99884444322233344566899999999999*****96 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.7   0.1   5.9e-12   8.1e-09       1      65 [.    2187    2251 ..    2187    2253 .. 0.96

  Alignments for each domain:
  == domain 1  score: 35.7 bits;  conditional E-value: 5.9e-12
  PP-binding    1 eklrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaa 65  
                  +++++ +++++ +p+e+i++  +++++G+DSl+ave+ ++l++e  ++i + ++   ++++ +a 
  EEA18650.1 2187 DAIKQKLSDLISTPAEDINDRKTFSSYGVDSLVAVEFRSWLSAEIATDIAVLEIIGSRSIRTIAG 2251
                  579999*******************************************************9986 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.0       4.9   6.7e+03     127     144 ..    1663    1680 ..    1643    1710 .. 0.58
   2 !   31.3   0.0   9.3e-11   1.3e-07       4     155 ..    1877    2026 ..    1875    2042 .. 0.89

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 4.9
                  TTEEEEEEEEGGGTSB-T CS
   adh_short  127 ssGrIvnvsSvagkvpva 144 
                  ssG+ + + S ag  + a
  EEA18650.1 1663 SSGEKILIHSGAGGTGQA 1680
                  556666666666654443 PP

  == domain 2  score: 31.3 bits;  conditional E-value: 9.3e-11
                  EEESTTSHHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHT...TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGC CS
   adh_short    4 lvtGassGIGraiakelakeGakvvv.vdrseekleevakelkee...gakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfsel 96  
                  l+ G+ +G+G+ ia+ +++ Ga+ ++ + rs  +  e+a+ ++++   g k++a ++D++++++v++++ ++ k + ++   ++ A + +++++ ++
  EEA18650.1 1877 LISGGLRGVGKVIAQWMVSHGARNLIlLTRSGVQSPETAAFIERLqsgGCKVVAGACDIANENDVRQFLGAC-KYMPPIRGCIQSAMVLKDKSILNM 1972
                  799********************9998888877776666666666555999******************999.899********************* PP

                  SHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHH CS
   adh_short   97 seeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaa 155 
                  + e+w + i   ++g  +l +++   ++       v  sS++g  ++ g+a Y+A   +
  EEA18650.1 1973 THEDWIAAIRPKVNGSWNLHKLLPMDLD-----FFVMLSSITGVIGNHGQANYAAGNTF 2026
                  *******************998766666.....89******************997555 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.5   0.2   6.6e-09   9.1e-06       2      61 ..    1556    1610 ..    1555    1623 .. 0.91

  Alignments for each domain:
  == domain 1  score: 25.5 bits;  conditional E-value: 6.6e-09
                  TEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS--TT-EEEE CS
       ADH_N    2 gevlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkklkvGdrVvv 61  
                  +ev +kv+++g++  D+ +  g      + + + G E +G + +vg +v+++kvGdrV+ 
  EEA18650.1 1556 DEVQVKVATVGLNFRDVVVSLG-----EQNEDVYGIEGAGWITQVGTAVTEFKVGDRVAG 1610
                  89*****************999.....467779*************************85 PP

>> Thiolase_N  Thiolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   0.0   4.3e-05     0.059      79     117 ..     169     207 ..     163     217 .. 0.89
   2 ?    2.5   0.0     0.056        77      23      84 ..     655     716 ..     648     800 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 4.3e-05
                 EEEEHGGGHHHHHHHHHHHHHHTTSHSEEEEEEEEESTT CS
  Thiolase_N  79 vtvnkvcsSglkavalaaqsiaageadvvvagGvEsmsn 117
                   v+ +csS+l a+++a+q +   ++ ++v+gG  ++ +
  EEA18650.1 169 YVVDTACSSSLVALYTACQDLLLHDSGMAVVGGIQTINH 207
                 5799*****************************987766 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.056
                 HHHHHHHHHHHHHHHHTS-GGGCCEEEEEHSSCTTSTSCHHHHHHHHTTS-TTSEEEEEEHG CS
  Thiolase_N  23 aeeLlaealkallekagvdpeevdevivGnvlqagegqniarqaalkagipeevpavtvnkv 84 
                  +  l+ a+ +ll++ gv+p +v     G+v++a +   i r+aa ka   + v+a  +  +
  EEA18650.1 655 LVTVLQVAIIDLLHSWGVKPRCVVGHSSGEVAAAYASGKIGRKAAWKAAYFRGVVAAKLSGQ 716
                 5667889999************************9999999*99999988787777776655 PP

>> SAT  Starter unit:ACP transacylase in aflatoxin biosynthesis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.0    0.0029         4     150     240 .]     709     787 ..     630     787 .. 0.64

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0029
         SAT 150 vaarleegsssssesWslavtglseeelekalaefneekglppasrvyisavssss.vtisGpPstleallksskakkkkkksklpiyapyH 240
                 vaa+l+ g+       +lav+ ls e++++++ ++ +  +      + i++++s+s  tisG  ++++al ++   +k   + kl ++++yH
  EEA18650.1 709 VAAKLS-GQGG----GMLAVA-LSPEKAKDYIRDYEAAGK------LTIACYNSPSnQTISGDIDAIDALKATLDDEKIFAR-KLNVSNAYH 787
                 333333.2222....566666.888888888888888777......669999998889999999999988888888888776.899999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2268 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       369  (0.0205812); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 1.22u 0.39s 00:00:01.61 Elapsed: 00:00:00.59
# Mc/sec: 11492.95
//
Query:       EEA18651.1  [L=456]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-10   39.7   0.0    3.1e-08   32.6   0.0    2.1  2  AATase    Alcohol acetyltransferase


Domain annotation for each model (and alignments):
>> AATase  Alcohol acetyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.6   0.0   1.7e-12   3.1e-08      73     190 ..      71     172 ..      41     208 .. 0.79
   2 !    4.9   0.0   0.00043       7.7     368     478 ..     319     424 ..     293     432 .. 0.76

  Alignments for each domain:
  == domain 1  score: 32.6 bits;  conditional E-value: 1.7e-12
      AATase  73 skPfpkeDyvkviekiklddvvlneqpeysellekileeykdddekvdeelnellselvipvgdpkkPlwrlivlpsaddkkkwkkfv.fitdHllfDG 170
                 ++P     + + ++ ++ldd +             i ++  d+d +  +    l s +    +dp  P wr+++lp  ++  k + f+ +++ H++ DG
  EEA18651.1  71 KEP-----FWELVPSLNLDDHI-----------SVIDKQVVDEDDETAAIERALPSIVDQRFTDPSVPPWRIVILPFTSGS-KSRCFIaYVSSHSTADG 152
                 455.....66777778888877...........45556667777777766667777777899***************7555.89999************ PP

      AATase 171 isgvnffkdlleelekikqd 190
                 +sg  f++  le l+k  + 
  EEA18651.1 153 VSGYFFHRKFLEALQKPVDS 172
                 **************986554 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.00043
      AATase 368 skeklwelveeyhkrlseslsn.gkelkglgtlildlllkyvnidkllkkkilktkrstaevsNlGlfsq.eeeskykvkdliFsqaagslknafslnv 464
                   +k w  +++++++lse  s  ++++ g++           +    + +k+   + + + +sN+  f    e+s  k++  +   +a   +++f++++
  EEA18651.1 319 ISDKTWADAKSLTEKLSECSSKlEDQMIGMI-------RFVPDHAASMMQKLGGPRDASFALSNINAFDGvIEKSICKITKFLMTTSAAVHSAPFTFCI 410
                 4577899999999999994332133444443.......444566778889999999999******999988******************9********* PP

      AATase 465 istnsgGlnlslsv 478
                  s++ g l + ++ 
  EEA18651.1 411 ASVKGGNLICVVTW 424
                 ***99988777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (456 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       329  (0.0183502); expected 358.6 (0.02)
Passed bias filter:                      316  (0.0176251); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.45
# Mc/sec: 3042.81
//
Query:       EEA18652.1  [L=2894]
Description: polyketide synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.6e-73  246.3   0.0    1.2e-72  244.6   0.0    1.9  2  ketoacyl-synt    Beta-ketoacyl synthase, N-terminal domain
    9.3e-52  175.5   0.1    4.8e-50  170.0   0.1    2.7  2  KR               KR domain
    2.1e-43  148.7   0.1    4.3e-43  147.6   0.1    1.6  1  PS-DH            Polyketide synthase dehydratase
      3e-42  145.3   0.1    5.3e-42  144.4   0.1    1.3  1  Acyl_transf_1    Acyl transferase domain
    4.7e-29  101.3   0.0    8.4e-29  100.5   0.0    1.4  1  NAD_binding_4    Male sterility protein
    2.3e-28   98.6   0.0    5.5e-28   97.3   0.0    1.7  1  Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
    1.5e-19   70.6   0.0    5.1e-19   68.9   0.0    2.1  1  Methyltransf_12  Methyltransferase domain
      3e-14   53.4   0.0    1.2e-13   51.5   0.0    2.1  1  KAsynt_C_assoc   Ketoacyl-synthetase C-terminal extension
    8.2e-14   51.8   0.0    7.6e-13   48.6   0.0    2.3  2  Methyltransf_23  Methyltransferase domain
      9e-14   51.4   0.0    1.3e-12   47.6   0.2    2.7  3  adh_short        short chain dehydrogenase
    8.3e-13   48.9   0.0      4e-12   46.7   0.0    2.3  1  Methyltransf_25  Methyltransferase domain
    1.8e-11   44.6   0.0    9.2e-11   42.2   0.0    2.4  1  Methyltransf_11  Methyltransferase domain
    1.5e-10   41.0   0.0    5.1e-08   32.7   0.0    2.7  2  Epimerase        NAD dependent epimerase/dehydratase family
    6.3e-09   35.8   0.0    1.8e-08   34.3   0.0    1.7  1  Methyltransf_31  Methyltransferase domain
    3.7e-08   33.0   0.0    8.3e-08   31.8   0.0    1.5  1  Ubie_methyltran  ubiE/COQ5 methyltransferase family
    3.7e-05   23.4   2.0    4.1e-05   23.3   0.2    2.0  2  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    4.6e-05   22.6   0.0    0.00049   19.2   0.0    2.2  2  3Beta_HSD        3-beta hydroxysteroid dehydrogenase/isomeras
    6.6e-05   22.4   0.1    0.00015   21.2   0.1    1.5  1  Thiolase_N       Thiolase, N-terminal domain
  ------ inclusion threshold ------
      0.013   15.8   0.1      0.093   13.1   0.1    2.4  2  PP-binding       Phosphopantetheine attachment site
      0.014   14.6   0.0       0.99    8.5   0.0    2.5  2  NNMT_PNMT_TEMT   NNMT/PNMT/TEMT family
      0.042   14.3   0.0       0.38   11.2   0.0    2.5  2  Secretin_N       Bacterial type II/III secretion system short
       0.18   11.7   0.5          1    9.2   0.3    2.3  2  ACP_syn_III      3-Oxoacyl-[acyl-carrier-protein (ACP)] synth


Domain annotation for each model (and alignments):
>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  244.6   0.0   1.5e-75   1.2e-72       2     253 .]       7     256 ..       6     256 .. 0.97
   2 ?   -2.4   0.0       3.5   2.8e+03      20      76 ..     892     945 ..     889     960 .. 0.78

  Alignments for each domain:
  == domain 1  score: 244.6 bits;  conditional E-value: 1.5e-75
                    --EEEEEEEEEBTTBSS.HHHHHHHHHTT---EEES-TTSSCGTTSBTSSTTEEE-BSS.EEE..S..TTEGGTTSTHHHHHHHCTS-HHHHHHHH CS
  ketoacyl-synt   2 epvaivGmgarfPggnd.veefwelLlegrdaiselpadrwdadklydpparaagkiktklggfld..vddfdpeffgispreaeamdpqqrllle 94 
                    ep+aivG ++rf+g  + ++++w+ L e rd  +e+  dr++ + +y+p++  +g++++ ++++ld     fd+effg++p ea+a+dpqqrll+e
     EEA18652.1   7 EPIAIVGSACRFAGEASsPSKLWDILKEPRDLRREVT-DRFKIKSFYHPDSSHHGHSNVTHAYLLDedLGGFDAEFFGVKPVEAKAIDPQQRLLME 101
                    89***********99999*******************.7***************************9899************************** PP

                    HHHHHHHHHTS-HHTCTTGGEEEEEEESSTHHHHHHHHHHHTTGGGSCTTHHHHHSTTHHHHHHHHHHT--SSEEEEESGGGHHHHHHHHHHHHHH CS
  ketoacyl-synt  95 aawealedagltpeeldgsrvgvfiGvgagdyaalaaldedgsevkaspkavgavlanviagrisyalglrGpsvtvdtACsSslvavhaavqslr 190
                    +++e le+ag++ + l+gs++gv++Gv+ gdy+++++ d+d+  + ++  a+g+  ++++++r+sy+++++Gps+++dtACsSsl avh+avqslr
     EEA18652.1 102 VVYEGLESAGMDMNGLRGSDTGVYVGVMVGDYGTMTLRDMDQ--SPTYY-ATGT-GRSILSNRVSYFFDWHGPSISIDTACSSSLIAVHMAVQSLR 193
                    ********************************9999999888..45666.8998.9**************************************** PP

                    TTS-SEEEEEEEE---SHHHHHHHHHTTBB-TTSGGGTTBTTB-SB-BB-EEEEEEEEECHHH CS
  ketoacyl-synt 191 sgeadvalaGGvellltpeavagfsaagllspdgrckafdpkadGfvlGEGvGavvLkrleda 253
                    sge+ +a+a+G++l+l+pe+++  s++++lspdgr++  d++a+G+ +GEGv+ +vLk+l+ a
     EEA18652.1 194 SGESRMAVACGSNLILGPENFIIESKLKMLSPDGRSRMWDEGANGYARGEGVASIVLKTLSAA 256
                    ***********************************************************9876 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 3.5
                    HHHHHHHHTT---EE...ES-TTSSCGTTSBTSSTTEEE-BSS.EEE..STTEGGTTSTH CS
  ketoacyl-synt  20 eefwelLlegrdais...elpadrwdadklydpparaagkiktklggfldvddfdpeffg 76 
                     ++  ++l g+++++    lp+ +w+ ++ y +++r+  ki++ +      + f p++  
     EEA18652.1 892 NDYEVAMLGGKKCFQvlkGLPSYQWNHERSYWHETRMSRKIYQTQ------EPFHPMLGH 945
                    566778899999999888999999******999999999999954......444554444 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  170.0   0.1   5.9e-53   4.8e-50       1     177 [.    2117    2290 ..    2117    2293 .. 0.96
   2 ?    2.6   0.0      0.14   1.2e+02       3      34 ..    2572    2604 ..    2570    2622 .. 0.84

  Alignments for each domain:
  == domain 1  score: 170.0 bits;  conditional E-value: 5.9e-53
                  SEEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------T CS
          KR    1 gtylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdkll 97  
                  +ty i+G  G+LGl+la+w+++kgar++vl+sR+  +d  + +++a+ +++ga+v v+a+ v++++ ++ + ++ik++ ppi Gv++ A+vlrd  +
  EEA18652.1 2117 STYWIVGMSGALGLSLADWMISKGARNVVLTSRN--PD-VAPEWLAAHKRRGATVAVFACNVTNEKGMHDVHRQIKETLPPIVGVMNGAMVLRDVSI 2210
                  59********************************..34.4456****************************************************** PP

                  TT--HHHHHHHHTTTTHHHHHHHHHTTTS--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHHHHHTEEEEEE-- CS
          KR   98 eemtaedleqvlapKvkGawnLhelledesldffvlfSSiagllgsagqanYaaaNaflDalaeyrrsqglpavsinwgl 177 
                   +m+ ++l+ vl+pKv G+  L++++  ++ldffv++SSi  ++g+ gqanYaaaN+f+ ala++rr++gl+a ++n g+
  EEA18652.1 2211 RNMSYQELTDVLNPKVIGSIILDKMFYTTDLDFFVFVSSINCVIGNLGQANYAAANTFMCALAAQRRKRGLRAATVNGGA 2290
                  ***************************************************************************99776 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.14
                  EEEETTTSHHHHHHHHHHHHHH.S-EEEEE-SS CS
          KR    3 ylitGGlGgLGlelarwlaekg.arhlvllsRs 34  
                   ++tG++G LG +l +  +e+  ar++ +l+ +
  EEA18652.1 2572 IVLTGAAGLLGHHLLNYFLENTpARKIHCLAVR 2604
                  589****************99999999988766 PP

>> PS-DH  Polyketide synthase dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  147.6   0.1   5.3e-46   4.3e-43       1     291 [.     940    1242 ..     940    1249 .. 0.86

  Alignments for each domain:
  == domain 1  score: 147.6 bits;  conditional E-value: 5.3e-46
                  BTTB.-EE--.-SS-EEEEEEE-S-SS.TTTSEEETTEEB--TTHHHHHHHHHHHHTS---.....-EEEEEEEE----.B--SS.-EEEEEEEEE- CS
       PS-DH    1 hpllGsrvrsasdkevvfrnrlrlaelpwLrDHrvdgkvvlPgagylemaleAarqltges....kavelrdvsilkalvlpede.pvevqlslepe 92  
                  hp+lG+  + +++++++++n lr +e+ wL+ H+v+ ++v+P+agyl+ a+eA  +l+++     + +e+++++i++a+ +++d   +ev +++   
  EEA18652.1  940 HPMLGHLTPDSAPHQMIWKNLLRENEMYWLAGHKVQSQTVFPAAGYLSSAMEASSHLAESVneaiRLIEIKNFVIHQAIAFDQDHpDIEVLIQMANV 1036
                  9*********************************************************888889999******************999999999887 PP

                  TTS-E......EEEEEEE-SS-TT..EEEEEEEEEE-------B--HHHHHHHS-SEE....E-HHHHHHHHHHHSEEE-GGG--EEEEEEETTEEE CS
       PS-DH   93 edgad..rawvefeifSregggee.wtehatGtvrlaegaaaaavdlealqarcaepaslrsvssaefYerlaargleyGpsFqglralwrgdgeal 186 
                  + ++   r  ++f+ +++ ++ +e  t+ a+G v++  g++    +++ l++r ++ +++ +v+ + fY++la+ g+++  +F+ l++l+r  + ++
  EEA18652.1 1037 KHERKsnRILATFTYSAVLSAVAEdFTLAASGDVEILLGEP----SASLLPTRPPPLSHVIDVETDNFYNALADLGYNFSGRFRSLSSLHR--KHYR 1127
                  66655774445555444444444446*************99....66777777888888888*****************************..7777 PP

                  EEE---.GGGSSTTTT-SB-HHHHHHHHHHG..GG.----------EEEEEEEEEEE-S........-BTS--EEEEEE..----SS-EEEEEEEE- CS
       PS-DH  187 aelrlp.eelaggesayvlhPallDaalQllaaal.saeaekadaaylPvaierlrvyr.....pssaageelwvharl..eeegarsivadltlvd 274 
                  a++ ++ + l++ge ++++hP+ lDa+lQ++++a+    +e+ ++  lP++i+r+r+++      ++++ge + v++ +  ++ ++r+i+++++l+ 
  EEA18652.1 1128 ATCLVKmQPLSEGEFPLLIHPTELDAVLQSIILAYsYPYDEQLRTIHLPTSIQRIRINPalcnaTAWQQGEFAPVDSAIvpRKPDERGITGHVQLYS 1224
                  7777776788888888*************998999945689*****************97777655555555555555588999************* PP

                  .SS-BEEEEEESEEEEE- CS
       PS-DH  275 .edGrvvaeieglrlrrv 291 
                   +d+ + ++++g ++ ++
  EEA18652.1 1225 yADQHAAIQVQGASFMPF 1242
                  9**********9988776 PP

>> Acyl_transf_1  Acyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  144.4   0.1   6.5e-45   5.3e-42       3     288 ..     550     857 ..     549     878 .. 0.82

  Alignments for each domain:
  == domain 1  score: 144.4 bits;  conditional E-value: 6.5e-45
                    EE--TT---TTTTCCHHHC-HHHHHHHHHHHHHC.....CHHHT--HH.HHHHS--TTGGGSHHHHHHHHHHHHHHHHHHHHHTT-TTSEEEE-TT CS
  Acyl_transf_1   3 vfsGqGsQwaGMGmeLlktskafaaviaradeaf.....ksqygfsvl.dvlrnnpeglldaiqfvqpaLaavqialaellkskGvrpaavvGHSl 92 
                    +f+GqG+Q a MG+eL+++++++++ i+++++++     k+   +s+  ++l++ +++ +++ + +qp  +a+q+ l++ l+ +G + +avvGHS 
     EEA18652.1 550 IFTGQGAQYARMGAELIENNEVAREIIREMENHLaalpsKDRPTWSLErEILAAPETSRVSEAVLSQPLCTAIQVLLVDILRMAGIEFDAVVGHSS 645
                    8********************************94433345678***6489999999*************************************** PP

                    HHHHHHHHCCSSSHHHHHHHHHHHHHHHHHH.......TS-EECCEECS.....HHHHHHH...TT.EEEEEEECCCCECCEEHHHHHHHHHHHHH CS
  Acyl_transf_1  93 GElAaavvagalsseeallavvlrsrlmmql.......agpgdmaavel....aeeeeklr.cqddvvgavansprrvvisgsqealrelvervsk 176
                    GE+Aaa++ag l++ +a+  ++ r +l  q        +++g+m av+       e ++    q +++ a+ ns ++v++sg ++a++el   +  
     EEA18652.1 646 GEIAAAYAAGFLTARDAIYIAYYR-GLHVQFaasptgrSVKGAMVAVGSskedMDELCADEmFQGRISIAANNSTSSVTVSGDEDAIAELQDILDD 740
                    *****************9877655.555554122222246799****99443222233333355678999************************** PP

                    CC.CCEEECCCEECTTCCCCCCCCHHHHHHHH..CCCHHCHH..TTBEHCCCHHH.HHHCHHHHHHHHHHHCHCCHCCHHTTS.SSECC-CCEECS CS
  Acyl_transf_1 177 egvgalvenvnvavhspqvdaiadalasalad..iaprkpkv..akisstsldes.serelsaeywvanlrspvrfaeavlsa.aetiplvfveis 266
                    e  + ++ +v+ a hs+ + a  +   + l    i p+kp+     +ss++ +       l + yw++n+ +pv+f +a+  a a   ++  +e+ 
     EEA18652.1 741 EKKFNRKLRVDTAYHSNHMLACVKPYIESLRRcgISPQKPNTkcVWYSSVYNKLVdHDMALGDVYWADNMAKPVLFYDALVTAlASNSYDLAMEVG 836
                    *****************99887777777777667888887541044566666665566778899***************999989999******** PP

                    SSSCCHCCCCCCCHHGGG-TCC CS
  Acyl_transf_1 267 pHslllaalektlksaedvksa 288
                    +H+ l   + +t++++ ++k+ 
     EEA18652.1 837 AHPALKGPGTQTIQEV-QGKDI 857
                    *************974.34444 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.5   0.0     1e-31   8.4e-29       1     254 [.    2574    2805 ..    2574    2808 .. 0.83

  Alignments for each domain:
  == domain 1  score: 100.5 bits;  conditional E-value: 1e-31
                     EE-TTSHHHHHHHHHHHHHS-.TEEEEEE-SSSHHHHHHHHHHHT-SS-HHHHHHHHHTTTEEEEE--TTSGGGG--HHHHHHHHHH--EEEE- CS
  NAD_binding_4    1 lTGaTGFLGkvLlekLLrttpevkiyllvRaksgesaeeRleeelekkelfsallkelaerikvveGDlseprlGLseedlqelaeevdviihs 94  
                     lTGa G LG +Ll+  L++tp+ ki++l+  k       Rl    +++el+      +  r++  eGDl+ p lGLse+++ ++ +e dv+ih+
     EEA18652.1 2574 LTGAAGLLGHHLLNYFLENTPARKIHCLAVRK----LSTRL----ANNELP------VNPRVIYHEGDLTLPLLGLSEKEAADIFSEADVVIHN 2653
                     8********************88*****5544....23466....555554......478********************************** PP

                     -SS-S.STTSSEEHHHHHHHHHHHHHHHTSSS--.-EEEEEE.GGGTTS-TTT--SSS-H......HHH--EEEETTTCCCHHHHHHHHHHHHH CS
  NAD_binding_4   95 aAtvnfdepykellrvNveGtrevlelakklkklkvllhvST.ayvngeregeveekvyeegekeekldederaklkglpntYeqsKalaEklv 187 
                     + ++++ +  ++++ +N  +tr++ +l+  + +  ++++vS+ +++  +++ ++   ++        +  d++    + + +Y  sK++ E+ +
     EEA18652.1 2654 GSDTSHLKFFPDMRTANCGSTRDLTRLCLPR-RI-PFHYVSSvGVCVLYSQPAFPPVPV--------TGPDSMLPAPDGTFGYMCSKWVNERFL 2737
                     *****************************44.44.7******87777777766533322........333444444455559************ PP

                     HHHHHHH---EEEEEE-EEE-..-SSST---TTSHHHHHHHHHHHH-EEES-SB---TT--EEEHHHHH CS
  NAD_binding_4  188 rearrrsglpvvivRpsiitg..esktGwingsdlgirgllgliakgvlpeilgdkeavldlvpvDyva 254 
                     ++ ++  glpv i+Rps+i+   +  t +  + d +++ ll +++k +    ++++++ ldlv++ +++
     EEA18652.1 2738 EQVHDIYGLPVYIHRPSTIIRegDDATNARAELD-WVNALLHYAKKIKAVPHVKHNRGALDLVSIKTAC 2805
                     ********************98877788999999.666666666666666688888999***9987776 PP

>> Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.3   0.0   6.8e-31   5.5e-28       2     115 ..     265     390 ..     264     393 .. 0.93

  Alignments for each domain:
  == domain 1  score: 97.3 bits;  conditional E-value: 6.8e-31
                      EEEEEEEEEE--STSSSTSTTHHHHHHHHHHHHHHHT--.GGGEE...EEE-SS-SSHHHHHHHHHHHHHHHGGGGG........SCTSEEE-T CS
  Ketoacyl-synt_C   2 avikgsavnsdgahnsltapngeaqaraiekalaeagvd.pedvd...yveahgtgtplgDpiElealkkvfgekar........kqplavgSv 83 
                      ++i+++a+n+dga+ ++t p+++aq+ +i++++ +ag+d  + +d   y eahgtgtp+gDpiE++a++++f  +++         qpl+vgS+
       EEA18652.1 265 CIIRETATNQDGATDGITMPSAAAQESLIRSIYTRAGLDlQSPIDrphYFEAHGTGTPAGDPIEAQAIHNAFYGSSKgnlqlnsdCQPLYVGSI 358
                      5799**********************************9645565555***********************9988888999999989******* PP

                      HHHH-B-GGGHHHHHHHHHHHHHHHTEE--BT CS
  Ketoacyl-synt_C  84 KsniGHleaAaGvaelikvvlalkhgvipptl 115
                      K+ +GH+e+ aG+a+++k+  a+++g+ipp++
       EEA18652.1 359 KTVLGHTEGTAGIAAVLKASEAIRRGTIPPNM 390
                      ******************************97 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.9   0.0   6.2e-22   5.1e-19       1      99 []    1424    1525 ..    1424    1525 .. 0.91

  Alignments for each domain:
  == domain 1  score: 68.9 bits;  conditional E-value: 6.2e-22
  Methyltransf_12    1 LeiGcGtGsllrallekl..pdieytgvDispsaiedakeklakrennnnnnvelealdlldldgg.ssfDlvvasnvlhhlkdirevldni 89  
                       Le+G+GtG  ++a+ +++  ++++yt++Dis+ ++ +a+  +++++++   +  + ++d ld+    +s+Dl+va++v+h++ d++++l++i
       EEA18652.1 1424 LEVGAGTGGATKAIFREIgsSFKSYTYTDISAGFFGNAAGIFSQHRDRMIFKTFNAENDPLDQGFVeGSYDLIVAFFVIHATSDLEKSLRHI 1515
                       8*******************************************99988777777767666554448************************* PP

  Methyltransf_12   90 rklLkpgGrl 99  
                       r+lLkpgG l
       EEA18652.1 1516 RRLLKPGGFL 1525
                       ********86 PP

>> KAsynt_C_assoc  Ketoacyl-synthetase C-terminal extension
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.5   0.0   1.4e-16   1.2e-13      13     109 ..     406     507 ..     397     509 .. 0.86

  Alignments for each domain:
  == domain 1  score: 51.5 bits;  conditional E-value: 1.4e-16
  KAsynt_C_assoc  13 lkVvteptpwpggi.....vgvNsfGfGGsnvHviLksnkkekrkeeskeeslprLlvlsgrteeaveallekleeh.lldaellsllneilsee 101
                     l+++  + pwp+ +     ++vNsfGfGGsn+H+iL+s++++ ++++++       lv+s+ +e++++  l++++e+ +++ + l++++ +++ +
      EEA18652.1 406 LEIPVAAKPWPQLAigprrASVNSFGFGGSNAHAILESYDNTASSSSKT---VFGPLVFSALSEKSLRCSLSAYAEYlTNEGDSLNIADLAFTLR 497
                     7788889999998888999***********************9999999...9999*********************555567778777777766 PP

  KAsynt_C_assoc 102 isr..lpyRG 109
                      +r  +pyR+
      EEA18652.1 498 QRRtaFPYRA 507
                     6666699996 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.6   0.0   9.3e-16   7.6e-13       7     117 ..    1405    1527 ..    1398    1582 .. 0.83
   2 ?   -0.3   0.0         1   8.4e+02      89     121 ..    1827    1859 ..    1821    1885 .. 0.83

  Alignments for each domain:
  == domain 1  score: 48.6 bits;  conditional E-value: 9.3e-16
  Methyltransf_23    7 eelsdklerllpklraggrvLdiGcGtG.illevlrengf...svtgvDlspeaveiae.....kakkaqkdqfdeqeaaepqg....kfdl 85  
                       +++s+ +++l++ +++ +++L++G+GtG  +  ++re g    s+t  D+s    + a+      ++ ++++ f++++++ +qg    ++dl
       EEA18652.1 1405 QWVSRTVKQLVE-RFPHMNILEVGAGTGgATKAIFREIGSsfkSYTYTDISAGFFGNAAgifsqHRDRMIFKTFNAENDPLDQGfvegSYDL 1495
                       567778888887.99*************5555555998644469*******8777777798889888888888877766666667777**** PP

  Methyltransf_23   86 IvlrevlehvpdppellrqiatllkpgGylll 117 
                       Iv+++v++   d+++ lr+i++llkpgG l++
       EEA18652.1 1496 IVAFFVIHATSDLEKSLRHIRRLLKPGGFLVV 1527
                       *****************************997 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 1
  Methyltransf_23   89 revlehvpdppellrqiatllkpgGylllsepl 121 
                       +++ +++++  ++   + ++ +p+G++ ++++ 
       EEA18652.1 1827 SDSGCSIKNQSKYEVELLEHNNPDGLIHFQTSH 1859
                       5666999999999999999**********9964 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0      0.76   6.2e+02      62      90 ..    1405    1433 ..    1379    1466 .. 0.78
   2 !   47.6   0.2   1.6e-15   1.3e-12       5     182 ..    2121    2291 ..    2117    2304 .. 0.90
   3 ?   -3.6   0.0       7.9   6.4e+03       1      24 [.    2570    2593 ..    2570    2631 .. 0.64

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.76
                  HHHHHHHHHHHHHHSSESEEEE---SS-- CS
   adh_short   62 eevealvekavkklgkldvLvnNAGitgs 90  
                  + v+++v++ v+++ ++++L  +AG  g 
  EEA18652.1 1405 QWVSRTVKQLVERFPHMNILEVGAGTGGA 1433
                  568899*******************9433 PP

  == domain 2  score: 47.6 bits;  conditional E-value: 1.6e-15
                  EESTTSHHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCSHHH CS
   adh_short    5 vtGassGIGraiakelakeGakvvv.vdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfselseee 100 
                  ++G s+ +G+ +a+ ++++Ga+ vv ++r+++ + e+++  k+ ga++ +++++vt+++ + ++ +++++ l ++  ++n+A + +++++ ++s +e
  EEA18652.1 2121 IVGMSGALGLSLADWMISKGARNVVlTSRNPDVAPEWLAAHKRRGATVAVFACNVTNEKGMHDVHRQIKETLPPIVGVMNGAMVLRDVSIRNMSYQE 2217
                  99*******************999889********************************************************************** PP

                  HHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSB CS
   adh_short  101 wervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlv 182 
                    +v++  + g + l ++++++         v+vsS+++  ++ g+a Y+A+    + ++ +la + +++g r  +v+ G++
  EEA18652.1 2218 LTDVLNPKVIGSIILDKMFYTT----DLDFFVFVSSINCVIGNLGQANYAAA----NTFMCALAAQRRKRGLRAATVNGGAI 2291
                  ******************9998....44589******************987....66666777777777777777766655 PP

  == domain 3  score: -3.6 bits;  conditional E-value: 7.9
                  SEEEEESTTSHHHHHHHHHHHHTT CS
   adh_short    1 kvvlvtGassGIGraiakelakeG 24  
                  +v++ tGa++ +G+ + + ++++ 
  EEA18652.1 2570 NVIVLTGAAGLLGHHLLNYFLENT 2593
                  58999****999999988888764 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.7   0.0   4.9e-15     4e-12       1      97 []    1423    1523 ..    1423    1523 .. 0.92

  Alignments for each domain:
  == domain 1  score: 46.7 bits;  conditional E-value: 4.9e-15
                       EEEET-TTSHHHHHHHCTST..SSEEEEEESSHHHHHHHHHHHHHTTTTEEEEESBCCGBS....SSTTTEEEEEEESTGGGSSHHHHHHHH CS
  Methyltransf_25    1 vLdlGcGtGrltlalakrlg..kakvtgvDiseemleaareraeeeglnvefvqgdaedlp....fedgsfDlvvssgalhhlsdedlekal 86  
                       +L++G+GtG  t+a+ +++g   +++t +Dis+++  +a+  +++++ ++ f + +ae+ p    f +gs+Dl+v+++++h +s  dlek l
       EEA18652.1 1423 ILEVGAGTGGATKAIFREIGssFKSYTYTDISAGFFGNAAGIFSQHRDRMIFKTFNAENDPldqgFVEGSYDLIVAFFVIHATS--DLEKSL 1512
                       8*****************95569********************998889***9999988665566899********99999876..99**** PP

                       HHHHHHEEEEE CS
  Methyltransf_25   87 keiarvLkpgG 97  
                       ++i+r+LkpgG
       EEA18652.1 1513 RHIRRLLKPGG 1523
                       **********9 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.2   0.0   1.1e-13   9.2e-11       1      96 []    1424    1527 ..    1424    1527 .. 0.83

  Alignments for each domain:
  == domain 1  score: 42.2 bits;  conditional E-value: 1.1e-13
                       EEET-TTSHHHHHHHHTT....SEEEEEES-HHHHHHHHHHCCHHT-EEEETTEECCC....TSS-TT-EEEEEEES-CCC-CCHHHHHHHH CS
  Methyltransf_11    1 LdvGcGtGrlaealakrg....arvvgvDlskemlklakekaseeglkvefvvadaek....lpfednsfDlvvssevlhhvedpekalkei 84  
                       L+vG+GtG  ++a+ +      ++++ +D+s+ +   a    s+ + ++ f   +ae+      f ++s+Dl+v+++v+h   d+ek l+ i
       EEA18652.1 1424 LEVGAGTGGATKAIFREIgssfKSYTYTDISAGFFGNAAGIFSQHRDRMIFKTFNAENdpldQGFVEGSYDLIVAFFVIHATSDLEKSLRHI 1515
                       89*************4444888*************888655555555666666677753311569999************************ PP

                       HHHEEEEEEEEE CS
  Methyltransf_11   85 aRvLkpgGllvi 96  
                       +R+LkpgG+lv+
       EEA18652.1 1516 RRLLKPGGFLVV 1527
                       *********986 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.014        11       3     123 ..    2121    2258 ..    2119    2317 .. 0.72
   2 !   32.7   0.0   6.3e-11   5.1e-08       1     176 [.    2572    2760 ..    2572    2798 .. 0.75

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.014
                  EETTTSHHHHHHHHHHHHCTSE.EEEEES-STTTTCHHCHHC......EEEE--TT-HH...HHHHHHHHH..T-SEEEE--S.---HH...HHHHS CS
   Epimerase    3 VtGatGfiGsalvkallekgye.vigldrlssasntarledl......elveldltdrs...alerlfkee..qpdavihlAa.vggva...assed 83  
                  ++G +G +G  l++ + +kg + v+  +r+++  ++++ +++       +  +++t+++   +++r +ke+   +  v++ A    +v+    s ++
  EEA18652.1 2121 IVGMSGALGLSLADWMISKGARnVVLTSRNPDVAPEWLAAHKrrgatvAVFACNVTNEKgmhDVHRQIKETlpPIVGVMNGAMvLRDVSirnMSYQE 2217
                  89******************88577777777777777777779*****999******9977777777777742233344445444444310023344 PP

                  HHHHHHHHTHHHHHHHHHHHHHTCTEEEEEEE.GGGGTSCS CS
   Epimerase   84 padfieknlqgtlnlleaarkagvkrllflsS.sevYGkda 123 
                   +d+++  ++g+  l ++  +++++ ++f+sS  +v G+  
  EEA18652.1 2218 LTDVLNPKVIGSIILDKMFYTTDLDFFVFVSSiNCVIGNLG 2258
                  45666667777777777777777777788877777777655 PP

  == domain 2  score: 32.7 bits;  conditional E-value: 6.3e-11
                  EEEETTTSHHHHHHHHHHHHCT..SEEEEEES-STTTTCHHCHHC......EEEE--TT-HH......HHHHHHHHHT-SEEEE--S.---HHHHHH CS
   Epimerase    1 ilVtGatGfiGsalvkallekg..yevigldrlssasntarledl......elveldltdrs......alerlfkeeqpdavihlAa.vggvaasse 82  
                  i++tGa+G++G +l++++le++   ++++l+ ++ + + a++e l        +e+dlt +       + +++f+  ++d+vih +   ++ +    
  EEA18652.1 2572 IVLTGAAGLLGHHLLNYFLENTpaRKIHCLAVRKLSTRLANNE-LpvnprvIYHEGDLTLPLlglsekEAADIFS--EADVVIHNGSdTSHLKF--- 2662
                  789*******************975588888886555555544.3478999889999885544443337778888..89******664444444... PP

                  SHHHHHHHHTHHHHHHHHHHHHHTCTEEEEEEE...GGGGTSCSS..SSBSTCSTTS--.--SSHHHHHHHHHHHHHHHHHHHHT-EEEEEEESEEE CS
   Epimerase   83 dpadfieknlqgtlnlleaarkagvkrllflsS...sevYGkdae..qpkeettltgpl.kpnspYaaaKlageklveayaaqyglnaiilrlfnly 173 
                     d+  +n+  t++l   +  + +  ++++sS   + +Y ++a   +p +      p    +  Y ++K   e+ +e++++ ygl++ i r+++++
  EEA18652.1 2663 -FPDMRTANCGSTRDLTRLCLPRRI-PFHYVSSvgvCVLYSQPAFppVPVTGPDSMLPApDGTFGYMCSKWVNERFLEQVHDIYGLPVYIHRPSTII 2757
                  .4455568*****************.*******7744557766653345333333346678899******************************998 PP

                  STT CS
   Epimerase  174 Gpr 176 
                   ++
  EEA18652.1 2758 REG 2760
                  777 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.3   0.0   2.2e-11   1.8e-08       4     113 ..    1420    1531 ..    1418    1556 .. 0.91

  Alignments for each domain:
  == domain 1  score: 34.3 bits;  conditional E-value: 2.2e-11
  Methyltransf_31    4 glrvlDlGCGtGeltfelaeelgpkae.vvGiDiseeaielArenaqklgldnveFeqgdiee..leklledekfDlilsnevlnaladpdk 92  
                       ++++l++G+GtG  t+++++e+g+  + ++  Dis+     A  + +++  d++ F+  ++e+  l++ + + ++Dli+++ v++a++d++k
       EEA18652.1 1420 HMNILEVGAGTGGATKAIFREIGSSFKsYTYTDISAGFFGNAAGIFSQHR-DRMIFKTFNAENdpLDQGFVEGSYDLIVAFFVIHATSDLEK 1510
                       699*********************8888999*************999887.689999999998766655555******************** PP

  Methyltransf_31   93 ileeiervlkpggilliedpr 113 
                        l+ i r+lkpgg l++ + +
       EEA18652.1 1511 SLRHIRRLLKPGGFLVVGEGQ 1531
                       ****************98877 PP

>> Ubie_methyltran  ubiE/COQ5 methyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.8   0.0     1e-10   8.3e-08      34     153 ..    1405    1529 ..    1396    1542 .. 0.79

  Alignments for each domain:
  == domain 1  score: 31.8 bits;  conditional E-value: 1e-10
                       HHHH.HHHHH--S--TTEEEEES-TT-HHHHHHHHHHHHHHE.EEEEES-HHHHHHHHHHHHHHTSSTEEEEE--TTT-T....TS-T-EEE CS
  Ubie_methyltran   34 lWkk.fveklvavkrgakvlDvagGtgDlafklsdsvgekgk.vvvlDinenmLkvgekklkeegkinieflqanaeeLp....feddsfDv 119 
                        W +  v++lv   +  ++l+v +Gtg  + ++ +++g+++k  +  Di++  +  +      +   ++ f + nae+ p    f ++s+D+
       EEA18652.1 1405 QWVSrTVKQLVERFPHMNILEVGAGTGGATKAIFREIGSSFKsYTYTDISAGFFGNAAGIFS-QHRDRMIFKTFNAENDPldqgFVEGSYDL 1495
                       57773445555555667************************725789******998876554.4455566666666665522336679**** PP

                       EEEES-GGG-S-HHHHHHHHHHHEEEEEEEEEEE CS
  Ubie_methyltran  120 vtvsfGlrnvtDklkaLkeayrvlkpGGrlvvle 153 
                       +   f +  ++D +k+L++++r lkpGG lvv e
       EEA18652.1 1496 IVAFFVIHATSDLEKSLRHIRRLLKPGGFLVVGE 1529
                       *****************************99866 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.1       5.5   4.5e+03       2      25 ..    1945    1968 ..    1945    1975 .. 0.88
   2 !   23.3   0.2     5e-08   4.1e-05       5     175 ..    2127    2292 ..    2123    2326 .. 0.81

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 5.5
                    TTTSHHHHHHHHHHHTT-EEEEEE CS
  adh_short_C2    2 aasgIGraiAkalaeeGaevvltd 25  
                    aa g+++ai  ++ e+G +vv+t+
    EEA18652.1 1945 AAVGVAEAIENLACEKGVHVVYTY 1968
                    67899****************998 PP

  == domain 2  score: 23.3 bits;  conditional E-value: 5e-08
                    SHHHHHHHHHHHTT-E.EEEEESSGGHHHHHHHHHHHTTSEE..EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHH CS
  adh_short_C2    5 gIGraiAkalaeeGae.vvltdlneeakkrveelaeelgaev..lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreefd 96  
                     +G  +A  + ++Ga+ vvlt +n + + +  +++++ ga+v  ++c+Vt+e+ ++++ ++++e++  + +++n a + ++   ++ ++s +e+ 
    EEA18652.1 2127 ALGLSLADWMISKGARnVVLTSRNPDVAPEWLAAHKRRGATVavFACNVTNEKGMHDVHRQIKETLPPIVGVMNGAMVLRD--VSIRNMSYQELT 2219
                    579999*********77**********88888888888877446*****************************99999999..************ PP

                    HHHHHHTHHHHHHHHHHHHHCTSCCEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BH CS
  adh_short_C2   97 raldvnlyslfllakaalplmkeggsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpik 175 
                    ++l+ ++ + + l k +    ++    v +ss+   ++  +++ y+aa    + ++ +lA++  ++g R  +v  g+i 
    EEA18652.1 2220 DVLNPKVIGSIILDKMFY--TTDLDFFVFVSSINCVIGNLGQANYAAA----NTFMCALAAQRRKRGLRAATVNGGAII 2292
                    *********999888774..4555788999999888888888888766....556666788888888888888777775 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.29   2.4e+02      49     126 ..    2170    2259 ..    2120    2268 .. 0.48
   2 !   19.2   0.0     6e-07   0.00049       1     120 [.    2573    2697 ..    2573    2704 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.29
   3Beta_HSD   49 viegDvtdkdkleealegvd.....vvihlaslvdvag....kltedeimkv...nvkGTrnvleacvkagvrvlvYtSsaevvgpnslg 126 
                  v  + vt+++ ++++ ++++     +v ++ +++ ++     +++ +e+ +v    v G   + ++  ++++ ++v++Ss++ v +n  +
  EEA18652.1 2170 VFACNVTNEKGMHDVHRQIKetlppIVGVMNGAMVLRDvsirNMSYQELTDVlnpKVIGSIILDKMFYTTDLDFFVFVSSINCVIGNLGQ 2259
                  666666666665555555542222222233333322221001112222222221145565555566677899999******999988765 PP

  == domain 2  score: 19.2 bits;  conditional E-value: 6e-07
   3Beta_HSD    1 vvtGgaGFlGralvkeLvrleelkevrvlDlrespe.lleelskvnvkk.viegDvt......dkdkleealegvdvvihlaslvdvagkltedeim 89  
                  v+tG+aG lG++l + +++  ++++++ l +r+ ++ l ++   vn +  ++egD+t      ++++  +   ++dvvih  +   ++ k+  d + 
  EEA18652.1 2573 VLTGAAGLLGHHLLNYFLENTPARKIHCLAVRKLSTrLANNELPVNPRViYHEGDLTlpllglSEKEAADIFSEADVVIHN-GSDTSHLKFFPD-MR 2667
                  68*****************************9876514455556666557*****9755555578999999*********9.444455557677.99 PP

   3Beta_HSD   90 kvnvkGTrnvleacvkagvrvlvYtSsaevv 120 
                  ++n   Tr +   c+   +++  Y+Ss++v 
  EEA18652.1 2668 TANCGSTRDLTRLCLPRRIPF-HYVSSVGVC 2697
                  9******************95.6****9986 PP

>> Thiolase_N  Thiolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.1   1.9e-07   0.00015      75     112 ..     168     205 ..     160     208 .. 0.92

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 1.9e-07
                 TSEEEEEEHGGGHHHHHHHHHHHHHHTTSHSEEEEEEE CS
  Thiolase_N  75 evpavtvnkvcsSglkavalaaqsiaageadvvvagGv 112
                 + p++ ++ +csS+l av++a+qs+++ge+ ++va+G 
  EEA18652.1 168 HGPSISIDTACSSSLIAVHMAVQSLRSGESRMAVACGS 205
                 568899*******************************6 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0       3.8   3.1e+03      29      61 ..     484     515 ..     483     520 .. 0.72
   2 ?   13.1   0.1   0.00011     0.093       8      63 ..    2415    2471 ..    2409    2475 .. 0.79

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 3.8
  PP-binding  29 lDSllavellaaleeefgveiplsdlfehptla 61 
                 +DSl++++l+  l+++  +++p +   + ++++
  EEA18652.1 484 GDSLNIADLAFTLRQRR-TAFPYRASIAASSIG 515
                 7************9983.555555555555555 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 0.00011
  PP-binding    8 aevlgv..pleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlael 63  
                  ++vl+v  ++eei  ++   + GlDSl++v++ +++  +++v+ip+  ++ +   ++l
  EEA18652.1 2415 RKVLQVttSDEEI-MEAEGAEIGLDSLVSVDIRSWFLNTLQVSIPVLKIMGNEPMSSL 2471
                  5666664444445.588899**************************999987655555 PP

>> NNMT_PNMT_TEMT  NNMT/PNMT/TEMT family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0     0.054        44       6      66 ..    1374    1429 ..    1370    1453 .. 0.84
   2 ?    8.5   0.0    0.0012      0.99     145     198 ..    1480    1528 ..    1467    1534 .. 0.78

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.054
                      CHHHHHHHHCB-HHHHHHHHCSTTTTSTCCCCHHHHHHHHHHHHHHTSSS-ECEEEEET-T CS
  NNMT_PNMT_TEMT    6 llakeeyvkkFepraYLekyykkasedaaeeqvvlfaLknllqtlatgekkgdtllDiGaG 66  
                      +++k++  ++F +++ L+ yy++  +     q v  + k l+++++   +   ++l++GaG
      EEA18652.1 1374 FAGKTTILEHFRANDILDRYYATGFGLRESGQWVSRTVKQLVERFP---H--MNILEVGAG 1429
                      67889999*************9999888888999999999****99...2..467899988 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0012
                      SSSTTTTSS-SS..EEEEEEESSHHHH-SSHHHHHHHHHHHHTTEEEEEEEEEE CS
  NNMT_PNMT_TEMT  145 qspvvlagvqlpkkadvvvtifcleaacedleeylralrnlasllkpGGhlvlg 198 
                      +++++  g  +    d +v++f + a+ +dl    ++lr++ +llkpGG+lv+g
      EEA18652.1 1480 ENDPLDQG-FVEGSYDLIVAFFVIHAT-SDL---EKSLRHIRRLLKPGGFLVVG 1528
                      56677664.677778999999998765.455...589***************87 PP

>> Secretin_N  Bacterial type II/III secretion system short domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   0.00047      0.38      42      74 ..     707     739 ..     699     740 .. 0.91
   2 ?   -1.5   0.0       4.1   3.3e+03       8      22 ..    1750    1764 ..    1748    1814 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00047
                 T-TTSEEEEETTTTEEEEEECHHHHHHHHHHHH CS
  Secretin_N  42 lgkggrvvadprtNsllvrgspervarirqlik 74 
                  ++++++ a+ +t s+ v+g+++ +a+++++++
  EEA18652.1 707 FQGRISIAANNSTSSVTVSGDEDAIAELQDILD 739
                 5899*************************9986 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 4.1
                  SS-HHHHHHHHHHHC CS
  Secretin_N    8 yasaadlasiLrell 22  
                  +asa+ +a+iL ++ 
  EEA18652.1 1750 NASAEAVAEILLRFH 1764
                  99********98775 PP

>> ACP_syn_III  3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.3    0.0013         1       3      35 ..     174     206 ..     172     209 .. 0.92
   2 ?   -1.3   0.0       2.5     2e+03      12      31 ..    2128    2146 ..    2124    2151 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0013
                  EE-GGGHHHHHHHHHHHHHHTTS-SEEEEEEEE CS
  ACP_syn_III   3 lnaaCsgfvyalsvAdaliesgaakrvLvigae 35 
                  + +aCs+ ++a+++A + ++sg+ + ++ +g++
   EEA18652.1 174 IDTACSSSLIAVHMAVQSLRSGESRMAVACGSN 206
                  678************************999986 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 2.5
                   HHHHHHHHHHHTTS-SEEEE CS
  ACP_syn_III   12 yalsvAdaliesgaakrvLv 31  
                    +ls+Ad +i++g a++v++
   EEA18652.1 2128 LGLSLADWMISKG-ARNVVL 2146
                   69***********.666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2894 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       448  (0.0249875); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                        22  (0.00122706); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              22  [number of targets reported over threshold]
# CPU time: 1.30u 0.35s 00:00:01.65 Elapsed: 00:00:00.54
# Mc/sec: 16167.99
//
Query:       EEA18653.1  [L=574]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.5e-41  141.3  49.4    6.3e-41  140.5  47.8    2.0  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.5  47.8   3.5e-45   6.3e-41       1     352 [.      73     475 ..      73     476 .. 0.90
   2 ?   -0.4   0.0     0.024   4.4e+02     244     270 ..     535     558 ..     512     563 .. 0.59

  Alignments for each domain:
  == domain 1  score: 140.5 bits;  conditional E-value: 3.5e-45
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlga 99 
                 l+la+fl+al+ s++++a+p  +++d+g s+  +g+  ++y l++a ++l++G + + ++ + v+l ++++f lg+l++++a+s+++++v+r+++G g+
  EEA18653.1  73 LCLAVFLMALDNSVITTAIP-KITDDFG-SVLDVGWYGSAYLLTTASLQLIFGKIYTFWSIKLVFLSTIAVFELGSLICAVAPSSTAFIVGRAIAGSGS 169
                 689*****************.*******.******************************9999************88888657777************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 +++f++++ +i++ +p  +r+ +igl++++++++++ gp++gg+l+++++Wr++fyi+ +++ + ++ ++l l +++++ ++  ++ ++          
  EEA18653.1 170 AGIFSGALLIITHTSPLAKRPTYIGLAGGMYGIASVAGPIIGGVLTDNVSWRWCFYINLPLGGVTALAIWLILKDPQRDVPTLQTWMDRirvldpigtl 268
                 *****************************************************************998778888888888888888888********** PP

       MFS_1 189 .............................................kgtgpaplvpawkallkdpvlw.illialllfffgfsglltllplylqevlgls 241
                                                               + ++a+ vp    +++++ +w  +l+++++ + +f+++ +++p+++q   g s
  EEA18653.1 269 iflpamvcllltlqwggskyswndgriiallvlsgvliiaflliqLRLQEAATVP--PRIFRNRSVWaGCLYGFCTSS-AFFLVIYYIPIWFQAIQGVS 364
                 ***********************************99999999987777777777..899999999*99999999998.******************** PP

       MFS_1 242 glllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllll.vlvliGfglgfv..fpsllalasdlappeeagta 337
                  ++++g+    +++ ++ +++++g l++ lg  ++ ++a ++l+ + +gl+ + + ++++  ++   +l+G+g+++   +p+++++a+  +  +     
  EEA18653.1 365 -AIESGIRNLPMMISTILMSIMVGGLVTALGYYTPFMIAAAILSSVGAGLLSTFAVHTSSGKWIgYQILFGIGYSLGsrQPLVAVQAALET--KDIPIG 460
                 .899999999999999999************955555555555555555555555566666666366668888888866777777777777..999999 PP

       MFS_1 338 sglfntagslggalg 352
                 +++++++++lgg+++
  EEA18653.1 461 TSIIMFLQTLGGMIF 475
                 ************996 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.024
       MFS_1 244 llaglllallalvgailallagrlsdr 270
                 +la+   a++a++++++++l+ +ls +
  EEA18653.1 535 FLAA---AAMAALSVFGSVLVPWLSVK 558
                 3444...33333334446666666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (574 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       668  (0.0372581); expected 358.6 (0.02)
Passed bias filter:                      289  (0.0161191); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 3961.88
//
Query:       EEA18654.1  [L=365]
Description: alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.3e-11   42.9   0.3    7.9e-11   42.0   0.3    1.4  1  ADH_zinc_N    Zinc-binding dehydrogenase
    0.00094   19.0   0.0     0.0071   16.2   0.0    2.4  3  ADH_N         Alcohol dehydrogenase GroES-like domain
     0.0014   19.7   0.0      0.003   18.6   0.0    1.6  1  ADH_zinc_N_2  Zinc-binding dehydrogenase


Domain annotation for each model (and alignments):
>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.0   0.3   1.3e-14   7.9e-11       3      83 ..     178     257 ..     176     263 .. 0.91

  Alignments for each domain:
  == domain 1  score: 42.0 bits;  conditional E-value: 1.3e-14
                 HHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTESEEEETTTCHHHHHHHHHTTTSSEEEEEESSCSHHHHHHHHHCEEEEE CS
  ADH_zinc_N   3 GlaavqlAkalGaeviavdsseeklelakklGadevinykeadlverikeltggegvdvvfecvGsgatleaalkllkpgG 83 
                 G++a+ql++ +G  +iav+ss++ +++a+++Ga  v +y++ +  e ik+l gg ++ +v++c+ + ++   +++l+++ G
  EEA18654.1 178 GTMACQLLRLAGYAPIAVASSKS-AAMAMEYGAIGVADYTSSTCAETIKQLAGGAPIRYVLDCITTAESAALCFSLIARTG 257
                 9*********************8.8**************5549**********************9999999999887764 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   1.2e-06    0.0071       3      61 ..      37      93 ..      35     102 .. 0.82
   2 ?   -1.1   0.0      0.29   1.8e+03      90     108 ..     103     121 ..      95     122 .. 0.80
   3 ?   -2.0   0.0      0.55   3.3e+03      26      49 ..     273     296 ..     254     302 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.2e-06
                EEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS..--TT-EEEE CS
       ADH_N  3 evlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkk..lkvGdrVvv 61
                 vl++v a++++ +D++++++   ++       G +++G++e++g++ +   + +G+rV+ 
  EEA18654.1 37 YVLVRVLAVALNPTDFKMVQH---FPIGD-NLAGCDFCGIIEACGSNDTAnqFPIGTRVCG 93
                69*****************98...44443.467************7654445*******86 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.29
                 SS-SSSBSEEEECGGGEEE CS
       ADH_N  90 sldGgfaeyvvvpekklvk 108
                 +++G+fae v++++  l+k
  EEA18654.1 103 RQSGAFAEWVIADSGLLLK 121
                 479********99887776 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 0.55
                 TTTSSSSEE---EEEEEEEEESTT CS
       ADH_N  26 elevklplilGHEivGeveevgpe 49 
                 + +v+   ++G E  G+  ++gp 
  EEA18654.1 273 RRTVRVKEVMGFEGLGIKIDLGPT 296
                 566777889999999987777775 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0   4.9e-07     0.003       2     129 ..     208     355 ..     207     360 .. 0.65

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 4.9e-07
                   T-SEEEETT.STTHH...HHH-TT-EEEEEES-HHHHH.HHHHHHE.EEEEEEEE----.S-EEE-CHHHCTTT-EEEE--GGG...-......... CS
  ADH_zinc_N_2   2 GAdevidyr.tedfe...aatggegvDvvldtvggealleaslkvl.pggGrlvsiggpplsaallkpakkrkgrsvkyeflfsmkas......... 84 
                   GA  v dy+ ++ +e   + +gg+ + +vld++ +++ ++ +++++ + gGr+ ++ +      l++  + r++ +vk ++ f+   +         
    EEA18654.1 208 GAIGVADYTsSTCAEtikQLAGGAPIRYVLDCITTAESAALCFSLIaRTGGRYACLEE------LRPAWRTRRTVRVKEVMGFE---Glgikidlgp 295
                   67779999955555599999999***********7777799999999999***99885......22222223344444444443...2244455556 PP

                   ..............-HHHHHHHHHHHHHHH----EEEE..EEGGGHHHHHHHHHSS--SS CS
  ADH_zinc_N_2  85 .............aqadileelaalieeGklrpvvdrv..fpleeaaeAhrylesgrarG 129
                                +  ++ +e+ + ++eG l+p++ r+   +++ + + ++ l+ g ++G
    EEA18654.1 296 taysrdvnltlrkICCEATKEIQTVLDEGLLKPHPVREvtGQWQGIIDGLAMLQRGDVKG 355
                   666666666555533333588999999999999887652344666666666666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (365 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       320  (0.0178482); expected 358.6 (0.02)
Passed bias filter:                      281  (0.0156729); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.25s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2549.82
//
Query:       EEA18655.1  [L=331]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.9e-19   68.9   0.0      2e-17   63.3   0.0    2.1  2  adh_short      short chain dehydrogenase
    1.1e-12   48.0   0.1    6.5e-12   45.5   0.1    1.9  1  adh_short_C2   Enoyl-(Acyl carrier protein) reductase
    1.4e-07   31.6   0.1      2e-07   31.1   0.1    1.2  1  KR             KR domain
    8.1e-05   22.2   0.0    0.00012   21.6   0.0    1.3  1  Epimerase      NAD dependent epimerase/dehydratase family
     0.0016   17.9   0.0     0.0042   16.5   0.0    1.7  1  GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
  ------ inclusion threshold ------
       0.13   12.1   0.2       0.24   11.3   0.2    1.4  1  DUF1601        Protein of unknown function (DUF1601)


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.3   0.0   6.6e-21     2e-17       1     126 [.      32     161 ..      32     179 .. 0.90
   2 ?    3.6   0.0     0.013        39     142     190 ..     200     248 ..     196     253 .. 0.90

  Alignments for each domain:
  == domain 1  score: 63.3 bits;  conditional E-value: 6.6e-21
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT....TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGG CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee....gakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfse 95 
                 kv lvtG   G+G+++a+ l+++Gakv +++rs ek+  +++e+++       +++++++D++d + v++  e   ++ ++l+vL nNAG+   +p + 
  EEA18655.1  32 KVYLVTGSNTGVGKETARILYSKGAKVWMAARSTEKASVAIDEIRNSqpssTGSLHFLHLDLSDLSTVKQSAELFLSQEQTLHVLFNNAGVMVGTPEAT 130
                 788******************************************998876677*************************************87777777 PP

                 CSHHHHHHHHHHHTHHHHHHHHHHHHHHHHC CS
   adh_short  96 lseeewervievNltgvflltravlpamlkq 126
                  + +  e  + vN  g+ l tr+v+  + k 
  EEA18655.1 131 NTVQGHELALGVNCIGTHLFTRLVTALLAKT 161
                 777779******************9998843 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.013
                 B-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHH CS
   adh_short 142 pvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakel 190
                 p + +  Y+ sK +  +l  + a+ ++ +gi  + ++PG + +++a+++
  EEA18655.1 200 PKPATERYGISKCGAWALGVEYARRHKADGIVSVPINPGNLTSELARDQ 248
                 6778889**********************************99998876 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.5   0.1   2.2e-15   6.5e-12       4     129 ..      41     178 ..      38     266 .. 0.89

  Alignments for each domain:
  == domain 1  score: 45.5 bits;  conditional E-value: 2.2e-15
                   TSHHHHHHHHHHHTT-EEEEEESSGGH.HHHHHHHHHHTTSE...E..EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHH CS
  adh_short_C2   4 sgIGraiAkalaeeGaevvltdlneea.kkrveelaeelgae...v..lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsree 94 
                    g+G+++A+ l ++Ga+v+++ ++ e+   +++e+ ++ +++   +  l++D +d ++v++ +e   ++ ++l++l+nnag++    +p ++ + ++
    EEA18655.1  41 TGVGKETARILYSKGAKVWMAARSTEKaSVAIDEIRNSQPSStgsLhfLHLDLSDLSTVKQSAELFLSQEQTLHVLFNNAGVMVG--TPEATNTVQG 135
                   79************************9889999999998866344267************************************9..9999999*** PP

                   HHHHHHHHTHHHHHHHHHHHHHCTSC......CE..EEEEEEG CS
  adh_short_C2  95 fdraldvnlyslfllakaalplmkeg......gs..ivnlssv 129
                    + al vn+ +++l+++ +  l++++      gs  ++ lss+
    EEA18655.1 136 HELALGVNCIGTHLFTRLVTALLAKTaksepeGSvrVIWLSSF 178
                   ********************97776644455533225555555 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.1   0.1   6.7e-11     2e-07       2     107 ..      33     138 ..      32     159 .. 0.82

  Alignments for each domain:
  == domain 1  score: 31.1 bits;  conditional E-value: 6.7e-11
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-.EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealga.evevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdkllee 99 
                 +yl+tG   g+G+e+ar l++kga+ + + +Rs ++ + + ++i++ + + + + +++++D+sd + v++  e + ++e++++  ++ Agv+  ++ ++
  EEA18655.1  33 VYLVTGSNTGVGKETARILYSKGAK-VWMAARSTEKASVAIDEIRNSQPSSTgSLHFLHLDLSDLSTVKQSAELFLSQEQTLHVLFNNAGVMVGTPEAT 130
                 7**********************96.7788999677777777777777664459*************************************98777766 PP

                 --HHHHHH CS
          KR 100 mtaedleq 107
                  t +  e 
  EEA18655.1 131 NTVQGHEL 138
                 66665555 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.6   0.0   4.2e-08   0.00012       2     171 ..      35     236 ..      34     258 .. 0.76

  Alignments for each domain:
  == domain 1  score: 21.6 bits;  conditional E-value: 4.2e-08
                 EEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC..........EEEE--TT-HHHHHH....HHHHH.T-SEEEE--S..---HHHHHHS CS
   Epimerase   2 lVtGatGfiGsalvkallekgyevigldrlssasntarledl..........elveldltdrsaler....lfkee.qpdavihlAa..vggvaassed 83 
                 lVtG +  +G+ +++ l +kg +v+  +r +++   a +e            ++ +ldl d s +++    ++++e   ++ ++ A+  vg+++a+++ 
  EEA18655.1  35 LVTGSNTGVGKETARILYSKGAKVWMAARSTEKASVAIDEIRnsqpsstgslHFLHLDLSDLSTVKQsaelFLSQEqTLHVLFNNAGvmVGTPEATNTV 133
                 8*****************************77777665555599*****************99665422225556647777788777778888887765 PP

                 HHHHHH..HHTHHH...HHHHHHHHHHTCT.......EEEEEEE..GGGGTSCSS.SSBSTCST.TS----SSHHHHHHHHHHHHHHHHHHHHT-EEEE CS
   Epimerase  84 padfie..knlqgt...lnlleaarkagvk.......rllflsS..sevYGkdae.qpkeettl.tgplkpnspYaaaKlageklveayaaqyglnaii 166
                 +   +    n++gt   ++l+ a+ ++ +k       r++ lsS   e++G+ +  +   ++++  +p + ++ Y+++K  +  l  +ya+ ++ + i+
  EEA18655.1 134 QGHELAlgVNCIGThlfTRLVTALLAKTAKsepegsvRVIWLSSfgLELFGAENVgV-ALDNLDyHEPKPATERYGISKCGAWALGVEYARRHKADGIV 231
                 5443332388887744457777777665555566777*******9999***998843.3444440455599*********9999999999999988888 PP

                 EEESE CS
   Epimerase 167 lrlfn 171
                   + n
  EEA18655.1 232 SVPIN 236
                 77766 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   1.4e-06    0.0042       1      70 [.      35     102 ..      35     258 .. 0.60

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 1.4e-06
                    EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHH CS
  GDP_Man_Dehyd   1 LiTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkgDltDssslerl 70 
                    L+TG +  +G  +a+ L +kg +v+   r +++ +   i+++++++  + +++l++ + Dl+D s +++ 
     EEA18655.1  35 LVTGSNTGVGKETARILYSKGAKVWMAARSTEK-ASVAIDEIRNSQ-PSSTGSLHFLHLDLSDLSTVKQS 102
                    89**9999****************987766555.557788887655.45689***********9988763 PP

>> DUF1601  Protein of unknown function (DUF1601)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.2     8e-05      0.24       8      32 ..      86     110 ..      85     112 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 8e-05
     DUF1601   8 leeqrLserLlvaIrrnaerFNsQe 32 
                 l+ + L+  +l++++++ae F sQe
  EEA18655.1  86 LHFLHLDLSDLSTVKQSAELFLSQE 110
                 56678999***************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (331 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       402  (0.0224218); expected 358.6 (0.02)
Passed bias filter:                      388  (0.0216409); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.55u 0.32s 00:00:00.87 Elapsed: 00:00:00.49
# Mc/sec: 2049.68
//
Query:       EEA18656.1  [L=551]
Description: cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-30  105.5   0.1    3.5e-29  101.9   0.1    2.0  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.9   0.1   1.9e-33   3.5e-29       5     438 ..      47     511 ..      43     521 .. 0.77

  Alignments for each domain:
  == domain 1  score: 101.9 bits;  conditional E-value: 1.9e-33
                 SEHHCCHCHHHHTT.TCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEE............SSHHHHHHHHHTTTTSSSTTC CS
        p450   5 tplplvgnllqlgr.keelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgr............pdeallatsrkpfkgkgvlfa 90 
                 +p+p + n +q+ + +e++ + ++kl  k  +i ++++g+ pv ++sg+++++++++++++  s +            + +++++ +++   g+g + a
  EEA18656.1  47 DPIPGIYNTVQFLTnNEKFMKRVMKLLSK-NSIAKFYMGTVPVYLISGTKHIQSIFGRDNKVGSEEiftqavlptlykMPKSHVERFANDKSGRGHVPA 144
                 58888999999998755555555555555.49**************************98754443111112222222467888888889999999999 PP

                 GH..HHHHHHHHHHH.HHHTSH..STT.THHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHH CS
        p450  91 ng..ekwkklRrflt.ptltsf..gkl.sleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelssl 183
                  g   + k++R      ++++        l+++++ ++++l + l+k   e+       + +  +++++ + + ++ +++l  +k  el+  + + + +
  EEA18656.1 145 PGteGTPKEQRYWARyEQIHTEylARTqHLKPIIQAYSNQLAHDLNKYPLEK-------WTTLGVVETCRREVTKCAMSTLLGPKVFELDPDFLDTFWE 236
                 8875555666654431334444663334899999999999999999999888.......7777777777777777777777777766777777777777 PP

                 HHCHHHHCCCCCH.HHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHC.SCSSCSHHHHHHHHCTTCTCT.SSSSHHHHHHHHHHHHHHHHHHHH CS
        p450 184 lskssvqllllfp.llkylptkllrklkeavkklkdlldklieerretldsa.kksrrdfldalllakkekkge.sklsdeelaatvlellfaGvdTts 279
                 +++++++l l fp +l   p++++ + k    +++ ++ +   +   +  +a ++++ +f + ++ +  +k  + s + d  +   +++llfa   +t 
  EEA18656.1 237 FDHNVFMLTLGFPkWLN--PGPYNAQDKYL-STIERYVHAAWDNFDWNGPDAeSSWEPHFGARVCREI-AKWFKeSGFPDVSISGALGTLLFAQNSNTI 331
                 77878888888886664..55444444433.6677777777777777766667778999999999987.34333479********************** PP

                 HHHHHHHHHHHHSHHHHHHHHHHHHHHCCTTT.....T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEETTEEE-TT-EEEEEHHHHHT- CS
        p450 280 stlswaLyeLaknPevqeklreEidevlgdkr.....eptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirgylipkGtevivnlyalhrd 373
                  t++w+++ + ++  + +++reE+ ++   +        +++ l  lp+l+ v  E+LRlh      + R ++++++ +gy+i+kG + +v++ a h++
  EEA18656.1 332 PTTMWMILRIFQDSCLLQAVREEVATTYSIDPvtgehICDIQKLVVLPLLQSVFTEVLRLHMNFN--IIRHAKENITMDGYNIRKGAMLQVPMMAAHYE 428
                 ***********************99987333334555778899999***************9888..78****************************** PP

                 TTTS....SSTTS--GGGGB-TTS..............CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEES CS
        p450 374 pevf....pnPeeFdpeRFldekg..............nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelq 438
                 ++v+    + + eF  eR  +  +              +  + + +++PFG Gp  C+G+++A++e+   ++ l+++F++e+ 
  EEA18656.1 429 ESVWgssgHPASEFWAERHIKYVEdtkedgkterrrvfAMAGRPSSYFPFGGGPPVCPGRHFAKHEILTTIGMLVSKFDIEVV 511
                 ****64433478999999876555667899********6679**************************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (551 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       374  (0.0208601); expected 358.6 (0.02)
Passed bias filter:                      357  (0.0199119); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.32s 00:00:00.92 Elapsed: 00:00:00.48
# Mc/sec: 3451.22
//
Query:       EEA18657.1  [L=425]
Description: benzoate 4-monooxygenase cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-62  212.0   0.0    1.7e-62  211.7   0.0    1.1  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  211.7   0.0   9.4e-67   1.7e-62      33     445 ..       2     401 ..       1     418 [. 0.86

  Alignments for each domain:
  == domain 1  score: 211.7 bits;  conditional E-value: 9.4e-67
                 H-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTS..SSTTCGHHHHHHHHHHHHHHHTSHSTT.THHHHHHHHHHHHHHH CS
        p450  33 ygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgk..gvlfangekwkklRrfltptltsfgkl.sleelveeeaedlvek 128
                 ygp++r+ +++ ++   ++p a k ++ ++  ++ g+ ++a  + +++  kg+   +++a+++++++lRr l   + ++ ++ + e+++ + +++lv++
  EEA18657.1   2 YGPVVRIAPNHLSF---TDPRAWKDIYYHRVGAVGGMVEMAKSTEFTRNVKGQltTIVNADQDEHQQLRRALSHGFSDS-SMrQQEPTMLKHINMLVDR 96 
                 78888888877554...677788888888888888888877777777777775337899999*****************.7779*************** PP

                 HHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCCCHHHTCCSCHHHH.HHHHHHHHHHHHHHHHHHH CS
        p450 129 lrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelssllskssvqllllfpllkylptkllr.klkeavkklkdlldkliee 226
                 lr+++g++   d++ + +  ++d +++++Fg++f +l++    ++  +v+++++  +++ +++ l +  +++l + + +     a+k++ +++d +++ 
  EEA18657.1  97 LRTESGKN--PDMAAWYNWTTFDLSSDLIFGESFHCLQTV---NYHPWVATIMKAIKFHAFMVALGYGGARPLVELIHKaGGFLAMKTMRGYIDSMLKS 190
                 ********..8************************99999...58999999999998999889888886666666655514566889999999999999 PP

                 HHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHCCTTTT-HHHHCCT-HHHH CS
        p450 227 rretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklreEidevlgdkreptyddlqklpyld 325
                 r +  +++     d+   l + +     +     + l  ++++ll+aG++Tt++ ls + y+L+++Pev ek++ Ei++++  +  + ++ ++kl+yl 
  EEA18657.1 191 RLAMKQRH----DDLFEGLAKRR-----D---EWDKLSVNATVLLLAGSETTATCLSGTTYFLLTHPEVLEKVTAEIRSAFSTDADINIQSVNKLTYLI 277
                 98877666....67777777775.....2...2456777888899************************************77788************* PP

                 HHHHHHHHHSCSSTTEEEEESSS.CEEETTEEE-TT-EEEEEHHHHHT-TTTSSSTTS--GGGGB-TTS...CTESSCTT--TTEEGGGS-TTHHHHHH CS
        p450 326 avikEtLRlhpvvplllpRevtk.dvvirgylipkGtevivnlyalhrdpevfpnPeeFdpeRFldekg...nskrksfaflPFGaGpRnCiGerlArm 420
                  v++E+LR++p++ +++ Rev++   +i g+++p +t v + ++++++++e + +P +F+peRF  + +   +++   +a  +F++GpRnCiG++lA+ 
  EEA18657.1 278 PVLNESLRMYPPLTSGMVREVPTgGAEIAGRFVPGDTLVEIQHWSINHSKENWVDPWSFRPERFMVDVKvakEHSDMLEAVQAFSMGPRNCIGRNLAMT 376
                 ***********************99***************************************999885543334456899***************** PP

                 HHHHHHHHHHHHEEEEESTSTSGGE CS
        p450 421 elklflatlLqnFevelqpetdppp 445
                 e++l+la++L nF+++l +++  + 
  EEA18657.1 377 EMRLILAKILYNFDMKLANGSHSWI 401
                 ****************988876655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (425 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       678  (0.0378158); expected 358.6 (0.02)
Passed bias filter:                      603  (0.0336327); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.43
# Mc/sec: 2968.60
//
Query:       EEA18658.1  [L=488]
Description: cytochrome P450 monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-68  232.1   0.0    2.6e-68  230.9   0.0    1.5  2  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.5     0.093   1.7e+03     275     293 ..      10      28 ..       4      30 .. 0.82
   2 !  230.9   0.0   1.4e-72   2.6e-68      26     439 ..      58     460 ..      33     482 .. 0.88

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.093
                 HHHHHHHHHHHHHHHHHSH CS
        p450 275 vdTtsstlswaLyeLaknP 293
                 + T    ++w++y+L+ +P
  EEA18658.1  10 STTLLVPITWMIYNLYFHP 28 
                 5577789*********999 PP

  == domain 2  score: 230.9 bits;  conditional E-value: 1.4e-72
                 HHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGH..HHHHHHHHHHHHHHTSHSTT.THHHHHHHH CS
        p450  26 lrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfang..ekwkklRrfltptltsfgkl.sleelveee 121
                 +  ++kkygp++r+ +++ ++    +p+a k ++++++   +g  +e   ++  +++kg+ +  ++g  e +  lRr l   + +  ++ + e+++ ++
  EEA18658.1  58 VLPMHKKYGPVVRIAPNELSF---QTPQAWKDIYGHRTGTAAGA-EEMDKYHTFYRTKGEVLSISSGgrEYHGILRRQLAYGFSDR-AMrEQEPIIGSY 151
                 5668***********998776...5799*********9999997.77777777889999999999998777788999999999999.777********* PP

                 HHHHHHHHHCCCCHCS.EEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCCCH.HHTCCSCHHHHHHHHHHHHHHH CS
        p450 122 aedlveklrkkagess.elditellskaaldvigsilFgarfdlledeklselvkaveelssllskssvqllllfp.llkylptkllrklkeavkklkd 218
                 ++ l+++l++++  ++  l+++ + +  ++dvig+++Fg++f++le+ +    v+a+++ +++l      ++ +++  l  l+ +  +kl+     + +
  EEA18658.1 152 IDLLIKRLHENCVDPNkMLNMVSWYNWTTFDVIGDLVFGESFGSLENGNYDPWVAAINDSIKFL----GVINGVKHmGLESLFIWVVKKLN---TGRRE 243
                 ***********9999889******************************7777777777776666....45666666558889999999999...5799* PP

                 HHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHCCTTTT-HHHH CS
        p450 219 lldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklreEidevlgdkreptydd 317
                 ++d+l+++ ++ ++    +r d++  ll++k   ++  +ls ++l a+   +l+aG++Tt++ ls + y L+++Pe+ +k+++E+++++++++e+t   
  EEA18658.1 244 HTDRLVKKLQKRINLG-VERLDLIEGLLQKK---DEW-NLSIHHLEANGSSILIAGSETTATMLSGVTYMLLTHPEALRKVTKEVRTTFKSSEEITLTS 337
                 ****************.68***********7...554.8************************************************************ PP

                 CCT-HHHHHHHHHHHHHSCSSTTEEEEESSS.CEEETTEEE-TT-EEEEEHHHHHT-TTTSSSTTS--GGGGB-TTSCTESSCTT.--TTEEGGGS-TT CS
        p450 318 lqklpyldavikEtLRlhpvvplllpRevtk.dvvirgylipkGtevivnlyalhrdpevfpnPeeFdpeRFldekgnskrksfa.flPFGaGpRnCiG 414
                 +++l+y+ a+++E+LR +p+vp+++pR+v+k   +i g  +p++t+v ++++a  ++++++ +P  ++peR+l +   +  + fa + PF+ GpRnCiG
  EEA18658.1 338 VSSLTYMLACLNESLRAYPPVPFGMPRQVPKgGATIAGEYVPEDTVVAIWHWAAYHNDQLWTDPFGYHPERYLHDPR-FANDAFAiHNPFSHGPRNCIG 435
                 *******************************99******************************************99.5555555278*********** PP

                 HHHHHHHHHHHHHHHHHHEEEEEST CS
        p450 415 erlArmelklflatlLqnFevelqp 439
                 ++lA+ e++l+la+lL  Fe+ l +
  EEA18658.1 436 RHLAYAEMRLVLARLLFDFEMRLAD 460
                 ********************99854 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (488 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       498  (0.0277762); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 3133.11
//
Query:       EEA18659.1  [L=187]
Description: DUF962 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.5e-26   91.1   0.0    6.6e-26   90.2   0.0    1.4  1  DUF962    Protein of unknown function (DUF962)


Domain annotation for each model (and alignments):
>> DUF962  Protein of unknown function (DUF962)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.2   0.0   3.7e-30   6.6e-26       3      93 ..       5     158 ..       3     160 .. 0.98

  Alignments for each domain:
  == domain 1  score: 90.2 bits;  conditional E-value: 3.7e-30
      DUF962   3 sleefyafYlaeHsnpinrllHfigvplilltvlllllrak.......................................................... 43 
                 +le+++ fY+++H+np+n+++H+i+vp+il+t + l+ +++                                                          
  EEA18659.1   5 DLERQLVFYGTYHHNPVNVRIHMIFVPVILITSIQLFTNTPtliplpdflqykylplnagtiqsliyalgyillepvvglicvptllgaaaymnyltmt 103
                 6899*********************************************************************************************** PP

      DUF962  44 .....lklllalfvvgyifafvGHfvfEkrkPAlfknplqsllidplmvllellg 93 
                       ++ + +f+v +i++f+GH+ +E+r+PAl++n++q+l+++pl+v+le l+
  EEA18659.1 104 ygataTSWSFGIFIVSWIAQFIGHGAYEGRSPALLDNLFQALFLAPLFVFLEYLF 158
                 ****99********************************************99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (187 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       531  (0.0296168); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1239.64
//
Query:       EEA18660.1  [L=172]
Description: DUF962 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.2e-10   39.0   0.5    1.9e-09   37.5   0.5    1.7  1  DUF962    Protein of unknown function (DUF962)


Domain annotation for each model (and alignments):
>> DUF962  Protein of unknown function (DUF962)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.5   0.5   1.1e-13   1.9e-09       3      44 ..       5     106 ..       3     129 .. 0.77

  Alignments for each domain:
  == domain 1  score: 37.5 bits;  conditional E-value: 1.1e-13
      DUF962   3 sleefyafYlaeHsnpinrllHfigvplilltvlllllrak.......................................................... 43 
                 +le+++ fY+++H+np+n+++H+i+vp+il+t + l+ +++                                                          
  EEA18660.1   5 DLERQLVFYGTYHHNPVNVRIHMIFVPVILITSIQLFTNTPtliplpdflqykylplnagtiqsliyalgyillepvvglicvptllgaaaymnyltmt 103
                 6899**********************************9999999999999999999998888888887777777766666666666666666655555 PP

      DUF962  44 ..l 44 
                   +
  EEA18660.1 104 ygA 106
                 540 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (172 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       613  (0.0341904); expected 358.6 (0.02)
Passed bias filter:                      302  (0.0168442); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1208.99
//
Query:       EEA18661.1  [L=187]
Description: DUF962 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.5e-26   91.1   0.0    6.6e-26   90.2   0.0    1.4  1  DUF962    Protein of unknown function (DUF962)


Domain annotation for each model (and alignments):
>> DUF962  Protein of unknown function (DUF962)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.2   0.0   3.7e-30   6.6e-26       3      93 ..       5     158 ..       3     160 .. 0.98

  Alignments for each domain:
  == domain 1  score: 90.2 bits;  conditional E-value: 3.7e-30
      DUF962   3 sleefyafYlaeHsnpinrllHfigvplilltvlllllrak.......................................................... 43 
                 +le+++ fY+++H+np+n+++H+i+vp+il+t + l+ +++                                                          
  EEA18661.1   5 DLERQLVFYGTYHHNPVNVRIHMIFVPVILITSIQLFTNTPtliplpdflqykylplnagtiqsliyalgyillepvvglicvptllgaaaymnyltmt 103
                 6899*********************************************************************************************** PP

      DUF962  44 .....lklllalfvvgyifafvGHfvfEkrkPAlfknplqsllidplmvllellg 93 
                       ++ + +f+v +i++f+GH+ +E+r+PAl++n++q+l+++pl+v+le l+
  EEA18661.1 104 ygataTSWSFGIFIVSWIAQFIGHGAYEGRSPALLDNLFQALFLAPLFVFLEYLF 158
                 ****99********************************************99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (187 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       531  (0.0296168); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.26s 00:00:00.67 Elapsed: 00:00:00.40
# Mc/sec: 1402.65
//
Query:       EEA18662.1  [L=161]
Description: DUF962 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-15   56.9   0.0      3e-15   56.1   0.0    1.5  1  DUF962    Protein of unknown function (DUF962)


Domain annotation for each model (and alignments):
>> DUF962  Protein of unknown function (DUF962)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.1   0.0   1.7e-19     3e-15      26      93 ..       2     132 ..       1     134 [. 0.87

  Alignments for each domain:
  == domain 1  score: 56.1 bits;  conditional E-value: 1.7e-19
      DUF962  26 igvplilltvlllllrak...............................................................lklllalfvvgyifafvG 61 
                 i+vp+il+t + l+ +++                                                                ++ + +f+v +i++f+G
  EEA18662.1   2 IFVPVILITSIQLFTNTPtliplpdflqykylplnagtiqsliyalgyillepvvglicvptllgaaaymnyltmtygataTSWSFGIFIVSWIAQFIG 100
                 78888888888888888888888888888888888888888888888888888888888888888888888888899999899**************** PP

      DUF962  62 HfvfEkrkPAlfknplqsllidplmvllellg 93 
                 H+ +E+r+PAl++n++q+l+++pl+v+le l+
  EEA18662.1 101 HGAYEGRSPALLDNLFQALFLAPLFVFLEYLF 132
                 ***************************99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (161 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       626  (0.0349155); expected 358.6 (0.02)
Passed bias filter:                      385  (0.0214736); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1180.51
//
Query:       EEA18663.1  [L=169]
Description: RNA polymerase II subunit 7 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.2e-15   56.8   0.0    4.3e-15   55.8   0.0    1.5  1  SHS2_Rpb7-N  SHS2 domain found in N terminus of Rpb7p/Rpc25p/
    2.4e-09   37.4   0.0    3.7e-09   36.8   0.0    1.2  1  S1           S1 RNA binding domain


Domain annotation for each model (and alignments):
>> SHS2_Rpb7-N  SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.8   0.0   4.8e-19   4.3e-15       2      70 .]       9      76 ..       8      76 .. 0.98

  Alignments for each domain:
  == domain 1  score: 55.8 bits;  conditional E-value: 4.8e-19
                 EEEEE-GGGTTSTHHHHHHHHHHHHHTTBEETTTEEEEEEEEEEEECCEEE-TTTSSEEEEEEEEEEEE CS
  SHS2_Rpb7-N  2 dtvrlePsylgstledallerllekyegkvvpslGvivavldiaeysegkvlggsGsvyvrVtfralvF 70
                 ++v l+Ps++g++++++l  rl+e  eg++  +  ++++v d  ++++g+v++gsG++ +++++ra+++
   EEA18663.1  9 KVVTLHPSFFGPNVKEYLINRLNEEEEGRCTGDH-FVICVMDMVDIGDGRVIPGSGHAEYTIKYRAIIW 76
                 69*******************************7.********************************98 PP

>> S1  S1 RNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.8   0.0   4.2e-13   3.7e-09       1      69 [.      77     154 ..      77     158 .. 0.96

  Alignments for each domain:
  == domain 1  score: 36.8 bits;  conditional E-value: 4.2e-13
                 HSTTTCEEEEEEEEEETTEEEEEETTTEEEEEEGGGSSSS..........CEESCHHHCEETTEEEEEEEEEEETTTTE CS
          S1   1 kpekgevveGeVtsvtkgGafVelgngvegfvpaselsrd..........arvedpdevlkvGdevkvkvlkvdkdrrr 69 
                 kp+ ge v+++Vtsv + G+f   g + ++f+ ++++++d            +++ d+v+  G  +++k+l+v+ d   
  EEA18663.1  77 KPFRGETVDAIVTSVKPTGIFTLAG-PLSVFIARKNIPSDikwepgtvppQYTDHADQVIERGTSLRLKILGVKPDVSA 154
                 7999*********************.************************99*********************999775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (169 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       202  (0.0112667); expected 358.6 (0.02)
Passed bias filter:                      198  (0.0110436); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.41u 0.25s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 1204.06
//
Query:       EEA18664.1  [L=531]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (531 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       539  (0.030063); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.57u 0.25s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 3605.86
//
Query:       EEA18665.1  [L=1038]
Description: eukaryotic translation initiation factor 2C, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-70  236.8   0.0    4.6e-70  236.2   0.0    1.3  1  Piwi      Piwi domain
    4.1e-19   69.6   0.1    2.8e-18   66.9   0.0    2.2  2  ArgoN     N-terminal domain of argonaute
    3.7e-11   42.5   0.0      1e-10   41.1   0.0    1.8  2  ArgoL1    Argonaute linker 1 domain
    4.6e-08   33.3   0.0      2e-07   31.2   0.0    2.1  2  ArgoL2    Argonaute linker 2 domain
  ------ inclusion threshold ------
       0.12   11.6   0.2       0.23   10.7   0.2    1.4  1  DUF4141   Domain of unknown function (DUF4141)


Domain annotation for each model (and alignments):
>> Piwi  Piwi domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  236.2   0.0   1.3e-73   4.6e-70       1     301 [.     689    1000 ..     689    1001 .. 0.93

  Alignments for each domain:
  == domain 1  score: 236.2 bits;  conditional E-value: 1.3e-73
                  EEEEEECSSGHHCHHHHHHHHHHTCCCCEEEEEHHHHCTCCHHHHHHHHHHHHHHHHTT-BS-EEESSSTTSSE.....EEEEEEEEEECCC.SCCC CS
        Piwi    1 lilvilpekkkdkyheikkyletdlgiisqcillktilkrqlkkqtltnvllkinvKlGgknvliveikleldv.sptliiGidishgtagt.vdnp 95  
                  ++lv+lp+ ++  y++ik  ++++ g+   c+ +++  +   ++q+ +nv+lk+n+Kl g+n  +   +l l    +t+ +Gid++h++ g  ++ p
  EEA18665.1  689 FVLVVLPRRETFLYNTIKYLCDVKYGLLHACVVADKFARG--GPQYDANVALKVNLKLNGTNHIVGGTQLGLISkGKTMLVGIDVTHPSPGSvKNAP 783 
                  589**********************************999..8*******************666666665533689***************8888* PP

                  EEEEEEEEEETSSEEEEEEEEESSCCCCHHHHHHHHHHHHHHHHHHTTTT-TTSEEEEEESS....S..S-HHHHHHHHHHHHHHHHHCTTTEEEEE CS
        Piwi   96 svaavvasldkensrylaevstqassqelleklkeiikellrefkksskkkkperiivyRdGvseGqfkqvlnsEvkelkealkklkeqyqpkltvi 192 
                  s+aa+vas+ k+ s++ a+  +q  +qe ++ l+  +k  l+ +   +++  pe+iivyRdGvseGq+  v+ +E+++lk+a++++  + qp++  +
  EEA18665.1  784 SIAAIVASVGKDLSQFPAQLHVQPGKQEQVDALDVLLKSRLKIWHDIHEE-YPENIIVYRDGVSEGQYDMVVTKELPQLKKACRDMCGKKQPRISIV 879 
                  *************************************************9.********************************************** PP

                  EEECSCS--EEESESTC..CCEETTTCEEETTEEEEEEEECCEEECCCCEEEEEEEEEEEEEEES............S-CCHHHHHHHHHCTGGTTT CS
        Piwi  193 vvqkrhhtrfFasdkae..ksqnippGtvvdkkitlpeekdfylcshaglqgtvkPtkytvlvdea..........klsadelqsltyklchmyqrs 277 
                  vv krhhtrf++  +++  ks+n+p+Gtvvd  +t++  +df+l sha lqgt++P++y v++de+            sa+ l +l + lc+++ r+
  EEA18665.1  880 VVGKRHHTRFYVTREQDasKSKNPPNGTVVDRGVTEARAFDFFLQSHAALQGTARPAHYIVVHDEIfagmpinapfTNSAEVLIDLSHRLCYTFGRA 976 
                  ************9988888**********************************************744333333223478999************** PP

                  TSS-SS-HHHHHHHHHHHHHHTCC CS
        Piwi  278 trsvsiPapvyyAhklAkrvrnnl 301 
                  t++vsi +p+yyA+++ +r+r++l
  EEA18665.1  977 TKAVSICPPAYYADLVCERARCYL 1000
                  ********************9875 PP

>> ArgoN  N-terminal domain of argonaute
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.9   0.0   7.9e-22   2.8e-18       2     138 .]     152     297 ..     151     297 .. 0.73
   2 ?   -0.3   0.0      0.42   1.5e+03      38      79 ..     825     870 ..     794     932 .. 0.69

  Alignments for each domain:
  == domain 1  score: 66.9 bits;  conditional E-value: 7.9e-22
       ArgoN   2 piklraNyFkvtslpdktlyhYdveit....kkakrvg.lrriiellleeykkselagkkpayDgrknlysakkLp........kefe.dlpaaeesak 86 
                 +i l+aNy  +t++ + ++y+Y+ +i+    kk+ +++  +r+++lllee++++e  + ++a+D r+n++s+kkL+         +f    +aa+e+  
  EEA18665.1 152 EILLYANYMDLTVKGSAKCYRYSIDIGpgpdKKVPSIKrCKRLVQLLLEEHFAAE--RGHIATDSRANMVSSKKLDkipdgvesTDFRvRWKAANET-- 246
                 799*********888889*****999877753335666789*******8877555..445999************7666664333333222213333.. PP

       ArgoN  87 kepsekrrrksrtfkvtikfaksinlqsLleylrgkq....deasleaiqaLdivl 138
                      + + +++++ vt+kf++ i +++L +yl +        ++ e++qaL+iv+
  EEA18665.1 247 -----EYETDADVHIVTVKFTGMIAMSDLIDYLTSSDasafFASKSEILQALNIVV 297
                 .....33345569********99**********42222345556666*******95 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.42
       ArgoN  38 riiellleeykkselagkkpayDgrknlysakkLp..kefe.dl.p 79 
                 +i   ++eey ++++  ++ +  g+  ++ +k+Lp  k+   d+  
  EEA18665.1 825 KIWHDIHEEYPENIIVYRDGVSEGQYDMVVTKELPqlKKACrDMcG 870
                 4666677778788888889999999999999999666333234442 PP

>> ArgoL1  Argonaute linker 1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.1   0.0   2.8e-14     1e-10       2      52 .]     312     362 ..     311     362 .. 0.92
   2 ?   -4.0   0.0       3.5   1.3e+04      37      47 ..     763     773 ..     761     773 .. 0.82

  Alignments for each domain:
  == domain 1  score: 41.1 bits;  conditional E-value: 2.8e-14
      ArgoL1   2 vgrsFfspp.skqrvdLggggleawrGfyqSvRptqggLllNvDvsntaFyk 52 
                 ++++F  +p +++ ++L g+gl ++rG++ SvR ++ +Ll+Nv v+n a y+
  EEA18665.1 312 ANKHFPLNPePNDHFSL-GEGLKVIRGYFVSVRAVTARLLVNVQVKNVAVYE 362
                 689999999888889**.77****************************9995 PP

  == domain 2  score: -4.0 bits;  conditional E-value: 3.5
      ArgoL1  37 ggLllNvDvsn 47 
                 + +l+ +Dv++
  EEA18665.1 763 KTMLVGIDVTH 773
                 468999***98 PP

>> ArgoL2  Argonaute linker 2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.2   0.0   5.6e-11     2e-07       1      47 []     531     580 ..     531     580 .. 0.88
   2 ?   -2.3   0.0       1.6   5.8e+03      20      35 ..     646     660 ..     638     662 .. 0.72

  Alignments for each domain:
  == domain 1  score: 31.2 bits;  conditional E-value: 5.6e-11
      ArgoL2   1 eRkksIle.gvkvlgydd..dpylrafGisidpqmttVpGRvLppPtlkY 47 
                 ++++sI + g+ +lg+++  +++l++fG++  p+++tVpGR L++P + Y
  EEA18665.1 531 DNADSIINqGAPLLGFSPttNNVLKSFGLEPIPNLITVPGRTLQAPLITY 580
                 589999999*******55325888**********************9988 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1.6
      ArgoL2  20 ylrafGisidpqmttV 35 
                  +ra+G+ id++  tV
  EEA18665.1 646 NVRAAGVAIDTK-STV 660
                 4699******74.444 PP

>> DUF4141  Domain of unknown function (DUF4141)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.2   6.4e-05      0.23      18      53 .]     519     557 ..     510     557 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 6.4e-05
     DUF4141  18 AQ...WVVtDPgNLAqgIvNsakeivqtSkTasntlknF 53 
                 AQ   ++V  Pg  A +I+N+   +   S T +n+lk+F
  EEA18665.1 519 AQmisFAVRSPGDNADSIINQGAPLLGFSPTTNNVLKSF 557
                 5544478999****************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1038 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       483  (0.0269396); expected 358.6 (0.02)
Passed bias filter:                      408  (0.0227564); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.77u 0.30s 00:00:01.07 Elapsed: 00:00:00.46
# Mc/sec: 6854.33
//
Query:       EEA18666.1  [L=859]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.2e-12   46.6   0.0      5e-12   45.4   0.0    1.6  1  Fungal_trans  Fungal specific transcription factor domain
    8.1e-08   32.3  12.4    1.3e-07   31.6  12.4    1.3  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.016   15.1   0.2      0.035   14.0   0.2    1.6  1  HSBP1         Heat shock factor binding protein 1


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.4   0.0   8.4e-16     5e-12       3     204 ..     241     442 ..     239     471 .. 0.78

  Alignments for each domain:
  == domain 1  score: 45.4 bits;  conditional E-value: 8.4e-16
  Fungal_trans   3 rffsn.fh.pqfpilhkpsflpktssenssksayasp..llllailalGalfsesetkesnssltses....qefiafplraeili...hedfssps 88 
                   rff n  h p  ++lh psf ++++ + + +sa+++   ++l+a++ l++l+ + +  e+ ++++ +s         +  r+ +++   ++d+++p 
    EEA18666.1 241 RFFNNrGHgPGAYVLHVPSFQKDYNEHWKDPSASCPVwiGMLYAMMRLAMLSYYHDG-EEPPEFKGKSldmsK----S-FRHLMCQcliLADYTKPY 331
                   7888875558889***********666667777777622567******998766655.556777777744431....2.244444455578999999 PP

  Fungal_trans  89 sslwilqsL..lllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinl 183
                   +  + +++L   + + ++ t + +  ++ ++g+  rla ++g hr+++        + ++++ e+rrR+w +    D ++++++G p++l+  ++++
    EEA18666.1 332 P--YLIETLvlHMHADFSETKEANVRVWILCGIIARLAMRMGYHRDSKMFP-----NITPFQGEMRRRVWAYLGQADLLFSFQVGMPSMLRPGDTDT 421
                   9..77885511556788888888888888********************99.....5**************************************** PP

  Fungal_trans 184 pLPcddddlwesddaseetlv 204
                   +LP +  d+++  d  e+   
    EEA18666.1 422 ELPRNLFDEDFGPDSKEIPPA 442
                   *******9*999988776555 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.6  12.4   2.2e-11   1.3e-07       2      36 ..      33      67 ..      32      72 .. 0.88

  Alignments for each domain:
  == domain 1  score: 31.6 bits;  conditional E-value: 2.2e-11
                S-HHHHHCT---STSSSS-HHHHHCT..HHHCCCCTC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkkln..leCtfyses 36
                +C +Cr++K KC++ +P C nC+k++  + Ct y ++
  EEA18666.1 33 SCAPCRQRKLKCNRSHP-CENCIKRGdaSSCT-YAQP 67
                8****************.**************.6655 PP

>> HSBP1  Heat shock factor binding protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.2   5.9e-06     0.035      30      49 ..      83     102 ..      82     104 .. 0.95

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 5.9e-06
       HSBP1  30 DdMssriDdLEksiadlmtq 49 
                 DdM++riD LE+ + +lmt+
  EEA18666.1  83 DDMQNRIDRLENLVLSLMTN 102
                 9*****************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (859 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       939  (0.0523733); expected 358.6 (0.02)
Passed bias filter:                      673  (0.037537); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.74u 0.29s 00:00:01.03 Elapsed: 00:00:00.45
# Mc/sec: 5695.27
//
Query:       EEA18667.1  [L=308]
Description: nucleic acid-binding protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.1e-34  118.0   0.1    1.5e-18   66.4   0.1    2.4  2  RRM_1      RNA recognition motif. (a.k.a. RRM, RBD, or RNP do
     0.0013   18.8   0.1       0.38   10.9   0.1    3.1  3  RRM_7      RNA recognition motif
  ------ inclusion threshold ------
      0.045   13.4   0.0        0.1   12.3   0.0    1.5  1  SET_assoc  Histone lysine methyltransferase SET associated


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.4   0.1   2.4e-22   1.5e-18       1      69 [.     112     180 ..     112     181 .. 0.98
   2 !   49.4   0.0   4.9e-17   2.9e-13       1      70 []     203     273 ..     203     273 .. 0.97

  Alignments for each domain:
  == domain 1  score: 66.4 bits;  conditional E-value: 2.4e-22
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkklggrel 69 
                 +++gnL +d+t e+Lk  ++ fG ++++ +++d++g skgf++V+F+s e+A++A+e++n + ++gr++
  EEA18667.1 112 IYIGNLFFDITAEDLKSKMESFGVVEKAAIISDARGLSKGFGYVTFDSVEAAQRAIEEMNQQVYEGRRV 180
                 8*****************************************************************986 PP

  == domain 2  score: 49.4 bits;  conditional E-value: 4.9e-17
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrelk 70 
                 l++gnL++d+t++eL elF+ +  + ++++  d +tg+++gfa  +F +  +A++Ale l  k  +gr+lk
  EEA18667.1 203 LYIGNLAYDLTDRELNELFKSVRNVIEVRVAVDrQTGNPRGFAHADFLDTPSAQAALEILSSKAPHGRRLK 273
                 8***********************************************************99999999885 PP

>> RRM_7  RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.9   0.1   6.3e-05      0.38       1      74 [.     109     174 ..     109     193 .. 0.74
   2 !    4.3   0.0    0.0075        45       2      26 ..     201     225 ..     200     248 .. 0.84
   3 ?   -2.6   0.0         1   6.2e+03      28      44 ..     272     288 ..     260     296 .. 0.66

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 6.3e-05
       RRM_7   1 srkvFvGGlPiDiteeelkatfkefgkvlvdwPkkaeskkkaaenskaakgyvflvfedeksvkaLleacteee 74 
                 s  +++G l  Dit e+lk+ +++fg v      ka      ++++   kg+ ++ f++ ++ ++ +e+ +++ 
  EEA18667.1 109 SPTIYIGNLFFDITAEDLKSKMESFGVVE-----KAAI---ISDARGLSKGFGYVTFDSVEAAQRAIEEMNQQV 174
                 5679**********************763.....3222...223334567999999999999888888877765 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.0075
       RRM_7   2 rkvFvGGlPiDiteeelkatfkefg 26 
                 r +++G l  D+t++el++ fk+  
  EEA18667.1 201 RSLYIGNLAYDLTDRELNELFKSVR 225
                 6689***************999765 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 1
       RRM_7  28 vlvdwPkkaeskkkaae 44 
                 ++vd+ ++++ +++++ 
  EEA18667.1 272 LKVDFSQNPKRTQRRNA 288
                 67888888666665543 PP

>> SET_assoc  Histone lysine methyltransferase SET associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   1.7e-05       0.1      11      56 ..     120     173 ..     118     179 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.7e-05
   SET_assoc  11 kvtvedlkkrLkkyew...eriledktGy.....YivFndskeAerCfraedgt 56 
                 ++t+edlk +++++++   + i++d  G      Y++F++ + A+r+ ++++++
  EEA18667.1 120 DITAEDLKSKMESFGVvekAAIISDARGLskgfgYVTFDSVEAAQRAIEEMNQQ 173
                 5899**********9833356****988666669****************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (308 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1057  (0.0589548); expected 358.6 (0.02)
Passed bias filter:                      525  (0.0292822); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.47
# Mc/sec: 1978.23
//
Query:       EEA18668.1  [L=663]
Description: peroxisomal targeting signal-1 receptor (PEX5), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-23   81.3   5.4    2.8e-09   36.4   0.0    5.8  6  TPR_1     Tetratricopeptide repeat
    1.2e-22   78.1   5.7    1.5e-07   31.0   0.0    5.9  5  TPR_2     Tetratricopeptide repeat
    3.4e-17   61.8   5.9    1.9e-08   33.8   0.1    4.8  5  TPR_11    TPR repeat
    5.3e-17   62.2   3.6    1.1e-05   26.0   0.0    4.6  4  TPR_16    Tetratricopeptide repeat
    1.9e-15   56.2   6.6    3.5e-05   24.3   0.0    6.5  6  TPR_14    Tetratricopeptide repeat
    9.6e-15   53.8   3.1     0.0028   17.9   0.1    4.8  4  TPR_17    Tetratricopeptide repeat
    2.2e-13   49.3   3.9    7.5e-07   28.9   0.0    4.1  3  TPR_8     Tetratricopeptide repeat
    7.6e-13   48.8   4.8    0.00023   21.6   0.0    4.5  4  TPR_19    Tetratricopeptide repeat
    4.3e-10   39.8   0.8     0.0055   17.0   0.1    4.3  4  TPR_20    Tetratricopeptide repeat
    1.1e-09   37.6   0.2     0.0072   16.3   0.0    5.6  5  TPR_7     Tetratricopeptide repeat
    1.8e-09   37.8   5.4    0.00012   22.3   0.2    4.5  5  TPR_12    Tetratricopeptide repeat
    1.3e-08   34.9   5.2     0.0042   17.2   0.0    4.2  4  TPR_9     Tetratricopeptide repeat
    2.2e-05   24.6   1.9      0.011   15.9   0.2    2.7  2  ANAPC3    Anaphase-promoting complex, cyclosome, subunit 3
    5.9e-05   23.5   4.0        2.3    9.0   0.0    5.5  5  TPR_6     Tetratricopeptide repeat
    0.00046   19.5   3.2       0.13   11.4   0.5    2.6  3  TPR_15    Tetratricopeptide repeat
     0.0067   16.5   0.2         10    6.2   0.1    4.2  5  MIT       MIT (microtubule interacting and transport) domain
  ------ inclusion threshold ------
      0.013   15.4   0.0      0.032   14.1   0.0    1.7  1  DUF1641   Protein of unknown function (DUF1641)
      0.019   14.8   5.7      0.086   12.7   0.3    3.7  3  TPR_10    Tetratricopeptide repeat
        0.1   12.6   0.4        4.4    7.4   0.0    3.0  3  TPR_3     Tetratricopeptide repeat
        0.2   11.2   5.2        2.7    7.5   1.0    2.7  2  DUF533    Protein of unknown function (DUF533)
       0.76    9.8  11.6        1.9    8.5   8.8    2.9  2  DUF4192   Domain of unknown function (DUF4192)


Domain annotation for each model (and alignments):
>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0       0.4   3.4e+02      15      34 .]     351     370 ..     349     370 .. 0.91
   2 !   20.9   0.1   2.6e-07   0.00023       2      34 .]     372     404 ..     371     404 .. 0.97
   3 ?   -2.1   0.0       4.6   3.9e+03       2      15 ..     406     419 ..     406     419 .. 0.85
   4 !   10.8   0.0   0.00041      0.35       5      28 ..     486     509 ..     482     510 .. 0.90
   5 !   36.4   0.0   3.3e-12   2.8e-09       3      34 .]     526     557 ..     524     557 .. 0.96
   6 !    9.1   0.1    0.0013       1.1       2      23 ..     559     580 ..     558     586 .. 0.92

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.4
                 T-HHHHHHHHHHHHHHSTTH CS
       TPR_1  15 gkydeAleyyekALelnPnn 34 
                 g++  A  ++e A++ +P++
  EEA18668.1 351 GNLSLAALAFEAAVQKDPQH 370
                 78899999**********86 PP

  == domain 2  score: 20.9 bits;  conditional E-value: 2.6e-07
                 HHHHHHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1   2 kalynlGnayfklgkydeAleyyekALelnPnn 34 
                 +a+  lG a  +++k + Al + e+AL+l+Pnn
  EEA18668.1 372 QAWTMLGSAQAQNEKENPALRALEQALKLDPNN 404
                 79******************************8 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 4.6
                 HHHHHHHHHHHHTT CS
       TPR_1   2 kalynlGnayfklg 15 
                 +al +l++ y + g
  EEA18668.1 406 DALMGLAVSYTNEG 419
                 6999******8866 PP

  == domain 4  score: 10.8 bits;  conditional E-value: 0.00041
                 HHHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_1   5 ynlGnayfklgkydeAleyyekAL 28 
                  +lG++++  ++y +A+++++ AL
  EEA18668.1 486 VGLGVLFYCAEEYGKAVDCFSAAL 509
                 689*******************99 PP

  == domain 5  score: 36.4 bits;  conditional E-value: 3.3e-12
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1   3 alynlGnayfklgkydeAleyyekALelnPnn 34 
                  +++lG+++ + g+ +eA+e+yekAL++nPn+
  EEA18668.1 526 LWNRLGATLANSGRSEEAIEAYEKALTINPNF 557
                 6*****************************97 PP

  == domain 6  score: 9.1 bits;  conditional E-value: 0.0013
                 HHHHHHHHHHHHTT-HHHHHHH CS
       TPR_1   2 kalynlGnayfklgkydeAley 23 
                 +a ynlG+ + + g y eA ++
  EEA18668.1 559 RARYNLGVSCINIGCYPEAAQH 580
                 799****************998 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.0      0.02        17      14      34 .]     350     370 ..     345     370 .. 0.88
   2 !   18.1   0.1   2.3e-06    0.0019       2      34 .]     372     404 ..     371     404 .. 0.96
   3 !   10.6   0.0    0.0006      0.51       4      29 ..     485     510 ..     482     513 .. 0.89
   4 !   31.0   0.0   1.7e-10   1.5e-07       3      33 ..     526     556 ..     524     557 .. 0.95
   5 !   10.5   0.0   0.00063      0.53       2      29 ..     559     586 ..     558     589 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.02
       TPR_2  14 lgdyeeAleafekAleldPnn 34 
                  g++  A+ afe+A++ dP++
  EEA18668.1 350 GGNLSLAALAFEAAVQKDPQH 370
                 599999*************86 PP

  == domain 2  score: 18.1 bits;  conditional E-value: 2.3e-06
       TPR_2   2 ealynlGlayyklgdyeeAleafekAleldPnn 34 
                 +a+ +lG a +++ + + Al+a+e+Al+ldPnn
  EEA18668.1 372 QAWTMLGSAQAQNEKENPALRALEQALKLDPNN 404
                 699*****************************8 PP

  == domain 3  score: 10.6 bits;  conditional E-value: 0.0006
       TPR_2   4 lynlGlayyklgdyeeAleafekAle 29 
                    lG + y + +y +A+++f +Al+
  EEA18668.1 485 QVGLGVLFYCAEEYGKAVDCFSAALA 510
                 5679********************97 PP

  == domain 4  score: 31.0 bits;  conditional E-value: 1.7e-10
       TPR_2   3 alynlGlayyklgdyeeAleafekAleldPn 33 
                 ++++lG  ++++g+ eeA+ea+ekAl ++Pn
  EEA18668.1 526 LWNRLGATLANSGRSEEAIEAYEKALTINPN 556
                 7*****************************9 PP

  == domain 5  score: 10.5 bits;  conditional E-value: 0.00063
       TPR_2   2 ealynlGlayyklgdyeeAleafekAle 29 
                 +a ynlG ++++ g y eA++++  Al+
  EEA18668.1 559 RARYNLGVSCINIGCYPEAAQHLLGALA 586
                 578*******************998886 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.5   0.0   0.00089      0.76       6      41 ..     349     384 ..     347     385 .. 0.94
   2 !   17.1   0.1   3.8e-06    0.0033      13      39 ..     390     416 ..     388     419 .. 0.91
   3 ?   -1.7   0.0       2.8   2.4e+03      26      39 ..     480     493 ..     469     495 .. 0.81
   4 ?    0.1   0.0      0.78   6.7e+02       7      22 ..     495     510 ..     489     514 .. 0.81
   5 !   33.8   0.1   2.2e-11   1.9e-08       7      36 ..     537     566 ..     531     572 .. 0.91

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00089
      TPR_11   6 eqGkyeeAieaYkkAlkldPdnaeayynLGlayykq 41 
                 e G++  A  a+++A++ dP+ + a+  LG a++++
  EEA18668.1 349 EGGNLSLAALAFEAAVQKDPQHVQAWTMLGSAQAQN 384
                 5799999*************************9986 PP

  == domain 2  score: 17.1 bits;  conditional E-value: 3.8e-06
      TPR_11  13 AieaYkkAlkldPdnaeayynLGlayy 39 
                 A+ a+++AlkldP+n +a+ +L++ y 
  EEA18668.1 390 ALRALEQALKLDPNNLDALMGLAVSYT 416
                 899********************9985 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 2.8
      TPR_11  26 dnaeayynLGlayy 39 
                  ++++  +LG+++y
  EEA18668.1 480 MDPDVQVGLGVLFY 493
                 58999999999987 PP

  == domain 4  score: 0.1 bits;  conditional E-value: 0.78
      TPR_11   7 qGkyeeAieaYkkAlk 22 
                   +y +A+ ++++Al+
  EEA18668.1 495 AEEYGKAVDCFSAALA 510
                 57899*******9997 PP

  == domain 5  score: 33.8 bits;  conditional E-value: 2.2e-11
      TPR_11   7 qGkyeeAieaYkkAlkldPdnaeayynLGl 36 
                  G+ eeAieaY+kAl ++P++++a ynLG+
  EEA18668.1 537 SGRSEEAIEAYEKALTINPNFVRARYNLGV 566
                 7999*************************7 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.3   1.1e-05     0.009      10      47 ..     350     384 ..     348     389 .. 0.92
   2 !   14.8   0.1   3.9e-05     0.034      16      47 ..     390     418 ..     388     421 .. 0.93
   3 ?    1.6   0.0      0.51   4.4e+02      33      62 ..     481     510 ..     466     516 .. 0.61
   4 !   26.0   0.0   1.3e-08   1.1e-05       3      62 ..     530     586 ..     528     589 .. 0.93

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 1.1e-05
      TPR_16  10 agdyddAaaaleaalkrdpssPdaaeAllllgdaalrq 47 
                  g+   Aa a+eaa+ +d   P++++A+  lg a +++
  EEA18668.1 350 GGNLSLAALAFEAAVQKD---PQHVQAWTMLGSAQAQN 384
                 589999************...*************9987 PP

  == domain 2  score: 14.8 bits;  conditional E-value: 3.9e-05
      TPR_16  16 AaaaleaalkrdpssPdaaeAllllgdaalrq 47 
                 A++ale+alk+d   P + +Al++l++++   
  EEA18668.1 390 ALRALEQALKLD---PNNLDALMGLAVSYTNE 418
                 99**********...************99765 PP

  == domain 3  score: 1.6 bits;  conditional E-value: 0.51
      TPR_16  33 aaeAllllgdaalrqgrlaeAaalyraalr 62 
                 +++ + +lg++++ + ++ +A++ + aal+
  EEA18668.1 481 DPDVQVGLGVLFYCAEEYGKAVDCFSAALA 510
                 556666666666666666666666665553 PP

  == domain 4  score: 26.0 bits;  conditional E-value: 1.3e-08
      TPR_16   3 laraalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraalr 62 
                 l+  ++++g+ ++A++a+e al  +   P  ++A+++lg+++   g ++eAa+ ++ al+
  EEA18668.1 530 LGATLANSGRSEEAIEAYEKALTIN---PNFVRARYNLGVSCINIGCYPEAAQHLLGALA 586
                 677899*******************...************************99998875 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.2       5.9   5.1e+03      12      43 ..     272     303 ..     267     304 .. 0.82
   2 !   13.7   0.1    0.0001     0.088      13      42 ..     349     378 ..     344     380 .. 0.89
   3 !   18.6   0.6   2.8e-06    0.0024       3      42 ..     373     412 ..     372     414 .. 0.95
   4 ?    3.6   0.0      0.18   1.5e+02       3      32 ..     407     437 ..     406     447 .. 0.84
   5 ?    2.0   0.0      0.58     5e+02       5      29 ..     486     510 ..     482     521 .. 0.84
   6 !   24.3   0.0   4.1e-08   3.5e-05       3      42 ..     526     565 ..     523     567 .. 0.94

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 5.9
      TPR_14  12 lalGdpdeAiallrralalaPddaeawlllaq 43 
                 +++ + + A a   r la++  +++a+l+l++
  EEA18668.1 272 WQSAQAENASATTSRQLADDDFEEVANLHLGD 303
                 67888889999999999988878889999986 PP

  == domain 2  score: 13.7 bits;  conditional E-value: 0.0001
      TPR_14  13 alGdpdeAiallrralalaPddaeawllla 42 
                 + G++  A+ ++++a++++P++ +aw++l+
  EEA18668.1 349 EGGNLSLAALAFEAAVQKDPQHVQAWTMLG 378
                 67999999*********************8 PP

  == domain 3  score: 18.6 bits;  conditional E-value: 2.8e-06
      TPR_14   3 allalaeallalGdpdeAiallrralalaPddaeawllla 42 
                 a+ +l++a +++++   A+++l++al+l+P++++a++ la
  EEA18668.1 373 AWTMLGSAQAQNEKENPALRALEQALKLDPNNLDALMGLA 412
                 899*********************************9998 PP

  == domain 4  score: 3.6 bits;  conditional E-value: 0.18
      TPR_14   3 allalaeallalGdpdeAiallrrala.laP 32 
                 al+ la  + + G   +A + l+r+l+ ++P
  EEA18668.1 407 ALMGLAVSYTNEGYDSTAYRTLERWLSvKYP 437
                 78889999******************95455 PP

  == domain 5  score: 2.0 bits;  conditional E-value: 0.58
      TPR_14   5 lalaeallalGdpdeAiallrrala 29 
                   l+ +++ ++++ +A++++ +ala
  EEA18668.1 486 VGLGVLFYCAEEYGKAVDCFSAALA 510
                 56777889999************98 PP

  == domain 6  score: 24.3 bits;  conditional E-value: 4.1e-08
      TPR_14   3 allalaeallalGdpdeAiallrralalaPddaeawllla 42 
                 ++ +l++ l+++G+ +eAi+++++al  +P++ +a++ l+
  EEA18668.1 526 LWNRLGATLANSGRSEEAIEAYEKALTINPNFVRARYNLG 565
                 6889********************************9997 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.9   0.0   0.00028      0.24       2      27 ..     360     385 ..     359     390 .. 0.90
   2 !   12.1   0.1   0.00024      0.21       2      27 ..     394     419 ..     393     424 .. 0.89
   3 !    8.9   0.0    0.0025       2.2      15      34 .]     526     545 ..     524     545 .. 0.93
   4 !   17.9   0.1   3.3e-06    0.0028       1      32 [.     546     577 ..     546     579 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00028
      TPR_17   2 ylkaleldPnnadaynnLAelllknG 27 
                 ++ a+++dP ++ a+++L+ ++++n 
  EEA18668.1 360 FEAAVQKDPQHVQAWTMLGSAQAQNE 385
                 899******************99876 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 0.00024
      TPR_17   2 ylkaleldPnnadaynnLAelllknG 27 
                 +++al+ldPnn da+  LA+ + + G
  EEA18668.1 394 LEQALKLDPNNLDALMGLAVSYTNEG 419
                 699****************9997765 PP

  == domain 3  score: 8.9 bits;  conditional E-value: 0.0025
      TPR_17  15 aynnLAelllknGdlmtArq 34 
                 ++n L+ +l++ G++++A++
  EEA18668.1 526 LWNRLGATLANSGRSEEAIE 545
                 7*****************86 PP

  == domain 4  score: 17.9 bits;  conditional E-value: 3.3e-06
      TPR_17   1 lylkaleldPnnadaynnLAelllknGdlmtA 32 
                 +y+kal ++Pn + a +nL++   ++G + +A
  EEA18668.1 546 AYEKALTINPNFVRARYNLGVSCINIGCYPEA 577
                 5********************99999988777 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0   1.7e-06    0.0014       2      34 .]     372     404 ..     371     404 .. 0.96
   2 !   28.9   0.0   8.7e-10   7.5e-07       3      33 ..     526     556 ..     525     557 .. 0.96
   3 ?   -0.9   0.0         3   2.6e+03       2      22 ..     559     579 ..     558     587 .. 0.73

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 1.7e-06
                 CHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH. CS
       TPR_8   2 eayynlgsiylklgdyeeAkeyyekaleldpdn 34 
                 +a+ +lgs+  + ++ + A  ++e+al+ldp+n
  EEA18668.1 372 QAWTMLGSAQAQNEKENPALRALEQALKLDPNN 404
                 89*****************************97 PP

  == domain 2  score: 28.9 bits;  conditional E-value: 8.7e-10
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAkeyyekaleldpd 33 
                 ++++lg ++ + g+ eeA+e+yekal+++p+
  EEA18668.1 526 LWNRLGATLANSGRSEEAIEAYEKALTINPN 556
                 59****************************8 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 3
                 CHHHHHHHHHHHTT-HHHHHH CS
       TPR_8   2 eayynlgsiylklgdyeeAke 22 
                 +a ynlg  +++ g y eA +
  EEA18668.1 559 RARYNLGVSCINIGCYPEAAQ 579
                 7999***99999886666655 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   0.2     0.016        14       5      37 ..     351     383 ..     347     390 .. 0.79
   2 !   18.5   0.2   2.5e-06    0.0022      10      51 ..     390     431 ..     388     438 .. 0.90
   3 ?    0.6   0.0         1   8.5e+02      14      55 ..     467     512 ..     461     524 .. 0.87
   4 !   21.6   0.0   2.7e-07   0.00023       4      50 ..     537     583 ..     534     594 .. 0.90

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.016
      TPR_19   5 gdyaeAlalleqalqedpknaearllLAealla 37 
                 g++  A+ ++e+a q+dp++  a+  L  a+ +
  EEA18668.1 351 GNLSLAALAFEAAVQKDPQHVQAWTMLGSAQAQ 383
                 577779999**********99999999655554 PP

  == domain 2  score: 18.5 bits;  conditional E-value: 2.5e-06
      TPR_19  10 AlalleqalqedpknaearllLAeallalgqldeAealLdal 51 
                 Al++leqal+ dp+n++a+++LA  + + g    A ++L++ 
  EEA18668.1 390 ALRALEQALKLDPNNLDALMGLAVSYTNEGYDSTAYRTLERW 431
                 999***********************9999888888888775 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 1
      TPR_19  14 leqalqedpk....naearllLAeallalgqldeAealLdalpeed 55 
                 + qa q +p     +++++ +L  + + + ++ +A ++ +a+++++
  EEA18668.1 467 FIQAAQLSPSgehmDPDVQVGLGVLFYCAEEYGKAVDCFSAALAST 512
                 567888888888999********************99999998876 PP

  == domain 4  score: 21.6 bits;  conditional E-value: 2.7e-07
      TPR_19   4 egdyaeAlalleqalqedpknaearllLAeallalgqldeAealLda 50 
                 +g+ +eA++++e+al+ +p+  +ar++L   +++ g + eA + L  
  EEA18668.1 537 SGRSEEAIEAYEKALTINPNFVRARYNLGVSCINIGCYPEAAQHLLG 583
                 6899********************************99999987755 PP

>> TPR_20  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.2   0.5    0.0074       6.3      10      45 ..     359     394 ..     352     394 .. 0.93
   2 !   17.0   0.1   6.4e-06    0.0055       3      49 ..     386     432 ..     384     436 .. 0.91
   3 ?   -2.4   0.0       7.2   6.1e+03      21      51 ..     481     511 ..     475     525 .. 0.81
   4 !   15.5   0.0   1.9e-05     0.016       5      66 ..     541     601 ..     537     613 .. 0.84

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0074
      TPR_20  10 eleaalaanpddldarldlAlallaagryeeAleqL 45 
                 ++eaa++++p+ ++a   l  a+++++++  Al +L
  EEA18668.1 359 AFEAAVQKDPQHVQAWTMLGSAQAQNEKENPALRAL 394
                 689*****************************9876 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 6.4e-06
      TPR_20   3 adapelaeleaalaanpddldarldlAlallaagryeeAleqLleil 49 
                 +++p l++le+al+ +p++lda + lA  +  +g    A   L ++l
  EEA18668.1 386 KENPALRALEQALKLDPNNLDALMGLAVSYTNEGYDSTAYRTLERWL 432
                 789***********************************999887666 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 7.2
      TPR_20  21 dldarldlAlallaagryeeAleqLleilkr 51 
                 d d ++ l  + + a++y +A++ + + l++
  EEA18668.1 481 DPDVQVGLGVLFYCAEEYGKAVDCFSAALAS 511
                 8899999999999999999999987776665 PP

  == domain 4  score: 15.5 bits;  conditional E-value: 1.9e-05
      TPR_20   5 apelaeleaalaanpddldarldlAlallaagryeeAleqLleilkrdrkweddaarkqllk 66 
                 ++ +++ e+al+ np+ + ar++l    +  g y eA+++Ll  l+ ++   +++ r++  +
  EEA18668.1 541 EEAIEAYEKALTINPNFVRARYNLGVSCINIGCYPEAAQHLLGALAMHKVV-EQQGREKARE 601
                 57899****************************************988877.5555555555 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0       2.1   1.8e+03      18      34 ..     390     404 ..     375     406 .. 0.85
   2 ?    4.5   0.0      0.05        42       1      28 [.     407     432 ..     407     444 .. 0.89
   3 ?    4.5   0.0     0.049        42       5      31 ..     488     514 ..     486     518 .. 0.82
   4 !   16.3   0.0   8.5e-06    0.0072       2      30 ..     527     553 ..     526     559 .. 0.87
   5 ?    4.5   0.0      0.05        43       3      30 ..     562     589 ..     560     599 .. 0.89

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 2.1
       TPR_7  18 AielyeqsLaltkdped 34 
                 A++ +eq  al  dp++
  EEA18668.1 390 ALRALEQ--ALKLDPNN 404
                 788899*..88888775 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.05
       TPR_7   1 aLlnLarlysrlGdyeeAielyeqsLal 28 
                 aL  La+ y ++G+ ++A + +e+   l
  EEA18668.1 407 ALMGLAVSYTNEGYDSTAYRTLER--WL 432
                 5778*******************9..55 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.049
       TPR_7   5 LarlysrlGdyeeAielyeqsLaltkd 31 
                 L++l+    +y +A++++ ++La t++
  EEA18668.1 488 LGVLFYCAEEYGKAVDCFSAALASTES 514
                 888988889***********7766654 PP

  == domain 4  score: 16.3 bits;  conditional E-value: 8.5e-06
       TPR_7   2 LlnLarlysrlGdyeeAielyeqsLaltk 30 
                 +++L+ +  + G+ eeAie ye+  alt 
  EEA18668.1 527 WNRLGATLANSGRSEEAIEAYEK--ALTI 553
                 799********************..6654 PP

  == domain 5  score: 4.5 bits;  conditional E-value: 0.05
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLaltk 30 
                 +nL++ + + G y eA++++  +La++k
  EEA18668.1 562 YNLGVSCINIGCYPEAAQHLLGALAMHK 589
                 79**********************9995 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   0.2    0.0012         1      29      76 ..     357     402 ..     347     403 .. 0.77
   2 ?    5.6   0.0     0.023        19      48      73 ..     485     510 ..     465     514 .. 0.67
   3 !   22.3   0.2   1.4e-07   0.00012       6      74 ..     485     553 ..     480     556 .. 0.89
   4 !   18.3   0.5   2.5e-06    0.0022       4      74 ..     525     587 ..     522     589 .. 0.82
   5 ?    4.5   0.0     0.049        42       5      34 ..     560     589 ..     556     600 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0012
      TPR_12  29 aleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                 al+   ++   + p+ +++   Lg ++ + ++   Al++le+al++++
  EEA18668.1 357 ALAFEAAV--QKDPQHVQAWTMLGSAQAQNEKENPALRALEQALKLDP 402
                 44444445..456777899999999999****************9875 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.023
      TPR_12  48 lrnLgrlyralgryeeAlelleeala 73 
                 + +Lg l++ +++y +A++ +  ala
  EEA18668.1 485 QVGLGVLFYCAEEYGKAVDCFSAALA 510
                 45667777777777777776666665 PP

  == domain 3  score: 22.3 bits;  conditional E-value: 1.4e-07
      TPR_12   6 lnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealai 74 
                 ++ l+++ + +++y +A +++ +al+  ++    +  ++    + Lg ++  +gr eeA+e++e+al i
  EEA18668.1 485 QVGLGVLFYCAEEYGKAVDCFSAALASTESGTSNQQGQVHLLWNRLGATLANSGRSEEAIEAYEKALTI 553
                 678999**********************87777777788888899**********************98 PP

  == domain 4  score: 18.3 bits;  conditional E-value: 2.5e-06
      TPR_12   4 talnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealai 74 
                  ++n+l+a+l+  gr +eA+e +ekal i      p+    +++++nLg  +   g y eA ++l  ala+
  EEA18668.1 525 LLWNRLGATLANSGRSEEAIEAYEKALTIN-----PN---FVRARYNLGVSCINIGCYPEAAQHLLGALAM 587
                 57888**********************999.....65...4788888888888888888888888877777 PP

  == domain 5  score: 4.5 bits;  conditional E-value: 0.049
      TPR_12   5 alnnlaavlrrlgrydeAlellekaleiar 34 
                 a +nl++ +   g y eA ++l  al++++
  EEA18668.1 560 ARYNLGVSCINIGCYPEAAQHLLGALAMHK 589
                 567999999999999999999999999875 PP

>> TPR_9  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       5.7   4.8e+03      45      60 ..     242     257 ..     240     278 .. 0.81
   2 !   15.2   0.7   2.1e-05     0.018      14      66 ..     356     408 ..     346     412 .. 0.89
   3 ?    0.7   0.0      0.72   6.1e+02      36      60 ..     489     513 ..     483     529 .. 0.83
   4 !   17.2   0.0   4.9e-06    0.0042       2      59 ..     531     588 ..     530     604 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 5.7
       TPR_9  45 lsaAladLeaylalap 60 
                 ++a+l+dL++ ++ +p
  EEA18668.1 242 MEAELNDLDRSVHSTP 257
                 7899999999998887 PP

  == domain 2  score: 15.2 bits;  conditional E-value: 2.1e-05
       TPR_9  14 alavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalapdapdae 66 
                 a  + e  ++ +P++++ +   G ++aq +  + Al++Le++l l+p++ da 
  EEA18668.1 356 AALAFEAAVQKDPQHVQAWTMLGSAQAQNEKENPALRALEQALKLDPNNLDAL 408
                 55567888899************************************998885 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 0.72
       TPR_9  36 GlllaqlGclsaAladLeaylalap 60 
                 G+l +  + + +A++++ a+la ++
  EEA18668.1 489 GVLFYCAEEYGKAVDCFSAALASTE 513
                 788888999999*****99999877 PP

  == domain 4  score: 17.2 bits;  conditional E-value: 4.9e-06
       TPR_9   2 kaiaireedweralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylala 59 
                  a+++++ ++e+a++++e  l ++P+ ++ r+  G+     Gc+ +A++ L  +la+ 
  EEA18668.1 531 GATLANSGRSEEAIEAYEKALTINPNFVRARYNLGVSCINIGCYPEAAQHLLGALAMH 588
                 5789999******************************************998777655 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.5   0.1    0.0056       4.8       8      66 ..     356     415 ..     350     435 .. 0.66
   2 !   15.9   0.2   1.3e-05     0.011      25      80 ..     524     582 ..     488     584 .. 0.79

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0056
                 HHHHHHHHH.HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHH CS
      ANAPC3   8 AiflaerllaaetespedayllAlclylngqykrAyellrka.klnskslgcrylfAqcl 66 
                 A + +e ++++++++ ++  +l+ +  +n++ + A++ l++a kl++++l +++ +A ++
  EEA18668.1 356 AALAFEAAVQKDPQHVQAWTMLGSAQAQNEKENPALRALEQAlKLDPNNLDALMGLAVSY 415
                 555666666666777777777777777777777777777777777777777776666554 PP

  == domain 2  score: 15.9 bits;  conditional E-value: 1.3e-05
                 HHHH..HHHHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHHH- CS
      ANAPC3  25 dayl..lAlclylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaaLe 80 
                 ++++  l+ +l ++g+ ++A+e ++ka  +n++  ++ry ++ +++ ++ y eA ++L 
  EEA18668.1 524 HLLWnrLGATLANSGRSEEAIEAYEKAlTINPNFVRARYNLGVSCINIGCYPEAAQHLL 582
                 3555556889999********************************************97 PP

>> TPR_6  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.0      0.26   2.2e+02       9      32 ..     346     369 ..     343     370 .. 0.89
   2 ?    5.2   0.1     0.045        39       5      32 ..     376     403 ..     372     404 .. 0.82
   3 ?    2.7   0.0      0.29   2.5e+02       1      25 [.     406     430 ..     406     437 .. 0.83
   4 !    9.0   0.0    0.0027       2.3       6      32 ..     530     556 ..     519     556 .. 0.84
   5 ?   -2.1   0.0       9.7   8.3e+03       2      12 ..     560     570 ..     559     586 .. 0.76

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.26
                 HHHHHHHHHHHHHHHHHHHHH-TT CS
       TPR_6   9 syrklgdtdkAlealerlikeYPd 32 
                  ++++g+ + A  a+e  +++ P+
  EEA18668.1 346 IMQEGGNLSLAALAFEAAVQKDPQ 369
                 578899****************98 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.045
                 HHHHHHHHHHHHHHHHHHHHHHHHH-TT CS
       TPR_6   5 klalsyrklgdtdkAlealerlikeYPd 32 
                 +l+ ++ +  +   Al+ale+ +k  P+
  EEA18668.1 376 MLGSAQAQNEKENPALRALEQALKLDPN 403
                 68888888547789***********999 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.29
                 HHHHHHHHHHHHHHHHH.HHHHHHHH CS
       TPR_6   1 dAlyklalsyrklgdtd.kAlealer 25 
                 dAl+ la sy +   +d +A ++ler
  EEA18668.1 406 DALMGLAVSYTNE-GYDsTAYRTLER 430
                 8**********98.444478888876 PP

  == domain 4  score: 9.0 bits;  conditional E-value: 0.0027
                 HHHHHHHHHHHHHHHHHHHHHHHH-TT CS
       TPR_6   6 lalsyrklgdtdkAlealerlikeYPd 32 
                 l+  + + g++++A+ea+e+ ++  P+
  EEA18668.1 530 LGATLANSGRSEEAIEAYEKALTINPN 556
                 555566657*************99997 PP

  == domain 5  score: -2.1 bits;  conditional E-value: 9.7
                 HHHHHHHHHHH CS
       TPR_6   2 Alyklalsyrk 12 
                 A y+l+ s ++
  EEA18668.1 560 ARYNLGVSCIN 570
                 89999999876 PP

>> TPR_15  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.1       7.2   6.2e+03      57      97 ..     258     297 ..     255     303 .. 0.60
   2 !   11.4   0.5   0.00015      0.13     144     207 ..     369     432 ..     352     441 .. 0.82
   3 !    7.8   0.0     0.002       1.7     133     183 ..     509     561 ..     490     585 .. 0.76

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 7.2
      TPR_15  57 lqqedearkAyrqLlasgkaraedyerliellydaepkeaa 97 
                 lq++ e+ +  ++ ++s +a+   + +  +l  d++++e a
  EEA18668.1 258 LQNQSEGFEQFERVWQSAQAENASATTSRQL-ADDDFEEVA 297
                 5666666666666666666666666555555.555555555 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00015
      TPR_15 144 qsaafllaraelyrqegqtdaAlrdyreAlalapdsselraallWlliDlgrraeLrellkawk 207
                 q  + + ++++++ q+ +++ Alr++++Al+l+p++ ++  +l   + + g +  + ++l++w 
  EEA18668.1 369 QHVQAWTMLGSAQAQNEKENPALRALEQALKLDPNNLDALMGLAVSYTNEGYDSTAYRTLERWL 432
                 44467999****************************9999999888888888887888888886 PP

  == domain 3  score: 7.8 bits;  conditional E-value: 0.002
      TPR_15 133 lkslee.eeaae.qsaafllaraelyrqegqtdaAlrdyreAlalapdsselr 183
                 l+s e+ +++ + q  + + ++++   + g++++A+++y++Al+ +p+   +r
  EEA18668.1 509 LASTESgTSNQQgQVHLLWNRLGATLANSGRSEEAIEAYEKALTINPNFVRAR 561
                 5554421222332667889999************************9855555 PP

>> MIT  MIT (microtubule interacting and transport) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       7.8   6.7e+03      30      45 ..     390     404 ..     389     417 .. 0.60
   2 ?   -2.3   0.0       5.8   4.9e+03      44      63 ..     454     473 ..     447     474 .. 0.81
   3 ?    0.8   0.0      0.62   5.3e+02      25      40 ..     496     511 ..     494     522 .. 0.72
   4 ?    6.2   0.1     0.012        10      15      32 ..     535     552 ..     530     553 .. 0.87
   5 ?    3.3   0.0       0.1        90      26      54 ..     573     604 ..     571     606 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 7.8
         MIT  30 alelLlqalkekneer 45 
                 al+ L qalk  +++ 
  EEA18668.1 390 ALRALEQALK-LDPNN 404
                 6777778887.33344 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 5.8
         MIT  44 errellrekieeYleRaeeL 63 
                 ++r+ll+ k++     a +L
  EEA18668.1 454 TDRQLLHDKVTDLFIQAAQL 473
                 57999***999887777776 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.62
         MIT  25 elYkealelLlqalke 40 
                 e Y +a++ ++ al+ 
  EEA18668.1 496 EEYGKAVDCFSAALAS 511
                 5588999999999983 PP

  == domain 4  score: 6.2 bits;  conditional E-value: 0.012
         MIT  15 DnagnyeeAlelYkeale 32 
                  n+g  eeA+e+Y++al 
  EEA18668.1 535 ANSGRSEEAIEAYEKALT 552
                 58999***********85 PP

  == domain 5  score: 3.3 bits;  conditional E-value: 0.1
         MIT  26 lYkealelLlqalk.e..kneerrellrekie 54 
                 +Y ea ++Ll al+     +++ re+ re +e
  EEA18668.1 573 CYPEAAQHLLGALAmHkvVEQQGREKAREIVE 604
                 8*************746878889999999876 PP

>> DUF1641  Protein of unknown function (DUF1641)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   3.7e-05     0.032      20      39 .]     481     500 ..     480     500 .. 0.92

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 3.7e-05
     DUF1641  20 DPDVqrGLGfllalLKalGk 39 
                 DPDVq GLG+l+  +++ Gk
  EEA18668.1 481 DPDVQVGLGVLFYCAEEYGK 500
                 9***********99888887 PP

>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.2      0.96   8.2e+02       8      30 ..     377     399 ..     375     400 .. 0.83
   2 ?   12.7   0.3    0.0001     0.086       6      31 ..     528     553 ..     528     554 .. 0.95
   3 ?    1.8   0.0      0.28   2.4e+02       4      33 ..     560     589 ..     558     594 .. 0.85

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.96
      TPR_10   8 LanalrqrgrydeAealleeala 30 
                 L+ a  q  + + A++ le+al 
  EEA18668.1 377 LGSAQAQNEKENPALRALEQALK 399
                 88888888899999999999986 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 0.0001
      TPR_10   6 nNLanalrqrgrydeAealleealai 31 
                 n L+++l + gr +eA + +e+al i
  EEA18668.1 528 NRLGATLANSGRSEEAIEAYEKALTI 553
                 78**********************87 PP

  == domain 3  score: 1.8 bits;  conditional E-value: 0.28
      TPR_10   4 slnNLanalrqrgrydeAealleealairr 33 
                 ++ NL++   + g y eA ++l  ala+++
  EEA18668.1 560 ARYNLGVSCINIGCYPEAAQHLLGALAMHK 589
                 567888888888889*************98 PP

>> TPR_3  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       7.2   6.1e+03      15      36 .]     385     404 ..     377     404 .. 0.67
   2 ?    1.7   0.1      0.32   2.7e+02       6      25 ..     487     506 ..     487     511 .. 0.83
   3 ?    7.4   0.0    0.0051       4.4       7      32 ..     530     553 ..     527     556 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 7.2
                 T-HHHHHHH..HHHHHHH-TT- CS
       TPR_3  15 kkyqeArelfsYallaildken 36 
                 +k + A+ ++   ++ +ld++n
  EEA18668.1 385 EKENPALRALE--QALKLDPNN 404
                 55555777766..899999988 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.32
                 HHHHHHHHTT-HHHHHHH.. CS
       TPR_3   6 syAaefynkkkyqeArelfs 25 
                 +++  fy  ++y +A++ fs
  EEA18668.1 487 GLGVLFYCAEEYGKAVDCFS 506
                 578899999*********88 PP

  == domain 3  score: 7.4 bits;  conditional E-value: 0.0051
                 HHHHHHHTT-HHHHHHH..HHHHHHH CS
       TPR_3   7 yAaefynkkkyqeArelfsYallail 32 
                 ++a++ n+++ +eA+e+  Y+ + ++
  EEA18668.1 530 LGATLANSGRSEEAIEA--YEKALTI 553
                 79***************..8766665 PP

>> DUF533  Protein of unknown function (DUF533)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   1.0    0.0031       2.7      15      54 ..     160     209 ..     150     248 .. 0.64
   2 ?    4.7   0.2     0.023        20     122     174 ..     354     407 ..     341     410 .. 0.69

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0031
      DUF533  15 llGskkgrklgkkalklGglAalGglAykayqnwqanqq..........e 54 
                 ++++ + + +g+ + ++Gg+ a+G++  + +   q++q+           
  EEA18668.1 160 MMSGYQRPMMGGYMGAMGGMGAMGMMGPSYMPMQQQQQPgvqeqegkgkG 209
                 45555558999999************988777555555544333333220 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.023
      DUF533 122 dlqelaaav..knpelaaevYlaSllaidedsaaEraYLdeLaqaLgLdpelvae 174
                 +l++la ++  ++  + ++ +++ l   + ++++E+  L++L qaL+Ldp+  ++
  EEA18668.1 354 SLAALAFEAavQKDPQHVQAWTM-LGSAQAQNEKENPALRALEQALKLDPNNLDA 407
                 55555544411444455555554.345688999999999********99987665 PP

>> DUF4192  Domain of unknown function (DUF4192)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   8.8    0.0022       1.9     140     301 ..     208     403 ..     202     414 .. 0.78
   2 ?   -1.3   0.0       2.1   1.8e+03     111     164 ..     561     612 ..     531     652 .. 0.57

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.0022
     DUF4192 140 aGrvvegsReelearlapvegaaaraaqrraaeraaaaleralarprdaerr..sdpaevrraaleavraalarvaagaglsda............... 221
                 +Gr ve + e +ea++a +++a ++a +++a  +++a+l ++ ++ +    +  s+  e  ++ ++ ++a  a +++ ++l+d+               
  EEA18668.1 208 KGRMVELDDENWEAQFAEMDAAGQEAFDDQANHAMEAELNDLDRSVHSTPLQnqSEGFEQFERVWQSAQAENASATTSRQLADDdfeevanlhlgdang 306
                 6999*************99998767777777777777777766655554444445555666666666666666666666666669*9999999999999 PP

     DUF4192 222 .eeaarlavaLtdvrvRDaa.................lalalgeeaaaaerLwlalarrlpgplrAaalaLlAvvawarGdgalAgvaLeaAleadPg 301
                  e    l++  +d+++ D +                 ++ +  e  +  ++ ++  a   ++p   +a ++l+ +  ++ ++  A  aLe Al++dP 
  EEA18668.1 307 wEGFDSLNTRFRDPQLGDYLfeednmfkavgnpfeegMKIMQ-EGGNLSLAALAFEAAVQKDPQHVQAWTMLGSAQAQNEKENPALRALEQALKLDPN 403
                 999999999999999999998888887777777777555555.6666667777778888888999999999999999999999999999999999996 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 2.1
     DUF4192 111 rwwsylcccpeeGtvpdpaasplaaaavlaGrvvegsReelearlapvegaaar 164
                 r+ + + +c + G+ p+ a++ l a a++  +v +  Re++++ ++ v+g +++
  EEA18668.1 561 RYNLGV-SCINIGCYPEAAQHLLGALAMH-KVVEQQGREKAREIVEGVDGIDDA 612
                 555444.6666666666666666666666.233344466666666655554222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (663 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       838  (0.0467399); expected 358.6 (0.02)
Passed bias filter:                      571  (0.0318478); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                        21  (0.00117129); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              21  [number of targets reported over threshold]
# CPU time: 0.75u 0.36s 00:00:01.10 Elapsed: 00:00:00.58
# Mc/sec: 3438.98
//
Query:       EEA18669.1  [L=604]
Description: beta-N-acetylhexosaminidase NagA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.9e-97  326.3   0.4    3.9e-97  325.8   0.4    1.2  1  Glyco_hydro_20   Glycosyl hydrolase family 20, catalytic doma
    4.2e-26   92.2   0.1    8.5e-26   91.2   0.1    1.5  1  Glycohydro_20b2  beta-acetyl hexosaminidase like
    0.00023   21.9   0.1    0.00054   20.7   0.1    1.6  1  Glyco_hydro_20b  Glycosyl hydrolase family 20, domain 2
  ------ inclusion threshold ------
       0.18   11.6   0.9        0.5   10.1   0.4    2.0  2  DUF2247          Uncharacterized protein conserved in bacteri


Domain annotation for each model (and alignments):
>> Glyco_hydro_20  Glycosyl hydrolase family 20, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  325.8   0.4  8.7e-101   3.9e-97       1     353 [.     183     547 ..     183     548 .. 0.92

  Alignments for each domain:
  == domain 1  score: 325.8 bits;  conditional E-value: 8.7e-101
  Glyco_hydro_20   1 fkyRGlmlDvaRhflsveeikrliDamaaaKlNvlHwHltDdqgwrleikkyPeLtekgakreskeseeelsgfYtkedireiveYAaergieVi 95 
                     +++RG+m+D++R+f+++++ik++iD ma++KlN lHwHl D+q+w++++++yP++t+  a+++s+        +Y++e+i++i++YA++r ++V+
      EEA18669.1 183 YSWRGIMIDTGRNFITLPKIKEQIDGMAFSKLNILHWHLDDSQSWPVQMSTYPQMTKD-AYSPSE--------TYSHENIKDIIAYARARAVRVM 268
                     99********************************************************.9***98........9********************* PP

  Glyco_hydro_20  96 pEidmPgHaraalkaypelvtk....ekaeqsveqsvqvevkesvlnptneetyeflekvldevaelfpseyvHiGGDEvkkkqwkkspeiqali 186
                     pE+dmPgH++a++k++++ +      ++++++++ +++ve++ ++l+p n++ty ++ekv+de+++lf ++++H+GGDE++  +++ s+ + + +
      EEA18669.1 269 PEVDMPGHSAAGWKQVDASIVAcansWWSNDNWPYHTAVEPTPGQLDPLNNKTYGVVEKVYDELSSLFTDNFFHVGGDELQIGCYNFSTYVMDYL 363
                     *****************99888899989999**************************************************************** PP

  Glyco_hydro_20 187 keeglksveelqsyfvkrvekilkekgkk.ligWdeilekgk.asklakknttvqsWrelekeaaeklakkgydvilspadalYlDfgqekkeee 279
                     +++  ++++++ +y+v+++ +i+k+ + + l++W++++ ++  a ++ ++  +vqsW++   +++++l++ gydv +s++d++YlD+g++  +++
      EEA18669.1 364 AADPSRTFNDVTQYWVDHAFPIFKNIKDRkLVIWEDLIINDPhAPNVSTDGLLVQSWNN-GLTNIRNLTALGYDVLVSSSDFMYLDCGYGGFVTN 457
                     ***********************9976555******99999878999999*********.789******************************** PP

  Glyco_hydro_20 280 egleiat...........faslekvynyepvakeaas.......tslseeekkkkilGveaalWtEvirdsaeleyrvfPRlaalAErlWsk 353
                     ++++ ++           f+   +  ++++++k++++       + l+e+++ ++++G+ a lW+E++ d+  ++ +++PR+aalAE +Ws+
      EEA18669.1 458 DPRYNVMvnpnavdgtpnFNWGGNGGSWCAPYKTWQRiydydftDGLTETQA-AHVKGAVAPLWSEQV-DDVVISGKMWPRAAALAELVWSG 547
                     ***9999777777777774444444666666666666666555444456666.5**************.*********************96 PP

>> Glycohydro_20b2  beta-acetyl hexosaminidase like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.2   0.1   1.9e-29   8.5e-26       2     137 .]      25     161 ..      24     161 .. 0.91

  Alignments for each domain:
  == domain 1  score: 91.2 bits;  conditional E-value: 1.9e-29
  Glycohydro_20b2   2 wPaPteyti.gsktlrlspsnfrlkvesaaseaveellheafdrtlkelfkskvvpwakeprnskfepkvst..........avskkkediktv 84 
                      +PaP+++t+ +s++++l  +++ ++   +       ++++a++r++ ++ + k+vp a+e+++s+ ep+++           ++ +++++++tv
       EEA18669.1  25 LPAPRSITWgSSGPISLPWDVE-VRLPRN------TIIKDAWNRAWTNINQLKWVPRATEAPISSYEPFPTAspsaavairsQKRHQHSTLRTV 111
                      7********8888999998444.443443......39********************************999********9999999999**** PP

  Glycohydro_20b2  85 evsltsekseaeeltlevdEsYtLsvksasgsakisansvlGalhGLeTlqQL 137
                       vs+t+ +++   l+ +vdEsYtL++ s+s++  i+an+ +G+lh+++TlqQ+
       EEA18669.1 112 TVSVTNLEAD---LQADVDESYTLVLDSESSTLAITANTTWGCLHAFTTLQQI 161
                      *******986...*************99999*********************6 PP

>> Glyco_hydro_20b  Glycosyl hydrolase family 20, domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.7   0.1   1.2e-07   0.00054      70     123 ..     103     179 ..      25     180 .. 0.58

  Alignments for each domain:
  == domain 1  score: 20.7 bits;  conditional E-value: 1.2e-07
  Glyco_hydro_20b  70 d...................aelgaEgYrLavded..titiegkdtdGlfyGvqTLrqllpqaagg.tl.paveirD 123
                      +                   +   +E+Y+L  d +  t +i++++t G +++ +TL+q++  ++++  + + v+i+D
       EEA18669.1 103 HqhstlrtvtvsvtnleadlQADVDESYTLVLDSEssTLAITANTTWGCLHAFTTLQQIVIYQNNQlIIeQPVHIED 179
                      1334444444445555555588899***998888666**********************966654432213556666 PP

>> DUF2247  Uncharacterized protein conserved in bacteria (DUF2247)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0      0.57   2.6e+03       9      31 ..     182     204 ..     178     216 .. 0.84
   2 ?   10.1   0.4   0.00011       0.5     114     148 ..     226     258 ..     196     262 .. 0.76

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.57
     DUF2247   9 kldWkdiyvGleknlisadevie 31 
                  ++W+ i +   +n+i+  ++ e
  EEA18669.1 182 LYSWRGIMIDTGRNFITLPKIKE 204
                 589*************9988865 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00011
     DUF2247 114 dyPeeienfirYmppkdgyspseyseeeninrlie 148
                  +P +++     +  kd+yspse +++eni+++i 
  EEA18669.1 226 SWPVQMSTY--PQMTKDAYSPSETYSHENIKDIIA 258
                 355556555..67789****************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (604 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      406  (0.0226449); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.45
# Mc/sec: 3996.85
//
Query:       EEA18670.1  [L=413]
Description: hypothetical protein PMAA_009530 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
       0.15   12.3   0.6       0.31   11.3   0.6    1.5  1  Chordopox_A13L  Chordopoxvirus A13L protein
        1.2    7.4   5.0        1.8    6.8   5.0    1.2  1  DUF2070         Predicted membrane protein (DUF2070)


Domain annotation for each model (and alignments):
>> Chordopox_A13L  Chordopoxvirus A13L protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.6   3.4e-05      0.31       1      27 [.     346     372 ..     346     383 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 3.4e-05
  Chordopox_A13L   1 MiadlllliiCvaivglivYgiYnrkk 27 
                     M +++l l++C  +v+++++ +Y+ ++
      EEA18670.1 346 MCTEILSLVVCYCVVVFVLWVVYKIRH 372
                     899********************8443 PP

>> DUF2070  Predicted membrane protein (DUF2070)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   5.0    0.0002       1.8      64     133 ..     311     378 ..     300     380 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0002
     DUF2070  64 grltykrslflalltelivviisllaillsallqalvllalvlslalvfalrllvlvavsdesllkavlp 133
                 +r ++ rs++l ll+ +++v++sl  i++  l   +++   +lsl++   ++++vl++v + ++++++++
  EEA18670.1 311 SRTYWIRSMLLGLLAPTLMVAFSLEMIAIDSLS--VLMCTEILSLVVCYCVVVFVLWVVYKIRHRNSSFM 378
                 4468999*******************9999744..677777899******************99998865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (413 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       801  (0.0446762); expected 358.6 (0.02)
Passed bias filter:                      551  (0.0307323); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.25s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 2809.73
//
Query:       EEA18671.1  [L=677]
Description: copper amine oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   5.7e-156  519.5   0.0     7e-156  519.2   0.0    1.1  1  Cu_amine_oxid    Copper amine oxidase, enzyme domain
    5.6e-07   29.9   0.0    5.5e-06   26.7   0.0    2.3  2  Cu_amine_oxidN3  Copper amine oxidase, N3 domain
    2.3e-06   27.7   0.1    5.6e-06   26.5   0.1    1.7  1  Cu_amine_oxidN2  Copper amine oxidase, N2 domain
  ------ inclusion threshold ------
       0.18   11.8   0.1       0.32   11.1   0.1    1.4  1  FSAP_sig_propep  Frog skin active peptide family signal and p


Domain annotation for each model (and alignments):
>> Cu_amine_oxid  Copper amine oxidase, enzyme domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  519.2   0.0  1.6e-159    7e-156       2     410 .]     233     646 ..     232     646 .. 0.96

  Alignments for each domain:
  == domain 1  score: 519.2 bits;  conditional E-value: 1.6e-159
                    ----TT---SEEETTTEEEETTEEEEEEEETTTEEEEEEEEETTEEEEEEEEEEEEEEEE--SSHHHHH-EEEGGGT.-SGGG-----TTTSS-TT CS
  Cu_amine_oxid   2 evvqpeGpsfkvdegnlvewqkWsfrvgfnrreGlvlhdvrykgrrilyrlslsemvvpYgdprppasrkaafDlgeyglGklansLelgcDClge 97 
                    +v qp+G+sf+v +g+lv+wqkW+fr+gfn+reG+vlhdv+y+gr++++rlslsem+vpYgdpr+p+srk++fD+g++g+G +an+L+lgcDClg 
     EEA18671.1 233 TVHQPQGASFHV-DGHLVTWQKWRFRLGFNWREGMVLHDVTYDGRELFHRLSLSEMFVPYGDPRTPYSRKSVFDVGDIGAGVAANNLALGCDCLGL 327
                    689*********.7********************************************************************************** PP

                    -EEEEEEEEE..TEEEEEEEEEEEEEEE-S-SEEEE-S....EEEE--EEEEEEEEEEETTEEEEEEEEE-TTS-EEEEEEEEE----EE-T.... CS
  Cu_amine_oxid  98 ityldavladssgepvtiknaiCifEedagilwkHtdfrtgraevtrnreLvvrtiatvgNYdYifdyiFkqdGsievevratGilstaalaeeee 193
                    i+y++ +++ds+g+pv  +na+C++E d+gi wkHtd+ t++++++r+r Lv++ti+tvgNY+Yif+++F+q+++++++++atGilst +++++ +
     EEA18671.1 328 IKYFSFTISDSNGNPVPKPNAVCMHEIDDGIGWKHTDSATKQVSIVRSRVLVLQTIITVGNYEYIFMWHFDQAAALHYRIQATGILSTVPITPGVT 423
                    ********************************************************************************************9999 PP

                    .GG--EEETTEE---EEEEEEEEEEE-T.SSEEEEEEEEE-T..TT.T-...-EEEEEEEEEE--BGGG-EE--.-GG-EEEEEEEEEEE-.TTS- CS
  Cu_amine_oxid 194 skygtrvapgvlasiHqHlfslrvDldidgeknsvveeelvpeepelgeenpagnafkvektvletekeaaldldpeknrvlkivnenkkn.klge 288
                     ++gt+v++gv+a++HqH+f+lr+D+++dg++ns+vee++ ++ p  ++ npag+++ ++++v++t+  ++ ++    nrv+ki+n++  n ++g+
     EEA18671.1 424 VPWGTNVNEGVMAPYHQHVFALRIDPALDGDRNSFVEEDSIAM-P-FDAYNPAGVGYITKQKVFTTS--GYSEA--LPNRVHKIINPSIINkVSGK 513
                    9*****************************99********885.4.45679****************..66655..349************9**** PP

                    EEEEEEE-S----..---SS-TTTTTTTGGGG-SEEEEE--TT---S--TTGG-TTS.............-.--GGGG-.S--B-SSEEEEEEEEE CS
  Cu_amine_oxid 289 pvgYklvpssaasqlllakesslvakraefakhhlwvtkykdselyaageynnqskg............ep.vglakwvednesieneDlVvWvtl 371
                    pv+Y++++  a++q+lla+++s++ +rae+a + +wvt ykd+elyaag+y++qs              ++  ++a+w+++n++++neD+VvW+++
     EEA18671.1 514 PVAYTVHS--AQKQMLLAHPQSWHGRRAEYALQPYWVTSYKDGELYAAGDYTYQSLPtdvllhggssppQRgGDVATWAARNDKVDNEDIVVWHSI 607
                    ********..55899*************************************999887788877776553479*********************** PP

                    EEEE---GGGSS-TTTSEEEEEEEEES-SSS-GGGG-S- CS
  Cu_amine_oxid 372 GltHvpraeDfPvmpvetvsflLkPvnFfdenpaldvpp 410
                    +ltH+pr+eD+Pvmp+et++++LkP++Ff+ npaldvp+
     EEA18671.1 608 SLTHNPRPEDYPVMPCETMTVSLKPSGFFEYNPALDVPQ 646
                    *************************************96 PP

>> Cu_amine_oxidN3  Copper amine oxidase, N3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.0   0.0      0.26   1.2e+03       2      63 ..       6      70 ..       5      84 .. 0.72
   2 !   26.7   0.0   1.2e-09   5.5e-06       6      93 ..     105     193 ..     102     196 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.0 bits;  conditional E-value: 0.26
                     ---HHHHHHHHHHHH.TGGGGHHHHHHHHTTT.T---EEEE--SS-SSST....T--EEEEEEEE- CS
  Cu_amine_oxidN3  2 pvlleelaeieevik.elpqfkealkkrgienldkvvltpltvgyrgeks...egkRllkalvyyr 63
                     p++ +e ++++++i+  +p++++  k+ ++++++k+ l    ++ r+++       R++  l yy+
       EEA18671.1  6 PLTPAEITATAKLIQsVNPKHSAHFKNISLFEPAKRELRKYLAAERNNAPpvrALTRRASSL-YYH 70
                     67889999999999988999999999999999999999888888888877433233333333.443 PP

  == domain 2  score: 26.7 bits;  conditional E-value: 1.2e-09
                      HHHHHHHHHHHTGGGGHHHHHHHHTTT.T---EEEE--SS-SSST.T--EEEEEEEE--SSS...-GCGSEEE.EEEEEE--SSSGGG-EE CS
  Cu_amine_oxidN3   6 eelaeieevikelpqfkealkkrgienldkvvltpltvgyrgeksegkRllkalvyyrtesa...nlyahPiegLellvDleakkvieitd 93 
                      +e  e+ +   ++p++ e +k+ gi +  +vv++++  g +     ++R+++  +y + +s    n y  P+  + +++D  +k+v++i d
       EEA18671.1 105 DEALEVRRKCLSNPKVVERIKQYGILDELEVVCDTWPYGRDTDDF-TRRMTQCYLYAKYKSHpgsNAYDNPLP-FSPIIDYVTKEVVDIID 193
                      5666777777899***********99999**********776666.**********988877789********.*************9976 PP

>> Cu_amine_oxidN2  Copper amine oxidase, N2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.5   0.1   1.2e-09   5.6e-06       1      57 [.       2      58 ..       2      92 .. 0.78

  Alignments for each domain:
  == domain 1  score: 26.5 bits;  conditional E-value: 1.2e-09
                     HHHHHHHHHHHHHCCCCCCCCTCT-TTSEEEEEEEEE---HHHHHHH..HHCH---S-E CS
  Cu_amine_oxidN2  1 hpLdaltaaeinkvesilkssaletskknsffeveLeePdKkavlqf..lekgeppppR 57
                     hpLd+lt+aei ++   ++s +   ++   f  ++L eP+K   +++   e+++ pp R
       EEA18671.1  2 HPLDPLTPAEITATAKLIQSVN--PKHSAHFKNISLFEPAKRELRKYlaAERNNAPPVR 58
                     9******************999..677899*****************544566666665 PP

>> FSAP_sig_propep  Frog skin active peptide family signal and propeptide
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.1   7.2e-05      0.32      11      45 ..      76     111 ..      76     112 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 7.2e-05
  FSAP_sig_propep  11 LFLGlVSlSlCEEekredeeeneeeeekeeqs.eek 45 
                      LFLG+V+l   E ek e+ ee+   +++ ++  e++
       EEA18671.1  76 LFLGVVNLTASEVEKIEKLEEGYHGQADTDEAlEVR 111
                      8******************99888776444333555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (677 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       392  (0.021864); expected 358.6 (0.02)
Passed bias filter:                      360  (0.0200792); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.65u 0.30s 00:00:00.95 Elapsed: 00:00:00.49
# Mc/sec: 4142.15
//
Query:       EEA18672.1  [L=769]
Description: pheromone-regulated membrane protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-68  230.3  12.6      4e-64  216.3   3.3    2.2  2  ThrE      Putative threonine/serine exporter
    1.4e-11   44.6   5.5    1.4e-11   44.6   5.5    3.3  3  ThrE_2    Threonine/Serine exporter, ThrE


Domain annotation for each model (and alignments):
>> ThrE  Putative threonine/serine exporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  216.3   3.3   4.5e-68     4e-64       2     240 ..     329     578 ..     328     579 .. 0.94
   2 !   19.3   1.9   6.6e-08    0.0006     114     198 ..     608     692 ..     599     700 .. 0.90

  Alignments for each domain:
  == domain 1  score: 216.3 bits;  conditional E-value: 4.5e-68
        ThrE   2 lilrlGeiLlesGaetyrvedtmkriaralgleevevfvtptsiivsvdeeeesittvrrv.rsrgvnleklsevnelsreiaageisleeaeerLdeI 99 
                 +++ l+++++++Ga+++r+e++m+ +a++l+l +++++++p ++i+s+d+ ++ +t+vr v   +gv+l +l++++++++++++++i+++ea+++Ld++
  EEA18672.1 329 YLITLCRAMMRFGAPSHRLEEYMSLTAKVLDL-HAQFLYLPGTMIMSFDDVSTRTTEVRLVrVAQGVDLARLEDTQNIYKNLVHDKITVDEATSELDAV 426
                 6789****************************.9**************766677777****99************************************ PP

        ThrE 100 erskpryprwlvvlaaglaaaafallf.ggdwidflvaflagllggllrlll.akrglnsfvleavaaflasllallavsl......glgln......p 184
                  +++ +yp+wlvvl++g+a++++++++ ++++id++++f++g+l+gll+l++ ++++l+s+v+e++a +l+s+la++++s+      g   +      +
  EEA18672.1 427 INRSAKYPTWLVVLCYGFASVSVGPFAfEARPIDMPITFFLGCLLGLLQLVFsPRSSLYSNVFEVIACILTSFLARAFGSIrngvvdG---TqqyffcF 522
                 *************************998************************99**************************87655542...13456667 PP

        ThrE 185 daiiigsillLvPGlpltnavrDllsgdlvsGlaRlveailialaiafGivlalsl 240
                 +a++++si+l++PG+ +++++++l+s++++ G++R+v+ai+++l++++Gi++++++
  EEA18672.1 523 SAMAQSSIALILPGFLVLSSSLELQSHQIIPGSIRMVYAIIYSLFLGYGITVGTTI 578
                 *****************************************************998 PP

  == domain 2  score: 19.3 bits;  conditional E-value: 6.6e-08
        ThrE 114 aaglaaaafallfggdwidflvaflagllggllrlll.akrglnsfvleavaaflasllallavslglglnpdaiiigsillLvPG 198
                 +++l+  +++++ +g++++++v+ l++  g++++++   k + n+ ++++++af +++l+ l  +l ++ +++++i+ +i +LvP 
  EEA18672.1 608 FVALFVIFLVIINQGKLKQVPVMILIAEAGYIANYFSnLKLQSNPELANTLGAFAVGVLGNLYSRL-WHGHAATAILPAIFVLVPS 692
                 5677777888888************************89*********************999997.78999*************5 PP

>> ThrE_2  Threonine/Serine exporter, ThrE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.5     0.016   1.4e+02      47     100 ..     438     494 ..     426     510 .. 0.75
   2 ?    0.9   1.5     0.051   4.6e+02      79     128 ..     528     577 ..     520     579 .. 0.84
   3 !   44.6   5.5   1.6e-15   1.4e-11       4     128 ..     608     754 ..     605     755 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.016
      ThrE_2  47 ialasflaalaigllsellArriktPvtvfl..ipgllplv..PGlaaYktvlslvqg 100
                 ++l++ +a++++g ++ + Ar i +P+t fl    gll lv  P  ++Y+ v++++  
  EEA18672.1 438 VVLCYGFASVSVGPFA-FEARPIDMPITFFLgcLLGLLQLVfsPRSSLYSNVFEVIAC 494
                 6788889999999976.57999999999998334578877766777777777777665 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.051
      ThrE_2  79 pgllplvPGlaaYktvlslvqgnleeavengiealliagalavGlvlvsl 128
                 +++  + PG  + ++ l+l ++++      ++ a++  + l  G+++ ++
  EEA18672.1 528 SSIALILPGFLVLSSSLELQSHQIIPGSIRMVYAIIYSLFLGYGITVGTT 577
                 5778889****************999999999999999999888888765 PP

  == domain 3  score: 44.6 bits;  conditional E-value: 1.6e-15
      ThrE_2   4 lafiaalgfavifnvpkrallvagllGavgwlvylllme.lgvsialasflaalaigllsellArriktPvtvflipgllplvP...........Glaa 90 
                 +++++ + + +i++ + ++++v+ l++ +g++ +++    l+++ +la+ l+a+a+g+l++l++r+ +  + + + p+++ lvP           G++ 
  EEA18672.1 608 FVALFVIFLVIINQGKLKQVPVMILIAEAGYIANYFSNLkLQSNPELANTLGAFAVGVLGNLYSRLWHGHAATAILPAIFVLVPsglaaqgslvsGVQS 706
                 56777788888999999****************9998877********************************************744444444444444 PP

      ThrE_2  91 Yktvlslvqgn..........leeavengiealliagalavGlvlvsl 128
                  + +++ ++g+           +  ++ g+ ++++a+++ vGl+l+ +
  EEA18672.1 707 ASEIRANITGDhsnypppsspESSTYSMGYGMIQVAIGITVGLFLAAV 754
                 4444444444478889999888899999****************9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (769 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       606  (0.0338); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.68u 0.29s 00:00:00.97 Elapsed: 00:00:00.47
# Mc/sec: 4923.03
//
Query:       EEA18673.1  [L=393]
Description: D-aminopeptidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.5e-112  376.0   1.1   1.9e-112  375.7   1.1    1.0  1  Peptidase_S58  Peptidase family S58


Domain annotation for each model (and alignments):
>> Peptidase_S58  Peptidase family S58
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  375.7   1.1  1.1e-116  1.9e-112       1     296 [.      26     375 ..      26     377 .. 0.96

  Alignments for each domain:
  == domain 1  score: 375.7 bits;  conditional E-value: 1.1e-116
  Peptidase_S58   1 naitDVaGvrVghatlae.......ge.vrtGvTvilprgnlfkekvvAavdvlnGfgkttgtdqleelglletpivLtntlsvgaaadgvvewll 88 
                    n++tDV+Gv V+++++++       g+ ++tGvTvilpr+++f+++++A+++++nG+g++tg+++l+e+gll++pivLtn++svg +++gv+++++
     EEA18673.1  26 NSLTDVPGVLVHTESIIKkpseterGHaINTGVTVILPRREWFNNACYAGYFRFNGSGEMTGAHWLDETGLLNSPIVLTNSFSVGPCYSGVYQYAI 121
                    99**************889999**9555******************************************************************** PP

  Peptidase_S58  89 e...eeeeeearsvvpvVaetnDgvlndiragavkeehvaealaaAaaapvaeGnvGaGtGmiafglKGGiGtaSrvlee....gekeytvgalvq 177
                    +   ++ + ++++++pvVaet+D +l+di a+av++e v++ +++A++a+v+eGn+G+GtGm++ g+K+G+G aSr +e     ++k+ytv+alvq
     EEA18673.1 122 ReyaKNGTPADWFILPVVAETCDLFLSDIAAMAVTPEMVVRGIDNASSARVPEGNTGGGTGMTCQGFKAGTGCASRLIEGiefgEKKTYTVAALVQ 217
                    *7654444899*******************************************************************9777866677******** PP

  Peptidase_S58 178 aNfggredlriagvpvgkelaeea.........................kdgsiivvvatDapLskrqlkrlakraalGlartgsphsngsGDivl 248
                    aNfg ++d+r+ gvpvg+++ e++                         kdgsiivv+atDapL++ ql+rlakra++G+ar+g+++sn+sGD+++
     EEA18673.1 218 ANFGAKRDMRVGGVPVGRIMLEREeaqkenpapnagtsttadeekrlasKDGSIIVVIATDAPLHPVQLQRLAKRATVGVARVGGWGSNSSGDLFI 313
                    ******************99988889********************************************************************** PP

  Peptidase_S58 249 afstaekepe..............evledeeldelfeaaaeaveeAilnallaAetvtgrdg 296
                    afstae++p+              +v++d ++++lfeaaa+++eeAi+nal+aA+t++g  g
     EEA18673.1 314 AFSTAENIPReptfswnptveqtvSVVQDVTINSLFEAAADSTEEAIYNALVAAQTMEGPMG 375
                    ********99**************99********************************9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (393 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       419  (0.02337); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 2580.13
//
Query:       EEA18674.1  [L=1446]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.3e-38  131.7   0.2    5.9e-38  130.9   0.2    1.4  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    1.8e-07   30.9   0.7    4.8e-07   29.5   0.0    2.0  2  gag_pre-integrs  GAG-pre-integrase domain
    0.00055   20.1   0.0     0.0013   18.9   0.0    1.7  1  rve              Integrase core domain
  ------ inclusion threshold ------
      0.026   14.1   0.0       0.05   13.1   0.0    1.4  1  RVT_1            Reverse transcriptase (RNA-dependent DNA pol
      0.076   12.9   0.0       0.18   11.7   0.0    1.6  1  Flg_hook         Flagellar hook-length control protein FliK
       0.12   12.6   3.2       0.31   11.3   3.2    1.7  1  Orthopox_F14     Orthopoxvirus F14 protein
        9.5    6.3  13.2         20    5.2   5.3    2.7  2  Transformer      Fruit fly transformer protein


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  130.9   0.2   2.3e-41   5.9e-38       9     234 ..     950    1172 ..     941    1178 .. 0.91

  Alignments for each domain:
  == domain 1  score: 130.9 bits;  conditional E-value: 2.3e-41
       RVT_2    9 PkdrkaigsrWvftkkkddl.kevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeeelvvhqldvdsafLnaeldeevyvkqPpGfe 104 
                   k+++ +   W++  k+d++ + vk karlv++G  q    d  +++a  +   s r ++a+aa  +l + q d   af+na+ldee++++  pG+ 
  EEA18674.1  950 AKGKQILDCMWIYVYKQDKKgRLVKCKARLVVRG-DQEKRDDMRDTYAATLAARSFRTFMAIAARFDLELKQYDAVNAFVNAKLDEEIFMRMAPGYR 1045
                  577888999********999899***********.577889******************************************************96 PP

       RVT_2  105 idreeekvykLnkslyGlkqapllWnekidkvLkklgferseaesGlyvrgtgegklivalyvddlliagsdikil..edvkkelakkfklkdlgkv 199 
                     e++k+y+Lnk+lyGl+++pllW+++++++L klgf+  + e    +++     +++  yvdd+++a ++++ l  + + ++l +k++++   ++
  EEA18674.1 1046 ---ESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFRAVPHEPCCMLKS----GVMLFFYVDDIVVAYKKSRQLeaNSILNQLRAKYNISGGEDL 1135
                  ...46****************************************999999....78999*********9999877225799*************** PP

       RVT_2  200 skfLGieiaq..eaggiklsladyiakvvkkfeltda 234 
                  + fLG+ i++  ++  i ls+a yi k++k ++ ++a
  EEA18674.1 1136 EWFLGMRIIRdrSNKMIWLSQATYIDKIAKLADTQQA 1172
                  ********986568889***********998876655 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.1       2.2   5.6e+03      56      63 ..      52      59 ..      39      59 .. 0.77
   2 !   29.5   0.0   1.9e-10   4.8e-07      19      66 ..     301     352 ..     284     353 .. 0.76

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 2.2
  gag_pre-integrs 56 sevCeaCq 63
                      +vCeaC+
       EEA18674.1 52 RPVCEACE 59
                     579****6 PP

  == domain 2  score: 29.5 bits;  conditional E-value: 1.9e-10
  gag_pre-integrs  19 knkssinlWHrRLGHpsfsrlkkLfkkgl...lpglkisk.sevCeaCqlgK 66 
                        k ++n+WH RLGHp+ + lk+L+       l g++++    +Ce+C  +K
       EEA18674.1 301 ERKADANRWHARLGHPGPEVLKHLAGAAKgvrLTGISKGPtTVECESCGTSK 352
                      35899********************8544334555554433559****9988 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.0   5.1e-07    0.0013       2     116 ..     366     482 ..     365     484 .. 0.86

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 5.1e-07
         rve   2 trpgelwqvDvtvvripdgggkayllvvvddfsrlilaealsdemdastvlalleravarfggve...pervlsDngseytskafrefla.dlgirvsf 96 
                 ++pge++ +D+  ++ ++  g++ l  ++d fs++++ ++++++   + +l++l+ +++++ +     p ++ +Dn  + +  +++ +l+ + +i +++
  EEA18674.1 366 HAPGEHLAIDFHDFAESTMHGEKTLMLITDRFSGFMWDYYMTSH-RGDEILETLKWFLDYLEKAYmisPVKIEMDNEIAKRP-EVKHYLEhEKRIILQP 462
                 89**********777799999***********************.**********99999999879**********976664.5555555157899999 PP

         rve  97 trpgrpqdnGkvErfhrtlk 116
                 ++++    nG +Er   ++k
  EEA18674.1 463 SPAHTQALNGGAERSGAIIK 482
                 99999999999999876666 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0     2e-05      0.05     117     185 ..    1039    1121 ..    1010    1131 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2e-05
                  .........TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T................TEEECTTEEEEEESSHHH..HHHHHH CS
       RVT_1  117 rv.nge.eskgryekkglpqGsvlSPllfnlfmnellrelrkra..........kgvtllrYaDDililskskee..lqelle 185 
                  r+  g  es+++y+ +    G+  SPll++  +++ l +l  ra          +gv l  Y+DDi++++k+  +  ++++l+
  EEA18674.1 1039 RMaPGYrESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFRAvphepccmlkSGVMLFFYVDDIVVAYKKSRQleANSILN 1121
                  44344447899999999999***************9999999999***************************88844444454 PP

>> Flg_hook  Flagellar hook-length control protein FliK
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0     7e-05      0.18      34      69 ..    1332    1367 ..    1324    1383 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 7e-05
                  ETTEEEEEEEE-SCHHHHHHHHTHHHHHHHHHCCTT CS
    Flg_hook   34 rggqlsvqltaenpetrelLeqnlprLreaLaaaGl 69  
                  r +  ++++  +n++t+ lLe+++prLr+ L+   +
  EEA18674.1 1332 RFQTPTLHVYCDNQQTLGLLEKDAPRLRTKLRHVDI 1367
                  55566899**********************987544 PP

>> Orthopox_F14  Orthopoxvirus F14 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   3.2   0.00012      0.31      32      70 ..     629     666 ..     618     669 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00012
  Orthopox_F14  32 idedditellniltelGcdvdfdedfsdiaddvleslie 70 
                   +  ++it ll  l +lG d dfd++++d+ d + + +++
    EEA18674.1 629 VSTQEITRLLTKL-DLGTDADFDDEYADLIDHITDVVFD 666
                   5667888888776.79***************99887765 PP

>> Transformer  Fruit fly transformer protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   5.3    0.0079        20      66     111 ..       5      51 ..       2      58 .. 0.78
   2 ?    4.9   1.0    0.0095        24      54      74 ..     113     133 ..      86     142 .. 0.76

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.0079
  Transformer  66 saeresrqrrrrsrsrsrrrsdsrsksssst.errrrsrsrsrysrt 111
                  s e +    r+ srs +r+r ++rs+s+s    r+++++ +++y+ t
   EEA18674.1   5 SDEESYHYGRQPSRSLERKRGRTRSRSRSIGpPRKKKNQGPEQYQTT 51 
                  445555667899***************99875788888888887665 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.0095
  Transformer  54 rerrtrsrsrsqsaeresrqr 74 
                   + ++rsrsrs+s er+ ++ 
   EEA18674.1 113 SNAQVRSRSRSKSRERQECKA 133
                  455889999999999999975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1446 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       527  (0.0293937); expected 358.6 (0.02)
Passed bias filter:                      456  (0.0254337); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 1.06u 0.37s 00:00:01.43 Elapsed: 00:00:00.61
# Mc/sec: 7183.75
//
Query:       EEA18675.1  [L=277]
Description: hypothetical protein PMAA_009580 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.078   13.4   4.0          5    7.6   0.5    2.4  2  REV1_C    DNA repair protein REV1 C-terminal domain
       0.26   11.7   1.4        3.4    8.1   0.3    2.6  2  IL32      Interleukin 32


Domain annotation for each model (and alignments):
>> REV1_C  DNA repair protein REV1 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   0.2     0.001       9.3      43      82 ..     147     186 ..     115     188 .. 0.86
   2 ?    7.6   0.5   0.00055         5      16      74 ..     206     261 ..     198     270 .. 0.90

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.001
      REV1_C  43 avavlkwlrvlleeeeeskeeeageaWekafrevkeavqe 82 
                 ++++  w+++ +  + +++   ++ +W++a+ ++ke+v++
  EEA18675.1 147 IEQIFIWMKQTVSPSYHKTCIAVTANWKEAYINLKEQVNQ 186
                 45677799999988889999999***************96 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.00055
      REV1_C  16 egPneeDvealakyLkkvv..eeerdlekavavlkwlrvlleeeeeskeeeageaWekafr 74 
                  +P  +D+ea  +  ++++  +e + +  a +vl w  + l+       +  ++aW +a++
  EEA18675.1 206 LKPSTRDLEAWITKWEELLleAERKSMVIADDVLDWSTRFLDAI-----RPLDDAWTTAYE 261
                 57999*****99999999988888*******************9.....99*******997 PP

>> IL32  Interleukin 32
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.3   0.00038       3.4      54      84 ..     145     175 ..      80     179 .. 0.80
   2 ?    1.8   0.0     0.034   3.1e+02      40      66 ..     194     220 ..     177     233 .. 0.76

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00038
        IL32  54 qklrdvlaWlkekaaacleAlvsavkavwkv 84 
                 + ++++++W+k+++  + +  + av a wk+
  EEA18675.1 145 KAIEQIFIWMKQTVSPSYHKTCIAVTANWKE 175
                 446789***********************96 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.034
        IL32  40 kvlrrfqallrsLqqklrdvlaWlkek 66 
                 ++   + + lrsL+ + rd+ aW+ + 
  EEA18675.1 194 RIKDEYDQHLRSLKPSTRDLEAWITKW 220
                 3344688999*************9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (277 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       659  (0.0367561); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.34s 00:00:00.99 Elapsed: 00:00:00.57
# Mc/sec: 1456.05
//
Query:       EEA18676.1  [L=212]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.6e-17   63.7   0.0    2.9e-17   62.9   0.0    1.3  1  Pkinase      Protein kinase domain
    4.5e-07   29.4   0.1    3.5e-06   26.5   0.0    1.9  2  Pkinase_Tyr  Protein tyrosine kinase


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.9   0.0   3.2e-21   2.9e-17     121     264 .]      28     209 ..      14     209 .. 0.84

  Alignments for each domain:
  == domain 1  score: 62.9 bits;  conditional E-value: 3.2e-21
                 -SS-SGGGEEEE.TTTE......EEE-SGTTSEESSSSCS.BCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHHHHHSS..-STTTSSHHHHHHHH CS
     Pkinase 121 HrDlKpeNiLid.ekge......lKitDFGlakelesssk.ltsfvgtseYlAPEvlkeneyskkvDvWslGvilyelltgk..ppfsgekgkekveke 209
                   D+K +N+L++           ++++DFG   +++ss     + +gt+ +++PE   + + s+++D+Ws G +l++ll+g+  ++f+ +   +++e +
  EEA18676.1  28 DIDIKLSNVLVNyGC-TnirftdVQLADFGSTVNINSSFAqNGDSIGTPIFRSPEAQLQMKWSTETDIWSFGAMLISLLYGHgfHIFKPDVPVDHHEYD 125
                 57**********433.2467888************9987768899***********999999*****************98744678866666666666 PP

                 HHTHHHHHHHCTSHH...HHHTTS.............................-HHHHHHHHHHT-SSGCCSTTHHHHHTSGGG CS
     Pkinase 210 ldqlekilkilgetkeklpeasei.............................seeakdllkkllkkdpkkRltaeellqhpyl 264
                 ++ l+k  + +g+  e++++  +                               +e k+++ +++k dp++R++a++ll+++++
  EEA18676.1 126 VKILMKQHRCFGPFPESFEQIADQerlavliwvmqnsppetlkpfhltstkeiCQEDKEFVLRIMKLDPRDRPSARQLLKDDWF 209
                 666777777777544444444444667999********************9999999**************************8 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.5   0.0   3.9e-10   3.5e-06     128     199 ..      30     105 ..      14     131 .. 0.87
   2 ?    0.9   0.0     0.025   2.2e+02     226     257 ..     174     205 ..     164     206 .. 0.83

  Alignments for each domain:
  == domain 1  score: 26.5 bits;  conditional E-value: 3.9e-10
                  T-SGGGEEEEE......TTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSEEEHHHHHHHHHHHHHHHH CS
  Pkinase_Tyr 128 dlaarNvLlse......nkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekkftsksDvWsfGvllwEif 199
                  d+   NvL++        + v+++DfG + +i  +++  +++++     + +pE+  ++k ++++D+WsfG +l+ ++
   EEA18676.1  30 DIKLSNVLVNYgctnirFTDVQLADFGSTVNI--NSSFAQNGDSIGTPIFRSPEAQLQMKWSTETDIWSFGAMLISLL 105
                  778889999976666656789******99999..6777777777777789**********************998776 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.025
                  BBTTSBHHHHHHHHHHT-SSGGGS--HHHHHH CS
  Pkinase_Tyr 226 kpekcpeelyelmkkcweedpeeRptfselve 257
                    +++++e +e++ + ++ dp++Rp+ ++l++
   EEA18676.1 174 STKEICQEDKEFVLRIMKLDPRDRPSARQLLK 205
                  556677788999999***********999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (212 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       447  (0.0249317); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.36s 00:00:00.96 Elapsed: 00:00:00.56
# Mc/sec: 1146.77
//
Query:       EEA18677.1  [L=135]
Description: hypothetical protein PMAA_009600 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (135 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       293  (0.0163422); expected 358.6 (0.02)
Passed bias filter:                      271  (0.0151152); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.54u 0.36s 00:00:00.90 Elapsed: 00:00:00.54
# Mc/sec: 746.01
//
Query:       EEA18678.1  [L=94]
Description: hypothetical protein PMAA_009610 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (94 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       447  (0.0249317); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.52u 0.35s 00:00:00.87 Elapsed: 00:00:00.54
# Mc/sec: 520.95
//
Query:       EEA18679.1  [L=247]
Description: hypothetical protein PMAA_009620 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-22   80.1   0.1    1.4e-13   50.4   0.0    2.0  2  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.4   0.0   7.8e-18   1.4e-13     142     291 ..       2     151 ..       1     152 [. 0.85
   2 !   29.3   0.0     2e-11   3.6e-07     381     460 ..     151     237 ..     146     240 .. 0.84

  Alignments for each domain:
  == domain 1  score: 50.4 bits;  conditional E-value: 7.8e-18
                 HHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHH...HHHCHHHHCCCCCHHHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHCSCS CS
        p450 142 tellskaaldvigsilFgarfdlledeklselvkaveelss...llskssvqllllfpllkylptkllrklkeavkklkdlldklieerretldsakks 237
                 + + s+ +ld+ig +++g+ f++l +++++ ++++ e l+     l + sv+++l+ ++++ +  +l+r +++ + +l  +   ++ e+re l+s+ k 
  EEA18679.1   2 SVWASRLTLDIIGPVAMGCDFQSLLNKENKIADNFLEILNPsreKLIFLSVNVILPQWIAHRIHLRLNRVIDQETGFLRAVCHDIVLEKREALKSH-KV 99 
                 6799**********************998666666655554666677889999999999999999*******************************.56 PP

                 SCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        p450 238 rrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLak 291
                 + + l a +  + + +g  ++sd+el+ ++l++l+aG++Tt+ +l+wa y+L +
  EEA18679.1 100 DTKALEADIFGTIMLRG--EFSDDELVDQMLTFLAAGHETTARALTWACYLLCE 151
                 77777777777544555..5******************************9975 PP

  == domain 2  score: 29.3 bits;  conditional E-value: 2e-11
                 TS--GGGGB-TTS.........CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGEEESSCSSEEESSSSE CS
        p450 381 eeFdpeRFldekg.........nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdpppileksglllppkpik 460
                 e+F peR+ d++               +fa + F  G R CiG++lAr el+ + a ++ +F +++q+ +++  i    +++++pk+++
  EEA18679.1 151 EQFIPERWIDADDkghsivnhhGGAPTNFAQITFLHGQRLCIGKGLARAELRCVAAGVVGRFVMQMQRPEEEIHIAG--AVTTKPKEGM 237
                 89******9998889**99987334578999**********************************966555555544..4888888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (247 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       421  (0.0234815); expected 358.6 (0.02)
Passed bias filter:                      402  (0.0224218); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.30s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 1617.57
//
Query:       EEA18680.1  [L=580]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.8e-46  157.8  49.3    9.4e-44  149.9  41.4    2.0  2  AA_permease_2  Amino acid permease
    1.9e-22   79.5  32.1    1.9e-22   79.5  32.1    1.6  2  AA_permease    Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  149.9  41.4   1.1e-47   9.4e-44       1     375 [.      27     418 ..      27     430 .. 0.88
   2 !   12.9   1.0   3.9e-06     0.035     385     424 ..     503     542 ..     473     543 .. 0.80

  Alignments for each domain:
  == domain 1  score: 149.9 bits;  conditional E-value: 1.1e-47
  AA_permease_2   1 lsllsafalvigsvigsgifvkn...laasggpalilwvwiavligslavllvyaElssalprsgGiyvytkaaf....gkkvaflsawfnwfayv 89 
                    ++++s+f++++  +i    + +    ++++ggp+ +l+++i++    l+v  v+ El+s+ p   G+y +++ ++      ++ ++ +w++ +a++
     EEA18680.1  27 FDFWSLFGFAVCELITWETVLALfsqGFENGGPSGLLYGFIIAWTSTLSVYTVISELASMAPIAAGQYYWVYMLSseryRVFASYIIGWLTSLAWI 122
                    79************7744333333349*******************9***************************7443367777************ PP

  AA_permease_2  90 pvlasilsvaasyllnal...gpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfsslstetdtf 182
                    +++a+ +  a+++l++++   +p+++ ++w+  l+ +a+ ++ +++n++ ++ + +i   ++++++ ++++i+ +l  +t +++ +++     ++ 
     EEA18680.1 123 ATVATESLFAGEMLQGLVtldFPTYTATRWQGTLLTWAVALVSTFVNAVIPSMLPRIEIGTVVFHVAGFVVIIALLWHYTPSFHNADF--VFRTSL 216
                    ***999988999997775444689999****************************************999999999999999988873..344467 PP

  AA_permease_2 183 fpngwpg....vllgllivlwsfdGfesaanvseevkk..kdvpkaifigllivlvlyllvniaflgvvpddeianlsnlgs.vaalffeavggkv 271
                    + +gwp+    + +g+l+ + +f+G +++++ +eev     ++p++i++++++ +++++ +++++l++++d      s++g  ++++f++ v + +
     EEA18680.1 217 NEGGWPTqglsYCVGFLGNVATFVGADASVHLAEEVSDapSTIPRVIISSMVLNGIVGFAMMLTLLFCLGDVDSVLASQTGFpFIQIFYNSVRSVA 312
                    777***75565799*********************8886679*****************************66644444454157********88* PP

  AA_permease_2 272 vaiivvilialsllgaintavigssrvlealardgvlP..rffakvn.kfgspiraiiltaivslillllfllassaaynfllsvsslgliisyll 364
                    +a+++ +++ +  + ++++ ++++sr+ +a+ard++ P    ++kv+ +++ pi a+ ++++++++l+l+  ++ss+a+n + s++  g++ syl+
     EEA18680.1 313 GATVMGAIVLILTWACATGIITSASRMTWAFARDRGTPfsGIISKVDpRTQVPIIAVGVVVTIACLLTLIN-VGSSTAFNDVISLTITGFYGSYLV 407
                    ***********************************************99***************9997555.5579******************** PP

  AA_permease_2 365 liigalilrkk 375
                    + +++l++r +
     EEA18680.1 408 PCALLLYHRLQ 418
                    ********965 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 3.9e-06
  AA_permease_2 385 ilvaiigalfllfllvalffppkgpatqssliytiiltva 424
                    i+ ++ ++++ +f++++  +pp++p+++++++y++++t++
     EEA18680.1 503 IINNAYACVYMVFVIFWSVWPPATPVATDTMNYSVVVTGG 542
                    566778899999999*********************9987 PP

>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.5  32.1   2.1e-26   1.9e-22      24     366 ..      55     391 ..      46     418 .. 0.85
   2 ?   -3.2   1.6      0.26   2.3e+03     420     464 ..     508     553 ..     499     560 .. 0.52

  Alignments for each domain:
  == domain 1  score: 79.5 bits;  conditional E-value: 2.1e-26
  AA_permease  24 sqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgp....elGfviGlnylfswitvlaleltaasiliqfwelvtdlpkawvt. 116
                   ++Gp g+l ++++a++ ++ v   ++e+a++ p ++g y+++    ++     +++ iG+++ + wi+++a e   a+ ++q +  + d p+  +t 
   EEA18680.1  55 ENGGPSGLLYGFIIAWTSTLSVYTVISELASMAPIAAGQYYWVYMLSSEryrvFASYIIGWLTSLAWIATVATESLFAGEMLQGL-VTLDFPTYTATr 151
                  689***********************************99988766665222268*******************99998888888.688888555559 PP

  AA_permease 117 ......gavflvvlliinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkgagfrflgdngsifknnlppgfakeeegafknfisvfviv 208
                           + +v +++n v   +  ++e+ + ++ +  ++  i ++ ++  + +++++  fr   ++g+    + ++g         ++ +++f   
   EEA18680.1 152 wqgtllTWAVALVSTFVNAVIPSMLPRIEIGTVVFHVAGFVVIIALLWHYTPSFHNADF-VFRTSLNEGG----WPTQG---------LSYCVGFLGN 235
                  9*643322222333445555556677889999999999999999999999999999999.8888888888....88888.........99******** PP

  AA_permease 209 vfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasaaspfvifikesgvsvlaplinaviltaalssans 306
                  v +f G  + + +a+Ev+d   +iP++i++ +++ +i+   ++l++ +++++ d  l +++  +   + if ++  + + a+++ a++l+ ++ +a +
   EEA18680.1 236 VATFVGADASVHLAEEVSDAPSTIPRVIISSMVLNGIVGFAMMLTLLFCLGDVDSVLASQTGFP--FIQIFYNSVRSVAGATVMGAIVLILTWACATG 331
                  ******************************************************9999988866..99999999999999****************** PP

  AA_permease 307 slysasRvlyslakdglaP...kvlkkvskrgvPlraillsmiisllalllaslnlaapivfn 366
                  +++sasR+ +++a+d+  P    + k+  + +vP+ a+ ++  i++l+ l++  ++    +fn
   EEA18680.1 332 IITSASRMTWAFARDRGTPfsgIISKVDPRTQVPIIAVGVVVTIACLLTLINVGSST---AFN 391
                  *******************9988889999*******************988765544...444 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 0.26
  AA_permease 420 aaliiillil..alyayltvkkgpkdwgaasfaaaylivllfliilv 464
                   a++ ++ +   ++++++t +   +++++++++   +i+l ++ ++v
   EEA18680.1 508 YACVYMVFVIfwSVWPPAT-PVATDTMNYSVVVTGGVIILSIVWYWV 553
                  4444433333003344444.444456666666666666666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (580 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       701  (0.0390987); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.32s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 3695.16
//
Query:       EEA18681.1  [L=641]
Description: serine palmitoyltransferase 1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.4e-60  205.4   0.0    1.9e-60  205.0   0.0    1.1  1  Aminotran_1_2  Aminotransferase class I and II
  ------ inclusion threshold ------
       0.49    8.3   2.0        0.7    7.8   2.0    1.1  1  Dicty_REP      Dictyostelium (Slime Mold) REP protein
        8.7    5.2   6.1         13    4.6   6.1    1.1  1  DUF5427        Family of unknown function (DUF5427)


Domain annotation for each model (and alignments):
>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  205.0   0.0   3.2e-64   1.9e-60       2     360 ..     227     580 ..     226     582 .. 0.96

  Alignments for each domain:
  == domain 1  score: 205.0 bits;  conditional E-value: 3.2e-64
                    EEEESSSSSTTSTTSS.HHHHHHHHHHHH..HHHHHTSTTST-BTTHHHHHHHHHHHHHCTCTTCHTTGGEGEEEESHHHHHHHHHHHHHHHTTT- CS
  Aminotran_1_2   2 dvinLgsneylgdsgk.ptlpevakaeke..galaggtlneygpidglpeleealakflgrseklklkreaavvvgsGagaliealifllklnpgd 94 
                    d +nL+s +ylg +++  ++ + a+ + +  g+ ++gt+    ++ ++ e+e ++a+f+g        +++a+v+++G+  ++ ++++l +  +g+
     EEA18681.1 227 DTLNLSSYNYLGFAQSeGPCADFAEDTLRksGITMTGTIGDAATSSLHVEVERQIARFVG--------KDDALVFSMGFVTNATIFPALVD--KGC 312
                    679*********************************************************........999*******************8..*** PP

                    EEEEEESS-THHHHHHHHTTSEEEEEEBEETTTTEE-HHHHHHHHTTHHCTTE.......TEEEEEEESS-TTT--B--HHHHHHHHHHHHHTTEE CS
  Aminotran_1_2  95 eilvpdptyasyknilrlsggevvryplyseedfhldlealeealkeapegnk.......ktkvilvesphNPtGtvatleeleklldlakkynll 183
                     il++++++as+  ++rlsg+ ++ ++       h+++ +le++l++a ++ +       k+ ++ ve+ +++ Gt+ +l+ + +l   +k+y+++
     EEA18681.1 313 LILSDELNHASIRFGARLSGASIQVFA-------HNNMADLEKKLRDAISQGQprthrpwKKILVTVEGLYSMEGTMVNLPGIMEL---KKRYRFY 398
                    ***************************.......****************************************************...******* PP

                    EEEEETTTTCBSSSSHTHHH....HGGSTTSTTEEEEEESSSTTSSGGG-EEEEEEEHHHHHHHHHHHHHHTS.SHHHHHHHHHHHHHHHHHHH.. CS
  Aminotran_1_2 184 lfvDeaYagfvfgsldavat....ranveeepnllivgslsKafGlaGeRvGyilgnaavvsqlrklsrpfls.ssllqaavaaalsdallkqs.. 272
                    l++Dea+++++ g+ +        +++v+++   +++g++ K+fG+ G   Gyi++++ +v+ lr   ++  +  s++++++a++l +  +++   
     EEA18681.1 399 LYIDEAHSVGAVGPRG---RgvcdYFKVDPANVEILMGTFTKSFGANG---GYIAADKIIVDKLRATCSGQAFgESPTPPVLAQILGALRQIAGee 488
                    *************652...13357******9889**************...*************************************99988787 PP

                    HHHHHHHHHHHHHHHHHHHHHHSTEEEECCS.CSSEEEEEETHHCHHHHHHHHHHTCTEEEEEGGGGTS...TTEEEEEC.TTS-HHHHHHHH CS
  Aminotran_1_2 273 eleemrqrlqkrrkelrdeLaelglkvlasq.sgmflltdlsaetakelskkLleevgvyvtpgtsftv...pgrlRitv.Aglteeeleelv 360
                      +e+ qrl  ++++lr +L++lg++v++ + s +++l++++++++ ++s ++l++ ++ v+ +t++ +    +r+R++v A++t+++l++l+
     EEA18681.1 489 MGKERLQRLVFNSRYLRLGLKRLGFIVYGHDdSPIIPLMLYNPAKMPAFSHEMLKR-KISVVVVTYPATpleLSRVRFCVsAAHTKADLDRLL 580
                    8999*************************999************************.99999999**99998899****************97 PP

>> Dicty_REP  Dictyostelium (Slime Mold) REP protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   2.0   0.00012       0.7     232     281 ..      49      98 ..      34     114 .. 0.70

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.00012
   Dicty_REP 232 ieqesiesentqrensqpskeknkttttttttttttsqartrkrkaiddd 281
                 ++++s +++  + ++ ++s  +++  ttttttttt s +   +r+a  d 
  EEA18681.1  49 STPISGNASSSSTNSNNDSGPETTAPTTTTTTTTTSSSPEDLRRQARRDA 98 
                 55556666665555555555666666677777777778888888877765 PP

>> DUF5427  Family of unknown function (DUF5427)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   6.1    0.0021        13      13      88 ..      10      88 ..       2     102 .. 0.51

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.0021
     DUF5427 13 vkkkkkkkktkkkkkakkkdeediLaeLe.eLakkesrpaTPrvksn.kskkaspkkkk..saeepakeekkkeeessed 88
                v+++k+++ + +++++ +++ + ++      L++ +srp+TP ++ n +s++ + ++++  ++++p++++++++++ss +
  EEA18681.1 10 VDSHKESDGKGNATSSPTTSAHALFSTVHdSLTTSHSRPSTP-ISGNaSSSSTNSNNDSgpETTAPTTTTTTTTTSSSPE 88
                445555555555555555555589999987999977******.5555333222222222443333333333322222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (641 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       797  (0.0444531); expected 358.6 (0.02)
Passed bias filter:                      587  (0.0327403); expected 358.6 (0.02)
Passed Vit filter:                        77  (0.00429472); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.68u 0.33s 00:00:01.01 Elapsed: 00:00:00.48
# Mc/sec: 4011.44
//
Query:       EEA18682.1  [L=354]
Description: proline racemase A precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
     1e-127  425.7   0.4   1.2e-127  425.5   0.4    1.0  1  Pro_racemase  Proline racemase


Domain annotation for each model (and alignments):
>> Pro_racemase  Proline racemase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  425.5   0.4  6.6e-132  1.2e-127       1     325 []       9     336 ..       9     336 .. 0.99

  Alignments for each domain:
  == domain 1  score: 425.5 bits;  conditional E-value: 6.6e-132
                   EEEEEETTEEEEEEEESS---SSSSHHHHHHHHHHH.HHHHHHHHSTTTS-TT-EEEEEE--SSTTSSEEEEEEESSSB-SSTHHHHHHHHHHHHHT CS
  Pro_racemase   1 vvdsHteGevgrvvvgGvpelpgetlaekrrlleedldalRralllePRGhdvmsgallvppkepdadlgvifletsgylpmcGsntigvvtvllet 97 
                   vv++H+eGevg+v+vgGv ++pg+t++ek r++e++ d+lR++ll+ePRG + m+++l++pp +p+ad+g++++e+++y pm+Gsnti+++tvllet
    EEA18682.1   9 VVGCHAEGEVGDVIVGGVLDVPGATMFEKLRHFETKKDDLRQFLLNEPRGRAPMNVNLVLPPCDPRADAGFLIMESNEYAPMSGSNTICTATVLLET 105
                   79*********************************************************************************************** PP

                   TSS-SEEEECEEEEEETTEEEEEEEECTSTSEEEEEEE-S-BEEEEEEEEEEETTTEEEEEEEEESSSEEEEEEGGGCTS-SSCCCHHHHHHHHHHH CS
  Pro_racemase  98 GlvevqepetklsletpaGlvevtaecrdgkvervslenvpsfvyaldvevevpglGkvkvDiayGGnfyaiveaeklgldlekaearelveagekl 194
                   G+++++ep t++ l+t+aGlv+vtaec++gk+++++++nv+sf+ +ld++v+vpg+G+++vDiayGG++y++v+a+++gl+++++ arelv++ge++
    EEA18682.1 106 GMIPMKEPVTEVALDTAAGLVTVTAECQGGKCKSIEFNNVASFALELDMKVDVPGVGEISVDIAYGGMMYVLVDAASVGLEIHNRFARELVDLGERI 202
                   ************************************************************************************************* PP

                   HHHHHHHH---TTCSTTC-SEEEEEEEEEETTTTS...EEEEEEEETTSEB-SS--HHHHHHHHHHHHHTTSS-TT-EEEEEETTS-EEEEEEEEEE CS
  Pro_racemase 195 realneqlkvqhpenedirevslveltgkkeraea...earnaviisdkkvDRSPcGtgtsArlAvlaakGklkvgeefvqesiiGseFegrveeea 288
                   ++a++  +k +hpen  i+++s+  +t++ + +e+   +a navi+s++++DRSPcGtgt Ar+Av++a+G+lk+ge f+++siiG+eF +r+ +++
    EEA18682.1 203 KRAVRVVYKPVHPENAGITGFSVLAFTAPVTVEEDgckAASNAVIVSPGRFDRSPCGTGTCARMAVMHARGELKEGEIFRHRSIIGTEFVSRIRGLT 299
                   *****************************999988787999******************************************************** PP

                   EECTCEEEEEEEEE-EEEEEEEEEEE-TT-TTTT-BX CS
  Pro_racemase 289 evggrkaivpeisGrafitglaqllldpsDPfaeGft 325
                   +vg+++a++p+++Gr++it+++q++ldpsDPf+eGf+
    EEA18682.1 300 TVGDYPAVLPTVKGRGWITAFKQVVLDPSDPFQEGFR 336
                   ***********************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (354 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       260  (0.0145016); expected 358.6 (0.02)
Passed bias filter:                      246  (0.0137208); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.24s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2548.83
//
Query:       EEA18683.1  [L=343]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.9e-17   62.9   0.0    6.8e-17   62.1   0.0    1.4  1  AAA              ATPase family associated with various cellul
    0.00066   20.0   0.6     0.0027   18.0   0.1    2.1  2  AAA_22           AAA domain
    0.00089   19.3   0.1     0.0034   17.4   0.1    2.1  1  AAA_5            AAA domain (dynein-related subfamily)
     0.0028   18.0   0.1      0.011   16.2   0.1    1.9  1  AAA_16           AAA ATPase domain
     0.0082   16.5   0.0      0.018   15.4   0.0    1.7  1  AAA_19           AAA domain
  ------ inclusion threshold ------
      0.015   15.4   0.0      0.032   14.3   0.0    1.6  1  Torsin           Torsin
      0.016   14.9   0.0      0.028   14.1   0.0    1.4  1  AAA_30           AAA domain
      0.053   13.2   0.0      0.093   12.4   0.0    1.4  1  Sigma54_activat  Sigma-54 interaction domain


Domain annotation for each model (and alignments):
>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.1   0.0     3e-20   6.8e-17       1     129 [.     119     237 ..     119     240 .. 0.89

  Alignments for each domain:
  == domain 1  score: 62.1 bits;  conditional E-value: 3e-20
                 EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTS CS
         AAA   1 vllyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksrsgseseeeervvnqLlteldgvkkk 99 
                 +ll+G pGtGKTl+a++va+ +  +++++ + ++     +e ek ++ ++         +++++DE+d + ++r ++++ +++ +v+++l++l+ ++  
  EEA18683.1 119 MLLHGGPGTGKTLTAESVAELTRKPLYRVTCGDIG-TNAEEVEKYLESVLLIGTIW--GCVVLLDEADVFLEER-RETDLQRNALVSVFLRVLEYYDG- 212
                 89********************************9.55666666676666544333..4***************.8999999**************99. PP

                 SSTEEEEEEESSGGGSTHHHHSTTSSEEEE CS
         AAA 100 eskvivigatnrpdkldpallrgRfdrkie 129
                     i+i+++nr+ ++d+a+  +Rf+  i+
  EEA18683.1 213 ----ILILTSNRIGTFDSAFK-SRFQLAIH 237
                 ....*****************.9**98876 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.1   1.2e-06    0.0027       4      53 ..     115     155 ..     111     169 .. 0.83
   2 ?   -0.9   0.0      0.79   1.8e+03      93     103 ..     175     186 ..     157     203 .. 0.73

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 1.2e-06
      AAA_22   4 tagilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstss 53 
                 +a i++++G +GtGKT++++ ++e           r+++++vt+   ++ 
  EEA18683.1 115 NALIMLLHGGPGTGKTLTAESVAELT---------RKPLYRVTCGDIGTN 155
                 6889********************99.........999999999776655 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.79
      AAA_22  93 elliiDEaqh.l 103
                  ++++DEa+  l
  EEA18683.1 175 CVVLLDEADVfL 186
                 68999**99844 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.1   1.5e-06    0.0034       2      45 ..     119     163 ..     118     232 .. 0.82

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 1.5e-06
                 EEEE--SSSSHHHHHHHGGGGBS--EEEEE--T.T--HHHHH--B CS
       AAA_5   2 vlLvGppGtgKselaerlaaalnreveyvqltr.dtteedlkgrr 45 
                 +lL G pGtgK+  ae++a+++++++  v + + +t++e++   +
  EEA18683.1 119 MLLHGGPGTGKTLTAESVAELTRKPLYRVTCGDiGTNAEEVEKYL 163
                 69********************99988777754266666666555 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.1   4.8e-06     0.011      22      52 ..     114     146 ..      98     207 .. 0.75

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 4.8e-06
      AAA_16  22 grpelvllsGesGvGKsslvrellralekd...g 52 
                 g   ++ll+G +G+GK+  +++++ +l+++   +
  EEA18683.1 114 GNALIMLLHGGPGTGKTLTAESVA-ELTRKplyR 146
                 44499*******************.577764541 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   7.8e-06     0.018       7      34 ..     113     140 ..     106     202 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 7.8e-06
      AAA_19   7 alkekvllvtaGpGtGKTrvlkhivall 34 
                 + ++ ++l+ +GpGtGKT + + + +l 
  EEA18683.1 113 KGNALIMLLHGGPGTGKTLTAESVAELT 140
                 5567789***********9988776654 PP

>> Torsin  Torsin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   1.4e-05     0.032      38      76 ..      99     139 ..      71     164 .. 0.70

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 1.4e-05
                 HHHHHHHHT-..SS-SS-EEEEEEE-TTSSHHHHHHHHHHH CS
      Torsin  38 vksvkaylen..ekpkkpLvlsfhGwtGtGknfvaeiiaen 76 
                 v+++ a  ++  e    +L++ +hG +GtGk   ae +ae 
  EEA18683.1  99 VHTISAKSTDiiEGKGNALIMLLHGGPGTGKTLTAESVAEL 139
                 444444433311345679***************99998875 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   1.3e-05     0.028      17      49 ..     115     147 ..     110     184 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 1.3e-05
      AAA_30  17 gdrvavltGpAGtGKttalkalreaweaaggrv 49 
                 ++++++l+G++GtGKt + ++++e+ ++  +rv
  EEA18683.1 115 NALIMLLHGGPGTGKTLTAESVAELTRKPLYRV 147
                 567899******************998876666 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   4.2e-05     0.093      22      63 ..     116     154 ..      92     170 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 4.2e-05
                      SS-EEEECSTTSSHHHHHHHHHHHSTTTTS-EEEEETTTS-T CS
  Sigma54_activat  22 dlsvlitGesGtGKellaraiheaskrkekpfvavncaaipe 63 
                       l +l++G  GtGK+l a+++ e ++   kp+ +v c++i +
       EEA18683.1 116 ALIMLLHGGPGTGKTLTAESVAELTR---KPLYRVTCGDIGT 154
                      467899**************998776...8999999999844 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (343 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       447  (0.0249317); expected 358.6 (0.02)
Passed bias filter:                      410  (0.022868); expected 358.6 (0.02)
Passed Vit filter:                        70  (0.00390429); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 2246.01
//
Query:       EEA18684.1  [L=396]
Description: hypothetical protein PMAA_009670 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (396 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       662  (0.0369234); expected 358.6 (0.02)
Passed bias filter:                      450  (0.025099); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.48u 0.24s 00:00:00.72 Elapsed: 00:00:00.39
# Mc/sec: 3029.22
//
Query:       EEA18685.1  [L=668]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.2e-09   37.8   0.1    3.6e-09   36.2   0.1    1.7  1  PNP_UDP_1  Phosphorylase superfamily
  ------ inclusion threshold ------
      0.077   12.4   0.0       0.16   11.3   0.0    1.5  1  ExoD       Exopolysaccharide synthesis, ExoD


Domain annotation for each model (and alignments):
>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2   0.1   4.1e-13   3.6e-09       1     183 [.       8     269 ..       8     306 .. 0.81

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 4.1e-13
                 CEEEEESSHHHHHHHHHHEEEEEEEEEE...TTEEEEEEEETTEEEEEEE--...SSHHHHHHHHHHHHHH.HC...--SEEEEEEEEEES.....STT CS
   PNP_UDP_1   1 kiaiivgspgevellaespleetpfgre..grgfkfvtGtlkgkpvvivstG...iGkpnaavvaeirllk.ef...gvkaiiriGtaGgl.....npd 85 
                 +i+ i++ p e+++  +    ++p  ++      ++++G+++ ++vvi++      G+++a     + +++ +f   ++   + +G+ Gg+     + d
  EEA18685.1   8 RIGWICALPLELAAAQAMLDRTHPQLPNaaADRNNYILGSIGAHNVVITCLPagvYGTTSAT----ATAIQmRFsyeSIQWCLLVGIGGGVgisgaKLD 102
                 58899****88888888855555555555559****************99994444555555....4444434433489999*********99998999 PP

                 T-TT-EEEEEEEEESSSCCGCCTHHCC......................................................................TC CS
   PNP_UDP_1  86 lkvGDvvipddainfdgrsplygpkee......................................................................gq 114
                 +++GDvv+ +  +++ g  ++ + k                                                                          
  EEA18685.1 103 IRLGDVVVCEPTVHYGGVIQYDYGKAVhggefvrtgtldkppevllkalarlqaqhmvhgstahlihqqvlkrypllqeefscpdpiedrlfvsdyyHR 201
                 ***********8776666665555444666677999*********************************************************987767 PP

                 CCCTTSSEE--HHHHHHHHHCHHTTTTTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHH CS
   PNP_UDP_1 115 yfpdsydapadpelrallkeaaealgikvhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaql 183
                  + d++ ++ dp++++   +   ++  +v +G++a+a+++  +++ +++l +r+g+ + eME+a v  +
  EEA18685.1 202 DASDPNCYKCDPAMLQSRYH-RTDNKTRVFYGLIASANQVIKDSKLRDELAQRYGILCFEMEAAGVMNV 269
                 77777777889999888777.6777799999*********************************99765 PP

>> ExoD  Exopolysaccharide synthesis, ExoD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   1.8e-05      0.16      51      82 ..       9      40 ..       1      42 [. 0.88

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 1.8e-05
        ExoD 51 vstifGllilllalqmllgrrtpwLPkklarr 82
                +++i++l++ l a+q +l r++p LP+  a+r
  EEA18685.1  9 IGWICALPLELAAAQAMLDRTHPQLPNAAADR 40
                6789***********************98887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (668 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       599  (0.0334096); expected 358.6 (0.02)
Passed bias filter:                      556  (0.0310112); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.32s 00:00:00.96 Elapsed: 00:00:00.46
# Mc/sec: 4370.58
//
Query:       EEA18686.1  [L=704]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.5e-34  115.6   7.8    8.5e-34  115.6   7.8    2.3  2  SAS4            Something about silencing, SAS, complex subun
     0.0066   17.1   1.5     0.0066   17.1   1.5    5.7  4  PEHE            PEHE domain


Domain annotation for each model (and alignments):
>> SAS4  Something about silencing, SAS, complex subunit 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.1       0.3   2.7e+03      51      74 ..     151     173 ..     142     180 .. 0.75
   2 !  115.6   7.8   9.4e-38   8.5e-34       1      98 [.     403     498 ..     403     499 .. 0.98

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.3
        SAS4  51 rvlgkitkindpkdkkelerkrel 74 
                 ++ g  t i+d + ++e e++r  
  EEA18686.1 151 KFFGGNT-IKDNNTRAETETQRPT 173
                 6666777.9999999999999865 PP

  == domain 2  score: 115.6 bits;  conditional E-value: 9.4e-38
        SAS4   1 DpLsDklYekaHkrmerqEkrmrniekeraesEadrlerllekLqgqdwlrvlgkitkindpkdkkelerkreltikeieallekferwkkeekklkk 98 
                 DpLsD++Y+kaH+r erqEk++rniekera++E+ +l+rll++Lqg+dwlrv+g+++ i+d ++kk +e+kr++++ke++al++kf+ wk+eek++k+
  EEA18686.1 403 DPLSDDVYFKAHRRHERQEKQLRNIEKERAQHEKIQLDRLLDELQGHDWLRVMGISG-ITD-TEKKLYEPKRDYFVKEVSALINKFHMWKEEEKRRKH 498
                 9*****************************************************999.***.*********************************986 PP

>> PEHE  PEHE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   2.8      0.53   4.8e+03      65     113 ..      61     108 ..      16     146 .. 0.68
   2 ?   -3.8   5.0         2   1.8e+04      61      61 ..     225     225 ..     159     317 .. 0.59
   3 !   17.1   1.5   7.4e-07    0.0066      11      62 ..     388     440 ..     383     455 .. 0.88
   4 ?  -11.5  17.6         2   1.8e+04      70     118 ..     566     626 ..     481     644 .. 0.71

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.53
        PEHE  65 keskkgrntpqpgsenpltkqppspddsesihvldevpvvasplpplsp 113
                 ++ ++gr++++++  + l++ ++ p+ + +  ++++ +  ++p+ ++s+
  EEA18686.1  61 QNPTNGRTVNTKKPRKMLATSKSLPNLMAHTINSTTSSI-KRPRISSST 108
                 333447788877777777888788877777333333333.333222222 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 2
        PEHE  61 l 61 
                 +
  EEA18686.1 225 V 225
                 2 PP

  == domain 3  score: 17.1 bits;  conditional E-value: 7.4e-07
        PEHE  11 lqslkeseeees.eiEdlSDeaFakRHaklEekerkRwdlqrnreqqrreslr 62 
                   +l++ e+++s  +  lSD+++ k H ++E++e++ + + + r+q+++ +l 
  EEA18686.1 388 KVELPKVEDSDSvVTDPLSDDVYFKAHRRHERQEKQLRNIEKERAQHEKIQLD 440
                 5577788888887789*******************************999865 PP

  == domain 4  score: -11.5 bits;  conditional E-value: 2
        PEHE  70 grntpqpgse..........npltkqppspddsesihvldevpvva..splpplspells.e 118
                 g++t++p+ +          ++lt+ pp+  + ++ +  ++ +v+a  + ++p+sp++++ e
  EEA18686.1 566 GATTSSPSTPahpqprrrlvDELTSTPPKSRSQHH-RTNSKQSVQAttNQASPTSPQTHHhE 626
                 44444444444445555555666666666666555.56666666666677777777775442 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (704 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1642  (0.0915835); expected 358.6 (0.02)
Passed bias filter:                      386  (0.0215294); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.86u 0.33s 00:00:01.19 Elapsed: 00:00:00.50
# Mc/sec: 4218.45
//
Query:       EEA18687.1  [L=640]
Description: hypothetical protein PMAA_009700 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
      0.012   15.8   0.6      0.033   14.4   0.1    2.0  2  TetR_C_31  Tetracyclin repressor-like, C-terminal domain


Domain annotation for each model (and alignments):
>> TetR_C_31  Tetracyclin repressor-like, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.1   1.8e-06     0.033      16      64 ..     350     399 ..     339     410 .. 0.81
   2 ?   -3.2   0.0      0.56     1e+04      49      69 ..     478     499 ..     472     507 .. 0.53

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.8e-06
                 CCCT.THHHHHHHHHHHHHHCCSCHHHHHHHHHHHHHHHHHHHHHHHHCS CS
   TetR_C_31  16 rala.drertlAryelfleaarrPeLraalarlrralrealaallaalGl 64 
                  + + + + +lA+ye+ l  + r eLr+++++++   ++++++l  al +
  EEA18687.1 350 WFSSqEDAKYLALYEMKLDVQTRQELRELADQTYVPAAAHWVRLKNALAS 399
                 333469999************************99988888888777776 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 0.56
                 HHHHHHHHHHHHHHCS.S-HHH CS
   TetR_C_31  49 ralrealaallaalGl.pdpee 69 
                  a+++a++ + +++ + p  ++
  EEA18687.1 478 KAFLDATEPVIRRAVSsPTRRA 499
                 4555555556665555333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (640 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       519  (0.0289475); expected 358.6 (0.02)
Passed bias filter:                      466  (0.0259914); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.27s 00:00:00.86 Elapsed: 00:00:00.42
# Mc/sec: 4524.22
//
Query:       EEA18688.1  [L=275]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.5e-08   33.7   0.3    6.7e-08   32.7   0.2    1.6  1  APH             Phosphotransferase enzyme family
    1.6e-05   24.6   0.0    2.4e-05   24.1   0.0    1.3  1  Choline_kinase  Choline/ethanolamine kinase


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.7   0.2   7.5e-12   6.7e-08      51     224 ..      65     235 ..      36     264 .. 0.69

  Alignments for each domain:
  == domain 1  score: 32.7 bits;  conditional E-value: 7.5e-12
                 T-.....B--B-CTTBS-EEETTEEEEEEE----EE-SSHHHHHHHHHHHHHHHHHHCCHHCH.-S.......TTTB-SHHCHTCCHHHHHHCHHHCCC CS
         APH  51 gv.....pvPevlagdtddeeigllfalieyvpgrsllrklsaaqlpellealgeflaalhqvdpa.......alpladflaqdlellrqlesatarll 137
                 +v     +vP+v+ +   ++e+g+ f+++ yvp + ll+ l+  +  ++  ++   +a+l q+++        + +++++l +d  ++  ++     ++
  EEA18688.1  65 DVnhsivRVPRVYRF--VQDELGRGFLFMDYVPVQKLLD-LDLTVHTDITPRITNIIAHLGQIRHGqrpgpigEKGPQGYLWSDDGVDKPFV-----SI 155
                 33333379******7..77777777**************.6666666666666666666666653301122333333344433333444444.....44 PP

                 GCCTCCHHHHHHHHHHHHHHHH--SSS-EEEE-SS-SGGGEEEC..TTEEEEE---TT-EEEECCHHHHCCH.HHCSCHCCCHCHHHH CS
         APH 138 aselldlleeleeqvlaalaallpgelptvllHgDlhpgNllvdpddgrvtGviDfedaglgpplyDlavll.rswtseldpeflaal 224
                 a++++  l+++ + +++   +l p   p vl+H Dl  +N+ +  +d + ++++D+  ag   + y+ a l+ +   ++ d+ + + l
  EEA18688.1 156 AHLNRY-LIKRLS-LRNDSIDLSP--YPLVLCHMDLVRRNMRLG-EDKKAIYLLDWAHAGFFLRFYEPAALPcM---NPYDEPYEKSL 235
                 666666.666777.7788888888..9*****************.556666*****************999943...44444444333 PP

>> Choline_kinase  Choline/ethanolamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.0   2.6e-09   2.4e-05     137     197 ..     172     232 ..     148     248 .. 0.81

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 2.6e-09
                     HHHCHGG-EEEE-S--SGGGEEE.-CTTEEEE--GTT-EEEEHHHHHHHHHHHTTEEHHHC CS
  Choline_kinase 137 lleelespvvfcHnDlqegNillnkeekklvlIDFEYagynyrgfDlanhfiEwagdyeee 197
                      ++ + +p+v+cH Dl+ +N+ l +++k ++l D+  ag+  r ++ a   +   +d+ +e
      EEA18688.1 172 SIDLSPYPLVLCHMDLVRRNMRLGEDKKAIYLLDWAHAGFFLRFYEPAALPCMNPYDEPYE 232
                     45677889************************************99888777666665555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       275  (0.0153383); expected 358.6 (0.02)
Passed bias filter:                      264  (0.0147247); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.39s 00:00:00.96 Elapsed: 00:00:00.57
# Mc/sec: 1454.48
//
Query:       EEA18689.1  [L=1081]
Description: kinesin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.6e-88  288.5  14.3    8.9e-13   47.7   0.1    9.4  9  TPR_10     Tetratricopeptide repeat
    1.4e-67  223.9  11.8    5.2e-16   58.7   0.0    7.5  8  TPR_12     Tetratricopeptide repeat
    2.1e-30  102.5   7.8      0.004   17.1   0.0    9.1  9  TPR_7      Tetratricopeptide repeat
    6.2e-19   67.0   8.0      0.072   12.9   0.0    8.6  8  TPR_1      Tetratricopeptide repeat
    6.2e-18   63.4   7.6       0.12   12.5   0.0    8.8  8  TPR_2      Tetratricopeptide repeat
    4.6e-14   52.7   1.6       0.79   10.3   0.0    8.2  8  TPR_19     Tetratricopeptide repeat
    5.1e-13   48.1  13.2       0.38   11.1   0.1    8.5  8  TPR_8      Tetratricopeptide repeat
    7.3e-12   45.0   0.0    1.6e-11   43.9   0.0    1.5  1  PNP_UDP_1  Phosphorylase superfamily
    5.2e-09   35.9  20.5    3.1e-05   23.5   3.5    3.8  3  TPR_MalT   MalT-like TPR region
    1.7e-08   34.0   0.0    4.8e-08   32.5   0.0    1.7  2  NB-ARC     NB-ARC domain
    9.5e-08   32.0   0.0         30    5.6   0.0    7.1  6  TPR_4      Tetratricopeptide repeat
    1.8e-07   31.0   0.1       0.24   11.4   0.0    6.0  6  TPR_3      Tetratricopeptide repeat
    2.3e-07   30.7  13.8        8.2    7.1   0.0    8.3  8  TPR_17     Tetratricopeptide repeat
    5.3e-07   30.2   4.1        6.2    7.6   0.0    7.6  6  TPR_16     Tetratricopeptide repeat
    3.2e-06   27.7   0.1    3.8e-05   24.1   0.0    2.7  1  AAA_16     AAA ATPase domain
    1.3e-05   25.2   0.0    3.3e-05   23.9   0.0    1.7  1  NACHT      NACHT domain
    0.00026   21.6   4.2         74    4.6   0.0    7.4  7  TPR_14     Tetratricopeptide repeat
     0.0011   19.2   5.9        4.6    7.5   0.0    5.4  5  ANAPC3     Anaphase-promoting complex, cyclosome, subunit 3
     0.0047   16.9   0.0      0.011   15.7   0.0    1.6  1  ATPase_2   ATPase domain predominantly from Archaea
     0.0063   16.8   0.0      0.017   15.4   0.0    1.7  1  AAA_22     AAA domain
     0.0097   16.2   1.9         51    4.3   0.0    5.7  6  DUF4074    Domain of unknown function (DUF4074)
  ------ inclusion threshold ------
      0.016   14.9   0.0      0.035   13.7   0.0    1.6  1  SRP54      SRP54-type protein, GTPase domain
        0.1   12.0   0.0       0.21   11.0   0.0    1.5  1  ParA       NUBPL iron-transfer P-loop NTPase
       0.12   11.8   0.1        5.7    6.4   0.0    2.9  2  KdpD       Osmosensitive K+ channel His kinase sensor domain
       0.12   12.9   0.0       0.37   11.3   0.0    1.9  1  AAA_18     AAA domain
       0.31   11.4   3.7        3.6    8.0   0.0    3.6  3  RPN6_N     26S proteasome regulatory subunit RPN6 N-terminal 
       0.52    9.8   8.7        6.3    6.4   0.4    4.7  5  DUF1897    Domain of unknown function (DUF1897)
        2.1    8.3   7.0         13    5.7   0.1    4.6  6  CutA1      CutA1 divalent ion tolerance protein


Domain annotation for each model (and alignments):
>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.1       2.2   1.4e+03      20      33 ..     501     514 ..     498     516 .. 0.80
   2 !   10.4   0.0   0.00072      0.46       7      38 ..     727     758 ..     722     761 .. 0.87
   3 !   40.4   0.1   2.7e-13   1.7e-10       1      42 []     763     804 ..     763     804 .. 0.98
   4 !   37.6   0.0     2e-12   1.3e-09       1      41 [.     805     845 ..     805     846 .. 0.98
   5 !   32.8   0.1   6.8e-11   4.4e-08       1      42 []     847     888 ..     847     888 .. 0.97
   6 !   40.2   0.0     3e-13   1.9e-10       1      42 []     889     930 ..     889     930 .. 0.99
   7 !   47.7   0.1   1.4e-15   8.9e-13       1      42 []     931     972 ..     931     972 .. 0.99
   8 !   42.2   0.0   7.1e-14   4.5e-11       1      42 []     973    1014 ..     973    1014 .. 0.98
   9 !   37.9   0.0   1.6e-12     1e-09       1      41 [.    1015    1055 ..    1015    1056 .. 0.98

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 2.2
      TPR_10  20 eAealleealairr 33 
                  A+++le++la+ +
  EEA18689.1 501 TAVKILEKTLARKE 514
                 599*******9854 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00072
      TPR_10   7 NLanalrqrgrydeAealleealairrrllGp 38 
                 N+a  l++ gry+eAe ++++ + i ++  Gp
  EEA18689.1 727 NIATCLFSDGRYQEAEVFYRKLMTINQEKAGP 758
                 88888999****************99887665 PP

  == domain 3  score: 40.4 bits;  conditional E-value: 2.7e-13
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t++s+  La ++r++gr++eAe+l  +++++ r++lG+dH d
  EEA18689.1 763 TLTSMASLASTYRHQGRWNEAEELEVQVMETSRAVLGADHSD 804
                 89**************************************76 PP

  == domain 4  score: 37.6 bits;  conditional E-value: 2e-12
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHP 41 
                 t++s+ NLa +++++gr++e+e+l  +++++r   lG++HP
  EEA18689.1 805 TLNSMANLASTYWNQGRWNESEKLDMQVMEMRTTMLGTEHP 845
                 89**************************************9 PP

  == domain 5  score: 32.8 bits;  conditional E-value: 6.8e-11
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t++s+  La +++++gr++eAe+l+ ++++ir   lG++H d
  EEA18689.1 847 TLTSMASLALTYQNQGRWNEAEELFVQVMEIRMTMLGAEHLD 888
                 89************************************9976 PP

  == domain 6  score: 40.2 bits;  conditional E-value: 3e-13
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t++++ NLa ++ ++gr++eAe+l ++++++ + +lG +HPd
  EEA18689.1 889 TLNTMANLASTYLSQGRWTEAEKLDIQVMETFKTVLGVEHPD 930
                 89***************************************9 PP

  == domain 7  score: 47.7 bits;  conditional E-value: 1.4e-15
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t++++ NLa a+r++gry+eAe+l  +++++r+ +lG++HPd
  EEA18689.1 931 TLTIMANLASAYRSQGRYNEAEKLEGQVMETRKTVLGAEHPD 972
                 89***************************************9 PP

  == domain 8  score: 42.2 bits;  conditional E-value: 7.1e-14
      TPR_10    1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42  
                  t++s  NLa +++++gr+ eAe+l +++++i +++lG dHP+
  EEA18689.1  973 TLASIANLASTYWNQGRLSEAEKLEIQVMEISKAALGVDHPN 1014
                  899**************************************5 PP

  == domain 9  score: 37.9 bits;  conditional E-value: 1.6e-12
      TPR_10    1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHP 41  
                  t++s+ NLa++  ++g+++ A+al +++ ++r r+lGp+HP
  EEA18689.1 1015 TLTSMANLACTWKSQGKLQNALALIKQCADLRNRVLGPNHP 1055
                  89**************************************9 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.1      0.85   5.5e+02      21      52 ..     501     530 ..     499     533 .. 0.85
   2 !   47.9   0.1   1.9e-15   1.2e-12       6      74 ..     725     793 ..     721     796 .. 0.93
   3 !   45.6   0.1     1e-14   6.5e-12       9      76 ..     770     837 ..     770     838 .. 0.97
   4 !   53.2   0.0   4.2e-17   2.7e-14       4      75 ..     807     878 ..     804     880 .. 0.93
   5 !   58.7   0.0     8e-19   5.2e-16       3      76 ..     890     963 ..     888     964 .. 0.93
   6 !   22.5   0.0   1.6e-07    0.0001      28      74 ..     957    1003 ..     956    1003 .. 0.91
   7 !   32.7   0.1   1.1e-10   6.8e-08       2      53 ..     974    1024 ..     972    1028 .. 0.94
   8 !   17.9   0.0   4.4e-06    0.0028      16      56 ..    1029    1069 ..    1026    1072 .. 0.93

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.85
      TPR_12  21 eAlellekaleiarrllGpdhpltattlrnLg 52 
                  A ++lek l++ + l   d   ta+ l  L+
  EEA18689.1 501 TAVKILEKTLARKELL--RDTTTTAALLEQLA 530
                 69999****9999988..77777999999987 PP

  == domain 2  score: 47.9 bits;  conditional E-value: 1.9e-15
      TPR_12   6 lnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealai 74 
                   n+a++l+  gry+eA+ +++k + i ++  Gp+   t+t++  L+ +yr +gr+ eA+el  ++++ 
  EEA18689.1 725 IENIATCLFSDGRYQEAEVFYRKLMTINQEKAGPQDRSTLTSMASLASTYRHQGRWNEAEELEVQVMET 793
                 449**********************************************************98888775 PP

  == domain 3  score: 45.6 bits;  conditional E-value: 1e-14
      TPR_12   9 laavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                 la+++r++gr+ eA+el  +++e  r++lG dh +t++++ nL+ +y+ +gr+ e ++l  +++++++
  EEA18689.1 770 LASTYRHQGRWNEAEELEVQVMETSRAVLGADHSDTLNSMANLASTYWNQGRWNESEKLDMQVMEMRT 837
                 89*************************************************************99985 PP

  == domain 4  score: 53.2 bits;  conditional E-value: 4.2e-17
      TPR_12   4 talnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaia 75 
                 +++ nla++++ +gr+ e+++l  +++e+++  lG++hplt+t++  L+ +y+ +gr+ eA+el+ ++++i+
  EEA18689.1 807 NSMANLASTYWNQGRWNESEKLDMQVMEMRTTMLGTEHPLTLTSMASLALTYQNQGRWNEAEELFVQVMEIR 878
                 4444**************************999************************************997 PP

  == domain 5  score: 58.7 bits;  conditional E-value: 8e-19
      TPR_12   3 atalnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                 ++++ nla++++ +gr++eA++l  +++e ++ +lG +hp+t+t++ nL+ +yr +gry eA++l  ++++ ++
  EEA18689.1 890 LNTMANLASTYLSQGRWTEAEKLDIQVMETFKTVLGVEHPDTLTIMANLASAYRSQGRYNEAEKLEGQVMETRK 963
                 45555************************************************************999998765 PP

  == domain 6  score: 22.5 bits;  conditional E-value: 1.6e-07
      TPR_12   28 kaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealai 74  
                  +++e ++ +lG +hp+t+++  nL+ +y+ +gr+ eA++l  ++++i
  EEA18689.1  957 QVMETRKTVLGAEHPDTLASIANLASTYWNQGRLSEAEKLEIQVMEI 1003
                  578899999*****************************998777765 PP

  == domain 7  score: 32.7 bits;  conditional E-value: 1.1e-10
      TPR_12    2 vatalnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgr 53  
                  +a+++ nla++++ +gr+ eA++l  +++ei +++lG dhp+t+t++ nL+ 
  EEA18689.1  974 LASIA-NLASTYWNQGRLSEAEKLEIQVMEISKAALGVDHPNTLTSMANLAC 1024
                  46777.********************************************96 PP

  == domain 8  score: 17.9 bits;  conditional E-value: 4.4e-06
      TPR_12   16 lgrydeAlellekaleiarrllGpdhpltattlrnLgrlyr 56  
                  +g+++ Al+l +++ ++++r+lGp+hp   +t  +Lg++  
  EEA18689.1 1029 QGKLQNALALIKQCADLRNRVLGPNHPRSKSTSLALGDWMA 1069
                  8************************************9865 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       7.9     5e+03      15      31 ..     499     513 ..     498     516 .. 0.79
   2 !    9.6   0.0    0.0015      0.98       3      28 ..     726     751 ..     724     759 .. 0.82
   3 !   10.4   0.0   0.00083      0.53       3      21 ..     768     786 ..     766     800 .. 0.84
   4 !    9.0   0.0    0.0024       1.5       2      21 ..     809     828 ..     808     841 .. 0.82
   5 !   17.1   0.0   6.2e-06     0.004       3      34 ..     852     883 ..     850     885 .. 0.86
   6 !   14.4   0.0   4.4e-05     0.028       2      27 ..     893     918 ..     892     927 .. 0.82
   7 !   14.4   0.1   4.4e-05     0.028       3      34 ..     936     967 ..     934     969 .. 0.83
   8 !    9.3   0.0    0.0019       1.2       2      21 ..     977     996 ..     976    1010 .. 0.85
   9 !   12.8   0.0   0.00015     0.096       2      35 ..    1019    1052 ..    1018    1053 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 7.9
       TPR_7  15 yeeAielyeqsLaltkd 31 
                  e+A++++e+   l++ 
  EEA18689.1 499 KETAVKILEK--TLARK 513
                 589*******..77765 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.0015
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLal 28 
                  n+a + +++G+y+eA+ +y++++ +
  EEA18689.1 726 ENIATCLFSDGRYQEAEVFYRKLMTI 751
                 599*******************4444 PP

  == domain 3  score: 10.4 bits;  conditional E-value: 0.00083
       TPR_7   3 lnLarlysrlGdyeeAiel 21 
                   La++y+ +G++ eA+el
  EEA18689.1 768 ASLASTYRHQGRWNEAEEL 786
                 67***************98 PP

  == domain 4  score: 9.0 bits;  conditional E-value: 0.0024
       TPR_7   2 LlnLarlysrlGdyeeAiel 21 
                   nLa++y ++G++ e ++l
  EEA18689.1 809 MANLASTYWNQGRWNESEKL 828
                 57*************99887 PP

  == domain 5  score: 17.1 bits;  conditional E-value: 6.2e-06
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLaltkdped 34 
                   La +y+++G++ eA+el+ q+++++   ++
  EEA18689.1 852 ASLALTYQNQGRWNEAEELFVQVMEIRMTMLG 883
                 579*******************9998877666 PP

  == domain 6  score: 14.4 bits;  conditional E-value: 4.4e-05
       TPR_7   2 LlnLarlysrlGdyeeAielyeqsLa 27 
                   nLa++y ++G++ eA++l  q+++
  EEA18689.1 893 MANLASTYLSQGRWTEAEKLDIQVME 918
                 57*****************9888665 PP

  == domain 7  score: 14.4 bits;  conditional E-value: 4.4e-05
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLaltkdped 34 
                  nLa++y+++G+y eA++l  q+++++k  ++
  EEA18689.1 936 ANLASAYRSQGRYNEAEKLEGQVMETRKTVLG 967
                 69***************998887777776665 PP

  == domain 8  score: 9.3 bits;  conditional E-value: 0.0019
       TPR_7   2 LlnLarlysrlGdyeeAiel 21 
                 + nLa++y ++G+ +eA++l
  EEA18689.1 977 IANLASTYWNQGRLSEAEKL 996
                 78***************987 PP

  == domain 9  score: 12.8 bits;  conditional E-value: 0.00015
       TPR_7    2 LlnLarlysrlGdyeeAielyeqsLaltkdpeda 35  
                    nLa ++ ++G+ ++A+ l +q+  l+++ +++
  EEA18689.1 1019 MANLACTWKSQGKLQNALALIKQCADLRNRVLGP 1052
                  57**********************9999988775 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.9   0.0   0.00011     0.072       6      31 ..     727     752 ..     726     755 .. 0.89
   2 ?    5.1   0.0     0.033        21       6      22 ..     769     785 ..     766     786 .. 0.91
   3 ?    2.9   0.0      0.17   1.1e+02       5      22 ..     810     827 ..     807     828 .. 0.87
   4 !   11.8   0.0   0.00027      0.17       6      30 ..     853     877 ..     850     878 .. 0.90
   5 !    6.8   0.0    0.0096       6.1       5      22 ..     894     911 ..     891     912 .. 0.91
   6 !   12.0   0.2   0.00022      0.14       6      22 ..     937     953 ..     934     954 .. 0.92
   7 ?    5.7   0.0     0.022        14       6      22 ..     979     995 ..     976     996 .. 0.93
   8 ?    5.1   0.1     0.033        21       6      28 ..    1021    1043 ..    1018    1046 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 0.00011
                 HHHHHHHHTT-HHHHHHHHHHHHHHS CS
       TPR_1   6 nlGnayfklgkydeAleyyekALeln 31 
                 n++ ++f+ g+y+eA+ +y+k  ++n
  EEA18689.1 727 NIATCLFSDGRYQEAEVFYRKLMTIN 752
                 89******************977666 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.033
                 HHHHHHHHTT-HHHHHH CS
       TPR_1   6 nlGnayfklgkydeAle 22 
                  l+ +y+++g+++eA+e
  EEA18689.1 769 SLASTYRHQGRWNEAEE 785
                 5899***********98 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.17
                 HHHHHHHHHTT-HHHHHH CS
       TPR_1   5 ynlGnayfklgkydeAle 22 
                  nl+ +y ++g+++e ++
  EEA18689.1 810 ANLASTYWNQGRWNESEK 827
                 59***********99765 PP

  == domain 4  score: 11.8 bits;  conditional E-value: 0.00027
                 HHHHHHHHTT-HHHHHHHHHHHHHH CS
       TPR_1   6 nlGnayfklgkydeAleyyekALel 30 
                  l+++y+++g+++eA+e + ++ e+
  EEA18689.1 853 SLALTYQNQGRWNEAEELFVQVMEI 877
                 59*****************998877 PP

  == domain 5  score: 6.8 bits;  conditional E-value: 0.0096
                 HHHHHHHHHTT-HHHHHH CS
       TPR_1   5 ynlGnayfklgkydeAle 22 
                  nl+ +y+++g++ eA++
  EEA18689.1 894 ANLASTYLSQGRWTEAEK 911
                 69**************97 PP

  == domain 6  score: 12.0 bits;  conditional E-value: 0.00022
                 HHHHHHHHTT-HHHHHH CS
       TPR_1   6 nlGnayfklgkydeAle 22 
                 nl+ ay+++g+y+eA++
  EEA18689.1 937 NLASAYRSQGRYNEAEK 953
                 9**************97 PP

  == domain 7  score: 5.7 bits;  conditional E-value: 0.022
                 HHHHHHHHTT-HHHHHH CS
       TPR_1   6 nlGnayfklgkydeAle 22 
                 nl+ +y ++g++ eA++
  EEA18689.1 979 NLASTYWNQGRLSEAEK 995
                 9**************97 PP

  == domain 8  score: 5.1 bits;  conditional E-value: 0.033
                  HHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_1    6 nlGnayfklgkydeAleyyekAL 28  
                  nl+ +  ++gk++ Al+  +++ 
  EEA18689.1 1021 NLACTWKSQGKLQNALALIKQCA 1043
                  9***************9988875 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.8   0.0   0.00066      0.42       6      31 ..     727     752 ..     723     755 .. 0.89
   2 ?    5.7   0.0     0.029        19       7      22 ..     770     785 ..     766     786 .. 0.89
   3 ?    4.2   0.0     0.086        55       5      22 ..     810     827 ..     807     828 .. 0.88
   4 !   12.5   0.0   0.00019      0.12       7      30 ..     854     877 ..     850     880 .. 0.90
   5 ?    5.9   0.0     0.025        16       5      22 ..     894     911 ..     891     912 .. 0.90
   6 !    9.9   0.1    0.0014      0.87       5      22 ..     936     953 ..     933     954 .. 0.90
   7 ?    5.0   0.0     0.047        30       6      22 ..     979     995 ..     976     996 .. 0.91
   8 ?    4.3   0.0     0.085        54       5      30 ..    1020    1045 ..    1017    1048 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00066
       TPR_2   6 nlGlayyklgdyeeAleafekAleld 31 
                 n++ +++  g+y+eA+ +++k   ++
  EEA18689.1 727 NIATCLFSDGRYQEAEVFYRKLMTIN 752
                 8899*****************98887 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.029
       TPR_2   7 lGlayyklgdyeeAle 22 
                 l+  y+++g+++eA+e
  EEA18689.1 770 LASTYRHQGRWNEAEE 785
                 8999**********98 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.086
       TPR_2   5 ynlGlayyklgdyeeAle 22 
                  nl+  y+++g+++e ++
  EEA18689.1 810 ANLASTYWNQGRWNESEK 827
                 699************987 PP

  == domain 4  score: 12.5 bits;  conditional E-value: 0.00019
       TPR_2   7 lGlayyklgdyeeAleafekAlel 30 
                 l+l y ++g+++eA+e+f ++ e+
  EEA18689.1 854 LALTYQNQGRWNEAEELFVQVMEI 877
                 89****************999887 PP

  == domain 5  score: 5.9 bits;  conditional E-value: 0.025
       TPR_2   5 ynlGlayyklgdyeeAle 22 
                  nl+  y+ +g++ eA++
  EEA18689.1 894 ANLASTYLSQGRWTEAEK 911
                 699*************98 PP

  == domain 6  score: 9.9 bits;  conditional E-value: 0.0014
       TPR_2   5 ynlGlayyklgdyeeAle 22 
                  nl+ ay+ +g+y+eA++
  EEA18689.1 936 ANLASAYRSQGRYNEAEK 953
                 69**************98 PP

  == domain 7  score: 5.0 bits;  conditional E-value: 0.047
       TPR_2   6 nlGlayyklgdyeeAle 22 
                 nl+  y+++g++ eA++
  EEA18689.1 979 NLASTYWNQGRLSEAEK 995
                 89*************98 PP

  == domain 8  score: 4.3 bits;  conditional E-value: 0.085
       TPR_2    5 ynlGlayyklgdyeeAleafekAlel 30  
                   nl++ +  +g+++ Al++ +++  l
  EEA18689.1 1020 ANLACTWKSQGKLQNALALIKQCADL 1045
                  599*****************999877 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.0     0.014       8.9      23      56 ..     720     753 ..     716     757 .. 0.82
   2 !    9.1   0.0    0.0028       1.8       1      47 [.     732     786 ..     732     796 .. 0.78
   3 ?    1.9   0.0      0.52   3.3e+02      21      47 ..     802     828 ..     777     835 .. 0.77
   4 ?    3.2   0.0      0.19   1.2e+02      31      52 ..     854     875 ..     849     879 .. 0.84
   5 !    9.7   0.0    0.0019       1.2       4      47 ..     861     912 ..     860     920 .. 0.76
   6 !   10.3   0.0    0.0012      0.79      20      47 ..     927     954 ..     914     964 .. 0.84
   7 !    8.8   0.0    0.0036       2.3      19      47 ..     968     996 ..     957    1004 .. 0.91
   8 ?    0.4   0.0       1.5   9.9e+02       4      19 ..    1029    1044 ..    1028    1057 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.014
      TPR_19  23 knaearllLAeallalgqldeAealLdalpeedp 56 
                 +++++  + A +l++ g+++eAe    +l+  ++
  EEA18689.1 720 NYLDLIENIATCLFSDGRYQEAEVFYRKLMTINQ 753
                 67777778899************99988887666 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.0028
      TPR_19   1 llaegdyaeAlalleqalqedpk........naearllLAeallalgqldeAeal 47 
                 l+ +g+y+eA  +++++++ + +         +   + LA  +  +g+++eAe+l
  EEA18689.1 732 LFSDGRYQEAEVFYRKLMTINQEkagpqdrsTLTSMASLASTYRHQGRWNEAEEL 786
                 5779************99774444445454444555588**************96 PP

  == domain 3  score: 1.9 bits;  conditional E-value: 0.52
      TPR_19  21 dpknaearllLAeallalgqldeAeal 47 
                   + ++  ++LA  ++++g+++e e+l
  EEA18689.1 802 HSDTLNSMANLASTYWNQGRWNESEKL 828
                 55566667789**********998875 PP

  == domain 4  score: 3.2 bits;  conditional E-value: 0.19
      TPR_19  31 LAeallalgqldeAealLdalp 52 
                 LA  + ++g+++eAe+l  +++
  EEA18689.1 854 LALTYQNQGRWNEAEELFVQVM 875
                 788999**********987766 PP

  == domain 5  score: 9.7 bits;  conditional E-value: 0.0019
      TPR_19   4 egdyaeAlalleqalqe........dpknaearllLAeallalgqldeAeal 47 
                 +g+  eA +l+ q+++           + ++  ++LA  +l++g+++eAe+l
  EEA18689.1 861 QGRWNEAEELFVQVMEIrmtmlgaeHLDTLNTMANLASTYLSQGRWTEAEKL 912
                 788889999999988665555532234466666788*************986 PP

  == domain 6  score: 10.3 bits;  conditional E-value: 0.0012
      TPR_19  20 edpknaearllLAeallalgqldeAeal 47 
                 e p+ + + ++LA a+ ++g+++eAe+l
  EEA18689.1 927 EHPDTLTIMANLASAYRSQGRYNEAEKL 954
                 48999999******************97 PP

  == domain 7  score: 8.8 bits;  conditional E-value: 0.0036
      TPR_19  19 qedpknaearllLAeallalgqldeAeal 47 
                 +e p+ ++  ++LA  ++++g+l eAe+l
  EEA18689.1 968 AEHPDTLASIANLASTYWNQGRLSEAEKL 996
                 689999999******************86 PP

  == domain 8  score: 0.4 bits;  conditional E-value: 1.5
      TPR_19    4 egdyaeAlalleqalq 19  
                  +g++++Alal +q  +
  EEA18689.1 1029 QGKLQNALALIKQCAD 1044
                  89********999754 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.5   0.0   0.00088      0.57       6      32 ..     727     753 ..     722     755 .. 0.90
   2 ?    0.2   0.0       1.8   1.2e+03       4      22 ..     767     785 ..     764     786 .. 0.85
   3 ?    4.3   0.0     0.088        56       3      22 ..     808     827 ..     806     836 .. 0.82
   4 ?    6.1   0.0     0.023        15       4      30 ..     851     877 ..     848     878 .. 0.89
   5 ?    2.4   0.0      0.36   2.3e+02       4      22 ..     893     911 ..     890     912 .. 0.85
   6 !   11.1   0.1    0.0006      0.38       3      22 ..     934     953 ..     932     954 .. 0.90
   7 !    8.9   0.1     0.003       1.9       5      22 ..     978     995 ..     974    1006 .. 0.85
   8 ?    4.8   0.1     0.061        39       3      31 ..    1018    1046 ..    1016    1048 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00088
                 HHHHHHHHTT-HHHHHHHHHHHHHHHH CS
       TPR_8   6 nlgsiylklgdyeeAkeyyekaleldp 32 
                 n++ ++++ g+y+eA+ +y+k  ++++
  EEA18689.1 727 NIATCLFSDGRYQEAEVFYRKLMTINQ 753
                 8999*******************9997 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 1.8
                 HHHHHHHHHHTT-HHHHHH CS
       TPR_8   4 yynlgsiylklgdyeeAke 22 
                 +  l+s+y+ +g+ +eA+e
  EEA18689.1 767 MASLASTYRHQGRWNEAEE 785
                 6789*********999987 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.088
                 HHHHHHHHHHHTT-HHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAke 22 
                 ++ nl+s+y+++g+ +e+++
  EEA18689.1 808 SMANLASTYWNQGRWNESEK 827
                 679**********9777665 PP

  == domain 4  score: 6.1 bits;  conditional E-value: 0.023
                 HHHHHHHHHHTT-HHHHHHHHHHHHHH CS
       TPR_8   4 yynlgsiylklgdyeeAkeyyekalel 30 
                 +  l+++y+++g+ +eA+e + ++ e+
  EEA18689.1 851 MASLALTYQNQGRWNEAEELFVQVMEI 877
                 6789*****************999987 PP

  == domain 5  score: 2.4 bits;  conditional E-value: 0.36
                 HHHHHHHHHHTT-HHHHHH CS
       TPR_8   4 yynlgsiylklgdyeeAke 22 
                 + nl+s+yl++g+  eA++
  EEA18689.1 893 MANLASTYLSQGRWTEAEK 911
                 689*********9888875 PP

  == domain 6  score: 11.1 bits;  conditional E-value: 0.0006
                 HHHHHHHHHHHTT-HHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAke 22 
                 ++ nl+s+y+++g+y+eA++
  EEA18689.1 934 IMANLASAYRSQGRYNEAEK 953
                 678***************97 PP

  == domain 7  score: 8.9 bits;  conditional E-value: 0.003
                 HHHHHHHHHTT-HHHHHH CS
       TPR_8   5 ynlgsiylklgdyeeAke 22 
                  nl+s+y+++g++ eA++
  EEA18689.1 978 ANLASTYWNQGRLSEAEK 995
                 79**************98 PP

  == domain 8  score: 4.8 bits;  conditional E-value: 0.061
                  HHHHHHHHHHHTT-HHHHHHHHHHHHHHH CS
       TPR_8    3 ayynlgsiylklgdyeeAkeyyekaleld 31  
                  ++ nl+++ +++g++++A + ++++ +l+
  EEA18689.1 1018 SMANLACTWKSQGKLQNALALIKQCADLR 1046
                  6789*********************9886 PP

>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.9   0.0   2.5e-14   1.6e-11       2     203 ..      11     284 ..      10     308 .. 0.79

  Alignments for each domain:
  == domain 1  score: 43.9 bits;  conditional E-value: 2.5e-14
                 EEEEESSHHHHHHHHHHEEEEEEEEEE....TTEEEEEEEETTEEEEEEE--...SSHHHHH.HHHHHHHHHHC--SEEEEEEEEEES...STTT-TT- CS
   PNP_UDP_1   2 iaiivgspgevellaespleetpfgre...grgfkfvtGtlkgkpvvivstG...iGkpnaa.vvaeirllkefgvkaiiriGtaGgl...npdlkvGD 90 
                 ia i++ p ev++  +  l++++   +        + +G+l+g+ vviv+      G++ aa vv  +r+    +    +++G+ Gg+   n+d+++GD
  EEA18689.1  11 IAWICALPVEVAAAGAM-LDKIHSPLPkpsTDPNAYELGELNGHYVVIVCLPygvYGTVAAAnVVSHMRATY-PRLQYGLMVGIGGGVpgkNHDIRLGD 107
                 77788888888888887.4444333333455667999*************999977******5555555555.456777999999************** PP

                 EEEEEE......EEESSSCCGCCTHHCC.......................................TCCCCTTSSEE--HHHHHHHHH.......... CS
   PNP_UDP_1  91 vvipdd......ainfdgrsplygpkee.......................................gqyfpdsydapadpelrallke.......... 134
                 vv+++       +i++d++ +  g k e                                       +  +  + ++ + ++l++ll+e          
  EEA18689.1 108 VVVSKPaeeysgVIQYDYGKAVQGGKLErtgtlnkpphsllsymnqleakrmmgskndvskiveevlERNPGLKERFSPPEQLTDLLFEssyhhttgeg 206
                 *****95555555999999998888888***************************************999999999999**********9888766666 PP

                 ..CHHTTT................TTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTB CS
   PNP_UDP_1 135 ..aaealg................ikvhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArelgipfaairvvsdlaag 203
                   +    +                + +h+G++a++d++  ++e ++rl ++ g+ + eME+a +       ++p ++ir++ d+ + 
  EEA18689.1 207 tcE----NcdkeqlvkrkpretrtPYIHYGLIASGDQVIKDSETRDRLAQQHGILCFEMEAAGIMD-----ELPTLVIRGICDYCDS 284
                 551....14455666777788888************************************998754.....6888888888885555 PP

>> TPR_MalT  MalT-like TPR region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.3       2.4   1.5e+03     232     276 ..     537     578 ..     497     608 .. 0.61
   2 !   16.2   0.7   7.9e-06    0.0051      86     183 ..     728     828 ..     710     839 .. 0.90
   3 !   23.5   3.5   4.9e-08   3.1e-05      40     193 ..     890    1048 ..     880    1080 .. 0.80

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 2.4
    TPR_MalT 232 sdddnhflelelrnlarvllalgrydeAlellerLlkaaeelgrv 276
                 ++++ ++le  l + +++ l++ ++++A ell    ++ ++lgr+
  EEA18689.1 537 TQASAYILENGLDLSMYLALLQEHEQDAVELLS---EDFTDLGRY 578
                 444567777777888888888888888888764...344444444 PP

  == domain 2  score: 16.2 bits;  conditional E-value: 7.9e-06
    TPR_MalT  86 qaeilvaqGrLheAletyeqalqlateqglqqlplvgfllvlladllyEwndLeeAeqhlqeGielleql...epeaaldayvllarialaqGdleeAe 181
                 +a  l+ +Gr +eA+  y++ ++  +e+ ++q +     +++la  ++ +++  eAe+   + +e ++ +   +   +l + + la  ++ qG++ e+e
  EEA18689.1 728 IATCLFSDGRYQEAEVFYRKLMTINQEKAGPQDRSTLTSMASLASTYRHQGRWNEAEELEVQVMETSRAVlgaDHSDTLNSMANLASTYWNQGRWNESE 826
                 5678999***************************999999*****************************87434467899******************9 PP

    TPR_MalT 182 tl 183
                 +l
  EEA18689.1 827 KL 828
                 97 PP

  == domain 3  score: 23.5 bits;  conditional E-value: 4.9e-08
    TPR_MalT   40 iaatavlGeasllqGdleaAlqalq...eaeklarqadslhvallallqqaeilvaqGrLheAletyeqalqlateqglqqlplvgfllvlladlly 133 
                  + ++a+l+ ++l qG+ ++A++      e+ k+ ++ ++++ +l+ +  +a  ++ qGr  eA+++  q ++  ++  +++ p      + la  ++
  EEA18689.1  890 LNTMANLASTYLSQGRWTEAEKLDIqvmETFKTVLGVEHPD-TLTIMANLASAYRSQGRYNEAEKLEGQVMETRKTVLGAEHPDTLASIANLASTYW 985 
                  567889999***********997441114444455666665.99999999*********************************9999999******* PP

    TPR_MalT  134 EwndLeeAeqhlqeGielleql...epeaaldayvllarialaqGdleeAetllekaeelare 193 
                   +++L eAe+   + +e+++     +   +l + + la    +qG+l++A++l+++   l ++
  EEA18689.1  986 NQGRLSEAEKLEIQVMEISKAAlgvDHPNTLTSMANLACTWKSQGKLQNALALIKQCADLRNR 1048
                  *******************9965434467889999********************99888765 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.5   0.0   7.6e-11   4.8e-08      11     183 ..     350     522 ..     340     542 .. 0.73
   2 ?   -2.6   0.1       3.9   2.5e+03     194     224 ..     841     871 ..     811     889 .. 0.66

  Alignments for each domain:
  == domain 1  score: 32.5 bits;  conditional E-value: 7.6e-11
                 HHHCTTTSCSEEEEEEESTTSSHHHHHHHHCCSHCCCCCCBTEEEEEEEESXXHHHHHHHXXHHHHHCCCTTSSSS-STTSHHHHHHHHCCCT...TEE CS
      NB-ARC  11 kLlekdelqslvvalvGmgGvGKttlakqilnksdevegrFdsvawvvvsktdkseeiletilkeLslseddleekeeveslkrklvrlLltk...rfl 106
                     + +++   +a+ G gGvGKt +a +  +     + +  s+ w+  + + ++e+ + +i+++L+ +     + +  e  k+++  +L +    + l
  EEA18689.1 350 LITMQYGPK--RIAITGLGGVGKTQVALELAHRIRDQD-EKCSIFWIPCTSHAMIEQSFLRIAQKLGIH-----NVNPAE-VKEQVKIYLSSErsgKWL 439
                 444455566..89****************999944433.444899*********************877.....333333.44566666655534799* PP

                 EEEEEE-SHHHH........HHHH...CHTTSEEEEEESBCCCCCCS-S-EEEEEESS--HHHHHHHHHHCCTS-GGCHH...C CS
      NB-ARC 107 lvlDDVweeedw...dkigvvlpa...renrlrvllTTRdeevanavsatsekievelLekdeawellenkvfekkleekes.l 183
                 lv+D   + e w     +  +l +   ++++ r+l+T+R++++a + +   +++ +    k+ a ++le+   +k+l  +++  
  EEA18689.1 440 LVFDNADDVEMWfapSDTAPPLEDfipESEQGRILFTSRNRKLAMKLAP-FHVVPIPDVDKETAVKILEKTLARKELLRDTTtT 522
                 ****9999999833334555555522268999***********777666.6666677789999999999999999988776542 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 3.9
                 CTT-HHHHHHHHHHHC-TCSCCHHHHHHHHH CS
      NB-ARC 194 ckGlPlalkvlggllstkktveewkkvlekl 224
                     Pl+l ++++l  t +   +w++++e +
  EEA18689.1 841 GTEHPLTLTSMASLALTYQNQGRWNEAEELF 871
                 3336999999999999889999999988754 PP

>> TPR_4  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.0      0.21   1.4e+02       5      23 ..     768     786 ..     765     786 .. 0.88
   2 ?    1.7   0.0      0.86   5.5e+02       4      17 ..     809     822 ..     807     826 .. 0.88
   3 ?    5.6   0.0     0.047        30       5      24 ..     852     871 ..     849     873 .. 0.89
   4 ?    3.8   0.0      0.18   1.1e+02       4      21 ..     893     910 ..     891     912 .. 0.91
   5 ?    1.7   0.0      0.84   5.4e+02       5      21 ..     936     952 ..     933     954 .. 0.90
   6 ?    4.6   0.0       0.1        66       6      21 ..     979     994 ..     978     996 .. 0.92

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.21
       TPR_4   5 laLArallalGdldeAral 23 
                 + LA ++ ++G++ eA++l
  EEA18689.1 768 ASLASTYRHQGRWNEAEEL 786
                 67999***********986 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.86
       TPR_4   4 llaLArallalGdl 17 
                  ++LA +++ +G++
  EEA18689.1 809 MANLASTYWNQGRW 822
                 589*********97 PP

  == domain 3  score: 5.6 bits;  conditional E-value: 0.047
       TPR_4   5 laLArallalGdldeArall 24 
                 + LA +++ +G++ eA++l+
  EEA18689.1 852 ASLALTYQNQGRWNEAEELF 871
                 679**************986 PP

  == domain 4  score: 3.8 bits;  conditional E-value: 0.18
       TPR_4   4 llaLArallalGdldeAr 21 
                  ++LA ++l +G++ eA+
  EEA18689.1 893 MANLASTYLSQGRWTEAE 910
                 689**************7 PP

  == domain 5  score: 1.7 bits;  conditional E-value: 0.84
       TPR_4   5 laLArallalGdldeAr 21 
                 ++LA a+  +G++ eA+
  EEA18689.1 936 ANLASAYRSQGRYNEAE 952
                 79***********9997 PP

  == domain 6  score: 4.6 bits;  conditional E-value: 0.1
       TPR_4   6 aLArallalGdldeAr 21 
                 +LA +++ +G+l eA+
  EEA18689.1 979 NLASTYWNQGRLSEAE 994
                 89***********997 PP

>> TPR_3  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.0     0.027        17      12      31 ..     733     750 ..     729     755 .. 0.79
   2 ?   -2.2   0.0       6.8   4.4e+03       6      23 ..     769     786 ..     769     786 .. 0.85
   3 !   11.4   0.0   0.00038      0.24       6      24 ..     853     871 ..     852     873 .. 0.94
   4 ?   -1.9   0.0       5.5   3.5e+03       7      23 ..     896     912 ..     895     913 .. 0.88
   5 ?    1.5   0.0      0.49   3.1e+02       7      23 ..     938     954 ..     937     954 .. 0.85
   6 ?    3.7   0.0       0.1        64       7      23 ..     980     996 ..     974     996 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.027
                 HHTT-HHHHHHH..HHHHHH CS
       TPR_3  12 ynkkkyqeArelfsYallai 31 
                 ++ ++yqeA+ +  Y+ l +
  EEA18689.1 733 FSDGRYQEAEVF--YRKLMT 750
                 6789********..886655 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 6.8
                 HHHHHHHHTT-HHHHHHH CS
       TPR_3   6 syAaefynkkkyqeArel 23 
                 s+A ++  +++ +eA+el
  EEA18689.1 769 SLASTYRHQGRWNEAEEL 786
                 678888889999999998 PP

  == domain 3  score: 11.4 bits;  conditional E-value: 0.00038
                 HHHHHHHHTT-HHHHHHH. CS
       TPR_3   6 syAaefynkkkyqeArelf 24 
                 s+A +++n+++ +eA+elf
  EEA18689.1 853 SLALTYQNQGRWNEAEELF 871
                 79****************5 PP

  == domain 4  score: -1.9 bits;  conditional E-value: 5.5
                 HHHHHHHTT-HHHHHHH CS
       TPR_3   7 yAaefynkkkyqeArel 23 
                 +A ++ ++++ +eA+ l
  EEA18689.1 896 LASTYLSQGRWTEAEKL 912
                 7999999*******987 PP

  == domain 5  score: 1.5 bits;  conditional E-value: 0.49
                 HHHHHHHTT-HHHHHHH CS
       TPR_3   7 yAaefynkkkyqeArel 23 
                 +A ++ ++++y+eA+ l
  EEA18689.1 938 LASAYRSQGRYNEAEKL 954
                 6778889*******976 PP

  == domain 6  score: 3.7 bits;  conditional E-value: 0.1
                 HHHHHHHTT-HHHHHHH CS
       TPR_3   7 yAaefynkkkyqeArel 23 
                 +A ++ n+++++eA+ l
  EEA18689.1 980 LASTYWNQGRLSEAEKL 996
                 8*************976 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0      0.69   4.4e+02      11      33 ..     720     742 ..     713     742 .. 0.85
   2 ?    4.2   0.0       0.1        67      15      34 .]     766     785 ..     764     785 .. 0.91
   3 ?    0.5   0.1       1.6   1.1e+03      14      32 ..     807     825 ..     800     827 .. 0.65
   4 ?    4.8   0.1     0.068        43      15      34 .]     850     869 ..     848     869 .. 0.91
   5 ?    6.3   0.1     0.022        14      15      34 .]     892     911 ..     890     911 .. 0.90
   6 ?    7.1   0.0     0.013       8.2      15      34 .]     934     953 ..     928     953 .. 0.90
   7 ?   -0.5   0.0       3.3   2.1e+03      17      34 .]     978     995 ..     971     995 .. 0.86
   8 ?    6.3   0.0     0.022        14      14      33 ..    1017    1036 ..    1009    1037 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.69
      TPR_17  11 nnadaynnLAelllknGdlmtAr 33 
                 n+ d+  n A++l + G++++A+
  EEA18689.1 720 NYLDLIENIATCLFSDGRYQEAE 742
                 556677799************96 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.1
      TPR_17  15 aynnLAelllknGdlmtArq 34 
                 ++  LA +++++G++ +A++
  EEA18689.1 766 SMASLASTYRHQGRWNEAEE 785
                 6889*************986 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 1.6
      TPR_17  14 daynnLAelllknGdlmtA 32 
                 +++ nLA ++ ++G++ + 
  EEA18689.1 807 NSMANLASTYWNQGRWNES 825
                 4566666666699887665 PP

  == domain 4  score: 4.8 bits;  conditional E-value: 0.068
      TPR_17  15 aynnLAelllknGdlmtArq 34 
                 ++  LA ++ ++G++ +A++
  EEA18689.1 850 SMASLALTYQNQGRWNEAEE 869
                 6889*************986 PP

  == domain 5  score: 6.3 bits;  conditional E-value: 0.022
      TPR_17  15 aynnLAelllknGdlmtArq 34 
                  + nLA ++l++G++ +A++
  EEA18689.1 892 TMANLASTYLSQGRWTEAEK 911
                 689*************9985 PP

  == domain 6  score: 7.1 bits;  conditional E-value: 0.013
      TPR_17  15 aynnLAelllknGdlmtArq 34 
                  + nLA +++++G++ +A++
  EEA18689.1 934 IMANLASAYRSQGRYNEAEK 953
                 689***************85 PP

  == domain 7  score: -0.5 bits;  conditional E-value: 3.3
      TPR_17  17 nnLAelllknGdlmtArq 34 
                  nLA ++ ++G+l +A++
  EEA18689.1 978 ANLASTYWNQGRLSEAEK 995
                 69999999****999985 PP

  == domain 8  score: 6.3 bits;  conditional E-value: 0.022
      TPR_17   14 daynnLAelllknGdlmtAr 33  
                   ++ nLA +++++G+l+ A+
  EEA18689.1 1017 TSMANLACTWKSQGKLQNAL 1036
                  6899************9996 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0      0.14        92      41      60 ..     729     748 ..     726     761 .. 0.84
   2 ?    0.9   0.0       1.2   7.6e+02      34      56 ..     764     786 ..     754     790 .. 0.75
   3 ?    0.0   0.0       2.2   1.4e+03       2      18 ..     811     827 ..     798     828 .. 0.78
   4 ?    4.6   0.0     0.084        54       3      21 ..     854     872 ..     852     876 .. 0.88
   5 !    7.6   0.0    0.0096       6.2       3      55 ..     896     953 ..     894     958 .. 0.72
   6 ?    3.5   0.0      0.18   1.1e+02      30      55 ..     970     995 ..     965    1001 .. 0.68

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.14
      TPR_16  41 gdaalrqgrlaeAaalyraa 60 
                 + +++  gr++eA+ +yr++
  EEA18689.1 729 ATCLFSDGRYQEAEVFYRKL 748
                 789***********999985 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 1.2
      TPR_16  34 aeAllllgdaalrqgrlaeAaal 56 
                   ++  l+  + +qgr+ eA++l
  EEA18689.1 764 LTSMASLASTYRHQGRWNEAEEL 786
                 56667789999999999999865 PP

  == domain 3  score: 0.0 bits;  conditional E-value: 2.2
      TPR_16   2 alaraalragdyddAaa 18 
                 +la  ++++g++ + ++
  EEA18689.1 811 NLASTYWNQGRWNESEK 827
                 57778888888887766 PP

  == domain 4  score: 4.6 bits;  conditional E-value: 0.084
      TPR_16   3 laraalragdyddAaaale 21 
                 la+ + ++g++ +A++++ 
  EEA18689.1 854 LALTYQNQGRWNEAEELFV 872
                 8999************995 PP

  == domain 5  score: 7.6 bits;  conditional E-value: 0.0096
      TPR_16   3 laraalragdyddAaaa.......leaalkrdpssPdaaeAllllgdaalrqgrlaeAaa 55 
                 la  +l +g++++A+++       ++++l     +Pd+   + +l+ a+  qgr+ eA+ 
  EEA18689.1 896 LASTYLSQGRWTEAEKLdiqvmetFKTVLGVE--HPDTLTIMANLASAYRSQGRYNEAEK 953
                 67777777777777765444444466666666..89999999999999999999988884 PP

  == domain 6  score: 3.5 bits;  conditional E-value: 0.18
      TPR_16  30 sPdaaeAllllgdaalrqgrlaeAaa 55 
                 +Pd+ ++  +l+  ++ qgrl eA+ 
  EEA18689.1 970 HPDTLASIANLASTYWNQGRLSEAEK 995
                 56666666667777777777777763 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.0   5.9e-08   3.8e-05       1      86 [.     336     405 ..     336     476 .. 0.72

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 5.9e-08
      AAA_16   1 rlvGReeeleqLlsalervrsgrpelvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipysalaqalareellrqll 86 
                 ++vGR +e+ +L++++    + +p  + ++G  GvGK+ ++ el+++++++      +kc  +        ++ +   +  ++q  
  EEA18689.1 336 NFVGRHDEITKLEELIT--MQYGPKRIAITGLGGVGKTQVALELAHRIRDQ-----DEKCSIF--------WIPCT-SHAMIEQSF 405
                 59**************7..6678999***********************99.....4444444........33333.223333333 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.0   5.1e-08   3.3e-05       2     164 ..     359     511 ..     358     513 .. 0.83

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 5.1e-08
                 CEEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-....-HCHHHCCCCTS--SSS-CCHHHH.CCSCCCEEEEEE-STT-SS-TC CS
       NACHT   2 lvilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgna.rsladllfsqlpepaapvsevwavl.lelperlLlilDglDelvtdlg 98 
                  ++++G  G+GKT  + +la+ +++++ +    + +F++++ +   ++++ +++a+ l  +   pa+  ++v ++l  e+  + Ll++D +D+++  + 
  EEA18689.1 359 RIAITGLGGVGKTQVALELAHRIRDQDEK----CSIFWIPCTSHAMIEQSfLRIAQKLGIHNVNPAEVKEQVKIYLsSERSGKWLLVFDNADDVEMWFA 453
                 5899*********9999999999988833....579********999999988888887777777777777555551688999************9888 PP

                 H.........HHHHHCTTTTT--EEEEEEECCCHHHHCTTSSCE..EEEE--TCCHHHHHHHHCTT CS
       NACHT  99 qkekqpvrtlLselirkkllpeasllltvrpralrdleeqleeaivlevegfsesrrkqlvrkyfs 164
                 +     +   L++ i++    + ++l t+r+r+l   + +l+  +v+ +++  ++ ++++++k+++
  EEA18689.1 454 P---SDTAPPLEDFIPE--SEQGRILFTSRNRKL---AMKLAPFHVVPIPDVDKETAVKILEKTLA 511
                 8...6666679999***..99999******9998...88888888899999998888888888775 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0       9.7   6.2e+03      11      27 ..     732     748 ..     728     770 .. 0.65
   2 ?    1.8   0.0      0.89   5.7e+02       6      23 ..     769     786 ..     764     786 .. 0.90
   3 ?    0.3   0.0       2.6   1.7e+03       7      22 ..     812     827 ..     809     828 .. 0.88
   4 ?    1.0   0.0       1.6   1.1e+03       7      24 ..     854     871 ..     851     879 .. 0.89
   5 ?    2.8   0.0      0.43   2.8e+02       7      23 ..     896     912 ..     891     922 .. 0.90
   6 ?    2.4   0.1      0.57   3.7e+02       7      23 ..     938     954 ..     935     954 .. 0.92
   7 ?    4.6   0.0      0.12        74       7      23 ..     980     996 ..     975     996 .. 0.91

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 9.7
      TPR_14  11 llalGdpdeAiallrra 27 
                 l+  G+++eA+  +r++
  EEA18689.1 732 LFSDGRYQEAEVFYRKL 748
                 67889999999999986 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.89
      TPR_14   6 alaeallalGdpdeAial 23 
                  la+ ++++G++ eA++l
  EEA18689.1 769 SLASTYRHQGRWNEAEEL 786
                 599************985 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 2.6
      TPR_14   7 laeallalGdpdeAia 22 
                 la+ ++++G++ e+++
  EEA18689.1 812 LASTYWNQGRWNESEK 827
                 89********999887 PP

  == domain 4  score: 1.0 bits;  conditional E-value: 1.6
      TPR_14   7 laeallalGdpdeAiall 24 
                 la  + ++G++ eA++l+
  EEA18689.1 854 LALTYQNQGRWNEAEELF 871
                 89999***********98 PP

  == domain 5  score: 2.8 bits;  conditional E-value: 0.43
      TPR_14   7 laeallalGdpdeAial 23 
                 la+ +l +G++ eA++l
  EEA18689.1 896 LASTYLSQGRWTEAEKL 912
                 89************997 PP

  == domain 6  score: 2.4 bits;  conditional E-value: 0.57
      TPR_14   7 laeallalGdpdeAial 23 
                 la+a++ +G++ eA++l
  EEA18689.1 938 LASAYRSQGRYNEAEKL 954
                 89************986 PP

  == domain 7  score: 4.6 bits;  conditional E-value: 0.12
      TPR_14   7 laeallalGdpdeAial 23 
                 la+ ++++G++ eA++l
  EEA18689.1 980 LASTYWNQGRLSEAEKL 996
                 89************986 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.5   0.0    0.0072       4.6       3      45 ..     736     786 ..     734     796 .. 0.78
   2 ?    6.0   0.0     0.021        14      28      76 ..     853     910 ..     842     912 .. 0.64
   3 ?    3.8   0.0       0.1        67      29      77 ..     896     953 ..     878     957 .. 0.61
   4 ?    2.0   0.0      0.37   2.4e+02      29      45 ..     938     954 ..     926     995 .. 0.76
   5 ?    0.7   0.0         1   6.4e+02       2      44 ..     945     995 ..     944    1042 .. 0.71

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0072
                 T-HHHHHHHHHHHH.........HHH--HHHHHHHHHHHHHTT-HHHHHHH CS
      ANAPC3   3 nnyknAiflaerll........aaetespedayllAlclylngqykrAyel 45 
                 ++y++A+ ++ +l+         +++  + +   lA ++ ++g++++A el
  EEA18689.1 736 GRYQEAEVFYRKLMtinqekagPQDRSTLTSMASLASTYRHQGRWNEAEEL 786
                 68************887763322445555555568*************875 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.021
                 HHHHHHHHTT-HHHHHHHHHCT.SHHHC-H.....HHHHHHH...HHHHHTT-HHHHH CS
      ANAPC3  28 llAlclylngqykrAyellrka.klnsksl.....gcrylfA...qcllkLkkyeeAi 76 
                  lAl++ ++g++++A el+ +  +++ + l       + ++A    ++l ++++ eA+
  EEA18689.1 853 SLALTYQNQGRWNEAEELFVQVmEIRMTMLgaehlDTLNTMAnlaSTYLSQGRWTEAE 910
                 5899999999999999999888666655553333333333333325556666666665 PP

  == domain 3  score: 3.8 bits;  conditional E-value: 0.1
                 HHHHHHHTT-HHHH.......HHHHHCTSHHHC-HHHHHHHH..HHHH.HTT-HHHHHH CS
      ANAPC3  29 lAlclylngqykrA.......yellrkaklnskslgcrylfA..qcll.kLkkyeeAia 77 
                 lA +++++g++++A       +e +++  l  +++  + ++A   +++  +++y+eA++
  EEA18689.1 896 LASTYLSQGRWTEAekldiqvMETFKTV-LGVEHPDTLTIMAnlASAYrSQGRYNEAEK 953
                 6778888888888733332212233333.566666777777755444545577777765 PP

  == domain 4  score: 2.0 bits;  conditional E-value: 0.37
                 HHHHHHHTT-HHHHHHH CS
      ANAPC3  29 lAlclylngqykrAyel 45 
                 lA ++ ++g+y++A +l
  EEA18689.1 938 LASAYRSQGRYNEAEKL 954
                 67788888888888765 PP

  == domain 5  score: 0.7 bits;  conditional E-value: 1
                 TT-HHHHHHHHHHHH.........HHH--HHHHHHHHHHHHHTT-HHHHHH CS
      ANAPC3   2 qnnyknAiflaerll........aaetespedayllAlclylngqykrAye 44 
                 q++y++A+ l   ++        a +++ + ++  lA ++ ++g+  +A +
  EEA18689.1 945 QGRYNEAEKLEGQVMetrktvlgAEHPDTLASIANLASTYWNQGRLSEAEK 995
                 778888888888888777666655667777777778888888888888755 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   1.6e-05     0.011       1      60 [.     337     398 ..     337     437 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 1.6e-05
    ATPase_2   1 FfdRekelkeleeilerepn.eiyfiYGpegsGKtaLlkeiienledkdk.yviyyialree 60 
                 F+ R  e+ +lee++ ++   + + i+G  g+GKt++  e++ + +d+d+   i+ i+  ++
  EEA18689.1 337 FVGRHDEITKLEELITMQYGpKRIAITGLGGVGKTQVALELAHRIRDQDEkCSIFWIPCTSH 398
                 899**********998865415578*******************976655378888887655 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   2.7e-05     0.017       8     103 ..     360     448 ..     353     465 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 2.7e-05
      AAA_22   8 lvvtGesGtGKTtllrrlleqldeeakaee.erpevvfvtlpsstsskdllrellralglelkaerlsseellealeqalrarav.ielliiDEaqhl 103
                 +++tG  G+GKT ++ +l+++       ++ e+ +++ + ++s    ++ + +++++lg  +     +  e+ e++  +l++ +  + ll+ D+a+ +
  EEA18689.1 360 IAITGLGGVGKTQVALELAHRIR-----DQdEKCSIFWIPCTSHAMIEQSFLRIAQKLGIHNV----NPAEVKEQVKIYLSSERSgKWLLVFDNADDV 448
                 89******************983.....224699999********999999********7444....6999********99999999*********87 PP

>> DUF4074  Domain of unknown function (DUF4074)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0       2.6   1.7e+03      33      62 ..     755     786 ..     747     787 .. 0.71
   2 ?   -1.5   0.0       4.9   3.2e+03      42      62 ..     808     828 ..     801     829 .. 0.85
   3 ?    4.3   0.0      0.08        51      41      62 ..     891     912 ..     884     913 .. 0.90
   4 ?    3.9   0.0      0.11        67      44      62 ..     936     954 ..     927     955 .. 0.87
   5 ?    0.5   0.0       1.2   7.7e+02      42      62 ..     976     996 ..     964     997 .. 0.85
   6 ?   -2.4   0.0       9.7   6.2e+03      44      59 ..    1020    1035 ..    1010    1038 .. 0.76

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 2.6
     DUF4074  33 hhGpCdphp..tYtdLsahhtsqGriqeapkL 62 
                 + Gp d     + + L++ +  qGr  ea  L
  EEA18689.1 755 KAGPQDRSTltSMASLASTYRHQGRWNEAEEL 786
                 4466665333367789999999******9876 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 4.9
     DUF4074  42 tYtdLsahhtsqGriqeapkL 62 
                 + ++L++ +  qGr  e+ kL
  EEA18689.1 808 SMANLASTYWNQGRWNESEKL 828
                 6688999999*******9998 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.08
     DUF4074  41 ptYtdLsahhtsqGriqeapkL 62 
                  t ++L++ + sqGr  ea kL
  EEA18689.1 891 NTMANLASTYLSQGRWTEAEKL 912
                 6899***************998 PP

  == domain 4  score: 3.9 bits;  conditional E-value: 0.11
     DUF4074  44 tdLsahhtsqGriqeapkL 62 
                 ++L++++ sqGr  ea kL
  EEA18689.1 936 ANLASAYRSQGRYNEAEKL 954
                 68999***********998 PP

  == domain 5  score: 0.5 bits;  conditional E-value: 1.2
     DUF4074  42 tYtdLsahhtsqGriqeapkL 62 
                 + ++L++ +  qGr  ea kL
  EEA18689.1 976 SIANLASTYWNQGRLSEAEKL 996
                 5578999999********998 PP

  == domain 6  score: -2.4 bits;  conditional E-value: 9.7
     DUF4074   44 tdLsahhtsqGriqea 59  
                  ++L+    sqG+ q+a
  EEA18689.1 1020 ANLACTWKSQGKLQNA 1035
                  56778889******98 PP

>> SRP54  SRP54-type protein, GTPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   5.4e-05     0.035       2      70 ..     358     427 ..     357     437 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 5.4e-05
                 EEEEEEESTTSSHHHHHHHHHHHHHHTTS-EEEEEESTSSTTHHHH.HHHHHHHTTEEEEESSTTSCHHH CS
       SRP54   2 nvillvGlqGaGKTttlaKLaallkkegkkvllvaaDtfRaaAveQ.Lktlaeklgvpvikkkeeadpaa 70 
                 + i++ Gl G+GKT+ +  La++++++ +k+ +    +   a +eQ    +a+klg++ ++  e +++++
  EEA18689.1 358 KRIAITGLGGVGKTQVALELAHRIRDQDEKCSIFWIPCTSHAMIEQsFLRIAQKLGIHNVNPAEVKEQVK 427
                 67899****************************9999999999999656678888888777665555555 PP

>> ParA  NUBPL iron-transfer P-loop NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00033      0.21       9      38 ..     362     391 ..     358     428 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00033
        ParA   9 lSgKGGVGKStvavnlAlaLakkglkvgll 38 
                 + g GGVGK+ va +lA  +++++ k +++
  EEA18689.1 362 ITGLGGVGKTQVALELAHRIRDQDEKCSIF 391
                 5699*******************9998886 PP

>> KdpD  Osmosensitive K+ channel His kinase sensor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.0    0.0089       5.7       6      51 ..     359     404 ..     354     427 .. 0.82
   2 ?    1.9   0.0       0.2   1.3e+02      99     135 ..     858     895 ..     823     905 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0089
        KdpD   6 kiflGaapGvGktyamLeeaqelkeegvdvviglvethgrketeal 51 
                 +i +    GvGkt   Le a++ +++  ++ i ++   +++ +e+ 
  EEA18689.1 359 RIAITGLGGVGKTQVALELAHRIRDQDEKCSIFWIPCTSHAMIEQS 404
                 67777788***********************999988777776665 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.2
        KdpD  99 srhekryqdveelLeagidV.ittvnvqhleslndvve 135
                  +++ r+++ eel  + +++ +t +  +hl+ ln + +
  EEA18689.1 858 YQNQGRWNEAEELFVQVMEIrMTMLGAEHLDTLNTMAN 895
                 57899**************9456679*******98865 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00058      0.37       1      21 [.     360     380 ..     360     412 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00058
      AAA_18   1 IlltGtpGvGKttlakeLskr 21 
                 I++tG  GvGKt++a eL+ r
  EEA18689.1 360 IAITGLGGVGKTQVALELAHR 380
                 89****************877 PP

>> RPN6_N  26S proteasome regulatory subunit RPN6 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   0.0    0.0056       3.6       6      58 ..     734     787 ..     729     802 .. 0.78
   2 ?    0.1   0.1       1.6     1e+03       6      59 ..     860     914 ..     849     923 .. 0.75
   3 ?    1.3   0.2      0.67   4.3e+02       3      57 ..     941     996 ..     939    1008 .. 0.84

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0056
      RPN6_N   6 ks.dpkeaeelykeilskkskedeealreqeqalleLgelyrdqkkaeeLaeli 58 
                 ++ +++eae  y+++++ ++++   + r+  +++ +L++ yr+q++ +e  el 
  EEA18689.1 734 SDgRYQEAEVFYRKLMTINQEKAGPQDRSTLTSMASLASTYRHQGRWNEAEELE 787
                 44589***************9999999*****************8877665542 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 1.6
      RPN6_N   6 ks.dpkeaeelykeilskkskedeealreqeqalleLgelyrdqkkaeeLaelik 59 
                 ++ + +eaeel+ ++++ +++   ++  +  + + +L++ y +q++ +e  +l  
  EEA18689.1 860 NQgRWNEAEELFVQVMEIRMTMLGAEHLDTLNTMANLASTYLSQGRWTEAEKLDI 914
                 4446788999999999988888778888888889999999988888777777654 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.67
      RPN6_N   3 elaks.dpkeaeelykeilskkskedeealreqeqalleLgelyrdqkkaeeLael 57 
                 ++ ++ +++eae+l  ++++++++   ++  +  +++ +L++ y +q++ +e  +l
  EEA18689.1 941 AYRSQgRYNEAEKLEGQVMETRKTVLGAEHPDTLASIANLASTYWNQGRLSEAEKL 996
                 555666999*************999999999***************9998887766 PP

>> DUF1897  Domain of unknown function (DUF1897)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.1       2.9   1.8e+03       8      15 ..       7      14 ..       5      14 .. 0.88
   2 ?    4.6   0.1     0.034        22      18      34 ..     774     790 ..     772     792 .. 0.93
   3 ?   -2.6   0.0       6.1   3.9e+03      18      30 ..     900     912 ..     900     916 .. 0.82
   4 ?    6.4   0.4    0.0099       6.3      18      34 ..     942     958 ..     940     960 .. 0.94
   5 ?   -1.1   0.0       2.2   1.4e+03      18      34 ..     984    1000 ..     984    1002 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 2.9
     DUF1897  8 aDYSAqWa 15
                +DY+ +W+
  EEA18689.1  7 SDYTIAWI 14
                7******8 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.034
     DUF1897  18 YrsiGmheeAeaieqqi 34 
                 Yr++G   eAe  e q+
  EEA18689.1 774 YRHQGRWNEAEELEVQV 790
                 ***********999997 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 6.1
     DUF1897  18 YrsiGmheeAeai 30 
                 Y s+G   eAe  
  EEA18689.1 900 YLSQGRWTEAEKL 912
                 889*******965 PP

  == domain 4  score: 6.4 bits;  conditional E-value: 0.0099
     DUF1897  18 YrsiGmheeAeaieqqi 34 
                 Yrs+G   eAe  e q+
  EEA18689.1 942 YRSQGRYNEAEKLEGQV 958
                 *************9997 PP

  == domain 5  score: -1.1 bits;  conditional E-value: 2.2
     DUF1897   18 YrsiGmheeAeaieqqi 34  
                  Y  +G   eAe  e q+
  EEA18689.1  984 YWNQGRLSEAEKLEIQV 1000
                  6789*******999886 PP

>> CutA1  CutA1 divalent ion tolerance protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.1      0.02        13      32      57 ..     767     792 ..     762     803 .. 0.80
   2 ?    1.8   0.1      0.33   2.1e+02      27      53 ..     804     830 ..     789     843 .. 0.76
   3 ?   -1.9   0.0       4.8   3.1e+03      35      53 ..     854     872 ..     840     881 .. 0.80
   4 ?   -1.4   0.0       3.3   2.1e+03      24      48 ..     885     909 ..     856     924 .. 0.63
   5 ?   -1.7   0.0       4.1   2.6e+03      30      49 ..     933     952 ..     931     970 .. 0.78
   6 ?    0.1   0.1       1.1   7.4e+02      32      51 ..     977     998 ..     950    1007 .. 0.78

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.02
                 EEEEEEEEEETTEEEEEEEEEEEEEE CS
       CutA1  32 lpkieSvYrWkgkieedkEvlllikt 57 
                 + ++ S+Yr +g+++e++E  + +  
  EEA18689.1 767 MASLASTYRHQGRWNEAEELEVQVME 792
                 45689**************9886544 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.33
                 SEEEEEEEEEEEEEETTEEEEEEEEEE CS
       CutA1  27 ACvnilpkieSvYrWkgkieedkEvll 53 
                    n + ++ S+Y+ +g+++e++   +
  EEA18689.1 804 DTLNSMANLASTYWNQGRWNESEKLDM 830
                 566788889***********9986655 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 4.8
                 EEEEEEETTEEEEEEEEEE CS
       CutA1  35 ieSvYrWkgkieedkEvll 53 
                 +  +Y+ +g+++e++E  +
  EEA18689.1 854 LALTYQNQGRWNEAEELFV 872
                 4557999*******99876 PP

  == domain 4  score: -1.4 bits;  conditional E-value: 3.3
                 TS-SEEEEEEEEEEEEEETTEEEEE CS
       CutA1  24 klaACvnilpkieSvYrWkgkieed 48 
                 +     n++ ++ S+Y  +g++ e+
  EEA18689.1 885 EHLDTLNTMANLASTYLSQGRWTEA 909
                 3344456666677777777776665 PP

  == domain 5  score: -1.7 bits;  conditional E-value: 4.1
                 EEEEEEEEEEEETTEEEEEE CS
       CutA1  30 nilpkieSvYrWkgkieedk 49 
                 +i+ ++ S Yr +g+ +e++
  EEA18689.1 933 TIMANLASAYRSQGRYNEAE 952
                 5778899*******999876 PP

  == domain 6  score: 0.1 bits;  conditional E-value: 1.1
                 EEEEEEEEEETTEEEEEE..EE CS
       CutA1  32 lpkieSvYrWkgkieedk..Ev 51 
                 + ++ S+Y+ +g++ e++  E+
  EEA18689.1 977 IANLASTYWNQGRLSEAEklEI 998
                 34589*******9998763344 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1081 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       736  (0.0410508); expected 358.6 (0.02)
Passed bias filter:                      605  (0.0337442); expected 358.6 (0.02)
Passed Vit filter:                        85  (0.00474092); expected 17.9 (0.001)
Passed Fwd filter:                        30  (0.00167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              28  [number of targets reported over threshold]
# CPU time: 1.06u 0.39s 00:00:01.45 Elapsed: 00:00:00.65
# Mc/sec: 5037.70
//
Query:       EEA18690.1  [L=312]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.4e-09   37.1   0.0      4e-09   36.4   0.0    1.3  1  Pollen_allerg_1  Pollen allergen
     0.0029   17.8   0.1      0.008   16.4   0.1    1.8  1  DPBB_1           Lytic transglycolase


Domain annotation for each model (and alignments):
>> Pollen_allerg_1  Pollen allergen
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.4   0.0   4.5e-13     4e-09      10      79 ..     204     287 ..     200     288 .. 0.93

  Alignments for each domain:
  == domain 1  score: 36.4 bits;  conditional E-value: 4.5e-13
  Pollen_allerg_1  10 n.p.ylavlvenvggagdisaVevkqggsseWtpmsrn...........wGavWqlnss..plkgplsfrvtssdgktlvadnVi 79 
                        p ++ ++++n gg g+i+  e++  g+s+W ++ ++           +Ga W+l+++  p + p+ +r+ts +g+++v++ Vi
       EEA18690.1 204 AgPyFFQITAVNAGGLGSIVGFEIRPDGQSNWLALVQEadypvghpqerYGA-WTLPANagPINLPMGVRLTSATGEQIVNEAVI 287
                      3355***********************************************9.*****559*********************998 PP

>> DPBB_1  Lytic transglycolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.1     9e-07     0.008      13      70 ..      88     170 ..      66     185 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 9e-07
                 -TTSSB--TTS-EEE-SSS-TT-EEEE..TT--EEEEEEEE----............................STTECEEE-HHHHHH CS
      DPBB_1  13 tacGecyevkcltaahktlplgtycrv..lsgksvtVtitDrgpf............................ppgrhiDLSkaAfek 70 
                  +cGec+e+      h+      y++   ++  +++  i+D +p                               + h+DLS  A+++
  EEA18690.1  88 LSCGECFELVR---THPN--GTLYASNdaGYSPPIILEIVDSCPCsantkwccgpgvdqcqevsnftygcplpDGSIHLDLSDVAMTR 170
                 69******999...4444..234666653338*************************************999777789****999976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (312 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       384  (0.0214178); expected 358.6 (0.02)
Passed bias filter:                      259  (0.0144459); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.35s 00:00:00.97 Elapsed: 00:00:00.56
# Mc/sec: 1669.34
//
Query:       EEA18691.1  [L=527]
Description: sugar transporter family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    3.1e-38  131.8  11.8      4e-38  131.4  11.8    1.1  1  Sugar_tr    Sugar (and other) transporter
    7.4e-30  104.1  20.1    7.4e-30  104.1  20.1    1.9  2  MFS_1       Major Facilitator Superfamily
    2.7e-06   27.0   0.4    4.8e-06   26.1   0.4    1.3  1  MFS_4       Uncharacterised MFS-type transporter YbfB
    7.6e-05   21.5   0.8    7.6e-05   21.5   0.8    2.0  2  ATG22       Vacuole effluxer Atg22 like
     0.0028   16.6   3.0      0.068   12.0   0.4    2.8  3  MFS_1_like  MFS_1 like family


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  131.4  11.8   1.1e-41     4e-38      44     415 ..      90     445 ..      47     473 .. 0.83

  Alignments for each domain:
  == domain 1  score: 131.4 bits;  conditional E-value: 1.1e-41
                 ...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHH CS
    Sugar_tr  44 ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvsl 142
                  ++ +++   ++l  + +G+l++g+l dr+GR++ +++  vl+++  + ++++    s+ ++i  R l Gi++G+  + +   + E  p++ Rg l ++
  EEA18691.1  90 PDSAVTWAITVTLMMRPVGALLFGTLCDRYGRRWPMIANLVLLIVLELASGFCS---SLHQFIGVRSLYGIAMGGLIGPCAAIALEDLPADARGLLSGV 185
                 455566777777778***************************************...9***************************************** PP

                 HHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHHTT-HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH..... CS
    Sugar_tr 143 yqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPrylvekgkeeeakevlaklrgeedadrelaeekdsleaeqeeekas 241
                 ++ ++++G l+a++++ +l  t++  gwr l ++ + p++l++i++++lPE+ ++l++k ++e+ ++  a+   e++ +++  e k+ +  +     +s
  EEA18691.1 186 FEGGTAIGNLIASTMYRALVPTTK-HGWRSLYWFGAGPPILIIIFRWWLPETDHFLMIKAEREARTRQKAD--AETESTENTSEFKTFIYDS----AKS 277
                 *******************77777.7**********************************77744444444..4555555666666666555....345 PP

                 HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THHHHHHHHHHHHHHHHHHHHH...HHHHHS-SHHHHHHHHHHHHHHHHHHH.. CS
    Sugar_tr 242 wkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsksllvtiivgvvnfvatfvai...flvdrfGRRtllllGaagmaicfvilgiv 337
                 +ke +        ll++++l+ + + + + a   y++ + +++ l+ +  + i+ ++ n  a+f +i   +++  +GRR   l+ ++g+++  +il  +
  EEA18691.1 278 VKENWLL------LLYMFLLMTGFNACVHGASDLYPTFLKNQVQLDAE-HMAIVSIMGNLGACFGGItlgYISGFLGRR---LTMICGCIVGSAIL--P 364
                 7777777......78888888888888889******************.99999999999999999988999*******...66666778888888..6 PP

                 HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH.........T CS
    Sugar_tr 338 alllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfpiiteaig.........g 415
                 a++l+ +   ++ +a vf+  f+ +    wgp+p +++  l+p  +R++   +++++ +la+  +++   i  e++           
  EEA18691.1 365 AYILTRG---MKLGACVFFQHFTTVGV--WGPIP-IHLVTLAPVTLRTLLVGLTYQLGNLASSPVTTAESIYGEKYPlapgadgmkR 445
                 9999999...8***********99997..99999.78899********************999888888887777776666655553 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.1  20.1   2.1e-33   7.4e-30       9     349 ..      70     420 ..      56     424 .. 0.84
   2 ?    0.4   0.1     0.067   2.4e+02      34      54 ..     451     471 ..     426     475 .. 0.78

  Alignments for each domain:
  == domain 1  score: 104.1 bits;  conditional E-value: 2.1e-33
       MFS_1   9 alarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgagalfpaga 107
                 a++++++ ++++  la ++ +  s++ +++t+      v++l++G l dr+Grr+ +++ l+l+++  l+  f+ssl  ++ +r l G+++g+l+  +a
  EEA18691.1  70 AFDYTTVPLTVT-ELAAQFDAPDSAVTWAITVTLMMRPVGALLFGTLCDRYGRRWPMIANLVLLIVLELASGFCSSLHQFIGVRSLYGIAMGGLIGPCA 167
                 677888888888.89****************************************************555557777669************99999999 PP

       MFS_1 108 aliadwfpkeergraigllsagfslGailgpllgglla..sslgWravfyilaivsllafvlfllllpeepperkrkspkeee.........kgtgpap 195
                 a++ +  p + rg+  g++ +g+++G +++     +l+  +  gWr+++++ a+  +l ++ f ++lpe+++    k+++e +         ++t    
  EEA18691.1 168 AIALEDLPADARGLLSGVFEGGTAIGNLIASTMYRALVptTKHGWRSLYWFGAGPPILIII-FRWWLPETDHFLMIKAEREARtrqkadaetEST---- 261
                 9999999999********************99999999778889**************866.9****9999999999999997777666544222.... PP

       MFS_1 196 lvp...awkallkdpvl.....w.illialllfffgfsg....lltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlllal 281
                   +    +k +  d        w +ll+++ll+ +gf++    ++ l p++l+ +  l+ +  +++++ ++ l+++++++ +g++s  lgrr +++ ++
  EEA18691.1 262 --EntsEFKTFIYDSAKsvkenWlLLLYMFLLM-TGFNAcvhgASDLYPTFLKNQVQLD-AEHMAIVSIMGNLGACFGGITLGYISGFLGRRLTMICGC 356
                 ..1333344444444333455574455555555.588888999****************.89***99************************99999999 PP

       MFS_1 282 lllllaalglallavtssavllllvlvliGf.glgfvfpsllalasdlappeeagtasglfntagslgg 349
                 +++++++ +++l+         l ++v++   +   v++++   ++ lap   +  ++gl+  +g+l++
  EEA18691.1 357 IVGSAILPAYILTRGM-----KLGACVFFQHfTTVGVWGPIPIHLVTLAPVTLRTLLVGLTYQLGNLAS 420
                 9999999999999999.....555555544447777889999999999999999999999998888876 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.067
       MFS_1  34 igllltlyalgaavaslplGr 54 
                 +  ++t+ a++++v+ l+lG+
  EEA18691.1 451 AIAIFTAAAWAYMVLFLFLGP 471
                 455788888888888888886 PP

>> MFS_4  Uncharacterised MFS-type transporter YbfB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.1   0.4   1.3e-09   4.8e-06      43     174 ..     107     238 ..      82     267 .. 0.80

  Alignments for each domain:
  == domain 1  score: 26.1 bits;  conditional E-value: 1.3e-09
       MFS_4  43 vGallaafalsagaeRlrllagllatvllllamaltesfaaflliRflaGvasAvvlvfgsslvlahaaaarrervgallfaGvGlGiavsgllvllll 141
                 vGall+ +   +   R  + a l++  +l la+++ +s+  f+ +R l G+a +  +   ++++l+ + a  r+ + +++ +G  +G ++++++  +l+
  EEA18691.1 107 VGALLFGTLCDRYGRRWPMIANLVLLIVLELASGFCSSLHQFIGVRSLYGIAMGGLIGPCAAIALEDLPADARGLLSGVFEGGTAIGNLIASTMYRALV 205
                 8*****888888888888*********************************************************************888877766555 PP

       MFS_4 142 qlglsasslWlalavlsavllllvalllpraal 174
                  +  ++  + +++++   +l+++  ++lp++ +
  EEA18691.1 206 PTTKHGWRSLYWFGAGPPILIIIFRWWLPETDH 238
                 554444444455555578888888888884433 PP

>> ATG22  Vacuole effluxer Atg22 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.1     0.063   2.2e+02     432     460 ..     107     135 ..      72     163 .. 0.71
   2 !   21.5   0.8   2.1e-08   7.6e-05     274     367 ..     271     367 ..     192     391 .. 0.79

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.063
       ATG22 432 igplivglItDrtgnirsafvflavLlvv 460
                 +g l++g + Dr+g  ++ +  l++L+v+
  EEA18691.1 107 VGALLFGTLCDRYGRRWPMIANLVLLIVL 135
                 46677777777777655444444444444 PP

  == domain 2  score: 21.5 bits;  conditional E-value: 2.1e-08
       ATG22 274 tlkqarklkdvllfLvawfllsdgiatvsstav....lfaktelkmstaklillsivaviaavlGaflwplvsrrlnlktkktllaiivlfeliplyG 367
                 +  +a+++k+  l L+  fll +g++  +  a+    +f k+++++ + +++++si+  + a++G +++ ++s  l+ +  ++++ +iv  +++p+y 
  EEA18691.1 271 IYDSAKSVKENWLLLLYMFLLMTGFNACVHGASdlypTFLKNQVQLDAEHMAIVSIMGNLGACFGGITLGYISGFLGRR-LTMICGCIVGSAILPAYI 367
                 347788899999999999***999998655443333399*************************************999.9***************95 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.4   1.9e-05     0.068     233     374 ..      57     201 ..      18     208 .. 0.85
   2 !    3.7   0.2    0.0065        23      26      82 ..     310     367 ..     283     374 .. 0.90
   3 ?   -1.6   0.0      0.26   9.4e+02      66      95 ..     451     480 ..     440     488 .. 0.60

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 1.9e-05
  MFS_1_like 233 valilgmswgiienF........lflYLkelgasntllGslvalgvvaeiplfffaeklleklGhvklliiallayilrfllyaiienawlvlpievLh 323
                  ++++gm+  + ++F        ++    + +a+ + +  +++++ ++  +  ++   l +++G ++ +i+ l++ i+  l  ++++++   + +  L+
  EEA18691.1  57 LMFLCGMCGRAWDAFdyttvpltVTELAAQFDAPDSAVTWAITVTLMMRPVGALLFGTLCDRYGRRWPMIANLVLLIVLELASGFCSSLHQFIGVRSLY 155
                 4677777777777777789998655555899999999999999999999888888889*********************999***************** PP

  MFS_1_like 324 gisfgllwaaaveyvskiapksleatgqgllsglyfglGralGsliGGllw 374
                 gi++g l    +  ++ ia + l a   gllsg++ g G+a+G+li+  ++
  EEA18691.1 156 GIAMGGL----IGPCAAIALEDLPADARGLLSGVFEG-GTAIGNLIASTMY 201
                 *****99....66777788899999999999999776.9******998887 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.0065
  MFS_1_like  26 lk.skglkaseigiitlilpltsilsppiwgvlaDrfgkrkkvvilslllsavlflsl 82 
                 lk + +l+a+  +i++ +  l + ++   +g ++  +g+r +++  +++ sa+l + +
  EEA18691.1 310 LKnQVQLDAEHMAIVSIMGNLGACFGGITLGYISGFLGRRLTMICGCIVGSAILPAYI 367
                 443899**********************************************997755 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 0.26
  MFS_1_like  66 kvvilslllsavlflsllfippskerqees 95 
                 +++i+++ ++a ++l l++ p+ ++++e +
  EEA18691.1 451 AIAIFTAAAWAYMVLFLFLGPEASRDEEVQ 480
                 466666666666666556556555555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (527 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       702  (0.0391544); expected 358.6 (0.02)
Passed bias filter:                      534  (0.0297841); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.78u 0.39s 00:00:01.17 Elapsed: 00:00:00.59
# Mc/sec: 2694.57
//
Query:       EEA18692.1  [L=484]
Description: monocarboxylate permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      8e-33  113.8  53.1    1.2e-31  110.0  40.2    2.1  2  MFS_1     Major Facilitator Superfamily
    2.2e-08   33.4  30.7    1.4e-05   24.2   9.7    2.2  2  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.0  40.2   1.3e-35   1.2e-31       6     325 ..     100     408 ..      93     419 .. 0.82
   2 !   11.8   8.8     9e-06     0.081       4      81 ..     389     468 ..     386     482 .. 0.61

  Alignments for each domain:
  == domain 1  score: 110.0 bits;  conditional E-value: 1.3e-35
       MFS_1   6 flsalarsilgpalplalaedlg.............ispseigllltlyalgaavaslplGrlsdrfGrrr.vlllglllfalglllllfa..sslw.l 87 
                 fl  +a++  + ++        g             +s + +g++ + + ++a+++ + +G+l d +G++  v+  +++++++  ll+  a   ++w +
  EEA18692.1 100 FLLLMASYGMMNSV--------GvfqsyletnqlssYSSADVGWIPSSFVFVALLLGVYVGPLFDSHGPKLlVYGGSVIFMVSL-LLF--AecRHYWqF 187
                 33333333333333........2222222244566789999******************************6666666666666.444..33589999* PP

       MFS_1  88 llvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspke 186
                 ll + v+ G+ga+++ ++++a + +wf   + g+aig + ag++lG i+ p +  +  s++g+ +++ +la+v  ++++l+ + ++++ p++k ++ + 
  EEA18692.1 188 LLSFGVIGGIGAALVSTVAMACVPHWFEI-RAGMAIGTALAGSGLGGIVFPFVMRAGFSNIGFKWTMRVLAFVVGFLCLLGSFMVRARLPKKKSSKAVI 285
                 *****************************.*************************************************98888888888888887777 PP

       MFS_1 187 eekgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlllalllll 285
                 +            ++ ++  ++ w+ l +++l  + +++ll + p+y     g+s   l+++ll +l ++g i++l+agr++dr+gr ++l++a++l++
  EEA18692.1 286 D------------LRCFKDLKFTWMTLSTFCLE-LQYFSLLGMYPIY-IIAQGFS-TDLSVILLVILNVFGTIGRLIAGRIADRYGRLNTLTVAVFLTT 369
                 7............9999999999*555555555.69999********.*******.688888899999999999************************* PP

       MFS_1 286 laalglallavtssavllllvlvliGfglgfvfpsllala 325
                 l+++ l++     s ++l++++ l+G++++ + + + +++
  EEA18692.1 370 LWLFVLLYPFQK-SVPVLYVFSCLYGLTASAFISVSPVCI 408
                 **9999999988.777777788889995555555555554 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 9e-06
       MFS_1   4 aaflsalarsilgpalplalaedlgispseigl....lltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllf 81 
                   +l++l++s+++++ p ++ +   +++ eigl     +++++++ +v+++++G l++r G++ +++++ +l++ +++ll++
  EEA18692.1 389 FSCLYGLTASAFISVSPVCIRQI--SDAKEIGLrfgtCYSVVSFALLVSIPVTGELMQRGGPKAMIIWSGALLVWSSFLLAL 468
                 45777777777777777777666..567776665333445555566778888888888888888666666555555344443 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3  15.6   1.6e-06     0.014       7     185 ..      97     268 ..      92     277 .. 0.78
   2 !   24.2   9.7   1.6e-09   1.4e-05      18     187 ..     259     468 ..     255     473 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 1.6e-06
                 HHH.HHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TG CS
    Sugar_tr   7 lgg.llfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvev 104
                 lg+ ll    +g+++++  +++++  ++ls+++s+      ++g+i s+f+++a++ ++++g+l d  G k     ++v+f+++ +l a +    ++++
  EEA18692.1  97 LGSfLLLMASYGMMNSVGVFQSYLETNQLSSYSSA------DVGWIPSSFVFVALLLGVYVGPLFDSHGPKLLVYGGSVIFMVSLLLFAECR---HYWQ 186
                 55544555556677777777776666666666664......569************************************************...8888 PP

                 GGGG.HHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHH CS
    Sugar_tr 105 livg.RvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallll 185
                 ++++  v+ Gig+ l+s+++   +      +   a+++    +   Gi++ +++ +g+++++ ++++r+l ++  ++ ll +
  EEA18692.1 187 FLLSfGVIGGIGAALVSTVAMACVPHWFEIRAGMAIGTALAGSGLGGIVFPFVMRAGFSNIGFKWTMRVLAFVVGFLCLLGS 268
                 8877699999*99999988877777666666666667777777778888999999999888877888888888777775554 PP

  == domain 2  score: 24.2 bits;  conditional E-value: 1.6e-09
                 CGGGTHHHHHHHHTSTT--SHHHHHH............................................HHHHHHHTHHHHHHHHHHHHHHHHHHTTH CS
    Sugar_tr  18 vigafltllkfaknfglsksksskee.........................................ssvlsglivsiflvGaiiGslfagllgdrfGR 75 
                 v+g+   l +f  +  l k+kssk+                                          s+ ls +++ i++v ++iG l+ag ++dr+GR
  EEA18692.1 259 VVGFLCLLGSFMVRARLPKKKSSKAVidlrcfkdlkftwmtlstfclelqyfsllgmypiyiiaqgfSTDLSVILLVILNVFGTIGRLIAGRIADRYGR 357
                 666777777777777788888777668888888888888888888888999999999999999999999999999************************ PP

                 HHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHH.HTSS-TTHHHHH CS
    Sugar_tr  76 kkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglgl.nktsnadgwril 173
                  ++l +a++l+    ++      ++sv vl+v   l G+ + ++  ++P+ i  i+ +k  g   +   + ++f  lv++ ++  l ++ +  + + i 
  EEA18692.1 358 LNTLTVAVFLTTLWLFVLLYPF-QKSVPVLYVFSCLYGLTASAFISVSPVCIRQISDAKEIGLRFGTCYSVVSFALLVSIPVTGELmQRGGP-KAMIIW 454
                 **********999888888888.55*******************************888777655555567899999999999988455555.999999 PP

                 HHCCHHHHHHHHHH CS
    Sugar_tr 174 lglqlvpallllil 187
                  g  lv++ +ll+l
  EEA18692.1 455 SGALLVWSSFLLAL 468
                 99999999888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (484 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       688  (0.0383736); expected 358.6 (0.02)
Passed bias filter:                      253  (0.0141112); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.73u 0.36s 00:00:01.08 Elapsed: 00:00:00.57
# Mc/sec: 2579.28
//
Query:       EEA18693.1  [L=289]
Description: hypothetical protein PMAA_009760 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.6e-08   32.0  28.0      0.023   14.5   1.3    5.0  4  AT_hook   AT hook motif


Domain annotation for each model (and alignments):
>> AT_hook  AT hook motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.4   1.5   6.3e-06      0.11       2       9 ..      40      47 ..      39      50 .. 0.89
   2 !   10.7   1.3   2.2e-05       0.4       2      11 ..      61      70 ..      60      71 .. 0.87
   3 !   14.5   1.3   1.3e-06     0.023       2      12 ..      88      98 ..      88      99 .. 0.91
   4 !   10.0   2.3   3.7e-05      0.66       2      11 ..     100     109 ..      99     110 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 6.3e-06
     AT_hook  2 RkRGRPrK 9 
                +kRGRPrK
  EEA18693.1 40 KKRGRPRK 47
                9******9 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 2.2e-05
     AT_hook  2 RkRGRPrKaa 11
                ++RGRP+K++
  EEA18693.1 61 KRRGRPAKDS 70
                99******86 PP

  == domain 3  score: 14.5 bits;  conditional E-value: 1.3e-06
     AT_hook  2 RkRGRPrKaat 12
                +kRGRP+Kaat
  EEA18693.1 88 KKRGRPAKAAT 98
                8********98 PP

  == domain 4  score: 10.0 bits;  conditional E-value: 3.7e-05
     AT_hook   2 RkRGRPrKaa 11 
                 +kRGRP+K++
  EEA18693.1 100 GKRGRPAKTK 109
                 69******97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (289 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       960  (0.0535445); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.66u 0.38s 00:00:01.04 Elapsed: 00:00:00.56
# Mc/sec: 1556.71
//
Query:       EEA18694.1  [L=203]
Description: phosphatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-11   43.9   0.0    1.5e-09   37.9   0.0    2.3  1  Macro     Macro domain


Domain annotation for each model (and alignments):
>> Macro  Macro domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.9   0.0   8.6e-14   1.5e-09       1     117 [.      20     179 ..      20     180 .. 0.76

  Alignments for each domain:
  == domain 1  score: 37.9 bits;  conditional E-value: 8.6e-14
                 EEEEETTSS-CSHHHHHHHHHHHHHHHHHHHHHHHHHHS..................--TTSEEEEE-TTSS...........SSEEEEEESE-TTTS. CS
       Macro   1 VnAaNsrllggggvagaihraagkalkeeckelekkqgg..................cllGeavvtpaynlp...........akyvihtvgplftss. 69 
                 ++A+N+ +++ggg+a+++++++++a++ + +++++  ++                  ++lG+a+++p    +                h + +lfts  
  EEA18694.1  20 IHACNCLGSWGGGIAKVFQNKYPEAYRIYNTHCRTLLKQkrahtlehsttndaktvyLPLGTALIIPPQPRDyaasasnrgkdK--KKHWIVCLFTSRa 116
                 7****************************9999775333346788888888888888889999998866555555566677543..3344447888777 PP

                 ..TSTTHHHHHHHHHHHHHHHHHHTT-S.............EEEEE-TTSSTTSBTHHHHHHH CS
       Macro  70 ..kskeeeellakayknalelaeekgik.............svafPaistGifgvpweeaarv 117
                   ++ ++++ + ++  +a+++ +++  +             +v  +  ++G+fgv+w+ + rv
  EEA18694.1 117 ygRGVSKPDIILENSVHAIRDMRRELEElfenndeagkwdgKVYSCRFNSGLFGVDWKASKRV 179
                 77778888888888888888843333335557777899999*****************99987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (203 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       586  (0.0326845); expected 358.6 (0.02)
Passed bias filter:                      544  (0.0303419); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.32s 00:00:00.93 Elapsed: 00:00:00.54
# Mc/sec: 1139.45
//
Query:       EEA18695.1  [L=303]
Description: dihydrodipicolinate synthetase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-48  164.5   0.1    2.5e-48  164.3   0.1    1.0  1  DHDPS     Dihydrodipicolinate synthetase family


Domain annotation for each model (and alignments):
>> DHDPS  Dihydrodipicolinate synthetase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  164.3   0.1   1.4e-52   2.5e-48       3     259 ..       7     269 ..       5     294 .. 0.89

  Alignments for each domain:
  == domain 1  score: 164.3 bits;  conditional E-value: 1.4e-52
                 SEEEEE----B-TTSSB-HHHHHHHHHHHHHCT-SEEEESSCCCTGGGS-HHHHHHHHHHHHHHHT....TSSEEEEE---SSHHHHHHHHHCCCCCT- CS
       DHDPS   3 sgiitalvtpfdedgkldkealrklieflinkgvdglvvaGttGEsatlsteekeqlveiaveaak....gripviagvGsnstseaiklakkaeeaGa 97 
                 +gi ++ v+ fd + ++d +  +k +  l ++gv g+vv G+ GE+  l  +e++ +   +++a +    ++ pvi g+G++st+e i l+k a+eaGa
  EEA18695.1   7 GGIYVPTVAFFDSNEEVDTATTEKHAVNLAKAGVAGIVVQGSNGEAVHLDRAERKLITSLTRKALDaagfEKLPVIVGTGAQSTRETILLSKDAAEAGA 105
                 689999************************************************988777777666333569*************************** PP

                 SEEEEE---SS---HH..HHHHHHHHHHHCHSS-EEEEE-HHHH.SHHHHHHHHHHHHTSTTEEEEEE-SS-CTHHHHHHCCCSTTSEEEES-GGGHHH CS
       DHDPS  98 dgvlavtPYYnkpsqe..glyqhfkaiieatdlpvilYnvpsrt.gadlspetvkrLaelenivgvKeavgdleevikikkevgkdlviysGddellls 193
                 d v+a++P Y+k +       q+fk ++ a   pv++Yn+p+ + g+dl+ + + +L++  ni+gvK + g++ ++ +i ++v++ ++ + G  + +l+
  EEA18695.1 106 DYVIALPPSYYKGQDTssSRLQYFKDVADASPIPVLIYNFPGAAnGVDLNSDEIIELSQHTNIIGVKLTCGNTGKLARIAANVKPGFLTLGGSCDFILQ 204
                 ***********99765115679******8888*********86438***************************************************** PP

                 HHHTT-SEEEESCHHCHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHCCCCSCCHHHHHHHHCT CS
       DHDPS 194 alslGadGvisvtsniagermrqlikalkeGdlaeaaelnekllplikilfaepnvilvktalell 259
                 +l +G++Gvi+ t+ni+++   q++k++++G+laea++l++ + +  +++  ++ +  vk+al+  
  EEA18695.1 205 TLIAGGQGVIAGTANIIPRTCVQVYKLYEDGKLAEAQKLQALVAR-ADWVCIQGGFPSVKAALQAF 269
                 ***************************************986666.78888888888899999865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (303 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       395  (0.0220313); expected 358.6 (0.02)
Passed bias filter:                      356  (0.0198561); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1998.79
//
Query:       EEA18696.1  [L=383]
Description: mandelate racemase/muconate lactonizing enzyme family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-53  182.0   0.1    1.5e-53  181.6   0.1    1.1  1  MR_MLE_C  Enolase C-terminal domain-like
    2.7e-19   69.5   0.0    5.1e-19   68.6   0.0    1.4  1  MR_MLE_N  Mandelate racemase / muconate lactonizing enzyme, N


Domain annotation for each model (and alignments):
>> MR_MLE_C  Enolase C-terminal domain-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  181.6   0.1   1.7e-57   1.5e-53       6     219 ..     133     356 ..     128     357 .. 0.93

  Alignments for each domain:
  == domain 1  score: 181.6 bits;  conditional E-value: 1.7e-57
                 HHHHHHHHT-SEEEEETSSS........HHHHHHHHHHHHHHHHTTTSTSEEEEE-TTTSBHHHHHHHHHHHGGGTESEEESSSSTTTHHHHHHHHHH. CS
    MR_MLE_C   6 arelvaeqgfravKlkvggd........dvaedvervravreavgpgddvdlmvDanqawdlatAirvareleeldllwlEEPvppeddleglaelra. 95 
                 a +++ +qg + +K++ ++d         ++  ver++av+ a+  g   d  +D++++++ ++A ++a++le++++l++EEP+  e+ +e++++l+  
  EEA18696.1 133 A-KARIAQGLKCIKMNATEDvnwvdspsVLDSTVERLKAVK-AL--GL--DAGLDFHGRLHKPMAKQLAKALEPHRPLFIEEPLLCEH-PEAIKQLSGl 224
                 3.334557********9999*******99*********886.55..66..88********************99************76.********74 PP

                 HHSSEEEESTTSSSHHHHHHHHHHTSESEEEEBHHHHTSHHHHHHHHHHHHHTT-EEEEBSCSSHHHHHHHHHHHHTTTTBEEEEEEGGGGH....... CS
    MR_MLE_C  96 rasipiaagEslysradfrelleagavdivqpdvsrvgGitearkvaalaeafgvpvapHsgsgglglaaslhlaaaipnllileyfldael....... 187
                 + +ipia gE+ly+r+d++++le++ vdi+qpd++++gGi+e+r++a++aea++v +apH++ g++++aas+++a  ipn+ i+e++l+ ++       
  EEA18696.1 225 T-TIPIAFGERLYTRWDVKKFLEDHSVDILQPDIAHAGGISETRRIANIAEAYDVAIAPHCPLGPIAFAASVQVALNIPNFVIQEMSLGMHYnveagdi 322
                 3.89*********************************************************889*********************************** PP

                 ..TSGCSBSSSSEEETTEEECTSSSBTSSEB-HH CS
    MR_MLE_C 188 ..leeelleeplevedGrvtvpdgpGlGveldee 219
                    ++   ++ + +e+G+v++p+g GlG+e+de+
  EEA18696.1 323 dlNTYLKDQSVFAIEEGYVKAPTGAGLGIEIDED 356
                 *999999999**********************97 PP

>> MR_MLE_N  Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.6   0.0   5.6e-23   5.1e-19      27     117 .]      15     108 ..      10     108 .. 0.96

  Alignments for each domain:
  == domain 1  score: 68.6 bits;  conditional E-value: 5.6e-23
                 EEEEEEEEECTTEEEEEEEE-STTGHHHHHHHHHHHHHHHHTTSBTTHHHHHHHHHHHHCSS.....CHHHHHHHHHHHHHHHHHHTTSBHHHHTT CS
    MR_MLE_N  27 slvlvkietseGvvGigeatsvggraetikaelddhlapllvgkdaanisdlaqllkravlg.....nmsAkaaidmAlwDlkakalnlpladLlG 117
                 +  +vki+ ++G  G+ge+t++g  +++++ +ld+ ++  l+g +a+ i++++q++ r  ++      msA ++id+AlwDlk++ l++p+++LlG
  EEA18696.1  15 RWLFVKITDEKGGYGWGEGTLEG-HDLAVEGALDE-MITRLIGYEADDIEHIWQTIWRLGFYrggpvFMSALSGIDIALWDLKGRNLGVPVYQLLG 108
                 6779*******************.*********99.9***********************9999**9****************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (383 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       317  (0.0176809); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.25s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2673.33
//
Query:       EEA18697.1  [L=268]
Description: gluconate 5-dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.2e-50  170.3   0.0    4.3e-50  169.9   0.0    1.2  1  adh_short       short chain dehydrogenase
    2.8e-49  167.8   0.2    5.7e-49  166.8   0.2    1.4  1  adh_short_C2    Enoyl-(Acyl carrier protein) reductase
      6e-13   49.1   1.0    1.1e-12   48.2   0.1    1.7  2  KR              KR domain
    1.8e-05   24.3   0.1    2.5e-05   23.9   0.1    1.3  1  Epimerase       NAD dependent epimerase/dehydratase family
    0.00064   19.5   0.0      0.062   13.0   0.0    2.8  3  Glyco_transf_5  Starch synthase catalytic domain
  ------ inclusion threshold ------
      0.014   14.8   0.1      0.021   14.3   0.1    1.2  1  GDP_Man_Dehyd   GDP-mannose 4,6 dehydratase
      0.034   14.1   0.0          4    7.4   0.0    2.9  3  Glyco_transf_4  Glycosyltransferase Family 4
      0.044   14.2   0.0      0.092   13.2   0.0    1.5  1  NAD_binding_7   Putative NAD(P)-binding
       0.05   13.0   0.1      0.076   12.4   0.1    1.2  1  PALP            Pyridoxal-phosphate dependent enzyme
      0.093   12.3   0.9       0.16   11.5   0.9    1.4  1  NmrA            NmrA-like family
        0.1   12.2   0.0       0.16   11.6   0.0    1.3  1  ApbA            Ketopantoate reductase PanE/ApbA


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  169.9   0.0   2.6e-53   4.3e-50       2     190 ..      13     214 ..      12     219 .. 0.97

  Alignments for each domain:
  == domain 1  score: 169.9 bits;  conditional E-value: 2.6e-53
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCSHHH CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfselseee 100
                 ++lvtG+++GIG ++a +la++Ga+v++v+r  +  +++++ ++++g+ka+++++D+++re+v+ l +k+ ++   + +L+++AGi++++p++++ +++
  EEA18697.1  13 TALVTGGTRGIGAQVAIALAEAGADVILVQRDTS-SQQTKQTIESLGRKAFIYTADLSSREDVSGLTKKVLADGHDVSILITCAGIQRRHPAEKFPDSD 110
                 89*****************************966.679************************************************************* PP

                 HHHHHHHHTHHHHHHHHHHHHHHH..............HCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSH CS
   adh_short 101 wervievNltgvflltravlpaml..............kqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTd 185
                 w++v++vNlt vf l+r +  +ml               + +G+I+nv+S +++++ + v+aY+++K+++a+lt++l++e+a++g++vna+aPG+++Td
  EEA18697.1 111 WDEVLQVNLTTVFTLCRDIGAYMLtrppfpgtestspgGGYRGSIINVASLVSFQGGITVPAYASAKGGIAQLTKALSNEWASKGVNVNAIAPGYIATD 209
                 ********************************9999988999********************************************************* PP

                 HHHHH CS
   adh_short 186 makel 190
                 m+++l
  EEA18697.1 210 MNEAL 214
                 *9876 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  166.8   0.2   3.5e-52   5.7e-49       3     233 ..      20     265 ..      18     266 .. 0.95

  Alignments for each domain:
  == domain 1  score: 166.8 bits;  conditional E-value: 3.5e-52
                   TTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSE.E.EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHHH CS
  adh_short_C2   3 asgIGraiAkalaeeGaevvltdlneeakkrveelaeelgae.v.lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreefdr 97 
                    +gIG+++A alae+Ga+v+l++++ ++ +++++  e+lg++ + + +D +++e+v  l ++v ++   + il+ +agi ++   p+++++++++d+
    EEA18697.1  20 TRGIGAQVAIALAEAGADVILVQRDTSS-QQTKQTIESLGRKaFiYTADLSSREDVSGLTKKVLADGHDVSILITCAGIQRR--HPAEKFPDSDWDE 113
                   69***********************999.8899999999988536*************************************..************* PP

                   HHHHHTHHHHHHHHHHHHHCTSC................CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTG CS
  adh_short_C2  98 aldvnlyslfllakaalplmkeg................gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTla 178
                   +l+vnl+ +f l++ +  +m  +                gsi+n++s+ + ++     ay+ aK+++ +lt++l +e+++kg+ vNa++pg+i+T++
    EEA18697.1 114 VLQVNLTTVFTLCRDIGAYMLTRppfpgtestspgggyrGSIINVASLVSFQGGITVPAYASAKGGIAQLTKALSNEWASKGVNVNAIAPGYIATDM 210
                   *****************9654444677788899999************************************************************* PP

                   GGGSTTHHHHHHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEESTTG CS
  adh_short_C2 179 asgikgfdelleelearaplgrlgtpeevaeaalfLasdeasyitGqtlvvDgGl 233
                   ++++ +++   e++  r+p gr+g++e+    ++fLa  ++ y++G++l vDgG+
    EEA18697.1 211 NEALINNPTRAEQILVRIPAGRWGNAEDFKGPTVFLAGRASLYVSGEILTVDGGW 265
                   ******************************************************7 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.2   0.1   6.9e-16   1.1e-12       2     116 ..      13     122 ..      12     129 .. 0.89
   2 ?   -1.1   0.1      0.97   1.6e+03     144     174 ..     168     202 ..     155     210 .. 0.52

  Alignments for each domain:
  == domain 1  score: 48.2 bits;  conditional E-value: 6.9e-16
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT- CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklleem 100
                 t l+tGG+ g+G ++a  lae ga  ++l+ R+ +   +s+++ +++e+lg +  ++ aD+s++++v+ l +++ a+++ ++  i +Ag+ r ++ e+ 
  EEA18697.1  13 TALVTGGTRGIGAQVAIALAEAGAD-VILVQRD-T---SSQQTKQTIESLGRKAFIYTADLSSREDVSGLTKKVLADGHDVSILITCAGIQRRHPAEKF 106
                 579********************96.6778888.3...34445578889999*********************************************** PP

                 -HHHHHHHHTTTTHHH CS
          KR 101 taedleqvlapKvkGa 116
                  ++d+++vl+  ++ +
  EEA18697.1 107 PDSDWDEVLQVNLTTV 122
                 *********9876665 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.97
                 TT-HHHHHH....HHHHHHHHHHHHHHHHTEEEEE CS
          KR 144 agqanYaaa....NaflDalaeyrrsqglpavsin 174
                  +  +Ya+a     +   al ++++s+g ++ +i+
  EEA18697.1 168 ITVPAYASAkggiAQLTKALSNEWASKGVNVNAIA 202
                 55555555522222344555555555555555554 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.1   1.5e-08   2.5e-05       1      73 [.      14      96 ..      14     203 .. 0.69

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 1.5e-08
                EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC.....EEEE--TT-HHHHHHHHHH....H.T-SEEEE--S CS
   Epimerase  1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl.....elveldltdrsalerlfke....e.qpdavihlAa 73
                +lVtG+t  iG++++ al+e+g +vi ++r++s+++t++  +       ++++dl  r+++  l k+      ++ + i +A+
  EEA18697.1 14 ALVTGGTRGIGAQVAIALAEAGADVILVQRDTSSQQTKQTIESlgrkaFIYTADLSSREDVSGLTKKvladGhDVSILITCAG 96
                59*******************************99999877778***9999********877666551111235556666666 PP

>> Glyco_transf_5  Starch synthase catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.13   2.1e+02       9      56 ..      11      57 ..       6      72 .. 0.70
   2 ?    1.2   0.0      0.15   2.4e+02      22      50 ..      74     101 ..      72     139 .. 0.64
   3 !   13.0   0.0   3.8e-05     0.062      14      50 ..     176     213 ..     168     253 .. 0.78

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.13
  Glyco_transf_5  9 vaplaktGGLadvvgaLpkaLaklghdvrvilPrygaikeekkeleev 56
                    +     tGG   + ++ + aLa++g dv ++  + ++ + ++ ++e++
      EEA18697.1 11 NRTALVTGGTRGIGAQVAIALAEAGADVILVQRDTSSQQTKQ-TIESL 57
                    5555667777777789999******99999988884444443.44444 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.15
  Glyco_transf_5  22 vgaLpkaLaklghdvrvilPrygaikeek 50 
                     v++L k+  + ghdv++++     i++++
      EEA18697.1  74 VSGLTKKVLADGHDVSILITCA-GIQRRH 101
                     5789999999******999554.555554 PP

  == domain 3  score: 13.0 bits;  conditional E-value: 3.8e-05
  Glyco_transf_5  14 ktGGLadvvgaLpkaLaklghdvrvilPry.gaikeek 50 
                       GG+a+ ++aL+++ a +g++v  i P+y  +  +e+
      EEA18697.1 176 AKGGIAQLTKALSNEWASKGVNVNAIAPGYiATDMNEA 213
                     56****************************54444433 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.1   1.3e-05     0.021       1      74 [.      15      81 ..      15      85 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 1.3e-05
                   EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TT.HHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHHHH CS
  GDP_Man_Dehyd  1 LiTGiaGfiGsylaelLlekgyevhgivrrsssfnt.griehlakdpkeeleenlklhkgDltDssslerllaev 74
                   L+TG++  iG+ +a  L e g +v+ + r++ss +t ++ie+l +        + +++ +Dl+ ++ +  l ++v
     EEA18697.1 15 LVTGGTRGIGAQVAIALAEAGADVILVQRDTSSQQTkQTIESLGR--------KAFIYTADLSSREDVSGLTKKV 81
                   9**************************999998877245666653........4578888888888888777765 PP

>> Glyco_transf_4  Glycosyltransferase Family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.0      0.22   3.5e+02      10      33 ..      26      49 ..      18      69 .. 0.75
   2 ?    1.9   0.0      0.12   1.9e+02      11      38 ..      77     109 ..      74     140 .. 0.71
   3 ?    7.4   0.0    0.0025         4       2      38 ..     178     216 ..     177     247 .. 0.76

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.22
  Glyco_transf_4 10 eLaraLarrGheVtvvtpgddgpl 33
                    ++a aLa++G +V +v ++++  +
      EEA18697.1 26 QVAIALAEAGADVILVQRDTSSQQ 49
                    56889**********965555444 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.12
  Glyco_transf_4  11 LaraLarrGheVtvv..tpgddgpleeev...e 38 
                     L++   ++Gh+V+++  + g +++++ e     
      EEA18697.1  77 LTKKVLADGHDVSILitCAGIQRRHPAEKfpdS 109
                     66777899*******987777777777655551 PP

  == domain 3  score: 7.4 bits;  conditional E-value: 0.0025
  Glyco_transf_4   2 GGverhvleLaraLarrGheVtvvtpgddgpleeev..e 38 
                     GG++  +  L++++a +G++V  ++pg+     +e    
      EEA18697.1 178 GGIAQLTKALSNEWASKGVNVNAIAPGYIATDMNEAliN 216
                     9**************************998888884441 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   5.6e-05     0.092       4      54 ..       8      61 ..       6     108 .. 0.67

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 5.6e-05
  NAD_binding_7  4 dlkgkkvlvvGgGe.vAarkvrklleagakvtvvapev.keeleelvk.laeee 54
                    l++++ lv Gg + ++a+ +  l+eaga+v++v  ++ +++++++++ l ++ 
     EEA18697.1  8 SLENRTALVTGGTRgIGAQVAIALAEAGADVILVQRDTsSQQTKQTIEsLGRKA 61
                   689********99669********************964334444444222222 PP

>> PALP  Pyridoxal-phosphate dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   4.7e-05     0.076      57     117 ..      14      74 ..       8      97 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 4.7e-05
                 EEEEEBSSHHHHHHHHHHHHHT-EEEEEEETTS-HHHHHHHHHTT-EEEEECCHHHHHHHH CS
        PALP  57 tvveassGNhgralAaaaallGlkvtivvpadaspekvallrllGaevvevggdydeavaa 117
                  +v++++   g+ +A+a a +G +v++v  +++s++ ++ +++lG +   +  d  +++++
  EEA18697.1  14 ALVTGGTRGIGAQVAIALAEAGADVILVQRDTSSQQTKQTIESLGRKAFIYTADLSSREDV 74 
                 555666666899*********************************9998887775555544 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.9   9.7e-05      0.16       2      62 ..      15      78 ..      14      93 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 9.7e-05
                EESSTTSHHHHHHHHHHHHHT-EEEEEES-S.-SHHHHHHHHSTTE.EE.ES-TT-HHHHHHHH CS
        NmrA  2 lviGaTGrqGksvvrallkaghkvralvRdt.kselakslkeaGve.lv.kgdlddkeslveal 62
                lv+G+T  +G++v+ al++ag +v  + Rdt ++++ +++++ G + ++  +dl ++e ++ + 
  EEA18697.1 15 LVTGGTRGIGAQVAIALAEAGADVILVQRDTsSQQTKQTIESLGRKaFIyTADLSSREDVSGLT 78
                79*****************************434445567777754134567776666665555 PP

>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   9.7e-05      0.16       8      38 ..      22      52 ..      17      94 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 9.7e-05
                HHHHHHHHHHHHHTHCEEEE-SCHHHHHHHH CS
        ApbA  8 aiGsllaakLakagadvtlilrsrrlealkk 38
                +iG  +a  La+agadv+l+ r+   ++ k+
  EEA18697.1 22 GIGAQVAIALAEAGADVILVQRDTSSQQTKQ 52
                79********************995544443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (268 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       573  (0.0319594); expected 358.6 (0.02)
Passed bias filter:                      522  (0.0291148); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.57u 0.31s 00:00:00.87 Elapsed: 00:00:00.51
# Mc/sec: 1593.02
//
Query:       EEA18698.1  [L=621]
Description: hypothetical protein PMAA_009810 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.2e-16   59.1   2.7    1.2e-15   57.2   2.7    2.1  1  Fungal_trans_2  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.2   2.7   6.7e-20   1.2e-15       2     132 ..     189     333 ..     188     561 .. 0.81

  Alignments for each domain:
  == domain 1  score: 57.2 bits;  conditional E-value: 6.7e-20
  Fungal_trans_2   2 lldyyldnvapllspvpes......snpfrkvllplalsnkallhallalsafhl.qskgpkdslereakrykslalkelqealaelsstlsrne 89 
                     ll+++l++ a  ++  + +       np r+v +pl lsn a ++ ++a +a+hl   +g+kd    e+++yks+a++++++ +++ ++ l    
      EEA18698.1 189 LLHHWLTSHAAMMFDTDTPsslnlnFNPMRDVWFPLDLSNAASFYGMMAHAAAHLaYLHGQKD--AVEVLKYKSEAVSLINHWMQDEKTALG--- 278
                     7888888888888877777778899******************************77777777..99*************************... PP

  Fungal_trans_2  90 kykdiLaaiLllcsieissgdvsdwrvhLeaatsliksrggs..............k 132
                       ++++aa+  l s+e ++g++  wr+h ++  ++i+ rgg+              +
      EEA18698.1 279 --DATFAAVVRLLSFERYWGTEAVWRIHRDGLDRMIQARGGLaslkqnwrlglvlqL 333
                     ..****************************************444444444443330 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (621 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1125  (0.0627475); expected 358.6 (0.02)
Passed bias filter:                      619  (0.0345251); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.72u 0.32s 00:00:01.04 Elapsed: 00:00:00.50
# Mc/sec: 3769.79
//
Query:       EEA18699.1  [L=466]
Description: cell wall serine-threonine-rich galactomannoprotein Mp1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.5e-46  156.5   5.6    2.4e-22   79.6   0.0    3.7  4  HsbA             Hydrophobic surface binding protein A
  ------ inclusion threshold ------
        0.1   12.2   0.6          4    7.1   0.0    2.9  3  ThylakoidFormat  Thylakoid formation protein
       0.15   12.2   1.2       0.62   10.2   0.6    2.0  2  AAA_lid_10       AAA lid domain
       0.26   11.4   2.4       0.58   10.3   0.6    2.2  2  Flagellin_N      Bacterial flagellin N-terminal helical regio
       0.85    9.7   4.2        2.6    8.1   0.4    2.9  3  DUF1664          Protein of unknown function (DUF1664)


Domain annotation for each model (and alignments):
>> HsbA  Hydrophobic surface binding protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.6   0.0   6.8e-26   2.4e-22       3     119 ..      35     150 ..      33     151 .. 0.96
   2 ?    2.2   0.1     0.064   2.3e+02      16      46 ..     170     201 ..     157     202 .. 0.77
   3 !   76.1   0.3   8.3e-25     3e-21       2     118 ..     201     316 ..     200     318 .. 0.96
   4 ?   -2.4   0.0       1.7   6.1e+03      38      59 ..     332     353 ..     329     359 .. 0.76

  Alignments for each domain:
  == domain 1  score: 79.6 bits;  conditional E-value: 6.8e-26
                 HHHHHHHHHHHHHHHHHHHHHH--SH..HHHHHHHHHHHHHHHHHHHHHHHTS----HHHHHHHHHHHHHCHHHHHHHHHHHHHTHHHHHHHT-HHHHH CS
        HsbA   3 tvisdittistavtaldtavnafnGgasalpilsasnalvsaikkattdaqasapltdeealalaqavqtLepdvkaaldaliaKkpafdkagltslvl 101
                  ++++++ i+ +v+++d+++++++Gg + + +l +sna++++++++++ +  ++pl+ +ealal+++vq++++ + +a+d+li+Kk  +   g++++v+
  EEA18699.1  35 VFKQVLEHINLDVQKFDQDITQYQGG-DPTVLLADSNAIIKTTEEGIQRIGPQPPLSVTEALALVGPVQGVNKLIMKAVDHLIEKKGPLVGGGYGPQVK 132
                 67899********************5.79********************************************************************** PP

                 HHHHHHHHHHHHHHHHHH CS
        HsbA 102 ssLqdlkaasdaLsdalv 119
                 +sL+++  a+++Ls+ + 
  EEA18699.1 133 DSLERQAHAASQLSELVS 150
                 **************9775 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.064
                 HHHHHHHHH--SH...HHHHHHHHHHHHHHHH CS
        HsbA  16 taldtavnafnGg.asalpilsasnalvsaik 46 
                 +al++ ++af+ +  +a++++  +++++++i 
  EEA18699.1 170 KALQKGIQAFSISaRQATKVKREATKVQRDIS 201
                 67888889996666789999999999998885 PP

  == domain 3  score: 76.1 bits;  conditional E-value: 8.3e-25
                 HHHHHHHHHHHHHHHHHHHHHHH--SH..HHHHHHHHHHHHHHHHHHHHHHHTS----HHHHHHHHHHHHHCHHHHHHHHHHHHHTHHHHHHHT-HHHH CS
        HsbA   2 atvisdittistavtaldtavnafnGgasalpilsasnalvsaikkattdaqasapltdeealalaqavqtLepdvkaaldaliaKkpafdkagltslv 100
                 ++++++i +is av++++ ++  +   ++a  +l + n l++a+ ++ +  q+ +pl+  ealal+++vq+L +++  a+++li+Kk+ + +ag+++ v
  EEA18699.1 201 SAFQKVIRDISLAVNKFNVDIERYVD-GDASHLLADGNVLIKATLDGVQSLQNEPPLSSMEALALVGPVQDLSNQILLAIQNLIDKKEPLVQAGFGGKV 298
                 6789********************55.36********************************************************************** PP

                 HHHHHHHHHHHHHHHHHH CS
        HsbA 101 lssLqdlkaasdaLsdal 118
                  ++L+++  a+++Ls+ +
  EEA18699.1 299 ENNLRQQEEAAQKLSELV 316
                 ***************876 PP

  == domain 4  score: -2.4 bits;  conditional E-value: 1.7
                 HHHHHHHHHHHHHHHHTS---- CS
        HsbA  38 snalvsaikkattdaqasaplt 59 
                 s+ + + ikk++++  +++p  
  EEA18699.1 332 SDGIAAGIKKGIDAFAGTGPAP 353
                 6677888999999999998854 PP

>> ThylakoidFormat  Thylakoid formation protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.0    0.0011         4     155     189 ..      25      59 ..       4      73 .. 0.82
   2 ?    1.2   0.0     0.071   2.5e+02     169     195 ..     185     211 ..     133     225 .. 0.77
   3 ?   -0.1   0.0      0.18   6.4e+02      78     112 ..     297     331 ..     283     348 .. 0.75

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0011
                      TTT...THHHHHHHHGGGS-S-HHHHHHHHHHHHH CS
  ThylakoidFormat 155 lvkdeekreealeklaealglskekvekDldlYrs 189
                      ++++++++ ++++++ e ++l+ +k ++D++ Y++
       EEA18699.1  25 QATKDQRDVNVFKQVLEHINLDVQKFDQDITQYQG 59 
                      44566677899**********************85 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.071
                      HGGGS-S-HHHHHHHHHHHHHHHHHHH CS
  ThylakoidFormat 169 laealglskekvekDldlYrsnlekle 195
                       a++++ +  kv++D+  +++++  ++
       EEA18699.1 185 QATKVKREATKVQRDISAFQKVIRDIS 211
                      456677777888888888887776554 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.18
                      HTT--HHHHHHHHHGGGGGTT-.BHHHHHHHHHTS CS
  ThylakoidFormat  78 aveedpeqyredaeeleelakeksaeellsllkqe 112
                       ve++  q +e a++l+el+++k   el+++ +q 
       EEA18699.1 297 KVENNLRQQEEAAQKLSELVSTKVPPELADISRQL 331
                      47888899999999*****9999999999887765 PP

>> AAA_lid_10  AAA lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.6   0.00017      0.62      28      77 ..     147     196 ..     131     202 .. 0.85
   2 ?   -0.6   0.0      0.41   1.5e+03      27      55 ..     313     341 ..     298     349 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00017
                 -----------------------HHHHHHHHHHT-TTTTHHHHHHHHHHH CS
  AAA_lid_10  28 eekkqklPenvkkvrlkisddaieiasrkvAsvsgdarrAlkiCkrAvEi 77 
                 e   +k+P+ +  +  ++sd++ +   + +   s +ar+A k+ + A+ +
  EEA18699.1 147 ELVSSKVPSPLAPISKQLSDQVAKALQKGIQAFSISARQATKVKREATKV 196
                 556789*************************************9999877 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.41
                 ------------------------HHHHH CS
  AAA_lid_10  27 eeekkqklPenvkkvrlkisddaieiasr 55 
                 +e    k+P ++  +  ++sd +   + +
  EEA18699.1 313 SELVSTKVPPELADISRQLSDGIAAGIKK 341
                 34456899999999999999988766665 PP

>> Flagellin_N  Bacterial flagellin N-terminal helical region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.6   0.00016      0.58      46     123 ..     131     211 ..     126     218 .. 0.82
   2 ?   -0.3   0.0      0.29     1e+03      75     103 ..     299     327 ..     297     343 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00016
                  HHHHHHHHHHHHHHHHH..HHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHT-TTTS-SHHHHHHHHHHHHHHHHHHHH CS
  Flagellin_N  46 isvslrsqiaglsqlvr..nnslgisrlqtaqgalselsdilqr.lkelavaasndsnsdedrqslqaelqqLtdelnria 123
                  + +sl++q+ + sql++  ++++ + ++ ++++  ++++++lq+ +++  + a + ++ + +++++q++++++ + +  i+
   EEA18699.1 131 VKDSLERQAHAASQLSElvSSKVPSPLAPISKQLSDQVAKALQKgIQAFSISARQATKVKREATKVQRDISAFQKVIRDIS 211
                  567888888888888764234445555667777889*************************************99998776 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.29
                  HHHHHHHHHHHHHHHHHHHHHT-TTTS-S CS
  Flagellin_N  75 qgalselsdilqrlkelavaasndsnsde 103
                  +++l ++++++q+l+el+  +   +  d+
   EEA18699.1 299 ENNLRQQEEAAQKLSELVSTKVPPELADI 327
                  67889999999999999876655555555 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.1      0.14   4.9e+02      86     111 ..      30      55 ..      12      59 .. 0.57
   2 ?    8.1   0.4   0.00072       2.6      64     118 ..     172     222 ..     132     226 .. 0.62
   3 ?   -0.3   0.0      0.29     1e+03      43      90 ..     268     317 ..     263     334 .. 0.65

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.14
     DUF1664  86 keevtevredlseigedvesvkeave 111
                 +++v+  ++ l++i+ dv++ ++ ++
  EEA18699.1  30 QRDVNVFKQVLEHINLDVQKFDQDIT 55 
                 44555555555555555555555444 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.00072
     DUF1664  64 Lssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeavegleskle 118
                 L++ i+        +++ ++++k+e t+v++d+s++++ ++ ++ av++++  +e
  EEA18699.1 172 LQKGIQAFS----ISARQATKVKREATKVQRDISAFQKVIRDISLAVNKFNVDIE 222
                 222222222....234455677888888888888888888888888888877766 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.29
     DUF1664  43 vesvskqleqvseslaatkrhLssr..idrvdkkldeqkeiskeikeevt 90 
                 v+++s+q+    ++l + k+ L +     +v+++l +q+e++++++e v+
  EEA18699.1 268 VQDLSNQILLAIQNLIDKKEPLVQAgfGGKVENNLRQQEEAAQKLSELVS 317
                 56677777777777777777777752235677777777777777776663 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (466 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1012  (0.0564449); expected 358.6 (0.02)
Passed bias filter:                      656  (0.0365888); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.61u 0.30s 00:00:00.90 Elapsed: 00:00:00.42
# Mc/sec: 3303.62
//
Query:       EEA18700.1  [L=790]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.1e-19   68.1   0.0    1.2e-18   67.1   0.0    1.5  1  Fungal_trans  Fungal specific transcription factor domain
    4.4e-09   36.3  10.1      1e-08   35.1  10.1    1.7  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.1   0.0   1.4e-22   1.2e-18       2     265 ..     318     603 ..     317     606 .. 0.80

  Alignments for each domain:
  == domain 1  score: 67.1 bits;  conditional E-value: 1.4e-22
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayasplll.........lailalGalfsesetkesnssltsesqefiafplraeilihedfsspss 89 
                   + ff+ +hp fpi+  ++f ++       ++ y+s+++          ++++a+ +++ + + + +++ + +e    ++f  +++    +++    +
    EEA18700.1 318 QNFFTTVHPTFPIIVPETFVRQV------NTFYTSSFVRpgrrwlailNLVFATSSRCFHHQMQPNSTVANDE--TLLYFSRAWKLGMKPNALLDHP 406
                   68******************999......66666666666666643336666666665555555555555553..3555666777777999999*** PP

  Fungal_trans  90 slwilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLP 186
                   +l+ +q   ll++++++++  + ++r++g+a+r a+ +gL+ ++++++      ++   +esr ++ww+ + l++++  ++Grp +ld +  ++pLP
    EEA18700.1 407 DLQQVQIEGLLAIFLLALGHVNRAWRICGIAIRSATAMGLNLRSESNY------VTLPSKESRYKVWWSLYTLETILGNMTGRPLNLDSDFCTTPLP 497
                   ************************************************......888889************************************* PP

  Fungal_trans 187 cddddlwesddaseetlvetk............................lsneeksrkiasflla...Lkkilskiagsllsiekqlqqrdlqsekl 252
                     ++ + e ++a+ ++ + +                             +     ++++a+++++   L +i+ +i+ +l+++e   +    +   +
    EEA18700.1 498 VPFE-EHEYNEAEVIRIMTDHktrnnllahvitrpvgempaagdvqsvrNAMDILNPNMALYFVCyvdLTRIMREIVETLYAPEIVQNSARDA---E 590
                   ****.*************988999999999999999999999999998866666666777666543338888888999888777655444444...5 PP

  Fungal_trans 253 swveeleraldnW 265
                   + +++ + +l++W
    EEA18700.1 591 AAITDANAKLEKW 603
                   6666666666666 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.1  10.1   1.2e-12     1e-08       1      38 [.      97     133 ..      97     136 .. 0.89

  Alignments for each domain:
  == domain 1  score: 35.1 bits;  conditional E-value: 1.2e-12
                 SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCC CS
     Zn_clus   1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfysessk 38 
                 haC++Cr +K+KC++++P+C++C+ l+l+C  y ++++
  EEA18700.1  97 HACESCRDQKTKCSGDRPTCQRCQDLGLTCL-YGDRKR 133
                 8*****************************9.555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (790 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       757  (0.0422221); expected 358.6 (0.02)
Passed bias filter:                      572  (0.0319036); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.26s 00:00:00.93 Elapsed: 00:00:00.43
# Mc/sec: 5495.24
//
Query:       EEA18701.1  [L=68]
Description: Ribosomal protein S28e [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      3e-31  107.2   2.3    3.4e-31  107.0   2.3    1.0  1  Ribosomal_S28e  Ribosomal protein S28e


Domain annotation for each model (and alignments):
>> Ribosomal_S28e  Ribosomal protein S28e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  107.0   2.3   1.9e-35   3.4e-31       3      64 .]       8      67 ..       6      67 .. 0.97

  Alignments for each domain:
  == domain 1  score: 107.0 bits;  conditional E-value: 1.9e-35
                    -EEEEEEEEEE---SSSSEEEEEEEE-S-SS-S-EEEEEEES---TT-EEEES--S--TT-- CS
  Ribosomal_S28e  3 aklAeVikvlgrtGsrGevtqVrvellegkdkgriiiRnVkGPvreGDiLtLlEterEArrL 64
                    +kl +V++vlgrtGsrG+vtqVrve+++++   r+iiRnVkGPvre+DiL+LlE+erEArrL
      EEA18701.1  8 VKLVKVTRVLGRTGSRGGVTQVRVEFMDDQ--TRSIIRNVKGPVREDDILCLLESEREARRL 67
                    78889************************8..*****************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (68 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       250  (0.0139439); expected 358.6 (0.02)
Passed bias filter:                      212  (0.0118244); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.36u 0.25s 00:00:00.61 Elapsed: 00:00:00.41
# Mc/sec: 502.70
//
Query:       EEA18702.1  [L=279]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
      0.014   15.2   0.3      0.033   14.0   0.3    1.6  1  TusA           Sulfurtransferase TusA
        2.2    7.7  11.9       0.64    9.4   7.4    2.1  2  CAP_N          Adenylate cyclase associated (CAP) N terminal


Domain annotation for each model (and alignments):
>> TusA  Sulfurtransferase TusA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.3   3.6e-06     0.033       6      41 ..     136     171 ..     135     174 .. 0.94

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 3.6e-06
                 TT-STTCCHHHHHHHHCCCGCT-EEEEEESSCHHHH CS
        TusA   6 rGlvCPePllklkkalekleegevlevladdpaate 41 
                 +Gl+CP+P+  ++ + ++  +  ++ v ++ p+a e
  EEA18702.1 136 TGLACPLPVTTTHTETKTTTATVTVTVAVTAPGAPE 171
                 69******************************9976 PP

>> CAP_N  Adenylate cyclase associated (CAP) N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.1     0.049   4.4e+02     250     260 ..      38      58 ..      23      82 .. 0.51
   2 ?    9.4   7.4   7.1e-05      0.64     236     269 ..     168     201 ..     144     239 .. 0.53

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.049
                 .XXXX..........XXXX.. CS
       CAP_N 250 PpPpP..........ppasvf 260
                 P PpP          ppas++
  EEA18702.1  38 PHPPPqtstltttsmPPASTT 58 
                 233332233333333333333 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 7.1e-05
                 SC--XXXXXXX.....XXXXXXXX.....XXXXXX CS
       CAP_N 236 aaaasaaaagg.pppPpPpPppasvfeeesaaasa 269
                  a+++++++ + + pPpPpPpp + +++++  +++
  EEA18702.1 168 GAPETTTTKPAvAIPPPPPPPPVESTSTST-LTHT 201
                 112222222222334444444443332222.2222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (279 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1087  (0.060628); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                        21  (0.00117129); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.75u 0.33s 00:00:01.08 Elapsed: 00:00:00.47
# Mc/sec: 1785.62
//
Query:       EEA18703.1  [L=803]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.9e-34  117.3  25.8    3.7e-19   69.3   1.5    5.3  5  HsbA             Hydrophobic surface binding protein A
    0.00062   20.1   1.6        1.5    9.1   0.0    3.2  2  Senescence       Senescence-associated protein
  ------ inclusion threshold ------
       0.05   13.3   0.3       0.36   10.5   0.1    2.1  2  ThylakoidFormat  Thylakoid formation protein
       0.11   12.0   0.2         17    5.0   0.0    2.5  2  POTRA_3          POTRA domain
       0.13   12.5   0.2         10    6.4   0.3    2.6  2  FliJ             Flagellar FliJ protein
       0.18   12.1   0.7         31    4.9   0.0    2.8  3  DUF5082          Domain of unknown function (DUF5082)


Domain annotation for each model (and alignments):
>> HsbA  Hydrophobic surface binding protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0      0.73   2.2e+03      18      46 ..      40      70 ..      30      74 .. 0.73
   2 !   69.3   1.5   1.2e-22   3.7e-19       4     118 ..      72     185 ..      69     187 .. 0.97
   3 ?    0.5   0.6      0.26   7.9e+02      39      69 ..     202     232 ..     198     247 .. 0.59
   4 !   59.3   1.7   1.6e-19   4.8e-16       9     117 ..     437     546 ..     423     549 .. 0.84
   5 ?    0.9   0.7      0.19   5.8e+02      31      57 ..     563     589 ..     559     596 .. 0.76

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.73
                HHHHHHH--S.H...HHHHHHHHHHHHHHHH CS
        HsbA 18 ldtavnafnG.g.asalpilsasnalvsaik 46
                l++  naf+  +  +a++++  +++++++i+
  EEA18703.1 40 LNKIGNAFSHtSiPQATKVKRETTKVQRDIR 70
                4444456655767889999999999999986 PP

  == domain 2  score: 69.3 bits;  conditional E-value: 1.2e-22
                 HHHHHHHHHHHHHHHHHHHHH--SH..HHHHHHHHHHHHHHHHHHHHHHHTS----HHHHHHHHHHHHHCHHHHHHHHHHHHHTHHHHHHHT-HHHHHH CS
        HsbA   4 visdittistavtaldtavnafnGgasalpilsasnalvsaikkattdaqasapltdeealalaqavqtLepdvkaaldaliaKkpafdkagltslvls 102
                 ++s ++ +++ v++l+t++n+++Gg +a  + ++ +++ +++++a   + +++pl + e  +l++ vq++++++ a+ +a+i+Kk+ + ++g+++ + +
  EEA18703.1  72 YQSYLSKLDQGVQQLNTDINNYQGG-DAGVLITDIDTILTTTNEASFYVGTQSPLMPREVFQLVSLVQQFKTHILATAQAFISKKDPLIASGFGPRIVA 169
                 5778999*****************5.79*********************************************************************** PP

                 HHHHHHHHHHHHHHHH CS
        HsbA 103 sLqdlkaasdaLsdal 118
                  L+++++a+++L++a+
  EEA18703.1 170 ILKKQQDATKTLGAAM 185
                 **************97 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.26
                 HHHHHHHHHHHHHHHTS----HHHHHHHHHH CS
        HsbA  39 nalvsaikkattdaqasapltdeealalaqa 69 
                 +++v+ai+k +++ + +++ t + + +  ++
  EEA18703.1 202 SEIVQAIQKVIDALSPASTPTSASSSTASTT 232
                 4555555555555555555555544444443 PP

  == domain 4  score: 59.3 bits;  conditional E-value: 1.6e-19
                 HHHHHHHH..HHHHHHHH--SH..HHHHHHHHHHHHHHHHHHHHHHHTS----HHHHHHHHHHHHHCHHHHHHHHHHHHHTHHHHHHHT-HHHHHHHHH CS
        HsbA   9 ttistavt..aldtavnafnGgasalpilsasnalvsaikkattdaqasapltdeealalaqavqtLepdvkaaldaliaKkpafdkagltslvlssLq 105
                 ++++t+++  +ldt++n+++G ++a  + ++ +++ +++++a     ++ plt+ ea +l+++vq+++  + a+ +a+i+Kk+ + ++g+++ +  +L+
  EEA18703.1 437 QQLNTDINnyQLDTDINNYQG-GDAGVLITDIDTILTTTNEASFYLGTQLPLTLREAFQLVGPVQQFKIYILATAQAFISKKDPLIASGFGPRIVERLK 534
                 233333321135555555566.58*************************************************************************** PP

                 HHHHHHHHHHHH CS
        HsbA 106 dlkaasdaLsda 117
                 ++++a+++L+  
  EEA18703.1 535 KQQDATNTLGGV 546
                 *********975 PP

  == domain 5  score: 0.9 bits;  conditional E-value: 0.19
                 HHHHHHHHHHHHHHHHHHHHHHHTS-- CS
        HsbA  31 alpilsasnalvsaikkattdaqasap 57 
                 a +i +a +++++a+  att ++as++
  EEA18703.1 563 ASEIVQAIQKVIDALSPATTPTSASSS 589
                 567888889999999888887777665 PP

>> Senescence  Senescence-associated protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.5   0.3   0.00078       2.3     102     145 ..     189     232 ..     140     237 .. 0.75
   2 !    9.1   0.0   0.00051       1.5      84     145 ..     530     594 ..     513     597 .. 0.73

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00078
  Senescence 102 gksekktaagevlnasldafstvldgleeaakqllsatsdattk 145
                   s+  + ++++++++++a+ +v+d+l  a+  +  ++s+a+t+
  EEA18703.1 189 VPSQYADLPRQFASEIVQAIQKVIDALSPASTPTSASSSTASTT 232
                 33567899*******************98887776666666665 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.00051
  Senescence  84 aksvkkkgtkss.....eeeskpgksekktaagevlnasldafstvldgleeaakqllsatsdattk 145
                 ++++kk++ + +     + ++ p  ++  + ++++++++++a+ +v+d+l  a+  +  ++s+a+t+
  EEA18703.1 530 VERLKKQQDATNtlggvMFNKVP--PQYADLPRQFASEIVQAIQKVIDALSPATTPTSASSSTASTT 594
                 55555554443345544333333..468899***********************9998888888876 PP

>> ThylakoidFormat  Thylakoid formation protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0      0.12   3.6e+02     176     199 ..      25      48 ..      15      61 .. 0.76
   2 ?   10.5   0.1   0.00012      0.36     171     199 ..      56      84 ..      50      93 .. 0.83

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.12
                      -HHHHHHHHHHHHHHHHHHHHHHH CS
  ThylakoidFormat 176 skekvekDldlYrsnlekleqake 199
                      +  k ++D+++++++l+k+ +a +
       EEA18703.1  25 HATKDQRDINVFKQVLNKIGNAFS 48 
                      567889************988755 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00012
                      GGS-S-HHHHHHHHHHHHHHHHHHHHHHH CS
  ThylakoidFormat 171 ealglskekvekDldlYrsnlekleqake 199
                      ++++ ++ kv++D+ +Y+s l+kl+q  +
       EEA18703.1  56 TKVKRETTKVQRDIRIYQSYLSKLDQGVQ 84 
                      57788999*****************9654 PP

>> POTRA_3  POTRA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.2    0.0094        28      32      43 ..      76      87 ..      75      92 .. 0.92
   2 ?    5.0   0.0    0.0055        17      32      44 ..     429     441 ..     411     452 .. 0.90

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.0094
                HHHHHHHHHHHT CS
     POTRA_3 32 LrdiEQGleqln 43
                L++++QG+ qln
  EEA18703.1 76 LSKLDQGVQQLN 87
                789********9 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.0055
                 HHHHHHHHHHHTS CS
     POTRA_3  32 LrdiEQGleqlnR 44 
                 L++++QG+ qln 
  EEA18703.1 429 LSKLDQGVQQLNT 441
                 899********95 PP

>> FliJ  Flagellar FliJ protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.3    0.0034        10      45      70 ..      67      92 ..      27      95 .. 0.77
   2 ?    3.0   0.0     0.037   1.1e+02      45      72 ..     420     447 ..     408     454 .. 0.81

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0034
        FliJ 45 aelrnyqafisaldeaiaqqkqelaq 70
                 ++r+yq+++s+ld+ ++q+  ++++
  EEA18703.1 67 RDIRIYQSYLSKLDQGVQQLNTDINN 92
                579****************9998876 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.037
        FliJ  45 aelrnyqafisaldeaiaqqkqelaqae 72 
                   l  yq ++s+ld+ ++q+  ++++ +
  EEA18703.1 420 PSLSPYQYYLSKLDQGVQQLNTDINNYQ 447
                 56778***************99998876 PP

>> DUF5082  Domain of unknown function (DUF5082)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.1     0.012        36      79     101 ..      72      94 ..      25     106 .. 0.85
   2 ?   -3.7   0.0       4.7   1.4e+04      19      44 ..     205     230 ..     200     234 .. 0.63
   3 ?    4.9   0.0      0.01        31      78     103 ..     424     449 ..     420     458 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.012
     DUF5082  79 yqtyvdkldelidaieeEIerLe 101
                 yq y +kld+ +++++++I++++
  EEA18703.1  72 YQSYLSKLDQGVQQLNTDINNYQ 94 
                 88888899999999999998887 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 4.7
     DUF5082  19 iaaleekIerLkeaktklsdekeslk 44 
                 ++a+++ I  L  a+t  s+ +++++
  EEA18703.1 205 VQAIQKVIDALSPASTPTSASSSTAS 230
                 45666777777777766666666655 PP

  == domain 3  score: 4.9 bits;  conditional E-value: 0.01
     DUF5082  78 syqtyvdkldelidaieeEIerLenq 103
                  yq y +kld+ +++++++I++++ +
  EEA18703.1 424 PYQYYLSKLDQGVQQLNTDINNYQLD 449
                 6999*****************98854 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (803 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1049  (0.0585086); expected 358.6 (0.02)
Passed bias filter:                      585  (0.0326287); expected 358.6 (0.02)
Passed Vit filter:                       159  (0.00886831); expected 17.9 (0.001)
Passed Fwd filter:                        54  (0.00301188); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.70u 0.38s 00:00:02.08 Elapsed: 00:00:00.60
# Mc/sec: 4019.49
//
Query:       EEA18704.1  [L=632]
Description: hypothetical protein PMAA_009870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
       0.75    9.7   0.0       0.75    9.7   0.0    2.8  3  F-box      F-box domain


Domain annotation for each model (and alignments):
>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.0   4.2e-05      0.75       3      32 ..     264     293 ..     262     294 .. 0.88
   2 ?   -1.5   1.8      0.14   2.5e+03      29      44 ..     331     346 ..     330     350 .. 0.66
   3 ?   -2.9   0.6      0.38   6.9e+03      25      36 ..     523     530 ..     519     536 .. 0.52

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 4.2e-05
                 HHHS-HHHHHHHHHTS-HHHHHHHCTT-HH CS
       F-box   3 lsrLPsevlrhILerLplsdllalrrVSkg 32 
                 +  LP ++ ++I+ +L+++d  +++++ k+
  EEA18704.1 264 FVKLPRDLALEIMDHLGPVDKASFALTTKS 293
                 678*****************9999998765 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.14
                 T-HHHHHHHTTHHHHH CS
       F-box  29 VSkgwrilidsdrlwc 44 
                 ++++wr l +  + ++
  EEA18704.1 331 TCWRWRLLERLENEHW 346
                 8*****7655555555 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 0.38
                 HHCTT-HHHHHH CS
       F-box  25 alrrVSkgwril 36 
                  + r+++    +
  EEA18704.1 523 TCKRCCT----Y 530
                 3444444....3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (632 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2426  (0.135312); expected 358.6 (0.02)
Passed bias filter:                      517  (0.028836); expected 358.6 (0.02)
Passed Vit filter:                        92  (0.00513135); expected 17.9 (0.001)
Passed Fwd filter:                        23  (0.00128284); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 1.05u 0.34s 00:00:01.39 Elapsed: 00:00:00.50
# Mc/sec: 3766.01
//
Query:       EEA18705.1  [L=673]
Description: hexokinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      1e-41  143.0   0.0    1.7e-41  142.4   0.0    1.4  1  Hexokinase_1  Hexokinase
    5.7e-36  124.2   0.0      9e-36  123.5   0.0    1.3  1  Hexokinase_2  Hexokinase
  ------ inclusion threshold ------
       0.58   10.8   9.8        1.6    9.4   9.8    1.7  1  SPT6_acidic   Acidic N-terminal SPT6


Domain annotation for each model (and alignments):
>> Hexokinase_1  Hexokinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  142.4   0.0   2.8e-45   1.7e-41       9     199 .]      38     323 ..      28     323 .. 0.90

  Alignments for each domain:
  == domain 1  score: 142.4 bits;  conditional E-value: 2.8e-45
                   H---HHHHHHHHHHHHHHHHHHHS.S.STS--EE----S---S--EEEEEEEEESSSEEEEEEEEEE........SSS................... CS
  Hexokinase_1   9 felsdeklkelvdrfleemekgLakekeslkmlptyvtrlPtGkekGtylAlDlGgtnlRvllveLl........ges................... 78 
                    +l++++l++l++++ ++++++La + ++ +++pt++t+lPtGke+G+ylA+ +G   l v ++eLl          +                   
    EEA18705.1  38 TTLQEQTLYQLSYNL-SKTYSHLAAH-STEQFFPTPITHLPTGKERGRYLAVYVGLFYLHVGFIELLgcdddqpqP-Qpeqahlddlggrrskwqsr 131
                   367899*********.99******88.5569************************************666555550.05556666677777889999 PP

                   ...-EEEEEEE.EE--GGGGGSBHHHHHHHHHHHHHHHHHHH....ST..T-...............S-EEEEEEE-SSEE-SBTT--EE-S--TT- CS
  Hexokinase_1  79 ...kveitqek.ykipeelktgtaeeLFdfiakciaefleeegeekkeekee...............eelplGftFSFPveqtsldegtlirwtKgf 156
                      +v++t ek ++i+e+lk ++  e+F +i+ ciae++ ++  ++++++++               +el  G++F+FP+ q+slde++l++++Kgf
    EEA18705.1 132 rwfTVRRTLEKaWPIEERLKLENPVEFFGWIGACIAEVVGDSLRNEQASNNSdgsnregygygdgeeRELVAGISFCFPIVQKSLDEAVLLPTGKGF 228
                   9**************************************8888887666655888999********99***************************** PP

                   --TT-TTSBHHHHHHHHHHHTT.....................................................-.SEEEEEEE-HHHHHHHHHHH CS
  Hexokinase_1 157 aikdvegkdvvqllqealerkg.....................................................l.pvkvvalvNDTvgtllslaY 199
                   ++ d    +++q+l +++e ++                                                     l ++k++a++NDTv+t++slaY
    EEA18705.1 229 KL-DSDL-NLRQALLDGYECHKrpqsplpfrheeeeeeedgeektnpwdefvksdtqdeheegegrtkkrrkhfsLpKLKIAAMTNDTVATFASLAY 323
                   **.5555.9*****************************************************************9745******************9 PP

>> Hexokinase_2  Hexokinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.5   0.0   1.5e-39     9e-36       2     238 ..     337     655 ..     336     657 .. 0.79

  Alignments for each domain:
  == domain 1  score: 123.5 bits;  conditional E-value: 1.5e-39
                   EEEEESSSEEEEEEEEGGG-GGGTTTS...........................-TTSEEEEE--GGGTTT.T-S.S-..--HHHHHHHHHSSSTTS CS
  Hexokinase_2   2 iGlIlGtGtNacyleklsnieklegkk...........................eksgemviNtEwgafgd.egk.lpllrtkyDkeldeespnpge 69 
                   +Gl +G G+Na++ +k+s+++  +  +                           e ++e ++ tEw  + + +   + +++tk+Dk+l+++s+ pg+
    EEA18705.1 337 MGLMVGAGSNATVPMKVSDLHPSK--TefftqpqhyhidhqgqnsssaeketetEIETETLVSTEWTLLLSsQPLlDMNILTKWDKILERQSKPPGF 431
                   9********************444..44699999999999999998888777666666679******998856666779****************** PP

                   -HHHHCCSHHHHHHHHHHHHHHHHC.T.SSSC......CCCSTTSS-THHH................HHHHC--......BTT-HHHHHHHHHCCS. CS
  Hexokinase_2  70 qlfEkmiSGmYLGelvrlvlldlieek.llfkgkse..klktpysldtefl................seieede......sedleevrevleellg. 140
                   q++E++++G+Y+Gelvrl++ld++ +   + ++     +l + ++l+t+fl                s            +e+ e + + l++ l+ 
    EEA18705.1 432 QPMEYIVGGRYMGELVRLIVLDYFTNVlRIPTDV-LpwRLLETGGLTTDFLslnvafsssspssssaS-----GisawdkHEEDEALAKELNQRLSs 522
                   ************************8542333333.236899999999999955554444444443331.....043322322222222223332223 PP

                   ...---.-HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH-..................................SSEEEEEESHHHHHSTTHHHHH CS
  Hexokinase_2 141 ...lesvteedleivrevceavsrRaarlvAagiaallkklgk.............................eekekvtvgvdGslyekypkfrerl 205
                      ++  + e++ i+r+v+ av+ R+a+++Aa++++ll  +g+                             +  e+ +v++ G+++++yp+++e l
    EEA18705.1 523 akgWT-WNAEKAGILRTVAFAVMSRSAAVIAAATVGLLACTGEiqlkdpangddiatttnpshisdnrrtwnHGPEELVVAYCGGVIQNYPRYKENL 618
                   33243.399*******************************999999************999999988888875556777****************** PP

                   HHHHHHH.HT--S....-SEEEEE---TTTHHHHHHH CS
  Hexokinase_2 206 qealrel.lgeepe...kkvklklaedGsgvGAAlia 238
                   q+ +++l l+  p+   k++ l+ + dG ++G +++a
    EEA18705.1 619 QRHIDRLlLHGGPQqggKSILLREVSDGGIIGVGVLA 655
                   *******7444444678***************99987 PP

>> SPT6_acidic  Acidic N-terminal SPT6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   9.8   0.00026       1.6       2      44 ..     259     298 ..     258     306 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00026
  SPT6_acidic   2 ssEEedddeeeerkvregFIvdddeeeeeeeeseeeeekkrrk 44 
                  ++EEe++d ee+ +  ++F+  d  +e+ee e    ++kkrrk
   EEA18705.1 259 EEEEEEEDGEEKTNPWDEFVKSDTQDEHEEGEG---RTKKRRK 298
                  688899999999999*****9997665554432...2333433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (673 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       822  (0.0458475); expected 358.6 (0.02)
Passed bias filter:                      586  (0.0326845); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.43
# Mc/sec: 4694.76
//
Query:       EEA18706.1  [L=221]
Description: hypothetical protein PMAA_009890 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (221 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       561  (0.0312901); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.46
# Mc/sec: 1439.49
//
Query:       EEA18707.1  [L=1510]
Description: ABC transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.5e-80  268.8  56.5      2e-45  154.8  24.2    2.8  3  ABC2_membrane    ABC-2 type transporter
    1.8e-36  125.7   0.0    5.3e-17   62.6   0.0    2.4  2  ABC_tran         ABC transporter
    8.6e-31  105.7  14.5    5.5e-29   99.9   0.0    3.6  3  PDR_CDR          CDR ABC transporter
    2.9e-17   63.0   0.0    7.2e-17   61.8   0.0    1.7  1  ABC_trans_N      ABC-transporter N-terminal
      2e-07   31.5   0.2    0.00023   21.6   0.1    2.7  2  AAA_16           AAA ATPase domain
    4.1e-06   26.8   0.2    0.00034   20.6   0.0    2.3  2  RsgA_GTPase      RsgA GTPase
    4.1e-05   23.2   0.4    0.00053   19.6   0.0    2.5  3  AAA_25           AAA domain
    6.4e-05   22.9   0.1        1.5    8.5   0.1    3.5  3  AAA_21           AAA domain, putative AbiEii toxin, Type IV T
    0.00063   19.5   0.3        0.2   11.4   0.1    2.3  2  AAA_30           AAA domain
    0.00099   19.3   0.1       0.12   12.6   0.0    2.6  2  AAA_33           AAA domain
     0.0013   18.4   0.4       0.42   10.2   0.1    2.3  2  cobW             CobW/HypB/UreG, nucleotide-binding domain
     0.0016   18.2   1.3      0.027   14.2   0.2    2.5  2  AAA_29           P-loop containing region of AAA domain
     0.0023   18.5   0.1       0.17   12.4   0.0    2.5  2  AAA_18           AAA domain
     0.0024   18.2   0.2        1.1    9.5   0.0    2.8  2  AAA_22           AAA domain
     0.0063   16.5   3.0          4    7.3   0.2    3.3  3  NACHT            NACHT domain
  ------ inclusion threshold ------
       0.01   16.1   0.0      0.086   13.1   0.0    2.3  2  DUF4209          Domain of unknown function (DUF4209)
      0.012   15.0   0.0        1.7    8.0   0.0    3.2  3  SMC_N            RecF/RecN/SMC N terminal domain
      0.019   15.4   0.2        3.6    8.0   0.0    2.6  2  AAA              ATPase family associated with various cellul
      0.022   15.2   0.2        1.9    8.9   0.0    2.6  2  AAA_17           AAA domain
      0.024   15.0   0.5        1.9    8.8   0.1    3.0  3  AAA_19           AAA domain
      0.031   14.1   0.1        5.7    6.7   0.0    2.4  2  dNK              Deoxynucleoside kinase
      0.038   14.3   0.1        1.8    8.8   0.0    2.4  2  AAA_28           AAA domain
      0.083   12.6   0.2         17    5.1   0.1    3.2  3  RuvB_N           Holliday junction DNA helicase RuvB P-loop d
      0.087   12.5   0.0        7.2    6.3   0.0    2.4  2  Viral_helicase1  Viral (Superfamily 1) RNA helicase
       0.12   12.1   0.1        2.7    7.7   0.0    2.5  2  IstB_IS21        IstB-like ATP binding protein
       0.16   11.2   0.2         10    5.3   0.0    2.2  2  Zeta_toxin       Zeta toxin
       0.27   10.3  39.6       0.02   14.0  21.5    2.5  2  ABC2_membrane_3  ABC-2 family transporter protein
       0.28   11.1   0.5         24    4.8   0.0    2.7  3  NTPase_1         NTPase


Domain annotation for each model (and alignments):
>> ABC2_membrane  ABC-2 type transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.2  15.8   8.6e-40   5.5e-37       2     210 .]     499     708 ..     498     708 .. 0.98
   2 !  154.8  24.2   3.1e-48     2e-45       2     208 ..    1186    1401 ..    1185    1403 .. 0.97
   3 ?   -2.6   1.3       4.7     3e+03       8      37 ..    1467    1496 ..    1462    1499 .. 0.67

  Alignments for each domain:
  == domain 1  score: 127.2 bits;  conditional E-value: 8.6e-40
  ABC2_membrane   2 qikallkreflqrwrdpslgllwrliqplllalvfgtvfgnlg.nsedglnrpgllffsvlflafsaltsvapvferergvlerelvsplyslsay 96 
                    qi +++ r f++ ++d sl+ l+ li  ++lal++ +vf++lg ++++++ r  llf +vl  +fs++ ++ ++   +r+++e++ ++ +y++++ 
     EEA18707.1 499 QIALCTHRGFQRLKGDASLT-LSGLIGNFILALIVASVFYDLGeDTASFYGRGALLFYAVLLSGFSSALEI-LTLYAQRPIVEKQARYAFYHPFTE 592
                    899*****************.**********************8899999*********************.************************ PP

  ABC2_membrane  97 vlakvlvelpvsllqalifllivyflvgldls..rfflflllllltalaasslgllisalapsfedasqlaslvllpllllsGffipidsmpkwlq 190
                    ++a++l++ p+ ++ ++ f +  yf+++l+++  +++ f+l+ ++t+ ++s l++ ++a ++s+ +a + a +++l +++++Gf+ip++ m +w +
     EEA18707.1 593 AIASMLCDSPYKIINSFTFNIPLYFMTNLRRTadAWWTFWLFSVVTTYTMSMLFRTLAATSRSLSQALVPAAVLILGMVIYTGFVIPTKYMLGWSR 688
                    ********************************9888*******************************************************55*** PP

  ABC2_membrane 191 wiaylnPltyavealrsnlf 210
                    w+ y+nP++y +e++++n+f
     EEA18707.1 689 WMNYINPIAYSFESFLVNEF 708
                    *****************997 PP

  == domain 2  score: 154.8 bits;  conditional E-value: 3.1e-48
  ABC2_membrane    2 qikallkreflqrwrdpslgllwrliqplllalvfgtvfgnlgnsedglnrpgllffsvlflafsaltsvapvferergvl.erelvsplysls 94  
                     q++  +kr f q+ r+p ++ +++l+  +l al +g+ f++++ns +gl++++  +f++++++ +++++++p+f+++r ++ +re+++++ys+ 
     EEA18707.1 1186 QLWETMKRVFSQYNRTPIYI-YSKLALSVLSALYVGFSFFHAKNSIQGLQNQMYSVFMLMTVFGNLCQQIMPLFVTQRAIYeVRERPAKTYSWQ 1278
                     88999************999.****************************999999999999999****************************** PP

  ABC2_membrane   95 ayvlakvlvelpvsllqalifllivyflvgldls.........rfflflllllltalaasslgllisalapsfedasqlaslvllpllllsGff 179 
                     a+++++++velp+++l+a+++++++y+++g++ +         r++l++l++++++l++s++++li a  +++e+a+++++l+++++l+++G++
     EEA18707.1 1279 AFMISNIFVELPWNTLMAVLMFVCWYYPIGMYNNakptdsvteRGGLMFLFVWVFLLLTSTFAHLIVAGIETAETAGNIVTLLFSLCLIFCGVL 1372
                     ***********************************9999999888************************************************* PP

  ABC2_membrane  180 ipidsmpkwlqwiaylnPltyavealrsn 208 
                      ++++mp++++++++++Plty+v++++s+
     EEA18707.1 1373 ATPQAMPRFWIFMYRVSPLTYLVQGMLST 1401
                     *************************9875 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 4.7
  ABC2_membrane    8 kreflqrwrdpslgllwrliqplllalvfg 37  
                     +  f q+wr+  l+ ++ ++++   +l+++
     EEA18707.1 1467 NTYFSQAWRNFGLIWVFIIFNIAGATLIYW 1496
                     556788888888886666666666666665 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.8   0.0   2.9e-19   1.9e-16       7     136 ..     178     332 ..     172     333 .. 0.88
   2 !   62.6   0.0   8.2e-20   5.3e-17       1     137 []     884    1035 ..     884    1035 .. 0.91

  Alignments for each domain:
  == domain 1  score: 60.8 bits;  conditional E-value: 2.9e-19
                 EEETTSEEEEEESTTSSHHHHHHHHTTSS--....SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.....................H CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....................x RF
    ABC_tran   7 klkegekvaivGenGaGKStLlkllagllkp....teGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren.....................e 80 
                  ++ ge+++++G+ G+G++tLlk++ag+++     +   ++++g ++ke  ++ ++ e  +  +++ +fp+ltv+++                     +
  EEA18707.1 178 LVRSGEMLVVLGRPGSGCTTLLKTIAGEMNGinmsEDAVVNYQGVPVKE-MHNNFKGEAIYTAETDVHFPQLTVGDTlkfaalaksprnrfegvtrdqH 275
                 5889************************998777444445777999998.8999999999999999******************999999999876544 PP

                 HHTCHHHHHHHSTTGGTTCBGESTTS.GGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  81 sdeeiekalsklglkelkdtvvkssp.ssLSgGqkqrvalarallkkpkllllDEpt 136
                 ++   + +++ lgl+++ +t+v+++  + +SgG+++rv++a+a l++++l ++D+ t
  EEA18707.1 276 ATHMRDVIMAMLGLSHTINTRVGNDFvRGVSGGERKRVSIAEAALSEAPLQCWDNST 332
                 44448999**************99999***************************987 PP

  == domain 2  score: 62.6 bits;  conditional E-value: 8.2e-20
                  EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--..SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH................ CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................ RF
    ABC_tran    1 lknvslklkegekvaivGenGaGKStLlkllagllkp..teGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren................ 79  
                  l++v+  +k+g+++a++G +GaGK+tLl +la  ++     Ge+l+dg+  ++    s++++ g+++q++ + p++tvre                 
  EEA18707.1  884 LDHVDGWVKPGTCTALMGVSGAGKTTLLDVLATRVTMgvVTGEMLVDGRARDQ----SFQRKTGYVQQQDVHLPTSTVREAlqfsallrqpghlsrk 976 
                  67788889**************************9987788898899887776....**********************************988655 PP

                  HHHTCHHHHHHHSTTGGTTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEE.EESTTT CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxx RF
    ABC_tran   80 esdeeiekalsklglkelkdtvvksspssLSgGqkqrvalarallkkpklll.lDEpta 137 
                  e+ + ++++++ l+++  +d vv+  ++ L   q++r+ +   l+ +p+lll lDEpt+
  EEA18707.1  977 EKLNYVDEVIKLLDMEAYADAVVGVPGEGLNVEQRKRLTIGVELAARPQLLLfLDEPTS 1035
                  55555********************************************87649***96 PP

>> PDR_CDR  CDR ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.9   0.0   8.6e-32   5.5e-29       1      90 [.     719     808 ..     719     810 .. 0.99
   2 ?   -1.8   0.2       4.5   2.9e+03      51      71 ..    1324    1344 ..    1316    1354 .. 0.77
   3 !   14.5   0.8   3.8e-05     0.024      32      67 ..    1460    1494 ..    1455    1505 .. 0.81

  Alignments for each domain:
  == domain 1  score: 99.9 bits;  conditional E-value: 8.6e-32
     PDR_CDR   1 vPsgpgyenvseenrvCavvGavpGqeyVsGddYlelsfgyssshlwrnfgiliaflifflalyllatelisaekskgevlvfkrgkapk 90 
                 vPsg  y++v  ++r+C++vGa +G+++V+G+ Yle+sf y + h wrn+gil++f++   a+yll te+is+ kskgevl+f+rg++p+
  EEA18707.1 719 VPSGGAYDSVPLQYRSCSTVGAAAGSNTVQGSVYLEESFAYVKGHEWRNLGILFVFMAGLAAAYLLSTEYISEVKSKGEVLLFRRGHKPT 808
                 8***************************************************************************************96 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 4.5
     PDR_CDR   51 giliaflifflalyllateli 71  
                  g +++f+ +fl+l+  ++ li
  EEA18707.1 1324 GLMFLFVWVFLLLTSTFAHLI 1344
                  778999999999988887776 PP

  == domain 3  score: 14.5 bits;  conditional E-value: 3.8e-05
     PDR_CDR   32 ddYlelsfgyssshlwrnfgiliaflifflalylla 67  
                  d+Yl+ + + + s+ wrnfg +++f+if +a   l+
  EEA18707.1 1460 DTYLA-AINTYFSQAWRNFGLIWVFIIFNIAGATLI 1494
                  78998.788899****************99866655 PP

>> ABC_trans_N  ABC-transporter N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.8   0.0   1.1e-19   7.2e-17       1      80 [.      62     149 ..      62     150 .. 0.77

  Alignments for each domain:
  == domain 1  score: 61.8 bits;  conditional E-value: 1.1e-19
  ABC_trans_N   1 eLartlsrqssssssssss........e..sssedeeeedse.Fdlekwlknlreridrdg..ikprklGVvFknLtVeGvgsgadyqpTvgn 80 
                  eLar+l+rqs++ +++           +  +ss ++    s+ F ++ w+k+l e++++d   ++ +++G++F+nL+V+G+gs +dyq++v+n
   EEA18707.1  62 ELARQLTRQSTRFAAK--GglqnpfviDdpESSLNPH---SPnFRARDWIKMLFELRSQDRgtFPEKQAGISFRNLSVHGFGSPTDYQKNVLN 149
                  79*****975555443..2344433321233333333...666****************888******************************9 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.0     0.011       7.1      19      48 ..     179     206 ..     164     290 .. 0.77
   2 !   21.6   0.1   3.6e-07   0.00023       8     143 ..     879    1032 ..     877    1061 .. 0.65

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.011
      AAA_16  19 vrsgrpelvllsGesGvGKsslvrellral 48 
                 vrsg  e++++ G +G+G ++l+++++ ++
  EEA18707.1 179 VRSG--EMLVVLGRPGSGCTTLLKTIAGEM 206
                 4444..89***************9998544 PP

  == domain 2  score: 21.6 bits;  conditional E-value: 3.6e-07
      AAA_16    8 eleqLlsalervrsgrpelvllsGesGvGKsslvrellralekdggif....lrgkcdql..esa..........ipysalaqalareellrqllde 88  
                  e++q+l+ ++ + +++  ++ l G sG GK++l++ l+++++   +++    + g++++   +++          +p s++ +al ++ llrq +  
  EEA18707.1  879 ETRQILDHVDGWVKPG-TCTALMGVSGAGKTTLLDVLATRVTMG-VVTgemlVDGRARDQsfQRKtgyvqqqdvhLPTSTVREALQFSALLRQPGHL 973 
                  88999*****999998.79*******************988866.3334444555555544455544555555555558899999888888888888 PP

      AAA_16   89 aesaeleawrekleeala......avpelagaeasrllellkrll.allsrderp.lvlvlDd 143 
                  +++ +l++ +e ++  l       av  ++g++ +   ++   +  +l++r   p l+l+lD+
  EEA18707.1  974 SRKEKLNYVDEVIKL-LDmeayadAVVGVPGEGLNVEQRKRLTIGvELAAR---PqLLLFLDE 1032
                  777777777775443.33466666555555554433333322222122222...227777775 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.1     0.082        53      91     123 ..     173     206 ..     144     221 .. 0.80
   2 !   20.6   0.0   5.3e-07   0.00034      74     125 ..     869     920 ..     853     951 .. 0.81

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.082
                  HHHHHHCTT.SEEEEECSTTSSHHHHHHHHCTT- CS
  RsgA_GTPase  91 eelkellkd.ktsvlvGqSGvGKStLinallpel 123
                  ++ + l+++ ++ v++G  G G +tL++++++e+
   EEA18707.1 173 RDFEGLVRSgEMLVVLGRPGSGCTTLLKTIAGEM 206
                  555556665599******************9985 PP

  == domain 2  score: 20.6 bits;  conditional E-value: 5.3e-07
                  HTTSEEEE--TTTHTTHHHHHHHCTT.SEEEEECSTTSSHHHHHHHHCTT--- CS
  RsgA_GTPase  74 algyevllvsaktkegleelkellkd.ktsvlvGqSGvGKStLinallpelel 125
                  ++ yev +++++t++ l+++  ++k   +++l+G SG+GK+tL+++l+ + ++
   EEA18707.1 869 DVCYEV-KIKSETRQILDHVDGWVKPgTCTALMGVSGAGKTTLLDVLATRVTM 920
                  454555.455677999*********9899******************998554 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0      0.64   4.1e+02      27      54 ..     176     203 ..     162     209 .. 0.89
   2 !   19.6   0.0   8.3e-07   0.00053      16      65 ..     877     925 ..     872     948 .. 0.82
   3 ?   -3.4   0.0       9.7   6.2e+03      72     109 ..     996    1033 ..     988    1047 .. 0.76

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.64
      AAA_25  27 kgllpagelallaGapgtGKttlaldla 54 
                 +gl++ ge  ++ G+pg+G ttl+  +a
  EEA18707.1 176 EGLVRSGEMLVVLGRPGSGCTTLLKTIA 203
                 79999*****************986655 PP

  == domain 2  score: 19.6 bits;  conditional E-value: 8.3e-07
      AAA_25  16 aapppprrwlvkgllpagelallaGapgtGKttlaldlalavatGkpwlg 65 
                 +++ ++  + v+g++  g+ ++l+G +g+GKttl+  la  v+ G  ++g
  EEA18707.1 877 KSETRQILDHVDGWVKPGTCTALMGVSGAGKTTLLDVLATRVTMGV-VTG 925
                 556666667899*******************************665.333 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 9.7
      AAA_25   72 gkVlyvsaEdsedelrrRlravgealrddarllvldla 109 
                   +V+ v +E+ + e r+Rl    e +++++ ll+ld +
  EEA18707.1  996 DAVVGVPGEGLNVEQRKRLTIGVELAARPQLLLFLDEP 1033
                  57899999999999999998544444678888888755 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.0      0.12        74     261     278 ..      84     105 ..      80     120 .. 0.74
   2 !    6.9   0.0    0.0076       4.8       2      26 ..     897     915 ..     896     953 .. 0.83
   3 !    8.5   0.1    0.0024       1.5     255     299 ..    1024    1066 ..    1012    1069 .. 0.78

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.12
      AAA_21 261 lliDEpEngLHP....kllrrl 278
                 ++iD+pE++L+P     + r  
  EEA18707.1  84 FVIDDPESSLNPhspnFRARDW 105
                 79**********6666444444 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0076
      AAA_21   2 nvliGpNgsGKSnLLdaldllarld 26 
                 ++l G  g+GK++LLd l      +
  EEA18707.1 897 TALMGVSGAGKTTLLDVL------A 915
                 8899*************9......3 PP

  == domain 3  score: 8.5 bits;  conditional E-value: 0.0024
      AAA_21  255 lkkgsllliDEpEngLHPkllrrllellkelsrngaQviltT.HSp 299 
                  ++   ll++DEp +gL+ +   ++l+l++ l+r  +Q il T H+p
  EEA18707.1 1024 PQ--LLLFLDEPTSGLDSQTSWSILDLIDTLTR-HGQAILCTiHQP 1066
                  33..69*************************99.666655441665 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0     0.016        10      13      39 ..     178     203 ..     173     217 .. 0.86
   2 !   11.4   0.1   0.00031       0.2      19      97 ..     895     985 ..     885    1005 .. 0.70

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.016
      AAA_30  13 lltsgdrvavltGpAGtGKttalkalr 39 
                 l+ sg+ + v+ G++G+G tt+lk+++
  EEA18707.1 178 LVRSGE-MLVVLGRPGSGCTTLLKTIA 203
                 667776.999**************986 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00031
      AAA_30  19 rvavltGpAGtGKttalkalreaweaag....grviglAptgkaAkvLa....eelgieastiakllkrlk.....grarlepg.tllivDEa 97 
                  +++l G+ G+GKtt+l +l+  ++       + v g A  +   ++ +    +++ +++st+ + l+  +     g  +l+++ +l  vDE+
  EEA18707.1 895 TCTALMGVSGAGKTTLLDVLATRVTMGVvtgeMLVDGRARDQSFQRKTGyvqqQDVHLPTSTVREALQFSAllrqpG--HLSRKeKLNYVDEV 985
                 57899***************888887643445333344444444433333333677789999999997777998642..45555599999996 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.084        54       2      34 ..     185     217 ..     184     296 .. 0.82
   2 !   12.6   0.0   0.00018      0.12       4      78 ..     899     970 ..     897    1007 .. 0.70

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.084
      AAA_33   2 vllvGlpGsGKstlaerllkklgavllssdtlr 34 
                 +++ G pGsG +tl++ ++ +  ++  s+d++ 
  EEA18707.1 185 LVVLGRPGSGCTTLLKTIAGEMNGINMSEDAVV 217
                 6889***************99999999999854 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 0.00018
      AAA_33   4 lvGlpGsGKstlaerllkklgavllssdtlrr.rlfgtdqqsktdytrvldrlyqilnelarkalsagrnvildat 78 
                 l G++G+GK+tl++ l+ + ++ +++   l + r + +  q+kt y +  d    +l  + + + +  ++++l+++
  EEA18707.1 899 LMGVSGAGKTTLLDVLATRVTMGVVTGEMLVDgRARDQSFQRKTGYVQQQDV---HL-PTSTVREALQFSALLRQP 970
                 68*****************999999999988867777777777766654322...22.444445555555555555 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.0     0.012       7.4       3      26 ..     185     208 ..     183     228 .. 0.77
   2 !   10.2   0.1   0.00065      0.42       2      37 ..     896     928 ..     895     950 .. 0.82

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.012
                 EEEEESTTCCHHHHHHHHHCT--S CS
        cobW   3 tvltGflGsGKTtLlnhllenrag 26 
                 +v+ G +GsG TtLl+++  + +g
  EEA18707.1 185 LVVLGRPGSGCTTLLKTIAGEMNG 208
                 7999*************9944444 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.00065
                 EEEEEESTTCCHHHHHHHHHCT--SS-EEEEESS-S CS
        cobW   2 vtvltGflGsGKTtLlnhllenraglklavivNefg 37 
                 +t l G  G+GKTtLl  l ++     + v+++e+ 
  EEA18707.1 896 CTALMGVSGAGKTTLLDVLATR---VTMGVVTGEML 928
                 57899***********999866...88999999986 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.1      0.26   1.7e+02      22      39 ..     181     199 ..     174     204 .. 0.83
   2 !   14.2   0.2   4.3e-05     0.027      22      44 ..     894     916 ..     884     921 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.26
      AAA_29  22 kg.atlltGpsGsGKSTll 39 
                 +g + ++ G+ GsG +Tll
  EEA18707.1 181 SGeMLVVLGRPGSGCTTLL 199
                 45588999**********8 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 4.3e-05
      AAA_29  22 kgatlltGpsGsGKSTllDAiqa 44 
                    t l+G sG+GK+TllD +++
  EEA18707.1 894 GTCTALMGVSGAGKTTLLDVLAT 916
                 44899**************8765 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0      0.15        97       2      25 ..     186     221 ..     185     245 .. 0.73
   2 !   12.4   0.0   0.00027      0.17       3      55 ..     899     949 ..     898    1028 .. 0.60

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.15
      AAA_18   2 lltGtpGvGKttlakeLskrl.gf...........g 25 
                 ++ G pG+G ttl k ++ ++ g+           g
  EEA18707.1 186 VVLGRPGSGCTTLLKTIAGEMnGInmsedavvnyqG 221
                 589**************7776444555555444444 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 0.00027
      AAA_18   3 ltGtpGvGKttlakeLskrlgfgvnlrdvakenglllevdpealdeskrlded 55 
                 l+G++G+GKttl + L+ r  +gv+ ++++ +++ ++  ++   +   + ++d
  EEA18707.1 899 LMGVSGAGKTTLLDVLATRVTMGVVTGEMLVDGRARDQSFQR--KTGYVQQQD 949
                 89**************99976666666666665555555555..333333332 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.0     0.031        20       4      26 ..     181     203 ..     179     224 .. 0.88
   2 !    9.5   0.0    0.0017       1.1       5      28 ..     894     917 ..     891     971 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.031
      AAA_22   4 tagilvvtGesGtGKTtllrrll 26 
                 +  +lvv G +G+G Ttll++++
  EEA18707.1 181 SGEMLVVLGRPGSGCTTLLKTIA 203
                 6789****************986 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.0017
      AAA_22   5 agilvvtGesGtGKTtllrrlleq 28 
                  ++++++G sG+GKTtll  l+ +
  EEA18707.1 894 GTCTALMGVSGAGKTTLLDVLATR 917
                 689**************9877665 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.2   0.0    0.0068       4.3       2      24 ..     184     206 ..     183     218 .. 0.86
   2 !    7.3   0.2    0.0062         4       4      27 ..     898     921 ..     895     929 .. 0.82
   3 ?   -0.5   0.1       1.6     1e+03      52      86 ..    1046    1080 ..    1024    1083 .. 0.84

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0068
                 CEEEEC-TTTCHHHHHHHHHHHH CS
       NACHT   2 lvilqGeaGsGKTtLlqklalaw 24 
                 ++++ G++GsG TtLl+ +a ++
  EEA18707.1 184 MLVVLGRPGSGCTTLLKTIAGEM 206
                 5899***************9776 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0062
                 EEEC-TTTCHHHHHHHHHHHHCTS CS
       NACHT   4 ilqGeaGsGKTtLlqklalawaeg 27 
                 +l G +G GKTtLl  la+    g
  EEA18707.1 898 ALMGVSGAGKTTLLDVLATRVTMG 921
                 789************999877655 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 1.6
                  .-HCHHHCCCCTS--SSS-CCHHHHCCSCCCEEEE CS
       NACHT   52 rsladllfsqlpepaapvsevwavllelperlLli 86  
                  + l+d+l+++++++  ++ +  a+l ++++rlL++
  EEA18707.1 1046 LDLIDTLTRHGQAILCTIHQPSAMLFQRFDRLLFL 1080
                  7899999999999999999999***********97 PP

>> DUF4209  Domain of unknown function (DUF4209)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   0.00014     0.086      55      85 ..     124     154 ..     120     158 .. 0.91
   2 ?   -0.3   0.0         2   1.3e+03      30      60 ..     178     211 ..     160     212 .. 0.74

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 0.00014
     DUF4209  55 prglNLRNvvwHGfiseeefsksllslllll 85 
                 ++g+ +RN+++HGf s+++++k++l  ll +
  EEA18707.1 124 QAGISFRNLSVHGFGSPTDYQKNVLNSLLEI 154
                 78999*******************9999876 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 2
     DUF4209  30 lLaseelkeil...geelalilrvllgpprglNL 60 
                 l +s e+  +l   g+  + +l+++ g+ +g+N+
  EEA18707.1 178 LVRSGEMLVVLgrpGSGCTTLLKTIAGEMNGINM 211
                 56666776677666788999*************6 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.52   3.3e+02     113     187 ..     217     351 ..     181     380 .. 0.71
   2 ?    1.3   0.0       0.3   1.9e+02      26      44 ..     896     914 ..     884     945 .. 0.86
   3 ?    8.0   0.0    0.0026       1.7     156     206 ..    1022    1072 ..    1016    1085 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.52
                 ETTEEE-HHHHHHHHHCTT-STT................................................................CS-HHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxx................................................................xxxxxxxxxxxx RF
       SMC_N 113 ingkevtkkevsellesagiske................................................................lLSgGektLval 147
                 +n + v  ke+++ ++ + i+                                                                    SgGe++ v++
  EEA18707.1 217 VNYQGVPVKEMHNNFKGEAIYTAetdvhfpqltvgdtlkfaalaksprnrfegvtrdqhathmrdvimamlglshtintrvgndfvrGVSGGERKRVSI 315
                 555555666666666666666556666666666666666666666666666666666666666666666666666677777777776789999998876 PP

                 HHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 148 aLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeks 187
                 a      + + apl + D+    LD +n  ++++ l   s
  EEA18707.1 316 A----EAALSEAPLQCWDNSTRGLDSANALEFCKNLALMS 351
                 5....55778899999999999999999888887776555 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.3
                 EEEEEESTTSSHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxx RF
       SMC_N  26 ftaivGpNGSGKsnlldAi 44 
                  ta++G  G+GK+ lld +
  EEA18707.1 896 CTALMGVSGAGKTTLLDVL 914
                 699*************965 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.0026
                  CS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC-S CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  156 vkpaplyllDeidaaLDeknvkkvaellkeksknaQfivislreemlekad 206 
                  ++p+ l +lDe  + LD +    + +l+++ + + Q i  ++++      +
  EEA18707.1 1022 ARPQLLLFLDEPTSGLDSQTSWSILDLIDTLTRHGQAILCTIHQPSAMLFQ 1072
                  689999***********************************9987665555 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   0.0    0.0057       3.6       2      45 ..     186     226 ..     185     242 .. 0.71
   2 ?    4.7   0.1      0.06        38       3      23 ..     899     919 ..     897     947 .. 0.85

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0057
                 EEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHH CS
         AAA   2 llyGppGtGKTllakavakelgvefleisgsellskyvgesekk 45 
                 ++ G pG G T+l k +a e++   +++s   ++ +y+g   k+
  EEA18707.1 186 VVLGRPGSGCTTLLKTIAGEMNG--INMSEDAVV-NYQGVPVKE 226
                 688*****************853..455554444.444444444 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.06
                 EESSTTSSHHHHHHHHHHHHT CS
         AAA   3 lyGppGtGKTllakavakelg 23 
                 l+G  G GKT+l   +a+ + 
  EEA18707.1 899 LMGVSGAGKTTLLDVLATRVT 919
                 89**************99864 PP

>> AAA_17  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0      0.14        92       1      20 [.     188     207 ..     188     213 .. 0.87
   2 ?    8.9   0.0     0.003       1.9       1      49 [.     900     948 ..     900     968 .. 0.76

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.14
                 EE-TTSSHHHHHHHHHHHHT CS
      AAA_17   1 lGgPGsGKgtqceklvekyg 20 
                 lG PGsG +t++++++ +++
  EEA18707.1 188 LGRPGSGCTTLLKTIAGEMN 207
                 699************99884 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.003
                 EE-TTSSHHHHHHHHHHHHTEEEEEHHHHHHHHHHTTTS.HSSHHHHCTS CS
      AAA_17   1 lGgPGsGKgtqceklvekygfthlsaGdllreeakrggl.akardemrkl 49 
                 +G+ G+GK+t+++ l+ ++   +++ G++l +  +r+++ +++ +++++ 
  EEA18707.1 900 MGVSGAGKTTLLDVLATRVTMGVVT-GEMLVDGRARDQSfQRKTGYVQQQ 948
                 59****************9999998.999997666665435555655544 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   0.1     0.003       1.9      10      62 ..     182     231 ..     176     295 .. 0.77
   2 ?    2.4   0.0      0.27   1.8e+02      11      32 ..     895     916 ..     890     992 .. 0.76
   3 ?   -1.4   0.0       4.3   2.7e+03      42      62 ..    1251    1271 ..    1239    1298 .. 0.84

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.003
      AAA_19  10 ekvllvtaGpGtGKTrvlkhivallvelggvkpeeillvaftgrAakelrerl 62 
                  ++l+v++ pG+G T++lk+i  +++ ++   + e ++v + g  +ke++++ 
  EEA18707.1 182 GEMLVVLGRPGSGCTTLLKTIAGEMNGIN---MSEDAVVNYQGVPVKEMHNNF 231
                 57899****************99888777...457778888888888888877 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.27
      AAA_19  11 kvllvtaGpGtGKTrvlkhiva 32 
                 ++ ++++  G GKT++l    +
  EEA18707.1 895 TCTALMGVSGAGKTTLLDVLAT 916
                 678999********98865433 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 4.3
      AAA_19   42 peeillvaftgrAakelrerl 62  
                   ++i+ + +t+rA  e+rer 
  EEA18707.1 1251 CQQIMPLFVTQRAIYEVRERP 1271
                  47999999**********986 PP

>> dNK  Deoxynucleoside kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   0.0    0.0089       5.7       2      51 ..     186     233 ..     185     264 .. 0.84
   2 ?    4.7   0.0     0.036        23       5      28 ..     901     924 ..     898     947 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0089
                 EEEESTTSSHHHHHHHHHCCST.CEEEE-HHHHCCSSSSHHHHHHHHSHHH CS
         dNK   2 vveGnIgaGKstlvklLskklg.vkvfeEpvdkwtnvqknlLekfYkdpsr 51 
                 vv G  g+G +tl+k+++ +++ +++ e+ v ++   q+  ++ +++++++
  EEA18707.1 186 VVLGRPGSGCTTLLKTIAGEMNgINMSEDAVVNY---QGVPVKEMHNNFKG 233
                 788999**********9999988***********...67888888888876 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.036
                 ESTTSSHHHHHHHHHCCSTCEEEE CS
         dNK   5 GnIgaGKstlvklLskklgvkvfe 28 
                 G  gaGK+tl+++L+ ++ + v++
  EEA18707.1 901 GVSGAGKTTLLDVLATRVTMGVVT 924
                 7789***********998866654 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0      0.18   1.1e+02       3      31 ..     186     216 ..     184     240 .. 0.84
   2 ?    8.8   0.0    0.0029       1.8       3      29 ..     898     926 ..     896     970 .. 0.71

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.18
      AAA_28   3 vitGgestGKTtlleaLaar..gypvvpEaa 31 
                 v++G +++G Ttll+ +a +  g+++ ++a+
  EEA18707.1 186 VVLGRPGSGCTTLLKTIAGEmnGINMSEDAV 216
                 899***************5446887776665 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0029
      AAA_28   3 vitGgestGKTtlleaLaar...gypvv.pE 29 
                 +++G +++GKTtll  La r   g  vv  E
  EEA18707.1 898 ALMGVSGAGKTTLLDVLATRvtmG--VVtGE 926
                 789***************997442..33333 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.1     0.026        17      36      59 ..     185     208 ..     179     245 .. 0.83
   2 ?   -0.9   0.0       1.9   1.2e+03     107     142 ..     709     744 ..     693     758 .. 0.86
   3 ?    3.0   0.0      0.12        75      37      60 ..     898     921 ..     874     935 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.026
      RuvB_N  36 vllyGpPGlGkttlakiiakelgv 59 
                 +++ G PG G ttl k ia e++ 
  EEA18707.1 185 LVVLGRPGSGCTTLLKTIAGEMNG 208
                 5788******************74 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 1.9
      RuvB_N 107 amedfrldivigkGpsarsikldlpkftlvgattra 142
                 a  df+  +++ +G +  s+ l+    + vga++ +
  EEA18707.1 709 ANRDFNCSVMVPSGGAYDSVPLQYRSCSTVGAAAGS 744
                 6689**************************998755 PP

  == domain 3  score: 3.0 bits;  conditional E-value: 0.12
      RuvB_N  37 llyGpPGlGkttlakiiakelgvk 60 
                  l+G  G Gkttl  ++a+ + + 
  EEA18707.1 898 ALMGVSGAGKTTLLDVLATRVTMG 921
                 589***************987654 PP

>> Viral_helicase1  Viral (Superfamily 1) RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0     0.063        40       2      21 ..     186     205 ..     185     232 .. 0.81
   2 ?    6.3   0.0     0.011       7.2       4      40 ..     900     935 ..     897     990 .. 0.76

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.063
  Viral_helicase1   2 vvhGvpGcGKStlirkllrt 21 
                      vv G pG+G +tl+++++ +
       EEA18707.1 186 VVLGRPGSGCTTLLKTIAGE 205
                      99***************987 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.011
  Viral_helicase1   4 hGvpGcGKStlirkllrtsliltvnrptaelltegk..p 40 
                       Gv G+GK+tl+  l+     +t+++ t e+l +g+  +
       EEA18707.1 900 MGVSGAGKTTLLDVLATR---VTMGVVTGEMLVDGRarD 935
                      59********99888877...788888888887777541 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0       0.4   2.5e+02      43      69 ..     178     204 ..     158     236 .. 0.76
   2 ?    7.7   0.0    0.0043       2.7      27      68 ..     875     915 ..     854     923 .. 0.72

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.4
   IstB_IS21  43 fiekkenivllGpsGvGKshlaialgv 69 
                  +++ e +v+lG +G G + l  +++ 
  EEA18707.1 178 LVRSGEMLVVLGRPGSGCTTLLKTIAG 204
                 5788999***********999776654 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0043
   IstB_IS21  27 arsldkrkvkeLatlsfiekkenivllGpsGvGKshlaialg 68 
                 + +++ r++ +   + +++   + +l+G sG+GK+ l   l+
  EEA18707.1 875 KIKSETRQILD-HVDGWVKPGTCTALMGVSGAGKTTLLDVLA 915
                 44444444433.3457*******************9876665 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.016        10      18      63 ..     184     233 ..     179     257 .. 0.82
   2 ?    3.4   0.1     0.062        40      21      41 ..     899     919 ..     893     928 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.016
  Zeta_toxin  18 lillgGqpGAGKselaellkdele....rqgnvvrldpDdlRelhPeyee 63 
                 ++++ G pG+G ++l++ ++ e++    +++ vv  ++  ++e+h ++++
  EEA18707.1 184 MLVVLGRPGSGCTTLLKTIAGEMNginmSEDAVVNYQGVPVKEMHNNFKG 233
                 567789*****************988877788888888888888888876 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.062
  Zeta_toxin  21 lgGqpGAGKselaellkdele 41 
                 l G +GAGK++l++ l+++++
  EEA18707.1 899 LMGVSGAGKTTLLDVLATRVT 919
                 56889*********9999873 PP

>> ABC2_membrane_3  ABC-2 family transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6  10.1      0.18   1.2e+02     241     314 ..     630     704 ..     522     784 .. 0.71
   2 ?   14.0  21.5   3.1e-05      0.02     151     340 ..    1225    1488 ..    1190    1497 .. 0.76

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.18
  ABC2_membrane_3 241 ll.llfllfglayialgyllsslfknsetaqilifivil.llsgffgglfp.ledlpsalkwifsiiPffapglgll 314
                      ++ l++++   ++++l+  l + +++    q+l+++  l l +++++g+++ ++ + ++ +w  +i+P+ + ++++l
       EEA18707.1 630 TFwLFSVVTTYTMSMLFRTLAATSRSL--SQALVPAAVLiLGMVIYTGFVIpTKYMLGWSRWMNYINPIAYSFESFL 704
                      443444444444444433334434444..4555444333247888888855488899************99999884 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 3.1e-05
  ABC2_membrane_3  151 qleeelsnvasflvg.liliilifitasfiavsi........veEkesrikelqlvsgvsplqywlskilgdflvyllqlllill.l.afgl 231 
                         +++ ++ ++++++ ++l+ ++   +++i+  +        v+E+  ++   q  +    ++ +++ + +  l+++l+++ + + + +++ 
       EEA18707.1 1225 HAKNSIQGLQNQMYSvFMLMTVFGNLCQQIMPLFvtqraiyeVRERPAKTYSWQAFM----ISNIFVELPWNTLMAVLMFVCWYYpIgMYNN 1312
                       446666777777777544444454555555543212222344555555555555555....4444555557777777777777777677776 PP

  ABC2_membrane_3  232 ...gipfg.nlglllllfllfglayialgyllsslfknsetaqilifivilllsgffgglfpledlpsalkwifsiiPffapglgllrlitg 319 
                            +++   gl++l++ +f+l+++++++l+ + + ++eta  +++++++l ++f+g+l + +++p ++    ++ P++++ +g+l+ +  
       EEA18707.1 1313 akpTDSVTeRGGLMFLFVWVFLLLTSTFAHLIVAGIETAETAGNIVTLLFSLCLIFCGVLATPQAMPRFWIFMYRVSPLTYLVQGMLSTGLS 1404
                       555333332448888999999********************99999999999*************************************844 PP

  ABC2_membrane_3  320 dplwe...............................................................illsliilalfavvyl 340 
                        + +e                                                                ++++++ ++f+++ +
       EEA18707.1 1405 GTTVEcadveyitfdpppgfstcidymggfinatggylrepdatsncqyciisstdtylaaintyfsqAWRNFGLIWVFIIFNI 1488
                       446678889999999999999999999999999999999999999999999999999999999999999999999999999855 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.0     0.037        24       3      28 ..     186     211 ..     184     237 .. 0.72
   2 ?    3.3   0.1      0.11        67       4      39 ..     899     928 ..     896     939 .. 0.75
   3 ?   -2.7   0.0       7.4   4.7e+03     117     143 ..    1048    1073 ..    1042    1077 .. 0.73

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.037
                 EEE--TTSSHHHHHHHHHHHH...GG CS
    NTPase_1   3 fiTGppGvGKtTlvkkvlellkssgv 28 
                 ++ G+pG+G tTl+k ++ +++  ++
  EEA18707.1 186 VVLGRPGSGCTTLLKTIAGEMNGINM 211
                 678**************998865554 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.11
                 EE--TTSSHHHHHHHHHHHH...GGGEEEEEEEEE- CS
    NTPase_1   4 iTGppGvGKtTlvkkvlellkssgvkvgGfyteevr 39 
                 + G +G GKtTl++ ++  +        G++t e+ 
  EEA18707.1 899 LMGVSGAGKTTLLDVLATRV------TMGVVTGEML 928
                 67999********9998888......4455555555 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 7.4
                  HHHHHHTTTSEEEEE--SS--SHHHHH CS
    NTPase_1  117 aveevLksekpvlavihrrkdlalvee 143 
                   ++++ ++++ +l +ih++ +  l ++
  EEA18707.1 1048 LIDTLTRHGQAILCTIHQP-SAMLFQR 1073
                  45666669999*******9.4556655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1510 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       751  (0.0418874); expected 358.6 (0.02)
Passed bias filter:                      477  (0.0266049); expected 358.6 (0.02)
Passed Vit filter:                        88  (0.00490825); expected 17.9 (0.001)
Passed Fwd filter:                        34  (0.00189637); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              28  [number of targets reported over threshold]
# CPU time: 1.02u 0.32s 00:00:01.34 Elapsed: 00:00:00.47
# Mc/sec: 9672.06
//
Query:       EEA18708.1  [L=189]
Description: iron-sulfur cofactor synthesis protein (Isu1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-35  122.4   0.0    1.7e-35  121.9   0.0    1.1  1  NifU_N    NifU-like N terminal domain


Domain annotation for each model (and alignments):
>> NifU_N  NifU-like N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.9   0.0   9.6e-40   1.7e-35      12     126 ..      58     167 ..      51     170 .. 0.95

  Alignments for each domain:
  == domain 1  score: 121.9 bits;  conditional E-value: 9.6e-40
                 SSSSBSS-TTSSS--EEEEEEETTTTEEEEEEEEEETTTTEEEEEEEEEESSHHHHHHHHHHHHHHTTSBHHHHCCCCHHHHHHHHTCSCSSSCHCSCH CS
      NifU_N  12 nPrnvGvleeedakvgvgevgapacGDavrLqikvdeetdriedakFktfGCgsaiAssslltelvkgktleealkitnkeiaeelgglpkeklhcsvl 110
                 n + vG+l+ ++++vg+g vgapa    +rL i+vde+t++i+ + FktfGCgsaiAsss+lt l+ gktleea ki+n++ia+el+ lp++klhcs l
  EEA18708.1  58 NLKLVGSLDRKSNDVGSGLVGAPA----IRLDIQVDEKTGKIVKSAFKTFGCGSAIASSSYLTTLLAGKTLEEAGKIQNTQIANELC-LPPVKLHCSLL 151
                 55679******************6....8**********************************************************.*********** PP

                 HHHHHHHHHHHHHHHC CS
      NifU_N 111 aedalkaavkkYkakk 126
                 aeda+kaa+k+Y++k+
  EEA18708.1 152 AEDAIKAAIKNYQSKR 167
                 *************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (189 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       417  (0.0232584); expected 358.6 (0.02)
Passed bias filter:                      333  (0.0185733); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.27s 00:00:00.67 Elapsed: 00:00:00.43
# Mc/sec: 1329.73
//
Query:       EEA18709.1  [L=333]
Description: aldo/keto reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.5e-59  199.8   0.0    6.2e-59  199.6   0.0    1.0  1  Aldo_ket_red  Aldo/keto reductase family


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  199.6   0.0   3.5e-63   6.2e-59       1     293 [.      12     313 ..      12     314 .. 0.97

  Alignments for each domain:
  == domain 1  score: 199.6 bits;  conditional E-value: 3.5e-63
                   .EEEE-SSS-ST..TS-HHHHHHHHHHHHHTT--EEE--TT-..TTTHHHHHHHHHHHH-TTTGGG-EEEEEE--SSSTTSSSS-HHHHHHHHHHHH CS
  Aldo_ket_red   1 elglGtwqlgsk.eeiskeealellrraleaGinffDtAevY..gkgqseellGealkksrkkreeviiatKvdlrdaeiksglskeniresleesl 94 
                   ++g+G++ l+s+    s +e++++++rale G +f++ +e+Y   +  s +ll  ++ k++++ ++v +++K+ ++  +  ++ s+e +r+s+e+ l
    EEA18709.1  12 PIGFGLMGLTSRsYSPSFDESVKVMKRALELGATFWNGGEFYgpPNSNSLHLLEYYFRKYPEDADKVTLSIKGCFSLVAGGPDNSPEGVRKSVENCL 108
                   79**********9999**************************65567777889999999************************************** PP

                   HHHT-.S-EEEEEE-S--TTS-.HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHHHHTTT--EEEEE-B-BTT.-HHHHTTHHHHHHHTT-EEEEB CS
  Aldo_ket_red  95 krLgt.dyvDllllHrpdpslpsieevldaleelvkeGkiraiGvSnfsveqlekakkkkkvkivavqveynll.releeegllelckkkgvpliay 189
                   + L+    + +++ +r+dp++p iee++++l+e+vkeGki +iG+S+  ++ +++a  +++++i+av+ e +l+  ++ ++g++++c+++gvp++ay
    EEA18709.1 109 SILQGrVPIHIFEPARIDPKTP-IEETIKTLAEYVKEGKIGGIGLSEAGAATIRRA--HAVHPIAAVELELSLFtPDILANGIASTCAELGVPIVAY 202
                   ****9899**************.*******************************99..****************999******************** PP

                   STTGGGTTGTTTSS---SSSCCC-------..TS-HHHHHHHHHHHHHHHH.TT--HHHHHHHHHTTS......TT-SEEEE--SSHHHHHHHHGGG CS
  Aldo_ket_red 190 splggGlltgkyqseedkedkeprkdlkrd..ertsknldaaeelselake.hgvslaqlalryalsq......pavgivipgasnieqlednldal 277
                   splg G+l+ + ++ +d ++ke r+++ r+    ++ n+  a+++++ a+   gv+ aq+a++++l+q      p + +vipg+++++++e+n    
    EEA18709.1 203 SPLGCGFLSDRFTKLSDLDEKEFRRHQPRFqpGAFEANMRVADQVRKTAQAhVGVTTAQVAIAWVLAQctkiglPEGLVVIPGCTTVARVEENSTEI 299
                   ***************************999*******************995688**************************************9999 PP

                   G----HHHHHHHHHHH CS
  Aldo_ket_red 278 elklseeevaeldell 293
                     +lse e++ ld+++
    EEA18709.1 300 --QLSEAELESLDNIV 313
                   ..***********986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (333 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       519  (0.0289475); expected 358.6 (0.02)
Passed bias filter:                      496  (0.0276647); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2365.99
//
Query:       EEA18710.1  [L=464]
Description: hypothetical protein PMAA_009930 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
       0.02   13.7   0.2      0.034   12.9   0.2    1.3  1  Fungal_trans_2  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.2   1.9e-06     0.034      28     139 ..       5     115 ..       2     145 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.9e-06
  Fungal_trans_2  28 llplalsnkallhallalsafhlqskgpkds....lereakrykslalkelqealaelsstlsrnekykdiLaaiLllcsieissgdvsdwrvhL 118
                     l+   +++ a+ h +l+++  hl  ++ + s    ++ ++++ ++++  +  +al+ l +  +       +L ++L+ c++e  +g+ +   +h+
      EEA18710.1   5 LFSSFHAEAAIQHIILSVG--HLLGTHAPTSdktwNMMQKEQQQQMVYYHYGKALNALVNSPN--PDVYIVLLSCLIFCLFEELQGNCYPAIQHI 95 
                     56667888899******99..775555555557778899999999999999999999999999..4444556666************999***** PP

  Fungal_trans_2 119 eaatsliksrggs...kassssls 139
                      a +++i ++  +   +    ++s
      EEA18710.1  96 VAGRDIILRHIQTrkpS----TRS 115
                     *******9999984331....333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (464 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       472  (0.0263261); expected 358.6 (0.02)
Passed bias filter:                      419  (0.02337); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.48
# Mc/sec: 2906.94
//
Query:       EEA18711.1  [L=114]
Description: apoptosis-inducing TAF9-like domain 1 family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    9.7e-36  122.0   0.0    1.4e-35  121.5   0.0    1.2  1  CENP-S       CENP-S protein
    7.5e-10   38.9   0.0      1e-09   38.5   0.0    1.4  1  CENP-T_C     Centromere kinetochore component CENP-T histone 
    0.00066   19.6   0.0     0.0011   18.9   0.0    1.3  1  Bromo_TP     Bromodomain associated
  ------ inclusion threshold ------
      0.013   15.9   0.0      0.021   15.2   0.0    1.4  1  Histone      Core histone H2A/H2B/H3/H4
      0.053   13.6   0.0      0.062   13.4   0.0    1.2  1  TFIID-31kDa  Transcription initiation factor IID, 31kD subuni
       0.19   12.2   0.0       0.25   11.8   0.0    1.2  1  DUF3433      Protein of unknown function (DUF3433)


Domain annotation for each model (and alignments):
>> CENP-S  CENP-S protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.5   0.0   4.6e-39   1.4e-35       1      76 []      14      89 ..      14      89 .. 0.99

  Alignments for each domain:
  == domain 1  score: 121.5 bits;  conditional E-value: 4.6e-39
      CENP-S  1 erLKaalwysvgkiveeeaaekeveatkqfiaaltelvykqlenlakDLeaFakHAkRstittdDvlLlaRrnesL 76
                er+K+alw+++gkiv+ee+++ +v+at+qfi+alte+v++q+e++++DLeaFakHA+Rsti+t+Dv+LlaRrne L
  EEA18711.1 14 ERFKSALWLAIGKIVDEETMQLGVNATPQFIGALTEMVWAQIESVSQDLEAFAKHAGRSTINTNDVMLLARRNEGL 89
                69***********************************************************************987 PP

>> CENP-T_C  Centromere kinetochore component CENP-T histone fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.5   0.0   3.4e-13     1e-09      36      82 ..      45      91 ..      22     110 .. 0.80

  Alignments for each domain:
  == domain 1  score: 38.5 bits;  conditional E-value: 3.4e-13
    CENP-T_C 36 kalekasdkffeqvgeDLeayakHagRKtidesDvilLmkrqrkvts 82
                 al+++    +e v++DLea+akHagR ti+++Dv+lL +r+  ++s
  EEA18711.1 45 GALTEMVWAQIESVSQDLEAFAKHAGRSTINTNDVMLLARRNEGLES 91
                5666666667899****************************766554 PP

>> Bromo_TP  Bromodomain associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.0   3.7e-07    0.0011      24      66 ..      39      81 ..      31      86 .. 0.92

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 3.7e-07
                E-HHHHHHHHHHHHHHHHHHHHHHHHHHTTSS-SS--HHHHHH CS
    Bromo_TP 24 aeesaLEtLteiaqkYirelgeqaksfaehagRseptlkDvvl 66
                a++  + +Lte++   i++++++ ++fa hagRs+ +  Dv+l
  EEA18711.1 39 ATPQFIGALTEMVWAQIESVSQDLEAFAKHAGRSTINTNDVML 81
                66778889*********************************95 PP

>> Histone  Core histone H2A/H2B/H3/H4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   0.0   6.9e-06     0.021      87     129 ..      42      84 ..      24      86 .. 0.85

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 6.9e-06
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHTTXSEEXHHHHHHHHH CS
     Histone  87 eavlalqealEallvelfeeAnllakhaKRvTitpkDiqlArr 129
                 + + al+e++ a ++++ ++ +  akha R+Ti+  D+ l +r
  EEA18711.1  42 QFIGALTEMVWAQIESVSQDLEAFAKHAGRSTINTNDVMLLAR 84 
                 56889********************************988766 PP

>> TFIID-31kDa  Transcription initiation factor IID, 31kD subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   2.1e-05     0.062      23      65 ..      39      81 ..      23     112 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 2.1e-05
  TFIID-31kDa 23 yeerVvlqLldfayrytssvLedAkvlaehakkkevslddvrl 65
                   ++ +  L +++   + sv +d +++a+ha++++++++dv l
   EEA18711.1 39 ATPQFIGALTEMVWAQIESVSQDLEAFAKHAGRSTINTNDVML 81
                 45778899*********************************87 PP

>> DUF3433  Protein of unknown function (DUF3433)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   8.4e-05      0.25       2      63 ..      36      97 ..      35     103 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 8.4e-05
     DUF3433  2 lvsflpalvavlisllwaaldaavrrlaPFaaLahrgataersllldyratlpflallralr 63
                +v+  p++++ l  ++wa+++   + l+ Fa  a r + + + ++l  r    + ++lra+ 
  EEA18711.1 36 GVNATPQFIGALTEMVWAQIESVSQDLEAFAKHAGRSTINTNDVMLLARRNEGLESILRAFV 97
                67889**************************9998888887777776666666668888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (114 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       705  (0.0393218); expected 358.6 (0.02)
Passed bias filter:                      356  (0.0198561); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.41u 0.27s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 793.78
//
Query:       EEA18712.1  [L=248]
Description: hypothetical protein PMAA_009950 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.066   12.9   0.2       0.38   10.4   0.0    2.1  2  SLT       Transglycosylase SLT domain


Domain annotation for each model (and alignments):
>> SLT  Transglycosylase SLT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   2.1e-05      0.38       4      42 ..     105     146 ..     102     154 .. 0.83
   2 ?   -0.6   0.2     0.054   9.8e+02      73      99 ..     187     213 ..     185     218 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 2.1e-05
                 HHHHHHHTS-HHHHHHHHHHHHTT-TT-B-...TTSEBTTTT CS
         SLT   4 ikaekkygvepsllaaiaqvESgfnpkAvs...ksgavGLmQ 42 
                  + + +  v+ ++++a++++ES +  ++ s   ++   GLmQ
  EEA18712.1 105 DAIAAETYVDHRFILAVIMQESTGCVRVPSsigSVTNPGLMQ 146
                 567788899**************987777744477799***9 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.054
                 HHHHHHHHHTTTTHHHHHHHHHHH-HH CS
         SLT  73 akyLkslykqyngslllalaAYNaGeg 99 
                 a+ L++ ++++ +  ++a+  YN+G  
  EEA18712.1 187 ANCLNEANATGAEAFYRAARIYNSGSV 213
                 57889999999999999*******975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (248 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       422  (0.0235373); expected 358.6 (0.02)
Passed bias filter:                      353  (0.0196888); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.29s 00:00:00.78 Elapsed: 00:00:00.47
# Mc/sec: 1578.65
//
Query:       EEA18713.1  [L=556]
Description: exo-beta-1,3-glucanase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.7e-68  228.5  24.3    2.7e-57  194.1   9.5    3.0  3  Pectate_lyase_3  Pectate lyase superfamily protein
     0.0024   17.5   0.9      0.059   13.1   0.0    2.7  2  End_N_terminal   N terminal extension of bacteriophage endosi
  ------ inclusion threshold ------
       0.03   14.0   0.2      0.061   13.0   0.2    1.4  1  TMEM71           TMEM71 protein family
      0.067   12.7   0.1        1.3    8.5   0.1    2.3  2  DUF1833          Domain of unknown function (DUF1833)


Domain annotation for each model (and alignments):
>> Pectate_lyase_3  Pectate lyase superfamily protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  194.1   9.5     6e-61   2.7e-57       1     215 []     123     346 ..     123     346 .. 0.96
   2 ?   -0.2   0.2      0.17   7.6e+02     118     184 ..     369     430 ..     350     460 .. 0.54
   3 !   43.1   2.1   9.4e-15   4.2e-11      10      73 ..     472     532 ..     463     548 .. 0.89

  Alignments for each domain:
  == domain 1  score: 194.1 bits;  conditional E-value: 6e-61
                      SEEG.GGGT---EEEEE-HHHHHHHH...................HTSS-EEE-SEEEEESS-EEE-SSEEEEES-TTTEEEEE-TT-SS--SE CS
  Pectate_lyase_3   1 frnV.kdyGakgDGvtDdtaaiqkais.............casatttgavVYfPaGtYlvsspiilksgvqLvGdgngrpvlkaaaafvgagli 80 
                      frnV +dyGa+++G+tD + aiq+ai+             + ++t ++avVY+PaGtYl+s+ i+l  g++LvGd+ ++p+lka+++f +++++
       EEA18713.1 123 FRNVvTDYGADNTGATDASKAIQNAINagpsnggpvrgsgNYGTTGQPAVVYLPAGTYLMSKNIQLLVGTVLVGDPINPPTLKATSSFPNDHIV 216
                      79999***************************************************************************************** PP

                      EES-TTT-..-EEEEEEEEEEEGGGG-SS---S..SEEEES-EEEEEEEEEEES-SSEEE-SSS---TT---SS--EEEE..ES-EEES-SS-S CS
  Pectate_lyase_3  81 dgdpyvsggsealiatnnfyrqirnlkiditav..apgatgihwqtaqatslenvefemseasgtkhqgifiengsggfl..ndlvfsglgdig 170
                          y+++  ++++ t nfy +i+n++id+tav  a + + ++w+++qat+l+nv+f+m+++s t h+g++ +++s++ +  ndl+f+g g++g
       EEA18713.1 217 ----YAKD--PNYGGTINFYIGIKNIIIDSTAVngATNIALLDWTVSQATQLSNVVFNMPDYS-TGHVGVTSQYDSNSNIilNDLTFNG-GAYG 302
                      ....6655..78999******************55555599**********************.9************77779*******.**** PP

                      EEES-EEEEEES-EEE-S--SEEE-TT-EEEEEEEEEESSSEEEE CS
  Pectate_lyase_3 171 iavgnqqftvrnitfnnattgievlwgwgwtlknvkinncegGid 215
                      ++++ qq++++ni+++++ttgi+++ g ++++++++++ + +Gid
       EEA18713.1 303 LKLSGQQWILKNIKTSGTTTGISAG-GFSVVCQACSFEYAATGID 346
                      ************************9.9****************96 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.17
                      ES-EEEEEEEEEEES-SSEEE-SSS---TT---SS--E...EEEES-EEES-SS-SEEES...-EEEEEES-E CS
  Pectate_lyase_3 118 tgihwqtaqatslenvefemseasgtkhqgifiengsg...gflndlvfsglgdigiavg...nqqftvrnit 184
                      +g    t+++  + +v++e+ +++g    + +  +gs+   g ++d +++g   + +  g   +  +t r +t
       EEA18713.1 369 KG----TNSGGAVNSVVLENVSYDG----TTVSMSGSTvlsGSVTDTWVYG---HLYSSGsssSSPVTGRTVT 430
                      33....6677777777777777775....2222223333334446766666...3333322224444444444 PP

  == domain 3  score: 43.1 bits;  conditional E-value: 9.4e-15
                      --EEEEE-HHHHHHHH......HTSS-EEE-SEEEEESS-EEE-SSEEEEES-TTTEEEEE-TT CS
  Pectate_lyase_3  10 kgDGvtDdtaaiqkaiscasatttgavVYfPaGtYlvsspiilksgvqLvGdgngrpvlkaaaa 73 
                       gDG+tDdta i++++   s+ ++ +v+YfPaGtY+v+++i ++ g  ++Gd+ g ++    ++
       EEA18713.1 472 YGDGSTDDTANINSIL---SKYAGCKVIYFPAGTYIVTNTIFIPAGSRIYGDAYGTAISAIGSN 532
                      59**************...**********************************88777665555 PP

>> End_N_terminal  N terminal extension of bacteriophage endosialidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.2     0.035   1.6e+02       4      30 ..     135     162 ..     132     172 .. 0.79
   2 !   13.1   0.0   1.3e-05     0.059       3      36 ..     473     506 ..     471     519 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.035
                     EEEEE-HHHHHHHHHHS-T.TS-EE-TT CS
  End_N_terminal   4 DGvtdDtdalsevlaaapv.gkkidGrG 30 
                      G td  +a++++++a p+ g  + G G
      EEA18713.1 135 TGATDASKAIQNAINAGPSnGGPVRGSG 162
                     599************9885145666666 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 1.3e-05
                     -EEEEE-HHHHHHHHHHS-TTS-EE-TT-EEEES CS
  End_N_terminal   3 GDGvtdDtdalsevlaaapvgkkidGrGltykvs 36 
                     GDG tdDt+ ++++l++ ++ k i     ty v+
      EEA18713.1 473 GDGSTDDTANINSILSKYAGCKVIYFPAGTYIVT 506
                     9****************99999998888888887 PP

>> TMEM71  TMEM71 protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.2   1.4e-05     0.061      45      79 ..     415     449 ..     375     460 .. 0.72

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 1.4e-05
      TMEM71  45 sfeccsidpltgsvlvCrrsPrlltnGyyvlteds 79 
                 s  + s  p+tg +++  rs  ll+nG y +te  
  EEA18713.1 415 SSGSSSSSPVTGRTVTTPRSSSLLSNGRYFITEKP 449
                 44567899************************975 PP

>> DUF1833  Domain of unknown function (DUF1833)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0     0.038   1.7e+02     102     127 ..      40      64 ..      20      83 .. 0.86
   2 ?    8.5   0.1    0.0003       1.3      45     100 ..     325     382 ..     306     409 .. 0.79

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.038
     DUF1833 102 aylstdlnaphveapielkvkdvsvd 127
                  + s+d+  ph +++i ++++d s++
  EEA18713.1  40 QFVSNDSYKPH-KTGIPFTLLDTSIQ 64 
                 57899******.***********996 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0003
     DUF1833  45 a..GkvvvftalaldlalPaededkvpeltlildNvgsvitdavegaavservielty 100
                    G  vv+ a++++ a    d  +v   t ++d  g  +  +++g+   + v +++ 
  EEA18713.1 325 SagGFSVVCQACSFEYAATGIDATGVSGTTTVIDSSGLNLGVFLKGTNSGGAVNSVVL 382
                 245789*****************************99999999999998886655554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (556 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       381  (0.0212505); expected 358.6 (0.02)
Passed bias filter:                      248  (0.0138323); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 3966.90
//
Query:       EEA18714.1  [L=264]
Description: hypothetical protein PMAA_009970 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (264 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       420  (0.0234257); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.27s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1929.83
//
Query:       EEA18715.1  [L=677]
Description: methionyl-tRNA synthetase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   3.7e-140  467.1   0.1   1.1e-137  458.9   0.1    2.1  1  tRNA-synt_1g  tRNA synthetases class I (M)
    7.6e-07   27.8   6.9    0.00015   20.2   0.0    3.6  4  tRNA-synt_1   tRNA synthetases class I (I, L, M and V)
    0.00011   22.2   0.4    0.00022   21.2   0.4    1.5  1  Anticodon_1   Anticodon-binding domain of tRNA
  ------ inclusion threshold ------
       0.19   12.0   0.0        0.5   10.7   0.0    1.6  1  DUF1108       Protein of unknown function (DUF1108)


Domain annotation for each model (and alignments):
>> tRNA-synt_1g  tRNA synthetases class I (M)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  458.9   0.1  2.6e-141  1.1e-137       1     390 [.      16     445 ..      16     446 .. 0.94

  Alignments for each domain:
  == domain 1  score: 458.9 bits;  conditional E-value: 2.6e-141
                   EEEEE--B--SS---HHHHH.HHHHHHHHHHHHHHTT-EEEEEEEE---SHHHHHHHHHTTS-HHHHHHHHHHHHHHHHHHTT---SEEEETTSHHH CS
  tRNA-synt_1g   1 vlvttalpYangklHlGhll.evisaDifaRykrlrgeevlfvcgtDehGtpielkAekegvtpeelvekvheeikelfkklnisfdkygrttseeh 96 
                   +l+t+alpY+n+++HlG+++ +v++aD+faRy+r+rg  +l++cg+De+Gt++e+kA +egv+peel++k+h+++k +++++ni+fd +grt + ++
    EEA18715.1  16 ILITSALPYVNNVPHLGNIIgSVLPADVFARYNRARGFPTLYICGSDEYGTATETKALEEGVSPEELCAKYHTIHKGIYDWFNIEFDIFGRTPTAHQ 112
                   69*********************************************************************************************** PP

                   HHHHHHHHHHHHHTT-EEEEEEEEEEETTT..TEEE-GGG-EE........-TTS-EE-TTSSB-E............................... CS
  tRNA-synt_1g  97 kelvqeifkklkekgliyekeieqlycpkd..erflpdryvegtCPkckseeargdqceecgkklepte......................linpks 169
                   +++vq++f+ l e+g+i+e+e++q ycp +   +fl+dr+veg+C  c++  argdqc++cg+ l+p e                      linp++
    EEA18715.1 113 TKIVQDVFRGLWENGYIEERETTQPYCPVEghATFLADRFVEGECSICGDPGARGDQCDKCGNLLDPLEpdakeggeegeeqdvearatgwLINPRC 209
                   ***************************9752268******************************9985444445555566666777777789***** PP

                   .......EEE.EEEEEE-GGGGHHHHHHHH.HH-TT..SHHHHHHHH.HHHHT----EE-ESS-SSS-EET.........TECCEEE-HHHHHHHHH CS
  tRNA-synt_1g 170 aisgskpevketehlffklskfekklkewieeeeke..leenvkkivkewlkegLkdlaisrdldwGipvP.........gaekkvlYVWldAligY 255
                   ++ g++pe ++t+hl+++l+++++k+  w+e+ +ke  ++ n+++iv++w+++gLk++ai+rd++wG+p+P           ++kv+YVW+dA igY
    EEA18715.1 210 KLDGATPEKRKTKHLYLRLDALKDKIVPWFEKVSKEndWSINTSSIVQSWIDRGLKPRAITRDIKWGVPIPtgiegldeeAYKNKVFYVWFDACIGY 306
                   ******************************98877778*************************************99987789************** PP

                   HHTTTTT-...T.TSGGGG.G--S......EEEEEGGGHHHHHTHHHHHHHH..TT----S-EEEE--EEE--------------HHHHHHH.H-HH CS
  tRNA-synt_1g 256 isatkelakkkg.eeekwkeyWakdkevelvhfigkdiikFHtifwPaillg..aelklpkkvvaheyltvegkKlSkSrgvvvkakealer.ldad 348
                   +s+t ++++ ++ e +kw+++W++ ++v+l +f+gkd+++FH+i++P  +lg   ++++++k++a+eyl++eg+K+SkS+gv+v+ + a ++ + +d
    EEA18715.1 307 VSITANYTDGDNlEGKKWEQWWKHPEQVSLFQFMGKDNVPFHSIIFPGSQLGsgMKWTQVHKISATEYLNYEGGKFSKSKGVGVFGTSAKDTgVGPD 403
                   ********55541567******99999***********************99888999*************************************** PP

                   HHHHHHHHHS-TTS-EEE-HHHHHHHHHHHCCCHHHHHHHHH CS
  tRNA-synt_1g 349 llRYylaaeapekkDldfswedfvervNseLadklgnlvnRv 390
                   ++R+yl++ +pe++D++f+w++fv ++N+eL ++lgnlv Rv
    EEA18715.1 404 IWRFYLLSRRPESSDTEFKWDEFVSTNNNELLKNLGNLVARV 445
                   *****************************************8 PP

>> tRNA-synt_1  tRNA synthetases class I (I, L, M and V)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.0   3.3e-08   0.00015      27      79 ..      18      71 ..      12      89 .. 0.88
   2 !    7.2   0.3   0.00028       1.3     363     444 ..     207     292 ..     200     332 .. 0.81
   3 !    2.4   0.0    0.0079        36     557     601 ..     375     421 ..     292     422 .. 0.77
   4 ?   -4.1   1.9      0.74   3.3e+03     431     468 ..     598     635 ..     596     658 .. 0.47

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 3.3e-08
  tRNA-synt_1 27 lvdgPPyvtGslHiGhalaktl.kdivirykrmkGkevlyvpGwDhaGlaieak 79
                 ++   Pyv+  +H+G+++ ++l  d+  ry+r +G+ +ly  G D  G a+e+k
   EEA18715.1 18 ITSALPYVNNVPHLGNIIGSVLpADVFARYNRARGFPTLYICGSDEYGTATETK 71
                 55667****************9669**************************986 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.00028
  tRNA-synt_1 363 pfcerskkpiiyrateqWfvrvkeladaalkavekvqfvpks...kekryaswl.eniqdWciSRqrwWGhriplfvsketeevvv 444
                  p c+  ++  + r t+  + r+++l+d+++   ekv+   ++   + +  +sw+ +  +  +i R+  WG++ip  ++   ee + 
   EEA18715.1 207 PRCKLDGATPEKRKTKHLYLRLDALKDKIVPWFEKVSKENDWsinTSSIVQSWIdRGLKPRAITRDIKWGVPIPTGIEGLDEEAYK 292
                  667777777788999***************9999888887774423345689994468999*************988777777666 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.0079
  tRNA-synt_1 557 rdeeGrKmSKslgNvidpldvikk.ygadalRltli.lsdvgrdinl 601
                  ++ eG K SKs+g  +  ++  ++ +g d+ R++l+   + ++d+++
   EEA18715.1 375 LNYEGGKFSKSKGVGVFGTSAKDTgVGPDIWRFYLLsRRPESSDTEF 421
                  56799********988877766543899*******977777777765 PP

  == domain 4  score: -4.1 bits;  conditional E-value: 0.74
  tRNA-synt_1 431 iplfvsketeevvvreelkelvagreeeeaekkaleke 468
                  i  ++++  +e+v r++  e +++  ++ a++k+ ek+
   EEA18715.1 598 IEEWREAFGGEEVRRQKALEAEKAAAKKLAKEKEKEKK 635
                  55566666666666554444433333332222222221 PP

>> Anticodon_1  Anticodon-binding domain of tRNA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.4   4.9e-08   0.00022       7     136 ..     475     633 ..     471     651 .. 0.66

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 4.9e-08
  Anticodon_1   7 elnklvkevteayeeyrfnkaasalyeffwndlcdwylelvkprlysesaedk..raaqevllevletllrllaPfmPfitEelwqr........... 91 
                  ++n+++ ++   ++  +++ a++++++    +l +  l+ +k +    ++e++   a+ ++ l  ++ l  ll+PfmP ++  ++++           
   EEA18715.1 475 QVNSYLTSYITFMDATKMRPALNDIMHI--SSLGNKLLQDNKLDNRLFTEEPDrcAAVINIALNHIHLLASLLSPFMPATSKSIFEQlgaqpearipd 570
                  6788999999999**************6..89******99985544444444432335599999999******************7678888888888 PP

  Anticodon_1  92 ........eeeelgkkesimlaewpe.kaeel.ekel..e........eeevellkeivkairkl 136
                           +++lg+++ +  +  p  k ee+ e +   e        e+e + +k++ k  +k 
   EEA18715.1 571 kwvsdvlkPGHKLGESKLL-FSLIPPtKIEEWrE-AFggEevrrqkalEAEKAAAKKLAKEKEKE 633
                  8888777644444554444.44455546666642.222313444333433333333333333332 PP

>> DUF1108  Protein of unknown function (DUF1108)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00011       0.5      52      81 ..     222     251 ..     218     253 .. 0.92

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00011
     DUF1108  52 selyialdilrdviyewieentderdklin 81 
                 ++ly+ ld+l+d i  w e+ + e+d  in
  EEA18715.1 222 KHLYLRLDALKDKIVPWFEKVSKENDWSIN 251
                 689***********************9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (677 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2059  (0.114842); expected 358.6 (0.02)
Passed bias filter:                     1122  (0.0625802); expected 358.6 (0.02)
Passed Vit filter:                       149  (0.00831056); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.93u 0.31s 00:00:01.24 Elapsed: 00:00:00.51
# Mc/sec: 3983.96
//
Query:       EEA18716.1  [L=397]
Description: BNR/Asp-box repeat domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.4e-08   33.1   0.0      1e-06   28.3   0.0    2.3  2  BNR_2           BNR repeat-like domain
    3.9e-07   29.1   9.3        1.8    8.9   0.5    5.3  4  BNR             BNR/Asp-box repeat
     0.0066   15.3   1.2       0.69    8.6   0.2    3.1  3  Sortilin-Vps10  Sortilin, neurotensin receptor 3,
  ------ inclusion threshold ------
      0.021   14.9   0.2        9.5    6.2   0.0    3.4  4  Mo-co_dimer     Mo-co oxidoreductase dimerisation domain


Domain annotation for each model (and alignments):
>> BNR_2  BNR repeat-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.7   0.0    0.0018       7.9      71     152 ..      87     176 ..      71     186 .. 0.49
   2 !   28.3   0.0   2.3e-10     1e-06      22     179 ..     166     323 ..     161     336 .. 0.79

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0018
                 EETT--HHT----EEEESSTTSS----EHHHGGEEEEEE-SS--..EE--...T--EEEEEE.............SS--EEEEEEEESSTTSS-EE CS
       BNR_2  71 gvsvggwagskitrvtSkDdGktWsaprrlpkspflnisgpvknkpiqla...dGrlilPsshe...........lagkwrallelsddggktWkk 152
                  ++ + +a +     +S D+G+++    ++ ++      g + n ++ l+   +G ++ + + +            ++++r+ ++ s+d g+tW+ 
  EEA18716.1  87 RQGGRMDALRILKISRSLDGGQSFHDFSEVYRG-----HGEIDN-LHILEiapEGHVLAAFRNHdfghnragdlaGITHFRITVFESRDAGVTWRY 176
                 444444444444445555555555555555555.....333333.222222335555555333334444444455555566666666666666654 PP

  == domain 2  score: 28.3 bits;  conditional E-value: 2.3e-10
                 EEEETTEEE.EEEEEE-TTS-...BTTEEEEEEEEEEETTTEEEEEEEEEETT--HHT----EEEESSTTSS----E.......HHHGGEEEEEE-SS- CS
       BNR_2  22 vsvsdkgsneWsapqvvadreqsrearkklgNPvlfqdpsgtliLfykvgvsvggwagskitrvtSkDdGktWsapr.......rlpkspflnisgpvk 113
                  s  ++++ +W     +a++     +    + P +    +g++ L+y+    + +  ++    v+S D+Gk+Ws+pr       r  ++    ++g+ +
  EEA18716.1 166 ES--RDAGVTWRYLSEAAQKS---DPPLGIWEPFMRMGLQGEVQLIYSHEFAPDDQRTML---VSSYDQGKSWSSPRciegyqdRFRDG----MTGITQ 252
                 44..77777888888888888...999999999999988********9999999998888...9*************666555555555....666666 PP

                 -..EE--T--EEEEEE...SS--EEEEEEEESSTTSS-EE----S....SSEEEEEEEE.EEETTEEEEEE CS
       BNR_2 114 nkpiqladGrlilPsshe.lagkwrallelsddggktWkkgrvve....qisgeiqpsilvekdgslvala 179
                 +  +++++  l+++  ++  a ++ +   +s d+g tW+  + v     +++++  p i+   dgs+ +++
  EEA18716.1 253 TIDTATSQIALVMCFETTrYAPHFNVEAAVSYDDGATWQHRHQVYtprrRGHNAGAPQITSFGDGSMACVF 323
                 644566777888885555478889999999********999998889886667777888777888887776 PP

>> BNR  BNR/Asp-box repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.8   0.1    0.0041        18       3      11 ..     103     111 ..     101     112 .. 0.89
   2 !    7.7   0.0   0.00096       4.3       1      11 [.     165     175 ..     165     176 .. 0.87
   3 !    8.9   0.5    0.0004       1.8       3      11 ..     223     231 ..     221     232 .. 0.91
   4 !    8.7   0.1   0.00046       2.1       2      11 ..     282     291 ..     281     292 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0041
                 ESSTTSS-E CS
         BNR   3 StDgGktWs 11 
                 S DgG++++
  EEA18716.1 103 SLDGGQSFH 111
                 99******8 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.00096
                 EEESSTTSS-E CS
         BNR   1 yyStDgGktWs 11 
                 + S+D G tW 
  EEA18716.1 165 FESRDAGVTWR 175
                 57********6 PP

  == domain 3  score: 8.9 bits;  conditional E-value: 0.0004
                 ESSTTSS-E CS
         BNR   3 StDgGktWs 11 
                 S+D+Gk+Ws
  EEA18716.1 223 SYDQGKSWS 231
                 99******9 PP

  == domain 4  score: 8.7 bits;  conditional E-value: 0.00046
                 EESSTTSS-E CS
         BNR   2 yStDgGktWs 11 
                 +S+D G tW+
  EEA18716.1 282 VSYDDGATWQ 291
                 7********9 PP

>> Sortilin-Vps10  Sortilin, neurotensin receptor 3,
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0      0.28   1.3e+03       3      21 ..     100     118 ..      99     135 .. 0.75
   2 !    8.6   0.2   0.00015      0.69     377     432 ..     162     231 ..     152     234 .. 0.64
   3 !    3.0   0.0     0.008        36     297     311 ..     277     291 ..     261     298 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.28
                     EEEESSTTSS-EE-GGGGT CS
  Sortilin-Vps10   3 vyiSeDeGktwkkvkeklk 21 
                     + +S D G+++++ +e+ +
      EEA18716.1 100 ISRSLDGGQSFHDFSEVYR 118
                     6678888888888776654 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.00015
                     -EEEEESSSSSS-EEEESS-EE...........EEEEGGGTEEEEEE-....SSS-B-EEEEESSTTSSEE CS
  Sortilin-Vps10 377 adtfiSrDaGltWkevlkgahk...........yefGDqGsiivavkd....eeketkelsYSlDeGktWe 432
                       +f SrDaG+tW+   + a k           + +G qG + ++ ++    + ++ + l  S D+Gk+W+
      EEA18716.1 162 ITVFESRDAGVTWRYLSEAAQKsdpplgiwepfMRMGLQGEVQLIYSHefapD-DQRTMLVSSYDQGKSWS 231
                     57899********9877766542222222222245788888877777745422.45556666788888886 PP

  == domain 3  score: 3.0 bits;  conditional E-value: 0.008
                     -EEEEEESSTTS-EE CS
  Sortilin-Vps10 297 klktkItfddGrtWe 311
                     +++  +++ddG+tW+
      EEA18716.1 277 NVEAAVSYDDGATWQ 291
                     567788999999997 PP

>> Mo-co_dimer  Mo-co oxidoreductase dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   0.0    0.0021       9.5      22      59 ..      70     111 ..      50     122 .. 0.84
   2 ?   -2.4   0.0      0.98   4.4e+03      51      61 ..     167     177 ..     155     186 .. 0.68
   3 ?    0.5   0.0      0.12   5.6e+02      51      69 ..     223     242 ..     218     266 .. 0.75
   4 ?    3.3   0.0     0.017        77      49      70 ..     281     302 ..     277     342 .. 0.78

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0021
                  E-S....EEEEEEEEEE-STT-....-EEEEEEESSTTSS-E CS
  Mo-co_dimer  22 vklkeaeetytikGyaysGgGr....ritrvevsldkGksWk 59 
                  ++l+  ++   + G+ +  gGr    ri ++  sld+G+s++
   EEA18716.1  70 IRLARLHDGTILAGFTWRQGGRmdalRILKISRSLDGGQSFH 111
                  5666666677789********988889************987 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.98
                  ESSTTSS-EE- CS
  Mo-co_dimer  51 sldkGksWkla 61 
                  s d G +W+  
   EEA18716.1 167 SRDAGVTWRYL 177
                  7899****864 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.12
                  ESSTTSS-EE-E.EESSSSS CS
  Mo-co_dimer  51 sldkGksWklae.ieyeedk 69 
                  s d+GksW+  + ie  +d+
   EEA18716.1 223 SYDQGKSWSSPRcIEGYQDR 242
                  78******987624444444 PP

  == domain 4  score: 3.3 bits;  conditional E-value: 0.017
                  EEESSTTSS-EE-EEESSSSS- CS
  Mo-co_dimer  49 evsldkGksWklaeieyeedke 70 
                   vs d+G++W+  +  y+ ++ 
   EEA18716.1 281 AVSYDDGATWQHRHQVYTPRRR 302
                  59*********98877776654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       341  (0.0190195); expected 358.6 (0.02)
Passed bias filter:                      297  (0.0165653); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 2531.83
//
Query:       EEA18717.1  [L=211]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.3e-20   72.1  25.8    2.9e-15   56.5   9.7    2.1  2  PGA2            Protein trafficking PGA2
  ------ inclusion threshold ------
      0.057   13.3   0.0      0.082   12.8   0.0    1.2  1  DUF4271         Domain of unknown function (DUF4271)
       0.23   11.0   0.8        0.8    9.2   0.0    2.1  2  SieB            Super-infection exclusion protein B
       0.36   10.6  20.6       0.98    9.2  20.6    1.6  1  SpoIIIAH        SpoIIIAH-like protein
       0.42    9.6  15.0       0.59    9.1  15.0    1.2  1  SLC12           Solute carrier family 12
        1.4    7.8  11.8        1.7    7.5  11.8    1.3  1  XRN_M           Xrn1 helical domain
        2.3    8.2  10.7        3.2    7.7  10.7    1.2  1  Neur_chan_memb  Neurotransmitter-gated ion-channel transmembr
        3.1    6.8  23.9        4.2    6.3  23.9    1.0  1  LAP1C           Lamina-associated polypeptide 1C (LAP1C)
         10    5.1   8.9         14    4.6   8.9    1.3  1  Membralin       Tumour-associated protein


Domain annotation for each model (and alignments):
>> PGA2  Protein trafficking PGA2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.5   9.7   1.4e-18   2.9e-15       3     102 ..      28     132 ..      26     143 .. 0.72
   2 !   22.4  19.1   4.7e-08   9.3e-05      39     138 .]     108     203 ..     105     203 .. 0.61

  Alignments for each domain:
  == domain 1  score: 56.5 bits;  conditional E-value: 1.4e-18
        PGA2   3 nlsesfssltakdwirlvlivggYlllRPYleklfkklqekqrekeeekeeaeekaa.........kkakvspnalRggeaksgesdedddegeeeedv 92 
                 +++ +++  ++++w+r+++iv gY++lRP +e +fk+l+e+++ keee+++ +++++         kk+k + n+lR g+++ +es +++ ++e+   v
  EEA18717.1  28 DFQDYVATPKVRHWLRIIVIVAGYIMLRPAIELFFKWLFERKNSKEEEEQKRKKEEEdkkleeeglKKPKKDGNSLRVGTKT-EESKTEEKKSEK---V 122
                 56777888899*******************************9999888877776667799****************88754.333333333333...3 PP

        PGA2  93 akasgvpewg 102
                 ++++g+++  
  EEA18717.1 123 QESKGGKKTT 132
                 3332222222 PP

  == domain 2  score: 22.4 bits;  conditional E-value: 4.7e-08
        PGA2  39 klqekqrekeeekeeaeekaakkakvspnalRggeak.sgesdedddegeeeedvakasgvpewgkkarkrqkkvlkkleeeaeerkkeeeddkdiael 136
                 k  e ++e+++ ++ +e k  kk + + n+ +  +++ s+e +++d+  e+  +  +asgv ewg+ arkr++++  + e++   +++++ d++ + el
  EEA18717.1 108 KTEESKTEEKKSEKVQESKGGKKTTANENTSKKNNKTkSDEYENSDQ--EDYAEKIRASGVLEWGRDARKRKQRQQVEAEQQ---QQQKKIDEEKLLEL 201
                 44444444444444444444455555555555555442344444443..455568899************977665554444...45889999999999 PP

        PGA2 137 Le 138
                 L+
  EEA18717.1 202 LD 203
                 96 PP

>> DUF4271  Domain of unknown function (DUF4271)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   4.1e-05     0.082      75     119 ..      27      72 ..      17      78 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 4.1e-05
     DUF4271  75 slfgsyla.ssllllliiflilllylllKlllykllgwlFfdkkki 119
                   f++y a + +  +l i++i+++y++l+  ++ ++ wlF+ k+  
  EEA18717.1  27 HDFQDYVAtPKVRHWLRIIVIVAGYIMLRPAIELFFKWLFERKNSK 72 
                 34444555589999***************************99876 PP

>> SieB  Super-infection exclusion protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.0    0.0004       0.8      30      74 ..      37      81 ..      14      90 .. 0.74
   2 ?   -0.8   0.2      0.47   9.3e+02      59      76 ..     177     194 ..     164     204 .. 0.62

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0004
        SieB 30 eyglwiglvflisiayllaqvvskllaeikekikkkreqkkvekk 74
                + ++w+ ++++++  ++l  ++  +++++ e+ ++k e+++ +kk
  EEA18717.1 37 KVRHWLRIIVIVAGYIMLRPAIELFFKWLFERKNSKEEEEQKRKK 81
                4579******************************66666555543 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.47
        SieB  59 kekikkkreqkkvekklk 76 
                 k++++ + eq++++kk++
  EEA18717.1 177 KQRQQVEAEQQQQQKKID 194
                 445555555555555553 PP

>> SpoIIIAH  SpoIIIAH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2  20.6   0.00049      0.98       9     109 ..      42     164 ..      40     208 .. 0.51

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00049
                 XXXXXXXXXXXXXXXXX............XXXXXXXXXXXXXXXXXXXX.....................XXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
    SpoIIIAH   9 LalmiavagYlnftedsgk..........kaaetaeteqeesekaeigd.....................dkekdessaasaeaesssetesesseksd 76 
                 L ++++vagY+      +           +++e+++++++e+e++++++                     +k+++++s++ +e++  ++t+++++++++
  EEA18717.1  42 LRIIVIVAGYIMLRPAIELffkwlferknSKEEEEQKRKKEEEDKKLEEeglkkpkkdgnslrvgtkteeSKTEEKKSEKVQESKGGKKTTANENTSKK 140
                 66899******999986669*9**999887777777777788888888888888888888888775544322222222222222222222222222222 PP

                 XXXXXXXXX...XXXXXXXXXXX--HHHHHHHH CS
    SpoIIIAH  77 iassdedeadeltsetasaaasasdyfaeakle 109
                 + +         t++++ ++++++dy ++++ +
  EEA18717.1 141 NNK---------TKSDEYENSDQEDYAEKIRAS 164
                 222.........223333333334444443332 PP

>> SLC12  Solute carrier family 12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1  15.0    0.0003      0.59     116     247 ..      52     194 ..      44     202 .. 0.42

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0003
       SLC12 116 aiLrlkegldvsellqeeeeeeeekekkeaeese.keeeekkkakkkklle....ekskekeekekleekdsnlslseekkeeekekkkekkkkkekke 209
                 ++Lr + +l ++ l+++++++eee++k+++ee++ k eee  k+ kk+  +    +    k+e++k+eek+s++ ++++  ++++ +++++kk++++k+
  EEA18717.1  52 IMLRPAIELFFKWLFERKNSKEEEEQKRKKEEEDkKLEEEGLKKPKKDGNSlrvgT----KTEESKTEEKKSEKVQESKGGKKTTANENTSKKNNKTKS 146
                 66777777777777777766665555444444443222222222222222232331....233333333333333333333222333333333222222 PP

       SLC12 210 klkkkekslllkeaskee..........kevleeitqfqkkqkkgtiD 247
                 ++ +++++  ++e+ +++          k+ +++  + +++q+++ iD
  EEA18717.1 147 DEYENSDQEDYAEKIRASgvlewgrdarKRKQRQQVEAEQQQQQKKID 194
                 222222222222222222455677777744444444444455555555 PP

>> XRN_M  Xrn1 helical domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5  11.8   0.00087       1.7      81     196 ..      75     193 ..      15     205 .. 0.60

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.00087
       XRN_M  81 rkrkeredrkekklakeeeaskedaaneeaavaeeklseskvaksaeaeaeaeaeaeaeakaekekrekaekeleeseeeeeeeDkvr...LgeeGyke 176
                 +++k+++++++kkl++e  ++ +++ n+ +  +++++s+++ +ks+++++++  + +++++++++k++k+++++ e++++e++ +k+r   + e G   
  EEA18717.1  75 EEQKRKKEEEDKKLEEEGLKKPKKDGNSLRVGTKTEESKTEEKKSEKVQESKGGKKTTANENTSKKNNKTKSDEYENSDQEDYAEKIRasgVLEWGRDA 173
                 122222222222222222222222222222333333344444446666666666667777777778888888888888889999999933334566677 PP

       XRN_M 177 RYYkekfevsseeieqrrev 196
                 R  k++ +v+ e+ +q++++
  EEA18717.1 174 RKRKQRQQVEAEQQQQQKKI 193
                 77777777777777777765 PP

>> Neur_chan_memb  Neurotransmitter-gated ion-channel transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7  10.7    0.0016       3.2     104     220 ..      62     195 ..      46     201 .. 0.48

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0016
                     HHHC--------------.-------------------............-------------------SS---TTGGG--..........---- CS
  Neur_chan_memb 104 prllfmkrpsevkdnekklssgasseaeelilskskse............skkaklseeqgsekastckckckegeeaspstqlsk.....eels 181
                      ++lf +++s++++++k++++ + ++ ee  l+k+k++            sk++++++e+++e++  +k++ +e++ +++++++s+      +  
      EEA18717.1  62 FKWLFERKNSKEEEEQKRKKEEEDKKLEEEGLKKPKKDgnslrvgtkteeSKTEEKKSEKVQESKGGKKTTANENTSKKNNKTKSDeyensDQED 156
                     46666666666666666665555554444444444443333333332222333333333333333333333322222222222222333232222 PP

                     -TTTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Neur_chan_memb 182 pelkkavegvkyiadhlraededksvkedwkyvamviDr 220
                      + k   +gv    +  r++++ ++v+ + ++  ++iD 
      EEA18717.1 157 YAEKIRASGVLEWGRDARKRKQRQQVEAEQQQQQKKIDE 195
                     233333345555557777777777777777777777774 PP

>> LAP1C  Lamina-associated polypeptide 1C (LAP1C)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3  23.9    0.0021       4.2      69     204 ..      69     200 ..      63     205 .. 0.68

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0021
                 ..XXXXXXXXXXXX..........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXX......XXXXXXXXXXXXXXXXXXXX CS
       LAP1C  69 kdetEeedsessqsgeeghklsseslgeekldsedsvsssdktgradaqleessaalseeasdrtaasqepsaadsqeaqssghskaeqeeqdtlrrtr 167
                 k+ +Eee+++ +++ ee++kl+ e l +++ + ++s+  + kt +++++ ++ s +++e+++ ++++ +e++ +++++++s+++++++qe+ + ++r+ 
  EEA18717.1  69 KNSKEEEEQKRKKE-EEDKKLEEEGL-KKPKKDGNSLRVGTKTEESKTEEKK-SEKVQESKGGKKTTANENTSKKNNKTKSDEYENSDQEDYAEKIRA- 163
                 33444444444444.45555555555.5777888999999999888887555.45555555555555555566689999***********99999994. PP

                 X..XXXX..XXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       LAP1C 168 llvpeaeshqqetelleeskesaqdtlrkskkksfvk 204
                   v e + + ++ +++++ + ++q++ +k++++++++
  EEA18717.1 164 SGVLEWGRDARKRKQRQQVEAEQQQQQKKIDEEKLLE 200
                 5577777677777777777778888888888888776 PP

>> Membralin  Tumour-associated protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   8.9     0.007        14      95     177 ..      70     155 ..      47     206 .. 0.49

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.007
   Membralin  95 sekeeesekkisisenkkvllkeasvtlleesvlevsl...eaeeeekessslkkeeelrsveliensslktnlklledleisele 177
                 ++keee++k+ +++e+kk   +  ++ +++ ++l+v +   e+++eek+s+++++++  +++++ en+s k+n ++ ++ e+s++e
  EEA18717.1  70 NSKEEEEQKRKKEEEDKKLEEEGLKKPKKDGNSLRVGTkteESKTEEKKSEKVQESKGGKKTTANENTSKKNNKTKSDEYENSDQE 155
                 33334444444444444444444444444444444444000444444444444333333334444443333333333333222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (211 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3649  (0.203525); expected 358.6 (0.02)
Passed bias filter:                      899  (0.0501422); expected 358.6 (0.02)
Passed Vit filter:                       217  (0.0121033); expected 17.9 (0.001)
Passed Fwd filter:                        68  (0.00379274); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 1.06u 0.37s 00:00:01.43 Elapsed: 00:00:00.56
# Mc/sec: 1141.08
//
Query:       EEA18718.1  [L=366]
Description: extracellular protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
     0.0036   17.3   1.6      0.017   15.1   0.0    2.7  2  Glyco_hydro_61  Glycosyl hydrolase family 61
  ------ inclusion threshold ------
      0.054   14.1   0.6       0.18   12.4   0.0    2.0  2  LPMO_10         Lytic polysaccharide mono-oxygenase, cellulos


Domain annotation for each model (and alignments):
>> Glyco_hydro_61  Glycosyl hydrolase family 61
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   1.9e-06     0.017     125     177 ..     118     165 ..      20     194 .. 0.84
   2 ?   -1.1   0.7      0.17   1.5e+03      26      91 ..     280     359 ..     250     365 .. 0.47

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 1.9e-06
                     CEEEEE--TTB-SEEEEEEEEEEE-TTTTSTT--EEEEEEEEEEEESS-SB.- CS
  Glyco_hydro_61 125 aklsvtiPaslapGeYllRhEiiALhsagskggaQfYpsCaqleVtgsgtalp 177
                     +++++tiP++ ++G+ l     +A    ++ g+ ++Y++Caq++++g+++++ 
      EEA18718.1 118 SSYNFTIPSDAPSGQAL-----FAWTWFNKIGNREMYMNCAQVTIEGGSKSKR 165
                     68899999999999865.....6888888999**************9776322 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.17
                     --SSS--BGGTTSCHHCCSTTB.--SSBEEEETTSEEEEEEES...............SC-TT--S-EEEEEEE-SSS-GTT CS
  Glyco_hydro_61  26 kakdngpvtdvtspdiaCnkag.paaavaevkaGdtvtfewke...............kwissHkGpvlvYlakcasgddck 91 
                     + ++++p    ts++ +  ++  paa+++  kaG + t++  +               +w++  +G +l+++ ++a g++c+
      EEA18718.1 280 SIASSSPTL-TTSTSAQATNTIpPAASSIAPKAGGSGTATSGQacsnngaivcgangtTWSMCNQG-ALTFMGSVAAGTSCS 359
                     444444442.22222222222224444445555555555554444444333333332236655556.456666665555555 PP

>> LPMO_10  Lytic polysaccharide mono-oxygenase, cellulose-degrading
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   2.1e-05      0.18      91     194 .]      67     155 ..      40     155 .. 0.79
   2 ?   -1.7   0.1      0.43   3.8e+03      23      68 ..     319     361 ..     300     365 .. 0.59

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2.1e-05
                 ..EEEESESEEEEEEEESS-S-EEEEEEEEE-TT--TTS-HHGGGEEEBEEEESSCEESCCTCEEEEEEEEETSS--EEEEEEEEEEE.TSTSSSEEEE CS
     LPMO_10  91 vqttytegseiefeveltapHktghfefyitkecfdptkpLtwadlepfatvsdpksrapskeatyyrkvklPegrtgehvllqvWqyvtanstqeaFy 189
                  ++tyt+gse+ ++   +a H  g  ++ ++ +        t+          ++ ++ ++ +++y  ++++P++    + l++ W++  +    e ++
  EEA18718.1  67 SVATYTAGSEYGMSLSGSATHGGGSCQLSLSYDTGKT---FTVI---------QSMEGGCPLTSSY--NFTIPSDAPSGQALFA-WTWFNKIGNREMYM 150
                 5789999999999999999999999999999777766...3443.........1222237788899..******99999999*9.9996666679**** PP

                 EEEEE CS
     LPMO_10 190 nCaDv 194
                 nCa v
  EEA18718.1 151 NCAQV 155
                 **976 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.43
                 TTTHHHHSHH....HHTHGHHHTTTG-EEET.SHHHHSSTT-TTTTT CS
     LPMO_10  23 tspqspnseavearCggaavqyeensvekek.rlkaappdgglcgag 68 
                   + + n++a    Cg + + + + +  + +  +   +++g+ c+ g
  EEA18718.1 319 SGQACSNNGA--IVCGANGTTWSMCN--QGAlTFMGSVAAGTSCSNG 361
                 3344455555..77855555555444..3446778888888888754 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (366 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       827  (0.0461264); expected 358.6 (0.02)
Passed bias filter:                      316  (0.0176251); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.35s 00:00:00.97 Elapsed: 00:00:00.48
# Mc/sec: 2310.86
//
Query:       EEA18719.1  [L=710]
Description: UV-endonuclease UVE-1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
   4.5e-112  373.8   0.0   6.5e-112  373.3   0.0    1.2  1  UvdE         UV-endonuclease UvdE
  ------ inclusion threshold ------
          5    7.0  10.0       0.16   11.8   2.7    2.5  2  Shugoshin_C  Shugoshin C terminus


Domain annotation for each model (and alignments):
>> UvdE  UV-endonuclease UvdE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  373.3   0.0  7.3e-116  6.5e-112       1     275 [.     213     519 ..     213     520 .. 0.99

  Alignments for each domain:
  == domain 1  score: 373.3 bits;  conditional E-value: 7.3e-116
        UvdE   1 lGyvclavelrnaspavtlsrtrrlklikrer............................keklkelakaNlkdllkllkynaaygirllRlSSslvPl 71 
                 lGy+cl ++lr a+p+v++srt+r+++i ++r                            ++ ++ l+ aN++d++k+l++n +ygi++lRlSS+++P+
  EEA18719.1 213 LGYACLCTYLRYANPPVFSSRTCRIASILENRhplqdpsqpfhatknrpdrkqpadhargQAYVEALGLANARDIVKMLRWNDKYGIKFLRLSSEMFPF 311
                 8****************************999******************************************************************* PP

        UvdE  72 ashpevgykletalaeeleevGelakelglRltfHPeqftllnSdrkevtesairdlayHdklldalklaeqq..davliiHvGGkfgdkeaalerfke 168
                 ash  +gykl+++++e+l+e+G++a+elg+Rlt+HP+qft+l+S+rkev es+irdl++H +ll +lkl++qq  dav+i+H+GG fgdk+a+l+rf+e
  EEA18719.1 312 ASHEIYGYKLAPFASEVLAEAGRVAAELGHRLTMHPGQFTQLGSPRKEVIESSIRDLEFHSELLRLLKLPPQQnrDAVMILHMGGVFGDKAATLDRFRE 410
                 ************************************************************************999************************ PP

        UvdE 169 nikrlpdsvkerlvLENDdksytvadlLpvceelniPlVlDyHHhnvld....lreesldeslplveriveTWerkgikqkvHlSepldgkavrahkdr 263
                 n+k l++++k+r+vLENDd+s++v+dlLp+ceelniPlVlDyHHhn+ +    lre++ld+++ l +ri++TW+rkgi+qk+H+Sep    a++++++r
  EEA18719.1 411 NYKGLSQDIKNRIVLENDDVSWSVHDLLPICEELNIPLVLDYHHHNIIFdsdkLREGTLDIMQ-LYDRIRATWTRKGITQKMHYSEPEPT-AITPRQRR 507
                 ************************************************999999*******99.8**********************766.******** PP

        UvdE 264 khadrvldllea 275
                 kh+ rv +l+++
  EEA18719.1 508 KHNTRVYNLPPC 519
                 **********98 PP

>> Shugoshin_C  Shugoshin C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.8       1.1   9.5e+03       2      10 ..     648     656 ..     647     657 .. 0.68
   2 ?   11.8   2.7   1.8e-05      0.16       1      15 [.     693     706 ..     693     706 .. 0.95

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 1.1
  Shugoshin_C   2 RpsRrarkv 10 
                  R++R ++++
   EEA18719.1 648 RKRRKSEAS 656
                  888877665 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 1.8e-05
  Shugoshin_C   1 gRpsRrarkvvsYKE 15 
                  +R+sRra k v+Y+E
   EEA18719.1 693 TRRSRRA-KKVNYAE 706
                  5******.******9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (710 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1477  (0.0823805); expected 358.6 (0.02)
Passed bias filter:                      627  (0.0349713); expected 358.6 (0.02)
Passed Vit filter:                       111  (0.00619109); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.81u 0.33s 00:00:01.14 Elapsed: 00:00:00.49
# Mc/sec: 4334.32
//
Query:       EEA18720.1  [L=527]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-34  119.7  32.1    1.3e-34  119.7  32.1    2.0  2  MFS_1     Major Facilitator Superfamily
    1.1e-13   50.8   2.8    1.1e-13   50.8   2.8    2.9  3  Sugar_tr  Sugar (and other) transporter
  ------ inclusion threshold ------
       0.43   10.9   3.1       0.45   10.8   0.3    2.4  2  DUF4112   Domain of unknown function (DUF4112)
        2.1    8.6   7.1       0.35   11.1   0.5    3.0  3  DUF423    Protein of unknown function (DUF423)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.7  32.1     3e-38   1.3e-34       3     351 ..      92     474 ..      90     476 .. 0.79
   2 ?    2.0   5.8     0.018        80     122     173 ..     460     511 ..     458     526 .. 0.63

  Alignments for each domain:
  == domain 1  score: 119.7 bits;  conditional E-value: 3e-38
       MFS_1   3 laaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlgag 100
                 ++++ s++a++i+++ ++  +  ++ +s  ++ l +t+y lg a++ l+++++s+ +Gr+  +l+ +++ a++++  + ++  + ++l+ r+++G+g++
  EEA18720.1  92 FTTMGSTWASTIYNSGIT-QIEAQFDVSSEVALLGMTFYLLGNAFGPLLFAPVSEAYGRKISVLIPFFMCAISSFGTA-TAKDTqTVLITRFFAGIGGS 188
                 789999************.899***************************************99999999999944444.4667779************* PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg...Wravfyilaivsllafvlfllllpeepperkrkspkeee........ 188
                 a + + + ++ad++p+++rg a+  +++++ +G++l+pl+gg+l+ +l    Wr+  y+ +i++l+ +   ++++ e++p+    +++ ++        
  EEA18720.1 189 APLCNTGGVLADIWPPQHRGVALLTYGMAVVAGPLLAPLVGGALVVNLEhdgWRWGEYLTGILLLVIMAADIFYIEESYPPILLTRKANRLrkltgnwa 287
                 *********************************************9998999*****************999***999999999999999899999999 PP

       MFS_1 189 ............kgtgpaplvpawkallkdpvlwillialllfffgfsg...lltllplylqevlgls....glllaglllallalvgailallagrls 268
                             k+++++ l+ + ++l  +    i++++ l+++f++++   + + +p+ + ev+g++    +      l+ l+ l+g+++a ++  +s
  EEA18720.1 288 lhskhqendqslKSWVRSYLLVPMEMLIDP----ICFLINLYASFVYAIiylTIAIFPIEFEEVRGWNsvvgS------LPFLGILIGLFFAAIVLMWS 376
                 999877755555333333333323333333....466666666667777333666666658*******44443......45555555555544444444 PP

       MFS_1 269 dr............lgrrrrlllallllllaalglallavtssavllllvlvl....iGfglgfv.fpsllalasdlappeeagtasglfntagslgga 350
                 +               ++ rl+ ++++ ++++ gl+++++ts+ +++++++ +    iG+g++++ ++s+ +l++ ++    a++a++++++++s+ + 
  EEA18720.1 377 QTfyvkrliannnkPVPEARLVSMMIGSFFFSGGLFIIGWTSDRSIHWIAFCIggacIGLGFFTIfQSSISYLVDVYL--MLAASALAANMLMRSVLAG 473
                 33333346666676667************************9999999977777777***666661555555555555..8999999999999995554 PP

       MFS_1 351 l 351
                  
  EEA18720.1 474 A 474
                 4 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.018
       MFS_1 122 aigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllp 173
                 a++  +++ s+ a   pl++ +++++lg  ++  +l+++++ ++ + +l++ 
  EEA18720.1 460 ALAANMLMRSVLAGAFPLFANAMVTNLGIGWACSVLGFIAAAMIPIPFLFYI 511
                 5566666666666677777777777777777777777777777665555554 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.8   2.8   2.6e-17   1.1e-13      25     194 ..     101     266 ..      84     309 .. 0.80
   2 ?   -0.9   0.2      0.13   5.6e+02     138     159 ..     353     374 ..     328     390 .. 0.78
   3 ?  -11.3  16.2         4   1.8e+04     327     437 ..     400     510 ..     395     517 .. 0.51

  Alignments for each domain:
  == domain 1  score: 50.8 bits;  conditional E-value: 2.6e-17
                 HHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHH CS
    Sugar_tr  25 llkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlv 123
                 ++   +n g ++ +++ + ss    l + ++l+G ++G l++ ++++ +GRk s li  +++ i+++ +a+ak    ++ +++ R+++Gig  +  + +
  EEA18720.1 101 STI--YNSGITQIEAQFDVSSEVALLGMTFYLLGNAFGPLLFAPVSEAYGRKISVLIPFFMCAISSFGTATAK---DTQTVLITRFFAGIGGSAPLCNT 194
                 333..4444444444444466677888999*******************************************...89*************99999999 PP

                 HHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHH.HHHHHGGGS--- CS
    Sugar_tr 124 PmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpal.lllilllflPES 194
                    ++ i p+++Rg     y +a+++G l+a  +g +l  + ++dgwr+  +l+ ++ l ++++ ++ ++ES
  EEA18720.1 195 GGVLADIWPPQHRGVALLTYGMAVVAGPLLAPLVGGALVVNLEHDGWRWGEYLTGILLLvIMAADIFYIEES 266
                 99**********************************99777777******9999887640444555777777 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.13
                 HHHHHHHHHHHHHHHHHHHHHH CS
    Sugar_tr 138 alvslyqlaitfGilvaaifgl 159
                  ++sl  l+i +G ++aai+ +
  EEA18720.1 353 VVGSLPFLGILIGLFFAAIVLM 374
                 5678888888888888887755 PP

  == domain 3  score: -11.3 bits;  conditional E-value: 4
                 HHHHHHHHH...HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTH..HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHH CS
    Sugar_tr 327 maicfvilg.ivalllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvR..skalaiavavnwlanflisllfpiiteaigggyvflvf 422
                 m+i  ++++ + ++++ +++     +  +++++  a+ +lg+ +++   +s l +  +   ++ala  + +  +   +  l+   ++ ++g g+   v 
  EEA18720.1 400 MMIGSFFFSgGLFIIGWTSD---RSIHWIAFCIGGACIGLGFFTIFQSSISYLVDVYLMlaASALAANMLMRSVLAGAFPLFANAMVTNLGIGWACSVL 495
                 44444444444444444443...4444555555556666666666655555554433330033333333344445555555555566666666666677 PP

                 HHHHHHHHHHHHHHS CS
    Sugar_tr 423 aglavlfiifvfffv 437
                 +++a+++i + f+f+
  EEA18720.1 496 GFIAAAMIPIPFLFY 510
                 777777777766666 PP

>> DUF4112  Domain of unknown function (DUF4112)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.3    0.0001      0.45      25      57 ..     348     379 ..     332     420 .. 0.76
   2 ?   -1.0   0.2      0.47   2.1e+03      25      53 ..     436     458 ..     413     498 .. 0.50

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.0001
     DUF4112  25 fGldpiigliPvvGdvisallslylvleakkae 57 
                  G+++++g +P++G +i++++++ +++ + + +
  EEA18720.1 348 RGWNSVVGSLPFLGILIGLFFAAIVLMWS-QTF 379
                 6********************98888777.333 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.47
     DUF4112  25 fGldpiigliPvvGdvisallslylvlea 53 
                 +      g++ ++   is+l+ +yl+l a
  EEA18720.1 436 L------GFFTIFQSSISYLVDVYLMLAA 458
                 3......3333333444444444444444 PP

>> DUF423  Protein of unknown function (DUF423)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.2      0.22   9.8e+02      32      74 ..     331     368 ..     323     387 .. 0.55
   2 ?   11.1   0.5   7.9e-05      0.35      30      84 ..     368     426 ..     366     431 .. 0.78
   3 ?   -2.1   0.4         1   4.5e+03      27      52 ..     453     472 ..     441     495 .. 0.61

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.22
      DUF423  32 alallavallaskaaasrllklagllflaGivlFSgslyllal 74 
                 a++ l +a++       +  ++ g+  ++G + F g l  l +
  EEA18720.1 331 AIIYLTIAIFP-----IEFEEVRGWNSVVGSLPFLGILIGLFF 368
                 55555555543.....344455555555555555555544443 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 7.9e-05
      DUF423  30 yhalallavalla....skaaasrllklagllflaGivlFSgslyllaltgkkvlgait 84 
                 + a++l+  +++       + ++ ++++  + +++G ++FSg l+++  t+++++ +i+
  EEA18720.1 368 FAAIVLMWSQTFYvkrlIANNNKPVPEARLVSMMIGSFFFSGGLFIIGWTSDRSIHWIA 426
                 5566666666555666655677888899999*********************9999886 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 1
      DUF423  27 Yqlyhalallavallaskaaasrllk 52 
                 Y ++ a al a  l+ +     ++l 
  EEA18720.1 453 YLMLAASALAANMLM-R-----SVLA 472
                 556666666555555.2.....2222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (527 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       784  (0.043728); expected 358.6 (0.02)
Passed bias filter:                      360  (0.0200792); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.59u 0.30s 00:00:00.88 Elapsed: 00:00:00.44
# Mc/sec: 3583.47
//
Query:       EEA18721.1  [L=408]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.1e-09   35.3   2.5    9.1e-09   35.3   2.5    2.0  2  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.3   2.5   5.1e-13   9.1e-09       2      36 ..       8      40 ..       7      43 .. 0.90
   2 ?   -2.8   1.3      0.42   7.5e+03       3       7 ..     264     268 ..     259     271 .. 0.74

  Alignments for each domain:
  == domain 1  score: 35.3 bits;  conditional E-value: 5.1e-13
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfyses 36
                aCdnC++ Kv+C+++ P C+ C   ++ C  +s s
  EEA18721.1  8 ACDNCHRAKVRCSGQLP-CQGCLNTGALCF-FSLS 40
                9****************.***********8.6655 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.42
                 -HHHH CS
     Zn_clus   3 CdnCr 7  
                 C++Cr
  EEA18721.1 264 CTSCR 268
                 66676 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (408 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       894  (0.0498633); expected 358.6 (0.02)
Passed bias filter:                      508  (0.028334); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.41
# Mc/sec: 2993.35
//
Query:       EEA18722.1  [L=226]
Description: hypothetical protein PMAA_010050 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (226 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       405  (0.0225891); expected 358.6 (0.02)
Passed bias filter:                      334  (0.018629); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 1610.57
//
Query:       EEA18723.1  [L=814]
Description: actin cytoskeleton organization protein App1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      9e-34  115.8   0.0    2.4e-33  114.4   0.0    1.8  1  DUF2183   Uncharacterized conserved protein (DUF2183)


Domain annotation for each model (and alignments):
>> DUF2183  Uncharacterized conserved protein (DUF2183)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.4   0.0   1.3e-37   2.4e-33       1      99 []     378     474 ..     378     474 .. 0.97

  Alignments for each domain:
  == domain 1  score: 114.4 bits;  conditional E-value: 1.3e-37
     DUF2183   1 ffYvSaspwnlyplleeFleenglPkgslllrdlsltlksllkekstaehKraeiekiletfperkfiliGDsgqkdpeiYaeiakefpeqikaiyIRd 99 
                 ++YvS+spw+lyp+l+ F++ +glP+gs++l+++s  l+++++   tae+Kr +++ki+++fp+rkfil+GDsg++d+e+Y+e+++++p++i+ ++IRd
  EEA18723.1 378 IHYVSNSPWQLYPQLKLFFKIAGLPNGSFHLKQYSGMLQGIFE--PTAERKRMSLDKIMRDFPKRKFILVGDSGEADLEVYTELVQQNPGKILGVFIRD 474
                 69*********************************99999997..59***************************************************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (814 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       739  (0.0412181); expected 358.6 (0.02)
Passed bias filter:                      480  (0.0267723); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.26s 00:00:00.91 Elapsed: 00:00:00.41
# Mc/sec: 6015.07
//
Query:       EEA18724.1  [L=85]
Description: hypothetical protein PMAA_010070 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (85 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       837  (0.0466841); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.41u 0.28s 00:00:00.69 Elapsed: 00:00:00.44
# Mc/sec: 583.11
//
Query:       EEA18725.1  [L=231]
Description: hypothetical protein PMAA_010080 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
      0.026   14.7   2.9      0.026   14.7   2.9    2.9  3  DUF4611         Domain of unknown function (DUF4611)
       0.53    8.3   4.3        0.7    7.9   4.3    1.1  1  Sporozoite_P67  Sporozoite P67 surface antigen


Domain annotation for each model (and alignments):
>> DUF4611  Domain of unknown function (DUF4611)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   2.9   2.9e-06     0.026      36      81 ..      52      95 ..      45     108 .. 0.75
   2 ?   -0.7   1.2      0.18   1.6e+03      65      79 ..     121     135 ..     116     154 .. 0.49
   3 ?   -2.5   0.0      0.69   6.2e+03      77      91 ..     146     160 ..     141     167 .. 0.75

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 2.9e-06
     DUF4611 36 aqlreevsellstlveqeaqddvaaagdeeeegededdeeeeknik 81
                a +r+ v+++  +l +  a+dd +++++++e++++e ++eee   +
  EEA18725.1 52 ASMRTPVPAVVVDLRKPTASDDSDNNDSDDEDDDEEGNAEEEI--T 95
                57999*********99999998887777777766666666643..2 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.18
     DUF4611  65 eeegededdeeeekn 79 
                 eee+e+e + e   n
  EEA18725.1 121 EEEEEEEAQGEYRYN 135
                 222222222333334 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 0.69
     DUF4611  77 ekniknktksdePpa 91 
                 +++ik +++s++P+ 
  EEA18725.1 146 TRTIKPTKQSSQPSQ 160
                 567788888888874 PP

>> Sporozoite_P67  Sporozoite P67 surface antigen
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   4.3   7.9e-05       0.7      74     166 ..      39     161 ..      33     174 .. 0.63

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 7.9e-05
  Sporozoite_P67  74 ktvptpvseeiitrsfqepvsqe.selqsdteineddkGskedseeddd.................................eeeeednkstssk 134
                     k + +pv  +  + s+++pv    ++l++ t  +++d+ +++d+++d++                                 eeeee++     +
      EEA18725.1  39 KKLRSPVRSNEWSASMRTPVPAVvVDLRKPTASDDSDNNDSDDEDDDEEgnaeeeiteldsstpkasqypyrprgplptfanEEEEEEEAQGEYR 133
                     55667887888888888888654156666665555544444444444447777888888899999999999999999999743333333333333 PP

  Sporozoite_P67 135 dgkgskkaqpgvssssgsttsqtdlstklsqt 166
                      +   +k     s ss+ t  +t++s++ sq+
      EEA18725.1 134 YNYHCRKN----SVSSTRTIKPTKQSSQPSQA 161
                     33333332....55677777777777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (231 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1148  (0.0640303); expected 358.6 (0.02)
Passed bias filter:                      477  (0.0266049); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 1556.83
//
Query:       EEA18726.1  [L=246]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      8e-06   25.9  10.8    1.2e-05   25.4  10.8    1.2  1  MARVEL    Membrane-associating domain


Domain annotation for each model (and alignments):
>> MARVEL  Membrane-associating domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.4  10.8   6.6e-10   1.2e-05       7     142 ..      13     171 ..       9     173 .. 0.82

  Alignments for each domain:
  == domain 1  score: 25.4 bits;  conditional E-value: 6.6e-10
      MARVEL   7 gilrilqlvfaiiilgliasliakldqllgspssalnfavfvavfsflyalfllvlylfknsaftsilwplidlivdalaallwlvafialaaglrdis 105
                   +r+lq++++++ lg+ ++++   + l ++  +++ +  +v +++ +++l++l++ ++    +t+ +   +  +v   + + ++ + +a+a+ +rd  
  EEA18726.1  13 NGIRVLQFLAGVVMLGIFSYFL---AVLTNHHLPIATWIRAVEGIAGAATLYTLLASIL----TTCLAGHTFFGAVGMFLDVCFVGGMVAIAVMTRDGT 104
                 689*******************...7799***************************995....555555555555555555555566666666666533 PP

      MARVEL 106 ca.............................fe.snqysasltvrcgqaqaavafgflavllfaasa 142
                 ++                             +    +y ++l+ +c+ +++  a + ++++lf++s+
  EEA18726.1 105 QTcsgyvttplgngasdskasgygsdgfgfgSGeTITYLPNLGLACRLEKTVFAVSIISIFLFLVSV 171
                 33559*****************999998765116799***************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (246 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       704  (0.039266); expected 358.6 (0.02)
Passed bias filter:                      343  (0.019131); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.25s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 1755.60
//
Query:       EEA18727.1  [L=605]
Description: flavin-binding monooxygenase-like protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      3e-16   59.0   0.0    6.6e-16   57.8   0.0    1.5  2  FMO-like       Flavin-binding monooxygenase-like
    1.4e-12   47.5   0.0    3.6e-11   42.9   0.0    2.6  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
      3e-12   46.3   0.0    3.3e-10   39.6   0.0    2.8  3  K_oxygenase    L-lysine 6-monooxygenase (NADPH-requiring)
    5.4e-09   36.2   0.0    1.5e-07   31.5   0.0    2.5  2  NAD_binding_9  FAD-NAD(P)-binding
    2.6e-06   27.3   0.1     0.0073   15.9   0.3    3.1  3  DAO            FAD dependent oxidoreductase
    5.7e-06   25.8   0.0    0.00012   21.5   0.0    2.1  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    1.1e-05   25.5   0.0    4.1e-05   23.7   0.0    2.0  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
    0.00064   19.0   0.1     0.0023   17.2   0.0    1.8  2  Thi4           Thi4 family
  ------ inclusion threshold ------
      0.019   14.0   0.0      0.031   13.3   0.0    1.3  1  Lycopene_cycl  Lycopene cyclase protein
      0.027   13.8   0.0      0.041   13.2   0.0    1.3  1  FAD_oxidored   FAD dependent oxidoreductase
      0.033   13.7   0.1        0.1   12.1   0.1    1.8  2  NIR_SIR        Nitrite and sulphite reductase 4Fe-4S domain
      0.053   12.6   0.4        6.4    5.7   0.4    2.2  2  FAD_binding_2  FAD binding domain
      0.098   11.3   0.4         11    4.5   0.0    2.5  3  HI0933_like    HI0933-like protein
       0.12   10.9   0.1        1.5    7.3   0.0    2.1  2  Mqo            Malate:quinone oxidoreductase (Mqo)


Domain annotation for each model (and alignments):
>> FMO-like  Flavin-binding monooxygenase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.8   0.0   5.2e-19   6.6e-16       5     206 ..      11     224 ..       8     266 .. 0.83
   2 ?   -4.2   0.0       3.2   4.1e+03     351     390 ..     460     501 ..     451     504 .. 0.63

  Alignments for each domain:
  == domain 1  score: 57.8 bits;  conditional E-value: 5.2e-19
    FMO-like   5 aviGaGvsGlasikccl...eegleptcfersddiGGlwrfkenveeGrasiyksvvsnsskemscfsdfplpedy.....p.nflhnsklleylklfa 94 
                  ++G+G+sGl  +++ +   +  l  + +e    iGG+w         + ++y  + +n       fsdfp+  +      p ++++ +++ +yl+++ 
  EEA18727.1  11 VIVGGGISGLCVLRTIItlsKSSLSIALLENQPSIGGVWA--------QERLYTDLKTNHVLGSYEFSDFPMRSHIssdvkPkEHIPGKEVHDYLEAYV 101
                 69**********9998733347899999***********6........4589********************9987222222357778899******** PP

    FMO-like  95 kefdllkyiqfkttvcsvkkrpdfstsGqwevvtekegkkesavfda..vmvctGhhvnphlplesfpGiekfkGqyfhsrdyk..epevfk....... 182
                 +ef l  yi++  +v sv  r d   +  wev  e      +a   a  ++v tG   +p++p   fp  e fk  +fh  d    epe f+       
  EEA18727.1 102 DEFALRGYIRLGKKVESVVERRDGE-ASSWEVEVEDLSTSIKATIRAkkLIVATGQTSQPYFPERLFPDQETFKRPMFHCVDLHkyEPELFDksqnapq 199
                 *********************9975.557**99988777777766653489*****************************9865236999965555555 PP

    FMO-like 183 .gkrvlviGlGnsggdiavelsrta 206
                  gkr+ v G   s+ d a  +++t 
  EEA18727.1 200 gGKRITVFGSAKSAFDAAYTIAETY 224
                 58**************999888764 PP

  == domain 2  score: -4.2 bits;  conditional E-value: 3.2
    FMO-like 351 lykkvfp..anl.ekptlaiiGliqplGsilptvelqarwavr 390
                 ly+ + p  ++l    ++a +G+  +  s + +++ qa w++ 
  EEA18727.1 460 LYRFLIPctPRLaSSRSIAFLGMATTA-STMLITQAQALWIAA 501
                 566665522233134568888887655.555677889999875 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.9   0.0   2.8e-14   3.6e-11       1     198 [.      11     236 ..      11     262 .. 0.72
   2 ?    1.1   0.0      0.15   1.9e+02     213     270 ..     338     388 ..     320     408 .. 0.72

  Alignments for each domain:
  == domain 1  score: 42.9 bits;  conditional E-value: 2.8e-14
  Pyr_redox_3   1 iIiGaGPaGl...aaaielkkagledylilEkg.nignsiyrypkemtfispsftsekleipdlnaiseetspafslkeeklsrkealeYlrevaksf 94 
                  +I+G+G  Gl    + i+l k+ l ++  lE + +ig  + + +  + + + +    + e+ d+++ s+ +s      +e++ +ke+ +Yl++++++f
   EEA18727.1  11 VIVGGGISGLcvlRTIITLSKSSL-SIALLENQpSIGGVWAQERLYTDLKT-NHVLGSYEFSDFPMRSHISSD--VKPKEHIPGKEVHDYLEAYVDEF 104
                  79****999722256799999999.799****9999999998777777755.557777899998887766654..23479999*************** PP

  Pyr_redox_3  95 elp..iklfeeVesvkk....edegfeve.....ts.ketyeAkkviiAtGefdkPnklnipGeek........lvk..hyskvkefhkya.....gq 165
                   l+  i+l ++Vesv +    e+++ eve     ts k+t++Akk+i+AtG+ ++P++++  ++++        +++  h+++ + f+k +     g+
   EEA18727.1 105 ALRgyIRLGKKVESVVErrdgEASSWEVEvedlsTSiKATIRAKKLIVATGQTSQPYFPERLFPDQetfkrpmfHCVdlHKYEPELFDKSQnapqgGK 202
                  **877*********9873322234466652222244367*******************9976666433322232333323443333333322222379 PP

  Pyr_redox_3 166 kvvViGgknSavDaAlelvrk.gaeVtvvtrgse 198
                  +++V G   Sa+DaA+ ++++ +  V +++r s 
   EEA18727.1 203 RITVFGSAKSAFDAAYTIAETyNTPVDMIIRASG 236
                  9******************987999*****9875 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.15
  Pyr_redox_3 213 dienrleelvkeekikvlfnaevkeikekeeeykvktedgkkvevkddvvlatGykpd 270
                  +++n + elv+e+k+kv+   +v++++e    ++++t++   v ++d +v +tG++ +
   EEA18727.1 338 YNRNFF-ELVREGKVKVHIA-NVERLSEG--AVHLSTSE---VLESDGIVCCTGWRTT 388
                  555555.6788899999887.88888864..44555554...5666888888998765 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0     0.046        59       3      38 ..       8      44 ..       2      58 .. 0.58
   2 !   39.6   0.0   2.6e-13   3.3e-10      91     229 ..      86     238 ..      80     246 .. 0.87
   3 ?   -0.4   0.0       0.4   5.1e+02     324     341 ..     369     386 ..     340     387 .. 0.81

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.046
  K_oxygenase  3 lDligiGiGpsnLsLailleevk.kelkalflerqpe 38
                 lDl+++G G s L +  ++   + + l++  le+qp+
   EEA18727.1  8 LDLVIVGGGISGLCVLRTIITLSkSSLSIALLENQPS 44
                 5666666666666554333332223455556665554 PP

  == domain 2  score: 39.6 bits;  conditional E-value: 2.6e-13
  K_oxygenase  91 flpsRkefedYlrWvasqle..eqvrfgeeveevepdeeeeeelltveskd.aegeeeelearnlvlgvG..tepkiPevlekle..gkervvHssey 181
                  ++++ ke +dYl+  ++++     +r g++ve+v  +++ e + ++ve++d ++  + +++a++l++++G  ++p+ Pe l + +   k  ++H  ++
   EEA18727.1  86 EHIPGKEVHDYLEAYVDEFAlrGYIRLGKKVESVVERRDGEASSWEVEVEDlSTSIKATIRAKKLIVATGqtSQPYFPERLFPDQetFKRPMFHCVDL 183
                  67788999*********99844669***********999877*********999999*************8779*****986655344689****999 PP

  K_oxygenase 182 lerkee........llakkriaVvGsGqSaaeifedllrrqkkvelklvtrseale 229
                   + ++e         + +kri+V Gs +Sa + ++ ++++++ + +++++r+++  
   EEA18727.1 184 HKYEPElfdksqnaPQGGKRITVFGSAKSAFDAAYTIAETYN-TPVDMIIRASGHG 238
                  999988999998889999******************999987.8999999988765 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 0.4
  K_oxygenase 324 geeetlevdavvlATGYr 341
                   ++e+le+d +v++TG+r
   EEA18727.1 369 STSEVLESDGIVCCTGWR 386
                  467899**********98 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.5   0.0   1.2e-10   1.5e-07       1     155 [.      11     156 ..      11     157 .. 0.77
   2 ?    1.8   0.0      0.17   2.2e+02     115     154 ..     349     384 ..     335     386 .. 0.77

  Alignments for each domain:
  == domain 1  score: 31.5 bits;  conditional E-value: 1.2e-10
  NAD_binding_9   1 aivGaGprGlavlerLlarakkkspleitlfdpsepgagrvwrtdqseelllNvpasemslftddpptfaeWlrergaleeaeeldpddfvpRaly 96 
                    +ivG+G++Gl+vl+ ++  +  ks+l+i l +++++  g+vw +++   l + ++++++      + +f ++  + +      +++p++++p + +
     EEA18727.1  11 VIVGGGISGLCVLRTIITLS--KSSLSIALLENQPSI-GGVWAQER---LYTDLKTNHVLG----SYEFSDFPMRSHI---SSDVKPKEHIPGKEV 93 
                    7******************7..**************9.9*****94...566666666553....4679999777774...3589*********** PP

  NAD_binding_9  97 GrYlrdlfeellarlpegvtvevhraevvdleeradg.qavll.....adgaslaadaVvLAlGh 155
                     +Yl+++++e++ r    +++    ++vv+ ++ +++ ++v       + +a+++a+++++A+G+
     EEA18727.1  94 HDYLEAYVDEFALRG--YIRLGKKVESVVERRDGEASsWEVEVedlstSIKATIRAKKLIVATGQ 156
                    ***********9666..5677766666666666554434555511221344679*********97 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.17
  NAD_binding_9 115 vtvevhraevvdleeradgqavlladgaslaadaVvLAlG 154
                     +v+vh a+v++l+e     av+l++ + l+ d +v ++G
     EEA18727.1 349 GKVKVHIANVERLSEG----AVHLSTSEVLESDGIVCCTG 384
                    3678888888888755....68999999********9999 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.3   5.7e-06    0.0073       1      35 [.       9      47 ..       9      51 .. 0.83
   2 !    5.9   0.0    0.0064       8.2     146     208 ..      94     164 ..      91     196 .. 0.70
   3 ?    0.9   0.0      0.22   2.8e+02     149     205 ..     339     388 ..     311     426 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 5.7e-06
                EEEEECTSHHHHHHHHHHHHTT.....EEEEESSSSTTSS CS
         DAO  1 dvviiGGGiiGlstAyeLarrg.....Vtllekgdiagsg 35
                d+vi+GGGi Gl++ +   +       ++lle ++ +g g
  EEA18727.1  9 DLVIVGGGISGLCVLRTIITLSksslsIALLENQPSIG-G 47
                89**************99543224699******99888.4 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0064
                 HHHHHHHHHHHHHTT-EEEESECEEEE.EEEE..TCEEEEE...EECT.EEEEEEEEEEE--GGGHH.HH.H CS
         DAO 146 akltaalaraaealGveilegtevtgl.eeed..gkvwgve...rttp.gendaadavVnaaGawsd.ll.g 208
                 + ++ a+ ++++ + + i++g +v+++ e++d     w+ve     t+  ++ +a+++++a+G  s+  + +
  EEA18727.1  94 HDYLEAYVDEFALR-GYIRLGKKVESVvERRDgeASSWEVEvedLSTSiKATIRAKKLIVATGQTSQpYFpE 164
                 67899999999766.6799999****6477776766688877653343333323466******777665543 PP

  == domain 3  score: 0.9 bits;  conditional E-value: 0.22
                 HHHHHHHHHHTT-EEEESECEEEEEEEETCEEEEEEECTEEEEEEEEEEE--GGGHH CS
         DAO 149 taalaraaealGveilegtevtgleeedgkvwgverttpgendaadavVnaaGawsd 205
                  + + + ++++ v+++   +v++l+e   +++++   t++  ++ d +V ++G  ++
  EEA18727.1 339 NRNFFELVREGKVKVHIA-NVERLSE---GAVHL--STSEVLES-DGIVCCTGWRTT 388
                 556667778888888887.9999965...35666..44343355.88******7665 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.0   9.1e-08   0.00012       2     164 ..       9     223 ..       8     258 .. 0.61
   2 ?    2.1   0.0     0.074        94     198     243 ..     351     391 ..     336     408 .. 0.73

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 9.1e-08
                  SEEEE--SHHHH...HHHHHHHHHTS-EEEEE.............TTHCHHHCSHHHHCHHHHHHHHHHHHH.......................... CS
                  xxxxxxxxxxxx...xxxxxxxxxxxxxxxxx.............xxxxxxxxxxxxxxxxxxxxxxxxxxx.......................... RF
  Pyr_redox_2   2 dvvviGgGpAGl...aaaltlaqagakvtlve.............legtclnggcllskallgvaedaeias.......................... 57 
                  d+v++GgG+ Gl   ++ +tl+++++ ++l+e             l + + ++++l s+++                                     
   EEA18727.1   9 DLVIVGGGISGLcvlRTIITLSKSSLSIALLEnqpsiggvwaqerLYTDLKTNHVLGSYEFS---------Dfpmrshissdvkpkehipgkevhdyl 97 
                  79*********633377888888********7667744444433433334444444444444.........2555555556**999999999888888 PP

                  .............HHHHCHHHHCCCCHCCTCEEEEESCEEEEETEEECTCEEEEEESEEEE---EEE-BCTCTTC.........TTBEECCSECHHHH CS
                  .............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxx RF
  Pyr_redox_2  58 .............evvkklnqgielllgeevvkidpgkkkvklekkkegdeekiaydklvlAtGssprdlgipGv........aenvgklvrtldsae 134
                               +  kk+++ +e++ g e+        +v++e+++++ + +i ++kl++AtG ++  +  p          +       r++ ++ 
   EEA18727.1  98 eayvdefalrgyiRLGKKVESVVERRDG-EA----SS-WEVEVEDLSTSIKATIRAKKLIVATGQTS-QPYFPERlfpdqetfK-------RPMFHCV 181
                  8555444443333111122222222222.11....22.25666666668999************533.3333333332223332.......4444444 PP

                  HHCCSS-T............SEEEEES-SHHHHHHHHHHHHH CS
                  xxxxxxxx............xxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 135 alklkllp............krivvvGgGyiGvElAaalakl 164
                   l++ + +            kri+v G+   + + A ++a+ 
   EEA18727.1 182 DLHKYEPElfdksqnapqggKRITVFGSAKSAFDAAYTIAET 223
                  444444444445556889999999999999999999987665 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.074
                  EEEEESCEEEEEEETTEEEEEEETTSCEEEESEEEE-S-EEES-HH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 198 vevklgtsvkeidgngeklevvledgeeidadlvvvavGvrpstel 243
                  v+v+  ++v+++ +      v+l++ e+++ d +v ++G r  +++
   EEA18727.1 351 VKVH-IANVERLSEGA----VHLSTSEVLESDGIVCCTGWRTTPSI 391
                  4555.44554444222....89999999***********9988766 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.7   0.0   3.2e-08   4.1e-05       1      41 [.      12      56 ..      12      84 .. 0.80

  Alignments for each domain:
  == domain 1  score: 23.7 bits;  conditional E-value: 3.2e-08
                   EE--SHHHHHHHHH...HHCCTEEEEEE-SSSSSSGGG-EECE.T CS
  NAD_binding_8  1 IvGaGlsGlvaAyl...LakagfdvlllekrdrlGGraasyev.p 41
                   IvG+G+sGl+  ++   L+k  +++ lle+++++GG +a +++  
     EEA18727.1 12 IVGGGISGLCVLRTiitLSKSSLSIALLENQPSIGGVWAQERLyT 56
                   9*********98775557899****************99998763 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   1.8e-06    0.0023      16      61 ..       6      52 ..       1      61 [. 0.79
   2 ?   -1.5   0.0      0.96   1.2e+03      20      47 ..     204     231 ..     202     243 .. 0.76

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 1.8e-06
                TEEEEEEE--SHHHHHHHHHHHHC..TTS-EEEEESSSS--TTTTTTS CS
        Thi4 16 aesDvvivGaGssGLtaayylakk..pdlkvailersvspGGGawlGG 61
                 e D+vivG+G sGL   +++ +     l +a+le++ s+GG +w   
  EEA18727.1  6 EELDLVIVGGGISGLCVLRTIITLskSSLSIALLENQPSIGG-VWAQE 52
                589************998876432235************975.77655 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.96
                 EEEE--SHHHHHHHHHHHHCTTS-EEEE CS
        Thi4  20 vvivGaGssGLtaayylakkpdlkvail 47 
                 + + G+  s   aay++a+  +  v ++
  EEA18727.1 204 ITVFGSAKSAFDAAYTIAETYNTPVDMI 231
                 6789999999*******99866666544 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   2.4e-05     0.031       1     145 [.       9     160 ..       9     188 .. 0.67

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 2.4e-05
  Lycopene_cycl   1 DvvviGaGpAglslAarl.teakpglkvvlieaspsl..lfpnnyvWsdefedlgaleecvehsWsgtivylddgkkillgraYgrvsskrlkeel 93 
                    D+v++G+G  gl +   + t +k  l++ l+e  ps+  ++++++ + d +++   l +      ++   ++  + k +   + + v+ + l++ +
     EEA18727.1   9 DLVIVGGGISGLCVLRTIiTLSKSSLSIALLENQPSIggVWAQERLYTDLKTNHV-LGSYEFSDFPMRS-HISSDVKPKEHIPGKEVH-DYLEAYV 101
                    9**********9888776589***********99988335666666666555555.4444444444333.333333333334666665.5566666 PP

  Lycopene_cycl  94 lerlvengvklleakvesveeeeagesl...vvleggr.....kirarlvvdarglaslk 145
                     e     g ++l  kvesv+e  +ge +   v +e+       +ira+  ++a+g  s++
     EEA18727.1 102 DEFA-LRGYIRLGKKVESVVERRDGEASsweVEVEDLStsikaTIRAKKLIVATGQTSQP 160
                    5544.4888888888888888888554322255555445566688888888888866554 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   3.2e-05     0.041       1     144 [.       9     155 ..       9     158 .. 0.59

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 3.2e-05
  FAD_oxidored   1 DvvVvGGgpaGva...AAiaAaraGakvlLveergvlGGlltsglvatdignkaeeqvvtg.iareflerlrqrggarlkkrskw.ntfepevakav 92 
                   D+v+vGGg++G++     i+  ++  + +L+e+++ +GG  +++ + td++++   +v +   + +f  r +   ++    + k+ ++   + +   
    EEA18727.1   9 DLVIVGGGISGLCvlrTIITLSKSSLSIALLENQPSIGGVWAQERLYTDLKTN---HVLGSyEFSDFPMRSHI--SS----DVKPkEHIPGKEVHDY 96 
                   99*********995556799999**************************9977...44444134455444422..11....1111112222223333 PP

  FAD_oxidored  93 leemlae..agvtvllntrlveveke.gkr..iesvtveske.g.rktirAkvfiDATg 144
                   le+ ++e   +  + l++++++v+ + +++   ++v+ve+ +   + tirAk  i ATg
    EEA18727.1  97 LEAYVDEfaLRGYIRLGKKVESVVERrDGEasSWEVEVEDLStSiKATIRAKKLIVATG 155
                   33333221112345566666666553222224666666666655677777777776666 PP

>> NIR_SIR  Nitrite and sulphite reductase 4Fe-4S domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       3.1     4e+03      28      57 ..      56      85 ..      47     109 .. 0.65
   2 ?   12.1   0.1   8.2e-05       0.1     123     153 ..     560     590 ..     553     595 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 3.1
                HHHHHHHHCTCCCCTSSSS-BEEEEESSTC CS
                xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
     NIR_SIR 28 akaiedelepeygetylPrKfKiavsgcpn 57
                +   ++++ + y+++++P +  i+ ++ p+
  EEA18727.1 56 TDLKTNHVLGSYEFSDFPMRSHISSDVKPK 85
                555556777777777777776666655554 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 8.2e-05
                 HHS-CSSGGG-SHHHHHHHHHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
     NIR_SIR 123 dhgdrknrkkeRlkylverlGvekFrekvee 153
                 d g r++rk  +lk++ve +Gve  r  vee
  EEA18727.1 560 DVGLRQQRKETKLKEWVEAYGVEDYRGLVEE 590
                 7899***********************9976 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.4     0.005       6.4       1      36 [.       9      47 ..       9      53 .. 0.82
   2 ?    4.7   0.0     0.011        14     131     207 ..      81     163 ..      52     179 .. 0.70

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.005
                   SEEEE--SHHHH...HHHHHHHHTTT-EEEEESSSGGGS CS
  FAD_binding_2  1 DviViGsGlAGL...aAAleaaeaGlkvavvekeqefgg 36
                   D++++G+G++GL   +  +++++  l++a++e+ ++ gg
     EEA18727.1  9 DLVIVGGGISGLcvlRTIITLSKSSLSIALLENQPSIGG 47
                   89*********7222568999999999999999998776 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.011
                    T-......HHHHHHHHHHHHHHTCT..EEEEESEEEEEEEE.CTTEEEE..EEEEETTTTCEEEEEESEEEE-----GG.... CS
  FAD_binding_2 131 darretlvtghallarlvesarkag..vdfqerteadeLiv.edgrvtG..avvenpesgrevrirakavvlatgGfgr.all 207
                    d + ++ ++g+++   l +++++ +    ++   ++++++  +dg+++   ++ve+++++ + +irak++++atg  ++  ++
     EEA18727.1  81 DVKPKEHIPGKEVHDYLEAYVDEFAlrGYIRLGKKVESVVErRDGEASSweVEVEDLSTSIKATIRAKKLIVATGQTSQpYFP 163
                    444467777777777777777777754445555677777663466666611555556999999*************9985333 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.0    0.0088        11       2      36 ..       9      46 ..       8      47 .. 0.82
   2 ?    4.4   0.0    0.0099        13     132     168 ..     127     160 ..      91     162 .. 0.71
   3 ?   -3.6   0.0       2.5   3.3e+03     130     169 ..     353     390 ..     348     391 .. 0.74

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.0088
                 SEEEE--SHHHHH...HHHHHHHTT--EEEE-SSSSS- CS
  HI0933_like  2 dviviGgGaAGlm...aAisaakrgkrVlllekakklg 36
                 d++++GgG +Gl    + i+++k   +++lle+++++g
   EEA18727.1  9 DLVIVGGGISGLCvlrTIITLSKSSLSIALLENQPSIG 46
                 78*********97222456669***********99987 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.0099
                  EEEEECETTE.EEEEE.TTEEEEESEEEE----SS-G CS
  HI0933_like 132 vksvekeedgkfrvktkseeeleadklvlAtGGlSiP 168
                   +s+e e +    ++t+ + +++a+kl++AtG +S P
   EEA18727.1 127 ASSWEVEVED---LSTSIKATIRAKKLIVATGQTSQP 160
                  3444443333...44445889*************998 PP

  == domain 3  score: -3.6 bits;  conditional E-value: 2.5
                  --EEEEECETTE.EEEEE.TTEEEEESEEEE----SS-GG CS
  HI0933_like 130 tevksvekeedgkfrvktkseeeleadklvlAtGGlSiPk 169
                   ++++ve+ ++g+++++t  +e le+d +v  tG    P+
   EEA18727.1 353 VHIANVERLSEGAVHLST--SEVLESDGIVCCTGWRTTPS 390
                  567777777777555555..99999999999999888776 PP

>> Mqo  Malate:quinone oxidoreductase (Mqo)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.1     0.079     1e+02       2      39 ..       7      45 ..       6      52 .. 0.81
   2 ?    7.3   0.0    0.0012       1.5     198     243 ..     110     158 ..      97     174 .. 0.82

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.079
         Mqo  2 kvdvvliGaGimsat.lgvllkelepelsievlerldkv 39
                + d+v++G+Gi     l ++++  +++lsi++le+  ++
  EEA18727.1  7 ELDLVIVGGGISGLCvLRTIITLSKSSLSIALLENQPSI 45
                689********98652777777778999***99987665 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0012
         Mqo 198 lklkhevkdlkreedgk...WkvkvkdlktgekkkvkakfvfiGaGGga 243
                 ++l+++v+++ +++dg+   W+v+v+dl+t+ k +++ak + + +G ++
  EEA18727.1 110 IRLGKKVESVVERRDGEassWEVEVEDLSTSIKATIRAKKLIVATGQTS 158
                 67788888887776654444*********************99999776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (605 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       391  (0.0218082); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.45
# Mc/sec: 4032.91
//
Query:       EEA18728.1  [L=435]
Description: plasma membrane SNARE protein (Sec9), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
       0.39   10.8   7.2       0.34   11.0   5.3    1.8  2  Ribosomal_L19e  Ribosomal protein L19e
       0.51   10.1   6.6       0.31   10.8   1.0    2.1  2  DUF1481         Protein of unknown function (DUF1481)


Domain annotation for each model (and alignments):
>> Ribosomal_L19e  Ribosomal protein L19e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       0.4   3.6e+03      50      73 ..     222     245 ..     202     260 .. 0.56
   2 ?   11.0   5.3   3.8e-05      0.34      22     107 ..     258     349 ..     248     367 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.4
                     E-------THHHHHHHHHHHTT-S CS
  Ribosomal_L19e  50 kkpkkgnsrararerkekkrkgrr 73 
                     k+ +   +r  +r+ +++ + gr+
      EEA18728.1 222 KQGDVSSTRNALRAAAQAEETGRN 245
                     333333444555555555555554 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 3.8e-05
                     E-GGGHHHHHH--S......HHHHHHHHHTTSEEE-------THHHHHHHHHHHTT-S-SGGG--S-HHHHS-HHHHHHHHHHHHHHHHHHH CS
  Ribosomal_L19e  22 ldpeeleeiaeAit......redirklikdglIikkpkkgnsrararerkekkrkgrrrgsGkrkGtkeaRlpekelWikriRalRrlLkel 107
                     ld+e++ ++a+++        +++++l k+ + ++ ++  +s+ar r+r+ek  + +r+++G r+Gt++  +++ ++  ++ R + r  +++
      EEA18728.1 258 LDTEKSLDVAASQGrlaeekARELKTLNKSMFAVHVSNPFTSNARRRDRDEKILETHRSERGTREGTRQEAFQSNQRMERTFRDIERDANKV 349
                     566666666666555555545789999999999999*********************************99999999999999887766555 PP

>> DUF1481  Protein of unknown function (DUF1481)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   1.0   3.5e-05      0.31      44     112 ..     195     265 ..     174     280 .. 0.83
   2 ?    2.1   0.4     0.015   1.4e+02      91     121 ..     357     387 ..     304     404 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 3.5e-05
     DUF1481  44 rwqegkLreikregegkkpesvqlRfdkeGevvfmqrql..dgrkeplsedqlalyqfeAkrllelskalr 112
                  +qe +L+  ++e e+ +  + ++Rf k+G+v+  +  l  + + e+  ++ la++  +++r+l++ k+l+
  EEA18728.1 195 VYQERQLTAEEEEEEEVNAVKQEIRFIKQGDVSSTRNALraAAQAEETGRNTLARLGAQSERILDTEKSLD 265
                 69999***9999999*******************9986622678889999**************9999886 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.015
     DUF1481  91 edqlalyqfeAkrllelskalragrveLvQG 121
                   + a+yqfeA++  e+ ++  +++++L+ G
  EEA18728.1 357 MSERAKYQFEADSEDEAMEDEIDNNLNLLSG 387
                 346789******************9999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (435 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1049  (0.0585086); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.31s 00:00:00.88 Elapsed: 00:00:00.49
# Mc/sec: 2691.72
//
Query:       EEA18729.1  [L=675]
Description: vacuolar sorting protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.2e-115  387.9   0.0   1.4e-115  387.7   0.0    1.0  1  Sec1      Sec1 family


Domain annotation for each model (and alignments):
>> Sec1  Sec1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  387.7   0.0  7.9e-120  1.4e-115       1     574 [.      31     655 ..      31     656 .. 0.87

  Alignments for each domain:
  == domain 1  score: 387.7 bits;  conditional E-value: 7.9e-120
                 EEEEE-HHHHHHHHTT--HHHHHTTTEEETT..T--S-.....BTTSEEEEEE-S.-HHHHHHHHHHHHSS.....-SBS-EEEEESS---...HHHHH CS
        Sec1   1 KvLvlDkelskilssvlkvsdlleegVtkieklkkrepskrealphlkaiyflrp.tkenidrlakdfisa.....rrykeyhifftprls...eslle 90 
                 K Lv+ k+l++++++++k+s l++ gV++++ l  ++++++++++++  ++++   ++  +  +a ++i++        ++++if++pr++   +s+le
  EEA18729.1  31 KNLVISKDLAGPVGLFVKFSVLQDYGVDRVFLL--ENGNLDSSQRNV--VFLVHAeKVNQVAQVA-EQIKKlrqssSVEHDISIFWVPRRTlvsDSILE 124
                 89*********************88******99..99999*******..****996666677777.667777889999********************* PP

                 ..HHHH..SG.GGGEEEEE----SEEEETTEEE-STTHHHHSTTG.....GG.......--HHHHHHHHHHHHHHH-...--EEEE-TT-HHHHHHHH. CS
        Sec1  91 ..glakadeevvkkvklkelnldfvplesdlfslnpelplsfrdlyldndnsaleeeieslldriakgLlsvllslek.kiPiirykgsaasmvakkla 186
                   g++ +d   v+   + +l++ f+ple+d++sl  el+++f dlyl++++++++          akgL++  +++++  +P+i +kg++a+++a+ l+
  EEA18729.1 125 eaGIT-GD---VN---IADLPVYFLPLEQDVLSL--ELDTAFGDLYLHKNPASIYL--------SAKGLMN--IQRRHgYFPRITGKGDNARKLADLLI 204
                 98888.89...99...88****************..999*******9888887777........*******..8883359************7777775 PP

                 .........HHHHTTT.........--SS--EEEEE-GGG-SSTTTS---BHHHHHHHHS--BTEEEEEE--SS..................SEEEEEE CS
        Sec1 187 delkekidskknfese.........ssrqrpvLiIlDRsvDlvtpllhqwTYqaliddllgglnnnnvvleeep..................keekeae 258
                 ++ +++++   +++s          +s++  +LiI+DR vD+ tpll+q+TY++lid+++g ++nn+ ++ ++                   +   +++
  EEA18729.1 205 RM-RKEVEA--EQSSGagpdygnklPSSTIEQLIIIDREVDFGTPLLTQLTYEGLIDEFVG-IQNNQADVDTSIvgpatqppqrssaptptaRPGLKRK 299
                 44.445554..222225679999999**********************************8.7555555555547899999999999999996666777 PP

                 --TT..-TTHHHHTTSBHHHHHHHHHHHHHHHHHHHHTTT...-TTHHHHHHHHHH-GGGHHHHHHHHHHHHHHHHHHHHS-HHH.HHHHHHHHHHHHS CS
        Sec1 259 lvesssDeffaelrhlnfgevgeklkkeakeyqeenekkrngakesiadlkkfvaklpelqeekkklskHtnlaeellkevkkrkldellelEqdlatg 357
                 + ++ssD++f++lr+ nf+ vg+ l+k a+++ +++ ++r++a+ ++a+l++fv++lp +q+e+++l++Htnlae+++++++++ +++ le++q+ a+g
  EEA18729.1 300 IQLDSSDPLFNQLRDTNFAIVGDILNKVARRLESDY-ETRHSAQ-TTAELREFVNRLPAYQQEHQSLKIHTNLAEDIMRQTRSDIFRKTLEVQQSNAAG 396
                 777778******************************.8999888.****************************************************97 PP

                 S--..B--..-HHHHHHHH-TTS-H.HHHHHHHHHHHH...-B.-HT--GG....GGHHHHGGGGG........---.BGGG-------.......... CS
        Sec1 358 esd.kkikekkvieeliaddeptseledklRLlllyslvegglkekelkellrelvqsalygleylktlrsleklgllkkrkgkksskkkss....... 448
                 + d + ++++  i elia+d+p   l+++lRLl+l s+  ggl++k+l+ ++re++q a yg+++l t+r+lek++ll++r ++++             
  EEA18729.1 397 T-DpSYQHSN--ISELIARDVP---LKTILRLLCLESCMSGGLRAKDLDFFKREILQ-A-YGYQHLLTFRALEKMELLQPRGSATAMLLPGAvggavag 487
                 5.66899988..**********...99************99****************.9.******************88888665555555******* PP

                 ...............---------S...TT-.----HHHHHHHHHTTT-S-TTTS-BSS-GGGS----............................... CS
        Sec1 449 ...........lklikeeedeesnydlsgvs.ryaPllvrlvealikgkklssespslskkdpsqees............................... 504
                            l+l  ee++e +++d+s v+  +aPl+vrlv+++++++   s  +   +++++   +                               
  EEA18729.1 488 tktnynylrknLRLVVEEVSEKDPNDISYVYsGFAPLSVRLVQCILQKSHMMSLIKGGFTSSAAP--Taqintsntsspgwigfediaksargstfsiv 584
                 ********9999999999999999995555555**************555555554443333333..234778888889******************** PP

                 .----------------------S-EEEEEEEEEE-HHHHHHHHHHT...TSSSEEEEEEEEE--HHHHHH CS
        Sec1 505 .ssslrsakktnsaskesaekkkkqrviVffvGGvTysEiralrllskqekknkeiiigttsilnpksfle 574
                  +++++  ++++s ++++ +   +++v ++f+GG+T++Ei+alr++++qe+ +++i+i+tt+il+++++++
  EEA18729.1 585 qKGDEKAIRARQSLTSSGGSLGHQKTVYIMFLGGITFTEIAALRYIAAQEAATRKIVICTTGILSGDRMMD 655
                 96666666677777777777778899***********************9999**************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (675 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       780  (0.0435049); expected 358.6 (0.02)
Passed bias filter:                      663  (0.0369792); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.70u 0.31s 00:00:01.01 Elapsed: 00:00:00.46
# Mc/sec: 4390.69
//
Query:       EEA18730.1  [L=421]
Description: calcium/calmodulin-dependent protein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.9e-69  234.0   0.0    2.6e-69  233.5   0.0    1.2  1  Pkinase        Protein kinase domain
    1.5e-34  119.5   0.0    2.1e-34  119.0   0.0    1.2  1  Pkinase_Tyr    Protein tyrosine kinase
    7.3e-06   25.5   0.0      1e-05   25.0   0.0    1.3  1  Kinase-like    Kinase-like
     0.0018   17.7   0.1     0.0035   16.7   0.1    1.5  1  Kdo            Lipopolysaccharide kinase (Kdo/WaaP) family
     0.0081   15.7   0.1      0.048   13.2   0.0    2.1  2  YrbL-PhoP_reg  PhoP regulatory network protein YrbL


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  233.5   0.0   7.2e-73   2.6e-69       1     264 []      23     278 ..      23     278 .. 0.94

  Alignments for each domain:
  == domain 1  score: 233.5 bits;  conditional E-value: 7.2e-73
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHSCTTB--EEEEEEESSEEEEEEE--TTEBHHHHHHHHSS--HHH CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklkhpnivrlyevfeekdelylvleyveggeladllerkgslseee 99 
                 y+  ++lG G++G V +a   + + +vAvK+i k++ + +++  v  E+++l++l+hp+iv++ ++fe+ d++y+v+e++ ggel+d++ + g ++e++
  EEA18730.1  23 YRFGRTLGAGTYGIVREAD--SPEGKVAVKIILKKSVRGNEQ-MVYDELELLQRLNHPHIVHFRDWFESRDKYYIVTELATGGELFDRICECGRFTEKD 118
                 677899************9..78999*********9999885.9******************************************************* PP

                 HHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTE...EEE-SGTTSEESSSSCS.BCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHHHHHSS CS
     Pkinase 100 akkiakqilegleylHskgiiHrDlKpeNiLidekge...lKitDFGlakelesssk.ltsfvgtseYlAPEvlkeneyskkvDvWslGvilyelltgk 194
                 a++ +kqil +++ylH+++i+HrDlKpeN+L+ + +    l ++DFG+ak lesss+ lts+ g+  Y APEv+ +++++k++D+WslGvi y+ll+g 
  EEA18730.1 119 ASQTIKQILDAVRYLHERNIVHRDLKPENLLYATAATdspLVLADFGIAKMLESSSDvLTSMAGSFGYAAPEVMLKEGHGKPADMWSLGVITYTLLCGY 217
                 *********************************6555688***************999***************************************** PP

                 -STTTSSHHHHHHHHHHTHHHHHHHCTSHH...HHHTTS-HHHHHHHHHHT-SSGCCSTTHHHHHTSGGG CS
     Pkinase 195 ppfsgekgkekvekeldqlekilkilgetkeklpeaseiseeakdllkkllkkdpkkRltaeellqhpyl 264
                  pf++e+  ++  +e+++        g+++++ + ++++se+akd+++ ll+ d++kR taee+l h++l
  EEA18730.1 218 SPFRSENM-SDLIEECRH--------GKVQFHERYWRDVSEDAKDFINTLLTADQTKRATAEEALTHRWL 278
                 ****4444.445555555........5889999************************************7 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.0   0.0     6e-38   2.1e-34       2     254 ..      24     271 ..      23     275 .. 0.90

  Alignments for each domain:
  == domain 1  score: 119.0 bits;  conditional E-value: 6e-38
                  EEEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHTCTTT CS
  Pkinase_Tyr   2 elgkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkklkhpnivkllgvctkeepllivteyvkgGdLlkfLrkkekek 99 
                  ++g++lG+G++G V e+         e kVavK++ +++ + +++++++e++++++l+hp+iv++  +  ++++++ivte+++gG+L + + +    +
   EEA18730.1  24 RFGRTLGAGTYGIVREADSP------EGKVAVKIILKKSVRGNEQMVYDELELLQRLNHPHIVHFRDWFESRDKYYIVTELATGGELFDRICEC--GR 113
                  5789************9988......99*******999999999************************************************98..9* PP

                  SBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEE...TTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSEEEHHHHHHHHHHH CS
  Pkinase_Tyr 100 ltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlse...nkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekkftsksDvWsfGvl 194
                  +t kd  + + q+ ++++yL+++++vHrdl   N L ++   ++   ++DfG+a+ +  +++  + ++   ++ + apE++ ++   + +D+Ws Gv+
   EEA18730.1 114 FTEKDASQTIKQILDAVRYLHERNIVHRDLKPENLLYATaatDSPLVLADFGIAKML--ESSSDVLTSMAGSFGYAAPEVMLKEGHGKPADMWSLGVI 209
                  ************************************99856577899*********9..445555667778899************************ PP

                  HHHHHTTSSGTTTTSHHHHHHHHHHTTEES-BB...TTSBHHHHHHHHHHT-SSGGGS--HHH CS
  Pkinase_Tyr 195 lwEiftlgespypglkneevleklkegkrlekp...ekcpeelyelmkkcweedpeeRptfse 254
                  ++ +++ g sp+++ + ++++e  ++gk   +    ++++e+ ++++++ +++d+++R+t +e
   EEA18730.1 210 TYTLLC-GYSPFRSENMSDLIEECRHGKVQFHErywRDVSEDAKDFINTLLTADQTKRATAEE 271
                  *****9.*****************998875544111456778888899999999999988765 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.0   0.0   2.8e-09     1e-05     141     288 .]     116     266 ..      54     266 .. 0.75

  Alignments for each domain:
  == domain 1  score: 25.0 bits;  conditional E-value: 2.8e-09
  Kinase-like 141 letiarlllTlqlirlaanLqakglvhgkftvdnlllde...kgglmlggft..aLvragtkvvlseve.kgfaPpEllgsrggytrknktkmthkld 232
                  ++++++ +   q++  + +L+++ +vh +++++nll+     + +l+l +f+  ++      v  s+    g+a pE++ + g            + d
   EEA18730.1 116 EKDASQTI--KQILDAVRYLHERNIVHRDLKPENLLYATaatDSPLVLADFGiaKMLESSSDVLTSMAGsFGYAAPEVMLKEGH---------GKPAD 202
                  44444443..37889999*******************75222789*****982234444444444666678********99666.........4589* PP

  Kinase-like 233 aWqlGlviyriwclklPlt.lateeakeew.......kfklckkipekvkaLlkkfLqlsqedR 288
                   W lG+  y + c + P+  +  ++ +ee        + +  + ++e  k  ++ +L  +q +R
   EEA18730.1 203 MWSLGVITYTLLCGYSPFRsENMSDLIEECrhgkvqfHERYWRDVSEDAKDFINTLLTADQTKR 266
                  *****************96245566777765555522222334677777777777777777666 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.1   9.8e-07    0.0035     106     166 ..     106     164 ..      65     169 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 9.8e-07
         Kdo 106 edllakwaelaeelkrallkavgrliaklhragvnHadlyaknillqqeeeeeaeiwliDl 166
                 + +++   ++ e+   +++k++  +++ lh++++ H+dl + n+l  +++  +  ++l D+
  EEA18730.1 106 DRICE-CGRFTEKDASQTIKQILDAVRYLHERNIVHRDLKPENLLYATAA-TDSPLVLADF 164
                 44444.345778888999****************************9997.7888888887 PP

>> YrbL-PhoP_reg  PhoP regulatory network protein YrbL
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.2   0.0   1.3e-05     0.048     121     169 ..     119     165 ..      98     177 .. 0.77
   2 ?   -0.8   0.0      0.25   8.9e+02      52      81 ..     282     311 ..     256     314 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.3e-05
  YrbL-PhoP_reg 121 taelkeaLdefleelldnhivtndlsakNivvkknsegeeelvlvDGlG 169
                    + +  +++ + +++l + +iv +dl+++N+++++ +++   lvl D +G
     EEA18730.1 119 ASQTIKQILDAVRYLHERNIVHRDLKPENLLYATAATDS-PLVLAD-FG 165
                    3355666667789********************999988.788877.55 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.25
  YrbL-PhoP_reg  52 ekkykqilrElkeyvqlsklreeidnspla 81 
                    +  + + l E+k+y+ ++klr+ i+ ++la
     EEA18730.1 282 TASDHNLLPEIKAYMARAKLRRGIEIIKLA 311
                    444566788*********999999887775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (421 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       922  (0.0514251); expected 358.6 (0.02)
Passed bias filter:                      545  (0.0303977); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 2750.14
//
Query:       EEA18731.1  [L=183]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.016   15.3   0.0      0.031   14.3   0.0    1.4  1  DUF1757   Protein of unknown function (DUF1757)
      0.047   13.9   0.5          3    8.1   0.0    2.5  2  DUF3493   Low psii accumulation1 / Rep27
       0.21   10.8   0.0       0.29   10.4   0.0    1.1  1  Lipase    Lipase


Domain annotation for each model (and alignments):
>> DUF1757  Protein of unknown function (DUF1757)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   5.2e-06     0.031      17     123 ..      14     133 ..       8     145 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 5.2e-06
     DUF1757  17 dipspkvElaihvtfksvqllallGgvilgPivrlllkkk...............rnsqkiirsavkkgqggallglvvgPvltllrlkdlseeelydr 100
                 d p++k+ l +hv  +  ++++++G  +    ++l+++++                +++ i++ +   +    l+g+ ++ vl  +r+ +++e e +dr
  EEA18731.1  14 DQPYAKTLLYVHVFHRGFEAGGVIG--LFYANYKLYKHRQqlkltppqqaalggvGKNAGIRNIFYPTMARASLIGAGASMVLLTARMWGAEEVEWQDR 110
                 56999999*****************..4555677777766789**********98777889999999999999************************** PP

     DUF1757 101 cYrlRfnkeqlrvDRtavvlaav 123
                  +rl  n+ q+  D  a v a +
  EEA18731.1 111 SWRLLENEGQVMHDLYADVGAGI 133
                 ***********999855444433 PP

>> DUF3493  Low psii accumulation1 / Rep27
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.0    0.0005         3      21      67 ..      26      72 ..      16      76 .. 0.86
   2 ?    4.9   0.2    0.0049        30      17      45 ..      71      99 ..      70     141 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0005
     DUF3493 21 flYlafaaSaliGalifllrllaaragaesapeleealenlaiqvga 67
                ++  +f a+++iG++ +  +l + r++ +  p+ + al +++ ++g+
  EEA18731.1 26 VFHRGFEAGGVIGLFYANYKLYKHRQQLKLTPPQQAALGGVGKNAGI 72
                5677899******************9999999999998888777665 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.0049
     DUF3493 17 glRlflYlafaaSaliGalifllrllaar 45
                g+R ++Y  +a + liGa  +++ l a  
  EEA18731.1 71 GIRNIFYPTMARASLIGAGASMVLLTARM 99
                68***************988777665554 PP

>> Lipase  Lipase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   4.8e-05      0.29     226     273 ..     136     181 ..     126     182 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 4.8e-05
                 EEEEETTTTS-TTSSS-T--S---HHHHHTTTSGGTHHHHHHHHHHHH CS
      Lipase 226 vDffpNGgseqPGckkvvlskivdedGlwevtqfvaCahlRsvkyyid 273
                   +f+ Ggs  P   +v   ++v   Gl +v  fv C+  R +k+y++
  EEA18731.1 136 STIFVAGGSRPPLSLMVR--EMVGRAGLGAVVGFVGCEVVRKYKLYAS 181
                 568999999988766555..6*************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (183 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       313  (0.0174578); expected 358.6 (0.02)
Passed bias filter:                      252  (0.0140554); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.43
# Mc/sec: 1281.57
//
Query:       EEA18732.1  [L=482]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (482 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       857  (0.0477997); expected 358.6 (0.02)
Passed bias filter:                      624  (0.0348039); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.40
# Mc/sec: 3618.91
//
Query:       EEA18733.1  [L=198]
Description: calcium-binding signaling protein Frq1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      6e-25   84.9  10.8    3.6e-08   32.4   0.1    4.8  5  EF-hand_1     EF hand
    8.7e-25   87.0   5.7    1.9e-15   57.1   0.7    3.3  3  EF-hand_7     EF-hand domain pair
    9.5e-24   81.3   4.9      1e-06   28.2   0.1    5.2  5  EF-hand_6     EF-hand domain
    8.7e-17   59.8  11.6      5e-05   22.6   0.1    4.6  5  EF-hand_5     EF hand
    3.3e-13   49.3  10.8    0.00041   20.1   0.2    4.8  5  EF-hand_8     EF-hand domain pair
    4.4e-10   39.4   4.7     0.0025   17.7   0.2    4.0  4  EF-hand_4     Cytoskeletal-regulatory complex EF hand
    0.00015   22.0   0.6      0.011   16.0   0.1    3.1  3  EF-hand_9     EF-hand domain
     0.0087   16.4   1.9        1.1    9.6   0.3    3.2  2  SPARC_Ca_bdg  Secreted protein acidic and rich in cysteine Ca
  ------ inclusion threshold ------
      0.027   14.3   1.5        5.9    6.8   0.1    3.6  4  EF-hand_10    EF hand
       0.11   11.3   0.4        8.9    5.0   0.0    2.1  2  DUF1679       Protein of unknown function (DUF1679)


Domain annotation for each model (and alignments):
>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       2.8     5e+03      18      26 ..      31      39 ..      29      41 .. 0.73
   2 !    5.8   0.0    0.0063        11      14      27 ..      48      61 ..      48      63 .. 0.87
   3 !   28.4   0.1   3.7e-10   6.7e-07       4      27 ..      75      98 ..      72     100 .. 0.90
   4 !   32.4   0.1     2e-11   3.6e-08       2      27 ..     109     134 ..     108     136 .. 0.92
   5 !   21.9   0.9   4.4e-08     8e-05       2      25 ..     157     180 ..     156     183 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 2.8
                EHHHHHHHH CS
   EF-hand_1 18 dfeEfkell 26
                d++E++++ 
  EEA18733.1 31 DKKELQQWY 39
                778888876 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0063
                SSEEEHHHHHHHHH CS
   EF-hand_1 14 dGkIdfeEfkellk 27
                +G++++eEf+++ +
  EEA18733.1 48 SGHLNKEEFQKIYR 61
                7*********9976 PP

  == domain 3  score: 28.4 bits;  conditional E-value: 3.7e-10
                HHHHHHTTTSSSEEEHHHHHHHHH CS
   EF-hand_1  4 eiFrefDkDgdGkIdfeEfkellk 27
                 +Fr+fD D++G+Idf+Ef+ +l+
  EEA18733.1 75 YVFRVFDSDNSGTIDFKEFICALS 98
                68*****************99885 PP

  == domain 4  score: 32.4 bits;  conditional E-value: 2e-11
                 HHHHHHHHTTTSSSEEEHHHHHHHHH CS
   EF-hand_1   2 lkeiFrefDkDgdGkIdfeEfkellk 27 
                 l+++F+++D DgdGkI+++E++++++
  EEA18733.1 109 LDWAFQLYDIDGDGKISYDEMLAIVE 134
                 89********************9986 PP

  == domain 5  score: 21.9 bits;  conditional E-value: 4.4e-08
                 HHHHHHHHTTTSSSEEEHHHHHHH CS
   EF-hand_1   2 lkeiFrefDkDgdGkIdfeEfkel 25 
                 +k+iF ++DkD +G +d eEfke 
  EEA18733.1 157 VKKIFGMMDKDENGSLDMEEFKEG 180
                 79********************97 PP

>> EF-hand_7  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.3   0.1    0.0002      0.37      20      71 .]      17      61 ..       2      61 .. 0.81
   2 !   29.0   0.1   5.9e-10   1.1e-06      16      69 ..      48      96 ..      45      98 .. 0.87
   3 !   57.1   0.7     1e-18   1.9e-15       2      68 ..     107     179 ..     106     182 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.0002
   EF-hand_7 20 dkeellrllrkifqgagegsklsdeelellfkefDtdk.dGvisfdEFlklyr 71
                ++++l +l++        + +++++el+++ k f +d+ +G ++ +EF+k+yr
  EEA18733.1 17 SPQQLDELVK--------ATHFDKKELQQWYKGFLKDCpSGHLNKEEFQKIYR 61
                4455554444........45677899********999988***********97 PP

  == domain 2  score: 29.0 bits;  conditional E-value: 5.9e-10
   EF-hand_7 16 dgyldkeellrllrkifqgagegsklsdeelellfkefDtdkdGvisfdEFlkl 69
                +g+l+kee+++++r++f     g++ s+    ++f+ fD+d++G+i+f EF  +
  EEA18733.1 48 SGHLNKEEFQKIYRQFF---PFGDP-SP-FANYVFRVFDSDNSGTIDFKEFICA 96
                69*************98...55555.43.677*******************976 PP

  == domain 3  score: 57.1 bits;  conditional E-value: 1e-18
   EF-hand_7   2 eklkeaFkelDtdgdgyldkeellrllrkifqgagegsklsdee......lellfkefDtdkdGvisfdEFlk 68 
                 +kl +aF+++D dgdg+++++e+l ++++i+ + g ++kl+++e      ++++f ++D+d +G+++++EF++
  EEA18733.1 107 DKLDWAFQLYDIDGDGKISYDEMLAIVEAIYKMVGSMVKLPEDEdtpekrVKKIFGMMDKDENGSLDMEEFKE 179
                 799*******************999******9997777777766666667*********************87 PP

>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0      0.39     7e+02      18      27 ..      31      40 ..      29      44 .. 0.87
   2 !    8.1   0.0    0.0016       2.8      13      28 ..      47      62 ..      42      68 .. 0.88
   3 !   28.2   0.1   5.6e-10     1e-06       3      27 ..      74      98 ..      72     105 .. 0.92
   4 !   21.4   0.0   8.4e-08   0.00015       5      26 ..     112     133 ..     112     141 .. 0.91
   5 !   20.4   0.1   1.8e-07   0.00032       2      24 ..     157     179 ..     156     183 .. 0.92

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.39
   EF-hand_6 18 daeElrkalr 27
                d++El+++++
  EEA18733.1 31 DKKELQQWYK 40
                899****997 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0016
   EF-hand_6 13 gdGkidaeElrkalrk 28
                 +G++++eE++k++r+
  EEA18733.1 47 PSGHLNKEEFQKIYRQ 62
                58************96 PP

  == domain 3  score: 28.2 bits;  conditional E-value: 5.6e-10
   EF-hand_6  3 reaFklfDkdgdGkidaeElrkalr 27
                +++F+ fD d++G+id++E++ al+
  EEA18733.1 74 NYVFRVFDSDNSGTIDFKEFICALS 98
                79*********************98 PP

  == domain 4  score: 21.4 bits;  conditional E-value: 8.4e-08
   EF-hand_6   5 aFklfDkdgdGkidaeElrkal 26 
                 aF+l+D dgdGki+++E+ ++ 
  EEA18733.1 112 AFQLYDIDGDGKISYDEMLAIV 133
                 7*****************9986 PP

  == domain 5  score: 20.4 bits;  conditional E-value: 1.8e-07
   EF-hand_6   2 lreaFklfDkdgdGkidaeElrk 24 
                 ++++F ++Dkd +G++d+eE++ 
  EEA18733.1 157 VKKIFGMMDKDENGSLDMEEFKE 179
                 689******************85 PP

>> EF-hand_5  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       3.6   6.4e+03      17      23 ..      31      37 ..      31      37 .. 0.82
   2 !    5.2   0.0     0.009        16      13      24 ..      48      59 ..      48      60 .. 0.89
   3 !   19.0   0.2   3.8e-07   0.00068       4      21 ..      76      93 ..      73      94 .. 0.95
   4 !   22.6   0.1   2.8e-08     5e-05       4      23 ..     112     131 ..     109     133 .. 0.87
   5 !   17.8   0.5   9.1e-07    0.0016       2      23 ..     158     179 ..     157     181 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 3.6
                -HHHHHH CS
   EF-hand_5 17 skeELkt 23
                +k EL++
  EEA18733.1 31 DKKELQQ 37
                7899986 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.009
                SSCE-HHHHHHH CS
   EF-hand_5 13 DGkIskeELktl 24
                +G+++keE++++
  EEA18733.1 48 SGHLNKEEFQKI 59
                69*******985 PP

  == domain 3  score: 19.0 bits;  conditional E-value: 3.8e-07
                HHHHH-SS-SSCE-HHHH CS
   EF-hand_5  4 tFqaiDlNgDGkIskeEL 21
                +F+ +D +++G+I++ E+
  EEA18733.1 76 VFRVFDSDNSGTIDFKEF 93
                6****************9 PP

  == domain 4  score: 22.6 bits;  conditional E-value: 2.8e-08
                 HHHHH-SS-SSCE-HHHHHH CS
   EF-hand_5   4 tFqaiDlNgDGkIskeELkt 23 
                 +Fq  D +gDGkIs +E  +
  EEA18733.1 112 AFQLYDIDGDGKISYDEMLA 131
                 6****************866 PP

  == domain 5  score: 17.8 bits;  conditional E-value: 9.1e-07
                 HHHHHHH-SS-SSCE-HHHHHH CS
   EF-hand_5   2 kdtFqaiDlNgDGkIskeELkt 23 
                 k+ F ++D++  G +++eE+k+
  EEA18733.1 158 KKIFGMMDKDENGSLDMEEFKE 179
                 678*****************96 PP

>> EF-hand_8  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.0      0.12   2.2e+02      22      34 ..      15      27 ..       3      35 .. 0.73
   2 ?    0.7   0.0      0.26   4.7e+02       3      14 ..      49      60 ..      47      67 .. 0.62
   3 !   20.1   0.2   2.3e-07   0.00041      31      49 ..      76      94 ..      72      99 .. 0.91
   4 !   18.6   0.2   6.8e-07    0.0012      25      50 ..     106     131 ..     103     135 .. 0.89
   5 !   10.9   0.9   0.00017      0.31       8      50 ..     134     179 ..     133     183 .. 0.84

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.12
   EF-hand_8 22 glseeevdilfre 34
                +ls++++d+l+++
  EEA18733.1 15 KLSPQQLDELVKA 27
                6*********997 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.26
   EF-hand_8  3 gkItreelrril 14
                g + +ee+++i+
  EEA18733.1 49 GHLNKEEFQKIY 60
                444456666655 PP

  == domain 3  score: 20.1 bits;  conditional E-value: 2.3e-07
   EF-hand_8 31 lfrefDtdgdGkisfeEFc 49
                +fr fD d++G+i+f+EF+
  EEA18733.1 76 VFRVFDSDNSGTIDFKEFI 94
                7*****************7 PP

  == domain 4  score: 18.6 bits;  conditional E-value: 6.8e-07
   EF-hand_8  25 eeevdilfrefDtdgdGkisfeEFcv 50 
                 e+++d+ f + D+dgdGkis++E ++
  EEA18733.1 106 EDKLDWAFQLYDIDGDGKISYDEMLA 131
                 6899*******************776 PP

  == domain 5  score: 10.9 bits;  conditional E-value: 0.00017
   EF-hand_8   8 eelrril.rilglkk..glseeevdilfrefDtdgdGkisfeEFcv 50 
                 e  ++++ ++++l++  ++ e+ v  +f  +D d++G ++ eEF +
  EEA18733.1 134 EAIYKMVgSMVKLPEdeDTPEKRVKKIFGMMDKDENGSLDMEEFKE 179
                 566778888888888988888889999*****************87 PP

>> EF-hand_4  Cytoskeletal-regulatory complex EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.0     0.066   1.2e+02      20      70 ..      10      61 ..       3      66 .. 0.68
   2 !    8.6   0.1   0.00099       1.8      48      71 ..      76      99 ..      70     102 .. 0.86
   3 !   17.7   0.2   1.4e-06    0.0025      41      82 ..     105     145 ..      97     151 .. 0.85
   4 !   10.2   0.1   0.00031      0.56      41      65 ..     153     177 ..     148     182 .. 0.90

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.066
   EF-hand_4 20 kpednkltgdkvapvlknskleedklekiwd..ladidedgkldfeefciamr 70
                  +++kl+ +++  ++k +++++++l++ ++  l d    g+l+ eef  + r
  EEA18733.1 10 LCRQSKLSPQQLDELVKATHFDKKELQQWYKgfLKDCP-SGHLNKEEFQKIYR 61
                45677888888888888888888888886643355554.47777777766555 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.00099
   EF-hand_4 48 iwdladidedgkldfeefciamrl 71
                ++ + d d+ g++df+ef+ a+ +
  EEA18733.1 76 VFRVFDSDNSGTIDFKEFICALSV 99
                7788899***********998865 PP

  == domain 3  score: 17.7 bits;  conditional E-value: 1.4e-06
   EF-hand_4  41 eedklekiwdladidedgkldfeefciamrlifdlvngeikd 82 
                  edkl+  ++l did dgk+ ++e+  ++  i+ +v     +
  EEA18733.1 105 MEDKLDWAFQLYDIDGDGKISYDEMLAIVEAIYKMVGSM-VK 145
                 4799*******************************9654.34 PP

  == domain 4  score: 10.2 bits;  conditional E-value: 0.00031
   EF-hand_4  41 eedklekiwdladidedgkldfeef 65 
                 +e++++ki+ + d de+g+ld+eef
  EEA18733.1 153 PEKRVKKIFGMMDKDENGSLDMEEF 177
                 578899******************9 PP

>> EF-hand_9  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0      0.32   5.7e+02      36      64 ..      34      62 ..      16      64 .. 0.74
   2 !   16.0   0.1   6.1e-06     0.011       2      63 ..      75     134 ..      74     137 .. 0.89
   3 ?    5.5   0.1     0.012        21       3      59 ..     112     178 ..     110     181 .. 0.64

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.32
   EF-hand_9 36 eLeelakelDPdgedasvdldtflrvmre 64
                eL++++k +  d   + ++++ f+++ r+
  EEA18733.1 34 ELQQWYKGFLKDCPSGHLNKEEFQKIYRQ 62
                78888887755555556999999998876 PP

  == domain 2  score: 16.0 bits;  conditional E-value: 6.1e-06
   EF-hand_9   2 tvFevcDtqktGrVpvsrlidyLravtaqdpeeseLeelakelDPdgedasvdldtflrvmr 63 
                  vF+v+D +  G++  ++ i  L  +  +   e +L+   +++D dg  +++  d  l+++ 
  EEA18733.1  75 YVFRVFDSDNSGTIDFKEFICALSVTS-RGKMEDKLDWAFQLYDIDGD-GKISYDEMLAIVE 134
                 68*********************7655.599***************99.9999999888875 PP

  == domain 3  score: 5.5 bits;  conditional E-value: 0.012
   EF-hand_9   3 vFevcDtqktGrVpvsrlidyLravtaq...........dpeeseLeelakelDPdgedasvdldtfl 59 
                  F+++D++  G++   +++++ +a  +            d++e ++ +   ++D d++ +s+d++ f+
  EEA18733.1 112 AFQLYDIDGDGKISYDEMLAIVEAIYKMvgsmvklpedeDTPEKRVKKIFGMMDKDEN-GSLDMEEFK 178
                 6999999999999999888887764332222244334445555577777777776655.677777665 PP

>> SPARC_Ca_bdg  Secreted protein acidic and rich in cysteine Ca binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.1     0.083   1.5e+02      67     111 ..      47      94 ..      11      96 .. 0.64
   2 !    9.6   0.3    0.0006       1.1      51      86 ..     104     139 ..      97     180 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.083
  SPARC_Ca_bdg  67 sdkvlsksELaplraplvkleh...CikpflescDadkdkkislkEwc 111
                     ++l+k+E ++++ ++ ++       +  ++  D+d+ ++i+ kE++
    EEA18733.1  47 PSGHLNKEEFQKIYRQFFPFGDpspFANYVFRVFDSDNSGTIDFKEFI 94 
                   566777888888877777765411134566788888888888888885 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.0006
  SPARC_Ca_bdg  51 eckepvawkFsklDtnsdkvlsksELaplraplvkl 86 
                   ++++++ w F+  D + d+ +s  E+ ++ + + k+
    EEA18733.1 104 KMEDKLDWAFQLYDIDGDGKISYDEMLAIVEAIYKM 139
                   578999*******************99998888776 PP

>> EF-hand_10  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0      0.18   3.3e+02      35      49 ..      48      62 ..      43      63 .. 0.88
   2 ?    2.6   0.0     0.068   1.2e+02      22      43 ..      72      93 ..      70      95 .. 0.90
   3 ?   -3.0   0.0       3.9     7e+03       1       7 [.     123     129 ..     123     135 .. 0.80
   4 ?    6.8   0.1    0.0033       5.9      24      45 ..     158     179 ..     153     183 .. 0.90

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.18
  EF-hand_10 35 sgrLegeEieeFykl 49
                sg L+ eE+++ y++
  EEA18733.1 48 SGHLNKEEFQKIYRQ 62
                899*******99985 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.068
  EF-hand_10 22 YAekLFkkcDkSksgrLegeEi 43
                +A+ +F+  D  +sg+++ +E+
  EEA18733.1 72 FANYVFRVFDSDNSGTIDFKEF 93
                68999************99886 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 3.9
  EF-hand_10   1 kmsfkEv 7  
                 k+s++E+
  EEA18733.1 123 KISYDEM 129
                 7899998 PP

  == domain 4  score: 6.8 bits;  conditional E-value: 0.0033
  EF-hand_10  24 ekLFkkcDkSksgrLegeEiee 45 
                 +k+F   Dk ++g+L+ eE++e
  EEA18733.1 158 KKIFGMMDKDENGSLDMEEFKE 179
                 589999*************987 PP

>> DUF1679  Protein of unknown function (DUF1679)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.1    0.0064        11     329     366 ..      33      67 ..      26      84 .. 0.89
   2 ?    5.0   0.0     0.005       8.9     168     199 ..     123     154 ..     113     194 .. 0.76

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.0064
     DUF1679 329 elLeqyyetflkaledngeepytleqLkdsYklyfplm 366
                 + L+q+y+ flk +    +   + e+ ++ Y+ +fp +
  EEA18733.1  33 KELQQWYKGFLKDC---PSGHLNKEEFQKIYRQFFPFG 67 
                 569***********...3557899************76 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.005
     DUF1679 168 nikadelipvlkaiAtlqalslslseeekksa 199
                 +i+ de++++++ai ++    ++l+e+e +  
  EEA18733.1 123 KISYDEMLAIVEAIYKMVGSMVKLPEDEDTPE 154
                 6899*********************9997654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (198 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       730  (0.0407162); expected 358.6 (0.02)
Passed bias filter:                      632  (0.0352502); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 1404.63
//
Query:       EEA18734.1  [L=239]
Description: nucleoside-diphosphate-sugar epimerase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.3e-08   33.0   0.0    5.8e-08   32.8   0.0    1.2  1  NAD_binding_10  NAD(P)H-binding
    2.1e-07   30.3   0.0    1.3e-06   27.7   0.0    1.9  1  3Beta_HSD       3-beta hydroxysteroid dehydrogenase/isomerase
    1.3e-05   24.8   0.0    2.5e-05   23.8   0.0    1.5  1  Epimerase       NAD dependent epimerase/dehydratase family
    0.00058   19.1   0.0      0.021   14.0   0.0    2.4  3  NAD_binding_4   Male sterility protein
    0.00095   19.3   0.0     0.0016   18.6   0.0    1.5  1  DapB_N          Dihydrodipicolinate reductase, N-terminus
     0.0044   17.4   0.0     0.0073   16.7   0.0    1.5  1  Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domai
  ------ inclusion threshold ------
      0.086   11.9   0.0       0.14   11.3   0.0    1.3  1  RmlD_sub_bind   RmlD substrate binding domain


Domain annotation for each model (and alignments):
>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.8   0.0   2.3e-11   5.8e-08       1     112 [.       7     138 ..       7     217 .. 0.72

  Alignments for each domain:
  == domain 1  score: 32.8 bits;  conditional E-value: 2.3e-11
                     TTTSHHHHHHHHHHHHC-.T-EEEEEETTHHHCHH.HHCTTTCEEEE--TT-.....CCHHHHHHTT-SEEEES---TCCHHHH........... CS
  NAD_binding_10   1 GAtGkvGrllvkellarg.ghevtalvRnpeklae.leaeeglevvegdvtd.....vedlaealkgadaVvsalggggkdeeg........... 77 
                     GAtG vG ++++++l++   ++v+al+R++  +++ ++ +++l+ ++  v +     +++++e l+gada ++ ++ + +++ +           
      EEA18734.1   7 GATGFVGTEVIRQALSHPaVTSVVALARRATPVPAnVSLDANLSKLKCAVCEdfehySDSIKEDLAGADACIWLIAITPSKQSSmpfeqvekicl 101
                     9****************98889*******8888631343456655555443222234699**********9999976666333345566577788 PP

                     ..HHHHHHHH..HHCT--EEEEEEETTTTSGCGCHHHHH CS
  NAD_binding_10  78 ..aknivdaa..keagvkRfvlvsaigvgdevpgefgew 112
                       ++n ++ +  + ++  Rf++ s+++v++++ ++  +w
      EEA18734.1 102 dyTVNGLKTMatRSNNPFRFIYTSGAKVNRDQTKR--PW 138
                     887777776611568899**********9754433..33 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.7   0.0     5e-10   1.3e-06       1     150 [.       4     159 ..       4     209 .. 0.80

  Alignments for each domain:
  == domain 1  score: 27.7 bits;  conditional E-value: 5e-10
   3Beta_HSD   1 vvtGgaGFlGralvkeLvrleelkevrvlDlrespelleelskvnvkk...viegDvtd.kdkleealegvdvvihlaslvdvag.kltedeimkvnvk 94 
                 vv G++GF+G +++++ ++   +  v +l  r  p   + +   n  k    ++ D     d+++e l g+d+ i+l +++++++  + ++++ k+ + 
  EEA18734.1   4 VVAGATGFVGTEVIRQALSHPAVTSVVALARRATPVPANVSLDANLSKlkcAVCEDFEHySDSIKEDLAGADACIWLIAITPSKQsSMPFEQVEKICLD 102
                 799**************************9999998888888888776554566677653578******************998868999999999999 PP

   3Beta_HSD  95 GTrnvle..acvkagvrvlvYtSsaevvgpnslgeeilngdEeleyeslhqdaypesK 150
                  T n l+  a ++++  +++YtS a+v  + +++ + + gd    +  + ++++   K
  EEA18734.1 103 YTVNGLKtmATRSNNPFRFIYTSGAKVNRD-QTKRPWIMGDYGVLRSRVENQVLDFAK 159
                 9999997324455566689*******9988.666676668877666666555555544 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.0     1e-08   2.5e-05       2     183 ..       4     186 ..       3     206 .. 0.76

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 1e-08
                 EEETTTSHHHHHHHHHHHHCT.SE.EEEEES-STTTTCHHCHHC...EEEE--TT-HHHHHHHHHHH..T-SEEEE--S---HHHHHHSHHHHHHHHTH CS
   Epimerase   2 lVtGatGfiGsalvkallekg.ye.vigldrlssasntarledl...elveldltdrsalerlfkee..qpdavihlAavggvaassedpadfieknlq 93 
                 +V+GatGf+G+ ++++ l++  ++ v++l+r+ +  + +   d+   +l  +   d +   + +ke   ++da i l a+   ++ss   +++ ++ l 
  EEA18734.1   4 VVAGATGFVGTEVIRQALSHPaVTsVVALARRATPVPANVSLDAnlsKLKCAVCEDFEHYSDSIKEDlaGADACIWLIAITPSKQSSMPFEQVEKICLD 102
                 79*******************9666*******99999988888856422222233444555555555569*******997777777777788888999* PP

                 HHHHHHHHHHHH..TCTEEEEEEEGGGGTSCSSSSBSTCSTTS----SSHHHHHHHHHHHHHHHHHHHHT...-EEEEEEESEEESTTS-TTSTT CS
   Epimerase  94 gtlnlleaarka..gvkrllflsSsevYGkdaeqpkeettltgplkpnspYaaaKlageklveayaaqyg...lnaiilrlfnlyGprngegevs 183
                 +t+n l+ + ++  ++ r+++ s + v  ++++          p      Y++    +e++v ++a+q +   ++++i+r+  +y p+ ++++ +
  EEA18734.1 103 YTVNGLKTMATRsnNPFRFIYTSGAKVNRDQTKR---------P-WIMGDYGVLRSRVENQVLDFAKQPDgknVQVCITRPGLIYAPG-HMSTLT 186
                 ****9998876545888*****997665554443.........2.35899***************99984466999*********999.333333 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.0   0.0   8.2e-06     0.021       2      46 ..       6      50 ..       5      67 .. 0.83
   2 ?   -3.1   0.0       1.4   3.5e+03     122     143 ..     112     133 ..      95     138 .. 0.57
   3 ?    2.6   0.0     0.025        65     194     218 ..     164     185 ..     152     216 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 8.2e-06
                   E-TTSHHHHHHHHHHHHHS-.T.EEEEEE-SSSHHHHHHHHHHHT- CS
  NAD_binding_4  2 TGaTGFLGkvLlekLLrttpev.kiyllvRaksgesaeeRleeele 46
                    GaTGF+G+ ++++ L+  + v  +++l+R  +   a+  l+++l 
     EEA18734.1  6 AGATGFVGTEVIRQALSHPA-VtSVVALARRATPVPANVSLDANLS 50
                   7***************8876.66*******9888777777766665 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 1.4
                    HTSSS--.-EEEEEEGGGTTS- CS
  NAD_binding_4 122 akklkklkvllhvSTayvnger 143
                    a++ ++   +++ S a vn+++
     EEA18734.1 112 ATRSNNPFRFIYTSGAKVNRDQ 133
                    3333333334444445555554 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.025
                    H---EEEEEE-EEE--SSST---TT CS
  NAD_binding_4 194 sglpvvivRpsiitgesktGwings 218
                    ++++v+i Rp+ i++   +G + + 
     EEA18734.1 164 KNVQVCITRPGLIYA---PGHMSTL 185
                    5899*********98...3333333 PP

>> DapB_N  Dihydrodipicolinate reductase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0   6.2e-07    0.0016       1      67 [.       1      66 [.       1     107 [. 0.88

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 6.2e-07
                EEEEEETTTSHHHHHHHHHHHHSTTEEEEEEEETTCSTTTTTBHHHHSSSS--S-BEBSSHHHHHHH CS
      DapB_N  1 ikvavvGasGrmGkevvkaveeaedlelvaavdrkeselegkdagellglgklgvavtddleevlek 67
                +k++v+Ga+G +G+ev++ + +++ ++ v a+ r+  + +  +++  ++l+kl++av +d+e+  ++
  EEA18734.1  1 MKLVVAGATGFVGTEVIRQALSHPAVTSVVALARRA-TPVPANVSLDANLSKLKCAVCEDFEHYSDS 66
                89********************************98.666678888899999999999998877665 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   2.8e-06    0.0073       3      35 ..       4      36 ..       2      96 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 2.8e-06
                    EEETTTSHHHHHHHHHHHCTSSEEEEEEEESTT CS
  Semialdhyde_dh  3 aivGatGyvGqellrlLeehpevelvvllsssr 35
                     + GatG vG+e++r   +hp v+ vv+l+++ 
      EEA18734.1  4 VVAGATGFVGTEVIRQALSHPAVTSVVALARRA 36
                    689************************999987 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   5.4e-05      0.14       1      53 [.       1      55 [.       1      66 [. 0.80

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 5.4e-05
                   EEEEEESTTSHHHHHHHHHCTT..TSEEEEEE-TTT--TTSHHHHHHHHHHH--S CS
  RmlD_sub_bind  1 mkilvtGanGqlGseLakqlae..eglevlaltreeldltdaeavaellkeakpd 53
                   mk++v Ga+G +G+e+++q+ +  + ++v+al r+++ +  + ++++ l++ k++
     EEA18734.1  1 MKLVVAGATGFVGTEVIRQALShpAVTSVVALARRATPVPANVSLDANLSKLKCA 55
                   89**************999876335568999999988888777777777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (239 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       419  (0.02337); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 1629.62
//
Query:       EEA18735.1  [L=646]
Description: endosomal integral membrane protein (P24a), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.2e-200  666.7   5.2   3.1e-200  666.3   5.2    1.2  1  EMP70     Endomembrane protein 70


Domain annotation for each model (and alignments):
>> EMP70  Endomembrane protein 70
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  666.3   5.2  1.7e-204  3.1e-200       1     518 [.      62     602 ..      62     603 .. 0.95

  Alignments for each domain:
  == domain 1  score: 666.3 bits;  conditional E-value: 1.7e-204
       EMP70   1 pydYyd.llpfCkpeeekkkesesLgevLrGdrienspyelkfgkdeeckvlCt.kkltkeelkklkelIkngYvvnwlvDnLPva.........tsfv 88 
                 +ydYy+ +++fC+p++   + +esLg++++Gdri++sp+el++ k+e+ck++C   ++  +++++ +++I +gY +nwlvD+LP+a          +f+
  EEA18735.1  62 SYDYYNpIFHFCQPKDGPVDVRESLGSIIFGDRIRTSPFELHMAKNETCKAVCGeVEFGPRDARFTNNRIAQGYNINWLVDGLPAAmlnldpftgAEFY 160
                 59****9*******865667778******************************66*******************************9999998888888 PP

       EMP70  89 saaGfplGfvdkeeekekyylnnhldfviryhkakeee..kkrivgfevepksvkde.e..e..eeCpkeae.leleeekkeeeteipftYsVkwrese 179
                 + +Gf +G+vd+   +++ +lnnh+ + i+yhk+   +  k+r+vg+ v+p+s  d+    +   +C +  + + l+e   e  t++ +tYsV+wres+
  EEA18735.1 161 N-PGFLMGYVDE---DGQSVLNNHFIIFIDYHKVGLATqdKYRVVGVLVQPESRGDSfVsgNnqVDCGEGGNaMILSE---EIPTKVVWTYSVYWRESN 252
                 8.7********7...799***************976656799*************98744524566887775377777...689**************8 PP

       EMP70 180 dvewasRwdlylesvedskihwfsiinslvivlllslivavillrtlrkdiarynee............eeee.aqeesgWKlvhgdVfrpPknsllLs 265
                  + wa+Rwd+yl +v d+kihwfs+ins+v+v++l+++v++il+r+lrkdiaryn+               e+ +qe+sgWKlvhgdVfr Pk +llLs
  EEA18735.1 253 -TAWATRWDKYL-HVFDPKIHWFSLINSSVFVVFLVGMVSMILIRALRKDIARYNRLdqinlddlngtsVVEDgIQEDSGWKLVHGDVFRCPKSPLLLS 349
                 .***********.899****************************************99999988887763335699*********************** PP

       EMP70 266 vlvGsGvqlllmalvtlllallgflspsnrgslltvalllyvllgliaGYvsarlyktfggekwkkntlltalllpgllflvffllnlilwakessgal 364
                 vl+G+G+ql++m+ vt+++al+g+lsp+nrg l t++++ly+l+g+i+GYvs+r yk+fgge wk+n+++t+ll+p ++f+ ffllnl++wak+ssga+
  EEA18735.1 350 VLLGNGAQLFVMTGVTVAFALFGLLSPANRGFLGTTVVILYTLFGFIGGYVSSRAYKSFGGEAWKRNIVMTPLLIPSIVFSWFFLLNLFVWAKGSSGAV 448
                 *************************************************************************************************** PP

       EMP70 365 pfgtlvlllllwflisvPlvliGsllgfkkkaiehpvrtnqiprqipkqpwylkpllsvllgGilpFgaifielyfilsslwlekiYylfgfLflvfll 463
                 pf+t+++++++wf+isvPl+++Gs++gfk++a+e p++tnqiprqip+    l+p++s+ll+GilpFgaif+elyfi++slw +kiYy+fgfLfl++ l
  EEA18735.1 449 PFTTMIAVVAIWFVISVPLSFAGSWIGFKSQAFEAPTKTNQIPRQIPPAVGTLRPIPSLLLTGILPFGAIFVELYFIMNSLWTSKIYYMFGFLFLCYGL 547
                 *****************************9899***************9************************************************** PP

       EMP70 464 liittaevtilltYfqLcaedyrWwWrSflvggssalYvflysiyYyftklkisg 518
                 ++itta +till+Yf+LcaedyrW Wr+f  +g++++Yvf+ ++++++t++++ g
  EEA18735.1 548 MVITTAATTILLVYFMLCAEDYRWSWRAFNGAGMTGFYVFVNALIFWATRVSFGG 602
                 **************************************************99866 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (646 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       834  (0.0465168); expected 358.6 (0.02)
Passed bias filter:                      314  (0.0175135); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.34s 00:00:00.97 Elapsed: 00:00:00.49
# Mc/sec: 3969.44
//
Query:       EEA18736.1  [L=174]
Description: hypothetical protein PMAA_010190 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
  ------ inclusion threshold ------
       0.11   12.9   0.0       0.19   12.2   0.0    1.3  1  HSP9_HSP12  Heat shock protein 9/12


Domain annotation for each model (and alignments):
>> HSP9_HSP12  Heat shock protein 9/12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0     1e-05      0.19       2      29 ..     109     136 ..     108     144 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 1e-05
                 --S-SSCHHHHHHHHCS--SSHCHHHHH CS
  HSP9_HSP12   2 SDagRkdftdkakeevtPDsqKStleka 29 
                 S +gR  + dk  +++ PDs KS   + 
  EEA18736.1 109 SSSGRDRLFDKNANTLSPDSAKSICSQG 136
                 778999*****************98776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (174 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       552  (0.0307881); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.25s 00:00:00.67 Elapsed: 00:00:00.42
# Mc/sec: 1237.96
//
Query:       EEA18737.1  [L=398]
Description: U3 small nucleolar ribonucleoprotein protein Lcp5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.6e-18   67.1   0.2    1.6e-18   67.1   0.2    1.9  2  Sas10_Utp3      Sas10/Utp3/C1D family
  ------ inclusion threshold ------
       0.68    8.2   3.0       0.89    7.8   3.0    1.1  1  GCP5-Mod21      gamma-Tubulin ring complex non-core subunit m
        1.1    9.9   9.1        8.3    7.0   9.2    2.4  1  Striatin        Striatin family
        3.7    8.0  11.0          8    6.9  11.0    1.5  1  CENP-B_dimeris  Centromere protein B dimerisation domain
        5.1    6.3  11.7        9.6    5.4  11.7    1.4  1  NOA36           NOA36 protein


Domain annotation for each model (and alignments):
>> Sas10_Utp3  Sas10/Utp3/C1D family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.1   0.2   4.6e-22   1.6e-18       1      87 []      28     119 ..      28     119 .. 0.83
   2 ?   -2.2   0.3       1.9   6.9e+03      21      21 ..     155     155 ..     128     186 .. 0.49

  Alignments for each domain:
  == domain 1  score: 67.1 bits;  conditional E-value: 4.6e-22
  Sas10_Utp3   1 leslsksldelqeslepllskakaeekkslsd.eklsegisllslKnelllaYllnlllylllklsg.........velkdhpvvkeLvrlRvyleK 87 
                 le+l+++l+++++sl++ ++++++ +  s     ++s+gisll++K elll+Yl+nl++++l++l+g         v  +  +vv +L++lRvyle+
  EEA18737.1  28 LETLTECLNSASTSLPSSTESEDKTT--SP-TiLPPSDGISLLDTKAELLLSYLQNLVFLVLFQLRGrgksegqgdV--SLEDVVRKLTELRVYLER 119
                 89***************877433222..33.259*********************************8777666443..3345*************7 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.9
  Sas10_Utp3  21 k 21 
                 k
  EEA18737.1 155 K 155
                 1 PP

>> GCP5-Mod21  gamma-Tubulin ring complex non-core subunit mod21
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   3.0   0.00025      0.89     104     152 ..     162     208 ..     122     223 .. 0.77

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.00025
  GCP5-Mod21 104 sssdddesvtkseEeeevtdeneeinepsnfPhipvieksenfekqdli 152
                 ++sd+ e v  ++E+ee+  +neei+e ++ P++     s+++ k d+ 
  EEA18737.1 162 DDSDNSEDVSDDDEDEEEDSDNEEIDEMAYRPNVTA--FSKDVPKADRD 208
                 56788899************************9987..66666666665 PP

>> Striatin  Striatin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   9.2    0.0023       8.3      36     118 ..     102     206 ..     101     368 .. 0.74

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0023
    Striatin  36 kLegerrgaenlkkdlvrrikmLEyalkqerakylkl......kegtsaakenkkkekeeeeaeeeekseees.kskekksakeslkks.......... 117
                 +Le   r+  +l+  l r +k LE  lk +  k++k              ++++ k+ ++ +++  ++s++++  s++++  +e+ +++          
  EEA18737.1 102 SLEDVVRKLTELRVYLERGVKPLEGRLKYQIDKVVKAaedaerA------SKSAPKAGKKIKNKGGDDSDNSEdVSDDDEDEEEDSDNEeidemayrpn 194
                 57888999999********************9988875544331......2222222222222222221111101111111111111112333455555 PP

    Striatin 118 ...........e 118
                            +
  EEA18737.1 195 vtafskdvpkaD 206
                 665555444430 PP

>> CENP-B_dimeris  Centromere protein B dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9  11.0    0.0022         8       8      45 ..     160     197 ..     154     214 .. 0.66

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0022
  CENP-B_dimeris   8 agedsesesdeeeeeeeedeededeeddedddevpvps 45 
                     +g+ds+   d  +++e+e+e+ ++ee de      v +
      EEA18737.1 160 GGDDSDNSEDVSDDDEDEEEDSDNEEIDEMAYRPNVTA 197
                     67777766666666666555555556666555545555 PP

>> NOA36  NOA36 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4  11.7    0.0027       9.6     247     299 ..     142     185 ..     125     194 .. 0.37

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.0027
       NOA36 247 ddddeedsdydaylkalasgddeddegdedddddddeedddeeeddedeeeee 299
                 ++  ++++          +g++ +++g +d d+ +d  +dd+e+++ed+++ee
  EEA18737.1 142 AERASKSA--------PKAGKKIKNKGGDDSDNSED-VSDDDEDEEEDSDNEE 185
                 22222222........22223333443333333332.2222222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (398 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1147  (0.0639746); expected 358.6 (0.02)
Passed bias filter:                      569  (0.0317363); expected 358.6 (0.02)
Passed Vit filter:                        69  (0.00384851); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.60u 0.32s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 2638.66
//
Query:       EEA18738.1  [L=144]
Description: heat-stable 19 kDa antigen precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.7e-36  124.3   1.4    3.2e-36  124.0   1.4    1.1  1  Cerato-platanin  Cerato-platanin


Domain annotation for each model (and alignments):
>> Cerato-platanin  Cerato-platanin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  124.0   1.4   1.8e-40   3.2e-36       4     118 ..      30     143 ..      27     144 .] 0.97

  Alignments for each domain:
  == domain 1  score: 124.0 bits;  conditional E-value: 1.8e-40
  Cerato-platanin   4 sydtgyddanrsltvvscsdGsnGlitkywptqgavknfpriGGlsaiagwnsancGtcykityngktiyvlaidaagaGfniakkamdeltng 97 
                      +yd+ ydda  sl++v+cs+G+nGl+tk ++  g ++  p++ G  +i gwn ancG+cy+++y+++t+yv+aid a + fn a++ +d+lt+g
       EEA18738.1  30 TYDAAYDDATLSLSTVTCSNGENGLVTKGYNSIGDLPT-PYVAGSLTIKGWNDANCGACYSLSYKNETVYVVAIDVAIGKFNAAQRVLDKLTQG 122
                      7***************************9999999996.9****************************************************** PP

  Cerato-platanin  98 qaaelGrvdaeveevalsdcg 118
                      +a+e+G v  ++eev+ s+cg
       EEA18738.1 123 HAEEFGSVLVDYEEVDGSKCG 143
                      ********************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (144 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       546  (0.0304535); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.30s 00:00:00.74 Elapsed: 00:00:00.46
# Mc/sec: 942.22
//
Query:       EEA18739.1  [L=692]
Description: glutaminase GtaA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.9e-76  256.2   6.0    4.9e-76  255.5   6.0    1.4  1  DUF5127        Domain of unknown function (DUF5127)
    2.8e-74  248.5   0.6    5.5e-74  247.6   0.6    1.5  1  DUF4965        Domain of unknown function (DUF4965)
    3.1e-66  222.9   1.1    3.1e-66  222.9   1.1    2.4  2  DUF1793        Domain of unknown function (DUF1793)
    9.3e-08   31.5   0.2    4.9e-07   29.2   0.0    2.3  2  DUF4964        Domain of unknown function (DUF4964)
     0.0064   16.5   1.5      0.018   15.0   0.9    2.1  2  Phage_T4_gp36  Phage T4 tail fibre


Domain annotation for each model (and alignments):
>> DUF5127  Domain of unknown function (DUF5127)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  255.5   6.0   1.4e-79   4.9e-76       1     227 []     104     335 ..     104     335 .. 0.98

  Alignments for each domain:
  == domain 1  score: 255.5 bits;  conditional E-value: 1.4e-79
     DUF5127   1 tqtiftftaggkveltvtFlSPvlpddldrqSlpfsYltvevkstdgkshsVqvYsdisaewasgdesqevewsttt.gglayhkvgrqnqevlseknd 98 
                 t++i++ t+++k +++vtFlSP++p+d+ rqSl fsY+tvev s+dg++h+V +Y+disaew+sgd+s +++w+++t g+l+yhkv+rq++  +se +d
  EEA18739.1 104 TSSIYVQTVEDKLQIKVTFLSPITPNDFLRQSLIFSYMTVEVVSLDGSEHNVALYTDISAEWVSGDRSVVAQWDYGTnGDLSYHKVYRQTKLAFSEVSD 202
                 89*************************************************************************9657******************** PP

     DUF5127  99 radwGyaylatkakss.ltyqsgedtevrkqFvkngklantkdtnfraisddwpvfalahdlgsvssesksvvfaiGyvrdpaiqylg....qnlrpyW 192
                 ++++G+++++t+ ++s +ty sg ++evr+qF+k g+l+n+ d+n+rai+d+wpvfa a+dlgsv+++s+s++f+iG+++++aiq+ g     +l+++W
  EEA18739.1 203 QTEYGNWWYTTT-SDSgYTYGSGFADEVRGQFIKYGALTNNVDSNYRAIRDRWPVFAHAFDLGSVGTTSTSRLFSIGLTQEEAIQFDGadgvVPLPSFW 300
                 ************.7778************************************************9989*******************999******** PP

     DUF5127 193 rskyssiedalsaflkdyaaalkrsealDkkirad 227
                  +++s+  +a+s+f++dy++a++ s++lD+k+ +d
  EEA18739.1 301 LQYFSDEISAMSFFHNDYETASSLSADLDAKVLSD 335
                 *******************************9876 PP

>> DUF4965  Domain of unknown function (DUF4965)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  247.6   0.6   1.5e-77   5.5e-74       2     174 .]     339     509 ..     338     509 .. 0.98

  Alignments for each domain:
  == domain 1  score: 247.6 bits;  conditional E-value: 1.5e-77
     DUF4965   2 ggekYadllalsvRqafaalelvskdetsevllflKeissngnvntvDviypalPlflylnpellkllLeplleyqesgkypkkfaahDlGtsYPnatg 100
                  +++Ya + +ls+Rqaf+a++lv   ++ + +lflKeiss+gnvntvDvi+pa+P +ly+np+ll+l+++pl+e+qe+g+yp+++++hD+G++YPnat 
  EEA18739.1 339 ISHDYAIIATLSLRQAFGATQLV--GTNRTQYLFLKEISSDGNVNTVDVIFPAHPAYLYTNPALLRLVMAPLFENQEAGQYPNRWSMHDVGSHYPNATA 435
                 689********************..4568899******************************************************************* PP

     DUF4965 101 qndgedeqmpveesGnmlimalayaqasgdasllekyydllkqWadYLvengldpanqlstddfagalanqtnL 174
                 + dg+deqmp+ee+Gnmlim lay+ as+d ++l+++y+ll+qW+++Lv+++l+panq+stddfag+lanqtnL
  EEA18739.1 436 HPDGSDEQMPLEECGNMLIMSLAYYLASKDLDFLKSHYRLLDQWTQFLVDEALYPANQISTDDFAGSLANQTNL 509
                 *************************************************************************8 PP

>> DUF1793  Domain of unknown function (DUF1793)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.3      0.55     2e+03      13      63 ..     149     203 ..     142     269 .. 0.70
   2 !  222.9   1.1   8.6e-70   3.1e-66       1     166 []     515     685 ..     515     685 .. 0.97

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.55
     DUF1793  13 lgeeedakkysaiaeeyikkweelai...dgthlklaYdk.edswsllYnlyaDk 63 
                  g+e++ + y++i++e+++  +++      gt   l+Y+k +   +l+++ ++D+
  EEA18739.1 149 DGSEHNVALYTDISAEWVSGDRSVVAqwdYGTNGDLSYHKvYRQTKLAFSEVSDQ 203
                 5666666778888887777755544435333677777777777777777777776 PP

  == domain 2  score: 222.9 bits;  conditional E-value: 8.6e-70
     DUF1793   1 iGikAmseiaellgeeedakkysaiaeeyikkweelaidg....thlklaYdkedswsllYnlyaDkllglnlvpqsvyemqsafYktvaqkyGlplDs 95 
                 iGikAms ia+++g++++a++ys+ia++yi++w++l+i++    +h +l+Yd++dsw+llYnl+ Dk lglnlvpqsvy+mqs+fY+tv  kyG+plD+
  EEA18739.1 515 IGIKAMSVIASVTGNHTSAANYSSIADDYITQWQTLGINSaanpPHSTLSYDSSDSWGLLYNLFGDKELGLNLVPQSVYDMQSNFYPTVNAKYGVPLDT 613
                 8*************************************4445668****************************************************** PP

     DUF1793  96 rhtytksdWelfaaavaskktreelissvakwvnetktdrpftdlYdtegtgglpg..frarpvvGGhFalLa 166
                 rh+ytk dWe++aa++as++tr+++ s++a w+n+t t++++tdlYdt  t ++pg  f++rpv+GG+Fa L+
  EEA18739.1 614 RHSYTKGDWEAWAASIASETTRDMFYSDLAYWINNTPTNHALTDLYDT-VTDDYPGifFINRPVMGGVFAQLV 685
                 ***********************************************9.799******************985 PP

>> DUF4964  Domain of unknown function (DUF4964)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.2   0.0   1.4e-10   4.9e-07      22      78 ..      24      87 ..       8      94 .. 0.83
   2 ?   -2.1   0.0      0.82   2.9e+03      24      46 ..     401     426 ..     392     446 .. 0.65

  Alignments for each domain:
  == domain 1  score: 29.2 bits;  conditional E-value: 1.4e-10
     DUF4964 22 seLRaPayPLvtidpylsiWsftde.......LndesvkhwtgkdlpllgvlrVDGkvYrfmGk 78
                s  R Pa PL +  pyls+W  + +       L ++  ++w+g+ l   g+++VDG  Y +mG 
  EEA18739.1 24 SPARPPAQPLAVKSPYLSAWQSAGSnggnggyLANQWPTFWSGQILGWAGLIKVDGIAYGWMGV 87
                5569****************654322333444999999*************************5 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.82
     DUF4964  24 LRaPayPLvtid...pylsiWsftde 46 
                 LR+ + PL  ++    y + Ws+ d 
  EEA18739.1 401 LRLVMAPLFENQeagQYPNRWSMHDV 426
                 66666777655422268899999984 PP

>> Phage_T4_gp36  Phage T4 tail fibre
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0         2   7.3e+03       1      23 [.     181     203 ..     181     218 .. 0.83
   2 !   15.0   0.9   5.1e-06     0.018       5      69 ..     499     567 ..     495     570 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 2
  Phage_T4_gp36   1 agdtmagtvkstaklhvseasns 23 
                    +gd+   +v+ ++kl  se s+ 
     EEA18739.1 181 NGDLSYHKVYRQTKLAFSEVSDQ 203
                    58889999999999999998875 PP

  == domain 2  score: 15.0 bits;  conditional E-value: 5.1e-06
  Phage_T4_gp36   5 magtvkstaklhvseasnsqakgglvngngdaatfdka....nvdiksWygigfkssfesrGagvvfdt 69 
                     ag + ++++l ++   +++a+  + + +g++ ++ ++    +  i +W+ +g++s  +    +  +d+
     EEA18739.1 499 FAGSLANQTNLALKGMIGIKAMSVIASVTGNHTSAANYssiaDDYITQWQTLGINSAANPPHSTLSYDS 567
                    68999**************************99987653233778***********9998878888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (692 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       313  (0.0174578); expected 358.6 (0.02)
Passed bias filter:                      243  (0.0135535); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.44
# Mc/sec: 4671.87
//
Query:       EEA18740.1  [L=504]
Description: glutaminase GtaA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-76  257.1   6.0    2.5e-76  256.5   6.0    1.3  1  DUF5127   Domain of unknown function (DUF5127)
    8.4e-71  237.2   0.3    1.5e-70  236.4   0.3    1.4  1  DUF4965   Domain of unknown function (DUF4965)
    6.9e-08   31.9   0.2    3.1e-07   29.8   0.0    2.1  2  DUF4964   Domain of unknown function (DUF4964)


Domain annotation for each model (and alignments):
>> DUF5127  Domain of unknown function (DUF5127)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  256.5   6.0   4.1e-80   2.5e-76       1     227 []     104     335 ..     104     335 .. 0.98

  Alignments for each domain:
  == domain 1  score: 256.5 bits;  conditional E-value: 4.1e-80
     DUF5127   1 tqtiftftaggkveltvtFlSPvlpddldrqSlpfsYltvevkstdgkshsVqvYsdisaewasgdesqevewsttt.gglayhkvgrqnqevlseknd 98 
                 t++i++ t+++k +++vtFlSP++p+d+ rqSl fsY+tvev s+dg++h+V +Y+disaew+sgd+s +++w+++t g+l+yhkv+rq++  +se +d
  EEA18740.1 104 TSSIYVQTVEDKLQIKVTFLSPITPNDFLRQSLIFSYMTVEVVSLDGSEHNVALYTDISAEWVSGDRSVVAQWDYGTnGDLSYHKVYRQTKLAFSEVSD 202
                 89*************************************************************************9657******************** PP

     DUF5127  99 radwGyaylatkakss.ltyqsgedtevrkqFvkngklantkdtnfraisddwpvfalahdlgsvssesksvvfaiGyvrdpaiqylg....qnlrpyW 192
                 ++++G+++++t+ ++s +ty sg ++evr+qF+k g+l+n+ d+n+rai+d+wpvfa a+dlgsv+++s+s++f+iG+++++aiq+ g     +l+++W
  EEA18740.1 203 QTEYGNWWYTTT-SDSgYTYGSGFADEVRGQFIKYGALTNNVDSNYRAIRDRWPVFAHAFDLGSVGTTSTSRLFSIGLTQEEAIQFDGadgvVPLPSFW 300
                 ************.7778************************************************9989*******************999******** PP

     DUF5127 193 rskyssiedalsaflkdyaaalkrsealDkkirad 227
                  +++s+  +a+s+f++dy++a++ s++lD+k+ +d
  EEA18740.1 301 LQYFSDEISAMSFFHNDYETASSLSADLDAKVLSD 335
                 *******************************9876 PP

>> DUF4965  Domain of unknown function (DUF4965)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  236.4   0.3   2.5e-74   1.5e-70       2     169 ..     339     504 .]     338     504 .] 0.98

  Alignments for each domain:
  == domain 1  score: 236.4 bits;  conditional E-value: 2.5e-74
     DUF4965   2 ggekYadllalsvRqafaalelvskdetsevllflKeissngnvntvDviypalPlflylnpellkllLeplleyqesgkypkkfaahDlGtsYPnatg 100
                  +++Ya + +ls+Rqaf+a++lv   ++ + +lflKeiss+gnvntvDvi+pa+P +ly+np+ll+l+++pl+e+qe+g+yp+++++hD+G++YPnat 
  EEA18740.1 339 ISHDYAIIATLSLRQAFGATQLV--GTNRTQYLFLKEISSDGNVNTVDVIFPAHPAYLYTNPALLRLVMAPLFENQEAGQYPNRWSMHDVGSHYPNATA 435
                 689********************..4568899******************************************************************* PP

     DUF4965 101 qndgedeqmpveesGnmlimalayaqasgdasllekyydllkqWadYLvengldpanqlstddfagala 169
                 + dg+deqmp+ee+Gnmlim lay+ as+d ++l+++y+ll+qW+++Lv+++l+panq+stddfag+la
  EEA18740.1 436 HPDGSDEQMPLEECGNMLIMSLAYYLASKDLDFLKSHYRLLDQWTQFLVDEALYPANQISTDDFAGSLA 504
                 ******************************************************************986 PP

>> DUF4964  Domain of unknown function (DUF4964)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.8   0.0   5.2e-11   3.1e-07      22      78 ..      24      87 ..       8      94 .. 0.83
   2 ?   -1.5   0.0      0.32   1.9e+03      24      46 ..     401     426 ..     391     446 .. 0.66

  Alignments for each domain:
  == domain 1  score: 29.8 bits;  conditional E-value: 5.2e-11
     DUF4964 22 seLRaPayPLvtidpylsiWsftde.......LndesvkhwtgkdlpllgvlrVDGkvYrfmGk 78
                s  R Pa PL +  pyls+W  + +       L ++  ++w+g+ l   g+++VDG  Y +mG 
  EEA18740.1 24 SPARPPAQPLAVKSPYLSAWQSAGSnggnggyLANQWPTFWSGQILGWAGLIKVDGIAYGWMGV 87
                5569****************654322333444999999*************************5 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.32
     DUF4964  24 LRaPayPLvtid...pylsiWsftde 46 
                 LR+ + PL  ++    y + Ws+ d 
  EEA18740.1 401 LRLVMAPLFENQeagQYPNRWSMHDV 426
                 66667777665422268899999984 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (504 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       399  (0.0222544); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.48
# Mc/sec: 3155.95
//
Query:       EEA18741.1  [L=651]
Description: alkaline serine protease AorO, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.3e-47  159.2   0.2    2.3e-46  157.6   0.0    1.9  2  Pro-kuma_activ  Pro-kumamolisin, activation domain
    0.00017   21.0   3.0    0.00033   20.0   3.0    1.4  1  Peptidase_S8    Subtilase family


Domain annotation for each model (and alignments):
>> Pro-kuma_activ  Pro-kumamolisin, activation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  157.6   0.0   2.6e-50   2.3e-46       2     139 ..      37     176 ..      36     179 .. 0.98
   2 ?   -2.5   0.0      0.66   5.9e+03     116     135 ..     224     243 ..     221     249 .. 0.72

  Alignments for each domain:
  == domain 1  score: 157.6 bits;  conditional E-value: 2.6e-50
  Pro-kuma_activ   2 gwtkrgraasstllpvrigLkqnnlekledflmdvsdpkspnygkhltaeevaelfapseeaidaVrnwLessgiaasr..hsdtkgwiafsatv 94 
                      w++  r++s+t lpvrigL+q+n + ++d+lmdvs+p+spny+k++t +ev++ fapse+a++aVr wL ++gia +r   s++k+w++f++++
      EEA18741.1  37 SWVEPRRVDSQTALPVRIGLTQSNSDVGHDLLMDVSNPNSPNYRKYMTVHEVNDFFAPSEKAVSAVRTWLANAGIASDRvsLSANKQWLQFDGHA 131
                     69999**************************************************************************999************* PP

  Pro-kuma_activ  95 aqverllktsfeaYshkkgssslarcdeyslPealknyvdyihpt 139
                      +verll+t+++ Y+h++++++++ c+ey++P++l++++dyi+p 
      EEA18741.1 132 DEVERLLGTEYYIYTHEDSGRTHLGCEEYHVPKHLSEHIDYITPG 176
                     ******************************************996 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.66
  Pro-kuma_activ 116 slarcdeyslPealknyvdy 135
                       + cd+ ++P++++   + 
      EEA18741.1 224 AATSCDTTITPDCIRTMYNI 243
                     567899*******9966555 PP

>> Peptidase_S8  Subtilase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   3.0   3.7e-08   0.00033     122     265 ..     393     586 ..     373     600 .. 0.65

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 3.7e-08
                   -SEEEE-EE.SCETTCHHCHHHHHHHHHHHH.CCT-EEEEE--SS-T-HH.....EEE-TTCEECTTTSTTCEEEEEES.................. CS
                   xxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxx.................. RF
  Peptidase_S8 122 vdvinmslg.estslpktgrsiealainravnkkgvlvviSaGNngktgs.....slqagspvgtpstsknvitvgayt.................. 194
                     v+++s+g ++ sl+ ++++ +  +++++   +gv vv+++G +g  g      +  +  +  +p+++  ++tvga+                   
    EEA18741.1 393 TNVVSISYGgDEISLSANYQKRQCDEFKKLG-LQGVSVVVASGDSGVAGAqgcqgKSGSVFNPDFPAGCPYITTVGATYlpkgasasggkevavsrf 488
                   45999***97556666666655444999999.68************7777544322222333334777789999999999*********55555555 PP

                   ....................................TTSSB-TT--B-TT.......-EEEE-S-CCCCCCCCCHHHTTTHH............... CS
                   ....................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............... RF
  Peptidase_S8 195 ....................................tegkiapfSsrGpssdgklkpdivapGgnivstwsrqsnnsaglss............... 240
                                                       t                                            +               
    EEA18741.1 489 asgggfsniyprpayqadavntyltkhtpsyksyntT--------------------------------------------Dnanigangglynaag 541
                   5555555555555555555555544444444444320............................................2444555555555555 PP

                   ....................EEEE-SHHHCHHHHHHHHHHHHHHH CS
                   ....................xxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8 241 ....................yqsmsGTSmAsPnaagaaAlllsal 265
                                         ++ GTS+++P+ a++++ + ++l
    EEA18741.1 542 rgypdvaavgdnvliynagkASLIGGTSASAPVFAAILTRINEEL 586
                   55555555555556655555789***************9998854 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (651 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       393  (0.0219198); expected 358.6 (0.02)
Passed bias filter:                      346  (0.0192983); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.80u 0.35s 00:00:01.14 Elapsed: 00:00:00.60
# Mc/sec: 3290.32
//
Query:       EEA18742.1  [L=239]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    6.1e-09   35.9   0.0    1.4e-08   34.7   0.0    1.6  1  DJ-1_PfpI  DJ-1/PfpI family
  ------ inclusion threshold ------
      0.043   13.5   0.0       0.14   11.8   0.0    1.9  1  ThiJ_like  ThiJ/PfpI family-like
      0.079   13.3   0.0       0.88   10.0   0.0    2.1  2  Ntox1      Putative RNase-like toxin, toxin_1
       0.16   11.9   0.0       0.49   10.3   0.0    1.8  2  PASTA      PASTA domain


Domain annotation for each model (and alignments):
>> DJ-1_PfpI  DJ-1/PfpI family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.7   0.0   3.2e-12   1.4e-08      14     164 ..      30     234 ..      24     235 .. 0.80

  Alignments for each domain:
  == domain 1  score: 34.7 bits;  conditional E-value: 3.2e-12
                 HHHHHHHHHHHHTTEEEEEEESS..................TSEEEETTSEEEE-SEEGG............GCTCCG-SEEEE--BHHHHHHHHTSHH CS
   DJ-1_PfpI  14 vElivpvdvlkragikvdvvsvd..................keevkgsrGlkvtvdasld............dvkaaeyDalvlpGGragperlrenek 82 
                  E+  p++vl +ag++vd+vs +                  +        lk+  d++ d            dv+ ++y +     G+a+  +  +   
  EEA18742.1  30 SEALHPYHVLTAAGFEVDLVSETgtyiadwlsqqpdflngdD--------LKTWNDKTSDfrkkmdnmpkaaDVDGSQYGVFFASAGHASLIDYPKARN 120
                 58999******************9***999977666665430........444444444444444466667899999***********9988888899* PP

                 HHHHHHHHHHTT-EEEEETTTHHHHHH.......TTTTTTSEE--SGGGH.......HHHHHTTSEE-SS..................SEEEETTEEEE CS
   DJ-1_PfpI  83 vvelvkefaekgklvaaICagpqlLaa.......agvlkgrrvTsypavk.......dklekagakyvdk..................rvvvdgnlvTs 149
                 +++++ e+  +g++++++C+gp + a+       + v+kg+++T++++         d+l+  +++ v++                    vvdg+lvT 
  EEA18742.1 121 LQKIAEEVWANGGVLGSVCHGPAIFANildkatgEPVIKGKKLTGFTTEAeytmqimDDLKSWNSELVEElaarlgakyersagiwddFHVVDGRLVTG 219
                 **********************888764333333469*******99875533333445568888888888999999999999***99999********* PP

                 SSGGGHHHHHHHHHH CS
   DJ-1_PfpI 150 rgpgaaiefalelle 164
                 ++p +a   a++++e
  EEA18742.1 220 QNPASATSTAKAVVE 234
                 *****9999999887 PP

>> ThiJ_like  ThiJ/PfpI family-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   3.2e-05      0.14       4      34 ..      25      59 ..      23     177 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3.2e-05
   ThiJ_like  4 eGydvtevaipwkvlkdagfsveFvtekgk....v 34
                +G  + e+  p++vl+ agf+v+ v+e+g+     
  EEA18742.1 25 TGVFISEALHPYHVLTAAGFEVDLVSETGTyiadW 59
                67888999********************9864442 PP

>> Ntox1  Putative RNase-like toxin, toxin_1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0    0.0002      0.88      46      89 ..      68     135 ..      60     138 .. 0.86
   2 ?    0.9   0.0      0.13   5.9e+02      44      58 ..     174     188 ..     167     223 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.0002
       Ntox1  46 addelkeeneevealRkldakl..aad......................eaakLiqaletarlnggka 89 
                 + d+lk +n++    Rk   ++  aad                      +a++L++  e++ +ngg +
  EEA18742.1  68 NGDDLKTWNDKTSDFRKKMDNMpkAADvdgsqygvffasaghaslidypKARNLQKIAEEVWANGGVL 135
                 679**********9998654432277799***********************************9965 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.13
       Ntox1  44 laaddelkeeneeve 58 
                 ++  d+lk +n e+ 
  EEA18742.1 174 MQIMDDLKSWNSELV 188
                 556789999998864 PP

>> PASTA  PASTA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       0.8   3.6e+03      18      30 ..      39      51 ..      38      57 .. 0.74
   2 ?   10.3   0.0   0.00011      0.49       2      53 ..     176     230 ..     175     236 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.8
                HHHTT--CCCEEE CS
       PASTA 18 LkalGlkiktvee 30
                L+a+G+ +  v e
  EEA18742.1 39 LTAAGFEVDLVSE 51
                8999997666665 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00011
                 E--TTTTSBHHHHHHHHHHTT--CCCEEE..ECTCCGTTB.EEEECS-TTSEECT CS
       PASTA   2 tvPdvtGmsvdeAkatLkalGlkiktvee..tsddvpeGt.VisQsPeaGtevsk 53 
                 ++ d++ ++ + +++++  lG k+  +    ++  v +G+ V++Q+P++ t++ k
  EEA18742.1 176 IMDDLKSWNSELVEELAARLGAKYERSAGiwDDFHVVDGRlVTGQNPASATSTAK 230
                 799*******************9999999*******************9999854 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (239 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       468  (0.026103); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.32s 00:00:00.85 Elapsed: 00:00:00.50
# Mc/sec: 1438.34
//
Query:       EEA18743.1  [L=726]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-21   76.9   1.5    1.9e-21   76.3   1.5    1.3  1  Fungal_trans  Fungal specific transcription factor domain
    1.1e-07   31.8  11.2    1.8e-07   31.1  11.2    1.3  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.021   13.2   1.2       0.26    9.6   0.8    2.0  2  CCD48         Coiled-coil domain-containing protein 48
      0.029   13.8   0.1      0.062   12.7   0.1    1.5  1  Not3          Not1 N-terminal domain, CCR4-Not complex compon
       0.08   11.2   0.6       0.12   10.7   0.6    1.2  1  CCCAP         Centrosomal colon cancer autoantigen protein fa
       0.12   12.8   0.3        2.7    8.4   0.4    2.6  2  Csm1_N        Csm1 N-terminal domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.3   1.5   6.5e-25   1.9e-21       1     265 [.     203     466 ..     203     468 .. 0.77

  Alignments for each domain:
  == domain 1  score: 76.3 bits;  conditional E-value: 6.5e-25
  Fungal_trans   1 ldrffsnfh.pqfpilhkpsflpkt.ssenssksayasplll.lailalGalfsesetkesnssltses.......qefiafplraeilihedfssp 87 
                   ++ f++  h ++fpi+++ +f +++ s + ++ +   +++l+ ++i +  ++++++  +es+  l + +        +++    r ++l+ ++++sp
    EEA18743.1 203 INFFWQTHHtSLFPIIDEANFKKHYqSLWVTGGTERRPSALVdIVIAMCMQYYLSTLPSESQGILVEGKdamvagrWHYW----RGQTLLTHELESP 295
                   578***********************999999999999999965555555666666676666666555566676665556....9999995555555 PP

  Fungal_trans  88 ssslwilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlp 184
                     s+ +lq+ ll+++y+ + s  +  e+ +++ vr a++lgLh +p+++        +e ++e+rrRlwwa++ +D    +klGrp++l+ds +   
    EEA18743.1 296 --SISTLQCHLLCAIYLCGGSFHNRMENSVSLSVRTAYTLGLHLDPPSNM-------PERDREMRRRLWWAVYLMDSKAGMKLGRPFMLHDSYVMPC 383
                   ..569****************9************************9976.......6666**************************99*****999 PP

  Fungal_trans 185 LPcddddlwesddaseetlvetklsneeksrkiasfllaLkkilskiagsllsiekqlqqrdlq...seklswveeleraldnW 265
                   LP+d+  +  + + s++  ++++    +++   ++   a+     ++++ +l + ++ ++ d     + + + + +++ +l++W
    EEA18743.1 384 LPNDSL-EAAAISGSTFAPIGDNATWLSFNLYQTKLYMAVRAAYTSFYDRILHLQHDQSIWDDPdtlQASAEALARHTQRLQQW 466
                   998877.77777777777777554444444444444555555555566666666666666665577777777777888888887 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.1  11.2   6.2e-11   1.8e-07       1      34 [.      27      58 ..      27      64 .. 0.91

  Alignments for each domain:
  == domain 1  score: 31.1 bits;  conditional E-value: 6.2e-11
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfys 34
                +aCd+Cr +++KCd k P Cs+C  ++l+C+ +s
  EEA18743.1 27 RACDECRMRRTKCDNKVP-CSKCSIKGLDCS-NS 58
                69****************.***********9.76 PP

>> CCD48  Coiled-coil domain-containing protein 48
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.8   8.7e-05      0.26     232     328 ..      12     108 ..       2     135 .. 0.74
   2 ?    1.7   0.0     0.021        63     286     322 ..     454     490 ..     450     497 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 8.7e-05
       CCD48 232 epeaaarelrqaqgalaaaeararrlrrgq.aevrrraeearqavlrslkrvrelealarqvpslqrlvrrleaelrryrsegsqlptparaspepgd 328
                    a+ r  ++aq a a  e r rr++ ++ +   + + +  +   +++ +   l     ++  l++ v++lea++ r r++  +l t +++s   g 
  EEA18743.1  12 RQTAPQRLRKRAQVARACDECRMRRTKCDNkVPCSKCSIKGLDCSNSGIPKASTLSEARDEITWLKQRVQQLEAQVDRQRNDSDNLTTSTNSSRS-GS 108
                 4444555567788888888888888886641444555567788999999999999999999*************************998887754.33 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.021
       CCD48 286 ealarqvpslqrlvrrleaelrryrsegsqlptpara 322
                 ealar+   lq++v  +   lr+ rs++ +  +   +
  EEA18743.1 454 EALARHTQRLQQWVDSVPEPLRSKRSNNGTPFSTDGT 490
                 9*************************99775555555 PP

>> Not3  Not1 N-terminal domain, CCR4-Not complex component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.1   2.1e-05     0.062     116     159 ..      64     108 ..      34     126 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.1e-05
        Not3 116 pkekekeearewlkdaideLneqvekleaeieklsskkkkkkk.s 159
                  + +e+++ ++wlk+ +++L+ qv++ + + ++l+++++ +++ s
  EEA18743.1  64 STLSEARDEITWLKQRVQQLEAQVDRQRNDSDNLTTSTNSSRSgS 108
                 4456788999************************99887776533 PP

>> CCCAP  Centrosomal colon cancer autoantigen protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.6   3.9e-05      0.12     545     591 ..      56     103 ..      12     106 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 3.9e-05
       CCCAP 545 sisneakaqalqaqqre.qeltqklqqmeaqhdkteneqdslltsqnt 591
                 s s   ka +l   + e   l q++qq+eaq d+  n+ d l ts n+
  EEA18743.1  56 SNSGIPKASTLSEARDEiTWLKQRVQQLEAQVDRQRNDSDNLTTSTNS 103
                 5555568888876666625699***********************997 PP

>> Csm1_N  Csm1 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   0.4   0.00091       2.7      34      65 ..      64      95 ..      60      99 .. 0.85
   2 ?    0.9   0.0       0.2     6e+02      21      34 ..     151     164 ..     148     179 .. 0.87

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00091
      Csm1_N 34 qkletkdqeiesLkeqlaeleekvkeleerrk 65
                 +l+   +ei  Lk+++++le++v+++ ++++
  EEA18743.1 64 STLSEARDEITWLKQRVQQLEAQVDRQRNDSD 95
                56778889****************99987765 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.2
      Csm1_N  21 lvsklvhENsvLsq 34 
                  v++l++EN +L++
  EEA18743.1 151 FVQRLTKENKLLDR 164
                 599********986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (726 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       952  (0.0530983); expected 358.6 (0.02)
Passed bias filter:                      724  (0.0403815); expected 358.6 (0.02)
Passed Vit filter:                       109  (0.00607954); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.76u 0.30s 00:00:01.06 Elapsed: 00:00:00.47
# Mc/sec: 4633.28
//
Query:       EEA18744.1  [L=501]
Description: cytochrome P450 oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-72  245.2   0.0    1.5e-72  244.9   0.0    1.0  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  244.9   0.0   8.2e-77   1.5e-72       9     461 ..      47     496 ..      40     498 .. 0.89

  Alignments for each domain:
  == domain 1  score: 244.9 bits;  conditional E-value: 8.2e-77
                 CCHCHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGH.HHHHHHHHHHHHHH CS
        p450   9 lvgnllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfang.ekwkklRrfltptl 106
                  +++l+++  ++++  v + l+kkygp++r+ ++   v  + +p  +k +++++++++++ +++a++       ++ +++ ++  +++  +Rr +  + 
  EEA18744.1  47 RLWYLKKIF-EGKFELVNVALHKKYGPVVRIAPN---VYSIDDPGCAKTLYGHGSKFVKASWYSAWMPL---DINKASLFGDTDpHHHALQRRKFASSY 138
                 556666665.588889999************997...55678899***********************8...666777776666677788888888888 PP

                 TSHSTT.THHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCCCH.HHTCCSC CS
        p450 107 tsfgkl.sleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelssllskssvqllllfp.llkylpt 203
                  +  +l  +e++v+ +++ + ++l + a+  +++d++++++++a+dvig+i+Fg+rf+ l+ + +++  +a+++ + l  +++   + lfp +l+ ++ 
  EEA18744.1 139 SMT-SLvGYEPFVNNCTKVFTNRLSEIAKLDETIDLAHWFQCYAFDVIGKITFGRRFGFLDYSTRTDVFDAIDTRN-LY-STF---VGLFPsWLHRMLF 231
                 888.999**********************************************************9*****99994.44.344...4444448888888 PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHHCHCHC....SCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHH CS
        p450 204 kllrklkeavkklkdlldklieerretldsa....kksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqek 298
                 +ll +   +  ++ ++++  i  r++ l+s      + + df++ + + + e++  ++++++++ + +   ++aG+dTt+  ls + y+L+k+Pe+  +
  EEA18744.1 232 PLLPTTGGH-GYVGKYTMDEIASRESLLKSPdvkeREGKPDFVSRFFQIR-EEDP-ENMTKTDIFTMCQSNIGAGSDTTAISLSEIVYNLLKHPETYTR 327
                 888888877.88999999999999999999989887799**********8.5555.59***************************************** PP

                 HHHHHHHHCCTTT...T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS.CEEETTEEE-TT-EEEEEHHHHHT-TTTS.SSTTS--GGGGB-TT CS
        p450 299 lreEidevlgdkr...eptyddlqklpyldavikEtLRlhpvvplllpRevtk.dvvirgylipkGtevivnlyalhrdpevf.pnPeeFdpeRFldek 392
                 l++Eide+  + +   ++++++ q+lp+l+avikE+L lh+++ l l R+v++    + g  +p+G +v +n +  hr+ ++f  ++++ +peR+lde 
  EEA18744.1 328 LKKEIDEAASQGKiadPISFKETQELPFLQAVIKEALWLHSATGLPLARVVPEgGAMFAGKQFPAGATVGINSWVAHRNTNIFgADADSWRPERWLDEH 426
                 *********8888899*************************************99*******************************************9 PP

                 S.CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGEEESSCSSEEESSSSEE CS
        p450 393 g.nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdpppileksglllppkpikl 461
                   +    + +fl+FG G R C+G++l ++e++ ++ +lL++F++ l+++ + ++ + k+   ++p+ +++
  EEA18744.1 427 SnDVAEMDRYFLAFGLGSRTCLGKNLSMLEMSKLIPQLLRTFDFVLDEKLRFKDWDTKNRWFVKPQDFYV 496
                 964557899***************************************9999999999855555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (501 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       417  (0.0232584); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.56
# Mc/sec: 2690.86
//
Query:       EEA18745.1  [L=328]
Description: mitochondrial carnitine:acyl carnitine carrier, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.1e-58  195.2   5.4    1.6e-19   69.6   0.4    3.1  3  Mito_carr  Mitochondrial carrier protein


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.6   0.4   8.9e-24   1.6e-19       6      93 ..      29     113 ..      25     117 .. 0.93
   2 !   69.6   0.0   9.2e-24   1.6e-19       4      94 ..     129     223 ..     126     226 .. 0.89
   3 !   57.5   0.2   5.2e-20   9.3e-16       2      96 ..     234     322 ..     233     323 .. 0.95

  Alignments for each domain:
  == domain 1  score: 69.6 bits;  conditional E-value: 8.9e-24
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHH.HGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   6 lkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGl.rglyrGllpnllrvapasalkfvlyetlkrll 93 
                 l++++aGg++g++a+++ +P+d+vK+r+qt++k   +    +++dv++k++  eGl rgly G+++ l++v+p  a+ f+ y+  k+l+
  EEA18745.1  29 LRSFIAGGVGGICAVVIGHPFDLVKVRMQTAEKGVYT----GAMDVVRKTIAREGLaRGLYAGVSAPLVGVTPMFAVSFWGYDLGKTLV 113
                 689****************************999665....39*************99*************************999987 PP

  == domain 2  score: 69.6 bits;  conditional E-value: 9.2e-24
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSS....HHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
   Mito_carr   4 svlkellaGglagavatlvttPldvvKtrlqtqkksskksksaa....ildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlll 94 
                 s+++  +aG+++++  tl+t+P+++vK+ lq+q+++   +++++     +dv++++yke Glr+ +rG  ++l r ap sa++f++ye++kr l+
  EEA18745.1 129 SIAQISAAGAFSALPMTLITAPFERVKVLLQIQGQNPPPAGQKPkysgGVDVVRQLYKEGGLRSVFRGSAMTLARDAPGSAAYFAAYEYIKRSLT 223
                 6677789*************************9999555444445555********************************************986 PP

  == domain 3  score: 57.5 bits;  conditional E-value: 5.2e-20
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCTT CS
   Mito_carr   2 elsvlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlllkk 96 
                 +ls+++ + aGg+ag++ ++ ++P+d+vK r+q+++++ +      i  +++ i  + G+++++ G++p+l r +pa+a++f+  e  ++ ++k+
  EEA18745.1 234 DLSLTAVVTAGGAAGIAMWIPVFPVDTVKSRMQSAPGKVT------IGGTIRAIHASGGFKAFFPGFGPALARAVPANAATFLGVELAHKAMNKM 322
                 56788899******************************77......899***************************************9999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (328 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       397  (0.0221429); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.30s 00:00:00.81 Elapsed: 00:00:00.48
# Mc/sec: 2050.93
//
Query:       EEA18746.1  [L=1120]
Description: integral membrane protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.9e-40  136.9  26.5    1.4e-33  116.3  20.9    2.3  2  TRP       Transient receptor potential (TRP) ion channel
    1.1e-21   77.7   0.0    1.6e-21   77.1   0.0    1.3  1  TRP_N     ML-like domain


Domain annotation for each model (and alignments):
>> TRP  Transient receptor potential (TRP) ion channel
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   0.2   2.3e-09     2e-05      30      80 ..     271     321 ..     227     324 .. 0.76
   2 !  116.3  20.9   1.6e-37   1.4e-33     130     399 ..     341     603 ..     332     614 .. 0.84

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 2.3e-09
         TRP  30 aaahvaasvlslflyfQsvafigmlsvnyPpvlaawtqnfaWsmglirvsf 80 
                 ++  v+  + + + y+Q+++++g+ls++yP+ +++ ++  aWs++++++sf
  EEA18746.1 271 LLRLVTPGFADCLQYIQFIVLTGALSLSYPGYYQPVVSSGAWSILMFNHSF 321
                 666777779999***********************************9997 PP

  == domain 2  score: 116.3 bits;  conditional E-value: 1.6e-37
         TRP 130 vrGikrvaekagiestnafmtgll.ffliliallvv...lvllfKlllellarkklikedrlkefrknwlgilkgallrlilifffqllvlclfeftqr 224
                 ++G+ r+ ++ g es  ++++g + ++l+++ +++v   + + f ++ + +ar+    e++l+   kn   +++ ++  ++  f  + + l+l++++  
  EEA18746.1 341 THGLDRLRQYIGLESIRDVWPGSIiWLLVILSAVTVltqIAFGFQWIYHRMARV---LEEDLRS--KNVPFTIGNTIRITFNFFLLPTVSLALYQLVIA 434
                 36*******************999788888888888666666677776655555...5888886..99*****************************76 PP

         TRP 225 dsaavvvlAvillalflgvllffafrvlitarkskrlhknpaylLysdkkvlnkyGflyeqyrasrywffvpllvylfvkalfialaqgsGkvQviall 323
                   + + v+A  +++++  +llf+++ + +++    r        L++d +++  yG ly+ yr +   f ++ ++++f++a+ i+++q sG++Qv++l 
  EEA18746.1 435 GHSTAYVVALAVILIVA-LLLFALWMIRLIISARPRA------YLFDDLSTVLLYGPLYNTYRDDVAPFALVPIFITFLRAIAIGALQPSGVAQVVLLA 526
                 65555555555554444.4477777777777774454......7******************************************************* PP

         TRP 324 iiEllylvlliwlrPyed.krtnvlniiisvvkvlnvilllaFseefglseivktvvGvvlivinavlalvllilii 399
                 i+E++++ ll+ +rPy +  + n+ + ++s+v++l+v+l++aF+ ++g+se +k+ +G+ ++v+++ + ++ ++l +
  EEA18746.1 527 ICEVAMILLLVAFRPYASpTSMNLYQLVFSFVRFLVVLLSVAFVPSLGISEQTKGWIGYAILVLHGGMLVFGFFLNA 603
                 ****************98456788888**************************************977666555544 PP

>> TRP_N  ML-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.1   0.0   1.8e-25   1.6e-21       2     138 ..      65     222 ..      64     223 .. 0.87

  Alignments for each domain:
  == domain 1  score: 77.1 bits;  conditional E-value: 1.8e-25
       TRP_N   2 vtssfenClens........qftaskfdvtftpdnk......tvvfnvtgt........ssienkavtlelkveaygyevvnetvdpCdanvkglCPlg 78 
                 ++++f+nCle +        qf++++f+v+++p         ++++nvtg         ++ ++ ++tl+++++++++++++ ++++C++  +g+CPlg
  EEA18746.1  65 AFINFDNCLETNivndpshlQFVPKFFSVVYDPAPGpnpldiVIYGNVTGDgeivdivdNNGNKTYTTLFTTLDVLTFTPYEHPTEFCQNVTQGTCPLG 163
                 6899****665556667899***********77666668888****************96666667********************************* PP

       TRP_N  79 pgfkinasgvlkvseevvseipsi........aYsipdldatvrvriystgeateiaCvsatitngkt 138
                 p+f++n s     ++   s+++++        ++++++l at+r+ ++ + + t+++Cvs  it++++
  EEA18746.1 164 PVFNVNGS-----DP---SQLRAFtvqhelgtSFQLASLVATLRI-KSGDPAGTDLGCVSGIITPDLG 222
                 **999999.....45...67777777777777*************.5545599*************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1120 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       710  (0.0396006); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.79u 0.30s 00:00:01.09 Elapsed: 00:00:00.50
# Mc/sec: 6795.47
//
Query:       EEA18747.1  [L=203]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (203 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       879  (0.0490267); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.27s 00:00:00.69 Elapsed: 00:00:00.42
# Mc/sec: 1434.67
//
Query:       EEA18748.1  [L=385]
Description: hypothetical protein PMAA_010300 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.9e-13   49.2   0.2    8.9e-13   48.4   0.2    1.4  1  Methyltransf_23  Methyltransferase domain
    3.9e-08   33.9   0.0      1e-07   32.6   0.0    1.7  1  Methyltransf_25  Methyltransferase domain
      1e-06   29.4   0.0    2.3e-06   28.2   0.0    1.6  1  Methyltransf_12  Methyltransferase domain
    0.00022   21.8   0.0    0.00067   20.3   0.0    1.8  2  Methyltransf_11  Methyltransferase domain
  ------ inclusion threshold ------
      0.045   13.5   0.0      0.087   12.6   0.0    1.4  1  Methyltransf_31  Methyltransferase domain
      0.051   13.0   0.0      0.093   12.2   0.0    1.4  1  Methyltransf_4   Putative methyltransferase
      0.055   12.8   0.0      0.096   12.0   0.0    1.3  1  Methyltransf_2   O-methyltransferase domain
      0.068   12.7   0.0       0.12   11.9   0.0    1.4  1  MTS              Methyltransferase small domain


Domain annotation for each model (and alignments):
>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.4   0.2     4e-16   8.9e-13       8     164 ..      70     272 ..      64     273 .. 0.71

  Alignments for each domain:
  == domain 1  score: 48.4 bits;  conditional E-value: 4e-16
  Methyltransf_23   8 elsdklerllpklraggrvLdiGcGtGillevlrengf..svtgvDlspeaveiaekakkaqkdqfdeqeaae........pqgkfdlIvlrev 91 
                       l + ++ l+p  +++  vLdiG+G G +++ +++     ++ g Dlsp+ ++ a ++++  ++  d     +          + fdlI+ r +
       EEA18748.1  70 LLLQDRLYLAP-IPQPHHVLDIGTGIGLWASNISDAHPttQILGTDLSPIWHDDALTRPNLTFEVDDC----CsnwtyldeGRELFDLIHIRCL 158
                      55566777777.89999****************77643369*********999875444444444411....122334443666********** PP

  Methyltransf_23  92 lehvpdppellrqiatllkpg.Gylllseplasl.......................................kedrllld....w.lylvpag 140
                       ++v+d+ +l +q++++l pg G ++  e+  sl                                       ++d    +    w +++ + +
       EEA18748.1 159 YGSVKDWRKLYQQAFEHLVPGkGFIEQIEV--SLvprfwytagdtrevgndfsqlwdmgwdcdstaadfardnSSD----SifvmWyRFWQECS 246
                      *********************9*9987775..34445778888888777666666666666666555554444344....15554556666666 PP

  Methyltransf_23 141 rhi..sffsarslkelleeaGlevve 164
                      r     +f a++++ l  e G+++v 
       EEA18748.1 247 RRTgkTWFVADQMASLIYEVGFDNVC 272
                      43345999999999999999999986 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.6   0.0   4.5e-11     1e-07       1      96 [.      87     179 ..      87     179 .. 0.86

  Alignments for each domain:
  == domain 1  score: 32.6 bits;  conditional E-value: 4.5e-11
                      EEEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHHTTTTEEEEESBC....CGBSSSTTTEEEEEEESTGGGSSHHHHHHHHHHHH CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlgkakvtgvDiseemleaareraeeeglnvefvqgda....edlpfedgsfDlvvssgalhhlsdedlekalkeia 90 
                      vLd+G+G G ++ +++++ +  +++g+D+s+   + a +r      n++f++ d+    + l++  + fDl++++ +l + s +d++k++++++
       EEA18748.1  87 VLDIGTGIGLWASNISDAHPTTQILGTDLSPIWHDDALTRP-----NLTFEVDDCcsnwTYLDEGRELFDLIHIR-CL-YGSVKDWRKLYQQAF 173
                      9*****************989***************99998.....778877777522244778888*******6.53.55678********** PP

                      HHEEEE CS
  Methyltransf_25  91 rvLkpg 96 
                      ++L pg
       EEA18748.1 174 EHLVPG 179
                      ***998 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.2   0.0     1e-09   2.3e-06       1      96 [.      88     179 ..      88     182 .. 0.82

  Alignments for each domain:
  == domain 1  score: 28.2 bits;  conditional E-value: 1e-09
  Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvelealdlldldggssfDlvvasnvlhhlkdirevldnirklLk 94 
                      L+iG+G G  ++ + +++p+++++g+D+sp   +da ++ +   + +  + +++ ld +    ++ fDl+++ ++   +kd+r++ +++ ++L+
       EEA18748.1  88 LDIGTGIGLWASNISDAHPTTQILGTDLSPIWHDDALTRPNLTFEVDDCCSNWTYLDEG----RELFDLIHIRCLYGSVKDWRKLYQQAFEHLV 177
                      8******************************9966666644444334344444444433....249**************************** PP

  Methyltransf_12  95 pg 96 
                      pg
       EEA18748.1 178 PG 179
                      *8 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0     3e-07   0.00067       1      91 [.      88     179 ..      88     183 .. 0.85
   2 ?   -3.1   0.0       5.7   1.3e+04      58      68 ..     227     237 ..     215     247 .. 0.60

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 3e-07
                      EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-..EEEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHHHEEE CS
  Methyltransf_11   1 LdvGcGtGrlaealakrg..arvvgvDlskemlklakekaseegl..kvefvvadaeklpfednsfDlvvssevlhhvedpekalkeiaRvLkp 90 
                      Ld+G+G G+ a  + ++   ++++g+Dls+  ++ a     +++l  +v+  +++ + l    + fDl+ ++     v+d++k+ +++   L p
       EEA18748.1  88 LDIGTGIGLWASNISDAHptTQILGTDLSPIWHDDAL---TRPNLtfEVDDCCSNWTYLDEGRELFDLIHIRCLYGSVKDWRKLYQQAFEHLVP 178
                      8**************88889*************7773...333322245557888888999999************************999999 PP

                      E CS
  Methyltransf_11  91 g 91 
                      g
       EEA18748.1 179 G 179
                      8 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 5.7
                      -TT-EEEEEEE CS
  Methyltransf_11  58 ednsfDlvvss 68 
                      +dns D +++ 
       EEA18748.1 227 RDNSSDSIFVM 237
                      45666666554 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   3.9e-05     0.087       6     108 ..      86     183 ..      82     204 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 3.9e-05
  Methyltransf_31   6 rvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielArenaqklgldnveFeqgdieeleklledekfDlilsnevlnaladpdkileeier 99 
                      +vlD+G+G G  + ++   + p  ++ G D s+     A ++  +l ++ v  + ++++ l+    +e fDli+ +++   ++d  k ++++++
       EEA18748.1  86 HVLDIGTGIGLWASNIS-DAHPTTQILGTDLSPIWHDDALTR-PNLTFE-VDDCCSNWTYLD--EGRELFDLIHIRCLYGSVKDWRKLYQQAFE 174
                      79********9999999.88999**********999999996.444443.555557777777..67899************************9 PP

  Methyltransf_31 100 vlkpggill 108
                       l pg  ++
       EEA18748.1 175 HLVPGKGFI 183
                      999998876 PP

>> Methyltransf_4  Putative methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   4.2e-05     0.093       4      36 ..      86     118 ..      83     130 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 4.2e-05
                     EEEEET-TTSHHHHHHHHHSTTSEEEEEES-HH CS
  Methyltransf_4   4 vvleiGcGkGeflvalAkknPdknflGiEirvk 36 
                      vl+iG+G G + ++++ ++P++++lG +++  
      EEA18748.1  86 HVLDIGTGIGLWASNISDAHPTTQILGTDLSPI 118
                     589************************988765 PP

>> Methyltransf_2  O-methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   4.3e-05     0.096      38      96 ..      59     117 ..      50     133 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 4.3e-05
                     HHHHHHHTTHHHHHHHHHHSS-GGG-SEEEEET-TTSHHHHHHHHH-TT-EEEEEE-HH CS
  Methyltransf_2  38 kfnkglqessslvakkvleafdleglkslvDvGGGtGalakaivsayPtikvivfDlpe 96 
                     + ++ +++ ++l  ++ l    + + ++++D+G G+G  a +i+ a+Pt +++  Dl+ 
      EEA18748.1  59 QTMSKMHSIKELLLQDRLYLAPIPQPHHVLDIGTGIGLWASNISDAHPTTQILGTDLSP 117
                     5677888999999999999999999999************************9999975 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   5.4e-05      0.12      21      64 ..      75     116 ..      50     132 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 5.4e-05
                 HHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESB CS
         MTS  21 klLletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvd 64 
                 +l l  +p  + ++vlD+G+G+G+ + ++ +++p++++  +d +
  EEA18748.1  75 RLYLAPIP--QPHHVLDIGTGIGLWASNISDAHPTTQILGTDLS 116
                 33333444..4667*********************999988865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (385 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       450  (0.025099); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2611.75
//
Query:       EEA18749.1  [L=92]
Description: molybdopterin synthase small subunit CnxG [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.7e-05   23.1   0.0    0.00076   20.1   0.0    1.9  1  ThiS      ThiS family


Domain annotation for each model (and alignments):
>> ThiS  ThiS family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   0.0   4.2e-08   0.00076       1      75 [.       6      90 ..       6      92 .] 0.84

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 4.2e-08
                EEETTCCHHHHTCEEEEESSTSBHHHHHHHHHHHTCHHG..TTTTEEEEETTEEEGC.CT.......TTSB--TTCEEEEEESTT CS
        ThiS  1 vllfaelrelageeelelaegstvaelleaLgerypela..lerrvavavNgeivpr.lw.......ldtelkdgDevailppVa 75
                +l+fa++   +g++ + l+ +  ++ l+  L+eryp+++      + v v  e+v+  ++       ++ ++ +g evai+ppV+
  EEA18749.1  6 ILYFASASSYTGKSSEALPAPLPLSRLFPLLEERYPGITekVLGSCSVSVGLEYVDIpDGpaagnevDERVIGEGEEVAIIPPVS 90
                79**********999**************************7788999998888886555222222257788************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (92 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       143  (0.0079759); expected 358.6 (0.02)
Passed bias filter:                      135  (0.0075297); expected 358.6 (0.02)
Passed Vit filter:                         7  (0.000390429); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.36u 0.26s 00:00:00.62 Elapsed: 00:00:00.41
# Mc/sec: 668.02
//
Query:       EEA18750.1  [L=395]
Description: cystathionine gamma-synthase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.3e-60  203.7   0.0      9e-60  202.2   0.0    1.7  1  Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
     0.0054   15.7   0.0     0.0072   15.3   0.0    1.2  1  Aminotran_5      Aminotransferase class-V
     0.0066   15.7   0.0      0.012   14.8   0.0    1.4  1  Aminotran_1_2    Aminotransferase class I and II


Domain annotation for each model (and alignments):
>> Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  202.2   0.0   1.5e-63     9e-60       2     382 .]      10     391 ..       9     391 .. 0.86

  Alignments for each domain:
  == domain 1  score: 202.2 bits;  conditional E-value: 1.5e-63
                      HHHHHTTTTCHTTTTBSS--B---SBBBESSHHHH........CTTCSSS...-SBTTT--HHHHHHHHHHHHHHT-SEEEEESSHHHHHHHHH CS
  Cys_Met_Meta_PP   2 Tllvhagqekdeqtgavavpiyltstykfkdvdea........fageekg...yeYsRsgnptrsvleeriaaLeggeaalavssGmaAiaaai 84 
                      Tl+vha+   + + + va+pi+l++t+++++  ++        f +e+      +YsR+  p++  +e+ ++ L +g +ala+ sG+aA++ a+
       EEA18750.1  10 TLAVHADDVVN-NATDVAPPIHLSTTFRYRKNPDElipaaehnFDEEDPTtmePIYSRVAAPNSARFEAILSSLLKG-RALAYGSGLAALNGAL 101
                      999***99987.7899*************98766678888887444444322368*********************9.589*********5444 PP

                      HTTS-TTEEEEEESTSSHHHHHHHHHTHHHTTCEEEEESTTSHHHHHHHCCTTEEEEEEESS-TTTT----HHHHHHHHHHTT-EEEEEGTTTH CS
  Cys_Met_Meta_PP  85 lallkaGdeivvsddlYggtqrllkkvlkklgievkfvdtsdleelekaikentklvylEtptnpllkvvDiekiaklakkagvlvvvDntfas 178
                        ll+   + ++  d Y g++ +++ + + +g++    d+  +eel+       ++++lEtp np     Die+ a+ a+++g+ ++vD tf  
       EEA18750.1 102 -VLLN--PKNISIGDNYHGCHGVIEIFNRLTGLKKLGLDCP-AEELH-----AGDVILLETPLNPNGTAFDIEHYAQKAHSRGAFLIVDSTFGP 186
                      .4443..466899999*********99999***99999994.44444.....4699************************************** PP

                      TTTS-GGGGT-SEEEEETTTTTTCSSS--EEEEEESSCHHHHHHHHHHHHHHT-B--HHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHTS.. CS
  Cys_Met_Meta_PP 179 pllqrplklgaDivvhSaTKylgGhsdvvaGvivvkgkeelkkelkflqnalGavlspfdawlllrGlkTLslRlerhqenAlkvAefLekh.. 270
                      p lq p+++gaDi++hS++Ky gGhsd++ Gv+++   +++ ++l     +lG+ +   ++wl +r l+TL+lR++r+++nA  + +fL++   
       EEA18750.1 187 PGLQDPFEFGADIIMHSGSKYFGGHSDLLCGVLATRR-KDWFDQLFGQRLHLGNNMGNLESWLGVRSLRTLELRVQRASQNATSLVSFLHSAlt 279
                      **********************************888.88888899999****************************************99877 PP

                      ..........TTEEEE....E-TTSTTSTTHHHHHHHSSSG-S.EEEEEESSHHHHHHHHHHC-SSSEECSS-SSSS-EEEETTTTTTTTSCHH CS
  Cys_Met_Meta_PP 271 ..........pkvekv....yYpglpshpqhelakkqlkgagg.vlsFelkseeekakkfvdnlklfslaeslGgveslielpasmthasipke 349
                                ++v+kv    ++++l+++p   ++kkq+ ++ g v+s  +k+e + a+++ ++l+ f +a+slGgveslie  a+         
       EEA18750.1 280 qsnaaagsdaETVSKVlaeiRHASLQTEP---YVKKQMPNGYGpVFSIIMKDE-ALARRLPSKLQYFHHATSLGGVESLIEWRAMS-------- 361
                      77676666554666552222688777777...566777655555*******99.679***********************987643........ PP

                      HHHHTTS-TTEEEEE--SS-HHHHHHHHHHHHH CS
  Cys_Met_Meta_PP 350 ereaagvtddliRlsvGiEdvdDliaDlkqale 382
                         +  v ++l+R+svGiE+ +Dl +Dl  a++
       EEA18750.1 362 ---DPRVDQRLLRVSVGIEHWEDLRDDLVSAFK 391
                      ...4556779*******************9996 PP

>> Aminotran_5  Aminotransferase class-V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   1.2e-06    0.0072     150     204 ..     156     209 ..     145     302 .. 0.92

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 1.2e-06
                  TTTTEB--HHHHHHHHHHTT-EEEEE-TTTTTTS---HHHHTESEEEEETTTTTS CS
  Aminotran_5 150 nvtGtiqpveeigklakkkgalvlvDaaqavghipidvkklgvDflafsghKllg 204
                  n  Gt +++e+ ++ a+ +ga+++vD++ + +  + d  ++g+D+++ sg K++g
   EEA18750.1 156 NPNGTAFDIEHYAQKAHSRGAFLIVDSTFGPPGLQ-DPFEFGADIIMHSGSKYFG 209
                  778***********************999988876.8889************998 PP

>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   2.1e-06     0.012     142     198 ..     143     192 ..     124     230 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 2.1e-06
                    HHCTTETEEEEEEESS-TTT--B--HHHHHHHHHHHHHTTEEEEEEETTTTCBSSSS CS
  Aminotran_1_2 142 apegnkktkvilvesphNPtGtvatleeleklldlakkynlllfvDeaYagfvfgsl 198
                    +++g     vil+e+p NP Gt+++ e++ +    a++++++l+vD +++   ++++
     EEA18750.1 143 LHAG----DVILLETPLNPNGTAFDIEHYAQK---AHSRGAFLIVDSTFGPPGLQDP 192
                    4433....46*******************999...************9987666643 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (395 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       395  (0.0220313); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.23s 00:00:00.73 Elapsed: 00:00:00.39
# Mc/sec: 3029.00
//
Query:       EEA18751.1  [L=1190]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1190 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       566  (0.031569); expected 358.6 (0.02)
Passed bias filter:                      383  (0.021362); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.77u 0.30s 00:00:01.07 Elapsed: 00:00:00.46
# Mc/sec: 7762.92
//
Query:       EEA18752.1  [L=1061]
Description: mitochondrial exoribonuclease Cyt-4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.9e-45  153.8   0.0    1.3e-30  106.9   0.0    2.6  3  RNB       RNB domain


Domain annotation for each model (and alignments):
>> RNB  RNB domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0      0.26   4.7e+03     231     296 ..     414     477 ..     384     487 .. 0.59
   2 !  106.9   0.0     7e-35   1.3e-30       1     225 [.     556     834 ..     556     855 .. 0.87
   3 !   44.1   0.1   8.9e-16   1.6e-11     279     325 ..     859     906 ..     845     907 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 0.26
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         RNB 231 nekledliklakklglklednsskknlqeslekleeeeaeqllselllrllkeakyssepvgHfgL 296
                 ++++ ++  +a+  ++ ++d ++ + +q+++    ++  + +l+ l+  +++++++++++++  ++
  EEA18752.1 414 PTTMSNVGPSAQ--QYTMDDTPDGRVYQKVITDQFDDSDKIILEYLVHFSIPSQRLNMSSARYAAM 477
                 334444444444..3445566666667777777767776777777777777777777777554444 PP

  == domain 2  score: 106.9 bits;  conditional E-value: 7e-35
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         RNB   1 RkdlrdllvitIdpedakdlDdAisieklp..ngnyelgVhIADvshyvkegspldkearkratsvyLpekvvpMLPqelsedlcSLnpgedrlalsvl 97 
                 R+d  +l++++Id+++ak++Dd+is+e+    ++ ++l VhIA ++ +++ ++p+ k a+ r t+vyLpe+ + MLP++++++ +SL  +++ l++s+ 
  EEA18752.1 556 RVDWGELPIYCIDDPGAKEIDDGISLEPVAgtEDTFWLRVHIANPTAFMPHDDPISKNAAARLTTVYLPERHYSMLPTSFTSRSLSLAGNSPTLTISAK 654
                 88999**********************88886669************************************************9999999999999999 PP

                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..........................xxxxxxxxxxxxxxxxxxxxxxxxxxx.. RF
         RNB  98 idvdekgevlsveiylsvIkskarltydevqdlleqkdekeekk..........................taedLellyelakalrkkRlkkgalef.. 168
                 ++++  g vl+++i+++v +++ +lt   + ++l++  +++  +                          + e  +l++++   +++k +++g l    
  EEA18752.1 655 VNLN--GDVLETDITNGVARNVVYLTHAGLRNALKGHMKSS--QtytvgkdppshylqqlspespavtpeQSETFNLMRRIMTQINTKWRENGGLTWpd 749
                 9999..99**************************8777654..24689**********************9******************9**9999965 PP

                 xxxxxxxxxxxxxx..........................xxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         RNB 169 dspeikllldedkg..........................nrielkveeetk..ahslveelmllANelvArflseleipailri 225
                 ++++ + ++ + +                            +++++++e ++   + lv+ +m  A ++++r+ + ++ip ++ +
  EEA18752.1 750 NMSQQNPSIYSGNPippfsvhpdkfdweggyyqgdpsillPVSDVDPYEVPDlsQRNLVALVMRFACHVAGRWSADRNIPLVYDG 834
                 3555555555534477777777778999********999966667776665554789***********************99964 PP

  == domain 3  score: 44.1 bits;  conditional E-value: 8.9e-16
                 xxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         RNB 279 rllkeakyssep.vgHfgLaleeYthfTSPirRYpDlvvhrllkalla 325
                 ++ + + ys ++ ++H gL+++ Yt++TSP+rRY+Dlv h++++a+l+
  EEA18752.1 859 HFAPPKGYSASSvLPHSGLGVDAYTKATSPLRRYSDLVAHYQIEAALR 906
                 56677888888789*******************************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1061 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       616  (0.0343577); expected 358.6 (0.02)
Passed bias filter:                      554  (0.0308997); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.75u 0.31s 00:00:01.06 Elapsed: 00:00:00.45
# Mc/sec: 7092.87
//
Query:       EEA18753.1  [L=62]
Description: TOM core complex subunit Tom6, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0027   17.2   0.9     0.0038   16.7   0.1    1.7  2  Tom6      Mitochondrial import receptor subunit Tom6, fungal


Domain annotation for each model (and alignments):
>> Tom6  Mitochondrial import receptor subunit Tom6, fungal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.1      0.16   2.9e+03      22      28 ..      17      23 ..      17      24 .. 0.81
   2 !   16.7   0.1   2.1e-07    0.0038      19      45 .]      36      62 .]      31      62 .] 0.89

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 0.16
        Tom6 22 nvaLFva 28
                +++LF+a
  EEA18753.1 17 QAGLFGA 23
                6899997 PP

  == domain 2  score: 16.7 bits;  conditional E-value: 2.1e-07
        Tom6 19 vllnvaLFvaGVaFIqSpLmdmLaPqL 45
                ++    +F a VaF +S+L ++L P L
  EEA18753.1 36 IVRSIVIFSAAVAFFHSSLSEFLIPPL 62
                6667889*****************966 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (62 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       440  (0.0245412); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.29s 00:00:00.68 Elapsed: 00:00:00.44
# Mc/sec: 421.26
//
Query:       EEA18754.1  [L=589]
Description: DUF1716 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.1e-40  136.5   1.5    9.2e-40  135.0   0.2    2.4  2  CTNNBL         Catenin-beta-like, Arm-motif containing nuclea
    3.5e-05   23.7   0.1       0.12   12.4   0.0    3.2  3  Arm            Armadillo/beta-catenin-like repeat
     0.0012   17.3   0.2     0.0032   15.9   0.0    1.8  2  Neurochondrin  Neurochondrin
     0.0014   17.8   3.5      0.048   12.8   0.4    2.3  2  MMS19_C        RNAPII transcription regulator C-terminal
  ------ inclusion threshold ------
      0.029   13.8   2.3        0.1   11.9   1.8    2.2  3  Mo25           Mo25-like
       0.03   14.5   0.3        1.1    9.3   0.0    3.5  4  V-ATPase_H_C   V-ATPase subunit H
      0.031   13.8   1.1      0.084   12.4   0.1    2.2  2  Drf_GBD        Diaphanous GTPase-binding Domain
      0.043   12.9   0.8       0.09   11.9   0.8    1.5  1  PHTB1_C        PTHB1 C-terminus
      0.053   13.9   0.8       0.51   10.8   0.3    2.8  2  HEAT_2         HEAT repeats


Domain annotation for each model (and alignments):
>> CTNNBL  Catenin-beta-like, Arm-motif containing nuclear
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  135.0   0.2   4.6e-43   9.2e-40       2     104 .]      95     199 ..      94     199 .. 0.96
   2 ?   -1.0   0.1         1     2e+03      76      93 ..     314     331 ..     301     333 .. 0.80

  Alignments for each domain:
  == domain 1  score: 135.0 bits;  conditional E-value: 4.6e-43
      CTNNBL   2 eilelldeeeeeee..eekldeaalkklllklekkvkknqelRikyeddpekfmeSEadLdeeikelsvlaeapelYpelvelgavesLvgLlsHeNtD 98 
                 +++++ld+++++ +   ek+d a++++l+l++ek+v+kn+elR+k+e+dp+kfm SEadLd++ik+lsvl+e+pelY+e+++lg+v+sLv+Ll+HeNtD
  EEA18754.1  95 QAMDYLDRQDQDGDtaVEKIDIAWVRRLALNFEKRVSKNAELRAKFENDPQKFMVSEADLDADIKSLSVLSEHPELYEEFAKLGCVASLVSLLAHENTD 193
                 5788999888887778*********************************************************************************** PP

      CTNNBL  99 iaiavv 104
                 iai+++
  EEA18754.1 194 IAIDAI 199
                 ***997 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 1
      CTNNBL  76 YpelvelgavesLvgLls 93 
                  +++v+l+ v+ L++Lls
  EEA18754.1 314 RNKFVSLNGVDVLLQLLS 331
                 5789************97 PP

>> Arm  Armadillo/beta-catenin-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.4   0.0   6.1e-05      0.12       9      40 ..     175     206 ..     167     207 .. 0.90
   2 ?   -1.7   0.0       1.7   3.5e+03       7      23 ..     223     243 ..     220     247 .. 0.76
   3 !    7.6   0.0     0.002       3.9       2      23 ..     311     332 ..     310     356 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 6.1e-05
                 HHTTHHHHHHHHTTTSSHHHHHHHHHHHHHHT CS
         Arm   9 ieaGavppLvrLLssedeevqeeAawALsNLa 40 
                  ++G+v  Lv+LL +e++++  +A  +L+ L+
  EEA18754.1 175 AKLGCVASLVSLLAHENTDIAIDAIQTLTELT 206
                 589*************************9997 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 1.7
                 HHHHTTHHHHHHHHTT....T CS
         Arm   7 avieaGavppLvrLLs....s 23 
                 a+ +a +++ L + Ls    s
  EEA18754.1 223 AMLDADVIELLAQNLSrldeS 243
                 688999999999999866444 PP

  == domain 3  score: 7.6 bits;  conditional E-value: 0.002
                 HHHHHHHHHTTHHHHHHHHTTT CS
         Arm   2 senkdavieaGavppLvrLLss 23 
                 s+n+   +++++v++L++LLss
  EEA18754.1 311 SKNRNKFVSLNGVDVLLQLLSS 332
                 678888899***********94 PP

>> Neurochondrin  Neurochondrin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   1.6e-06    0.0032      99     217 ..     321     445 ..     278     485 .. 0.77
   2 ?   -2.8   0.1      0.74   1.5e+03     371     398 ..     519     546 ..     497     547 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 1.6e-06
  Neurochondrin  99 erIPtllevllkasde......dntemvddayecLkavaatprGakaliasgavsaliqiyse.qsyaldealalllllvsksesssweekelell 187
                    + + +ll++l++  +       d+ e v++ ++cL+ v+  ++G+ +++  ++v+ l+qi++  + +  ++al  l  ++s     ++ ++  e+ 
     EEA18754.1 321 NGVDVLLQLLSSYRKRdpekdsDEEEYVENLFDCLTCVVDEEDGKAKFLEAEGVE-LAQIMLReGKLSKQRALRTLDHALSGQTGAAACDRLIEVA 415
                    556666676665444334677799*****************************96.89999874789999*********99888777778777777 PP

  Neurochondrin 188 aviakiaedfesaedaskfellelLaallp 217
                     +       ++++e++    ll + a ll 
     EEA18754.1 416 GLRTVFGMFMKKQEKEAMEHLLGIFASLLR 445
                    666666666666666666667788887776 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.74
  Neurochondrin 371 fvlAsvrvlgawLaeetsalrkevseLl 398
                    f l  + v+ awL  e+   + ++s Ll
     EEA18754.1 519 FALQTIDVILAWLIAEDDGAKTKISALL 546
                    6677899999***999999999999997 PP

>> MMS19_C  RNAPII transcription regulator C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.8   0.4   2.4e-05     0.048     381     421 ..     185     225 ..     180     227 .. 0.91
   2 !    5.6   0.2    0.0035         7       7      77 ..     237     325 ..     232     377 .. 0.61

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 2.4e-05
     MMS19_C 381 qaLdlpdaevkastLetlksileespslvsehlssLvprLL 421
                   L+ +++++   +++tl+++ +e+ ++ +eh +sLv+ +L
  EEA18754.1 185 SLLAHENTDIAIDAIQTLTELTDEDVQAEQEHWDSLVNAML 225
                 457999*********************************99 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0035
     MMS19_C   7 Lpdsaseasasa..yervLeaLaelssekqlfetlvi......rllnkldlvlksnessaayahailstllkllekkq..........t 77 
                 L   +++++a++  +  vL++L+ l+s++++ e +         ll+++++  ++  ++++y   il  ll+  +k+           +
  EEA18754.1 237 LSRLDESQDADRsgVYYVLNVLENLASQSSIAEKIGQdasiipWLLSRIQQKETPVGQNKQYSAEILAILLQSSSKNRnkfvslngvdV 325
                 44444444444455889999999999999999865333322338999997755555558999999999999988887733333333330 PP

>> Mo25  Mo25-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0      0.38   7.5e+02     160     184 ..     181     205 ..     162     207 .. 0.83
   2 ?   11.9   1.8   5.2e-05       0.1      49     132 ..     206     290 ..     182     388 .. 0.79
   3 ?   -2.0   0.0       0.9   1.8e+03      80     124 ..     425     473 ..     387     481 .. 0.75

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.38
        Mo25 160 wkffeyvensnfeiasdafetlkel 184
                  ++++++  +n++ia da++tl+el
  EEA18754.1 181 ASLVSLLAHENTDIAIDAIQTLTEL 205
                 56788889999**********9986 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 5.2e-05
        Mo25  49 gdpdtepskeqvaqLlqeilkedllyklvknlkklefearkdva..qifsnllrrktksklpaveyletkpeilqlllegyeskei 132
                  d+d ++++e+ + L++++l+ d++++l++nl++l+  +  d      + n+l++  +s++ ++e + +  +i+  ll+ +++ke+
  EEA18754.1 206 TDEDVQAEQEHWDSLVNAMLDADVIELLAQNLSRLDESQDADRSgvYYVLNVLENL-ASQSSIAEKIGQDASIIPWLLSRIQQKET 290
                 335667788999***********************876655554004455556554.56666799999999999999999997543 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 0.9
        Mo25  80 lkklefearkdvaqifsnllrrktksklp....aveyletkpeilqlll 124
                 +kk e ea  ++  if++llr+ ++ + p    +++++e+  e +++l+
  EEA18754.1 425 MKKQEKEAMEHLLGIFASLLRHLPGGSAPrirtLAKFMEKDYEKIEKLI 473
                 6777788888888999999999888888744434444455555555555 PP

>> V-ATPase_H_C  V-ATPase subunit H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.0   0.00057       1.1      70     112 ..     163     205 ..     118     209 .. 0.82
   2 ?   -1.4   0.0       1.2   2.4e+03      45      75 ..     301     331 ..     290     368 .. 0.72
   3 ?   -0.4   0.0      0.61   1.2e+03      34      52 ..     459     477 ..     456     487 .. 0.81
   4 ?   -1.9   0.0       1.8   3.5e+03      82     102 ..     534     554 ..     530     556 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00057
  V-ATPase_H_C  70 lvkllpegkkvleklkaKekimellehedeevkyeALkavqkl 112
                   +++++pe  +  +kl++ + +++ll+he+++++  A++++ +l
    EEA18754.1 163 VLSEHPELYEEFAKLGCVASLVSLLAHENTDIAIDAIQTLTEL 205
                   4556889999999**************************9876 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 1.2
  V-ATPase_H_C  45 kkLiklleeskdktvlavalnDigelvkllp 75 
                   + L+ ll++s+++++  v ln +  l++ll+
    EEA18754.1 301 EILAILLQSSSKNRNKFVSLNGVDVLLQLLS 331
                   4455555666666777777777776666655 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 0.61
  V-ATPase_H_C  34 ekleeknfkllkkLiklle 52 
                   +k+ ek+++ ++kLikl +
    EEA18754.1 459 AKFMEKDYEKIEKLIKLRR 477
                   7999999********9874 PP

  == domain 4  score: -1.9 bits;  conditional E-value: 1.8
  V-ATPase_H_C  82 eklkaKekimellehedeevk 102
                   e+ +aK+ki +ll ++de+++
    EEA18754.1 534 EDDGAKTKISALLGDRDEDIS 554
                   67789************9986 PP

>> Drf_GBD  Diaphanous GTPase-binding Domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   4.2e-05     0.084     101     156 ..     314     370 ..     208     382 .. 0.74
   2 ?   -3.4   0.0       3.1   6.2e+03      28      51 ..     459     482 ..     429     503 .. 0.62

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 4.2e-05
     Drf_GBD 101 vkrFieleGlvaLlnvLskinekkaeeeedlkkey.eiikClKalmNnkvGldavla 156
                  ++F++l+G+ +Ll++Ls + ++  e++ d +  + ++  Cl +++ ++ G ++ l+
  EEA18754.1 314 RNKFVSLNGVDVLLQLLSSYRKRDPEKDSDEEEYVeNLFDCLTCVVDEEDGKAKFLE 370
                 579******************999999666555542466788888888888777776 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 3.1
     Drf_GBD  28 eallalpiekKwqlvvqdkkkkak 51 
                 ++ +++++ek  +l+   ++ ++ 
  EEA18754.1 459 AKFMEKDYEKIEKLIKLRREYSSR 482
                 566778888888888777765555 PP

>> PHTB1_C  PTHB1 C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.8   4.5e-05      0.09     275     343 ..     169     242 ..     160     263 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 4.5e-05
     PHTB1_C 275 klekaanrLssalqLlllllklkqklseeqleiLeavlsplvsdsteqGWeEsvdaa....vshLLrtslsk..s 343
                 +l + +++L ++++L++ll + +++++ + +++L+ +    v+ ++e  W+  v+a+    v +LL + ls+  +
  EEA18754.1 169 ELYEEFAKLGCVASLVSLLAHENTDIAIDAIQTLTELTDEDVQAEQE-HWDSLVNAMldadVIELLAQNLSRldE 242
                 6778999*************************************988.598766555111156788888887432 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.3   0.00026      0.51      30      75 ..     177     228 ..     155     238 .. 0.77
   2 ?   -0.9   0.0       1.1   2.2e+03      23      44 ..     270     289 ..     233     296 .. 0.62

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00026
      HEAT_2  30 pealpaLvellededpavRraaaeaLgaigd......pealpaLkelldddd 75 
                   +++ Lv+ll +e++++   a+++L ++ d      +e +++L  +++d d
  EEA18754.1 177 LGCVASLVSLLAHENTDIAIDAIQTLTELTDedvqaeQEHWDSLVNAMLDAD 228
                 467899***********************75122222557889988888765 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 1.1
      HEAT_2  23 aLgrignpealpaLvelleded 44 
                  +g  ++ +++p+L++ ++ ++
  EEA18754.1 270 KIG--QDASIIPWLLSRIQQKE 289
                 222..23467888887776554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (589 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       726  (0.0404931); expected 358.6 (0.02)
Passed bias filter:                      474  (0.0264376); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.62u 0.33s 00:00:00.95 Elapsed: 00:00:00.46
# Mc/sec: 3844.99
//
Query:       EEA18755.1  [L=501]
Description: DUF1716 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.9e-40  137.2   1.5    7.1e-40  135.4   0.2    2.5  2  CTNNBL         Catenin-beta-like, Arm-motif containing nuclea
      2e-05   24.5   0.1        0.1   12.7   0.0    3.3  3  Arm            Armadillo/beta-catenin-like repeat
     0.0011   18.2   3.8      0.039   13.1   0.4    2.3  2  MMS19_C        RNAPII transcription regulator C-terminal
     0.0022   16.5   0.0     0.0022   16.5   0.0    1.9  3  Neurochondrin  Neurochondrin
  ------ inclusion threshold ------
      0.015   15.4   0.3        0.9    9.7   0.0    3.6  4  V-ATPase_H_C   V-ATPase subunit H
      0.016   14.6   2.2      0.074   12.4   1.6    2.3  2  Mo25           Mo25-like
      0.025   14.1   1.5      0.065   12.8   0.1    2.4  3  Drf_GBD        Diaphanous GTPase-binding Domain
      0.032   13.4   0.8      0.071   12.2   0.8    1.5  1  PHTB1_C        PTHB1 C-terminus
      0.034   14.5   0.9        0.4   11.1   0.3    3.0  2  HEAT_2         HEAT repeats


Domain annotation for each model (and alignments):
>> CTNNBL  Catenin-beta-like, Arm-motif containing nuclear
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  135.4   0.2   3.6e-43   7.1e-40       2     104 .]       7     111 ..       6     111 .. 0.96
   2 ?   -0.8   0.1      0.83   1.7e+03      76      93 ..     226     243 ..     213     245 .. 0.80

  Alignments for each domain:
  == domain 1  score: 135.4 bits;  conditional E-value: 3.6e-43
      CTNNBL   2 eilelldeeeeeee..eekldeaalkklllklekkvkknqelRikyeddpekfmeSEadLdeeikelsvlaeapelYpelvelgavesLvgLlsHeNtD 98 
                 +++++ld+++++ +   ek+d a++++l+l++ek+v+kn+elR+k+e+dp+kfm SEadLd++ik+lsvl+e+pelY+e+++lg+v+sLv+Ll+HeNtD
  EEA18755.1   7 QAMDYLDRQDQDGDtaVEKIDIAWVRRLALNFEKRVSKNAELRAKFENDPQKFMVSEADLDADIKSLSVLSEHPELYEEFAKLGCVASLVSLLAHENTD 105
                 5788999888887778*********************************************************************************** PP

      CTNNBL  99 iaiavv 104
                 iai+++
  EEA18755.1 106 IAIDAI 111
                 ***997 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.83
      CTNNBL  76 YpelvelgavesLvgLls 93 
                  +++v+l+ v+ L++Lls
  EEA18755.1 226 RNKFVSLNGVDVLLQLLS 243
                 5789************97 PP

>> Arm  Armadillo/beta-catenin-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   0.0     5e-05       0.1       9      40 ..      87     118 ..      79     119 .. 0.90
   2 ?   -1.0   0.0         1   2.1e+03       7      23 ..     135     155 ..     132     175 .. 0.74
   3 !    7.9   0.0    0.0016       3.2       2      23 ..     223     244 ..     222     268 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 5e-05
                 HHTTHHHHHHHHTTTSSHHHHHHHHHHHHHHT CS
         Arm   9 ieaGavppLvrLLssedeevqeeAawALsNLa 40 
                  ++G+v  Lv+LL +e++++  +A  +L+ L+
  EEA18755.1  87 AKLGCVASLVSLLAHENTDIAIDAIQTLTELT 118
                 589*************************9997 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 1
                 HHHHTTHHHHHHHHTT....T CS
         Arm   7 avieaGavppLvrLLs....s 23 
                 a+ +a +++ L + Ls    s
  EEA18755.1 135 AMLDADVIELLAQNLSrldeS 155
                 678899999999988877553 PP

  == domain 3  score: 7.9 bits;  conditional E-value: 0.0016
                 HHHHHHHHHTTHHHHHHHHTTT CS
         Arm   2 senkdavieaGavppLvrLLss 23 
                 s+n+   +++++v++L++LLss
  EEA18755.1 223 SKNRNKFVSLNGVDVLLQLLSS 244
                 678888899***********94 PP

>> MMS19_C  RNAPII transcription regulator C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.1   0.4     2e-05     0.039     381     421 ..      97     137 ..      92     139 .. 0.91
   2 !    6.0   0.2    0.0027       5.4       7      77 ..     149     237 ..     144     291 .. 0.61

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2e-05
     MMS19_C 381 qaLdlpdaevkastLetlksileespslvsehlssLvprLL 421
                   L+ +++++   +++tl+++ +e+ ++ +eh +sLv+ +L
  EEA18755.1  97 SLLAHENTDIAIDAIQTLTELTDEDVQAEQEHWDSLVNAML 137
                 457999*********************************99 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.0027
     MMS19_C   7 Lpdsaseasasa..yervLeaLaelssekqlfetlvi......rllnkldlvlksnessaayahailstllkllekkq..........t 77 
                 L   +++++a++  +  vL++L+ l+s++++ e +         ll+++++  ++  ++++y   il  ll+  +k+           +
  EEA18755.1 149 LSRLDESQDADRsgVYYVLNVLENLASQSSIAEKIGQdasiipWLLSRIQQKETPVGQNKQYSAEILAILLQSSSKNRnkfvslngvdV 237
                 44444444444455889999999999999999865333322338999997755555558999999999999988887733333333330 PP

>> Neurochondrin  Neurochondrin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.1       1.1   2.1e+03     144     182 ..      90     126 ..      70     157 .. 0.51
   2 !   16.5   0.0   1.1e-06    0.0022      98     218 ..     232     358 ..     171     399 .. 0.78
   3 ?   -2.5   0.0       0.6   1.2e+03     371     398 ..     431     458 ..     408     459 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 1.1
  Neurochondrin 144 gavsaliqiyseqsyaldealalllllvsksesssweek 182
                    g v  l+    ++   +d+a+ +++ l+   +     e+
     EEA18755.1  90 GCVASLVSLLAHE--NTDIAIDAIQTLTELTDEDVQAEQ 126
                    4444444444333..355555555555544443333333 PP

  == domain 2  score: 16.5 bits;  conditional E-value: 1.1e-06
  Neurochondrin  98 verIPtllevllkasde......dntemvddayecLkavaatprGakaliasgavsaliqiyse.qsyaldealalllllvsksesssweekelel 186
                    ++ + +ll++l++  +       d+ e v++ ++cL+ v+  ++G+ +++  ++v+ l+qi++  + +  ++al  l  ++s     ++ ++  e+
     EEA18755.1 232 LNGVDVLLQLLSSYRKRdpekdsDEEEYVENLFDCLTCVVDEEDGKAKFLEAEGVE-LAQIMLReGKLSKQRALRTLDHALSGQTGAAACDRLIEV 326
                    5566667777766544334677799*****************************96.89999874789999*********9988887777877777 PP

  Neurochondrin 187 laviakiaedfesaedaskfellelLaallps 218
                      +       ++++e++    ll + a ll +
     EEA18755.1 327 AGLRTVFGMFMKKQEKEAMEHLLGIFASLLRH 358
                    76666666666666666666678888887765 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 0.6
  Neurochondrin 371 fvlAsvrvlgawLaeetsalrkevseLl 398
                    f l  + v+ awL  e+   + ++s Ll
     EEA18755.1 431 FALQTIDVILAWLIAEDDGAKTKISALL 458
                    6677899999***999999999999997 PP

>> V-ATPase_H_C  V-ATPase subunit H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.0   0.00045       0.9      70     112 ..      75     117 ..      30     121 .. 0.82
   2 ?   -1.0   0.0      0.94   1.9e+03      45      75 ..     213     243 ..     201     285 .. 0.73
   3 ?    0.0   0.0      0.44   8.8e+02      33      52 ..     370     389 ..     367     400 .. 0.81
   4 ?   -1.6   0.0       1.4   2.8e+03      82     102 ..     446     466 ..     441     468 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00045
  V-ATPase_H_C  70 lvkllpegkkvleklkaKekimellehedeevkyeALkavqkl 112
                   +++++pe  +  +kl++ + +++ll+he+++++  A++++ +l
    EEA18755.1  75 VLSEHPELYEEFAKLGCVASLVSLLAHENTDIAIDAIQTLTEL 117
                   4556889999999**************************9876 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.94
  V-ATPase_H_C  45 kkLiklleeskdktvlavalnDigelvkllp 75 
                   + L+ ll++s+++++  v ln +  l++ll+
    EEA18755.1 213 EILAILLQSSSKNRNKFVSLNGVDVLLQLLS 243
                   4455555666666777777777766666655 PP

  == domain 3  score: 0.0 bits;  conditional E-value: 0.44
  V-ATPase_H_C  33 aekleeknfkllkkLiklle 52 
                   ++k+ ek+++ ++kLikl +
    EEA18755.1 370 LAKFMEKDYEKIEKLIKLRR 389
                   57999999********9874 PP

  == domain 4  score: -1.6 bits;  conditional E-value: 1.4
  V-ATPase_H_C  82 eklkaKekimellehedeevk 102
                   e+ +aK+ki +ll ++de+++
    EEA18755.1 446 EDDGAKTKISALLGDRDEDIS 466
                   67789************9986 PP

>> Mo25  Mo25-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   1.6   3.7e-05     0.074      49     132 ..     118     202 ..     100     300 .. 0.78
   2 ?   -1.5   0.0      0.65   1.3e+03      80     124 ..     337     385 ..     288     394 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 3.7e-05
        Mo25  49 gdpdtepskeqvaqLlqeilkedllyklvknlkklefearkdva..qifsnllrrktksklpaveyletkpeilqlllegyeskei 132
                  d+d ++++e+ + L++++l+ d++++l++nl++l+  +  d      + n+l++  +s++ ++e + +  +i+  ll+ +++ke+
  EEA18755.1 118 TDEDVQAEQEHWDSLVNAMLDADVIELLAQNLSRLDESQDADRSgvYYVLNVLENL-ASQSSIAEKIGQDASIIPWLLSRIQQKET 202
                 335667778899***********************876655554004455556554.56666799999999999999999997543 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.65
        Mo25  80 lkklefearkdvaqifsnllrrktksklp....aveyletkpeilqlll 124
                 +kk e ea  ++  if++llr+ ++ + p    +++++e+  e +++l+
  EEA18755.1 337 MKKQEKEAMEHLLGIFASLLRHLPGGSAPrirtLAKFMEKDYEKIEKLI 385
                 6777788888888999999999888888744444444455555555555 PP

>> Drf_GBD  Diaphanous GTPase-binding Domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       1.4   2.8e+03     160     186 ..      91     117 ..      82     119 .. 0.73
   2 ?   12.8   0.1   3.2e-05     0.065     101     156 ..     226     282 ..     122     295 .. 0.74
   3 ?   -3.1   0.0       2.4   4.8e+03      28      52 ..     371     395 ..     341     416 .. 0.62

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 1.4
     Drf_GBD 160 vikllaqsldserlktrklvlelLtal 186
                 ++ +l++ l+ e+  + +++++ Lt l
  EEA18755.1  91 CVASLVSLLAHENTDIAIDAIQTLTEL 117
                 677788888888888888888877755 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 3.2e-05
     Drf_GBD 101 vkrFieleGlvaLlnvLskinekkaeeeedlkkey.eiikClKalmNnkvGldavla 156
                  ++F++l+G+ +Ll++Ls + ++  e++ d +  + ++  Cl +++ ++ G ++ l+
  EEA18755.1 226 RNKFVSLNGVDVLLQLLSSYRKRDPEKDSDEEEYVeNLFDCLTCVVDEEDGKAKFLE 282
                 579******************999999666555542466788888888888777776 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 2.4
     Drf_GBD  28 eallalpiekKwqlvvqdkkkkakk 52 
                 ++ +++++ek  +l+   ++ ++  
  EEA18755.1 371 AKFMEKDYEKIEKLIKLRREYSSRL 395
                 5667788888888887777665554 PP

>> PHTB1_C  PTHB1 C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.8   3.6e-05     0.071     275     343 ..      81     154 ..      72     175 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 3.6e-05
     PHTB1_C 275 klekaanrLssalqLlllllklkqklseeqleiLeavlsplvsdsteqGWeEsvdaa....vshLLrtslsk..s 343
                 +l + +++L ++++L++ll + +++++ + +++L+ +    v+ ++e  W+  v+a+    v +LL + ls+  +
  EEA18755.1  81 ELYEEFAKLGCVASLVSLLAHENTDIAIDAIQTLTELTDEDVQAEQE-HWDSLVNAMldadVIELLAQNLSRldE 154
                 6778999*************************************988.598766555111156788888887432 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.3    0.0002       0.4      30      75 ..      89     140 ..      63     150 .. 0.77
   2 ?   -0.6   0.0      0.91   1.8e+03      23      44 ..     182     201 ..     145     208 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.0002
      HEAT_2  30 pealpaLvellededpavRraaaeaLgaigd......pealpaLkelldddd 75 
                   +++ Lv+ll +e++++   a+++L ++ d      +e +++L  +++d d
  EEA18755.1  89 LGCVASLVSLLAHENTDIAIDAIQTLTELTDedvqaeQEHWDSLVNAMLDAD 140
                 567899***********************75122222557899988888765 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.91
      HEAT_2  23 aLgrignpealpaLvelleded 44 
                  +g  ++ +++p+L++ ++ ++
  EEA18755.1 182 KIG--QDASIIPWLLSRIQQKE 201
                 222..23467888887776554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (501 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       887  (0.0494729); expected 358.6 (0.02)
Passed bias filter:                      557  (0.031067); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 3368.76
//
Query:       EEA18756.1  [L=1254]
Description: DNA-dependent RNA polymerase II RPB140 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.2e-123  413.1   0.0   1.8e-123  412.5   0.0    1.3  1  RNA_pol_Rpb2_6  RNA polymerase Rpb2, domain 6
    1.8e-57  194.1   0.0    3.5e-57  193.2   0.0    1.4  1  RNA_pol_Rpb2_1  RNA polymerase beta subunit
    1.9e-46  158.1   0.0    3.2e-46  157.4   0.0    1.4  1  RNA_pol_Rpb2_2  RNA polymerase Rpb2, domain 2
    6.9e-33  112.9   0.0    1.5e-32  111.8   0.0    1.6  1  RNA_pol_Rpb2_7  RNA polymerase Rpb2, domain 7
    1.4e-25   89.3   0.5    3.2e-25   88.1   0.1    1.9  2  RNA_pol_Rpb2_3  RNA polymerase Rpb2, domain 3
    1.4e-24   86.2   0.8    4.7e-24   84.5   0.8    2.0  1  RNA_pol_Rpb2_4  RNA polymerase Rpb2, domain 4
    3.1e-21   75.7   0.2    9.6e-21   74.1   0.2    1.9  1  RNA_pol_Rpb2_5  RNA polymerase Rpb2, domain 5


Domain annotation for each model (and alignments):
>> RNA_pol_Rpb2_6  RNA polymerase Rpb2, domain 6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  412.5   0.0  7.1e-127  1.8e-123       1     390 []     779    1152 ..     779    1152 .. 0.95

  Alignments for each domain:
  == domain 1  score: 412.5 bits;  conditional E-value: 7.1e-127
                      HHHT-SS-TTB-HHHHHHHHHHGGGB-S---TTTTT---SSEEEESS----SSB-S.TTTTTS........GGGS-SEEEEEBBBS--TTTTT CS
  RNA_pol_Rpb2_6    1 vaklapvvehvqspriiiqaamekqalgiyslnkfkrsnqktyllcinqkPlvktgdkveagqvldgpatekgelalGqnavVAvmsyeGYni 93  
                      +a+++p+++h+qspr+++q+am+kqa+g+  +n  +r+++  ++l+++qkPl +t+ ++e+++        + el++Gqna+VA+++y+GYn+
      EEA18756.1  779 CASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNFDQRMETMANILYYPQKPLATTR-SMEFLK--------FRELPAGQNAIVAIACYSGYNQ 862 
                      6999****************************************************.******........********************** PP

                      TT-EEEBCHHHHTTTT-EEEEEE..EEE--SSSS-.--.-S--..-....-SS-GGGS-TTSB--SS-EEETT-EEE---..B-----...-- CS
  RNA_pol_Rpb2_6   94 EDaiilnerlvdrdvftsihikeyeveardtklge.eeitrdipnv....seealkkLdedGivrvgaevkegdilvgkvtkgeteltpeekl 181 
                      ED++i+n++++dr++f+s+++++y+   r+  l++ e++ + + ++    ++  ++k+++dG+v +g +v+ +di++gk+      l pe+++
      EEA18756.1  863 EDSVIMNQSSIDRGLFRSLFYRTYTEAERKLGLQTiEKFEKPMRSDtlgmRKGTYDKIEDDGLVAPGVRVTGEDIIIGKT----APLAPESEE 951 
                      ***********************88888888888866655555555999999***************************8....668888888 PP

                      ---------..-B---EE--TT-EEEEEEEEE.......EE-TT--EEEEEEEEEEE---TT-BEEETTS---BBEEEB-TTTSEEETTS--- CS
  RNA_pol_Rpb2_6  182 lraifgekarevkdtslrvksgeegvVdkvkvfsrekgdelkagvnklvkvyvaqkRklqvGDKfasrhGqKGvvslilpqeDmPfledGivv 274 
                      l + +  ka+++ d s+ ++ +e+g+Vd+v +      ++ ++   +lvkv++++++ +q+GDKfasrhGqKG++++++++eDmPf+++Giv+
      EEA18756.1  952 LGQRT--KAHTKVDVSTPLRATESGIVDQVLL------TTGNDPDLRLVKVRMRTTKIPQIGDKFASRHGQKGTIGITYRHEDMPFTREGIVP 1036
                      86655..55557999999999***********......5777889************************************************ PP

                      SEEE-GGGCHHH-BTTHHHHHHHHHCCCSSSS--B--TT-...-HHHHHHHHHTTS-TT-EE-EEETTTS-B-SS-EEB-EEEEEEBS--CCC CS
  RNA_pol_Rpb2_6  275 DivlNPlgvPSRmtigqllEtllgkaaalegkkvdatvFdgakeeeikelLeeagleasGkevlydGrtGekleaeifvGviYylkLkhlved 367 
                      D+++NP+++PSRmti++l+E+ l+k+++l+g++ dat+F+  + + +++lL+e+g++++G ev+y+G tG+kl+a++f+G++Yy++L+h+v+d
      EEA18756.1 1037 DLIINPHAIPSRMTIAHLIECQLSKVSSLRGFEGDATPFTDVTVDSVSRLLREHGYQSRGFEVMYNGHTGKKLKAQVFLGPTYYQRLRHMVDD 1129
                      ****************************************9999************************************************* PP

                      S----SS--B-TTT--B-SCGGG CS
  RNA_pol_Rpb2_6  368 KihaRstGpyslltqQPlgGkaq 390 
                      KihaR++Gp++ lt+QP++G+a+
      EEA18756.1 1130 KIHARARGPTQILTRQPVEGRAR 1152
                      *********************96 PP

>> RNA_pol_Rpb2_1  RNA polymerase beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  193.2   0.0   1.3e-60   3.5e-57       1     196 [.      37     466 ..      37     472 .. 0.98

  Alignments for each domain:
  == domain 1  score: 193.2 bits;  conditional E-value: 1.3e-60
                     CTTHHHHHHHHHHHHTHHHHHCTTSSECCHCSSSHCSSSC........EEEEEEEEEEESCSSECTTSCEEES.HHHHHHCTSBXEEEEEEEEEE CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  RNA_pol_Rpb2_1   1 gLvsqqldSFnkfveqdlekiikeeaaieseeeiqssgee........lelkfvsirlgkPvvdesdasereiyPkearlrnltYsaplyvklkl 87 
                     gLvsqqldSF++f+  ++++ ++e+ ++++++ i+ +++e        +e+k++ i l++P+++e++++ + ++P+ear rnltY +ply++++ 
      EEA18756.1  37 GLVSQQLDSFDEFISSTMQELVEEQGQVTIDQTITPNEDEidpvvirrYEIKYGTIMLARPSFSEINGAATLLLPMEARHRNLTYASPLYLNVQR 131
                     69********************************9777779*****************************************************9 PP

                     EECCCC...............................TCCEEEEEEEEEEEEEXBTTSTTSSSTTS.HHHHHHTTS.TTS..SSEEETTCEEEEX CS
                     xxxxxx...............................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  RNA_pol_Rpb2_1  88 vvyekd...............................nkeeikeeevyiGelPlMlrskacvlseaseeelvelkEcpldqGGyFiinGtekviv 151
                     + +e                                  ++e++ +  yiG++P+Ml+sk+c l ++se+ l++ +Ecp+d GGyFiinG+ekv++
      EEA18756.1 132 RLTEGRerkavdregegdeneeqkpggtyldweekplVVSEEEAKGCYIGRIPIMLKSKYCLLRDLSEQSLYNWNECPYDSGGYFIINGSEKVLI 226
                     998766899***************************99999999*************************************************** PP

                     EEEE........................................................................................... CS
                     xxxx........................................................................................... RF
  RNA_pol_Rpb2_1 152 aqek........................................................................................... 155
                     aqe+                                                                                           
      EEA18756.1 227 AQERsagnivqvfkkappsptpyiaeirsavekgsrilsqlslklfakgdsskggfgptirsslpyiktdipivivfralgvvsdedilnhicyd 321
                     *********************************************************************************************** PP

                     ............................................................................................... CS
                     ............................................................................................... RF
  RNA_pol_Rpb2_1 156 ............................................................................................... 155
                                                                                                                    
      EEA18756.1 322 rndtpmlemlkpcieegfviqdrevaldfiskrgssqtsmshdrrvryareimqkeflphisqsegsetrkafflgymvhkllqcalgrrdvddr 416
                     *********************************************************************************************** PP

                     .........XHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTSSSSSHHHHS CS
                     .........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  RNA_pol_Rpb2_1 156 .........laGeLlaslfrvllkklerdvkerlqksleklddlmlqllv 196
                              laG+Lla lfr+l+ +++rd+ +++q+++e+++++ l++ +
      EEA18756.1 417 dhfgkkrldLAGPLLATLFRTLFTRVTRDLTRYVQRCVETNREVVLNVGL 466
                     ******************************************99887655 PP

>> RNA_pol_Rpb2_2  RNA polymerase Rpb2, domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  157.4   0.0   1.3e-49   3.2e-46      39     190 .]     284     425 ..     232     425 .. 0.85

  Alignments for each domain:
  == domain 1  score: 157.4 bits;  conditional E-value: 1.3e-49
                     CEEEEECTTSSSEEEHHHHHHHTT--STTHHHHHHTSSSTTHHHHHHHHHHHHHHCTSSSCHHHHHHHHHCSSTTSSSCCCCCHHHHHHHCHHHH CS
  RNA_pol_Rpb2_2  39 ktliwtriskkrkipivivlkAlglvsdreIlericydsedsqlleelleeleekeeiqtqeealdyigkvvalrrgeearlqsareilqkrydl 133
                      t++ +++++k++ipiviv++Alg+vsd++Il++icyd +d+ +le+l+++ ee ++iq++e+ald+i k    r ++++ + ++r++   ry++
      EEA18756.1 284 PTIRSSLPYIKTDIPIVIVFRALGVVSDEDILNHICYDRNDTPMLEMLKPCIEEGFVIQDREVALDFISK----RGSSQTSMSHDRRV---RYAR 371
                     4678999**************************************************************9....88888888888888...9*** PP

                     HHHTTTTSSTTTTTSSSTCHH..HHHHHHHHHHHHHHHHTTSSSS--TTSGGGEEEE CS
  RNA_pol_Rpb2_2 134 geigreklnkhlglseslenkrlkaqdilymidrLlslklgrrevDDiDhlgnkRvr 190
                     ++ ++e l+ h+ +se  e++  ka++++ym+++Ll+++lgrr+vDD+Dh+g+kR++
      EEA18756.1 372 EIMQKEFLP-HISQSEGSETR--KAFFLGYMVHKLLQCALGRRDVDDRDHFGKKRLD 425
                     *********.*******9999..********************************96 PP

>> RNA_pol_Rpb2_7  RNA polymerase Rpb2, domain 7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.8   0.0   5.9e-36   1.5e-32       1      86 [.    1154    1246 ..    1154    1247 .. 0.97

  Alignments for each domain:
  == domain 1  score: 111.8 bits;  conditional E-value: 5.9e-36
                      BBEEEEHHHHHHHHHHTBHHHHHHHHTTTTTEEEEEEESSSSSCCCEE.......EBTTTTCSSSEEEEEEEHHHHHHHHHHHHTTBEEEEES CS
  RNA_pol_Rpb2_7    1 GGlrfGEMErdaliayGaaalLkerltikSDavevdvcgrckllaaan.......eCkivkseekiekveipeafklLlqeLqslgialklll 86  
                      GGlrfGEMErd++ia+Ga+a+Lkerl++ SD ++v++c++c+l++ ++       eC++++++++i++v+ip+a+klL+qeL +++ia ++++
      EEA18756.1 1154 GGLRFGEMERDCMIAHGASAFLKERLFDVSDPFRVHICDDCGLMTPIAklkkglfECRLCNNKHRISQVHIPYAAKLLFQELAAMNIAARMFT 1246
                      9*******************************************9988899*************************************99976 PP

>> RNA_pol_Rpb2_3  RNA polymerase Rpb2, domain 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0         4     1e+04      10      21 ..     359     370 ..     353     377 .. 0.73
   2 !   88.1   0.1   1.2e-28   3.2e-25       1      68 []     499     563 ..     499     563 .. 0.99

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 4
  RNA_pol_Rpb2_3  10 selshlrrvssl 21 
                     +++sh rrv+  
      EEA18756.1 359 TSMSHDRRVRYA 370
                     579999999855 PP

  == domain 2  score: 88.1 bits;  conditional E-value: 1.2e-28
  RNA_pol_Rpb2_3   1 qvldrlnplselshlrrvsslrgglskerkttevRdlhpshwGriCpveTPEGencGlvksLallarv 68 
                     qvl r+++ s+lshlrr +++   + ++ k +++R+lh++hwG +Cp+eTPEG+ cGlvk+Lal++++
      EEA18756.1 499 QVLSRYTFASTLSHLRRTNTP---IGRDGKIAKPRQLHNTHWGLVCPAETPEGQACGLVKNLALMCSI 563
                     89*******************...******************************************97 PP

>> RNA_pol_Rpb2_4  RNA polymerase Rpb2, domain 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.5   0.8   1.8e-27   4.7e-24       1      61 [.     598     658 ..     598     659 .. 0.99

  Alignments for each domain:
  == domain 1  score: 84.5 bits;  conditional E-value: 1.8e-27
                     EECTT-BEEE-S-HCCHHHHHHHHCCTTSS-TT-EEEE-TTT--EEEE-SSEEB-EEEEE- CS
  RNA_pol_Rpb2_4   1 VfvNGrllGvtrdpkklvetlRelRRkgkiseevsivlnekqkevkiatDgGRvcRPliiV 61 
                     VfvNG+++Gv+rdp++lv+t+++lRR++ is+evs v++++++e ki+tD+GRvcRPl+++
      EEA18756.1 598 VFVNGVWVGVHRDPAHLVSTVQSLRRRNMISHEVSLVRDIRDREFKIFTDAGRVCRPLFVI 658
                     9***********************************************************8 PP

>> RNA_pol_Rpb2_5  RNA polymerase Rpb2, domain 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.1   0.2   3.7e-24   9.6e-21       1      58 []     702     772 ..     702     772 .. 0.92

  Alignments for each domain:
  == domain 1  score: 74.1 bits;  conditional E-value: 3.7e-24
                     HHHHHHTTSEEEEEHHHHTT--EESSTTTCSST-SSTTTSS-.............-TTSSSST-SEEES-G CS
  RNA_pol_Rpb2_5   1 wddLlregvvEylDaeEEetamIamtpedleksreekealee.............kenskshtyTHcEIhP 58 
                     w++L+++gv+Ey+DaeEEet+mIam+pedle s++ +++++                ++++h +THcEIhP
      EEA18756.1 702 WEGLVKSGVIEYVDAEEEETIMIAMSPEDLEISKQLQAGYTLpednndpnkrvrsVLSQRAHIWTHCEIHP 772
                     *********************************77776666689********99977788889*******9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1254 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       455  (0.0253779); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.83u 0.31s 00:00:01.13 Elapsed: 00:00:00.48
# Mc/sec: 7803.68
//
Query:       EEA18757.1  [L=264]
Description: GTP-binding protein EsdC [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    6.8e-05   23.0   0.0    0.00011   22.3   0.0    1.3  1  AMPK1_CBM  Glycogen recognition site of AMP-activated protein
  ------ inclusion threshold ------
        2.4    8.0   8.3        3.1    7.6   8.3    1.1  1  SPX        SPX domain


Domain annotation for each model (and alignments):
>> AMPK1_CBM  Glycogen recognition site of AMP-activated protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.3   0.0   1.2e-08   0.00011       8      79 ..      13      95 ..       6      99 .. 0.80

  Alignments for each domain:
  == domain 1  score: 22.3 bits;  conditional E-value: 1.2e-08
   AMPK1_CBM  8 kggGkkVyvtGsfnnWkkkipLk.........ksekdfsvilkLpeGthqykFiVDg.ewrvdpdlptat.deeGnlnNviev 79
                +++ k+V + Gs++n+++++pL+         + + +f++ +    G++ y +i Dg ++ +dp  +++t  ++G   N+++v
  EEA18757.1 13 SRSVKSVHLVGSWDNYSRELPLSkdttksgawTGKFRFQTSVLQLGGRYWYYYIMDGyHVSHDPAVEFTTePTTGRKLNILDV 95
                556789*****************998866654444566776666789**********55789**99998835789*****999 PP

>> SPX  SPX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   8.3   0.00035       3.1      60     156 ..     101     250 ..      71     260 .. 0.62

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.00035
         SPX  60 sse....rtepstsaaadesgnsaadasssepkdeae...............................slprrsplsrssrssssygglvssppsanss 123
                 ss+    ++++ +++ + ++g               +                               +l++r + sr s+++ sy+++++s+  ++ s
  EEA18757.1 101 SSKsssrSSHARRESVDIPKG---------------RalspskiqhpkpskpyasrgiregdcfptvdELSDRFSDSRLSDDYDSYSSSPPSSVGSSLS 184
                 222222212222222222222...............133333333444445577788899999998888888888888888888888888888888888 PP

         SPX 124 sssddssesnpa.................................dssssssssesesssssspsl 156
                 s +d+ s+s+ +                                  s+ss+ s+ ses+s+s+  +
  EEA18757.1 185 SRTDSTSPSSLSslsdpasvcrcerygitrkgdrvkldcggsrcgYSDSSDGSECSESESDSEYRS 250
                 877777777765899999999999999999999999999999888555555554444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (264 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       531  (0.0296168); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.22s 00:00:00.67 Elapsed: 00:00:00.40
# Mc/sec: 1971.75
//
Query:       EEA18758.1  [L=552]
Description: D-aminopeptidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.6e-47  159.8   0.0    1.4e-46  159.3   0.0    1.1  1  Beta-lactamase  Beta-lactamase
    2.6e-12   47.1   0.0    4.6e-12   46.3   0.0    1.4  1  DUF3471         Domain of unknown function (DUF3471)


Domain annotation for each model (and alignments):
>> Beta-lactamase  Beta-lactamase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  159.3   0.0   1.5e-50   1.4e-46       2     314 ..      10     344 ..       9     356 .. 0.83

  Alignments for each domain:
  == domain 1  score: 159.3 bits;  conditional E-value: 1.5e-50
                     HHHHHHHHHHTTESEEEEEEEETTEEEEEEEEEEEETTTTEEESTTSBEEEGGGHHHHHHHHHHHHHHTTS...SCTTSBGGGTST.....TCTT CS
  Beta-lactamase   2 drlvrelmaqggipGvavavvrdgkvvldkggGvadleggrpvtadtlfriaSvtKtftaaavlqlveeGk...ldLddpVskylP.....efag 88 
                     ++lv++lm q +ipG+++av+++ ++   kg+G a+ e++ p+t dtlf+iaS+ K++taa v+ lve++    +++ +  s+ lP     + ++
      EEA18758.1  10 TSLVTDLMRQNKIPGLSIAVIHHEEIA-SKGYGIASYETNMPCTGDTLFDIASCAKSLTAASVALLVEDKDypeVQYEALMSHLLPddfvmAEKS 103
                     578999********************7.7777**************************************5555****************66666 PP

                     GGGTTEBHHHHHTTHSSCSSSSTSTTCTSHHHTH......HHHHHHHHHSBSSSSTTSCEE-SHHHHHHHHHHHHHHHTSHHHHHHHHHTTTTTT CS
  Beta-lactamase  89 pgkgkiTlrdLltHtsGlpdlfasdlleeaaada......aellralatlppkyapGtkwgYsntgygllgellekvtgrsleqllreeilrpLg 177
                     + +g +T++d ++H+ G++ + +  +     ++a      ++++r l++l+p+ + ++++ Y+n  y+++ +l+e+ +++s+ ++l+e+i++pL+
      EEA18758.1 104 YTDG-VTVEDIISHRTGMACYVFLHDNAFMGPNAthpdnaKSITRNLRNLKPAAPLRSRYLYCNQMYTVATHLVEHKSKKSFSRFLDERIFAPLN 197
                     6666.*************99877777777776778************************************************************ PP

                     STTEESSTTGGGGGGBEEEEEEETCEEECSCETTHHHHC........TTTBEEEEHHHHHHHH......HHHHHCCSSSSHHHHHHHHHHHTSEE CS
  Beta-lactamase 178 mkdtelgppesgdprdaagytgngpearappanlpaeae........gagglistardlarfl......glalegglllsaetlaqltaklssgt 258
                     m +t+l p ++ ++      ++   ++ ++ + +    +        gag +is+a+d  +++      ++ ++++ + ++ t ++ + +  +++
      EEA18758.1 198 MASTTLQPTSAHAKGWSDRMAKGYIWQNDAWRGF----DpqdcpegqGAGSVISSANDFIKWVkallyrEGPINDR-VYQGLTKMRSIVNPNARR 287
                     ********99986665555533333333333333....134668889****************8766652222222.233333333467788888 PP

                     EECTTEEEECECSSEEEEECCHTEEEEEEE..STEEEEEEEECGGTEEEEEEESBCSS CS
  Beta-lactamase 259 trpagiraglglGwvladktgapgtfghtG..ggygtyvfvdpeanlvvavltnrdpp 314
                      +p +++a +  G  ++ ++g  +++gh+G  +g+++ +++ p+ + +++vl n+ + 
      EEA18758.1 288 LKPHTTPAIYTAGMEMYYYRG-NMIIGHDGtiPGFRSRFIFMPDLKFGAVVLGNSAGA 344
                     888888888899999999999.5*******************************9984 PP

>> DUF3471  Domain of unknown function (DUF3471)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.3   0.0   5.1e-16   4.6e-12       5     102 ..     443     543 ..     439     544 .. 0.81

  Alignments for each domain:
  == domain 1  score: 46.3 bits;  conditional E-value: 5.1e-16
     DUF3471   5 nttpslpleaYvGtYedpgygtvtvslegd.rLflrfdrtprlqge...Lehyhgdf.Flarwddrs..seadakveFeldedgkvtrltlkaefsfdf 96 
                 ++++  pleaYvG+++++gy  + v+ ++d +L++++++ +   g    +eh++ ++ ++a+++d    +++++ + F + e+gkv +++l++e+++  
  EEA18758.1 443 PPPQRTPLEAYVGRFWNAGYRAMIVTIKDDdQLYIDATDRS--NGFtmtFEHVKNQTeYIAHVRDVIelEDESVDARFVF-ENGKVVKIGLDLEPAI-- 536
                 678899********************998879**9995555..544569**************99879977777777765.89*********55544.. PP

     DUF3471  97 kd.lnfe 102
                 ++ ++fe
  EEA18758.1 537 REmIWFE 543
                 5557776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (552 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       731  (0.0407719); expected 358.6 (0.02)
Passed bias filter:                      483  (0.0269396); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.43
# Mc/sec: 3820.25
//
Query:       EEA18759.1  [L=1161]
Description: nuclear pore complex subunit Nup85, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.8e-25   88.5   0.0    2.9e-18   65.8   0.0    2.3  2  Nucleopor_Nup85  Nup85 Nucleoporin
  ------ inclusion threshold ------
       0.17   12.6  15.0        9.4    7.0   0.0    2.8  2  FYDLN_acid       Protein of unknown function (FYDLN_acid)
       0.25    9.5  14.3       0.37    8.9  14.3    1.2  1  Nop14            Nop14-like family
        1.1    8.7  15.3        1.7    8.0  15.3    1.2  1  SDA1             SDA1
        6.9    4.8  10.3         10    4.2  10.3    1.1  1  CDC45            CDC45-like protein


Domain annotation for each model (and alignments):
>> Nucleopor_Nup85  Nup85 Nucleoporin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.0   4.5e-08   0.00016     108     173 ..     394     454 ..     324     522 .. 0.87
   2 !   65.8   0.0     8e-22   2.9e-18     239     509 ..     573     941 ..     560     961 .. 0.81

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 4.5e-08
                      HHHHHHHHHHHHTTS--..SHHHHHTTCCSS-CSSSSSGSHHHHHHHHHHHHTT-HHHHHHHHTTT CS
  Nucleopor_Nup85 108 stllesLleWvnrsdgefppseelieevleskeeeeveehpdfWklvnqlllrGlfdqavalLels 173
                      + +++ L++W+n    +   s  ++e++ +   + +++ +p fW+++   +lrG+f++  alL++ 
       EEA18759.1 394 TPIPKILVDWLNA--NH-LGSLHEMESLQQ--ASPNPTASPHFWEIIQAGVLRGRFSEIAALLRSA 454
                      568889*******..44.466777777665..5799**************************9954 PP

  == domain 2  score: 65.8 bits;  conditional E-value: 8e-22
                      S-HHHHHHHHHHHHHHHT-HHHHHHT-SSHHHHHHHHHHHT--................-T.HH.HHHHHHHHHS............---TTST CS
  Nucleopor_Nup85 239 isgelrdnledllkilsGneskileysetWyellvglllYyiP................tl.kkleylqlsakkcl...........pedetne 304
                      i   + +++++++ +++G+ s i++  ++W+e+ +gl  + +                  +  + + +   +++c+           +++   +
       EEA18759.1 573 IPWSIYQGISNIYGVILGKPSVIMSVAQDWIEATIGLTAWWDGqelgnngvfgnreqatDVeRQ-DAYLRRLNDCFgevidgsemqsRPNPLVR 665
                      555678899**********************************999999999999876522222.43444445555888888888887778889 PP

                      THHHHHHHHTS--GGGHHHHHHH..HHHHHHHHHHHHHHTTSS--.---....................S---SSSTTHHHHHHHHHHHT.... CS
  Nucleopor_Nup85 305 leqlclailegdilsvlkelesllddswfaahladLleakgllee.ass....................eledlflreyllleyasells.... 373
                      l+ ++  ++eg++   +k l+ +  ++++aa +a++ ++ g le  +++                       d ++++  l  ya  l      
       EEA18759.1 666 LDVAVTCVFEGNVSGTIKLLQTW--SLCIAAAVAEIAHEGGWLEMsTANmpgflnrddlmvlsygqnddAALDQISKDEVLDVYAEKLGDrdqf 757
                      ***********************..******************6543335777777777777787666655566667799********988888 PP

                      .....-TTTHHHHHHHHHS-S..HHHHHHHHHHGGG----SHHHHHHHHHHHHHHT-HHHHHHHHHHHHHHHHHHH......HHHHHHHHHHXX CS
  Nucleopor_Nup85 374 .....hkslWqvaigylslcp..segraaleelLprvpletnddiekllsiCaklkLpevaksickilgqrllkeg......rlgeAltwfska 454
                            ++ W++a+++ls ++  +  r+++++lL ++p+ t +++++++++C +l+++++ ++i    g + ++ g       +g A+ +f++a
       EEA18759.1 758 eyngtVRKGWELALEVLSRMEdnKTTRERVSALLNKIPVGTVQQVDRVITLCIDLGFEDEGRKIAANFGEKIIAAGqaradcDYGLAMICFARA 851
                      888888999************99999**********************************************999966666679********** PP

                      XXXXXHHHHHHHHHHHHHHHHHXX....XXXXHHHH...................HHHHHHHHH....HHHHHHXXX..............X CS
  Nucleopor_Nup85 455 gdielvkriawqlfeasllegeplsedlddnlgsai...................llsqrLsfl....akyreFykl..............y 509
                      +++  vk+ia+ l+ a++l+++  +    +nlg ++                     +q + f+    a++r+Fy l              +
       EEA18759.1 852 RSVRKVKEIANSLI-AYSLQQSRAW-PPAENLGGQLrslvqnpkvclssiaavdsEAAQIIQFYasgyATLRRFYDLrdepvlskgskphlR 941
                      **************.6666666665.44677777777888***************9999999962222689*****9555555555555554 PP

>> FYDLN_acid  Protein of unknown function (FYDLN_acid)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7  14.6     0.056     2e+02      32      99 ..     108     180 ..     103     192 .. 0.33
   2 ?    7.0   0.0    0.0026       9.4      15      39 ..     919     943 ..     917     963 .. 0.71

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.056
  FYDLN_acid  32 cgeefepeev.....lksraaaaeaeeakkkkeeeedeedeeeeedvsd.edadeeeee..dddddvdleeddddd 99 
                 cg+  ++ +       +  +a+++ e++ ++ eeeed+e e+ +e  ++ e++ e+ee   ++  d+d ee +dd+
  EEA18759.1 108 CGNNLKVRNRkphglSQMTTASEDWEDE-EDVEEEEDAEPEDGNEYSDEvEEDYEDEEGegEE--DQDEEEYEDDE 180
                 5555555554333221111122222222.2222222222222222222212222222222222..23333333333 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0026
  FYDLN_acid  15 cgakFYDLnkdPivcpkcgeefepe 39 
                 + ++FYDL+ +P+ +  ++    p 
  EEA18759.1 919 TLRRFYDLRDEPVLSKGSKPHLRPL 943
                 568**********997666555544 PP

>> Nop14  Nop14-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9  14.3    0.0001      0.37     335     410 ..     121     194 ..     106     275 .. 0.48

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0001
       Nop14 335 glgkglkataeeeeeededdfeedddlveseseeee..eeeeedeeeeedeeeeeeeeededdlsdleseeeeeedel 410
                 gl++ ++  a+e+ e++ed +ee+d + e+++e ++  ee+ edee e +e+++e  ee edd+++  + e +  +++
  EEA18759.1 121 GLSQMTT--ASEDWEDEEDVEEEEDAEPEDGNEYSDevEEDYEDEEGEGEEDQDE--EEYEDDENSVGDVEMDATSDF 194
                 4444443..3333222222222222222333332221233333333333333333..333333333333344444444 PP

>> SDA1  SDA1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0  15.3   0.00049       1.7     100     181 ..     128     222 ..     110     283 .. 0.47

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00049
        SDA1 100 deedwevesdddseedseggwidvesdeeeieesdesedeeeeeeeeeekeekeeeeeeeeeeeeeeeeeeeeeekekkkk.................. 180
                  +edwe e+d ++eed e +  +  sd  e+e +d  edee e ee++++ee e++e++       + e ++ ++     +                  
  EEA18759.1 128 ASEDWEDEEDVEEEEDAEPEDGNEYSD--EVE-ED-YEDEEGEGEEDQDEEEYEDDENSV-----GDVEMDATSD-----Faamqtgfsnsifkgfgqs 212
                 445555555444444443331111111..122.12.222222222222222222222221.....1111111111.....1222334555566766666 PP

        SDA1 181 .........k 181
                          +
  EEA18759.1 213 sapaqkriyS 222
                 5555554441 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2  10.3    0.0029        10     120     172 ..     129     188 ..     112     261 .. 0.47

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.0029
       CDC45 120 reayealeeeeesdeede........eeeeeddddeeeeeeeeedeedeeedeeeskkkrk 172
                  e++e  e+ ee++ + e        +e eed +dee e ee++dee++e+de++ +  ++
  EEA18759.1 129 SEDWEDEEDVEEEE-DAEpedgneysDEVEEDYEDEEGEGEEDQDEEEYEDDENSVGDVEM 188
                 33333333333332.1111222222222222222222222222223333333322222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1161 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       844  (0.0470746); expected 358.6 (0.02)
Passed bias filter:                      522  (0.0291148); expected 358.6 (0.02)
Passed Vit filter:                        75  (0.00418317); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.98u 0.32s 00:00:01.30 Elapsed: 00:00:00.48
# Mc/sec: 7284.24
//
Query:       EEA18760.1  [L=285]
Description: hypothetical protein PMAA_010410 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.8e-15   57.1   0.0    2.3e-15   56.7   0.0    1.1  1  DNA_pol_A_exo1  3'-5' exonuclease


Domain annotation for each model (and alignments):
>> DNA_pol_A_exo1  3'-5' exonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.7   0.0   1.3e-19   2.3e-15       2     169 ..       5     203 ..       4     210 .. 0.88

  Alignments for each domain:
  == domain 1  score: 56.7 bits;  conditional E-value: 1.3e-19
                     EEEHSHHHHHHHHHHHTTSS......EEEEEEEEE-SSSTTSSEEEEEEEEECS..SEEEEEECTTTTTT-......HGHHHHHHHT-TTSEEEE CS
  DNA_pol_A_exo1   2 eivtdeeeleelieelknlk......vvavDtEttsldlisatlvliliqlgek..eeayiidplelgddv......alealkrlledenitkvg 82 
                     ++v+++++l+e++  ++n+k       + +D E  +l     ++ + +i+++ +  +++y+id + l ++        ++ lk++le ++i+kv+
      EEA18760.1   5 TVVDTDSALQEFLTGIENCKvkdvppSLYFDLEGVRLGR---NGTISIISVFIQplNQVYLIDVFTLSEKAflitndKQTSLKTILEAPSIPKVF 96 
                     5799***********************************...66666666666666*********9999888**9999***************** PP

                     SSHHHHHHHHHHHHTS--SSEEEHHHHHHHTTHSTT...SSHHHHHHHHHS..B---GHCCTTSSTTT.................SSS-HHHHHH CS
  DNA_pol_A_exo1  83 hnakfDlevlardfgielenlfdtmlaayvldyers...hsLdsLaekylg..dleldkeeqiakwqk.................arplleeqll 155
                     ++ ++D +++  ++gi l+ + d+++++    + ++    +L++ +e+  +   +el+k +qi+   +                 +rp + + ++
      EEA18760.1  97 FDVRNDSDAMCSHHGIRLQCVKDLQVMELAVRFGSQkyvAGLAKCIENHANlpPIELQKWKQIKA--SvgqlwdprrggsyqvfnQRPIRTDIIQ 189
                     ***********************************99**************66555555555543..34468999******************** PP

                     HHHHHHHTHHHHHH CS
  DNA_pol_A_exo1 156 YAaeDadvllrlfk 169
                     Y+a+D+ +l  l++
      EEA18760.1 190 YCAQDVTILPSLWN 203
                     ********988876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (285 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       366  (0.0204139); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 2073.32
//
Query:       EEA18761.1  [L=498]
Description: indoleamine 2,3-dioxygenase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-37  129.4   0.0      2e-37  129.0   0.0    1.1  1  IDO       Indoleamine 2,3-dioxygenase


Domain annotation for each model (and alignments):
>> IDO  Indoleamine 2,3-dioxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  129.0   0.0   1.1e-41     2e-37       4     377 ..      31     411 ..      28     446 .. 0.84

  Alignments for each domain:
  == domain 1  score: 129.0 bits;  conditional E-value: 1.1e-41
                 SST-BTTTBTS.-SS--SS--G.GGHHHHHHHHTH........HHHHHTTHHHHHHHTS----S..TT--SHHHHHHHHHHHHHHHH..HHHHTT.SS- CS
         IDO   4 dfdvsektGFlpeeaPlerLpdeyyepWeellenl........relieserlRekvrklpvlst..deLkseeelrrAhlvLaflah..aYvwse.gkk 89 
                  f +++ +GF+p +   ++Lp   ++p  +lle++        + l+++  l ++v+  p l+   d++ + +  +r   +L+ +    +Yv s+    
  EEA18761.1  31 PFTITTASGFMPYQVAPTQLPP-IFKPLTDLLERMpvltlngkPGLLATYDLGKAVEGFPDLTDeiDKVLT-KDGKRDLFMLTAIFRdySYVASAyI-- 125
                 699******************8.7*******************999**************99752133333.3677888888877661245555431.. PP

                 --S...................EE-HHHHHHHHHHHHHHTS-SS--HHH.HTTSSEEESSTTS-.SSG...GGEEES--SSTT....SSHHHHHHHHHH CS
         IDO  90 pse...................vlPasiavPllevsekLelpPvltYad.lvLwNfkkldeeeelsklleldnlrilttftgt....edeewFylvsva 164
                   e                   vlP++ia P+++ +e L+lpP l+Ya+   L N++  ++    s+  e dnlr+++ f +      +e  F+l+ v 
  EEA18761.1 126 -LEpcwenwckdpdsgyglgreVLPHNIAGPMWRCAEILDLPPFLSYAAsYALFNYTLENP----SRGYEYDNLRLIRGFEHGlnpkSSEAGFILTHVD 219
                 .22445678889999********************************87368****55544....46889******99998753333799********* PP

                 HHHHHHHHHTTHHHHHHHHHT.T-HHHHHHHHHHHHHHHHHHHHHHTTHHHHS-HHHHHHTHHHHH--SSSBGG..GTT-BEETTTE...SSEB-B--- CS
         IDO 165 iEargaealklmlsaldeare.adearvtsaLerlaevideltklLervrekcdpevFYhkiRpflaGskndaeaglpegvlyegveegkeevrqlsGg 262
                 +  + a++++  +++ld +++ ++++ v++ ++++ ++++ +++ +e++ ++ +p+  Y ++R f+ G ++++    p+gv+yeg++   ++++ ++G 
  EEA18761.1 220 MVKETAPLIHGAVQILDGVEHdSRRSDVNEGFREILKAMEVIEASMEDMWKNSKPAD-YLTFRVFIFGITSQS--MFPNGVIYEGIN--DSHPMYFRGE 313
                 *******************5547799****************************986.899*******55554..48********76..466799**** PP

                 GGGG-HHHHHHHHHTT--TT.............S.SSHHHHHHHHHGGGS-HHHHHHHHHHHT...S--HHHHHHHTT-HH...HHHHHHHHHHHHHHH CS
         IDO 263 SagQSsliqalDvfLgvehertgekaaeakkesekkkaeesFleemrkYmPgphrrFLehles...aasirelvlsaeseeeeelreaYnaaveaLkel 358
                 S +  s+i +lD +L++    t                 ++ l+e r+Y P+phr+FL+++++   + +ire++++ ++      +  Y ++++ ++++
  EEA18761.1 314 SGANDSIIPLLDHLLQIPMPDTP---------------LTKILHEFRAYRPRPHREFLSYVANtaeKLNIREFAVQDDE-----TAILYLKTLDHVRSF 392
                 *****************999422...............36789******************87422479*****44443.....5789*********** PP

                 HHHHHHHHHHHTHHHHHH. CS
         IDO 359 RdkHikivtlYivlparka 377
                 R +H   +  Yi+   ++ 
  EEA18761.1 393 RWRHWLFAREYIIRRTSHP 411
                 *************987764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (498 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       504  (0.0281109); expected 358.6 (0.02)
Passed bias filter:                      485  (0.0270511); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.42
# Mc/sec: 3531.59
//
Query:       EEA18762.1  [L=589]
Description: Leucine Rich Repeat domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.2e-11   44.1   1.2    2.9e-11   42.9   1.2    1.7  1  F-box       F-box domain
    6.2e-09   35.6   0.9    1.4e-08   34.5   0.9    1.5  1  F-box-like  F-box-like
    0.00012   22.3   3.1     0.0015   18.8   0.3    2.7  2  TPR_12      Tetratricopeptide repeat
    0.00014   21.7   8.0        0.1   12.7   0.2    3.5  3  TPR_2       Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.011   15.7   2.4        3.1    8.1   0.0    3.2  3  TPR_7       Tetratricopeptide repeat
      0.017   14.9   7.6      0.065   13.0   0.0    4.7  4  LRR_8       Leucine rich repeat
      0.018   15.2   1.2        7.4    7.1   0.1    3.3  3  PPR         PPR repeat
      0.027   14.3   8.1        1.9    8.5   0.1    3.4  3  TPR_1       Tetratricopeptide repeat
      0.028   14.1   0.1       0.11   12.2   0.1    2.0  2  TPR_11      TPR repeat
      0.034   13.1   1.9      0.049   12.5   1.9    1.1  1  NARP1       NMDA receptor-regulated protein 1
      0.036   14.6   2.8        4.7    7.8   1.1    2.5  2  TPR_19      Tetratricopeptide repeat
      0.087   13.3  20.2         42    4.8   2.2    7.4  8  LRR_4       Leucine Rich repeats (2 copies)
      0.097   13.3   3.2        1.2    9.8   0.0    2.5  2  TPR_16      Tetratricopeptide repeat
       0.12   12.2   0.5        2.1    8.1   0.1    2.3  2  DUF5113     Domain of unknown function (DUF5113)
       0.13   13.2   1.3         14    6.9   0.0    3.2  3  TPR_14      Tetratricopeptide repeat
       0.15   12.5   3.3        2.6    8.5   0.9    2.4  2  BTAD        Bacterial transcriptional activator domain
       0.18   12.1   3.0        5.1    7.4   0.2    2.6  2  ANAPC3      Anaphase-promoting complex, cyclosome, subunit 3
        5.4    7.5   5.5          2    8.9   0.1    2.9  3  TPR_8       Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.9   1.2   2.9e-14   2.9e-11       2      43 ..     163     204 ..     162     209 .. 0.92

  Alignments for each domain:
  == domain 1  score: 42.9 bits;  conditional E-value: 2.9e-14
                 HHHHS-HHHHHHHHHTS-HHHHHHHCTT-HHHHHHHTTHHHH CS
       F-box   2 tlsrLPsevlrhILerLplsdllalrrVSkgwrilidsdrlw 43 
                 ++++L s++l++IL++Lp++ +++l rVSk wri+i++  + 
  EEA18762.1 163 PIFSLNSDCLLQILQHLPFRQIVSLTRVSKAWRIYIKDQPIL 204
                 89***********************************98765 PP

>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.5   0.9   1.4e-11   1.4e-08       7      47 ..     170     210 ..     168     211 .. 0.95

  Alignments for each domain:
  == domain 1  score: 34.5 bits;  conditional E-value: 1.4e-11
  F-box-like   7 EiLlqIFsyLppsdLlrlalVCrrWrrvaldtplLWrrlvl 47 
                 + LlqI+++Lp++++++l++V++ Wr  + d p LW+ +++
  EEA18762.1 170 DCLLQILQHLPFRQIVSLTRVSKAWRIYIKDQPILWSDISF 210
                 68***********************************9987 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.3   1.5e-06    0.0015       6      70 ..      39      96 ..      37     103 .. 0.87
   2 !   10.0   0.3   0.00085      0.85       9      72 ..      77     132 ..      70     135 .. 0.82

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 1.5e-06
      TPR_12  6 lnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlellee 70
                +++ ++ l+r g+y+eA++ l +al +        + +t+ ++   + +y ++g ye+Al+  ++
  EEA18762.1 39 YHQHGQDLARKGKYEEAIQVLTEALLQK-------NTDTVKIMDSRSAVYCRMGMYEKALSDAKH 96
                6789999*****************8888.......3359********************987665 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00085
      TPR_12   9 laavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleeal 72 
                 + av++r+g y++Al+  ++ +++a +   +        +   g ++++++++e+Al+++  al
  EEA18762.1  77 RSAVYCRMGMYEKALSDAKHMIRAAAKD--ERG------YLRAGKALLLAEKPEKALDIYAYAL 132
                 5689*****************9999443..433......7889999999999999999997665 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   0.2    0.0001       0.1       8      29 ..      43      64 ..      37      69 .. 0.88
   2 ?    5.7   0.0     0.018        18       7      25 ..      77      95 ..      71     103 .. 0.82
   3 ?    5.5   1.3     0.021        21       3      29 ..     107     133 ..     105     135 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 0.0001
       TPR_2  8 GlayyklgdyeeAleafekAle 29
                G+ ++++g+yeeA++ + +Al 
  EEA18762.1 43 GQDLARKGKYEEAIQVLTEALL 64
                8899****************96 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.018
       TPR_2  7 lGlayyklgdyeeAleafe 25
                +  +y ++g ye+Al + +
  EEA18762.1 77 RSAVYCRMGMYEKALSDAK 95
                7789**********98766 PP

  == domain 3  score: 5.5 bits;  conditional E-value: 0.021
       TPR_2   3 alynlGlayyklgdyeeAleafekAle 29 
                 ++ + G+a++ + ++e+Al+ +  Al+
  EEA18762.1 107 GYLRAGKALLLAEKPEKALDIYAYALK 133
                 68899*****************99997 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.0    0.0031       3.1      10      26 ..      47      63 ..      43      72 .. 0.80
   2 ?    5.8   0.0     0.016        16       8      31 ..      80     104 ..      78     107 .. 0.77
   3 ?   -1.8   0.1       4.3   4.3e+03       8      26 ..     114     132 ..     108     137 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0031
       TPR_7 10 srlGdyeeAielyeqsL 26
                 r G+yeeAi++++++L
  EEA18762.1 47 ARKGKYEEAIQVLTEAL 63
                578************55 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.016
       TPR_7   8 lysrlGdyeeAielyeqsL.altkd 31 
                 +y+r+G ye+A++  + ++ a +kd
  EEA18762.1  80 VYCRMGMYEKALSDAKHMIrAAAKD 104
                 6**********98777766666665 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 4.3
       TPR_7   8 lysrlGdyeeAielyeqsL 26 
                 +     + e+A+++y  +L
  EEA18762.1 114 ALLLAEKPEKALDIYAYAL 132
                 5555567799999998744 PP

>> LRR_8  Leucine rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.3      0.48   4.8e+02      25      58 ..     255     288 ..     232     289 .. 0.62
   2 ?    1.5   0.4      0.26   2.5e+02      21      53 ..     275     308 ..     255     313 .. 0.66
   3 ?   13.0   0.0   6.6e-05     0.065      17      48 ..     370     400 ..     367     412 .. 0.86
   4 ?    0.3   0.0       0.6     6e+02       2      21 ..     504     523 ..     503     546 .. 0.49

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.48
                 TT--EEE--SS---GGGGGGGTT--S-.EEE--S CS
       LRR_8  25 snLkvLdLsnNllttlspgafsgLpsLrsLdLsg 58 
                 ++L+++d+   l ++   + f++ ++L+sL Ls+
  EEA18762.1 255 PRLEHIDIDGALGESHIFNLFRDKHNLKSLILSN 288
                 5555555555544442235566666666666654 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.26
                 STT-TT--EEE--SS.---GGGGGGGTT--S-.E CS
       LRR_8  21 FkglsnLkvLdLsnN.llttlspgafsgLpsLrs 53 
                 F++ +nLk+L Lsn   l++    +++gLp+L+ 
  EEA18762.1 275 FRDKHNLKSLILSNKiPLSRHMLWTMVGLPNLER 308
                 6666677777777654444433445555555555 PP

  == domain 3  score: 13.0 bits;  conditional E-value: 6.6e-05
                 -TTSSTT-TT--EEE--SS---GGGGGGGTT- CS
       LRR_8  17 ddeaFkglsnLkvLdLsnNllttlspgafsgL 48 
                 ++++F +++nL++L Ls N+ + + + +f+g 
  EEA18762.1 370 PQSWFDRVPNLQELRLSANEGENI-RVCFDGI 400
                 689*********************.5999985 PP

  == domain 4  score: 0.3 bits;  conditional E-value: 0.6
                 T-SEEE-TTS--SEE-TTSS CS
       LRR_8   2 nLtsLdLsnNrltslddeaF 21 
                 nL++L+L+   + +l+ ++ 
  EEA18762.1 504 NLRELHLCGMGFYDLENSVV 523
                 55666665555555544433 PP

>> PPR  PPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.0     0.038        38      10      25 ..      46      61 ..      46      63 .. 0.87
   2 ?    7.1   0.1    0.0074       7.4       9      21 ..      80      92 ..      79      92 .. 0.91
   3 ?   -1.2   0.0       3.2   3.2e+03      12      23 ..     117     128 ..     107     129 .. 0.79

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.038
         PPR 10 ycknGkleeAlelfke 25
                ++++Gk+eeA++++ e
  EEA18762.1 46 LARKGKYEEAIQVLTE 61
                689********99865 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0074
         PPR  9 gycknGkleeAle 21
                +yc+ G++e+Al+
  EEA18762.1 80 VYCRMGMYEKALS 92
                6**********96 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 3.2
         PPR  12 knGkleeAlelf 23 
                  + k+e+Al+++
  EEA18762.1 117 LAEKPEKALDIY 128
                 567899999987 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.1    0.0019       1.9      10      28 ..      45      63 ..      43      67 .. 0.86
   2 ?    4.9   0.0     0.026        26      10      23 ..      80      93 ..      79      98 .. 0.88
   3 ?    3.3   1.2      0.08        80       4      29 ..     108     133 ..     106     133 .. 0.86

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.0019
                HHHHTT-HHHHHHHHHHHH CS
       TPR_1 10 ayfklgkydeAleyyekAL 28
                 + ++gky+eA++   +AL
  EEA18762.1 45 DLARKGKYEEAIQVLTEAL 63
                57789**********9998 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.026
                HHHHTT-HHHHHHH CS
       TPR_1 10 ayfklgkydeAley 23
                +y ++g+y++Al +
  EEA18762.1 80 VYCRMGMYEKALSD 93
                799********976 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.08
                 HHHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1   4 lynlGnayfklgkydeAleyyekALe 29 
                 + + G a++  +k+++Al+ y  AL+
  EEA18762.1 108 YLRAGKALLLAEKPEKALDIYAYALK 133
                 778899*************9987775 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.1   0.00011      0.11       1      21 [.      43      63 ..      43      69 .. 0.87
   2 ?   -2.1   0.0       3.3   3.3e+03       4      14 ..      81      91 ..      80      92 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00011
      TPR_11  1 GdayyeqGkyeeAieaYkkAl 21
                G+ +  +GkyeeAi+++ +Al
  EEA18762.1 43 GQDLARKGKYEEAIQVLTEAL 63
                677889***********9998 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 3.3
      TPR_11  4 yyeqGkyeeAi 14
                y+  G ye+A+
  EEA18762.1 81 YCRMGMYEKAL 91
                88899999997 PP

>> NARP1  NMDA receptor-regulated protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   1.9   4.9e-05     0.049      15     110 ..      47     146 ..      42     155 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 4.9e-05
                 HHHTHHHHHHHHHHH.HGGG---HHHHHHHHHHHHHHTT-HHHHHHHHHHHHHH-TT-CHHHHHHHHHT..SSS-HHHHHHHH....HHTTTS-TT-SH CS
       NARP1  15 eeagkleeAlehLee.kekqivDklavketkaelllkLgrkeeAeatyeaLlernpenskYyeglekakklskedeeallaly....delaekyprsda 108
                 + +gk+eeA++ L+e   ++ +D++++++ ++ +++++g++e+A +  +++++  + +++ y +  ka+ l+++  e+ l++y    ++l e++p+ +a
  EEA18762.1  47 ARKGKYEEAIQVLTEaLLQKNTDTVKIMDSRSAVYCRMGMYEKALSDAKHMIRAAAKDERGYLRAGKALLLAEK-PEKALDIYayalKSLGEQHPHKEA 144
                 6789*********98457899*******************************9988777777777777755555.445555551111566666676666 PP

                 HH CS
       NARP1 109 pr 110
                 ++
  EEA18762.1 145 VT 146
                 65 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.0     0.021        21       4      20 ..      49      65 ..      46      73 .. 0.61
   2 ?    7.8   1.1    0.0047       4.7       4      54 ..      84     134 ..      82     145 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.021
      TPR_19  4 egdyaeAlalleqalqe 20
                 g+y+eA++ l++al +
  EEA18762.1 49 KGKYEEAIQVLTEALLQ 65
                46777777777776433 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0047
      TPR_19   4 egdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpee 54 
                 +g y+ Al+  + ++ +++k+++  l+  +all +  +++A ++ + ++++
  EEA18762.1  84 MGMYEKALSDAKHMIRAAAKDERGYLRAGKALLLAEKPEKALDIYAYALKS 134
                 7999**************************************998877665 PP

>> LRR_4  Leucine Rich repeats (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0      0.11   1.1e+02       4      32 ..     234     264 ..     229     269 .. 0.67
   2 ?    4.6   0.3     0.048        48       2      30 ..     280     311 ..     279     318 .. 0.72
   3 ?    1.3   0.5       0.5     5e+02      20      32 ..     324     337 ..     304     344 .. 0.66
   4 ?    4.0   0.0      0.07        70      22      33 ..     377     388 ..     359     394 .. 0.81
   5 ?    0.5   0.0      0.89   8.9e+02       2      36 ..     404     436 ..     403     444 .. 0.65
   6 ?   -1.2   0.0       3.2   3.2e+03       4      32 ..     426     457 ..     423     463 .. 0.50
   7 ?    4.8   2.2     0.042        42       3      33 ..     476     513 ..     475     521 .. 0.76
   8 ?    3.7   0.1      0.09        89       1      30 [.     503     538 ..     503     551 .. 0.68

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.11
                 -EEE--SS---E-S-HH.....H.-TT--EEE-.- CS
       LRR_4   4 evLdLsnNqltdiplle.....k.lpnLkeLdLsg 32 
                 + L L+n  ++d  +l+     + +p L+++d+ g
  EEA18762.1 234 KRLQLHN--VRD--PLNaalqaSrCPRLEHIDIDG 264
                 4455555..555..4556667866********955 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.048
                 S--EEE--SS---E-S-..HH...H-TT--EEE- CS
       LRR_4   2 nLevLdLsnNqltdipl..le...klpnLkeLdL 30 
                 nL++L Lsn ++  ++   l+   +lpnL+ + +
  EEA18762.1 280 NLKSLILSN-KIP-LSRhmLWtmvGLPNLERIEV 311
                 9999****7.544.22236668878999988765 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.5
                 H.H.-TT--EEE-.- CS
       LRR_4  20 e.k.lpnLkeLdLsg 32 
                 e + l nLk+L+L +
  EEA18762.1 324 EvGvLLNLKSLTL-N 337
                 245599*****99.4 PP

  == domain 4  score: 4.0 bits;  conditional E-value: 0.07
                 -TT--EEE-.-S CS
       LRR_4  22 lpnLkeLdLsgN 33 
                  pnL+eL Ls N
  EEA18762.1 377 VPNLQELRLSAN 388
                 699999999888 PP

  == domain 5  score: 0.5 bits;  conditional E-value: 0.89
                 S--EEE--SS---E-S-HHH-TT.--EEE-.-S--- CS
       LRR_4   2 nLevLdLsnNqltdiplleklpn.LkeLdLsgNnli 36 
                 nL+++ Ls   ++ + + +k+p+  ++L+L ++n +
  EEA18762.1 404 NLRTVQLSR--IS-LYGTWKCPDtVEHLYLIDCNML 436
                 666666665..55.4445578888888988777665 PP

  == domain 6  score: -1.2 bits;  conditional E-value: 3.2
                 -EEE--S.S---E-S-..HHH-TT--EEE-.- CS
       LRR_4   4 evLdLsn.Nqltdipl..leklpnLkeLdLsg 32 
                 e+L+L + N+l + +   ++ l  L++L L g
  EEA18762.1 426 EHLYLIDcNMLPSSDIsmPQALLYLRTLVLRG 457
                 55555531233343333344455566666655 PP

  == domain 7  score: 4.8 bits;  conditional E-value: 0.042
                 --EEE--S..S.---E-S-HH...H.-TT--EEE-.-S CS
       LRR_4   3 LevLdLsn..N.qltdiplle...k.lpnLkeLdLsgN 33 
                 Le+L + n  N ++ d++ll    +  +nL+eL+L g+
  EEA18762.1 476 LETLQIENcdNvNVADLSLLTtndNvVKNLRELHLCGM 513
                 788888864466799999988888889*******9887 PP

  == domain 8  score: 3.7 bits;  conditional E-value: 0.09
                 SS--EEE--SS---E-S-...HH..H.-TT--EEE- CS
       LRR_4   1 pnLevLdLsnNqltdipl...le..k.lpnLkeLdL 30 
                 +nL++L+L +    d+++   l+    +p+LkeL++
  EEA18762.1 503 KNLRELHLCGMGFYDLENsvvLAmlAlMPQLKELHI 538
                 689999998855555555444335544999999987 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0    0.0012       1.2       2      24 ..      41      63 ..      40      71 .. 0.82
   2 ?    2.4   1.6      0.25   2.5e+02      15      59 ..      93     133 ..      86     141 .. 0.61

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.0012
      TPR_16  2 alaraalragdyddAaaaleaal 24
                +++++++r g+y++A+ +l++al
  EEA18762.1 41 QHGQDLARKGKYEEAIQVLTEAL 63
                5899***************6665 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.25
      TPR_16  15 dAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAa.alyra 59 
                 dA ++ +aa k+      +   + +++++++++++ a+ + a+ ++
  EEA18762.1  93 DAKHMIRAAAKDE-----RGYLRAGKALLLAEKPEKALDIyAYALK 133
                 7777887777777.....5555555555555555555555444444 PP

>> DUF5113  Domain of unknown function (DUF5113)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.1    0.0022       2.1       9      49 ..      37      77 ..      34      98 .. 0.80
   2 ?    1.8   0.0      0.19   1.9e+02      10      42 ..     107     139 ..      98     159 .. 0.84

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0022
     DUF5113  9 ndYanlayylnvegeyeeALeyldsaleylNahyekYakkk 49
                ++Y + ++ l  +g+yeeA+++l++al   N+   k ++++
  EEA18762.1 37 EKYHQHGQDLARKGKYEEAIQVLTEALLQKNTDTVKIMDSR 77
                58999**********************99887766666655 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.19
     DUF5113  10 dYanlayylnvegeyeeALeyldsaleylNahy 42 
                  Y  ++++l   +++e+AL++ + al+ l + +
  EEA18762.1 107 GYLRAGKALLLAEKPEKALDIYAYALKSLGEQH 139
                 58889999999****************998766 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.0     0.014        14       8      30 ..      43      65 ..      36      74 .. 0.80
   2 ?    1.6   0.1      0.66   6.5e+02       9      43 ..      79     113 ..      76     114 .. 0.83
   3 ?    2.8   0.3      0.28   2.8e+02       4      25 ..     108     129 ..     105     145 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.014
      TPR_14  8 aeallalGdpdeAiallrralal 30
                ++ l++ G+++eAi++l +al +
  EEA18762.1 43 GQDLARKGKYEEAIQVLTEALLQ 65
                567899***********999653 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.66
      TPR_14   9 eallalGdpdeAiallrralalaPddaeawlllaq 43 
                 +++ + G +++A+  ++ ++++a +d++ +l+ ++
  EEA18762.1  79 AVYCRMGMYEKALSDAKHMIRAAAKDERGYLRAGK 113
                 57788999999999999999999999999988775 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.28
      TPR_14   4 llalaeallalGdpdeAiallr 25 
                 +l++++all +++p++A++++ 
  EEA18762.1 108 YLRAGKALLLAEKPEKALDIYA 129
                 889999***********99885 PP

>> BTAD  Bacterial transcriptional activator domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.1     0.068        68       7      33 ..      37      63 ..      33      66 .. 0.90
   2 ?    8.5   0.9    0.0026       2.6      61     129 ..      70     138 ..      65     152 .. 0.89

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.068
                HHHHHHHHHHHHTT-HHHHHHHHHHHH CS
        BTAD  7 ealvaagraalaagdpeeaaelleaAl 33
                e++ + g++++++g+ eea++ l +Al
  EEA18762.1 37 EKYHQHGQDLARKGKYEEAIQVLTEAL 63
                778899*******************98 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0026
                 HHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHSTT-HHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHH CS
        BTAD  61 rlealealaeaelrlGraeealaelealvaehPlrErlhrqlmrAlarsGrqaeALevYerlrrlLaee 129
                  ++++ ++ +   r+G +e+al++++ ++++   +Er +    +Al   ++ ++AL  Y  + ++L e+
  EEA18762.1  70 TVKIMDSRSAVYCRMGMYEKALSDAKHMIRAAAKDERGYLRAGKALLLAEKPEKALDIYAYALKSLGEQ 138
                 56778888888899*********************************************9999998765 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.2    0.0051       5.1      26      55 ..      39      68 ..      35      91 .. 0.76
   2 ?    4.2   0.6     0.052        51      32      78 ..      80     127 ..      76     131 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0051
                HHHHHHHHHHTT-HHHHHHHHHCTSHHHC- CS
      ANAPC3 26 ayllAlclylngqykrAyellrkaklnsks 55
                 + +++ l + g+y++A+++l +a l++++
  EEA18762.1 39 YHQHGQDLARKGKYEEAIQVLTEALLQKNT 68
                67899999*************999444444 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.052
                 HHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHH CS
      ANAPC3  32 clylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaa 78 
                 +++++g y++A+  ++ + + + k+++  + ++++ll  +k e+A+++
  EEA18762.1  80 VYCRMGMYEKALSDAKHMiRAAAKDERGYLRAGKALLLAEKPEKALDI 127
                 799999999999999999777777776666666888888999999886 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.1     0.002         2       6      28 ..      41      63 ..      39      69 .. 0.81
   2 ?   -0.8   0.1       2.5   2.5e+03      13      26 ..      83      96 ..      78     104 .. 0.64
   3 ?   -0.9   0.4       2.7   2.7e+03       3      25 ..     107     129 ..     105     137 .. 0.78

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.002
                HHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_8  6 nlgsiylklgdyeeAkeyyekal 28
                + g+ +  +g+yeeA++++ +al
  EEA18762.1 41 QHGQDLARKGKYEEAIQVLTEAL 63
                555557789************98 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 2.5
                HTT-HHHHHHHHHH CS
       TPR_8 13 klgdyeeAkeyyek 26
                 +g ye+A +  ++
  EEA18762.1 83 RMGMYEKALSDAKH 96
                56777777766555 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 2.7
                 HHHHHHHHHHHTT-HHHHHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAkeyye 25 
                  y++ g+++l  ++ e+A   y 
  EEA18762.1 107 GYLRAGKALLLAEKPEKALDIYA 129
                 68888999998899999888775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (589 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       472  (0.0263261); expected 358.6 (0.02)
Passed bias filter:                      441  (0.024597); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                        18  (0.00100396); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              18  [number of targets reported over threshold]
# CPU time: 0.64u 0.30s 00:00:00.94 Elapsed: 00:00:00.47
# Mc/sec: 3796.74
//
Query:       EEA18763.1  [L=533]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.8e-41  140.4  17.0    4.8e-41  140.4  17.0    2.0  2  ADIP             Afadin- and alpha -actinin-Binding
     0.0034   16.9  15.7     0.0034   16.9  15.7    2.2  2  Golgin_A5        Golgin subfamily A member 5
  ------ inclusion threshold ------
      0.013   16.6   5.5      0.013   16.6   5.5    3.6  4  SOGA             Protein SOGA
      0.047   13.7   0.7       0.13   12.2   0.7    1.8  1  RepA_C           Plasmid encoded RepA protein
       0.21   11.4   1.5       0.71    9.7   1.5    2.0  1  sCache_2         Single Cache domain 2
       0.23   10.7   6.4       0.46    9.7   6.4    1.6  1  TMPIT            TMPIT-like protein
       0.28   11.5   9.8        0.6   10.4   2.1    3.5  3  Rx_N             Rx N-terminal domain
       0.37   10.7   3.2         17    5.4   0.1    2.7  2  HU-CCDC81_bac_2  CCDC81-like prokaryotic HU domain 2
       0.48    9.9   6.8        1.2    8.5   6.8    1.7  1  FAP206           Domain of unknown function
        1.3    9.4  11.1        1.7    9.0   7.6    2.8  2  KxDL             Uncharacterized conserved protein
        1.7    6.4  15.5       0.21    9.4   9.6    1.9  1  Nup88            Nuclear pore component
        5.3    5.8  22.9       0.08   11.8  14.9    2.0  2  Spc7             Spc7 kinetochore protein
          6    7.2  12.3         38    4.6   0.1    3.7  3  DUF948           Bacterial protein of unknown function (DUF94


Domain annotation for each model (and alignments):
>> ADIP  Afadin- and alpha -actinin-Binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.4  17.0   3.5e-44   4.8e-41       1     152 []       7     163 ..       7     163 .. 0.99
   2 ?   -3.0   0.4       5.1     7e+03     101     114 ..     475     488 ..     448     515 .. 0.55

  Alignments for each domain:
  == domain 1  score: 140.4 bits;  conditional E-value: 3.5e-44
        ADIP   1 enaikyINstLlsrGylrskllfdta.....tekveeniaaiinviysLlqardrdleqreslnetirkleaeierlqskierlktqleqlerelalvq 94 
                 e+a+ yIN+ Ll+rG+l++++ +++a     +e++  ++a+iin++++L+++r+r++e+re+l+ tir+l+ + +++  +ie+lkt++e+l+r +al++
  EEA18763.1   7 EAASNYINNLLLARGLLKNGKPINFAqpdnaDEGSDATMAQIINLVNDLVVRREREAEHRENLASTIRNLRVTESQQVDDIEKLKTKNEELKRSVALAE 105
                 689************************************************************************************************ PP

        ADIP  95 akerqlekklktleqklknekeelqrlknalqqiktqyahelkkkdreiekLkeklke 152
                  ++r ++++l ++e++++++ke++q+lk+++qq+++q+a++ +k+d+e++kLk +l+e
  EEA18763.1 106 GQQRVMKQNLSSAETTVRQLKEQVQKLKTTVQQVRAQCANDARKRDTELQKLKTHLSE 163
                 *******************************************************986 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 5.1
        ADIP 101 ekklktleqklkne 114
                 + kl++ e+ +k+ 
  EEA18763.1 475 QEKLAAVEAEAKEA 488
                 22222222222222 PP

>> Golgin_A5  Golgin subfamily A member 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9  15.7   2.4e-06    0.0034      55     159 ..      54     165 ..      27     170 .. 0.63
   2 ?   -2.3   2.4       1.8   2.4e+03     103     132 ..     465     494 ..     404     529 .. 0.45

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 2.4e-06
   Golgin_A5  55 erdllreelqklnqqieqlrtelqdleaqqqaeaeslreqlqel.......eeqleeerkakeeveaelerlkeelryleeelvrskatlqsrikdrek 146
                 +  + re  ++ ++++ +   +l+ +e+qq  ++e+l+ +++el       e q++  +++  ++e+ +++lke+++ l+  +++++a++ +  ++r++
  EEA18763.1  54 DLVVRREREAEHRENLASTIRNLRVTESQQVDDIEKLKTKNEELkrsvalaEGQQRVMKQNLSSAETTVRQLKEQVQKLKTTVQQVRAQCANDARKRDT 152
                 3333344444444444444444444555555555555555555500000005555666666677888899999999999999999999999******** PP

   Golgin_A5 147 eieklrnqlttks 159
                 e++kl+  l+ ++
  EEA18763.1 153 ELQKLKTHLSERQ 165
                 ********99876 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1.8
   Golgin_A5 103 eeerkakeeveaelerlkeelryleeelvr 132
                 +++ kak +++++l+ ++ e + + ee + 
  EEA18763.1 465 QTNPKAKLSIQEKLAAVEAEAKEAAEEATG 494
                 222222222222222222222222222222 PP

>> SOGA  Protein SOGA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   16.6   5.5   9.7e-06     0.013       2      72 ..      94     162 ..      93     174 .. 0.84
   2 ?   -2.3   0.0       7.6     1e+04      13      35 ..     202     224 ..     199     250 .. 0.70
   3 ?   -1.7   0.0       4.9   6.8e+03      58      81 ..     369     392 ..     354     399 .. 0.55
   4 ?    0.5   0.4         1   1.4e+03      48      80 ..     455     487 ..     427     505 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 9.7e-06
        SOGA   2 aaeLrrhLqfveeEaeLlrrslseleeenkqlteeLnkyksklgeeessleeeeeassdsskeaelkeeLk 72 
                 ++eL+r   ++e    +++++ls  e   +ql+e+++k+k+  ++++++ ++   a +  ++ ++lk +L 
  EEA18763.1  94 NEELKRSVALAEGQQRVMKQNLSSAETTVRQLKEQVQKLKTTVQQVRAQCAN--DARKRDTELQKLKTHLS 162
                 68********************************************999987..34444455666666664 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 7.6
        SOGA  13 eeEaeLlrrslseleeenkqlte 35 
                 +e +e l +   +l +en+ l +
  EEA18763.1 202 QETTEFLTQLCQNLSDENDTLIN 224
                 46677777777788888887754 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 4.9
        SOGA  58 ssdsskeaelkeeLklarlqineL 81 
                 +++++  +e +ee + a+ q+++L
  EEA18763.1 369 EDEEQGDQEAEEEDEIAEPQAKIL 392
                 222333445555555666666655 PP

  == domain 4  score: 0.5 bits;  conditional E-value: 1
        SOGA  48 essleeeeeassdsskeaelkeeLklarlqine 80 
                 +s  ++++  +++ + + +++e+L +++ +++e
  EEA18763.1 455 PSRRASSQIPQTNPKAKLSIQEKLAAVEAEAKE 487
                 344444445555666777889999999988876 PP

>> RepA_C  Plasmid encoded RepA protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.7   9.6e-05      0.13      47     100 ..     117     170 ..      87     181 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 9.6e-05
      RepA_C  47 GarGtlkdireqvsriaaceltvrwedaeslgdektailedkilfederdseqg 100
                  a  t+++++eqv+++ ++  +vr + a+++++++t++ + k + ++ +  +++
  EEA18763.1 117 SAETTVRQLKEQVQKLKTTVQQVRAQCANDARKRDTELQKLKTHLSERQRGKRE 170
                 34579***********************************99999887766655 PP

>> sCache_2  Single Cache domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   1.5   0.00052      0.71       7      49 ..     123     165 ..      91     184 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00052
    sCache_2   7 aelknqvetaislieavykqvesgkiteeeaqeevkelvnglk 49 
                 ++lk+qv+++ +++++v++q+++ +  ++   ++ k+++++ +
  EEA18763.1 123 RQLKEQVQKLKTTVQQVRAQCANDARKRDTELQKLKTHLSERQ 165
                 5788888888888888888888888888888888887777655 PP

>> TMPIT  TMPIT-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   6.4   0.00033      0.46       9      79 ..      85     165 ..      51     194 .. 0.71

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00033
       TMPIT   9 kefkeleetakeykqkleelsklqskcskeikkqkkrlkelksslkklkksvk..........eeeeeeveelkeelkerk 79 
                 +++++l+++++e+k++++  + +q  +++++++ +  +++lk++++klk++v+          +++++e+++lk++l+er+
  EEA18763.1  85 DDIEKLKTKNEELKRSVALAEGQQRVMKQNLSSAETTVRQLKEQVQKLKTTVQqvraqcandaRKRDTELQKLKTHLSERQ 165
                 455566666666666666666666666666666666666666666666665543444444555666667777777777766 PP

>> Rx_N  Rx N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.4      0.39   5.4e+02      24      49 ..      84     109 ..      66     115 .. 0.81
   2 ?   10.4   2.1   0.00044       0.6      14      59 ..     116     162 ..     109     166 .. 0.83
   3 ?    2.9   0.0     0.094   1.3e+02      43      78 ..     246     281 ..     204     314 .. 0.74

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.39
        Rx_N  24 keeleklkdeLesiqavLedaeerqi 49 
                  +++eklk++ e ++  ++ ae +q+
  EEA18763.1  84 VDDIEKLKTKNEELKRSVALAEGQQR 109
                 47999999999999999999999887 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00044
        Rx_N  14 aeeakllkgvkeeleklkdeLesiqa.vLedaeerqikdeavkeWlk 59 
                 ++  + ++++ke+++klk++ ++++a + +da +r+++ + +k+ l+
  EEA18763.1 116 SSAETTVRQLKEQVQKLKTTVQQVRAqCANDARKRDTELQKLKTHLS 162
                 55558899*****************9677799999999898888776 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.094
        Rx_N  43 daeerqikdeavkeWlkelrdlaydaeDvlDefete 78 
                 da++   +  av +   ++ dl+ +++ vlD ++t 
  EEA18763.1 246 DASQSFSQGGAVSTIPTNVMDLSAEMDTVLDHLRTL 281
                 566666677889999999*************99876 PP

>> HU-CCDC81_bac_2  CCDC81-like prokaryotic HU domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.7     0.021        29       5      35 ..     108     138 ..     107     141 .. 0.90
   2 ?    5.4   0.1     0.012        17      24      53 ..     152     181 ..     147     184 .. 0.91

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.021
  HU-CCDC81_bac_2   5 nsiaeaegisyeeAlqkiekeveelkqeLee 35 
                      + +++++  s e+ +++++++v++lk + ++
       EEA18763.1 108 QRVMKQNLSSAETTVRQLKEQVQKLKTTVQQ 138
                      678999999*****************99886 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.012
  HU-CCDC81_bac_2  24 keveelkqeLeeegrveleniGeLslneeg 53 
                      +e ++lk +L e++r + e++G++++n ++
       EEA18763.1 152 TELQKLKTHLSERQRGKREGLGVITININR 181
                      6889***********************987 PP

>> FAP206  Domain of unknown function
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   6.8    0.0009       1.2       4     100 ..      71     165 ..      68     175 .. 0.91

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.0009
      FAP206   4 eaipatreaiekeleeaqelasrytalleklveeseaevaeeqlerlkqalinvrqyeaylrilledveksaeeveellkrfeaeleklketvkskt 100
                  +i+++r +  +++ ++++l ++  +l +++    ++ ++    ++l  a ++vrq++ +++ l++ v++ + ++ +   + ++el+klk  +++++
  EEA18763.1  71 STIRNLRVTESQQVDDIEKLKTKNEELKRSV--ALAEGQQRVMKQNLSSAETTVRQLKEQVQKLKTTVQQVRAQCANDARKRDTELQKLKTHLSERQ 165
                 6778888888899999999999999999999..788888889999999*********************************************9997 PP

>> KxDL  Uncharacterized conserved protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   7.6    0.0012       1.7      15      79 ..      80     144 ..      68     147 .. 0.91
   2 ?    0.1   0.1      0.75     1e+03      19      47 ..     209     237 ..     203     254 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.0012
        KxDL  15 lalQaqtsgrlnkknreLlelnalsqerlaklrarfkqgtkllkevkkdLesifkkirslkakla 79 
                  ++Q +   +l+ kn+eL++  al++ +   +++++ +  ++++++k++ ++++ ++++ +a+ a
  EEA18763.1  80 ESQQVDDIEKLKTKNEELKRSVALAEGQQRVMKQNLSSAETTVRQLKEQVQKLKTTVQQVRAQCA 144
                 567888889*************************************************9999876 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.75
        KxDL  19 aqtsgrlnkknreLlelnalsqerlaklr 47 
                 +q+ + l ++n +L +l   + + l +l+
  EEA18763.1 209 TQLCQNLSDENDTLINLSRTTIQTLRELQ 237
                 57788899999999999988888888776 PP

>> Nup88  Nuclear pore component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   9.6   0.00015      0.21     639     709 ..      64     136 ..      43     137 .. 0.89

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00015
       Nup88 639 eklkslknalkqvkkkldkqrkqiaks..keeekksslelsekqkktikeiLkeegeeieelikqvkdikkiv 709
                 e+ ++l+ ++++++ + ++q + i+k   k+ee k+s++l e q++++k++L+    ++++l +qv+++k++v
  EEA18763.1  64 EHRENLASTIRNLRVTESQQVDDIEKLktKNEELKRSVALAEGQQRVMKQNLSSAETTVRQLKEQVQKLKTTV 136
                 667899******************98633667789***********************************987 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8  14.9   5.8e-05      0.08     156     280 ..      43     166 ..      32     188 .. 0.81
   2 ?   -2.8   1.0       1.6   2.2e+03     226     253 ..     465     492 ..     426     516 .. 0.54

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 5.8e-05
        Spc7 156 elLekqeeeldellpeleeeka...eleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeia 251
                 +++++  +++++l+ + e+e +   +l +++++l+      es + +++e+l+ + +elk  ++  + +   ++++l + e+++ +lkeq ++l++ ++
  EEA18763.1  43 ATMAQIINLVNDLVVRREREAEhreNLASTIRNLRV----TESQQVDDIEKLKTKNEELKRSVALAEGQQRVMKQNLSSAETTVRQLKEQVQKLKTTVQ 137
                 455556666666655544443311133333333333....5677899**************************************************** PP

        Spc7 252 eaervleeckgwsesevsrlkeevkalee 280
                 + +  + +  + +++e+++lk+++++ ++
  EEA18763.1 138 QVRAQCANDARKRDTELQKLKTHLSERQR 166
                 **********************9987665 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1.6
        Spc7 226 qeqleeleekieelkeqkseleeeiaea 253
                 q++ +++ +  e+l++  +e++e+ +ea
  EEA18763.1 465 QTNPKAKLSIQEKLAAVEAEAKEAAEEA 492
                 3333333333333333333333333333 PP

>> DUF948  Bacterial protein of unknown function (DUF948)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   4.8     0.032        45      25      58 ..     112     145 ..      67     166 .. 0.80
   2 ?    4.6   0.1     0.027        38      18      67 ..     173     222 ..     171     236 .. 0.80
   3 ?    0.3   0.1      0.62   8.6e+02      35      60 ..     257     282 ..     220     285 .. 0.71

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.032
      DUF948  25 kktldeaaatieelekqvdpilkevedllakvne 58 
                 k+ l++a++t+++l++qv+++ + v+++ a+  +
  EEA18763.1 112 KQNLSSAETTVRQLKEQVQKLKTTVQQVRAQCAN 145
                 6678889999999999999999999888776555 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.027
      DUF948  18 ivvllklkktldeaaatieelekqvdpilkevedllakvnelledvnekl 67 
                  v+ +++++t+d++ ++  ++++   ++ +e+++ l++  + l+d n+ l
  EEA18763.1 173 GVITININRTADNTHKSAPDVKNPGYSLKQETTEFLTQLCQNLSDENDTL 222
                 56778999999999999999999999999999999988887777766655 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.62
      DUF948  35 ieelekqvdpilkevedllakvnell 60 
                 + ++  +v  ++ e++++l++ ++ll
  EEA18763.1 257 VSTIPTNVMDLSAEMDTVLDHLRTLL 282
                 44555777777777777777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (533 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2853  (0.159128); expected 358.6 (0.02)
Passed bias filter:                      873  (0.0486921); expected 358.6 (0.02)
Passed Vit filter:                       144  (0.00803168); expected 17.9 (0.001)
Passed Fwd filter:                        51  (0.00284455); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 1.02u 0.34s 00:00:01.36 Elapsed: 00:00:00.53
# Mc/sec: 3025.45
//
Query:       EEA18764.1  [L=88]
Description: cytochrome c oxidase assembly protein (Pet117), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      6e-26   90.5   1.8    6.9e-26   90.3   1.8    1.0  1  PET117    PET assembly of cytochrome c oxidase, mitochondrial
  ------ inclusion threshold ------
        0.1   11.4   0.2       0.13   11.1   0.2    1.1  1  PAP_PilO  Pilin accessory protein (PilO)


Domain annotation for each model (and alignments):
>> PET117  PET assembly of cytochrome c oxidase, mitochondrial
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.3   1.8   7.7e-30   6.9e-26       1      70 []       4      69 ..       4      69 .. 0.98

  Alignments for each domain:
  == domain 1  score: 90.3 bits;  conditional E-value: 7.7e-30
      PET117  1 AsKitLglsvlltaatvvgVHylQrlerealrqGvirDaerqaeKerkrkenkaeleeqkelrkkyekvQ 70
                AsK+tL++++l+ta+++++VH++Q+++r+a+++Gv rD+erq+ K    +e++a++e+q++l+++y+k+Q
  EEA18764.1  4 ASKVTLAVTSLATAGMIYFVHWSQEADRAAMHAGVERDEERQRIK----RERQADFEMQRRLEEEYRKIQ 69
                8********************************************....6******************98 PP

>> PAP_PilO  Pilin accessory protein (PilO)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.2   1.4e-05      0.13     168     214 ..       7      54 ..       2      61 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 1.4e-05
    PAP_PilO 168 valvlsllilgGlvgWrlyeakkeaeaqaa.laeavevqraqqaeeak 214
                 v+l ++ l+ +G++ ++ + +++ ++a  a  ++ +e+qr ++ ++a 
  EEA18764.1   7 VTLAVTSLATAGMIYFVHWSQEADRAAMHAgVERDEERQRIKRERQAD 54 
                 57889***************9999887655167778888888777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (88 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1025  (0.0571699); expected 358.6 (0.02)
Passed bias filter:                      530  (0.029561); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.40u 0.28s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 620.91
//
Query:       EEA18765.1  [L=117]
Description: vacuolar ATP synthase subunit G, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-32  112.4  18.2    1.6e-32  112.2  18.2    1.0  1  V-ATPase_G    Vacuolar (H+)-ATPase G subunit
     0.0042   16.5  13.1     0.0042   16.5  13.1    1.9  2  DUF3552       Domain of unknown function (DUF3552)
     0.0075   16.3  19.7      0.015   15.4  11.1    2.1  2  ATP-synt_B    ATP synthase B/B' CF(0)
  ------ inclusion threshold ------
      0.053   13.5   3.7      0.059   13.4   3.7    1.0  1  S_layer_C     S-layer like family, C-terminal region
      0.073   13.6   5.9       0.06   13.9   4.7    1.5  1  YusW          YusW-like protein
        0.2   12.1  16.5        0.3   11.5  16.5    1.3  1  V-ATPase_G_2  Vacuolar (H+)-ATPase G subunit
        1.3    8.7   9.7        1.4    8.6   9.7    1.0  1  ATP11         ATP11 protein
        8.8    4.1   7.8         10    3.9   7.8    1.0  1  V_ATPase_I    V-type ATPase 116kDa subunit family


Domain annotation for each model (and alignments):
>> V-ATPase_G  Vacuolar (H+)-ATPase G subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.2  18.2   7.1e-36   1.6e-32       1     105 []       4     108 ..       4     108 .. 0.99

  Alignments for each domain:
  == domain 1  score: 112.2 bits;  conditional E-value: 7.1e-36
                 -HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHSSHHHHHHHHHHHHHHHHHHHHHHH CS
  V-ATPase_G   1 sqsqgIqqLLqAEkeAaeivkeArkrkakrlkqAkeeAekEieeyrakkekefkekeaeklgseeelekkieketeekikelkesvkknkeavvkellk 99 
                 ++s+gIq+LL+AE+eA++iv++Ar++++kr+k+A++eA++Ei+ yr++ke+efk++eae++++++++e++++ke+e +++e+k + kk  ++v+k+l++
  EEA18765.1   4 QNSAGIQTLLDAEREAQKIVQQAREYRTKRVKEARTEAQREIDDYRKQKEEEFKKFEAEHSSGNKKAEEEANKEAEVQLAEIKVAGKKSGDKVIKDLIH 102
                 5899*********************************************************************************************** PP

                 HHTSXX CS
  V-ATPase_G 100 lvldvk 105
                 +v++vk
  EEA18765.1 103 AVVEVK 108
                 ***986 PP

>> DUF3552  Domain of unknown function (DUF3552)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5  13.1   1.9e-06    0.0042      26      83 ..       9      66 ..       2      71 .. 0.89
   2 ?    1.3   1.9     0.087     2e+02     158     174 ..      69      85 ..      64     107 .. 0.54

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 1.9e-06
     DUF3552 26 ekkiaeAeeeAkkiieeAkkeAeakkkealleakeeihklreelekelkerrnelqrl 83
                 + + +Ae+eA+ki+++A+    +  kea +ea+ ei ++r++ e+e+k+ ++e ++ 
  EEA18765.1  9 IQTLLDAEREAQKIVQQAREYRTKRVKEARTEAQREIDDYRKQKEEEFKKFEAEHSSG 66
                577889*******************************************999888765 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.087
     DUF3552 158 eveeelkheaAkmikei 174
                 ++eee+++ea +   ei
  EEA18765.1  69 KAEEEANKEAEVQLAEI 85 
                 33444444444444444 PP

>> ATP-synt_B  ATP synthase B/B' CF(0)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4  11.1   6.5e-06     0.015      57     106 ..       9      58 ..       1      65 [. 0.88
   2 !    6.4   1.7    0.0039       8.7      53      88 ..      68     103 ..      59     116 .. 0.75

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 6.5e-06
  ATP-synt_B  57 eqqlkeAraeAaeiiknAkkeaeklkeeieaeaeaeaerlkesAaaeIeq 106
                  q l +A++eA++i+++A++ + k  +e+++ea++e++  ++++++e ++
  EEA18765.1   9 IQTLLDAEREAQKIVQQAREYRTKRVKEARTEAQREIDDYRKQKEEEFKK 58 
                 57899***************************************999765 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.0039
  ATP-synt_B  53 laeaeqqlkeAraeAaeiiknAkkeaeklkeeieae 88 
                 ++++e++ keA+ + aei  ++kk++ k+ ++++ +
  EEA18765.1  68 KKAEEEANKEAEVQLAEIKVAGKKSGDKVIKDLIHA 103
                 567778888888888888888888888887776654 PP

>> S_layer_C  S-layer like family, C-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   3.7   2.6e-05     0.059      45     137 ..      13     106 ..       2     116 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 2.6e-05
   S_layer_C  45 kdeekledkvvglalkykgdkladikdkdkvdianyaklkfdD..klsvyfkideekevelivgekvkvlsadvkaekikakaeqvvkltaPivv 137
                  d e+  +k+v+ a  y+   +++ +++++ +i +y k k ++  k  ++ +   +k++e+  +++++v+ a++k+   k   ++ + l   +v 
  EEA18765.1  13 LDAEREAQKIVQQAREYRTKRVKEARTEAQREIDDYRKQKEEEfkKFEAEHSS-GNKKAEEEANKEAEVQLAEIKVAGKKSGDKVIKDLIHAVVE 106
                 45566789*****************************8888777777777776.788899999************98888777776666655555 PP

>> YusW  YusW-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   4.7   2.7e-05      0.06      18      73 ..      47     103 ..      36     113 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 2.7e-05
        YusW  18 eYekekdeteakie.dgankekleGdeAleelealLseLsvdsetsedevisqvlsa 73 
                 +Y+k+k+e+  k e ++ +++k   +eA +e e  L+e++v+ ++s d+vi+ ++ a
  EEA18765.1  47 DYRKQKEEEFKKFEaEHSSGNKKAEEEANKEAEVQLAEIKVAGKKSGDKVIKDLIHA 103
                 688888885555556999*********************************999865 PP

>> V-ATPase_G_2  Vacuolar (H+)-ATPase G subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5  16.5   0.00013       0.3       7     102 ..       9     104 ..       3     107 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00013
                   THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSHHHHHHHHHHHH CS
  V-ATPase_G_2   7 lkeLaerEaeLdqrlEaArkeaereveaAeaeAarilreAeakakalqaeyeqelaeevarireeararaeaeaqavrkraearlqqAvelilkaV 102
                   ++ L + E+e ++ + +Ar+   ++v++A+ eA+r + +  ++ ++  +++e+e +   ++ +eea+++ae +  +++ ++++  ++ ++  ++aV
    EEA18765.1   9 IQTLLDAEREAQKIVQQAREYRTKRVKEARTEAQREIDDYRKQKEEEFKKFEAEHSSGNKKAEEEANKEAEVQLAEIKVAGKKSGDKVIKDLIHAV 104
                   56777788888888999****************999888888888888888888888888999999999999888888888777777777777776 PP

>> ATP11  ATP11 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   9.7   0.00063       1.4       6      88 ..      18     100 ..      15     117 .] 0.57

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00063
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---.......SS--H CS
       ATP11   6 YreKLeqkakeeglesieeLkeaykdkieekrkeaaaidleesksesekekeakasssektekkesaakskkkskskspvkpL 88 
                  ++K+ q+a+e   + ++e +++++++i++ rk++++  ++ ++++s+ +k+a++++++++e + ++ k + k++ ++ +k L
  EEA18765.1  18 EAQKIVQQAREYRTKRVKEARTEAQREIDDYRKQKEEEFKKFEAEHSSGNKKAEEEANKEAEVQLAEIKVAGKKSGDKVIKDL 100
                 5799****************************999332222222222222222222222222222222222444444444444 PP

>> V_ATPase_I  V-type ATPase 116kDa subunit family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   7.8    0.0046        10     641     710 ..      32     104 ..       9     106 .. 0.45

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.0046
  V_ATPase_I 641 kkkkekkkeeee.......e...eeeeeeeeeeeeeeeaeeeeeeeeeeeeeeeeeeeeeeeeeefdfgevfihqvIhtI 710
                 k+ k       e       e    ++++eee ++ e e+++ ++++eee+++e+e + +e +   ++ g+ +i+ +Ih++
  EEA18765.1  32 KRVK-------EarteaqrEiddYRKQKEEEFKKFEAEHSSGNKKAEEEANKEAEVQLAEIKVAGKKSGDKVIKDLIHAV 104
                 1111.......011111111222222222222222222333333444444444444555555668888888999988875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (117 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2937  (0.163813); expected 358.6 (0.02)
Passed bias filter:                      866  (0.0483016); expected 358.6 (0.02)
Passed Vit filter:                       109  (0.00607954); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.66u 0.38s 00:00:01.04 Elapsed: 00:00:00.57
# Mc/sec: 613.20
//
Query:       EEA18766.1  [L=1496]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1496 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1235  (0.0688828); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 1.18u 0.38s 00:00:01.56 Elapsed: 00:00:00.62
# Mc/sec: 7238.27
//
Query:       EEA18767.1  [L=617]
Description: hypothetical protein PMAA_010480 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    7.9e-15   55.2   0.4    2.9e-13   50.1   0.1    2.8  2  Arrestin_N  Arrestin (or S-antigen), N-terminal domain
  ------ inclusion threshold ------
       0.12   11.8   0.0       0.25   10.7   0.0    1.5  1  Bul1_C      Bul1 C terminus


Domain annotation for each model (and alignments):
>> Arrestin_N  Arrestin (or S-antigen), N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.1   0.1   3.2e-17   2.9e-13       2     131 ..       4     172 ..       3     182 .. 0.84
   2 ?   -0.8   0.0      0.16   1.5e+03     100     135 ..     336     371 ..     333     378 .. 0.76

  Alignments for each domain:
  == domain 1  score: 50.1 bits;  conditional E-value: 3.2e-17
                 EEEES-SEEEEETT--EEEEEEE-CCCCTT.CEEEEEEEEEEEES....SSSTTTTCCCEEEEEEEEEEEEESTSSSSS.SSSSHHHHHHHH-TTEEEE CS
  Arrestin_N   2 tieldkrdevyhpgetvdGkvlleteelkkarkvkielsgkartg....weesevagktfrkdltlkkkqeyleteksllkskkdsqekLpkGehafpF 96 
                 ti+ldk++  +   + ++G+v+l+  ++  + ++ ++l+g+ rt+    ++++++++  ++ ++ l + ++++++ + +  s  ++  +L  G +++pF
  EEA18767.1   4 TIKLDKPHSHFTNLDHITGRVVLQLHSDTAISAIHVKLEGESRTRlltpRNDRDKKKAEIEVHKILYQVKAVFPSPDIAQHSSPNAAFTLAPGVYEYPF 102
                 799******99999*****************************98332245555556666666677777788888888888889*************** PP

                 EE---TTS--SE....................................CSGEEEEEEEEEEEEECCCE--C CS
  Arrestin_N  97 sfelPknlpsSf....................................eGkaggvrYevkvtldrpwkidk 131
                  f++P n  +S                                      G   +++Y+vk+t+ rp+ +++
  EEA18767.1 103 EFKFPFNNSCSNqnsmmtnlsmvglrvevardsyvhvkktlppslntfPG-EAEIKYYVKTTVVRPQFYKE 172
                 ***********999999999999999999999999999999999976433.45899999999999984443 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.16
                 --TTS--SECSGEEEEEEEEEEEEECCCE--C.CCE CS
  Arrestin_N 100 lPknlpsSfeGkaggvrYevkvtldrpwkidkkkkk 135
                 l +n+++Sfe    +  Ye++v +  +  +  ++  
  EEA18767.1 336 LRPNVAPSFETCNISRHYELEVRVGVSHGPAGRSMP 371
                 66899*****9999999**99998887766665554 PP

>> Bul1_C  Bul1 C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   2.8e-05      0.25     229     255 ..     336     362 ..     322     377 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 2.8e-05
      Bul1_C 229 lketlvPsFesClcsRlYcvrvnikfd 255
                 l+  + PsFe+C +sR Y + v +  +
  EEA18767.1 336 LRPNVAPSFETCNISRHYELEVRVGVS 362
                 556689************999988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (617 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       471  (0.0262703); expected 358.6 (0.02)
Passed bias filter:                      299  (0.0166769); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.78u 0.34s 00:00:01.12 Elapsed: 00:00:00.59
# Mc/sec: 3160.49
//
Query:       EEA18768.1  [L=325]
Description: triacylglycerol lipase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (325 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       606  (0.0338); expected 358.6 (0.02)
Passed bias filter:                      600  (0.0334653); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.68u 0.35s 00:00:01.03 Elapsed: 00:00:00.56
# Mc/sec: 1761.08
//
Query:       EEA18769.1  [L=557]
Description: AIF-like mitochondrial oxidoreductase (Nfrl), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.4e-49  167.7   0.1    4.3e-49  167.3   0.1    1.1  1  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    4.6e-15   55.9   0.4    3.9e-13   49.8   0.1    2.5  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
    1.1e-14   54.1   0.0    3.5e-14   52.5   0.0    1.8  2  Rieske         Rieske [2Fe-2S] domain
    9.3e-08   31.7   0.0     0.0017   17.7   0.0    2.2  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
    3.4e-06   26.9   0.0    1.7e-05   24.7   0.0    2.1  2  Rieske_2       Rieske-like [2Fe-2S] domain
    1.4e-05   25.5   0.0    5.4e-05   23.7   0.0    2.0  1  Reductase_C    Reductase C-terminal
    0.00024   21.1   0.1        0.6   10.1   0.0    2.6  3  NAD_binding_9  FAD-NAD(P)-binding
     0.0055   15.9   0.0          2    7.5   0.0    2.5  3  K_oxygenase    L-lysine 6-monooxygenase (NADPH-requiring)
  ------ inclusion threshold ------
      0.022   14.3   0.3       0.59    9.8   0.1    2.5  2  Kelch_1        Kelch motif
      0.024   14.2   0.1      0.041   13.4   0.1    1.3  1  DUF1188        Protein of unknown function (DUF1188)
      0.036   12.8   0.1        7.8    5.1   0.0    2.8  3  HI0933_like    HI0933-like protein
      0.053   12.6   0.1        1.1    8.3   0.0    2.6  3  GIDA           Glucose inhibited division protein A
      0.065   13.5   0.3        1.9    8.8   0.1    2.6  2  TrkA_N         TrkA-N domain
       0.13   11.5   0.0       0.21   10.9   0.0    1.2  1  Amino_oxidase  Flavin containing amine oxidoreductase


Domain annotation for each model (and alignments):
>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  167.3   0.1   3.4e-52   4.3e-49       2     294 .]     132     441 ..     131     441 .. 0.92

  Alignments for each domain:
  == domain 1  score: 167.3 bits;  conditional E-value: 3.4e-52
                  SEEEE--SHHHHHHHHHHHH..HTS-EEEEETTHCHHHCSHHHHCHHHHHHHHHHHHH....HHHHCHHHHCCCCHCCTCEEEEESCEEEEETEEECT CS
                  xxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2   2 dvvviGgGpAGlaaaltlaq..agakvtlvelegtclnggcllskallgvaedaeias....evvkklnqgielllgeevvkidpgkkkvklekkkeg 93 
                  +vvviGgG + + a +tl++   ++ ++l+ +e ++++++  lskal + a++ e +           n+gi+++++ ev+++d++ k v       +
   EEA18769.1 132 KVVVIGGGSGSIGAVQTLRElnFKGSIALITKEPNLPLDRTKLSKALIADASKIELRPaewyS-----NAGIDVVHD-EVTSVDFQTKSVST-----K 218
                  8*******************8779******************************998875541.....569******.*********99999.....5 PP

                  CEEEEEESEEEE---EEE-BCTCTTC..TTBEECCSECHHHHHHCCSS-T..SEEEEES-SHHHHHHHHHHHHHT-EEEEEESSSSSS.TTS-HHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxx RF
  Pyr_redox_2  94 deekiaydklvlAtGssprdlgipGv.aenvgklvrtldsaealklkllp..krivvvGgGyiGvElAaalaklgkevtlveardrll.raldkelsa 187
                  +++++ y klvlAtG+ pr+l+++G    ++++ +r +++++ + ++l +  k++v++G+++iG+E+  al+k  ++v +v   + +l r +++++++
   EEA18769.1 219 SGKSFSYTKLVLATGGIPRNLPLEGFkDLGNIFKLRFVTDVQSILRALGEekKKVVIIGSSFIGMEVGNALSKN-HDVSIVGMEKAPLeRVMGEKVGK 315
                  5679**********************533456677************99999******************9997.88********************* PP

                  HHHHHHHHTTEEEEESCEEEEEEETTE...EEE.EEETTSCEEEESEEEE-S-EEES-HHCSHCCT-EEEETTEEE--TTSBE.S.STTEEE-GGGC. CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxx...xxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.x.xxxxxxxxxxx. RF
  Pyr_redox_2 188 aleealekeGvevklgtsvkeidgnge...kle.vvledgeeidadlvvvavGvrpstelleeklglelderggivvdeflrt.n.vpgiyaiGDva. 278
                  + +  lek+Gv+++l++sv ++++ ++   k+  v+l+dg++++ad v++++Gv+p t++l ++  + l ++g i +de+ +  +   ++yaiGD+a 
   EEA18769.1 316 IFQGLLEKSGVKFYLNASVDKATPSSSspdKVGaVHLKDGTTLPADVVILGIGVKPATDFLANNPAISLLQDGSIRTDETFAIpSlNGDVYAIGDIAt 413
                  **************************99876669**************************9988888899***********8644699********** PP

                  ............TECCSS--HHHHHHHH CS
                  ............xxxxxxxxxxxxxxxx RF
  Pyr_redox_2 279 ............ggkggpelaqaAvqqG 294
                              g   ++e++ +A+++G
   EEA18769.1 414 ytyhgpgaapetGSPVRIEHWNVAQNAG 441
                  9999999999999999999999999887 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0      0.06        76       1      34 [.     132     167 ..     132     213 .. 0.77
   2 !   49.8   0.1     3e-16   3.9e-13       1      80 [.     272     354 ..     272     355 .. 0.90

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.06
                 EEEEECSSHHHHHHHHHHHHTT..SEEEEEESSSSS CS
   Pyr_redox   1 kvvvvGgGyiglElAgalaelg..kkVtvversdkl 34 
                 kvvv+GgG   + + ++l+el+   ++ ++  +++l
  EEA18769.1 132 KVVVIGGGSGSIGAVQTLRELNfkGSIALITKEPNL 167
                 79******9999999999887643455666655555 PP

  == domain 2  score: 49.8 bits;  conditional E-value: 3e-16
                 EEEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSS.TTSSHHHHHHHHHHHHHTTEEEECSEEEEEEE...EETTSEEEEEEET CS
   Pyr_redox   1 kvvvvGgGyiglElAgalaelgkkVtvversdkll.rllDeeaskilqeklekngievllntkveeie...gsedgvesvklkd 80 
                 kvv++G+++ig+E+++al++ +++V++v +++ +l r+++e+++ki+q  lek g++++ln++v + +    s+d+v +v+lkd
  EEA18769.1 272 KVVIIGSSFIGMEVGNALSK-NHDVSIVGMEKAPLeRVMGEKVGKIFQGLLEKSGVKFYLNASVDKATpssSSPDKVGAVHLKD 354
                 79****************98.559*******************************************96655556677777765 PP

>> Rieske  Rieske [2Fe-2S] domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.5   0.0   2.7e-17   3.5e-14       9      88 ..      14      96 ..       6      97 .. 0.84
   2 ?   -3.3   0.0         7   8.9e+03      23      41 ..     393     410 ..     387     411 .. 0.78

  Alignments for each domain:
  == domain 1  score: 52.5 bits;  conditional E-value: 2.7e-17
                GGC-TTCEEEEEETTEE...EEEEE-TTS-EEEEESC-TTTT-BCGGSEEETT.EEE-TTT--EEE.TTSBEEE-TTHHHEEEE CS
      Rieske  9 sdvpegdpltvkvggep...lvvlrdedgevyAlsdvCtHrgaplsegkidekgvleCpcHgwayd.adGkvikgPaprplaty 88
                +d+p+ + ++ +v g p   ++v+r  d++++A+s +CtH gapl+ g +  +g+++Cp+Hg++++ a+G++ ++Pa ++l t+
  EEA18769.1 14 QDIPNCEKVESEVEGVPggkVLVVRL-DDKFHAISPRCTHYGAPLKLGVVAPDGRITCPWHGACFTvATGEIEDAPALNRLGTF 96
                56666666666666655555999996.******************99***9999***********************9998776 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 7
                 TEEEEEEE-TTS-EEEEES CS
      Rieske  23 geplvvlrdedgevyAlsd 41 
                 +e+++++   +g+vyA+ d
  EEA18769.1 393 DETFAIPSL-NGDVYAIGD 410
                 677888885.999999876 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0   1.3e-06    0.0017     133     274 ..      97     241 ..      75     254 .. 0.76
   2 !   12.0   0.0   7.2e-05     0.092     163     291 ..     269     394 ..     257     409 .. 0.75

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 1.3e-06
  Pyr_redox_3 133 GefdkPnklnipGeeklvkhyskvkefhkya..gqkvvViGgknSavDaAlelvrk..gaeVtvvtrgseiekeesdpsyslkpd...ienrleelvk 223
                  G ++k     i+Gee   k  + +++++ +   ++kvvViGg+  ++ a   l +     ++ ++t++ ++  ++++ s  l +d   ie r +e ++
   EEA18769.1  97 GVYEKEGAVYIKGEEGSIKAGQRDPNLKCFVstDEKVVVIGGGSGSIGAVQTLRELnfKGSIALITKEPNLPLDRTKLSKALIADaskIELRPAEWYS 194
                  8888888899999995444444445554442339*********999888777766644678*********9999999999987762113445566666 PP

  Pyr_redox_3 224 eekikvlfnaevkeikekeeeykvktedgkkvevkddvvlatGykpdlsfl 274
                  +  i+v+ + ev++++ ++++  v+t++gk++ ++++ vlatG  p   +l
   EEA18769.1 195 NAGIDVVHD-EVTSVDFQTKS--VSTKSGKSF-SYTKLVLATGGIPRNLPL 241
                  666998887.99999998665..889998885.6899******98876555 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 7.2e-05
  Pyr_redox_3 163 agqkvvViGgknSavDaAlelvrkgaeVtvvtrgseiekeesdpsyslkpdienrleelvkeekikvlfnaevkeikekeeey....kvktedgkkve 256
                  +++kvv+iG +  ++++   l ++ ++V++v  ++   ++       +   + + ++ l++++ +k++ na+v++ + ++++      v+ +dg+++ 
   EEA18769.1 269 EKKKVVIIGSSFIGMEVGNALSKN-HDVSIVGMEKAPLER------VMGEKVGKIFQGLLEKSGVKFYLNASVDKATPSSSSPdkvgAVHLKDGTTLP 359
                  5789999**999999998777665.999999888743333......33445555666666666699999999999986544322113899***98877 PP

  Pyr_redox_3 257 vkddvvlatGykpdlsflkk.slfeldedgrpvlte 291
                  + d v+l +G kp ++fl++ + ++l +dg +  +e
   EEA18769.1 360 A-DVVILGIGVKPATDFLANnPAISLLQDGSIRTDE 394
                  5.777888***********98888887888776665 PP

>> Rieske_2  Rieske-like [2Fe-2S] domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.0   1.3e-08   1.7e-05       4     104 .]       9     108 ..       6     108 .. 0.89
   2 ?   -1.5   0.0       1.8   2.3e+03      33      46 ..     402     415 ..     381     419 .. 0.76

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 1.3e-08
                 EEEECCCS-TTB-EEEEET...TEEEEEEE-TTS-EEEEESS-TTTSSSTCCCSEEEECTTCEEEE-TTT--EEETTT-BBSS-TT.SB-BEE-EEEST CS
    Rieske_2   4 pvckledlvketgvaalvd...gkqvalfrlekeevyAidnldpaseanvlsrGlvgdkkgelvvasPlykqkfdLktGecledee.vslkvypvrved 98 
                 ++ +l+d+++ ++v + v+   g +v+++rl +++ +Ai+ +++  + ++l  G+v+ +     +++P ++  f  +tGe+ ++++  +l ++ v  ++
  EEA18769.1   9 DISSLQDIPNCEKVESEVEgvpGGKVLVVRL-DDKFHAISPRCTH-YGAPLKLGVVAPD---GRITCPWHGACFTVATGEIEDAPAlNRLGTFGVYEKE 102
                 5778999999999888876344789******.9************.799*******999...88*******************888589********** PP

                 SEEEEE CS
    Rieske_2  99 gkvevr 104
                 g+v+++
  EEA18769.1 103 GAVYIK 108
                 ***985 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1.8
                 TS-EEEEESS-TTT CS
    Rieske_2  33 keevyAidnldpas 46 
                 +++vyAi+++ + +
  EEA18769.1 402 NGDVYAIGDIATYT 415
                 67899999987765 PP

>> Reductase_C  Reductase C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.7   0.0   4.3e-08   5.4e-05       8      74 ..     471     540 ..     465     548 .. 0.86

  Alignments for each domain:
  == domain 1  score: 23.7 bits;  conditional E-value: 4.3e-08
                  TEEEEEEE-...-TT--EEEEEEETTTTEEEEEEEETTEEEEEEEES-HHHHHHHHHHTTTT----HHHH CS
  Reductase_C   8 dlklQiaGl...atgadevvvRgdpeerafsvfylrdgrlvaveavnrprdlmaarrliaagasvdpaal 74 
                  + +l+++G    ++g d ++++g+pe+++f+++y +++++vav++++    ++ a +l+ +g  +++a++
   EEA18769.1 471 GQQLRYCGNtmaSNGFDSLIIKGEPENAKFVAYYAKGDTIVAVATMGMDPIMVKAAELMRRGNMPKRAEI 540
                  5577777864446889***********************************************9999876 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.1       7.1   9.1e+03       1      19 [.     134     152 ..     134     167 .. 0.71
   2 !    8.5   0.0    0.0014       1.8     114     154 ..     195     233 ..     188     235 .. 0.89
   3 !   10.1   0.0   0.00047       0.6      95     154 ..     308     368 ..     287     370 .. 0.86

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 7.1
  NAD_binding_9   1 aivGaGprGlavlerLlar 19 
                    +++G+G   + +++ L + 
     EEA18769.1 134 VVIGGGSGSIGAVQTLREL 152
                    6899999888888777665 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0014
  NAD_binding_9 114 gvtvevhraevvdleeradgqavlladgaslaadaVvLAlG 154
                    +  ++v+++ev++++ + ++  v +++g+s+ + ++vLA+G
     EEA18769.1 195 NAGIDVVHDEVTSVDFQTKS--VSTKSGKSFSYTKLVLATG 233
                    45799***********9987..789***************9 PP

  == domain 3  score: 10.1 bits;  conditional E-value: 0.00047
  NAD_binding_9  95 lyGrYlrdlfeellarlpegvtvevhraevvdleeradgq.avlladgaslaadaVvLAlG 154
                    ++G+ + ++f+ ll++   ++ ++   ++++  + ++d++ av+l+dg++l ad V+L +G
     EEA18769.1 308 VMGEKVGKIFQGLLEKSGVKFYLNASVDKATPSSSSPDKVgAVHLKDGTTLPADVVILGIG 368
                    666667778888888888888888899999999999999889****************998 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.6   0.0    0.0058       7.4     190     240 ..     129     178 ..     115     187 .. 0.87
   2 !    7.5   0.0    0.0016         2     133     215 ..     208     294 ..     193     305 .. 0.67
   3 ?   -2.8   0.0         2   2.6e+03     119     160 ..     334     371 ..     327     373 .. 0.64

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0058
  K_oxygenase 190 akkriaVvGsGqSaaeifedllrrqkkvelklvtrsealeplddspfvnei 240
                  + ++++V+G+G      ++ l + + k +++l+t++++l pld +++ + +
   EEA18769.1 129 TDEKVVVIGGGSGSIGAVQTLRELNFKGSIALITKEPNL-PLDRTKLSKAL 178
                  6789*******9999999999999999*********997.99999997765 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0016
  K_oxygenase 133 ltveskd.aegeeeelearnlvlgvGtep.kiP.evleklegkervvHsseylerkee.llakkriaVvGsGqSaaeifedllrrqk 215
                  ++ ++k+ ++ + ++++  +lvl++G+ p ++P e +++l +  ++    ++ +  ++  ++kk+++++Gs   + e+ + l ++ +
   EEA18769.1 208 VDFQTKSvSTKSGKSFSYTKLVLATGGIPrNLPlEGFKDLGNIFKLRFVTDVQSILRAlGEEKKKVVIIGSSFIGMEVGNALSKNHD 294
                  3444444466778899999*******7663799555888775333333333333222248999********9999999988877654 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 2
  K_oxygenase 119 veevepdeeeeeelltveskdaegeeeelearnlvlgvGtep 160
                  v++ +p++++ +++  v+      + ++l a  ++lg+G +p
   EEA18769.1 334 VDKATPSSSSPDKVGAVHL----KDGTTLPADVVILGIGVKP 371
                  5555555555445555555....2457888888999999888 PP

>> Kelch_1  Kelch motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.1   0.00046      0.59       6      22 ..     125     141 ..     122     153 .. 0.83
   2 ?    2.0   0.0      0.12   1.5e+02       6      18 ..     397     409 ..     395     409 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00046
                 EEEEETTEEEEEEEBCS CS
     Kelch_1   6 gavvvggkiYviGGsdg 22 
                 ++v+ ++k+ viGG++g
  EEA18769.1 125 CFVSTDEKVVVIGGGSG 141
                 789************99 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.12
                 EEEEETTEEEEEE CS
     Kelch_1   6 gavvvggkiYviG 18 
                 +  +++g +Y+iG
  EEA18769.1 397 AIPSLNGDVYAIG 409
                 67789*******9 PP

>> DUF1188  Protein of unknown function (DUF1188)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.1   3.2e-05     0.041      33      75 ..     260     302 ..     247     333 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 3.2e-05
                 HHHHTT--E..EEEEEES-CCCHHHHHHHHCCCEEEEEEESSG CS
     DUF1188  33 leyleeeeleeknvlviGaYltGaaiakkLskkeevtlvDiep 75 
                 ++ l     e+k+v++iG+ + G+ + ++Lsk+++v +v +e+
  EEA18769.1 260 QSILRALGEEKKKVVIIGSSFIGMEVGNALSKNHDVSIVGMEK 302
                 555555666789**************************98875 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.1      0.37   4.7e+02       2      19 ..     132     148 ..     131     166 .. 0.73
   2 ?    5.1   0.0    0.0061       7.8     130     164 ..     203     234 ..     190     240 .. 0.80
   3 ?    3.9   0.0     0.014        18     111     166 ..     313     371 ..     307     396 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.37
                  SEEEE--SHHHHHHHHHH CS
  HI0933_like   2 dviviGgGaAGlmaAisa 19 
                  +v+viGgG +G  +A++ 
   EEA18769.1 132 KVVVIGGG-SGSIGAVQT 148
                  79****99.566666665 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0061
                  --EEEEECETTE.EEEEE.TTEEEEESEEEE---- CS
  HI0933_like 130 tevksvekeedgkfrvktkseeeleadklvlAtGG 164
                   ev+sv+    ++ +v+tks+++++ +klvlAtGG
   EEA18769.1 203 DEVTSVDF---QTKSVSTKSGKSFSYTKLVLATGG 234
                  45666644...44569999***************9 PP

  == domain 3  score: 3.9 bits;  conditional E-value: 0.014
                  HHHHHHHHHHHHT-EEE-S--EEEE...ECETTE.EEEEE.TTEEEEESEEEE----SS CS
  HI0933_like 111 ivdallkelkeagvklrletevksv...ekeedgkfrvktkseeeleadklvlAtGGlS 166
                  + ++++  l+++gvk++l+ +v ++   +++ d++  v++k++++l ad ++l +G + 
   EEA18769.1 313 VGKIFQGLLEKSGVKFYLNASVDKAtpsSSSPDKVGAVHLKDGTTLPADVVILGIGVKP 371
                  5567777899**************9666677888899999*************999765 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.1      0.51   6.6e+02       1      17 [.     132     148 ..     132     166 .. 0.68
   2 ?    8.3   0.0   0.00084       1.1     108     150 ..     195     234 ..     174     247 .. 0.90
   3 ?    0.4   0.0       0.2   2.6e+02     126     162 ..     345     386 ..     323     462 .. 0.81

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.51
                 CEEEE-SSHHHHHHHHH CS
        GIDA   1 dviViGgGhAGceAAla 17 
                 +v+ViGgG   + A  +
  EEA18769.1 132 KVVVIGGGSGSIGAVQT 148
                 69******754444444 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.00084
                 STTEEEEES-EEEEEECTTEEEEEEETTS-EEEECEEEE--TT CS
        GIDA 108 epnleiieeeveeliveekkvkgvvtedgetikakavviatGt 150
                 +  ++++++ev++++    ++k v t++g+ ++  + v+atG 
  EEA18769.1 195 NAGIDVVHDEVTSVDF---QTKSVSTKSGKSFSYTKLVLATGG 234
                 46799*********99...99*********************6 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.2
                 TEEEEEEETTS-EEEECEEEE--TT.....-BT-EEEETTEE CS
        GIDA 126 kkvkgvvtedgetikakavviatGt.....flkgkihigeke 162
                 +kv +v ++dg+t+ a++v++  G      fl+ ++ i   +
  EEA18769.1 345 DKVGAVHLKDGTTLPADVVILGIGVkpatdFLANNPAISLLQ 386
                 88999****************999866777777766665554 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.18   2.2e+02       1      51 [.     133     184 ..     133     210 .. 0.78
   2 ?    8.8   0.1    0.0015       1.9       1      41 [.     273     312 ..     273     328 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.18
                 EEEES-SHHHHHHHHHHHH.TT..EEEEEEESSHHHHHHHHHTTSEEEES-TTS CS
      TrkA_N   1 iiiiGlGrvGrslaeeLse.gg..kdvvvidkdeerveelreeglevvvgdatd 51 
                 +++iG G      +++L+e +   + + +i k+++     r +  +++++da++
  EEA18769.1 133 VVVIGGGSGSIGAVQTLRElNFkgS-IALITKEPNL-PLDRTKLSKALIADASK 184
                 6999999999999999999554644.8888887754.33345666777777765 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0015
                 EEEES-SHHHHHHHHHHHHTTEEEEEEESSHHHHHHHHHTT CS
      TrkA_N   1 iiiiGlGrvGrslaeeLseggkdvvvidkdeerveelreeg 41 
                 ++iiG + +G+++ + Ls+++ dv+++  +++ +e++  e+
  EEA18769.1 273 VVIIGSSFIGMEVGNALSKNH-DVSIVGMEKAPLERVMGEK 312
                 79*****************99.6999988888888887655 PP

>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00016      0.21     216     262 ..     320     369 ..     293     386 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00016
                    HHHTTTTEEEETSEEEEEEEE...ETTC.EEEEETTSTEEEESEEEE-S-H CS
  Amino_oxidase 216 laeelrgldirlntrVkeikr...egdg.vtvtledgevveaDaVvvTvpl 262
                    l e ++g+++ ln+ V + +    ++d+  +v+l+dg++++aD V++ + +
     EEA18769.1 320 LLE-KSGVKFYLNASVDKATPsssSPDKvGAVHLKDGTTLPADVVILGIGV 369
                    445.89***************9998888789***************98876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (557 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       346  (0.0192983); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.73u 0.35s 00:00:01.08 Elapsed: 00:00:00.55
# Mc/sec: 3037.21
//
Query:       EEA18770.1  [L=870]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
      0.012   15.5   4.6      0.012   15.5   4.6    3.1  4  Phage_GP20     Phage minor structural protein GP20
      0.088   12.8   2.3       0.73    9.9   0.1    3.0  2  Bap31_Bap29_C  Bap31/Bap29 cytoplasmic coiled-coil domain
        4.1    7.5   6.3         16    5.6   0.0    2.8  2  DUF1639        Protein of unknown function (DUF1639)


Domain annotation for each model (and alignments):
>> Phage_GP20  Phage minor structural protein GP20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   4.5     0.083     5e+02      34     126 ..      91     188 ..      89     193 .. 0.78
   2 ?    2.2   4.2     0.024   1.5e+02      17      65 ..     169     217 ..     145     224 .. 0.80
   3 ?   15.5   4.6   1.9e-06     0.012      18     106 ..     208     301 ..     193     307 .. 0.86
   4 ?   -1.8   0.1      0.41   2.4e+03     101     124 ..     326     349 ..     316     353 .. 0.49

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.083
  Phage_GP20  34 lkdrdkqLedLkkkakdneeLqkq.ieelqaknkkakaeyeakiadlkldnaielaLkeakaknekavkalld....kdklklkedgelkgLdeqikk 126
                 l+ ++  L dL+k+ ++++ L ++ ++ +++ + +a+a+    + +++  +  +++ + a+a+  +  + ll+    ++++ ++ d e+k L+e +++
  EEA18770.1  91 LEHNNVALGDLEKDLETAARLGQAlLQRHETYVSEAEADRSRLLLEMERLERDKQEVQSANARIVEENRRLLEqlegLNNAVATSDNEVKALSERLQQ 188
                 66778889999999999999965516778888999999999999999999999999999999876666666665555677777788888888888775 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.024
  Phage_GP20  17 kakldeveeerdtlkeqlkdrdkqLedLkkkakdneeLqkqieelqakn 65 
                 ++++++ ++e++ l e+l++ + ++ +L ++a  +++L+ q+++++a+ 
  EEA18770.1 169 NNAVATSDNEVKALSERLQQTQLEMRELAASAVRAADLEIQLNTMEAEQ 217
                 6677888999999999999999999999999999999999999999875 PP

  == domain 3  score: 15.5 bits;  conditional E-value: 1.9e-06
  Phage_GP20  18 akldeveeerdtlkeql....kdrdkqLedLkkkakdneeLqkqieelqaknkkakaeyeakiadlkldnaielaLkeakakne.kavkalldk 106
                  +l+++e+e+ +l++ql    +d  + ++  kk+  +  +Lq q++ l+ ++  + +e+ + i+ ++   a+e +L++a  + + +a  a +d+
  EEA18770.1 208 IQLNTMEAEQMELQQQLilthEDEKSAVQRWKKAETTLHDLQDQLDRLEYEATMEREEHSKIIERMERRRAVERELDGAAGRLKgAAASAVMDR 301
                 57899999*******987776788889***************************************************9887542566777776 PP

  == domain 4  score: -1.8 bits;  conditional E-value: 0.41
  Phage_GP20 101 kalldkdklklkedgelkgLdeqi 124
                 +++ ++ +l  + + e++ L eqi
  EEA18770.1 326 MGIVELRELLESSNQEVENLREQI 349
                 444444444444444444444444 PP

>> Bap31_Bap29_C  Bap31/Bap29 cytoplasmic coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.5     0.074   4.4e+02       1      16 [.     177     192 ..     163     199 .. 0.65
   2 ?    9.9   0.1   0.00012      0.73       3      24 ..     328     349 ..     327     353 .. 0.92

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.074
  Bap31_Bap29_C   1 keiekLkkeLkkkkkD 16 
                    +e+++L + L++++++
     EEA18770.1 177 NEVKALSERLQQTQLE 192
                    4666666666666655 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.00012
  Bap31_Bap29_C   3 iekLkkeLkkkkkDlealKkQa 24 
                    i +L++ L+++++++e+l++Q+
     EEA18770.1 328 IVELRELLESSNQEVENLREQI 349
                    679******************7 PP

>> DUF1639  Protein of unknown function (DUF1639)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   4.4     0.097   5.8e+02      16      26 ..     405     415 ..     402     420 .. 0.85
   2 ?    5.6   0.0    0.0027        16      18      48 ..     651     681 ..     649     682 .. 0.95

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.097
     DUF1639  16 kkpprRPKKRp 26 
                 k+p rRPKKR 
  EEA18770.1 405 KQPIRRPKKRR 415
                 5799*****96 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0027
     DUF1639  18 pprRPKKRpknVqkqldslfPGlwLsevtad 48 
                 +prRP  R  +V +++ s  P  + +++tad
  EEA18770.1 651 LPRRPPQRVVTVATEISSTPPVISTTNITAD 681
                 69***************************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (870 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1595  (0.088962); expected 358.6 (0.02)
Passed bias filter:                      413  (0.0230353); expected 358.6 (0.02)
Passed Vit filter:                        71  (0.00396006); expected 17.9 (0.001)
Passed Fwd filter:                        29  (0.00161749); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 1.17u 0.37s 00:00:01.54 Elapsed: 00:00:00.58
# Mc/sec: 4539.63
//
Query:       EEA18771.1  [L=731]
Description: Ran-binding protein (RanBP10), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.6e-29  101.2   0.0    9.4e-29  100.2   0.0    1.5  1  CLTH      CTLH/CRA C-terminal to LisH motif domain
    1.2e-20   73.9   0.1      2e-20   73.1   0.1    1.4  1  SPRY      SPRY domain
    0.00015   21.6   0.3     0.0005   19.9   0.3    2.0  1  LisH      LisH


Domain annotation for each model (and alignments):
>> CLTH  CTLH/CRA C-terminal to LisH motif domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.2   0.0   1.6e-32   9.4e-29       3     147 ..     521     713 ..     519     714 .. 0.84

  Alignments for each domain:
  == domain 1  score: 100.2 bits;  conditional E-value: 1.6e-32
        CLTH   3 kerqkIiklilegdlseaiewinenkpellesnsnLeFkLkllqfielirg........kt...................................... 55 
                 ++rqkI+ +ilegd++ a++++n ++p++l+ n++++FkL++++f+e++ +        +t                                      
  EEA18771.1 521 ANRQKIRAAILEGDMDRALKYTNAYFPKVLQDNPHILFKLRCRKFLEMMCKcsdsssaaTTervkdsgeemevddgysdgegmeteesaptttaddsak 619
                 79************************************************8877766661155666666677777777777777788888888877766 PP

        CLTH  56 ..kdieealeyare.nle...fend..ehlkelekamsLLafsdpeskelssplknlldpsrrekvakefnsailkllglskespLeillsaglsalkt 146
                   + ++ea++y+++ ++       +    ++ l +++sL a++dp s    s +++ ld s r+ va+ +n+ail +lg+s+ ++Le ++s++  ++++
  EEA18771.1 620 fhDLLTEAVQYGQQlRMDypsD--EygGDKQYLDDIFSLVAYPDPRS----SVHGHHLDASGRVAVADDLNAAILVSLGKSSTAALETIYSQTEALVNE 712
                 6555**********74432223..24589***************998....79***************************************9888876 PP

        CLTH 147 l 147
                 l
  EEA18771.1 713 L 713
                 5 PP

>> SPRY  SPRY domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.1   0.1   3.3e-24     2e-20       1     119 [.     306     430 ..     306     431 .. 0.95

  Alignments for each domain:
  == domain 1  score: 73.1 bits;  conditional E-value: 3.3e-24
                 EEEEEEEET.CCTSSEEEEEEEETTSSSSSTSSSTSSTTEEEEETETTEEE...EETESCEEEESSSSTTSEEEEEEETTTTEEEEEETTEEEEEEEES CS
        SPRY   1 khyfevkiq.saeggsisvGlateqtdlsdksgegddrgswglcgdngtrt...saeqskaygkqparegdviGvalDleegelsFtkngknlgvaFrn 95 
                 ++y+e +i+ + ++  i +G++  +++   ++  g+d++sw+++gd+g+ +   ++ q+ + g+ +++ +d+iG+++++ +++ +Ftkng+  g+aF++
  EEA18771.1 306 IYYYEATILvKPKDAVIAIGFSSPRAS--LERLPGWDNESWAYHGDDGKAFigeNQGQGRPFGP-TFTVNDTIGCGVNFTTRSTFFTKNGILIGTAFKD 401
                 59*************************..666779******************99999999999.********************************** PP

                 TTTS...SEEEEEEE...STCEEEEESSE CS
        SPRY  96 vrga...elfPvvslg..ngaslkinlgl 119
                 ++ +    ++P + ++  ng  +++n+g+
  EEA18771.1 402 LPASksiSFYPSIGMKrhNGMHVRVNFGQ 430
                 ***9999*********9999999***997 PP

>> LisH  LisH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   0.3   8.3e-08    0.0005       2      26 ..     469     493 ..     468     494 .. 0.94

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 8.3e-08
                 HHHHHHHHHHHHCT-HHHHHHHHHH CS
        LisH   2 eLNrLIydYLvkeGyeetAeaFekE 26 
                 +L  L+  +L  eGy etA++F++E
  EEA18771.1 469 LLQELVAQFLAQEGYYETARTFAEE 493
                 6889*******************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (731 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       666  (0.0371465); expected 358.6 (0.02)
Passed bias filter:                      400  (0.0223102); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.83u 0.33s 00:00:01.15 Elapsed: 00:00:00.56
# Mc/sec: 3920.71
//
Query:       EEA18772.1  [L=723]
Description: Ran-binding protein (RanBP10), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.5e-25   87.6   0.0    1.6e-24   86.5   0.0    1.6  1  CLTH      CTLH/CRA C-terminal to LisH motif domain
    1.1e-20   73.9   0.1    1.9e-20   73.1   0.1    1.4  1  SPRY      SPRY domain
    0.00032   20.5   1.4    0.00049   20.0   0.3    2.0  2  LisH      LisH


Domain annotation for each model (and alignments):
>> CLTH  CTLH/CRA C-terminal to LisH motif domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.5   0.0   2.7e-28   1.6e-24       3     125 ..     521     691 ..     519     710 .. 0.83

  Alignments for each domain:
  == domain 1  score: 86.5 bits;  conditional E-value: 2.7e-28
        CLTH   3 kerqkIiklilegdlseaiewinenkpellesnsnLeFkLkllqfielirg........kt...................................... 55 
                 ++rqkI+ +ilegd++ a++++n ++p++l+ n++++FkL++++f+e++ +        +t                                      
  EEA18772.1 521 ANRQKIRAAILEGDMDRALKYTNAYFPKVLQDNPHILFKLRCRKFLEMMCKcsdsssaaTTervkdsgeemevddgysdgegmeteesaptttaddsak 619
                 79************************************************8877766661155666666677777777777777788888888877766 PP

        CLTH  56 ..kdieealeyare.nle...fend..ehlkelekamsLLafsdpeskelssplknlldpsrrekvakefnsailkll 125
                   + ++ea++y+++ ++       +    ++ l +++sL a++dp s    s +++ ld s r+ va+ +n+ail +l
  EEA18772.1 620 fhDLLTEAVQYGQQlRMDypsD--EygGDKQYLDDIFSLVAYPDPRS----SVHGHHLDASGRVAVADDLNAAILGML 691
                 6555**********74432223..24589***************998....79**********************887 PP

>> SPRY  SPRY domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.1   0.1   3.3e-24   1.9e-20       1     119 [.     306     430 ..     306     431 .. 0.95

  Alignments for each domain:
  == domain 1  score: 73.1 bits;  conditional E-value: 3.3e-24
                 EEEEEEEET.CCTSSEEEEEEEETTSSSSSTSSSTSSTTEEEEETETTEEE...EETESCEEEESSSSTTSEEEEEEETTTTEEEEEETTEEEEEEEES CS
        SPRY   1 khyfevkiq.saeggsisvGlateqtdlsdksgegddrgswglcgdngtrt...saeqskaygkqparegdviGvalDleegelsFtkngknlgvaFrn 95 
                 ++y+e +i+ + ++  i +G++  +++   ++  g+d++sw+++gd+g+ +   ++ q+ + g+ +++ +d+iG+++++ +++ +Ftkng+  g+aF++
  EEA18772.1 306 IYYYEATILvKPKDAVIAIGFSSPRAS--LERLPGWDNESWAYHGDDGKAFigeNQGQGRPFGP-TFTVNDTIGCGVNFTTRSTFFTKNGILIGTAFKD 401
                 59*************************..666779******************99999999999.********************************** PP

                 TTTS...SEEEEEEE...STCEEEEESSE CS
        SPRY  96 vrga...elfPvvslg..ngaslkinlgl 119
                 ++ +    ++P + ++  ng  +++n+g+
  EEA18772.1 402 LPASksiSFYPSIGMKrhNGMHVRVNFGQ 430
                 ***9999*********9999999***997 PP

>> LisH  LisH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   0.3   8.2e-08   0.00049       2      26 ..     469     493 ..     468     494 .. 0.94
   2 ?   -3.4   0.0       1.9   1.1e+04       1       8 [.     681     688 ..     681     688 .. 0.85

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 8.2e-08
                 HHHHHHHHHHHHCT-HHHHHHHHHH CS
        LisH   2 eLNrLIydYLvkeGyeetAeaFekE 26 
                 +L  L+  +L  eGy etA++F++E
  EEA18772.1 469 LLQELVAQFLAQEGYYETARTFAEE 493
                 6889*******************99 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 1.9
                 HHHHHHHH CS
        LisH   1 eeLNrLIy 8  
                 ++LN+ I+
  EEA18772.1 681 DDLNAAIL 688
                 69***996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (723 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       644  (0.0359195); expected 358.6 (0.02)
Passed bias filter:                      384  (0.0214178); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.79u 0.38s 00:00:01.17 Elapsed: 00:00:00.58
# Mc/sec: 3737.97
//
Query:       EEA18773.1  [L=364]
Description: alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.7e-18   64.6   0.0    1.3e-17   64.0   0.0    1.2  1  ADH_zinc_N    Zinc-binding dehydrogenase
    3.1e-10   39.9   0.0    8.6e-10   38.5   0.0    1.7  1  ADH_N_2       N-terminal domain of oxidoreductase
    1.4e-07   32.7   0.0    2.4e-07   31.8   0.0    1.5  1  ADH_zinc_N_2  Zinc-binding dehydrogenase
  ------ inclusion threshold ------
       0.12   12.6   0.0         13    6.0   0.0    2.3  2  DUF2534       Protein of unknown function (DUF2534)


Domain annotation for each model (and alignments):
>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.0   0.0     3e-21   1.3e-17       1     116 [.     180     303 ..     180     322 .. 0.88

  Alignments for each domain:
  == domain 1  score: 64.0 bits;  conditional E-value: 3e-21
                 HHHHHHHHHHHHTT-EEEEEESSHHHHHH.HHHTTESEEEETTTC.HHHHHHHHHTTTSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSC..TSSEE CS
  ADH_zinc_N   1 gvGlaavqlAkalGaeviavdsseeklel.akklGadevinykea.dlverikeltggegvdvvfecvGsgatleaalkllkpgGrlvvvGg..gkgee 95 
                 +vG+++ q+Ak  G +vi+ ++++ kl++ + +lG d  +nyk++ ++ e+++++  ++gvd+++e vG g+ l aal++l+  Gr+   G+       
  EEA18773.1 180 AVGQIVGQIAKKEGLKVIGSVGDDAKLDFiVNELGFDSGFNYKKEtSVLEALQRHA-PNGVDIYYENVG-GEHLAAALECLNVFGRIIASGMvsQ-YSL 275
                 69*************************972566*********9999**********.9***********.**********************852.333 PP

                 E.......EEHHHHHHTT-EEEEE-SSC CS
  ADH_zinc_N  96 e.......fdlrnlllkeksilGsllgs 116
                 +        +l +++ k+++++G+l+ +
  EEA18773.1 276 PpddrypiKNLTQIIPKRIRFQGFLVND 303
                 357886666666699*********9987 PP

>> ADH_N_2  N-terminal domain of oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.5   0.0   1.9e-13   8.6e-10      27      78 ..      36      89 ..      25     128 .. 0.74

  Alignments for each domain:
  == domain 1  score: 38.5 bits;  conditional E-value: 1.9e-13
     ADH_N_2 27 elkdGevlvralylSvDPymRgrmnd..aksyvepvelgdvmrggavgeVveSk 78
                ++ +G ++++ ly+S DPymRgrm+   + sy++p+e+g+++++ a+ +V+  +
  EEA18773.1 36 HVPEGSAIIKGLYFSCDPYMRGRMRPptKSSYAPPFEIGKPIAAYALVQVLRLE 89
                56799********************543789999*************9998533 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.8   0.0   5.5e-11   2.4e-07       1     133 []     213     358 ..     213     358 .. 0.73

  Alignments for each domain:
  == domain 1  score: 31.8 bits;  conditional E-value: 5.5e-11
                   TT-SEEEETTSTTHH....HHH-TT-EEEEEES-HHHHH.HHHHHHEEEEEEEEE----...............S-EEE-CHHHCTTT-EEEE--GG CS
  ADH_zinc_N_2   1 lGAdevidyrtedfe....aatggegvDvvldtvggealleaslkvlpggGrlvsiggpp..............lsaallkpakkrkgrsvkyeflf 79 
                   lG+d  ++y++e  +    +   ++gvD+ +++vgge+l +a+l++l+  Gr++  g+ +              l++ ++k+ ++++          
    EEA18773.1 213 LGFDSGFNYKKETSVlealQRHAPNGVDIYYENVGGEHL-AAALECLNVFGRIIASGMVSqyslppddrypiknLTQIIPKRIRFQGFLVN------ 302
                   7999999***55555589955568*************99.9999***999***98886445666666444433333333333333333333...... PP

                   G...-........-HHHHHHHHHHHHHHH----EEEEEEGGGHHHHHHHHHSS--SSEEEE CS
  ADH_zinc_N_2  80 smkas.......aqadileelaalieeGklrpvvdrvfpleeaaeAhrylesgrarGKiVl 133
                       +       + +++ e++ ++++eG +++      ++++a +A+  + +g+ +GK ++
    EEA18773.1 303 ----DpdfgpkyV-KERDERVPQWLAEGSIKTKEHIDEGIDQAGTAFVNMLAGKNFGKAII 358
                   ....134566642.33359************9777668********************986 PP

>> DUF2534  Protein of unknown function (DUF2534)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.0     0.012        52      30      51 ..     130     151 ..     112     163 .. 0.79
   2 ?    6.0   0.0     0.003        13      22      41 ..     257     276 ..     250     281 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.012
     DUF2534  30 tigGvidqYnlPlseWttsmfl 51 
                  ++ v++ YnlPls++ ++m +
  EEA18773.1 130 YVNKVENPYNLPLSNFLSAMGM 151
                 567899**********999965 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.003
     DUF2534  22 alsvvsratigGvidqYnlP 41 
                  l v +r++  G+++qY lP
  EEA18773.1 257 CLNVFGRIIASGMVSQYSLP 276
                 6899***************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (364 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       266  (0.0148363); expected 358.6 (0.02)
Passed bias filter:                      261  (0.0145574); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 2542.75
//
Query:       EEA18774.1  [L=265]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    3.4e-53  181.1  18.6    3.4e-53  181.1  18.6    1.5  2  INO80_Ies4  INO80 complex subunit Ies4


Domain annotation for each model (and alignments):
>> INO80_Ies4  INO80 complex subunit Ies4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  181.1  18.6   1.9e-57   3.4e-53      21     242 .]       9     238 ..       3     238 .. 0.76
   2 ?    1.1   0.5     0.019   3.3e+02     224     242 .]     219     238 ..     206     264 .. 0.42

  Alignments for each domain:
  == domain 1  score: 181.1 bits;  conditional E-value: 1.9e-57
  INO80_Ies4  21 akkklivtlkvspekLrailed.....kekekkeekespasssaapaakaeskadnasdsnsatPaegtPapssaamgpptekggpkkkagvKRsaaaa 114
                 ++ ++ ++lk+s+ +L++++++     ++  k ++ +sp ss +  a  ++s+ d+asd++s      tPa+++ + ++++++g+ +++ g+KR+  ++
  EEA18774.1   9 TQPSRTIVLKLSSTLLSRFPHErpsvdEKDIKIKDASSPPSSISGEAGLQASSFDAASDAAS------TPAATTETGKAKKSNGAGGAR-GTKRALDKT 100
                 334469***************656665778888999999999999999999999*******9......999999777777776666666.******997 PP

  INO80_Ies4 115 adgepaakvRgkPG.PKKkarLeDGtideeaeraaaaahkLGPKAnqGaINAgLRALDRsGkPCRkWekkglqlksFTGvvweiprWrappkkkp.... 208
                   g++ + +R++P   KK+ +L+D t+d++  + + ++hkLGPKAnqGaINAgLRALDRsG+PCRkWe+k++qlksFTGvvw +++W++p+   +    
  EEA18774.1 101 --GDAPKPARSRPSaAKKRLKLDDKTTDSS--KLVPPGHKLGPKANQGAINAGLRALDRSGAPCRKWERKSFQLKSFTGVVWGLSSWHTPKPLPQqqtp 195
                 ..6666779****7369999*******984..567889***************************************************9764431122 PP

  INO80_Ies4 209 .eeeeeesaa.......asaseegdsssken.ensqvkseksn 242
                  e++  e+ +       a+++ ++ds sk+n  +s+v+seksn
  EEA18774.1 196 gESSGAEEVNgvtpaavAAVNGDSDSVSKANlMSSAVPSEKSN 238
                 3222222111111111122233444556667666699999886 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.019
  INO80_Ies4 224 gdsssken.ensqvkseksn 242
                 +ds sk+n  +s+v+seksn
  EEA18774.1 219 SDSVSKANlMSSAVPSEKSN 238
                 23333333222233333332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (265 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      221  (0.0123264); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.29s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 1784.38
//
Query:       EEA18775.1  [L=364]
Description: membrane associated DnaJ chaperone, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-14   52.4   0.1    7.2e-14   51.7   0.1    1.4  1  DnaJ      DnaJ domain


Domain annotation for each model (and alignments):
>> DnaJ  DnaJ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.7   0.1     4e-18   7.2e-14       1      63 []      76     141 ..      76     141 .. 0.90

  Alignments for each domain:
  == domain 1  score: 51.7 bits;  conditional E-value: 4e-18
                 HHHHHHTSSTTG-HHHHHHHHHHHHHHHSTTTSCCHH...HHHHHHHHHHHHHHHHTSHHHHHHHH CS
        DnaJ   1 dyYeiLgvskdasedeIkkaYrklalkyHPDknpkdp...eaeekFkeineAyevLsdpekRkqYD 63 
                 d+Y++Lgvs+ a+e +Ik+++r+la ++HPDk ++++    ++  F  +++A ++L dp+ R +YD
  EEA18775.1  76 DFYSLLGVSPLADERTIKSRFRRLAAQHHPDKLNQQQqttLSDSFFVYLKQAQDTLLDPSVRFAYD 141
                 79*****************************774444355667799*******************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (364 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       601  (0.0335211); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.26s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2371.57
//
Query:       EEA18776.1  [L=441]
Description: RNA polymerase I subunit Rpa43, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.7e-41  139.3   0.1    9.7e-41  139.3   0.1    2.9  3  RPA43_OB         RPA43 OB domain in RNA Pol I
    0.00054   20.3   0.0     0.0016   18.8   0.0    1.9  2  SHS2_Rpb7-N      SHS2 domain found in N terminus of Rpb7p/Rpc
  ------ inclusion threshold ------
        1.2    7.2   6.3        1.8    6.6   6.3    1.1  1  FSA_C            Fragile site-associated protein C-terminus
        5.1    6.4  10.9       0.98    8.7   7.2    1.6  2  DUF4805          Domain of unknown function (DUF4805)


Domain annotation for each model (and alignments):
>> RPA43_OB  RPA43 OB domain in RNA Pol I
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.1      0.61   2.7e+03      64      75 ..      17      28 ..       4      74 .. 0.47
   2 !  139.3   0.1   2.2e-44   9.7e-41       1     124 []     170     340 ..     170     340 .. 0.89
   3 ?    1.3   3.7      0.12   5.2e+02      52      76 ..     406     430 ..     376     439 .. 0.38

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.61
                ------------ CS
    RPA43_OB 64 eeadaekeeeee 75
                +e +++k+++++
  EEA18776.1 17 KEHEPSKKRKNA 28
                111111111111 PP

  == domain 2  score: 139.3 bits;  conditional E-value: 2.2e-44
                 --TTEEEEEEEEEEESSEEEEEETTTEEEEEECTTS-TTSEEE.........CSS------.............---------..-------------- CS
    RPA43_OB   1 PqrgqkLeGwvnlqseghiglvvlnlFnvsIerkrlpadWkwvpae......kkkekgkka.............eeeeeeeee..eadaekeeeeelek 78 
                 Pq+gq+LeGw+n+qseg++g++v+nlF+v+Ierkrlp++Wkwvp++      +      +a             +e++++ ++  ++daeke++++l+k
  EEA18776.1 170 PQKGQVLEGWINVQSEGFVGAIVHNLFSVGIERKRLPKSWKWVPPGadedesN------TAsdkkkgyvsatsgDEDGSSGSNkvAFDAEKEHFTPLPK 262
                 9******************************************8885554431......333445667789999555555444449************9 PP

                 --...............................EEEEEEE-T.TSSB--SEEEEEEEEEE-......SSSS-EEEEES- CS
    RPA43_OB  79 ae...............................eetGywvdsvsgekvegklkFrvvdvdv..gserdkgflsieGtll 124
                 ++                               ++tGy+ +svsg++v+g+++Frv+dvdv  g++ d+gflsieGt+l
  EEA18776.1 263 KVsrqpinlldsdtnmlgeefgeyddeeddeasNATGYF-QSVSGHRVRGTIRFRVRDVDVipGADPDRGFLSIEGTML 340
                 99*************************************.999***********************************8 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.12
                 ----.....--------------------- CS
    RPA43_OB  52 gkka.....eeeeeeeeeeadaekeeeeel 76 
                 ++++     e     +++++++ek++++++
  EEA18776.1 406 TTTTaaaksE-----SKDDKKKEKKKSKDK 430
                 1111112211.....111111111111111 PP

>> SHS2_Rpb7-N  SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0       3.1   1.4e+04      38      50 ..      52      64 ..      52      65 .. 0.86
   2 !   18.8   0.0   3.5e-07    0.0016       2      70 .]      74     168 ..      73     168 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 3.1
                 EEEEEEEEEECCE CS
  SHS2_Rpb7-N 38 ivavldiaeyseg 50
                 +v+v+d a++++g
   EEA18776.1 52 VVSVTDAAKSDAG 64
                 799****999987 PP

  == domain 2  score: 18.8 bits;  conditional E-value: 3.5e-07
                  EEEEE-GGGTTS.THHHHHHHHHHHHHTTBEETTT.EEEEEEEEEEEECC........................EEE-TTTSSEEEEEEEEEEEE CS
  SHS2_Rpb7-N   2 dtvrlePsylgs.tledallerllekyegkvvpsl.Gvivavldiaeyse........................gkvlggsGsvyvrVtfralvF 70 
                  ++v+l P  ++s +  ++l +++l +++ +++p + G+++a+++   ++                              ++G+ y+ +t+++l+F
   EEA18776.1  74 MYVPLSPISISStHASASLIAEHLAPLLLTYYPPFqGIVLAYSNGSISESppvpgqvhssssqpdfdnpkpltlALTANEYGVLYLYLTATFLIF 168
                  69******************************************988777888888888888888888888886666788888888888888888 PP

>> FSA_C  Fragile site-associated protein C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   6.3   0.00039       1.8     546     609 ..     371     434 ..     345     439 .. 0.78

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.00039
       FSA_C 546 saakssleslqgsqdsiaiattasavelndatsstiasaatasslsstkstvtivvstndskdg 609
                 +a+++s+++ q sq ++a     ++++  ++t++t++++a+a s s  + + +   s + sk  
  EEA18776.1 371 AASSQSVSQSQNSQVNVAEVRLPETATPASTTTTTTTTTAAAKSESKDDKKKEKKKSKDKSKSK 434
                 4566678888999999999999999999999988888888888888877777777776666655 PP

>> DUF4805  Domain of unknown function (DUF4805)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.1       0.7   3.1e+03      60      69 ..      23      32 ..       8      93 .. 0.50
   2 ?    8.7   7.2   0.00022      0.98     145     194 ..     376     428 ..     355     438 .. 0.49

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 0.7
     DUF4805 60 drrkrsatss 69
                ++rk++at++
  EEA18776.1 23 KKRKNAATTA 32
                3333333332 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.00022
     DUF4805 145 savesereekve.qrtqksayptppststlttt..ansss.sGprekrryrrsq 194
                 s ++s ++ +v+  +++ +   tp st+t+ttt  a++ s s   +k+  ++s+
  EEA18776.1 376 SVSQS-QNSQVNvAEVRLPETATPASTTTTTTTttAAAKSeSKDDKKKEKKKSK 428
                 33333.333333145566666677776666544334333303333333334443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (441 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1773  (0.0988901); expected 358.6 (0.02)
Passed bias filter:                      584  (0.0325729); expected 358.6 (0.02)
Passed Vit filter:                        80  (0.00446204); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.44
# Mc/sec: 2991.18
//
Query:       EEA18777.1  [L=352]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.9e-19   69.5   0.0      5e-19   68.7   0.0    1.3  1  Methyltransf_16  Lysine methyltransferase
     0.0068   16.0   0.0      0.017   14.7   0.0    1.6  1  MTS              Methyltransferase small domain
  ------ inclusion threshold ------
       0.14   12.9   0.0       0.25   12.0   0.0    1.5  1  Methyltransf_25  Methyltransferase domain


Domain annotation for each model (and alignments):
>> Methyltransf_16  Lysine methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.7   0.0   8.3e-23     5e-19      15     163 ..     150     303 ..     143     314 .. 0.86

  Alignments for each domain:
  == domain 1  score: 68.7 bits;  conditional E-value: 8.3e-23
  Methyltransf_16  15 esigrkvWdaavvlvkylekklake.lganelsklsvlELGsGtGlvGlavaellpeakviltDlee.llellkk.nielnkn.alkskvkvev 104
                       s g   W+aa+ l +yl+  +++e l  ++ ++++++ELG+GtG v l  ++ l+  +v++tD +  l+++ +   +e n+  + k++++ ++
       EEA18777.1 150 GSTGFRTWEAALHLGTYLSSVSSDEpLSPASIRGKRIVELGAGTGFVSLLCQKFLGAERVLMTDGNAkLVDVFNGpCLEQNGFvKGKDAIEGRQ 243
                      5889999*************9988898999**********************************9875666665414555554567999***** PP

  Methyltransf_16 105 LdWgeeleedllekeevDlilaaDcvYledslelLvkvLkellkkesk..vlvaykkrrea 163
                        Wge+l  d + +e++D+   aD++Y++  ++lLv+ +++l +++++  +++a  +r+e+
       EEA18777.1 244 WLWGEPLSTDGT-EEQFDFACGADLTYDKAIIPLLVDAISRLFSSHGVkqFVIAATIRNEE 303
                      **********96.557****************************99988888888888764 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   2.8e-06     0.017      31      72 ..     182     223 ..     174     238 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 2.8e-06
                 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHH CS
         MTS  31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesak 72 
                 + ++++ lG+G+G++++ ++k+    +v ++d +a+ +++ +
  EEA18777.1 182 RGKRIVELGAGTGFVSLLCQKFLGAERVLMTDGNAKLVDVFN 223
                 5678******************************99887765 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   4.2e-05      0.25       1      43 [.     186     228 ..     186     289 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 4.2e-05
                      EEEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHH CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlgkakvtgvDiseemleaareraee 43 
                      +++lG+GtG ++l ++k lg+++v+++D ++++++  +  + e
       EEA18777.1 186 IVELGAGTGFVSLLCQKFLGAERVLMTDGNAKLVDVFNGPCLE 228
                      79***********9999989*************9998755544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (352 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       327  (0.0182386); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2486.96
//
Query:       EEA18778.1  [L=133]
Description: 37S ribosomal protein S24 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.5e-35  120.3   0.1    4.6e-35  119.4   0.0    1.5  2  Ribosomal_S24e  Ribosomal protein S24e
     0.0037   17.1   2.2     0.0043   16.9   2.1    1.2  1  RRXRR           RRXRR protein
  ------ inclusion threshold ------
      0.043   13.6   0.0      0.059   13.1   0.0    1.2  1  FAD_binding_4   FAD binding domain


Domain annotation for each model (and alignments):
>> Ribosomal_S24e  Ribosomal protein S24e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.4   0.0   7.8e-39   4.6e-35       1      78 [.      25     102 ..      25     103 .. 0.97
   2 ?    0.2   0.1      0.12   7.2e+02      59      77 ..      98     116 ..      97     118 .. 0.77

  Alignments for each domain:
  == domain 1  score: 119.4 bits;  conditional E-value: 7.8e-39
                     EEEEE-SSS-S--HHHHHHHHHHHHTS-CTTEEEEEEEE-SSSSEEEEEEEEES-HHHHHHHS-HHHHHHTTSS---S CS
  Ribosomal_S24e   1 vvdvlHpgkatpskteireklakmykvdpdlvvvfgfrthfGggkttGfakiYdsleaakkfEpkhrlaRnglaekkk 78 
                     vvdvlHp++a++sk+++r kla +yk+++d+v vfgfrt+fGggk+tGfa++Yds ea+kkfEp++rl+R g a k +
      EEA18778.1  25 VVDVLHPNRANVSKDDLRGKLADLYKANKDQVSVFGFRTQFGGGKSTGFALVYDSHEALKKFEPHYRLVRIGAAAKIE 102
                     79**********************************************************************999876 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.12
                     HHHHS-HHHHHHTTSS--- CS
  Ribosomal_S24e  59 akkfEpkhrlaRnglaekk 77 
                     a k+E+  r +R++ +   
      EEA18778.1  98 AAKIEKASRQQRKQRKNRS 116
                     7899999999998877655 PP

>> RRXRR  RRXRR protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   2.1   7.1e-07    0.0043      59     117 ..      67     126 ..      16     131 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 7.1e-07
       RRXRR  59 GskvtGiavv.sekkvllkaelelrgkdikkkleeRrelRraRRsrktryrqaRfdnRkk 117
                 G k tG+a+v ++++ l k e + r  +i  + +  ++ R++R++rk r ++ R   ++k
  EEA18778.1  67 GGKSTGFALVyDSHEALKKFEPHYRLVRIGAAAKIEKASRQQRKQRKNRSKKFRGTAKTK 126
                 77899***99667799*******************************9999988877766 PP

>> FAD_binding_4  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   9.8e-06     0.059      18      83 ..      47     110 ..      37     115 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 9.8e-06
                    HHHHHCTSCEEEESSSTTEESTTCSCCEEEEEETTS--EEEEETTTTEEEEETTSBHHHHHHHHHH CS
  FAD_binding_4  18 rlaneaglpvlvrGgGssllgqavatggvvldlsrlnrileideeegtatveaGvtlgdlvealaa 83 
                     l ++++ +v v+G  + ++g++  + g+ l  +  + + ++++ ++ ++++a ++++++ ++ ++
     EEA18778.1  47 DLYKANKDQVSVFGFRTQFGGGK--STGFALVYDSHEALKKFEPHYRLVRIGAAAKIEKASRQQRK 110
                    567889999***********777..5688887877888889*****************99998755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (133 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       809  (0.0451224); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.46
# Mc/sec: 873.16
//
Query:       EEA18779.1  [L=218]
Description: 37S ribosomal protein S24 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.9e-35  118.4   0.0    1.6e-34  117.7   0.0    1.3  1  Ribosomal_S24e  Ribosomal protein S24e


Domain annotation for each model (and alignments):
>> Ribosomal_S24e  Ribosomal protein S24e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.7   0.0   8.7e-39   1.6e-34       1      78 [.      25     102 ..      25     103 .. 0.97

  Alignments for each domain:
  == domain 1  score: 117.7 bits;  conditional E-value: 8.7e-39
                     EEEEE-SSS-S--HHHHHHHHHHHHTS-CTTEEEEEEEE-SSSSEEEEEEEEES-HHHHHHHS-HHHHHHTTSS---S CS
  Ribosomal_S24e   1 vvdvlHpgkatpskteireklakmykvdpdlvvvfgfrthfGggkttGfakiYdsleaakkfEpkhrlaRnglaekkk 78 
                     vvdvlHp++a++sk+++r kla +yk+++d+v vfgfrt+fGggk+tGfa++Yds ea+kkfEp++rl+R g a k +
      EEA18779.1  25 VVDVLHPNRANVSKDDLRGKLADLYKANKDQVSVFGFRTQFGGGKSTGFALVYDSHEALKKFEPHYRLVRIGAAAKIE 102
                     79**********************************************************************999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (218 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       309  (0.0172346); expected 358.6 (0.02)
Passed bias filter:                      258  (0.0143901); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.44
# Mc/sec: 1487.46
//
Query:       EEA18780.1  [L=973]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.3e-97  325.8   4.7      3e-94  316.7   0.9    2.2  2  ArAE_2_N         Putative ER transporter, 6TM, N-terminal
    9.3e-53  179.4   0.4    3.9e-51  174.1   0.2    2.3  2  ArAE_2           Aromatic acid exporter family member 2
    1.8e-11   44.3  14.6    1.8e-11   44.3  14.6    3.9  4  FUSC_2           Fusaric acid resistance protein-like
  ------ inclusion threshold ------
       0.56    9.8   3.7        1.4    8.6   3.7    1.6  1  Nup54_57_C       NUP57/Nup54 C-terminal domain
        2.6    6.8  15.1      0.048   12.5   7.5    1.8  2  ALMT             Aluminium activated malate transporter


Domain annotation for each model (and alignments):
>> ArAE_2_N  Putative ER transporter, 6TM, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  316.7   0.9   8.5e-98     3e-94      12     468 ..       8     452 ..       5     461 .. 0.90
   2 !   10.3   0.2   7.1e-05      0.26     203     323 ..     741     863 ..     739     876 .. 0.71

  Alignments for each domain:
  == domain 1  score: 316.7 bits;  conditional E-value: 8.5e-98
    ArAE_2_N  12 dlrsfKvifRswvavwvaiiLmvipptarwlGtaayLllivsvivpsGggsvivfilialllllgiclawawaviamkianrarpdaitqarlaqllie 110
                 + r  K+++R+wv+ wv+++Lm+i+p+++++G+a +++ ++ ++ p+ +g+ ++fi++a++l lg++law w+ i mk+a  arp a+ qa+l+ l++ 
  EEA18780.1   8 NTRVVKTLIRCWVPAWVGVVLMLIHPSLQRIGQASFFMIMIQMMCPP-AGIETIFIFTAFSLWLGMLLAWGWGSIVMKAAYSARPAADYQAQLQHLQQV 105
                 78899******************************************.*************************************************** PP

    ArAE_2_N 111 eglcantsgaelaacaqeqvydgkmltarvsvvyavllcvflffvgrlrakspkfalgaifgiIaadvfltyapmlPlfapgtlglallkPmgiglalk 209
                 +   an+sg   a++aq +vy+g+ml+arvs+v+ vl ++f++ +  lr k+pkf+++++fgiI++d+ lt++p+lP  ++gtl++ +++P+ igl+l 
  EEA18780.1 106 ASQRANQSGLPIATEAQALVYEGYMLDARVSAVFLVLGISFIYCISLLRMKNPKFIFTQLFGIIITDIYLTIGPLLPA-FNGTLPTLIIEPASIGLGLA 203
                 ******************************************************************************.******************** PP

    ArAE_2_N 210 vvvsllifPttssfqvlktmlkllkllkkalkfnsnflatlepsnesewlnfkklekditkirslypkleaelaflplEfsigrfsaedvkelrstlrr 308
                 +v+sll+fP+++s++ l+ m+k++  lk +lk + +   + e+  e++   +  ++++++++ ++ ++l+++++fl+l++sigr++ +d+++  + lr+
  EEA18780.1 204 FVASLLLFPQSTSHVTLDAMEKIVDMLKIPLKTTMEGPVEEEK--EAQV--LAGFNATKQGLLGQWNELQPMVGFLKLDLSIGRWNDKDITSVVQDLRK 298
                 *******************************988775555544..4543..689999****************************************** PP

    ArAE_2_N 309 lissiagLvyfydlleelravilkserssklaa....nghakldseieekk..revgayetkksielleardaqrsltlsdldeviealrelsgeilea 401
                   + ++ L++f +++   +    +s+++  l+     +++ +l+s  e+ k  +++g ++ ++    l+  ++++s   + ++e+   l e s+e++ea
  EEA18780.1 299 AFIGTTNLLNFQISRLGGTL---QSQKALALEPpttsSSEGQLTSLREKIKghKDIGFHQLNEFSVFLK--AINDSDNAAIRNETLTMLYENSTEVIEA 392
                 **********9999888855...555555555587532333333333333377*********9999999..9*************************** PP

    ArAE_2_N 402 veegletivewleaanefRiyslalpwnakkhkekqkeaaaeleeaketlekaledfakakrlklla 468
                   e+l+++ e+ +++n  R++s +  + +++h+++  +a ++l+        a+++f ++++++ll+
  EEA18780.1 393 SIEALDSVKECFHTVNTARMFSRPSQETQEQHVKRSETALENLR-------AARASFVEKTTEQLLE 452
                 **********************99999999**999965555555.......5555554444444443 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 7.1e-05
    ArAE_2_N 203 giglalkvvvsllifPttssfqvlktmlkllkllkkalkfnsnflatlepsnesewlnfkk.lekditkirslypkleaelaflplEfsigrfsaedvk 300
                 +igla +++v +l  P++ ++ v   +++ ++    +++  +  l++l +s++ +   +++ + ++ ++++s++ +l++  a++ lE+s + f+ + + 
  EEA18780.1 741 LIGLAASIIVQILPRPVSATRHVSRALSNSIRT---LCDHYALLLSSLGESHNPG---LQAvVGQLSIQLSSSLGALDMLIALIRLEISTTNFDSAALR 833
                 689999999999999999888887776665554...5666666666666666665...3551567889*****************************99 PP

    ArAE_2_N 301 elrs.......tlrrlissiagLvyfydll 323
                 ++++       +l+rl+  +++L+  y+ l
  EEA18780.1 834 KIKTlclelnySLGRLLYITSSLSIEYQEL 863
                 998711111114556666666666555555 PP

>> ArAE_2  Aromatic acid exporter family member 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0     0.021        74      57     119 ..     261     324 ..     235     327 .. 0.79
   2 !  174.1   0.2   1.1e-54   3.9e-51       1     229 []     754     963 ..     754     963 .. 0.97

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.021
      ArAE_2  57 vleklaglkgllvllkfElslkGrwpskkyar.lqalvselvqllarLlvvlkrle.peewlkrl 119
                 +l + ++l+++++ lk++ls  Grw+ k     +q+l +  + + + L + ++rl    + +k+l
  EEA18780.1 261 LLGQWNELQPMVGFLKLDLS-IGRWNDKDITSvVQDLRKAFIGTTNLLNFQISRLGgTLQSQKAL 324
                 55666789999*********.9****999876257888899999999999999997666666666 PP

  == domain 2  score: 174.1 bits;  conditional E-value: 1.1e-54
      ArAE_2   1 PrPksakrlvrktlaktlselgdlyckvlsfaaerlenphihikaerdqirkkilevleklaglkgllvllkfElslkGrwpskkyarlqalvselvql 99 
                 PrP+sa+r+v + l++++++l d+y+++ls  +e   +++  ++a    + + ++++ ++l  l++l++l+++E+s + +++s++++++++l+ el+  
  EEA18780.1 754 PRPVSATRHVSRALSNSIRTLCDHYALLLSSLGE---SHNPGLQAV---VGQLSIQLSSSLGALDMLIALIRLEIS-TTNFDSAALRKIKTLCLELNYS 845
                 9*********************************...555555555...779************************.********************** PP

      ArAE_2 100 larLlvvlkrlepeewlkrllrrvglldpeliadvlavlsmasqaLktGdpLPeilpapLvkrhlellrkqlkleeseeeadslaealslellrsedgr 198
                 l+rLl + ++l + e+++ l r+vgl ++++i+dv+avl++++q+LktGd+LPe+lp+pLvkr+++++ k+  +             +s  ++++e++r
  EEA18780.1 846 LGRLLYITSSL-SIEYQELLSREVGLRSHHAIGDVMAVLGVIEQSLKTGDALPEVLPTPLVKRCFDHWVKADINLV-----------MSMAKVKEEEYR 932
                 ***********.9*********************************************************999999...........************ PP

      ArAE_2 199 rfivalsialkildrlDelvlvvKglvGEky 229
                 +f+ als +l +l ++D+lvlv+K+ +GE++
  EEA18780.1 933 KFCTALSSYLRFLGAVDDLVLVMKETLGEAH 963
                 *****************************98 PP

>> FUSC_2  Fusaric acid resistance protein-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   1.0      0.19   6.8e+02      33      99 ..       8      73 ..       1     104 [. 0.52
   2 ?    1.9   1.2     0.063   2.2e+02      55      93 ..     129     169 ..     121     191 .. 0.73
   3 ?   -2.6   0.0       1.5   5.4e+03      29      49 ..     464     484 ..     461     498 .. 0.71
   4 !   44.3  14.6     5e-15   1.8e-11       7     127 .]     606     750 ..     600     750 .. 0.75

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.19
      FUSC_2 33 ltravqRilGtvlGavlallllyllpgnlalallvfllvfliafflk.rnyalafifltllalllysl 99
                +tr+v+ ++ + + a ++++l  ++p+ l+ +     ++++i ++   ++   + +++t++ l l +l
  EEA18780.1  8 NTRVVKTLIRCWVPAWVGVVLMLIHPS-LQRIGQASFFMIMIQMMCPpAGIETI-FIFTAFSLWLGML 73
                555555555555555555555555555.44444444444444333320222233.3334443333333 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.063
      FUSC_2  55 yllpgn..lalallvfllvfliafflkrnyalafifltlla 93 
                 y+l++    ++++l++ ++ +i++++ +n+ ++f+ l  ++
  EEA18780.1 129 YMLDARvsAVFLVLGISFIYCISLLRMKNPKFIFTQLFGII 169
                 66777634566677777777889999999988888765443 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 1.5
      FUSC_2  29 lgasltravqRilGtvlGavl 49 
                 + a +t + +R+  +++G+++
  EEA18780.1 464 VKAMNTHLRHRFRAVMFGMIF 484
                 667778888888888888876 PP

  == domain 4  score: 44.3 bits;  conditional E-value: 5e-15
      FUSC_2   7 ellgl.......wrgeWalitaaivlsptlgasltravqRilGtvlGavlallllyllpgn.....lalallvfll...vfliafflkrny..alafif 88 
                  + ++       +rg+Wali+a   +  ++++ +  ++ R +Gtv+G vl+l+++y+++g+     ++la+++ ++   ++++++fl r++   +++ +
  EEA18780.1 606 AVIPHtagffykQRGIWALIMAQTTMLAYMADFTYSVIGRAIGTVVGGVLGLVAWYIGSGKgdgnpFGLAAIIGVMlvpILYARVFLPRQFviPVIMGA 704
                 4444444446669*******************************************9997445557777766555522366668899999955557777 PP

      FUSC_2  89 ltllalllyslaa.......gsgnpie.....ialhRlldvliGiliallv 127
                  t+l+++ y + +                   i++ Rll vliG + +++v
  EEA18780.1 705 ATFLLVIGYGYDYkhvvsygL-----PgygyeIFWRRLLLVLIGLAASIIV 750
                 888888888884444554444.....055566**************99986 PP

>> Nup54_57_C  NUP57/Nup54 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   3.7   0.00038       1.4      10      19 ..      94     103 ..      93     104 .. 0.91

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00038
  Nup54_57_C  10 DYekQLqHLk 19 
                 DY+ QLqHL+
  EEA18780.1  94 DYQAQLQHLQ 103
                 *********8 PP

>> ALMT  Aluminium activated malate transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.8      0.42   1.5e+03     298     342 ..     388     437 ..     354     471 .. 0.51
   2 ?   12.5   7.5   1.3e-05     0.048      64     190 ..     643     775 ..     615     783 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.42
        ALMT 298 elqrvslesakvlrelaesvkkmkklsk.....veellkevkvaaeeLqs 342
                 e+ ++s+e+   ++e  + v++ +  s+     +e+++k  ++a+e+L++
  EEA18780.1 388 EVIEASIEALDSVKECFHTVNTARMFSRpsqetQEQHVKRSETALENLRA 437
                 33333333333334433333333321111001234444444444444443 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 1.3e-05
        ALMT  64 lnRalaTliAGglalgvselasssgkileeivigvsvFiiaalatflr.liPaikarYdYgvlvflLTFclvvvsgyrtdevielAv.........kRf 152
                 + Ra++T+++G+l+l++  + s  g+ ++++ +++++ ++   + ++r + P+   ++   v     TF lv+  gy  ++v+++           +R+
  EEA18780.1 643 IGRAIGTVVGGVLGLVAWYIGSGKGD-GNPFGLAAIIGVMLVPILYARvFLPR---QFVIPVIMGAATFLLVIGYGYDYKHVVSYGLpgygyeifwRRL 737
                 67************************.********************945587...58888888899999999999999999876532222222338** PP

        ALMT 153 ltiaiGaliclivsifvfPiwaGedLhklvaknlekla 190
                 l+++iG + ++iv i+  P+ a   + + +++++  l 
  EEA18780.1 738 LLVLIGLAASIIVQILPRPVSATRHVSRALSNSIRTLC 775
                 *********************99999999888888775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (973 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       890  (0.0496402); expected 358.6 (0.02)
Passed bias filter:                      556  (0.0310112); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.82u 0.32s 00:00:01.13 Elapsed: 00:00:00.49
# Mc/sec: 5997.13
//
Query:       EEA18781.1  [L=319]
Description: 2,3-dihydroxybenzoic acid decarboxylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.5e-39  135.8   0.1      3e-39  135.6   0.1    1.1  1  Amidohydro_2  Amidohydrolase


Domain annotation for each model (and alignments):
>> Amidohydro_2  Amidohydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  135.6   0.1   1.7e-43     3e-39      65     290 ..      68     316 ..      41     317 .. 0.92

  Alignments for each domain:
  == domain 1  score: 135.6 bits;  conditional E-value: 1.7e-43
                   HHHHHHHHHHHHHHHHCTTCBECEEECTSSHCHHHHHHHHHHHHTTECEEEEESSTTTCCTTTCGGHHHHHHHHHHHT-EEEEE............. CS
  Amidohydro_2  65 lcrgannrvlaeaakrpdrfvggaavvpldpedaaaeleraveelgfkGvrlnphvggddllgdrldrpifealeelglpvdihtGps......... 152
                   lc++an++++  ++++p rf+g+a ++  +p+ a++eler++ + +f+G  ++ h +g   +++ ++ p+fe+++el++p+++h  ps         
    EEA18781.1  68 LCQAANDELASAISANPTRFAGFALLPIAEPQLAVQELERCITQHKFVGALIDNHTNGQFYDDQKFW-PVFEKAQELDAPIYVH--PSypdeesgva 161
                   699****************************************************************.****************..55559999999 PP

                   ...............CHHHCHHHHHHHHHHHHHHHCCHHHHCTTSEEEESGGGTTTTCHHHHHHHHHHHHHCCEEECCGHHH....SSEEECCHHCH CS
  Amidohydro_2 153 ...............pewlfggpqettraiqplllsgvarkfPnlkivlaHgGgpserlraalellarrpnvyvklsglyte....llyfdspladp 230
                                  +++++g++++t+  i++l ++g+++ +Pn ki++ H+G +   l+  le++    + + + +gl +      + ++s  ++ 
    EEA18781.1 162 ahyrgnyddriaaalGAYGWGWHSDTALSILRLFAAGLFDTYPNIKIIIGHMGEM---LPFQLERVIGIASRFGRSRGLREVwtqnIWVTTSGMFAL 255
                   *******************************************************...55555555555555556666655577767788899999* PP

                   HHHHHHHHHH-GGGEEEE--BTSTTSTSCTTHHHHCHHHHH.SSHHHHHHHHTHHHHHHCT CS
  Amidohydro_2 231 palarlieavgpdrilfGsDyPhptleaepealalldlval.lsdeerekilggNAarlyg 290
                    +la l+++ + +r+l++ DyP+++ e   ++l ++ +  l    e+ e++l++NA +l++
    EEA18781.1 256 APLACLLQTMPIERVLYSVDYPFSANEKGFAFLEEIKKSGLiKEGEDWERFLYKNAQELLK 316
                   **************************************99999***************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (319 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       371  (0.0206927); expected 358.6 (0.02)
Passed bias filter:                      355  (0.0198003); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.31s 00:00:00.86 Elapsed: 00:00:00.50
# Mc/sec: 1922.44
//
Query:       EEA18782.1  [L=388]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.023   14.6   1.2       0.04   13.8   1.2    1.3  1  DUF2678   Protein of unknown function (DUF2678)
      0.031   12.9   1.7      0.044   12.5   1.7    1.1  1  EMP70     Endomembrane protein 70


Domain annotation for each model (and alignments):
>> DUF2678  Protein of unknown function (DUF2678)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   1.2   4.5e-06      0.04      22      73 ..     149     201 ..     140     212 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 4.5e-06
     DUF2678  22 etsardriinlvvggltsllvl.vtvvssfvfpslppkplniffavcilliss 73 
                 + + r+++i  +v gl  l+++   +v ++ f +l+ ++  iff++ i++i++
  EEA18782.1 149 DRFVRKHLIICAVTGLLLLMLIsLYLVYAISFTTLEGQTYHIFFILLIMIIAM 201
                 567788888888877766554416799*******************9999875 PP

>> EMP70  Endomembrane protein 70
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   1.7   4.9e-06     0.044     397     468 ..     133     205 ..     121     214 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 4.9e-06
       EMP70 397 iehpvrtnqiprqipkqpwylkpllsvllgGilpFgaifielyfilsslwle.kiYylfgfLflvfllliitt 468
                 i  p++++   r   k ++++k+l+ ++++G+l  + i + l++ +s   le ++Y++f +L+++++ ++   
  EEA18782.1 133 IAPPSKIKDAYRIALKDRFVRKHLIICAVTGLLLLMLISLYLVYAISFTTLEgQTYHIFFILLIMIIAMVFCH 205
                 467888888888777899*********************999999888777758*****99999999888654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (388 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1514  (0.0844442); expected 358.6 (0.02)
Passed bias filter:                      678  (0.0378158); expected 358.6 (0.02)
Passed Vit filter:                        84  (0.00468515); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.34s 00:00:00.98 Elapsed: 00:00:00.49
# Mc/sec: 2388.23
//
Query:       EEA18783.1  [L=358]
Description: U5 snRNP complex subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.3e-44  147.6  10.4    1.1e-05   26.1   0.0    7.3  7  WD40           WD domain, G-beta repeat
      9e-13   48.4   0.2    0.00079   19.7   0.0    5.0  6  ANAPC4_WD40    Anaphase-promoting complex subunit 4 WD40 doma
     0.0052   16.1   0.0        8.5    5.6   0.1    3.3  4  WD40_like      WD40-like domain
  ------ inclusion threshold ------
      0.018   13.7   0.2        1.3    7.6   0.0    2.5  2  Nup160         Nucleoporin Nup120/160
      0.057   13.0   0.3          6    6.4   0.0    2.5  2  PQQ_2          PQQ-like domain
       0.19   10.4   0.6        3.7    6.2   0.1    2.5  2  Nucleoporin_N  Nup133 N terminal like


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.1   0.0   3.7e-09   1.1e-05       3      37 ..      57      92 ..      55      93 .. 0.90
   2 !   23.3   0.2   2.7e-08   8.2e-05       4      38 .]     101     136 ..      98     136 .. 0.90
   3 !   23.3   0.0   2.8e-08   8.2e-05       2      38 .]     141     179 ..     140     179 .. 0.83
   4 !   14.8   0.1   1.4e-05     0.041      12      38 .]     194     220 ..     187     220 .. 0.92
   5 !   25.8   0.4   4.5e-09   1.3e-05       4      38 .]     227     262 ..     224     262 .. 0.89
   6 !   16.2   0.0     5e-06     0.015       5      38 .]     274     312 ..     271     312 .. 0.71
   7 !   18.5   0.0     9e-07    0.0027       1      36 [.     316     353 ..     316     353 .. 0.82

  Alignments for each domain:
  == domain 1  score: 26.1 bits;  conditional E-value: 3.7e-09
                EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40  3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37
                ++ +ltGH + v + +f+p  + +asGs+D+t+++W
  EEA18783.1 57 PIMELTGHsGEVFATRFDPTAQSIASGSMDRTIMLW 92
                6789****555************************* PP

  == domain 2  score: 23.3 bits;  conditional E-value: 2.7e-08
                 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                  ++ltGH + v +l++s+d+++++s+s D tv  Wd
  EEA18783.1 101 YGVLTGHkGAVLDLQWSRDSRFIFSASADMTVASWD 136
                 5789***655**********************9998 PP

  == domain 3  score: 23.3 bits;  conditional E-value: 2.8e-08
                 EEEEEEESSSS.EEEEEEETTSSEE.EEEETTSEEEEEE CS
        WD40   2 qclrtltGHss.vtslafspdgawl.asGsdDgtvriWd 38 
                 q +r+ +GH   +++l+ s+ g+ l +sGsdDg + iWd
  EEA18783.1 141 QRIRKHEGHEEvINCLDISKRGQELlVSGSDDGYIGIWD 179
                 6678889**5557****99999996269**********9 PP

  == domain 4  score: 14.8 bits;  conditional E-value: 1.4e-05
                 SEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  12 svtslafspdgawlasGsdDgtvriWd 38 
                 ++t++a s+ g+ +++G+ D+ +++Wd
  EEA18783.1 194 PITAVALSDAGNEIFTGGIDNDIKVWD 220
                 59************************9 PP

  == domain 5  score: 25.8 bits;  conditional E-value: 4.5e-09
                 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   4 lrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 
                 +++l GH++ +tsl+ spd++ l+s s D tvr Wd
  EEA18783.1 227 VYSLIGHNDtITSLQISPDSQTLLSNSHDSTVRTWD 262
                 67899**666**************8777*******9 PP

  == domain 6  score: 16.2 bits;  conditional E-value: 5e-06
                 EEEESSSSEEEEE.......EETTSSEEEEEETTSEEEEEE CS
        WD40   5 rtltGHssvtsla.......fspdgawlasGsdDgtvriWd 38 
                 rt++G  +v ++        ++p g  +a+Gs D++v +Wd
  EEA18783.1 274 RTFDGA-PV-GIEknlirasWDPKGEKIAAGSGDRSVVVWD 312
                 566666.32.2223333444***********99*******9 PP

  == domain 7  score: 18.5 bits;  conditional E-value: 9e-07
                 TEEEEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEE CS
        WD40   1 gqclrtltGH.ssvtslafspdgawl.asGsdDgtvri 36 
                 g++l++l GH + v++++fsp+   + +sGs D+++++
  EEA18783.1 316 GKLLYKLPGHkGTVNDVRFSPNDEPIiVSGSSDRNIML 353
                 688999****555*****88888885269988***986 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0       1.4   4.1e+03      58      81 ..      30      53 ..      27      62 .. 0.80
   2 !   19.7   0.0   2.7e-07   0.00079       4      88 ..      74     157 ..      71     161 .. 0.85
   3 ?    1.9   0.0      0.09   2.7e+02      36      70 ..     148     183 ..     145     192 .. 0.73
   4 !    7.1   0.0    0.0022       6.7      38      88 ..     192     241 ..     189     245 .. 0.89
   5 ?    2.7   0.0     0.051   1.5e+02      38      67 ..     234     263 ..     231     265 .. 0.90
   6 !   13.8   0.0   1.8e-05     0.054      44      89 ..     290     334 ..     274     337 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 1.4
  ANAPC4_WD40 58 sdgevrlldaesgkvvhslsvkse 81
                 + ++v l + ++g++v++++ +s 
   EEA18783.1 30 KSNAVTLRSGQNGTLVQAIPRTSG 53
                 578999999999999999987766 PP

  == domain 2  score: 19.7 bits;  conditional E-value: 2.7e-07
  ANAPC4_WD40   4 cptmDLiAlatedgellvfRlngq.rvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclg 88 
                   pt   iA ++ d  +++ R+  q + +++  +++++ v +L+W+ d +++  a +d +v   d e+g+ +++ + ++e  ++cl+
   EEA18783.1  74 DPTAQSIASGSMDRTIMLWRTYEQcENYGV-LTGHKGAVLDLQWSRDSRFIFSASADMTVASWDLETGQRIRKHEGHEE-VINCLD 157
                  577777888999999999999666245555.68899*************************************999988.699986 PP

  == domain 3  score: 1.9 bits;  conditional E-value: 0.09
  ANAPC4_WD40  36 kedsevrsLaWkpdgk.lLavaysdgevrlldaesg 70 
                  ++++ +++L  ++ g+ lL+ + +dg + + d  ++
   EEA18783.1 148 GHEEVINCLDISKRGQeLLVSGSDDGYIGIWDPRQK 183
                  566778899998888636677788899999887665 PP

  == domain 4  score: 7.1 bits;  conditional E-value: 0.0022
  ANAPC4_WD40  38 dsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclg 88 
                  d  ++++a +  g+ +  +  d+ +++ d+ ++ vv sl  +++ ++t+l+
   EEA18783.1 192 DFPITAVALSDAGNEIFTGGIDNDIKVWDIRKKAVVYSLIGHND-TITSLQ 241
                  6689999999*****************************98888.598886 PP

  == domain 5  score: 2.7 bits;  conditional E-value: 0.051
  ANAPC4_WD40  38 dsevrsLaWkpdgklLavaysdgevrllda 67 
                  + +++sL+ +pd + L    +d++vr  d+
   EEA18783.1 234 NDTITSLQISPDSQTLLSNSHDSTVRTWDI 263
                  678**********************98876 PP

  == domain 6  score: 13.8 bits;  conditional E-value: 1.8e-05
  ANAPC4_WD40  44 LaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                   +W p+g+ +a +  d +v + da+sgk++ +l+ ++  +v+ + +
   EEA18783.1 290 ASWDPKGEKIAAGSGDRSVVVWDAKSGKLLYKLPGHKG-TVNDVRF 334
                  48*******************************99988.4766655 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.3   0.0    0.0071        21       2     104 ..      67     175 ..      66     180 .. 0.69
   2 ?   -0.1   0.0      0.15   4.6e+02     256     275 ..     172     191 ..     157     196 .. 0.84
   3 !    5.6   0.1    0.0029       8.5       3      64 ..     195     257 ..     193     264 .. 0.81
   4 ?    1.5   0.0     0.052   1.6e+02      10      67 ..     294     353 ..     289     357 .. 0.82

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.0071
   WD40_like   2 eiYsidiskkgslilyGgkddkctvlkleslesvs.ivesfedSvifvkllddd.lilvvtlDGtillslleneeevenekieedistv.kvid..dk. 94 
                 e+++  +++ ++ i+ G+ d ++ +  +  +++ + ++++ +  v+  +   d   i  ++ D t+   +le ++ +++++ +e++  + ++ +  ++ 
  EEA18783.1  67 EVFATRFDPTAQSIASGSMDRTIMLWRTYEQCENYgVLTGHKGAVLDLQWSRDSrFIFSASADMTVASWDLETGQRIRKHEGHEEVINClDISKrgQEl 165
                 677777888888899999999999988766665542778899999988888777466678999999999999999998887766654441333211331 PP

   WD40_like  95 lliGtnkGsi 104
                 l+ G++ G i
  EEA18783.1 166 LVSGSDDGYI 175
                 3445556655 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.15
   WD40_like 256 cgkvgigDiRdketfklles 275
                 +g++gi D R+k ++ ++e+
  EEA18783.1 172 DGYIGIWDPRQKAALDFIET 191
                 799**********9999986 PP

  == domain 3  score: 5.6 bits;  conditional E-value: 0.0029
   WD40_like   3 iYsidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvkllddd.lilvvtlDGt 64 
                 i ++ +s  g+ i  Gg d+ ++v +++ + +v+++ + +d +   ++  d   +l  + D t
  EEA18783.1 195 ITAVALSDAGNEIFTGGIDNDIKVWDIRKKAVVYSLIGHNDTITSLQISPDSqTLLSNSHDST 257
                 66899999******************************9999987766544435555666655 PP

  == domain 4  score: 1.5 bits;  conditional E-value: 0.052
   WD40_like  10 kkgslilyGgkddkctvlkleslesvsivesfedSvifvkllddd..lilvvtlDGtill 67 
                 +kg+ i+ G+ d  + v + +s+++ + + + +  v  v++  +d   i+ ++ D +i+l
  EEA18783.1 294 PKGEKIAAGSGDRSVVVWDAKSGKLLYKLPGHKGTVNDVRFSPNDepIIVSGSSDRNIML 353
                 68899999**************99999999999999999999888544555677777765 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   0.0   0.00043       1.3     226     255 ..     117     145 ..     107     164 .. 0.88
   2 ?    3.1   0.1      0.01        30     229     271 ..     203     250 ..     179     261 .. 0.72

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.00043
                 ...TTTEEEEEETT-EEEEEETTTTEEEEE CS
      Nup160 226 veigqtylfalsrdgkLrvWnlltgkclat 255
                 ++ ++ ++f++s d ++  W+l+tg++++ 
  EEA18783.1 117 SR-DSRFIFSASADMTVASWDLETGQRIRK 145
                 45.899********************9976 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.01
                 TTTEEEEEETT-EEEEEETTTTEEEEE.EE--.....-SSSTTS--SS CS
      Nup160 229 gqtylfalsrdgkLrvWnlltgkclat.idll....rdeeaqdesssk 271
                 + + +f+   d+ ++vW+++ + ++++ i  +      ++++d+++  
  EEA18783.1 203 AGNEIFTGGIDNDIKVWDIRKKAVVYSlIGHNdtitSLQISPDSQTLL 250
                 5566888889***************99888775544445555544444 PP

>> PQQ_2  PQQ-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.2    0.0095        28     133     235 ..      30     144 ..       6     146 .. 0.62
   2 ?    6.4   0.0     0.002         6      35      64 ..     295     324 ..     269     352 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.0095
       PQQ_2 133 klvaldpkdGkvlWerel.aaprgtselsrvgdisgrpvva....egtVyassgqgrllaldlatgr.....rlw.skeiss.............ingl 207
                 k +a+ +++G+    + + a pr ts         ++p+++    +g+V+a +++   +a  +a+g+      lw + e                +  l
  EEA18783.1  30 KSNAVTLRSGQN--GTLVqAIPR-TS-------GLAAPIMEltghSGEVFATRFDP--TAQSIASGSmdrtiMLWrTYE--QcenygvltghkgaVLDL 114
                 445555555555..222324444.33.......24677777766577999999988..888888888777643363222..134467777777776666 PP

       PQQ_2 208 pil.dgdllyvvsa.gelialdratGavlW 235
                 ++  d ++++  sa  ++  +d++tG++++
  EEA18783.1 115 QWSrDSRFIFSASAdMTVASWDLETGQRIR 144
                 666244566766656999999999999876 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.002
       PQQ_2  35 sggtlfvatgggrlvaldaatGkvlWettl 64 
                 +g ++++++g + +v +da++Gk+l +   
  EEA18783.1 295 KGEKIAAGSGDRSVVVWDAKSGKLLYKLPG 324
                 577888999999999999999999987655 PP

>> Nucleoporin_N  Nup133 N terminal like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0     0.028        84     212     240 ..     119     144 ..     102     223 .. 0.70
   2 ?    6.2   0.1    0.0012       3.7     201     231 ..     234     264 ..     229     277 .. 0.93

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.028
                    CTCEEEEEETTSEEEEEEEETTCEE-EEE CS
  Nucleoporin_N 212 srrilytlsskgvirvydlsasngesslk 240
                     +r ++++s+++++  +dl++ +    ++
     EEA18783.1 119 DSRFIFSASADMTVASWDLETGQR---IR 144
                    448889999999999999995443...22 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.0012
                    GG-EEEEEEECCTCEEEEEETTSEEEEEEEE CS
  Nucleoporin_N 201 reeivqlridssrrilytlsskgvirvydls 231
                    +++i++l i++ ++ l + s ++++r++d+ 
     EEA18783.1 234 NDTITSLQISPDSQTLLSNSHDSTVRTWDIR 264
                    699**************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (358 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       288  (0.0160634); expected 358.6 (0.02)
Passed bias filter:                      281  (0.0156729); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.59u 0.26s 00:00:00.85 Elapsed: 00:00:00.48
# Mc/sec: 2243.54
//
Query:       EEA18784.1  [L=192]
Description: TRAPP complex component Bet3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.9e-36  124.4   0.0    3.6e-36  124.1   0.0    1.1  1  TRAPP     Transport protein particle (TRAPP) component


Domain annotation for each model (and alignments):
>> TRAPP  Transport protein particle (TRAPP) component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  124.1   0.0     2e-40   3.6e-36       2     145 ..      28     177 ..      27     178 .. 0.93

  Alignments for each domain:
  == domain 1  score: 124.1 bits;  conditional E-value: 2e-40
       TRAPP   2 afllgelvsylqrdsk.dveevekrLekmGyrvGlrllelllarer.pretdilevlkfickdlWkllfgkqidnlktnhrge...yvltdnefpltrf 95 
                 ++++g +v++l++d++ d+ ev+k+L+kmGy++G+rl+e++la+++  r  +++e++++i+k+++k++++++++++++ ++++   +vl++n  pl++f
  EEA18784.1  28 TLTYGTIVAQLCQDYDgDYLEVNKQLDKMGYNIGMRLIEDFLAKSNtGRCANFKETADIISKVGFKIFLNITPTVTNWTSDNKqfsLVLDEN--PLADF 124
                 799************7589*************************8879*******************************99888889*****..***** PP

       TRAPP  96 velpke..ls....ylaflcGiirGaLenlgfpakVtahelpsdelrgrttfeikv 145
                 velp++  ++    ++++lcG++rGaLe+++++   +ah + sd+lrg  t+ei+v
  EEA18784.1 125 VELPDDdrAQdqlwFSNILCGVLRGALEMVQMQ--AEAHFV-SDVLRGSDTTEIRV 177
                 ****9998557899*******************..666556.67**********98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (192 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      431  (0.0240393); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.28s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1290.01
//
Query:       EEA18785.1  [L=764]
Description: cAMP-dependent protein kinase pathway protein (Som1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (764 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1261  (0.070333); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.83u 0.34s 00:00:01.17 Elapsed: 00:00:00.53
# Mc/sec: 4364.20
//
Query:       EEA18786.1  [L=638]
Description: hypothetical protein PMAA_010650 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (638 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       545  (0.0303977); expected 358.6 (0.02)
Passed bias filter:                      425  (0.0237046); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.61u 0.31s 00:00:00.92 Elapsed: 00:00:00.47
# Mc/sec: 4082.40
//
Query:       EEA18787.1  [L=562]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (562 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       685  (0.0382063); expected 358.6 (0.02)
Passed bias filter:                      258  (0.0143901); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 3669.88
//
Query:       EEA18788.1  [L=392]
Description: mRNA binding post-transcriptional regulator (Csx1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.4e-45  151.7   0.0    7.2e-17   61.0   0.0    3.1  3  RRM_1         RNA recognition motif. (a.k.a. RRM, RBD, or RNP
    5.6e-05   23.1   0.0     0.0012   18.9   0.0    2.6  3  RRM_3         RNA binding motif
    7.7e-05   22.5   0.0      0.054   13.4   0.0    2.7  3  RRM_occluded  Occluded RNA-recognition motif
     0.0002   21.3   0.1     0.0015   18.5   0.0    2.3  3  Nup35_RRM_2   Nup53/35/40-type RNA recognition motif
    0.00061   19.8   0.3      0.049   13.8   0.0    2.8  3  RRM_7         RNA recognition motif
     0.0078   15.8   0.0      0.054   13.1   0.0    2.2  3  RRM_5         RNA recognition motif. (a.k.a. RRM, RBD, or RNP
  ------ inclusion threshold ------
        2.8    8.1   7.2        9.5    6.4   7.2    2.0  1  Statherin     Statherin


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.4   0.0   1.1e-11   2.9e-08       1      67 [.      61     127 ..      61     128 .. 0.95
   2 !   53.9   0.0   4.5e-18   1.2e-14       1      69 [.     155     225 ..     155     226 .. 0.97
   3 !   61.0   0.0   2.8e-20   7.2e-17       1      69 [.     283     346 ..     283     347 .. 0.97

  Alignments for each domain:
  == domain 1  score: 33.4 bits;  conditional E-value: 1.1e-11
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggr 67 
                 l++g L p ++e+ ++ l  + G+ +++k++rd   g++ g++fV+F s  +A kAl+ lng+ ++++
  EEA18788.1  61 LWMGELEPWIDENFIRNLWFQMGEQVNVKMIRDkFSGSNAGYCFVDFSSAAAAGKALS-LNGTPMPNT 127
                 6789999999************************************************.***998876 PP

  == domain 2  score: 53.9 bits;  conditional E-value: 4.5e-18
                 EEEESETTTSSHHHHHHHHHT.TSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFsk.fGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrel 69 
                 +fVg+L p+v+e  L  lF+  f + ks+k+++d   g s+g++fV+F ++ d ++Al++++g   g+r++
  EEA18788.1 155 IFVGDLGPEVNEYVLVSLFQSrFPSCKSAKIMTDpISGMSRGYGFVRFSDENDQQRALSEMQGVYCGNRPM 225
                 8**************************************************************99999987 PP

  == domain 3  score: 61.0 bits;  conditional E-value: 2.8e-20
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkklggrel 69 
                 +fVg+L+ +vte+eL+ +F++fG+i+ +k+++      kg++fV+F ++ +Ae A+++++g+ +g++++
  EEA18788.1 283 VFVGGLSGYVTEDELRSFFQGFGEITYVKIPPG-----KGCGFVQFVQRHAAEMAINQMQGYPIGNSRV 346
                 8*******************************7.....****************************987 PP

>> RRM_3  RNA binding motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0      0.45   1.1e+03       9      41 ..      82     115 ..      78     118 .. 0.80
   2 ?   -0.4   0.0      0.48   1.2e+03      40      57 ..     198     215 ..     193     222 .. 0.86
   3 !   18.9   0.0   4.5e-07    0.0012       4      58 ..     283     337 ..     281     349 .. 0.92

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.45
                 -SSS--HHHHHHHCHCCS.-ECEEEE-TTSSEEE CS
       RRM_3   9 lnkelsredikellsklg.evayvdyekgdkege 41 
                 +++++ ++ i++ +s  +    +vd+++ ++ g+
  EEA18788.1  82 MGEQVNVKMIRDKFSGSNaGYCFVDFSSAAAAGK 115
                 5678888999999998875788999999998886 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.48
                 EEEEESSHHHHHHHHHHH CS
       RRM_3  40 gevrFkedeeakkaleka 57 
                 g vrF ++++ ++al ++
  EEA18788.1 198 GFVRFSDENDQQRALSEM 215
                 789*******99998765 PP

  == domain 3  score: 18.9 bits;  conditional E-value: 4.5e-07
                 EEEEE-SSS--HHHHHHHCHCCS-ECEEEE-TTSSEEEEEESSHHHHHHHHHHHH CS
       RRM_3   4 lklsGlnkelsredikellsklgevayvdyekgdkegevrFkedeeakkalekat 58 
                 +++ Gl+  ++ ++++ +++ +ge+ yv    g+  g v+F + ++a+ a++++ 
  EEA18788.1 283 VFVGGLSGYVTEDELRSFFQGFGEITYVKIPPGKGCGFVQFVQRHAAEMAINQMQ 337
                 678899999*****************************************99865 PP

>> RRM_occluded  Occluded RNA-recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.8   0.0    0.0047        12      36      65 ..      98     126 ..      73     129 .. 0.79
   2 ?   -1.9   0.0       1.2   3.1e+03      42      72 ..     199     229 ..     198     231 .. 0.87
   3 !   13.4   0.0   2.1e-05     0.054       3      70 ..     282     348 ..     280     352 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0047
  RRM_occluded  36 pdheGAivefkdekiagkasLaLdgsefeg 65 
                   ++ + ++v f+++++agka L+L+g+ + +
    EEA18788.1  98 SNAGYCFVDFSSAAAAGKA-LSLNGTPMPN 126
                   5666699***********7.8999986655 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 1.2
  RRM_occluded  42 ivefkdekiagkasLaLdgsefegkklrcGt 72 
                   +v f+de++  +a+ +++g    ++ +r++t
    EEA18788.1 199 FVRFSDENDQQRALSEMQGVYCGNRPMRIST 229
                   5899999999999999999999999999887 PP

  == domain 3  score: 13.4 bits;  conditional E-value: 2.1e-05
  RRM_occluded   3 tisllplsDtvnkariralveekegeikkivLvpdheGAivefkdekiagkasLaLdgsefegkklrc 70 
                   t+ + +ls  v+++++r++++   gei+ + + p +++ +v+f ++++a  a+ +++g+ + + ++r 
    EEA18788.1 282 TVFVGGLSGYVTEDELRSFFQGF-GEITYVKIPPGKGCGFVQFVQRHAAEMAINQMQGYPIGNSRVRL 348
                   5566679999*************.*********************9999999999***9999988775 PP

>> Nup35_RRM_2  Nup53/35/40-type RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       3.6   9.2e+03      39      53 .]     103     117 ..      98     117 .. 0.85
   2 ?   -0.3   0.0      0.43   1.1e+03      38      53 .]     197     212 ..     184     212 .. 0.87
   3 !   18.5   0.0   5.7e-07    0.0015      14      52 ..     294     332 ..     280     333 .. 0.80

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 3.6
  Nup35_RRM_2  39 myvkfesekdaekAL 53 
                   +v f s  +a kAL
   EEA18788.1 103 CFVDFSSAAAAGKAL 117
                  689999999999998 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.43
  Nup35_RRM_2  38 vmyvkfesekdaekAL 53 
                  + +v+f +e d ++AL
   EEA18788.1 197 YGFVRFSDENDQQRAL 212
                  679***********98 PP

  == domain 3  score: 18.5 bits;  conditional E-value: 5.7e-07
  Nup35_RRM_2  14 ielVlehFasfGeIvkhyvpkevsvmyvkfesekdaekA 52 
                  +++ + +F+ fGeI+   +p+++   +v+f  + +ae+A
   EEA18788.1 294 EDELRSFFQGFGEITYVKIPPGKGCGFVQFVQRHAAEMA 332
                  345677********************************9 PP

>> RRM_7  RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       2.4     6e+03      45      61 ..      95     111 ..      81     118 .. 0.69
   2 ?    3.0   0.0     0.043   1.1e+02       4      69 ..     155     214 ..     153     239 .. 0.66
   3 !   13.8   0.0   1.9e-05     0.049       3      32 ..     282     312 ..     280     339 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 2.4
       RRM_7  45 nskaakgyvflvfedek 61 
                  s ++ gy f+ f++  
  EEA18788.1  95 FSGSNAGYCFVDFSSAA 111
                 45667899998887655 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.043
       RRM_7   4 vFvGGlPiDiteeelkatfkefgkvlvdwPkkaeskkkaaenskaakgyvflvfedeksvkaLlea 69 
                 +FvG l ++++e  l++ f++       +P  +  k  +   s   +gy f+ f+de+  ++ l++
  EEA18788.1 155 IFVGDLGPEVNEYVLVSLFQS------RFPSCKSAKIMTDPISGMSRGYGFVRFSDENDQQRALSE 214
                 788888888888888888875......344443333333334445678888888888776666655 PP

  == domain 3  score: 13.8 bits;  conditional E-value: 1.9e-05
       RRM_7   3 kvFvGGlPiDiteeelkatfkefgkvl.vdw 32 
                  vFvGGl   +te+el + f+ fg+++ v  
  EEA18788.1 282 TVFVGGLSGYVTEDELRSFFQGFGEITyVKI 312
                 69**********************9752555 PP

>> RRM_5  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       1.1   2.8e+03      58      80 ..      94     116 ..      77     127 .. 0.55
   2 ?   -1.5   0.0       0.7   1.8e+03      65      89 ..     196     220 ..     191     234 .. 0.79
   3 !   13.1   0.0   2.1e-05     0.054      10     102 ..     265     354 ..     257     365 .. 0.83

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 1.1
       RRM_5  58 kflktkketalvqmgdasavera 80 
                 kf  +  ++ +v+ ++a a+ +a
  EEA18788.1  94 KFSGSNAGYCFVDFSSAAAAGKA 116
                 44444555556666665555555 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.7
       RRM_5  65 etalvqmgdasaveravqHLnnakl 89 
                 ++ +v  +d+ + +ra++ ++++  
  EEA18788.1 196 GYGFVRFSDENDQQRALSEMQGVYC 220
                 77889999999*****999999866 PP

  == domain 3  score: 13.1 bits;  conditional E-value: 2.1e-05
       RRM_5  10 asvaatgspgaagvaegsVllVyglepdkvnldklFnlfclYgnvervkflktkketalvqmgdasaveravqHLnnaklfgkrlevalSKqq 102
                  ++a +++  +   ++++ ++V gl    v+ d+l  +f  +g++  vk+    k+  +vq  +  a+e a++ +++ ++ ++r+++   + q
  EEA18788.1 265 FYGAPQPM-NQFTDPNNTTVFVGGLS-GYVTEDELRSFFQGFGEITYVKIPP-GKGCGFVQFVQRHAAEMAINQMQGYPIGNSRVRLSWGRSQ 354
                 56666666.455667899999***96.689*******************965.579************************8889888776655 PP

>> Statherin  Statherin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   7.2    0.0037       9.5      20      41 .]     363     384 ..     352     384 .. 0.94

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0037
   Statherin  20 PYQpfpeqPLYPQPYQPqyqQY 41 
                 PY p p++P+YP    P+  QY
  EEA18788.1 363 PYRPAPPPPIYPNMGMPPAHQY 384
                 9*************99999999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (392 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       349  (0.0194657); expected 358.6 (0.02)
Passed bias filter:                      278  (0.0155056); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 2636.36
//
Query:       EEA18789.1  [L=272]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-55  188.0   0.7    1.5e-55  187.5   0.0    1.5  2  TFB6      Subunit 11 of the general transcription factor TFII
  ------ inclusion threshold ------
        1.2    9.5   8.1        5.1    7.5   1.2    2.3  2  PBP1_TM   Transmembrane domain of transglycosylase PBP1 at N-


Domain annotation for each model (and alignments):
>> TFB6  Subunit 11 of the general transcription factor TFIIH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.1       0.3   2.7e+03     124     134 ..      81      91 ..      56      95 .. 0.49
   2 !  187.5   0.0   1.7e-59   1.5e-55       1     171 []      96     261 ..      96     261 .. 0.87

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.3
        TFB6 124 edeeededeee 134
                 +++ +d+d++e
  EEA18789.1  81 QNDVDDKDKDE 91 
                 12222222222 PP

  == domain 2  score: 187.5 bits;  conditional E-value: 1.7e-59
        TFB6   1 GYeslkellkdldklvdvlWvSgtpslqipyLlniaselldylekfp.pspratfklLrkLDkiFasLlaGeDvetgetlpGfeeglragmstTdkVRl 98 
                 GYes+ke++kd+++++dv+WvSgtps+qipyL+++a  +++yl+++p ++p++tf+lL+kLD +FasLl GeDve+g +l+Gfe  +++ +s+T+kVR+
  EEA18789.1  96 GYESFKEVVKDIEEVIDVVWVSGTPSIQIPYLISLAGLVNTYLPEYPhFQPKPTFRLLKKLDIMFASLLLGEDVESGVPLSGFE-YTKNIVSMTEKVRI 193
                 9*********************************************9679999******************************5.569*********** PP

        TFB6  99 ksivertRvlvvevlereeeeeeeeedeeededeeeeeeeeeeeeeeedeededeelemevarvYektleklG 171
                 ksi+e +R++vv++ er+ e ++ +  +e++++     e+  + +e++ e+++   +eme+a+vYe+t++ lG
  EEA18789.1 194 KSIAEASRIVVVDMRERDVEYQD-DIGDESENE----WEDGMDIDESDFETSHAGLWEMEAAKVYERTIQYLG 261
                 *****************966666.322222222....233333445555567999***************998 PP

>> PBP1_TM  Transmembrane domain of transglycosylase PBP1 at N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.9     0.002        18      29      55 ..      68      93 ..      54     105 .. 0.56
   2 ?    7.5   1.2   0.00057       5.1      28      53 ..     207     236 ..     192     256 .. 0.67

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.002
     PBP1_TM 29 rrrdddyddeyddeedDdddddeeeev 55
                rr+   ++  +dd ++D dd+d +ee 
  EEA18789.1 68 RRHAKKFNGVIDD-QNDVDDKDKDEEQ 93
                4445555553333.3333333322222 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.00057
     PBP1_TM  28 rrrr....dddyddeyddeedDdddddeee 53 
                  r r    +dd+ de ++e++D  d de++
  EEA18789.1 207 MRERdveyQDDIGDESENEWEDGMDIDESD 236
                 444411226666668888888887777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (272 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       612  (0.0341346); expected 358.6 (0.02)
Passed bias filter:                      448  (0.0249875); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.23s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2030.23
//
Query:       EEA18790.1  [L=153]
Description: phosphoglycerate mutase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    8.9e-15   54.9   1.0    1.4e-14   54.2   1.0    1.3  1  His_Phos_1  Histidine phosphatase superfamily (branch 1)


Domain annotation for each model (and alignments):
>> His_Phos_1  Histidine phosphatase superfamily (branch 1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.2   1.0     8e-19   1.4e-14      39     136 ..      21     125 ..      13     129 .. 0.85

  Alignments for each domain:
  == domain 1  score: 54.2 bits;  conditional E-value: 8e-19
                 HHTTS---EEEE-SSHHHHHHHHHHHHCTT.....--EEE-GGGS----GGGTT-B.HHHHHH..HSHHHHHHHHH-GGG-B...S-BHHHHHHHHHHH CS
  His_Phos_1  39 rlagepidaiysSplkRarqTaeliaealg.....lpveldegLrEidfGdweglttaeiaeeypeeleawlrdpadvrppg...gEsledvaaRvaaa 129
                  +   +i++i++Sp kRa+qT +l+ +  g       ve+ e++ E+d+Gd+egl   e++++++e+  ++++d++  + +g   gEs ++v++R+++ 
  EEA18790.1  21 LIDPTRIARIWVSPRKRAQQTFRLLFDVDGrddygNLVEVSEDIAEWDYGDYEGLRVGEVRSSRKERGLDRDQDWN-IWRHGyegGESAQQVTERLDRL 118
                 55668999*****************998888888899************************998887776666665.44445577************** PP

                 HHHHHHH CS
  His_Phos_1 130 leelaar 136
                 ++++++ 
  EEA18790.1 119 ISKIRDL 125
                 **99875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (153 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       468  (0.026103); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.41
# Mc/sec: 1114.07
//
Query:       EEA18791.1  [L=326]
Description: ribosomal small subunit assembly protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.8e-30  105.9   0.0    2.6e-30  105.4   0.0    1.2  1  RRM_Rrp7  Rrp7 RRM-like N-terminal domain
    2.1e-29  102.0   4.3    2.1e-29  102.0   4.3    1.8  2  RRP7      Ribosomal RNA-processing protein 7 (RRP7) C-termina


Domain annotation for each model (and alignments):
>> RRM_Rrp7  Rrp7 RRM-like N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  105.4   0.0   2.9e-34   2.6e-30       1     160 [.      11     202 ..      11     204 .. 0.87

  Alignments for each domain:
  == domain 1  score: 105.4 bits;  conditional E-value: 2.9e-34
    RRM_Rrp7   1 eikGFlvlPlkLpks.kklknkatHYlylkkHqtknndeessrslFlvNlPiettletlkkffqkvalgatiesvvsslltdeqedvsidltkltsdle 98 
                 ei+G++vlP+kLp++ ++ ++ +tHY+yl++H+++ +d++  rslFlvN+Pi tt  +l++ f  +  ++++e v    ++ +++ +  + t  t+ ++
  EEA18791.1  11 EISGYTVLPIKLPPAlPSFPELVTHYVYLRPHEPRIPDPDAARSLFLVNVPIDTTELHLRHLFSSQLSAGRVERV---QFEGVFRSSTSNTTATTAVIK 106
                 699*********987367788******************************************************...999999999999999999999 PP

    RRM_Rrp7  99 lkdeekdeeeakl.............................PkntglvkfvDkssvelafnalkKlsksstkke..Weldk...keplgsqrfln 160
                  +++e+++ +++                                 +++v+fvD++++e++++a++K++++++k+   W  ++     +lg +r+++
  EEA18791.1 107 ADTSETQQGKKRKrqdvitsaeletqlrsagfpstwdrelhpSGSHAIVTFVDRPAMEASLKAVRKYAAKEKKSPviWGEGIedrIATLGTTRYRK 202
                 84444443333335899999*********************55689*********************99988887789887755556677777766 PP

>> RRP7  Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.1      0.37   3.4e+03      62      71 ..     110     119 ..      87     125 .. 0.43
   2 !  102.0   4.3   2.4e-33   2.1e-29       2     115 ..     207     320 ..     206     324 .. 0.82

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.37
        RRP7  62 ekakkkekkk 71 
                 +++++ +k+k
  EEA18791.1 110 SETQQGKKRK 119
                 2222222222 PP

  == domain 2  score: 102.0 bits;  conditional E-value: 2.4e-33
        RRP7   2 ksrpseeelqeevdeymeefdkeeeeekkeekkkeeevDeDGfvtVtrgkkaaakeeaaeekakkkekkkkkkkell.dFYrFQirekkkeelaeLrkk 99 
                  ++p+ +el + v++ym+ +++ ee+ ++e++++++e+DeDGf+tVtrg + +     +ee+ k+  +k++k++e l dFYrFQ+rek+ke+++eL++k
  EEA18791.1 207 LRYPPADELLSIVNNYMSLYTQWEETCAAEASRRAAEPDEDGFITVTRGPRFTDVA--REEEVKELVEKQRKREEGLgDFYRFQTREKRKERQNELLRK 303
                 578999******************************************65443322..23444444444444444455********************* PP

        RRP7 100 FeeDkekieelkekr.k 115
                 F+eDk+kie+lk++r +
  EEA18791.1 304 FDEDKRKIEKLKKSRgR 320
                 **************955 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (326 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1260  (0.0702772); expected 358.6 (0.02)
Passed bias filter:                      602  (0.0335769); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.24s 00:00:00.75 Elapsed: 00:00:00.40
# Mc/sec: 2433.45
//
Query:       EEA18792.1  [L=337]
Description: meiotic recombination protein (Dmc1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   8.2e-112  372.6   0.0   1.1e-111  372.2   0.0    1.1  1  Rad51            Rad51
    3.7e-11   43.0   0.0    4.9e-11   42.6   0.0    1.1  1  RecA             recA bacterial DNA recombination protein
    3.3e-08   34.0   1.1    6.4e-08   33.1   0.3    1.9  2  HHH_5            Helix-hairpin-helix domain
    7.4e-07   28.8   0.0    1.6e-06   27.6   0.0    1.7  1  ATPase           KaiC
    1.2e-05   24.9   0.0    3.1e-05   23.6   0.0    1.6  2  AAA_25           AAA domain
     0.0035   17.1   0.0      0.015   15.0   0.0    2.0  1  AAA_24           AAA domain
  ------ inclusion threshold ------
      0.023   14.0   0.1       0.77    9.0   0.1    2.2  1  DnaB_C           DnaB-like helicase C terminal domain
        0.1   11.7   0.0        1.3    8.0   0.0    2.1  2  PAXNEB           PAXNEB protein
       0.12   11.6   0.0         11    5.1   0.0    2.2  2  Phage_HK97_TLTM  Tail length tape measure protein


Domain annotation for each model (and alignments):
>> Rad51  Rad51
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  372.2   0.0  5.3e-115  1.1e-111       2     254 ..      81     333 ..      80     334 .. 0.99

  Alignments for each domain:
  == domain 1  score: 372.2 bits;  conditional E-value: 5.3e-115
                 S-EBHHHHHHHHHSS-EE--S-HHHHHHHTSSEESSSEEEEEESTTSSHHHHHHHHHHHTTS-TTTS--SSEEEEEESSS---GGGGHHHHHHTT--HH CS
       Rad51   2 gfvsavellekrsellqlttGskklDelLgGGietgsiteifGefrsGktqlchtlcvtvqlplelgGgegkavyidtegtfrperlveiaerykldke 100
                 gf++a el ++r+++ +++tGsk++D++LgGG+++ si+e++Gefr+Gktql+ht++v++qlp+e+gGgegk++yidtegtfrp+r+ +iaery+ld e
  EEA18792.1  81 GFITAIELCHQRKKVFKISTGSKQFDTILGGGFQSSSISEVYGEFRCGKTQLSHTMSVIAQLPKEMGGGEGKVAYIDTEGTFRPDRIAQIAERYGLDAE 179
                 9************************************************************************************************** PP

                 HHGGGEEEEE--STTHHHHHHHHTHHHHHHS-EEEEEEETTTGGGCH-------THHHHHHHHHHHHHHHHHHHHH--EEEEEEE-------.------ CS
       Rad51 101 evlenvayaRaytiehqeellqqaaallaedkfallivDsvtalyRtdfsgrgelakRqqklgkllrtLrkladefevavvitnqvvaqvdgqaalfsa 199
                 ++ en++yaRa ++ehq ell+++++++a  +++ll++Ds+++++R+dfsgrgela+Rqqkl+++l +L++la+ef+v+v++tnqv+++++++a +  a
  EEA18792.1 180 STQENISYARALNSEHQLELLNTLSKEFAGGQYRLLVIDSIMNCFRVDFSGRGELAERQQKLNQFLIRLSHLAEEFNVCVLMTNQVQSDPGASALFAGA 278
                 ********************************************************************************************8888889 PP

                 ------HHHHHHHH-SEEEEEEE-STTEEEEEEES-SSS-S-EEEEEEETTEEE- CS
       Rad51 200 dpkkPigGlvlahasttRlalrkgkgeeRivkvvdsPnlpeleavfaigeeGied 254
                 d +kP+gG+vlahasttR+ lrkg+g+eR++k++dsP++pe+ea+++i++ Gi+d
  EEA18792.1 279 DGRKPVGGHVLAHASTTRVLLRKGRGDERVAKIQDSPDCPEREATYVITNGGIND 333
                 *****************************************************98 PP

>> RecA  recA bacterial DNA recombination protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.6   0.0   2.5e-14   4.9e-11      20     221 ..      86     301 ..      66     314 .. 0.74

  Alignments for each domain:
  == domain 1  score: 42.6 bits;  conditional E-value: 2.5e-14
                 --TTS--.-----EE--S-HHHHHHTSSSSEETTSEEEEEESTTSSHHHH..HHHHHHHHHHT....T--EEEEESS----H....HHHHHTT--GG.. CS
        RecA  20 mklgdekeklkvetissGslaldialGiGGlpkGriieiyGpessGkttl..alhaiaeaqkk....ggvaafidaehaldp....kyakklGvdid.. 106
                 ++l +  +++kv  is+Gs ++d+ lG GG+    i e+yG    Gkt l  ++++ia+  k+     g +a+id+e ++ p    + a++ G+d +  
  EEA18792.1  86 IELCH--QRKKVFKISTGSKQFDTILG-GGFQSSSISEVYGEFRCGKTQLshTMSVIAQLPKEmgggEGKVAYIDTEGTFRPdriaQIAERYGLDAEst 181
                 44544..45899***************.********************99445899***998743223689********9983333468899**97522 PP

                 ..G-EEE--SSHHHHHHHHHHHHT...TT--SEEEEE-TTT---STT---..--------HHHHHHHHHHHHHHHHHTTT--EEEEEEE-------..- CS
        RecA 107 ..ellvsqpdtGeqaleiadalvr...sgaidlivvdsvaalvpkaeieG..emgdskvglqarlmsqalrkltgaisksntvvifinqirekiGv..m 196
                   ++  ++  + e+ le++++l +    g   l+v+ds+     + +  G  e+++     q + + q l +l+   ++ n+ v++ nq++   G   +
  EEA18792.1 182 qeNISYARALNSEHQLELLNTLSKefaGGQYRLLVIDSIMNCF-RVDFSGrgELAER----Q-QKLNQFLIRLSHLAEEFNVCVLMTNQVQSDPGAsaL 274
                 22677788999***********8733257799******98754.5555540044443....3.34578899999999*************998775223 PP

                 --..-------HHHHHHH-SEEEEEEE CS
        RecA 197 fg..npetttGGralkfyasvrldvrr 221
                 f   +     GG+ l   ++ r+ +r+
  EEA18792.1 275 FAgaDGRKPVGGHVLAHASTTRVLLRK 301
                 441234455688888888888877776 PP

>> HHH_5  Helix-hairpin-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.1   0.3   3.2e-11   6.4e-08       5      57 .]      22      74 ..      18      74 .. 0.94
   2 ?   -3.1   0.0       6.3   1.3e+04      29      51 ..     289     311 ..     289     313 .. 0.74

  Alignments for each domain:
  == domain 1  score: 33.1 bits;  conditional E-value: 3.2e-11
                HTSTT--HHHHHHHHTTT--SHHHHHHS-HHHHHTSTTS-HHHHHHHHHHHHH CS
       HHH_5  5 lsvsGiGpktAlallsaGiesvedlaaadveeLakipGiGkktAeriilelkd 57
                ++  GiG++++++l  +G+++v+ +  a++ +L ki+G+++ ++e+i++++++
  EEA18792.1 22 IEAHGIGAADVIKLKAHGYFTVASVHGATRRTLLKIKGFSEIKVEKIKDAIQK 74
                5668********************************************99876 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 6.3
                 HHHS-HHHHHTSTTS-HHHHHHH CS
       HHH_5  29 laaadveeLakipGiGkktAeri 51 
                 la+a++ ++   +G G +++ +i
  EEA18792.1 289 LAHASTTRVLLRKGRGDERVAKI 311
                 67778888777788888888777 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.6   0.0     8e-10   1.6e-06       1     191 [.      98     303 ..      98     332 .. 0.76

  Alignments for each domain:
  == domain 1  score: 27.6 bits;  conditional E-value: 8e-10
      ATPase   1 vktgIeglDeilkgGipegrvvlitGepGtGKtifalqF.likgaek.y...gepgvfvtveepa..edlrenakslGwdlekleeegklaiidasesa 92 
                 ++tg + +D+il gG+ + ++  ++Ge  +GKt ++ +  +i ++ k +   + ++ ++ +e +     + + a++ G d e  +e+  + +  a +s+
  EEA18792.1  98 ISTGSKQFDTILGGGFQSSSISEVYGEFRCGKTQLSHTMsVIAQLPKeMgggEGKVAYIDTEGTFrpDRIAQIAERYGLDAESTQEN--ISYARALNSE 194
                 579********************************9886344554331322135899*****976559*****************99..7777776665 PP

      ATPase  93 eesaeekdkedleelieelaeaikeikakrvviDsitgl.a........yeekeavaReilrqlvrvlkklgvTailvsekss............seea 170
                 +            el+++l +  +  + + +viDsi +             e+++++ + l +l +  ++ +v  +++++++s            + + 
  EEA18792.1 195 H----------QLELLNTLSKEFAGGQYRLLVIDSIMNCfRvdfsgrgeLAERQQKLNQFLIRLSHLAEEFNVCVLMTNQVQSdpgasalfagadGRKP 283
                 4..........4689999******************876322222222245778889999999999999***********9998877777777766677 PP

      ATPase 171 aggygveefivdgvivLdlke 191
                 +gg+ +++ +++  + L++ +
  EEA18792.1 284 VGGHVLAH-ASTTRVLLRKGR 303
                 77777777.666666666544 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       1.6   3.2e+03     158     177 ..       5      24 ..       2      30 .. 0.78
   2 !   23.6   0.0   1.6e-08   3.1e-05      33     189 ..     116     265 ..      98     270 .. 0.75

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 1.6
      AAA_25 158 densnsdvgalvealeriar 177
                 +  ++sdv+ ++ ++++i++
  EEA18792.1   5 EVSDDSDVDDFIIDIDNIEA 24 
                 5678999*******999943 PP

  == domain 2  score: 23.6 bits;  conditional E-value: 1.6e-08
      AAA_25  33 gelallaGapgtGKttlaldlalavatGkpwlgpvapeqgkVlyvsaEdsedelrrRlravgealrddarllvldlagveslpLfakdrggtlltadvd 131
                  +++ ++G   +GKt l   +++   + k    ++    gkV y+++E++    + R++++ e + +da+ +  ++        +a+ ++++l  + ++
  EEA18792.1 116 SSISEVYGEFRCGKTQLSHTMSVIAQLPK----EMGGGEGKVAYIDTEGTF--RPDRIAQIAERYGLDAESTQENISYA-----RALNSEHQL--ELLN 201
                 56667889999999988776666555544....555699***********8..79999999999944444433333222.....122344444..6677 PP

      AAA_25 132 aleaaieevegvrlvviDplsralggdensnsd.......vgalvealeriarrtgaavllvhHv 189
                  l ++     ++rl+viD++  +++ d     +        ++++ +l ++a+++++ vl++ +v
  EEA18792.1 202 TLSKEFAG-GQYRLLVIDSIMNCFRVDFSGRGElaerqqkLNQFLIRLSHLAEEFNVCVLMTNQV 265
                 88999888.88*************99777776666666666*******************99877 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   7.4e-06     0.015       7      77 ..     121     223 ..     119     270 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 7.4e-06
      AAA_24   7 iyGpsgiGKTtlakel.............gpkplfidtekGlksldadkfpdie........swedfldevvel..............aaeladyktlv 70 
                 +yG+   GKT l  ++             + k+++idte+      +d++ +i         s ++ ++++ +l              + +  +y+ lv
  EEA18792.1 121 VYGEFRCGKTQLSHTMsviaqlpkemgggEGKVAYIDTEG---TFRPDRIAQIAerygldaeSTQENISYARALnsehqlellntlskEFAGGQYRLLV 216
                 7****************************9**********...569999999999999988855555555555577777788888899899999***** PP

      AAA_24  71 iDtidel 77 
                 iD+i   
  EEA18792.1 217 IDSIMNC 223
                 ***9765 PP

>> DnaB_C  DnaB-like helicase C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.1   0.00039      0.77     127     179 ..     206     266 ..      97     271 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00039
                 H...TTEEEEEEEEGGGTB....TSCS...SSCCCHHHHHHHHHHHHHHHHCTSXEEEEEEXS CS
                 x...xxxxxxxxxxxxxxx....xxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      DnaB_C 127 e...kglgliviDyLqlme....gsee...kenreqevseisrsLkalakelnvpvialsqLs 179
                 e   ++ +l+viD +        +        +r+q++ +   +L +la e+nv v++  q++
  EEA18792.1 206 EfagGQYRLLVIDSIMNCFrvdfS--GrgeLAERQQKLNQFLIRLSHLAEEFNVCVLMTNQVQ 266
                 333477888999976543323331..13335599***********************999976 PP

>> PAXNEB  PAXNEB protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   0.0   0.00068       1.3      19      35 ..      98     114 ..      92     122 .. 0.87
   2 ?    1.5   0.0     0.065   1.3e+02     212     255 ..     216     262 ..     130     274 .. 0.74

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00068
      PAXNEB  19 tStGtpsLDklLgGGLp 35 
                 +StG++++D++LgGG+ 
  EEA18792.1  98 ISTGSKQFDTILGGGFQ 114
                 8**************96 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.065
      PAXNEB 212 vipsLlspllyd...yppeeskpedllkFLhsLrallrssnlvalit 255
                 vi s+++    d     + ++++++l +FL  L  l+ + n+++l+t
  EEA18792.1 216 VIDSIMNCFRVDfsgRGELAERQQKLNQFLIRLSHLAEEFNVCVLMT 262
                 55555555555544445567889999999999999999888888887 PP

>> Phage_HK97_TLTM  Tail length tape measure protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0    0.0098        19      94     117 ..      62      85 ..      46     106 .. 0.79
   2 ?    5.1   0.0    0.0057        11     172     269 ..     236     335 ..     221     337 .] 0.79

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.0098
  Phage_HK97_TLTM  94 eqkveelkkeldkyqvsingylvn 117
                      e kve++k++++k  ++ ng++  
       EEA18792.1  62 EIKVEKIKDAIQKCLPTANGFITA 85 
                      679******************964 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0057
  Phage_HK97_TLTM 172 aeqnkvkrsllilNeekaesnklldlgNkklae..tvkLleeikkveiPvrvkeaevnkkikdllkkseRdlelsklkge.akvireaefeAkD 262
                        q+k +++l+ l +  +e+n+ + + N++  +    +L     +   Pv           + ll+k + d  ++k+++  +   rea ++   
       EEA18792.1 236 ERQQKLNQFLIRLSHLAEEFNVCVLMTNQVQSDpgASAL-FAGADGRKPVGGHVLAHASTTRVLLRKGRGDERVAKIQDSpDCPEREATYVITN 328
                      468999999999999999***999999998876223444.555555556555555566667789***************999999********* PP

  Phage_HK97_TLTM 263 aGlnsdd 269
                      +G+n  d
       EEA18792.1 329 GGINDPD 335
                      **99665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (337 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       668  (0.0372581); expected 358.6 (0.02)
Passed bias filter:                      632  (0.0352502); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 2330.93
//
Query:       EEA18793.1  [L=246]
Description: zinc knuckle nucleic acid binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.7e-43  144.2  57.6    2.3e-07   30.6   0.9    7.2  7  zf-CCHC    Zinc knuckle
    1.6e-09   37.3  41.7       0.18   11.6   1.1    7.1  7  zf-CCHC_4  Zinc knuckle
     0.0014   18.4   1.0     0.0014   18.4   1.0    7.1  7  zf-CCHC_2  Zinc knuckle
     0.0016   18.4  46.5      0.012   15.5   0.5    6.9  5  zf-CCHC_3  Zinc knuckle
  ------ inclusion threshold ------
      0.013   15.2  44.7       0.02   14.6   0.9    7.1  7  zf-CCHC_5  GAG-polyprotein viral zinc-finger


Domain annotation for each model (and alignments):
>> zf-CCHC  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   2.5   1.3e-07   0.00047       1      17 [.       6      22 ..       6      23 .. 0.86
   2 !   19.8   2.2   1.7e-07    0.0006       2      17 ..      27      42 ..      26      43 .. 0.92
   3 !   23.7   2.3   9.3e-09   3.3e-05       2      17 ..      51      66 ..      50      67 .. 0.93
   4 !   26.0   1.8   1.7e-09   6.3e-06       2      17 ..      78      93 ..      77      94 .. 0.93
   5 !   28.7   2.6   2.5e-10   9.1e-07       2      17 ..     128     143 ..     127     144 .. 0.94
   6 !   30.6   0.9   6.5e-11   2.3e-07       2      17 ..     148     163 ..     147     164 .. 0.94
   7 !   30.5   1.1   6.9e-11   2.5e-07       2      17 ..     176     191 ..     175     192 .. 0.93

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 1.3e-07
                SCTSSSSSSSSTTTTST CS
     zf-CCHC  1 rkCynCGepGHiardCp 17
                r+Cy+CG++GH+a  C+
  EEA18793.1  6 RACYKCGNIGHYAEVCS 22
                58**********97775 PP

  == domain 2  score: 19.8 bits;  conditional E-value: 1.7e-07
                CTSSSSSSSSTTTTST CS
     zf-CCHC  2 kCynCGepGHiardCp 17
                 CynC +pGH ++ Cp
  EEA18793.1 27 LCYNCKQPGHESNACP 42
                6**************9 PP

  == domain 3  score: 23.7 bits;  conditional E-value: 9.3e-09
                CTSSSSSSSSTTTTST CS
     zf-CCHC  2 kCynCGepGHiardCp 17
                +Cy+C++ GH+  dCp
  EEA18793.1 51 QCYHCQGLGHVQADCP 66
                8**************9 PP

  == domain 4  score: 26.0 bits;  conditional E-value: 1.7e-09
                CTSSSSSSSSTTTTST CS
     zf-CCHC  2 kCynCGepGHiardCp 17
                 Cy CG+ GH+ r+Cp
  EEA18793.1 78 RCYSCGQAGHLVRNCP 93
                7**************9 PP

  == domain 5  score: 28.7 bits;  conditional E-value: 2.5e-10
                 CTSSSSSSSSTTTTST CS
     zf-CCHC   2 kCynCGepGHiardCp 17 
                 +Cy+CG+p H+ardC 
  EEA18793.1 128 TCYKCGGPNHFARDCQ 143
                 7**************5 PP

  == domain 6  score: 30.6 bits;  conditional E-value: 6.5e-11
                 CTSSSSSSSSTTTTST CS
     zf-CCHC   2 kCynCGepGHiardCp 17 
                 kCy CG+ GHi+rdC+
  EEA18793.1 148 KCYACGKLGHISRDCT 163
                 8**************8 PP

  == domain 7  score: 30.5 bits;  conditional E-value: 6.9e-11
                 CTSSSSSSSSTTTTST CS
     zf-CCHC   2 kCynCGepGHiardCp 17 
                 +Cy+C + GHi+rdCp
  EEA18793.1 176 VCYKCSQAGHISRDCP 191
                 8**************9 PP

>> zf-CCHC_4  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.6   1.1     5e-05      0.18      31      48 ..       5      22 ..       4      23 .. 0.92
   2 !   10.3   0.2   0.00012      0.44      32      48 ..      26      42 ..      25      43 .. 0.93
   3 !   10.6   0.9    0.0001      0.36      34      48 ..      52      66 ..      49      67 .. 0.91
   4 !   11.0   1.0   7.7e-05      0.28      34      48 ..      79      93 ..      76      94 .. 0.91
   5 ?    3.8   0.5     0.013        48      33      48 ..     128     143 ..     125     144 .. 0.90
   6 !   10.1   0.7   0.00014       0.5      33      48 ..     148     163 ..     146     164 .. 0.90
   7 !    7.2   0.4    0.0011       4.1      32      48 ..     175     191 ..     173     192 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 5e-05
   zf-CCHC_4 31 rsfCyiCgvlGHsdkrCd 48
                r++Cy Cg +GH ++ C+
  EEA18793.1  5 RRACYKCGNIGHYAEVCS 22
                689************997 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00012
   zf-CCHC_4 32 sfCyiCgvlGHsdkrCd 48
                ++Cy+C   GH+ ++C+
  EEA18793.1 26 RLCYNCKQPGHESNACP 42
                78**************8 PP

  == domain 3  score: 10.6 bits;  conditional E-value: 0.0001
   zf-CCHC_4 34 CyiCgvlGHsdkrCd 48
                Cy C  lGH+ ++C+
  EEA18793.1 52 CYHCQGLGHVQADCP 66
                **************8 PP

  == domain 4  score: 11.0 bits;  conditional E-value: 7.7e-05
   zf-CCHC_4 34 CyiCgvlGHsdkrCd 48
                Cy+Cg  GH +++C+
  EEA18793.1 79 CYSCGQAGHLVRNCP 93
                **************8 PP

  == domain 5  score: 3.8 bits;  conditional E-value: 0.013
   zf-CCHC_4  33 fCyiCgvlGHsdkrCd 48 
                  Cy Cg  +H +++C+
  EEA18793.1 128 TCYKCGGPNHFARDCQ 143
                 5**************7 PP

  == domain 6  score: 10.1 bits;  conditional E-value: 0.00014
   zf-CCHC_4  33 fCyiCgvlGHsdkrCd 48 
                 +Cy Cg lGH  ++C 
  EEA18793.1 148 KCYACGKLGHISRDCT 163
                 6**********99995 PP

  == domain 7  score: 7.2 bits;  conditional E-value: 0.0011
   zf-CCHC_4  32 sfCyiCgvlGHsdkrCd 48 
                 ++Cy C   GH  ++C+
  EEA18793.1 175 KVCYKCSQAGHISRDCP 191
                 68**************8 PP

>> zf-CCHC_2  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   2.2      0.18   6.5e+02       9      19 ..      11      21 ..       7      21 .. 0.83
   2 !    5.1   1.2    0.0059        21       6      14 ..      28      36 ..      27      43 .. 0.84
   3 ?   -1.7   1.0      0.74   2.6e+03      18      21 .]      64      67 ..      52      67 .. 0.83
   4 !   18.4   1.0   3.9e-07    0.0014       9      21 .]      82      94 ..      78      94 .. 0.90
   5 ?    1.3   2.0     0.085   3.1e+02       9      19 ..     132     142 ..     128     143 .. 0.90
   6 ?    2.0   2.3     0.053   1.9e+02       5      19 ..     148     162 ..     148     162 .. 0.83
   7 !    6.3   0.9    0.0024       8.7       6      21 .]     177     192 ..     176     192 .. 0.87

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.18
   zf-CCHC_2  9 CgkkGHyIqdC 19
                Cg+ GHy   C
  EEA18793.1 11 CGNIGHYAEVC 21
                9999***7766 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0059
   zf-CCHC_2  6 ChiCgkkGH 14
                C  C+++GH
  EEA18793.1 28 CYNCKQPGH 36
                889****** PP

  == domain 3  score: -1.7 bits;  conditional E-value: 0.74
   zf-CCHC_2 18 dCPt 21
                dCPt
  EEA18793.1 64 DCPT 67
                8997 PP

  == domain 4  score: 18.4 bits;  conditional E-value: 3.9e-07
   zf-CCHC_2  9 CgkkGHyIqdCPt 21
                Cg+ GH +++CPt
  EEA18793.1 82 CGQAGHLVRNCPT 94
                ************8 PP

  == domain 5  score: 1.3 bits;  conditional E-value: 0.085
   zf-CCHC_2   9 CgkkGHyIqdC 19 
                 Cg + H+ +dC
  EEA18793.1 132 CGGPNHFARDC 142
                 9********** PP

  == domain 6  score: 2.0 bits;  conditional E-value: 0.053
   zf-CCHC_2   5 vChiCgkkGHyIqdC 19 
                 +C +Cgk GH  +dC
  EEA18793.1 148 KCYACGKLGHISRDC 162
                 699*******66666 PP

  == domain 7  score: 6.3 bits;  conditional E-value: 0.0024
   zf-CCHC_2   6 ChiCgkkGHyIqdCPt 21 
                 C  C + GH  +dCPt
  EEA18793.1 177 CYKCSQAGHISRDCPT 192
                 666************8 PP

>> zf-CCHC_3  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -5.4  17.7         5   1.8e+04       4      24 ..       5      36 ..       3      75 .. 0.78
   2 !    6.6   0.7    0.0021       7.5       4      22 ..      76      94 ..      73     105 .. 0.81
   3 !    7.0   4.2    0.0016       5.9       5      28 ..     127     150 ..     124     151 .. 0.84
   4 !    4.9   0.4    0.0074        27       6      22 ..     148     164 ..     143     169 .. 0.81
   5 !   15.5   0.5   3.4e-06     0.012       2      27 ..     172     196 ..     171     209 .. 0.83

  Alignments for each domain:
  == domain 1  score: -5.4 bits;  conditional E-value: 5
   zf-CCHC_3  4 saaCQkClkkGHw..........tYECkn.ag 24
                + aC kC+  GH+           Y Ck+   
  EEA18793.1  5 RRACYKCGNIGHYaevcssaerlCYNCKQpGH 36
                67999999999997777777777777776422 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0021
   zf-CCHC_3  4 saaCQkClkkGHwtYECkn 22
                + +C  C++ GH+   C+ 
  EEA18793.1 76 GGRCYSCGQAGHLVRNCPT 94
                579**********888885 PP

  == domain 3  score: 7.0 bits;  conditional E-value: 0.0016
   zf-CCHC_3   5 aaCQkClkkGHwtYECknagerky 28 
                 a+C kC+++ H++  C++++ + y
  EEA18793.1 127 ATCYKCGGPNHFARDCQAQAMKCY 150
                 78***************8776655 PP

  == domain 4  score: 4.9 bits;  conditional E-value: 0.0074
   zf-CCHC_3   6 aCQkClkkGHwtYECkn 22 
                  C  C+k GH +  C++
  EEA18793.1 148 KCYACGKLGHISRDCTA 164
                 6889********99995 PP

  == domain 5  score: 15.5 bits;  conditional E-value: 3.4e-06
   zf-CCHC_3   2 nasaaCQkClkkGHwtYECknagerk 27 
                 +a+++C kC++ GH +  C+ ++e+k
  EEA18793.1 172 SAGKVCYKCSQAGHISRDCP-TNENK 196
                 6899****************.66664 PP

>> zf-CCHC_5  GAG-polyprotein viral zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.1     0.004        14       5      20 ..       8      23 ..       6      26 .. 0.93
   2 ?    1.0   1.6       0.1   3.6e+02       3      18 ..      26      41 ..      24      43 .. 0.84
   3 ?   -0.6   1.2      0.31   1.1e+03       5      18 ..      52      65 ..      49      67 .. 0.86
   4 ?    5.8   1.1    0.0031        11       3      18 ..      77      92 ..      75      94 .. 0.93
   5 ?   14.6   0.9   5.5e-06      0.02       5      22 ..     129     146 ..     125     148 .. 0.89
   6 ?   10.9   0.9   7.8e-05      0.28       5      31 ..     149     172 ..     145     175 .. 0.86
   7 ?    6.4   0.7    0.0021       7.4       4      18 ..     176     190 ..     173     196 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.004
                -TTT-SSBS-TTT--- CS
   zf-CCHC_5  5 CpRCkkgkHwardChs 20
                C +C+   H+a  C s
  EEA18793.1  8 CYKCGNIGHYAEVCSS 23
                9*************88 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.1
                -B-TTT-SSBS-TTT- CS
   zf-CCHC_5  3 glCpRCkkgkHwardC 18
                 lC  Ck+  H  + C
  EEA18793.1 26 RLCYNCKQPGHESNAC 41
                69*****999988887 PP

  == domain 3  score: -0.6 bits;  conditional E-value: 0.31
                -TTT-SSBS-TTT- CS
   zf-CCHC_5  5 CpRCkkgkHwardC 18
                C  C    H+  dC
  EEA18793.1 52 CYHCQGLGHVQADC 65
                88899889*****9 PP

  == domain 4  score: 5.8 bits;  conditional E-value: 0.0031
                -B-TTT-SSBS-TTT- CS
   zf-CCHC_5  3 glCpRCkkgkHwardC 18
                g+C  C++  H  r+C
  EEA18793.1 77 GRCYSCGQAGHLVRNC 92
                9*************** PP

  == domain 5  score: 14.6 bits;  conditional E-value: 5.5e-06
                 -TTT-SSBS-TTT---SE CS
   zf-CCHC_5   5 CpRCkkgkHwardChskf 22 
                 C +C+   H ardC++++
  EEA18793.1 129 CYKCGGPNHFARDCQAQA 146
                 ***************987 PP

  == domain 6  score: 10.9 bits;  conditional E-value: 7.8e-05
                 -TTT-SSBS-TTT---SEEGGGEE--- CS
   zf-CCHC_5   5 CpRCkkgkHwardChskfdknGnpLsa 31 
                 C  C+k  H  rdC +    nG pLs 
  EEA18793.1 149 CYACGKLGHISRDCTA---PNGGPLSS 172
                 999***********88...58888885 PP

  == domain 7  score: 6.4 bits;  conditional E-value: 0.0021
                 B-TTT-SSBS-TTT- CS
   zf-CCHC_5   4 lCpRCkkgkHwardC 18 
                  C +C +  H  rdC
  EEA18793.1 176 VCYKCSQAGHISRDC 190
                 5************** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (246 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1045  (0.0582855); expected 358.6 (0.02)
Passed bias filter:                      300  (0.0167327); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.47
# Mc/sec: 1570.96
//
Query:       EEA18794.1  [L=507]
Description: UDP-N-acetylglucosamine pyrophosphorylase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-60  204.0   0.0    4.5e-60  203.4   0.0    1.1  1  UDPGP     UTP--glucose-1-phosphate uridylyltransferase
  ------ inclusion threshold ------
       0.23   10.5   0.4       0.44    9.6   0.1    1.6  2  MMS22L_C  S-phase genomic integrity recombination mediator, C


Domain annotation for each model (and alignments):
>> UDPGP  UTP--glucose-1-phosphate uridylyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  203.4   0.0     5e-64   4.5e-60      36     372 ..     105     482 ..      76     501 .. 0.85

  Alignments for each domain:
  == domain 1  score: 203.4 bits;  conditional E-value: 5e-64
       UDPGP  36 dyedlkekeeekkell..nklavlkLnGglGtsmGckgpKslieVr..dgktfLdlivqqie......elnkkynvdvPlvlmnSfnTdedtekilk.. 122
                 d++dl++  +e  +l+  nk+av+ ++Gg+Gt++G + pK+ +++   ++k++++l++++i       e  ++ +  vP++ m+S  T++ te++++  
  EEA18794.1 105 DQKDLEKYYNEGLRLVseNKVAVVLMAGGQGTRLGSSAPKGCFDIGlpSHKSLFQLQAERIAkiqslaEKTHNKKAVVPWYVMTSGPTNKPTEEFFQqh 203
                 4556644444444444779**************************999************99888777777788899********************88 PP

       UDPGP 123 kykk.kkvdiltfnqsryPriskesllpvekkakkeekeewyPpGhGdlyesLknsglldkllaeGkeyiFvsniDN.lgatvDlkilnllvekkaefl 219
                 +y++ +k ++++f+q+ +P is++ ++ +e+kak     + +P+G+G++y++L +sg+ +++ ++G e+++ +++DN l++++D+ ++++ ++k+++ +
  EEA18794.1 204 NYFGlDKANVKFFQQGVLPCISNDGKILLESKAK----VAVAPDGNGGIYQALITSGVREDMQRRGVEHVHTYCVDNcLAKVADPVFIGFAATKDVDIA 298
                 89999*************************9996....89*********************************************************** PP

       UDPGP 220 mevtektradvkgGtlieyegklrlleiaqvpkehveefk....svkkfkifntnniwinlkalkrlv.eekelkleiivnk.ktld.egekviqleta 311
                  +v++k +a++ +G + +++gk +++e++++ ke  e +     ++ kf+  n  n + ++++l+++    ++l ++++++k   +d e+ + ++ e++
  EEA18794.1 299 TKVVRKRNATESVGLILQKNGKPDVVEYSEIDKETAEAKDpehpEMLKFRAANIVNHYYSFRFLETIEsWAHKLPHHVARKKiPCVDmESGDSLKPEKP 397
                 *******************************77665443311113445555566666********9994559**********9899977777******* PP

       UDPGP 312 vgaaiksF..........kkavginVpR.srflpvkttsd...........lLlvksdlysleegslvlnpkrs..fktvplvkL 372
                 +g+++++F          +k+ +i+V R ++f+p+k+++             ++++ ++++ ++g +v+ ++ +  ++  pl++ 
  EEA18794.1 398 NGIKLEQFvfdvfpltplEKFACIEVRReDEFSPLKNARGtgqddpdtsrqDIMLQGKRWVEQAGAVVVTESDNagVEVSPLISY 482
                 ****************************99*******998888899999998899999999999977766655412466677765 PP

>> MMS22L_C  S-phase genomic integrity recombination mediator, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.1   4.9e-05      0.44     286     337 ..       3      54 ..       1      65 [. 0.89
   2 ?   -2.7   0.0      0.27   2.4e+03     167     195 ..     345     374 ..     341     378 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 4.9e-05
    MMS22L_C 286 ellqlmvessqaksseeikeeltsvlrsfvekhlavytqqvFelLekvaeld 337
                 +l+q ++ + q k +e ++e   + l+++ +k+++ ++ +vF++ +++   +
  EEA18794.1   3 SLVQNIIDKIQGKGEETPREPSAEELQQLRQKYETANQGHVFKFYDELKSAE 54 
                 6899****************************************99986554 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 0.27
    MMS22L_C 167 lkqllrniiqqYlp.rflpasssagklvah 195
                 lk +  ni+++Y + rfl +++s +   +h
  EEA18794.1 345 LKFRAANIVNHYYSfRFLETIESWAHKLPH 374
                 666778888888765888888887666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (507 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       680  (0.0379274); expected 358.6 (0.02)
Passed bias filter:                      590  (0.0329076); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.31s 00:00:00.93 Elapsed: 00:00:00.47
# Mc/sec: 3220.20
//
Query:       EEA18795.1  [L=454]
Description: cyclophilin-type peptidyl-prolyl cis-trans isomerase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.4e-34  118.4   0.0      5e-34  117.9   0.0    1.3  1  Pro_isomerase  Cyclophilin type peptidyl-prolyl cis-trans iso
    1.9e-15   56.4   0.6    5.1e-15   55.0   0.0    2.1  3  RRM_1          RNA recognition motif. (a.k.a. RRM, RBD, or RN


Domain annotation for each model (and alignments):
>> Pro_isomerase  Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.9   0.0   5.6e-38     5e-34       2     156 ..       3     169 ..       2     171 .. 0.86

  Alignments for each domain:
  == domain 1  score: 117.9 bits;  conditional E-value: 5.6e-38
  Pro_isomerase   2 vdietsskGrivieLfadkaPktvenFlklvkegfYdgttFhRvikgfmvqgGdptgktsageqekkggesi.........raipdEitsklkh.k 87 
                    v +ets +G++vi+L  d aPk++enFlkl+k ++Y+ +  h v k+f  q+Gdp g +s   ++++gg si         ++++ +  ++lkh +
     EEA18795.1   3 VLLETS-LGDLVIDLLVDVAPKACENFLKLCKVKYYNFSPVHSVQKNFTFQTGDPIGPGS---ADSDGGSSIwgllkgpthKTFAVDMPTRLKHtE 94 
                    568996.**************************************************977...334455555666666777777777777999999 PP

  Pro_isomerase  88 rGalamartg....kepnsagsqFfItlkea.phldgkytvFGkVveGmdvvekiekvetde.erpkknvkivsa 156
                    rG+++ma       +++  agsqF +tl+++ ++ldgk ++FGkVveG+dv+eki+++  d+  rp k+++i+++
     EEA18795.1  95 RGTVSMATVPspkdPDERLAGSQFIVTLGDNlDYLDGKAAIFGKVVEGFDVLEKINEAFIDDnGRPLKDIRIRHT 169
                    9******8767756777789********87526************************8888889********986 PP

>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.1      0.84   7.6e+03       6      18 ..     207     219 ..     206     221 .. 0.85
   2 !   55.0   0.0   5.7e-19   5.1e-15       1      70 []     250     320 ..     250     320 .. 0.98
   3 ?   -2.7   0.0      0.62   5.5e+03      21      40 ..     346     366 ..     345     374 .. 0.67

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 0.84
                 ETTTSSHHHHHHH CS
       RRM_1   6 LppdvteeeLkel 18 
                 L +d++ee +++l
  EEA18795.1 207 LDEDMDEEAMEQL 219
                 7899999999987 PP

  == domain 2  score: 55.0 bits;  conditional E-value: 5.7e-19
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrelk 70 
                 lfV  L+p + +e+L+ +Fs fGpi s++++rd +tg s  +af+eFe++ d e+A  ++ g  +++++++
  EEA18795.1 250 LFVCKLNPVTQDEDLHLIFSRFGPILSCEVIRDkKTGDSLQYAFIEFENQKDCEQAYFKMEGVLIDDHRIH 320
                 7999**************************************************************99986 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 0.62
                 TTSCEEEEEEEEE.TTTSEEE CS
       RRM_1  21 kfGpiksiklvrd.etgkskg 40 
                 +fG+i+s++  r+ +t  ++g
  EEA18795.1 346 GFGGISSLERKRQyRTAEARG 366
                 688888888888875555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (454 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       648  (0.0361426); expected 358.6 (0.02)
Passed bias filter:                      341  (0.0190195); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.46
# Mc/sec: 2985.32
//
Query:       EEA18796.1  [L=369]
Description: cyclophilin-type peptidyl-prolyl cis-trans isomerase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-15   56.9   0.8    3.7e-15   55.5   0.0    2.2  3  RRM_1          RNA recognition motif. (a.k.a. RRM, RBD, or RN
    1.3e-15   58.0   0.0    2.2e-15   57.3   0.0    1.3  1  Pro_isomerase  Cyclophilin type peptidyl-prolyl cis-trans iso
  ------ inclusion threshold ------
       0.18   11.8   0.0       0.41   10.7   0.0    1.6  1  Nup35_RRM_2    Nup53/35/40-type RNA recognition motif


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.1      0.64   3.8e+03       6      18 ..     122     134 ..     120     137 .. 0.84
   2 !   55.5   0.0   6.2e-19   3.7e-15       1      70 []     165     235 ..     165     235 .. 0.98
   3 ?   -2.4   0.0      0.72   4.3e+03      21      40 ..     261     281 ..     260     289 .. 0.67

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 0.64
                 ETTTSSHHHHHHH CS
       RRM_1   6 LppdvteeeLkel 18 
                 L +d++ee +++l
  EEA18796.1 122 LDEDMDEEAMEQL 134
                 8899999999987 PP

  == domain 2  score: 55.5 bits;  conditional E-value: 6.2e-19
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrelk 70 
                 lfV  L+p + +e+L+ +Fs fGpi s++++rd +tg s  +af+eFe++ d e+A  ++ g  +++++++
  EEA18796.1 165 LFVCKLNPVTQDEDLHLIFSRFGPILSCEVIRDkKTGDSLQYAFIEFENQKDCEQAYFKMEGVLIDDHRIH 235
                 7999**************************************************************99986 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 0.72
                 TTSCEEEEEEEEE.TTTSEEE CS
       RRM_1  21 kfGpiksiklvrd.etgkskg 40 
                 +fG+i+s++  r+ +t  ++g
  EEA18796.1 261 GFGGISSLERKRQyRTAEARG 281
                 688898888888875555444 PP

>> Pro_isomerase  Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.3   0.0   3.7e-19   2.2e-15      84     156 ..       5      84 ..       2      86 .. 0.87

  Alignments for each domain:
  == domain 1  score: 57.3 bits;  conditional E-value: 3.7e-19
  Pro_isomerase  84 lkh.krGalamartg....kepnsagsqFfItlkea.phldgkytvFGkVveGmdvvekiekvetde.erpkknvkivsa 156
                    lkh +rG+++ma       +++  agsqF +tl+++ ++ldgk ++FGkVveG+dv+eki+++  d+  rp k+++i+++
     EEA18796.1   5 LKHtERGTVSMATVPspkdPDERLAGSQFIVTLGDNlDYLDGKAAIFGKVVEGFDVLEKINEAFIDDnGRPLKDIRIRHT 84 
                    688899******8767756777789********87526************************8888889********986 PP

>> Nup35_RRM_2  Nup53/35/40-type RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   6.9e-05      0.41      21      53 .]     183     221 ..     179     221 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 6.9e-05
  Nup35_RRM_2  21 FasfGeIvkhyvp......kevsvmyvkfesekdaekAL 53 
                  F  fG+I   +v       ++  +++++fe+ kd+e+A+
   EEA18796.1 183 FSRFGPILSCEVIrdkktgDSLQYAFIEFENQKDCEQAY 221
                  55688888866666677778899***************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (369 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       734  (0.0409393); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 2536.25
//
Query:       EEA18797.1  [L=236]
Description: hypothetical protein PMAA_010750 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        0.9    9.2   6.9        2.7    7.7   3.3    2.0  2  DUF5349   Family of unknown function (DUF5349)


Domain annotation for each model (and alignments):
>> DUF5349  Family of unknown function (DUF5349)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   3.3   0.00015       2.7     215     295 ..      42     122 ..      22     137 .. 0.73
   2 ?    3.3   0.3    0.0032        57     228     268 ..     135     180 ..     119     200 .. 0.76

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00015
     DUF5349 215 lPsssaassstsatssssnnslntnvstsaslsgdllddlpvaptasslvgdlsstetvsnlsasqallessaassslgls 295
                  P+   ++ss  +++++  +   t+ s+s+s + ++l+d+ v+ +++  +g+ +++++ s++  s+  +     + ++++s
  EEA18797.1  42 FPTGNITLSSEDLSANRLLPVPTTASSSSTSNTLTYLKDIDVTANGPPFMGGEEPGDMYSFGVRSSNSTRAKPIPATMPFS 122
                 46666666666677777777777777888888889********9999999************5555544444444444444 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.0032
     DUF5349 228 tssssnnslntnvstsaslsgdllddlpvaptasslvg.....dls 268
                   s+  n++++++ + ++++ d+ d lp++++a++  g     d++
  EEA18797.1 135 QKSEIVNPIQNVMMKYTAITDDTFDGLPITSSAFTRSGtagssDID 180
                 55677799999*********************99987755444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (236 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       251  (0.0139997); expected 358.6 (0.02)
Passed bias filter:                      205  (0.011434); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1663.86
//
Query:       EEA18798.1  [L=621]
Description: pogo transposable element, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.5e-24   85.0   0.0    9.1e-24   84.1   0.0    1.5  1  DDE_1         DDE superfamily endonuclease
      9e-09   35.2   0.3    3.1e-08   33.5   0.3    2.0  1  HTH_Tnp_Tc5   Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
      0.055   12.4   1.6      0.083   11.8   1.6    1.2  1  Amidase       Amidase


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.1   0.0   1.5e-27   9.1e-24       2     175 .]     193     368 ..     192     368 .. 0.89

  Alignments for each domain:
  == domain 1  score: 84.1 bits;  conditional E-value: 1.5e-27
       DDE_1   2 erltvllcanaagsekLkplvigkak..sprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrleaekrk..ilLlldssrshetvel.le 94 
                 +++ ++++++ a++  + p +i+ ak  +++ ++    ++++  + +  ++ +w+ ++++ +WL +vfdk ++++ ++   lL+ld+++sh t+ + + 
  EEA18798.1 193 REWITTIGCICANGTAISPALIYMAKsgNLQDSWLQDFDAEQHRCFFATSESGWTNNEVGFAWLvNVFDKETKSQASRgwRLLILDGHGSHVTMRFiEY 291
                 678999****************9665226888999999***********************************666652267**************999 PP

       DDE_1  95 selqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                 ++++ i l+++Pa+s+++lqPld+ ++s+l + Y +ql + +++  +        lt +d+++   ++w+  +++e+i saf
  EEA18798.1 292 CDKNRILLAIFPAHSTHTLQPLDVAIFSPLSTAYTEQL-RRFINDCQGFTR----LTKRDFFRLFWASWEaTFTSENILSAF 368
                 **********************************8765.556666655555....9**************99******9987 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.5   0.3   5.2e-12   3.1e-08       2      60 ..      59     108 ..      58     115 .. 0.91

  Alignments for each domain:
  == domain 1  score: 33.5 bits;  conditional E-value: 5.2e-12
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh 60 
                  +e+ + L++Wi+ql+erg p+t++++ + A+e+         + + ++k+W  r++k h
   EEA18798.1  59 KEQSRTLIKWINQLTERGLPPTNSMLENFAREI---------SGKEPGKNWASRWLKAH 108
                  68999****************************.........67889**********99 PP

>> Amidase  Amidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   1.6   1.4e-05     0.083     309     396 ..     498     589 ..     470     612 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 1.4e-05
                 ---SS-SCCCCCCCHHHHCCS-HHHHHHHHHHHHHCSCCCCCCCHHHHHHHHH.HHHHHHHHHCCC...BSEEEEESSSSS--BCCCCCHHH CS
     Amidase 309 erlsetkvlsellpksraellgeevkrrielgnyalsaeasskyylkaqkvrr.llrrefakafee...lDvllsPtaptpaprlgekdkti 396
                 +  + ++  +++  k+ +++l+++ k + +    ++ +e++++ +++a++ +r   ++e+ak+ +     Dvl++P+ap+ a+++  k+ ++
  EEA18798.1 498 KDEQAAQEQARKDDKKLQQELTKQAKEQEKAERAQIRQEKQEQRLQEATEKQRlKDEQELAKLAHLqlqNDVLATPSAPKRAKKQVSKQVKV 589
                 2333344445666667777777777777777777777777777777777666656667777765557778*************998887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (621 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3079  (0.171733); expected 358.6 (0.02)
Passed bias filter:                      871  (0.0485805); expected 358.6 (0.02)
Passed Vit filter:                       170  (0.00948185); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.87u 0.29s 00:00:01.15 Elapsed: 00:00:00.44
# Mc/sec: 4218.04
//
Query:       EEA18799.1  [L=1148]
Description: ER glycosyl hydrolase (Edem), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.1e-117  393.8   0.0   1.5e-117  393.3   0.0    1.2  1  Glyco_hydro_47  Glycosyl hydrolase family 47


Domain annotation for each model (and alignments):
>> Glyco_hydro_47  Glycosyl hydrolase family 47
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  393.3   0.0  8.4e-122  1.5e-117       1     457 [.      50     601 ..      50     602 .. 0.93

  Alignments for each domain:
  == domain 1  score: 393.3 bits;  conditional E-value: 8.4e-122
                     HHHHHHHHHHHHCTTSSEEETTTTEE.............E-SS.SS-CCHHHHHHHHHHC........CHHHHHHHHHHHHHHC--......... CS
  Glyco_hydro_47   1 afkhswegYkkyAwghDelrPlskkg.............rdtfgglgatlvDsLdtllim........glkeefeeaveavekkid......... 65 
                     +f+h++++Y kyA+++DelrPl++++             +d++g++++t++DsL+tl i+        ++++ fe+ v+ + + +          
      EEA18799.1  50 MFYHGYDNYIKYAFPEDELRPLTCGPltrdrdhperielNDVLGNYSLTMIDSLSTLGILassndtgsRAWSYFENSVQEIVRLYGdgsqgpegq 144
                     79**********************************************************88888888778888888877775554799999999 PP

                     ......--S.SS.EEEHHHHHHHHHHHHHHHHHHH..........................................S-HHHHHHHHHHHHHHHH CS
  Glyco_hydro_47  66 ......fdtsdskevsvFEttIRyLGGLlsaydls.........................................ekkedvllekAveladrLl 113
                           fd  ds +v+vFEt+IR LGGLlsa+ ++                                           ++ +ll+ A +ladrLl
      EEA18799.1 145 gerargFD-LDS-KVQVFETVIRGLGGLLSAHLFAvgdlpirgynpsteateyakawnksgfsasknskgivwsngFIYNGQLLRLARDLADRLL 237
                     99999999.688.89**********************************************************9999999*************** PP

                     GGGSSTTS---SEEETTT--EE-.STCGC.........................EEEHHHHCSSHHHHHHHHHHHT-CHHHHHHHCCHHHHHCHC CS
  Glyco_hydro_47 114 pAFdtpsglpvarvnlkkrkaskkerass.........................esvlAelgslslEftrLsqlTgdkkYedlaervtkaleelq 183
                     pAF+tp+glp++rvnl+ + +  ++++ s                         e+++A +gsl+lEft+Ls+lTgd +Yedla+r+++a++   
      EEA18799.1 238 PAFYTPTGLPYPRVNLRYGVTFYDNSPLSkgypgqktddrkkyttryqsrpevtETCSAGAGSLVLEFTTLSRLTGDGRYEDLAKRAFWAVWL-- 330
                     ****************6555555544444788999999999**********9988899**********************************9.. PP

                     C.HHHTTB-BSEEETTT--EESTEE-SSTTTHHHHHHHHHHHHHCTS--...........................HHHHHHHHHHHHHHHHH.T CS
  Glyco_hydro_47 184 ektklpglvpikidastgkfvaekislgargDSyYEYllKqylllggee...........................eqyrkmyeealdaikkhll 251
                     +  +  +l++  ida+tg++va  +++ga++DS++EY++K y+ll++ e                           e y +++++a daik+hl+
      EEA18799.1 331 R-RSEIDLIGAGIDAETGNWVAPFTGIGAGIDSFFEYAFKAYVLLSTGEppefdtgspwsimdnyfipleqahhspEFYLQVWQDAQDAIKHHLY 424
                     3.3489****************************************98899************************999***************99 PP

                     EEE-TTT..--EEE-EECTTCTS.EE-EEEGGGGHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHHHHTSTTS---SEEEE-SS.....S-ECTS CS
  Glyco_hydro_47 252 frpskkkeddllfvgevtsteegklspeidhLscFlgGllalgakllekeedlelAkkltegcvkayeatktglmPEifevkpcesaeecewnee 346
                     + + +++   + ++g+++  ++++++++id+Ls+F++G+l l+       +++e A++++   +++++++  + +PE+++v++            
      EEA18799.1 425 RGHGYQH--PHYVQGDLQ--TGATRAFWIDSLSAFYPGVLTLA-------GRIEEATEIHLLATALWTRF--SALPERWNVATG----------- 495
                     9999999..569999998..77899******************.......89******************..*********942........... PP

                     SSSEEE-.GGG--B----HHHHHHHHHHHHH--THHHHHHHHHHHHHHHHCEETTEE--ECETTSSS-EE-S-B-HHHHHTHHHHHHHHC-S-TT CS
  Glyco_hydro_47 347 kkdealkriedrkyllRPEaiESlfylYritgdekyrevgwemfealekatktesgysaledVtkeepekeDemeSFwlaEtlKYlYLlFsdedv 441
                         +++     +   RPE+iES++ylYr+t+d++y++vg++++++++++++t++g+++l+dV+  ++e +D+meSF+l+Et KY++LlF++++ 
      EEA18799.1 496 ----EID-NDLGWWGGRPEFIESTYYLYRATKDPWYLHVGEMVLRDIKRRCWTRCGWAGLQDVR--TGELQDRMESFFLGETAKYMFLLFDQDHP 583
                     ....223.346699**************************************************..9**************************** PP

                     T-..TTTEEE-TTS-EEE CS
  Glyco_hydro_47 442 ls..ldeyVfnTeAHplk 457
                     l+     +Vf+Te+Hpl 
      EEA18799.1 584 LNnlEAPFVFTTEGHPLI 601
                     **98889*********96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1148 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       345  (0.0192426); expected 358.6 (0.02)
Passed bias filter:                      303  (0.0169); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.77u 0.28s 00:00:01.05 Elapsed: 00:00:00.45
# Mc/sec: 7670.40
//
Query:       EEA18800.1  [L=298]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.1e-12   48.2   0.1    2.6e-12   46.9   0.1    1.6  1  Abhydrolase_1  alpha/beta hydrolase fold
    1.3e-09   37.7   0.1    1.1e-08   34.7   0.1    1.9  1  Hydrolase_4    Serine aminopeptidase, S33
  ------ inclusion threshold ------
      0.044   13.2   0.1          1    8.8   0.0    2.1  2  Peptidase_S9   Prolyl oligopeptidase family
       0.15   12.1   0.0       0.33   11.1   0.0    1.5  1  Abhydrolase_4  TAP-like protein


Domain annotation for each model (and alignments):
>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.9   0.1   5.9e-16   2.6e-12       2     256 ..      28     284 ..      27     285 .. 0.93

  Alignments for each domain:
  == domain 1  score: 46.9 bits;  conditional E-value: 5.9e-16
                    EEEEE-STTTCGGGGTTGHHHHHHHHTTSEEEEEEETTSTTSSSTTTGB.CHHSHHHHHHHHHHHHHHCTTSSEEEEEETHHHHHHHHHHHHHGGG CS
  Abhydrolase_1   2 vlvilhGlpgssdvwaerglapaLakdgfdvillDlrGvgySspapacinddygtasvaddldrildalgddkltlvGhSmGGmialayaaeyper 97 
                    +l+++hG p  +  + +  l++ +ak+g  vi++   G+g S++ +       + ++  +d++ +ld+l  +k  + G+S  G  ala aa+ p  
     EEA18800.1  28 PLIFIHGTPSAGIPEPN--LVSVCAKKGIKVIGFSRAGYGGSTRNKGR-----QVVDSVADVKSLLDHLHAKKCFVAGWSGEGPHALACAARLPG- 115
                    89********9999999..***************************98.....7899************************************99. PP

                    EEEEEEESE........CSSCCHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHHHHCCSCHHHHHHHHHHHHHHHCHHHCCHHHHHHHCHHHHHHH CS
  Abhydrolase_1  98 Vkalvllga........idpaaslieaqrqqaksfpdffdgyaadcarnpagplladelaaleqrhrlvdalkfpdkskrfpssgsdnasslatga 185
                    + a+++ ++        +d+ a  +e++    ++  +   + ++ c+  +   l++d  +  ++ + l+ a +++   +++++ g++    l  g 
     EEA18800.1 116 CLAVISFAGcapyniegLDWLAGQGEDNIEEFNKALEGESQLRQFCEGHRKEYLASDLDGVMQVMSTLLPACDNATLIQNRDTIGQNMVDALHEGL 211
                    99999999998899999999999999999999999999999999999999999999999999999888888888********************** PP

                    HHHHHHHHHCCHHHHHHHHHCTHHHHSEEEEEEETTCSSSCHHHHHHHHHCHTS..EEEEEEETCSSSHHHHS CS
  Abhydrolase_1 186 lksieqwpttdsaklllrlrelknvlaptlvisgtsDplvppkaledlaqllpk..krlvvisdagHlafleg 256
                     +s ++w ++d   l  +  el++v +p+l+++gt+D++vp  ++  l ++lp+  ++ + +++ gH+++++g
     EEA18800.1 212 RLSADGWIDDDIEMLKPWGFELSEVRVPVLLYQGTEDKMVPFAQGKWLSEHLPQdkVKPHLLEGHGHISIFDG 284
                    ***********999999999999*******************77777778889999*************9987 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.7   0.1   2.4e-12   1.1e-08      22     236 ..      44     282 ..      28     284 .. 0.79

  Alignments for each domain:
  == domain 1  score: 34.7 bits;  conditional E-value: 2.4e-12
  Hydrolase_4  22 elaeaLaaqGfavyalDhrGhGrsegkrghvpsfddyvdDlaafvekvkeehpelplfllGhSmGGliallyllrypdkvaglilsaPalkikakl.. 117
                  +l+   a++G++v+++   G+G s  ++g  +++ d v+D++++++++      +++f+ G S  G  al+ ++r p  + ++i +a    ++ +   
   EEA18800.1  44 NLVSVCAKKGIKVIGFSRAGYGGSTRNKG--RQVVDSVADVKSLLDHLH----AKKCFVAGWSGEGPHALACAARLPG-CLAVISFAGCAPYNIEGld 134
                  56677799****************88888..99***************9....568**********************.3344444444333322223 PP

  Hydrolase_4 118 ..........kappllklllkllgkllpklqv..............................snnlkadslsrdpevvaayeadplv.hgkitvr.ll 173
                            +             ++ + l+                                   +++ l ++++ + +   d l  + +++++ ++
   EEA18800.1 135 wlagqgedniE-------------EFNKALEGesqlrqfceghrkeylasdldgvmqvmstlLPACDNATLIQNRDTIGQNMVDALHeGLRLSADgWI 219
                  35555554331.............33333333333344455555566678888999999988777999*******************98899996377 PP

  Hydrolase_4 174 lelldamkrleeraakitlPllllhGeaDkvvdpeasrelyerlgskdktlklypglyHelln 236
                   + ++++k    + +++++P+ll++G++Dk v+ ++ + l e+l++++++ +l +g  H  ++
   EEA18800.1 220 DDDIEMLKPWGFELSEVRVPVLLYQGTEDKMVPFAQGKWLSEHLPQDKVKPHLLEGHGHISIF 282
                  889*****************************************************9997655 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0     0.023     1e+02      37      84 ..      67     112 ..      58     126 .. 0.72
   2 ?    8.8   0.0   0.00023         1     142     175 ..     236     269 ..     221     284 .. 0.79

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.023
                   SGGGGHHHHHHHHHHHHHHHHTTS--GGGEEEEEETHHHHHHHHHHHH CS
  Peptidase_S9  37 krklgqnefdDfiaaaealakegyvdserlaitGgSyGGyltgaalnq 84 
                   + +++ +++ D +a ++ l +     ++++++ G+S  G  ++a++++
    EEA18800.1  67 STRNKGRQVVDSVADVKSLLD--HLHAKKCFVAGWSGEGPHALACAAR 112
                   455666666666666666655..56679********988888887765 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.00023
                   ---EEEEEEETT-SSS-THHHHHHHHHHH--S-S CS
  Peptidase_S9 142 aypplLlihGlaDdrvppaealklvaaLqkkgkn 175
                   + +p+Ll +G++D+ vp+a++  l + L + +++
    EEA18800.1 236 VRVPVLLYQGTEDKMVPFAQGKWLSEHLPQDKVK 269
                   678*****************99988888764444 PP

>> Abhydrolase_4  TAP-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   7.5e-05      0.33      33      74 ..     236     277 ..     226     293 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 7.5e-05
  Abhydrolase_4  33 gaapvLllqnerDpaTPyegakklakalggavlvtvegeGHg 74 
                    + +pvLl q++ D ++P++++k l++ l++ ++     eGHg
     EEA18800.1 236 VRVPVLLYQGTEDKMVPFAQGKWLSEHLPQDKVKPHLLEGHG 277
                    458*************************98554444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (298 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       335  (0.0186848); expected 358.6 (0.02)
Passed bias filter:                      330  (0.0184059); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.56u 0.31s 00:00:00.87 Elapsed: 00:00:00.51
# Mc/sec: 1763.44
//
Query:       EEA18801.1  [L=547]
Description: amidase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-52  178.6   0.5    6.6e-51  173.7   0.5    2.6  1  Amidase   Amidase


Domain annotation for each model (and alignments):
>> Amidase  Amidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  173.7   0.5   3.7e-55   6.6e-51       1     266 [.      53     330 ..      53     511 .. 0.75

  Alignments for each domain:
  == domain 1  score: 173.7 bits;  conditional E-value: 3.7e-55
                 HHHHHHHHHHHHHHHHH--EEEEEHCCCCHHHHT---TTT......TTTT-EEEEETTB--T...TSB--TTSGGGTT-B-SS--HHHHHHHHTT-EEE CS
     Amidase   1 elveaflkrieavneklnalvtvfieealaqAakldkkrargkekgpLhGvPisvKDnidvk...gvpttaGskalenypaekDatvverLkkaGavil 96 
                 ++v+++++ i ++n  ln +v+ + + al+qA+kldk r++g+  g LhG+P+++KDni++    ++ t a+  al +++++++a +v++L kaGa+il
  EEA18801.1  53 DIVKEYYHSILSYNGYLN-AVYELAPGALEQAEKLDKMREQGQILGHLHGIPVLLKDNIATSpdlKMGTRASAVALVGSVPKTNASIVDKLTKAGAIIL 150
                 689***************.99999*************************************997788999999************************** PP

                 EEE--SGGG-SSSSTT-TT.....---BBTTCTCC...........B--SSSHHHHHHHHTTSSSCEEEEESSSTTHHHHHHCTSEEEE--TTSC--TT CS
     Amidase  97 gkTnmdefamgsstensvf.....gptrNPwdksr...........tpGGSSGGsAAavAaglvplaiGtDtGGSiRiPAsfcglvGlKPtygrvSrag 179
                 gkT+m+e a++      +      g+ +NP+ k             + GGSS+GsA+ vAagl+p++iGt+t G    PA    l+ lKPt g v+ +g
  EEA18801.1 151 GKTTMSEYAYVKGEGIRCGwstlaGQCNNPYVKGGddptdglgghsSTGGSSSGSAVSVAAGLAPISIGTETEGFLVEPATRAALYTLKPTLGIVPGDG 249
                 *********975433222233335*******9876666677788889**************************************************** PP

                 B--SSTTT-EEEEEESSHHHHHHHHHHHBS--TT-TTS----HHHHHHHHCTT---TT-EEEEEGGGCSS---CCHHHHHHHHHHHH CS
     Amidase 180 vvalessldvvGplarsvedlalllrvilgedpkdstssvipeesedlaeelkkslkglriGvvkedgvasldpevqravekalkaL 266
                 ++++++ ld++Gp+a+sv+dla ll vi+ e + +          ++ a + +++ k++ iG ++ d+ + +++e+ + v++a ++ 
  EEA18801.1 250 IIPISHRLDTAGPMAKSVHDLASLLTVIVDESKTNILEGG-----YASALSGAEAWKEFTIGTLSPDD-CLPSDEFIKPVDEATEEI 330
                 *****************************76655433333.....34555666677899999998888.466666666666665554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (547 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       398  (0.0221987); expected 358.6 (0.02)
Passed bias filter:                      384  (0.0214178); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.45
# Mc/sec: 3613.25
//
Query:       EEA18802.1  [L=264]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00019   22.0   0.0    0.00046   20.8   0.0    1.7  1  GGACT     Gamma-glutamyl cyclotransferase, AIG2-like
    0.00041   20.7   0.1      0.021   15.2   0.1    2.4  1  AIG2_2    AIG2-like family
     0.0068   16.8   0.5      0.016   15.6   0.2    1.8  2  GspH      Type II transport protein GspH


Domain annotation for each model (and alignments):
>> GGACT  Gamma-glutamyl cyclotransferase, AIG2-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8   0.0   7.6e-08   0.00046       1      94 [.      60     182 ..      60     224 .. 0.78

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 7.6e-08
                 EEESSTTSTTSCCCHHHHCSEC....EEEEEEEECCTBEEEE.ETTTEEEE........................TTSSE.EEEEEEEE-HHHHHHHHH CS
       GGACT   1 vFvYGtLkrgepnhqrlllgar....flesgpatlkgyrlydlggkypalv........................pgdgekVkGelyevddeelarLDe 71 
                 +F+YG+    +p  +rl +++      ++++ a+++++r    +++y +++                        ++++  V G lye+++e+   LD 
  EEA18802.1  60 YFAYGSNL--SPTQMRLRCEHDpetsGRPLAIARIDRWRWLICERGYANVIppkewrvgrqvshgemisvsstgmDEENDVVFGILYEMTPEDEYLLDG 156
                 7*******..999999988832333344577888999997765579**************************998777779****************** PP

                 CT.....TTTTSEEEEEEEEEC....TTS- CS
       GGACT  72 lE....peepseYereevkvev...ledge 94 
                 +E      + s+Y  + ++++v   +   +
  EEA18802.1 157 YEgvdhSAPASQYGDT-IPIAVrprE---Q 182
                 **99987778888888.888884322...2 PP

>> AIG2_2  AIG2-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.1   3.5e-06     0.021       2      25 ..     139     162 ..     138     255 .. 0.92

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 3.5e-06
      AIG2_2   2 VfGvlweidlenlkdLDkqEgved 25 
                 VfG+l+e+++e++  LD +Egv++
  EEA18802.1 139 VFGILYEMTPEDEYLLDGYEGVDH 162
                 9*********************86 PP

>> GspH  Type II transport protein GspH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.2   2.7e-06     0.016      39     102 ..      19      88 ..       6     131 .. 0.90
   2 ?   -2.8   0.0       1.4   8.6e+03      35      48 ..     199     211 ..     174     227 .. 0.53

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 2.7e-06
                 SSCCCCEETTTCSSEEEEEESSSSTTESSEC..TT--SCEEE-TTSSCB--EEEEEE...TTCTCCEE.E CS
        GspH  39 vdanangtldggedvlrrgaaldggdtltga..akgtpqitFnpsGgeltpgtltlc...tsasagrs.r 102
                 +d+ +n+  d +e++l+++++ +++ t +++  ++ +++i +++ G +l+p +++l+   +++++gr+ +
  EEA18802.1  19 EDSTTNRLSDHNETILQQQVTDKSNITNSQTllSSFRARIFYFAYGSNLSPTQMRLRcehDPETSGRPlA 88 
                 7999******************************************999999999776644448888444 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1.4
                 CEESSSCCCCEETT CS
        GspH  35 Wrvfvdanangtld 48 
                 W+v  ++ +n+++d
  EEA18802.1 199 WLVT-KETDNEEDD 211
                 5555.333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (264 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       606  (0.0338); expected 358.6 (0.02)
Passed bias filter:                      514  (0.0286686); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.40
# Mc/sec: 1967.94
//
Query:       EEA18803.1  [L=59]
Description: hypothetical protein PMAA_010810 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
       0.14   11.9   0.0       0.21   11.3   0.0    1.2  1  DNA_RNApol_7kD  DNA directed RNA polymerase, 7 kDa subunit


Domain annotation for each model (and alignments):
>> DNA_RNApol_7kD  DNA directed RNA polymerase, 7 kDa subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   1.2e-05      0.21      13      25 ..      21      33 ..      17      34 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 1.2e-05
                    -SSS----SSS-- CS
  DNA_RNApol_7kD 13 kkgdpiRCkeCGh 25
                    +++++i C++CG+
      EEA18803.1 21 SENESIECTNCGS 33
                    679*********6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (59 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       635  (0.0354175); expected 358.6 (0.02)
Passed bias filter:                      466  (0.0259914); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.24s 00:00:00.63 Elapsed: 00:00:00.41
# Mc/sec: 430.34
//
Query:       EEA18804.1  [L=211]
Description: adenine phosphoribosyltransferase 1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.8e-17   62.3   0.0    5.2e-17   61.8   0.0    1.1  1  Pribosyltran  Phosphoribosyl transferase domain
  ------ inclusion threshold ------
      0.016   14.6   0.0      0.023   14.2   0.0    1.2  1  UPRTase       Uracil phosphoribosyltransferase


Domain annotation for each model (and alignments):
>> Pribosyltran  Phosphoribosyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.8   0.0   5.8e-21   5.2e-17      13     123 ..      69     184 ..      62     196 .. 0.90

  Alignments for each domain:
  == domain 1  score: 61.8 bits;  conditional E-value: 5.8e-21
                   EEEEETTEEEEEE--GGGEEEEEEETTTHHHHHHHHHHSTT-EE-EEEEEE-TTT--EE...............EE----TTSEEEEE-SEESSSHH CS
  Pribosyltran  13 davarlaaeileeyngkpdvvvgiargGvpfakiladeLevplayvrkvkyrpdgseeaargssdes.......rlledpagkkVliVDDildtGgT 102
                   + +++l   ile+y +kpdv+vg + +G+ f++ la +L++ ++ vrk+ + p++  + +  + +e        ++ + ++g+kVl+VDDi++tGg+
    EEA18804.1  69 ALIRSLELHILETYHEKPDVIVGLDARGFLFGPSLALRLGAGFVPVRKRGKLPGPCVTES--FQKEYgqdffqmQADAVKKGQKVLVVDDIIATGGS 163
                   57889999999*****************************************99888775..55566789*************************** PP

                   HHHHHHHHHCC-BSEEEEEEE CS
  Pribosyltran 103 llaalelLkekgpeevriavl 123
                     aa +l+ + g + ++++ +
    EEA18804.1 164 AAAAGNLVTKLGGTLLGFVFI 184
                   ********9999988877765 PP

>> UPRTase  Uracil phosphoribosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   2.5e-06     0.023     120     148 ..     147     175 ..     124     186 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 2.5e-06
     UPRTase 120 aertvlllDpviaTGgsaaaaiqlLkerg 148
                 + ++vl++D +iaTGgsaaaa +l+++ g
  EEA18804.1 147 KGQKVLVVDDIIATGGSAAAAGNLVTKLG 175
                 5678****************988888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (211 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       448  (0.0249875); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 1523.11
//
Query:       EEA18805.1  [L=533]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (533 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       713  (0.039768); expected 358.6 (0.02)
Passed bias filter:                      598  (0.0333538); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.38
# Mc/sec: 4247.53
//
Query:       EEA18806.1  [L=127]
Description: L-PSP endoribonuclease family protein (Hmf1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.7e-37  128.1   0.1      2e-37  127.9   0.1    1.0  1  Ribonuc_L-PSP  Endoribonuclease L-PSP


Domain annotation for each model (and alignments):
>> Ribonuc_L-PSP  Endoribonuclease L-PSP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.9   0.1   1.1e-41     2e-37       3     120 ..      13     126 ..      11     127 .] 0.96

  Alignments for each domain:
  == domain 1  score: 127.9 bits;  conditional E-value: 1.1e-41
                    TSTTTSSS-BSEEEETTEEEEEEE-SB-TTTSCB..-SSHHHHHHHHHHHHHHHHHHTT--GGGEEEEEEEESSGGGHHHHHHHHHHHSSSSTS-- CS
  Ribonuc_L-PSP   3 aapaaaapYsqavkagnlvyvsGqlpldpetgelv.egdveeqtrqalenlkavLaaagaslsdvVkvtvFladiedfaevnevyaeafdelkeaP 97 
                    aap +a+pYs+a+ka++l++ sG +p d+ +g++   g+++e+t+ +++n++avLaaag+++ +vVkvtvFl+d+ dfa++ne y ++f+++   P
     EEA18806.1  13 AAP-PAGPYSHAIKAQGLIFASGCIPCDA-EGKILeVGTLQEKTALCIQNVRAVLAAAGSEITKVVKVTVFLTDMGDFADMNEEYSKHFSHK---P 103
                    566.9***********************5.9999889*****************************************************99...* PP

                    EEEEEE-SBSGGG-SEEEEEEEE CS
  Ribonuc_L-PSP  98 arsaveVaaLpkgakvEIeaiav 120
                    ars+v+V++Lpkg+ vEIe++a 
     EEA18806.1 104 ARSCVAVKQLPKGVPVEIEVVAL 126
                    *********************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (127 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.44
# Mc/sec: 862.06
//
Query:       EEA18807.1  [L=361]
Description: zinc-binding alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.2e-22   79.0   4.7    3.3e-22   78.4   4.7    1.3  1  ADH_N         Alcohol dehydrogenase GroES-like domain
    3.1e-21   75.7   0.0    5.4e-21   74.9   0.0    1.4  1  ADH_zinc_N    Zinc-binding dehydrogenase
    1.4e-09   39.1   0.0    2.5e-09   38.3   0.0    1.4  1  ADH_zinc_N_2  Zinc-binding dehydrogenase
     0.0027   17.1   0.1     0.0044   16.4   0.1    1.2  1  2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, 
     0.0053   16.1   0.0     0.0079   15.5   0.0    1.2  1  AlaDh_PNT_C   Alanine dehydrogenase/PNT, C-terminal domain
  ------ inclusion threshold ------
       0.18   11.6   0.0       0.43   10.4   0.0    1.6  1  DUF268        Caenorhabditis protein of unknown function, DUF


Domain annotation for each model (and alignments):
>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.4   4.7   1.1e-25   3.3e-22       2     109 .]      36     156 ..      35     156 .. 0.88

  Alignments for each domain:
  == domain 1  score: 78.4 bits;  conditional E-value: 1.1e-25
                 TEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS.--TT-EEEE-SEEE.-....SSSHHHHTT-GGG-TTBEETTTS.... CS
       ADH_N   2 gevlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkk.lkvGdrVvveplis.c....geCaaCkegeenlCeeakllgvs.... 90 
                 ++v ikv+ +giCgsDlh+l+   ++++++p+ +GHEivG+ + vg++ ++ +kvGdrV v ++ + c    g C++C +g+e++C ++ + +++    
  EEA18807.1  36 TDVDIKVTHCGICGSDLHTLRS-GWSPANYPCCVGHEIVGIAVRVGSKAQGgIKVGDRVGVGAQAEsClgrkGPCEECASGNERYCGKHWTGTYNgtfm 133
                 689******************9.69************************999*********8888768887788************5555555555565 PP

                 ....S-SSSBSEEEECGGGEEEE CS
       ADH_N  91 ....ldGgfaeyvvvpekklvkl 109
                       Gg+a y   p+++++k+
  EEA18807.1 134 nggkSYGGYALYNRSPAHFVIKI 156
                 567899**********9999986 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.9   0.0   1.8e-24   5.4e-21       1     129 [.     197     323 ..     197     324 .. 0.92

  Alignments for each domain:
  == domain 1  score: 74.9 bits;  conditional E-value: 1.8e-24
                 HHHHHHHHHHHHTT-.EEEEEESSHHHHHHHHHTTESEEEETTTCHHHHHHHHHTTTSSEEEEEESSC.SHHHHHHHHHCEEEEEEEEECSCTSSEEE. CS
  ADH_zinc_N   1 gvGlaavqlAkalGa.eviavdsseeklelakklGadevinykeadlverikeltggegvdvvfecvG.sgatleaalkllkpgGrlvvvGggkgeee. 96 
                 g+G++a+ +AkalGa +v+av+++++k+e a klGad +i +   d ++ +++    + +d+++  v  s+  l+++++llk gG++   G++++++  
  EEA18807.1 197 GLGHFAILFAKALGAdKVVAVSRKSNKREDALKLGADSYIAT---DDDKNWEKEY-SRSLDLIVSSVSsSKMPLSDYVSLLKVGGTFIQLGIPEDGSLa 291
                 89****************************************...7799999999.7899**9999995677799*****************5555545 PP

                 EEHHHHHHTT-EEEEE-SSCHHHHHHHHHHHHH CS
  ADH_zinc_N  97 fdlrnlllkeksilGsllgslreefkealdlla 129
                 +++r l+++  ++ Gsl gs +++++e+l+l+a
  EEA18807.1 292 IPARALIMRGAKLGGSLIGS-PSDLREMLQLAA 323
                 ********************.9********976 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.3   0.0   8.5e-13   2.5e-09       1     128 [.     230     352 ..     230     357 .. 0.84

  Alignments for each domain:
  == domain 1  score: 38.3 bits;  conditional E-value: 8.5e-13
                   TT-SEEEETT.STTHHHHH-TT-EEEEEES-H.HHHH.HHHHHHEEEEEEEEE--.--.S-EEE-CHHHCTTT-EEEE--GGG...-.-HHHHHHHH CS
  ADH_zinc_N_2   1 lGAdevidyr.tedfeaatggegvDvvldtvg.gealleaslkvlpggGrlvsig.gpplsaallkpakkrkgrsvkyeflfsmkasaqadileela 94 
                   lGAd  i  + ++++e++  +++ D+++ +v  ++  l++ +++l+ gG+++++g     s a++++a+  +g+++  +++     s + d l+e++
    EEA18807.1 230 LGADSYIATDdDKNWEKEY-SRSLDLIVSSVSsSKMPLSDYVSLLKVGGTFIQLGiPEDGSLAIPARALIMRGAKLGGSLIG----S-PSD-LREML 319
                   8******5555999*9777.678*********8666679999999999*******655588888888886666666666665....4.889.***** PP

                   HHHHHHH----EEEEEEGGGHHHHHHHHHSS--S CS
  ADH_zinc_N_2  95 alieeGklrpvvdrvfpleeaaeAhrylesgrar 128
                   +l ++++l+p v+ + p+++a++A++++  g+ar
    EEA18807.1 320 QLAADKQLKPWVE-ERPMKDANQAIQDMNDGKAR 352
                   ************9.69***************997 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.1   1.5e-06    0.0044      36      79 ..     187     231 ..     184     240 .. 0.87

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 1.5e-06
                   TSEEEEES-SHHHHHHHHHHHHTT-.EEEEESSSHHHHHCHHHHT CS
  2-Hacid_dh_C  36 gktvGiiGlGrIGqavakrlkafgm.kviaydrskkkeeeeeelg 79 
                   gk +G+iG+G +G+ ++  +ka+g+ kv+a++r+ +k+e++ +lg
    EEA18807.1 187 GKSIGVIGVGGLGHFAILFAKALGAdKVVAVSRKSNKREDALKLG 231
                   899**********************99*******99887555555 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   2.6e-06    0.0079      31     100 ..     190     260 ..     174     288 .. 0.82

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 2.6e-06
                  EEEESTSHHHHHHHHHHHHTT-.EEEEEESSHHHHHHHHHTTTCECEEHCHHHHHHHHHHHH-SEEEE--- CS
  AlaDh_PNT_C  31 vlviGgGvaGlqAiatakglga.kVtvlDvrparleqleslgakfvevlksqeellaeavkeadvvigtvl 100
                  + viG+G  G  Ai  ak+lga kV+++  +++++e   +lga    +   +++  +e  ++ d+++++v 
   EEA18807.1 190 IGVIGVGGLGHFAILFAKALGAdKVVAVSRKSNKREDALKLGADSYIATDDDKNWEKEYSRSLDLIVSSVS 260
                  56*******************945888899999999999999995544555555556667789****9986 PP

>> DUF268  Caenorhabditis protein of unknown function, DUF268
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   0.00014      0.43      18      85 ..     206     274 ..     190     282 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00014
      DUF268  18 alknGakkiltveynkleieeefkdrlssilpvefaknwk.kyaekfdfaasfssieksglgrygdpld 85 
                 a   Ga+k+++v +++ + e+  k    s   ++  knw+ +y++++d+++s  s  k+ l+ y   l 
  EEA18807.1 206 AKALGADKVVAVSRKSNKREDALKLGADSYIATDDDKNWEkEYSRSLDLIVSSVSSSKMPLSDYVSLLK 274
                 5567***********************************636**********99999999999987665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (361 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       485  (0.0270511); expected 358.6 (0.02)
Passed bias filter:                      386  (0.0215294); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2551.53
//
Query:       EEA18808.1  [L=133]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-10   41.0   0.5    1.9e-10   40.3   0.5    1.4  1  Cupin_2       Cupin domain
    5.5e-06   26.1   0.0    7.6e-06   25.6   0.0    1.2  1  Cupin_1       Cupin
    9.3e-05   22.4   0.2    0.00015   21.7   0.2    1.3  1  AraC_binding  AraC-like ligand binding domain
    0.00022   21.0   0.4    0.00028   20.7   0.4    1.2  1  Cupin_6       Cupin
    0.00069   19.3   0.1     0.0011   18.6   0.1    1.3  1  Cupin_3       Protein of unknown function (DUF861)
    0.00074   19.4   0.1     0.0012   18.8   0.1    1.3  1  Cupin_7       ChrR Cupin-like domain


Domain annotation for each model (and alignments):
>> Cupin_2  Cupin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.3   0.5   6.3e-14   1.9e-10       4      63 ..      45     104 ..      42     112 .. 0.86

  Alignments for each domain:
  == domain 1  score: 40.3 bits;  conditional E-value: 6.3e-14
                 EEETTEEEEEECSSSEEEEEEEEESEEEEE.ECTEEEEEETTEEEEE-TT-EEEEEE-SSS CS
     Cupin_2   4 elppGesapshrHpgedeffyVleGegelt.vdgeeveleaGdsvyfpagtpHrfrNtgde 63 
                 ++ p + + +h+H+g  +++ Vl+G g +   + e  +++aGd+v  pagt H+++ +   
  EEA18808.1  45 TFTPCARTHWHTHEGG-QVIRVLSGSGWVCdKGKEARRIKAGDTVWAPAGTTHWHGADDGS 104
                 6677778889*****9.*************88899********************987655 PP

>> Cupin_1  Cupin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.0   2.5e-09   7.6e-06      31     107 ..      37     105 ..      29     116 .. 0.87

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 2.5e-09
                 STEEEEEEEE.TTEEEEEEEESSS-EEEEEEESEEEEEEEETTSS.EEEEEEEETTEEEEE-TT-EEEEEEESSSSE CS
     Cupin_1  31 lgisaarvdlepgglllPhyhpnateiayvlqGegrvgfvvpgngnrdfhkklreGdvfvvPaglvhfqynsgdepa 107
                   +++a v ++p +    h+h    +++ vl G+g    v+ +    ++ +++++Gd+++ Pag  h++ +++  ++
  EEA18808.1  37 TSVVMANVTFTPCARTHWHTH-EGGQVIRVLSGSGW---VCDKG---KEARRIKAGDTVWAPAGTTHWHGADD-GSL 105
                 57899999999*99999999*.**************...99997...9*********************9995.444 PP

>> AraC_binding  AraC-like ligand binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.7   0.2     5e-08   0.00015      16      90 ..      52     127 ..      48     132 .. 0.82

  Alignments for each domain:
  == domain 1  score: 21.7 bits;  conditional E-value: 5e-08
                   EEEETT-SEEEEEEEEE-EEEEETTEE.EEE-TT-EEEE-TTS-EEEEE-TTSEEEEEEEEE---GGGGGGG---E CS
  AraC_binding  16 fpphvhdeyvihyvteGtgrlrlngrt.ydlgpGdlfLlppgepHdyesdsedgweyrwlyfegelleriledssi 90 
                   + +h+h+  +++ v++G+g++  +g++  ++++Gd ++ p g+ H   +d++   +++++++  +  +++  d ++
    EEA18808.1  52 THWHTHEGGQVIRVLSGSGWVCDKGKEaRRIKAGDTVWAPAGTTHWHGADDGSLMTHFVVGLGETVWHEAVSDEEY 127
                   568******************5555555*****************9999999888888888777666666666555 PP

>> Cupin_6  Cupin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.7   0.4   9.3e-08   0.00028      19      78 ..      43     103 ..      35     128 .. 0.75

  Alignments for each domain:
  == domain 1  score: 20.7 bits;  conditional E-value: 9.3e-08
     Cupin_6  19 rsaltapwslrf..paglalhvvlrGscwlidpasgepvrLsagdvvllpggephvladspg 78 
                  +++t+  + ++   +g +++ vl+Gs w+ d++ +e +r++agd v  p g++h+   + g
  EEA18808.1  43 NVTFTPCARTHWhtHEGGQVIRVLSGSGWVCDKG-KEARRIKAGDTVWAPAGTTHWHGADDG 103
                 4445544444443244599************555.799*****************9866665 PP

>> Cupin_3  Protein of unknown function (DUF861)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.1   3.6e-07    0.0011      18      61 ..      51      95 ..      35     111 .. 0.84

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 3.6e-07
                EEEECESS.EEEEEEEECEEEEEETTTEEEEEETTEEEEE-TTEE CS
     Cupin_3 18 kfrltyee.dEfcyileGevkvtpeggetvelraGDlvvlpkgls 61
                + +++  e  + + +l+G   v ++g e+++++aGD v  p+g++
  EEA18808.1 51 RTHWHTHEgGQVIRVLSGSGWVCDKGKEARRIKAGDTVWAPAGTT 95
                4677777777888***********99999**************95 PP

>> Cupin_7  ChrR Cupin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.1   3.9e-07    0.0012      14      85 ..      32     105 ..      21     111 .. 0.75

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 3.9e-07
                 EEEEESSSS-EEEEEEEE-TTEE---EE-TT-EEEEEEEEE.EE....ETTEEEETTEEEEE-TT-EE--EESS-EE CS
     Cupin_7  14 pLerdgeekaratslvryapgsafsahkHpggeeilVLeGv.fs....deegdypaGsylrnppgsshapvseeGct 85 
                  ++rd +    + + v + p ++ ++h+H+gg  i VL+G  +     +e+++ +aG+ + +p g++h   +++G +
  EEA18808.1  32 LINRDTSV---VMANVTFTPCARTHWHTHEGGQVIRVLSGSgWVcdkgKEARRIKAGDTVWAPAGTTHWHGADDGSL 105
                 44444444...66678999********************9655411113566779*************999988865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (133 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       288  (0.0160634); expected 358.6 (0.02)
Passed bias filter:                      232  (0.0129399); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.41u 0.30s 00:00:00.71 Elapsed: 00:00:00.44
# Mc/sec: 913.55
//
Query:       EEA18809.1  [L=342]
Description: alcohol dehydrogenase, zinc-containing [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.8e-30  104.2   0.6    8.4e-30  103.4   0.6    1.4  1  ADH_zinc_N     Zinc-binding dehydrogenase
    1.4e-10   42.3   0.0    2.4e-10   41.6   0.0    1.4  1  ADH_zinc_N_2   Zinc-binding dehydrogenase
    1.1e-05   25.3   0.0    6.2e-05   22.8   0.0    2.3  3  ADH_N          Alcohol dehydrogenase GroES-like domain
     0.0022   17.5   0.4     0.0032   16.9   0.4    1.2  1  adh_short      short chain dehydrogenase
     0.0046   16.3   0.8     0.0075   15.6   0.8    1.3  1  AlaDh_PNT_C    Alanine dehydrogenase/PNT, C-terminal domain
     0.0089   16.3   0.0      0.016   15.4   0.0    1.4  1  TrkA_N         TrkA-N domain
       0.01   15.4   0.6      0.015   14.9   0.6    1.2  1  adh_short_C2   Enoyl-(Acyl carrier protein) reductase
  ------ inclusion threshold ------
      0.049   14.3   0.1      0.089   13.5   0.1    1.5  1  Acyl-CoA_dh_N  Acyl-CoA dehydrogenase, N-terminal domain


Domain annotation for each model (and alignments):
>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.4   0.6   3.7e-33   8.4e-30       1     121 [.     153     278 ..     153     288 .. 0.92

  Alignments for each domain:
  == domain 1  score: 103.4 bits;  conditional E-value: 3.7e-33
                 HHHHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTESEEEETTTC.HHHHHHHHHT.......TTSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSC. CS
  ADH_zinc_N   1 gvGlaavqlAkalGaeviavdsseeklelakklGadevinykea.dlverikelt.......ggegvdvvfecvGsgatleaalkllkpgGrlvvvGg. 90 
                 gvGlaavq+AkalGa+via+ +seek + a+++Gad+v+ny+ + ++ e++k+l+       g+ gvdvv++ vG   +++++lk+++ + rl v+G+ 
  EEA18809.1 153 GVGLAAVQIAKALGATVIAATGSEEKGQVARRFGADYVVNYRADkNWPEQVKKLCkenrkgnGKAGVDVVYDPVG---MIDQSLKCVAWNARLLVIGFa 248
                 9****************************************88889***************9899**********...********************7 PP

                 TSSEEEEEHHHHHHTT-EEEEE-SSCHHHHH CS
  ADH_zinc_N  91 gkgeeefdlrnlllkeksilGsllgslreef 121
                  +  e++ l+++llk++si+G+++g++   f
  EEA18809.1 249 AGTIEKVALNRVLLKNVSIIGIHWGQY-MNF 278
                 666666*******************94.333 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.6   0.0   1.1e-13   2.4e-10       2     133 .]     186     333 ..     185     333 .. 0.73

  Alignments for each domain:
  == domain 1  score: 41.6 bits;  conditional E-value: 1.1e-13
                   T-SEEEETT.STTHH...........HHH-TT-EEEEEES-HHHHH.HHHHHHEEEEEEEEE--.--.......S-EEE-CHHHCTTT-EEEE--GG CS
  ADH_zinc_N_2   2 GAdevidyr.tedfe...........aatggegvDvvldtvggealleaslkvlpggGrlvsig.gpp......lsaallkpakkrkgrsvkyeflf 79 
                   GAd v++yr ++++            +  g++gvDvv+d vg   ++++slk+++ ++rl++ig +        + +++l   k+ +  ++++  ++
    EEA18809.1 186 GADYVVNYRaDKNWPeqvkklckenrKGNGKAGVDVVYDPVG---MIDQSLKCVAWNARLLVIGfA-AgtiekvALNRVLL--KNVSIIGIHWGQYM 276
                   9********8888889999**99986555569**********...77*******888***999944.33543321111111..11233444444444 PP

                   G...-.-HHHHHHHHHHHHHHH--..--EEEE.EEGGGHHHHHHHHHSS--SSEEEE CS
  ADH_zinc_N_2  80 smkasaqadileelaalieeGklr..pvvdrv.fpleeaaeAhrylesgrarGKiVl 133
                     ++     + + +++li++Gk++     d+   +le +++A+++l s+ + GK+V+
    EEA18809.1 277 NFERETVPVVWKGIFDLIDQGKFKstAFTDENfIGLESVPRALKALGSRGTWGKVVV 333
                   33332333346***********9943456788899*********************8 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8   0.0   2.8e-08   6.2e-05       2      61 ..      29      90 ..      28      98 .. 0.87
   2 ?   -0.6   0.0      0.55   1.2e+03      91     109 .]      92     110 ..      89     110 .. 0.87
   3 ?   -3.0   0.0         3   6.8e+03       3      43 ..     144     181 ..     141     187 .. 0.59

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 2.8e-08
                TEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEE..ESTT-CS--TT-EEEE CS
       ADH_N  2 gevlikvkaagiCgsDlhilkggkelevklplilGHEivGevee..vgpevkklkvGdrVvv 61
                ++ li++++ag +  D+  ++g+ + + ++p i G E++G + +  +  + +k+kvGdrV+ 
  EEA18809.1 29 DKYLIEIHSAGTNFFDILQIQGKYQHQPPFPWISGMEFAGSILAtpTSAGNHKFKVGDRVFG 90
                5679******************99999****************9333455666*******86 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.55
                 S-SSSBSEEEECGGGEEEE CS
       ADH_N  91 ldGgfaeyvvvpekklvkl 109
                  +G++a+++++pe++l+++
  EEA18809.1  92 SQGAYATHILAPEASLFPV 110
                 48***********999876 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 3
                 EEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEE CS
       ADH_N   3 evlikvkaagiCgsDlhilkggkelevklplilGHEivGev 43 
                 +vl+  +a g+    ++i+k    l +    + G E  G+v
  EEA18809.1 144 WVLVHAAAGGVGLAAVQIAKA---LGATVIAATGSEEKGQV 181
                 566666666666555555554...44444455566666655 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.4   1.4e-06    0.0032       2      87 ..     144     228 ..     143     242 .. 0.88

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 1.4e-06
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHH..SSESEEEE---S CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkkl..gkldvLvnNAGi 87 
                 +vlv  a++G+G+a ++   + Ga+v+++  seek  +va  +++  + ++ +++D +  e+v++l ++ +k     ++dv++  +G+
  EEA18809.1 144 WVLVHAAAGGVGLAAVQIAKALGATVIAATGSEEKG-QVARRFGA--DYVVNYRADKNWPEQVKKLCKENRKGNgkAGVDVVYDPVGM 228
                 79**************************99999999.99999998..5799******************9999855569999888888 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.8   3.4e-06    0.0075      35      91 ..     150     205 ..     118     209 .. 0.75

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 3.4e-06
                  STSHHHHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTTCECEEHCHHHHHHHHHHHH CS
  AlaDh_PNT_C  35 GgGvaGlqAiatakglgakVtvlDvrparleqleslgakfvevlksqeellaeavke 91 
                   +G +Gl+A+++ak+lga+V +   ++++ +  + +ga    v ++  ++  e+vk+
   EEA18809.1 150 AAGGVGLAAVQIAKALGATVIAATGSEEKGQVARRFGAD-YVVNYRADKNWPEQVKK 205
                  4799****************999888888777777*999.55667777777777765 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   7.2e-06     0.016      55     115 ..     134     192 ..     120     193 .. 0.90

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 7.2e-06
                 HHHTTGGGESEEEE-SSSHHHHHHHHHHHHHHTSSSEEEEEESSGGGHHHHHHHTTSEEEE CS
      TrkA_N  55 Leeagiekadaviaatgddeanilavllakelnpkkkiiaraqdpehaellkklgadvvis 115
                 + +a+++  ++v++ +    + ++av++ak l    ++ia + ++e+ +++++ gad+v++
  EEA18809.1 134 VTRANVQAGEWVLVHAAAGGVGLAAVQIAKALGA--TVIAATGSEEKGQVARRFGADYVVN 192
                 6789999999999999999999********8666..6**********************97 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.6   6.6e-06     0.015       2      82 ..     150     231 ..     149     241 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 6.6e-06
                   TTTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSE.E..EE--TTSHHHHHHHHHHHHHHH..SSEEEEEE-----EG CS
  adh_short_C2   2 aasgIGraiAkalaeeGaevvltdlneeakkrveelaeelgae.v..lecDVtdeeqvealveevvekf..gklDilvnnagiapk 82 
                   aa g+G a+++ +++ Ga+v+++  +ee+     ++a+++ga+ v  +++D + +eqv++l +e ++     ++D++   +g+ ++
    EEA18809.1 150 AAGGVGLAAVQIAKALGATVIAATGSEEK----GQVARRFGADyVvnYRADKNWPEQVKKLCKENRKGNgkAGVDVVYDPVGMIDQ 231
                   569*********************99999....78999999997469*****************9999934458999988888877 PP

>> Acyl-CoA_dh_N  Acyl-CoA dehydrogenase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.1     4e-05     0.089      31     101 ..     107     178 ..      89     207 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 4e-05
                    SGHHHH.HHHHHHTTCTSTTS-GGGTS--S-.HHHHHHHHHHHHHH-HHHHH.HHHHHHHTTHHHHHHHS-HHH CS
  Acyl-CoA_dh_N  31 efprel.wkklaelGllgitvpeeygGagld.yleaaivaeelaradaglal.llgvhsslvapailrfGteeq 101
                     fp  + w  + ++Gl+ +t p+ ygG+    +++a  ++   a+a+ + +l ++++  +l+a +i++ G+ee 
     EEA18809.1 107 LFPVPRgWSFADAAGLF-VTAPTSYGGLVTRaNVQAGEWVLVHAAAGGV-GLaAVQIAKALGATVIAATGSEEK 178
                    46644557778889997.9********8632255555555544444443.33389999**************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       376  (0.0209716); expected 358.6 (0.02)
Passed bias filter:                      303  (0.0169); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2332.45
//
Query:       EEA18810.1  [L=472]
Description: hypothetical protein PMAA_010880 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.6e-13   48.7   1.4    1.6e-12   47.4   1.4    1.7  1  Clr5      Clr5 domain


Domain annotation for each model (and alignments):
>> Clr5  Clr5 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.4   1.4   8.9e-17   1.6e-12       2      54 .]       7      58 ..       6      58 .. 0.95

  Alignments for each domain:
  == domain 1  score: 47.4 bits;  conditional E-value: 8.9e-17
        Clr5  2 eedWeahkatIrrLYleenrsLkdvmeiMeeehgFkatkrqyktrfkkWgfrk 54
                +  We++ka+I rLY +e+++Lk+v++ +++e +F+++++q+++r+kkW+++k
  EEA18810.1  7 SDVWEKKKALIARLYKDEEWPLKQVIKQIRTE-DFNPSETQLRSRLKKWRVTK 58
                567**************************997.9****************988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (472 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1144  (0.0638072); expected 358.6 (0.02)
Passed bias filter:                      385  (0.0214736); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.24s 00:00:00.75 Elapsed: 00:00:00.39
# Mc/sec: 3642.39
//
Query:       EEA18811.1  [L=296]
Description: hypothetical protein PMAA_010890 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.2e-05   23.5   0.7    4.1e-05   22.6   0.7    1.3  1  Fungal_trans_2  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.6   0.7   2.3e-09   4.1e-05      17     103 ..       5      88 ..       2      93 .. 0.87

  Alignments for each domain:
  == domain 1  score: 22.6 bits;  conditional E-value: 2.3e-09
  Fungal_trans_2  17 vpessnpfrkvllplalsnkallhallalsafhlqskgpkds.lereakrykslalkelqealaelsstlsrnekykdiLaaiLllcs 103
                        + + ++ ++ +l   ++ +l+ +lalsa+hl++++p+d  +   ++r+  +al + + al++ s   s    ++++  +  +lc+
      EEA18811.1   5 NGAPAEAWQHTIPQLGFVSEVVLNPMLALSALHLHAHSPNDAmVGIAMQRFFGRALAHHRYALSDTSLSGS----SEQLWLSAVILCH 88 
                     5556778999999999999**********************99999*********************9999....6666666677776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (296 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       351  (0.0195772); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.25s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2111.92
//
Query:       EEA18812.1  [L=310]
Description: hscarg dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.4e-50  170.4   0.0    5.4e-50  170.1   0.0    1.0  1  NmrA             NmrA-like family
      3e-12   46.8   0.0      4e-12   46.4   0.0    1.2  1  NAD_binding_10   NAD(P)H-binding
    2.6e-05   23.4   0.0    3.5e-05   23.0   0.0    1.1  1  3Beta_HSD        3-beta hydroxysteroid dehydrogenase/isomeras
  ------ inclusion threshold ------
      0.052   14.3   0.0      0.089   13.5   0.0    1.4  1  DXP_reductoisom  1-deoxy-D-xylulose 5-phosphate reductoisomer
      0.084   12.9   0.0       0.16   12.1   0.0    1.4  1  Fer2_4           2Fe-2S iron-sulfur cluster binding domain
       0.15   12.5   0.1       0.51   10.8   0.0    1.9  2  Semialdhyde_dh   Semialdehyde dehydrogenase, NAD binding doma


Domain annotation for each model (and alignments):
>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  170.1   0.0   1.8e-53   5.4e-50       2     233 .]       6     246 ..       5     246 .. 0.93

  Alignments for each domain:
  == domain 1  score: 170.1 bits;  conditional E-value: 1.8e-53
                 EESSTTSHHHHHHHHHHHH.....HT-EEEEEES-S-SHHHHHHHHSTTEEEES-TT-HHHHHHHHTT-SEEEE---GG......S-HHHHHHHHHHHH CS
        NmrA   2 lviGaTGrqGksvvrallk.....aghkvralvRdtkselakslkeaGvelvkgdlddkeslvealkgvdvvfsvtgfy......skeiedgkklvdAa 89 
                 +v+GaTG qG+s+++++l+     +++++ra++R+++se++++lk++ ve+v++d+ d  s+++al g+++vf++t         + e   gk+++dAa
  EEA18812.1   6 AVFGATGVQGGSLIDYVLNdpelsQKYQIRAITRNVNSEKIAQLKNK-VEVVQADVSDPVSIDTALMGAHTVFAMTVPSftpdglEVEFSHGKTIADAA 103
                 8*****************999999********************987.***************************986678**999************* PP

                 HHHS-SEEEEEE---GG.GT.SSS---TTTHHHHHHHHHHHHCTS-EEEEEE-EEGGG-BSSS-SS-BEEE-TTS.-EEEEESS-TTS-EE..-HHHHH CS
        NmrA  90 keaGvkhfiySslgddndrsnaeepavphfdsKaeieeyvralgipytfvyagffmenflsllaqlkvgdtappedkvtllgpgnpkavll..daeeDi 186
                 ++ Gv+ +i+S+l+  n++s +++ +v+ fd+Ka+ie+y+r l i+  fv  gffm+n+ + +     g    p d+++l +p+     ++  da++++
  EEA18812.1 104 VRQGVEYLIFSTLPGVNEISGGKYSHVTPFDAKAKIEHYIRDLPIRNAFVSLGFFMQNLHTQPFL---GPVPAPDDTWVLARPAPRTSTIPyiDAVANV 199
                 ***********************************************************995444...6666666788888877655555556****** PP

                 HHHHHHHHHHHHHHTTEEEEE-SEEE-HHHHHHHHHHHHTS-EEEEE CS
        NmrA 187 GafvikilkdprklkgkriklagntlsgneivelfekkigktvkYtq 233
                 G++v +il +p+k++gk    a+  +s+ ei++l+++  gktv Y+q
  EEA18812.1 200 GNVVGSILAEPEKYEGKTFCAAERLYSLGEIAALLSRSSGKTVVYKQ 246
                 *********************************************86 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.4   0.0   1.4e-15     4e-12       1     146 [.       9     158 ..       9     177 .. 0.81

  Alignments for each domain:
  == domain 1  score: 46.4 bits;  conditional E-value: 1.4e-15
                     TTTSHHHHHHHHHHHHC-....T-EEEEEETT..HHHCHHHHCTTTCEEEE--TT-CCHHHHHHTT-SEEEES---TCC....HHHH....HHHH CS
  NAD_binding_10   1 GAtGkvGrllvkellarg....ghevtalvRn..peklaeleaeeglevvegdvtdvedlaealkgadaVvsalggggk....deeg....akni 81 
                     GAtG  G  l++  l++     +++++a++Rn  +ek+a+l+  +++evv++dv+d+ ++  al ga +V++ + ++ +    +  +     k+i
      EEA18812.1   9 GATGVQGGSLIDYVLNDPelsqKYQIRAITRNvnSEKIAQLK--NKVEVVQADVSDPVSIDTALMGAHTVFAMTVPSFTpdglE--VefshGKTI 99 
                     9***************9999999********86689999996..7*****************************6655533332..145779*** PP

                     HHHHHHCT--EEEEEEETTTTSGCGCHHHHHHHHCCHHHHHHHHHHHHHHHHSSSEEEEEEE-CE CS
  NAD_binding_10  82 vdaakeagvkRfvlvsaigvgdevpgefgewnkellkaylaakraaeellrasgldwTivrpggL 146
                     +daa ++gv+ +++ +  gv++ + g+ + +      + ++ak++ e+++r+  +   +v+ g++
      EEA18812.1 100 ADAAVRQGVEYLIFSTLPGVNEISGGKYSHV------TPFDAKAKIEHYIRDLPIRNAFVSLGFF 158
                     ********************96444444443......3467788888888776666666666655 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.0   0.0   1.2e-08   3.5e-05       1     114 [.       6     114 ..       6     128 .. 0.78

  Alignments for each domain:
  == domain 1  score: 23.0 bits;  conditional E-value: 1.2e-08
   3Beta_HSD   1 vvtGgaGFlGralvkeLvrlee...lkevrvlDlrespelleelskvnvkkviegDvtdkdkleealegvdvvihlaslvdvagkltedeimkvnvkGT 96 
                 +v G++G  G +l+  +++  e   + ++r++  + ++e+   + k +v+ v+++Dv d  +++ al g++ v+ +     v + +t d   +v     
  EEA18812.1   6 AVFGATGVQGGSLIDYVLNDPElsqKYQIRAITRNVNSEKIA-QLKNKVE-VVQADVSDPVSIDTALMGAHTVFAM----TVPS-FTPD-GLEVEFSHG 96 
                 589*************99876632256788777666666532.2333344.9*********************999....4444.4456.589***999 PP

   3Beta_HSD  97 rnvleacvkagvrvlvYt 114
                 +++ +a+v++gv++l++ 
  EEA18812.1  97 KTIADAAVRQGVEYLIFS 114
                 ****************95 PP

>> DXP_reductoisom  1-deoxy-D-xylulose 5-phosphate reductoisomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0     3e-05     0.089       1      56 [.       5      63 ..       5      88 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 3e-05
                     EEEESTTSHHHHHHHHHHHHCTT...TEEEEEEEESSTHHHHHHHHHHHT-SEEEESSH CS
  DXP_reductoisom  1 vviLGsTGSIGtqtLdvieenpd...kfevvalaagsnvellaeqakefkpklvavade 56
                     ++++G+TG  G + +d + + p+   k+++ a++ + n e++a++ +++++  + v+d 
       EEA18812.1  5 LAVFGATGVQGGSLIDYVLNDPElsqKYQIRAITRNVNSEKIAQLKNKVEVVQADVSDP 63
                     589*************99988544449******************99999887777775 PP

>> Fer2_4  2Fe-2S iron-sulfur cluster binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   5.2e-05      0.16       5      31 ..      83     109 ..      80     124 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 5.2e-05
      Fer2_4   5 tltfDGkevtvpeGdtvasAllangvd 31 
                 ++t DG ev+  +G+t+a+A+ ++gv+
  EEA18812.1  83 SFTPDGLEVEFSHGKTIADAAVRQGVE 109
                 6999*********************97 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00017      0.51       3      73 ..       6      72 ..       4     105 .. 0.63
   2 ?   -1.5   0.0       1.1   3.2e+03      11      64 ..     199     252 ..     195     260 .. 0.58

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00017
                    EEETTTSHHHHHHHHHHHCTSSEEEEEEEESTT..TTTSBHHHHSGGGTTTECEBEEEGGGGGCTT-SEEEE- CS
  Semialdhyde_dh  3 aivGatGyvGqellrlLeehpevelvvllsssr..saGkklaeavkaleegkdlkvedvdeeelkevdivfla 73
                    a+ GatG  G  l+ ++ ++pe++  + +       + +k+a++++      +++v ++d  +  ++d +++ 
      EEA18812.1  6 AVFGATGVQGGSLIDYVLNDPELSQKYQIRAITrnVNSEKIAQLKN------KVEVVQADVSDPVSIDTALMG 72
                    89********************988775433331123344444422......333333333334445555554 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1.1
                     HHHHHHHHHHCTSSEEEEEEEESTT..TTTSBHHHHSGGGTTTECEBEEEGGGGGC CS
  Semialdhyde_dh  11 vGqellrlLeehpevelvvllsssr..saGkklaeavkaleegkdlkvedvdeeel 64 
                     vG ++  +L+e  ++e  ++++ +r  s G+  a +  + ++gk++++++v+ ee+
      EEA18812.1 199 VGNVVGSILAEPEKYEGKTFCAAERlySLGEIAALL--SRSSGKTVVYKQVTLEEF 252
                     666667777776666666666666555555544444..235556666666555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (310 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       602  (0.0335769); expected 358.6 (0.02)
Passed bias filter:                      586  (0.0326845); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.47
# Mc/sec: 1994.99
//
Query:       EEA18813.1  [L=1644]
Description: SNF2 family helicase/ATPase (Swr1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    7.2e-66  222.3   0.7    1.4e-65  221.4   0.7    1.4  1  SNF2_N      SNF2 family N-terminal domain
    4.9e-20   71.9   0.0    1.8e-19   70.1   0.1    2.0  2  Helicase_C  Helicase conserved C-terminal domain
    2.1e-09   37.6   0.0    5.5e-09   36.2   0.0    1.8  1  ResIII      Type III restriction enzyme, res subunit
    4.6e-08   33.3  10.1    4.6e-08   33.3  10.1    3.0  3  HSA         HSA
    0.00046   20.0   0.0     0.0016   18.2   0.0    1.9  1  DEAD        DEAD/DEAH box helicase
  ------ inclusion threshold ------
        1.1   10.3   3.8         33    5.5   0.1    3.2  2  SMAP        Small acidic protein family


Domain annotation for each model (and alignments):
>> SNF2_N  SNF2 family N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  221.4   0.7   4.5e-69   1.4e-65      52     349 ..     803    1088 ..     798    1089 .. 0.85

  Alignments for each domain:
  == domain 1  score: 221.4 bits;  conditional E-value: 4.5e-69
                  HHTT--EEE---TTS--HHHHHHHHH...HHTTTS---.......S-EEEE--HHHHHHHHHHHHHH-TTS-EEE--SSHHHH-------------- CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      SNF2_N   52 kqsvrGGiLaDemGLGKTvqvlalilaqrakeekdkekkrkdtlagptLivvPaslldqWeneierhvsssalrvlvyggqkkmkkkntkvapklla 148 
                  + ++ +GiLaDemGLGKT+q++al++++            ++++ gp+L+vvP+s++ +We e+++++++ ++  +++++++++ k+      +   
  EEA18813.1  803 YTNHINGILADEMGLGKTIQTIALLAHLAV----------EHEVWGPHLVVVPTSVILNWEMEFKKWCPGFKIMTYYGNQEERKAKR---RGWTDDS 886 
                  67889*********************4443..........234568**************************977777666533333...3344456 PP

                  ---EEEE-HHHHHHHT......TTS-S-S-SEEEES-GGGT--TTSHHHHHHHH---S-EEEE-S--SSS-HHHHHHHHHHH-T........TTT-- CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxx RF
      SNF2_N  149 dydvvittYdvlsreaelqkkrsvlkqvewkrvvlDEghtlknstskaaeavskLstsnrwiltGTPiqnsledlygLlkfLre........epfge 237 
                    dv+it+Y+ + +++      +vlk++ w+++vlDE+h++kn  s+  +a+++++t+ r++ltGTP+qn+l++l++Ll fL++        e f +
  EEA18813.1  887 SWDVLITSYQLVLQDQ------QVLKRRAWHYMVLDEAHNIKNFRSQRWQALLTFRTRARLLLTGTPLQNNLTELWSLLFFLMPsdedgagvEGFAD 977 
                  789**********898......9***********************************************************873332222257999 PP

                  HHHHHHHTHHHHH...........HHHHHHHHHHHTT-STTEE---GGGT--S---EEEEEEEEE--HHHHHHHH....................HH CS
                  xxxxxxxxxxxxx...........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      SNF2_N  238 kqtfdkllqrpie...........aqaekgrsrLlqllqrlmlrrakkdveknlPpkteeiiflklskverksYnrllevlrkkalakllkrseaal 323 
                   + f++++ rp+e           ++a++ +++L+++l++++lrr k+dvek++P k e+++ ++lsk +r +Y   ++ + +            + 
  EEA18813.1  978 LRNFSEWFRRPVEqilehgretmdEEAKQIVHKLHTVLRPYLLRRLKADVEKQMPAKYEHVVTCRLSKRQRYLYDGFMSRAQT------------KE 1062
                  99*********************999*************************************************32222222............22 PP

                  HHHH-HHH-HHHHHHHHHHHHH---X CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxx RF
      SNF2_N  324 kssskskekilelllelrqacnhpql 349 
                  + +s +   i+++l++lr++cnhp+l
  EEA18813.1 1063 TLASGNYLSIINCLMQLRKVCNHPDL 1088
                  2222112459**************98 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       4.2   1.2e+04      20      71 ..     841     892 ..     825     894 .. 0.59
   2 !   70.1   0.1   5.9e-23   1.8e-19       2     111 .]    1337    1449 ..    1336    1449 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 4.2
                 EEEESSHHHHHHHHHHHHHT...TSTEEEESTTSTHHHHHHHHHHHHTTSSS.EEE CS
  Helicase_C  20 lifvntidrlekvklllekk...gikvavlhgelpqnereeileqfnkgesd.vLi 71 
                 l++v+t   l+    +  kk   g+k+ +++g  +q+er++  + + +++s  vLi
  EEA18813.1 841 LVVVPTSVILNWEMEF--KKwcpGFKIMTYYG--NQEERKAKRRGWTDDSSWdVLI 892
                 5555555544322222..23456999999999..7888887766666433333666 PP

  == domain 2  score: 70.1 bits;  conditional E-value: 5.9e-23
                  HHHHHHHHH.HHTTTTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSS..EEEESGGGTSSSTSTTESEEEESSSSS CS
  Helicase_C    2 kleallell.kleeeggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfnkgesd..vLiatdvaerGidipkvnlVinfdlpr 95  
                  kl++l +ll +l++ g+++lif++ +++l+ ++ +l+ +g ++++l+g+++ ++r+   ++fn++++   ++++t+ ++ Gi+++++++Vi++dl++
  EEA18813.1 1337 KLQQLDKLLrELQAGGHRALIFTQMTKMLDILEQFLNIHGHRYLRLDGTTKVEQRQMLTDRFNNDNRIlaFILSTRSGGLGINLTGADCVIFYDLDW 1433
                  788899999999*****************9888888888***********************9544433799************************* PP

                  SHHHHHHHHTTSSSTT CS
  Helicase_C   96 nvtsyiqriGRtgRag 111 
                  n++  +q  +R++R+g
  EEA18813.1 1434 NPAMDKQCQDRCHRIG 1449
                  **************97 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2   0.0   1.9e-12   5.5e-09       3     169 ..     787     947 ..     785     949 .. 0.80

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 1.9e-12
                 EE-HHHHHHHHHHT......TTSEEEEEESTTSTHHHHHHHHHHHH-S......-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--.... CS
      ResIII   3 elreyQeeaienlleklkskrdkrglikmaTGtGKTlvaaklierllkkgkee.kflflvprkslleqtleefkkflseaykeigkkvsgdkkka.... 96 
                 +lreyQ   ++ l+  l  +++ +g+++ + G GKT+  ++l ++l+ +++     l++vp+  ++  ++ efkk+ +  +  i++ + ++++++    
  EEA18813.1 787 TLREYQHYGLDWLA-GLY-TNHINGILADEMGLGKTIQTIALLAHLAVEHEVWgPHLVVVPTS-VILNWEMEFKKWCPGFK--IMTYYGNQEERKakrr 880
                 58899988887666.554.7999****************999999998755547899999986.55579******999864..4444444444444444 PP

                 .......-SEEEEEHHHHHHTH........HHHTTT-SEEEEETGGGTTS...TTTHHHHHT---SEEEEEESS- CS
      ResIII  97 kekdstnkkilvttiqsldadseeeeeeseellrdrfdviiiDEaHrlgak..kswreilekfkeavllglTATp 169
                    d++++++l+t++q + +d+       + l+r +  +++ DEaH+++    + w+++l  f+   +l lT+Tp
  EEA18813.1 881 GWTDDSSWDVLITSYQLVLQDQ-------QVLKRRAWHYMVLDEAHNIKNFrsQRWQALL-TFRTRARLLLTGTP 947
                 557899*************999.......89999999**********9987546999965.5588999999***9 PP

>> HSA  HSA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.3  10.1   1.5e-11   4.6e-08       2      67 ..     333     397 ..     332     402 .. 0.89
   2 ?   -1.1   1.1      0.85   2.5e+03       5      32 ..     429     454 ..     425     457 .. 0.79
   3 ?   -3.4   0.1       4.4   1.3e+04      17      31 ..     990    1004 ..     989    1009 .. 0.75

  Alignments for each domain:
  == domain 1  score: 33.3 bits;  conditional E-value: 1.5e-11
                 XXXXXXXX--HHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHHHHH--XXXXXXXXXXXXXXXXX CS
         HSA   2 qeperrqkthhdylLeeilwhakdfkeerkskrakakklaravakyhnniekeeqkriereekerl 67 
                  ep+  q +hhd+l++++l ++k + +e++++r+ a+++a+++a  ++++ k+ +   +++  e +
  EEA18813.1 333 EEPPI-QYSHHDHLVAHALFFRKLLDQEHRRHRNTARQFAHWCAEAWRKKHKRPEDILREQVEETK 397
                 35555.************************************************999987777655 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.85
                 XXXXX--HHHHHHHTTHHHHHHHHHHHH CS
         HSA   5 errqkthhdylLeeilwhakdfkeerks 32 
                 e  +k+ +++ L++++  ++ + e r++
  EEA18813.1 429 E--RKAENQQALNQAIKQSTMLFEKRRQ 454
                 3..6999999999999999999988887 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 4.4
                  HHTTHHHHHHHHHHH CS
         HSA   17 eeilwhakdfkeerk 31  
                  e+il+h+++  +e  
  EEA18813.1  990 EQILEHGRETMDEEA 1004
                  899999999776655 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0   5.5e-07    0.0016      18     142 ..     810     929 ..     798     952 .. 0.74

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 5.5e-07
                 EEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHH...HTTCSEEEEEHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxx RF
        DEAD  18 lvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskl...dngvdivvgtpgrlddlls 113
                 ++a e G GKT   + ++l++++  +++     l+v+Pt  +  +   ++kk++     +++  +g++++r+ +++    d++ d++++  + +++  +
  EEA18813.1 810 ILADEMGLGKTIQTI-ALLAHLAV-EHEVWGPHLVVVPTSVI-LNWEMEFKKWCPG--FKIMTYYGNQEERKAKRRGwtdDSSWDVLITSYQLVLQ--D 901
                 667789*****9855.55545544.34444467888998765.5677899999997..5666678877776666655554466*******998888..7 PP

                 CTSSHCTTEEEEEEETHHHHHHTTTHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD 114 tgklnlsqvrflVlDEadrlldqgfsdfi 142
                 ++ l+ +   ++VlDEa+++ +  +s+ +
  EEA18813.1 902 QQVLKRRAWHYMVLDEAHNIKNF-RSQRW 929
                 7889999************9987.44433 PP

>> SMAP  Small acidic protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.1     0.011        33      38      65 ..     384     417 ..     347     423 .. 0.65
   2 ?    3.8   0.8     0.037   1.1e+02      33      75 .]    1541    1583 ..    1497    1583 .. 0.74

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.011
        SMAP  38 a......anvaadvqkrqrlfsnLeqqYeaAraa 65 
                 +      ++v++++ kr+++ ++L++q++  ra+
  EEA18813.1 384 RpedilrEQVEETKAKRRQVIRDLQKQFDLVRAE 417
                 13456777899*****************987774 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.037
        SMAP   33 gagggaanvaadvqkrqrlfsnLeqqYeaAraathtmrgvGLG 75  
                  ++ ++++  +a +++++++++  + ++e+A  + +tm g+G G
  EEA18813.1 1541 EQVEDKEDIDAAKNAQKEMEHADDGDFEEAGTTAQTMSGAGTG 1583
                  3333335778888899999999999*******889*****976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1644 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1404  (0.0783089); expected 358.6 (0.02)
Passed bias filter:                      526  (0.0293379); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.03u 0.30s 00:00:01.33 Elapsed: 00:00:00.46
# Mc/sec: 10739.66
//
Query:       EEA18814.1  [L=155]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.2e-10   39.5   0.0    5.8e-10   39.3   0.0    1.2  1  NDUF_B8   NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASH


Domain annotation for each model (and alignments):
>> NDUF_B8  NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.3   0.0   3.2e-14   5.8e-10      49      96 ..      34      81 ..      17     134 .. 0.84

  Alignments for each domain:
  == domain 1  score: 39.3 bits;  conditional E-value: 3.2e-14
     NDUF_B8 49 kpyddDglgaGDYPklpvvsaderDPyedWddrdlrrnwGelvhldld 96
                ++ ddD    G+YP+ p v  + rDP  dW d+++rrn+Ge+vh d d
  EEA18814.1 34 QAEDDDPHLNGNYPNPPAVKRQFRDPNADWWDKQERRNFGEPVHEDND 81
                56678888************************************9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (155 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       378  (0.0210832); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.29s 00:00:00.70 Elapsed: 00:00:00.44
# Mc/sec: 1059.14
//
Query:       EEA18815.1  [L=1357]
Description: C2 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.3e-19   70.8   0.6    7.2e-10   39.2   0.4    2.9  2  Membr_traf_MHD  Munc13 (mammalian uncoordinated) homology dom
    5.8e-13   49.0   0.0    1.2e-12   48.0   0.0    1.5  1  C2              C2 domain
    3.9e-08   32.3   1.0    2.1e-06   26.6   0.2    2.7  3  DUF810          Plant family of unknown function (DUF810)


Domain annotation for each model (and alignments):
>> Membr_traf_MHD  Munc13 (mammalian uncoordinated) homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.2   0.4   1.2e-13   7.2e-10       2      53 ..    1110    1161 ..    1109    1164 .. 0.95
   2 !   29.6   0.0   1.1e-10   6.5e-07      89     149 .]    1163    1229 ..    1160    1229 .. 0.90

  Alignments for each domain:
  == domain 1  score: 39.2 bits;  conditional E-value: 1.2e-13
  Membr_traf_MHD    2 vlrPLmdyLdsnLsilaqalektvLkrvlkelWkvvlnalekllLPplsdak 53  
                      +l PL+ y++ n++i++++l+ + +k v+ +lWk vl ++e ll Pplsd+ 
      EEA18815.1 1110 ALDPLFTYFNDNFEIMNKTLTSEAMKMVMARLWKEVLVTIEGLLVPPLSDKP 1161
                      799**********************************************986 PP

  == domain 2  score: 29.6 bits;  conditional E-value: 1.1e-10
  Membr_traf_MHD   89 feksLtpkevevleaaLdtlkdfFh......agGeGlkkeaLkseelqsLllalslYdqstdeLikt 149 
                       +++Lt++ev+++ ++L  l +fF        + +G++++ Lks+++++++    +Y +std+Li+t
      EEA18815.1 1163 HQRPLTQQEVDIVSKWLGLLLTFFQvpdevtGEANGVSLDILKSPKYHEIQSLIFFYFESTDTLIRT 1229
                      69**********************7443333689*******************************86 PP

>> C2  C2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.0   0.0     2e-16   1.2e-12       3      90 ..     917    1003 ..     915    1018 .. 0.90

  Alignments for each domain:
  == domain 1  score: 48.0 bits;  conditional E-value: 2e-16
                  EEEEEEEEESSSSSSTTSSCEEEEEEEE.ECEEEEEE-SCSSSSSSEEEEEEEEEESCHTTSEEEEEEEEECSSSTEEEEEEEEEEGHH CS
          C2    3 levtvieAknLpnkdkkgssdpyvkvsl.dgkqkakTrviknslnPvWnekftfevaeleeakLeveVfdndrlskddfiGkveiplst 90  
                  ++v+++e+++L++ d++g sdpyv+++   +k++ kT+++ ++lnP+W+ ++ +  +      +  +V+d+d ++++d +G+++++l+ 
  EEA18815.1  917 FTVKIVEGEDLKACDINGWSDPYVVLTDeYQKRISKTHIVYRNLNPRWDDSVDITTKG--PLNIIATVWDWDAVGDHDYVGRTSLKLDP 1003
                  78************************9988********99*********999996665..899***********************997 PP

>> DUF810  Plant family of unknown function (DUF810)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    3.1   0.0    0.0047        28     118     154 ..     297     333 ..     285     396 .. 0.79
   2 ?   -2.1   0.0      0.17     1e+03     271     328 ..     470     522 ..     449     657 .. 0.58
   3 !   26.6   0.2   3.4e-10   2.1e-06     522     685 ..     717     885 ..     711     886 .. 0.78

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.0047
      DUF810 118 lpLeLLrqlkksdFsdekeyeaWqkRqlkiLeagLll 154
                 l+L+  + l++ dF+d ++ye W++ ++  L +++l 
  EEA18815.1 297 LTLKTGKTLSRDDFPDDESYETWKRGEAPDLSQMMLA 333
                 6667778899**************9888766665553 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.17
      DUF810 271 cfaWvLfqqyvvtgqvepdLleaalaqlkevakdakktkeeaylkllssvlasiqeWa 328
                 +f  v+ +++v  + ++ + ++aa + +k+v +++ k+++    +ll+sv+++ ++W+
  EEA18815.1 470 LFLDVIREKFVDQQ-IDLKTVDAAFTFVKQVPAQEGKKRN----SLLASVVFERNRWI 522
                 56666777777654.7777788888888888776665544....35555555555554 PP

  == domain 3  score: 26.6 bits;  conditional E-value: 3.4e-10
      DUF810 522 vesvianlvkkWvkerlkklkewveraleqEtWePks........kqeryaqSavellriieetvdeffelpv...pmkeellqdLldgldkllqeYls 609
                 ve++++++v +W+++  +k  ew+e+a +q t + +s         ++r++ Sa++++r  +++vd++ +l+        + + +L + + +++  Y++
  EEA18815.1 717 VEKLLSSFVWRWIENTDAKFMEWIEQAAKQDTFNIRSgdpndlppDDKRHSVSAIDIFRSFHQVVDDMKNLQWedtLQYAKFMTALSRSIGRAIARYCE 815
                 79999***************************99777333334334799**********************9965334467899*************** PP

      DUF810 610 kvasslg.skeslvPslPaLTRckedsklkklwkkkavepclldekrksklnslgtqkLcvrLNTLhyllsqlesle 685
                  +++    + ++l P   a    +++ k+++++k +    +++++  +     + +++  v+LN ++y  +ql++le
  EEA18815.1 816 LLEQGFTrEMDRLSPDQEASLVQSRQEKFMQMAKDAW---ANKEKIEP----FQFLPESLVKLNNIEYAVAQLDKLE 885
                 ***7776355677776655444555556667777666...22222333....34789999***************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1357 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       822  (0.0458475); expected 358.6 (0.02)
Passed bias filter:                      648  (0.0361426); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 1.02u 0.38s 00:00:01.40 Elapsed: 00:00:00.57
# Mc/sec: 7140.94
//
Query:       EEA18816.1  [L=383]
Description: mitochondrial molecular chaperone (Atp12), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.7e-43  145.9   2.4    7.2e-43  145.7   1.3    1.6  2  ATP12     ATP12 chaperone protein


Domain annotation for each model (and alignments):
>> ATP12  ATP12 chaperone protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.7   1.3     4e-47   7.2e-43       1     128 [.     105     249 ..     105     250 .. 0.96
   2 ?   -3.4   0.0      0.53   9.5e+03      43      58 ..     307     324 ..     301     332 .. 0.64

  Alignments for each domain:
  == domain 1  score: 145.7 bits;  conditional E-value: 4e-47
                 B---S-EEEEE...TTSEEEEETTEE-BETTSEB--BSSHH..HHHHHHHHHH....T-SSB--GGG-HHHHHHHHHHH.TT..C....CCHHHHHHHH CS
       ATP12   1 kRFwkevsveekekdggyqvlLDgrplrtptknilavpsskklLAeaiaaEWdl..saqqalikphllpltslasraiDleaeda....ttreaivktl 93 
                 kRFwk+v+v  ke+ +gyq+lLD+rp+r ptk+il+vps+k++LAeai  EWdl  saqqal k+hl+pltsl+ ra D+ +ed+    ++r++i++t+
  EEA18816.1 105 KRFWKDVDV--KESADGYQILLDTRPVRSPTKTILTVPSNKRHLAEAISLEWDLltSAQQAL-KQHLIPLTSLTTRAADIVREDElgqnRIRQEIARTA 200
                 8********..56889***************************************9999987.*******************9999*99********** PP

                 HHHHHC-CCCEE...............--SSHHHHHHHHHHHHHHHHHH CS
       ATP12  94 lryldtDtllcr..............eaeepesLrerqeetwepilawl 128
                 +ryl+tDtllc+               a e+e+Lre+q +++++i+++l
  EEA18816.1 201 MRYLETDTLLCWvpekeihnplsktsLAPEEETLREKQVRVAREIINFL 249
                 ************************997799****************997 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 0.53
                 .HHHHHHHHHH....T-S CS
       ATP12  43 lLAeaiaaEWdl..saqq 58 
                 l+A  +  EW+   s  q
  EEA18816.1 307 LVAVRLVVEWSEhfSGLQ 324
                 568888899997664434 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (383 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       672  (0.0374812); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.70u 0.35s 00:00:01.04 Elapsed: 00:00:00.58
# Mc/sec: 1999.84
//
Query:       EEA18817.1  [L=416]
Description: hypothetical protein PMAA_010950 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (416 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       422  (0.0235373); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.60u 0.26s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 2657.62
//
Query:       EEA18818.1  [L=914]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.1e-13   50.2   0.0    4.7e-13   49.0   0.0    1.5  1  Pkinase_Tyr  Protein tyrosine kinase
    6.9e-12   45.8   0.0    3.1e-06   27.7   0.0    3.7  4  Ank_2        Ankyrin repeats (3 copies)
    8.2e-12   45.0   0.0    9.4e-11   41.6   0.0    2.1  2  Pkinase      Protein kinase domain
    7.5e-09   35.1   1.0     0.0031   17.9   0.1    5.1  5  Ank_3        Ankyrin repeat
    1.9e-08   34.4   0.1    0.00034   20.9   0.0    3.5  3  Ank_5        Ankyrin repeats (many copies)
    3.6e-08   33.8   0.3    0.00047   20.7   0.1    4.3  6  Ank_4        Ankyrin repeats (many copies)
    0.00056   20.2   9.7      0.015   15.7   0.2    5.5  5  Ank          Ankyrin repeat
     0.0013   18.2   0.0     0.0032   16.9   0.0    1.6  1  Kdo          Lipopolysaccharide kinase (Kdo/WaaP) family
  ------ inclusion threshold ------
      0.045   13.0   0.0      0.078   12.2   0.0    1.3  1  Noc2         Noc2p family


Domain annotation for each model (and alignments):
>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.0   0.0   2.3e-16   4.7e-13      42     171 ..      27     163 ..       8     175 .. 0.78

  Alignments for each domain:
  == domain 1  score: 49.0 bits;  conditional E-value: 2.3e-16
                  HHHHHHHHHHHHHHHT..S.-BTTB--EEEEEE....SSSS....EEEEEE--TTEBHHHHHHHTCTTTSBHHHHHHHHHHHHHHHHHHHHTTEEEST CS
  Pkinase_Tyr  42 eeekeelleeakimkk..l.khpnivkllgvct....keep....llivteyvkgGdLlkfLrkkekekltlkdllsfalqvAkGmeyLeskklvHrd 128
                  ++  +++++e++im++  l k++niv+l+g+c       ++      +++e ++ GdL++f r++  +++t+++ l ++++vA+G+e L+s  ++H d
   EEA18818.1  27 RQIFDSMTKEYQIMNHggLkKNKNIVSLIGCCWrtidI-HTklvvPNLLLEGADLGDLEDFYRRS-YSTITMRRRLGLSIDVASGVEALHSVGILHDD 122
                  333678999*****99444899**********965531.22233344677888999********9.******************************** PP

                  -SGGGEEEEETTEEEE-STTTHEETTTSSEEEETTSSTSGGGG CS
  Pkinase_Tyr 129 laarNvLlsenkvvkisDfGLardiekddeyvkkeeaklpvkW 171
                  +  rN+L+ +++   +s f   ++    ++  k+e ++ ++ W
   EEA18818.1 123 IKPRNILVFQDEEQSLSTFVTRKTF--GESAAKQEIRRRNMAW 163
                  **********999999998666655..4444555555556666 PP

>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   1.7e-06    0.0033      27      80 ..     529     589 ..     513     592 .. 0.76
   2 !   27.7   0.0   1.6e-09   3.1e-06       6      78 ..     537     621 ..     532     626 .. 0.73
   3 !   14.0   0.0   2.8e-05     0.056      23      75 ..     589     662 ..     585     671 .. 0.69
   4 ?    1.7   0.0       0.2     4e+02      28      79 ..     703     728 ..     685     770 .. 0.61

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 1.7e-06
       Ank_2  27 ktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlekgadin 80 
                  t +h  a +g+le ++ L          ++  g+tp+ +A+r+gh +i+ lLl  gad+ 
  EEA18818.1 529 PTFIHNLAAHGQLERLRRLSYLpveyfdeQNGLGETPIVVACRCGHADILALLLALGADPS 589
                 688997777788888888874233354455566*********************88**986 PP

  == domain 2  score: 27.7 bits;  conditional E-value: 1.6e-09
       Ank_2   6 kngnlelvklLl....egadpn.k..ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlekgad 78 
                  +g+le ++ L     e   ++ +   g+t++ +A++ g+ +i+ lLl+        +d +  tpL +A+  g++ +v+ Ll+ gad
  EEA18818.1 537 AHGQLERLRRLSylpvE--YFDeQngLGETPIVVACRCGHADILALLLALgadpsigTDHEEGTPLLWAVITGNIVAVRNLLKLGAD 621
                 55555555555432211..122323689********************955456676667788***********99***9*977998 PP

  == domain 3  score: 14.0 bits;  conditional E-value: 2.8e-05
       Ank_2  23 n...k.ngktaLhyAakngnleivklLle.....h..........ad..ndgrtpLhyAarsghleivklLlek 75 
                 +   + ++ t+L +A++ gn+ +v+ Ll+     +          ++  +   +pL +A++  +++i+++Ll +
  EEA18818.1 589 SigtDhEEGTPLLWAVITGNIVAVRNLLKlgadtFsyrkleswqfLNsiSIWSSPLEHAIETFQYDILEVLLSS 662
                 443324566**********88889****96654415555555544335422559******99778*******54 PP

  == domain 4  score: 1.7 bits;  conditional E-value: 0.2
       Ank_2  28 taLh.yAakngnleivklLlehadndgrtpLhyAarsghleivklLlekgadi 79 
                 t Lh + +k+ +l +vk+Ll++                           ga++
  EEA18818.1 703 TLLHgCHVKQAQLRTVKTLLQY---------------------------GANP 728
                 5555555555555556666654...........................3332 PP

>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.6   0.0   4.7e-14   9.4e-11      41     137 ..      24     136 ..       5     156 .. 0.80
   2 ?    0.8   0.0      0.13   2.6e+02     233     255 ..     194     230 ..     142     240 .. 0.65

  Alignments for each domain:
  == domain 1  score: 41.6 bits;  conditional E-value: 4.7e-14
                 HH.....HHHHHHHHHHHHHS...CTTB--EEEEEEE....SSEEE...EEEE--TTEBHHHHHHHHSS.--HHHHHHHHHHHHHHHHHHHHTTEE-SS CS
     Pkinase  41 ke.....kkvlrEikilkklk...hpnivrlyevfee....kdely...lvleyveggeladllerkgs.lseeeakkiakqilegleylHskgiiHrD 123
                 ++     +++++E +i+++      +niv l++++ +    +++l+   l+le ++ g+l+d+++r+ s +++++   +   +++g+e lHs gi+H D
  EEA18818.1  24 QRnrqifDSMTKEYQIMNHGGlkkNKNIVSLIGCCWRtidiHTKLVvpnLLLEGADLGDLEDFYRRSYStITMRRRLGLSIDVASGVEALHSVGILHDD 122
                 3333456899*******98655589********999878886666567899**************776669999999********************** PP

                 -SGGGEEEETTTEE CS
     Pkinase 124 lKpeNiLidekgel 137
                 +Kp NiL+ +++e 
  EEA18818.1 123 IKPRNILVFQDEEQ 136
                 *******9977764 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.13
                 S.............-HHHHHHHHHHT-SSGCCSTT.H CS
     Pkinase 233 i.............seeakdllkkllkkdpkkRlt.a 255
                               ++ + d+++++ + +p+kR++  
  EEA18818.1 194 WitlkndtlksqagEQLFHDFVDQMTSGEPTKRPSnT 230
                 0444444445555588899***************953 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.0         9   1.8e+04       5      21 ..     531     547 ..     530     547 .. 0.78
   2 !   17.9   0.1   1.5e-06    0.0031       2      30 ..     562     589 ..     561     590 .. 0.93
   3 !    8.0   0.0    0.0025       4.9       4      28 ..     598     621 ..     595     622 .. 0.94
   4 ?   -0.2   0.0       1.2   2.4e+03       4      23 ..     642     661 ..     641     665 .. 0.90
   5 ?    2.8   0.0      0.13   2.6e+02       4      29 ..     703     728 ..     703     730 .. 0.89

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 9
       Ank_3   5 pLhlAarsgnleivkfL 21 
                  +h  a +g le+++ L
  EEA18818.1 531 FIHNLAAHGQLERLRRL 547
                 57999999999988765 PP

  == domain 2  score: 17.9 bits;  conditional E-value: 1.5e-06
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 Getp+ +A+r+g+ +i+ +Ll   gad+ 
  EEA18818.1 562 GETPIVVACRCGHADILALLLA-LGADPS 589
                 9**************9999999.****97 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.0025
       Ank_3   4 tpLhlAarsgnleivkfLlenkgad 28 
                 tpL +A+  gn+  v+ Ll+  gad
  EEA18818.1 598 TPLLWAVITGNIVAVRNLLK-LGAD 621
                 9***********99******.9998 PP

  == domain 4  score: -0.2 bits;  conditional E-value: 1.2
       Ank_3   4 tpLhlAarsgnleivkfLle 23 
                 +pL +A++   ++i++ Ll 
  EEA18818.1 642 SPLEHAIETFQYDILEVLLS 661
                 7999*************997 PP

  == domain 5  score: 2.8 bits;  conditional E-value: 0.13
       Ank_3   4 tpLh.lAarsgnleivkfLlenkgadv 29 
                 t+Lh + ++++ l  vk Ll+ +ga++
  EEA18818.1 703 TLLHgCHVKQAQLRTVKTLLQ-YGANP 728
                 789999999999988******.***97 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.0   1.7e-07   0.00034      12      46 ..     558     592 ..     553     597 .. 0.89
   2 !    9.5   0.0   0.00061       1.2      14      43 ..     595     623 ..     589     627 .. 0.87
   3 ?   -1.0   0.0       1.2   2.5e+03      16      36 ..     640     660 ..     636     670 .. 0.84

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 1.7e-07
       Ank_5  12 ldgggntpLhvAakygaadvvrlLlargadlnltd 46 
                 ++g g+tp+ vA+++g+ad++ lLla gad+ + +
  EEA18818.1 558 QNGLGETPIVVACRCGHADILALLLALGADPSIGT 592
                 577899************************98766 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00061
       Ank_5  14 gggntpLhvAakygaadvvrlLlargadln 43 
                 ++g tpL +A+  g+   vr+Ll+ gad++
  EEA18818.1 595 EEG-TPLLWAVITGNIVAVRNLLKLGADTF 623
                 556.***********************986 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 1.2
       Ank_5  16 gntpLhvAakygaadvvrlLl 36 
                 + +pL +A++    d++++Ll
  EEA18818.1 640 WSSPLEHAIETFQYDILEVLL 660
                 5699******99999999999 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.7   0.1   2.3e-07   0.00047       3      55 .]     530     582 ..     529     582 .. 0.96
   2 !    8.7   0.0    0.0014       2.7      13      51 ..     574     612 ..     573     616 .. 0.88
   3 ?    1.5   0.0      0.25     5e+02       3      27 ..     598     634 ..     596     660 .. 0.60
   4 ?   -1.6   0.0       2.3   4.6e+03       3      23 ..     642     662 ..     640     675 .. 0.79
   5 ?    4.6   0.0     0.025        50       5      28 ..     705     729 ..     701     736 .. 0.75
   6 ?   -3.9   0.0         9   1.8e+04      20      30 ..     861     871 ..     860     874 .. 0.82

  Alignments for each domain:
  == domain 1  score: 20.7 bits;  conditional E-value: 2.3e-07
       Ank_4   3 taLhyaaisgrlelvrlLlekgad.inaqdnrsGetalhiAakrgnveilklLl 55 
                 t +h++a++g+le +r+L +  ++  ++q n+ Get++  A++ g+ +il lLl
  EEA18818.1 530 TFIHNLAAHGQLERLRRLSYLPVEyFDEQ-NGLGETPIVVACRCGHADILALLL 582
                 569****************999999****.********************9997 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.0014
       Ank_4  13 rlelvrlLlekgadinaqdnrsGetalhiAakrgnveil 51 
                 + ++++lLl+ gad+   ++ +  t+l  A+ +gn+ ++
  EEA18818.1 574 HADILALLLALGADPSIGTDHEEGTPLLWAVITGNIVAV 612
                 66899*********99999****************8555 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.25
       Ank_4   3 taLhyaaisgrlelvrlLlekgad............i 27 
                 t+L +a+i g++ +vr Ll  gad            +
  EEA18818.1 598 TPLLWAVITGNIVAVRNLLKLGADtfsyrkleswqfL 634
                 7888899989888888888888886555555554444 PP

  == domain 4  score: -1.6 bits;  conditional E-value: 2.3
       Ank_4   3 taLhyaaisgrlelvrlLlek 23 
                 ++L +a++ +++++++ Ll++
  EEA18818.1 642 SPLEHAIETFQYDILEVLLSS 662
                 789999999999999999964 PP

  == domain 5  score: 4.6 bits;  conditional E-value: 0.025
       Ank_4   5 Lhyaai..sgrlelvrlLlekgadin 28 
                 Lh  ++  + +l++v+ Ll++ga++ 
  EEA18818.1 705 LH-GCHvkQAQLRTVKTLLQYGANPL 729
                 43.3334799*************986 PP

  == domain 6  score: -3.9 bits;  conditional E-value: 9
       Ank_4  20 Llekgadinaq 30 
                  l++g+d+++q
  EEA18818.1 861 FLNSGVDLYEQ 871
                 5899****998 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.3      0.82   1.6e+03      15      30 ..      49      65 ..      40      85 .. 0.54
   2 ?   -1.6   0.0       2.2   4.5e+03       6      15 ..     429     441 ..     429     470 .. 0.73
   3 !   15.7   0.2   7.6e-06     0.015       2      30 ..     562     591 ..     561     593 .. 0.90
   4 ?    1.2   0.0      0.29   5.7e+02       4      26 ..     598     621 ..     598     624 .. 0.70
   5 ?    3.8   0.1     0.043        86       5      29 ..     704     730 ..     687     733 .. 0.69

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.82
                HHHHHHHHTTTS...TTCB CS
         Ank 15 kriiklLLhGAn...lnal 30
                k+i++ L+ G++   ++++
  EEA18818.1 49 KNIVS-LI-GCCwrtIDIH 65
                55666.44.4332223333 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 2.2
                 HHHHHHHTT...H CS
         Ank   6 LHlAatngk...k 15 
                 LHl at g+    
  EEA18818.1 429 LHLSATLGHheaQ 441
                 9*99999985542 PP

  == domain 3  score: 15.7 bits;  conditional E-value: 7.6e-06
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTCB CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlnal 30 
                 G TP  +A+++g+++i+ lLL  GA++ + 
  EEA18818.1 562 GETPIVVACRCGHADILALLLaLGADPSIG 591
                 89******************966***9875 PP

  == domain 4  score: 1.2 bits;  conditional E-value: 0.29
                 BHHHHHH.HHTTHHHH..HHHH.TTTS CS
         Ank   4 TPLHlAa.tngkkrii..klLL.hGAn 26 
                 TPL +A+ t++   i+  ++LL  GA+
  EEA18818.1 598 TPLLWAViTGN---IVavRNLLkLGAD 621
                 9****996654...5522669944998 PP

  == domain 5  score: 3.8 bits;  conditional E-value: 0.043
                 HHHHHHHHTT..HHHHHHHH.TTTSTTC CS
         Ank   5 PLHlAatngk..kriiklLL.hGAnlna 29 
                  LH  ++ ++  +r +k LL +GAn+ +
  EEA18818.1 704 LLHG-CHVKQaqLRTVKTLLqYGANPLQ 730
                 4443.3222245899*****77***965 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.0   1.6e-06    0.0032     102     158 ..      80     137 ..      72     144 .. 0.83

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 1.6e-06
         Kdo 102 aqdLedllakwae.laeelkrallkavgrliaklhragvnHadlyaknillqqeeeee 158
                   dLed++++  + +  +++  l  +v+  ++ lh++g+ H d+ ++nil+ q+ee+ 
  EEA18818.1  80 LGDLEDFYRRSYStITMRRRLGLSIDVASGVEALHSVGILHDDIKPRNILVFQDEEQS 137
                 46999999985555777777778899*************************9998554 PP

>> Noc2  Noc2p family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   3.9e-05     0.078      62      99 ..     612     650 ..     592     675 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 3.9e-05
        Noc2  62 LRnalktkk.keayksvynWqfvhsldlWsrvlsaacsk 99 
                 +Rn lk      +y++  +Wqf++s+ +Ws+ l +a+++
  EEA18818.1 612 VRNLLKLGAdTFSYRKLESWQFLNSISIWSSPLEHAIET 650
                 66666665425689*****************99998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (914 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       492  (0.0274416); expected 358.6 (0.02)
Passed bias filter:                      402  (0.0224218); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.75u 0.29s 00:00:01.04 Elapsed: 00:00:00.48
# Mc/sec: 5758.31
//
Query:       EEA18819.1  [L=453]
Description: polysaccharide synthase Cps1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.4e-32  111.5   0.1    7.1e-32  111.1   0.1    1.1  1  Glyco_tranf_2_3  Glycosyltransferase like family 2
    1.1e-08   35.0   0.0      2e-08   34.3   0.0    1.4  1  Glycos_transf_2  Glycosyl transferase family 2
    1.6e-06   27.8   0.0    2.5e-05   23.8   0.0    2.1  1  Glyco_transf_21  Glycosyl transferase family 21
      0.004   17.1   4.2      0.009   15.9   4.2    1.7  1  Glyco_trans_2_3  Glycosyl transferase family group 2
  ------ inclusion threshold ------
        0.1   11.7   0.1       0.22   10.6   0.1    1.5  1  Phage_GPA        Bacteriophage replication gene A protein (GP


Domain annotation for each model (and alignments):
>> Glyco_tranf_2_3  Glycosyltransferase like family 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.1   0.1     2e-35   7.1e-32       3     229 ..      45     286 ..      43     287 .. 0.88

  Alignments for each domain:
  == domain 1  score: 111.1 bits;  conditional E-value: 2e-35
  Glyco_tranf_2_3   3 dlavlVptfne.edvlgevlesllaqeyprvevvvvv.desdaetlevaeelaaalpdvrvrvvvnarnlgstgksralnealravksdlvllv 94 
                      d++v+Vp+++   d+l+e+++ +l     + e+ +v+ + +++++ ++++++ a l d r+r+ + ++ +    k+r + +a++ v++ ++++ 
       EEA18819.1  45 DVTVIVPSLEGcGDELVETIRTILD--TKPHELLLVTiEANRKDAEKMLKAMPAYLHD-RIRLFTITH-P---NKRRQMTRAIPEVRTSITIFA 131
                      699*****976256**********9..5667777777677888888**********99.999887778.3...58999**************** PP

  Glyco_tranf_2_3  95 DdDtvvePdtlkrllqff.ltpkvgavgtpvfllnrstl......vsalgalefaerhlrflaarralg.vltlnGsgslirrevlkele.... 176
                      DdD+ + P++l+++l+ f  ++++g v t+++l++  +       +++lgal++++r++++ a+++  g v++l+G+++++r+++l++      
       EEA18819.1 132 DDDVSWPPTALPWILAPFdTDERYGGVVTCQRLRRAVNPtfsekiWNFLGALYLERRNFDCAATTHIDGgVPCLSGRTVAYRTKILQDEVftnd 225
                      ******************9999***********864433335666*********************99879*********************** PP

  Glyco_tranf_2_3 177 ......gldp.lflltdDyelglrlrragfrtayvpgaavrevfp.sslkayikqrnRwvy 229
                             +++ + +  dD+++++++ ++g+ t+++++++v+  ++ ++  ++ kq++Rw++
       EEA18819.1 226 ftneewWFGKyQLNADDDNFITRWMVSHGWETYIQYHPEVEVKTTlENNPKFLKQCARWSR 286
                      ****866777999********************888888888877567999********86 PP

>> Glycos_transf_2  Glycosyl transferase family 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.3   0.0   5.5e-12     2e-08       1     167 [.      47     218 ..      47     220 .. 0.86

  Alignments for each domain:
  == domain 1  score: 34.3 bits;  conditional E-value: 5.5e-12
                      EEEEEESS-.TTTHHHHHHHHHHHGGCCEEEEEEEEES-SSCHHHHHGGGCH.C-TTEEEEEESSS-HHHHHHHHHHHH--SSEEEEEESSEEE CS
  Glycos_transf_2   1 svviptyNe.ektlletlesllaqdpypdfeiivvDDgStDetveileelak.edprvrvirreenvGkagalnaglraatgdyilflDaDdep 92 
                      +v++p+     ++l et++ +l+ +p++ + + +   + + +++++l++  +   +r+r+++ ++   k + + +++ ++++ + +f D+D+ +
       EEA18819.1  47 TVIVPSLEGcGDELVETIRTILDTKPHELLLVTI--EANRKDAEKMLKAMPAyLHDRIRLFTITHP-NKRRQMTRAIPEVRTSITIFADDDVSW 137
                      699****999*************93333333333..333558888888887799999999999999.*************************** PP

                      -TTHHHHHHHHHHH.TT..CEEEEEEEEEECCCCCCCHC-SS....EEEECCHCCCCHCCCCCCSTTCSTCCCEEEEHHHH CS
  Glycos_transf_2  93 dpdwleklvealekdga..dvvlgqrprifgetdeiernkrv....generlyfkerkrslkgnlsfeigsaallrreale 167
                      +p  l+ ++++++ d++  +vv +qr r+ +++++ e+ +++    + + r +       ++g++++ +g   ++r ++l+
       EEA18819.1 138 PPTALPWILAPFDTDERygGVVTCQRLRRAVNPTFSEKIWNFlgalYLERRNFDCAATTHIDGGVPCLSGRTVAYRTKILQ 218
                      **************96633689******************99999888888888888888888999999999999999986 PP

>> Glyco_transf_21  Glycosyl transferase family 21
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.0   6.9e-09   2.5e-05      18     173 .]     112     286 ..     105     286 .. 0.72

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 6.9e-09
  Glyco_transf_21  18 KvnnllqaleaakydllvisDsdvrvkpdyLeellaaled.pk.vglVts..lpvgsdak...glaaaleaafl...ntlagvlqa.kl.sglg 99 
                      K  ++ +a++++++++++++D+dv  +p++L  +la++ + ++  g+Vt+  l +++++    ++++ l a++l   n     ++  +  +g+ 
       EEA18819.1 112 KRRQMTRAIPEVRTSITIFADDDVSWPPTALPWILAPFDTdERyGGVVTCqrLRRAVNPTfseKIWNFLGALYLerrN--FDCAATtHIdGGVP 203
                      66689999******************************8744414566663344455544444588888888886433..33333323547*** PP

  Glyco_transf_21 100 favGksmalrreaLeaiGGfealade........L.A.eDyalgkllraaGlkvvlspapiaqtsvpr.rsslrallaRqlrWar 173
                      +  G ++a+r+++L++    + +  e        L A +D ++++++ ++G+ +++  +p ++  v++  +   ++l++  rW+r
       EEA18819.1 204 CLSGRTVAYRTKILQDEVFTNDFTNEewwfgkyqLnAdDDNFITRWMVSHGWETYIQYHPEVE--VKTtLENNPKFLKQCARWSR 286
                      ***************99888877543222222224333789******************9554..54433455679*******97 PP

>> Glyco_trans_2_3  Glycosyl transferase family group 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   4.2   2.5e-06     0.009       3     192 ..     129     331 ..     127     405 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 2.5e-06
  Glyco_trans_2_3   3 lllDaDtvlppdclreiaaela.spevaivqgpvlvm.nvanwleelaalf....faedhgkdilvrealgrvvpsv.Gsgaflrrsalqevg. 88 
                      ++ D+D   pp  l  i+a ++ + +++ v ++   + +v++ ++e +  f    + e+ ++d+  +  + + vp+  G+ ++ r + lq+ + 
       EEA18819.1 129 IFADDDVSWPPTALPWILAPFDtDERYGGVVTCQRLRrAVNPTFSEKIWNFlgalYLERRNFDCAATTHIDGGVPCLsGRTVAYRTKILQDEVf 222
                      5679999999999999999999568898777776664478888888888776777899999**************999************6662 PP

  Glyco_trans_2_3  89 ........gwdgdessvsEDfdmglrlq.rkGyrv..rfvpeslvkekspltlraalrQrkRwayGceleklillvrllgylgsllwsalplhl 171
                              +w g+ +  ++D ++  r + ++G+ +   ++pe+ vk+  ++    +l+Q +Rw + +     ++   ++ ++ +++w   p++ 
       EEA18819.1 223 tndftneeWWFGKYQLNADDDNFITRWMvSHGWETyiQYHPEVEVKTTLEN-NPKFLKQCARWSRSN-----WRSNLTSMFAERYIWYRQPWST 310
                      444444444444444555555555665536665552234455544444444.677***********5.....7666677899999********* PP

  Glyco_trans_2_3 172 allllfsllalalvlllllll 192
                      ++++l+ l++ al+  +ll++
       EEA18819.1 311 YAVHLTTLSPPALLGDCLLIY 331
                      999999999988888666554 PP

>> Phage_GPA  Bacteriophage replication gene A protein (GPA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.1   6.1e-05      0.22      75     149 ..     226     297 ..     197     300 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 6.1e-05
   Phage_GPA  75 ltcekwwlrklkkvrkrwreelaiavgeVskkaspyaskealkeireqkrknleflkslelededgetidLeevv 149
                  t+e+ww+ k +    +  ++  i+   Vs+ ++ y+ +++  e++   ++n +flk++   ++ + + +L +++
  EEA18819.1 226 FTNEEWWFGKYQ---LNADDDNFITRWMVSHGWETYIQYHPEVEVKTTLENNPKFLKQCARWSRSNWRSNLTSMF 297
                 689******998...4455555667777*******************************9999999888888877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (453 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       464  (0.0258799); expected 358.6 (0.02)
Passed bias filter:                      381  (0.0212505); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.56u 0.25s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 3159.11
//
Query:       EEA18820.1  [L=1251]
Description: oxysterol binding protein (Osh1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   7.7e-134  446.2   0.1   2.2e-133  444.7   0.0    1.8  2  Oxysterol_BP  Oxysterol-binding protein
    1.9e-14   53.5   0.2    1.5e-09   37.9   0.1    3.6  3  Ank_5         Ankyrin repeats (many copies)
    5.9e-12   46.0   0.0    1.1e-07   32.4   0.0    3.4  3  Ank_2         Ankyrin repeats (3 copies)
    1.4e-11   44.3   0.1     0.0057   17.0   0.0    4.1  4  Ank           Ankyrin repeat
    1.9e-11   44.2   0.1    1.5e-05   25.5   0.1    3.7  3  Ank_4         Ankyrin repeats (many copies)
    1.2e-10   41.8   0.4    2.7e-10   40.7   0.4    1.6  1  PH            PH domain
    1.3e-09   37.4   0.0      0.017   15.6   0.0    3.9  3  Ank_3         Ankyrin repeat
    7.7e-07   29.3   0.6    2.1e-06   27.9   0.6    1.8  1  PH_8          Pleckstrin homology domain
    0.00031   21.1   2.0    0.00031   21.1   2.0    2.7  2  PH_11         Pleckstrin homology domain
  ------ inclusion threshold ------
        0.7   10.5   5.7       0.14   12.7   1.4    2.0  2  LLC1          Normal lung function maintenance, Low in Lung C


Domain annotation for each model (and alignments):
>> Oxysterol_BP  Oxysterol-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.2      0.78   1.4e+03     214     258 ..     443     493 ..     426     519 .. 0.59
   2 !  444.7   0.0  1.2e-136  2.2e-133       1     373 []     878    1237 ..     878    1237 .. 0.95

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 0.78
                   EEETTS-EEEEEEEETTTEEEEEETTSTTS--EEEEETT......-.BSXXG CS
  Oxysterol_BP 214 vkdkkkevlyeisGkwdeelyikkkktekkeeeedasek......s.kvkek 258
                    +d+++++++ei Gk + ++++k ++   + ++ ++  +      + ++ke+
    EEA18820.1 443 HMDAQDKTRFEILGKSSVKYHLKANHVV-EAKRWFWALNnaiqwaKdEAKEE 493
                   4678889999999999999999666554.44444454443333221211222 PP

  == domain 2  score: 444.7 bits;  conditional E-value: 1.2e-136
                    HHHCCHTTSTT-BCCCS---GGGEEEEEHHHHHHHCCTTCHHHHHHHC.SSHHHHHHHHHHHHHHCCCGCTSTSSSEEE---TT-EEEEEETTCE CS
  Oxysterol_BP    1 slwsilkkciGkDLskislPvffneplSlLqrlaedleyselLdkaakeddsleRlayVaaFalSsyastikrrlkKPFNPlLGEtfelvredkg 95  
                    slw ilk++iGkD++k++lPv+fnep+SlLqr+aed+ey++lLd aa+ +dsleRl+yVaa+a+S+yasti +r++KPFNPlLGEtfe++r+dk+
    EEA18820.1  878 SLWGILKSMIGKDMTKMTLPVSFNEPTSLLQRVAEDMEYADLLDIAADRTDSLERLLYVAAYAISEYASTI-GRVAKPFNPLLGETFEYTRPDKQ 971 
                    79**********************************************999********************.9********************** PP

                    EEEEEEEEETTTTEEEEEEEECTEEEEEEEEEEEEE-SSEEEEEE-SEEEEEE..EEESEEEEEEE--EEEEE-TTTTS-EEEEEEEEEEEETTT CS
  Oxysterol_BP   96 frfiaEQVsHhPpvsAfhaesegweldgeikvkskflgkslevkpeGtahlel..lkksgehYtwtkpttivhniivgklwvelsgeveitnhst 188 
                    +rf  EQVsHhPp+ A +aes++w ++ge+++kskf+gks+++++ Gt++++l     ++e Ytw+k+t++v +ii+g+++v+++g +e++n +t
    EEA18820.1  972 YRFYVEQVSHHPPIGAAWAESPRWDYYGESALKSKFYGKSFDINLLGTWFCKLrpITGEEEVYTWKKVTSSVIGIITGNPTVDNYGPMEVKNWKT 1066
                    *****************************************************64356999********************************** PP

                    --EEEEEEE---SSS---SSEEEEEEEETTS-EEEEEEEETTTEEEEEETTSTTS--EEEEETT-BSXXGCGSSTTBCCCCCCH-----...GGG CS
  Oxysterol_BP  189 gdkakleFkkkglfsskksnkvegkvkdkkkevlyeisGkwdeelyikkkktekkeeeedasekskvkekeeqeefeseklWkasplpkaeeyyg 283 
                    g+++ l+Fk++g+  ++++++v+gkv+d+++ ++y+i G+w+++++++ ++ ++               +e  e++++ +lW+a+ +p +  +++
    EEA18820.1 1067 GETCYLDFKARGWK-ASSAYQVTGKVVDASGVTRYSIGGRWNDKIFARAVSGQNG--------------TEPDESSKAILLWQANVRP-SGIPFN 1145
                    ************77.689*****************************87776433..............34556788999****8877.355*** PP

                    --HHHHCCT---.TT.GGS-TTBGGG-HHHHHHHTT-HHHHHHHHHHHHHHHHHHHHHHCCTT.----SSEEEEETTTTSSCEEEC-S-HHH CS
  Oxysterol_BP  284 ftkfavtlNeieeke.kslaptDsRlRpDqraleegdideAeeeKkrlEekQRerrkereekk.ewkpkwFekekdpdtgeevwkykgeywe 373 
                    +t+f +tlN i ++  ++l+ptD+RlRpDqra+e+g++d A++eK+r+EekQR++r+ere+++ e+ p+wF+k k p+tgee+w+ +geyw+
    EEA18820.1 1146 LTPFVLTLNAIPDRLrPFLPPTDTRLRPDQRAMEDGEYDLAATEKHRVEEKQRAKRREREQNGeEFVPQWFQKAKCPVTGEEYWESTGEYWK 1237
                    ************9778*******************************************776647**************************6 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.4   0.0   0.00037      0.66      16      43 ..     154     181 ..     152     182 .. 0.92
   2 !   37.9   0.1   8.4e-13   1.5e-09       5      56 .]     177     230 ..     173     230 .. 0.96
   3 ?    4.3   0.0      0.03        53      18      52 ..     298     332 ..     289     335 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00037
       Ank_5  16 gntpLhvAakygaadvvrlLlargadln 43 
                 g+t+Lh+A+ +  ++vv++ +a gad++
  EEA18820.1 154 GTTILHLAIQCADLQVVEYVVASGADID 181
                 89*******************9999986 PP

  == domain 2  score: 37.9 bits;  conditional E-value: 8.4e-13
       Ank_5   5 g.padvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltaldlA 56 
                 g ++dvn++d++gntpLh+Aa  g+ +vv+ Ll  ++ d  + + rG+taldlA
  EEA18820.1 177 GaDIDVNARDREGNTPLHLAAQLGRDSVVQSLLdLPQIDDSVANYRGQTALDLA 230
                 6679*************************************************9 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.03
       Ank_5  18 tpLhvAakygaadvvrlLlargadlnltdsrGlta 52 
                 t Lh  a++    ++++Ll +gad++ +d+ G+++
  EEA18820.1 298 TLLHEGARKKDTKLLQILLLHGADPFRRDKKGKLP 332
                 7777778888889999****************988 PP

>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   9.5e-06     0.017      36      82 ..     129     183 ..     119     186 .. 0.70
   2 !   32.4   0.0   5.9e-11   1.1e-07       1      60 [.     158     230 ..     158     241 .. 0.84
   3 !    6.7   0.0     0.006        11      44      83 .]     286     326 ..     267     326 .. 0.77

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 9.5e-06
       Ank_2  36 ngnleiv.klLleh.....ad..ndgrtpLhyAarsghleivklLlekgadinlk 82 
                 +g++  + ++L e+     a     g+t+Lh+A+++  l++v++ + +gadi+++
  EEA18820.1 129 SGDTTSIsRALREAkeqsaAGgpAAGTTILHLAIQCADLQVVEYVVASGADIDVN 183
                 5555434144444334443225666*********99999*******999988765 PP

  == domain 2  score: 32.4 bits;  conditional E-value: 5.9e-11
       Ank_2   1 LhlAakngnlelvklLl.egadpn..k...ngktaLhyAakngnleivklLle..h.....adndgrtpLhyA 60 
                 LhlA++  +l++v++ + +gad++      +g+t+Lh+Aa+ g   +v+ Ll+  +     a++ g+t+L +A
  EEA18820.1 158 LHLAIQCADLQVVEYVVaSGADIDvnArdrEGNTPLHLAAQLGRDSVVQSLLDlpQiddsvANYRGQTALDLA 230
                 899*9987799******9999998852569*************9899*****9552567788899*****999 PP

  == domain 3  score: 6.7 bits;  conditional E-value: 0.006
       Ank_2  44 lLlehad.ndgrtpLhyAarsghleivklLlekgadinlkd 83 
                 l  + ++ ++g t Lh  ar++ ++++++Ll +gad+ ++d
  EEA18820.1 286 LVTDTVTaQSGGTLLHEGARKKDTKLLQILLLHGADPFRRD 326
                 333333348899*********999*******99***97765 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   1.6e-05      0.03       2      31 ..     154     186 ..     153     187 .. 0.89
   2 !   17.0   0.0   3.2e-06    0.0057       2      22 ..     189     209 ..     188     217 .. 0.85
   3 ?   -2.4   0.0       4.4   7.8e+03       2      11 ..     223     232 ..     222     244 .. 0.80
   4 !    7.4   0.0    0.0036       6.4       4      31 ..     298     326 ..     295     327 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 1.6e-05
                 SBBHHHHHHHHTTHHHHHHHH.TTTS..TTCBT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAn..lnald 31 
                 G T LHlA+++++++++++ + +GA+  +na+d
  EEA18820.1 154 GTTILHLAIQCADLQVVEYVVaSGADidVNARD 186
                 889******************99*975599998 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 3.2e-06
                 SBBHHHHHHHHTTHHHHHHHH CS
         Ank   2 GnTPLHlAatngkkriiklLL 22 
                 GnTPLHlAa+ g  ++++ LL
  EEA18820.1 189 GNTPLHLAAQLGRDSVVQSLL 209
                 9********999999***998 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 4.4
                 SBBHHHHHHH CS
         Ank   2 GnTPLHlAat 11 
                 G T+L lA t
  EEA18820.1 223 GQTALDLART 232
                 99***99754 PP

  == domain 4  score: 7.4 bits;  conditional E-value: 0.0036
                 BHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnlnald 31 
                 T LH  a+ +++  ++ LL hGA++  +d
  EEA18820.1 298 TLLHEGARKKDTKLLQILLlHGADPFRRD 326
                 8899999888899***8888****98887 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.5   0.1   8.3e-09   1.5e-05       2      44 ..     155     198 ..     154     201 .. 0.90
   2 !    9.4   0.0   0.00092       1.7       6      42 ..     194     230 ..     194     230 .. 0.85
   3 !    9.9   0.0   0.00063       1.1       3      35 ..     298     329 ..     296     332 .. 0.91

  Alignments for each domain:
  == domain 1  score: 25.5 bits;  conditional E-value: 8.3e-09
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgad..inaqdnrsGetalhiAak 44 
                 +t+Lh a++  +l++v++ +++gad  +na+ +r+G+t+lh Aa+
  EEA18820.1 155 TTILHLAIQCADLQVVEYVVASGADidVNAR-DREGNTPLHLAAQ 198
                 799*****************9985555****.***********96 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.00092
       Ank_4   6 hyaaisgrlelvrlLlek.gadinaqdnrsGetalhiA 42 
                 h aa+ gr  +v++Ll+   +d + ++n +G+tal+ A
  EEA18820.1 194 HLAAQLGRDSVVQSLLDLpQID-DSVANYRGQTALDLA 230
                 88999***********765566.5559********987 PP

  == domain 3  score: 9.9 bits;  conditional E-value: 0.00063
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsG 35 
                 t+Lh  a + +++l+++Ll +gad+ ++ ++ G
  EEA18820.1 298 TLLHEGARKKDTKLLQILLLHGADPFRR-DKKG 329
                 89**************************.8877 PP

>> PH  PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.7   0.4   1.5e-13   2.7e-10       2     104 ..     391     483 ..     390     484 .. 0.93

  Alignments for each domain:
  == domain 1  score: 40.7 bits;  conditional E-value: 1.5e-13
                 EEEEEEEEETSSSSCSEEEEEEEEETTEEEEESSTTCTTESSEEEEEESTTEEEEEEECTTSSSSTSEEEEEESTSSSTEEEEEEESSHHHHHHHHHHH CS
          PH   2 vkeGwLlkkgsgkkkswkkrwfvLkdsellyykndksekdkepkgsislsncevvevvatedpkrkfcfelriverngsrtyllqasseeerkeWikai 100
                 +++G+L+k+++  + ++k rwfvL d++l+yyk + ++  +  +g is++ ++        d++ k  fe+  +  ++  +y+l+a+   e+k+W  a+
  EEA18820.1 391 EMKGYLKKWTNYTS-GFKLRWFVLEDGVLSYYKHQ-DDAGSACRGAISMRIAKLHM-----DAQDKTRFEILGK--SS-VKYHLKANHVVEAKRWFWAL 479
                 79***********9.********************.9999999*****99999964.....9*********666..55.9******************* PP

                 HHHH CS
          PH 101 qsai 104
                 ++ai
  EEA18820.1 480 NNAI 483
                 *998 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   0.0    0.0012       2.2       4      30 ..     156     181 ..     153     182 .. 0.93
   2 !   15.6   0.0   9.3e-06     0.017       1      27 [.     188     214 ..     188     215 .. 0.89
   3 !    8.0   0.0    0.0029       5.2       2      29 ..     296     322 ..     295     322 .. 0.94

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0012
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadvn 30 
                 t+LhlA+ +++l +v++ +   gad++
  EEA18820.1 156 TILHLAIQCADLQVVEYVVA-SGADID 181
                 99******************.8***98 PP

  == domain 2  score: 15.6 bits;  conditional E-value: 9.3e-06
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkga 27 
                 +G+tpLhlAa  g+ ++v+ Ll+ + +
  EEA18820.1 188 EGNTPLHLAAQLGRDSVVQSLLDLPQI 214
                 69********************96655 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.0029
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadv 29 
                 G t+Lh+ ar  ++++++ Ll  +gad+
  EEA18820.1 296 GGTLLHEGARKKDTKLLQILLL-HGADP 322
                 679*******************.9**97 PP

>> PH_8  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.9   0.6   1.2e-09   2.1e-06       4      88 ..     396     482 ..     394     483 .. 0.82

  Alignments for each domain:
  == domain 1  score: 27.9 bits;  conditional E-value: 1.2e-09
        PH_8   4 lkkrrkklqgyakRfFvLdlksstlsYyrddnss..alrgkiplslaiisanee.kreiiidsGaev.WeLkasnekdfqeWvealeka 88 
                 lkk    + g++ R+FvL  + + lsYy++++++  a rg+i++++a + ++++ k+++ i     v ++Lka+   ++++W  al++a
  EEA18820.1 396 LKKWTNYTSGFKLRWFVL--EDGVLSYYKHQDDAgsACRGAISMRIAKLHMDAQdKTRFEILGKSSVkYHLKANHVVEAKRWFWALNNA 482
                 577888899*********..9*******988776669**********7766654155666666555559****************9975 PP

>> PH_11  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.1   2.0   1.8e-07   0.00031       1      68 [.     392     459 ..     392     514 .. 0.67
   2 ?   -0.3   0.1       0.8   1.4e+03      37      75 ..     672     715 ..     654     735 .. 0.57

  Alignments for each domain:
  == domain 1  score: 21.1 bits;  conditional E-value: 1.8e-07
       PH_11   1 vkGylkk..kgskaWkrrwfavlkdgvLeyYksekkkvvkhviklSngseaklkadlisaalfkidsirs 68 
                 +kGylkk  ++  + k rwf vl+dgvL+yYk + +   +  + +     akl++d++++ +f+i  + s
  EEA18820.1 392 MKGYLKKwtNYTSGFKLRWF-VLEDGVLSYYKHQDDAG-SACRGAISMRIAKLHMDAQDKTRFEILGKSS 459
                 6898765116666*******.***********777777.5566666666667777777766665444433 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.8
       PH_11  37 vkhviklSngseaklkadlisaalfkidsirs.....sksddll 75 
                 +  ++k+S+  +a ++  l + + + + + +s     +++++l+
  EEA18820.1 672 LANLMKISRDRDAYWQYRLDKESDTRKMWEESmarivQEHEELQ 715
                 44456677777777777777777666666666555443333333 PP

>> LLC1  Normal lung function maintenance, Low in Lung Cancer 1 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.2       6.4   1.1e+04      34      64 ..     483     510 ..     459     527 .. 0.47
   2 ?   12.7   1.4   7.9e-05      0.14       4      55 ..     682     734 ..     681     747 .. 0.80

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 6.4
        LLC1  34 eellekekevekkekpkielpeklrirpvtp 64 
                  + +++e++ e+k++++     ++    + +
  EEA18820.1 483 IQWAKDEAKEEEKRRNR---DAEFLQAKIHN 510
                 34444444322222222...22222233333 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 7.9e-05
        LLC1   4 qdeiwkdhvkaEleaakrWpekwgfltteleellekekevekkekpk.ielpe 55 
                 +d  w++++ +E++++k W+e+   + +e eel+ k  e+e+k+k +  +l+e
  EEA18820.1 682 RDAYWQYRLDKESDTRKMWEESMARIVQEHEELQLKVGESEEKRKRTkKALKE 734
                 5889****************************999988877555544044444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1251 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1116  (0.0622455); expected 358.6 (0.02)
Passed bias filter:                      497  (0.0277205); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.92u 0.31s 00:00:01.23 Elapsed: 00:00:00.48
# Mc/sec: 7769.60
//
Query:       EEA18821.1  [L=529]
Description: mRNA processing protein (Mss51), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      8e-29   99.5   5.1      8e-29   99.5   5.1    1.8  2  zf-Mss51  Zinc-finger of mitochondrial splicing suppressor 51
     0.0008   19.5   3.6     0.0015   18.5   0.4    2.3  2  zf-MYND   MYND finger
  ------ inclusion threshold ------
      0.015   15.2   2.0        1.3    9.0   0.2    2.4  2  zf-HIT    HIT zinc finger
        1.1    8.9   3.8        4.6    6.9   0.1    2.5  2  zf_UBZ    Ubiquitin-Binding Zinc Finger


Domain annotation for each model (and alignments):
>> zf-Mss51  Zinc-finger of mitochondrial splicing suppressor 51
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.3       3.6   1.6e+04      16      22 ..       4      10 ..       3      11 .. 0.86
   2 !   99.5   5.1   1.8e-32     8e-29       1      57 []     140     213 ..     140     213 .. 0.99

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 3.6
    zf-Mss51 16 dfeCpdC 22
                +++C +C
  EEA18821.1  4 EYTCSRC 10
                799*999 PP

  == domain 2  score: 99.5 bits;  conditional E-value: 1.8e-32
    zf-Mss51   1 lCPvpkhkqt.................apkhvdfeCpdCGiptycseehwedDyeahleicdtLrqvnedeHDL 57 
                 +CP+p+h+qt                 +p+h +feCpdCG+p ycseehw+dD eahl++c+t+rq+ned+HDL
  EEA18821.1 140 FCPHPSHQQTraptgtakdkevatgtlPPAHAHFECPDCGVPLYCSEEHWMDDFEAHLKVCETIRQINEDDHDL 213
                 5************************************************************************9 PP

>> zf-MYND  MYND finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.2     0.095   4.2e+02      12      19 ..       6      13 ..       2      15 .. 0.81
   2 !   18.5   0.4   3.4e-07    0.0015       8      38 .]     170     200 ..     156     200 .. 0.89

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.095
                E-TTTS-S CS
     zf-MYND 12 kCagCksv 19
                 C++C++v
  EEA18821.1  6 TCSRCMQV 13
                7****998 PP

  == domain 2  score: 18.5 bits;  conditional E-value: 3.4e-07
                 B-SCE-TTTS-SEESSHHHHHHCHHHHCCCH CS
     zf-MYND   8 ealkkCagCksvfYCskeCqradwksHkteC 38 
                 +a+  C+ C    YCs+e+   d + H + C
  EEA18821.1 170 HAHFECPDCGVPLYCSEEHWMDDFEAHLKVC 200
                 45559**********************9999 PP

>> zf-HIT  HIT zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   0.1    0.0038        17      12      20 ..       3      11 ..       2      13 .. 0.86
   2 ?    9.0   0.2   0.00029       1.3      12      25 ..     171     185 ..     168     187 .. 0.87

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.0038
                -SEE-TTT- CS
      zf-HIT 12 akYkCpkCn 20
                + Y+C++C 
  EEA18821.1  3 SEYTCSRCM 11
                68******6 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00029
                 -SEE-TTT--E.ESS CS
      zf-HIT  12 akYkCpkCntr.yCS 25 
                 a   Cp C+++ yCS
  EEA18821.1 171 AHFECPDCGVPlYCS 185
                 5678**********9 PP

>> zf_UBZ  Ubiquitin-Binding Zinc Finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.1     0.001       4.6       2      15 ..       4      17 ..       3      19 .. 0.83
   2 ?    2.5   0.8     0.025   1.1e+02       2      12 ..     172     182 ..     171     188 .. 0.75

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.001
      zf_UBZ  2 tylCerCgkeipes 15
                 y+C+rC + + ++
  EEA18821.1  4 EYTCSRCMQVLKPH 17
                69******998765 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.025
      zf_UBZ   2 tylCerCgkei 12 
                 ++ C++Cg ++
  EEA18821.1 172 HFECPDCGVPL 182
                 799****9665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (529 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       557  (0.031067); expected 358.6 (0.02)
Passed bias filter:                      476  (0.0265492); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 3388.88
//
Query:       EEA18822.1  [L=149]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (149 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1417  (0.079034); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.44
# Mc/sec: 1021.66
//
Query:       EEA18823.1  [L=292]
Description: conserved glycine-rich protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (292 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       666  (0.0371465); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.46
# Mc/sec: 1892.76
//
Query:       EEA18824.1  [L=577]
Description: malate dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-93  311.9   0.0    3.7e-93  311.5   0.0    1.2  1  Malic_M   Malic enzyme, NAD binding domain
    9.3e-67  224.3   0.0    1.6e-66  223.6   0.0    1.4  1  malic     Malic enzyme, N-terminal domain
  ------ inclusion threshold ------
       0.18   11.3   0.0       0.31   10.5   0.0    1.2  1  GCHY-1    Type I GTP cyclohydrolase folE2


Domain annotation for each model (and alignments):
>> Malic_M  Malic enzyme, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  311.5   0.0   6.1e-97   3.7e-93       1     257 [.     280     537 ..     280     538 .. 0.98

  Alignments for each domain:
  == domain 1  score: 311.5 bits;  conditional E-value: 6.1e-97
                 THHHHHHHHHHHHHHHHHH-S-GGG--EEEEC-SHHHHHHHHHHHHHHHTT.TS-HHHHHTTEEEEETTEE-BTT-.S---TTTGGGSBS--SS--S.. CS
     Malic_M   1 iqgTaavalagllaalkitgkklseqkivvlGaGsagiGiaeqivealvke.GlseeeakkkiylvDrkGLltedr.ekleeekkpfakkkeelkeakd 97 
                 +qgT++v+la+l+a+l++++++l + +iv++G+G+ag+Gia+qi++a+++e G s+e+a+k+i+++D++GLl++++ +kl++++ p+a++++e +++  
  EEA18824.1 280 VQGTGCVTLAALMAGLHVSKVSLGDVRIVIFGSGTAGTGIADQIRDAIATEsGKSKEQAAKQIWCIDKQGLLFKSHeDKLTPAQIPYAREDSEWEDH-S 377
                 7**********************************************99888**********************99678****************88.8 PP

                 ..SHHHHHHHH--SEEEE-SSSSS-S-HHHHHHHHHHSSS-EEEE--SSGGGSSS-HHHHHHHTTT-SEEEESS----EEETSEEE--EE--GGGTHHH CS
     Malic_M  98 kltLeevvkkvkptvliGlsgvagafteeivremaksterPiilplSNPtskaEataedvlkwtdgkalvasGsPfkpvelngktyeigQaNNayifPg 196
                 +++L +vvk+v+p+vliG+s+ ++af+e+++remak+++rPi++plSNPt+  Ea+++d+ +wtdg+al+a+GsPf+pve+ g++ ei+ +NN+  fPg
  EEA18824.1 378 QTDLYNVVKQVQPHVLIGTSTKPKAFSEDVIREMAKHVDRPIVFPLSNPTRLHEAQPRDLNEWTDGRALIATGSPFPPVEHSGVKKEIAECNNSTCFPG 476
                 9************************************************************************************************** PP

                 HHHHHHHTT-SS--HHHHHHHHHHHHTT--HHHHHTT-SS--GGGHHHHHHHHHHHHHHHH CS
     Malic_M 197 lglgvivarakritdemllaaaealaelvseeelkegsllPelseirevslkvavavakaa 257
                 +glg+++++++ ++d+ml+aa +ala +  + +  +++llP+++++re+s+++a av+++a
  EEA18824.1 477 IGLGAVLSQSRLLSDKMLVAAVKALAAQSPALQDPNKPLLPDVEDVREMSVHIAKAVIQTA 537
                 ******************************999999**********************998 PP

>> malic  Malic enzyme, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  223.6   0.0   2.6e-70   1.6e-66       2     182 .]      87     270 ..      86     270 .. 0.98

  Alignments for each domain:
  == domain 1  score: 223.6 bits;  conditional E-value: 2.6e-70
                 TTECCCCCCHHCCCHHHHHHHHSTTCHHHHHHHHHHHGGCHHSCCCEGGGETCHHHHHTTSS.....SS..EEEEE-SSSBTTTBS-GHHHHHHHHHHH CS
       malic   2 eknetlfykllkekleellpivYtPtvgeacqeyseeyrkarglylsikdkekikeilknlp....eedvkvivvtdgeriLGlGdlGvagvgimvGKl 96 
                  +ne+l+y+l++++l+e+++i+YtPt g+a+q+ys+++rk++g++l+i+d ++i++ lk+++    +edv++ivvtdge iLG+Gd+Gv++v i+v+Kl
  EEA18824.1  87 AQNEVLYYRLIQDHLKEMFSIIYTPTEGDAIQNYSRIFRKPEGCFLNIHDVNRIEHDLKQFTdngtNEDVDYIVVTDGEEILGIGDQGVGSVLISVAKL 185
                 589***************************************************99999887777789******************************* PP

                 HHHHHHHS-EGGGEEEEEECS-BS.HHHHC.TT..S.SSB...SHHHHHHHHHHHHHHHHHHGCTSEEEE-S--CCHHHHHHHHHC CS
       malic  97 aLytalagidPekvlpvvldvgtnneelledplYlGlrkkRvkgeeydefvdefveavkelfppkaliqfEDfkaknafeileryr 182
                 +L t +agi+P++ lpvvld+gt+ne+ll+d+lYlGlr++Rv+geeyd+fvd+fv  ++++f p+a+i+fEDf+ kna +ile+yr
  EEA18824.1 186 VLTTLCAGIHPARQLPVVLDCGTDNEDLLKDELYLGLRHSRVRGEEYDNFVDKFVTSARKIF-PNAYIHFEDFGLKNARRILEKYR 270
                 **************************************************************.9*********************8 PP

>> GCHY-1  Type I GTP cyclohydrolase folE2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   5.2e-05      0.31     192     234 ..     374     416 ..     367     422 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 5.2e-05
                 HHHSSEE--S---HHHHHHHHHHHHTS---HHHHHHHHHHHHH CS
      GCHY-1 192 essassevyellKReDEkavtekayenpkFvEDvvRevaaale 234
                 e++ ++ +y+++K  + + ++ ++ +   F EDv+Re+a++++
  EEA18824.1 374 EDHSQTDLYNVVKQVQPHVLIGTSTKPKAFSEDVIREMAKHVD 416
                 6778999********************************9984 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (577 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       543  (0.0302861); expected 358.6 (0.02)
Passed bias filter:                      523  (0.0291706); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.47
# Mc/sec: 3680.01
//
Query:       EEA18825.1  [L=568]
Description: bZIP transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00012   22.1   2.4    0.00012   22.1   2.4    1.8  2  bZIP_1    bZIP transcription factor
  ------ inclusion threshold ------
       0.29   11.4   9.9      0.061   13.5   5.2    2.1  2  ATG16     Autophagy protein 16 (ATG16)


Domain annotation for each model (and alignments):
>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.1   2.4   1.3e-08   0.00012       7      55 ..      92     140 ..      87     144 .. 0.92
   2 ?   -3.6   0.0       1.4   1.2e+04      37      49 ..     169     181 ..     159     189 .. 0.63

  Alignments for each domain:
  == domain 1  score: 22.1 bits;  conditional E-value: 1.3e-08
                 XXXX--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1   7 ekrkqkNReaArrsRqRKqaeieeLerrvkaLekeNksLkseleelkke 55 
                 e+r+ + R a+r++R RK+a i+ L++r ++L++   ++  ++++ ++e
  EEA18825.1  92 ERRRTQIRLAQRAYRSRKEATISSLSKRLSELDASIREMNTTVGSFRDE 140
                 89********************************999999988888776 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 1.4
                 HHHHHHHHHHHHH CS
      bZIP_1  37 aLekeNksLksel 49 
                 +L++ N+++ s +
  EEA18825.1 169 KLSAANQEYESAN 181
                 4666777776655 PP

>> ATG16  Autophagy protein 16 (ATG16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   5.2   6.8e-06     0.061      69     168 ..      49     149 ..       9     155 .. 0.82
   2 ?   -0.5   0.3      0.13   1.2e+03      24      51 ..     157     187 ..     149     201 .. 0.58

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 6.8e-06
       ATG16  69 nskqsakiqsleqklaqlreelaelyksrgelaqrllelneelqkleeklkedeerlae.leaeraaletklkdreeelrekeklvqdlqDElsaLqlq 166
                 ++++s+   ++++k a   e+ +++ k++      l + +++ ++++++++  +++ ++  ea++++l+++l+++++ +re +++v  ++DEl +  l 
  EEA18825.1  49 TNDKSKPKRNTNNKSAPKSEDDTNVSKRKRGRPRVLDKDENAAERRRTQIRLAQRAYRSrKEATISSLSKRLSELDASIREMNTTVGSFRDELMSSGLL 147
                 3455666778888888889999********99999999999999999****9999998626799*****************************997776 PP

       ATG16 167 ln 168
                 l+
  EEA18825.1 148 LQ 149
                 65 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.13
       ATG16  24 ynrLldrtsaleaenaklekaaasaks...s 51 
                  +rL ++++al + +a+ ++  ++++s   +
  EEA18825.1 157 WQRLVQKSDALVKLSAANQEYESANTSpmdE 187
                 5678888888877777775554444443321 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (568 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       826  (0.0460706); expected 358.6 (0.02)
Passed bias filter:                      457  (0.0254894); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.43
# Mc/sec: 3964.46
//
Query:       EEA18826.1  [L=305]
Description: hypothetical protein PMAA_011040 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (305 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       725  (0.0404373); expected 358.6 (0.02)
Passed bias filter:                      345  (0.0192426); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2169.56
//
Query:       EEA18827.1  [L=769]
Description: membrane bound cation transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      2e-38  131.7  47.3    2.1e-22   79.7  20.1    2.2  2  Na_Ca_ex     Sodium/calcium exchanger protein


Domain annotation for each model (and alignments):
>> Na_Ca_ex  Sodium/calcium exchanger protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.1  19.2   5.2e-20   9.3e-16       3     150 ..     149     304 ..     147     305 .. 0.93
   2 !   79.7  20.1   1.2e-26   2.1e-22       2     150 ..     606     749 ..     605     750 .. 0.86

  Alignments for each domain:
  == domain 1  score: 58.1 bits;  conditional E-value: 5.2e-20
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCTHHHHHHHHHHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHHHTHHHHHHHHHHBTTSSCECCH CS
    Na_Ca_ex   3 fvlfilslllisvladflvssaeeiakslgisgsvlGltllAlgnslpElissiiaaltgevdlaignvlGsnifnlllviGlialigslkvdseslkl 101
                 +v+f +  ++i++la +l  ++e++a   ++ + ++G +l+ +++++ Eli+ iia++ +e+ ++ +++lGs+++nlll++G+++l+g+  + +e+l +
  EEA18827.1 149 TVVFSINAVAIIPLAWMLGYATESVAA--DMGD-TIGALLNVTFGNAVELIIFIIALVADEIAIVQASLLGSILANLLLILGMCFLFGG-LRFREQL-Y 242
                 6888899999****************4..5555.99999**************************************************.7777775.5 PP

                 HHHHHHHHHHHHHHHHHHTCHHHHH.............HTEEHHHHHHHHHHHHHHHHHHHH CS
    Na_Ca_ex 102 dlgllllvallllllvlllllplfv.............pgrltvleglvllllYalylvlsl 150
                 +  ++++ a+ll+l+v+ lllp+++               ++++ +++vlll+Y+lyl+++l
  EEA18827.1 243 NSAVTQMSACLLSLSVISLLLPTAFhasfstianadaaVLKVSRGTSVVLLLVYILYLLFQL 304
                 5559*******************99***********************************98 PP

  == domain 2  score: 79.7 bits;  conditional E-value: 1.2e-26
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCTHHHHHHHHHHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHHHTHHHHHHHHHHBTTSSCECC CS
    Na_Ca_ex   2 lfvlfilslllisvladflvssaeeiakslgisgsvlGltllAlgnslpElissiiaaltgevdlaignvlGsnifnlllviGlialigslkvdseslk 100
                 +++l+++ ++l++v+a+flv+s++++++s+g+s++++Gl++l++++++ E+++++++a ++++dlaig +lGs i++ l+v ++i+l+g++   +    
  EEA18827.1 606 AVILLLVTTALVAVCAEFLVDSIDYLVSSTGVSKAFIGLIILPIVGNAAEHVTAVTVASKNKMDLAIGVALGSSIQIALFVTPVIVLLGWILDTEM--S 702
                 57899************************************************************************************9555554..5 PP

                 HHHHHHHHHHHHHHHHHHHTCHHHHHHTEEHHHHHHHHHHHHHHHHHHHH CS
    Na_Ca_ex 101 ldlgllllvallllllvlllllplfvpgrltvleglvllllYalylvlsl 150
                 l ++l+ +++l+++++++  +l+l  +gr ++leg++l+++Y++++v ++
  EEA18827.1 703 LYFSLFETISLFASAFIVN-YLML--DGRSNYLEGALLIAAYVIIAVSAY 749
                 5555556655555444444.3333..3*****************999765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (769 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1331  (0.0742373); expected 358.6 (0.02)
Passed bias filter:                      576  (0.0321267); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.76u 0.31s 00:00:01.07 Elapsed: 00:00:00.48
# Mc/sec: 4830.30
//
Query:       EEA18828.1  [L=324]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (324 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       360  (0.0200792); expected 358.6 (0.02)
Passed bias filter:                      314  (0.0175135); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.46
# Mc/sec: 2122.65
//
Query:       EEA18829.1  [L=359]
Description: Ras family GTPase (Rab4b), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-39  135.5   0.0    7.2e-39  133.0   0.0    1.9  1  Ras              Ras family
    1.4e-28   99.5   0.0    2.4e-28   98.8   0.0    1.4  1  Roc              Ras of Complex, Roc, domain of DAPkinase
    1.2e-10   41.1   0.0    5.7e-10   38.9   0.0    1.8  2  Arf              ADP-ribosylation factor family
    2.5e-06   27.0   0.0    4.1e-06   26.3   0.0    1.3  1  Gtr1_RagA        Gtr1/RagA G protein conserved region
    4.6e-06   26.3   0.0    2.6e-05   23.9   0.0    1.9  1  GTP_EFTU         Elongation factor Tu GTP binding domain
    0.00021   21.3   0.0    0.00038   20.5   0.0    1.5  1  MMR_HSR1         50S ribosome-binding GTPase
    0.00058   19.8   0.0      0.038   13.9   0.0    2.4  2  RsgA_GTPase      RsgA GTPase
     0.0018   17.8   0.0     0.0042   16.6   0.0    1.6  2  SRPRB            Signal recognition particle receptor beta su
     0.0034   17.2   0.1      0.019   14.7   0.0    1.9  2  ATP_bind_1       Conserved hypothetical ATP binding protein
  ------ inclusion threshold ------
      0.013   15.7   0.0      0.025   14.7   0.0    1.6  1  AAA_33           AAA domain
      0.013   15.4   0.0        0.2   11.6   0.0    2.2  2  NACHT            NACHT domain
      0.017   14.6   0.0      0.031   13.8   0.0    1.3  1  AAA_7            P-loop containing dynein motor region
      0.019   15.2   0.0      0.032   14.5   0.0    1.4  1  AAA_28           AAA domain
      0.028   14.8   0.1      0.065   13.6   0.0    1.7  2  AAA_16           AAA ATPase domain
      0.033   14.5   0.1      0.088   13.1   0.0    1.8  2  AAA_22           AAA domain
      0.052   13.6   0.0       0.18   11.8   0.0    1.9  2  AAA_5            AAA domain (dynein-related subfamily)
       0.06   13.9   0.0       0.15   12.6   0.0    1.6  1  ABC_tran         ABC transporter
      0.077   12.7   0.0       0.45   10.2   0.0    2.1  2  PduV-EutP        Ethanolamine utilisation - propanediol utili
       0.14   12.6   0.0       0.57   10.6   0.0    2.1  1  AAA              ATPase family associated with various cellul
       0.16   11.7   0.0        0.3   10.8   0.0    1.4  1  Sigma54_activat  Sigma-54 interaction domain
       0.17   11.6   0.6        0.7    9.6   0.0    2.1  3  AAA_24           AAA domain


Domain annotation for each model (and alignments):
>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  133.0   0.0   8.4e-42   7.2e-39       1     161 [.      32     266 ..      32     267 .. 0.97

  Alignments for each domain:
  == domain 1  score: 133.0 bits;  conditional E-value: 8.4e-42
                 EEEEEESTTSSHHHHHHHHHHSSCSSSCTTTSSEEEEEEEEEET....TEEEEEEEEEETTSGGGHHHHHHHHTTESEEEEEEETTBHHHHHTHHHHHH CS
         Ras   1 KlvlvGdsavGKtslllrfvkdkFkeeyesTigvdfytkeievd....gkevkleiwDTAGqeefkslrelyyrdaegillvyditsresfenvkkwve 95 
                 K++l+G s++GK++ll+rfvkd+++  + +Tigv+f +k +++      k++kl++wDTAG e+f+s+ ++yyr+a g++lvyd++s +sf  +++++ 
  EEA18829.1  32 KVILIGPSGTGKSCLLHRFVKDEWRVLSSQTIGVEFSSKIVKIGtgsrRKRIKLQLWDTAGTERFRSVSRSYYRGAAGAVLVYDVSSYTSFAALSTFLM 130
                 89****************************************99888899************************************************* PP

                 HHHHHSTTTSEEEEEEETTTGGG.....................................................................G-SS-HH CS
         Ras  96 eikrvaeenvpivLvGnKvDlee.....................................................................kravste 125
                 + +  a+ n++ +L GnKvDl                                                                        r+vs  
  EEA18829.1 131 DARALASPNLTTILAGNKVDLLAdddqteivdtededvpssmsiansvsssknsssymfdgivrkggagslrsvtstnfaagtrltattnshGRQVSDL 229
                 *********************9999*******************************************************************9****** PP

                 HHHHHHHHHTSE.EEEEBTTTTCTHHHHHHHHHHHHH CS
         Ras 126 egeelakelglk.fletSAktnenveeafeellreil 161
                 e+ e+a + +++  +e+SA + +nv+e+f++l+r il
  EEA18829.1 230 EAIEWATRSNIPvAVEVSAFSGQNVDELFTRLARIIL 266
                 **********76269*****************99875 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.8   0.0   2.8e-31   2.4e-28       1     120 []      32     151 ..      32     151 .. 0.89

  Alignments for each domain:
  == domain 1  score: 98.8 bits;  conditional E-value: 2.8e-31
                 EEEEESSTTSSHHHHHHCHCT-CCC-EEETTTTEEEEEEECGGSGGCTTBTTTTCEEEEEEEE-SGGCTTTT-HHHHCTSCEEEEEEE...GHHHHCHH CS
         Roc   1 KvvlvGdsgvGKtsllkrfvedkfsekekstigvdfltkevtkikgvendkkvkkvklniWDtaGqerfrslhplylreaalailvyd...srssenlk 96 
                 Kv+l+G sg+GK++ll+rfv+d+ +  +++tigv+f++k v ki +    ++ k++kl++WDtaG erfrs+ ++y+r+aa a+lvyd    +s++ l+
  EEA18829.1  32 KVILIGPSGTGKSCLLHRFVKDEWRVLSSQTIGVEFSSKIV-KIGT---GSRRKRIKLQLWDTAGTERFRSVSRSYYRGAAGAVLVYDvssYTSFAALS 126
                 9***********************************99865.5554...456789*********************************6544467899* PP

                 HHHHHHHHHCS.SS-EEEEEE-TTT CS
         Roc  97 eWlkelkkvag.kspvilvgnkiDl 120
                 + l + ++ a+ +   il gnk+Dl
  EEA18829.1 127 TFLMDARALASpNLTTILAGNKVDL 151
                 ********988355899******95 PP

>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.9   0.0   6.7e-13   5.7e-10      15     138 ..      31     162 ..      20     192 .. 0.83
   2 ?   -0.4   0.0      0.79   6.7e+02     134     173 ..     221     263 ..     214     265 .. 0.65

  Alignments for each domain:
  == domain 1  score: 38.9 bits;  conditional E-value: 6.7e-13
                 EEEEEEESTTSSHHHHHHHHHHSSCEE.CSSSSS..EEEEEEEE......TTEEEEEEEE-SSGGGGGGGGGGCTTESEEEEEEETT-CTTHHHHHHHH CS
         Arf  15 lrilllGLDnaGKtTilkklkleelvt.tvPTig..fnveelei......knlkftvwDvGGqeklRplWknYfektdavifvvDsadreRleeakeeL 104
                 ++++l+G  ++GK+ +l+++ ++e     + Tig  f ++ ++i      k +k+++wD  G e+ R++ ++Y++   + + v D++  + ++  ++ L
  EEA18829.1  31 AKVILIGPSGTGKSCLLHRFVKDEWRVlSSQTIGveFSSKIVKIgtgsrrKRIKLQLWDTAGTERFRSVSRSYYRGAAGAVLVYDVSSYTSFAALSTFL 129
                 799******************999876456677633677888889999999**************************************9998877655 PP

                 HHHCTSGCCT..TSEEEEEEE-TTSTTSS-HHHHHH CS
         Arf 105 kalleeeelk..evallvlaNKqDlpealseeelre 138
                    ++ + l+  + + ++ +NK Dl  + +++e+ +
  EEA18829.1 130 ---MDARALAspNLTTILAGNKVDLLADDDQTEIVD 162
                 ...44555554477888999*****99988888765 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.79
                 HHHHHHTTGGGSS....SSSSEEEEEEBTTTTBTHHHHHHHHHH CS
         Arf 134 eelrellgleelk....gkrkleiqkcsavkgeglkeglewlse 173
                 ++ r+  +le ++    ++ ++  +++sa +g++++e +++l++
  EEA18829.1 221 SHGRQVSDLEAIEwatrSNIPVA-VEVSAFSGQNVDELFTRLAR 263
                 55555666666664422333333.47899**********99986 PP

>> Gtr1_RagA  Gtr1/RagA G protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.3   0.0   4.8e-09   4.1e-06       1     148 [.      32     176 ..      32     192 .. 0.75

  Alignments for each domain:
  == domain 1  score: 26.3 bits;  conditional E-value: 4.8e-09
   Gtr1_RagA   1 kvLLmGksgsGKtsmrs.iiFdn..ylardtlrlgatidveksev.rflgnltlnlwDcgGqeafveeylssqkeeifrnvgvliyVfDvesreleedl 95 
                 kv+L+G+sg GK+++    + d+  +l  +t+ ++ ++++ k       + ++l+lwD  G+e+f   +      + +r  +  + V Dv+s     +l
  EEA18829.1  32 KVILIGPSGTGKSCLLHrFVKDEwrVLSSQTIGVEFSSKIVKIGTgSRRKRIKLQLWDTAGTERFRSVS-----RSYYRGAAGAVLVYDVSSYTSFAAL 125
                 89************86505555433678888888888887665441567889************98875.....44455555556677***66666666 PP

   Gtr1_RagA  96 etlkeilealrqyspeakvfvlihKmDliqedereeifeerkeeireeiekle 148
                 +t+    +a    sp+++     +K+Dl+++d ++ei++++ e++ + ++ ++
  EEA18829.1 126 STFLM--DARALASPNLTTILAGNKVDLLADDDQTEIVDTEDEDVPSSMSIAN 176
                 66654..4445579****99999*******************99988877544 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.0     3e-08   2.6e-05      64     190 ..      68     263 ..      29     267 .. 0.77

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 3e-08
                 E.........TTCSSEEEEEEEESSSGGGHHHHHHHHHT-SEEEEEEETTTBST.HHHHHHHHHHHHTTTE...EEEEEESCGST.HHHHHHHHHHHHH CS
    GTP_EFTU  64 e.........ketkkylinliDtPGHvdFskevirglrvlDgavlvvdaveGve.pqteevlrlalkegvp...iivfiNKmDrl.kaelkeiveevkq 148
                 +         ++ k+ +++l Dt G + F +     +r + gavlv d+++    +   + l  a+++  p   +i++ NK+D l +++  eiv++  +
  EEA18829.1  68 SskivkigtgSRRKRIKLQLWDTAGTERFRSVSRSYYRGAAGAVLVYDVSSYTSfAALSTFLMDARALASPnltTILAGNKVDLLaDDDQTEIVDTEDE 166
                 3344444454588999*************9877777*************98754145566677777776666669**********98888999999998 PP

                 HHHHH......................................................HHHHHHHHHTTTTTEEE.EEEBTTTTBTHHHHHHHHHH CS
    GTP_EFTU 149 klsrk......................................................eeklekygekgekevpv.vfgSalkgegvktllealve 190
                 ++ ++                                                       ++le+++  +++++pv v +Sa++g++v++l+  l +
  EEA18829.1 167 DVPSSmsiansvsssknsssymfdgivrkggagslrsvtstnfaagtrltattnshgrqVSDLEAIEWATRSNIPVaVEVSAFSGQNVDELFTRLAR 263
                 88666788888889888888888888888888888888888888888877777777776555555533333677773679**********9988776 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5   0.0   4.5e-07   0.00038       1      86 [.      32     117 ..      32     163 .. 0.69

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 4.5e-07
                 EEEEEESTTSSHHHHHHHHHTS..TEEESSSTTSSSSEEEEEEE....ETTEEEEEEECGGCSSHHHHHHHHHHHHHHHHCTSEEEEEEETT CS
    MMR_HSR1   1 evaivGrpNvGKStLinaltge..kaivsdkpgtTrdinegrvk....lkgkeielvDtpGliegaseekglgkaflaleeadlillvvdas 86 
                 +v+++G + +GKS L+ + +++  ++  s++ g+    +  ++      k+ +++l+Dt+G  e   + +++++++ +   a  ++lv d+s
  EEA18829.1  32 KVILIGPSGTGKSCLLHRFVKDewRVLSSQTIGVEFSSKIVKIGtgsrRKRIKLQLWDTAG-TE---RFRSVSRSYYR--GAAGAVLVYDVS 117
                 689******************85656666666555555444444444444488********.66...33366666664..366777777755 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   0.0   4.4e-05     0.038      88     122 ..      21      53 ..       6      85 .. 0.77
   2 ?    3.5   0.0     0.072        61      22      73 ..     113     166 ..      93     186 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 4.4e-05
                  TTHHHHHHHCTTSEEEEECSTTSSHHHHHHHHCTT CS
  RsgA_GTPase  88 egleelkellkdktsvlvGqSGvGKStLinallpe 122
                  ++le++ ++l    ++l+G+SG GKS L+ +++ +
   EEA18829.1  21 QELESMYDYL--AKVILIGPSGTGKSCLLHRFVKD 53 
                  3444444444..4589*************998775 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.072
                  EEESTTTT--HHHHHHHHHHHH...HTT-EEEEEEE-GGG--HHHHHHHHHHHHH CS
  RsgA_GTPase  22 vvslkepelslnlldrfLvlae...ekgiepvivlnKiDlleeeeeleelkeele 73 
                  v  ++   +s   l+ fL+ a    + +++ +++ nK+Dll +++++e + +e e
   EEA18829.1 113 VYDVS-SYTSFAALSTFLMDARalaSPNLTTILAGNKVDLLADDDQTEIVDTEDE 166
                  55555.55666777777776541115678999999********996666555544 PP

>> SRPRB  Signal recognition particle receptor beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   4.9e-06    0.0042       5      65 ..      32      99 ..      28     163 .. 0.73
   2 ?   -2.5   0.0       3.4   2.9e+03      26      46 ..     165     185 ..     148     208 .. 0.69

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 4.9e-06
                EEEEE-STTSSHHHHHHHHHHS..S---B---SS-EEETTG.........GGTT-SEEEETT-GCCSHH CS
       SRPRB  5 avllvGlsdsGKTslftrLttd..svkktvtSqessaalkv......ksekgskltliDfPGheklrqk 65
                +v+l+G+s +GK  l++r  +d   v +++t +  +++ k+      + +k  kl+l D  G e++r+ 
  EEA18829.1 32 KVILIGPSGTGKSCLLHRFVKDewRVLSSQT-IGVEFSSKIvkigtgSRRKRIKLQLWDTAGTERFRSV 99
                79********************552223332.334444444444766677888999**********974 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 3.4
                 SS---B---SS-EEETTG... CS
       SRPRB  26 dsvkktvtSqessaalkvkse 46 
                 d+  ++ +S+++s++ + +s+
  EEA18829.1 165 DEDVPSSMSIANSVSSSKNSS 185
                 556667777777766655333 PP

>> ATP_bind_1  Conserved hypothetical ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.0      0.67   5.8e+02       2      17 ..      36      51 ..      35      62 .. 0.88
   2 !   14.7   0.0   2.2e-05     0.019      92     187 ..      84     170 ..      59     194 .. 0.76

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.67
  ATP_bind_1  2 vGpaGsGKttfvgals 17
                +Gp G GK+ + ++++
  EEA18829.1 36 IGPSGTGKSCLLHRFV 51
                8********9998775 PP

  == domain 2  score: 14.7 bits;  conditional E-value: 2.2e-05
  ATP_bind_1  92 dyllfDtPGQielfthseslakiveeLesefalvvvyLvDsqrltdptkfisgllsalsamlrlelPhvvvlnkfDllkeklekeleffedveals 187
                 ++ l Dt G  ++  +s s          ++a ++v + D+   t+    +s+ l+  +a+++ +l+++ + nk+Dll+++++ e+   ed +  s
  EEA18829.1  84 KLQLWDTAGTERFRSVSRSYY--------RGAAGAVLVYDVSSYTS-FAALSTFLMDARALASPNLTTILAGNKVDLLADDDQTEIVDTEDEDVPS 170
                 777778888878777777777........99***********9999.6678999*************************99777776666655444 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   0.0   2.9e-05     0.025       2      32 ..      33      62 ..      33     136 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 2.9e-05
      AAA_33  2 vllvGlpGsGKstlaerllkklgavllssdt 32
                v+l+G++G+GKs l++r + k  + +lss t
  EEA18829.1 33 VILIGPSGTGKSCLLHRFV-KDEWRVLSSQT 62
                799**************99.66788888777 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   0.00023       0.2       3      23 ..      33      53 ..      31      67 .. 0.87
   2 ?    1.4   0.0       0.3   2.6e+02     109     161 ..     201     260 ..     184     263 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00023
                EEEEC-TTTCHHHHHHHHHHH CS
       NACHT  3 vilqGeaGsGKTtLlqklala 23
                vil G++G GK+ Ll++++ +
  EEA18829.1 33 VILIGPSGTGKSCLLHRFVKD 53
                89***************9975 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.3
                 HHHHHCTTTTT--EEEEEEECCCHHH.HCTTSSCE...........EEEE--TCCHHHHHHHH CS
       NACHT 109 Lselirkkllpeasllltvrpralrd.leeqleea.........ivlevegfsesrrkqlvrk 161
                 L++  + +   +++l +t+ + +++    e                +ev +fs +++++l+ +
  EEA18829.1 201 LRSVTSTNFAAGTRLTATTNSHGRQVsDLEA---IewatrsnipVAVEVSAFSGQNVDELFTR 260
                 5666666666777777777777774342222...223366678899*************9976 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   3.6e-05     0.031      29      71 ..      26      69 ..      20      75 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 3.6e-05
       AAA_7 29 llknkkpvllvGptGtGKtviikd.llkkldkekylsltinfsa 71
                + +   +v+l+Gp+GtGK++++++ + ++    + +++ ++fs+
  EEA18829.1 26 MYDYLAKVILIGPSGTGKSCLLHRfVKDEWRVLSSQTIGVEFSS 69
                55666789****************55555566666777777776 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.0   3.8e-05     0.032       1      94 [.      32     130 ..      32     166 .. 0.65

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 3.8e-05
      AAA_28   1 kivitGgestGKTtlleaLaargypvv......pEaareileeklakgedalpwvedllafaervleeqleeeaaa....aankvlfcDrglldtlaYa 89 
                 k++++G+++tGK+ ll ++ +++++v+       E+  +i++ ++ ++++ ++     l++ +    e+ +   +     aa+ vl++D ++ +++a +
  EEA18829.1  32 KVILIGPSGTGKSCLLHRFVKDEWRVLssqtigVEFSSKIVKIGTGSRRKRIK-----LQLWDTAGTERFRSVSRSyyrgAAGAVLVYDVSSYTSFAAL 125
                 799*****************996665444111556666666666655554443.....33333333333333322223337888888888888888877 PP

      AAA_28  90 raygg 94 
                  ++  
  EEA18829.1 126 STFLM 130
                 65544 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.0   7.6e-05     0.065      27      61 ..      33      63 ..      16     161 .. 0.75
   2 ?   -2.9   0.0       9.2   7.8e+03     106     127 ..     243     265 ..     198     279 .. 0.61

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 7.6e-05
      AAA_16 27 vllsGesGvGKsslvrellralekdggiflrgkcd 61
                v+l+G+sG+GKs l+ ++ +    d++ +l+ ++ 
  EEA18829.1 33 VILIGPSGTGKSCLLHRFVK----DEWRVLSSQTI 63
                79*************77764....55777665554 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 9.2
      AAA_16 106 a.avpelagaeasrllellkrll 127
                 a +v++ +g+    l+  l+r++
  EEA18829.1 243 AvEVSAFSGQNVDELFTRLARII 265
                 24455555555555555555554 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0    0.0001     0.088       9      28 ..      34      53 ..      31      99 .. 0.85
   2 ?   -2.9   0.0       8.7   7.4e+03      44      63 ..     245     264 ..     224     269 .. 0.59

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 0.0001
      AAA_22  9 vvtGesGtGKTtllrrlleq 28
                +++G+sGtGK+ ll r+++ 
  EEA18829.1 34 ILIGPSGTGKSCLLHRFVKD 53
                89**************9985 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 8.7
      AAA_22  44 fvtlpsstsskdllrellra 63 
                 +v + s+ + ++l+++l+r+
  EEA18829.1 245 EVSAFSGQNVDELFTRLARI 264
                 45555555666666666554 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   0.00021      0.18       2      19 ..      33      50 ..      32      59 .. 0.91
   2 ?   -2.6   0.0       5.8     5e+03     110     130 ..     209     229 ..     195     232 .. 0.68

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00021
                EEEE--SSSSHHHHHHHG CS
       AAA_5  2 vlLvGppGtgKselaerl 19
                v+L+Gp+GtgKs l  r+
  EEA18829.1 33 VILIGPSGTGKSCLLHRF 50
                9***********999886 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 5.8
                 ....-EEEEEESS--.-TT-T CS
       AAA_5 110 llerfrviatanpldrslnel 130
                 ++  +r+ at+n+  r++++l
  EEA18829.1 209 FAAGTRLTATTNSHGRQVSDL 229
                 555588888999888888776 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   0.00017      0.15      13      36 ..      32      55 ..      26     105 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 0.00017
                EEEEEESTTSSHHHHHHHHTTSS- CS
                xxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran 13 kvaivGenGaGKStLlkllagllk 36
                kv ++G++G+GKS Ll  + + + 
  EEA18829.1 32 KVILIGPSGTGKSCLLHRFVKDEW 55
                799*************98877665 PP

>> PduV-EutP  Ethanolamine utilisation - propanediol utilisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   0.00053      0.45       3      40 ..      32      71 ..      30      77 .. 0.78
   2 ?   -0.8   0.0       1.3   1.1e+03     123     141 ..     243     261 ..     225     263 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00053
   PduV-EutP  3 killiGkvgsGKttLtqalkgeelkYkktqai..efsdev 40
                k++liG++g+GK  L +++ ++e +  + q+i  efs+++
  EEA18829.1 32 KVILIGPSGTGKSCLLHRFVKDEWRVLSSQTIgvEFSSKI 71
                9***************999888877766666422666655 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 1.3
   PduV-EutP 123 ifevsavekegieellkyl 141
                   evsa + ++++el++ l
  EEA18829.1 243 AVEVSAFSGQNVDELFTRL 261
                 4799***********9987 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00067      0.57       1      33 [.      33      69 ..      33     157 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00067
                EEEESSTTSSHHHHHHHHHHH....HTHEEEEEETTT CS
         AAA  1 vllyGppGtGKTllakavake....lgvefleisgse 33
                v+l+Gp GtGK+ l +  +k+    l+++ + ++ s+
  EEA18829.1 33 VILIGPSGTGKSCLLHRFVKDewrvLSSQTIGVEFSS 69
                68**********9999888875555344443333333 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00035       0.3       7      41 ..      15      49 ..      10      67 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00035
                     HHHHHHHHHHHHCTSSS-EEEECSTTSSHHHHHHH CS
  Sigma54_activat  7 alkelleqikkvaktdlsvlitGesGtGKellara 41
                     +l +  ++++++ ++ ++v++ G sGtGK++l + 
       EEA18829.1 15 SLPDRNQELESMYDYLAKVILIGPSGTGKSCLLHR 49
                     56666788999999***************987655 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.0   0.00082       0.7       3      22 ..      31      50 ..      30      71 .. 0.86
   2 ?   -2.8   0.0         5   4.3e+03     134     196 ..     159     214 ..     156     215 .. 0.60
   3 ?   -1.1   0.1       1.5   1.3e+03      87     111 ..     324     348 ..     307     351 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00082
      AAA_24  3 lkiliyGpsgiGKTtlakel 22
                +k++++Gpsg+GK+ l+ ++
  EEA18829.1 31 AKVILIGPSGTGKSCLLHRF 50
                589************99998 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 5
      AAA_24 134 rkdedpegeakytrlepklgkktanelkeevDlvlranlkredkvgervlktsksesidaKnR 196
                 + +++++++ +    + +  + ++n   +++D ++r       k+g   l   +s+++ a++R
  EEA18829.1 159 EIVDTEDEDVPSSMSIANSVSSSKNSSSYMFDGIVR-------KGGAGSLRSVTSTNFAAGTR 214
                 555555555444444455555558888888888887.......55666666777777777766 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 1.5
      AAA_24  87 rqnekaeskedkgdgkGygelaeef 111
                 r+n++ ++++ +++ + +ge+++ f
  EEA18829.1 324 RNNNNNNNNNNNNSNNSWGEWGDVF 348
                 5555556667777778899988876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (359 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       602  (0.0335769); expected 358.6 (0.02)
Passed bias filter:                      419  (0.02337); expected 358.6 (0.02)
Passed Vit filter:                        70  (0.00390429); expected 17.9 (0.001)
Passed Fwd filter:                        21  (0.00117129); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              21  [number of targets reported over threshold]
# CPU time: 0.59u 0.34s 00:00:00.93 Elapsed: 00:00:00.50
# Mc/sec: 2176.99
//
Query:       EEA18830.1  [L=381]
Description: xylitol dehydrogenase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      2e-33  114.5   0.1    4.1e-33  113.5   0.1    1.5  1  ADH_N            Alcohol dehydrogenase GroES-like domain
    8.2e-24   84.0   0.2    1.3e-23   83.4   0.2    1.3  1  ADH_zinc_N       Zinc-binding dehydrogenase
    2.4e-09   37.0   0.5    6.9e-09   35.5   0.3    1.8  2  Glu_dehyd_C      Glucose dehydrogenase C-terminus
    0.00012   23.1   0.1    0.00027   22.0   0.1    1.7  1  ADH_zinc_N_2     Zinc-binding dehydrogenase
    0.00035   19.9   0.8    0.00056   19.3   0.8    1.2  1  AlaDh_PNT_C      Alanine dehydrogenase/PNT, C-terminal domain
  ------ inclusion threshold ------
      0.012   15.2   0.0       0.02   14.4   0.0    1.3  1  UDPG_MGDP_dh_N   UDP-glucose/GDP-mannose dehydrogenase family
      0.023   13.9   0.3       0.07   12.4   0.4    1.8  2  Pyr_redox_2      Pyridine nucleotide-disulphide oxidoreductas
      0.031   15.0   0.1      0.056   14.2   0.1    1.5  1  Methyltransf_25  Methyltransferase domain
      0.039   13.3   0.0      0.077   12.3   0.0    1.5  1  2-Hacid_dh_C     D-isomer specific 2-hydroxyacid dehydrogenas
      0.078   11.7   0.1       0.11   11.1   0.1    1.2  1  HI0933_like      HI0933-like protein
       0.16   12.1   0.8       0.33   11.0   0.5    1.7  2  AdoHcyase_NAD    S-adenosyl-L-homocysteine hydrolase, NAD bin


Domain annotation for each model (and alignments):
>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.5   0.1   2.5e-36   4.1e-33       3     109 .]      61     170 ..      59     170 .. 0.97

  Alignments for each domain:
  == domain 1  score: 113.5 bits;  conditional E-value: 2.5e-36
                 EEEEEEEEEEE-HHHHHHHTTS..TTTTSSSSEE---EEEEEEEEESTT-CS--TT-EEEE-SEEE-SSSHHHHTT-GGG-TTBEETTTS.S-SSSBSE CS
       ADH_N   3 evlikvkaagiCgsDlhilkgg..kelevklplilGHEivGeveevgpevkklkvGdrVvvepliscgeCaaCkegeenlCeeakllgvs.ldGgfaey 98 
                 +vli+vk++giCgsD+h++++g   ++ v+ p++lGHE +G+v++vg++v++lkvGd+V++ep i+c +C+ Ck+g+++lC ++++  +  +dG++a+y
  EEA18830.1  61 DVLINVKYTGICGSDVHYWEHGaiGSFVVREPMVLGHESSGIVSKVGSKVTTLKVGDQVAMEPGIPCRRCEPCKSGKYHLCINMAFAATPpYDGTLARY 159
                 8********************9888999*************************************************************99******** PP

                 EEECGGGEEEE CS
       ADH_N  99 vvvpekklvkl 109
                 + +pe++++kl
  EEA18830.1 160 YRLPEDFCYKL 170
                 ********986 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.4   0.2   7.7e-27   1.3e-23       1     129 [.     210     342 ..     210     343 .. 0.95

  Alignments for each domain:
  == domain 1  score: 83.4 bits;  conditional E-value: 7.7e-27
                 HHHHHHHHHHHHTT-.EEEEEESSHHHHHHHHHTTESEEEET......TTC.HHHHHHHHHTTTSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSCT CS
  ADH_zinc_N   1 gvGlaavqlAkalGa.eviavdsseeklelakklGadeviny......kea.dlverikeltggegvdvvfecvGsgatleaalkllkpgGrlvvvGgg 91 
                 +vGl+ +++Aka+Ga +vi+ d+++++l++akk+ ad ++ +      ++a +l+e+  +l    g+dvv+e++G++ ++ + + +l+ gG++v  G+g
  EEA18830.1 210 PVGLLCCAVAKAFGAsKVIVSDIQQSRLDFAKKYIADGTFQParvsaeENAnRLKEEHDMLA---GADVVLEASGAEPAIHTGVHVLRTGGTFVQAGMG 305
                 7*******************************************999877767888888888...9********************************9 PP

                 SSEEEEEHHHHHHTT-EEEEE-SSCHHHHHHHHHHHHH CS
  ADH_zinc_N  92 kgeeefdlrnlllkeksilGsllgslreefkealdlla 129
                 k e  f+++ +  ke++++Gs++++ + ++k a++l+a
  EEA18830.1 306 KSEMNFPIMAVCGKELNFKGSFRYG-SGDYKLAVELVA 342
                 99999********************.*******99987 PP

>> Glu_dehyd_C  Glucose dehydrogenase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       3.3   5.4e+03     147     165 ..       7      25 ..       3      28 .. 0.77
   2 !   35.5   0.3   4.2e-12   6.9e-09      24     210 ..     193     378 ..     177     379 .. 0.71

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 3.3
  Glu_dehyd_C 147 relvleNkalvGsvNanrr 165
                  +  + +N +l+G + a +r
   EEA18830.1   7 QLSWRDNSLLIGNTSATIR 25 
                  5568899999999988876 PP

  == domain 2  score: 35.5 bits;  conditional E-value: 4.2e-12
  Glu_dehyd_C  24 rsafewepesalvlGaGslGLLalalleaeerglervyvlg.rrdrpdptidlveelGatYv......dsretpvdeipeaseemdlvvEaTGsakha 114
                  r+      +s++v GaG++GLL  a+ +a   g ++v v + +++r d + + +++  +t+       +++ + ++e  ++    d+v+Ea G+ +++
   EEA18830.1 193 RQGNIVPGSSVVVFGAGPVGLLCCAVAKA--FGASKVIVSDiQQSRLDFAKKYIAD--GTFQparvsaEENANRLKEEHDMLAGADVVLEASGAEPAI 286
                  333445567899***********888875..6888898888445555666665553..444411101133344566666677789************* PP

  Glu_dehyd_C 115 feaiealapnGvaaLlGvpedsevevdggelhrelvleNkalvGsvNanrrhfeaavdtLaalpeslldelvtkvvdldeleeAfeddd..etiKtvv 210
                     ++ l++ G  + +G+ +++ +++ + ++  +         Gs       ++ av+ +a + +  ++el+t++ +++++e+A+ d +  + iKt++
   EEA18830.1 287 HTGVHVLRTGGTFVQAGMGKSE-MNFPIMAVCGK----ELNFKGSFRYGSGDYKLAVELVA-TGKISVKELITGEFKFEDAEQAYVDVKagKGIKTII 378
                  ******************9876.55555555433....3344599999999******8665.5566789****************8654337899987 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.0   0.1   1.6e-07   0.00027      20     126 ..     270     372 ..     222     374 .. 0.78

  Alignments for each domain:
  == domain 1  score: 22.0 bits;  conditional E-value: 1.6e-07
                   TT-EEEEEES-HHHHH.HHHHHHEEEEEEEEE--.--..S-EEE-CHHHCTTT-EEEE--GGG...-.-HHHHHHHHHHHHHHH..----EEEEEEG CS
  ADH_zinc_N_2  20 gegvDvvldtvggealleaslkvlpggGrlvsig.gpp.lsaallkpakkrkgrsvkyeflfsmkasaqadileelaalieeGk..lrpvvdrvfpl 112
                    +g Dvvl++ g e +++  ++vl+ gG++v+ g g++ + + ++++    k+ ++k +f      +   d  +  ++l++ Gk  ++  ++ +f++
    EEA18830.1 270 LAGADVVLEASGAEPAIHTGVHVLRTGGTFVQAGmGKSeMNFPIMAVCG--KELNFKGSFRY----G-SGD-YKLAVELVATGKisVKELITGEFKF 358
                   4789********88888*******999******9775544444444444..33555554444....3.455.899*********4445579999*** PP

                   GGHHHHHHHHHSS- CS
  ADH_zinc_N_2 113 eeaaeAhrylesgr 126
                   e+a +A+ ++++g+
    EEA18830.1 359 EDAEQAYVDVKAGK 372
                   ********999986 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.8   3.4e-07   0.00056      26      98 ..     198     273 ..     186     292 .. 0.78

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 3.4e-07
                  B---EEEEESTSHHHHHHHHHHHHTT-.EEEEEESSHHHHHHHHH..TTTCECEEHCHHHHHHHHHHHH-SEEEE- CS
  AlaDh_PNT_C  26 vepakvlviGgGvaGlqAiatakglga.kVtvlDvrparleqles..lgakfvevlksqeellaeavkeadvvigt 98 
                  v  + v+v+G+G +Gl   a+ak++ga kV v D++++rl   ++    ++f  ++ s ee+ ++  +e d++ g+
   EEA18830.1 198 VPGSSVVVFGAGPVGLLCCAVAKAFGAsKVIVSDIQQSRLDFAKKyiADGTFQPARVSAEENANRLKEEHDMLAGA 273
                  45789*********************957************99997555565555666666666666666776665 PP

>> UDPG_MGDP_dh_N  UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   1.3e-05      0.02       3      38 ..     203     239 ..     201     252 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.3e-05
                     EEEE--STTHHHHHHHHHHCT.SEEEEE-S-HHHHHH CS
  UDPG_MGDP_dh_N   3 isviGlGYvGlvtaavlaeig.hevigvDideekvdk 38 
                     ++v+G+G vGl ++av  + g  +vi+ Di++++ d 
      EEA18830.1 203 VVVFGAGPVGLLCCAVAKAFGaSKVIVSDIQQSRLDF 239
                     89***************9999899********99885 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0         1   1.7e+03     154     178 ..      96     120 ..      94     126 .. 0.80
   2 ?   12.4   0.4   4.3e-05      0.07     142     173 ..     199     231 ..     147     302 .. 0.78

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1
                  HHHHHHHHHHHT-EEEEEESSSSSS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 154 GvElAaalaklgkevtlveardrll 178
                  G E ++  +k+g++vt ++ +d++ 
   EEA18830.1  96 GHESSGIVSKVGSKVTTLKVGDQVA 120
                  7788899999999999999999886 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 4.3e-05
                  T.SEEEEES-SHHHHHHHHHHHHHT-EEEEEES CS
                  x.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 142 p.krivvvGgGyiGvElAaalaklgkevtlvea 173
                  p  ++vv G+G++G+ ++a+++ +g+  ++v +
   EEA18830.1 199 PgSSVVVFGAGPVGLLCCAVAKAFGASKVIVSD 231
                  15789*******************996444433 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.1   3.4e-05     0.056       4      67 ..     206     269 ..     203     297 .. 0.64

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 3.4e-05
                      ET-TT.SHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHHTTT.TEEE.EESBCCGBSSSTTTEEE CS
  Methyltransf_25   4 lGcGt.GrltlalakrlgkakvtgvDiseemleaareraeeegl.nvef.vqgdaedlpfedgsfDl 67 
                      +G+G+ G l+ a+ak++g++kv+  Di+++ l+ a++ +++  +  +++  + +a++l++e    D+
       EEA18830.1 206 FGAGPvGLLCCAVAKAFGASKVIVSDIQQSRLDFAKKYIADGTFqPARVsAEENANRLKEE---HDM 269
                      67776699999****************************7644343333223444444433...344 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   4.7e-05     0.077      30      73 ..     194     238 ..     186     277 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 4.7e-05
                   SBS-GTTSEEEEES-SHHHHHHHHHHHHTT-.EEEEESSSHHHHH CS
  2-Hacid_dh_C  30 lgkelsgktvGiiGlGrIGqavakrlkafgm.kviaydrskkkee 73 
                   +g+ + g+ v ++G+G +G     ++kafg+ kvi+ d ++++ +
    EEA18830.1 194 QGNIVPGSSVVVFGAGPVGLLCCAVAKAFGAsKVIVSDIQQSRLD 238
                   67778899***********************99999999987554 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.1   6.9e-05      0.11       2      32 ..     202     233 ..     201     247 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 6.9e-05
                  SEEEE--SHHHHHHHHHH.HHTT--EEEE-SS CS
  HI0933_like   2 dviviGgGaAGlmaAisa.akrgkrVllleka 32 
                  +v+v G+G+ Gl++++ a a   ++V++ + +
   EEA18830.1 202 SVVVFGAGPVGLLCCAVAkAFGASKVIVSDIQ 233
                  69************999944555677777755 PP

>> AdoHcyase_NAD  S-adenosyl-L-homocysteine hydrolase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.5    0.0002      0.33      20      54 ..     197     232 ..     187     237 .. 0.87
   2 ?   -3.6   0.0       6.1   9.9e+03      75      92 ..     269     286 ..     260     313 .. 0.59

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.0002
                    --TTSEEEEE--SHHHHHHHHHHHHCT-.EEEEE-S CS
  AdoHcyase_NAD  20 llaGkvavvaGyGdvGkGcaaslkglGa.rvivtev 54 
                    ++ G  +vv G G vG  c+a  k++Ga +viv+++
     EEA18830.1 197 IVPGSSVVVFGAGPVGLLCCAVAKAFGAsKVIVSDI 232
                    578999*********************846888887 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 6.1
                    CTTT-SEEEE-SSSSSSB CS
  AdoHcyase_NAD  75 vvkkadivvtttGnkdii 92 
                    +++ ad+v+ ++G++  i
     EEA18830.1 269 MLAGADVVLEASGAEPAI 286
                    455556666666655444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (381 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       459  (0.025601); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.41
# Mc/sec: 2764.67
//
Query:       EEA18831.1  [L=603]
Description: D-lactate dehydrogenase (cytochrome) [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.5e-61  208.2   0.0    2.1e-61  207.7   0.0    1.2  1  FAD-oxidase_C  FAD linked oxidases, C-terminal domain
    1.9e-37  128.1   0.0    3.2e-37  127.3   0.0    1.4  1  FAD_binding_4  FAD binding domain


Domain annotation for each model (and alignments):
>> FAD-oxidase_C  FAD linked oxidases, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  207.7   0.0   2.4e-65   2.1e-61       1     249 [.     347     588 ..     347     589 .. 0.98

  Alignments for each domain:
  == domain 1  score: 207.7 bits;  conditional E-value: 2.4e-65
                    --SEEEEEEEEESSHHHHHHHHHHHHHHT---SEEEEE-HHHHHHHHHTS-SSTTS-TTT-EEEEEEEEE-HHHHHHHHHHHHHHHTTT-EEEEE. CS
  FAD-oxidase_C   1 lpearavalvafpsfeaavkavreiaqagiipaalelmdkkaldlveatkgakkglpdeeealllvefegddeeeaeeelealveaileatgaadv 96 
                    +p++++va+++fps+++a++++r+++++gi++a le++d++++++++a k +  + ++ e+++l+++f+g+    ++e++   v+++++ tg++++
     EEA18831.1 347 KPKSESVAVASFPSVQDAADCARRVVEEGIQVAGLEILDDVQMQCINASKTT--RREWTEAPTLFFKFAGTP-SGVKEQIG-IVQKLAKVTGGKTF 438
                    699*************************************************..******************.89999999.9************* PP

                    .........ETGGGGGGGGHHHHHHHHHCTTEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHEEEEEEEEEETTEEEEEEEEEEE..--TT--THHH CS
  FAD-oxidase_C  97 lvaqdeaeaealwkaRkaalpylrdallkagvavlseDtsvPvsrladlvrdikalldkyglevvlfgHagdgnlhlyilfdladeaeeeraeklv 192
                     +a+d+ae+++lw aRkaal+ l  ++++++  v+++D++vP+srl+d+v+++k+ l ++gl + ++gH+gdgn+h  ilf   +++++  ae++v
     EEA18831.1 439 EFARDDAEMKELWSARKAALWSLMAMKKDPSDHVWTTDVAVPISRLPDIVERTKKDLTQSGLLAGICGHVGDGNFHAIILF---NDKQKPLAEEVV 531
                    *********************************************************************************...669999****** PP

                    HHHHHHHHHTT-----------------------THHHHHHHHHHHH-TT--BSTT- CS
  FAD-oxidase_C 193 devvdlavelgGsisgEHGvGldkkaylerekgeeglalmrriKaalDPkgiLNPgk 249
                    +++v  ave+ G+++gEHGvGl k++yl+ e ge ++++mr++K alDP  +LN  k
     EEA18831.1 532 HRMVVNAVEMEGTVTGEHGVGLIKRDYLPHELGEPTVDVMRKLKFALDPLCLLNCDK 588
                    ***************************************************999665 PP

>> FAD_binding_4  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.3   0.0   3.6e-41   3.2e-37       3     138 ..     176     310 ..     174     311 .. 0.97

  Alignments for each domain:
  == domain 1  score: 127.3 bits;  conditional E-value: 3.6e-41
                    EEEEESSHHHHHHHHHHHHHCTSCEEEESSSTTEESTTC.SCCEEEEEETTS--EEEEETTTTEEEEETTSBHHHHHHHHHHHTTECSSGGGTTCG CS
  FAD_binding_4   3 avvrpeseeevaaalrlaneaglpvlvrGgGssllgqav.atggvvldlsrlnrileideeegtatveaGvtlgdlvealaakglllglepgsgip 97 
                    +vv+pe++eev++++++++e+ +pv++++gG+sl g+   ++ggv +d++r+++il + +e+  ++v++ v +++l+e++a++gl+++++pg g  
     EEA18831.1 176 IVVYPETTEEVSRIMKVCHERVIPVTPYSGGTSLEGHYApTRGGVCVDFRRMDKILAFHKEDLDVVVQPAVGWEELNEEIAKEGLFFPPDPGPG-- 269
                    69*********************************998889********99*************************************999988.. PP

                    SBHHHTTTTT-EETTEEGG--HHGTEEEEEEEETTSEEEEE CS
  FAD_binding_4  98 gtvGGaiatnagGygsekyGlirdnvlglevvladGevvrl 138
                    +++GG++ t+ +G+++ +yG++r++v++l+vvladG+v+++
     EEA18831.1 270 AMIGGMVGTGCSGTNAYRYGTMREWVVSLTVVLADGTVIKT 310
                    78************************************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (603 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       539  (0.030063); expected 358.6 (0.02)
Passed bias filter:                      465  (0.0259356); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.26s 00:00:00.81 Elapsed: 00:00:00.40
# Mc/sec: 4540.83
//
Query:       EEA18832.1  [L=397]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1733  (0.096659); expected 358.6 (0.02)
Passed bias filter:                      632  (0.0352502); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.61u 0.33s 00:00:00.94 Elapsed: 00:00:00.48
# Mc/sec: 2477.84
//
Query:       EEA18833.1  [L=597]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.7e-19   68.4   0.8      2e-18   66.3   0.8    2.2  1  Clr5             Clr5 domain
  ------ inclusion threshold ------
      0.075   12.0   1.4       0.18   10.8   0.7    1.8  2  Arabino_trans_C  EmbC C-terminal domain


Domain annotation for each model (and alignments):
>> Clr5  Clr5 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.3   0.8   2.2e-22     2e-18       2      53 ..       2      53 ..       1      54 [. 0.97

  Alignments for each domain:
  == domain 1  score: 66.3 bits;  conditional E-value: 2.2e-22
        Clr5  2 eedWeahkatIrrLYleenrsLkdvmeiMeeehgFkatkrqyktrfkkWgfr 53
                 ++We ++++++++Y+  ++ L+++me+M+++++F+++kr+++t+fk+Wgf+
  EEA18833.1  2 VYEWEGKRELCYQMYIVDKKGLDEIMEYMKNTYQFSPSKRAFQTQFKRWGFP 53
                59*************************************************8 PP

>> Arabino_trans_C  EmbC C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.7     2e-05      0.18      11      68 ..     438     495 ..     432     505 .. 0.92
   2 ?   -1.4   0.0       0.1   9.3e+02     302     327 ..     510     535 ..     503     545 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 2e-05
                      XXXXX-HHHHHHHHHHHSTTGGGGTEEEES-GGGGB--BS.SS-HHHHTTSSEEES-B CS
  Arabino_trans_C  11 qypaysvaksNlealagnscglAddvlvEedpnaglLtpleeadaaeaLageestgFt 68 
                       ++ay+ + sNl++ a  s ++A++ l E + + +lL++++++++a+aL++++  +F+
       EEA18833.1 438 TSNAYTHGISNLASEALASASMASNDLGEMQIDPSLLQAANDTSLAQALQQNSDPAFN 495
                      578***********************************************99888885 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.1
                      EEEE---------------------- CS
  Arabino_trans_C 302 yrilpdrkgakasstwqdaegGGplg 327
                      +ri+p+ + ++as+tw  + +   l 
       EEA18833.1 510 FRISPQSQSHTASRTWIGKISSTSLV 535
                      7***************9887665555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (597 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       992  (0.0553294); expected 358.6 (0.02)
Passed bias filter:                      557  (0.031067); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.30s 00:00:00.93 Elapsed: 00:00:00.48
# Mc/sec: 3733.59
//
Query:       EEA18834.1  [L=74]
Description: DNA-directed RNA polymerases N/8 kDa subunit superfamily [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.9e-31  107.1   1.3    4.7e-31  106.9   1.3    1.1  1  RNA_pol_N  RNA polymerases N / 8 kDa subunit


Domain annotation for each model (and alignments):
>> RNA_pol_N  RNA polymerases N / 8 kDa subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.9   1.3   2.6e-35   4.7e-31       1      59 []       1      59 [.       1      59 [. 0.99

  Alignments for each domain:
  == domain 1  score: 106.9 bits;  conditional E-value: 2.6e-35
                ----SS-TTT--B-STHHHHHHHHHHTT--HHHHHHHHT--SHHHHHHHHTB--THHHH CS
   RNA_pol_N  1 MiiPVrCFtCGkvigekweeylellekgeepkdaLdaLglkryCCrrmllthvdliekl 59
                MiiPVrCF+CGkv+g++we+yl+ll++g  ++da+d+Lg+kryCCrrm++thvdliekl
  EEA18834.1  1 MIIPVRCFSCGKVVGDLWERYLQLLDEGVPDGDAMDQLGCKRYCCRRMVMTHVDLIEKL 59
                9********************************************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (74 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       626  (0.0349155); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.35u 0.27s 00:00:00.62 Elapsed: 00:00:00.40
# Mc/sec: 558.49
//
Query:       EEA18835.1  [L=885]
Description: WD repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.5e-05   25.6   4.5       0.14   13.1   0.1    5.9  6  WD40         WD domain, G-beta repeat
    0.00014   22.1   0.4        1.1    9.6   0.0    4.5  3  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
  ------ inclusion threshold ------
      0.093   12.8   0.1       0.28   11.3   0.0    1.7  2  DUF2396      Protein of unknown function (DUF2396)


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.12   7.1e+02       3      38 .]      97     135 ..      95     135 .. 0.61
   2 ?   -1.3   0.0       0.8   4.8e+03      13      29 ..     207     223 ..     199     228 .. 0.80
   3 ?   -3.5   0.0         3   1.8e+04      10      17 ..     256     261 ..     253     276 .. 0.80
   4 !   13.1   0.1   2.3e-05      0.14       7      37 ..     313     344 ..     308     345 .. 0.83
   5 ?    2.0   0.0     0.075   4.5e+02      23      37 ..     578     591 ..     554     592 .. 0.72
   6 ?    4.7   0.1     0.011        63       6      35 ..     623     652 ..     614     655 .. 0.78

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.12
                 EEEEEE....SSSSEEEEE.EETTSSEEE.EEETTSEEEEEE CS
        WD40   3 clrtlt....GHssvtsla.fspdgawla.sGsdDgtvriWd 38 
                 +++tlt     H  vt+l+ +++d + l  s +  g +  Wd
  EEA18835.1  97 PVKTLTmkdsSH--VTGLQlVPSDPQHLYiSTH-SGRLIQWD 135
                 566665333355..****984444444541456.99999998 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.8
                 EEEEEEETTSSEEEEEE CS
        WD40  13 vtslafspdgawlasGs 29 
                 +t+l++ + g++++++ 
  EEA18835.1 207 ITHLKVVQGGQFIVACA 223
                 799999999***99986 PP

  == domain 3  score: -3.5 bits;  conditional E-value: 3
                 SSSEEEEE CS
        WD40  10 Hssvtsla 17 
                 H  +t+l+
  EEA18835.1 256 H--ITCLD 261
                 4..99995 PP

  == domain 4  score: 13.1 bits;  conditional E-value: 2.3e-05
                 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 
                 l  H   v sl++s+dg++++sG++   + +W
  EEA18835.1 313 LHWHrEAVASLRWSRDGNYISSGGKESVLVFW 344
                 556877799***************88888888 PP

  == domain 5  score: 2.0 bits;  conditional E-value: 0.075
                 SEEEEEETTSEEEEE CS
        WD40  23 awlasGsdDgtvriW 37 
                  +++ Gs D t+++W
  EEA18835.1 578 EFVTLGS-DLTIKVW 591
                 4443399.******* PP

  == domain 6  score: 4.7 bits;  conditional E-value: 0.011
                 EEESSSSEE..EEEEETTSSEEEEEETTSEEE CS
        WD40   6 tltGHssvt..slafspdgawlasGsdDgtvr 35 
                 ++ GH ++t  +++fs dg+ la G  ++ v+
  EEA18835.1 623 SYAGH-DITtgAMSFSEDGSILAVGL-KNAVH 652
                 577**.99657999********9886.66665 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0       0.2   1.2e+03      54      86 ..      80     111 ..      71     137 .. 0.60
   2 !    4.6   0.0    0.0069        41      39      70 ..     318     349 ..     309     404 .. 0.75
   3 !    9.6   0.0   0.00018       1.1      36      90 ..     626     679 ..     599     681 .. 0.78

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.2
  ANAPC4_WD40  54 avaysdgevrlldaesgkvvhslsvksekavtc 86 
                    +  d +v++++  +++ v++l++k++++vt 
   EEA18835.1  80 FLSRGD-AVQVYSLATQRPVKTLTMKDSSHVTG 111
                  433333.45556666666666665555555544 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.0069
  ANAPC4_WD40  39 sevrsLaWkpdgklLavaysdgevrlldaesg 70 
                  + v sL+W+ dg+ +  + +++ + + +  sg
   EEA18835.1 318 EAVASLRWSRDGNYISSGGKESVLVFWQLDSG 349
                  56788888888888887777766665555554 PP

  == domain 3  score: 9.6 bits;  conditional E-value: 0.00018
  ANAPC4_WD40  36 kedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgWg 90 
                  ++d +  ++++++dg++Lav+ + ++v+l+d  +  v  s +v s +++ +++++
   EEA18835.1 626 GHDITTGAMSFSEDGSILAVGLK-NAVHLIDTRQWSVYCSRQVFSADSIRSVEFQ 679
                  444444589************97.68******99999999999888888888775 PP

>> DUF2396  Protein of unknown function (DUF2396)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   4.7e-05      0.28      44     128 ..     175     257 ..     165     280 .. 0.87
   2 ?   -2.8   0.0         1   6.1e+03      42      61 ..     650     666 ..     647     676 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 4.7e-05
     DUF2396  44 hlqsgrkwrlwegkwyrqhthpdgirfeihealdrlytqGyratkviiaeryrelvssylerksskreksesakprlyGlPvefs 128
                 + +  r+    + +w +++  p+++ f+  +++ +l    ++  + i+a   ++l+  +l  ks+++ + +  + r y lPv+  
  EEA18835.1 175 KTKGARCHIAVNTDWTQRKDAPETVVFDTANVITHLKV--VQGGQFIVACARQQLIIGTLSPKSKETGTFDDYEWREYRLPVKHI 257
                 566789999999**********************9965..677899*******************99999999*********865 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1
     DUF2396  42 lvhlqsgrkwrlwegkwyrq 61 
                  vhl   r+w ++     rq
  EEA18835.1 650 AVHLIDTRQWSVYCS---RQ 666
                 699999999988743...44 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (885 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       344  (0.0191868); expected 358.6 (0.02)
Passed bias filter:                      279  (0.0155614); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.66u 0.25s 00:00:00.91 Elapsed: 00:00:00.44
# Mc/sec: 5981.61
//
Query:       EEA18836.1  [L=739]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-07   30.1   0.0    6.3e-07   29.3   0.0    1.3  1  PP2C      Protein phosphatase 2C


Domain annotation for each model (and alignments):
>> PP2C  Protein phosphatase 2C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.3   0.0   3.5e-11   6.3e-07     114     179 ..     658     728 ..     649     734 .. 0.90

  Alignments for each domain:
  == domain 1  score: 29.3 bits;  conditional E-value: 3.5e-11
                 EEEEEESS-EEEEEETTEEE....EECS---STTSHHHHHHHHHTT--EEE..CCEEETTTBSBSB-EE-GG CS
        PP2C 114 lyvAnvGDSravLcrkgnak....keltedHkpsdedEreRIeeaggsvsn..gegrvngsLavsRalGDle 179
                 l+vA +GDSravL+  +  +       ++d+ + + +E++RI ++++  +   ++ rv+g  + sRa+GD +
  EEA18836.1 658 LQVACTGDSRAVLGPERAWRyigaIPWSVDQNGPKNEEIARIYKEHPDKEYvvKNRRVLGI-EASRAFGDGQ 728
                 99************99987778888**********************9888899******9.********76 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (739 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       499  (0.027832); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.45
# Mc/sec: 4882.49
//
Query:       EEA18837.1  [L=541]
Description: hexose carrier protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.2e-101  340.0  26.9   2.5e-101  339.8  26.9    1.0  1  Sugar_tr  Sugar (and other) transporter
    3.7e-23   82.0  33.5    4.4e-13   48.9  12.3    2.2  2  MFS_1     Major Facilitator Superfamily
    0.00078   18.1   4.2    0.00078   18.1   4.2    3.1  3  MFS_2     MFS/sugar transport protein
  ------ inclusion threshold ------
          3    6.0  13.6      0.064   11.5   0.9    2.9  2  OATP      Organic Anion Transporter Polypeptide (OATP) family


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  339.8  26.9  5.6e-105  2.5e-101       3     452 .]      20     470 ..      18     470 .. 0.92

  Alignments for each domain:
  == domain 1  score: 339.8 bits;  conditional E-value: 5.6e-105
                 HHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTT.S CS
    Sugar_tr   3 lvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgk.n 100
                 ++a+lg llfgYd gv++++++   f + f ++  +s+       +g +++i+ +G+++G++f+ ++gd++GR+ s + +a++++ g ++q++a  +  
  EEA18837.1  20 TIATLGFLLFGYDQGVMSGIISAKPFNTVFPATDGNSTM------QGTVTAIYEIGCLLGAMFILWFGDWLGRRRSVMLGATIMILGVIIQVTAYYDyA 112
                 7899999******************99999999999855......49***********************************************96579 PP

                 S-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHH CS
    Sugar_tr 101 svevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPrylv 199
                  + ++ivgRv++G+g G+ + ++P+y++E + ++ Rg l+ +    i+fG l+a+++++g ++  ++ +wr+++++q+v+ l +++++ flPESPr+l+
  EEA18837.1 113 PLAQFIVGRVVTGVGNGINTSTIPTYQAECSRTTNRGLLICIEGGVIAFGTLIAYWIDFGASYGPDDLTWRFPIAFQIVFGLGIIAGMAFLPESPRWLF 211
                 99************************************************************************************************* PP

                 HTT-HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH..........HTTHHHHSH.....HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH.. CS
    Sugar_tr 200 ekgkeeeakevlaklrgeedadrelaeekdsleaeqeee.....kaswkellsskt..vrqrlligvvlqifqqltGinaimyysptifenlglsks.. 289
                 ++++++e ++v+a l++ee ++  ++  k+    + +++     ++ ++ +++  +  +++r+l+g+  q++qq  G+na++yy p +fe+   ++   
  EEA18837.1 212 MRERYQEGEAVIAALMNEEINSHGVQLQKTLVLDSIRASgqmgqSTPLRAVFTGGKtqHLRRMLLGASSQLMQQIGGCNAVIYYFPILFETSIGQTHtl 310
                 *****************977777766666665555555555557778888887654699*******************************877777757 PP

                 .HHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHH CS
    Sugar_tr 290 .llvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRska 387
                  ll  ++ ++v  ++  +++fl++r+GRR+l+l G++g+++ +v+    a+l++ +  +a+ +a v+++ +ia f+++w p+pw++ +E++p ++R+ka
  EEA18837.1 311 sLLLGGVNMIVYSIFATMSWFLIERVGRRKLFLYGTVGQCLSMVLTF--ACLIPGTP-SAAKGAAVGLFTYIASFGATWLPLPWLYPAEISPIKTRAKA 406
                 7778888888888899999*************************998..55555553.5799************************************* PP

                 HHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 388 laiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                  a+++++nwl+nfli +++p++ ++ig ++++l+fa++++ f+ +++f +pet+ r+leei+ +f
  EEA18837.1 407 NALSTCTNWLFNFLIVMVTPVMISNIG-WGTYLFFAIVNACFLPIIYFWYPETARRSLEEIDLIF 470
                 ***************************.*********************************9776 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.9  12.3   9.7e-17   4.4e-13      20     177 ..      44     208 ..      15     245 .. 0.79
   2 !   39.2  13.1   8.9e-14     4e-10      13     181 ..     290     464 ..     274     500 .. 0.78

  Alignments for each domain:
  == domain 1  score: 48.9 bits;  conditional E-value: 9.7e-17
       MFS_1  20 pl.alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.....sslwlllvlrvlqGlgagalfpagaaliad 112
                 p  ++  +   + + +g+++++y +g++++++++ +++d +Grrr ++lg+++++lg +++ ++     ++l  ++v+rv++G+g g+ ++++ ++ a+
  EEA18837.1  44 PFnTVFPATDGNSTMQGTVTAIYEIGCLLGAMFILWFGDWLGRRRSVMLGATIMILG-VIIQVTayydyAPLAQFIVGRVVTGVGNGINTSTIPTYQAE 141
                 333333333378999******************************************.7777423666677778************************* PP

       MFS_1 113 wfpkeergraigllsagfslGailgpllggllasslg.....Wrav..fyilaivsllafvlfllllpeepp 177
                  +  ++rg+ i + ++ +++G+++++ +    +  +g     Wr +  f i+ +++++a++   ++lpe+p+
  EEA18837.1 142 CSRTTNRGLLICIEGGVIAFGTLIAYWIDFGAS--YGpddltWRFPiaFQIVFGLGIIAGM---AFLPESPR 208
                 ************************999865444..55678887776115555555555555...78877764 PP

  == domain 2  score: 39.2 bits;  conditional E-value: 8.9e-14
       MFS_1  13 silgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.......sslw.lllvlrvlqGlgagalf 103
                 ++++  +p++  ++ g +++   ll ++ ++++++++    +l++r+Grr+++l g ++ +l+ ++l+fa       s    + + l    + ++++ +
  EEA18837.1 290 NAVIYYFPILFETSIGQTHTLSLLLGGVNMIVYSIFATMSWFLIERVGRRKLFLYGTVGQCLS-MVLTFAclipgtpSAAKgAAVGLFTYIASFGATWL 387
                 4566667766666677455554457777***********************************.66666445655532233334444444444558999 PP

       MFS_1 104 pagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkr 181
                 p+   + a+++p + r++a++l + ++ l   l  ++ ++++s++gW ++++++aiv + ++ ++++++pe+++++  
  EEA18837.1 388 PLPWLYPAEISPIKTRAKANALSTCTNWLFNFLIVMVTPVMISNIGW-GTYLFFAIVNACFLPIIYFWYPETARRSLE 464
                 ***********************************************.9************77766777666655543 PP

>> MFS_2  MFS/sugar transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   4.2   1.7e-07   0.00078     257     338 ..      55     134 ..      45     169 .. 0.79
   2 !   12.4   6.0   9.4e-06     0.042     223     330 ..     268     384 ..     243     398 .. 0.73
   3 ?   -1.3   0.6      0.13     6e+02     259     309 ..     404     455 ..     398     463 .. 0.64

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 1.7e-07
       MFS_2 257 ngsaasvfllvvtisallgiplwqplakrlgkkntyllgalltivllvlvlll..qpsnlllflvllviagfgvgvaallpwsm 338
                 n ++  +++++  i+ llg++++ ++  +lg++++++lga+++i++ ++ + +  + + l+ f+v  v++g+g g+     +s+
  EEA18837.1  55 NSTMQGTVTAIYEIGCLLGAMFILWFGDWLGRRRSVMLGATIMILGVIIQVTAyyDYAPLAQFIVGRVVTGVGNGI----NTST 134
                 55566677777789999************************************66666666667777777766444....4444 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 9.4e-06
       MFS_2 223 nraflillllfllaalalgvlnglllYyl....tyvlg.ngsaasvfllvvtisallgiplwqplakrlgkkntyllgalltivllvlvlll......q 310
                  + ++++ll+++ +++ +  ++++++Yy+    +  +g + +   ++ +v +i   +++ + + l  r g+++++l g++ + + +vl+++       +
  EEA18837.1 268 TQHLRRMLLGASSQLMQQIGGCNAVIYYFpilfETSIGqTHTLSLLLGGVNMIVYSIFATMSWFLIERVGRRKLFLYGTVGQCLSMVLTFAClipgtpS 366
                 56789999********************8222245566333333333344477777************************9999999999997777554 PP

       MFS_2 311 psnlllflvllviagfgvgv 330
                 +++ +++ +++ ia+fg  +
  EEA18837.1 367 AAKGAAVGLFTYIASFG--A 384
                 44444444555555544..2 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.13
       MFS_2 259 saasvfllvv.tisallgiplwqplakrlgkkntyllgalltivllvlvlll 309
                 ++a+++++++  + ++l +++ +++ + +g  ++ +++++ + +l ++ ++ 
  EEA18837.1 404 AKANALSTCTnWLFNFLIVMVTPVMISNIGWGTYLFFAIVNACFLPIIYFWY 455
                 5556666666566667777777777777777666666666666666666655 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.9   1.4e-05     0.064      35      86 ..      56     107 ..      53     115 .. 0.87
   2 ?   -2.4   5.6      0.24   1.1e+03     135     382 ..     117     358 ..     110     373 .. 0.51

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 1.4e-05
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP  35 sstsgliassneignillilfvsYfggrghrPrwigigallmalgslllalP 86 
                 s+  g +++++eig++l ++f+ +fg+   r r + +ga +m lg ++ +  
  EEA18837.1  56 STMQGTVTAIYEIGCLLGAMFILWFGDWLGRRRSVMLGATIMILGVIIQVTA 107
                 77889***********************999999999999999999887655 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.24
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xx..xxxxxxxxxxxxxx RF
        OATP 135 fflaqlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllklyvdidseisltpkdprWvg..aW..Wlgflilgvlllla 229
                 f+++ ++ G+G+    +   +Y  + ++++n  l++ i   + ++G  +++         ++d+  + s  p+d  W    a+    g  i++ +++l 
  EEA18837.1 117 FIVGRVVTGVGNGINTSTIPTYQAECSRTTNRGLLICIEGGVIAFGTLIAY---------WIDF--GASYGPDDLTWRFpiAFqiVFGLGIIAGMAFLP 204
                 666777777777777777777777777777777777776666666666665.........3444..333334444443211331123444555555555 PP

                 xxxxxxxxxx..xxxxxxxxxxxxxxxxxx..x.....xxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 230 aiplffFPke..lpkkkeerakkkseeesa..e.....kkeekkkkekskssee....eelkslkdfpkalkrllknpifllvilssvfeillvaGfit 315
                   p ++F +e  +++++  +a  ++e +s+  +            ++            + ++l+ +++  k     +++l  + + + +i + +++i 
  EEA18837.1 205 ESPRWLFMREryQEGEAVIAALMNEEINSHgvQlqktlV-----LDSIR----AsgqmGQSTPLRAVFTGGKTQHLRRMLLGASSQLMQQIGGCNAVIY 294
                 555555555533333333333333333222221111111.....11111....0111133344444444445555555555555555666667777777 PP

                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 316 FlpkylEtqFslsaseAnlltGvvvipgaalGillgGllvkklklsakklaklvlvvsllsllllll 382
                 + p   Et  +++ + + ll Gv +i+ +++ + ++ +l++++    +kl  + +v ++ls++l+++
  EEA18837.1 295 YFPILFETSIGQTHTLSLLLGGVNMIVYSIFAT-MSWFLIERV--GRRKLFLYGTVGQCLSMVLTFA 358
                 777777777777777777666666666666554.455666654..4455555555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (541 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       523  (0.0291706); expected 358.6 (0.02)
Passed bias filter:                      260  (0.0145016); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 3486.82
//
Query:       EEA18838.1  [L=115]
Description: hypothetical protein PMAA_011160 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (115 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       311  (0.0173462); expected 358.6 (0.02)
Passed bias filter:                      252  (0.0140554); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.44
# Mc/sec: 783.24
//
Query:       EEA18839.1  [L=451]
Description: hypothetical protein PMAA_011210 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (451 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       242  (0.0134977); expected 358.6 (0.02)
Passed bias filter:                      235  (0.0131073); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 2935.99
//
Query:       EEA18840.1  [L=130]
Description: hypothetical protein PMAA_011220 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (130 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       582  (0.0324614); expected 358.6 (0.02)
Passed bias filter:                      488  (0.0272185); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.48
# Mc/sec: 818.75
//
Query:       EEA18841.1  [L=243]
Description: hypothetical protein PMAA_011230 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (243 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       470  (0.0262145); expected 358.6 (0.02)
Passed bias filter:                      388  (0.0216409); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 1731.82
//
Query:       EEA18842.1  [L=518]
Description: pogo transposable element, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.7e-31  108.1   0.0    7.4e-31  107.1   0.0    1.5  1  DDE_1      DDE superfamily endonuclease
    8.4e-06   25.4   0.0    1.8e-05   24.4   0.0    1.5  1  HTH_psq    helix-turn-helix, Psq domain
  ------ inclusion threshold ------
       0.14   11.4   1.3        9.6    5.3   0.3    2.2  2  UPF0052    Uncharacterised protein family UPF0052
       0.17   11.8   2.7        0.3   11.0   2.7    1.4  1  zf-CCHC_2  Zinc knuckle
       0.68   10.2   5.2        3.3    8.0   0.1    2.5  2  Mrpl_C     54S ribosomal protein L8 C-terminal domain
        9.9    6.6  10.2        2.7    8.4   6.4    1.9  2  CENP-H     Centromere protein H (CENP-H)


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  107.1   0.0   2.5e-34   7.4e-31       2     175 .]     165     334 ..     164     334 .. 0.95

  Alignments for each domain:
  == domain 1  score: 107.1 bits;  conditional E-value: 2.5e-34
       DDE_1   2 erltvllcanaagsekLkplvigkaksp.rafkngektkkkldveyksnrkawltssifeeWL.kvfdkrle..aekrkilLlldssrshetvel.les 95 
                 ++++++++a  +++  +++++i+kak+  r  ++   ++ ++d+++++++++w+t++i+ eWL  +f++ ++  + +++ +L+ld+++sh t+e+ +  
  EEA18842.1 165 REWVTAIEATNSTGWAIPSYIIFKAKKNgRLGWF---DDLPSDWRINISENGWTTDQIGLEWLkTHFIPYINgrSMGSYRMLILDGHGSHLTAEFdHTY 260
                 7899********************9865256666...99*********************************99*********************999* PP

       DDE_1  96 elqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                  ++ni  +++P++s++llqPld+g+++ lK++Y +++ q +  + n+++k       ld+l    +A++ a + +ti+++f
  EEA18842.1 261 TENNIIPICMPPHSSHLLQPLDVGCFAVLKRYYGQAVEQRMRLGFNHIDK-------LDFLTAFPQARTvAYKAQTIRNSF 334
                 **************************************************.......999999999999999999999887 PP

>> HTH_psq  helix-turn-helix, Psq domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4   0.0   6.1e-09   1.8e-05       2      39 ..      16      54 ..      15      58 .. 0.88

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 6.1e-09
     HTH_psq  2 pealaaAleavvnGk.mSirkAArkYgiPrsTLwrrkrg 39
                + ++++A+ +  nG   Sir+AAr+Y +Pr+TL+ r +g
  EEA18842.1 16 EGKIELAISDLKNGRiRSIREAARIYTVPRTTLQDRMNG 54
                678899999999***99*****************77655 PP

>> UPF0052  Uncharacterised protein family UPF0052
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.0    0.0047        14     206     272 ..      35     101 ..      21     117 .. 0.86
   2 ?    5.3   0.3    0.0032       9.6      97     185 ..     403     483 ..     363     485 .. 0.76

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0047
                 -SSEEEEE--SB--TTTSTT-BHHHHHHHHHHCH-SS....S-SEEE.EE-S---HHHHHHHHTTT-- CS
     UPF0052 206 skakkvlvsnimtqkGetdgfsvsdhvkaieravgkgvakayvdavl.vntsevpeellekyaaegke 272
                 ++a +++ ++ +t +  ++g++ ++  +a ++++++ + +++v  vl ++++ ++++  +ky+ e+++
  EEA18842.1  35 REAARIYTVPRTTLQDRMNGMQYRQITRANHHKLTQSEEDSLVKWVLdLDKQ-IDSKFARKYNYERAK 101
                 67999********99999*****************99888889888877666.********9997765 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0032
                 HS-HHHHHHHHHHHTT-.SSEEEES-SS--EEEEEETTS-EEESTTTGGGG-S...-EEEEEEESTT----HHHHHHHHH-SEEEE-SS- CS
     UPF0052  97 tgsleeaiealskilkv.rgrvlPatddpvelsaeledGeeitgeskisearklkapikrvflepegaeaapevleaikeAdlivlgpGs 185
                 ++++++ai  lsk+ ++  ++vl + +++++l+a  e+ ++ +++sk    +       ++  + + +ea+  v ++i++++++  +pG 
  EEA18842.1 403 NQEINQAIIRLSKAYETiANDVLLVRKENHDLRAAHEKEKQKRQKSKK---Q------ISIEHGITSEEAPALVQDQIEASQVVTTAPGK 483
                 357888888899998887889999999999999998666633333322...2......234455566678899999**********9996 PP

>> zf-CCHC_2  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   2.7   9.9e-05       0.3       5      20 ..     498     513 ..     494     514 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 9.9e-05
   zf-CCHC_2   5 vChiCgkkGHyIqdCP 20 
                  C  C++ GH I++CP
  EEA18842.1 498 RCSGCHVMGHRINQCP 513
                 6888************ PP

>> Mrpl_C  54S ribosomal protein L8 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   0.1    0.0011       3.3      21      74 ..      44      96 ..      37     121 .. 0.78
   2 ?    3.3   1.4     0.033        98      47      92 ..     413     455 ..     378     472 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0011
      Mrpl_C 21 vkttladeskakayaplTlqnLkKmlkfkskeqllkeilavrkflkeeqelewd 74
                 +ttl+d  ++ +y ++T  n +K+++   ++ l k +l + k +  +   +++
  EEA18842.1 44 PRTTLQDRMNGMQYRQITRANHHKLTQSE-EDSLVKWVLDLDKQIDSKFARKYN 96
                589*********************99864.566777777777777666655555 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.033
      Mrpl_C  47 kfkskeqllkeilavrkflkeeqelewdeeeekeavkalldqvakk 92 
                   k+ e +++++l vrk   e+++l+  +e+ek+  ++ ++q+  +
  EEA18842.1 413 LSKAYETIANDVLLVRK---ENHDLRAAHEKEKQKRQKSKKQISIE 455
                 56788999********6...99999999999999999999999333 PP

>> CENP-H  Centromere protein H (CENP-H)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.1       1.2   3.5e+03      17      37 ..      56      76 ..      46     101 .. 0.77
   2 ?    8.4   6.4   0.00092       2.7       5      90 ..     379     460 ..     376     462 .. 0.79

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 1.2
      CENP-H 17 klsqelrelqeeltevekenl 37
                +  q +r+ + +lt+ e+++l
  EEA18842.1 56 QYRQITRANHHKLTQSEEDSL 76
                556666777777777776665 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.00092
      CENP-H   5 ieqrdelssellklsqelrelqeeltevekenlrlkrknrelaaellelakekesekeklkeelekleaelkksrqrwrvvknvas 90 
                 i+q  + s+++ k  +e++  +++ +e+++ ++rl+++ +++a+++l  +ke++  +    ++ ek +++ +ks++++ +  +++s
  EEA18842.1 379 IRQFVRQSTTINKRINECTGSLNQNQEINQAIIRLSKAYETIANDVLLVRKENHDLR----AAHEKEKQKRQKSKKQISIEHGITS 460
                 78888999**************************************65555554444....5566677777777777777766665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (518 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1607  (0.0896313); expected 358.6 (0.02)
Passed bias filter:                      781  (0.0435607); expected 358.6 (0.02)
Passed Vit filter:                        67  (0.00373696); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.67u 0.28s 00:00:00.95 Elapsed: 00:00:00.45
# Mc/sec: 3427.14
//
Query:       EEA18843.1  [L=170]
Description: hypothetical protein PMAA_011250 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.6e-10   39.7   0.1      1e-09   38.3   0.0    1.8  2  HTH_Tnp_Tc5   Tc5 transposase DNA-binding domain
    0.00011   21.8   0.0     0.0002   21.1   0.0    1.4  1  HTH_psq       helix-turn-helix, Psq domain
  ------ inclusion threshold ------
      0.034   13.9   0.1      0.061   13.1   0.1    1.4  1  HTH_DeoR      DeoR-like helix-turn-helix domain
      0.061   13.4   0.1       0.11   12.7   0.1    1.4  1  SpoIIID       Stage III sporulation protein D
      0.084   12.3   0.0       0.16   11.4   0.0    1.4  1  HTH_Tnp_ISL3  Helix-turn-helix domain of transposase family I
      0.085   12.7   0.0       0.21   11.4   0.0    1.7  1  HTH_23        Homeodomain-like domain
       0.09   12.9   0.1       0.26   11.5   0.0    1.9  2  HTH_28        Helix-turn-helix domain
       0.12   12.1   0.0       0.35   10.6   0.0    1.8  1  Sigma70_r4_2  Sigma-70, region 4
       0.15   11.9   0.6        0.6    9.9   0.0    2.2  2  MerR          MerR family regulatory protein


Domain annotation for each model (and alignments):
>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       2.1   4.2e+03      25      34 ..      29      38 ..      27      48 .. 0.69
   2 !   38.3   0.0     5e-13     1e-09       2      63 ..      67     128 ..      66     131 .. 0.92

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 2.1
                 HHHHHHHHHH CS
  HTH_Tnp_Tc5 25 elirekAqel 34
                 ++ir++A+ +
   EEA18843.1 29 KTIRQTARLF 38
                 5788888877 PP

  == domain 2  score: 38.3 bits;  conditional E-value: 5e-13
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT.S-- CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh.glk 63 
                  p +E aL++W   l +rg p+++e+ re+ + l+ + +d+++p++k++ +W+d F++R+ +lk
   EEA18843.1  67 PTEEIALRNWTLSLERRGLPPRREMAREMVNVLLAE-RDKTKPPKKVGINWIDSFLSRNpDLK 128
                  78999***************************9966.8999*****************97776 PP

>> HTH_psq  helix-turn-helix, Psq domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.1   0.0   9.8e-08    0.0002       5      44 ..      16      56 ..      13      57 .. 0.88

  Alignments for each domain:
  == domain 1  score: 21.1 bits;  conditional E-value: 9.8e-08
     HTH_psq  5 laaAleavvnGk.mSirkAArkYgiPrsTLwrrkrgkyslk 44
                +++ ++av n+k  +ir+ Ar+++++  TL++r++g++++k
  EEA18843.1 16 ISLSIDAVKNKKtKTIRQTARLFDVSEATLRNRLKGGITSK 56
                56668999999988**********************99876 PP

>> HTH_DeoR  DeoR-like helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.1   3.1e-05     0.061       6      33 ..      20      47 ..      15      53 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 3.1e-05
    HTH_DeoR  6 lellkqqgklsveelvellgvSeaTiRR 33
                ++ +k++ + ++ + + l++vSeaT R+
  EEA18843.1 20 IDAVKNKKTKTIRQTARLFDVSEATLRN 47
                678999*********************7 PP

>> SpoIIID  Stage III sporulation protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.1   5.3e-05      0.11      17      38 ..      26      47 ..      14      60 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 5.3e-05
     SpoIIID 17 eskatvRkaakvfgvskstvhk 38
                ++ +t+R++a+ f+vs +t+ +
  EEA18843.1 26 KKTKTIRQTARLFDVSEATLRN 47
                46689*************9865 PP

>> HTH_Tnp_ISL3  Helix-turn-helix domain of transposase family ISL3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   7.9e-05      0.16      26      49 ..      27      50 ..      21      51 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 7.9e-05
  HTH_Tnp_ISL3 26 esrsvkavArqlgvSwtTVwrild 49
                  +++++++ Ar+++vS+ T++++l+
    EEA18843.1 27 KTKTIRQTARLFDVSEATLRNRLK 50
                  4579*****************986 PP

>> HTH_23  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00011      0.21      18      39 ..      29      50 ..      20      55 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00011
      HTH_23 18 lsvreIAreLgvsrrTvyrwlk 39
                +++r+ Ar+++vs+ T+++ lk
  EEA18843.1 29 KTIRQTARLFDVSEATLRNRLK 50
                79****************8765 PP

>> HTH_28  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   0.00013      0.26      12      34 ..      28      50 ..      20      64 .. 0.82
   2 ?   -3.2   0.0       4.8   9.5e+03      14      20 ..      87      93 ..      82      95 .. 0.53

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00013
      HTH_28 12 GhsvreaArelgisrrtvyrWik 34
                 +++r++Ar++ +s+ t++  +k
  EEA18843.1 28 TKTIRQTARLFDVSEATLRNRLK 50
                34*****************9887 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 4.8
      HTH_28 14 svreaAr 20
                ++re Ar
  EEA18843.1 87 PRREMAR 93
                5566665 PP

>> Sigma70_r4_2  Sigma-70, region 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00018      0.35      28      47 ..      30      49 ..      27      52 .. 0.92

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00018
                  -HHHHHHHHT--HHHHHHHH CS
  Sigma70_r4_2 28 sykEIAellgisegtVksrl 47
                  +++++A+l+++se+t ++rl
    EEA18843.1 30 TIRQTARLFDVSEATLRNRL 49
                  889***************99 PP

>> MerR  MerR family regulatory protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0    0.0003       0.6       1      17 [.      30      46 ..      30      47 .. 0.95
   2 ?   -1.1   0.1      0.87   1.7e+03      19      27 ..      80      88 ..      79      90 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.0003
                EHHHHHHHHTTTHHHHH CS
        MerR  1 tIgevAeltGvsprtLR 17
                tI++ A+l++vs  tLR
  EEA18843.1 30 TIRQTARLFDVSEATLR 46
                89*************** PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.87
                HHHTTSSTS CS
        MerR 19 YEreGLipp 27
                +Er+GL p+
  EEA18843.1 80 LERRGLPPR 88
                689999764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (170 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       358  (0.0199677); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.39u 0.25s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 1253.41
//
Query:       EEA18844.1  [L=506]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.9e-20   71.4   0.0    3.7e-19   69.0   0.0    2.1  2  DDE_1          DDE superfamily endonuclease
    6.7e-15   54.9   1.0    7.5e-14   51.5   0.0    2.8  3  HTH_Tnp_Tc5    Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
      0.025   14.7   1.3       0.21   11.7   0.6    2.5  2  Med9           RNA polymerase II transcription mediator compl
      0.059   12.9   0.0       0.19   11.3   0.0    1.9  1  HTH_24         Winged helix-turn-helix DNA-binding
       0.12   12.2   0.0       0.29   11.0   0.0    1.7  1  LexA_DNA_bind  LexA DNA binding domain


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.0   0.0     1e-22   3.7e-19       2     174 ..     203     370 ..     202     371 .. 0.88
   2 ?   -1.0   0.0      0.34   1.2e+03     119     168 ..     449     496 ..     443     501 .. 0.78

  Alignments for each domain:
  == domain 1  score: 69.0 bits;  conditional E-value: 1e-22
       DDE_1   2 erltvllcanaagsekLkplvigkaksprafkngektkkkldveyksnrkawltssifeeWLkvfdkrle..aekrkilLlldssrshetvel.lesel 97 
                 ++l+ +++ ++a+++k++p++i+ +k + ++++  k  k+ d+ +++ +k+   ++i  eWL++fdk ++  a ++  lL +d++++h t e+ + +++
  EEA18844.1 203 RELVSTIEGISATGNKIPPMLIFTGKAILESWF--KYLKEEDWLITIGDKGYSNDTIAYEWLQHFDKHTReqAGNNFRLLFMDNHDAHITSEFlSYCDK 299
                 5788999**************************..999********************************98889999***************99**** PP

       DDE_1  98 qniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksa 174
                  +i ++ +P++++++lqPld   + + K+  rr+++ ++  +    +k        d+l++i++ +  a++++ i+++
  EEA18844.1 300 YKILAIAFPPHTTHILQPLDGLPFMQYKRIHRRAINDQAHLGGYFYDK-------IDFLANIARVRAeALTPRVIRNG 370
                 ********************9999999999999888777665555555.......66666666666656666666665 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.34
       DDE_1 119 gvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwnavsk 168
                 g+   lK+ +   l qa ++ q++ +   ++l+ l+a k  kk+  +v++
  EEA18844.1 449 GIRRSLKKIFDGSLTQADIKDQQQAQI--ERLQTLNARKSAKKSKRQVQV 496
                 566778888888888888887776665..788889999999998888775 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.5   0.0   2.1e-17   7.5e-14       2      61 ..      64     123 ..      63     130 .. 0.93
   2 ?   -3.3   0.0       2.7   9.7e+03       9      25 ..     148     166 ..     146     168 .. 0.76
   3 ?    0.7   0.1      0.15   5.5e+02      28      56 ..     231     265 ..     225     269 .. 0.64

  Alignments for each domain:
  == domain 1  score: 51.5 bits;  conditional E-value: 2.1e-17
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHTS CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRhg 61 
                  +++E+a++ W+++l+ rgip++ ++i+++A++++++ + + ++ ++++ +W++rF+kR+g
   EEA18844.1  64 DDQERAIILWMNDLDDRGIPPSVRMIKNYAEKVHQNMHPNADSLPQLGDRWVYRFLKRLG 123
                  79********************************88899999****************94 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 2.7
                  HHHHHHH..C-CT---SCH CS
  HTH_Tnp_Tc5   9 leWirql..rergipitge 25 
                  + W+ +l  + +++ it +
   EEA18844.1 148 QTWFDRLeiAIQNYKITPS 166
                  5799988888888888865 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 0.15
                  HHHHHHHH......HHSSSCT-TT-S--CHHHHHH CS
  HTH_Tnp_Tc5  28 rekAqela......slaadlgepdfkaSkgWldrF 56 
                   e + +++       ++ d+g+++ +  ++Wl++F
   EEA18844.1 231 LESWFKYLkeedwlITIGDKGYSNDTIAYEWLQHF 265
                  55555555544445445777888888888899988 PP

>> Med9  RNA polymerase II transcription mediator complex subunit 9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0      0.28     1e+03      37      51 ..     201     215 ..     200     218 .. 0.87
   2 ?   11.7   0.6   5.7e-05      0.21      18      70 ..     430     486 ..     408     490 .. 0.80

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.28
        Med9  37 karelirelpgidrs 51 
                 + rel+++++gi+ +
  EEA18844.1 201 SSRELVSTIEGISAT 215
                 679*********987 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 5.7e-05
        Med9  18 nlsskdletktgelrhkLkkarelirelpgidrs....veeqeaeieeleeqlakKr 70 
                 ++s+k+++t+++e+ + +  +r  ++++ + + +    +++q+a+ie l+  +a+K 
  EEA18844.1 430 QRSIKKVDTQLNEISDAIPGIRRSLKKIFDGSLTqadiKDQQQAQIERLQTLNARKS 486
                 6999************************9966552233689999****999999886 PP

>> HTH_24  Winged helix-turn-helix DNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   5.4e-05      0.19       9      38 ..      17      46 ..      11      47 .. 0.94

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 5.4e-05
      HTH_24  9 LelLqknprisqreLAerlglSpstvnrrl 38
                Le+L+knp+  ++ LA++ g+  + ++rr+
  EEA18844.1 17 LEILRKNPKQKIKPLARQFGVDYQRLRRRV 46
                9************************99997 PP

>> LexA_DNA_bind  LexA DNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0     8e-05      0.29       2      32 ..      60      90 ..      59      94 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 8e-05
                   X---HHHHHHHHHHHHHHHHHSS---HHHHH CS
  LexA_DNA_bind  2 kkLTerQrevldlikasieetgypPsireia 32
                   k LT+ Q++ + l  + ++++g pPs+r i 
     EEA18844.1 60 KRLTDDQERAIILWMNDLDDRGIPPSVRMIK 90
                   689****9988888899***********986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (506 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       954  (0.0532099); expected 358.6 (0.02)
Passed bias filter:                      692  (0.0385967); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.68u 0.32s 00:00:01.00 Elapsed: 00:00:00.50
# Mc/sec: 3028.13
//
Query:       EEA18845.1  [L=362]
Description: RNA methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      1e-06   28.7   0.0    1.8e-06   27.8   0.0    1.5  1  Methyltransf_31  Methyltransferase domain
    4.4e-06   26.3   0.2    0.00082   19.0   0.0    2.3  2  MTS              Methyltransferase small domain
    0.00011   21.6   0.0    0.00048   19.5   0.0    1.8  1  N6_Mtase         N-6 DNA Methylase
    0.00046   19.7   0.0    0.00069   19.1   0.0    1.2  1  PrmA             Ribosomal protein L11 methyltransferase (Prm
     0.0096   16.6   0.0      0.022   15.4   0.0    1.7  1  Methyltransf_25  Methyltransferase domain
  ------ inclusion threshold ------
      0.014   14.9   0.0      0.023   14.2   0.0    1.3  1  AviRa            RRNA methyltransferase AviRa
      0.017   14.5   0.0      0.075   12.3   0.0    1.9  1  Methyltransf_10  RNA methyltransferase
      0.027   15.1   0.4       0.11   13.1   0.2    2.1  2  PrmC_N           PrmC N-terminal domain
      0.038   14.7   0.0        0.1   13.4   0.0    1.8  1  Methyltransf_12  Methyltransferase domain


Domain annotation for each model (and alignments):
>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0   9.1e-10   1.8e-06       3      48 ..     132     180 ..     130     232 .. 0.85

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 9.1e-10
  Methyltransf_31   3 kglrvlDlGCGtGeltfelaeelgpkae...vvGiDiseeaielArena 48 
                      k lr+lDl +G+G +++ l+++l ++++   +vGiD +++ai+l+++n 
       EEA18845.1 132 KSLRILDLCSGSGCISLLLHSLLASDIKdltIVGIDVDPQAIKLSQKNK 180
                      789******************8888777777***************983 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.0   0.0   4.1e-07   0.00082      32      78 ..     133     183 ..     126     207 .. 0.79
   2 !    5.3   0.1    0.0066        13      85     111 ..     219     245 ..     204     258 .. 0.75

  Alignments for each domain:
  == domain 1  score: 19.0 bits;  conditional E-value: 4.1e-07
                 CSEEEEET-TTSHHHHHH....HHHTTC.EEEEEESBHHHHHHHHHHHHHT CS
         MTS  32 sgkvlDlGcGaGvlgaal....akespeaevtlvdvdarAlesakenlean 78 
                 s ++lDl++G G +++ l    a+  ++++++ +dvd +A++++++n  +n
  EEA18845.1 133 SLRILDLCSGSGCISLLLhsllASDIKDLTIVGIDVDPQAIKLSQKNKLHN 183
                 5579***********976211156677889999*************98776 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0066
                 EE-STTTTSTTS-EEEEEE---STTTC CS
         MTS  85 vasdvleeveekkfdlivsNPPfhagk 111
                 ++s   +  +++  d+++sNPP+ + +
  EEA18845.1 219 LQSHFHASNTNNTWDVLISNPPYISPS 245
                 55666666677999********87655 PP

>> N6_Mtase  N-6 DNA Methylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0   2.4e-07   0.00048      49     138 ..     135     244 ..     125     271 .. 0.84

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 2.4e-07
    N6_Mtase  49 svyDpacGsggllvqaekvlkeedgktkelsiyGqeknettyrLakmNlllhgieykkvkirlgdtlekpkfe........................kd 123
                  ++D ++Gsg + +  ++ l   + ++k+l+i G ++++++++L++ N  lh+i    ++ r ++     kf+                        ++
  EEA18845.1 135 RILDLCSGSGCISLLLHSLL---ASDIKDLTIVGIDVDPQAIKLSQKNK-LHNIRRGLLSSRAENEVYFIKFDilhsiqsgnsslmgtlqshfhasnTN 229
                 59********9999999998...79***********************5.8******999999999888888888899999999************999 PP

    N6_Mtase 124 kkfdvvvaNppfnqk 138
                 ++ dv ++Npp+ + 
  EEA18845.1 230 NTWDVLISNPPYISP 244
                 9***********665 PP

>> PrmA  Ribosomal protein L11 methyltransferase (PrmA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   3.5e-07   0.00069     161     209 ..     132     185 ..     126     207 .. 0.73

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 3.5e-07
        PrmA 161 egeevlDvGtGSGiLaiaaakLgak.....kvvavDiDevAvkvakeNaelNkv 209
                 +  ++lD+  GSG +++  + L a+     ++v++D+D++A+k +++N   N  
  EEA18845.1 132 KSLRILDLCSGSGCISLLLHSLLASdikdlTIVGIDVDPQAIKLSQKNKLHNIR 185
                 45589********99988777766522222689***************988854 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   1.1e-05     0.022       1      41 [.     136     180 ..     136     230 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 1.1e-05
                      EEEET-TTSHHHHHHHCTS....TSSEEEEEESSHHHHHHHHHHH CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrl....gkakvtgvDiseemleaarera 41 
                      +Ldl+ G+G ++l l+  l    ++ +++g+D+++++++  +++ 
       EEA18845.1 136 ILDLCSGSGCISLLLHSLLasdiKDLTIVGIDVDPQAIKLSQKNK 180
                      8*********999999988765459**************999876 PP

>> AviRa  RRNA methyltransferase AviRa
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   1.1e-05     0.023      52     121 ..     131     202 ..     115     248 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 1.1e-05
       AviRa  52 gapltlyDpCCGgayLltvlgllhgkkik..kvlasDvdeevlelakkNLsLLtkeglakreeelrelaeey 121
                  ++l++ D C G++ +   l  l ++ ik  ++++ Dvd ++++l++kN     + gl + ++e + ++ ++
  EEA18845.1 131 RKSLRILDLCSGSGCISLLLHSLLASDIKdlTIVGIDVDPQAIKLSQKNKLHNIRRGLLSSRAENEVYFIKF 202
                 46799***************99999999934579***************65555666655555555555555 PP

>> Methyltransf_10  RNA methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   3.8e-05     0.075      83     149 ..     111     183 ..      94     271 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 3.8e-05
                      HHHHHHHHHHHTGGGSG..TTS--EEEEES-TTTTH....HHHHHHHHH--EEEEEES-HHHHHHHHHHHHHT CS
  Methyltransf_10  83 adyihyvadllgkadsd..isaqvraldiGvGanCi....yPllGvteyGWrfvgsevddvslasakaivesn 149
                        y  +  d++ k+       +++r+ld+  G+ Ci    + ll       + vg +vd+++++ ++++   n
       EEA18845.1 111 ESYTSHARDIIMKGPYAkdFRKSLRILDLCSGSGCIslllHSLLASDIKDLTIVGIDVDPQAIKLSQKNKLHN 183
                      46888999999998654116679************9333345667788899*************999987666 PP

>> PrmC_N  PrmC N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.2   5.6e-05      0.11      50      71 .]      67      88 ..      26      88 .. 0.85
   2 ?   -1.7   0.0       2.2   4.5e+03      22      41 ..     322     341 ..     312     343 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 5.6e-05
      PrmC_N 50 lerfeelierRaarePlqyIlG 71
                +++++++++ R +++PlqyIlG
  EEA18845.1 67 QQELRRMCAGRGRGKPLQYILG 88
                57899****************9 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 2.2
      PrmC_N  22 AelLlahvlglsrsdlllrg 41 
                 A+ L+++v ++ +++++++ 
  EEA18845.1 322 ARALFEKVGDIAKQRVYIWD 341
                 89999999999999998886 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   5.1e-05       0.1       7      43 ..     143     183 ..     137     237 .. 0.68

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 5.1e-05
  Methyltransf_12   7 tGsllrallekl....pdieytgvDispsaiedakeklakr 43 
                      +G ++  l   l    +d++++g+D++p+ai+  ++   ++
       EEA18845.1 143 SGCISLLLHSLLasdiKDLTIVGIDVDPQAIKLSQKNKLHN 183
                      4443333333334457***************3333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (362 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       397  (0.0221429); expected 358.6 (0.02)
Passed bias filter:                      387  (0.0215851); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.41
# Mc/sec: 2642.10
//
Query:       EEA18846.1  [L=783]
Description: glucose/galactose transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.5e-06   26.7  34.0    2.5e-06   26.7  34.0    4.2  4  MFS_1       Major Facilitator Superfamily
  ------ inclusion threshold ------
       0.13   12.2   3.4        3.8    7.5   0.1    3.9  3  MRAP        Melanocortin-2 receptor accessory protein family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?  -15.3  20.2         2   1.8e+04      66     106 ..      17      63 ..       3     214 .. 0.70
   2 !    8.9  12.5     7e-05      0.63     204     326 ..     370     489 ..     244     516 .. 0.66
   3 !   26.7  34.0   2.8e-10   2.5e-06       8     347 ..     383     724 ..     374     729 .. 0.67
   4 !    6.3  14.3   0.00044         4      61     181 ..     655     771 ..     655     778 .. 0.67

  Alignments for each domain:
  == domain 1  score: -15.3 bits;  conditional E-value: 2
       MFS_1  66 llglllfalglllllfa......sslwlllvlrvlqGlgagalfpag 106
                 ++g ++ ++ l+ ++f+      + + +ll+  + +G++ +++f++g
  EEA18846.1  17 FFGSVFVGFYLCSCIFVvkklrfADYLMLLAWFFDMGMAVCIFFALG 63 
                 22222222221111122344454555566666666666666666654 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 7e-05
       MFS_1 204 lkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailal.lagrlsdrlgrrrrlllallllllaalglallavtssav 301
                 + ++vl  l + ++l++f++ ++ +l   +  +   ls  +++ +l a+++ + +++++ l+  l+++lg   +l+ +l + +++al++ + av  s +
  EEA18846.1 370 VPPNVL--LTTLFFLWGFAYGLINVLNIRF-GSLTQLSP-WQTRGLHAAYFGGYMAGGIlLGRPLLKKLGFAGTLIAGLYIYACGALIFWPSAVRGSLP 464
                 222333..7777777765555544444445.88888883.33333333333333333440555566999998888888888888888888888889999 PP

       MFS_1 302 llllvlvliGfglgfvfpsllalas 326
                  ++++ +++G gl++  ++++ +++
  EEA18846.1 465 TFVVSNIVVGSGLALLETTANLFIA 489
                 9999999999999999999888776 PP

  == domain 3  score: 26.7 bits;  conditional E-value: 2.8e-10
       MFS_1   8 salarsilgpalplalaedlgispseigllltlyalgaavaslpl.GrlsdrfGrrrvlllglllfalglllllfa....sslwlllvlrvlqGlgaga 101
                  ++a+++++++     ++  ++sp +   l ++y+ g++++ ++l  +l  ++G   +l++gl ++a g+l+++ +     sl++++v+ ++ G g ++
  EEA18846.1 383 WGFAYGLINVLNI-RFGSLTQLSPWQTRGLHAAYFGGYMAGGILLgRPLLKKLGFAGTLIAGLYIYACGALIFW-PsavrGSLPTFVVSNIVVGSGLAL 479
                 3333333333333.333333344444445999******99999993568999*****************66666.224667777*************99 PP

       MFS_1 102 lfpagaaliadwfpkeergraigllsagfslGailg.pllggllasslg.......Wravfyilaivsllafvlfllllpeepperkrkspkeeekgtg 192
                 l ++++ +ia   p e     + +++++ ++G i++  l+  +l+ +          +++++++a+v++l+ v+ + +lp ++ ++   + +   ++++
  EEA18846.1 480 LETTANLFIAICGPLEYSEVRLCVAQSFQGIGDICAtELAQKALYKNPKdvaevvnAQWTYLAIAFVAVLLSVV-FYYLPLPEAPNDDLRRVAA-QRPE 576
                 999998888888888*********************55666688877779999999***************993.3444555555555555554.3333 PP

       MFS_1 193 paplvpawkallkdpvlwillialllfffgfsglltllpl..ylqevlgls....glllaglllallalvgailallagrls.drlgrrrrlllallll 284
                 +++ v    + ++ +    + ++l +++++f+ + +   l  + ++   +s    + +++  l a+++ v+ i++l +++++ + l++r++l++ +++ 
  EEA18846.1 577 NRAKVL---KYRTCN----VTFGLGVWSMFFYVAGQEAHLvnF-VDYVTYSdpssS-VSSNDLGAVGSTVWTIGRLATAFIMwKLLKPRWTLFILYIAS 666
                 333333...555555....444444444444443333333112.333333355552.55555689999999999********66688888888888888 PP

       MFS_1 285 llaalglallavtssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfntagsl 347
                 +++ ++++++    +av+++++++l   +++ +fp+l+a+ ++ +  ++a ta++l     + 
  EEA18846.1 667 IVFGALCIYTTGQ-TAVVMAMMVFL---FASGIFPILFAISVRGTA-QHAKTAASLLAASIGG 724
                 8888888888888.55555544444...444456777777777774.7777888877755553 PP

  == domain 4  score: 6.3 bits;  conditional E-value: 0.00044
       MFS_1  61 rrrvlllglllfalglllllfasslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyila 158
                 +r++l++ +++++++++l++++     + +v+ ++  l+a+++fp+  a+ ++ +++  +++  + l a++  G +++p +  + a s g ++++  + 
  EEA18846.1 655 PRWTLFILYIASIVFGALCIYT--TGqTAVVMAMMVFLFASGIFPILFAISVRGTAQ--HAKTAASLLAASIGGGAFAPFAQHAAAVSRGQPWSYSTIV 749
                 6998888888888886666643..33367888888888889999********99997..55555556666677778*******9999999888876555 PP

       MFS_1 159 ivsllafvlfllllpeepperkr 181
                 ++   a++ f+++l   p +++ 
  EEA18846.1 750 ALWSAAAI-FVVYLNFVPQAKRQ 771
                 55444444.33444444433333 PP

>> MRAP  Melanocortin-2 receptor accessory protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.5     0.039   3.5e+02      37      55 ..     198     216 ..     191     231 .. 0.81
   2 ?   -0.1   0.0       0.1   9.1e+02      38      67 ..     533     564 ..     526     594 .. 0.72
   3 ?    7.5   0.1   0.00042       3.8      35      56 ..     744     765 ..     739     768 .. 0.92

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.039
        MRAP  37 siviafWvsLavfvvllfl 55 
                  +++ f  s+a fv+l+ l
  EEA18846.1 198 KVILVFTFSVAIFVILVDL 216
                 5778899999999999754 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.1
        MRAP  38 iviafWvsLa.vfv.vllflvLlylsksGspq 67 
                 +v a W  La +fv vll +v+ yl    +p+
  EEA18846.1 533 VVNAQWTYLAiAFVaVLLSVVFYYLPLPEAPN 564
                 56677887774466366677777776665555 PP

  == domain 3  score: 7.5 bits;  conditional E-value: 0.00042
        MRAP  35 kysiviafWvsLavfvvllflv 56 
                  ys ++a+W + a fvv+l +v
  EEA18846.1 744 SYSTIVALWSAAAIFVVYLNFV 765
                 5999***************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (783 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       920  (0.0513135); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.71u 0.29s 00:00:01.00 Elapsed: 00:00:00.44
# Mc/sec: 5286.28
//
Query:       EEA18847.1  [L=484]
Description: aspartic-type endopeptidase (OpsB), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.3e-70  236.3   5.3    7.3e-70  235.9   5.3    1.2  1  Asp              Eukaryotic aspartyl protease
    1.1e-11   45.3   7.0    1.1e-10   42.0   7.0    2.5  1  TAXi_N           Xylanase inhibitor N-terminal
     0.0014   19.2   0.2        9.1    7.0   0.0    3.5  3  Asp_protease_2   Aspartyl protease
  ------ inclusion threshold ------
        0.1   12.4   0.0        1.6    8.5   0.0    2.4  1  TAXi_C           Xylanase inhibitor C-terminal


Domain annotation for each model (and alignments):
>> Asp  Eukaryotic aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  235.9   5.3   1.6e-73   7.3e-70       2     314 ..      68     398 ..      67     399 .. 0.90

  Alignments for each domain:
  == domain 1  score: 235.9 bits;  conditional E-value: 1.6e-73
                 EEEEEEETTTTEEEEEEEETT--SEEEEBTT...EST.SHCHHTSS-B-GGG-TT-EEEEEEEEEECTTS.EEEEEEEEEEEEETTEEEEEEEEEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp   2 YfgeisiGtpeqkftvifDTGSsdlWVpssk...ckk.ssackshstydpskSstykkngkslsisYGdg.svsGflsqdtvkvggltvknqefgeatk 95 
                 Y+ +i++Gtp q++++++DTGSsdlW    +   c+  s +c s  tydp++Ss+yk  +++++isY dg  + G +++dt +++g tv  ++fg   +
  EEA18847.1  68 YYCNITLGTPAQSLRLTLDTGSSDLWCNTPNstlCSSkSDQCASAGTYDPTSSSSYKYLSSNFNISYVDGtGAAGDYVTDTLTIAGATVSSFQFGVGYS 166
                 9*************************987776677766889*****************************99***********************9999 PP

                 ESSHHHTTSSSSEEEE-S-GGGSCGG...SCCHHHH....HHHTTSSSSSEEEEEE-STTSSEEEEEESSEEGGGEEEEEEEEEESS....TSSTEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxx RF
         Asp  96 epgstflaakfdGiLGlgfkeisvee...atpvfdn....lvsqglikepvfsvylnreeeeggeivfGgvDeskykGsltyvpvts....kgywqiel 183
                  ++       + G+LG+g+++ + +     +  + n    lv++gli+++++s++ln  ++++g+i+fGgvD+ ky G+l ++p+++     + + i +
  EEA18847.1 167 SSS-------NVGVLGIGYTSDEFQVsrdGEAAYANlpleLVNRGLINSNAYSLWLNDLDSNTGSILFGGVDSGKYIGELKTLPIQKeygdYAEFLIIM 258
                 888.......78********99877655677779999999***********************************************886656699999 PP

                 EEEEETTEEE...EEEEE..EEEEEETTCSSEEEEHHHHHHHHHHHTTEEEETTCEEEEETTGGGGSEEEEEEETTEEEEEEGGGGEEEESSS.....T CS
                 xxxxxxxxxx...xxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....x RF
         Asp 184 esvtvggktv...lcssg..cqailDtGTsllalptsivekiakaigakksesegeyvvdCdslsslpdisftiggakitvpvselvlkeees.....e 272
                 ++v +++++    ++s++    ++lD+GTsl++lp++iv++i +++g  +++s+g+  v C+ ++++ +i++t+ + +i v  selv++++++     +
  EEA18847.1 259 TGVALQTNSGdhsYSSDElpATVLLDSGTSLTYLPDNIVKDIYNDLGVVYESSTGTGYVPCSMMNENINITYTFTSPSIPVGISELVVEDGSGltfndG 357
                 999998877655544444114456****************************************************************99875222225 PP

                 TSEEEESEEECCTSSSEEEEHHHHTTEEEEEETTTTEEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp 273 esqCilglvseeegdlwiLGdvFlrsayvvfdldnnrvglAe 314
                 +  C++g+ ++ + ++  LGd+Flrsayvv+dl+nn+++lA+
  EEA18847.1 358 TPVCVFGI-APAGDSTATLGDTFLRSAYVVYDLANNEISLAP 398
                 579*****.999999*************************97 PP

>> TAXi_N  Xylanase inhibitor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.0   7.0   2.5e-14   1.1e-10       1     178 []      68     229 ..      68     229 .. 0.76

  Alignments for each domain:
  == domain 1  score: 42.0 bits;  conditional E-value: 2.5e-14
      TAXi_N   1 YlvsisiGtppqplklvvDtGsdltWvqCkpckacssqkkpvfdpsksstykavpcssslCkac.easssaksgsssstceyeisygadgssssGvlat 98 
                 Y+ +i +Gtp+q+l l++DtGs+ +W +                     +++  +++s++C++  +   +++s+ +  + +++isy  dg+ ++G+++t
  EEA18847.1  68 YYCNITLGTPAQSLRLTLDTGSSDLWCNT-------------------PNSTLCSSKSDQCASAgTYDPTSSSSYKYLSSNFNISYV-DGTGAAGDYVT 146
                 99************************998...................445566666666662222334444555556778899996.999******** PP

      TAXi_N  99 dtltlsstdgksvkvpnlvfGCgksnlgglaagadGilGLGrgk.............lSlvsqlaskg.slgnkFsyCLssssssssgvlffGd 178
                 dtlt+      +++v+++ fG g+s      ++  G+lG G+++               l+  l ++g + +n+ s+ L ++ +s++g ++fG+
  EEA18847.1 147 DTLTI-----AGATVSSFQFGVGYS-----SSSNVGVLGIGYTSdefqvsrdgeaayANLPLELVNRGlINSNAYSLWL-NDLDSNTGSILFGG 229
                 *****.....899***********3.....23357*******9977777777777777777777777655667777777.77777777777775 PP

>> Asp_protease_2  Aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0      0.17   7.5e+02       9      22 ..      80      93 ..      71     102 .. 0.82
   2 !    6.7   0.0    0.0025        11      45      88 ..     133     176 ..     120     178 .. 0.89
   3 !    7.0   0.0     0.002       9.1       7      31 ..     276     300 ..     271     340 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.17
  Asp_protease_2  9 pvrfllDTGasttl 22
                     +r+ lDTG+s + 
      EEA18847.1 80 SLRLTLDTGSSDLW 93
                    57899*****9875 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0025
  Asp_protease_2  45 sgaggevkarlvrldslklggltlknvpalvldlgeeidglLGm 88 
                     s ++g+  a  ++ d+l+++g+t+ ++++ v    ++  g+LG+
      EEA18847.1 133 SYVDGTGAAGDYVTDTLTIAGATVSSFQFGVGYSSSSNVGVLGI 176
                     6678999999999********************88999999996 PP

  == domain 3  score: 7.0 bits;  conditional E-value: 0.002
  Asp_protease_2   7 GkpvrfllDTGasttlispelaekl 31 
                     + p+++llD+G s t++++  ++++
      EEA18847.1 276 ELPATVLLDSGTSLTYLPDNIVKDI 300
                     5699**************9999876 PP

>> TAXi_C  Xylanase inhibitor C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.0   0.00036       1.6      31     158 ..     279     395 ..     256     398 .. 0.60

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00036
                 -SEEE-SSSSSEEE-H....HHHHHHHHHHHHTS-GG...GE---TT-S-EEETTS......-S----EEEEESSS-EEEE-GGGGEEE-SSSEEEE-E CS
      TAXi_C  31 ggtvlstgtpytvlet....dvYralvkafakelaaekvkrvaavkpfelCynsselgstragpavPtitlvleggaewtisgenllvkveggvvClaf 125
                 + ++l++gt++t+l++    d+Y+ l   +++++ +  v+    +++ +  y  ++          P+i +      e+ ++  + l +++g  vC+  
  EEA18847.1 279 ATVLLDSGTSLTYLPDnivkDIYNDLGVVYESSTGTGYVPCSMMNENINITYTFTS----------PSIPVGIS---ELVVEDGSGLTFNDGTPVCVFG 364
                 55666666666666541111334444444444444433332333333333333333..........55555554...6777777778888888888755 PP

                 EE--S--SSSEEE-HHHHBTS-EEEETTTTEEE CS
      TAXi_C 126 vesgvagesavviGglqlednllvFDleksrlg 158
                 +    ag+s++ +G   l+  ++v+Dl++++++
  EEA18847.1 365 IAP--AGDSTATLGDTFLRSAYVVYDLANNEIS 395
                 544..699********************99886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (484 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       527  (0.0293937); expected 358.6 (0.02)
Passed bias filter:                      345  (0.0192426); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 3267.56
//
Query:       EEA18848.1  [L=395]
Description: tryptophanyl-tRNA synthetase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-76  257.8   0.0    1.7e-76  257.4   0.0    1.1  1  tRNA-synt_1b  tRNA synthetases class I (W and Y)
  ------ inclusion threshold ------
      0.039   14.0   0.1       0.22   11.6   0.0    2.2  2  HTH_20        Helix-turn-helix domain


Domain annotation for each model (and alignments):
>> tRNA-synt_1b  tRNA synthetases class I (W and Y)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  257.4   0.0   1.9e-80   1.7e-76       7     291 ..      51     345 ..      46     347 .. 0.95

  Alignments for each domain:
  == domain 1  score: 257.4 bits;  conditional E-value: 1.9e-80
                   EEEEEEETSSS-BGG.GHHHHHHHHHHHH...TTSEEEEEEEHHHHHTTTTT-SSHHHHHHHHHHHHHHHHHHHHHTCHTTTEEEEETHHHHTTHHH CS
  tRNA-synt_1b   7 rvysGidPTgklHlG.ylvplkklvelqk...aghevffliaDlhAiigdpskaeerklrkreevlenaikaqlakgldpekaevvlqsewlehlel 99 
                    ++sGi+PTg +H+G yl++l+ +v+lq+   a+ +++  i+DlhA++g++s   + +lr+r+++  ++   +la+gldp k+ +++qs++ +h el
    EEA18848.1  51 VIFSGIQPTGIPHIGnYLGALREWVRLQNdagAKDKCIYSIVDLHALTGNQS---PHELRQRRKESFAM---LLAIGLDPRKSILFYQSDVSAHAEL 141
                   589***************************9999******************...**************...************************* PP

                   HHHHHHHHTTCBHHHHHHHHH.........CCHHCSSSC--BHHHHHHHHHHHHHHHHTCHSEEEEEGGGHHHHHHHHHHHHHHHHH...STTSS-E CS
  tRNA-synt_1b 100 aellrdlgklgslnrmlqfks.........vkkrleegegislgeftYplLqaaDilllkadlvpgGsDQkqnielgrdlarrfnkk...evfkkpe 184
                   +++l+ ++++g l+rm+q+ks          +++ ++ ++++lg+f+Yp+LqaaDil+  a++vp+G+DQkq+ie++r  a++fn++   ++f+ pe
    EEA18848.1 142 MWILSAVASMGYLSRMTQWKSklhlpedvdLENDTAK-SKLRLGLFSYPVLQAADILVHGATHVPVGEDQKQHIEFTRYTANSFNHRfdtDLFPAPE 237
                   *********************8887766554444444.79********************************************************* PP

                   EEEET...-BBSTTSSSBTTCETTC..GC-BTTCCHHHHHHHHHHCHCSTTCSHHHHHHHHHTHHHCHHHHHHHHCCSEEESSHHHHHHHHHCCCCH CS
  tRNA-synt_1b 185 gltvp...lltgldGekKmSKSagn..saIfLddekesvkkkiqkavtdsdeevekllklktelsnelierleavsgkkpkreaeellaeevtklvh 276
                   +l+ p   ++++ d+  KmSKS++   s+I L+d  ++v++ki++avtds+ ++ +++  ++++sn lie+l+++ + +  r++ee++ e+ +    
    EEA18848.1 238 ALISParrVMSLRDPIHKMSKSEEDkrSTILLNDTVKEVQQKIKQAVTDSEPGISYDPVRRPGISN-LIEILSHLEEPNG-RSCEEIASEFQST--R 330
                   *************************9****************************************.*******999887.*************..8 PP

                   HHHHHHHHHHHHHHH CS
  tRNA-synt_1b 277 ggdlkkalaealnel 291
                    +++k+ +++++n++
    EEA18848.1 331 IKAFKDHVEATINAH 345
                   99*******999986 PP

>> HTH_20  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.1      0.34   3.1e+03       5      13 ..     237     245 ..     232     247 .. 0.87
   2 ?   11.6   0.0   2.4e-05      0.22      14      46 ..     306     339 ..     304     340 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.34
                 HHHS-HHHH CS
      HTH_20   5 eALahPvRr 13 
                 eAL +P Rr
  EEA18848.1 237 EALISPARR 245
                 79******9 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 2.4e-05
                 HHHHHHSTCTTB-HHHHHHHH.TS-HHHHHHHHH CS
      HTH_20  14 rilraLaraegltaselaerl.dlskntlsyHLr 46 
                 +il++L ++ g++++e+a ++ +++ +   +H++
  EEA18848.1 306 EILSHLEEPNGRSCEEIASEFqSTRIKAFKDHVE 339
                 69*******************7799888999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (395 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       828  (0.0461822); expected 358.6 (0.02)
Passed bias filter:                      616  (0.0343577); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.42
# Mc/sec: 2842.26
//
Query:       EEA18849.1  [L=277]
Description: 37 ribosomal protein Rsm10, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.5e-29   99.5   0.0    1.9e-28   98.5   0.0    1.5  1  Ribosomal_S10  Ribosomal protein S10p/S20e


Domain annotation for each model (and alignments):
>> Ribosomal_S10  Ribosomal protein S10p/S20e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.5   0.0   1.1e-32   1.9e-28       2      97 ..     116     211 ..     115     212 .. 0.98

  Alignments for each domain:
  == domain 1  score: 98.5 bits;  conditional E-value: 1.1e-32
                    EEEEESSHHHHHHHHHHHHHHTTSSS-EE---EEEEEEEEEEEEE--SS--S--EEEEEEEEEEEEEEEE.E-HHHHHHHS-...S---SS-EEEE CS
  Ribosomal_S10   2 irlkSydsklLekavkkivraakelgikvkgpvplPtkrkrvtvlksphvdkksreqfeirthkRlidisdatketidtllkllqlnlpegVsvev 97 
                    ++l+Sy+ +++e ++++++raa++l+++v+gpvplP  ++r+tv +s++v+kks+e+fe+ t +Rli+i+d ++et++ +l +l+++   gV++++
     EEA18849.1 116 LQLRSYSVRNVEFFADFAIRAAYYLNLPVSGPVPLPRIVERWTVPRSNFVHKKSQENFERITLRRLIQIKDGHPETVQLWLAFLRRHAFYGVGMKA 211
                    89********************************************************************************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (277 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       437  (0.0243739); expected 358.6 (0.02)
Passed bias filter:                      361  (0.020135); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.29s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 1901.94
//
Query:       EEA18850.1  [L=231]
Description: purine nucleoside phosphorylase I, inosine and guanosine-specific [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
      2e-45  154.8   0.0    2.8e-45  154.4   0.0    1.1  1  PNP_UDP_1  Phosphorylase superfamily


Domain annotation for each model (and alignments):
>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  154.4   0.0   1.6e-49   2.8e-45      53     233 ..      11     221 ..       2     222 .. 0.93

  Alignments for each domain:
  == domain 1  score: 154.4 bits;  conditional E-value: 1.6e-49
                 HHHHHHHHHHHHHHHC--SEEEEEEEEEESSTTT-TT-EEEEEEEEE...SSSCCGCCTHHCC..TCCCCTTSSEE--HHHHHHHHHCHHTTT....TT CS
   PNP_UDP_1  53 kpnaavvaeirllkefgvkaiiriGtaGglnpdlkvGDvvipddain...fdgrsplygpkee..gqyfpdsydapadpelrallkeaaealg....ik 142
                 ++  +v++++r+lk +++++i+ +++aGglnp+++vGD+ + +d+i    ++g++pl+gp+ +  g++fp+ +da +d +lr+++++a++       ++
  EEA18850.1  11 HSIGDVTFPVRVLKLLEAETIVLTNAAGGLNPEYAVGDITVLNDHIFlagLSGLHPLRGPNVDefGVRFPPLSDA-YDLSLRRCVHNAWQSIAksetRR 108
                 4445599****************************************7778888888888888************.***********7666666778** PP

                 EEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTB......................ETTCTCH.HCCCHHHH CS
   PNP_UDP_1 143 vhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArelgipfaairvvsdlaag......................gadaeatheeveefaq 219
                 +h+Gv+a+++g+++et+ae+rllr+lgad+v+M+t+++ ++Ar++g++++a+++v+++a+                       + +++a+h+ev e+++
  EEA18850.1 109 LHEGVYAFVSGPSYETRAECRLLRNLGADVVGMSTVPEIIVARHAGMRVLAFSLVTNNAVLtpvprgddhllqstssgeldaiIKEGKADHQEVLEAGR 207
                 *********************************************************9999*************99999999999999999******** PP

                 HHHHHHHHHHHHHH CS
   PNP_UDP_1 220 eaaknaaalllall 233
                 +aa+++++l+ +++
  EEA18850.1 208 HAAQDMQRLVVQVI 221
                 **********9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (231 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       359  (0.0200234); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.22s 00:00:00.63 Elapsed: 00:00:00.38
# Mc/sec: 1837.04
//
Query:       EEA18851.1  [L=231]
Description: purine nucleoside phosphorylase I, inosine and guanosine-specific [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
      2e-45  154.8   0.0    2.8e-45  154.4   0.0    1.1  1  PNP_UDP_1  Phosphorylase superfamily


Domain annotation for each model (and alignments):
>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  154.4   0.0   1.6e-49   2.8e-45      53     233 ..      11     221 ..       2     222 .. 0.93

  Alignments for each domain:
  == domain 1  score: 154.4 bits;  conditional E-value: 1.6e-49
                 HHHHHHHHHHHHHHHC--SEEEEEEEEEESSTTT-TT-EEEEEEEEE...SSSCCGCCTHHCC..TCCCCTTSSEE--HHHHHHHHHCHHTTT....TT CS
   PNP_UDP_1  53 kpnaavvaeirllkefgvkaiiriGtaGglnpdlkvGDvvipddain...fdgrsplygpkee..gqyfpdsydapadpelrallkeaaealg....ik 142
                 ++  +v++++r+lk +++++i+ +++aGglnp+++vGD+ + +d+i    ++g++pl+gp+ +  g++fp+ +da +d +lr+++++a++       ++
  EEA18851.1  11 HSIGDVTFPVRVLKLLEAETIVLTNAAGGLNPEYAVGDITVLNDHIFlagLSGLHPLRGPNVDefGVRFPPLSDA-YDLSLRRCVHNAWQSIAksetRR 108
                 4445599****************************************7778888888888888************.***********7666666778** PP

                 EEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTB......................ETTCTCH.HCCCHHHH CS
   PNP_UDP_1 143 vhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArelgipfaairvvsdlaag......................gadaeatheeveefaq 219
                 +h+Gv+a+++g+++et+ae+rllr+lgad+v+M+t+++ ++Ar++g++++a+++v+++a+                       + +++a+h+ev e+++
  EEA18851.1 109 LHEGVYAFVSGPSYETRAECRLLRNLGADVVGMSTVPEIIVARHAGMRVLAFSLVTNNAVLtpvprgddhllqstssgeldaiIKEGKADHQEVLEAGR 207
                 *********************************************************9999*************99999999999999999******** PP

                 HHHHHHHHHHHHHH CS
   PNP_UDP_1 220 eaaknaaalllall 233
                 +aa+++++l+ +++
  EEA18851.1 208 HAAQDMQRLVVQVI 221
                 **********9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (231 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       359  (0.0200234); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.22s 00:00:00.66 Elapsed: 00:00:00.39
# Mc/sec: 1770.61
//
Query:       EEA18852.1  [L=227]
Description: nucleolus protein required for cell viability, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.5e-36  124.0   0.1    5.2e-36  122.9   0.1    1.5  1  Fcf2      Fcf2 pre-rRNA processing
  ------ inclusion threshold ------
      0.017   14.9   1.2      0.024   14.4   1.2    1.2  1  DUF4640   Domain of unknown function (DUF4640)


Domain annotation for each model (and alignments):
>> Fcf2  Fcf2 pre-rRNA processing
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  122.9   0.1   5.8e-40   5.2e-36       2      96 .]     109     202 ..     108     202 .. 0.96

  Alignments for each domain:
  == domain 1  score: 122.9 bits;  conditional E-value: 5.8e-40
        Fcf2   2 kktagkkWfnlpkteltpelkrdlqlLklrnvldpkrfyKkedkkkklPkyfqvGtivegetefysarltrkerkrtlveellkdeeakkyakrK 96 
                 +++ag++Wfn+pkt+lt elkrdlqlL++rnvldp+r+yKke + + +P+y+qvGtiveg+tef+++r+ +k+rk+t+vee+l+ e+ +  +k K
  EEA18852.1 109 EDNAGSDWFNMPKTRLTAELKRDLQLLRMRNVLDPHRHYKKE-SGNGIPEYSQVGTIVEGPTEFFKSRIVKKDRKQTFVEEVLAGEQQSGRFKAK 202
                 689***************************************.69*****************************************999988865 PP

>> DUF4640  Domain of unknown function (DUF4640)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   1.2   2.7e-06     0.024     134     234 ..      11     113 ..       4     127 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 2.7e-06
     DUF4640 134 ddedddsvlpesaqkEdfqlssssppdtaqvshqeedtc.qdlpkvkalenedviq.fpqipprlqerelaekisqatksqrtssletssvssgkpeee 230
                 +d d+d+ +++ +++ + +l sss++d   vs+ e  ++ qd+pk  +l     ++ f q+  ++   +  ++ s++  +  t  +  ++ ssgk++ e
  EEA18852.1  11 NDLDEDQYIQQLLNEAQARLRSSSSADNSLVSITETGVSaQDIPKIPKLSASAALKpFIQQSDEVATINNLQTVSPSVLDSTTNPVPRAAKSSGKEKAE 109
                 5779999*****************************9887*****9888877665537788888888889999***********************999 PP

     DUF4640 231 dtas 234
                 d+a 
  EEA18852.1 110 DNAG 113
                 9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (227 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       553  (0.0308439); expected 358.6 (0.02)
Passed bias filter:                      316  (0.0176251); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.23s 00:00:00.69 Elapsed: 00:00:00.43
# Mc/sec: 1596.58
//
Query:       EEA18853.1  [L=267]
Description: CCAAT-binding factor complex subunit HapE [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      7e-19   67.9   0.6    1.1e-18   67.2   0.6    1.3  1  CBFD_NFYB_HMF    Histone-like transcription factor (CBF/NF-Y)
    1.1e-15   58.2   0.2    1.8e-15   57.5   0.2    1.3  1  Histone          Core histone H2A/H2B/H3/H4
  ------ inclusion threshold ------
      0.039   14.3   0.0      0.085   13.2   0.0    1.6  1  CENP-X           CENP-S associating Centromere protein X
        1.4    9.0   5.2       0.67   10.0   0.6    2.0  2  G_path_suppress  G-protein pathway suppressor


Domain annotation for each model (and alignments):
>> CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) and archaeal histone
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.2   0.6   2.5e-22   1.1e-18       2      65 .]      86     149 ..      85     149 .. 0.98

  Alignments for each domain:
  == domain 1  score: 67.2 bits;  conditional E-value: 2.5e-22
                    XXXHHHHHHHHHCCTTXS-B-HHHHHHHHHHHHHHHHHHHHHHHHHHCCTTSSCE-HHHHHHHH CS
  CBFD_NFYB_HMF   2 eLPiarvkkImksdpdarkiakdAkeliaecveefieelaseAaeickkekrKtikaehiklAv 65 
                    +LP+ar+kk+mk dp++++i+ +A++l+a+ +  fi+el+ +A+ +++++kr+t+++ +i+ A+
     EEA18853.1  86 QLPLARIKKVMKADPEVKMISAEAPILFAKGCDIFITELTMRAWIHAEDNKRRTLQRSDIAAAL 149
                    69***********************************************************997 PP

>> Histone  Core histone H2A/H2B/H3/H4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.5   0.2     4e-19   1.8e-15      57     128 ..      79     149 ..      72     152 .. 0.96

  Alignments for each domain:
  == domain 1  score: 57.5 bits;  conditional E-value: 4e-19
                 XXSXXSXHHHHHHHHHHHH.TTSSSXEEXHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTXSEEXHHHHHHHH CS
     Histone  57 stdlliqklpfaRvvreivksekedlrisaeavlalqealEallvelfeeAnllakhaKRvTitpkDiqlAr 128
                 + d +i++lp aR +++++k + e ++isaea+ ++++ +  +++el+++A++ a+++KR+T+++ Di +A+
  EEA18853.1  79 NHDYKIHQLPLAR-IKKVMKADPEVKMISAEAPILFAKGCDIFITELTMRAWIHAEDNKRRTLQRSDIAAAL 149
                 6789*********.*******************************************************997 PP

>> CENP-X  CENP-S associating Centromere protein X
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   1.9e-05     0.085      18      53 ..     104     139 ..      89     161 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.9e-05
                 EE-CCCHHHHHHHHHHHHHHHHHHHHHHHHHTT-SE CS
      CENP-X  18 kItkdalelvaeylklFvrEavaRaaeeaeeegkee 53 
                  I+ +a  l+a+  ++F++E  +Ra ++ae+++ ++
  EEA18853.1 104 MISAEAPILFAKGCDIFITELTMRAWIHAEDNKRRT 139
                 48999999*******************999988776 PP

>> G_path_suppress  G-protein pathway suppressor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.3     0.066   2.9e+02     163     208 ..       3      49 ..       1     107 [. 0.68
   2 ?   10.0   0.6   0.00015      0.67      86     215 ..     131     265 ..     126     267 .] 0.54

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.066
  G_path_suppress 163 qpalspgyaeksqqksdegr..aear..vstnkslaqYppsgqlfyptva 208
                      q++ s+g+ ++ qq+  + r  +  +  +s   s+  Y+p  +  y+++ 
       EEA18853.1   3 QATQSSGQQQNRQQAVYDIRngG--HygASAALSAQGYAPVAE-LYTGAW 49 
                      66666777777777777777431..223555555567888887.565533 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00015
  G_path_suppress  86 nEdekRkrqlKEqselaalqqaaa.qvflpqvqqrqkllsmqgsphhqqrlqk.............pgpqvnvlkrkrspsppqltqayykqpa 165
                      + +++++r l   s++aa  + +    fl  +  r++  s  +         +             +g   ++  +++ p+++  +q+++  p 
       EEA18853.1 131 HAEDNKRRTLQR-SDIAAALAKSDmFDFLIDIVPREEATSHAK---------RssqaggavgtagaAGASGSAGAAGHIPAAQAGVQHPHMAPE 214
                      645555554555.466655333222344555333333322221.........111123333445556667777899****************** PP

  G_path_suppress 166 lspgyaeksqqksdegrae.ar..vstnkslaqYppsgql....fyptvaphqklpp 215
                      +  + a ++    +++r + +   ++++  +a Y +++      +y++++    +pp
       EEA18853.1 215 YLGQHALAQD---QDYRNQpGMypGAVQSDPAAYGQPQPQmfdgMYTAYPH---MPP 265
                      9877766555...44552222234666666789999988844555544332...333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (267 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       674  (0.0375927); expected 358.6 (0.02)
Passed bias filter:                      507  (0.0282782); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 1731.60
//
Query:       EEA18854.1  [L=766]
Description: Exocyst complex component Sec15, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
     1e-111  373.4   1.8     1e-111  373.4   1.8    2.4  2  Sec15           Exocyst complex subunit Sec15-like
    4.7e-05   23.3   4.5    4.7e-05   23.3   4.5    2.6  3  Sec8_exocyst    Sec8 exocyst complex component specific domai
    0.00061   20.0   9.8      0.011   15.9   6.8    3.4  3  COG5            Golgi transport complex subunit 5
     0.0026   17.8   5.9     0.0026   17.8   5.9    2.7  2  COG2            COG (conserved oligomeric Golgi) complex comp
     0.0053   16.6  10.8      0.038   13.8   3.9    3.1  3  Sec5            Exocyst complex component Sec5
  ------ inclusion threshold ------
      0.036   14.2   5.0      0.096   12.8   1.9    3.2  2  Vps51           Vps51/Vps67
      0.052   13.9   1.3       0.33   11.2   0.0    2.9  3  Mre11_DNA_bind  Mre11 DNA-binding presumed domain
       0.08   12.9   0.1        1.9    8.5   0.0    2.9  2  PUB             PUB domain
       0.14   12.6   2.5       0.81   10.2   1.0    2.9  2  KELK            KELK-motif containing domain of MRCK Ser/Thr 
       0.15   11.3  11.8       0.05   12.9   7.8    2.0  2  Vps54_N         Vacuolar-sorting protein 54, of GARP complex
       0.67   10.3   7.2         16    5.9   0.0    3.9  4  DUF3510         Domain of unknown function (DUF3510)
        2.1    8.8  10.2         13    6.2   5.1    3.9  3  MitMem_reg      Maintenance of mitochondrial structure and fu


Domain annotation for each model (and alignments):
>> Sec15  Exocyst complex subunit Sec15-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.3      0.38   5.7e+02     109     219 ..     128     242 ..     123     247 .. 0.65
   2 !  373.4   1.8  6.7e-115    1e-111       1     316 []     444     743 ..     444     743 .. 0.97

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.38
                 HHHHHTTS---S.......TTT--TT----THHHHHHHH..HHHHHHHHHHHHHHHHT....------------------.----HHHHHHHHHHHIII CS
       Sec15 109 ackelekllaqerssqrggnieqnsaeeiklkaskkfke..arkaAekkifelvdsKi....ddflelaeydWtpteaes.epseylkdliqfLetifs 200
                 +++ l++ l  +r s++ + +  ++++ + l+a +++++   ++ ++ ki el++  +      + e +  d ++   +  e s+yl +++ + +++ +
  EEA18854.1 128 SLRALQDCLEVLRLSNQVHDLLGKKNHYAALRALEELQNvhLKEITQYKISELIQRSVpatqRAIAEAVMSDLNTWLYRIrEMSQYLGEIALYHTNLRK 226
                 566677777777777778777888888888888888886325788888888888887722222334444445444333334778888888877777777 PP

                 IIITTS-SSTTTTHHHHTT CS
       Sec15 201 svlvnLpesvkelvyfral 219
                 +    L+e +++l y++ +
  EEA18854.1 227 E---RLKERAQNLGYLEQF 242
                 6...566777777766665 PP

  == domain 2  score: 373.4 bits;  conditional E-value: 6.7e-115
                 HHHHHHHT---------------------------SSHHHHHHHHHHHHHHHT---SSS-STTTTTHHHHHHHS-SSTGGGHHHHHHH--.-STTTTTT CS
       Sec15   1 YekvlkvcwlkeseleeaeekesefpvtlPFSqlyplcCidirkfieklykFledlyqhereiddilrksldeLLirvvseklrsklkstlnleqiaQi 99 
                 ++kv++v+w++++++     +e++fp++lPFSq+yplcCidir+f++++y F++d ++h   id++l+++ld+LL++ v+e+l+++l+s+ +l qi+Qi
  EEA18854.1 444 FDKVINVSWYTPEKPR----EEQTFPCVLPFSQMYPLCCIDIRNFLNQFYFFSNDDFSHADVIDETLKTALDDLLSNEVCETLVERLSSQ-YLGQIVQI 537
                 79**********7544....4679*****************************9999*********************************.******** PP

                 THHHHTTTHHHHHHTTS---S.......TTT--TT----THHHHHHHHHHHHHHHHHHHHHHHHT----------------------HHHHHHHHHHHI CS
       Sec15 100 liNleyfetackelekllaqerssqrggnieqnsaeeiklkaskkfkearkaAekkifelvdsKiddflelaeydWtpteaesepseylkdliqfLeti 198
                 liNle+fe ac+ele ll+++rs+++          +++lka++kf++++kaAek+ife v+sKidd++e+aeydWtpt +++eps+y+++l++fL++i
  EEA18854.1 538 LINLEHFEMACQELEALLVAARSQASTA-------GPVSLKATEKFRNNKKAAEKRIFEVVNSKIDDLIETAEYDWTPTVEPEEPSNYMQTLTRFLSNI 629
                 ********************87777663.......58************************************************************** PP

                 IIIIITTS-SSTTTTHHHHTTTHHHHHHHHHTTS---S--SSSHHHHHHTTTSSGGG-----------------------TTTT.TTT--S.SHHHHHH CS
       Sec15 199 fssvlvnLpesvkelvyfraldhiaeslldlllseevkrineeavenlelDvkylesfakslsvskkeeslestfaelrqlidLllsdnveeYldpsir 297
                 ++s+l+ Lp+++kel+yf+al+h a+++l+l+ls+ev++in  +v++l+ Dv+yl +f++sl+++     l++ ++el+q+++Ll sdn +e++d+s+r
  EEA18854.1 630 MNSTLLGLPTEIKELIYFDALSHAANEILALPLSPEVRKINPYGVTALAKDVEYLATFVDSLNNP----ILRENLDELQQTVNLLQSDNSDEFYDISTR 724
                 ***************************************************************99....9**************77************* PP

                 HHSS-SS-TTTTTTTTTHH CS
       Sec15 298 erkYsrvkpekaaklleKl 316
                 ++kY rv++ ++++lleKl
  EEA18854.1 725 NKKYGRVDAMNGPILLEKL 743
                 ******************7 PP

>> Sec8_exocyst  Sec8 exocyst complex component specific domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.3   4.5   3.1e-08   4.7e-05      43     141 ..      49     147 ..      30     148 .. 0.93
   2 ?   -2.6   0.1       3.1   4.6e+03     115     141 ..     527     553 ..     504     554 .. 0.78
   3 ?   -2.9   0.1       3.9   5.9e+03      42      63 ..     573     594 ..     570     598 .. 0.83

  Alignments for each domain:
  == domain 1  score: 23.3 bits;  conditional E-value: 3.1e-08
  Sec8_exocyst  43 kefkqlkkqieeaLqevvnehhqaFnssiasYskilssiqesqekvselKesleeakkklstkkkeLkelnarsakykevieiLdaieelkkvpdki 139
                   ++++ + ++ e++++++ n++hq F +s+     i +   + ++++ +l +s++++++kl ++kk L e   + ++ +e ++ L+   e+ ++ +++
    EEA18854.1  49 RSLSRFASDKEQEIENICNTNHQEFVTSVNQLLRIREGTVSLTSEILDLNQSIQSSTEKLAEQKKALVESRSHRQNIDESLRALQDCLEVLRLSNQV 145
                   567778888999*******************************************************************************999999 PP

  Sec8_exocyst 140 eq 141
                   ++
    EEA18854.1 146 HD 147
                   86 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 3.1
  Sec8_exocyst 115 rsakykevieiLdaieelkkvpdkieq 141
                   +s+ + ++++iL ++e+ +   +++e+
    EEA18854.1 527 SSQYLGQIVQILINLEHFEMACQELEA 553
                   467778999999999999888887775 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 3.9
  Sec8_exocyst  42 lkefkqlkkqieeaLqevvneh 63 
                    ++f++ kk  e+ + evvn  
    EEA18854.1 573 TEKFRNNKKAAEKRIFEVVNSK 594
                   5789999999999999999975 PP

>> COG5  Golgi transport complex subunit 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0         2     3e+03     113     125 ..      42      54 ..      25      56 .. 0.87
   2 !   15.9   6.8   7.3e-06     0.011      46     132 .]      59     145 ..      48     145 .. 0.96
   3 ?    2.5   0.0       0.1   1.5e+02      77     112 ..     696     731 ..     685     747 .. 0.75

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 2
                 HHHHHHHHHHHHH CS
        COG5 113 hqtldLlrralrf 125
                  qt++Llr+++rf
  EEA18854.1  42 NQTSQLLRSLSRF 54 
                 599******9998 PP

  == domain 2  score: 15.9 bits;  conditional E-value: 7.3e-06
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        COG5  46 dkrlrqlitsnhleLlehlskskslssvlselksslesLsasyerlkskvlepyeeaeklqsalkrlhqtldLlrralrflhlskqL 132
                 ++++++++++nh+e  + +++ +  ++ + +l+s++ +L++s++  ++k+ e  + + +++s  +++ ++l+ l + l +l+ls+q+
  EEA18854.1  59 EQEIENICNTNHQEFVTSVNQLLRIREGTVSLTSEILDLNQSIQSSTEKLAEQKKALVESRSHRQNIDESLRALQDCLEVLRLSNQV 145
                 789*********************************************************************************995 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.1
                 XXXXXXXXXXXXXXXX-TTHHHHHHHHHHHHHHHHH CS
        COG5  77 lksslesLsasyerlkskvlepyeeaeklqsalkrl 112
                 l+++l++L++ ++ l+s+ ++ ++++++++++  r+
  EEA18854.1 696 LRENLDELQQTVNLLQSDNSDEFYDISTRNKKYGRV 731
                 567777777777777777777777777777766665 PP

>> COG2  COG (conserved oligomeric Golgi) complex component, COG2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   5.9   1.8e-06    0.0026      27     132 ..      43     148 ..      35     149 .. 0.88
   2 ?   -2.2   0.1       2.8   4.2e+03      81     102 ..     572     594 ..     550     605 .. 0.56

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 1.8e-06
        COG2  27 pLeslrrdLeaylkllekellelvnedyadFvslSghLvglqeeleevesplaaarkkvesvreklsereeeveskleeakeleekrellklllkldev 125
                 +  +l r L  +++  e+e+ ++ n++ ++Fv   ++L  ++e    ++s+++ + + ++s +ekl+e+++++ +  + ++++ e  + l++ l++ ++
  EEA18854.1  43 QTSQLLRSLSRFASDKEQEIENICNTNHQEFVTSVNQLLRIREGTVSLTSEILDLNQSIQSSTEKLAEQKKALVESRSHRQNIDESLRALQDCLEVLRL 141
                 56789999999***********************************************************99988888888888888888888888888 PP

        COG2 126 vekleal 132
                  +++ +l
  EEA18854.1 142 SNQVHDL 148
                 7887776 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 2.8
        COG2  81 arkkvesvreklsereeev.esk 102
                 a++k+++++++ ++r+ ev +sk
  EEA18854.1 572 ATEKFRNNKKAAEKRIFEVvNSK 594
                 44455555554444443321333 PP

>> Sec5  Exocyst complex component Sec5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.8   3.9   2.5e-05     0.038      39     150 ..      64     209 ..      39     230 .. 0.82
   2 !    5.7   0.2    0.0077        12      27      97 ..     574     645 ..     569     658 .. 0.83
   3 ?   -1.9   0.0       1.6   2.4e+03      45      82 ..     677     712 ..     654     734 .. 0.62

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2.5e-05
        Sec5  39 d...........................slveeLeeslneairkttllfkpvlenkekadklraaleviernkflFnLPksLkesiakgdydklindYk 110
                 +                           s + +L++s++++++k  +  k ++e+++  +++   l+ ++   +++ L++++++ + k+++  +++  +
  EEA18854.1  64 NicntnhqefvtsvnqllriregtvsltSEILDLNQSIQSSTEKLAEQKKALVESRSHRQNIDESLRALQDCLEVLRLSNQVHDLLGKKNHYAALRALE 162
                 233344444444444444445555555566789****************************************************************** PP

        Sec5 111 kakslfestrqslv.......eedkkqvkvfkkvwsevekiieeyrk 150
                 + +++  ++  +++       +  ++q  +++ v+s+ ++   ++r+
  EEA18854.1 163 ELQNVHLKEITQYKiseliqrSVPATQRAIAEAVMSDLNTWLYRIRE 209
                 99999999998888999999888999999999999999998888876 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.0077
        Sec5  27 kefseskteaqedslveeLeeslneairkttllfkpvlenkekadklraalevier..nkflFnLPksLkesi 97 
                 ++f+++k++a++  + e ++++++++i++++   +p +e +e ++ +++ +++++   n+ l+ LP ++ke i
  EEA18854.1 574 EKFRNNKKAAEKR-IFEVVNSKIDDLIETAEYDWTPTVEPEEPSNYMQTLTRFLSNimNSTLLGLPTEIKELI 645
                 6788777776666.55999999999999999999999999999999999999998655899999999999866 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 1.6
        Sec5  45 Leeslneairkttllfkpvlenkekadklraalevier 82 
                 L + ++ +++  ++l +p+l ++   d+l+++++++++
  EEA18854.1 677 LAKDVEYLATFVDSLNNPILRENL--DELQQTVNLLQS 712
                 555555555555555555554332..444444444443 PP

>> Vps51  Vps51/Vps67
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   1.9   6.4e-05     0.096      23      86 ..      43     106 ..      27     132 .. 0.93
   2 ?   -0.2   0.1       0.7     1e+03      18      33 ..     697     712 ..     688     717 .. 0.56

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 6.4e-05
       Vps51  23 ellkveasllseiraldselkalVydnYskLisasdtIrkmksemdkldqklselkqaiskiae 86 
                 ++ ++ +sl + + ++++e+ +++ +n++++++  +++ ++++ + +l +++ +l+q+i++ +e
  EEA18854.1  43 QTSQLLRSLSRFASDKEQEIENICNTNHQEFVTSVNQLLRIREGTVSLTSEILDLNQSIQSSTE 106
                 66778889999999*********************************************99877 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.7
       Vps51  18 kstlkellkveaslls 33 
                 +++l+el+++ + l+s
  EEA18854.1 697 RENLDELQQTVNLLQS 712
                 3444444444444444 PP

>> Mre11_DNA_bind  Mre11 DNA-binding presumed domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.3       1.4     2e+03     124     153 ..     116     157 ..      85     195 .. 0.64
   2 ?   -3.7   0.0       8.7   1.3e+04     131     152 ..     371     392 ..     361     401 .. 0.74
   3 ?   11.2   0.0   0.00022      0.33      19      70 ..     568     623 ..     564     630 .. 0.82

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 1.4
                     X...............XXXXXXXXXCHHHHHHHHHHS....X CS
  Mre11_DNA_bind 124 e.........eeellaeaekldklkvedlVkeyleaqe...k 153
                               +e+l a ++ l+ l++++ V+++l +++    
      EEA18854.1 116 VesrshrqniDESLRALQDCLEVLRLSNQVHDLLGKKNhyaA 157
                     123333445555666666666667777777777776654443 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 8.7
                     XXXXXXXXXCHHHHHHHHHHS. CS
  Mre11_DNA_bind 131 eaekldklkvedlVkeyleaqe 152
                      +++++ lk+++l++ +++a++
      EEA18854.1 371 VDNAESLLKIKNLIALFMQAMD 392
                     4455556999999999999986 PP

  == domain 3  score: 11.2 bits;  conditional E-value: 0.00022
                     EECCC-TTT-.CCTS-CCCHHHHHHHHHHHHHHHHHHHH...SSSTTS------EE CS
  Mre11_DNA_bind  19 isLsdvaelk.kkeknkekvtkflrekVeelieeaeeew...eeeaeeeepplPLi 70 
                     +sL+ +++++ +k+++++++ +++++k+++lie ae +w    e +e+++ ++ L 
      EEA18854.1 568 VSLKATEKFRnNKKAAEKRIFEVVNSKIDDLIETAEYDWtptVEPEEPSNYMQTLT 623
                     8899999988899999999********************77655566666666555 PP

>> PUB  PUB domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0      0.41   6.2e+02       6      20 ..     617     631 ..     612     634 .. 0.85
   2 ?    8.5   0.0    0.0013       1.9       8      52 ..     647     711 ..     644     712 .. 0.95

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.41
         PUB   6 ealktLrkylnNile 20 
                 ++++tL + l+Ni++
  EEA18854.1 617 NYMQTLTRFLSNIMN 631
                 7899*********97 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0013
         PUB   8 lktLrkylnNilehpteekyrrI....................rleNkafkekvlplegavelLe 52 
                 ++ L   +n il  p  +  r+I                    +l+N++++e+++ l+++v+lL+
  EEA18854.1 647 FDALSHAANEILALPLSPEVRKInpygvtalakdveylatfvdSLNNPILRENLDELQQTVNLLQ 711
                 677888999******************************************************98 PP

>> KELK  KELK-motif containing domain of MRCK Ser/Thr protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0      0.87   1.3e+03      66      80 .]      49      63 ..      39      63 .. 0.81
   2 ?   10.2   1.0   0.00054      0.81      10      63 ..      88     141 ..      79     148 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.87
        KELK 66 qklsRqlrdkeeEle 80
                + lsR   dke E+e
  EEA18854.1 49 RSLSRFASDKEQEIE 63
                469999*******97 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.00054
        KELK  10 rllkqEkeelqkelaeaqErlksqkkeLkdaisqrklamqefsevneklselrs 63 
                  +l++E  +l++ ++ + E+l +qkk L +  s+r+   + ++ +++ l+ lr 
  EEA18854.1  88 VSLTSEILDLNQSIQSSTEKLAEQKKALVESRSHRQNIDESLRALQDCLEVLRL 141
                 568889999****************************99999999988877765 PP

>> Vps54_N  Vacuolar-sorting protein 54, of GARP complex
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   7.8   3.4e-05      0.05      49     190 ..      60     202 ..      24     259 .. 0.88
   2 ?   -0.8   0.1      0.49   7.3e+02      63     113 ..     528     579 ..     492     611 .. 0.57

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 3.4e-05
     Vps54_N  49 kklsqlilekreefvkelseveeiekelkesvvickngrraLdlakkeltrtsLellakskkrqllkkllktltaikelrelekrleelleeedysaAi 147
                 + + +    +++efv  ++++  i++   + + ++ +  + +++++++l++ +  l+ ++  rq   + l+ l++  e+ +l +++++ll ++++ aA+
  EEA18854.1  60 QEIENICNTNHQEFVTSVNQLLRIREGTVSLTSEILDLNQSIQSSTEKLAEQKKALVESRSHRQNIDESLRALQDCLEVLRLSNQVHDLLGKKNHYAAL 158
                 4566667789***************************************************************************************** PP

     Vps54_N 148 qllletkql.aekysqyncvqelssklqetlelveekldsqLse 190
                   l e +++ +++  qy+  + +++++ +t   + e + s+L++
  EEA18854.1 159 RALEELQNVhLKEITQYKISELIQRSVPATQRAIAEAVMSDLNT 202
                 ******99737899999998889999999999988888888876 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.49
     Vps54_N  63 vkelseveeiekelkesvvickngrraLdlakkeltrts.Lellakskkrql 113
                 ++ l+++ +i  +l++    c++    L  a++++++     l a +k r+ 
  EEA18854.1 528 SQYLGQIVQILINLEHFEMACQELEALLVAARSQASTAGpVSLKATEKFRNN 579
                 4556677777777777777777777777777766655432455555555543 PP

>> DUF3510  Domain of unknown function (DUF3510)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   1.0      0.79   1.2e+03      37     105 ..      45     118 ..      25     138 .. 0.58
   2 ?   -1.9   0.0       2.8   4.1e+03      40      67 ..     158     185 ..     119     218 .. 0.53
   3 ?    5.3   0.1     0.017        25      49      94 ..     505     550 ..     480     587 .. 0.72
   4 ?    5.9   0.0     0.011        16      19      68 ..     602     651 ..     573     660 .. 0.75

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.79
     DUF3510  37 seilkplktf..kkesekk.lseevleewlaevle..evtsrYletisevlssvkkteesLkrlkkarkgaaas 105
                 s++l+ l++f  +ke+e + + +   +e++++v +  ++ +  ++ +se+l+  +  ++s ++l +++k+  +s
  EEA18854.1  45 SQLLRSLSRFasDKEQEIEnICNTNHQEFVTSVNQllRIREGTVSLTSEILDLNQSIQSSTEKLAEQKKALVES 118
                 56677777774422222222333335555555533114445555666666666666666666666666655544 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 2.8
     DUF3510  40 lkplktfkkesekklseevleewlaevl 67 
                 l+ l+++++ + k++++  ++e++++ +
  EEA18854.1 158 LRALEELQNVHLKEITQYKISELIQRSV 185
                 3444444333333344444333333333 PP

  == domain 3  score: 5.3 bits;  conditional E-value: 0.017
     DUF3510  49 esekklseevleewlaevleevtsrYletisevlssvkkteesLkr 94 
                 + ++ l++ + +e++++ +e+++s+Yl +i ++l + +  e   + 
  EEA18854.1 505 TLKTALDDLLSNEVCETLVERLSSQYLGQIVQILINLEHFEMACQE 550
                 34444778888999********************999988855443 PP

  == domain 4  score: 5.9 bits;  conditional E-value: 0.011
     DUF3510  19 rlyRrtnkevptepSkyvseilkplktfkkesekk.lseevleewlaevle 68 
                 ++y +t    p+epS+y++++ + l+++ +++    l+ e+ e +  ++l+
  EEA18854.1 602 AEYDWTPTVEPEEPSNYMQTLTRFLSNIMNSTL-LgLPTEIKELIYFDALS 651
                 5677777788*****************743333.33777776665555555 PP

>> MitMem_reg  Maintenance of mitochondrial structure and function
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   5.1    0.0087        13      19      68 ..     189     242 ..      25     268 .. 0.92
   2 ?   -2.8   0.0       5.7   8.5e+03      21     102 ..     521     536 ..     504     546 .. 0.53
   3 ?   -0.3   0.0      0.96   1.4e+03      34      79 ..     675     717 ..     608     749 .. 0.73

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0087
  MitMem_reg  19 s....stlstglnrqyyslkilqerldlikdYlkkveegelpvnheilrnlqkl 68 
                 +    ++++++ln+ +y ++ +++ l +i  Y+ ++ +++l+  ++ l +l ++
  EEA18854.1 189 QraiaEAVMSDLNTWLYRIREMSQYLGEIALYHTNLRKERLKERAQNLGYLEQF 242
                 1235689*********************************98877777777654 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 5.7
  MitMem_reg  21 tlstglnrqyyslkilqerldlikdYlkkveegelpvnheilrnlqkllnllPhleteelekefnvetnDvllvvyLasltr 102
                 tl+++l++                                                                   yL+++++
  EEA18854.1 521 TLVERLSS------------------------------------------------------------------QYLGQIVQ 536
                 44444444..................................................................44444444 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.96
  MitMem_reg  34 kilqerldlikdYlkkveegelpvnheilrnlqkllnllPhletee 79 
                 + l + ++ +  +++++     p+  e l +lq+++nll   +++e
  EEA18854.1 675 TALAKDVEYLATFVDSLN---NPILRENLDELQQTVNLLQSDNSDE 717
                 445555555666666666...4666888888888888887555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (766 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1210  (0.0674884); expected 358.6 (0.02)
Passed bias filter:                      597  (0.033298); expected 358.6 (0.02)
Passed Vit filter:                        70  (0.00390429); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.76u 0.31s 00:00:01.07 Elapsed: 00:00:00.49
# Mc/sec: 4716.88
//
Query:       EEA18855.1  [L=624]
Description: meiosis protein MEI2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.5e-32  109.1   0.4    1.7e-31  108.3   0.4    1.4  1  RRM_2     RNA recognition motif 2
    8.5e-10   38.3   0.6      0.038   13.8   0.0    3.4  3  RRM_1     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom
  ------ inclusion threshold ------
       0.15   11.4   0.0        3.9    6.9   0.0    2.4  2  DUF4926   Domain of unknown function (DUF4926)


Domain annotation for each model (and alignments):
>> RRM_2  RNA recognition motif 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  108.3   0.4   2.9e-35   1.7e-31       1      97 []     432     522 ..     432     522 .. 0.98

  Alignments for each domain:
  == domain 1  score: 108.3 bits;  conditional E-value: 2.9e-35
       RRM_2   1 rttlliknipnkytkkmllaaideknkgtydflylpidfknkcnvgyafinlvepkkivafqkafngkkwekfnsekvaslayariqgkaaliaklq 97 
                 rtt++++nipnk    +l++ +de++ g+ydf+yl+idf n cnvgyafin+        f +a++g+ w+ fns+kva+++ya iqg++ li+k++
  EEA18855.1 432 RTTIMLRNIPNKVDLSLLKTIVDETSFGKYDFMYLRIDFANNCNVGYAFINFE------DFVEARAGHTWNCFNSDKVAEVSYATIQGRDCLIQKFR 522
                 8**************************************************96......599********************************996 PP

>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.5   0.0   0.00061       3.7       6      59 ..     162     214 ..     157     220 .. 0.79
   2 !   13.8   0.0   6.4e-06     0.038      18      66 ..     270     317 ..     258     321 .. 0.82
   3 !   13.7   0.1   7.1e-06     0.042       1      53 [.     435     490 ..     435     491 .. 0.94

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.00061
                 ETTTSSHHHHHHHHHT..TSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHH CS
       RRM_1   6 LppdvteeeLkelFsk..fGpiksiklvrdetgkskgfafVeFeskedAekAleal 59 
                 ++p +++ ++  +Fs   fG+i+   l+     ks g   VeF++ +d ++Ale+ 
  EEA18855.1 162 VSPAISHLTVASIFSRreFGSIQGPYLSEL---KSLGKFVVEFTDLRDTQRALEKI 214
                 556666666667776555999988888887...999999**************975 PP

  == domain 2  score: 13.8 bits;  conditional E-value: 6.4e-06
                 HHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEETT CS
       RRM_1  18 lFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkklgg 66 
                 l + fG  +s+k++  + ++ k+f +VeF +  dA++A++ lng  +++
  EEA18855.1 270 LVKSFGTLVSFKIPFLQADNIKKF-YVEFCDTTDAANAVAVLNGAVIEN 317
                 4566***********766666666.*******************99987 PP

  == domain 3  score: 13.7 bits;  conditional E-value: 7.1e-06
                 EEEESETTTSSHHHHHHHHHT..TSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHH CS
       RRM_1   1 lfVgnLppdvteeeLkelFsk..fGpiksiklvrd.etgkskgfafVeFeskedAe 53 
                 ++++n+p+ v+ + Lk++  +  fG++    l  d +++ + g+af++Fe+  +A+
  EEA18855.1 435 IMLRNIPNKVDLSLLKTIVDEtsFGKYDFMYLRIDfANNCNVGYAFINFEDFVEAR 490
                 6789***************9999****999*********************99987 PP

>> DUF4926  Domain of unknown function (DUF4926)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.0     0.026   1.5e+02      33      49 ..     196     212 ..     188     218 .. 0.75
   2 ?    6.9   0.0   0.00066       3.9      32      56 ..     291     315 ..     283     317 .. 0.84

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.026
     DUF4926  33 aYeVEFsdddGeTlall 49 
                 ++ VEF+d      al+
  EEA18855.1 196 KFVVEFTDLRDTQRALE 212
                 79******877666665 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.00066
     DUF4926  32 eaYeVEFsdddGeTlalltLseeql 56 
                 +++ VEF+d +  + a+  L+   +
  EEA18855.1 291 KKFYVEFCDTTDAANAVAVLNGAVI 315
                 789**************99987665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (624 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       331  (0.0184617); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.44
# Mc/sec: 4241.30
//
Query:       EEA18856.1  [L=484]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.2e-19   68.5   0.1    1.3e-18   67.2   0.1    1.6  1  adh_short        short chain dehydrogenase
    2.5e-08   33.8   0.1    2.1e-07   30.8   0.1    2.1  2  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    4.7e-06   26.6   1.4    0.00011   22.2   1.4    2.2  1  KR               KR domain
  ------ inclusion threshold ------
      0.028   13.5   0.0      0.044   12.9   0.0    1.3  1  Polysacc_synt_2  Polysaccharide biosynthesis protein
       0.17   11.3   0.1       0.47    9.9   0.1    1.7  1  Epimerase        NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.2   0.1   3.6e-22   1.3e-18       1     172 [.      31     192 ..      31     200 .. 0.92

  Alignments for each domain:
  == domain 1  score: 67.2 bits;  conditional E-value: 3.6e-22
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCSH CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvv.vdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfselse 98 
                 k++l+tG+++ IG  i + +a +G + ++ v+r +e l+ +a el++    +  +++D        a+++ ++k+++++d +v NAG   ++ + el++
  EEA18856.1  31 KTILITGGGGEIGVGITRSFAVAGSTQIAiVGRWQEVLASTARELENP---FKGLKID--------AAFDLVIKEFEPIDDFVDNAGYISVELATELDS 118
                 79**********************999988****************85...7776655........679****************************** PP

                 HHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGG.TSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTE CS
   adh_short  99 eewervievNltgvflltravlpamlkqssGrIvnvsSvag.kvpvagvaaYsAsKaavagltrslakelaptgi 172
                 +   +v+++N+ g + ++ a+ ++  ++  + ++ vsS+a+   p  g+aaYsAsK a + + + +a e  ++++
  EEA18856.1 119 DGAWAVFATNMSGSIYTVWAFSRT-ERRDHAVVIDVSSIAAiIPPIHGGAAYSASKLAATNIWEYFAAENPSHRV 192
                 **99********************.9***************445667789**************99999998875 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.8   0.1   5.7e-11   2.1e-07      55     159 ..      83     187 ..      42     192 .. 0.92
   2 ?    0.8   0.0      0.08   2.9e+02     189     225 ..     194     230 ..     184     233 .. 0.75

  Alignments for each domain:
  == domain 1  score: 30.8 bits;  conditional E-value: 5.7e-11
                   HHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHHHHHHHHTHHHHHHHHHHHHHCTSC.CEEEEEEEGGGTSB.STTTTHHHHHHHHHH CS
  adh_short_C2  55 qvealveevvekfgklDilvnnagiapklkgpfletsreefdraldvnlyslfllakaalplmkeg.gsivnlssvgaerv.vpnynaygaaKaale 149
                   +++a+++ v ++f+ +D +v nag+     + ++e++ ++   ++++n+ + ++++ a+ +  ++  + ++ +ss++a +  + + +ay+a+K a  
    EEA18856.1  83 KIDAAFDLVIKEFEPIDDFVDNAGYISV--ELATELDSDGAWAVFATNMSGSIYTVWAFSRTERRDhAVVIDVSSIAAIIPpIHGGAAYSASKLAAT 177
                   5899************************..9999***************************77766599999****99988788888********** PP

                   HHHHHHHHHH CS
  adh_short_C2 150 altrylAvel 159
                   ++  y+A+e 
    EEA18856.1 178 NIWEYFAAEN 187
                   *******985 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.08
                   HHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SE CS
  adh_short_C2 189 leelearaplgrlgtpeevaeaalfLasdeasyitGq 225
                   + e+ +++ l+ +  ++  ++ a++Las+ea +  G+
    EEA18856.1 194 ETEMTKSIGLKGADHVDLPGQFAVWLASPEADFLHGK 230
                   5556666666666666666899***********9995 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.2   1.4     3e-08   0.00011       2     153 ..      32     173 ..      31     198 .. 0.76

  Alignments for each domain:
  == domain 1  score: 22.2 bits;  conditional E-value: 3e-08
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT- CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklleem 100
                 t litGG G +G  ++r  a  g +++++++R +   e  +++ +el   +   + +++D        a+++ + +e++pi   +  Ag +  +l +e+
  EEA18856.1  32 TILITGGGGEIGVGITRSFAVAGSTQIAIVGRWQ---EVLASTAREL---ENPFKGLKID--------AAFDLVIKEFEPIDDFVDNAGYISVELATEL 116
                 679******************************3...2333334444...5577777777........45566666667******************** PP

                 -HHHHHHHHTTTTHHHHHHHHHTTT.S--SEEEE..EEEHHHHH-.-TT-HHHHHHH CS
          KR 101 taedleqvlapKvkGawnLhelled.esldffvl..fSSiagllg.sagqanYaaaN 153
                 +++   +v+a  ++G+     ++++ e+ d+ v+  +SSia+++    g a+Y+a  
  EEA18856.1 117 DSDGAWAVFATNMSGSIYTVWAFSRtERRDHAVVidVSSIAAIIPpIHGGAAYSASK 173
                 ***************9876666655455565554238*****886145677777754 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   1.2e-05     0.044       1      56 [.      33      88 ..      33     104 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.2e-05
                     EEEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH......-TTEEEE. CS
  Polysacc_synt_2  1 vlvtGagGsiGselvrqilkkkpkkiillerdElklyeiekeleeelkkkklkvei 56
                     +l+tG+gG iG  ++r ++    ++i ++ r    l + ++ele+ +k  k+++ +
       EEA18856.1 33 ILITGGGGEIGVGITRSFAVAGSTQIAIVGRWQEVLASTARELENPFKGLKIDAAF 88
                     89*****************************9999999999998888877776554 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.1   0.00013      0.47       1     165 [.      33     193 ..      33     210 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00013
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHCEEEE--TT-HHHHHHHHHHHT-SEEEE--S---HHHHHHSHHHHHHHHTHHHHHHH CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledlelveldltdrsalerlfkeeqpdavihlAavggvaassedpadfieknlqgtlnll 99 
                 il+tG+ G iG  +++ ++ +g + i++  +             + e+    + +le+ fk  ++da + l     v  ++e   df+++   ++++l+
  EEA18856.1  33 ILITGGGGEIGVGITRSFAVAGSTQIAIVGR-------------WQEVLASTARELENPFKGLKIDAAFDL-----VIKEFEPIDDFVDNAGYISVELA 113
                 89********************886666666.............457777888899999999999999999.....77889999999999999999999 PP

                 HHHHHHTCT.EEEEEEEGGGGT.........SCSS..SS.BSTCSTTS----SSHHHHHHHHHHHHHHHHHHHH.T-EEE CS
   Epimerase 100 eaarkagvk.rllflsSsevYG.........kdae..qp.keettltgplkpnspYaaaKlageklveayaaqy.glnai 165
                  ++   g+   +    S ++Y          +d+   +   +  +   p++   +Y+a+Kla+ ++ e++aa++   ++i
  EEA18856.1 114 TELDSDGAWaVFATNMSGSIYTvwafsrterRDHAvvIDvSSIAAIIPPIHGGAAYSASKLAATNIWEYFAAENpSHRVI 193
                 99999988756666678889988888888774444333333333334455999*****************9998555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (484 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       809  (0.0451224); expected 358.6 (0.02)
Passed bias filter:                      573  (0.0319594); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.42
# Mc/sec: 3427.38
//
Query:       EEA18857.1  [L=853]
Description: transferase (Gpi7), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.4e-14   51.9   2.0    9.4e-09   35.3   0.1    2.2  2  Phosphodiest    Type I phosphodiesterase / nucleotide pyropho
    0.00041   19.9   0.1      0.011   15.1   0.0    2.1  2  Sulfatase       Sulfatase
  ------ inclusion threshold ------
      0.015   14.7   0.0      0.026   13.9   0.0    1.3  1  Metalloenzyme   Metalloenzyme superfamily
       0.13   12.8   0.1       0.52   10.9   0.1    2.0  2  Inhibitor_G39P  Loader and inhibitor of phage G40P
       0.17   10.4   0.1       0.24   10.0   0.1    1.1  1  DUF229          Protein of unknown function (DUF229)


Domain annotation for each model (and alignments):
>> Phosphodiest  Type I phosphodiesterase / nucleotide pyrophosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.2   1.8e-06    0.0065       1      59 [.      54     113 ..      54     121 .. 0.93
   2 !   35.3   0.1   2.6e-12   9.4e-09     159     237 ..     184     262 ..     137     275 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 1.8e-06
                   EEEEEETT-BTTHHHHHGS..TSHHHHHHHHHSEEESE.EE-SSS-SHHHHHHHHHHSS-HH CS
  Phosphodiest   1 vlvislDGlradlldrlae..llpnlaaLakegvsapn.lrpvfPtlTfpnhaslvTGlyPg 59 
                   v+++++D lr d ++   +     + + L+++g   p   +++ Pt+T+p   ++ TG+ P+
    EEA18857.1  54 VILMVVDALRSDFVYS--NnsGFVFTQDLIRTGAAWPFtAHASSPTVTMPRIKAITTGSVPS 113
                   79************99..446****************************************7 PP

  == domain 2  score: 35.3 bits;  conditional E-value: 2.6e-12
                   CHTHSHHHHHCT......SSESEEEEEECCCHHHHHHH-TTSHHHHHHHHHHHHHHHHHHHHHHHTTGTTTEEEEEEES---EEE CS
  Phosphodiest 159 aafakvvlekel......ekpdlllvyleetDtvgHkfGpdspevedalrrvDkaigdLlealderglsaetniilvSDHGmadv 237
                   + +++             +++ ++++++ ++D++gHk Gp+s+ +  + r+ D  ++++++a+  +   ++t ++l++DHGm++ 
    EEA18857.1 184 NVTRH------VspelaqDDWSVMVLHYLGLDHIGHKAGPKSSHMIPKQREMDGIVEEIYNAMLSETHLDSTLLVLLGDHGMNEA 262
                   22222......1234456******************************************9987776668888*********986 PP

>> Sulfatase  Sulfatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0     0.021        76       3      81 ..      54     132 ..      52     142 .. 0.75
   2 !   15.1   0.0   3.2e-06     0.011     219     309 .]     227     326 ..     225     326 .. 0.78

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.021
                 EEEEEESSE-TTGSGGGTTTSCSSHHHHHHHHTSEEESSEE-SSSSHHHHHHHHHHSS-HHHHTHSSCCSTTT.HHCTTT CS
   Sulfatase   3 vvliladdlgagdlglyggktattpnldrlaeeglrftnfysaaplcspsraalltgryphnsgvasntevgg.gglpqt 81 
                 v+l ++d l+++ + +++     t+ l   +   + ft + s+ +++ p   a+ tg  p  s+v+ n    +  +   +
  EEA18857.1  54 VILMVVDALRSDFVYSNNSGFVFTQDLI-RTGAAWPFTAHASSPTVTMPRIKAITTGSVPSFSDVVLNIAESEsMSTLIH 132
                 7788888888887777766666677774.4688899*************************9999888765555444444 PP

  == domain 2  score: 15.1 bits;  conditional E-value: 3.2e-06
                 HHHHHHHHHHHHHHHHTTTGGGEEEEEEESSSSCCCGHHTTSSSCTTCSSSHHHHBEEEEEEETTTSHC...............EEECSEEE...GGGH CS
   Sulfatase 219 eyvDdligrvlaaLeenglldntlvvftSDhgasleesngplrggkganayeggtrvPllvwwpgekap...............rvseelvs...hiDl 299
                 +++D  ++++++a   +  ld tl+v ++Dhg    e      +g++   +  g   P+l   + ++++               + + e+++   ++D+
  EEA18857.1 227 REMDGIVEEIYNAMLSETHLDSTLLVLLGDHGMN--E------AGNH-GGSSAGETSPALTFISPKLQKhsenselkgrdspieAENFEFYHtveQSDI 316
                 58******************************93..3......3333.3334788889999888888888888888666665554444444489999** PP

                 HHHHHHHTTE CS
   Sulfatase 300 fptildlagi 309
                 +pt+++l+g+
  EEA18857.1 317 TPTLAGLLGV 326
                 ******9996 PP

>> Metalloenzyme  Metalloenzyme superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   7.2e-06     0.026     118     191 ..     184     263 ..     173     291 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 7.2e-06
                    HHHHHHHHHH.CC.-SEEEEEE-HHHHHHHTT-HH..HHHHHHHHHHHHHHHHHTTS-T....TTEEEEEE-SSB--TTT CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxx RF
  Metalloenzyme 118 evaekaldailsgkfdlvvvniknaDmvGHtgdle..atiaaieaaDeavkeildaieq....vdgilvvtADHgnaedm 191
                    +v++++  ++ +++ +++v+++   D +GH+  ++    i    ++D +v+ei +a+ +    + ++lv+++DHg  e  
     EEA18857.1 184 NVTRHVSPELAQDDWSVMVLHYLGLDHIGHKAGPKssHMIPKQREMDGIVEEIYNAMLSethlDSTLLVLLGDHGMNEAG 263
                    6788888999999999***************87761156788889********99986511225679********98865 PP

>> Inhibitor_G39P  Loader and inhibitor of phage G40P
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.1   0.00015      0.52       3      26 ..     355     378 ..     353     384 .. 0.84
   2 ?   -2.3   0.0       1.9   6.7e+03       4      16 ..     800     812 ..     798     833 .. 0.72

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00015
  Inhibitor_G39P   3 reetikiLavlkaaYPrfyngrsk 26 
                      e+t++i +v+k aYP+f  + +k
      EEA18857.1 355 LENTVQIQNVIKMAYPKFSTNGDK 378
                     689***************877665 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1.9
  Inhibitor_G39P   4 eetikiLavlkaa 16 
                     + t+++Lav+ a+
      EEA18857.1 800 NTTMELLAVMAAC 812
                     77999****9998 PP

>> DUF229  Protein of unknown function (DUF229)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.1   6.6e-05      0.24     312     370 ..     227     283 ..     172     326 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 6.6e-05
      DUF229 312 ealDedllkylkklekkgllentlvlllsDHGlrfgklrktsqGilEerlPlmlirlPp 370
                 + +D  + ++  ++  +  l+ tl++ll+DHG++   + +      +e  P + ++ P+
  EEA18857.1 227 REMDGIVEEIYNAMLSETHLDSTLLVLLGDHGMNE--AGNHGGSSAGETSPALTFISPK 283
                 5568888888889999999*************853..3333333344555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (853 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       759  (0.0423336); expected 358.6 (0.02)
Passed bias filter:                      343  (0.019131); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.73u 0.30s 00:00:01.03 Elapsed: 00:00:00.50
# Mc/sec: 5140.15
//
Query:       EEA18858.1  [L=852]
Description: transferase (Gpi7), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.4e-14   51.9   2.0    9.4e-09   35.3   0.1    2.2  2  Phosphodiest    Type I phosphodiesterase / nucleotide pyropho
     0.0004   19.9   0.1      0.011   15.1   0.0    2.1  2  Sulfatase       Sulfatase
  ------ inclusion threshold ------
      0.015   14.7   0.0      0.026   13.9   0.0    1.3  1  Metalloenzyme   Metalloenzyme superfamily
       0.13   12.8   0.1       0.52   10.9   0.1    2.0  2  Inhibitor_G39P  Loader and inhibitor of phage G40P
       0.17   10.4   0.1       0.24   10.0   0.1    1.1  1  DUF229          Protein of unknown function (DUF229)


Domain annotation for each model (and alignments):
>> Phosphodiest  Type I phosphodiesterase / nucleotide pyrophosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.2   1.8e-06    0.0065       1      59 [.      54     113 ..      54     121 .. 0.93
   2 !   35.3   0.1   2.6e-12   9.4e-09     159     237 ..     184     262 ..     137     275 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 1.8e-06
                   EEEEEETT-BTTHHHHHGS..TSHHHHHHHHHSEEESE.EE-SSS-SHHHHHHHHHHSS-HH CS
  Phosphodiest   1 vlvislDGlradlldrlae..llpnlaaLakegvsapn.lrpvfPtlTfpnhaslvTGlyPg 59 
                   v+++++D lr d ++   +     + + L+++g   p   +++ Pt+T+p   ++ TG+ P+
    EEA18858.1  54 VILMVVDALRSDFVYS--NnsGFVFTQDLIRTGAAWPFtAHASSPTVTMPRIKAITTGSVPS 113
                   79************99..446****************************************7 PP

  == domain 2  score: 35.3 bits;  conditional E-value: 2.6e-12
                   CHTHSHHHHHCT......SSESEEEEEECCCHHHHHHH-TTSHHHHHHHHHHHHHHHHHHHHHHHTTGTTTEEEEEEES---EEE CS
  Phosphodiest 159 aafakvvlekel......ekpdlllvyleetDtvgHkfGpdspevedalrrvDkaigdLlealderglsaetniilvSDHGmadv 237
                   + +++             +++ ++++++ ++D++gHk Gp+s+ +  + r+ D  ++++++a+  +   ++t ++l++DHGm++ 
    EEA18858.1 184 NVTRH------VspelaqDDWSVMVLHYLGLDHIGHKAGPKSSHMIPKQREMDGIVEEIYNAMLSETHLDSTLLVLLGDHGMNEA 262
                   22222......1234456******************************************9987776668888*********986 PP

>> Sulfatase  Sulfatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0     0.021        76       3      81 ..      54     132 ..      52     142 .. 0.75
   2 !   15.1   0.0   3.2e-06     0.011     219     309 .]     227     326 ..     225     326 .. 0.78

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.021
                 EEEEEESSE-TTGSGGGTTTSCSSHHHHHHHHTSEEESSEE-SSSSHHHHHHHHHHSS-HHHHTHSSCCSTTT.HHCTTT CS
   Sulfatase   3 vvliladdlgagdlglyggktattpnldrlaeeglrftnfysaaplcspsraalltgryphnsgvasntevgg.gglpqt 81 
                 v+l ++d l+++ + +++     t+ l   +   + ft + s+ +++ p   a+ tg  p  s+v+ n    +  +   +
  EEA18858.1  54 VILMVVDALRSDFVYSNNSGFVFTQDLI-RTGAAWPFTAHASSPTVTMPRIKAITTGSVPSFSDVVLNIAESEsMSTLIH 132
                 7788888888887777766666677774.4688899*************************9999888765555444444 PP

  == domain 2  score: 15.1 bits;  conditional E-value: 3.2e-06
                 HHHHHHHHHHHHHHHHTTTGGGEEEEEEESSSSCCCGHHTTSSSCTTCSSSHHHHBEEEEEEETTTSHC...............EEECSEEE...GGGH CS
   Sulfatase 219 eyvDdligrvlaaLeenglldntlvvftSDhgasleesngplrggkganayeggtrvPllvwwpgekap...............rvseelvs...hiDl 299
                 +++D  ++++++a   +  ld tl+v ++Dhg    e      +g++   +  g   P+l   + ++++               + + e+++   ++D+
  EEA18858.1 227 REMDGIVEEIYNAMLSETHLDSTLLVLLGDHGMN--E------AGNH-GGSSAGETSPALTFISPKLQKhsenselkgrdspieAENFEFYHtveQSDI 316
                 58******************************93..3......3333.3334788889999888888888888888666665554444444489999** PP

                 HHHHHHHTTE CS
   Sulfatase 300 fptildlagi 309
                 +pt+++l+g+
  EEA18858.1 317 TPTLAGLLGV 326
                 ******9996 PP

>> Metalloenzyme  Metalloenzyme superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   7.2e-06     0.026     118     191 ..     184     263 ..     173     291 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 7.2e-06
                    HHHHHHHHHH.CC.-SEEEEEE-HHHHHHHTT-HH..HHHHHHHHHHHHHHHHHTTS-T....TTEEEEEE-SSB--TTT CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxx RF
  Metalloenzyme 118 evaekaldailsgkfdlvvvniknaDmvGHtgdle..atiaaieaaDeavkeildaieq....vdgilvvtADHgnaedm 191
                    +v++++  ++ +++ +++v+++   D +GH+  ++    i    ++D +v+ei +a+ +    + ++lv+++DHg  e  
     EEA18858.1 184 NVTRHVSPELAQDDWSVMVLHYLGLDHIGHKAGPKssHMIPKQREMDGIVEEIYNAMLSethlDSTLLVLLGDHGMNEAG 263
                    6788888999999999***************87761156788889********99986511225679********98865 PP

>> Inhibitor_G39P  Loader and inhibitor of phage G40P
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.1   0.00015      0.52       3      26 ..     355     378 ..     353     384 .. 0.84
   2 ?   -2.3   0.0       1.9   6.7e+03       4      16 ..     799     811 ..     797     832 .. 0.72

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00015
  Inhibitor_G39P   3 reetikiLavlkaaYPrfyngrsk 26 
                      e+t++i +v+k aYP+f  + +k
      EEA18858.1 355 LENTVQIQNVIKMAYPKFSTNGDK 378
                     689***************877665 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1.9
  Inhibitor_G39P   4 eetikiLavlkaa 16 
                     + t+++Lav+ a+
      EEA18858.1 799 NTTMELLAVMAAC 811
                     77999****9998 PP

>> DUF229  Protein of unknown function (DUF229)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.1   6.6e-05      0.24     312     370 ..     227     283 ..     172     326 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 6.6e-05
      DUF229 312 ealDedllkylkklekkgllentlvlllsDHGlrfgklrktsqGilEerlPlmlirlPp 370
                 + +D  + ++  ++  +  l+ tl++ll+DHG++   + +      +e  P + ++ P+
  EEA18858.1 227 REMDGIVEEIYNAMLSETHLDSTLLVLLGDHGMNE--AGNHGGSSAGETSPALTFISPK 283
                 5568888888889999999*************853..3333333344555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (852 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       760  (0.0423894); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.65u 0.30s 00:00:00.95 Elapsed: 00:00:00.43
# Mc/sec: 5950.97
//
Query:       EEA18859.1  [L=120]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    3.5e-22   78.4   1.0    3.5e-22   78.4   1.0    2.4  2  DUF2423     Protein of unknown function (DUF2423)
  ------ inclusion threshold ------
       0.15   11.0  10.8       0.18   10.8  10.8    1.0  1  Peroxin-3   Peroxin-3
       0.68    9.1   4.5       0.94    8.6   4.5    1.2  1  TRAP_alpha  Translocon-associated protein (TRAP), alpha subun


Domain annotation for each model (and alignments):
>> DUF2423  Protein of unknown function (DUF2423)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.4   1.0   5.8e-26   3.5e-22       1      44 []       1      44 [.       1      44 [. 0.99
   2 ?    0.9   1.1     0.091   5.5e+02       7      17 ..      83      93 ..      81     110 .. 0.62

  Alignments for each domain:
  == domain 1  score: 78.4 bits;  conditional E-value: 5.8e-26
     DUF2423  1 MAKSlRSkskkraravkRksvFgpvedaRteRLsaKLkelakkp 44
                MAKS+RS++kkr++a++R++vFgpv+daRteRLsaKL+ela++p
  EEA18859.1  1 MAKSIRSSTKKRNHAKLRSTVFGPVVDARTERLSAKLQELAAQP 44
                ******************************************97 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.091
     DUF2423  7 Skskkraravk 17
                S+ ++++r +k
  EEA18859.1 83 SSKQRSNRVRK 93
                45555555554 PP

>> Peroxin-3  Peroxin-3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8  10.8   2.9e-05      0.18      79     169 ..      29     116 ..      19     120 .] 0.66

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 2.9e-05
   Peroxin-3  79 dvEeitqeLqqkkaeraarsseakseeekssaspsvededdskslseeesssssstvsasseassseesaseeseksekeseessskprks 169
                  +E+++++Lq+ +a+ ++ ++++   ee+++++ ++ede+d+ ++ e+++++sss+ + s+   ++++ +++++   +k    ++ k+rk+
  EEA18859.1  29 RTERLSAKLQELAAQPLKIETTKDAAEENTKTEVEAEDESDKMAIDESATTQSSSSKQRSNRVRKQPKRKPRNTMVFAKP---HQGKQRKT 116
                 689************99998888777776666666666666777776666677666666666666666555555544443...23333332 PP

>> TRAP_alpha  Translocon-associated protein (TRAP), alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   4.5   0.00016      0.94      25      90 ..      49     114 ..      31     119 .. 0.51

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00016
  TRAP_alpha  25 aaaaaeedevddelvdveaedeeveeeeeee.eeeeeeeeedee..elkaspdadttilFtkpvekaee 90 
                 ++++a+e+++    ++veaede+ ++  +e+ ++++++ ++ ++  + +++ +   t++F kp ++++ 
  EEA18859.1  49 TTKDAAEENT---KTEVEAEDESDKMAIDESaTTQSSSSKQRSNrvRKQPKRKPRNTMVFAKPHQGKQR 114
                 2333333333...44455544444433333303333344444441155555566789******976654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (120 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2292  (0.127838); expected 358.6 (0.02)
Passed bias filter:                      597  (0.033298); expected 358.6 (0.02)
Passed Vit filter:                        64  (0.00356964); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 875.62
//
Query:       EEA18860.1  [L=531]
Description: SUMO ligase SizA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      3e-42  144.4   0.1    5.6e-42  143.5   0.1    1.5  1  PINIT           PINIT domain
    5.5e-23   80.4   6.8    9.7e-23   79.7   6.8    1.4  1  zf-MIZ          MIZ/SP-RING zinc finger
    5.6e-08   32.4   0.6    1.4e-07   31.0   0.0    2.0  2  SAP             SAP domain
      1e-06   28.4   3.1    2.3e-06   27.3   3.1    1.6  1  zf-Nse          Zinc-finger of the MIZ type in Nse subunit
  ------ inclusion threshold ------
      0.092   12.8   2.8       0.26   11.4   2.8    1.8  1  zf-Sec23_Sec24  Sec23/Sec24 zinc finger
        1.2    9.3   5.8        2.4    8.4   5.8    1.5  1  zf-C3HC4_4      zinc finger of C3HC4-type, RING


Domain annotation for each model (and alignments):
>> PINIT  PINIT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  143.5   0.1   1.9e-45   5.6e-42       2     146 .]     120     257 ..     119     257 .. 0.95

  Alignments for each domain:
  == domain 1  score: 143.5 bits;  conditional E-value: 1.9e-45
       PINIT   2 lrfkkspFYeileelskpteleasskkrnsvsfsfklseeqveklakssrkekrvqyqlrlfcased.sksesseeqdiefPpqleikvNgkevkanlr 99 
                 l fk+spFY+ile ls+++e+++++++r++v+++f+ls+  +++l +++++     +++++fca+++    ++ ++ di+fP+q+e+k N ++vkanlr
  EEA18860.1 120 LMFKESPFYKILEPLSSTVECKVREQTRDTVELKFTLSSTTAQRL-QEDPN-----LRVMVFCAADSgL--NQFSKSDIAFPYQVELKANLDDVKANLR 210
                 68********************99*********************.999**.....*******987663..345789********************** PP

       PINIT 100 glknkpGtarPvditkllrlspaetNrieityaltkkkYylvvylVk 146
                 glkn+pG++rP+dit+++r+++++tN + +t+alt+kk+y+vv+lVk
  EEA18860.1 211 GLKNRPGSTRPADITSYIRKRAGYTNLVAMTFALTQKKFYVVVNLVK 257
                 **********************************************8 PP

>> zf-MIZ  MIZ/SP-RING zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.7   6.8   3.2e-26   9.7e-23       1      49 [.     299     347 ..     299     348 .. 0.98

  Alignments for each domain:
  == domain 1  score: 79.7 bits;  conditional E-value: 3.2e-26
                 EESB-TTTSSB-SSEEEETT--SS--EEHHHHHHHHHHS---B-TTT-- CS
      zf-MIZ   1 vslkCplslsrikiPvrgekCkHlqCfdlesylelnertetWnCPvCsk 49 
                 +slkCpls+ ri+iP+r++ C+H+qCfd++s+l+l+e+++tW CPvC+k
  EEA18860.1 299 MSLKCPLSTLRIEIPCRSISCTHNQCFDASSFLQLQEQAPTWTCPVCNK 347
                 79*********************************************98 PP

>> SAP  SAP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.0   0.0   4.9e-11   1.4e-07       1      35 []      14      48 ..      14      48 .. 0.96
   2 ?   -2.1   0.1       1.2   3.5e+03       6      16 ..     261     271 ..     261     271 .. 0.79

  Alignments for each domain:
  == domain 1  score: 31.0 bits;  conditional E-value: 4.9e-11
                HTT--HHHHHHHHHHTT--TTS-HHHHHHHHHHHH CS
         SAP  1 lskltVaeLKeeLkkrGLptsGkKaeLieRLkeyl 35
                ++++t a+ Ke+L++ GL++sG+K  L+ RL+ey+
  EEA18860.1 14 IKTMTNAQMKEALRSEGLAVSGVKISLQLRLIEYI 48
                589******************************96 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.2
                 HHHHHHHHHHT CS
         SAP   6 VaeLKeeLkkr 16 
                 V eL ++Lk+r
  EEA18860.1 261 VEELVAALKSR 271
                 67888889887 PP

>> zf-Nse  Zinc-finger of the MIZ type in Nse subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   3.1   7.8e-10   2.3e-06       2      57 .]     291     346 ..     290     346 .. 0.93

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 7.8e-10
                 XXXXXSSBXXSB-TTTSSB-SSEEEESSS--..EEEHHHHHHHCTTTS-EE-SCCC-S CS
      zf-Nse   2 elaieeerislkCPltlqpfeePvtskkCpH..vFEreaIlelikrkktvkCPvagCs 57 
                 +++ ++  +slkCPl+   +e P +s  C H   F+ ++ l+l ++ +t  CPv  C+
  EEA18860.1 291 DIVATSTVMSLKCPLSTLRIEIPCRSISCTHnqCFDASSFLQLQEQAPTWTCPV--CN 346
                 77888899***********************666********************..86 PP

>> zf-Sec23_Sec24  Sec23/Sec24 zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   2.8   8.6e-05      0.26      13      35 ..     329     351 ..     314     353 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 8.6e-05
  zf-Sec23_Sec24  13 pfckidfggkrwiCnfCnhknev 35 
                      f + ++++ +w+C+ Cn+++ +
      EEA18860.1 329 SFLQLQEQAPTWTCPVCNKSTSF 351
                     577889*************9987 PP

>> zf-C3HC4_4  zinc finger of C3HC4-type, RING
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   5.8   0.00079       2.4      13      42 .]     316     345 ..     303     345 .. 0.89

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00079
  zf-C3HC4_4  13 sleCGhsfClsCisslqkepdgeqllCplC 42 
                 s++C h+ C+   s lq ++++  ++Cp+C
  EEA18860.1 316 SISCTHNQCFDASSFLQLQEQAPTWTCPVC 345
                 8*******************9*99****** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (531 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       867  (0.0483574); expected 358.6 (0.02)
Passed bias filter:                      662  (0.0369234); expected 358.6 (0.02)
Passed Vit filter:                        77  (0.00429472); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.42
# Mc/sec: 3803.01
//
Query:       EEA18861.1  [L=354]
Description: sterol delta 5,6-desaturase ERG3 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.3e-25   90.3  16.7    1.3e-25   90.3  16.7    2.2  2  FA_hydroxylase  Fatty acid hydroxylase superfamily


Domain annotation for each model (and alignments):
>> FA_hydroxylase  Fatty acid hydroxylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    2.9   0.2    0.0073   1.3e+02      42      94 ..      69     118 ..      62     143 .. 0.59
   2 !   90.3  16.7   7.1e-30   1.3e-25       2     132 ..     176     301 ..     175     302 .. 0.88

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.0073
  FA_hydroxylase  42 laalrahplealllallllllllllgplsalllvlvlaallelliHsglhvsl 94 
                     +a l+a p + +  +++ l+l+++l     +ll++v+  l +++++ + ++++
      EEA18861.1  69 YAYLSAWPRDNIYRQAFSLFLITWLF---GVLLYFVFSSLSYVFVFDKNTFKH 118
                     55555666666666655554443333...344466666666666666633333 PP

  == domain 2  score: 90.3 bits;  conditional E-value: 7.1e-30
  FA_hydroxylase   2 llallledfveYwvHrllHrvkllwrrlHkvHHsseaptalaalrahplealllallll.llllllgplsalllvlvlaallelliHsglhvslg 95 
                      l+ll++df+ Yw+Hr lH+ +l+++rlHk HH+   pt++a++++hp++ + + +++  ++++++ + +a+++++v+ ++++++iH g   ++ 
      EEA18861.1 176 PLFLLFTDFCIYWIHRGLHH-PLIYKRLHKPHHKWIMPTPYASHAFHPVDGWSQSVPYHvFPFIFPLQKWAYVVLFVFINFWTIMIHDG---EYV 266
                     689*************8887.68********************************66651666666699********************...333 PP

  FA_hydroxylase  96 wllerllatpraHrlHHskneegnfgvllslwDrlfg 132
                        + ++++++ H +HH +++ +n+g++++lwDr+ g
      EEA18861.1 267 AN-SPIINGAACHTMHHLYFN-YNYGQYTTLWDRVGG 301
                     33.4569**************.************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (354 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       710  (0.0396006); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2453.14
//
Query:       EEA18862.1  [L=282]
Description: oxidoreductase, short-chain dehydrogenase/reductase family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.9e-42  143.1   0.5    8.7e-42  142.8   0.5    1.1  1  adh_short        short chain dehydrogenase
    3.3e-30  105.4   0.1    4.1e-30  105.1   0.1    1.1  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
      3e-11   43.2   0.0    2.5e-09   36.9   0.0    2.5  2  DUF1776          Fungal family of unknown function (DUF1776)
      1e-09   38.5   0.9    1.4e-09   38.1   0.3    1.4  2  KR               KR domain
    6.4e-06   26.2   0.1    8.8e-06   25.7   0.1    1.2  1  NAD_binding_10   NAD(P)H-binding
    7.4e-05   22.3   0.2    0.00034   20.2   0.2    1.9  1  Epimerase        NAD dependent epimerase/dehydratase family
     0.0018   17.8   0.3     0.0027   17.3   0.3    1.2  1  NmrA             NmrA-like family
     0.0078   16.5   0.1      0.011   15.9   0.1    1.3  1  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma
  ------ inclusion threshold ------
      0.012   16.2   0.0      0.024   15.2   0.0    1.5  1  F420_oxidored    NADP oxidoreductase coenzyme F420-dependent
      0.014   14.8   0.4      0.065   12.6   0.2    2.1  2  GDP_Man_Dehyd    GDP-mannose 4,6 dehydratase
      0.014   15.4   0.0      0.024   14.6   0.0    1.3  1  NAD_Gly3P_dh_N   NAD-dependent glycerol-3-phosphate dehydroge
      0.046   13.6   0.4       0.13   12.1   0.4    1.8  1  Rossmann-like    Rossmann-like domain
       0.11   12.2   0.1       0.15   11.7   0.1    1.3  1  ApbA             Ketopantoate reductase PanE/ApbA
       0.13   12.2   0.1        0.2   11.6   0.1    1.3  1  3HCDH_N          3-hydroxyacyl-CoA dehydrogenase, NAD binding


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  142.8   0.5   6.8e-45   8.7e-42       1     192 [.       4     191 ..       4     194 .. 0.97

  Alignments for each domain:
  == domain 1  score: 142.8 bits;  conditional E-value: 6.8e-45
                 SEEEEESTTS.HHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCSH CS
   adh_short   1 kvvlvtGass.GIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfselse 98 
                 k vlvtG+s+ GIG aia  la++G +v++++r+ +kl  v++ l +    ++++++Dvt++ +v a+ +++ +   +ldvLvnNAG+  ++p+ +++ 
  EEA18862.1   4 KSVLVTGCSAgGIGAAIALLLARKGHHVFATARNTSKLPVVLTTLSN----VTVLSIDVTSMPSVTAAANAVSESGRGLDVLVNNAGLGYVTPILDMDI 98 
                 679****98537*********************************98....9*********************************************** PP

                 HHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHHCT CS
   adh_short  99 eewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakelre 192
                 e+ ++++++Nl g + +++a+ + ++ ++ GrIvn+ S  +  p+++ a+Y+++K a+a ++++l++el+p g++v+av+ G v+T++ +++++
  EEA18862.1  99 ERAQNLYDTNLWGSVRMIQAFKDLLI-ANHGRIVNIISCGAVLPLPWHAPYCSAKIAMANISETLRHELSPFGVSVVAVMVGTVATNFDTNINK 191
                 ********************999988.999**********************************************************999886 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  105.1   0.1   3.2e-33   4.1e-30       3     186 ..      13     193 ..      10     222 .. 0.89

  Alignments for each domain:
  == domain 1  score: 105.1 bits;  conditional E-value: 3.2e-33
                   TTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTT.SEEEE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHHHH CS
  adh_short_C2   3 asgIGraiAkalaeeGaevvltdlneeakkrveelaeelg.aevlecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreefdra 98 
                   a gIG+aiA +la++G +v +t +n ++   +  + + l+  +vl +DVt+  +v+a++++v e+  +lD+lvnnag      +p+l+++ e  ++ 
    EEA18862.1  13 AGGIGAAIALLLARKGHHVFATARNTSK---LPVVLTTLSnVTVLSIDVTSMPSVTAAANAVSESGRGLDVLVNNAGLGYV--TPILDMDIERAQNL 104
                   48*************************9...4444444441669*************************************..************** PP

                   HHHHTHHHHHHHHHHHH.HCTSCCEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTTHH CS
  adh_short_C2  99 ldvnlyslfllakaalp.lmkeggsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikgfd 186
                    d+nl + +++++a++  l++++g+ivn+ s ga   +p ++ y+ aK a+ +++ +l +el p g+ v av  g ++T+  ++i++f+
    EEA18862.1 105 YDTNLWGSVRMIQAFKDlLIANHGRIVNIISCGAVLPLPWHAPYCSAKIAMANISETLRHELSPFGVSVVAVMVGTVATNFDTNINKFN 193
                   *****************888888*************************************************************99975 PP

>> DUF1776  Fungal family of unknown function (DUF1776)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0     0.029        37       6      45 ..       6      45 ..       4      74 .. 0.74
   2 !   36.9   0.0     2e-12   2.5e-09     105     294 ..      90     262 ..      80     264 .. 0.83

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.029
     DUF1776  6 vlvlGsptePltRsialDLerrGFiVfvtvesaeeeklve 45
                vlv G  +  +  +ial L r+G  Vf t+++ ++   v 
  EEA18862.1  6 VLVTGCSAGGIGAAIALLLARKGHHVFATARNTSKLPVVL 45
                7777777778888999*************99988655554 PP

  == domain 2  score: 36.9 bits;  conditional E-value: 2e-12
     DUF1776 105 tgpietiplsswaselnerllspiltlqallplltsrakqkakiivvnpsissslnlpfhapEalvssalsalfevLkrelrphnidvtqikLGnldla 203
                 ++pi  + ++  +++  ++l  ++ ++qa+  ll +   ++ +i+    s  + l lp hap      a+  + e+L++el+p +++v+ + +G++   
  EEA18862.1  90 VTPILDMDIERAQNLYDTNLWGSVRMIQAFKDLLIA---NHGRIV-NIISCGAVLPLPWHAPYCSAKIAMANISETLRHELSPFGVSVVAVMVGTVATN 184
                 6799999****************************8...445544.45688899*****************************************9884 PP

     DUF1776 204 ngsqsnskiasvagsevlsWsesaralygpnyvsilskaisaksir.rgsslreLhnalfdllegsskkrvvyvGkgarlyslvgkllpegl 294
                       +k+   ags           ly+++  +i     ++++ +  g ++ e+ +a+++ + g+  +++vy G  a+++++v+++lp+++
  EEA18862.1 185 -FDTNINKFNLPAGS-----------LYESIKDNIAGW--VTGTAKpVGGPVDEFARAVLEDIVGKGRNGIVYRGDNAAAMGFVASWLPTWI 262
                 .33333333333444...........566555555553..33444459******************************************97 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.1   0.3   1.1e-12   1.4e-09       3     166 ..       6     165 ..       5     182 .. 0.87
   2 ?   -3.5   0.0       6.4   8.2e+03       7      34 ..     220     247 ..     218     252 .. 0.76

  Alignments for each domain:
  == domain 1  score: 38.1 bits;  conditional E-value: 1.1e-12
                 EEEETT.TSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT- CS
          KR   3 ylitGG.lGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklleem 100
                 +l+tG+ +Gg+G ++a  la+kg  h+  ++R+        +++  +  +  +v+v+++Dv++  +v+a+ ++++++++ +   ++ Ag+   +++ +m
  EEA18862.1   6 VLVTGCsAGGIGAAIALLLARKGH-HVFATARNT-------SKLPVVLTTLSNVTVLSIDVTSMPSVTAAANAVSESGRGLDVLVNNAGLGYVTPILDM 96 
                 799**758*************995.899999992.......345666666778********************************************** PP

                 -HHHHHHHHTTTTHHHHHHHHHTTT...S--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHHH CS
          KR 101 taedleqvlapKvkGawnLhelled...esldffvlfSSiagllgsagqanYaaaNaflDalaeyrrsq 166
                 + e+ ++++   + G+  + ++++d    +   +v + S++++l  + +a Y +a   +  + e+ r++
  EEA18862.1  97 DIERAQNLYDTNLWGSVRMIQAFKDlliANHGRIVNIISCGAVLPLPWHAPYCSAKIAMANISETLRHE 165
                 *************************99999999*********************998887777666554 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 6.4
                 TTTSHHHHHHHHHHHHHHS-EEEEE-SS CS
          KR   7 GGlGgLGlelarwlaekgarhlvllsRs 34 
                 G +  +++++ + ++ kg++ +v+ + +
  EEA18862.1 220 GPVDEFARAVLEDIVGKGRNGIVYRGDN 247
                 5567788899999999999999887765 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.7   0.1   6.8e-09   8.8e-06       4      59 ..      14      69 ..      12     131 .. 0.84

  Alignments for each domain:
  == domain 1  score: 25.7 bits;  conditional E-value: 6.8e-09
                    SHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHHCT.TTCEEEE--TT-CCHHHHHHT CS
  NAD_binding_10  4 GkvGrllvkellargghevtalvRnpeklaeleae.eglevvegdvtdvedlaealk 59
                    G++G +++  llar+gh+v a +Rn++kl+ +  + ++++v+++dvt+  ++++a +
      EEA18862.1 14 GGIGAAIAL-LLARKGHHVFATARNTSKLPVVLTTlSNVTVLSIDVTSMPSVTAAAN 69
                    899999886.555558**************8765559***********999999987 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.2   2.7e-07   0.00034       1     173 [.       6     182 ..       6     229 .. 0.77

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 2.7e-07
                 EEEET.TTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC...EEEE--TT-HH...HHHHHHHHH..T-SEEEE--S---H....HHHHHSHHH CS
   Epimerase   1 ilVtG.atGfiGsalvkallekgyevigldrlssasntarledl...elveldltdrs...alerlfkee..qpdavihlAavggv....aassedpad 86 
                 +lVtG  +G iG+a++  l++kg++v + +r++s+ +  +   l   ++  +d+t      a +++++e   + d+ ++ A+ g v    +  +e+++ 
  EEA18862.1   6 VLVTGcSAGGIGAAIALLLARKGHHVFATARNTSKLPVVLTT-LsnvTVLSIDVTSMPsvtAAANAVSESgrGLDVLVNNAGLGYVtpilDMDIERAQN 103
                 69999447************************7777655444.2588999999999884444444555555789*******99998444457999**** PP

                 HHHHHTHHHHHHHHHHHHH...TCTEEEEEEEGGGGTSCSSSSBSTCSTTS----SSHHHHHHHHHHHHHHHHHHHH...T-EEEEEEESEEE CS
   Epimerase  87 fieknlqgtlnlleaarka...gvkrllflsSsevYGkdaeqpkeettltgplkpnspYaaaKlageklveayaaqy...glnaiilrlfnly 173
                 ++++nl g++++++a ++    +  r++++ S+   G         ++   pl+ + pY  aK+a+ ++ e ++++    g++++++++ ++ 
  EEA18862.1 104 LYDTNLWGSVRMIQAFKDLliaNHGRIVNIISC---G--------AVL---PLPWHAPYCSAKIAMANISETLRHELspfGVSVVAVMVGTVA 182
                 *****************7644466699999883...3........234...566688888888888888888877742225666666666655 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.3   2.1e-06    0.0027       1      65 [.       6      71 ..       6      74 .. 0.79

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 2.1e-06
                EEESS.TTSHHHHHHHHHHHHHT-EEEEEES-S-SHHHHHHHHSTTEEEES-TT-HHHHHHHHTT- CS
        NmrA  1 IlviG.aTGrqGksvvrallkaghkvralvRdtkselakslkeaGvelvkgdlddkeslvealkgv 65
                +lv+G ++G +G++++  l+++gh+v+a  R+t++  +     + v++++ d+ +  s+ +a + v
  EEA18862.1  6 VLVTGcSAGGIGAAIALLLARKGHHVFATARNTSKLPVVLTTLSNVTVLSIDVTSMPSVTAAANAV 71
                57887357*************************776655444455777799999888888887655 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.1   8.9e-06     0.011       1     100 [.       6     108 ..       6     129 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 8.9e-06
                      EEEE--..SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHH..HTTS....SEEEE-SSGGGHHHHH CS
  Sacchrp_dh_NADP   1 vliiGa..GsvGqavaellarhfdvdaeitvadrskeklealaakalgvrfeaialdaenyeavLaal..lkeg....dlvvnlsppissldvl 86 
                      vl+ G+  G++G a+a llar++++   +    r+ +kl  ++ ++  ++++  ++d+   ++v+aa+  ++e     d++vn ++  +  ++l
       EEA18862.1   6 VLVTGCsaGGIGAAIALLLARKGHH---VFATARNTSKLPVVLTTL--SNVTVLSIDVTSMPSVTAAAnaVSESgrglDVLVNNAGLGYVTPIL 94 
                      67778777**************986...**************9865..6666666666666665555433666678899999988877888887 PP

                      HHHHHHT-EEEESS CS
  Sacchrp_dh_NADP  87 kaCietgvhyvdts 100
                      ++ ie+  +  dt 
       EEA18862.1  95 DMDIERAQNLYDTN 108
                      77777777766665 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   0.0   1.9e-05     0.024       7      61 ..      13      69 ..      11      72 .. 0.89

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1.9e-05
                   TSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC......-EEECECHHHHHHH CS
  F420_oxidored  7 aGnmgealasgllaagaqpheivvansrnpekaeelaeelg......vkvtavdneeaaee 61
                   aG +g+a+a+ l+++g   h++  a+ rn +k+     +l+      ++vt+++  +aa++
     EEA18862.1 13 AGGIGAAIALLLARKG---HHVF-ATARNTSKLPVVLTTLSnvtvlsIDVTSMPSVTAAAN 69
                   799*************...****.99*******9999999998888888888888888875 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.2     5e-05     0.065       1     125 [.       7     131 ..       7     138 .. 0.77
   2 ?   -2.1   0.0       1.6     2e+03     150     171 ..     145     166 ..     141     175 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 5e-05
                    EEETT.TSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHHHH.....T-SEEEE--S---H.. CS
  GDP_Man_Dehyd   1 LiTGi.aGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkgDltDssslerllaev.....qpdevynLAAqshV.. 88 
                    L+TG  aG iG+ +a lL +kg++v+ + r++s++ +  + +l         +n+++ + D+t   s++ + + v       d  +n A+   V  
     EEA18862.1   7 LVTGCsAGGIGAAIALLLARKGHHVFATARNTSKLPV-VLTTL---------SNVTVLSIDVTSMPSVTAAANAVsesgrGLDVLVNNAGLGYVtp 92 
                    8999758********************9999888653.22232.........46788899999888888777666444555899999999888733 PP

                    ..HHHTTSHHHHHHHHTHHHHHHHHHHHHCT..TTSEEE CS
  GDP_Man_Dehyd  89 ..dvsfekPeytaevnvlGtlrLLeairalglekkvrfy 125
                      d  +e ++  +++n+ G +r+++a ++l ++++ r++
     EEA18862.1  93 ilDMDIERAQNLYDTNLWGSVRMIQAFKDLLIANHGRIV 131
                    335778889999999999999999999988777766665 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.6
                    -SHHHHHHHHHHHHHHHHHHHH CS
  GDP_Man_Dehyd 150 rsPYaaaKlyadwivvnyreay 171
                    + PY  aK++   i +  r++ 
     EEA18862.1 145 HAPYCSAKIAMANISETLRHEL 166
                    679******9999999988875 PP

>> NAD_Gly3P_dh_N  NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.0   1.9e-05     0.024       7      74 ..      13      82 ..       6      97 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 1.9e-05
                    -SHHHHHHHHHHHTTT--EEEE-S-HHHHHHHHHHSSBTTTBTT..----TTEEEES-HHHHHTT--EEE CS
  NAD_Gly3P_dh_N  7 aGswGtalAkvlaenghevrlwvreeelieeineehenvkyLpg..iklpenlvattdlaealkgadiiv 74
                    aG  G a+A +la++gh+v   +r+   + ++ ++  nv+ L    +++p+   a + + e+ +g d++v
      EEA18862.1 13 AGGIGAAIALLLARKGHHVFATARNTSKLPVVLTTLSNVTVLSIdvTSMPSVTAAANAVSESGRGLDVLV 82
                    7999************************************997543566666666777788888888887 PP

>> Rossmann-like  Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.4    0.0001      0.13      16      62 ..      11      56 ..       4      81 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.0001
  Rossmann-like 16 isaGrvGtalgaaleraghvvvgisaisaasreraerrlPdvpvlev 62
                    saG +G+a++  l+r gh+v++ +    +      + l +v+vl++
     EEA18862.1 11 CSAGGIGAAIALLLARKGHHVFATAR-NTSKLPVVLTTLSNVTVLSI 56
                   69*******************99653.33333445555666666555 PP

>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.1   0.00012      0.15       6      33 ..      13      41 ..       6      82 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00012
                -SHHHHHHHHHHHHHTHCEEEE-SCH.HH CS
        ApbA  6 aGaiGsllaakLakagadvtlilrsr.rl 33
                aG+iG  +a  La++g++v   +r+  +l
  EEA18862.1 13 AGGIGAAIALLLARKGHHVFATARNTsKL 41
                7***********************98555 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.1   0.00015       0.2       6      44 ..      12      50 ..       5      76 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00015
                --SCCHHHHHHHHHHTT-EEEEE-S-HHHHHHHHHHHHH CS
     3HCDH_N  6 GaGtmGagiaavfasagleVvlvdiseealekalekiek 44
                 aG +Ga ia ++a++g++V  + +++++l  +l ++++
  EEA18862.1 12 SAGGIGAAIALLLARKGHHVFATARNTSKLPVVLTTLSN 50
                47***********************99999877777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (282 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       451  (0.0251548); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.50u 0.29s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 1897.23
//
Query:       EEA18863.1  [L=584]
Description: transcriptional repressor TupA/RocA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.4e-61  201.8  14.1    1.4e-09   38.4   0.1    7.3  7  WD40          WD domain, G-beta repeat
    8.4e-20   70.9   0.1    0.00027   21.2   0.0    6.6  6  ANAPC4_WD40   Anaphase-promoting complex subunit 4 WD40 domai
    1.2e-17   63.9   9.6    2.1e-17   63.2   9.6    1.4  1  Tup_N         Tup N-terminal
    9.9e-09   34.9   0.0      0.049   13.0   0.0    5.2  6  WD40_like     WD40-like domain
    4.6e-06   25.6   0.1       0.27    9.8   0.0    3.4  3  Nup160        Nucleoporin Nup120/160
    1.7e-05   24.0   0.1       0.57    9.1   0.0    4.5  4  Ge1_WD40      WD40 region of Ge1, enhancer of mRNA-decapping 
    5.4e-05   21.9   0.6    0.00045   18.9   0.2    2.5  2  Cytochrom_D1  Cytochrome D1 heme domain
    0.00081   19.3   0.0      0.059   13.2   0.0    3.1  3  eIF2A         Eukaryotic translation initiation factor eIF2A
  ------ inclusion threshold ------
      0.034   13.5   0.1        7.1    5.9   0.0    2.8  3  Nbas_N        Neuroblastoma-amplified sequence, N terminal
        1.2    9.5   5.0        2.5    8.4   5.0    1.5  1  TPX2          Targeting protein for Xklp2 (TPX2)
        1.5    8.9   5.7        2.1    8.4   5.7    1.1  1  UPF0242       Uncharacterised protein family (UPF0242) N-term


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.2   2.9e-07   0.00048       3      38 .]     271     305 ..     269     305 .. 0.86
   2 !   31.4   0.0   1.4e-10   2.3e-07      12      38 .]     323     353 ..     309     353 .. 0.82
   3 !   38.4   0.1   8.7e-13   1.4e-09       4      38 .]     360     395 ..     357     395 .. 0.94
   4 !   28.4   0.0   1.2e-09     2e-06       3      38 .]     401     436 ..     399     436 .. 0.86
   5 !   26.9   0.0   3.5e-09   5.8e-06       7      37 ..     449     480 ..     444     481 .. 0.91
   6 !   36.9   0.7   2.6e-12   4.2e-09       1      38 []     497     535 ..     497     535 .. 0.95
   7 !   22.3   0.0   1.1e-07   0.00017       4      37 ..     542     576 ..     539     577 .. 0.90

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 2.9e-07
                 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 
                 ++++l  H+s v++++fs+dg+++a+G+ +++  i+d
  EEA18863.1 271 LVHHL-VHDSvVCCVRFSRDGKYVATGC-NRSAQIFD 305
                 67888.596657****************.99998887 PP

  == domain 2  score: 31.4 bits;  conditional E-value: 1.4e-10
                 S....EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  12 s....vtslafspdgawlasGsdDgtvriWd 38 
                 +    ++s++fspdg++la+G +D+ +r+Wd
  EEA18863.1 323 DgdlyIRSVCFSPDGKYLATGAEDKQIRVWD 353
                 245669************************9 PP

  == domain 3  score: 38.4 bits;  conditional E-value: 8.7e-13
                 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                  +++tGH ++++sl+f  +g+++asGs D+tvr+Wd
  EEA18863.1 360 KHVFTGHeQDIYSLDFAGNGRYIASGSGDKTVRLWD 395
                 699****999****************99*******9 PP

  == domain 4  score: 28.4 bits;  conditional E-value: 1.2e-09
                 EEEEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGHssvtslafspdgawlasGsdDgtvriWd 38 
                 +++tl+  ++vt +a spdg+++a+Gs D++vr+Wd
  EEA18863.1 401 LVYTLSIEDGVTTVAMSPDGHYVAAGSLDKSVRVWD 436
                 5666665567*************************9 PP

  == domain 5  score: 26.9 bits;  conditional E-value: 3.5e-09
                 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 
                  +GH +sv+s+af p+g+ l+sGs D+t+++W
  EEA18863.1 449 PDGHkDSVYSVAFAPNGRDLVSGSLDKTIKMW 480
                 57**777************************* PP

  == domain 6  score: 36.9 bits;  conditional E-value: 2.6e-12
                 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 g+c+rt++GH ++v s++  pdg+w++sGs+D+ v +Wd
  EEA18863.1 497 GKCVRTFEGHkDFVLSVCLTPDGHWVMSGSKDRGVQFWD 535
                 79********666*************************9 PP

  == domain 7  score: 22.3 bits;  conditional E-value: 1.1e-07
                 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 
                 +  l GH +sv s+a sp ++++a+Gs D   riW
  EEA18863.1 542 QMMLQGHkNSVISVAPSPTNNLFATGSGDMRARIW 576
                 66799**99999**************99******* PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.1   0.0   0.00046      0.75      26      79 ..     263     318 ..     254     322 .. 0.83
   2 !   21.2   0.0   1.7e-07   0.00027      28      80 ..     311     367 ..     309     369 .. 0.82
   3 !   19.6   0.0     5e-07   0.00082      28      86 ..     361     413 ..     357     416 .. 0.87
   4 !    8.5   0.0    0.0015       2.4      40      77 ..     410     447 ..     406     451 .. 0.91
   5 ?    4.0   0.0     0.038        62      35      66 ..     450     481 ..     446     486 .. 0.88
   6 ?    4.0   0.0     0.037        60      36      82 ..     505     551 ..     497     557 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00046
  ANAPC4_WD40  26 gqrvwtl...eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvk 79 
                   qrv ++   ++  +ds v +++++ dgk  a +++  + +++d+ +g+ v +l+ +
   EEA18863.1 263 VQRVLDVelvHHLVHDSVVCCVRFSRDGKYVATGCNR-SAQIFDVATGQNVATLQDE 318
                  6777777777777999*******************76.679********99998765 PP

  == domain 2  score: 21.2 bits;  conditional E-value: 1.7e-07
  ANAPC4_WD40  28 rvwtl....eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvks 80 
                  +v tl     +++ d  +rs++++pdgk La + +d ++r+ d+ +  + h ++ ++
   EEA18863.1 311 NVATLqdesVDKDGDLYIRSVCFSPDGKYLATGAEDKQIRVWDIATRSIKHVFTGHE 367
                  55555544445678899******************************9999988665 PP

  == domain 3  score: 19.6 bits;  conditional E-value: 5e-07
  ANAPC4_WD40  28 rvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtc 86 
                  +v+t+    +++ + sL +  +g+ +a +  d +vrl d+ +gk+v +ls+++   vt+
   EEA18863.1 361 HVFTG----HEQDIYSLDFAGNGRYIASGSGDKTVRLWDVLEGKLVYTLSIEDG--VTT 413
                  56666....7899************************************99987..554 PP

  == domain 4  score: 8.5 bits;  conditional E-value: 0.0015
  ANAPC4_WD40  40 evrsLaWkpdgklLavaysdgevrlldaesgkvvhsls 77 
                   v+ +a +pdg+  a +  d +vr+ d  +g +v+ l+
   EEA18863.1 410 GVTTVAMSPDGHYVAAGSLDKSVRVWDTTTGYLVERLE 447
                  59999**************************9998875 PP

  == domain 5  score: 4.0 bits;  conditional E-value: 0.038
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdgevrlld 66 
                  d+++ +v s+a+ p+g+ L+ +  d ++++ +
   EEA18863.1 450 DGHKDSVYSVAFAPNGRDLVSGSLDKTIKMWE 481
                  678899*******************9999875 PP

  == domain 6  score: 4.0 bits;  conditional E-value: 0.037
  ANAPC4_WD40  36 kedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksek 82 
                  +++  v s++  pdg+  + + +d  v++ d ++g     l+ ++++
   EEA18863.1 505 GHKDFVLSVCLTPDGHWVMSGSKDRGVQFWDPNTGSAQMMLQGHKNS 551
                  566779999*************************9988888777775 PP

>> Tup_N  Tup N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.2   9.6   1.3e-20   2.1e-17       1      76 [.      15      83 ..      15      84 .. 0.96

  Alignments for each domain:
  == domain 1  score: 63.2 bits;  conditional E-value: 1.3e-20
       Tup_N  1 RlnelLdavkqEfdalsqeasslkaqkdeyelkiqsqiqElqqirqtlyeLeeahrkikqqYEeeiarLkaeLesr 76
                Rl+elL++++qEf++ s+       ++ e+e++++ qiqE+++irq++y+Le+a+ kik +YE+ei+ L++eLesr
  EEA18863.1 15 RLTELLEQLRQEFESQSR-------STGEFEHQLTGQIQEMEMIRQKVYQLEQAQIKIKAEYENEIRVLRHELESR 83
                99************9887.......6789*********************************************98 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0      0.55     9e+02     122     154 ..      43      75 ..      37      90 .. 0.74
   2 ?   -0.8   0.0      0.46   7.5e+02       6      38 ..     284     315 ..     280     320 .. 0.82
   3 !    5.4   0.0    0.0062        10       4      42 ..     329     367 ..     326     370 .. 0.88
   4 !   13.0   0.0     3e-05     0.049       2      38 ..     369     405 ..     368     414 .. 0.89
   5 !    8.5   0.0    0.0007       1.1       4      69 ..     412     481 ..     409     486 .. 0.82
   6 ?    0.5   0.0      0.19     3e+02       5      48 ..     512     555 ..     509     571 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.55
   WD40_like 122 seIkeikiennkiysLsesafivfdlfsqniey 154
                  +I+e++++++k+y L + +  +  ++ ++i++
  EEA18863.1  43 GQIQEMEMIRQKVYQLEQAQIKIKAEYENEIRV 75 
                 57999*********9998887666666666554 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.46
   WD40_like   6 idiskkgslilyGgkddkctvlkleslesvsiv 38 
                 + +s++g++++ G ++  ++++++ +++ v  +
  EEA18863.1 284 VRFSRDGKYVATGCNR-SAQIFDVATGQNVATL 315
                 77999*******9987.5899999999988765 PP

  == domain 3  score: 5.4 bits;  conditional E-value: 0.0062
   WD40_like   4 YsidiskkgslilyGgkddkctvlkleslesvsivesfe 42 
                  s+ +s++g++++ G++d++++v ++ +  ++ ++++ e
  EEA18863.1 329 RSVCFSPDGKYLATGAEDKQIRVWDIATRSIKHVFTGHE 367
                 58889***********************99999988765 PP

  == domain 4  score: 13.0 bits;  conditional E-value: 3e-05
   WD40_like   2 eiYsidiskkgslilyGgkddkctvlkleslesvsiv 38 
                 +iYs+d+  +g +i+ G+ d+++++ ++  +++v+ +
  EEA18863.1 369 DIYSLDFAGNGRYIASGSGDKTVRLWDVLEGKLVYTL 405
                 7***************************999998765 PP

  == domain 5  score: 8.5 bits;  conditional E-value: 0.0007
   WD40_like   4 YsidiskkgslilyGgkddkctvlkleslesvsives...fedSvifvkllddd.lilvvtlDGtillsl 69 
                  ++ +s++g++++ G+ d+ ++v ++ ++ +v  +e+    +dSv  v +  +   ++ ++lD ti +  
  EEA18863.1 412 TTVAMSPDGHYVAAGSLDKSVRVWDTTTGYLVERLENpdgHKDSVYSVAFAPNGrDLVSGSLDKTIKMWE 481
                 57899*************************999876433399*******999983455578999986655 PP

  == domain 6  score: 0.5 bits;  conditional E-value: 0.19
   WD40_like   5 sidiskkgslilyGgkddkctvlkleslesvsivesfedSvifv 48 
                 s+ + ++g+ ++ G+kd  ++  + +++    ++++ ++Svi v
  EEA18863.1 512 SVCLTPDGHWVMSGSKDRGVQFWDPNTGSAQMMLQGHKNSVISV 555
                 67788999*********************************966 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.8   0.0    0.0054       8.8     211     252 ..     316     359 ..     277     369 .. 0.82
   2 !    7.2   0.0    0.0011       1.7     232     259 ..     381     408 ..     370     414 .. 0.87
   3 !    9.8   0.0   0.00017      0.27     222     255 ..     413     445 ..     408     461 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0054
                 --TT-ECEEEEET.......TTTEEEEEETT-EEEEEETTTTEE CS
      Nup160 211 sgasvalsldvavavvei..gqtylfalsrdgkLrvWnlltgkc 252
                 ++ sv+++ d++++ v    + +yl++   d+ +rvW+++t ++
  EEA18863.1 316 QDESVDKDGDLYIRSVCFspDGKYLATGAEDKQIRVWDIATRSI 359
                 56666677777777776677999*****************9876 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0011
                 EEEEEETT-EEEEEETTTTEEEEEEE-- CS
      Nup160 232 ylfalsrdgkLrvWnlltgkclatidll 259
                 y+++ s d+++r+W++l gk+++t ++ 
  EEA18863.1 381 YIASGSGDKTVRLWDVLEGKLVYTLSIE 408
                 7888899****************98775 PP

  == domain 3  score: 9.8 bits;  conditional E-value: 0.00017
                 ET.....TTTEEEEEETT-EEEEEETTTTEEEEE CS
      Nup160 222 avavveigqtylfalsrdgkLrvWnlltgkclat 255
                 +va++  +  y++a s+d+ +rvW+++tg +++ 
  EEA18863.1 413 TVAMSP-DGHYVAAGSLDKSVRVWDTTTGYLVER 445
                 444554.999******************998875 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0     0.098   1.6e+02     184     208 ..     275     299 ..     261     312 .. 0.82
   2 !    9.1   0.0   0.00035      0.57     185     218 ..     323     356 ..     304     368 .. 0.80
   3 !    5.8   0.0    0.0034       5.6     188     215 ..     409     436 ..     380     445 .. 0.82
   4 ?    0.7   0.0      0.12     2e+02     192     218 ..     458     484 ..     448     535 .. 0.49

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.098
    Ge1_WD40 184 ieehsliveaafspdGtalatased 208
                 + ++s + +  fs dG  +at ++ 
  EEA18863.1 275 LVHDSVVCCVRFSRDGKYVATGCNR 299
                 567789999************9974 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.00035
    Ge1_WD40 185 eehsliveaafspdGtalatasedGevkffqvyl 218
                 + +  i +  fspdG  lat +ed +++ + +  
  EEA18863.1 323 DGDLYIRSVCFSPDGKYLATGAEDKQIRVWDIAT 356
                 4455688999********************9975 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.0034
    Ge1_WD40 188 sliveaafspdGtalatasedGevkffq 215
                   +++ a+spdG  +a+ s d  v+ + 
  EEA18863.1 409 DGVTTVAMSPDGHYVAAGSLDKSVRVWD 436
                 458899*******************996 PP

  == domain 4  score: 0.7 bits;  conditional E-value: 0.12
    Ge1_WD40 192 eaafspdGtalatasedGevkffqvyl 218
                 + af+p+G  l   s d ++k++ +  
  EEA18863.1 458 SVAFAPNGRDLVSGSLDKTIKMWELTA 484
                 556666666666666666666665543 PP

>> Cytochrom_D1  Cytochrome D1 heme domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.2   0.1     0.004       6.6      29      74 ..     318     363 ..     288     369 .. 0.60
   2 !   18.9   0.2   2.7e-07   0.00045      12     116 ..     344     447 ..     339     551 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.004
                   EEEE-STTEEE.EEE-TT.SSEEEEEETTSEEEEEESSSSSEEEEEE CS
  Cytochrom_D1  29 avletgyalHi.srvfasdgRyvyvigRDgkvtliDLwakeivaevk 74 
                   + ++  ++l i s+ f++dg+y+ + + D ++ + D+ ++  +++v 
    EEA18863.1 318 ESVDKDGDLYIrSVCFSPDGKYLATGAEDKQIRVWDIATRS-IKHVF 363
                   34566667744366777777777777777777777765443.34444 PP

  == domain 2  score: 18.9 bits;  conditional E-value: 2.7e-07
                   GGGTEEEEEETTT-SEEEEEE-STTEEEEEE-TT.SSEEEEEETTSEEEEEESSSSSEEEEEE-SSEEEEEEE--TTSEEEEEEEETTEEEEEETTT CS
  Cytochrom_D1  12 rdagkvalldgdskeilavletgyalHisrvfasdgRyvyvigRDgkvtliDLwakeivaevkiGlnarsvavSqddryvivgnYlPgqlvildaet 108
                   +++ ++++ d  + +i +v+ ++ +   s  fa +gRy+   + D +v l D+++ + v ++ i      va+S d++yv++g+     + + d+ t
    EEA18863.1 344 AEDKQIRVWDIATRSIKHVFTGHEQDIYSLDFAGNGRYIASGSGDKTVRLWDVLEGKLVYTLSIEDGVTTVAMSPDGHYVAAGSL-DKSVRVWDTTT 439
                   67899**********9999999998899**********************************9999999**************95.46677888877 PP

                   --EEEEEE CS
  Cytochrom_D1 109 Lelvkvis 116
                     lv+ + 
    EEA18863.1 440 GYLVERLE 447
                   77776654 PP

>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.0       0.9   1.5e+03     147     161 ..     282     296 ..     263     312 .. 0.72
   2 !   13.2   0.0   3.6e-05     0.059      53     169 ..     319     434 ..     298     459 .. 0.78
   3 ?    1.6   0.0      0.13   2.1e+02      75     116 ..     521     565 ..     498     581 .. 0.69

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.9
                 -EEEE-TTSSEEEEE CS
       eIF2A 147 tlvewspdgryvlTa 161
                   v +s dg+yv+T 
  EEA18863.1 282 CCVRFSRDGKYVATG 296
                 345799999999985 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 3.6e-05
                 ECCEESSS...EEEEEE-TTSS-EEEEESSSSCEEEEEECS...CEEEEEEEEES--EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE-TT. CS
       eIF2A  53 vvelkkegp..ihdvaWspkskefaviyGkmpakvslfdlk...vkviskleeqkrNtiffspkgklvllaGfgnlaGeleiwdvkkkkkiakaeaan. 145
                 +v  +k+g+  i  v+ sp++k +a   G  ++++ ++d     +k +++ +eq   ++ f  +g++++ +  g+   ++ +wdv + k + ++  ++ 
  EEA18863.1 319 SV--DKDGDlyIRSVCFSPDGKYLA--TGAEDKQIRVWDIAtrsIKHVFTGHEQDIYSLDFAGNGRYIASGS-GDK--TVRLWDVLEGKLVYTLSIEDg 410
                 44..444443488999999999655..899*********954568999999999999999*******98765.554..599*****9999999887762 PP

                 --EEEE-TTSSEEEEEE-TTT-SS CS
       eIF2A 146 atlvewspdgryvlTattaprlrv 169
                  t+v  spdg+yv+  +   ++rv
  EEA18863.1 411 VTTVAMSPDGHYVAAGSLDKSVRV 434
                 57899*******988776655554 PP

  == domain 3  score: 1.6 bits;  conditional E-value: 0.13
                 EEEESSSSCEEEEEECSCEEEEEEEEES--EEEE...-TTSSEEE CS
       eIF2A  75 aviyGkmpakvslfdlkvkviskleeqkrNtiff...spkgklvl 116
                  v+ G  ++ v+++d +     ++ + ++N+++    sp+++l++
  EEA18863.1 521 WVMSGSKDRGVQFWDPNTGSAQMMLQGHKNSVISvapSPTNNLFA 565
                 578888899999999886665555566666543211144444444 PP

>> Nbas_N  Neuroblastoma-amplified sequence, N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.0     0.014        23     229     272 ..     322     368 ..     287     374 .. 0.73
   2 ?    5.9   0.0    0.0043       7.1     228     258 ..     407     437 ..     385     449 .. 0.88
   3 ?   -1.6   0.0      0.82   1.3e+03     226     258 ..     450     482 ..     441     486 .. 0.85

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.014
      Nbas_N 229 kdg...vfkmslspdgtllavihfsgklsiwdipslkqrgeweqeeq 272
                 kdg   +  + +spdg  la+     ++ +wdi +   +  +  +eq
  EEA18863.1 322 KDGdlyIRSVCFSPDGKYLATGAEDKQIRVWDIATRSIKHVFTGHEQ 368
                 44422234567899999999999999999999987777666666666 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0043
      Nbas_N 228 ekdgvfkmslspdgtllavihfsgklsiwdi 258
                  +dgv  +++spdg  +a+  +  ++ +wd 
  EEA18863.1 407 IEDGVTTVAMSPDGHYVAAGSLDKSVRVWDT 437
                 57***************************96 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 0.82
      Nbas_N 226 aeekdgvfkmslspdgtllavihfsgklsiwdi 258
                 +  kd v+ ++++p+g  l    +   + +w++
  EEA18863.1 450 DGHKDSVYSVAFAPNGRDLVSGSLDKTIKMWEL 482
                 56799************9999999999999987 PP

>> TPX2  Targeting protein for Xklp2 (TPX2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   5.0    0.0015       2.5      12      51 ..      36      81 ..      22      84 .. 0.91

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0015
        TPX2 12 eFdkkleekekakeaek......eereakkkeeeeeeikqLRkelv 51
                eF+++l  + +++e+ +      e+++ k k+e e ei+ LR el 
  EEA18863.1 36 EFEHQLTGQIQEMEMIRqkvyqlEQAQIKIKAEYENEIRVLRHELE 81
                8*************99999***9********************986 PP

>> UPF0242  Uncharacterised protein family (UPF0242) N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   5.7    0.0013       2.1      98     169 ..      13      84 ..       9      88 .. 0.92

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0013
     UPF0242  98 eeeLkeeldakeeelerlkeenqqLqekleaiaedfeelkleleeqLaekqellq.eyqetieeqrsvlekrq 169
                 +++L e l++  +e e   +   +++ +l    +++e+ ++++  qL++ q++++ ey+++i  +r +le+r 
  EEA18863.1  13 NNRLTELLEQLRQEFESQSRSTGEFEHQLTGQIQEMEMIRQKVY-QLEQAQIKIKaEYENEIRVLRHELESRG 84 
                 6899*************************************995.799999999659*************995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (584 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       870  (0.0485247); expected 358.6 (0.02)
Passed bias filter:                      674  (0.0375927); expected 358.6 (0.02)
Passed Vit filter:                       112  (0.00624686); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.79u 0.31s 00:00:01.10 Elapsed: 00:00:00.49
# Mc/sec: 3551.88
//
Query:       EEA18864.1  [L=601]
Description: C2H2 transcription factor (Azf1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.3e-14   52.1  37.1    5.7e-05   23.3   1.5    5.8  5  zf-C2H2        Zinc finger, C2H2 type
    1.7e-11   44.0  27.6    1.1e-07   32.0   2.2    5.5  5  zf-H2C2_2      Zinc-finger double domain
    1.3e-05   25.6  33.7     0.0022   18.7   1.3    6.0  5  zf-C2H2_4      C2H2-type zinc finger
  ------ inclusion threshold ------
       0.25   11.5   5.8         14    5.8   0.2    3.7  3  zf-C2H2_aberr  Aberrant zinc-finger
       0.65    9.8  10.4       0.19   11.5   0.5    3.6  3  zf-C2H2_11     zinc-finger C2H2-type


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   1.5       3.4   1.2e+04      13      21 ..      69      77 ..      66      78 .. 0.51
   2 !   14.3   4.3   1.2e-05     0.043       1      23 []     328     352 ..     322     352 .. 0.97
   3 !   20.0   0.6   1.8e-07   0.00064       1      23 []     358     382 ..     358     382 .. 0.98
   4 !   23.3   1.5   1.6e-08   5.7e-05       1      23 []     388     410 ..     388     410 .. 0.98
   5 !   16.3   1.0   2.7e-06    0.0095       1      23 []     416     441 ..     416     441 .. 0.97

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 3.4
                HHHHHHHHH CS
     zf-C2H2 13 ksnLkrHir 21
                + +L +H +
  EEA18864.1 69 QPHLFNHHQ 77
                455555554 PP

  == domain 2  score: 14.3 bits;  conditional E-value: 1.2e-05
                 EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirtH 23 
                 ++C+  +Cgk F++k +L  H+r H
  EEA18864.1 328 HQCTlpGCGKLFTQKTHLDIHMRAH 352
                 799999*****************99 PP

  == domain 3  score: 20.0 bits;  conditional E-value: 1.8e-07
                 EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirtH 23 
                 +kC+   Cg++F++  nL++H r+H
  EEA18864.1 358 FKCNepQCGQRFSQLGNLRTHERRH 382
                 89**********************9 PP

  == domain 4  score: 23.3 bits;  conditional E-value: 1.6e-08
                 EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirtH 23 
                 +kC++Cgk+F +k n ++H+ tH
  EEA18864.1 388 FKCEVCGKCFAQKGNVRAHMFTH 410
                 8*********************9 PP

  == domain 5  score: 16.3 bits;  conditional E-value: 2.7e-06
                 EEET..TTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirt.H 23 
                 y+C    C k F++  nLk+H+++ H
  EEA18864.1 416 YTCQldSCWKQFTQLGNLKSHQNKfH 441
                 99*********************999 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.7       0.2     7e+02      12      25 ..     325     340 ..     321     341 .. 0.62
   2 !   17.0   0.4   1.6e-06    0.0056       2      25 ..     345     370 ..     344     371 .. 0.90
   3 !   32.0   2.2     3e-11   1.1e-07       1      25 [.     374     398 ..     374     399 .. 0.96
   4 !   10.6   0.3   0.00018      0.63       1      25 [.     402     428 ..     402     429 .. 0.85
   5 ?   -3.4   0.3       4.5   1.6e+04       1       9 [.     432     441 ..     432     441 .. 0.66

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.2
   zf-H2C2_2  12 ekpyeCp..lCdkaFk 25 
                 +++++C    C+k F+
  EEA18864.1 325 KRKHQCTlpGCGKLFT 340
                 2347888655888776 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 1.6e-06
   zf-H2C2_2   2 LrrHirkHtgekpyeCp..lCdkaFk 25 
                 L  H+r Htg kp++C    C+ +F+
  EEA18864.1 345 LDIHMRAHTGLKPFKCNepQCGQRFS 370
                 677**************999**9997 PP

  == domain 3  score: 32.0 bits;  conditional E-value: 3e-11
   zf-H2C2_2   1 nLrrHirkHtgekpyeCplCdkaFk 25 
                 nLr H r Htge+p++C++C+k F+
  EEA18864.1 374 NLRTHERRHTGERPFKCEVCGKCFA 398
                 8**********************97 PP

  == domain 4  score: 10.6 bits;  conditional E-value: 0.00018
   zf-H2C2_2   1 nLrrHirkHtgekpyeCp..lCdkaFk 25 
                 n r H+ +H + kpy+C   +C k F+
  EEA18864.1 402 NVRAHMFTHAKSKPYTCQldSCWKQFT 428
                 5789*************9777877776 PP

  == domain 5  score: -3.4 bits;  conditional E-value: 4.5
   zf-H2C2_2   1 nLrrHirk.H 9  
                 nL+ H+ k H
  EEA18864.1 432 NLKSHQNKfH 441
                 7889975436 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   2.8         5   1.8e+04      16      24 .]      67      76 ..      62      76 .. 0.67
   2 !   12.4   1.2   6.6e-05      0.24       1      23 [.     328     352 ..     328     353 .. 0.92
   3 !   14.5   0.5   1.4e-05      0.05       1      23 [.     358     382 ..     358     383 .. 0.88
   4 !   18.7   1.3   6.2e-07    0.0022       1      23 [.     388     410 ..     388     411 .. 0.97
   5 ?    1.7   0.9      0.17   6.1e+02       1      24 []     416     441 ..     416     441 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 5
   zf-C2H2_4 16 Llr.HlkthH 24
                + + Hl +hH
  EEA18864.1 67 YHQpHLFNHH 76
                4344999999 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 6.6e-05
   zf-C2H2_4   1 fkCpi..CgksFsskkaLlrHlkth 23 
                 ++C++  Cgk F+ k++L  H+++h
  EEA18864.1 328 HQCTLpgCGKLFTQKTHLDIHMRAH 352
                 6899999*****99999*******9 PP

  == domain 3  score: 14.5 bits;  conditional E-value: 1.4e-05
   zf-C2H2_4   1 fkCpi..CgksFsskkaLlrHlkth 23 
                 fkC    Cg++Fs   +L++H ++h
  EEA18864.1 358 FKCNEpqCGQRFSQLGNLRTHERRH 382
                 5676666*****************9 PP

  == domain 4  score: 18.7 bits;  conditional E-value: 6.2e-07
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlkth 23 
                 fkC++Cgk F  k +++ H+ th
  EEA18864.1 388 FKCEVCGKCFAQKGNVRAHMFTH 410
                 8*********************9 PP

  == domain 5  score: 1.7 bits;  conditional E-value: 0.17
   zf-C2H2_4   1 fkCpi..CgksFsskkaLlrHlkthH 24 
                 ++C +  C k F+   +L++H ++ H
  EEA18864.1 416 YTCQLdsCWKQFTQLGNLKSHQNKFH 441
                 56777778899*99999****99988 PP

>> zf-C2H2_aberr  Aberrant zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.1    0.0086        31     141     162 ..     328     349 ..     318     355 .. 0.78
   2 ?   -0.1   0.0      0.25   9.1e+02     141     162 ..     358     379 ..     354     389 .. 0.75
   3 ?    5.8   0.2     0.004        14     140     166 ..     415     441 ..     401     450 .. 0.77

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.0086
  zf-C2H2_aberr 141 iyCripGCgkrfkslmaYkYhc 162
                      C +pGCgk f + +    h 
     EEA18864.1 328 HQCTLPGCGKLFTQKTHLDIHM 349
                    57**********9987766665 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.25
  zf-C2H2_aberr 141 iyCripGCgkrfkslmaYkYhc 162
                    + C+ p Cg+rf +l   + h 
     EEA18864.1 358 FKCNEPQCGQRFSQLGNLRTHE 379
                    5688888888888887766664 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.004
  zf-C2H2_aberr 140 liyCripGCgkrfkslmaYkYhckkfl 166
                     + C++  C k+f +l   k h +kf+
     EEA18864.1 415 PYTCQLDSCWKQFTQLGNLKSHQNKFH 441
                    467999999999999999999988885 PP

>> zf-C2H2_11  zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.5      0.08   2.9e+02       5      25 ..     328     350 ..     326     351 .. 0.87
   2 ?    0.9   0.1      0.11     4e+02       9      23 ..     364     378 ..     358     380 .. 0.84
   3 ?   11.5   0.5   5.2e-05      0.19       5      25 ..     388     408 ..     386     410 .. 0.94

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.08
  zf-C2H2_11   5 cqCle..CGlcftSqlsLsRHlf 25 
                 +qC++  CG  ft +  L  H++
  EEA18864.1 328 HQCTLpgCGKLFTQKTHLDIHMR 350
                 7999777******9999999986 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.11
  zf-C2H2_11   9 eCGlcftSqlsLsRH 23 
                 +CG  f+  + L+ H
  EEA18864.1 364 QCGQRFSQLGNLRTH 378
                 7******99999988 PP

  == domain 3  score: 11.5 bits;  conditional E-value: 5.2e-05
  zf-C2H2_11   5 cqCleCGlcftSqlsLsRHlf 25 
                 ++C  CG cf+ ++  + H+f
  EEA18864.1 388 FKCEVCGKCFAQKGNVRAHMF 408
                 69******************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (601 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1181  (0.0658709); expected 358.6 (0.02)
Passed bias filter:                      355  (0.0198003); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.68u 0.28s 00:00:00.96 Elapsed: 00:00:00.51
# Mc/sec: 3545.33
//
Query:       EEA18865.1  [L=317]
Description: mitochondrial folate carrier protein Flx1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.3e-68  224.8   5.0    9.2e-23   80.0   0.0    3.1  3  Mito_carr        Mitochondrial carrier protein
    0.00032   19.9   1.8        1.2    8.3   0.0    3.2  3  Serine_protease  Gammaproteobacterial serine protease


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.0   0.0     1e-26   9.2e-23       7      95 ..      12      99 ..       7     101 .. 0.90
   2 !   70.0   0.3   1.3e-23   1.2e-19       3      92 ..     111     198 ..     109     202 .. 0.92
   3 !   75.9   0.2   1.9e-25   1.7e-21       5      95 ..     218     316 ..     214     317 .] 0.93

  Alignments for each domain:
  == domain 1  score: 80.0 bits;  conditional E-value: 1e-26
                HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHH.HHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCT CS
   Mito_carr  7 kellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykee.GlrglyrGllpnllrvapasalkfvlyetlkrlllk 95
                 e +aG++ag+v+tl  +Pld++Ktrlq+++ + +  +s   l+++++iy++e G+r+lyrGl+pn+++++ +++l+f++y  +k+ + +
  EEA18865.1 12 IETVAGLTAGVVSTLTLHPLDLIKTRLQIDRVTRHRVGS--SLRIISEIYRTEgGIRALYRGLTPNIIGNSTSWSLYFLFYGNIKERIAQ 99
                5789*****************************988766..899******965279*****************************98865 PP

  == domain 2  score: 70.0 bits;  conditional E-value: 1.3e-23
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   3 lsvlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrl 92 
                 ls+ +++la+g+aga+++++t+P++v+Ktr+ + ++ +  ++ +++++   +i+++eG+ g+yrGl+p+l++v+   a +f++ye+lk +
  EEA18865.1 111 LSASEYFLASGAAGALTSILTNPIWVIKTRMLSTGSYTPGAY-QSFMSGATQILRTEGIPGFYRGLVPALFGVS-HGAFQFMAYEKLKSY 198
                 677899*************************99998877755.55****************************9.9***********986 PP

  == domain 3  score: 75.9 bits;  conditional E-value: 1.9e-25
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSS........HHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCT CS
   Mito_carr   5 vlkellaGglagavatlvttPldvvKtrlqtqkksskksksaa........ildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlllk 95 
                  ++ ll++gl++++a+++t+P  v++trlq+q+ ++ +s+++a        +ld++++i+ +eG++g+y+Gl+p+l+rv p++ + f++ye +k  ++k
  EEA18865.1 218 NVELLLISGLSKTFAGCITYPYQVLRTRLQLQAYNADASTKTAlarstyrgVLDAMRQIWAQEGVSGFYKGLGPSLVRVLPSTWVVFLVYENTKAAMYK 316
                 5778999************************99998888877789999999*******************************************99876 PP

>> Serine_protease  Gammaproteobacterial serine protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.5   0.0   0.00045         4       7      62 ..      13      79 ..       8      98 .. 0.72
   2 !    2.9   0.1    0.0055        49      17      68 ..     127     188 ..     112     201 .. 0.76
   3 !    8.3   0.0   0.00013       1.2      19      58 ..     234     272 ..     217     279 .. 0.88

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.00045
  Serine_protease  7 vfktavisfsvsalt.sPfkalLtnlqkdg...svlpsay........sgGlfralYrGflayalags 62
                      +++++++  vs+lt  P+  + t+lq+d      + s++         +G +ralYrG ++  + g+
       EEA18865.1 13 ETVAGLTAGVVSTLTlHPLDLIKTRLQIDRvtrHRVGSSLriiseiyrTEGGIRALYRGLTP-NIIGN 79
                     68899999999998867999999999998521111223335555555645569********9.55444 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.0055
  Serine_protease  17 vsaltsPfkalLtnlqkdgsvlpsay...sgG........lfralYrGflayalagskrrava 68 
                       s+lt+P+ ++ t++   gs +p ay     G         + + YrG ++ al g + +a  
       EEA18865.1 127 TSILTNPIWVIKTRMLSTGSYTPGAYqsfMSGatqilrteGIPGFYRGLVP-ALFGVSHGAFQ 188
                      578999*********999***99998554345688433333457999*999.99999888865 PP

  == domain 3  score: 8.3 bits;  conditional E-value: 0.00013
  Serine_protease  19 altsPfkalLtnlqkdgsvlpsaysgGlfralYrGflaya 58 
                       +t P+++l t+lq +   ++++ +  l r+ YrG+l  a
       EEA18865.1 234 CITYPYQVLRTRLQLQAYNADASTKTALARSTYRGVLD-A 272
                      5799************9999999999*********986.4 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (317 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       332  (0.0185175); expected 358.6 (0.02)
Passed bias filter:                      285  (0.015896); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 2129.46
//
Query:       EEA18866.1  [L=53]
Description: TOM complex component Tom7, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.9e-22   78.1   0.6    3.3e-22   77.9   0.6    1.1  1  Tom7      TOM7 family
  ------ inclusion threshold ------
      0.033   13.9   0.0      0.033   13.9   0.0    1.1  1  DUF4534   Protein of unknown function (DUF4534)


Domain annotation for each model (and alignments):
>> Tom7  TOM7 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.9   0.6   3.6e-26   3.3e-22       1      40 [.       9      48 ..       9      49 .. 0.98

  Alignments for each domain:
  == domain 1  score: 77.9 bits;  conditional E-value: 3.6e-26
        Tom7  1 KeriskvidvsktaiHyGfiPlvlyLGfsksePkpslisL 40
                Keriskvi+vs+ aiHyG++P+++yLG++ sePkp+l++L
  EEA18866.1  9 KERISKVIEVSRIAIHYGYLPFIVYLGYTYSEPKPTLFKL 48
                9**************************************9 PP

>> DUF4534  Protein of unknown function (DUF4534)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   3.7e-06     0.033     119     149 ..      12      41 ..       1      48 [. 0.76

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 3.7e-06
     DUF4534 119 lrlfglisrillhffwlpfvikyayilykdk 149
                 +  ++ +sri++h+  lpf++   y  y ++
  EEA18866.1  12 ISKVIEVSRIAIHYGYLPFIVYLGY-TYSEP 41 
                 566889**************96555.45555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (53 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       300  (0.0167327); expected 358.6 (0.02)
Passed bias filter:                      272  (0.015171); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.37u 0.21s 00:00:00.57 Elapsed: 00:00:00.39
# Mc/sec: 405.55
//
Query:       EEA18867.1  [L=351]
Description: splicing factor 3b subunit 4 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.4e-33  114.5   0.0    1.7e-15   56.5   0.0    2.2  2  RRM_1           RNA recognition motif. (a.k.a. RRM, RBD, or R
     0.0024   17.5   0.1      0.073   12.7   0.0    2.2  2  RRM_5           RNA recognition motif. (a.k.a. RRM, RBD, or R
     0.0086   16.2   0.0      0.085   13.0   0.0    2.2  2  RRM_7           RNA recognition motif
  ------ inclusion threshold ------
       0.01   15.5   0.5        1.1    9.0   0.1    2.5  2  OB_RNB          Ribonuclease B OB domain
      0.023   14.8   0.0        4.3    7.5   0.0    2.3  2  Cas_Cas2CT1978  CRISPR-associated protein (Cas_Cas2CT1978)


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.5   0.0   4.9e-19   1.7e-15       1      70 []      15      85 ..      15      85 .. 0.98
   2 !   56.1   0.0   6.7e-19   2.4e-15       1      69 [.     103     172 ..     103     173 .. 0.96

  Alignments for each domain:
  == domain 1  score: 56.5 bits;  conditional E-value: 4.9e-19
                EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEEE CS
       RRM_1  1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrelk 70
                +++gnL + vt++ + el+ + G+i+++ l++d  t++++g++fVeF s+edAe A + +n   l g++++
  EEA18867.1 15 VYIGNLDERVTDSLVWELMLQAGRIVNVHLPKDrVTQTHQGYGFVEFISEEDAEYAARIMNQVRLYGKPIR 85
                8**************************************************************99999986 PP

  == domain 2  score: 56.1 bits;  conditional E-value: 6.7e-19
                 EEEESETTTSSHHHHHHHHHTTSCEEEE.EEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksi.klvrdetgkskgfafVeFeskedAekAlealngkklggrel 69 
                 lfVgnL p v+e+ L++ Fs fG   s+ k+ rd  + skg++fV F++ ++ ++A+++++g+ l+++e+
  EEA18867.1 103 LFVGNLDPMVSEQVLYDTFSRFGTLLSLpKIARDDANLSKGYGFVSFADFDASDAAIANMHGQYLMNKEV 172
                 8************************888689999*********************************997 PP

>> RRM_5  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   0.0     2e-05     0.073      38     104 ..      23      97 ..       4     110 .. 0.69
   2 ?    2.7   0.0     0.025        88      63      98 ..     141     176 ..      97     185 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2e-05
       RRM_5  38 kvnldklFnlfclYgnverv.....kflktkketalvqmgdasaveravqHLnnaklfgkrlevalS...Kqqav 104
                 +v+ + ++ l+ + g +  v     ++ +t +++ +v+  ++ ++e a   +n ++l+gk+++v      Kq++v
  EEA18867.1  23 RVTDSLVWELMLQAGRIVNVhlpkdRVTQTHQGYGFVEFISEEDAEYAARIMNQVRLYGKPIRVNKAsadKQKTV 97 
                 45555666666666655555111113567899****************************998853212266665 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.025
       RRM_5  63 kketalvqmgdasaveravqHLnnaklfgkrleval 98 
                  k++ +v  +d  a + a+  + ++ l +k++ v+ 
  EEA18867.1 141 SKGYGFVSFADFDASDAAIANMHGQYLMNKEVSVQY 176
                 478999*********************999888765 PP

>> RRM_7  RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0      0.17   6.3e+02       4      57 ..      15      61 ..      13      86 .. 0.66
   2 !   13.0   0.0   2.4e-05     0.085       4      62 ..     103     154 ..     100     178 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.17
       RRM_7  4 vFvGGlPiDiteeelkatfkefgk.vlvdwPkkaeskkkaaenskaakgyvflvf 57
                v++G l   +t++ +++ + + g+ v v  Pk   +        ++++gy f+ f
  EEA18867.1 15 VYIGNLDERVTDSLVWELMLQAGRiVNVHLPKDRVT--------QTHQGYGFVEF 61
                777777777888888777777776234666665322........22345555544 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 2.4e-05
       RRM_7   4 vFvGGlPiDiteeelkatfkefgkvlvdwPkkaeskkkaaenskaakgyvflvfedeks 62 
                 +FvG l + ++e+ l++tf++fg++ +  Pk a+ +++ +      kgy f+ f d ++
  EEA18867.1 103 LFVGNLDPMVSEQVLYDTFSRFGTL-LSLPKIARDDANLS------KGYGFVSFADFDA 154
                 7**********************87.58999999877754......6888888877555 PP

>> OB_RNB  Ribonuclease B OB domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.0    0.0099        36       2      15 ..      48      61 ..      48      70 .. 0.80
   2 ?    9.0   0.1    0.0003       1.1       7      53 ..     141     188 ..     140     192 .. 0.82

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.0099
                EEEE-SSS-EEEEE CS
      OB_RNB  2 tvrahkkGFGFlip 15
                +v+ + +G+GF++ 
  EEA18867.1 48 RVTQTHQGYGFVEF 61
                588899******85 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.0003
                 SSS-EEEEECT..TEEEEE-HHHHTTS-TT-EEEEEEEE.SSSEEEEEE CS
      OB_RNB   7 kkGFGFlipde.gkeDifippeqmkkamhGDrVlvritk.gdrrgrreg 53 
                 +kG+GF++  + + +D  i + + ++ m++  V v+    +d +g+r g
  EEA18867.1 141 SKGYGFVSFADfDASDAAIANMHGQYLMNK-EVSVQYAYkKDGKGERHG 188
                 59*******999***************998.677777765666666655 PP

>> Cas_Cas2CT1978  CRISPR-associated protein (Cas_Cas2CT1978)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   0.0    0.0012       4.3      24      48 ..      11      36 ..       5      62 .. 0.70
   2 ?    5.0   0.0    0.0071        25      21      44 ..      96     119 ..      93     149 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0012
                    EETTEEEEEE-HHHHHHH.HHHHHHH CS
  Cas_Cas2CT1978 24 vragVyvgrvsarVrekl.werveek 48
                     +a Vy+g++ +rV ++l we + ++
      EEA18867.1 11 KEATVYIGNLDERVTDSLvWELMLQA 36
                    5799***********98626555444 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.0071
                     SEEEETTEEEEEE-HHHHHHHHHH CS
  Cas_Cas2CT1978  21 llEvragVyvgrvsarVreklwer 44 
                      +Ev a ++vg++  +V e+++  
      EEA18867.1  96 TVEVGAELFVGNLDPMVSEQVLYD 119
                     68*****************99865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (351 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       393  (0.0219198); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2334.38
//
Query:       EEA18868.1  [L=125]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.6e-47  158.5   0.0    5.2e-47  158.3   0.0    1.0  1  DUF2015   Fungal protein of unknown function (DUF2015)


Domain annotation for each model (and alignments):
>> DUF2015  Fungal protein of unknown function (DUF2015)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  158.3   0.0   2.9e-51   5.2e-47       2     112 .]       9     120 ..       8     120 .. 0.98

  Alignments for each domain:
  == domain 1  score: 158.3 bits;  conditional E-value: 2.9e-51
     DUF2015   2 lllvlvvatllyltrkkllpllpea.eeylysrlpssFeedieaGlsssnFdlseNiesgdsRaGLdeaakeeikkimkkrrvkFdeARliyteerlkk 99 
                 +++v+vv+t+lyltr+++lpl++++  +y+y rlp++F++dieaG++ss+Fdl++N+ +gdsR+GLd++ak+ei++imk+r+v+FdeAR++yte+r++k
  EEA18868.1   9 TFMVVVVGTVLYLTRTRWLPLVEDHvPDYVYDRLPTTFSGDIEAGFTSSEFDLTNNVLEGDSRSGLDNKAKREIRRIMKRRGVDFDEARRLYTEQRFAK 107
                 799********************99899*********************************************************************** PP

     DUF2015 100 ngigpdGrPlDpk 112
                 n+igpdGrP+Dpk
  EEA18868.1 108 NDIGPDGRPRDPK 120
                 ************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (125 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       663  (0.0369792); expected 358.6 (0.02)
Passed bias filter:                      622  (0.0346924); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.28s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 852.72
//
Query:       EEA18869.1  [L=155]
Description: 60S ribosomal protein L28 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.9e-34  116.5   0.8    1.2e-33  116.2   0.8    1.1  1  Ribosomal_L28e  Ribosomal L28e protein family


Domain annotation for each model (and alignments):
>> Ribosomal_L28e  Ribosomal L28e protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.2   0.8   6.9e-38   1.2e-33       1     115 []      12     131 ..      12     131 .. 0.97

  Alignments for each domain:
  == domain 1  score: 116.2 bits;  conditional E-value: 6.9e-38
  Ribosomal_L28e   1 LiWelvrnnnsFlvktrtsnkqtFsrepyNltglhsrkysglanskavtVr.eekkgvvlvtkkkerahkpakawekvkls..knsrkalkqiak 92 
                     L+W+++rn+n+Flv++++  + +Fsr+p+N +++hsrky+g+an+ka++++ +e++gvvl+ k++++ ++pak++ +v++   +++rk++k++a+
      EEA18869.1  12 LVWQITRNQNAFLVQRHNAGGVRFSRDPLNPVNVHSRKYAGYANDKALGLQaSENGGVVLIAKNASNTQNPAKSIRTVTYGpkTSNRKIYKSVAS 106
                     89**************9999*******************************8779***************************9999********* PP

  Ribosomal_L28e  93 ll..kkyrpdlrkaalaRlskitqs 115
                     ++  ++yr dlr+aa+aR+s++++s
      EEA18869.1 107 STakNGYRADLREAAVARVSALRRS 131
                     ***9999***************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (155 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       531  (0.0296168); expected 358.6 (0.02)
Passed bias filter:                      280  (0.0156172); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.27s 00:00:00.66 Elapsed: 00:00:00.41
# Mc/sec: 1142.68
//
Query:       EEA18870.1  [L=331]
Description: malate dehydrogenase, NAD-dependent [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.9e-44  150.6   0.0    4.2e-44  150.1   0.0    1.2  1  Ldh_1_N        lactate/malate dehydrogenase, NAD binding doma
      1e-43  149.2   0.0    1.4e-43  148.7   0.0    1.2  1  Ldh_1_C        lactate/malate dehydrogenase, alpha/beta C-ter
    0.00028   20.0   0.0    0.00044   19.4   0.0    1.4  1  3Beta_HSD      3-beta hydroxysteroid dehydrogenase/isomerase 
  ------ inclusion threshold ------
       0.02   14.4   0.1        1.9    8.0   0.1    2.3  2  Glyco_hydro_4  Family 4 glycosyl hydrolase
      0.063   12.6   0.1       0.67    9.3   0.1    2.2  1  THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase,


Domain annotation for each model (and alignments):
>> Ldh_1_N  lactate/malate dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  150.1   0.0   1.2e-47   4.2e-44       2     141 .]       3     146 ..       2     146 .. 0.98

  Alignments for each domain:
  == domain 1  score: 150.1 bits;  conditional E-value: 1.2e-47
                 EEEEETTTSHHHHHHHHHHHHTTSSSEEEEE-SSHHHHHHHHHHHHHCHCCSTS-EEEEE..SSGGGGTTESEEEE--S-SS-TTTTHHHHHHHHHHHH CS
     Ldh_1_N   2 kvavvGaaGgiGqslalllankkladelaLlDiakekleGvaldlshistflsvkvkvse..keeealkdadvvvitagvprkpGetRddLlkvNakIv 98 
                 k +v+Ga+GgiGq+l+ll ++++l+delaL+D++  +++Gva+dlshis ++++ ++ ++  + ++al++ad+vvi+ag+prkpG+tRddL+k+Na+Iv
  EEA18870.1   3 KAVVLGASGGIGQPLSLLFKASPLVDELALYDVV--NTPGVAADLSHISSPAKITGYLPAddGLKKALTGADIVVIPAGIPRKPGMTRDDLFKINAGIV 99 
                 789*******************************..9********************9987789*********************************** PP

                 HHHHHHHHHHTTTSEEEE-SSSHH....HHHHHHHHHHTS-GGGEEE CS
     Ldh_1_N  99 keiveaiakvapnaivlvvsNPvd....iltevlkkasglpkkrvig 141
                 +++v+ ia+++p+a vl++sNPv+    i++evlk a+ +++kr++g
  EEA18870.1 100 QTLVKGIAEFSPEAYVLIISNPVNstvpIAAEVLKAAGVFNPKRLFG 146
                 *********************************************98 PP

>> Ldh_1_C  lactate/malate dehydrogenase, alpha/beta C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  148.7   0.0     4e-47   1.4e-43       1     167 []     148     324 ..     148     324 .. 0.92

  Alignments for each domain:
  == domain 1  score: 148.7 bits;  conditional E-value: 4e-47
                 THHHHHHHHHHHHHHHTS.-GGGEE--EEBSSSTETTEEHHHHHTTSTTSTHHHHHHHHHHHHHHHHHHHHHHTTSSSS-HHHHHHHHHHHHHHHTTHT CS
     Ldh_1_C   1 TtLDivRaktflaekagv.tprsvkvtViGgHsgvtiipllsqvkellklsekqleeliervqnggdevvkakkGagsatlsmAvAgakfveallrdtk 98 
                 TtLD+vRa+tf+ e +g  +p++  ++V+GgHsg ti+pl+sq+k + ++  +++++l++rvq+ggdevvkak+GagsatlsmA+Ag +f+e++++++k
  EEA18870.1 148 TTLDVVRAETFVQEWSGQkNPSETTIPVVGGHSGDTIVPLFSQAKPAFQIPADKYDALVNRVQFGGDEVVKAKDGAGSATLSMAYAGFRFAESVIKAVK 246
                 9*************999889******************************************************************************6 PP

                 EEEEEEEEEESCCCECCS..........SEEEEEEEEEEETTEEEEE-----.--HHHHHHHHHHHHHHHHHHHHHHCCH CS
     Ldh_1_C  99 eilsagvyldgevglkdq..........eieyfsvPvvlgknGvekvleilk.lndfeeekleksvkeLkkeiekglefv 167
                 ++  +g+++++ v l+            ++++fsvP+ lg++Gv++ +++l+  ++ e++ le ++k Lk +iekg++fv
  EEA18870.1 247 GE--KGIVEPSFVYLPGVpggeaiqkatGVDFFSVPIELGTDGVSNTINVLEnTTETEKKLLEVAIKGLKTNIEKGVDFV 324
                 66..666666666555555556668899*******************99988799999999***************9985 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.0   1.2e-07   0.00044       1      93 [.       5      96 ..       5     142 .. 0.90

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 1.2e-07
   3Beta_HSD  1 vvtGgaGFlGralvkeLvrlee.lkevrvlDlrespelleelskvnvkkviegDvtdkdkleealegvdvvihlaslvdvagkltedeimkvnv 93
                vv+G++G +G+ l + L+++ + + e+  +D+++ p +  +ls++     i+g +   d l++al g+d+v+  a++    g++++d + k+n 
  EEA18870.1  5 VVLGASGGIGQPL-SLLFKASPlVDELALYDVVNTPGVAADLSHISSPAKITGYLPADDGLKKALTGADIVVIPAGIPRKPGMTRDD-LFKINA 96
                89*********98.6788888879**********************999*****************************999977766.778775 PP

>> Glyco_hydro_4  Family 4 glycosyl hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0    0.0026       9.4      58     104 ..      55     101 ..      15     104 .. 0.75
   2 ?    8.0   0.1   0.00053       1.9     124     149 ..      99     124 ..      94     142 .. 0.83

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0026
                    TCEEEEESSHHHHHTT-SEEEE---TTHHHHHHHHHHCCHTTTTT-C CS
  Glyco_hydro_4  58 dlkieattdrkealkdadfVitairvGlekareidekiplryGieqt 104
                       + a + +k+al+ ad+V++ + +  ++ +  d     + Gi+qt
     EEA18870.1  55 TGYLPADDGLKKALTGADIVVIPAGIPRKPGMTRDDLFKINAGIVQT 101
                    4555666779*************999999999999999999999986 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.00053
                    HHHHHHHHHHH-TTSEEEE-SSSHHH CS
  Glyco_hydro_4 124 lleIakdieelcPdawvlnytNPaav 149
                    +  ++k i e++P+a+vl  +NP+  
     EEA18870.1  99 VQTLVKGIAEFSPEAYVLIISNPVNS 124
                    5567999****************975 PP

>> THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.1   0.00019      0.67      38      91 ..       3      82 ..       2     126 .. 0.66

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00019
                   EEEEE---TTTHHHHHHHHHC.............T.............T-EEEEE-TTSCCHHHHHCCSSEEEE-SS-TT CS
  THF_DHG_CYH_C 38 kvvvvGrsnivgkplallLle.............k.............natVtvchsktkdlaeitreadivvvavGkpe 91
                   k+vv+G+s  +g+pl+ll+++             +              a +t    + + l++ +  adivv+ +G p+
     EEA18870.1  3 KAVVLGASGGIGQPLSLLFKAsplvdelalydvvNtpgvaadlshissPAKITGYLPADDGLKKALTGADIVVIPAGIPR 82
                   699****************9955555444444440444434444444456666666666778888888888888888654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (331 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       416  (0.0232026); expected 358.6 (0.02)
Passed bias filter:                      399  (0.0222544); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.47u 0.21s 00:00:00.68 Elapsed: 00:00:00.37
# Mc/sec: 2673.54
//
Query:       EEA18871.1  [L=330]
Description: malate dehydrogenase, NAD-dependent [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.9e-44  150.6   0.0    4.2e-44  150.1   0.0    1.2  1  Ldh_1_N        lactate/malate dehydrogenase, NAD binding doma
      1e-43  149.2   0.0    1.4e-43  148.7   0.0    1.2  1  Ldh_1_C        lactate/malate dehydrogenase, alpha/beta C-ter
    0.00028   20.0   0.0    0.00043   19.4   0.0    1.4  1  3Beta_HSD      3-beta hydroxysteroid dehydrogenase/isomerase 
  ------ inclusion threshold ------
       0.02   14.5   0.1        1.9    8.0   0.1    2.3  2  Glyco_hydro_4  Family 4 glycosyl hydrolase
      0.063   12.6   0.1       0.67    9.3   0.1    2.2  1  THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase,


Domain annotation for each model (and alignments):
>> Ldh_1_N  lactate/malate dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  150.1   0.0   1.2e-47   4.2e-44       2     141 .]       3     146 ..       2     146 .. 0.98

  Alignments for each domain:
  == domain 1  score: 150.1 bits;  conditional E-value: 1.2e-47
                 EEEEETTTSHHHHHHHHHHHHTTSSSEEEEE-SSHHHHHHHHHHHHHCHCCSTS-EEEEE..SSGGGGTTESEEEE--S-SS-TTTTHHHHHHHHHHHH CS
     Ldh_1_N   2 kvavvGaaGgiGqslalllankkladelaLlDiakekleGvaldlshistflsvkvkvse..keeealkdadvvvitagvprkpGetRddLlkvNakIv 98 
                 k +v+Ga+GgiGq+l+ll ++++l+delaL+D++  +++Gva+dlshis ++++ ++ ++  + ++al++ad+vvi+ag+prkpG+tRddL+k+Na+Iv
  EEA18871.1   3 KAVVLGASGGIGQPLSLLFKASPLVDELALYDVV--NTPGVAADLSHISSPAKITGYLPAddGLKKALTGADIVVIPAGIPRKPGMTRDDLFKINAGIV 99 
                 789*******************************..9********************9987789*********************************** PP

                 HHHHHHHHHHTTTSEEEE-SSSHH....HHHHHHHHHHTS-GGGEEE CS
     Ldh_1_N  99 keiveaiakvapnaivlvvsNPvd....iltevlkkasglpkkrvig 141
                 +++v+ ia+++p+a vl++sNPv+    i++evlk a+ +++kr++g
  EEA18871.1 100 QTLVKGIAEFSPEAYVLIISNPVNstvpIAAEVLKAAGVFNPKRLFG 146
                 *********************************************98 PP

>> Ldh_1_C  lactate/malate dehydrogenase, alpha/beta C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  148.7   0.0   3.9e-47   1.4e-43       1     167 []     148     324 ..     148     324 .. 0.92

  Alignments for each domain:
  == domain 1  score: 148.7 bits;  conditional E-value: 3.9e-47
                 THHHHHHHHHHHHHHHTS.-GGGEE--EEBSSSTETTEEHHHHHTTSTTSTHHHHHHHHHHHHHHHHHHHHHHTTSSSS-HHHHHHHHHHHHHHHTTHT CS
     Ldh_1_C   1 TtLDivRaktflaekagv.tprsvkvtViGgHsgvtiipllsqvkellklsekqleeliervqnggdevvkakkGagsatlsmAvAgakfveallrdtk 98 
                 TtLD+vRa+tf+ e +g  +p++  ++V+GgHsg ti+pl+sq+k + ++  +++++l++rvq+ggdevvkak+GagsatlsmA+Ag +f+e++++++k
  EEA18871.1 148 TTLDVVRAETFVQEWSGQkNPSETTIPVVGGHSGDTIVPLFSQAKPAFQIPADKYDALVNRVQFGGDEVVKAKDGAGSATLSMAYAGFRFAESVIKAVK 246
                 9*************999889******************************************************************************6 PP

                 EEEEEEEEEESCCCECCS..........SEEEEEEEEEEETTEEEEE-----.--HHHHHHHHHHHHHHHHHHHHHHCCH CS
     Ldh_1_C  99 eilsagvyldgevglkdq..........eieyfsvPvvlgknGvekvleilk.lndfeeekleksvkeLkkeiekglefv 167
                 ++  +g+++++ v l+            ++++fsvP+ lg++Gv++ +++l+  ++ e++ le ++k Lk +iekg++fv
  EEA18871.1 247 GE--KGIVEPSFVYLPGVpggeaiqkatGVDFFSVPIELGTDGVSNTINVLEnTTETEKKLLEVAIKGLKTNIEKGVDFV 324
                 66..666666666555555556668899*******************99988799999999***************9985 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.0   1.2e-07   0.00043       1      93 [.       5      96 ..       5     142 .. 0.90

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 1.2e-07
   3Beta_HSD  1 vvtGgaGFlGralvkeLvrlee.lkevrvlDlrespelleelskvnvkkviegDvtdkdkleealegvdvvihlaslvdvagkltedeimkvnv 93
                vv+G++G +G+ l + L+++ + + e+  +D+++ p +  +ls++     i+g +   d l++al g+d+v+  a++    g++++d + k+n 
  EEA18871.1  5 VVLGASGGIGQPL-SLLFKASPlVDELALYDVVNTPGVAADLSHISSPAKITGYLPADDGLKKALTGADIVVIPAGIPRKPGMTRDD-LFKINA 96
                89*********98.6788888879**********************999*****************************999977766.778775 PP

>> Glyco_hydro_4  Family 4 glycosyl hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0    0.0026       9.3      58     104 ..      55     101 ..      15     104 .. 0.75
   2 ?    8.0   0.1   0.00053       1.9     124     149 ..      99     124 ..      94     142 .. 0.83

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0026
                    TCEEEEESSHHHHHTT-SEEEE---TTHHHHHHHHHHCCHTTTTT-C CS
  Glyco_hydro_4  58 dlkieattdrkealkdadfVitairvGlekareidekiplryGieqt 104
                       + a + +k+al+ ad+V++ + +  ++ +  d     + Gi+qt
     EEA18871.1  55 TGYLPADDGLKKALTGADIVVIPAGIPRKPGMTRDDLFKINAGIVQT 101
                    4555666779*************999999999999999999999986 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.00053
                    HHHHHHHHHHH-TTSEEEE-SSSHHH CS
  Glyco_hydro_4 124 lleIakdieelcPdawvlnytNPaav 149
                    +  ++k i e++P+a+vl  +NP+  
     EEA18871.1  99 VQTLVKGIAEFSPEAYVLIISNPVNS 124
                    5567999****************975 PP

>> THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.1   0.00019      0.67      38      91 ..       3      82 ..       2     126 .. 0.66

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00019
                   EEEEE---TTTHHHHHHHHHC.............T.............T-EEEEE-TTSCCHHHHHCCSSEEEE-SS-TT CS
  THF_DHG_CYH_C 38 kvvvvGrsnivgkplallLle.............k.............natVtvchsktkdlaeitreadivvvavGkpe 91
                   k+vv+G+s  +g+pl+ll+++             +              a +t    + + l++ +  adivv+ +G p+
     EEA18871.1  3 KAVVLGASGGIGQPLSLLFKAsplvdelalydvvNtpgvaadlshissPAKITGYLPADDGLKKALTGADIVVIPAGIPR 82
                   699****************9955555444444440444434444444456666666666778888888888888888654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (330 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       415  (0.0231469); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.41
# Mc/sec: 2412.88
//
Query:       EEA18872.1  [L=330]
Description: malate dehydrogenase, NAD-dependent [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.9e-44  150.6   0.0    4.2e-44  150.1   0.0    1.2  1  Ldh_1_N        lactate/malate dehydrogenase, NAD binding doma
      1e-43  149.2   0.0    1.4e-43  148.7   0.0    1.2  1  Ldh_1_C        lactate/malate dehydrogenase, alpha/beta C-ter
    0.00028   20.0   0.0    0.00043   19.4   0.0    1.4  1  3Beta_HSD      3-beta hydroxysteroid dehydrogenase/isomerase 
  ------ inclusion threshold ------
       0.02   14.5   0.1        1.9    8.0   0.1    2.3  2  Glyco_hydro_4  Family 4 glycosyl hydrolase
      0.063   12.6   0.1       0.67    9.3   0.1    2.2  1  THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase,


Domain annotation for each model (and alignments):
>> Ldh_1_N  lactate/malate dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  150.1   0.0   1.2e-47   4.2e-44       2     141 .]       3     146 ..       2     146 .. 0.98

  Alignments for each domain:
  == domain 1  score: 150.1 bits;  conditional E-value: 1.2e-47
                 EEEEETTTSHHHHHHHHHHHHTTSSSEEEEE-SSHHHHHHHHHHHHHCHCCSTS-EEEEE..SSGGGGTTESEEEE--S-SS-TTTTHHHHHHHHHHHH CS
     Ldh_1_N   2 kvavvGaaGgiGqslalllankkladelaLlDiakekleGvaldlshistflsvkvkvse..keeealkdadvvvitagvprkpGetRddLlkvNakIv 98 
                 k +v+Ga+GgiGq+l+ll ++++l+delaL+D++  +++Gva+dlshis ++++ ++ ++  + ++al++ad+vvi+ag+prkpG+tRddL+k+Na+Iv
  EEA18872.1   3 KAVVLGASGGIGQPLSLLFKASPLVDELALYDVV--NTPGVAADLSHISSPAKITGYLPAddGLKKALTGADIVVIPAGIPRKPGMTRDDLFKINAGIV 99 
                 789*******************************..9********************9987789*********************************** PP

                 HHHHHHHHHHTTTSEEEE-SSSHH....HHHHHHHHHHTS-GGGEEE CS
     Ldh_1_N  99 keiveaiakvapnaivlvvsNPvd....iltevlkkasglpkkrvig 141
                 +++v+ ia+++p+a vl++sNPv+    i++evlk a+ +++kr++g
  EEA18872.1 100 QTLVKGIAEFSPEAYVLIISNPVNstvpIAAEVLKAAGVFNPKRLFG 146
                 *********************************************98 PP

>> Ldh_1_C  lactate/malate dehydrogenase, alpha/beta C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  148.7   0.0   3.9e-47   1.4e-43       1     167 []     148     324 ..     148     324 .. 0.92

  Alignments for each domain:
  == domain 1  score: 148.7 bits;  conditional E-value: 3.9e-47
                 THHHHHHHHHHHHHHHTS.-GGGEE--EEBSSSTETTEEHHHHHTTSTTSTHHHHHHHHHHHHHHHHHHHHHHTTSSSS-HHHHHHHHHHHHHHHTTHT CS
     Ldh_1_C   1 TtLDivRaktflaekagv.tprsvkvtViGgHsgvtiipllsqvkellklsekqleeliervqnggdevvkakkGagsatlsmAvAgakfveallrdtk 98 
                 TtLD+vRa+tf+ e +g  +p++  ++V+GgHsg ti+pl+sq+k + ++  +++++l++rvq+ggdevvkak+GagsatlsmA+Ag +f+e++++++k
  EEA18872.1 148 TTLDVVRAETFVQEWSGQkNPSETTIPVVGGHSGDTIVPLFSQAKPAFQIPADKYDALVNRVQFGGDEVVKAKDGAGSATLSMAYAGFRFAESVIKAVK 246
                 9*************999889******************************************************************************6 PP

                 EEEEEEEEEESCCCECCS..........SEEEEEEEEEEETTEEEEE-----.--HHHHHHHHHHHHHHHHHHHHHHCCH CS
     Ldh_1_C  99 eilsagvyldgevglkdq..........eieyfsvPvvlgknGvekvleilk.lndfeeekleksvkeLkkeiekglefv 167
                 ++  +g+++++ v l+            ++++fsvP+ lg++Gv++ +++l+  ++ e++ le ++k Lk +iekg++fv
  EEA18872.1 247 GE--KGIVEPSFVYLPGVpggeaiqkatGVDFFSVPIELGTDGVSNTINVLEnTTETEKKLLEVAIKGLKTNIEKGVDFV 324
                 66..666666666555555556668899*******************99988799999999***************9985 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.0   1.2e-07   0.00043       1      93 [.       5      96 ..       5     142 .. 0.90

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 1.2e-07
   3Beta_HSD  1 vvtGgaGFlGralvkeLvrlee.lkevrvlDlrespelleelskvnvkkviegDvtdkdkleealegvdvvihlaslvdvagkltedeimkvnv 93
                vv+G++G +G+ l + L+++ + + e+  +D+++ p +  +ls++     i+g +   d l++al g+d+v+  a++    g++++d + k+n 
  EEA18872.1  5 VVLGASGGIGQPL-SLLFKASPlVDELALYDVVNTPGVAADLSHISSPAKITGYLPADDGLKKALTGADIVVIPAGIPRKPGMTRDD-LFKINA 96
                89*********98.6788888879**********************999*****************************999977766.778775 PP

>> Glyco_hydro_4  Family 4 glycosyl hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0    0.0026       9.3      58     104 ..      55     101 ..      15     104 .. 0.75
   2 ?    8.0   0.1   0.00053       1.9     124     149 ..      99     124 ..      94     142 .. 0.83

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0026
                    TCEEEEESSHHHHHTT-SEEEE---TTHHHHHHHHHHCCHTTTTT-C CS
  Glyco_hydro_4  58 dlkieattdrkealkdadfVitairvGlekareidekiplryGieqt 104
                       + a + +k+al+ ad+V++ + +  ++ +  d     + Gi+qt
     EEA18872.1  55 TGYLPADDGLKKALTGADIVVIPAGIPRKPGMTRDDLFKINAGIVQT 101
                    4555666779*************999999999999999999999986 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.00053
                    HHHHHHHHHHH-TTSEEEE-SSSHHH CS
  Glyco_hydro_4 124 lleIakdieelcPdawvlnytNPaav 149
                    +  ++k i e++P+a+vl  +NP+  
     EEA18872.1  99 VQTLVKGIAEFSPEAYVLIISNPVNS 124
                    5567999****************975 PP

>> THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.1   0.00019      0.67      38      91 ..       3      82 ..       2     126 .. 0.66

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00019
                   EEEEE---TTTHHHHHHHHHC.............T.............T-EEEEE-TTSCCHHHHHCCSSEEEE-SS-TT CS
  THF_DHG_CYH_C 38 kvvvvGrsnivgkplallLle.............k.............natVtvchsktkdlaeitreadivvvavGkpe 91
                   k+vv+G+s  +g+pl+ll+++             +              a +t    + + l++ +  adivv+ +G p+
     EEA18872.1  3 KAVVLGASGGIGQPLSLLFKAsplvdelalydvvNtpgvaadlshissPAKITGYLPADDGLKKALTGADIVVIPAGIPR 82
                   699****************9955555444444440444434444444456666666666778888888888888888654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (330 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       415  (0.0231469); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.44u 0.22s 00:00:00.66 Elapsed: 00:00:00.37
# Mc/sec: 2698.55
//
Query:       EEA18873.1  [L=330]
Description: malate dehydrogenase, NAD-dependent [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.9e-44  150.6   0.0    4.2e-44  150.1   0.0    1.2  1  Ldh_1_N        lactate/malate dehydrogenase, NAD binding doma
      1e-43  149.2   0.0    1.4e-43  148.7   0.0    1.2  1  Ldh_1_C        lactate/malate dehydrogenase, alpha/beta C-ter
    0.00028   20.0   0.0    0.00043   19.4   0.0    1.4  1  3Beta_HSD      3-beta hydroxysteroid dehydrogenase/isomerase 
  ------ inclusion threshold ------
       0.02   14.5   0.1        1.9    8.0   0.1    2.3  2  Glyco_hydro_4  Family 4 glycosyl hydrolase
      0.063   12.6   0.1       0.67    9.3   0.1    2.2  1  THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase,


Domain annotation for each model (and alignments):
>> Ldh_1_N  lactate/malate dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  150.1   0.0   1.2e-47   4.2e-44       2     141 .]       3     146 ..       2     146 .. 0.98

  Alignments for each domain:
  == domain 1  score: 150.1 bits;  conditional E-value: 1.2e-47
                 EEEEETTTSHHHHHHHHHHHHTTSSSEEEEE-SSHHHHHHHHHHHHHCHCCSTS-EEEEE..SSGGGGTTESEEEE--S-SS-TTTTHHHHHHHHHHHH CS
     Ldh_1_N   2 kvavvGaaGgiGqslalllankkladelaLlDiakekleGvaldlshistflsvkvkvse..keeealkdadvvvitagvprkpGetRddLlkvNakIv 98 
                 k +v+Ga+GgiGq+l+ll ++++l+delaL+D++  +++Gva+dlshis ++++ ++ ++  + ++al++ad+vvi+ag+prkpG+tRddL+k+Na+Iv
  EEA18873.1   3 KAVVLGASGGIGQPLSLLFKASPLVDELALYDVV--NTPGVAADLSHISSPAKITGYLPAddGLKKALTGADIVVIPAGIPRKPGMTRDDLFKINAGIV 99 
                 789*******************************..9********************9987789*********************************** PP

                 HHHHHHHHHHTTTSEEEE-SSSHH....HHHHHHHHHHTS-GGGEEE CS
     Ldh_1_N  99 keiveaiakvapnaivlvvsNPvd....iltevlkkasglpkkrvig 141
                 +++v+ ia+++p+a vl++sNPv+    i++evlk a+ +++kr++g
  EEA18873.1 100 QTLVKGIAEFSPEAYVLIISNPVNstvpIAAEVLKAAGVFNPKRLFG 146
                 *********************************************98 PP

>> Ldh_1_C  lactate/malate dehydrogenase, alpha/beta C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  148.7   0.0   3.9e-47   1.4e-43       1     167 []     148     324 ..     148     324 .. 0.92

  Alignments for each domain:
  == domain 1  score: 148.7 bits;  conditional E-value: 3.9e-47
                 THHHHHHHHHHHHHHHTS.-GGGEE--EEBSSSTETTEEHHHHHTTSTTSTHHHHHHHHHHHHHHHHHHHHHHTTSSSS-HHHHHHHHHHHHHHHTTHT CS
     Ldh_1_C   1 TtLDivRaktflaekagv.tprsvkvtViGgHsgvtiipllsqvkellklsekqleeliervqnggdevvkakkGagsatlsmAvAgakfveallrdtk 98 
                 TtLD+vRa+tf+ e +g  +p++  ++V+GgHsg ti+pl+sq+k + ++  +++++l++rvq+ggdevvkak+GagsatlsmA+Ag +f+e++++++k
  EEA18873.1 148 TTLDVVRAETFVQEWSGQkNPSETTIPVVGGHSGDTIVPLFSQAKPAFQIPADKYDALVNRVQFGGDEVVKAKDGAGSATLSMAYAGFRFAESVIKAVK 246
                 9*************999889******************************************************************************6 PP

                 EEEEEEEEEESCCCECCS..........SEEEEEEEEEEETTEEEEE-----.--HHHHHHHHHHHHHHHHHHHHHHCCH CS
     Ldh_1_C  99 eilsagvyldgevglkdq..........eieyfsvPvvlgknGvekvleilk.lndfeeekleksvkeLkkeiekglefv 167
                 ++  +g+++++ v l+            ++++fsvP+ lg++Gv++ +++l+  ++ e++ le ++k Lk +iekg++fv
  EEA18873.1 247 GE--KGIVEPSFVYLPGVpggeaiqkatGVDFFSVPIELGTDGVSNTINVLEnTTETEKKLLEVAIKGLKTNIEKGVDFV 324
                 66..666666666555555556668899*******************99988799999999***************9985 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.0   1.2e-07   0.00043       1      93 [.       5      96 ..       5     142 .. 0.90

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 1.2e-07
   3Beta_HSD  1 vvtGgaGFlGralvkeLvrlee.lkevrvlDlrespelleelskvnvkkviegDvtdkdkleealegvdvvihlaslvdvagkltedeimkvnv 93
                vv+G++G +G+ l + L+++ + + e+  +D+++ p +  +ls++     i+g +   d l++al g+d+v+  a++    g++++d + k+n 
  EEA18873.1  5 VVLGASGGIGQPL-SLLFKASPlVDELALYDVVNTPGVAADLSHISSPAKITGYLPADDGLKKALTGADIVVIPAGIPRKPGMTRDD-LFKINA 96
                89*********98.6788888879**********************999*****************************999977766.778775 PP

>> Glyco_hydro_4  Family 4 glycosyl hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0    0.0026       9.3      58     104 ..      55     101 ..      15     104 .. 0.75
   2 ?    8.0   0.1   0.00053       1.9     124     149 ..      99     124 ..      94     142 .. 0.83

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0026
                    TCEEEEESSHHHHHTT-SEEEE---TTHHHHHHHHHHCCHTTTTT-C CS
  Glyco_hydro_4  58 dlkieattdrkealkdadfVitairvGlekareidekiplryGieqt 104
                       + a + +k+al+ ad+V++ + +  ++ +  d     + Gi+qt
     EEA18873.1  55 TGYLPADDGLKKALTGADIVVIPAGIPRKPGMTRDDLFKINAGIVQT 101
                    4555666779*************999999999999999999999986 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.00053
                    HHHHHHHHHHH-TTSEEEE-SSSHHH CS
  Glyco_hydro_4 124 lleIakdieelcPdawvlnytNPaav 149
                    +  ++k i e++P+a+vl  +NP+  
     EEA18873.1  99 VQTLVKGIAEFSPEAYVLIISNPVNS 124
                    5567999****************975 PP

>> THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.1   0.00019      0.67      38      91 ..       3      82 ..       2     126 .. 0.66

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00019
                   EEEEE---TTTHHHHHHHHHC.............T.............T-EEEEE-TTSCCHHHHHCCSSEEEE-SS-TT CS
  THF_DHG_CYH_C 38 kvvvvGrsnivgkplallLle.............k.............natVtvchsktkdlaeitreadivvvavGkpe 91
                   k+vv+G+s  +g+pl+ll+++             +              a +t    + + l++ +  adivv+ +G p+
     EEA18873.1  3 KAVVLGASGGIGQPLSLLFKAsplvdelalydvvNtpgvaadlshissPAKITGYLPADDGLKKALTGADIVVIPAGIPR 82
                   699****************9955555444444440444434444444456666666666778888888888888888654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (330 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       415  (0.0231469); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.39
# Mc/sec: 2512.59
//
Query:       EEA18874.1  [L=330]
Description: malate dehydrogenase, NAD-dependent [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.9e-44  150.6   0.0    4.2e-44  150.1   0.0    1.2  1  Ldh_1_N        lactate/malate dehydrogenase, NAD binding doma
      1e-43  149.2   0.0    1.4e-43  148.7   0.0    1.2  1  Ldh_1_C        lactate/malate dehydrogenase, alpha/beta C-ter
    0.00028   20.0   0.0    0.00043   19.4   0.0    1.4  1  3Beta_HSD      3-beta hydroxysteroid dehydrogenase/isomerase 
  ------ inclusion threshold ------
       0.02   14.5   0.1        1.9    8.0   0.1    2.3  2  Glyco_hydro_4  Family 4 glycosyl hydrolase
      0.063   12.6   0.1       0.67    9.3   0.1    2.2  1  THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase,


Domain annotation for each model (and alignments):
>> Ldh_1_N  lactate/malate dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  150.1   0.0   1.2e-47   4.2e-44       2     141 .]       3     146 ..       2     146 .. 0.98

  Alignments for each domain:
  == domain 1  score: 150.1 bits;  conditional E-value: 1.2e-47
                 EEEEETTTSHHHHHHHHHHHHTTSSSEEEEE-SSHHHHHHHHHHHHHCHCCSTS-EEEEE..SSGGGGTTESEEEE--S-SS-TTTTHHHHHHHHHHHH CS
     Ldh_1_N   2 kvavvGaaGgiGqslalllankkladelaLlDiakekleGvaldlshistflsvkvkvse..keeealkdadvvvitagvprkpGetRddLlkvNakIv 98 
                 k +v+Ga+GgiGq+l+ll ++++l+delaL+D++  +++Gva+dlshis ++++ ++ ++  + ++al++ad+vvi+ag+prkpG+tRddL+k+Na+Iv
  EEA18874.1   3 KAVVLGASGGIGQPLSLLFKASPLVDELALYDVV--NTPGVAADLSHISSPAKITGYLPAddGLKKALTGADIVVIPAGIPRKPGMTRDDLFKINAGIV 99 
                 789*******************************..9********************9987789*********************************** PP

                 HHHHHHHHHHTTTSEEEE-SSSHH....HHHHHHHHHHTS-GGGEEE CS
     Ldh_1_N  99 keiveaiakvapnaivlvvsNPvd....iltevlkkasglpkkrvig 141
                 +++v+ ia+++p+a vl++sNPv+    i++evlk a+ +++kr++g
  EEA18874.1 100 QTLVKGIAEFSPEAYVLIISNPVNstvpIAAEVLKAAGVFNPKRLFG 146
                 *********************************************98 PP

>> Ldh_1_C  lactate/malate dehydrogenase, alpha/beta C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  148.7   0.0   3.9e-47   1.4e-43       1     167 []     148     324 ..     148     324 .. 0.92

  Alignments for each domain:
  == domain 1  score: 148.7 bits;  conditional E-value: 3.9e-47
                 THHHHHHHHHHHHHHHTS.-GGGEE--EEBSSSTETTEEHHHHHTTSTTSTHHHHHHHHHHHHHHHHHHHHHHTTSSSS-HHHHHHHHHHHHHHHTTHT CS
     Ldh_1_C   1 TtLDivRaktflaekagv.tprsvkvtViGgHsgvtiipllsqvkellklsekqleeliervqnggdevvkakkGagsatlsmAvAgakfveallrdtk 98 
                 TtLD+vRa+tf+ e +g  +p++  ++V+GgHsg ti+pl+sq+k + ++  +++++l++rvq+ggdevvkak+GagsatlsmA+Ag +f+e++++++k
  EEA18874.1 148 TTLDVVRAETFVQEWSGQkNPSETTIPVVGGHSGDTIVPLFSQAKPAFQIPADKYDALVNRVQFGGDEVVKAKDGAGSATLSMAYAGFRFAESVIKAVK 246
                 9*************999889******************************************************************************6 PP

                 EEEEEEEEEESCCCECCS..........SEEEEEEEEEEETTEEEEE-----.--HHHHHHHHHHHHHHHHHHHHHHCCH CS
     Ldh_1_C  99 eilsagvyldgevglkdq..........eieyfsvPvvlgknGvekvleilk.lndfeeekleksvkeLkkeiekglefv 167
                 ++  +g+++++ v l+            ++++fsvP+ lg++Gv++ +++l+  ++ e++ le ++k Lk +iekg++fv
  EEA18874.1 247 GE--KGIVEPSFVYLPGVpggeaiqkatGVDFFSVPIELGTDGVSNTINVLEnTTETEKKLLEVAIKGLKTNIEKGVDFV 324
                 66..666666666555555556668899*******************99988799999999***************9985 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.0   1.2e-07   0.00043       1      93 [.       5      96 ..       5     142 .. 0.90

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 1.2e-07
   3Beta_HSD  1 vvtGgaGFlGralvkeLvrlee.lkevrvlDlrespelleelskvnvkkviegDvtdkdkleealegvdvvihlaslvdvagkltedeimkvnv 93
                vv+G++G +G+ l + L+++ + + e+  +D+++ p +  +ls++     i+g +   d l++al g+d+v+  a++    g++++d + k+n 
  EEA18874.1  5 VVLGASGGIGQPL-SLLFKASPlVDELALYDVVNTPGVAADLSHISSPAKITGYLPADDGLKKALTGADIVVIPAGIPRKPGMTRDD-LFKINA 96
                89*********98.6788888879**********************999*****************************999977766.778775 PP

>> Glyco_hydro_4  Family 4 glycosyl hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0    0.0026       9.3      58     104 ..      55     101 ..      15     104 .. 0.75
   2 ?    8.0   0.1   0.00053       1.9     124     149 ..      99     124 ..      94     142 .. 0.83

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0026
                    TCEEEEESSHHHHHTT-SEEEE---TTHHHHHHHHHHCCHTTTTT-C CS
  Glyco_hydro_4  58 dlkieattdrkealkdadfVitairvGlekareidekiplryGieqt 104
                       + a + +k+al+ ad+V++ + +  ++ +  d     + Gi+qt
     EEA18874.1  55 TGYLPADDGLKKALTGADIVVIPAGIPRKPGMTRDDLFKINAGIVQT 101
                    4555666779*************999999999999999999999986 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.00053
                    HHHHHHHHHHH-TTSEEEE-SSSHHH CS
  Glyco_hydro_4 124 lleIakdieelcPdawvlnytNPaav 149
                    +  ++k i e++P+a+vl  +NP+  
     EEA18874.1  99 VQTLVKGIAEFSPEAYVLIISNPVNS 124
                    5567999****************975 PP

>> THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.1   0.00019      0.67      38      91 ..       3      82 ..       2     126 .. 0.66

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00019
                   EEEEE---TTTHHHHHHHHHC.............T.............T-EEEEE-TTSCCHHHHHCCSSEEEE-SS-TT CS
  THF_DHG_CYH_C 38 kvvvvGrsnivgkplallLle.............k.............natVtvchsktkdlaeitreadivvvavGkpe 91
                   k+vv+G+s  +g+pl+ll+++             +              a +t    + + l++ +  adivv+ +G p+
     EEA18874.1  3 KAVVLGASGGIGQPLSLLFKAsplvdelalydvvNtpgvaadlshissPAKITGYLPADDGLKKALTGADIVVIPAGIPR 82
                   699****************9955555444444440444434444444456666666666778888888888888888654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (330 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       415  (0.0231469); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2292.36
//
Query:       EEA18875.1  [L=198]
Description: BET3 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-45  154.9   0.0    1.3e-45  154.7   0.0    1.1  1  TRAPP     Transport protein particle (TRAPP) component


Domain annotation for each model (and alignments):
>> TRAPP  Transport protein particle (TRAPP) component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  154.7   0.0   7.4e-50   1.3e-45       2     144 ..      25     192 ..      24     194 .. 0.90

  Alignments for each domain:
  == domain 1  score: 154.7 bits;  conditional E-value: 7.4e-50
       TRAPP   2 afllgelvsylqrdskdveeve.......................krLekmGyrvGlrllelllarerpretdilevlkfickdlWkllfgkqidnlkt 77 
                 ++ll+e+v+++ r ++d+   +                        rLe +GyrvG++l+e +++r+rpr+td l+++kfickdlW++lf+kq+dnlkt
  EEA18875.1  25 DLLLIEIVPMAERITQDLLVNStttdgtnnavakiedeelqeatfYRLEMLGYRVGQGLAE-RFSRDRPRFTDNLDAIKFICKDLWTILFRKQVDNLKT 122
                 899********999988754448899999********************************.************************************* PP

       TRAPP  78 nhrgeyvltdnef.pltrf...velpke..ls...ylaflcGiirGaLenlgfpakVta..helpsdelrgrttfeik 144
                 nhrg+yvl+dn+f pltr+   v   +e  ++   +l+f+cG+irG+L++lg++a+V+a  +elp       +tf+ik
  EEA18875.1 123 NHRGVYVLSDNAFrPLTRMsmaV--RSEavARaeaFLWFPCGLIRGCLASLGIDATVQAetSELPG------ATFQIK 192
                 *******************6431..3335522557************************7667777......999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (198 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       385  (0.0214736); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.43
# Mc/sec: 1379.66
//
Query:       EEA18876.1  [L=853]
Description: snRNA cap binding complex subunit (Gcr3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.3e-89  298.2   0.1      4e-89  297.4   0.1    1.4  1  MIF4G_like    MIF4G like
    6.6e-74  248.7   0.0    1.2e-73  247.9   0.0    1.4  1  MIF4G_like_2  MIF4G like
  ------ inclusion threshold ------
       0.22   11.1   0.3          1    9.0   0.0    2.2  3  MIF4G         MIF4G domain


Domain annotation for each model (and alignments):
>> MIF4G_like  MIF4G like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  297.4   0.1   6.7e-93     4e-89       3     191 .]     345     533 ..     343     533 .. 0.99

  Alignments for each domain:
  == domain 1  score: 297.4 bits;  conditional E-value: 6.7e-93
  MIF4G_like   3 asslaavllrdilvdvinllevnrkeaakllldldlyltkktfalratsvdklkdldppestwkledvvveavlsellqlptpekklvyyhsllteick 101
                   ++ ++llrd+lvd+in++++nr ++ak+l+d+d+y+++  f++rat++dkl++  ++++twk+edv+v+av+s+l+qlp pe+klvyyhs+lte+ck
  EEA18876.1 345 SGEITSTLLRDALVDTINIMDFNRMAVAKFLIDVDCYFSPGIFVKRATPFDKLREFPTDKPTWKPEDVAVDAVFSQLFQLPAPEHKLVYYHSVLTECCK 443
                 567899********************************************************************************************* PP

  MIF4G_like 102 laPkavaPslGrairllyaalssldvelierfldWfshhlsnfgftWkWkeWvedvelpalhPrkvfikrviekeirlsyadriketlPd 191
                 +aP+a+aPslGrair+ly++l+++dv+l++rfldWfshhlsnfgftWkW+eW++d++lp++hP+++fi+++++keirls+a+rik tlP+
  EEA18876.1 444 IAPAAIAPSLGRAIRFLYRNLERFDVDLVSRFLDWFSHHLSNFGFTWKWTEWIDDLQLPEIHPKMAFITGALDKEIRLSFAQRIKGTLPE 533
                 *****************************************************************************************7 PP

>> MIF4G_like_2  MIF4G like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  247.9   0.0     2e-77   1.2e-73       1     265 [.     550     802 ..     550     804 .. 0.94

  Alignments for each domain:
  == domain 1  score: 247.9 bits;  conditional E-value: 2e-77
  MIF4G_like_2   1 fkyedeslPfaaeaqelldlirkkapaeevlelldeikesaeeegsieadpdslsidvfvqtllhvGskSlSHvlsaierykevLkel.aeseeara 96 
                   fky+ e +P+++++ el++lirkka++ee+++++ ei+++a+e+g  ++dp ++s+d+fv+++++vGskSlSHvls+ier ke+L+++  +s+  r+
    EEA18876.1 550 FKYTLETTPYSKQGLELMQLIRKKASDEEIEPVIAEIETQAKEHG--IEDPIVPSTDAFVTSICYVGSKSLSHVLSCIERNKERLLAIgPRSAPGRR 644
                   9****************************************9997..689999***********************************9999***** PP

  MIF4G_like_2  97 qileavmrfWknnpqmaiiivdkLlnyqivepasVvewifs..keknegltrayvwEllkrtlskvnkrvkkvrqeleelkkkeeeekakeeedkee 191
                   qi+++vm++W ++p++ai+i+dkLlny+i++p sV+ew++    +++  l++a+++E+l++t+ kv++r   +rq +++ +++           +  
    EEA18876.1 645 QIITSVMEYWVDQPGIAINIIDKLLNYTILTPLSVIEWALLdhIDAGRILAKAHIYEMLSSTVGKVTNR---IRQIVAARTQR-----------GLY 727
                   *****************************************99779***********************...*****666666...........999 PP

  MIF4G_like_2 192 eeeleraeekleaaqkeqkelflivferlveilses.leeletsgseentevieewkkwwikrllkvflrkyave 265
                   e++l+ ++e+l++++++++ lf +++++++ ++++s  e +e s+++ +t + +e +++w+ r+ +vf rk+ave
    EEA18876.1 728 EPQLSVLDETLNREKADMQTLFTLIEDSIAPVAAGSnDELMERSEDDPSTRDENEIIRRWAVRWRRVFQRKAAVE 802
                   ************************************755555666666666667******************998 PP

>> MIF4G  MIF4G domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.0   0.00017         1      28     138 ..      73     171 ..      64     216 .. 0.76
   2 ?   -2.1   0.0      0.41   2.4e+03      54      85 ..     451     481 ..     417     486 .. 0.79
   3 ?   -3.6   0.0       1.2   7.1e+03       2      23 ..     565     586 ..     564     591 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00017
                 HCSCHHHHHHHHHHHHHHHHHCGGGHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHC-S-HHHHHHHHHHHHHHHHHHHHHHHHHHTTSSEHHHHH CS
       MIF4G  28 mdddknelkevielifekaveepsfsplyarlcgklnsrfqqnFrikllnklqeefekryeleneleenedgnrrrrlglvrflgelfklkmltskill 126
                 +++d++ ++ + e++++ ++e+p ++p +a ++  +n+  + +F +  l k   + ++            +g +r ++ lvr+lg    +++++ + ++
  EEA18876.1  73 NTEDEDVRDAFFETVIQLTLEQPFKIPFIAAIVLVINTLKP-DFAAEGLKKASSATQD---------ALNAGVWRDVKLLVRLLGC--LQGIFEGDGVF 159
                 344689***********************************.9999888887777777.........7777777777777777763..45556666666 PP

                 HHHHHHHHGGCC CS
       MIF4G 127 dclkellssltk 138
                 ++l++l+s   +
  EEA18876.1 160 VILEDLFSRAVD 171
                 666666666555 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.41
                 HHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHH CS
       MIF4G  54 plyarlcgklnsrfqqnFrikllnklqeefek 85 
                 p + r ++ l+  ++ +F   l+++++ +f +
  EEA18876.1 451 PSLGRAIRFLYRNLE-RFDVDLVSRFLDWFSH 481
                 455555666666667.9999999999999976 PP

  == domain 3  score: -3.6 bits;  conditional E-value: 1.2
                 HHHHHHHHCHTTTTHHHHHHHH CS
       MIF4G   2 kkvkgilnklskenfevlikql 23 
                 + +++i++k s+e +e+ i ++
  EEA18876.1 565 ELMQLIRKKASDEEIEPVIAEI 586
                 5688999999999999999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (853 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       626  (0.0349155); expected 358.6 (0.02)
Passed bias filter:                      550  (0.0306766); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.72u 0.27s 00:00:00.99 Elapsed: 00:00:00.42
# Mc/sec: 6069.32
//
Query:       EEA18877.1  [L=394]
Description: glycogen synthase kinase (Skp1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.9e-66  222.3   0.0    8.1e-66  222.1   0.0    1.0  1  Pkinase         Protein kinase domain
    1.4e-25   90.0   0.0    1.9e-25   89.6   0.0    1.2  1  Pkinase_Tyr     Protein tyrosine kinase
    1.3e-06   27.9   0.0    1.3e-05   24.7   0.0    2.0  2  Kinase-like     Kinase-like
     0.0017   18.3   0.9      0.012   15.6   0.0    2.3  3  APH             Phosphotransferase enzyme family
  ------ inclusion threshold ------
       0.12   12.0   0.0       0.19   11.3   0.0    1.3  1  Choline_kinase  Choline/ethanolamine kinase
       0.12   11.7   0.0       0.21   10.9   0.0    1.3  1  Kdo             Lipopolysaccharide kinase (Kdo/WaaP) family


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  222.1   0.0   2.7e-69   8.1e-66       1     264 []      35     318 ..      35     318 .. 0.89

  Alignments for each domain:
  == domain 1  score: 222.1 bits;  conditional E-value: 2.7e-69
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHSCTTB--EEEEEEE....SSEEE..EEEE--TTEB..HHHHHH. CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklkhpnivrlyevfee....kdely..lvleyvegge..ladlle. 90 
                 y++ + +G+GsfG+V++ + + +g+  A+K++ ++k+ k+      rE++i++ ++hpniv+l+ ++++    kde+y  lvleyv+++        + 
  EEA18877.1  35 YTQCKIVGNGSFGVVFQTKMSPSGEDAAIKRVLQDKRFKN------RELQIMRIVRHPNIVELKAFYYSngerKDEVYlnLVLEYVPETVyrA---SRy 124
                 678899****************************999883......69*******************99999955555559******886442...223 PP

                 ...HHSS--HHHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEE.TTTEEEE-SGTTSEESSSSCSBCTTTSCGGGS-HHHH.TTSCBSHHHHHHHHH CS
     Pkinase  91 ...rkgslseeeakkiakqilegleylHskgiiHrDlKpeNiLid.ekgelKitDFGlakelessskltsfvgtseYlAPEvl.keneyskkvDvWslG 184
                     k+++++ e+k +++q++++l+y+Hs+gi+HrD+Kp+N+L+d ++g lK++DFG ak l ++++  s++++++Y+APE++ ++++y++k+DvWs G
  EEA18877.1 125 fnkLKTTMPMLEVKLYIYQLFRSLAYIHSRGICHRDIKPQNLLLDpNTGILKLCDFGSAKILVENEPNVSYICSRYYRAPELIfGATNYTTKIDVWSTG 223
                 33445679999**********************************99999************************************************* PP

                 HHHHHHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCT...SHH...HHHTTS.....................-HHHHHHHHHHT-SSGCCSTTHHHHH CS
     Pkinase 185 vilyelltgkppfsgekgkekvekeldqlekilkilg...etkeklpeasei.....................seeakdllkkllkkdpkkRltaeell 259
                 ++++el+ g+p+f+   g++     +dql++i+k+lg      e++++ +                       ++ea+dl++ ll+++p++Rl a e++
  EEA18877.1 224 CVMAELMLGQPLFP---GES----GIDQLVEIIKVLGtptR--EQIRTMNPNymehkfpqikphpfnkvfrraPHEAIDLISALLEYTPTQRLRAIEAM 313
                 **************...544....899*********97442..333322222558899999************************************** PP

                 TSGGG CS
     Pkinase 260 qhpyl 264
                  hp++
  EEA18877.1 314 CHPFF 318
                 ****8 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.6   0.0   6.4e-29   1.9e-25       4     208 ..      38     238 ..      35     275 .. 0.83

  Alignments for each domain:
  == domain 1  score: 89.6 bits;  conditional E-value: 6.4e-29
                  EEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS-BTTB--EEEEEESSSS......EEEEEE--TTE..BHHHHHH CS
  Pkinase_Tyr   4 gkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkklkhpnivkllgvctkeep......llivteyvkgG..dLlkfLr 93 
                   k +G+G+fG V++ +++     + ++ a+K + ++++ +      +e++im+ ++hpniv+l ++++++++      l +v+eyv++     + + +
   EEA18877.1  38 CKIVGNGSFGVVFQTKMS----PSGEDAAIKRVLQDKRFK-----NRELQIMRIVRHPNIVELKAFYYSNGErkdevyLNLVLEYVPETvyRASRYFN 126
                  5789*************9....788899****96666655.....57********************94443355667889******99556678999 PP

                  HTCTTTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEETT.EEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSE.EEHHHHHH CS
  Pkinase_Tyr  94 kkekekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsenk.vvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekk.ftsksDvW 189
                  k  k+++ + ++  +++q+ + ++y++s+ + Hrd+  +N Ll+ n+ + k++DfG a+ + +    + + +  ++  + apE ++  + +t+k DvW
   EEA18877.1 127 KL-KTTMPMLEVKLYIYQLFRSLAYIHSRGICHRDIKPQNLLLDPNTgILKLCDFGSAKILVE---NEPNVSYICSRYYRAPELIFGATnYTTKIDVW 220
                  99.99***************************************865599********99933...34445566777788*****98766******** PP

                  HHHHHHHHHHTTSSGTTTT CS
  Pkinase_Tyr 190 sfGvllwEiftlgespypg 208
                  s G ++ E++  g+  +pg
   EEA18877.1 221 STGCVMAELML-GQPLFPG 238
                  *********97.7665554 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0      0.11   3.3e+02      13      56 ..      34      77 ..      27      85 .. 0.81
   2 !   24.7   0.0   4.4e-09   1.3e-05     146     240 ..     138     226 ..     125     231 .. 0.81

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.11
  Kinase-like 13 tlvrgellkkgdrsvvfevkdqetgeplavkvfllpseaskkdl 56
                 ++ + +++++g ++vvf+ k    ge+ a+k  l  ++  +++l
   EEA18877.1 34 QYTQCKIVGNGSFGVVFQTKMSPSGEDAAIKRVLQDKRFKNREL 77
                 66778999**********************99887776655555 PP

  == domain 2  score: 24.7 bits;  conditional E-value: 4.4e-09
  Kinase-like 146 rlllTlqlirlaanLqakglvhgkftvdnllldekgg.lmlggftaLvr.agtkvvlseve.kgfaPpEllgsrggytrknktkmthkldaWqlGlvi 240
                  +l++  ql r  a+++++g+ h +++++nllld++ g l+l +f++    + ++  +s ++ + +  pEl+           t++t k+d+W  G v+
   EEA18877.1 138 KLYI-YQLFRSLAYIHSRGICHRDIKPQNLLLDPNTGiLKLCDFGSAKIlVENEPNVSYICsRYYRAPELIFG--------ATNYTTKIDVWSTGCVM 226
                  5566.7999************************9755379****87543033344447777689999999866........489999******99885 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0      0.25   7.5e+02      31     103 ..      69     149 ..      53     154 .. 0.65
   2 !   15.6   0.0   3.9e-06     0.012     165     194 ..     153     181 ..     147     185 .. 0.77
   3 ?   -1.2   0.1      0.53   1.6e+03     103     141 ..     299     344 ..     272     380 .. 0.50

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.25
                 TS-HHHHHHHHHHHHHHHHTT-B--B-CTTB.S-EEETTEEEEEEE----EE-SS.........HHHHHHHHHHHHHHHHHHC CS
         APH  31 araaeeirrevallrlLakagvpvPevlagd.tddeeigllfalieyvpgrsllr.........klsaaqlpellealgefla 103
                    +++  re++++r ++  ++   +++++    + ++ +l +++eyvp ++++          ++ + + + ++++l + la
  EEA18877.1  69 D--KRFKNRELQIMRIVRHPNIVELKAFYYSnGERKDEVYLNLVLEYVPETVYRAsryfnklktTMPMLEVKLYIYQLFRSLA 149
                 4..666778888888888777744455555425555566699999***99999886666666555555555555555555555 PP

  == domain 2  score: 15.6 bits;  conditional E-value: 3.9e-06
                 -EEEE-SS-SGGGEEEC..TTEEEEE---T CS
         APH 165 ptvllHgDlhpgNllvdpddgrvtGviDfe 194
                 +++++H+D++p+Nll+dp+ g +  + Df+
  EEA18877.1 153 SRGICHRDIKPQNLLLDPNTGIL-KLCDFG 181
                 589**************775544.555555 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 0.53
                 C......CHHCH.-STTTB-SHHCHTCCHHHHHHCHHH.CCCGCCT CS
         APH 103 a......alhqvdpaalpladflaqdlellrqlesata.rllasel 141
                        +l ++++   p++d+l++  + l++     + +++ ++l
  EEA18877.1 299 LeytptqRLRAIEAMCHPFFDELRDPNTRLPDSRHPSNpARDLPNL 344
                 4444444444444444555555544444433332222223333333 PP

>> Choline_kinase  Choline/ethanolamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   6.2e-05      0.19     145     171 ..     154     180 ..     110     186 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 6.2e-05
                     EEEE-S--SGGGEEE.-CTTEEEE--G CS
  Choline_kinase 145 vvfcHnDlqegNillnkeekklvlIDF 171
                        cH D+ ++N+ll+ +++ l l DF
      EEA18877.1 154 RGICHRDIKPQNLLLDPNTGILKLCDF 180
                     578***********************9 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   6.9e-05      0.21     129     155 ..     146     172 ..     123     185 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 6.9e-05
         Kdo 129 rliaklhragvnHadlyaknillqqee 155
                 r  a +h++g++H+d+ ++n+ll+ + 
  EEA18877.1 146 RSLAYIHSRGICHRDIKPQNLLLDPNT 172
                 667789*****************9886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (394 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       444  (0.0247643); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 2659.45
//
Query:       EEA18878.1  [L=355]
Description: mitochondrial import receptor subunit (tom40), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-83  280.3   0.1    1.9e-83  280.1   0.1    1.0  1  Porin_3   Eukaryotic porin
  ------ inclusion threshold ------
       0.01   15.6   0.0      0.026   14.3   0.0    1.6  1  Zds_C     Activator of mitotic machinery Cdc14 phosphatase ac


Domain annotation for each model (and alignments):
>> Porin_3  Eukaryotic porin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  280.1   0.1   2.1e-87   1.9e-83       1     270 []      38     326 ..      38     326 .. 0.98

  Alignments for each domain:
  == domain 1  score: 280.1 bits;  conditional E-value: 2.1e-87
                 S---CCCCCHHH.HHHHHCCHTTTECEEEEEEEECCECCEEEEEEEETTTS..-ECEEEEEEEEETCCCEEEEEECCCSCCEEEEEECCSSTTCEEEEE CS
     Porin_3   1 nPgtyedlgkea.kdllpkdYhfeglkldvtkktslgvaFqvshsfslgsg..kvsysfeakykdkgltltlkgntdndlsltarvneqlaeglklkls 96 
                 nPgt++++ +e+ k++l+ +++f+gl++d+tk++++ + F  sh f +gs    ++y+f+a+y    ++++++gn+ +d+ l+a  n++++e++ +k +
  EEA18878.1  38 NPGTVDNIAREVqKEVLLSNFMFTGLRADLTKVFGMTPLFRMSHAFAMGSAgnMPPYNFSAMYG--TPKVFMQGNLGSDGGLSAVGNYRWNEKFVTKSN 134
                 8***************************************************************..********************************* PP

                 EEE-TTT--EEEEEEEEEEETTEEEEEEEEC.TC.....EEEEEEEEEEECTSTEEEEEEEEEECTTTCCEEEEEEEEEEEC....SEEEEEEEEETTT CS
     Porin_3  97 aqltpekgkksakleldykgddftaslklgn.sk.....tpvvvasllqsvtpglalGaeavydtasgkltkyaaalsyaar....dwiaslqllnngg 185
                 aq+ ++  +   +++ dy+gddf++slk+ n s      t+++v+s+lqsvtpglalG+ea++++++  + +++  lsy+a+    dwias+ql +++g
  EEA18878.1 135 AQIMSGGAQGILQIDNDYTGDDFSFSLKAFNpSIfegglTGIYVGSYLQSVTPGLALGFEAIWQRQAITSRPESS-LSYCAKyrgeDWIASAQL-QAQG 231
                 ******999999*******************888********************************988888887.*****************8.89** PP

                 EEEEEEEEECCTTEEEEEEEEEETTEE...........EEEEEEEEEEEECTCEEEEEEEECTTEEEEEEEEEECTTEEEEEEEEEECCCTEEEEE CS
     Porin_3 186 altasyyqkvsekvevgaeltlnassq...........estttlGakydldksttvkakidsngkvgllleqkLrpgvtltlsaelDhkknahkfG 270
                 a+ asy++k+s+kve+g++++l++ ++           e+t+t+Gakyd++ s t++a++ds+gkv++lle+++ ++++lt+++e+Dh+k+++k+G
  EEA18878.1 232 AIAASYWKKLSDKVEAGVDMNLQLAPSaaammmggpsrEGTATVGAKYDFRAS-TFRAQVDSAGKVSCLLEKRIAMPISLTFAGEIDHVKQQAKVG 326
                 *****************************************************.*****************************************9 PP

>> Zds_C  Activator of mitotic machinery Cdc14 phosphatase activation C-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   2.9e-06     0.026      29      48 ..      44      63 ..      42      65 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2.9e-06
       Zds_C 29 nprRpLreQVLlSNfMYsYL 48
                n  R+ ++ VLlSNfM++ L
  EEA18878.1 44 NIAREVQKEVLLSNFMFTGL 63
                66799************865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (355 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       295  (0.0164538); expected 358.6 (0.02)
Passed bias filter:                      263  (0.014669); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 2441.33
//
Query:       EEA18879.1  [L=534]
Description: 6-phosphofructo-2-kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.8e-62  210.6   0.0    2.7e-62  210.0   0.0    1.3  1  6PF2K       6-phosphofructo-2-kinase
    1.6e-20   73.6   0.6    9.4e-20   71.1   0.6    2.0  1  His_Phos_1  Histidine phosphatase superfamily (branch 1)
  ------ inclusion threshold ------
      0.036   13.5   0.0      0.076   12.4   0.0    1.5  1  KTI12       Chromatin associated protein KTI12
       0.04   13.8   0.1       0.43   10.5   0.1    2.2  1  APS_kinase  Adenylylsulphate kinase
       0.12   12.6   0.0       0.27   11.4   0.0    1.7  1  AAA_33      AAA domain


Domain annotation for each model (and alignments):
>> 6PF2K  6-phosphofructo-2-kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  210.0   0.0   7.4e-66   2.7e-62       4     222 ..      45     264 ..      42     265 .. 0.93

  Alignments for each domain:
  == domain 1  score: 210.0 bits;  conditional E-value: 7.4e-66
                 XHHHHT..S-EEEEEESSTTSSHHHHHHHHHHHHHHTT--EEEEEHHHHHHHHHSS...---GGGGSTT-HHHHHHHHHHHHHHHHHHHHHHHTS--SE CS
       6PF2K   4 stvtnlknsklvivlvGLpargKtyiskkltrylkwlgvrtkvFnvgkyrreaska...lsdaeffrpdneealklreklalaalkdllaylneeegqv 99 
                 +++  +++ ++vi+ vGLpargKt is++l ryl+wlgv+t++F++g+yrr +        d  ff   ++ ++ lr+k+ ++  +d++++l+ee+gq+
  EEA18879.1  45 ESGRLFHSGRIVIITVGLPARGKTHISVALARYLRWLGVKTRIFHLGDYRRATIGPgqdMPDDYFFVNASASSVLLRQKIVKKCRDDIAHFLSEENGQI 143
                 566778999*******************************************99885554455688889999*************************** PP

                 EEEES---SHHHHHHHHHHHHHTT-EEEEEEEE--HHHHHHHHHHHHTTTSGGGTTS-HHHHHHHHHHHHHHHHTT-----TTTTTTSEEEEEETTTTE CS
       6PF2K 100 aifDAtNttrerRklilefveennlkvlflesicsdeeiikeNikevklsspDYkdketeeaikdflkRlenyekqyeplddeedeelsyIkvidvgks 198
                 ai+DA+N     R+ + +++ ++n+++lf+es+c+d++ii+eN++ vk+sspDY + + + a+k +l R++    + e ++   +++l+yIk+i++g++
  EEA18879.1 144 AIYDAVNPIAAGRRSLAKEFAKQNIETLFIESMCDDPKIIEENVRRVKISSPDYVGWDANDAVKHYLGRISARIPHVETME---EKDLNYIKMINAGER 239
                 ********************************************************************************9...899********9999 PP

                 EEEE-.--SHHHHHHHHHHTT---S CS
       6PF2K 199 lvvnn.vqgylqsrivyyllNihlk 222
                 l+vnn   gyl +riv+yllN+h k
  EEA18879.1 240 LIVNNrSFGYLSNRIVFYLLNLHIK 264
                 88876167**************976 PP

>> His_Phos_1  Histidine phosphatase superfamily (branch 1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.1   0.6   2.6e-23   9.4e-20      22     171 ..     285     449 ..     269     469 .. 0.80

  Alignments for each domain:
  == domain 1  score: 71.1 bits;  conditional E-value: 2.6e-23
                 ---B-HHHHHHHHHHHHHHTTS---EE..................EE-SSHHHHHHHHHHHHCTT--EEE-GGGS----GGGTT-B.HHHHHH..HSHH CS
  His_Phos_1  22 dvpLteeGreqAealaerlagepidai..................ysSplkRarqTaeliaealglpveldegLrEidfGdweglttaeiaeeypeele 102
                 d+ L+e+G+  A+++ e + +++ + +                  ++S+  R+++Ta+ + e  g  v+++ +L  ++ G++e++t ++i++eypee +
  EEA18879.1 285 DSSLSERGQDYAKKMTETILQHRASELqamkaqgesdaalkpltvWTSTRLRTVETAKWLHE-KGYAVRQRSQLSQLNPGVCEKMTEQQIRQEYPEEVA 382
                 555666666666665555333333333333444444445555566*************9997.7*********************************** PP

                 HHHHHHH-GGG-BS-BHHHHHHHHHHHHHHHHHHTTTSEEEEEE-HHHHHHHHHHHHT--GGGGGGB-- CS
  His_Phos_1 103 awlrdpadvrppggEsledvaaRvaaaleelaarhegetvlvVsHggvirallarllglpleelrrlel 171
                 +++ dp+++r+p+ Es++d+a R+++++ el++++++  +l+++H  v+r+l+ +l+ ++ ++++ l +
  EEA18879.1 383 KHEIDPYHHRYPRAESYHDLAVRLEPIILELEREQND--LLIIAHESVLRVLYGYLMACNATDIPFLSF 449
                 **********************************997..9*****************999988776665 PP

>> KTI12  Chromatin associated protein KTI12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   2.1e-05     0.076       4     119 ..      57     189 ..      55     212 .. 0.71

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2.1e-05
                 EEEE--TTSSHHHHHHHHHHHHHHTT--EEEE-THHHH..........TTSS..S--GGGHHHHHHHHHH....HHHHHHTT...SEEEE-S---SHHH CS
       KTI12   4 vvltGlPssGKstrakeLakaleeekrsvvviddeslg.........iekds..ykdsakekalRsslrs....avkrdLske..kvVIvDslnyikgf 85 
                 ++  GlP+ GK+ ++  La++l+  + +  +     ++         +  d   ++ sa+   lR+++ +    +++  Ls+e  ++ I D++n i   
  EEA18879.1  57 IITVGLPARGKTHISVALARYLRWLGVKTRIFHLGDYRratigpgqdMPDDYffVNASASSVLLRQKIVKkcrdDIAHFLSEEngQIAIYDAVNPIAAG 155
                 6778********************7777777766555555565654422332444566666667776655000055666765422799*********** PP

                 HHHHHHHHHHTT-EEEEEEEE--HHHHHHHHHHT CS
       KTI12  86 RYeLyciakaakttlcvvyvvapldvlvkwneer 119
                 R+ L  +  + +++   +  +++  ++++ n  r
  EEA18879.1 156 RRSLAKEFAKQNIETLFIESMCDDPKIIEENVRR 189
                 ****999999999999999999977666666443 PP

>> APS_kinase  Adenylylsulphate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.1   0.00012      0.43       4     106 ..      56     172 ..      52     189 .. 0.62

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00012
                 EEEEESSTTSSHHHHHHHHHHHHHHTT--EEEE.EHHHHTT......TTTTT--SSHHH......HHHHHHHHH.HHHHHHH.HTT-EEEEE----SHH CS
  APS_kinase   4 vvwltGlsgsGKstianalekkLvekgisvylL.dGdnvRh......gLnkdLgfseed......Rkenirrva.evaklla.daglivlvafisPyre 87 
                 v+   Gl + GK+ i++al+++L+  g+++ +   Gd  R       ++  d  f ++       R++ +++    +a+ l+ ++g+i++  ++ P ++
  EEA18879.1  56 VIITVGLPARGKTHISVALARYLRWLGVKTRIFhLGDYRRAtigpgqDMPDDYFFVNASassvllRQKIVKKCRdDIAHFLSeENGQIAIYDAVNPIAA 154
                 56667**********************888765269988861111113445555666652222224444444322467766524688999999999888 PP

                 HHHHHHHHHHCHTEEEEEE CS
  APS_kinase  88 eReaarelleealkfievf 106
                  R++  + ++++ ++ ++f
  EEA18879.1 155 GRRSLAKEFAKQ-NIETLF 172
                 776654444433.333333 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   7.5e-05      0.27       1      39 [.      56      99 ..      56     201 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 7.5e-05
      AAA_33  1 lvllvGlpGsGKstlaerllkklgavllssdt.....lrrrlfg 39
                ++++vGlp+ GK++ +  l++ l +  + + +     +rr+  g
  EEA18879.1 56 VIITVGLPARGKTHISVALARYLRWLGVKTRIfhlgdYRRATIG 99
                89*****************9998876666665444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (534 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       686  (0.038262); expected 358.6 (0.02)
Passed bias filter:                      578  (0.0322383); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.45
# Mc/sec: 3581.34
//
Query:       EEA18880.1  [L=117]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      4e-34  116.9   0.0    4.7e-34  116.6   0.0    1.1  1  Urm1      Urm1 (Ubiquitin related modifier)
  ------ inclusion threshold ------
      0.031   14.9   0.0      0.039   14.6   0.0    1.2  1  ThiS      ThiS family


Domain annotation for each model (and alignments):
>> Urm1  Urm1 (Ubiquitin related modifier)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.6   0.0   5.3e-38   4.7e-34       2      96 .]      19     117 .]      18     117 .] 0.96

  Alignments for each domain:
  == domain 1  score: 116.6 bits;  conditional E-value: 5.3e-38
                 EEEEEETTCGGGCTT-SEEEEEE-...SSSSS-BHHHHHHHHCCCC-SS.GHHHCBSTTSB-TTEEEEETTCEHHHCTCCCSB--TTEEEEEEETTT-- CS
        Urm1   2 veleflgGlelllekkkkhkvele...ieseevnleeliayikknlike.rkevFlekdkvrPGilvLindaDwellgekdyelkdkDkivFistlhGG 96 
                 +++ef+gGle+l+++++kh+++++   +e ++ +++ li+y+++ l+++ rke+F+ +d+vrPGilvLindaDwel+ge+ ye++ +D+i+F+stlhGG
  EEA18880.1  19 ISVEFTGGLEMLFANERKHNLTIPaktSEGKQPTIAWLIQYLVEILMQDtRKELFILDDHVRPGILVLINDADWELEGEEAYEIQPRDNILFVSTLHGG 117
                 78*********************9776778899****************999**********************************************9 PP

>> ThiS  ThiS family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.0   4.4e-06     0.039      14      77 .]      43     117 .]      29     117 .] 0.79

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 4.4e-06
                 EEEEESSTSBHHHHHHHHHHHTCHHG..........TTTTEEEEETTEEEGC.CTTTSB--TTCEEEEEESTTC- CS
        ThiS  14 eelelaegstvaelleaLgerypela..........lerrvavavNgeivpr.lwldtelkdgDevailppVaGG 77 
                  ++ ++ + t+a l++ L e   + +           ++++ v++N+ + +   ++ +e+++ D + ++    GG
  EEA18880.1  43 AKTSEGKQPTIAWLIQYLVEILMQDTrkelfilddhVRPGILVLINDADWELeGEEAYEIQPRDNILFVSTLHGG 117
                 45666778888888888855554444556679999999**************66***************999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (117 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       304  (0.0169558); expected 358.6 (0.02)
Passed bias filter:                      293  (0.0163422); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.32s 00:00:00.76 Elapsed: 00:00:00.49
# Mc/sec: 715.37
//
Query:       EEA18881.1  [L=805]
Description: RNA polymerase II Elongator subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.3e-34  116.0  29.8    1.6e-06   28.8   0.2   11.7 12  WD40         WD domain, G-beta repeat
    3.3e-14   52.9   1.8      0.028   14.7   0.0    6.5  6  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.1         2   1.8e+04      25      37 ..      29      40 ..      19      40 .. 0.67
   2 !   15.8   0.1   2.1e-06     0.019       7      37 ..      52      87 ..      46      88 .. 0.68
   3 !   28.8   0.2   1.7e-10   1.6e-06       2      37 ..      97     133 ..      96     134 .. 0.93
   4 !   17.2   0.1   7.5e-07    0.0068       6      38 .]     206     241 ..     202     241 .. 0.83
   5 !   12.2   0.0   2.9e-05      0.26       8      37 ..     290     322 ..     280     323 .. 0.85
   6 ?   -0.5   0.6       0.3   2.7e+03      16      37 ..     360     380 ..     344     380 .. 0.73
   7 !   15.0   0.1   3.8e-06     0.034       7      37 ..     395     426 ..     389     426 .. 0.84
   8 ?    0.1   0.0       0.2   1.8e+03      12      38 .]     449     474 ..     438     474 .. 0.75
   9 !    6.9   0.1    0.0014        13       7      30 ..     563     587 ..     557     600 .. 0.74
  10 !   14.3   0.0   6.5e-06     0.058       6      33 ..     610     638 ..     605     643 .. 0.83
  11 !    8.8   0.0   0.00035       3.1       9      37 ..     661     693 ..     651     694 .. 0.67
  12 !    7.4   0.0   0.00097       8.7      12      37 ..     766     799 ..     752     800 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 2
                EEEEETTSEEEEE CS
        WD40 25 lasGsdDgtvriW 37
                la G  D++v +W
  EEA18881.1 29 LAYGA-DNNVALW 40
                33356.9999999 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 2.1e-06
                EESS.SSEEEEE...EETTSSE....EEEEETTSEEEEE CS
        WD40  7 ltGH.ssvtsla...fspdgaw....lasGsdDgtvriW 37
                l GH + v++++        +     l++Gs D+++r+W
  EEA18881.1 52 LVGHrDKVSAVRflaH---PKSkrslLITGSVDHSIRVW 87
                4699766777753322...222445578*********** PP

  == domain 3  score: 28.8 bits;  conditional E-value: 1.7e-10
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 
                 +c+ +ltGH + v+ +a + +++ +asG  Dgtvr+W
  EEA18881.1  97 TCVCELTGHtGTVNTIAIDNSSNVFASGAADGTVRVW 133
                 6999*****777****************99******* PP

  == domain 4  score: 17.2 bits;  conditional E-value: 7.5e-07
                 EEESS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS
        WD40   6 tltGH.ssvtsla...fspdgawlasGsdDgtvriWd 38 
                 +l+GH  +v+sl    f+ d  + as+s D+ +r+W+
  EEA18881.1 206 KLSGHeAWVRSLTfrkFDNDYIL-ASASQDKYIRLWK 241
                 689**988****98766666666.789*********6 PP

  == domain 5  score: 12.2 bits;  conditional E-value: 2.9e-05
                 ESS.SSEEEEEEETTSSE..EEEEETTSEEEEE CS
        WD40   8 tGH.ssvtslafspdgaw..lasGsdDgtvriW 37 
                  GH ++++ + +sp+     l+s+s D+++ iW
  EEA18881.1 290 LGHeDWIYTVNWSPSTEKaqLLSASADNSLTIW 322
                 49*888****9999999999889999******* PP

  == domain 6  score: -0.5 bits;  conditional E-value: 0.3
                 EEEETTSSEEEEEETTSEEEEE CS
        WD40  16 lafspdgawlasGsdDgtvriW 37 
                 l +spdg+ ++s ++ g+ r+W
  EEA18881.1 360 L-WSPDGNEVVSLTRTGSWRVW 380
                 4.9*****99864566666666 PP

  == domain 7  score: 15.0 bits;  conditional E-value: 3.8e-06
                 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 
                  +GH  sv++++++  ga+l+s s D+t r++
  EEA18881.1 395 VSGHiRSVNDIQWDAQGAYLLSTSSDQTSRLY 426
                 48**999************987666***9986 PP

  == domain 8  score: 0.1 bits;  conditional E-value: 0.2
                 SEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  12 svtslafspdgawlasGsdDgtvriWd 38 
                 + +++++    +++ sG d + +r+++
  EEA18881.1 449 DLNCIDTLGPARFV-SGADEKLLRVFN 474
                 48899777777775.899999999986 PP

  == domain 9  score: 6.9 bits;  conditional E-value: 0.0014
                 EESSSS.EEEEEEETTSSEEEEEET CS
        WD40   7 ltGHss.vtslafspdgawlasGsd 30 
                 l GH+  ++++a+s+d +++a++++
  EEA18881.1 563 LYGHGYeISAVAVSHDRSLIATACK 587
                 679*446*************98764 PP

  == domain 10  score: 14.3 bits;  conditional E-value: 6.5e-06
                 EEESSSS..EEEEEEETTSSEEEEEETTSE CS
        WD40   6 tltGHss..vtslafspdgawlasGsdDgt 33 
                 +l +H s  +tsl+fsp+ ++l+s ++D+ 
  EEA18881.1 610 SLIAH-SltITSLCFSPSDKYLLSVGRDRQ 638
                 57799.446**************9899986 PP

  == domain 11  score: 8.8 bits;  conditional E-value: 0.00035
                 SSSS.EEEEEEETTSSE.........EEEEETTSEEEEE CS
        WD40   9 GHss.vtslafspdgaw.........lasGsdDgtvriW 37 
                 +Hs  + + a      w         +a++++D+ v+iW
  EEA18881.1 661 AHSRmILDAA------WapslgqqavFATAGRDKCVKIW 693
                 5644666663......3333333665899999******* PP

  == domain 12  score: 7.4 bits;  conditional E-value: 0.00097
                 SEEEEE.......EETTSSEE.EEEETTSEEEEE CS
        WD40  12 svtsla.......fspdgawl.asGsdDgtvriW 37 
                 s+t l        +s+dg+ l a +s+D +vri+
  EEA18881.1 766 SITQLTwrpgqssTSKDGNVLlAVASEDSSVRIY 799
                 477776666666678888886256799******8 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.0   0.0    0.0067        60      35      65 ..     103     133 ..      82     161 .. 0.79
   2 ?   -2.7   0.0      0.83   7.5e+03      52      71 ..     176     195 ..     173     202 .. 0.85
   3 !   12.5   0.0   1.6e-05      0.14      30      82 ..     203     257 ..     198     284 .. 0.87
   4 !    6.4   0.2    0.0013        11      19      65 ..     369     426 ..     361     432 .. 0.81
   5 !    7.5   0.0   0.00056         5       7      72 ..     579     649 ..     573     672 .. 0.78
   6 !   14.7   0.0   3.1e-06     0.028       9      68 ..     729     802 ..     725     804 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.0067
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdgevrll 65 
                  +++ ++v+ +a  ++ +++a + +dg+vr+ 
   EEA18881.1 103 TGHTGTVNTIAIDNSSNVFASGAADGTVRVW 133
                  5678899999999**************9985 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 0.83
  ANAPC4_WD40  52 lLavaysdgevrlldaesgk 71 
                  ++av+   ++v++++a++++
   EEA18881.1 176 VMAVGGTINHVHVFSAQDTT 195
                  78999999999999998876 PP

  == domain 3  score: 12.5 bits;  conditional E-value: 1.6e-05
  ANAPC4_WD40  30 wtleedkedsevrsLaWkp..dgklLavaysdgevrlldaesgkvvhslsvksek 82 
                  w+++ ++++  vrsL +++  ++ +La a +d  +rl +++ g++v +++ ++++
   EEA18881.1 203 WNAKLSGHEAWVRSLTFRKfdNDYILASASQDKYIRLWKVHRGEIVPAIPKDEDE 257
                  66666788899******9744788**********************999988876 PP

  == domain 4  score: 6.4 bits;  conditional E-value: 0.0013
  ANAPC4_WD40  19 llvfRlngqrvwtl...........eedkedsevrsLaWkpdgklLavaysdgevrll 65 
                  + + R+   rvw               +++ ++v++++W  +g  L    sd + rl+
   EEA18881.1 369 VSLTRTGSWRVWAHdeesdiwqqrlGVSGHIRSVNDIQWDAQGAYLLSTSSDQTSRLY 426
                  66777777777777777777766776778889999*****************999987 PP

  == domain 5  score: 7.5 bits;  conditional E-value: 0.00056
  ANAPC4_WD40   7 mDLiAlatedgel..lvfRlngqrvwtl...eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkv 72 
                  + LiA a + +++  +v Rl   + w     +  +++ +++sL+++p++k L  +  d +  +++  ++++
   EEA18881.1 579 RSLIATACKASSIdhAVIRLYDTKNWREikpSLIAHSLTITSLCFSPSDKYLLSVGRDRQWAIFKRDDEEL 649
                  56888888888774457888666666665555678999*****************9999999998777665 PP

  == domain 6  score: 14.7 bits;  conditional E-value: 3.1e-06
  ANAPC4_WD40   9 LiAlatedgellvfRlng.....qrvwtl.eedkedsevrsLaWkp.......dgk.lLavaysdgevrlldae 68 
                  L+A++ e+g++ v+ +       q+++tl  ++++++++++L W+p       dg+ lLava +d++vr++ + 
   EEA18881.1 729 LLAVGEETGQISVHKVAVdsleaQELVTLdVSSTPSKSITQLTWRPgqsstskDGNvLLAVASEDSSVRIYRVA 802
                  899*******99999876556668888887678999********9755555556773579**********9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (805 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       403  (0.0224776); expected 358.6 (0.02)
Passed bias filter:                      357  (0.0199119); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.26s 00:00:00.93 Elapsed: 00:00:00.45
# Mc/sec: 5387.82
//
Query:       EEA18882.1  [L=277]
Description: ABC transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.8e-16   59.0   0.4    3.1e-15   56.9   0.4    2.0  1  ABC_tran     ABC transporter
    2.3e-10   40.8   3.6    8.4e-05   22.5   0.8    2.1  2  AAA_21       AAA domain, putative AbiEii toxin, Type IV TA sy
      0.001   18.8   1.5     0.0024   17.6   1.5    1.6  1  AAA_29       P-loop containing region of AAA domain
     0.0019   17.7   0.0       0.79    9.1   0.0    2.1  2  SMC_N        RecF/RecN/SMC N terminal domain
     0.0019   18.0   0.0     0.0027   17.5   0.0    1.2  1  PduV-EutP    Ethanolamine utilisation - propanediol utilisati
     0.0022   15.6   0.5     0.0031   15.1   0.5    1.1  1  DUF3584      Protein of unknown function (DUF3584)
     0.0092   16.5   0.4      0.015   15.8   0.4    1.2  1  AAA_23       AAA domain
  ------ inclusion threshold ------
      0.026   14.2   0.2      0.037   13.7   0.2    1.2  1  AAA_15       AAA ATPase domain
      0.028   14.3   0.3      0.044   13.7   0.3    1.3  1  RsgA_GTPase  RsgA GTPase
      0.037   13.6   0.3      0.066   12.8   0.3    1.4  1  AAA_25       AAA domain
      0.044   14.0   0.8      0.081   13.2   0.8    1.4  1  AAA_28       AAA domain
       0.06   13.7   0.1       0.12   12.7   0.1    1.5  1  AAA_16       AAA ATPase domain
      0.099   11.4   0.2       0.16   10.8   0.2    1.2  1  DLIC         Dynein light intermediate chain (DLIC)
       0.12   11.0   0.1       0.16   10.6   0.1    1.1  1  AAA_13       AAA domain
       0.13   11.7   0.1       0.24   10.8   0.1    1.4  1  Arf          ADP-ribosylation factor family
       0.13   12.5   0.1       0.36   11.1   0.1    1.7  1  AAA_22       AAA domain
       0.16   12.0   0.4       0.87    9.6   0.1    2.0  2  AAA_5        AAA domain (dynein-related subfamily)
       0.17   12.3   0.2       0.83   10.1   0.2    2.2  1  AAA          ATPase family associated with various cellular a
       0.17   12.0   0.0       0.24   11.5   0.0    1.4  1  MMR_HSR1     50S ribosome-binding GTPase
       0.17   12.1   0.0       0.33   11.2   0.0    1.5  1  Roc          Ras of Complex, Roc, domain of DAPkinase
       0.26   11.0   0.1       0.43   10.3   0.1    1.4  1  AAA_24       AAA domain
       0.28   10.8   0.1       0.44   10.2   0.1    1.2  1  SRP54        SRP54-type protein, GTPase domain


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.9   0.4   3.8e-18   3.1e-15       1     136 [.      21     157 ..      21     158 .. 0.75

  Alignments for each domain:
  == domain 1  score: 56.9 bits;  conditional E-value: 3.8e-18
                 EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGG........B-HHHCCHCEEEE-SS--S-TTSBHHHH............ CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxxxxxxxxxxxxxx............ RF
    ABC_tran   1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlke........qeleslrkeigvlpqepqlfpeltvren............ 79 
                 lk v l+l  g+++ ++G nGaGK+tLl+ll+g+      +i + gkd  +           e++ ++i                              
  EEA18882.1  21 LKGVGLSLPSGSRTLLIGANGAGKTTLLRLLSGKKLAPTNTIAIGGKDPFKdslegvtyLGVEWVLNSIVRT--------------Didvptllasvgg 105
                 78999****************************************776655244444333333333333333..............2223333444444 PP

                 .HHHTCHHHHHHHSTTGGTTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 .xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  80 .esdeeiekalsklglkelkdtvvksspssLSgGqkqrvalarallkkpkllllDEpt 136
                  ++ e+ +++++ l+++   + ++    + +S G+++rv+la+ ll+  ++lllDE t
  EEA18882.1 106 nAYPERRDELIDILDIDL--NWRM----HAVSDGERRRVQLAMGLLRPWQILLLDEIT 157
                 377778888888887666..5566....99**************************87 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5   0.8     1e-07   8.4e-05       2      21 ..      34      53 ..      33      95 .. 0.71
   2 !   19.1   0.1   1.2e-06   0.00095     229     297 ..     122     188 ..     106     193 .. 0.90

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 1e-07
      AAA_21  2 nvliGpNgsGKSnLLdaldl 21
                ++liG+Ng+GK++LL++l++
  EEA18882.1 34 TLLIGANGAGKTTLLRLLSG 53
                79****************75 PP

  == domain 2  score: 19.1 bits;  conditional E-value: 1.2e-06
      AAA_21 229 gqelparelSdGtkrllalltallralkkgsllliDEpEngLHPkllrrllellkelsr.ngaQviltTH 297
                 + ++ ++ +SdG +r   l+  llr      +ll+DE+   L+      +l +lk++++ +   ++ +TH
  EEA18882.1 122 DLNWRMHAVSDGERRRVQLAMGLLRPW---QILLLDEITVDLDLLSRYNFLSFLKRETEtRECTIVYATH 188
                 56789999*****************99...9***********************8777779********* PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   1.5     3e-06    0.0024      22      58 ..      30      63 ..      20      66 .. 0.80

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 3e-06
      AAA_29 22 kg.atlltGpsGsGKSTllDAiqalLvpakkvrfNkaa 58
                +g  tll+G++G+GK+Tll     lL ++k +  N  a
  EEA18882.1 30 SGsRTLLIGANGAGKTTLL----RLLSGKKLAPTNTIA 63
                4558**************9....788887777777665 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.6   0.0    0.0058       4.7      25      41 ..      32      48 ..      26      52 .. 0.85
   2 !    9.1   0.0   0.00097      0.79     145     191 ..     138     180 ..     104     196 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.0058
                SEEEEEESTTSSHHHHH CS
                xxxxxxxxxxxxxxxxx RF
       SMC_N 25 sftaivGpNGSGKsnll 41
                s t ++G+NG+GK+ ll
  EEA18882.1 32 SRTLLIGANGAGKTTLL 48
                56899*********987 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.00097
                 HHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 145 valaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQ 191
                 v     +A+   +p  + llDei   LD   + ++ ++lk+++++  
  EEA18882.1 138 VQ----LAMGLLRPWQILLLDEITVDLDLLSRYNFLSFLKRETETRE 180
                 44....4566799***************************8887644 PP

>> PduV-EutP  Ethanolamine utilisation - propanediol utilisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   0.0   3.3e-06    0.0027       3      38 ..      33      68 ..      31      97 .. 0.89

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 3.3e-06
   PduV-EutP  3 killiGkvgsGKttLtqalkgeelkYkktqaiefsd 38
                + lliG+ g+GKttL + l+g++l  + t ai  +d
  EEA18882.1 33 RTLLIGANGAGKTTLLRLLSGKKLAPTNTIAIGGKD 68
                789*********************999998886655 PP

>> DUF3584  Protein of unknown function (DUF3584)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.5   3.8e-06    0.0031      16      37 ..      30      51 ..      18      52 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 3.8e-06
     DUF3584 16 ldghtnieGtNaaGKTtLlrLi 37
                   +t + G+N+aGKTtLlrL+
  EEA18882.1 30 SGSRTLLIGANGAGKTTLLRLL 51
                556899***************7 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.4   1.9e-05     0.015      22      39 ..      34      51 ..      22      53 .. 0.90

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 1.9e-05
      AAA_23 22 tlItGpNGaGKTTildAi 39
                tl++G NGaGKTT+l+ +
  EEA18882.1 34 TLLIGANGAGKTTLLRLL 51
                89************9865 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.2   4.6e-05     0.037      26      43 ..      34      51 ..      21      71 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 4.6e-05
      AAA_15 26 tvliGkNnsGKSsileal 43
                t+liG+N++GK+++l++l
  EEA18882.1 34 TLLIGANGAGKTTLLRLL 51
                9**************998 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.3   5.4e-05     0.044      99     130 ..      30      62 ..       4      67 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 5.4e-05
                  T.SEEEEECSTTSSHHHHHHHHCTT-----S-- CS
  RsgA_GTPase  99 d.ktsvlvGqSGvGKStLinallpelelktgev 130
                  + + ++l+G  G+GK+tL+  l +++ + t+ +
   EEA18882.1  30 SgSRTLLIGANGAGKTTLLRLLSGKKLAPTNTI 62 
                  437899*****************9987777766 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.3   8.1e-05     0.066      30      51 ..      28      49 ..      22      72 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 8.1e-05
      AAA_25 30 lpagelallaGapgtGKttlal 51
                lp g+ +ll+Ga g+GKttl+ 
  EEA18882.1 28 LPSGSRTLLIGANGAGKTTLLR 49
                799****************985 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.8    0.0001     0.081       3      22 ..      35      54 ..      33      67 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 0.0001
      AAA_28  3 vitGgestGKTtlleaLaar 22
                 ++G+ ++GKTtll+ L+ +
  EEA18882.1 35 LLIGANGAGKTTLLRLLSGK 54
                79*************99854 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.1   0.00015      0.12      24      45 ..      31      52 ..      25      92 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 0.00015
      AAA_16 24 pelvllsGesGvGKsslvrell 45
                ++ +ll+G+ G GK++l+r l 
  EEA18882.1 31 GSRTLLIGANGAGKTTLLRLLS 52
                46789*************9986 PP

>> DLIC  Dynein light intermediate chain (DLIC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.2    0.0002      0.16      22      47 ..      28      53 ..      24      59 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.0002
        DLIC 22 lPsgksvlvlGedgsGkttliaklqG 47
                lPsg   l++G +g+Gkttl+  l G
  EEA18882.1 28 LPSGSRTLLIGANGAGKTTLLRLLSG 53
                9*******************998877 PP

>> AAA_13  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.1    0.0002      0.16      20      40 ..      35      55 ..      29      71 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.0002
      AAA_13 20 liYGwNGaGKTtLSrllrsle 40
                l+ G+NGaGKTtL rll+  +
  EEA18882.1 35 LLIGANGAGKTTLLRLLSGKK 55
                567*************99754 PP

>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.1    0.0003      0.24      15      40 ..      32      57 ..      25      65 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.0003
                EEEEEEESTTSSHHHHHHHHHHSSCE CS
         Arf 15 lrilllGLDnaGKtTilkklkleelv 40
                 r ll+G  +aGKtT+l  l+ ++l+
  EEA18882.1 32 SRTLLIGANGAGKTTLLRLLSGKKLA 57
                589**************999988765 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.1   0.00044      0.36       8      27 ..      34      53 ..      30      76 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00044
      AAA_22  8 lvvtGesGtGKTtllrrlle 27
                ++++G  G+GKTtllr l  
  EEA18882.1 34 TLLIGANGAGKTTLLRLLSG 53
                689*************9865 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.1    0.0011      0.87       3      23 ..      35      55 ..      33      69 .. 0.81
   2 ?   -0.1   0.0         1   8.3e+02      43      75 ..     125     157 ..     112     174 .. 0.69

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0011
                EEE--SSSSHHHHHHHGGGGB CS
       AAA_5  3 lLvGppGtgKselaerlaaal 23
                lL+G+ G gK++l + l+   
  EEA18882.1 35 LLIGANGAGKTTLLRLLSGKK 55
                9***************99765 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 1
                 --B--.........--------G-SEEEEESGG CS
       AAA_5  43 grreikngttslvdsplvraaregeilvlDEve 75 
                 +r++  +++++++ + ++   r  +il+lDE++
  EEA18882.1 125 WRMHAVSDGERRRVQLAMGLLRPWQILLLDEIT 157
                 444433455555555555577888999999997 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.2     0.001      0.83       2      33 ..      35      68 ..      34     196 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.001
                EEESSTTSSHHHHHHHHHHH..HTHEEEEEETTT CS
         AAA  2 llyGppGtGKTllakavake..lgvefleisgse 33
                ll+G  G GKT+l + +  +  + ++ + i g++
  EEA18882.1 35 LLIGANGAGKTTLLRLLSGKklAPTNTIAIGGKD 68
                89*************9988743234445554444 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   0.00029      0.24       3      27 ..      35      60 ..      33     117 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00029
                EEEESTTSSHHHHHHHHHTS.TEEES CS
    MMR_HSR1  3 aivGrpNvGKStLinaltge.kaivs 27
                +++G   +GK+tL++ l+g+  a ++
  EEA18882.1 35 LLIGANGAGKTTLLRLLSGKkLAPTN 60
                79****************98334443 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0    0.0004      0.33       2      33 ..      34      65 ..      33      80 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.0004
                EEEESSTTSSHHHHHHCHCT-CCC-EEETTTT CS
         Roc  2 vvlvGdsgvGKtsllkrfvedkfsekekstig 33
                 +l+G +g+GKt+ll+ +  +k  ++++  ig
  EEA18882.1 34 TLLIGANGAGKTTLLRLLSGKKLAPTNTIAIG 65
                589*************9999999888766665 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.1   0.00053      0.43       3      23 ..      32      53 ..      30      85 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00053
      AAA_24  3 lkiliyGpsgiGKTtlakel.g 23
                 + l++G +g+GKTtl++ l g
  EEA18882.1 32 SRTLLIGANGAGKTTLLRLLsG 53
                5789*************99852 PP

>> SRP54  SRP54-type protein, GTPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.1   0.00054      0.44       4      40 ..      34      70 ..      32      74 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00054
                EEEEESTTSSHHHHHHHHHHHHHHTTS-EEEEEESTS CS
       SRP54  4 illvGlqGaGKTttlaKLaallkkegkkvllvaaDtf 40
                +ll+G +GaGKTt l  L+ +  +  +++++   D f
  EEA18882.1 34 TLLIGANGAGKTTLLRLLSGKKLAPTNTIAIGGKDPF 70
                69***********998887776666666666666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (277 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       302  (0.0168442); expected 358.6 (0.02)
Passed bias filter:                      299  (0.0166769); expected 358.6 (0.02)
Passed Vit filter:                        87  (0.00485247); expected 17.9 (0.001)
Passed Fwd filter:                        22  (0.00122706); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              22  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 1890.16
//
Query:       EEA18883.1  [L=463]
Description: tRNA isopentenyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.5e-64  215.3   0.3    1.4e-63  214.8   0.3    1.2  1  IPPT            IPP transferase
    6.9e-05   23.0   0.6      0.014   15.6   0.1    3.5  2  AAA_33          AAA domain
    0.00023   21.4   0.3     0.0005   20.4   0.3    1.6  1  zf-met          Zinc-finger of C2H2 type
    0.00073   19.0   0.0     0.0018   17.7   0.0    1.6  1  IPT             Isopentenyl transferase
     0.0015   19.0   0.0     0.0062   16.9   0.0    2.1  2  AAA_16          AAA ATPase domain
     0.0028   18.2   0.4       0.83   10.2   0.0    2.9  2  AAA_18          AAA domain
  ------ inclusion threshold ------
      0.016   15.5   0.1      0.033   14.5   0.1    1.6  1  zf-C2H2_jaz     Zinc-finger double-stranded RNA-binding
      0.016   15.5   0.2      0.031   14.6   0.2    1.4  1  zf-C2H2_2       C2H2 type zinc-finger (2 copies)
      0.028   14.7   0.1       0.26   11.5   0.0    2.5  2  AAA_22          AAA domain
      0.046   13.5   0.0        0.1   12.4   0.0    1.5  1  DUF3449         Domain of unknown function (DUF3449)
       0.17   11.6   0.0       0.31   10.7   0.0    1.6  1  Cytidylate_kin  Cytidylate kinase
       0.18   12.3   0.0       0.42   11.0   0.0    1.7  1  AAA             ATPase family associated with various cellula


Domain annotation for each model (and alignments):
>> IPPT  IPP transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  214.8   0.3   9.2e-67   1.4e-63       1     224 [.      37     327 ..      37     331 .. 0.81

  Alignments for each domain:
  == domain 1  score: 214.8 bits;  conditional E-value: 9.2e-67
                 TTBTT-HTTTT---HHHHTTS-EESSS-B-TTS.---HHHHHHHHHHHHHHHHHTT-EEEEEES-HHHHHHHHCTG.-S-..........-B--H..HH CS
        IPPT   1 qvYrgmdIgTakptaeeragvphhlidildpde.eysvadFqkdalkaieeilargkipilvGGTglYikallegl.del..........peade..el 85 
                 q+Yrg++I+T+k+  +er+gvphhlid++ ++e ++ +++F+k++l++i++i++rgkip+lvGGT +Y++a+l  + d l          ++  +  ++
  EEA18883.1  37 QLYRGLPIITNKIPMHEREGVPHHLIDFIGLEEeSWRIGQFRKECLRVIQDIHSRGKIPVLVGGTSYYVQAVL--FnDALvgegvedvlsNN--SgrQV 131
                 89*****************************9989*************************************9..54444676665544311..12244 PP

                 HHHH.HHH..HHHSHHHHHHHHHHHC-HHHHTTS-TT-HHHHHHHHHHHHHHSS-HH...........................ECEEEEEECSHHHHH CS
        IPPT  86 rael.eee..aeeeglealheelkevdpeaaakihpndrqRiiRalevyeetgkpls...........................ellviglesdreely 154
                 ++e  +ee  + ++  e ++e+l+evdp +a+++h n+ ++i R+le+y etg+p+s                           ++lv++++++re+ly
  EEA18883.1 132 NKERtSEEwaILDAPVETMMEKLREVDPIMANRWHINEGRKIRRSLEIYLETGRPASeiyeeqmrqrqaaidnkegittgqlrfPTLVFWVHAEREKLY 230
                 333212222123334777***************************************88888888777777777777766666545*****99****** PP

                 HHHHHHHHHHHHTTHHHHHHHHHH............CC....CCSTTSHHHHHHHTT.........SS-..HHHHHHHHHHHHHHHHHHHHHHHHTT CS
        IPPT 155 eridkRvdemleaGlleEveklla............ka....lqaigykelleyleg.........els..leeaieklkaatrqyaKrQltWfrkk 224
                  r++ Rvd+m e+Gl++E+++l +             +    + +igyke+ +y++          el+   e+++e +k++trqy  rQ++W+rkk
  EEA18883.1 231 GRLESRVDTMAEQGLIAEAHSLSEyaleqeaqgnpiDVsrgiWVSIGYKEMEPYFTAlragnlnekELEtlKESCLESVKTSTRQYSTRQVQWIRKK 327
                 ***********************8777777766655105566*************6333333443355334578*********************97 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.1   9.1e-06     0.014       1      33 [.       4     104 ..       4     255 .. 0.59
   2 ?    1.5   0.1       0.2     3e+02      47     137 ..     316     409 ..     288     412 .. 0.75

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 9.1e-06
      AAA_33   1 lvllvGlpGsGKstlaerllkklgavllssdt................................................................... 32 
                 l+ +vG+ G+GKs la  ++k+  +++++ d+                                                                   
  EEA18883.1   4 LITVVGATGTGKSKLAVDIAKQFNGEVINGDAmqlyrglpiitnkipmheregvphhlidfigleeeswrigqfrkeclrviqdihsrgkipvlvggts 102
                 6889***************************97777777776666666666666666666666666666666666655555555555555555555555 PP

      AAA_33  33 .l 33 
                  +
  EEA18883.1 103 yY 104
                 51 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.2
      AAA_33  47 dytrvldrlyqilnelarkalsagrnvildat...nlsrrerarflklarrlgvpvrivvvetdeetlkeRlakRaangddrsevpeealdrqk 137
                 ++tr  +++++ l   +++  + ++ ++ld t    ++ +  a + ++a+ + +++++   ++  + ++e l +R++n ++ + +p ++l++++
  EEA18883.1 316 YSTRQVQWIRKKLWTALADIGATNQLFVLDTTdpgAWDSCVAAPMERIAQAFLCNETLPEPKSLSQWAEETLTEREHNYTKVTVPPAQTLKQMT 409
                 4455556666666555555666666688877777788888889999999999999999999999999999999999999888888899998885 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.3   3.3e-07    0.0005       2      21 ..     409     428 ..     408     432 .. 0.91

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 3.3e-07
      zf-met   2 yCelCnvtfnsesqlksHlq 21 
                 +Ce+Cn+t+ ++ q++ H++
  EEA18883.1 409 TCEICNKTMMGQEQWDIHMR 428
                 6******************8 PP

>> IPT  Isopentenyl transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0   1.2e-06    0.0018       5      41 ..       6      42 ..       2      57 .. 0.90

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 1.2e-06
         IPT  5 lifGatttGKtaeaiklaketgapvivlDRvqcysel 41
                 ++Gat+tGK++ a+ +ak+    vi  D +q y  l
  EEA18883.1  6 TVVGATGTGKSKLAVDIAKQFNGEVINGDAMQLYRGL 42
                689*****************************99876 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.0   4.2e-06    0.0062      25     106 ..       3      86 ..       1     161 [. 0.79
   2 ?   -1.2   0.0       1.5   2.3e+03      60     106 ..     352     391 ..     298     445 .. 0.68

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 4.2e-06
      AAA_16  25 elvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipy......salaqalareellrqlldeaesaeleawrekleeala 106
                 +l+ ++G+ G+GKs+l+  ++++++++   +++g++ ql +++p        +  +    ++l+  ++ e+es   +++r++++++++
  EEA18883.1   3 PLITVVGATGTGKSKLAVDIAKQFNGE---VINGDAMQLYRGLPIitnkipMHEREGV-PHHLIDFIGLEEESWRIGQFRKECLRVIQ 86 
                 5789*********************99...9********9998876555422355555.45788888888888888888777777666 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 1.5
      AAA_16  60 cdqlesaipysalaqalareellrqlldeaesaeleawrekleeala 106
                 +d++  a+p+  +aqa+    l+++ l e   ++l++w+e+ +++ +
  EEA18883.1 352 WDSC-VAAPMERIAQAF----LCNETLPE--PKSLSQWAEETLTERE 391
                 4444.445666666666....44444444..3446777776555544 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.2   0.0   0.00056      0.83       1      22 [.       5      26 ..       5      54 .. 0.83
   2 ?    5.0   0.1     0.022        33      96     119 ..     200     242 ..     119     253 .. 0.73

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00056
      AAA_18  1 IlltGtpGvGKttlakeLskrl 22
                I + G+ G+GK+ la  ++k  
  EEA18883.1  5 ITVVGATGTGKSKLAVDIAKQF 26
                899***************9985 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.022
      AAA_18  96 k...................vvLtaspeelleRlekRgyeeak 119
                                     ++++a+ e+l+ Rle R  + a+
  EEA18883.1 200 AaidnkegittgqlrfptlvFWVHAEREKLYGRLESRVDTMAE 242
                 2444445566666677777799***************987666 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.1   2.2e-05     0.033       4      22 ..     410     428 ..     407     433 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 2.2e-05
                  BTTTTBBBSSHHHHHCCTT CS
  zf-C2H2_jaz   4 CvlCdKyFksenaldnHlk 22 
                  C++C+K++  ++++d H++
   EEA18883.1 410 CEICNKTMMGQEQWDIHMR 428
                  *****************98 PP

>> zf-C2H2_2  C2H2 type zinc-finger (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.2   2.1e-05     0.031      46      82 ..     404     439 ..     374     449 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 2.1e-05
   zf-C2H2_2  46 kieekleClyCekefkslealreHmkkkgHckineee 82 
                 ++++ ++C +C+k+   +e+   Hm+  +H++  +  
  EEA18883.1 404 TLKQ-MTCEICNKTMMGQEQWDIHMRASSHRRALKAA 439
                 4555.9********99**************9975543 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   0.00018      0.26       7      30 ..       4      27 ..       2     102 .. 0.84
   2 ?   -0.3   0.0      0.78   1.2e+03      33      70 ..     383     422 ..     369     447 .. 0.67

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00018
      AAA_22  7 ilvvtGesGtGKTtllrrlleqld 30
                +++v+G +GtGK+ l+  +++q++
  EEA18883.1  4 LITVVGATGTGKSKLAVDIAKQFN 27
                799*************99999984 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.78
      AAA_22  33 akaee..erpevvfvtlpsstsskdllrellralglelka 70 
                 a+ +   ++  + +vt+p   ++k++  e+++++  +++ 
  EEA18883.1 383 AEETLteREHNYTKVTVPPAQTLKQMTCEICNKTMMGQEQ 422
                 3333343566666999999999999988898888766555 PP

>> DUF3449  Domain of unknown function (DUF3449)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   6.8e-05       0.1      88     121 ..     406     438 ..     402     446 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 6.8e-05
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
     DUF3449  88 keykCeiCgnavYkGrkaFekHFseerHaeglkc 121
                 k+ +CeiC n++ +G+++++ H +++ H   lk+
  EEA18883.1 406 KQMTCEIC-NKTMMGQEQWDIHMRASSHRRALKA 438
                 5679****.7788****************99986 PP

>> Cytidylate_kin  Cytidylate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00021      0.31       1      45 [.       5      49 ..       5     127 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00021
                    EEEE-STTSSHHHHHHHHHHHHT-EEEEHHHH..HHHHHHHHHHTT- CS
  Cytidylate_kin  1 iaiDGPagsGKssvaralaeklglkyldtgal..YRalalaalrrkv 45
                    i++ G +g+GKs +a  +a++++ ++++  a+  YR l  +   +k+
      EEA18883.1  5 ITVVGATGTGKSKLAVDIAKQFNGEVINGDAMqlYRGLPII--TNKI 49
                    78899**********************98876337755443..3445 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00028      0.42       2      35 ..       6      39 ..       5      97 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00028
                EEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCS CS
         AAA  2 llyGppGtGKTllakavakelgvefleisgsell 35
                 ++G  GtGK+ la  +ak+++ e+++ ++++l 
  EEA18883.1  6 TVVGATGTGKSKLAVDIAKQFNGEVINGDAMQLY 39
                589*******************999998888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (463 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       748  (0.0417201); expected 358.6 (0.02)
Passed bias filter:                      586  (0.0326845); expected 358.6 (0.02)
Passed Vit filter:                        90  (0.0050198); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.47
# Mc/sec: 2953.49
//
Query:       EEA18884.1  [L=355]
Description: Dhp1-interacting protein Din1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.3e-27   93.0   0.0    1.8e-26   92.1   0.0    1.5  1  RAI1      RAI1 like PD-(D/E)XK nuclease


Domain annotation for each model (and alignments):
>> RAI1  RAI1 like PD-(D/E)XK nuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.1   0.0   9.9e-31   1.8e-26       1      66 [.     205     270 ..     205     272 .. 0.98

  Alignments for each domain:
  == domain 1  score: 92.1 bits;  conditional E-value: 9.9e-31
                 E-EESS---TTCCSGGGEEEEEEEE---SHHHHHHHHHHHHHHHHHHHHHT--EEEEEEE-TTSBE CS
        RAI1   1 VDcvwdakpedtnksehyvELKTskkiknekqlekferKllkfWaQSfLlGiprIvvGfRdddgil 66 
                 VD++wd+kp  ++++ ++vELKT++++ n+k++ k+erKllkfWaQSfLlG+p+IvvGfRd+dg+l
  EEA18884.1 205 VDAIWDSKPVRKEDPINWVELKTTAELVNDKEKLKYERKLLKFWAQSFLLGVPKIVVGFRDRDGML 270
                 9***************************************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (355 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       493  (0.0274974); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.24s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 2548.52
//
Query:       EEA18885.1  [L=342]
Description: DUF410 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-87  293.2   0.0    2.5e-87  292.9   0.0    1.1  1  DUF410    Protein of unknown function (DUF410)


Domain annotation for each model (and alignments):
>> DUF410  Protein of unknown function (DUF410)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  292.9   0.0   1.4e-91   2.5e-87       1     255 []      38     312 ..      38     312 .. 0.95

  Alignments for each domain:
  == domain 1  score: 292.9 bits;  conditional E-value: 1.4e-91
      DUF410   1 qkkydeAidllyqgalellkakqy....gsgaDLalllv.evyekaevev...dee...skdrliellskfpaeeperkkfikaaikwSakkgekkaGd 88 
                 q++yd+A+++l+ ga++ll+a+ +    +sg+DLa++lv evy+kae+e+   d+e   +k+rliell++fp++ep+rk++i+++i+wS+k+g+ ++Gd
  EEA18885.1  38 QSNYDAAAEILTGGAKALLRAGSQqgasASGGDLAIMLVvEVYNKAEWEIipeDAEsrgRKKRLIELLREFPPDEPSRKRYITEMISWSSKFGPLERGD 136
                 689*****************987545559*******9999**********88744456688************************************** PP

      DUF410  89 peLhhllaklllkegeleeAerhlllgtddsaeelakllvewaeegeeseadlfiaRavLqylllgnvkaAnklldeflkkleskessll.......te 180
                 peLhh++++++++e+e ++Aerhl+lgt dsae+lakl +ew++++e ++a+++++RavL++ll+ n++ Ank+l  f+++l++++ sl+       ++
  EEA18885.1 137 PELHHAVGSVYAEENEPYDAERHLVLGTIDSAETLAKLEFEWYTSDEAHTAAIYASRAVLPFLLTANLRSANKALLIFTSRLSAANLSLAsqevsstSS 235
                 **************************************************************************************9988999998622 PP

      DUF410 181 ..rvfp.lpllnFlqlllltiqrkskelFkkLkekYkpslkrdpslkeylekIgelyFgikpprqqsnglqdmmssLl 255
                   r++p lpllnFl+lll+++qr+s++lF++L+++Y p++k+ + ++++l+ Ige+yF+ik prq +n+l dmm+s++
  EEA18885.1 236 dvRIYPsLPLLNFLSLLLIAVQRGSADLFRDLTRHYTPHIKEVSIWDDALATIGEMYFNIKIPRQ-GNPLLDMMGSMF 312
                 68**************************************************************9.9**********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       332  (0.0185175); expected 358.6 (0.02)
Passed bias filter:                      293  (0.0163422); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 2356.69
//
Query:       EEA18886.1  [L=190]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (190 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       652  (0.0363657); expected 358.6 (0.02)
Passed bias filter:                      387  (0.0215851); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.48
# Mc/sec: 1202.41
//
Query:       EEA18887.1  [L=486]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.6e-06   27.0   0.0     0.0055   16.1   0.0    2.3  2  His_Phos_2  Histidine phosphatase superfamily (branch 2)


Domain annotation for each model (and alignments):
>> His_Phos_2  Histidine phosphatase superfamily (branch 2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.9   0.0   4.8e-05      0.86       1     134 [.      83     221 ..      83     338 .. 0.76
   2 !   16.1   0.0     3e-07    0.0055     288     381 ..     361     440 ..     356     441 .. 0.85

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 4.8e-05
                 EEEEEEEEEE--SBB-SHHHHHHHHH.HHHHHHH.................HHCHHTGCCGGGGT..................--SSSTTS.B-HHHHH CS
  His_Phos_2   1 eLksvvvviRHGdRtPkqkvkksvts.piflsllkkhke........Klkqlktalekkghfpgtyrkv.........eveklqlilkwggelthaGrk 81 
                 eL  v ++ RH  RtP ++++  +++  ++++  + +                          +ty ++          v +  +++   +  t++G +
  EEA18887.1  83 ELVYVEIIHRHHKRTPYESNTFPMEKdTWDCNGTQLYHYgqpsagsqM-------------SANTYWQLeehspfdlfPVSAFPGTCVFPQ-ITRTGLQ 167
                 678899**************8777541466666643321233332221.............222444446666666645666666666666.******* PP

                 HHHHHHHHHHHHCH..TCCHTTSS--TTEEEEEESSHHHHHHHHHHHHHHCHCCC CS
  His_Phos_2  82 qaeelGrqfrqrYp..lgLlrlhltykdlkirassegRviaSAaafakGllgleg 134
                    ++G+ +++ Y+  l +l+++l +k +++r ++   + + A  ++ G++ +eg
  EEA18887.1 168 DSWQHGHDIYEVYHdlLRFLPDELDQKRMEFRVTNNVITSQVAGMVIGGMY-GEG 221
                 **************9999999999999999999998888888888888888.555 PP

  == domain 2  score: 16.1 bits;  conditional E-value: 3e-07
                 HHHHHHHHHHCTSSSEECCSCCCECS-SEEEEEE-HHHHHHHHHHCTTTTTBTTB.SSS.TTT..HCCCS-CT-EEEEEEEEE...TCTTT...EEEEE CS
  His_Phos_2 288 lllnpllkkilndlqrtreeatperhvrlrlyfthdshiysllnaLglpeelagedslaaldrlsaspelpymsqivfelyed...ssekk...fyvrl 380
                 +++ +l+++++++++       +++ v +r  ++hd  i  +l++L++ +                  ++ ++++ivfely++   ssek+   f+vr+
  EEA18887.1 361 VFIAELAQHLREQIKLFD----QTDRVLYRHNVAHDGSISWILSLLQIKQ----------------MVWPGMGAEIVFELYRRkttSSEKEegsFFVRV 439
                 567788999999998888....8999999*******************99................89999***********777744443467****9 PP

                 E CS
  His_Phos_2 381 l 381
                 l
  EEA18887.1 440 L 440
                 7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (486 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       441  (0.024597); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.31s 00:00:00.87 Elapsed: 00:00:00.49
# Mc/sec: 2983.13
//
Query:       EEA18888.1  [L=350]
Description: DNA replication factor C subunit Rfc4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.4e-24   84.4   0.0    1.5e-23   83.0   0.0    1.8  1  Rep_fac_C        Replication factor C C-terminal domain
    3.1e-12   46.6   0.0      9e-09   35.3   0.0    2.2  2  DNA_pol3_delta2  DNA polymerase III, delta subunit
    6.4e-11   42.8   0.0    1.1e-10   42.1   0.0    1.4  1  AAA              ATPase family associated with various cellul
    8.1e-07   29.1   0.0    1.4e-06   28.4   0.0    1.4  1  AAA_14           AAA domain
    1.6e-05   25.4   0.0    0.00055   20.4   0.0    2.2  2  AAA_16           AAA ATPase domain
    2.6e-05   24.1   0.0    4.1e-05   23.4   0.0    1.3  1  Viral_helicase1  Viral (Superfamily 1) RNA helicase
    3.9e-05   23.4   0.0    9.8e-05   22.1   0.0    1.7  1  RuvB_N           Holliday junction DNA helicase RuvB P-loop d
      4e-05   23.5   0.0    8.3e-05   22.5   0.0    1.5  1  AAA_3            ATPase family associated with various cellul
    0.00014   21.7   0.0    0.00022   21.0   0.0    1.2  1  DNA_pol3_delta   DNA polymerase III, delta subunit
    0.00031   21.0   0.0       0.47   10.7   0.1    2.4  2  AAA_22           AAA domain
      0.004   17.1   0.0     0.0068   16.3   0.0    1.3  1  Rad17            Rad17 P-loop domain
     0.0057   16.1   0.1      0.056   12.8   0.0    2.0  2  Mg_chelatase     Magnesium chelatase, subunit ChlI
     0.0081   15.9   0.0       0.32   10.7   0.0    2.2  2  AAA_24           AAA domain
  ------ inclusion threshold ------
      0.011   14.8   0.0      0.019   14.0   0.0    1.4  1  MeaB             Methylmalonyl Co-A mutase-associated GTPase 
      0.015   15.6   0.0      0.043   14.2   0.0    1.8  1  AAA_assoc_2      AAA C-terminal domain
      0.017   15.0   0.0      0.025   14.4   0.0    1.3  1  AAA_11           AAA domain
      0.017   15.4   0.1      0.062   13.6   0.1    2.0  1  AAA_19           AAA domain
      0.052   13.5   0.0       0.14   12.0   0.0    1.8  1  NTPase_1         NTPase
      0.057   12.8   0.0        2.2    7.7   0.0    2.3  2  TniB             Bacterial TniB protein
      0.078   12.5   0.0       0.36   10.4   0.0    2.1  2  AAA_25           AAA domain
        0.1   12.3   0.0        0.3   10.8   0.0    1.7  1  AAA_30           AAA domain
       0.11   11.9   0.0       0.18   11.3   0.0    1.4  1  KTI12            Chromatin associated protein KTI12
       0.13   12.1   0.1          5    6.9   0.0    2.4  2  DEAD             DEAD/DEAH box helicase


Domain annotation for each model (and alignments):
>> Rep_fac_C  Replication factor C C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.0   0.0   1.9e-26   1.5e-23       1      88 []     250     336 ..     250     336 .. 0.98

  Alignments for each domain:
  == domain 1  score: 83.0 bits;  conditional E-value: 1.9e-26
                 --HHHHHHHHHHHHHT-HHHHHHHHHHHHHHC---HHHHHHHHHHHGCCS..S-HHHHHHHHHHHHHHHHHHHCTH-HHHHHHHHHHH CS
   Rep_fac_C   1 phpteieeileaclngdfeeaykklrellvekGysaediltqlhrvvkeqeelpeaqkleilellgeiekrlveGasehlqlsallar 88 
                 php +++ +++ac +g++++a ++l+ +l++ Gys  di+++++rv k+ ++l+e++kle+++++g++++r+++G+ ++lqls+ +a+
  EEA18888.1 250 PHPIKVQAMIKACWEGKVDAALDILN-ELWNLGYSSHDIISTMFRVTKTIQTLSEHAKLEFIKEIGFTHMRILDGVGTLLQLSGCVAK 336
                 8************99**********6.***********************99********************************9986 PP

>> DNA_pol3_delta2  DNA polymerase III, delta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.5   0.0   0.00098      0.76       2      47 ..      45      89 ..      44     101 .. 0.88
   2 !   35.3   0.0   1.2e-11     9e-09      84     162 ..     104     185 ..      88     186 .. 0.89

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00098
  DNA_pol3_delta2  2 qeealkilskalksgrlahayLfeGdegigkkelalnlakallcee 47
                     ++e+++ l+ ++k g++ h  +++G  gigk ++ l+la+++l + 
       EEA18888.1 45 NTETIERLKIIAKDGNMPHV-IISGMPGIGKTTSILCLARQMLGDA 89
                     7899***************6.68*****************998765 PP

  == domain 2  score: 35.3 bits;  conditional E-value: 1.2e-11
  DNA_pol3_delta2  84 kldqirelieelsrkpre...skkkiiiiedaekmtksAaNalLktlEEPsenaifiLitsdtnklLktirSRcqelkfspl 162
                       +d +r+ i+ + +k +    +++k++i+++a+ mt+ A+ al +t+E  s+ + f +  +++nk++++++SRc +l+ s+l
       EEA18888.1 104 GIDVVRNRIKGFAQKKVTlppGRHKLVILDEADSMTPGAQQALRRTMEIYSTTTRFAFACNQSNKIIEPLQSRCAILRYSRL 185
                      7899998888888887766889******************************************************998876 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.1   0.0   1.4e-13   1.1e-10       1     128 [.      64     181 ..      64     185 .. 0.90

  Alignments for each domain:
  == domain 1  score: 42.1 bits;  conditional E-value: 1.4e-13
                 EEEESSTTSSHHHHHHHHHHHH.....THEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTS...TSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHH CS
         AAA   1 vllyGppGtGKTllakavakel.....gvefleisgsellskyvgesekkirelfkeakeka...kpsilfiDEidalaksrsgseseeeervvnqLlt 91 
                 v+++G pG+GKT+ +  +a+++     +  +le+++s+ +   +    ++i+++ ++  +     +++ +++DE+d++++             +++L +
  EEA18888.1  64 VIISGMPGIGKTTSILCLARQMlgdayKEAVLELNASDER--GIDVVRNRIKGFAQKKVT-LppgRHKLVILDEADSMTPGA-----------QQALRR 148
                 6899*****************877666789**********..999999999999998544.359888***************...........****** PP

                 HHHHTTTSSSTEEEEEEESSGGGSTHHHHSTTSSEEE CS
         AAA  92 eldgvkkkeskvivigatnrpdkldpallrgRfdrki 128
                  ++ +++   ++ +  a+n+ +k+ ++l  +R+ +  
  EEA18888.1 149 TMEIYST---TTRFAFACNQSNKIIEPLQ-SRCAILR 181
                 *******...589****************.9*98765 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.4   0.0   1.8e-09   1.4e-06       4     102 ..      63     168 ..      60     181 .. 0.77

  Alignments for each domain:
  == domain 1  score: 28.4 bits;  conditional E-value: 1.8e-09
      AAA_14   4 ilvitGaRrvGKTtllkqlikell..vkkesilyinldderdkkladpekllelilek..lke.ekktylflDEiqev.pewekalkslvd...egknl 93 
                  ++i+G+  +GKTt +  l+++ l  + ke +l++n  der  +   + ++  + ++k  l +  ++++++lDE+  + p++++al++ ++   +++++
  EEA18888.1  63 HVIISGMPGIGKTTSILCLARQMLgdAYKEAVLELNASDERGIDVVRN-RIKGFAQKKvtL-PpGRHKLVILDEADSMtPGAQQALRRTMEiysTTTRF 159
                 689*******************9999999**********999775544.355555555433.25899********754399*******99944323555 PP

      AAA_14  94 dvivtGSns 102
                  + +  Sn+
  EEA18888.1 160 AFACNQSNK 168
                 666655555 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.0     7e-07   0.00055       7      51 ..      47      88 ..      42     112 .. 0.78
   2 ?    2.6   0.0       0.2   1.6e+02     131     161 ..     123     152 ..      96     161 .. 0.70

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 7e-07
      AAA_16  7 eeleqLlsalervrsgrpelvllsGesGvGKsslvrellralekd 51
                e +e+L+ + +   +g  + v++sG++G+GK++ + +l+r++ +d
  EEA18888.1 47 ETIERLKIIAK---DGNMPHVIISGMPGIGKTTSILCLARQMLGD 88
                55555655554...666689********************99888 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.2
      AAA_16 131 srderplvlvlDdlqwadeaslqllaaLlrl 161
                 +++++  +++lD+++   ++ +q+l+ +++ 
  EEA18888.1 123 PPGRH-KLVILDEADSMTPGAQQALRRTMEI 152
                 33334.6899***************998875 PP

>> Viral_helicase1  Viral (Superfamily 1) RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.4   0.0   5.2e-08   4.1e-05       2      81 ..      65     145 ..      64     152 .. 0.82

  Alignments for each domain:
  == domain 1  score: 23.4 bits;  conditional E-value: 5.2e-08
  Viral_helicase1   2 vvhGvpGcGKStlirkllrtsliltvnrptaelltegk...pklpnlsvrtvdsflmalvkstkgkililDEylllhaGyill 81 
                      +++G+pG GK+t+i  l+r+ +   ++++++  l+++     ++ +++++++ +   +l ++ + k++ilDE+ ++++G  ++
       EEA18888.1  65 IISGMPGIGKTTSILCLARQ-MLGDAYKEAVLELNASDergIDVVRNRIKGFAQKKVTLPPG-RHKLVILDEADSMTPGAQQA 145
                      89******************.77777888777777777777888888888888877777765.8*********9999887655 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.1   0.0   1.3e-07   9.8e-05       2      58 ..      35      86 ..      34     101 .. 0.89

  Alignments for each domain:
  == domain 1  score: 22.1 bits;  conditional E-value: 1.3e-07
      RuvB_N  2 rPksleeyigqekvkeklkifieaakkreealdhvllyGpPGlGkttlakiiakelg 58
                rP  l++ +g ++  e+lki+ +     + ++ hv+++G PG+Gktt    +a+++ 
  EEA18888.1 35 RPVYLDDIVGNTETIERLKIIAK-----DGNMPHVIISGMPGIGKTTSILCLARQML 86
                9******************9854.....56789**************9999999885 PP

>> AAA_3  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5   0.0   1.1e-07   8.3e-05       1      92 [.      63     156 ..      63     170 .. 0.82

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 1.1e-07
       AAA_3   1 hvllegvPGlaktllvkalakaldlefkriqftpdllPsdilGtevfeekekefefkk...Gpvfanllladeinrappktqsalleameerqvt 92 
                 hv++ g+PG++kt+ +  la+++  +  +     +l  sd  G++v++++ k f  kk    p  ++l++ de +  +p +q al  +me    t
  EEA18888.1  63 HVIISGMPGIGKTTSILCLARQMLGDAYK-EAVLELNASDERGIDVVRNRIKGFAQKKvtlPPGRHKLVILDEADSMTPGAQQALRRTMEIYSTT 156
                 9*******************988766555.445689999999999999998777655511156689**********************9876655 PP

>> DNA_pol3_delta  DNA polymerase III, delta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0   0.0   2.9e-07   0.00022      58     170 ..     127     229 ..     105     230 .. 0.92

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 2.9e-07
                     EEEEEEE--.....TT-S-TTHHHHHHHHTTT--SSEEEEEEES.S--HHHHHHHHHTTTEEEEEE----TTTHHHHHHHHHHHTT-EE-HHHHH CS
  DNA_pol3_delta  58 krivvlknpklltkesklnekllkeLeeylsnlpedtlLiliapkklderkklvklLkkkatvveaktlkeeelkkwiqkraqelglkiekeale 152
                      ++v+l+ +      ++ +   +++L ++++ ++++t + + ++    + +k++  L+++  ++++++l+  ++ k +++++++++++++++ + 
      EEA18888.1 127 HKLVILDEA------DSMTPGAQQALRRTMEIYSTTTRFAFACN----QSNKIIEPLQSRCAILRYSRLTDGQVVKRLSQICEAEKVDFSEDGIA 211
                     577777777......4578888999*******************....6789******************************************* PP

                     HHHHHHTT-HHHHHHHHH CS
  DNA_pol3_delta 153 lLlelvennlsaikqele 170
                      L+ + e++++++ ++l+
      EEA18888.1 212 ALVFSAEGDMRQAINNLQ 229
                     ****************97 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.7   0.1   0.00061      0.47       7      30 ..      63      86 ..      57     113 .. 0.81
   2 !    8.2   0.0    0.0037       2.9      82     118 ..     112     152 ..      88     166 .. 0.69

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00061
      AAA_22  7 ilvvtGesGtGKTtllrrlleqld 30
                ++++ G +G+GKTt++  l++q  
  EEA18888.1 63 HVIISGMPGIGKTTSILCLARQML 86
                789*************99999865 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.0037
      AAA_22  82 leqalrarav.....ielliiDEaqhlrseealeeLrsllnl 118
                 +   ++++ +     ++l+i+DEa+ + ++ a + Lr+ +++
  EEA18888.1 112 IKGFAQKKVTlppgrHKLVILDEADSM-TPGAQQALRRTMEI 152
                 55555555556667789**********.87777777777665 PP

>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   8.8e-06    0.0068       8      77 ..      29      94 ..      24     119 .. 0.85

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 8.8e-06
       Rad17  8 lWfekykPekaeelavhkkkieevkewlkadvLesrkkriLLisGPsGCgkstvvkvLske.lgiklrewl 77
                +W+eky+P  ++++    + ie +k   k   +++      +isG +G gk+t +  L+++ lg  ++e +
  EEA18888.1 29 PWVEKYRPVYLDDIVGNTETIERLKIIAKDGNMPHV-----IISGMPGIGKTTSILCLARQmLGDAYKEAV 94
                8***********************999998888877.....9****************9862677777755 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.8   0.0   7.2e-05     0.056       2      58 ..      39      98 ..      38     103 .. 0.80
   2 ?    0.5   0.0      0.41   3.2e+02     109     132 ..     129     152 ..     116     162 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 7.2e-05
  Mg_chelatase  2 lkdvkGqeeakraleiaaa.Gg.HnlllvGppGsGKtmlakrlp.sllpplseeealeva 58
                  l d++G++e+ + l+i a  G+  ++++ G pG GKt  + +l+ ++l +  +e +le +
    EEA18888.1 39 LDDIVGNTETIERLKIIAKdGNmPHVIISGMPGIGKTTSILCLArQMLGDAYKEAVLELN 98
                  6899***999999998665254359************99988852688888888888876 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.41
  Mg_chelatase 109 vLfLDElpefkrkvlevLRePled 132
                   +++LDE+  ++  + ++LR+ +e 
    EEA18888.1 129 LVILDEADSMTPGAQQALRRTMEI 152
                   679*****************9996 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.7   0.0    0.0004      0.32       5      87 ..      64     148 ..      60     162 .. 0.63
   2 ?    2.9   0.0     0.099        77     102     144 ..     260     306 ..     246     324 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.0004
      AAA_24   5 iliyGpsgiGKTtlakel.......gpkplfidtekGlks.ldadkfpdieswedfldevvelaaeladyktlviDtideleelclaevir 87 
                 ++i G +giGKTt+++ l        +k +++ ++++  + +d+ +      ++ f ++ v+l+   +  k +++D +d +   + + ++r
  EEA18888.1  64 VIISGMPGIGKTTSILCLarqmlgdAYKEAVLELNASDERgIDVVRN----RIKGFAQKKVTLPPGRH--KLVILDEADSMTPGAQQALRR 148
                 7899***********99977777775666666665544321333332....34555555555554444..666777777666666666655 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.099
      AAA_24 102 kG.ygelaeefrrllkklqelrk...nvifiahektrkdedpegeak 144
                 k+ +    +   ++l+ l++l++   ++i ++   t+++++  + ak
  EEA18888.1 260 KAcWEGKVDAALDILNELWNLGYsshDIISTMFRVTKTIQTLSEHAK 306
                 677888899999********************999999988766644 PP

>> MeaB  Methylmalonyl Co-A mutase-associated GTPase MeaB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   2.4e-05     0.019      21      69 ..      53     101 ..      30     119 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 2.4e-05
                 HHGGG-S-SEEEEEEE-TTSSHHHHHHHHHHHHHCTT--EEEEEE---- CS
        MeaB  21 rllakaGraqvvGltGvPGaGkstlvealglelrrrGkrvavlavDPss 69 
                 +++ak G+   v + G+PG Gk t +  l+ ++    ++ avl ++ s 
  EEA18888.1  53 KIIAKDGNMPHVIISGMPGIGKTTSILCLARQMLGDAYKEAVLELNASD 101
                 578999************************************9887664 PP

>> AAA_assoc_2  AAA C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   5.5e-05     0.043       3      32 ..     201     230 ..     199     261 .. 0.91

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 5.5e-05
                  X.XXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  AAA_assoc_2   3 kklkleddalealaeladGDaRkaLnlLEl 32 
                  +k+++++d ++al+  a+GD+R+a+n L+ 
   EEA18888.1 201 EKVDFSEDGIAALVFSAEGDMRQAINNLQS 230
                  68999**********************985 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   3.2e-05     0.025      17      43 ..      62     119 ..      46     198 .. 0.64

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 3.2e-05
      AAA_11  17 seitliqGPPGtgKTktivellsqll................................s 43 
                 ++ ++i+G PG gKT+ i+ l +q+l                                +
  EEA18888.1  62 PH-VIISGMPGIGKTTSILCLARQMLgdaykeavlelnasdergidvvrnrikgfaqkK 119
                 44.89********************7666655555555555444444444444444440 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   7.9e-05     0.062       7      75 ..      58     129 ..      52     227 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 7.9e-05
      AAA_19   7 alkekvllvtaGpGtGKTrvlkhivallvelggvkpeeillvaftgrAakelrerlaalgaeatTi....Hrl 75 
                 + + +++++ + pG GKT+ + +  + ++       + + l a  +r  + +r+r++++ ++  T+    H+l
  EEA18888.1  58 DGNMPHVIISGMPGIGKTTSILCLARQMLGDAYK-EAVLELNASDERGIDVVRNRIKGFAQKKVTLppgrHKL 129
                 55678899***************99988877644.35556678888888888888888888866653333555 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   0.00019      0.14       1      22 [.      63      84 ..      63      93 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00019
                EEEEE--TTSSHHHHHHHHHHH CS
    NTPase_1  1 kvfiTGppGvGKtTlvkkvlel 22
                +v+i+G+pG+GKtT +  ++++
  EEA18888.1 63 HVIISGMPGIGKTTSILCLARQ 84
                79************99877665 PP

>> TniB  Bacterial TniB protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.0    0.0028       2.2      20      52 ..      46      78 ..      30      96 .. 0.84
   2 ?    2.7   0.0     0.092        72     119     144 ..     126     151 ..     107     154 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0028
        TniB 20 lerLeeLleypkrkrmpnlllvGdsnnGKtmiv 52
                +e++e+L   +k   mp++++ G + +GKt+ +
  EEA18888.1 46 TETIERLKIIAKDGNMPHVIISGMPGIGKTTSI 78
                5678888889999*****************865 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.092
        TniB 119 kvrvLiiDEihnllagsarkqrefln 144
                 + +++i+DE +++  g +++ r++++
  EEA18888.1 126 RHKLVILDEADSMTPGAQQALRRTME 151
                 5799************9999988875 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   0.00047      0.36      36      92 ..      64     114 ..      45     153 .. 0.69
   2 ?   -0.9   0.0       1.4   1.1e+03     144     162 ..     128     146 ..     123     165 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00047
      AAA_25  36 allaGapgtGKttlaldlalavatGkpwlgpvapeqgkVlyvsaEds..edelrrRlra 92 
                 +++ G pg GKtt  l la  ++ +          + +Vl ++a d    d +r+R++ 
  EEA18888.1  64 VIISGMPGIGKTTSILCLARQMLGDA--------YKEAVLELNASDErgIDVVRNRIKG 114
                 6899*****************99433........2335665555444114566666665 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 1.4
      AAA_25 144 rlvviDplsralggdensn 162
                 +lv++D  +++++g  ++ 
  EEA18888.1 128 KLVILDEADSMTPGAQQAL 146
                 79*****999999976655 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00038       0.3      21     101 ..      64     139 ..      51     162 .. 0.66

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00038
      AAA_30  21 avltGpAGtGKttalkal.reaweaa.ggrvi.glAptgkaAkvLaeelgieastiakllkrlkgrarlepgtllivDEagmvd 101
                 +++ G +G GKtt++  l r+++ +a ++ v+ + A+ ++  +v+++ +   a+  +k++  l       +++l+i DEa  + 
  EEA18888.1  64 VIISGMPGIGKTTSILCLaRQMLGDAyKEAVLeLNASDERGIDVVRNRIKGFAQ--KKVT--LPP----GRHKLVILDEADSMT 139
                 799**********98887588888776666663557777777777766443333..2333..122....356899999986653 PP

>> KTI12  Chromatin associated protein KTI12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00023      0.18       1      78 [.      61     134 ..      61     180 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00023
                 E.EEEEE--TTSSHHHHHHHHHHHHHHTT--EEEE-THHHH.TTSSS--GGGHHHHHHHHHHHHHHHHT....T.SEEEE-S CS
       KTI12   1 MpLvvltGlPssGKstrakeLakaleeekrsvvviddeslgiekdsykdsakekalRsslrsavkrdLs....kekvVIvDs 78 
                 Mp v+++G+P  GK+t    La+++    ++  v++ ++          ++    +R++++  ++++++    ++k+VI+D+
  EEA18888.1  61 MPHVIISGMPGIGKTTSILCLARQMLGDAYKEAVLELNASD--------ERGIDVVRNRIKGFAQKKVTlppgRHKLVILDE 134
                 9*********************9999998888887765544........233333333333333333322222677777776 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.1      0.13     1e+02      16      39 ..      63      86 ..      47      97 .. 0.78
   2 ?    6.9   0.0    0.0064         5     117     147 ..     122     151 ..      87     163 .. 0.71

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.13
                EEEEEESTTSSHHHHHHHHHHHHH CS
                xxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD 16 dvlvaaeTGsGKTlaflipvlqiv 39
                +v++++  G GKT+  l  + q +
  EEA18888.1 63 HVIISGMPGIGKTTSILCLARQML 86
                7999**********9988877766 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0064
                 SHCTTEEEEEEETHHHHHHTTTHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD 117 lnlsqvrflVlDEadrlldqgfsdfinriln 147
                 l   + ++++lDEad +     ++ ++r ++
  EEA18888.1 122 LPPGRHKLVILDEADSMTPG-AQQALRRTME 151
                 44567799********9985.6666766554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (350 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       506  (0.0282224); expected 358.6 (0.02)
Passed bias filter:                      501  (0.0279436); expected 358.6 (0.02)
Passed Vit filter:                        89  (0.00496402); expected 17.9 (0.001)
Passed Fwd filter:                        23  (0.00128284); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              23  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 2439.22
//
Query:       EEA18889.1  [L=305]
Description: sucrase/ferredoxin-like family protein Fmi1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.1e-58  197.4   0.0    2.4e-58  197.2   0.0    1.0  1  Suc_Fer-like  Sucrase/ferredoxin-like


Domain annotation for each model (and alignments):
>> Suc_Fer-like  Sucrase/ferredoxin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  197.2   0.0   1.3e-62   2.4e-58       1     195 []      13     294 ..      13     294 .. 0.90

  Alignments for each domain:
  == domain 1  score: 197.2 bits;  conditional E-value: 1.3e-62
  Suc_Fer-like   1 llgtvkayskhvlvatgksdWpskvede.kg....slaealkkl.k...........lllsasslp.eekseeekttvlllPdfklveevt...... 73 
                   l+ t+++y+++vl+atg++dW s++e++  +    sl++ lk++ +           l +++ss++ +++ ++  ++++l+P+fk+v++++      
    EEA18889.1  13 LNATMAPYTQQVLIATGQTDWSSRIEEDgVEkswgSLVRGLKDMfGrggkyadpynnLAVTNSSFKpTAQASSPFASAFLFPAFKYVPKIPiatntd 109
                   6789********************55542335788999999998669*******************75566777899***********999999998 PP

  Suc_Fer-like  74 ...pssveelvkeflkp..............................kvrklpekaliLvCshktrDarCgilapllrkelerelre.....ke... 129
                      +s+++++++++l p                              ++ +++++ +iL+Csh+ rD+rCg+++p+l++e+er+lr+     ++   
    EEA18889.1 110 aktESNLDSFARAYLLPyklhsahsgipesqrqimtrspeyasqyfpEALDIKQSPTILICSHGGRDMRCGVMGPVLHAEFERVLRRkgfttNDdss 206
                   8888888899999999899***************************9888899999*******************************6666511444 PP

  Suc_Fer-like 130 ....derpggvrvgfisHvGGHkfAgnviiyrkek..................agqgiwygrvepedvegiveetilkgkvvkellRg 195
                        + p++++++ isHvGGHk+Agnviiy+++                   ag+giwygrvep++veg+veeti +g+vv++++Rg
    EEA18889.1 207 agnrIDGPTHANIASISHVGGHKYAGNVIIYIPPAlmttssslgtivsspsplAGKGIWYGRVEPKHVEGLVEETIFNGRVVEDHFRG 294
                   444455666******************************************************************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (305 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       262  (0.0146132); expected 358.6 (0.02)
Passed bias filter:                      245  (0.013665); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.28s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 2095.57
//
Query:       EEA18890.1  [L=335]
Description: CaaX prenyl proteinase Rce1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.2e-17   61.8   6.0    6.2e-17   61.8   6.0    2.9  3  CPBP      CPBP intramembrane metalloprotease


Domain annotation for each model (and alignments):
>> CPBP  CPBP intramembrane metalloprotease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.9      0.11   1.9e+03      77      77 ..      92      92 ..      24     130 .. 0.56
   2 !   61.8   6.0   3.5e-21   6.2e-17       6      91 ..     154     260 ..     149     261 .. 0.85
   3 ?   -1.3   0.6      0.17     3e+03      51      80 ..     306     331 ..     289     335 .] 0.62

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.11
                T CS
        CPBP 77 g 77
                +
  EEA18890.1 92 N 92
                0 PP

  == domain 2  score: 61.8 bits;  conditional E-value: 3.5e-21
                 HHHHHHHHHHHHHHHHHHTTCHHHH.HHHH.S-HHHHHHHHHHHHHCSGGG....................HHHHHHHHHHHHHHHHHHHHTT-HHHHH CS
        CPBP   6 lvfllalllapllEEllfRglllql.lqergsstlailissilFglaHlpn....................gpsvllaalaGlvlgylylktgsllaai 83 
                 ++ +++++ +p++EE++fR+++++l l ++ s+  ++++s + Fg+aH+++                     +++++++++G++ ++lyl+tgsl a+i
  EEA18890.1 154 WIGFRNYVAGPITEEIIFRSVIITLhLLAKMSPGRIVFVSPLYFGIAHIHHfyefrlthpdtpipailfrsIFQFAYTTVFGWFAAFLYLRTGSLPAVI 252
                 7899*****************99863334457789****************777777777777777766644446************************ PP

                 HHHHHHHH CS
        CPBP  84 llHallnl 91 
                 l+H+++n+
  EEA18890.1 253 LVHSFCNW 260
                 *******7 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.17
                 CSGGGHHHHHHHHHHHHHHHHHHHHTT-HH CS
        CPBP  51 aHlpngpsvllaalaGlvlgylylktgsll 80 
                 a+++    +l+a ++G+++++  l + +l+
  EEA18890.1 306 AYYV----LLVAGAVGFYYALWPLTESKLA 331
                 3332....4777777777776555554455 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (335 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       605  (0.0337442); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.46
# Mc/sec: 2169.48
//
Query:       EEA18891.1  [L=749]
Description: serine-rich protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (749 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       555  (0.0309554); expected 358.6 (0.02)
Passed bias filter:                      349  (0.0194657); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.66u 0.30s 00:00:00.96 Elapsed: 00:00:00.49
# Mc/sec: 4615.56
//
Query:       EEA18892.1  [L=1782]
Description: cytokinesis protein SepA/Bni1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.6e-87  292.3   7.1    5.6e-87  292.3   7.1    2.6  4  FH2            Formin Homology 2 Domain
    1.3e-66  223.8   1.1    2.7e-66  222.7   0.0    2.2  2  Drf_GBD        Diaphanous GTPase-binding Domain
    1.7e-51  174.6   3.9      3e-50  170.6   0.0    3.0  3  Drf_FH3        Diaphanous FH3 Domain
  ------ inclusion threshold ------
        1.2    9.2   9.3      0.071   13.2   1.3    2.8  2  TssO           Type VI secretion system, TssO


Domain annotation for each model (and alignments):
>> FH2  Formin Homology 2 Domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   1.4      0.36   1.6e+03     279     335 ..     766     827 ..     751     851 .. 0.55
   2 ?   -3.9   3.5       1.3   5.6e+03     256     312 ..     797     853 ..     779     895 .. 0.61
   3 ?   -1.5   0.4      0.23     1e+03     286     330 ..     872     922 ..     868     938 .. 0.72
   4 !  292.3   7.1   1.2e-90   5.6e-87       3     372 .]    1118    1514 ..    1116    1514 .. 0.97

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.36
                 HHHHHHHHHHHHH.HHHHHHHHHHCCT....TSSTT-THHHHHHHHHHHHHHHHHHHHHHHH CS
         FH2 279 eslekevkklekg.lkklekelessek....keepsdkflevlkeflkeaeeklkkleeelk 335
                 ++++++++   +g +kkl+k++e++++    ++ ++d +++ l+++ +  +++l++ e e +
  EEA18892.1 766 DEMKAQIELGADGlVKKLQKQIEEQASvlelQRRQNDSLKSELNDVHRLRAQELQRNELETR 827
                 55555555544442467777777777733334445555555555554444444444443333 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 1.3
                 TSGGGGGHHHHTTTHHHCCTS-HHHHHHHHHHHHHHHHHHHHHHHHCCTTSSTT-TH CS
         FH2 256 klpevldfsseLknvkkaakvnleslekevkklekglkklekelessekkeepsdkf 312
                 +  + + ++seL++v ++ + +l+  e e+++l+  l+++++ + s++kk+ p++k+
  EEA18892.1 797 QRRQNDSLKSELNDVHRLRAQELQRNELETRELYLMLRDAQDIAASNAKKQAPENKL 853
                 445555667777777777777777777777777777777777666666655555554 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 0.23
                 HHHHHHHHHHHHHHHHCCT......TSSTT-THHHHHHHHHHHHHHHHHHH CS
         FH2 286 kklekglkklekelessek......keepsdkflevlkeflkeaeeklkkl 330
                 + le++l+ ++++++ + k      +++   +++e+++  l++ ee+++k 
  EEA18892.1 872 ERLERQLERTKTQFKLEGKvwnqdgPSDRLRELREQMEGALAQPEEEFEKK 922
                 578899999999999999988855555555666778888888888888764 PP

  == domain 4  score: 292.3 bits;  conditional E-value: 1.2e-90
                  XX---SS-B------EESSGGCTTSCCCCTCCHHHHC.........TSHHHHHHHHTBSC--HCCH......HCSCCTTCCESSS-HHHHHHHHHHH CS
         FH2    3 kkikpkkkLkplhWdkvkpsqdrstvWdklkeesfek.........eldlseleelFsakekkkkkkksekskkskkkkkkvklLdpkrsqniaIlL 90  
                   +i+pkkkLk lhWdk+++ q++  vW+++  + ++k         +++l+e+e+lF+ake+k    +      ++k+k+k +++++++s+++++ L
  EEA18892.1 1118 PSIRPKKKLKALHWDKIDTPQVT--VWASHAPTTEAKeekytdlakKGVLDEVERLFMAKETKILGGG----NTAQKRKDKKQIISNELSKTFQVAL 1208
                  5789******************8..****99998888899***********************99999....99999999***************** PP

                  HHH.TS-HHHHHHHHHTTTTCCCT.............HHHHHHHH.HHCGGHHHHHHH....HCTCTSGTTB-HHH.HHHHHHTT.STTHHHHHHHH CS
         FH2   91 kkl.kltaeeiveaileldeeald.............lellenLl.kmaPtkeelkkl....keykgevseLseae.qFllelvk.iprlekRleal 166 
                   k+ + +++e+v++i+++d+e+++             +++ en +  maP++++++      +e +++++eL++++ ++l++  + ++++++R++al
  EEA18892.1 1209 AKFsQTSVDELVRMIIHCDKEIMEndvvmdflqrddlCNIAENTAkLMAPYSKDWTVAdaatAEREQDINELTREDqIYLQTAYElNHYWKSRMRAL 1305
                  *************************************99****9989*********996544455555********9******************** PP

                  HHHHTHHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHSTCSTTCS-SEE-GGGGGGCCCSB-STTTSBHHHHHHHHHHTTSGGGGGH CS
         FH2  167 lfkstfeeeveelkrslealeaaseeLknskkfkklLeliLalGNymNdgtrrgqAkGFkLssLlkLsdvKstdnkttLLHylvkiireklpevldf 263 
                  ++  ++e+++ +++++++++ +++++L++s +++++L liL +GN+mNd++  +qA+GFkL sL +L +vK+++n+tt+ +++++i+r+++pe+++f
  EEA18892.1 1306 ALTRSYEADYDHISTKIQEVAQVCDSLRDSVSLMNVLGLILDIGNFMNDAN--KQAQGFKLGSLARLGMVKDDKNETTFADLVERIVRNQYPEWEGF 1400
                  *************************************************88..9******************************************* PP

                  HHHTTTHHHCCTS-HHHHHHHHHHHHHHHHHHHHHHHHCCT....TSSTT-THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT--TT.CC CS
         FH2  264 sseLknvkkaakvnleslekevkklekglkklekelessek....keepsdkflevlkeflkeaeeklkkleeelkeakelvkelveYfgedkk.ev 355 
                  ++e+  v  + k+n+++l+++  k+   +k+++ +l+s++     k++p+d++++v+++ +kea++k ++++ +l+++ +++++++ ++ged++ e 
  EEA18892.1 1401 QDEIGGVAGVHKLNIDNLRQDAVKYINTIKNVQSSLDSGNLsdpkKFHPQDRVSQVVQRNMKEARRKAEQMQILLDDLAKTFDDIMTFYGEDNTdEN 1497
                  *******************************************************************************************9999** PP

                  HHHHHHHHHHHHHHHHH CS
         FH2  356 speeffkilreFlkefk 372 
                  s++ ff +l++Fl+e+k
  EEA18892.1 1498 SRRDFFGKLASFLQEWK 1514
                  **************996 PP

>> Drf_GBD  Diaphanous GTPase-binding Domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  222.7   0.0   5.9e-70   2.7e-66       4     188 .]     293     502 ..     290     502 .. 0.97
   2 ?   -3.7   0.7       1.7   7.4e+03      56      80 ..     779     803 ..     732     826 .. 0.39

  Alignments for each domain:
  == domain 1  score: 222.7 bits;  conditional E-value: 5.9e-70
     Drf_GBD   4 pdeeeidklFeelleel...nlpeekreallalpiekKwqlvvqdkkkkakke..............eklsksksksneeespesyvkklkddslkekq 85 
                 +d++ +d+lF el++++   nlpe++++++la+p++kKw+lv+qd+ ++ ++e               +      +++ee+spe+yvkk++dd++++kq
  EEA18892.1 293 KDDRMVDQLFLELMQKRgwqNLPEQAKRQMLAYPASKKWTLVHQDRLTELQGEqkrrnnarlthgydSGSLTVIGRADEEGSPEWYVKKVMDDTITSKQ 391
                 5999***********************************************************9887666777789*********************** PP

     Drf_GBD  86 lesLrVaLrtqplsWvkrFieleGlvaLlnvLskinekkaee........eedlkkeyeiikClKalmNnkvGldavlahksvikllaqsldserlktr 176
                 l sL+V+Lrtqp+sWvk F+e++G+vaL+nvL kin++k  +        ++dl++ey+i kClKalmNnk+G+d++lah++vi +l++sl+s+rl+tr
  EEA18892.1 392 LGSLSVSLRTQPISWVKAFVEAQGQVALTNVLLKINRRKTAGpgpvvsgaDKDLEREYDITKCLKALMNNKYGADDALAHQQVIVALVSSLLSPRLQTR 490
                 *************************************************************************************************** PP

     Drf_GBD 177 klvlelLtalcl 188
                   v+++Lt+lc+
  EEA18892.1 491 RIVSDVLTFLCH 502
                 ***********8 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 1.7
     Drf_GBD  56 lsksksksneeespesyvkklkdds 80 
                 l k+ +k+ ee+ +    + +++ds
  EEA18892.1 779 LVKKLQKQIEEQASVLELQRRQNDS 803
                 2223333333333322233333333 PP

>> Drf_FH3  Diaphanous FH3 Domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.0   0.0    0.0037        17       1      23 [.     507     529 ..     507     531 .. 0.94
   2 !  170.6   0.0   6.7e-54     3e-50       2     195 .]     531     734 ..     530     734 .. 0.96
   3 ?   -3.5   0.5       1.4   6.4e+03      91     126 ..     782     817 ..     773     849 .. 0.57

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0037
                 THHHHHHHHHHHHHHCCT-SSTT CS
     Drf_FH3   1 eghekvleatldfkevaeergrf 23 
                 +gh+kvl+a+++ k+ + e grf
  EEA18892.1 507 QGHQKVLQAMDHVKNHNGETGRF 529
                 69********************9 PP

  == domain 2  score: 170.6 bits;  conditional E-value: 6.7e-54
                 HHHHHHHHHHHHHHCCT-SSTTHHHHHHHHH........HSS-HHHHHHHHHHHHHHHHSSS.SHHHHHHHHHHHHCTTHHHHHHHHCTSCSHHHHHHH CS
     Drf_FH3   2 ghekvleatldfkevaeergrfrslvgaldel.......enelveykvatmllInalvnspe.dlqfRlhLRseflalGLdkiidklreleneeLddql 92 
                 ++++++e t+d+      rg+++slvga++e+       en+l+ey+vatm +In+lv++p+ dlq+R+h+R++f+a+G++++++k++ +++e +d+q+
  EEA18892.1 531 AWMRIVEVTIDG------RGKMGSLVGASEEFrsggvgmENQLMEYAVATMMMINMLVDAPQyDLQLRCHIRAQFIACGIKRLLTKMEGFQYEIIDKQI 623
                 8***********......*******************************************66************************************ PP

                 HHHHHHHHHHHHHHHHHHT........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
     Drf_FH3  93 qafeeerneDeeellerae........dktvdlddpeelfellknkvkdteaepyllsilqhllli..rddeeekesylklleelvsqivlqrtkidpk 181
                 ++f+e+++ D+e+ll+r+          +  d++dp ++ + ++ k+++t+a +y+ls++qh+lli  + + +++ ++++l+e+++s+++++r+ +d  
  EEA18892.1 624 ERFRENEAIDYEDLLQREGssakdsveGEVKDMSDPAQITDAINMKLQGTRAGDYFLSAMQHMLLIreNSSGDDGLRMFQLVEAMLSYVAMDRRLPDL- 721
                 ***************888778888888999************************************98888999********************9666. PP

                 XXXXXXXXXXXXXX CS
     Drf_FH3 182 kderkslevaieeL 195
                  d r+ l +++++L
  EEA18892.1 722 -DLRQGLTFTVQNL 734
                 .9999999999987 PP

  == domain 3  score: -3.5 bits;  conditional E-value: 1.4
                 HHHHHHHHHHHHHHHHHHHHT.XXXXXXXXXXXXXXX CS
     Drf_FH3  91 qlqafeeerneDeeellerae.dktvdlddpeelfel 126
                 +lq+  ee++  + el++r++ + + +l+d+ +l  +
  EEA18892.1 782 KLQKQIEEQA-SVLELQRRQNdSLKSELNDVHRLRAQ 817
                 4444444444.56666666665667777777666433 PP

>> TssO  Type VI secretion system, TssO
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   1.4      0.56   2.5e+03      42      98 ..     782     840 ..     780     885 .. 0.82
   2 ?   13.2   1.3   1.6e-05     0.071      68     143 ..    1458    1536 ..    1448    1540 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.56
        TssO  42 illkelerkkkfeekqkelkkkvdsiykkIdsL..kpevnavfleneIkkdlndiknty 98 
                 +l k++e++++++e q  +++ ++s  +++ +L  +  + +  +++e+   l+d++++ 
  EEA18892.1 782 KLQKQIEEQASVLELQRRQNDSLKSELNDVHRLraQELQRNELETRELYLMLRDAQDIA 840
                 45699999999999999999999999999999976666667777778877777777766 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 1.6e-05
        TssO   68 ykkIdsL.kpevnavfleneIkkdlndikntygknssd..eRykmyaqiakfykmlledKkelksvseniklfkkqLee 143 
                  +++++    + ++ + l +++ k   di   yg++++d  +R +++  +a+f++++ ++K++ + ++en  +++++L +
  EEA18892.1 1458 QRNMKEArRKAEQMQILLDDLAKTFDDIMTFYGEDNTDenSRRDFFGKLASFLQEWKKSKEKNIALEENRRRIESSLAR 1536
                  56666666778888899999************775554227********************************999965 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1782 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1372  (0.0765241); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.20u 0.35s 00:00:01.54 Elapsed: 00:00:00.56
# Mc/sec: 9583.49
//
Query:       EEA18893.1  [L=178]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (178 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       628  (0.0350271); expected 358.6 (0.02)
Passed bias filter:                      439  (0.0244855); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1156.45
//
Query:       EEA18894.1  [L=400]
Description: DNA-binding protein eta2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.9e-32  111.2   6.2    7.6e-12   45.2   0.1    3.3  3  Myb_DNA-binding  Myb-like DNA-binding domain
    1.7e-30  105.1   1.6    1.6e-12   47.5   0.1    3.4  3  Myb_DNA-bind_6   Myb-like DNA-binding domain
    0.00043   20.1   0.2      0.023   14.6   0.1    2.9  3  Myb_DNA-bind_7   Myb DNA-binding like
  ------ inclusion threshold ------
      0.051   13.6   0.5        3.9    7.5   0.0    3.4  4  SLIDE            SLIDE
      0.052   13.8   0.6       0.42   10.8   0.1    2.2  2  SANT_DAMP1_like  SANT/Myb-like domain of DAMP1
       0.15   12.4   3.6         16    5.9   0.1    3.1  3  MADF_DNA_bdg     Alcohol dehydrogenase transcription factor M


Domain annotation for each model (and alignments):
>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.6   1.5   6.3e-13   1.9e-09       1      43 [.       5      50 ..       5      52 .. 0.90
   2 !   45.2   0.1   2.6e-15   7.6e-12       2      46 .]      60     104 ..      59     104 .. 0.97
   3 !   29.5   0.0   2.1e-10   6.2e-07       1      45 [.     110     155 ..     110     156 .. 0.92

  Alignments for each domain:
  == domain 1  score: 37.6 bits;  conditional E-value: 6.3e-13
                     CSSSBHHHHHHHHHHHHH..HT.TCHHHHHHHHTSS-HHHHHHHHH CS
  Myb_DNA-binding  1 rgkWteeEdelLleavkk..hG.nrWkkIaerlggRtekqcrsrwr 43
                     r+ W+ eEd  L ++v+    G ++W+ Ia++l+gR  k+cr rw+
       EEA18894.1  5 RNLWSVEEDTTLRRLVESceKGkVDWRVIASYLPGRNNKDCRKRWH 50
                     567**************95555777********************7 PP

  == domain 2  score: 45.2 bits;  conditional E-value: 2.6e-15
                      SSSBHHHHHHHHHHHHHHTTCHHHHHHHHTSS-HHHHHHHHHHHT CS
  Myb_DNA-binding   2 gkWteeEdelLleavkkhGnrWkkIaerlggRtekqcrsrwrnyl 46 
                      g+W++ EdelL  ++++hG  W+++a+ +g+R + qc  rw+++l
       EEA18894.1  60 GPWSQGEDELLKMGIHRHGPHWSRVAQVVGTRNGDQCFKRWNDVL 104
                      89***************************************9875 PP

  == domain 3  score: 29.5 bits;  conditional E-value: 2.1e-10
                      CSSSBHHHHHHHHHHHHHHTTCHHHHHH.HHTSS-HHHHHHHHHHH CS
  Myb_DNA-binding   1 rgkWteeEdelLleavkkhGnrWkkIae.rlggRtekqcrsrwrny 45 
                      r++Wt eEd lLl a+ ++G  Wk I + +++gRt+ + ++r r++
       EEA18894.1 110 RSPWTREEDRLLLLAIGEYGRAWKMIVDtYFPGRTGLDAKNRHRQL 155
                      789***********************665*********99998876 PP

>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.5   0.1   5.4e-16   1.6e-12       1      60 []       8      70 ..       8      70 .. 0.96
   2 !   47.4   0.1   5.6e-16   1.7e-12       1      60 []      62     121 ..      62     121 .. 0.98
   3 !   23.2   0.0   2.1e-08   6.2e-05       1      51 [.     113     163 ..     113     179 .. 0.84

  Alignments for each domain:
  == domain 1  score: 47.5 bits;  conditional E-value: 5.4e-16
  Myb_DNA-bind_6  1 WteeEdeiLlklvekygn...dWknIaealnrRtpkqcfdrwknkLrpkisrkkwskeedirL 60
                    W++eEd +L++lve +++   dW+ Ia+ l+ R+ k+c+ rw++++++ ++ ++ws+ ed++L
      EEA18894.1  8 WSVEEDTTLRRLVESCEKgkvDWRVIASYLPGRNNKDCRKRWHYRVSATMNLGPWSQGEDELL 70
                    ****************98889*********55***************************9987 PP

  == domain 2  score: 47.4 bits;  conditional E-value: 5.6e-16
  Myb_DNA-bind_6   1 WteeEdeiLlklvekygndWknIaealnrRtpkqcfdrwknkLrpkisrkkwskeedirL 60 
                     W++ Ede+L  +  ++g  W+ +a+  + R+  qcf rw+ +L+p i r++w++eed++L
      EEA18894.1  62 WSQGEDELLKMGIHRHGPHWSRVAQVVGTRNGDQCFKRWNDVLDPAIDRSPWTREEDRLL 121
                     ***************************99****************************876 PP

  == domain 3  score: 23.2 bits;  conditional E-value: 2.1e-08
  Myb_DNA-bind_6   1 WteeEdeiLlklvekygndWknIaeal.nrRtpkqcfdrwknkLrpkisrkk 51 
                     Wt eEd++Ll    +yg+ Wk I + + + Rt ++ ++r+++ L  k++r++
      EEA18894.1 113 WTREEDRLLLLAIGEYGRAWKMIVDTYfPGRTGLDAKNRHRQ-LTRKRKRES 163
                     ***********************7775466************.866666653 PP

>> Myb_DNA-bind_7  Myb DNA-binding like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0       0.1     3e+02      28      49 ..      28      49 ..       2      52 .. 0.68
   2 ?   -0.5   0.0      0.38   1.1e+03       9      44 ..      60      95 ..      50     102 .. 0.83
   3 !   14.6   0.1   7.8e-06     0.023       8      70 ..     110     180 ..     106     191 .. 0.69

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.1
  Myb_DNA-bind_7 28 tDFsliaklfpkrtrrqlKlKF 49
                     D+ +ia+++p+r+ ++ ++++
      EEA18894.1 28 VDWRVIASYLPGRNNKDCRKRW 49
                    5999**********99988776 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.38
  Myb_DNA-bind_7  9 kkWskeetekFYkaLsqfGtDFsliaklfpkrtrrq 44
                     +Ws+ e e+   +++  G  +s +a++   r+ +q
      EEA18894.1 60 GPWSQGEDELLKMGIHRHGPHWSRVAQVVGTRNGDQ 95
                    58******999999*****99999999999888776 PP

  == domain 3  score: 14.6 bits;  conditional E-value: 7.8e-06
  Myb_DNA-bind_7   8 tkkWskeetekFYkaLsqfGtDFsli.aklfpkrt.......rrqlKlKFkkEerknpeliekalkkrkel 70 
                     +++W+ ee ++   a+ ++G  +++i  ++fp+rt       +rql +K k+E +   +  + ++kk+++ 
      EEA18894.1 110 RSPWTREEDRLLLLAIGEYGRAWKMIvDTYFPGRTgldaknrHRQLTRKRKRESKPSTKTTKTTIKKEQQP 180
                     679*********************983679***77222222245666666666666666666666665553 PP

>> SLIDE  SLIDE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0      0.21   6.4e+02      46      76 ..       2      34 ..       1      52 [. 0.82
   2 ?    0.4   0.0      0.21   6.2e+02      49      77 ..      59      86 ..      41      92 .. 0.78
   3 ?    7.5   0.0    0.0013       3.9      49      76 ..     110     136 ..     102     141 .. 0.82
   4 ?   -1.7   0.5      0.94   2.8e+03      12      39 ..     158     185 ..     146     193 .. 0.64

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.21
       SLIDE 46 nkgkkeyteeeDrfllvllakyGygn..yekik 76
                n++++ ++ eeD  l  l++ ++ g+  ++ i 
  EEA18894.1  2 NRSRNLWSVEEDTTLRRLVESCEKGKvdWRVIA 34
                566677999*****9999999988887788776 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.21
       SLIDE 49 kkeyteeeDrfllvllakyGygnyekikk 77
                   +++ eD+ l + ++++G + + ++ +
  EEA18894.1 59 LGPWSQGEDELLKMGIHRHGPH-WSRVAQ 86
                446999*************987.777765 PP

  == domain 3  score: 7.5 bits;  conditional E-value: 0.0013
       SLIDE  49 kkeyteeeDrfllvllakyGygnyekik 76 
                 ++ +t eeDr ll ++ +yG   ++ i 
  EEA18894.1 110 RSPWTREEDRLLLLAIGEYGRA-WKMIV 136
                 4559***************965.76665 PP

  == domain 4  score: -1.7 bits;  conditional E-value: 0.94
       SLIDE  12 kkieklkelkellkkkveqyknplqelk 39 
                 k+ ++ k  ++ +k  +++ ++p q+++
  EEA18894.1 158 KRKRESKPSTKTTKTTIKKEQQPQQQFT 185
                 3444455556666666777777766654 PP

>> SANT_DAMP1_like  SANT/Myb-like domain of DAMP1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.1      0.19   5.7e+02      29      52 ..       8      34 ..       1      58 [. 0.66
   2 ?   10.8   0.1   0.00014      0.42      24      56 ..     108     140 ..      96     161 .. 0.79

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.19
  SANT_DAMP1_like 29 Wtkeetdy...Lfdlckeydlrfvvia 52
                     W+ ee      L++ c++  + + via
       EEA18894.1  8 WSVEEDTTlrrLVESCEKGKVDWRVIA 34
                     888775550115666677778888887 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00014
  SANT_DAMP1_like  24 lkeedWtkeetdyLfdlckeydlrfvviaDrye 56 
                      + ++ Wt+ee + L+  + ey   + +i D y 
       EEA18894.1 108 IDRSPWTREEDRLLLLAIGEYGRAWKMIVDTYF 140
                      44577**************************95 PP

>> MADF_DNA_bdg  Alcohol dehydrogenase transcription factor Myb/SANT-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.1    0.0055        16      26      51 ..      27      51 ..       7      54 .. 0.83
   2 ?    5.4   0.0    0.0074        22      28      51 ..      80     102 ..      75     105 .. 0.88
   3 ?   -0.4   0.4      0.48   1.4e+03      27      62 ..     130     165 ..     127     184 .. 0.51

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0055
  MADF_DNA_bdg 26 ekaweeiaeel.nekvdveeckkkwkn 51
                  +  w+ ia+ l +   ++++c+k+w++
    EEA18894.1 27 KVDWRVIASYLpG--RNNKDCRKRWHY 51
                  556********55..8999******85 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.0074
  MADF_DNA_bdg  28 aweeiaeelnekvdveeckkkwkn 51 
                    w+++a+ ++ + + ++c k+w+ 
    EEA18894.1  80 HWSRVAQVVG-TRNGDQCFKRWND 102
                   7********9.7999*******85 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 0.48
  MADF_DNA_bdg  27 kaweeiaeelnekvdveeckkkwknLRdryrrelrk 62 
                   +aw+ i++ +    +  + k++ ++L  + +re + 
    EEA18894.1 130 RAWKMIVDTYFPGRTGLDAKNRHRQLTRKRKRESKP 165
                   567777666643344444455444444333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (400 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1104  (0.0615762); expected 358.6 (0.02)
Passed bias filter:                      627  (0.0349713); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 2747.29
//
Query:       EEA18895.1  [L=774]
Description: homoaconitase LysF [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
   6.5e-112  374.9   0.4   6.5e-111  371.6   0.4    2.2  1  Aconitase    Aconitase family (aconitate hydratase)
    1.6e-25   89.9   0.0    2.9e-25   89.1   0.0    1.4  1  Aconitase_C  Aconitase C-terminal domain
  ------ inclusion threshold ------
       0.23   10.5   0.4       0.38    9.8   0.4    1.3  1  MCM          MCM P-loop domain


Domain annotation for each model (and alignments):
>> Aconitase  Aconitase family (aconitate hydratase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  371.6   0.4  1.1e-114  6.5e-111       2     461 .]      66     509 ..      65     509 .. 0.88

  Alignments for each domain:
  == domain 1  score: 371.6 bits;  conditional E-value: 1.1e-114
   Aconitase   2 kiwdahlv.......eeegiayv...pdrvllqdvtgvqalvdlaaareavrrlggtlatidhlvpvdlvidhsvgaeealeknledefernkeryefL 90 
                 ki+++ +v        + g +yv   p+r++++d +++ al+ ++  +++++++++ ++t+dh+v+++                +e    +n ++y+++
  EEA18895.1  66 KIVQKYAVglapgkfVKAG-DYVtisPHRCMTHDNSWPVALKFMSIGASKLHDPNQIVMTLDHDVQNK----------------TE----KNLQKYRQI 143
                 5665555544332221233.444557****************************************99................23....34456**** PP

   Aconitase  91 ksaakafgirvvppgqGIvHqvnlEyglalpgktvvgtDSHTtmigglGvlaiGvGgieaeavllgqplelkipkvvgvkltGklkegvtakDlvlavi 189
                 +++a+++g++++p+g+GI Hq+++E+g+a+pg++vv++DSH++m+gg+G+l++++ +++ ++++++ ++++++p++ +v++tG l++gvt kD+++a++
  EEA18895.1 144 EEFAQHHGVEFYPAGRGIGHQIMVEEGFAWPGTLVVASDSHSNMYGGVGCLGTPIVRTDGASIWATGKTWWQVPNIARVHFTGVLPAGVTGKDVIVALC 242
                 *************************************************************************************************** PP

   Aconitase 190 gklrkkgvvgkvvEffG..egvesLsledraTiaNMaaEvGAttglfpvdektleYLkatgr............eeaavlveaydkaqalf..elaade 272
                 + ++k++v ++++Ef+G  e+++sL ++dr+TiaNM++E+GA +glfp+d+ +  +L+ +              + +a++  ++d+ ++lf  +l+ad+
  EEA18895.1 243 HLFGKDDVLNHAIEFTGseETMRSLRVDDRLTIANMTTEWGALSGLFPIDDVLKGWLRGKATtaamgladgpykT-HAAQRFTHDRLEELFanALTADK 340
                 *****************8889*************************************55545556555543321.11123335667778865699*** PP

   Aconitase 273 daeydkvleldlstlepsvagpkrPqdavplselvkkefkeelekeaaekaleyklkegtklkdgkvdiaaigSCTNssnedvraaaglla.kavekg. 369
                 +a+y+k+l ldls+l+p+v+gp++++ a+p+sel +                          +++kv++a+++SCTNs+ +d+ aaa++++ +a+++g 
  EEA18895.1 341 GAKYAKELFLDLSSLSPYVSGPNSVKVATPISELEA--------------------------QKIKVNKAYLVSCTNSRASDIAAAARVFReAAEANGg 413
                 *******************************55443..........................3456*************************87777774 PP

   Aconitase 370 ..lkvkpgvktsvaPGSevvkayleaeGlleiLekaGfevvgagCstCig.nsdrleegeaivsssNRNFegRqg.pntrayLaSPelvvaaAlaG 461
                    k+++gvk+++a++S   ++ +e +G +++L +aG+e + agC++Cig  ++ le+ge+++s+sNRNF+gR+g ++++ayL SPe+v+a+Al+G
  EEA18895.1 414 kvPKIADGVKFYIAAASLPEQQVAEDAGDWQVLLDAGAEALPAGCGPCIGlGTGLLEPGEVGISASNRNFKGRMGsTDAKAYLGSPEVVAASALSG 509
                 4447788*******************************************************************8799999*************98 PP

>> Aconitase_C  Aconitase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.1   0.0   4.9e-29   2.9e-25       6     130 ..     572     702 ..     567     703 .. 0.93

  Alignments for each domain:
  == domain 1  score: 89.1 bits;  conditional E-value: 4.9e-29
                  CCTT--CHHHHSTGGGCCGHCCHHHCCCGGTTTCCCCTTTSBBSEEEETTTTEEE.......EHHHHHHHHHHTT--EEEE--SSBTBS---THHHHH CS
  Aconitase_C   6 klkGlttedeksnvdtdlkipkqfegtianiglgnelveekrankttdlddgeke.......dvvdaaerykkegaklvviagknfGeGSSRehAAka 96 
                  +++  ++ed +s  +   ++p  ++g+i+ ++++n+++++++++k+t++d+++ e       +++d  +    ++ +++v++ +nfG+GSSRe+AA+a
   EEA18895.1 572 QESEEKQEDAASLTELYPGFPERISGEIVFCDADNINTDGIYPGKYTYQDNVPVEtmaqvcmSNYDPSFADVAKEGDILVSG-FNFGCGSSREQAATA 668
                  5556677888888999999*********************************9999999999999999999999********.*************** PP

                  HHHTTEEEEEES-B-HHHHHHHHHTT-EEEEEST CS
  Aconitase_C  97 lrllGikaviaeSFerIfennliknglLplefke 130
                   +++ i +v+++SF++If++n+i+n+l+ le+++
   EEA18895.1 669 ILAKKIPLVVSGSFGNIFSRNSINNALMGLEVPR 702
                  ******************************9875 PP

>> MCM  MCM P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.4   6.4e-05      0.38     145     175 ..     374     404 ..     363     411 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 6.4e-05
                 HHHSEEEEESSSCEEEEE--EEEEEEE--SS CS
         MCM 145 mEqqtisiaKaGivatLnartsvlaAanpka 175
                 +E q+i+++Ka +v + n+r+s +aAa  ++
  EEA18895.1 374 LEAQKIKVNKAYLVSCTNSRASDIAAAARVF 404
                 8*************************97665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (774 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       622  (0.0346924); expected 358.6 (0.02)
Passed bias filter:                      576  (0.0321267); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.72u 0.30s 00:00:01.02 Elapsed: 00:00:00.46
# Mc/sec: 5088.78
//
Query:       EEA18896.1  [L=376]
Description: cytochrome c mitochondrial import factor (Cyc2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.8e-08   34.0   0.0      7e-08   32.7   0.0    1.7  2  FAD_binding_6  Oxidoreductase FAD-binding domain
    3.4e-07   30.9   0.0    0.00068   20.3   0.0    2.3  2  NAD_binding_1  Oxidoreductase NAD-binding domain
     0.0093   16.1   0.0      0.019   15.1   0.0    1.5  1  NAD_binding_6  Ferric reductase NAD binding domain


Domain annotation for each model (and alignments):
>> FAD_binding_6  Oxidoreductase FAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.7   0.0   1.2e-11     7e-08       3      96 ..      82     184 ..      80     187 .. 0.79
   2 ?   -3.2   0.0       1.9   1.1e+04      85      99 .]     328     342 ..     320     342 .. 0.81

  Alignments for each domain:
  == domain 1  score: 32.7 bits;  conditional E-value: 1.2e-11
                    EEEEEEECCTTEEEEEE.....EESTTTS-----TT-EEEEEECETTCCEEEEEE.B.....SSTTECCEEEEEEE--TT-HHHHHHHCS-TT-EE CS
  FAD_binding_6   3 kltekeevsedtrifrf.....klpsekqklglpvGqhvflrlkikgeaviRsYtpi.....ssenekGelellvkvypgGkmsqaLdelkigdtl 88 
                    kl+++e+vs+  +if++     + ++e+ ++   +G +  + +k ++ ++ R Ytp+     +se++k  l +l+++ p+G++s +L+ l+ g ++
     EEA18896.1  82 KLVSREQVSSTNSIFTLepaasADNHETYEIAWQAGVW-SVMFKQPQLQIGRDYTPLppvddASEDAKESLRFLIRRDPHGEVSRYLHGLQQGASI 176
                    7999*************443222346666788888985.4555558889******98443334557999*************************** PP

                    EEEEEE-S CS
  FAD_binding_6  89 eikGPlGk 96 
                    e++GP+ +
     EEA18896.1 177 EMRGPQIE 184
                    *****865 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 1.9
                    T-EEEEEEEE-SEEC CS
  FAD_binding_6  85 gdtleikGPlGkfeY 99 
                     +++ i+GP G ++Y
     EEA18896.1 328 KKMIIISGPEGFINY 342
                    567899999998877 PP

>> NAD_binding_1  Oxidoreductase NAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0   1.1e-07   0.00068       1      40 [.     196     237 ..     196     240 .. 0.89
   2 !    8.5   0.0   0.00053       3.1      38     107 ..     277     343 ..     249     345 .. 0.75

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 1.1e-07
                    EEEEGGGGHHHHHHHHHHHHH..CTTCSEEEEEEEESSGCGS CS
  NAD_binding_1   1 miagGtGiaPvrsvlrailee..akdktkvvlvyGnrteedl 40 
                    +iagGtGiaP ++    i+++  + ++ k++++++nr++ed 
     EEA18896.1 196 FIAGGTGIAPALQAAYIIFRRpvEGRTPKIHILWANRKREDC 237
                    7*******************96334899**********9985 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00053
                    CGSTTHHHHHHHHHHCTTEEEEEEEESSCTTTSSSEESSHHHHHHHHHHHHSSTTEEEEEECSHHHHHHH CS
  NAD_binding_1  38 edllyreeleelakklpgrlkvvavvsreeagweggkgrvqdalleellslkkeethvyvCGppgMikav 107
                    ++ ++  el++l++++p+++ v ++v +ee     ++  +++ + + + s +  + ++++ Gp+g+i+++
     EEA18896.1 277 KQNAIVRELQALKTRYPRQISVDYFV-DEEH-TFISTKEIKAYI-DSIQSSPGTKKMIIISGPEGFINYM 343
                    44456689**********99888883.3333.335666666555.5555578999***********9976 PP

>> NAD_binding_6  Ferric reductase NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   3.2e-06     0.019       3      48 ..     193     236 ..     191     239 .. 0.93

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 3.2e-06
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  NAD_binding_6   3 nvllvagGiGitpfisilkdllkkskkealktkkikliwvvresss 48 
                     +l++agG+Gi+p++  +  ++++    + +t+ki++ w++r++++
     EEA18896.1 193 DILFIAGGTGIAPALQAAYIIFRRPV--EGRTPKIHILWANRKRED 236
                    689**********************9..99************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (376 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       428  (0.0238719); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.26s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2464.87
//
Query:       EEA18897.1  [L=611]
Description: amino acid transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      2e-61  208.1  45.7    2.6e-61  207.8  45.7    1.1  1  AA_permease_2  Amino acid permease
    2.4e-24   85.8  28.1    2.4e-24   85.8  28.1    2.1  2  AA_permease    Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  207.8  45.7   2.9e-65   2.6e-61       2     400 ..     129     568 ..     128     595 .. 0.85

  Alignments for each domain:
  == domain 1  score: 207.8 bits;  conditional E-value: 2.9e-65
  AA_permease_2   2 sllsafalvigsvigsgifvkn.....laasggpalilwvwiavligslavllvyaElssalprsgGiyvytkaafgkkvaflsawfnwfayvpvl 92 
                    ++l  + l++g++igsgif ++     +a+s+g+ali+w + + l++  ++++ yaEl++a+p +gG   y++++fg+ v+fl+aw++ f   p+ 
     EEA18897.1 129 TYLNGLSLIVGLIIGSGIFSSPsqvnfNAGSPGAALIVWAVAGFLAW--TGAASYAELGGAIPLNGGPQAYLSKIFGEIVGFLFAWCAIFVLKPGS 222
                    56777899*****************999999******9999988886..8********888********************************988 PP

  AA_permease_2  93 asi.lsvaasyllnalgp.dlqg.ntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfssl....stetdt 181
                    a+i ++++++yl+ a+ + ++++ ++w+ ++++ a +++++++n+ ++k    +  i + +k+ + l+ + i+g+i++  g++s       +++++
     EEA18897.1 223 AAIiAIIFGEYLVRAFIGsEVETiSPWINKGVGLAGVLFITILNCASTKLATLVGDISMFFKF-GALLAVTIIGVIVAITGISSKGeanqDWKNSS 317
                    7772577*****99985435544469*************************************.688888889***99999998667755555555 PP

  AA_permease_2 182 ffpngwp.gv..llgllivlwsfdGfesaanvseevkk..kdvpkaifigllivlvlyllvniaflgvvpddeianlsnlgsvaalffeavggkvv 272
                    +f ++++ ++  +++l++ lw+fdG+++ ++v+ e k+  +d+p+ai  ++ +v+v+yl  n+++++v+p+ +i+++++   va  f ++v+g+v+
     EEA18897.1 318 WFEGTSTdISdwAVALYAGLWAFDGWDNTNYVTGEFKNpsRDLPRAIHTAMPVVIVCYLMANVSYFFVLPQATISKSNT---VAVQFGAKVFGPVG 410
                    888866634366889********************887779**********************************9776...69************ PP

  AA_permease_2 273 aiivvilialsllgaintavigssrvlealardgvlPrffakv....................nkfgs...............piraiiltaivsl 333
                    a i+++++  s+lga+n+ +++s r+++a++++g+lP  f k+                    +                   p++a+ ++  ++ 
     EEA18897.1 411 ALILALVVSSSCLGALNATCFTSGRLVYAAGKEGYLPAIFGKIgfgnssnnmtgsrlqrrswfH---KtfswlcggsaaigytPVNAMLFNSALT- 502
                    *************************************999999777777655555555555440...0455555555555666999999999998. PP

  AA_permease_2 334 illllfllassaaynfllsvsslgliisyllliigalilrkkrphlkrpgk..ilvaiigalfllfll..v 400
                    i ++++       + +l + + ++ + +y+l+++g+++lr+++phl+rp+k  i++ ii+++++lfll  +
     EEA18897.1 503 IAYVVV-----GEFGTLITFYGVAGYTFYFLTVLGLIVLRIREPHLERPYKtwITTPIIFCCVSLFLLsrA 568
                    777655.....3699*********************************88875588899999999998551 PP

>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.8  28.1   2.7e-28   2.4e-24       6     332 ..     137     454 ..     133     458 .. 0.83
   2 ?   -0.5   6.1      0.04   3.6e+02     336     417 ..     490     566 ..     488     595 .. 0.79

  Alignments for each domain:
  == domain 1  score: 85.8 bits;  conditional E-value: 2.7e-28
  AA_permease   6 alggviGtglfvglgvvlsqaG.plgallayllagvviflvmlslgeiatngpksggfytyasrflgpelGfviGln..ylfswitvlaleltaasil 100
                   +g +iG g+f + + v  +aG p++al+++++ag+  +  + s +e+  ++p +gg ++y s+  g+ +Gf  ++   +    ++  + + ++a+i+
   EEA18897.1 137 IVGLIIGSGIFSSPSQVNFNAGsPGAALIVWAVAGFLAWTGAASYAELGGAIPLNGGPQAYLSKIFGEIVGFLFAWCaiF----VLKPGSAAIIAIIF 230
                  5899*********88887777637777*************************************************9442....33333333333333 PP

  AA_permease 101 iqfwelvtdlpkawvt..........gavflvvlliinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkgagfrflgdngsifknnlpp 188
                   +++  v++ +  +v           g+  +++++i+n ++ k+   +  i +++k+ a++a+ i+g+i+ + g  +kg  +   ++n+s    ++ +
   EEA18897.1 231 GEYL--VRAFIGSEVEtispwinkgvGLAGVLFITILNCASTKLATLVGDISMFFKFGALLAVTIIGVIVAITGISSKG-EANQDWKNSS----WFEG 321
                  3333..4444433332444456699988899999999999999999999999999999999999999777666666777.4445566666....3444 PP

  AA_permease 189 gfakeeegafknfisvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasaaspfvifikesgvs 286
                        +  ++++++++ + + af+G  ++ ++ gE k+P++++P+ai  ++  +++ Y+++ +++ +++p    +  n +       v f+ +   +
   EEA18897.1 322 T-----STDISDWAVALYAGLWAFDGWDNTNYVTGEFKNPSRDLPRAIHTAMPVVIVCYLMANVSYFFVLPQATISKSNTV------AVQFGAKVFGP 408
                  4.....5668*************************************************************9997777733......4789999999* PP

  AA_permease 287 vlaplinaviltaalssansslysasRvlyslakdglaPkvlkkvs 332
                  v a ++++v+ +++l+++n+  +++ R++y+  k+g++P++++k++
   EEA18897.1 409 VGALILALVVSSSCLGALNATCFTSGRLVYAAGKEGYLPAIFGKIG 454
                  *****************************************99875 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.04
  AA_permease 336 vPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliilsylrfRkalkyqgrsieelgfkaallplgvil 417
                   P++a+l+ +++  + +++ ++ +    ++ + +a +++++l v++li l +     + + ++ +i   +++ ++++l++ +
   EEA18897.1 490 TPVNAMLFNSALTIAYVVVGEFGTL---ITFYGVAGYTFYFLTVLGLIVLRIREPHLE-RPYKTWI-TTPIIFCCVSLFLLS 566
                  6************************...888899**************9988866666.4455555.577777777777655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (611 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       704  (0.039266); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.33s 00:00:00.95 Elapsed: 00:00:00.50
# Mc/sec: 3701.31
//
Query:       EEA18898.1  [L=996]
Description: leucyl-tRNA synthetase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-54  185.7   0.0    4.6e-35  121.0   0.0    6.2  3  tRNA-synt_1    tRNA synthetases class I (I, L, M and V)
    3.5e-41  140.8   0.0    5.3e-41  140.2   0.0    1.3  1  tRNA-synt_1_2  Leucyl-tRNA synthetase, Domain 2
    1.4e-28   99.8   0.2    2.5e-21   75.9   0.0    4.5  5  tRNA-synt_1g   tRNA synthetases class I (M)
    5.4e-12   45.9   0.0    1.1e-11   44.9   0.0    1.5  1  Anticodon_1    Anticodon-binding domain of tRNA
     0.0084   15.1   0.0      0.014   14.3   0.0    1.2  1  tRNA-synt_1d   tRNA synthetases class I (R)
  ------ inclusion threshold ------
      0.049   13.0   0.0        2.5    7.3   0.0    2.2  2  tRNA-synt_1e   tRNA synthetases class I (C) catalytic domain


Domain annotation for each model (and alignments):
>> tRNA-synt_1  tRNA synthetases class I (I, L, M and V)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.0   0.0   1.5e-38   4.6e-35      19     353 ..      91     488 ..      83     495 .. 0.82
   2 !   30.6   0.0   3.4e-11     1e-07     417     527 ..     496     615 ..     491     667 .. 0.68
   3 !   20.9   0.0     3e-08     9e-05     562     596 ..     704     739 ..     697     745 .. 0.85

  Alignments for each domain:
  == domain 1  score: 121.0 bits;  conditional E-value: 1.5e-38
  tRNA-synt_1  19 ekekkefilvdgPPyvtGslHiGhalaktlkdivirykrmkGkevlyvpGwDhaGlaieak.vekklgakekkerkklgreefrekvrewkaeyaeei 115
                  +++ k++il    Py  G++H+Gh    t+ d++ r+++m+G++vl+ +GwD  Gl+ e + +e+ +                  +  ew  + +e++
   EEA18898.1  91 NDRPKSYIL-SMFPYPSGTMHMGHLRVYTISDVLSRFYKMRGHDVLHPIGWDAFGLPAENAaIERGV------------------QPAEWTVQNIERM 169
                  333445555.5568*******************************************9964155543..................235899999**** PP

  tRNA-synt_1 116 rkqvkrlGvsvDfdreylTldkeleeavkevfvrladkgliyrgkklvnwstklktalselEveykdkk............................. 184
                  + q++ +G  +D++re +T ++e+ + ++++f  l++kgl y+++ lvn+++  kt+l++  v+ +  +                             
   EEA18898.1 170 KVQLRSFGPGFDWERELMTCSPEFYKHTQRIFLMLYEKGLAYQAEALVNYDPVDKTVLANEQVDANGFSwrsgakveqlklkqwffritafkeellkd 267
                  ************************************************************999888888999************************** PP

  tRNA-synt_1 185 ........................dalihvafpladkeevklviaTTtPeTllgdtavavnpeldyv....itke.klilaeallkslvkkesekkil 253
                                          +a i++a   +++++  +++ TT+P T+ g   +a+  +   v    +++     ++e   +  ++ ++ ++++
   EEA18898.1 268 ldslsggwpervlsmqrnwlgksdGAKIKFAVTSKHSDNRDVEVFTTRPDTMYGVEYIALSLDHPLVqettKSDPgLKAFLEETASLPADSKVGYRLK 365
                  ********************995555555555556777789********************9988887533122202233333333334444667999 PP

  tRNA-synt_1 254 edergkeLegkevelplvnrkipiiaddyvdkeaGtGvVkiaPahdedDyevgkkynl..........evinildedgtlteea.............. 327
                  + +  + L+    e p   r++p+ +  yv +  G G+V   P+hd+ D +  k+ nl          +       +  ++e+               
   EEA18898.1 366 DVYASNPLQVIDKESPHISRELPVFVAPYVLSSYGEGAVMGVPGHDTRDLAFFKE-NLqpefipvviqP-------EPSVQEDSalvlahdakaftne 455
                  9999999******************************************998765.5657544545550.......4555544445555555666666 PP

  tRNA-synt_1 328 .......aefeglkvfdarkkvveelkekglll 353
                          +++gl+ ++a k+++ +l++ g+  
   EEA18898.1 456 gyltsrcWKYQGLSSKEAAKQIITDLEKIGRGE 488
                  6666666********************998755 PP

  == domain 2  score: 30.6 bits;  conditional E-value: 3.4e-11
  tRNA-synt_1 417 qdWciSRqrwWGhriplfvsketeevvvreelkelva....greeeeaekkalekeakdkl....kkekgelekdedvlDvWFsSgswpfstlgypee 506
                  +dW iSRqr+WG++ip+    + + v v  +   ++     g+  ++++ + le+ a d l     k +g  ++d+d++D+  +S+   +  l+ p++
   EEA18898.1 496 RDWLISRQRYWGTPIPMIHCTNCGPVPVPVDQLPVKLpeigGEWFKAQKGNPLESAADDWLhtecPKCHGPAKRDTDTMDTFVDSSWYYMRYLD-PKN 592
                  8**********************9998755443333211113334444445555555666677655667999*************999999999.999 PP

  tRNA-synt_1 507 dteelkkff..padmlleGlDii 527
                  ++e ++ ++  p d+++ G+   
   EEA18898.1 593 HNEPFSPAVarPVDIYIGGVEHA 615
                  89999865433889999998754 PP

  == domain 3  score: 20.9 bits;  conditional E-value: 3e-08
  tRNA-synt_1 562 rKmSKslgNvidpldvikkygadalRltli.lsdvg 596
                   KmSKs+ N +dp+  ++kygad  R  ++ +++  
   EEA18898.1 704 EKMSKSKHNGVDPMICVEKYGADTTRAHVLfSAPIA 739
                  5*************************9999455544 PP

>> tRNA-synt_1_2  Leucyl-tRNA synthetase, Domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.2   0.0   1.8e-44   5.3e-41       1     184 [.     284     481 ..     284     482 .. 0.81

  Alignments for each domain:
  == domain 1  score: 140.2 bits;  conditional E-value: 1.8e-44
  tRNA-synt_1_2   1 rnWIGrseGleiefkveese...eklevfttrpdtlfGvtfvalapehplveklaekkkelaafieevkkksesereletkekeGv.ftglkaihP 92 
                    rnW+G+s G++i+f+v++++   +++evfttrpdt++Gv+++al+ +hplv++++++++ l+af+ee+++    +       k G+  ++++a +P
     EEA18898.1 284 RNWLGKSDGAKIKFAVTSKHsdnRDVEVFTTRPDTMYGVEYIALSLDHPLVQETTKSDPGLKAFLEETASLPADS-------KVGYrLKDVYASNP 372
                    8***************988522359*****************************************987765544.......66776677777777 PP

  tRNA-synt_1_2  93 it..gek.......ipiwvanyvlmeygtgavmavPahdqrDfeFakkynlp..ikqvikpedee.kklee....seeayteegilvnsg.efdgl 171
                    ++  +++       +p++va yvl++yg gavm+vP+hd+rD++F k+   p  i  vi+pe +  ++ +       +a+t+eg l+    +++gl
     EEA18898.1 373 LQviDKEsphisreLPVFVAPYVLSSYGEGAVMGVPGHDTRDLAFFKENLQPefIPVVIQPEPSVqEDSALvlahDAKAFTNEGYLTSRCwKYQGL 468
                    76432225777777*******************************9886544435567776654422222134448999*****9987656***** PP

  tRNA-synt_1_2 172 kskeakekiakkl 184
                    +skea ++i++ l
     EEA18898.1 469 SSKEAAKQIITDL 481
                    *********9877 PP

>> tRNA-synt_1g  tRNA synthetases class I (M)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.9   0.0   8.3e-25   2.5e-21       2     137 ..      97     234 ..      96     238 .. 0.94
   2 !    7.0   0.0    0.0007       2.1     172     220 ..     241     289 ..     234     303 .. 0.86
   3 ?    2.6   0.0     0.015        45     221     238 ..     494     511 ..     471     518 .. 0.90
   4 ?   -2.9   0.1      0.72   2.2e+03     131     149 ..     552     570 ..     549     576 .. 0.76
   5 !    8.3   0.0   0.00028      0.85     324     362 ..     702     740 ..     698     752 .. 0.83

  Alignments for each domain:
  == domain 1  score: 75.9 bits;  conditional E-value: 8.3e-25
                   EEEE--B--SS---HHHHHHHHHHHHHHHHHHHTT-EEEEEEEE---SHHHHHHHHHTTS-HHHHHHHHHHHHHHHHHHTT---S..EEEETTSHHH CS
  tRNA-synt_1g   2 lvttalpYangklHlGhllevisaDifaRykrlrgeevlfvcgtDehGtpielkAekegvtpeelvekvheeikelfkklnisfd..kygrttseeh 96 
                   ++ + +pY++g++H+Ghl+ + ++D+++R+ ++rg++vl+  g D++G p e +A ++gv+p+e + ++ e++k ++++++  fd      t s e 
    EEA18898.1  97 YILSMFPYPSGTMHMGHLRVYTISDVLSRFYKMRGHDVLHPIGWDAFGLPAENAAIERGVQPAEWTVQNIERMKVQLRSFGPGFDweRELMTCSPEF 193
                   677889***************************************************************************999822345699**** PP

                   HHHHHHHHHHHHHTT-EEEEEEEEEEETTTTEEE-GGG-EE CS
  tRNA-synt_1g  97 kelvqeifkklkekgliyekeieqlycpkderflpdryveg 137
                   ++ +q+if  l+ekgl y+ e  + y+p d++ l++++v+ 
    EEA18898.1 194 YKHTQRIFLMLYEKGLAYQAEALVNYDPVDKTVLANEQVDA 234
                   ************************************99975 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0007
                   .....EEE.EEEEEE-GGGGHHHHHHHH.HH-TTSHHHHHHHH.HHHHT CS
  tRNA-synt_1g 172 sgskpevketehlffklskfekklkewieeeekeleenvkkivkewlke 220
                   sg+k e  + +++ff++ +f+++l + +++ +  ++e+v ++ ++wl +
    EEA18898.1 241 SGAKVEQLKLKQWFFRITAFKEELLKDLDSLSGGWPERVLSMQRNWLGK 289
                   66666666789*****************999999************964 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.015
                   ----EE-ESS-SSS-EET CS
  tRNA-synt_1g 221 gLkdlaisrdldwGipvP 238
                    L+d+ isr+  wG p+P
    EEA18898.1 494 RLRDWLISRQRYWGTPIP 511
                   499**************9 PP

  == domain 4  score: -2.9 bits;  conditional E-value: 0.72
                   -GGG-EE........-TTS CS
  tRNA-synt_1g 131 pdryvegtCPkckseearg 149
                   +d  ++ +CPkc+   +r+
    EEA18898.1 552 ADDWLHTECPKCHGPAKRD 570
                   5778899*****9766554 PP

  == domain 5  score: 8.3 bits;  conditional E-value: 0.00028
                   --------------HHHHHHHH-HHHHHHHHHHHS-TTS CS
  tRNA-synt_1g 324 egkKlSkSrgvvvkakealerldadllRYylaaeapekk 362
                   + +K+SkS++++v++  ++e++ ad+ R  ++ +ap  +
    EEA18898.1 702 SYEKMSKSKHNGVDPMICVEKYGADTTRAHVLFSAPIAE 740
                   568*************************88887777665 PP

>> Anticodon_1  Anticodon-binding domain of tRNA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.9   0.0   3.8e-15   1.1e-11       8     143 ..     812     935 ..     808     943 .. 0.77

  Alignments for each domain:
  == domain 1  score: 44.9 bits;  conditional E-value: 3.8e-15
  Anticodon_1   8 lnklvkevteayee..yrfnkaasalyeffwndlcdwylelvkprlysesaedkraaqevllevletllrllaPfmPfitEelwqr.eeeelgkkesi 102
                  +++++  vt+++e+  y +n+++s+l ++ +n+l      +++       ++++    e+l++++++llrllaP++P +t e+w+  ++e+l++ e i
   EEA18898.1 812 THETIVLVTNCIEKnpYALNTVISDLTKL-TNTL-----SSNR-------PTNP----EILYTCISSLLRLLAPIAPALTSEAWEIlHSELLQDAEAI 892
                  7999*********889************6.6666.....3333.......3344....8*************************66878788888888 PP

  Anticodon_1 103 .mlae.wpekaeelekele....eeevellkeivkairklrselkik 143
                   m    wp ++   ++e++        ++    v++++klr + +i+
   EEA18898.1 893 nMATTtWP-TPILTDTEANalrsRGGQNV---GVQINGKLRFNVTIP 935
                  655557**.66444444422344444444...599999999998887 PP

>> tRNA-synt_1d  tRNA synthetases class I (R)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   4.8e-06     0.014      34      61 ..     108     135 ..      91     145 .. 0.93

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 4.8e-06
                   --BHHHHHHHHHHHHHHHHHHHCT-EEE CS
  tRNA-synt_1d  34 emhvGhLrstiiGdavsrlleflGydvi 61 
                    mh+GhLr   i d++sr + + G+dv+
    EEA18898.1 108 TMHMGHLRVYTISDVLSRFYKMRGHDVL 135
                   7**************************8 PP

>> tRNA-synt_1e  tRNA synthetases class I (C) catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   0.0   0.00085       2.5      22      48 ..     108     134 ..      87     137 .. 0.89
   2 ?    3.0   0.0     0.018        52     248     296 ..     700     749 ..     696     753 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.00085
                   --BHHHHHHHHHHHHHHHHHHHTT-EE CS
  tRNA-synt_1e  22 ashlGhaRslvafDilrrilqalgYdv 48 
                   ++h+Gh R + + D+l r+ +++g+dv
    EEA18898.1 108 TMHMGHLRVYTISDVLSRFYKMRGHDV 134
                   68**********************998 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.018
                   EETTBE--TTTT---BHHHHHTTS-HHHHHH.HHHSS-TTS-EEE-HHHH CS
  tRNA-synt_1e 248 kiegekmsksLknfitikdvlkkfdprqlRl.lllsahyrsqldfkeell 296
                   +i  ekmsks +n +     ++k+ + + R  +l sa   + l+++e+++
    EEA18898.1 700 NISYEKMSKSKHNGVDPMICVEKYGADTTRAhVLFSAPIAEVLEWDETKI 749
                   5788*************9********999972566888999999999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (996 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       475  (0.0264934); expected 358.6 (0.02)
Passed bias filter:                      460  (0.0256568); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.79u 0.31s 00:00:01.10 Elapsed: 00:00:00.53
# Mc/sec: 5701.55
//
Query:       EEA18899.1  [L=232]
Description: endo-1,4-beta-xylanase 1 precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-63  214.0  16.9    1.4e-63  213.7  16.9    1.1  1  Glyco_hydro_11  Glycosyl hydrolases family 11


Domain annotation for each model (and alignments):
>> Glyco_hydro_11  Glycosyl hydrolases family 11
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  213.7  16.9   7.9e-68   1.4e-63       4     177 ..      58     228 ..      55     229 .. 0.94

  Alignments for each domain:
  == domain 1  score: 213.7 bits;  conditional E-value: 7.9e-68
                     -EEEEEECCCSEEEEEC-TTTEEEEEEECSSEEEEEEEESS-TT-EEEEEEEEE.ECCEEEEEEEEEECTTTEEEEEEEEESSS-HHHHSEEEEE CS
  Glyco_hydro_11   4 yyyslwkdgggsvtytngaggsysvswsnagnfvvgkGwnpgskrtikYsgtys.psgnsylavYGWtrnplvEYYivenwgsynpssgatkkgt 97 
                     +y + +++g g+v+y + ++  ++v+w+++++fvvg Gwnpgs++ +++ g++s +sg+++l+vYGWt+nplvEYYi+e+++  +ps  +t+kgt
      EEA18899.1  58 NYNQDYTTG-GTVNYYH-SSTGFQVNWNTQNDFVVGVGWNPGSNSPVNFGGQFSvSSGTGLLSVYGWTTNPLVEYYIIEDYH-NQPS-FGTQKGT 148
                     577889999.9****88.6666********************************6688***********************5.4774.99***** PP

                     EEETTEEEEEEEEEEEEEEETTEEEEEEEEEEEESS--SCEEEEHHHHHHHHHHCT---SEECEEEEEEEEEEEEEEEEE CS
  Glyco_hydro_11  98 vtsdgatYdiykstrvnqpsieGtatfqqywSvrqskrtsgtitvanhfkaWaslGlklgklnyqvlavEgyqssGsasi 177
                     v sdg++Y i+++tr+nqpsi+Gt+tf+qy+Svrqs rt+gt+tv+nhf+aWa+lG++lg +n+qv+avEg+ +sGsas+
      EEA18899.1 149 VYSDGGNYVIWENTRYNQPSIQGTSTFNQYISVRQSPRTQGTVTVQNHFNAWAKLGMNLGAMNFQVIAVEGWGGSGSASY 228
                     *****************************************************************************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (232 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       440  (0.0245412); expected 358.6 (0.02)
Passed bias filter:                      260  (0.0145016); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.32s 00:00:00.76 Elapsed: 00:00:00.48
# Mc/sec: 1461.22
//
Query:       EEA18900.1  [L=70]
Description: hypothetical protein PMAA_011760 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
      0.033   14.8   0.0      0.047   14.2   0.0    1.3  1  BetaGal_dom4_5  Beta-galactosidase jelly roll domain


Domain annotation for each model (and alignments):
>> BetaGal_dom4_5  Beta-galactosidase jelly roll domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   2.6e-06     0.047      81     102 ..      21      42 ..       5      45 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 2.6e-06
  BetaGal_dom4_5  81 phigpqvtFpvpegilnyngen 102
                     ++ig+q+ Fp+pegilny +en
      EEA18900.1  21 NTIGSQLYFPIPEGILNYIEEN 42 
                     89****************9888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (70 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       191  (0.0106531); expected 358.6 (0.02)
Passed bias filter:                      180  (0.0100396); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.35u 0.26s 00:00:00.61 Elapsed: 00:00:00.41
# Mc/sec: 515.86
//
Query:       EEA18901.1  [L=579]
Description: mitochondrial GTPase (Mss1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.1e-33  115.7   1.8    1.7e-24   87.1   1.0    2.4  2  MnmE_helical     MnmE helical domain
    2.3e-21   76.3   0.0      6e-21   74.9   0.0    1.8  1  TrmE_N           GTP-binding protein TrmE N-terminus
    1.5e-17   63.7   0.0    2.9e-17   62.8   0.0    1.5  1  MMR_HSR1         50S ribosome-binding GTPase
    1.3e-07   31.4   0.1    1.5e-05   24.7   0.0    2.4  2  GTP_EFTU         Elongation factor Tu GTP binding domain
    2.7e-05   24.2   0.8     0.0001   22.4   0.2    2.1  2  Glyco_hydro_3_C  Glycosyl hydrolase family 3 C-terminal domai
      3e-05   23.6   0.1    0.00016   21.3   0.1    2.1  1  FeoB_N           Ferrous iron transport protein B
    4.9e-05   23.4   0.2    0.00019   21.5   0.0    2.1  2  Dynamin_N        Dynamin family
    0.00034   20.4   0.0     0.0028   17.4   0.0    2.2  2  AAA_24           AAA domain
  ------ inclusion threshold ------
      0.043   13.7   0.0       0.14   12.0   0.0    1.7  2  Colicin          Colicin pore forming domain
      0.047   13.9   0.0       0.14   12.4   0.0    1.8  1  Roc              Ras of Complex, Roc, domain of DAPkinase
      0.095   12.0   0.0       0.21   10.9   0.0    1.7  1  AIG1             AIG1 family
        0.1   12.5   0.1        1.1    9.2   0.0    2.3  2  RsgA_GTPase      RsgA GTPase


Domain annotation for each model (and alignments):
>> MnmE_helical  MnmE helical domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.1   1.0   1.2e-27   1.7e-24       1     166 [.      98     446 ..      98     463 .. 0.85
   2 !   27.1   0.0   2.8e-09   4.2e-06     166     206 .]     532     576 ..     513     576 .. 0.86

  Alignments for each domain:
  == domain 1  score: 87.1 bits;  conditional E-value: 1.2e-27
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  MnmE_helical   1 LtqaEavadlIdAeteaaakaalrqleGelskkikelrekllellaeleaaiDFpeed.leelsee...elaekleelkeelekllatakrgellre 93 
                   L q+Ea+ +  +Aete+++++a+r ++  ls +++++r++ll ++ elea iDF+e++  +e  +e   +++++++ l+++++ ++++a +gellr+
    EEA18901.1  98 LPQIEALGETLNAETEQQRRLAVRGANNTLSARYEDWRQQLLYARGELEALIDFSEDQhFDESPQElisSVSTQVDVLRQQIRFHIQNASKGELLRN 194
                   679*****************************************************65477777779999*************************** PP

                   xxx.............................................................................................. RF
  MnmE_helical  94 Gik.............................................................................................. 96 
                   Gik                                                                                              
    EEA18901.1 195 GIKiallgapnagkssllnrvvgkeaaivsteegttrdivdvgidlggwyckigdmaglrssknnaerigavelegirrakqralesdvvvvvlsvq 291
                   ************************************************************************************************* PP

                   ...............................................................xxxxxxx......xxxxxxxx.xxxxxxxxx.xx RF
  MnmE_helical  97 ...............................................................Dllkeke......ekeeeevl.kiSaktgeg.ie 122
                                                                                  D+ ++        e+e+++ l +i a    g i+
    EEA18901.1 292 egegaapaqlavdpevleavhacqeygknivvainksdrlpgsanardeatgslvqqvqalfkDVPNSRIfsiscrEAEQSSGLgSITADP--GnIQ 386
                   *********************************9999999999888877777666665555555333333444444222333333344443..3477 PP

                   xxxxxxxx.xx.x...xxxxx..............xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  MnmE_helical 123 eLeeaike.le.l...eeiee..............eplltnaRhkealekalealeeakeale 166
                   ++++ + + +e +   e                  ++l + +R+++ l+++le+le+ + +++
    EEA18901.1 387 TFLRGLISvFEeIarpE---GmqgendmhdisyweDSLGVTHRQQSNLKQCLEHLERFLYETK 446
                   77777777444334442...1333456888999999*******************87665544 PP

  == domain 2  score: 27.1 bits;  conditional E-value: 2.8e-09
                   xxxxxxxxx..xxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxx RF
  MnmE_helical 166 eaglpldlv..aedLrealeaLgeItGe..vvtedlLdeIFskFC 206
                   +a+ + d+v  ae+Lr a+e+L +ItG+   ++ed+L+ +F+kFC
    EEA18901.1 532 NAEPEVDIVtaAENLRFAAESLAQITGRggADVEDVLGVVFEKFC 576
                   34457888888*****************8899************* PP

>> TrmE_N  GTP-binding protein TrmE N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.9   0.0     4e-24     6e-21      45     114 ..       6      94 ..       1      95 [. 0.81

  Alignments for each domain:
  == domain 1  score: 74.9 bits;  conditional E-value: 4e-24
                 EEECT......TCEEE.EEEEEEEBTTCSTTSSEEEEEEEESSHHHHHHHHHHHHCT...............T-EE--CTHHHHHHHHTT CS
      TrmE_N  45 klvdee....ekevlD.evlvlvfkaprsyTgedvvElhlhGgpavvkavleallka...............garlAepGEFtkRaflng 114
                  ++d++     +++lD  +lvl+f++pr++Tgedv+Elh+hGgpa+vkavl+a+ ++                +r+AepGEFt+Raf+n+
  EEA18901.1   6 AIYDPTqapsPNTLLDpGALVLYFPSPRTVTGEDVLELHVHGGPATVKAVLAAI-EKcndviksdednvsssLIRYAEPGEFTRRAFMND 94 
                 4444433444788999999***********************************.3345666667777776459**************96 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.8   0.0   1.9e-20   2.9e-17       1     114 []     197     327 ..     197     327 .. 0.76

  Alignments for each domain:
  == domain 1  score: 62.8 bits;  conditional E-value: 1.9e-20
                 EEEEEESTTSSHHHHHHHHHTS.TEEESSSTTSSSSEEEEEEEETTEEEEEEECGGC......SS..HHHHHHHHHHHHHHHHCTSEEEEEEETT.... CS
    MMR_HSR1   1 evaivGrpNvGKStLinaltge.kaivsdkpgtTrdinegrvklkgkeielvDtpGl......ie..gaseekglgkaflaleeadlillvvdas.... 86 
                 ++a++G pN+GKS+L+n+ +g+ +aivs + gtTrdi+   ++l+g  +++ D++Gl       e  ga e +g+++a ++  e+d++++v++++    
  EEA18901.1 197 KIALLGAPNAGKSSLLNRVVGKeAAIVSTEEGTTRDIVDVGIDLGGWYCKIGDMAGLrssknnAEriGAVELEGIRRAKQRALESDVVVVVLSVQegeg 295
                 69*******************9778******************99999********744444312445666669******************9777655 PP

                 .....TTCSHHHHHHHHHHHHHTTSEEEEEEES CS
    MMR_HSR1  87 .....eeklkpldeeleelleeakkplilvlnk 114
                         ++p+  e     +e +k++++++nk
  EEA18901.1 296 aapaqL-AVDPEVLEAVHACQEYGKNIVVAINK 327
                 554321.23333333333334578888888887 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0     0.016        24       4      35 ..     196     227 ..     193     239 .. 0.80
   2 !   24.7   0.0   9.8e-09   1.5e-05      94     154 ..     281     375 ..     272     489 .. 0.75

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.016
                 EEEEEEESTTSSHHHHHHHHHHHTTSSCHHHH CS
    GTP_EFTU   4 rnigiighvDhGKtTLtdrLlyktgaiskkge 35 
                 ++i+++g  ++GK++L+ r++ k  ai + +e
  EEA18901.1 196 IKIALLGAPNAGKSSLLNRVVGKEAAIVSTEE 227
                 678999***************99888877443 PP

  == domain 2  score: 24.7 bits;  conditional E-value: 9.8e-09
                 -SEEEEEEETTTB.........STHHHHHHHHHHHHTTTEEEEEEESCGST.......HHHHHHHHHHHHHHHHHH..................H CS
    GTP_EFTU  94 lDgavlvvdaveG.........vepqteevlrlalkegvpiivfiNKmDrl.......kaelkeiveevkqklsrk..................e 154
                  D++v+v++++eG         v p   e ++ ++++g +i+v+iNK Drl       ++    +v++v+  ++++                   
  EEA18901.1 281 SDVVVVVLSVQEGegaapaqlaVDPEVLEAVHACQEYGKNIVVAINKSDRLpgsanarDEATGSLVQQVQALFKDVpnsrifsiscreaeqssgL 375
                 79*************************************************88866665556666666665553334444444333333333330 PP

>> Glyco_hydro_3_C  Glycosyl hydrolase family 3 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.4   0.2   6.7e-08    0.0001      19     124 ..     197     330 ..     108     352 .. 0.73
   2 ?   -0.2   0.0      0.53     8e+02      31      59 ..     371     512 ..     357     563 .. 0.60

  Alignments for each domain:
  == domain 1  score: 22.4 bits;  conditional E-value: 6.7e-08
                      EEEEES.GGGSSS-SS-BSSS----S---HHHHHHHHHHH...................................................... CS
                      xxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..................................................... RF
  Glyco_hydro_3_C  19 kiaviG.pnadetlklGggsgtvtvsylvsplegirerles..................................................... 58 
                      kia++G pna                              +                                                     
       EEA18901.1 197 KIALLGaPNAG-----------------------------Kssllnrvvgkeaaivsteegttrdivdvgidlggwyckigdmaglrssknnae 261
                      44444433444.............................033333333444444444444444444477777777777777777777778888 PP

                      .......-HHHHHHHHHHHTSEEEEEEEES...SB-TTSCSGHHSSTTHHHHHHHHHHTTSSEEEEEEESSG CS
                      ......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_3_C  59 ......eegideaveaakeaDvavvvvgedpeiegEgvDrtdlalpeaqdelikavaaanknvvvvlqsggp 124
                             egi++a+++a e+Dv+vvv++ +   egEg   ++la++++  e + a ++ +kn+vv ++++  
       EEA18901.1 262 rigaveLEGIRRAKQRALESDVVVVVLSVQ---EGEGAAPAQLAVDPEVLEAVHACQEYGKNIVVAINKSDR 330
                      899998889*********************...*****************************9999988765 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.53
                      -SS-BSSS----S---HHHHHHHHHHH................................................................... CS
                      xxxxxxxxxxxxxxxxxxxxxxxxxxxx.................................................................. RF
  Glyco_hydro_3_C  31 lklGggsgtvtvsylvsplegirerles.................................................................. 58 
                      + +G gs t+ +  +++ l g+   +e+                                                                  
       EEA18901.1 371 QSSGLGSITADPGNIQTFLRGLISVFEEiarpegmqgendmhdisywedslgvthrqqsnlkqclehlerflyetktsdlrqqqeqpinndttq 464
                      5677777777777777777777777766777777777777777777777777777776666666666666666666666666666666555555 PP

                      ................................................ CS
                      ...............................................x RF
  Glyco_hydro_3_C  59 ...............................................e 59 
                                                                     e
       EEA18901.1 465 svynnpsadanpqvytdtqfhahadagtyahdiqtqaqtpsdaiynpE 512
                      555555555555555555555555555444444444444555555551 PP

>> FeoB_N  Ferrous iron transport protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.1   1.1e-07   0.00016       1      61 [.     196     257 ..     196     342 .. 0.74

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 1.1e-07
                 EEEEEEESTTSSHHHHHHHHHTTSEE.EEESTTSSSEEEEEEEEETTEEEEEEE----SSSS CS
      FeoB_N   1 itvalvGnpnvGkttlfnaltgakqk.vgNwpGvtvekkegklklkgkeveivDlPGiYsls 61 
                 i++al+G pn+Gk++l+n++ g++   v+   G+t +   + ++l g  ++i D+ G  s +
  EEA18901.1 196 IKIALLGAPNAGKSSLLNRVVGKEAAiVSTEEGTTRDIVDVGIDLGGWYCKIGDMAGLRSSK 257
                 589*******************9865267788999999999999999999999999987654 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.0   1.3e-07   0.00019       1      38 [.     198     236 ..     198     296 .. 0.85
   2 ?   -1.6   0.0       1.6   2.4e+03      41      76 ..     426     461 ..     372     488 .. 0.55

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 1.3e-07
                 EEEEEBTTTTHHHHHHHHHTS--S---SS.S---S-EEE CS
   Dynamin_N   1 iavvGsqSsGKSSvlnaLlgedilprgpn.ptTrrplel 38 
                 ia++G+ ++GKSS+ln ++g++   ++++  tTr ++ +
  EEA18901.1 198 IALLGAPNAGKSSLLNRVVGKEAAIVSTEeGTTRDIVDV 236
                 899*******************99987764888888766 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 1.6
                 CCT---CCS...SSEEEE..T-EB--CHHHHHHHHHHH CS
   Dynamin_N  41 geeeeaseravkeelkek..ekkledfsevreeieket 76 
                 +++++   ++  e+l+ +  e+k +d+ + +e+  +  
  EEA18901.1 426 RQQSNL--KQCLEHLERFlyETKTSDLRQQQEQPINND 461
                 333332..233334444444555555544444433333 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.0   1.9e-06    0.0028       2      37 ..     195     231 ..     194     259 .. 0.89
   2 ?    0.0   0.0       0.4     6e+02     106     132 ..     302     328 ..     289     356 .. 0.80

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 1.9e-06
      AAA_24   2 klkiliyGpsgiGKTtlakel.gpkplfidtekGlks 37 
                 ++ki++ G + +GK++l+++  g++++++ te+G+ +
  EEA18901.1 195 GIKIALLGAPNAGKSSLLNRVvGKEAAIVSTEEGTTR 231
                 689*******************************976 PP

  == domain 2  score: 0.0 bits;  conditional E-value: 0.4
      AAA_24 106 elaeefrrllkklqelrknvifiahek 132
                 ++ +e+ +++ + qe++kn+++     
  EEA18901.1 302 AVDPEVLEAVHACQEYGKNIVVAINKS 328
                 57899*************999866555 PP

>> Colicin  Colicin pore forming domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       2.4   3.5e+03      52      74 ..     309     331 ..     306     342 .. 0.87
   2 ?   12.0   0.0   9.3e-05      0.14      50      98 ..     504     552 ..     490     562 .. 0.88

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 2.4
     Colicin  52 dalksfekikrnlnkkikakdrv 74 
                 +a+++ + +++n+   i++ dr 
  EEA18901.1 309 EAVHACQEYGKNIVVAINKSDRL 331
                 89999999************995 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 9.3e-05
     Colicin  50 lsdalksfekikrnlnkkikakdrvaiakalesvdkkilaenleklskg 98 
                  sda+   ek+ +n nkk ++ + +++ +a  +vd    aenl   + +
  EEA18901.1 504 PSDAIYNPEKYSDNGNKKADNSNNTVMFNAEPEVDIVTAAENLRFAAES 552
                 689***************************************9765555 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   9.1e-05      0.14       1      24 [.     197     220 ..     197     237 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 9.1e-05
                 EEEEESSTTSSHHHHHHCHCT-CC CS
         Roc   1 KvvlvGdsgvGKtsllkrfvedkf 24 
                 K+ l+G  ++GK+sll+r+v ++ 
  EEA18901.1 197 KIALLGAPNAGKSSLLNRVVGKEA 220
                 99*****************98765 PP

>> AIG1  AIG1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00014      0.21       2      94 ..     197     291 ..     196     355 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00014
                 EEEEESSTTSSHHHHHHHHHTS--SS--TTTS---SS-EEEEEEETTEEEEEEE--SCCCTTCCHHCH...HHHHHHHHHHCTT-ESEEEEEEETT CS
        AIG1   2 tivlvGktgnGkSaTgNsilgkkaFesklsaqsvtkkcqkksrtwdgkkinViDTPglfdlsvsadki...skeivrclllseegihalllvlslg 94 
                 +i l+G   +GkS+  N ++gk+a   + ++++ t+    +     g   ++ D  gl +++++a++i   + e +r+ +  +   +++++vls++
  EEA18901.1 197 KIALLGAPNAGKSSLLNRVVGKEAAIVS-TEEGTTRDIVDVGIDLGGWYCKIGDMAGLRSSKNNAERIgavELEGIRRAKQRALESDVVVVVLSVQ 291
                 689********************98877.48999******999*******************9999862224566777777777799999999987 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.0   0.00072       1.1      96     125 ..     191     221 ..     148     233 .. 0.73
   2 ?    0.4   0.0      0.36   5.5e+02      38      63 ..     310     335 ..     271     371 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00072
                  HCTT.SEEEEECSTTSSHHHHHHHHCTT--- CS
  RsgA_GTPase  96 llkd.ktsvlvGqSGvGKStLinallpelel 125
                  ll++   ++l+G   +GKS+L+n++++++ +
   EEA18901.1 191 LLRNgIKIALLGAPNAGKSSLLNRVVGKEAA 221
                  45553446899***************98544 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.36
                  HHHHHHHTT-EEEEEEE-GGG--HHH CS
  RsgA_GTPase  38 fLvlaeekgiepvivlnKiDlleeee 63 
                  ++ +++e g ++v+++nK D l  + 
   EEA18901.1 310 AVHACQEYGKNIVVAINKSDRLPGSA 335
                  45667888889999999999887665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (579 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       714  (0.0398237); expected 358.6 (0.02)
Passed bias filter:                      460  (0.0256568); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 3834.24
//
Query:       EEA18902.1  [L=406]
Description: NAD-dependent formate dehydrogenase AciA/Fdh [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      1e-49  168.3   0.0    1.6e-49  167.7   0.0    1.3  1  2-Hacid_dh_C   D-isomer specific 2-hydroxyacid dehydrogenase,
    1.4e-15   57.1   0.0    2.1e-15   56.5   0.0    1.3  1  2-Hacid_dh     D-isomer specific 2-hydroxyacid dehydrogenase,
     0.0026   17.9   0.0     0.0074   16.5   0.0    1.7  2  NAD_binding_2  NAD binding domain of 6-phosphogluconate dehyd
  ------ inclusion threshold ------
      0.031   13.6   0.2       0.55    9.5   0.0    2.2  2  AlaDh_PNT_C    Alanine dehydrogenase/PNT, C-terminal domain
      0.033   12.9   0.0      0.047   12.4   0.0    1.1  1  PROCN          PROCN (NUC071) domain


Domain annotation for each model (and alignments):
>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  167.7   0.0   4.3e-53   1.6e-49       1     177 [.     172     356 ..     172     357 .. 0.92

  Alignments for each domain:
  == domain 1  score: 167.7 bits;  conditional E-value: 4.3e-53
                   HHHHHHHHTTHHHHHHHHHTTCC.HTTCCGSBS-GTTSEEEEES-SHHHHHHHHHHHHTT-.EEEEESSSHHHHHCHHHHTC.EECSHHHHHHH-SE CS
  2-Hacid_dh_C   1 lalllallrrlaeadeevregew.ksekallgkelsgktvGiiGlGrIGqavakrlkafgm.kviaydrskkkeeeeeelgv.elvsleellaesDi 94 
                   ++ +l l+r++  a++++r+g w  +  a   ++l++k vG + +GrIG++v +rlk+f++ ++++yd ++ k e e+e g+ ++++lee+la++D+
    EEA18902.1 172 VMTILTLVRNFVPAHDQIRNGGWdVAAVAKNEYDLENKVVGTVAVGRIGERVLRRLKPFDCkELLYYDYQPLKPEVEKEIGCrRVDTLEEMLAQCDV 268
                   5789*******************8778888999****************************8899*****9999999*****6667*********** PP

                   EEE-S--STTTTTSBSHHHHHCSTTTEEEEESS-GGGB-HHHHHHHHHTTSCCEEEES--SSSSSGTCHHHHHSTT.....EEE-SS- CS
  2-Hacid_dh_C  95 vslhlpltpetrhlinaeelakmkkgailiNtaRGglvdeeaLleaLksgkiagaalDvfeeeplpedspllelpn.....viltPHi 177
                   v++++pl+++t++l+n+e ++kmk+g++l+NtaRG++v +e+++ea+ksg+++g++ Dv+ ++p+p+d+pl+ ++        + PH+
    EEA18902.1 269 VTINCPLHEKTKGLFNKELISKMKPGSWLVNTARGAIVVKEDVAEAVKSGHLRGYGGDVWFPQPAPKDHPLRYVEGpwgggNAMVPHM 356
                   ***********************************************************************76654444445566666 PP

>> 2-Hacid_dh  D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.5   0.0     6e-19   2.1e-15      13     103 ..      76     347 ..      69     387 .. 0.72

  Alignments for each domain:
  == domain 1  score: 56.5 bits;  conditional E-value: 6e-19
                 HHHHHTTE.EEEEES.CSSHHHCHHHHTTESEEEE-TTS..-BSHHHHHHHTT--EEEESSSSCTTB-HHHHHHT..T-EEEE-TTTTHHHHHHHH... CS
                 xxxxxxxx.xxxxxx.xxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxx... RF
  2-Hacid_dh  13 ellkeegv.evevkd.ellteellekakdadalivrsnt..kvtaevlealpkLkviaragvGvDnvDldaaker..GilVtnvpgystesvAElt... 102
                 ++l+++g+  v++ d e ++    +++ da+++i++      +tae l++++kLk+ ++ag+G D+vDl+aa++   Gi+V++v g++  svAE++   
  EEA18902.1  76 KWLEDHGHtLVTTSDkEGPDSVFEKELVDAEVIITTPFHpgYLTAERLAKAKKLKLAVTAGIGSDHVDLNAANKTngGITVAEVTGSNVVSVAEHVvmt 174
                 67788677444444477777788889999******9988778******************************875449******************888 PP

                 ................................................................................................... CS
                 ................................................................................................... RF
  2-Hacid_dh 103 ................................................................................................... 102
                                                                                                                    
  EEA18902.1 175 iltlvrnfvpahdqirnggwdvaavakneydlenkvvgtvavgrigervlrrlkpfdckellyydyqplkpevekeigcrrvdtleemlaqcdvvtinc 273
                 888888888888888888888888888888888887777777777777777777777777777777777777777777777777777777777777777 PP

                 .........................................................................T CS
                 .........................................................................x RF
  2-Hacid_dh 103 .........................................................................a 103
                                                                                          +
  EEA18902.1 274 plhektkglfnkeliskmkpgswlvntargaivvkedvaeavksghlrgyggdvwfpqpapkdhplryvegpwG 347
                 77777777777777777777776655555555555555555555555555555555555555555555555550 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       1.4     5e+03      57      92 ..     127     162 ..      91     185 .. 0.57
   2 !   16.5   0.0   2.1e-06    0.0074       2     106 ..     211     317 ..     210     323 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 1.4
                    SEEEE-SSSHHHHHHHHHSHCCC--TT-EEEE-S-- CS
  NAD_binding_2  57 dvvitmvkagkavdeviegllealkkgdilidgsts 92 
                    ++  + v+ag   d+v  + +++ + g ++ +++ s
     EEA18902.1 127 KKLKLAVTAGIGSDHVDLNAANKTNGGITVAEVTGS 162
                    444444444444444444444444444444333333 PP

  == domain 2  score: 16.5 bits;  conditional E-value: 2.1e-06
                    EEEE--SHHHHHHHHHHHHTT.-EEEEE-SSHHHHHHHHHTTEEE-SSHHHHHHHCSEEEE-SSSHHHHHHHHHS.HCCC--TT-EEEE-S---HH CS
  NAD_binding_2   2 igfiGlGvMGsnmalnllkag.ykvavynrtkekveelvaegakaaesieelvasldvvitmvkagkavdevieg.llealkkgdilidgstsspe 95 
                    +g + +G +G+   ++l+  +  ++  y+ ++ k e   + g++ ++++ee++a++dvv +  +  ++++ + ++ l++++k+g+ l++++  ++ 
     EEA18902.1 211 VGTVAVGRIGERVLRRLKPFDcKELLYYDYQPLKPEVEKEIGCRRVDTLEEMLAQCDVVTINCPLHEKTKGLFNKeLISKMKPGSWLVNTARGAIV 306
                    577788999999999998655157899999999999999999*******************************999*************9999999 PP

                    HHHHHHHHHHH CS
  NAD_binding_2  96 dtrelakelke 106
                      +++a+++k+
     EEA18902.1 307 VKEDVAEAVKS 317
                    99999998876 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.1     0.032   1.1e+02      70     134 ..      81     154 ..      67     185 .. 0.62
   2 ?    9.5   0.0   0.00015      0.55      83     128 ..     257     301 ..     206     312 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.032
                  TTTCECEE..HCHHHHHHHHHHHH-SEEEE---BTTS.S---SC-HHHHHTS-T...TEEEEETTGG...GT-S CS
  AlaDh_PNT_C  70 lgakfvev..lksqeellaeavkeadvvigtvlipGk.kaPkLvteemvksMkp...gsVivDvAid...qGGn 134
                   g++ v++  ++   + +++++ +a+v+i+t   pG  +a +L +++ +k   +   gs  vD+ +    +GG 
   EEA18902.1  81 HGHTLVTTsdKEGPDSVFEKELVDAEVIITTPFHPGYlTAERLAKAKKLKLAVTagiGSDHVDLNAAnktNGGI 154
                  555555553233345779999**********9999963566688887777433212266667775553333554 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00015
                  HHHHHHHHH-SEEEE---BTTSS---.SC-HHHHHTS-TTEEEEETT CS
  AlaDh_PNT_C  83 ellaeavkeadvvigtvlipGkkaPk.LvteemvksMkpgsVivDvA 128
                  ++l+e ++++dvv  t+  p ++  k L ++e +++Mkpgs +v  A
   EEA18902.1 257 DTLEEMLAQCDVV--TINCPLHEKTKgLFNKELISKMKPGSWLVNTA 301
                  67899999***98..778886655555**************999766 PP

>> PROCN  PROCN (NUC071) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   1.3e-05     0.047     123     223 ..     141     241 ..     129     254 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 1.3e-05
       PROCN 123 hldynfnlkPtktlttkerkksrl.GnafhlirellrlvkllvdahvqyrlgkidayqladglqyifnhvgqltGiyrykykvmrqirackdlkhviys 220
                 h+d n   k    +t  e   s +   a h++  +l lv+  v ah q+r g  d   +a   + + n v     + r   +v+r+++   d k ++y+
  EEA18902.1 141 HVDLNAANKTNGGITVAEVTGSNVvSVAEHVVMTILTLVRNFVPAHDQIRNGGWDVAAVAKNEYDLENKVVGTVAVGRIGERVLRRLKP-FDCKELLYY 238
                 99999999999999999999887626799*********************************999****99999*************96.478888888 PP

       PROCN 221 rfn 223
                  + 
  EEA18902.1 239 DYQ 241
                 775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (406 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       498  (0.0277762); expected 358.6 (0.02)
Passed bias filter:                      448  (0.0249875); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2797.93
//
Query:       EEA18903.1  [L=363]
Description: NAD-dependent formate dehydrogenase AciA/Fdh [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.7e-50  168.7   0.0    1.2e-49  168.1   0.0    1.3  1  2-Hacid_dh_C   D-isomer specific 2-hydroxyacid dehydrogenase,
      1e-15   57.6   0.0    1.4e-15   57.1   0.0    1.3  1  2-Hacid_dh     D-isomer specific 2-hydroxyacid dehydrogenase,
      0.002   18.3   0.0      0.006   16.8   0.0    1.7  2  NAD_binding_2  NAD binding domain of 6-phosphogluconate dehyd
  ------ inclusion threshold ------
      0.023   14.0   0.2       0.45    9.8   0.0    2.2  2  AlaDh_PNT_C    Alanine dehydrogenase/PNT, C-terminal domain
      0.027   13.2   0.0      0.038   12.7   0.0    1.1  1  PROCN          PROCN (NUC071) domain


Domain annotation for each model (and alignments):
>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  168.1   0.0   3.3e-53   1.2e-49       1     177 [.     129     313 ..     129     314 .. 0.92

  Alignments for each domain:
  == domain 1  score: 168.1 bits;  conditional E-value: 3.3e-53
                   HHHHHHHHTTHHHHHHHHHTTCC.HTTCCGSBS-GTTSEEEEES-SHHHHHHHHHHHHTT-.EEEEESSSHHHHHCHHHHTC.EECSHHHHHHH-SE CS
  2-Hacid_dh_C   1 lalllallrrlaeadeevregew.ksekallgkelsgktvGiiGlGrIGqavakrlkafgm.kviaydrskkkeeeeeelgv.elvsleellaesDi 94 
                   ++ +l l+r++  a++++r+g w  +  a   ++l++k vG + +GrIG++v +rlk+f++ ++++yd ++ k e e+e g+ ++++lee+la++D+
    EEA18903.1 129 VMTILTLVRNFVPAHDQIRNGGWdVAAVAKNEYDLENKVVGTVAVGRIGERVLRRLKPFDCkELLYYDYQPLKPEVEKEIGCrRVDTLEEMLAQCDV 225
                   5789*******************8778888999****************************8899*****9999999*****6667*********** PP

                   EEE-S--STTTTTSBSHHHHHCSTTTEEEEESS-GGGB-HHHHHHHHHTTSCCEEEES--SSSSSGTCHHHHHSTT.....EEE-SS- CS
  2-Hacid_dh_C  95 vslhlpltpetrhlinaeelakmkkgailiNtaRGglvdeeaLleaLksgkiagaalDvfeeeplpedspllelpn.....viltPHi 177
                   v++++pl+++t++l+n+e ++kmk+g++l+NtaRG++v +e+++ea+ksg+++g++ Dv+ ++p+p+d+pl+ ++        + PH+
    EEA18903.1 226 VTINCPLHEKTKGLFNKELISKMKPGSWLVNTARGAIVVKEDVAEAVKSGHLRGYGGDVWFPQPAPKDHPLRYVEGpwgggNAMVPHM 313
                   ***********************************************************************76654444445566666 PP

>> 2-Hacid_dh  D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.1   0.0     4e-19   1.4e-15      13     103 ..      33     315 ..      25     344 .. 0.72

  Alignments for each domain:
  == domain 1  score: 57.1 bits;  conditional E-value: 4e-19
                 HHHHHTTE.EEEEES.CSSHHHCHHHHTTESEEEE-TTS..-BSHHHHHHHTT--EEEESSSSCTTB-HHHHHHT..T-EEEE-TTTTHHHHHHHH... CS
                 xxxxxxxx.xxxxxx.xxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxx... RF
  2-Hacid_dh  13 ellkeegv.evevkd.ellteellekakdadalivrsnt..kvtaevlealpkLkviaragvGvDnvDldaaker..GilVtnvpgystesvAElt... 102
                 ++l+++g+  v++ d e ++    +++ da+++i++      +tae l++++kLk+ ++ag+G D+vDl+aa++   Gi+V++v g++  svAE++   
  EEA18903.1  33 KWLEDHGHtLVTTSDkEGPDSVFEKELVDAEVIITTPFHpgYLTAERLAKAKKLKLAVTAGIGSDHVDLNAANKTngGITVAEVTGSNVVSVAEHVvmt 131
                 67788777444444477777788889999******9998778******************************875449******************888 PP

                 ................................................................................................... CS
                 ................................................................................................... RF
  2-Hacid_dh 103 ................................................................................................... 102
                                                                                                                    
  EEA18903.1 132 iltlvrnfvpahdqirnggwdvaavakneydlenkvvgtvavgrigervlrrlkpfdckellyydyqplkpevekeigcrrvdtleemlaqcdvvtinc 230
                 888888888888888888888888888888888887777777777777777777777777777777777777777777777777777777777777777 PP

                 ....................................................................................T CS
                 ....................................................................................x RF
  2-Hacid_dh 103 ....................................................................................a 103
                                                                                                     +
  EEA18903.1 231 plhektkglfnkeliskmkpgswlvntargaivvkedvaeavksghlrgyggdvwfpqpapkdhplryvegpwgggnamvphmsG 315
                 7777777777777777777777665555555555555555555555555555555555555555555555555555555555544 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0      0.96   3.4e+03      57      92 ..      84     119 ..      39     146 .. 0.60
   2 !   16.8   0.0   1.7e-06     0.006       2     106 ..     168     274 ..     167     280 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.96
                    SEEEE-SSSHHHHHHHHHSHCCC--TT-EEEE-S-- CS
  NAD_binding_2  57 dvvitmvkagkavdeviegllealkkgdilidgsts 92 
                    ++  + v+ag   d+v  + +++ + g ++ +++ s
     EEA18903.1  84 KKLKLAVTAGIGSDHVDLNAANKTNGGITVAEVTGS 119
                    444444444444444444444444444444333333 PP

  == domain 2  score: 16.8 bits;  conditional E-value: 1.7e-06
                    EEEE--SHHHHHHHHHHHHTT.-EEEEE-SSHHHHHHHHHTTEEE-SSHHHHHHHCSEEEE-SSSHHHHHHHHHS.HCCC--TT-EEEE-S---HH CS
  NAD_binding_2   2 igfiGlGvMGsnmalnllkag.ykvavynrtkekveelvaegakaaesieelvasldvvitmvkagkavdevieg.llealkkgdilidgstsspe 95 
                    +g + +G +G+   ++l+  +  ++  y+ ++ k e   + g++ ++++ee++a++dvv +  +  ++++ + ++ l++++k+g+ l++++  ++ 
     EEA18903.1 168 VGTVAVGRIGERVLRRLKPFDcKELLYYDYQPLKPEVEKEIGCRRVDTLEEMLAQCDVVTINCPLHEKTKGLFNKeLISKMKPGSWLVNTARGAIV 263
                    577788999999999998655157899999999999999999*******************************999*************9999999 PP

                    HHHHHHHHHHH CS
  NAD_binding_2  96 dtrelakelke 106
                      +++a+++k+
     EEA18903.1 264 VKEDVAEAVKS 274
                    99999998876 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.1     0.027        97      70     134 ..      38     111 ..      25     142 .. 0.62
   2 ?    9.8   0.0   0.00013      0.45      83     128 ..     214     258 ..     162     270 .. 0.86

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.027
                  TTTCECEE..HCHHHHHHHHHHHH-SEEEE---BTTS.S---SC-HHHHHTS-T...TEEEEETTGG...GT-S CS
  AlaDh_PNT_C  70 lgakfvev..lksqeellaeavkeadvvigtvlipGk.kaPkLvteemvksMkp...gsVivDvAid...qGGn 134
                   g++ v++  ++   + +++++ +a+v+i+t   pG  +a +L +++ +k   +   gs  vD+ +    +GG 
   EEA18903.1  38 HGHTLVTTsdKEGPDSVFEKELVDAEVIITTPFHPGYlTAERLAKAKKLKLAVTagiGSDHVDLNAAnktNGGI 111
                  555555553233345779999**********9999963566688887777433212266677775553333554 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00013
                  HHHHHHHHH-SEEEE---BTTSS---.SC-HHHHHTS-TTEEEEETT CS
  AlaDh_PNT_C  83 ellaeavkeadvvigtvlipGkkaPk.LvteemvksMkpgsVivDvA 128
                  ++l+e ++++dvv  t+  p ++  k L ++e +++Mkpgs +v  A
   EEA18903.1 214 DTLEEMLAQCDVV--TINCPLHEKTKgLFNKELISKMKPGSWLVNTA 258
                  67899999***98..778886655555**************999766 PP

>> PROCN  PROCN (NUC071) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   1.1e-05     0.038     123     223 ..      98     198 ..      86     211 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 1.1e-05
       PROCN 123 hldynfnlkPtktlttkerkksrl.GnafhlirellrlvkllvdahvqyrlgkidayqladglqyifnhvgqltGiyrykykvmrqirackdlkhviys 220
                 h+d n   k    +t  e   s +   a h++  +l lv+  v ah q+r g  d   +a   + + n v     + r   +v+r+++   d k ++y+
  EEA18903.1  98 HVDLNAANKTNGGITVAEVTGSNVvSVAEHVVMTILTLVRNFVPAHDQIRNGGWDVAAVAKNEYDLENKVVGTVAVGRIGERVLRRLKP-FDCKELLYY 195
                 99999999999999999999887626799*********************************999****99999*************96.478888888 PP

       PROCN 221 rfn 223
                  + 
  EEA18903.1 196 DYQ 198
                 775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (363 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       418  (0.0233142); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2516.57
//
Query:       EEA18904.1  [L=328]
Description: TPR domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.8e-12   46.3   0.1    1.8e-11   44.7   0.1    1.8  1  SET       SET domain
  ------ inclusion threshold ------
       0.12   12.7   0.4        0.7   10.2   0.1    2.1  2  TPR_12    Tetratricopeptide repeat
       0.13   12.2   0.0       0.46   10.5   0.0    1.9  1  OmdA      Bacteriocin-protection, YdeI or OmpD-Associated


Domain annotation for each model (and alignments):
>> SET  SET domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.7   0.1     3e-15   1.8e-11       1     168 [.      20     161 ..      20     162 .. 0.69

  Alignments for each domain:
  == domain 1  score: 44.7 bits;  conditional E-value: 3e-15
                 SCEEEESSXBXTTXEEEEEEECCEECHHHHHHHHHH.....HTEEEEEXGGXXGGSXHHHHHHHTTSSHHHHHHHHHHHHHHHHHHTHHHHHHHXTTTS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         SET   1 GrGvfAtedIpkgeficeypeeiiltkdeadksele.....aylfslpeapknlaftkelakasastllqklakdqkqaekedtdaalkasskaesdln 94 
                 G G fA+ +Ip+g+ i  ++e+++l   ++  +e +     + ++sl+            ++ s   l + +++ +kq + ++t    ++         
  EEA18904.1  20 GLGTFAKTNIPRGTRI--LAESCLLKIKCDGDEEPSatailQAFESLS----------PSQQKSYLELHTYACDLDKQILGKQTGQSWEE--------- 97 
                 7899************..9*9999999999999988999996666666..........22222222222222222222222222222222......... PP

                 XXXHCCCCC.HCCCHEEEETEEEEEECCCGTTGGGCEEXSSSSEEEEEEEETTSSEEEEEESSXBXTTEEEEEXT CS
                 xxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         SET  95 askpeagaf.saiagysidaralksgngagplarflNHsCdpNcnltvqnvlrgprvavfAtrdIkkGeEltidY 168
                     +++   +  + y+ ++++  +  g+      +NHsC pN ++++ +  + ++ ++ +++dI++GeEl+i+Y
  EEA18904.1  98 ----LPEIHrEVLSIYTANSFCSIYLLGS-----RFNHSCLPNTTHSYNP--QLDMETFHTIQDISAGEELLITY 161
                 ....2233346677788888888888887.....55********666666..9********************** PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.3   0.00024       1.5      19      75 ..     223     278 ..     217     279 .. 0.90
   2 ?   10.2   0.1   0.00012       0.7       6      54 ..     251     299 ..     246     305 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00024
      TPR_12  19 ydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaia 75 
                  +eAl+l +k  +i+++  G    +++ +++  + +  +lg+ + Al +  + l+++
  EEA18904.1 223 PEEALKLTQKLAAIQKSE-GLVGRELCFSYYYAAKVNTRLGNARMALLWADKGLEVD 278
                 699********9999655.888889**************************999986 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.00012
      TPR_12   6 lnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrl 54 
                 ++  a v +rlg+   Al + +k le+ r   G+dhp++ ttl +  rl
  EEA18904.1 251 YYYAAKVNTRLGNARMALLWADKGLEVDRYCVGEDHPEYTTTLEAFTRL 299
                 55679999*********************************99887666 PP

>> OmdA  Bacteriocin-protection, YdeI or OmpD-Associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   7.8e-05      0.46      17      35 ..      56      74 ..      53      76 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 7.8e-05
        OmdA 17 aakaaFealtpsyrreylr 35
                a  +aFe+l+ps++++yl+
  EEA18904.1 56 AILQAFESLSPSQQKSYLE 74
                56789************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (328 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       645  (0.0359752); expected 358.6 (0.02)
Passed bias filter:                      548  (0.030565); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 2334.17
//
Query:       EEA18905.1  [L=547]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.021   15.4   0.9      0.021   15.4   0.9    2.8  3  DoxX_3    DoxX-like family
       0.43   10.2   4.1       0.22   11.1   1.0    2.2  2  PIRT      Phosphoinositide-interacting protein family
          4    7.9  10.4          5    7.6   0.8    2.7  2  DUF3262   Protein of unknown function (DUF3262)


Domain annotation for each model (and alignments):
>> DoxX_3  DoxX-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   1.7     0.019   1.1e+02       5      63 ..      52     110 ..      48     134 .. 0.79
   2 ?   15.4   0.9   3.6e-06     0.021      40      84 ..     139     183 ..     129     186 .. 0.90
   3 ?   -2.2   0.3       1.1   6.6e+03      61      81 ..     195     215 ..     189     237 .. 0.64

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.019
      DoxX_3   5 lytGlvpkllvpeagelallaaaglgealasllliaggladialGlllllrrkrrlall 63 
                 l++G+v +++  ++ +  +  + g  +++  ++l++ gl+ +++G+ +l+r  +r  ++
  EEA18905.1  52 LAQGMVLVVIQSMQMSPLISMNCGTIGQIVFPALWVVGLVILVFGIETLYRGFQRNGFA 110
                 68899999888888899888999999***********************9988766554 PP

  == domain 2  score: 15.4 bits;  conditional E-value: 3.6e-06
      DoxX_3  40 aggladialGlllllrrkrrlalllqialllayllaatlllpelw 84 
                  + l++ +lGll ++++++  al + ial+++y+l+a++l  +l+
  EEA18905.1 139 RSTLSECSLGLLSIVKPWSDIALGITIALIVFYTLIASILVTQLF 183
                 56789**********************************998886 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 1.1
      DoxX_3  61 alllqialllayllaatlllp 81 
                 a+  ++  l++ ++ +t++lp
  EEA18905.1 195 AATQMVYYLIIATAVFTFFLP 215
                 333344455555666666655 PP

>> PIRT  Phosphoinositide-interacting protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   1.0   3.7e-05      0.22      50     102 ..      42      97 ..      18     101 .. 0.81
   2 ?   -2.5   0.1      0.59   3.5e+03      94     107 ..     122     135 ..     112     145 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 3.7e-05
        PIRT  50 iivlsvGgavfllGvvittlsrnstlk...nkdkevfklsGpaflslGlmllvcGl 102
                 ++ ls  +av+  G+v+  +   ++++    +  ++ +++ pa+  +Gl++lv+G+
  EEA18905.1  42 VLTLSFTAAVLAQGMVLVVIQSMQMSPlisMNCGTIGQIVFPALWVVGLVILVFGI 97 
                 788999*****99988887755555441115666778*****************97 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.59
        PIRT  94 GlmllvcGlvwvpi 107
                  +++l+ Gl ++p 
  EEA18905.1 122 VVIILLTGLTYIPT 135
                 46778888888885 PP

>> DUF3262  Protein of unknown function (DUF3262)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   0.8   0.00084         5      24      71 ..      81     128 ..      71     133 .. 0.83
   2 ?    4.0   3.0     0.011        64      17      75 ..     156     214 ..     153     215 .. 0.94

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.00084
     DUF3262  24 iagillvvllLwaaWalvsvYkgWaeekiseadllslviRavvlllvl 71 
                 +  +l vv l+++++ + + Y+g++++    ++  ++ i  vv++l+ 
  EEA18905.1  81 VFPALWVVGLVILVFGIETLYRGFQRNGFAPRKKMVVYICWVVIILLT 128
                 556788999*******************99998888888888877765 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.011
     DUF3262  17 psalklliagillvvllLwaaWalvsvYkgWaeekiseadllslviRavvlllvlgflf 75 
                 +s+++l i+++l+v+++L+a   + + +++ + + +++ +++++v   ++ + v +f++
  EEA18905.1 156 WSDIALGITIALIVFYTLIASILVTQLFRATGVDTMERVAATQMVYYLIIATAVFTFFL 214
                 68899********************************9999999999999999999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (547 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       792  (0.0441742); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.44
# Mc/sec: 3761.03
//
Query:       EEA18906.1  [L=554]
Description: MBOAT family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.1e-53  180.6   5.6    5.1e-53  180.6   5.6    1.8  2  MBOAT     MBOAT, membrane-bound O-acyltransferase family
  ------ inclusion threshold ------
      0.045   14.2   0.9      0.045   14.2   0.9    1.9  2  DUF983    Protein of unknown function (DUF983)


Domain annotation for each model (and alignments):
>> MBOAT  MBOAT, membrane-bound O-acyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.1      0.54   4.8e+03     155     196 ..      34      73 ..      31      83 .. 0.67
   2 !  180.6   5.6   5.7e-57   5.1e-53      14     345 ..     125     437 ..     115     440 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 0.54
       MBOAT 155 lskicakdftifkmlssaqllmrsvimrilllllllfllifd 196
                 ls++ a  +++ +    ++ +++ +i ++ l+++l+ +  +d
  EEA18906.1  34 LSYPLAAILKRIPDK--DPWKKNVFIIAASLFYFLGLYELWD 73 
                 555555555555554..4677888999999999999888886 PP

  == domain 2  score: 180.6 bits;  conditional E-value: 5.7e-57
       MBOAT  14 llltlalsvltlqlialvlslydgleketeltedvkellklllisyfvvgflelklhslslvfrklasaallsklpslleylgYvffyplllvGPilsy 112
                 +++t + +vl ++l a++++ +dg +  + lt  +k  +                                 ++ p++l+y+gYv+f+p+l+ GP ++y
  EEA18906.1 125 VDITGPQMVLVMKLSAFCWNIHDGRRPDKDLTDAQKYAA--------------------------------IREFPNILDYAGYVLFFPSLFGGPAFDY 191
                 567889999999999999999999999888888888777................................9*************************** PP

       MBOAT 113 seymsfvesplsrllyta..............krnfavalyalflgltylilieyvlskicakdftifkmlssaqllmrsvimrilllllllfllifdf 197
                  +y++++++ l++  + +              +r+ ++al    +g ++ +++ ++ +++++ +   +++++       s+  ri +l++l+ ++ f++
  EEA18906.1 192 VDYRRWLDTTLFEVPPGTdpskvpptrkkrkiPRSGRPALKKMIIGIIWILAFVQLAPQYPFSFYFSDEYST------LSLPRRIWQLHMLGLVTRFKY 284
                 *************9777799************8888888888888888777777777777777666666665......4677899999999999999** PP

       MBOAT 198 lglwlvalgedilsGlgvng.......arldrvadrniygdwenavsfsefwraWNipvhkWLlryvYkplgskkfklnkslatlatFlfsAvwHglal 289
                 +g+w +++g++i+sGlg+ng       ++++r+ ++n +g  e+a+++++++++WN +++ WL++yvY +++  k+k+++++a+latF +sA+wHg+++
  EEA18906.1 285 YGAWSLTEGACIMSGLGYNGfdaktgkVYWNRLENVNPWG-LETAQNTRGYLENWNKNTNHWLRNYVYLRVT-PKGKKPGFRASLATFGTSAIWHGFYP 381
                 ****************************************.******************************7.89************************ PP

       MBOAT 290 gyliwfvlrvllllveklimrlvalsnlkfdrrrailsnvifwlgaflgpslalll 345
                 gy++ f+++ ++++v k ++r v++++l  d+ ++ + ++++++  ++ ++l++++
  EEA18906.1 382 GYYLAFIFASFVQTVAKNFRRYVRPFFLSPDGSKPTAMKPYYDVASWFVTQLIMSF 437
                 ***************************************************99986 PP

>> DUF983  Protein of unknown function (DUF983)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.1         2   1.8e+04      33      44 ..     234     245 ..     229     254 .. 0.56
   2 ?   14.2   0.9     5e-06     0.045      24      84 ..     423     484 ..     415     484 .. 0.86

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 2
      DUF983  33 livghlvvplal 44 
                 +i+g++++ +++
  EEA18906.1 234 MIIGIIWILAFV 245
                 455555555443 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 5e-06
      DUF983  24 ddgPayfvilivghlvvplallvevayepplwvhlliwlpltlllsllll.rplKGalvalq 84 
                  d++ +fv+ +++ + v+ ++l+ ++ ++++w h++ + ++ ++ +++++  p++G+l+a q
  EEA18906.1 423 YDVASWFVTQLIMSFTVAPFVLLSFNGTISVWRHVYFYGVVGVASAMAFFaSPARGYLIAQQ 484
                 59999**9999999999999******************999998776654279*****9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (554 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       536  (0.0298957); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.75u 0.34s 00:00:01.09 Elapsed: 00:00:00.57
# Mc/sec: 2925.24
//
Query:       EEA18907.1  [L=458]
Description: MBOAT family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-53  182.4   5.7    3.4e-53  181.2   5.7    1.5  1  MBOAT     MBOAT, membrane-bound O-acyltransferase family
  ------ inclusion threshold ------
      0.034   14.5   0.9      0.034   14.5   0.9    1.7  2  DUF983    Protein of unknown function (DUF983)


Domain annotation for each model (and alignments):
>> MBOAT  MBOAT, membrane-bound O-acyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  181.2   5.7   3.8e-57   3.4e-53      14     345 ..      29     341 ..      23     344 .. 0.92

  Alignments for each domain:
  == domain 1  score: 181.2 bits;  conditional E-value: 3.8e-57
       MBOAT  14 llltlalsvltlqlialvlslydgleketeltedvkellklllisyfvvgflelklhslslvfrklasaallsklpslleylgYvffyplllvGPilsy 112
                 +++t + +vl ++l a++++ +dg +  + lt  +k  +                                 ++ p++l+y+gYv+f+p+l+ GP ++y
  EEA18907.1  29 VDITGPQMVLVMKLSAFCWNIHDGRRPDKDLTDAQKYAA--------------------------------IREFPNILDYAGYVLFFPSLFGGPAFDY 95 
                 567888999999999999999999999888888888777................................9*************************** PP

       MBOAT 113 seymsfvesplsrllyta..............krnfavalyalflgltylilieyvlskicakdftifkmlssaqllmrsvimrilllllllfllifdf 197
                  +y++++++ l++  + +              +r+ ++al    +g ++ +++ ++ +++++ +   +++++       s+  ri +l++l+ ++ f++
  EEA18907.1  96 VDYRRWLDTTLFEVPPGTdpskvpptrkkrkiPRSGRPALKKMIIGIIWILAFVQLAPQYPFSFYFSDEYST------LSLPRRIWQLHMLGLVTRFKY 188
                 *************9777799************8888888888888888777777777777777666666665......4677899999999999999** PP

       MBOAT 198 lglwlvalgedilsGlgvng.......arldrvadrniygdwenavsfsefwraWNipvhkWLlryvYkplgskkfklnkslatlatFlfsAvwHglal 289
                 +g+w +++g++i+sGlg+ng       ++++r+ ++n +g  e+a+++++++++WN +++ WL++yvY +++  k+k+++++a+latF +sA+wHg+++
  EEA18907.1 189 YGAWSLTEGACIMSGLGYNGfdaktgkVYWNRLENVNPWG-LETAQNTRGYLENWNKNTNHWLRNYVYLRVT-PKGKKPGFRASLATFGTSAIWHGFYP 285
                 ****************************************.******************************7.89************************ PP

       MBOAT 290 gyliwfvlrvllllveklimrlvalsnlkfdrrrailsnvifwlgaflgpslalll 345
                 gy++ f+++ ++++v k ++r v++++l  d+ ++ + ++++++  ++ ++l++++
  EEA18907.1 286 GYYLAFIFASFVQTVAKNFRRYVRPFFLSPDGSKPTAMKPYYDVASWFVTQLIMSF 341
                 ***************************************************99986 PP

>> DUF983  Protein of unknown function (DUF983)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.1       1.5   1.3e+04      33      44 ..     138     149 ..     133     159 .. 0.56
   2 ?   14.5   0.9   3.8e-06     0.034      24      84 ..     327     388 ..     319     388 .. 0.86

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 1.5
      DUF983  33 livghlvvplal 44 
                 +i+g++++ +++
  EEA18907.1 138 MIIGIIWILAFV 149
                 455555555544 PP

  == domain 2  score: 14.5 bits;  conditional E-value: 3.8e-06
      DUF983  24 ddgPayfvilivghlvvplallvevayepplwvhlliwlpltlllsllll.rplKGalvalq 84 
                  d++ +fv+ +++ + v+ ++l+ ++ ++++w h++ + ++ ++ +++++  p++G+l+a q
  EEA18907.1 327 YDVASWFVTQLIMSFTVAPFVLLSFNGTISVWRHVYFYGVVGVASAMAFFaSPARGYLIAQQ 388
                 59999**9999999999999******************999998776654279*****9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (458 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       623  (0.0347482); expected 358.6 (0.02)
Passed bias filter:                      482  (0.0268838); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.75u 0.38s 00:00:01.12 Elapsed: 00:00:00.60
# Mc/sec: 2288.33
//
Query:       EEA18908.1  [L=594]
Description: vacuolar protein sorting-associated protein VpsB [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.5e-135  453.7   0.1   1.8e-135  453.4   0.1    1.0  1  Sec1      Sec1 family


Domain annotation for each model (and alignments):
>> Sec1  Sec1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  453.4   0.1    1e-139  1.8e-135       1     575 []      32     568 ..      32     568 .. 0.82

  Alignments for each domain:
  == domain 1  score: 453.4 bits;  conditional E-value: 1e-139
                 EEEEE-HHHHHHHHTT--HHHHHTTTEEETT..T--S-.....BTTSEEEEEE-S-HHHHHHHHHHHHSS-SBS-EEEEESS---HHHHHHHHH..S.G CS
        Sec1   1 KvLvlDkelskilssvlkvsdlleegVtkieklkkrepskrealphlkaiyflrptkenidrlakdfisarrykeyhifftprlseslleglakade.e 98 
                 K+L+lD e+ +i+s+++++s ll+++V+ +++l  + +++re+++hl++i+f+rp++ +i++l+ d  +a++y+eyh+fft+ + +s le+la+ad+ e
  EEA18908.1  32 KILLLDSETVPIVSTAITQSALLNHEVYLVDRL--D-NQAREKMRHLRCICFVRPSPNSIQLLI-DELRAPKYGEYHLFFTNIIRKSSLERLAEADDhE 126
                 9***************************88888..3.446899*********************.88999**************************879 PP

                 .GGGEEEEE----SEEEETTEEE-S.....TTHHHHSTTG.....GG........--HHHHHHHHHHHHHHH-..--EEEE-TT-HHHHHHHH...... CS
        Sec1  99 vvkkvklkelnldfvplesdlfsln.....pelplsfrdlyldndns.aleeeieslldriakgLlsvllslekkiPiirykgsaasmvakkladelke 191
                 vv+ v+  e+++df+++++dl sln     +         + +n+++ +    ++++l+r+++gL+++ll l kk P iry++  +s +akkla e++ 
  EEA18908.1 127 VVRVVQ--EQFADFIVINPDLCSLNlgfplN-------RIW-SNSPDmW----NSDALQRTTEGLIAMLLAL-KKNPLIRYEK--NSLMAKKLATEVRY 208
                 **9999..****************8665321.......222.1222224....4579***************.99******99..999*********** PP

                 .....HHHHTTT--SS--EEEEE-GGG-SSTTTS---BHHHHHHHHS--BTEEEEEE--SS.SEEEEEE--TT...-TTHHHHTTSBHHHHHHHHHHHH CS
        Sec1 192 kids.kknfesessrqrpvLiIlDRsvDlvtpllhqwTYqaliddllgglnnnnvvleeep.keekeaelvess.sDeffaelrhlnfgevgeklkkea 287
                 ++++ ++ f++ +++++p+L+IlDR++D++tpll+qwTYqa++++l+g ++n++v+l + p ++++ +e+v+s+ +D+f+++++++nfg++g ++k+++
  EEA18908.1 209 QLTQeEQLFNFRKTDTPPILLILDRRDDPITPLLTQWTYQAMVHELIG-IHNGRVDLRNIPdVRPELQEIVLSQdQDPFYKKNMYQNFGDLGGNIKEYV 306
                 ***977777777***********************************8.************************************************** PP

                 HHHHHHHHTTT....-TTHHHHHHHHHH-GGGHHHHHHHHHHHHHHHHHHHHS-HHH.HHHHHHHHHHHHSS--.B--..-HHHHHHHH-TTS-H.HHH CS
        Sec1 288 keyqeenekkrn.gakesiadlkkfvaklpelqeekkklskHtnlaeellkevkkrkldellelEqdlatgesdkkikekkvieeliaddeptseledk 385
                 ++yq+++  +++ +  esiad+k+fv+ +pe++++++++skH++l++el+++v +++l++++elEq+la+++ +++++ + +++ +i+  ++++  e+k
  EEA18908.1 307 EQYQAKT--QSSmSI-ESIADMKRFVEDYPEFRKLSGNVSKHVTLVSELSRRVGEDDLLDVSELEQSLACND-NHASDLR-SLQRIIQL-PSVKA-ENK 398
                 *****99..344344.6*****************************************************73.3555554.67799999.77666.8** PP

                 HHHHHHHHH....-B.-HT--GG....GGHHHH....GGGGG........---.BGGG-------......................---------S.. CS
        Sec1 386 lRLlllyslv.egglkekelkellrelvqsaly....gleylktlrsleklgllkkrkgkksskkkss...............lklikeeedeesnyd. 463
                 +RL++ly ++ e++ +++ l  ll  l   a +     ++++ +l ++         +  ++                     +        +++    
  EEA18908.1 399 IRLVALYGIRyEKQ-PNNALPVLLDLLSA-AGNvpqhEVNIIPKLLAYHH-------SL-QAP----PvaggfsdlfesvslfS-------GARDRFRg 476
                 **********6644.55644444332222.21233231223333332221.......11.111....12222233322222221.......22222224 PP

                 .....TT-.----HHHHHHHHHTTT-S-TTTS-BSS-GGGS--------------------------S-EEEEEEEEEE-HHHHHHHHHHT...TSSSE CS
        Sec1 464 ...lsgvs.ryaPllvrlvealikgkklssespslskkdpsqeesssslrsakktnsaskesaekkkkqrviVffvGGvTysEiralrllskqekknke 558
                    +++v+ ++ P l  ++++lik +kl++ ++++                       + ++++++k+q++iVf++GG+Ty+E++ + ++++++  + +
  EEA18908.1 477 lkgVENVYtQHSPRLEATLQNLIK-GKLRELQYPFL----------------------EGGGHTRDKPQDIIVFMIGGATYEEAKLIAQINASS-PGIR 551
                 444556999***************.99999999874......................45556666789**********************864.789* PP

                 EEEEEEEE--HHHHHH. CS
        Sec1 559 iiigttsilnpksflee 575
                 +++g+t+i+n+++f+ee
  EEA18908.1 552 VVLGATTIHNSTTFFEE 568
                 **************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (594 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       486  (0.0271069); expected 358.6 (0.02)
Passed bias filter:                      425  (0.0237046); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.77u 0.37s 00:00:01.14 Elapsed: 00:00:00.59
# Mc/sec: 3018.52
//
Query:       EEA18909.1  [L=453]
Description: chitinase 3 precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.3e-16   60.5   0.0    3.1e-15   56.7   0.0    2.0  1  Glyco_hydro_18  Glycosyl hydrolases family 18
    2.8e-10   40.0  10.5    2.8e-10   40.0  10.5    2.6  2  CBM_19          Carbohydrate binding domain (family 19)
  ------ inclusion threshold ------
        3.2    7.7  35.6        6.1    6.8  35.6    1.4  1  Mucin           Mucin-like glycoprotein


Domain annotation for each model (and alignments):
>> Glyco_hydro_18  Glycosyl hydrolases family 18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.7   0.0   5.1e-19   3.1e-15       3     228 ..      31     283 ..      29     322 .. 0.62

  Alignments for each domain:
  == domain 1  score: 56.7 bits;  conditional E-value: 5.1e-19
                     EEEEEGGGGGSS.G........C..SHTTTESEEEEEEEEEEE................TTTEEEESSTTHH........HHHHHHHHHH.HHTS CS
                     xxxxxxxxxxxx.x........x..xxxxxxxxxxxxxxxxxx................xxxxxxxxxxxxx........xxxxxxxxxx.xxxx RF
  Glyco_hydro_18   3 vgYysswesygn.n........y..lpsaklthiiyaFakidg................engkvvvsdwedl........gnfeqlkklk.kkkn 61 
                     ++Y+++++  +  +        +   ++ ++++ ++aF+                    +           +         +  q++++  k +n
      EEA18909.1  31 AVYWGQNSFGKPeEeggqkrlgFycEHLPEVDVFMIAFVTSIMrspgelpnvnfanagnN-----------CtqipgterMKCPQIAEDIiKCQN 114
                     677776666654334544433314422555555555665322244554433333322222...........133344433344455555558999 PP

                     TT-EEEEEEEETTT.TTHHHHHHTSHHHHHHHHHHHHHHHHHCT...............-SEEEEEES-TTTSTCHHHHHHHHHHHHHHHHH.HH CS
                     xxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxx...............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xx RF
  Glyco_hydro_18  62 pgvkvllsiGGwtd.ssgfslaastdasrkkfadsvvsllrkyg...............fDGiDidweypggnpedkenytallkelreald.ka 139
                      g+ +l+s+GG+t+ ++gf +      ++++ a  +++l+ + +               +DG+D+d+e  ++    ++n + +++elr  +  + 
      EEA18909.1 115 LGKTILISLGGATYdEGGFPDPP----TARAAALILWQLFGPVNhsshlvdyrpflnavIDGFDLDFE-NQQ----MRNLVPFASELRRLFLtD- 199
                     9************8577999883....34555666888885555555666666888999*********.545....*************66634. PP

                     HHHTSTTCEEEEEEESSHHHHHHHCHHHHHHHHTSEEEEETTTSSSTTSSBE--SS-SSBT..CSSHHHHHHHHHHT.T--GG.GEEEEEESE CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxx.xxxxx.xxxxxxxxx RF
  Glyco_hydro_18 140 kategkkllLsaavpasasdlskgydlpkiakylDyvnvmtYDfhgswdnvtghhaplyda..slnvdeavkeylka.gvpak.klvlGvpfy 228
                          k++lL++a++++++d  + ++l     ++D v+v++Y+ +      ++h +pl ++   +n d+  + ++k  + +++ k+++Gv  +
      EEA18909.1 200 ---PSKTYLLTVAPQCPYPDR-ANNELLIGPVHIDAVFVQFYNNYC----GVNHFSPLAHEqpDFNFDT-WELWAKTiSNNSDvKVFMGVLGS 283
                     ...4699*************3.233444334455********9999....7999****88424555553.35666553333335999999877 PP

>> CBM_19  Carbohydrate binding domain (family 19)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?  -13.9  19.3         3   1.8e+04       1      30 [.     345     372 ..     344     380 .. 0.53
   2 !   40.0  10.5   4.8e-14   2.8e-10       1      58 [.     382     436 ..     382     438 .. 0.91

  Alignments for each domain:
  == domain 1  score: -13.9 bits;  conditional E-value: 3
      CBM_19   1 itttalatassalfsllvanrsCssqskva 30 
                 +ttt+ +t +s     + a    s+    a
  EEA18909.1 345 TTTTSTTTTTSTS--TPPATTTTSTPTPPA 372
                 4666666666654..455555555544444 PP

  == domain 2  score: 40.0 bits;  conditional E-value: 4.8e-14
      CBM_19   1 itttalatassalfsllvanrsCssqskvaCtadGkYavCdyGkWvvasCPsGvvCls 58 
                 ittt+ +tass   +++  +  C +    aC    ++ vC++G Wvv +CP+G +C+ 
  EEA18909.1 382 ITTTTTSTASSTTWPVP--GGPCPTDGVHACAG-NSFGVCNHGSWVVRACPPGLICIQ 436
                 79*********988765..889*********65.69********************97 PP

>> Mucin  Mucin-like glycoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8  35.6     0.001       6.1      47      96 ..     342     395 ..     331     426 .. 0.48

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.001
       Mucin  47 ttttttkppttttttttasttittkttk..attttt..tttttttateaPsdav 96 
                 t+tttt+++tttt t+t  +t+tt t +  atttt+  +t tttt++ a s++ 
  EEA18909.1 342 TPTTTTTSTTTTTSTSTPPATTTTSTPTppATTTTSkeSTITTTTTSTASSTTW 395
                 444444444444444432222222222200222222002333333333444333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (453 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       787  (0.0438954); expected 358.6 (0.02)
Passed bias filter:                      467  (0.0260472); expected 358.6 (0.02)
Passed Vit filter:                        95  (0.00529868); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.74u 0.31s 00:00:01.05 Elapsed: 00:00:00.49
# Mc/sec: 2757.62
//
Query:       EEA18910.1  [L=475]
Description: camp independent regulatory protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.4e-63  214.3   0.0    2.5e-63  213.5   0.0    1.4  1  Gti1_Pac2  Gti1/Pac2 family


Domain annotation for each model (and alignments):
>> Gti1_Pac2  Gti1/Pac2 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  213.5   0.0   1.4e-67   2.5e-63       1     181 []      11     188 ..      11     188 .. 0.84

  Alignments for each domain:
  == domain 1  score: 213.5 bits;  conditional E-value: 1.4e-67
                 SEES---SHHHHHHHHHHHHTTSS---SS---HHHHHHHSSTTEEEEEEHHHH--SS---S--B---EEETTEEEEEB--------------------- CS
   Gti1_Pac2   1 tfkgyiettkdalllieavlegilkrvtrRlkekErkeliksGsvFvfeeeesgikRWTDGvsWSpSrilgnfLvYreldkkrakkkkkkkkkkskest 99 
                 t++gy++tt+dal+l+ea+l+g+l++v+rR++++Er++l++sGsvF++ee++sgikRWTDGv+WSpSrilgnfLvYreldk  +  +kk+  kk +++ 
  EEA18910.1  11 TYHGYVATTQDALILFEACLTGVLPHVPRRPHDRERNHLVRSGSVFIYEENTSGIKRWTDGVTWSPSRILGNFLVYRELDKPFPPGEKKRAMKKGNRRP 109
                 8******************************************************************************99877666555444443333 PP

                 ----------.................----------------------------------EEEEEEEEEETTTEEEEEEE- CS
   Gti1_Pac2 100 kkeesksekasssssesseakessssseskasksskslekdserslvgsltdsykfkkdgLvKkTisvtlkgkelhlisYyk 181
                  ++++  e   +s+s+   a++ s ++  ++    + +++d er+lvgsl+dsy fk++gLvKkT+svt++g ++hl+sYy+
  EEA18910.1 110 VQASRPGEPYPRSDST---AQSYSPTTPGSNFGGDRPQQSDVERALVGSLVDSYGFKDSGLVKKTMSVTVTGITHHLVSYYS 188
                 3333333332222222...34555555445788899999******************************************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (475 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       287  (0.0160076); expected 358.6 (0.02)
Passed bias filter:                      183  (0.0102069); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 3242.82
//
Query:       EEA18911.1  [L=375]
Description: short chain dehydrogenase/reductase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      1e-32  113.2   0.0    1.3e-32  112.8   0.0    1.1  1  adh_short        short chain dehydrogenase
      7e-23   81.4   0.0      9e-23   81.1   0.0    1.1  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    3.3e-10   40.2   0.0      5e-10   39.6   0.0    1.2  1  KR               KR domain
    1.1e-05   25.0   0.1    2.1e-05   24.1   0.1    1.5  1  Epimerase        NAD dependent epimerase/dehydratase family
     0.0073   15.5   0.0     0.0091   15.2   0.0    1.1  1  Polysacc_synt_2  Polysaccharide biosynthesis protein
  ------ inclusion threshold ------
      0.024   13.7   0.0      0.036   13.1   0.0    1.2  1  RmlD_sub_bind    RmlD substrate binding domain
      0.049   13.7   0.0      0.091   12.9   0.0    1.3  1  DapB_N           Dihydrodipicolinate reductase, N-terminus
       0.17   11.4   0.0       0.31   10.6   0.0    1.4  1  NmrA             NmrA-like family


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.8   0.0     6e-36   1.3e-32       4     184 ..      46     226 ..      43     237 .. 0.96

  Alignments for each domain:
  == domain 1  score: 112.8 bits;  conditional E-value: 6e-36
                 EEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCSHHHHH CS
   adh_short   4 lvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfselseeewe 102
                 l+ Ga++ +Gr +ak+ +  +  v++v+r+ e+ +e ++ +  e+++ l + +Dv+ re v++++e+ ++++g++d++ n+ G    g+ ++ ++ +++
  EEA18911.1  46 LIFGATGHMGRSLAKAALLHNDLVAAVGRTFEDSHESMQRMALENENCLGLLCDVRVRETVSEVLERTIAHFGRIDIIANCSGYGVIGACEDQDDYDIR 144
                 899*************************************9999******************************************************* PP

                 HHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSS CS
   adh_short 103 rvievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdT 184
                 + +e+N++g+++++++ lp++ ++++Gr v  sS+ g  +v+g+ +Y+AsK av+gl++s+  e+ + +i+v  + PG v+ 
  EEA18911.1 145 NQFETNFMGTLNIIQLSLPYFRDRRAGRYVIFSSTSGALGVPGLGPYCASKYAVEGLIESMLYEIDSFNIKVALIEPGHVRR 226
                 ******************************************************************************9983 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.1   0.0     4e-26     9e-23       1     188 [.      49     238 ..      49     248 .. 0.92

  Alignments for each domain:
  == domain 1  score: 81.1 bits;  conditional E-value: 4e-26
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGH.HHHHHHHHHHTTSEE.EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHH CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneea.kkrveelaeelgaev.lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreef 95 
                   Ga   +Gr +Aka+  +   v+++ +  e+ +++++++a e ++ + l cDV+ +e+v ++ e++ ++fg++Di+ n+ g+     g +++ ++ ++
    EEA18911.1  49 GATGHMGRSLAKAALLHNDLVAAVGRTFEDsHESMQRMALENENCLgLLCDVRVRETVSEVLERTIAHFGRIDIIANCSGYGVI--GACEDQDDYDI 143
                   5666689999999999999999999998888999****999888878************************************9..*********** PP

                   HHHHHHHTHHHHHHHHHHHHHCTSC..CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTTHHHH CS
  adh_short_C2  96 draldvnlyslfllakaalplmkeg..gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikgfdel 188
                   ++ +++n+ +++++++  lp+++++  g+ v  ss+++  +vp+   y+a+K a+e+l+ ++ +e+ + +i+v  + pg ++ + ++  + + +l
    EEA18911.1 144 RNQFETNFMGTLNIIQLSLPYFRDRraGRYVIFSSTSGALGVPGLGPYCASKYAVEGLIESMLYEIDSFNIKVALIEPGHVRRDDVTTTTTTTKL 238
                   ********************9998889******************************************************99887777666555 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.6   0.0   2.2e-13     5e-10       3     161 ..      45     203 ..      44     213 .. 0.90

  Alignments for each domain:
  == domain 1  score: 39.6 bits;  conditional E-value: 2.2e-13
                 EEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT-- CS
          KR   3 ylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklleemt 101
                  li G++G++G++la+  +  ++  ++ ++R+    eds++ +++++  + ++  + +Dv  ++ v+++le+  a++++i  + ++ g    ++ e+++
  EEA18911.1  45 WLIFGATGHMGRSLAKAALL-HNDLVAAVGRT---FEDSHESMQRMALENENCLGLLCDVRVRETVSEVLERTIAHFGRIDIIANCSGYGVIGACEDQD 139
                 79*************98655.46788999999...45666678888888899999******************************************** PP

                 HHHHHHHHTTTTHHHHHHHHHTTT....S--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHH CS
          KR 102 aedleqvlapKvkGawnLhelled....esldffvlfSSiagllgsagqanYaaaNaflDalae 161
                 + d+++ ++  + G+ n+ +l+ +    ++    v+fSS +g lg +g + Y a    +++l+e
  EEA18911.1 140 DYDIRNQFETNFMGTLNIIQLSLPyfrdRRAGRYVIFSSTSGALGVPGLGPYCASKYAVEGLIE 203
                 *******************986554544999***********************9988888876 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.1   9.3e-09   2.1e-05       2     120 ..      46     184 ..      45     212 .. 0.77

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 9.3e-09
                 EEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC..........EEEE--TT-HHHHHHHHHHH.T-SEEEE--S---HHHHHHSHHHHHH CS
   Epimerase   2 lVtGatGfiGsalvkallekgyevigldrlssasntarledl..........elveldltdrsalerlfkee.qpdavihlAavggvaassedpadfie 89 
                 l+ GatG +G+ l+ka l ++  v ++ r  ++s+++ ++ +            v++  t ++ ler ++ + ++d++ ++ ++g ++a  ++  + i+
  EEA18911.1  46 LIFGATGHMGRSLAKAALLHNDLVAAVGRTFEDSHESMQRMAlenenclgllCDVRVRETVSEVLERTIAHFgRIDIIANCSGYGVIGACEDQDDYDIR 144
                 89****************999777777777555555555544899999884444444445555999999*999********99******9999988765 PP

                 ....HHTHHHHHHHHHHH.....HHTCTEEEEEEEGGGGT CS
   Epimerase  90 ....knlqgtlnlleaar.....kagvkrllflsSsevYG 120
                     +n++gtln+++ +      ++  + ++f s+s   G
  EEA18911.1 145 nqfeTNFMGTLNIIQLSLpyfrdRRAGRYVIFSSTSGALG 184
                 333389**********997777544444777777776666 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   4.1e-06    0.0091       2     116 ..      46     162 ..      45     222 .. 0.80

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 4.1e-06
                      EEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH......-TTEEEE....E--TT-HHHHHHHTT.......T-SEEEE------H CS
  Polysacc_synt_2   2 lvtGagGsiGselvrqilkkkpkkiillerdElklyeiekeleeelkkkklkveivpvigdvrdkerlekaleel.....kvdvvfhaAAlKhV 90 
                      l+ Ga+G +G++l +  l ++     +  + E +  ++++      +++    +++ +++dvr +e+++++le++     ++d++ ++  +  +
       EEA18911.1  46 LIFGATGHMGRSLAKAALLHNDLVAAVGRTFEDSHESMQRMAL---ENE----NCLGLLCDVRVRETVSEVLERTiahfgRIDIIANCSGYGVI 132
                      799*************999988888888888888888888753...332....235789*******9999998754444579************ PP

                      HHHH....HSHHHHHHHHHHHHHHHHHHHH CS
  Polysacc_synt_2  91 Plve....enpleaiktNvlgtenvieaai 116
                       ++e    + + + ++tN +gt n+i+ ++
       EEA18911.1 133 GACEdqddYDIRNQFETNFMGTLNIIQLSL 162
                      ***93333357788999*********9875 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   1.6e-05     0.036       3      75 ..      45     143 ..      43     164 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.6e-05
                    EEEESTTSHHHHHHHHHCTTTSEEEEEE-TT.....................T--TTSHHHHHHHHHHH.....--SEEEE------HHHHHHSHH CS
  RmlD_sub_bind   3 ilvtGanGqlGseLakqlaeeglevlaltre.....................eldltdaeavaellkea.....kpdvvvnaAAytavDkaEseee 72 
                    +l++Ga+G +G+ Lak++  ++  v a++r+                      +d++ +e+v e+l+ +     + d++ n+  y  + ++E++ +
     EEA18911.1  45 WLIFGATGHMGRSLAKAALLHNDLVAAVGRTfedshesmqrmalenenclglLCDVRVRETVSEVLERTiahfgRIDIIANCSGYGVIGACEDQDD 140
                    69***************99999899999999*****************99998899999999888855422223788****************987 PP

                    HHH CS
  RmlD_sub_bind  73 aay 75 
                     + 
     EEA18911.1 141 YDI 143
                    554 PP

>> DapB_N  Dihydrodipicolinate reductase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   4.1e-05     0.091       5      44 ..      47      88 ..      45     118 .. 0.59

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 4.1e-05
                EETTTSHHHHHHHHHHHHSTTEEEEEEEETTC....STTTTTBH CS
      DapB_N  5 vvGasGrmGkevvkaveeaedlelvaavdrke....selegkda 44
                ++Ga+G mG++++ka+  ++d  lvaav r+     ++++ + +
  EEA18911.1 47 IFGATGHMGRSLAKAALLHND--LVAAVGRTFedshESMQRMAL 88
                89*************999665..455555543111034443333 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00014      0.31       2      32 ..      46      76 ..      45      91 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00014
                EESSTTSHHHHHHHHHHHHHT-EEEEEES-S CS
        NmrA  2 lviGaTGrqGksvvrallkaghkvralvRdt 32
                l++GaTG++G+s+++a+l ++  v a+ R  
  EEA18911.1 46 LIFGATGHMGRSLAKAALLHNDLVAAVGRTF 76
                79****************9999999887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (375 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       328  (0.0182944); expected 358.6 (0.02)
Passed bias filter:                      302  (0.0168442); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.68u 0.34s 00:00:01.02 Elapsed: 00:00:00.57
# Mc/sec: 1982.05
//
Query:       EEA18912.1  [L=683]
Description: mitochondrial translation optimization protein (Mto1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.1e-156  521.8   0.0   1.4e-156  521.5   0.0    1.1  1  GIDA           Glucose inhibited division protein A
    4.9e-68  229.4   0.1    7.9e-68  228.8   0.1    1.3  1  GIDA_assoc     GidA associated domain
    6.3e-05   22.3   2.1    0.00022   20.6   2.1    1.8  1  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    8.9e-05   22.0   6.5    9.7e-05   21.9   5.8    1.5  1  FAD_oxidored   FAD dependent oxidoreductase
    0.00068   19.0   0.4     0.0036   16.6   0.2    2.0  2  AlaDh_PNT_C    Alanine dehydrogenase/PNT, C-terminal domain
     0.0011   18.1   3.9     0.0014   17.7   2.5    1.9  2  FAD_binding_2  FAD binding domain
  ------ inclusion threshold ------
      0.011   14.8   0.1      0.023   13.7   0.1    1.5  1  Lycopene_cycl  Lycopene cyclase protein
       0.11   11.6   0.1       0.53    9.4   0.0    2.0  2  K_oxygenase    L-lysine 6-monooxygenase (NADPH-requiring)
       0.12   11.0   2.0       0.41    9.3   0.8    2.3  3  HI0933_like    HI0933-like protein
       0.15   12.1   0.2       0.72    9.8   0.0    2.0  2  NAD_binding_9  FAD-NAD(P)-binding
       0.51    9.9   3.5         11    5.5   0.0    2.4  2  DAO            FAD dependent oxidoreductase


Domain annotation for each model (and alignments):
>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  521.5   0.0  8.7e-160  1.4e-156       1     391 [.      39     440 ..      39     441 .. 0.98

  Alignments for each domain:
  == domain 1  score: 521.5 bits;  conditional E-value: 8.7e-160
                 CEEEE-SSHHHHHHHHHHHHTT--EEEEES-GGGTT--SSSSEEE-TTHHHHHHHHHHHT-SHHHHHHHHEEEEEEESTTS-CCC-EEEEEE-HHHHHH CS
        GIDA   1 dviViGgGhAGceAAlaaarlGakvlLithkldtiaelsCnpsiggiakgllvrEidalggliikaadkagiqfrilNrskGpavralraqvdrelysk 99 
                 dv+V+GgGhAG eA++aaar+Ga+++L+t++ld+i+ +sCnps+ggi+kg+++rEidal+g+ ++++dkag+ fr+lNrskGpav+++raq+dr+ly++
  EEA18912.1  39 DVVVVGGGHAGAEACAAAARSGARTALVTPSLDNIGVCSCNPSFGGIGKGTMMREIDALDGVAGRVIDKAGVMFRVLNRSKGPAVWGPRAQIDRDLYKR 137
                 79************************************************************************************************* PP

                 HHHHHHHTSTTEEEEES-EEEEEECT..........TEEEEEEETTS-EEEECEEEE--TT-BT-EEEETTEEEESSCTTC--B-THHHHHHHTT--EE CS
        GIDA 100 evteklenepnleiieeeveelivee..........kkvkgvvtedgetikakavviatGtflkgkihigekelsaGrlgeltseglseslkelgfell 188
                 +++e+l +++nl+i+e++ve+++v+           +k+ gv++++g++i ++ vvi+tGtfl g+ihig +++++Gr+ge ++++ls+sl++ gf+l+
  EEA18912.1 138 YMQEELVATKNLSIVEAKVEDIVVSRdesdqnphsaGKIVGVRLDSGQVIPTSRVVITTGTFLGGEIHIGLEAYPSGRMGEAATHALSKSLRQAGFQLG 236
                 **********************99889************************************************************************ PP

                 EEEEEE--EEEGGGS-TTTSEEE---SS-B-SSSSSSST...CG----EEEEE--HHHHHHHHCTCCC-T.T----B--S-CCC-SSTCCCCCCSTT-S CS
        GIDA 189 rlktgtppridkesidfskleeqsgdkegeefsylnkpl...nkeqvecfltatneathkiikenlkksaklfegcieelgprycpsiedkivrladke 284
                 rlktgtppr+dk+sidfs+le q gd+++++fs++nk++   ++ q+ c++t+tneath+ii++nl++s+ ++++++   gprycps+e ki+r+++k+
  EEA18912.1 237 RLKTGTPPRLDKKSIDFSSLEVQRGDSPPNPFSFMNKTTqvsDEGQLTCWMTHTNEATHDIIRANLDNSI-HIRETV--RGPRYCPSLEAKILRFKHKK 332
                 *************************************99665599*************************.555565..5******************* PP

                 --EEEEEESSTT--E.EEEET----S-HHHHHHHHTTSTT-TT--EEE--EEEEEEEE-GGGB-TTSBBSSSBTEEE-CGGGTB-SHHHHHHHHHHHHH CS
        GIDA 285 shqvfLepegletel.iylvgfstslpeevqkevlrsipGLenaeivrpGyaieydyvdprqllntLetkkvkgLflAGqinGteGYeEaaaqGllAGi 382
                 +hq++Lepeg + ++ iy++g+s + p+e q+++lr+i GLen+++++p+y +eydy+dpr+l++tLetk + gL+lAGqinGt+GYeEaa+qG+lAG+
  EEA18912.1 333 EHQIWLEPEGFAPNEvIYPNGISMTVPVEAQEAMLRTIRGLENVRMLQPAYGVEYDYIDPRNLKPTLETKLIGGLYLAGQINGTTGYEEAAGQGILAGM 431
                 ***********99988*********************************************************************************** PP

                 HHHHHHCTS CS
        GIDA 383 naarkakgk 391
                 na + a+gk
  EEA18912.1 432 NAGLAAQGK 440
                 ******997 PP

>> GIDA_assoc  GidA associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  228.8   0.1   4.8e-71   7.9e-68       1     207 [.     443     658 ..     443     661 .. 0.96

  Alignments for each domain:
  == domain 1  score: 228.8 bits;  conditional E-value: 4.8e-71
                 ----TTT-HHHHHHHHHHHH--SS-B-CCCB--TTTCCC-CCCHHHHHHHHHHHTTSS-HHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHH...HHH CS
  GIDA_assoc   1 lilkRseaYiGVLiDDLvtkgvkEPYRmfTSRaEyRlllRaDnAdlRLtekgrelGlvseeryekfeekkeeieelkellkstklkseewkkl..lekk 97 
                 ++l+R+++YiG+++DDL+t+gv+EPYRmfTSR+E+R++ R+DnAdlRLt +gre+ +vs+er+++f+e+k++i+el +ll++t+++s++w++l  +++ 
  EEA18912.1 443 MVLTRADGYIGIMVDDLITRGVSEPYRMFTSRSEFRISSRSDNADLRLTAMGREASVVSDERWAHFSETKAQIDELSQLLANTRYTSNQWSRLgfQTRV 541
                 689*****************************************************************************************9999999 PP

                 T....EHHHHCTTST--HHHHHCCHHHH.......HHHSCHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHTSB--TTS-CCCSTT--CHHHHHHHHH-- CS
  GIDA_assoc  98 eskklslaellkrpevkledlleelpee.......eeeseeeleqveieakYegyiekqeeeieklkkeenlkipedldYskikgLskearekLkkvrP 189
                 +++ +s +++l    +++++l+ ++++        ++ ++e +++v+iea+Y++y+++q+  +ek+++ee++ +p+++dYs+++gLs+e+r+ L++vrP
  EEA18912.1 542 DTSYRSGLDMLCVDGIDIDSLIPHITSPsgiaytsASFDPEIKKRVTIEAQYAPYVKRQSLMAEKFRREERMLLPSNMDYSAVHGLSTEERQALERVRP 640
                 99999****************998888799***977888888********************************************************* PP

                 SCHHHHTTSTTS-HHHHH CS
  GIDA_assoc 190 etlgqAsrisGvtpaais 207
                 e++g  +ri+G+tp+  +
  EEA18912.1 641 ENIGMLRRIEGITPSGAV 658
                 **************9765 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.6   2.1   1.4e-07   0.00022       1      31 [.      38      70 ..      38     200 .. 0.55

  Alignments for each domain:
  == domain 1  score: 20.6 bits;  conditional E-value: 1.4e-07
                 CSEEEE--SHHHHHHHHHHHHHTS-EEEEE..T CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..x RF
  Pyr_redox_2  1 kdvvviGgGpAGlaaaltlaqagakvtlve..l 31
                 +dvvv+GgG+AG +a   +a++ga+++lv   l
   EEA18912.1 38 YDVVVVGGGHAGAEACAAAARSGARTALVTpsL 70
                 69***************************6432 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.9   5.8     6e-08   9.7e-05       1      31 [.      39      69 ..      39     198 .. 0.80

  Alignments for each domain:
  == domain 1  score: 21.9 bits;  conditional E-value: 6e-08
  FAD_oxidored  1 DvvVvGGgpaGvaAAiaAaraGakvlLveer 31
                  DvvVvGGg aG  A  aAar+Ga+++Lv ++
    EEA18912.1 39 DVVVVGGGHAGAEACAAAARSGARTALVTPS 69
                  9***************************975 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.2   2.2e-06    0.0036      21      56 ..      30      65 ..      23      73 .. 0.87
   2 ?   -0.5   0.0      0.39   6.4e+02     124     178 ..     176     229 ..     168     243 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 2.2e-06
                 CEETCB---EEEEESTSHHHHHHHHHHHHTT-EEEE CS
  AlaDh_PNT_C 21 GgvpgvepakvlviGgGvaGlqAiatakglgakVtv 56
                 ++ ++v+p  v+v+GgG aG +A a+a++ ga++ +
   EEA18912.1 30 ATSSDVRPYDVVVVGGGHAGAEACAAAARSGARTAL 65
                 4566799************************99865 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.39
                  EEETTGGGT-SBTT--TBBTTSEEEEETTEEEEEBSTGG.GGSHHHHHHHHHHHHH CS
  AlaDh_PNT_C 124 ivDvAidqGGnvetsrltthgepvveekgvvhygvanlp.gavprtasalltnntl 178
                  iv v  d+G  + tsr+   + + +   g +h+g +  p g++ + a+++l++++ 
   EEA18912.1 176 IVGVRLDSGQVIPTSRVVITTGTFLG--GEIHIGLEAYPsGRMGEAATHALSKSLR 229
                  67777788888888887666666655..8899999999956999*******99875 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   2.5   8.9e-07    0.0014       1      29 [.      39      67 ..      39      85 .. 0.92
   2 ?   -2.7   0.0       1.5   2.4e+03     158     202 ..     134     199 ..     114     225 .. 0.50

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 8.9e-07
                   SEEEE--SHHHHHHHHHHHHTTT-EEEEE CS
  FAD_binding_2  1 DviViGsGlAGLaAAleaaeaGlkvavve 29
                   Dv+V+G+G AG  A ++aa+ G+++a+v+
     EEA18912.1 39 DVVVVGGGHAGAEACAAAARSGARTALVT 67
                   9**************************98 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 1.5
                    EEESEEEEEEEECTT......EEEEEEEEET.......TTTCEE........EEEESEEEE----- CS
  FAD_binding_2 158 fqerteadeLivedg......rvtGavvenp.......esgrev........rirakavvlatgGf 202
                    ++ r+  +eL+ +++      +v  +vv+ +       + g++v         i   +vv++tg f
     EEA18912.1 134 LYKRYMQEELVATKNlsiveaKVEDIVVSRDesdqnphSAGKIVgvrldsgqVIPTSRVVITTGTF 199
                    555555555555544433333444444443343333332222223333333122233555555555 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.1   1.4e-05     0.023       1     141 [.      39     198 ..      39     212 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.4e-05
  Lycopene_cycl   1 DvvviGaGpAg...lslAarl.......teakpglkvvlieaspsllfpnnyvWsdefedlga.leecvehsWsgtivylddgkkillgraYgrvs 85 
                    Dvvv+G+G Ag   ++ Aar+       t +  ++ v++ ++s +    ++ + + e  +l++   +++++   + +v    + +   g + +++ 
     EEA18912.1  39 DVVVVGGGHAGaeaCAAAARSgartalvTPSLDNIGVCSCNPSFGG--IGKGTMMREIDALDGvAGRVIDKAGVMFRVLNRSKGPAVWG-PRAQID 131
                    9*********955566777775444443334444555555444444..44556666666776656789999999999999999999999.99**** PP

  Lycopene_cycl  86 skrlkeellerlv.engvklleakvesveeeea.ge.........slvvleggrkirarlvvdargl 141
                    ++  k+ ++e+lv +++ + +eakve ++ + + ++         + v l+ g+ i+ + vv  +g 
     EEA18912.1 132 RDLYKRYMQEELVaTKNLSIVEAKVEDIVVSRDeSDqnphsagkiVGVRLDSGQVIPTSRVVITTGT 198
                    *************999**********99765441111111111113356777777777777777764 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.0   0.00032      0.53     176     216 ..      24      62 ..      17      72 .. 0.79
   2 ?   -1.3   0.0      0.59   9.5e+02      92     158 ..     129     198 ..     126     199 .. 0.66

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00032
  K_oxygenase 176 vHsseylerkeellakkriaVvGsGqSaaeifedllrrqkk 216
                  +H+ +++++   + ++ +++VvG+G  +ae +  ++r+ ++
   EEA18912.1  24 LHKRHLATSS--DVRPYDVVVVGGGHAGAEACAAAARSGAR 62 
                  5555555554..89999***************999988654 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.59
  K_oxygenase  92 lpsRkefedYlrWvasqleeqvrfgeeveevepdeeeee....elltveskdaegeeeelearnlvlgvGt 158
                   + R+ +++Y+++   + ++    +++ve++ ++++e++    ++ ++    + ++ + + + ++v+++Gt
   EEA18912.1 129 QIDRDLYKRYMQEELVATKNLSIVEAKVEDIVVSRDESDqnphSAGKIVG-VRLDSGQVIPTSRVVITTGT 198
                  57799999999998888888666788999988776432222332333332.24566678888888888886 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.8   0.00025      0.41       1      29 [.      38      66 ..      38      71 .. 0.93
   2 ?   -3.5   0.0       1.9   3.1e+03     138     163 ..     172     197 ..     155     198 .. 0.83
   3 ?   -0.5   0.0      0.24   3.9e+02     360     384 ..     385     413 ..     381     420 .. 0.68

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00025
                 -SEEEE--SHHHHHHHHHHHHTT--EEEE CS
  HI0933_like  1 kdviviGgGaAGlmaAisaakrgkrVlll 29
                 +dv+v+GgG AG  a+++aa+ g+r++l+
   EEA18912.1 38 YDVVVVGGGHAGAEACAAAARSGARTALV 66
                 59**********************99986 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 1.9
                  ETTE.EEEEE.TTEEEEESEEEE--- CS
  HI0933_like 138 eedgkfrvktkseeeleadklvlAtG 163
                  ++++++ v+++s++ + ++++v++tG
   EEA18912.1 172 SAGKIVGVRLDSGQVIPTSRVVITTG 197
                  566778899999999*********99 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 0.24
                  E-GGGB-TT....T-BBTTSTTEEE-GGG CS
  HI0933_like 360 Vdlkevssk....tmeskkvpgLffaGEv 384
                  V+ + ++++    t+e+k + gL++aG +
   EEA18912.1 385 VEYDYIDPRnlkpTLETKLIGGLYLAGQI 413
                  5555555542223899***********76 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.1      0.77   1.3e+03       1      19 [.      41      59 ..      20      68 .. 0.77
   2 ?    9.8   0.0   0.00044      0.72      85     155 ..     124     198 ..     111     199 .. 0.68

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.77
  NAD_binding_9  1 aivGaGprGlavlerLlar 19
                   ++vG+G +G+ ++++ +++
     EEA18912.1 41 VVVGGGHAGAEACAAAARS 59
                   5788888888777766655 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00044
  NAD_binding_9  85 ldpddfvpRalyGrYlrdlfeellarl..pegvtvevhraevvdleeradg..qavlladgaslaadaVvLAlGh 155
                    + p++ + R ly rY+++ + +  +    +++v+  v++ +  d +++ +g  + v+l++g+ +   +Vv+++G 
     EEA18912.1 124 WGPRAQIDRDLYKRYMQEELVATKNLSivEAKVEDIVVSRDESDQNPHSAGkiVGVRLDSGQVIPTSRVVITTGT 198
                    56888999********987655443222244443333333333444444443358*******************7 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   1.5     0.021        34       1      26 [.      39      66 ..      39      77 .. 0.85
   2 ?    5.5   0.0    0.0067        11     112     207 ..     101     204 ..      86     234 .. 0.72

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.021
                EEEEECTSHHHHHHHHHHHHTT..EEEE CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..Vtll 26
                dvv++GGG +G+ +  ++ar g  ++l+
  EEA18912.1 39 DVVVVGGGHAGAEACAAAARSGarTALV 66
                9***********9888888888887776 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.0067
                 TEEEEEHHHHHHHSTTSTTTS.EEEEETTEEEEEHHHHHHHHHHH.HHHTT-EEEESECEEEE..EEEE.........TCEEEEEEECTEEEEEEEEEE CS
         DAO 112 daelldaeevrelepalpgll.galfypdtgqvdpakltaalara.aealGveilegtevtgl..eeed.........gkvwgverttpgendaadavV 197
                   +++d++ v+ +   l++ +  a++ p  +q+d   + ++++++ ++++   i+e  +v+++  ++ d         gk++gv r  +g++     vV
  EEA18912.1 101 AGRVIDKAGVMFRV--LNRSKgPAVWGPR-AQIDRDLYKRYMQEElVATKNLSIVEA-KVEDIvvSR-DesdqnphsaGKIVGV-RLDSGQVIPTSRVV 193
                 44666665555444..2333424688889.999************667778999998.****85533.2356778899******.555587744366** PP

                 E--GGGHH.HH CS
         DAO 198 naaGawsd.ll 207
                 +++G + + ++
  EEA18912.1 194 ITTGTFLGgEI 204
                 ****9965544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (683 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       366  (0.0204139); expected 358.6 (0.02)
Passed bias filter:                      345  (0.0192426); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.72u 0.35s 00:00:01.06 Elapsed: 00:00:00.58
# Mc/sec: 3556.40
//
Query:       EEA18913.1  [L=173]
Description: ARD/ARD family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.1e-45  154.7   0.2    2.5e-45  154.5   0.2    1.0  1  ARD           ARD/ARD' family
    6.5e-09   35.4   0.0    1.1e-08   34.7   0.0    1.3  1  Cupin_2       Cupin domain
    0.00012   22.0   0.0    0.00019   21.4   0.0    1.3  1  AraC_binding  AraC-like ligand binding domain


Domain annotation for each model (and alignments):
>> ARD  ARD/ARD' family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  154.5   0.2   4.2e-49   2.5e-45       2     157 .]       3     150 ..       2     150 .. 0.89

  Alignments for each domain:
  == domain 1  score: 154.5 bits;  conditional E-value: 4.2e-49
         ARD   2 iyimddseegderlphhtspkekaeelelaklgvlrwkldaddeeeaeeeekilktkeeekkdidvevlkestpnfdeklekFfeEhlhedeeirlive 100
                 +y +d+   gd+r+ h++     ++e +l+ lgv++ + ++    ++++++ ++ +k++++ ++   + ++  + ++ek+++Ff+Ehlhedeeir+i++
  EEA18913.1   3 AYWYDNVS-GDQREDHDSR--RPVSESYLQSLGVVYHHFPEL--SSVNALAAERGYKNRDEITV---SPEKMGAVYEEKVKSFFSEHLHEDEEIRYILD 93 
                 67788887.7**9999998..78899999****999988888..56667777778888777776...35566899************************ PP

         ARD 101 GtgyFdvrskdeawirvlvekGDLivlPagiyhrFtltednkvkalRlFvekekwva 157
                 G+g+Fdvrs+d+aw+r++vek DL++lPagiyhrFt++ +n++ka+RlF++++kw++
  EEA18913.1  94 GDGFFDVRSQDDAWVRIRVEKDDLLILPAGIYHRFTTDAKNYIKAMRLFQDEPKWTP 150
                 *******************************************************86 PP

>> Cupin_2  Cupin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.7   0.0   1.8e-12   1.1e-08      12      60 ..      79     131 ..      70     139 .. 0.91

  Alignments for each domain:
  == domain 1  score: 34.7 bits;  conditional E-value: 1.8e-12
                 EEECSSSEEEEEEEEESEEEEEECTE.....EEEEETTEEEEE-TT-EEEEEE- CS
     Cupin_2  12 pshrHpgedeffyVleGegeltvdge.....eveleaGdsvyfpagtpHrfrNt 60 
                  +h H++e e++y+l+G g + v ++     ++++e++d+++ pag  Hrf  +
  EEA18913.1  79 SEHLHEDE-EIRYILDGDGFFDVRSQddawvRIRVEKDDLLILPAGIYHRFTTD 131
                 68******.***************88899*********************9765 PP

>> AraC_binding  AraC-like ligand binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0   3.1e-08   0.00019      15      66 ..      77     133 ..      70     149 .. 0.91

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 3.1e-08
                   SEEEETT-SEEEEEEEEE-EEEEETTEE.....EEE-TT-EEEE-TTS-EEEEE-TT CS
  AraC_binding  15 sfpphvhdeyvihyvteGtgrlrlngrt.....ydlgpGdlfLlppgepHdyesdse 66 
                    f++h h+  +i y+++G g + ++ +       +++++dl++lp g  H++  d+ 
    EEA18913.1  77 FFSEHLHEDEEIRYILDGDGFFDVRSQDdawvrIRVEKDDLLILPAGIYHRFTTDAK 133
                   58********************99999999999*******************99985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (173 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       396  (0.0220871); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.41u 0.28s 00:00:00.69 Elapsed: 00:00:00.44
# Mc/sec: 1171.89
//
Query:       EEA18914.1  [L=173]
Description: ARD/ARD family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.1e-45  154.7   0.2    2.5e-45  154.5   0.2    1.0  1  ARD           ARD/ARD' family
    6.5e-09   35.4   0.0    1.1e-08   34.7   0.0    1.3  1  Cupin_2       Cupin domain
    0.00012   22.0   0.0    0.00019   21.4   0.0    1.3  1  AraC_binding  AraC-like ligand binding domain


Domain annotation for each model (and alignments):
>> ARD  ARD/ARD' family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  154.5   0.2   4.2e-49   2.5e-45       2     157 .]       3     150 ..       2     150 .. 0.89

  Alignments for each domain:
  == domain 1  score: 154.5 bits;  conditional E-value: 4.2e-49
         ARD   2 iyimddseegderlphhtspkekaeelelaklgvlrwkldaddeeeaeeeekilktkeeekkdidvevlkestpnfdeklekFfeEhlhedeeirlive 100
                 +y +d+   gd+r+ h++     ++e +l+ lgv++ + ++    ++++++ ++ +k++++ ++   + ++  + ++ek+++Ff+Ehlhedeeir+i++
  EEA18914.1   3 AYWYDNVS-GDQREDHDSR--RPVSESYLQSLGVVYHHFPEL--SSVNALAAERGYKNRDEITV---SPEKMGAVYEEKVKSFFSEHLHEDEEIRYILD 93 
                 67788887.7**9999998..78899999****999988888..56667777778888777776...35566899************************ PP

         ARD 101 GtgyFdvrskdeawirvlvekGDLivlPagiyhrFtltednkvkalRlFvekekwva 157
                 G+g+Fdvrs+d+aw+r++vek DL++lPagiyhrFt++ +n++ka+RlF++++kw++
  EEA18914.1  94 GDGFFDVRSQDDAWVRIRVEKDDLLILPAGIYHRFTTDAKNYIKAMRLFQDEPKWTP 150
                 *******************************************************86 PP

>> Cupin_2  Cupin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.7   0.0   1.8e-12   1.1e-08      12      60 ..      79     131 ..      70     139 .. 0.91

  Alignments for each domain:
  == domain 1  score: 34.7 bits;  conditional E-value: 1.8e-12
                 EEECSSSEEEEEEEEESEEEEEECTE.....EEEEETTEEEEE-TT-EEEEEE- CS
     Cupin_2  12 pshrHpgedeffyVleGegeltvdge.....eveleaGdsvyfpagtpHrfrNt 60 
                  +h H++e e++y+l+G g + v ++     ++++e++d+++ pag  Hrf  +
  EEA18914.1  79 SEHLHEDE-EIRYILDGDGFFDVRSQddawvRIRVEKDDLLILPAGIYHRFTTD 131
                 68******.***************88899*********************9765 PP

>> AraC_binding  AraC-like ligand binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0   3.1e-08   0.00019      15      66 ..      77     133 ..      70     149 .. 0.91

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 3.1e-08
                   SEEEETT-SEEEEEEEEE-EEEEETTEE.....EEE-TT-EEEE-TTS-EEEEE-TT CS
  AraC_binding  15 sfpphvhdeyvihyvteGtgrlrlngrt.....ydlgpGdlfLlppgepHdyesdse 66 
                    f++h h+  +i y+++G g + ++ +       +++++dl++lp g  H++  d+ 
    EEA18914.1  77 FFSEHLHEDEEIRYILDGDGFFDVRSQDdawvrIRVEKDDLLILPAGIYHRFTTDAK 133
                   58********************99999999999*******************99985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (173 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       396  (0.0220871); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.41u 0.29s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1199.46
//
Query:       EEA18915.1  [L=684]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   9.2e-102  341.1   0.0   1.2e-101  340.7   0.0    1.1  1  Tyr-DNA_phospho  Tyrosyl-DNA phosphodiesterase
     0.0001   22.2   0.0     0.0029   17.5   0.0    2.3  2  PLDc_2           PLD-like domain
    0.00034   20.3   2.1    0.00034   20.3   2.1    3.1  3  UIM              Ubiquitin interaction motif
  ------ inclusion threshold ------
      0.076   12.8   0.1        1.9    8.3   0.1    2.6  2  RAP80_UIM        RAP80 N-terminal ubiquitin interaction motif
       0.36   10.5   3.6       0.66    9.7   3.6    1.4  1  QWRF             QWRF family


Domain annotation for each model (and alignments):
>> Tyr-DNA_phospho  Tyrosyl-DNA phosphodiesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  340.7   0.0  3.3e-105  1.2e-101       2     420 ..     221     670 ..     220     673 .. 0.87

  Alignments for each domain:
  == domain 1  score: 340.7 bits;  conditional E-value: 3.3e-105
                      EE--TTTT----------EE-HHHHH--TTEEEEEEE-S-EEHHHHHTTS.-T-...-EEEEEE..............ETTSEE-TEEEEEE-- CS
  Tyr-DNA_phospho   2 lkltkirdlpeesernkdtitlkdilgdplleeavqfnFlfdlefllsqldedvrrkvkvvivhgakkeedeererleekakrypnvelieakm 95 
                      +k+t++ +++    rn+d+i+++++l++ +le a++++F++d++++++++++   +k+++++v++ak+e++  r + +e+++++pn++l++++m
       EEA18915.1 221 VKKTWAFGYS----RNGDDIKIEEVLQTADLELALLSAFQWDMQWMFTKFRTP--NKTRFLMVMQAKEEST--RLQYQEETANMPNIRLCFPPM 306
                      6889999988....89**********************************884..58*******8666555..88888**************** PP

                      -.TT--B---EEEEEETTSEEEEEEESS-BSHHHHHSSB-E......EEE---EEE......S--SS--HHHHHHHHHHHTT..-HHHHTHHHH CS
  Tyr-DNA_phospho  96 pepfgthHsKmmilfyeddslrvvihtaNlieaDwgnmtqg......vwrspllpllesskeseeesgtrFkrdLleYLkaygkkklkkliekl 183
                      +++++++HsK+m+lf+++ +lr+v+++aN++++Dwg+  qg      v+  + lp+ +s+++++++ +t F ++L ++Lka + +  +++i+kl
       EEA18915.1 307 DGQVNCMHSKLMLLFHPE-YLRIVVPSANMVPYDWGE--QGgvmentVFLID-LPK-KSTNDAADSPKTAFYEELSYFLKASTLH--ENIIAKL 393
                      ******************.******************..3335666655555.333.3568899999***************999..******* PP

                      HTEE-GGGT.-EEEEE---TTS--.....HHHHHHHHHHHTCT..T----EEEEEEE-SBB---S-.SSS---HHHHTHHHHHTTSS....... CS
  Tyr-DNA_phospho 184 kkyDfsevr.valiaSvPgrhkgs.ktkwGlakLkkalkelplekeekskeleivaqvSSigslgstekwlknefleslspalqgkd....... 268
                      + +Df+e++ +a++++++g+h g+  t++G+++L+ka+++l+l   ++ ++++i++++SSigsl++       ef++s++ ++qgk+       
       EEA18915.1 394 SAFDFKETNrYAFVHTIGGSHFGEsLTRTGHCGLGKAVTSLGL---KTREPINIDFVTSSIGSLTD-------EFMRSIYLSAQGKQtlysiir 477
                      *******************************************...333479*************9.......9************9******* PP

                      .................---HHH..HHTEEEE..EE--BSGGGTTSTTGGGGGGG-B---...SGGHHHHHH..HTS--EEEE-TT..TTTTT- CS
  Tyr-DNA_phospho 269 .................kskeee..ekkskpkfkiifPtveevrrsldgyasggsihfkiqsaqqqkqleel..kpylckwkqdseeeagRkra 341
                                       ++   +  +++ k +f++++P++++v++s +  +s+g+i+f+ ++++ +k+++++  +++           ++R+++
       EEA18915.1 478 tiilnvscrlggdgstnAQ---RttSSEWKSRFRVYYPSEQTVSQSKGSRRSAGTICFQEKWFTGPKFPRNTlhDCI-----------SRREGL 557
                      ******9999998764311...123444556666***********************************88875555...........89**** PP

                      -B--EE.EEEE.....--STTSEESEEEEES--BSHHHH--S.........SS--SSBEEEEEEEGG........................... CS
  Tyr-DNA_phospho 342 apHiKt.yirf.....ssktlkkidWalltSaNLSkqAWGeleka...ke.elrirsyElGVlvlpk..............kdlpee....... 404
                      ++H+K+ ++r          +++  Wa+++SaNLS++AWG+++++   ke +l++r++E+GVlv+ +              k    +       
       EEA18915.1 558 LMHNKMmFVRPekpinLPGGSNCAGWAYVGSANLSESAWGKVVHDrvrKEpKLNCRNWECGVLVPITelppaagsdgeeqnK----Dsakkedk 647
                      ******9****9999855566789*******************88776447****************777777776666553....04455688 PP

                      .......------SEEESS-SSE CS
  Tyr-DNA_phospho 405 .......eektevgvrvPydlpl 420
                              e + ++v+vP+++p 
       EEA18915.1 648 sgaegdiVEIFGSTVPVPMRVPA 670
                      8999999999***********97 PP

>> PLDc_2  PLD-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0     0.045   1.6e+02      55     106 ..     283     340 ..     246     363 .. 0.68
   2 !   17.5   0.0     8e-07    0.0029      80     107 ..     557     597 ..     535     621 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.045
      PLDc_2  55 easlkelkellleagvevrvfet.ll...gslHaKlyli.dgk..tvivGSsNltkrgl 106
                 e ++ +++e  +++  ++r++ + ++   + +H+Kl+l  + +    +v S+N+ +  +
  EEA18915.1 283 ESTRLQYQEE-TANMPNIRLCFPpMDgqvNCMHSKLMLLfHPEylRIVVPSANMVPYDW 340
                 4444455555.45555566655332244599****998757664455678888766655 PP

  == domain 2  score: 17.5 bits;  conditional E-value: 8e-07
      PLDc_2  80 gslHaKlylidgk.............tvivGSsNltkrgld 107
                   +H+K++ ++ +             +++vGS+Nl+++++ 
  EEA18915.1 557 LLMHNKMMFVRPEkpinlpggsncagWAYVGSANLSESAWG 597
                 57*********77799999999*****************95 PP

>> UIM  Ubiquitin interaction motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.1      0.26   9.4e+02       4      17 .]       9      22 ..       8      22 .. 0.80
   2 !   20.3   2.1   9.5e-08   0.00034       3      16 ..      59      72 ..      59      72 .. 0.98
   3 ?   -1.2   0.2      0.71   2.5e+03       2       9 ..     130     137 ..     130     137 .. 0.90

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.26
         UIM  4 edLqrAlalSlqEa 17
                  L+ Ala S+ ++
  EEA18915.1  9 PALRTALAESMRDQ 22
                66888******875 PP

  == domain 2  score: 20.3 bits;  conditional E-value: 9.5e-08
         UIM  3 dedLqrAlalSlqE 16
                dedL+rA+alS+qE
  EEA18915.1 59 DEDLRRAIALSMQE 72
                9************9 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 0.71
         UIM   2 EdedLqrA 9  
                 E+e L+r+
  EEA18915.1 130 EEERLARV 137
                 9*****95 PP

>> RAP80_UIM  RAP80 N-terminal ubiquitin interaction motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.0     0.086   3.1e+02      31      48 ..       3      20 ..       2      27 .. 0.80
   2 ?    8.3   0.1   0.00053       1.9      24      55 ..      47      78 ..      44      80 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.086
   RAP80_UIM 31 qeEeEEeLLRkAiAEsLn 48
                qe+  +  LR A+AEs+ 
  EEA18915.1  3 QEDYHDPALRTALAESMR 20
                77777888********86 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.00053
   RAP80_UIM 24 EArqvndqeEeEEeLLRkAiAEsLnsCqsses 55
                EA+ ++  +Ee +e LR+AiA s++  q s  
  EEA18915.1 47 EANIIDLEDEEGDEDLRRAIALSMQEIQNSSP 78
                667777778999999*********99998875 PP

>> QWRF  QWRF family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   3.6   0.00018      0.66      17     105 ..     140     226 ..     116     248 .. 0.65

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00018
        QWRF  17 arflqe.tssrlrrlsdpgsptsssskvkskkssldsaplssprsranslar..g.gsaralsPsklssstsspsrglespsrprsssslkvs 105
                 +++ ++ +   lrr+ + ++++ s+  v+ +k++l + p++++++    lar  + +++ra+ P++ ss+t +++++ +sp+ p+  ++ + +
  EEA18915.1 140 RKAESSiSPPPLRRDAKVARRDVSP--VQDSKFELTKSPSTTAAQA---LARpkKpTASRASTPESKSSKT-AQPSSTPSPQFPKGVVKKTWA 226
                 3333334555667777777777777..7777777766566666665...3332133489*****9988855.555556799999888776554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (684 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       517  (0.028836); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.63u 0.31s 00:00:00.94 Elapsed: 00:00:00.47
# Mc/sec: 4347.22
//
Query:       EEA18916.1  [L=596]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.8e-88  296.7   0.0    3.4e-88  296.4   0.0    1.1  1  Tyr-DNA_phospho  Tyrosyl-DNA phosphodiesterase
    0.00029   20.5   2.1    0.00029   20.5   2.1    3.2  3  UIM              Ubiquitin interaction motif
    0.00031   20.6   0.0       0.01   15.7   0.0    2.3  2  PLDc_2           PLD-like domain
  ------ inclusion threshold ------
       0.31   10.7   3.7       0.57    9.9   3.7    1.4  1  QWRF             QWRF family
       0.46   10.3   3.1        1.6    8.5   0.1    2.6  3  RAP80_UIM        RAP80 N-terminal ubiquitin interaction motif


Domain annotation for each model (and alignments):
>> Tyr-DNA_phospho  Tyrosyl-DNA phosphodiesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  296.4   0.0   9.5e-92   3.4e-88       2     374 ..     221     596 .]     220     596 .] 0.89

  Alignments for each domain:
  == domain 1  score: 296.4 bits;  conditional E-value: 9.5e-92
                      EE--TTTT----------EE-HHHHH--TTEEEEEEE-S-EEHHHHHTTS.-T-...-EEEEEE..............ETTSEE-TEEEEEE-- CS
  Tyr-DNA_phospho   2 lkltkirdlpeesernkdtitlkdilgdplleeavqfnFlfdlefllsqldedvrrkvkvvivhgakkeedeererleekakrypnvelieakm 95 
                      +k+t++ +++    rn+d+i+++++l++ +le a++++F++d++++++++++   +k+++++v++ak+e++  r + +e+++++pn++l++++m
       EEA18916.1 221 VKKTWAFGYS----RNGDDIKIEEVLQTADLELALLSAFQWDMQWMFTKFRTP--NKTRFLMVMQAKEEST--RLQYQEETANMPNIRLCFPPM 306
                      6889999988....89**********************************884..58*******8666555..88888**************** PP

                      -.TT--B---EEEEEETTSEEEEEEESS-BSHHHHHSSB-E......EEE---EEE......S--SS--HHHHHHHHHHHTT..-HHHHTHHHH CS
  Tyr-DNA_phospho  96 pepfgthHsKmmilfyeddslrvvihtaNlieaDwgnmtqg......vwrspllpllesskeseeesgtrFkrdLleYLkaygkkklkkliekl 183
                      +++++++HsK+m+lf+++ +lr+v+++aN++++Dwg+  qg      v+  + lp+ +s+++++++ +t F ++L ++Lka + +  +++i+kl
       EEA18916.1 307 DGQVNCMHSKLMLLFHPE-YLRIVVPSANMVPYDWGE--QGgvmentVFLID-LPK-KSTNDAADSPKTAFYEELSYFLKASTLH--ENIIAKL 393
                      ******************.******************..3335666655555.333.3568899999***************999..******* PP

                      HTEE-GGGT.-EEEEE---TTS--.....HHHHHHHHHHHTCT..T----EEEEEEE-SBB---S-.SSS---HHHHTHHHHHTTSS....... CS
  Tyr-DNA_phospho 184 kkyDfsevr.valiaSvPgrhkgs.ktkwGlakLkkalkelplekeekskeleivaqvSSigslgstekwlknefleslspalqgkd....... 268
                      + +Df+e++ +a++++++g+h g+  t++G+++L+ka+++l+l   ++ ++++i++++SSigsl++       ef++s++ ++qgk+       
       EEA18916.1 394 SAFDFKETNrYAFVHTIGGSHFGEsLTRTGHCGLGKAVTSLGL---KTREPINIDFVTSSIGSLTD-------EFMRSIYLSAQGKQtlysiir 477
                      *******************************************...333479*************9.......9************9******* PP

                      .................---HHH..HHTEEEE..EE--BSGGGTTSTTGGGGGGG-B---...SGGHHHHHH..HTS--EEEE-TT..TTTTT- CS
  Tyr-DNA_phospho 269 .................kskeee..ekkskpkfkiifPtveevrrsldgyasggsihfkiqsaqqqkqleel..kpylckwkqdseeeagRkra 341
                                       ++   +  +++ k +f++++P++++v++s +  +s+g+i+f+ ++++ +k+++++  +++           ++R+++
       EEA18916.1 478 tiilnvscrlggdgstnAQ---RttSSEWKSRFRVYYPSEQTVSQSKGSRRSAGTICFQEKWFTGPKFPRNTlhDCI-----------SRREGL 557
                      ******9999998764311...123444556666***********************************88875555...........89**** PP

                      -B--EE.EEEE.....--STTSEESEEEEES--BSHHHH CS
  Tyr-DNA_phospho 342 apHiKt.yirf.....ssktlkkidWalltSaNLSkqAW 374
                      ++H+K+ ++r          +++  Wa+++SaNLS++AW
       EEA18916.1 558 LMHNKMmFVRPekpinLPGGSNCAGWAYVGSANLSESAW 596
                      ******9****9999855566789*************** PP

>> UIM  Ubiquitin interaction motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.1      0.23   8.1e+02       4      17 .]       9      22 ..       8      22 .. 0.80
   2 !   20.5   2.1   8.1e-08   0.00029       3      16 ..      59      72 ..      59      72 .. 0.98
   3 ?   -1.0   0.2      0.61   2.2e+03       2       9 ..     130     137 ..     130     137 .. 0.90

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.23
         UIM  4 edLqrAlalSlqEa 17
                  L+ Ala S+ ++
  EEA18916.1  9 PALRTALAESMRDQ 22
                66888******875 PP

  == domain 2  score: 20.5 bits;  conditional E-value: 8.1e-08
         UIM  3 dedLqrAlalSlqE 16
                dedL+rA+alS+qE
  EEA18916.1 59 DEDLRRAIALSMQE 72
                9************9 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 0.61
         UIM   2 EdedLqrA 9  
                 E+e L+r+
  EEA18916.1 130 EEERLARV 137
                 9*****95 PP

>> PLDc_2  PLD-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0     0.036   1.3e+02      55     106 ..     283     340 ..     244     364 .. 0.69
   2 !   15.7   0.0   2.8e-06      0.01      80     106 ..     557     596 .]     535     596 .] 0.87

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.036
      PLDc_2  55 easlkelkellleagvevrvfet.ll...gslHaKlyli.dgk..tvivGSsNltkrgl 106
                 e ++ +++e  +++  ++r++ + ++   + +H+Kl+l  + +    +v S+N+ +  +
  EEA18916.1 283 ESTRLQYQEE-TANMPNIRLCFPpMDgqvNCMHSKLMLLfHPEylRIVVPSANMVPYDW 340
                 4444555555.55555566655332244599****998757664455678888766665 PP

  == domain 2  score: 15.7 bits;  conditional E-value: 2.8e-06
      PLDc_2  80 gslHaKlylidgk.............tvivGSsNltkrgl 106
                   +H+K++ ++ +             +++vGS+Nl+++++
  EEA18916.1 557 LLMHNKMMFVRPEkpinlpggsncagWAYVGSANLSESAW 596
                 57*********77799999999**************9997 PP

>> QWRF  QWRF family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   3.7   0.00016      0.57      17     105 ..     140     226 ..     114     248 .. 0.65

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00016
        QWRF  17 arflqe.tssrlrrlsdpgsptsssskvkskkssldsaplssprsranslar..g.gsaralsPsklssstsspsrglespsrprsssslkvs 105
                 +++ ++ +   lrr+ + ++++ s+  v+ +k++l + p++++++    lar  + +++ra+ P++ ss+t +++++ +sp+ p+  ++ + +
  EEA18916.1 140 RKAESSiSPPPLRRDAKVARRDVSP--VQDSKFELTKSPSTTAAQA---LARpkKpTASRASTPESKSSKT-AQPSSTPSPQFPKGVVKKTWA 226
                 3333334555667777777777777..7777777766566666665...3332133489*****9988855.555556799999888776554 PP

>> RAP80_UIM  RAP80 N-terminal ubiquitin interaction motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.0     0.073   2.6e+02      31      48 ..       3      20 ..       2      27 .. 0.80
   2 ?    8.5   0.1   0.00045       1.6      24      55 ..      47      78 ..      44      80 .. 0.83
   3 ?   -4.4   0.4         5   1.8e+04      34      42 ..     130     138 ..     127     145 .. 0.60

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.073
   RAP80_UIM 31 qeEeEEeLLRkAiAEsLn 48
                qe+  +  LR A+AEs+ 
  EEA18916.1  3 QEDYHDPALRTALAESMR 20
                77777888********86 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00045
   RAP80_UIM 24 EArqvndqeEeEEeLLRkAiAEsLnsCqsses 55
                EA+ ++  +Ee +e LR+AiA s++  q s  
  EEA18916.1 47 EANIIDLEDEEGDEDLRRAIALSMQEIQNSSP 78
                667777778999999*********99998875 PP

  == domain 3  score: -4.4 bits;  conditional E-value: 5
   RAP80_UIM  34 eEEeLLRkA 42 
                 eEE L R A
  EEA18916.1 130 EEERLARVA 138
                 566676644 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (596 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       654  (0.0364772); expected 358.6 (0.02)
Passed bias filter:                      405  (0.0225891); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 3919.83
//
Query:       EEA18917.1  [L=339]
Description: phosphatidyl synthase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.7e-14   54.3   0.7    1.7e-14   54.3   0.7    2.2  2  CDP-OH_P_transf  CDP-alcohol phosphatidyltransferase


Domain annotation for each model (and alignments):
>> CDP-OH_P_transf  CDP-alcohol phosphatidyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.3   0.7   9.5e-19   1.7e-14       2      66 .]     126     189 ..     125     189 .. 0.91
   2 ?   -1.5   1.4      0.25   4.4e+03      27      35 ..     208     222 ..     191     297 .. 0.50

  Alignments for each domain:
  == domain 1  score: 54.3 bits;  conditional E-value: 9.5e-19
                      -HHHHHHHHHHHHHHHHHGGGS-H..HHHHHHHHHHHHHTTHHHHHHHHTT---HHHHHHHHHHH CS
  CDP-OH_P_transf   2 lPnaiTllrlllsvlailllltyyplvlailllliasltDalDGklARrlnqvstlGkllDslaD 66 
                      +Pn++T++rll++ +  +l l+ ++ ++a+ l+ +a++tD++DG++ARr+n ++  G ++D+ aD
       EEA18917.1 126 VPNILTFSRLLAAPAVGYL-LVHNHHTAALSLFAYAGITDLVDGYIARRYNLQTVVGTIIDPAAD 189
                      7**********98888865.577888**************************888*********9 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.25
                      .HHHHHHH......H CS
  CDP-OH_P_transf  27 lvlailll......l 35 
                      ++la+l+l       
       EEA18917.1 208 VWLAVLILgrdvglS 222
                      344444443333320 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (339 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       614  (0.0342462); expected 358.6 (0.02)
Passed bias filter:                      442  (0.0246528); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2416.21
//
Query:       EEA18918.1  [L=1534]
Description: ABC drug exporter AtrF [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.8e-81  271.5  55.0    4.4e-42  143.9  17.9    3.4  3  ABC2_membrane  ABC-2 type transporter
      4e-36  124.5   0.1    2.9e-18   66.7   0.0    2.5  2  ABC_tran       ABC transporter
    2.1e-28   98.0   3.1    2.3e-24   85.1   0.0    2.9  2  PDR_CDR        CDR ABC transporter
      9e-15   55.1   0.4    2.4e-14   53.7   0.4    1.8  1  ABC_trans_N    ABC-transporter N-terminal
    1.6e-05   24.9   0.1     0.0011   18.9   0.1    2.3  2  RsgA_GTPase    RsgA GTPase
    2.9e-05   24.6   0.0    0.00054   20.5   0.0    2.5  2  AAA_18         AAA domain
    3.7e-05   24.2   0.1     0.0087   16.5   0.1    2.6  2  AAA_16         AAA ATPase domain
    7.9e-05   22.3   0.1     0.0036   16.9   0.0    2.4  2  cobW           CobW/HypB/UreG, nucleotide-binding domain
    9.2e-05   22.4   0.1      0.042   13.6   0.1    2.4  2  AAA_21         AAA domain, putative AbiEii toxin, Type IV TA 
    0.00012   22.2   0.0     0.0035   17.5   0.0    2.5  2  AAA_33         AAA domain
     0.0002   21.4   0.1      0.099   12.7   0.0    2.6  2  MMR_HSR1       50S ribosome-binding GTPase
    0.00028   21.2   0.2      0.067   13.5   0.0    3.5  3  AAA_22         AAA domain
      0.001   18.8   0.0       0.16   11.7   0.0    3.0  3  AAA_24         AAA domain
     0.0013   19.0   0.2     0.0036   17.6   0.1    1.8  1  AAA_28         AAA domain
     0.0027   17.4   0.7       0.53   10.1   0.2    2.6  2  AAA_29         P-loop containing region of AAA domain
     0.0042   17.0   0.2       0.26   11.2   0.2    2.5  2  NACHT          NACHT domain
     0.0077   15.8   1.5       0.47   10.0   0.2    3.2  3  AAA_25         AAA domain
  ------ inclusion threshold ------
      0.019   15.4   0.1         12    6.4   0.1    3.5  3  AAA            ATPase family associated with various cellular
       0.02   14.3   0.5       0.16   11.4   0.1    2.5  3  SMC_N          RecF/RecN/SMC N terminal domain
      0.039   14.4   1.8       0.87   10.0   0.1    2.9  2  AAA_17         AAA domain
      0.041   13.2   0.1       0.54    9.5   0.1    2.2  2  Septin         Septin
      0.061   13.3   0.4       0.66   10.0   0.3    2.3  2  TsaE           Threonylcarbamoyl adenosine biosynthesis prote
       0.11   11.6   1.7          4    6.5   0.2    3.0  4  NB-ARC         NB-ARC domain
       0.15   11.7   2.3        3.5    7.3   0.5    2.6  3  AAA_30         AAA domain
       0.17   11.2   0.7        6.9    5.9   0.2    2.4  2  FtsK_SpoIIIE   FtsK/SpoIIIE family
       0.25   10.6   0.8        1.2    8.3   0.5    2.1  2  Zeta_toxin     Zeta toxin


Domain annotation for each model (and alignments):
>> ABC2_membrane  ABC-2 type transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  143.9  17.9   6.4e-45   4.4e-42       2     210 .]     528     740 ..     527     740 .. 0.97
   2 ?   -1.5   0.4         2   1.4e+03      51      77 ..     798     824 ..     775     833 .. 0.69
   3 !  143.3  29.1   9.3e-45   6.4e-42       1     208 [.    1195    1405 ..    1195    1407 .. 0.97

  Alignments for each domain:
  == domain 1  score: 143.9 bits;  conditional E-value: 6.4e-45
  ABC2_membrane   2 qikallkreflqrwrdpslgllwrliqplllalvfgtvfgnlg.nsedglnrpgllffsvlflafsaltsvapvferergvlerelvsplyslsay 96 
                    q+ a++kre+ + ++d++++ +++++  +  al++ ++f++   n++++++r g+lffsvlfl+ + +t++ +  +++r +++r++++ +y++sa+
     EEA18918.1 528 QVAACVKREVWLLLGDKTSL-YTKFFIAIANALIVSSLFYGESlNTSGAFARGGILFFSVLFLGWLQMTEL-MPAVSGRTMIQRHRDYAFYRPSAV 621
                    899**************888.9******************8879999999*********************.77899******************* PP

  ABC2_membrane  97 vlakvlvelpvsllqalifllivyflvgldls..rfflflllllltalaasslgllisalapsfedasqlaslvllpllllsGffipidsm...pk 187
                     +a+v+v++p+ + +++if +i+yfl gld++  +ff++ll+++ t+++++s+ ++++al+p+++da+ ++++ l +l+++ G+ ip++++     
     EEA18918.1 622 SIARVVVDFPFLATLVTIFGIITYFLSGLDVDagKFFIYLLFVYTTTICITSMYRMFAALSPTIDDAVRFGGIALNLLVIFFGYAIPKSALlngSI 717
                    ********************************************************************************************7447 PP

  ABC2_membrane 188 wlqwiaylnPltyavealrsnlf 210
                    w+ w+ y+nP++ya+ea+++n+f
     EEA18918.1 718 WFGWLFYVNPVSYAYEAVLANEF 740
                    *********************97 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 2
  ABC2_membrane  51 nrpgllffsvlflafsaltsvapvfer 77 
                    n+  l++f+vl++ ++ +++ +++f +
     EEA18918.1 798 NFGVLVAFTVLYILVTVVANEMMTFAS 824
                    447788888888888888888777765 PP

  == domain 3  score: 143.3 bits;  conditional E-value: 9.3e-45
  ABC2_membrane    1 tqikallkreflqrwrdpslgllwrliqplllalvfgtvfgnlgnsedglnrpgllffsvlflafsaltsvapvferergvl.erelvsplysl 93  
                     tqi +l+kr flq+wrdps++ + +++  ++l+++ g+ f++lgn+ + l+  ++  f+++ +  + + s+ p f + r+++  re++s++y +
     EEA18918.1 1195 TQIEMLTKRVFLQYWRDPSYY-YGKIFVSVILGIFNGFTFWKLGNTVSSLQDRMFSTFLIILIPPIVMNSILPKFYMNRSLWeFREYPSRIYGW 1287
                     6999*****************.****************************9*******************************99********** PP

  ABC2_membrane   94 sayvlakvlvelpvsllqalifllivyflvgldls..rfflflllllltalaasslgllisalapsfedasqlaslvllpllllsGffipidsm 185 
                      a+++a+v++e+p+++l ++i+++++yf+vgl+ +  + ++++l+++l++++  s+g +i+a+apsf ++s++ ++++++++l+ G++ ++   
     EEA18918.1 1288 VAFCTANVVCEIPIAILTSVIYFVLWYFPVGLPTDssSAGYVFLMTMLFFFFQASWGQWICAFAPSFTVISNVLPFFFVMCNLFNGVVRSYAEY 1381
                     ***********************************9767******************************************************* PP

  ABC2_membrane  186 p.kwlqwiaylnPltyavealrsn 208 
                     p  w +wi+y+nP+t+ +++ +s+
     EEA18918.1 1382 PvFWKYWIYYANPITWWIRGTLSA 1405
                     9567779***********998876 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.7   0.0   4.2e-21   2.9e-18       4     136 ..     210     360 ..     207     361 .. 0.89
   2 !   55.5   0.0   1.3e-17   8.6e-15       1     137 []     900    1047 ..     900    1047 .. 0.91

  Alignments for each domain:
  == domain 1  score: 66.7 bits;  conditional E-value: 4.2e-21
                 EEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--...SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.........HHHTC...... CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.........xxxxx...... RF
    ABC_tran   4 vslklkegekvaivGenGaGKStLlkllagllkp...teGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren.........esdee...... 84 
                  +  ++ ge++ ++G+ GaG+St+lk++a+  +      G++ + g + +e +++++r e+ + p+++q+f +ltv ++         +   +      
  EEA18918.1 210 FTGVVRDGEMMLVLGRPGAGCSTFLKTIANDRSSyaaVLGDVSYGGISAEE-QHKHFRGEVNYNPEDDQHFATLTVWQTlkfslmnktK---Kgdrssv 304
                 5666899**********************9887755577999999988888.9******************************997763...2334678 PP

                 ...HHHHHHHSTTGGTTCBGESTTS.GGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 ...xxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  85 ...iekalsklglkelkdtvvkssp.ssLSgGqkqrvalarallkkpkllllDEpt 136
                    ++++l+ +g++++k+t v+++  + +SgG+++rv++a++l++k+++ ++D+ t
  EEA18918.1 305 piiLDALLKMFGISHTKNTQVGNEYvRGVSGGERKRVSIAETLASKSTVTCWDNST 360
                 8999*****************99989***************************987 PP

  == domain 2  score: 55.5 bits;  conditional E-value: 1.3e-17
                  EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--..SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH................ CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................ RF
    ABC_tran    1 lknvslklkegekvaivGenGaGKStLlkllagllkp..teGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren................ 79  
                  l+ vs   k+g ++a++G +GaGK+tLl++la+  k     G++l+dg++l       +++  g+++q + ++ + t+re                 
  EEA18918.1  900 LNGVSGYAKPGVMIALMGASGAGKTTLLNTLAQRQKMgvVTGDMLVDGRPLGA----DFQRGTGFCEQMDLHDGTATIREAlefsailrqdratprs 992 
                  68899999**************************9988899**********99....9***********9999999**********99888777554 PP

                  HHHTCHHHHHHHSTTGGTTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEE.EESTTT CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxx RF
    ABC_tran   80 esdeeiekalsklglkelkdtvvksspssLSgGqkqrvalarallkkpklll.lDEpta 137 
                  e+ + ++++++ l+l++++d  +    ssL   qk+rv +   l+ kp+lll lDEpt+
  EEA18918.1  993 EKIDYVNRIIDLLELEDIQDALI----SSLGVEQKKRVTIGVELAAKPSLLLfLDEPTS 1047
                  444449***********999999....*********************987549***96 PP

>> PDR_CDR  CDR ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.1   0.0   3.4e-27   2.3e-24       1      91 [.     753     840 ..     753     841 .. 0.97
   2 !   11.3   1.4   0.00035      0.24      29      68 ..    1463    1501 ..    1452    1510 .. 0.84

  Alignments for each domain:
  == domain 1  score: 85.1 bits;  conditional E-value: 3.4e-27
     PDR_CDR   1 vPsgpgyenvseenrvCavvGavpGqeyVsGddYlelsfgyssshlwrnfgiliaflifflalyllatelisaekskgevlvfkrgkapkk 91 
                 vPsgpg       +++Ca+ G+   q+ VsG +Yle+sfg++++hlwrnfg+l+af++++++++++a e++++++++g +lvfk+++++k+
  EEA18918.1 753 VPSGPGAV---AGHQSCALPGSSVDQTRVSGAAYLETSFGFTRHHLWRNFGVLVAFTVLYILVTVVANEMMTFASGGGGALVFKKSRRSKQ 840
                 89***988...79************************************************************************998875 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00035
     PDR_CDR   29 VsGddYlelsfgyssshlwrnfgiliaflifflalyllat 68  
                   +G++Y++ +++ + +++w  fgi +af+i+  +l  +++
  EEA18918.1 1463 SNGSEYMH-TLNVQDDDKWHCFGIFLAFVIINWVLVYFFI 1501
                  589****9.9*******************99777665554 PP

>> ABC_trans_N  ABC-transporter N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.7   0.4   3.5e-17   2.4e-14       2      81 .]      73     175 ..      72     175 .. 0.71

  Alignments for each domain:
  == domain 1  score: 53.7 bits;  conditional E-value: 3.5e-17
  ABC_trans_N   2 Lartlsrqssssssssss...................e.....sssedeeeedse.Fdlekwlknlreridr.dgikprklGVvFknLtVeGvgsgad 73 
                  ++r+lsr+s ++++s+ s                   +     ++se+ +   ++ Fdl ++l  +  +++  +g++ +k+GV +knLtV Gv ++a+
   EEA18918.1  73 MRRELSRLSLQRTRSQVSrrsvrpasrwrsatktttkDiekgdDESEQHD---QDdFDLGEFLMGGTLERRTtAGEPAKKVGVLYKNLTVMGVQASAS 167
                  67788877444444444446777777799887765441533233333333...566****999988777776499*********************** PP

  ABC_trans_N  74 yqpTvgna 81 
                  +++T+++a
   EEA18918.1 168 FVKTLPEA 175
                  *****975 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0     0.093        64      94     123 ..     211     241 ..     201     262 .. 0.78
   2 !   18.9   0.1   1.7e-06    0.0011     100     126 ..     911     937 ..     868     944 .. 0.80

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.093
                  HHHCTT.SEEEEECSTTSSHHHHHHHHCTT- CS
  RsgA_GTPase  94 kellkd.ktsvlvGqSGvGKStLinallpel 123
                  + +++d ++++++G  G+G St++++++++ 
   EEA18918.1 211 TGVVRDgEMMLVLGRPGAGCSTFLKTIANDR 241
                  55666669999***************99863 PP

  == domain 2  score: 18.9 bits;  conditional E-value: 1.7e-06
                  SEEEEECSTTSSHHHHHHHHCTT---- CS
  RsgA_GTPase 100 ktsvlvGqSGvGKStLinallpelelk 126
                   +++l+G SG+GK+tL+n+l++++++ 
   EEA18918.1 911 VMIALMGASGAGKTTLLNTLAQRQKMG 937
                  5789*****************987664 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0      0.68   4.7e+02       2      44 ..     221     264 ..     220     316 .. 0.69
   2 !   20.5   0.0   7.8e-07   0.00054       1      70 [.     913     989 ..     913    1040 .. 0.78

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.68
      AAA_18   2 lltGtpGvGKttlakeLskrl.gfgvnlrdvakenglllevdpe 44 
                 l+ G pG+G +t+ k +++    +  +l+dv + + + +e+ ++
  EEA18918.1 221 LVLGRPGAGCSTFLKTIANDRsSYAAVLGDVSYGGISAEEQHKH 264
                 689**************888745566666666665555555555 PP

  == domain 2  score: 20.5 bits;  conditional E-value: 7.8e-07
      AAA_18   1 IlltGtpGvGKttlakeLskrlgfgvnlrdvakenglllevdpealdeskrldedkldklldaleenss.......a 70 
                 I+l+G++G+GKttl + L++r ++gv+ +d++ ++++l  +++  +  ++++d +   + +++  e s+       +
  EEA18918.1 913 IALMGASGAGKTTLLNTLAQRQKMGVVTGDMLVDGRPLGADFQRGTGFCEQMDLHDGTATIREALEFSAilrqdraT 989
                 89******************9999*******************9888888888887777777776666655555542 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.0     0.045        31      18      52 ..     213     254 ..     198     341 .. 0.69
   2 !   16.5   0.1   1.3e-05    0.0087      25      95 ..     911     974 ..     897    1075 .. 0.52

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.045
      AAA_16  18 rvrsgrpelvllsGesGvGKsslvrellralekd..........g 52 
                  vr+g  e++l+ G +G G s+ ++++++  + +          g
  EEA18918.1 213 VVRDG--EMMLVLGRPGAGCSTFLKTIANDRS-SyaavlgdvsyG 254
                 45555..89****************9997222.123455555543 PP

  == domain 2  score: 16.5 bits;  conditional E-value: 1.3e-05
      AAA_16  25 elvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipysa.laqalareellrqlldeaesaele 95 
                  ++ l G+sG GK++l+++l++   ++++ +++g+      ++p+ a + +     ++++q++ ++ +a  +
  EEA18918.1 911 VMIALMGASGAGKTTLLNTLAQ---RQKMGVVTGDMLVD--GRPLGAdFQRGT---GFCEQMDLHDGTATIR 974
                 6899*****************6...44456666666555..455544333333...4444444443332222 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.0      0.11        76       3      37 ..     220     252 ..     218     264 .. 0.78
   2 !   16.9   0.0   5.2e-06    0.0036       3      43 ..     913     947 ..     911     986 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.11
                 EEEEESTTCCHHHHHHHHHCT--SS-EEEEESS-S CS
        cobW   3 tvltGflGsGKTtLlnhllenraglklavivNefg 37 
                 +++ G +G+G +t+l+++ ++    ++a ++++++
  EEA18918.1 220 MLVLGRPGAGCSTFLKTIAND--RSSYAAVLGDVS 252
                 67889************9976..456677777776 PP

  == domain 2  score: 16.9 bits;  conditional E-value: 5.2e-06
                 EEEEESTTCCHHHHHHHHHCT--SS-EEEEESS-SSCHCCC CS
        cobW   3 tvltGflGsGKTtLlnhllenraglklavivNefgevsiDa 43 
                 + l G  G+GKTtLln+l ++   +k+ v+++++    +D+
  EEA18918.1 913 IALMGASGAGKTTLLNTLAQR---QKMGVVTGDML---VDG 947
                 67899*************987...89*******97...555 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   0.0      0.01       7.2       3      21 ..     914     932 ..     912     966 .. 0.75
   2 !   13.6   0.1   6.1e-05     0.042     257     296 ..    1036    1074 ..     979    1081 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.01
      AAA_21   3 vliGpNgsGKSnLLdaldl 21 
                 +l G+ g+GK++LL +l  
  EEA18918.1 914 ALMGASGAGKTTLLNTLAQ 932
                 789************9954 PP

  == domain 2  score: 13.6 bits;  conditional E-value: 6.1e-05
      AAA_21  257 kgsllliDEpEngLHPkllrrllellkelsrngaQviltT 296 
                  ++ ll++DEp +gL+ ++  +++++l++l+   +Q i+ T
  EEA18918.1 1036 PSLLLFLDEPTSGLDSQAAFSIVRFLRKLAH-AGQAIVCT 1074
                  3389**********************66655.59997776 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.0      0.32   2.2e+02       2      39 ..     220     258 ..     219     314 .. 0.64
   2 !   17.5   0.0   5.1e-06    0.0035       2      50 ..     913     962 ..     912    1006 .. 0.72

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.32
      AAA_33   2 vllvGlpGsGKstlaerllkklg.avllssdtlrrrlfg 39 
                 +l+ G pG+G st+++ +++ +  +  +  d+ +  + +
  EEA18918.1 220 MLVLGRPGAGCSTFLKTIANDRSsYAAVLGDVSYGGISA 258
                 6889*************9988878776666764444443 PP

  == domain 2  score: 17.5 bits;  conditional E-value: 5.1e-06
      AAA_33   2 vllvGlpGsGKstlaerllkklgavllssdtlrr.rlfgtdqqsktdytr 50 
                 + l G++G+GK+tl+  l++++++ +++ d l + r  g d q+ t   +
  EEA18918.1 913 IALMGASGAGKTTLLNTLAQRQKMGVVTGDMLVDgRPLGADFQRGTGFCE 962
                 7799**************************98886666677776664333 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.0     0.018        12       3      27 ..     221     245 ..     219     252 .. 0.84
   2 !   12.7   0.0   0.00014     0.099       2      22 ..     913     933 ..     912     946 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.018
                 EEEESTTSSHHHHHHHHHTSTEEES CS
    MMR_HSR1   3 aivGrpNvGKStLinaltgekaivs 27 
                 +++Grp +G St+++++ ++++  +
  EEA18918.1 221 LVLGRPGAGCSTFLKTIANDRSSYA 245
                 799***************9977554 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 0.00014
                 EEEEESTTSSHHHHHHHHHTS CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltge 22 
                 +a++G + +GK+tL+n+l ++
  EEA18918.1 913 IALMGASGAGKTTLLNTLAQR 933
                 89****************987 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.0      0.15     1e+02       4      31 ..     216     243 ..     214     306 .. 0.84
   2 ?   -2.1   0.0       6.1   4.2e+03      83     103 ..     394     413 ..     354     428 .. 0.72
   3 !   13.5   0.0   9.8e-05     0.067       7      29 ..     912     934 ..     907     965 .. 0.88

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.15
      AAA_22   4 tagilvvtGesGtGKTtllrrlleqlde 31 
                 +  +++v G +G+G +t l+++++    
  EEA18918.1 216 DGEMMLVLGRPGAGCSTFLKTIANDRSS 243
                 56799****************9997654 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 6.1
      AAA_22  83 eqalraravielliiDEaqhl 103
                  + + + ++ ++l+iDE   l
  EEA18918.1 394 GEGIYELMD-KVLVIDEGRML 413
                 444555666.9*****96655 PP

  == domain 3  score: 13.5 bits;  conditional E-value: 9.8e-05
      AAA_22   7 ilvvtGesGtGKTtllrrlleql 29 
                 +++++G sG+GKTtll++l+++ 
  EEA18918.1 912 MIALMGASGAGKTTLLNTLAQRQ 934
                 799****************9987 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.0      0.13        93       4      69 ..     219     282 ..     216     287 .. 0.70
   2 !   11.7   0.0   0.00023      0.16       3      23 ..     911     933 ..     910    1008 .. 0.80
   3 ?   -0.5   0.0       1.2   8.5e+02     109     131 ..    1055    1077 ..    1050    1084 .. 0.88

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.13
      AAA_24   4 kiliyGpsgiGKTtlakel...gpkplfidtekGlksldadkfpdieswedfldevvelaaeladyktl 69 
                 ++l+ G +g+G +t++k++     + + +  + ++  + a +     + + f+ ev++++++++++ tl
  EEA18918.1 219 MMLVLGRPGAGCSTFLKTIandRSSYAAVLGDVSYGGISAEE-----QHKHFRGEVNYNPEDDQHFATL 282
                 799***************977655555555555555555555.....3366777777777777777766 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 0.00023
      AAA_24   3 lkiliyGpsgiGKTtlakel..g 23 
                 ++i+++G sg+GKTtl+++l   
  EEA18918.1 911 VMIALMGASGAGKTTLLNTLaqR 933
                 689****************9651 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 1.2
      AAA_24  109 eefrrllkklqelrknvifiahe 131 
                    ++r+l+kl ++++ ++++ h+
  EEA18918.1 1055 FSIVRFLRKLAHAGQAIVCTIHQ 1077
                  56899***************997 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.1   5.2e-06    0.0036       2      27 ..     913     939 ..     912     945 .. 0.85

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 5.2e-06
      AAA_28   2 ivitGgestGKTtlleaLaar.gypvv 27 
                 i+++G++++GKTtll+ La+r ++ vv
  EEA18918.1 913 IALMGASGAGKTTLLNTLAQRqKMGVV 939
                 89*****************98645444 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.0     0.033        23      22      39 ..     216     234 ..     208     239 .. 0.83
   2 !   10.1   0.2   0.00077      0.53      23      40 ..     910     928 ..     902     932 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.033
      AAA_29  22 kg.atlltGpsGsGKSTll 39 
                 +g ++l+ G+ G+G ST+l
  EEA18918.1 216 DGeMMLVLGRPGAGCSTFL 234
                 5669*************98 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00077
      AAA_29  23 g.atlltGpsGsGKSTllD 40 
                 g ++ l+G+sG+GK+Tll 
  EEA18918.1 910 GvMIALMGASGAGKTTLLN 928
                 557899***********96 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0      0.11        79       2      22 ..     219     239 ..     218     244 .. 0.90
   2 !   11.2   0.2   0.00038      0.26       3      29 ..     913     939 ..     911     946 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.11
                 CEEEEC-TTTCHHHHHHHHHH CS
       NACHT   2 lvilqGeaGsGKTtLlqklal 22 
                 ++++ G++G G +t+l+ +a 
  EEA18918.1 219 MMLVLGRPGAGCSTFLKTIAN 239
                 689****************97 PP

  == domain 2  score: 11.2 bits;  conditional E-value: 0.00038
                 EEEEC-TTTCHHHHHHHHHHHHCTS-S CS
       NACHT   3 vilqGeaGsGKTtLlqklalawaegkl 29 
                 ++l G++G GKTtLl  la+  + g  
  EEA18918.1 913 IALMGASGAGKTTLLNTLAQRQKMGVV 939
                 7899***************98777665 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0      0.13        91      18      52 ..     199     236 ..     189     261 .. 0.84
   2 ?   -1.4   0.0       2.1   1.4e+03     146     168 ..     306     329 ..     299     334 .. 0.87
   3 !   10.0   0.2   0.00069      0.47      27      54 ..     904     931 ..     897     943 .. 0.88

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.13
      AAA_25  18 pppprrwlvkg...llpagelallaGapgtGKttlald 52 
                 +pp  r l+ +   +++ ge  l+ G+pg+G +t++  
  EEA18918.1 199 KPPATRTLINDftgVVRDGEMMLVLGRPGAGCSTFLKT 236
                 7888888888544499*****************99865 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 2.1
      AAA_25 146 vviDplsralggdensnsdv.gal 168
                 +++D l +++g + ++n++v ++ 
  EEA18918.1 306 IILDALLKMFGISHTKNTQVgNEY 329
                 8*****************995555 PP

  == domain 3  score: 10.0 bits;  conditional E-value: 0.00069
      AAA_25  27 kgllpagelallaGapgtGKttlaldla 54 
                  g+   g  ++l+Ga+g+GKttl+  la
  EEA18918.1 904 SGYAKPGVMIALMGASGAGKTTLLNTLA 931
                 67788899***************97776 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0      0.28   1.9e+02       1      23 [.     220     242 ..     220     272 .. 0.77
   2 ?    6.4   0.1     0.017        12       2      26 ..     914     938 ..     913     950 .. 0.86
   3 ?    1.8   0.0      0.45   3.1e+02      63      98 ..    1162    1202 ..    1152    1248 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.28
                 EEEESSTTSSHHHHHHHHHHHHT CS
         AAA   1 vllyGppGtGKTllakavakelg 23 
                 +l+ G pG G +++ k +a++ +
  EEA18918.1 220 MLVLGRPGAGCSTFLKTIANDRS 242
                 799****************9843 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.017
                 EEESSTTSSHHHHHHHHHHHHTHEE CS
         AAA   2 llyGppGtGKTllakavakelgvef 26 
                  l+G  G GKT+l + +a+  ++ +
  EEA18918.1 914 ALMGASGAGKTTLLNTLAQRQKMGV 938
                 689***************9977654 PP

  == domain 3  score: 1.8 bits;  conditional E-value: 0.45
                  EEETGGGHHHHH.....TTCCCHHHHHHHHHHHHHHHHTTT CS
         AAA   63 fiDEidalaksr.....sgseseeeervvnqLlteldgvkk 98  
                  ++DEi++++k+r     s+++++++++ ++   t+++ ++k
  EEA18918.1 1162 LLDEIEKIVKERsqipiSDDATGKQTEFAAPVTTQIEMLTK 1202
                  79**********88888777777777777777777777666 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       2.6   1.8e+03     130     153 ..     315     349 ..     204     386 .. 0.62
   2 ?   -1.2   0.0       1.7   1.2e+03      26      44 ..     912     930 ..     904     935 .. 0.87
   3 ?   11.4   0.1   0.00022      0.16     156     204 ..    1034    1082 ..     994    1094 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 2.6
                 TT-STT...........CS-HHHHHHHHHHHHHHH CS
                 xxxxxx...........xxxxxxxxxxxxxxxxxx RF
       SMC_N 130 agiske...........lLSgGektLvalaLlfAi 153
                  gis +             SgGe++ v++a  +A 
  EEA18918.1 315 FGISHTkntqvgneyvrGVSGGERKRVSIAETLAS 349
                 33333344444444444568888887777777764 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 1.7
                 EEEEEESTTSSHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxx RF
       SMC_N  26 ftaivGpNGSGKsnlldAi 44 
                 + a++G+ G+GK+ ll+ +
  EEA18918.1 912 MIALMGASGAGKTTLLNTL 930
                 56899********999876 PP

  == domain 3  score: 11.4 bits;  conditional E-value: 0.00022
                  CS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  156 vkpaplyllDeidaaLDeknvkkvaellkeksknaQfivislreemlek 204 
                  +kp+ l +lDe  + LD +    ++++l++  +  Q iv ++++     
  EEA18918.1 1034 AKPSLLLFLDEPTSGLDSQAAFSIVRFLRKLAHAGQAIVCTIHQPSSML 1082
                  68999************************************99876554 PP

>> AAA_17  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0      0.24   1.7e+02       1      37 [.     223     259 ..     223     299 .. 0.72
   2 ?   10.0   0.1    0.0013      0.87       2      31 ..     917     945 ..     916     956 .. 0.90

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.24
                 EE-TTSSHHHHHHHHHHHHTEEEEEHHHHHHHHHHTT CS
      AAA_17   1 lGgPGsGKgtqceklvekygfthlsaGdllreeakrg 37 
                 lG PG+G +t +++++ +        Gd+ +  ++ +
  EEA18918.1 223 LGRPGAGCSTFLKTIANDRSSYAAVLGDVSYGGISAE 259
                 699************9887655555566655444444 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.0013
                 E-TTSSHHHHHHHHHHHHTEEEEEHHHHHH CS
      AAA_17   2 GgPGsGKgtqceklvekygfthlsaGdllr 31 
                 G  G+GK+t++++l+++ +  +++ Gd+l 
  EEA18918.1 917 GASGAGKTTLLNTLAQRQKMGVVT-GDMLV 945
                 99*************999999887.99885 PP

>> Septin  Septin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0      0.33   2.3e+02       7      30 ..     220     243 ..     217     291 .. 0.76
   2 ?    9.5   0.1   0.00078      0.54       7      29 ..     913     935 ..     909     943 .. 0.85

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.33
                 EEEEEBTTSSCCCCCCTTSSSS-- CS
      Septin   7 lmvvGesglGkttlintlfetdli 30 
                 ++v G+ g G +t+++t+ +++  
  EEA18918.1 220 MLVLGRPGAGCSTFLKTIANDRSS 243
                 6899*************9987654 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00078
                 EEEEEBTTSSCCCCCCTTSSSS- CS
      Septin   7 lmvvGesglGkttlintlfetdl 29 
                 + ++G+sg Gkttl+ntl +++ 
  EEA18918.1 913 IALMGASGAGKTTLLNTLAQRQK 935
                 4568**************99875 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0         1   7.1e+02       7      41 ..     203     239 ..     199     247 .. 0.79
   2 ?   10.0   0.3   0.00095      0.66      19      45 ..     910     936 ..     894     941 .. 0.79

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 1
                 HHHHHHHHHHCH..TEEEEEEESTTSSHHHHHHHHHH CS
        TsaE   7 tealgkklakal..gdvilLeGdLGaGKTtlvrglak 41 
                 t++l ++++ ++  g+++l  G  GaG +t+ + +a+
  EEA18918.1 203 TRTLINDFTGVVrdGEMMLVLGRPGAGCSTFLKTIAN 239
                 566666666655677889999*************997 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00095
                 TEEEEEEESTTSSHHHHHHHHHHHTT- CS
        TsaE  19 gdvilLeGdLGaGKTtlvrglakalgv 45 
                 g +i+L G  GaGKTtl   la+  ++
  EEA18918.1 910 GVMIALMGASGAGKTTLLNTLAQRQKM 936
                 5579*****************997655 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0     0.093        64      22      46 ..     219     243 ..     209     279 .. 0.88
   2 ?   -3.0   0.0       4.7   3.2e+03     187     230 ..     326     369 ..     318     384 .. 0.70
   3 ?   -3.7   0.0       7.8   5.4e+03      93     168 ..     465     541 ..     443     545 .. 0.68
   4 ?    6.5   0.2    0.0059         4      19      43 ..     910     933 ..     897     939 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.093
                 EEEEEESTTSSHHHHHHHHCCSHCC CS
      NB-ARC  22 vvalvGmgGvGKttlakqilnksde 46 
                 ++ + G++G G +t +k i n+ ++
  EEA18918.1 219 MMLVLGRPGAGCSTFLKTIANDRSS 243
                 7999*****************9655 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 4.7
                 HHHHHHHCTT-HHHHHHHHHHHC-TCSCCHHHHHHHHHHCTGCC CS
      NB-ARC 187 akeivekckGlPlalkvlggllstkktveewkkvleklesklle 230
                 ++e v+  +G     ++++++l++k+tv  w +    l+ + + 
  EEA18918.1 326 GNEYVRGVSGGERKRVSIAETLASKSTVTCWDNSTRGLDASTAL 369
                 55555555555555567999***********9988888766554 PP

  == domain 3  score: -3.7 bits;  conditional E-value: 7.8
                 HHHHHHHCCCT.TEEEEEEEE-SHHH.H.....HHHHCHTTSEEEEEESBCCCCCCS-S-.EEEEEESS--HHHHHHHH CS
      NB-ARC  93 krklvrlLltk.rfllvlDDVweeed.wdkigvvlparenrlrvllTTRdeevanavsat.sekievelLekdeawell 168
                 +++l  + ++   +  +lDDV  ++  +      l +     + +  + ++ v+++ s t s + +v    k e w ll
  EEA18918.1 465 AEELEAVFRSSdAYKRILDDVALYKSqL--ADSQLEDTRLFQQTVGASKSRTVSKKSSYTvSFPKQVAACVKREVWLLL 541
                 5555555555555666788887665533..5666777777777777788888888888887888888888888888777 PP

  == domain 4  score: 6.5 bits;  conditional E-value: 0.0059
                 CSEEEEEEESTTSSHHHHHHHHCCS CS
      NB-ARC  19 qslvvalvGmgGvGKttlakqilnk 43 
                 + +++al+G  G GKttl++   + 
  EEA18918.1 910 G-VMIALMGASGAGKTTLLNTLAQR 933
                 5.789*************9887665 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0      0.11        79      16      40 ..     216     239 ..     210     249 .. 0.84
   2 ?   -3.3   0.0       9.2   6.3e+03      60     100 ..     373     413 ..     361     418 .. 0.61
   3 ?    7.3   0.5     0.005       3.5      18      40 ..     910     932 ..     904     939 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.11
      AAA_30  16 sgdrvavltGpAGtGKttalkalre 40 
                 +g+ ++++ G++G+G +t lk++++
  EEA18918.1 216 DGE-MMLVLGRPGAGCSTFLKTIAN 239
                 554.999**************9975 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 9.2
      AAA_30  60 kvLaeelgieastiakllkrlk....grarlepgtllivDEagmv 100
                 k L+  ++i  +t+   l++ +    +      +++l++DE  m+
  EEA18918.1 373 KSLRIMTDISRRTTFVTLYQAGegiyE----LMDKVLVIDEGRML 413
                 445555555555555555555543221....345999***98885 PP

  == domain 3  score: 7.3 bits;  conditional E-value: 0.005
      AAA_30  18 drvavltGpAGtGKttalkalre 40 
                   + +l G+ G+GKtt+l++l++
  EEA18918.1 910 GVMIALMGASGAGKTTLLNTLAQ 932
                 5677899************9976 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0     0.085        59      42      59 ..     220     237 ..     207     238 .. 0.91
   2 ?    5.9   0.2      0.01       6.9      43      59 ..     914     930 ..     904     932 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.085
                   EEEE--TTSSHHHHHHHH CS
  FtsK_SpoIIIE  42 llvaGatgsGKStalntL 59 
                   +lv+G++g G St+l+t+
    EEA18918.1 220 MLVLGRPGAGCSTFLKTI 237
                   89*************996 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.01
                   EEE--TTSSHHHHHHHH CS
  FtsK_SpoIIIE  43 lvaGatgsGKStalntL 59 
                    ++Ga+g GK+t lntL
    EEA18918.1 914 ALMGASGAGKTTLLNTL 930
                   578*************9 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0       1.2   8.3e+02      18      40 ..     219     241 ..     215     251 .. 0.81
   2 ?    8.3   0.5    0.0018       1.2      17      40 ..     911     934 ..     902     944 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 1.2
  Zeta_toxin  18 lillgGqpGAGKselaellkdel 40 
                 ++l+ G pGAG s+ ++ ++++ 
  EEA18918.1 219 MMLVLGRPGAGCSTFLKTIANDR 241
                 67899**********99998874 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.0018
  Zeta_toxin  17 klillgGqpGAGKselaellkdel 40 
                 ++i l G++GAGK++l++ l+++ 
  EEA18918.1 911 VMIALMGASGAGKTTLLNTLAQRQ 934
                 688999************999885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1534 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       911  (0.0508115); expected 358.6 (0.02)
Passed bias filter:                      628  (0.0350271); expected 358.6 (0.02)
Passed Vit filter:                       113  (0.00630264); expected 17.9 (0.001)
Passed Fwd filter:                        26  (0.00145016); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              26  [number of targets reported over threshold]
# CPU time: 1.12u 0.35s 00:00:01.47 Elapsed: 00:00:00.51
# Mc/sec: 9057.17
//
Query:       EEA18919.1  [L=486]
Description: mitochondrion biogenesis protein Mmm1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   6.5e-136  452.7   0.0   7.7e-136  452.5   0.0    1.0  1  MMM1      Maintenance of mitochondrial morphology protein 1


Domain annotation for each model (and alignments):
>> MMM1  Maintenance of mitochondrial morphology protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  452.5   0.0  4.3e-140  7.7e-136       1     330 [.      18     398 ..      18     400 .. 0.89

  Alignments for each domain:
  == domain 1  score: 452.5 bits;  conditional E-value: 4.3e-140
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXXX.XXXXX-HHH...........HHHHHHHHTTT CS
        MMM1   1 lsftqGllvGqlsvvllliifikffifgeasskeskasskaae..rlssskkklssvikkkkkekeessedleekkssnv...veessakiesiLekty 94 
                 lsftqG+l+Gqlsvvll+ +fikffifgea+++ s+  +++++  ++s s ++ ++ +++++++  + ++  e+ ++snv   v++s+++++siL+kty
  EEA18919.1  18 LSFTQGFLLGQLSVVLLIGAFIKFFIFGEAPAPPSRGLASRTAshHRSYSINQGDNNVSNNNTSGGSPRTLCEKPSTSNVlrpVPSSATNTRSILRKTY 116
                 69*********************************9998866622233344444444555555555444444444558888888999************ PP

                 --.................TTTS--B--HHHHHHHHHHHHHHHH-TT.....HHHHHHHHHHHHHH.GGCS-TTEEEEEEEEEE--S---EEEEEEE.. CS
        MMM1  95 Yd.................veshqpesLDWfnvLiaqtiaqfreeal.....ekdnilksLnealn.seelpdyldkikvteidlGedfPifsncrii. 169
                 Y+                 +++hqpesLDWfnvLiaqtiaq+r++a+      +++il+sL++a+n  +++p+++d+ikvt+i+lGe+fPifsncr+i 
  EEA18919.1 117 YNaiptqfshtkqgrhriqHSTHQPESLDWFNVLIAQTIAQYRQTAYllkdsPTSSILDSLSAAINdPQKKPSFIDTIKVTDISLGEEFPIFSNCRVIv 215
                 ***********************************************99888899***********99****************************996 PP

                 EE-TTTTSS-EEEEEEEEEE.EEEEEEEEEEEEESSSSSSEE---EEEEEEEEEEEEEEEEEE...E--SSS-........................-S CS
        MMM1 170 keskesekkrLeakidvdls.DtltlgietkLllnyPkpltavLPvalavsvvrfsgtLtvslipstkaeelv.....................keeee 246
                    ++s+++rL+a +dvdls D+l+l+iet+L+lnyPkp +avLPval+vsvvrfsgtL++slip++++++ +                     + + +
  EEA18919.1 216 VDDPNSDGGRLQALMDVDLSdDNLSLAIETSLILNYPKPRSAVLPVALSVSVVRFSGTLCISLIPAATEQSPSsaptpdasnlnvrtlfqhisaELNGT 314
                 668999**************99*******************************************9999988899*************99875433344 PP

                 --------...---S-EEEEEE-SS-EEEEEEEEESSSSTT-TTHHHHHHHHHHHHHHHHHHHHBTT-EEEEE----S--GGGE CS
        MMM1 247 eeeeeeeeeeeeeegtalvfsflpdyrldlsvksliGsrsklqdvPkiaslvearlkkWfeercvePrfqvvklPslWPrkknt 330
                 +++ +++ e++  ++t+l+fsflpdyrldlsv+sliGsrs+lqdvPk+a+lvear+++Wfeer+vePr+qvv lP++WPrk +t
  EEA18919.1 315 AANPTANPEKKGVPKTNLAFSFLPDYRLDLSVRSLIGSRSRLQDVPKVAQLVEARIHSWFEERVVEPRVQVVGLPDFWPRKGRT 398
                 44444444555559*******************************************************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (486 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       422  (0.0235373); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.44
# Mc/sec: 3318.34
//
Query:       EEA18920.1  [L=298]
Description: DUF1183 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.6e-96  322.3   0.1    6.3e-96  321.9   0.1    1.1  1  SARAF            SOCE-associated regulatory factor of calcium
     0.0038   17.9   1.2     0.0088   16.7   1.2    1.6  1  RCR              Chitin synthesis regulation, resistance to C
  ------ inclusion threshold ------
       0.24   11.5   3.9       0.23   11.6   3.0    1.5  1  DUF4719          Domain of unknown function (DUF4719)
        2.2    8.6   5.3        0.9    9.9   2.1    2.0  2  CYSTM            Cysteine-rich TM module stress tolerance
        9.2    6.7  16.4         46    4.4  16.4    2.2  1  Fungus-induced   Fungus-induced protein


Domain annotation for each model (and alignments):
>> SARAF  SOCE-associated regulatory factor of calcium homoeostasis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  321.9   0.1   1.8e-99   6.3e-96       2     331 .]      10     298 .]       9     298 .] 0.82

  Alignments for each domain:
  == domain 1  score: 321.9 bits;  conditional E-value: 1.8e-99
       SARAF   2 lllllvlataaaaakkkkdkvlLsdvqaLTLrkgrlTtaRRvspipQLkCvggsagsaaslyevdvvrCtNkGsdydgedvqWeCkadLpeelklGstd 100
                 +lll +l+t+++ + ++k++v+Ls+v++LTLr++r T++RRv+p pQLkCv g +++ ++ly++d++rCtN+G+dyd+ed+qW+C+a+Lp+e+klGstd
  EEA18920.1  10 FLLLSLLSTVLSETPPSKNAVRLSNVKTLTLRADRETSHRRVPPLPQLKCV-G-PKNVCKLYQIDTMRCTNQGYDYDEEDIQWSCTANLPSEFKLGSTD 106
                 56677778888888888**********************************.7.8******************************************** PP

       SARAF 101 ViCEGYdspdDpyvLkGSCGveYrLelteegekkykkseeskkeeekkeevkkksssssasllfvvlvllviayivykaflaaeeereaeaeggrrgeg 199
                 ViCEGY++++D+++LkGSCGveYrL lte+ge++y++ +             ++s+s++++l+f++++++v+++iv ++  ++++ ++++++g++rg+g
  EEA18920.1 107 VICEGYRNANDKWILKGSCGVEYRLLLTEKGEERYGRWR-------------DESESNTSGLIFMIIFIAVLFFIVIAISRGNNRGGDRGRRGNSRGGG 192
                 ***********************************8633.............23456677889***************999888888888888888888 PP

       SARAF 200 gggggggggpgseeeqddpPppysltksqkpssssessqqgeqeeswrpGFWtGlatGaaaGYlagrrraqneeteeeekeksssWgsssegsssssss 298
                 ggggggggg g ++++d pPppy+++  q+   s      +++++s+ pGFWtGlatG+aaGY++gr r+++++t+      +  ++         +++
  EEA18920.1 193 GGGGGGGGG-GGGDDDDYPPPPYDYQP-QY---S------QRKSSSG-PGFWTGLATGGAAGYAMGRSRNRDRQTRA-----GPYYT---------RRN 265
                 888888777.55666799*****6322.22...2......1123345.*********************97555554.....22221.........122 PP

       SARAF 299 ssssssassssssssssssstrestGFGgTrRR 331
                 ++  + +  s+  +s+s s  r++tGFG+TrRR
  EEA18920.1 266 DYDYRDDPGSAPGPSQSFSPPRSNTGFGSTRRR 298
                 2222223334444556678899**********9 PP

>> RCR  Chitin synthesis regulation, resistance to Congo red
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   1.2   2.5e-06    0.0088       4      91 ..     157     260 ..     154     292 .. 0.52

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 2.5e-06
         RCR   4 lfaiiivlillvllltlrvakrRrrrGlqplygtgWlvsa...............pppPsYgqsqqqynqaesltsatvptytpnaneedaGyydqeGk 87 
                 +++i+i+++++++++++r + r    G +  +g +  +++                ppP+Y+ ++q y+q +s  s+ +  +t  a+   aGy    G+
  EEA18920.1 157 FMIIFIAVLFFIVIAISRGNNR---GGDRGRRGNSRGGGGgggggggggggddddYPPPPYDYQPQ-YSQRKS--SSGPGFWTGLATGGAAGYAM--GR 247
                 4445555555555555555555...44444444444433223467789999***99******9877.555543..34434456666668888865..54 PP

         RCR  88 fhe.........l 91 
                   +         +
  EEA18920.1 248 SRNrdrqtragpY 260
                 4443433322221 PP

>> DUF4719  Domain of unknown function (DUF4719)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   3.0   6.3e-05      0.23      37      98 ..     152     211 ..     149     268 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 6.3e-05
     DUF4719  37 lsgllillvlfaigyflqriicpsprrynrrqarpgqrpgppggagplggarrpdddddspa 98 
                  sgl+ +++++a+ +f+   i     r   r  r   r g  gg g  gg +   dddd p 
  EEA18920.1 152 TSGLIFMIIFIAVLFFIVIAISRGNNRGGDRGRRGNSRGGG-GGGGGGGGGGGG-DDDDYPP 211
                 59999999999**9999888877766665555355555554.444444555555.4555554 PP

>> CYSTM  Cysteine-rich TM module stress tolerance
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   2.1   0.00025       0.9       1      30 [.     210     237 ..     209     239 .. 0.69
   2 ?   -2.4   0.1       1.7   6.2e+03      12      24 ..     279     292 ..     260     293 .. 0.66

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00025
       CYSTM   1 ppqpgYyqqppvqeqppqkgdgGclagCla 30 
                 pp+p+ yq p+++ q ++++++G++ g+++
  EEA18920.1 210 PPPPYDYQ-PQYS-QRKSSSGPGFWTGLAT 237
                 55666566.5666.66666699*****976 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 1.7
       CYSTM  12 vqe..qppqkgdgGc 24 
                 +++  +pp++ + G+
  EEA18920.1 279 PSQsfSPPRS-NTGF 292
                 2225667777.6665 PP

>> Fungus-induced  Fungus-induced protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4  16.4     0.013        46       3      41 ..     161     199 ..     158     206 .. 0.75

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.013
  Fungus-induced   3 vYsvfvfaiLaissVsgifkp.kggkrc.grGgsgyGsGse 41 
                     +  v++f+++ais  +   +  ++g+r  +rGg+g+G+G+ 
      EEA18920.1 161 FIAVLFFIVIAISRGNN--RGgDRGRRGnSRGGGGGGGGGG 199
                     557999*******9998..4446777777888777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (298 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       780  (0.0435049); expected 358.6 (0.02)
Passed bias filter:                      617  (0.0344135); expected 358.6 (0.02)
Passed Vit filter:                        72  (0.00401584); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 1996.28
//
Query:       EEA18921.1  [L=539]
Description: transcription factor TFIIIB component, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.7e-29   99.6   0.1    6.7e-29   99.6   0.1    2.1  3  Myb_DNA-bind_7   Myb DNA-binding like
    1.7e-08   34.5   0.0    3.7e-08   33.4   0.0    1.6  1  Myb_DNA-binding  Myb-like DNA-binding domain
  ------ inclusion threshold ------
      0.019   15.2   0.0      0.047   13.9   0.0    1.7  1  Myb_DNA-bind_6   Myb-like DNA-binding domain


Domain annotation for each model (and alignments):
>> Myb_DNA-bind_7  Myb DNA-binding like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.5         2   1.2e+04      66      85 ..     290     309 ..     284     313 .. 0.59
   2 !   99.6   0.1   1.1e-32   6.7e-29       1      85 [.     392     477 ..     392     480 .. 0.96
   3 ?   -3.1   0.4       1.3   7.7e+03      42      56 ..     489     503 ..     482     514 .. 0.51

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 2
  Myb_DNA-bind_7  66 krkeldleefkeeaekekee 85 
                     +r+e++l++++++  + ke+
      EEA18921.1 290 SRREMELRNLEQQEAERKEK 309
                     45556666666655555554 PP

  == domain 2  score: 99.6 bits;  conditional E-value: 1.1e-32
  Myb_DNA-bind_7   1 sfrkrkktkkWskeetekFYkaLsqfGtDFsliaklfpkrtrrqlKlKFkkEerknpeliekalkkrke.ldleefkeeaekekee 85 
                     ++ kr+k+++W+++ t++FY++L++fGtDFsli+k+fp+r+rrq+KlKF++Eerk+pe+i+++l  ++e +d+++++e ++++ e+
      EEA18921.1 392 TYGKRTKAESWDEDLTDLFYRGLRMFGTDFSLISKMFPGRSRRQIKLKFNNEERKDPERIKRTLLGPSEaIDIQTYSELTNTVYED 477
                     699****************************************************************999*********9998776 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 1.3
  Myb_DNA-bind_7  42 rrqlKlKFkkEerkn 56 
                     ++ + ++ ++E+r +
      EEA18921.1 489 KKRIEEQHEREKRAQ 503
                     333344444444443 PP

>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.4   0.0   6.2e-12   3.7e-08       3      44 ..     401     442 ..     399     443 .. 0.97

  Alignments for each domain:
  == domain 1  score: 33.4 bits;  conditional E-value: 6.2e-12
                      SSBHHHHHHHHHHHHHHTTCHHHHHHHHTSS-HHHHHHHHHH CS
  Myb_DNA-binding   3 kWteeEdelLleavkkhGnrWkkIaerlggRtekqcrsrwrn 44 
                      +W e+  +l++++++++G ++++I+++++gR++ q++++++n
       EEA18921.1 401 SWDEDLTDLFYRGLRMFGTDFSLISKMFPGRSRRQIKLKFNN 442
                      8***************************************98 PP

>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   7.9e-06     0.047      10      51 ..     411     452 ..     402     462 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 7.9e-06
  Myb_DNA-bind_6  10 lklvekygndWknIaealnrRtpkqcfdrwknkLrpkisrkk 51 
                      ++ +++g d+++I+++++ R+  q++ +++n+ r +++r+k
      EEA18921.1 411 YRGLRMFGTDFSLISKMFPGRSRRQIKLKFNNEERKDPERIK 452
                     566788999*********55************8888887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (539 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1748  (0.0974957); expected 358.6 (0.02)
Passed bias filter:                      506  (0.0282224); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.67u 0.30s 00:00:00.97 Elapsed: 00:00:00.43
# Mc/sec: 3807.27
//
Query:       EEA18922.1  [L=728]
Description: histone ubiquitinationc protein (Bre1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.9e-27   93.6  13.4    5.9e-27   93.6  13.4    6.9  6  BRE1            BRE1 E3 ubiquitin ligase
      3e-09   36.6   8.2    5.5e-09   35.8   8.2    1.3  1  zf-C3HC4_3      Zinc finger, C3HC4 type (RING finger)
    1.4e-08   34.4   7.4    2.7e-08   33.6   7.4    1.4  1  Prok-RING_4     Prokaryotic RING finger family 4
    3.2e-08   33.3   8.4    5.7e-08   32.5   8.4    1.4  1  zf-C3HC4_2      Zinc finger, C3HC4 type (RING finger)
    5.4e-08   32.7   5.8    1.2e-07   31.6   5.8    1.6  1  zf-RING_UBOX    RING-type zinc-finger
    2.6e-07   30.4  10.3    4.8e-07   29.5  10.3    1.5  1  zf-C3HC4        Zinc finger, C3HC4 type (RING finger)
    1.7e-06   28.2   8.9      3e-06   27.4   8.9    1.4  1  zf-RING_2       Ring finger domain
    4.2e-06   26.6  11.3    7.4e-06   25.8  11.3    1.4  1  zf-RING_5       zinc-RING finger domain
    0.00037   20.8   0.1        1.1    9.6   0.0    4.4  2  DUF2935         Domain of unknown function (DUF2935)
     0.0028   17.8   6.6     0.0053   16.9   6.6    1.5  1  zf-C3HC4_4      zinc finger of C3HC4-type, RING
  ------ inclusion threshold ------
      0.027   14.7  22.8        3.1    8.1   0.4    7.5  7  HALZ            Homeobox associated leucine zipper
       0.03   13.9   0.2       0.03   13.9   0.2    3.8  3  Trimer_CC       Trimerisation motif
      0.044   14.1   7.5       0.09   13.1   5.9    2.3  2  zf-rbx1         RING-H2 zinc finger domain
      0.069   13.3   5.7       0.15   12.2   5.7    1.5  1  DUF1272         Protein of unknown function (DUF1272)
       0.19   11.6   8.1        1.5    8.7   8.8    2.1  2  zf-RING_4       RING/Ubox like zinc-binding domain
       0.43   11.1   1.9        3.9    8.1   0.1    2.5  2  zf-H2C2_2       Zinc-finger double domain
       0.52   10.5   5.1        1.3    9.2   5.1    1.7  1  zf-UDP          Zinc-binding RING-finger
       0.54   10.4   9.8       0.38   10.9   7.0    2.2  2  zf-RING_10      zinc RING finger of MSL2
       0.76   10.1   9.7         15    6.0   0.3    3.7  3  zf-C2H2_jaz     Zinc-finger double-stranded RNA-binding
        1.6    8.9  12.4         45    4.3  12.1    2.7  2  FYVE            FYVE zinc finger
        9.1    5.5  66.6       0.33   10.2  10.1    4.5  4  DUF4407         Domain of unknown function (DUF4407)


Domain annotation for each model (and alignments):
>> BRE1  BRE1 E3 ubiquitin ligase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.2       2.2   1.9e+03      10      27 ..      74      91 ..      67     101 .. 0.65
   2 ?   -0.7   6.2       1.8   1.5e+03      10      49 ..     168     205 ..     138     235 .. 0.60
   3 ?    2.0   7.2      0.26   2.3e+02       7      47 ..     273     313 ..     272     357 .. 0.72
   4 ?   -1.5   4.3       3.1   2.6e+03       7      55 ..     329     376 ..     322     384 .. 0.59
   5 !   93.6  13.4     7e-30   5.9e-27       1      95 []     480     574 ..     480     574 .. 0.99
   6 ?    2.8   5.9      0.14   1.2e+02       5      80 ..     582     657 ..     579     674 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 2.2
        BRE1 10 kafeelseqlskkvkelt 27
                ++f+  + +l++kvke+t
  EEA18922.1 74 QEFKREKVTLESKVKEMT 91
                555555566666666555 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 1.8
        BRE1  10 kafeelseqlskkvkeltileekklrleaekakadqkyfa 49 
                 ka +e+se+ s++ k+l   eek++ +e eka  ++++f+
  EEA18922.1 168 KAVQEVSELQSQLAKKL--AEEKVTIVELEKALSERQQFE 205
                 23333333333333332..356666666666666666665 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.26
        BRE1   7 klekafeelseqlskkvkeltileekklrleaekakadqky 47 
                 +le+a++++ +  +k  ++l  le + ++l +e++    k 
  EEA18922.1 273 DLEEAYNKTLAVSQKQREQLDTLEAENAKLASEITALNVKN 313
                 6899****************************998765555 PP

  == domain 4  score: -1.5 bits;  conditional E-value: 3.1
        BRE1   7 klekafeelseqlskkvkeltileekklrleaekakadqkyfaamrskd 55 
                 +l+ ++e++ + ++ + +    l e+  +l+ae +  ++  ++a+++k+
  EEA18922.1 329 QLKSQYEDVIKRVNHLEALNVQLSEEAGKLQAERTAYRNN-MDAEKQKE 376
                 4555666666666666666666666666666666655554.35555554 PP

  == domain 5  score: 93.6 bits;  conditional E-value: 7e-30
        BRE1   1 lqkELvklekafeelseqlskkvkeltileekklrleaekakadqkyfaamrskdalenelkkLnkllsKsselieqLkelekefvrklkeleke 95 
                 l+kEL ++++  ++ s+++s+kv+++  leek +rl aek+kadqkyfaam+sk+a+++e+++L+ ++ Kss++i+qLk++e+++++++++lek+
  EEA18922.1 480 LNKELTSMQTVCKKYSSLASQKVADINVLEEKAQRLAAEKSKADQKYFAAMKSKEARDAEVRTLRLQNLKSSDIISQLKDSEAATRSLVANLEKQ 574
                 79********************************************************************************************8 PP

  == domain 6  score: 2.8 bits;  conditional E-value: 0.14
        BRE1   5 LvklekafeelseqlskkvkeltileekklrleaekakadqkyfaamrskdalenelkkLnkllsKsselieqLke 80 
                 L ++++ +++ ++q+ + v  +  l+ +++ l++ ++  d    ++  + ++ e+e+  L++ ls  +++ e+ k 
  EEA18922.1 582 LTSVSTKYRASQQQNTENVVTIDGLKAQVAELKSLMTAKDSTLASTSAACRKAEAEVESLKSTLSDTKKSLENWKT 657
                 889999*********************************************************9999999888775 PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.8   8.2   6.4e-12   5.5e-09       4      46 ..     675     717 ..     673     720 .. 0.94

  Alignments for each domain:
  == domain 1  score: 35.8 bits;  conditional E-value: 6.4e-12
                 B-TTTSSSBS-EEETTEEEEEE-HHHHHHHHH.TT-B-TTT--B CS
  zf-C3HC4_3   4 eCviClerprnvvllpCgHlvlCeeCaekllk.rkkkCpiCrrp 46 
                 +C +C ++ +n+++  CgH+ +C++C+e+ +  r++kCp C+++
  EEA18922.1 675 LCTVCRRNFKNTAIKTCGHV-FCKDCVEERQVsRSRKCPNCNKS 717
                 7*******************.********9878********986 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.6   7.4   3.1e-11   2.7e-08       1      40 [.     676     718 ..     676     723 .. 0.93

  Alignments for each domain:
  == domain 1  score: 33.6 bits;  conditional E-value: 3.1e-11
  Prok-RING_4   1 CvlCgeqekkailepCgHlvCkeCfdskdls...sCPlCqrri 40 
                  C +C+++ k+ +++ CgH++Ck+C ++ + s    CP C++ +
   EEA18922.1 676 CTVCRRNFKNTAIKTCGHVFCKDCVEERQVSrsrKCPNCNKSF 718
                  *****************************999999*****986 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.5   8.4   6.7e-11   5.7e-08       2      40 .]     676     714 ..     675     714 .. 0.95

  Alignments for each domain:
  == domain 1  score: 32.5 bits;  conditional E-value: 6.7e-11
  zf-C3HC4_2   2 CpiCldmlkdpsvvtpCgHvfCqkCilr.sLeekneCPlC 40 
                 C++C   +k++  ++ CgHvfC++C+ +   +++ +CP C
  EEA18922.1 676 CTVCRRNFKNT-AIKTCGHVFCKDCVEErQVSRSRKCPNC 714
                 **********7.**************987999999***** PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.6   5.8   1.4e-10   1.2e-07       1      39 []     676     712 ..     676     712 .. 0.92

  Alignments for each domain:
  == domain 1  score: 31.6 bits;  conditional E-value: 1.4e-10
  zf-RING_UBOX   1 CpIClelftdP.lvlpCGHtFCreClwelskslegafkCP 39 
                   C++C+  f++  ++ +CGH+FC++C+  + ++ ++++kCP
    EEA18922.1 676 CTVCRRNFKNTaIK-TCGHVFCKDCV--EERQVSRSRKCP 712
                   *********88666.5**********..7999999****9 PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.5  10.3   5.6e-10   4.8e-07       1      41 []     676     714 ..     676     714 .. 0.99

  Alignments for each domain:
  == domain 1  score: 29.5 bits;  conditional E-value: 5.6e-10
                 -TTT-S--SS-E.E-TTS--B-CHHHHHHHHCTSSB--TTT CS
    zf-C3HC4   1 CpiCleeakepnelleCkHsfCskCirkilksrkkvkCPlC 41 
                 C +C  ++k++  + +C+H fC++C+++ +  ++++kCP+C
  EEA18922.1 676 CTVCRRNFKNTA-IKTCGHVFCKDCVEERQV-SRSRKCPNC 714
                 ************.******************.999****** PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.4   8.9   3.6e-09     3e-06       3      44 .]     676     715 ..     674     715 .. 0.80

  Alignments for each domain:
  == domain 1  score: 27.4 bits;  conditional E-value: 3.6e-09
   zf-RING_2   3 CpICleelssadsvlllpCgHvfhreClerw.lrssstCPlCr 44 
                 C++C  ++++  +++++ CgHvf+++C+e+  + +s++CP+C+
  EEA18922.1 676 CTVCRRNFKN--TAIKT-CGHVFCKDCVEERqVSRSRKCPNCN 715
                 *****99974..45555.**********7743777777****5 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8  11.3   8.7e-09   7.4e-06       2      44 .]     676     716 ..     675     716 .. 0.97

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 8.7e-09
   zf-RING_5   2 CnkCfeklskeekfyltsCgHifCekClkkll.ekeavCpiCrk 44 
                 C +C++++   ++  + +CgH+fC++C+ +++  ++++Cp C+k
  EEA18922.1 676 CTVCRRNF---KNTAIKTCGHVFCKDCVEERQvSRSRKCPNCNK 716
                 ********...9999***************************86 PP

>> DUF2935  Domain of unknown function (DUF2935)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.0    0.0013       1.1      32      99 ..      69     190 ..      61     209 .. 0.87
   2 ?    4.0   0.9      0.07        60      40      87 ..     289     332 ..     191     660 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0013
     DUF2935  32 likeakefkkeFekllaeavelseglv......................................................rasseleeavakLneeal 76 
                 + ++ +efk+e  +l++++ e+++  +                                                      + ss+ ++ v+kL+ +a 
  EEA18922.1  69 IWRQMQEFKREKVTLESKVKEMTKAATfhqdhlriidawfkqlidevkilfgdddahgkdhpafqtsllfddnenfqnhlkSRSSDIKDTVSKLIANAP 167
                 5567788888888888888888888888999999999999999999999999999999999999999999999999999988889999*********** PP

     DUF2935  77 kltreliqFkkellekvlscklf 99 
                 k+++e+ +++++l +k+ + k+ 
  EEA18922.1 168 KAVQEVSELQSQLAKKLAEEKVT 190
                 ****************9998876 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.07
     DUF2935  40 kkeFekllaeavelseglvrasseleeavakLneealkltreliqFkk 87 
                 ++++++l+ae+ +l++ +    + l+ + +kL+++ ++ t+ + q+k+
  EEA18922.1 289 REQLDTLEAENAKLASEI----TALNVKNSKLTDDDYAHTDLFKQLKS 332
                 444444444444444333....23333333333333333333333333 PP

>> zf-C3HC4_4  zinc finger of C3HC4-type, RING
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   6.6   6.3e-06    0.0053       1      42 []     676     714 ..     676     714 .. 0.94

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 6.3e-06
  zf-C3HC4_4   1 CPiCldYLekPvsleCGhsfClsCisslqkepdgeqllCplC 42 
                 C +C+  +++ +   CGh+fC  C+++ q + +     Cp C
  EEA18922.1 676 CTVCRRNFKNTAIKTCGHVFCKDCVEERQVSRSR---KCPNC 714
                 99**************************999977...5*999 PP

>> HALZ  Homeobox associated leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0      0.65   5.6e+02      22      40 ..      74      92 ..      67      94 .. 0.82
   2 ?    8.1   0.4    0.0037       3.1      20      41 ..     291     312 ..     289     314 .. 0.88
   3 ?    4.2   0.7     0.061        52       7      40 ..     327     360 ..     326     363 .. 0.89
   4 ?    6.2   0.0     0.014        12      20      40 ..     432     452 ..     430     455 .. 0.87
   5 ?    3.3   0.2      0.11        94       9      27 ..     465     483 ..     462     489 .. 0.61
   6 ?    2.0   0.1      0.28   2.4e+02      30      42 ..     605     617 ..     604     618 .. 0.86
   7 ?   -2.6   0.1         8   6.8e+03      33      42 ..     636     645 ..     635     646 .. 0.75

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.65
        HALZ 22 dsLkkenekLkaelqeLke 40
                +  k+e+ +L+++++e+++
  EEA18922.1 74 QEFKREKVTLESKVKEMTK 92
                56799**********9975 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0037
        HALZ  20 dydsLkkenekLkaelqeLkek 41 
                 + d L++en kL +e+  L+ k
  EEA18922.1 291 QLDTLEAENAKLASEITALNVK 312
                 5699*************99855 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.061
        HALZ   7 YdvLKasYdaLksdydsLkkenekLkaelqeLke 40 
                 ++ LK++Y+    +++ L++ n +L  e  +L +
  EEA18922.1 327 FKQLKSQYEDVIKRVNHLEALNVQLSEEAGKLQA 360
                 578********99*******99999999999876 PP

  == domain 4  score: 6.2 bits;  conditional E-value: 0.014
        HALZ  20 dydsLkkenekLkaelqeLke 40 
                 +  sL+ e e+L++++  Lk+
  EEA18922.1 432 QISSLESEVERLRIQVDGLKD 452
                 6679***************97 PP

  == domain 5  score: 3.3 bits;  conditional E-value: 0.11
        HALZ   9 vLKasYdaLksdydsLkke 27 
                  L+ +Y +L  +y  L+ke
  EEA18922.1 465 ELRTKYQNLDRQYAMLNKE 483
                 4666666666666666665 PP

  == domain 6  score: 2.0 bits;  conditional E-value: 0.28
        HALZ  30 kLkaelqeLkekl 42 
                  Lka+++eLk+++
  EEA18922.1 605 GLKAQVAELKSLM 617
                 59********987 PP

  == domain 7  score: -2.6 bits;  conditional E-value: 8
        HALZ  33 aelqeLkekl 42 
                 ae+++Lk+ l
  EEA18922.1 636 AEVESLKSTL 645
                 7899998765 PP

>> Trimer_CC  Trimerisation motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.2   3.5e-05      0.03       7      47 ..     257     297 ..     251     300 .. 0.92
   2 ?    0.8   0.7      0.42   3.6e+02      15      35 ..     427     447 ..     412     451 .. 0.76
   3 ?   -3.6   0.0       9.8   8.3e+03      19      35 ..     628     645 ..     618     652 .. 0.59

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 3.5e-05
                 XXXXXXXXXXXXXX--HHHHHHHHHHHHHHHHHHHHHHHHH CS
   Trimer_CC   7 ratpeasgtpssdavSRLEEelrkLqatVQelQkRLDrLEe 47 
                  atp   +tps +  S LEE   k  a+ Q++ + LD LE 
  EEA18922.1 257 TATPVNGATPSPEKNSDLEEAYNKTLAVSQKQREQLDTLEA 297
                 6899999********************************95 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.42
                 XXXXXX--HHHHHHHHHHHHH CS
   Trimer_CC  15 tpssdavSRLEEelrkLqatV 35 
                 + ++  +S LE e+ +L+  V
  EEA18922.1 427 AAREAQISSLESEVERLRIQV 447
                 4566679**********9776 PP

  == domain 3  score: -3.6 bits;  conditional E-value: 9.8
                 XX--H.HHHHHHHHHHHH CS
   Trimer_CC  19 davSR.LEEelrkLqatV 35 
                  a  R  E e+  L+ t 
  EEA18922.1 628 SAACRkAEAEVESLKSTL 645
                 433331577888888776 PP

>> zf-rbx1  RING-H2 zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       4.1   3.5e+03      32      47 ..      95     110 ..      73     113 .. 0.72
   2 ?   13.1   5.9   0.00011      0.09      13      55 .]     675     715 ..     671     715 .. 0.79

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 4.1
     zf-rbx1  32 CgHaFHlhCiskWlkt 47 
                   H+ Hl  i+ W+k+
  EEA18922.1  95 TFHQDHLRIIDAWFKQ 110
                 5688999999***986 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 0.00011
     zf-rbx1  13 acieckapgdeecpvvlGeCgHaFHlhCiskW.lktrkvCPlcr 55 
                  c+ c+++ ++ + ++  +CgH+F ++C+++  ++++++CP c+
  EEA18922.1 675 LCTVCRRNFKN-TAIK--TCGHVFCKDCVEERqVSRSRKCPNCN 715
                 68889999888.4554..5**********8651666999****7 PP

>> DUF1272  Protein of unknown function (DUF1272)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   5.7   0.00017      0.15       2      48 ..     670     715 ..     669     720 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00017
     DUF1272   2 LelrpnCecCdkdlppdseearicsyEctFCaeCaeevl...envCPncg 48 
                 L+    C  C ++ ++++    i +  + FC++C+ee+    +  CPnc+
  EEA18922.1 670 LRTLALCTVCRRNFKNTA----IKTCGHVFCKDCVEERQvsrSRKCPNCN 715
                 555567999999888777....888889*******9975444679****8 PP

>> zf-RING_4  RING/Ubox like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.1       1.5   1.3e+03      38      48 .]     674     684 ..     667     684 .. 0.79
   2 ?    8.7   8.8    0.0017       1.5      19      47 ..     690     718 ..     676     719 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 1.5
   zf-RING_4  38 grCPaCreeYk 48 
                 + C  Cr+++k
  EEA18922.1 674 ALCTVCRRNFK 684
                 7899***9986 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.0017
   zf-RING_4  19 eCgyqiClfCyhrileeeegrCPaCreeY 47 
                 +Cg+ +C +C ++ + + + +CP+C + +
  EEA18922.1 690 TCGHVFCKDCVEERQVSRSRKCPNCNKSF 718
                 6***********999999*******9987 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.1      0.44   3.7e+02      17      26 .]     676     685 ..     672     685 .. 0.94
   2 ?    8.1   0.1    0.0046       3.9      16      25 ..     710     719 ..     702     720 .. 0.88

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.44
   zf-H2C2_2  17 CplCdkaFkt 26 
                 C +C+  Fk+
  EEA18922.1 676 CTVCRRNFKN 685
                 ********97 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0046
   zf-H2C2_2  16 eCplCdkaFk 25 
                 +Cp C+k+F 
  EEA18922.1 710 KCPNCNKSFG 719
                 8********7 PP

>> zf-UDP  Zinc-binding RING-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   5.1    0.0015       1.3      28      60 ..     686     718 ..     671     723 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0015
      zf-UDP  28 vacnecafpvcrpcyeyerkdgnqsCPqCktry 60 
                  a++ c+   c+ c e ++   ++ CP+C+  +
  EEA18922.1 686 TAIKTCGHVFCKDCVEERQVSRSRKCPNCNKSF 718
                 4899*************************9876 PP

>> zf-RING_10  zinc RING finger of MSL2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       3.6   3.1e+03      33      54 ..     481     502 ..     475     508 .. 0.75
   2 ?   10.9   7.0   0.00044      0.38       3      54 ..     676     723 ..     674     728 .] 0.71

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 3.6
  zf-RING_10  33 kkklkpsCsqCkdyekyeenkq 54 
                 +k+l++  + Ck+y++ + +k 
  EEA18922.1 481 NKELTSMQTVCKKYSSLASQKV 502
                 5778888889999988776665 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00044
  zf-RING_10   3 CvvCckLLvdPlepkekeCqHyvCrlCvgkkkklkp.sCsqCkdyekyeenkq 54 
                 C+vC +  ++    + k+C+H  C+ Cv +++  ++ +C++C+  +++  n  
  EEA18922.1 676 CTVCRRNFKN---TAIKTCGHVFCKDCVEERQVSRSrKCPNCN--KSFGSNDY 723
                 8999887775...45689**********999866552688887..34444444 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.3     0.017        15      11      24 ..     138     151 ..     137     152 .. 0.89
   2 ?    3.7   0.4     0.092        79       4      13 ..     676     685 ..     676     687 .. 0.95
   3 ?    4.6   0.3     0.048        41       3      13 ..     710     720 ..     708     724 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.017
                  BSSHHHHHCCTTSH CS
  zf-C2H2_jaz  11 FksenaldnHlkSK 24 
                  F + ++++nHlkS+
   EEA18922.1 138 FDDNENFQNHLKSR 151
                  78899********7 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.092
                  BTTTTBBBSS CS
  zf-C2H2_jaz   4 CvlCdKyFks 13 
                  C +C + Fk+
   EEA18922.1 676 CTVCRRNFKN 685
                  *********8 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.048
                  BBTTTTBBBSS CS
  zf-C2H2_jaz   3 YCvlCdKyFks 13 
                   C+ C+K F s
   EEA18922.1 710 KCPNCNKSFGS 720
                  6********87 PP

>> FYVE  FYVE zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3  12.1     0.053        45       9      46 ..     673     706 ..     666     717 .. 0.75
   2 ?    3.2   0.4      0.11        95       7      20 ..     706     719 ..     702     725 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.053
                 -SB-TTT--B--SSS--EE-TTT--EE-STTS-EEE.E CS
        FYVE   9 vkkCeiCakkFsllrrrhhCrlCGkvvCekCssklval 46 
                  + C+ C+++F+        ++CG+v+C++C ++++ +
  EEA18922.1 673 LALCTVCRRNFKN----TAIKTCGHVFCKDCVEERQVS 706
                 567********65....44579**********988733 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.11
                 .--SB-TTT--B-- CS
        FYVE   7 sevkkCeiCakkFs 20 
                 s+++kC++C+k+F 
  EEA18922.1 706 SRSRKCPNCNKSFG 719
                 67899*******94 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2  10.1   0.00039      0.33     121     237 ..     174     317 ..     142     322 .. 0.76
   2 ?    1.2  18.2      0.22   1.9e+02     140     234 ..     342     424 ..     321     429 .. 0.50
   3 ?   -1.7  28.4       1.7   1.5e+03     116     260 ..     406     623 ..     398     626 .. 0.59
   4 ?    2.5   9.8     0.086        74     128     208 ..     558     656 ..     531     675 .. 0.54

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00039
     DUF4407 121 kelkeqlaaa.............ltaelaeleaqiaalqaeidaaearldalraeaqkeldgtk..gtgttgvaGkgpaake................k 188
                 +el++qla++             + +e ++ e+q++a++  +  ae++ld++r    ++l+ +   g++  +  G+gp+  +                k
  EEA18922.1 174 SELQSQLAKKlaeekvtivelekALSERQQFEEQLEAASLRYMMAEKKLDRARSMTVAKLEKQYilGAQ--RPGGDGPSSATredtatpvngatpspeK 270
                 333333333344446666666677788899999999999999999999999999999999988855555..5668888888866888888888888887 PP

     DUF4407 189 kaqldaaqaelaelkakldatarlaalraelaeleaerakeraasqaaa 237
                 +++l++a ++  ++++k  ++++l++l+ae a+l++e+++ + ++ + +
  EEA18922.1 271 NSDLEEAYNKTLAVSQK--QREQLDTLEAENAKLASEITALNVKNSKLT 317
                 77777776666666666..899***********9999999888877655 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.22
     DUF4407 140 aqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaakekkaqldaaqaelaelkakldatarlaalraelaeleaerakeraasq 234
                 + ++al+ ++++   +l+a+r+++++++          +a k ++ +ek+aql++a+ +la +++   +++ la+++ ++a+ e+e +++ +a++
  EEA18922.1 342 NHLEALNVQLSEEAGKLQAERTAYRNNM----------DAEKQKEIEEKDAQLQKAESDLARIRNA--RDELLADQQMRKASQEQESTAASKAQE 424
                 2223333344444444444444444333..........4445567788999999999999999999..555555555555554444444433333 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 1.7
     DUF4407 116 qqeeakelkeqlaaa.ltaelaeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaakekkaqldaaqaelaelkakld...... 207
                 q ++a++ +e++aa+ +++  a+ eaqi++l++e++ ++ ++d l+++ +++l+g +      v+   + +++ ++q++ +++el+++++  +      
  EEA18922.1 406 QMRKASQEQESTAASkAQELAAAREAQISSLESEVERLRIQVDGLKDDTAEHLEGLS------VEELRTKYQNLDRQYAMLNKELTSMQTVCKkyssla 498
                 444444444444444344444444555555555555555555555555555555432......222233344444444444444444444433444444 PP

     DUF4407 208 ........................................................................atarlaalraelaeleaerakeraasq 234
                                                                                          ++++a+ ++ l+++ +++++++++++
  EEA18922.1 499 sqkvadinvleekaqrlaaekskadqkyfaamkskeardaevrtlrlqnlkssdiisqlkdseaatrslvanLEKQIAEGKEALTSVSTKYRASQQQNT 597
                 443333333333333444444566677777777777777777777777777788888888888888888888889999999999999999999999999 PP

     DUF4407 235 aaaaaddGllarlealdrltkedata 260
                 +     dGl a+   l+ l +++++ 
  EEA18922.1 598 ENVVTIDGLKAQVAELKSLMTAKDST 623
                 99999999999999998888877765 PP

  == domain 4  score: 2.5 bits;  conditional E-value: 0.086
     DUF4407 128 aaa...ltaelaeleaqiaalqaeidaaearldalraeaqkeldgtk..............gtgttgvaGkgpaakekkaqldaaqaelaelkakld.. 207
                 +++    ++ +a+le+qia+ ++++++ +++++a +++ ++++                  +++ +  a   +a+++++a+ + ++ +l + k++l+  
  EEA18922.1 558 KDSeaaTRSLVANLEKQIAEGKEALTSVSTKYRASQQQNTENVVT-IdglkaqvaelkslmTAKDSTLASTSAACRKAEAEVESLKSTLSDTKKSLEnw 655
                 222333566667777777777777777777766666666655543.22343444444444444444444445555555555555555555555544444 PP

     DUF4407 208 a 208
                 +
  EEA18922.1 656 K 656
                 4 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (728 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2985  (0.16649); expected 358.6 (0.02)
Passed bias filter:                      536  (0.0298957); expected 358.6 (0.02)
Passed Vit filter:                       149  (0.00831056); expected 17.9 (0.001)
Passed Fwd filter:                        85  (0.00474092); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              21  [number of targets reported over threshold]
# CPU time: 1.77u 0.38s 00:00:02.15 Elapsed: 00:00:00.59
# Mc/sec: 3716.72
//
Query:       EEA18923.1  [L=309]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.8e-24   86.2   0.6    7.6e-24   84.8   0.6    1.6  1  UreF      UreF
  ------ inclusion threshold ------
       0.14   12.2   0.1       0.29   11.3   0.1    1.5  1  Med9      RNA polymerase II transcription mediator complex su
       0.16   12.1   0.0       0.36   11.0   0.0    1.5  1  DUF826    Protein of unknown function (DUF826)


Domain annotation for each model (and alignments):
>> UreF  UreF
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.8   0.6   1.3e-27   7.6e-24       7     130 ..     100     263 ..      98     265 .. 0.91

  Alignments for each domain:
  == domain 1  score: 84.8 bits;  conditional E-value: 1.3e-27
                 HHHHHHHHHTTHHHHTHHHHHHHHHHHHHTT-HHHHHHHHHHHHHH--SHHHHHHHHHHHHHHHHHHHH-............................. CS
        UreF   7 laawledqLllglarldlavlarayraaragdaaalrelddwllatretaelrlaseqmGrsllrllrkl............................. 76 
                 ++++l+ +   +++r+ l++l++ayra      a+l+ ld+ l+a++++ ++r+as+++Gr+l+ +++k                              
  EEA18923.1 100 FRKFLKLS-ISSVSRTSLPYLLAAYRAP-----AELETLDNDLDASTPCTVARRASVAQGRALISVWEKSfrpsyiltgnaanqlgadpqsavaaieef 192
                 78899999.899**************99.....5*****************************************999999999999888887777766 PP

                 ..................-HHHHHHHHHHHHT--HHHHHHHHHHHHHHHHHHHHHHHTT--HHHHHHHHHH CS
        UreF  77 .....t............hypvafglaaaalgipleeallaylfswaenlvsAavklvplGqtagqrilar 130
                                   h++ ++g+++aa+gi+   +++ ++ ++a++++sAav++  +G++++q+ la+
  EEA18923.1 193 sealkMsgydneslgpngHFAPLWGVVCAAMGIEIGLTAYTFMLNHAKAVLSAAVRASVMGPYQAQTFLAS 263
                 666550556666778899*************************************************9985 PP

>> Med9  RNA polymerase II transcription mediator complex subunit 9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   4.8e-05      0.29      23      52 ..       8      40 ..       2      48 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 4.8e-05
        Med9 23 dletktgelrhkLkkarelirelpg...idrsv 52
                +l++++ el ++Lk+ar+ +re +g    ++s+
  EEA18923.1  8 ELQNEIRELELRLKNARSRLRETHGnvaYEESP 40
                7899******************99975555555 PP

>> DUF826  Protein of unknown function (DUF826)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0     6e-05      0.36      16      51 ..     260     297 ..     256     299 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 6e-05
      DUF826  16 aLrSeeVrkalKaklrkdlesqiD..aeVDavLaeLlG 51 
                  L S+e+r+++ +++r+d++++    ++V  vL+  lG
  EEA18923.1 260 FLASNEIRNLINERIRHDFDTRPEdaGQVAPVLDLWLG 297
                 589*****************996423467777776666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       557  (0.031067); expected 358.6 (0.02)
Passed bias filter:                      514  (0.0286686); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.30s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 2101.97
//
Query:       EEA18924.1  [L=733]
Description: molecular chaperone (ABC1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.9e-35  119.4   0.0    2.8e-34  117.8   0.0    1.9  2  ABC1      ABC1 family
  ------ inclusion threshold ------
      0.042   13.2   0.0       0.32   10.3   0.0    2.1  2  Pkinase   Protein kinase domain


Domain annotation for each model (and alignments):
>> ABC1  ABC1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0         1     9e+03      76     107 ..      33      65 ..       9      69 .. 0.53
   2 !  117.8   0.0   3.1e-38   2.8e-34       2     118 ..     408     524 ..     407     525 .. 0.97

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 1
        ABC1  76 leelvdefskslleEld.ferEAknaekfrenf 107
                 + + +  ++k l++++d +   A++a+ ++++f
  EEA18924.1  33 VFTRTSSLTKGLKQQVDnLVITAQAASALARRF 65 
                 344444555666666652344555555555555 PP

  == domain 2  score: 117.8 bits;  conditional E-value: 3.1e-38
        ABC1   2 elgkkleeiFaefdeePiAaASiaqVhrAklk.sgeeVavKvqrpgvkkriksDlellkllakllkkflkelrldleelvdefskslleEldferEAkn 99 
                 +lg +++++F++f+e P+AaASi+qVh A+lk +g++Va+K+q+pgv+++i+sDl++l++l+++++ ++k+l+  l++++++++++l++E+d+erEA+ 
  EEA18924.1 408 NLGPNWRDLFESFEEIPMAAASIGQVHGAVLKkDGRRVAIKIQYPGVADSIDSDLNNLSILLTATRLLPKGLF--LDKTIANARTELAWECDYEREAQC 504
                 6899****************************99***************************************..************************ PP

        ABC1 100 aekfrenfaklke.vkvPkv 118
                 ae+fr+ +++++  + vP++
  EEA18924.1 505 AERFRDLLKDDSSsFVVPEI 524
                 **********9955****98 PP

>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0      0.06   5.4e+02      12      32 ..     430     450 ..     427     466 .. 0.86
   2 ?   10.3   0.0   3.5e-05      0.32      72     155 ..     531     611 ..     486     620 .. 0.76

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.06
                 SEEEEEEEETTTTEEEEEEEE CS
     Pkinase  12 fGkVykaveketgkivAvKki 32 
                  G+V  av k++g+ vA+K+ 
  EEA18924.1 430 IGQVHGAVLKKDGRRVAIKIQ 450
                 79*****************85 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 3.5e-05
                 EEEEEEE--TTEBHHHHHHHHSS--HHHHHHHHHHHHH.HHHHHHHTTEE-SS-SGGGEEEE.TTTEEEE-SGTTSEESSSSCSBC CS
     Pkinase  72 elylvleyveggeladllerkgslseeeakkiakqile.gleylHskgiiHrDlKpeNiLid.ekgelKitDFGlakelesssklt 155
                 + +l +e ++g  ++    + +++++e+  +i ++il+  l+ + + +++  D    N+L++ ek+ l + DFG ++e+ s+   +
  EEA18924.1 531 KQVLTMERMDGIAVT----KIKNFTQEQRDRIGTEILRlCLREIVEFRFMQTDPNWTNFLYNaEKNRLELLDFGASREYPSDF-IE 611
                 334555555544333....44569999999**999998689*********************88888**********998864.55 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (733 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       515  (0.0287244); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.47
# Mc/sec: 4687.91
//
Query:       EEA18925.1  [L=473]
Description: Snf1 kinase complex beta-subunit Gal83, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.9e-29  100.7   0.2    6.9e-29   99.9   0.2    1.4  1  AMPK1_CBM  Glycogen recognition site of AMP-activated protein
    1.1e-24   86.4   1.0    4.1e-24   84.6   1.0    2.0  1  AMPKBI     5'-AMP-activated protein kinase beta subunit, inte
  ------ inclusion threshold ------
        1.9    8.6   5.6        5.6    7.1   0.1    2.7  2  UIM        Ubiquitin interaction motif


Domain annotation for each model (and alignments):
>> AMPK1_CBM  Glycogen recognition site of AMP-activated protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.9   0.2   1.2e-32   6.9e-29       1      84 [.     224     310 ..     224     311 .. 0.95

  Alignments for each domain:
  == domain 1  score: 99.9 bits;  conditional E-value: 1.2e-32
   AMPK1_CBM   1 vptvikWkggGkkVyvtGsfnnWkkkipLk...ksekdfsvilkLpeGthqykFiVDgewrvdpdlptatdeeGnlnNvievkesdl 84 
                 vptvi+Wkg G++V+vtG+f nW+kk++L+   +++++ s++l+L++Gth++kFiVDg++r ++dlpta d +++l+N+iev ++dl
  EEA18925.1 224 VPTVIEWKGTGDRVFVTGTFVNWEKKFRLHksdTEPNVKSTTLHLRPGTHHLKFIVDGDMRASDDLPTAVDFTNHLVNYIEVVADDL 310
                 79****************************766567999*******************************************98876 PP

>> AMPKBI  5'-AMP-activated protein kinase beta subunit, interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.6   1.0   6.8e-28   4.1e-24       3      75 .]     400     468 ..     398     468 .. 0.97

  Alignments for each domain:
  == domain 1  score: 84.6 bits;  conditional E-value: 6.8e-28
      AMPKBI   3 keppklPphLekvllnkssdsaassaddssvlpiPnhvvLnHLltssikngvlavgcttRYrkKyvTtvlYkP 75 
                  +pp lP  L + +ln     ++ ++dd+svl  Pnh vLnHL+tssikngvla ++ttRY++KyvTt+lYkP
  EEA18925.1 400 TTPPILPLFLGRSILNG----TTPMKDDNSVLNYPNHTVLNHLATSSIKNGVLATSVTTRYKRKYVTTILYKP 468
                 68***************....899************************************************9 PP

>> UIM  Ubiquitin interaction motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.1   0.00093       5.6       2      10 ..     208     216 ..     208     217 .. 0.93
   2 ?    2.6   1.6     0.026   1.5e+02       1       9 [.     384     392 ..     384     392 .. 0.96

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.00093
         UIM   2 EdedLqrAl 10 
                 Ede+L++A+
  EEA18925.1 208 EDEMLAYAM 216
                 9*******9 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.026
         UIM   1 dEdedLqrA 9  
                 dEde+ qrA
  EEA18925.1 384 DEDEEYQRA 392
                 8*******9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (473 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       438  (0.0244297); expected 358.6 (0.02)
Passed bias filter:                      297  (0.0165653); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 3155.93
//
Query:       EEA18926.1  [L=200]
Description: hypothetical protein PMAA_011980 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (200 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       643  (0.0358637); expected 358.6 (0.02)
Passed bias filter:                      385  (0.0214736); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.28s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 1367.85
//
Query:       EEA18927.1  [L=362]
Description: O-sialoglycoprotein endopeptidase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.1e-83  278.4   0.0    1.1e-82  277.8   0.0    1.3  1  Peptidase_M22   Glycoprotease family
  ------ inclusion threshold ------
      0.097   12.3   0.1       0.77    9.3   0.0    2.0  2  Carbam_trans_N  Carbamoyltransferase N-terminus


Domain annotation for each model (and alignments):
>> Peptidase_M22  Glycoprotease family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  277.8   0.0   1.2e-86   1.1e-82       2     270 ..      29     327 ..      28     328 .. 0.95

  Alignments for each domain:
  == domain 1  score: 277.8 bits;  conditional E-value: 1.2e-86
                    CEXEEEEEEEEE....S.SSSHHHHHHHHHHHHHHHHHHHHHHHTSTGGGEEEEEEEEESS-HHHHHHHHHHHHHHHHHCT--EEEEEHHHHHHHC CS
  Peptidase_M22   2 vlanvvasqkelhakyG.GvvPelasraHserllplieealaeaglsledldaIavtkgPGlftgLrvGvsfAkglalalnkPlvgVnhleahala 96 
                    vlanv ++++   a++G G++P++++++H+ ++++l+++al ea +s++d+d+I++tkgPG++ +L+  + +A++l+l ++k lvgVnh+ +h+++
     EEA18927.1  29 VLANVRHTYN---APPGeGFLPKDTAQHHRAWVVKLVKQALVEARISVDDVDCICYTKGPGMGAPLQSTAVAARMLSLLWGKDLVGVNHCVGHIEM 121
                    7888888887...99999****************************************************************************** PP

                    CHCTSECSSCEEEEESSSTEEEEEECTTEEEEEEEESSSEHHHHHHHHHHHHT..SSCCH..HHHHHHCTC.S.......EETTEEE.CHHHHHHH CS
  Peptidase_M22  97 arleekeefPvvllvsGghtqvylvkegryeilgetlddaagealdkvarllglpypggp..kieklakeg.kkiefprplkgldfsfsGlktavl 189
                    +r  ++ ++Pvvl+vsGg+tqv++++++ry+i+getld+a+g++ld++ar+l +p+++ p  +ie+lak+g + +e+p+++kg+d+sfsG+ + v 
     EEA18927.1 122 GRQVTGATNPVVLYVSGGNTQVIAYSSKRYRIFGETLDIAVGNCLDRFARTLCIPNDPAPgyNIEQLAKKGkRLVEMPYTVKGMDCSFSGILAHVD 217
                    **669889*****************99*****************************777777*********666*******************999 PP

                    HHHST.T............................HHHHHHHHHHHHHHHHHHHHHHHHHHCTBSEEEEESGGGGXHHHHHCHCCHHHHTTSEEEX CS
  Peptidase_M22 190 kelek.e............................vedlaasfqeavvdhlvekteralklpkakelvilGGvaankrLrealeeeaeelglklii 256
                     ++++                              ++dl++s+qe++ ++lve+tera+++ +a++++i+GGv++n+rL+e+++ +a+++g  l++
     EEA18927.1 218 GLATSlGlsghaaaaldeldqtdsngdadasdkitRADLCFSLQETIYAMLVEITERAMAHVGAQDVLIVGGVGCNERLQEMMSLMARDRGGYLYA 313
                    999665357899999*********************************************************************99999******* PP

                    XXHHHHSSXCHHHH CS
  Peptidase_M22 257 Pplkyctdnaamia 270
                    ++++yc dn++mia
     EEA18927.1 314 TDERYCIDNGIMIA 327
                    *************8 PP

>> Carbam_trans_N  Carbamoyltransferase N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0     0.043   3.9e+02      46      71 ..      60      85 ..      48      95 .. 0.82
   2 ?    9.3   0.0   8.6e-05      0.77     266     305 ..     250     293 ..     223     303 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.043
  Carbam_trans_N 46 kaidyaleeagvelsdiDqivfdeid 71
                    k ++ al ea ++  d+D+i + + +
      EEA18927.1 60 KLVKQALVEARISVDDVDCICYTKGP 85
                    57899999************998765 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 8.6e-05
  Carbam_trans_N 266 e....dlaAsiqvflErlvvevlnivyeklkirnLclaGGvalN 305
                     +    dl  s+q+ +  ++ve ++ ++++++++   + GGv+ N
      EEA18927.1 250 KitraDLCFSLQETIYAMLVEITERAMAHVGAQDVLIVGGVGCN 293
                     244459************************************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (362 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       325  (0.0181271); expected 358.6 (0.02)
Passed bias filter:                      301  (0.0167884); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.36s 00:00:01.03 Elapsed: 00:00:00.59
# Mc/sec: 1861.00
//
Query:       EEA18928.1  [L=481]
Description: SET domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-21   77.4   0.0    4.1e-21   76.1   0.0    1.7  2  SET              SET domain
    8.3e-15   55.6   3.4    2.1e-14   54.4   1.6    2.2  2  Rubis-subs-bind  Rubisco LSMT substrate-binding


Domain annotation for each model (and alignments):
>> SET  SET domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.1   0.0   4.5e-25   4.1e-21       1     169 []      47     275 ..      47     275 .. 0.85
   2 ?   -1.9   0.0      0.41   3.7e+03      22      43 ..     409     451 ..     347     480 .. 0.58

  Alignments for each domain:
  == domain 1  score: 76.1 bits;  conditional E-value: 4.5e-25
                 SCEEEESSXBXTTXEEEEEEECCEECHHHHHHHHHH..............................HTEEEEEXGGXX.GGSX.HHHHHHHTTSSHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..............................xxxxxxxxxxxx.xxxx.xxxxxxxxxxxxxxx RF
         SET   1 GrGvfAtedIpkgeficeypeeiiltkdeadksele..............................aylfslpeapkn.laft.kelakasastllqkl 67 
                 GrGv+A+ +I++ge ++ +p++i+l   ++++++                                +y++ lp+++ + ++++ +e  +++as  ++k 
  EEA18928.1  47 GRGVVARSNIQEGEDLFHLPHHIVLMVKTSRLNQILaddlknlgpwlslvvvmiyeyslgeqsnwkQYFQVLPSKFDTlMFWSeEEFSQLQASAVVDKV 145
                 9*********************************99*************************************88777677779*************99 PP

                 HHHHHHHHHHHHHHTHHHHHHHXTTTS......X..........XXHCCCCC.HCCCHEEEETEEEEEECCC.................GTTGGGCEEX CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx......x..........xxxxxxxx.xxxxxxxxxxxxxxxxxxx.................xxxxxxxxxx RF
         SET  68 akdqkqaekedtdaalkasskaesdln......a..........skpeagaf.saiagysidaralksgnga.................gplarflNHs 132
                 +k++++   ed   ++   + a+ dl       +            ++a    s+i+ y++d +  ++ + +                 +pla++lN +
  EEA18928.1 146 GKRDAE---EDIFEKVLPLVRAHPDLFppidgvMsydddtgaqaLLELAHRMgSLIMAYAFDIEKAEEEESEgedgyltddeeqlpkgmVPLADLLNAD 241
                 987765...67777888888888888877777625666777765333333347999999999333333333355778889999999999********** PP

                 SSSSEEEEEEEETTSSEEEEEESSXBXTTEEEEEXTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         SET 133 CdpNcnltvqnvlrgprvavfAtrdIkkGeEltidYg 169
                  d N +  +q    ++ ++++A+++Ik+G+E+++dYg
  EEA18928.1 242 ADRNNARLFQE---EGALVMRAIKPIKAGDEIFNDYG 275
                 *9999999999...**********************8 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.41
                 CCEECHHHHHHHHHH.....................HTEEEEE CS
                 xxxxxxxxxxxxxxx.....................xxxxxxx RF
         SET  22 eiiltkdeadksele.....................aylfslp 43 
                  +il +++a+ s+l                      a+l++l+
  EEA18928.1 409 DKILLQQFASSSVLRtrerrrhmavqvrvgekeilqALLMMLQ 451
                 3344444444444444444444444565555555554444444 PP

>> Rubis-subs-bind  Rubisco LSMT substrate-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.0      0.14   1.2e+03      29      57 ..     218     249 ..     181     270 .. 0.69
   2 !   54.4   1.6   2.3e-18   2.1e-14      11     129 .]     324     443 ..     317     443 .. 0.81

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.14
  Rubis-subs-bind  29 e......egipeeLlaylrvllasekdakeleela 57 
                      +      e++p+++++ + +l+a   da+   + +
       EEA18928.1 218 GyltddeEQLPKGMVPLADLLNA---DADRNNARL 249
                      04445568999999999999999...555444444 PP

  == domain 2  score: 54.4 bits;  conditional E-value: 2.3e-18
  Rubis-subs-bind  11 qlLerhglpstqefplkle......egipeeLlaylrvllasekdakeleelaskeedsglaseplsddnEaaalrllldrckalLsaypttle 98 
                      +lL + ++ +   + l+ +      + +p+eLla l+ l +   d++el++l+sk+      + p +    a+  r lld++++ + +y+tt++
       EEA18928.1 324 KLLDQLEILEDGYCILRPSpedtllDILPDELLALLKTLTL---DSEELQRLLSKN------KHPKPILG-AREARILLDAAQSKMGQYGTTIQ 407
                      566666665555555555566666699**************...**********96......45666666.777999***************** PP

  Rubis-subs-bind  99 eDeellkdadaavtn.....rerlavqlrvgEkrIL 129
                      eD+ ll++  ++        r+ +avq+rvgEk+IL
       EEA18928.1 408 EDKILLQQFASSSVLrtrerRRHMAVQVRVGEKEIL 443
                      ******99877765567666666************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (481 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       584  (0.0325729); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.29s 00:00:00.89 Elapsed: 00:00:00.48
# Mc/sec: 2989.70
//
Query:       EEA18929.1  [L=582]
Description: histone acetyltransferase complex component Epl1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-21   77.3   0.3    1.6e-21   77.3   0.3    3.0  3  EPL1      Enhancer of polycomb-like
  ------ inclusion threshold ------
        3.2    6.3  16.5        6.4    5.3  16.5    1.4  1  Med15     ARC105 or Med15 subunit of Mediator complex non-fun


Domain annotation for each model (and alignments):
>> EPL1  Enhancer of polycomb-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.3   0.3   1.8e-25   1.6e-21       1     156 [.      11     153 ..      11     154 .. 0.80
   2 ?   -3.2   2.9       1.1     1e+04      60      69 ..     362     371 ..     271     494 .. 0.56
   3 ?   -2.3   5.9      0.57   5.1e+03      26      74 ..     500     550 ..     479     571 .. 0.43

  Alignments for each domain:
  == domain 1  score: 77.3 bits;  conditional E-value: 1.8e-25
        EPL1   1 rqprldikkkLkviseeevdgldeseseeeiseknsnkensqqavetgvdkkeenekh.q.viaaakkkesssasske.........slkkeelkLpkP 88 
                 r ++l+ k+++++++e+++d +de+ ++            + q+vetgv+k ee+e h q +i+a    + s+a+  +         +      +L  P
  EEA18929.1  11 RPKKLTSKASIPIVREDQIDAIDEDVQS------------ALQQVETGVEKAEESEFHlQaAINAVALGKISEANIPTpetvlsnirY-----DELYPP 92 
                 568999***********99999855332............3577899***********887777766555444444335555433322.....566666 PP

        EPL1  89 sfreferppssyirfsekseeelddeveYdMDEeDekWLeelnekrkkegvekisediFEivmdrlEk 156
                 +f +    p++yirfs+++e+++  ++ Y++DEeD+ +L+ +nekr  + + +++ed+FE vm  +E+
  EEA18929.1  93 TFSQ----PATYIRFSSTVEDCC--GCMYNLDEEDDVYLKIMNEKRDPS-TPACTEDQFEEVMYFFEE 153
                 8888....***************..********************6655.****************97 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 1.1
        EPL1  60 viaaakkkes 69 
                 +i + k + +
  EEA18929.1 362 IIRDIKLNLQ 371
                 2222222222 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 0.57
        EPL1  26 eseeeiseknsnkens..qqavetgvdkkeenekh.q..viaaakkkesssass 74 
                 +++ +i+  +++   +      e  + + ++ ++h q  + aaa+++++++a++
  EEA18929.1 500 RDKYDIQVMQHRAIMAakA--REVAQMQAQA-QAHaQaqAQAAAQAAAQAQAQT 550
                 4444444333333333221..1111111111.1121111222222222222222 PP

>> Med15  ARC105 or Med15 subunit of Mediator complex non-fungal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3  16.5   0.00071       6.4     255     305 ..     507     556 ..     497     579 .. 0.48

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.00071
       Med15 255 ldqvrgpadaqaqmqqqaqanagmnpqqmagaqaqvarqqqqaqqqaqqsq 305
                 + q r  + a+a+  +q qa+a++++q++a+a aq   +q+qaq+q+  + 
  EEA18929.1 507 VMQHRAIMAAKAREVAQMQAQAQAHAQAQAQAAAQA-AAQAQAQTQTARQM 556
                 444444555555444444444444444444444442.22222222222111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (582 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2309  (0.128786); expected 358.6 (0.02)
Passed bias filter:                      672  (0.0374812); expected 358.6 (0.02)
Passed Vit filter:                        67  (0.00373696); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.74u 0.33s 00:00:01.07 Elapsed: 00:00:00.48
# Mc/sec: 3625.55
//
Query:       EEA18930.1  [L=192]
Description: calcineurin Ca2+-binding regulatory subunit CnaB [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.9e-28   93.9  11.2    2.7e-08   32.8   0.9    4.3  4  EF-hand_1     EF hand
    8.2e-23   80.6   6.0    1.2e-13   51.3   1.7    2.4  2  EF-hand_7     EF-hand domain pair
    6.2e-21   72.5   5.9    0.00012   21.8   0.0    4.4  4  EF-hand_6     EF-hand domain
    6.2e-19   66.6   9.7    5.6e-07   28.8   0.3    4.4  4  EF-hand_5     EF hand
    3.3e-13   49.3  11.3    9.8e-05   22.1   0.5    4.4  5  EF-hand_8     EF-hand domain pair
    2.1e-06   28.0   0.0     0.0028   17.9   0.1    2.3  2  SPARC_Ca_bdg  Secreted protein acidic and rich in cysteine Ca
    0.00011   22.1   8.6       0.15   12.0   0.5    4.0  4  EF-hand_4     Cytoskeletal-regulatory complex EF hand
  ------ inclusion threshold ------
      0.049   14.0   0.1       0.84   10.0   0.1    2.6  3  EF-hand_9     EF-hand domain


Domain annotation for each model (and alignments):
>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.3   0.0   6.4e-09   1.4e-05       2      25 ..      44      67 ..      43      69 .. 0.92
   2 !   18.6   0.1   4.1e-07   0.00092       4      28 ..      78     102 ..      77     103 .. 0.92
   3 !   23.3   0.2   1.2e-08   2.8e-05       2      29 .]     113     140 ..     112     140 .. 0.91
   4 !   32.8   0.9   1.2e-11   2.7e-08       2      27 ..     154     179 ..     153     181 .. 0.92

  Alignments for each domain:
  == domain 1  score: 24.3 bits;  conditional E-value: 6.4e-09
                HHHHHHHHTTTSSSEEEHHHHHHH CS
   EF-hand_1  2 lkeiFrefDkDgdGkIdfeEfkel 25
                l++ F+++DkD++G+I++eEf++l
  EEA18930.1 44 LRKRFMKLDKDNSGTIEREEFLSL 67
                7899*****************875 PP

  == domain 2  score: 18.6 bits;  conditional E-value: 4.1e-07
                 HHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1   4 eiFrefDkDgdGkIdfeEfkellkk 28 
                 +++++fD Dg G +df+Ef++ l++
  EEA18930.1  78 RMIAIFDEDGGGDVDFQEFVSGLSA 102
                 699*****************99875 PP

  == domain 3  score: 23.3 bits;  conditional E-value: 1.2e-08
                 HHHHHHHHTTTSSSEEEHHHHHHHHHHH CS
   EF-hand_1   2 lkeiFrefDkDgdGkIdfeEfkellkkl 29 
                 l  +F+++D D+dG+I+  E+  +lk++
  EEA18930.1 113 LHFAFKVYDIDRDGYISNGELFIVLKMM 140
                 6789*****************9999875 PP

  == domain 4  score: 32.8 bits;  conditional E-value: 1.2e-11
                 HHHHHHHHTTTSSSEEEHHHHHHHHH CS
   EF-hand_1   2 lkeiFrefDkDgdGkIdfeEfkellk 27 
                 +++ ++e+DkD+dGkI+feEfk++++
  EEA18930.1 154 VDKTIMEADKDHDGKISFEEFKNMVE 179
                 7999*******************986 PP

>> EF-hand_7  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.5   0.2   8.1e-11   1.8e-07       3      68 ..      43      98 ..      25     101 .. 0.94
   2 !   51.3   1.7   5.4e-17   1.2e-13       1      70 [.     110     178 ..     110     179 .. 0.87

  Alignments for each domain:
  == domain 1  score: 31.5 bits;  conditional E-value: 8.1e-11
   EF-hand_7  3 klkeaFkelDtdgdgyldkeellrllrkifqgagegsklsdeelellfkefDtdkdGvisfdEFlk 68
                +l+ +F +lD+d++g +++ee+l+l +         ++l +    +++  fD d+ G ++f+EF+ 
  EEA18930.1 43 RLRKRFMKLDKDNSGTIEREEFLSLPQ------VSSNPLAP----RMIAIFDEDGGGDVDFQEFVS 98
                7999*****************997888......99999999....*******************85 PP

  == domain 2  score: 51.3 bits;  conditional E-value: 5.4e-17
   EF-hand_7   1 eeklkeaFkelDtdgdgyldkeellrllrkifqgagegsklsdeelellfkef....DtdkdGvisfdEFlkly 70 
                 +ekl+ aFk +D d+dgy++  el  +l+        gs+l d +l++++++     D+d+dG+isf+EF++++
  EEA18930.1 110 DEKLHFAFKVYDIDRDGYISNGELFIVLKM-----MVGSNLKDVQLQQIVDKTimeaDKDHDGKISFEEFKNMV 178
                 589********************9989998.....9999999977666666555555*************9986 PP

>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   0.0   5.2e-08   0.00012       1      24 [.      43      66 ..      43      70 .. 0.92
   2 !   11.6   0.1   9.5e-05      0.21       8      27 ..      82     101 ..      80     107 .. 0.90
   3 !   21.4   0.1   6.6e-08   0.00015       2      28 ..     113     139 ..     112     146 .. 0.89
   4 !   17.8   0.1   9.6e-07    0.0021       9      27 ..     161     179 ..     156     185 .. 0.89

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 5.2e-08
   EF-hand_6  1 elreaFklfDkdgdGkidaeElrk 24
                +lr+ F+++Dkd++G+i +eE+ +
  EEA18930.1 43 RLRKRFMKLDKDNSGTIEREEFLS 66
                6899******************86 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 9.5e-05
   EF-hand_6   8 lfDkdgdGkidaeElrkalr 27 
                 +fD dg G +d++E+++ l+
  EEA18930.1  82 IFDEDGGGDVDFQEFVSGLS 101
                 79**************9998 PP

  == domain 3  score: 21.4 bits;  conditional E-value: 6.6e-08
   EF-hand_6   2 lreaFklfDkdgdGkidaeElrkalrk 28 
                 l+ aFk +D d+dG+i+  El  +l++
  EEA18930.1 113 LHFAFKVYDIDRDGYISNGELFIVLKM 139
                 7789*********************96 PP

  == domain 4  score: 17.8 bits;  conditional E-value: 9.6e-07
   EF-hand_6   9 fDkdgdGkidaeElrkalr 27 
                  Dkd+dGki++eE++++  
  EEA18930.1 161 ADKDHDGKISFEEFKNMVE 179
                 6**************9875 PP

>> EF-hand_5  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.1   0.0   3.3e-08   7.3e-05       1      23 [.      44      66 ..      44      68 .. 0.89
   2 !    5.0   0.4    0.0081        18       7      21 ..      82      96 ..      79     101 .. 0.88
   3 !   14.2   0.0     1e-05     0.022       4      21 ..     116     133 ..     114     140 .. 0.89
   4 !   28.8   0.3   2.5e-10   5.6e-07       2      25 .]     155     178 ..     153     178 .. 0.88

  Alignments for each domain:
  == domain 1  score: 22.1 bits;  conditional E-value: 3.3e-08
                HHHHHHHH-SS-SSCE-HHHHHH CS
   EF-hand_5  1 lkdtFqaiDlNgDGkIskeELkt 23
                l++ F ++D++++G+I +eE+  
  EEA18930.1 44 LRKRFMKLDKDNSGTIEREEFLS 66
                5777*****************75 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.0081
                HH-SS-SSCE-HHHH CS
   EF-hand_5  7 aiDlNgDGkIskeEL 21
                 +D +g G ++++E+
  EEA18930.1 82 IFDEDGGGDVDFQEF 96
                59************9 PP

  == domain 3  score: 14.2 bits;  conditional E-value: 1e-05
                 HHHHH-SS-SSCE-HHHH CS
   EF-hand_5   4 tFqaiDlNgDGkIskeEL 21 
                 +F+  D ++DG+Is  EL
  EEA18930.1 116 AFKVYDIDRDGYISNGEL 133
                 4*************9887 PP

  == domain 4  score: 28.8 bits;  conditional E-value: 2.5e-10
                 HHHHHHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5   2 kdtFqaiDlNgDGkIskeELktlv 25 
                 ++t  ++D+++DGkIs+eE+k++v
  EEA18930.1 155 DKTIMEADKDHDGKISFEEFKNMV 178
                 349999***************986 PP

>> EF-hand_8  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       1.5   3.3e+03      25      39 ..      24      38 ..      19      41 .. 0.79
   2 !   11.0   0.0   0.00013       0.3      32      51 ..      48      67 ..      47      69 .. 0.92
   3 !    7.5   0.5    0.0016       3.6      31      50 ..      79      98 ..      79     102 .. 0.89
   4 !   19.7   1.2   2.5e-07   0.00057       2      48 ..      88     133 ..      87     140 .. 0.85
   5 !   22.1   0.5   4.4e-08   9.8e-05      32      54 ..     158     180 ..     135     181 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.5
   EF-hand_8 25 eeevdilfrefDtdg 39
                 + +d+++++  +d+
  EEA18930.1 24 SQVLDSIISASNFDR 38
                567899999998887 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 0.00013
   EF-hand_8 32 frefDtdgdGkisfeEFcvl 51
                f+++D d++G+i  eEF+ l
  EEA18930.1 48 FMKLDKDNSGTIEREEFLSL 67
                889**************975 PP

  == domain 3  score: 7.5 bits;  conditional E-value: 0.0016
   EF-hand_8 31 lfrefDtdgdGkisfeEFcv 50
                ++  fD+dg G ++f EF+ 
  EEA18930.1 79 MIAIFDEDGGGDVDFQEFVS 98
                7778**************86 PP

  == domain 4  score: 19.7 bits;  conditional E-value: 2.5e-07
   EF-hand_8   2 kgkItreelrrilrilglkk...glseee.vdilfrefDtdgdGkisfeEF 48 
                 +g ++++e+++     gl     + +++e ++  f+  D+d+dG+is  E 
  EEA18930.1  88 GGDVDFQEFVS-----GLSAfssKGNKDEkLHFAFKVYDIDRDGYISNGEL 133
                 799********.....87778886888888****************96665 PP

  == domain 5  score: 22.1 bits;  conditional E-value: 4.4e-08
   EF-hand_8  32 frefDtdgdGkisfeEFcvller 54 
                 ++e+D d+dGkisfeEF +++e+
  EEA18930.1 158 IMEADKDHDGKISFEEFKNMVEN 180
                 7899****************986 PP

>> SPARC_Ca_bdg  Secreted protein acidic and rich in cysteine Ca binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.9   0.0    0.0017       3.8      50     111 ..      38      97 ..      12      99 .. 0.88
   2 !   17.9   0.1   1.3e-06    0.0028      53     111 ..     110     175 ..     102     177 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0017
  SPARC_Ca_bdg  50 keckepvawkFsklDtnsdkvlsksELaplraplvklehCikpflescDadkdkkislkEwc 111
                   +e ++ ++ +F klD+++ ++++++E  +l +  v+ +    +++   D d  ++++ +E++
    EEA18930.1  38 REEVDRLRKRFMKLDKDNSGTIEREEFLSLPQ--VSSNPLAPRMIAIFDEDGGGDVDFQEFV 97 
                   5556778889*****************99999..9999999999999999999999999997 PP

  == domain 2  score: 17.9 bits;  conditional E-value: 1.3e-06
  SPARC_Ca_bdg  53 kepvawkFsklDtnsdkvlsksELaplrapl.......vklehCikpflescDadkdkkislkEwc 111
                    e++++ F+  D ++d+++s+ EL  + + +       v+l++ +++ ++++D d+d+kis +E+ 
    EEA18930.1 110 DEKLHFAFKVYDIDRDGYISNGELFIVLKMMvgsnlkdVQLQQIVDKTIMEADKDHDGKISFEEFK 175
                   5789********************97766542333333678999********************96 PP

>> EF-hand_4  Cytoskeletal-regulatory complex EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0     0.034        77      24      66 ..      19      65 ..      10      73 .. 0.71
   2 ?    3.3   0.1     0.034        77      50      66 ..      81      97 ..      68     103 .. 0.80
   3 !    7.9   0.1    0.0013       2.9      41      72 ..     109     140 ..     100     148 .. 0.85
   4 !   12.0   0.5   6.9e-05      0.15      35      66 ..     140     175 ..     137     190 .. 0.77

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.034
   EF-hand_4 24 nkltgdkv.apvlknsklee...dklekiwdladidedgkldfeefc 66
                  + g++v  +++  s+++    d+l k +   d d+ g+++ eef 
  EEA18930.1 19 GSIGGSQVlDSIISASNFDReevDRLRKRFMKLDKDNSGTIEREEFL 65
                556666662468888888761125566667778999999*****996 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.034
   EF-hand_4 50 dladidedgkldfeefc 66
                 + d d  g++df+ef+
  EEA18930.1 81 AIFDEDGGGDVDFQEFV 97
                556778889*******8 PP

  == domain 3  score: 7.9 bits;  conditional E-value: 0.0013
   EF-hand_4  41 eedklekiwdladidedgkldfeefciamrli 72 
                 +++kl+  +++ did dg +   e+ i+++++
  EEA18930.1 109 KDEKLHFAFKVYDIDRDGYISNGELFIVLKMM 140
                 67899999*****************9999986 PP

  == domain 4  score: 12.0 bits;  conditional E-value: 6.9e-05
   EF-hand_4  35 lknskleedklekiwdl....adidedgkldfeefc 66 
                 +  s+l++ +l++i d     ad d+dgk+ feef 
  EEA18930.1 140 MVGSNLKDVQLQQIVDKtimeADKDHDGKISFEEFK 175
                 556888888888887642333899***********6 PP

>> EF-hand_9  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0       1.3   2.8e+03      34      59 ..      40      65 ..      16      67 .. 0.65
   2 ?    0.6   0.0      0.33   7.3e+02       6      37 ..      82     113 ..      78     115 .. 0.80
   3 ?   10.0   0.1   0.00037      0.84       3      62 ..     116     178 ..     114     181 .. 0.83

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 1.3
   EF-hand_9 34 es.eLeelakelDPdgedasvdldtfl 59
                e+ +L +   +lD d+  ++++ + fl
  EEA18930.1 40 EVdRLRKRFMKLDKDNS-GTIEREEFL 65
                44555555566777777.777777775 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.33
   EF-hand_9   6 vcDtqktGrVpvsrlidyLravtaqdpeeseL 37 
                 ++D +  G V  ++ ++ L a  ++  ++ +L
  EEA18930.1  82 IFDEDGGGDVDFQEFVSGLSAFSSKGNKDEKL 113
                 78999999999999999888888887777766 PP

  == domain 3  score: 10.0 bits;  conditional E-value: 0.00037
   EF-hand_9   3 vFevcDtqktGrVpvsrlidyLravtaqdpeeseLeelak....elDPdgedasvdldtflrvm 62 
                  F+v+D+++ G +   +l  +L+ + + + ++++L++       e+D d+  +++ ++ f+ ++
  EEA18930.1 116 AFKVYDIDRDGYISNGELFIVLKMMVGSNLKDVQLQQIVDktimEADKDHD-GKISFEEFKNMV 178
                 59**********************9999*****998875422227887777.999999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (192 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       708  (0.0394891); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1254.41
//
Query:       EEA18931.1  [L=397]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.6e-62  211.2   0.3    2.2e-62  210.8   0.3    1.2  1  Glyco_hydro_cc  Glycosyl hydrolase catalytic core
    0.00036   20.7   6.6     0.0005   20.2   6.6    1.4  1  DUF4667         Domain of unknown function (DUF4667)
  ------ inclusion threshold ------
      0.016   15.5   3.3      0.026   14.8   3.3    1.3  1  DUF4050         Protein of unknown function (DUF4050)
      0.024   13.5   4.8      0.031   13.2   4.8    1.2  1  Apt1            Golgi-body localisation protein domain
      0.042   13.8   3.8       0.05   13.5   3.8    1.2  1  SPX             SPX domain
       0.33   10.8   7.8       0.65    9.8   7.8    1.4  1  CCDC24          Coiled-coil domain-containing protein 24 fami
       0.35   10.1   4.3       0.47    9.7   4.3    1.1  1  BUD22           BUD22
       0.87    9.6  20.5        1.5    8.8  20.5    1.3  1  DUF4614         Domain of unknown function (DUF4614)
       0.92   10.1  25.9        3.2    8.4  25.9    1.9  1  Secretin_N_2    Secretin N-terminal domain
          1    7.4  26.1        1.3    7.0  26.1    1.1  1  AF-4            AF-4 proto-oncoprotein
        2.3    6.4  17.6        2.8    6.1  17.6    1.1  1  RAP1            Rhoptry-associated protein 1 (RAP-1)
        4.1    7.2   8.1          7    6.4   8.1    1.4  1  DUF1635         Protein of unknown function (DUF1635)
        4.6    5.7  12.3          6    5.3  12.3    1.1  1  Macoilin        Macoilin family


Domain annotation for each model (and alignments):
>> Glyco_hydro_cc  Glycosyl hydrolase catalytic core
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  210.8   0.3   1.6e-65   2.2e-62       1     239 []      40     272 ..      40     272 .. 0.95

  Alignments for each domain:
  == domain 1  score: 210.8 bits;  conditional E-value: 1.6e-65
  Glyco_hydro_cc   1 GlaynadasddkllsaksskisWyYnwsskpsselssaalefvPmlwgaksad.tdalanvksaakenskylLgFNePDlksqsnmspeeAaklw 94 
                     G+ayn d s ++ l  +ss isW+Ynw+s ++++l+s  +e+vPmlwg++s   + ++++v++a + +s+y++gFNePDl+sq+++s+++Aa+++
      EEA18931.1  40 GAAYN-DISLVSALCGESSGISWAYNWGSSSDGNLPSG-VEYVPMLWGTGSLYvDGWTSKVEAAIAGGSTYIMGFNEPDLPSQADLSVSDAAAHY 132
                     78998.999999999********************997.7***********999***************************************** PP

  Glyco_hydro_cc  95 kqliqplre.kgvklvsPavaatns.eegleWldeFleacskdckvdflavHwYkgdfeelkehieelheayn....kpiWvTEfalqs.esgda 182
                     kq+++p  + + +klvsPav++ +s ++gl+W+++F+++cs dc v++lavHwY+++++el+++i+++ ++++    +++W+TE+al+s   g +
      EEA18931.1 133 KQYLTP--YvGRAKLVSPAVTSSSSaGQGLSWFESFISECS-DCGVSVLAVHWYGNSVSELQSFITQAISTASnhgiSEVWLTEWALSSdAGGIS 224
                     ******..88**********66666999*************.************777************9999999***********99677788 PP

  Glyco_hydro_cc 183 sqeetkeflnevlawldsqeyVeryawfgfrsevsnvgannaLldenGeltelgsaY 239
                     + ++ ++f++e+ awld+q+  +ry++f         +an +Ll+ nG ++++g+aY
      EEA18931.1 225 DLSTAAAFIQEAGAWLDEQSALTRYSYFY--------VANGYLLS-NGVVNSVGAAY 272
                     8999*************************........999****9.8*******999 PP

>> DUF4667  Domain of unknown function (DUF4667)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   6.6   3.7e-07    0.0005     165     208 ..     261     318 ..     124     346 .. 0.64

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 3.7e-07
     DUF4667 165 a..............slpslssassssssssssssqssssesssdeessnasssstpn 208
                 +              + +s +s+ssssssssssss+ssss+sss++   +++s+st+ 
  EEA18931.1 261 SngvvnsvgaayasaASSSTTSSSSSSSSSSSSSSSSSSSSSSSSSSTTSTTSTSTSI 318
                 0555555444444432222222222222222222222222222222222222223333 PP

>> DUF4050  Protein of unknown function (DUF4050)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.8   3.3   1.9e-05     0.026      72     147 ..     276     351 ..     232     353 .. 0.66

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 1.9e-05
     DUF4050  72 esasseesssssealeeqsaessssssasatattspasseeseeeesvetlvPvappllppsnpirasItpasYps 147
                 +s+s+++sssss++++++s++ssssss+s+++tts++s ++s    +      va p+++++n + ++ + ++Y +
  EEA18931.1 276 ASSSTTSSSSSSSSSSSSSSSSSSSSSSSSSSTTSTTSTSTSIYVAPPTATAAVASPIIDTNNNVASETPTDAYAA 351
                 22223333333333333444444444444444444444444555556666789**************999999975 PP

>> Apt1  Golgi-body localisation protein domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   4.8   2.2e-05     0.031     333     370 ..     278     314 ..     214     359 .. 0.61

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 2.2e-05
        Apt1 333 sssssassssssssrssslelrlkptsstssssssess 370
                 ss++s+ssssssss+sss++++ +++ss+ss++s++s+
  EEA18931.1 278 SSTTSSSSSSSSSSSSSSSSSS-SSSSSSSSTTSTTST 314
                 1111111111111111111111.000111111111111 PP

>> SPX  SPX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   3.8   3.6e-05      0.05     115     160 ..     277     318 ..     194     372 .. 0.65

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 3.6e-05
         SPX 115 ssppsansssssddssesnpadssssssssesesssssspsllrrl 160
                 ss++ ++sssss++ss+s+    sssssss+s+ss++s++s+  ++
  EEA18931.1 277 SSSTTSSSSSSSSSSSSSS----SSSSSSSSSSSSTTSTTSTSTSI 318
                 1111111111111111111....22222333333333333333333 PP

>> CCDC24  Coiled-coil domain-containing protein 24 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   7.8   0.00047      0.65      97     136 ..     255     311 ..     226     320 .. 0.45

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00047
      CCDC24  97 l.................daaaersareespssrPesasskstaasaasgsssasal 136
                 +                 ++aa+ s + +s+ss+ +s+ss+s  +s++s+sss +++
  EEA18931.1 255 AngyllsngvvnsvgaayASAASSSTTSSSSSSSSSSSSSSSSSSSSSSSSSSTTST 311
                 055555666555555443223333333333333333333322122222222222222 PP

>> BUD22  BUD22
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   4.3   0.00034      0.47     236     272 ..     279     314 ..     224     331 .. 0.57

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00034
       BUD22 236 etdeesseesdssdssesasesesessekkkkkkkkk 272
                 +t+++ss++s+ss+ss+s s+s+s+ss++ ++ ++++
  EEA18931.1 279 STTSSSSSSSSSSSSSSSSSSSSSSSSSS-TTSTTST 314
                 12222222222222222222222222222.2222222 PP

>> DUF4614  Domain of unknown function (DUF4614)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8  20.5    0.0011       1.5       8      95 ..     277     364 ..     270     382 .. 0.43

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0011
     DUF4614   8 essssssesessssssessssrslssssesslssksssstdsksssqssestkkrsktktrttvketavqTsdpalayqwtk...aagvaa 95 
                 +ss++ss+s+ssssss+ssss+s+ssss+ss++s+ s+st+ +  + +++       +   +t +++a+ T  +a+a   t+   aa +a+
  EEA18931.1 277 SSSTTSSSSSSSSSSSSSSSSSSSSSSSSSSTTSTTSTSTSIYVAPPTATAA---VASPIIDTNNNVASETPTDAYAAATTAaptAAPTAV 364
                 3333333333333333333333333333344333334444443333333322...222344555566666665555555444222344444 PP

>> Secretin_N_2  Secretin N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4  25.9    0.0023       3.2      16      63 ..     270     316 ..     264     324 .. 0.46

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0023
  Secretin_N_2  16 lsntsvtsGsvsssgsssssssssssssgsssssssssnsssgtkiet 63 
                      +s  s+s++ss+sssssssssssss+sssssssss+  s+t+++t
    EEA18931.1 270 AAYASAASSSTTSSSSSSSSSSSSSSSSSSSSSSSSSST-TSTTSTST 316
                   555555666666666666665555533222222221111.13333322 PP

>> AF-4  AF-4 proto-oncoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0  26.1   0.00097       1.3     462     513 ..     272     325 ..     261     380 .. 0.64

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.00097
        AF-4 462 vesahsssaeSeSsSeSeSSSeSDSe.sEssssdseanepprtatpe.peppat 513
                  +sa sss+ S+SsS S SSS S S  s ssss s++  ++ t+t+    pp++
  EEA18931.1 272 YASAASSSTTSSSSSSSSSSSSSSSSsSSSSSSSSSTTSTTSTSTSIyVAPPTA 325
                 577888888777777766666655551444444444444445554432555554 PP

>> RAP1  Rhoptry-associated protein 1 (RAP-1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1  17.6     0.002       2.8     140     184 ..     273     318 ..     187     348 .. 0.65

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.002
        RAP1 140 eslksssdskskasaksn.vksaskyGesssseesatdsskasasv 184
                  s +sss ++s++s+ s+ + s+s    ssss  s+t ++++s+s+
  EEA18931.1 273 ASAASSSTTSSSSSSSSSsSSSSSSSSSSSSSSSSTTSTTSTSTSI 318
                 2333333333333322220222223333333333333333333332 PP

>> DUF1635  Protein of unknown function (DUF1635)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   8.1    0.0051         7      77     113 ..     278     311 ..     245     340 .. 0.51

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0051
     DUF1635  77 aslsgassiederrasnnsfsssdleesivssevidp 113
                 +s++ +ss+ +   +s++s sss +++s +ss++++ 
  EEA18931.1 278 SSTTSSSSSSSS--SSSSSSSSS-SSSSSSSSSTTST 311
                 222222222211..111111111.1111111111111 PP

>> Macoilin  Macoilin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3  12.3    0.0044         6     316     353 ..     276     313 ..     251     357 .. 0.53

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0044
    Macoilin 316 vkskssssssssnknskkasagsagssnssskkhsess 353
                 ++s+++ssssss+++s+++s++s++ss+sss + s++s
  EEA18931.1 276 ASSSTTSSSSSSSSSSSSSSSSSSSSSSSSSSTTSTTS 313
                 11111111111111111111111111111111111111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1646  (0.0918066); expected 358.6 (0.02)
Passed bias filter:                      697  (0.0388756); expected 358.6 (0.02)
Passed Vit filter:                       197  (0.0109878); expected 17.9 (0.001)
Passed Fwd filter:                        41  (0.0022868); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.81u 0.33s 00:00:01.14 Elapsed: 00:00:00.48
# Mc/sec: 2501.66
//
Query:       EEA18932.1  [L=588]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.1e-10   39.6   0.3    4.8e-10   38.9   0.3    1.3  1  Fungal_trans  Fungal specific transcription factor domain
    5.5e-10   39.2   8.0    1.1e-09   38.2   8.0    1.5  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
       0.18   11.9   0.0       0.44   10.7   0.0    1.6  1  Phage_Cox     Regulatory phage protein cox


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.9   0.3   8.1e-14   4.8e-10      69     265 ..     170     366 ..     125     368 .. 0.80

  Alignments for each domain:
  == domain 1  score: 38.9 bits;  conditional E-value: 8.1e-14
  Fungal_trans  69 fiafplraeili.....hedfsspssslwilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaF 160
                   +i++++++++ +        ++ ++++  ++qs l++++ ++++++++ +   ++ a +la ++g+ r+++ +++  +   ++  +e++rR+ww+ +
    EEA18932.1 170 HIYSFQQWDMELknhleACFCEASPTDPVMVQSRLIYSIALFWYDYKTEAASQIEAATQLAIDMGMFRREFASEH--GAGDPIL-EECWRRTWWMLY 263
                   34455555544444443334677777799*******************************************995..5667777.************ PP

  Fungal_trans 161 ylDktialklGrpp.llddsqinlpLPcddddlwesddaseetlvetklsneeksrkiasfllaLkkilskiagsllsiekqlqqrdlqseklswve 256
                   +++ ++a  lG  +    + + ++ LPc + ++++      +tl+e  ++++e+  + ++++++++ +++ +   +l+ + + ++  ++ ++l  ++
    EEA18932.1 264 VVEAFYAGTLGTKTfKAMNMEATVDLPCQELEYESGKIPIPKTLQE--FDCREFATDETTQFSSFAYLIGAVRCAVLAMSTTPKLPAKE-DSLHIMQ 357
                   **************54556667777******999999999999999..9**********************988899999999999999.99***** PP

  Fungal_trans 257 eleraldnW 265
                   ++++ald W
    EEA18932.1 358 TTDSALDGW 366
                   ******999 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.2   8.0   1.9e-13   1.1e-09       2      38 ..      15      50 ..      14      52 .. 0.95

  Alignments for each domain:
  == domain 1  score: 38.2 bits;  conditional E-value: 1.9e-13
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfysessk 38
                aC +Cr +++KCd++kP+C  C + +++C  y++s++
  EEA18932.1 15 ACLPCRVRHIKCDGNKPSCNGCNEAGKQCD-YTRSRR 50
                9*****************************.999986 PP

>> Phage_Cox  Regulatory phage protein cox
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   7.4e-05      0.44      13      39 ..     322     348 ..     311     366 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 7.4e-05
                 EHHHHHHHHT--HHHHHHHHHHT-S-E CS
   Phage_Cox  13 teekFAeliGKtekAvrkmikdgKLPv 39 
                     FA liG  + Av +m +  KLP+
  EEA18932.1 322 QFSSFAYLIGAVRCAVLAMSTTPKLPA 348
                 4578**********************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (588 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       429  (0.0239277); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.43
# Mc/sec: 4066.96
//
Query:       EEA18933.1  [L=319]
Description: zinc-containing alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.2e-17   65.2   0.0    2.3e-17   64.3   0.0    1.5  1  ADH_zinc_N_2    Zinc-binding dehydrogenase
    2.3e-11   43.8   0.0    5.1e-10   39.4   0.0    2.3  2  ADH_zinc_N      Zinc-binding dehydrogenase
    1.4e-06   28.2   0.0    3.9e-06   26.7   0.0    1.8  1  ADH_N           Alcohol dehydrogenase GroES-like domain
     0.0028   17.8   0.0     0.0068   16.5   0.0    1.6  2  DapB_N          Dihydrodipicolinate reductase, N-terminus
  ------ inclusion threshold ------
      0.072   13.0   0.2       0.13   12.2   0.2    1.4  1  NAD_binding_10  NAD(P)H-binding
      0.093   12.2   0.1       0.17   11.4   0.1    1.4  1  adh_short       short chain dehydrogenase
        0.1   11.9   0.4        0.2   10.9   0.4    1.4  1  AlaDh_PNT_C     Alanine dehydrogenase/PNT, C-terminal domain
       0.11   11.6   0.0       0.15   11.1   0.0    1.2  1  RmlD_sub_bind   RmlD substrate binding domain
       0.11   12.3   0.6       0.19   11.6   0.1    1.6  2  KR              KR domain
       0.12   11.9   0.2       0.17   11.3   0.2    1.3  1  Epimerase       NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.3   0.0   1.3e-20   2.3e-17       1     133 []     186     315 ..     186     315 .. 0.86

  Alignments for each domain:
  == domain 1  score: 64.3 bits;  conditional E-value: 1.3e-20
                   TT-SEEEETTSTTHHHHH-TT-EEEEEES-HHHHH.HHHHHHE.EEEEEEEE----...S-EEE-CHHHCTTT-EEEE--GGG...-.-HHHHHHHH CS
  ADH_zinc_N_2   1 lGAdevidyrtedfeaatggegvDvvldtvggealleaslkvl.pggGrlvsiggpp..lsaallkpakkrkgrsvkyeflfsmkasaqadileela 94 
                   lGA+ev+dy t+ +e++   ++v +vldtvgg+ l +++++ + +  G++v++g+pp  ++++  + a+  k ++ +y+ ++ ++++  ++ l +  
    EEA18933.1 186 LGAHEVLDYNTPGWETQ--LQNVALVLDTVGGDIL-TKTWETIdESDGTIVTVGDPPpsWAFGKCQAAESTKWPNAQYTYFV-VSPN-AER-LSKAS 276
                   8*************855..578***********99.*******9777*******7777966666666666666888887777.9999.777.***** PP

                   HHHHHHH----EEEEEEGGGHHHHHHHHHSS--SSEEEE CS
  ADH_zinc_N_2  95 alieeGklrpvvdrvfpleeaaeAhrylesgrarGKiVl 133
                    +i++G+++p   ++fp++ea +A+   +++    K+V+
    EEA18933.1 277 GMIDAGAITPLEVKSFPFHEAEKAWSCARQRGRGHKVVI 315
                   *************************99998887777775 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.4   0.0   2.8e-13   5.1e-10       1      89 [.     155     236 ..     155     244 .. 0.88
   2 ?    2.1   0.0       0.1   1.8e+02      18      67 ..     263     319 .]     247     319 .] 0.60

  Alignments for each domain:
  == domain 1  score: 39.4 bits;  conditional E-value: 2.8e-13
                 HHHHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTESEEEETTTC.HHHHHHHHHTTTSSEEEEEESSCSHHHHHHHHHCEEEE.EEEEECS CS
  ADH_zinc_N   1 gvGlaavqlAkalGaeviavdsseeklelakklGadevinykea.dlverikeltggegvdvvfecvGsgatleaalkllkpg.GrlvvvG 89 
                 +vG +avq+A   Ga via +s ++    +k+lGa+ev++y ++  ++ +++      +v +v+++vG g+ l+   + +++  G++v+vG
  EEA18933.1 155 AVGRLAVQIASSHGAYVIALASARH-HSTLKELGAHEVLDY-NTpGWETQLQ------NVALVLDTVG-GDILTKTWETIDESdGTIVTVG 236
                 69*****************888888.5**************.5445555555......677*******.***********9988******9 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.1
                 EEEESSHHHHHHHHHTTESEEEET........TTCHHHHHHHHHT.TTSSEEEEEESSC CS
  ADH_zinc_N  18 iavdsseeklelakklGadeviny........keadlverikelt.ggegvdvvfecvG 67 
                 ++v++++e+l +a  +    +i++        +e   ++++  +  +g+g +vv+++vG
  EEA18933.1 263 FVVSPNAERLSKASGMIDAGAITPlevksfpfHE--AEKAWSCARqRGRGHKVVIDFVG 319
                 5677788877777775333344443444333222..33333333335999******998 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.7   0.0   2.2e-09   3.9e-06       2      67 ..      29      91 ..      28     118 .. 0.82

  Alignments for each domain:
  == domain 1  score: 26.7 bits;  conditional E-value: 2.2e-09
                TEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS.--TT-EEEE-SEEE- CS
       ADH_N  2 gevlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkk.lkvGdrVvveplisc 67
                 e+l++v aagi g ++   +    l +++  i+GH+i+G+++++gpe  + +++G++V++  + s 
  EEA18933.1 29 SEILVRVYAAGITGDEVLWHE----LYNSPTRIPGHDISGVISAFGPEYAGpFRIGQEVLAFLAASS 91
                69***********98874443....567778899***************999*******98666554 PP

>> DapB_N  Dihydrodipicolinate reductase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   3.8e-06    0.0068       1      58 [.     145     202 ..     145     218 .. 0.86
   2 ?   -3.1   0.0       4.5     8e+03      63      74 ..     302     317 ..     263     317 .. 0.50

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 3.8e-06
                 EEEEEETTTSHHHHHHHHHHHHSTTEEEEEEEETTCSTTTTTBHHHHSSSS--S-BEB CS
      DapB_N   1 ikvavvGasGrmGkevvkaveeaedlelvaavdrkeselegkdagellglgklgvavt 58 
                 ++v+v+GasG +G+  v+ ++++  + ++ a  r++s+l++  a e+l+ ++ g +++
  EEA18933.1 145 MRVLVTGASGAVGRLAVQIASSHGAYVIALASARHHSTLKELGAHEVLDYNTPGWETQ 202
                 89*********************************99999999999999888777765 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 4.5
                 HHHHH....-SEEEE- CS
      DapB_N  63 evlek....advliDF 74 
                 +++++      v+iDF
  EEA18933.1 302 SCARQrgrgHKVVIDF 317
                 3333333334588887 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.2   7.2e-05      0.13       1      40 [.     151     191 ..     151     215 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 7.2e-05
                     TTTSHHHHHHHHHHHHC-T-EEEEE..ETTHHHCHHHHCTTT CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtal..vRnpeklaeleaeeg 40 
                     GA+G vGrl+v+ + ++g   v al  +R+ + l+el a+e 
      EEA18933.1 151 GASGAVGRLAVQIASSHG-AYVIALasARHHSTLKELGAHEV 191
                     9****************6.67777634688888888877654 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1   9.2e-05      0.17       3      47 ..     147     189 ..     145     213 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 9.2e-05
                 EEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT CS
   adh_short   3 vlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee 47 
                 vlvtGas+ +Gr  ++   + Ga v+++++   + + ++kel+++
  EEA18933.1 147 VLVTGASGAVGRLAVQIASSHGAYVIALASA--RHHSTLKELGAH 189
                 9************************997665..445677887765 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.4   0.00011       0.2      21      99 ..     138     213 ..     134     216 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00011
                  CEETCB---EEEEEST.SHHHHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTTCECEEHCHHHHHHHHHHHH-SEEEE-- CS
  AlaDh_PNT_C  21 GgvpgvepakvlviGg.GvaGlqAiatakglgakVtvlDvrparleqleslgakfvevlksqeellaeavkeadvvigtv 99 
                  Ggv+  +  +vlv G+ G +G  A+++a++ ga V +l   ++    l++lga+  evl  +    + +++++ +v  tv
   EEA18933.1 138 GGVK-EAGMRVLVTGAsGAVGRLAVQIASSHGAYVIALAS-ARHHSTLKELGAH--EVLDYNTPGWETQLQNVALVLDTV 213
                  5666.44569*****88******************99964.5567788889999..888888888888888888877665 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   8.6e-05      0.15       1      35 [.     145     179 ..     145     204 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 8.6e-05
                    EEEEEESTTSHHHHHHHHHCTTTSEEEEEE-TTT- CS
  RmlD_sub_bind   1 mkilvtGanGqlGseLakqlaeeglevlaltreel 35 
                    m++lvtGa+G++G+  ++ ++++g+ v+al +++ 
     EEA18933.1 145 MRVLVTGASGAVGRLAVQIASSHGAYVIALASARH 179
                    89***************************966533 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.1       4.3   7.7e+03     138     150 ..      88     100 ..      84     106 .. 0.78
   2 ?   11.6   0.1   0.00011      0.19       3      37 ..     147     181 ..     146     231 .. 0.86

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 4.3
                 HHHH--TT-HHHH CS
          KR 138 agllgsagqanYa 150
                 a+  g +gqa+Y 
  EEA18933.1  88 AASSGGQGQADYV 100
                 6778999999996 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 0.00011
                 EEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..- CS
          KR   3 ylitGGlGgLGlelarwlaekgarhlvllsRsaaa 37 
                 +l+tG+ G++G+  ++   ++ga  ++l s ++++
  EEA18933.1 147 VLVTGASGAVGRLAVQIASSHGAYVIALASARHHS 181
                 69****************************99543 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.2   9.7e-05      0.17       1      40 [.     147     186 ..     147     221 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 9.7e-05
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHC CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrlssasntarl 40 
                 +lVtGa+G +G+  v+   ++g  vi+l++ ++ s  ++l
  EEA18933.1 147 VLVTGASGAVGRLAVQIASSHGAYVIALASARHHSTLKEL 186
                 79********************99***9999766665554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (319 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      314  (0.0175135); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2204.52
//
Query:       EEA18934.1  [L=379]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.076   13.1   0.0       0.42   10.7   0.0    2.0  2  Leucyl-specific  Leucine-tRNA synthetase-specific domain


Domain annotation for each model (and alignments):
>> Leucyl-specific  Leucine-tRNA synthetase-specific domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.0      0.11     2e+03      14      28 ..     250     264 ..     241     274 .. 0.72
   2 ?   10.7   0.0   2.3e-05      0.42      19      43 ..     318     342 ..     311     345 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.11
  Leucyl-specific  14 vrLseeaRirLelee 28 
                        L+e+ R  L+l  
       EEA18934.1 250 GNLNEASRLLLDLSA 264
                      459999999999864 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 2.3e-05
  Leucyl-specific  19 eaRirLeleeseLsleevkKmGAEL 43 
                       +R  L+l+ + Ls + ++KmG E+
       EEA18934.1 318 HRRQSLQLPPTMLSADSMEKMGQEI 342
                      6999******************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (379 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       852  (0.0475208); expected 358.6 (0.02)
Passed bias filter:                      424  (0.0236488); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 2634.23
//
Query:       EEA18935.1  [L=320]
Description: 37S ribosomal protein S9 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.7e-40  136.9   0.2    8.8e-40  136.0   0.2    1.5  1  Ribosomal_S9  Ribosomal protein S9/S16


Domain annotation for each model (and alignments):
>> Ribosomal_S9  Ribosomal protein S9/S16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  136.0   0.2   4.9e-44   8.8e-40       1     121 []     200     320 .]     200     320 .] 0.99

  Alignments for each domain:
  == domain 1  score: 136.0 bits;  conditional E-value: 4.9e-44
                   EECTTEEEEEEEEESSSEEEETTEECCHHSTTSCHHHHHCHHHHHTTTSSSEEEEEEEESS-HHHHHHHHHHHHHHHHHHHHHHHHHHHCTCCCTS- CS
  Ribosomal_S9   1 GrrKesvArvwikegkgkilvngksleeYfkeeaarekvleplkltgllgkfdvfvkvkgGGlsgqaeAirlgiaraLvalekeekkeLkkaglltr 97 
                   G+rKes+A v+++eg+g++lvn+k++ + f++ ++re++l +l++t+ l+k++v +kv+gGG++gqaeAi+l++araL+ +e++ k++L++ag++t 
    EEA18935.1 200 GKRKESSAVVYLVEGEGEVLVNDKNIVDAFPRVHDRESALWALRCTHRLDKYNVWAKVSGGGVTGQAEAITLAVARALMVHEPALKPVLRQAGVITV 296
                   8**********************************************************************************88************ PP

                   B--------TTSSCTTB----S-- CS
  Ribosomal_S9  98 DpRvvErkKtgkkkARkkyqwskR 121
                   D+R+vErkK+g+ kARk ++w+kR
    EEA18935.1 297 DARRVERKKPGHVKARKMPTWVKR 320
                   ***********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (320 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       612  (0.0341346); expected 358.6 (0.02)
Passed bias filter:                      518  (0.0288917); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2311.14
//
Query:       EEA18936.1  [L=406]
Description: translation elongation factor eEF-1 subunit gamma, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-44  150.0   0.1    3.9e-44  149.1   0.1    1.5  1  EF1G      Elongation factor 1 gamma, conserved domain
    1.1e-14   54.4   0.0    3.1e-14   53.0   0.0    1.9  1  GST_C     Glutathione S-transferase, C-terminal domain
    1.2e-09   38.4   0.0    3.7e-09   36.8   0.0    1.9  2  GST_N     Glutathione S-transferase, N-terminal domain
    9.2e-07   28.8   0.4    2.8e-06   27.3   0.1    2.0  2  GST_C_2   Glutathione S-transferase, C-terminal domain
     0.0003   21.1   0.0     0.0008   19.8   0.0    1.6  1  GST_N_3   Glutathione S-transferase, N-terminal domain
     0.0013   18.9   0.0     0.0028   17.8   0.0    1.6  1  GST_C_3   Glutathione S-transferase, C-terminal domain


Domain annotation for each model (and alignments):
>> EF1G  Elongation factor 1 gamma, conserved domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  149.1   0.1   1.3e-47   3.9e-44       1     107 []     244     350 ..     244     350 .. 0.99

  Alignments for each domain:
  == domain 1  score: 149.1 bits;  conditional E-value: 1.3e-47
        EF1G   1 kakdplaalpkskfvldewKrkYsnedteekalkyfwenfdkeeyslwkveYkyneeltktfmssnliggffqrleklrkyaFgsvvvfgennnseisG 99 
                 kak+pl+al k ++ ldewKr+Ysn+dt+++a+++fw+n+++eeyslw v+Ykyn+el+ tfm++nliggff rle++rk  Fg ++v+gen ++ i+G
  EEA18936.1 244 KAKHPLEALGKPTLILDEWKRQYSNNDTRPVAMPWFWQNYKPEEYSLWLVDYKYNDELKLTFMANNLIGGFFARLEASRKFLFGAASVYGENYKCLIRG 342
                 89************************************************************************************************* PP

        EF1G 100 vwlfrGqe 107
                 ++l+rGqe
  EEA18936.1 343 AFLVRGQE 350
                 ******97 PP

>> GST_C  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.0   0.0     1e-17   3.1e-14      18      92 ..     117     192 ..      64     193 .. 0.87

  Alignments for each domain:
  == domain 1  score: 53.0 bits;  conditional E-value: 1e-17
                 HHHHHHHHHHHHHHHHHHHHHHHHHHTSSSSSTTSSCHHHHHHHHHHHHHHHHTTTTT.TTTSHHHHHHHHHHHTS CS
       GST_C  18 ekkeelvdealekvaevlsaleeelkkqdylvGdkltlADialvpilnwlqrlglafg.qekfpnlkawlerimar 92 
                   ++++vde+ ++ a++l++le++l  +++lvG+++tlADi  + i+++ + ++l+ + + +f ++++w+++++++
  EEA18936.1 117 PYNKKTVDEQATASAAALKVLETHLTANTFLVGERITLADIFTAGIIRRGFATVLDKKfRSEFVAVTRWFNTVVNQ 192
                 345669******************************************999999999999************9986 PP

>> GST_N  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.8   0.0   1.2e-12   3.7e-09       3      75 ..       4      71 ..       2      72 .. 0.94
   2 ?   -3.4   0.0       4.4   1.3e+04      28      41 ..     364     377 ..     363     389 .. 0.68

  Alignments for each domain:
  == domain 1  score: 36.8 bits;  conditional E-value: 1.2e-12
                EEEESSSTSHTHHHHHHHHHHTT-EEEEEEECSTTTCGGCHHHHHHCTTS-SSEEEET.TEEEESHHHHHHHHH CS
       GST_N  3 ltlysirgsprahrirlllaakgveyevvpldfeageekspellklnplgkvPaLedn.gkkltESraIleYia 75
                ++ly+  g+ r+    ++++a g++ evv+  ++++ +      ++nplgkvPa+++  g+kltE++aI+ Yi 
  EEA18936.1  4 GKLYGSTGHGRTIPSVVAAKANGLDLEVVETAPGKAST------DINPLGKVPAFVGAnGFKLTEAMAIAIYIT 71
                6899999999*999*******************99985......9************99*************96 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 4.4
                 EEEEEECSTTTCGG CS
       GST_N  28 yevvpldfeageek 41 
                 ye+++ld ++ e++
  EEA18936.1 364 YEFKKLDHTKEEDR 377
                 88888886555443 PP

>> GST_C_2  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.1   9.3e-10   2.8e-06       4      67 ..     123     186 ..     120     188 .. 0.88
   2 ?   -3.0   0.0       2.6   7.8e+03      21      31 ..     317     328 ..     316     329 .. 0.80

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 9.3e-10
                 HCHHHHHCCHCHHHCTTT---SS.CTTCS--HHHHHHHHHHHHHHHHHHS----TT-HHHHHHH CS
     GST_C_2   4 veraleqldaaldaleahLadspflfGdqptlaDialapflvrlraagpgfdireaypnlraWl 67 
                 v+++ ++  aal++le+hL+  +fl G+++tlaDi+ a+ + r  a   +  +r+++  + +W+
  EEA18936.1 123 VDEQATASAAALKVLETHLTANTFLVGERITLADIFTAGIIRRGFATVLDKKFRSEFVAVTRWF 186
                 788889999*********************************8877766788888888888886 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 2.6
                 T---SS..CTTC CS
     GST_C_2  21 hLadsp.flfGd 31 
                 +L+ s+ flfG+
  EEA18936.1 317 RLEASRkFLFGA 328
                 7888889***96 PP

>> GST_N_3  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.0   2.7e-07    0.0008      16      72 ..      21      75 ..      19      78 .. 0.89

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 2.7e-07
                HHHHHT--EEEE---TTTTHHHHHHH-TT--SSEEE.TTS-EEESHHHHHHHHHHHH- CS
     GST_N_3 16 aLnekglpvevvevtpgehdeellaknplgkvPvLe.ddgealtdSlaIidyLeelyp 72
                a +  gl+ evve+ pg+       +nplgkvP+++  +g +lt+  aI+ y+ ++ +
  EEA18936.1 21 AAKANGLDLEVVETAPGKA---STDINPLGKVPAFVgANGFKLTEAMAIAIYITSQNE 75
                678899************7...568**********9778*************988765 PP

>> GST_C_3  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   9.5e-07    0.0028      23      67 ..     124     166 ..     100     194 .. 0.74

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 9.5e-07
                 HHHHHHHHCHHHHHHHHHHCHGTSSSSTTS--HHHHHHHHHHHHH CS
     GST_C_3  23 efleerlpkflkyfekvlkkkgggylvgdklTyADlalfqvldgl 67 
                 +   +     lk++e++l+  ++++lvg+++T+AD++   ++   
  EEA18936.1 124 DEQATASAAALKVLETHLT--ANTFLVGERITLADIFTAGIIRRG 166
                 555566677899*******..99*************988877654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (406 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       630  (0.0351386); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.55u 0.25s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 2803.92
//
Query:       EEA18937.1  [L=629]
Description: NIF domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.1e-24   86.1   5.4    2.5e-24   85.8   2.2    2.6  2  NIF        NLI interacting factor-like phosphatase
  ------ inclusion threshold ------
      0.011   15.2   0.0      0.022   14.3   0.0    1.4  1  DUF705     Protein of unknown function (DUF705)
      0.029   14.7   0.8        0.1   12.9   0.2    2.3  2  HAD_SAK_2  HAD domain in Swiss Army Knife RNA repair proteins


Domain annotation for each model (and alignments):
>> NIF  NLI interacting factor-like phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.1      0.53   3.2e+03      26      49 ..     113     136 ..      97     143 .. 0.70
   2 !   85.8   2.2   4.2e-28   2.5e-24       2     155 ..     321     518 ..     320     519 .. 0.75

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 0.53
         NIF  26 gekvevsvlkRpgldefLkelskl 49 
                  ++v +  ++R +ld + k++  +
  EEA18937.1 113 STQVSYAKQRRNHLDALRKKMRDY 136
                 455777788888888888888655 PP

  == domain 2  score: 85.8 bits;  conditional E-value: 4.2e-28
         NIF   2 tLVLDLDetLvhsklekskklkvegekvevsvlkRpgldefLkelsklyevvifTasseeyaeavidil..dpekkllshrlyrescv...kk.kg..e 92 
                 +++LDL++tL+++k           + +++ +++Rp ld+fL++l +   v+++++s +++++a++d++    +k++l +r++r++      + ++  +
  EEA18937.1 321 LVILDLNGTLLYRK----------RKAFPPKFIRRPALDYFLERLTSRHMVMVWSSSRRDTVDAICDEIfsTVQKQKLVARWSRDHLDltpEQfNNkvQ 409
                 79************..........7899*****************************************98677777**********644422222445 PP

         NIF  93 yvKdLsl.........................l................gr..dlsrvvivDdspdsfelqpengipiksffs..dkkDneLlk.llpl 145
                 ++K L++                         l                ++  d+s++v++Dds+ +++++p+n+i++++f++  +k+D++ lk ll  
  EEA18937.1 410 VYKVLEKvwadkniqakfptkksragkaafnsLryapgldeqtemtgfmNKrwDQSNTVLIDDSTLKAAANPYNIIQVPEFTNvpNKNDQTVLKeLLLK 508
                 55555553333333334444444444444444044444455444454453369****************************877788887766548888 PP

         NIF 146 lkelakvddv 155
                 ++ lak++dv
  EEA18937.1 509 IRVLAKSNDV 518
                 8888899888 PP

>> DUF705  Protein of unknown function (DUF705)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   3.6e-06     0.022     127     185 ..     312     374 ..     298     383 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 3.6e-06
      DUF705 127 lslylkikhvvvfDlDstLitdeeev....elRdhavydsLdelkerhvlvLWsYGnaehvae 185
                 l l +  + +v++Dl+ tL+  + ++     +R +a+  +L++l  rh++++Ws   ++ v  
  EEA18937.1 312 LDLHFMQPLLVILDLNGTLLYRKRKAfppkFIRRPALDYFLERLTSRHMVMVWSSSRRDTVDA 374
                 5667777889**********88765422227***********************999998865 PP

>> HAD_SAK_2  HAD domain in Swiss Army Knife RNA repair proteins
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       1.7     1e+04      89      99 ..     215     229 ..     188     252 .. 0.62
   2 ?   12.9   0.2   1.8e-05       0.1       2     113 ..     322     472 ..     321     488 .. 0.72

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 1.7
   HAD_SAK_2  89 k....sRaqeilewl 99 
                       R++ i+ew 
  EEA18937.1 215 RlmllVREAHIKEWR 229
                 134445555555553 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 1.8e-05
   HAD_SAK_2   2 iFLDiDGVLnpekskkrregeedealdpe.averlkriveatgakiVlsstWrrred...eelkallkaag.....rpriigvtpdlpeeeseeekk.. 89 
                 ++LD+ G L   k+k+ +++     +  + a++ + + +++ ++  V+ss+ r ++d   +e+ +  +++      +   ++ tp+   ++ ++ k   
  EEA18937.1 322 VILDLNGTLLYRKRKAFPPK-----FIRRpALDYFLERLTSRHMVMVWSSSRRDTVDaicDEIFSTVQKQKlvarwSRDHLDLTPEQFNNKVQVYKVle 415
                 89************999885.....5554499999988999999*************777333222222223333466667777777776665554488 PP

   HAD_SAK_2  90 .................................sRaqeilewlrrheeveawvalDD 113
                                                  + + e++ +++++++ ++ v +DD
  EEA18937.1 416 kvwadkniqakfptkksragkaafnslryapglDEQTEMTGFMNKRWDQSNTVLIDD 472
                 888888888888888888888888888888888888888888888888888888888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (629 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       952  (0.0530983); expected 358.6 (0.02)
Passed bias filter:                      460  (0.0256568); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.27s 00:00:00.89 Elapsed: 00:00:00.42
# Mc/sec: 4473.61
//
Query:       EEA18938.1  [L=357]
Description: pre-rRNA processing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-49  167.6  32.5    2.3e-49  167.6  32.5    2.9  2  RRP36     rRNA biogenesis protein RRP36
  ------ inclusion threshold ------
      0.015   15.0   2.6      0.031   13.9   2.6    1.6  1  DUF2229   CoA enzyme activase uncharacterised domain (DUF2229


Domain annotation for each model (and alignments):
>> RRP36  rRNA biogenesis protein RRP36
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?  -10.2  14.8         2   1.8e+04      80     159 ..      27     114 ..       4     165 .. 0.53
   2 !  167.6  32.5   2.6e-53   2.3e-49       1     166 []     175     346 ..     175     346 .. 0.97

  Alignments for each domain:
  == domain 1  score: -10.2 bits;  conditional E-value: 2
       RRP36  80 eelkrelqrlesrekerekkererevlkelkkeekekvkegkk.......pfflkksekkklllkekfeelk..kkkklekaierkrkK 159
                 e l  e++  e+  ++++++e+e++  +  ++ee +  ++ +        +  ++ ++ +++  + +f +++     k ++ i +krk+
  EEA18938.1  27 ELLSDEMEGSEEDGRSNSDEEQEDSNSDAAESEEDDDQDDEQDgdedlsdAQSIQSANDREA-IQSEFRQISfgALAKAQNSIGKKRKR 114
                 33333333334444444444444444444444443333322222112332333333333333.33445555432223555566666666 PP

  == domain 2  score: 167.6 bits;  conditional E-value: 2.6e-53
       RRP36   1 rkskhaPtevsskkpvsrkrevvkvkkkksrDPRFdsls......geldedlfeknYaFLdeyrekEleelkkelkkekdkeeekeelkrelqrlesre 93 
                 r+skhaP+++ssk++vsrkr++++ +  ksrDPRFd+++       + +++ +e++Y+FLdeyr++E+++lk++l k+kd + +keelkr+++++++r+
  EEA18938.1 175 RSSKHAPAVQSSKVAVSRKRTIIEPTTVKSRDPRFDPTVvkssssVRRNNSSAENAYSFLDEYRASEIKQLKEQLSKTKD-ATQKEELKRAITSATDRQ 272
                 89********************98789999********999987658899******************************.****************** PP

       RRP36  94 kerekkererevlkelkkeekekvkegkk..pfflkksekkklllkekfeelkkkkklekaierkrkKnasKekk 166
                 ++ ++++rerevl+e+kk+ek+++kegkk  p+flkkse+k+++lk+k+e++ ++k++ ka+er+rkK+asKekk
  EEA18938.1 273 RALDNRKREREVLQEHKKKEKQLIKEGKKsqPYFLKKSELKREVLKKKYESM-GSKERAKALERRRKKVASKEKK 346
                 ****************************************************.*********************8 PP

>> DUF2229  CoA enzyme activase uncharacterised domain (DUF2229)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   2.6   3.4e-06     0.031      97     176 ..     215     294 ..     199     341 .. 0.67

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 3.4e-06
     DUF2229  97 qglpeviknnleeeikllspvldledkke...lakqlleel.giskkeikkAvekAleaqkafkeelrkkgeelleeleeegkk 176
                  + + v +nn   + ++   +ld  +++e   l++ql ++    +k+e+k+A+ +A ++q+a +++  k+++e+l+e ++++k+
  EEA18938.1 215 KSSSSVRRNNS--SAENAYSFLDEYRASEikqLKEQLSKTKdATQKEELKRAITSATDRQRALDNR--KREREVLQEHKKKEKQ 294
                 33333333333..333333444443333222366666643347999*****************988..6667899986665544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (357 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2679  (0.149423); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        97  (0.00541023); expected 17.9 (0.001)
Passed Fwd filter:                        28  (0.00156172); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.97u 0.36s 00:00:01.33 Elapsed: 00:00:00.58
# Mc/sec: 1862.56
//
Query:       EEA18939.1  [L=1142]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      5e-10   39.4   0.5    9.7e-10   38.5   0.5    1.5  1  DUF659         Protein of unknown function (DUF 659)
    5.2e-06   26.2   0.4    2.2e-05   24.1   0.1    2.2  2  Dimer_Tnp_hAT  hAT family C-terminal dimerisation region
  ------ inclusion threshold ------
       0.15   11.6   0.1       0.26   10.8   0.1    1.3  1  DUF2110        Uncharacterized protein conserved in archaea (
       0.38   11.3   6.2        1.2    9.7   6.2    1.8  1  APG6_N         Apg6 coiled-coil region


Domain annotation for each model (and alignments):
>> DUF659  Protein of unknown function (DUF 659)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.5   0.5   2.2e-13   9.7e-10       1     144 [.      53     205 ..      53     218 .. 0.82

  Alignments for each domain:
  == domain 1  score: 38.5 bits;  conditional E-value: 2.2e-13
      DUF659   1 PsseeLrgtlLqeeveeikkkvkeikkswektgcsillDgwtdkkgrslinflvscpkGtvFlksvdassekktaeylaelldkvieevgaen...... 93 
                 P+++++ g+lL e ++e   ++k+i    + ++++i++D+++++++++++ +++++p+++      d+++e+ +a+++ e l + +e++ a+       
  EEA18939.1  53 PDRHRIGGSLLTELYTES--YTKTIGIWRQIQHLNITVDETSNINHQRVMVITITTPQRSWLYCLKDMENERLNAKNITEWLLHQLEALLATLfdgdid 149
                 89999*********9998..4554444445577**************************9999999***********9999999999855544444455 PP

      DUF659  94 ...Vvqvitdnasnykkagklleekyp..tifwtpcaahclnlmledilklkwvke 144
                    + +  td+ s ++ +++ l++k p  + f++pc +h+l+l+++d+l +k  + 
  EEA18939.1 150 wkcINSLSTDTCSTMRLVWEILQRKSPlqHAFMIPCDSHGLQLIFKDLLDMKVSQA 205
                 555********************8765328*******************9765443 PP

>> Dimer_Tnp_hAT  hAT family C-terminal dimerisation region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.1     5e-09   2.2e-05      11      83 ..     426     493 ..     408     495 .. 0.91
   2 ?   -2.3   0.0      0.85   3.8e+03      31      64 ..     596     629 ..     593     634 .. 0.81

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 5e-09
                    ---TT....--HHHHHHHTTTTSHHHHHHHHHHHTS-S-TTTTHHHHHHTHHHHH-TTT---HHHHHHHHHHH CS
  Dimer_Tnp_hAT  11 vlrrkeksefdvlewwkensskyPnlsklardvLsipvssaasErsFstlgkvllesrnsleplnveallcie 83 
                    ++     +e +++ +w e  +  P l  +a ++    + s+++Er+Fs +   +++ rn+l  + ve+ll+++
     EEA18939.1 426 CW-----EESEITIFWLEAADIAPKLASFANRLIHTVANSVTAERAFSLMNLQHTKIRNRLSVEQVEKLLFLQ 493
                    33.....4689************************************************************97 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 0.85
                    TTSHHHHHHHHHHHTS-S-TTTTHHHHHHTHHHH CS
  Dimer_Tnp_hAT  31 skyPnlsklardvLsipvssaasErsFstlgkvl 64 
                    + yP +  +   +L+   +s+ +E s s   + +
     EEA18939.1 596 TTYPETLGAHLFLLTFLWTSVHAEQSGSFTRRLI 629
                    678888888888999999*****99988776666 PP

>> DUF2110  Uncharacterized protein conserved in archaea (DUF2110)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.1   5.9e-05      0.26      95     168 ..      57     130 ..      54     140 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 5.9e-05
     DUF2110  95 ripkdelkpLgegspeqiaerFGlvqhlpleveveeveeeekeiearltdeqvdrlyewkkgkedrlivnsatr 168
                 ri  + l++L++ s ++ +  +  +qhl ++v+ +++ ++++ +  ++t  q+  ly +k ++++rl++ ++t 
  EEA18939.1  57 RIGGSLLTELYTESYTKTIGIWRQIQHLNITVDETSNINHQRVMVITITTPQRSWLYCLKDMENERLNAKNITE 130
                 566778999************************9998888899999************************9996 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   6.2   0.00027       1.2      66     125 ..     485     544 ..     470     550 .. 0.92

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00027
      APG6_N  66 lleeLkelekereeleaelaaleeelealeeeeerfwreynelqlelleleeeldsleaq 125
                  +e+L  l+ ++ +l+++l++    +++le+ee++  r y+e++le ++  + l+s++ +
  EEA18939.1 485 QVEKLLFLQINEYQLQEKLNEEPTPEQQLEDEEAESARVYREQSLEFSSILNNLNSMDQK 544
                 6789999************************************************99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1142 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       638  (0.0355848); expected 358.6 (0.02)
Passed bias filter:                      381  (0.0212505); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.78u 0.31s 00:00:01.09 Elapsed: 00:00:00.48
# Mc/sec: 7133.42
//
Query:       EEA18940.1  [L=135]
Description: DNA-directed RNA polymerase I and III 14 KDA polypeptide [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.1e-33  114.8   0.0    1.5e-33  114.4   0.0    1.2  1  RNA_pol_L_2  RNA polymerase Rpb3/Rpb11 dimerisation domain
    1.4e-14   53.3   0.0    1.9e-14   52.8   0.0    1.2  1  RNA_pol_L    RNA polymerase Rpb3/Rpb11 dimerisation domain
  ------ inclusion threshold ------
      0.062   11.8   0.0      0.065   11.7   0.0    1.1  1  DUF859       Siphovirus protein of unknown function (DUF859)


Domain annotation for each model (and alignments):
>> RNA_pol_L_2  RNA polymerase Rpb3/Rpb11 dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.4   0.0   2.5e-37   1.5e-33       2      74 ..      44     116 ..      43     117 .. 0.97

  Alignments for each domain:
  == domain 1  score: 114.4 bits;  conditional E-value: 2.5e-37
                  EEEEEES--HHHHHHHHHHHTTSTTEEEEEEECSSTTTSEEEEEEEESTSS-HHHHHHHHHHHHHHHHHHHHH CS
  RNA_pol_L_2   2 ltfeingEDhTLgnlLrhlllknpsVefagYkipHPlepkmnlriqtkssnnpleaLkkalkdlldicdelee 74 
                  ++f++++E hTLgn+Lr++++knp+Vef+gY+ipHP+e kmnlriqt+++++++eaL+k+l+dl+d+cd +++
   EEA18940.1  44 ASFQFKEEGHTLGNALRYVIMKNPKVEFCGYTIPHPSEAKMNLRIQTYDDTTAIEALEKGLNDLMDLCDVVSD 116
                  79*******************************************************************9986 PP

>> RNA_pol_L  RNA polymerase Rpb3/Rpb11 dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.8   0.0   3.2e-18   1.9e-14       1      69 []      45     111 ..      45     111 .. 0.95

  Alignments for each domain:
  == domain 1  score: 52.8 bits;  conditional E-value: 3.2e-18
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   RNA_pol_L   1 efllrgvdhtlgNaLRrillsevpgvaiea...pvvkvntdkdklilevetdgslkPeealkeAlkiLkekl 69 
                 +f++++++htlgNaLR++++ ++p+v++++   p       + k++l+++t   +++ eal+++l++L++ +
  EEA18940.1  45 SFQFKEEGHTLGNALRYVIM-KNPKVEFCGytiPH----PSEAKMNLRIQTYDDTTAIEALEKGLNDLMDLC 111
                 69******************.*********98866....7799**************************987 PP

>> DUF859  Siphovirus protein of unknown function (DUF859)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   1.1e-05     0.065     155     216 ..      43     105 ..      11     121 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 1.1e-05
      DUF859 155 tvrykfgnksgkiasnvttsvswtipldland.iPnstsgtgtiyvdtydggkligtqsktlt 216
                    ++f ++  ++++     +   ++++++ + iP  ++  +++ ++tyd+++ i+  +k l+
  EEA18940.1  43 AASFQFKEEGHTLGNALRYVIMKNPKVEFCGYtIPHPSEAKMNLRIQTYDDTTAIEALEKGLN 105
                 457899999999999999999999******7549*********************98777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (135 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       356  (0.0198561); expected 358.6 (0.02)
Passed bias filter:                      303  (0.0169); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.39u 0.28s 00:00:00.67 Elapsed: 00:00:00.42
# Mc/sec: 962.05
//
Query:       EEA18941.1  [L=100]
Description: DNA-directed RNA polymerase I and III 14 KDA polypeptide [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.8e-25   87.1   0.0      7e-25   86.6   0.0    1.2  1  RNA_pol_L_2  RNA polymerase Rpb3/Rpb11 dimerisation domain
    6.1e-10   38.4   0.0    8.4e-10   38.0   0.0    1.2  1  RNA_pol_L    RNA polymerase Rpb3/Rpb11 dimerisation domain


Domain annotation for each model (and alignments):
>> RNA_pol_L_2  RNA polymerase Rpb3/Rpb11 dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.6   0.0   7.8e-29     7e-25       2      50 ..      44      92 ..      43      98 .. 0.94

  Alignments for each domain:
  == domain 1  score: 86.6 bits;  conditional E-value: 7.8e-29
                 EEEEEES--HHHHHHHHHHHTTSTTEEEEEEECSSTTTSEEEEEEEEST CS
  RNA_pol_L_2  2 ltfeingEDhTLgnlLrhlllknpsVefagYkipHPlepkmnlriqtks 50
                 ++f++++E hTLgn+Lr++++knp+Vef+gY+ipHP+e kmnlriqt++
   EEA18941.1 44 ASFQFKEEGHTLGNALRYVIMKNPKVEFCGYTIPHPSEAKMNLRIQTYG 92
                 79*********************************************96 PP

>> RNA_pol_L  RNA polymerase Rpb3/Rpb11 dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.0   0.0   9.3e-14   8.4e-10       1      50 [.      45      92 ..      45      99 .. 0.89

  Alignments for each domain:
  == domain 1  score: 38.0 bits;  conditional E-value: 9.3e-14
                xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxx RF
   RNA_pol_L  1 efllrgvdhtlgNaLRrillsevpgvaiea...pvvkvntdkdklilevetdg 50
                +f++++++htlgNaLR++++ ++p+v++++   p       + k++l+++t g
  EEA18941.1 45 SFQFKEEGHTLGNALRYVIM-KNPKVEFCGytiPH----PSEAKMNLRIQTYG 92
                69******************.*********98865....77999******877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (100 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       380  (0.0211947); expected 358.6 (0.02)
Passed bias filter:                      341  (0.0190195); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.34u 0.25s 00:00:00.59 Elapsed: 00:00:00.39
# Mc/sec: 769.82
//
Query:       EEA18942.1  [L=123]
Description: NADH-ubiquinone oxidoreductase B14 subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.5e-05   25.6   0.6    2.1e-05   25.2   0.6    1.2  1  Complex1_LYR_2   Complex1_LYR-like
    0.00021   21.3   0.4    0.00045   20.2   0.4    1.6  1  Complex1_LYR     Complex 1 protein (LYR family)
  ------ inclusion threshold ------
      0.033   14.0   0.0      0.039   13.7   0.0    1.1  1  RRM_Rrp7         Rrp7 RRM-like N-terminal domain
       0.11   12.6   0.0       0.58   10.2   0.0    2.0  2  IKKbetaNEMObind  I-kappa-kinase-beta NEMO binding domain


Domain annotation for each model (and alignments):
>> Complex1_LYR_2  Complex1_LYR-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   0.6   4.6e-09   2.1e-05       1      69 [.      25     104 ..      25     114 .. 0.84

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 4.6e-09
  Complex1_LYR_2   1 vlsLYrrllrelrelppelr......slgdayvraefrrhk..........hlk.npeeialflknqreYaellerynpglkmtee 69 
                     v++ Yr++lr+ + ++++++      s++++++r++f++h+           l   + e+++ l+ +++  + ++++       ee
      EEA18942.1  25 VRKSYREWLRASP-EIQTMYslnlpvSAIRTKIRQQFEQHRyvsqinvvdvLLYkSHSEFQETLNYWKQLSHVMKYF-----RAEE 104
                     7899********9.556666777889*************999*******99555478899**************999.....3333 PP

>> Complex1_LYR  Complex 1 protein (LYR family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.4     1e-07   0.00045       2      52 ..      24      78 ..      23      85 .. 0.80

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 1e-07
  Complex1_LYR  2 qvLsLYRalLRearkfpdyn....treyfrrriRdeFrknkhvtDpekieellkk 52
                  +v + YR +LR++  ++       +   +r +iR++F++++ v+ +  +  ll k
    EEA18942.1 24 RVRKSYREWLRASPEIQTMYslnlPVSAIRTKIRQQFEQHRYVSQINVVDVLLYK 78
                  67777******885555544577999999***************99999888755 PP

>> RRM_Rrp7  Rrp7 RRM-like N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   8.7e-06     0.039      41     114 ..      39     113 ..      26     120 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 8.7e-06
    RRM_Rrp7  41 srslFlvNlPiettletlkkffqkvalgatiesvvsslltdeqe.dvsidltkltsdlelkdeekdeeeaklPkn 114
                  ++++ +NlP+ +   ++++ f+++   ++i+ v   l +   e ++ ++  k  s +++  + ++e +a+lP n
  EEA18942.1  39 IQTMYSLNLPVSAIRTKIRQQFEQHRYVSQINVVDVLLYKSHSEfQETLNYWKQLSHVMKYFRAEEEPAARLPPN 113
                 579999*************************98865555544441567899999999999899999999999977 PP

>> IKKbetaNEMObind  I-kappa-kinase-beta NEMO binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0       0.3   1.4e+03       6      15 ..      61      70 ..      60      72 .. 0.85
   2 ?   10.2   0.0   0.00013      0.58       5      24 ..      84     103 ..      83     106 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.3
  IKKbetaNEMObind  6 EnqnyLsqLt 15
                     E ++y sq +
       EEA18942.1 61 EQHRYVSQIN 70
                     889****975 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.00013
  IKKbetaNEMObind   5 eEnqnyLsqLtslmqettke 24 
                      +E++ny +qL+++m+ ++ e
       EEA18942.1  84 QETLNYWKQLSHVMKYFRAE 103
                      8*************977666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (123 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       818  (0.0456244); expected 358.6 (0.02)
Passed bias filter:                      505  (0.0281667); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.39u 0.26s 00:00:00.65 Elapsed: 00:00:00.40
# Mc/sec: 911.97
//
Query:       EEA18943.1  [L=184]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (184 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2811  (0.156785); expected 358.6 (0.02)
Passed bias filter:                      595  (0.0331865); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.52u 0.31s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 1250.88
//
Query:       EEA18944.1  [L=465]
Description: hydrolase, alpha/beta fold family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.9e-10   39.5   0.1    1.1e-09   38.3   0.1    1.6  1  Abhydrolase_1  alpha/beta hydrolase fold
    5.3e-05   22.6   0.0    0.00018   20.9   0.0    1.8  1  Hydrolase_4    Serine aminopeptidase, S33


Domain annotation for each model (and alignments):
>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.3   0.1   1.2e-13   1.1e-09       1     233 [.     150     373 ..     150     396 .. 0.78

  Alignments for each domain:
  == domain 1  score: 38.3 bits;  conditional E-value: 1.2e-13
                    SEEEEE-STTT.CGGGGTTGHHHHHHHHT..TSEEEEEEETTSTTSSSTTTGB.CHHSHHHHHHHHHHHHHHCTTSSEEEEEETHHHHHHHHHHHH CS
  Abhydrolase_1   1 pvlvilhGlpg.ssdvwaerglapaLakd..gfdvillDlrGvgySspapacinddygtasvaddldrildalgddkltlvGhSmGGmialayaae 93 
                    p lv lhGl+g s++v+ +++lap   ++  g++ ++++ rG+++ + +     +   t++v+ ++++++  +++++l  +G+S+G  i  +y+ e
     EEA18944.1 150 PMLVALHGLTGgSHEVYLRAALAPLVLDEtaGWEACVVNGRGCAQMKLSTPLLFNARATWDVRQVIKWLRKTFPNRPLFGIGFSLGANILVNYLGE 245
                    56999******6666699999**999999***************9766666555788*************************************** PP

                    H.GGGEEEEEEESECSSCCHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHHHHCCSCHHHHHHHHHHHHHHHCHHHCCHHHHHHHCHHHHHHHHHH CS
  Abhydrolase_1  94 y.perVkalvllgaidpaaslieaqrqqaksfpdffdgyaadcarnpagplladelaaleqrhrlvdalkfpdkskrfpssgsdnasslatgalks 188
                       +   + + ++a    + ++ +  ++a +  +    ++ +    ++  l++ ++  l+ + rl       d+ +  + +++d+a+ +a ++  +
     EEA18944.1 246 EgENCLLNAAVICA----NPWNLDVTNIALRSTWLGAEVYSAHMAVSLVNLFNQHVDELTHHPRLNV----DDMKDVKYIHEFDRAVQCALWG--Y 331
                    *7555566666666....4677777777777777777777777777777777777777666666544....7888888888888888888887..7 PP

                    HHHHHHCCHHHHHHHHHCTHHHHSEEEEEEETTCSSSCHHHHHHH CS
  Abhydrolase_1 189 ieqwpttdsaklllrlrelknvlaptlvisgtsDplvppkaledl 233
                      + +++  a++ ++l     + +p l i +++Dp+   +a+ + 
     EEA18944.1 332 PTEGAYHRDASSTDSLLA---IRIPFLAINAEDDPISVKQAIPYD 373
                    777777777777777665...777999999999999988777655 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.0     2e-08   0.00018      60     206 ..     209     366 ..     203     378 .. 0.51

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 2e-08
  Hydrolase_4  60 dDlaafvekvkeehpelplfllGhSmGGliallyllrypd..kva.glilsaPalkikakl.........kappllklllkllgkllpklqv.snnlk 144
                   D++++++ ++++ p++plf +G S+G+ i ++yl ++ +   ++ ++i+++P+    +++         +          + +  +    v   n  
   EEA18944.1 209 WDVRQVIKWLRKTFPNRPLFGIGFSLGANILVNYLGEEGEncLLNaAVICANPWNLDVTNIalrstwlgaE----------VYSAHMAVSLVnLFNQH 296
                  59*********************************666553456635555555533333332222222221..........22221111111322333 PP

  Hydrolase_4 145 adslsrdpe.vvaayeadplv.hgkitvrlllelldam......krleeraakitlPllllhGeaDkvvd 206
                   d l+++p+ +v+ +++ +++  ++  v+ +l  + +       ++ +++  +i++P+l + +e+D++  
   EEA18944.1 297 VDELTHHPRlNVDDMKDVKYIhEFDRAVQCALWGYPTEgayhrdASSTDSLLAIRIPFLAINAEDDPISV 366
                  3333333332334444444443333333333222222200000022233333455777777777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (465 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       324  (0.0180713); expected 358.6 (0.02)
Passed bias filter:                      318  (0.0177366); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.31s 00:00:00.83 Elapsed: 00:00:00.46
# Mc/sec: 3062.84
//
Query:       EEA18945.1  [L=395]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (395 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       571  (0.0318478); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.41
# Mc/sec: 2893.87
//
Query:       EEA18946.1  [L=111]
Description: hypothetical protein PMAA_012170 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (111 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       626  (0.0349155); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.25s 00:00:00.67 Elapsed: 00:00:00.42
# Mc/sec: 788.07
//
Query:       EEA18947.1  [L=149]
Description: hypothetical protein PMAA_012180 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
     0.0094   15.7   7.3      0.013   15.2   7.3    1.4  1  MNHE            Na+/H+ ion antiporter subunit
  ------ inclusion threshold ------
      0.013   15.6   0.8      0.033   14.3   0.8    1.7  1  Cas_Cas2CT1978  CRISPR-associated protein (Cas_Cas2CT1978)
       0.19   11.9   0.1       0.41   10.8   0.1    1.6  1  ARL6IP6         Haemopoietic lineage transmembrane helix


Domain annotation for each model (and alignments):
>> MNHE  Na+/H+ ion antiporter subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   7.3   2.3e-06     0.013       8     111 ..       4     108 ..       1     141 [. 0.83

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 2.3e-06
        MNHE   8 Wllltgs..lgelllGlllallvalllrrlllplrrvllrllayllvflweivkanldVakrvlrpklpirpgiv.kvplrlksdlaltllansitltP 103
                 W +   +  ++++ +G+l+ ++v +++  ++  + +++ r++++++v ++ +v a ++ a+  l+ + ++++g+v kv + ++sdla ++ a    +  
  EEA18947.1   4 WSASCFDavAEKVEAGVLVEAVVFFAV--YFDAVEPPVNRVAVVVAVAVVVVVAAEFALARAELQAEVKVESGVVeKVAVSVESDLAEVMAAVGAAIYV 100
                 444444467778889999999999999..34555556888888888999999*************999*******55****************999999 PP

        MNHE 104 GTltvdvd 111
                 G++ + v 
  EEA18947.1 101 GSVAAAVA 108
                 99998875 PP

>> Cas_Cas2CT1978  CRISPR-associated protein (Cas_Cas2CT1978)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.8   5.4e-06     0.033       5      42 ..      75     112 ..      74     143 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 5.4e-06
                     EEES--HHHHHHHHHHSEEEETTEEEEEE-HHHHHHHH CS
  Cas_Cas2CT1978   5 vleavparlRGeLtrwllEvragVyvgrvsarVreklw 42 
                     v+e+v+ ++  +L+ ++  v a++yvg+v a+V+  ++
      EEA18947.1  75 VVEKVAVSVESDLAEVMAAVGAAIYVGSVAAAVAAAVV 112
                     7899*****************************99875 PP

>> ARL6IP6  Haemopoietic lineage transmembrane helix
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.1   6.9e-05      0.41      28      54 ..      14      40 ..       1      45 [. 0.81

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 6.9e-05
     ARL6IP6 28 spllaGllvaaFsyglvYlDsavPGvs 54
                  + aG+lv a ++  vY+D+++P v+
  EEA18947.1 14 EKVEAGVLVEAVVFFAVYFDAVEPPVN 40
                45679*******************886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (149 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1325  (0.0739026); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.41u 0.25s 00:00:00.65 Elapsed: 00:00:00.40
# Mc/sec: 1110.44
//
Query:       EEA18948.1  [L=697]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   1.9e-165  551.7   7.7   2.4e-165  551.4   7.7    1.0  1  Cohesin_load  Cohesin loading factor
  ------ inclusion threshold ------
        1.7    9.0   9.4         27    5.1   0.1    5.1  5  TPR_12        Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> Cohesin_load  Cohesin loading factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  551.4   7.7  2.7e-169  2.4e-165       2     595 ..      72     683 ..      71     684 .. 0.98

  Alignments for each domain:
  == domain 1  score: 551.4 bits;  conditional E-value: 2.7e-169
  Cohesin_load   2 evvelLlslaeeyltaAhevvskv...kseeeleqYykLiatGikCLeavlkdfklpprqearvtlrLariLleETenideAeeylskailiaeknr 95 
                   e++ lLl la+eyl+aAh+ ++ +   ++e +l++YykL+atG++CL+a+  +f++pp +ea ++lr+ariL+eET+n+ +Ae++lsk+      n+
    EEA18948.1  72 EYQTLLLALADEYLNAAHSKGTVIalsNNELDLKEYYKLVATGLGCLQAAQTNFRMPPLTEALTRLRYARILIEETDNDILAETALSKG------NK 162
                   6789*************************************************************************************......** PP

  Cohesin_load  96 lidlkfvcqfLlarllektnpkaAlksldeliedaetyqhnewvylfrllriqlslqt..dkdnsaalenlqslaelanrkgdkklfvvlslleall 190
                   l+dlk+ +q+Llar+l k+npkaA k +d++ied+ety+h++w y+frllri+l+l++  ++d  +a+ nlq+l +la+r+gdk ++vv++l+ea +
    EEA18948.1 163 LLDLKYTMQQLLARMLHKSNPKAAAKAVDKMIEDVETYKHTPWEYAFRLLRISLALASssHQDFVIAIHNLQKLTNLATRNGDKLVVVVAALIEAVA 259
                   ************************************************************************************************* PP

  Cohesin_load 191 hlrrgspkdvlevlqeiiaaarslqldeeseqipqlkalllllellvslqkddvknvkekLkalqsfldelkdkkswsswsedgsiklkiters... 284
                   hl+++ + d+ e++q++ a ars+qld   ++ipq+  +l+++++ +sl ++d +++++kL+ +qs++d+  +++ w+  ++++  +l+ ++++   
    EEA18948.1 260 HLQQSTSPDSVEQAQHAVAVARSHQLDPRVQEIPQIGSMLQMVDISCSLLEYDLNQASQKLQIMQSMMDQRINDARWRE-DGSFLVPLNTQTPPkpt 355
                   **************************************************************************97777.66666666665555*** PP

  Cohesin_load 285 ...........glklifswLpkkdllaLlYllsglvnlykkktd..ksekflqkalrqleklklksnnessnslstlsekikwlsvikcyvkfylil 368
                               l l ++wLp++dl+aL+Y+ls++++  k+++d  k+ek+lq++lr+++ +  k  +e ++s+  +s++ +w++ ++c+++++l++
    EEA18948.1 356 eigdilrvengKLCLTLHWLPQHDLYALCYFLSSMTLGAKNSHDgrKAEKYLQEGLRMVRGNF-KAPEEVKESVVAASKRLEWRRILYCNILVHLTF 451
                   *********9533899********************************************988.99******************************* PP

  Cohesin_load 369 iafvlknwkkankeleeletasnkleskllkelaplllyLeglyaqskgdlkaAlaqyk..........etaarkskerelyilsllNlviIlesev 455
                    a+++++w+ a + l+el++ s++l+s l ++ ++l+ y +g++aq++gdl aAla y           + ++r++++r+++il+ lN ++Il+++ 
    EEA18948.1 452 LACARTDWESASQSLKELRSSSEELGSALPESISSLMAYATGVIAQGNGDLVAALAAYDspllslssstNRTMRNDPRRDTAILAGLNTILILREPS 548
                   ************************************************************************************************* PP

  Cohesin_load 456 seddkelnkllsqleplcsnspnknislanalllattslfepisineekssllealkaakaikntqllsillnlisaklfegeleeqtkkser.alq 551
                   +++++ l+++l  +ep c  s+nk+i++a++l++at++++++i   ++k++l++al+ a+ i+n+q++++ l+++s+k+f+g+++eq++ks+r +++
    EEA18948.1 549 HPSHSRLEQVLALVEPQCLGSSNKYIQAAYYLVCATVHNESTI---QTKQYLQQALQSATGINNSQITCMTLTFMSWKYFRGVVGEQSEKSARaGRA 642
                   *******************************************...*************************************************** PP

  Cohesin_load 552 lakksidysdglWvlvaetilaqlleqlgerakaeqteesldal 595
                   +akk+    d lWv+v++++la++l+ +g++++a+ ++e++d+l
    EEA18948.1 643 MAKKA---NDRLWVSVTDQMLAETLDRQGKADEARGVREEADRL 683
                   *****...********************************9986 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.1     0.018   1.6e+02      21      76 ..     228     281 ..     211     282 .. 0.88
   2 ?    2.5   0.0      0.02   1.8e+02      39      76 ..     376     415 ..     373     416 .. 0.76
   3 ?   -1.0   0.1      0.24   2.2e+03       6      53 ..     446     492 ..     442     510 .. 0.58
   4 ?   -1.0   0.0      0.25   2.2e+03      24      51 ..     595     620 ..     566     626 .. 0.73
   5 ?    5.1   0.1    0.0031        27      30      65 ..     641     674 ..     630     680 .. 0.76

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.018
      TPR_12  21 eAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                  A+ +l+k  ++a+r   +d++ ++ +    + +++++    + +e  ++a+a+a+
  EEA18948.1 228 IAIHNLQKLTNLATRN--GDKLVVVVAALIEAVAHLQQSTSPDSVEQAQHAVAVAR 281
                 6899999999999887..9999999999999*******9************99998 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.02
      TPR_12  39 pdhpltattlrnLgrlyral..gryeeAlelleealaiae 76 
                 p+h+l+a +++  ++++ a    + ++A+++l+e l++ +
  EEA18948.1 376 PQHDLYALCYFLSSMTLGAKnsHDGRKAEKYLQEGLRMVR 415
                 678888888888888885441466679*********9965 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 0.24
      TPR_12   6 lnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgr 53 
                 l++l  + +++ +++ A + l++ +   ++l G   p+ +++l ++++
  EEA18948.1 446 LVHLTFLACARTDWESASQSLKELRSSSEEL-GSALPESISSLMAYAT 492
                 5555566677777777777777777777655.5666666666655544 PP

  == domain 4  score: -1.0 bits;  conditional E-value: 0.25
      TPR_12  24 ellekaleiarrllGpdhpltattlrnL 51 
                 ++l++al+ a+ +   ++  t+ tl  +
  EEA18948.1 595 QYLQQALQSATGI--NNSQITCMTLTFM 620
                 6788888888777..6666666666655 PP

  == domain 5  score: 5.1 bits;  conditional E-value: 0.0031
      TPR_12  30 leiarrllGpdhpltattlrnLgrlyralgryeeAl 65 
                 +++a+++   d+++++ t + L+++++++g+ +eA+
  EEA18948.1 641 RAMAKKA--NDRLWVSVTDQMLAETLDRQGKADEAR 674
                 5666666..788889999999999999999999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (697 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       681  (0.0379832); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.43
# Mc/sec: 4896.83
//
Query:       EEA18949.1  [L=207]
Description: centromere protein Cse4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      4e-42  143.7   0.2      4e-42  143.7   0.2    2.1  2  Histone        Core histone H2A/H2B/H3/H4
    0.00035   20.6   0.0    0.00075   19.6   0.0    1.5  1  CENP-T_C       Centromere kinetochore component CENP-T histon
     0.0016   18.8   0.1      0.003   17.9   0.1    1.4  1  CENP-S         CENP-S protein
  ------ inclusion threshold ------
       0.06   13.6   0.5       0.14   12.4   0.5    1.6  1  CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) a


Domain annotation for each model (and alignments):
>> Histone  Core histone H2A/H2B/H3/H4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   7.3         2   8.9e+03       8      42 ..      40      62 ..       3      92 .. 0.47
   2 !  143.7   0.2   8.9e-46     4e-42      12     131 .]      76     200 ..      62     200 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 2
                EEXXXXEEXXXXXXXXXXHTTS-SSSSB--TTT-X CS
     Histone  8 arkesektapekkvsakkerkasskskkkkkrryr 42
                ++ +s++t+p+++++a++++            ++ 
  EEA18949.1 40 TTTSSPITSPRSPTTARNTK------------QPM 62
                22222222222222222222............222 PP

  == domain 2  score: 143.7 bits;  conditional E-value: 8.9e-46
                 XXEEXXXXXXXXXXHT..TS-SSSSB--TTT-XTTHHHHHHHHHHHHXXSXXSXHHHHHHHHHHHH......TTSSSXEEXHHHHHHHHHHHHHHHHHH CS
     Histone  12 sektapekkvsakker..kasskskkkkkrryrpgtvalkeirkyqkstdlliqklpfaRvvreivk.....sekedlrisaeavlalqealEallvel 103
                 + +++p  k  ++  +  +    + + k+rry+pgtvalkeirkyq+s dlli klpfaR+vre+       + +++lr+++ a++alqea+Ea+lv+l
  EEA18949.1  76 RVTKRPAGKAPRS--SniQPGDPTPIGKRRRYKPGTVALKEIRKYQRSFDLLISKLPFARLVREVALdllpaEVGAELRWQSHAIMALQEAAEAFLVHL 172
                 2222222222222..245777888999***************************************99******************************* PP

                 HHHHHHHHHHTTXSEEXHHHHHHHHHHT CS
     Histone 104 feeAnllakhaKRvTitpkDiqlArrlr 131
                 fe++nl+a+haKRvTi++kDiqlArr+r
  EEA18949.1 173 FEDTNLCAIHAKRVTIMQKDIQLARRIR 200
                 **************************97 PP

>> CENP-T_C  Centromere kinetochore component CENP-T histone fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.0   1.7e-07   0.00075      11      76 ..     133     198 ..     125     203 .. 0.83

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 1.7e-07
    CENP-T_C  11 avvkklakrfakasg.skaklekealkalekasdkffeqvgeDLeayakHagRKtidesDvilLmkr 76 
                  +v+ +a ++  a+  ++ + + +a+ al++a + f+  + eD +  a Ha+R ti ++D+  L +r
  EEA18949.1 133 RLVREVALDLLPAEVgAELRWQSHAIMALQEAAEAFLVHLFEDTNLCAIHAKRVTIMQKDIQ-LARR 198
                 4688888887766555999999**************************************86.4555 PP

>> CENP-S  CENP-S protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.1   6.6e-07     0.003      26      71 ..     153     198 ..     133     201 .. 0.91

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 6.6e-07
      CENP-S  26 atkqfiaaltelvykqlenlakDLeaFakHAkRstittdDvlLlaR 71 
                   +++i al e   + l +l +D ++ a HAkR ti ++D+ L  R
  EEA18949.1 153 WQSHAIMALQEAAEAFLVHLFEDTNLCAIHAKRVTIMQKDIQLARR 198
                 56789************************************99766 PP

>> CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) and archaeal histone
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.5   3.2e-05      0.14      27      64 ..     159     196 ..     152     196 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 3.2e-05
                    HHHHHHHHHHHHHHHHHHHHHHCCTTSSCE-HHHHHHH CS
  CBFD_NFYB_HMF  27 eliaecveefieelaseAaeickkekrKtikaehiklA 64 
                      ++e++e f+ +l + ++  + ++kr ti++++i+lA
     EEA18949.1 159 MALQEAAEAFLVHLFEDTNLCAIHAKRVTIMQKDIQLA 196
                    679********************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (207 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1002  (0.0558871); expected 358.6 (0.02)
Passed bias filter:                      545  (0.0303977); expected 358.6 (0.02)
Passed Vit filter:                        82  (0.0045736); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.51u 0.30s 00:00:00.81 Elapsed: 00:00:00.44
# Mc/sec: 1425.68
//
Query:       EEA18950.1  [L=232]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.5e-37  126.7   0.1    8.8e-37  126.5   0.1    1.0  1  adh_short     short chain dehydrogenase
    1.8e-27   96.4   0.1    2.5e-27   96.0   0.1    1.0  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
      2e-12   47.4   0.0    2.6e-12   47.0   0.0    1.1  1  KR            KR domain
     0.0017   17.9   0.1      0.016   14.7   0.1    2.0  1  Epimerase     NAD dependent epimerase/dehydratase family
  ------ inclusion threshold ------
       0.17   11.6   0.3       0.66    9.7   0.3    1.9  1  QRPTase_C     Quinolinate phosphoribosyl transferase, C-termi


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  126.5   0.1   2.5e-40   8.8e-37       1     172 [.      52     230 ..      52     232 .] 0.90

  Alignments for each domain:
  == domain 1  score: 126.5 bits;  conditional E-value: 2.5e-40
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHH..HHHHHHHHHHHT....TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---S.S--SS CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvvvdrsee..kleevakelkee....gakalaiqvDvtdreevealvekavkklgkldvLvnNAGi.tgsgp 92 
                 k+vl+tG+s+GIGrai+ ++ak+Ga+ ++++ ++   +l+ +++e  +     + k+l+++v +++re+ve++ ++++ ++g+ d++vnNAGi  g++ 
  EEA18950.1  52 KAVLITGGSRGIGRAIVLAYAKAGASFIAAGARSGtvELASAVEEAAKSsnrpAPKYLPLTVEMSNRESVEEAAADVEREFGRCDIIVNNAGIfGGFQL 150
                 78***************************555443014444444444444455788*************************************999*** PP

                 GGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTE CS
   adh_short  93 fselseeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgi 172
                 ++e++ + w ++++vN+ g++l+tra++p mlk   +  vnvsS  ++  +  ++aY  sK av+ l++ + +e++++gi
  EEA18950.1 151 IEEYDPDMWTNIFDVNVRGPYLITRALIPLMLKTGDAYMVNVSSAGALLTNRTLSAYQISKTAVTRLAEFVNEEYSEKGI 230
                 ******************************************************************************98 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   96.0   0.1   6.9e-31   2.5e-27       3     164 ..      60     230 ..      57     231 .. 0.91

  Alignments for each domain:
  == domain 1  score: 96.0 bits;  conditional E-value: 6.9e-31
                   TTSHHHHHHHHHHHTT-EEEEEESSGGH...HHHHHHHHHHTTSEE.....EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH- CS
  adh_short_C2   3 asgIGraiAkalaeeGaevvltdlneea...kkrveelaeelgaev.....lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpflets 91 
                    +gIGrai+ a+a++Ga+ +++ ++      +++vee+a++ ++ +     l +  +++e+ve+++++v+++fg+ Di+vnnagi     + ++e +
    EEA18950.1  60 SRGIGRAIVLAYAKAGASFIAAGARSGTvelASAVEEAAKSSNRPApkylpLTVEMSNRESVEEAAADVEREFGRCDIIVNNAGIFGG-FQLIEEYD 155
                   59****************999988776544678999999998866445579999*********************************9.999999** PP

                   HHHHHHHHHHHTHHHHHHHHHHHHHCTSC..CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTE CS
  adh_short_C2  92 reefdraldvnlyslfllakaalplmkeg..gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgi 164
                    + + +++dvn+++ +l+++a++plm ++  + +vn+ss ga  +    +ay+++K a+  l+  +  e+ +kgi
    EEA18950.1 156 PDMWTNIFDVNVRGPYLITRALIPLMLKTgdAYMVNVSSAGALLTNRTLSAYQISKTAVTRLAEFVNEEYSEKGI 230
                   ************************665553788***********************************9999998 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.0   0.0   7.2e-16   2.6e-12       3     162 ..      54     220 ..      52     227 .. 0.84

  Alignments for each domain:
  == domain 1  score: 47.0 bits;  conditional E-value: 7.2e-16
                 EEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHH..HHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE------.---TT CS
          KR   3 ylitGGlGgLGlelarwlaekgarhlvllsRsaaadedsk..aliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlr.dklle 98 
                 +litGG  g+G++++   a+ ga+ ++  +Rs++++ +s+  +  ++ ++   +   + ++ s++++ve++ +++++e+++   +++ Ag++   +l+e
  EEA18950.1  54 VLITGGSRGIGRAIVLAYAKAGASFIAAGARSGTVELASAveEAAKSSNRPAPKYLPLTVEMSNRESVEEAAADVEREFGRCDIIVNNAGIFGgFQLIE 152
                 79******************************744333321033333333455888899999*****************************9769**** PP

                 T--HHHHHHHHTTTTHHHHHHHHHTTT...S--S.EEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHH CS
          KR  99 emtaedleqvlapKvkGawnLhelled...esld.ffvlfSSiagllgsagqanYaaaNaflDalaey 162
                 e + +++++++   v+G   + ++l +   ++ d ++v +SS+++ll +++ ++Y+   + +  lae 
  EEA18950.1 153 EYDPDMWTNIFDVNVRGPYLITRALIPlmlKTGDaYMVNVSSAGALLTNRTLSAYQISKTAVTRLAEF 220
                 *****************9999998888555333437999****************9999988888876 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.1   4.4e-06     0.016       1     161 [.      54     226 ..      54     232 .] 0.69

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 4.4e-06
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC............EEEE--TT-HHHHHHHHHH....H.T-SEEEE--S.---HHHHH CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl............elveldltdrsalerlfke....e.qpdavihlAa.vggvaass 81 
                 +l+tG++  iG+a+v a +++g   i+   +s + + a+  +                ++++ +r+++e++ ++    + ++d++++ A+  gg +   
  EEA18950.1  54 VLITGGSRGIGRAIVLAYAKAGASFIAAGARSGTVELASAVEEaakssnrpapkyLPLTVEMSNRESVEEAAADvereFgRCDIIVNNAGiFGGFQLIE 152
                 79**********************9999999777777766666899*******9955566666666555554431111348*********999999999 PP

                 HSHHHHHHHHTHHHHHHHHHHHHHTCTEEEEEEEGGGGTSCSSSSBSTCSTTS--.--SSHHHHHHHHHHHHHHHHHHHHT CS
   Epimerase  82 edpadfieknlqgtlnlleaarkagvkrllflsSsevYGkdaeqpkeettltgpl.kpnspYaaaKlageklveayaaqyg 161
                 e+  d++ + + ++++    + +a +   l l +   Y  + +      +l   + ++ s+Y ++K+a+ +l+e ++++y 
  EEA18950.1 153 EYDPDMWTNIFDVNVRGPYLITRALI--PLMLKTGDAYMVNVS--SAGALL---TnRTLSAYQISKTAVTRLAEFVNEEYS 226
                 99988876655444444444444433..233333333332222..122221...127789999999999999999999995 PP

>> QRPTase_C  Quinolinate phosphoribosyl transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.3   0.00018      0.66      60      99 ..      88     128 ..      44     142 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00018
                 HHHHSSHHHHHHHHHHHHTTTSEEEEEESSHHHHHHHHH.H CS
   QRPTase_C  60 iaaagsiveavksvreavdkevkievevesleeleevle.a 99 
                 + +a+ ++ea ks +  ++k ++++ve+++ e +ee+++ +
  EEA18950.1  88 VELASAVEEAAKSSNRPAPKYLPLTVEMSNRESVEEAAAdV 128
                 5678899*****************************98742 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (232 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       429  (0.0239277); expected 358.6 (0.02)
Passed bias filter:                      396  (0.0220871); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 1669.45
//
Query:       EEA18951.1  [L=72]
Description: hypothetical protein PMAA_012220 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (72 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       197  (0.0109878); expected 358.6 (0.02)
Passed bias filter:                      187  (0.01043); expected 358.6 (0.02)
Passed Vit filter:                         5  (0.000278878); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.24s 00:00:00.64 Elapsed: 00:00:00.42
# Mc/sec: 515.61
//
Query:       EEA18952.1  [L=1366]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.011   15.7   4.7         31    5.0   0.0    6.7  8  LRR_6     Leucine Rich repeat
      0.028   14.9   0.8    2.2e+02    3.1   0.0    6.6  6  LRR_1     Leucine Rich Repeat


Domain annotation for each model (and alignments):
>> LRR_6  Leucine Rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0      0.04   3.6e+02       1      13 [.     599     611 ..     599     622 .. 0.91
   2 ?    0.2   0.0      0.12   1.1e+03       3      15 ..     671     683 ..     670     684 .. 0.89
   3 ?   -2.8   0.0       1.1   9.7e+03       5      23 ..     757     775 ..     756     776 .. 0.74
   4 ?    0.1   0.0      0.12   1.1e+03       2      18 ..     784     800 ..     783     805 .. 0.86
   5 ?   -2.8   0.1         1   9.2e+03       7      16 ..     820     829 ..     820     830 .. 0.87
   6 ?    5.0   0.0    0.0035        31       1      11 [.     870     880 ..     870     883 .. 0.92
   7 ?    1.9   0.0     0.033     3e+02       2      12 ..     903     913 ..     902     913 .. 0.90
   8 ?   -2.3   0.0      0.73   6.5e+03       1      20 [.     936     955 ..     936     959 .. 0.74

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.04
       LRR_6   1 snthLteLdLsgN 13 
                 +n  L+ Ld s++
  EEA18952.1 599 KNKRLRRLDFSFC 611
                 5899*******98 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.12
       LRR_6   3 thLteLdLsgNdI 15 
                 +hL++L++  +++
  EEA18952.1 671 SHLRALEVGECGL 683
                 7*******99987 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 1.1
       LRR_6   5 LteLdLsgNdIgDeGaeaL 23 
                 L+eL+Ls   ++ e +e++
  EEA18952.1 757 LEELSLSQTAVNKETVESI 775
                 89****9877777666666 PP

  == domain 4  score: 0.1 bits;  conditional E-value: 0.12
       LRR_6   2 nthLteLdLsgNdIgDe 18 
                 +++L+ L L  +++++ 
  EEA18952.1 784 SSSLRILRLDQCGLTGG 800
                 689**********9975 PP

  == domain 5  score: -2.8 bits;  conditional E-value: 1
       LRR_6   7 eLdLsgNdIg 16 
                 +L++s N+++
  EEA18952.1 820 HLHVSENHLD 829
                 79*****986 PP

  == domain 6  score: 5.0 bits;  conditional E-value: 0.0035
       LRR_6   1 snthLteLdLs 11 
                 +nt+L++Ld+s
  EEA18952.1 870 KNTTLKYLDIS 880
                 69********9 PP

  == domain 7  score: 1.9 bits;  conditional E-value: 0.033
       LRR_6   2 nthLteLdLsg 12 
                 n +L+eLd+sg
  EEA18952.1 903 NETLEELDISG 913
                 89*******96 PP

  == domain 8  score: -2.3 bits;  conditional E-value: 0.73
       LRR_6   1 snthLteLdLsgNdIgDeGa 20 
                 +n +L+ L + + ++g +Ga
  EEA18952.1 936 KNKSLKVLRIEHQKLGLQGA 955
                 5999****998766666665 PP

>> LRR_1  Leucine Rich Repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.0     0.082   7.3e+02       1      12 [.     602     613 ..     602     633 .. 0.75
   2 ?    3.1   0.0     0.025   2.2e+02       1      22 [.     786     807 ..     786     808 .. 0.88
   3 ?   -1.3   0.0      0.66   5.9e+03       2       9 ..     874     881 ..     873     892 .. 0.85
   4 ?   -0.8   0.0      0.47   4.2e+03       2       9 ..     906     913 ..     905     920 .. 0.88
   5 ?   -0.1   0.0      0.26   2.4e+03       1      15 [.     939     953 ..     939     961 .. 0.77
   6 ?   -2.1   0.1       1.2   1.1e+04       1      12 [.     967     978 ..     967     991 .. 0.75

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.082
       LRR_1   1 nLrhLdLsnnpl 12 
                 +Lr+Ld s +  
  EEA18952.1 602 RLRRLDFSFCLS 613
                 69****999976 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.025
       LRR_1   1 nLrhLdLsnnpllglppnsfqn 22 
                 +Lr L L ++ l+g   ++f  
  EEA18952.1 786 SLRILRLDQCGLTGGDVATFLR 807
                 69**********9999988875 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.66
       LRR_1   2 LrhLdLsn 9  
                 L++Ld+s 
  EEA18952.1 874 LKYLDISK 881
                 9*****85 PP

  == domain 4  score: -0.8 bits;  conditional E-value: 0.47
       LRR_1   2 LrhLdLsn 9  
                 L++Ld+s+
  EEA18952.1 906 LEELDISG 913
                 9*****97 PP

  == domain 5  score: -0.1 bits;  conditional E-value: 0.26
       LRR_1   1 nLrhLdLsnnpllgl 15 
                 +L++L ++++ l+  
  EEA18952.1 939 SLKVLRIEHQKLGLQ 953
                 69********99544 PP

  == domain 6  score: -2.1 bits;  conditional E-value: 1.2
       LRR_1   1 nLrhLdLsnnpl 12 
                 +L++++ +nn  
  EEA18952.1 967 SLQEIYCENNDM 978
                 699999999984 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1366 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       485  (0.0270511); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.79u 0.30s 00:00:01.09 Elapsed: 00:00:00.48
# Mc/sec: 8631.74
//
Query:       EEA18953.1  [L=150]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (150 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       487  (0.0271627); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.45
# Mc/sec: 1008.44
//
Query:       EEA18954.1  [L=244]
Description: imidazoleglycerol-phosphate dehydratase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.5e-56  189.5   0.4    5.9e-56  188.8   0.5    1.4  2  IGPD           Imidazoleglycerol-phosphate dehydratase
  ------ inclusion threshold ------
        0.2    8.8   0.0       0.25    8.5   0.0    1.0  1  Arena_RNA_pol  Arenavirus RNA polymerase


Domain annotation for each model (and alignments):
>> IGPD  Imidazoleglycerol-phosphate dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0       1.7   1.5e+04      69      86 ..      15      32 ..       6      39 .. 0.63
   2 !  188.8   0.5   6.6e-60   5.9e-56       1     144 []      77     220 ..      77     220 .. 0.99

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 1.7
                TTEEEEEEEE--SS-EEE CS
        IGPD 69 Dealaevaldlsgrpylv 86
                +e+ ++v+l l g   l 
  EEA18954.1 15 NETKIQVSLSLDGGVLLP 32
                566666666666655555 PP

  == domain 2  score: 188.8 bits;  conditional E-value: 6.6e-60
                 ....HHHHHHHHHHHHHT--EEEEEEESSH...HHHHHHHHHHHHHHHHHHS..-SSB--EEEEEEEETTEEEEEEEE--SS-EEE--..-SB--TT.- CS
        IGPD   1 TgigfldhmLdqlakhggfdlkvkvkgdlevddHhtvedvgialGqalkealgdkrgikRfgsallpmDealaevaldlsgrpylvleaelkrekigel 99 
                 TgigfldhmL++lakh+g++l++++kgdl +ddHht+ed+++ lG+a+++alg ++ ++Rfg+  +p+Deal+++++dls+rpy v++  +krekig+l
  EEA18954.1  77 TGIGFLDHMLHALAKHSGWSLAIRAKGDLFIDDHHTTEDTMLGLGTAFTKALGARTSLARFGRGDAPLDEALSWAVIDLSNRPYAVIDLGFKREKIGDL 175
                 9************************************************************************************************** PP

                 -HHHHHHHHHHHHHHHT-EEEEEEEE--BHHHHHHHHHHHHHHHH CS
        IGPD 100 dtelveeffeslaeaagitlhvkvlrgenahhivealfKafaraL 144
                 +te++ + +es+a+aag+tlh+ +++g+n+hh +e++fKa+a a+
  EEA18954.1 176 STEMITHGLESFAQAAGVTLHIGCSYGSNDHHRAESAFKALAVAI 220
                 ******************************************996 PP

>> Arena_RNA_pol  Arenavirus RNA polymerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.0   2.8e-05      0.25     958    1008 ..     169     221 ..     163     238 .. 0.74

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 2.8e-05
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXX CS
  Arena_RNA_pol  958 relyiGdlrtklftrliedyfeavssslsgsclnnekef...enailsmklnvs 1008
                     re  iGdl t ++t  +e +++a + +l   c     +    e a   + ++++
     EEA18954.1  169 RE-KIGDLSTEMITHGLESFAQAAGVTLHIGCSYGSNDHhraESAFKALAVAIR 221 
                     55.59************************9997544444001445555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (244 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       312  (0.017402); expected 358.6 (0.02)
Passed bias filter:                      280  (0.0156172); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1697.97
//
Query:       EEA18955.1  [L=220]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (220 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       252  (0.0140554); expected 358.6 (0.02)
Passed bias filter:                      228  (0.0127168); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.41u 0.24s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1638.54
//
Query:       EEA18956.1  [L=351]
Description: MIPC synthase subunit (SurA), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.8e-22   78.4   0.0    9.1e-22   77.5   0.0    1.4  1  Gly_transf_sug  Glycosyltransferase sugar-binding region cont
  ------ inclusion threshold ------
       0.13   12.7   2.4       0.25   11.8   2.4    1.4  1  SCIMP           SCIMP protein
       0.37   10.0   1.6        0.7    9.1   0.3    1.8  2  TcdA_TcdB       TcdA/TcdB catalytic glycosyltransferase domai


Domain annotation for each model (and alignments):
>> Gly_transf_sug  Glycosyltransferase sugar-binding region containing DXD motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.5   0.0   1.5e-25   9.1e-22       1      92 [.      73     155 ..      73     160 .. 0.96

  Alignments for each domain:
  == domain 1  score: 77.5 bits;  conditional E-value: 1.5e-25
  Gly_transf_sug   1 perekkaieslakahpdyqvvvlskelekvrvaildlefllsdtpwfeeakkllplfialsDllRlaiLykyGGiYlDtDvivlkslrnsig 92 
                     per+++ ++s+++ hpdy+++++++e +         ef++ ++pwf+e+++ ++++i+++D++R+++L +yGG+YlD+D  + ++l ++++
      EEA18956.1  73 PERWIEPQRSCIDLHPDYEYILWTNEKS--------REFIAAEYPWFLETFDGYTYPIQRADAIRYFVLAHYGGVYLDLDDGCHRRL-DPLL 155
                     899***********************99........**************************************************9.8887 PP

>> SCIMP  SCIMP protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   2.4   4.2e-05      0.25       2      45 ..     262     305 ..     261     311 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 4.2e-05
       SCIMP   2 swWrdnfWiilavaiivvsvvlglilycvcrrllrqGkkweiak 45 
                  +W   +W++l+va   ++  +g+ +++v+ rll  G++++ ++
  EEA18956.1 262 IFWMCRYWVLLTVAGFTIAGCVGFCMWIVYGRLLLLGHRYRYSR 305
                 58***********************************9998765 PP

>> TcdA_TcdB  TcdA/TcdB catalytic glycosyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0      0.11   6.7e+02       1      39 [.      61      99 ..      61     107 .. 0.91
   2 ?    9.1   0.3   0.00012       0.7     201     220 ..     125     144 ..     124     145 .. 0.95

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.11
                SEEEEE--SS---HHHHHHHHHHHHHTTTSEEEEEE-TT CS
   TcdA_TcdB  1 KklHfvwigGkitdiqedYinvwldvnedydinlwvDsn 39
                K++H  +i   i++   +  +  +d ++dy+  lw  ++
  EEA18956.1 61 KIIHQTYINESIPERWIEPQRSCIDLHPDYEYILWTNEK 99
                89999999999999999999***************8775 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.00012
                 HHHHHHHHHHHH-EEEE-TT CS
   TcdA_TcdB 201 sDivRllvLkelGGlyldvD 220
                 +D +R  vL  +GG+yld+D
  EEA18956.1 125 ADAIRYFVLAHYGGVYLDLD 144
                 599****************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (351 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       445  (0.0248201); expected 358.6 (0.02)
Passed bias filter:                      306  (0.0170673); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2527.97
//
Query:       EEA18957.1  [L=258]
Description: ER-associated proteolytic system protein Der1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.9e-49  166.9   2.8    5.8e-49  166.6   2.8    1.0  1  DER1      Der1-like family


Domain annotation for each model (and alignments):
>> DER1  Der1-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  166.6   2.8   3.2e-53   5.8e-49       1     190 [.      23     212 ..      23     213 .. 0.91

  Alignments for each domain:
  == domain 1  score: 166.6 bits;  conditional E-value: 3.2e-53
        DER1   1 iPavTRllltatvvltllgrlelispaklvlsyelvvkkvQiwRlltsllyfsstgfsflinlyfiyqysskLEegsfrgrsadyvylllflavlitll 99 
                 +P+ TR +++atv++++l+++e +sp++l++s  +v  + Q+wR+lt++lyf+ ++++ l++++f+ +ys+ LEe+  ++++a + +ll+  +  + +l
  EEA18957.1  23 MPPCTRWWTAATVATSVLVQCEAVSPMQLYYSLPAVYVRSQYWRILTTFLYFGPLNLDLLFHVFFLQRYSRLLEES-SGRSPAYFSWLLFYAMSSLLIL 120
                 7**************************************************************************9.3445566666666665555555 PP

        DER1 100 glla.dlvvLgqalilaivYvwskknkdvqvsFfgvlrvkakylPlvllafsfllgesvv.vsligilvghiyyfledkypiklnGkdllktP 190
                 +  + +l  Lgqal +++vY+ws++n+d+++sF+g+l ++a+ylP+vl+af+fl++++v   ++ g++vgh+ yf++d+yp   +G++ l  P
  EEA18957.1 121 SP-FvSLPYLGQALSSTLVYIWSRRNPDTRLSFLGLLVFTAPYLPWVLMAFHFLVHGTVPkDDICGVIVGHVWYFFSDVYPSLHDGHRPLDPP 212
                 55.5489**************************************************88747899*******************999877655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (258 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       443  (0.0247086); expected 358.6 (0.02)
Passed bias filter:                      298  (0.0166211); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.25s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1911.33
//
Query:       EEA18958.1  [L=849]
Description: mitochondrial mRNA processing protein PET127, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   5.9e-122  406.4   0.9   9.4e-122  405.7   0.9    1.3  1  Pet127    Mitochondrial protein Pet127


Domain annotation for each model (and alignments):
>> Pet127  Mitochondrial protein Pet127
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  405.7   0.9  5.2e-126  9.4e-122       1     274 []     239     512 ..     239     512 .. 0.97

  Alignments for each domain:
  == domain 1  score: 405.7 bits;  conditional E-value: 5.2e-126
      Pet127   1 fvtsskdkeLlelakeekkkyvsStSsltsvLsqlylllsnfrklnlsslskafeekskkftklarlpasvilrkkekvyaidsdksldkeiiLsalGk 99 
                 ++tsskd++L+ela+++kkkyv+S+Ss+tsvLs++++llsn+r+l+ + +s+ fe+++++ft+l r p++++l++k++vyaid+dk++d+++iL++lGk
  EEA18958.1 239 YITSSKDETLIELARKTKKKYVGSSSSMTSVLSHFHYLLSNWRPLKQDIISRGFEDSDRQFTRLLRGPSAMFLHYKDGVYAIDADKEFDSANILMNLGK 337
                 99************************************************************************************************* PP

      Pet127 100 slEklLtleeeefekylkkeksekakeeekk..eaYnysklgkfllrsqLDcydprlpgtgvFdlKtRavvaiRydleeveketgyeikklkgefeSfe 196
                 s+Ek+Ltl++e+fe+y+++  ++ + eee++  e+Y+ys+lg+f++rsqLD+ydprlpg+g+FdlKtRavv+iR++++++e++ gyei++++g+feSfe
  EEA18958.1 338 SMEKQLTLPKEQFERYRRSAPNKITPEEENEvpESYHYSTLGDFVMRSQLDAYDPRLPGSGMFDLKTRAVVSIRMSVSDYEQGLGYEIRNRFGSFESFE 436
                 ******************997666666666689****************************************************************** PP

      Pet127 197 rEyydlirsalLKYslQariGqmdGifvaYHnikrifGfqYlpleeldkvlfgeeelaskladkeFklslelleklld 274
                 rEyyd+ir+a+LKYslQ+riG+mdGifva+Hni+rifGfqY+pl+e+d++l+g+++  ++l+d+eF++s++l++k+ld
  EEA18958.1 437 REYYDMIRAAFLKYSLQVRIGRMDGIFVAFHNIERIFGFQYVPLSEMDYALHGQSD--TELGDREFQYSIKLWNKILD 512
                 *****************************************************777..56****************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (849 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1794  (0.100061); expected 358.6 (0.02)
Passed bias filter:                      738  (0.0411624); expected 358.6 (0.02)
Passed Vit filter:                        83  (0.00462937); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.84u 0.29s 00:00:01.12 Elapsed: 00:00:00.45
# Mc/sec: 5703.60
//
Query:       EEA18959.1  [L=820]
Description: bifunctional purine biosynthetic protein Ade1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    9.9e-84  279.9   0.0    2.4e-83  278.7   0.0    1.6  2  GARS_A       Phosphoribosylglycinamide synthetase, ATP-grasp 
    6.8e-35  119.7   0.0    2.3e-34  118.0   0.0    2.0  1  GARS_N       Phosphoribosylglycinamide synthetase, N domain
      1e-29  103.6   0.0    3.2e-29  102.1   0.0    1.8  1  AIRS_C       AIR synthase related protein, C-terminal domain
    3.1e-26   91.5   0.4    8.5e-26   90.1   0.4    1.8  1  GARS_C       Phosphoribosylglycinamide synthetase, C domain
    2.7e-14   53.6   3.2    6.7e-14   52.3   2.5    2.1  1  AIRS         AIR synthase related protein, N-terminal domain
    0.00015   21.4   0.0    0.00025   20.7   0.0    1.3  1  ATP-grasp    ATP-grasp domain
    0.00047   20.2   0.0     0.0017   18.4   0.0    1.9  2  ATP-grasp_3  ATP-grasp domain
    0.00062   19.3   0.0     0.0013   18.3   0.0    1.5  1  CPSase_L_D2  Carbamoyl-phosphate synthase L chain, ATP bindin
  ------ inclusion threshold ------
      0.018   14.6   0.0      0.036   13.7   0.0    1.5  1  ATP-grasp_4  ATP-grasp domain
        0.1   11.8   0.0        0.4    9.9   0.0    1.8  2  ATPgrasp_ST  Sugar-transfer associated ATP-grasp
       0.15   11.6   0.0       0.33   10.5   0.0    1.5  1  ATP-grasp_2  ATP-grasp domain


Domain annotation for each model (and alignments):
>> GARS_A  Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  278.7   0.0   1.5e-86   2.4e-83       1     194 []     110     302 ..     110     302 .. 1.00
   2 ?   -2.6   0.0       2.3   3.8e+03       4      24 ..     685     705 ..     683     713 .. 0.82

  Alignments for each domain:
  == domain 1  score: 278.7 bits;  conditional E-value: 1.5e-86
                 HBHHHHHHHHHHTT--B--EEEESSHHHHHHHHHHHSSSEEEEEESC-GGGT-EEEESSHHHHHHHHHHHCTS-TTCCCCSSEEEEE---SEEEEEEEE CS
      GARS_A   1 asKsfakdllkkagiptaeyeaftdpeeakeyieeatakalVvKadglaagKgvivakseeealkavkeilekkkfGeagekvviEelleGeEvsllal 99 
                 +sK+f+kd++k+++ipta ye+ftd+e+a++y++++t+++ V+Ka+glaagKgvi+++++eea ka++ei+ +++fG ag++vviEe+leG+E+s+l++
  EEA18959.1 110 GSKAFSKDFMKRHNIPTAAYENFTDYEAARKYLDSVTHDV-VIKASGLAAGKGVIIPTTKEEAHKALREIMLDHQFGAAGDEVVIEEFLEGDELSILTF 207
                 69**************************************.********************************************************** PP

                 ECTTEEEE---BEEEEEEECCCEEEEECECEEEES-TTS-HHHHHHHHHHTHHHHHHHHHCTT---EEEEEEEEEEETTEEEEEEEESS--TTCH CS
      GARS_A 100 vdgktvkplplaqdhkrvlegDkgpnTGGmGayspapvvteellekikeeileptveglkkegipfkGvLyaglmlvedgpkvlefnvRfgDpet 194
                 +dg+++k+lp+aqdhkrv++gD+gpnTGGmG+y+p+ ++++++le+i   i++p ++g+++eg pf+G+L++glm++++gpkvle+nvR gDpet
  EEA18959.1 208 SDGYSIKSLPPAQDHKRVFDGDQGPNTGGMGCYAPTRIASKDVLEQIDRDIVQPSIDGMRREGFPFVGILFTGLMMTKNGPKVLEYNVRGGDPET 302
                 **********************************************************************************************8 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 2.3
                 HHHHHHHHHTT--B--EEEES CS
      GARS_A   4 sfakdllkkagiptaeyeaft 24 
                  + k llk+ +ip++++++ t
  EEA18959.1 685 IYVKPLLKALNIPSSQHTTST 705
                 6899**********9887654 PP

>> GARS_N  Phosphoribosylglycinamide synthetase, N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.0   0.0   1.4e-37   2.3e-34       2      90 .]       7     109 ..       6     109 .. 0.96

  Alignments for each domain:
  == domain 1  score: 118.0 bits;  conditional E-value: 1.4e-37
                 EEEEEESSHHHHHHHHHHTTSTTESEEEEEE--CGG...............TTHHHHHHHHHHCTESEEEE-SHHHHHTTHHHHHHHHHT-EEES--CC CS
      GARS_N   2 kvLvvGsGGRehalawklaqspkvekvyvapgNagt...............edlealvefakeekidlvvvGpeapLvaGvadaleeekgikvfGpske 85 
                 ++LvvG+GGReha+awkl+qsp+v+ vyvapgN+gt               +d+ +lv+fa++++++lvv+GpeapLv+G++ ++++  gi++fGp+k+
  EEA18959.1   7 RILVVGNGGREHAFAWKLSQSPSVDVVYVAPGNGGTglgasskivnaavksDDYPSLVAFAQKNNVNLVVPGPEAPLVDGIQGYFQAV-GIRCFGPTKA 104
                 8****************************************999999988877889*****************************666.********** PP

                 CCHHH CS
      GARS_N  86 aAqlE 90 
                 aA++E
  EEA18959.1 105 AARME 109
                 ****9 PP

>> AIRS_C  AIR synthase related protein, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.1   0.0     2e-32   3.2e-29       1     148 [.     620     802 ..     620     807 .. 0.96

  Alignments for each domain:
  == domain 1  score: 102.1 bits;  conditional E-value: 2e-32
                 STTEEEEEEETSSCTCCHHHHHHHCHHHCTSHTT.................TSE.HHHHHHHHHHHHHHHHHHHH..........HTTECEEEE--TTH CS
      AIRS_C   1 kpGdvliltgslGlggagtslkrkileeegldds.................avq.lgdvlleptliyvkralaal..........kglvkaahDvTgGG 71 
                 kpGd+l+ ++s G++++g+sl+rki++++gl ++                 + q lg +ll+pt+iyvk++l al          +  +k+++++TgGG
  EEA18959.1 620 KPGDTLLALASAGVHSNGFSLVRKIVDHSGLTYNdkvpfafsapassslatKPQtLGTALLTPTRIYVKPLLKALnipssqhttsTAAIKGMAHITGGG 718
                 79******************************99****************96667********************99*9999999999*********** PP

                 HHHHHHHHHHTTTEEEEEECG...THHHHHHHH.....HHHHHHHCSTTTEEEEEEEHGGH.HHHHHHHHHTTCCCEEEEEEEEES CS
      AIRS_C  72 Llgalaemapasgvgaeidld...kvpifdele.....splemllsensGrllvavppeea.davlaileeeglpeaavIGevtak 148
                 L++++++m+p   ++a+id++    +p+f++l+     s +em +++n+G+++++v+  +  dav++ le+ g+ +++ IGe+  +
  EEA18959.1 719 LIENVPRMLPPT-LSAHIDVSawtLPPVFQWLKktgnvSSQEMSRAFNCGVGMILVVDSDCvDAVKQSLEQDGE-TVYKIGELKVR 802
                 ***********8.*************************************************************.7******8765 PP

>> GARS_C  Phosphoribosylglycinamide synthetase, C domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.1   0.4   5.2e-29   8.5e-26       2      80 .]     340     427 ..     339     427 .. 0.96

  Alignments for each domain:
  == domain 1  score: 90.1 bits;  conditional E-value: 5.2e-29
                 EEEEEEETTTTSS--ST-EEBS....TTEEEEESSEE.....EEE-SSEEEEEEEEESSHHHHHHHHHHHHTTCB-TTEE--STTTHH CS
      GARS_C   2 vgvvlaskGYPgsyekgkeitg....egvkvfhagtk.....lvtsGGRvlavvavgetleeArakayeavkkikfeglfyRkDIGar 80 
                 ++v+++++GYPgsy+kg++it     +++ +fhagt+     l t+GGRv+a++++++tleeA +++y ++++i+f+g++yRkDI++r
  EEA18959.1 340 ATVIAVAGGYPGSYAKGTPITLdatpDDTLIFHAGTSlvdnvLQTAGGRVIAATSIASTLEEAVRRSYVGISTIHFDGMHYRKDIAHR 427
                 79******************889***8899*******999989*******************************************97 PP

>> AIRS  AIR synthase related protein, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.3   2.5   4.1e-17   6.7e-14      10      92 ..     503     600 ..     474     602 .. 0.84

  Alignments for each domain:
  == domain 1  score: 52.3 bits;  conditional E-value: 4.1e-17
                 EEEE.EECCTCCCC....HHHHHHHHHHHHHHTTTEEEEEEEEEEEEC.....HHHHHHHHHHHHHHHTT-EEEEEEEEEESS......EEEEEEEEE CS
        AIRS  10 dshnrpvlvepvhf....iGakavavnlsDlaamGArPlalllslalp.....wleevvrglaeaaeelgvplvgGdtsfsne......ptisvtavG 92 
                 d++++++ ++   +    +G  +va+n++Dl++ GA+Pl++l++++++     +++++v+g+ae++ ++g++l+gG+t+++++      +  + +avG
  EEA18959.1 503 DGVGTKLKIAHAVGihdtVGIDLVAMNVNDLVVQGAEPLFFLDCYSCGkldvqTAAAFVTGVAEGCYQAGCALIGGETAEMPGlflddaYDAVGAAVG 600
                 5555555555444467789************************************************************9988766666666666666 PP

>> ATP-grasp  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.7   0.0   1.5e-07   0.00025       2      86 ..     120     210 ..     119     228 .. 0.87

  Alignments for each domain:
  == domain 1  score: 20.7 bits;  conditional E-value: 1.5e-07
                 HTTT--B-EEEEECCHHHHHHHHHHH-SCEEEEESSS-CTTTTEEEECTCCGHHCHHHHC........GTTCEEEEE----SEEEEEEEEEET CS
   ATP-grasp   2 eklglpvprflaveskeeleeaaeelglpvvvKarrlgydGkGqsvvrseedleqaleal........keekvivEefvpfekElsvlvvrsa 86 
                 +++++p++ +   ++ e++++ ++++   vv+K + +   GkG  +   +e++++al+++        ++ +v++Eef +   Els+l+  + 
  EEA18959.1 120 KRHNIPTAAYENFTDYEAARKYLDSVTHDVVIK-ASGLAAGKGVIIPTTKEEAHKALREImldhqfgaAGDEVVIEEFLEG-DELSILTFSDG 210
                 689******************************.556668******************999*****99999*******995.59999987654 PP

>> ATP-grasp_3  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.0     1e-06    0.0017       4     157 ..     112     296 ..     110     298 .. 0.66
   2 ?   -2.5   0.1       2.8   4.6e+03     131     151 ..     515     534 ..     507     536 .. 0.72

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 1e-06
                  HHHHHHHHTTT.S---........-EESS--.....SSSEEEEESS-------B--SS--TTE...................EEEE---SEEEEEEEE CS
  ATP-grasp_3   4 KlktykkLkeagvkvP....tkleaeeleee.....ekklvvKprdGaggesvrvveekeeaeaaieeve............lvqefieGkplSvsll 80 
                  K ++ +++k++  ++P    ++ +++e++++      + +v+K +  a+g++v +   keea++a+ e+             ++ ef+eG++lS+ + 
   EEA18959.1 112 KAFSKDFMKRH--NIPtaayENFTDYEAARKyldsvTHDVVIKASGLAAGKGVIIPTTKEEAHKALREIMldhqfgaagdevVIEEFLEGDELSILTF 207
                  66677778888..55554885555555555555566999***************************999999************************** PP

                  E.SSSEEEEEEEEEEEET.........TEEEEEEES----HHHHHHHHHHHHHT.TST....T--EEEEE...EEEESS.SEEEEEEESS CS
  ATP-grasp_3  81 sdgekvlvlavnrqliekaeke.....fvyaGnvtpietelkeevvelaeevve.kle....glaGyvGv...DlvlkdeepyviEvNPR 157
                  sdg  ++ l   + +      +         G+ +p +   k+ ++++ +++v+ ++     + + +vG+    l++++++p v+E N R
   EEA18959.1 208 SDGYSIKSLPPAQDHKRVFD-GdqgpnTGGMGCYAPTRIASKDVLEQIDRDIVQpSIDgmrrEGFPFVGIlftGLMMTKNGPKVLEYNVR 296
                  **988887765544432211.124555555555556665555555555555554223211132222333311134466677777777665 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 2.8
                  STT--EEEEEEEEESS.SEEE CS
  ATP-grasp_3 131 leglaGyvGvDlvlkdeepyv 151
                  + g+   vG+Dlv  + ++ v
   EEA18959.1 515 V-GIHDTVGIDLVAMNVNDLV 534
                  4.778899*****87755554 PP

>> CPSase_L_D2  Carbamoyl-phosphate synthase L chain, ATP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   8.1e-07    0.0013       4      91 ..     114     199 ..     111     205 .. 0.92

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 8.1e-07
                  HHHHHHHHTT-BBSSEECSSBSSHHHHHHHHHHH-SSEEEEETTCCTTTTEEEESSHHHHHHHHHHHHHHHHHHHSTS-EEEEE--SS CS
  CPSase_L_D2   4 sakealkkinvpvvpssaapvetleealaiakeigyPviikaafglGGkGmrvarneeelaelvkkalaeakaafgnkqvlvekslkg 91 
                   +k+ +k+ n+p++  ++   ++ e a +  +++ + v+ika+    GkG  + +++ee ++++++ +   +   + ++v +e++l+g
   EEA18959.1 114 FSKDFMKRHNIPTAAYENF--TDYEAARKYLDSVTHDVVIKASGLAAGKGVIIPTTKEEAHKALREIMLDHQFGAAGDEVVIEEFLEG 199
                  568899999***9999988..9*******************************************99999986777899******986 PP

>> ATP-grasp_4  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   2.2e-05     0.036       4      72 ..     148     208 ..     145     215 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 2.2e-05
  ATP-grasp_4   4 PvviKPsvgffSlGVykinneeewkaavaaieeeleqakeeykeevveeesflvEeyieGeEfavdayf 72 
                   vviK s  ++  GV++  ++ee ++a+++i  +     +++      ++++++Ee++eG+E ++  + 
   EEA18959.1 148 DVVIKASGLAAGKGVIIPTTKEEAHKALREIMLD-----HQFG---AAGDEVVIEEFLEGDELSILTFS 208
                  69************************99999866.....3444...3588999**********997665 PP

>> ATPgrasp_ST  Sugar-transfer associated ATP-grasp
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0   0.00025       0.4      22      86 ..     112     172 ..     102     202 .. 0.79
   2 ?   -1.4   0.0      0.68   1.1e+03     239     265 ..     271     296 ..     268     303 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00025
  ATPgrasp_ST  22 KlkfkelalraglkvpkllgvikeqaeiseleafvkeleegvviKpakgsgGkGilviteredqd 86 
                  K   k++++r+ +++ +     ++  + +++++++ ++ ++vviK+    +GkG+++ t +e+++
   EEA18959.1 112 KAFSKDFMKRHNIPTAA----YENFTDYEAARKYLDSVTHDVVIKASGLAAGKGVIIPTTKEEAH 172
                  55666777777766666....6666999999*******999*****************9855443 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.68
  ATPgrasp_ST 239 lpglgylGwDivldeekgplllElNar 265
                  +p +g+l + + +++++ p +lE N r
   EEA18959.1 271 FPFVGILFTGLMMTKNG-PKVLEYNVR 296
                  6678888888999***9.*******87 PP

>> ATP-grasp_2  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0    0.0002      0.33       7      76 ..     115     179 ..     113     198 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.0002
                  HHHHHHCTT----SEEEESSHHHHHHHHHHHTSSSEEEEE--SSSTCCCTTCEEEESSHHHHHHHHHCCT CS
  ATP-grasp_2   7 akeilakygvkvpegevaesaeeaeeaakklgekelvvKaQvlaGGRGKagGvklvkskeeakeaakell 76 
                  +k+ +++++++++  e  ++ e a++ ++++ +++ v+Ka  la G+    Gv + ++keea++a +e++
   EEA18959.1 115 SKDFMKRHNIPTAAYENFTDYEAARKYLDSVTHDV-VIKASGLAAGK----GVIIPTTKEEAHKALREIM 179
                  7999**************************98887.****9998876....6999999999999888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (820 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       459  (0.025601); expected 358.6 (0.02)
Passed bias filter:                      436  (0.0243181); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.71u 0.31s 00:00:01.02 Elapsed: 00:00:00.50
# Mc/sec: 4959.27
//
Query:       EEA18960.1  [L=375]
Description: actin Act1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.7e-150  501.2   0.0   6.1e-150  499.3   0.0    1.7  1  Actin     Actin


Domain annotation for each model (and alignments):
>> Actin  Actin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  499.3   0.0  3.4e-154  6.1e-150       2     407 .]       3     375 .]       2     375 .] 0.98

  Alignments for each domain:
  == domain 1  score: 499.3 bits;  conditional E-value: 3.4e-154
       Actin   2 devsavVlDnGssttraGyagedaPkavipslvgkprgrkvea.....klyvgdealtkrpelevrspvedGvvedwdaveelwehvlkeelkvdpeeh 95 
                 +ev a+V+DnGs++++aG+ag+daP+av+ps+vg+pr++  +      + yvgdea++kr+ l++r+p+e+Gvv++wd++e++w+h++++el+v peeh
  EEA18960.1   3 EEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHHGIMIgmgqkDSYVGDEAQSKRGILTLRYPIEHGVVTNWDDMEKIWHHTFYNELRVAPEEH 101
                 689************************************9887999999************************************************** PP

       Actin  96 pllltepplnppkqrekalEivfEkfkvpalylaksavlsafasgkstglvvDsGasvtsvvpVldGyvLkkairrsdlgGkaLteqlkellssknvev 194
                 p+llte+p np+++rek+++ivfE+f+ pa+y++ +avls++asg++tg+v+DsG++vt+vvp+++G++L +ai r+d++G++Lt++l+++l ++    
  EEA18960.1 102 PVLLTEAPINPKSNREKMTQIVFETFNAPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTHVVPIYEGFALPHAISRVDMAGRDLTDYLMKILAER---- 196
                 **********************************************************************************************8.... PP

       Actin 195 tprylikkkkvveaessaekeelekltesyktleeeevleeiKesvcevsedpeg..deeksssspeksYeLPDgseiklgeeRfkvpEiLFdpsligs 291
                                           ++s++t++e+e++++iKe++c+v+ d+e+  +++++sss eksYeLPDg++i++g+eRf++pE+LF+ps ig 
  EEA18960.1 197 --------------------------GYSFSTTAEREIVRDIKEKLCYVALDFEQeiQTASQSSSLEKSYELPDGQVITIGNERFRAPEALFQPSVIGL 269
                 ..........................9***************************977777778************************************ PP

       Actin 292 esaleeekskllgiselivaainacdvdlrpeLlanivvtGGnsllpglteRlekelaqlaskgvkvkiiapeeerkysaWiGGSiLAslgtfqqlwvs 390
                 es          gi+  ++++i +cdvd+r++L+ niv++GG++++pg+++R++ke+++la++++k+kiiap+ erkys+WiGGSiLAsl+tfqq+wvs
  EEA18960.1 270 ESG---------GIHVTTYNSIIKCDVDVRKDLYGNIVMSGGTTMYPGISDRMQKEITALAPSSMKIKIIAPP-ERKYSVWIGGSILASLSTFQQMWVS 358
                 ***.........*************************************************************.************************* PP

       Actin 391 kqEYeEqGssvverkck 407
                 kqEY+E+G+s+v+rkc+
  EEA18960.1 359 KQEYDESGPSIVHRKCF 375
                 ****************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (375 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       400  (0.0223102); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 2480.41
//
Query:       EEA18961.1  [L=375]
Description: actin Act1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.7e-150  501.2   0.0   6.1e-150  499.3   0.0    1.7  1  Actin     Actin


Domain annotation for each model (and alignments):
>> Actin  Actin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  499.3   0.0  3.4e-154  6.1e-150       2     407 .]       3     375 .]       2     375 .] 0.98

  Alignments for each domain:
  == domain 1  score: 499.3 bits;  conditional E-value: 3.4e-154
       Actin   2 devsavVlDnGssttraGyagedaPkavipslvgkprgrkvea.....klyvgdealtkrpelevrspvedGvvedwdaveelwehvlkeelkvdpeeh 95 
                 +ev a+V+DnGs++++aG+ag+daP+av+ps+vg+pr++  +      + yvgdea++kr+ l++r+p+e+Gvv++wd++e++w+h++++el+v peeh
  EEA18961.1   3 EEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHHGIMIgmgqkDSYVGDEAQSKRGILTLRYPIEHGVVTNWDDMEKIWHHTFYNELRVAPEEH 101
                 689************************************9887999999************************************************** PP

       Actin  96 pllltepplnppkqrekalEivfEkfkvpalylaksavlsafasgkstglvvDsGasvtsvvpVldGyvLkkairrsdlgGkaLteqlkellssknvev 194
                 p+llte+p np+++rek+++ivfE+f+ pa+y++ +avls++asg++tg+v+DsG++vt+vvp+++G++L +ai r+d++G++Lt++l+++l ++    
  EEA18961.1 102 PVLLTEAPINPKSNREKMTQIVFETFNAPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTHVVPIYEGFALPHAISRVDMAGRDLTDYLMKILAER---- 196
                 **********************************************************************************************8.... PP

       Actin 195 tprylikkkkvveaessaekeelekltesyktleeeevleeiKesvcevsedpeg..deeksssspeksYeLPDgseiklgeeRfkvpEiLFdpsligs 291
                                           ++s++t++e+e++++iKe++c+v+ d+e+  +++++sss eksYeLPDg++i++g+eRf++pE+LF+ps ig 
  EEA18961.1 197 --------------------------GYSFSTTAEREIVRDIKEKLCYVALDFEQeiQTASQSSSLEKSYELPDGQVITIGNERFRAPEALFQPSVIGL 269
                 ..........................9***************************977777778************************************ PP

       Actin 292 esaleeekskllgiselivaainacdvdlrpeLlanivvtGGnsllpglteRlekelaqlaskgvkvkiiapeeerkysaWiGGSiLAslgtfqqlwvs 390
                 es          gi+  ++++i +cdvd+r++L+ niv++GG++++pg+++R++ke+++la++++k+kiiap+ erkys+WiGGSiLAsl+tfqq+wvs
  EEA18961.1 270 ESG---------GIHVTTYNSIIKCDVDVRKDLYGNIVMSGGTTMYPGISDRMQKEITALAPSSMKIKIIAPP-ERKYSVWIGGSILASLSTFQQMWVS 358
                 ***.........*************************************************************.************************* PP

       Actin 391 kqEYeEqGssvverkck 407
                 kqEY+E+G+s+v+rkc+
  EEA18961.1 359 KQEYDESGPSIVHRKCF 375
                 ****************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (375 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       400  (0.0223102); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.24s 00:00:00.75 Elapsed: 00:00:00.41
# Mc/sec: 2748.96
//
Query:       EEA18962.1  [L=80]
Description: hypothetical protein PMAA_012320 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (80 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       247  (0.0137766); expected 358.6 (0.02)
Passed bias filter:                      222  (0.0123822); expected 358.6 (0.02)
Passed Vit filter:                         9  (0.00050198); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.35u 0.22s 00:00:00.56 Elapsed: 00:00:00.37
# Mc/sec: 642.99
//
Query:       EEA18963.1  [L=216]
Description: Hsp70 nucleotide exchange factor (Fes1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.8e-29  102.4   4.0    3.3e-29  101.6   3.0    1.9  2  Fes1             Nucleotide exchange factor Fes1
    4.1e-09   36.7   0.5    7.9e-08   32.6   0.1    2.5  2  HEAT_EZ          HEAT-like repeat
    2.1e-08   33.7   0.1     0.0011   19.0   0.0    3.0  3  HEAT             HEAT repeat
    2.1e-07   30.7   0.1     0.0097   15.9   0.0    2.8  3  Arm              Armadillo/beta-catenin-like repeat
    4.7e-07   30.1   0.2    1.3e-06   28.7   0.0    1.9  2  HEAT_2           HEAT repeats
  ------ inclusion threshold ------
      0.024   14.7   0.0       0.77    9.9   0.0    1.9  2  V-ATPase_H_C     V-ATPase subunit H
      0.071   12.4   0.0      0.096   12.0   0.0    1.2  1  V-ATPase_H_N     V-ATPase subunit H
       0.12   12.0   0.0       0.55    9.8   0.0    2.0  1  AIRC             AIR carboxylase
       0.14   11.6   0.0       0.21   11.1   0.0    1.3  1  Tospo_nucleocap  Tospovirus nucleocapsid protein


Domain annotation for each model (and alignments):
>> Fes1  Nucleotide exchange factor Fes1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.6   3.0   1.6e-32   3.3e-29       1      93 []       5      96 ..       5      96 .. 0.87
   2 ?   -1.6   0.0       2.6   5.1e+03      52      84 ..     115     148 ..     105     150 .. 0.52

  Alignments for each domain:
  == domain 1  score: 101.6 bits;  conditional E-value: 1.6e-32
        Fes1  1 lneLLkWsienstaedasaseqeaesaaeaakaskekldpeildallggpsdaelmkeamevledeevtlenkliAldnleqlieslDnAnnL 93
                lneLLkWs+ens+a+ +s ++ +++ ++  ++++ + l++ +l+al+ggpsda+lmke+m++l +eev+lenkl A+dn+eql+e++DnAnn+
  EEA18963.1  5 LNELLKWSVENSEASRQSIANINDDPTSV-PPPTLNGLNEAALRALMGGPSDADLMKESMAALLSEEVDLENKLVAFDNFEQLVENIDNANNM 96
                89*********877777655544444444.44455*********************************************************8 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 2.6
        Fes1  52 daelmke.amevledeevtlenkliAldnleqli 84 
                 d  +m + ++ ++ +++++ ++kl  l+ l  l+
  EEA18963.1 115 DMRRMAAsCIGTAVQNNEKGQDKLLVLNVLPTLV 148
                 3333433123333344667777777777666665 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.1       0.2   4.1e+02       4      33 ..      42      66 ..      40      71 .. 0.61
   2 !   32.6   0.1     4e-11   7.9e-08       3      53 ..     116     168 ..     105     169 .. 0.93

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.2
     HEAT_EZ  4 RraAawaLGrlaggepellqplvpeilpaL 33
                 +aA++aL+     +++ +++l +e ++aL
  EEA18963.1 42 NEAALRALM-----GGPSDADLMKESMAAL 66
                689999996.....3344444444555555 PP

  == domain 2  score: 32.6 bits;  conditional E-value: 4e-11
     HEAT_EZ   3 vRraAawaLGr.laggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53 
                  Rr Aa+++G+ + ++e+ ++++lv  +lp L++l ++d+d +VR ++++aL+
  EEA18963.1 116 MRRMAASCIGTaVQNNEKGQDKLLVLNVLPTLVSLATTDPDpKVRRKCVYALS 168
                 59*********999999*******************666666**********8 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0       6.2   1.2e+04      19      30 ..      78      89 ..      77      90 .. 0.79
   2 !   11.5   0.0   0.00014      0.29       4      28 ..     104     128 ..     101     130 .. 0.88
   3 !   19.0   0.0   5.7e-07    0.0011       1      25 [.     143     168 ..     143     174 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 6.2
                HHHHHHHHHHHC CS
        HEAT 19 aAakaLgalaev 30
                 A+ ++ +l+e+
  EEA18963.1 78 VAFDNFEQLVEN 89
                588899999986 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 0.00014
                 HHHHHHT-SSHHHHHHHHHHHHHHH CS
        HEAT   4 lllkllsDpspeVReaAakaLgala 28 
                 +l+ ll++++++ R++Aa ++g+ +
  EEA18963.1 104 PLVGLLQHKEADMRRMAASCIGTAV 128
                 58899*****************866 PP

  == domain 3  score: 19.0 bits;  conditional E-value: 5.7e-07
                 HHHHHHHHH.T-SSHHHHHHHHHHHH CS
        HEAT   1 llPlllkll.sDpspeVReaAakaLg 25 
                 +lP+l++l  +Dp+p+VR+ +++aL 
  EEA18963.1 143 VLPTLVSLAtTDPDPKVRRKCVYALS 168
                 69******88**************97 PP

>> Arm  Armadillo/beta-catenin-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0         6   1.2e+04      17      20 ..      46      49 ..      43      67 .. 0.59
   2 !   11.8   0.0   9.6e-05      0.19      16      37 ..     104     125 ..     103     126 .. 0.95
   3 !   15.9   0.0   4.9e-06    0.0097       5      37 ..     135     168 ..     131     171 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 6
                HHHH CS
         Arm 17 LvrL 20
                L +L
  EEA18963.1 46 LRAL 49
                3344 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 9.6e-05
                 HHHHHTTTSSHHHHHHHHHHHH CS
         Arm  16 pLvrLLssedeevqeeAawALs 37 
                 pLv LL+++  ++++ Aa++++
  EEA18963.1 104 PLVGLLQHKEADMRRMAASCIG 125
                 8******************996 PP

  == domain 3  score: 15.9 bits;  conditional E-value: 4.9e-06
                 HHHHHHTTHHHHHHHHTT.TSSHHHHHHHHHHHH CS
         Arm   5 kdavieaGavppLvrLLs.sedeevqeeAawALs 37 
                  d +  ++++p Lv+L + ++d++v++ ++ ALs
  EEA18963.1 135 QDKLLVLNVLPTLVSLATtDPDPKVRRKCVYALS 168
                 56667799************************98 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       3.7   7.3e+03      66      76 ..      45      55 ..      42      68 .. 0.50
   2 !   28.7   0.0   6.3e-10   1.3e-06       4      67 ..     105     185 ..     103     206 .. 0.74

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 3.7
      HEAT_2 66 aLkellddddd 76
                aL++l+  ++d
  EEA18963.1 45 ALRALMGGPSD 55
                34444444444 PP

  == domain 2  score: 28.7 bits;  conditional E-value: 6.3e-10
      HEAT_2   4 LlqalendpdpevrraairaLg...rignp.........ealpaLvell.ededpavRraaaeaLg.aigd.....pealpaL 67 
                 L+ +l ++++ + rr+a+ ++g   + +n+          +lp+Lv+l+ +d+dp vRr  + aL+ ai++     +e+l++L
  EEA18963.1 105 LVGLL-QHKEADMRRMAASCIGtavQ-NNEkgqdkllvlNVLPTLVSLAtTDPDPKVRRKCVYALSsAIRNfqpnmDEVLSHL 185
                 66667.89**************7641.33445556666677********99**************755542221225555555 PP

>> V-ATPase_H_C  V-ATPase subunit H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0   0.00039      0.77      46     116 ..      62     131 ..      54     132 .. 0.86
   2 ?    9.8   0.0   0.00042      0.84      42     114 ..     100     172 ..      88     174 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00039
  V-ATPase_H_C  46 kLiklleeskdktvlavalnDigelvkllpegkkvleklkaKekimellehedeevkyeALkavqkllvqn 116
                   ++++ll+e+ d ++  va  + ++lv+++++ ++ +e l+  + ++ ll+h+++++++ A  ++ + +++n
    EEA18963.1  62 SMAALLSEEVDLENKLVAFDNFEQLVENIDNANN-MEPLGLWTPLVGLLQHKEADMRRMAASCIGTAVQNN 131
                   4677787777889999************888765.79***************************9998875 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00042
  V-ATPase_H_C  42 kllkkLiklleeskdktvlavalnDigelvkllpegkkvleklkaKekimellehe.deevkyeALkavqkllv 114
                    l   L+ ll ++k+  +  +a++ ig  v++ ++g++ l  l++  ++++l +++ d++v+++   a+++ + 
    EEA18963.1 100 GLWTPLVGLL-QHKEADMRRMAASCIGTAVQNNEKGQDKLLVLNVLPTLVSLATTDpDPKVRRKCVYALSSAIR 172
                   5666789999.478889999*************************999999988555*******9999998775 PP

>> V-ATPase_H_N  V-ATPase subunit H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   4.8e-05     0.096      89     170 ..      82     164 ..      65     179 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 4.8e-05
  V-ATPase_H_N  89 srvelflslakkeeqd...pwkpflkllnrqddfivllalrllakllvqgkkksnklv.esaLnrllqlLssqlssstnevieiav 170
                   ++++l++++ + ++ +   +w p++ ll+++++ + ++a+  + + +  ++k + kl   ++L++l++l ++    ++ +v   +v
    EEA18963.1  82 NFEQLVENIDNANNMEplgLWTPLVGLLQHKEADMRRMAASCIGTAVQNNEKGQDKLLvLNVLPTLVSLATTD---PDPKVRRKCV 164
                   5778888888877777888*************************99999888888855677777777775553...3334444444 PP

>> AIRC  AIR carboxylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0   0.00028      0.55       5     111 ..      49     153 ..      45     188 .. 0.67

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00028
                 EESSGGGHHHHHHHHHHHHHTT-EEEEEE--TTTSHHHHHHHHHHCHTTT.EEEEEEEEES....S--HHHHHHHHSSS-EEEEEE--STTCCHHHHHH CS
        AIRC   5 imGSdsDlevmkkaaeilkelgveyevrvvSahrtpeelleyaeeaeerg.lkviIagAGg....aahLpgvvaslttlPVigvPvkskalkgldsllS 98 
                 +mG  sD + mk+ +++l + +v++e + v      + ++++ ++a++++ l       G     +a++  + as      ig  v++ + kg d+ll 
  EEA18963.1  49 LMGGPSDADLMKESMAALLSEEVDLENKLVAFDNFEQLVENI-DNANNMEpLGLWTPLVGLlqhkEADMRRMAAS-----CIGTAVQN-NEKGQDKLLV 140
                 7*************************9998655554444444.44444332555555555411123334444333.....46666666.5566666666 PP

                 HHT--TTS--EE- CS
        AIRC  99 ivqmPsgvpvatv 111
                    +P+ v++at 
  EEA18963.1 141 LNVLPTLVSLATT 153
                 6666666666665 PP

>> Tospo_nucleocap  Tospovirus nucleocapsid protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0    0.0001      0.21       3      51 ..      55      99 ..      53     127 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.0001
  Tospo_nucleocap  3 kvkltkesivalltqgkdlefeedqnlvafnfktfclenidqikkmsvi 51
                        l kes+ all++  dle    ++lvaf+     +enid+ ++m  +
       EEA18963.1 55 DADLMKESMAALLSEEVDLE----NKLVAFDNFEQLVENIDNANNMEPL 99
                     56799*********999997....57****8777889*****9999765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (216 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       416  (0.0232026); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1480.31
//
Query:       EEA18964.1  [L=172]
Description: UPF0220 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.6e-72  240.7   2.7    6.3e-72  240.5   2.7    1.0  1  UPF0220          Uncharacterised protein family (UPF0220)
  ------ inclusion threshold ------
       0.17   11.4   0.5       0.48    9.9   0.0    2.0  2  ATP1G1_PLM_MAT8  ATP1G1/PLM/MAT8 family


Domain annotation for each model (and alignments):
>> UPF0220  Uncharacterised protein family (UPF0220)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  240.5   2.7     7e-76   6.3e-72       2     166 .]       4     166 ..       3     166 .. 0.99

  Alignments for each domain:
  == domain 1  score: 240.5 bits;  conditional E-value: 7e-76
     UPF0220   2 edrlfrfrkpklklensakrravgvylaGaLfalgfwlliDaaivskka.nasdvhvtfvdwipgicstlgmlivnsieksrlsgdslgqsgssvawka 99 
                 e+rl+rf+kp  ++ n++++r++gvy++GaLf+lgf++liDa+++s +  n+s+vhv+fvdw+pgics lgml++nsieksrls+ds+++sgs+vawka
  EEA18964.1   4 ENRLWRFQKP--EWLNNSTLRTTGVYVSGALFSLGFFFLIDASAFSASPrNGSNVHVKFVDWVPGICSALGMLVINSIEKSRLSADSFSYSGSGVAWKA 100
                 689******9..899*********************************99************************************************* PP

     UPF0220 100 rvvLflGfallagglagslvvlilkYvvkdytefptlgmGvanvlqNllimlssvvlwvsqnvedeY 166
                 r+vLflGfallagglags++vl+lkYv+kdy +++tl++G+anv++N l+mlss+vlw+sqn+ed+Y
  EEA18964.1 101 RFVLFLGFALLAGGLAGSVTVLVLKYVMKDY-PLQTLYFGIANVIANGLVMLSSIVLWISQNIEDDY 166
                 *******************************.89********************************9 PP

>> ATP1G1_PLM_MAT8  ATP1G1/PLM/MAT8 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0   5.3e-05      0.48      11      32 ..      19      40 ..      17      45 .. 0.91
   2 ?   -3.0   0.1      0.57   5.1e+03      23      34 ..      67      78 ..      65      80 .. 0.69

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 5.3e-05
                     CCHHHHHHHHHHHHHHHHHHHH CS
  ATP1G1_PLM_MAT8 11 esLrlgGLifAglLfivGilii 32
                      +Lr+ G+ ++g Lf +G+  +
       EEA18964.1 19 STLRTTGVYVSGALFSLGFFFL 40
                     59****************9876 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.57
                     HHHHHHHHHHHC CS
  ATP1G1_PLM_MAT8 23 lLfivGiliilS 34
                     +  ++G+l+i S
       EEA18964.1 67 ICSALGMLVINS 78
                     555678888866 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (172 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       448  (0.0249875); expected 358.6 (0.02)
Passed bias filter:                      242  (0.0134977); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.44
# Mc/sec: 1179.89
//
Query:       EEA18965.1  [L=264]
Description: proteasome component Pre5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.5e-48  164.8   0.1      2e-48  164.4   0.1    1.2  1  Proteasome      Proteasome subunit
      3e-12   46.0   0.3      5e-12   45.3   0.3    1.4  1  Proteasome_A_N  Proteasome subunit A N-terminal signature


Domain annotation for each model (and alignments):
>> Proteasome  Proteasome subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  164.4   0.1   2.2e-52     2e-48       1     190 []      29     215 ..      29     215 .. 0.96

  Alignments for each domain:
  == domain 1  score: 164.4 bits;  conditional E-value: 2.2e-52
                 HHHS-EEEEEEETTEEEEEEEEEEEETTEEEESSSSTSEEEEETTEEEEEEESHHHHHHHHHHHHHHHHHHHHHHSSGTCHHHHHHHHHHHHHHHHHHC CS
  Proteasome   1 vkkGttvvGikgkdgvvlaadkratagskllskstveKifkiddhigvafaGlaaDartlvrraraeaqlyrlrygrpipverlvarvaaklqaytqrs 99 
                 vk+G+ vvG+ +k ++vl++ kr+    +l s+ + +K+++id h+g+a+aGl +Dar+l ++++++    r++ygr ip++r+v ++ +++q +tq++
  EEA18965.1  29 VKQGSVVVGLVSKTHAVLVGLKRNA--EEL-SSYQ-KKVIEIDTHMGIAIAGLSSDARVLSNFMKQQSLGSRMTYGRAIPLDRIVTQIGDRAQTNTQHY 123
                 799**********************..888.9997.*************************************************************** PP

                 TTTTTSEEEEEEEEETTTEEEEEEEETTSEEEEESSEEEESTTHHHHHHHHHHHH..STTBSHHHHHHHHHHHHHHHHHHBT.TSCSSEEEEEE CS
  Proteasome 100 grrpfgvslliagvdeeggpeLyqidpsGsyieekdavaiGsgseaaktalekey..kedltleeavelavkalkealerdk.lsgknievavi 190
                 g+rp+gv+ll+agvd+ g p+L++++psG   e   a+aiG +s++a+t+le+++  + d+++ee++ + +kal+e+l +dk l+ +n +v+v+
  EEA18965.1 124 GKRPYGVGLLVAGVDDAG-PHLFEFQPSGMTQEM-LACAIGARSQMARTYLERNLaeFADCSREELINHGLKALRETLSQDKeLTIDNTTVGVV 215
                 ***************887.***************.6********************9*********************65544******99986 PP

>> Proteasome_A_N  Proteasome subunit A N-terminal signature
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.3   0.3   5.6e-16     5e-12       1      23 []       6      28 ..       6      28 .. 0.99

  Alignments for each domain:
  == domain 1  score: 45.3 bits;  conditional E-value: 5.6e-16
  Proteasome_A_N  1 YDrslttFSPdGRLfQVEYAmkA 23
                    YD++  tFSP+GR+fQVEYA++A
      EEA18965.1  6 YDNDSVTFSPQGRIFQVEYAQEA 28
                    9*********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (264 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       590  (0.0329076); expected 358.6 (0.02)
Passed bias filter:                      513  (0.0286129); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 1882.09
//
Query:       EEA18966.1  [L=195]
Description: proteasome component Pre5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    3.5e-37  127.7   0.0    4.7e-37  127.3   0.0    1.2  1  Proteasome  Proteasome subunit


Domain annotation for each model (and alignments):
>> Proteasome  Proteasome subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.3   0.0   2.6e-41   4.7e-37      46     190 .]       1     146 [.       1     146 [. 0.96

  Alignments for each domain:
  == domain 1  score: 127.3 bits;  conditional E-value: 2.6e-41
                 EEEEEEESHHHHHHHHHHHHHHHHHHHHHHSSGTCHHHHHHHHHHHHHHHHHHCTTTTTSEEEEEEEEETTTEEEEEEEETTSEEEEESSEEEESTTHH CS
  Proteasome  46 igvafaGlaaDartlvrraraeaqlyrlrygrpipverlvarvaaklqaytqrsgrrpfgvslliagvdeeggpeLyqidpsGsyieekdavaiGsgse 144
                 +g+a+aGl +Dar+l ++++++    r++ygr ip++r+v ++ +++q +tq++g+rp+gv+ll+agvd+ g p+L++++psG   e   a+aiG +s+
  EEA18966.1   1 MGIAIAGLSSDARVLSNFMKQQSLGSRMTYGRAIPLDRIVTQIGDRAQTNTQHYGKRPYGVGLLVAGVDDAG-PHLFEFQPSGMTQEM-LACAIGARSQ 97 
                 699******************************************************************887.***************.6********* PP

                 HHHHHHHHHH..STTBSHHHHHHHHHHHHHHHHHHBT.TSCSSEEEEEE CS
  Proteasome 145 aaktalekey..kedltleeavelavkalkealerdk.lsgknievavi 190
                 +a+t+le+++  + d+++ee++ + +kal+e+l +dk l+ +n +v+v+
  EEA18966.1  98 MARTYLERNLaeFADCSREELINHGLKALRETLSQDKeLTIDNTTVGVV 146
                 ***********9*********************65544******99986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (195 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       386  (0.0215294); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.43
# Mc/sec: 1376.22
//
Query:       EEA18967.1  [L=251]
Description: lysine decarboxylase-like protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.4e-27   94.2   0.1    1.5e-26   93.1   0.1    1.6  1  Lysine_decarbox  Possible lysine decarboxylase
     0.0055   16.3   1.0      0.051   13.2   0.1    2.2  2  LDcluster4       SLOG cluster4 family
  ------ inclusion threshold ------
       0.21   11.2   1.7        2.9    7.5   0.2    2.4  3  DAGK_cat         Diacylglycerol kinase catalytic domain


Domain annotation for each model (and alignments):
>> Lysine_decarbox  Possible lysine decarboxylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.1   0.1   2.5e-30   1.5e-26       1     131 [.      56     233 ..      56     234 .. 0.90

  Alignments for each domain:
  == domain 1  score: 93.1 bits;  conditional E-value: 2.5e-30
                      HHHHHHHHHHTTS-..EEEEEECCHHHHHCC........................................TTT-SEEEEESSHHHHHHHHHHH CS
  Lysine_decarbox   1 meavakgaleaggr..viGiipkillaeeap........................................neevnelvivedmeeRkealvel 52 
                      m+ +a+  ++++g+  v+Giipk+l++ e                                          + e++ ++iv+dm++Rk+ ++ +
       EEA18967.1  56 MGQIARELVRLSGPeaVHGIIPKALIKIEPGyqqlqdgkpatdgkpniktqegagktaervvkadkrteiiEAEYGITTIVPDMHTRKRLMATK 149
                      777788888777777799999999999776679999999999999999999999999999999999999999999999**************97 PP

                      ......ESEEEE-S-SHHHHHHHHHHHHHHHTTSS-S.EEEEEEGGGCCHHHHHHHHHHHHTTSS-GGGGGCEEEESSHHHHHHH CS
  Lysine_decarbox  53 ......adafvilPGGiGTleElleiltliqlgkhqkvPiillnpkgyydkllefletlveegtisekareliivvddpeevlek 131
                            + +fv+++GG+GT+eE++e+ t+ qlg+h+   i+lln++gy+d +l++++++v+eg+is+++  +++ v+++++vl k
       EEA18967.1 150 vleggpGSGFVAMAGGFGTIEEVMEMTTWNQLGIHKV-GIVLLNTEGYWDGVLAWIKNAVKEGFISSANGGILVDVHEVKDVLPK 233
                      55555579***************************99.*********************************99999999998866 PP

>> LDcluster4  SLOG cluster4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.2   0.1   8.5e-06     0.051       3      51 ..      13      62 ..      11      82 .. 0.79
   2 ?    1.6   0.1     0.031   1.9e+02     100     114 ..     159     173 ..     154     198 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 8.5e-06
  LDcluster4  3 kigVm.GsaeteakeealelaeelGrliAkegavlltGgrt.GvmeaaskG 51
                 ++V+ Gs e + ++ +++ a++l+r+  ++++ l+ Gg t G+m   ++ 
  EEA18967.1 13 VVCVFcGSVE-GNNPVHMQAAKDLARAFHEQNVQLVYGGGTmGIMGQIARE 62
                6788526666.47777899*******************9999***887775 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.031
  LDcluster4 100 viaiggrsGTlsEia 114
                  +a+ g+ GT++E++
  EEA18967.1 159 FVAMAGGFGTIEEVM 173
                 5899*********86 PP

>> DAGK_cat  Diacylglycerol kinase catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0     0.017     1e+02      41      89 ..      29      77 ..      15      78 .. 0.78
   2 ?    7.5   0.2   0.00049       2.9      11      86 ..     110     187 ..     104     193 .. 0.68
   3 ?   -3.4   0.0       1.2   6.9e+03      65      77 ..     198     210 ..     198     216 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.017
                TTHHHHHHHHHHHCC-SEEEEEESHHHHHHHHHHHCTHHCTTSEEEEEE CS
    DAGK_cat 41 pgdakelakeakeegvdlivvaGGDGtvsevlnglleelatkpplgiiP 89
                 + ak+la+   e++v+l+   G  G++++++  l++  + +   giiP
  EEA18967.1 29 MQAAKDLARAFHEQNVQLVYGGGTMGIMGQIARELVRLSGPEAVHGIIP 77
                566999*******888877766667999999999999666666667777 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.00049
                 TTTTHHHHHHHCHHHHHHCTCEEEEEE--STTHHHHHHHHHHHC..C-SEEEEEESHHHHHHHHHHHCTHHCTTSEEE CS
    DAGK_cat  11 Gkgkgekllrkvrelleeagvelelieteepgdakelakeakee..gvdlivvaGGDGtvsevlnglleelatkpplg 86 
                 Gk++ + +    r  + ea++ +++i  +     + +a+++ e   g  ++ +aGG Gt++ev++   +++    ++g
  EEA18967.1 110 GKTAERVVKADKRTEIIEAEYGITTIVPDMHTRKRLMATKVLEGgpGSGFVAMAGGFGTIEEVMEMTTWNQLGIHKVG 187
                 44444444455555566677777777777777777778888887344599*************998777444445555 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 1.2
                 HHHHHHHHHHHCT CS
    DAGK_cat  65 DGtvsevlnglle 77 
                 DG++ ++ n++ e
  EEA18967.1 198 DGVLAWIKNAVKE 210
                 9999999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (251 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       534  (0.0297841); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.40
# Mc/sec: 1862.69
//
Query:       EEA18968.1  [L=309]
Description: RNA polymerase II transcription mediator complex subunit (Med6), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.5e-38  130.4   0.1    5.8e-38  129.7   0.1    1.3  1  Med6      MED6 mediator sub complex component


Domain annotation for each model (and alignments):
>> Med6  MED6 mediator sub complex component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  129.7   0.1   3.2e-42   5.8e-38       2     132 ..      13     172 ..      12     173 .. 0.90

  Alignments for each domain:
  == domain 1  score: 129.7 bits;  conditional E-value: 3.2e-42
        Med6   2 qwkspewlqal..gLtennvldYFaespFydktsnNevlkmqrqfnqaaeeal.........LkkmkGleyvla.............hvqep....dlf 72 
                  w+sp+++q++   L++nn+l YFaespF+d tsnN++l+ q+++n+a+++ l         Lk+m+Gle+++a                      +++
  EEA18968.1  13 FWRSPQHVQMMggFLHSNNILFYFAESPFFDATSNNASLTIQATYNEAFRHFLetreafegrLKTMQGLEFMVAydplqaaaqsdtqF---AhepsNIW 108
                 6**********9889**********************************9997888999999************77776665555552...05557*** PP

        Med6  73 virkqerksa....tevtvlaaYyiiggniYqapslysvvqsrllsalsslskalkelsslakf 132
                 +irkq r+++    ++v vl++Yyi+g+++Y+ap + sv+ +r+lsa++sl+k+++ +s+l+ f
  EEA18968.1 109 IIRKQMRQKRpgmeDDVVVLSTYYIVGDSVYMAPAVSSVIGNRILSAVTSLTKLMNVASRLPIF 172
                 *********977777*****************************************99998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       697  (0.0388756); expected 358.6 (0.02)
Passed bias filter:                      491  (0.0273858); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.23s 00:00:00.72 Elapsed: 00:00:00.40
# Mc/sec: 2306.29
//
Query:       EEA18969.1  [L=129]
Description: Vacuolar protein sorting 55 superfamily [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-43  147.9   7.3    1.2e-43  147.7   7.3    1.0  1  Vps55     Vacuolar protein sorting 55


Domain annotation for each model (and alignments):
>> Vps55  Vacuolar protein sorting 55
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  147.7   7.3   6.9e-48   1.2e-43       1     117 []       9     127 ..       9     127 .. 0.95

  Alignments for each domain:
  == domain 1  score: 147.7 bits;  conditional E-value: 6.9e-48
       Vps55   1 iillsfvlaiGfllvilsCalyknwwpLlvvlfyllaplPnliakrlsssed..seessalkdlakFltgvlvvsgiaLpivLahagiikwgalilsla 97 
                 ii+lsf+laiGfllvils+a++++++pLlvv++y+laplPn+i++++ + +d  +++++a++d+++Fltg+lv++giaLp+vLah+g+i + a+++s++
  EEA18969.1   9 IIVLSFILAIGFLLVILSAAIWQQYLPLLVVATYVLAPLPNWICSHCGNPDDfiESSGNAIVDFGRFLTGFLVLMGIALPTVLAHCGYIGYPAMVMSIL 107
                 8*********************************************886665554799***************************************** PP

       Vps55  98 ggvviyltiivfflffkeee 117
                 gg++iy+tii+f+ ff+e+e
  EEA18969.1 108 GGLLIYGTIISFSTFFQEQE 127
                 ****************9975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (129 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1058  (0.0590105); expected 358.6 (0.02)
Passed bias filter:                      578  (0.0322383); expected 358.6 (0.02)
Passed Vit filter:                        73  (0.00407162); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.25s 00:00:00.65 Elapsed: 00:00:00.39
# Mc/sec: 981.28
//
Query:       EEA18970.1  [L=495]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.2e-14   52.4   0.0    8.4e-14   51.5   0.0    1.6  1  Sld7_C    Sld7 C-terminal domain


Domain annotation for each model (and alignments):
>> Sld7_C  Sld7 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.5   0.0   4.7e-18   8.4e-14       2      78 .]     359     482 ..     358     482 .. 0.96

  Alignments for each domain:
  == domain 1  score: 51.5 bits;  conditional E-value: 4.7e-18
      Sld7_C   2 eqnkealsklilagLRlrGlsqs..........................................eaeeaaekeeykelYhmtykaaeFAlRkelak.. 56 
                 ++nk+ +++ il+ +Rl+G +++                                          ++++  e++++k +Yh ty+aa+FAlR++l+   
  EEA18970.1 359 TRNKDLITRTILTCMRLYGYNRKanrstkpptvgtrepshepdayqressmmpeysnvpvgeeakQSSSVTEEDDFKAMYHATYRAATFALRHYLKVva 457
                 58**************************************************************9999***************************9999 PP

      Sld7_C  57 ...kklqikleklqdtVekLLklFv 78 
                     ++ ++ ++  ++++  Lk+F+
  EEA18970.1 458 vetLPPVLSKDTATNVIDGILKIFC 482
                 8877888889**************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (495 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       348  (0.0194099); expected 358.6 (0.02)
Passed bias filter:                      268  (0.0149478); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.34s 00:00:01.02 Elapsed: 00:00:00.57
# Mc/sec: 2602.55
//
Query:       EEA18971.1  [L=220]
Description: endo-arabinanase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.2e-16   59.1   0.0    5.5e-16   58.7   0.0    1.1  1  Glyco_hydro_43  Glycosyl hydrolases family 43


Domain annotation for each model (and alignments):
>> Glyco_hydro_43  Glycosyl hydrolases family 43
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.7   0.0     3e-20   5.5e-16     118     288 .]      17     201 ..       7     201 .. 0.82

  Alignments for each domain:
  == domain 1  score: 58.7 bits;  conditional E-value: 3e-20
                     SSECEEEEEEE...TTSEEEEEEEEEHCCCSEEEEEEEEEETTTTEEEEEEEEEEECGCCTCTTBBEEEEEEEEETTEEEEEEE........... CS
  Glyco_hydro_43 118 ssgiDpslfed...ddGkkYlvwgqwdkreghseiylaeldddtlklkgektklikagtelkglkvtEGPhlykrdgyyYLlaa........... 198
                     s++iDps++ d   + G+++l +g+++++     i+ ++l+ d l++++ k  +++  +    + ++E+ ++ ++  +yYL+++           
      EEA18971.1  17 SNAIDPSVIADplcNSGRAWLTFGSYWSG-----IWQVPLSSDLLSVENAKSPNATHVAFNASFPAEEASFVSYKAPWYYLWYSkgyccgldidd 106
                     799********44445************8.....**************999666666668889*********************88877766554 PP

                     ..ESTSSTT.EEEEEEEESSTTSGGEEECTCCSEE.T.......BTTSTSEEEEEEEEEE-TTSSEEEEEEEESCCTTCCGTTSSEEEEEEEEEE CS
  Glyco_hydro_43 199 ..eggtgse.yavvvarsksllgPyewkkknpiltsr.......speepiqgpGHaslvetpdgewyivyhagrpegrglytlgRetllqrvewk 283
                       +   g + y+++v+rs ++ gPy +k++ ++ +         + + +++ pG  +++ +++g++++ yh+ +    g ++    +  + ++++
      EEA18971.1 107 lpTA--G-TeYSIQVGRSLDVSGPYLDKESVSLAEGGgsmiygsNHDGQVYAPGSIGVISSDSGKDVLYYHYLNL-SIGISERDAILGYNYLDYD 197
                     2222..3.249******************9999888799999989999************************999.4444444444444566666 PP

                     TTSEE CS
  Glyco_hydro_43 284 aDGwp 288
                      DGwp
      EEA18971.1 198 -DGWP 201
                     .7776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (220 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       205  (0.011434); expected 358.6 (0.02)
Passed bias filter:                      171  (0.00953762); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.35s 00:00:00.91 Elapsed: 00:00:00.55
# Mc/sec: 1203.72
//
Query:       EEA18972.1  [L=446]
Description: endo-1,4-beta-mannosidase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.4e-16   60.0   0.5    3.6e-16   59.4   0.5    1.2  1  Cellulase        Cellulase (glycosyl hydrolase family 5)
    1.4e-11   44.1   5.8    1.4e-11   44.1   5.8    2.3  2  CBM_1            Fungal cellulose binding domain
    1.2e-06   28.4   0.3    2.2e-06   27.5   0.3    1.3  1  DUF4038          Protein of unknown function (DUF4038)
    0.00016   20.9   0.1     0.0008   18.6   0.0    2.2  2  Glyco_hydro_2_C  Glycosyl hydrolases family 2, TIM barrel dom
      0.009   15.4   0.1      0.016   14.6   0.1    1.3  1  Glyco_hydro_42   Beta-galactosidase


Domain annotation for each model (and alignments):
>> Cellulase  Cellulase (glycosyl hydrolase family 5)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.4   0.5     1e-19   3.6e-16      24     278 ..     149     412 ..     116     414 .. 0.69

  Alignments for each domain:
  == domain 1  score: 59.4 bits;  conditional E-value: 1e-19
                 HHHHHHHHHHT-SEEEEEEE....CTGGTTSSTTT.GCTHHHHHHHHHHHHHHHHTT-EEEEEEESSTTT.............CSSSSTTTTHHH.... CS
   Cellulase  24 kalidevkdagfntvRlpvs....wgelvenapdy.kvdenslerveevvkyakenglyvildiHseegw.............ltkadgnssedt.... 100
                 ++ ++ ++ +gfn v    s    + +l++n+  + +++++ le+++ vv  a+++g++ i+   ++  w               ++       t    
  EEA18972.1 149 ASGMKILRVWGFNDVNTVPSpgtvYFQLLANGTATiNTGADGLEKLDYVVSSAEAHGIKLIIPFVNN--WsdyggmaayvtafGGSQ-------Ttwyt 238
                 3344444555555444444433332444444444369999**********************99986..533333344443322222.......12222 PP

                 ...HHHHHHHHHHHHHHHHTTTTTTEEEESSSS--STTCTCCTCHHHTTHHHHHHHHHHHHHHHHTTSSEEEEECHH..............HHTBHHHH CS
   Cellulase 101 ...aeeffkklwtqiAerykkndevvifelmNEPhgnntgaewtseeadevkayaeeaikaIRavgpnrliivegns..............wsgnldga 182
                    a+  ++++++++ +ry  ++ + ++el NEP++++ +       +  ++++a+++ + I++ ++n+++  + ++              +s+  + +
  EEA18972.1 239 ntaAQVAYQAYIKAVVSRYRTSPAIFAWELGNEPRCKGCN-------TSVLTDWAKTTSAYIKSLDANHMVTTGIEGfgldagsdgsypytYSEGTNFT 330
                 33366669999*************************6554.......578******************9998887775566666655554444433333 PP

                 HCT.SGSSSSTTEEEEEEEET.TTHHHTGCGSHSCTHHHHHHHHHHHHHHHHHHTTSEEEEEEEESSTTSSHHHHHHHHHHHHHHHHTTTEE.EEEEES CS
   Cellulase 183 vln.dPndsqdnliysvHfYg.psdfaqtefgkdltdktnlaqrledaakylvekgipviigEfGgsnadgdlakeeaekwldylkekgisw.iyWsln 278
                 +l   P    d  + ++H Y+  +  a           ++  ++++++ + + + g+p i++EfG+ ++d+  + +ea   ++ l+ kgi+  ++W+++
  EEA18972.1 331 ALLsIP----DIDFGTIHLYPnSWGEA----------LSWGSSWVSTHGAACASIGKPCILEEFGA-TSDQ--CANEAPWQATSLNTKGIGAdMFWQYG 412
                 333466....66899******444544..........45669***********************8.6777..77777766999999999753778765 PP

>> CBM_1  Fungal cellulose binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.1   5.8     4e-15   1.4e-11       1      29 []      37      65 ..      37      65 .. 0.98
   2 ?   -2.9   0.1         2   7.1e+03      15      20 ..      67      72 ..      66      73 .. 0.78

  Alignments for each domain:
  == domain 1  score: 44.1 bits;  conditional E-value: 4e-15
       CBM_1  1 lwgQCGGigWtGpTtCvsgatCtyqNeyY 29
                ++gQCGG +++G+T+Cvsg++C  +N+yY
  EEA18972.1 37 AYGQCGGVNYSGSTACVSGYVCIFLNPYY 65
                5**************************** PP

  == domain 2  score: -2.9 bits;  conditional E-value: 2
       CBM_1 15 tCvsga 20
                +Cv+g+
  EEA18972.1 67 QCVPGT 72
                799996 PP

>> DUF4038  Protein of unknown function (DUF4038)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.5   0.3   6.2e-10   2.2e-06      12     176 ..     119     304 ..     110     324 .. 0.78

  Alignments for each domain:
  == domain 1  score: 27.5 bits;  conditional E-value: 6.2e-10
                 S-BE-EEEEE-TTHHHH--HHHHHHHHHHHHHTT--EEEEES-...SSSS-B-TTS-BS-SST....-S-T..HHHHHHHHHHHHHHTT-EEE..EESS CS
     DUF4038  12 gepffwlgDTaWelfhrltreeaekYlddRaeqGFnviqavvlaeldglkapnaygekplidndltkpnea..Yfdhvdkivelaaekgllia..lvpt 106
                  + +f+  +T W +f + ++++++  l+d a+ G  ++ +  +++++++++p  +   +l  n ++++n+     +++d++v+ a+++g+ +   +v  
  EEA18972.1 119 KTNYFVGTNTYWLAFLN-NKSDVDLVLSDIAASGMKILRVWGFNDVNTVPSPG-TVYFQLLANGTATINTGadGLEKLDYVVSSAEAHGIKLIipFVNN 215
                 467888899****9987.7899******************************4.444444444477777765699**************9777565666 PP

                 -.............HHHHHTT.....SS-HHHHHHHHHHHHHHHTT-S..EEEEEECCC-TT.......HHHHHHHHHHHHHH--SS-EEE CS
     DUF4038 107 w.............gdkvkegwgpenifnaekakeygkylvaRYkalp..iiWllggDrdgee......revwkaiaegikeldpyalitf 176
                 w             g + +++w  +n+  +  +++y+k +v+RY+  p    W lg + +++       ++  k+  ++ik+ld+++++t 
  EEA18972.1 216 WsdyggmaayvtafGGS-QTTW-YTNTAAQVAYQAYIKAVVSRYRTSPaiFAWELGNEPRCKGcntsvlTDWAKTTSAYIKSLDANHMVTT 304
                 65554443332222332.3455.455677777888*************644599**99999999987776667889999********9986 PP

>> Glyco_hydro_2_C  Glycosyl hydrolases family 2, TIM barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0      0.57     2e+03       3      24 ..     109     130 ..     108     167 .. 0.70
   2 !   18.6   0.0   2.2e-07    0.0008     101     151 ..     237     288 ..     200     436 .. 0.70

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.57
                      EETTEEEETTEEE-EEEEEE-S CS
  Glyco_hydro_2_C   3 vkdkllliNgkrllfkGvnrHe 24 
                      v++ +++i gk  +f G n   
       EEA18972.1 109 VNGLNFTIDGKTNYFVGTNTYW 130
                      6677899999999999999764 PP

  == domain 2  score: 18.6 bits;  conditional E-value: 2.2e-07
                      TTSGGGHHHHHHHHHHHHHHHTT-TTEEEEEEEESS.CHHHHHHHHHHHHHH CS
  Glyco_hydro_2_C 101 adnpewlkavldrieelverdkNHpsviiWSlgNEs.gagedikalaelikk 151
                        n   + a+   i+ +v+r +  p++  W lgNE+ + g++ + l++++k 
       EEA18972.1 237 YTNTAAQVAYQAYIKAVVSRYRTSPAIFAWELGNEPrCKGCNTSVLTDWAKT 288
                      45777889999999**********************9788887777665543 PP

>> Glyco_hydro_42  Beta-galactosidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.1   4.4e-06     0.016      94     144 ..     228     278 ..     222     304 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 4.4e-06
                     -SSSS----TT-HHHHHHHHHHHHHHHHHHTT-TTEEEEE-SSSTTTTS-- CS
  Glyco_hydro_42  94 kfgsrqhiclsspvyrekvakivealaerYkdhpavilwhidnEygchecy 144
                      fg+ q + +++++ + + ++ ++a+  rY++ pa+ +w++ nE  c+ c 
      EEA18972.1 228 AFGGSQTTWYTNTAAQVAYQAYIKAVVSRYRTSPAIFAWELGNEPRCKGCN 278
                     67888889999999999999999*********************9996332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (446 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       752  (0.0419432); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.73u 0.35s 00:00:01.08 Elapsed: 00:00:00.55
# Mc/sec: 2438.50
//
Query:       EEA18973.1  [L=538]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-31  109.1  28.1    2.2e-31  109.1  28.1    1.7  1  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  109.1  28.1   1.2e-35   2.2e-31       2     335 ..      68     457 ..      67     476 .. 0.82

  Alignments for each domain:
  == domain 1  score: 109.1 bits;  conditional E-value: 1.2e-35
       MFS_1   2 llaaflsalarsi.lgpalpl.alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.sslw.lllvlrvlqG 96 
                 +++a+ s+l+ s+ +gpa+ + ++a ++gisp+ ++ l++   l+++++sl+l +l  ++Grr+v ll++++f+ g l+++ + ++ +  l+v+rv++G
  EEA18973.1  68 IICAIYSFLGNSAlTGPAVYIpIYAAEFGISPTKASGLVSYPNLAFGFGSLILVPLYLKIGRRPVTLLSMAFFVGG-LVGA-SqATTYeGLMVARVFCG 164
                 5666667766666488999888******************************************************.7777.44666669********* PP

       MFS_1  97 lgagalfpagaaliadwfpkeergraigllsagfslGailgpllgglla.sslgWravfyilaivsllafvlfllllpeepperkrkspkeee...... 188
                 +g+g+  ++ + l+ d+f   erg+ +g+++++  lG+  gpl +g+++   ++Wr+ fy++ +++   +v +++l+ e++ +r+ ++p++ +      
  EEA18973.1 165 FGSGVCESLPVQLVNDIFFLHERGKRLGYYTICLCLGS-TGPLYAGYMLaGGYSWRLFFYVVLAFASAILVAAFFLVEETNFKRPEPTPTQSSditdek 262
                 *************************************9.899999999978888999999988888887666555554444444444444444777779 PP

       MFS_1 189 ..................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllpl.ylqevlglsglllaglllal 252
                                                   ++ + + +++ +++++ + v+w++ +  +++++g +++ + +pl ++   +++s   ++++lla+
  EEA18973.1 263 lqgsahaesispaviparksylstlrpwssidpdARFFTTIWRS-FTYFCVPAVFWVITTFGIYIGLGAFSFNYIFPLkITAPPYNWS--HTNSGLLAI 358
                 9*********************9999999999999999999999.**********97777777777888889999999889*******..344447777 PP

       MFS_1 253 lalvgailallagrlsdr............lgrrrrlllallllllaalglallavtssavllll....vlvliGfglgfvfpsllalasdlappeeag 335
                 + +vg +lal ++  sdr              ++ rl + ll +l+  +gl+l+++t +  l+++    +++l  fg+ f+f+ +la+a+d++ ++ a 
  EEA18973.1 359 ATVVGYALALPFTSSSDRlaayltkrnggiREAEMRLGVLLLPMLIPPAGLILFGFTAERNLHWMgyfaGVALDQFGSYFYFTFVLAYAVDSYYANTAE 457
                 777777777788888888666665556666555************************888888885554555567799999999999999999544433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (538 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       713  (0.039768); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.30s 00:00:00.98 Elapsed: 00:00:00.51
# Mc/sec: 3181.42
//
Query:       EEA18974.1  [L=373]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0001   22.4   0.0         30    4.8   0.0    6.1  6  T2SSI     Type II secretion system (T2SS), protein I


Domain annotation for each model (and alignments):
>> T2SSI  Type II secretion system (T2SS), protein I
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0     0.016   2.9e+02      25      55 ..     102     132 ..      98     136 .. 0.88
   2 ?    1.7   0.0     0.016   2.9e+02      25      55 ..     138     168 ..     134     172 .. 0.88
   3 ?    1.4   0.0      0.02   3.7e+02      27      55 ..     215     243 ..     208     247 .. 0.87
   4 !    4.8   0.0    0.0017        30      25      55 ..     249     279 ..     244     283 .. 0.89
   5 ?    1.8   0.0     0.016   2.8e+02      25      55 ..     285     315 ..     280     319 .. 0.88
   6 ?    1.7   0.0     0.017     3e+02      25      55 ..     321     351 ..     318     355 .. 0.88

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.016
                 TTSEEEEEEEEETTEEEEEEEEEEE-SSTTE CS
       T2SSI  25 paigesegevemagrrWywrveveatadpgl 55 
                 p++++++ge  +a+r+++  ++ + +a p++
  EEA18974.1 102 PGSNSEHGESGFAKRQFEFSSRPSGAATPSF 132
                 788999*************999999988887 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.016
                 TTSEEEEEEEEETTEEEEEEEEEEE-SSTTE CS
       T2SSI  25 paigesegevemagrrWywrveveatadpgl 55 
                 p++++++ge  +a+r+++  ++ + +a p++
  EEA18974.1 138 PGSNSEHGESGFAKRQFEFSSRPSGAATPSF 168
                 788999*************999999988887 PP

  == domain 3  score: 1.4 bits;  conditional E-value: 0.02
                 SEEEEEEEEETTEEEEEEEEEEE-SSTTE CS
       T2SSI  27 igesegevemagrrWywrveveatadpgl 55 
                 +g+++ge  +a+r+++  ++ + +a p++
  EEA18974.1 215 SGSEHGESGFAKRQFEFSSRPSGAATPSF 243
                 6999*************999999988887 PP

  == domain 4  score: 4.8 bits;  conditional E-value: 0.0017
                 TTSEEEEEEEEETTEEEEEEEEEEE-SSTTE CS
       T2SSI  25 paigesegevemagrrWywrveveatadpgl 55 
                 p++g+++ge ++a+r+++  ++ + +a p++
  EEA18974.1 249 PGSGSEHGESSFAKRQFEFSSRPSGAATPSF 279
                 899****************999999988887 PP

  == domain 5  score: 1.8 bits;  conditional E-value: 0.016
                 TTSEEEEEEEEETTEEEEEEEEEEE-SSTTE CS
       T2SSI  25 paigesegevemagrrWywrveveatadpgl 55 
                 p++++++ge  +a+r+++  ++ + +a p++
  EEA18974.1 285 PGSNSEHGESGFAKRQFEFSSRPSGAATPSF 315
                 788999*************999999988887 PP

  == domain 6  score: 1.7 bits;  conditional E-value: 0.017
                 TTSEEEEEEEEETTEEEEEEEEEEE-SSTTE CS
       T2SSI  25 paigesegevemagrrWywrveveatadpgl 55 
                 p++++++ge  +a+r+++  ++ + +a p++
  EEA18974.1 321 PGSNSEHGESGFAKRQFEFSSRPSGAATPSF 351
                 788999*************999999988887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (373 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                        70  (0.00390429); expected 358.6 (0.02)
Passed bias filter:                       36  (0.00200792); expected 358.6 (0.02)
Passed Vit filter:                         7  (0.000390429); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.47
# Mc/sec: 2393.24
//
Query:       EEA18975.1  [L=582]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.1e-79  264.0   0.0    1.5e-78  263.3   0.0    1.3  1  HAD_SAK_1        HAD domain family 1 in Swiss Army Knife RNA 
  ------ inclusion threshold ------
       0.13   10.9   0.1       0.19   10.3   0.1    1.2  1  UDPGP            UTP--glucose-1-phosphate uridylyltransferase
       0.14   12.1   0.3        0.5   10.3   0.2    1.8  2  Ins_allergen_rp  Insect allergen related repeat, nitrile-spec


Domain annotation for each model (and alignments):
>> HAD_SAK_1  HAD domain family 1 in Swiss Army Knife RNA repair proteins
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  263.3   0.0   2.5e-82   1.5e-78       1     203 []      67     271 ..      67     271 .. 0.97

  Alignments for each domain:
  == domain 1  score: 263.3 bits;  conditional E-value: 2.5e-82
   HAD_SAK_1   1 SPlpnpqlwtkeligllqseevlknggWwsdpriLeesvkeslkaatgegv....erawegwWnekivelarlsikdkdtltvlLTGRkekkFselier 95 
                 SPlpnpqlw++++ig lq++e ++nggWw+d++iL         +atgeg+     raw+gwWne++v+l++ls+k+kd+ltvlLTGR e++F+++i+r
  EEA18975.1  67 SPLPNPQLWSGSTIGYLQTYEGFANGGWWHDQSIL---------SATGEGAdveeARAWAGWWNEQVVQLVELSMKQKDALTVLLTGRGEDNFTDIIKR 156
                 9**********************************.........667777777889******************************************* PP

   HAD_SAK_1  96 ileskklkfdavvLkkkvepsseefesTmeFKqafledlletyksleeitiYedrpkhvkkfkefleklnkkkk.......pikaeviqvaelskyldp 187
                 i++s++l+fd+v+Lk++v+p++++f sT++FKq+fle+l++ty+++eei++Yedr+khvk+f+ef++k+n++         pi+aevi++ae + +ldp
  EEA18975.1 157 IVASRNLEFDMVCLKPEVGPNGQQFPSTISFKQSFLESLISTYHQAEEIRVYEDRVKHVKAFREFFAKINDRYLqsqgdrkPITAEVIHIAEGTVHLDP 255
                 **********************************************************************9987899***999**************** PP

   HAD_SAK_1 188 ekEvklvqelinehnk 203
                 ++Ev++vq+++nehn+
  EEA18975.1 256 VTEVAEVQKMVNEHNR 271
                 ***************6 PP

>> UDPGP  UTP--glucose-1-phosphate uridylyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.1   3.2e-05      0.19     278     373 ..     153     254 ..     150     280 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 3.2e-05
       UDPGP 278 alkrlveekelkleiivnkktld.egek...viqleta.vgaaiksFkkavginVpRsrflpvkttsdlLlvksdlysleegslvlnpkrsf.ktvplv 370
                  +kr+v +++l+ +++  k ++  +g++    i+++++ + + i+ +++a  i+V  +r+  vk+ ++++    d+y  ++g  ++ +++ +  +  +v
  EEA18975.1 153 IIKRIVASRNLEFDMVCLKPEVGpNGQQfpsTISFKQSfLESLISTYHQAEEIRVYEDRVKHVKAFREFFAKINDRYLQSQGDRKPITAEVIhIAEGTV 251
                 699****************999989999999888887725689**********************************9999965543333321333344 PP

       UDPGP 371 kLg 373
                 +L+
  EEA18975.1 252 HLD 254
                 443 PP

>> Ins_allergen_rp  Insect allergen related repeat, nitrile-specifier detoxification
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0       0.3   1.8e+03     121     162 ..     122     163 ..     121     164 .. 0.89
   2 ?   10.3   0.2   8.3e-05       0.5      89     150 ..     169     231 ..     147     246 .. 0.77

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.3
  Ins_allergen_rp 121 dkivalieeklktskeFakfyealrsdefkklleklmkspev 162
                      +++v+l+e ++k++ ++  + +    d+f ++++++ +s+++
       EEA18975.1 122 EQVVQLVELSMKQKDALTVLLTGRGEDNFTDIIKRIVASRNL 163
                      688999999999999999999999999999999999999885 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 8.3e-05
  Ins_allergen_rp  89 elvpplvesaseskklggl.rgfvqdllavlPrdkivalieeklktskeFakfyealrsdefk 150
                      +l+p   ++ ++  ++ ++ ++f++ l +++ +++ +  +e+ +k  k+F++f+ ++++  ++
       EEA18975.1 169 CLKPEVGPNGQQFPSTISFkQSFLESLISTYHQAEEIRVYEDRVKHVKAFREFFAKINDRYLQ 231
                      444443334444444778889************************************987666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (582 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       469  (0.0261587); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.41
# Mc/sec: 4223.93
//
Query:       EEA18976.1  [L=361]
Description: RING finger domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.5e-09   37.3   4.4    4.1e-09   36.6   4.4    1.4  1  zf-RING_2    Ring finger domain
    4.5e-07   29.6   4.6      7e-07   29.0   4.6    1.3  1  zf-C3HC4_2   Zinc finger, C3HC4 type (RING finger)
    4.9e-07   29.5   2.9    7.6e-07   28.9   2.9    1.3  1  zf-C3HC4     Zinc finger, C3HC4 type (RING finger)
      7e-07   29.0   1.8      1e-06   28.5   1.8    1.3  1  zf-C3HC4_3   Zinc finger, C3HC4 type (RING finger)
    1.7e-06   28.2   2.5    4.1e-06   27.0   2.5    1.6  1  zf-rbx1      RING-H2 zinc finger domain
  ------ inclusion threshold ------
       0.02   14.7   3.3      0.036   13.9   3.3    1.4  1  Prok-RING_4  Prokaryotic RING finger family 4
       0.15   11.8   1.8       0.32   10.8   1.8    1.5  1  zf-RING_11   RING-like zinc finger
       0.16   12.1   0.3        0.4   10.8   0.2    1.6  2  zf-ANAPC11   Anaphase-promoting complex subunit 11 RING-H2 fi
       0.18   11.8   1.4       0.38   10.8   1.4    1.6  1  zf-RING_5    zinc-RING finger domain


Domain annotation for each model (and alignments):
>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.6   4.4   2.1e-12   4.1e-09       3      44 .]      31      71 ..      29      71 .. 0.90

  Alignments for each domain:
  == domain 1  score: 36.6 bits;  conditional E-value: 2.1e-12
   zf-RING_2  3 CpICleelssadsvlllpCgHv.fhreClerwlrssstCPlCr 44
                C+ICl+++s+a +++  pC+H  f++ Cl+ wl++++ CPlC+
  EEA18976.1 31 CVICLDAVSEAATAI--PCKHDnFDFLCLASWLQQRRVCPLCK 71
                ********9777766..8***66*******************7 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.0   4.6   3.5e-10     7e-07       2      40 .]      31      70 ..      30      70 .. 0.96

  Alignments for each domain:
  == domain 1  score: 29.0 bits;  conditional E-value: 3.5e-10
  zf-C3HC4_2  2 CpiCldmlkdpsvvtpCgH.vfCqkCilrsLeekneCPlC 40
                C iCld  +++ + +pC+H  f   C++ +L++   CPlC
  EEA18976.1 31 CVICLDAVSEAATAIPCKHdNFDFLCLASWLQQRRVCPLC 70
                *******************55999**************** PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.9   2.9   3.8e-10   7.6e-07       1      41 []      31      70 ..      31      70 .. 0.95

  Alignments for each domain:
  == domain 1  score: 28.9 bits;  conditional E-value: 3.8e-10
                -TTT-S--SS-E.E-TTS--.B-CHHHHHHHHCTSSB--TTT CS
    zf-C3HC4  1 CpiCleeakepnelleCkHs.fCskCirkilksrkkvkCPlC 41
                C iCl+ ++e+ ++++CkH  f + C+ ++l+  + + CPlC
  EEA18976.1 31 CVICLDAVSEAATAIPCKHDnFDFLCLASWLQ--QRRVCPLC 70
                9******************99***********..6667**** PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.5   1.8   5.1e-10     1e-06       3      48 ..      29      75 ..      27      77 .. 0.89

  Alignments for each domain:
  == domain 1  score: 28.5 bits;  conditional E-value: 5.1e-10
                SB-TTTSSSBS-.EEETTEEEEEE-HHHHHHHHHTT-B-TTT--B-- CS
  zf-C3HC4_3  3 eeCviClerprn.vvllpCgHlvlCeeCaekllkrkkkCpiCrrpie 48
                ++CviCl++ ++ ++ +pC+H  +   C+ ++l++++ Cp+C+++ +
  EEA18976.1 29 SPCVICLDAVSEaATAIPCKHDNFDFLCLASWLQQRRVCPLCKTDLT 75
                68******965537999**************************9875 PP

>> zf-rbx1  RING-H2 zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.0   2.5   2.1e-09   4.1e-06      12      55 .]      29      71 ..      24      71 .. 0.84

  Alignments for each domain:
  == domain 1  score: 27.0 bits;  conditional E-value: 2.1e-09
     zf-rbx1 12 eacieckapgdeecpvvlGeCgH.aFHlhCiskWlktrkvCPlcr 55
                ++c+ c    +e    ++  C+H +F + C+ +Wl++r+vCPlc+
  EEA18976.1 29 SPCVICLDAVSE-AATAI-PCKHdNFDFLCLASWLQQRRVCPLCK 71
                578888887777.66666.8***66*******************6 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   3.3   1.8e-05     0.036       1      40 [.      31      74 ..      31      78 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.8e-05
  Prok-RING_4  1 CvlCgeq.ekkailepCgHl.vCkeCfdsk..dlssCPlCqrri 40
                 Cv+C  +  + a  +pC+H  +   C+ s+  +   CPlC++ +
   EEA18976.1 31 CVICLDAvSEAATAIPCKHDnFDFLCLASWlqQRRVCPLCKTDL 74
                 ****98746667789****88888999999534449*****986 PP

>> zf-RING_11  RING-like zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   1.8   0.00016      0.32       2      22 ..      31      49 ..      31      57 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00016
  zf-RING_11  2 CsICLeefkpgqalfilpCsH 22
                C+ICL+ +  ++a +  pC+H
  EEA18976.1 31 CVICLDAV--SEAATAIPCKH 49
                ********..7788889**** PP

>> zf-ANAPC11  Anaphase-promoting complex subunit 11 RING-H2 finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.2    0.0002       0.4      51      81 ..      46      74 ..      12      78 .. 0.73
   2 ?   -3.1   0.0       4.3   8.6e+03      49      68 ..     256     275 ..     255     284 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.0002
                TTS-.EEEHHHHHHHHHHHSTSSB-TTTSSB- CS
  zf-ANAPC11 51 kckh.nfhlhcilkwletetskglcpmcrqtf 81
                 ckh nf   c+  wl+++     cp+c+  +
  EEA18976.1 46 PCKHdNFDFLCLASWLQQR---RVCPLCKTDL 74
                388758999*******986...5799998765 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 4.3
                 EBTTS-EEEHHHHHHHHHHH CS
  zf-ANAPC11  49 lGkckhnfhlhcilkwlete 68 
                 +G+ +  + lh +  wl ++
  EEA18976.1 256 IGRANARLFLHELNSWLRSP 275
                 57777788899999999765 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   1.4   0.00019      0.38       2      44 .]      31      72 ..      30      72 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00019
   zf-RING_5  2 CnkCfeklskeekfyltsCgH....ifCekClkkllekeavCpiCrk 44
                C +C + +  +e++   +C+H    +    Cl   l++++vCp+C++
  EEA18976.1 31 CVICLDAV--SEAATAIPCKHdnfdF---LCLASWLQQRRVCPLCKT 72
                99******..***********54444...5555555566******95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (361 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       649  (0.0361983); expected 358.6 (0.02)
Passed bias filter:                      408  (0.0227564); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.50u 0.24s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 2466.74
//
Query:       EEA18977.1  [L=297]
Description: regulatory protein SUAPRGA1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-71  240.7   1.3    1.9e-71  240.4   1.3    1.0  1  MAM33     Mitochondrial glycoprotein
  ------ inclusion threshold ------
      0.062   13.0   0.0       0.13   12.1   0.0    1.5  1  Thymosin  Thymosin beta-4 family


Domain annotation for each model (and alignments):
>> MAM33  Mitochondrial glycoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  240.4   1.3   2.1e-75   1.9e-71       1     212 []      73     295 ..      73     295 .. 0.96

  Alignments for each domain:
  == domain 1  score: 240.4 bits;  conditional E-value: 2.1e-75
       MAM33   1 LesEikyekeavkeeeeepesvkeflenggFeiedkpgkeevtLtrkfgdekIrvtfsvadlaneeeeeeeeeeeeedeaeeeeeeeeeeeee...... 93 
                 L++E+++e++ + e ee  + +k fl n+ +e++d +g++ev+Ltrkfg+ekIr tf+v+dl+n +e+e +  +e++ e+ ++ ++ e+ +++      
  EEA18977.1  73 LADELSHEQS-SGELEEPAAAIKAFLANSSWEVKDVAGEQEVVLTRKFGNEKIRATFTVSDLQNVAEDEFDGLSESDYENINQGQSGEHISTRpedsia 170
                 789*******.5889999**********************************************99999999888888888888888776666999*** PP

       MAM33  94 ........eeesfpvrlsvtiekpgksggaLelectaqdgefvidnvsyykdaelakeetaeadwkrrllyeGPpFenLDedLqellerYLeerGIdee 184
                         e ++fpvr+++tiekp   +gaL +++ta+dg+f+i++vs++++a+la++etae+dw+r++ly+GP+++nLDedLq+l+ rYLeerG ++e
  EEA18977.1 171 ssdrdfdgEIPGFPVRVNITIEKP--GNGALLIQTTASDGMFEIHEVSHFDKADLAEAETAEKDWHRQSLYSGPAYGNLDEDLQTLFDRYLEERGFNAE 267
                 ************************..56*********************************************************************** PP

       MAM33 185 laefipdysevkEqkeYvrWLenvkkFv 212
                 la+ ipdy++vkEqkeY+rWLe vkkFv
  EEA18977.1 268 LANIIPDYITVKEQKEYTRWLETVKKFV 295
                 ***************************8 PP

>> Thymosin  Thymosin beta-4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   1.4e-05      0.13       6      25 ..     213     232 ..     209     233 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 1.4e-05
    Thymosin   6 sevesFdkskLKkveTqEKn 25 
                  ev++Fdk+ L  +eT EK 
  EEA18977.1 213 HEVSHFDKADLAEAETAEKD 232
                 69*****************5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (297 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       459  (0.025601); expected 358.6 (0.02)
Passed bias filter:                      381  (0.0212505); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 1994.14
//
Query:       EEA18978.1  [L=181]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.4e-49  166.9   6.1      3e-49  166.6   6.1    1.1  1  Tma16      Translation machinery-associated protein 16
     0.0031   16.1   0.4     0.0041   15.7   0.4    1.1  1  MmgE_PrpD  MmgE/PrpD family
  ------ inclusion threshold ------
      0.041   14.5   1.9      0.041   14.5   1.9    2.1  2  HTH_32     Homeodomain-like domain
      0.082   13.0   0.0       0.68   10.1   0.0    2.1  2  FBA_2      F-box associated


Domain annotation for each model (and alignments):
>> Tma16  Translation machinery-associated protein 16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  166.6   6.1   6.7e-53     3e-49       2     144 ..      20     164 ..      19     166 .. 0.97

  Alignments for each domain:
  == domain 1  score: 166.6 bits;  conditional E-value: 6.7e-53
       Tma16   2 kkalHpkSRkakqLaraalRdeklakkkkerakkkssllervkffqealde..ekkplsleelkeliekylkRndeeleelkserrkgrpkskreelle 98 
                  +alH++SR+ak L+ra++R++++a+++++ + +++s l+rv +fqe l+e  e  ++++e++ eli+k+++R+d+el+el++errkgrp+skree l+
  EEA18978.1  20 LNALHEESRNAKILRRASAREDRIARVATSAMIARQSFLDRVVHFQECLEElsEPIAMTDEDIVELIHKWIHRSDDELQELQEERRKGRPPSKREENLK 118
                 689************************************************7666679***************************************** PP

       Tma16  99 ekkereeeeyetGfevpDLtdeenvkllreWngdlsslstlkfiri 144
                 +++ +ee+ey++Gf++pD+t++e  + l+ Wng++ssls lkfir+
  EEA18978.1 119 QRTVTEEKEYRSGFWMPDVTQQEVRQQLKIWNGEWSSLSALKFIRF 164
                 *********************************************8 PP

>> MmgE_PrpD  MmgE/PrpD family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.4   9.2e-07    0.0041     341     410 ..      72     144 ..      57     149 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 9.2e-07
                 CSCCCCTSCHHCCHHCCEEEEE-HHHHHHHTTT---...EEEEETTS-B---EEESS-TTSGGHHHHHHHHHH CS
   MmgE_PrpD 341 federladpevqaLrekvevvedpeltadypekrsi...vvvvlkdggrtleerveypkGhprnplsreelee 410
                  e+ +++d+++++L++k   + d+el++ ++e+r++    + + + ++rt++e+ ey  G +   ++++e+++
  EEA18978.1  72 SEPIAMTDEDIVELIHKWIHRSDDELQELQEERRKGrppSKREENLKQRTVTEEKEYRSGFWMPDVTQQEVRQ 144
                 455569************************999988999666666677889999***************9986 PP

>> HTH_32  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.1      0.63   2.8e+03      14      24 ..      20      30 ..       6      56 .. 0.52
   2 ?   14.5   1.9   9.1e-06     0.041       2      38 ..      86     122 ..      85     155 .. 0.66

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.63
      HTH_32 14 legLkdrprrg 24
                l +L++++r  
  EEA18978.1 20 LNALHEESRNA 30
                44555554442 PP

  == domain 2  score: 14.5 bits;  conditional E-value: 9.1e-06
      HTH_32   2 vsrwlkRyneeGlegLkdrprrgrpr.klsdevrarii 38 
                 +++w++R  ++ l+ L++++r+grp+ k  + +++r +
  EEA18978.1  86 IHKWIHR-SDDELQELQEERRKGRPPsKREENLKQRTV 122
                 89*****.5555*******9*****9655554444433 PP

>> FBA_2  F-box associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   0.00015      0.68      36      65 ..      71     101 ..      62     101 .. 0.86
   2 ?    0.2   0.0      0.19   8.6e+02      12      29 ..     145     162 ..     135     174 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00015
       FBA_2  36 ldnss.lsskdlNrFLKhWikgsnprLeyls 65 
                 l+++  ++++d+   + +Wi+ s ++L+ l+
  EEA18978.1  71 LSEPIaMTDEDIVELIHKWIHRSDDELQELQ 101
                 6677779********************9885 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.19
       FBA_2  12 eltikdsswltLddLLii 29 
                 +l+i++++w +L  L+ i
  EEA18978.1 145 QLKIWNGEWSSLSALKFI 162
                 677888888888888766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1240  (0.0691617); expected 358.6 (0.02)
Passed bias filter:                      590  (0.0329076); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 1283.48
//
Query:       EEA18979.1  [L=749]
Description: exonuclease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      6e-23   81.0   0.0    1.4e-22   79.8   0.0    1.7  1  XPG_I     XPG I-region
      7e-23   81.0   0.0    1.7e-22   79.8   0.0    1.6  1  XPG_N     XPG N-terminal domain
    0.00077   19.0   0.0     0.0014   18.1   0.0    1.4  1  XPG_I_2   XPG domain containing


Domain annotation for each model (and alignments):
>> XPG_I  XPG I-region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.8   0.0   2.4e-26   1.4e-22       2      94 .]     139     226 ..     138     226 .. 0.86

  Alignments for each domain:
  == domain 1  score: 79.8 bits;  conditional E-value: 2.4e-26
                 HHT--EEE-SS-HHHHHHHHHHTTSSSEEE-SSSHHHHTT-SEEEESTT.ECECTT..EEECEEEEEEHHHHHHHHT--HHHHHHHHHHHCET CS
       XPG_I   2 lmgipyvvApgEAEAqcayLqkkglvdaviseDsDlllFGapkvlrnlskkkskkkkekekkkvevidlekvlkelgltreqlidlaillgcD 94 
                  m+++yvvAp+EA+Aq++yL+++g+++++iseDsDll+FGa+++l +l   + +++   e +  +   + + ++ +g+++++++ ++il+gcD
  EEA18979.1 139 RMKVQYVVAPYEADAQLVYLERQGIINGIISEDSDLLVFGAKRLLSKLD--QHGDC--IEINRGDFAAC-RDISLIGWSDADFRRMCILSGCD 226
                 69**********************************************8..66667..22333444444.666789****************9 PP

>> XPG_N  XPG N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.8   0.0   2.8e-26   1.7e-22       1      99 [.       1      97 [.       1      99 [. 0.98

  Alignments for each domain:
  == domain 1  score: 79.8 bits;  conditional E-value: 2.8e-26
                X--TTHHHHHHHH-GEEEEEGGGGTTEEEEEEHHHHHHHHHHHSE.ETTEE-BS-HHHHHHHHHHHHHHHTTEEEEEEE--S--GGGHHHHHHHHHHHH CS
       XPG_N  1 MGikgLlkllkevaairsvsiealegkklaiDaslwlyrfliavreqlgnalentshlmglfsrllrlldfgikPifVFdgkapdlkkeelekrserrq 99
                MGikgL  llk ++  ++ +++++ g++l++Da+ wl+r  +a++++l+ ++ +t h+ ++++r+ +ll+fg++P++VFdg+ ++ k+++++ r ++r+
  EEA18979.1  1 MGIKGLHGLLKSIQ--KPCNLKKFDGQTLGVDAYGWLHRGTVACATELALSKPTTRHVDFVLNRVRMLLFFGVTPYLVFDGGDLPSKSGTEADRFKKRE 97
                **************..***************************************************************************99998886 PP

>> XPG_I_2  XPG domain containing
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   2.4e-07    0.0014       5      58 ..     129     178 ..     125     202 .. 0.85

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 2.4e-07
     XPG_I_2   5 mvpavieaLknrwkakditevvpgEADkfcAvlA.rklgcaVLTsDSDLlvhdlg 58 
                 m   +ie Lk    +k++++v p EAD++  +l  +     + ++DSDLlv+  g
  EEA18979.1 129 MARQLIEELK---RMKVQYVVAPYEADAQLVYLErQGIINGIISEDSDLLVF--G 178
                 667889****...7***************9999966677889*********9..4 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (749 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       676  (0.0377043); expected 358.6 (0.02)
Passed bias filter:                      455  (0.0253779); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.28s 00:00:00.90 Elapsed: 00:00:00.44
# Mc/sec: 5144.55
//
Query:       EEA18980.1  [L=267]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.5e-57  192.0   5.2    9.5e-57  192.0   5.2    2.0  2  Fig1             Ca2+ regulator and membrane fusion protein F
    1.3e-06   28.2   6.9    1.8e-06   27.8   6.9    1.2  1  SUR7             SUR7/PalI family
     0.0014   17.7   3.4     0.0014   17.7   3.4    1.8  2  DUF898           Bacterial protein of unknown function (DUF89
  ------ inclusion threshold ------
      0.041   13.3   0.1      0.057   12.9   0.1    1.1  1  SAM_adeno_trans  S-adenosyl-l-methionine hydroxide adenosyltr
       0.98   10.2   0.0       0.98   10.2   0.0    3.6  4  DUF751           Protein of unknown function (DUF751)


Domain annotation for each model (and alignments):
>> Fig1  Ca2+ regulator and membrane fusion protein Fig1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   1.2     0.018        65      78     109 ..      17      47 ..      10      55 .. 0.75
   2 !  192.0   5.2   2.7e-60   9.5e-57       3     188 .]      74     256 ..      72     256 .. 0.97

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.018
        Fig1  78 hpyllmvaiiLtlllfllllyfplgseipllP 109
                 + ++lm+ i+L+++l+ lll   + s  p +P
  EEA18980.1  17 YHHVLMMLIALAIILLSLLLA-GCSSSSPQIP 47 
                 56899999***9999998865.3355666665 PP

  == domain 2  score: 192.0 bits;  conditional E-value: 2.7e-60
        Fig1   3 tksanstggleelevrvGYlGvCvdkspksliCrkksnatelasllslsssssskstsdplnlvelakkfsdnvvhpyllmvaiiLtlllfllllyfpl 101
                 t+ an+ gg++ +evrvG++G+C++ +++++iC  + nat+la++++         ++dpln ++la+ f+d+vv+pyl++va++L++++f+ll++fp+
  EEA18980.1  74 TAIANIIGGAT-MEVRVGFFGICISPDNGAFIC--NANATALAEVVT--------VDQDPLNVIWLAERFKDTVVFPYLIIVALVLAFFCFILLATFPG 161
                 56678878888.*********************..************........899***************************************** PP

        Fig1 102 ........gseipllPfkskavskvalvlsflllllwlvgalwqhvassaastlveeasmgivkskvGkkaealgWfafaflllvclglwvlilr 188
                         gse+++ Pf+s++vs+val l+ ++++++lv++lwqh+as+aast+v+ +++g++ks vG++a++lgWf+f++l++v++gl+v+il+
  EEA18980.1 162 wheeidasGSEREVRPFPSRPVSQVALTLIGISSVFVLVSVLWQHTASVAASTMVQGLANGSLKSGVGSSAMVLGWFGFGLLVVVTIGLLVMILS 256
                 ********************************************************************************************986 PP

>> SUR7  SUR7/PalI family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   6.9     5e-10   1.8e-06       5     211 ..      21     248 ..      18     254 .. 0.76

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 5e-10
        SUR7   5 llflslaalilllfailgsiknstplt.....siylskfdlsgldlaqi.............gladvysfgvwgyCdnsdvnytkCskpkagypfdple 85 
                 l+ l++ a+ill + ++g+ ++s  +      siy  k+  + +d aq+             g     ++g++g+C + d++  +C     +       
  EEA18980.1  21 LMMLIALAIILLSLLLAGCSSSSPQIPtifliSIYYEKYTPT-FDPAQVdpgvstaianiigGATMEVRVGFFGICISPDNGAFICNANATALAEV--V 116
                 556666677777777777775555554445556676666666.777777*************999999********************87777444..6 PP

        SUR7  86 elnsesngkvdlPsnlrktlsklnnltkalfilhiialvlsfislvvgllaic...............vspdnsrllsflnlllsvlsflatllaalld 169
                  ++++  + + l +++++t+            l+i+alvl f ++++  la +               v p  sr +s ++l+l  +s +++l+++l++
  EEA18980.1 117 TVDQDPLNVIWLAERFKDTVVF--------PYLIIVALVLAFFCFIL--LATFpgwheeidasgsereVRPFPSRPVSQVALTLIGISSVFVLVSVLWQ 205
                 67777776777*********96........88889999888877765..44444445777777666664444444599999999999999999999999 PP

        SUR7 170 tllfvfvrkkin.lkefgikaslglkflafaWlalaaallvvi 211
                   + v +   ++ l +   k+ +g + + + W  + ++++v+i
  EEA18980.1 206 HTASVAASTMVQgLANGSLKSGVGSSAMVLGWFGFGLLVVVTI 248
                 9999988888889999999999999999988988888877766 PP

>> DUF898  Bacterial protein of unknown function (DUF898)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.1     0.094   3.4e+02     190     204 ..      21      35 ..       8      89 .. 0.66
   2 !   17.7   3.4     4e-07    0.0014     181     308 ..     137     262 ..     125     266 .. 0.61

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.094
      DUF898 190 lfllglvlliallaa 204
                 l++l+++++i+l ++
  EEA18980.1  21 LMMLIALAIILLSLL 35 
                 222222222222222 PP

  == domain 2  score: 17.7 bits;  conditional E-value: 4e-07
      DUF898 181 ykiwlaavllfllglvlliallaalltevlakeaaatadaskseaellk.......lavllilalvllllallaaayykarifnlvwnnttlegarfks 272
                 + ++l++v+l+l++++ ++++++    e ++++  + + +        +       +a+ li +  +++l+ ++++   +     +++  +l + ++ks
  EEA18980.1 137 VFPYLIIVALVLAFFCFILLATFPGWHEEIDASGSEREVRP-------FpsrpvsqVALTLIGISSVFVLVSVLWQHTASVAASTMVQ--GLANGSLKS 226
                 33444444444444444444444433333333333333332.......1334444466666666666555555555555555555555..4566689** PP

      DUF898 273 slrardlvllyitnlllllltLGlarpwarvrlary 308
                  + + ++vl +++  ll+++t+Gl++ ++++++ r 
  EEA18980.1 227 GVGSSAMVLGWFGFGLLVVVTIGLLVMILSISILRR 262
                 *******************************99885 PP

>> SAM_adeno_trans  S-adenosyl-l-methionine hydroxide adenosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.1   1.6e-05     0.057      63     117 ..      65     134 ..      48     149 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.6e-05
                      EEE--TTTTSS--EEE....EEETTSEE...EEESSSTTHHHH...SEEEEEEGSSCC.....--TS-HH CS
  SAM_adeno_trans  63 lavVDpgvgterralv....veakggyf...vgPDNGlltlal...lleeaveieeee.....ssatFhg 117
                       a VDpgv t+   ++    +e++ g+f   + PDNG + + +    l+e+v+++++       ++ F+ 
       EEA18980.1  65 PAQVDPGVSTAIANIIggatMEVRVGFFgicISPDNGAFICNAnatALAEVVTVDQDPlnviwLAERFKD 134
                      578********9999866665556555555599*******999765448999998766666663355555 PP

>> DUF751  Protein of unknown function (DUF751)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.6       3.2   1.1e+04      38      47 ..      25      34 ..      19      38 .. 0.47
   2 ?    2.1   1.2     0.091   3.3e+02      26      56 ..     127     156 ..     124     158 .. 0.61
   3 ?   10.2   0.0   0.00027      0.98      27      55 ..     175     203 ..     173     205 .. 0.91
   4 ?   -1.3   0.6       1.1   3.8e+03      51      54 ..     244     247 ..     215     260 .. 0.62

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 3.2
      DUF751 38 ialigllvgg 47
                ial ++l+++
  EEA18980.1 25 IALAIILLSL 34
                3333333333 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.091
      DUF751  26 plkpllknpvtaialigllvgglaflyftLr 56 
                 +l++++k  v    li+ ++ +laf+ f+L 
  EEA18980.1 127 WLAERFKDTVVFPYLII-VALVLAFFCFILL 156
                 77777777665544443.3445677777775 PP

  == domain 3  score: 10.2 bits;  conditional E-value: 0.00027
      DUF751  27 lkpllknpvtaialigllvgglaflyftL 55 
                 ++p+ ++pv+++al+++ ++++++l+ +L
  EEA18980.1 175 VRPFPSRPVSQVALTLIGISSVFVLVSVL 203
                 678999*******************9887 PP

  == domain 4  score: -1.3 bits;  conditional E-value: 1.1
      DUF751  51 lyft 54 
                 ++ t
  EEA18980.1 244 VVVT 247
                 2222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (267 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1195  (0.0666518); expected 358.6 (0.02)
Passed bias filter:                      559  (0.0311785); expected 358.6 (0.02)
Passed Vit filter:                        67  (0.00373696); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.58u 0.31s 00:00:00.88 Elapsed: 00:00:00.49
# Mc/sec: 1654.56
//
Query:       EEA18981.1  [L=506]
Description: DNA primase subunit Pri1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.5e-59  199.8   0.3    5.6e-59  199.2   0.3    1.2  1  DNA_primase_S  DNA primase small subunit


Domain annotation for each model (and alignments):
>> DNA_primase_S  DNA primase small subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  199.2   0.3   3.1e-63   5.6e-59       1     176 [.     185     413 ..     185     413 .. 0.99

  Alignments for each domain:
  == domain 1  score: 199.2 bits;  conditional E-value: 3.1e-63
                    EEEEEETTT-.....TT--HHHHHHHHHHHHHHHHHHHH-----GGGEEEEE--SEEEEEEE--TTEEES-HHHHHHHHHH............... CS
  DNA_primase_S   1 FDiDmddydd....cseatvcekcwkfvsvavkvldellredfgfkdilwvfsgrrGfHcwvsdkdarpltdeeraaivnylnly........... 81 
                    FDiDm+dydd    cs+a++c kcw f++ a+kv+d++lredfgf++ilwv+sgrrG+H+wv d++ar+l d +r+ai+ yl+l+           
     EEA18981.1 185 FDIDMTDYDDvrtcCSKANICHKCWSFITMAIKVVDTALREDFGFEHILWVYSGRRGAHAWVGDHRARNLPDDRRKAIAGYLELVkgndksgkrvn 280
                    9*********************************************************************************************** PP

                    ....................................HCHHHHCT--------............................................ CS
  DNA_primase_S  82 ..rplhpflsrsmlkivkpvveeiileeqdpf....eikkllrllpdkslre..kkkw...............................eakediv 138
                      rplhp+++rs  k ++p+++++ l++qd f    + ++ll llpdk+l +  + kw                                a++div
     EEA18981.1 281 vkRPLHPHVARS-VKLLEPHFNQTTLIDQDVFlgeqQAERLLGLLPDKKLNDalRRKWdstpdrsstnkwndivtlaktingidaralkDARYDIV 375
                    ************.*****************************************9999999999999999*******************99***** PP

                    .......-----------------....---------. CS
  DNA_primase_S 139 lvllyprldeqvtkgikhllkapfcihgktgnvcvpld 176
                    l+++yprld +v+k+ +hllk+pf ih++tg+vcvp+d
     EEA18981.1 376 LEYTYPRLDAEVSKKMIHLLKSPFVIHPGTGRVCVPMD 413
                    ************************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (506 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       589  (0.0328518); expected 358.6 (0.02)
Passed bias filter:                      467  (0.0260472); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.47
# Mc/sec: 3204.19
//
Query:       EEA18982.1  [L=286]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    6.7e-07   29.3  44.3    6.7e-07   29.3  44.3    3.0  3  Mucin-like  Mucin-like


Domain annotation for each model (and alignments):
>> Mucin-like  Mucin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.3  44.3   3.7e-11   6.7e-07       8      97 ..      43     132 ..      32     135 .. 0.86
   2 ?    1.4  34.0     0.018   3.3e+02       9      82 ..     100     173 ..      99     177 .. 0.88
   3 ?   -0.8   0.7     0.089   1.6e+03      28      43 ..     240     254 ..     221     258 .. 0.42

  Alignments for each domain:
  == domain 1  score: 29.3 bits;  conditional E-value: 3.7e-11
  Mucin-like   8 qppaspsssygepsraPsssytapsrapsssygepprdpsssytapqsapsssytappstp.sssygeppaapsssytapprdpsssytap 97 
                  +pa+p+s yg+p+ +P+s y+ p+ +p s yg+pp+dp+s y++p+ ++ s y++pp +   s yg pp++ ++s++  p + s+syt+p
  EEA18982.1  43 PAPADPKSTYGPPPADPKSTYGPPPADPKSTYGPPPADPKSTYGPPPPEHKSTYGPPPPADlKSTYG-PPPPEHKSTYPVPPPASHSYTEP 132
                 456*****************************************************99976588888.6666666666688889******9 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.018
  Mucin-like   9 ppaspsssygepsraPsssytapsrapsssygepprdpsssytap.qsapsssytapps...tpsssygeppaapsss 82 
                 ppa+ +s yg+p+++ +s y  p+ + s+sy+ep    +ssy +p q  p +sy++pp+   tp +sy++p  +p++s
  EEA18982.1 100 PPADLKSTYGPPPPEHKSTYPVPP-PASHSYTEP---GHSSYPKPtQTPPPHSYSEPPKpysTPHNSYSKPVVPPPNS 173
                 89999*******************.89*****96...67888888566899*******99999******998777766 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 0.089
  Mucin-like  28 ytapsrapsssygepp 43 
                  tap+  p ss ++ p
  EEA18982.1 240 PTAPP-VPASSASANP 254
                 23333.3333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (286 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       451  (0.0251548); expected 358.6 (0.02)
Passed bias filter:                      180  (0.0100396); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.30s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 1876.42
//
Query:       EEA18983.1  [L=548]
Description: threonine synthase Thr4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      2e-29  101.6   0.0    5.8e-29  100.1   0.0    1.9  1  Thr_synth_N  Threonine synthase N terminus
    1.3e-17   64.2   0.0    4.4e-17   62.4   0.0    1.8  1  PALP         Pyridoxal-phosphate dependent enzyme


Domain annotation for each model (and alignments):
>> Thr_synth_N  Threonine synthase N terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.1   0.0   6.4e-33   5.8e-29       1      79 []       8      87 ..       8      87 .. 0.99

  Alignments for each domain:
  == domain 1  score: 100.1 bits;  conditional E-value: 6.4e-33
  Thr_synth_N  1 kYiSTRgeaeklsfeeallkGlAeDgGLyvPeeiPklsaeeleelrklsYaelafevlklfi.edeipeedLkeliekaY 79
                 +Y+STRg++  lsfee++lkGlA+DgGL++Pe+iP+l a + +e+r+ls+++laf++++l+i ++eip++dLk++i+++Y
   EEA18983.1  8 RYLSTRGSSYGLSFEEVVLKGLASDGGLFIPEQIPELPAGWETEWRDLSFEDLAFKIFSLYIsTSEIPSDDLKDIIRRSY 87
                 7******************************************************************************9 PP

>> PALP  Pyridoxal-phosphate dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.4   0.0   4.9e-21   4.4e-17       3     274 ..      91     463 ..      89     476 .. 0.78

  Alignments for each domain:
  == domain 1  score: 62.4 bits;  conditional E-value: 4.9e-21
                 GCSSS--EEEECCTCCCCCCEEEEEEGGGSTTSBTTHHHHH...HHHHH.HHTT........TTTSEEEEEBSSHHHHHHHHHHHHH.T-EEEEEEETT CS
        PALP   3 lgigpTPlvrlprlskelgvplflKlEslnptgSfKdRgae...yllar.lkeg........tgaktvveassGNhgralAaaaall.Glkvtivvpad 88 
                  ++ +TPlv+l + +     +l l   ++ pt +fKd +++   +++++ l ++        +   tv+ a+sG++g a+++  +    + v i++p++
  EEA18983.1  91 RHEQRTPLVELSKDK-----KLHLLELFHGPTFAFKDVALQflgNMFEYfLVRKnngkegkdRHHLTVIGATSGDTGSAAIYGLRGKkDVSVFILFPKG 184
                 6889*******9954.....5788777778***********6665555583333456777888999*******************7769********** PP

                 S-H..HHHHHHHHTT-EEEEE..CCHHHHHHHHHHHHHHH..STTCEE--TTTSHHHHHH.HHTHHHHHH......HHTTTTEEEEEEE-SSSHHHHHH CS
        PALP  89 asp..ekvallrllGaevvev..ggdydeavaaaaelaae..gegaylvsqfdnptvieg.ygtiglEil......eqlggkpdavvvpvGgGgliaGi 174
                 + +  ++++++  l a+v+    +g++d+++++++ l a+   ++ ++v    n+ +++   ++i + ++      +q+g +   +vvp G+ g i + 
  EEA18983.1 185 KVSpiQQAQMTTVLDANVHNLtvEGTFDDCQDIVKSLFADadLNSTHNVAAI-NSINWCRiLAQISYYFYsyfqltKQVGSASVRFVVPSGNFGDILAG 282
                 9954599999**********999************99999666666666666.78888888999999998776667777755556************** PP

                 HHHHHHHSTT-EEEEEEECTTCGGTTCCS..S.SS..B............................................................. CS
        PALP 175 aaglkerrpdvrvigvepegsdalarslragrrvtvpvs............................................................ 213
                 +++ + + p  +++++ +e +d l r+++ g + t ++                                                             
  EEA18983.1 283 WFAKRMGLPAEKLVIATNE-NDILDRFFKSGGHYTKKPIhgkaaegglvqdgvkaheegvketyspamdilvssnferllwfltfdaetgsiderrqna 380
                 **********999999665.9999999987777777777799999999999998888888888888888888888888888888888888888888777 PP

                 ....SSS.CCSTCS...CGTTCCHHHHSEEEEEEEEEEHHHHHHHHHHHH................HHHSB-B-HHHHHHHHHH CS
        PALP 214 ....dtiadglavg...spselafelldrlvdeivtvsdeealeamrlla................rregivvepssaaalaal 274
                      ++ + l+ +   s+se ++e +++       vsdee+le +r  +                ++ g++++p+sa+++ a 
  EEA18983.1 381 skriASWLSELKSQggfSVSEAVLEGAKKEFE-SERVSDEETLEVIRNIYtssfpanlgpgsahssKTGGYILDPHSAVGVGAS 463
                 75554444444444455555555555544444.777888888888887777777777777777777777777777777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (548 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       356  (0.0198561); expected 358.6 (0.02)
Passed bias filter:                      346  (0.0192983); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.30s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 3517.15
//
Query:       EEA18984.1  [L=539]
Description: mitochondrial chaperone bcs1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.8e-33  113.7   2.2    1.1e-32  113.6   0.8    1.7  2  BCS1_N    BCS1 N terminal
      7e-16   58.8   0.0    1.8e-07   31.7   0.0    2.7  2  AAA       ATPase family associated with various cellular acti
     0.0082   16.4   0.1      0.025   14.8   0.1    1.8  1  AAA_28    AAA domain
  ------ inclusion threshold ------
      0.036   13.6   0.0      0.068   12.7   0.0    1.4  1  AAA_25    AAA domain
      0.059   13.8   0.2       0.14   12.5   0.2    1.8  1  AAA_16    AAA ATPase domain
       0.07   13.1   0.0       0.25   11.3   0.0    2.1  2  AAA_5     AAA domain (dynein-related subfamily)
        0.1   12.0   0.0       0.19   11.0   0.0    1.4  1  ATPase    KaiC


Domain annotation for each model (and alignments):
>> BCS1_N  BCS1 N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.6   0.8   4.2e-36   1.1e-32       4     187 .]      46     245 ..      39     245 .. 0.82
   2 ?   -1.7   0.0      0.96   2.5e+03      86     132 ..     489     531 ..     456     535 .. 0.54

  Alignments for each domain:
  == domain 1  score: 113.6 bits;  conditional E-value: 4.2e-36
      BCS1_N   4 llaaarrllselaslirrrflvsveissdDeaydwvlaWlsaqpasrrs.relsvetrtksrssdssaee...dededeee...dg............. 82 
                 +++++r+l+++++      ++v+v+i++dD++y+ +++W++ +++++r  r++++ +++ks ++d+++     +          +g             
  EEA18984.1  46 IFTFLRYLFTRIII-----LWVTVRINEDDQLYQSLMRWMADHQFMNRQfRSVKAVSASKSSWEDEEDALksmT------TaggSGdkkiltepdpnnl 133
                 44455555555544.....59****************************************9966655544331......1233113456666777889 PP

      BCS1_N  83 ......kkkkplrylPavgtthlfrykgrllavtRereekssdsetgapeetltltclgrsreilkeLleearelalkkqegktviyraa..agsggeW 173
                         ++p++++P  g th+fr +g+++++++  ++ s+   + ++   ++ +c+g s +++++Lleea+ ++l++++ +t+++ra    ++  +W
  EEA18984.1 134 isyrtiVGRSPISLQPFQG-THIFRRHGSWILFQHVIRKGSELVPQDRESGYIQMKCVGSSFAPVQSLLEEAQLYHLERTKTTTTVHRAIsnVREMIRW 231
                 9999995577*********.7*************999777776666666777************************************66997889*** PP

      BCS1_N 174 rrvasRpkRplstV 187
                 +++++Rp+R++stV
  EEA18984.1 232 TTFSARPSRDMSTV 245
                 *************9 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.96
      BCS1_N  86 kplrylPavgtthlfrykgrllavtRereekssdsetgapeetltlt 132
                 +  + +P  +   l   +g ll+++R+ ee     +t a++ ++tl+
  EEA18984.1 489 RFAESVPERK-FSLAALQGFLLQYKRSPEE---ACSTAAEWAEITLQ 531
                 3444555555.3555667777788888754...33456678888875 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4   0.0   1.2e-08   3.1e-05       2      74 ..     283     347 ..     282     373 .. 0.81
   2 !   31.7   0.0   6.9e-11   1.8e-07      76     131 ..     385     440 ..     372     441 .. 0.87

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 1.2e-08
                 EEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHH CS
         AAA   2 llyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksr 74 
                 l++G pGtGKT+l +a+a  +g +++ +s+ +        +e+ +  l++e+   +  +i+++++ida + +r
  EEA18984.1 283 LFSGAPGTGKTSLTSALAGVFGLDIYVLSLLDPN-----MNESALMRLMSEV--PS-RCIVLLEDIDAAGLNR 347
                 89*******************9998888888877.....4566666666665..33.5**********99998 PP

  == domain 2  score: 31.7 bits;  conditional E-value: 6.9e-11
                 TCCCHHHHHHHHHHHHHHHHTTTSSSTEEEEEEESSGGGSTHHHHS.TTSSEEEETT CS
         AAA  76 gseseeeervvnqLlteldgvkkkeskvivigatnrpdkldpallr.gRfdrkieie 131
                 +++s  ++  ++ Ll+++dgv+++e+  i+i++tn+p++ld+al+r gR+d++i +e
  EEA18984.1 385 SNASAATSVSLSGLLNAIDGVSSQEG-RILIMTTNSPESLDKALIRpGRVDMHIAFE 440
                 456777888899***********766.9**************************997 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.1   9.6e-06     0.025       3      20 ..     283     300 ..     282     310 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 9.6e-06
      AAA_28   3 vitGgestGKTtlleaLa 20 
                  ++G+++tGKT+l++aLa
  EEA18984.1 283 LFSGAPGTGKTSLTSALA 300
                 589**************9 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   2.7e-05     0.068      18      54 ..     264     300 ..     249     303 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.7e-05
      AAA_25  18 pppprrwlvkgllpagelallaGapgtGKttlaldla 54 
                  p+ rrw+    +p     l+ GapgtGKt l++ la
  EEA18984.1 264 HPHTRRWYANHGIPYRRGYLFSGAPGTGKTSLTSALA 300
                 5889999999888*********************998 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.2   5.5e-05      0.14      24      45 ..     277     300 ..     256     415 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 5.5e-05
      AAA_16  24 p..elvllsGesGvGKsslvrell 45 
                 p  +  l+sG++G+GK+sl  +l+
  EEA18984.1 277 PyrRGYLFSGAPGTGKTSLTSALA 300
                 4558899************99987 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   9.9e-05      0.25       3      43 ..     283     324 ..     281     344 .. 0.87
   2 ?   -3.0   0.0       2.6   6.7e+03     114     135 ..     411     428 ..     389     429 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 9.9e-05
                 EEE--SSSSHHHHHHHGGGGB.S--EEEEE--TT--HHHHH- CS
       AAA_5   3 lLvGppGtgKselaerlaaal.nreveyvqltrdtteedlkg 43 
                 l  G+pGtgK++l+  la ++  + ++  +l  +++e+ l  
  EEA18984.1 283 LFSGAPGTGKTSLTSALAGVFgLDIYVLSLLDPNMNESALMR 324
                 678******************777788888999999998875 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 2.6
                 -EEEEEESS--.-TT-TTHHHH CS
       AAA_5 114 frviatanpldrslnelspalr 135
                   +i+t+n+++    +l++al+
  EEA18984.1 411 RILIMTTNSPE----SLDKALI 428
                 67899999988....6777775 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   7.5e-05      0.19      13      35 ..     273     295 ..     247     300 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 7.5e-05
      ATPase  13 kgGipegrvvlitGepGtGKtif 35 
                 + Gip +r +l +G pGtGKt +
  EEA18984.1 273 NHGIPYRRGYLFSGAPGTGKTSL 295
                 48*******************76 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (539 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       852  (0.0475208); expected 358.6 (0.02)
Passed bias filter:                      730  (0.0407162); expected 358.6 (0.02)
Passed Vit filter:                        95  (0.00529868); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.66u 0.31s 00:00:00.97 Elapsed: 00:00:00.45
# Mc/sec: 3568.02
//
Query:       EEA18985.1  [L=436]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.28   12.2   0.1       0.28   12.2   0.1    2.7  2  TraV      Type IV conjugative transfer system lipoprotein (Tr
        0.3   10.3  11.7      0.052   12.8   8.0    1.6  2  LegC3_N   LegC3 N-terminal coiled-coil domain
        3.2    6.9   4.6        5.2    6.2   4.6    1.4  1  Zip       ZIP Zinc transporter


Domain annotation for each model (and alignments):
>> TraV  Type IV conjugative transfer system lipoprotein (TraV)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   4.0      0.43   2.6e+03      39      93 ..      16      69 ..       3      95 .. 0.56
   2 ?   12.2   0.1   4.6e-05      0.28      22     109 ..     103     222 ..      87     224 .. 0.64

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.43
        TraV 39 kekklaettskakvssktlakasvssqarvaaekaarasvyaevasllesPstap 93
                k  ++++  + +  ss +l++++ ++  ++++ +++++ ++ e a+++ +Ps+ p
  EEA18985.1 16 KAFNQSAGIKRRGSSSSQLPSKKGKKDVKPNEGNGYQKPTVTEEAQEI-KPSEDP 69
                222232244456667778888888888888888888888774444433.233322 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 4.6e-05
        TraV  22 ekakakeepsdakpaaakekklaettskakvssktlakasvssqarvaaekaarasvy..............................aevasllesPs 90 
                 ++ k+kee++++k ++++++kla+  +  k ++k++++a+  +q++ + +++++  v+                              +++  l  +P+
  EEA18985.1 103 KEEKEKEEKEKEKEEKKELEKLADGIPAGKEEEKEEKPATKEAQTAIKISPERE-DVLpssilekgivyfffrprvnvedphsisdvaRSFFVLQPTPK 200
                 334444455555555555555555555555555555555555555555544443.33346667999999999999999999999977766666666666 PP

        TraV  91 tapr...PlrkpaevmrlwiaP 109
                  a+    P+r   +  rl+i+P
  EEA18985.1 201 GAKIedgPIRDDTANCRLLILP 222
                 6544888999999999999999 PP

>> LegC3_N  LegC3 N-terminal coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   8.0   8.7e-06     0.052      72     116 ..      94     138 ..      53     158 .. 0.89
   2 ?   -3.1   0.1       0.6   3.6e+03      98     195 ..     392     407 ..     380     419 .. 0.57

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 8.7e-06
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHH CS
     LegC3_N  72 kqQlkEDkkekerdeeeerkdkkqkekLtreleaikaekseyere 116
                 +  +kEDk++ e+++ee++k+k++k++L +  + i+a k+e ++e
  EEA18985.1  94 EGGVKEDKEKEEKEKEEKEKEKEEKKELEKLADGIPAGKEEEKEE 138
                 5569********************************999887665 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 0.6
                 HHHHHHTTHHHHHHHHHHHHHHHHHHHHTT---------------------------SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
     LegC3_N  98 kLtreleaikaekseyerellllelklerllesqtkvevtqhsqpvvkkllsssshsatierlelslqdleekirsllerevnikkeLkeleerakeR 195
                 +                                                                                    +eL++lee ++eR
  EEA18985.1 392 DPA----------------------------------------------------------------------------------QELDQLEEENEER 407
                 333..................................................................................3444444444444 PP

>> Zip  ZIP Zinc transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   4.6   0.00088       5.2     118     172 ..      67     134 ..      16     183 .. 0.73

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.00088
         Zip 118 ssesaakksvsndkveeseekedhvaeadtdadskeelrngkqeksesekeqas.............e 172
                 + + +++ +v+++++e   ek  + a++++ ++ ke++ ++k+ek+++++e+++             e
  EEA18985.1  67 EDPTKVQTTVNMQPTEAPPEKSVEPAQEGGVKEDKEKEEKEKEEKEKEKEEKKElekladgipagkeE 134
                 33556666677777777777777777777777777777777777777777766666666777776642 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (436 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1857  (0.103575); expected 358.6 (0.02)
Passed bias filter:                      691  (0.0385409); expected 358.6 (0.02)
Passed Vit filter:                       124  (0.00691617); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.78u 0.30s 00:00:01.08 Elapsed: 00:00:00.48
# Mc/sec: 2719.00
//
Query:       EEA18986.1  [L=243]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (243 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       590  (0.0329076); expected 358.6 (0.02)
Passed bias filter:                      291  (0.0162307); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.42
# Mc/sec: 1739.97
//
Query:       EEA18987.1  [L=1208]
Description: Coatomer subunit alpha, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.8e-143  478.8   0.2   1.2e-142  476.1   0.0    2.0  2  Coatomer_WDAD  Coatomer WD associated region
   1.7e-106  356.4   0.1   2.5e-106  355.8   0.1    1.1  1  COPI_C         Coatomer (COPI) alpha subunit C-terminus
    1.8e-37  126.7  16.8    3.7e-07   30.7   0.3    7.4  7  WD40           WD domain, G-beta repeat
      1e-08   35.4   0.8       0.18   12.1   0.0    5.5  5  ANAPC4_WD40    Anaphase-promoting complex subunit 4 WD40 doma
     0.0034   16.1   5.7       0.62    8.6   0.1    3.5  4  Nup160         Nucleoporin Nup120/160
  ------ inclusion threshold ------
      0.041   13.7   1.8       0.19   11.6   0.0    2.8  3  Clathrin       Region in Clathrin and VPS


Domain annotation for each model (and alignments):
>> Coatomer_WDAD  Coatomer WD associated region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.0     0.095   2.8e+02     104     151 ..      94     144 ..      32     149 .. 0.77
   2 !  476.1   0.0  4.1e-146  1.2e-142       1     444 [.     347     776 ..     347     777 .. 0.99

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.095
                    XXXXXXXXXXXXX....XXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXX CS
  Coatomer_WDAD 104 sikleyqvdkifg....GalLgvksegsvsfYDweqgklvrridvkkvknVv 151
                    si +  +v+ +        +L  ++++++ +++w++++l++ ++ ++ ++V+
     EEA18987.1  94 SIAVLSDVRTVAFhhelPWILSCSDDQTIRIWNWQNRSLIATLTGHN-HYVW 144
                    666666666665556666688889999999**********9999888.7765 PP

  == domain 2  score: 476.1 bits;  conditional E-value: 4.1e-146
                    XXXXXXXXXXXX....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXX.......XXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Coatomer_WDAD   1 esevrqanikkkeelkdgellslqlkelgsieiypqslshnpngrfvlV...cgdgeyiiyt.......alalrnkaygkgldfvwvssnrfavle 86 
                    e++v+++++ k+     ++++ l+l++lg  ++  +++s+np++r++lV    ++g+y++++       a++ +n+ +g+g+++v+v++nrfav++
     EEA18987.1 347 EKQVKSYDFTKN----AESQPLLSLRKLGAPWVPLRTISYNPAERAILVttpAENGTYELIHlprdgtgAVEPTNSLRGQGNSAVFVARNRFAVFN 438
                    589*********....899***************************************************************************** PP

                    X.XXXXXX.XXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX... CS
  Coatomer_WDAD  87 s.sksvkifknfkekktksikleyqvdkifg...GalLgvksegsvsfYDweqgklvrridvkkvknVvwsddgelvalvskdtvyilsynleave 178
                    + +++v i k++++++tksik+++ +++i+    GalL++++++ vs++D++q+k+++++ v+ vk+Vvws+dg ++al+sk++v+i+++nl+   
     EEA18987.1 439 QaNQTVDI-KDLSNSTTKSIKTPTGTTDIYFggsGALLFITPTS-VSLFDIQQKKQLAELAVSGVKYVVWSNDGLHAALLSKHNVTIVTKNLQ--- 529
                    ********.********************999************.************************************************... PP

                    ..........XXXXXXX.XXXXXXXXXXXX.XXXXXXXX.XXXX.XXXXXXXXXXXXXXXXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Coatomer_WDAD 179 eedeeegvedafevlhelsesiksgaWvgd.vfiYttsnnrlky.lvngevgiikhldktlyilgykgkenklylldkdgnvvsleidlselefkt 272
                              +++++he +++iks++W+++ +++Y++ n ++k+ l+ng++gii++ld+t+y++++kg  +++y+ld++++ +++eid++e++fk+
     EEA18987.1 530 ----------QLSSIHE-TIRIKSATWDDSgILYYSSLN-HIKFsLLNGDNGIIRTLDQTVYLVKVKG--RNVYCLDRNAKPQIFEIDPTEFRFKS 611
                    ..........*******.************999999999.****************************..************************** PP

                    XXXXXXXXXXXXXXXXXXXX.......XXXXXXXXXXXXXXXX-GGGSS-HHHHHHHHHHTT-HHHHHHHHHHH--HHHHHHHHHHHHHTT-HHHH CS
  Coatomer_WDAD 273 avlrkdleevlkiiaasnllpeipkeegqkiirfLekkgypelAlqlvqDpetkFdLAlelgnLelAlelakelddeekWkkLgdaAlsqgnikla 368
                    a+++++++e+l++i++s+l+       gq+ii++L+kkgype+Alq+vqDp+t+F+LA+e+gnL++A+e+ake d+++ W++L+++Al++gn++ +
     EEA18987.1 612 ALVKRNYDEMLHLIKTSSLV-------GQSIIAYLQKKGYPEIALQFVQDPQTRFELAIECGNLDVAIETAKEIDRPKLWSRLATEALAHGNHQTV 700
                    ********************.......********************************************************************* PP

                    HHHHHHTT-HHHHHHHHHHHT-HHHHHHHHHHHHHTT-HHHHHHHHHHHT-HHHHHHHHHHTT-HHHHHHHHHHTT CS
  Coatomer_WDAD 369 eeayqkakdfdkLllLylstgnkekLkkLakiaekkgdyniafqaalllgdvekcvdlLiksgrlpeAalfAktyg 444
                    e+ yqk++ fdkL++Lylstg++ekL+++akia +++d++++fq+a++ gdve++++++++++ +p+A+++Ak++g
     EEA18987.1 701 EMGYQKQRLFDKLSFLYLSTGDQEKLSRMAKIATHRNDFTSRFQNAIYRGDVEDRIEMFKEVDLYPLAYVTAKAHG 776
                    **************************************************************************98 PP

>> COPI_C  Coatomer (COPI) alpha subunit C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  355.8   0.1  8.5e-110  2.5e-106      30     397 ..     838    1203 ..     813    1207 .. 0.90

  Alignments for each domain:
  == domain 1  score: 355.8 bits;  conditional E-value: 8.5e-110
                  XXXXXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXX---HHHHHHHH---HHHHHHHT-HHHHHHH CS
      COPI_C   30 gWgddedldlee..kkeeeededeeeeedeeeggWdv.edlelpadldaeaaasaaaesevfvaPtkgvpvsqiWvnksqlaadhvaaGsFetAmrL 123 
                  g  +++ ld+ee  ++ +++ +d  eee+e+ +gWd+ ++++++ +++   +        + v   ++++++  W+++s laadhvaaGsF+tAm+L
  EEA18987.1  838 GAEEEAALDIEEeeEEAAAAGQDVLEEEEEDVAGWDMgDEIAVE-EVNDFVS-------VENVDAGASISEADLWARNSPLAADHVAAGSFDTAMQL 926 
                  344566778877323444455566668888899***96666665.3333333.......3345667899**************************** PP

                  HHHHS-----GGGHHHHHHHHHHS-EEE-SSTTS--EEE--BTTTTT--SSS--B-----HHHHHH.HHHHHHHHHHHT-HHHHHHHHHHHHHHGGG CS
      COPI_C  124 LnrqvGvvnfaplkslFlelyaasrtslealpslpsllvalernwkeaaaknglPalvlklsqlee.rLkaaYklttegkfseavekfrsillsipl 219 
                  LnrqvG v+faplks F+e+y+asrt+l+a + lp+l+ +++r+++e+ +++ lP +  +l+++++  L+++Y ++ + k++e v+ f++il+++++
  EEA18987.1  927 LNRQVGAVQFAPLKSRFMEIYTASRTYLPASTGLPPLVNYVRRTVDETDSRKVLPIIPRDLETIASvDLQEGYAAMRSNKLEEGVKIFKRILHTLLV 1023
                  ****************************************************************9999***************************** PP

                  ----SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS-SS..HHHHHHHHHHHHHHHS---HHHHHHHHHHHHHHHHHHTBHHHHHHHHHHHHHH---H CS
      COPI_C  220 lvvdskqevdevkeLieicreYivgLrmEikRkelkks..ddqkrqaElaAYfthcnlqpvHliLaLrsAlnlffKlknfktaasfarrLLelgpke 314 
                   vv+s +ev+++k++i  +reYi+++++E++R+ ++ +  +d kr+ El+AYft  +l+ +H++LaL+ A++l+f  kn+++a sfa+r++  g ++
  EEA18987.1 1024 NVVSSESEVEQAKKIIATAREYILAMSIELERRATPTEnpEDLKRALELSAYFTIPKLEVAHRQLALMAAMKLAFQNKNYSSALSFANRMIANGGSA 1120
                  ************************************9898899****************************************************** PP

                  HHHHHHHHHHHHHHHS--BSS--S--SSS---BBTTT--B--TTS--EE-TTT--EE-GGGTTSB-TTTSSSBSS-------- CS
      COPI_C  315 evaqqarkvlqaceknptdevelnYdernPFvvcaatfvPiYrgkkevkcplcgasyvpelkgkvckvcevaeiGkdaiGLri 397 
                  ++ +qa+k+ + ce+np+d++e+++d+   F++caa+++PiY g+++v++p++ga+y++++kg+v +++ev+eiG+ a+GLr+
  EEA18987.1 1121 KLLEQAKKIKAQCERNPHDKIEVDFDQFADFEICAASYTPIYSGSPSVSDPYTGAKYHEQYKGTVDRIAEVTEIGAPASGLRL 1203
                  *********************************************************************************97 PP

>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.8   0.1    0.0047        14      15      38 .]      23      46 ..      17      46 .. 0.91
   2 !   26.7   0.0   2.4e-09     7e-06       5      38 .]      54      88 ..      50      88 .. 0.89
   3 !   25.2   0.2   6.8e-09     2e-05      12      38 .]     100     126 ..      92     126 .. 0.92
   4 !   30.7   0.3   1.2e-10   3.7e-07       2      38 .]     131     168 ..     130     168 .. 0.94
   5 !   21.1   0.0   1.3e-07    0.0004       6      37 ..     208     240 ..     204     241 .. 0.90
   6 !   22.0   0.3     7e-08   0.00021       4      38 .]     250     285 ..     247     285 .. 0.89
   7 ?   -2.1   0.0         3   8.9e+03      23      37 ..     312     325 ..     304     326 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0047
                EEEEETTSSEEEEE.ETTSEEEEEE CS
        WD40 15 slafspdgawlasG.sdDgtvriWd 38
                +laf+p  +wl+ + +   t+ +Wd
  EEA18987.1 23 GLAFHPTRPWLLVSlH-SSTIQLWD 46
                799********99956.*******9 PP

  == domain 2  score: 26.7 bits;  conditional E-value: 2.4e-09
                EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38
                  ++ H ++v+s+af+p ++ ++sG+dD ++r+W+
  EEA18987.1 54 DRFEEHdGPVRSVAFHPTQNIFVSGGDDYKIRLWS 88
                56889*888*************************5 PP

  == domain 3  score: 25.2 bits;  conditional E-value: 6.8e-09
                 SEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  12 svtslafspdgawlasGsdDgtvriWd 38 
                 +v+ +af+++ +w++s+sdD+t+riW+
  EEA18987.1 100 DVRTVAFHHELPWILSCSDDQTIRIWN 126
                 7999**********************8 PP

  == domain 4  score: 30.7 bits;  conditional E-value: 1.2e-10
                 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 
                 +++ tltGH++ v++ +f+p  ++++s+s D++vr+Wd
  EEA18987.1 131 SLIATLTGHNHyVWCAQFHPKEDLIVSASLDQSVRVWD 168
                 57889****888*************************9 PP

  == domain 5  score: 21.1 bits;  conditional E-value: 1.3e-07
                 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 
                 +l+GH  +v+ +af+p  ++++s++dD+ v++W
  EEA18987.1 208 ILEGHdRGVNFCAFHPTLPLIVSAGDDRLVKLW 240
                 689**666************************* PP

  == domain 6  score: 22.0 bits;  conditional E-value: 7e-08
                 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 + t++GH ++ +++ f+p++++++s ++D+t+r+Wd
  EEA18987.1 250 VDTCRGHfQNASACIFHPHQDLILSVGEDKTIRVWD 285
                 67899**86688888*********9999*******9 PP

  == domain 7  score: -2.1 bits;  conditional E-value: 3
                 SEEEEEETTSEEEEE CS
        WD40  23 awlasGsdDgtvriW 37 
                 +++a+G+ D  v+++
  EEA18987.1 312 NLFAAGH-DTGVMVF 325
                 5589999.9998886 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.3   0.0    0.0082        25      36      79 ..      16      59 ..      10      61 .. 0.90
   2 !   10.2   0.0   0.00025      0.73      35      77 ..      57      99 ..      55     149 .. 0.89
   3 ?    2.0   0.1     0.087   2.6e+02      35      68 ..     137     170 ..     114     184 .. 0.67
   4 !   12.1   0.0   6.1e-05      0.18       2      78 ..     220     297 ..     219     336 .. 0.91
   5 ?   -1.4   0.0         1     3e+03       9      52 ..     511     551 ..     480     591 .. 0.68

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0082
  ANAPC4_WD40 36 kedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvk 79
                 +++s+ ++La++p    L v+ + ++++l d   g+++  ++ +
   EEA18987.1 16 SKSSRAKGLAFHPTRPWLLVSLHSSTIQLWDYRMGTLIDRFEEH 59
                 5778999*****************************99988765 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.00025
  ANAPC4_WD40 35 dkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhsls 77
                 +++d+ vrs+a++p  ++++ + +d ++rl + +s k +  ls
   EEA18987.1 57 EEHDGPVRSVAFHPTQNIFVSGGDDYKIRLWSLQSRKSIAVLS 99
                 57899*****************************999887665 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.087
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdgevrlldae 68 
                  +++++ v + +++p++ l++ a  d +vr+ d++
   EEA18987.1 137 TGHNHYVWCAQFHPKEDLIVSASLDQSVRVWDIS 170
                  5666677777777777777777777777777765 PP

  == domain 4  score: 12.1 bits;  conditional E-value: 6.1e-05
  ANAPC4_WD40   2 swcptmDLiAlatedgellvfRlngqrvwtl.eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsv 78 
                  ++ pt  Li  a +d  + + R++  + w++ +  ++ ++ ++  ++p   l+  + +d ++r+ d ++ + v+s++ 
   EEA18987.1 220 AFHPTLPLIVSAGDDRLVKLWRMSDTKAWEVdTCRGHFQNASACIFHPHQDLILSVGEDKTIRVWDLNKRTSVQSFKR 297
                  5789999************************44456678899999**************************9999975 PP

  == domain 5  score: -1.4 bits;  conditional E-value: 1
  ANAPC4_WD40   9 LiAlatedgellvfRlngqrvwtleedkedsevrsLaWkpdgkl 52 
                  L A   ++ ++ +   n q++ ++   +e  +++s  W  +g l
   EEA18987.1 511 LHAALLSKHNVTIVTKNLQQLSSI---HETIRIKSATWDDSGIL 551
                  444445555555555666666666...56666666666666655 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0      0.52   1.5e+03     239     256 ..      81      99 ..      67     109 .. 0.83
   2 ?    1.9   0.6     0.023        69     232     255 ..     112     135 ..      88     142 .. 0.83
   3 !    6.2   0.1    0.0011       3.4     228     253 ..     148     175 ..     138     247 .. 0.70
   4 !    8.6   0.1   0.00021      0.62     218     255 ..     257     294 ..     234     304 .. 0.73

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.52
                 T-EEEEEETTTTEEEEE.E CS
      Nup160 239 dgkLrvWnlltgkclat.i 256
                 d+k+r+W+l++ k +a+  
  EEA18987.1  81 DYKIRLWSLQSRKSIAVlS 99 
                 99********999888755 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.023
                 EEEEEETT-EEEEEETTTTEEEEE CS
      Nup160 232 ylfalsrdgkLrvWnlltgkclat 255
                  +++ s d+++r+Wn ++ +++at
  EEA18987.1 112 WILSCSDDQTIRIWNWQNRSLIAT 135
                 5788999*************9998 PP

  == domain 3  score: 6.2 bits;  conditional E-value: 0.0011
                 ...TTTEEEEEETT-EEEEEETTTTEEE CS
      Nup160 228 i..gqtylfalsrdgkLrvWnlltgkcl 253
                    ++++++++s+d+ +rvW+++ ++  
  EEA18987.1 148 FhpKEDLIVSASLDQSVRVWDISGLRKK 175
                 344899***************9876544 PP

  == domain 4  score: 8.6 bits;  conditional E-value: 0.00021
                 EEEEET.....TTTEEEEEETT-EEEEEETTTTEEEEE CS
      Nup160 218 sldvavavveigqtylfalsrdgkLrvWnlltgkclat 255
                  ++++  + + +q++++++  d+++rvW+l+  + + +
  EEA18987.1 257 FQNASACIFHPHQDLILSVGEDKTIRVWDLNKRTSVQS 294
                 45555555566*******************98877766 PP

>> Clathrin  Region in Clathrin and VPS
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   6.2e-05      0.19      67     140 ..     626     696 ..     611     699 .. 0.77
   2 ?   -1.0   0.0      0.51   1.5e+03      72     102 ..     751     781 ..     701     797 .. 0.53
   3 ?   -1.2   0.1      0.55   1.6e+03      26     104 ..    1018    1108 ..    1008    1126 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 6.2e-05
                 S---S-TTHHHHHHHT-SSHHHHHHHHHT.TXTHSSHSSXSSSSHCSCHHHHTTTTTXXSHHHHHHHHHHHSSXS CS
    Clathrin  67 knnnydlekvaklcekadlyeeavilykk.inefkkaisllkklkdfddaieyaakvsnpelwekllealldkkp 140
                 k+++   ++++ +++k+++ e a+   ++   +f+ ai+     +++d aie+a++++ p+lw++l+ + l +++
  EEA18987.1 626 KTSSLVGQSIIAYLQKKGYPEIALQFVQDpQTRFELAIE----CGNLDVAIETAKEIDRPKLWSRLATEALAHGN 696
                 445556788999999999999999888883445555555....499********************998887765 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.51
                 -TTHHHHHHHT-SSHHHHHHHHHTTXTHSSH CS
    Clathrin  72 dlekvaklcekadlyeeavilykkinefkka 102
                 d+e  +++ ++ dly +a++  k+++ +++a
  EEA18987.1 751 DVEDRIEMFKEVDLYPLAYVTAKAHGLTEEA 781
                 3333344444555555555555555555555 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 0.55
                  HCHHHCCHHHCHTS...--HHHHHHHHHHHHHT..........T-HHHHHHTTSS---S-TTHHHHHHHT-SSHHHHHHHHHTTXTHSSHSS CS
    Clathrin   26 lleyLekvlkedsk...enpalqtallelyaky..........ddpqeleeflkknnnydlekvaklcekadlyeeavilykkinefkkais 104 
                  l  +L +v++  s+   + +++ ta  +++a +          ++p++l + l+ + ++ ++k+    ++  l+  +++ ++ +++++ a+s
  EEA18987.1 1018 LHTLLVNVVSSESEveqAKKIIATAREYILAMSielerratptENPEDLKRALELSAYFTIPKLEVAHRQLALMAAMKLAFQ-NKNYSSALS 1108
                  6666666664333334455555555555555556677777777556999999999999999998777777777766666666.777776666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1208 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       601  (0.0335211); expected 358.6 (0.02)
Passed bias filter:                      483  (0.0269396); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.86u 0.35s 00:00:01.21 Elapsed: 00:00:00.50
# Mc/sec: 7278.35
//
Query:       EEA18988.1  [L=197]
Description: FAD dependent sulfhydryl oxidase Erv1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.5e-29  100.4   3.1    6.5e-29  100.4   3.1    1.5  2  Evr1_Alr  Erv1 / Alr family
  ------ inclusion threshold ------
       0.29   10.6   1.2       0.33   10.4   1.2    1.2  1  CAP_N     Adenylate cyclase associated (CAP) N terminal


Domain annotation for each model (and alignments):
>> Evr1_Alr  Erv1 / Alr family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.1       1.2   1.1e+04      41      50 ..      31      40 ..      30      51 .. 0.67
   2 !  100.4   3.1   7.2e-33   6.5e-29       1     100 []      92     188 ..      92     188 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 1.2
                SCHHHHHHHH CS
    Evr1_Alr 41 pCeeCaehfe 50
                pC+ C +  +
  EEA18988.1 31 PCKTCTSAAS 40
                7888876654 PP

  == domain 2  score: 100.4 bits;  conditional E-value: 7.2e-33
                 HHHHHHHHHHHHCSHSS..HHHHHHH-CHHHHHHHHHHHSSCHHHHHHHHHHHH....HCH.CCCGSSHHHHHHHHHHHHHHHHHHTT...T-HHCHHH CS
    Evr1_Alr   1 cslWtllHtlaaevpekpteeqqkelavlkaflkliakfypCeeCaehfekvla....enppekevesrdelvlWlweaHNeVnkrlakeefdcsedkv 95 
                 +s+Wt+lHtl+a++p++ ++e+q+++   ++fl l++++ypC+ Cae+f+++++    +n+p+  ++sr e+ +W++eaHN Vn++l+k+efdc+   +
  EEA18988.1  92 RSTWTFLHTLTATYPTTASTEKQTQM---RSFLGLFSNLYPCWACAEDFRNWMSdptgKNEPR--LSSRAEFGQWMCEAHNAVNRKLGKKEFDCR--LW 183
                 79*************99999999999...************************9555444444..8*****************************..99 PP

                 CCCCC CS
    Evr1_Alr  96 kerwp 100
                 +erw+
  EEA18988.1 184 EERWR 188
                 ****6 PP

>> CAP_N  Adenylate cyclase associated (CAP) N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   1.2   3.7e-05      0.33     231     258 ..      35      80 ..      17     127 .. 0.56

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 3.7e-05
                 ........................SSC--XXXXXXX....XXXXXXXX CS
       CAP_N 231 alk....................aaaaaasaaaaggpppPpPpPppas 258
                  ++                    a  aaa++aaa+++  P+PpPp a+
  EEA18988.1  35 CTSaaswramlkqastsggiaagA--AAAATAAASATSTPAPPPPSAQ 80 
                 444444555555555566665432..2222222233222333332222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (197 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       896  (0.0499749); expected 358.6 (0.02)
Passed bias filter:                      575  (0.0320709); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 1405.32
//
Query:       EEA18989.1  [L=338]
Description: transcriptional regulator, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      0.002   18.0   0.1     0.0073   16.2   0.1    2.0  1  DEK_C     DEK C terminal domain


Domain annotation for each model (and alignments):
>> DEK_C  DEK C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.1   4.1e-07    0.0073       3      38 ..      29      64 ..      27      72 .. 0.94

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 4.1e-07
       DEK_C  3 deeirkaireiLreaDLdtvTkkkvReqLeeklgvd 38
                ++ +r+++ +i r+  L+++T k vR + e+ lg d
  EEA18989.1 29 EKALRDTVANIFRTGKLEELTVKRVRLATENALGLD 64
                789******************************988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (338 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1590  (0.0886831); expected 358.6 (0.02)
Passed bias filter:                      576  (0.0321267); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.42
# Mc/sec: 2409.93
//
Query:       EEA18990.1  [L=484]
Description: integral membrane protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.1e-13   49.8   0.1    1.1e-10   40.9   0.0    2.8  2  Glyco_transf_54  N-Acetylglucosaminyltransferase-IV (GnT-IV) 
  ------ inclusion threshold ------
      0.076   12.9   0.0       0.45   10.4   0.0    2.0  2  Glyco_transf_25  Glycosyltransferase family 25 (LPS biosynthe
       0.18   10.6   0.0       0.28   10.0   0.0    1.2  1  CReP_N           eIF2-alpha phosphatase phosphorylation const


Domain annotation for each model (and alignments):
>> Glyco_transf_54  N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.9   0.0   1.9e-14   1.1e-10      42     198 ..     103     264 ..      67     272 .. 0.75
   2 !    4.8   0.0    0.0018        11     255     283 ..     430     458 ..     417     463 .. 0.74

  Alignments for each domain:
  == domain 1  score: 40.9 bits;  conditional E-value: 1.9e-14
  Glyco_transf_54  42 rtgvslvlGiptvkrekksylldTlesllselseeekkdlvvvvfiaetdeeyvksvveeikkkfkkevesgllevisppasyYpnlsklkktl 135
                       t  +l +G+pt +r++++y+  T+ sl+++l+++e+ +++  ++ia t+++ + +   + ++   +++   +l    ++       + +++t+
       EEA18990.1 103 PTLPRLCIGMPTARRSQEQYVDITIASLFAQLTPQERAQILFNLLIAHTNPDEHPFYDGSASTVNASRLADNVLFYHDIAGG----SKAMTNTI 192
                      555679*********************************************9888877777666666665555543333332....45677778 PP

  Glyco_transf_54 136 nDskervkwrtkqnldyafLml.yaqskgeyylqleDdvvakkgfltkikkfvlakks........keWlvl 198
                         +e+ k++ k   dy +L++  a+s + y l leDdv+a++g+++   + +++ +          eWl+l
       EEA18990.1 193 RQLEEKGKFHEKSYYDYDLLLHqCAASMAPYILILEDDVLAQEGWYARTMESLQKLDTepgisrlgGEWLYL 264
                      888999***********988752688999**************97765544444443336666666666665 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.0018
  Glyco_transf_54 255 rekeklrirfkpSlFqhvgtqSslegkiq 283
                      +e++  r  + pS Fqh+g+q   e+k  
       EEA18990.1 430 NEQNLQRYALVPSAFQHIGAQTYKESKNS 458
                      45555667778**********98777765 PP

>> Glyco_transf_25  Glycosyltransferase family 25 (LPS biosynthesis protein)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   7.5e-05      0.45      77     114 ..     212     249 ..     209     273 .. 0.76
   2 ?   -0.7   0.0      0.18   1.1e+03     163     191 ..     369     397 ..     356     404 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 7.5e-05
  Glyco_transf_25  77 lWekcvelnleyiiIlEDDvilseefkealedllkeik 114
                      l ++c    ++yi+IlEDDv+ +e   +  ++ l++ +
       EEA18990.1 212 LLHQCAASMAPYILILEDDVLAQEGWYARTMESLQKLD 249
                      5578888889***********99987777766666655 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.18
  Glyco_transf_25 163 yllssevagtaGYlltpkaAkkllkalke 191
                        +++++++ ++++  +++A kll+ + e
       EEA18990.1 369 HVMNNYGCCSQAFVFRRTMALKLLDWFDE 397
                      5678999*****************98866 PP

>> CReP_N  eIF2-alpha phosphatase phosphorylation constitutive repressor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   4.7e-05      0.28     140     193 ..     391     446 ..     383     468 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 4.7e-05
      CReP_N 140 pldWLeegihWqcsssdLele..lkakgraLdpaahaflLeqqlWgveLlpsslqa 193
                  ldW++e+i   + s+d + e   k  ++++d+a ++f  eq l +  L+ps++q 
  EEA18990.1 391 LLDWFDERIAADIKSTDPNNEngRKYLRGSVDSAMEVFANEQNLQRYALVPSAFQH 446
                 69**********99999766611566689*************************94 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (484 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       720  (0.0401584); expected 358.6 (0.02)
Passed bias filter:                      566  (0.031569); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.46
# Mc/sec: 3177.25
//
Query:       EEA18991.1  [L=762]
Description: AP-1 adaptor complex subunit beta, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   3.9e-138  461.3   6.6     5e-138  460.9   6.6    1.0  1  Adaptin_N      Adaptin N terminal region
    5.3e-64  215.1   3.6    2.3e-60  203.3   0.7    2.7  3  Cnd1           non-SMC mitotic condensation complex subunit 1
      2e-18   66.5   5.0      1e-08   35.4   0.0    6.2  7  HEAT_2         HEAT repeats
    7.5e-14   50.7   2.9     0.0047   17.1   0.0    6.6  6  HEAT           HEAT repeat
    8.5e-05   22.5   1.3       0.43   10.7   0.0    5.3  5  Arm            Armadillo/beta-catenin-like repeat
     0.0019   17.8   0.0        9.4    5.7   0.0    3.7  3  CLASP_N        CLASP N terminal
      0.002   18.6   6.2       0.77   10.3   0.0    5.8  6  HEAT_EZ        HEAT-like repeat
     0.0054   16.9   0.3        1.1    9.4   0.0    3.8  4  RTP1_C1        Required for nuclear transport of RNA pol II C
  ------ inclusion threshold ------
      0.043   13.2   0.0      0.075   12.4   0.0    1.3  1  DUF2817        Protein of unknown function (DUF2817)
       0.31   10.9   2.4        1.4    8.8   0.7    3.0  2  Sec7_N         Guanine nucleotide exchange factor in Golgi tr


Domain annotation for each model (and alignments):
>> Adaptin_N  Adaptin N terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  460.9   6.6  2.8e-141    5e-138       4     522 ..      16     532 ..      14     534 .. 0.95

  Alignments for each domain:
  == domain 1  score: 460.9 bits;  conditional E-value: 2.8e-141
                 HCCHHHHHHCCSSS-SCHHHHHHHHHHHHHHHCT---GHHHHHHHCCCCSS-CHHHHHHHHHHHHHCTTSCCHHCCCCHHHHHHCCSSSHHHHHHHHHH CS
   Adaptin_N   4 riqqelaeilnsnkdddekkkeavkkliylialGedvsflffevvklvaskdfelKrlvYlylellaeesedlalLvtnslqkDlkdpnqlirglALrv 102
                  ++ el++ l s+  +  ++k+a+++ i  ++lG+dvs lf++v+k++a+ d+ +K+lvYlyl+++a++++dl++L++n++ +D kdpn+lir+lA+r+
  EEA18991.1  16 GETFELRAGLVSQ--YAYERKDAIQRTIMAMTLGKDVSALFPDVLKNIATTDLDQKKLVYLYLMNYAKSNPDLCILAVNTFVQDSKDPNPLIRALAIRT 112
                 5677888899999..999********************************************************************************* PP

                 HCCC--CCCHHHHHHHHHHHHT-SSHHHHHHHHHHHHHCCCCCHHCCCCC.HHHHHHHCTT-SSHHHHHHHHHHHHHH..HCCCCCCCHHHHHHHCCHH CS
   Adaptin_N 103 LssirvpelaedlapaikkllkdrspyvrkkAalailklykkdpdllrkq.lveeikellsdkdpgvvlaAvalleei..kkndrlllkllpklvrrLc 198
                 +++irv+++++++ + ++k+lkd+spyvrk+Aa++++kl++++   + ++ ++e ++el+ d +p+vv++Av++l ei    ++  +l++ +   r+L 
  EEA18991.1 113 MGCIRVDKMVDYMGEPLRKTLKDESPYVRKTAAICVAKLFDLNRTMCLENgFLETLQELIGDPNPMVVANAVTALAEIseSAPETKALDINSATLRKLL 211
                 ******************************************************************************855555555599999999999 PP

                 HHHHCS-HHHHHHHHHHHCC---SSHHHH..HHHHHHHCGGCGCSSCHHHHHHHHHCC......HCCCCSTHHHCCHHCHHHHHHSSCCTCHHHHHCHH CS
   Adaptin_N 199 nllteldpwlqvkiiklltrlarqepeerskkellesllnllqssnnaVlletvnliv......elapknelivlavnaLvrllsskdenlryvaLrtl 291
                  +l+e+++w+ v+i+++l +   ++ +++  + ++e++ +++q++n++V+l++v++++      + + +++ +++++  Lv+l+ss +e ++yvaLr++
  EEA18991.1 212 MALNECTEWGRVTILNCLAEFRTTDVKDA--EHICERVVPQFQHVNASVVLAAVKVVFlhmryiSSELATSYLKKMAPPLVTLVSSAPE-VQYVALRNI 307
                 999**************************..56************************9977755444455599****************.********* PP

                 HHHHHHXXTTTTTTTCCCCSXXTTSXHHHHHHHHHHHCCCXXTTTHHHHHHHHHHHTTSSXXHHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHTTXX CS
   Adaptin_N 292 lkivkkepkavqhldlkifllktdddvsirlkaldlllklvdesNvkeivkeLkkyvkevadedfksklvkaIgrlaekfatdaewvldvllellslsg 390
                   +++k+ + + +++l++f++k++d+ +++  +l++++++++e+Nv++++ eLk+y+ ev d df++++v+aIg+ a+k++++ e+++++ll+l+ ++ 
  EEA18991.1 308 DLLLQKQ-PDILNKELRVFFCKYNDPPYVKFQKLEIMVRIANEKNVDQLLAELKEYALEV-DMDFVRRAVRAIGQTAIKIESSSERCVNTLLDLINTKV 404
                 *******.99***********************************************999.************************************** PP

                 HHHHHHHHHHHHHHHHHSTTTSTTCHHHHCCTCCGXXSHHHHHHHHHHHHHTTTTXTT...HHHHHHCTTTTTTTSXHHHHHHHHHHHHHHHHCXGCC. CS
   Adaptin_N 391 esvkdeivevirdliqkvpelheeiiekLaellekieseearaaaiWllGeygelvsntesasdllrslaekfvlesekvklqiltalvKlyltspdke 489
                 ++v++e+++vird+++k+p   e+ii +L++ ++++++++araa+iW++Gey+e++sn   a d+l  + e f +e ++++lqilta vKl+l  p+k 
  EEA18991.1 405 NYVVQEAIVVIRDIFRKYPGY-ENIIPTLCKCIDELDEPNARAALIWIVGEYAEKISN---AGDILAGFVEGFNEEFTQTQLQILTAVVKLFLKRPEKA 499
                 ********************9.99**********************************...***********************************654 PP

                 THXHHHHHHHHHHH..XXSHHHHHHHHHHHHHHCC CS
   Adaptin_N 490 tqekliqlvlslat..ssdlevrdRaveylqllss 522
                 +   l+q vl+ at  +++ ++rdRa+ y++lls+
  EEA18991.1 500 Q--GLVQKVLQAATkeNDNPDIRDRAYVYWRLLSN 532
                 4..677777777777989**************987 PP

>> Cnd1  non-SMC mitotic condensation complex subunit 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       3.8   6.8e+03      93     130 ..      50      83 ..      41      86 .. 0.74
   2 !  203.3   0.7   1.3e-63   2.3e-60       1     160 [.     104     266 ..     104     268 .. 0.98
   3 !   11.8   0.0    0.0001      0.19       6     152 ..     374     517 ..     371     526 .. 0.76

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 3.8
        Cnd1  93 iynllpdiisklsdalnecsewgqitilefLlsyipkd 130
                 +  l+pd+++++     + + ++ + ++ +L++y +++
  EEA18991.1  50 VSALFPDVLKNIA----TTDLDQKKLVYLYLMNYAKSN 83 
                 6667778887777....567788888888899988765 PP

  == domain 2  score: 203.3 bits;  conditional E-value: 1.3e-63
        Cnd1   1 liRalairtlgcirvpnlveylvepLrkrLkDedpyVRktaaivvakL..ilndmvkekgflselaklleDenprVvanalaalteisek.senaiynl 96 
                 liRalairt+gcirv+++v+y+ epLrk+LkDe+pyVRktaai+vakL  ++++m+ e+gfl++l++l+ D+np+Vvana++al eise   e++++ +
  EEA18991.1 104 LIRALAIRTMGCIRVDKMVDYMGEPLRKTLKDESPYVRKTAAICVAKLfdLNRTMCLENGFLETLQELIGDPNPMVVANAVTALAEISESaPETKALDI 202
                 7*****************************************************************************************76689**** PP

        Cnd1  97 lpdiisklsdalnecsewgqitilefLlsyipkdkqeaeslveklcprlqhansavvlaaikvi 160
                 ++ ++ kl++alnec+ewg++til++L+++ + d ++ae+++e+++p++qh+n +vvlaa+kv+
  EEA18991.1 203 NSATLRKLLMALNECTEWGRVTILNCLAEFRTTDVKDAEHICERVVPQFQHVNASVVLAAVKVV 266
                 **************************************************************98 PP

  == domain 3  score: 11.8 bits;  conditional E-value: 0.0001
        Cnd1   6 airtlg..cirvpnlveylvepLrkrLkDedpyVRktaaivvakLilndmvkekgflselaklleDen.prVvanalaalteiseksenaiynllpdii 101
                 a+r++g  +i++++  e  v+ L   ++ +  yV + a++v+  ++++     ++++ +l k++++ + p+ +a  + +  e++ek      ++  di+
  EEA18991.1 374 AVRAIGqtAIKIESSSERCVNTLLDLINTKVNYVVQEAIVVIRDIFRKYP-GYENIIPTLCKCIDELDePNARAALIWIVGEYAEKI-----SNAGDIL 466
                 78999999999999999999999999999999999999988888776554.556789999999976651444444455555555553.....3456777 PP

        Cnd1 102 sklsdalnecsewgqitilefLlsyipkdkqeaeslveklcprlqhansav 152
                   +++  ne   ++q +il+++++   k  ++a+ lv+k+ +  +++n+  
  EEA18991.1 467 AGFVEGFNEEFTQTQLQILTAVVKLFLKRPEKAQGLVQKVLQAATKENDNP 517
                 77777777778899**********88888888**********999998765 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.4   0.0    0.0068        12      33      63 ..      91     121 ..      83     126 .. 0.75
   2 !   35.4   0.0   5.8e-12     1e-08       2      77 ..     127     220 ..     126     227 .. 0.74
   3 ?    0.1   0.0      0.61   1.1e+03       4      54 ..     210     265 ..     207     287 .. 0.60
   4 !    6.1   0.0    0.0081        14       3      87 ..     288     378 ..     285     379 .. 0.75
   5 !   17.1   0.0   2.9e-06    0.0052      12      84 ..     366     449 ..     352     453 .. 0.81
   6 !    7.5   0.0     0.003       5.4       1      83 [.     429     523 ..     429     525 .. 0.77
   7 ?   -1.7   0.3       2.2   3.9e+03      36      55 ..     599     620 ..     587     639 .. 0.52

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0068
      HEAT_2  33 lpaLvellededpavRraaaeaLgaigdpea 63 
                 ++++v+  +d++p +R+ a++++g i+ ++ 
  EEA18991.1  91 VNTFVQDSKDPNPLIRALAIRTMGCIRVDKM 121
                 5556666688999999999999987766555 PP

  == domain 2  score: 35.4 bits;  conditional E-value: 5.8e-12
      HEAT_2   2 daLlqalendpdpevrraairaLg...rignpea.......lpaLvellededpavRraaaeaLgaig...........dpealpaLkelldddddd 77 
                 ++L + l +d++p+vr++a+++ +   +++   +       l++L el+ d++p+v ++a++aL++i            ++++l+ L+++l++ +++
  EEA18991.1 127 EPLRKTL-KDESPYVRKTAAICVAklfDLNR--TmclengfLETLQELIGDPNPMVVANAVTALAEISesapetkaldiNSATLRKLLMALNECTEW 220
                 5789999.9***************7653333..22344445*************************9633333333323355778888887777766 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.61
      HEAT_2   4 LlqalendpdpevrraairaLgrignpea......lpaLvellededpavRraaaea 54 
                 Ll al n   +  r +++ +L++++++++       + +v+  ++ ++ v  aa++ 
  EEA18991.1 210 LLMAL-NECTEWGRVTILNCLAEFRTTDVkdaehiCERVVPQFQHVNASVVLAAVKV 265
                 55556.444445688999999988887554433335555555566677777777765 PP

  == domain 4  score: 6.1 bits;  conditional E-value: 0.0081
      HEAT_2   3 aLlqalendpdpevrraairaLg..rignpealpaLvell..eded.pavRraaaeaLgaigd....pealpaLkellddddddvvReaAaeaL 87 
                 +L+ ++  ++ pev++ a+r++    ++ p++l+  +++   +  d p+v  +  e +++i++    ++ l+ Lke++++ d d+vR+a ++a+
  EEA18991.1 288 PLVTLV--SSAPEVQYVALRNIDllLQKQPDILNKELRVFfcKYNDpPYVKFQKLEIMVRIANeknvDQLLAELKEYALEVDMDFVRRA-VRAI 378
                 566655..57799**********76567788877666655456566589************8623336678999999999888999985.7776 PP

  == domain 5  score: 17.1 bits;  conditional E-value: 2.9e-06
      HEAT_2  12 pdpevrraairaLg......rignpealpaLvellededpavRraaaeaLgai.....gdpealpaLkellddddddvvReaAa 84 
                  d +  r+a+ra+g      +  +++++++L++l++++  +v ++a+  +  i     g +  +p L+++ d+ d++  R+a +
  EEA18991.1 366 VDMDFVRRAVRAIGqtaikiESSSERCVNTLLDLINTKVNYVVQEAIVVIRDIfrkypGYENIIPTLCKCIDELDEPNARAALI 449
                 55566799******777755556779************************988777778899*********9999999898866 PP

  == domain 6  score: 7.5 bits;  conditional E-value: 0.003
      HEAT_2   1 ldaLlqalendpdpevrraairaLgrignp.....ealpaLvellededpavRraaaeaLgai..gdpe.....alpaLkellddddddvvReaA 83 
                 +++L++ + +  +p+ r+a i+  g+++++     ++l+ +ve  + e + ++ ++ +a +++  ++pe     + ++L+++ ++ d++++R +A
  EEA18991.1 429 IPTLCKCIDELDEPNARAALIWIVGEYAEKisnagDILAGFVEGFNEEFTQTQLQILTAVVKLflKRPEkaqglVQKVLQAATKENDNPDIRDRA 523
                 57899999888999***********888877777899999999999999***********98866444433443445555555555568888776 PP

  == domain 7  score: -1.7 bits;  conditional E-value: 2.2
      HEAT_2  36 Lvelled..edpavRraaaeaL 55 
                 + e l++  e+p   +aaa a 
  EEA18991.1 599 IEEQLQNarENPLAAAAAAAAV 620
                 3334433224444444444444 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.3   0.0    0.0074        13       5      26 ..      94     115 ..      90     116 .. 0.81
   2 !   15.2   0.0   1.1e-05     0.019       5      27 ..     129     151 ..     127     154 .. 0.89
   3 !   17.1   0.0   2.6e-06    0.0047       1      29 [.     164     192 ..     164     194 .. 0.93
   4 ?   -2.7   0.0         6   1.1e+04       9      22 ..     251     264 ..     245     266 .. 0.78
   5 ?    1.7   0.0      0.22     4e+02       3      29 ..     287     312 ..     286     314 .. 0.80
   6 ?    4.2   0.0     0.037        66       1      30 [.     428     458 ..     428     459 .. 0.89

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0074
                 HHHHHT-SSHHHHHHHHHHHHH CS
        HEAT   5 llkllsDpspeVReaAakaLga 26 
                 +++  +Dp+p +R+ A++++g 
  EEA18991.1  94 FVQDSKDPNPLIRALAIRTMGC 115
                 555579************9985 PP

  == domain 2  score: 15.2 bits;  conditional E-value: 1.1e-05
                 HHHHHT-SSHHHHHHHHHHHHHH CS
        HEAT   5 llkllsDpspeVReaAakaLgal 27 
                 l k l+D+sp VR++Aa ++++l
  EEA18991.1 129 LRKTLKDESPYVRKTAAICVAKL 151
                 7789***************9988 PP

  == domain 3  score: 17.1 bits;  conditional E-value: 2.6e-06
                 HHHHHHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgalae 29 
                 +l +l++l+ Dp+p V ++A+ aL++++e
  EEA18991.1 164 FLETLQELIGDPNPMVVANAVTALAEISE 192
                 5889***********************98 PP

  == domain 4  score: -2.7 bits;  conditional E-value: 6
                 HT-SSHHHHHHHHH CS
        HEAT   9 lsDpspeVReaAak 22 
                  ++ +++V  aA+k
  EEA18991.1 251 FQHVNASVVLAAVK 264
                 57889999999997 PP

  == domain 5  score: 1.7 bits;  conditional E-value: 0.22
                 HHHHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   3 PlllkllsDpspeVReaAakaLgalae 29 
                 P+l++ l +++peV + A++++  l++
  EEA18991.1 287 PPLVT-LVSSAPEVQYVALRNIDLLLQ 312
                 56666.5699**********9977765 PP

  == domain 6  score: 4.2 bits;  conditional E-value: 0.037
                 HHHHHHHHHT-..SSHHHHHHHHHHHHHHHHC CS
        HEAT   1 llPlllkllsD..pspeVReaAakaLgalaev 30 
                 ++P+l+k+  D  ++p+ R+a ++ +g+ ae+
  EEA18991.1 428 IIPTLCKC-IDelDEPNARAALIWIVGEYAEK 458
                 79*****7.5779*************999886 PP

>> Arm  Armadillo/beta-catenin-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.79   1.4e+03      15      33 ..     127     145 ..     127     148 .. 0.93
   2 !   10.7   0.0   0.00024      0.43       4      40 ..     155     191 ..     153     192 .. 0.91
   3 ?   -0.6   0.0      0.84   1.5e+03      15      32 ..     287     303 ..     286     305 .. 0.72
   4 ?    2.1   0.0      0.12   2.2e+02      13      37 ..     392     416 ..     388     420 .. 0.84
   5 ?    2.2   0.0      0.11   2.1e+02      12      32 ..     427     447 ..     426     448 .. 0.80

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.79
                 HHHHHHTTTSSHHHHHHHH CS
         Arm  15 ppLvrLLssedeevqeeAa 33 
                 +pL + L++e++ v++ Aa
  EEA18991.1 127 EPLRKTLKDESPYVRKTAA 145
                 59999***********998 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 0.00024
                 HHHHHHHTTHHHHHHHHTTTSSHHHHHHHHHHHHHHT CS
         Arm   4 nkdavieaGavppLvrLLssedeevqeeAawALsNLa 40 
                 n+ +  e G ++ L +L+ +++++v+ +A++AL+ ++
  EEA18991.1 155 NRTMCLENGFLETLQELIGDPNPMVVANAVTALAEIS 191
                 7778889999999********************9997 PP

  == domain 3  score: -0.6 bits;  conditional E-value: 0.84
                 HHHHHHTTTSSHHHHHHH CS
         Arm  15 ppLvrLLssedeevqeeA 32 
                 ppLv+L s   +evq +A
  EEA18991.1 287 PPLVTLVS-SAPEVQYVA 303
                 89999999.666666655 PP

  == domain 4  score: 2.1 bits;  conditional E-value: 0.12
                 HHHHHHHHTTTSSHHHHHHHHHHHH CS
         Arm  13 avppLvrLLssedeevqeeAawALs 37 
                 +v  L++L++++   v++eA   ++
  EEA18991.1 392 CVNTLLDLINTKVNYVVQEAIVVIR 416
                 899*******999999999987776 PP

  == domain 5  score: 2.2 bits;  conditional E-value: 0.11
                 THHHHHHHHTTTSSHHHHHHH CS
         Arm  12 GavppLvrLLssedeevqeeA 32 
                 +++p L+++++  de   ++A
  EEA18991.1 427 NIIPTLCKCIDELDEPNARAA 447
                 89*********8888666655 PP

>> CLASP_N  CLASP N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.0     0.012        21     174     205 ..     122     153 ..     112     158 .. 0.69
   2 ?    2.3   0.0     0.057     1e+02     178     211 ..     165     198 ..     155     214 .. 0.70
   3 !    5.7   0.0    0.0052       9.4      86     134 ..     383     432 ..     368     450 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.012
     CLASP_N 174 ldliekslkkgleDanptVRetaRstfweffk 205
                 +d + + l+k l+D +p VR+ta  ++ ++f+
  EEA18991.1 122 VDYMGEPLRKTLKDESPYVRKTAAICVAKLFD 153
                 45555667777777777777777777766665 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.057
     CLASP_N 178 ekslkkgleDanptVRetaRstfweffkvwPsrA 211
                  ++l++++ D+np V  +a +++ e+++ +P+  
  EEA18991.1 165 LETLQELIGDPNPMVVANAVTALAEISESAPETK 198
                 4567777777777777777777777777777654 PP

  == domain 3  score: 5.7 bits;  conditional E-value: 0.0052
     CLASP_N  86 eqldpmveillptLlkllgdtKkiisqnanqalaallsnas.fsprilqv 134
                  ++++++e+ ++tLl+l+  + + + q+a +++ +++++ + +++ i ++
  EEA18991.1 383 IKIESSSERCVNTLLDLINTKVNYVVQEAIVVIRDIFRKYPgYENIIPTL 432
                 459999*******************************9998444444555 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0      0.29   5.2e+02      38      54 ..      99     115 ..      76     116 .. 0.83
   2 !   10.3   0.0   0.00043      0.77       4      54 ..     106     150 ..     103     151 .. 0.77
   3 ?    5.3   0.0     0.016        28      29      55 .]     164     190 ..     158     190 .. 0.88
   4 ?   -1.5   0.0       2.2   3.9e+03      28      53 ..     427     453 ..     423     455 .. 0.76
   5 ?   -3.2   0.1       7.2   1.3e+04      22      34 ..     554     566 ..     549     569 .. 0.78
   6 ?   -3.1   1.3       7.1   1.3e+04       6      23 ..     615     629 ..     609     632 .. 0.60

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.29
     HEAT_EZ  38 nddsdeVRaaAagaLgn 54 
                 +d+++++Ra A+++ g 
  EEA18991.1  99 KDPNPLIRALAIRTMGC 115
                 79999*******99875 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00043
     HEAT_EZ   4 RraAawaLGrlaggepellqplvpeilpaLlalLnddsdeVRaaAagaLgn 54 
                 R+ A++++G++       + ++v+ +  +L ++L+d+s+ VR++Aa++ ++
  EEA18991.1 106 RALAIRTMGCIR------VDKMVDYMGEPLRKTLKDESPYVRKTAAICVAK 150
                 555666666555......666778888899****************99776 PP

  == domain 3  score: 5.3 bits;  conditional E-value: 0.016
     HEAT_EZ  29 ilpaLlalLnddsdeVRaaAagaLgnl 55 
                  l  L  l  d++++V a+A+ aL+ +
  EEA18991.1 164 FLETLQELIGDPNPMVVANAVTALAEI 190
                 5778999*****************876 PP

  == domain 4  score: -1.5 bits;  conditional E-value: 2.2
     HEAT_EZ  28 eilpaLlalLnd.dsdeVRaaAagaLg 53 
                  i+p L+++    d+++ Raa ++  g
  EEA18991.1 427 NIIPTLCKCIDElDEPNARAALIWIVG 453
                 689999999855588888998888665 PP

  == domain 5  score: -3.2 bits;  conditional E-value: 7.2
     HEAT_EZ  22 lqplvpeilpaLl 34 
                 +q+l p++l++Ll
  EEA18991.1 554 IQTLPPALLDQLL 566
                 6788888888887 PP

  == domain 6  score: -3.1 bits;  conditional E-value: 7.1
     HEAT_EZ   6 aAawaLGrlaggepellq 23 
                 aAa+a++   g  p++++
  EEA18991.1 615 AAAAAVS---GATPPAQS 629
                 4444554...77777665 PP

>> RTP1_C1  Required for nuclear transport of RNA pol II C-terminus 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       2.5   4.4e+03       5      23 ..      95     113 ..      92     120 .. 0.85
   2 !    9.4   0.0   0.00062       1.1       6      74 ..     131     197 ..     127     204 .. 0.94
   3 ?   -1.4   0.0       1.4   2.5e+03      26      65 ..     229     267 ..     205     298 .. 0.70
   4 ?    1.9   0.0      0.14   2.5e+02      36      84 ..     387     437 ..     371     465 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 2.5
     RTP1_C1   5 lkdlqdpllpvrahglvlL 23 
                 ++d +dp + +ra +++++
  EEA18991.1  95 VQDSKDPNPLIRALAIRTM 113
                 67889*********99987 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.00062
     RTP1_C1   6 kdlqdpllpvrahglvlLrkliekkskeavldiekilkllleaLkdedsYvYLnaikgLvaLadvfpee 74 
                 k l+d+ + vr  + +  +kl+  ++  ++   +  l++l+e + d+++ v  na+ +L+++ +  pe+
  EEA18991.1 131 KTLKDESPYVRKTAAICVAKLFDLNR--TMCLENGFLETLQELIGDPNPMVVANAVTALAEISESAPET 197
                 6899********************99..9**********************************999875 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 1.4
     RTP1_C1  26 liekkskeavldiekilkllleaLkdedsYvYLnaikgLv 65 
                 l+e + +++v+d+e+i + ++ + ++ +  v L+a+k++ 
  EEA18991.1 229 LAEFR-TTDVKDAEHICERVVPQFQHVNASVVLAAVKVVF 267
                 33333.3588889999999999999998888899988764 PP

  == domain 4  score: 1.9 bits;  conditional E-value: 0.14
     RTP1_C1  36 ldiekilkllleaLkdedsYvYLnaikgLvaLadvfp..eevlklLleeye 84 
                 ++ e+ +++ll+ ++ +  Yv  +ai ++  +  ++p  e+++++L++   
  EEA18991.1 387 SSSERCVNTLLDLINTKVNYVVQEAIVVIRDIFRKYPgyENIIPTLCKCID 437
                 5678889999999**********************9855789999999873 PP

>> DUF2817  Protein of unknown function (DUF2817)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   4.2e-05     0.075       5      73 ..     603     670 ..     600     682 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 4.2e-05
     DUF2817   5 YaeaRekflaaAeaagaelesyvlpekgregeeLaiDvarlgpadakklLvltsGthGveGfaGSavqv 73 
                  ++aRe+ laaA+aa+a  + ++ p + +++ e  +D+ + g+a a++     sG+ G+eG+aG  + +
  EEA18991.1 603 LQNARENPLAAAAAAAAV-SGATPPAQSQANAENLLDIDFDGSAPASAQKEPPSGMSGLEGLAGTPMRT 670
                 5789***99999877665.55555555788888889999999999999999*************98876 PP

>> Sec7_N  Guanine nucleotide exchange factor in Golgi transport N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   0.7   0.00076       1.4      55     115 ..     275     333 ..     224     374 .. 0.75
   2 ?   -3.6   0.0         5   8.9e+03      42      67 ..     483     508 ..     476     519 .. 0.70

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00076
      Sec7_N  55 pellqllkqklcplLlknlsespsfpvferslrivllLlkkfrseLktEievflsllilil 115
                 +el     +k+ p L++++  s++++v  ++lr + lLl+k+ + L++E+ vf+   + + 
  EEA18991.1 275 SELATSYLKKMAPPLVTLV--SSAPEVQYVALRNIDLLLQKQPDILNKELRVFFCKYNDPP 333
                 4555555556677777777..7888999999**********************97776655 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 5
      Sec7_N  42 svlsnhgdvfrkhpellqllkqklcp 67 
                 ++l+   ++f k+pe  q l qk+++
  EEA18991.1 483 QILTAVVKLFLKRPEKAQGLVQKVLQ 508
                 46666677777777776666666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (762 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       803  (0.0447878); expected 358.6 (0.02)
Passed bias filter:                      625  (0.0348597); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.76u 0.32s 00:00:01.08 Elapsed: 00:00:00.47
# Mc/sec: 4825.00
//
Query:       EEA18992.1  [L=403]
Description: tubulin-specific chaperone c, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.9e-34  115.8   1.5    1.4e-33  115.2   1.5    1.3  1  TBCC          Tubulin binding cofactor C
    3.9e-09   37.0   0.1      7e-09   36.1   0.1    1.4  1  TBCC_N        Tubulin-specific chaperone C N-terminal domain
  ------ inclusion threshold ------
      0.044   14.0   0.0      0.065   13.4   0.0    1.3  1  CENP-L        Kinetochore complex Sim4 subunit Fta1
      0.057   13.5   0.3       0.64   10.1   0.0    2.3  2  F_actin_bind  F-actin binding


Domain annotation for each model (and alignments):
>> TBCC  Tubulin binding cofactor C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.2   1.5   3.1e-37   1.4e-33       3     120 .]     238     354 ..     236     354 .. 0.95

  Alignments for each domain:
  == domain 1  score: 115.2 bits;  conditional E-value: 3.1e-37
                 EEEE-S-BS-EEEE......-S--S-EEEES-BS-EEE----SS-EEEES-BS-EEE---SEEEEES-BS-EEE---SSEEEEES-BSEEEE------T CS
        TBCC   3 svkisnlsdctiyl......ldplssvtiddcknctivlgpvsgsvfiedcenctivvacrqlrihdctnvdvylltksrPiiedskgirfapynlsyp 95 
                 +++i++l++c++++       +p++s+ti+ +k++ i++g+v+g+++i+++e++++vv+crq+r+h+c +vdvyl+++s+Piied+++irf +++ +y+
  EEA18992.1 238 PASITSLRHCVVDMsipttdGKPFASLTIKGVKESLIICGQVDGPAHITNVEHSVVVVSCRQFRMHNCADVDVYLSCTSNPIIEDCTRIRFSRIPKTYA 336
                 5799***************99*****************************************************************************8 PP

                 TSHHHHHHHT--SS---.-S-EE-- CS
        TBCC  96 eleehlkkagldpennnlwsevddf 120
                   +         p+n ++w++v+df
  EEA18992.1 337 LDK-------NHPDNSDKWDQVEDF 354
                 886.......56888888*****98 PP

>> TBCC_N  Tubulin-specific chaperone C N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.1   0.1   1.6e-12     7e-09      31     115 ..      27     112 ..       8     113 .. 0.91

  Alignments for each domain:
  == domain 1  score: 36.1 bits;  conditional E-value: 1.6e-12
      TBCC_N  31 vdsFlkaFteekaaieellesve.esadksklkqkldeitaeiqeLqkllaessmfLpsYdlrsaqealskLkesleeareellPk 115
                  d F + F+ee  a++e+++++   s+ + ++++  d   a i++L + + ++s ++p+Yd r + ea++ L+++l e+r++++P+
  EEA18992.1  27 KDRFFRYFQEEITALQEQMDRLAdTSLVAGERSDATDYCLAGIARLSNEVKDASSYIPTYDQRIYAEAIKALQDKLSETRATIQPR 112
                 4679999***************9999999********************************************************8 PP

>> CENP-L  Kinetochore complex Sim4 subunit Fta1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   1.5e-05     0.065      69     154 ..     158     303 ..      91     306 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 1.5e-05
      CENP-L  69 qltlsFa.vppeapglktlditipaedlreflragedsseeddttndeesqpFleaLasylkkhlalnld............................. 137
                 +lt  +a +p +  +  +l  +i++++ ++fl++g+ds++ ++++nd ++++F +a +  +++h +l++                              
  EEA18992.1 158 NLTPLYAsTPVNDIETPQLRPEIAPTSSATFLDEGKDSAALEKKSNDIRRPSFSNASSVAVDQHYGLHIMlpasassaavpasitslrhcvvdmsiptt 256
                 5555554356667777789999******************99***************************999999999999999999999999999999 PP

      CENP-L 138 ..............................hpavrvskvscgafvls 154
                                               + +  v+ vsc  f ++
  EEA18992.1 257 dgkpfasltikgvkesliicgqvdgpahitNVEHSVVVVSCRQFRMH 303
                 99888888888888888888888888887777777777888877776 PP

>> F_actin_bind  F-actin binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.1     0.054   2.4e+02      63      89 ..      33      61 ..      20      83 .. 0.62
   2 ?   10.1   0.0   0.00014      0.64      14      66 ..      71     119 ..      60     130 .. 0.77

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.054
  F_actin_bind 63 aFrellsrLesqsreLr..savgsknsse 89
                   F+e+++ L+ q++ L   s v+++ s +
    EEA18992.1 33 YFQEEITALQEQMDRLAdtSLVAGERSDA 61
                  499************99863333322222 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00014
  F_actin_bind  14 lleaalsnlkesvsssqesaqllqlldkvenlhssCsgyvdsipphakFaFre 66 
                    l+++++ +++ ++    +    + ++++++l+++ s+   +i+p+akF+F+ 
    EEA18992.1  71 RLSNEVKDASSYIP----TYDQRIYAEAIKALQDKLSETRATIQPRAKFSFKT 119
                   45555555555544....4447889**************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (403 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       675  (0.0376485); expected 358.6 (0.02)
Passed bias filter:                      575  (0.0320709); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.57u 0.31s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 2604.41
//
Query:       EEA18993.1  [L=595]
Description: tripeptidyl peptidase SED3 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.9e-35  120.1   0.1    6.2e-34  117.3   0.1    2.3  2  Pro-kuma_activ  Pro-kumamolisin, activation domain
    5.8e-08   32.3   0.1      1e-07   31.6   0.1    1.3  1  Peptidase_S8    Subtilase family


Domain annotation for each model (and alignments):
>> Pro-kuma_activ  Pro-kumamolisin, activation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.3   0.1   6.9e-38   6.2e-34       2     142 .]      40     180 ..      39     180 .. 0.99
   2 ?   -1.0   0.0      0.21   1.9e+03     115     131 ..     199     215 ..     187     225 .. 0.82

  Alignments for each domain:
  == domain 1  score: 117.3 bits;  conditional E-value: 6.9e-38
  Pro-kuma_activ   2 gwtkrgraasstllpvrigLkqnnlekledflmdvsdpkspnygkhltaeevaelfapseeaidaVrnwLessgiaasrhsdtkgwiafsatvaq 96 
                     gw++  r ++s+l+++r++++q  + ++e+++ ++++p+++ ygkh++++ev++ ++ps e +daV +wL+s+g++++ ++ +++w +f ++ +q
      EEA18993.1  40 GWVQGPRPSPSMLMQFRLAMTQPRAGEFEQHVINIATPGHKMYGKHMKRDEVKAFMQPSAEVSDAVVSWLKSEGVSDNLMEVDSDWAKFIVPLHQ 134
                     89********************************************************************************************* PP

  Pro-kuma_activ  97 verllktsfeaYshkkgssslarcdeyslPealknyvdyihptdnf 142
                     +e++l+t+f+ ++ +++  +++r+ +ys+P++++++v++i+pt++f
      EEA18993.1 135 AEKMLNTTFYIFHDEDKTVFRVRTLQYSVPREIHQHVRLIQPTTHF 180
                     *************99****************************997 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.21
  Pro-kuma_activ 115 sslarcdeyslPealkn 131
                        a+c++ ++P++l++
      EEA18993.1 199 AAQANCNTLITPDCLRD 215
                     57899*********986 PP

>> Peptidase_S8  Subtilase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.6   0.1   1.1e-11     1e-07     120     264 ..     342     515 ..     315     527 .. 0.77

  Alignments for each domain:
  == domain 1  score: 31.6 bits;  conditional E-value: 1.1e-11
                   CT-SEEEE-EE.SCETTCHHCHHHHHHHHHHHH.CCT-EEEEE--SS-T-HH......EEE-TTCEEC.....TTTSTTCEEEEEES.......... CS
                   xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxx.....xxxxxxxxxxxxxx.......... RF
  Peptidase_S8 120 dkvdvinmslg.estslpktgrsiealainravnkkgvlvviSaGNngktgs......slqagspvgt.....pstsknvitvgayt.......... 194
                   d + v++ s+g ++  lp++++++   ++ ++   +gv +++S+G +g  +       +  +           p+++  v++vg++           
    EEA18993.1 342 DLPAVLSTSYGeNEQTLPESYTNTTCSLFAQLG-ARGVSIIFSSGDEGVGQAcltndgTNRT-----RfnpiyPASCPFVTSVGGTYqinperavaf 432
                   344499*****5455566666665544666666.68************66667555432222.....222344999999****99999********* PP

                   ..............TTSSB-TT.--B-TT.......-EEEE-S-CCCCCCCCCHHHTTTHH..EEEE-SHHHCHHHHHHHHHHHHH.H CS
                   ..............xxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxx.x RF
  Peptidase_S8 195 ..............tegkiapf.SsrGpssdgklkpdivapGgnivstwsrqsnnsaglss..yqsmsGTSmAsPnaagaaAllls.a 264
                                 +e+ +a++ S  G  ++     d+  pGg +++++s q+++   +    + ++ GTS+++P  a+++A l s +
    EEA18993.1 433 ssggfserfprpsyQEDAVASYlSILGDRWE-----DLYNPGGRGFPDVSAQAHAYLVRDHgsFIQVDGTSASAPTFAAIIADLNSvR 515
                   **************777776662667****9.....*****************7665555599*******************888744 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (595 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       446  (0.0248759); expected 358.6 (0.02)
Passed bias filter:                      425  (0.0237046); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.27s 00:00:00.89 Elapsed: 00:00:00.46
# Mc/sec: 3890.34
//
Query:       EEA18994.1  [L=134]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.1e-07   28.7   0.0    1.6e-06   27.8   0.0    1.5  1  Cupin_2   Cupin domain
    0.00011   21.8   0.0    0.00018   21.1   0.0    1.3  1  Cupin_3   Protein of unknown function (DUF861)


Domain annotation for each model (and alignments):
>> Cupin_2  Cupin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0   1.7e-10   1.6e-06       3      58 ..      70     124 ..      68     130 .. 0.84

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 1.7e-10
                 EEEETTEEEEEECSSSEEEEEEEEESEEEEEEC.TEEEEEETTEEEEE-TT-EEEEE CS
     Cupin_2   3 velppGesapshrHpgedeffyVleGegeltvd.geeveleaGdsvyfpagtpHrfr 58 
                 ++++p +++++hr      +++V+eGe+e+t+d ge  +l+ Gds++  a t H++ 
  EEA18994.1  70 ISMAPRAESGMHRTMTL-DTIVVVEGEVEVTLDsGEMRILKSGDSLVQRA-TMHKWM 124
                 67999999999998888.*************8879**********98777.445554 PP

>> Cupin_3  Protein of unknown function (DUF861)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.1   0.0     2e-08   0.00018      28      60 ..      88     120 ..      76     128 .. 0.87

  Alignments for each domain:
  == domain 1  score: 21.1 bits;  conditional E-value: 2e-08
                 EEEEEECEEEEEETTTEEEEEETTEEEEE-TTE CS
     Cupin_3  28 fcyileGevkvtpeggetvelraGDlvvlpkgl 60 
                 ++ ++eGev+vt ++ge + l+ GD++v ++ +
  EEA18994.1  88 TIVVVEGEVEVTLDSGEMRILKSGDSLVQRATM 120
                 679************************988766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (134 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       274  (0.0152825); expected 358.6 (0.02)
Passed bias filter:                      248  (0.0138323); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.41u 0.27s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 933.56
//
Query:       EEA18995.1  [L=234]
Description: hypothetical protein PMAA_012640 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
     0.0038   16.8   0.0     0.0097   15.5   0.0    1.6  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
     0.0064   16.0   0.0       0.01   15.3   0.0    1.3  1  adh_short     short chain dehydrogenase
  ------ inclusion threshold ------
      0.027   14.1   0.0       0.04   13.5   0.0    1.2  1  PARP          Poly(ADP-ribose) polymerase catalytic domain


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   1.6e-06    0.0097      84     170 ..      87     175 ..      73     210 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1.6e-06
                   SS-GGGH-HHHHHHHHHHHTHHHHHHHHHHHH.HCTSCCEEEEEEEGGGTSB.STTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEE CS
  adh_short_C2  84 kgpfletsreefdraldvnlyslfllakaalp.lmkeggsivnlssvgaerv.vpnynaygaaKaalealtrylAvelgpkgiRvNavs 170
                    +p+ ++s e++++++ vn+   f   +a +p l++++    + +   ++++ +   +a +++ +al +++  ++++  + ++R N + 
    EEA18995.1  87 ATPLQDISTEDLRQIMTVNFEWNFWAYRATIPyLLNQNDTRSTWTLCTGSQGdLGARAAPAMTQGALYSMANVACRDNYKTNVRFNEIY 175
                   57999***************************8778775555555555555537777799**************************986 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   1.7e-06      0.01      86     179 ..      83     176 ..      76     192 .. 0.88

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 1.7e-06
                 -SS--SSGGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE CS
   adh_short  86 GitgsgpfselseeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaP 179
                 G    +p +++s e+ ++++ vN+   f++ ra +p++l+q+  r   +  + ++  +   aa + + +a+ ++++ + ++  +t++r n ++ 
  EEA18995.1  83 GGYTATPLQDISTEDLRQIMTVNFEWNFWAYRATIPYLLNQNDTRSTWTLCTGSQGDLGARAAPAMTQGALYSMANVACRDNYKTNVRFNEIYL 176
                 4467899********************************9999999988888888889999999999999999999999999999999999876 PP

>> PARP  Poly(ADP-ribose) polymerase catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   6.7e-06      0.04      17      68 ..      32      84 ..      19      96 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 6.7e-06
                TTTT.EEEEEEEEEEEEETTHHHHCGCCGGSS-EEEEEEEE-GGGHHHHHHH- CS
        PARP 17 stha.yklkileifrvqregeaerfqekkklrnrrlLfHGsrltnvasilsqG 68
                + h   ++ +  i  + + g+ + fq   + +  ++LfHGsr ++v+++   G
  EEA18995.1 32 NDHIcSENGVRGIVDLVKAGKLPAFQHVYAAGLSIYLFHGSRAESVLRLAGGG 84
                44444688899999999999*************************99876666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (234 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       315  (0.0175693); expected 358.6 (0.02)
Passed bias filter:                      297  (0.0165653); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.41u 0.25s 00:00:00.65 Elapsed: 00:00:00.40
# Mc/sec: 1751.16
//
Query:       EEA18996.1  [L=295]
Description: proteasome regulatory particle subunit (RpnL), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.8e-18   66.9   0.0    3.4e-18   66.0   0.0    1.4  1  CSN8_PSD8_EIF3K  CSN8/PSMD8/EIF3K family
    0.00019   21.0   0.0    0.00026   20.5   0.0    1.2  1  SAC3_GANP        SAC3/GANP family


Domain annotation for each model (and alignments):
>> CSN8_PSD8_EIF3K  CSN8/PSMD8/EIF3K family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.0   0.0   3.8e-22   3.4e-18       4     136 ..     107     246 ..     105     254 .. 0.89

  Alignments for each domain:
  == domain 1  score: 66.0 bits;  conditional E-value: 3.8e-22
  CSN8_PSD8_EIF3K   4 aelytniLlkaLtqndladfrlllkrlpaaiqqs......deeiqklltLetlLeeanyakfwstlksdd.lsadltadvagleelvReeiakl 90 
                      +++++++Ll++L++ d+++f++ l+ l  + + +      d+ i++ ++Le+ L+e++y k+w + ks + + +d+  +   l  ++R+eia +
       EEA18996.1 107 SKITGLYLLLLLSSGDTSQFHTVLEGLIVEASLEgrsvedDPFIKYPVELERSLMEGSYDKVWRATKSSEvPTEDFGLFSNVLVGTIRREIADC 200
                      6799*********************887777766789999************************999876245688888888999********* PP

  CSN8_PSD8_EIF3K  91 vgkaYesIsadvlaelLglssdeelekfvkevgWeldaatvivpfn 136
                       + aY+s+ +++++ lL l+s+ ++  f+ e+gW+l + +  +p++
       EEA18996.1 201 SETAYQSLPISNAKDLLFLESEGAVVAFAQECGWTLKDGRIYFPAQ 246
                      ********************999*************7766666654 PP

>> SAC3_GANP  SAC3/GANP family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5   0.0   2.9e-08   0.00026     146     292 ..      74     237 ..      55     238 .. 0.80

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 2.9e-08
                 HHHHHHHHHHHHHHHH...........---TTHHHHHHHHHHHTTT-......HHHHHH..HC.TS.-HHHHTSHHHHHHHHHHHHH--TTHHHHHHHH CS
   SAC3_GANP 146 LqkclqsLlelYddlrkkk........eelpneaefrayylLlnlrd......pdilre..vq.el.pseilkspevqlalklvaalqennyvrffklv 226
                 + + +q+L  +Yd  r+++        ++  ++++++++ylLl l++      +++l+   v+ +l  +++ ++p +++ ++l + l+e+ y ++++ +
  EEA18996.1  74 FIRYYQQLQPFYDFERDTSsksaskeaSKTSQRSKITGLYLLLLLSSgdtsqfHTVLEGliVEaSLeGRSVEDDPFIKYPVELERSLMEGSYDKVWRAT 172
                 5567889999998886555666777778889999******9999955444444445544222223446788999************************* PP

                 T..TS-HHHHHHH.GGGHHHHHHHHHHHHHHHS-TT---EEHHHHHHHTT-SSHHHHHHHHHHTT--EE CS
   SAC3_GANP 227 k..evsylqacll.erhfnevRrkalkalsraykskskkvpleeLaelLlfddeeeaeefceayglevs 292
                 k  ev+     l+ ++ + ++Rr++ ++  +ay    +++p+++ ++lL++++e  +++f +++g +++
  EEA18996.1 173 KssEVPTEDFGLFsNVLVGTIRREIADCSETAY----QSLPISNAKDLLFLESEGAVVAFAQECGWTLK 237
                 *9888777665551567789*************....89**************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (295 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       531  (0.0296168); expected 358.6 (0.02)
Passed bias filter:                      456  (0.0254337); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.44
# Mc/sec: 2032.87
//
Query:       EEA18997.1  [L=465]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.014   16.3   0.3         24    6.0   0.0    3.8  3  WD40      WD domain, G-beta repeat


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.0    0.0014        24      13      37 ..     105     130 ..      96     131 .. 0.82
   2 ?    4.0   0.0    0.0059     1e+02      10      37 ..     302     337 ..     294     338 .. 0.73
   3 ?    1.6   0.1     0.033   5.9e+02      25      38 .]     449     462 ..     424     462 .. 0.75

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.0014
                 EEEEEEETTSSEE..EEEETTSEEEEE CS
        WD40  13 vtslafspdgawl..asGsdDgtvriW 37 
                 v +++f+p  + +  ++Gs Dg++ ++
  EEA18997.1 105 VFDIKFHPIRQHIlgVAGS-DGSISVY 130
                 6788899999998344899.****998 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.0059
                 S..SSEEEEEEETTSSE......EEEEETTSEEEEE CS
        WD40  10 H..ssvtslafspdgaw......lasGsdDgtvriW 37 
                 H  ++vts+   p +++      +++Gs+D  +r++
  EEA18997.1 302 HtaGGVTSILPLPISHLvkkapiILTGSYDEYIRVY 337
                 55344888876666666666665789********97 PP

  == domain 3  score: 1.6 bits;  conditional E-value: 0.033
                 EEEEETTSEEEEEE CS
        WD40  25 lasGsdDgtvriWd 38 
                 ++s+ +D+ + +W+
  EEA18997.1 449 VSSSFYDKRLCLWK 462
                 334558*******6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (465 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       374  (0.0208601); expected 358.6 (0.02)
Passed bias filter:                      339  (0.0189079); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.24s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 3293.28
//
Query:       EEA18998.1  [L=291]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.2e-26   90.5   0.0    1.3e-25   89.3   0.0    1.7  1  Vps51     Vps51/Vps67
  ------ inclusion threshold ------
      0.059   13.5   0.0       0.17   12.0   0.0    1.7  2  COG5      Golgi transport complex subunit 5
      0.074   11.7   0.0       0.12   11.0   0.0    1.4  1  Dor1      Dor1-like family


Domain annotation for each model (and alignments):
>> Vps51  Vps51/Vps67
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.3   0.0   2.2e-29   1.3e-25       1      86 [.     108     196 ..     108     197 .. 0.94

  Alignments for each domain:
  == domain 1  score: 89.3 bits;  conditional E-value: 2.2e-29
       Vps51   1 ldspdfdaeayvrellakstlkellkveasllseiraldselkalVydnYskLisasdtIrkmksem...dkldqklselkqaiskiae 86 
                 ldsp+fda++y+++lla+s+l+++lk e++l+ +ir+ld e+kalVydnYskLi a +tI +m+++m       +++++l++a+  +ae
  EEA18998.1 108 LDSPKFDAQQYIDQLLATSSLSTVLKAENTLVGDIRTLDGERKALVYDNYSKLIRAVETIGTMRRSMeerGAPLTMTKTLGPAVAFVAE 196
                 79*****************************************************************6665688999999999988877 PP

>> COG5  Golgi transport complex subunit 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0         1   6.1e+03      53     103 ..      19      71 ..      17      75 .. 0.72
   2 ?   12.0   0.0   2.9e-05      0.17       5      71 ..     110     171 ..     106     178 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1
                 XXXXXXXXXXXXXXXXXXXX..XXXXXXXXXXXXXXXXXXXX-TTHHHHHHHH CS
        COG5  53 itsnhleLlehlskskslss..vlselksslesLsasyerlkskvlepyeeae 103
                 i+s++++L ++++ ++s+s+  +++++ +s+++  +  +r ++  l+ y++++
  EEA18998.1  19 ISSRQPSLDNNVNPNLSASGlgINNNVGPSIARAVSPAQRRNRAALRDYYNIK 71 
                 66777888888888888887777788888887777777777777777777665 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 2.9e-05
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        COG5   5 epdFdpksfanallkatnnnddteldlstplkrlnydiqeldkrlrqlitsnhleLlehlsksksls 71 
                 +p Fd++++  +ll      +++ + +  + ++l  di+ ld + + l+ +n+++L+  ++++ + +
  EEA18998.1 110 SPKFDAQQYIDQLLA-----TSSLSTVLKAENTLVGDIRTLDGERKALVYDNYSKLIRAVETIGTMR 171
                 799************.....3333333344578999**********************999987765 PP

>> Dor1  Dor1-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0     2e-05      0.12       5      70 ..     124     206 ..     120     291 .] 0.68

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 2e-05
        Dor1   5 sskpleelekepelLaeeaeeilaqiqdLarknyktlidaaealeairqelediraqledLvlkl..................p 70 
                  ++ l    k  + L  ++++++ ++++L  +ny  li+a e + ++r+++e+ r    ++ + l                  +
  EEA18998.1 124 ATSSLSTVLKAENTLVGDIRTLDGERKALVYDNYSKLIRAVETIGTMRRSMEE-RGAPLTMTKTLgpavafvaetasglikegE 206
                 5667777778889999**********************************999.444344555555555666666655555552 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (291 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       619  (0.0345251); expected 358.6 (0.02)
Passed bias filter:                      408  (0.0227564); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.30s 00:00:00.80 Elapsed: 00:00:00.47
# Mc/sec: 1864.63
//
Query:       EEA18999.1  [L=247]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.8e-65  218.9   0.1      8e-65  218.6   0.1    1.0  1  RMI1_N    RecQ mediated genome instability protein
  ------ inclusion threshold ------
      0.049   14.0   0.1      0.094   13.1   0.1    1.4  1  NuiA      Nuclease A inhibitor-like protein


Domain annotation for each model (and alignments):
>> RMI1_N  RecQ mediated genome instability protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  218.6   0.1   8.9e-69     8e-65       2     217 .]      13     220 ..      12     220 .. 0.89

  Alignments for each domain:
  == domain 1  score: 218.6 bits;  conditional E-value: 8.9e-69
      RMI1_N   2 ksrkhlpvspeWleacvesleee.pnlplsallktvleqlLasDltes...tnsssvlpaniaeqrksesspalkgpvvvQvldiedigsSaysqleal 96 
                  ++k+lpvs++W++++++s++++ +++p+sal++t+l+++L++D+t++   +++s+vlp++i++   +e  ++++gpv+vQvldiedigsS++sq+e++
  EEA18999.1  13 LNTKSLPVSTAWISNFLASISQNqQRAPPSALAQTALFRILTTDFTKTlstSMPSTVLPREISDPSIKE--RRISGPVPVQVLDIEDIGSSMWSQVEKI 109
                 4567*****************99655**********************99988999******7755554..55************************** PP

      RMI1_N  97 eavergeetrgrevirt.esaaaasakadeenseekeeaqatsseskkrrmlkLeLtDg.gqkvkAiElkpikglsl.klaiGvKllLkggvkvrrGvl 192
                 e+verge++rgre++r+ +        +d+ n++ +++     ++++ +++++L+L+D+ g+k++A+E++ i+g+s+ kl+iG+Kl+Lk +++v rG++
  EEA18999.1 110 EQVERGETIRGREIVRNvN-------VDDADNNNASRS-----TPNTTNGPHRLILQDAaGTKIVALEYQDINGISIeKLSIGAKLVLK-DTVVSRGMA 195
                 *****************42.......222222222222.....456679****************************************.********* PP

      RMI1_N 193 LLepenvkvlGGeveeldkawkeer 217
                 LL+pe+v++lGG++e++d +w+++r
  EEA18999.1 196 LLTPETVTLLGGKIESWDTTWRQKR 220
                 **********************986 PP

>> NuiA  Nuclease A inhibitor-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.1   1.1e-05     0.094      36      95 ..       3      62 ..       1      65 [. 0.93

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.1e-05
                SSTTHHHHHHT-TTTSSCEEE-HHHHTTCTT--SSTS-HHHHHHHHHHHHHHHHHTTHSS CS
        NuiA 36 ltkekllketghpadtpvesveldeflrnalteeewyeeeekeeaqrfqtlvklLksnLt 95
                 t+e++  ++ ++++ pv+++ + +fl+++ ++++  ++ + ++++ f+ l + ++++L+
  EEA18999.1  3 STEEHIRAQLLNTKSLPVSTAWISNFLASISQNQQRAPPSALAQTALFRILTTDFTKTLS 62
                578999999999****************************************99999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (247 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       415  (0.0231469); expected 358.6 (0.02)
Passed bias filter:                      334  (0.018629); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1739.11
//
Query:       EEA19000.1  [L=1398]
Description: translation repressor/antiviral protein Ski3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.2e-27   92.9  44.7      0.021   14.9   0.1   16.0 16  TPR_2       Tetratricopeptide repeat
    8.9e-25   87.0  16.9    9.8e-06   26.0   0.2   11.9 12  TPR_19      Tetratricopeptide repeat
      2e-24   84.4  31.4      0.013   15.3   0.0   15.3 15  TPR_1       Tetratricopeptide repeat
    3.2e-23   80.0  25.6      0.056   13.7   0.1   13.9 13  TPR_8       Tetratricopeptide repeat
    5.7e-23   79.7  30.9     0.0042   17.8   0.0   16.5 15  TPR_14      Tetratricopeptide repeat
    3.5e-21   75.5  48.9    4.2e-05   24.1   0.2   13.3 15  TPR_16      Tetratricopeptide repeat
    1.3e-20   72.2  17.5       0.16   12.4   0.0   15.2 15  TPR_17      Tetratricopeptide repeat
    1.8e-13   50.5  44.2    1.7e-05   25.0   0.2   13.6 16  TPR_12      Tetratricopeptide repeat
    2.3e-13   49.2  18.1     0.0061   16.5   0.0   11.7 11  TPR_7       Tetratricopeptide repeat
    3.7e-13   48.9  19.6     0.0021   17.7   0.0    8.6  8  TPR_11      TPR repeat
    5.8e-09   36.1   7.0        1.2    9.4   0.0    7.5  7  ANAPC3      Anaphase-promoting complex, cyclosome, subunit 3
    9.2e-06   26.0  25.4       0.67   10.7   0.0   12.3 13  TPR_6       Tetratricopeptide repeat
    1.3e-05   25.3   5.5        3.9    8.4   0.2    7.9  6  TPR_4       Tetratricopeptide repeat
    0.00048   19.9   1.1        1.6    8.4   0.2    4.4  4  DUF2989     Protein of unknown function (DUF2989)
     0.0019   18.3   6.3        6.3    7.0   0.0    5.9  5  TPR_9       Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.012   15.7   0.0      0.047   13.8   0.0    2.0  1  TPR_22      Tetratricopeptide repeat
      0.017   14.7   0.5        4.9    6.8   0.0    3.1  3  HrpB1_HrpK  Bacterial type III secretion protein (HrpB1_HrpK)
      0.022   15.4   1.6        7.3    7.4   0.3    4.1  2  Sel1        Sel1 repeat
      0.046   13.6  14.1       0.66    9.9   0.0    7.8  8  TPR_10      Tetratricopeptide repeat
       0.11   12.6   4.0        8.9    6.4   0.0    5.0  4  DUF3856     Domain of Unknown Function (DUF3856)
       0.22   11.9  15.4          1    9.7   0.1    5.4  4  TPR_20      Tetratricopeptide repeat
       0.64   10.0   9.2        1.2    9.1   0.1    3.9  3  TerB        Tellurite resistance protein TerB
        1.4    8.6   4.7        3.1    7.5   0.1    3.5  3  DUF2225     Uncharacterized protein conserved in bacteria (DU


Domain annotation for each model (and alignments):
>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.0    0.0014       1.1       3      30 ..      39      66 ..      37      70 .. 0.88
   2 ?   -2.4   0.0       9.7   7.6e+03       5      22 ..      97     114 ..      94     117 .. 0.80
   3 ?    6.4   0.0     0.014        11       3      29 ..     346     372 ..     344     376 .. 0.88
   4 !   14.9   0.1   2.8e-05     0.021       3      34 .]     429     460 ..     427     460 .. 0.93
   5 ?   -2.2   0.0       8.1   6.3e+03       1      14 [.     503     516 ..     503     517 .. 0.84
   6 !    7.4   0.3    0.0066       5.2       3      31 ..     546     575 ..     544     577 .. 0.77
   7 !   12.3   0.0   0.00019      0.15       4      34 .]     626     656 ..     625     656 .. 0.94
   8 !   12.2   0.0   0.00019      0.15       4      31 ..     660     687 ..     658     690 .. 0.91
   9 !   12.5   0.0   0.00016      0.13       5      33 ..     703     731 ..     699     732 .. 0.94
  10 ?    0.1   0.0       1.5   1.2e+03      14      31 ..     753     770 ..     750     771 .. 0.86
  11 ?    0.5   0.5       1.1   8.7e+02       3      13 ..     877     887 ..     875     890 .. 0.85
  12 ?    6.1   0.1     0.017        14      17      31 ..     909     923 ..     903     926 .. 0.79
  13 ?    6.6   0.1     0.012       9.5       2      34 .]     961     993 ..     960     993 .. 0.92
  14 ?    4.1   0.0     0.075        59       2      28 ..     995    1021 ..     994    1025 .. 0.88
  15 !    8.6   0.3    0.0027       2.1       2      33 ..    1122    1153 ..    1121    1154 .. 0.88
  16 !    9.7   0.3    0.0012      0.97       3      33 ..    1171    1201 ..    1170    1202 .. 0.90

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0014
       TPR_2  3 alynlGlayyklgdyeeAleafekAlel 30
                a+  lGla  klg+++eA+  + +A ++
  EEA19000.1 39 AHVFLGLAQDKLGKPDEAESSYLAASRI 66
                7889******************999766 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 9.7
       TPR_2   5 ynlGlayyklgdyeeAle 22 
                  +lG++++++++ ++ l 
  EEA19000.1  97 LRLGQILAENDERDRSLY 114
                 589*****9999988775 PP

  == domain 3  score: 6.4 bits;  conditional E-value: 0.014
       TPR_2   3 alynlGlayyklgdyeeAleafekAle 29 
                 a+  ++++y++l +y+ A+e  +k + 
  EEA19000.1 346 AHRVMAELYLNLEEYASAVEVARKGIT 372
                 78899***************9999875 PP

  == domain 4  score: 14.9 bits;  conditional E-value: 2.8e-05
       TPR_2   3 alynlGlayyklgdyeeAleafekAleldPnn 34 
                 +l  +Gl++++  dyeeA +++++A e dP n
  EEA19000.1 429 CLLGIGLILEEDHDYEEAYHFLQQARERDPSN 460
                 67789*************************87 PP

  == domain 5  score: -2.2 bits;  conditional E-value: 8.1
       TPR_2   1 aealynlGlayykl 14 
                 ae+ly++G + ++l
  EEA19000.1 503 AEILYRIGHCQWEL 516
                 799*****998766 PP

  == domain 6  score: 7.4 bits;  conditional E-value: 0.0066
       TPR_2   3 alynlGlayyklgdy.eeAleafekAleld 31 
                 a+ +lG  y+  ++  ++A+++f kA el 
  EEA19000.1 546 AYTRLGIYYADYKKDkARAKRCFHKAFELS 575
                 6677777777666666**********9995 PP

  == domain 7  score: 12.3 bits;  conditional E-value: 0.00019
       TPR_2   4 lynlGlayyklgdyeeAleafekAleldPnn 34 
                 + +lG + +++++y + +  +++Al++ P++
  EEA19000.1 626 YAALGVVQLNKQQYTKSIVSYQAALRISPGD 656
                 678**************************86 PP

  == domain 8  score: 12.2 bits;  conditional E-value: 0.00019
       TPR_2   4 lynlGlayyklgdyeeAleafekAleld 31 
                 +  lG++y ++g+y  A +afe A +l+
  EEA19000.1 660 WVGLGESYHNSGRYIAATKAFEHAEALE 687
                 889*********************8886 PP

  == domain 9  score: 12.5 bits;  conditional E-value: 0.00016
       TPR_2   5 ynlGlayyklgdyeeAleafekAleldPn 33 
                 y+l+++ ++lg+y++A+  +e +l++ Pn
  EEA19000.1 703 YMLANVKRELGEYDDAIGRYEDVLAIRPN 731
                 99**************************8 PP

  == domain 10  score: 0.1 bits;  conditional E-value: 1.5
       TPR_2  14 lgdyeeAleafekAleld 31 
                  g +++A++   +Ale++
  EEA19000.1 753 TGLFNDAAKSAHRALEIA 770
                 57799**********985 PP

  == domain 11  score: 0.5 bits;  conditional E-value: 1.1
       TPR_2   3 alynlGlayyk 13 
                  +ynlG+a y+
  EEA19000.1 877 SWYNLGWAEYR 887
                 6*******998 PP

  == domain 12  score: 6.1 bits;  conditional E-value: 0.017
       TPR_2  17 yeeAleafekAleld 31 
                 ++ A+++f++A+el+
  EEA19000.1 909 LKGAIRCFKQAIELE 923
                 389**********97 PP

  == domain 13  score: 6.6 bits;  conditional E-value: 0.012
       TPR_2   2 ealynlGlayyklgdyeeAleafekAleldPnn 34 
                 + + nlG  y+ ++d + A eaf +  + dP++
  EEA19000.1 961 QNWTNLGAFYLINNDIQLANEAFTRGQSADPDY 993
                 5699**********************9999985 PP

  == domain 14  score: 4.1 bits;  conditional E-value: 0.075
       TPR_2    2 ealynlGlayyklgdyeeAleafekAl 28  
                   a+  +G +++  gd+ eA+++f+   
  EEA19000.1  995 PAWLGQGIVALLFGDPSEARALFRHGF 1021
                  69999******************9765 PP

  == domain 15  score: 8.6 bits;  conditional E-value: 0.0027
       TPR_2    2 ealynlGlayyklgdyeeAleafekAleldPn 33  
                   a+  ++++++++ +y++A+e  e Al l  +
  EEA19000.1 1122 LANADIARVHLANHEYDQAVEKAELALTLSGD 1153
                  677889*********************99765 PP

  == domain 16  score: 9.7 bits;  conditional E-value: 0.0012
       TPR_2    3 alynlGlayyklgdyeeAleafekAleldPn 33  
                  a+   Glayy+l+  ++A++ f+ Al  ++n
  EEA19000.1 1171 AHLTAGLAYYYLKSMDQAIDMFRDALHEAEN 1201
                  68889*********************88777 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.3   0.4   0.00049      0.38       1      65 [.      13      78 ..      13      81 .. 0.92
   2 ?    5.4   0.0     0.033        26      14      47 ..     333     366 ..     331     370 .. 0.87
   3 ?    2.8   0.0      0.22   1.7e+02       6      30 ..     408     432 ..     406     439 .. 0.86
   4 !   26.0   0.2   1.3e-08   9.8e-06       3      67 ..     439     504 ..     435     505 .. 0.91
   5 ?   -1.5   0.2       4.8   3.7e+03       9      51 ..     563     605 ..     559     611 .. 0.77
   6 ?    6.9   0.0     0.012       9.1       5      47 ..     637     679 ..     633     689 .. 0.88
   7 ?    6.7   0.0     0.013        10      29      57 ..     703     731 ..     683     743 .. 0.66
   8 ?   -0.2   0.0       1.9   1.5e+03       9      29 ..     911     931 ..     909     936 .. 0.85
   9 !    9.6   0.0    0.0017       1.3       2      48 ..     971    1017 ..     970    1020 .. 0.92
  10 ?    2.7   0.1      0.23   1.8e+02      26      46 ..    1122    1142 ..    1112    1153 .. 0.89
  11 !   12.2   0.1   0.00025      0.19       7      39 ..    1185    1217 ..    1180    1221 .. 0.91
  12 ?   -1.4   0.0       4.5   3.5e+03      12      36 ..    1228    1252 ..    1223    1258 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00049
      TPR_19  1 llaegdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpdd.aryasLl 65
                +l+++d++ A++  + +++ d  n  a   L  a+ +lg +deAe    a+ + + +d  ++++L+
  EEA19000.1 13 ALDSKDFELAASKAKDLIDRDSTNYHAHVFLGLAQDKLGKPDEAESSYLAASRIKDKDkTAWQGLI 78
                68999*****************************************99999999999978888776 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.033
      TPR_19  14 leqalqedpknaearllLAeallalgqldeAeal 47 
                 +++ l+++ ++  a   +Ae++l+l +++ A ++
  EEA19000.1 333 MSNGLEQSSDSIIAHRVMAELYLNLEEYASAVEV 366
                 5667888999999999***************986 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.22
      TPR_19   6 dyaeAlalleqalqedpknaearll 30 
                 ++ eA  ++e++l+ +pkn   +l+
  EEA19000.1 408 NHPEAKGIFESILKRKPKNTKCLLG 432
                 6789***************987775 PP

  == domain 4  score: 26.0 bits;  conditional E-value: 1.3e-08
      TPR_19   3 aegdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpdd.aryasLlAk 67 
                 ++ dy+eA  +l+qa + dp n  +r  LA +   +g+l+   ++L+++++e  dd  + +  +A 
  EEA19000.1 439 EDHDYEEAYHFLQQARERDPSNVKIRSELAWCTALNGDLESGLEMLQDVLAEIEDDeNQSREFKAE 504
                 567****************************************************96776677665 PP

  == domain 5  score: -1.5 bits;  conditional E-value: 4.8
      TPR_19   9 eAlalleqalqedpknaearllLAeallalgqldeAealLdal 51 
                 +A + + +a++ +    ea+ +LA+a  +  ++d  ea+ +++
  EEA19000.1 563 RAKRCFHKAFELSSSEIEAAERLAKAFANKQEWDLVEAVAQRV 605
                 6777788888888888899999999988888888777766665 PP

  == domain 6  score: 6.9 bits;  conditional E-value: 0.012
      TPR_19   5 gdyaeAlalleqalqedpknaearllLAeallalgqldeAeal 47 
                 ++y+  +  +++al  +p++   + +L e + ++g++ +A ++
  EEA19000.1 637 QQYTKSIVSYQAALRISPGDYHSWVGLGESYHNSGRYIAATKA 679
                 788888999***************************9887665 PP

  == domain 7  score: 6.7 bits;  conditional E-value: 0.013
      TPR_19  29 llLAeallalgqldeAealLdalpeedpd 57 
                 + LA++  +lg++d+A+   +++++  p+
  EEA19000.1 703 YMLANVKRELGEYDDAIGRYEDVLAIRPN 731
                 55666666666666666666666555555 PP

  == domain 8  score: -0.2 bits;  conditional E-value: 1.9
      TPR_19   9 eAlalleqalqedpknaearl 29 
                  A++ ++qa++ +++n+e + 
  EEA19000.1 911 GAIRCFKQAIELEAGNSEFWN 931
                 79999************9886 PP

  == domain 9  score: 9.6 bits;  conditional E-value: 0.0017
      TPR_19    2 laegdyaeAlalleqalqedpknaearllLAeallalgqldeAealL 48  
                  l ++d + A +++++  ++dp++a a+l+  ++ l  g++ eA+al 
  EEA19000.1  971 LINNDIQLANEAFTRGQSADPDYAPAWLGQGIVALLFGDPSEARALF 1017
                  5678999999*****999**************************985 PP

  == domain 10  score: 2.7 bits;  conditional E-value: 0.23
      TPR_19   26 earllLAeallalgqldeAea 46  
                   a ++ A+++la+ ++d+A +
  EEA19000.1 1122 LANADIARVHLANHEYDQAVE 1142
                  567788*************76 PP

  == domain 11  score: 12.2 bits;  conditional E-value: 0.00025
      TPR_19    7 yaeAlalleqalqedpknaearllLAeallalg 39  
                   ++A+++++ al e+ +++e+  lLA++l+a g
  EEA19000.1 1185 MDQAIDMFRDALHEAENDPEVVCLLAQVLWAKG 1217
                  589***************************998 PP

  == domain 12  score: -1.4 bits;  conditional E-value: 4.5
      TPR_19   12 alleqalqedpknaearllL.Aeall 36  
                  +l+e++ +++p+++ a  lL A+all
  EEA19000.1 1228 QLFESV-EKNPEHLGAVTLLgAIALL 1252
                  677885.9999999999999777766 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   0.0     0.001      0.78       4      27 ..      40      63 ..      38      70 .. 0.85
   2 ?    3.8   0.0     0.073        57       4      30 ..     347     373 ..     344     376 .. 0.84
   3 !   15.3   0.0   1.7e-05     0.013       2      34 .]     428     460 ..     427     460 .. 0.95
   4 ?    0.3   0.0      0.91   7.1e+02       1      13 [.     503     515 ..     503     517 .. 0.85
   5 ?    2.3   0.7      0.21   1.6e+02       3      30 ..     546     574 ..     544     577 .. 0.72
   6 !   13.4   0.0   6.5e-05     0.051       4      33 ..     626     655 ..     624     656 .. 0.93
   7 !    7.8   0.0    0.0039       3.1       4      29 ..     660     685 ..     658     689 .. 0.89
   8 !    9.5   0.0    0.0011      0.87       5      33 ..     703     731 ..     700     732 .. 0.93
   9 ?   -1.1   0.0       2.5     2e+03      15      30 ..     754     769 ..     751     770 .. 0.87
  10 ?    1.2   0.3      0.49   3.8e+02       1      12 [.     875     886 ..     875     888 .. 0.81
  11 ?    6.0   0.0     0.014        11      19      31 ..     911     923 ..     909     926 .. 0.86
  12 ?    6.4   0.1     0.011       8.6       4      34 .]     963     993 ..     960     993 .. 0.93
  13 ?    0.5   0.0      0.79   6.1e+02       1      25 [.     994    1018 ..     994    1023 .. 0.89
  14 ?    1.8   0.1       0.3   2.3e+02       7      30 ..    1127    1150 ..    1121    1154 .. 0.82
  15 !   11.6   0.2   0.00024      0.19       8      33 ..    1176    1201 ..    1170    1202 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.001
                HHHHHHHHHHTT-HHHHHHHHHHH CS
       TPR_1  4 lynlGnayfklgkydeAleyyekA 27
                +  lG+a  klgk+deA+  y  A
  EEA19000.1 40 HVFLGLAQDKLGKPDEAESSYLAA 63
                5669**************999766 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.073
                 HHHHHHHHHHTT-HHHHHHHHHHHHHH CS
       TPR_1   4 lynlGnayfklgkydeAleyyekALel 30 
                 +  ++ +y++l++y  A+e  +k +++
  EEA19000.1 347 HRVMAELYLNLEEYASAVEVARKGITI 373
                 566899************988888776 PP

  == domain 3  score: 15.3 bits;  conditional E-value: 1.7e-05
                 HHHHHHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1   2 kalynlGnayfklgkydeAleyyekALelnPnn 34 
                 k+l ++G+++ +  +y+eA  + ++A e +P+n
  EEA19000.1 428 KCLLGIGLILEEDHDYEEAYHFLQQARERDPSN 460
                 57889**************************98 PP

  == domain 4  score: 0.3 bits;  conditional E-value: 0.91
                 HHHHHHHHHHHHH CS
       TPR_1   1 akalynlGnayfk 13 
                 a++ly++G++  +
  EEA19000.1 503 AEILYRIGHCQWE 515
                 799*******876 PP

  == domain 5  score: 2.3 bits;  conditional E-value: 0.21
                 HHHHHHHHHH.HTT-HHHHHHHHHHHHHH CS
       TPR_1   3 alynlGnayf.klgkydeAleyyekALel 30 
                 a+ +lG  y  ++++   A  ++ kA el
  EEA19000.1 546 AYTRLGIYYAdYKKDKARAKRCFHKAFEL 574
                 67777777751467788999999999988 PP

  == domain 6  score: 13.4 bits;  conditional E-value: 6.5e-05
                 HHHHHHHHHHTT-HHHHHHHHHHHHHHSTT CS
       TPR_1   4 lynlGnayfklgkydeAleyyekALelnPn 33 
                 +  lG++ +++++y + +  y+ AL++ P 
  EEA19000.1 626 YAALGVVQLNKQQYTKSIVSYQAALRISPG 655
                 6679***********************997 PP

  == domain 7  score: 7.8 bits;  conditional E-value: 0.0039
                 HHHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1   4 lynlGnayfklgkydeAleyyekALe 29 
                 + +lG  y++ g+y  A +++e A  
  EEA19000.1 660 WVGLGESYHNSGRYIAATKAFEHAEA 685
                 899******************98855 PP

  == domain 8  score: 9.5 bits;  conditional E-value: 0.0011
                 HHHHHHHHHTT-HHHHHHHHHHHHHHSTT CS
       TPR_1   5 ynlGnayfklgkydeAleyyekALelnPn 33 
                 y l+n+ ++lg+yd+A+  ye +L ++Pn
  EEA19000.1 703 YMLANVKRELGEYDDAIGRYEDVLAIRPN 731
                 889**************999999999998 PP

  == domain 9  score: -1.1 bits;  conditional E-value: 2.5
                 T-HHHHHHHHHHHHHH CS
       TPR_1  15 gkydeAleyyekALel 30 
                 g +++A +   +ALe+
  EEA19000.1 754 GLFNDAAKSAHRALEI 769
                 77999**********8 PP

  == domain 10  score: 1.2 bits;  conditional E-value: 0.49
                 HHHHHHHHHHHH CS
       TPR_1   1 akalynlGnayf 12 
                 a ++ynlG a +
  EEA19000.1 875 AVSWYNLGWAEY 886
                 678*****9865 PP

  == domain 11  score: 6.0 bits;  conditional E-value: 0.014
                 HHHHHHHHHHHHS CS
       TPR_1  19 eAleyyekALeln 31 
                  A+ ++++A+el+
  EEA19000.1 911 GAIRCFKQAIELE 923
                 59*********96 PP

  == domain 12  score: 6.4 bits;  conditional E-value: 0.011
                 HHHHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1   4 lynlGnayfklgkydeAleyyekALelnPnn 34 
                 + nlG+ y+ +++ + A e++ +  + +P++
  EEA19000.1 963 WTNLGAFYLINNDIQLANEAFTRGQSADPDY 993
                 9**********************99999986 PP

  == domain 13  score: 0.5 bits;  conditional E-value: 0.79
                  HHHHHHHHHHHHHTT-HHHHHHHHH CS
       TPR_1    1 akalynlGnayfklgkydeAleyye 25  
                  a a+ + G + +  g++ eA + ++
  EEA19000.1  994 APAWLGQGIVALLFGDPSEARALFR 1018
                  679*****************99886 PP

  == domain 14  score: 1.8 bits;  conditional E-value: 0.3
                  HHHHHHHTT-HHHHHHHHHHHHHH CS
       TPR_1    7 lGnayfklgkydeAleyyekALel 30  
                  ++ +++ + +yd+A+e  e AL+l
  EEA19000.1 1127 IARVHLANHEYDQAVEKAELALTL 1150
                  67789999*******988888887 PP

  == domain 15  score: 11.6 bits;  conditional E-value: 0.00024
                  HHHHHHTT-HHHHHHHHHHHHHHSTT CS
       TPR_1    8 GnayfklgkydeAleyyekALelnPn 33  
                  G+ay++l+  d+A++ ++ AL   +n
  EEA19000.1 1176 GLAYYYLKSMDQAIDMFRDALHEAEN 1201
                  9*******************987666 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.7   0.1   7.2e-05     0.056       2      33 ..      38      69 ..      37      70 .. 0.91
   2 !    8.7   0.0    0.0029       2.2       7      32 ..     350     375 ..     349     377 .. 0.90
   3 ?    5.3   0.0     0.034        27       4      34 .]     430     460 ..     427     460 .. 0.89
   4 ?   -0.2   0.0       2.1   1.6e+03       1      15 [.     503     517 ..     503     524 .. 0.85
   5 !    9.7   0.3    0.0014       1.1       1      32 [.     544     576 ..     544     578 .. 0.90
   6 !   11.2   0.0   0.00044      0.34       4      33 ..     626     655 ..     625     656 .. 0.94
   7 !   11.1   0.0   0.00047      0.37       2      30 ..     658     686 ..     657     689 .. 0.90
   8 ?    6.2   0.0     0.018        14       5      33 ..     703     731 ..     701     732 .. 0.91
   9 ?    2.1   0.0      0.37   2.9e+02      20      32 ..     912     924 ..     909     926 .. 0.86
  10 !    7.2   0.0    0.0088       6.8       1      33 [.     960     992 ..     960     993 .. 0.94
  11 ?   -1.0   0.0       3.6   2.8e+03       1      31 [.     994    1024 ..     994    1026 .. 0.83
  12 ?    0.3   0.1       1.4   1.1e+03       4      33 ..    1124    1153 ..    1121    1154 .. 0.85
  13 !    7.5   0.2    0.0067       5.2       3      28 ..    1171    1196 ..    1169    1202 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 7.2e-05
                CHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8  2 eayynlgsiylklgdyeeAkeyyekaleldpd 33
                +a++ lg++ +klg+ +eA+++y  a +++ +
  EEA19000.1 38 HAHVFLGLAQDKLGKPDEAESSYLAASRIKDK 69
                68899*********************999866 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.0029
                 HHHHHHHTT-HHHHHHHHHHHHHHHH CS
       TPR_8   7 lgsiylklgdyeeAkeyyekaleldp 32 
                 ++ +yl+l++y +A+e+ +k +++ +
  EEA19000.1 350 MAELYLNLEEYASAVEVARKGITIIK 375
                 589******************99866 PP

  == domain 3  score: 5.3 bits;  conditional E-value: 0.034
                 HHHHHHHHHHTT-HHHHHHHHHHHHHHHHH. CS
       TPR_8   4 yynlgsiylklgdyeeAkeyyekaleldpdn 34 
                 ++ +g+i+++  dyeeA  ++++a e dp+n
  EEA19000.1 430 LLGIGLILEEDHDYEEAYHFLQQARERDPSN 460
                 67799*******************9999975 PP

  == domain 4  score: -0.2 bits;  conditional E-value: 2.1
                 CCHHHHHHHHHHHTT CS
       TPR_8   1 aeayynlgsiylklg 15 
                 ae++y++g++ ++l 
  EEA19000.1 503 AEILYRIGHCQWELD 517
                 799*******99985 PP

  == domain 5  score: 9.7 bits;  conditional E-value: 0.0014
                 CCHHHHHHHHH.HHTT-HHHHHHHHHHHHHHHH CS
       TPR_8   1 aeayynlgsiy.lklgdyeeAkeyyekaleldp 32 
                 a+ay +lg  y + ++d+  Ak ++ ka el+ 
  EEA19000.1 544 APAYTRLGIYYaDYKKDKARAKRCFHKAFELSS 576
                 789*****6666******************985 PP

  == domain 6  score: 11.2 bits;  conditional E-value: 0.00044
                 HHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   4 yynlgsiylklgdyeeAkeyyekaleldpd 33 
                 y  lg + l++++y +++ +y+ al+++p 
  EEA19000.1 626 YAALGVVQLNKQQYTKSIVSYQAALRISPG 655
                 889*************************95 PP

  == domain 7  score: 11.1 bits;  conditional E-value: 0.00047
                 CHHHHHHHHHHHTT-HHHHHHHHHHHHHH CS
       TPR_8   2 eayynlgsiylklgdyeeAkeyyekalel 30 
                 ++++ lg  y++ g+y +A +++e+a  l
  EEA19000.1 658 HSWVGLGESYHNSGRYIAATKAFEHAEAL 686
                 79**********************99655 PP

  == domain 8  score: 6.2 bits;  conditional E-value: 0.018
                 HHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   5 ynlgsiylklgdyeeAkeyyekaleldpd 33 
                 y+l+++ ++lg+y+ A+  ye +l ++p+
  EEA19000.1 703 YMLANVKRELGEYDDAIGRYEDVLAIRPN 731
                 9****************999999999987 PP

  == domain 9  score: 2.1 bits;  conditional E-value: 0.37
                 HHHHHHHHHHHHH CS
       TPR_8  20 Akeyyekaleldp 32 
                 A+ ++++a+el+ 
  EEA19000.1 912 AIRCFKQAIELEA 924
                 99********986 PP

  == domain 10  score: 7.2 bits;  conditional E-value: 0.0088
                 CCHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   1 aeayynlgsiylklgdyeeAkeyyekaleldpd 33 
                 a+ + nlg  yl  +d++ A e++ +  ++dpd
  EEA19000.1 960 AQNWTNLGAFYLINNDIQLANEAFTRGQSADPD 992
                 678*****************************8 PP

  == domain 11  score: -1.0 bits;  conditional E-value: 3.6
                  CCHHHHHHHHHHHTT-HHHHHHHHHHHHHHH CS
       TPR_8    1 aeayynlgsiylklgdyeeAkeyyekaleld 31  
                  a+a++  g + l  gd  eA + +++  e++
  EEA19000.1  994 APAWLGQGIVALLFGDPSEARALFRHGFEIS 1024
                  577888888888889*********9988886 PP

  == domain 12  score: 0.3 bits;  conditional E-value: 1.4
                  HHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8    4 yynlgsiylklgdyeeAkeyyekaleldpd 33  
                     +++++l   +y++A+e  e al+l+ d
  EEA19000.1 1124 NADIARVHLANHEYDQAVEKAELALTLSGD 1153
                  567899999999*******99999999866 PP

  == domain 13  score: 7.5 bits;  conditional E-value: 0.0067
                  HHHHHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_8    3 ayynlgsiylklgdyeeAkeyyekal 28  
                  a++  g++y  l+ +++A+  ++ al
  EEA19000.1 1171 AHLTAGLAYYYLKSMDQAIDMFRDAL 1196
                  67889******************998 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.0     0.018        14       7      42 ..      43      78 ..      37      80 .. 0.87
   2 ?    5.6   0.0     0.046        36       3      28 ..     346     371 ..     345     376 .. 0.90
   3 ?   -0.9   0.0       5.3   4.1e+03      13      34 ..     405     426 ..     394     431 .. 0.77
   4 !    8.1   0.0    0.0071       5.5       5      42 ..     431     468 ..     427     470 .. 0.89
   5 ?    1.4   0.0         1   7.8e+02      14      34 ..     474     494 ..     470     504 .. 0.84
   6 ?    2.3   0.2      0.53   4.1e+02       3      43 ..     546     587 ..     544     589 .. 0.83
   7 ?    7.5   0.0     0.011       8.3       4      42 ..     626     664 ..     623     666 .. 0.89
   8 ?    1.9   0.0       0.7   5.4e+02       4      30 ..     660     686 ..     657     689 .. 0.88
   9 !   17.8   0.0   5.4e-06    0.0042       5      43 ..     703     741 ..     699     742 .. 0.92
  10 ?    4.0   0.0      0.14   1.1e+02      17      41 ..     909     933 ..     904     936 .. 0.87
  11 ?    5.2   0.0      0.06        47       6      39 ..     965     998 ..     960    1003 .. 0.91
  12 ?    5.0   0.0     0.069        54       3      31 ..     996    1024 ..     994    1033 .. 0.84
  13 ?    6.5   0.2     0.022        17       4      34 ..    1124    1154 ..    1121    1158 .. 0.88
  14 !   14.7   0.2   5.2e-05     0.041       3      43 ..    1171    1211 ..    1169    1213 .. 0.94
  15 ?    3.5   0.0      0.21   1.7e+02       7      43 ..    1209    1248 ..    1208    1249 .. 0.82

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.018
      TPR_14  7 laeallalGdpdeAiallrralalaPddaeawllla 42
                l+ a   lG+pdeA+  + +a +   +d +aw  l 
  EEA19000.1 43 LGLAQDKLGKPDEAESSYLAASRIKDKDKTAWQGLI 78
                77788899************************9886 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.046
      TPR_14   3 allalaeallalGdpdeAiallrral 28 
                 a++ +ae++l+l++++ A++++r+ +
  EEA19000.1 346 AHRVMAELYLNLEEYASAVEVARKGI 371
                 67789*****************9976 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 5.3
      TPR_14  13 alGdpdeAiallrralalaPdd 34 
                   +++ eA  +++ +l++ P++
  EEA19000.1 405 SPRNHPEAKGIFESILKRKPKN 426
                 4468999***********9998 PP

  == domain 4  score: 8.1 bits;  conditional E-value: 0.0071
      TPR_14   5 lalaeallalGdpdeAiallrralalaPddaeawllla 42 
                 l ++ +l++  d++eA   l++a +++P++  ++ +la
  EEA19000.1 431 LGIGLILEEDHDYEEAYHFLQQARERDPSNVKIRSELA 468
                 567789999**********************9998887 PP

  == domain 5  score: 1.4 bits;  conditional E-value: 1
      TPR_14  14 lGdpdeAiallrralalaPdd 34 
                 +Gd++  +++l+++la   dd
  EEA19000.1 474 NGDLESGLEMLQDVLAEIEDD 494
                 79*************965555 PP

  == domain 6  score: 2.3 bits;  conditional E-value: 0.53
      TPR_14   3 allalaeallal.GdpdeAiallrralalaPddaeawlllaq 43 
                 a+ +l+ +++    d ++A +++++a +l  ++ ea  +la+
  EEA19000.1 546 AYTRLGIYYADYkKDKARAKRCFHKAFELSSSEIEAAERLAK 587
                 566788888875156789**********************97 PP

  == domain 7  score: 7.5 bits;  conditional E-value: 0.011
      TPR_14   4 llalaeallalGdpdeAiallrralalaPddaeawllla 42 
                 ++al+ + l+ +++ ++i  +++al+  P+d   w  l+
  EEA19000.1 626 YAALGVVQLNKQQYTKSIVSYQAALRISPGDYHSWVGLG 664
                 799**************************9987777776 PP

  == domain 8  score: 1.9 bits;  conditional E-value: 0.7
      TPR_14   4 llalaeallalGdpdeAiallrralal 30 
                 +  l+e + ++G++ +A ++++ a al
  EEA19000.1 660 WVGLGESYHNSGRYIAATKAFEHAEAL 686
                 77899****************998765 PP

  == domain 9  score: 17.8 bits;  conditional E-value: 5.4e-06
      TPR_14   5 lalaeallalGdpdeAiallrralalaPddaeawlllaq 43 
                 ++la + ++lG++d+Ai  ++++la  P++  + ++l q
  EEA19000.1 703 YMLANVKRELGEYDDAIGRYEDVLAIRPNEFGVMIALLQ 741
                 89***************************9999888876 PP

  == domain 10  score: 4.0 bits;  conditional E-value: 0.14
      TPR_14  17 pdeAiallrralalaPddaeawlll 41 
                 +++Ai+++++a++l  ++ e+w  l
  EEA19000.1 909 LKGAIRCFKQAIELEAGNSEFWNSL 933
                 689****************999665 PP

  == domain 11  score: 5.2 bits;  conditional E-value: 0.06
      TPR_14   6 alaeallalGdpdeAiallrralalaPddaeawl 39 
                  l++++l + d + A +++ r  +++Pd a awl
  EEA19000.1 965 NLGAFYLINNDIQLANEAFTRGQSADPDYAPAWL 998
                 5899*****************************8 PP

  == domain 12  score: 5.0 bits;  conditional E-value: 0.069
      TPR_14    3 allalaeallalGdpdeAiallrralala 31  
                  a+l  + + l  Gdp eA+al+r   +  
  EEA19000.1  996 AWLGQGIVALLFGDPSEARALFRHGFEIS 1024
                  89999*****************9876665 PP

  == domain 13  score: 6.5 bits;  conditional E-value: 0.022
      TPR_14    4 llalaeallalGdpdeAiallrralalaPdd 34  
                   +++a+++la+ ++d+A++ ++ al l  dd
  EEA19000.1 1124 NADIARVHLANHEYDQAVEKAELALTLSGDD 1154
                  5799******************999998887 PP

  == domain 14  score: 14.7 bits;  conditional E-value: 5.2e-05
      TPR_14    3 allalaeallalGdpdeAiallrralalaPddaeawlllaq 43  
                  a+l ++ a++ l   d+Ai+++r+al  a +d+e+  llaq
  EEA19000.1 1171 AHLTAGLAYYYLKSMDQAIDMFRDALHEAENDPEVVCLLAQ 1211
                  78899999********************************9 PP

  == domain 15  score: 3.5 bits;  conditional E-value: 0.21
      TPR_14    7 laeallalG.dpde..AiallrralalaPddaeawlllaq 43  
                  la++l+a G + ++  A++ l + ++++P+++ a +ll+ 
  EEA19000.1 1209 LAQVLWAKGgEEERnvAREQLFESVEKNPEHLGAVTLLGA 1248
                  8999998653555577999999999**********99986 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.2   5.4e-08   4.2e-05       2      60 ..       8      63 ..       7      70 .. 0.89
   2 ?   -1.9   0.1         7   5.4e+03      33      63 ..      92     120 ..      84     123 .. 0.76
   3 ?   -0.8   0.1       3.3   2.6e+03       4      21 ..     351     368 ..     345     371 .. 0.67
   4 ?    2.9   0.0      0.22   1.8e+02      12      53 ..     408     446 ..     407     447 .. 0.93
   5 !   12.6   0.0   0.00021      0.17       3      59 ..     433     486 ..     431     495 .. 0.87
   6 ?    0.3   0.8       1.5   1.2e+03       9      61 ..     557     606 ..     552     615 .. 0.75
   7 !   13.2   0.1   0.00013       0.1       3      54 ..     629     677 ..     627     686 .. 0.86
   8 !   10.0   0.0    0.0014       1.1       1      27 [.     703     729 ..     703     739 .. 0.92
   9 ?    5.6   0.1     0.033        26      15      47 ..     762     794 ..     758     820 .. 0.86
  10 ?   -2.2   0.3       8.6   6.7e+03      36      46 ..     877     887 ..     859     888 .. 0.67
  11 ?    1.0   0.0      0.87   6.8e+02      15      43 ..     911     936 ..     904     941 .. 0.87
  12 !   20.8   0.6   5.7e-07   0.00044      10      58 ..     973    1018 ..     945    1019 .. 0.95
  13 ?    2.1   0.1       0.4   3.1e+02       2      27 ..    1126    1151 ..    1125    1157 .. 0.80
  14 !   10.1   0.1    0.0013         1       1      48 [.    1173    1217 ..    1173    1221 .. 0.83
  15 ?   -1.2   0.0       4.2   3.3e+03      22      49 ..    1228    1255 ..    1222    1258 .. 0.74

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 5.4e-08
      TPR_16  2 alaraalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraa 60
                ++ ++al+++d++ Aa  ++ +++rd   + +++A+ +lg+a  ++g  +eA+  y+aa
  EEA19000.1  8 KAVKSALDSKDFELAASKAKDLIDRD---STNYHAHVFLGLAQDKLGKPDEAESSYLAA 63
                67899*********************...99999*******************555554 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 7
      TPR_16  33 aaeAllllgdaalrqgrlaeAaalyraalra 63 
                  ++ +l lg++++++ + ++ +  y+   ++
  EEA19000.1  92 YHDVALRLGQILAENDERDRSLYIYNY--QH 120
                 56788999**99999888888755555..55 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 3.3
      TPR_16   4 araalragdyddAaaale 21 
                 a ++l++ +y+ A+++++
  EEA19000.1 351 AELYLNLEEYASAVEVAR 368
                 566777777777776654 PP

  == domain 4  score: 2.9 bits;  conditional E-value: 0.22
      TPR_16  12 dyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeA 53 
                 + ++A   +e  lkr    P +   ll+ g+++ +  +++eA
  EEA19000.1 408 NHPEAKGIFESILKRK---PKNTKCLLGIGLILEEDHDYEEA 446
                 67789999********...*****************9**998 PP

  == domain 5  score: 12.6 bits;  conditional E-value: 0.00021
      TPR_16   3 laraalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyra 59 
                  ++++ +  dy++A + l++a++rd   P ++  + +l+++ + +g+l+  ++ ++ 
  EEA19000.1 433 IGLILEEDHDYEEAYHFLQQARERD---PSNVKIRSELAWCTALNGDLESGLEMLQD 486
                 578889999****************...********************988866655 PP

  == domain 6  score: 0.3 bits;  conditional E-value: 1.5
      TPR_16   9 ragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraal 61 
                 + +d ++A + ++ a ++    +   eA+  l+ a++ ++++++ +a+ ++ +
  EEA19000.1 557 YKKDKARAKRCFHKAFELS---SSEIEAAERLAKAFANKQEWDLVEAVAQRVV 606
                 5667788999999999999...7778899999999999888887666665555 PP

  == domain 7  score: 13.2 bits;  conditional E-value: 0.00013
      TPR_16   3 laraalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAa 54 
                 l+   l+ ++y++ +  ++aal+     P +++++ +lg+++   gr+ +A 
  EEA19000.1 629 LGVVQLNKQQYTKSIVSYQAALRIS---PGDYHSWVGLGESYHNSGRYIAAT 677
                 6667788999999999*********...*******************97776 PP

  == domain 8  score: 10.0 bits;  conditional E-value: 0.0014
      TPR_16   1 lalaraalragdyddAaaaleaalkrd 27 
                 ++la+  +++g+yddA+ ++e +l+ +
  EEA19000.1 703 YMLANVKRELGEYDDAIGRYEDVLAIR 729
                 89**********************977 PP

  == domain 9  score: 5.6 bits;  conditional E-value: 0.033
      TPR_16  15 dAaaaleaalkrdpssPdaaeAllllgdaalrq 47 
                  A +ale+a+++++++P     + + gda++++
  EEA19000.1 762 SAHRALEIAIAMAKETPNVFNLWKAAGDACAVF 794
                 599**************************9987 PP

  == domain 10  score: -2.2 bits;  conditional E-value: 8.6
      TPR_16  36 Allllgdaalr 46 
                 ++++lg+a +r
  EEA19000.1 877 SWYNLGWAEYR 887
                 57777777776 PP

  == domain 11  score: 1.0 bits;  conditional E-value: 0.87
      TPR_16  15 dAaaaleaalkrdpssPdaaeAllllgda 43 
                  A++ +++a+++      + e+++ lg++
  EEA19000.1 911 GAIRCFKQAIELE---AGNSEFWNSLGVV 936
                 699**********...88888*****987 PP

  == domain 12  score: 20.8 bits;  conditional E-value: 5.7e-07
      TPR_16   10 agdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyr 58  
                  ++d + A +a+++   +d   Pd a A+l+ g +al +g+  eA+al+r
  EEA19000.1  973 NNDIQLANEAFTRGQSAD---PDYAPAWLGQGIVALLFGDPSEARALFR 1018
                  689999**9**9999999...**************************97 PP

  == domain 13  score: 2.1 bits;  conditional E-value: 0.4
      TPR_16    2 alaraalragdyddAaaaleaalkrd 27  
                  + ar +l++ +yd+A++ +e al + 
  EEA19000.1 1126 DIARVHLANHEYDQAVEKAELALTLS 1151
                  57999**********99998776655 PP

  == domain 14  score: 10.1 bits;  conditional E-value: 0.0013
      TPR_16    1 lalaraalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqg 48  
                  l +++a+++++  d+A+ +++ al  +  +P+      ll+++++++g
  EEA19000.1 1173 LTAGLAYYYLKSMDQAIDMFRDALHEAENDPE---VVCLLAQVLWAKG 1217
                  5789***********************77776...7777777766654 PP

  == domain 15  score: -1.2 bits;  conditional E-value: 4.2
      TPR_16   22 aalkrdpssPdaaeAllllgdaalrqgr 49  
                  ++ ++  + P++  A  llg +al  g+
  EEA19000.1 1228 QLFESVEKNPEHLGAVTLLGAIALLDGD 1255
                  44444455599999*********99988 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.0      0.13     1e+02       4      33 ..      28      57 ..      26      58 .. 0.92
   2 ?    3.4   0.0      0.16   1.3e+02       5      33 ..     336     364 ..     332     365 .. 0.89
   3 ?    3.0   0.0      0.21   1.6e+02       2      32 ..     416     446 ..     415     447 .. 0.91
   4 !    7.3   0.0    0.0088       6.9       7      30 ..     455     478 ..     449     482 .. 0.88
   5 ?    4.8   0.3     0.053        42       2      32 ..     533     564 ..     532     566 .. 0.80
   6 ?    0.8   0.0         1   7.9e+02      12      31 ..     622     641 ..     618     643 .. 0.87
   7 !   12.4   0.0    0.0002      0.16       2      32 ..     646     676 ..     645     678 .. 0.95
   8 ?    0.2   0.0       1.7   1.3e+03      17      33 ..     703     719 ..     695     720 .. 0.90
   9 ?    4.9   0.1     0.052        41       2      24 ..     860     886 ..     859     901 .. 0.77
  10 !    9.6   0.0    0.0016       1.3       1      22 [.     915     936 ..     915     940 .. 0.93
  11 !    8.1   0.2     0.005       3.9       4      32 ..     951     979 ..     948     981 .. 0.87
  12 ?    5.8   0.0     0.026        21       2      33 ..     983    1014 ..     982    1015 .. 0.89
  13 ?   -1.7   0.1       6.5   5.1e+03      17      34 .]    1125    1142 ..    1120    1142 .. 0.81
  14 ?   -1.2   0.0       4.7   3.7e+03       5      23 ..    1195    1213 ..    1191    1221 .. 0.75
  15 ?   -1.0   0.0       3.9     3e+03       5      30 ..    1232    1257 ..    1231    1261 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.13
      TPR_17  4 kaleldPnnadaynnLAelllknGdlmtAr 33
                  +++d +n  a+  L+ ++ k+G++++A+
  EEA19000.1 28 DLIDRDSTNYHAHVFLGLAQDKLGKPDEAE 57
                6799************************98 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.16
      TPR_17   5 aleldPnnadaynnLAelllknGdlmtAr 33 
                  le+  ++  a+  +Ael+l++ +++ A+
  EEA19000.1 336 GLEQSSDSIIAHRVMAELYLNLEEYASAV 364
                 6899999999**************99886 PP

  == domain 3  score: 3.0 bits;  conditional E-value: 0.21
      TPR_17   2 ylkaleldPnnadaynnLAelllknGdlmtA 32 
                 ++  l++ P+n + +   + +l++ +d+++A
  EEA19000.1 416 FESILKRKPKNTKCLLGIGLILEEDHDYEEA 446
                 5667999*********************998 PP

  == domain 4  score: 7.3 bits;  conditional E-value: 0.0088
      TPR_17   7 eldPnnadaynnLAelllknGdlm 30 
                 e+dP+n++   +LA++ + nGdl+
  EEA19000.1 455 ERDPSNVKIRSELAWCTALNGDLE 478
                 99*******************986 PP

  == domain 5  score: 4.8 bits;  conditional E-value: 0.053
      TPR_17   2 ylkaleldPnnadaynnLAelll.knGdlmtA 32 
                 +l +++ d n+a+ay+ L+ +++  ++d+++A
  EEA19000.1 533 FLASIQADLNYAPAYTRLGIYYAdYKKDKARA 564
                 678899999*************9555566666 PP

  == domain 6  score: 0.8 bits;  conditional E-value: 1
      TPR_17  12 nadaynnLAelllknGdlmt 31 
                 ++++y  L++++l++ ++ +
  EEA19000.1 622 HSWPYAALGVVQLNKQQYTK 641
                 799************99865 PP

  == domain 7  score: 12.4 bits;  conditional E-value: 0.0002
      TPR_17   2 ylkaleldPnnadaynnLAelllknGdlmtA 32 
                 y+ al++ P +  ++  L+e +++ G++  A
  EEA19000.1 646 YQAALRISPGDYHSWVGLGESYHNSGRYIAA 676
                 9**************************9776 PP

  == domain 8  score: 0.2 bits;  conditional E-value: 1.7
      TPR_17  17 nnLAelllknGdlmtAr 33 
                 ++LA++ +++G++++A+
  EEA19000.1 703 YMLANVKRELGEYDDAI 719
                 89*************96 PP

  == domain 9  score: 4.9 bits;  conditional E-value: 0.052
      TPR_17   2 ylkaleldPnn....adaynnLAelll 24 
                 y++a+    n+    a++++nL+++ +
  EEA19000.1 860 YKRAVYVSANDrhaqAVSWYNLGWAEY 886
                 6666666667777779********977 PP

  == domain 10  score: 9.6 bits;  conditional E-value: 0.0016
      TPR_17   1 lylkaleldPnnadaynnLAel 22 
                 ++++a+el+  n++++n L+++
  EEA19000.1 915 CFKQAIELEAGNSEFWNSLGVV 936
                 79*****************975 PP

  == domain 11  score: 8.1 bits;  conditional E-value: 0.005
      TPR_17   4 kaleldPnnadaynnLAelllknGdlmtA 32 
                 ++l l+  +a  ++nL+ ++l n+d + A
  EEA19000.1 951 RSLHLNDRSAQNWTNLGAFYLINNDIQLA 979
                 677788899***************98866 PP

  == domain 12  score: 5.8 bits;  conditional E-value: 0.026
      TPR_17    2 ylkaleldPnnadaynnLAelllknGdlmtAr 33  
                  +++    dP++a+a+   + + l  Gd+ +Ar
  EEA19000.1  983 FTRGQSADPDYAPAWLGQGIVALLFGDPSEAR 1014
                  5667788*********************9998 PP

  == domain 13  score: -1.7 bits;  conditional E-value: 6.5
      TPR_17   17 nnLAelllknGdlmtArq 34  
                     A+++l n+++++A++
  EEA19000.1 1125 ADIARVHLANHEYDQAVE 1142
                  5679999********975 PP

  == domain 14  score: -1.2 bits;  conditional E-value: 4.7
      TPR_17    5 aleldPnnadaynnLAell 23  
                  al    n++++ ++LA++l
  EEA19000.1 1195 ALHEAENDPEVVCLLAQVL 1213
                  55556799********986 PP

  == domain 15  score: -1.0 bits;  conditional E-value: 3.9
      TPR_17    5 aleldPnnadaynnLAelllknGdlm 30  
                  ++e++P +  a ++L+ + l  Gd +
  EEA19000.1 1232 SVEKNPEHLGAVTLLGAIALLDGDED 1257
                  7899****9999****9999999866 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.031        24      50      75 ..      42      67 ..      28      69 .. 0.86
   2 ?    2.0   0.0      0.32   2.5e+02      44      74 ..     343     373 ..     334     376 .. 0.76
   3 !    7.7   0.1    0.0054       4.2      46      74 ..     428     456 ..     403     459 .. 0.72
   4 !    8.4   0.7    0.0033       2.5       5      72 ..     430     488 ..     426     493 .. 0.73
   5 ?    4.9   0.1      0.04        31       9      65 ..     467     522 ..     461     526 .. 0.88
   6 ?    3.0   0.3      0.16   1.2e+02       3      74 ..     503     574 ..     501     577 .. 0.81
   7 !   13.1   0.2   0.00011     0.087       8      73 ..     628     685 ..     622     686 .. 0.92
   8 !   25.0   0.2   2.2e-08   1.7e-05       5      76 ..     659     730 ..     657     731 .. 0.95
   9 !   14.2   0.1   5.2e-05      0.04       8      75 ..     704     770 ..     697     772 .. 0.74
  10 ?   -1.1   0.0         3   2.3e+03      16      54 ..     753     790 ..     750     792 .. 0.69
  11 ?    1.5   0.2      0.47   3.7e+02      38      57 ..     868     887 ..     854     891 .. 0.69
  12 !    9.7   0.0    0.0013         1       6      75 ..     963    1024 ..     958    1026 .. 0.78
  13 ?   -2.1   0.1       6.5     5e+03      51      66 ..    1079    1095 ..    1072    1098 .. 0.52
  14 ?    3.9   0.2     0.085        66       8      32 ..    1126    1150 ..    1119    1158 .. 0.70
  15 ?    5.8   0.4     0.022        17      45      72 ..    1169    1196 ..    1165    1199 .. 0.81
  16 ?   -1.2   0.0       3.2   2.5e+03      33      54 ..    1233    1252 ..    1227    1272 .. 0.68

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.031
      TPR_12 50 nLgrlyralgryeeAlelleealaia 75
                 Lg ++++lg+++eA++ +  a +i+
  EEA19000.1 42 FLGLAQDKLGKPDEAESSYLAASRIK 67
                589999999******99998888876 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.32
      TPR_12  44 tattlrnLgrlyralgryeeAlelleealai 74 
                  +++ r +++ly+ l++y+ A+e  ++ + i
  EEA19000.1 343 SIIAHRVMAELYLNLEEYASAVEVARKGITI 373
                 5677888888888888888888888877766 PP

  == domain 3  score: 7.7 bits;  conditional E-value: 0.0054
      TPR_12  46 ttlrnLgrlyralgryeeAlelleealai 74 
                  +l ++g ++++  +yeeA  +l++a ++
  EEA19000.1 428 KCLLGIGLILEEDHDYEEAYHFLQQARER 456
                 56777777777777777777777777776 PP

  == domain 4  score: 8.4 bits;  conditional E-value: 0.0033
      TPR_12   5 alnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleeal 72 
                 +l  ++++l +  +y+eA  +l++a+e+      p     + ++  L+++  + g++e  le+l+++l
  EEA19000.1 430 LL-GIGLILEEDHDYEEAYHFLQQARERD-----PS---NVKIRSELAWCTALNGDLESGLEMLQDVL 488
                 44.78888888999999999999996666.....54...36677777777777777777777777766 PP

  == domain 5  score: 4.9 bits;  conditional E-value: 0.04
      TPR_12   9 laavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAl 65 
                 la + +  g+++  le+l+ +l+ ++   +  ++  a++l+ +g ++++l ++  A 
  EEA19000.1 467 LAWCTALNGDLESGLEMLQDVLAEIEDDENQSREFKAEILYRIGHCQWEL-DPSSAA 522
                 66677889*****************************************9.777665 PP

  == domain 6  score: 3.0 bits;  conditional E-value: 0.16
      TPR_12   3 atalnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrly.ralgryeeAlelleealai 74 
                 a +l++++++ ++l     A+++ + a++ + ++     +++a ++  Lg++y ++ ++ + A + + +a ++
  EEA19000.1 503 AEILYRIGHCQWELDPSSAARKNRNGAYASFLASIQA-DLNYAPAYTRLGIYYaDYKKDKARAKRCFHKAFEL 574
                 6778889999999999999999999999999666544.469***********955889999999988888776 PP

  == domain 7  score: 13.1 bits;  conditional E-value: 0.00011
      TPR_12   8 nlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleeala 73 
                  l++v +  ++y++++  +++al+i    +G++h     +  +Lg+ y+ +gry +A +++e+a a
  EEA19000.1 628 ALGVVQLNKQQYTKSIVSYQAALRIS---PGDYH-----SWVGLGESYHNSGRYIAATKAFEHAEA 685
                 5999999*******************...*****.....889********************9977 PP

  == domain 8  score: 25.0 bits;  conditional E-value: 2.2e-08
      TPR_12   5 alnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                 +++ l++ ++  gry  A + +e+a ++ + l   ++ +   + + L+ + r+lg+y++A+ ++e++lai++
  EEA19000.1 659 SWVGLGESYHNSGRYIAATKAFEHAEALESTLSKSESSNIWFSKYMLANVKRELGEYDDAIGRYEDVLAIRP 730
                 5789*************************999999***********************************86 PP

  == domain 9  score: 14.2 bits;  conditional E-value: 5.2e-05
      TPR_12   8 nlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaia 75 
                  la+v r+lg+yd+A+  +e +l+i+ + +G    ++++tl   ++  + +g + +A +   +al+ia
  EEA19000.1 704 MLANVKRELGEYDDAIGRYEDVLAIRPNEFG-VMIALLQTLTESSWKNLDTGLFNDAAKSAHRALEIA 770
                 4899999999999999999999999854554.357777777777777777777777777777777765 PP

  == domain 10  score: -1.1 bits;  conditional E-value: 3
      TPR_12  16 lgrydeAlellekaleiarrllGpdhpltattlrnLgrl 54 
                  g + +A +  ++aleia +   ++ p++ +   + g++
  EEA19000.1 753 TGLFNDAAKSAHRALEIAIAM-AKETPNVFNLWKAAGDA 790
                 567788999999999999442.36666666666666665 PP

  == domain 11  score: 1.5 bits;  conditional E-value: 0.47
      TPR_12  38 GpdhpltattlrnLgrlyra 57 
                   d+++ a + +nLg++ ++
  EEA19000.1 868 ANDRHAQAVSWYNLGWAEYR 887
                 35666999999999999665 PP

  == domain 12  score: 9.7 bits;  conditional E-value: 0.0013
      TPR_12    6 lnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaia 75  
                  ++nl+a+++   +    ++l ++a  + +++     p++a +  + g++ +++g++ eA++l+++  +i 
  EEA19000.1  963 WTNLGAFYLINND----IQLANEAFTRGQSA----DPDYAPAWLGQGIVALLFGDPSEARALFRHGFEIS 1024
                  5577777777777....66666676666655....566899***********************999886 PP

  == domain 13  score: -2.1 bits;  conditional E-value: 6.5
      TPR_12   51 Lgrly.ralgryeeAle 66  
                  L+ l+ ++ g+y++A++
  EEA19000.1 1079 LSALFaERIGEYAQAES 1095
                  44454234466666655 PP

  == domain 14  score: 3.9 bits;  conditional E-value: 0.085
      TPR_12    8 nlaavlrrlgrydeAlellekalei 32  
                   +a v+++  +yd+A e  e al +
  EEA19000.1 1126 DIARVHLANHEYDQAVEKAELALTL 1150
                  3777777777777777777777765 PP

  == domain 15  score: 5.8 bits;  conditional E-value: 0.022
      TPR_12   45 attlrnLgrlyralgryeeAlelleeal 72  
                  +++  + g +y++l+  ++A++++++al
  EEA19000.1 1169 LSAHLTAGLAYYYLKSMDQAIDMFRDAL 1196
                  5677788888888889999999988887 PP

  == domain 16  score: -1.2 bits;  conditional E-value: 3.2
      TPR_12   33 arrllGpdhpltattlrnLgrl 54  
                  ++   +p+h++++t l +++ l
  EEA19000.1 1233 VE--KNPEHLGAVTLLGAIALL 1252
                  44..459999999999999887 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   0.0     0.011       8.9       1      28 [.      39      64 ..      39      72 .. 0.82
   2 ?   -1.3   0.0       3.8     3e+03      15      25 ..      74      84 ..      73      94 .. 0.86
   3 ?    3.5   0.0      0.11        87       5      28 ..     350     371 ..     346     381 .. 0.83
   4 !    7.4   0.1    0.0062       4.9       1      35 [.     429     461 ..     429     462 .. 0.93
   5 ?    5.3   0.0     0.029        23       2      33 ..     626     655 ..     626     658 .. 0.85
   6 ?    2.0   0.0      0.34   2.7e+02       2      27 ..     660     687 ..     659     696 .. 0.76
   7 !   16.5   0.0   7.8e-06    0.0061       4      34 ..     704     734 ..     703     736 .. 0.90
   8 ?    1.4   0.0      0.52   4.1e+02      17      29 ..     911     923 ..     909     929 .. 0.73
   9 ?   -2.1   0.1         7   5.5e+03      10      20 ..    1085    1095 ..    1080    1097 .. 0.82
  10 ?    2.7   0.1      0.21   1.6e+02       5      29 ..    1127    1151 ..    1125    1156 .. 0.80
  11 ?    2.9   0.0      0.17   1.3e+02      15      35 ..    1185    1203 ..    1172    1206 .. 0.78

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.011
       TPR_7  1 aLlnLarlysrlGdyeeAielyeqsLal 28
                a++ L+ ++ +lG+ +eA++ y +  a 
  EEA19000.1 39 AHVFLGLAQDKLGKPDEAESSYLA--AS 64
                5678******************99..54 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 3.8
       TPR_7 15 yeeAielyeqs 25
                ++ +i+lye++
  EEA19000.1 74 WQGLITLYEKQ 84
                8899*****93 PP

  == domain 3  score: 3.5 bits;  conditional E-value: 0.11
       TPR_7   5 LarlysrlGdyeeAielyeqsLal 28 
                 +a+ly +l +y+ A+e+ ++  ++
  EEA19000.1 350 MAELYLNLEEYASAVEVARK--GI 371
                 89*************99777..55 PP

  == domain 4  score: 7.4 bits;  conditional E-value: 0.0062
       TPR_7   1 aLlnLarlysrlGdyeeAielyeqsLaltkdpeda 35 
                 +Ll ++ + +++ dyeeA  +++q  a ++dp+++
  EEA19000.1 429 CLLGIGLILEEDHDYEEAYHFLQQ--ARERDPSNV 461
                 78999*******************..*****9986 PP

  == domain 5  score: 5.3 bits;  conditional E-value: 0.029
       TPR_7   2 LlnLarlysrlGdyeeAielyeqsLaltkdpe 33 
                 + +L++++ + ++y + i  y++  al+ +p+
  EEA19000.1 626 YAALGVVQLNKQQYTKSIVSYQA--ALRISPG 655
                 679********************..6665554 PP

  == domain 6  score: 2.0 bits;  conditional E-value: 0.34
       TPR_7   2 LlnLarlysrlGdyeeAielyeq..sLa 27 
                 ++ L++ y++ G+y  A + +e   +L+
  EEA19000.1 660 WVGLGESYHNSGRYIAATKAFEHaeALE 687
                 6789**********99999999944444 PP

  == domain 7  score: 16.5 bits;  conditional E-value: 7.8e-06
       TPR_7   4 nLarlysrlGdyeeAielyeqsLaltkdped 34 
                  La++ ++lG+y++Ai+ ye +La++  +++
  EEA19000.1 704 MLANVKRELGEYDDAIGRYEDVLAIRPNEFG 734
                 59999*******************9988776 PP

  == domain 8  score: 1.4 bits;  conditional E-value: 0.52
       TPR_7  17 eAielyeqsLalt 29 
                  Ai++++q+++l+
  EEA19000.1 911 GAIRCFKQAIELE 923
                 69******55554 PP

  == domain 9  score: -2.1 bits;  conditional E-value: 7
       TPR_7   10 srlGdyeeAie 20  
                  +r G+y++A++
  EEA19000.1 1085 ERIGEYAQAES 1095
                  689******86 PP

  == domain 10  score: 2.7 bits;  conditional E-value: 0.21
       TPR_7    5 LarlysrlGdyeeAielyeqsLalt 29  
                  +ar++ +  +y++A+e  e +L l 
  EEA19000.1 1127 IARVHLANHEYDQAVEKAELALTLS 1151
                  789999999********99955554 PP

  == domain 11  score: 2.9 bits;  conditional E-value: 0.17
       TPR_7   15 yeeAielyeqsLaltkdpeda 35  
                  +++Ai+ ++   al+++++d+
  EEA19000.1 1185 MDQAIDMFRD--ALHEAENDP 1203
                  69********..666666655 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.1       1.2   9.7e+02       7      42 .]      50      85 ..      44      85 .. 0.85
   2 ?    2.6   0.1      0.14   1.1e+02       9      35 ..     442     468 ..     436     468 .. 0.92
   3 ?   -2.1   1.8       4.1   3.2e+03      12      39 ..     528     554 ..     522     556 .. 0.82
   4 !   17.7   0.0   2.7e-06    0.0021       7      42 .]     636     671 ..     632     671 .. 0.95
   5 !   12.6   0.0   0.00011     0.084       2      26 ..     707     731 ..     706     735 .. 0.93
   6 ?   -2.5   0.1       5.5   4.3e+03      14      26 ..     857     869 ..     855     884 .. 0.60
   7 !   12.6   0.0   0.00011     0.085      10      37 ..     909     936 ..     904     940 .. 0.92
   8 !    9.1   0.0    0.0013         1       1      42 []    1176    1217 ..    1176    1217 .. 0.98

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 1.2
      TPR_11  7 qGkyeeAieaYkkAlkldPdnaeayynLGlayykqG 42
                +Gk +eA  +Y +A +++ ++ +a+ +L  +y kqG
  EEA19000.1 50 LGKPDEAESSYLAASRIKDKDKTAWQGLITLYEKQG 85
                788899999********9999999888877777776 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.14
      TPR_11   9 kyeeAieaYkkAlkldPdnaeayynLG 35 
                 +yeeA   +++A + dP+n+ + ++L+
  EEA19000.1 442 DYEEAYHFLQQARERDPSNVKIRSELA 468
                 69999999*************999885 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 4.1
      TPR_11  12 eAieaYkkAlkldPdnaeayynLGlayy 39 
                 +A +++ + ++ d ++a ay  LG +yy
  EEA19000.1 528 GAYASFLASIQADLNYAPAYTRLG-IYY 554
                 67788888899999**********.555 PP

  == domain 4  score: 17.7 bits;  conditional E-value: 2.7e-06
      TPR_11   7 qGkyeeAieaYkkAlkldPdnaeayynLGlayykqG 42 
                 +++y+++i +Y++Al+++P +   + +LG+ y++ G
  EEA19000.1 636 KQQYTKSIVSYQAALRISPGDYHSWVGLGESYHNSG 671
                 78*******************************987 PP

  == domain 5  score: 12.6 bits;  conditional E-value: 0.00011
      TPR_11   2 dayyeqGkyeeAieaYkkAlkldPd 26 
                 ++ +e+G+y++Ai +Y+  l+++P+
  EEA19000.1 707 NVKRELGEYDDAIGRYEDVLAIRPN 731
                 8889********************8 PP

  == domain 6  score: -2.5 bits;  conditional E-value: 5.5
      TPR_11  14 ieaYkkAlkldPd 26 
                 i aYk+A+  + +
  EEA19000.1 857 ILAYKRAVYVSAN 869
                 6677777644444 PP

  == domain 7  score: 12.6 bits;  conditional E-value: 0.00011
      TPR_11  10 yeeAieaYkkAlkldPdnaeayynLGla 37 
                 +++Ai ++k+A++l   n e+++ LG++
  EEA19000.1 909 LKGAIRCFKQAIELEAGNSEFWNSLGVV 936
                 679***********************97 PP

  == domain 8  score: 9.1 bits;  conditional E-value: 0.0013
      TPR_11    1 GdayyeqGkyeeAieaYkkAlkldPdnaeayynLGlayykqG 42  
                  G ayy +   ++Ai  ++ Al   ++++e+ + L+++++++G
  EEA19000.1 1176 GLAYYYLKSMDQAIDMFRDALHEAENDPEVVCLLAQVLWAKG 1217
                  89*************************************998 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.2     0.065        50      33      79 ..      13      60 ..       5      63 .. 0.91
   2 ?    3.1   0.0      0.14   1.1e+02      21      48 ..     339     369 ..     322     374 .. 0.72
   3 !    9.4   0.0    0.0016       1.2       4      65 ..     408     470 ..     406     487 .. 0.79
   4 ?    0.6   0.0      0.84   6.5e+02      29      71 ..     467     511 ..     462     513 .. 0.82
   5 ?    5.6   0.1     0.024        19      29      80 ..     663     723 ..     635     725 .. 0.64
   6 ?   -2.2   0.0       6.5   5.1e+03      53      80 ..    1071    1098 ..    1058    1100 .. 0.68
   7 !    9.2   0.0    0.0018       1.4       2      66 ..    1134    1213 ..    1128    1220 .. 0.82

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.065
                HHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHHH CS
      ANAPC3 33 lylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaaL 79
                 + +++++ A   ++++ + +s++  +++ ++ ++ kL+k +eA++ +
  EEA19000.1 13 ALDSKDFELAASKAKDLiDRDSTNYHAHVFLGLAQDKLGKPDEAESSY 60
                578899***********9**************************9876 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.14
                 --HHHHHHH...HHHHHHTT-HHHHHHHHHC CS
      ANAPC3  21 espedayll...AlclylngqykrAyellrk 48 
                 +s++++ ++   A+ ++++++y +A e++rk
  EEA19000.1 339 QSSDSIIAHrvmAELYLNLEEYASAVEVARK 369
                 5555555555558888888889888888876 PP

  == domain 3  score: 9.4 bits;  conditional E-value: 0.0016
                 -HHHHHHHHHHHH.HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHH CS
      ANAPC3   4 nyknAiflaerllaaetespedayllAlclylngqykrAyellrka.klnskslgcrylfAqc 65 
                 n+ +A  ++e +l++++++ + ++  +l l ++ +y++Ay++l++a + ++++ ++r  +A c
  EEA19000.1 408 NHPEAKGIFESILKRKPKNTKCLLGIGLILEEDHDYEEAYHFLQQArERDPSNVKIRSELAWC 470
                 5667777888899888888888888899999***************88888888888766666 PP

  == domain 4  score: 0.6 bits;  conditional E-value: 0.84
                 HHHHHHHTT-HHHHHHHHHCT.SHHHC-H.HHHHHHHHHHHHTT- CS
      ANAPC3  29 lAlclylngqykrAyellrka.klnsksl.gcrylfAqcllkLkk 71 
                 lA c  lng+ ++ +e l++   + + ++ ++r  +A+ l+ +++
  EEA19000.1 467 LAWCTALNGDLESGLEMLQDVlAEIEDDEnQSREFKAEILYRIGH 511
                 899****************99755554446999999999998887 PP

  == domain 5  score: 5.6 bits;  conditional E-value: 0.024
                 HHHHHHHTT-HHHHHHHHHCTSHHHC-H.........HHHHHHHHHHHHTT-HHHHHHHH- CS
      ANAPC3  29 lAlclylngqykrAyellrkaklnsksl.........gcrylfAqcllkLkkyeeAiaaLe 80 
                 l++++ ++g+y  A + ++ a+  +++l          + y +A +  +L++y++Ai  +e
  EEA19000.1 663 LGESYHNSGRYIAATKAFEHAEALESTLsksessniwFSKYMLANVKRELGEYDDAIGRYE 723
                 5666666666655555555553333333344455557899****************97665 PP

  == domain 6  score: -2.2 bits;  conditional E-value: 6.5
                  HC-HHHHHHHHHHHHHTT-HHHHHHHH- CS
      ANAPC3   53 skslgcrylfAqcllkLkkyeeAiaaLe 80  
                  ++ l    l A  +  +++y +A++aL+
  EEA19000.1 1071 PSALSFEHLSALFAERIGEYAQAESALG 1098
                  5555555666777778899999999997 PP

  == domain 7  score: 9.2 bits;  conditional E-value: 0.0018
                  TT-HHHHHHHHHHHH..............HHH--HHHHHHH.HHHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHH CS
      ANAPC3    2 qnnyknAiflaerll.............aaetespedayll.AlclylngqykrAyellrka.klnskslgcrylfAqcl 66  
                  ++ y+ A+  ae++l              + t    +a+l  +l++y ++  ++A++ +r+a  ++++++++  l+Aq+l
  EEA19000.1 1134 NHEYDQAVEKAELALtlsgddglttpdpGMVTSLRLSAHLTaGLAYYYLKSMDQAIDMFRDAlHEAENDPEVVCLLAQVL 1213
                  6788888888888888888888876654355555566777659*******************99999999**99999987 PP

>> TPR_6  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0       1.6   1.3e+03       6      22 ..      43      59 ..      39      63 .. 0.86
   2 ?   -1.0   0.1       4.6   3.6e+03       6      24 ..     350     368 ..     350     369 .. 0.87
   3 ?    1.1   0.0         1   7.9e+02       9      32 ..     402     425 ..     396     426 .. 0.78
   4 ?    6.4   0.0      0.02        15       2      32 ..     429     459 ..     428     460 .. 0.93
   5 ?    3.0   0.0      0.25   1.9e+02       3      21 ..     506     524 ..     504     536 .. 0.75
   6 ?   -0.6   0.1       3.4   2.7e+03       5      25 ..     549     570 ..     545     573 .. 0.74
   7 ?    1.3   0.0      0.89   6.9e+02       6      31 ..     629     654 ..     627     656 .. 0.85
   8 ?   -2.0   0.0       9.7   7.6e+03       5      24 ..     662     681 ..     659     681 .. 0.83
   9 !   10.7   0.0   0.00086      0.67       4      32 ..     703     731 ..     701     732 .. 0.95
  10 ?   -0.8   0.0       4.1   3.2e+03       3      14 ..     878     896 ..     876     921 .. 0.69
  11 ?   -0.7   0.0       3.7   2.9e+03       2      24 ..     996    1018 ..     995    1018 .. 0.78
  12 ?   -2.0   0.0        10   7.8e+03       6      24 ..    1127    1145 ..    1126    1149 .. 0.78
  13 ?    6.1   0.2     0.026        20       2      28 ..    1171    1197 ..    1170    1200 .. 0.87

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 1.6
                HHHHHHHHHHHHHHHHH CS
       TPR_6  6 lalsyrklgdtdkAlea 22
                l+l++ klg++d+A   
  EEA19000.1 43 LGLAQDKLGKPDEAESS 59
                89*****99****9765 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 4.6
                 HHHHHHHHHHHHHHHHHHH CS
       TPR_6   6 lalsyrklgdtdkAleale 24 
                 +a++y++l +++ A+e  +
  EEA19000.1 350 MAELYLNLEEYASAVEVAR 368
                 799****88*****99876 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 1
                 HHHH.HHHHHHHHHHHHHHHHH-TT CS
       TPR_6   9 syrk.lgdtdkAlealerlikeYPd 32 
                 sy++   ++ +A+ ++e+++k+ P+
  EEA19000.1 402 SYQSpR-NHPEAKGIFESILKRKPK 425
                 455555.899**********99665 PP

  == domain 4  score: 6.4 bits;  conditional E-value: 0.02
                 HHHHHHHHHHH.HHHHHHHHHHHHHHHHH-TT CS
       TPR_6   2 Alyklalsyrk.lgdtdkAlealerlikeYPd 32 
                 +l+ ++l +++   d+++A   l++ +++ P 
  EEA19000.1 429 CLLGIGLILEEdH-DYEEAYHFLQQARERDPS 459
                 6999*******99.***************996 PP

  == domain 5  score: 3.0 bits;  conditional E-value: 0.25
                 HHHHHHHHHHHHHHHHHHH CS
       TPR_6   3 lyklalsyrklgdtdkAle 21 
                 ly+++ ++ +l+ +++A++
  EEA19000.1 506 LYRIGHCQWELDPSSAARK 524
                 9**********55556655 PP

  == domain 6  score: -0.6 bits;  conditional E-value: 3.4
                 HHHHHHHH.HHHHHHHHHHHHH CS
       TPR_6   5 klalsyrk.lgdtdkAlealer 25 
                 +l+  y    +d+++A++ + +
  EEA19000.1 549 RLGIYYADyKKDKARAKRCFHK 570
                 6666677656799999999976 PP

  == domain 7  score: 1.3 bits;  conditional E-value: 0.89
                 HHHHHHH.HHHHHHHHHHHHHHHHH-T CS
       TPR_6   6 lalsyrk.lgdtdkAlealerlikeYP 31 
                 l+  +++ + +++k++  ++  ++  P
  EEA19000.1 629 LGVVQLNkQ-QYTKSIVSYQAALRISP 654
                 688899845.***********999877 PP

  == domain 8  score: -2.0 bits;  conditional E-value: 9.7
                 HHHHHHHHHHHHHHHHHHHH CS
       TPR_6   5 klalsyrklgdtdkAleale 24 
                  l++sy + g++ +A +a+e
  EEA19000.1 662 GLGESYHNSGRYIAATKAFE 681
                 69*****9779999988886 PP

  == domain 9  score: 10.7 bits;  conditional E-value: 0.00086
                 HHHHHHHHHHHHHHHHHHHHHHHHHH-TT CS
       TPR_6   4 yklalsyrklgdtdkAlealerlikeYPd 32 
                 y+la   r+lg++d+A+  +e+++   P+
  EEA19000.1 703 YMLANVKRELGEYDDAIGRYEDVLAIRPN 731
                 99*******9**************99998 PP

  == domain 10  score: -0.8 bits;  conditional E-value: 4.1
                 HHHHHHHHHHH.......H CS
       TPR_6   3 lyklalsyrkl.......g 14 
                  y+l+++ +++        
  EEA19000.1 878 WYNLGWAEYRAyrciegeP 896
                 6999999998756666542 PP

  == domain 11  score: -0.7 bits;  conditional E-value: 3.7
                  HHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6    2 AlyklalsyrklgdtdkAleale 24  
                  A + ++   +  gd+++A+++++
  EEA19000.1  996 AWLGQGIVALLFGDPSEARALFR 1018
                  6677777777756*******996 PP

  == domain 12  score: -2.0 bits;  conditional E-value: 10
                  HHHHHHH.HHHHHHHHHHHH CS
       TPR_6    6 lalsyrk.lgdtdkAleale 24  
                  +a+ +++   ++d+A+e  e
  EEA19000.1 1127 IARVHLAnH-EYDQAVEKAE 1145
                  688888767.9****99665 PP

  == domain 13  score: 6.1 bits;  conditional E-value: 0.026
                  HHHHHHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6    2 AlyklalsyrklgdtdkAlealerlik 28  
                  A + ++l+y+ l+  d+A++++++ + 
  EEA19000.1 1171 AHLTAGLAYYYLKSMDQAIDMFRDALH 1197
                  567789*****99*********99875 PP

>> TPR_4  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.5   0.0    0.0094       7.3       2      21 ..      38      57 ..      37      59 .. 0.94
   2 ?    0.8   0.0       1.4   1.1e+03       3      25 ..     346     368 ..     345     369 .. 0.92
   3 ?    0.0   0.0       2.5     2e+03       4      20 ..     660     676 ..     658     678 .. 0.87
   4 ?    0.2   0.0       2.1   1.7e+03       5      20 ..     703     718 ..     700     722 .. 0.92
   5 !    8.4   0.2     0.005       3.9       3      25 ..     996    1018 ..     994    1019 .. 0.91
   6 ?   -1.6   0.0       8.2   6.4e+03       5      13 ..    1207    1215 ..    1203    1217 .. 0.79

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0094
       TPR_4  2 rallaLArallalGdldeAr 21
                +a+++L+ a+  lG +deA+
  EEA19000.1 38 HAHVFLGLAQDKLGKPDEAE 57
                79*****************8 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 1.4
       TPR_4   3 allaLArallalGdldeAralle 25 
                 a+ ++A+++l l +++ A ++++
  EEA19000.1 346 AHRVMAELYLNLEEYASAVEVAR 368
                 8999***************9998 PP

  == domain 3  score: 0.0 bits;  conditional E-value: 2.5
       TPR_4   4 llaLArallalGdldeA 20 
                  ++L++ ++  G++ +A
  EEA19000.1 660 WVGLGESYHNSGRYIAA 676
                 578**********9887 PP

  == domain 4  score: 0.2 bits;  conditional E-value: 2.1
       TPR_4   5 laLArallalGdldeA 20 
                 ++LA +  +lG++d+A
  EEA19000.1 703 YMLANVKRELGEYDDA 718
                 789***********99 PP

  == domain 5  score: 8.4 bits;  conditional E-value: 0.005
       TPR_4    3 allaLArallalGdldeAralle 25  
                  a l+++ ++l+ Gd+ eAral++
  EEA19000.1  996 AWLGQGIVALLFGDPSEARALFR 1018
                  78999****************98 PP

  == domain 6  score: -1.6 bits;  conditional E-value: 8.2
       TPR_4    5 laLAralla 13  
                   +LA++l+a
  EEA19000.1 1207 CLLAQVLWA 1215
                  68******8 PP

>> DUF2989  Protein of unknown function (DUF2989)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.0     0.034        26     139     199 ..     393     449 ..     375     451 .. 0.89
   2 ?    0.2   0.0      0.68   5.3e+02     126     180 ..     447     506 ..     441     515 .. 0.79
   3 !    8.4   0.2    0.0021       1.6     120     190 ..     525     592 ..     521     598 .. 0.75
   4 ?    1.8   0.0      0.23   1.8e+02     140     187 ..    1171    1213 ..    1166    1224 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.034
     DUF2989 139 eaelqlalAtyylkrdaekakklllkaLelskkddkvdpeillsLasiyqkqknlekaYlw 199
                 + +l +al +y + r++ +ak +++++L+   k+    ++ ll++  i ++ +++e+aY +
  EEA19000.1 393 NTTLATALISYQSPRNHPEAKGIFESILKRKPKN----TKCLLGIGLILEEDHDYEEAYHF 449
                 567899999*******************988777....99*******************77 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.68
     DUF2989 126 kkflalekqgeleeaelqlalAtyy.lkrdaekakklllkaLelskkdd....kvdpeil 180
                  +fl++++++  ++++++++lA    l+ d e  +++l+++L+ +++d+    ++++eil
  EEA19000.1 447 YHFLQQARERDPSNVKIRSELAWCTaLNGDLESGLEMLQDVLAEIEDDEnqsrEFKAEIL 506
                 579999999999**********865268899************99999634445566655 PP

  == domain 3  score: 8.4 bits;  conditional E-value: 0.0021
     DUF2989 120 gdqeAlkkflalekqgeleeaelqlalAtyyl..krdaekakklllkaLelskkddkvdpeillsLasiyqkq 190
                 + + A  +fla   q  l+ a   ++l+ yy+  k+d+++ak+ ++ka+els+++    +e    La+ + ++
  EEA19000.1 525 NRNGAYASFLAS-IQADLNYAPAYTRLGIYYAdyKKDKARAKRCFHKAFELSSSE----IEAAERLAKAFANK 592
                 556677777765.46789999999*******6337899999***********999....55555555555544 PP

  == domain 4  score: 1.8 bits;  conditional E-value: 0.23
     DUF2989  140 aelqlalAtyylkrdaekakklllkaLelskkddkvdpeillsLasiy 187 
                  a+l + lA yylk+  ++a++++++aL+  ++d    pe++  La++ 
  EEA19000.1 1171 AHLTAGLAYYYLKS-MDQAIDMFRDALHEAEND----PEVVCLLAQVL 1213
                  57888899999886.6789********988877....77776666665 PP

>> TPR_9  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.1       3.3   2.6e+03      19      49 ..     328     364 ..     317     365 .. 0.72
   2 ?    4.9   0.0     0.038        30       5      62 ..     403     460 ..     400     496 .. 0.92
   3 !    7.0   0.0    0.0081       6.3       7      55 ..     635     683 ..     630     693 .. 0.87
   4 ?   -1.4   0.1       3.4   2.7e+03      12      50 ..     977    1015 ..     951    1019 .. 0.68
   5 ?    3.5   0.2     0.099        77      28      70 ..    1168    1210 ..    1127    1212 .. 0.70

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 3.3
       TPR_9  19 erllll......aPddpeerrdRGlllaqlGclsaAl 49 
                 +rl+l+       +d++  +r  + l+  l+ ++ A+
  EEA19000.1 328 DRLILMsngleqSSDSIIAHRVMAELYLNLEEYASAV 364
                 4444447777777888888899999999999999997 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.038
       TPR_9   5 aireedweralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalapda 62 
                 +++++++++a  + e++l  +P+    ++  Gl+l++  ++++A   L+++ + +p++
  EEA19000.1 403 YQSPRNHPEAKGIFESILKRKPKNTKCLLGIGLILEEDHDYEEAYHFLQQARERDPSN 460
                 889999999999**********************************999999999965 PP

  == domain 3  score: 7.0 bits;  conditional E-value: 0.0081
       TPR_9   7 reedweralavverllllaPddpeerrdRGlllaqlGclsaAladLeay 55 
                 +++++ + +  ++  l + P d + +   G  ++ +G++ aA +++e++
  EEA19000.1 635 NKQQYTKSIVSYQAALRISPGDYHSWVGLGESYHNSGRYIAATKAFEHA 683
                 566677777778999********************************97 PP

  == domain 4  score: -1.4 bits;  conditional E-value: 3.4
       TPR_9   12 eralavverllllaPddpeerrdRGlllaqlGclsaAla 50  
                  + a ++  r    +Pd +  ++  G++    G++s+A+a
  EEA19000.1  977 QLANEAFTRGQSADPDYAPAWLGQGIVALLFGDPSEARA 1015
                  444444444445578888888888888888888888876 PP

  == domain 5  score: 3.5 bits;  conditional E-value: 0.099
       TPR_9   28 dpeerrdRGlllaqlGclsaAladLeaylalapdapdaeaira 70  
                  + + ++  Gl+++ l  + +A++ +  +l+ a+++p++  + a
  EEA19000.1 1168 RLSAHLTAGLAYYYLKSMDQAIDMFRDALHEAENDPEVVCLLA 1210
                  45667789************************99998766655 PP

>> TPR_22  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0     6e-05     0.047      15      91 .]     133     206 ..     127     206 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 6e-05
      TPR_22  15 tpqealkkLlkilskkeqeevsklvsrerlklsandpdyqikinslaWevykdsevdelynqLvnivddDeeRrkle 91 
                 +p ++ ++L+++++++e+e + + + + r +l a   + +  +     e  ++ e++e+y+ L++ ++dD  R+++e
  EEA19000.1 133 HPADTYSRLIELTEAEEKEFINREIGERRTRLGARIDQVTAEVKR---EALSNPELEEYYRGLIDWTNDDGIRHQTE 206
                 5789999**********************9999988777766655...6689*******************999877 PP

>> HrpB1_HrpK  Bacterial type III secretion protein (HrpB1_HrpK)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.0    0.0062       4.9      37      94 ..     419     476 ..     391     498 .. 0.81
   2 ?   -3.5   0.0       9.9   7.7e+03      84     104 ..     736     755 ..     711     773 .. 0.58
   3 ?    4.5   0.1     0.033        25      59     107 ..    1183    1231 ..    1170    1251 .. 0.82

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0062
  HrpB1_HrpK  37 lrvLrPevaeldllegvlliergrweeAlrlLreveaeasgtpyakaLlAlcLaalrD 94 
                 +   +P++++  l  g++l e +++eeA + L++  ++ ++     + lA+c a  +D
  EEA19000.1 419 ILKRKPKNTKCLLGIGLILEEDHDYEEAYHFLQQARERDPSNVKIRSELAWCTALNGD 476
                 555578999999999999999*****************99999999999***999888 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 9.9
  HrpB1_HrpK  84 LlAlcLaalrDeeWrayAeev 104
                 ++Al L++l +++W+ +   +
  EEA19000.1 736 MIAL-LQTLTESSWKNLDTGL 755
                 3443.7788888888765555 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.033
  HrpB1_HrpK   59 grweeAlrlLreveaeasgtpyakaLlAlcLaalrDeeWrayAeevles 107 
                  ++++ A+ ++r+  +ea++ p +  LlA +L a++ ee r +A e l +
  EEA19000.1 1183 KSMDQAIDMFRDALHEAENDPEVVCLLAQVLWAKGGEEERNVAREQLFE 1231
                  78999*********************************99999886643 PP

>> Sel1  Sel1 repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.0     0.094        74      16      36 ..     434     456 ..     429     458 .. 0.74
   2 ?    7.4   0.3    0.0094       7.3       2      36 ..     545     574 ..     544     576 .. 0.80

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.094
        Sel1  16 Gl.g.vpkDpekAiewyekAAeq 36 
                 Gl   ++ D+e+A++++++A e+
  EEA19000.1 434 GLiLeEDHDYEEAYHFLQQARER 456
                 443335669***********776 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0094
        Sel1   2 eAmyrLGmfylylnGlgvpkDpekAiewyekAAeq 36 
                  A+ rLG +y      + +kD+ +A ++++kA e+
  EEA19000.1 545 PAYTRLGIYY----A-DYKKDKARAKRCFHKAFEL 574
                 6899999444....3.48**************776 PP

>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0       1.6   1.2e+03       8      25 ..      43      60 ..      43      66 .. 0.84
   2 ?   -0.7   0.0       1.9   1.5e+03       9      32 ..     351     374 ..     349     377 .. 0.86
   3 ?   -2.2   0.0       5.7   4.4e+03       5      21 ..     547     564 ..     546     574 .. 0.58
   4 ?    3.9   0.0     0.066        51       8      28 ..     663     683 ..     662     683 .. 0.94
   5 ?    9.9   0.0   0.00085      0.66       8      32 ..     705     729 ..     701     734 .. 0.94
   6 ?   -1.7   0.0         4   3.1e+03      15      30 ..    1007    1022 ..    1001    1025 .. 0.79
   7 ?   -2.4   0.5       6.5   5.1e+03       7      26 ..    1126    1145 ..    1121    1150 .. 0.77
   8 ?   -0.0   0.2       1.1   8.9e+02       9      29 ..    1176    1196 ..    1175    1200 .. 0.92

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 1.6
      TPR_10  8 LanalrqrgrydeAeall 25
                L+ a  ++g+ deAe  +
  EEA19000.1 43 LGLAQDKLGKPDEAESSY 60
                8899999*******9765 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 1.9
      TPR_10   9 analrqrgrydeAealleealair 32 
                 a ++ ++ +y+ A++ +++ + i 
  EEA19000.1 351 AELYLNLEEYASAVEVARKGITII 374
                 8899***********999988875 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 5.7
      TPR_10   5 lnNLanal.rqrgrydeA 21 
                 ++ L++++    ++ ++A
  EEA19000.1 547 YTRLGIYYaDYKKDKARA 564
                 677888884444555555 PP

  == domain 4  score: 3.9 bits;  conditional E-value: 0.066
      TPR_10   8 LanalrqrgrydeAealleea 28 
                 L+  +++ gry +A + +e+a
  EEA19000.1 663 LGESYHNSGRYIAATKAFEHA 683
                 8999************99987 PP

  == domain 5  score: 9.9 bits;  conditional E-value: 0.00085
      TPR_10   8 LanalrqrgrydeAealleealair 32 
                 Lan+ r++g+yd+A   +e++lair
  EEA19000.1 705 LANVKRELGEYDDAIGRYEDVLAIR 729
                 9**********************97 PP

  == domain 6  score: -1.7 bits;  conditional E-value: 4
      TPR_10   15 rgrydeAealleeala 30  
                   g+  eA+al+++  +
  EEA19000.1 1007 FGDPSEARALFRHGFE 1022
                  58999******98665 PP

  == domain 7  score: -2.4 bits;  conditional E-value: 6.5
      TPR_10    7 NLanalrqrgrydeAealle 26  
                  ++a+++ +  +yd+A++ +e
  EEA19000.1 1126 DIARVHLANHEYDQAVEKAE 1145
                  68999999999999997555 PP

  == domain 8  score: -0.0 bits;  conditional E-value: 1.1
      TPR_10    9 analrqrgrydeAealleeal 29  
                  + a++ ++  d+A +++++al
  EEA19000.1 1176 GLAYYYLKSMDQAIDMFRDAL 1196
                  789****************98 PP

>> DUF3856  Domain of Unknown Function (DUF3856)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0      0.89     7e+02      56      82 ..     345     371 ..     320     400 .. 0.84
   2 ?   -0.6   0.1       1.6   1.3e+03      83     121 ..     658     697 ..     623     718 .. 0.49
   3 ?    6.4   0.0     0.011       8.9      17      46 ..     748     777 ..     737     800 .. 0.85
   4 ?    1.1   0.1      0.49   3.9e+02      55     126 ..    1121    1195 ..    1118    1202 .. 0.77

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.89
                 HHHHHHHHHHHHTT-HHHHHHHHHHHH CS
     DUF3856  56 lchaglsealaklgrydealesadkal 82 
                 ++h +++e +++l +y +a+e a k++
  EEA19000.1 345 IAHRVMAELYLNLEEYASAVEVARKGI 371
                 678899999999999999998888775 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 1.6
                 HHHHHH--TTSTHHHHHHHH..HHHHHHHHHHTT-HHHHHH CS
     DUF3856  83 ryfnrrGeleqdeGklWiaa..vfsravaleelGrkdealk 121
                 + +   Ge  ++ G+ +iaa   f++a ale++ +k+e+ +
  EEA19000.1 658 HSWVGLGESYHNSGR-YIAAtkAFEHAEALESTLSKSESSN 697
                 333344555555554.3333124667777777766666554 PP

  == domain 3  score: 6.4 bits;  conditional E-value: 0.011
                 HHHHHHT-HHHHHHHHHHHHHHHTTS-TTS CS
     DUF3856  17 ekqleegayeeaaasyrkalevsrtipaee 46 
                  k+l  g +++aa+s+++ale++ ++++e 
  EEA19000.1 748 WKNLDTGLFNDAAKSAHRALEIAIAMAKET 777
                 47899********************99885 PP

  == domain 4  score: 1.1 bits;  conditional E-value: 0.49
                  HHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHH--TTSTHH...HHHHHHHHHHHHHHHHTT-HHHHHHHHHHH CS
     DUF3856   55 alchaglsealaklgrydealesadkalryfnrrGeleqdeG...klWiaavfsravaleelGrkdealkafrma 126 
                  al+ a ++   +   +yd+a+e a+ al      G    d G   +l ++a ++ + a+  l + d+a+++fr a
  EEA19000.1 1121 ALANADIARVHLANHEYDQAVEKAELALTLSGDDGLTTPDPGmvtSLRLSAHLTAGLAYYYLKSMDQAIDMFRDA 1195
                  667777777777888999999999999998888888888877443466778888888888888888888888766 PP

>> TPR_20  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.1    0.0013         1      11      58 ..     450     497 ..     441     508 .. 0.89
   2 ?   -0.5   0.3         2   1.6e+03      33      69 ..     521     573 ..     513     592 .. 0.74
   3 ?    2.1   0.0      0.33   2.6e+02       5      44 ..     640     679 ..     636     696 .. 0.89
   4 ?    6.8   0.3     0.011       8.4       5      54 ..    1186    1238 ..    1183    1287 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0013
      TPR_20  11 leaalaanpddldarldlAlallaagryeeAleqLleilkrdrkwedd 58 
                 l++a + +p+++++r +lA   + +g+ e  le L ++l++  ++e++
  EEA19000.1 450 LQQARERDPSNVKIRSELAWCTALNGDLESGLEMLQDVLAEIEDDENQ 497
                 89999*********************************9987776554 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 2
      TPR_20  33 laagryeeAleqLleilkrdrkw................eddaarkqllkife 69 
                 +a++++  A + +l+ +++d+++                ++ +a++ + k fe
  EEA19000.1 521 AARKNRNGAYASFLASIQADLNYapaytrlgiyyadykkDKARAKRCFHKAFE 573
                 57788889999999999999999777777777777774444455555666666 PP

  == domain 3  score: 2.1 bits;  conditional E-value: 0.33
      TPR_20   5 apelaeleaalaanpddldarldlAlallaagryeeAleq 44 
                 ++++ + +aal  +p d+   + l + ++  gry +A ++
  EEA19000.1 640 TKSIVSYQAALRISPGDYHSWVGLGESYHNSGRYIAATKA 679
                 56778899**************************998765 PP

  == domain 4  score: 6.8 bits;  conditional E-value: 0.011
      TPR_20    5 apelaeleaalaanpddldarldlAlallaagryee...AleqLleilkrdrk 54  
                  ++ ++ +++al ++ +d +  + lA++l a+g +ee   A eqL+e ++++ +
  EEA19000.1 1186 DQAIDMFRDALHEAENDPEVVCLLAQVLWAKGGEEErnvAREQLFESVEKNPE 1238
                  56788899*********************99977766669********99876 PP

>> TerB  Tellurite resistance protein TerB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.1    0.0016       1.2      84     138 ..     168     223 ..     133     228 .. 0.76
   2 ?    3.5   0.7      0.08        62      49      87 ..     561     600 ..     555     607 .. 0.83
   3 ?   -0.3   0.2       1.2   9.3e+02      15      49 ..    1231    1261 ..    1191    1310 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0016
        TerB  84 leqftralkrk.lspeqrraliealweiAlADGeldeaEdavlrrvaelLglspad 138
                  +q+t+++kr+ ls +++++  ++l+     DG ++++E+++l+r+ +lL + p+d
  EEA19000.1 168 IDQVTAEVKREaLSNPELEEYYRGLIDWTNDDGIRHQTEERLLQRAYDLLSVLPQD 223
                 5677777776515599999999999999999********************98887 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.08
        TerB  49 rqafrellksrfglspeeakallelfeeaeee.avdleqf 87 
                 +++ +++++++f+ls  e++a+ +l++++ ++ + dl ++
  EEA19000.1 561 KARAKRCFHKAFELSSSEIEAAERLAKAFANKqEWDLVEA 600
                 7899**********************99887645666655 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 1.2
        TerB   15 gaektdaakeafalalaallaevakaDgqvsesEr 49  
                  ++ ++ ++    +l +++ll  +a  Dg+ ++ E 
  EEA19000.1 1231 ESVEKNPE----HLGAVTLLGAIALLDGDEDAIEA 1261
                  44444444....78888888888888888887774 PP

>> DUF2225  Uncharacterized protein conserved in bacteria (DUF2225)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.2       7.9   6.2e+03     120     148 ..     546     575 ..     537     588 .. 0.54
   2 ?    0.7   0.0      0.48   3.7e+02     143     193 ..     675     727 ..     629     735 .. 0.76
   3 ?    7.5   0.1     0.004       3.1     116     163 ..     873     931 ..     847     957 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 7.9
     DUF2225 120 lalrlAWlyrdked.eekeklflkkAlely 148
                  + rl+ +y d ++ ++  k+  +kA el 
  EEA19000.1 546 AYTRLGIYYADYKKdKARAKRCFHKAFELS 575
                 556666666655441334444555555443 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.48
     DUF2225 143 kAlelyk..eayekesfpvegideatvlYLiaeLerrlgnkeealrwlskvig 193
                  A++ ++  ea+e++ +++e  +     Y++a+ +r lg++++a+  ++ v+ 
  EEA19000.1 675 AATKAFEhaEALESTLSKSESSNIWFSKYMLANVKRELGEYDDAIGRYEDVLA 727
                 5666665114444444555555555578***************9998888775 PP

  == domain 3  score: 7.5 bits;  conditional E-value: 0.004
     DUF2225 116 kkAklalrlAWl.yrdked..........eekeklflkkAlelykeayekesfpvegid 163
                  +A+ + +l+W  yr              +   k+flk A++++k+a+e e  ++e  +
  EEA19000.1 873 AQAVSWYNLGWAeYRAYRCiegepntkkeKRYTKKFLKGAIRCFKQAIELEAGNSEFWN 931
                 6777777777754333333334666665578889*****************99887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1398 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       507  (0.0282782); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                        23  (0.00128284); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              23  [number of targets reported over threshold]
# CPU time: 0.93u 0.29s 00:00:01.22 Elapsed: 00:00:00.52
# Mc/sec: 8129.79
//
Query:       EEA19001.1  [L=756]
Description: glycosyl hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.9e-22   79.0   0.0    8.2e-22   77.6   0.0    1.8  1  Glyco_hydro_5_C  Glycoside hydrolase family 5 C-terminal doma
    9.7e-09   35.0   6.8    3.8e-07   29.8   4.4    2.6  2  Cellulase        Cellulase (glycosyl hydrolase family 5)
  ------ inclusion threshold ------
      0.044   13.7   0.3        0.1   12.5   0.3    1.6  1  EKLF_TAD1        Erythroid krueppel-like transcription factor


Domain annotation for each model (and alignments):
>> Glyco_hydro_5_C  Glycoside hydrolase family 5 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.6   0.0   1.4e-25   8.2e-22       1      87 []     637     726 ..     637     726 .. 0.94

  Alignments for each domain:
  == domain 1  score: 77.6 bits;  conditional E-value: 1.4e-25
  Glyco_hydro_5_C   1 RPyPakvaGtplsfsfdlktgeftlewtadkssaedseTeIflPelhyp.kgrkvevsggkwey....deerqtlyvvwahsepgeqhtvtV 87 
                      RP++++++G++l+++fdlk ++ftl++ adk ++++++TeI+lPe+h+p  +++v+vsggkw++    +++   ++++w+h e g+q  +tV
       EEA19001.1 637 RPSAIYTSGDLLNHGFDLKGCKFTLSLYADKPTTQEAPTEIYLPEFHFPaAEISVTVSGGKWTIetreESSYSFQVLKWWHGE-GDQ-DITV 726
                      9************************************************999************887555778899*******.999.8887 PP

>> Cellulase  Cellulase (glycosyl hydrolase family 5)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.8   4.4   6.3e-11   3.8e-07      30     133 ..      73     250 ..      58     267 .. 0.70
   2 !    4.5   0.0    0.0034        20     149     206 ..     380     434 ..     367     525 .. 0.81

  Alignments for each domain:
  == domain 1  score: 29.8 bits;  conditional E-value: 6.3e-11
                 HHHHT-SEEEEEEECTGGTTSSTTTGCTHHHHHHHHHHHHHHHHTT-EEEEEEESS...........TTT......CSSSSTTTTHHH..HHHH..... CS
   Cellulase  30 vkdagfntvRlpvswgelvenapdykvdenslerveevvkyakenglyvildiHse...........egw......ltkadgnssedt..aeef..... 104
                 ++++g+nt+R  ++w+ + + +  +k+d+++++   ev+  ak+ ++yv+ d+H++           ++w      ++++++n+++++  +        
  EEA19001.1  73 LRKWGYNTIRYIFTWEAIEH-SGPGKYDDEWIAYTIEVLRIAKQYNFYVFMDPHQDvwsrfsggsgaPLWtlyavgFNPENFNKTQAAlvQ--Ntwpnp 168
                 689************77775.55557*****************************988888888888777776666555555555555331..244555 PP

                 .......................................................HHHHHHHH..HHHHTTTTTTEEEESSSS--S CS
   Cellulase 105 .......................................................fkklwtqi..AerykkndevvifelmNEPhg 133
                                                                        +    ++i  A  +  ++ ++++e +NEPh 
  EEA19001.1 169 sefpkmiwstnytrlacqtiftlfwagrdfapkaiidgrniqdylqehfigsckyL---AQKIheAGDL-EDEVIIGWESLNEPHR 250
                 55566666666677777777777777777777777777776666666654443321...2222113333.4455777888888876 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.0034
                 HHHHHHHHHHHHHHTTSSEEEEECHHHHT..BHHHHHCTSGSSSSTTEEEEEEEETTTHH CS
   Cellulase 149 kayaeeaikaIRavgpnrliivegnswsg..nldgavlndPndsqdnliysvHfYgpsdf 206
                 ++++ +  +aIR+v++n +++++ +  +   +l+g++ +dP     n++ + H+Y++   
  EEA19001.1 380 MDHYRAYRDAIRSVHSNSILLIQPPVMEVppKLKGTEDDDP-----NMVHAAHYYDGLTL 434
                 566777889********999999977666334444444455.....89*******97664 PP

>> EKLF_TAD1  Erythroid krueppel-like transcription factor, transactivation 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.3   1.7e-05       0.1       7      18 ..     713     724 ..     711     725 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.7e-05
   EKLF_TAD1   7 LKWWrSEEvQDl 18 
                 LKWW+ E  QD+
  EEA19001.1 713 LKWWHGEGDQDI 724
                 9**********6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (756 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       307  (0.0171231); expected 358.6 (0.02)
Passed bias filter:                      278  (0.0155056); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.45
# Mc/sec: 5019.71
//
Query:       EEA19002.1  [L=731]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-06   27.9   0.3    4.9e-06   25.8   0.0    2.2  2  Fungal_trans  Fungal specific transcription factor domain
  ------ inclusion threshold ------
      0.091   12.7   0.0       0.32   11.0   0.0    1.9  1  T3SS_ExsE     Type III secretion system ExsE


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   0.0   5.5e-10   4.9e-06      12     194 ..     299     479 ..     286     505 .. 0.73
   2 ?   -1.4   0.1      0.11   9.5e+02      35     105 ..     499     572 ..     484     625 .. 0.66

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 5.5e-10
  Fungal_trans  12 fpilhkpsflpktssenssksayasplll..lailalGalfsesetkesnssltses...qefiafplraeilihedfsspssslwilqsLlllely 103
                    p+lh p+f+++ ++    ++a  ++ l+  l++l l  ++s+  + + + ++t      +  + ++l+  i++       +++l +l +L ++ l 
    EEA19002.1 299 HPMLHPPTFYEELNKFWEDPAAVEDDWLAqlLVMLGLSHHMSRGVNITPDEETT--LrqyFRGAETCLKSTIFL------IAPNLLSLRTLCMMVLA 387
                   499999***999955555566667777773355555555555533333222222..224567778888888888......66668999988777766 PP

  Fungal_trans 104 ektss....dralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddlwe 194
                      ++    + +++  ++ +++r+a  +gL+ +p +     +   + +++e+rr+lw +   + + i++ +G p+ l+ s+in++ P++ +d + 
    EEA19002.1 388 RRILGssclELDACGPLMAIVLRMAIGIGLNVDPQHDI---SDSTTLFDREIRRKLWTTMALMGTSISVLTGTPFVLRSSDINTQPPMNLNDTEL 479
                   6666622334444444******************9998...46788889**************************99***********9998665 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.11
  Fungal_trans  35 aspllllailalGalfsesetkesnssltses.......qefiafplraeilihedfsspssslwilqsLlllelyek 105
                   ++++ ++  ++l++  +  +++ s+  + +++        +     l+ + ++h++ s+p +  w   +L++l++y+ 
    EEA19002.1 499 TFSIIVAQSFHLACDTVAHANSPSTHLSYEDVliysvkiKN---LLLETSQFYHPSDSPPLE-DWKQDQLFMLQIYLR 572
                   45555666666666555555555433333333444222211...123666666888888888.788888888888875 PP

>> T3SS_ExsE  Type III secretion system ExsE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   3.5e-05      0.32      10      41 ..     333     364 ..     330     367 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 3.5e-05
                 HHHHHHHHHHCTT-TTHHHHHHHHHHT----G CS
   T3SS_ExsE  10 egLarmLaRnvAgdlrsEqaLQRLlDGdgTPL 41 
                  gL+  ++R+v   +  E++L     G  T L
  EEA19002.1 333 LGLSHHMSRGVNITPDEETTLRQYFRGAETCL 364
                 69*******************99888888877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (731 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       422  (0.0235373); expected 358.6 (0.02)
Passed bias filter:                      344  (0.0191868); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.29s 00:00:00.93 Elapsed: 00:00:00.46
# Mc/sec: 4805.88
//
Query:       EEA19003.1  [L=340]
Description: short-chain dehydrogenase/reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.8e-21   75.4   0.0    1.1e-16   60.8   0.0    2.1  2  adh_short     short chain dehydrogenase
    1.5e-15   57.4   0.2    1.7e-14   54.0   0.2    1.9  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
  ------ inclusion threshold ------
      0.032   14.1   0.1      0.068   13.1   0.0    1.6  2  KR            KR domain


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.8   0.0   1.9e-20   1.1e-16       1     140 [.      41     184 ..      41     195 .. 0.84
   2 !   12.7   0.0   1.1e-05     0.064     146     193 ..     206     254 ..     201     256 .. 0.91

  Alignments for each domain:
  == domain 1  score: 60.8 bits;  conditional E-value: 1.9e-20
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT..TSEEEEEE-TTTSHHHHHHHHHHHHHHH.SSESEEEE---SS--SSGGGC CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee..gakalaiqvDvtdreevealvekavkkl.gkldvLvnNAGitgsgpfsel 96 
                 k+ +v G+++GIG ++a++l   Ga+v++++++ e+  eva+++  +    k++++++++ + e+v+ + +k  +   gk++vL++NAGi  +g  ++ 
  EEA19003.1  41 KTFFVSGGTNGIGVETARALHVTGADVYITGQTRERGTEVAEHIAGDgkPGKVVFLEMNLGSLESVRGVAKKFLEVSgGKVNVLITNAGI--RGYPKDK 137
                 567899***************************************9988889********************9998889***********..4555556 PP

                 SHHHHHHHHHHHTHHHHHHHHHHHHHHH...HCTTEEEEEEEEGGGT CS
   adh_short  97 seeewervievNltgvflltravlpaml...kqssGrIvnvsSvagk 140
                 +++ +e+ + +N  g f l +++ +a+l     +  + v v S ag+
  EEA19003.1 138 TQDGFEQHFGINHLGHFALFQHLKDALLassTPEFNSRVVVLSAAGH 184
                 6666*******************999995552233333445555554 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 1.1e-05
                 BHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBS.SHHHHHHCTH CS
   adh_short 146 vaaYsAsKaavagltrslakelaptgirvnavaPGlvd.Tdmakelrek 193
                 + aY+ sK a + +++++ + +a++g   +av+PGl+  T+++k++ ++
  EEA19003.1 206 GLAYGHSKIANIYMANEIERRFADQGLHATAVNPGLIPgTGLNKKIPPE 254
                 569**********************************99***9998765 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.0   0.2   2.8e-18   1.7e-14       3     211 ..      49     278 ..      47     285 .. 0.84

  Alignments for each domain:
  == domain 1  score: 54.0 bits;  conditional E-value: 2.8e-18
                   TTSHHHHHHHHHHHTT-EEEEEESSGGH.HHHHHHHHHHTT.SEE..EE--TTSHHHHHHHHHHHHHHH.SSEEEEEE-----EGCSS-GGGH-HHH CS
  adh_short_C2   3 asgIGraiAkalaeeGaevvltdlneea.kkrveelaeelg.aev..lecDVtdeeqvealveevvekf.gklDilvnnagiapklkgpfletsree 94 
                    +gIG ++A+al+  Ga+v +t + +e+  + +e +a +++  +v  le++  + e+v+ ++++  e   gk+++l+ nagi         + ++++
    EEA19003.1  49 TNGIGVETARALHVTGADVYITGQTRERgTEVAEHIAGDGKpGKVvfLEMNLGSLESVRGVAKKFLEVSgGKVNVLITNAGIRGY----PKDKTQDG 141
                   58**************************8888888888876544447*****************9999889***********999....57899*** PP

                   HHHHHHHHTHHHHHHHHHHHH.HCTSC.....CEEEEEEEGGGTSB...S.........TTTT...HHHHHHHHHHHHHHHHHHHHGGGTEEEEEEE CS
  adh_short_C2  95 fdraldvnlyslfllakaalp.lmkeg.....gsivnlssvgaerv...v.........pnyn...aygaaKaalealtrylAvelgpkgiRvNavs 170
                   f++ + +n  + f+l ++++  l++++     +++v ls  g +++   +         ++yn   ayg +K a + ++  + + ++++g    av 
    EEA19003.1 142 FEQHFGINHLGHFALFQHLKDaLLASStpefnSRVVVLSAAGHRQSkirFgdynydnrpDEYNpglAYGHSKIANIYMANEIERRFADQGLHATAVN 238
                   *********************8665556889899999999988765322233333333234668899****************************** PP

                   E--BH.CTGGGGSTTHHHHHHHHHHHSTTSS-B-HHHHHHHH CS
  adh_short_C2 171 pgpik.Tlaasgikgfdelleelearaplgrlgtpeevaeaa 211
                   pg+i  T ++++i+  +e  +++ ++a l+ l +  e ++a+
    EEA19003.1 239 PGLIPgTGLNKKIP--PEQVAQMWKMAALRSLLKSAEQGAAT 278
                   ****7478899999..78888888999999999888888776 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   1.1e-05     0.068       2      92 ..      42     131 ..      41     171 .. 0.76
   2 ?   -3.4   0.0       1.3   7.7e+03     159     176 ..     222     240 ..     213     242 .. 0.62

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.1e-05
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-..EEEE----TT-HHHHHHHHHHHHHHS.S---EEEE----- CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealga..evevvaaDvsdkdavealleeikaee.ppikGvihaAgvl 92 
                 t+++ GG+ g+G e+ar l   ga  + +++ + +   + ++  ++++  g   +v ++++ + + ++v+ + +++ +   ++++  i  Ag+ 
  EEA19003.1  42 TFFVSGGTNGIGVETARALHVTGAD-VYITGQTRE---RGTEVAEHIAGDGKpgKVVFLEMNLGSLESVRGVAKKFLEVSgGKVNVLITNAGIR 131
                 6789******************985.777888733...33445555555555559999999999999999999998877779999999999885 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 1.3
                 HHHHH.HHHHHTEEEEEE- CS
          KR 159 laeyr.rsqglpavsinwg 176
                  +e r ++qgl+a+++n g
  EEA19003.1 222 EIERRfADQGLHATAVNPG 240
                 4444326789999999866 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (340 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       271  (0.0151152); expected 358.6 (0.02)
Passed bias filter:                      250  (0.0139439); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.47u 0.24s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 2422.07
//
Query:       EEA19004.1  [L=1236]
Description: nuclear import and export protein Msn5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.8e-11   43.7   6.0    3.3e-10   40.2   1.6    4.2  4  Xpo1       Exportin 1-like protein


Domain annotation for each model (and alignments):
>> Xpo1  Exportin 1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.2   1.6   1.8e-14   3.3e-10       1     140 [.     108     274 ..     108     285 .. 0.92
   2 ?   -2.6   0.0      0.29   5.3e+03      66      94 ..     352     380 ..     340     397 .. 0.68
   3 ?   -4.2   0.0       0.9   1.6e+04     101     115 ..     517     531 ..     504     531 .. 0.82
   4 ?   -1.3   0.0      0.11     2e+03      15      37 ..     788     810 ..     786     835 .. 0.76

  Alignments for each domain:
  == domain 1  score: 40.2 bits;  conditional E-value: 1.8e-14
                 THHHHHHHHHHHHHHHHHHTTTTSTTHHHHHHHHHCT.HHHHHHHHHHHHHHHHHHHTSHTTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC. CS
        Xpo1   1 pkflrnklaealaelflqeypnnWpsffddllsllssspsglelllriLkvlpeEiadfsrskleqerrndlkdllrsnvqkilelllqileqsqskk. 98 
                 p+++rnk+a++ +e +++ ++ +W+s+ +dl++l + s+ + el+l iL +l+e+i+ ++++++++ r +dl+++l + +  ++ + ++  e+ ++ + 
  EEA19004.1 108 PSYYRNKVAQLWTEVAKRSWGIDWNSMDQDLFNLWNGSALHKELVLSILETLSEDIF-YREDTASSLRGTDLNRALVEIFTPLAVFQETFPEREHHRQe 205
                 6899*****************************************************.9***************************9999999999889 PP

                 ...........................HHHHHHHHHHHHHHHHTTTS-HHHHHTSCHHHHHHHHCCSCC CS
        Xpo1  99 ...........................qsselveavLkclsswvswidiglivnnpllnllfqlLsdpe 140
                                            + ++ + ++L +l+s + w   + i+  +++++++++L+++ 
  EEA19004.1 206 irylddgwlsricilineclgsvntsrEAKDCTLKALAVLRSALVWSIPKAIITCDIVTTICRTLTSQI 274
                 ************************999999999999999999999*********99*********4433 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 0.29
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        Xpo1  66 qerrndlkdllrsnvqkilelllqileqs 94 
                 ++++ dl+ + r+ ++ ++e+l++il  +
  EEA19004.1 352 EDKDLDLQSASRTDIPFLFEFLIEILRHQ 380
                 45666677777777777888888887655 PP

  == domain 3  score: -4.2 bits;  conditional E-value: 0.9
                 HHHHHHHHHHHHHHT CS
        Xpo1 101 selveavLkclsswv 115
                  ++vea+Lk +++w+
  EEA19004.1 517 FSVVEATLKGYQKWI 531
                 58999****999997 PP

  == domain 4  score: -1.3 bits;  conditional E-value: 0.11
                 HHHHHTTTTSTTHHHHHHHHHCT CS
        Xpo1  15 lflqeypnnWpsffddllsllss 37 
                 l ++++ n +p+++++ll+l+  
  EEA19004.1 788 LGCALWRNVIPTILPTLLQLIGH 810
                 66788889999999999988865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1236 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       613  (0.0341904); expected 358.6 (0.02)
Passed bias filter:                      512  (0.0285571); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.86u 0.29s 00:00:01.14 Elapsed: 00:00:00.48
# Mc/sec: 7710.04
//
Query:       EEA19005.1  [L=119]
Description: NADH-ubiquinone oxidoreductase subunit GRIM-19, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-22   79.6   0.2    4.4e-22   78.5   0.2    1.6  1  GRIM-19   GRIM-19 protein


Domain annotation for each model (and alignments):
>> GRIM-19  GRIM-19 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.5   0.2   2.4e-26   4.4e-22       3      94 ..       2      93 ..       1     115 [. 0.93

  Alignments for each domain:
  == domain 1  score: 78.5 bits;  conditional E-value: 2.4e-26
                XXXXXXSTTXSXXXXSXXXXXXXSXSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSS CS
     GRIM-19  3 kQdmpPkGGYapinykrklpktllsglsllalviavtavglyavlksnkerrrekiekrsarlailPlllAerdrrylkqlrknrdeeaklm 94
                 QdmpP GGY+p++ykr++p +++++ + l+++  ++ +g+y+++ + +e ++   ek  +r+ ++Pll+Ae+dr  +++  + +  e++l+
  EEA19005.1  2 SQDMPPVGGYRPVQYKRNIPARGFKPFTYLVGMHLIMGYGFYKYYYGVRELNELAREKMWSRIHLIPLLQAEEDRDQVRRHFADQAREKELL 93
                7******************************************************************************9999999999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (119 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       391  (0.0218082); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.29s 00:00:00.69 Elapsed: 00:00:00.44
# Mc/sec: 805.75
//
Query:       EEA19006.1  [L=401]
Description: tRNA m(1)G methyltransferase domain containing protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.7e-23   81.9   0.0    5.5e-22   78.4   0.0    2.3  1  tRNA_m1G_MT  tRNA (Guanine-1)-methyltransferase
  ------ inclusion threshold ------
        0.2   12.1   0.5       0.54   10.7   0.5    1.7  1  DUF5598      Domain of unknown function (DUF5598)
        1.4    7.5   5.0        1.9    7.1   5.0    1.1  1  Ndc1_Nup     Nucleoporin protein Ndc1-Nup
        4.5    6.1  14.2         14    4.5  11.5    2.3  2  NARP1        NMDA receptor-regulated protein 1


Domain annotation for each model (and alignments):
>> tRNA_m1G_MT  tRNA (Guanine-1)-methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.4   0.0   1.2e-25   5.5e-22       2     195 .]     158     351 ..     157     351 .. 0.88

  Alignments for each domain:
  == domain 1  score: 78.4 bits;  conditional E-value: 1.2e-25
                  GGSHHHHHHHHHHHHHHHHHHHHCSSCEEEEEEETSSHHHHHHHHHHHCCGHHCGG-TTEEEESSCGGHHHHCCCHHHCGG................. CS
  tRNA_m1G_MT   2 kkasekelvslevqllrdytanrrntvddelygggagmvlkaepelealesvntekwkvilltptGkkftqelaeeLseke................. 82 
                   ++ ++++ sl +q++r+y++n ++    +l+   +++ lk + +++ ++    e+w+ i + p++     e+a e    +                 
   EEA19006.1 158 HLMDDRQRISLGSQITRAYSDNSKAAYRSHLIISSFDKLLKERFDTVLRKMH--ENWRGIRFMPEDFVHAAEQAKE----Nmkgphggnlagafadke 249
                  6799****************************************99999975..4888888888844433333333....233446777777777777 PP

                  .......GEEEEETTTSSBECCGGTTSSEEEEEESSSSTTCSTTHHHHHHHHHHHHTTTC.EEB-S-CCC...CHCTS..CTTSEHHTEHHHHHHHHH CS
  tRNA_m1G_MT  83 .......klvylcgdyegvdervdddkvdeysIGdfVlkggekgalvlidavkrllaGvlntaslpedsfsnrllekpnytrpltlrglkVpeiLlsg 173
                         ++vyl+ d++++++++++    +y+IG++V+k++ kg+    + +k+ ++G + ta+lp+ ++   l +++  + +l+++  +V+ei+  +
   EEA19006.1 250 gfapengEVVYLSSDSPNTLTELKPYS--TYIIGGLVDKNKHKGV----CYQKAIEKGMK-TAKLPIGEY---LRMAS--RPVLATN--HVAEIMMRW 333
                  999999*********************..****************....***********.*********...99988..899****..********* PP

                  CCCTTTHHHHHHHHHHHSCSXS CS
  tRNA_m1G_MT 174 nhakienWrlkealertvprRk 195
                   +   ++W   ea++r++p+Rk
   EEA19006.1 334 LE--LGDW--GEAFLRVIPQRK 351
                  **..****..***********7 PP

>> DUF5598  Domain of unknown function (DUF5598)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.5   0.00012      0.54      50      95 ..      93     138 ..      87     140 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00012
     DUF5598  50 eylegqvvteekveeakevvkehfkkevfnekgwekildkhdGkLP 95 
                 ++l++q   e+k e++k+  ++  ++++ ++++w++i+++ +G++P
  EEA19006.1  93 RMLRQQKWDEQKEERKKQRKEKNKQRKIRKREEWQHIVEENGGNIP 138
                 56677777788888888888888889******************99 PP

>> Ndc1_Nup  Nucleoporin protein Ndc1-Nup
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   5.0   0.00042       1.9     367     495 ..      18     204 ..       2     219 .. 0.42

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.00042
    Ndc1_Nup 367 knkasapvkelprlsksplkkkddeifgn.......sltaeaspkssssskegvekalsslakspgqspsptarls.prarkllekaksrllskeqkea 457
                 +++++++ + +p +s   lk+ d++ + +       +   ++++   +++++++e+++ ++++ ++  + p   ls +++++ l+++k + +++e+k++
  EEA19006.1  18 TTESTTTDNGEPVMS-GTLKSGDEPAIETsdentklA---TTTANTLQNQTNETEEKQEEATEGNV--TAPGVPLSkRQQKRMLRQQKWDEQKEERKKQ 110
                 222222222222222.222222222111123222121...12222222444555554444444444..3444444445555555555555455444444 PP

    Ndc1_Nup 458 lsestikkk................................................vekelaqllksp..................ligylFrqslrr 490
                  +e++ + k                                                +                             li+  F++ l+ 
  EEA19006.1 111 RKEKNKQRKirkreewqhiveenggnippkkrsvlvpvtlvidcgwdhlmddrqrisL----------GsqitraysdnskaayrshLIISSFDKLLKE 199
                 4444444444544555555555555555555555555555544444444444444431..........0333333333334445555666666666666 PP

    Ndc1_Nup 491 rleal 495
                 r + +
  EEA19006.1 200 RFDTV 204
                 66555 PP

>> NARP1  NMDA receptor-regulated protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5  11.5    0.0031        14     385     443 ..      59     124 ..       3     142 .. 0.78
   2 ?    1.8   0.0     0.019        87     374     449 ..     303     379 ..     297     400 .. 0.57

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.0031
                 HHHH-TTGGG---HHHHHT.......-S-HHHHHHHHHHHHHHHHHHHHHHHHHHHHH--...... CS
       NARP1 385 kledkpkakeeekeeaksa.......elseaerkklrkkakkaekkaekeeaekaekekekkaaek 443
                 +l+++ +++ee++eea+++        ls++++k++ +++k +e+k+e+++++k++++++k ++++
  EEA19006.1  59 TLQNQTNETEEKQEEATEGnvtapgvPLSKRQQKRMLRQQKWDEQKEERKKQRKEKNKQRKIRKRE 124
                 555666666666665555555567778999999999999999999999988887776666544333 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.019
                 HHHHHHHHHHHHHHH-TTGGG---HHHHHT..-S-HHHHHHHHH.HHHHH.HHHHHHHHHHHHHHH--.......----- CS
       NARP1 374 kaakgaievYlkledkpkakeeekeeaksa..elseaerkklrk.kakka.ekkaekeeaekaekekekkaaekkakked 449
                 k ak  i  Yl+++ +p +++++  e+++   el +  +  lr   ++k  +k+ + ++ae  e+e+e+++a    +++d
  EEA19006.1 303 KTAKLPIGEYLRMASRPVLATNHVAEIMMRwlELGDWGEAFLRViPQRKGaQKRDRSDHAEDVEDEDESETA---GDNAD 379
                 789999999999999999999999999988443333333333334344442555555555544544443322...22222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (401 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2617  (0.145965); expected 358.6 (0.02)
Passed bias filter:                      821  (0.0457917); expected 358.6 (0.02)
Passed Vit filter:                       149  (0.00831056); expected 17.9 (0.001)
Passed Fwd filter:                        23  (0.00128284); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.82u 0.36s 00:00:01.18 Elapsed: 00:00:00.53
# Mc/sec: 2288.25
//
Query:       EEA19007.1  [L=720]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.9e-27   95.4   0.9    2.9e-27   95.4   0.9    1.6  2  Fungal_trans  Fungal specific transcription factor domain
    5.2e-08   32.9  10.6    5.2e-08   32.9  10.6    1.9  2  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.4   0.9   3.2e-31   2.9e-27       3     266 ..     189     441 ..     188     443 .. 0.83
   2 ?   -3.6   0.1      0.51   4.6e+03      95     123 ..     580     608 ..     550     609 .. 0.71

  Alignments for each domain:
  == domain 1  score: 95.4 bits;  conditional E-value: 3.2e-31
  Fungal_trans   3 rffsnfhpqfpilhkpsflpkt.....ssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwil 94 
                    +fsn+hpq+p+lh+p+f         +s +++++a +++ l+++ +    l++  + ++++++    +        + +  i +++ + ++ l ++
    EEA19007.1 189 AYFSNIHPQYPFLHQPTFRAMEqecleASLRNNINAASESSLFFVLMVRHFLSCFITPSKQTPQGYYAM--------ALNY-I-AHLLDMDN-LLSI 274
                   6*******************99*****777777777777777755555555555555555545555544........2222.2.24445555.**** PP

  Fungal_trans  95 qsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcdddd 191
                   q+ l++++y+  s+   + ++++g+a+r +++lg hr  +++ ++    ++  ++e+ +R++w a+ +D   +++lGrp  ++ds i+++LP d dd
    EEA19007.1 275 QAMLCCAVYSVRSQAGVSLWKISGMAMRHCVELGYHRSTERYRNS----VDTLTKEISKRCFWVAYDIDLVASFILGRPAGISDSAIDVELPLDIDD 367
                   *****************************************9975....99999**************************88**************5 PP

  Fungal_trans 192 lwesddaseetlvetklsneeksrkiasfllaLkkilskiagsllsiekqlqqrdlqseklswveeleraldnWr 266
                   + ++ d      ++++ s+++++   a+  ++L +++sk+  +l+s +++ ++ ++++ +   ve l+ +l++Wr
    EEA19007.1 368 EYITRDG-LLCPPRQNTSDPPTQLTGALHSIKLRQLWSKFRNNLFSTNSHQENDSSRNPNRIPVEVLRQELEEWR 441
                   5444443.3333333479***************************************99***************8 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 0.51
  Fungal_trans  95 qsLlllelyektssdralherhhgvavrl 123
                       ++e ++ ++s+r+ +e++++ ++++
    EEA19007.1 580 VLIIIAERWNEACSYRDIFELLSESTITM 608
                   44567888888999999999999999887 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.9  10.6   5.8e-12   5.2e-08       2      31 ..      25      54 ..      24      60 .. 0.93
   2 ?   -2.5   0.1      0.64   5.8e+03      24      34 ..     586     595 ..     586     597 .. 0.80

  Alignments for each domain:
  == domain 1  score: 32.9 bits;  conditional E-value: 5.8e-12
                S-HHHHHCT---STSSSS-HHHHHCTHHHC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCt 31
                aC+nC+++K KCd++ P+CsnC k+  +C 
  EEA19007.1 25 ACTNCKQRKLKCDGQSPKCSNCTKSDRDCL 54
                9****************************6 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.64
                 HHCTHHHCCCC CS
     Zn_clus  24 kklnleCtfys 34 
                 +++n  C+ y+
  EEA19007.1 586 ERWNEACS-YR 595
                 58999999.76 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (720 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       572  (0.0319036); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.71u 0.30s 00:00:01.01 Elapsed: 00:00:00.51
# Mc/sec: 4235.42
//
Query:       EEA19008.1  [L=289]
Description: aldolase, putative, partial [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.2e-46  159.1   0.0    1.4e-46  158.7   0.0    1.1  1  Aldolase_II  Class II Aldolase and Adducin N-terminal domain


Domain annotation for each model (and alignments):
>> Aldolase_II  Class II Aldolase and Adducin N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  158.7   0.0     8e-51   1.4e-46       2     186 .]      47     228 ..      46     228 .. 0.92

  Alignments for each domain:
  == domain 1  score: 158.7 bits;  conditional E-value: 8e-51
                  HHHHHHHHHHHTTSSCTTBCEEEEEET.STTEEEEEBTSS-GGGHTGGGEEEEETTSCEEEECECSSSTB-.TTHHHHHHHHHH-TT-SEEEEE--HH CS
  Aldolase_II   2 elaeasrllarrglvegtgGniSvrvp.eedsflitpsgvdfeeltaedlvvvdldsgevvegkekggkps.setplHlaiykarpdaravvHtHspa 97 
                  ++a a+r++a++g+++g +G+iS+r+p ++++f+i+p+gv+f+ lt +d+v +d + g+++ g  ++++++ +++ +H+ai++arpd +a +H+Hsp+
   EEA19008.1  47 QMAGAFRIFAKLGFADGASGHISLRDPvQPETFWINPYGVHFGVLTVADMVHIDRE-GNRIGG--GDAAVNrAGFIIHRAIHEARPDLHAACHMHSPY 141
                  899**********************9999*************************66.****55..6678999************************** PP

                  HHHHHTCCSTSCHCCSSHHHHC.HSSSEEEEES-SSTTCHHH....HHHHHHHHHHS-SEEEETTTEEEEEESSHHHHHHHHHHHHHHHHHHH CS
  Aldolase_II  98 avalsalagkeglppltqeaaklllgdevpvipyaapgteel....gealaealkedakavllrnHGlltvGetleeAvalaetleeaaeiql 186
                  + a+s++  ++g+++l+q++++++  +++ v+  +  g + l    g+++a+al+  +k ++l+nHG+lt+G t++eA+a +++le+a+++ql
   EEA19008.1 142 GRAWSTF--GRGIDMLNQDSCMFY--EDLSVYAGF--GGVVLapeeGDNIARALGPRNKNIILQNHGILTCGGTIAEAAAFFIALERACHTQL 228
                  *****65..8************77..889995555..545556999********966799******************************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (289 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       255  (0.0142228); expected 358.6 (0.02)
Passed bias filter:                      241  (0.0134419); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.48
# Mc/sec: 1822.89
//
Query:       EEA19009.1  [L=343]
Description: 2-hydroxyacid dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.7e-56  187.9   0.0    1.5e-55  187.4   0.0    1.3  1  2-Hacid_dh_C   D-isomer specific 2-hydroxyacid dehydrogenase,
    1.3e-17   63.7   0.0    1.7e-17   63.3   0.0    1.1  1  2-Hacid_dh     D-isomer specific 2-hydroxyacid dehydrogenase,
    1.4e-07   31.8   0.0      4e-07   30.3   0.0    1.8  2  NAD_binding_2  NAD binding domain of 6-phosphogluconate dehyd
  ------ inclusion threshold ------
      0.017   14.7   0.0      0.039   13.5   0.0    1.6  2  IlvN           Acetohydroxy acid isomeroreductase, NADPH-bind
      0.019   15.6   0.0      0.038   14.6   0.0    1.6  1  F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
       0.18   11.4   0.0       0.57    9.8   0.0    1.8  2  ApbA           Ketopantoate reductase PanE/ApbA


Domain annotation for each model (and alignments):
>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  187.4   0.0   4.9e-59   1.5e-55       2     178 .]     128     305 ..     127     305 .. 0.96

  Alignments for each domain:
  == domain 1  score: 187.4 bits;  conditional E-value: 4.9e-59
                   HHHHHHHTTHHHHHHHHHTTCC.HTTCCGSBS-GTTSEEEEES-SHHHHHHHHHHHHTT-EEEEESSSHHHHHCHHHHTCEEC.SHHHHHHH-SEEE CS
  2-Hacid_dh_C   2 alllallrrlaeadeevregew.ksekallgkelsgktvGiiGlGrIGqavakrlkafgmkviaydrskkkeeeeeelgvelv.sleellaesDivs 96 
                    l la+lr++++a+++ r+g w +    ++g++  g t+Gi+G+G+IG+ +ak++ af+mk+++y+r++ + eee++++++++ +l+ell e+D+vs
    EEA19009.1 128 FLTLAVLRNTTNAEKSARNGSWrSGAGLVPGRDPGGLTLGIVGMGAIGKYMAKKALAFNMKITYYNRRQLPAEEEAKYNATYCsTLHELLGEADVVS 224
                   5899******************77777899******************************************9999999976669************ PP

                   E-S--STTTTTSBSHHHHHCSTTTEEEEESS-GGGB-HHHHHHHHHTTSCCEEEES--SSSSSGTCHHHHHSTTEEE-SS-T CS
  2-Hacid_dh_C  97 lhlpltpetrhlinaeelakmkkgailiNtaRGglvdeeaLleaLksgkiagaalDvfeeeplpedspllelpnviltPHia 178
                   l++pl++et++li+a+e+a+mk+g++l+NtaRG++++e  L+eaL+sgk+a a+lDvf++ep p+   +l+ ++v++ PH++
    EEA19009.1 225 LNCPLNNETTNLIGAAEFAAMKDGVFLVNTARGPVIHEPSLIEALESGKVARAGLDVFANEPSPDP-YFLKSDKVVVQPHLG 305
                   ****************************************************************55.89***********97 PP

>> 2-Hacid_dh  D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.3   0.0   5.6e-21   1.7e-17      28     133 ..      44     336 ..      18     337 .. 0.94

  Alignments for each domain:
  == domain 1  score: 63.3 bits;  conditional E-value: 5.6e-21
                 SSHHHCHHHHTT...ESEEEE-TTS....-BSHHHHHHH.TT--EEEESSSSCTTB-HHHHHHTT-EEEE-TTTTHHHHHHHH................ CS
                 xxxxxxxxxxxx...xxxxxxxxxx....xxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................ RF
  2-Hacid_dh  28 llteellekakd...adalivrsnt....kvtaevleal.pkLkviaragvGvDnvDldaakerGilVtnvpgystesvAElt................ 102
                  +++ + e++k+   +da i+r  t    ++++++l+ l p++k+i  a++G++ +D+d+++ + i+ +n+ ++ +e++A+++                
  EEA19009.1  44 ETQQMIPEDIKKngpIDAFIIRMGTppyePFDEDLLKDLvPGCKIITSASAGFNEFDVDWMASKDIWFCNTVNAVAEATADMAifltlavlrnttnaek 142
                 3444444555556679********99999********************************************************************** PP

                 ................................................................................................... CS
                 ................................................................................................... RF
  2-Hacid_dh 103 ................................................................................................... 102
                                                                                                                    
  EEA19009.1 143 sarngswrsgaglvpgrdpggltlgivgmgaigkymakkalafnmkityynrrqlpaeeeakynatycstlhellgeadvvslncplnnettnligaae 241
                 *************************************************************************************************** PP

                 ................................................................T-BHHHHHHHHHHHHHHHHHHHTTCCGTTBC CS
                 ................................................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  2-Hacid_dh 103 ................................................................aaTeeaqeniaeeaaenlvaflkgespanav 133
                                                                                 ++T+ a  ++ +e++en++a ++ ++p+++v
  EEA19009.1 242 faamkdgvflvntargpvihepsliealesgkvaragldvfanepspdpyflksdkvvvqphlgGLTDVAFMKAERECFENIRALFTKGKPNSPV 336
                 ********************************************************************************************998 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       1.7     5e+03      62      92 ..      38      69 ..      19      73 .. 0.73
   2 !   30.3   0.0   1.4e-10     4e-07       2      87 ..     166     252 ..     165     275 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 1.7
                   -SSSHHHHHHHHHS.HCCC--TT-EEEE-S-- CS
  NAD_binding_2 62 mvkagkavdevieg.llealkkgdilidgsts 92
                     ++ ++++++i + ++++   ++++i ++t 
     EEA19009.1 38 PATNRAETQQMIPEdIKKNGPIDAFIIRMGTP 69
                   45667778888887788888889999999985 PP

  == domain 2  score: 30.3 bits;  conditional E-value: 1.4e-10
                    EEEE--SHHHHHHHHHHHHTT-EEEEE-SSHHHHHHHHHTTEEE-SSHHHHHHHCSEEEE-SSSHHHHHHHHHS.HCCC--TT-EEE CS
  NAD_binding_2   2 igfiGlGvMGsnmalnllkagykvavynrtkekveelvaegakaaesieelvasldvvitmvkagkavdevieg.llealkkgdili 87 
                    +g++G+G +G+ ma++ l+ ++k++ ynr++  +ee ++ +a+ ++++ el+ ++dvv +  + ++++ ++i    ++a+k g +l+
     EEA19009.1 166 LGIVGMGAIGKYMAKKALAFNMKITYYNRRQLPAEEEAKYNATYCSTLHELLGEADVVSLNCPLNNETTNLIGAaEFAAMKDGVFLV 252
                    79**********************************************************999999999998875456666666665 PP

>> IlvN  Acetohydroxy acid isomeroreductase, NADPH-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0       2.2   6.5e+03     112     142 ..      12      42 ..       6      48 .. 0.76
   2 ?   13.5   0.0   1.3e-05     0.039       6      72 ..     165     231 ..     162     270 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 2.2
                 EEEEEESS-SHHHHHHHHTT----EEEEEEE CS
        IlvN 112 vvlvAPkgpGhlvreeyeegkGvpaliaveq 142
                 v+l  Pk +G+   e++++ + + +l a ++
  EEA19009.1  12 VCLGEPKFVGEDYLEKFQTEFRYSVLPATNR 42 
                 5666799999999999999888888777665 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 1.3e-05
                 -EEEES-SHHHHHHHHHHHHTT--EEEEE-TT-HHHHHHHHTT-EEEEHHHHHHT-SEEEE-S-HHH CS
        IlvN   6 kiaviGyGsqGhaqalnlrdsgldvvvglregsksvkkAkeegfevltvaeavkkadvvmiliPDel 72 
                 ++ ++G+G+ G+  a++     +++++ +r++    ++Ak ++    t++e+  +advv +  P + 
  EEA19009.1 165 TLGIVGMGAIGKYMAKKALAFNMKITYYNRRQLPAEEEAKYNATYCSTLHELLGEADVVSLNCPLNN 231
                 789*********************************************************9999543 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.0   1.3e-05     0.038       2      72 ..     166     230 ..     165     256 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 1.3e-05
                    EEEETTSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC-EEECECHHHHHHH-SEEEE-S-HH CS
  F420_oxidored   2 igiiGaGnmgealasgllaagaqpheivvansrnpekaeelaeelgvkvtavdneeaaeeadvvvlavkpe 72 
                    +gi+G+G +g+ +a+++la +    +i+   +r +  aee +++++++ ++ +  e++ eadvv l ++ +
     EEA19009.1 166 LGIVGMGAIGKYMAKKALAFN---MKITYY-NRRQLPAEE-EAKYNATYCS-TLHELLGEADVVSLNCPLN 230
                    89*******************...9**966.555555544.4677888999.999*********9999876 PP

>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0      0.76   2.3e+03      60      76 ..      45      66 ..      27      92 .. 0.66
   2 ?    9.8   0.0   0.00019      0.57       2      40 ..     167     204 ..     166     227 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.76
                CH.....SCCCCS-ESEEEE-S CS
        ApbA 60 ae.....ekselepidlvivtv 76
                ++     ++++++pid +i+ +
  EEA19009.1 45 TQqmipeDIKKNGPIDAFIIRM 66
                2245555688999999999865 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00019
                 EEES-SHHHHHHHHHHHHHTHCEEEE-SCH.HHHHHHHHC CS
        ApbA   2 ailGaGaiGsllaakLakagadvtlilrsr.rlealkknG 40 
                  i+G+GaiG ++a k  + + ++t ++r++  +e+  ++ 
  EEA19009.1 167 GIVGMGAIGKYMAKKALAFNMKITYYNRRQlPAEE--EAK 204
                 59************99999999******9955554..443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (343 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       300  (0.0167327); expected 358.6 (0.02)
Passed bias filter:                      290  (0.0161749); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.48u 0.23s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 2498.06
//
Query:       EEA19010.1  [L=481]
Description: sarcosine oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-31  110.6   0.0    1.4e-31  110.4   0.0    1.1  1  DAO            FAD dependent oxidoreductase
    1.6e-06   28.3   0.0    3.7e-06   27.1   0.0    1.6  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
    5.4e-05   22.6   0.0    0.00016   21.0   0.0    1.8  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
    0.00011   22.2   0.0       0.11   12.4   0.0    2.6  2  NAD_binding_9  FAD-NAD(P)-binding
    0.00025   20.3   0.0      0.017   14.2   0.0    2.3  2  FAD_binding_2  FAD binding domain
     0.0052   16.3   0.0      0.071   12.6   0.0    2.5  3  Glu_dehyd_C    Glucose dehydrogenase C-terminus
     0.0085   15.4   0.0       0.18   11.0   0.0    2.1  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
      0.013   14.2   0.0       0.18   10.5   0.0    2.1  2  HI0933_like    HI0933-like protein
      0.026   13.6   0.0        2.1    7.4   0.0    2.5  3  GIDA           Glucose inhibited division protein A
      0.047   12.9   0.0      0.077   12.2   0.0    1.2  1  FAD_binding_3  FAD binding domain
       0.08   13.2   0.0       0.17   12.1   0.0    1.6  1  TrkA_N         TrkA-N domain
      0.081   13.0   0.0       0.15   12.1   0.0    1.3  1  Shikimate_DH   Shikimate / quinate 5-dehydrogenase
       0.13   11.5   0.0       0.28   10.4   0.0    1.5  1  Thi4           Thi4 family


Domain annotation for each model (and alignments):
>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.4   0.0     1e-34   1.4e-31       2     351 ..      12     424 ..      11     425 .. 0.70

  Alignments for each domain:
  == domain 1  score: 110.4 bits;  conditional E-value: 1e-34
                 EEEECTSHHHHHHHHHHHHTT...EEEEESSSS.........TTSSGGGSSEEEEESSSSTHHSTHHHHHHHHHHHHHHHHHHHH....HSS....... CS
         DAO   2 vviiGGGiiGlstAyeLarrg...Vtllekgdi.........agsgaSgrnsgllhsglrylpeaselarlslealeelreleee....lgi....... 77 
                 ++i+G+G +GlstA++L rrg   Vt+++k++           + +aS    +++++ +   ++   + + +lea+e + ++++e    + +       
  EEA19010.1  12 IIIVGAGAFGLSTALHLGRRGytdVTVFDKQPYdeslysyfnGCDAASADINKIIRAVY--GKDV-IYQDITLEAVEGWNQWNAElqsgQTVppgmtts 107
                 89*****************************778899888763349999999*****65..3332.333777777777766666533222222333333 PP

                 TTSEEEEEEEEEESS.......HHHHHHHHHHHHHHHHTTTTEEEEEHHHHHHHSTT.ST...TTSEEEEETTEEEEEHHHHHHHHHHHHHHTT-EEEE CS
         DAO  78 didyrrtGllslaad.......eeelealdkllallleagldaelldaeevrelepa.lp...gllgalfypdtgqvdpakltaalaraaealGveile 165
                 d  + ++G+l+++++       +++le + k+ +l++ +  d el ++   + lep   +   +   +lf++++g   + k++++ +++a++ G+++++
  EEA19010.1 108 DRVWVNNGHLVMTDGpvlppfeQASLESMPKNTQLVTTNAQDQELAKS-VGLNLEPFkRQnpsRPNVGLFDRTGGMTYADKACRFALHKARSYGAKFVL 205
                 677777777777643333322234455555555555333333333222.1223444431133444678******************************* PP

                 SECEEE.EEE..EE..TCEEEEEEECT.EEEEEEEEEEE--GGGHH.HHHTTCTTTSEEEEEEEEEEEEEECCTHSTGSGCSEEEEE.......EEETT CS
         DAO 166 gtevtg.lee..ed..gkvwgverttp.gendaadavVnaaGawsd.llgllkeldlpispvrgqvlvlkplseklvspaailpvpe.......tdddg 250
                   +v g l+e  ++  gkv+g+ r t+ g +++a  v++a+G w+  +l   + ld   +++ g+v  l ++++     ++ +p  +       +d  +
  EEA19010.1 206 D-PVAGeLKEllRGdkGKVTGI-R-TAdGKTHHASVVILACGGWTPsIL---PALDGLNEATAGSVALL-KIPKDSPLYDQFAPKNFpswmhkmRDGHS 297
                 *.9999676566225699****.5.55598877799**********777...666644599*****999.5544222222444444477999999999* PP

                 TTEEEEEE.TTSEEEEEESSE....................EETTCSS....TSCSHHHHHHHHHHHHHHSGGG....CGEEEEEEEEEE.ETTSSEEE CS
         DAO 251 rgvyvtpr.kdgrvlvGgtad....................eesgddd....pevdeedidellealrklfPql....gdvlrkwaGlrp.lpdglpli 319
                 +g+y +pr  dg +++G  ++                    ++          +++ +++  +   l +++P+l     +++ ++ + +    d+   +
  EEA19010.1 298 GGLYGFPRtDDGWLKIGYRGTkytnpqvqsdgrersvpitrWT----KeesiKAIPKQALSVIQTFLDEYLPELgeagIHISMTRICWYNdSFDNHLTV 392
                 *******945667999999877788888777776666554322....222235666668888***********84444447777777666458999999 PP

                 EEEETEEEEEEEEECTTTHHHHHHHHHHHHHH CS
         DAO 320 getpgvkglylatGhsghGltlapatGkllae 351
                 +++pg +gl +at  sgh+++  p  G ++++
  EEA19010.1 393 DRVPGMDGLMVATSGSGHAFKYLPSLGNWIVD 424
                 **999************************987 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.1   0.0   2.7e-09   3.7e-06       1      29 [.      14      43 ..      14      44 .. 0.96

  Alignments for each domain:
  == domain 1  score: 27.1 bits;  conditional E-value: 2.7e-09
                   EE--SHHHHHHHHHHHCCTE.EEEEE-SSS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagf.dvlllekrd 29
                   IvGaG++Gl++A +L ++g+ dv++++k++
     EEA19010.1 14 IVGAGAFGLSTALHLGRRGYtDVTVFDKQP 43
                   9*******************89******97 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0   0.0   1.2e-07   0.00016       1      40 [.      13      52 ..      13      64 .. 0.94
   2 ?   -2.7   0.0         2   2.8e+03     119     136 ..     230     247 ..     220     260 .. 0.63

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 1.2e-07
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEkgnignsiyryp 40
                 iI+GaG+ Gl++a++l + g +d+++ +k+   +s+y y 
   EEA19010.1 13 IIVGAGAFGLSTALHLGRRGYTDVTVFDKQPYDESLYSYF 52
                 8*************************************96 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 2
  Pyr_redox_3 119 sketyeAkkviiAtGefd 136
                  + +t +A+ vi+A G + 
   EEA19010.1 230 DGKTHHASVVILACGGWT 247
                  334667777777777654 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.4   0.0   8.2e-05      0.11       2      37 ..      14      45 ..      13      55 .. 0.87
   2 !    6.9   0.0    0.0041       5.6     119     154 ..     207     244 ..     183     245 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 8.2e-05
  NAD_binding_9  2 ivGaGprGlavlerLlarakkkspleitlfdpsepg 37
                   ivGaG+ Gl+++ +L +r      +++t+fd++++ 
     EEA19010.1 14 IVGAGAFGLSTALHLGRR----GYTDVTVFDKQPYD 45
                   9*****************....599******99875 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0041
  NAD_binding_9 119 vhraevvdleeradgq..avlladgaslaadaVvLAlG 154
                     + +e  +l + ++g    +++adg++++a  V+LA+G
     EEA19010.1 207 PVAGELKELLRGDKGKvtGIRTADGKTHHASVVILACG 244
                    555666666666666333699****************9 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.0   1.2e-05     0.017       2      33 ..      12      44 ..      11      59 .. 0.92
   2 ?    3.8   0.0     0.018        25     164     204 ..     212     248 ..     142     266 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 1.2e-05
                   EEEE--SHHHHHHHHHHHHTTT.-EEEEESSSG CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGl.kvavvekeqe 33
                   +i++G+G+ GL+ Al + ++G  +v+v +k ++
     EEA19010.1 12 IIIVGAGAFGLSTALHLGRRGYtDVTVFDKQPY 44
                   79****************************997 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.018
                    EEEEEE.CTTEEEEEEEEETTTTCEEEEEESEEEE-----GG CS
  FAD_binding_2 164 adeLiv.edgrvtGavvenpesgrevrirakavvlatgGfgr 204
                    ++eL++ ++g+vtG+  +   +g+++  +a  v+la+gG+  
     EEA19010.1 212 LKELLRgDKGKVTGIRTA---DGKTH--HASVVILACGGWTP 248
                    3456664466****9888...66655..699********974 PP

>> Glu_dehyd_C  Glucose dehydrogenase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.0   5.1e-05     0.071      32      71 ..      10      47 ..       2     118 .. 0.81
   2 ?   -1.2   0.0      0.83   1.1e+03     100     136 ..     236     274 ..     222     278 .. 0.78
   3 ?   -0.5   0.0      0.54   7.4e+02      90     136 ..     391     433 ..     381     442 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 5.1e-05
  Glu_dehyd_C 32 esalvlGaGslGLLalalleaeerglervyvlgrrdrpdp 71
                 +  +++GaG+ GL ++ +l   +rg+++v+v++++++++ 
   EEA19010.1 10 DPIIIVGAGAFGLSTALHLG--RRGYTDVTVFDKQPYDES 47
                 5679***********77776..69**********998875 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.83
  Glu_dehyd_C 100 emdlvvEaTGsakhafeaieal..apnGvaaLlGvpeds 136
                     +++ + G ++ ++ a++ l  a++G +aLl +p+ds
   EEA19010.1 236 ASVVILACGGWTPSILPALDGLneATAGSVALLKIPKDS 274
                  444677889999999999998854678999999999886 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 0.54
  Glu_dehyd_C  90 pvdeipeaseemdlvvEaTGsakhafeaiealapnGvaaLlGvpeds 136
                  +vd++p     md ++ aT  + haf+ +  l+   v a+ Gv +d+
   EEA19010.1 391 TVDRVP----GMDGLMVATSGSGHAFKYLPSLGNWIVDAMEGVGSDR 433
                  455554....799999999999************9999999998876 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.0   0.00013      0.18       3      30 ..      12      40 ..       4      87 .. 0.75
   2 ?    2.1   0.0     0.065        90      82     124 ..     220     262 ..     167     274 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00013
                 EEEE--SHHHHHHHHHHHHH.TS-EEEEE CS
                 xxxxxxxxxxxxxxxxxxxx.xxxxxxxx RF
  Pyr_redox_2  3 vvviGgGpAGlaaaltlaqa.gakvtlve 30
                 ++++G+G+ Gl++al+l++    +vt+++
   EEA19010.1 12 IIIVGAGAFGLSTALHLGRRgYTDVTVFD 40
                 67777777777777777774144666663 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.065
                  CEEEEETEEECTCEEEEEESEEEE---E.EE-BC.TCTTC.TTBE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxx.xxxxxxxxxx RF
  Pyr_redox_2  82 kkkvklekkkegdeekiaydklvlAtGs.sprdl.gipGvaenvg 124
                  k+kv+   +   d+++  +  ++lA G+ +p +l  ++G++e + 
   EEA19010.1 220 KGKVTGIRT--ADGKTHHASVVILACGGwTPSILpALDGLNEATA 262
                  345555433..5677899999999999844444458888866654 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00013      0.18       3      32 ..      12      42 ..      10      44 .. 0.88
   2 ?    1.3   0.0     0.082   1.1e+02     138     165 ..     219     246 ..     189     253 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00013
                 EEEE--SHHHHHHHHHHHHTT-.-EEEE-SS CS
  HI0933_like  3 viviGgGaAGlmaAisaakrgk.rVllleka 32
                 +i++G+Ga Gl +A+++++rg  +V++++k+
   EEA19010.1 12 IIIVGAGAFGLSTALHLGRRGYtDVTVFDKQ 42
                 89***************9988537*****97 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.082
                  ETTE.EEEEE.TTEEEEESEEEE----S CS
  HI0933_like 138 eedgkfrvktkseeeleadklvlAtGGl 165
                  +++++  ++t ++++ +a+ ++lA+GG 
   EEA19010.1 219 DKGKVTGIRTADGKTHHASVVILACGGW 246
                  566778899999**************95 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.0     0.021        29       2      24 ..      12      34 ..      11      72 .. 0.87
   2 ?   -2.9   0.0       1.9   2.6e+03     129     166 ..     102     139 ..      76     165 .. 0.65
   3 ?    7.4   0.0    0.0015       2.1     118     151 ..     212     246 ..     205     266 .. 0.81

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.021
                EEEE-SSHHHHHHHHHHHHTT-- CS
        GIDA  2 viViGgGhAGceAAlaaarlGak 24
                +i++G+G  G+  Al++ r+G+ 
  EEA19010.1 12 IIIVGAGAFGLSTALHLGRRGYT 34
                89******************974 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.9
                 EEEEETTS-EEEECEEEE--TT-BT-EEEETTEEEESS CS
        GIDA 129 kgvvtedgetikakavviatGtflkgkihigekelsaG 166
                  g++t+d   +++ + v++ G+ l    +   +++++ 
  EEA19010.1 102 PGMTTSDRVWVNNGHLVMTDGPVLPPFEQASLESMPKN 139
                 47888889999999999999995444444444444443 PP

  == domain 3  score: 7.4 bits;  conditional E-value: 0.0015
                 EEEEEECT.TEEEEEEETTS-EEEECEEEE--TT- CS
        GIDA 118 veelivee.kkvkgvvtedgetikakavviatGtf 151
                  +el+  + +kv+g++t+dg+t +a++v++a G +
  EEA19010.1 212 LKELLRGDkGKVTGIRTADGKTHHASVVILACGGW 246
                 5555443349***********************74 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   5.6e-05     0.077       4      33 ..      12      42 ..      10      48 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 5.6e-05
                   EEEE--SHHHHHHHHHHHHTTHH.EEEEESS CS
  FAD_binding_3  4 VlIVGaGpaGlmlallLseaGvr.vvlvekr 33
                   ++IVGaG  Gl++al L ++G   v++ +k+
     EEA19010.1 12 IIIVGAGAFGLSTALHLGRRGYTdVTVFDKQ 42
                   79*******************7547787776 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   0.00012      0.17       1      31 [.      12      43 ..      12      63 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00012
                EEEES-SHHHHHHHHHHHH.TTEEEEEEESSH CS
      TrkA_N  1 iiiiGlGrvGrslaeeLse.ggkdvvvidkde 31
                iii+G+G +G s a  L + g+ dv+v dk++
  EEA19010.1 12 IIIVGAGAFGLSTALHLGRrGYTDVTVFDKQP 43
                8******************77899*****988 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   0.00011      0.15      12      78 ..       9      74 ..       3      81 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00011
                  T-EEEEES-SHHHHHHHHHHHCCT-CEEEEEESSHHHHHHHHHHHT.ET-EEEEGCGHHHHHHT-SE CS
  Shikimate_DH 12 ekkvlliGaGemaelvakhLlakgvkkvvvaNRtlerakelaeelkgeeiealkleelkellaeadv 78
                  +  ++++GaG  +  +a hL ++g+++v+v+  +    ++l + ++g ++   +++++ +++   dv
    EEA19010.1  9 NDPIIIVGAGAFGLSTALHLGRRGYTDVTVFDKQPY-DESLYSYFNGCDAASADINKIIRAVYGKDV 74
                  56799*************************997653.455666666666666666666666655555 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0    0.0002      0.28      20      48 ..      12      40 ..       7      43 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.0002
                EEEE--SHHHHHHHHHHHHCTTS-EEEEE CS
        Thi4 20 vvivGaGssGLtaayylakkpdlkvaile 48
                ++ivGaG+ GL++a  l+++    v++++
  EEA19010.1 12 IIIVGAGAFGLSTALHLGRRGYTDVTVFD 40
                9******************9777777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (481 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       407  (0.0227007); expected 358.6 (0.02)
Passed bias filter:                      395  (0.0220313); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.44
# Mc/sec: 3255.04
//
Query:       EEA19011.1  [L=539]
Description: sugar transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-77  261.6  25.5    1.5e-77  261.4  25.5    1.0  1  Sugar_tr  Sugar (and other) transporter
    3.8e-21   75.4  44.3    2.3e-17   63.0  23.7    2.1  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  261.4  25.5   1.7e-81   1.5e-77       3     452 .]      33     499 ..      31     499 .. 0.95

  Alignments for each domain:
  == domain 1  score: 261.4 bits;  conditional E-value: 1.7e-81
                 HHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS CS
    Sugar_tr   3 lvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgkns 101
                  + al+g+   +d g  +++ +l++fak+fg ++++++      +++ +vs++++G+ +G+ ++ ++ dr+GR +sl   +v+ +ig+++ + ++   +
  EEA19011.1  33 ALYALAGIPLCWDQGSSATIPSLPGFAKEFGITSATNPS-----QVSNFVSLVYIGCGVGAALSFFVNDRVGRLWSLRLYSVIWIIGQLIAVGSQ--GN 124
                 5678999999************************99866.....57*************************************************..67 PP

                 -TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHH.HTSS-.TTHHHHHHHCCHHHHHHHHHHGGGS---HHHH CS
    Sugar_tr 102 vevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglgl.nktsn.adgwrillglqlvpallllilllflPESPryl 198
                 + v+++gR+++G+g+G  +v+ P+ + EiAp ++Rg l++++ + + +  ++aa++ +g    + + + +w++++++  ++  +++++ +f+ ESPr+l
  EEA19011.1 125 MKVMYAGRIVAGFGIGPLTVIGPVSLVEIAPSEIRGLLTTWFSVVLLMSLFMAAFTVYGCfVSMAAsSLQWQVPFFVPTIIMAFVILASFFVSESPRWL 223
                 ***********************************************************964444469******************************* PP

                 HHTT-HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH....................HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHH CS
    Sugar_tr 199 vekgkeeeakevlaklrgeedadrelaeekdsleaeqeee...............kaswkellssktvrqrlligvvlqifqqltGinaimyysptife 282
                 + kg++eea e l k+rg ++++++++ e + ++++  +e                a +ke +    +++r+  ++   ++ ql+G n+i+ y   i++
  EEA19011.1 224 FLKGRDEEAIEALVKIRGLPLDHPRVQSELQDIQKSLAKEraaygdatsyslrglGAILKETFLVPANLRRTQQAFISYALAQLSGANSITTYLVPILS 322
                 *******************9999888888888888877778888***999998888888888888889******************************* PP

                 HSS-THH....HHHHHHHHHHHHHHHHHH.HHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS.....CHHHHHHHHHHHHHHHTTTTHHHHHH CS
    Sugar_tr 283 nlglsks....llvtiivgvvnfvatfva.iflvdrfGRRtllllGaagmaicfvilgivalllvaks..kaasivaivfialfialfalgwgpvpwvl 374
                  +g++      ll+ +++gvv+f+ t++a +f+vd +GRR+ l+lG++++++  +++g  + + +a+   ++a+ +a+++i++  + +a+g+  +p+v 
  EEA19011.1 323 LVGVKGGtsysLLIAAMYGVVKFFYTVIAsFFFVDAIGRRNSLFLGITIQMLSDIYIGVYVKFKQAGPvpTSAGQAALAAIFIHGFGYAVGLLVLPYVF 421
                 ****9988899******************88***************************666666777799***************************** PP

                 HHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 375 vsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 vsEl p+++Rs+++a++ + +wl+ f ++  +p ++++ ++++ f++fag + l++i+ f+ vpet+g++le++++lf
  EEA19011.1 422 VSELWPNQIRSFGAALTQTFHWLFFFGVNKGIPSLLSSTNNWGAFIFFAGWCFLALIYSFLVVPETAGVDLEKLDALF 499
                 **************************************************************************9987 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.0  23.7   2.5e-21   2.3e-17      12     263 ..      48     350 ..      35     356 .. 0.78
   2 !   15.9  19.5   5.1e-07    0.0046      33     184 ..     331     494 ..     328     518 .. 0.81

  Alignments for each domain:
  == domain 1  score: 63.0 bits;  conditional E-value: 2.5e-21
       MFS_1  12 rsilgpalplalaedlg....ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa..sslwlllvlrvlqGlgagalfp 104
                 +s+++p+lp   a+++g     +ps+++  ++l+++g++v++ +  ++ dr+Gr + l l  +++++g l+++ +   ++ +++++r+++G+g g l+ 
  EEA19011.1  48 SSATIPSLP-GFAKEFGitsaTNPSQVSNFVSLVYIGCGVGAALSFFVNDRVGRLWSLRLYSVIWIIGQLIAV-GsqGNMKVMYAGRIVAGFGIGPLTV 144
                 677899999.9******888888999******************************************66666.4545566****************** PP

       MFS_1 105 agaaliadwfpkeergraigllsa.....gfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 +g + +++++p e rg+ + ++s+      f +++ +   + ++ assl W+++f++ +i+++++++   + +++++++r+ + + ++e          
  EEA19011.1 145 IGPVSLVEIAPSEIRGLLTTWFSVvllmsLFMAAFTVYGCFVSMAASSLQWQVPFFVPTIIMAFVIL---ASFFVSESPRWLFLKGRDEeaiealvkir 240
                 *******************9999966665666666777777778888999***************99...89999999999999999999********* PP

       MFS_1 189 ...................................kgtgpaplvpawkallkdpvl....w......illialllfffgfsglltllplylqevlgls. 241
                                                              +++a+lk  +l    +      ++ +al+  + ++s++++l+p++  +  g + 
  EEA19011.1 241 glpldhprvqselqdiqkslakeraaygdatsyslR---------GLGAILKETFLvpanLrrtqqaFISYALAQLSGANSITTYLVPIL--SLVGVKg 328
                 ********9999766666666655555444444440.........555555555443333133344448888888888999999999994..5555555 PP

       MFS_1 242 glllaglllallalvgailall 263
                 g  +++l+ a++++v ++  ++
  EEA19011.1 329 GTSYSLLIAAMYGVVKFFYTVI 350
                 3244444444444444333444 PP

  == domain 2  score: 15.9 bits;  conditional E-value: 5.1e-07
       MFS_1  33 eigl.lltlyalgaavaslpl.GrlsdrfGrrrvlllglllfalg.lllllf.....a....sslw.lllvlrvlqGlga.galfpagaaliadwfpke 117
                 +++l ++++y+++ ++ ++++  +++d +Grr  l+lg+++  l+ ++++++     a    +s   + l++ ++ G+g+  +l+ + ++++++++p +
  EEA19011.1 331 SYSLlIAAMYGVVKFFYTVIAsFFFVDAIGRRNSLFLGITIQMLSdIYIGVYvkfkqAgpvpTSAGqAALAAIFIHGFGYaVGLLVLPYVFVSELWPNQ 429
                 56662555599999888888844559*************************53446625667667778************667788889999******* PP

       MFS_1 118 ergraigllsagfslGa.ilgpllggllasslgWravfyilaivsllafvlfllllpeepperkrksp 184
                  r+++ +l +++  l +  +  ++ +ll+s  +W ++f+++a+ ++la++  + +l++++++    ++
  EEA19011.1 430 IRSFGAALTQTFHWLFFfGVNKGIPSLLSSTNNW-GAFIFFAGWCFLALI--YSFLVVPETAGVDLEK 494
                 ***********877777577799******9999*.9************55..6888888877666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (539 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       902  (0.0503096); expected 358.6 (0.02)
Passed bias filter:                      448  (0.0249875); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.68u 0.29s 00:00:00.97 Elapsed: 00:00:00.47
# Mc/sec: 3412.72
//
Query:       EEA19012.1  [L=262]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (262 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       330  (0.0184059); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.40
# Mc/sec: 1951.63
//
Query:       EEA19013.1  [L=494]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.8e-110  369.1   0.2   2.1e-110  368.9   0.2    1.0  1  DUF1338   Domain of unknown function (DUF1338)


Domain annotation for each model (and alignments):
>> DUF1338  Domain of unknown function (DUF1338)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  368.9   0.2  1.2e-114  2.1e-110       1     324 []      25     432 ..      25     432 .. 0.96

  Alignments for each domain:
  == domain 1  score: 368.9 bits;  conditional E-value: 1.2e-114
     DUF1338   1 elaralldalsekYlarvpkvralvelvraanaaslssegektdelerllvedHgAiRtggvtnegidalarlfaslGyvpvgeydlpekklpahwtaF 99 
                 el++a++ a+s++Y+++vp++++lv++v++ n++++++++++ d+l+rl++e+HgAiR+g  ++e++++++r+fa lG+++vg+ydl+ ++lp+h+t+F
  EEA19013.1  25 ELRTAFALAMSHMYKNEVPLYGDLVRIVQSRNHKVIANSSSTPDSLDRLTLERHGAIRLG--KPEELQTVSRIFALLGMHAVGYYDLSVAGLPMHATCF 121
                 6899***********************************9999*****************..************************************* PP

     DUF1338 100 rpp.eedlaknlpRvFiSeLrvedlsdaaqraieayvlaareiftkrllellekleed.ggltagdaeafvaealetfrwqkeapvakadyelLaaese 196
                 rp+ +++la n++RvF+++Lr++++ + a+++++ ++l++r+if+k+ll++l+ ++++ g+++ ++ae f++eal+tf+w + a +++++y+lL+ae++
  EEA19013.1 122 RPIdTASLATNPFRVFTTLLRPDLIRSPAAHDLALQLLERRNIFSKELLRMLDIATTQtGQFRVHQAEIFIREALRTFSWAPVAEATETEYQLLRAEHP 220
                 ***999************************************************9988789********************9999************** PP

     DUF1338 197 yaAwvl.vngyaiNHlTprvldidalqafleergiklkdeieGpptvspdglLrQtSfkAleeevkfa........egsgeev...........gavpa 275
                 ++A+++ +++++iNHlTpr+ldi+a+qa+++++g+++kd+ieGpp+++ ++lLrQtSf Alee+++f+        e     +           g+++a
  EEA19013.1 221 ILADIAsFRTAHINHLTPRTLDIEAAQAAMAAEGMPVKDRIEGPPRRKWPILLRQTSFLALEEKIQFKirdsdsesE-----EegdthnvelvdGSHKA 314
                 ********************************************************************998654441.....2356667899******* PP

     DUF1338 276 rfgEieqRgvlltnkgrnlydellkea....................................................................g.ep 305
                 rfgEie+Rg++ t++gr+lyd+ll+++                                                                    + +p
  EEA19013.1 315 RFGEIEERGAAVTPAGRALYDQLLESSmhmaedqretidealvssfraypdtweelrkqelvyvkygftaklpslsrydvvdsstiesliedgvlEtTP 413
                 ****************************************************************************************999876626** PP

     DUF1338 306 ilyedFlpgnAagIFestl 324
                 i+yedFlp++AagIF+s+l
  EEA19013.1 414 ITYEDFLPFSAAGIFQSNL 432
                 *****************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (494 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       438  (0.0244297); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.46
# Mc/sec: 3232.92
//
Query:       EEA19014.1  [L=788]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.9e-195  648.9   0.0   2.7e-195  648.4   0.0    1.2  1  VID27           VID27 C-terminal WD40-like domain
    4.7e-78  261.0   0.3    4.7e-78  261.0   0.3    3.4  4  VID27_N         VID27 N-terminal region
    1.1e-47  160.8   2.0    2.9e-47  159.5   0.8    2.1  2  VID27_PH        VID27 PH-like domain
     0.0033   17.8   6.4      0.013   15.8   3.8    2.2  2  UPF0149         Uncharacterised protein family (UPF0149)
  ------ inclusion threshold ------
       0.33   11.0   4.2        1.5    8.8   0.6    2.5  2  DUF3801         Protein of unknown function (DUF3801)


Domain annotation for each model (and alignments):
>> VID27  VID27 C-terminal WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  648.4   0.0  7.4e-199  2.7e-195       2     354 ..     415     767 ..     414     769 .. 0.99

  Alignments for each domain:
  == domain 1  score: 648.4 bits;  conditional E-value: 7.4e-199
       VID27   2 knsqlavgykndrsfvvrgdkiGvfkhtddnelefstaiskvetlkgkllsPkkvmlheedrklilqdekdknklykmDlerGkvvdewkvhddipvve 100
                 +nsqlavgyk+drsfvvrg+kiGvfkht++n+lefst+iskvet+ gkl+sPkkvmlh+ed+++ilqd  ++n+ly+mDle+Gkvvdewkvhddi v++
  EEA19014.1 415 VNSQLAVGYKHDRSFVVRGSKIGVFKHTPNNNLEFSTNISKVETPGGKLFSPKKVMLHAEDSNMILQDGANPNALYRMDLEYGKVVDEWKVHDDIGVTT 513
                 7************************************************************************************************** PP

       VID27 101 fapekkfaqlteeqtllGlsknalfriDPrlsgnklvdselkqyaskndfsavattekGyiavasekGdirlfdrlginaktalPalgdpiigldvsad 199
                 fape+kf+q+t+ q +lG+s+nalfr+DPr sgnklv+++lkqyaskndfsavattekGyiavas+kGd+rlfdrlginakt++Palg+piigldvsad
  EEA19014.1 514 FAPEQKFSQMTSAQPFLGVSNNALFRVDPRQSGNKLVEENLKQYASKNDFSAVATTEKGYIAVASNKGDVRLFDRLGINAKTHIPALGEPIIGLDVSAD 612
                 *************************************************************************************************** PP

       VID27 200 GrwvlatcktyllLiDalikegkneGklgfeksfakdskpkprrLklkpehvaqlqeetkkpvsftkakfntgldseettivtstGpfvitwslkkvlk 298
                 Grwvlatc+tyllLiDa++k+gkneGklgfeksfakdskp+prrL l+p+hvaq+q+etk+p+ ft+a+fntg+dseet+i+t+tGpf+itw+lkkvl+
  EEA19014.1 613 GRWVLATCRTYLLLIDAMQKDGKNEGKLGFEKSFAKDSKPQPRRLGLQPAHVAQFQHETKQPLAFTPARFNTGVDSEETSIITATGPFIITWNLKKVLA 711
                 *************************************************************************************************** PP

       VID27 299 gkkdpYkikryeeevvadnfkfgsdknvivalkndvsmvkkkslkkptreslatea 354
                 g+kdpY+ikry e+v+adnf+fgsdknvival+n+v+mv+kks+kkptres+a ++
  EEA19014.1 712 GRKDPYSIKRYGENVMADNFRFGSDKNVIVALPNEVNMVQKKSFKKPTRESIAGPM 767
                 ****************************************************9875 PP

>> VID27_N  VID27 N-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  261.0   0.3   1.3e-81   4.7e-78       1     173 []       1     173 [.       1     173 [. 0.99
   2 ?   -9.1  10.4         5   1.8e+04      76      89 ..     375     387 ..     326     392 .. 0.65
   3 ?   -9.6  14.1         5   1.8e+04      71      92 ..     377     401 ..     365     414 .. 0.51
   4 ?    0.5   0.0      0.13   4.7e+02     128     172 ..     512     557 ..     495     558 .. 0.82

  Alignments for each domain:
  == domain 1  score: 261.0 bits;  conditional E-value: 1.3e-81
     VID27_N   1 MfllkslgkllfgssskeelieipsGqLylvrpqspkgsselifkdAaasirrttqefqyqLvvqrvyeegeeelleeeeeeddeakkekdekvfllde 99 
                 Mf+l++++k+lfg++ske +i+ip+GqLylvrp spkg+selifkdAaa+irrt+qefqyqLvvqr+yeegeeel+eee+ee ++++ +kde+vflld+
  EEA19014.1   1 MFMLRNVSKYLFGDASKEAIIDIPQGQLYLVRPLSPKGYSELIFKDAAATIRRTGQEFQYQLVVQRAYEEGEEELAEEEDEEGAADALDKDERVFLLDQ 99 
                 9**********************************************************************************999************* PP

     VID27_N 100 eLkfrveekedgekvlaWrdlsgdegdlyeFvvdesvkeeevkqfelvayqcqyErkyrksaekateedLeefe 173
                 +L+fr+  +++gekvlaWrdlsgd gdlyeFv+d+sv++++v++fe++a+qcqyErkyr+s ++atee+L+ef+
  EEA19014.1 100 ALHFRSVVRDGGEKVLAWRDLSGDPGDLYEFVCDSSVSPDKVATFESAAVQCQYERKYRRSFQRATEEELQEFS 173
                 ************************************************************************95 PP

  == domain 2  score: -9.1 bits;  conditional E-value: 5
     VID27_N  76 leeeeeeddeakke 89 
                 +e+ee+e++ ++ e
  EEA19014.1 375 EEAEEQEEE-EEDE 387
                 222222221.1112 PP

  == domain 3  score: -9.6 bits;  conditional E-value: 5
     VID27_N  71 geeelleeeeeeddea...kkekde 92 
                  ee+ +eee+eed+ +   + ++de
  EEA19014.1 377 AEEQEEEEEDEEDEGQrseHYDTDE 401
                 3322223333333221222333333 PP

  == domain 4  score: 0.5 bits;  conditional E-value: 0.13
     VID27_N 128 yeFvvdesv.keeevkqfelvayqcqyErkyrksaekateedLeef 172
                   F  +++  ++++++ f  v  ++ +    r+s +k  ee+L+++
  EEA19014.1 512 TTFAPEQKFsQMTSAQPFLGVSNNALFRVDPRQSGNKLVEENLKQY 557
                 56777755515677889***************************99 PP

>> VID27_PH  VID27 PH-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0      0.52   1.9e+03      28      46 ..      48      67 ..      41      78 .. 0.70
   2 !  159.5   0.8   8.1e-51   2.9e-47       1     109 []     234     341 ..     234     341 .. 0.98

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.52
    VID27_PH 28 kaavielgk.weYwLqiege 46
                 a++  +g+ ++Y+L+++ +
  EEA19014.1 48 AATIRRTGQeFQYQLVVQRA 67
                4556666544******9843 PP

  == domain 2  score: 159.5 bits;  conditional E-value: 8.1e-51
    VID27_PH   1 ellaeeeaeLhlfDaesgeFilqeeevkaavielgkweYwLqiegeeekewlgqevsadmnpvfnfeylsfifnyvsedgealSwlLrFkdeeeleefq 99 
                 e+la+e+aeLhlfD++sg+Filq+++v+a+v+e g+w+YwLqi+g e kewlgq+v+ d+npvfnfeylsfifn++ +dg+a+SwlLrFkd+++ e+fq
  EEA19014.1 234 EILAKERAELHLFDFASGTFILQDSDVVATVSEIGNWQYWLQITGTE-KEWLGQSVVGDINPVFNFEYLSFIFNHYADDGSAYSWLLRFKDQPTEERFQ 331
                 5799****************************************999.88************************************************* PP

    VID27_PH 100 ealmralwes 109
                 e+lm+alwe+
  EEA19014.1 332 EGLMQALWEQ 341
                 ********96 PP

>> UPF0149  Uncharacterised protein family (UPF0149)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0     0.059   2.1e+02      35      83 ..      33      82 ..      26     108 .. 0.82
   2 !   15.8   3.8   3.5e-06     0.013     101     155 ..     317     385 ..     234     398 .. 0.65

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.059
                HHHCCCHHHHCCCC........STCHHHHHHHHHHHHHHHHHHCTTTTS- CS
     UPF0149 35 llppeeWlpallge.apafsdeeegeallallkrlyneiaaqLadedefe 83
                +l p+ + ++++++ a+ +  + ++ ++   ++r y+e +++La+e++ e
  EEA19014.1 33 PLSPKGYSELIFKDaAATIRRTGQEFQYQLVVQRAYEEGEEELAEEEDEE 82
                678888999999998777888889999999999************88764 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 3.5e-06
                 H.............HHHHHHHH..HHCTTT.GGG-SSHHHHHHHHHHHHHCT--...-TTTS-SSHHHHHHHH CS
     UPF0149 101 W.............ceGFlqGl..glagddWlkdasseelaelLedlaalarle...iaeeeeedeedeeale 155
                 W              eG +q+l  +l++ +W +++++++ + +L+ +++l++++   +    ee ee+ee+ e
  EEA19014.1 317 WllrfkdqpteerfQEGLMQALweQLNEIKW-EKQKADDRDYVLDAFQDLTMEDaepE---KEEAEEQEEEEE 385
                 1444444444444489***************.56666999**************6551...444444444332 PP

>> DUF3801  Protein of unknown function (DUF3801)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.2     0.024        85      67     145 ..      37     190 ..      25     242 .. 0.66
   2 ?    8.8   0.6   0.00043       1.5      75     119 ..     351     401 ..     350     571 .. 0.78

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.024
     DUF3801  67 kgqteiifraedadainrafqrmkl...........vdkadvsqdaekekedresdd.......................................... 112
                 kg  e+if+ ++a+ i r  q++++           ++   +              +                                          
  EEA19014.1  37 KGYSELIFK-DAAATIRRTGQEFQYqlvvqrayeegEEELAEE-------------Edeegaadaldkdervflldqalhfrsvvrdggekvlawrdls 121
                 666677776.678899999999999555443333332222223.............2334445566666699999999999999999999999999999 PP

     DUF3801 113 ..........................kplqkqe.tkrie...npeeaq......teksn.psetlsdees 145
                                           + +q q  +k  +   +++e++      +++s+ ps + +d ++
  EEA19014.1 122 gdpgdlyefvcdssvspdkvatfesaA-VQCQYeRKYRRsfqRATEEElqefsfEDDSPiPSASPIDSPR 190
                 999999999999999999999999862.333322333334654444445577776666676665555544 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.00043
     DUF3801  75 raedadainrafqrmkl......vdkadvsqdaekekedresddkplqkqe 119
                 +a+d d + +afq+ +       ++ a++++++e+++ed+++++   +++e
  EEA19014.1 351 KADDRDYVLDAFQDLTMedaepeKEEAEEQEEEEEDEEDEGQRSEHYDTDE 401
                 79999************5555555555555555555655555553333332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (788 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1260  (0.0702772); expected 358.6 (0.02)
Passed bias filter:                      735  (0.040995); expected 358.6 (0.02)
Passed Vit filter:                       106  (0.00591221); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.87u 0.30s 00:00:01.17 Elapsed: 00:00:00.47
# Mc/sec: 5078.41
//
Query:       EEA19015.1  [L=404]
Description: oxidative stress response protein Oxr1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.5e-26   92.6   0.1    9.3e-16   58.3   0.1    2.5  2  TLD       TLD
  ------ inclusion threshold ------
       0.41   11.6  15.4       0.12   13.3   4.2    2.5  2  AIM3      Altered inheritance of mitochondria protein 3


Domain annotation for each model (and alignments):
>> TLD  TLD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.9   0.0   1.5e-11   1.4e-07       1      63 [.     150     219 ..     150     250 .. 0.81
   2 !   58.3   0.1     1e-19   9.3e-16      66     138 ..     331     402 ..     304     403 .. 0.94

  Alignments for each domain:
  == domain 1  score: 31.9 bits;  conditional E-value: 1.5e-11
         TLD   1 llyssskdgsslstllekie.....nk.gptllli..kdekkyifGaflsqpwkssnkkfygdsesflfsl 63 
                 l ys ++dgsslstl+ +++     +  ++ +l++  +++++ +fGa+l++  + + + fyg++e+fl+  
  EEA19015.1 150 LAYSLERDGSSLSTLYDHCRktserHPrAGYVLVVrdTSDGGAVFGAYLTDAPHPAPH-FYGTGECFLWRA 219
                 57******************99987334777888877667789**********98888.**********87 PP

  == domain 2  score: 58.3 bits;  conditional E-value: 1e-19
         TLD  66 kfkvykstgknkaylntssdglgfGggqpkfsLwidsslekgtsrhsetfengllsgaseerfkikdiEVWgl 138
                 +fk +  +g n++++++++ +l++Ggg+++++Lwid+s+ekg+s ++ tf+n++ls ++ ++f+i  +E+W++
  EEA19015.1 331 RFKAFPYSGMNDYMIFCETGFLSIGGGDGHYGLWIDDSVEKGVSDSCPTFGNEPLS-DEGSKFDILGLEIWSI 402
                 6899999************99***********************************.69************97 PP

>> AIM3  Altered inheritance of mitochondria protein 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   3.4     0.017   1.5e+02      46      82 ..      76     112 ..      34     118 .. 0.74
   2 ?   13.3   4.2   1.3e-05      0.12      28      80 ..     232     282 ..     225     288 .. 0.59

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.017
        AIM3  46 gkddsdeereededydtstsleslrdprsFppPPlkp 82 
                 +++ s++++ +++++++++   + r ++ F pPPl p
  EEA19015.1  76 NNNTSNANNMNSSRSSSTSLYIPKRTASPFQPPPLTP 112
                 223444444444444444444556999*******987 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 1.3e-05
        AIM3  28 qagKkhykkskekreerdgkddsdeereededydtstsleslrdprsFppPPl 80 
                 +  ++h+++++++  +++++ + de++++ +d++t t+ e     + FppPP 
  EEA19015.1 232 NHTHHHHHHHHHNHTKHNDNHEDDEQESNGHDFHTMTDEE--LQRAGFPPPPS 282
                 5555555555555555533334444445555555555554..46689*****7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (404 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1044  (0.0582297); expected 358.6 (0.02)
Passed bias filter:                      505  (0.0281667); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.27s 00:00:00.86 Elapsed: 00:00:00.44
# Mc/sec: 2782.27
//
Query:       EEA19016.1  [L=531]
Description: endosome-associated ubiquitin isopeptidase (AmsH), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.5e-16   58.9   0.0    1.1e-15   57.7   0.0    1.6  1  JAB         JAB1/Mov34/MPN/PAD-1 ubiquitin protease
      3e-11   43.5   0.1    5.8e-11   42.6   0.1    1.4  1  USP8_dimer  USP8 dimerisation domain
    4.8e-05   23.1   0.1    0.00018   21.3   0.0    1.9  2  Prok-JAB    Prokaryotic homologs of the JAB domain
  ------ inclusion threshold ------
       0.51   10.1   3.3       0.46   10.3   0.5    2.0  2  SurA_N_3    SurA N-terminal domain


Domain annotation for each model (and alignments):
>> JAB  JAB1/Mov34/MPN/PAD-1 ubiquitin protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.7   0.0   2.4e-19   1.1e-15       6     117 ..     355     458 ..     351     459 .. 0.91

  Alignments for each domain:
  == domain 1  score: 57.7 bits;  conditional E-value: 2.4e-19
                 EEEEHHHHHHHHHHHHHHHHHTS--EEEEEEEESSSEEEEEEEEEEESEEEESSECEEEEEHHHHHHHHHHHHHHHCTTSEEEEEEEESSSS-SS--HH CS
         JAB   6 vhleslvllkildhalrtekeeeevmGlliGelnddttveitnvfalpfeetekdvdavsldqeylekksellkklrgrervvGWYhshpditvwlsev 104
                   l ++   ++l+ a +++ ++ e++G+l+G+l ++  + + + ++ ++e t++++++v+++ +      ++++   +++ v+GW+h+hp++t+++s+ 
  EEA19016.1 355 LFLPPNLRHEFLRLAGSNTRRNLETCGILCGTLISN-ALFVSKLLIPEQESTSDTCETVNESVI-----FDYCDS--EDLMVLGWIHTHPTQTCFMSSR 445
                 5677888889999********9**************.999*******************99999.....677777..47******************** PP

                 HHHHHHHHHHHST CS
         JAB 105 dvrtqalyqrmde 117
                 d++t++ yq+m +
  EEA19016.1 446 DLHTHCGYQAMLP 458
                 ***********87 PP

>> USP8_dimer  USP8 dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.6   0.1   1.3e-14   5.8e-11      11     114 ..      12     114 ..       7     115 .. 0.90

  Alignments for each domain:
  == domain 1  score: 42.6 bits;  conditional E-value: 1.3e-14
  USP8_dimer  11 sledLkkladklkkdkknksikrllrsaeklfkkAeeyrlegdeEkAYvlymkylnll.elIrkksdykekkasvkellgdkkankvildklekLkesL 108
                 ++e++  la+   + + n+++k  lr+a+ l+k+Ae y +eg +E+AY l+ +  +l+   + +++d  +++++ + ll  +++ +v ++kle Lk + 
  EEA19016.1  12 NVEQITRLAQDY-EYNPNIPLKYWLRTANSLVKEAEIYEREGHDEQAYLLLFRHAQLVlVNLVNHPDA-KDPSNRRGLLAAENQVRVNIKKLEGLKPQI 108
                 677777777776.888999***************************************999******5.566677888999999***9*********** PP

  USP8_dimer 109 kkrYee 114
                 +krYe+
  EEA19016.1 109 NKRYER 114
                 ****96 PP

>> Prok-JAB  Prokaryotic homologs of the JAB domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       1.8     8e+03      13      41 ..      49      74 ..      43      97 .. 0.62
   2 !   21.3   0.0   3.9e-08   0.00018      15      97 ..     374     455 ..     363     477 .. 0.69

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 1.8
    Prok-JAB 13 rrahpeEtcGlllgkeseseevivvplvn 41
                +r+  +E + lll++     + ++v+lvn
  EEA19016.1 49 EREGHDEQAYLLLFRH---AQLVLVNLVN 74
                5666777777777776...4444444444 PP

  == domain 2  score: 21.3 bits;  conditional E-value: 3.9e-08
    Prok-JAB  15 ahpeEtcGlllgkeseseevivvplvnewsnrfeipdpedslarlkf........earerglevvgiwHSHpggsarPSetDrrdaaalar 97 
                 +   EtcG+l g+  +s+   v +l+         p +e + +++           +++++l v+g +H+Hp+   + S+ D++++++  +
  EEA19016.1 374 RRNLETCGILCGTL-ISNALFVSKLLI--------PEQESTSDTCETvnesvifdYCDSEDLMVLGWIHTHPTQTCFMSSRDLHTHCGYQA 455
                 5678*********9.555555555443........22222222222233345556889**************************9988544 PP

>> SurA_N_3  SurA N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.5    0.0001      0.46      84     145 ..      65     126 ..      44     135 .. 0.86
   2 ?   -0.2   0.1      0.17   7.5e+02      76     111 ..     157     192 ..     148     197 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.0001
    SurA_N_3  84 rqqvldqlidealllqeakklglsvsdeevakeiasipaFqedGkFdkerYkqlLaangltp 145
                  q vl +l++    ++  ++ gl + +++v+  i++ + ++++ +   erY+qlL++++  +
  EEA19016.1  65 AQLVLVNLVNHPDAKDPSNRRGLLAAENQVRVNIKKLEGLKPQINKRYERYQQLLQNREARK 126
                 5678888888888999999**********************7777799********987665 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.17
    SurA_N_3  76 elldelglrqqvldqlidealllqeakklglsvsde 111
                 e++++++l  q+  + i+++   + a+  g+s  +e
  EEA19016.1 157 EAAENKELAVQIAHREINRRETVKRARATGISQDEE 192
                 567779999999999999999999999999976665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (531 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       922  (0.0514251); expected 358.6 (0.02)
Passed bias filter:                      551  (0.0307323); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 3738.38
//
Query:       EEA19017.1  [L=774]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    0.00035   19.7   0.0    0.00073   18.7   0.0    1.5  1  RrnaAD        Ribosomal RNA adenine dimethylase
     0.0028   18.1   6.5     0.0035   17.8   5.6    1.6  1  Fez1          Fez1
  ------ inclusion threshold ------
      0.062   13.1   1.6        1.3    8.7   0.2    2.4  2  DUF5105       Domain of unknown function (DUF5105)
       0.27   11.6   2.4         21    5.5   0.2    3.2  4  TAL_effector  TAL effector repeat


Domain annotation for each model (and alignments):
>> RrnaAD  Ribosomal RNA adenine dimethylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   1.6e-07   0.00073      29     165 ..      85     249 ..      68     298 .. 0.73

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 1.6e-07
                 G...TTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-..HHHHHHHHCHTT..TCCCEEEE-S-CCGHHHHHHHCT.............TTCCCCEEE CS
      RrnaAD  29 e...ekltvleigpGkGilTeeLakra..kqvvvlEld..erLakllqkkls..kdeklkvvhqDflkfetpeevte.............kdsihqefl 105
                     +   +l+++pG  +l+ ++++ +    + ++E +  + + k lq+ +s  ++e++k++++ + + ++    +                 +++ +l
  EEA19017.1  85 LtanKPSVILDLYPGRPVLSSKINDLVqpHRHILVEPRasRTFHKYLQE-FSkkDEERIKIYKEKVHYGSLHG--IGwlelldtylptevPPGMQKDLL 180
                 34547789*******************999******99445699****9.666899*******9999888876..334567778888877777888899 PP

                 EEEE--T...TTHHHHHHHHHH.......GGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHE CS
      RrnaAD 106 vvanlPy...eistqlvkqlle.......esrfglvkmllwlqkefarrllarpgskkrsrlsvlreaft 165
                 v+anl+    +  + +   l+           +  v+ l++l+ e a+ ++  ++ ++r+++ +l ea+ 
  EEA19017.1 181 VIANLTDrafKNASRIWAALVGhtllnrgRFSDWTVRTLMILPPEEAESIIP-RSIRNRRKVAILNEAYS 249
                 9999987333334444444444666564422223577888888888888877.57788888888877764 PP

>> Fez1  Fez1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   5.6   7.8e-07    0.0035      23     155 ..     410     550 ..     396     553 .. 0.80

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 7.8e-07
        Fez1  23 qaevtqklseivalkaqlrelrakleekeeeikeleesl.eektlelevcenelqrkkseaellrekvekleeelkelreelselsleeeeaa...... 114
                 ++e+ ++   +++++aq+  l  +l + e +i+++ee + ++k ++l+  e++l r+  ++  ++e+++k++++ ++ r ++ +l++ ++ a+      
  EEA19017.1 410 KKELVARRRGYFKVRAQVIHLAGDLAQLELQIHSCEEIFiKSKLHSLKLAEEQLYREALKQYSTDEQASKIKRDYTRARASVVHLAKAADAAVdlakqq 508
                 6789999999**************************975388999***********************************9988776555443444333 PP

        Fez1 115 ..lesdeakaqrqe.........aeeleelkreverlraeLkeerqkkeeqa 155
                   +          +         + + +++  e+erl+++L+  r++  +q 
  EEA19017.1 509 ikI----------AslegevakaKLDPTTEPVELERLNSKLADSRKEFADQS 550
                 331..........134455554445566778899999999999999877775 PP

>> DUF5105  Domain of unknown function (DUF5105)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.2     0.016        70      86     142 ..     422     482 ..     393     509 .. 0.78
   2 ?    8.7   0.2    0.0003       1.3      85     130 ..     505     552 ..     491     561 .. 0.87

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.016
                 EEEEEEEEEETTEEEEEEEEE-EE-TTHHHHHHHHH...HHHH.TT-TT--HHHHHHHHHH CS
     DUF5105  86 kvetkvvsisgdkAeVevtvkpidlselkdkleeek...eeyl.denksiskeelekkald 142
                 kv ++v+  +gd A+ e+++   +   +k+kl++ k   e+ + +  k++s++e + k   
  EEA19017.1 422 KVRAQVIHLAGDLAQLELQIHSCEEIFIKSKLHSLKlaeEQLYrEALKQYSTDEQASKIKR 482
                 899******************9999999999887542213333477778887777666554 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.0003
                 -EEEEEEEEEETT..EEEEEEEEE-EE-TTHHHHHHHHHHHHHTT-TT CS
     DUF5105  85 akvetkvvsisgd..kAeVevtvkpidlselkdkleeekeeyldenks 130
                 ak + k+ s +g+  kA+   t  p++l+ l++kl + ++e++d++++
  EEA19017.1 505 AKQQIKIASLEGEvaKAKLDPTTEPVELERLNSKLADSRKEFADQSSE 552
                 5667788889999888999999**********************9987 PP

>> TAL_effector  TAL effector repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.2    0.0047        21      21      32 ..     358     369 ..     349     369 .. 0.82
   2 ?   -3.1   0.0       2.3     1e+04      24      32 ..     424     432 ..     424     432 .. 0.92
   3 ?   -2.9   0.0         2   9.1e+03      23      32 ..     487     496 ..     483     496 .. 0.83
   4 ?    4.3   0.0     0.011        50       5      30 ..     650     674 ..     648     675 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0047
                   T--HHHHHHHHT CS
  TAL_effector  21 GfSradIVkIAg 32 
                   +  ra+IV+IA+
    EEA19017.1 358 ARARAQIVHIAK 369
                   6789*******5 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 2.3
                   HHHHHHHHT CS
  TAL_effector  24 radIVkIAg 32 
                   ra+++++Ag
    EEA19017.1 424 RAQVIHLAG 432
                   79*****98 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 2
                   -HHHHHHHHT CS
  TAL_effector  23 SradIVkIAg 32 
                    ra +V++A+
    EEA19017.1 487 ARASVVHLAK 496
                   6899***995 PP

  == domain 4  score: 4.3 bits;  conditional E-value: 0.011
                   HHHHHHHHHHHHHHHTT--HHHHHHH CS
  TAL_effector   5 QALeAVlahgpaLrqrGfSradIVkI 30 
                    A+e V++ ++ L   G S+ad+Vk+
    EEA19017.1 650 RARESVADMLDKLFP-GQSPADVVKL 674
                   599999999999999.99******96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (774 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       844  (0.0470746); expected 358.6 (0.02)
Passed bias filter:                      518  (0.0288917); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.72u 0.30s 00:00:01.02 Elapsed: 00:00:00.49
# Mc/sec: 4782.83
//
Query:       EEA19018.1  [L=312]
Description: hypothetical protein PMAA_012870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.075   12.7   0.1       0.21   11.4   0.1    1.8  1  PAM2      Ataxin-2 C-terminal region
       0.15   12.4   0.1        0.3   11.4   0.1    1.4  1  PEX-2N    Peroxisome biogenesis factor 1, N-terminal


Domain annotation for each model (and alignments):
>> PAM2  Ataxin-2 C-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1   2.3e-05      0.21       3      17 ..     279     293 ..     277     294 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 2.3e-05
                 ---SSTTSS----TT CS
        PAM2   3 kSkLNPnAkEFVPsf 17 
                 +  LN  A+ FVPs+
  EEA19018.1 279 TRGLNATAPAFVPSS 293
                 667**********97 PP

>> PEX-2N  Peroxisome biogenesis factor 1, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1   3.4e-05       0.3      17      55 ..     195     234 ..     188     238 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 3.4e-05
                 HHHHHHTT.--TT--EEEESSS.--EEE-EEE-SS----- CS
      PEX-2N  17 sklvsqLr.lqenqalelswgdsqpvfLsWveerssssqd 55 
                 ++l sqL+ lq+ q  ++++ +++p +L W +er ++  +
  EEA19018.1 195 PSLSSQLSgLQQPQQQQIQYPQQHPYYLNWHQERGRTRDR 234
                 4688999769999********************9887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (312 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       745  (0.0415528); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.25s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2179.42
//
Query:       EEA19019.1  [L=514]
Description: aldehyde dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     2e-122  409.0   0.0   2.5e-122  408.7   0.0    1.0  1  Aldedh    Aldehyde dehydrogenase family
  ------ inclusion threshold ------
       0.12   12.4   0.1        0.3   11.1   0.1    1.6  1  OmdA      Bacteriocin-protection, YdeI or OmpD-Associated
        0.2   10.7   0.1       0.64    9.0   0.1    1.7  1  LuxC      Acyl-CoA reductase (LuxC)


Domain annotation for each model (and alignments):
>> Aldedh  Aldehyde dehydrogenase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  408.7   0.0  4.2e-126  2.5e-122       9     461 ..      47     498 ..      41     499 .. 0.95

  Alignments for each domain:
  == domain 1  score: 408.7 bits;  conditional E-value: 4.2e-126
                 EEEEETTTCEEEEEEE-B-HHHHHHHHHHHHHHHHHHTTS-HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH---HHHHHHHHH.HHHHHHHHHHHHHHH CS
      Aldedh   9 ievinPatgeviakvpaataedvdaavaaAkeafkawaklpaeeRaeiLrkaadlleerkeelaeletletGkplaearaeve.eaidvlryyaelaek 106
                  + inP+t++++ +vp at +d++ av aAkeaf++w+++ ++eR ++L+ka d+l e ++++ael+t+e+Gkp    r+ v+    d  r+ +  a++
  EEA19019.1  47 AQAINPSTRRPLWDVPVATDDDIETAVVAAKEAFETWSHTHWNERVKYLNKAKDALMEIRDDMAELITQEAGKPPGFCRTIVSpIYFDQTRLLIITASH 145
                 689*****************************************************************************77636789***99999998 PP

                 HSEEEEEE.C.TTEEEEEEEEE-SEEEEEE-SSSCCHHHHHHHHHHHHTT-EEEEEE-TTSHHHHHHHHHHHHHTTS-TTSEEE--SSTCCHHHHHHH- CS
      Aldedh 107 legevlps.s.egklalvrrePlGvvgaItPWNfPlllaawklapalaaGNtvvlKPaeetplsalllaelfeeaglPkgvlnvvtgsgsevgealveh 203
                  e e+  + + ++ + +v++ P+Gvv+aI+P   Pllla+ k+ + l++GNtv++KP++ tp s+l+++  ++   +P+gvl+ ++g ++++g alveh
  EEA19019.1 146 PELETKVVtDnDELRLTVKYVPMGVVAAICPAIHPLLLAVAKIGASLITGNTVIVKPSPFTPYSTLKFVDYIKS-IFPPGVLQALNG-DEKLGPALVEH 242
                 665554443425666677788*****************************************************.8***********.889******** PP

                 TTESEEEEES-HHHHHHHHHHHHCTTSEEEEEE---EEEEE-TTSHHHHHHHHHHHHHHGGGGTSTTSEEEEEEEHHHHHHHHHHHHHHHHT--BS-TT CS
      Aldedh 204 pevdkvsftGstevgrkiakaaaknlkrvtlElGGknplivledaDldkaveaivkgafgnaGQvCiaasrllvqesiydefveklveaakklkvgdpl 302
                 p+++k++ftGst++g+k+++aa+k+lkrvtl l+G+n++i+++d D+  ++ ++  gaf+n+GQ C a++r++++e+iy+ef++ +++ +k +k   +l
  EEA19019.1 243 PDIQKIAFTGSTATGKKVMAAASKTLKRVTLGLSGNNACIIFPDIDVSVVAPQVSVGAFLNSGQSCLATRRIYIHEDIYQEFMQHMIDVVKLWKASPSL 341
                 **********************************************************************************************98875 PP

                 ST.T-SB---SSHHHHHHHHHHHHHHHHTTSEEEE-TTE.SB-SSSTTEE--EEEES-TTTSHHHHS---SSEEEEEEESSHHHHHHHHHSSSEESEEE CS
      Aldedh 303 de.dtdvGPliseaqlekvekyveeakeegaklllGgereeaglekgyfvePtvlanvtpdmriaqeEiFGPVlsvikfkdeeeaieiaNdteyGLaag 400
                     + +GP+ +e +++ v+++v+e k +g +  lG   +e ++e+ ++++P +++n ++d+r++ eE FGP++s+++ kde e+i+++Ndt+ GL+a+
  EEA19019.1 342 PGaGNILGPIQNEGRYRIVKQIVQESKRKGLNFALGN--AEFDEENHFVIQPAIIDNPPHDSRVLMEEAFGPIISLFPWKDETEVINVVNDTKTGLGAS 438
                 433899*****************************99..789999****************************************************** PP

                 EE-SBHHHHHHHHHHS-SSEEEESSSST--TTTSEB--CGGGEES-BSHHHHHHHTEEEEE CS
      Aldedh 401 vftkdleraervaerleaGnvyiNdsttgaaealpfgGvkqSglGreggkegleeytevkt 461
                 +++ d+++a  v e+++aG+v+iN++    ++     G+k+SglG e g egl  y++v+t
  EEA19019.1 439 IWSGDMDHAVAVGEKIQAGMVTINSHPSPLPSG-YLSGWKESGLGGELGTEGLLSYCNVQT 498
                 **************************9999999.************************997 PP

>> OmdA  Bacteriocin-protection, YdeI or OmpD-Associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.1     5e-05       0.3      17      42 ..      75     100 ..      63     102 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 5e-05
        OmdA  17 aakaaFealtpsyrreylrwiesaKr 42 
                 aak+aFe+ ++++ +e++ ++++aK 
  EEA19019.1  75 AAKEAFETWSHTHWNERVKYLNKAKD 100
                 5***********************96 PP

>> LuxC  Acyl-CoA reductase (LuxC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.1   0.00011      0.64      85     258 ..     163     326 ..     150     345 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00011
        LuxC  85 ekaqprglvlhvlsgNvpl.lpvmsilqglLvknvnllkvSssdpflaaallksladvdenhtladslsvvyfksgdtkleeeivqnaD..vvvawGge 180
                  k++p g+v  + ++  pl l+v  i  +l+++n  ++k+S   p+ + +++  ++ + +       l ++   +gd+kl   +v++ D  ++   G+ 
  EEA19019.1 163 VKYVPMGVVAAICPAIHPLlLAVAKIGASLITGNTVIVKPSPFTPYSTLKFVDYIKSIFPP----GVLQAL---NGDEKLGPALVEHPDiqKIAFTGST 254
                 5899***********9997258889*****************9999999999999999885....333444...7788888888877774234455666 PP

        LuxC 181 eaikaiseklkpgkqlikfGakv.SfavvdkealeeealdkaaeraAkDiivfdQqAClspqvvfvekddkieidefae 258
                 ++ k + + +  + + +  G      +++ ++     ++  +a ++         q+Cl+ + +++ +d    ++ef +
  EEA19019.1 255 ATGKKVMAAASKTLKRVTLGLSGnNACIIFPDI----DVSVVAPQVSVGAFLNSGQSCLATRRIYIHED---IYQEFMQ 326
                 666777777766666666664430333333444....66666666666666666666666666666655...5555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (514 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       553  (0.0308439); expected 358.6 (0.02)
Passed bias filter:                      533  (0.0297284); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.63u 0.31s 00:00:00.94 Elapsed: 00:00:00.50
# Mc/sec: 3099.43
//
Query:       EEA19020.1  [L=343]
Description: short-chain dehydrogenases/reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-09   38.0   0.1    6.7e-09   35.5   0.0    2.0  2  adh_short     short chain dehydrogenase
    0.00015   21.7   0.0    0.00025   21.0   0.0    1.3  1  KR            KR domain
     0.0091   15.6   0.0      0.013   15.1   0.0    1.4  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.5   0.0   1.1e-12   6.7e-09       2      91 ..      23     116 ..      22     158 .. 0.82
   2 ?   -0.1   0.0     0.089   5.3e+02     170     189 ..     201     220 ..     183     224 .. 0.71

  Alignments for each domain:
  == domain 1  score: 35.5 bits;  conditional E-value: 1.1e-12
                 EEEEESTTSHHHHHHHHHHHHT..T-EEEEEESCHHHHHHHHHHHHHT..TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--S CS
   adh_short   2 vvlvtGassGIGraiakelake..Gakvvvvdrseekleevakelkee..gakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsg 91 
                 v++ +Ga+sGIG  + k++a++    ++++v+rs+ ++ ++++e++e   g k+++i+ Dv+  ++v+++ e++ +k +++++L +  G     
  EEA19020.1  23 VAVFVGATSGIGEYTLKTFAQQtkEPTIYLVGRSDTAATRIVAECEEInpGGKYVFIKSDVSLLKNVDNVCEQILSKEESINLLFQTQGTMVLD 116
                 7899****************8722456777******************9***********************************9999983333 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.089
                 GTEEEEEEEESSBSSHHHHH CS
   adh_short 170 tgirvnavaPGlvdTdmake 189
                  +++ + + PG+v+T++ k+
  EEA19020.1 201 PNVSFIHIFPGGVRTGFGKD 220
                 2499***********98765 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0   0.0   4.3e-08   0.00025       4      91 ..      25     112 ..      22     122 .. 0.84

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 4.3e-08
                 EEETTTSHHHHHHHHHHHHHH.S-EEEEE-SS..--HHHHHHHHHHHHT..T-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---- CS
          KR   4 litGGlGgLGlelarwlaekg.arhlvllsRsaaadedskaliaeleal..gaevevvaaDvsdkdavealleeikaeeppikGvihaAgv 91 
                 + +G++ g+G  + ++ a++  + ++ l++Rs   d ++++ +ae+e+   g +  +++ Dvs  ++v ++ e+i ++e++i+  +++ g+
  EEA19020.1  25 VFVGATSGIGEYTLKTFAQQTkEPTIYLVGRS---DTAATRIVAECEEInpGGKYVFIKSDVSLLKNVDNVCEQILSKEESINLLFQTQGT 112
                 568*****************97889*******...44445577777776557789999***********************9999887654 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   2.1e-06     0.013       1      92 [.      28     119 ..      28     227 .. 0.80

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 2.1e-06
                   TTTTSHHHHHHHHHHHTT-E..EEEEESSGGHHHHHHHHHHHTT..SE.E.EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH- CS
  adh_short_C2   1 GaasgIGraiAkalaeeGae..vvltdlneeakkrveelaeelg..ae.v.lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpflets 91 
                   Ga sgIG+ + k++a++  e  + l+ +++ a+ r+ +  ee++   + v ++ DV+  ++v+++ e++ +k ++++ l+   g +        + +
    EEA19020.1  28 GATSGIGEYTLKTFAQQTKEptIYLVGRSDTAATRIVAECEEINpgGKyVfIKSDVSLLKNVDNVCEQILSKEESINLLFQTQGTMVL------DKT 118
                   999*************98774477777777776665555556554444457****************************999887765......444 PP

                   H CS
  adh_short_C2  92 r 92 
                    
    EEA19020.1 119 S 119
                   4 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (343 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       380  (0.0211947); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.50
# Mc/sec: 2055.67
//
Query:       EEA19021.1  [L=380]
Description: pectate lyase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.5e-15   57.4  10.6    4.3e-14   52.6  10.6    2.2  1  Pec_lyase_C   Pectate lyase
     0.0012   18.7  14.4     0.0037   17.1   5.1    2.4  2  Beta_helix    Right handed beta helix region
  ------ inclusion threshold ------
      0.088   12.6   0.1       0.23   11.2   0.1    1.8  1  Latrotoxin_C  Latrotoxin C-terminal domain


Domain annotation for each model (and alignments):
>> Pec_lyase_C  Pectate lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.6  10.6   7.2e-18   4.3e-14      31     211 .]     124     296 ..     108     296 .. 0.82

  Alignments for each domain:
  == domain 1  score: 52.6 bits;  conditional E-value: 7.2e-18
  Pec_lyase_C  31 isvesnetiiGiiGtngkltnigilvidnssnvivrnlvikt..dgsakdgDairidnsanvWvDHveisdksfeddkttdkdvqfdkaldikkasdy 126
                  i+v s++t+iG  Gt g++   g+++++++sn+i++n+ i          gDai +d    vW+DHv+                  + ++    a + 
   EEA19021.1 124 ITVASHKTLIG-SGTSGVIKGKGLRIVSGASNIIIQNIAITDinARYVWGGDAITLDGADMVWIDHVTTARI------------GRQHLVLGTTADNR 208
                  7899*******.9***************************98765666789*******99*******86532............23344544555667 PP

  Pec_lyase_C 127 vtisnslfeqhkk..tiliGhsddnssqdkGklrvtlhhnvyedvteRaPlvRy.GsiHaynnvyvnkyllsfgvaqsgsvLsEsnsF 211
                  vt+sns+f+++    ++ +G +      d     +t+  n+  +   R P++ +   +Ha nn +   +  +f++++ g vL E+n+F
   EEA19021.1 209 VTVSNSYFNGVTShsATCDGYTYWGIYLDGSSDLITFKGNYIYHFSGRSPKIQGnTLLHAVNNYWYDSTGHAFEIGTGGMVLAEGNVF 296
                  *********98651145677775555556666779***************66651679*****889999******************9 PP

>> Beta_helix  Right handed beta helix region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.7   6.6     0.002        12      44     114 ..     141     220 ..      95     231 .. 0.63
   2 !   17.1   5.1   6.2e-07    0.0037       8      91 ..     206     300 ..     200     327 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.002
                 -SS-SEEE-TT.-S-EEES-EEE---......SEEE-TT--S--EEES-EEES-SS-SEE-TT-S-..-EEES-EEESTT CS
  Beta_helix  44 nsgsGiyilgs.snntisnntisdnn......gggialfgasnnlienneitdnggsGiylnyssn..ntienNiidnna 114
                   g G++i ++ sn++i+n  i+d n      g++i l+ga+ + i+  +  + g+  + l ++ +  +t++n+++++++
  EEA19021.1 141 IKGKGLRIVSGaSNIIIQNIAITDINaryvwgGDAITLDGADMVWIDHVTTARIGRQHLVLGTTADnrVTVSNSYFNGVT 220
                 45555555544577777777777777777777777777777777777777777777777666533313555555555544 PP

  == domain 2  score: 17.1 bits;  conditional E-value: 6.2e-07
                 S-E.EEESEEEES-..........SS-SEEE-SSS-..EEES-EEES-SS-SEEE-TT-S-EEES-EEE---SEEE-TT--S--EEES-EEES-S CS
  Beta_helix   8 ssnvtiknntisns..........ggyGiylrgssn.vvienneiannsgsGiyilgssnntisnntisdnngggialfgasnnlienneitdng 91 
                 ++ vt++n+ ++++           + Giyl+gss+ +++++n+i++ sg    i+g +     nn+++d++g ++ +  ++ +l e+n + + +
  EEA19021.1 206 DNRVTVSNSYFNGVtshsatcdgyTYWGIYLDGSSDlITFKGNYIYHFSGRSPKIQGNTLLHAVNNYWYDSTGHAFEIGTGGMVLAEGNVFQNIN 300
                 445788888888888899999999999********9999999*****99999999998999999********77777777777888888877764 PP

>> Latrotoxin_C  Latrotoxin C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.1   3.9e-05      0.23      12      46 ..      93     128 ..      86     169 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 3.9e-05
  Latrotoxin_C  12 nvciakkfncqlynpgs.sesitydealvnginite 46 
                   +++i ++  c  y+pg+ s s+tyd+a v gi ++ 
    EEA19021.1  93 QLAINQNNWCTNYEPGApSVSVTYDNAGVLGITVAS 128
                   556788888*******7589***********99864 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (380 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       391  (0.0218082); expected 358.6 (0.02)
Passed bias filter:                      259  (0.0144459); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.56u 0.31s 00:00:00.87 Elapsed: 00:00:00.52
# Mc/sec: 2201.29
//
Query:       EEA19022.1  [L=399]
Description: protein kinase domain-containing protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.6e-15   56.5   0.0    9.7e-15   54.6   0.0    1.9  2  Pkinase         Protein kinase domain
     0.0076   15.6   0.0      0.037   13.3   0.0    2.0  2  Pkinase_Tyr     Protein tyrosine kinase
  ------ inclusion threshold ------
      0.012   14.5   0.0      0.017   13.9   0.0    1.2  1  Pkinase_fungal  Fungal protein kinase
      0.022   14.7   0.1      0.037   14.0   0.1    1.3  1  APH             Phosphotransferase enzyme family
      0.063   12.9   0.0        0.1   12.2   0.0    1.2  1  RIO1            RIO1 family


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0       1.9   6.9e+03       7      18 ..      75      86 ..      73      88 .. 0.87
   2 !   54.6   0.0   2.7e-18   9.7e-15      23     257 ..     110     393 ..     104     396 .. 0.76

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 1.9
                EEEESSEEEEEE CS
     Pkinase  7 lGeGsfGkVyka 18
                 G+G  ++Vyka
  EEA19022.1 75 FGRGVWSTVYKA 86
                69********98 PP

  == domain 2  score: 54.6 bits;  conditional E-value: 2.7e-18
                 TTEEEEEEEEECHCHCHHHH..HHHHHHHHHHHHHS..CTTB--EEEEEEESSEEEEEEE--TTEBHHHHHH.....HHSS--HH........HHHHHH CS
     Pkinase  23 tgkivAvKkikkekakkkke..kkvlrEikilkklk..hpnivrlyevfeekdelylvleyveggeladlle.....rkgslsee........eakkia 104
                 t++ vAvK   +++a +  +   ++l+ i+ +++++   +++v +y+++ ++++l+l    ++   l +++e     +++s+s +        + +++a
  EEA19022.1 110 TSRVVAVKSPLRRDAYSILRaeAHILSRITTVQSTSndKDYVVPFYGYIPQSHSLVLQAIPLS---LSTHIEtcadsARKSFSTRtmfdpvtpHWRDLA 205
                 67889999988888887766678899999999988878999*******998777665554444...5555554556766667776788888999***** PP

                 HHHHHHHHHHH.HTTEE-SS-SGGGEEEE.TTTE...........EEE-SGTTSEESSSSCS................BCTTTSCGGGS-HHHH..... CS
     Pkinase 105 kqilegleylH.skgiiHrDlKpeNiLid.ekge...........lKitDFGlakelesssk................ltsfvgtseYlAPEvl..... 169
                 +q+++gl++lH + g++H D+Kp+NiL+  + +               +DF  a  ++s s+                  +   t+ + APE+l     
  EEA19022.1 206 TQLIKGLDWLHrEIGLVHGDIKPHNILLRpR-QTaslsedefeydALYADFSSAHFISSPSSsgsgstslttaedtptGGEGALTPPFAAPELLtlsam 303
                 ***********6668**************53.3336667777887889***********9999*********999877677889************999 PP

                 .TTSCB.SHHHHHHHHHHHHHHHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCTSHH...HHHTTS-HHHHHHHHHHT-SSGCCSTTHHH CS
     Pkinase 170 .keney.skkvDvWslGvilyelltgkppfsgekgkekvekeldqlekilkilgetkeklpeaseiseeakdllkkllkkdpkkRltaee 257
                  ++++  ++++D+++l+++l+   tg  + ++ ++  +  ++ ++  + l+ ++   ++++  +  +  + +++++ ++k+   R+ta+e
  EEA19022.1 304 kSSTPLsTPASDIFALALTLLAAATGDVLIYAGTSAMQRLAMSREGWRALDYVRSGANASRLGRGRDGFVGKVVENAIAKEAAMRPTARE 393
                 877888899******************999966555555555555444444444444444444444555666666666666666666665 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.3   0.0     1e-05     0.037      26     145 ..     109     242 ..      72     250 .. 0.62
   2 ?   -0.7   0.0       0.2   7.2e+02     158     200 ..     279     328 ..     271     357 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1e-05
                  SSEEEEEEEEE.STTSSH..HHHHHHHHHHHHHHTS..-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHT...........CTTTSBHHHHHH CS
  Pkinase_Tyr  26 kkevkVavKtl.keeate..eekeelleeakimkkl..khpnivkllgvctkeepllivteyvkgGdLlkfLrkk...........ekekltlkdlls 107
                   ++  VavK+  +++a +  + ++++l+ +++ +++  +++ +v ++g + +++   +v++ ++  +L++++++            +     + +  +
   EEA19022.1 109 PTSRVVAVKSPlRRDAYSilRAEAHILSRITTVQSTsnDKDYVVPFYGYIPQSH--SLVLQAIPL-SLSTHIETCadsarksfstrTMFDPVTPHWRD 203
                  556667777653222222113355566666666666445566888888777544..455555555.45555555555555555544333344556678 PP

                  HHHHHHHHHHHHHHT.TEEEST-SGGGEEEEETTEEEE- CS
  Pkinase_Tyr 108 falqvAkGmeyLesk.klvHrdlaarNvLlsenkvvkis 145
                  +a+q+ kG+++L+++  lvH d+   N+Ll+ ++++ +s
   EEA19022.1 204 LATQLIKGLDWLHREiGLVHGDIKPHNILLRPRQTASLS 242
                  99**********98636*************988877665 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.2
                  EEEETTSSTSGGGGS-HHHHHHSE.......EEHHHHHHHHHHHHHHHHT CS
  Pkinase_Tyr 158 eyvkkeeaklpvkWmapEslkekk.......ftsksDvWsfGvllwEift 200
                  ++ + +e+ l   + apE l+ +         t +sD+++ + +l   +t
   EEA19022.1 279 DTPTGGEGALTPPFAAPELLTLSAmksstplSTPASDIFALALTLLAAAT 328
                  55566778888899999998877656777777889999999988876665 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   4.9e-06     0.017     315     367 ..     208     266 ..     204     300 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 4.9e-06
  Pkinase_fungal 315 aIkghrsLflkagiLHrDiSenNilitdskke......gerkglLiDLDlakelsddss 367
                      Ikg+  L++++g++H Di  +Nil+   ++        e   l +D+  a  +s +ss
      EEA19022.1 208 LIKGLDWLHREIGLVHGDIKPHNILLRPRQTAslsedeFEYDALYADFSSAHFISSPSS 266
                     699***********************933333444433566677777777777776544 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.1     1e-05     0.037     162     184 ..     210     237 ..     159     240 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1e-05
                 S.....SS-EEEE-SS-SGGGEEEC..T CS
         APH 162 g.....elptvllHgDlhpgNllvdpdd 184
                 +     + + +l+HgD++p+N+l++p++
  EEA19022.1 210 KgldwlHREIGLVHGDIKPHNILLRPRQ 237
                 13445678899*************9665 PP

>> RIO1  RIO1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   2.8e-05       0.1     106     141 ..     200     235 ..     187     240 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2.8e-05
                 HHHHHHHHHHHHHHHHHHTSTEEESS-STTSEEEET CS
        RIO1 106 eaeelyeevleemrklykeaglvHaDLSeyNvlvde 141
                 ++++l+ ++++ +  l +e glvH+D+   N+l+  
  EEA19022.1 200 HWRDLATQLIKGLDWLHREIGLVHGDIKPHNILLRP 235
                 5778899999*9*********************975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (399 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       401  (0.022366); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.44
# Mc/sec: 2717.51
//
Query:       EEA19023.1  [L=820]
Description: isocitrate dehydrogenase Idp1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.1e-70  237.6   0.0    2.7e-70  237.2   0.0    1.1  1  Iso_dh          Isocitrate/isopropylmalate dehydrogenase
    7.8e-17   61.9   0.0    1.3e-15   58.0   0.0    2.6  3  HAD_2           Haloacid dehalogenase-like hydrolase
    6.6e-09   36.4   0.0    1.5e-08   35.2   0.0    1.6  1  Hydrolase       haloacid dehalogenase-like hydrolase
     0.0021   18.1   0.0     0.0046   17.0   0.0    1.5  1  Hydrolase_like  HAD-hyrolase-like


Domain annotation for each model (and alignments):
>> Iso_dh  Isocitrate/isopropylmalate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  237.2   0.0   6.1e-74   2.7e-70       2     348 .]     416     807 ..     415     807 .. 0.91

  Alignments for each domain:
  == domain 1  score: 237.2 bits;  conditional E-value: 6.1e-74
                 EEEEEESTTHHHHHHHHHHHHHHHHHHHT-EEEEEE---THHHHHHHSSSS-HHHHHHHHHSSEEEEEE---CSSSSSSHHH.HHHHHHHHTT.EEEEE CS
      Iso_dh   2 iallegdgiGpevveaalkvlkaakekaglelefeevdvGgaaidetgeplpeetleaikeadvvllgavgtpkekevrpen.gLlaLrkeld.lfanl 98 
                 + ++ ++ +G+e+++ +++ +k++   ++l+++++++d+G +++d+t+++++ +++eaik++ v +++a++tp+  e+r+++  L++++ +++ +++n+
  EEA19023.1 416 VKNPVVELDGDEMTRIIWQDIKDKFIFPYLDIDLKYYDLGLEYRDQTDDQVTVDAAEAIKKYGVGVKCATITPD--EARVKEfNLKKMWLSPNgTIRNI 512
                 66788999******************************************************************..55555556********99***** PP

                 EEEE-B.CCTTCCSSBTHHHHCT.-EEEEEEE-SSCGGCSSEEEEET.....................TG.GGGEEEEEEEEEHHH.HHHHHHHHHHHH CS
      Iso_dh  99 rpvkvf.eklkvksplkrevvee.vdlvivReltggiYfgeekekkg.....................sifteevavdtklyseee.ieriaraafelA 173
                 ++++vf e+++  ++++  v+++   ++i R+++g++Y+++++ + g                       f +  +v   +y+++e i  +a+ +f++A
  EEA19023.1 513 LNGTVFrEPIVIDNIPR-LVPGWkQPIIIGRHAFGDQYRAKDQIIPGegtleviftpkggeperikvyD-FAGP-GVAQTQYNTDEsIIGFAHSSFKMA 608
                 ******88888888888.7****888*******************999***************997532.5555.5556667777769*********** PP

                 HHTTTSEEEEEESTTTTHHHH.HHHHHHHHHHCC......TTTTSEEEEEEHHHHHHHHHHSGGGGS.EEEE-HHHHHHHHHHHHHHTTSGCC-EEEEE CS
      Iso_dh 174 lkrgkkkvtlvdKanvlksse.lwrkiveevaee......eypdielehqlvDsaamqlvkspkqfd.VivtkNlfGDilSDeaaalvGslGllpSasl 264
                 l + + ++++++K+++lk+++ ++++i++e++e+      e++++++eh+l+D++++q++ks+   + Vi++kN++GD++SD +a+ +GslGl++S   
  EEA19023.1 609 LLK-EMPLYMSTKNTILKKYDgRFKDIFQEIYEKdykkdfEAKGLWYEHRLIDDMVAQMIKSE--GGfVIAMKNYDGDVQSDIVAQGFGSLGLMTSTLA 704
                 ***.******************************9****************************..445******************************* PP

                 ET.SS-EEEEESS---CCCTTSS-......S-THHHHHHHHHHHHHTTT-HHHH......HHHHHHHHHHHHH.TSCCHHHCTTS.....TCCCHHHHH CS
      Iso_dh 265 ge.kkvaifEavHGsapdiagkdk......aNpiavilSaalmLryslgleeaA......dkiekAvekvlea.givTkDlagea.....akevstsef 344
                  + +     Ea+HG+++++ + ++      +Npia+i+++++ L  + +l+ +       +++e+A+ +++++ +i+TkDla        +  v+t+e+
  EEA19023.1 705 TPdGTAFESEAAHGTVTRHYREHQkgretsTNPIASIFAWTRGLIQRGKLDGTPevvkfaEALEQACVDTVKEdEIMTKDLALARgrkdrEAWVTTREY 803
                 *95556689**************99*******************8876655433334444***********999********98888888889999999 PP

                 HHHH CS
      Iso_dh 345 gdav 348
                  +av
  EEA19023.1 804 LEAV 807
                 9886 PP

>> HAD_2  Haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0      0.96   4.3e+03       1      24 [.      47      70 ..      47     103 .. 0.72
   2 !   58.0   0.0   2.9e-19   1.3e-15      79     177 ..     103     203 ..      88     204 .. 0.92
   3 ?    0.3   0.3      0.15   6.7e+02      11      75 ..     592     660 ..     588     670 .. 0.62

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.96
       HAD_2  1 iiFDlDgTlldteeliiqafnell 24
                +iFDl   lld+  l+ +a+n+  
  EEA19023.1 47 VIFDLLTALLDSWSLWDKATNNDP 70
                79**********999999988755 PP

  == domain 2  score: 58.0 bits;  conditional E-value: 2.9e-19
       HAD_2  79 kpydgvkelLeeLkeagyklgivTsksreaveekleqlgie..syFdvivtsedvekkKPdpeviekaleklklkkeeviyvGDsptDieaakkagikv 175
                  p ++vk++L  Lk +gy lg+v++ s e  ++ l++++    + Fd  vt+e+v+  KP+p++++++l  l++k++e+i+v  s+ D+ +a ++g++v
  EEA19023.1 103 DPWPEVKDTLGRLKVKGYALGVVSNCSIELGRRALQRCETAdsTTFDAFVTAEEVGFYKPHPDTYRAILSALDVKPHEAIFVAGSSGDVVGAAAVGMQV 201
                 5899*********************************99974468****************************************************** PP

       HAD_2 176 ia 177
                 ++
  EEA19023.1 202 VW 203
                 98 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.15
       HAD_2  11 dteeliiqafnelleey.....glselseeelrkliglslrellrklgeseeeeekieellrkyneekkk 75 
                 +t e ii ++++ ++        l   +++ + k++    +++++++ e++  ++++e    +y++++ +
  EEA19023.1 592 NTDESIIGFAHSSFKMAllkemPLYMSTKNTILKKYDGRFKDIFQEIYEKDY-KKDFEAKGLWYEHRLID 660
                 6666666555544444322221555678889999999999999999999744.55555555566665555 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.2   0.0   3.3e-12   1.5e-08     115     210 .]     100     198 ..      60     198 .. 0.91

  Alignments for each domain:
  == domain 1  score: 35.2 bits;  conditional E-value: 3.3e-12
                 HTHHBHTTHHHHHHHHHHTTEEEEEEESSEHHHHHHHHHHTT...GGGESEEEEHHCESSTTTSHHHHHHHHHHHTSTGGGEEEEESSHHHHHHHHHTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase 115 dplkvkpeaaeavasLkaagievvlltgdnpetaeraanqlG...ddyfdaviasdietvakpspegkvaaireLqgkpeevamVGDgvnDaaalaaAg 210
                   + ++pe+++++ +Lk +g+ ++++++ + e  +ra++++      +fda ++++++++ kp+p+ ++a++  L +kp+e ++V  +  D+ ++aa+g
  EEA19023.1 100 SAKDPWPEVKDTLGRLKVKGYALGVVSNCSIELGRRALQRCEtadSTTFDAFVTAEEVGFYKPHPDTYRAILSALDVKPHEAIFVAGSSGDVVGAAAVG 198
                 33448************************************99*88888************************************88888888888776 PP

>> Hydrolase_like  HAD-hyrolase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0     1e-06    0.0046       4      46 ..     161     202 ..     159     206 .. 0.95

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 1e-06
                     TTSSHHHHHHHHHH---GGGEEEEES-TTTHHHHHHHCT-EEE CS
  Hydrolase_like   4 KPepemydfalevlgsdpeevlmiGDrlatDiagAnnaGwksv 46 
                     KP+p +y+++l +l+++p+e +++  +   D+ gA ++G++ v
      EEA19023.1 161 KPHPDTYRAILSALDVKPHEAIFVAGS-SGDVVGAAAVGMQVV 202
                     9**************************.************988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (820 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       680  (0.0379274); expected 358.6 (0.02)
Passed bias filter:                      528  (0.0294495); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.68u 0.29s 00:00:00.97 Elapsed: 00:00:00.43
# Mc/sec: 5680.19
//
Query:       EEA19024.1  [L=939]
Description: C1 tetrahydrofolate synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.4e-255  848.7   0.1   2.2e-255  848.1   0.1    1.3  1  FTHFS          Formate--tetrahydrofolate ligase
    7.9e-67  223.6   1.4    7.9e-67  223.6   1.4    2.0  2  THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase,
    5.3e-38  129.9   0.8    1.4e-37  128.5   0.6    1.9  2  THF_DHG_CYH    Tetrahydrofolate dehydrogenase/cyclohydrolase,
  ------ inclusion threshold ------
      0.015   14.9   0.1      0.054   13.0   0.0    1.9  2  GTP_EFTU       Elongation factor Tu GTP binding domain


Domain annotation for each model (and alignments):
>> FTHFS  Formate--tetrahydrofolate ligase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  848.1   0.1  4.9e-259  2.2e-255       2     554 .]     313     939 .]     312     939 .] 0.98

  Alignments for each domain:
  == domain 1  score: 848.1 bits;  conditional E-value: 4.9e-259
                 -HHHHHHCS----HHHHHHCTT--CCCEEEBSTTEEEE-CHHCCTCTTTS-.-EEEEEEESS--TT--SHHHHHHHHHHHHH.HTT--EEEEE----SH CS
       FTHFS   2 sdieiaqeaklkpieeiaeklglkeeelelyGkykakvslkvlerllkekkkgklilvtaitPtplGeGKttttigLaqaln.klgkkavaalRepslG 99 
                 sdi i++++k+k i++ia+++g++++ele+yG++kakvsl+vl+rl +++++g++ilvt+itPtplGeGK+ttt+gL+qal+ +l++ a+a++R+ps+G
  EEA19024.1 313 SDIAISRAQKPKAITKIAAEVGIAAHELEPYGHTKAKVSLSVLDRL-SHRRNGRYILVTGITPTPLGEGKSTTTMGLTQALGaHLNRIAFANVRQPSQG 410
                 8******************************************976.99********************************99**************** PP

                 HHHCST--SCEETTEEEESHHHHHTTTTSHHHHHHHHHHHHHHHHHHHHHTTTT............................................. CS
       FTHFS 100 PvfgiKGgAaGGGysqvvPmedinLhltGDihaitaannllaalidnrifhene............................................. 153
                 P+fgiKGgAaGGGysqv+Pm+++nLhltGDihaitaannllaa+id+r+fhe++                                             
  EEA19024.1 411 PTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAITAANNLLAAAIDTRMFHEATqkdgalykrlvptkkgkrefqpimfrrlkklgitktdpneltede 509
                 *************************************************************************************************** PP

                 ......T-EECCCE---EEESS--GGGSSEEES-SSTTS---EEE-EEEGGGSHHHHHHHH-SSHHHHHHHHHC-EEEEETTS-EEECCCCT-HHHHHH CS
       FTHFS 154 ......ldidpkkitwkrvlDvndraLRkivvglggkekgvpretgfditvasEimailaLakdledlkerlgrivvaytkdgepvtaedlkvagalav 246
                       ldidp++itw+rvlDvndr+LR +++g++++ekg++r+tgfdi+vasE+mailaL++dl+d++erlgr+vva++k+g+pvt++d++v gal++
  EEA19024.1 510 ihrfarLDIDPETITWRRVLDVNDRHLRGVTIGQAPTEKGLSRQTGFDISVASECMAILALSNDLADMRERLGRMVVATSKNGDPVTCDDIGVGGALTA 608
                 *************************************************************************************************** PP

                 HTTTTTS-EEEEETT--EEEE-----SSSS--B--HHHHHHHHHH............-SEEEEEBSSSTTTHHHHHHHTHHHHHT---SEEEEEEEHHH CS
       FTHFS 247 llkdaikPnlvqtlegtpalvHggPFAniahGcnsviatklalkl............adyvvtEaGFgadlgaekfldikcrasglkpdavvlvatvra 333
                 l+kdaikPn++q+legtp++vH+gPFAni++G+nsv+a+klalkl            +++vvtEaGF++++g e+f++ikcr+sgl pd+vv+vatvra
  EEA19024.1 609 LMKDAIKPNMMQSLEGTPVFVHAGPFANISIGANSVVADKLALKLagtepdedhdskTGFVVTEAGFDFTMGGERFFNIKCRSSGLVPDVVVVVATVRA 707
                 ********************************************************99***************************************** PP

                 HHHHTT.....--C...CCTTS--HHHHHHHHHHHHHHHHHHCTTT--EEEEEE--TT--HHHHHHHHHHH.HCTTSEEEEE-HHHHGGGGGHHHHHHH CS
       FTHFS 334 Lklhgg.....vek...eelkeenlealekGlanlekhienvkkfgvpvvvainkfktDteaelelvkela.eakavevalsevwakGgeGalelaeav 423
                 Lk+hgg     +++   e +++en+++l+kG+ nl+khi+n++++g+pvvva+nkf+tDt+ae+++++e+a +a+a +++ +++wa+Gg+Ga++la++v
  EEA19024.1 708 LKVHGGgpeisPGAplpEVYRTENVDILRKGCVNLRKHIQNARQYGIPVVVAVNKFETDTDAEIAVIREEAiAAGAEDAVPANHWAEGGAGAVDLAKSV 806
                 ******8777622266799**************************************************999999************************ PP

                 HHHCC-.-.---SS-TTS-HHHHHHHHHHHTT--SEEEE-HHHHHHHHHHHHTTCTTS-EEEE--SSSSSSSTT--SS--S-EEEEEEEEEETTTTEEE CS
       FTHFS 424 vealee.kefkflYdlelsieekietiakeiYgadgvelseeakkklkklekqgldklpvciaKtqySlsddpklkgapegftltvrevrlsaGagfiv 521
                 ++a ++ k+fk+lY+le s++e+i++iak +Ygad+ve+se a+kk+++++kqg+++lp+c+aKtqySls+dp+lkgap+gft+++r+vrlsaGag+++
  EEA19024.1 807 ITASSQpKDFKLLYSLEGSVQERIDQIAKVMYGADKVEFSELAQKKVDTYTKQGYGNLPICVAKTQYSLSHDPALKGAPTGFTVPIRDVRLSAGAGYLY 905
                 *****8799****************************************************************************************** PP

                 EESST--SS----SS-GGGC-EE-TT.SEEES-- CS
       FTHFS 522 alageimtmPGlpkkpaaekidvdee.gkieGlf 554
                 ala++i+t+PGlp+ p + ++dvd   g+i Glf
  EEA19024.1 906 ALAADIQTIPGLPTAPGYLNVDVDPVtGEIDGLF 939
                 ************************988*****98 PP

>> THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  223.6   1.4   1.8e-70   7.9e-67       3     158 ..     127     290 ..     125     292 .. 0.97
   2 ?   -1.6   0.2      0.32   1.4e+03     131     154 ..     370     393 ..     367     398 .. 0.83

  Alignments for each domain:
  == domain 1  score: 223.6 bits;  conditional E-value: 1.8e-70
                    HHHHHHHTT..--SS--HHHHHHHHHHHHCT---TT-EEEEE---TTTHHHHHHHHHCTT-EEEEE-TTSCCHHHHHCCSSEEEE-SS-TT-B-GG CS
  THF_DHG_CYH_C   3 lnlgrlvkg..eeallpctpkgvvellketgielegkkvvvvGrsnivgkplallLleknatVtvchsktkdlaeitreadivvvavGkpelikae 96 
                    +++g l+k+  ++ ++pctp+gv+ell+ +g++ +gk++vvvGrs+ivg+p++ lL++++atVtvchsktk+l ei+++adivv+a+G+pe+ik+e
     EEA19024.1 127 MSIGALAKRggQPLFVPCTPQGVMELLRVSGVDPAGKEAVVVGRSDIVGSPVSYLLKNADATVTVCHSKTKNLGEILKRADIVVAAIGQPEFIKGE 222
                    6799999988899*********************************************************************************** PP

                    GS-TT-EEEE---EEC......-TTEEE-SB-HHHHCTTSSEE--TTTSCHHHHHHHHHHHHHHHHHC CS
  THF_DHG_CYH_C  97 mvkegavviDvGinrv......ekgklvGDvdfeevkevasaitPvpgGVGpmTvamllkntleaakr 158
                    ++k+gavviDvG+n +      +++klvGDv+fe++ evas itPvpgGVGpmTvamllkn++++ak 
     EEA19024.1 223 QLKPGAVVIDVGTNYIpdetkkSGQKLVGDVHFESAVEVASQITPVPGGVGPMTVAMLLKNVVSSAKS 290
                    ********************999999**************************************9986 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.32
                    SEE--TTTSCHHHHHHHHHHHHHH CS
  THF_DHG_CYH_C 131 saitPvpgGVGpmTvamllkntle 154
                      itP p G G+ T++m l++ l 
     EEA19024.1 370 TGITPTPLGEGKSTTTMGLTQALG 393
                    569**************9988765 PP

>> THF_DHG_CYH  Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  128.5   0.6   3.2e-41   1.4e-37       2     116 .]       6     122 ..       5     122 .. 0.98
   2 ?   -3.0   0.0       1.9   8.4e+03      50      92 ..     327     369 ..     324     371 .. 0.78

  Alignments for each domain:
  == domain 1  score: 128.5 bits;  conditional E-value: 3.2e-41
                  --HHHHHHHHHHHHHHHHHHHHHH..T---EEEEEEES--HHHHHHHHHHHHHHHHTT-EEEEEEE-TT--HHHHHHHHHHHHH-TT--EEEE-SS-S CS
  THF_DHG_CYH   2 ldGkalakeireelkeeveklkek..gvkpkLavilvgddpasevYvrnkkkaceevGieseliklpedvseeellklieelneddsvdGilvqlPlp 97 
                  +dG+a+ak+ire+lk e+++l+ k  +++p+L++ +vgd+ +s++Yvr+k ka+ee++i +++ik+pe+++e+ell +ie+ n+d +v+G+lvqlPlp
   EEA19024.1   6 IDGNAIAKDIREKLKTEIAELQTKnpRFRPNLVIYQVGDRSDSSTYVRMKLKAAEEANILCSIIKFPETITEAELLFEIEKSNNDAEVHGVLVQLPLP 103
                  8********************9955699********************************************************************** PP

                  TTS-HHHHHCCS-GGGBTT CS
  THF_DHG_CYH  98 khidekaileaispeKDVD 116
                  +hi+e+ai++a++ eKDVD
   EEA19024.1 104 SHISEHAITSAVADEKDVD 122
                  ******************9 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.9
                  HHHHHHTT-EEEEEEE-TT--HHHHHHHHHHHHH-TT--EEEE CS
  THF_DHG_CYH  50 kkaceevGieseliklpedvseeellklieelneddsvdGilv 92 
                  +k ++evGi  ++ +   +++ +  l+++++l+++ +   ilv
   EEA19024.1 327 TKIAAEVGIAAHELEPYGHTKAKVSLSVLDRLSHRRNGRYILV 369
                  6889999999999988888888888888888888877666665 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0      0.42   1.9e+03      14      29 ..     379     394 ..     375     403 .. 0.82
   2 ?   13.0   0.0   1.2e-05     0.054     107     147 ..     738     779 ..     685     865 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.42
                 SSHHHHHHHHHHHTTS CS
    GTP_EFTU  14 hGKtTLtdrLlyktga 29 
                  GK+T+t  L++++ga
  EEA19024.1 379 EGKSTTTMGLTQALGA 394
                 7******999998886 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 1.2e-05
                 STHHHHHHHHHHHHTTTEEEEEEESCGST.HHHHHHHHHHHH CS
    GTP_EFTU 107 vepqteevlrlalkegvpiivfiNKmDrl.kaelkeiveevk 147
                  +++ +++++ a+++g+p++v++NK     +ae+  i ee+ 
  EEA19024.1 738 GCVNLRKHIQNARQYGIPVVVAVNKFETDtDAEIAVIREEAI 779
                 578899*******************98776788777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (939 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       462  (0.0257683); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.75u 0.31s 00:00:01.06 Elapsed: 00:00:00.48
# Mc/sec: 5877.54
//
Query:       EEA19025.1  [L=340]
Description: eukaryotic translation initiation factor 3 subunit 2i, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    8.7e-27   92.8   0.3    4.9e-08   33.5   0.1    6.3  6  WD40         WD domain, G-beta repeat
    1.3e-12   47.8   0.1      0.043   14.1   0.0    5.6  6  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
     0.0015   17.3   0.0       0.03   13.0   0.0    2.0  2  Nup160       Nucleoporin Nup120/160
  ------ inclusion threshold ------
      0.014   14.7   0.0        1.4    8.2   0.0    2.7  2  WD40_like    WD40-like domain
       0.13   11.2   0.1        8.2    5.2   0.1    2.2  2  PALB2_WD40   Partner and localizer of BRCA2 WD40 domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.0   5.6e-05       0.2       7      37 ..       6      37 ..       3      37 .. 0.93
   2 !   33.5   0.1   1.4e-11   4.9e-08       2      38 .]      43      80 ..      42      80 .. 0.93
   3 ?    4.5   0.0      0.02        72       2      27 ..      85     110 ..      84     126 .. 0.73
   4 !    6.9   0.0    0.0034        12      18      38 .]     160     180 ..     141     180 .. 0.83
   5 !   14.1   0.0   1.8e-05     0.066       7      36 ..     190     222 ..     184     224 .. 0.83
   6 !   13.2   0.0   3.6e-05      0.13       5      36 ..     287     319 ..     283     321 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 5.6e-05
                EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40  7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37
                l GH  s + ++f++dg++l+s  +D+ v +W
  EEA19025.1  6 LQGHeRSLNQIKFNRDGDLLFSVAKDKIVGVW 37
                679*888**************99******999 PP

  == domain 2  score: 33.5 bits;  conditional E-value: 1.4e-11
                EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38
                + l+t+ GH + ++ +++sp+  +la+Gs D++vr+W+
  EEA19025.1 43 ERLGTYAGHqGAIWTVDVSPNTVLLATGSADNSVRLWN 80
                6789*****777*************************8 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.02
                 EEEEEEESSSSEEEEEEETTSSEEEE CS
        WD40   2 qclrtltGHssvtslafspdgawlas 27 
                 +c+++++  + v  + fspdg+ l++
  EEA19025.1  85 ECVKVWEFPTAVKRVEFSPDGSQLLA 110
                 6666666445589999******9876 PP

  == domain 4  score: 6.9 bits;  conditional E-value: 0.0034
                 EETTSSEEEEEETTSEEEEEE CS
        WD40  18 fspdgawlasGsdDgtvriWd 38 
                 +s  ++++++G++Dg+v  +d
  EEA19025.1 160 WSYLSKYIIAGHEDGSVSQYD 180
                 7778899**********9887 PP

  == domain 5  score: 14.1 bits;  conditional E-value: 1.8e-05
                 EESS.SS..EEEEEEETTSSEEEEEETTSEEEE CS
        WD40   7 ltGH.ss..vtslafspdgawlasGsdDgtvri 36 
                   +H  +  +++++fs d ++++++s+D+t +i
  EEA19025.1 190 VQAHeLDlqINDIQFSADRTYFITASRDKTAKI 222
                 567864467*********************998 PP

  == domain 6  score: 13.2 bits;  conditional E-value: 3.6e-05
                 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS
        WD40   5 rtltGH.ssvtslafspdgawlasGsdDgtvri 36 
                 +  +GH ++ + +a++p g+  asG++Dg vr+
  EEA19025.1 287 GRVRGHfGPLNTIAVHPAGTAYASGGEDGYVRV 319
                 5679**888************99*********8 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.7   0.0    0.0049        18      37      80 ..       9      52 ..       5      58 .. 0.85
   2 !   14.1   0.0   1.2e-05     0.043      35      80 ..      49      94 ..      40     104 .. 0.82
   3 ?    0.7   0.0      0.18   6.5e+02      39      58 ..      94     113 ..      88     132 .. 0.71
   4 !   13.1   0.0   2.4e-05     0.086      37      80 ..     151     194 ..     145     197 .. 0.91
   5 !    8.0   0.0   0.00095       3.4      35      82 ..     193     240 ..     190     249 .. 0.89
   6 ?    1.5   0.0       0.1   3.7e+02      42      68 ..     297     323 ..     279     337 .. 0.84

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0049
  ANAPC4_WD40 37 edsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvks 80
                 ++++ ++++++ dg lL  + +d  v +  a +g+ + ++  ++
   EEA19025.1  9 HERSLNQIKFNRDGDLLFSVAKDKIVGVWFAANGERLGTYAGHQ 52
                 6678899*********************9999999887776655 PP

  == domain 2  score: 14.1 bits;  conditional E-value: 1.2e-05
  ANAPC4_WD40 35 dkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvks 80
                 +++++ +  +  +p+  lLa + +d++vrl ++++g++v+ ++  +
   EEA19025.1 49 AGHQGAIWTVDVSPNTVLLATGSADNSVRLWNIKTGECVKVWEFPT 94
                 5677888889999**************************9887654 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 0.18
  ANAPC4_WD40  39 sevrsLaWkpdgklLavays 58 
                    v+ ++++pdg+ L  +++
   EEA19025.1  94 TAVKRVEFSPDGSQLLAVTE 113
                  579999******76655544 PP

  == domain 4  score: 13.1 bits;  conditional E-value: 2.4e-05
  ANAPC4_WD40  37 edsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvks 80 
                  eds+ +   W+   k +  +++dg+v+ +da++g+ ++++++++
   EEA19025.1 151 EDSKATVAGWSYLSKYIIAGHEDGSVSQYDAKTGEQLENVQAHE 194
                  678888889******************************99986 PP

  == domain 5  score: 8.0 bits;  conditional E-value: 0.00095
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksek 82 
                  ++ d ++++++++ d + +  a  d + +++++ +  v++s+++++  
   EEA19025.1 193 HELDLQINDIQFSADRTYFITASRDKTAKIISSRNLAVLKSFTTDTPL 240
                  678999************************************998765 PP

  == domain 6  score: 1.5 bits;  conditional E-value: 0.1
  ANAPC4_WD40  42 rsLaWkpdgklLavaysdgevrlldae 68 
                  + +a +p g+  a + +dg vr+++  
   EEA19025.1 297 NTIAVHPAGTAYASGGEDGYVRVHHFD 323
                  67788999**************99876 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.0   0.0   8.5e-06      0.03     221     270 ..      56     100 ..      26     135 .. 0.75
   2 ?    2.3   0.0     0.014        51     216     259 ..     192     237 ..     177     272 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 8.5e-06
                 EET.....TTTEEEEEETT-EEEEEETTTTEEEEEEE--.-SSSTTS--S CS
      Nup160 221 vavavveigqtylfalsrdgkLrvWnlltgkclatidllrdeeaqdesss 270
                  +v+v+  +  +l++ s d+ +r+Wn++tg c+ + + +    +++++++
  EEA19025.1  56 WTVDVSP-NTVLLATGSADNSVRLWNIKTGECVKVWEFP----TAVKRVE 100
                 5566665.77788999*****************998888....3333333 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.014
                 ECEEEEET.......TTTEEEEEETT-EEEEEETTTTEEEEEEE-- CS
      Nup160 216 alsldvavavvei..gqtylfalsrdgkLrvWnlltgkclatidll 259
                 a +ld+ +  ++   ++ty  ++srd++ ++ + +++ +l +++++
  EEA19025.1 192 AHELDLQINDIQFsaDRTYFITASRDKTAKIISSRNLAVLKSFTTD 237
                 5556665555555679*****************9999999998877 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   0.0   0.00039       1.4       3      39 ..      55      91 ..      53     124 .. 0.86
   2 ?    3.3   0.0     0.012        44     184     233 ..     225     276 ..     190     291 .. 0.63

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.00039
   WD40_like  3 iYsidiskkgslilyGgkddkctvlkleslesvsive 39
                i+++d+s++  l++ G+ d+ +++ +++++e v + e
  EEA19025.1 55 IWTVDVSPNTVLLATGSADNSVRLWNIKTGECVKVWE 91
                89****************************9998764 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.012
   WD40_like 184 lkknvilqkidvegkPecillv...ddylivGgsfkyllliNiklnvntfklr 233
                  ++  +l+ + +++ P  ++ +   +dy+i+Gg    + +  + +   +f+ r
  EEA19025.1 225 SRNLAVLKSFTTDT-PLNTAAItpkKDYVILGGGQAAMEVTTTSARQGKFEAR 276
                 33446777777776.44333221337888888888877777776666666655 PP

>> PALB2_WD40  Partner and localizer of BRCA2 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   0.1    0.0023       8.2     193     215 ..      66      89 ..      53     101 .. 0.77
   2 ?    3.9   0.0    0.0058        21     319     350 ..     148     179 ..     120     180 .. 0.87

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.0023
  PALB2_WD40 193 llgt.tvlnniviWnlktGqllkk 215
                 ll+t +++n++ +Wn+ktG  +k 
  EEA19025.1  66 LLATgSADNSVRLWNIKTGECVKV 89 
                 444415789999*******98875 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.0058
  PALB2_WD40 319 lpesdesWslvrWsgtdsqllaGqkdGsvlvy 350
                 ++  d++ ++  Ws  +  ++aG++dGsv  y
  EEA19025.1 148 ITCEDSKATVAGWSYLSKYIIAGHEDGSVSQY 179
                 667789999999****************9877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (340 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       344  (0.0191868); expected 358.6 (0.02)
Passed bias filter:                      302  (0.0168442); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.41
# Mc/sec: 2483.66
//
Query:       EEA19026.1  [L=156]
Description: coactivator bridging factor 1 (Mbf1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-25   89.7   1.5    1.2e-25   89.7   1.5    1.8  2  MBF1      Multiprotein bridging factor 1
    1.2e-10   41.3   0.1      2e-10   40.6   0.1    1.4  1  HTH_3     Helix-turn-helix
    7.5e-05   23.0   0.1    0.00026   21.3   0.0    1.8  2  HTH_31    Helix-turn-helix domain


Domain annotation for each model (and alignments):
>> MBF1  Multiprotein bridging factor 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.7   1.5     2e-29   1.2e-25       1      72 []       4      81 ..       4      81 .. 0.97
   2 ?   -1.8   0.0      0.74   4.4e+03       9      30 ..     115     136 ..     110     151 .. 0.62

  Alignments for each domain:
  == domain 1  score: 89.7 bits;  conditional E-value: 2e-29
        MBF1  1 qDWdsvtvigkkar.....katvaksesalnaArRsGavvetekKfaagtNkaskaq..egqnlaKlDreteelkpkkV 72
                qDWd+vt+ig k+r     ++tv+k++salnaA+RsG v+ tekK +a++N+a ++   egq+l+K+Dr+++++kpk+V
  EEA19026.1  4 QDWDNVTRIGTKHRaggvqRETVVKGRSALNAAQRSGLVIGTEKK-YATGNAAGRTGapEGQHLTKVDRSDDIIKPKTV 81
                8********************************************.9999999888899******************98 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.74
        MBF1   9 igkkarkatvaksesalnaArR 30 
                 i +  ++ t++ +++ l a  R
  EEA19026.1 115 IVQDMERGTATPDQKVLSAMER 136
                 4444455666666666666655 PP

>> HTH_3  Helix-turn-helix
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.6   0.1   3.3e-14     2e-10       1      52 [.      89     142 ..      89     144 .. 0.95

  Alignments for each domain:
  == domain 1  score: 40.6 bits;  conditional E-value: 3.3e-14
                 HHHHHH..HTTHHHHHHHHHHTSSHHHHHHHHTTSSCSBHHHHHHHHHHHTSEH CS
       HTH_3   1 lkelRk..qlglsqeeLAeklGvsrstisriEnGernPsletlkklakaLgvsl 52 
                 +k++R+    +++q+eLA k++ +++ ++++E+G + P++++l +++++L+++l
  EEA19026.1  89 IKKRRNdeGYKMTQKELATKCNTTVTIVQDMERGTATPDQKVLSAMERVLNIKL 142
                 78999988999****************************************987 PP

>> HTH_31  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.1      0.39   2.3e+03      17      36 ..      32      51 ..      17      71 .. 0.60
   2 !   21.3   0.0   4.3e-08   0.00026       2      55 ..      85     139 ..      84     145 .. 0.91

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.39
      HTH_31 17 qeevAerlgvsestlsrlEq 36
                   +A+r+g+   t  ++ +
  EEA19026.1 32 ALNAAQRSGLVIGTEKKYAT 51
                55567777655555445544 PP

  == domain 2  score: 21.3 bits;  conditional E-value: 4.3e-08
      HTH_31   2 LGalLralReraG..LsqeevAerlgvsestlsrlEqGrrgrpspavlealaralg 55 
                  G+  + +R+ +G  ++q+e+A  ++ +++ + ++E+G+ + p   vl a+ r+l+
  EEA19026.1  85 VGEAIKKRRNDEGykMTQKELATKCNTTVTIVQDMERGTAT-PDQKVLSAMERVLN 139
                 588889999999766*************************6.**********9997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (156 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       614  (0.0342462); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.39u 0.27s 00:00:00.66 Elapsed: 00:00:00.41
# Mc/sec: 1130.72
//
Query:       EEA19027.1  [L=544]
Description: amidophosphoribosyltransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.1e-15   56.7   0.0    3.8e-15   55.9   0.0    1.5  1  GATase_7      Glutamine amidotransferase domain
    5.1e-15   55.8   0.0    1.1e-14   54.7   0.0    1.6  1  GATase_6      Glutamine amidotransferase domain
    9.1e-09   35.0   0.0    2.4e-08   33.6   0.0    1.6  1  Pribosyltran  Phosphoribosyl transferase domain
    3.8e-05   22.7   0.0    7.3e-05   21.8   0.0    1.4  1  GATase_4      Glutamine amidotransferases class-II
  ------ inclusion threshold ------
      0.041   13.9   0.2       0.19   11.8   0.2    2.1  1  PA            PA domain


Domain annotation for each model (and alignments):
>> GATase_7  Glutamine amidotransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.9   0.0   1.1e-18   3.8e-15       7     122 ..      90     227 ..      82     228 .. 0.89

  Alignments for each domain:
  == domain 1  score: 55.9 bits;  conditional E-value: 1.1e-18
    GATase_7   7 idseagaQPmvssedgrlvivfnGeiyNykelreeLeakgh.rfrtksDtevllallea................ewgeealerlnGmfAfaiwdeeek 88 
                  ds+a+aQP++ ++   +++++nG ++N +elr++L ++ h +++t+sD+e++l+++++                + + ++++r++G +A   + +   
  EEA19027.1  90 SDSSAEAQPFYVNSPYGICLAHNGNLVNARELRAHLDKEAHrHINTDSDSELMLNIFANelnetgkarvnqedifDALSRMYKRCQGGWACTAMVAGF- 187
                 68899******977777********************9988356*************999***************99*************99998877. PP

    GATase_7  89 rlllaRDrlGikPLyygedk......gdallfaSelkall 122
                  +++ RD++Gi+PL++ge++       + ++faSe  al+
  EEA19027.1 188 GIFAFRDQYGIRPLILGERPsetlpgATDYMFASESIALR 227
                 8*****************9965555434889999998886 PP

>> GATase_6  Glutamine amidotransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.7   0.0   3.2e-18   1.1e-14      12     126 ..      76     214 ..      57     222 .. 0.76

  Alignments for each domain:
  == domain 1  score: 54.7 bits;  conditional E-value: 3.2e-18
    GATase_6  12 devalaHvRlaivglaeeegaqPf.psedgrlllvhNGeiynykelreelpalkglafrsrsDtevllall....eelG......eevlerlrGmfafa 99 
                 ++++++H R  + g + +++aqPf +++  ++ l+hNG   n++elr+ l +++ ++++++sD+e++l+++    +e+G      e+ +++l  m++ +
  EEA19027.1  76 GSMGIGHLRYPTAGSDSSAEAQPFyVNSPYGICLAHNGNLVNARELRAHLDKEAHRHINTDSDSELMLNIFanelNETGkarvnqEDIFDALSRMYKRC 174
                 359*************99999***9999999*********************99999************999999777788888755557777777765 PP

    GATase_6 100 ..iwdk....rentlilardrlgvkplyyavd.......e 126
                    w +    +  +++  rd+ g++pl+ ++         
  EEA19027.1 175 qgGWACtamvAGFGIFAFRDQYGIRPLILGERpsetlpgA 214
                 3335543011334555559*******99998755444444 PP

>> Pribosyltran  Phosphoribosyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.6   0.0   6.8e-12   2.4e-08       9     122 ..     289     410 ..     285     420 .. 0.76

  Alignments for each domain:
  == domain 1  score: 33.6 bits;  conditional E-value: 6.8e-12
                   --EEEEEEETTEEEEEE--GG.GEEEEEEETTTHHHHHHHHHHSTT-EE.-EEEEEE-TTT--EE................EE----TTSEEEEE-S CS
  Pribosyltran   9 paildavarlaaeileeyngk.pdvvvgiargGvpfakiladeLevpla.yvrkvkyrpdgseeaargssdes........rlledpagkkVliVDD 95 
                   +++ d+ a++++eil e++ k +d+v++i+  + p a  +a++L++p+     k +y     + + +g+s+ +           ed+agk Vl+VDD
    EEA19027.1 289 QKMGDKLADKIKEILGEDGIKeIDAVIPIPETSNPSAFSVAQRLNLPYReGFVKNRY--VFRTFIMPGQSARQkgvrrklsAIDEDFAGKCVLLVDD 383
                   6778899**********6665168********************7775433333333..22222222333333344455557899************ PP

                   EESSSHHHHHHHHHHHCC-BSEEEEEE CS
  Pribosyltran  96 ildtGgTllaalelLkekgpeevriav 122
                    +  G+T ++++   +e+g+ +v++a 
    EEA19027.1 384 SIVRGTTSREIVAMAREAGARKVIFAS 410
                   ************************996 PP

>> GATase_4  Glutamine amidotransferases class-II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   0.0     2e-08   7.3e-05      70     187 ..      75     194 ..      68     207 .. 0.79

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 2e-08
    GATase_4  70 ksknvvaHiRkatqGevklenthpFvRelwgrewifAHnGdlke...ykpkl.egrfePv.GsTDsElafCelleelasrfekaepsaeeleralaela 163
                   ++ + H+R  t G+ + ++++pF  +     + +AHnG+l +   ++ +l ++ ++ +  + DsEl++ ++ +el+++  ka+ ++e++++al+ + 
  EEA19027.1  75 PGSMGIGHLRYPTAGSDSSAEAQPFYVN-SPYGICLAHNGNLVNareLRAHLdKEAHRHInTDSDSELMLNIFANELNETG-KARVNQEDIFDALSRMY 171
                 5567799******************865.455799*******662234555564445555256799***********9999.6799***********99 PP

    GATase_4 164 keiaelGvfnlllsdgralfahas 187
                 k+  + G + + +  g  +fa+++
  EEA19027.1 172 KRC-QGGWACTAMVAGFGIFAFRD 194
                 987.46888888888888888877 PP

>> PA  PA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.2   5.2e-05      0.19      21      54 ..     370     410 ..     353     479 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 5.2e-05
          PA  21 gvdvkGkivLvqr.......tfaeKarnAqaaGAagviivn 54 
                  +d++Gk vL  +       t +e ++ A++aGA  vi+++
  EEA19027.1 370 DEDFAGKCVLLVDdsivrgtTSREIVAMAREAGARKVIFAS 410
                 4599***888743345446555*****************94 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (544 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       349  (0.0194657); expected 358.6 (0.02)
Passed bias filter:                      341  (0.0190195); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.55u 0.26s 00:00:00.81 Elapsed: 00:00:00.42
# Mc/sec: 3902.67
//
Query:       EEA19028.1  [L=244]
Description: SH3 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.9e-16   57.1   0.0    1.5e-15   56.5   0.0    1.3  1  SH3_1     SH3 domain
    1.5e-13   50.4   0.0    4.9e-13   48.7   0.0    1.8  2  SH3_9     Variant SH3 domain
    1.7e-08   34.0   0.0    2.6e-08   33.4   0.0    1.3  1  SH3_2     Variant SH3 domain


Domain annotation for each model (and alignments):
>> SH3_1  SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.5   0.0   2.6e-19   1.5e-15       2      47 ..     120     165 ..     119     166 .. 0.98

  Alignments for each domain:
  == domain 1  score: 56.5 bits;  conditional E-value: 2.6e-19
                 ESSSBEXSSTTBXEBSTTEEEEEEEECSSSEEEEEETTSTEEEEEE CS
       SH3_1   2 AlYDYeaeesdELsfkkGDviivleksedgWwkgrlkgtgkeGliP 47 
                 A+Y Y+++++++L ++++D i+vle+ +++Ww+gr+ +t++eG++P
  EEA19028.1 120 AMYAYTPTDAGDLALQPNDRIQVLEHMNNDWWRGRNERTNQEGIFP 165
                 99******************************************** PP

>> SH3_9  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0      0.41   2.4e+03      11      21 ..      21      31 ..      20      34 .. 0.86
   2 !   48.7   0.0   8.3e-17   4.9e-13       1      48 [.     120     169 ..     120     170 .. 0.95

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.41
       SH3_9 11 deLsLqrGDvi 21
                +eL++ ++  i
  EEA19028.1 21 TELEFLTDASI 31
                7*****99877 PP

  == domain 2  score: 48.7 bits;  conditional E-value: 8.3e-17
       SH3_9   1 AlypyepreddeLsLqrGDvitvieesedgWlegsl..tGrtGlvPanyv 48 
                 A+y+y+p+++  L Lq++D+i v+e  +++W++g++  t + G +P++yv
  EEA19028.1 120 AMYAYTPTDAGDLALQPNDRIQVLEHMNNDWWRGRNerTNQEGIFPRSYV 169
                 8***********************998*******97779**********9 PP

>> SH3_2  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.4   0.0   4.4e-12   2.6e-08       8      56 ..     124     171 ..     120     172 .. 0.93

  Alignments for each domain:
  == domain 1  score: 33.4 bits;  conditional E-value: 4.4e-12
                 B-SCGCCB--B-TTEEEEEE..EEEECTTEEEEEE..CCCEEEEEGCGEEE CS
       SH3_2   8 yvgedkseLsfkkGdvikvlslgskdsdgwwegev..gGrvGlfPsslvee 56 
                 y+++d + L ++ +d i+vl   ++ +++ww+g++   ++ G+fP+s+v++
  EEA19028.1 124 YTPTDAGDLALQPNDRIQVL---EHMNNDWWRGRNerTNQEGIFPRSYVRV 171
                 99******************...************767888********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (244 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       541  (0.0301746); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.41
# Mc/sec: 1786.73
//
Query:       EEA19029.1  [L=237]
Description: SH3 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      9e-16   57.2   0.0    1.5e-15   56.6   0.0    1.3  1  SH3_1     SH3 domain
    1.3e-13   50.5   0.0    4.7e-13   48.8   0.0    1.8  2  SH3_9     Variant SH3 domain
    1.5e-08   34.1   0.0    2.5e-08   33.5   0.0    1.3  1  SH3_2     Variant SH3 domain


Domain annotation for each model (and alignments):
>> SH3_1  SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.6   0.0   2.4e-19   1.5e-15       2      47 ..     120     165 ..     119     166 .. 0.98

  Alignments for each domain:
  == domain 1  score: 56.6 bits;  conditional E-value: 2.4e-19
                 ESSSBEXSSTTBXEBSTTEEEEEEEECSSSEEEEEETTSTEEEEEE CS
       SH3_1   2 AlYDYeaeesdELsfkkGDviivleksedgWwkgrlkgtgkeGliP 47 
                 A+Y Y+++++++L ++++D i+vle+ +++Ww+gr+ +t++eG++P
  EEA19029.1 120 AMYAYTPTDAGDLALQPNDRIQVLEHMNNDWWRGRNERTNQEGIFP 165
                 99******************************************** PP

>> SH3_9  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0      0.39   2.3e+03      11      21 ..      21      31 ..      20      34 .. 0.86
   2 !   48.8   0.0   7.9e-17   4.7e-13       1      48 [.     120     169 ..     120     170 .. 0.95

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.39
       SH3_9 11 deLsLqrGDvi 21
                +eL++ ++  i
  EEA19029.1 21 TELEFLTDASI 31
                7*****99877 PP

  == domain 2  score: 48.8 bits;  conditional E-value: 7.9e-17
       SH3_9   1 AlypyepreddeLsLqrGDvitvieesedgWlegsl..tGrtGlvPanyv 48 
                 A+y+y+p+++  L Lq++D+i v+e  +++W++g++  t + G +P++yv
  EEA19029.1 120 AMYAYTPTDAGDLALQPNDRIQVLEHMNNDWWRGRNerTNQEGIFPRSYV 169
                 8***********************998*******97779**********9 PP

>> SH3_2  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.5   0.0   4.1e-12   2.5e-08       8      56 ..     124     171 ..     120     172 .. 0.93

  Alignments for each domain:
  == domain 1  score: 33.5 bits;  conditional E-value: 4.1e-12
                 B-SCGCCB--B-TTEEEEEE..EEEECTTEEEEEE..CCCEEEEEGCGEEE CS
       SH3_2   8 yvgedkseLsfkkGdvikvlslgskdsdgwwegev..gGrvGlfPsslvee 56 
                 y+++d + L ++ +d i+vl   ++ +++ww+g++   ++ G+fP+s+v++
  EEA19029.1 124 YTPTDAGDLALQPNDRIQVL---EHMNNDWWRGRNerTNQEGIFPRSYVRV 171
                 99******************...************767888********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (237 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       510  (0.0284455); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 1767.83
//
Query:       EEA19030.1  [L=1062]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.7e-25   87.7   3.9    2.1e-16   60.3   0.4    4.0  3  Ank_2     Ankyrin repeats (3 copies)
    8.3e-21   74.1   1.6    2.3e-06   28.1   0.1    5.4  5  Ank_4     Ankyrin repeats (many copies)
    1.9e-14   53.4   2.3      0.017   15.6   0.0    5.4  5  Ank       Ankyrin repeat
      2e-14   53.5   1.6    3.6e-06   27.1   0.3    4.0  4  Ank_5     Ankyrin repeats (many copies)
    1.2e-13   49.8   5.9        0.2   12.3   0.0    7.0  8  Ank_3     Ankyrin repeat
    0.00066   19.5   0.0     0.0016   18.3   0.0    1.6  1  IRK       Inward rectifier potassium channel transmembrane do


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.1   0.00055       1.7      12      74 ..     817     885 ..     804     894 .. 0.65
   2 !   60.3   0.4   6.9e-20   2.1e-16       2      81 ..     901     990 ..     900     992 .. 0.91
   3 !   15.9   0.0   4.9e-06     0.015      52      83 .]     994    1025 ..     991    1025 .. 0.93

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00055
       Ank_2  12 lvklLl.egadpn..k..ngktaLhyAakngnleivklLleh..adndgrtpLhyAarsghleivklLle 74 
                 +++lL+ + ++ +  +    + ++ yA ++g++e+++lLl h   ++    +++  +r+g++e+++++l 
  EEA19030.1 817 MLELLIiKMVN-DlaEmyRLLAVIVYAHRKGYTETMRLLLHHaeRTKRKDDIIIELSRQGNTEALRVFLG 885
                 55555543322.23224233455669**************885533556678888888999999998883 PP

  == domain 2  score: 60.3 bits;  conditional E-value: 6.9e-20
       Ank_2   2 hlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinl 81 
                  +Aa+ ++++l+++Ll +g+++n  + ngktaL+ Aa+n ++  ++lLl+h       dn g t+L+ Aa+ g+l +v+lL+ kgadin+
  EEA19030.1 901 LIAAQAEHHSLLEFLLeCGVNVNlqDeNGKTALMEAAMNRDVASAELLLSHnvsidqRDNFGDTALISAAERGYLPVVELLVSKGADINV 990
                 5899999899*******9999999538*************88889*****99996655599*********************99****97 PP

  == domain 3  score: 15.9 bits;  conditional E-value: 4.9e-06
       Ank_2   52 dgrtpLhyAarsghleivklLlekgadinlkd 83  
                   grt+L++A+  + l +vk+L+  gad+ ++d
  EEA19030.1  994 RGRTALMAAIVRQELPLVKYLCAAGADLSITD 1025
                  69********************99***99987 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0     0.016        48       4      43 ..     838     884 ..     835     895 .. 0.67
   2 !   28.1   0.1   7.6e-10   2.3e-06       5      55 .]     900     949 ..     896     949 .. 0.94
   3 !   27.9   0.0   8.2e-10   2.4e-06       8      55 .]     936     982 ..     936     982 .. 0.93
   4 !   24.3   0.0   1.2e-08   3.5e-05       2      43 ..     963    1003 ..     962    1005 .. 0.95
   5 !   14.4   0.0   1.4e-05     0.042       1      46 [.     995    1039 ..     995    1043 .. 0.92

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.016
       Ank_4   4 aLhyaaisgrlelvrlLlekgad........inaqdnrsGet.alhiAa 43 
                 ++ ya  +g +e+ rlLl + a+        i +  +r+G+t al   +
  EEA19030.1 838 VIVYAHRKGYTETMRLLL-HHAErtkrkddiIIEL-SRQGNTeALRVFL 884
                 7889999***********.4444333344665555.6777776665555 PP

  == domain 2  score: 28.1 bits;  conditional E-value: 7.6e-10
       Ank_4   5 LhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +  aa+++++ l+++Lle g+++n q +++G tal  Aa++ +v  ++lLl
  EEA19030.1 900 FLIAAQAEHHSLLEFLLECGVNVNLQ-DENGKTALMEAAMNRDVASAELLL 949
                 567999********************.**********************98 PP

  == domain 3  score: 27.9 bits;  conditional E-value: 8.2e-10
       Ank_4   8 aaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 aa+  ++ +++lLl+++++i+ + ++ G+tal+ Aa rg++ +++lL+
  EEA19030.1 936 AAMNRDVASAELLLSHNVSIDQR-DNFGDTALISAAERGYLPVVELLV 982
                 5667788899*************.**********************96 PP

  == domain 4  score: 24.3 bits;  conditional E-value: 1.2e-08
       Ank_4    2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAa 43  
                   taL +aa+ g l++v+lL++kgadin    ++G+tal  A+
  EEA19030.1  963 DTALISAAERGYLPVVELLVSKGADINVM-GSRGRTALMAAI 1003
                  699**************************.999*****9997 PP

  == domain 5  score: 14.4 bits;  conditional E-value: 1.4e-05
       Ank_4    1 eltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrg 46  
                  ++taL +a+  + l+lv++L + gad+  +d++ + + l+iAa+ g
  EEA19030.1  995 GRTALMAAIVRQELPLVKYLCAAGADLSITDPD-QYSVLDIAARAG 1039
                  5899*99999********************777.*********988 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       2.3   6.9e+03      13      26 ..     846     859 ..     836     888 .. 0.71
   2 !    7.7   0.1    0.0018       5.3       8      31 ..     902     926 ..     896     927 .. 0.88
   3 !   13.9   0.1   1.9e-05     0.057       1      32 []     928     960 ..     928     960 .. 0.90
   4 !   15.6   0.0   5.7e-06     0.017       2      29 ..     962     990 ..     961     992 .. 0.93
   5 !   11.3   0.0   0.00013      0.38       2      31 ..     995    1025 ..     994    1026 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 2.3
                 TTHHHHHHHHTTTS CS
         Ank  13 gkkriiklLLhGAn 26 
                 g ++  +lLLh A+
  EEA19030.1 846 GYTETMRLLLHHAE 859
                 44667777776554 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0018
                 HHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   8 lAatngkkriiklLL.hGAnlnald 31 
                 +Aa+  +++ +++LL +G n+n++d
  EEA19030.1 902 IAAQAEHHSLLEFLLeCGVNVNLQD 926
                 577899999******99******99 PP

  == domain 3  score: 13.9 bits;  conditional E-value: 1.9e-05
                 TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hGAnlnaldn 32 
                 +G T+L+ Aa+n ++  ++lLL h  +++++dn
  EEA19030.1 928 NGKTALMEAAMNRDVASAELLLsHNVSIDQRDN 960
                 7*********99988888999999999**9997 PP

  == domain 4  score: 15.6 bits;  conditional E-value: 5.7e-06
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlna 29 
                 G+T+L  Aa +g + +++lL+ +GA++n 
  EEA19030.1 962 GDTALISAAERGYLPVVELLVsKGADINV 990
                 9********99**********88****95 PP

  == domain 5  score: 11.3 bits;  conditional E-value: 0.00013
                  SBBHHHHHH...HHTTHHHHHHHH.TTTSTTCBT CS
         Ank    2 GnTPLHlAa...tngkkriiklLL.hGAnlnald 31  
                  G+T+L+ A+       +  +k+L   GA+l ++d
  EEA19030.1  995 GRTALMAAIvrqE---LPLVKYLCaAGADLSITD 1025
                  9********5554...55******88****9998 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       4.8   1.4e+04      25      39 ..     873     888 ..     872     889 .. 0.81
   2 !   27.1   0.3   1.2e-09   3.6e-06       1      53 [.     915     966 ..     915     969 .. 0.96
   3 !   15.7   0.0   4.8e-06     0.014      18      53 ..     964     999 ..     964     999 .. 0.98
   4 !   21.1   0.0   9.5e-08   0.00029       1      56 []     981    1035 ..     981    1035 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 4.8
       Ank_5  25 kygaadvvrlLl.arg 39 
                 ++g+ + +r++l +++
  EEA19030.1 873 RQGNTEALRVFLgKNN 888
                 58999******97665 PP

  == domain 2  score: 27.1 bits;  conditional E-value: 1.2e-09
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltal 53 
                 Lle+g ++vn +d++g t+L+ Aa ++    ++lLl ++++++++d+ G+tal
  EEA19030.1 915 LLECG-VNVNLQDENGKTALMEAAMNRDVASAELLLSHNVSIDQRDNFGDTAL 966
                 89***.99999999999***********************************9 PP

  == domain 3  score: 15.7 bits;  conditional E-value: 4.8e-06
       Ank_5  18 tpLhvAakygaadvvrlLlargadlnltdsrGltal 53 
                 t+L+ Aa++g+++vv+lL+  gad+n+  srG+tal
  EEA19030.1 964 TALISAAERGYLPVVELLVSKGADINVMGSRGRTAL 999
                 89********************************97 PP

  == domain 4  score: 21.1 bits;  conditional E-value: 9.5e-08
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56  
                  L+++g ad+n    +g t+L+ A+ ++ +++v++L+a gadl +td + +++ld+A
  EEA19030.1  981 LVSKG-ADINVMGSRGRTALMAAIVRQELPLVKYLCAAGADLSITDPDQYSVLDIA 1035
                  78889.55555555566**************************************9 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0         6   1.8e+04      11      26 ..     667     680 ..     666     683 .. 0.73
   2 ?   -0.9   0.1       1.4   4.1e+03       5      22 ..     805     822 ..     802     829 .. 0.83
   3 ?   -2.8   0.0       5.7   1.7e+04       5      23 ..     854     873 ..     852     884 .. 0.62
   4 !   11.1   0.2   0.00016      0.49       5      30 ..     899     923 ..     896     924 .. 0.92
   5 !   11.3   0.0   0.00015      0.44       1      30 [.     928     956 ..     928     957 .. 0.91
   6 !   12.3   0.0   6.6e-05       0.2       2      31 .]     962     990 ..     961     990 .. 0.95
   7 !   10.6   0.0   0.00025      0.74       2      30 ..     995    1022 ..     994    1023 .. 0.94
   8 ?   -1.2   0.0       1.6   4.8e+03       2      13 ..    1028    1039 ..    1027    1041 .. 0.86

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 6
       Ank_3  11 rsgnleivkfLlenkg 26 
                 ++++++ +k Lle + 
  EEA19030.1 667 EYAHIC-LKVLLE-PD 680
                 577777.999*99.55 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 1.4
       Ank_3   5 pLhlAarsgnleivkfLl 22 
                 +L + + ++ + ++++L+
  EEA19030.1 805 ALDWLVQNQFHIMLELLI 822
                 788999999999999998 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 5.7
       Ank_3   5 pLhlAarsgnle.ivkfLle 23 
                 +Lh+A r  + + i++ L +
  EEA19030.1 854 LLHHAERTKRKDdIIIELSR 873
                 56666555555446666665 PP

  == domain 4  score: 11.1 bits;  conditional E-value: 0.00016
       Ank_3   5 pLhlAarsgnleivkfLlenkgadvn 30 
                 ++ +Aa + ++++++fLle +g++vn
  EEA19030.1 899 AFLIAAQAEHHSLLEFLLE-CGVNVN 923
                 6899***************.*****9 PP

  == domain 5  score: 11.3 bits;  conditional E-value: 0.00015
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvn 30 
                 nG t+L++Aa++ +++ +++Ll  +++ ++
  EEA19030.1 928 NGKTALMEAAMNRDVASAELLLS-HNVSID 956
                 79*************88******.898876 PP

  == domain 6  score: 12.3 bits;  conditional E-value: 6.6e-05
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvna 31 
                 G t+L  Aa+ g l++v++L+  kgad+n+
  EEA19030.1 962 GDTALISAAERGYLPVVELLVS-KGADINV 990
                 89********************.9****95 PP

  == domain 7  score: 10.6 bits;  conditional E-value: 0.00025
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                  G+t+L+ A+  + l++vk+L+   gad+ 
  EEA19030.1  995 GRTALMAAIVRQELPLVKYLCA-AGADLS 1022
                  9*********************.8***87 PP

  == domain 8  score: -1.2 bits;  conditional E-value: 1.6
       Ank_3    2 GetpLhlAarsg 13  
                  +++ L +Aar+g
  EEA19030.1 1028 QYSVLDIAARAG 1039
                  7899******98 PP

>> IRK  Inward rectifier potassium channel transmembrane domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   5.3e-07    0.0016      28     111 ..     425     509 ..     419     520 .. 0.94

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 5.3e-07
         IRK  28 tlvdlkwryllllfvlsfvlsw.llfallwylialahgDleeeekeeekepCvanvksftsallfslEtqttigyGsrvvteeCp 111
                  +v+  w++ l+    + + sw  +++l  + +  a+ Dle +++e  +  C ++++   + ll    t++ i +G++  t++C 
  EEA19030.1 425 QIVEHTWKFQLVTGENVDIDSWeAILGLYVWSLKQANRDLEGNRNEFFRAFCPKDITPHQARLLHRTWTNNRIIFGKNLSTTRCF 509
                 689*******************66899*********************************************************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1062 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       689  (0.0384294); expected 358.6 (0.02)
Passed bias filter:                      534  (0.0297841); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.79u 0.29s 00:00:01.08 Elapsed: 00:00:00.45
# Mc/sec: 7116.12
//
Query:       EEA19031.1  [L=1040]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.5e-25   87.8   3.9      2e-16   60.3   0.4    3.9  3  Ank_2     Ankyrin repeats (3 copies)
    8.1e-21   74.1   1.6    2.2e-06   28.1   0.1    5.3  5  Ank_4     Ankyrin repeats (many copies)
      2e-14   53.3   2.3      0.017   15.6   0.0    5.3  5  Ank       Ankyrin repeat
      2e-14   53.4   1.6    3.5e-06   27.2   0.3    4.0  4  Ank_5     Ankyrin repeats (many copies)
    9.9e-14   50.1   5.6       0.19   12.4   0.0    6.9  8  Ank_3     Ankyrin repeat
    0.00066   19.5   0.0     0.0015   18.3   0.0    1.5  1  IRK       Inward rectifier potassium channel transmembrane do


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.4   0.1   0.00054       1.6      12      74 ..     795     863 ..     782     872 .. 0.65
   2 !   60.3   0.4   6.8e-20     2e-16       2      81 ..     879     968 ..     878     970 .. 0.91
   3 !   15.9   0.0   4.8e-06     0.014      52      83 .]     972    1003 ..     969    1003 .. 0.93

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00054
       Ank_2  12 lvklLl.egadpn..k..ngktaLhyAakngnleivklLleh..adndgrtpLhyAarsghleivklLle 74 
                 +++lL+ + ++ +  +    + ++ yA ++g++e+++lLl h   ++    +++  +r+g++e+++++l 
  EEA19031.1 795 MLELLIiKMVN-DlaEmyRLLAVIVYAHRKGYTETMRLLLHHaeRTKRKDDIIIELSRQGNTEALRVFLG 863
                 55555543322.23224233455669**************885533556678888888999999998883 PP

  == domain 2  score: 60.3 bits;  conditional E-value: 6.8e-20
       Ank_2   2 hlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinl 81 
                  +Aa+ ++++l+++Ll +g+++n  + ngktaL+ Aa+n ++  ++lLl+h       dn g t+L+ Aa+ g+l +v+lL+ kgadin+
  EEA19031.1 879 LIAAQAEHHSLLEFLLeCGVNVNlqDeNGKTALMEAAMNRDVASAELLLSHnvsidqRDNFGDTALISAAERGYLPVVELLVSKGADINV 968
                 5899999899*******9999999538*************88889*****99996655599*********************99****97 PP

  == domain 3  score: 15.9 bits;  conditional E-value: 4.8e-06
       Ank_2   52 dgrtpLhyAarsghleivklLlekgadinlkd 83  
                   grt+L++A+  + l +vk+L+  gad+ ++d
  EEA19031.1  972 RGRTALMAAIVRQELPLVKYLCAAGADLSITD 1003
                  69********************99***99987 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0     0.016        47       4      43 ..     816     862 ..     813     873 .. 0.67
   2 !   28.1   0.1   7.4e-10   2.2e-06       5      55 .]     878     927 ..     874     927 .. 0.94
   3 !   28.0   0.0     8e-10   2.4e-06       8      55 .]     914     960 ..     914     960 .. 0.93
   4 !   24.3   0.0   1.1e-08   3.4e-05       2      43 ..     941     981 ..     940     983 .. 0.95
   5 !   14.5   0.0   1.4e-05     0.041       1      46 [.     973    1017 ..     973    1021 .. 0.92

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.016
       Ank_4   4 aLhyaaisgrlelvrlLlekgad........inaqdnrsGet.alhiAa 43 
                 ++ ya  +g +e+ rlLl + a+        i +  +r+G+t al   +
  EEA19031.1 816 VIVYAHRKGYTETMRLLL-HHAErtkrkddiIIEL-SRQGNTeALRVFL 862
                 7889999***********.4444333344665555.6777776665555 PP

  == domain 2  score: 28.1 bits;  conditional E-value: 7.4e-10
       Ank_4   5 LhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +  aa+++++ l+++Lle g+++n q +++G tal  Aa++ +v  ++lLl
  EEA19031.1 878 FLIAAQAEHHSLLEFLLECGVNVNLQ-DENGKTALMEAAMNRDVASAELLL 927
                 567999********************.**********************98 PP

  == domain 3  score: 28.0 bits;  conditional E-value: 8e-10
       Ank_4   8 aaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 aa+  ++ +++lLl+++++i+ + ++ G+tal+ Aa rg++ +++lL+
  EEA19031.1 914 AAMNRDVASAELLLSHNVSIDQR-DNFGDTALISAAERGYLPVVELLV 960
                 5667788899*************.**********************96 PP

  == domain 4  score: 24.3 bits;  conditional E-value: 1.1e-08
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAa 43 
                  taL +aa+ g l++v+lL++kgadin    ++G+tal  A+
  EEA19031.1 941 DTALISAAERGYLPVVELLVSKGADINVM-GSRGRTALMAAI 981
                 699**************************.999*****9997 PP

  == domain 5  score: 14.5 bits;  conditional E-value: 1.4e-05
       Ank_4    1 eltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrg 46  
                  ++taL +a+  + l+lv++L + gad+  +d++ + + l+iAa+ g
  EEA19031.1  973 GRTALMAAIVRQELPLVKYLCAAGADLSITDPD-QYSVLDIAARAG 1017
                  5899*99999********************777.*********988 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       2.3   6.8e+03      13      26 ..     824     837 ..     814     866 .. 0.71
   2 !    7.7   0.1    0.0017       5.2       8      31 ..     880     904 ..     874     905 .. 0.88
   3 !   13.9   0.1   1.9e-05     0.056       1      32 []     906     938 ..     906     938 .. 0.90
   4 !   15.6   0.0   5.5e-06     0.017       2      29 ..     940     968 ..     939     970 .. 0.93
   5 !   11.3   0.0   0.00013      0.37       2      31 ..     973    1003 ..     972    1004 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 2.3
                 TTHHHHHHHHTTTS CS
         Ank  13 gkkriiklLLhGAn 26 
                 g ++  +lLLh A+
  EEA19031.1 824 GYTETMRLLLHHAE 837
                 44667777776554 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0017
                 HHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   8 lAatngkkriiklLL.hGAnlnald 31 
                 +Aa+  +++ +++LL +G n+n++d
  EEA19031.1 880 IAAQAEHHSLLEFLLeCGVNVNLQD 904
                 577899999******99******99 PP

  == domain 3  score: 13.9 bits;  conditional E-value: 1.9e-05
                 TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hGAnlnaldn 32 
                 +G T+L+ Aa+n ++  ++lLL h  +++++dn
  EEA19031.1 906 NGKTALMEAAMNRDVASAELLLsHNVSIDQRDN 938
                 7*********99988888999999999**9997 PP

  == domain 4  score: 15.6 bits;  conditional E-value: 5.5e-06
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlna 29 
                 G+T+L  Aa +g + +++lL+ +GA++n 
  EEA19031.1 940 GDTALISAAERGYLPVVELLVsKGADINV 968
                 9********99**********88****95 PP

  == domain 5  score: 11.3 bits;  conditional E-value: 0.00013
                  SBBHHHHHH...HHTTHHHHHHHH.TTTSTTCBT CS
         Ank    2 GnTPLHlAa...tngkkriiklLL.hGAnlnald 31  
                  G+T+L+ A+       +  +k+L   GA+l ++d
  EEA19031.1  973 GRTALMAAIvrqE---LPLVKYLCaAGADLSITD 1003
                  9********5554...55******88****9998 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       4.7   1.4e+04      25      39 ..     851     866 ..     850     867 .. 0.81
   2 !   27.2   0.3   1.2e-09   3.5e-06       1      53 [.     893     944 ..     893     947 .. 0.96
   3 !   15.7   0.0   4.7e-06     0.014      18      53 ..     942     977 ..     942     977 .. 0.98
   4 !   21.1   0.0   9.3e-08   0.00028       1      56 []     959    1013 ..     959    1013 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 4.7
       Ank_5  25 kygaadvvrlLl.arg 39 
                 ++g+ + +r++l +++
  EEA19031.1 851 RQGNTEALRVFLgKNN 866
                 58999******97665 PP

  == domain 2  score: 27.2 bits;  conditional E-value: 1.2e-09
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltal 53 
                 Lle+g ++vn +d++g t+L+ Aa ++    ++lLl ++++++++d+ G+tal
  EEA19031.1 893 LLECG-VNVNLQDENGKTALMEAAMNRDVASAELLLSHNVSIDQRDNFGDTAL 944
                 89***.99999999999***********************************9 PP

  == domain 3  score: 15.7 bits;  conditional E-value: 4.7e-06
       Ank_5  18 tpLhvAakygaadvvrlLlargadlnltdsrGltal 53 
                 t+L+ Aa++g+++vv+lL+  gad+n+  srG+tal
  EEA19031.1 942 TALISAAERGYLPVVELLVSKGADINVMGSRGRTAL 977
                 89********************************97 PP

  == domain 4  score: 21.1 bits;  conditional E-value: 9.3e-08
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56  
                  L+++g ad+n    +g t+L+ A+ ++ +++v++L+a gadl +td + +++ld+A
  EEA19031.1  959 LVSKG-ADINVMGSRGRTALMAAIVRQELPLVKYLCAAGADLSITDPDQYSVLDIA 1013
                  78889.55555555566**************************************9 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0         6   1.8e+04      11      26 ..     645     658 ..     644     661 .. 0.73
   2 ?   -0.9   0.1       1.3     4e+03       5      22 ..     783     800 ..     780     807 .. 0.83
   3 ?   -2.7   0.0       5.3   1.6e+04       5      23 ..     832     851 ..     830     863 .. 0.60
   4 !   11.2   0.2   0.00016      0.48       5      30 ..     877     901 ..     874     902 .. 0.92
   5 !   11.3   0.0   0.00014      0.43       1      30 [.     906     934 ..     906     935 .. 0.91
   6 !   12.4   0.0   6.4e-05      0.19       2      31 .]     940     968 ..     939     968 .. 0.95
   7 !   10.6   0.0   0.00024      0.73       2      30 ..     973    1000 ..     972    1001 .. 0.94
   8 ?   -1.1   0.0       1.6   4.7e+03       2      13 ..    1006    1017 ..    1005    1019 .. 0.86

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 6
       Ank_3  11 rsgnleivkfLlenkg 26 
                 ++++++ +k Lle + 
  EEA19031.1 645 EYAHIC-LKVLLE-PD 658
                 577777.999*99.55 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 1.3
       Ank_3   5 pLhlAarsgnleivkfLl 22 
                 +L + + ++ + ++++L+
  EEA19031.1 783 ALDWLVQNQFHIMLELLI 800
                 788999999999999998 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 5.3
       Ank_3   5 pLhlAarsgnle.ivkfLle 23 
                 +Lh+A r  + + i++ L +
  EEA19031.1 832 LLHHAERTKRKDdIIIELSR 851
                 56666444444446666655 PP

  == domain 4  score: 11.2 bits;  conditional E-value: 0.00016
       Ank_3   5 pLhlAarsgnleivkfLlenkgadvn 30 
                 ++ +Aa + ++++++fLle +g++vn
  EEA19031.1 877 AFLIAAQAEHHSLLEFLLE-CGVNVN 901
                 6899***************.*****9 PP

  == domain 5  score: 11.3 bits;  conditional E-value: 0.00014
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvn 30 
                 nG t+L++Aa++ +++ +++Ll  +++ ++
  EEA19031.1 906 NGKTALMEAAMNRDVASAELLLS-HNVSID 934
                 79*************88******.898876 PP

  == domain 6  score: 12.4 bits;  conditional E-value: 6.4e-05
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvna 31 
                 G t+L  Aa+ g l++v++L+  kgad+n+
  EEA19031.1 940 GDTALISAAERGYLPVVELLVS-KGADINV 968
                 89********************.9****95 PP

  == domain 7  score: 10.6 bits;  conditional E-value: 0.00024
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                  G+t+L+ A+  + l++vk+L+   gad+ 
  EEA19031.1  973 GRTALMAAIVRQELPLVKYLCA-AGADLS 1000
                  9*********************.8***87 PP

  == domain 8  score: -1.1 bits;  conditional E-value: 1.6
       Ank_3    2 GetpLhlAarsg 13  
                  +++ L +Aar+g
  EEA19031.1 1006 QYSVLDIAARAG 1017
                  7899******98 PP

>> IRK  Inward rectifier potassium channel transmembrane domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   5.1e-07    0.0015      28     111 ..     403     487 ..     397     498 .. 0.94

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 5.1e-07
         IRK  28 tlvdlkwryllllfvlsfvlsw.llfallwylialahgDleeeekeeekepCvanvksftsallfslEtqttigyGsrvvteeCp 111
                  +v+  w++ l+    + + sw  +++l  + +  a+ Dle +++e  +  C ++++   + ll    t++ i +G++  t++C 
  EEA19031.1 403 QIVEHTWKFQLVTGENVDIDSWeAILGLYVWSLKQANRDLEGNRNEFFRAFCPKDITPHQARLLHRTWTNNRIIFGKNLSTTRCF 487
                 689*******************66899*********************************************************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1040 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       636  (0.0354733); expected 358.6 (0.02)
Passed bias filter:                      531  (0.0296168); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.84u 0.28s 00:00:01.12 Elapsed: 00:00:00.49
# Mc/sec: 6341.19
//
Query:       EEA19032.1  [L=379]
Description: DUF124 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      7e-49  166.4   0.1      1e-48  165.9   0.1    1.2  1  AIM24     Mitochondrial biogenesis AIM24


Domain annotation for each model (and alignments):
>> AIM24  Mitochondrial biogenesis AIM24
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  165.9   0.1   5.5e-53     1e-48       2     201 .]     165     363 ..     164     363 .. 0.95

  Alignments for each domain:
  == domain 1  score: 165.9 bits;  conditional E-value: 5.5e-53
                 EEESS.SS-EEEEEE-TT-EEEE-CCGEEEEETTEEEEE--------------EEEEEEES.SS-EEEEE--SSSEEEEEEEG.GTT.EEEEEGGGEEE CS
       AIM24   2 evlge.pssllsvtLspgeelyaerGalvamsgkvemetgllkalkrlltgeslfllkftakissgtvllapklpgtivtlel.gggdwlivqkdafLA 98 
                 +++++   s+++ +L+ g +l a++G ++ams++v++++++  ++k+ll g  +  +++t+   +g+vllap+++g+i+ l+l + g+++ v++da+LA
  EEA19032.1 165 RISHRsVNSIVTFQLAMGAPLEARPGVMIAMSPTVTLKGSFHFSMKKLLIGGEMAHSTYTG---PGEVLLAPSVLGDITILRLtDDGETWKVGRDAYLA 260
                 67777789***************************************7777779******5...5***********999999978999*********** PP

                 EETT-EEEEEEEE--.SSGGGTS-EEEEEEESSSEEEEEEECSEEEEEEE.EEEEEEEGGGEEEEETTEEEEEEEE..TT---STTTTS-EEEEEEEEE CS
       AIM24  99 atgnveldikfqkgl.kglfggeglflqkltGrGlvalsgyGaiyeielkageelvvdpghlvafsgslkfdierv..gglkrrligGeglflkltGpg 194
                  t +v+ + k q +l k+lf+geg f++ +tG Glv+++++Ga+++++l +ge+++vd+ghlva++  +++ ierv  gg++++l +Gegl ++++Gpg
  EEA19032.1 261 NTTSVKKKYKAQ-NLsKTLFSGEGWFVYNITGPGLVWMQSFGAVIRKDLVEGESYFVDNGHLVAWN--CEYGIERVasGGVISSLSSGEGLACRFKGPG 356
                 ************.788999**********************************************9..99****99999******************** PP

                 EEEEESS CS
       AIM24 195 tvllqsr 201
                 tv+lq+r
  EEA19032.1 357 TVYLQTR 363
                 *****98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (379 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       428  (0.0238719); expected 358.6 (0.02)
Passed bias filter:                      261  (0.0145574); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.45
# Mc/sec: 2541.32
//
Query:       EEA19033.1  [L=307]
Description: translational initiation factor 2 beta [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.5e-41  138.5   0.1    1.4e-40  137.8   0.1    1.3  1  eIF-5_eIF-2B     Domain found in IF2B/IF5
  ------ inclusion threshold ------
       0.22   11.1   1.8       0.51    9.9   1.8    1.6  1  TF_Zn_Ribbon     TFIIB zinc-binding
       0.23   11.1   4.6        0.3   10.7   4.6    1.1  1  GET2             GET complex subunit GET2
       0.26   10.8   2.4       0.48   10.0   2.4    1.3  1  Peptidase_M13    Peptidase family M13
        1.6    9.1   7.6        1.2    9.5   0.4    2.6  2  Arc_trans_TRASH  Archaeal TRASH domain
        4.6    7.1   6.9         23    4.8   4.0    2.7  3  zf-HYPF          HypF finger


Domain annotation for each model (and alignments):
>> eIF-5_eIF-2B  Domain found in IF2B/IF5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.8   0.1   4.6e-44   1.4e-40       8     116 ..     176     285 ..     170     286 .. 0.97

  Alignments for each domain:
  == domain 1  score: 137.8 bits;  conditional E-value: 4.6e-44
                   SS--SSTT--EEEETT.EEEETTHHHHHHHHTTSHHHHHHHHHHHHTSEEEESETTEEEESSSSSCCHHHHHHHHHHHHHTSTSSSTSTCEEECC.S CS
  eIF-5_eIF-2B   8 kerykmpklqvkvegkkktvivNfeeiakaLnrdpehvlkyllkelgtqgsidengrlilngkfeakkleklldkyieeyVlCkeCkspetelek.e 103
                   ++ y++p++q+ +eg+++t+++N+++i+k+++r+++hv+++l++elgt+gs+d+++rl+++g+f++k++e++l++yi eyV+Ck+C+sp+tel+k e
    EEA19033.1 176 SKSYRIPPPQCLREGNRRTIFANIADICKRMKRSDDHVMQFLFAELGTSGSVDGSRRLVIKGRFQQKQIENVLRRYIVEYVTCKTCRSPDTELNKgE 272
                   46799******************************************************************************************99 PP

                   SSCEEEEESSSTC CS
  eIF-5_eIF-2B 104 erllvlkCkaCga 116
                   +rl++++C++Cg+
    EEA19033.1 273 NRLYFVTCNSCGS 285
                   ************8 PP

>> TF_Zn_Ribbon  TFIIB zinc-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   1.8   0.00017      0.51       2      27 ..     257     285 ..     256     295 .. 0.91

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00017
                   EETTTTCEECHEE..TSTTCE.EESSSSB CS
  TF_Zn_Ribbon   2 kCPnCgstnlveD..pergel.vCtdCGl 27 
                   +C+ C s++++++  ++r  + +C +CG+
    EEA19033.1 257 TCKTCRSPDTELNkgENRLYFvTCNSCGS 285
                   7************999999999******7 PP

>> GET2  GET complex subunit GET2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   4.6    0.0001       0.3      62     165 ..      11     113 ..       1     131 [. 0.51

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.0001
        GET2  62 sssssasehddpeiediseiavkpkktasskkksplseesepeapqldqllkqllqqqqqgnsen.sqdaesstP..d.lfsqllkmmkqgegg.saks 155
                 + +s a   d+  ++d +  +++    ++++++s+    +++e  ++ +l+k+l ++++ ++s++ + +++++ P  d +++  l+ mk+++++ ++ +
  EEA19033.1  11 HRKSVAF-SDEATVMDANGEVTEATPVERETAESH---STDKEVDEVTELFKGLSKKKKTKKSKDaDAEGDEAAPagDgELD--LSAMKKKKKKaKKAD 103
                 2222222.344577776655544444433333333...22445558999999999886655554414555666776633444..455554444422244 PP

        GET2 156 eeetssspee 165
                   +++++ +e
  EEA19033.1 104 VGDFEAKLAE 113
                 4444444444 PP

>> Peptidase_M13  Peptidase family M13
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   2.4   0.00016      0.48      41     134 ..       6     108 ..       2     113 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00016
  Peptidase_M13  41 aHEltH....gfddqgvqfdkegnla....swltdedaeefkekakclieqfsevtepektkavngaltlgEniADlggleiAyraykk.lksake 127
                     HE+ H    +f d+   +d +g+++       ++ +++   ++  ++ e f+++ +++ktk+ ++a   g+++A  g  e  + a kk +k+ak+
     EEA19033.1   6 VHETKHrksvAFSDEATVMDANGEVTeatpVERETAESHSTDKEVDEVTELFKGLSKKKKTKKSKDADAEGDEAAPAGDGELDLSAMKKkKKKAKK 101
                    58888866668***************55554456777888899999*****************************************996677777 PP

  Peptidase_M13 128 erlpele 134
                      + ++e
     EEA19033.1 102 ADVGDFE 108
                    7777777 PP

>> Arc_trans_TRASH  Archaeal TRASH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   1.9     0.079   2.4e+02      23      31 ..     255     263 ..     248     270 .. 0.85
   2 ?    9.5   0.4    0.0004       1.2      16      30 ..     270     284 ..     265     286 .. 0.86

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.079
  Arc_trans_TRASH  23 yvCCktCks 31 
                      yv CktC+s
       EEA19033.1 255 YVTCKTCRS 263
                      899****86 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.0004
  Arc_trans_TRASH  16 klknkvYyvCCktCk 30 
                      k  n+ Y+v C++C 
       EEA19033.1 270 KGENRLYFVTCNSCG 284
                      668***********6 PP

>> zf-HYPF  HypF finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.1       1.5   4.6e+03       3       8 ..     184     189 ..     184     193 .. 0.77
   2 ?    4.5   0.2    0.0099        30      15      27 ..     249     261 ..     241     264 .. 0.83
   3 ?    4.8   4.0    0.0078        23       2      30 ..     258     286 ..     257     290 .. 0.77

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 1.5
                 HHHHHH CS
     zf-HYPF   3 edClrE 8  
                 ++ClrE
  EEA19033.1 184 PQCLRE 189
                 689998 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.0099
                 TTTT-TT---TTT CS
     zf-HYPF  15 RRfhaqfisCtnC 27 
                 RR+  + ++C+ C
  EEA19033.1 249 RRYIVEYVTCKTC 261
                 ************9 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.0078
                 -HHHHH...HHC-TTSTTTT-TT---TTTS-- CS
     zf-HYPF   2 CedClr...EykdpldRRfhaqfisCtnCGPr 30 
                 C+ C+    E++  ++R +   f++C++CG r
  EEA19033.1 258 CKTCRSpdtELNKGENRLY---FVTCNSCGSR 286
                 8888766669999999999...7888888887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (307 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1265  (0.0705561); expected 358.6 (0.02)
Passed bias filter:                      680  (0.0379274); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 2059.49
//
Query:       EEA19034.1  [L=129]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.021   14.7   0.2      0.027   14.4   0.2    1.2  1  LAT2      Linker for activation of T-cells family member 2


Domain annotation for each model (and alignments):
>> LAT2  Linker for activation of T-cells family member 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.2   1.5e-06     0.027     111     152 ..      33      74 ..      14      84 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.5e-06
        LAT2 111 snsYenvlickpketesedeeseDYqnsasieqWreskrvve 152
                 + s e+ + + p+et  e +   DYq+s + eqWres   +e
  EEA19034.1  33 TSSDEDEITSLPSETSTESDFLSDYQDSDAEEQWRESLEQLE 74 
                 677777788889999999999****************76665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (129 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       760  (0.0423894); expected 358.6 (0.02)
Passed bias filter:                      529  (0.0295053); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.23s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 909.52
//
Query:       EEA19035.1  [L=350]
Description: hypothetical protein PMAA_013020 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.07   13.3   6.8       0.11   12.6   6.8    1.3  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   6.8   6.4e-06      0.11       2      14 ..     163     175 ..     162     179 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 6.4e-06
                 S-HHHHHCT---S CS
     Zn_clus   2 aCdnCrkkKvKCd 14 
                 aCdnCr++K KC 
  EEA19035.1 163 ACDNCRRRKKKCY 175
                 9***********5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (350 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       437  (0.0243739); expected 358.6 (0.02)
Passed bias filter:                      277  (0.0154498); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2616.00
//
Query:       EEA19036.1  [L=196]
Description: hypothetical protein PMAA_013030 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.68   10.2   2.6        2.2    8.6   0.3    2.2  2  DUF2149   Uncharacterized conserved protein (DUF2149)


Domain annotation for each model (and alignments):
>> DUF2149  Uncharacterized conserved protein (DUF2149)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.3   0.00012       2.2      30      78 ..       7      55 ..       1      66 [. 0.82
   2 ?    1.6   0.1     0.018   3.3e+02      49      81 ..     164     196 .]     139     196 .] 0.61

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00012
     DUF2149 30 ellsseedvtvvkkpgkekmeiivkegeelkkakesaekasgkGerlGt 78
                + ls++e++   ++p+++++ei+  ++ ++ + ++ ++  s++G + G+
  EEA19036.1  7 KALSDQEEFYSREQPKQKRVEIVQSHAVNVIHEEQVQKYFSQRGMEEGH 55
                566779****************998888887788888899999999987 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.018
     DUF2149  49 meiivkegeelkkakesaekasgkG.erlGtayr 81 
                 +ei  +   ++   k++ e ++ kG +r G +y+
  EEA19036.1 164 VEIRAH-QAQVLVDKTTREGQTAKGsTRDGFVYK 196
                 344222.333334566666777788899999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (196 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       582  (0.0324614); expected 358.6 (0.02)
Passed bias filter:                      427  (0.0238162); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.25s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1347.99
//
Query:       EEA19037.1  [L=430]
Description: hypothetical protein PMAA_013040 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (430 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       358  (0.0199677); expected 358.6 (0.02)
Passed bias filter:                      251  (0.0139997); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.47u 0.23s 00:00:00.70 Elapsed: 00:00:00.39
# Mc/sec: 3276.38
//
Query:       EEA19038.1  [L=135]
Description: glycine-rich RNA-binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-21   75.8   0.0    2.2e-21   75.4   0.0    1.1  1  RRM_1     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom
     0.0038   17.3   0.0     0.0055   16.8   0.0    1.4  1  RRM_7     RNA recognition motif
  ------ inclusion threshold ------
      0.082   13.6  25.0       0.12   13.1  25.0    1.4  1  GRP       Glycine rich protein family


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.4   0.0   3.7e-25   2.2e-21       1      70 []       4      74 ..       4      74 .. 0.99

  Alignments for each domain:
  == domain 1  score: 75.4 bits;  conditional E-value: 3.7e-25
                EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEEE CS
       RRM_1  1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrelk 70
                lf+g+L++ +t+++L+  F+kfG i+++ +++d  t++s+gf+fV+F +  +A++A+e +n++ ++gr+++
  EEA19038.1  4 LFIGGLAWHTTDDTLRSGFEKFGTIEEAIVIKDrDTNRSRGFGFVRFSTDAEADAAIEGMNNQDFDGRVIR 74
                8*******************************************************************996 PP

>> RRM_7  RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.0   9.2e-07    0.0055       2      29 ..       2      29 ..       1      69 [. 0.80

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 9.2e-07
       RRM_7  2 rkvFvGGlPiDiteeelkatfkefgkvl 29
                 k+F+GGl +  t++ l + f++fg++ 
  EEA19038.1  2 AKLFIGGLAWHTTDDTLRSGFEKFGTIE 29
                59***********************875 PP

>> GRP  Glycine rich protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1  25.0     2e-05      0.12      40      93 ..      75     126 ..      48     133 .. 0.75

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2e-05
         GRP  40 vkdekyggggkhggGgygggggggngGGGykgggGgygggggggeggyGgGygg 93 
                 v+ +++  + ++++Gg++g gg++   GG  + +Ggy ggg+gg+gg GgG + 
  EEA19038.1  75 VDRASNNASSRGNEGGFHGRGGYNRFEGG--NNRGGYSGGGYGGHGGWGGGNQY 126
                 45555555566699********9999999..45678999999999999999654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (135 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       277  (0.0154498); expected 358.6 (0.02)
Passed bias filter:                      182  (0.0101512); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.37u 0.26s 00:00:00.63 Elapsed: 00:00:00.41
# Mc/sec: 997.42
//
Query:       EEA19039.1  [L=269]
Description: cation transport protein ChaC, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-52  178.7   0.0    1.4e-52  178.4   0.0    1.1  1  ChaC      ChaC-like protein


Domain annotation for each model (and alignments):
>> ChaC  ChaC-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  178.4   0.0   7.7e-57   1.4e-52       1     177 [.      21     231 ..      21     233 .. 0.92

  Alignments for each domain:
  == domain 1  score: 178.4 bits;  conditional E-value: 7.7e-57
                 EEEEESSHHHHS--TT-SEEEEEEEETEEEEEEEEESSSSS-SSS-EEEEEEEEHHH.................-EEEEEEEEE-GGGGGGGGGGGGGS CS
        ChaC   1 lwvfgYGSLiwkpdfeytesrravihgyaRrfwlsstdhRGteekPGrvltLiedee.................gstiGvvyripaeeaeevleyLeeR 82 
                 lwvfgYGSLiwkp+ +++++++++i gy+Rrfw+ stdhRGt+e+PGrv+t ie+                   ++++G +y+ipa++aeev +yL++R
  EEA19039.1  21 LWVFGYGSLIWKPPPHFDKRVPGYISGYVRRFWQASTDHRGTPERPGRVVTVIEK-SfwetlddphktlessnsSTVWGAAYHIPASHAEEVHDYLDVR 118
                 7*****************************************************7.4599*************99************************ PP

                 TT..TTEEEEEEEEEE...................-EETTTS-EEEEEEEEEE-TTSTTB--S-...-HHHHHHHHHH-EETTEEHHHHHHHHHHHHHT CS
        ChaC  83 ElvtnGytlkevevyl...................kkdakeekvvlealvyvatikneqyagde...dleeiAkviaaaaGpsGsnaeYlfelakalek 159
                 E+  +Gyt++ +++y+                      ++++++  +++vy++++ n+q++ d    + +++A+vi++ +G+sG+n eYl+ l+kale 
  EEA19039.1 119 EI--DGYTVHYTPFYAvrpkdeqppsqhqqsplseLLPTSSKPI--TCMVYIGQPTNPQFLRDPaerHPASVAEVISRGVGQSGRNPEYLYLLEKALEG 213
                 *8..9**********************99999975334455555..**************9765222556899************************** PP

                 S-----BHHHHHHHHHHH CS
        ChaC 160 lgigirDehLeeleelvk 177
                 lg+g +D h+++l++ vk
  EEA19039.1 214 LGLGLADGHVTDLVRRVK 231
                 ***************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (269 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       298  (0.0166211); expected 358.6 (0.02)
Passed bias filter:                      250  (0.0139439); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.25s 00:00:00.63 Elapsed: 00:00:00.38
# Mc/sec: 2100.02
//
Query:       EEA19040.1  [L=351]
Description: short-chain dehydrogenase/reductase family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.5e-21   76.7   0.2    9.8e-20   70.8   0.1    2.2  2  adh_short        short chain dehydrogenase
    5.7e-14   52.2   0.1    4.8e-12   45.9   0.0    2.1  2  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
      1e-08   35.3   0.2    1.7e-08   34.6   0.2    1.4  1  KR               KR domain
  ------ inclusion threshold ------
      0.033   13.3   0.0      0.049   12.8   0.0    1.3  1  Polysacc_synt_2  Polysaccharide biosynthesis protein


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.8   0.1   2.2e-23   9.8e-20       1     132 [.      26     161 ..      26     173 .. 0.93
   2 !    3.8   0.0    0.0078        35     148     190 ..     216     262 ..     209     266 .. 0.83

  Alignments for each domain:
  == domain 1  score: 70.8 bits;  conditional E-value: 2.2e-23
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHT.TSE...EEEEE-TTTSHHHHHHHHHHHHHHH..SSESEEEE---SS--SS CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvv.vdrseekleevakelkee.gak...alaiqvDvtdreevealvekavkkl..gkldvLvnNAGitgsgp 92 
                 k++++tGa+sG+G + + +++++G++ ++  +r  ++ +++++el++  g +   ++++++D+++ ++v ++ +++ ++l   kldv+v NAGi  ++ 
  EEA19040.1  26 KTIVITGATSGLGFEASLKFLQQGVSSLIiSSRDHARGQQAKNELESRaG-RvgvVTVLPLDMSSFQSVVEFASRVNSELngRKLDVVVLNAGI--MHR 121
                 79***********************999979999************9962.434488999********************9999**********..788 PP

                 GGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEE CS
   adh_short  93 fselseeewervievNltgvflltravlpamlkqssGrIv 132
                    l+e+ we++++vN  ++ ll+ ++lp++ +qs+ ++v
  EEA19040.1 122 DYTLTEDGWEDTLQVNTLSTALLAGLLLPTLQQQSNNEVV 161
                 88999999************************99998888 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.0078
                 HHHHHHHHHHHHHHHHHHHHGGGT....EEEEEEEESSBSSHHHHHH CS
   adh_short 148 aYsAsKaavagltrslakelaptg....irvnavaPGlvdTdmakel 190
                  Y  sK +++  +r++a++  + +    + +n+v PGl+++++ ++ 
  EEA19040.1 216 KYEISKLFLEYTSRCMAEQTINPNgslnVIINTVKPGLCASALGRQY 262
                 6888999999999999998766555888***********99887765 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.9   0.0   1.1e-15   4.8e-12       1     124 [.      32     161 ..      32     181 .. 0.84
   2 !    4.3   0.0    0.0057        26     139     195 ..     215     273 ..     204     292 .. 0.74

  Alignments for each domain:
  == domain 1  score: 45.9 bits;  conditional E-value: 1.1e-15
                   TTTTSHHHHHHHHHHHTT-E.EEEEESSGGH.HHHHHHHHHHTTSE.E...EE--TTSHHHHHHHHHHHHHHH..SSEEEEEE-----EGCSS-GGG CS
  adh_short_C2   1 GaasgIGraiAkalaeeGae.vvltdlneea.kkrveelaeelgae.v...lecDVtdeeqvealveevvekf..gklDilvnnagiapklkgpfle 89 
                   Ga sg+G+++  ++ ++G + ++++ ++ ++ +++ +el+++ g+  v   l++D ++ ++v +++++v +++   klD++v nagi+++      +
    EEA19040.1  32 GATSGLGFEASLKFLQQGVSsLIISSRDHARgQQAKNELESRAGRVgVvtvLPLDMSSFQSVVEFASRVNSELngRKLDVVVLNAGIMHR----DYT 124
                   999***************975888888888877777888888774442356**********************9899************9....467 PP

                   H-HHHHHHHHHHHTHHHHHHHHHHHHHCTSC..CEEE CS
  adh_short_C2  90 tsreefdraldvnlyslfllakaalplmkeg..gsiv 124
                   +++++++++l+vn+ s++lla  +lp ++++    +v
    EEA19040.1 125 LTEDGWEDTLQVNTLSTALLAGLLLPTLQQQsnNEVV 161
                   89************************88887444444 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.0057
                   THHHHHHHHHHHHHHHHHHHH....GGGTEEEEEEEE--BHCTGGGGSTTHHHHHHHHHHH CS
  adh_short_C2 139 naygaaKaalealtrylAvel....gpkgiRvNavspgpikTlaasgikgfdelleelear 195
                   + y ++K  le ++r++A +     g+ ++ +N+v pg+ +  + ++++   + +e+++a 
    EEA19040.1 215 QKYEISKLFLEYTSRCMAEQTinpnGSLNVIINTVKPGLCASALGRQYT--AHWYERWAAG 273
                   5799**************9973333557899999999999988877765..5666666555 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.6   0.2   3.8e-12   1.7e-08       2     108 ..      27     133 ..      26     183 .. 0.82

  Alignments for each domain:
  == domain 1  score: 34.6 bits;  conditional E-value: 3.8e-12
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHS..S---EEEE--------.-T CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaee..ppikGvihaAgvlrdk.ll 97 
                 t +itG++ gLG e +   +++g ++l++ sR++a  +++k+++++ + +   v+v+++D s+ ++v +  +++++e   +++  v+  Ag+++ + +l
  EEA19040.1  27 TIVITGATSGLGFEASLKFLQQGVSSLIISSRDHARGQQAKNELESRAGRVGVVTVLPLDMSSFQSVVEFASRVNSELngRKLDVVVLNAGIMHRDyTL 125
                 679******************************888888887777777777789********************9998889**********99855044 PP

                 TT--HHHHHHH CS
          KR  98 eemtaedleqv 108
                 +e   ed    
  EEA19040.1 126 TEDGWED---T 133
                 4433333...3 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   1.1e-05     0.049       1     111 [.      28     144 ..      28     180 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.1e-05
                      EEEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH......-TTEEE....E....E--TT-HHHHHHHTT..T-SEEEE------. CS
  Polysacc_synt_2   1 vlvtGagGsiGselvrqilkkkpkkiillerdElklyeiekeleeelkkkklkv....eivpvigdvrdkerlekaleelkvdvvfhaAAlKh. 89 
                      +++tGa+  +G e   ++l++ ++++i+ +rd  + ++ ++ele+++ +  + +    ++ ++   v+ ++r+++ l+  k dvv+  A + h 
       EEA19040.1  28 IVITGATSGLGFEASLKFLQQGVSSLIISSRDHARGQQAKNELESRAGRVGVVTvlplDMSSFQSVVEFASRVNSELNGRKLDVVVLNAGIMHr 121
                      79****************************************9877766555220000223333345557888999999999999888877662 PP

                      .HHHHHHSHHHHHHHHHHHHHHH CS
  Polysacc_synt_2  90 .VPlveenpleaiktNvlgtenv 111
                         l e  + ++++ N l+t  +
       EEA19040.1 122 dYTLTEDGWEDTLQVNTLSTALL 144
                      24577888888888888888665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (351 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       432  (0.024095); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2577.46
//
Query:       EEA19041.1  [L=315]
Description: calcium binding modulator protein (Alg2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    5.6e-20   69.5   3.7    1.6e-06   27.6   0.1    4.4  4  EF-hand_6  EF-hand domain
    8.1e-19   65.7  10.5    1.3e-06   27.5   0.2    4.4  4  EF-hand_1  EF hand
    5.2e-18   64.6   5.5    2.4e-08   33.7   0.0    4.1  5  EF-hand_8  EF-hand domain pair
    8.3e-18   64.6   2.8    3.2e-07   30.7   0.0    3.2  2  EF-hand_7  EF-hand domain pair
    2.3e-13   48.9   8.8    8.9e-06   25.0   0.5    3.9  3  EF-hand_5  EF hand
  ------ inclusion threshold ------
      0.056   13.8   0.0       0.53   10.6   0.1    2.2  2  DDT        DDT domain
       0.14   12.1   1.4         21    5.0   0.1    3.0  3  Caleosin   Caleosin related protein


Domain annotation for each model (and alignments):
>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0     0.022        57      11      26 ..     141     156 ..     131     160 .. 0.80
   2 !   18.7   0.0   4.5e-07    0.0012       5      25 ..     172     192 ..     168     196 .. 0.85
   3 !   27.6   0.1   6.2e-10   1.6e-06       2      27 ..     199     224 ..     198     227 .. 0.92
   4 !   17.3   0.2   1.2e-06    0.0032       2      19 ..     284     301 ..     283     313 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.022
   EF-hand_6  11 kdgdGkidaeElrkal 26 
                  +++G ++ +El +al
  EEA19041.1 141 ISRTGALTESELGSAL 156
                 5799*********999 PP

  == domain 2  score: 18.7 bits;  conditional E-value: 4.5e-07
   EF-hand_6   5 aFklfDkdgdGkidaeElrka 25 
                   ++fD++gdG i+++E++++
  EEA19041.1 172 MVRMFDRNGDGVIHFDEFVSL 192
                 568***************986 PP

  == domain 3  score: 27.6 bits;  conditional E-value: 6.2e-10
   EF-hand_6   2 lreaFklfDkdgdGkidaeElrkalr 27 
                 +re+F+ fD d++Gki+ eE+ kal 
  EEA19041.1 199 WRELFDRFDEDRSGKISLEEFEKALV 224
                 79*********************996 PP

  == domain 4  score: 17.3 bits;  conditional E-value: 1.2e-06
   EF-hand_6   2 lreaFklfDkdgdGkida 19 
                 + ++Fk +D d+dG+i+ 
  EEA19041.1 284 MTDVFKRYDDDRDGYITL 301
                 6699**********7775 PP

>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0      0.48   1.2e+03      13      26 ..     143     156 ..     140     158 .. 0.86
   2 !   27.0   0.1   7.3e-10   1.9e-06       2      27 ..     169     194 ..     168     196 .. 0.92
   3 !   27.5   0.2   5.1e-10   1.3e-06       2      27 ..     199     224 ..     198     226 .. 0.92
   4 !   13.2   2.2   1.8e-05     0.047       4      19 ..     286     301 ..     283     308 .. 0.90

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.48
                 SSSEEEHHHHHHHH CS
   EF-hand_1  13 gdGkIdfeEfkell 26 
                 ++G ++ +E+ ++l
  EEA19041.1 143 RTGALTESELGSAL 156
                 6799******9987 PP

  == domain 2  score: 27.0 bits;  conditional E-value: 7.3e-10
                 HHHHHHHHTTTSSSEEEHHHHHHHHH CS
   EF-hand_1   2 lkeiFrefDkDgdGkIdfeEfkellk 27 
                 +k + r+fD++gdG I f+Ef++l++
  EEA19041.1 169 VKTMVRMFDRNGDGVIHFDEFVSLWR 194
                 68899*****************9986 PP

  == domain 3  score: 27.5 bits;  conditional E-value: 5.1e-10
                 HHHHHHHHTTTSSSEEEHHHHHHHHH CS
   EF-hand_1   2 lkeiFrefDkDgdGkIdfeEfkellk 27 
                 ++e+F+ fD D++GkI++eEf ++l 
  EEA19041.1 199 WRELFDRFDEDRSGKISLEEFEKALV 224
                 79********************9986 PP

  == domain 4  score: 13.2 bits;  conditional E-value: 1.8e-05
                 HHHHHHTTTSSSEEEH CS
   EF-hand_1   4 eiFrefDkDgdGkIdf 19 
                 ++F+ +D D+dG+I++
  EEA19041.1 286 DVFKRYDDDRDGYITL 301
                 79************96 PP

>> EF-hand_8  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.0      0.25   6.4e+02      24      47 ..     128     151 ..     128     157 .. 0.88
   2 !   33.7   0.0   9.3e-12   2.4e-08       2      52 ..     144     193 ..     143     194 .. 0.87
   3 !   20.5   0.4   1.2e-07   0.00031      29      48 ..     200     219 ..     198     225 .. 0.91
   4 ?    2.7   0.0     0.044   1.1e+02       8      39 ..     217     246 ..     217     247 .. 0.90
   5 !   10.0   0.2   0.00024      0.62      28      49 ..     284     307 ..     270     310 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.25
   EF-hand_8  24 seeevdilfrefDtdgdGkisfeE 47 
                 ++++++ lf+++ + + G+++  E
  EEA19041.1 128 NPQQLRPLFYAANISRTGALTESE 151
                 6889999***********999887 PP

  == domain 2  score: 33.7 bits;  conditional E-value: 9.3e-12
   EF-hand_8   2 kgkItreelrrilrilglkk..glseeevdilfrefDtdgdGkisfeEFcvll 52 
                 +g +t  el ++l      +  ++ ++ v +++r fD++gdG+i+f+EF+ l+
  EEA19041.1 144 TGALTESELGSALVNG---DytHFDPNTVKTMVRMFDRNGDGVIHFDEFVSLW 193
                 6888999999988544...5667****************************99 PP

  == domain 3  score: 20.5 bits;  conditional E-value: 1.2e-07
   EF-hand_8  29 dilfrefDtdgdGkisfeEF 48 
                 ++lf++fD+d++Gkis+eEF
  EEA19041.1 200 RELFDRFDEDRSGKISLEEF 219
                 68****************** PP

  == domain 4  score: 2.7 bits;  conditional E-value: 0.044
   EF-hand_8   8 eelrrilrilglkkglseeevdilfrefDtdg 39 
                 ee+ ++l ++g++  ls   v++lf +f  +g
  EEA19041.1 217 EEFEKALVAFGYR--LSRTFVRVLFTTFEAKG 246
                 7999***888***..***********998776 PP

  == domain 5  score: 10.0 bits;  conditional E-value: 0.00024
   EF-hand_8  28 vdilfrefDtdgdGki..sfeEFc 49 
                 ++++f++ D d+dG+i  sfeEF+
  EEA19041.1 284 MTDVFKRYDDDRDGYItlSFEEFL 307
                 6789***********833577775 PP

>> EF-hand_7  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.7   0.0   1.2e-10   3.2e-07       2      69 ..     130     192 ..     129     194 .. 0.93
   2 !   26.8   4.4   2.1e-09   5.4e-06       5      68 ..     200     308 ..     197     310 .. 0.78

  Alignments for each domain:
  == domain 1  score: 30.7 bits;  conditional E-value: 1.2e-10
   EF-hand_7   2 eklkeaFkelDtdgdgyldkeellrllrkifqgagegsklsdeelellfkefDtdkdGvisfdEFlkl 69 
                 ++l+  F +    ++g l+++el ++l +     g   ++++  +++++++fD ++dGvi fdEF+ l
  EEA19041.1 130 QQLRPLFYAANISRTGALTESELGSALVN-----GDYTHFDPNTVKTMVRMFDRNGDGVIHFDEFVSL 192
                 5788999999999************9999.....9999***************************976 PP

  == domain 2  score: 26.8 bits;  conditional E-value: 2.1e-09
   EF-hand_7   5 keaFkelDtdgdgyldkeellrllrkifqga...................................gegsklsd........eelellfkefDtdkdG. 59 
                 +e F+ +D d++g+++ ee++++l ++                                       g+g +++         + + ++fk  D d+dG 
  EEA19041.1 200 RELFDRFDEDRSGKISLEEFEKALVAFGYRLsrtfvrvlfttfeakgrrragsitaapypggggggGRGMSFDLfvqacislKRMTDVFKRYDDDRDGy 298
                 789*******************6666555556666666666668889***************9999555555555544444477**************6 PP

   EF-hand_7  60 .visfdEFlk 68 
                  ++sf+EFl+
  EEA19041.1 299 iTLSFEEFLT 308
                 7778899975 PP

>> EF-hand_5  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   8.1e-06     0.021       6      23 ..     174     191 ..     172     195 .. 0.89
   2 !   25.0   0.5   3.5e-09   8.9e-06       3      24 ..     201     223 ..     200     224 .. 0.88
   3 !   12.0   1.0   4.5e-05      0.12       3      18 ..     286     301 ..     284     311 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 8.1e-06
                 HHH-SS-SSCE-HHHHHH CS
   EF-hand_5   6 qaiDlNgDGkIskeELkt 23 
                 +++D NgDG I ++E+  
  EEA19041.1 174 RMFDRNGDGVIHFDEFVS 191
                 68*************965 PP

  == domain 2  score: 25.0 bits;  conditional E-value: 3.5e-09
                 HHHHHH-SS-SSCE-HHHHHH.H CS
   EF-hand_5   3 dtFqaiDlNgDGkIskeELkt.l 24 
                 ++F+++D +++GkIs eE+++ l
  EEA19041.1 201 ELFDRFDEDRSGKISLEEFEKaL 223
                 68*****************8755 PP

  == domain 3  score: 12.0 bits;  conditional E-value: 4.5e-05
                 HHHHHH-SS-SSCE-H CS
   EF-hand_5   3 dtFqaiDlNgDGkIsk 18 
                 d+F++ D ++DG+I+ 
  EEA19041.1 286 DVFKRYDDDRDGYITL 301
                 79**********9964 PP

>> DDT  DDT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.1   0.00021      0.53       2      35 ..     185     224 ..     185     244 .. 0.88
   2 ?    0.8   0.0      0.24   6.2e+02      23      42 ..     267     286 ..     228     314 .. 0.60

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00021
         DDT   2 dfgdlLmvweFLhvFgelLgL......spftlddlesALl 35 
                 +f+++++ w FL   +el++         ++l+++e+AL+
  EEA19041.1 185 HFDEFVSLWRFLAAWRELFDRfdedrsGKISLEEFEKALV 224
                 6999****************99****98899********8 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.24
         DDT  23 spftlddlesALlsqdpmgp 42 
                  ++++d +++A  s   m +
  EEA19041.1 267 RGMSFDLFVQACISLKRMTD 286
                 46788888888887776665 PP

>> Caleosin  Caleosin related protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.1    0.0082        21       9      26 ..     172     189 ..     165     200 .. 0.80
   2 ?    3.8   0.0     0.019        49      13      47 ..     206     240 ..     196     254 .. 0.83
   3 ?    0.5   0.0       0.2   5.1e+02      13      23 ..     291     301 ..     279     309 .. 0.63

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0082
    Caleosin   9 HvaFfDrdkdGiiypldt 26 
                  v  fDr+ dG+i + + 
  EEA19041.1 172 MVRMFDRNGDGVIHFDEF 189
                 5889*********98765 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.019
    Caleosin  13 fDrdkdGiiypldtyrgfralgfnvllsllaalvi 47 
                 fD+d+ G i + +  ++++a+g+ +  +++ +l+ 
  EEA19041.1 206 FDEDRSGKISLEEFEKALVAFGYRLSRTFVRVLFT 240
                 99999999999999999999999888877777665 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.2
    Caleosin  13 fDrdkdGiiyp 23 
                 +D d+dG+i++
  EEA19041.1 291 YDDDRDGYITL 301
                 55666666553 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (315 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       474  (0.0264376); expected 358.6 (0.02)
Passed bias filter:                      350  (0.0195214); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.54u 0.24s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 2208.48
//
Query:       EEA19042.1  [L=607]
Description: MFS drug transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-49  167.3  67.4    8.7e-47  159.7  46.8    2.1  2  MFS_1     Major Facilitator Superfamily
    1.9e-21   76.1  16.4    1.9e-21   76.1  16.4    2.0  2  TRI12     Fungal trichothecene efflux pump (TRI12)
    1.5e-13   50.4  13.3    1.5e-13   50.4  13.3    3.3  3  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  159.7  46.8   1.5e-50   8.7e-47       1     352 [.      85     484 ..      85     485 .. 0.93
   2 !   22.0  12.6   1.1e-08   6.8e-05      42     166 ..     385     513 ..     371     572 .. 0.69

  Alignments for each domain:
  == domain 1  score: 159.7 bits;  conditional E-value: 1.5e-50
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlg 98 
                 l+l++fl+al+++i+++alp  +a +++ +   ++++++ y l+ a +++++G lsd fGr++v++l+ ++f++g+l++++ s++  + +++r++qG g
  EEA19042.1  85 LCLTVFLAALDMTIISTALP-VMAAHFHTTQGGYSWMASSYLLANASSVPFWGKLSDIFGRKPVIILANIVFLVGSLICAL-SNSLaMNIAGRAIQGGG 181
                 6899****************.******************************************************888888.88888************ PP

       MFS_1  99 agalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee......... 188
                 +g+++ ++++ ++d+++ +er++++gl++++++l+ +lgp++gg+l++ + Wr++fy++ +v+  ++ +  ++l +  p+ +   + +           
  EEA19042.1 182 GGGIIVLANITVSDLVSVRERPMYYGLFGVTWALAGALGPIIGGALTTKVTWRWCFYLNLPVGGCSLTILTFFLKVHTPKTRLLDGLKAIdwlgvvtci 280
                 ******************************************************************999899999999999999999999********* PP

       MFS_1 189 ..........................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglll 245
                                                            + ++ p++p +++++++  l  +++++++ + +f +  +++ply+q+vl  +  +l
  EEA19042.1 281 gatlmflfglefggvtypwnsatticlivfgiltygifflieWKIAKYPIIP-LRLFKNRHNLA-IFAVCFCHASVFISGAYYIPLYFQSVLLAT-PIL 376
                 *****************************************99999999999.99999999885.9999999999*****************999.333 PP

       MFS_1 246 aglllallalvgail.allagrlsdrlgr.rrrlllallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfn 342
                 +g ++ l++++++ + + ++g +++++gr +  + l++++++l++ +++ l ++ s + +++  +++G g+g  f + l++++ ++  + ++ a++ f+
  EEA19042.1 377 SG-VYTLPQVLSLSVtSAMIGIIIRKTGRyKEVISLGMGVMTLGFGLFIDLKPYASWSRIIIYQLIAGAGVGPNFQAPLVALQANIHVSDMAVATATFG 474
                 33.5888888877777889*********98889999999999999999999999666666667788999*****99999999999999*********** PP

       MFS_1 343 tagslggalg 352
                 ++++l++a+g
  EEA19042.1 475 FVRQLASAIG 484
                 ********98 PP

  == domain 2  score: 22.0 bits;  conditional E-value: 1.1e-08
       MFS_1  42 algaavaslplGrlsdrfGrrr.vlllglllfalglllllfa....sslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGa 134
                  l  +v+s  +G ++ + Gr + v+ lg+ ++ lg + l+ +      +w  +++  +++G+g g  f a ++++ +  + ++ + a++ ++   +l++
  EEA19042.1 385 VLSLSVTSAMIGIIIRKTGRYKeVISLGMGVMTLG-FGLF-IdlkpYASWsRIIIYQLIAGAGVGPNFQAPLVALQANIHVSDMAVATATFGFVRQLAS 481
                 3344888999999999*******************.5555.22345445559*********************************************** PP

       MFS_1 135 ilgpllggllasslgWravfyilaivsllafv 166
                 ++g +lg+++++++  + +  + ++v+   + 
  EEA19042.1 482 AIGIVLGSVIYQNVLAQQIPQLETVVGSATAA 513
                 ***********998888777777777777755 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.1  16.4   3.2e-25   1.9e-21      43     313 ..      79     343 ..      56     370 .. 0.81
   2 ?   -0.9   0.1     0.069   4.1e+02     512     579 ..     526     594 ..     434     604 .. 0.68

  Alignments for each domain:
  == domain 1  score: 76.1 bits;  conditional E-value: 3.2e-25
       TRI12  43 vasfaafslnvvatyfvlqasasalpnilqdvgqse.nsslfstlwttgqavsilvmgrltdrfgrrpfvilthilglvgaivgctatkfntllaamtl 140
                 +  + a+ l v  + + +   ++alp +      ++   s +++ + + +a s+   g+l+d fgr+p++il+ i+ lvg+++ + ++ +   +a  ++
  EEA19042.1  79 IIIMGALCLTVFLAALDMTIISTALPVMAAHFHTTQgGYSWMASSYLLANASSVPFWGKLSDIFGRKPVIILANIVFLVGSLICALSNSLAMNIAGRAI 177
                 4455666777777777777777888888777655441456777788999**********************************************9999 PP

       TRI12 141 lgvaagp.agasplfvgelmsnktk..flgllivsipvvvtsglspylgqrlaiqgswrwifyiyiitsaiavllivvwyyppsfaqlhgkkvrkreel 236
                  g   g     + + v +l+s + +  + gl+ v+       +l+p +g  l+ + +wrw fy+ + +   +++++        f ++h  k+r  + l
  EEA19042.1 178 QGGGGGGiIVLANITVSDLVSVRERpmYYGLFGVTWA--LAGALGPIIGGALTTKVTWRWCFYLNLPVGGCSLTILT------FFLKVHTPKTRLLDGL 268
                 987765515678999*****98776227777777654..44569*********************999988776554......37899*********** PP

       TRI12 237 akldwigiilvivgvslfllgvswggkpnspwnsakviglissglgslvvfalyevygkpvrpivppalfkdtrgfv 313
                   +dw+g++  i  + +fl+g+ +gg    pwnsa  i li  g+ +  +f l e +   + pi+p  lfk+   + 
  EEA19042.1 269 KAIDWLGVVTCIGATLMFLFGLEFGGV-TYPWNSATTICLIVFGILTYGIFFLIE-WKIAKYPIIPLRLFKNRHNLA 343
                 **************************7.57***********************99.667889*********976543 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.069
       TRI12 512 mtteiaavvsramadsytasyanvyyfamalgvipiiaslcmrdldryltdhvphq.lydrkkadkdvl 579
                 + +++ a+   a+  ++t s +  + +  alg +    s+ +r ++   +  v +  l  + ka +++l
  EEA19042.1 526 LIESLPAIQQAAIKSTFTFSLSRAWIYYTALGGVGFAISFFLRRVELNRSHAVAKTgLEAQEKARQEIL 594
                 455666677777777888887777777778888888888888887777666665532445556666665 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.4  13.3   2.6e-17   1.5e-13      10     190 ..      90     253 ..      63     260 .. 0.85
   2 ?   -1.5   6.4      0.15   8.8e+02     321     367 ..     279     323 ..     276     355 .. 0.82
   3 ?    1.8   8.5     0.015        87      57     160 ..     386     494 ..     367     500 .. 0.72

  Alignments for each domain:
  == domain 1  score: 50.4 bits;  conditional E-value: 2.6e-17
                 HHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGG CS
    Sugar_tr  10 llfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivg 108
                 +l   d+ +i+++l +++     ++ ++++        +++++s++l+  + +  f g+l+d+fGRk++++ a+++f++g++++a+++   s+ + i+g
  EEA19042.1  90 FLAALDMTIISTALPVMA----AHFHTTQG-------GYSWMASSYLLANASSVPFWGKLSDIFGRKPVIILANIVFLVGSLICALSN---SLAMNIAG 174
                 555555555555555555....22222222.......2469***********************************************...******** PP

                 HHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGG CS
    Sugar_tr 109 RvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllf 190
                 R + G g G++ vl+ +++s +   + R +  +l+ + +++   ++ i+g +l +      wr+ ++l+l      l +l+f
  EEA19042.1 175 RAIQGGGGGGIIVLANITVSDLVSVRERPMYYGLFGVTWALAGALGPIIGGALTTKVT---WRWCFYLNLPVGGCSLTILTF 253
                 **************************************************99988777...999999999887665555544 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.15
                 HHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHH.HHHHHHHHHTTT CS
    Sugar_tr 321 llGaagmaicfvilgivalllvakskaasivaivf.ialfialfalgw 367
                  +Ga+ m+++ + +g+v++++++++   +i++ivf i+ + ++f + w
  EEA19042.1 279 CIGATLMFLFGLEFGGVTYPWNSAT---TICLIVFgILTYGIFFLIEW 323
                 589999999999999********97...88888762566888887766 PP

  == domain 3  score: 1.8 bits;  conditional E-value: 0.015
                 HHHHHHHHHHHHHHHHTTHHHHHHH.HHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHH......HHHHHHHHHHHTTS-SCCHHHHHHHHHHHHH CS
    Sugar_tr  57 vGaiiGslfagllgdrfGRkkslli.aavlfvigavlqaaakgknsvevlivgRvlvGigvG......lasvlvPmyisEiApkklRgalvslyqlait 148
                 +   ++s ++g+++ + GR k  +  +  ++  g  l +  k + s+  +i+ ++++G gvG      l+   + + +s +A ++   +++ + qla +
  EEA19042.1 386 LSLSVTSAMIGIIIRKTGRYKEVISlGMGVMTLGFGLFIDLKPYASWSRIIIYQLIAGAGVGpnfqapLVALQANIHVSDMAVAT--ATFGFVRQLASA 482
                 5567899************88877733344444555555555579*****************55222223333444555555544..689999****** PP

                 HHHHHHHHHHHH CS
    Sugar_tr 149 fGilvaaifglg 160
                 +Gi+++++++ +
  EEA19042.1 483 IGIVLGSVIYQN 494
                 *******99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (607 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       846  (0.0471861); expected 358.6 (0.02)
Passed bias filter:                      405  (0.0225891); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.66u 0.31s 00:00:00.97 Elapsed: 00:00:00.57
# Mc/sec: 3184.12
//
Query:       EEA19043.1  [L=232]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (232 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       267  (0.0148921); expected 358.6 (0.02)
Passed bias filter:                      253  (0.0141112); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.27s 00:00:00.67 Elapsed: 00:00:00.40
# Mc/sec: 1721.00
//
Query:       EEA19044.1  [L=533]
Description: O-methylsterigmatocystin oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.6e-68  230.4   0.0    4.1e-68  230.2   0.0    1.0  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  230.2   0.0   2.3e-72   4.1e-68       1     448 [.      52     484 ..      52     502 .. 0.88

  Alignments for each domain:
  == domain 1  score: 230.2 bits;  conditional E-value: 2.3e-72
                 --SESEHHCCHCHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGH.HHHHHH CS
        p450   1 Ppgptplplvgnllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfang.ekwkkl 98 
                 Ppgp++lp++gnl+q++    +++ + +  k+ygpifrlk g+ ++++l++ +a++ +l kk++  s+rp++++    ++ +kg   +++   e+wk  
  EEA19044.1  52 PPGPPALPIIGNLHQMSL-SAPWKQHLEWTKQYGPIFRLKAGKDTMIILGTMQAARDLLDKKSKIYSSRPRSVMAF--ENVSKGLRPVLMPDnEQWKTA 147
                 99***************8.57777799999**************************************96655544..478888777777666****** PP

                 HHHHHHHHTSHSTTTHHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCCCHH CS
        p450  99 RrfltptltsfgklsleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelssllskssvqllllfpl 197
                 +r+    lt++ ++s++ +   e+ +l++ l ++ g+      ++ + ++ +++++ +++g r+   +de++ ++++++ e + l+    + +++++p+
  EEA19044.1 148 KRLQGVVLTYKMSQSYRGVQALESLQLLRGLLQNEGKF-----QKEFHRYSTSTLFALAYGQRMT-RGDEDEVKAIDLIMERFALFGRVGTWIVDVIPV 240
                 *********99666999999999999999999988887.....8*******************99.9999999*************999999******* PP

                 HTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHH CS
        p450 198 lkylptkllrklkeavkklkdlldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevq 296
                 l ylpt +l  +k++ ++ +++   +  ++ ++  ++     +f++a+ + k      + +s++ela  v  ll aG +Tt+++l+ + +     P + 
  EEA19044.1 241 LNYLPT-FLAPWKRIAEECHQFESTMHMKHLHQAMER--PGWNFVKAVKDVK---AA-EGVSQKELAYIVAILLEAGAETTTNALETFVLAARLFPRII 332
                 **9995.566677787877777777777777776666..6788888887776...22.469************************************** PP

                 HHHHHHHHHHCCTTTT-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEETTEEE-TT-EEEEEHHHHHT-TTTSSSTTS--GGGGB-TTSCT CS
        p450 297 eklreEidevlgdkreptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirgylipkGtevivnlyalhrdpevfpnPeeFdpeRFldekgns 395
                    + E+++v+g +r pt dd  +lpy +a++kEtLR +p+vp  +p+  t++ +  gy ipkG+++++n++++h +p+++p+P++F peR+l  +   
  EEA19044.1 333 GPAQAELESVIGTSRLPTVDDSPNLPYINAIVKETLRWRPIVPEAVPHLNTEEDEYMGYRIPKGSIILPNVWGIHLNPDIYPDPNNFLPERWLAYET-- 429
                 ***********************************************************************************************98.. PP

                 ESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEE..EESTSTSGGEEES CS
        p450 396 krksfaflPFGaGpRnCiGerlArmelklflatlLqnFev..elqpetdpppile 448
                 +  + ++ +FG+G+R+C G+++A+  l+l +a++L  +++  +++ e+++ p +e
  EEA19044.1 430 NEGPPEHAAFGFGRRICTGQHIAYNSLFLNIARILWACNIgpKIDAEGREVPVDE 484
                 47999******************************88876223344445555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (533 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       556  (0.0310112); expected 358.6 (0.02)
Passed bias filter:                      523  (0.0291706); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 3746.44
//
Query:       EEA19045.1  [L=706]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.4e-18   66.1   0.9    2.4e-18   66.1   0.9    1.8  2  Fungal_trans  Fungal specific transcription factor domain
    5.2e-09   36.1   9.2    8.8e-09   35.4   9.2    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
       0.12   12.7   1.2        0.3   11.5   1.2    1.6  1  MAGP          Microfibril-associated glycoprotein (MAGP)


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.1   0.9   4.1e-22   2.4e-18       3     193 ..     255     443 ..     254     514 .. 0.90
   2 ?   -1.8   0.1      0.21   1.2e+03     230     238 ..     589     661 ..     537     685 .. 0.48

  Alignments for each domain:
  == domain 1  score: 66.1 bits;  conditional E-value: 4.1e-22
  Fungal_trans   3 rffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLll 99 
                   +ff ++h  +p+++++ f+++    + s  +     l ++i  lG++ ++++   + +  ++ + +        +i  ++d  + ++sl++lq+  l
    EEA19045.1 255 SFFNYVHAVLPMVNRHRFFNEL---EVSGHRPEMKSLSYSIALLGSTVTPEQVEAERNFYHHAR-K------YLSIAESDDEAPGFNSLNMLQAVIL 341
                   8*********************...6666666777788**************999988888765.2......44566699999************** PP

  Fungal_trans 100 lelyektssdralherhhgvavrlarslgLhrnpsyvgkks.........lwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPc 187
                   +++ye+ +++ a +++ +g a rla+ lgLh    ++++k+          +   ++  e+rrR +w  F +D + ++ +G  + +dd++i+++LPc
    EEA19045.1 342 IAYYEFRRTSFARAWLSLGRANRLAKMLGLHAMDQDSKTKRrsnfvlplpEPAGLAD-MEERRRSFWVLFTFDAYASIRTGSKTSIDDEEISTSLPC 437
                   ********************************999999888**9*999765555555.889***********************99*********** PP

  Fungal_trans 188 ddddlw 193
                     d+ +
    EEA19045.1 438 PGDFSD 443
                   999654 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.21
  Fungal_trans 230 k................................................................iagsllsi 238
                   +                                                                ++++l +i
    EEA19045.1 589 QlqnskvsyspskasgpmnltvnfaclihikwisntfmmwpfsvasqallrqlnepttnvrevatLLHQLWCI 661
                   4444444444444444444444333333333333333333333333333333333333333333322223333 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.4   9.2   1.5e-12   8.8e-09       2      36 ..      64      97 ..      63     101 .. 0.91

  Alignments for each domain:
  == domain 1  score: 35.4 bits;  conditional E-value: 1.5e-12
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfyses 36
                aCd Cr +Kv+Cd+ +P+C++C+kl+ +C  y+  
  EEA19045.1 64 ACDICRGRKVRCDRVHPVCGRCRKLGHKCG-YTAH 97
                9****************************9.7654 PP

>> MAGP  Microfibril-associated glycoprotein (MAGP)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   1.2     5e-05       0.3      39     130 ..      32     118 ..       6     122 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 5e-05
        MAGP  39 tviedpnlvndpatdeteptvladiePstdDlasdknasaeCreekypCtrlysvhkPvkqClkqlcfyslrrvYiinkeiCvrlvCkeeel 130
                  ++e p+  +d  t+e + +      Ps  D++s + a+  Cr  k  C r+  v   +++  ++  +++ r+   +  +i   l+  +e l
  EEA19045.1  32 ALMERPTEKEDMGTEENRVS-----RPSSRDQSSRRIACDICRGRKVRCDRVHPVCGRCRKLGHKCGYTAHRKPDTVKPNISQALISLHERL 118
                 34444444444444443333.....8***********************************9999999999998888888887777777655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (706 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       511  (0.0285013); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.66u 0.33s 00:00:00.99 Elapsed: 00:00:00.52
# Mc/sec: 4110.19
//
Query:       EEA19046.1  [L=140]
Description: hypothetical protein PMAA_013130 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
     0.0049   16.4   0.0     0.0061   16.1   0.0    1.0  1  Acyl_transf_1  Acyl transferase domain


Domain annotation for each model (and alignments):
>> Acyl_transf_1  Acyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0   3.4e-07    0.0061     237     300 ..      17      82 ..      13      98 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 3.4e-07
                    HHHHHHCHCCHCCHHTTS...SSECC-CCEECSSSSCCHCCCCCCCHHGGG-TCCCCCCTEETTSS- CS
  Acyl_transf_1 237 wvanlrspvrfaeavlsa...aetiplvfveispHslllaalektlksaedvksatlvGklkrdltd 300
                    w +nl spv+f++av+ +    +   ++ +ei pH +l   +++  ++  + ++   +++l r+ + 
     EEA19046.1  17 WCQNLISPVLFNQAVQTLatsDDLSVDALIEIKPHTTLSGPIKQICRE-FGYNNLGYIPTLVRNEDS 82 
                    889*************9965445677899************9999995.788888888888888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (140 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       248  (0.0138323); expected 358.6 (0.02)
Passed bias filter:                      243  (0.0135535); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.33s 00:00:00.89 Elapsed: 00:00:00.55
# Mc/sec: 766.19
//
Query:       EEA19047.1  [L=583]
Description: SRF-type transcription factor RlmA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.5e-24   84.0   0.2    5.6e-24   83.4   0.2    1.3  1  SRF-TF    SRF-type transcription factor (DNA-binding and dime


Domain annotation for each model (and alignments):
>> SRF-TF  SRF-type transcription factor (DNA-binding and dimerisation domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.4   0.2   3.1e-28   5.6e-24       2      48 .]      11      57 ..      10      57 .. 0.99

  Alignments for each domain:
  == domain 1  score: 83.4 bits;  conditional E-value: 3.1e-28
      SRF-TF  2 IeneraRqvtFsKRrnGLfKKAsELsvLcgvevavvvfspngklytf 48
                I+++r+R+vtF KR+ GLfKKA+ELsvLc+v+vav++f++n+kly+f
  EEA19047.1 11 IKDDRNRSVTFLKRKGGLFKKAHELSVLCSVDVAVIIFGHNKKLYEF 57
                99********************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (583 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       602  (0.0335769); expected 358.6 (0.02)
Passed bias filter:                      237  (0.0132188); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.80u 0.38s 00:00:01.18 Elapsed: 00:00:00.57
# Mc/sec: 3068.72
//
Query:       EEA19048.1  [L=1027]
Description: morphogenesis protein (Msb1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.1e-178  594.9   0.0   2.1e-178  593.9   0.0    1.5  2  DUF1708   Domain of unknown function (DUF1708)


Domain annotation for each model (and alignments):
>> DUF1708  Domain of unknown function (DUF1708)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  593.9   0.0  1.2e-182  2.1e-178       1     431 []      42     515 ..      42     515 .. 0.98
   2 ?   -3.4   0.1      0.22   3.9e+03     247     316 ..     621     693 ..     609     751 .. 0.63

  Alignments for each domain:
  == domain 1  score: 593.9 bits;  conditional E-value: 1.2e-182
     DUF1708   1 evereevkelihliteelKargldtpfllLpFrpesdpsalrtflrnfFpkgqeegsslkgeellqelrktdiltLisvlkylWsrlpggvvgwdaYee 99 
                 ev++eev+el++ +t+elK+rgl +pfllLpFrp+sdpsa+rtf+rnfF+ +q +g++l+g++l+qelr+t++++L+sv+k++Wsrlpggvv+wdaYe 
  EEA19048.1  42 EVAPEEVQELLRGCTHELKSRGLGIPFLLLPFRPSSDPSAVRTFIRNFFNAEQ-KGTPLQGDALMQELRLTEPMVLCSVVKWCWSRLPGGVVTWDAYEL 139
                 5899**********************************************755.6******************************************** PP

     DUF1708 100 FkkkEkeselprdaFltfipkslssearasivydFldLlvaiaahgkknglggrklsrlaglwAFehkdkgnsfeeglkswskaadAlshLflayLrsl 198
                 Fk++E++s+l+rdaF+tfip+s++s+ar++i++dF+dLl+aiaahgk+nglggrklsr+ag+wAFeh+d+gn+fe+++k+w+ aadA+shLf+ayLrs+
  EEA19048.1 140 FKVGEQDSDLARDAFNTFIPISVDSDARTKIIFDFFDLLTAIAAHGKSNGLGGRKLSRYAGWWAFEHTDTGNGFEASYKTWALAADATSHLFFAYLRSI 238
                 *************************************************************************************************** PP

     DUF1708 199 lpekeketeg.sklprsLqkllqeteYPPekstllqsstlltvplvvlivdkvsptpfaLLrrakktlkfdnkdaFeareddalLkelfkeledivkal 296
                 +p++ + ++g s lp+ Lq+l+q teYPP++++llq st    ++vv+ivd+vsptpfaLLrra++         Fe+r++d++L+ ++ ++ed+vkal
  EEA19048.1 239 SPDSIRGINGiSALPIALQSLVQATEYPPQAPSLLQFST----TKVVMIVDTVSPTPFALLRRARN---------FEYRDSDKHLQDFS-DYEDPVKAL 323
                 **********999**************************....***********************.........**************.********* PP

     DUF1708 297 seeskrvlkaissanqsq.ss...stsledaswsrfkdigfeaglee.ee.........................rpttpsWadflssgl......... 356
                 ++e+ rvlkais++nqs+ s+   stsl+daswsrf+d+gf a++++ ++                         rpttpsWadflssg+         
  EEA19048.1 324 TDECARVLKAISTTNQSAvSTtktSTSLRDASWSRFEDMGFGASIDSdHDddiieerptvqelrsapqsrtndlgRPTTPSWADFLSSGFaddnasrgp 422
                 *****************9855678********************944233589********************************************** PP

     DUF1708 357 ...................kssqsdkkelelkeelepgelasvsrvdiddyFiwvWlsslsseetsekkalfGrslvieteikgfkkWlvveeq 431
                                    +ssqs+k++l+++ +lepgelas++ +didd+F+wvW+ssls ee++ +ka+fGr++++et i+g  kWlv+eeq
  EEA19048.1 423 sslllppdkvlppigsvrgQSSQSHKRTLDTEPNLEPGELASITVLDIDDSFWWVWISSLSGEEPAARKAVFGRCALLETVISG-AKWLVLEEQ 515
                 ************************************************************************************.*******97 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 0.22
     DUF1708 247 vdkvsptpfaLLrrakktlkfdnkdaFearedd...alLkelfkeledivkalseeskrvlkaissanqsq.ss 316
                 +++v  + + LL  a++ +k+ ++ + +++ d+   a L      +  +  +l ++  r + ++s +n+s  ++
  EEA19048.1 621 TNSVMTQYTGLLTEASSAMKWAKHYDNHYDKDQlrsAYLSDTRAGTGAPAASLLSSNGRAMSNVS-ENRSDvQK 693
                 56677777778888888777777766555554311123333333667777777777788888888.44444222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1027 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1340  (0.0747392); expected 358.6 (0.02)
Passed bias filter:                      551  (0.0307323); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 1.03u 0.38s 00:00:01.41 Elapsed: 00:00:00.58
# Mc/sec: 5340.99
//
Query:       EEA19049.1  [L=360]
Description: hypothetical protein PMAA_013160 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.2e-27   93.9   0.1    7.2e-27   93.9   0.1    2.4  2  DUF2406          Uncharacterised protein (DUF2406)
  ------ inclusion threshold ------
      0.039   14.5   0.4      0.039   14.5   0.4    2.9  2  Caskin-Pro-rich  Proline rich region of Caskin proteins


Domain annotation for each model (and alignments):
>> DUF2406  Uncharacterised protein (DUF2406)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.9   0.1   8.1e-31   7.2e-27       1      64 []      76     138 ..      76     138 .. 0.97
   2 ?   -1.4   0.8      0.45     4e+03      10      22 ..     268     280 ..     221     302 .. 0.68

  Alignments for each domain:
  == domain 1  score: 93.9 bits;  conditional E-value: 8.1e-31
     DUF2406   1 AvseaqPfeqaad.klslaalrsiqrsykDvfGkeiadpDlSNPtRsRdERPLdTIRsFeaaieG 64 
                 A++eaqP+++a+  k++l +lrsiq+  kD++G+ i+dpDlSNPtR+R+ERPLdTIRsFeaai+G
  EEA19049.1  76 AMNEAQPAMVATLeKSNLGSLRSIQH--KDQYGNVITDPDLSNPTRPRFERPLDTIRSFEAAIDG 138
                 8*********999677**********..***********************************98 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.45
     DUF2406  10 qaadklslaalrs 22 
                 qa+++++++++++
  EEA19049.1 268 QAVQQKQYQQQQQ 280
                 2333233333333 PP

>> Caskin-Pro-rich  Proline rich region of Caskin proteins
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   3.2      0.85   7.6e+03      69      86 ..      10      27 ..       5      31 .. 0.66
   2 ?   14.5   0.4   4.4e-06     0.039      28      81 ..     256     316 ..     233     324 .. 0.67

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.85
  Caskin-Pro-rich 69 kkGPPPPPPkRlssvsss 86
                     +  PP P P  +ss++s 
       EEA19049.1 10 QNQPPLPSPPISSSTTSP 27
                     556777777777777765 PP

  == domain 2  score: 14.5 bits;  conditional E-value: 4.4e-06
  Caskin-Pro-rich  28 saelgsYatltrrpgRsqlvraqaaaek.nvnR......sqsfavRarkkGPPPPPPkRls 81 
                      s+  +s+  l++++   +  ++q++ae  + n       + sf     + GPPPPPP   s
       EEA19049.1 256 SSVNSSFDRLQQQAVQQKQYQQQQQAESyGYNGsggnpdATSFHPQDNHNGPPPPPPHGQS 316
                      555566666766666666666666665543332222334789***************9776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (360 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       871  (0.0485805); expected 358.6 (0.02)
Passed bias filter:                      314  (0.0175135); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.66u 0.39s 00:00:01.05 Elapsed: 00:00:00.59
# Mc/sec: 1840.82
//
Query:       EEA19050.1  [L=155]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.3e-22   78.9  11.3    3.6e-21   75.5   5.3    2.6  3  DUF3602   Protein of unknown function (DUF3602)


Domain annotation for each model (and alignments):
>> DUF3602  Protein of unknown function (DUF3602)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.3   4.7e-06     0.083      28      46 ..      13      31 ..       1      33 [. 0.64
   2 !   75.5   5.3     2e-25   3.6e-21       1      81 []      26     104 ..      26     104 .. 0.97
   3 ?   -2.0   0.1      0.31   5.6e+03       8       8 ..     121     121 ..     108     141 .. 0.49

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 4.7e-06
     DUF3602 28 ttsafstGRGGaGNihssd 46
                +   +s GRGG GNi+ ++
  EEA19050.1 13 EAPIVSHGRGGQGNIGADP 31
                2237999********9665 PP

  == domain 2  score: 75.5 bits;  conditional E-value: 2e-25
     DUF3602   1 NiikdktkytdgeivrtgpqgsktdgsttsafstGRGGaGNihssdrerpe...trkdedvereearrkeeaeeyhvGRGGaGN 81 
                 Ni++d t+y+dgeivr gp+g+++dg    a+s+GRGGaGNi+ s++ rp+     +d+ v++e+a+r++ + +yh+GRGG+GN
  EEA19050.1  26 NIGADPTVYVDGEIVRSGPTGDQGDG----AYSAGRGGAGNIG-SPHVRPStpgVVHDNVVVPETAVRESLDGDYHTGRGGQGN 104
                 9*************************....*************.888**9989899*************999***********9 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 0.31
     DUF3602   8 k 8  
                 +
  EEA19050.1 121 T 121
                 1 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (155 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       369  (0.0205812); expected 358.6 (0.02)
Passed bias filter:                      272  (0.015171); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.44
# Mc/sec: 1061.54
//
Query:       EEA19051.1  [L=368]
Description: mitochondrial phosphate carrier protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.9e-46  156.0   6.7    9.4e-18   63.9   0.1    3.1  3  Mito_carr  Mitochondrial carrier protein


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.9   0.1   5.2e-22   9.4e-18       5      94 ..      74     158 ..      70     160 .. 0.94
   2 !   55.4   0.1   2.4e-19   4.4e-15       7      95 ..     173     257 ..     168     259 .. 0.94
   3 !   39.2   0.4   2.7e-14   4.8e-10       5      92 ..     272     354 ..     268     357 .. 0.93

  Alignments for each domain:
  == domain 1  score: 63.9 bits;  conditional E-value: 5.2e-22
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
   Mito_carr   5 vlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlll 94 
                 +++  + G+la+ ++++++tPld+vK+r q++++ +k       +++ k iy+ eG+rg + G++p++++++ + a k + ye++k ++ 
  EEA19051.1  74 YAACSFGGLLACGLTHTAVTPLDLVKCRRQVDPTLYKG-----NMEAWKLIYRAEGVRGVFTGWSPTFFGYSAQGAFKYGGYEFFKSFYS 158
                 5667788****************************999.....79*****************************************9985 PP

  == domain 2  score: 55.4 bits;  conditional E-value: 2.4e-19
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCT CS
   Mito_carr   7 kellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlllk 95 
                  +l+a++ a  +a ++ +P++ vK+r qt     ++     ++d + ki+ +eG +gl++Gl p + r++p++++kf+++et+ ++++ 
  EEA19051.1 173 VYLAASASAEFFADIALCPFEAVKVRTQTTMPPFATG----TFDGINKIVAKEGSAGLFKGLYPLWGRQIPYTMMKFASFETIVEMIYG 257
                 57899****************************9874....9******************************************99875 PP

  == domain 3  score: 39.2 bits;  conditional E-value: 2.7e-14
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   5 vlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrl 92 
                 ++  +  G lag++ ++v +P dv+  +l + +  +++     +  ++++iyk+ G+ gl+ Gl+++++++   ++l++++y+++k +
  EEA19051.1 272 TAVAFTGGYLAGILCAIVSHPADVMVSKLNALRLPGEA-----FGVAMSRIYKDIGFGGLWNGLGVRIVMIGTLTGLQWMIYDSFKIF 354
                 6677999****************************998.....8899**************************************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (368 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       394  (0.0219756); expected 358.6 (0.02)
Passed bias filter:                      341  (0.0190195); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.66u 0.37s 00:00:01.03 Elapsed: 00:00:00.59
# Mc/sec: 1879.62
//
Query:       EEA19052.1  [L=286]
Description: mitochondrial phosphate carrier protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    9.8e-45  150.4   5.8    2.4e-15   56.2   0.0    3.1  3  Mito_carr  Mitochondrial carrier protein


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.2   0.0   1.3e-19   2.4e-15      18      94 ..       5      76 ..       3      78 .. 0.95
   2 !   56.0   0.1   1.5e-19   2.7e-15       7      95 ..      91     175 ..      86     177 .. 0.94
   3 !   39.9   0.4   1.7e-14     3e-10       4      92 ..     189     272 ..     186     275 .. 0.93

  Alignments for each domain:
  == domain 1  score: 56.2 bits;  conditional E-value: 1.3e-19
                HHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
   Mito_carr 18 vatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlll 94
                ++++++tPld+vK+r q++++ +k       +++ k iy+ eG+rg + G++p++++++ + a k + ye++k ++ 
  EEA19052.1  5 LTHTAVTPLDLVKCRRQVDPTLYKG-----NMEAWKLIYRAEGVRGVFTGWSPTFFGYSAQGAFKYGGYEFFKSFYS 76
                6799******************999.....79*****************************************9985 PP

  == domain 2  score: 56.0 bits;  conditional E-value: 1.5e-19
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCT CS
   Mito_carr   7 kellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlllk 95 
                  +l+a++ a  +a ++ +P++ vK+r qt     ++     ++d + ki+ +eG +gl++Gl p + r++p++++kf+++et+ ++++ 
  EEA19052.1  91 VYLAASASAEFFADIALCPFEAVKVRTQTTMPPFATG----TFDGINKIVAKEGSAGLFKGLYPLWGRQIPYTMMKFASFETIVEMIYG 175
                 57899****************************9874....9******************************************99875 PP

  == domain 3  score: 39.9 bits;  conditional E-value: 1.7e-14
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   4 svlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrl 92 
                 +++  +  G lag++ ++v +P dv+  +l + +  +++     +  ++++iyk+ G+ gl+ Gl+++++++   ++l++++y+++k +
  EEA19052.1 189 QTAVAFTGGYLAGILCAIVSHPADVMVSKLNALRLPGEA-----FGVAMSRIYKDIGFGGLWNGLGVRIVMIGTLTGLQWMIYDSFKIF 272
                 56678999****************************998.....8899**************************************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (286 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       271  (0.0151152); expected 358.6 (0.02)
Passed bias filter:                      220  (0.0122706); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.32s 00:00:00.95 Elapsed: 00:00:00.55
# Mc/sec: 1560.64
//
Query:       EEA19053.1  [L=188]
Description: cystathionine beta-synthase (beta-thionase), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.9e-08   32.6   0.2       0.17   12.3   0.0    3.7  3  CBS       CBS domain


Domain annotation for each model (and alignments):
>> CBS  CBS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.3   0.0   9.6e-06      0.17       1      48 [.      40      88 ..      40      97 .. 0.79
   2 !    6.4   0.0   0.00071        13      12      30 ..     100     118 ..      98     127 .. 0.79
   3 !   10.5   0.1   3.5e-05      0.63      11      55 ..     123     184 ..     117     186 .. 0.61

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 9.6e-06
                HHHHSBSSCEEEETTSBHHHHHHH.HHHHTSSEEEEEETTTB.EEEEEEH CS
         CBS  1 Vgdimtrdvvtvppdttleealel.mrekgvsrlPVVdedgk.lvGivtl 48
                V+d+  ++ ++v+p+++++ al   + e+++s+l V+ ++ + l+G+++ 
  EEA19053.1 40 VEDLDPPPALSVSPNDSISSALLAaY-ERDYSHLTVISSSTRaLLGYLSI 88
                5677445667************7745.777****99977776599**996 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.00071
                 EETTSBHHHHHHHHHHHTS CS
         CBS  12 vppdttleealelmrekgv 30 
                 v+++++++ a++++ +k+ 
  EEA19053.1 100 VSESDPVKAAMQRFNRKRT 118
                 89************88774 PP

  == domain 3  score: 10.5 bits;  conditional E-value: 3.5e-05
                 EEETTSBHHHHHHHHHH.................HT.SSEEEEEETTTB.EEEEEEHHHHHHHH CS
         CBS  11 tvppdttleealelmre.................kg.vsrlPVVdedgk.lvGivtlrDllral 55 
                 +++ dt+lee+ + ++                  k  + ++ V+d   k ++G+vt+ Dl +++
  EEA19053.1 123 VITMDTPLEELERFFKGepmtpregkvnstagmgKQdF-AI-VTDPTRKfVLGVVTEGDLQEFV 184
                 67778888888888831344444444444433321124.66.7776667566*******98775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (188 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       346  (0.0192983); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.35s 00:00:00.92 Elapsed: 00:00:00.55
# Mc/sec: 1030.29
//
Query:       EEA19054.1  [L=123]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.5e-13   49.1   5.5    6.6e-13   48.6   5.5    1.3  1  VMA21     VMA21-like domain
  ------ inclusion threshold ------
      0.015   14.9   0.0      0.019   14.6   0.0    1.2  1  TMEM100   Transmembrane protein 100


Domain annotation for each model (and alignments):
>> VMA21  VMA21-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.6   5.5   7.4e-17   6.6e-13       2      64 .]      53     107 ..      52     107 .. 0.97

  Alignments for each domain:
  == domain 1  score: 48.6 bits;  conditional E-value: 7.4e-17
       VMA21   2 vikkLllfsllmvtlPlasfftskhllfegvfglsnssatlysgvlAVivvnlvlasYiivAf 64 
                 +i+kLl f+++m+  Pl+++f+s +++f+g        +++ +g lA++++n+vl++Y+ivA+
  EEA19054.1  53 TIYKLLAFTFAMICGPLGAYFLSIKTFFSG--------NSTLAGGLAALTANVVLIAYVIVAW 107
                 79***************************7........79**********************9 PP

>> TMEM100  Transmembrane protein 100
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.0   2.1e-06     0.019      77     123 ..      78     122 ..      57     123 .] 0.86

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 2.1e-06
     TMEM100  77 tfnshgsvisvlglvLLsaGlvllassavCWkvrrrrkkerrreset 123
                 tf s +s+    gl+ L+a +vl+a   v W+  ++  +++r+e+++
  EEA19054.1  78 TFFSGNST-LAGGLAALTANVVLIAYVIVAWQEDKED-QAKRKEKKG 122
                 56677777.5679*******************99888.999999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (123 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       649  (0.0361983); expected 358.6 (0.02)
Passed bias filter:                      414  (0.0230911); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.34s 00:00:00.90 Elapsed: 00:00:00.54
# Mc/sec: 689.93
//
Query:       EEA19055.1  [L=109]
Description: 60S ribosomal protein L35Ae [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.3e-44  149.0   0.4    3.7e-44  148.8   0.4    1.0  1  Ribosomal_L35Ae  Ribosomal protein L35Ae
     0.0002   21.5   0.0       0.17   12.1   0.0    2.2  2  RimM             RimM N-terminal domain
  ------ inclusion threshold ------
       0.23   11.2   1.2        1.8    8.4   0.2    2.2  2  DUF2080          Putative transposon-encoded protein (DUF2080


Domain annotation for each model (and alignments):
>> Ribosomal_L35Ae  Ribosomal protein L35Ae
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  148.8   0.4   6.2e-48   3.7e-44       1      95 []       9     103 ..       9     103 .. 1.00

  Alignments for each domain:
  == domain 1  score: 148.8 bits;  conditional E-value: 6.2e-48
                      -EEEEEEEEEE--SSSSS-EEEEEEESS--SHHHHHCCTT-EE..EEE-......TTT-EEEEEEEEECTTTTEEEEEETT--SSS-TT-EEEE CS
  Ribosomal_L35Ae   1 LyvkavflgykrgkrnqrentaLlkiegvkskeeaefylGkrvayvykakkkkkgskvrviwGkvtrahGnsgvvrakFkknLppkaigarvrv 94 
                      Lyvk+++l+y+rgkrn+++nt+L+kiegv++ + a+fylGk+va+vy+ kk+++gsk+rviwGkvtr+hGnsgvvra+F++nLpp+++ga+vrv
       EEA19055.1   9 LYVKGRHLSYQRGKRNTNPNTSLIKIEGVDDVSAANFYLGKKVAFVYRGKKEVQGSKIRVIWGKVTRPHGNSGVVRAQFRHNLPPQTFGATVRV 102
                      8********************************************************************************************* PP

                      . CS
  Ribosomal_L35Ae  95 m 95 
                      m
       EEA19055.1 103 M 103
                      9 PP

>> RimM  RimM N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.1   0.0   2.9e-05      0.17      45      78 ..      16      51 ..       4      57 .. 0.76
   2 !    7.7   0.0   0.00067         4       2      20 ..      70      88 ..      69     108 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 2.9e-05
                E-EEEEEEE..TTEEEEEETT--SHHHHHTTTT-EE CS
        RimM 45 ltvesvrvh..kkgvivklegvddrdaAealkgael 78
                l+ ++++ +   ++ ++k+egvdd++aA  + g ++
  EEA19055.1 16 LSYQRGKRNtnPNTSLIKIEGVDDVSAANFYLGKKV 51
                6666677555699***************98888877 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.00067
                EEEEEEEETTTTEEEEEE- CS
        RimM  2 vGkIvgahGlkGevkVkpf 20
                 Gk++++hG  G v+ +  
  EEA19055.1 70 WGKVTRPHGNSGVVRAQFR 88
                59************98765 PP

>> DUF2080  Putative transposon-encoded protein (DUF2080)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.1     0.032   1.9e+02      37      43 ..      46      52 ..      39      55 .. 0.81
   2 ?    8.4   0.2    0.0003       1.8       6      31 ..      58      83 ..      55     103 .. 0.77

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.032
     DUF2080 37 ylGkkvy 43
                ylGkkv 
  EEA19055.1 46 YLGKKVA 52
                9****96 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0003
     DUF2080  6 ktwlkvkeilpffegkVkpfGnSAkv 31
                k++++  +i + + ++  p+GnS+ v
  EEA19055.1 58 KKEVQGSKIRVIWGKVTRPHGNSGVV 83
                667777777777777778******88 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (109 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       230  (0.0128284); expected 358.6 (0.02)
Passed bias filter:                      202  (0.0112667); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.32s 00:00:00.86 Elapsed: 00:00:00.53
# Mc/sec: 619.63
//
Query:       EEA19056.1  [L=88]
Description: 60S ribosomal protein L35Ae [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.6e-30  103.4   0.3    6.4e-30  103.2   0.3    1.0  1  Ribosomal_L35Ae  Ribosomal protein L35Ae
  ------ inclusion threshold ------
      0.012   15.8   0.1        0.1   12.8   0.0    2.0  2  RimM             RimM N-terminal domain


Domain annotation for each model (and alignments):
>> Ribosomal_L35Ae  Ribosomal protein L35Ae
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.2   0.3   7.1e-34   6.4e-30       1      75 [.       9      83 ..       9      86 .. 0.97

  Alignments for each domain:
  == domain 1  score: 103.2 bits;  conditional E-value: 7.1e-34
                     -EEEEEEEEEE--SSSSS-EEEEEEESS--SHHHHHCCTT-EE..EEE-......TTT-EEEEEEEEECTTTTEE CS
  Ribosomal_L35Ae  1 LyvkavflgykrgkrnqrentaLlkiegvkskeeaefylGkrvayvykakkkkkgskvrviwGkvtrahGnsgvv 75
                     Lyvk+++l+y+rgkrn+++nt+L+kiegv++ + a+fylGk+va+vy+ kk+++gsk+rviwGkvtr+hG++ ++
       EEA19056.1  9 LYVKGRHLSYQRGKRNTNPNTSLIKIEGVDDVSAANFYLGKKVAFVYRGKKEVQGSKIRVIWGKVTRPHGTTTTI 83
                     8*********************************************************************98765 PP

>> RimM  RimM N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   1.2e-05       0.1      45      78 ..      16      51 ..       4      57 .. 0.76
   2 ?    0.8   0.0     0.063   5.7e+02       2      10 ..      70      78 ..      69      80 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.2e-05
                E-EEEEEEE..TTEEEEEETT--SHHHHHTTTT-EE CS
        RimM 45 ltvesvrvh..kkgvivklegvddrdaAealkgael 78
                l+ ++++ +   ++ ++k+egvdd++aA  + g ++
  EEA19056.1 16 LSYQRGKRNtnPNTSLIKIEGVDDVSAANFYLGKKV 51
                6666677555699***************98888877 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.063
                EEEEEEEET CS
        RimM  2 vGkIvgahG 10
                 Gk++++hG
  EEA19056.1 70 WGKVTRPHG 78
                59******9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (88 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       260  (0.0145016); expected 358.6 (0.02)
Passed bias filter:                      219  (0.0122148); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.33s 00:00:00.87 Elapsed: 00:00:00.54
# Mc/sec: 489.96
//
Query:       EEA19057.1  [L=510]
Description: glucose-6-phosphate 1-dehydrogenase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   4.9e-114  380.4   0.0   9.3e-114  379.5   0.0    1.4  1  G6PD_C    Glucose-6-phosphate dehydrogenase, C-terminal domai
      2e-61  207.7   0.1    3.5e-61  206.9   0.1    1.4  1  G6PD_N    Glucose-6-phosphate dehydrogenase, NAD binding doma


Domain annotation for each model (and alignments):
>> G6PD_C  Glucose-6-phosphate dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  379.5   0.0    1e-117  9.3e-114       1     289 [.     204     492 ..     204     496 .. 0.97

  Alignments for each domain:
  == domain 1  score: 379.5 bits;  conditional E-value: 1e-117
                 HHHHHS-STTSTTSSTTTEEEEEEEEEESS--TTTHHHHTTTHHHHHTTTTHHHHHHHHHH----SSSSHHHHHHHHHHHHTTB----G...GG.EEEE CS
      G6PD_C   1 lvlRfaNalfeplwnrnyidhvqitvketlgvegrggYydeaGalrDvvqnHllqllalvamepPasldaedirdekvkvLkslrplkleevekkvvrG 99 
                 l+lRf+N++f ++wnr++id+vqit+ke++g+egrggY+de+G++rDv+qnHllq+l+l+ame+P+s++aedirdekv+vL+ +  +++    k+v++G
  EEA19057.1 204 LILRFGNEFFGATWNRHHIDNVQITFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQVLTLLAMERPISFSAEDIRDEKVRVLRGMDAIEP----KNVIIG 298
                 589*************************************************************************************9....459*** PP

                 EE.....E--TGS-STTSTTS-TT----SEEEEEEEB-STTTTT-EEEEEEESSBSS-EEEEEEEE---SS-SS---.--EEEEEEESS-EEEEEEEEE CS
      G6PD_C 100 qYaagavkgkevkgYreeegvakdSkteTfvalkleidnerwagVPfylrtGKrLnekkteiriqfkkvpsdlfkkkerneLviriqpdeaislklnak 198
                 qY  g + + ++++Y+e+++v+kdS++ Tf+a++++i+nerw+gVPf+l++GK+Lne+kte+riqfk+v+s +fk+  rneLvir+qp+e++++k+n+k
  EEA19057.1 299 QY--GRSLDGSKPAYKEDDTVPKDSRCATFCAMVAFIKNERWDGVPFILKAGKALNEQKTEVRIQFKDVTSGIFKDIPRNELVIRVQPNESVYIKMNSK 395
                 **..88888999**************************************************************6666********************* PP

                 -SSSE.....EEEEEEHHHHTT...---HHHHHHHHHHHT-GTTSB-HHHHHHHHHHHHHHHHHHHH...---EEEETTSSS-HHHHHHHHHHTX.X CS
      G6PD_C 199 kpgleleleeveldlsykerfk...lpeaYerLlldvlkgdqtlFvrsdeveaaWkivdpileawee...eklekYeagsrgPeeadellekdgrkw 289
                  pgl++++  +eldl+y++rf+   +peaYe+L+ld+lkgd+++Fvr+de++a+W+i++p+l+++++     +++Y++gsrgP+  d++ ++ g+++
  EEA19057.1 396 LPGLSMQTVVTELDLTYRRRFSdlkIPEAYESLILDALKGDHSNFVRDDELDASWRIFSPLLHYLDDnkeIIPMEYPYGSRGPAVLDDFTSSFGYQF 492
                 *******************999999****************************************989885699**************999988775 PP

>> G6PD_N  Glucose-6-phosphate dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  206.9   0.1   3.9e-65   3.5e-61       1     177 []      25     202 ..      25     202 .. 0.95

  Alignments for each domain:
  == domain 1  score: 206.9 bits;  conditional E-value: 3.9e-65
      G6PD_N   1 vifGasGdLakrkllPaLyelaregllpeevrivgvarsklsdeefrekvkealkkekekeeldeekleeflkrleyvsgdleeeeeyekLkekleele 99 
                 v++GasGdLak+k++PaL+ l+r+++lp++++ivg+ar+k++++e+ ++vk+++k  ++     ee+le+f++ ++yvsg+++++e++ +L+++lee e
  EEA19057.1  25 VVLGASGDLAKKKTFPALFGLYRNKFLPKDIKIVGYARTKMDHAEYLRRVKSYIKVPTK---EMEEQLESFCSLCTYVSGQYDQDESFINLNNHLEEIE 120
                 89****************************************************65443...3579*******************************99 PP

      G6PD_N 100 .....anrlfYlavppslfeevaeklkkaglakeeewkrvvvEKPfGkdlesarelneelkkvfkeeqiyrIDhYLGketvqN 177
                      +nr+fY+a+pps+f +v+++lk++ +  +++ +r++vEKPfGkdl s+rel+++l+  +kee+i+rIDhYLGke+v+N
  EEA19057.1 121 kgrkdQNRIFYMALPPSVFITVSDQLKRN-CYPKNSIARIIVEKPFGKDLGSSRELQKALEPNWKEEEIFRIDHYLGKEMVKN 202
                 776666**********************7.6667999*********************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (510 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       557  (0.031067); expected 358.6 (0.02)
Passed bias filter:                      525  (0.0292822); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.70u 0.36s 00:00:01.06 Elapsed: 00:00:00.55
# Mc/sec: 2799.79
//
Query:       EEA19058.1  [L=502]
Description: glucose-6-phosphate 1-dehydrogenase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   4.6e-114  380.5   0.0   8.9e-114  379.6   0.0    1.4  1  G6PD_C    Glucose-6-phosphate dehydrogenase, C-terminal domai
    1.9e-61  207.8   0.1    3.4e-61  206.9   0.1    1.4  1  G6PD_N    Glucose-6-phosphate dehydrogenase, NAD binding doma


Domain annotation for each model (and alignments):
>> G6PD_C  Glucose-6-phosphate dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  379.6   0.0  9.9e-118  8.9e-114       1     289 [.     196     484 ..     196     488 .. 0.97

  Alignments for each domain:
  == domain 1  score: 379.6 bits;  conditional E-value: 9.9e-118
                 HHHHHS-STTSTTSSTTTEEEEEEEEEESS--TTTHHHHTTTHHHHHTTTTHHHHHHHHHH----SSSSHHHHHHHHHHHHTTB----G...GG.EEEE CS
      G6PD_C   1 lvlRfaNalfeplwnrnyidhvqitvketlgvegrggYydeaGalrDvvqnHllqllalvamepPasldaedirdekvkvLkslrplkleevekkvvrG 99 
                 l+lRf+N++f ++wnr++id+vqit+ke++g+egrggY+de+G++rDv+qnHllq+l+l+ame+P+s++aedirdekv+vL+ +  +++    k+v++G
  EEA19058.1 196 LILRFGNEFFGATWNRHHIDNVQITFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQVLTLLAMERPISFSAEDIRDEKVRVLRGMDAIEP----KNVIIG 290
                 589*************************************************************************************9....459*** PP

                 EE.....E--TGS-STTSTTS-TT----SEEEEEEEB-STTTTT-EEEEEEESSBSS-EEEEEEEE---SS-SS---.--EEEEEEESS-EEEEEEEEE CS
      G6PD_C 100 qYaagavkgkevkgYreeegvakdSkteTfvalkleidnerwagVPfylrtGKrLnekkteiriqfkkvpsdlfkkkerneLviriqpdeaislklnak 198
                 qY  g + + ++++Y+e+++v+kdS++ Tf+a++++i+nerw+gVPf+l++GK+Lne+kte+riqfk+v+s +fk+  rneLvir+qp+e++++k+n+k
  EEA19058.1 291 QY--GRSLDGSKPAYKEDDTVPKDSRCATFCAMVAFIKNERWDGVPFILKAGKALNEQKTEVRIQFKDVTSGIFKDIPRNELVIRVQPNESVYIKMNSK 387
                 **..88888999**************************************************************6666********************* PP

                 -SSSE.....EEEEEEHHHHTT...---HHHHHHHHHHHT-GTTSB-HHHHHHHHHHHHHHHHHHHH...---EEEETTSSS-HHHHHHHHHHTX.X CS
      G6PD_C 199 kpgleleleeveldlsykerfk...lpeaYerLlldvlkgdqtlFvrsdeveaaWkivdpileawee...eklekYeagsrgPeeadellekdgrkw 289
                  pgl++++  +eldl+y++rf+   +peaYe+L+ld+lkgd+++Fvr+de++a+W+i++p+l+++++     +++Y++gsrgP+  d++ ++ g+++
  EEA19058.1 388 LPGLSMQTVVTELDLTYRRRFSdlkIPEAYESLILDALKGDHSNFVRDDELDASWRIFSPLLHYLDDnkeIIPMEYPYGSRGPAVLDDFTSSFGYQF 484
                 *******************999999****************************************989885699**************999988775 PP

>> G6PD_N  Glucose-6-phosphate dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  206.9   0.1   3.8e-65   3.4e-61       1     177 []      17     194 ..      17     194 .. 0.95

  Alignments for each domain:
  == domain 1  score: 206.9 bits;  conditional E-value: 3.8e-65
      G6PD_N   1 vifGasGdLakrkllPaLyelaregllpeevrivgvarsklsdeefrekvkealkkekekeeldeekleeflkrleyvsgdleeeeeyekLkekleele 99 
                 v++GasGdLak+k++PaL+ l+r+++lp++++ivg+ar+k++++e+ ++vk+++k  ++     ee+le+f++ ++yvsg+++++e++ +L+++lee e
  EEA19058.1  17 VVLGASGDLAKKKTFPALFGLYRNKFLPKDIKIVGYARTKMDHAEYLRRVKSYIKVPTK---EMEEQLESFCSLCTYVSGQYDQDESFINLNNHLEEIE 112
                 89****************************************************65443...3579*******************************99 PP

      G6PD_N 100 .....anrlfYlavppslfeevaeklkkaglakeeewkrvvvEKPfGkdlesarelneelkkvfkeeqiyrIDhYLGketvqN 177
                      +nr+fY+a+pps+f +v+++lk++ +  +++ +r++vEKPfGkdl s+rel+++l+  +kee+i+rIDhYLGke+v+N
  EEA19058.1 113 kgrkdQNRIFYMALPPSVFITVSDQLKRN-CYPKNSIARIIVEKPFGKDLGSSRELQKALEPNWKEEEIFRIDHYLGKEMVKN 194
                 776666**********************7.6667999*********************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (502 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       543  (0.0302861); expected 358.6 (0.02)
Passed bias filter:                      515  (0.0287244); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.71u 0.36s 00:00:01.06 Elapsed: 00:00:00.56
# Mc/sec: 2683.20
//
Query:       EEA19059.1  [L=566]
Description: sucrose transport protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    9.3e-12   44.2  11.5    9.3e-12   44.2  11.5    2.3  3  MFS_2       MFS/sugar transport protein
     0.0014   17.5   1.8     0.0029   16.5   1.8    1.6  1  MFS_1_like  MFS_1 like family
  ------ inclusion threshold ------
       0.05   13.5   0.1       0.19   11.7   0.1    1.9  1  Tail_P2_I   Phage tail protein (Tail_P2_I)


Domain annotation for each model (and alignments):
>> MFS_2  MFS/sugar transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.2  11.5   1.6e-15   9.3e-12       8     200 ..      10     211 ..       4     269 .. 0.82
   2 ?   -0.6   0.1     0.061   3.6e+02     175     242 ..     294     361 ..     291     367 .. 0.80
   3 ?   -1.9   0.2      0.15   9.2e+02      19      41 ..     371     393 ..     351     399 .. 0.58

  Alignments for each domain:
  == domain 1  score: 44.2 bits;  conditional E-value: 1.6e-15
       MFS_2   8 aanilsvllatylliFytdvlglsaalvglvllvarlvDaitDpivGtlidktstrwGrrrPwlllsaiilavsiillftppelsqs..........ak 96 
                 ++ +++ +   y ++++ +  gl+ ++ +lv ++  l  +i+ p++G+++d+++ +wGrrrP++l +a+i a  ++ll ++ e+             a+
  EEA19059.1  10 GVSFTWGVEMSYCTPYLLQL-GLTKSRTSLVWIAGPLSGLIIHPLIGVIADRSRSKWGRRRPFMLGGALIVASCLLLLGWTSEVVGWfvhdsekkrrAT 107
                 67788888889999999997.***************************************************99999977777533377888999*999 PP

       MFS_2  97 fiwllvtyillrilytlfeipyvslvp.vltkdydeRtsltsvrsflsvlggvlaail.afllvlilgglkserkgylifaliialLmllgviivvlgt 193
                 +++++++  +++ ++++ + +  sl++ +l   +++  s+ ++r++  ++g+++a i+  + +v  +g+     + +  ++++ a+  +++v i+++ +
  EEA19059.1 108 IAVAVLAIYGVDFAINAAQACCRSLIVdTLPISQQQLGSAWAIRMQ--AIGSLIAYIVgSVDMVTTFGT-RFGDTQFKQMTVVAAIFLIVAVAITSYSV 203
                 99999999**************999863566666677777777765..566666655513445556665.6668889999999999999999999999* PP

       MFS_2 194 kervem.r 200
                 kerv   +
  EEA19059.1 204 KERVLIaA 211
                 **987732 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.061
       MFS_2 175 aliialLmllgviivvlgtkervemrkkekteqkeklslleqlkevfrnraflillllfllaalalgv 242
                 ++i++ +++l+ +++ +g+++ ++  k+ + +++ + ++   l+++ r r+ l  +++ +  ++a+++
  EEA19059.1 294 LVIFSGVTFLSSVLLPFGVRSPDSNSKRANFTSRPPPRMAALLRRFKRVRPTLQTAWFLSHLVFAGTM 361
                 68999999999999999999999988899999999999999999999999998766665554444444 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 0.15
       MFS_2  19 ylliFytdvlglsaalvglvllv 41 
                  +++F+++v g++ a+ g++ ++
  EEA19059.1 371 KFATFLVSVCGIPWAVSGWAPFA 393
                 34456666666666666666555 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   1.8   4.9e-07    0.0029      20     197 ..      20     199 ..      12     362 .. 0.76

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 4.9e-07
  MFS_1_like  20 PYltiylkskglkaseigiitlilpltsilsppiwgvlaDrfgkrkkvvilslllsavlflsllfippskerqeesklevsvaqdvd..aektfwilfl 116
                  Y t yl + gl+ s   ++  + pl  ++  p++gv+aDr++ +    +  +l  a++++s l++         s++   + +d +   + t+++ +l
  EEA19059.1  20 SYCTPYLLQLGLTKSRTSLVWIAGPLSGLIIHPLIGVIADRSRSKWGRRRPFMLGGALIVASCLLLL-----GWTSEVVGWFVHDSEkkRRATIAVAVL 113
                 599**************************************99888855444444443333333333.....111122222222222115667777788 PP

  MFS_1_like 117 lvvlasfflaailvlldaatlkelgedrkdyGr..qrlfGsvGyaifafitGi.lidhysvnllp..ysallyvlaallvisllvv 197
                  +   +f ++a+ +   +++  +l   +++ G    +   ++G  i++++ ++ +++++ + + +  ++++ +v+a++l++++++ 
  EEA19059.1 114 AIYGVDFAINAAQACCRSLIVDTLPISQQQLGSawAIRMQAIGSLIAYIVGSVdMVTTFGTRFGDtqFKQMTVVAAIFLIVAVAIT 199
                 88889999999999999999999966666666522566788888888877766466666666655887777777777777777663 PP

>> Tail_P2_I  Phage tail protein (Tail_P2_I)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.1   3.2e-05      0.19      37      69 ..      80     112 ..      75     158 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 3.2e-05
   Tail_P2_I  37 aelLpwLAwelsvdgWdeawseeakRavikeai 69 
                 a++L +L+w  +v gW  + se+++Ra i+ a+
  EEA19059.1  80 ASCLLLLGWTSEVVGWFVHDSEKKRRATIAVAV 112
                 78999************************6654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (566 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       537  (0.0299515); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.73u 0.33s 00:00:01.06 Elapsed: 00:00:00.53
# Mc/sec: 3193.55
//
Query:       EEA19060.1  [L=274]
Description: hypothetical protein PMAA_013240 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (274 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       269  (0.0150036); expected 358.6 (0.02)
Passed bias filter:                      257  (0.0143343); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.58u 0.36s 00:00:00.94 Elapsed: 00:00:00.56
# Mc/sec: 1480.72
//
Query:       EEA19061.1  [L=236]
Description: ThiJ/PfpI family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.5e-13   50.2   0.0    5.8e-13   49.0   0.0    1.6  1  DJ-1_PfpI  DJ-1/PfpI family
    2.1e-09   37.4   0.0    1.8e-08   34.3   0.0    2.0  1  ThiJ_like  ThiJ/PfpI family-like


Domain annotation for each model (and alignments):
>> DJ-1_PfpI  DJ-1/PfpI family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.0   0.0   6.4e-17   5.8e-13      15     162 ..      28     230 ..      22     233 .. 0.71

  Alignments for each domain:
  == domain 1  score: 49.0 bits;  conditional E-value: 6.4e-17
                 HHHHHHHHHHHTTEEEEEEESS................TSEEEETTS....EEEE-SEEGGGCTCC..G-SEEEE--BHHHHHHHHTSHHHHHHHHHHH CS
   DJ-1_PfpI  15 Elivpvdvlkragikvdvvsvd................keevkgsrG....lkvtvdaslddvkaa..eyDalvlpGGragperlrenekvvelvkefa 91 
                 E+  p++vl +ag++++++s++                + e+  s +       + ++ l d+ +   e+Da+  +GG+    +l+ ++  ++l+++fa
  EEA19061.1  28 EFAHPWKVLHEAGVDLTIASPKggeapldpssvelfksD-EIAVSFHknqeSLWKNTVRLADIVPRahEFDAIFYVGGHGPMFDLVSDPISLSLIQTFA 125
                 8999******************99888887777777741.33222221222334445555588665569***********889**************** PP

                 HTT-EEEEETTTHHHHHHTT......TTTTSEE--SGGGHHHH................HHTTSEE-SS......SEEEETT......EEEESSGGGHH CS
   DJ-1_PfpI  92 ekgklvaaICagpqlLaaag......vlkgrrvTsypavkdkl................ekagakyvdk......rvvvdgn......lvTsrgpgaai 156
                 +++k+v a+C+gp++L++a       +l+  +vT++ + +++l                  +ga+yv        +vvvd+       l+T ++p +a 
  EEA19061.1 126 SAKKPVSAVCHGPIVLVNATtpsgepLLRDAKVTGFSNTEEDLaqmtsampflledrlrAIPGATYVKAnepwgvKVVVDKTyqlggvLITGQNPASAT 224
                 *****************986344444788899*****99999966554444444444444444444444777777777776555555567777776666 PP

                 HHHHHH CS
   DJ-1_PfpI 157 efalel 162
                   + el
  EEA19061.1 225 GVGMEL 230
                 555555 PP

>> ThiJ_like  ThiJ/PfpI family-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.3   0.0     2e-12   1.8e-08       4     157 ..      22     180 ..      20     209 .. 0.78

  Alignments for each domain:
  == domain 1  score: 34.3 bits;  conditional E-value: 2e-12
   ThiJ_like   4 eGydvtevaipwkvlkdagfsveFvtekgkvpkadekllsgikakllgas..keakdiYkelstleeFkeplslssesFsleeydlvllpGGsdkavre 100
                 +G+   e a pwkvl++ag+  + +++kg  +  d + ++ +k+  ++ s  k++ +++k+ + l++              +e+d+++  GG++++  +
  EEA19061.1  22 TGWYLPEFAHPWKVLHEAGVDLTIASPKGGEAPLDPSSVELFKSDEIAVSfhKNQESLWKNTVRLAD---------IVPRAHEFDAIFYVGGHGPMF-D 110
                 6888999***********************9999999888777654443311455556666555555.........4445579*************9.* PP

   ThiJ_like 101 lleserlhsllveylklvkrekepskvlgaicqgvlalafakpe....................ldlktttlPlwme 157
                 l+ +++  sl++ +        + +k ++a+c+g ++l +a+++                    l   t+++P  +e
  EEA19061.1 111 LVSDPISLSLIQTFA-------SAKKPVSAVCHGPIVLVNATTPsgepllrdakvtgfsnteedLAQMTSAMPFLLE 180
                 **************9.......67999***************99899998777777777777554455666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (236 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       290  (0.0161749); expected 358.6 (0.02)
Passed bias filter:                      287  (0.0160076); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.33s 00:00:00.94 Elapsed: 00:00:00.55
# Mc/sec: 1294.12
//
Query:       EEA19062.1  [L=1084]
Description: SNF2 family helicase/ATPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.4e-52  178.6   0.2    2.4e-52  177.8   0.2    1.3  1  SNF2_N           SNF2 family N-terminal domain
    1.1e-19   70.9   0.1    7.9e-19   68.0   0.0    2.4  2  Helicase_C       Helicase conserved C-terminal domain
    8.2e-10   38.9   0.1    3.9e-09   36.7   0.0    2.1  2  ResIII           Type III restriction enzyme, res subunit
    3.9e-05   23.0   0.1    3.9e-05   23.0   0.1    1.7  2  ERCC3_RAD25_C    ERCC3/RAD25/XPB C-terminal helicase
  ------ inclusion threshold ------
      0.056   13.4   0.2       0.22   11.5   0.0    2.1  2  HIGH_NTase1_ass  Cytidyltransferase-related C-terminal region
      0.062   13.3   1.8        2.6    8.0   0.0    3.1  2  FGAR-AT_N        Formylglycinamide ribonucleotide amidotransf
      0.064   13.5   0.3       0.32   11.3   0.0    2.3  2  HHH_3            Helix-hairpin-helix motif


Domain annotation for each model (and alignments):
>> SNF2_N  SNF2 family N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  177.8   0.2   9.5e-56   2.4e-52      53     317 ..     562     813 ..     554     851 .. 0.83

  Alignments for each domain:
  == domain 1  score: 177.8 bits;  conditional E-value: 9.5e-56
                 HTT--EEE---TTS--HHHHHHHHH...HHTTTS---.......S-EEEE--HHHHHHHHHHHHHH-TTS-EEE--SSHHHH----------------- CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      SNF2_N  53 qsvrGGiLaDemGLGKTvqvlalilaqrakeekdkekkrkdtlagptLivvPaslldqWeneierhvsssalrvlvyggqkkmkkkntkvapklladyd 151
                 ++   +iLaD+mGLGKT qv+a+++++ +           + + gp+LivvPas++++W +e++++++s ++  ++ ++q+  + + +   ++  ++ +
  EEA19062.1 562 HKKLSCILADDMGLGKTFQVIAFLAHLFE-----------QGITGPHLIVVPASTIENWLREFNKFCPSLNVMPYYAKQQE--RAEIRLAIEDDIENVN 647
                 67789********************3322...........34679*************************99888888876..55556889999***** PP

                 EEEE-HHHHHHHT......TTS-S-S-SEEEES-GGGT--TTSHHHHHHHH---S-EEEE-S--SSS-HHHHHHHHHHH-TTTT--.HHHHHHHTHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxx RF
      SNF2_N 152 vvittYdvlsreaelqkkrsvlkqvewkrvvlDEghtlknstskaaeavskLstsnrwiltGTPiqnsledlygLlkfLreepfge.kqtfdkllqrpi 249
                 v+ittY v + +         l ++     v DEgh lkns+sk++  + ++ ++ r++ltGTP+qn+l++l++Ll f+ +++f++ k+  ++ +++++
  EEA19062.1 648 VIITTYTVAKAKD----DSRFLRNLGFCVCVFDEGHVLKNSESKIYDQLVRIPAEFRLLLTGTPLQNNLQELVSLLGFMLPDVFNKhKEDLQTIFTQKA 742
                 ********99665....456666666666677******************************************************6669999999999 PP

                 H.........HHHHHHHHHHHTT-STTEE---GGGT--S---EEEEEEEEE--HHHHHHHH................ CS
                 x.........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      SNF2_N 250 e.........aqaekgrsrLlqllqrlmlrrakkdveknlPpkteeiiflklskverksYnrllevlrkkalakllk 317
                 +           + ++++r ++++++++lrr k +v ++lP k+ ++ ++++++ ++++Y++  e  rk        
  EEA19062.1 743 KatdtaehaaLLSAQRIARARSMISPFVLRRKKHQV-IDLPAKISRVEYCEMNETQKEIYQEENEEVRKLL-----L 813
                 97777776655566666777788889**********.************************5555444433.....3 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0      0.76     2e+03      15      61 ..     644     691 ..     606     705 .. 0.72
   2 !   68.0   0.0   3.1e-22   7.9e-19       2     111 .]     910    1022 ..     909    1022 .. 0.96

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.76
                 TTSEEEEEESSHHHHHHHHHHHHHTTSTEEEEST.TSTHHHHHHHHHH CS
  Helicase_C  15 eggkilifvntidrlekvklllekkgikvavlhg.elpqnereeileq 61 
                 e+ +++i + t+ ++++ + +l++ g+ v+v++     +n+  +i +q
  EEA19062.1 644 ENVNVIITTYTVAKAKDDSRFLRNLGFCVCVFDEgHVLKNSESKIYDQ 691
                 455677777777777664555455688888887535666666666665 PP

  == domain 2  score: 68.0 bits;  conditional E-value: 3.1e-22
                  HHHHHHHHH.HHTTTTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHH.TTSSS.EEEESGGGTSSSTSTTESEEEESSSSS CS
  Helicase_C    2 kleallell.kleeeggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfn.kgesd.vLiatdvaerGidipkvnlVinfdlpr 95  
                  k+++l+ell k++e+g+++lif++++  ++ ++++le+ ++++ +l+g+++ ++r+ il++f  + e+  ++++t++++ Gi++ ++n Vi+fd  +
  EEA19062.1  910 KVDKLCELLkKFKENGDRTLIFSQFTLVMDILEYVLETINMRFFRLDGRTNVEDRQSILDAFYeQTEIPvFMLSTKAGGAGINLACANKVIIFDSSF 1006
                  7899*****9*****************99889******************************8678888999************************* PP

                  SHHHHHHHHTTSSSTT CS
  Helicase_C   96 nvtsyiqriGRtgRag 111 
                  n+++ +q+  R++R+g
  EEA19062.1 1007 NPQEDVQAENRAHRVG 1022
                  **************87 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.2      0.93   2.4e+03      46      96 ..     218     267 ..     212     318 .. 0.56
   2 !   36.7   0.0   1.5e-12   3.9e-09       4     169 ..     546     707 ..     543     709 .. 0.79

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.93
                 HHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B-- CS
      ResIII  46 erllkkgkeekflflvprkslleqtleefkkflseaykeigkkvsgdkkka 96 
                 e ++  +   + l+l p++++ e ++ +f++   + + + +++ +++  ++
  EEA19062.1 218 EDYRMRNFVTRLLVLFPSLTIQEGLK-AFSQNGGNLDRASEQIARQEDLDK 267
                 55555555568999999999998865.677777776654444444333333 PP

  == domain 2  score: 36.7 bits;  conditional E-value: 1.5e-12
                 E-HHHHHHHHHHT......TTSEEEEEESTTSTHHHHHHHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG........GEEEESSS-B--.. CS
      ResIII   4 lreyQeeaienlleklkskrdkrglikmaTGtGKTlvaaklierllkkgkeekflflvprkslleqtleefkkflseayke....igkkvsgdkkka.. 96 
                 l++yQ+  i+ l   +  +++   +++   G GKT+  +++ ++l+++g     l++vp  ++ e +l+ef+kf ++ +      ++++       a  
  EEA19062.1 546 LKNYQIVGINWLSLLF--HKKLSCILADDMGLGKTFQVIAFLAHLFEQGITGPHLIVVPASTI-ENWLREFNKFCPSLNVMpyyaKQQER------Aei 635
                 5567776666555444..577788899999********************99*******9887.88********9987533433222222......234 PP

                 ..........-SEEEEEHHHHHHTH........HHHTTT-SEEEEETGGGTTS...TTTHHHHHT---SEEEEEESS- CS
      ResIII  97 ...kekdstnkkilvttiqsldadseeeeeeseellrdrfdviiiDEaHrlgak..kswreilekfkeavllglTATp 169
                     e d++n ++++tt+  ++a+      +s  l++  f v ++DE H l+ +  k + + l  +++ ++l lT+Tp
  EEA19062.1 636 rlaIEDDIENVNVIITTYTVAKAKD-----DSRFLRNLGFCVCVFDEGHVLKNSesKIYDQ-LVRIPAEFRLLLTGTP 707
                 4666899***********9999999.....77777778899**********9974447777.566699*********9 PP

>> ERCC3_RAD25_C  ERCC3/RAD25/XPB C-terminal helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.3       2.3   5.9e+03     202     231 ..     283     312 ..     276     322 .. 0.57
   2 !   23.0   0.1   1.5e-08   3.9e-05      40     136 ..     905    1007 ..     897    1054 .. 0.79

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 2.3
  ERCC3_RAD25_C 202 eeeeelaystkeeqkellqkvlaakdeeae 231
                    +e++++a ++ ++++++lqk +a+ ++++ 
     EEA19062.1 283 RERMNMAKQNIKSKQKILQKYTANVQRKDV 312
                    444566666667777777776655544433 PP

  == domain 2  score: 23.0 bits;  conditional E-value: 1.5e-08
  ERCC3_RAD25_C   40 vmnpnkfracefLikyhekrgDkiivfsDnvfa...Lkeyakklkkpy..iyGetseaerlkilqkfkknpkvntifls.kvgDtsiDlPeanv 127 
                      mn+ k+  +  L+k  ++ gD+ ++fs        L+ + ++++ ++  + G+t+ ++r++il++f +++++ + +ls k g + i+l  an 
     EEA19062.1  905 WMNSGKVDKLCELLKKFKENGDRTLIFSQFTLVmdiLEYVLETINMRFfrLDGRTNVEDRQSILDAFYEQTEIPVFMLStKAGGAGINLACANK 998 
                     58888886655566666778********965441124445566666663478**************************97899**********9 PP

  ERCC3_RAD25_C  128 liqisshfg 136 
                     +i  +s f 
     EEA19062.1  999 VIIFDSSFN 1007
                     998887765 PP

>> HIGH_NTase1_ass  Cytidyltransferase-related C-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   8.7e-05      0.22     111     163 ..     376     429 ..     360     444 .. 0.82
   2 ?   -4.1   0.1       5.2   1.3e+04      21      50 ..     622     653 ..     618     664 .. 0.63

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 8.7e-05
  HIGH_NTase1_ass 111 npledi.rdeekiletvneldldelldlnlldeklankliekrpyesieeikea 163
                      +p+ed    e k+l+ +n+  +  l+dl   +e +a  +i+ rp+++++ ++ +
       EEA19062.1 376 SPVEDDsEIEKKVLKFINTCTVPALADLAATPEAIATIIIDARPFRTLNAVRAV 429
                      35554438899************************************9988754 PP

  == domain 2  score: -4.1 bits;  conditional E-value: 5.2
  HIGH_NTase1_ass  21 ikPykivdletkevll..edkLeeDnyviasl 50 
                      + Py  ++ e  e+ l  ed +e  n +i++ 
       EEA19062.1 622 VMPYYAKQQERAEIRLaiEDDIENVNVIITTY 653
                      66888888888886542266677777666654 PP

>> FGAR-AT_N  Formylglycinamide ribonucleotide amidotransferase N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   0.0     0.001       2.6      20      62 ..     296     346 ..     282     355 .. 0.67
   2 ?    2.3   0.5     0.062   1.6e+02      61      99 ..     777     815 ..     728     827 .. 0.54

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.001
   FGAR-AT_N  20 leqlLeygdk........leeeeeegelllVvPRlGtiSpWsSkAtdIahn 62 
                  +++L++ ++         ++++++g+ l+  PR+G  S+ +S A +Ia+ 
  EEA19062.1 296 KQKILQKYTAnvqrkdvaEDDSKPKGKRLMRGPRPGATSSEASPAPEIAKP 346
                 333333222223334443445568888*********************985 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.062
   FGAR-AT_N  61 hncgle.kvkRiErgiayvlelkelseeelaalaalLhDr 99 
                 ++ +l  k++R+E       + ke+ +ee++++++lL Dr
  EEA19062.1 777 QVIDLPaKISRVEYCEMNETQ-KEIYQEENEEVRKLLLDR 815
                 344454466666654444333.377777777777777777 PP

>> HHH_3  Helix-hairpin-helix motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00013      0.32       8      51 ..     392     431 ..     390     437 .. 0.91
   2 ?   -2.0   0.1       1.7   4.5e+03      27      41 ..     756     770 ..     755     774 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00013
       HHH_3   8 iNtAsaeeLqklpGlgpklAknIvayReknGpfksreeLlkvkg 51 
                 iNt++++ L+ l+   +++A  I+++R    pf++++    v +
  EEA19062.1 392 INTCTVPALADLAATPEAIATIIIDAR----PFRTLNAVRAVTE 431
                 8**************************....****998887765 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.7
       HHH_3  27 AknIvayReknGpfk 41 
                 A++I ++R    pf 
  EEA19062.1 756 AQRIARARSMISPFV 770
                 9*******9999996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1084 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       685  (0.0382063); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.93u 0.39s 00:00:01.32 Elapsed: 00:00:00.60
# Mc/sec: 5438.53
//
Query:       EEA19063.1  [L=196]
Description: hypothetical protein PMAA_013270 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (196 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       367  (0.0204696); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.49
# Mc/sec: 1196.26
//
Query:       EEA19064.1  [L=446]
Description: tRNA dihydrouridine synthase (Smm1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.7e-44  150.7   0.0    9.9e-44  149.7   0.0    1.5  1  Dus       Dihydrouridine synthase (Dus)


Domain annotation for each model (and alignments):
>> Dus  Dihydrouridine synthase (Dus)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  149.7   0.0   5.5e-48   9.9e-44       2     281 ..      30     332 ..      29     349 .. 0.83

  Alignments for each domain:
  == domain 1  score: 149.7 bits;  conditional E-value: 5.5e-48
                 E---TTTS-HHHHHHHHHTT-S........................SEEEEEEEE.-SSS---HHHHHHH-GGGGGTSCEEEEEE-S-HHHHHHHHHHH CS
         Dus   2 laPmagvtdlpfRelvrefgat........................aLvvtemvt.akaivreekvrirmlseeeeetplavQlggsdpallaeaAklv 75 
                 laPm++  +lp R +  ++ga+                        ++ +t + + + + v +++++i +++ e+e+ +l++Q+g+++p+l+++aAk+v
  EEA19064.1  30 LAPMVRSGELPSRLIALKYGADlvwgpetidkaimgaerrvnprnnTIEFTRIPSnSSKGVDPKESVIYRIDPENEKGKLIFQIGTASPELAVQAAKVV 128
                 7888888888888888888888888888888888888888888887777777654256789999999******************************** PP

                 HHTT-SCEEEEESSTTEEETTEEEGGGGGGSHHHHHHHHHHHHCCSSS-EEEEEESESS..TTTC.HHHHHHHHHHCT-SEEEEESS.ECCCTT-C..G CS
         Dus  76 adlgadeIdlNvGCPskkvtrggaGaaLlrkpdlvaqivkavvkaveiPvtvkirigid..deeenalelakiveaaGaqaltvHgR.traqnyeg..t 169
                 a  ++ +Id+N GCP++++t+gg+GaaLlr+pd + +i++a+v+ v+ P  + i+++i+  ++ e++  l+ ++ a+G++ lt+H+R t+++ +e   +
  EEA19064.1 129 AG-DVAGIDVNSGCPKPFSTSGGMGAALLRTPDKLVSILEALVREVGTPYKIGISVKIRlfSDPEETKALVTRLVATGITGLTIHCRtTPMRPRERaiR 226
                 *9.********************************************77655555555555446667889*****************877887777779 PP

                 --CHHHHHHHHH-SS-EEEESS--SHHHHHHHHHHH--SEEEESCHHCCSTTHHHHHHHHHHSC------HHHHHHHHHHHHHHCHHTTCCCCCCHHHH CS
         Dus 170 adweaIkevkqavsipviaNGdIkdaedaqaileetGadgvmigrgalgnPwlfaestavktgeaepapplaeeaeiveehlkkleeelgedkglrkir 268
                  +++ I+ v+++  +  ++NGd++++++a + ++e  +dg mi+  a+ n   f+   +++ g    ++ ++e+     + + ++e+++g+ k+l +++
  EEA19064.1 227 EQLSMIATVCREAGVACVMNGDVTSRDQALELMKEYNVDGAMIATSAEANSSCFR--SEADGGLLPWRDVVREY----VKEAIRVENRFGNTKYLLNMM 319
                 9*****************************************************8..45666666666665554....334456777777777777777 PP

                 HHHHHHHHHHTTT CS
         Dus 269 khlawylkglkka 281
                  + ++  +g++k+
  EEA19064.1 320 IKAKDKASGQAKQ 332
                 7777777764444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (446 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       411  (0.0229238); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.49
# Mc/sec: 2752.05
//
Query:       EEA19065.1  [L=418]
Description: hypothetical protein PMAA_013290 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-13   50.0  15.0    0.00023   21.0   1.6    3.3  3  PAN_1     PAN domain
     0.0049   17.1   7.0       0.16   12.2   0.4    3.3  3  MANEC     MANEC domain
  ------ inclusion threshold ------
      0.012   15.8   0.0      0.021   15.1   0.0    1.3  1  TrbC      TrbC/VIRB2 family
      0.013   15.3   0.0      0.029   14.2   0.0    1.5  1  G6B       G6B family


Domain annotation for each model (and alignments):
>> PAN_1  PAN domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.9   1.1e-06    0.0047      18      63 ..      60     102 ..      42     121 .. 0.74
   2 !   20.3   0.4   9.1e-08   0.00041      21      65 ..     171     218 ..     166     234 .. 0.84
   3 !   21.0   1.6   5.2e-08   0.00023      12      66 ..     260     318 ..     248     336 .. 0.80

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 1.1e-06
                 EEECSSHHHHHHHHH.HSTTS--SEEEEETTTTEEEEEESSSSSCSS CS
       PAN_1  18 titvdsaeeCaerCs.eekkfrCrsftfnnstkeCylksedktsltp 63 
                 t+++ s ++C+ +Cs  ++   C  +t+++++ +C +k e  +s+ +
  EEA19065.1  60 TTEA-SISDCMDQCSwYQPA--CYGVTYYTQNETCSFKGEGVNST-M 102
                 3355.99********55565..****************9998883.3 PP

  == domain 2  score: 20.3 bits;  conditional E-value: 9.1e-08
                 CSSHHHHHHHHHHSTTS--SEEEEETT....TTEEEEEESSSSSCSSEE CS
       PAN_1  21 vdsaeeCaerCseekkfrCrsftfnns....tkeCylksedktsltprl 65 
                 +d+++eC+e+C++ +   C+ +++n++     ++Cylk ++ ++lt++ 
  EEA19065.1 171 TDTMSECMELCAHAHP-LCLGVSWNSDlsegYGNCYLKNSQNGTLTSET 218
                 789*********8884.9***********************99975443 PP

  == domain 3  score: 21.0 bits;  conditional E-value: 5.2e-08
                 ESEEEEEEECSSHHHHHHHHHHSTTS.--SEEEEETT....TTEEEEEESSSSSCSSEEE CS
       PAN_1  12 sgedkktitvdsaeeCaerCseekkf.rCrsftfnns....tkeCylksedktsltprlt 66 
                  ++++ ++  ++ +eC  +C+ ++++  C+++ ++ns      +Cyl   ++t + + l+
  EEA19065.1 260 GSSNITSVYSANITECINECATHNGTdSCLAVFYDNSfadgFDNCYLLNATGTET-APLN 318
                 34555666777**********999999**************9**********994.3333 PP

>> MANEC  MANEC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.2      0.16   7.3e+02      35      50 ..      64      80 ..      50      99 .. 0.62
   2 !    6.1   0.1    0.0029        13      31      71 ..     169     209 ..     164     226 .. 0.82
   3 !   12.2   0.4   3.6e-05      0.16      26      72 ..     262     310 ..     254     320 .. 0.80

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.16
       MANEC 35 seedCveaC.csekkCn 50
                s +dC+ +C + +++C 
  EEA19065.1 64 SISDCMDQCsWYQPACY 80
                55677777744455553 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.0029
       MANEC  31 aeveseedCveaCcsekkCnlavveekkeeekkksCyLfnC 71 
                 +++++ ++C+e+C + +   l v  +++ +e   +CyL n 
  EEA19065.1 169 PHTDTMSECMELCAHAHPLCLGVSWNSDLSEGYGNCYLKNS 209
                 6778999*******997777888888888999*****9765 PP

  == domain 3  score: 12.2 bits;  conditional E-value: 3.6e-05
       MANEC  26 kflesaeveseedCveaCcse...kkCnlavveekkeeekkksCyLfnCl 72 
                 + ++s + ++ ++C++ C ++   ++C lav+  ++ ++  ++CyL+n +
  EEA19065.1 262 SNITSVYSANITECINECATHngtDSC-LAVFYDNSFADGFDNCYLLNAT 310
                 556677888899*******99775666.777777777**********975 PP

>> TrbC  TrbC/VIRB2 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.1   0.0   4.6e-06     0.021      43      74 ..     340     371 ..     315     379 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 4.6e-06
        TrbC  43 qnivdfltgplakviatiaiivaGimlafgrl 74 
                  +  +++ gp++ ++a ++i+++G+ ++ +r+
  EEA19065.1 340 SSNKSWIAGPVVGAVAALIIVALGFLWWKRRT 371
                 5556899*********************9986 PP

>> G6B  G6B family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   6.4e-06     0.029     106     160 ..     326     380 ..     318     404 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 6.4e-06
         G6B 106 lgdradCkasgptsGssysqllipllgaglalglgalGvawwlrrrsppallrpl 160
                   d+++  +s+++s s+ s +  p++ga+ al ++alG+ ww+rr+   + ++  
  EEA19065.1 326 SSDNSSADSSSSNSSSNKSWIAGPVVGAVAALIIVALGFLWWKRRTGRQQDVKFA 380
                 56888888999999999***************************98776665544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (418 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       830  (0.0462937); expected 358.6 (0.02)
Passed bias filter:                      563  (0.0314016); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.64u 0.27s 00:00:00.91 Elapsed: 00:00:00.48
# Mc/sec: 2595.35
//
Query:       EEA19066.1  [L=488]
Description: inorganic diphosphatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.5e-57  193.9   0.1      2e-57  193.5   0.1    1.2  1  Pyrophosphatase  Inorganic pyrophosphatase


Domain annotation for each model (and alignments):
>> Pyrophosphatase  Inorganic pyrophosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  193.5   0.1   1.1e-61     2e-57       1     160 []     246     428 ..     246     428 .. 0.97

  Alignments for each domain:
  == domain 1  score: 193.5 bits;  conditional E-value: 1.1e-61
                      EEEEE-TTCSEEEEEETTT...........TEEEEEEE-SSSB-BSSEEEEETT--BT.......CCBEETSSSEEEEEESSS---TTEEEEEE CS
  Pyrophosphatase   1 vvvEiprgsnaKyeidkee...........gklrldrvlftskgypanYGfipqTled.......telkGDgDPlDvlvlgeeplspgevvevk 76 
                      ++vEipr++naK ei+kee           gklr++r++f++kgy +nYG++p+T+ed       t++kGD+DPlDv+++ge   ++g+v++vk
       EEA19066.1 246 MIVEIPRWTNAKQEISKEEflnpikqdtkkGKLRFVRNCFPHKGYLWNYGAFPRTWEDpnvvhpeTKAKGDNDPLDVCEIGELVGYTGQVKQVK 339
                      89*******************************************************************************9999********* PP

                      EEEEEEEEETTEEEEEEEEEETTSGGGTT-SSGGG....STHHHHHHHHHHHHHTTTTSCCT-SE.EEE.EEEEHHHHHHHHHHHHHHHH CS
  Pyrophosphatase  77 vlGvlamiDegetDdKiiavpvkdprlkkindied....lpgllleeiehfFetykdlegkkknv.kve.ewkdkeeAekvieeaheryk 160
                      vlGv+a++De+etD+Kii+++v+dp   k+ndied    lpgll ++++++F+ yk+++gk +n+ +++ e+k+k++Ae+vi+e++++++
       EEA19066.1 340 VLGVMALLDEEETDWKIIVIDVNDPLAPKLNDIEDverhLPGLL-RATNEWFRIYKIPDGKPENQfAFSgECKNKKYAEEVIRECADAWE 428
                      *************************779*******998888888.***************966888*********************995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (488 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       455  (0.0253779); expected 358.6 (0.02)
Passed bias filter:                      426  (0.0237604); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.24s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 3382.26
//
Query:       EEA19067.1  [L=154]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.5e-15   55.3   0.1    1.3e-14   54.1   0.1    1.7  1  MRP_L53   39S ribosomal protein L53/MRP-L53


Domain annotation for each model (and alignments):
>> MRP_L53  39S ribosomal protein L53/MRP-L53
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.1   0.1   7.1e-19   1.3e-14       1      53 []      63     118 ..      63     118 .. 0.99

  Alignments for each domain:
  == domain 1  score: 54.1 bits;  conditional E-value: 7.1e-19
     MRP_L53   1 FnPFspnaksaRlFLsll...skppaarnpgckiktkvlpdastseptvkVtFkDG 53 
                 F+PFsp  +++R +L+ll   s+ p++++++++ik+ +lp++st+ p+ +++Fk+G
  EEA19067.1  63 FSPFSPLGRPCRILLNLLqnpSTAPTSSATHIDIKVSHLPRNSTQLPECTIGFKGG 118
                 9*****************************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (154 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       380  (0.0211947); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.46
# Mc/sec: 1006.09
//
Query:       EEA19068.1  [L=383]
Description: protein transport membrane glycoprotein Sec20, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.8e-17   62.0   6.4    8.6e-17   60.8   1.5    2.8  3  Sec20     Sec20
  ------ inclusion threshold ------
      0.017   15.5   1.9      0.047   14.1   1.9    1.8  1  DUF3510   Domain of unknown function (DUF3510)
       0.14   12.6   3.3          1    9.8   0.2    3.2  2  V-SNARE   Vesicle transport v-SNARE protein N-terminus
       0.85    8.9   5.0        3.5    6.9   0.3    2.5  2  CorA      CorA-like Mg2+ transporter protein
       0.87    9.8   4.4         10    6.3   4.4    2.4  1  CUT       CUT domain


Domain annotation for each model (and alignments):
>> Sec20  Sec20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.0     0.033   1.2e+02      37      64 ..       3      30 ..       1      34 [. 0.88
   2 !   60.8   1.5   2.4e-20   8.6e-17       3      92 .]     165     254 ..     163     254 .. 0.98
   3 ?   -3.0   0.0       1.9   6.9e+03      39      59 ..     327     347 ..     323     350 .. 0.59

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.033
       Sec20 37 slekleeeykqvedvlsrskklvkkler 64
                +l++l++ +k++++ l+ +k l+  l +
  EEA19068.1  3 TLHALQSRLKETSNALNETKPLIDRLRN 30
                68999******************98876 PP

  == domain 2  score: 60.8 bits;  conditional E-value: 2.4e-20
       Sec20   3 akqiTeslraisqllsqevqqSeenleeldastkslekleeeykqvedvlsrskklvkklerrdktdkllvflalglflacvvyvvkkRi 92 
                 ++++T++lr+ ++l+++e  +S+ + e+l++st  l +l+e y ++++vls ++ lv++l r++k+d   +  ++ l++ ++ ++v++R+
  EEA19068.1 165 SSDVTAALRRTHELMQAELSRSQFAQETLEQSTAALSSLSESYANLDSVLSSTRTLVSSLLRSQKSDTWYLETSFYLLIGTIAWLVFRRL 254
                 789**************************************************************************************7 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 1.9
       Sec20  39 ekleeeykqvedvlsrskklv 59 
                 e+++++ k+ ++vl + +++v
  EEA19068.1 327 EQISDDIKDEDSVLDKINEMV 347
                 556666666666666665555 PP

>> DUF3510  Domain of unknown function (DUF3510)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   1.9   1.3e-05     0.047      22      98 ..     154     230 ..     109     236 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 1.3e-05
     DUF3510  22 RrtnkevptepSkyvseilkplktf.kkesekk.lseevleewlaevleevtsrYletisevlssvkkteesLkrlkka 98 
                 + t+ +v+ ++S+ v+ +l+ ++++ ++e +++ + +e+le   +++l++++++Y++ ++ vlss++   +sL r +k 
  EEA19068.1 154 KFTQNDVVVNASSDVTAALRRTHELmQAELSRSqFAQETLE-QSTAALSSLSESYAN-LDSVLSSTRTLVSSLLRSQKS 230
                 56788899****************64555555558888755.567899*********.899************998876 PP

>> V-SNARE  Vesicle transport v-SNARE protein N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.2   0.00029         1      18      60 ..      37      79 ..      15      84 .. 0.82
   2 ?    1.7   0.2     0.093   3.3e+02      17      67 ..     190     229 ..     163     239 .. 0.53

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00029
     V-SNARE 18 lageerkaalreiekkldeaeelldqMelEvrnlpsserasyk 60
                + +e r ++ +ei+++l+ +e+ ++ +++Ev++l  ++ ++ k
  EEA19068.1 37 QGDEARLELGAEIHSRLKHVEDDIEILNVEVQGLEVATSQQSK 79
                5448999***************************665555555 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.093
     V-SNARE  17 slageerkaalreiekkldeaeelldqMelEvrnlpsserasykaklreyk 67 
                 +++ e+  aal+ + ++  +++++l+           s+r+ +++ lr+ k
  EEA19068.1 190 QETLEQSTAALSSLSESYANLDSVLS-----------STRTLVSSLLRSQK 229
                 22235555555555555555555544...........44444444444444 PP

>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.3   0.00098       3.5     152     226 ..       3      78 ..       1      82 [. 0.84
   2 ?    3.5   0.4      0.01        37     141     180 ..     183     227 ..     155     243 .. 0.60

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.00098
        CorA 152 elaqlrrrlvklrralapnrevlkrlla.kaddkllddedkeylrdlldelerllemlealrerleslqdtyssll 226
                 +l +l+ rl +   al++++ +++rl + ++  ++ d+++ e+  +++++l+++++++e+l   ++ l  + s+++
  EEA19068.1   3 TLHALQSRLKETSNALNETKPLIDRLRNfTHAIGQGDEARLELGAEIHSRLKHVEDDIEILNVEVQGLEVATSQQS 78 
                 67789999***************6555588888899999999999****************999998877766665 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.01
        CorA 141 l.....edstkkeilrelaqlrrrlvklrralapnrevlkrllak 180
                 l      ++t ++    l+ l +++++l ++l+ +r+++++ll++
  EEA19068.1 183 LsrsqfAQETLEQSTAALSSLSESYANLDSVLSSTRTLVSSLLRS 227
                 333333444444555566677777777778888888777777773 PP

>> CUT  CUT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   4.4    0.0029        10      15      45 ..     175     205 ..     162     238 .. 0.78

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0029
         CUT  15 keeLkrasisqavFAekvlnrsqgtlselLr 45 
                 + eL +a+ s++ FA++ l++s   ls l +
  EEA19068.1 175 THELMQAELSRSQFAQETLEQSTAALSSLSE 205
                 469999****************999977754 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (383 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1383  (0.0771376); expected 358.6 (0.02)
Passed bias filter:                      562  (0.0313459); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.58u 0.32s 00:00:00.89 Elapsed: 00:00:00.51
# Mc/sec: 2269.13
//
Query:       EEA19069.1  [L=394]
Description: DNA replication factor C subunit Rfc2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-21   77.1   0.1    2.8e-21   75.7   0.1    1.8  1  Rep_fac_C        Replication factor C C-terminal domain
    4.1e-15   56.4   0.0    1.6e-14   54.5   0.0    2.0  2  AAA              ATPase family associated with various cellul
    8.7e-13   48.4   0.0    1.5e-11   44.3   0.0    2.4  1  DNA_pol3_delta2  DNA polymerase III, delta subunit
    7.9e-09   35.7   0.0    2.4e-08   34.1   0.0    1.9  1  Rad17            Rad17 P-loop domain
    1.4e-05   25.6   0.3    0.00084   19.8   0.0    2.9  3  AAA_16           AAA ATPase domain
    1.7e-05   24.7   0.1     0.0001   22.1   0.0    2.2  3  RuvB_N           Holliday junction DNA helicase RuvB P-loop d
    2.2e-05   24.7   0.1    8.1e-05   22.9   0.1    2.1  1  AAA_assoc_2      AAA C-terminal domain
    9.1e-05   22.8   0.0    0.00034   20.9   0.0    1.9  1  AAA_22           AAA domain
    0.00022   20.7   0.0      0.015   14.7   0.0    2.4  2  Mg_chelatase     Magnesium chelatase, subunit ChlI
    0.00026   20.4   0.0    0.00046   19.5   0.0    1.3  1  DUF2075          Uncharacterized conserved protein (DUF2075)
    0.00031   20.6   0.0    0.00031   20.6   0.0    1.9  2  AAA_11           AAA domain
    0.00055   19.7   0.0     0.0012   18.6   0.0    1.5  1  AAA_24           AAA domain
     0.0011   18.9   0.0     0.0061   16.6   0.0    2.2  2  AAA_5            AAA domain (dynein-related subfamily)
     0.0014   18.6   0.0     0.0033   17.4   0.0    1.6  1  AAA_14           AAA domain
     0.0043   17.4   0.0      0.031   14.6   0.0    2.2  1  AAA_19           AAA domain
     0.0069   15.6   0.0      0.011   14.9   0.0    1.3  1  DUF815           Protein of unknown function (DUF815)
     0.0084   15.9   0.0      0.018   14.8   0.0    1.5  1  DNA_pol3_delta   DNA polymerase III, delta subunit
     0.0085   15.6   0.0      0.015   14.8   0.0    1.4  1  AAA_7            P-loop containing dynein motor region
  ------ inclusion threshold ------
      0.018   14.8   0.0       0.13   12.0   0.0    2.1  2  DEAD             DEAD/DEAH box helicase
      0.024   15.2   0.0      0.094   13.3   0.0    2.0  1  AAA_18           AAA domain
      0.024   14.3   0.0      0.088   12.5   0.0    2.0  1  AAA_30           AAA domain
      0.028   14.3   0.2        0.4   10.6   0.0    2.5  2  AAA_3            ATPase family associated with various cellul
       0.03   14.6   0.0      0.067   13.4   0.0    1.7  1  AAA_28           AAA domain
      0.042   13.9   0.0       0.47   10.4   0.0    2.2  2  ResIII           Type III restriction enzyme, res subunit
       0.12   11.5   0.0        0.2   10.7   0.0    1.3  1  Parvo_NS1        Parvovirus non-structural protein NS1
       0.15   12.6   0.0       0.24   11.9   0.0    1.4  1  AAA_23           AAA domain


Domain annotation for each model (and alignments):
>> Rep_fac_C  Replication factor C C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.7   0.1   4.1e-24   2.8e-21       1      87 [.     297     386 ..     297     387 .. 0.89

  Alignments for each domain:
  == domain 1  score: 75.7 bits;  conditional E-value: 4.1e-24
                 --HHHHHHHHHHHHH....T-HHHHHHHHHHHHHHC---HHHHHHHHHHHGCCS..S-HHHHHHHHHHHHHHHHHHHCTH-HHHHHHHHHH CS
   Rep_fac_C   1 phpteieeileacln....gdfeeaykklrellvekGysaediltqlhrvvkeqeelpeaqkleilellgeiekrlveGasehlqlsalla 87 
                 +++++++++++a+++    + +e++ +++ +++v++G+sa++iltql+r ++ ++ +p+ qk++i+++++e++krl++G++ehl+++++++
  EEA19069.1 297 VPESVLDKLMQAMQPkkmgSAYEAVAAVV-SDIVADGWSATQILTQLYRRIVFNDAIPDIQKNKIVMVFSEMDKRLLDGSDEHLSILDMVL 386
                 6899*********8888844444444445.7*********************9999*********************************97 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.5   0.0   2.3e-17   1.6e-14       1     128 [.      75     205 ..      75     209 .. 0.80
   2 ?   -2.4   0.1       8.4   5.8e+03      52      70 ..     354     370 ..     336     383 .. 0.69

  Alignments for each domain:
  == domain 1  score: 54.5 bits;  conditional E-value: 2.3e-17
                 EEEESSTTSSHHHHHHHHHHHH......THEEEEEETTTCSSSSTTHHHHHHHHHHHH.HHHTS............TS.EEEEEETGGGHHHHHTTCCC CS
         AAA   1 vllyGppGtGKTllakavakel......gvefleisgsellskyvgesekkirelfke.akeka............kp.silfiDEidalaksrsgses 79 
                 +l+yGppGtGKT+++ a+ak+l       +++le+++s+ +   +    +ki+++ ++ +++ +             p +i+++DE+d+++++      
  EEA19069.1  75 MLFYGPPGTGKTSTILALAKSLfgptlyRTRILELNASDER--GINIVREKIKDFARTqLSQPSgldaayrekypcPPfKIIILDEADSMTQDA----- 166
                 89*******************86655556899999999999..555555555555544223333556666667798778***********9888..... PP

                 HHHHHHHHHHHHHHHHTTTSSSTEEEEEEESSGGGSTHHHHSTTSSEEE CS
         AAA  80 eeeervvnqLlteldgvkkkeskvivigatnrpdkldpallrgRfdrki 128
                       +++L + ++++++    + +++++n++ ++ ++l  +R+++  
  EEA19069.1 167 ------QSALRRTMEQYSR---ITRFCLVCNYVTRIIEPLA-SRCSKFR 205
                 ......*************...489****************.9998754 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 8.4
                 HHHHTSTSEEEEEETGGGH CS
         AAA  52 eakekakpsilfiDEidal 70 
                 +++++  + ++++ E+d+ 
  EEA19069.1 354 DIQKN--KIVMVFSEMDKR 370
                 33444..488888888875 PP

>> DNA_pol3_delta2  DNA polymerase III, delta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.3   0.0   2.2e-14   1.5e-11       2     162 ..      56     209 ..      55     210 .. 0.88

  Alignments for each domain:
  == domain 1  score: 44.3 bits;  conditional E-value: 2.2e-14
  DNA_pol3_delta2   2 qeealkilskalksgrlahayLfeGdegigkkelalnlakallceeknetkpcgecksckkieqgkhpDvivi.eteekersikldqireliee 94 
                      q+++ ++l++ l+  +l h +Lf+G+ g+gk ++ l+lak+l+     +t        + +++  +   ++++ e+ + ++  +l q   l + 
       EEA19069.1  56 QDHTTTVLQRTLQASNLPH-MLFYGPPGTGKTSTILALAKSLFGPTLYRT-------RILELNASDERGINIVrEKIKDFARTQLSQPSGLDAA 141
                      6778899***********9.79*********************9999877.......4555555566666666344566778888998999999 PP

  DNA_pol3_delta2  95 lsrkpreskkkiiiiedaekmtksAaNalLktlEEPsenaifiLitsdtnklLktirSRcqelkfspl 162
                        +k      kiii+++a+ mt+ A+ al +t+E  s+ + f L+ +  +++++++ SRc +++f++l
       EEA19069.1 142 YREKYPCPPFKIIILDEADSMTQDAQSALRRTMEQYSRITRFCLVCNYVTRIIEPLASRCSKFRFKAL 209
                      9999999**********************************************************986 PP

>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.1   0.0   3.5e-11   2.4e-08       3      69 ..      35      96 ..      33     197 .. 0.81

  Alignments for each domain:
  == domain 1  score: 34.1 bits;  conditional E-value: 3.5e-11
       Rad17  3 edenelWfekykPekaeelavhkkkieevkewlkadvLesrkkriLLisGPsGCgkstvvkvLskel 69
                + + ++W+eky+P+ ++++a   +    +++ l+a+ L++      L  GP+G gk+ ++  L+k l
  EEA19069.1 35 KARLQPWVEKYRPKSLDDVAAQDHTTTVLQRTLQASNLPHM-----LFYGPPGTGKTSTILALAKSL 96
                56889**********************************98.....99*****************87 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.0   1.2e-06   0.00084      14      51 ..      61      99 ..      54     147 .. 0.75
   2 ?    2.7   0.0      0.21   1.4e+02     135     161 ..     137     176 ..     103     186 .. 0.63
   3 ?   -0.8   0.0       2.5   1.7e+03      64     120 ..     246     302 ..     220     378 .. 0.59

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 1.2e-06
      AAA_16 14 salervrsgrp.elvllsGesGvGKsslvrellralekd 51
                ++l+r+ + +  + +l++G++G+GK+s + +l+++l + 
  EEA19069.1 61 TVLQRTLQASNlPHMLFYGPPGTGKTSTILALAKSLFGP 99
                4566555555559********************998776 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.21
      AAA_16 135 r............p.lvlvlDdlqwadeaslqllaaLlrl 161
                              p  +++lD+++   ++ +++l+ +++ 
  EEA19069.1 137 GldaayrekypcpPfKIIILDEADSMTQDAQSALRRTMEQ 176
                 3666666666665446899999999998888888887765 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 2.5
      AAA_16  64 esaipysa.laqalareellrqlldeaesaeleawrekleealaavpelagaeasrll 120
                 ++ai+y++  a++  + + +++  +++++   ++ + +l + ++ v e+ag  ++++l
  EEA19069.1 246 RRAITYLQsAARLVGATQPVKKDSQDDTEMTDADSAPALIT-VRTVEEIAGVVPESVL 302
                 55566655455555554555555444333222222222222.2223333333333333 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.1   0.0   1.5e-07    0.0001       2      57 ..      46      96 ..      45     105 .. 0.89
   2 ?   -1.8   0.0       3.4   2.3e+03      86     111 ..     152     177 ..     148     180 .. 0.89
   3 ?   -2.2   0.0       4.5   3.1e+03      76     111 ..     336     370 ..     313     373 .. 0.71

  Alignments for each domain:
  == domain 1  score: 22.1 bits;  conditional E-value: 1.5e-07
      RuvB_N  2 rPksleeyigqekvkeklkifieaakkreealdhvllyGpPGlGkttlakiiakel 57
                rPksl++  +q++ ++ l+ +++a+     +l h+l+yGpPG Gkt+    +ak l
  EEA19069.1 46 RPKSLDDVAAQDHTTTVLQRTLQAS-----NLPHMLFYGPPGTGKTSTILALAKSL 96
                9*****************9999986.....699*************9887777765 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 3.4
      RuvB_N  86 dvlfideihrlsraveevlysamedf 111
                 +++ +de   +++ ++  l  +me +
  EEA19069.1 152 KIIILDEADSMTQDAQSALRRTMEQY 177
                 68899******************998 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 4.5
      RuvB_N  76 aalltnleekdvlfideihrlsraveevlysamedf 111
                 + +lt+l +  ++f d i  ++++   +++s m+  
  EEA19069.1 336 TQILTQLYR-RIVFNDAIPDIQKNKIVMVFSEMDKR 370
                 456777754.57788888888887777777777665 PP

>> AAA_assoc_2  AAA C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.1   1.2e-07   8.1e-05       4      41 ..     226     280 ..     223     304 .. 0.75

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 1.2e-07
                  .XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..................X CS
  AAA_assoc_2   4 klkleddalealaeladGDaRkaLnlLElaaeaaeak.................e 41 
                   l+l++ ++e+l+++++GD R+a+++L+ aa+   a+                 +
   EEA19069.1 226 GLTLDEGVVETLIRCSEGDLRRAITYLQSAARLVGATqpvkkdsqddtemtdadS 280
                  5899************************999988776666666644444444333 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.0   4.9e-07   0.00034       7     118 ..      74     176 ..      69     191 .. 0.78

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 4.9e-07
      AAA_22   7 ilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelkaerlsseellealeqalraravielliiDEaqhlrs 105
                 +++ +G++GtGKT ++  l+++l     ++  r ++++ +++ + +   +++++  +   +l+      + l +a ++        +++i+DEa+ + +
  EEA19069.1  74 HMLFYGPPGTGKTSTILALAKSL---FGPTLYRTRILELNASDERGINIVREKIKDFARTQLSQ----PSGLDAAYREKYPCPPF-KIIILDEADSM-T 163
                 6889******************9...34444889989999999998888888888888865555....77777777777777777.***********.7 PP

      AAA_22 106 eealeeLrsllnl 118
                 ++a + Lr+ ++ 
  EEA19069.1 164 QDAQSALRRTMEQ 176
                 7777777776663 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   2.2e-05     0.015       2      58 ..      50     110 ..      49     135 .. 0.74
   2 ?    3.4   0.0     0.062        42     109     146 ..     153     189 ..     152     203 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 2.2e-05
  Mg_chelatase   2 lkdvkGqeeakrale..iaaaGgHnlllvGppGsGKtmlakrlpsll..pplseeealeva 58 
                   l dv+ q+++ ++l+  + a+   ++l++GppG+GKt  + +l++ l  p l ++ +le +
    EEA19069.1  50 LDDVAAQDHTTTVLQrtLQASNLPHMLFYGPPGTGKTSTILALAKSLfgPTLYRTRILELN 110
                   678888998888886336678888************8665555433323666666666665 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.062
  Mg_chelatase 109 vLfLDElpefkrkvlevLRePledgevtisrakakvef 146
                   +++LDE+  +++++  +LR+ +e+ + +i+r    +++
    EEA19069.1 153 IIILDEADSMTQDAQSALRRTMEQYS-RITRFCLVCNY 189
                   689*******************9865.66666655555 PP

>> DUF2075  Uncharacterized conserved protein (DUF2075)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0   6.7e-07   0.00046       7     113 ..      78     174 ..      74     187 .. 0.81

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 6.7e-07
     DUF2075   7 tGvaGtGKtvvllnllaeleddeeertavylsvNhpl..vlvlrealakkeekkkkkeafeklssfinnlsefkkaeekkeepkedvvivDEAhrlltk 103
                  G +GtGKt   l+l+  l    ++rt+++ +   ++  ++++re+++  +     +++++++s +  +++      ek + p+++++i DEA  +++ 
  EEA19069.1  78 YGPPGTGKTSTILALAKSLFGPTLYRTRILELNASDErgINIVREKIKDFA-----RTQLSQPSGLDAAYR------EKYPCPPFKIIILDEADSMTQD 165
                 799****************99999999999887766622579999996666.....999999****99999......999****************995 PP

     DUF2075 104 sdqaekqsee 113
                 +++a ++ + 
  EEA19069.1 166 AQSALRR-TM 174
                 5554433.33 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.6   0.0   4.6e-07   0.00031      12      42 ..      65      97 ..      54     136 .. 0.74
   2 ?   -2.6   0.0       5.5   3.8e+03     217     226 ..     150     159 ..     138     164 .. 0.87

  Alignments for each domain:
  == domain 1  score: 20.6 bits;  conditional E-value: 4.6e-07
      AAA_11 12 salsese..itliqGPPGtgKTktivellsqll 42
                ++l+ s+    l+ GPPGtgKT+ti++l ++l 
  EEA19069.1 65 RTLQASNlpHMLFYGPPGTGKTSTILALAKSLF 97
                455555555589*****************9995 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 5.5
      AAA_11 217 kfdvviIDEA 226
                  f+++i DEA
  EEA19069.1 150 PFKIIILDEA 159
                 699******9 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0   1.7e-06    0.0012       5      93 ..      75     178 ..      72     191 .. 0.69

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 1.7e-06
      AAA_24   5 iliyGpsgiGKTtlakel........gpkplfidtekGlksldadkfpdieswedfldevvel.................aaeladyktlviDtidele 78 
                 +l yGp+g+GKT++++ l         +++ ++ ++++  +  ++          ++++++ +                 +   +++k++++D +d + 
  EEA19069.1  75 MLFYGPPGTGKTSTILALakslfgptLYRTRILELNASDERGINI----------VREKIKDFartqlsqpsgldaayreKYPCPPFKIIILDEADSMT 163
                 789***************777777776666666666655433333..........3333333333334445556655543777789************9 PP

      AAA_24  79 elclaevirqnekae 93 
                 + +   ++r  e  +
  EEA19069.1 164 QDAQSALRRTMEQYS 178
                 999988877666545 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   8.9e-06    0.0061       1      90 [.      74     175 ..      74     182 .. 0.75
   2 ?   -1.6   0.0       3.5   2.4e+03      71      94 ..     290     314 ..     248     327 .. 0.71

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 8.9e-06
                 EEEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--...............--------......G-SEEEEESGGG--HHHHHHHHH CS
       AAA_5   1 dvlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreik......ngttslvdsplvraar......egeilvlDEveraesevlnsLls 87 
                 ++l  GppGtgK++ +  la+ l  +++y      ++++d +g   ++       +t+  ++s l  a r        +i++lDE + + ++++++L +
  EEA19069.1  74 HMLFYGPPGTGKTSTILALAKSLFGPTLYRTRILELNASDERGINIVRekikdfARTQLSQPSGLDAAYRekypcpPFKIIILDEADSMTQDAQSALRR 172
                 6899*******************55554444444444444444433333355778888888888888888999998889*********99999999988 PP

                 HHH CS
       AAA_5  88 lle 90 
                  +e
  EEA19069.1 173 TME 175
                 776 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 3.5
                 EESGGG--.HHHHHHHHHHHHSSEE CS
       AAA_5  71 lDEverae.sevlnsLlslleerrl 94 
                 ++E+  +   +vl++L++ +  +++
  EEA19069.1 290 VEEIAGVVpESVLDKLMQAMQPKKM 314
                 4555554447788888888877777 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.0   4.8e-06    0.0033       6      93 ..      76     180 ..      72     189 .. 0.74

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 4.8e-06
      AAA_14   6 vitGaRrvGKTtllkqlikell...vkkesilyinldderd.............kkladpekllelileklke.ekktylflDEiqev.pewekalksl 86 
                 +  G+  +GKT  +  l+k+l+     + +il++n  der              ++l++p+ l+ +++ek+ + +  ++++lDE+  + +++++al++ 
  EEA19069.1  76 LFYGPPGTGKTSTILALAKSLFgptLYRTRILELNASDERGinivrekikdfarTQLSQPSGLDAAYREKY-PcPPFKIIILDEADSMtQDAQSALRRT 173
                 5679999*************99**99999*********999666554443333222223336666777764.1456789******865378******** PP

      AAA_14  87 vdegknl 93 
                 +++++++
  EEA19069.1 174 MEQYSRI 180
                 9988554 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   4.5e-05     0.031       7      38 ..      69     100 ..      64     187 .. 0.65

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 4.5e-05
      AAA_19   7 alkekvllvtaGpGtGKTrvlkhivallvelg 38 
                 a++ +++l  ++pGtGKT ++ +  + l   +
  EEA19069.1  69 ASNLPHMLFYGPPGTGKTSTILALAKSLFGPT 100
                 7788899**************99998876555 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   1.6e-05     0.011      19     104 ..      42     126 ..      25     132 .. 0.71

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.6e-05
      DUF815  19 veevdevklddLvgidkqkealventeqfleglpannvLLwGarGtGKSslvkallneyaeeg...Lrlievekedlkelpklvellre 104
                 ve++++ +ldd+   d+  + l    ++ l+  +  ++L++G  GtGK s++ al +++   +    r++e++ +d + ++ + e++++
  EEA19069.1  42 VEKYRPKSLDDVAAQDHTTTVL----QRTLQASNLPHMLFYGPPGTGKTSTILALAKSLFGPTlyrTRILELNASDERGINIVREKIKD 126
                 5555555555555555544433....34456677789*********************9999855568999998888887777777776 PP

>> DNA_pol3_delta  DNA polymerase III, delta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   2.7e-05     0.018      59     169 ..     152     252 ..     148     254 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 2.7e-05
                     EEEEEE--.....TT-S-TTHHHHHHHHTTT--SSEEEEEEES.S--HHHHHHHHHTTTEEEEEE----TTTHHHHHHHHHHHTT-EE-HHHHHH CS
  DNA_pol3_delta  59 rivvlknpklltkesklnekllkeLeeylsnlpedtlLiliapkklderkklvklLkkkatvveaktlkeeelkkwiqkraqelglkiekealel 153
                     +i++l+ +      ++ +++ + +L +++++++  t ++l+++      ++++  L+++ + +++k l++    + i+++a+++gl +++ ++e+
      EEA19069.1 152 KIIILDEA------DSMTQDAQSALRRTMEQYSRITRFCLVCN----YVTRIIEPLASRCSKFRFKALDGVSAGDRISEIAAAEGLTLDEGVVET 236
                     56666666......55788899999999999999999999999....456799999999999********************************* PP

                     HHHHHTT-HHHHHHHH CS
  DNA_pol3_delta 154 Llelvennlsaikqel 169
                     L+ ++e++l+++ + l
      EEA19069.1 237 LIRCSEGDLRRAITYL 252
                     *********9987665 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   2.2e-05     0.015      30      70 ..      69     110 ..      53     127 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 2.2e-05
       AAA_7  30 lknkkpvllvGptGtGKtviikdllkkld.kekylsltinfs 70 
                  +n  ++l++Gp GtGKt++i  l k+l  ++ y + +++++
  EEA19069.1  69 ASNLPHMLFYGPPGTGKTSTILALAKSLFgPTLYRTRILELN 110
                 3445689**************998887753555666555555 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0       1.1   7.9e+02      16      32 ..      74      90 ..      58     112 .. 0.80
   2 ?   12.0   0.0   0.00019      0.13     104     153 ..     134     181 ..     106     187 .. 0.79

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 1.1
                EEEEEESTTSSHHHHHH CS
                xxxxxxxxxxxxxxxxx RF
        DEAD 16 dvlvaaeTGsGKTlafl 32
                ++l  ++ G+GKT   l
  EEA19069.1 74 HMLFYGPPGTGKTSTIL 90
                57788999*****8755 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 0.00019
                 EHHHHHHHHHCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD 104 tpgrlddllstgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqit 153
                  p+ ld    ++k  +  +++++lDEad + ++  +  ++r ++q ++it
  EEA19069.1 134 QPSGLDAAY-REKYPCPPFKIIILDEADSMTQD-AQSALRRTMEQYSRIT 181
                 555555544.4666788899***********98.9999999999998887 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   0.00014     0.094       3      30 ..      77     126 ..      76     195 .. 0.63

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 0.00014
      AAA_18   3 ltGtpGvGKttlakeLskrlgf.......................gvnlrd 30 
                   G+pG+GKt+   +L+k+l f                        ++++d
  EEA19069.1  77 FYGPPGTGKTSTILALAKSL-FgptlyrtrilelnasderginivREKIKD 126
                 57****************98.444777766666666666644444333333 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   0.00013     0.088      20     114 ..      74     176 ..      56     186 .. 0.66

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00013
      AAA_30  20 vavltGpAGtGKttalkalreaweaag...grvi.glAptgkaAkvLaeelgieastiakllkrlk....grarlepgtllivDEagmvdtkqlaallk 110
                  ++  Gp+GtGKt ++ al++ +        r++ + A+ ++  + ++e++   a+t  +  + l+    ++  + p +++i DEa  + ++   al +
  EEA19069.1  74 HMLFYGPPGTGKTSTILALAKSLFGPTlyrTRILeLNASDERGINIVREKIKDFARTQLSQPSGLDaayrEKYPCPPFKIIILDEADSMTQDAQSALRR 172
                 56788********98888866554332333222225577777777777777766666555444444777644556666999999998888777777777 PP

      AAA_30 111 aaek 114
                  +e+
  EEA19069.1 173 TMEQ 176
                 7766 PP

>> AAA_3  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00057       0.4       1      55 [.      74     128 ..      74     184 .. 0.73
   2 ?   -3.0   0.0       9.2   6.3e+03      63      90 ..     285     313 ..     265     321 .. 0.59

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00057
       AAA_3   1 hvllegvPGlaktllvkalakal.dlefkriqftpdllPsdilGtevfeekekefe 55 
                 h+l+ g PG++kt ++ alak+l + ++ r ++  +l  sd  G+++++ek k+f 
  EEA19069.1  74 HMLFYGPPGTGKTSTILALAKSLfGPTLYRTRI-LELNASDERGINIVREKIKDFA 128
                 99******************9873556667665.4788899999998888886664 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 9.2
       AAA_3  63 anllladeinrappk.tqsalleameerq 90 
                   +  ++ei    p  +   l++am+ ++
  EEA19069.1 285 ITVRTVEEIAGVVPEsVLDKLMQAMQPKK 313
                 44555555554444314456666666665 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   9.7e-05     0.067       3      21 ..      76     104 ..      74     173 .. 0.65

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 9.7e-05
      AAA_28   3 vitGgestGKTtlleaLa..........a 21 
                  + G+++tGKT+++ aLa           
  EEA19069.1  76 LFYGPPGTGKTSTILALAkslfgptlyrT 104
                 689***************43333333330 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   0.00068      0.47      14      49 ..      62      97 ..      49     107 .. 0.78
   2 ?    0.6   0.0      0.74   5.1e+02     122     155 ..     140     175 ..     104     186 .. 0.63

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00068
                HHT......TTSEEEEEESTTSTHHHHHHHHHHHH- CS
      ResIII 14 nlleklkskrdkrglikmaTGtGKTlvaaklierll 49
                 l  +l++ +  ++l+  + GtGKT ++++l+++l+
  EEA19069.1 62 VLQRTLQASNLPHMLFYGPPGTGKTSTILALAKSLF 97
                33444454677899******************9997 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.74
                 .....HHHTTT-SEEEEETGGGTTS...TTTHHHHH CS
      ResIII 122 eeeseellrdrfdviiiDEaHrlgak..kswreile 155
                   ++e++    f++ii DEa  ++++  ++ r+ +e
  EEA19069.1 140 AAYREKYPCPPFKIIILDEADSMTQDaqSALRRTME 175
                 55677777777889*****98887764324444444 PP

>> Parvo_NS1  Parvovirus non-structural protein NS1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00029       0.2      73     136 ..      27      94 ..       3     100 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00029
   Parvo_NS1  73 evt..adfdieenriykllslngynpvevgqvllawlskqlgkrnt..vwfyGpantGktnlaeaIak 136
                 ++   a+++  +++ ++  ++++++ v +  +  ++l+++l+  n    +fyGp+ tGkt    a+ak
  EEA19069.1  27 KTSenAEEKARLQPWVEKYRPKSLDDVAAQDHTTTVLQRTLQASNLphMLFYGPPGTGKTSTILALAK 94 
                 333448899999***************************9999995449***********98888776 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   0.00035      0.24      21      64 ..      74     125 ..      64     182 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00035
      AAA_23  21 ltlItGpNGaGKTTildAiklaLygetprlsrks..........grgfeksdve 64 
                   l++Gp G+GKT+ + A+   L+g t  l r++          g ++++++++
  EEA19069.1  74 HMLFYGPPGTGKTSTILALAKSLFGPT--LYRTRilelnasderGINIVREKIK 125
                 569**********************54..4444434444444433344444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (394 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       917  (0.0511462); expected 358.6 (0.02)
Passed bias filter:                      707  (0.0394333); expected 358.6 (0.02)
Passed Vit filter:                       104  (0.00580066); expected 17.9 (0.001)
Passed Fwd filter:                        27  (0.00150594); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              26  [number of targets reported over threshold]
# CPU time: 0.69u 0.31s 00:00:01.00 Elapsed: 00:00:00.48
# Mc/sec: 2466.03
//
Query:       EEA19070.1  [L=516]
Description: hypothetical protein PMAA_013340 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (516 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1523  (0.0849462); expected 358.6 (0.02)
Passed bias filter:                      613  (0.0341904); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.64u 0.28s 00:00:00.92 Elapsed: 00:00:00.44
# Mc/sec: 3533.50
//
Query:       EEA19071.1  [L=639]
Description: hypothetical protein PMAA_013350 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    0.00027   21.1   0.2         18    6.3   0.0    4.5  4  Ank_3        Ankyrin repeat
     0.0005   20.6   0.0       0.01   16.4   0.0    2.5  3  Ank_2        Ankyrin repeats (3 copies)
    0.00081   19.9   0.1        7.1    7.3   0.0    3.8  3  Ank_4        Ankyrin repeats (many copies)
     0.0021   18.3   0.0      0.035   14.4   0.0    2.6  2  Ank_5        Ankyrin repeats (many copies)
     0.0089   16.4   0.2        5.8    7.5   0.0    3.7  3  Ank          Ankyrin repeat
  ------ inclusion threshold ------
      0.076   13.3   0.2       0.17   12.2   0.2    1.5  1  Myco_19_kDa  Mycobacterium 19 kDa lipoprotein antigen


Domain annotation for each model (and alignments):
>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0      0.19   5.6e+02       1      22 [.     355     383 ..     355     390 .. 0.70
   2 !    6.3   0.0     0.006        18       4      26 ..     489     510 ..     487     512 .. 0.90
   3 ?    5.1   0.0     0.015        44       2      23 ..     520     541 ..     520     544 .. 0.91
   4 ?    1.2   0.1      0.27   8.1e+02       9      25 ..     566     586 ..     561     589 .. 0.67

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.19
       Ank_3   1 nGetpLh.lAarsgnl......eivkfLl 22 
                 +G t+Lh +Aa++ +       ++ +fLl
  EEA19071.1 355 DGFTLLHlQAALYSPGyetlftKMTDFLL 383
                 699****9999998766554433566666 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.006
       Ank_3   4 tpLhlAarsgnleivkfLlenkg 26 
                 +pLh+Aa +  ++ v++L+  +g
  EEA19071.1 489 SPLHFAAAASWPAGVRALIS-MG 510
                 8***********99****98.66 PP

  == domain 3  score: 5.1 bits;  conditional E-value: 0.015
       Ank_3   2 GetpLhlAarsgnleivkfLle 23 
                 Ge+pL +A+  g+++ v++Ll+
  EEA19071.1 520 GESPLDIAVDVGCISSVEALLK 541
                 89************88****98 PP

  == domain 4  score: 1.2 bits;  conditional E-value: 0.27
       Ank_3   9 Aarsgnl...e.ivkfLlenk 25 
                 Aa s++    + iv+ Ll+++
  EEA19071.1 566 AAASNDSrlhDiIVECLLRHN 586
                 5555555466447*****954 PP

>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0      0.23   6.9e+02      43      59 ..     336     362 ..     325     399 .. 0.58
   2 !   16.4   0.0   3.5e-06      0.01      24      76 ..     484     542 ..     459     546 .. 0.77
   3 ?   -3.6   0.0       5.9   1.8e+04      32      48 ..     566     585 ..     563     592 .. 0.53

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.23
       Ank_2  43 klLleh..........adndgrtpLhy 59 
                 klLle+          ++ dg t Lh+
  EEA19071.1 336 KLLLEKfyagdafpnaINADGFTLLHL 362
                 555553344444444444666666643 PP

  == domain 2  score: 16.4 bits;  conditional E-value: 3.5e-06
       Ank_2  24 k.ngktaLhyAakngnleivklLle..h....adndgrtpLhyAarsghleivklLlekg 76 
                 k +  ++Lh+Aa +     v++L++  +    +d  g++pL +A+  g +  v+ Ll kg
  EEA19071.1 484 KeTSISPLHFAAAASWPAGVRALISmgYsrfqVDAIGESPLDIAVDVGCISSVEALL-KG 542
                 146689*******999888*****965256678899*********99*********9.54 PP

  == domain 3  score: -3.6 bits;  conditional E-value: 5.9
       Ank_2  32 yAakngnl..ei.vklLleh 48 
                 +Aa+n+++  +i v+ Ll h
  EEA19071.1 566 AAASNDSRlhDIiVECLLRH 585
                 45555433333335666654 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   0.0     0.011        34      19      41 ..     337     362 ..     329     368 .. 0.70
   2 ?    2.6   0.0     0.071   2.1e+02      15      38 ..     377     399 ..     376     408 .. 0.92
   3 !    7.3   0.0    0.0024       7.1       3      43 ..     489     528 ..     488     540 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.011
       Ank_4  19 lLlekg....adinaqdnrsGetalhi 41 
                 lLlek     a +na  n++G+t+lh 
  EEA19071.1 337 LLLEKFyagdAFPNAI-NADGFTLLHL 362
                 45543311136699*8.*********6 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.071
       Ank_4  15 elvrlLlekgadinaqdnrsGeta 38 
                 ++ ++Ll++++d +++ +++ +ta
  EEA19071.1 377 KMTDFLLSTRVDTDMV-DKYFRTA 399
                 7899************.*999997 PP

  == domain 3  score: 7.3 bits;  conditional E-value: 0.0024
       Ank_4   3 taLhyaaisgrlelvrlLl...ekgadinaqdnrsGetalhiAa 43 
                 ++Lh aa+++    vr L+   +++ +++a     Ge++l+iA+
  EEA19071.1 489 SPLHFAAAASWPAGVRALIsmgYSRFQVDAI----GESPLDIAV 528
                 69*****************554456668777....********8 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.28   8.2e+02      30      55 ..     332     362 ..     329     362 .. 0.75
   2 !   14.4   0.0   1.2e-05     0.035       9      56 .]     480     527 ..     475     527 .. 0.88

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.28
       Ank_5  30 dvvrlLl.....argadlnltdsrGltaldl 55 
                 +v+r+Ll     a  a +n+ +++G t+l+l
  EEA19071.1 332 SVARKLLlekfyAGDAFPNAINADGFTLLHL 362
                 5666666677778888999999999998875 PP

  == domain 2  score: 14.4 bits;  conditional E-value: 1.2e-05
       Ank_5   9 vnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 +  + + + +pLh+Aa +  +  vr L+ +g ++++ d+ G+++ld+A
  EEA19071.1 480 LRSWKETSISPLHFAAAASWPAGVRALISMGYSRFQVDAIGESPLDIA 527
                 4555566669*************************************9 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.5   0.0     0.002       5.8       1      31 [.     355     393 ..     355     394 .. 0.71
   2 ?    1.2   0.0       0.2   5.9e+02       4      10 ..     489     495 ..     488     513 .. 0.68
   3 ?    2.9   0.0     0.057   1.7e+02       2      24 ..     520     542 ..     519     548 .. 0.81

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.002
                 TSBBHHHH.HH..HHTT....HHHHHHHH.TTTSTTCBT CS
         Ank   1 dGnTPLHl.Aa..tngk....kriiklLL.hGAnlnald 31 
                 dG+T LHl Aa  ++g     + ++ +LL  + + +++d
  EEA19071.1 355 DGFTLLHLqAAlySPGYetlfTKMTDFLLsTRVDTDMVD 393
                 9******84557744445555559999996688888887 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.2
                 BHHHHHH CS
         Ank   4 TPLHlAa 10 
                 +PLH Aa
  EEA19071.1 489 SPLHFAA 495
                 7***988 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.057
                 SBBHHHHHHHHTTHHHHHHHHTT CS
         Ank   2 GnTPLHlAatngkkriiklLLhG 24 
                 G +PL +A+  g  + +++LL+G
  EEA19071.1 520 GESPLDIAVDVGCISSVEALLKG 542
                 899******77866799999977 PP

>> Myco_19_kDa  Mycobacterium 19 kDa lipoprotein antigen
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.2   5.6e-05      0.17      24      87 ..     162     233 ..     152     248 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 5.6e-05
  Myco_19_kDa  24 tCtqaggaltiaig.dg.asgvsavltdgdeptvesvgigdvdGftltyaegt......gggsaevtkdgnt 87 
                  tC+++ +++ ++ + ++ a++v+av+++  + +++  + ++ +G+++ y+++       ++ s +vt++gnt
   EEA19071.1 162 TCDKQTKNMDFQRNdREgAQRVRAVVNKPGSEVMQRSSATGQGGSSMDYSSSPwpnpmkVEWSKTVTVAGNT 233
                  8************64345*********7666778888899999********997776665566777777777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (639 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       449  (0.0250432); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.56u 0.31s 00:00:00.87 Elapsed: 00:00:00.43
# Mc/sec: 4427.86
//
Query:       EEA19072.1  [L=345]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.029   14.4   7.5      0.055   13.5   7.5    1.4  1  Gly-zipper_Omp   Glycine zipper
       0.07   12.9   5.7       0.12   12.1   5.7    1.3  1  Gly-zipper_YMGG  YMGG-like Gly-zipper
       0.34   10.5   1.8       0.51   10.0   1.8    1.1  1  Srg              Srg family chemoreceptor
       0.64   10.1   7.6        1.2    9.2   7.6    1.3  1  DUF2273          Small integral membrane protein (DUF2273)
       0.65    9.7   4.4        1.1    9.0   4.4    1.3  1  Yip1             Yip1 domain


Domain annotation for each model (and alignments):
>> Gly-zipper_Omp  Glycine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   7.5   1.5e-05     0.055      15      38 ..     132     155 ..     129     156 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 1.5e-05
  Gly-zipper_Omp  15 gavggrgtGaliGAavGaavGgli 38 
                     +a++ +  Ga+iG+a+G++vGg+i
      EEA19072.1 132 TATSSSHMGAIIGGAIGGVVGGII 155
                     57777789**************98 PP

>> Gly-zipper_YMGG  YMGG-like Gly-zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   5.7   3.3e-05      0.12      26      43 ..     138     155 ..     129     156 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 3.3e-05
                      XXXXXXXXXXXXXXXXXX CS
  Gly-zipper_YMGG  26 gkGAaiGAaaGalaGgai 43 
                        GA+iG+a+G+++Gg+i
       EEA19072.1 138 HMGAIIGGAIGGVVGGII 155
                      459*************87 PP

>> Srg  Srg family chemoreceptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   1.8   0.00014      0.51     177     240 ..      61     123 ..      55     134 .. 0.73

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00014
         Srg 177 filalvltlittivtlkklkklskrlksveksLtiitiiisvvfllvavlqvllsfafflsflp 240
                 ++++  ++l+ +++++  l   ++   s   sLt +t+++s+++++va  +vl  +++ +++ +
  EEA19072.1  61 LVTTKTIMLTASVTSTIALG-SGHDQTSTAASLTTTTFVTSIGYSVVATETVLAPTNTAVHNDS 123
                 44445555555555555554.4577777789*********************988888777766 PP

>> DUF2273  Small integral membrane protein (DUF2273)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   7.6   0.00032       1.2       4      28 ..     137     161 ..     136     162 .. 0.94

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00032
     DUF2273   4 khrgkiiGaliGlilaililtiGFw 28 
                 +h g iiG++iG +++ +il++G++
  EEA19072.1 137 SHMGAIIGGAIGGVVGGIILFLGLY 161
                 699********************96 PP

>> Yip1  Yip1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   4.4    0.0003       1.1      32      86 ..      95     162 ..      66     171 .. 0.75

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.0003
        Yip1  32 ltlllgllaslnlgqtlasg.............eevqgltlssllgaiiggylglllgllllalllhl 86 
                 +t++ ++ +s +++ t+ ++             + v++ t+ss++gaiigg++g+++g ++l l l+l
  EEA19072.1  95 TTFVTSIGYSVVATETVLAPtntavhndssnvvDGVPTATSSSHMGAIIGGAIGGVVGGIILFLGLYL 162
                 4455555555333333333355666667777788899999******************9999999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (345 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       663  (0.0369792); expected 358.6 (0.02)
Passed bias filter:                      379  (0.0211389); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.71u 0.32s 00:00:01.03 Elapsed: 00:00:00.59
# Mc/sec: 1768.05
//
Query:       EEA19073.1  [L=647]
Description: succinate dehydrogenase subunit Sdh1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   4.8e-126  421.2   3.5   6.2e-126  420.8   3.5    1.1  1  FAD_binding_2   FAD binding domain
    1.6e-44  151.0   1.3    2.4e-44  150.4   1.3    1.3  1  Succ_DH_flav_C  Fumarate reductase flavoprotein C-term
    2.4e-06   27.0   0.2    0.00091   18.5   0.1    3.0  3  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    2.8e-05   23.4   1.1      0.024   13.7   1.9    2.3  2  GIDA            Glucose inhibited division protein A
    0.00025   20.3   0.2      0.049   12.9   0.1    2.3  2  Thi4            Thi4 family
     0.0037   16.6   0.2     0.0075   15.6   0.2    1.5  1  FAD_binding_3   FAD binding domain
     0.0065   16.1   0.9       0.02   14.5   0.9    1.9  1  DAO             FAD dependent oxidoreductase
  ------ inclusion threshold ------
       0.21   10.3   1.5       0.93    8.1   0.8    2.3  3  HI0933_like     HI0933-like protein
        2.6    7.2   3.8        4.3    6.5   0.8    2.6  3  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase


Domain annotation for each model (and alignments):
>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  420.8   3.5  3.1e-129  6.2e-126       1     417 []      62     457 ..      62     457 .. 0.99

  Alignments for each domain:
  == domain 1  score: 420.8 bits;  conditional E-value: 3.1e-129
                    SEEEE--SHHHHHHHHHHHHTTT-EEEEESSSGGGSGGGG--S-EE-TT..SSGGSTC.CHHHHHHHHHHHHTTT-S-HHHHHHHHHTHHHHHHHH CS
  FAD_binding_2   1 DviViGsGlAGLaAAleaaeaGlkvavvekeqefggatawsqGgidavlspeqkkagikdspelhrtdtlkaldeladqplveafveaapeavdeL 96 
                    D++V+G+G+AGL+AA  +aeaG ++a+v+k ++++++t+++qGgi+a+l +++     kd++++h++dt+k++d+l+dq+++++++++ap+ v+eL
     EEA19073.1  62 DAVVVGAGGAGLRAAFGLAEAGFNTACVSKLFPTRSHTVAAQGGINAAL-GNM----HKDDWRWHMYDTVKGSDWLGDQDAIHYMTREAPASVREL 152
                    89***********************************************.777....4799*********************************** PP

                    HHTT----BCCTSSB-EEE-TT-SST.......EEEE-.STT-......HHHHHHHHHHHHHHTCTEEEEESEEEEEEEECTTEEEEEEEEETTTT CS
  FAD_binding_2  97 eelgvpfsrtedgpvdvrelGglsat.......artlhdaadarretlvtghallarlvesarkagvdfqerteadeLivedgrvtGavvenpesg 185
                    e +g+pfsrtedg +++r +Gg+s++        r+++ aad+      tghall++l+ + +++++ ++ +++a++L++edg+++G+++ n+e+g
     EEA19073.1 153 EGYGCPFSRTEDGLIYQRAFGGQSQDfgkggqaYRCCA-AADR------TGHALLHTLYGQSLRHNTNYFIEYFALDLLMEDGECRGIIAYNQEDG 241
                    ********************************999999.****......*********************************************** PP

                    CEEEEEESEEEE-----GG..........GSSSBSSGTT-S-HHHHHHHCTTSSEES..TT-EEEEEEEET....TTTBB--THHHHTT-EEE-TT CS
  FAD_binding_2 186 revrirakavvlatgGfgrallkellgaaaeaettnapavtGdglalalragaalnddrmeevqfhPtslvpirdgsgiLitealrgeGgilvdkd 281
                    + +r++a+++vlatgG+gr          a++++t+a+++tGdg a+++rag++ +d  +e+vqfhPt+++    g+g+Lite+ rgeGgil++++
     EEA19073.1 242 TLHRFKAHHTVLATGGYGR----------AYFSCTSAHTCTGDGMAMVARAGLPNQD--LEFVQFHPTGIY----GAGCLITEGSRGEGGILLNSE 321
                    *******************..........*************************999..************....********************* PP

                    SSBTH.......GGGS-HHHHHHHHH.HHHHTTTS....CCBEEEE-TT.SSHHHHHHHSHHHHHHHHHCCT......S-TTTSEEE.......EE CS
  FAD_binding_2 282 GrrFm.......nelasrdvvsrailekeiaeggs....eanvyldashgldaegleatleaineeaangldkdfgrgidpadrpipgpfyavkvv 366
                    G+rFm       ++lasrdvvsr+++  ei+eg++    ++++yl +sh l+ae l+++l++i e+a  +++      +d +++pip       v 
     EEA19073.1 322 GERFMeryaptaKDLASRDVVSRSMT-LEIREGRGvgpeKDHIYLQLSH-LPAELLHERLPGISETASIFAG------VDVTKEPIP-------VL 402
                    **************************.**********************.**********************......*********.......** PP

                    EEEEEES-EEEBETTSBE....STTEEESSBTEEE-STCEESSSSTTS--TTHHH CS
  FAD_binding_2 367 paqhytmgGvetdengrv....ldadgqpipGLYAaGevaaggvhganrlgGnsl 417
                    p++hy+mgG++t ++g+v     + +++++pGLYA+Ge+a+++vhganrlg+nsl
     EEA19073.1 403 PTVHYNMGGIPTRYTGEVvtldENGNDKTVPGLYACGEAACVSVHGANRLGANSL 457
                    ********************88888899*************************98 PP

>> Succ_DH_flav_C  Fumarate reductase flavoprotein C-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  150.4   1.3   1.2e-47   2.4e-44       1     128 []     512     647 .]     512     647 .] 0.97

  Alignments for each domain:
  == domain 1  score: 150.4 bits;  conditional E-value: 1.2e-47
                     .HHHHHHHHHHSSSSB-HHHHHHHHHHHHHHHHHHTTB--S---SSS-HHHHHHHHHHHHHHHHHHHHHHHHH--S-BTTBEBTTS-SEETTT-S CS
  Succ_DH_flav_C   1 rkeLgkimqkkvgvfRteegLkealkelkelrerlknvkvtdkskvaNqelvealelanllelAeaiaksAlaRkESrGaHaredfperdDenwl 95 
                     r++++k+mq++v+vfRt+e+L+e+++++ ++ + +++v+++d+s+++N++lve+lel+nll++A+++a++A +RkESrGaHared+p+rdDenw+
      EEA19073.1 512 RNAMQKTMQTDVSVFRTQESLDEGVAKITQVDAMFDQVGTKDRSMIWNSDLVETLELRNLLTCATQTAHAAANRKESRGAHAREDYPDRDDENWM 606
                     789******************************************************************************************** PP

                     EEEEE...TT-SS-EEEEEE--GGG-........-S---SS CS
  Succ_DH_flav_C  96 khtlasldaakeeveleyepveletl........kpkeRsY 128
                     khtl+++++ +++v+l+y+ v+ +tl        +p +R+Y
      EEA19073.1 607 KHTLTYQKNPHGKVDLTYRAVQAHTLdekeckpvPPFKRVY 647
                     ***********************999999888888888888 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.1   4.6e-07   0.00091       1      31 [.      61      95 ..      61     156 .. 0.86
   2 ?    0.2   0.0      0.18   3.6e+02      89     111 ..     237     259 ..     172     289 .. 0.84
   3 ?    4.2   0.0     0.011        21     248     278 ..     410     442 ..     400     456 .. 0.75

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 4.6e-07
                 CSEEEE--SHHHHHHHHHHHHHTS-EEEEE....T CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....x RF
  Pyr_redox_2  1 kdvvviGgGpAGlaaaltlaqagakvtlve....l 31
                 +d vv+G+G AGl+aa  la+ag+++++v+     
   EEA19073.1 61 YDAVVVGAGGAGLRAAFGLAEAGFNTACVSklfpT 95
                 588**************************555443 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.18
                  EEECTCEEEEEESEEEE---EEE CS
                  xxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  89 kkkegdeekiaydklvlAtGssp 111
                  ++++g  +++++++ vlAtG+  
   EEA19073.1 237 NQEDGTLHRFKAHHTVLATGGYG 259
                  4556889999**********844 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.011
                  CT-EEEETTEE.E--TTSBES.STTEEE-GGGC CS
                  xxxxxxxxxxx.xxxxxxxxx.xxxxxxxxxxx RF
  Pyr_redox_2 248 lglelderggi.vvdeflrtn.vpgiyaiGDva 278
                   g+++  +g +   de+++ + vpg+ya+G  a
   EEA19073.1 410 GGIPTRYTGEVvTLDENGNDKtVPGLYACGEAA 442
                  5677766777746799997655********988 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.7   1.9   1.2e-05     0.024       1      29 [.      62      94 ..      62     116 .. 0.77
   2 !    6.5   0.0    0.0019       3.9     114     172 ..     216     280 ..     177     309 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.2e-05
                CEEEE-SSHHHHHHHHHHHHTT--EEEE....E CS
        GIDA  1 dviViGgGhAGceAAlaaarlGakvlLi....t 29
                d +V+G+G AG+ AA+ +a++G++++ +     
  EEA19073.1 62 DAVVVGAGGAGLRAAFGLAEAGFNTACVsklfP 94
                579**********************98844442 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0019
                 EES-EEEEEECTTEEEEEEETTS-.....EEEECEEEE--TT-BT-EEEETTEEEESSC.TTC-- CS
        GIDA 114 ieeeveeliveekkvkgvvtedge.....tikakavviatGtflkgkihigekelsaGr.lgelt 172
                 ie  + +l++e+++++g++  ++e      +ka+++v+atG + ++   + + ++ +G  ++  +
  EEA19073.1 216 IEYFALDLLMEDGECRGIIAYNQEdgtlhRFKAHHTVLATGGYGRAYFSCTSAHTCTGDgMAMVA 280
                 4555667779999999988766542223368888***********99999888877776555444 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.9   0.1   2.5e-05     0.049      17      47 ..      60      89 ..      53     107 .. 0.88
   2 !    5.2   0.0    0.0056        11     208     233 ..     428     454 ..     417     455 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.5e-05
                EEEEEEE--SHHHHHHHHHHHHCTTS-EEEE CS
        Thi4 17 esDvvivGaGssGLtaayylakkpdlkvail 47
                e D v+vGaG +GL aa+ la++ ++++a +
  EEA19073.1 60 EYDAVVVGAGGAGLRAAFGLAEA-GFNTACV 89
                789******************99.8887765 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0056
                 ECEEETTEEE-THHH.HHHHT-EB--S CS
        Thi4 208 trevvpnlyvaGmev.aevdganRmGp 233
                   + vp+ly++G ++   v+ganR+G+
  EEA19073.1 428 NDKTVPGLYACGEAAcVSVHGANRLGA 454
                 5689********8652689******97 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.2   3.7e-06    0.0075       2      37 ..      61      96 ..      60     108 .. 0.85

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 3.7e-06
                   EEEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSC CS
  FAD_binding_3  2 tdVlIVGaGpaGlmlallLseaGvrvvlvekrsttv 37
                   +d ++VGaG aGl +a  L+eaG ++ +v k   t 
     EEA19073.1 61 YDAVVVGAGGAGLRAAFGLAEAGFNTACVSKLFPTR 96
                   7899*************************9986554 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.9     1e-05      0.02       1      84 [.      62     162 ..      62     266 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 1e-05
                 EEEEECTSHHHHHHHHHHHHTT..EEEEESSSSTTSSGGGSSEEEEESSS.....STHHSTH...................HHHHHHHHHHHHHHHHHH CS
         DAO   1 dvviiGGGiiGlstAyeLarrg..VtllekgdiagsgaSgrnsgllhsgl.....rylpeas...................elarlslealeelrelee 73 
                 d v++G+G +Gl +A+ La++g  ++ + k  ++ +  + +++g + ++l     +                         +++ +++ea +  rele+
  EEA19073.1  62 DAVVVGAGGAGLRAAFGLAEAGfnTACVSKL-FPTRSHTVAAQGGINAALgnmhkD-----DwrwhmydtvkgsdwlgdqdAIHYMTREAPASVRELEG 154
                 78*********************99999999.888899999999999977433221.....25556677777778888888888888888888888886 PP

                 HHSSTTSEEEE CS
         DAO  74 elgididyrrt 84 
                  +g  +++ rt
  EEA19073.1 155 -YG--CPFSRT 162
                 .57..555553 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.8   0.00047      0.93       2      29 ..      62      89 ..      61     116 .. 0.84
   2 ?   -2.9   0.0       1.1   2.1e+03     151     165 ..     244     258 ..     237     266 .. 0.85
   3 ?   -0.9   0.0      0.26   5.2e+02     373     384 ..     430     441 ..     417     449 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00047
                 SEEEE--SHHHHHHHHHHHHTT--EEEE CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVlll 29
                 d +v+G+G AGl aA  +a++g +++ +
   EEA19073.1 62 DAVVVGAGGAGLRAAFGLAEAGFNTACV 89
                 89*****************999887665 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.1
                  EEEEESEEEE----S CS
  HI0933_like 151 eeleadklvlAtGGl 165
                  ++++a+++vlAtGG 
   EEA19073.1 244 HRFKAHHTVLATGGY 258
                  578999*******96 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 0.26
                  TTSTTEEE-GGG CS
  HI0933_like 373 kkvpgLffaGEv 384
                  k+vpgL+ +GE 
   EEA19073.1 430 KTVPGLYACGEA 441
                  89*********4 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.8    0.0022       4.3       1      24 [.      64      87 ..      64      91 .. 0.89
   2 ?   -0.3   0.0      0.26   5.2e+02     122     139 ..     245     262 ..     240     270 .. 0.85
   3 ?   -1.8   0.0      0.73   1.4e+03     286     305 .]     420     439 ..     411     439 .. 0.86

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0022
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledy 24
                 +++GaG aGl aa  l +ag+++ 
   EEA19073.1 64 VVVGAGGAGLRAAFGLAEAGFNTA 87
                 79******************9765 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.26
  Pyr_redox_3 122 tyeAkkviiAtGefdkPn 139
                   ++A++ ++AtG +++ +
   EEA19073.1 245 RFKAHHTVLATGGYGRAY 262
                  689***********9876 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 0.73
  Pyr_redox_3 286 rpvlteeteetnvpglflaG 305
                   ++l+e+ ++ +vpgl+ +G
   EEA19073.1 420 VVTLDENGNDKTVPGLYACG 439
                  67899999*********999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (647 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       459  (0.025601); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.80u 0.36s 00:00:01.16 Elapsed: 00:00:00.57
# Mc/sec: 3447.05
//
Query:       EEA19074.1  [L=439]
Description: proteasome regulatory particle subunit Rpt1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.9e-41  140.0   0.0    1.1e-40  139.2   0.0    1.4  1  AAA           ATPase family associated with various cellular 
    7.8e-06   25.6   0.1      2e-05   24.3   0.1    1.7  1  AAA_lid_3     AAA+ lid domain
      7e-05   23.1   0.0     0.0059   16.9   0.0    2.4  2  AAA_22        AAA domain
    0.00011   22.2   0.0    0.00043   20.3   0.0    2.2  1  AAA_5         AAA domain (dynein-related subfamily)
    0.00023   21.3   0.0    0.00069   19.8   0.0    1.7  1  AAA_2         AAA domain (Cdc48 subfamily)
    0.00032   21.1   0.1      0.008   16.6   0.0    2.4  2  AAA_16        AAA ATPase domain
     0.0019   17.4   0.0     0.0035   16.6   0.0    1.4  1  DUF815        Protein of unknown function (DUF815)
     0.0082   15.9   0.0      0.016   15.0   0.0    1.4  1  RuvB_N        Holliday junction DNA helicase RuvB P-loop doma
  ------ inclusion threshold ------
       0.02   15.1   0.1      0.063   13.5   0.0    1.8  2  AAA_28        AAA domain
      0.029   13.9   0.0      0.097   12.2   0.0    1.9  1  AAA_7         P-loop containing dynein motor region
      0.049   13.8   0.0      0.094   12.9   0.0    1.5  1  AAA_33        AAA domain
      0.058   13.8   0.0       0.16   12.4   0.0    1.8  1  RNA_helicase  RNA helicase
      0.082   12.6   0.1       0.59    9.8   0.0    2.2  2  AAA_30        AAA domain
      0.084   12.7   0.0       0.16   11.9   0.0    1.5  1  AAA_3         ATPase family associated with various cellular 
      0.096   13.0   0.1       0.22   11.8   0.1    1.6  1  DUF4164       Domain of unknown function (DUF4164)
      0.097   12.4   0.0       0.24   11.1   0.0    1.8  1  AAA_24        AAA domain
       0.14   12.7   0.0       0.48   11.0   0.0    2.0  2  AAA_18        AAA domain
       0.14   12.2   0.0       0.33   11.0   0.0    1.6  1  AAA_14        AAA domain
       0.16   11.3   0.0       0.36   10.2   0.0    1.5  1  Mg_chelatase  Magnesium chelatase, subunit ChlI


Domain annotation for each model (and alignments):
>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.2   0.0   1.1e-43   1.1e-40       2     131 ..     219     350 ..     218     351 .. 0.95

  Alignments for each domain:
  == domain 1  score: 139.2 bits;  conditional E-value: 1.1e-43
                 EEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHH...TTCCCHHHHHHHHHHHHHHHHTT CS
         AAA   2 llyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksr...sgseseeeervvnqLlteldgvk 97 
                 llyGppGtGKTl+a+ava+ ++++f+++ gsel++kyvge+++ +relf+ a++k+  +i+f+DEida++++r     + ++e +r++ +L+t+ldg++
  EEA19074.1 219 LLYGPPGTGKTLCARAVANRTDATFIRVIGSELVQKYVGEGARMVRELFEMARTKK-ACIIFFDEIDAIGGARfddGAGGDNEVQRTMLELITQLDGFD 316
                 9*****************************************************98.9***************996566889999************** PP

                 TSSSTEEEEEEESSGGGSTHHHHS.TTSSEEEETT CS
         AAA  98 kkeskvivigatnrpdkldpallr.gRfdrkieie 131
                 ++ +++ v+ atnrp++ldpal+r gR+drkie++
  EEA19074.1 317 SR-GNIKVMFATNRPSTLDPALMRpGRIDRKIEFS 350
                 *7.66***************************997 PP

>> AAA_lid_3  AAA+ lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.3   0.1   2.1e-08     2e-05       4      44 ..     376     416 ..     373     417 .. 0.90

  Alignments for each domain:
  == domain 1  score: 24.3 bits;  conditional E-value: 2.1e-08
   AAA_lid_3   4 lkeLAerTeGySGADlaalcreAallAlrrgikeitmedfe 44 
                 ++ + +++++ +GA+l ++  eA++ A+r  +k  t++df 
  EEA19074.1 376 WELISRLCPNATGAELRSVATEAGMFAIRARRKVATEKDFL 416
                 566889*********************************95 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.0   6.3e-06    0.0059       8      30 ..     218     240 ..     213     252 .. 0.85
   2 ?    4.3   0.0     0.049        46      57     127 ..     244     325 ..     239     329 .. 0.71

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 6.3e-06
      AAA_22   8 lvvtGesGtGKTtllrrlleqld 30 
                  +++G++GtGKT+++r ++++ d
  EEA19074.1 218 ALLYGPPGTGKTLCARAVANRTD 240
                 589****************9984 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.049
      AAA_22  57 lrellralglelkaerlsseellealeqalraravielliiDEaqhlr....s..........eealeeLrsllnl.srkgvqliL 127
                  r + ++l ++  +   +  ++++ l + +r++++  ++  DE++ +                 ++le + +l  + sr ++++ +
  EEA19074.1 244 IRVIGSELVQKYVG---EGARMVRELFEMARTKKA-CIIFFDEIDAIGgarfDdgaggdnevqRTMLELITQLDGFdSRGNIKVMF 325
                 55555555555555...667777777777888888.9**********776551556667778788888887777767888888876 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0   4.5e-07   0.00043       3      77 ..     219     286 ..     217     339 .. 0.83

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 4.5e-07
                 EEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--.........--------..G-SEEEEESGGG- CS
       AAA_5   3 lLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreikngttslvdsplvraar..egeilvlDEvera 77 
                 lL GppGtgK+  a+ +a ++ +++  v +++      l++++   +g +     +l + ar  +++i+++DE++ +
  EEA19074.1 219 LLYGPPGTGKTLCARAVANRTDATFIRVIGSE------LVQKYVG-EGARMV--RELFEMARtkKACIIFFDEIDAI 286
                 8*********************9999999876......8888883.333333..44444444459*********976 PP

>> AAA_2  AAA domain (Cdc48 subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.0   7.3e-07   0.00069       7     104 ..     219     310 ..     214     326 .. 0.74

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 7.3e-07
                 EEE--TTSSHHHHHHHHHHHTT-....-EEEEEGGG---..----THHHHHHHHHTTT-HHHHTTSEEEEETGGG-------------HHHHHHHHHHH CS
       AAA_2   7 lllgptgvGktelakalaellfvkkekkliradaselle..eeevehlvsrligappgyvgaeegGivllDEidKihpkessgadvSregVqrdLLqil 103
                 ll gp g+Gkt+ a+a+a+  ++    ++ir+  sel +    e +++v +l      + + ++  i+++DEid i   +        ++Vqr +L ++
  EEA19074.1 219 LLYGPPGTGKTLCARAVANRTDA----TFIRVIGSELVQkyVGEGARMVREL----FEMARTKKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELI 309
                 788******************96....9***999999992222333333333....3455666778**********99633444445579******998 PP

                 H CS
       AAA_2 104 e 104
                  
  EEA19074.1 310 T 310
                 5 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   8.4e-06     0.008       7      50 ..     188     241 ..     185     256 .. 0.70
   2 ?    1.5   0.0      0.38   3.5e+02     124     146 ..     264     290 ..     258     314 .. 0.75

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 8.4e-06
      AAA_16   7 eeleqLlsale.rvrsgrp.........elvllsGesGvGKsslvrellralek 50 
                 e++e+L++++e ++ s++             ll+G++G+GK+  +r+++++  +
  EEA19074.1 188 EQIEKLREVVEmPLLSPERfvnlgidppKGALLYGPPGTGKTLCARAVANRTDA 241
                 5666666666644444444555555666899*****************975444 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.38
      AAA_16 124 krllallsrderplvlvlDdlq.....w 146
                 ++l++ +++ ++  ++++D+++     +
  EEA19074.1 264 RELFEMART-KKACIIFFDEIDaiggaR 290
                 556677777.777********9555554 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   3.7e-06    0.0035      52     116 ..     214     283 ..     167     287 .. 0.83

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 3.7e-06
      DUF815  52 pannvLLwGarGtGKSslvkallneyaeegLrli..evekedlkelpklvellr...erperfilfvDDL 116
                 p + +LL+G  GtGK  + +a+ n++ ++ +r+i  e+ ++ + e  ++v++l    ++++ +i+f D +
  EEA19074.1 214 PPKGALLYGPPGTGKTLCARAVANRTDATFIRVIgsELVQKYVGEGARMVRELFemaRTKKACIIFFDEI 283
                 56789*****************************88888999999888888765232678899***9975 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   1.7e-05     0.016      36      94 ..     218     284 ..     212     289 .. 0.66

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.7e-05
      RuvB_N  36 vllyGpPGlGkttlakiiakelgvkl.kitsgPvleka.gdlaalltnl......eekdvlfideih 94 
                  llyGpPG Gkt  a+ +a+  ++++ ++  +  ++k  g+ a ++ +l      ++  ++f dei 
  EEA19074.1 218 ALLYGPPGTGKTLCARAVANRTDATFiRVIGSELVQKYvGEGARMVRELfemartKKACIIFFDEID 284
                 69*******************9988515555555555325555554444222222344577888775 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       4.2     4e+03      53      90 ..      45      84 ..      28     110 .. 0.64
   2 ?   13.5   0.0   6.7e-05     0.063       4      40 ..     220     261 ..     218     281 .. 0.74

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 4.2
      AAA_28 53 lafaervleeqleeeaaa..aankvlfcDrglldtlaYar 90
                 a a + le+q++e ++   ++ +v  +D+gl  +  +  
  EEA19074.1 45 YAAALKKLEKQIKEKQQSvnEKIGVKESDTGLAPPHLWDV 84
                4555566677776666555566667777777776666654 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 6.7e-05
      AAA_28   4 itGgestGKTtlleaLaar....gypvv.pEaareileekla 40 
                 + G+++tGKT  ++a a+r     ++v+  E + +++ e+++
  EEA19074.1 220 LYGPPGTGKTLCARAVANRtdatFIRVIgSELVQKYVGEGAR 261
                 78***************8876556777777777777766553 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0    0.0001     0.097      27      69 ..     209     243 ..     201     287 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.0001
       AAA_7  27 elllknkkpvllvGptGtGKtviikdllkkldkekylsltinf 69 
                 +l ++  k  ll+Gp GtGKt++++ + ++ d         +f
  EEA19074.1 209 NLGIDPPKGALLYGPPGTGKTLCARAVANRTD--------ATF 243
                 5566667889****************999998........233 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0    0.0001     0.094       3      39 ..     219     257 ..     218     280 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 0.0001
      AAA_33   3 llvGlpGsGKstlaerllkklg..avllssdtlrrrlfg 39 
                 ll G+pG+GK+  a+ ++++++  ++++   +l ++++g
  EEA19074.1 219 LLYGPPGTGKTLCARAVANRTDatFIRVIGSELVQKYVG 257
                 578***************999966666666666666655 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   0.00017      0.16       2      62 ..     219     270 ..     218     287 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00017
  RNA_helicase   2 wlyGpsgeGKStlakeLakallkklklkkkdsvysrnpeddfwdgYtgqevvvidDfgqvk 62 
                   +lyGp+g+GK+++a+ +          +++d +++r   ++ +++Y g+ + ++ ++ ++ 
    EEA19074.1 219 LLYGPPGTGKTLCARAV---------ANRTDATFIRVIGSELVQKYVGEGARMVRELFEMA 270
                   69**************3.........45567777788888888888877777777766655 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0       0.7   6.6e+02      48      77 ..      38      67 ..      27     108 .. 0.77
   2 ?    9.8   0.0   0.00062      0.59      21      51 ..     218     248 ..     212     279 .. 0.89

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.7
      AAA_30 48 rviglAptgkaAkvLaeelgieastiakll 77
                +  g+Ap ++a k+L++++  + +++++ +
  EEA19074.1 38 KTYGAAPYAAALKKLEKQIKEKQQSVNEKI 67
                567999999999999998887776666555 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00062
      AAA_30  21 avltGpAGtGKttalkalreaweaaggrvig 51 
                 a+l Gp+GtGKt   +a+++  +a   rvig
  EEA19074.1 218 ALLYGPPGTGKTLCARAVANRTDATFIRVIG 248
                 5789**************9988887777776 PP

>> AAA_3  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   0.00017      0.16       3      30 ..     219     246 ..     217     279 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00017
       AAA_3   3 llegvPGlaktllvkalakaldlefkri 30 
                 ll g PG++ktl ++a+a+  d++f r+
  EEA19074.1 219 LLYGPPGTGKTLCARAVANRTDATFIRV 246
                 8999*********************998 PP

>> DUF4164  Domain of unknown function (DUF4164)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.1   0.00023      0.22       6      65 ..      45     105 ..      41     111 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00023
     DUF4164   6 leaaltrLeaaldsLEkavdrrleaerkrdele.aeiealgedrsRLaeeLdqaearaarl 65 
                  +aal++Le+ +++  ++v++++  +++   l+   +  +++dr+R+aee   + ar++++
  EEA19074.1  45 YAAALKKLEKQIKEKQQSVNEKIGVKESDTGLApPHLWDVAADRQRMAEEQPLQVARCTKI 105
                 5789999999999999999999998887766651678*************98888888875 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00026      0.24       5      22 ..     218     235 ..     215     321 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00026
      AAA_24   5 iliyGpsgiGKTtlakel 22 
                  l+yGp+g+GKT +a+  
  EEA19074.1 218 ALLYGPPGTGKTLCARAV 235
                 589**********99987 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00051      0.48       2      25 ..     219     249 ..     219     320 .. 0.79
   2 ?   -2.5   0.0       7.3   6.9e+03      19      49 ..     380     412 ..     377     432 .. 0.56

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00051
      AAA_18   2 lltGtpGvGKttlakeLskrl.gf......g 25 
                 ll G+pG+GKt  a+++++r+ +       +
  EEA19074.1 219 LLYGPPGTGKTLCARAVANRTdATfirvigS 249
                 589**************99984335655542 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 7.3
      AAA_18  19 skrlgf..gvnlrdvakenglllevdpealdes 49 
                 s+++ +  g +lr+va+e g+   +   ++  +
  EEA19074.1 380 SRLCPNatGAELRSVATEAGMFAIRARRKVATE 412
                 555533478888888888887555444444444 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00035      0.33       6      76 ..     219     286 ..     215     325 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00035
      AAA_14   6 vitGaRrvGKTtllkqlikellvkkesilyinldderdkkladpekllelileklkeekktylflDEiqev 76 
                 ++ G+  +GKT  ++ ++++       ++ +   +  +k   + +++ ++++e+++++k  ++f+DEi  +
  EEA19074.1 219 LLYGPPGTGKTLCARAVANRTD---ATFIRVIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAI 286
                 789999*******999996666...5555554444444444444467778888765668888******987 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   0.00038      0.36      26      42 ..     219     235 ..     211     242 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00038
  Mg_chelatase  26 llvGppGsGKtmlakrl 42 
                   ll+GppG+GKt+ a+++
    EEA19074.1 219 LLYGPPGTGKTLCARAV 235
                   89************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (439 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       662  (0.0369234); expected 358.6 (0.02)
Passed bias filter:                      516  (0.0287802); expected 358.6 (0.02)
Passed Vit filter:                        85  (0.00474092); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              19  [number of targets reported over threshold]
# CPU time: 0.70u 0.37s 00:00:01.06 Elapsed: 00:00:00.55
# Mc/sec: 2395.94
//
Query:       EEA19075.1  [L=349]
Description: proteasome regulatory particle subunit Rpt1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.1e-41  140.5   0.0    6.6e-41  139.8   0.0    1.3  1  AAA           ATPase family associated with various cellular 
    6.7e-06   25.8   0.1    1.5e-05   24.7   0.1    1.6  1  AAA_lid_3     AAA+ lid domain
      4e-05   23.9   0.0     0.0044   17.3   0.0    2.4  2  AAA_22        AAA domain
    6.6e-05   22.9   0.1    0.00029   20.9   0.0    2.2  2  AAA_5         AAA domain (dynein-related subfamily)
    0.00021   21.4   0.0    0.00046   20.4   0.0    1.5  1  AAA_2         AAA domain (Cdc48 subfamily)
    0.00023   21.6   0.1      0.005   17.2   0.0    2.2  2  AAA_16        AAA ATPase domain
     0.0013   17.9   0.0     0.0023   17.1   0.0    1.4  1  DUF815        Protein of unknown function (DUF815)
     0.0057   16.4   0.0      0.011   15.5   0.0    1.4  1  RuvB_N        Holliday junction DNA helicase RuvB P-loop doma
  ------ inclusion threshold ------
      0.019   14.5   0.0      0.063   12.8   0.0    1.9  1  AAA_7         P-loop containing dynein motor region
      0.026   14.8   0.0      0.044   14.0   0.0    1.3  1  AAA_28        AAA domain
      0.039   14.1   0.0      0.068   13.3   0.0    1.4  1  AAA_33        AAA domain
      0.051   14.0   0.0       0.11   12.9   0.0    1.6  1  RNA_helicase  RNA helicase
      0.062   13.2   0.0       0.11   12.3   0.0    1.5  1  AAA_3         ATPase family associated with various cellular 
      0.072   12.8   0.1       0.21   11.3   0.0    1.9  2  AAA_24        AAA domain
      0.099   13.2   0.0       0.34   11.5   0.0    1.9  2  AAA_18        AAA domain
       0.12   12.3   0.0        7.6    6.4   0.0    2.3  2  ATPase_2      ATPase domain predominantly from Archaea
       0.12   12.4   0.0       0.22   11.5   0.0    1.4  1  AAA_14        AAA domain
       0.14   11.6   0.0       0.27   10.6   0.0    1.4  1  Mg_chelatase  Magnesium chelatase, subunit ChlI


Domain annotation for each model (and alignments):
>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.8   0.0   6.6e-44   6.6e-41       2     131 ..     129     260 ..     128     261 .. 0.95

  Alignments for each domain:
  == domain 1  score: 139.8 bits;  conditional E-value: 6.6e-44
                 EEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHH...TTCCCHHHHHHHHHHHHHHHHTT CS
         AAA   2 llyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksr...sgseseeeervvnqLlteldgvk 97 
                 llyGppGtGKTl+a+ava+ ++++f+++ gsel++kyvge+++ +relf+ a++k+  +i+f+DEida++++r     + ++e +r++ +L+t+ldg++
  EEA19075.1 129 LLYGPPGTGKTLCARAVANRTDATFIRVIGSELVQKYVGEGARMVRELFEMARTKK-ACIIFFDEIDAIGGARfddGAGGDNEVQRTMLELITQLDGFD 226
                 9*****************************************************98.9***************996566889999************** PP

                 TSSSTEEEEEEESSGGGSTHHHHS.TTSSEEEETT CS
         AAA  98 kkeskvivigatnrpdkldpallr.gRfdrkieie 131
                 ++ +++ v+ atnrp++ldpal+r gR+drkie++
  EEA19075.1 227 SR-GNIKVMFATNRPSTLDPALMRpGRIDRKIEFS 260
                 *7.66***************************997 PP

>> AAA_lid_3  AAA+ lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.1   1.5e-08   1.5e-05       4      44 ..     286     326 ..     283     327 .. 0.90

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 1.5e-08
   AAA_lid_3   4 lkeLAerTeGySGADlaalcreAallAlrrgikeitmedfe 44 
                 ++ + +++++ +GA+l ++  eA++ A+r  +k  t++df 
  EEA19075.1 286 WELISRLCPNATGAELRSVATEAGMFAIRARRKVATEKDFL 326
                 566889*********************************95 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0   4.5e-06    0.0044       8      30 ..     128     150 ..     123     162 .. 0.85
   2 ?    4.8   0.0     0.032        31      57     127 ..     154     235 ..     149     239 .. 0.71

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 4.5e-06
      AAA_22   8 lvvtGesGtGKTtllrrlleqld 30 
                  +++G++GtGKT+++r ++++ d
  EEA19075.1 128 ALLYGPPGTGKTLCARAVANRTD 150
                 589****************9984 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.032
      AAA_22  57 lrellralglelkaerlsseellealeqalraravielliiDEaqhlr....s..........eealeeLrsllnl.srkgvqliL 127
                  r + ++l ++  +   +  ++++ l + +r++++  ++  DE++ +                 ++le + +l  + sr ++++ +
  EEA19075.1 154 IRVIGSELVQKYVG---EGARMVRELFEMARTKKA-CIIFFDEIDAIGgarfDdgaggdnevqRTMLELITQLDGFdSRGNIKVMF 235
                 55555555555555...667777777777888888.9**********776551556667778788888887777767888888876 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0         8   7.9e+03      28      48 ..      37      57 ..      33      64 .. 0.78
   2 !   20.9   0.0   2.9e-07   0.00029       3      77 ..     129     196 ..     127     249 .. 0.83

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 8
                EEEE--TT--HHHHH--B--. CS
       AAA_5 28 eyvqltrdtteedlkgrreik 48
                ++v+l ++ +++d+  ++++ 
  EEA19075.1 37 FVVNLGERVSPTDIEEGMRVG 57
                788899999999999999986 PP

  == domain 2  score: 20.9 bits;  conditional E-value: 2.9e-07
                 EEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--.........--------..G-SEEEEESGGG- CS
       AAA_5   3 lLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreikngttslvdsplvraar..egeilvlDEvera 77 
                 lL GppGtgK+  a+ +a ++ +++  v +++      l++++   +g +     +l + ar  +++i+++DE++ +
  EEA19075.1 129 LLYGPPGTGKTLCARAVANRTDATFIRVIGSE------LVQKYVG-EGARMV--RELFEMARtkKACIIFFDEIDAI 196
                 8*********************9999999876......8888883.333333..44444444459*********976 PP

>> AAA_2  AAA domain (Cdc48 subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.0   4.6e-07   0.00046       7     104 ..     129     220 ..     124     236 .. 0.74

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 4.6e-07
                 EEE--TTSSHHHHHHHHHHHTT-....-EEEEEGGG---..----THHHHHHHHHTTT-HHHHTTSEEEEETGGG-------------HHHHHHHHHHH CS
       AAA_2   7 lllgptgvGktelakalaellfvkkekkliradaselle..eeevehlvsrligappgyvgaeegGivllDEidKihpkessgadvSregVqrdLLqil 103
                 ll gp g+Gkt+ a+a+a+  ++    ++ir+  sel +    e +++v +l      + + ++  i+++DEid i   +        ++Vqr +L ++
  EEA19075.1 129 LLYGPPGTGKTLCARAVANRTDA----TFIRVIGSELVQkyVGEGARMVREL----FEMARTKKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELI 219
                 788******************96....9***999999992222333333333....3455666778**********99633444445579******998 PP

                 H CS
       AAA_2 104 e 104
                  
  EEA19075.1 220 T 220
                 5 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   5.1e-06     0.005       7      51 ..      98     152 ..      95     174 .. 0.71
   2 ?    2.0   0.0      0.23   2.3e+02     124     146 ..     174     200 ..     158     224 .. 0.77

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 5.1e-06
      AAA_16   7 eeleqLlsale.rvrsgrp.........elvllsGesGvGKsslvrellralekd 51 
                 e++e+L++++e ++ s++             ll+G++G+GK+  +r+++++  ++
  EEA19075.1  98 EQIEKLREVVEmPLLSPERfvnlgidppKGALLYGPPGTGKTLCARAVANRTDAT 152
                 5666666666654444444555556666899*****************9754443 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.23
      AAA_16 124 krllallsrderplvlvlDdlq.....w 146
                 ++l++ +++ ++  ++++D+++     +
  EEA19075.1 174 RELFEMART-KKACIIFFDEIDaiggaR 200
                 556677777.777********9555554 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   0.0   2.3e-06    0.0023      52     116 ..     124     193 ..      77     197 .. 0.83

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 2.3e-06
      DUF815  52 pannvLLwGarGtGKSslvkallneyaeegLrli..evekedlkelpklvellr...erperfilfvDDL 116
                 p + +LL+G  GtGK  + +a+ n++ ++ +r+i  e+ ++ + e  ++v++l    ++++ +i+f D +
  EEA19075.1 124 PPKGALLYGPPGTGKTLCARAVANRTDATFIRVIgsELVQKYVGEGARMVRELFemaRTKKACIIFFDEI 193
                 56789*****************************88888999999888888765232678899***9975 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   1.1e-05     0.011      36      94 ..     128     194 ..     122     199 .. 0.66

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1.1e-05
      RuvB_N  36 vllyGpPGlGkttlakiiakelgvkl.kitsgPvleka.gdlaalltnl......eekdvlfideih 94 
                  llyGpPG Gkt  a+ +a+  ++++ ++  +  ++k  g+ a ++ +l      ++  ++f dei 
  EEA19075.1 128 ALLYGPPGTGKTLCARAVANRTDATFiRVIGSELVQKYvGEGARMVRELfemartKKACIIFFDEID 194
                 69*******************9988515555555555325555554444222222344577888875 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   6.3e-05     0.063      26      70 ..     118     154 ..     106     197 .. 0.70

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 6.3e-05
       AAA_7  26 lelllknkkpvllvGptGtGKtviikdllkkldkekylsltinfs 70 
                 ++l ++  k  ll+Gp GtGKt++++ + ++ d         +f 
  EEA19075.1 118 VNLGIDPPKGALLYGPPGTGKTLCARAVANRTD--------ATFI 154
                 56666677889****************999998........3333 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   4.4e-05     0.044       4      40 ..     130     171 ..     128     192 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 4.4e-05
      AAA_28   4 itGgestGKTtlleaLaar....gypvv.pEaareileekla 40 
                 + G+++tGKT  ++a a+r     ++v+  E + +++ e+++
  EEA19075.1 130 LYGPPGTGKTLCARAVANRtdatFIRVIgSELVQKYVGEGAR 171
                 78***************8876656777777777777766553 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   6.8e-05     0.068       3      39 ..     129     167 ..     128     191 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 6.8e-05
      AAA_33   3 llvGlpGsGKstlaerllkklg..avllssdtlrrrlfg 39 
                 ll G+pG+GK+  a+ ++++++  ++++   +l ++++g
  EEA19075.1 129 LLYGPPGTGKTLCARAVANRTDatFIRVIGSELVQKYVG 167
                 578***************999966666666666666655 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   0.00011      0.11       2      62 ..     129     180 ..     128     197 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 0.00011
  RNA_helicase   2 wlyGpsgeGKStlakeLakallkklklkkkdsvysrnpeddfwdgYtgqevvvidDfgqvk 62 
                   +lyGp+g+GK+++a+ +          +++d +++r   ++ +++Y g+ + ++ ++ ++ 
    EEA19075.1 129 LLYGPPGTGKTLCARAV---------ANRTDATFIRVIGSELVQKYVGEGARMVRELFEMA 180
                   69**************3.........45567777788888888888887777777766665 PP

>> AAA_3  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   0.00011      0.11       3      30 ..     129     156 ..     127     189 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00011
       AAA_3   3 llegvPGlaktllvkalakaldlefkri 30 
                 ll g PG++ktl ++a+a+  d++f r+
  EEA19075.1 129 LLYGPPGTGKTLCARAVANRTDATFIRV 156
                 8999*********************998 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00021      0.21       5      22 ..     128     145 ..     125     194 .. 0.89
   2 ?   -3.5   0.0       7.2   7.2e+03      30      59 ..     305     332 ..     303     341 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00021
      AAA_24   5 iliyGpsgiGKTtlakel 22 
                  l+yGp+g+GKT +a+  
  EEA19075.1 128 ALLYGPPGTGKTLCARAV 145
                 589**********99877 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 7.2
      AAA_24  30 dtekGlksldadkfpdieswedfldevvel 59 
                  te+G+ ++ a++  ++ + +dfl +v+++
  EEA19075.1 305 ATEAGMFAIRARR--KVATEKDFLAAVDKV 332
                 5788888888888..567778888777765 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   0.00034      0.34       2      25 ..     129     159 ..     129     231 .. 0.79
   2 ?   -1.8   0.0       4.4   4.4e+03      18      55 ..     289     328 ..     286     343 .. 0.58

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00034
      AAA_18   2 lltGtpGvGKttlakeLskrl.gf......g 25 
                 ll G+pG+GKt  a+++++r+ +       +
  EEA19075.1 129 LLYGPPGTGKTLCARAVANRTdATfirvigS 159
                 589**************99984335655542 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 4.4
      AAA_18  18 Lskrlgf..gvnlrdvakenglllevdpealdeskrlded 55 
                 +s+++ +  g +lr+va+e g+   +   ++  +k +   
  EEA19075.1 289 ISRLCPNatGAELRSVATEAGMFAIRARRKVATEKDFLAA 328
                 4566533478888888888887655555544444444444 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.0    0.0076       7.6      23      46 ..     128     151 ..     120     172 .. 0.80
   2 ?    3.5   0.0     0.059        59     112     136 ..     178     202 ..     161     228 .. 0.76

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0076
    ATPase_2  23 yfiYGpegsGKtaLlkeiienled 46 
                  ++YGp g GKt   + ++++ + 
  EEA19075.1 128 ALLYGPPGTGKTLCARAVANRTDA 151
                 579*********988888887744 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.059
    ATPase_2 112 kikkkgkkiiiiiDelqklidlgln 136
                 ++ +++k  ii++De+  ++   ++
  EEA19075.1 178 EMARTKKACIIFFDEIDAIGGARFD 202
                 67788899********999965555 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   0.00022      0.22       6      76 ..     129     196 ..     125     235 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00022
      AAA_14   6 vitGaRrvGKTtllkqlikellvkkesilyinldderdkkladpekllelileklkeekktylflDEiqev 76 
                 ++ G+  +GKT  ++ ++++       ++ +   +  +k   + +++ ++++e+++++k  ++f+DEi  +
  EEA19075.1 129 LLYGPPGTGKTLCARAVANRTD---ATFIRVIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAI 196
                 789999*******999996666...5555554444444444444467778888765668888******987 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00028      0.27      26      42 ..     129     145 ..     121     152 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00028
  Mg_chelatase  26 llvGppGsGKtmlakrl 42 
                   ll+GppG+GKt+ a+++
    EEA19075.1 129 LLYGPPGTGKTLCARAV 145
                   89************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (349 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       401  (0.022366); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        73  (0.00407162); expected 17.9 (0.001)
Passed Fwd filter:                        18  (0.00100396); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              18  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 2338.95
//
Query:       EEA19076.1  [L=536]
Description: t-complex protein 1, delta subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   7.9e-150  499.7  13.7   8.9e-150  499.5  13.7    1.0  1  Cpn60_TCP1    TCP-1/cpn60 chaperonin family
  ------ inclusion threshold ------
       0.11   12.1   0.1       0.75    9.3   0.0    2.3  2  RNA_Me_trans  Predicted SAM-dependent RNA methyltransferase


Domain annotation for each model (and alignments):
>> Cpn60_TCP1  TCP-1/cpn60 chaperonin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  499.5  13.7  9.9e-154  8.9e-150       1     486 [.      36     532 ..      36     536 .] 0.97

  Alignments for each domain:
  == domain 1  score: 499.5 bits;  conditional E-value: 9.9e-154
                 HHHHHHCCSSTTXXEEEEEETTSEEEEEXSHHHHHHCSXXXSHHHHHHHHHHHHCCCCCTTCHHHHHHHHHHHHHHHHHHHHCTXXHHHHHHHHHHHHH CS
  Cpn60_TCP1   1 ladivkttlGPkGmdKmlvnkggkvvvTnDGatilkeleiehPaakllveaaesqdeevGDGTttvviLageLleeaekliaagvhpttiiegyekale 99 
                 +ad+++t+lGP+GmdKm++n  g++++TnDG+t+lk++ + hPaak+lv+++++qd e+GDGTt+vv++ag+Ll +a +l+++g+hpt i e++++a++
  EEA19076.1  36 VADAIRTSLGPRGMDKMIQNGKGNTIITNDGNTMLKSMSVMHPAAKMLVDLSAAQDIEAGDGTTSVVVIAGSLLGAADRLLSKGIHPTIISEAFQRAAA 134
                 689************************************************************************************************ PP

                 HHHHHHHHHXEEBXSCSTT.HHHHHHHHHHCTTSSXXSTHHHHHHHHHHHH.HCHCCCS.EECSCCCEECCCCEECECTTSEEESEEEESS--SST.TS CS
  Cpn60_TCP1 100 kaleaLkeiaveisseekdreeLlkvartslsskltskeaeelsklvvdAv.klieene.keldlgrikvvkieggsledselveGlvldkgvlsp.dm 195
                 +a+++L  +++ is    dr++Ll++a+tslssk++s++++ l+ ++vd+v k+i+ ++  ++dl  i+++k+ gg +edse+veGlvl++ v+++   
  EEA19076.1 135 AAVNILHDMSQPISL--SDRTALLQAASTSLSSKIVSQHSNLLGPMAVDSVlKVIDPKTaDNVDLRDIRIIKKVGGTIEDSEMVEGLVLNQPVIKSgGG 231
                 *********666665..59*********************************99998889******************************999998788 PP

                 SCEEECEEEEEESS-BS--HHCCHHHCCCCSCCHHHHHHHHHHHHHHHHHHHHHHTTECEEEESS-B.....-HHHHHHHHHCT-EEE-S--HHHHHHH CS
  Cpn60_TCP1 196 pkklenakvllldvsLeiektetkttvvlsdaeeleklekaeekqleellekiiksgvnvvvcqkgi.....ddlalhflakngilalrrvkkkdlerl 289
                 p+++e+a+++l++++L+++k++++ ++v++d  +++k++k+e+++l+++++ki k+++nv+++qk+i     +dl+lhfl + +ila++ ++++++e l
  EEA19076.1 232 PTRIEKARIALIQFQLSPPKPDMENQIVVNDYRQMDKILKEERQYLLNMVKKIQKAKCNVLLIQKSIlrdavNDLSLHFLSRLKILAVKDIERDEVEFL 330
                 ******************************************************************999999*************************** PP

                 HHHHT--EBSCGGGGGCGC-EEEEEEEECCETTCCEEEEECE....SSSSXEEEEEEESTCCCHHHHHHHHHHHHHHHHHHHHHHEEEETTTCHHHHHH CS
  Cpn60_TCP1 290 akatGatavssledltpeelGtakkveeekigsekttiieev....ksgkiatillrgatdtvldeieraiedAlnvvknaiedekvvpGGGatelela 384
                 +k +G++++++++++t+++lGta+ vee + +  ++t i+++    + +++++i+ rga++ +lde+er+++dAl+v++++++++ +++GGGa e+e+a
  EEA19076.1 331 CKSLGCKPIANIDSFTEDKLGTADLVEEVQASGARYTKITGIkssaSTSQTVSIVARGANNLILDEAERSLHDALCVIRCLVKKKALIAGGGAPEIEVA 429
                 ****************************************55444478899************************************************ PP

                 HHHHCCCCTSXCCHHHHHHHHHHHHTHHHHHHHHHCTSXHHHHHHHHHHHHHTTXTTEEEETTTTCEEE.CCCCTXEEEHHHHHHHHHHHHHHHHHHHC CS
  Cpn60_TCP1 385 kklkeyaksvsgeeqlaieafakALevipktLaeNaGldpievlaklraahnkgekelgidvesgeiid.lveagvvDplkvkrqalksAteaastiLr 482
                 ++l+ +a+++sg e+++++afa+A+evip tLaeNaGl++i v+++lr++h++ge ++g++++sg ++d ++e++v++pl v ++a+++A+e++++iLr
  EEA19076.1 430 NQLALKARELSGTEAICWKAFADAMEVIPTTLAENAGLNSIRVVTELRHRHAQGEHNAGVSIRSGGVKDnITEEKVLQPLLVSTSAIELAAETVKMILR 528
                 ********************************************************************9778889************************ PP

                 EEEE CS
  Cpn60_TCP1 483 idei 486
                 id+i
  EEA19076.1 529 IDDI 532
                 ***9 PP

>> RNA_Me_trans  Predicted SAM-dependent RNA methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.0   8.4e-05      0.75      55     106 ..      60     111 ..      29     115 .. 0.77
   2 ?   -0.8   0.0      0.11   9.8e+02     127     169 ..     176     216 ..     148     217 .. 0.74

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 8.4e-05
  RNA_Me_trans  55 elekesveellkelkevkkekvclLDpkaekelspedaeefdvflfGGIlGd 106
                   ++ +++ +++lk+++ ++ +  +l D +a ++++  d+++  v++ G +lG 
    EEA19076.1  60 TIITNDGNTMLKSMSVMHPAAKMLVDLSAAQDIEAGDGTTSVVVIAGSLLGA 111
                   44455556677777777888999***************************97 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.11
  RNA_Me_trans 127 GpvqmttDtAvrvtklvvedkvkleeieyvdepelkfnkkesv 169
                   Gp  m++D  ++v    + d+v+l +i+ ++++   ++++e v
    EEA19076.1 176 GP--MAVDSVLKVIDPKTADNVDLRDIRIIKKVGGTIEDSEMV 216
                   44..889999999999999999999999999887777777666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (536 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       768  (0.0428356); expected 358.6 (0.02)
Passed bias filter:                      544  (0.0303419); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.33s 00:00:00.92 Elapsed: 00:00:00.48
# Mc/sec: 3383.65
//
Query:       EEA19077.1  [L=899]
Description: pheromone maturation dipeptidyl aminopeptidase DapB [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   5.8e-113  377.2   0.5   9.2e-113  376.6   0.5    1.3  1  DPPIV_N        Dipeptidyl peptidase IV (DPP IV) N-terminal re
    1.4e-57  194.6   7.4    1.9e-57  194.1   4.4    2.2  2  Peptidase_S9   Prolyl oligopeptidase family
    4.6e-06   26.4   6.4    0.00015   21.4   3.6    2.8  2  Peptidase_S15  X-Pro dipeptidyl-peptidase (S15 family)
    4.1e-05   23.4   0.6    0.00013   21.7   0.6    1.8  1  Esterase       Putative esterase
    0.00022   21.0   0.5    0.00058   19.6   0.2    1.8  2  Abhydrolase_1  alpha/beta hydrolase fold
    0.00026   20.6   0.0     0.0017   17.9   0.0    2.2  2  DLH            Dienelactone hydrolase family
    0.00065   19.2   0.1       0.22   10.9   0.0    2.7  3  Peptidase_S10  Serine carboxypeptidase
     0.0025   16.8   0.0     0.0039   16.1   0.0    1.2  1  COesterase     Carboxylesterase family
     0.0048   16.7   0.1        1.2    8.9   0.0    2.2  2  Abhydrolase_2  Phospholipase/Carboxylesterase
  ------ inclusion threshold ------
      0.012   14.2   0.0        1.8    7.0   0.0    2.2  2  PAF-AH_p_II    Platelet-activating factor acetylhydrolase, is
      0.025   14.5   0.1        4.7    7.1   0.2    2.4  2  BAAT_C         BAAT / Acyl-CoA thioester hydrolase C terminal


Domain annotation for each model (and alignments):
>> DPPIV_N  Dipeptidyl peptidase IV (DPP IV) N-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  376.6   0.5  5.7e-116  9.2e-113       1     354 []     225     599 ..     225     599 .. 0.98

  Alignments for each domain:
  == domain 1  score: 376.6 bits;  conditional E-value: 5.7e-116
                 TTTSSEEEEEECEEEESSSEETTEEEEEETTTEECEEEETT..TT.BSEEEEESSTTEEEEEETTEEEEESTTTSEEEECES-STTTEEESB--HHHHH CS
     DPPIV_N   1 spdgkflllatnaeknwRhsytaeyyiydletneveelspg..eeklqlakwSPagdklafvrnnnLyvrelatgkeiqlTsdgsagifnGvadWvyeE 97 
                 spd k +l+a na +nwRhs+ta+y+++d+ t+++++l p+  ++++qla wSP++d+++f+r+nnLy+r+l ++k+ qlT+dg +++fnGv+dWvyeE
  EEA19077.1 225 SPDFKSVLVAANAVSNWRHSFTATYWLFDVDTQTAQPLDPDepKGRIQLASWSPQSDAVVFTRDNNLYLRKLDSDKVSQLTKDGGKDVFNGVPDWVYEE 323
                 7999*************************************99******************************************************** PP

                 HTSSSSBEEEE-TTSSEEEEEEEECTTS-EEEEEESSSSC-.........SS-EEEEEE--BTTS---EEEEEEEECTTSCEEECS-HHHHCTTCEEEE CS
     DPPIV_N  98 EvlgsnsavwWspdgsrlaylrfdeseVpeitlpsytdees.........qypevksikYPkaGsknpkVelkvvdlasgktvevqlpdslsekdeyit 187
                 Ev+g++s +wWs dg+++a+lr++es+Vpe+++ +y+++ s         +yp v++ikYPkaGs+np V+l+++d+++ ++++v++++ ++++d++it
  EEA19077.1 324 EVFGTDSTTWWSKDGKYVAFLRTNESMVPEFPIEYYMSRPSgkkppagldKYPDVRKIKYPKAGSPNPVVTLQFYDIENAEVFSVNVSGGFADDDRLIT 422
                 ***************************************99********************************************************** PP

                 EEEECTTSCCEEEEEEETTSTEEEEEEEETTTCCEEEEE....EEESSS-SSS-S-EEE-......TTTSSEEEEEEETTSSEEEEEEESSS-C.EEES CS
     DPPIV_N 188 rvkWtsdeksllvqwlnRsqnrlkvvlvdaetgravvkl....eetsdgWvelhdevhfl......krdesgflwisekdGfkHLylfdldgkseikql 276
                 +v W+s++k +lv+++nR+++ ++ vl+d+ +++ +++      +++ gW e++++++f+      +r ++g+++i+ +dG++H  +f+  ++s +  l
  EEA19077.1 423 EVVWASSGK-VLVKEFNRESDVIRTVLIDVPSRTGELVRvdnfAQDDGGWAEVTQSTTFIpadpanGRPDDGYIDIIVHDGYDHWGYFTPVNNSVPVLL 520
                 *********.******************996666655555679***************************************************9**** PP

                 S-SSS-EEE.EEEEETTTTEEEEEESSSETTEBEEEEEESSCTTEEEESSTTTSEE.EEEEE-TTSSEEEEEEESSSSSE CS
     DPPIV_N 277 TsGeweVts.ilavdekrdlvyFtatkdsPlerhlYsvslesggeltrltdeegdh.ysasfspsgkyyvlkysgpdtpp 354
                 TsG weV +   avd +++ vyF a+k+sP++rh+Ysv+l+ g +l+ ltd ++ + y+asfs  g y++l+y gp +p+
  EEA19077.1 521 TSGPWEVVDtEPAVDLANNIVYFVASKESPTQRHVYSVKLD-GSDLQPLTDVTKAGyYDASFSIGGGYVLLSYDGPRVPW 599
                 *******99899*****************************.*************************************8 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0      0.19   3.2e+02      90     138 ..     230     280 ..     221     292 .. 0.77
   2 !  194.1   4.4   1.2e-60   1.9e-57       3     210 ..     683     886 ..     680     888 .. 0.97

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.19
                   SEEEEESE---CCCHHCSTTS.THH.HCCCC--TTTCHHHHHHHHHH-CGG CS
  Peptidase_S9  90 kaavaevpvvdvlrydsdtdl.lte.eymewgnpeeneegykelspyspld 138
                   +++va+++v++++++ + t   +     + ++   ++++g+ +l+++sp  
    EEA19077.1 230 SVLVAANAVSNWRHSFTATYWlFDVdTQTAQPLDPDEPKGRIQLASWSPQS 280
                   6889**************977866655555555558888888888888865 PP

  == domain 2  score: 194.1 bits;  conditional E-value: 1.2e-60
                   --HHHHHHHCCT-EEEEE--TTSSTTHCHHHHTTSGGGGHHHHHHHHHHHHHHHHTTS--GGGEEEEEETHHHHHHHHHHH.H-GGG-SEEEEESE- CS
  Peptidase_S9   3 fsselqlladrGyvvvvanirGsggyGeafhdagkrklgqnefdDfiaaaealakegyvdserlaitGgSyGGyltgaaln.qrpdlFkaavaevpv 98 
                   ++++ ++++ +Gy+vv +++rG+g+ G+a +  ++++lg +e++D+i+ a+a+ak+ yvd++++ai+G+SyGG++t+ +l+ +++++F++++a+ pv
    EEA19077.1 683 VDFQSYVASTLGYIVVTVDGRGTGHIGRAARTIVRGNLGYWEARDQIETAKAWAKKPYVDKDHIAIWGWSYGGFMTLKTLEqDAGQTFQYGMAVSPV 779
                   5578899999***********************************************************************99************** PP

                   --CCCHHCSTTSTHHHCCCC--TTTCHHHHHHHHHH-CGGG-----EEEEEEETT-SSS-THHHHHHHHHHH--S-S.EEEEEETTS-SSTTSSHHH CS
  Peptidase_S9  99 vdvlrydsdtdllteeymewgnpeeneegykelspyspldnvkaypplLlihGlaDdrvppaealklvaaLqkkgkn.vlllifpdegHgvgkprak 194
                   +d++ yds    +te+ym+++++  n++gy e s++s+++++++++++L++hG+aDd+v+++++l l+++L+ +g++ ++++++pd++H+++ ++a+
    EEA19077.1 780 TDWRFYDSI---YTERYMHTPEH--NPTGY-EHSAISNMTALQQNVRFLVMHGTADDNVHFQNTLSLIDKLDMAGVEnYDVHVYPDSDHSIYFHNAH 870
                   *********...*******7776..*****.****************************************************************** PP

                   HHHHHHHHHHHHHHCT CS
  Peptidase_S9 195 veelarllaFlkealg 210
                   +  + rl ++l  a+ 
    EEA19077.1 871 KMVYDRLSSWLVTAFT 886
                   ***********98875 PP

>> Peptidase_S15  X-Pro dipeptidyl-peptidase (S15 family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   3.6   9.4e-08   0.00015      52     123 ..     608     766 ..     509     791 .. 0.62
   2 ?    4.6   0.1     0.013        21     201     258 ..     789     849 ..     779     863 .. 0.81

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 9.4e-08
                    H.................................................................................HHHTT-EEEEEE-T CS
  Peptidase_S15  52 v.................................................................................fvarGYavVvqdvr 66 
                    +                                                                                     GY+vV +d+r
     EEA19077.1 608 NqnpfeeiieqneqlskmiekyalpaeiyqnitidnvtlqvverrpphfnpvkkypvlfwlyggpgsqsvdrrfsvdfqsyvASTLGYIVVTVDGR 703
                    05555555555555555555555555555555566666666666666666666666666666666666666666666666333445********** PP

                    TSTTS-S---TT.....TTTHHHHHHHHH.HHHHHCTTEEEEEEEEEECHHHHHHHHHCTT-- CS
  Peptidase_S15  67 GtggSeGeftvg.....dsdeaedgadvi.dWlakqpwsnGkVgmtGiSYlGttqllaaatgv 123
                    Gtg+   +  +      ++ ea+d  ++  +W+ k    +++++ +G SY+G++ l  ++++ 
     EEA19077.1 704 GTGHIGRAARTIvrgnlGYWEARDQIETAkAWAKKPYVDKDHIAIWGWSYGGFMTLKTLEQDA 766
                    **996555444469999999*****99983699999******************998887543 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.013
                    HHHCCCC--SSSHHHHTT-HHHHH..CT--S-EEEEEECCSSTTC.CHHHHHHHHHCCTT- CS
  Peptidase_S15 201 veselletgdydafWkdrnlseda..dkvkapvllvgGwnDwnvk.ngaiklyealkapgv 258
                    + +++++t++ ++   ++++ +++   + ++  l+++G +D+nv  ++++ l ++l  +gv
     EEA19077.1 789 YTERYMHTPEHNPTGYEHSAISNMtaLQQNVRFLVMHGTADDNVHfQNTLSLIDKLDMAGV 849
                    678889999999999999999888345556788****************999999887776 PP

>> Esterase  Putative esterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.7   0.6   7.9e-08   0.00013      13     236 ..     651     863 ..     642     871 .. 0.74

  Alignments for each domain:
  == domain 1  score: 21.7 bits;  conditional E-value: 7.9e-08
                 EE.CC.GGTTTEEEEEEE--T...THHCCHHHHHCHHCCCCHCCT.EEEEEECCCSS-TTTTTSBTTSBB.TTEEETTCCCCCCHC..HHHHTHHHHHH CS
    Esterase  13 yLPedyspgrkypvvylldGl...tgwdqnfrakelleslaregeiaeviivvvprggessfysdwdlgarfyenategpgaeaye..tfltqeLlpll 106
                 + P++++p +kypv+++l G    ++ d+ f+++  ++s++++      i+v+v+  g+       + g    ++ t   g+  y+  +   ++   + 
  EEA19077.1 651 RRPPHFNPVKKYPVLFWLYGGpgsQSVDRRFSVD--FQSYVAST--LGYIVVTVDGRGTG------HIG---RAARTIVRGNLGYWeaRDQIETAKAWA 736
                 569999*************977666777777665..44456663..67899999999998......555...445556666666665677778889999 PP

                 HHHCSEECCCEEEEEETHHHHHHHHHHHC.STTTCCEEEEES--S-CC........HCHHHCTTCCHHHCC-CCCCHCHHCHTTSEEEEEEEECTTBCC CS
    Esterase 107 danfrtapdgravaGqSmGGlgALilalk.hpdrFgsvssfSpivnps........namWgqeekeawqendpvllakelsaslkalriyldvGtsedd 196
                 ++ +  ++   a++G S GG++ L +  + + + F++ ++ Sp+ + +          m  +e++++  e+ +++++    a ++++r ++  Gt +d+
  EEA19077.1 737 KKPYVDKDH-IAIWGWSYGGFMTLKTLEQdAGQTFQYGMAVSPVTDWRfydsiyteRYMHTPEHNPTGYEHSAISNM---TALQQNVRFLVMHGTADDN 831
                 999988888.***************9988799************998899888887777777999976666666666...8899999**********96 PP

                 CHTSCHHHHHHHHHHHCCHHHHCCCCCCTT-SCCCC..--SS CS
    Esterase 197 lgeqlsveilevlarnrelkeqlaargvegedheyd..Gghs 236
                 ++ q+          + +l ++l+ +gve +d +++  ++hs
  EEA19077.1 832 VHFQN----------TLSLIDKLDMAGVENYDVHVYpdSDHS 863
                 66333..........334444445555554443333356555 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.2   3.6e-07   0.00058       1      93 [.     663     764 ..     663     782 .. 0.81
   2 ?   -1.6   0.0       1.1   1.7e+03     207     255 ..     809     867 ..     770     869 .. 0.69

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 3.6e-07
                    SEEEEE-STTTCGGG..GTTGHHHHHHHHT.TSEEEEEEETTSTTSSSTTTGB..CHHSHHHHHHHHH....HH.HHHCTTSSEEEEEETHHHHHH CS
  Abhydrolase_1   1 pvlvilhGlpgssdv..waerglapaLakd.gfdvillDlrGvgySspapacin.ddygtasvaddld....ri.ldalgddkltlvGhSmGGmia 87 
                    pvl  l G+pgs  v   +  +++++ a + g+ v+++D rG g+  +a ++i+  + g +  +d ++    ++ +   + d+++++G+S+GG++ 
     EEA19077.1 663 PVLFWLYGGPGSQSVdrRFSVDFQSYVASTlGYIVVTVDGRGTGHIGRAARTIVrGNLGYWEARDQIEtakaWAkKPYVDKDHIAIWGWSYGGFMT 758
                    6778899****55552233333455555558************************99***********88666677778889999**********9 PP

                    HHHHHH CS
  Abhydrolase_1  88 layaae 93 
                    l  +++
     EEA19077.1 759 LKTLEQ 764
                    988876 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 1.1
                    THHHHS.....EEEEEEE.TTCSSSCHHHHHHHHHC....HTSEEEEEEETCSSSHHHH CS
  Abhydrolase_1 207 lknvla.....ptlvisg.tsDplvppkaledlaql....lpkkrlvvisdagHlafle 255
                    ++n++a       lv++g ++D++   + l+ +++l      +  ++v++d+ H +++ 
     EEA19077.1 809 ISNMTAlqqnvRFLVMHGtADDNVHFQNTLSLIDKLdmagVENYDVHVYPDSDHSIYFH 867
                    45555555566888888845555555588888888888888889999999999999885 PP

>> DLH  Dienelactone hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       3.1   5.1e+03      96     111 ..      89     105 ..      73     127 .. 0.76
   2 !   17.9   0.0   1.1e-06    0.0017      83     198 ..     729     875 ..     720     896 .. 0.79

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 3.1
         DLH  96 stkkvgvvG.fCmGGal 111
                  +  + vvG  C+GG++
  EEA19077.1  89 GSRLIWVVGlLCLGGWI 105
                 55667788845999996 PP

  == domain 2  score: 17.9 bits;  conditional E-value: 1.1e-06
         DLH  83 kaavaylksvpevstkkvgvvGfCmGGalalllaaevpevdaavafYG...............................lspekeleeaakikapilal 150
                   + ++++++p+v+++ +++ G+  GG ++l+   ++   ++    YG                                        a + ++  l++
  EEA19077.1 729 IETAKAWAKKPYVDKDHIAIWGWSYGGFMTLKTLEQD---AGQTFQYGmavspvtdwrfydsiyterymhtpehnptgyEHSAISNMTALQQNVRFLVM 824
                 467788999999*******************999988...455666888888899999999*********99998875523333333344455567899 PP

         DLH 151 fgeeDefipadevekleealkaanv.dlelkvYpgagHa..Fandsresyn 198
                 +g++D  + ++++  l  +l  a+v +++++vYp+ +H+  F+n+++  y+
  EEA19077.1 825 HGTADDNVHFQNTLSLIDKLDMAGVeNYDVHVYPDSDHSiyFHNAHKMVYD 875
                 ************9999999999987469**********9777777777555 PP

>> Peptidase_S10  Serine carboxypeptidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.9   0.0   0.00014      0.22      38      56 ..     660     678 ..     649     682 .. 0.83
   2 ?   -2.3   0.0       1.3   2.2e+03     129     148 ..     737     756 ..     725     758 .. 0.78
   3 !    5.1   0.1    0.0078        13     319     370 ..     807     857 ..     783     875 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00014
                    TTS-EEEEE--TTTB-THH CS
  Peptidase_S10  38 eedplvlWLnGGPGCsSld 56 
                    ++ p+++WL GGPG+ S+d
     EEA19077.1 660 KKYPVLFWLYGGPGSQSVD 678
                    556**************87 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1.3
                    HSTCGTTSEEEEEEETTHHH CS
  Peptidase_S10 129 kfpeyksrdfyitGESYaGh 148
                    k p   ++ + i+G SY+G 
     EEA19077.1 737 KKPYVDKDHIAIWGWSYGGF 756
                    567888899*********96 PP

  == domain 3  score: 5.1 bits;  conditional E-value: 0.0078
                    BCHHHHHHHHHTT-EEEEEEETT-STT-HHHHHHHHHHTECTTECCSCCCEE CS
  Peptidase_S10 319 sveeileellesglrvliynGdvDlicnvlgteawikklelsgkkefrpwev 370
                    s+++ ++  l++++r+l+  G +D  + +  t ++i+kl ++g ++++   +
     EEA19077.1 807 SAISNMTA-LQQNVRFLVMHGTADDNVHFQNTLSLIDKLDMAGVENYDVHVY 857
                    44555554.5555***************************999988876555 PP

>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0   2.4e-06    0.0039      51     219 ..     598     777 ..     593     800 .. 0.75

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 2.4e-06
                 --SSEEECBS---BESEECSSSSSCGHHCHHH.........BES---EEEEEE..ESSSSSTTSSEEEEEEE--STTTS-BGCG..S-.THHHHHHHTS CS
  COesterase  51 pwtgvrdAtkfspaCpqnaeksekeekeleaw.........vsEDCLyLnvyt..PkekkeakkklPVlVwihGggfqtgsase..yd.gsaLaaegnv 135
                 pw++v+++ + ++     +e+ e+ +k+ e+          +  D  +L v    P +  +  kk+PVl+w++Gg       ++  +d +s+ a++ + 
  EEA19077.1 598 PWQKVINTPSNQNPFEEIIEQNEQLSKMIEKYalpaeiyqnITIDNVTLQVVErrPPHF-NPVKKYPVLFWLYGGPGSQSVDRRfsVDfQSYVASTLGY 695
                 67777776666655444444444444444333667777777777888888888885554.566677********98777777664444368999999** PP

                 EEEEE---.-HHHHH-B-SSTTSBS-HHHHHHHHHHHHHHHHGGGGTEEEEEEEEEEETHHHHHHHHHHHSGGGTTSBSEEEEES CS
  COesterase 136 ivVtinYR.lGvlGFlstgdeeapGNvGllDqvlALrWVkenIasFGGdpervtlfGesAGaasvsllllsplsrglfkraIlqS 219
                 ivVt+  R  G  G  +     ++GN+G++  +  ++  k   ++   d++++ ++G+s G+ +  l +l + + + f+  ++ S
  EEA19077.1 696 IVVTVDGRgTGHIGRAAR--TIVRGNLGYWEARDQIETAKAWAKKPYVDKDHIAIWGWSYGGFM-TLKTLEQDAGQTFQYGMAVS 777
                 ******995677776655..78********999999999999999999*************986.57778877778888777776 PP

>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.9   0.0   0.00074       1.2      92     124 ..     730     763 ..     724     780 .. 0.84
   2 !    5.3   0.2    0.0091        15     148     202 ..     810     865 ..     802     878 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00074
                    HHHHHHHHTT.--GGGEEEEEETHHHHHHHHHHH CS
  Abhydrolase_2  92 elidaelkkg.ipssriiigGFSqGaalalylal 124
                    e+ +a+ kk+ +++++i+i G S G+ ++l++  
     EEA19077.1 730 ETAKAWAKKPyVDKDHIAIWGWSYGGFMTLKTLE 763
                    66788999999*******************9865 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0091
                    TTS-GGGGG-EEEEEEETT-SSS-HHHHHHHHHHHHTTS-.GEEEEEETT--SS-- CS
  Abhydrolase_2 148 ssatavtkklpilqiHgeeDpvvplalgkaakevlkkllk.kvelksyeglaHsid 202
                    s++ta+++++  l +Hg+ D  v ++    +   l  +   +++ ++y+++ Hsi 
     EEA19077.1 810 SNMTALQQNVRFLVMHGTADDNVHFQNTLSLIDKLDMAGVeNYDVHVYPDSDHSIY 865
                    578888899999*************9988777777766555*************96 PP

>> PAF-AH_p_II  Platelet-activating factor acetylhydrolase, isoform II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.0    0.0058       9.5      61     136 ..     621     703 ..     609     714 .. 0.81
   2 ?    7.0   0.0    0.0011       1.8     222     258 ..     738     776 ..     730     834 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.0058
                  HHHHHHTS-HHHHHHH.HHHHTT-EEEEEET--..B--SS-EEEEEEE--TT--TTTTHHHHHHHHHT.....T-EEEEE--- CS
  PAF-AH_p_II  61 Glsevlkasrlllnllfkllvgslrlpvkknel..lktkekyPlivFsHGLgafRtlYsalcielAsk.....GfvvaavEHr 136
                   ls++++++ l  ++  ++++ +++l+v +  +  +++ +kyP++ +  G  ++ ++   +++++ s+     G++v++v+ r
   EEA19077.1 621 QLSKMIEKYALPAEIYQNITIDNVTLQVVERRPphFNPVKKYPVLFWLYGGPGSQSVDRRFSVDFQSYvastlGYIVVTVDGR 703
                  5888888899999999999999****9998875337788***************99988888776554444469999999876 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0011
                  TT-EEEEEEEEEEETHHHHHHHHHHHH-..TTS-EEEEE CS
  PAF-AH_p_II 222 KdnldtskvaviGHsFGgAtvikslsed..teFrcaial 258
                  K  +d+ ++a+ G s+Gg  ++k+l +d  + F+ ++a 
   EEA19077.1 738 KPYVDKDHIAIWGWSYGGFMTLKTLEQDagQTFQYGMAV 776
                  5668999*********************99999999886 PP

>> BAAT_C  BAAT / Acyl-CoA thioester hydrolase C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.0     0.016        27      14      37 ..     736     759 ..     729     761 .. 0.86
   2 ?    7.1   0.2    0.0029       4.7     113     165 ..     816     866 ..     780     875 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.016
                 HCSTTB--SSEEEEEETHHHHHHH CS
      BAAT_C  14 lrhpkvkkdkigllGiSkGgelal 37 
                  ++p+v kd+i++ G S Gg ++l
  EEA19077.1 736 AKKPYVDKDHIAIWGWSYGGFMTL 759
                 4789****************9886 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0029
                 G--SEEEEEEETT-SSS-HHHHHHHHHHHHHCTT--.--EEEEETTB-S---S CS
      BAAT_C 113 kakgpillvvgedDknwpSkesaekaserLkkagkkvevqlltYpkaGHliep 165
                 + +  +l++ g+ D n+  ++    ++++L  ag + ++ ++ Yp++ H i++
  EEA19077.1 816 QQNVRFLVMHGTADDNVHFQNTL-SLIDKLDMAGVE-NYDVHVYPDSDHSIYF 866
                 458899************99988.8999********.************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (899 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       443  (0.0247086); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.74u 0.33s 00:00:01.07 Elapsed: 00:00:00.47
# Mc/sec: 5764.23
//
Query:       EEA19078.1  [L=411]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.2e-66  222.9   0.8    9.8e-66  222.6   0.8    1.1  1  Questin_oxidase  Questin oxidase-like


Domain annotation for each model (and alignments):
>> Questin_oxidase  Questin oxidase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  222.6   0.8   5.5e-70   9.8e-66       2     340 .]      63     382 ..      62     382 .. 0.87

  Alignments for each domain:
  == domain 1  score: 222.6 bits;  conditional E-value: 5.5e-70
  Questin_oxidase   2 hNHlpHhllAlyalGAsaeqlqaaYeenasyqrpaepspekiteenwrdhLgdeeyyrayldFFedelee..kgwkevleeylfsnegaeells 93 
                      hN +p hl++++ +GA+ ++l+  Y+ ++   +  + +p +   ++w d+Lg++ey ra+ld Fed+l +  ++wk+vl+++lf  +g+++l+s
       EEA19078.1  63 HNFIPQHLISAFLFGADGQTLESLYDLDSRIAEAWKDAPGEVVGSDWMDFLGKKEYERAFLDLFEDDLVDqgYDWKAVLQKFLF--TGEQPLIS 154
                      9****************************855555555544559*************************779************..99****** PP

  Questin_oxidase  94 rlfggllHPlIhlGyglefgqpalvaegLAqaavhydsdpsellsaeaass.raessegs.slleilerilkderldaaarpgnedddkirdgv 185
                      ++ +gl+ PlIhl+ +l+++ + l++e+L +aa++y ++   ++ +++ s+ +ae+ ++s s+ eil++++ der+++ + +   + ++ ++ +
       EEA19078.1 155 SITAGLGQPLIHLALSLQMSVRDLAMEALTLAATSYYDNDV-FKYSDEPSYfQAEPLYKScSISEILHKVRTDERFNSYTIT--IPGEQNMAVI 245
                      ************************************64433.3332223345555666667****************99433..4555566677 PP

  Questin_oxidase 186 lkraadeileyanawkvseeedkeeleekleeliwaatllyaaaglkkepkkpkyDFflmHlvTsslalrsllallpsklspeskarllraywr 279
                      +  +++++l+++naw++s++      ++ ++e+++aa++l++ a+   +    ky+  l+H + +s+a++ +l++ p+k++ +    l++++w+
       EEA19078.1 246 FCDHEAALLDHCNAWTISSD-----PTTYFRESQKAAVALFTGAKI--PAAGGKYNKSLLHPLLMSHAIHLILPHTPDKVHIS----LVQQWWL 328
                      77788************554.....59***************9775..567889************************99999....******* PP

  Questin_oxidase 280 lvllvyvargrpeldldsikeyksaseaelkkgndwktviqrsasaikhdDeHviKlvral 340
                      ++l++yva++rpe+  d i +      +++ +g++w ++ q++ ++ +++D+++  ++r+l
       EEA19078.1 329 TTLAIYVAQLRPEIGFDVIAA------HDT-QGKNWGWIKQQALESQHATDAYFLQTLRVL 382
                      *******************77......444.59*********777889*********9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (411 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       469  (0.0261587); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 2945.93
//
Query:       EEA19079.1  [L=431]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.7e-110  369.4   0.0     2e-110  369.2   0.0    1.0  1  HECT_2    HECT-like Ubiquitin-conjugating enzyme (E2)-binding


Domain annotation for each model (and alignments):
>> HECT_2  HECT-like Ubiquitin-conjugating enzyme (E2)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  369.2   0.0  1.1e-114    2e-110       1     376 []      12     421 ..      12     421 .. 0.93

  Alignments for each domain:
  == domain 1  score: 369.2 bits;  conditional E-value: 1.1e-114
      HECT_2   1 Ellpnirqislfvslpsplae............srksvkvslsedgilivlsheesetlkLParvsesssrsnlelpedask...........elsfrl 76 
                 Ellpnirq++l+vsl ++++e            s+++v+vs++++g+++v      etlkLP++v+ + sr+nl++++++++           e+sfrl
  EEA19079.1  12 ELLPNIRQLTLHVSLLKSASEidlrestitlteSCRAVTVSTHHQGVELV------ETLKLPVKVTDA-SRRNLSFAGHRVDiggaepeaqtaEYSFRL 103
                 9******************88*9988888888877888888888888866......6***********.99********999***************** PP

      HECT_2  77 pldeeessegskdeeslessesekevpWsakdlsaetslrCrsCknvllksrkikr......wkdLPSenwaemmdfWhCHkpdehed.......sede 162
                 ++d+ +++  +  +++l++   + +vpW+a+d+s+ + l+Cr Ck+++++ ++  +      wkdLPS+nwaemmdfWhCHkpd h d        e +
  EEA19079.1 104 QVDP-NDTGLTIPNQVLQD---DDYVPWTASDVSTCVALHCRFCKQTIVDTTSKADtsspwqWKDLPSGNWAEMMDFWHCHKPDVHPDekedqknIEAQ 198
                 ***8.66667777777655...569*************************755544477888**********************999999****99*** PP

      HECT_2 163 naatkgygasnklspqegdglvdltsfllaesdcqglkls...........eetkpkkeeslsCkrCkatlGeedsaaegvkLfkwnvslqpsessesk 250
                 na+ kgygasn++++++ +glvd++sfl+aesdc+g+k++                k+  +l C+rC+a++G+eds aeg++L+k n+s+q+++ +e+ 
  EEA19079.1 199 NASVKGYGASNRVVATPRTGLVDVASFLVAESDCHGIKVLeqrptsnsvksTLYGGKNPMNLGCSRCSAIIGTEDSVAEGLRLYKNNISVQHAGATEDV 297
                 **********************************************9998766778999*****************99****************99987 PP

      HECT_2 251 eesyplesivaaqLleliersgsrkflihsedskekkglllwvfnpdlrvsssssssssleaqramKvlYkdeieeedaeklld.....esdssveele 344
                  e+++++ i ++qLl+li+ +g+r+f+ih ++s   +g+llwvfnpdlr+s sss+++s+ ++ramKvlY+   +++d+e +l+     + ++s+eel 
  EEA19079.1 298 YETHSIDIITSSQLLDLIDHEGVRRFVIHAGQS---DGILLWVFNPDLRYS-SSSANHSIGSRRAMKVLYQ---HVKDVEGILEpengaPTPLSLEELF 389
                 7********************************...***************.*******************...8888888888889************ PP

      HECT_2 345 lpeeiieellevLeesnellPesaRkfkewkv 376
                 lp++i++el+  L++sn l+P saR f+ew+v
  EEA19079.1 390 LPKNIYDELVLSLQRSNLLIPISARIFREWNV 421
                 ******************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (431 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       358  (0.0199677); expected 358.6 (0.02)
Passed bias filter:                      317  (0.0176809); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.25s 00:00:00.72 Elapsed: 00:00:00.47
# Mc/sec: 2772.96
//
Query:       EEA19080.1  [L=237]
Description: hypothetical protein PMAA_013430 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.012   15.8   0.0      0.021   15.0   0.0    1.4  1  Rtt102p   Rtt102p-like transcription regulator protein


Domain annotation for each model (and alignments):
>> Rtt102p  Rtt102p-like transcription regulator protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.0   0.0   1.2e-06     0.021      42      95 ..      20      91 ..       8     122 .. 0.77

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.2e-06
                ..---------B-S--EEEEEE-S....................TT-.---------.----TTCCB--XXXXX CS
     Rtt102p 42 aeesneeneeekysfkyktWlksd....................eaeqkdieeeneeldlldlskydrtkkske 95
                +++ ++e   e y f y++W+ ++                    e   +di++++ +  +++l+++d+ ++ + 
  EEA19080.1 20 NQDYDSECAIEHYDFTYRKWTSKQefislirslstldlpsahhiE-DVQDISADDLK-PIFNLDQFDASNNARG 91
                3467788899**********88888*******9999998766532.33888888877.9********9877544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (237 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       342  (0.0190752); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 1693.01
//
Query:       EEA19081.1  [L=384]
Description: alpha-ketoglutarate-dependent taurine dioxygenase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.2e-60  203.5   2.2    6.5e-60  203.2   2.2    1.1  1  TauD      Taurine catabolism dioxygenase TauD, TfdA family


Domain annotation for each model (and alignments):
>> TauD  Taurine catabolism dioxygenase TauD, TfdA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  203.2   2.2   3.6e-64   6.5e-60       2     268 .]     100     371 ..      99     371 .. 0.91

  Alignments for each domain:
  == domain 1  score: 203.2 bits;  conditional E-value: 3.6e-64
        TauD   2 vkpltpkfgae..gvdlsdleslddelkeelrellaeygvvvfrgfpl...speqqlefarrfGplygtpgrgtntkygevldvssvyesadianlayt 95 
                 v+++tp +g e  gv+ls+   l++  k++l   +a+++vv fr++++     ++ lef  +fG  +++p +g+++ ++e++ v   + +++    ++ 
  EEA19081.1 100 VTEITPYIGSEvrGVQLSQ---LTNTGKDQLALFVAQRKVVAFRDQDFaslPIDKALEFGGYFGRHHIHPTSGAPKGFPEIHLVHRGA-DDNSFLQTFL 194
                 7899*******99999999...66666*******************99999********************************66533.3333332333 PP

        TauD  96 tll.....wHtDlsylesppgiqlLhcleapatGGetpfvDgraaynaLpeelpellegltavrvyyhyrggglrteqelpavdkhprtghpvvrthpv 189
                 + +     wH+D sy+ +ppg+++L+ l  p +GG+t+f++ ++ay++L++e +++l+gl+av++ +++ +      +e++ +++   ++hpvvrthpv
  EEA19081.1 195 HEHtnsvtWHSDVSYERQPPGTTFLYLLDGPTSGGDTLFANLAKAYDRLSPEFKKRLHGLKAVHSGFEQAQ--SALARESTVRRDPVKHEHPVVRTHPV 291
                 33356778***************************************************************..99999999999999***********8 PP

        TauD 190 ltgrkallvnppfatrieglgtpeskelldaleelled.peftyrfqwqeGdlvifdNrrvlHgrt.afdegeeRhllrcy 268
                  tg+ka++vnp+f+++i+g +++es+ ll++l+++++  ++++ r++w +G +v++dNr ++H++  +++ g++Rhl r++
  EEA19081.1 292 -TGEKAIYVNPQFTRYIVGYKKEESDYLLKFLFDHIALsQDLQTRIKWAPGTVVVWDNRVTAHSALyDWENGQRRHLARIT 371
                 .************************************955*****************************999999**9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (384 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       326  (0.0181828); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 2607.06
//
Query:       EEA19082.1  [L=557]
Description: transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      4e-22   78.6  19.6      4e-22   78.6  19.6    1.6  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
          9    4.4  13.7      0.025   12.9   4.0    1.5  2  DUF2070   Predicted membrane protein (DUF2070)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.6  19.6   4.5e-26     4e-22       2     352 ..     102     480 ..     101     481 .. 0.79
   2 ?   -1.7   0.0      0.12   1.1e+03     155     182 ..     500     527 ..     497     541 .. 0.71

  Alignments for each domain:
  == domain 1  score: 78.6 bits;  conditional E-value: 4.5e-26
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgag 100
                 +l++f   l+r++l  a +  + +dlg++   +++  t++++ +++a lp   +s r+G+ r++ + +++++l + + +f ++  ++++ r+  Gl++g
  EEA19082.1 102 CLTFFALQLDRGNLVQATSDNMLTDLGLTTNDYNTGNTIFYVCFLFAELPSQLISKRLGPDRWIPIQMVSWSLIASCQAFLTGRSTFFATRASLGLFEG 200
                 68889999999999999988999***************************************************444445466667************* PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg......Wravfyilaivsllafvlfllllpeepperkrkspkeee..... 188
                 +++p  + +++ w++ +e +  ++++ +++ + ai+g+ l+  +++         Wr++f + ++++ + ++++++++p++p++ +     + +     
  EEA19082.1 201 GFIPDTILFLSYWYTSKELPVRLSFFWSAYEMTAIIGAFLAFGFLHIHTntgtgqWRYLFALEGLITGVIGIFAAFYMPASPTQTAGRFRGKSGwfser 299
                 *************************************888887774444699*********************99999888887766555444458777 PP

       MFS_1 189 ....................kgtgpaplvpawkallkdpvlwillialllfffgfsg....lltllplylqevlglsglllaglllallalvgailall 263
                                     ++++ +p +  ++al+    +w + i  l    ++ +    + ++l l     lg++++ +++l+++++a++++    l
  EEA19082.1 300 eekimvnrvirddpskgsmhNRQAITPKLL-LEALFDYD-MWPIYILGL----VWLIptnpVNSYLSLE-LRSLGFDTFKTNLLTIPAYAMFILN-LGL 390
                 777888888887777776666666666666.77888888.452222222....4444336699999997.9999999767777444444444444.45* PP

       MFS_1 264 agrlsdrlgrrrrlllallllllaalglallavt..ssavllllvlvliGfglgfvfpsllalasdlapp.eeagtasglfntagslggalg 352
                 +++ls +l+   rlll+ ++ +  +++l+ l v   ++++++ +vl+++ +g+  + + + a++s++ +  + +  as+++n++ +++g++g
  EEA19082.1 391 FTWLSEKLNQ--RLLLGAFAEIWNLIFLIALEVLpaNKSTWSRYVLLILLIGSPYMHAVIVAMTSRNSGSvRTRTIASAVYNMTVQASGIIG 480
                 *******887..4444444444444444444444568999999999999999999999999999999955499999**************99 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.12
       MFS_1 155 yilaivsllafvlfllllpeepperkrk 182
                 + +a +sl++f+++ +++  +++ r+rk
  EEA19082.1 500 IGIASLSLFLFLFAKVYYDLKNHYRARK 527
                 5567777777778888887777766665 PP

>> DUF2070  Predicted membrane protein (DUF2070)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.4   2.2      0.47   4.2e+03     114     149 ..     207     256 ..     163     281 .. 0.44
   2 ?   12.9   4.0   2.8e-06     0.025       8     171 ..     333     516 ..     329     555 .. 0.73

  Alignments for each domain:
  == domain 1  score: -4.4 bits;  conditional E-value: 0.47
     DUF2070 114 lrllvlvavsdesllkavlpaliqpllailllvly..............f 149
                 + +l ++ +s+e + + ++  +++ ++ai+ ++l                
  EEA19082.1 207 ILFLSYWYTSKELPVRLSFFWSAYEMTAIIGAFLAfgflhihtntgtgqW 256
                 44444444444444444433333333333333333244444444443322 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 2.8e-06
     DUF2070   8 ifrlPswkvsllliillalligllaflssk.......lfgillfglpalvaflltlpvlrilggrltykrslflalltelivviisllaillsallqal 99 
                 +f  + w + +l ++ l+    + ++ls +        f++ l+++pa + f+l l +  +l+++  +++ l+l +++e+  +i++++  +l a  +++
  EEA19082.1 333 LFDYDMWPIYILGLVWLIPTNPVNSYLSLElrslgfdTFKTNLLTIPAYAMFILNLGLFTWLSEK--LNQRLLLGAFAEIWNLIFLIALEVLPANKSTW 429
                 677777888888888888888888888888899999999***********************888..579999*****999999998888888777888 PP

     DUF2070 100 vllalvlslalvfalrllvlvavsdesllkav..lpaliqpllailllvly.............fspesfllllllslifalavylf 171
                 + + l++ l+ +  +  +++ ++s++s +  +  + ++++++++ +  ++               +++  + ++ lsl+++l++ ++
  EEA19082.1 430 SRYVLLILLIGSPYMHAVIVAMTSRNSGSVRTrtIASAVYNMTVQASGIIGtniyrsddaplylRGNKVLIGIASLSLFLFLFAKVY 516
                 888888888889999999999999987655443366666655555555544777788888776544444444444444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (557 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       450  (0.025099); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.69u 0.37s 00:00:01.06 Elapsed: 00:00:00.57
# Mc/sec: 2944.56
//
Query:       EEA19083.1  [L=555]
Description: hypothetical protein PMAA_013460 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.5e-05   24.7   0.4    3.4e-05   23.7   0.4    1.6  1  F-box-like  F-box-like
     0.0043   16.9   0.3       0.01   15.7   0.3    1.7  1  F-box       F-box domain


Domain annotation for each model (and alignments):
>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.7   0.4   3.7e-09   3.4e-05       1      47 [.      40      87 ..      40      88 .. 0.80

  Alignments for each domain:
  == domain 1  score: 23.7 bits;  conditional E-value: 3.7e-09
  F-box-like  1 isrLPdEiLlqIFsyLppsd...LlrlalVCrrWrrvaldtplLWrrlvl 47
                i+rLP+EiL+ IF++ +++d     +++l+C r++ +  ++ lL r++++
  EEA19083.1 40 ILRLPTEILVSIFEFQDLQDcgsVPNIRLTCQRFCALS-SH-LLIRKVYV 87
                689**********976666433266677*********7.67.99999886 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.3   1.2e-06      0.01       3      37 ..      40      77 ..      38      84 .. 0.92

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 1.2e-06
                HHHS-HHHHHHHHHTS-HHH...HHHHCTT-HHHHHHH CS
       F-box  3 lsrLPsevlrhILerLplsd...llalrrVSkgwrili 37
                ++rLP e+l  I+e+ +l d   + ++r+++ ++  l 
  EEA19083.1 40 ILRLPTEILVSIFEFQDLQDcgsVPNIRLTCQRFCALS 77
                89*******************************98776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (555 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       318  (0.0177366); expected 358.6 (0.02)
Passed bias filter:                      281  (0.0156729); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.70u 0.33s 00:00:01.03 Elapsed: 00:00:00.56
# Mc/sec: 2975.43
//
Query:       EEA19084.1  [L=191]
Description: hypothetical protein PMAA_013470 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
  ------ inclusion threshold ------
       0.15   11.8  13.0        0.2   11.3  13.0    1.1  1  Cwf_Cwc_15  Cwf15/Cwc15 cell cycle control protein


Domain annotation for each model (and alignments):
>> Cwf_Cwc_15  Cwf15/Cwc15 cell cycle control protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3  13.0   1.1e-05       0.2      43     139 ..      74     176 ..      53     183 .. 0.48

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 1.1e-05
                 T--HHHHHHS-HHHHHHHHHHHHHHHHH-------------------------------------..-----------------..........----- CS
  Cwf_Cwc_15  43 qgteeelekrdlraeLeeaeaeakakkrkkaeleaeeeeekekkeeeeeeeeeeakrrkeelleeareidaddedseeeeeeee..........eesdd 131
                  ++e+e++krd  +eL+++e+ ++++ ++  + e+++++   + +e ++e+ ++a   +e++  e ++ d+d+++++e     e          +  ++
  EEA19084.1  74 HKSESESRKRDATKELLREEELYRKECEQ-LGGEDSQNSGWMMVTELRNEAARNAGAAQEQFAYE-NDNDRDSNSESEIGV--EsgtdseseieS--EN 166
                 4667889**********888887777765.55555555433333333333233333333232222.233333333332222..122333333221..11 PP

                 ..-------- CS
  Cwf_Cwc_15 132 ..dsdsdsdd 139
                   +++++sd+
  EEA19084.1 167 gsENENESDS 176
                 1122222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (191 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1072  (0.0597914); expected 358.6 (0.02)
Passed bias filter:                      346  (0.0192983); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.35s 00:00:01.00 Elapsed: 00:00:00.58
# Mc/sec: 991.90
//
Query:       EEA19085.1  [L=282]
Description: glutathione S-transferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.2e-08   33.5   0.0    1.3e-07   31.9   0.0    1.8  2  GST_N_3   Glutathione S-transferase, N-terminal domain
    1.2e-06   28.4   0.0      3e-06   27.1   0.0    1.6  1  GST_C_2   Glutathione S-transferase, C-terminal domain
    6.8e-05   23.0   0.0    0.00012   22.2   0.0    1.4  1  GST_C     Glutathione S-transferase, C-terminal domain
    0.00024   21.3   0.0    0.00053   20.2   0.0    1.6  1  GST_N_2   Glutathione S-transferase, N-terminal domain
  ------ inclusion threshold ------
      0.039   14.2   0.0      0.081   13.1   0.0    1.6  1  GST_C_3   Glutathione S-transferase, C-terminal domain


Domain annotation for each model (and alignments):
>> GST_N_3  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.9   0.0   3.6e-11   1.3e-07       7      74 ..      25     109 ..      20     110 .. 0.80
   2 ?   -2.8   0.0       2.4   8.7e+03      31      51 ..     198     220 ..     191     229 .. 0.67

  Alignments for each domain:
  == domain 1  score: 31.9 bits;  conditional E-value: 3.6e-11
                 SHHHHHHHHHHHHHT--EEEE---..........TTTTHHHHHHH-TT--SSEE......ETT.S-EEESHHHHHHHHHHHH-GG CS
     GST_N_3   7 SpyarrvrlaLnekglpvevvevt..........pgehdeellaknplgkvPvL......edd.gealtdSlaIidyLeelypgp 74 
                 Sp++ +vr +Ln kg+p++  +v+           g    +  +  +l+++P++      +++ ++a+ dSl I+ +L+++++gp
  EEA19085.1  25 SPNTLKVRSVLNIKGIPYTQSWVSypdiaplskgLGIPAKSDNPPGILYTLPAIvhkpsvTINpNGAMNDSLPIALHLDKAFSGP 109
                 9*******************99997777766544333344444445********777776555688****************998 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 2.4
                 TTTT..HHHHHHH-TT--SSEEE CS
     GST_N_3  31 pgeh..deellaknplgkvPvLe 51 
                 +g    ++ lla  + +k P+Le
  EEA19085.1 198 KGALavFDDLLAGGGENKGPFLE 220
                 45444567788888999999996 PP

>> GST_C_2  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.1   0.0   8.4e-10     3e-06       2      54 ..     188     245 ..     187     264 .. 0.86

  Alignments for each domain:
  == domain 1  score: 27.1 bits;  conditional E-value: 8.4e-10
                 HHHCHHHHHCCHCHHHCTTT---SS......CTTCS--HHHHHHHHHHHHHHHHHHS- CS
     GST_C_2   2 aaveraleqldaaldaleahLadsp.....flfGdqptlaDialapflvrlraagpgf 54 
                 ++++ ++e+ + al++++++La++      fl G++p++aD++la++  +++ + p+f
  EEA19085.1 188 EELDKIVEETKGALAVFDDLLAGGGenkgpFLEGEKPGFADVMLAAHMAWMERPLPEF 245
                 67888999**************88888888*********************9998877 PP

>> GST_C  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.2   0.0   3.3e-08   0.00012      18      74 ..     184     245 ..     143     262 .. 0.89

  Alignments for each domain:
  == domain 1  score: 22.2 bits;  conditional E-value: 3.3e-08
                 HHHHHHHHHHHHHHHHHHHHHHHHHH.....TSSSSSTTSSCHHHHHHHHHHHHHHHHTTTT CS
       GST_C  18 ekkeelvdealekvaevlsaleeelk.....kqdylvGdkltlADialvpilnwlqrlglaf 74 
                  k +e++d+  e+++ +l++++  l+     k  +l G+k+++AD+ l++   w++r+ ++f
  EEA19085.1 184 PKTQEELDKIVEETKGALAVFDDLLAgggenKGPFLEGEKPGFADVMLAAHMAWMERPLPEF 245
                 567889************************999***********************998876 PP

>> GST_N_2  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.0   1.5e-07   0.00053       1      69 [.      24     104 ..      24     105 .. 0.73

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 1.5e-07
                 S-HHHHHHHHHHHHCT--EEEEEE...H...-TTSHHHHH..HHHCTTT...SSSEEE-C.TTE......EEESHHHHHHHHHH CS
     GST_N_2   1 aCPwahRvlialalkglediisvv...vlepkgfekseef..prlnprg...tVPvLwdk.dgq......vineSseIlrylet 69 
                 ++P + +v+ +l+ kg++++ s+v   +    + +k+     +  np g   t+P++++k            n+S+ I+  l++
  EEA19085.1  24 WSPNTLKVRSVLNIKGIPYTQSWVsypDI--APLSKGLGIpaKSDNPPGilyTLPAIVHKpS-VtinpngAMNDSLPIALHLDK 104
                 79*********************965322..344444444224444543555*******844.4477888999*****999986 PP

>> GST_C_3  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   2.3e-05     0.081      15      64 ..     183     235 ..     147     251 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2.3e-05
                 CHHH.HHHHHHHHHHHHCHHHHHHHHHH...CHGTSSSSTTS--HHHHHHHHHH CS
     GST_C_3  15 keea.ekkkefleerlpkflkyfekvlk...kkgggylvgdklTyADlalfqvl 64 
                 k ++ e+ ++++e + +  l++f+ +l+   +++g++l g+k  +AD++l + +
  EEA19085.1 183 KPKTqEELDKIVE-ETKGALAVFDDLLAgggENKGPFLEGEKPGFADVMLAAHM 235
                 3333366666665.55679*********98557777************998655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (282 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       334  (0.018629); expected 358.6 (0.02)
Passed bias filter:                      329  (0.0183502); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.62u 0.33s 00:00:00.95 Elapsed: 00:00:00.55
# Mc/sec: 1546.45
//
Query:       EEA19086.1  [L=254]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.1e-43  146.4   0.2    7.6e-43  145.9   0.2    1.3  1  Ribosomal_L37   Mitochondrial ribosomal protein L37


Domain annotation for each model (and alignments):
>> Ribosomal_L37  Mitochondrial ribosomal protein L37
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.9   0.2   4.2e-47   7.6e-43       2     119 ..     116     252 ..     115     253 .. 0.95

  Alignments for each domain:
  == domain 1  score: 145.9 bits;  conditional E-value: 4.2e-47
  Ribosomal_L37   2 skSsvpaGtklkglnilKnkadpvaleDseYPeWLWtlldsa.kkak.....dlsskskkarklakkklaakeaelakkipleeqsidlpaeet.. 89 
                    ++Ss+ aGt+lkgln++K k+d+valeD+eYP+WLWtlld++ kk +     d+ s +kk+rk+++kk+aa++a++++kipl+eq++d+ ++e+  
     EEA19086.1 116 EPSSCVAGTPLKGLNYTKGKQDIVALEDHEYPDWLWTLLDDSaKKGNdaggvDVASLNKKQRKRHEKKMAALAATQPRKIPLHEQATDIIPAEYng 211
                    68**************************************9766666899****************************************77777* PP

  Ribosomal_L37  90 ...........aeeaaeareelkkalrkkrrakIkesNflk 119
                               a+  +e+  +++k++r++rr+ I+esNfl+
     EEA19086.1 212 eqdgprdilaeAAAGIEKTGQITKSAREARRKGIRESNFLR 252
                    *********999999*************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (254 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       641  (0.0357521); expected 358.6 (0.02)
Passed bias filter:                      440  (0.0245412); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.35s 00:00:01.00 Elapsed: 00:00:00.59
# Mc/sec: 1304.01
//
Query:       EEA19087.1  [L=358]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-23   83.6   0.2    4.1e-20   72.1   0.2    2.7  2  adh_short     short chain dehydrogenase
    5.6e-11   42.4   0.2    9.3e-09   35.2   0.1    2.7  2  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
    0.00029   20.8   0.0    0.00067   19.6   0.0    1.5  2  KR            KR domain
     0.0095   15.3   0.0      0.014   14.8   0.0    1.2  1  DUF1776       Fungal family of unknown function (DUF1776)


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.1   0.2   9.2e-24   4.1e-20       2     139 ..      17     170 ..      16     176 .. 0.85
   2 !    8.5   0.0   0.00028       1.2     147     187 ..     200     245 ..     193     253 .. 0.75

  Alignments for each domain:
  == domain 1  score: 72.1 bits;  conditional E-value: 9.2e-24
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHH....HHHHHHHHHT.........TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---S CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekl....eevakelkee.........gakalaiqvDvtdreevealvekavkklgkldvLvnNAGi 87 
                 v++vtG+++GIG++++  la +Ga+v++++r +e      e v + lke+         ++++ + ++D+ +++++ +  ++ + + g+ld+Lv NAG+
  EEA19087.1  17 VAIVTGGAKGIGLETSVYLALKGATVYIAARDSEGTlagiEDVRERLKEKcapndnldtESRIKYHELDLGSMHKAWKSAREFARNEGRLDILVCNAGV 115
                 89**************************9998876511113444444444444344555667***********99999999999*************** PP

                 S--SSGGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHH....HCTTEEEEEEEEGGG CS
   adh_short  88 tgsgpfselseeewervievNltgvflltravlpaml....kqssGrIvnvsSvag 139
                   ++++++ls + ++ ++ vN  g f  t+ +l+ ++      + GrIv++ S+a 
  EEA19087.1 116 -SMTTMQQLSPDGFDTMFTVNHLGHFAFTAGLLDLIKqtseTTQDGRIVFTNSNAY 170
                 .799999****************************9988888999********985 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00028
                 HHHHHHHHH....HHHHHHHHHHHHGGGTEEEEEEEESSBS.SHHH CS
   adh_short 147 aaYsAsKaa....vagltrslakelaptgirvnavaPGlvd.Tdma 187
                   Ys sK a    v  l++ l+++l  t+i +n+++PG    T++ 
  EEA19087.1 200 KRYSESKLAalygVLELSHRLHNQLGLTNIYINSCHPGNAIgTALG 245
                 5677777542222899**********************75436665 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.2   0.1   2.1e-12   9.3e-09       1     130 [.      22     169 ..      22     178 .. 0.85
   2 !    3.9   0.0    0.0076        34     146     215 ..     211     283 ..     195     288 .. 0.75

  Alignments for each domain:
  == domain 1  score: 35.2 bits;  conditional E-value: 2.1e-12
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGH.HHHHHHHHHHTTSE.E.............EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EG CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneea.kkrveelaeelgae.v.............lecDVtdeeqvealveevvekfgklDilvnnagiapk 82 
                   G a+gIG ++   la +Ga+v ++ ++ e+  + +e++ e+l+++ +              e+D  +  +  + ++e +++ g+lDilv nag++ +
    EEA19087.1  22 GGAKGIGLETSVYLALKGATVYIAARDSEGtLAGIEDVRERLKEKcApndnldtesrikyHELDLGSMHKAWKSAREFARNEGRLDILVCNAGVSMT 118
                   6689************************998888888888887553244444555566778999999999999999999999**************9 PP

                   CSS-GGGH-HHHHHHHHHHHTHHHHHHHHHHHHHCTSC......CEEEEEEEGG CS
  adh_short_C2  83 lkgpfletsreefdraldvnlyslfllakaalplmkeg......gsivnlssvg 130
                       + ++s ++fd+++ vn  + f+++  +l l+k++      g+iv + s +
    EEA19087.1 119 ---TMQQLSPDGFDTMFTVNHLGHFAFTAGLLDLIKQTsettqdGRIVFTNSNA 169
                   ...8899**************************888776777888899888765 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.0076
                   HHHHHHHHHHHHHHGGGTEEEEEEEE-.-BHCTGGGGSTT.HHHHHHHHHHHSTTSS-B.-HHHHHHHHHHHC CS
  adh_short_C2 146 aalealtrylAvelgpkgiRvNavspg.pikTlaasgikg.fdelleelearaplgrlg.tpeevaeaalfLa 215
                    ++  l++ l ++lg  +i +N+ +pg +i T + +g ++  ++ le++ +      +g ++ + a++ ++La
    EEA19087.1 211 YGVLELSHRLHNQLGLTNIYINSCHPGnAIGTALGQGHQKgVNQTLERIVRAGLQVTIGnSTADSAKTQVYLA 283
                   589999999*****************95799999888766466666666555554455557888888888887 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.0   1.5e-07   0.00067       4     110 ..      19     133 ..      17     150 .. 0.77
   2 ?   -3.5   0.0       1.9   8.6e+03      66      92 ..     193     220 ..     183     224 .. 0.73

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 1.5e-07
                 EEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..........--HHHHHHHHHHHHTT-.........EEEE----TT-HHHHHHHHHHHHHHSS---EE CS
          KR   4 litGGlGgLGlelarwlaekgarhlvllsRsa........aadedskaliaelealga.........evevvaaDvsdkdavealleeikaeeppikGv 85 
                 ++tGG+ g+Gle++  la kga+ + + +R++                  ++l+++ a         ++++ ++D+ + ++  +  +e+ ++e+++   
  EEA19087.1  19 IVTGGAKGIGLETSVYLALKGAT-VYIAARDSegtlagieD-------VRERLKEKCApndnldtesRIKYHELDLGSMHKAWKSAREFARNEGRLDIL 109
                 8********************96.66677776566654442.......2222222222333344455******************************** PP

                 EE---------TTT--HHHHHHHHT CS
          KR  86 ihaAgvlrdklleemtaedleqvla 110
                 +  Agv+++ ++++++ + +++++ 
  EEA19087.1 110 VCNAGVSMT-TMQQLSPDGFDTMFT 133
                 *****9875.567888888877765 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 1.9
                 HHHHHHHHHHHHHS.S---EEEE----- CS
          KR  66 davealleeikaee.ppikGvihaAgvl 92 
                 ++v+++++++++++ +++ Gv+     l
  EEA19087.1 193 KDVSNAFKRYSESKlAALYGVLELSHRL 220
                 6788888888888888888888776555 PP

>> DUF1776  Fungal family of unknown function (DUF1776)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0     3e-06     0.014      27     158 ..      38     171 ..      31     229 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 3e-06
     DUF1776  27 rGFiVfvtvesaeeeklvesedredIrplsvdddpssieasleefaqslesphvalpgakphvl...rLkgvilvPslsyptgpietiplsswaselne 122
                 +G +V++ ++++e + +  ++ re  ++++  +d+  +e++++    +l s h a + a +++    rL   ilv +   +++ +++++++ +   ++ 
  EEA19087.1  38 KGATVYIAARDSEGTLAGIEDVRERLKEKCAPNDNLDTESRIKYHELDLGSMHKAWKSAREFARnegRLD--ILVCNAGVSMTTMQQLSPDGFDTMFTV 134
                 8889*****9999777777666999999999999***********************9999875211443..999999998899*************** PP

     DUF1776 123 rllspiltlqallplltsra..kqkakiivvnpsisss 158
                 + l  ++++ +ll l+++++  +q  +i++ n s   +
  EEA19087.1 135 NHLGHFAFTAGLLDLIKQTSetTQDGRIVFTN-SNAYK 171
                 ******************99754555555555.54444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (358 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       491  (0.0273858); expected 358.6 (0.02)
Passed bias filter:                      431  (0.0240393); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.65u 0.39s 00:00:01.04 Elapsed: 00:00:00.56
# Mc/sec: 1920.73
//
Query:       EEA19088.1  [L=475]
Description: GABA permease GabA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      3e-50  171.3  44.2      4e-50  170.9  44.2    1.0  1  AA_permease_2  Amino acid permease
    1.7e-20   73.1  37.1    2.3e-20   72.6  37.1    1.1  1  AA_permease    Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  170.9  44.2   4.5e-54     4e-50       1     396 [.      28     440 ..      28     448 .. 0.85

  Alignments for each domain:
  == domain 1  score: 170.9 bits;  conditional E-value: 4.5e-54
  AA_permease_2   1 lsllsafalvigsv.igsgifvknlaasggpalilwvwiavligslavllvyaEl.ssalprsgGiyvytkaafg...kkvaflsawfnwfayvpv 91 
                    ls+l++++ +++s  + s+++   ++ sgg ++++w++i+++i+ l+ ++ +aE+ s   p+ gG+y++++  ++   +++ ++++w+n+ ++++ 
     EEA19088.1  28 LSMLGLAFAILNSWtALSASMSL-SLPSGGSTSVVWGLITAGICNLCIAASLAEFlSM-YPTAGGQYHWVAVSWPnwvPVLSWITGWINVAGWIAL 121
                    78999999999997355777766.7889***************************777.**************973336666*******9999998 PP

  AA_permease_2  92 lasilsvaasyllna...lgpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfsslstetdtffp 184
                    +a+   +a + +l++   ++pd++ ++w+++li+i+  i  ++in++  + +  ++   +i++i+  ++i+ i++l+  +++++s      +  + 
     EEA19088.1 122 VATAGLLASQLILGVislMNPDYVSQRWHQFLIYIGYNIAAFIINAFMNSALPLVTRAAFIWSIT-GFAIVSITVLACSSPNYNSGDFVFREFLNE 216
                    887777788888666222689*******************************************6.6699999999999*****976444445777 PP

  AA_permease_2 185 ngwp.gv..llgllivlwsfdGfesaanvseevkk.k.dvpkaifigllivlvlyllvniaflgvvpd.deianlsnlgsvaalffeavggkvvai 274
                    +gwp g+  llgll+  + ++G++++a++ ee+++ +   pk +++++ i ++ + ++ i++l+v +  d i ++s  g +++++ +a+ + ++ai
     EEA19088.1 217 TGWPdGIawLLGLLQGGLGVTGYDAVAHMIEEIPNaAiEGPKIMIYCVCIGTFTGAVFLIVLLFVPGNiDDIISSSA-GPLLQILDNATKNHAGAI 311
                    79997545599************************7458*************************9776666655444.45789999999999**** PP

  AA_permease_2 275 ivvilialsllgaintavigssrvlealardgvlP..rffakvn.kfgspiraiiltaivslillllfllassaaynfllsvsslgliisylllii 367
                     + ++  ++ll+a++t ++++sr+++a+ardg+lP  rffa+v+ + + p++a+ lt i ++i++l+fl+ ss+a+n++ s+s+++l isy+++i 
     EEA19088.1 312 CLLMVPLVCLLFAAITIMTTCSRMVYAFARDGGLPasRFFARVHkRLNVPLNALYLTTIMVIIFGLIFLG-SSSAFNAIISASVVALDISYGMPIM 406
                    **9999**************************************889**************999888876.58*********************95 PP

  AA_permease_2 368 galilrkkrphlkr.pgk.....ilvaiigalfll 396
                      ++  ++  ++   +++     ++ +i+++++ l
     EEA19088.1 407 INVMRGRR-MIKDSpWKMseplaWTANIVSIILQL 440
                    55543333.33333233355555888888877655 PP

>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.6  37.1   2.6e-24   2.3e-20       5     401 ..      35     423 ..      31     448 .. 0.82

  Alignments for each domain:
  == domain 1  score: 72.6 bits;  conditional E-value: 2.6e-24
  AA_permease   5 ialggviGtglfvglgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflg...pelGfviGlnylfswit.vlaleltaas 98 
                  +a+++ + t+l  +++  l ++G  +++ +++ ag++ ++++ sl+e+ +++p +gg y++++ ++    p l++ +G++ +  wi+ v++++l a++
   EEA19088.1  35 FAILNSW-TALSASMSLSLPSGGSTSVVWGLITAGICNLCIAASLAEFLSMYPTAGGQYHWVAVSWPnwvPVLSWITGWINVAGWIAlVATAGLLASQ 131
                  6777766.889999*************************************************98651116789******999999725567888999 PP

  AA_permease  99 iliqfwel.vtdlpkawvt..gavflvvlliinlvgvkvygeaefilalikiiaiiafiivg.iillaggkpnkga..gfrflgdngsifknnlppgf 190
                   +++ ++l ++d+     +   ++ +++ ++  ++++ +  +  +++    i +i +f iv+  +l ++  + +     fr + ++++      p+g 
   EEA19088.1 132 LILGVISLmNPDYV-SQRWhqFLIYIGYNIAAFIINAFMNSALPLVTRAAFIWSITGFAIVSiTVLACSSPNYNSGdfVFREFLNETG-----WPDG- 222
                  99999977666665.3333558888888888888888888888888888888889999999965666665555553566666666666.....5666. PP

  AA_permease 191 akeeegafknfisvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasaaspfvifikesgvsvl 288
                           +++ ++ +  ++ tG+ +va + +E+ + +   Pk +++ v + t+     +l++ l vp n ++++++sa +  ++ i  + +++ + 
   EEA19088.1 223 --------IAWLLGLLQGGLGVTGYDAVAHMIEEIPNAAIEGPKIMIYCVCIGTFTGAV-FLIVLLFVPGNIDDIISSSAGP--LLQILDNATKNHAG 309
                  ........78999*******************************999999988877754.44566789*********99966..99999999999999 PP

  AA_permease 289 aplinaviltaalssansslysasRvlyslakdglaP...kvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwll. 382
                  a  + +v l+ +l++a+ +++++sR++y++a+dg +P   ++++++++ +vPl+a++l++i++ ++ l+   +++   +fn ++++s ++  i +++ 
   EEA19088.1 310 AICLLMVPLVCLLFAAITIMTTCSRMVYAFARDGGLPasrFFARVHKRLNVPLNALYLTTIMVIIFGLIFLGSSS---AFNAIISASVVALDISYGMp 404
                  9999***********************************9999999999******************88765555...89988888888877777775 PP

  AA_permease 383 iilsylrfRkalkyqgrsi 401
                  i+++ +r R+ +k + +++
   EEA19088.1 405 IMINVMRGRRMIKDSPWKM 423
                  7888888888877776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (475 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       859  (0.0479112); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.38s 00:00:01.05 Elapsed: 00:00:00.57
# Mc/sec: 2516.14
//
Query:       EEA19089.1  [L=1452]
Description: peroxisome biosynthesis protein (PAS8/Peroxin-6), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.7e-51  174.1   0.0    2.6e-43  147.6   0.0    2.6  2  AAA           ATPase family associated with various cellular 
    1.5e-08   34.3   8.0    9.5e-05   22.1   0.2    3.0  3  AAA_lid_3     AAA+ lid domain
    5.8e-05   23.5   0.0      0.023   15.1   0.0    3.5  3  AAA_16        AAA ATPase domain
    7.9e-05   22.5   0.0    0.00042   20.1   0.0    2.2  2  RuvB_N        Holliday junction DNA helicase RuvB P-loop doma
    0.00058   19.0   0.0    0.00096   18.3   0.0    1.2  1  Parvo_NS1     Parvovirus non-structural protein NS1
     0.0012   19.2   0.1      0.016   15.6   0.0    2.7  2  RNA_helicase  RNA helicase
     0.0031   17.7   0.0     0.0085   16.2   0.0    1.8  1  AAA_2         AAA domain (Cdc48 subfamily)
     0.0032   17.6   0.0       0.45   10.7   0.0    2.9  2  AAA_33        AAA domain
     0.0035   16.9   0.1      0.043   13.4   0.0    2.8  2  AAA_25        AAA domain
     0.0044   17.3   0.0      0.046   14.0   0.0    2.8  2  AAA_22        AAA domain
     0.0067   15.7   0.0      0.012   14.8   0.0    1.3  1  TIP49         TIP49 P-loop domain
     0.0087   15.8   0.0      0.019   14.7   0.0    1.5  1  IstB_IS21     IstB-like ATP binding protein
  ------ inclusion threshold ------
      0.017   15.7   0.0       0.12   12.9   0.0    2.4  2  AAA_18        AAA domain
      0.023   14.1   0.1      0.051   12.9   0.1    1.5  1  Mg_chelatase  Magnesium chelatase, subunit ChlI
      0.026   14.5   0.1       0.16   12.0   0.0    2.1  2  TsaE          Threonylcarbamoyl adenosine biosynthesis protei
      0.032   14.2   0.0       0.13   12.3   0.0    2.1  1  AAA_5         AAA domain (dynein-related subfamily)
      0.037   13.4   0.0      0.082   12.2   0.0    1.5  1  ATPase        KaiC
      0.043   13.3   0.0      0.087   12.3   0.0    1.4  1  AAA_7         P-loop containing dynein motor region
       0.08   13.0   0.0        1.9    8.6   0.0    2.5  2  AAA_14        AAA domain
       0.09   12.2   0.0       0.21   11.0   0.0    1.6  1  PhoH          PhoH-like protein
      0.094   13.0   0.0       0.31   11.3   0.0    1.9  1  AAA_28        AAA domain
        0.1   12.3   0.1       0.96    9.1   0.1    2.2  2  AAA_24        AAA domain
       0.12   11.5   0.0        3.1    6.9   0.0    2.5  3  NB-ARC        NB-ARC domain
       0.36   11.5   2.1        1.5    9.5   2.1    2.1  1  MAGE_N        Melanoma associated antigen family N terminal


Domain annotation for each model (and alignments):
>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.7   0.2   6.9e-08   5.2e-05       9     129 ..     797     906 ..     789     909 .. 0.78
   2 !  147.6   0.0   3.5e-46   2.6e-43       1     130 [.    1060    1194 ..    1060    1196 .. 0.96

  Alignments for each domain:
  == domain 1  score: 23.7 bits;  conditional E-value: 6.9e-08
                 SSHHHHHHHHHHHHTHEEEEEETTTCS.SSSTTHHHHHHHHHHHHHHHTS......TSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTSS CS
         AAA   9 tGKTllakavakelgvefleisgsell.skyvgesekkirelfkeakeka......kpsilfiDEidalaksrsgseseeeervvnqLlteldgvkkke 100
                 +GKT+la+  + e+g + ++i++ ++l +     +  k+++++k+ ++ +      + + l+i  id l+ +r              ++t++++   + 
  EEA19089.1 797 IGKTTLASRACAEIGLHAFTIDAYDILtEGGANGGDVKTEAYMKA-RADRalacgpNSTALIIQHIDVLTADR--------------IVTAMKEIVAE- 879
                 7**************************444556666666666665.3333478977669**********9999..............66666666653. PP

                 STEEEEEEESSGGGSTHHHHSTTSSEEEE CS
         AAA 101 skvivigatnrpdkldpallrgRfdrkie 129
                    ++i++t+++dk+++ ++ + f++++e
  EEA19089.1 880 -SRVIIATTTDVDKIPEGIR-SLFTHELE 906
                 .2479***************.99988776 PP

  == domain 2  score: 147.6 bits;  conditional E-value: 3.5e-46
                  EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHH..TTCCCHHHHHHHHHHHHHHHH CS
         AAA    1 vllyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksr..sgseseeeervvnqLlteldg 95  
                  +l+yGppGtGKTllaka+a+e++ +f++++g+ell++y+gese+++r +f++a+  + p+++f+DE+d++a++r  +g++ ++ +r+v+qLl+eldg
  EEA19089.1 1060 ILFYGPPGTGKTLLAKAIATEFSLNFFSVKGPELLNMYIGESEANVRRVFQRARDAR-PCVVFFDELDSVAPKRgnQGDSGGVMDRIVSQLLAELDG 1155
                  69****************************************************998.****************9888899**************** PP

                  TTTS...SSTEEEEEEESSGGGSTHHHHS.TTSSEEEET CS
         AAA   96 vkkk...eskvivigatnrpdkldpallr.gRfdrkiei 130 
                  ++      + v+vigatnrpd ld allr gRfd+ i++
  EEA19089.1 1156 MSGGdenGGGVFVIGATNRPDLLDAALLRpGRFDKMIYL 1194
                  *998777666*************************9997 PP

>> AAA_lid_3  AAA+ lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   1.6   2.3e-05     0.017       1      36 [.     933     968 ..     933     981 .. 0.91
   2 ?   -3.1   0.0       9.4     7e+03       6      18 ..    1148    1160 ..    1146    1160 .. 0.77
   3 !   22.1   0.2   1.3e-07   9.5e-05       1      39 [.    1219    1258 ..    1219    1263 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 2.3e-05
   AAA_lid_3   1 dvdlkeLAerTeGySGADlaalcreAallAlrrgik 36 
                 dvdl+++A +T+  +  Dl+ ++ +A+l+ l+r +k
  EEA19089.1 933 DVDLAAVAVKTAALVAGDLVDVVERASLAKLDRLEK 968
                 9*******************************9877 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 9.4
   AAA_lid_3    6 eLAerTeGySGAD 18  
                  +L ++ +G+SG D
  EEA19089.1 1148 QLLAELDGMSGGD 1160
                  5556789****88 PP

  == domain 3  score: 22.1 bits;  conditional E-value: 1.3e-07
   AAA_lid_3    1 dvdlkeLAerTeG.ySGADlaalcreAallAlrrgikeit 39  
                  dv+l+++Aer +  y+GADl alc  A l A+ r  ++++
  EEA19089.1 1219 DVSLARVAERLPFtYTGADLYALCSDAMLKAITRQATAVD 1258
                  9***********77******************99877766 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0       4.4   3.3e+03      28      48 ..     790     810 ..     765     824 .. 0.71
   2 !   15.1   0.0   3.1e-05     0.023      25      51 ..    1058    1084 ..    1047    1098 .. 0.81
   3 ?    4.0   0.0     0.081        60     124     147 ..    1106    1128 ..    1099    1170 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 4.4
      AAA_16  28 llsGesGvGKsslvrellral 48 
                 l s ++ +GK++l+ ++  ++
  EEA19089.1 790 LTSTQRHIGKTTLASRACAEI 810
                 44556779*****96665555 PP

  == domain 2  score: 15.1 bits;  conditional E-value: 3.1e-05
      AAA_16   25 elvllsGesGvGKsslvrellralekd 51  
                  + +l++G++G+GK+ l+++++++++ +
  EEA19089.1 1058 SGILFYGPPGTGKTLLAKAIATEFSLN 1084
                  789*****************9987655 PP

  == domain 3  score: 4.0 bits;  conditional E-value: 0.081
      AAA_16  124 krllallsrderplvlvlDdlqwa 147 
                  +r +++++  +rp v+++D+l+ +
  EEA19089.1 1106 RRVFQRARD-ARPCVVFFDELDSV 1128
                  666778887.***********954 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       4.2   3.1e+03      40      58 ..     793     811 ..     763     818 .. 0.69
   2 !   20.1   0.0   5.6e-07   0.00042      34      69 ..    1058    1093 ..    1025    1128 .. 0.88

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 4.2
      RuvB_N  40 GpPGlGkttlakiiakelg 58 
                     +Gkttla+  ++e+g
  EEA19089.1 793 TQRHIGKTTLASRACAEIG 811
                 3456788888887777766 PP

  == domain 2  score: 20.1 bits;  conditional E-value: 5.6e-07
      RuvB_N   34 dhvllyGpPGlGkttlakiiakelgvklkitsgPvl 69  
                    +l+yGpPG Gkt lak ia+e+  ++ +  gP l
  EEA19089.1 1058 SGILFYGPPGTGKTLLAKAIATEFSLNFFSVKGPEL 1093
                  469*************************99999976 PP

>> Parvo_NS1  Parvovirus non-structural protein NS1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   1.3e-06   0.00096     107     138 ..    1050    1081 ..    1045    1084 .. 0.88

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 1.3e-06
   Parvo_NS1  107 lskqlgkrntvwfyGpantGktnlaeaIakav 138 
                  + k + kr  ++fyGp+ tGkt la+aIa+ +
  EEA19089.1 1050 FAKGMKKRSGILFYGPPGTGKTLLAKAIATEF 1081
                  667789**********************9865 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0       1.9   1.4e+03       6      24 ..     794     812 ..     788     836 .. 0.77
   2 !   15.6   0.0   2.1e-05     0.016       1      47 [.    1060    1109 ..    1060    1155 .. 0.71

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 1.9
  RNA_helicase   6 psgeGKStlakeLakallk 24 
                   ++++GK+tla + ++++  
    EEA19089.1 794 QRHIGKTTLASRACAEIGL 812
                   4599******998888764 PP

  == domain 2  score: 15.6 bits;  conditional E-value: 2.1e-05
  RNA_helicase    1 iwlyGpsgeGKStlakeLakallkkl...klkkkdsvysrnpeddfwdgY 47  
                    i++yGp+g+GK++lak +a++++ ++   k ++  ++y++++e ++   +
    EEA19089.1 1060 ILFYGPPGTGKTLLAKAIATEFSLNFfsvKGPELLNMYIGESEANVRRVF 1109
                    789******************99666566667777777777766654444 PP

>> AAA_2  AAA domain (Cdc48 subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   1.1e-05    0.0085       3      90 ..    1057    1138 ..    1055    1163 .. 0.69

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.1e-05
                  ---EEEE--TTSSHHHHHHHHHHHTT-....-EEEEEGGG-------THHHHHHHHHTTT-HHHH.TTS......EEEEETGGG----------- CS
       AAA_2    3 iisilllgptgvGktelakalaellfvkkekkliradaselleeeevehlvsrligappgyvgae.egG......ivllDEidKihpkessgadv 90  
                   + il+ gp g+Gkt+laka+a   ++    ++  +   ell          + ig+++++v++  ++       +v++DE+d ++pk+ ++ d 
  EEA19089.1 1057 RSGILFYGPPGTGKTLLAKAIATEFSL----NFFSVKGPELLN---------MYIGESEANVRRVfQRArdarpcVVFFDELDSVAPKRGNQGDS 1138
                  5679*********************97....777766666666.........44444444443221222444678************84444443 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0       0.1        76      10      53 ..     797     844 ..     795     870 .. 0.74
   2 !   10.7   0.0   0.00061      0.45       2      38 ..    1060    1098 ..    1060    1119 .. 0.76

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.1
      AAA_33  10 sGKstlaerllkklg..avllssdtlrrrlfg..tdqqsktdytrvld 53 
                  GK+tla r +++ g  a++++  ++++   +   d++++ + +  +d
  EEA19089.1 797 IGKTTLASRACAEIGlhAFTIDAYDILTEGGAngGDVKTEAYMKARAD 844
                 6************99999999998888854441244444444444444 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 0.00061
      AAA_33    2 vllvGlpGsGKstlaerllkklg..avllssdtlrrrlf 38  
                  +l+ G+pG+GK+ la+ ++ +    ++ +  ++l++++ 
  EEA19089.1 1060 ILFYGPPGTGKTLLAKAIATEFSlnFFSVKGPELLNMYI 1098
                  6899*************9987766666677776666555 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0       1.8   1.3e+03      36      56 ..     789     809 ..     763     814 .. 0.76
   2 !   13.4   0.0   5.8e-05     0.043       8      65 ..    1033    1087 ..    1029    1157 .. 0.69

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 1.8
      AAA_25  36 allaGapgtGKttlaldlala 56 
                  l   ++  GKttla+  +++
  EEA19089.1 789 LLTSTQRHIGKTTLASRACAE 809
                 455567789******998886 PP

  == domain 2  score: 13.4 bits;  conditional E-value: 5.8e-05
      AAA_25    8 savsvadlaapppprrwlvkgllpagelallaGapgtGKttlaldlalavatGkpwlg 65  
                  ++++++ ++ p+++++   kg+  + + +l++G+pgtGKt la  +a + ++  +++ 
  EEA19089.1 1033 KDAVMETIQLPLERPELFAKGM-KKRSGILFYGPPGTGKTLLAKAIATEFSL--NFFS 1087
                  5566677888999999999999.89999***************999988775..4555 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.0   0.0   6.1e-05     0.046       4      30 ..    1056    1082 ..    1052    1115 .. 0.76
   2 ?   -2.4   0.0         7   5.2e+03      81     105 ..    1107    1132 ..    1098    1176 .. 0.63

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 6.1e-05
      AAA_22    4 tagilvvtGesGtGKTtllrrlleqld 30  
                  +++ ++ +G++GtGKT+l++ ++ ++ 
  EEA19089.1 1056 KRSGILFYGPPGTGKTLLAKAIATEFS 1082
                  6777899**************999884 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 7
      AAA_22   81 aleqalraravielliiDEaqhlr..s 105 
                  ++ q +r+++   ++  DE + +   +
  EEA19089.1 1107 RVFQRARDARP-CVVFFDELDSVApkR 1132
                  33344444444.899999999986541 PP

>> TIP49  TIP49 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   1.6e-05     0.012      52      99 ..    1059    1104 ..    1049    1116 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 1.6e-05
                  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49   52 avLlaGpsgtGktalaiaiskelgedvpfvalsgsevyslevkktevl 99  
                  ++L+ Gp+gtGkt la ai+ e++  + f +++g e+  + +  +e+ 
  EEA19089.1 1059 GILFYGPPGTGKTLLAKAIATEFS--LNFFSVKGPELLNMYIGESEAN 1104
                  79********************98..99********999999888874 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   2.5e-05     0.019      45      70 ..    1055    1080 ..    1050    1113 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 2.5e-05
   IstB_IS21   45 ekkenivllGpsGvGKshlaialgve 70  
                  +k+ +i++ Gp+G+GK+ la a+++e
  EEA19089.1 1055 KKRSGILFYGPPGTGKTLLAKAIATE 1080
                  67899*****************9986 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0       5.2   3.9e+03      10      39 ..     798     841 ..     797     877 .. 0.74
   2 ?   12.9   0.0   0.00016      0.12       1      25 [.    1060    1102 ..    1060    1173 .. 0.62

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 5.2
      AAA_18  10 GKttlakeLskrlgf..............gvnlrdvakenglll 39 
                 GKttla +   + g+              g n +dv +e ++  
  EEA19089.1 798 GKTTLASRACAEIGLhaftidaydiltegGANGGDVKTEAYMKA 841
                 9****999966655566766666666666666666666666654 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 0.00016
      AAA_18    1 IlltGtpGvGKttlakeLskrlgf..................g 25  
                  Il  G+pG+GKt lak+++ +  +                   
  EEA19089.1 1060 ILFYGPPGTGKTLLAKAIATEFSLnffsvkgpellnmyigesE 1102
                  8999**************9986223333333333333333331 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.1   6.8e-05     0.051      25      43 ..    1060    1078 ..    1048    1083 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 6.8e-05
  Mg_chelatase   25 lllvGppGsGKtmlakrlp 43  
                    +l++GppG+GKt+lak+++
    EEA19089.1 1060 ILFYGPPGTGKTLLAKAIA 1078
                    89**************986 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0       2.1   1.6e+03      30      49 ..     797     816 ..     771     825 .. 0.77
   2 ?   12.0   0.0   0.00022      0.16      14      51 ..    1054    1091 ..    1038    1105 .. 0.79

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 2.1
                 SSHHHHHHHHHHHTT----- CS
        TsaE  30 aGKTtlvrglakalgveevk 49 
                  GKTtl+   ++++g+++ +
  EEA19089.1 797 IGKTTLASRACAEIGLHAFT 816
                 7*******999999987544 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 0.00022
                  HHHCHTEEEEEEESTTSSHHHHHHHHHHHTT--..----T CS
        TsaE   14 lakalgdvilLeGdLGaGKTtlvrglakalgve..evkSP 51  
                  ++k  ++ il++G+ G+GKT l++++a ++ ++  +vk P
  EEA19089.1 1054 MKK--RSGILFYGPPGTGKTLLAKAIATEFSLNffSVKGP 1091
                  333..4569*********************9988889888 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   0.00017      0.13       2      33 ..    1060    1091 ..    1059    1132 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00017
                  EEEE--SSSSHHHHHHHGGGGBS--EEEEE-- CS
       AAA_5    2 vlLvGppGtgKselaerlaaalnreveyvqlt 33  
                  +l  GppGtgK+ la+ +a  +  +++ v ++
  EEA19089.1 1060 ILFYGPPGTGKTLLAKAIATEFSLNFFSVKGP 1091
                  7899**************99988888877665 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00011     0.082      10      38 ..    1048    1076 ..    1045    1108 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00011
      ATPase   10 eilkgGipegrvvlitGepGtGKtifalq 38  
                  e++  G+ +++ +l +G pGtGKt++a+ 
  EEA19089.1 1048 ELFAKGMKKRSGILFYGPPGTGKTLLAKA 1076
                  68899*********************975 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   0.00012     0.087      26      58 ..    1050    1082 ..    1042    1130 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00012
       AAA_7   26 lelllknkkpvllvGptGtGKtviikdllkkld 58  
                  + + +k++  +l++Gp GtGKt+++k + ++++
  EEA19089.1 1050 FAKGMKKRSGILFYGPPGTGKTLLAKAIATEFS 1082
                  566789999****************99888776 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0      0.44   3.3e+02      11      27 ..     795     811 ..     788     888 .. 0.75
   2 ?    8.6   0.0    0.0025       1.9       6      76 ..    1061    1128 ..    1056    1152 .. 0.73

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.44
      AAA_14  11 RrvGKTtllkqlikell 27 
                 R++GKTtl+ +   e  
  EEA19089.1 795 RHIGKTTLASRACAEIG 811
                 99******988776654 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.0025
      AAA_14    6 vitGaRrvGKTtllkqlikellvkkesilyinldderdkk..ladpekllelileklkeekktylflDEiqev 76  
                  +  G+  +GKT l+k ++ e         +++++ +++ +  + ++e + + +++++++ +  ++f+DE   v
  EEA19089.1 1061 LFYGPPGTGKTLLAKAIATEFS-----LNFFSVKGPELLNmyIGESEANVRRVFQRARDARPCVVFFDELDSV 1128
                  6689999******999997766.....5556666655544114455545555555555568999*****8765 PP

>> PhoH  PhoH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00028      0.21      13      43 ..    1051    1081 ..    1042    1089 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00028
                  HHHHHH-SEEEEE--TTSSTTHHHHHHHHHH CS
        PhoH   13 lealkkndivfaiGpaGtGKtylavalavea 43  
                  ++ +kk + +   Gp GtGKt+la a+a e 
  EEA19089.1 1051 AKGMKKRSGILFYGPPGTGKTLLAKAIATEF 1081
                  5567777778889*************99875 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00042      0.31       2      39 ..    1060    1102 ..    1059    1118 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00042
      AAA_28    2 ivitGgestGKTtlleaLaar...gypvv..pEaareileekl 39  
                  i + G+++tGKT l++a+a +   ++  v  pE   +++ e  
  EEA19089.1 1060 ILFYGPPGTGKTLLAKAIATEfslNFFSVkgPELLNMYIGESE 1102
                  7899***************776664444447888877776655 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0      0.63   4.7e+02      12      28 ..     796     816 ..     787     871 .. 0.79
   2 ?    9.1   0.1    0.0013      0.96       5      22 ..    1060    1077 ..    1056    1092 .. 0.84

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.63
      AAA_24  12 giGKTtlakel....gpkplf 28 
                  iGKTtla+++    g +++ 
  EEA19089.1 796 HIGKTTLASRAcaeiGLHAFT 816
                 79*******996666444444 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.0013
      AAA_24    5 iliyGpsgiGKTtlakel 22  
                  il yGp+g+GKT lak +
  EEA19089.1 1060 ILFYGPPGTGKTLLAKAI 1077
                  789************987 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0       6.7     5e+03      31      42 ..     797     808 ..     797     813 .. 0.84
   2 ?    6.9   0.0    0.0041       3.1      20      44 ..    1057    1081 ..    1047    1085 .. 0.80
   3 ?    1.2   0.0      0.24   1.8e+02      49      81 ..    1186    1219 ..    1179    1228 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 6.7
                 SSHHHHHHHHCC CS
      NB-ARC  31 vGKttlakqiln 42 
                 +GKttla+ +  
  EEA19089.1 797 IGKTTLASRACA 808
                 6******99876 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0041
                  SEEEEEEESTTSSHHHHHHHHCCSH CS
      NB-ARC   20 slvvalvGmgGvGKttlakqilnks 44  
                  +  + ++G +G GKt lak i  ++
  EEA19089.1 1057 RSGILFYGPPGTGKTLLAKAIATEF 1081
                  455889**************99886 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.24
                  CCBTEEEEEEEESX.XHHHHHHHXXHHHHHCCCT CS
      NB-ARC   49 grFdsvawvvvskt.dkseeiletilkeLslsed 81  
                  grFd ++++ +s+t dk+ +ile++ +++ ls d
  EEA19089.1 1186 GRFDKMIYLGISDThDKQTKILEALTRKFTLSPD 1219
                  69**********98356789*****999988865 PP

>> MAGE_N  Melanoma associated antigen family N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   2.1    0.0021       1.5       6      73 ..     301     381 ..     299     392 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.0021
      MAGE_N   6 rarEkrrqaraetqglegaQataaeeee.............stssssplsedtpesspaagtpsapqspqgapssttaaaa 73 
                 ra E+   + a  q ++ a+  a e e              st+s + +s d++ ++ +  +p+ pq+p g++s+ ++++ 
  EEA19089.1 301 RAVEEEADDTANEQFFSAAEDRALETEMesttppddsetdvSTASDHDSSDDSLDDMISLAAPQLPQQPSGVMSAMSSMTP 381
                 677788888888899999888887666578999999999999999999999999999966699********9999998874 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1452 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       521  (0.0290591); expected 358.6 (0.02)
Passed bias filter:                      441  (0.024597); expected 358.6 (0.02)
Passed Vit filter:                        71  (0.00396006); expected 17.9 (0.001)
Passed Fwd filter:                        24  (0.00133861); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              24  [number of targets reported over threshold]
# CPU time: 0.99u 0.31s 00:00:01.30 Elapsed: 00:00:00.49
# Mc/sec: 8865.49
//
Query:       EEA19090.1  [L=575]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.7e-33  114.1  57.6    3.7e-31  108.3  57.3    2.7  2  MFS_1     Major Facilitator Superfamily
    8.1e-23   80.7  20.4      1e-22   80.3  20.4    1.1  1  TRI12     Fungal trichothecene efflux pump (TRI12)
    2.2e-14   53.2   2.6    2.2e-14   53.2   2.6    2.3  2  Sugar_tr  Sugar (and other) transporter
  ------ inclusion threshold ------
        2.2    6.4  15.1       0.18   10.1   5.6    3.0  3  OATP      Organic Anion Transporter Polypeptide (OATP) family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  108.3  57.3   8.3e-35   3.7e-31       2     352 ..      74     473 ..      73     474 .. 0.86
   2 ?   -1.4   0.0       0.2   8.8e+02     150     175 ..     537     559 ..     531     571 .. 0.74

  Alignments for each domain:
  == domain 1  score: 108.3 bits;  conditional E-value: 8.3e-35
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfasslwlllvlrvlqGlga 99 
                 + ++f+   ++++lg+alp +++ dl+ s  +  ++  +y+l  +v +++++++s+ fGr++ l +++ lf++g +++++ a+++ +++v+rvlqGlg+
  EEA19090.1  74 AASLFVFQVDATCLGIALP-TISGDLHGSSLQSFWASLAYTLCGLVIQPIWASISNTFGRKPPLYTSMGLFFIGsIVFAT-AQNMNTIIVGRVLQGLGG 170
                 66899999***********.*******99999999***************************************333333.48888************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 g++  ++ +++ad+++ eer+ ++gl+++ +++G i+gp +g+l++ +++Wr+v +++ +++ +++ l +++l  +p++        ++          
  EEA19090.1 171 GGIDVLAEVILADMTTLEERSTYLGLMAIPSAVGNIMGPTVGALFSNYASWRWVGWFNLFFLGIGAPLLFFFLKLRPVPLDATLAGNLKrvdwigivlv 269
                 *****************************************************************99766666666666666666666679******** PP

       MFS_1 189 ..........................................kgtgpaplvpawkallkdpvlw.illialllfffgfsglltllplylqevlgls... 241
                                                           + +   p++p  ++++++     + l++ ++ ++++ +ll++lpl+  +   l    
  EEA19090.1 270 vigvtafvvplswagslypwaawqtlvpmligvavifvfvfyEAKPTEPIIP-HRLFHSKT--GnMTLLGGFIHGIILVSLLQYLPLL-YQAVELEtai 364
                 ***************9999999999999999999999999988888888888.44444444..35699999999999999*******5.8888888656 PP

       MFS_1 242 ....glllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllllvlvliGfglgfv..fpsllalasdlappeea 334
                     +ll +++++ ++a+v++ + +l+g ++      + l ++ ++l+l++ +lall+v ss+++ + +++l+G g+++   + + + + ++++  + +
  EEA19090.1 365 ssavSLLPTSIISVVFAAVAMLMVPLFGGYV------WLLRFSWVILTLGTGILALLNVGSSSSMRYGLSILWGSGVALLrlNLLPMQASVKNV--DDT 455
                 6656556666666666666655555555544......69*****************************************55555555666666..*** PP

       MFS_1 335 gtasglfntagslggalg 352
                 g a++ f +++ +gg++g
  EEA19090.1 456 GLAIAQFLSIRMFGGLVG 473
                 ***************998 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.2
       MFS_1 150 Wravfyilaivsllafvlfllllpee 175
                 ++ +fy ++++s l+++    l++ +
  EEA19090.1 537 FQIIFYTMTGLSGLGLI---TLVFLD 559
                 67899999999999977...333333 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.3  20.4   2.3e-26     1e-22       6     466 ..      19     486 ..      14     504 .. 0.76

  Alignments for each domain:
  == domain 1  score: 80.3 bits;  conditional E-value: 2.3e-26
       TRI12   6 hekgldlesqp...ddrlrakalatsa..delpegyyrsprvva..sfaafslnvvatyfvlqasas....alpnilqdvgqsensslfstl.wttgqa 92 
                   +gld+e +p   dd  +a+ +a     +e  +   + p+     sf    + ++a+ fv+q  a+    alp i  d+  s  +s++++l +t+   
  EEA19090.1  19 TPDGLDIEYNPktvDDTEKAQKVAERQapEEQLDVGSTEPKTKKslSFKLAFIGLAASLFVFQVDATclgiALPTISGDLHGSSLQSFWASLaYTLCGL 117
                 55799999988666899999999864312566677778888766115556667889*******99974445789******9999999988774788888 PP

       TRI12  93 vsilvmgrltdrfgrrpfvilthilglvgaivgctatkfntllaamtllgvaagpaga.splfvgel..msnktkflgllivsipvvvtsglspylgqr 188
                 v   +   +++ fgr+p +  +  l ++g+iv +ta+++nt++    l g+  g     + +++ ++  + +++ +lgl+  +ip  v + ++p +g  
  EEA19090.1 118 VIQPIWASISNTFGRKPPLYTSMGLFFIGSIVFATAQNMNTIIVGRVLQGLGGGGIDVlAEVILADMttLEERSTYLGLM--AIPSAVGNIMGPTVGAL 214
                 888899***************999***************************99987761455556651245677888886..689999999******** PP

       TRI12 189 laiqgswrwifyiyiitsaiavllivvwyyppsfaqlhgkkvrkreelakldwigiilvivgvslfllgvswggkpnspwnsakviglissglgslvvf 287
                 ++   swrw+ +  +    i   l+  +      + +    ++   +l ++dwigi+lv++gv+ f++ +sw g    pw + + +  +  g+  + vf
  EEA19090.1 215 FSNYASWRWVGWFNLFFLGIGAPLLFFFLKL---RPV-PLDATLAGNLKRVDWIGIVLVVIGVTAFVVPLSWAGSL-YPWAAWQTLVPMLIGVAVIFVF 308
                 **********999998888887776554432...211.23455667899*************************75.7****999999999******** PP

       TRI12 288 alyevygkpvrpivppalfkdtrgfvcil...lissimgamnlslviiypqqvvnifgsslknweetawmsatasfgtgagvvvlgslfhlvrhirwqi 383
                  +ye   kp +pi+p  lf+   g + +l   +   i+ ++   l ++y    ++   ss      t+ +s   +  ++  v ++g  + l+r   w i
  EEA19090.1 309 VFYE--AKPTEPIIPHRLFHSKTGNMTLLggfIHGIILVSLLQYLPLLYQAVELETAISSAVSLLPTSIISVVFAAVAMLMVPLFGGYVWLLRF-SWVI 404
                 ***9..5***************999887655244455666666777888777788888888888899988877666666666678888888885.6888 PP

       TRI12 384 lvgalwltaflgamssvnrdnknaaialsvlsgfvvawaqditmllvqfittdedlgvafavvaaarpfag....siftaafislys 466
                 l     + a+l   ss           ls+l g  va  +   + +   +   +d g+a+a   + r f g    +i +a f s++s
  EEA19090.1 405 LTLGTGILALLNVGSSSS-----MRYGLSILWGSGVALLRLNLLPMQASVKNVDDTGLAIAQFLSIRMFGGlvglTISSAIFNSVFS 486
                 876666666666555432.....3456888888888877655555666677777888888888888877763333345566666665 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.2   2.6   4.9e-18   2.2e-14      43     185 ..      91     241 ..      30     247 .. 0.80
   2 ?   -2.9   1.8      0.52   2.3e+03      80     117 ..     375     410 ..     330     430 .. 0.58

  Alignments for each domain:
  == domain 1  score: 53.2 bits;  conditional E-value: 4.9e-18
                 H............HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS- CS
    Sugar_tr  43 e.........ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiAp 132
                           ss++s +   ++ + +++ + +   ++++fGRk+ l ++  lf+ig+++ a+a+   ++  +ivgRvl G+g G++ vl+ + ++ +++
  EEA19090.1  91 LptisgdlhgSSLQSFWASLAYTLCGLVIQPIWASISNTFGRKPPLYTSMGLFFIGSIVFATAQ---NMNTIIVGRVLQGLGGGGIDVLAEVILADMTT 186
                 04444566668888889989999999999999999*****************************...9******************************* PP

                 SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-..TTHHHHHHHCCHHHHHHHH CS
    Sugar_tr 133 kklRgalvslyqlaitfGilvaaifglglnktsn..adgwrillglqlvpallll 185
                  + R++  +l     ++G +++ ++g+ ++++ +   +gw  l++l +  +ll++
  EEA19090.1 187 LEERSTYLGLMAIPSAVGNIMGPTVGALFSNYASwrWVGWFNLFFLGIGAPLLFF 241
                 *****************************99999444455555555555554444 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.52
                 HHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHH CS
    Sugar_tr  80 liaavlfvigavlqaaakgknsvevlivgRvlvGigvG 117
                 +i++v++ ++ ++  +      v++l ++ v++ +g G
  EEA19090.1 375 IISVVFAAVAMLMVPLFG--GYVWLLRFSWVILTLGTG 410
                 222222222222222222..234444444444444444 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   5.6   3.9e-05      0.18     133     229 ..     157     241 ..     139     247 .. 0.87
   2 ?    0.8   0.2     0.025   1.1e+02      60      83 ..     255     278 ..     252     285 .. 0.88
   3 ?   -0.4   0.1     0.058   2.6e+02     165     196 ..     454     485 ..     445     499 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 3.9e-05
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 133 llfflaqlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllklyvdidseisltpkdprWvgaWWlgflilgvlllla 229
                   ++++ +l+G+G+  i  l+   + D ++ ++ ++ylg++   +++G ++G ++G+l+ + y  +           rWvg + l fl +g+ ll++
  EEA19090.1 157 NTIIVGRVLQGLGGGGIDVLAEVILADMTTLEERSTYLGLMAIPSAVGNIMGPTVGALFSN-YASW-----------RWVGWFNLFFLGIGAPLLFF 241
                 4799*****************************************************9988.8777...........78887777777777666655 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.025
                 xxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP  60 ggrghrPrwigigallmalgslll 83 
                 +g+ +r  wigi ++++++ ++++
  EEA19090.1 255 AGNLKRVDWIGIVLVVIGVTAFVV 278
                 68899**************99987 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 0.058
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 165 nsplylgilyalrilGpalGfllGslllklyv 196
                 ++ l ++ + ++r++G  +G +++s++ +  +
  EEA19090.1 454 DTGLAIAQFLSIRMFGGLVGLTISSAIFNSVF 485
                 5778999999***********99998766444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (575 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       745  (0.0415528); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.72u 0.31s 00:00:01.03 Elapsed: 00:00:00.50
# Mc/sec: 3445.83
//
Query:       EEA19091.1  [L=434]
Description: C2H2 transcription factor (Ace1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    0.00015   22.1  19.7    0.00055   20.3   5.1    3.2  3  zf-C2H2      Zinc finger, C2H2 type
     0.0012   18.5   0.2     0.0012   18.5   0.2    2.8  2  zf-H2C2_5    C2H2-type zinc-finger domain
     0.0055   17.4   4.4     0.0055   17.4   4.4    3.6  3  zf-C2H2_4    C2H2-type zinc finger
  ------ inclusion threshold ------
       0.35   11.2   8.1       0.82   10.0   5.4    2.6  2  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
       0.63   10.1   6.0        3.1    7.9   0.5    2.7  2  zf-BED       BED zinc finger


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   5.1   1.5e-07   0.00055       2      23 .]     155     176 ..     154     176 .. 0.98
   2 ?   -2.0   0.6       1.8   6.6e+03       2       8 ..     181     189 ..     180     190 .. 0.82
   3 !   12.0   0.9   6.5e-05      0.23       6      23 .]     222     240 ..     215     240 .. 0.90

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 1.5e-07
                 EETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   2 kCpdCgksFkrksnLkrHirtH 23 
                 kC++C+k+Fkr+ ++++H +tH
  EEA19091.1 155 KCSYCDKVFKRPCDFTKHEKTH 176
                 8********************9 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.8
                 EET..TTTE CS
     zf-C2H2   2 kCp..dCgk 8  
                 kCp  dC++
  EEA19091.1 181 KCPveDCKY 189
                 899999975 PP

  == domain 3  score: 12.0 bits;  conditional E-value: 6.5e-05
                 TTEEESSHHHHHHHHHC.C CS
     zf-C2H2   6 CgksFkrksnLkrHirt.H 23 
                 C+++ kr snLk+H+ + H
  EEA19091.1 222 CTYTSKRESNLKQHMEKaH 240
                 ***************9999 PP

>> zf-H2C2_5  C2H2-type zinc-finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   5.7     0.062   2.2e+02       2      25 ..     155     177 ..     155     178 .. 0.84
   2 !   18.5   0.2   3.4e-07    0.0012       6      24 ..     222     240 ..     220     241 .. 0.93

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.062
   zf-H2C2_5   2 KCsqCDYstawksnLkRHlrrkHt 25 
                 KCs+CD + +++++ ++H + +H+
  EEA19091.1 155 KCSYCDKVFKRPCDFTKHEK-THS 177
                 9*****88888888888888.886 PP

  == domain 2  score: 18.5 bits;  conditional E-value: 3.4e-07
   zf-H2C2_5   6 CDYstawksnLkRHlrrkH 24 
                 C Y++++ snLk+H+++ H
  EEA19091.1 222 CTYTSKRESNLKQHMEKAH 240
                 99**************888 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   4.4   1.5e-06    0.0055       2      23 ..     155     176 ..     154     177 .. 0.95
   2 ?   -1.0   0.7       1.3   4.8e+03       3      24 .]     187     208 ..     180     208 .. 0.68
   3 !    7.7   0.7    0.0021       7.6       1      24 []     215     240 ..     215     240 .. 0.77

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 1.5e-06
   zf-C2H2_4   2 kCpiCgksFsskkaLlrHlkth 23 
                 kC++C+k+F++++++ +H kth
  EEA19091.1 155 KCSYCDKVFKRPCDFTKHEKTH 176
                 8********************* PP

  == domain 2  score: -1.0 bits;  conditional E-value: 1.3
   zf-C2H2_4   3 CpiCgksFsskkaLlrHlkthH 24 
                 C++ +  +++ k+  rH++  H
  EEA19091.1 187 CKYHHVGWPTEKERDRHVNDRH 208
                 6666777777777666877665 PP

  == domain 3  score: 7.7 bits;  conditional E-value: 0.0021
   zf-C2H2_4   1 fkCpi..CgksFsskka..LlrHlkthH 24 
                 + C +  C  +++sk++  L++H+++ H
  EEA19091.1 215 YNCMFnpC--TYTSKREsnLKQHMEKAH 240
                 66778889..776666677******988 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   5.4   0.00023      0.82       4      24 ..     156     176 ..     154     177 .. 0.94
   2 ?    0.5   0.0      0.23   8.3e+02      11      21 ..     226     236 ..     221     237 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00023
                  BTTTTBBBSSHHHHHCCTTSH CS
  zf-C2H2_jaz   4 CvlCdKyFksenaldnHlkSK 24 
                  C +CdK Fk   ++ +H+k++
   EEA19091.1 156 CSYCDKVFKRPCDFTKHEKTH 176
                  *******************98 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.23
                  BSSHHHHHCCT CS
  zf-C2H2_jaz  11 FksenaldnHl 21 
                   k e++l++H+
   EEA19091.1 226 SKRESNLKQHM 236
                  5899******7 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.7     0.013        47      18      29 ..     155     166 ..     150     176 .. 0.80
   2 ?    7.9   0.5   0.00088       3.1      25      43 ..     223     240 ..     215     241 .. 0.75

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.013
                 EETTTTEE---- CS
      zf-BED  18 vCryCgkilsrg 29 
                 +C yC k+++r 
  EEA19091.1 155 KCSYCDKVFKRP 166
                 8********995 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.00088
                 E----SSTHHHHHHHHHS- CS
      zf-BED  25 ilsrgggttnLkrHLrrkH 43 
                 +++++   +nLk+H++++H
  EEA19091.1 223 TYTSK-RESNLKQHMEKAH 240
                 44554.559*********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (434 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       597  (0.033298); expected 358.6 (0.02)
Passed bias filter:                      317  (0.0176809); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.49u 0.24s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 3129.09
//
Query:       EEA19092.1  [L=552]
Description: amino acid permease family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.9e-55  186.8  43.7    7.2e-55  186.5  43.7    1.0  1  AA_permease_2  Amino acid permease
    6.3e-23   81.1  35.2    8.6e-23   80.7  35.2    1.1  1  AA_permease    Amino acid permease
  ------ inclusion threshold ------
        0.3   11.3   2.9       0.29   11.3   0.4    2.4  2  DUF3493        Low psii accumulation1 / Rep27


Domain annotation for each model (and alignments):
>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  186.5  43.7   1.2e-58   7.2e-55       1     424 [.      42     497 ..      42     500 .. 0.82

  Alignments for each domain:
  == domain 1  score: 186.5 bits;  conditional E-value: 1.2e-58
  AA_permease_2   1 lsllsafalvigsvigsgifvkn....laasggpalilwvwiavligslavllvyaElssalprsgGiyvytkaaf.....gkkvaflsawfnwfa 87 
                    ++ +s +al++ ++    ++++     ++++ggp++ilw++  v ++ l+v+  + El+s +p+  G+  ++++++     g+++ +++aw+n+f+
     EEA19092.1  42 FDIWSMLALAFCVLGT-WSTFAQdlasGLTNGGPVSILWGLCLVTACNLCVAVSLGELCSSMPTALGQAYWVHRLWeqkrfGRFASYMCAWINTFG 136
                    5678889999987644.44444447778889***************************666**************87777799999********** PP

  AA_permease_2  88 yvpvlasilsvaasyllnalgpdlqgn.......twltyliaiaililvalinirgike...sakiqnilgilkillpliiliilglitvdgggfs 173
                    ++  +as +  +++++l++ +  ++ n        w ++l++i+i+i++++in+++ ++   + +++ ++g++   ++++++ ++ li+v+ +  +
     EEA19092.1 137 WWTLTASQIGFMTNFMLGM-KIMFD-NewagaseGWVQFLVYIGITIVITIINLVACRKdkfLPYFNDFVGVWFC-GLFVVFSLALLIAVGTK--P 227
                    ***9988777777777775.33222.223555669******************9999873336889999999999.67788887888887442..2 PP

  AA_permease_2 174 sl......stetdtffpngwp.gv..llgllivlwsfdGfesaanvsee..vkkkdvpkaifigllivlvlyllvniaflgvvpd.deianlsnlg 257
                    +l         +++++++gw+ gv  + gl ++++ +++f+s+++++ee  ++++++p+ai ++++  +++++ ++++ l++++d d i n+++ +
     EEA19092.1 228 DLsfqpasFVFGKWINQTGWSdGVtwFIGLVQAAYGLTAFDSVIHMVEEipAPRRNAPRAIYLAVACGAISGFIFMLVCLFCIQDvDAIINSATGL 323
                    2223446544445688889997656699*********************5555699*****************************66676666644 PP

  AA_permease_2 258 svaalffeavggkvvaiivvilialsllgaintavigssrvlealardgvlP..rffakvn.kfgspiraiiltaivslillllfllassaaynfl 350
                     ++ l+ +a g   + +++++l+++  lg   +  +++sr+ + +ard + P   +fa v+ k++ p ra++l+  ++ ++++l+l+a ++ ++++
     EEA19092.1 324 PFMDLVQNAIG-LRGGVALIALFVFNGLGQSVSIATTASRLTWGFARDSGVPfsGYFACVDqKWKVPARALWLQGALVGLVGILYLFA-NTVLDAI 417
                    45666666666.4555566668888999***********************************************************9.7****** PP

  AA_permease_2 351 lsvsslgliisyllliigal.ilrkkrphlkrpgk.....ilvaiigalfllfllvalffppkgpatqssliytiiltva 424
                    lsvs+++l isy+l+i+++l + r+k p  ++++      ++v+++++++++++ v++ffp+    ++s ++y+i+++++
     EEA19092.1 418 LSVSTIALTISYGLPIFALLvVGRDKLPAGGTFRLgrrvgPIVNWVSVIYCCITTVFFFFPSSPNPAPSDMNYAIAVFGV 497
                    ***************999883455555644443323355589*********************999********998876 PP

>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.7  35.2   1.4e-26   8.6e-23       4     460 ..      51     502 ..      49     515 .. 0.74

  Alignments for each domain:
  == domain 1  score: 80.7 bits;  conditional E-value: 1.4e-26
  AA_permease   4 vialggviGtglfvglgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgp.elGfviGlnylfswitvlaleltaasil 100
                   ++++g ++t     l++ l ++Gp+++l ++ l++++ ++v++slge+ + +p + g +++++r +++ ++G + +++    wi +++  + +as +
   EEA19092.1  51 AFCVLGTWSTF-AQDLASGLTNGGPVSILWGLCLVTACNLCVAVSLGELCSSMPTALGQAYWVHRLWEQkRFGRFASYM--CAWINTFGWWTLTASQI 145
                  57788888874.568999*************************************************988999999988..66666666665555554 PP

  AA_permease 101 iqfwelvtdlpkawvt.............gavflvvlliinlvgvkvygeaefi..lalikiiaiiafiivg.iillaggkpnkgagfrflgdngsif 182
                    + +++  +   +++              +v +++ ++i+++++ + ++  f+  ++ ++++ + ++++v+   ll+  +++++    +++ +++  
   EEA19092.1 146 GFMTNFMLGMK--IMFdnewagasegwvqFLVYIGITIVITIINLVACRKDKFLpyFNDFVGVWFCGLFVVFsLALLIAVGTKPD---LSFQPASF-- 236
                  44444444444..233445577777778856666665555556665666656655566666666666666664444444444444...23333333.. PP

  AA_permease 183 knnlppgfa.keeegafknfisvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasaaspfvif 279
                     ++++++ + + +    +++++v+++ ++t + +v+ + +E+  P+++ P+ai  +v   +i+  +++l++ +++++ d  ++n sa++++ + ++
   EEA19092.1 237 ---VFGKWInQTGWSDGVTWFIGLVQAAYGLTAFDSVIHMVEEIPAPRRNAPRAIYLAVACGAISGFIFMLVCLFCIQDVD-AIIN-SATGLPFMDLV 329
                  ...33333333344445679**********************************************************999.4555.466678999** PP

  AA_permease 280 ikesgvsvlaplinaviltaalssansslysasRvlyslakdglaP...kvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisal 374
                  ++  g+++   li+++++ + l+ ++s+ ++asR+ + +a+d   P    ++ + +k++vP+ra+ l     +l+ l+  l+l a +v + +l++s++
   EEA19092.1 330 QNAIGLRGGVALIALFVF-NGLGQSVSIATTASRLTWGFARDSGVPfsgYFACVDQKWKVPARALWLQG---ALVGLVGILYLFANTVLDAILSVSTI 423
                  ****************99.5689999**********************88888999********97654...444444445555559*********** PP

  AA_permease 375 iglivwlliilsylrfRkalkyqgrsieelgfkaallplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfl 460
                  +  i ++l i+++l++ + +   g     ++   +++p   ++ ++ ++i +++ ++  +      p+ ++  + +a++  +l++ 
   EEA19092.1 424 ALTISYGLPIFALLVVGRDKLPAGG---TFRLGRRVGPIVNWVSVIYCCITTVFFFFPSSPN----PAPSDMNYAIAVFGVMLVIA 502
                  ********99999977555555555...48999************99999888766664433....33334444444433222222 PP

>> DUF3493  Low psii accumulation1 / Rep27
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.4   4.9e-05      0.29       7      42 ..     273     308 ..     269     349 .. 0.75
   2 ?   -3.2   0.1       1.6   9.7e+03      61      76 ..     393     408 ..     386     414 .. 0.60

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 4.9e-05
     DUF3493   7 LraEakaPfRglRlflYlafaaSaliGalifllrll 42 
                 + +E+ aP R+  +++Yla+a +a  G++++l+ l+
  EEA19092.1 273 MVEEIPAPRRNAPRAIYLAVACGAISGFIFMLVCLF 308
                 679****************98877777777665544 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 1.6
     DUF3493  61 laiqvgavalfvfLlr 76 
                 l +q + v l+++L+ 
  EEA19092.1 393 LWLQGALVGLVGILYL 408
                 4455555555555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (552 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       675  (0.0376485); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.75u 0.40s 00:00:01.14 Elapsed: 00:00:00.59
# Mc/sec: 2832.56
//
Query:       EEA19093.1  [L=703]
Description: peroxisomal copper amine oxidase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   9.6e-154  512.2   0.0   1.1e-153  512.0   0.0    1.1  1  Cu_amine_oxid    Copper amine oxidase, enzyme domain
    6.5e-18   65.0   0.0    1.6e-17   63.7   0.0    1.7  1  Cu_amine_oxidN3  Copper amine oxidase, N3 domain
      4e-08   33.4   0.0    7.5e-08   32.5   0.0    1.5  1  Cu_amine_oxidN2  Copper amine oxidase, N2 domain


Domain annotation for each model (and alignments):
>> Cu_amine_oxid  Copper amine oxidase, enzyme domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  512.0   0.0  1.9e-157  1.1e-153       1     410 []     251     671 ..     251     671 .. 0.97

  Alignments for each domain:
  == domain 1  score: 512.0 bits;  conditional E-value: 1.9e-157
                    .----TT---SEEETTTEEEETTEEEEEEEETTTEEEEEEEEETT......EEEEEEEEEEEEEEEE--SSHHHHH-EEEGGGT.-SGGG-----T CS
  Cu_amine_oxid   1 levvqpeGpsfkvdegnlvewqkWsfrvgfnrreGlvlhdvrykg......rrilyrlslsemvvpYgdprppasrkaafDlgeyglGklansLel 90 
                    ++++qp+G+sf++ +gn+++w+++++++gfn+reG+v++dvr+++      r+++ r+s+ emvvpYg+p++p+++k+afD+geyg G ++nsL+l
     EEA19093.1 251 INITQPQGVSFRM-RGNELSWAGYKMHIGFNYREGIVISDVRIDDpyqereRTLFNRISVVEMVVPYGSPDTPHHKKHAFDVGEYGSGLMTNSLKL 345
                    689**********.8***********************************9********************************************* PP

                    TTSS-TT-EEEEEEEEE..TEEEEEEEEEEEEEEE-S-SEEEE-S....EEEE--EEEEEEEEEEETTEEEEEEEEE-TTS-EEEEEEEEE----E CS
  Cu_amine_oxid  91 gcDClgeityldavladssgepvtiknaiCifEedagilwkHtdfrtgraevtrnreLvvrtiatvgNYdYifdyiFkqdGsievevratGilsta 186
                    gcDC+g i+ylda++++ +ge+  iknaiCi+Eed+g+l+kHtd+r+g+++++r+r+L++++i+t +NY+Y f+++F++dG+ ++ev++tG l+t+
     EEA19093.1 346 GCDCKGAIHYLDAIVSTGKGEAAMIKNAICIHEEDNGLLFKHTDYRDGTVVSARDRKLIISQIITAANYEYGFYHTFTLDGTYKLEVKLTGQLNTY 441
                    ************************************************************************************************ PP

                    E-T......GG--EEETTEE---EEEEEEEEEEE-T.SSEEEEEEEEE-T...TT.T-...-EEEEEEEEEE--BGGG-EE--.-GG-EEEEEEEE CS
  Cu_amine_oxid 187 alaeeee.skygtrvapgvlasiHqHlfslrvDldidgeknsvveeelvp.eepelgeenpagnafkvektvletekeaaldldpeknrvlkivne 280
                    +++++e+ +++gt+v p+++a++HqH+fslrvD++idg++nsv+++++ p eep  +++n +gn+f+++kt+l+t+ e+a ++ +e++r ++ivn+
     EEA19093.1 442 PMHPTEQaAPWGTEVGPRINAQNHQHIFSLRVDPEIDGTNNSVIQSDALPsEEPVGSPNNYYGNGFYAKKTPLRTALEGAAEYCHETSRSWDIVNP 537
                    ****99658***************************************9987788888************************************** PP

                    EEE-.TTS-EEEEEEE-S----..---SS-TTTTTTTGGGG-SEEEEE--TT---S--TTGG-TTS......---GGGG-.S--B-SSEEEEEEEE CS
  Cu_amine_oxid 281 nkkn.klgepvgYklvpssaasqlllakesslvakraefakhhlwvtkykdselyaageynnqskg.....epvglakwvednesieneDlVvWvt 370
                    n  n ++ +pvgYk+++  ++++lll+k++s+v+kra fa+++lwv++ykd el++ag+y+ qs+g     +++++ +w+++nesien+D+V++++
     EEA19093.1 538 NIINeICHKPVGYKILN--NNCPLLLPKPGSVVWKRAGFARKALWVVPYKDYELFPAGDYVCQSDGrdnhpDNQTVVDWANRNESIENTDIVCYLQ 631
                    *****************..55999***************************************99988754339********************** PP

                    EEEEE---GGGSS-TTTSEEEEEEEEES-SSS-GGGG-S- CS
  Cu_amine_oxid 371 lGltHvpraeDfPvmpvetvsflLkPvnFfdenpaldvpp 410
                    +GltH+pr+eD+P+mp+e vs++L+ +nFf++np l vpp
     EEA19093.1 632 FGLTHFPRVEDYPIMPAEPVSIMLRASNFFEKNPGLWVPP 671
                    ************************************9985 PP

>> Cu_amine_oxidN3  Copper amine oxidase, N3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.7   0.0   2.7e-21   1.6e-17       1      95 [.     125     219 ..     125     223 .. 0.96

  Alignments for each domain:
  == domain 1  score: 63.7 bits;  conditional E-value: 2.7e-21
                      S---HHHHHHHHHHHHTGGGGHHHHHHHHTTT.T---EEEE--SS-SSST.T--EEEEEEEE--SSS.-GCGSEEE.EEEEEE--SSSGGG-EE CS
  Cu_amine_oxidN3   1 ppvlleelaeieevikelpqfkealkkrgienldkvvltpltvgyrgeksegkRllkalvyyrtesa.nlyahPiegLellvDleakkvieitd 93 
                      p ++le+l+++e++ +++p +++a+k+ gi++++kv ++ + +g++++++ ++Rl++ l yyr++   n+yahP++ + ++ D+e+ +++  ++
       EEA19093.1 125 PTLTLEDLDIMERICRKDPRVIQACKEIGITDMSKVFIDGWAIGVDERWGFERRLQQGLAYYRESAFdNQYAHPLD-FSIVADTETEEILSVDI 217
                      6799***********************************************************99988********.*************9999 PP

                      EE CS
  Cu_amine_oxidN3  94 qk 95 
                      + 
       EEA19093.1 218 RT 219
                      87 PP

>> Cu_amine_oxidN2  Copper amine oxidase, N2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.5   0.0   1.3e-11   7.5e-08       1      85 [.      34     118 ..      34     120 .. 0.90

  Alignments for each domain:
  == domain 1  score: 32.5 bits;  conditional E-value: 1.3e-11
                      HHHHHHHHHHHHHCCCCCCCCTCT-TTSEEEEEEEEE---HHHHHHHHHCH---S-EEEEEEEEETSSS..SEEEEEEEEEECCSEE CS
  Cu_amine_oxidN2   1 hpLdaltaaeinkvesilkssaletskknsffeveLeePdKkavlqflekgeppppRkAsvvilfGkqt..kelvvdLatgkllspr 85 
                      hpLd l+  ei  +   +++ a   +k+  f+ ++L+eP K+ + ++++  +p p R+ ++++l+ +     e vv+L+   + +++
       EEA19093.1  34 HPLDQLSIEEIPLAAKLIREFA--SPKQVKFNCITLREPRKAEYAAYRQGLGPRPDRRVFAIVLEVGTAncAEVVVNLTKPTVEEWK 118
                      9*************99999999..999********************7777888**********8766657999*****99999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (703 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       263  (0.014669); expected 358.6 (0.02)
Passed bias filter:                      253  (0.0141112); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.71u 0.32s 00:00:01.03 Elapsed: 00:00:00.55
# Mc/sec: 3831.78
//
Query:       EEA19094.1  [L=500]
Description: aldehyde dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   7.2e-185  614.9   0.0   8.1e-185  614.7   0.0    1.0  1  Aldedh    Aldehyde dehydrogenase family
  ------ inclusion threshold ------
        0.2   11.1   0.0        4.5    6.7   0.0    2.2  2  DUF1487   Protein of unknown function (DUF1487)
       0.81   10.4   2.6         45    5.0   0.1    2.9  3  SVS_QK    Seminal vesicle protein repeat


Domain annotation for each model (and alignments):
>> Aldedh  Aldehyde dehydrogenase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  614.7   0.0  1.4e-188  8.1e-185       1     462 []      28     492 ..      28     492 .. 0.99

  Alignments for each domain:
  == domain 1  score: 614.7 bits;  conditional E-value: 1.4e-188
                 EET-SS.SEEEEEETTTCEEEEEEE-B-HHHHHHHHHHHHHHHH..HHTTS-HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH---HHHHHH.HHHHHHH CS
      Aldedh   1 wveses.etievinPatgeviakvpaataedvdaavaaAkeafk..awaklpaeeRaeiLrkaadlleerkeelaeletletGkplaeara.eveeaid 95 
                 wv+s++ ++i++inP+++++i +v+aa+++d+d+avaaA++a    +w++lpa++R+++L+k+ad++ee++  la++et+++Gkp++ ar  +++e+i 
  EEA19094.1  28 WVPSSDgKKIASINPTNETEIVSVHAASTADIDKAVAAARAALIspSWRDLPASDRGKLLYKLADIVEENRLMLATIETWDNGKPFTVARDeDLTEVIG 126
                 899999677********************************986569********************************************9******* PP

                 HHHHHHHHHHHHSEEEEEECTTEEEEEEEEE-SEEEEEE-SSSCCHHHHHHHHHHHHTT-EEEEEE-TTSHHHHHHHHHHHHHTTS-TTSEEE--SSTC CS
      Aldedh  96 vlryyaelaeklegevlpssegklalvrrePlGvvgaItPWNfPlllaawklapalaaGNtvvlKPaeetplsalllaelfeeaglPkgvlnvvtgsgs 194
                 +lryya++a+k  g+v+ ++++k+a++ reP+Gv+g+I+PWN+Pl++aawkl pala+GNtvvlKPae+tpls+l++a+l  eag+P+gv+n+v+g+g+
  EEA19094.1 127 TLRYYAGWADKSFGQVIDTTPDKFAYTLREPVGVCGQIIPWNYPLSMAAWKLGPALACGNTVVLKPAEQTPLSILYFANLTIEAGFPPGVINIVNGHGR 225
                 *************************************************************************************************** PP

                 CHHHHHHH-TTESEEEEES-HHHHHHHHHHHHCTTSEEEEEE---EEEEE-TTSHHHHHHHHHHHHHHGGGGTSTTSEEEEEEEHHHHHHHHHHHHHHH CS
      Aldedh 195 evgealvehpevdkvsftGstevgrkiakaaaknlkrvtlElGGknplivledaDldkaveaivkgafgnaGQvCiaasrllvqesiydefveklveaa 293
                  +g+al++hp+vdkv+ftGst+++r+i+k aa++lk++tlE+GGk+pliv++daDld av ++  g+++n+GQ+C+a+sr+lvq+++yd+f+ek+++++
  EEA19094.1 226 IAGAALASHPNVDKVAFTGSTATAREIMKMAASTLKNITLETGGKSPLIVFNDADLDLAVGWAHIGIMSNQGQICTATSRILVQDDVYDAFLEKFKAQI 324
                 *************************************************************************************************** PP

                 HT-.-BS-TTSTT-SB---SSHHHHHHHHHHHHHHHHTTSEEEE-TTE.SB-SSSTTEE--EEEES-TTTSHHHHS---SSEEEEEEESSHHHHHHHHH CS
      Aldedh 294 kkl.kvgdpldedtdvGPliseaqlekvekyveeakeegaklllGgereeaglekgyfvePtvlanvtpdmriaqeEiFGPVlsvikfkdeeeaieiaN 391
                 k++ kvgdp+de+t  GP++++aq++++++yv+ +k+egakl+lGg+   a ++kg+f+ePtv+++v+++mri+qeE+FGP +++ +fk+eeea+++aN
  EEA19094.1 325 KNIsKVGDPFDEATFQGPQVTKAQYDRIMSYVDIGKSEGAKLVLGGKP-AAPEAKGFFIEPTVFTDVKSQMRIYQEEVFGPFVCLARFKTEEEALKMAN 422
                 **********************************************64.7889********************************************** PP

                 SSSEESEEEEE-SBHHHHHHHHHHS-SSEEEESSSST--TTTSEB--CGGGEES-BSHHHHHHHTEEEEEE CS
      Aldedh 392 dteyGLaagvftkdleraervaerleaGnvyiNdsttgaaealpfgGvkqSglGreggkegleeytevktv 462
                 dt yGL++++ft+dl +a+rva+r+eaG+v+iN+s++++    pfgGvk Sg+Gre g+egl++y++vk+v
  EEA19094.1 423 DTTYGLGSALFTTDLVKAHRVARRIEAGMVWINSSNDSDWRI-PFGGVKGSGIGRELGEEGLKAYSQVKSV 492
                 ******************************************.**************************97 PP

>> DUF1487  Protein of unknown function (DUF1487)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   0.0   0.00075       4.5       8      62 ..     273     329 ..     269     333 .. 0.80
   2 ?    1.9   0.0     0.022   1.3e+02     117     170 ..     406     458 ..     389     464 .. 0.89

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.00075
     DUF1487   8 mvifedgDlnsale.alveslk.ePfaegavatvlveesirdefvervrsklkplse 62 
                 +++f+d+Dl+ a+  a +  +  +   + a   +lv++ + d f+e+ ++++k++s+
  EEA19094.1 273 LIVFNDADLDLAVGwAHIGIMSnQGQICTATSRILVQDDVYDAFLEKFKAQIKNISK 329
                 799*******99852334455414555788999********************9986 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.022
     DUF1487 117 vTlhtFrnakEvvkllakeslkfasvsvwneklaavyelvarlnvdvftiNCak 170
                 v l  F++ +E+ k+++  +  + s +++   l +++ ++ r++  ++ iN  +
  EEA19094.1 406 VCLARFKTEEEALKMANDTTYGLGS-ALFTTDLVKAHRVARRIEAGMVWINSSN 458
                 77899**********9999999988.689999***************9999765 PP

>> SVS_QK  Seminal vesicle protein repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.1    0.0075        45       3       9 ..     136     142 ..     136     142 .. 0.90
   2 ?   -3.0   0.1       2.9   1.7e+04       9      12 .]     390     393 ..     387     393 .. 0.75
   3 ?    4.6   0.1      0.01        60       3      11 ..     483     491 ..     483     491 .. 0.92

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0075
      SVS_QK   3 lKSFgQe 9  
                 +KSFgQ+
  EEA19094.1 136 DKSFGQV 142
                 6*****7 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 2.9
      SVS_QK   9 eKSq 12 
                 +KSq
  EEA19094.1 390 VKSQ 393
                 8999 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.01
      SVS_QK   3 lKSFgQeKS 11 
                 lK ++Q+KS
  EEA19094.1 483 LKAYSQVKS 491
                 799*****9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (500 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       494  (0.0275531); expected 358.6 (0.02)
Passed bias filter:                      461  (0.0257125); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 3257.93
//
Query:       EEA19095.1  [L=921]
Description: PX domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.8e-133  444.8   3.0   1.8e-133  444.8   3.0    2.0  2  DUF3818   Domain of unknown function in PX-proteins (DUF3818)
    4.9e-39  133.3   0.6      9e-39  132.4   0.6    1.5  1  PXB       PX-associated
    9.4e-11   41.7   1.1    2.8e-10   40.2   0.0    2.4  3  PX        PX domain


Domain annotation for each model (and alignments):
>> DUF3818  Domain of unknown function in PX-proteins (DUF3818)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  444.8   3.0  2.9e-137  1.8e-133       1     339 []     436     770 ..     436     770 .. 0.99
   2 ?   -0.5   0.5     0.084     5e+02     121     196 ..     791     870 ..     785     913 .. 0.70

  Alignments for each domain:
  == domain 1  score: 444.8 bits;  conditional E-value: 2.9e-137
     DUF3818   1 gLsklfeeikekesieelspelkkliewarielAstlyqvFvgsdnsselfaqlkrlhklmPYfllkqiLritNpmaimkglldLfLaqPfggrsLlqr 99 
                 gL+klf+eikek++i+elspe++k++ew+rie+A+t+y++F+++dns+elfaq+kr+h+l+PY++lk+++ri+Np+a+m+g+ldLfLaqPfg+rsLlqr
  EEA19095.1 436 GLTKLFAEIKEKNTIQELSPEYQKFAEWLRIEVAATIYHIFLAEDNSPELFAQAKRIHSLIPYTILKNVIRIANPAAVMSGVLDLFLAQPFGSRSLLQR 534
                 89************************************************************************************************* PP

     DUF3818 100 ifstilnedlkelekeikelekkidkseelieklkkfveaseeeqeeireeseeekldllvvilrseel.pklskeqleeviesykaykeakkeeksas 197
                 ifs++l++++k+++k i++l +k++ +++++eklk+fv+++e  ++ ir+e+++e++d++v+ilrse l p+++++q+e+++++y a+++a+++     
  EEA19095.1 535 IFSMTLTDGIKQFQKPIDTLVAKVE-DPVICEKLKAFVDSDEPLKTVIRDEAQAEDVDIVVAILRSELLtPEMKPSQIEKIFNAYVAWNAAVEN----V 628
                 *************************.***************************************************************99888....8 PP

     DUF3818 198 ekeenedaelfedlkellklylrerDkellikllqepelsellkdiitifyeplvrvykaanisdalkdfqkFlndliklveklkneeqesdpanvvqa 296
                  ++ +++ae+f++lk+llkly+r+rDk ++ ++++ep++++l++d++tifyeplvrvyk+an++++++df+kF +d i ++ek + ++ ++dp+++vqa
  EEA19095.1 629 YEDLKHGAEWFAYLKQLLKLYTRQRDKAMMLSMIEEPTTLRLFRDLFTIFYEPLVRVYKSANVYNSITDFAKFAEDAIGVIEKAQRQDVSADPNQTVQA 727
                 9999******************************************************************************88888877********* PP

     DUF3818 297 fidLvdrhedsfykFvhevyvkdeelfdelikWiekilkflre 339
                 fidL++rhe++fykFvhev+ +d++lf +l++Wie+il+flr+
  EEA19095.1 728 FIDLCARHEHNFYKFVHEVHLHDNGLFGSLMAWIENILDFLRK 770
                 *****************************************95 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.084
     DUF3818 121 kkidkseelieklkkfveasee....eqeeireeseeekl.dll.vvilrseelpklskeqleeviesykaykeakkeeksa 196
                 k+id +ee i++++  v+ +e+    +++++r++ ++e++ +++  + +r++++  l++++l++++  +++ +e  +++++ 
  EEA19095.1 791 KQID-KEETIREIDSLVKWQEDrkkwHHDKTRQKMAAEGTgEMTgSATFRTSDF-GLDEDDLDDLAITNEESDEDDENSEDD 870
                 4677.8999999999999888877787788888888887764441556677776.577777777777776666555554444 PP

>> PXB  PX-associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.4   0.6   1.5e-42     9e-39       3     129 ..      31     154 ..      29     155 .. 0.93

  Alignments for each domain:
  == domain 1  score: 132.4 bits;  conditional E-value: 1.5e-42
         PXB   3 seLtplqehyLkkiLihlelykElealkdpdalsklGyPFkseekekkekkeaesselPllrfllrefvltfPfl.kalpkefWqdkvqpfleslaean 100
                 + Lt +qehyLk++L++ ++++E+ +l +p+al+++G+PFkse  e     +  +selP+lrf++ ++v +fPfl +a +kefWqd++q+fles+a++n
  EEA19095.1  31 NILTGKQEHYLKRELLNAQVRREIIELAHPTALQRFGAPFKSEFGE----VAPVDSELPILRFIFVNHVRNFPFLdQAREKEFWQDRLQVFLESFASKN 125
                 679**************************************96532....335677*******************99999******************* PP

         PXB 101 lSesydkgeltkrkklatklskllellvr 129
                 +S+s+d+ e tkr+kla+k++kl+el++ 
  EEA19095.1 126 ISSSEDRLEETKRRKLAKKCEKLVELMMV 154
                 **************************986 PP

>> PX  PX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0      0.94   5.6e+03      47      90 ..      41     117 ..      39     133 .. 0.59
   2 !   40.2   0.0   4.6e-14   2.8e-10      10     112 ..     208     379 ..     200     380 .. 0.92
   3 ?   -3.9   0.1       2.3   1.4e+04      78      93 ..     411     426 ..     406     429 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 0.94
                 HHHHHHHHHTTSTSTSSSTSGSSSSS....................................CTTSHHHHHHHHHHHHHH CS
          PX  47 LhskLlrkfprvkiPplPkkvlfgsv....................................rkkdeefiekrrkgLeey 90 
                 L+++Ll+  +r++i +l ++  ++++                                    ++ ++ef++ r   L+++
  EEA19095.1  41 LKRELLNAQVRREIIELAHPTALQRFgapfksefgevapvdselpilrfifvnhvrnfpfldQAREKEFWQDR---LQVF 117
                 5666666666666666666666665555555555555666666666666666666666666656666666655...4444 PP

  == domain 2  score: 40.2 bits;  conditional E-value: 4.6e-14
                 EEEEE.TTSSEEEEEEEEEETTSSSEEEEEEEHHHHHHHHHHHHHHHTTSTSTSSSTSGSSSSS................................... CS
          PX  10 erets.gskkhsyylyevelktgakewtvkRrYsdFeeLhskLlrkfprvkiPplPkkvlfgsv................................... 72 
                  +++  + ++h  ++ +v+   +     v RrY dF++Lh++++ + p+ ++PplP+k+  +s+                                   
  EEA19095.1 208 SVKRTvRYHQHAEFILRVRKAGQ-PDIYVGRRYGDFVKLHKRIRTELPGKMLPPLPRKNKKSSSvsfwggsgdddassisslstsggtivvdddraaas 305
                 43333478889999999998875.999********************************88777*********************************** PP

                 ..................................CTTSHHHHHHHHHHHHHHHHHHHTSCHHHHSHHHHHHHHS CS
          PX  73 ..................................rkkdeefiekrrkgLeeyLqrllnhpelrnsevlteFLev 112
                                                   r+ +    e++r +L ++L+ +l+++   +s+++ +FL+ 
  EEA19095.1 306 rsnltlaiperrrsnsrssalsvrsvsprasgdfRRGTFLYREEQRVSLRAFLRTILQNKRVAESKAMEDFLTA 379
                 ********************************999999999*******************************85 PP

  == domain 3  score: -3.9 bits;  conditional E-value: 2.3
                 HHHHHHHHHHHHHHHH CS
          PX  78 efiekrrkgLeeyLqr 93 
                 e++++r ++L++y+++
  EEA19095.1 411 EIARQRAAELDVYMEK 426
                 678899999**99987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (921 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       836  (0.0466284); expected 358.6 (0.02)
Passed bias filter:                      482  (0.0268838); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.74u 0.30s 00:00:01.04 Elapsed: 00:00:00.49
# Mc/sec: 5617.38
//
Query:       EEA19096.1  [L=480]
Description: MFS drug transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.8e-23   82.0  41.7    7.2e-23   81.1  37.9    2.6  2  MFS_1     Major Facilitator Superfamily
    2.9e-08   33.0  19.0    7.5e-05   21.8  11.1    2.4  2  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.1  37.9   8.1e-27   7.2e-23       4     351 ..      56     387 ..      53     389 .. 0.81
   2 ?   -1.1   0.1     0.077   6.9e+02     150     171 ..     447     467 ..     438     477 .. 0.55

  Alignments for each domain:
  == domain 1  score: 81.1 bits;  conditional E-value: 8.1e-27
       MFS_1   4 aaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgagal 102
                  ++ls+++ +i+ +++  +++++++ ++ ++++l+t y +++ ++++++Gr+sd fGr++++ ++ ++f+lg+l + +a+ ++ l ++r+++G+g+   
  EEA19096.1  56 NVLLSGFDGTITVSTYA-LISSEFN-AANTASWLTTSYLITSTAFQPIYGRMSDIFGRKPCFYVCTVSFLLGCLGCGVAQDVFSLNIMRAITGIGG--- 149
                 67899999999999999.9******.9999******************************************78888768888************6... PP

       MFS_1 103 fpagaaliadwfpkeergraigllsagfslGailgpllgglla.sslg.........Wravfyilaivsllafvlfllllpeepperkrkspkeeekgt 191
                    g+ ++ + +++ +  + +g+ ++  ++ ++ + ll  +l+ +++g         W+ ++++  +++ + ++  +l+l++e+++++ +         
  EEA19096.1 150 ---GGLITMEKSND-HVYSTLGWRGIWQQVDILGTVLLVLALSvQLVGlslggnelpWSNPWIVSSLIGSMILL--ALFLWTEARTSAAP--------- 233
                 ...33333444444.55555555555555555544455554554444455669***************999955..59999999999987......... PP

       MFS_1 192 gpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrll.lallllllaal 289
                     ++p +++l    ++  + ia l++++g +++l+ lpl++q vl  s + +ag+ l +++l++ +++l+ag ++ r+gr  +++ ++ ll++++ l
  EEA19096.1 234 ----IIP-LRLLQGTVPIC-IQIANLCVGMGAYAFLFNLPLFFQVVLLDS-ASTAGARLVIPSLATPVGGLIAGIIMSRWGRLSQIVqMGALLMFIGNL 325
                 ....677.88888888885.8888889999************99999999.8******************************65555277777778888 PP

       MFS_1 290 glallavtssavllllvlvl.iGfglgfvfpsllalasdlappeeagtasglfntagslggal 351
                 ++all +  +a + ++v+v+ + +g+g+v+p +l      +    ++  s+ + +++slg + 
  EEA19096.1 326 LVALLRFN-DANWKYFVYVFpANLGQGMVYPGILFSFLATFDHTDHAVSSSTVYLIRSLGNVW 387
                 88888888.777777777775888*****9999999988887777777777777888888765 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.077
       MFS_1 150 Wravfyilaivsllafvlflll 171
                  r +f + a ++++a++ ++l+
  EEA19096.1 447 LRMSFALSASLCAIAAL-GALF 467
                 34455555555555544.2222 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8  11.1   8.3e-09   7.5e-05       3     122 ..      50     155 ..      48     231 .. 0.74
   2 !   15.8   1.0   5.4e-07    0.0048      45     107 ..     278     341 ..     255     357 .. 0.81

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 8.3e-09
                 HHHHHHH.HHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTS CS
    Sugar_tr   3 lvaalgg.llfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgkn 100
                 +va+l+  ll g+d  +  ++++l++  ++f++ ++           ++++ ++l+ +++ + + g ++d+fGRk+++ +++v f+ g + +++a+   
  EEA19096.1  50 QVAILANvLLSGFDGTITVSTYALIS--SEFNAANTA----------SWLTTSYLITSTAFQPIYGRMSDIFGRKPCFYVCTVSFLLGCLGCGVAQ--- 133
                 68888888888999888888888888..555555444..........5999*********************************************... PP

                 S-TGGGGGHHHHHHHHHHHHHH CS
    Sugar_tr 101 svevlivgRvlvGigvGlasvl 122
                  v  l ++R ++Gig G+  ++
  EEA19096.1 134 DVFSLNIMRAITGIGGGGLITM 155
                 99**************998766 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 5.4e-07
                 ..HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHH.HHHHHHHHHHHHH-TTTTSS-TGGGG CS
    Sugar_tr  45 svlsglivsiflvGaiiGslfagllgdrfGRkkslli.aavlfvigavlqaaakgknsvevliv 107
                 +++ g+ + i ++   +G+l+ag+++ r+GR + ++  +a+l++ig++l a+   + + + ++v
  EEA19096.1 278 ASTAGARLVIPSLATPVGGLIAGIIMSRWGRLSQIVQmGALLMFIGNLLVALLRFNDANWKYFV 341
                 455688889999*******************9888754999**********9998877777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (480 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       582  (0.0324614); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.25s 00:00:00.80 Elapsed: 00:00:00.41
# Mc/sec: 3497.35
//
Query:       EEA19097.1  [L=353]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.1e-07   30.0   5.1    6.7e-07   29.3   5.1    1.4  1  zf-GRF    GRF zinc finger
  ------ inclusion threshold ------
      0.015   14.1   4.1      0.024   13.4   4.1    1.4  1  SLD3      DNA replication regulator SLD3


Domain annotation for each model (and alignments):
>> zf-GRF  GRF zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.3   5.1   7.5e-11   6.7e-07       3      44 ..      26      69 ..      24      70 .. 0.75

  Alignments for each domain:
  == domain 1  score: 29.3 bits;  conditional E-value: 7.5e-11
      zf-GRF  3 Ckcg.rlavllt.vrktgpNkGRkFYkCpkgkekqCgFFkWade 44
                C c  rl       ++ g N+GR FY+C k++ k C FF W d+
  EEA19097.1 26 CDCDpRLPADHFqTKNGGVNHGRWFYTCQKPQLKRCKFFLWDDD 69
                6666544333330345789**********************996 PP

>> SLD3  DNA replication regulator SLD3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   4.1   2.6e-06     0.024     449     514 ..     223     290 ..      58     329 .. 0.61

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 2.6e-06
                 XXXXXXXXXXXX.XXXXXXXXXXXXXX......................XXXXXXXXXXXXXXXXXXXX CS
        SLD3 449 srkskkpvrkpl.aqtvqVkATPkknrkkDvla..kaeeesetaasaseetepaksssaqvvPsstlrk 514
                  + +++++ +p+ +++v+V+ATP  +r kDvl+   a ++++ ++ as+  ++    ++ vvP+++ ++
  EEA19097.1 223 PTTQSSSTTAPFaFSSVEVSATPTPRRYKDVLSaqGAGSHNQPSDLASNILSIL-DRHDVVVPTTARDE 290
                 2223333333334777****************9653333333455556656664.67788889887544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (353 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       920  (0.0513135); expected 358.6 (0.02)
Passed bias filter:                      525  (0.0292822); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.30s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 2353.90
//
Query:       EEA19098.1  [L=497]
Description: tRNA (guanine) methyltransferase Trm5 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-67  226.4   0.0    4.7e-67  225.6   0.0    1.4  1  Met_10    Met-10+ like-protein
  ------ inclusion threshold ------
      0.065   12.4   0.0       0.13   11.4   0.0    1.4  2  TRM       N2,N2-dimethylguanosine tRNA methyltransferase


Domain annotation for each model (and alignments):
>> Met_10  Met-10+ like-protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  225.6   0.0   5.3e-71   4.7e-67       2     197 ..     168     424 ..     167     426 .. 0.93

  Alignments for each domain:
  == domain 1  score: 225.6 bits;  conditional E-value: 5.3e-71
                 EEEEETTEEEEEB-TTSSHHHHHHHHHHHHHS.S-SCEEEE-S-S..BTTTTB--EEEEEES-.SEEEEEETTEEEEEETTTS---GGGHHHHHHHHTT CS
      Met_10   2 kfeiiGdvvilnlreelkeykkvigevildkt.kvktvlrkvsev..egefRtfelevlaGsdstetihkEngcrfklDvskvyfsskleaErerlakl 97 
                 +f+ +G+v++lnlre+  +yk++i+e++ dk+ kv+tv++k++ v  e+efRtf++e+laG++++++ ++E+gc+f++D+s+vy++s+le+E++rl  +
  EEA19098.1 168 GFTLTGHVLHLNLRERWYPYKHLIAEILKDKNpKVRTVINKTKVVgsESEFRTFPFEILAGDNDMNVTVHEQGCEFQFDFSRVYWNSRLETEHRRLCDK 266
                 699*****************************************9999*************************************************** PP

                 --TT-EEEETT-TTTCCHHHCCHHTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EE.......................... CS
      Met_10  98 veegevVvdvfAGiGpfaipiakyskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqlad.......................... 170
                 ++ege+V+dv+AG+Gpfa+p++k  ++ +v+a+dlnP+ ++ +++++++Nkv++ v+p+++Dgr++ire++                            
  EEA19098.1 267 FKEGELVCDVMAGVGPFAVPAGK--RKIFVWANDLNPHGFESMEDAVTRNKVHQFVTPFNMDGRKFIRESAKMitspattvviqpripaslkrakldgs 363
                 ***********************..******************************************866555789*********************** PP

                 ..................EEEE--TTTGGGGHHH...HHHHEEEE.............EEE CS
      Met_10 171 ..................rvvmnlpksaieFldk...vlaalkdg.............gvi 197
                                   ++vmnlp++aieFld+   v++ ++ +             +v 
  EEA19098.1 364 grtpapppqiftrpptvnHYVMNLPATAIEFLDAfvgVYTGMETRfepydpeqklpmiHVY 424
                 *********************************9555555554445555555555555555 PP

>> TRM  N2,N2-dimethylguanosine tRNA methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.1   0.0      0.73   6.5e+03     325     349 ..     189     213 ..     184     216 .. 0.81
   2 ?   11.4   0.0   1.5e-05      0.13      75     117 ..     292     334 ..     260     339 .. 0.90

  Alignments for each domain:
  == domain 1  score: -4.1 bits;  conditional E-value: 0.73
                 HHHHHHHT-SS---HHHHHHH.... CS
         TRM 325 sqlasvlklsvpplkkvvsalkelg 349
                 + +a++lk + p++++v+++ k +g
  EEA19098.1 189 HLIAEILKDKNPKVRTVINKTKVVG 213
                 6689999999999999999987766 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 1.5e-05
                 EEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HHHHHC-- CS
         TRM  75 kevlaNDisekAvelikeNvklneveeivvineddAnvllaek 117
                   v+aND++++  e+++  v+ n+v++ v++ ++d + +++e 
  EEA19098.1 292 IFVWANDLNPHGFESMEDAVTRNKVHQFVTPFNMDGRKFIRES 334
                 4699********************************9999865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (497 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       417  (0.0232584); expected 358.6 (0.02)
Passed bias filter:                      405  (0.0225891); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.72u 0.37s 00:00:01.08 Elapsed: 00:00:00.59
# Mc/sec: 2531.84
//
Query:       EEA19099.1  [L=150]
Description: polymerase (RNA) II (DNA directed) polypeptide D [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.7e-25   89.7   4.9    2.7e-25   89.1   4.9    1.3  1  RNA_pol_Rpb4  RNA polymerase Rpb4
     0.0006   19.5   1.6    0.00074   19.2   1.6    1.2  1  Cut8          Cut8, nuclear proteasome tether protein
  ------ inclusion threshold ------
      0.038   13.0   0.2      0.042   12.9   0.2    1.1  1  TROVE         TROVE domain


Domain annotation for each model (and alignments):
>> RNA_pol_Rpb4  RNA polymerase Rpb4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.1   4.9   4.5e-29   2.7e-25       2     122 ..      39     145 ..      38     146 .. 0.92

  Alignments for each domain:
  == domain 1  score: 89.1 bits;  conditional E-value: 4.5e-29
                   E-HHHHHHHHHHHHHHHHCHHHHHTCCCCCHHSHCHTCHHCHHHHHHHHHHHCTHHTTSSHHHHHHHHHHHT.TSTSTHHHHHHHHHCSTSSHHHHH CS
  RNA_pol_Rpb4   2 LsnsEvllvlkeeleerknkdkkeseddkisekeevkgnlnkilkktleyltnkfsrlkneekfnelvellk.sfeLtkaEklqlvnlkPesavelk 97 
                   Ls+sE++lv+++ le++++  k              k +  + l ktl+yl+  fsr+k+ee+++++ +ll+ ++eL+ +E+ ql++l++++a+e+k
    EEA19099.1  39 LSLSEARLVINKVLENKRRSGK--------------KYDEPENLTKTLDYLEV-FSRFKDEENIKAVERLLNsHTELEMFERSQLGSLCCDNAEEAK 120
                   9**********99999977753..............3455677899******9.******************6777********************* PP

                   HHSTTGTTTSTSHHHHHHHHHHHHH CS
  RNA_pol_Rpb4  98 tlieeleerfedeqleeiLdelkev 122
                   +li++l+++++d +l+e+Ldel+++
    EEA19099.1 121 SLIPSLQNKISDIDLQELLDELTKL 145
                   **********************997 PP

>> Cut8  Cut8, nuclear proteasome tether protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   1.6   1.2e-07   0.00074      38     103 ..      55     146 ..      10     149 .. 0.69

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 1.2e-07
        Cut8  38 k..........................krsrtpkisgqpLplsrlLetLdkeqLqsllqslveehpeleqevskkapkpsiesllelLkekk 103
                 k                          k ++++k   + L+ ++ Le+ +++qL sl+ +  ee  +l  ++++k++  ++++ll++L +++
  EEA19099.1  55 KrrsgkkydepenltktldylevfsrfKDEENIKAVERLLNSHTELEMFERSQLGSLCCDNAEEAKSLIPSLQNKISDIDLQELLDELTKLR 146
                 0222333333344444566666776666566777999***************************************************9886 PP

>> TROVE  TROVE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.2     7e-06     0.042     201     263 ..      49     109 ..       8     119 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 7e-06
       TROVE 201 navkerkkaeta.ekka.keeskkltlkklvqrlhisepaeevqallGkkyPsnlqlfsrsrlpg 263
                 n+v e k ++++ + ++ ++  k l ++++++r + +e+ + v +ll + +  +l++f rs+l g
  EEA19099.1  49 NKVLENK-RRSGkKYDEpENLTKTLDYLEVFSRFKDEENIKAVERLL-NSH-TELEMFERSQL-G 109
                 4444444.22221222235899*************************.999.99********9.4 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (150 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       803  (0.0447878); expected 358.6 (0.02)
Passed bias filter:                      460  (0.0256568); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.48
# Mc/sec: 937.57
//
Query:       EEA19100.1  [L=803]
Description: C6 transcription factor (OTam), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      1e-18   67.3   0.0    2.1e-18   66.3   0.0    1.5  1  Fungal_trans  Fungal specific transcription factor domain
     0.0019   18.3   5.0     0.0033   17.5   5.0    1.3  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
        7.6    6.5  14.7        6.5    6.7   1.0    2.3  2  Ashwin        Developmental protein


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.3   0.0   3.5e-22   2.1e-18       2     241 ..     300     521 ..     299     550 .. 0.87

  Alignments for each domain:
  == domain 1  score: 66.3 bits;  conditional E-value: 3.5e-22
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilq.sL 97 
                   d ff+ +hp fp+l ++sf  ++     +  +  splll+a++ l   ++e e +  ++ + +++++       a++l+    s p  +++++q   
    EEA19100.1 300 DKFFEKIHPVFPVLMEDSFRQSY-----RTRRGLSPLLLAAVYTLTLKYLEFEPAARSARKPDVKRMED----TAMKLL--TESLPHADITTIQaGM 385
                   67*********************.....99999************************999999999999....999999..89999999*****667 PP

  Fungal_trans  98 lllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlp.LPcddddlw 193
                   l+++  ++++s+      + g  v+ a +lgLh++ ++++       + +e+  rrR++wa    Dk+++l++Grp+++++ + +++ L +dd  ++
    EEA19100.1 386 LIMQRSSLNTSS------LNGQLVTAAFELGLHQDCFNWK------IPLAERGLRRRMAWALHTQDKWCSLVHGRPSHMSAANWTVRdLVEDDF-IG 469
                   888888888887......99********************......*****************************************5555555.55 PP

  Fungal_trans 194 esddaseetlvetk....lsneeksrkiasfllaLkkilskiagsllsiekq 241
                     +++s  +++ +      +   ++++ + +++aL  il++i++++++++  
    EEA19100.1 470 AFSSTSPANKRLDTestdGNGLGHGPLLFCQHVALTAILAEILDTFYTLRAA 521
                   555555555554445999999999999999**************99887765 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   5.0   5.5e-07    0.0033       2      34 ..     123     156 ..     122     161 .. 0.83

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 5.5e-07
                 S-HHHHHCT---ST...SSSS-HHHHHCTHHHCCCC CS
     Zn_clus   2 aCdnCrkkKvKCda...kkPaCsnCkklnleCtfys 34 
                 +Cd C  +K++C +      +C +C+ ++ +Ct +s
  EEA19100.1 123 SCDACLFRKSRCAMnelV-NKCYSCEFHRQDCT-FS 156
                 9************97533.33************.44 PP

>> Ashwin  Developmental protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   6.8     0.006        36     120     186 ..      40     102 ..      22     118 .. 0.63
   2 ?    6.7   1.0    0.0011       6.5      75     157 ..     161     243 ..     146     284 .. 0.66

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.006
      Ashwin 120 LkpPpasknlsnpirklsssssssssssslsseptdl...ssneekqnssvttekspvankkvvkssths 186
                  + P  s ++++p+ +l++s+s ss+s s+ ++p+++   +   + ++s v   +s++an+++ +++  +
  EEA19100.1  40 HQHPRMS-STTSPVTSLTNSPSASSASFSSVATPNTVpaiN---TGATS-V--ATSTSANHSALNNTIAA 102
                 3445555.7888***********999999999999994332...22222.2..22333334433333333 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0011
      Ashwin  75 skksasvdgsRkrplIvfdg.sstkt.siklkktendlsasgeasdrLkpPpasknlsnpirklsssssssssssslsseptdl.......s 157
                    +a++ +sRkr l  f    stk  si + ++e+     +++   + pPp++  ++n+   l+s   s  +ss++   +t+l        
  EEA19100.1 161 ALTEATSPQSRKRKLEDFVEaESTKRqSIEVPRPES-----ATK--EMVPPPTT-ATTNNTNLLASPRLS-YQSSQHIGLTTELepilfehI 243
                 4455666699999996654414565569*******9.....444..67899988.566666666555544.555667777777744444430 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (803 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       838  (0.0467399); expected 358.6 (0.02)
Passed bias filter:                      488  (0.0272185); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.73u 0.28s 00:00:01.01 Elapsed: 00:00:00.47
# Mc/sec: 5139.71
//
Query:       EEA19101.1  [L=617]
Description: 60S ribosomal protein Nsa2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.6e-43  148.2   1.7    2.7e-43  147.4   1.7    1.3  1  Ribosomal_S8e  Ribosomal protein S8e
    1.7e-12   47.2   0.0    2.8e-12   46.6   0.0    1.2  1  PfkB           pfkB family carbohydrate kinase


Domain annotation for each model (and alignments):
>> Ribosomal_S8e  Ribosomal protein S8e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  147.4   1.7     3e-47   2.7e-43       4     137 .]     388     616 ..     385     616 .. 0.96

  Alignments for each domain:
  == domain 1  score: 147.4 bits;  conditional E-value: 3e-47
                    BXXCCCSEESSTEEXXXSSXXX...................................................CCSBXXXXXXXEE.......... CS
  Ribosomal_S8e   4 srdskhkrkltGgkakllrkkr...................................................kielgrkekatkl.......... 38 
                    +  s+++++l+G++ak++++kr                                                   +i+ +r eka+k+          
     EEA19101.1 388 HLASQKAQSLRGLRAKMYAQKRhaekiqmkkriraqeeknvksaapsepssatplpnylldrsqatnakalssAIKDKRSEKAAKFsvplpkvkgi 483
                    66899*********************************************************************************9999999876 PP

                    .SSHEEEEEEETTCEEEE...............................EEESESEEEEEETTTTEEEEEEEEEEECSSSTCHHHHTTC--TTEEE CS
  Ribosomal_S8e  39 .gaervkvvrvrgGkrkk...............................ralrlkkanvthpeekvtkklkIlgVkknpsnneyvrlgvltKgaii 102
                     ++e++kvv  ++Gk+ +                               ++lr+kkanvthpe++vt++l+Il+Vkknp+n++y++lgvltKg++i
     EEA19101.1 484 sEEEMFKVV--NTGKKTHkkswkrmitkptfvgqdftrrnpkferfirpMGLRYKKANVTHPELGVTVQLPILSVKKNPQNPLYTQLGVLTKGTVI 577
                    55*******..666544446**************************************************************************** PP

                    EEESHHHHHHHHTTEEE....EEEESEHHHHSSEEEEEE CS
  Ribosomal_S8e 103 evdvseLgevtqsgkvv....AqvtsrPgqdGcvnavlL 137
                    ev+vseLg+vt+sgkvv    Aqv+++P+ dG vnavlL
     EEA19101.1 578 EVNVSELGLVTTSGKVVwgkyAQVSNNPDLDGTVNAVLL 616
                    **************************************8 PP

>> PfkB  pfkB family carbohydrate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.6   0.0   3.1e-16   2.8e-12      52     295 ..      51     308 ..      27     313 .. 0.79

  Alignments for each domain:
  == domain 1  score: 46.6 bits;  conditional E-value: 3.1e-16
                 EEEEEEEEESSHHHHHHHHHHHHTTEEETTEEEESSSEEEEEEEEETTT.SEEEEEEEEGGGGGHHHHHHHHHHHHHGCTSEEEEESEECTTSHHHHHH CS
        PfkB  52 dvafigavGdDnfGeflleelkkegvdtdyvkidedtrtglalivvded.gertivfnrgaaadltkeeleededlleeadllyisgllsselpeavle 149
                 +  +i ++G+D+  +++++ l + g      +  ++ +t   l   d++ g+ t+ +  +    +t++    + ++l  a+ +++    +++l e++ +
  EEA19101.1  51 SIGWIIQIGNDF-PSDIEDDLTALGTTLVIDRKLNQPSTRGLLEYKDSAfGQKTFQYITPVLRIQTEQ---LNNQALFTAKSFHLFE-WPQQLEERISN 144
                 566788888888.8888888888888887777777888888888888889999999999955555554...4888999999999998.89999999999 PP

                 HHHHHHHHTTE..EEEEECESSSHH....HHHHHHHHHCTESEEEEEHHHHHHHHTSCT......HSHHHHHHHHHHHHHTTS.....SEEEEEEGGGE CS
        PfkB 150 elaeaaknggt..fdpnlldplgaq....fkeallellaladllkpneeElealtgekl......edieealaalhklkakga.....ktvvvtlGkeG 231
                 +la  +++g      +++ +p++ +     ++ + ++  l+d++ pn+ El +++gek       +++e+++++l +    g+        ++  G+ G
  EEA19101.1 145 LLALRRQKGLVdqRPLIIWEPAPLScereQLSFFFSAAKLVDVFSPNHLELLRIFGEKPstpfdrTQVEDLARKLLE---LGVgpdrtGIMIIRSGEHG 240
                 9988888888888888888888888844444444466789*******************9**666555555555555...44433544789******** PP

                 EEEEETTEEEEEEE.....SSSS-SBGTTHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHTSSSS CS
        PfkB 232 alvvekdgelkvpav....pkvkvvDttGAGDsfvggflaallegksleealrfanavAalvvqkkga 295
                 +     +g+ ++ +      + kvvD tGAG +f g++++a+l+  + ++a+ +++ +A++++++ g+
  EEA19101.1 241 SMMLVAGGVPHWIPPyyqaSSLKVVDATGAGNAFLGAYAVAYLKTRDSQQAASYGSVAASFALEQIGV 308
                 *999955554444432444688*****************************************99886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (617 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       922  (0.0514251); expected 358.6 (0.02)
Passed bias filter:                      480  (0.0267723); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.43
# Mc/sec: 4340.81
//
Query:       EEA19102.1  [L=275]
Description: aconitate hydratase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.6e-08   34.0   0.0    4.5e-08   33.3   0.0    1.4  1  Ribosomal_L21p  Ribosomal prokaryotic L21 protein


Domain annotation for each model (and alignments):
>> Ribosomal_L21p  Ribosomal prokaryotic L21 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.3   0.0   2.5e-12   4.5e-08       2     100 ..     131     233 ..     130     234 .. 0.93

  Alignments for each domain:
  == domain 1  score: 33.3 bits;  conditional E-value: 2.5e-12
                     EEEEECSTEEEEESSSEEEEEESS..SSSTTCEEEESSEEE....EE.ECTSSSESS..TCEEEEEEEEEE---EEEEEEETTTTEEEEEEE--E CS
  Ribosomal_L21p   2 yAiietgGkqykVeegdvlkvekl..eaevgdkveldkVllvgskddvkvGaplveg..akVeaevvehgkgkkiivfkkkrrknyrrkqghRqk 92 
                     y+  +++++ y  +egd ++++ l  +++ gd +++++  ++gs+d ++ G+p++++   +++ +v+    ++  +  k krr ++ ++ + +++
      EEA19102.1 131 YISAHLHDRPYLLTEGDHIRLPFLmpKVKSGDILRFNRASVLGSRDYTLKGSPYIDErmYECRLRVLGVESEPLRVKEKTKRRRRHVQHIKSKHR 225
                     6667889999************9988999**************************985569********************************** PP

                     EEEEEEEE CS
  Ribosomal_L21p  93 ytklrItk 100
                     yt lr+ +
      EEA19102.1 226 YTILRVME 233
                     *****976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       852  (0.0475208); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2016.36
//
Query:       EEA19103.1  [L=529]
Description: aspartyl aminopeptidase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   6.3e-169  562.3   0.0   7.3e-169  562.1   0.0    1.0  1  Peptidase_M18  Aminopeptidase I zinc metalloprotease (M18)


Domain annotation for each model (and alignments):
>> Peptidase_M18  Aminopeptidase I zinc metalloprotease (M18)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  562.1   0.0  4.1e-173  7.3e-169       1     432 []      55     516 ..      55     516 .. 0.93

  Alignments for each domain:
  == domain 1  score: 562.1 bits;  conditional E-value: 4.1e-173
                    HHHH--SHHHHHHHHHHHHHCTT-EESTTTS-ST..STTCEEEEEEETTTEEEEEEEETTS-GGG--EEEEEE---SEEEEECCEEEEETTEEEEE CS
  Peptidase_M18   1 finksptpyhvvaevaekllkagfkelsekekwk..iepggkyfvtrngssliAFavgkkykaengfsiigaHtDsptlrvKpkskkkaegylqvg 94 
                    f+n+sptp+h+v+  +e l+ agf++++ek++w+   +pggkyf+trngs+liAFa+gkk+k++n ++++gaHtDsp lr+Kp+skk+ eg+ qvg
     EEA19103.1  55 FVNASPTPFHAVKSSKELLTAAGFEQIKEKDSWSstLQPGGKYFLTRNGSTLIAFAIGKKWKPGNSVAMVGAHTDSPVLRIKPISKKQGEGFVQVG 150
                    9*********************************877*********************************************************** PP

                    EEEESS.SSGGGTT--EEEEEEEEECTT--EEEEEECCSTT---BBB----GGG-GG..GSS--TTTTTSEEEEEEEE......------TTCCC. CS
  Peptidase_M18  95 vetYGggiwetWldrdLsvaGrvlvkkkkeekleaklvnierPvlriPnlaiHLdrdineefkfneetelepilglae......eeeeekedkek. 183
                    vetYGggiw+tW+drdL+vaGrv+v+ + ++ +++klv+++rP+lriP+laiHL+r+  e+f+fn+et+l pi gl e      +      d +  
     EEA19103.1 151 VETYGGGIWHTWFDRDLGVAGRVMVRAN-DGSIQQKLVKVDRPILRIPTLAIHLERK--ESFDFNKETQLFPIAGLVEaelnrtK------DYTPd 237
                    ***************************9.79*************************9..8****************986554331......22212 PP

                    ..............T.CCHHHHHHHHHHHHTS-CCCCCCCEEEEEE-S--EEETTTT-EEEESSHHHHHHHHHHHHHHCCCCHT..-TTTS-SEEE CS
  Peptidase_M18 184 ..............knkhkkalleliaeelgvevedivdlelilvdaqkakivGiekeflfaprlDnkvscfaaleallesaed..sleeedkvri 263
                                   ++h++ l+elia+e+   + di+d+elil+d+qk+ ++G+ +ef+f+prlDn+ ++f+a+++l+es  +   l++e+ +r+
     EEA19103.1 238 ssqqetpttslkptTERHHPYLVELIANEIDARPVDILDFELILFDTQKSCLGGLLEEFIFSPRLDNLNMSFCAVRGLIESVRSrkALDNESAIRL 333
                    3345567777766559*****************************************************************999889********* PP

                    EEEESSCCGTS-STTSGGCTHHHHHHHHHHHHHCSTT.........-HCHHHH...HC-EEEEE--EE---TTSGGGS-TTTS--TTSEEEEEEET CS
  Peptidase_M18 264 valfDnEEvGStsaqGadsnfleevlerisialkkse.........afeeavl...akSlliSaDvahaihPnysskheenhapllnkGvvikvna 347
                    +alfD+EE+GS+sa+Gads  l++vl+r+s+   k+          a+        + S+l+SaD+ah ++Pnys+k+e++h+pllnkG+vik+na
     EEA19103.1 334 IALFDHEEIGSKSAHGADSDALPAVLRRLSVLPAKEVgakavdlstAY----EqslTTSFLLSADMAHSVNPNYSAKYESDHKPLLNKGPVIKINA 425
                    ******************************998776555555333233....24559*************************************** PP

                    TSSSTT-HHHHHHHHHHHHHHC......-EEEEEEE-TTS----HCHHHHHHHHT-EEEEEE-EEBSTTSSSEEEECCHHHHHHHHHHHCC CS
  Peptidase_M18 348 nqryatnsagaallkevaqkan......vklQelvvrndspcGstigpilaaktGirtiDlGaaqlsmHSireltgskdveeavklfkaFf 432
                    nqryatn+ g++ll+evaqka       v+lQ +vvrnds cGstigp+l+a++G+rt+DlG++qlsmHSire+ g++dv +av lf +Ff
     EEA19103.1 426 NQRYATNAPGIVLLQEVAQKAVedggdvVPLQLFVVRNDSSCGSTIGPMLSANLGARTLDLGNPQLSMHSIRETGGTEDVGHAVRLFASFF 516
                    ********************97789999**************************************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (529 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       347  (0.0193541); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.46
# Mc/sec: 3421.42
//
Query:       EEA19104.1  [L=580]
Description: cell cycle regulatory protein (Srw1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    9.7e-25   86.4  11.5    2.5e-05   24.9   0.1    6.4  6  WD40         WD domain, G-beta repeat
    1.3e-14   54.2   5.8    0.00022   21.5   0.3    4.4  4  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
    7.3e-08   32.5   0.1      0.055   13.3   0.0    3.1  3  eIF2A        Eukaryotic translation initiation factor eIF2A
  ------ inclusion threshold ------
       0.02   13.9   0.0      0.062   12.2   0.0    1.8  2  Ge1_WD40     WD40 region of Ge1, enhancer of mRNA-decapping p
       0.18   10.7   1.1          1    8.2   0.1    2.2  2  PALB2_WD40   Partner and localizer of BRCA2 WD40 domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.8   0.6   0.00089       3.2      12      38 .]     317     344 ..     301     344 .. 0.85
   2 !    8.2   0.0    0.0013       4.7       4      34 ..     351     380 ..     348     381 .. 0.84
   3 !   19.7   0.0   3.2e-07    0.0011       2      38 .]     390     427 ..     389     427 .. 0.89
   4 !   24.9   0.1     7e-09   2.5e-05       2      38 .]     432     472 ..     431     472 .. 0.84
   5 ?    4.9   0.1     0.016        56       2      38 .]     477     515 ..     476     515 .. 0.76
   6 !   22.2   0.0   5.3e-08   0.00019       4      38 .]     522     557 ..     519     557 .. 0.88

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00089
                 S.EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  12 s.vtslafspdgawlasGsdDgtvriWd 38 
                 + vts+++ + g+ +a G+ +g v iWd
  EEA19104.1 317 DtVTSVSWIQRGTHIAIGTGKGLVQIWD 344
                 1599**9***********66*******9 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.0013
                 EEEEESS.SSEEEEEEETTSSE....EEEEETTSEE CS
        WD40   4 lrtltGH.ssvtslafspdgaw....lasGsdDgtv 34 
                 lrt  GH + v +l      aw    l+sG++D+ +
  EEA19104.1 351 LRTMIGHhNRVGAL------AWnehiLTSGGRDRLI 380
                 89999**999****......7777768899*9*976 PP

  == domain 3  score: 19.7 bits;  conditional E-value: 3.2e-07
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 q lr l GH + v++l+++ +   lasG+ D+++ +Wd
  EEA19104.1 390 QYLRRLAGHkQEVCGLKWNTEDGQLASGGNDNKLIVWD 427
                 5688999**777****999999999************9 PP

  == domain 4  score: 24.9 bits;  conditional E-value: 7e-09
                 EEEEEEESS.SSEEEEEEETTSSEEE.EEE..TTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawla.sGs..dDgtvriWd 38 
                 ++l+ ++ H   v ++a+sp+++ l+ sG+   D+t+++W+
  EEA19104.1 432 TPLHRFSQHtAAVKAIAWSPHQHNLLaSGGgtADRTIKFWN 472
                 689******777************752664447*******8 PP

  == domain 5  score: 4.9 bits;  conditional E-value: 0.016
                 EEEEEEESSSSEEEEEEETTSSEEEEE...ETTSEEEEEE CS
        WD40   2 qclrtltGHssvtslafspdgawlasG...sdDgtvriWd 38 
                 q++r+l++ s v+ l +s++++ l+s    s  + + iW+
  EEA19104.1 477 QLIRELDTGSQVCNLGWSKNSDELISThgyS-QNQIVIWK 515
                 6677775334699999*********953234.*******5 PP

  == domain 6  score: 22.2 bits;  conditional E-value: 5.3e-08
                 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 + +ltGH + v  la spdg+ +++G  D t+r+W+
  EEA19104.1 522 IVSLTGHtFRVLYLAISPDGQTIVTGAGDETLRFWK 557
                 6689***666****************66*******6 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.3   6.1e-08   0.00022      36      91 ..     314     368 ..     288     369 .. 0.88
   2 !   20.4   0.1   1.3e-07   0.00048      36      90 ..     397     450 ..     385     452 .. 0.93
   3 !   16.3   0.1   2.5e-06    0.0088      37      92 .]     440     496 ..     438     496 .. 0.85
   4 ?    3.1   0.0     0.034   1.2e+02      27      67 ..     520     558 ..     499     573 .. 0.77

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 6.1e-08
  ANAPC4_WD40  36 kedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgWge 91 
                   +d +v+s++W + g+ +a+++ +g v++ daes + ++++  +++ +v  l W+e
   EEA19104.1 314 LKDDTVTSVSWIQRGTHIAIGTGKGLVQIWDAESCRRLRTMIGHHN-RVGALAWNE 368
                  57899***********************************987777.7******97 PP

  == domain 2  score: 20.4 bits;  conditional E-value: 1.3e-07
  ANAPC4_WD40  36 kedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgWg 90 
                  ++++ev +L+W+ ++  La + +d+++ + d  +++ +h +s ++  av+ + W+
   EEA19104.1 397 GHKQEVCGLKWNTEDGQLASGGNDNKLIVWDKLNETPLHRFSQHTA-AVKAIAWS 450
                  6799***************************************999.6******7 PP

  == domain 3  score: 16.3 bits;  conditional E-value: 2.5e-06
  ANAPC4_WD40  37 edsevrsLaWkpdgk.lLav..aysdgevrlldaesgkvvhslsvksekavtclgWgen 92 
                  +   v+++aW+p  + lLa   +++d ++++ +  +g+++++l+++s+  v+ lgW++n
   EEA19104.1 440 HTAAVKAIAWSPHQHnLLASggGTADRTIKFWNTATGQLIRELDTGSQ--VCNLGWSKN 496
                  6678*******9887256654458999*******************99..******976 PP

  == domain 4  score: 3.1 bits;  conditional E-value: 0.034
  ANAPC4_WD40  27 qrvwtleedkedsevrsLaWkpdgklLavaysdgevrllda 67 
                  +++++l  +++  +v  La +pdg+ ++ +  d ++r+ ++
   EEA19104.1 520 EQIVSL--TGHTFRVLYLAISPDGQTIVTGAGDETLRFWKI 558
                  455555..678889999*****************9987655 PP

>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.5   0.0    0.0019       6.9      84     141 ..     297     354 ..     289     377 .. 0.70
   2 !   10.1   0.0   0.00015      0.53      66     140 ..     406     481 ..     388     488 .. 0.60
   3 !   13.3   0.0   1.5e-05     0.055      55     123 ..     481     552 ..     477     569 .. 0.79

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0019
                 EEEEEECS...CEEEEEEEEES--EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEE CS
       eIF2A  84 kvslfdlk...vkviskleeqkrNtiffspkgklvllaGfgnlaGeleiwdvkkkkkiaka 141
                 +v++++++   v  +++l+ +   ++ + ++g+ ++++  + l   ++iwd ++++ + ++
  EEA19104.1 297 SVYMWHSQsgqVTRLCELKDDTVTSVSWIQRGTHIAIGTGKGL---VQIWDAESCRRLRTM 354
                 5666666444477778888888888888888888888765544...888888888877665 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00015
                 EE-TTSS-EEEEESSSSCEEEEEEC.SCEEEEEEEEES-..-EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEE CS
       eIF2A  66 aWspkskefaviyGkmpakvslfdl.kvkviskleeqkr..NtiffspkgklvllaGfgnlaGeleiwdvkkkkkiak 140
                 +W+++  ++a   G  ++k  ++d+ +  ++++++++ +   +i +sp+++ +l +G g    ++++w++ + + i +
  EEA19104.1 406 KWNTEDGQLA--SGGNDNKLIVWDKlNETPLHRFSQHTAavKAIAWSPHQHNLLASGGGTADRTIKFWNTATGQLIRE 481
                 5555555543..566666666666545556666655543114666666666666666666666666666666555544 PP

  == domain 3  score: 13.3 bits;  conditional E-value: 1.5e-05
                 CEESSS.EEEEEE-TTSS-EEEEESSSSCEEEEEEC.SCEEEEEEEEES--EEE..E-TTSSEEEEE-TTSS CS
       eIF2A  55 elkkegpihdvaWspkskefaviyGkmpakvslfdl.kvkviskleeqkrNtif..fspkgklvllaGfgnl 123
                 el++  ++  + Ws++s+e++  +G++++++++++  ++++i++l  +    ++   sp g+ ++++   ++
  EEA19104.1 481 ELDTGSQVCNLGWSKNSDELISTHGYSQNQIVIWKYpRMEQIVSLTGHTFRVLYlaISPDGQTIVTGAGDET 552
                 67778889999************************978*******999888765226899999998754444 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       0.6   2.2e+03     188     214 ..     317     343 ..     285     347 .. 0.80
   2 ?   12.2   0.0   1.7e-05     0.062     180     223 ..     521     565 ..     496     569 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 0.6
    Ge1_WD40 188 sliveaafspdGtalatasedGevkff 214
                  ++++ ++   Gt +a+ +  G+v+ +
  EEA19104.1 317 DTVTSVSWIQRGTHIAIGTGKGLVQIW 343
                 357777888899999999999999988 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 1.7e-05
    Ge1_WD40 180 gllkieehs.liveaafspdGtalatasedGevkffqvyledeee 223
                  ++ ++ h+  +   a+spdG ++ t + d +++f++++ +++++
  EEA19104.1 521 QIVSLTGHTfRVLYLAISPDGQTIVTGAGDETLRFWKIFDVQNRN 565
                 567778888789999************************887765 PP

>> PALB2_WD40  Partner and localizer of BRCA2 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.2     0.052   1.9e+02     193     226 ..     289     322 ..     271     344 .. 0.65
   2 ?    8.2   0.1   0.00029         1     195     221 ..     461     487 ..     445     516 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.052
  PALB2_WD40 193 llgttvlnniviWnlktGqllkkieigesyqasv 226
                 +lg    n++ +W  ++Gq+ +  e+ +   +sv
  EEA19104.1 289 ILGVGLANSVYMWHSQSGQVTRLCELKDDTVTSV 322
                 5566666666666666666666655555555554 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.00029
  PALB2_WD40 195 gttvlnniviWnlktGqllkkieiges 221
                 g t++  i  Wn +tGql+++++ g+ 
  EEA19104.1 461 GGTADRTIKFWNTATGQLIRELDTGSQ 487
                 5799999**************998865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (580 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       330  (0.0184059); expected 358.6 (0.02)
Passed bias filter:                      254  (0.014167); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.48
# Mc/sec: 3630.96
//
Query:       EEA19105.1  [L=578]
Description: cell cycle regulatory protein (Srw1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    9.4e-25   86.4  11.5    2.5e-05   24.9   0.1    6.4  6  WD40         WD domain, G-beta repeat
    1.3e-14   54.2   5.8    0.00022   21.5   0.3    4.4  4  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
    7.2e-08   32.5   0.1      0.055   13.3   0.0    3.1  3  eIF2A        Eukaryotic translation initiation factor eIF2A
  ------ inclusion threshold ------
       0.02   13.9   0.0      0.062   12.3   0.0    1.8  2  Ge1_WD40     WD40 region of Ge1, enhancer of mRNA-decapping p
       0.17   10.7   1.1          1    8.2   0.1    2.2  2  PALB2_WD40   Partner and localizer of BRCA2 WD40 domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.8   0.6   0.00089       3.2      12      38 .]     315     342 ..     299     342 .. 0.85
   2 !    8.2   0.0    0.0013       4.7       4      34 ..     349     378 ..     346     379 .. 0.84
   3 !   19.7   0.0   3.2e-07    0.0011       2      38 .]     388     425 ..     387     425 .. 0.89
   4 !   24.9   0.1     7e-09   2.5e-05       2      38 .]     430     470 ..     429     470 .. 0.84
   5 ?    4.9   0.1     0.015        55       2      38 .]     475     513 ..     474     513 .. 0.76
   6 !   22.2   0.0   5.2e-08   0.00019       4      38 .]     520     555 ..     517     555 .. 0.88

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00089
                 S.EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  12 s.vtslafspdgawlasGsdDgtvriWd 38 
                 + vts+++ + g+ +a G+ +g v iWd
  EEA19105.1 315 DtVTSVSWIQRGTHIAIGTGKGLVQIWD 342
                 1599**9***********66*******9 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.0013
                 EEEEESS.SSEEEEEEETTSSE....EEEEETTSEE CS
        WD40   4 lrtltGH.ssvtslafspdgaw....lasGsdDgtv 34 
                 lrt  GH + v +l      aw    l+sG++D+ +
  EEA19105.1 349 LRTMIGHhNRVGAL------AWnehiLTSGGRDRLI 378
                 89999**999****......7777768899*9*976 PP

  == domain 3  score: 19.7 bits;  conditional E-value: 3.2e-07
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 q lr l GH + v++l+++ +   lasG+ D+++ +Wd
  EEA19105.1 388 QYLRRLAGHkQEVCGLKWNTEDGQLASGGNDNKLIVWD 425
                 5688999**777****999999999************9 PP

  == domain 4  score: 24.9 bits;  conditional E-value: 7e-09
                 EEEEEEESS.SSEEEEEEETTSSEEE.EEE..TTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawla.sGs..dDgtvriWd 38 
                 ++l+ ++ H   v ++a+sp+++ l+ sG+   D+t+++W+
  EEA19105.1 430 TPLHRFSQHtAAVKAIAWSPHQHNLLaSGGgtADRTIKFWN 470
                 689******777************752664447*******8 PP

  == domain 5  score: 4.9 bits;  conditional E-value: 0.015
                 EEEEEEESSSSEEEEEEETTSSEEEEE...ETTSEEEEEE CS
        WD40   2 qclrtltGHssvtslafspdgawlasG...sdDgtvriWd 38 
                 q++r+l++ s v+ l +s++++ l+s    s  + + iW+
  EEA19105.1 475 QLIRELDTGSQVCNLGWSKNSDELISThgyS-QNQIVIWK 513
                 6677775334699999*********953234.*******5 PP

  == domain 6  score: 22.2 bits;  conditional E-value: 5.2e-08
                 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 + +ltGH + v  la spdg+ +++G  D t+r+W+
  EEA19105.1 520 IVSLTGHtFRVLYLAISPDGQTIVTGAGDETLRFWK 555
                 6689***666****************66*******6 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.3   6.1e-08   0.00022      36      91 ..     312     366 ..     286     367 .. 0.88
   2 !   20.4   0.1   1.3e-07   0.00048      36      90 ..     395     448 ..     383     450 .. 0.93
   3 !   16.3   0.1   2.5e-06    0.0088      37      92 .]     438     494 ..     436     494 .. 0.85
   4 ?    3.1   0.0     0.034   1.2e+02      27      67 ..     518     556 ..     497     571 .. 0.77

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 6.1e-08
  ANAPC4_WD40  36 kedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgWge 91 
                   +d +v+s++W + g+ +a+++ +g v++ daes + ++++  +++ +v  l W+e
   EEA19105.1 312 LKDDTVTSVSWIQRGTHIAIGTGKGLVQIWDAESCRRLRTMIGHHN-RVGALAWNE 366
                  57899***********************************987777.7******97 PP

  == domain 2  score: 20.4 bits;  conditional E-value: 1.3e-07
  ANAPC4_WD40  36 kedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgWg 90 
                  ++++ev +L+W+ ++  La + +d+++ + d  +++ +h +s ++  av+ + W+
   EEA19105.1 395 GHKQEVCGLKWNTEDGQLASGGNDNKLIVWDKLNETPLHRFSQHTA-AVKAIAWS 448
                  6799***************************************999.6******7 PP

  == domain 3  score: 16.3 bits;  conditional E-value: 2.5e-06
  ANAPC4_WD40  37 edsevrsLaWkpdgk.lLav..aysdgevrlldaesgkvvhslsvksekavtclgWgen 92 
                  +   v+++aW+p  + lLa   +++d ++++ +  +g+++++l+++s+  v+ lgW++n
   EEA19105.1 438 HTAAVKAIAWSPHQHnLLASggGTADRTIKFWNTATGQLIRELDTGSQ--VCNLGWSKN 494
                  6678*******9887256654458999*******************99..******976 PP

  == domain 4  score: 3.1 bits;  conditional E-value: 0.034
  ANAPC4_WD40  27 qrvwtleedkedsevrsLaWkpdgklLavaysdgevrllda 67 
                  +++++l  +++  +v  La +pdg+ ++ +  d ++r+ ++
   EEA19105.1 518 EQIVSL--TGHTFRVLYLAISPDGQTIVTGAGDETLRFWKI 556
                  455555..678889999*****************9987655 PP

>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.5   0.0    0.0019       6.8      84     141 ..     295     352 ..     287     375 .. 0.70
   2 !   10.1   0.0   0.00015      0.54      66     140 ..     404     479 ..     389     486 .. 0.58
   3 !   13.3   0.0   1.5e-05     0.055      55     123 ..     479     550 ..     475     567 .. 0.79

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0019
                 EEEEEECS...CEEEEEEEEES--EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEE CS
       eIF2A  84 kvslfdlk...vkviskleeqkrNtiffspkgklvllaGfgnlaGeleiwdvkkkkkiaka 141
                 +v++++++   v  +++l+ +   ++ + ++g+ ++++  + l   ++iwd ++++ + ++
  EEA19105.1 295 SVYMWHSQsgqVTRLCELKDDTVTSVSWIQRGTHIAIGTGKGL---VQIWDAESCRRLRTM 352
                 5666666444477778888888888888888888888765544...888888888877665 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00015
                 EE-TTSS-EEEEESSSSCEEEEEEC.SCEEEEEEEEES-..-EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEE CS
       eIF2A  66 aWspkskefaviyGkmpakvslfdl.kvkviskleeqkr..NtiffspkgklvllaGfgnlaGeleiwdvkkkkkiak 140
                 +W+++  ++a   G  ++k  ++d+ +  ++++++++ +   +i +sp+++ +l +G g    ++++w++ + + i +
  EEA19105.1 404 KWNTEDGQLA--SGGNDNKLIVWDKlNETPLHRFSQHTAavKAIAWSPHQHNLLASGGGTADRTIKFWNTATGQLIRE 479
                 5555555543..555566666665545556666655543114566666666666666666666666666665555544 PP

  == domain 3  score: 13.3 bits;  conditional E-value: 1.5e-05
                 CEESSS.EEEEEE-TTSS-EEEEESSSSCEEEEEEC.SCEEEEEEEEES--EEE..E-TTSSEEEEE-TTSS CS
       eIF2A  55 elkkegpihdvaWspkskefaviyGkmpakvslfdl.kvkviskleeqkrNtif..fspkgklvllaGfgnl 123
                 el++  ++  + Ws++s+e++  +G++++++++++  ++++i++l  +    ++   sp g+ ++++   ++
  EEA19105.1 479 ELDTGSQVCNLGWSKNSDELISTHGYSQNQIVIWKYpRMEQIVSLTGHTFRVLYlaISPDGQTIVTGAGDET 550
                 67778889999************************978*******999888765226899999998754444 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       0.6   2.1e+03     188     214 ..     315     341 ..     283     345 .. 0.80
   2 ?   12.3   0.0   1.7e-05     0.062     180     223 ..     519     563 ..     494     567 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 0.6
    Ge1_WD40 188 sliveaafspdGtalatasedGevkff 214
                  ++++ ++   Gt +a+ +  G+v+ +
  EEA19105.1 315 DTVTSVSWIQRGTHIAIGTGKGLVQIW 341
                 357777888899999999999999988 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 1.7e-05
    Ge1_WD40 180 gllkieehs.liveaafspdGtalatasedGevkffqvyledeee 223
                  ++ ++ h+  +   a+spdG ++ t + d +++f++++ +++++
  EEA19105.1 519 QIVSLTGHTfRVLYLAISPDGQTIVTGAGDETLRFWKIFDVQNRN 563
                 567778888789999************************887765 PP

>> PALB2_WD40  Partner and localizer of BRCA2 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.2     0.052   1.9e+02     193     226 ..     287     320 ..     269     342 .. 0.65
   2 ?    8.2   0.1   0.00029         1     195     221 ..     459     485 ..     443     514 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.052
  PALB2_WD40 193 llgttvlnniviWnlktGqllkkieigesyqasv 226
                 +lg    n++ +W  ++Gq+ +  e+ +   +sv
  EEA19105.1 287 ILGVGLANSVYMWHSQSGQVTRLCELKDDTVTSV 320
                 5566666666666666666666655555555554 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.00029
  PALB2_WD40 195 gttvlnniviWnlktGqllkkieiges 221
                 g t++  i  Wn +tGql+++++ g+ 
  EEA19105.1 459 GGTADRTIKFWNTATGQLIRELDTGSQ 485
                 5799999**************998865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (578 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       321  (0.017904); expected 358.6 (0.02)
Passed bias filter:                      247  (0.0137766); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.60u 0.31s 00:00:00.90 Elapsed: 00:00:00.50
# Mc/sec: 3477.19
//
Query:       EEA19106.1  [L=296]
Description: pyruvate dehydrogenase complex component Pdx1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      5e-07   29.9   0.0    1.4e-06   28.5   0.0    1.8  1  E3_binding  e3 binding domain


Domain annotation for each model (and alignments):
>> E3_binding  e3 binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.5   0.0     8e-11   1.4e-06       2      36 .]      40      77 ..      40      77 .. 0.92

  Alignments for each domain:
  == domain 1  score: 28.5 bits;  conditional E-value: 8e-11
                BE-HHHHHHHHHCT-...-TTTS---CTTTBE-HHHHC CS
  E3_binding  2 lAsPaaRklAkelGi...dLsdvkGtGpgGRItkeDVl 36
                +++P+++ l   +Gi   ++ ++++tGp+GR++k+DVl
  EEA19106.1 40 PLYPSVSQLLLLKGIpdsEIFKIPATGPKGRLLKGDVL 77
                589************87777799**************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (296 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       270  (0.0150594); expected 358.6 (0.02)
Passed bias filter:                      239  (0.0133304); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.47
# Mc/sec: 1880.55
//
Query:       EEA19107.1  [L=284]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00067   19.7   0.1     0.0018   18.3   0.1    1.8  1  CcmD      Heme exporter protein D (CcmD)


Domain annotation for each model (and alignments):
>> CcmD  Heme exporter protein D (CcmD)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.1     1e-07    0.0018       6      37 ..     103     134 ..     102     139 .. 0.94

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 1e-07
        CcmD   6 YVWlsYgitllvlagLilwslrdrrrllrelr 37 
                 YV ++Ygi++++++  ++ s +d++ +++ l+
  EEA19107.1 103 YVTGAYGIAAFAFGYAVINSSLDYQDTRANLA 134
                 ****************************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (284 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       550  (0.0306766); expected 358.6 (0.02)
Passed bias filter:                      386  (0.0215294); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 1895.11
//
Query:       EEA19108.1  [L=284]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00067   19.7   0.1     0.0018   18.3   0.1    1.8  1  CcmD      Heme exporter protein D (CcmD)


Domain annotation for each model (and alignments):
>> CcmD  Heme exporter protein D (CcmD)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.1     1e-07    0.0018       6      37 ..     103     134 ..     102     139 .. 0.94

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 1e-07
        CcmD   6 YVWlsYgitllvlagLilwslrdrrrllrelr 37 
                 YV ++Ygi++++++  ++ s +d++ +++ l+
  EEA19108.1 103 YVTGAYGIAAFAFGYAVINSSLDYQDTRANLA 134
                 ****************************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (284 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       550  (0.0306766); expected 358.6 (0.02)
Passed bias filter:                      386  (0.0215294); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 1963.13
//
Query:       EEA19109.1  [L=1265]
Description: cohesin complex subunit (Psm1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.8e-59  199.8   0.1      1e-57  195.2   0.1    2.3  1  SMC_N         RecF/RecN/SMC N terminal domain
    5.1e-31  107.4   0.0      2e-30  105.5   0.0    2.1  1  SMC_hinge     SMC proteins Flexible Hinge Domain
    9.8e-11   42.0  15.3    2.7e-05   24.1   0.0    4.3  3  AAA_21        AAA domain, putative AbiEii toxin, Type IV TA s
    5.6e-09   36.8  23.5    5.6e-09   36.8  23.5    6.4  4  AAA_23        AAA domain
    3.9e-08   32.9   0.0    9.6e-08   31.7   0.0    1.6  1  AAA_29        P-loop containing region of AAA domain
     0.0023   18.1   7.1       0.01   16.0   7.1    2.3  1  GFD1          GFD1 mRNA transport factor
     0.0029   17.8   0.0      0.018   15.2   0.0    2.5  1  SbcCD_C       Putative exonuclease SbcCD, C subunit
  ------ inclusion threshold ------
      0.011   15.5   2.5      0.013   15.2   0.7    2.1  2  TMP_2         Prophage tail length tape measure protein
       0.96   10.0   0.0       0.96   10.0   0.0    6.4  4  ABC_tran      ABC transporter
        1.8    8.6  60.4      0.047   13.7   5.3    8.4  9  DUF1664       Protein of unknown function (DUF1664)
        2.4    8.6   4.7         13    6.3   0.1    3.6  3  DUF2939       Protein of unknown function (DUF2939)
        4.1    5.5  89.9       0.01   14.1   6.8    4.1  4  FPP           Filament-like plant protein, long coiled-coil
        8.8    5.9  68.8         34    4.0   0.6    4.8  3  AAA_15        AAA ATPase domain
        9.1    5.8  99.0       0.18   11.4   3.1    7.0  6  Filament      Intermediate filament protein


Domain annotation for each model (and alignments):
>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  195.2   0.1   7.8e-61     1e-57       2     217 ..       4    1251 ..       3    1254 .. 0.97

  Alignments for each domain:
  == domain 1  score: 195.2 bits;  conditional E-value: 7.8e-61
                  EEEEEEESETTEECEEEEEETTSSEEEEEESTTSSHHHHHHHHHHHCTT.TTTTTTCHCCCCCC--............BTTCSSTTEEEEEEEE... CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............xxxxxxxxxxxxxxxx... RF
       SMC_N    2 lkrleienFksyagktvilpfsksftaivGpNGSGKsnlldAilFvLGersakklrseklsdlihk............skekasvkkaeveitf... 83  
                  l rle+ nFksy+g++v l  +  ft+i+GpNGSGKsn +dAi+FvLG +s+ +lrs++l+dl+++                    +a+        
  EEA19109.1    4 LVRLELFNFKSYKGHHVLLFGDAYFTSIIGPNGSGKSNSMDAISFVLGIKSS-HLRSTNLKDLVYRgrvlrtskvngdG-------SATAP--Eqng 90  
                  679*********************************************9888.************98775533322221.......22222..1223 PP

                  ...EETTEE...........................SSSSSSCEEEEEEEETTSEEEEEETTEEE-HHHHHHHHHCTT-STT............... CS
                  ...xxxxxx...........................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............... RF
       SMC_N   84 ...dnedkk...........................lkiekeevsisrrvkrkgeseykingkevtkkevsellesagiske............... 135 
                     +    +                           +    ee + +r++ ++g sey+in+k vt ++++e le ++i ++               
  EEA19109.1   91 nadE----AqdgsdvedsqtqgdrgdprsawvmavyEDDAGEEQQWKRSITSGGVSEYRINNKIVTAQQYNEALEAENILIKarnflvfqgdveaia 183 
                  3330....13334444555668889999**999876566668899**************************************************** PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19109.1  184 sqspkdltrlieqisgsleykveyerlkaeqeeaaeqqtfqlnrrrginseikqyqeqkreaenyarkaeerdqaiithilwklfhfqrlidessae 280 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19109.1  281 iqkhqdelkeyrrgvekyeknleeakkehakmgrevsnaernivkkerdiedatnslvpidekieitsgkvqryssriseitkerdtqtanvtrlek 377 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19109.1  378 dlkvvgkaqaeweaewaksmskaggqlseadlqeynklkeevnksssaeqlkldnlrrqkktdaetvnglkskfenaqwqlqsfetetktlktrktd 474 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19109.1  475 iantikdtsaeidrkkkelnavtserlrvsqmrtemeeklqlvlkklleaddgrkqsekeirmkemistlkrifpgvkgrvsdlcqpkqkkyaeavs 571 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19109.1  572 tvlgrhfdaivvdnektakeciqhlrdqragqatfipletiqvkafnsnlkgmhrgmrpaietvdyensvsraisyacgnaivcddldtakylcyek 668 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19109.1  669 gvdakavtldgtvihkgglmtggrgpgqqsskrwddselenlhklkdklladlaalpkghrrgtdeetlqgelvgleqrlayakeeskalerniksk 765 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19109.1  766 dselqfakkqvaevqpklrekekalkqlensissaeqsvagvedeiygdfcerlgydsirdyealqgslqeeasrkklefttqksrienqlsfekqr 862 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19109.1  863 lqatddrinslkaqykrdeaqimefkaeqdkirnkmdeleaeleilkerleeqkelyaesqeklsaqrrelqkrsknvedtlravnalegdiqrnss 959 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19109.1  960 nryallrrckledidlpladdsapldnlpidelvqtadedamdldedttmtgfeapgvqdygievdfdslgetlkesaedkleeelqdrirslntel 1056
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19109.1 1057 dkmapntramerletvenklrstekdfedarkrarkakedfedvmtqrselfnkafshiseqigpiyreltrsanyplggqayldiedsdepyldgi 1153
                  ************************************************************************************************* PP

                  ...............CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTT.SEEEEE-SSHHHCCC-SCEEEEEEEET CS
                  ...............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  136 ...............lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkekskn.aQfivislreemlekadklvgvtkven 216 
                                  LSgGekt++alaLlfA+++++p+p+++lDe+daaLD++nv+++a++++ +    +Qfivisl++++++ +++lvg++  + 
  EEA19109.1 1154 kyhampplkrfrdmeHLSGGEKTMAALALLFAVHSYQPSPFFVLDEVDAALDNTNVARIANYIRDHAAPgMQFIVISLKTGLFQLSEALVGIYRDQT 1250
                  ****************************************************************888777***********************9665 PP

                  T CS
                  x RF
       SMC_N  217 g 217 
                  +
  EEA19109.1 1251 E 1251
                  4 PP

>> SMC_hinge  SMC proteins Flexible Hinge Domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  105.5   0.0   1.5e-33     2e-30       2     116 ..     549     664 ..     548     665 .. 0.96

  Alignments for each domain:
  == domain 1  score: 105.5 bits;  conditional E-value: 1.5e-33
   SMC_hinge   2 kgvlGrladlievd.egyekAveaalgnrlqalvvedeetakkiieflkkknagratflpldrikqknkadgandknsgavplidlvevddelrkalry 99 
                 +gv Gr+ dl++++ ++y  Av+++lg + +a+vv++e+tak++i++l++++ag+atf+pl++i+ k  ++  +  ++g++p+i+ v++++++++a+ y
  EEA19109.1 549 PGVKGRVSDLCQPKqKKYAEAVSTVLGRHFDAIVVDNEKTAKECIQHLRDQRAGQATFIPLETIQVKAFNSNLKGMHRGMRPAIETVDYENSVSRAISY 647
                 79*************************************************************999988888888888********************* PP

   SMC_hinge 100 llgdtlvvdsldeAeel 116
                 ++g+ +v+d+ld+A+ l
  EEA19109.1 648 ACGNAIVCDDLDTAKYL 664
                 **************976 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.0   2.1e-08   2.7e-05       1      34 [.      28      62 ..      28     115 .. 0.79
   2 ?   -1.4   0.4       1.3   1.6e+03      95     164 ..     423     492 ..     403     542 .. 0.72
   3 !   19.8   5.6   4.3e-07   0.00055     219     296 ..    1040    1230 ..     788    1230 .. 0.67

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 2.1e-08
      AAA_21  1 lnvliGpNgsGKSnLLdaldllarl.drdvegltd 34
                ++ +iGpNgsGKSn +da++++ ++  +++++++ 
  EEA19109.1 28 FTSIIGPNGSGKSNSMDAISFVLGIkSSHLRSTNL 62
                789*******************9988444444443 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 1.3
      AAA_21  95 esgllldkrsleeedvfnpeargirggvsvfslkelsvsepndlqfgkaltditsrawsllllldglrke 164
                 +s + l+ ++l++ +++++e  +  + ++++ +++l   e +++  + + tdi +++ ++  + d   ke
  EEA19109.1 423 SSAEQLKLDNLRRQKKTDAETVNGLKSKFENAQWQLQSFETETKTLKTRKTDIANTIKDTSAEIDRKKKE 492
                 5566678889999999999999999999999999999999999999999999999998877777655433 PP

  == domain 3  score: 19.8 bits;  conditional E-value: 4.3e-07
      AAA_21  219 r................................................................................................ 219 
                  +                                                                                                
  EEA19109.1 1040 Kleeelqdrirslnteldkmapntramerletvenklrstekdfedarkrarkakedfedvmtqrselfnkafshiseqigpiyreltrsanyplgg 1136
                  0333333333333333333333333333333333333333444444444444444444444444555555555555555555555555556667777 PP

      AAA_21  220 ................gvvflengdgqelparelSdGtkrll..alltallralkkgsllliDEpEngLHPkllrrllellkelsrngaQviltT 296 
                                    ++  ++  + +++ +lS G k ++  all a+++  ++ +++++DE+++ L+   ++r++  ++++++ g Q+i+ +
  EEA19109.1 1137 qayldiedsdepyldgIKYHAMPPLKRFRDMEHLSGGEKTMAalALLFAVHSYQPS-PFFVLDEVDAALDNTNVARIANYIRDHAAPGMQFIVIS 1230
                  777777777777788788888889999999***********766888888888888.*****************************9****9976 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.8  23.5   4.4e-12   5.6e-09       1     200 []       6     303 ..       6     337 .. 0.54
   2 !    9.3   2.7    0.0011       1.4     146     197 ..     746     802 ..     673     805 .. 0.69
   3 ?    3.9  17.3     0.052        67      92     189 ..     836     941 ..     811     955 .. 0.44
   4 ?    3.7   2.1     0.061        79     115     175 ..    1035    1096 ..     986    1126 .. 0.56

  Alignments for each domain:
  == domain 1  score: 36.8 bits;  conditional E-value: 4.4e-12
      AAA_23   1 kLkienfrsfrdqe.idF.skgltlItGpNGaGKTTildAiklaLygetprlsrks.......grgfeksdveiese...................... 68 
                 +L++ nf+s+++ + + F +  +t I+GpNG+GK+  +dAi ++L+ +++ l++++       gr + +s+v+   +                      
  EEA19109.1   6 RLELFNFKSYKGHHvLLFgDAYFTSIIGPNGSGKSNSMDAISFVLGIKSSHLRSTNlkdlvyrGRVLRTSKVNGDGSatapeqngnadeaqdgsdveds 104
                 79999*****98884677888*********************************999888887334444444422224444444444333333333333 PP

      AAA_23  69 ......gkvkay.veltfenkdgry.....................................trsiererelskkkgkttkkaklellei......... 114
                       g+ ++  v   +e++ g++                                                                +         
  EEA19109.1 105 qtqgdrGDPRSAwVMAVYEDDAGEEqqwkrsitsggvseyrinnkivtaqqynealeaenilI--------------------------Karnflvfqg 177
                 334443222222344445555554477766666555553444333333333322222222220..........................1223333333 PP

      AAA_23 115 ..........deleqfisellgskkiilnlilflgqerfeefelkdkke.......rleelekeleeledekkllekl..................... 175
                           ++l+++i+++ gs +   ++  ++++++++ +++  +++       ++++++++++e+e+ +++ e++                     
  EEA19109.1 178 dveaiasqspKDLTRLIEQISGSLEYKVEYERLKAEQEEAAEQQTFQLNrrrginsEIKQYQEQKREAENYARKAEERdqaiithilwklfhfqrlide 276
                 444444455566666666655555555555555555553333333333322223334444444444444433333333566666666666666666665 PP

      AAA_23 176 ..eqekekekeleeleeeleeilkele 200
                    ++++ ++el+e ++  e+++k+le
  EEA19109.1 277 ssAEIQKHQDELKEYRRGVEKYEKNLE 303
                 553333333344444444444444433 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.0011
      AAA_23 146 felkdkkerleelekeleeledekkllekl.....eqekekekeleeleeeleeilk 197
                 ++l+  ke+ ++le+ ++ +  e ++ +k+      ++ ekek+l++le+ + ++++
  EEA19109.1 746 QRLAYAKEESKALERNIKSKDSELQFAKKQvaevqPKLREKEKALKQLENSISSAEQ 802
                 223444568888899998888888888888888865888999999999999998887 PP

  == domain 3  score: 3.9 bits;  conditional E-value: 0.052
      AAA_23  92 rerelskkkgkttkkaklellei.deleqfisellgskki.....ilnlilflgqerfeefelkdkkerleelekeleeledekkllekl..eqekeke 182
                 +e +++k +  t+k  ++++l+  +++ q +++ ++s k+     + ++  f++++++ +++  + + +le l++ lee+++   + +++   q+ e +
  EEA19109.1 836 EEASRKKLEFTTQKSRIENQLSFeKQRLQATDDRINSLKAqykrdEAQIMEFKAEQDKIRNKMDELEAELEILKERLEEQKELYAESQEKlsAQRRELQ 934
                 333333333333333333333333222233333222222222232334444444444433333333444444444444444433222222233444444 PP

      AAA_23 183 keleele 189
                 k+ +++e
  EEA19109.1 935 KRSKNVE 941
                 4444444 PP

  == domain 4  score: 3.7 bits;  conditional E-value: 0.061
      AAA_23  115 deleqfisellgskkiil..nlilflgqerfeefelkdkkerleelekeleeledekkllekl 175 
                  +  e++++e+l+ + ++l  +l  + +  r+ +++l++ +++l++ ek++e++ +++++ ++ 
  EEA19109.1 1035 ESAEDKLEEELQDRIRSLntELDKMAPNTRA-MERLETVENKLRSTEKDFEDARKRARKAKED 1096
                  2233344444443333332233333333332.4444444444444444444444444443333 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.7   0.0   7.5e-11   9.6e-08       1      46 [.       4      50 ..       4      58 .. 0.90

  Alignments for each domain:
  == domain 1  score: 31.7 bits;  conditional E-value: 7.5e-11
      AAA_29  1 LkrlqlvNWgtfdg.htieidlkgatlltGpsGsGKSTllDAiqalL 46
                L rl+l+N  +++g h++ +  + +t ++Gp+GsGKS  +DAi+++L
  EEA19109.1  4 LVRLELFNFKSYKGhHVLLFGDAYFTSIIGPNGSGKSNSMDAISFVL 50
                789***********8888888666*********************99 PP

>> GFD1  GFD1 mRNA transport factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   7.1     8e-06      0.01       2      20 ..     905     923 ..     905     925 .. 0.92

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 8e-06
        GFD1   2 lelLKKKIEEQrkIleekq 20 
                 le+LK+++EEQ+++++e+q
  EEA19109.1 905 LEILKERLEEQKELYAESQ 923
                 69***************99 PP

>> SbcCD_C  Putative exonuclease SbcCD, C subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   1.4e-05     0.018      28      89 ..    1165    1217 ..    1159    1218 .. 0.85

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1.4e-05
     SbcCD_C   28 rssgtlSGGekqflaylalaaalaalyssaegrepalrlvfLDEAFsklDeesiatllelle 89  
                  r+++ lSGGek ++a+lal++a++++  s         +++LDE  + lD++++a++ ++++
  EEA19109.1 1165 RDMEHLSGGEK-TMAALALLFAVHSYQPS--------PFFVLDEVDAALDNTNVARIANYIR 1217
                  68899******.88999988888765555........499***************9999876 PP

>> TMP_2  Prophage tail length tape measure protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   0.7     1e-05     0.013      89     194 ..     325     431 ..     317     438 .. 0.84
   2 ?   -2.4   0.0       2.5   3.2e+03     164     191 ..    1072    1099 ..    1052    1115 .. 0.64

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1e-05
       TMP_2  89 kgakearefnkaliltGnaaGlTasqLeamaesiaeaggtqaaaaealaalas.tGkiggeqlervakaaaelekatGqsvdetakelaklakdPvkaa 186
                 k +   ++ +++l+ + +++  T++++++++++i+e+++ + +  + ++ l +   ++g++q e  a+ a++++ka Gq  ++  +e++kl+++  k +
  EEA19109.1 325 KKERDIEDATNSLVPIDEKIEITSGKVQRYSSRISEITKERDTQTANVTRLEKdLKVVGKAQAEWEAEWAKSMSKAGGQLSEADLQEYNKLKEEVNKSS 423
                 667788999******************************555555555566551567889999999****************************99988 PP

       TMP_2 187 eklneqlh 194
                 ++ + +l 
  EEA19109.1 424 SAEQLKLD 431
                 76655555 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 2.5
       TMP_2  164 tGqsvdetakelaklakdPvkaaeklne 191 
                  +  ++  t k+++++ k + ka e+ ++
  EEA19109.1 1072 VENKLRSTEKDFEDARKRARKAKEDFED 1099
                  4555556666666666666665555443 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00075      0.96      14      35 ..      29      50 ..      23     143 .. 0.81
   2 ?   -1.7   0.1         3   3.8e+03      70     102 ..     758     790 ..     728     821 .. 0.47
   3 ?    0.1   4.1      0.81     1e+03      53      96 ..     835     902 ..     811     961 .. 0.72
   4 ?    6.2   0.0     0.011        14      79     134 ..    1130    1199 ..    1030    1202 .. 0.54

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00075
                EEEEESTTSSHHHHHHHHTTSS CS
                xxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran 14 vaivGenGaGKStLlkllagll 35
                + i+G+nG+GKS  + +++  l
  EEA19109.1 29 TSIIGPNGSGKSNSMDAISFVL 50
                68**********9999998655 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 3
                 S-TTSBHHHH...HHHTCHHHHHHHSTTGGTTCBGE CS
                 xxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  70 lfpeltvren...esdeeiekalsklglkelkdtvv 102
                 l ++++ +++    ++++++++  kl+ ke   + +
  EEA19109.1 758 LERNIKSKDSelqFAKKQVAEVQPKLREKE---KAL 790
                 222222111133222222333333333222...122 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.81
                 -HHHCCHCEEEE-SS--S-TTSBHHHH........................HHHTCHHHHHHHSTTGG CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx........................xxxxxxxxxxxxxxxxx RF
    ABC_tran  53 eleslrkeigvlpqepqlfpeltvren........................esdeeiekalsklglke 96 
                 ++e +rk++++ +q++++ ++l+ +++                        e ++e +k+++k++  e
  EEA19109.1 835 QEEASRKKLEFTTQKSRIENQLSFEKQrlqatddrinslkaqykrdeaqimEFKAEQDKIRNKMDELE 902
                 67899999999999999999998877789977777777777766666666633333444444443333 PP

  == domain 4  score: 6.2 bits;  conditional E-value: 0.011
                  H............HHHTCHHHHHHHSTTGG..TTCBGESTTSGGS-HHHHHHHHHHHHHHHT....SSEEEEES CS
                  x............xxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxx RF
    ABC_tran   79 n............esdeeiekalsklglke..lkdtvvksspssLSgGqkqrvalarallkk....pkllllDE 134 
                               e+++e+  +l+ ++ +     ++   +++++LSgG+k + ala +++ +    +++++lDE
  EEA19109.1 1130 AnyplggqayldiEDSDEP--YLDGIKYHAmpPLKRF--RDMEHLSGGEKTMAALALLFAVHsyqpSPFFVLDE 1199
                  1355555555533222222..2222222221122222..4569************9988754111145666666 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   3.3    0.0014       1.8      50     119 ..     274     346 ..     269     351 .. 0.87
   2 ?    1.8   0.3      0.18   2.4e+02      77     124 .]     339     386 ..     328     386 .. 0.74
   3 ?    2.1   2.4      0.14   1.8e+02      52     115 ..     414     477 ..     391     485 .. 0.51
   4 ?    0.6   5.5      0.43   5.6e+02      63     120 ..     460     517 ..     431     521 .. 0.73
   5 ?    1.5   4.6      0.22   2.8e+02      39     120 ..     468     517 ..     456     560 .. 0.53
   6 ?    7.5   1.0    0.0032       4.1      56     117 ..     750     811 ..     734     813 .. 0.68
   7 ?    5.0   4.5     0.018        23      65     119 ..     860     914 ..     831     917 .. 0.83
   8 ?   13.7   5.3   3.7e-05     0.047      54     119 ..     891     956 ..     882     961 .. 0.93
   9 ?    6.5   1.1    0.0065       8.3      59     112 ..    1040    1092 ..    1023    1105 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0014
     DUF1664  50 leqvseslaatkrhLss...ridrvdkkldeqkeiskeikeevtevredlseigedvesvkeavegleskler 119
                 +++ s+++++ +++L++    +++ +k+l+e k+  +++ +ev+++++++ + ++d+e   +    +++k+e 
  EEA19109.1 274 IDESSAEIQKHQDELKEyrrGVEKYEKNLEEAKKEHAKMGREVSNAERNIVKKERDIEDATNSLVPIDEKIEI 346
                 6888999999999987532259999**********************************99999999999986 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.18
     DUF1664  77 eqkeiskeikeevtevredlseigedvesvkeaveglesklerieekQ 124
                    e ++ ++ +v++ ++ +sei ++ ++  + v+ le+ l+ + + Q
  EEA19109.1 339 PIDEKIEITSGKVQRYSSRISEITKERDTQTANVTRLEKDLKVVGKAQ 386
                 555666777888899999999999999999999999998888877665 PP

  == domain 3  score: 2.1 bits;  conditional E-value: 0.14
     DUF1664  52 qvseslaatkrhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeavegles 115
                 +++e++++     + ++d++ ++ +  +e+ + +k++ ++++ +l++++++ +++k+  +++++
  EEA19109.1 414 KLKEEVNKSSSAEQLKLDNLRRQKKTDAETVNGLKSKFENAQWQLQSFETETKTLKTRKTDIAN 477
                 3334444444444445555555555555555555555555555555555555555555555444 PP

  == domain 4  score: 0.6 bits;  conditional E-value: 0.43
     DUF1664  63 hLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeavegleskleri 120
                  ++ + +++ ++  + ++++k++++e+++ +++l+++ ++   v+++ +++e+kl+ +
  EEA19109.1 460 SFETETKTLKTRKTDIANTIKDTSAEIDRKKKELNAVTSERLRVSQMRTEMEEKLQLV 517
                 4455666777777778888888888888888888888888888888888888888765 PP

  == domain 5  score: 1.5 bits;  conditional E-value: 0.22
     DUF1664  39 lsdavesvskqleqvseslaatkrhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeavegleskleri 120
                 l+   +++++ +++ s+++ + k++L                                +++ ++   v+++ +++e+kl+ +
  EEA19109.1 468 LKTRKTDIANTIKDTSAEIDRKKKEL--------------------------------NAVTSERLRVSQMRTEMEEKLQLV 517
                 44444455555555555555555555................................444444444444444444444332 PP

  == domain 6  score: 7.5 bits;  conditional E-value: 0.0032
     DUF1664  56 slaatkrhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeavegleskl 117
                   ++  + L+++i++ d++l+  k+  +e++ ++ e ++ l+++++ ++s ++ v g+e ++
  EEA19109.1 750 YAKEESKALERNIKSKDSELQFAKKQVAEVQPKLREKEKALKQLENSISSAEQSVAGVEDEI 811
                 33344456777888888888888888888888888888888888888888888777777665 PP

  == domain 7  score: 5.0 bits;  conditional E-value: 0.018
     DUF1664  65 ssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeavegleskler 119
                 ++r++  d+++++ k+  k  +++++e + + ++i+++++++++  e l+++le+
  EEA19109.1 860 KQRLQATDDRINSLKAQYKRDEAQIMEFKAEQDKIRNKMDELEAELEILKERLEE 914
                 5899999999999999999999999999999999999999999999999988875 PP

  == domain 8  score: 13.7 bits;  conditional E-value: 3.7e-05
     DUF1664  54 seslaatkrhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeavegleskler 119
                 ++++++  ++L+++++ + ++l+eqke+ +e +e++++ r++l++ +++ve   +av+ le+ ++r
  EEA19109.1 891 QDKIRNKMDELEAELEILKERLEEQKELYAESQEKLSAQRRELQKRSKNVEDTLRAVNALEGDIQR 956
                 6899999*******************************************************9987 PP

  == domain 9  score: 6.5 bits;  conditional E-value: 0.0065
     DUF1664   59 atkrhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeaveg 112 
                  +  ++L++ri +++++ld+++  +++++  +++v+++l+++++d+e  ++  ++
  EEA19109.1 1040 KLEEELQDRIRSLNTELDKMAPNTRAME-RLETVENKLRSTEKDFEDARKRARK 1092
                  44579**************999998885.6999999999999999987776655 PP

>> DUF2939  Protein of unknown function (DUF2939)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.3       2.1   2.7e+03      36      65 ..     826     856 ..     825     900 .. 0.75
   2 ?    1.8   0.0      0.26   3.3e+02      35      59 ..    1024    1048 ..    1018    1069 .. 0.79
   3 ?    6.3   0.1    0.0099        13       2      35 ..    1183    1216 ..    1182    1220 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 2.1
     DUF2939  36 dfpalraslkaqlnaellraaapdke.ddpl 65 
                 d++al+ sl+++ +++ l+  +++ + +++l
  EEA19109.1 826 DYEALQGSLQEEASRKKLEFTTQKSRiENQL 856
                 7889999999988888765544444455555 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.26
     DUF2939   35 Vdfpalraslkaqlnaellraaapd 59  
                  Vdf++l ++lk++ +++l ++ +++
  EEA19109.1 1024 VDFDSLGETLKESAEDKLEEELQDR 1048
                  9************999997776554 PP

  == domain 3  score: 6.3 bits;  conditional E-value: 0.0099
     DUF2939    2 laalgayaasPylalyqlksAararDaaalselV 35  
                  l+a+  y  sP++ l+ +++A+++ ++a++++++
  EEA19109.1 1183 LFAVHSYQPSPFFVLDEVDAALDNTNVARIANYI 1216
                  677888889**********************998 PP

>> FPP  Filament-like plant protein, long coiled-coil
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0  37.6    0.0087        11     466     817 ..     181     530 ..      91     544 .. 0.69
   2 ?   14.1   6.8   8.1e-06      0.01     259     322 ..     735     798 ..     727     812 .. 0.87
   3 ?    2.2  21.1     0.031        40     692     814 ..     840     959 ..     813     975 .. 0.56
   4 ?    2.7   1.2     0.021        27     686     744 ..    1038    1095 ..     988    1120 .. 0.65

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.0087
         FPP 466 vilesrvkekslekiledirvalkevnees.aeasdslasseeeeedassdektlked.slevekeeevseeeksseeeskqkiqqelskaiskiielv 562
                 +i ++  + k+l +++e+i   l++  e +  +a      +ee +e+++ + +  +   ++e+++ +e+++e+ +++++ +++ q  +++ + k+ ++ 
  EEA19109.1 181 AIASQ--SPKDLTRLIEQISGSLEYKVEYErLKA-----EQEEAAEQQTFQLNRRR-GiNSEIKQYQEQKREAENYARKAEERDQAIITHILWKLFHFQ 271
                 44443..557778888888888875333221222.....22222223222222333.24777888888888888888888899999999999******* PP

         FPP 563 eslskealklqdkssksselsevleqFsavvndllsgkadledfvleLssvldeiselkfslldvssmeeeikksddi..dkvalsenkvaqk.gessn 658
                   ++++++++q+++ + +e ++ +e++ + ++   + k+++ ++  e+s++  +i++ + ++ d  ++   i ++ +i  +kv +  +++ +  +e+  
  EEA19109.1 272 RLIDESSAEIQKHQDELKEYRRGVEKYEKNLE---EAKKEHAKMGREVSNAERNIVKKERDIEDATNSLVPIDEKIEItsGKVQRYSSRISEItKERDT 367
                 **********9999988888888888876555...5577777888899999999999999999999998888777665225666666666444455566 PP

         FPP 659 ecaeisklssekeipselplvsgsnesk...keenkllkeeleelksekenlevelksatenleslkaqlqesEqllaelkseLeslkeskslaetqlk 754
                 ++a++ +l+++ ++  +     +++ +k   k+  +l++ +l+e +  ke+++ + + ++ +l++l  q +   ++++ lks++e+++   +  et+ k
  EEA19109.1 368 QTANVTRLEKDLKVVGKAQAEWEAEWAKsmsKAGGQLSEADLQEYNKLKEEVNKSSSAEQLKLDNLRRQKKTDAETVNGLKSKFENAQWQLQSFETETK 466
                 666666666666664444433332222244477888999999999999999999999999999999999999999999999999999998888888888 PP

         FPP 755 cmkesyesletrateleaelnelkqkieaLeveLeeekksheeleakcke.lqeqlervekkev 817
                   k+ + ++    ++  ae+ + k++++a+++e    +++  e e k +  l++ le    ++ 
  EEA19109.1 467 TLKTRKTDIANTIKDTSAEIDRKKKELNAVTSERLRVSQMRTEMEEKLQLvLKKLLEADDGRKQ 530
                 8887777777777777777777777777777776666666555555544213333333333333 PP

  == domain 2  score: 14.1 bits;  conditional E-value: 8.1e-06
         FPP 259 eklqkenefLterLlameeEtkmLKEaLakrnsELqaSrnmcAktaskLsqlEaqleelskqks 322
                 e+lq e   L +rL    eE k L   ++ ++sELq++++ +A +  kL++ E+ l++l+++ s
  EEA19109.1 735 ETLQGELVGLEQRLAYAKEESKALERNIKSKDSELQFAKKQVAEVQPKLREKEKALKQLENSIS 798
                 678888999************************************************9998843 PP

  == domain 3  score: 2.2 bits;  conditional E-value: 0.031
         FPP 692 llkeeleelkseken.l...evelksatenleslkaqlqesEqllaelkseLeslkeskslaetqlkcmkesyesletrateleaelnelkqkieaLev 786
                 ++k e++  ks+ en l   + +l+   ++++slkaq++  E ++ e k+e +++++    +e +l+    ++e le +++       e ++k++a   
  EEA19109.1 840 RKKLEFTTQKSRIENqLsfeKQRLQATDDRINSLKAQYKRDEAQIMEFKAEQDKIRNKMDELEAELEI---LKERLEEQKE----LYAESQEKLSAQRR 931
                 33333333333322211111234555555666666666666666666666666655555555554432...2333444333....34456666677777 PP

         FPP 787 eLeeekksheeleakckelqeqlervek 814
                 eL++++k+ e+++ +++ l+  ++r+++
  EEA19109.1 932 ELQKRSKNVEDTLRAVNALEGDIQRNSS 959
                 7777777777777777777777777765 PP

  == domain 4  score: 2.7 bits;  conditional E-value: 0.021
         FPP  686 kkeenkllkeeleelksekenlevelksatenleslkaqlqesEqllaelkseLeslke 744 
                  +++ ++ l++ +++l+ e ++++ +  +a e+le++ ++l+ +E+  ++ ++   ++ke
  EEA19109.1 1038 EDKLEEELQDRIRSLNTELDKMAPN-TRAMERLETVENKLRSTEKDFEDARKRARKAKE 1095
                  2344455566666666666666654.455667777777777777777777665554444 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8  39.3      0.03        39       2     275 ..       3     462 ..       3     569 .. 0.54
   2 ?    1.9  14.6      0.11   1.5e+02     117     288 ..     760     948 ..     732     986 .. 0.61
   3 ?    4.0   0.6     0.026        34     219     261 ..    1030    1088 ..    1016    1133 .. 0.50

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.03
      AAA_15   2 kIkkikikNFRslkdveidlsee..ltvliGkNnsGKSsilealdlFlnnkekkn............................................ 54 
                 k+ ++++ NF+s+k  ++ l  +  +t +iG+N+sGKS+ ++a+ + l  k+++                                             
  EEA19109.1   3 KLVRLELFNFKSYKGHHVLLFGDayFTSIIGPNGSGKSNSMDAISFVLGIKSSHLrstnlkdlvyrgrvlrtskvngdgsatapeqngnadeaqdgsdv 101
                 56788999*******7776655558************************9977779999********************************99999999 PP

      AAA_15  55 ....................................................................kkvikiekedleifeniseskdikIdvef.. 83 
                                                                                                                    
  EEA19109.1 102 edsqtqgdrgdprsawvmavyeddageeqqwkrsitsggvseyrinnkivtaqqynealeaenilikaR---------------------------Nfl 173
                 999999999999999999999999999999999999999886666333333333333333333333330...........................244 PP

      AAA_15  84 .....................................................................................aekekakeyektlk 97 
                                                                                                      +             
  EEA19109.1 174 vfqgdveaiasqspkdltrlieqisgsleykveyerlkaeqeeaaeqqtfqlnrrrginseikqyqeqkreaenyarkaeerdqaI------------- 259
                 55777777666666666666666666665555555555555555555555555555554444444433333222222111111110............. PP

      AAA_15  98 skekkkadlllkkkesdlkktikdkklklkknelsdekisvekkkskkelpkekeeklekekeelkidkedlkklikkleeslkkee............ 184
                  + + ++ + +++++++ +  i++++ +lk+++  +ek++ + +++kke+ k+ +e ++ e + +k++                               
  EEA19109.1 260 ITHILWKLFHFQRLIDESSAEIQKHQDELKEYRRGVEKYEKNLEEAKKEHAKMGREVSNAERNIVKKE------------------Rdiedatnslvpi 340
                 12222222233333333333333333333333333333333333333333333333333333333222..................1333333444444 PP

      AAA_15 185 ........elknvlksaiiklllisakRnvsdedsekkssllgklkekileealqekl..................eeelteklkeiqeklkeidkkla 257
                          + + ++s i ++    + ++++ ++ ek  ++ gk++ +   e +++ +                  +ee+++ ++  q kl+++  + +
  EEA19109.1 341 dekieitsGKVQRYSSRISEITKERDTQTANVTRLEKDLKVVGKAQAEWEAEWAKS-MskaggqlseadlqeynklKEEVNKSSSAEQLKLDNLRRQKK 438
                 44555555444444444555555555555555555555555555555544432222.234444444444444333333333333333333333333333 PP

      AAA_15 258 eelk......kilkkkidkikkfn 275
                 ++++      +++++   ++++f+
  EEA19109.1 439 TDAEtvnglkSKFENAQWQLQSFE 462
                 332233222222222222222222 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.11
      AAA_15 117 ktikdkklklkknelsdekisvekkkskkelpkekeeklekekeelkidkedlkklikkleeslkkee............................elk 187
                                            + + ++++  +++k+ +e++ +  +++k +k+le+s+++ e                            + +
  EEA19109.1 760 R--------------------------NIKSKDSELQFAKKQVAEVQPKLREKEKALKQLENSISSAEqsvagvedeiygdfcerlgydsirdyeaLQG 832
                 2..........................223333333444444444444455666666666666666666666666666666666667777888887666 PP

      AAA_15 188 nvlksaiiklllisakRnvsdedsekkssllgklkekileealqekleeelteklkeiqeklkeidkklaeelk.............kilkkkidkikk 273
                 ++ ++a++k l +  +++  +++   ++  l +++++i++ ++q k +e +++++k  q+k++++ ++l++el+              + ++k++    
  EEA19109.1 833 SLQEEASRKKLEFTTQKSRIENQLSFEKQRLQATDDRINSLKAQYKRDEAQIMEFKAEQDKIRNKMDELEAELEilkerleeqkelyAESQEKLSAQRR 931
                 666677777777777777777777777777777777777777777778888999999999999999999777776666665555455333333333334 PP

      AAA_15 274 fnykgkkneeieik..d 288
                 +  k++kn+e++++  +
  EEA19109.1 932 ELQKRSKNVEDTLRavN 948
                 44444444444444553 PP

  == domain 3  score: 4.0 bits;  conditional E-value: 0.026
      AAA_15  219 gklkekileealqekl................eeelteklkeiqeklkeidkklaeelk 261 
                  g+++++  e++l+e+l                + +  e l+ +++kl+ ++k++++  k
  EEA19109.1 1030 GETLKESAEDKLEEELqdrirslnteldkmapNTRAMERLETVENKLRSTEKDFEDARK 1088
                  33333333333222222222333333344444444444444444444444444443333 PP

>> Filament  Intermediate filament protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1  22.6      0.18   2.3e+02     145     265 ..     211     335 ..     188     354 .. 0.66
   2 ?    1.3   2.3      0.17   2.1e+02     203     278 ..     343     419 ..     334     425 .. 0.64
   3 ?    8.6  13.0     0.001       1.3     194     283 ..     427     515 ..     409     524 .. 0.87
   4 ?   11.4   3.1   0.00014      0.18     207     275 ..     744     808 ..     732     817 .. 0.77
   5 ?    6.3  18.3    0.0048       6.1     192     298 ..     844     953 ..     821     965 .. 0.64
   6 ?    2.3   4.4     0.082     1e+02     219     273 ..    1043    1103 ..    1023    1119 .. 0.55

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.18
                 XXXXXXXXXXXXXXXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXXXX-HHHHHHHHHHHHHHHHHHHHHHHH CS
    Filament 145 kelqkqvseqvlvevdaarkld..Lteilkeiraqyeelaeknreeaee...wykskleelqeaaeknsealrsakeeitelrrqiqsleieleslkkq 238
                 k  q++++eq + +++  r+++  +++  +e +++ e+ a+k +e  ++       kl + q+ ++++s+++++++ e++e+rr +++ e +le+ kk+
  EEA19109.1 211 KAEQEEAAEQQTFQLNRRRGINseIKQY-QEQKREAENYARKAEERDQAiitHILWKLFHFQRLIDESSAEIQKHQDELKEYRRGVEKYEKNLEEAKKE 308
                 3334444444444444444443225554.555555666655544433330003446889999************************************* PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Filament 239 kasleaqlaeleerleaeleklqekls 265
                 +a++ ++++++e ++ ++ ++++++ +
  EEA19109.1 309 HAKMGREVSNAERNIVKKERDIEDATN 335
                 ************998776666655544 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.17
                 XXXXXXXXXXX-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHH CS
    Filament 203 aaeknsealrsakeeitelrrqiqsleieleslkkqkasleaqlaeleerleaeleklqeklsele.eelaeireem 278
                 ++e  s ++++  + i+e+ ++ ++ ++++  l+k  + + ++ ae e++ ++ ++k+  +lse + +e ++++ee+
  EEA19109.1 343 KIEITSGKVQRYSSRISEITKERDTQTANVTRLEKDLKVVGKAQAEWEAEWAKSMSKAGGQLSEADlQEYNKLKEEV 419
                 45555566666667777777777777777777777777777777777777777777777777666634455555555 PP

  == domain 3  score: 8.6 bits;  conditional E-value: 0.001
                 XXXXXXXXXXXXXXXXXXXX-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Filament 194 kskleelqeaaeknsealrsakeeitelrrqiqsleieleslkkqkasleaqlaeleerleaeleklqeklseleeelaeireemarqlr 283
                 + kl++l+++ +++ e+++  k+  ++++ q+qs e+e + lk  k  + ++++++ ++++++ ++l++  se    ++++r em+ +l+
  EEA19109.1 427 QLKLDNLRRQKKTDAETVNGLKSKFENAQWQLQSFETETKTLKTRKTDIANTIKDTSAEIDRKKKELNAVTSER-LRVSQMRTEMEEKLQ 515
                 679**************************************************************999877665.679********9986 PP

  == domain 4  score: 11.4 bits;  conditional E-value: 0.00014
                 XXXXXXX-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Filament 207 nsealrsakeeitelrrqiqsleieleslkkqkasleaqlaeleerleaeleklqeklseleeelaeir 275
                  ++ l  akee + l r+i+s+ +el+  kkq a ++ +l+e e+     l++l++++s+ e+ +a + 
  EEA19109.1 744 LEQRLAYAKEESKALERNIKSKDSELQFAKKQVAEVQPKLREKEKA----LKQLENSISSAEQSVAGVE 808
                 56788899**********************************9875....4555555555555555544 PP

  == domain 5  score: 6.3 bits;  conditional E-value: 0.0048
                 XXXXXXXXXXXXXXXXXXXXXX-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Filament 192 wykskleelqeaaeknsealrsakeeitelrrqiqsleieleslkkqkasleaqlaeleerle...aeleklqeklseleeelaeireemarqlreYqe 287
                  + ++ ++++++ + +++ l+++   i+ l+ q ++ e+++ + k++++++++++ ele++le   + le+ +e  +e +e+l+  r+e++++ ++ ++
  EEA19109.1 844 EFTTQKSRIENQLSFEKQRLQATDDRINSLKAQYKRDEAQIMEFKAEQDKIRNKMDELEAELEilkERLEEQKELYAESQEKLSAQRRELQKRSKNVED 942
                 477777777777777777777777777777777777777777777777777777777776543221556666666777777777777777777766666 PP

                 HHHHHHHHHHH CS
    Filament 288 LLdvKlaLdiE 298
                  L    aL+  
  EEA19109.1 943 TLRAVNALEGD 953
                 66655555555 PP

  == domain 6  score: 2.3 bits;  conditional E-value: 0.082
                  HHHHHHHHHHHHHHHHHHHHH......HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Filament  219 telrrqiqsleieleslkkqk......asleaqlaeleerleaeleklqeklseleeelae 273 
                  +el+ +i sl++el+++  +       +++e++l+ +e+ +e ++++++++ ++ e+ +++
  EEA19109.1 1043 EELQDRIRSLNTELDKMAPNTramerlETVENKLRSTEKDFEDARKRARKAKEDFEDVMTQ 1103
                  3455566666666665543330000113345566666666666666666665555555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1265 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2804  (0.156395); expected 358.6 (0.02)
Passed bias filter:                      626  (0.0349155); expected 358.6 (0.02)
Passed Vit filter:                       208  (0.0116013); expected 17.9 (0.001)
Passed Fwd filter:                       123  (0.00686039); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 2.73u 0.43s 00:00:03.16 Elapsed: 00:00:00.67
# Mc/sec: 5667.42
//
Query:       EEA19110.1  [L=463]
Description: hypothetical protein PMAA_013730 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.4e-51  171.6   0.1    8.7e-51  171.2   0.1    1.2  1  DUF2841   Protein of unknown function (DUF2841)


Domain annotation for each model (and alignments):
>> DUF2841  Protein of unknown function (DUF2841)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  171.2   0.1   4.9e-55   8.7e-51       2     123 ..     136     271 ..     135     272 .. 0.98

  Alignments for each domain:
  == domain 1  score: 171.2 bits;  conditional E-value: 4.9e-55
     DUF2841   2 iedeeeveeyyerafkalqqlnckviakawikliepkkqvkypYngg..............ektkPeWWPkevrhkePdhlkkeerirLlvhilrelae 86 
                 ++de+++++yye+af+++qqlnc+viaka+ikl+ep+kqv+ypYng+              e+tkP+WWP +v+hkePdhl k+eri+Ll+hilrel+e
  EEA19110.1 136 VDDEARLKKYYEKAFDSFQQLNCRVIAKAFIKLVEPRKQVNYPYNGRrassspggerradpEMTKPPWWPVGVTHKEPDHLLKPERIQLLIHILRELGE 234
                 799************************************************************************************************ PP

     DUF2841  87 seeitvekLeeatkevkrqikpeerkeiLkeiykvak 123
                 s+++t+ekL++a+++v+r+i+p er++iL+e+y+v++
  EEA19110.1 235 SHDVTAEKLRDAGQDVRRSISPPERLQILDEVYSVRH 271
                 ***********************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (463 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      264  (0.0147247); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.24s 00:00:00.72 Elapsed: 00:00:00.40
# Mc/sec: 3462.76
//
Query:       EEA19111.1  [L=531]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-42  144.1   8.4    1.7e-42  144.1   8.4    2.3  2  DUF2838   Protein of unknown function (DUF2838)


Domain annotation for each model (and alignments):
>> DUF2838  Protein of unknown function (DUF2838)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  144.1   8.4   9.6e-47   1.7e-42       1     111 []     170     280 ..     170     280 .. 0.99
   2 !    2.7   3.1    0.0079   1.4e+02      10      54 ..     393     437 ..     378     441 .. 0.77

  Alignments for each domain:
  == domain 1  score: 144.1 bits;  conditional E-value: 9.6e-47
     DUF2838   1 dklsFvlgvlnvlltafllgaapellplvylvlllvllplryityrkkklhyfllDfCYfvnilllllllvlpeseklfkavfalanGplalAiilwrn 99 
                 +k+sF++gv+n++++++l+gaape ++++y+++l++++p+r++ y+k+++hyfl+D+CYfvn+l +l ++v+p+s++l + +++la+G+ a+Ai +wrn
  EEA19111.1 170 EKISFIAGVMNIFISGYLMGAAPERFYWWYTAQLVYFMPIRLYSYHKRGYHYFLADLCYFVNFLSMLSIWVFPKSKRLLIGTYCLAYGNNAVAIAMWRN 268
                 79************************************************************************************************* PP

     DUF2838 100 slvfhsldkvtS 111
                 slvfhs+dkv+S
  EEA19111.1 269 SLVFHSMDKVVS 280
                 **********97 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.0079
     DUF2838  10 lnvlltafllgaapellplvylvlllvllplryityrkkklhyfl 54 
                 +++  +  ll++ p  l+++y  ++ +++ + ++   +++  y++
  EEA19111.1 393 MMIQYVYALLTMIPCPLWFWYRWASSIFMLVVFVWSIHNGATYYI 437
                 445555667778888888888888888888888877777777775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (531 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       937  (0.0522617); expected 358.6 (0.02)
Passed bias filter:                      588  (0.032796); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.46
# Mc/sec: 3448.42
//
Query:       EEA19112.1  [L=560]
Description: MRS7 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   3.6e-104  347.8   0.1   3.6e-104  347.8   0.1    1.4  2  LETM1     LETM1-like protein
    0.00017   21.2   0.1       0.01   15.5   0.0    3.0  3  SAP       SAP domain
  ------ inclusion threshold ------
        2.4    7.2  12.1        1.6    7.7   0.1    2.3  2  BPL_N     Biotin-protein ligase, N terminal


Domain annotation for each model (and alignments):
>> LETM1  LETM1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  347.8   0.1  6.1e-108  3.6e-104       2     268 .]     158     421 ..     157     421 .. 0.97
   2 ?   -4.4   0.2       1.6   9.4e+03     103     217 ..     471     489 ..     463     497 .. 0.53

  Alignments for each domain:
  == domain 1  score: 347.8 bits;  conditional E-value: 6.1e-108
       LETM1   2 fpkikkelkhyvkGtkllfadvkisvkllvkllkgkeLsrrEreqlkrttaDllrlvPfsvfiivPfaelllpvllklFPnlLpstFeskkqkeeklkk 100
                  +kik+e++hy++Gtkll+++v+isvkl++k+++g+eLsrrE++ql+rt++Dl rlvPfsvf+ivPfaelllp++l++FPn+Lpst+e +k++++k++ 
  EEA19112.1 158 GQKIKHEIQHYWDGTKLLATEVRISVKLAMKMAAGYELSRRENRQLQRTVKDLARLVPFSVFVIVPFAELLLPIALRIFPNMLPSTYEGQKSRDKKAET 256
                 689************************************************************************************************ PP

       LETM1 101 rlkarlevakfLqetleeslkkkkkekkekaeelkeflkkvrsggepeevsneeilkvaklFkdeltLdnlsrkqlkalckllslqpfgtdnllryrlr 199
                  + +r+ev+ fL++tl+e+   + +++++k+ee++ef+kk+rs+g  e++s  +++kv k+Fkd+ltLdnlsr+ql+ +ck+++l++fgtd +lry +r
  EEA19112.1 257 LRGTRKEVSAFLKDTLKETG-LPLSAETAKKEEFTEFFKKLRSTG--ESPSDADVIKVIKIFKDDLTLDNLSRPQLVGMCKYMNLNSFGTDAMLRYTIR 352
                 ****************9983.455666789***************..789************************************************* PP

       LETM1 200 kklreikedDkaikreGvdsLseeeLqeacrsRGlraaglseeelreqLeqWlelslkkkvpsslLlLs 268
                 +++r+ik+dD+ai++eGvdsLs+ eLq ac+sRGlr++g+s+ +lr++L+ Wl+l+lk+ vps++L+Ls
  EEA19112.1 353 HRMRQIKRDDRAISYEGVDSLSVPELQIACASRGLRTHGVSPGRLRDDLSMWLDLRLKQGVPSTMLVLS 421
                 *******************************************************************97 PP

  == domain 2  score: -4.4 bits;  conditional E-value: 1.6
       LETM1 103 karlevakfLqetleeslkkkkkekkekaeelkeflkkvrsggepeevsneeilkvaklFkdeltLdnlsrkqlkalckllslqpfgtdnllryrlrkk 201
                 ++rlev+k  qe +ee                                                                                   
  EEA19112.1 471 RQRLEVIKEQQELIEEE---------------------------------------------------------------------------------- 487
                 44555555555555443.................................................................................. PP

       LETM1 202 lreikedDkaikreGv 217
                                 
  EEA19112.1 488 --------------NT 489
                 ..............22 PP

>> SAP  SAP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.1     0.032   1.9e+02       9      21 ..     268     280 ..     268     280 .. 0.92
   2 ?   -1.9   0.0      0.51     3e+03       2      22 ..     322     342 ..     321     343 .. 0.82
   3 !   15.5   0.0   1.7e-06      0.01       2      22 ..     371     391 ..     370     392 .. 0.92

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.032
                 HHHHHHHTT--TT CS
         SAP   9 LKeeLkkrGLpts 21 
                 LK+ Lk+ GLp s
  EEA19112.1 268 LKDTLKETGLPLS 280
                 9*********975 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.51
                 TT--HHHHHHHHHHTT--TTS CS
         SAP   2 skltVaeLKeeLkkrGLptsG 22 
                  +l+ ++L   +k ++L + G
  EEA19112.1 322 DNLSRPQLVGMCKYMNLNSFG 342
                 68999***999*988888766 PP

  == domain 3  score: 15.5 bits;  conditional E-value: 1.7e-06
                 TT--HHHHHHHHHHTT--TTS CS
         SAP   2 skltVaeLKeeLkkrGLptsG 22 
                  +l+V+eL+ ++++rGL+t G
  EEA19112.1 371 DSLSVPELQIACASRGLRTHG 391
                 589****************88 PP

>> BPL_N  Biotin-protein ligase, N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.1   0.00026       1.6     223     278 ..     237     290 ..     139     330 .. 0.72
   2 ?    1.6   7.6     0.019   1.1e+02     233     340 ..     429     541 ..     414     559 .. 0.55

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00026
       BPL_N 223 lanlkkqe.aeekeykkvveeleadekaRleflkalLtklgLevneeeeetevpsls 278
                 +++l +++ + +k+ +k  e+l+ + k+  +flk++L++ gL +++e++  ++ +++
  EEA19112.1 237 PNML-PSTyEGQKSRDKKAETLRGTRKEVSAFLKDTLKETGLPLSAETA--KKEEFT 290
                 3344.3443788888999**************************96663..333333 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.019
       BPL_N 233 ekeykkvveeleadekaRleflkalLtklgLevneee.eetevpslsplllsslskee.veelleslkeklaaek.eeeeevikdendtfrlekedeee 328
                 ++++ +++++++a  +   +  ++l+++++Lev+++e +     + ++l +++ ++e   ee +++++++ +     +++e i+d++d+ ++e++d ++
  EEA19112.1 429 QSKDPELSSQIDALRSVLSSIPEELFHEIELEVHNAEgA---ATNRQRLEVIKEQQELiEEENTQNTEQEGKGVAaPKDTENIDDKEDHPKIEASDATT 524
                 45555566666666666666778899999****966633...3333344444444444344455555554444432345699***********999443 PP

       BPL_N 329 aeeaaeeeeee.....k 340
                 +++a+++e+e+     +
  EEA19112.1 525 QQAAEANEAEAdqanaE 541
                 33333322222112211 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (560 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1633  (0.0910815); expected 358.6 (0.02)
Passed bias filter:                      467  (0.0260472); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.71u 0.31s 00:00:01.02 Elapsed: 00:00:00.48
# Mc/sec: 3498.83
//
Query:       EEA19113.1  [L=320]
Description: NUDIX domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.4e-09   35.9   0.1    2.9e-08   33.8   0.0    2.0  2  NUDIX     NUDIX domain


Domain annotation for each model (and alignments):
>> NUDIX  NUDIX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.8   0.0   1.6e-12   2.9e-08       2      66 ..      32     102 ..      31     187 .. 0.66
   2 ?   -0.4   0.1     0.061   1.1e+03      76     113 ..     197     242 ..     169     254 .. 0.62

  Alignments for each domain:
  == domain 1  score: 33.8 bits;  conditional E-value: 1.6e-12
                 EEEEEEEEEEETTSE....EEEEEES.SSSTTTEE.SSEEECBTTS.HHHHHHHHHHHHHHSEEEEEEEEEE CS
       NUDIX   2 lrravgvvllnekge....vLlvrrs.kkpfpgWe.lPgGkvepgE.tpeeAArREleEEtGleaellellg 66 
                 +r+av ++l+ + +     vL +r +  + f+g + +PgGk + +  t+ ++ArRE+ EE+Gl ++  e l 
  EEA19113.1  32 RRAAVLILLYADLNGdlktVLTIRAKtLSSFAGHAaFPGGKADTNHeTAFQTARREASEEIGL-PNIGEPLF 102
                 678899999988866688788888779889999545*******8666999************9.33333333 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.061
                 EEEEE...EEEEEEEEE....EEECSGCSST...STTTEEEEEEEEHH CS
       NUDIX  76 gpygd...eheilyvfl....eevegelepn...denevsevrwvple 113
                 g++++    ++ ++ f     e  ++  +p+   +++ +++v   +le
  EEA19113.1 197 GSWTTwheSDWRMHHFYipisE--KSVTKPRprrKSKRLQDVAITKLE 242
                 3333366678888777767432..333333333566666666555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (320 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       377  (0.0210274); expected 358.6 (0.02)
Passed bias filter:                      318  (0.0177366); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 2124.83
//
Query:       EEA19114.1  [L=448]
Description: hypothetical protein PMAA_013770 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0012   18.3   0.7      0.002   17.5   0.0    1.8  2  DUF5524   Family of unknown function (DUF5524)


Domain annotation for each model (and alignments):
>> DUF5524  Family of unknown function (DUF5524)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.1      0.34     6e+03     167     184 ..     231     248 ..     220     274 .. 0.47
   2 !   17.5   0.0   1.1e-07     0.002      82     129 ..     339     387 ..     309     434 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 0.34
     DUF5524 167 kkkvrlpainskyaskvg 184
                 +   rl +  s y+s  +
  EEA19114.1 231 REMTRLSSNGSSYSSSKD 248
                 333333333333333322 PP

  == domain 2  score: 17.5 bits;  conditional E-value: 1.1e-07
     DUF5524  82 llkhlaagtrkgspvayslpdwyihh.skpptaeqrevpavslpdymvy 129
                 l +h ++ +   s++  slp   + h s pptae+ +v ++s+pdy  +
  EEA19114.1 339 LGQHTSNDSVDISSANESLPVVRVFHvSSPPTAERGDVSVISIPDYARH 387
                 56788888889999999***988755499*****************755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (448 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       639  (0.0356406); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.23s 00:00:00.77 Elapsed: 00:00:00.41
# Mc/sec: 3255.45
//
Query:       EEA19115.1  [L=112]
Description: hypothetical protein PMAA_013780 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (112 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       250  (0.0139439); expected 358.6 (0.02)
Passed bias filter:                      233  (0.0129957); expected 358.6 (0.02)
Passed Vit filter:                        10  (0.000557756); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.36u 0.26s 00:00:00.62 Elapsed: 00:00:00.40
# Mc/sec: 831.07
//
Query:       EEA19116.1  [L=133]
Description: hypothetical protein PMAA_013790 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.044   13.9   0.1       0.49   10.6   0.0    2.1  2  LPD7      Large polyvalent protein-associated domain 7


Domain annotation for each model (and alignments):
>> LPD7  Large polyvalent protein-associated domain 7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.1     0.028   5.1e+02      41      54 ..      15      29 ..      11      32 .. 0.81
   2 ?   10.6   0.0   2.7e-05      0.49      52      78 ..      80     106 ..      70     113 .. 0.77

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.028
        LPD7 41 aaalelAqakw.gsl 54
                 ++++lA+a w ++l
  EEA19116.1 15 TDMMRLAKALWeEAL 29
                58*****99994465 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 2.7e-05
        LPD7  52 gsltvsGseeFkreaweaaaerglevt 78 
                 g ++++Gse+++ ++w+a+  +  +v 
  EEA19116.1  80 GYIRIHGSEAWRVAMWKACGLEPPPVV 106
                 679***************987666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (133 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       421  (0.0234815); expected 358.6 (0.02)
Passed bias filter:                      357  (0.0199119); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.24s 00:00:00.62 Elapsed: 00:00:00.40
# Mc/sec: 1008.40
//
Query:       EEA19117.1  [L=1091]
Description: alpha-mannosidase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.5e-88  296.2   0.6    5.3e-88  295.1   0.6    1.5  1  Glyco_hydro_38N  Glycosyl hydrolases family 38 N-terminal dom
      2e-57  194.7   0.1    2.7e-56  191.0   0.1    2.3  2  Glyco_hydro_38C  Glycosyl hydrolases family 38 C-terminal dom
    1.3e-27   95.8   0.0      3e-27   94.6   0.0    1.7  1  Alpha-mann_mid   Alpha mannosidase middle domain
    1.1e-12   47.9   0.0    4.2e-12   46.0   0.0    2.1  1  Glyco_hydro38C2  Glycosyl hydrolases family 38 C-terminal bet
  ------ inclusion threshold ------
      0.045   12.9   0.0       0.17   11.0   0.0    1.6  1  Glyco_hydro_57   Glycosyl hydrolase family 57


Domain annotation for each model (and alignments):
>> Glyco_hydro_38N  Glycosyl hydrolases family 38 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  295.1   0.6   1.5e-91   5.3e-88       2     285 ..     284     546 ..     283     550 .. 0.96

  Alignments for each domain:
  == domain 1  score: 295.1 bits;  conditional E-value: 1.5e-91
                      EEEEEEEE--SSSSS-HHHHHCCTCHHHHHHHHHHHHHSTT--EEES-CHHHHHHHCCS-CCCHHHHHHHHHCTSEEECTT-SS-B-SSSS-HH CS
  Glyco_hydro_38N   2 vhvvpHsHiDvgWlktvdeyqrrkvqrilssvlellerdpdrkFilseaslferwweeapeekkelvkklvaegrlevvgGgwvenDealpsge 95 
                      v++++H+HiD++Wl++++e+ +rkv+r++s++++l++r+p+ +F+ s+a++++++++++p  ++++ k++v++gr++++gG+wve+D++lpsge
       EEA19117.1 284 VYAIGHCHIDTCWLWPFAET-KRKVARSWSNQCDLMDRYPEHRFTVSQAQQYKWLKTYYPSVFDRV-KSYVKKGRFQPIGGSWVEHDTNLPSGE 375
                      899*****************.*********************************************.*************************** PP

                      HHHHHHHCCCHHHHCCH--EESEEEESSSSSB-TCHHHHHHCTT--EEEESSS-HHCHCCHHHTT-SCEEEE-TTSTEEEEEE--TT.SSHCCC CS
  Glyco_hydro_38N  96 slirqlleGqrflkeefgvrpkvaWliDpFGysatlPqllkkaGidsfltqrlsyndknkfaeqkhlefiWrgsdgteilthmlpadsydptyg 189
                      sl+rq+l+Gqr ++++fg r++++Wl+D+FGys++lPql++ aG+++f+tq+ls+n++n+f   +h++f+W + dg+++l+hm pa+    ty+
       EEA19117.1 376 SLVRQFLYGQRLFESNFGERCRTFWLPDTFGYSSQLPQLCQLAGMERFFTQKLSWNNINSF---PHTTFNWVALDGSQVLCHMTPAE----TYT 462
                      *************************************************************...*********************98....899 PP

                      CCC.GGGTTTHHHCHHHHHHCHHHHHTTSSSSEEEEEECEETHCCCCHHHHCCHHHHHHHHHHC....SSEEEEC--H.HHHHHHHHHHS...H CS
  Glyco_hydro_38N 190 fqfdfkrdenvkeraekllaqvkklaektrtnevllplGddfadgqggnteklleeinrsneke....slpkvqfgtp.seYfdalekenaefp 278
                      +++          ++ ++ +++++++++++++++ll++G++  dg+gg+t ++le+++r++  +    +lp+v++ t  +e+fd+l++     +
       EEA19117.1 463 ASA----------HFGDVKRSISQHKSLDQDKTSLLVFGKG--DGGGGPTFEHLEKLRRCRGLSdkigLLPRVKMNTSvDEFFDQLQE-----K 539
                      999..........9***************************..*****************995557879*******988*********.....3 PP

                      CE-ESSB CS
  Glyco_hydro_38N 279 tkdsddf 285
                      + ++ +f
       EEA19117.1 540 AAKGVNF 546
                      3334444 PP

>> Glyco_hydro_38C  Glycosyl hydrolases family 38 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0      0.11     4e+02     130     158 ..     457     485 ..     450     488 .. 0.89
   2 !  191.0   0.1   7.5e-60   2.7e-56       1     214 []     725     933 ..     725     933 .. 0.97

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.11
                      TTCEEEEETTTCEEEEESSTTTT...S.. CS
  Glyco_hydro_38C 130 qaefatdengfgvikRptdqntsweaakf 158
                       ae++t++  fg +kR   q +s +++k+
       EEA19117.1 457 PAETYTASAHFGDVKRSISQHKSLDQDKT 485
                      689*****************999998875 PP

  == domain 2  score: 191.0 bits;  conditional E-value: 7.5e-60
                      XTTSS-EEEE.TTTSSEEEEESTTTS-EEE....EEEEEEEEEEECS-S-SSS--BSTT-EEEE--.S-EEECEE-SS-EEEEEEETTES...E CS
  Glyco_hydro_38C   1 leNgflkveidaknGtlksiydkeakrevlke.qvgnqfaayedapdssdaydfkpdneekplevsekeveviesgplvaevtvkfkieaesti 93 
                      l N+ lkv i  ++G + s+yd ea+rev+   +   q+++++d+p +++a+d++ ++ + ++e+++++  + e++p   +v+++++i++ s+i
       EEA19117.1 725 LTNEKLKVDI--QDGVIVSLYDVEAEREVISRgGKAGQLVLFDDKPLYWQAWDVEVFHLDSRKELKSSKTSIAENSPHCVSVVTETQISDHSWI 816
                      6799999999..88****************9987788********************************************************* PP

                      EEEEEEE....ECCCCEEEEEEEE-TTECEEEEEEEE---TTCEEEEETTTCEEEEESSTTTT...S..SEGGGG-EEESSEEEEE-SSEEEEE CS
  Glyco_hydro_38C  94 sqeirLy....kgkkriefevkvdweekevllkvafpidiqaefatdengfgvikRptdqntsweaakfeviagnyypiqsfvdlqdesygvav 183
                      +++i+L+     + +++ef+ +++w+e++++lkv+fp+d+++++a++e+++g+++Rpt++ntsw++akfev      + ++++dl++  ygv++
       EEA19117.1 817 KTTISLKaavnSEPSYVEFDSEIEWRENKKFLKVEFPVDVHNTEASYETQYGIVRRPTHYNTSWDMAKFEV------CSHKWADLSEYGYGVSI 904
                      *******99999999********************************************************......***************** PP

                      EECS-EEEEE-SSTTEEEEEEEEEBSSS-TT CS
  Glyco_hydro_38C 184 lndskyGvssleqggqleLsLlRrplypdpr 214
                      lnd+kyG+++   g+ ++LsL R+p++pd++
       EEA19117.1 905 LNDCKYGFAT--VGNVMRLSLMRAPKAPDAH 933
                      **********..79***************85 PP

>> Alpha-mann_mid  Alpha mannosidase middle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.6   0.0   8.4e-31     3e-27       1      96 []     556     655 ..     556     655 .. 0.94

  Alignments for each domain:
  == domain 1  score: 94.6 bits;  conditional E-value: 8.4e-31
                     EE--GGGTSSCHHHHHHHHHHHHHHHHHHHCC.TTT....-SCGC-HHHHHHHHHHHHHHHTCTTTTTT-S-HHHHHHCCHHHHHHHHHHHHHCC CS
  Alpha-mann_mid   1 elhrgtfTSrarlKrlnrkleslLraaellss.aaa....skgyeypkeeleelwkalllnqfHDilpGtsieeVyedaeerlaealkeleklle 90 
                     elhrgt+TS++++Kr nrk+e lLr++e++++ a +    + +y+ypke+l+++w+++ll+qfHD+lpG+si ++yed++e +ae+++++ +l +
      EEA19117.1 556 ELHRGTYTSQSNNKRNNRKAEFLLREIEYFATlA-TvgkmKSSYKYPKEDLDNMWESVLLCQFHDCLPGSSIGMCYEDTKEIYAEVFATGHRLKK 649
                     79******************************62.3455599***************************************************** PP

                     CCCCCC CS
  Alpha-mann_mid  91 salrkL 96 
                     +al++L
      EEA19117.1 650 EALAAL 655
                     999886 PP

>> Glyco_hydro38C2  Glycosyl hydrolases family 38 C-terminal beta sandwich domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.0   0.0   1.2e-15   4.2e-12      12      69 .]    1011    1088 ..     992    1088 .. 0.78

  Alignments for each domain:
  == domain 1  score: 46.0 bits;  conditional E-value: 1.2e-15
                       T.....T--EEEEEEESSSSSBEEE-EETT.SCEEEEE-TTSSB-...................-TTSEEXTTXEEEEE CS
  Glyco_hydro38C2   12 d.....eddlllRlynlseegedatlslsqpvksvnvknllEttlape................eleielkPmEIrTfi 69  
                       +     ++++++Rly++ +++++ t+++  pvk+v+++n+lE+++ +e                +++iel+P+E++Tf+
       EEA19117.1 1011 ElakrpGQSIIMRLYESLGGKARGTIHTTLPVKRVWKTNVLEDDE-AEfpilqnhkdatiegqkSVDIELRPFEVATFR 1088
                       044455***************************************.234555555568889999**************7 PP

>> Glyco_hydro_57  Glycosyl hydrolase family 57
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   4.9e-05      0.17     148     207 ..     372     432 ..     332     559 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 4.9e-05
                     S-HHHHHHHHHHHHHHHHHHHSS--SBEE-GG.G-B--SHHHHHHHTT--EEEE-C----- CS
  Glyco_hydro_57 148 pdsedieaqvkkarelyeeyfgqePrgfwlpE.lavspeileilaelGfeylftdelaeil 207
                     p  e + +q   ++ l+e+ fg++ r+fwlp  + +s +++++ + +G+e +ft +l++  
      EEA19117.1 372 PSGESLVRQFLYGQRLFESNFGERCRTFWLPDtFGYSSQLPQLCQLAGMERFFTQKLSWNN 432
                     44578889999999*****************8356*****************999855544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1091 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       367  (0.0204696); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.88u 0.32s 00:00:01.20 Elapsed: 00:00:00.57
# Mc/sec: 5781.26
//
Query:       EEA19118.1  [L=291]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      3e-27   94.3   0.5    9.9e-27   92.6   0.5    1.9  1  NuA4            Histone acetyltransferase subunit NuA4


Domain annotation for each model (and alignments):
>> NuA4  Histone acetyltransferase subunit NuA4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.6   0.5   5.5e-31   9.9e-27       1      79 []     101     198 ..     101     198 .. 0.95

  Alignments for each domain:
  == domain 1  score: 92.6 bits;  conditional E-value: 5.5e-31
        NuA4   1 eLkellkkkrelekelakleeqIydkEteYleetssvGNiikGFdnylk....................ssssssaaerrkrkvtdedriFSlSSvtsv 79 
                 eL+++l+kkr ++k++a+leeqIy++E++Yle+t s+GNiikGFdny+k                    s+++  ++ rrk+ +++ dr+FS+SS++++
  EEA19118.1 101 ELRDTLQKKRLMDKSMAQLEEQIYRFEQSYLEDT-SAGNIIKGFDNYIKgsssssglggggggslsitgSTGTAITGGRRKTGFSEVDRVFSKSSASFM 198
                 69********************************.***************************999998777777788889****************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (291 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1710  (0.0953762); expected 358.6 (0.02)
Passed bias filter:                      616  (0.0343577); expected 358.6 (0.02)
Passed Vit filter:                        95  (0.00529868); expected 17.9 (0.001)
Passed Fwd filter:                        32  (0.00178482); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.92u 0.40s 00:00:01.32 Elapsed: 00:00:00.56
# Mc/sec: 1577.04
//
Query:       EEA19119.1  [L=193]
Description: Ctr copper transporter family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.4e-30  104.7   2.2      8e-30  104.4   2.2    1.1  1  Ctr       Ctr copper transporter family
  ------ inclusion threshold ------
      0.061   13.3   0.2      0.085   12.8   0.2    1.2  1  T2SSF     Type II secretion system (T2SS), protein F


Domain annotation for each model (and alignments):
>> Ctr  Ctr copper transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.4   2.2   8.9e-34     8e-30       1     148 []      24     180 ..      24     180 .. 0.76

  Alignments for each domain:
  == domain 1  score: 104.4 bits;  conditional E-value: 8.9e-34
         Ctr   1 mlFhwstddt.ilfrsWritskgqlagsciglfllaifyeflralrerlerewdrhlarsrekrkaassplvdssssseeeaea............... 83 
                 mlF+wst+++ i+f +Wr++ +g+l++s+++++ll+++ye++r     + r ++  +++++++++ +ss lvd+++   ++ +                
  EEA19119.1  24 MLFTWSTHNMcIIFPEWRVQGTGSLIASLFAIILLCAGYEAVR----SFTRLYE--VSHTQRLKAFSSSVLVDTENVGPRTMSGdvefpeedtrregla 116
                 9******************************************....6655444..2345556677777777766666666555555555555444444 PP

         Ctr  84 .kstsslskseakksvrttpe..............qqlirallyvvqvllaYilMLlvMtyNvglflavilGagvGeflf 148
                   ++                                ++i a+ly+ qv++++++MLl+MtyN++++++v +Ga+vG+++f
  EEA19119.1 117 rFTN----------------SllvgrdskqvlerrGRVIMAALYAAQVFYSFFIMLLFMTYNGWVMISVAVGAFVGYLVF 180
                 3222................22233333344444456*****************************************98 PP

>> T2SSF  Type II secretion system (T2SS), protein F
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.2   9.5e-06     0.085       7     124 ..      56     175 ..      52     176 .. 0.95

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 9.5e-06
                 HHHHTT--HHHHHHHHHHHHSSHHHHHHHHHHHHHHHTTSSHHHHHC.T-TT.TS.-HHHHHHHHHHHHHT-HHHHHHHHHHHHHHHHHHHHHHHHHHH CS
       T2SSF   7 tllsaGvplveaLellaeeaengplaeelkriarrlraGgslseale.rtpssef.pelvvqlirageeggnLaevLerlaeyleeerelrrkllaall 103
                 +ll aG   v+++++l e+++ ++l+   ++++ + ++ g+   + + ++p+++  +e +++++++   g +  +vLer  + +++ +  ++   + ++
  EEA19119.1  56 ILLCAGYEAVRSFTRLYEVSHTQRLKAFSSSVLVDTENVGPRTMSGDvEFPEEDTrREGLARFTNSLLVGRDSKQVLERRGRVIMAALYAAQVFYSFFI 154
                 7999************************************8888888999999999******************************************* PP

                 TTXXXXXXXXXXXXXXXXXXX CS
       T2SSF 104 epllllvvallvllillaill 124
                   l++ + +++++++ ++ ++
  EEA19119.1 155 MLLFMTYNGWVMISVAVGAFV 175
                 *************99998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (193 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       758  (0.0422779); expected 358.6 (0.02)
Passed bias filter:                      406  (0.0226449); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.34s 00:00:00.94 Elapsed: 00:00:00.55
# Mc/sec: 1050.45
//
Query:       EEA19120.1  [L=158]
Description: Ctr copper transporter family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.8e-25   89.2  14.1    1.5e-24   87.3  14.1    1.7  1  Ctr       Ctr copper transporter family


Domain annotation for each model (and alignments):
>> Ctr  Ctr copper transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.3  14.1   8.6e-29   1.5e-24       1     148 []      24     145 ..      24     145 .. 0.84

  Alignments for each domain:
  == domain 1  score: 87.3 bits;  conditional E-value: 8.6e-29
         Ctr   1 mlFhwstddt.ilfrsWritskgqlagsciglfllaifyeflralrerlerewdrhlarsrekrkaassplvdssssseeeaeakstsslskseakksv 98 
                 mlF+wst+++ i+f +Wr++ +g+l++s+++++ll+++ye++r     + r ++  +++++++++ +ss lv                    + +k+  
  EEA19120.1  24 MLFTWSTHNMcIIFPEWRVQGTGSLIASLFAIILLCAGYEAVR----SFTRLYE--VSHTQRLKAFSSSVLVG-------------------RDSKQVL 97 
                 9******************************************....7766444..22344445555555554...................3345666 PP

         Ctr  99 rttpeqqlirallyvvqvllaYilMLlvMtyNvglflavilGagvGeflf 148
                 + + +  +i a+ly+ qv++++++MLl+MtyN++++++v +Ga+vG+++f
  EEA19120.1  98 ERRGR--VIMAALYAAQVFYSFFIMLLFMTYNGWVMISVAVGAFVGYLVF 145
                 66666..99***************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (158 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       900  (0.050198); expected 358.6 (0.02)
Passed bias filter:                      419  (0.02337); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.33s 00:00:00.92 Elapsed: 00:00:00.54
# Mc/sec: 881.54
//
Query:       EEA19121.1  [L=155]
Description: Ctr copper transporter family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.8e-14   52.5   0.1    9.8e-14   52.2   0.1    1.1  1  Ctr       Ctr copper transporter family


Domain annotation for each model (and alignments):
>> Ctr  Ctr copper transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.2   0.1   5.5e-18   9.8e-14       1     123 [.      24     155 .]      24     155 .] 0.72

  Alignments for each domain:
  == domain 1  score: 52.2 bits;  conditional E-value: 5.5e-18
         Ctr   1 mlFhwstddt.ilfrsWritskgqlagsciglfllaifyeflralrerlerewdrhlarsrekrkaassplvdssssseeeaea............... 83 
                 mlF+wst+++ i+f +Wr++ +g+l++s+++++ll+++ye++r     + r ++  +++++++++ +ss lvd+++   ++ +                
  EEA19121.1  24 MLFTWSTHNMcIIFPEWRVQGTGSLIASLFAIILLCAGYEAVR----SFTRLYE--VSHTQRLKAFSSSVLVDTENVGPRTMSGdvefpeedtrregla 116
                 9******************************************....6655444..2345556677777777766666666555555555555444444 PP

         Ctr  84 .kstsslskseakksvrttpe..............qqlirallyvvqvllaYilM 123
                   ++                                ++i a+ly+ qv++++++M
  EEA19121.1 117 rFTN----------------SllvgrdskqvlerrGRVIMAALYAAQVFYSFFIM 155
                 3222................22233333344444456*****************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (155 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       411  (0.0229238); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.36s 00:00:00.90 Elapsed: 00:00:00.55
# Mc/sec: 848.91
//
Query:       EEA19122.1  [L=496]
Description: F-box and JmjC domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.1e-16   59.1   0.1    2.1e-11   44.0   0.0    2.2  2  Cupin_8     Cupin-like domain
    1.2e-09   38.6   0.2     0.0019   18.6   0.1    2.5  2  JmjC        JmjC domain, hydroxylase
    8.8e-07   28.7   0.5      2e-06   27.6   0.5    1.6  1  F-box-like  F-box-like
    1.1e-06   28.4   0.1    2.4e-06   27.2   0.1    1.6  1  F-box       F-box domain
  ------ inclusion threshold ------
      0.055   12.9   0.0       0.09   12.2   0.0    1.3  1  Cupin_4     Cupin superfamily protein


Domain annotation for each model (and alignments):
>> Cupin_8  Cupin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.0   0.0   1.7e-05     0.062      12      45 ..     179     212 ..     172     235 .. 0.80
   2 !   44.0   0.0   5.9e-15   2.1e-11     130     250 ..     281     400 ..     219     403 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 1.7e-05
     Cupin_8  12 skPviikgalkdwpalqkwtddeylleylkekae 45 
                  +P+i+++ +k+wp +qkw++de l +y +   +
  EEA19122.1 179 DRPFILTEPVKEWPVFQKWSTDELLAKYSSTIFR 212
                 69******************86666666555454 PP

  == domain 2  score: 44.0 bits;  conditional E-value: 5.9e-15
     Cupin_8 130 peavnlWlGnsasvsslHkDh..yeNlycvvrGrKkftLfpPsda....pflyeaslsptedgtvvssvdveepdlekfprlkdakkalevtlnaGevL 222
                 p++  l +G+++s s +HkD+     + +v+rG K +++fp s      p +y++++    +++v+s+++++e  l    +++++  +le    +GevL
  EEA19122.1 281 PDSRWLIIGPERSGSTFHKDPnaTSAWNAVLRGSKYWIMFPSSSKlpppPGVYVSED----QSEVTSPLSIAEWLLGFHAEARRTPGCLEGICAEGEVL 375
                 5555689**************9999***************99876222246688774....5689***********9999*****99************ PP

     Cupin_8 223 ylPalWfHeVkslaeeplhlavnywydm 250
                 ++P++W+H V +l  ep ++a+  ++ +
  EEA19122.1 376 HVPSGWWHLVVNL--EP-SIAITQNFVP 400
                 *************..88.8998887765 PP

>> JmjC  JmjC domain, hydroxylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   1.1e-06    0.0039       1      42 [.     285     325 ..     285     338 .. 0.95
   2 !   18.6   0.1   5.4e-07    0.0019      87     114 .]     371     398 ..     363     398 .. 0.95

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 1.1e-06
                 EEEEE-TT-EEEEE--GGG-EEEEEEEEES-EEEEEE-GGGH CS
        JmjC   1 wlylgmpksttpwhiedqglySinylhfgapkvWyiipeekk 42 
                 wl +g+++s   +h + ++++ +++  ++++k+W ++p++ k
  EEA19122.1 285 WLIIGPERSGSTFHKDPNATS-AWNAVLRGSKYWIMFPSSSK 325
                 899*****************9.9***************9865 PP

  == domain 2  score: 18.6 bits;  conditional E-value: 5.4e-07
                 TT-EEEE-TT-EEEEEESSSEEEEEEEE CS
        JmjC  87 pgefVfvfpgayHsvfnlgfniaeavnf 114
                 +ge++ v++g++H v+nl  +ia+++nf
  EEA19122.1 371 EGEVLHVPSGWWHLVVNLEPSIAITQNF 398
                 79*************************9 PP

>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.6   0.5   5.6e-10     2e-06       4      44 ..      58      97 ..      55     100 .. 0.94

  Alignments for each domain:
  == domain 1  score: 27.6 bits;  conditional E-value: 5.6e-10
  F-box-like  4 LPdEiLlqIFsyLppsdLlrlalVCrrWrrvaldtplLWrr 44
                +PdE++l+ ++yL+  +Llrl ++C+  + +++++  LW+ 
  EEA19122.1 58 IPDELILTCLEYLDSASLLRLGCTCKALYAFTRSE-DLWKA 97
                8*******************************999.***85 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.2   0.1   6.8e-10   2.4e-06       2      46 ..      54      98 ..      53     100 .. 0.93

  Alignments for each domain:
  == domain 1  score: 27.2 bits;  conditional E-value: 6.8e-10
                HHHHS-HHHHHHHHHTS-HHHHHHHCTT-HHHHHHHTTHHHHHHH CS
       F-box  2 tlsrLPsevlrhILerLplsdllalrrVSkgwrilidsdrlwcks 46
                t+   P+e+++ +Le+L+  +ll+l +++k ++ +++s  lw+ +
  EEA19122.1 54 TFNIIPDELILTCLEYLDSASLLRLGCTCKALYAFTRSEDLWKAF 98
                57779*************************************866 PP

>> Cupin_4  Cupin superfamily protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   2.5e-05      0.09     177     268 ..     366     454 ..     357     483 .. 0.64

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2.5e-05
                 EEEE-TT-EEEE-TT-EEEEEBBT-CCEEEEEECCEEHCCHHHCHHHHHHHHHHHH...HHHCTSCHHCTCGTTTGGGTTS-HHHHHHHHHHHHH CS
     Cupin_4 177 dfvLepGDlLYlPrgviHqgvaedesltlSvglraptaaellesvldllldklpei...derlrdallravqargeidsdsidalaaqlsellrd 268
                 + + + G +L +P+g++H  v +++s+ ++  + +      +   ld+l++k+ ++   ++++ d+ +r v++++       d l + l+el ++
  EEA19122.1 366 EGICAEGEVLHVPSGWWHLVVNLEPSIAITQNFVPRGHLSAA---LDFLQNKADQVsgfRKNVDDPYSRFVEKMKLSYP---DLLDEALEELAKQ 454
                 566679************************998776665544...4444444444433355555555555444443322...3333333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (496 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       420  (0.0234257); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.71u 0.34s 00:00:01.05 Elapsed: 00:00:00.54
# Mc/sec: 2749.95
//
Query:       EEA19123.1  [L=397]
Description: eukaryotic translation initiation factor 4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.2e-44  152.2   1.1    2.1e-44  151.4   1.1    1.4  1  DEAD             DEAD/DEAH box helicase
    3.6e-32  111.0   0.2      5e-31  107.3   0.1    2.5  3  Helicase_C       Helicase conserved C-terminal domain
    8.3e-07   29.2   0.0    1.3e-06   28.5   0.0    1.3  1  ResIII           Type III restriction enzyme, res subunit
    0.00012   21.9   0.2    0.00022   21.0   0.2    1.4  1  AAA_30           AAA domain
    0.00047   20.5   0.2     0.0032   17.8   0.1    2.1  2  AAA_19           AAA domain
     0.0081   16.4   1.2      0.054   13.8   1.2    2.3  1  AAA_22           AAA domain
     0.0098   15.3   0.0      0.021   14.2   0.0    1.5  1  CMS1             U3-containing 90S pre-ribosomal complex subu
  ------ inclusion threshold ------
      0.075   12.8   0.1       0.29   10.9   0.0    2.0  2  fragilysinNterm  N-terminal domain of fragilysin
      0.081   12.9   0.0       0.81    9.7   0.0    2.3  1  Flavi_DEAD       Flavivirus DEAD domain


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  151.4   1.1     1e-47   2.1e-44       2     175 ..      49     213 ..      48     214 .. 0.96

  Alignments for each domain:
  == domain 1  score: 151.4 bits;  conditional E-value: 1e-47
                 HHHHHHHHHHHTTCEEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTCSE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   2 diQaeaiplilgggdvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngvdi 100
                 +iQ++ai  +++g+dv+++a+ G+GKT+ f+i +lq++    + ++ +ali++PtreLa+q+ + +  ++++++++++++igg++ r+++++l+ g+++
  EEA19123.1  49 AIQQRAIMPVIKGNDVIAQAQSGTGKTATFSISALQKID--GSLKACQALILAPTRELAQQIQKVVVAIGDFMSIECHACIGGTNVREDMKALQDGPQV 145
                 79************************************4..589999**********************************************999*** PP

                 EEEEHHHHHHHHHCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD 101 vvgtpgrlddllstgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlpkdvkk 175
                 vvgtpgr++d+++++ l++++++++VlDEad++l+ gf ++i  i++ l       +++ qv++lSAT+p+dv +
  EEA19123.1 146 VVGTPGRVQDMIQRRVLRTDNIKMFVLDEADEMLSRGFTEQIYDIFQLL-------PQSTQVVLLSATMPQDVLE 213
                 *************************************************.......45567*********99865 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       2.8   5.6e+03      17      51 ..      93     131 ..      82     150 .. 0.53
   2 ?    0.5   0.0      0.38   7.6e+02      32      74 ..     191     230 ..     161     237 .. 0.72
   3 !  107.3   0.1   2.5e-34     5e-31       2     111 .]     250     358 ..     249     358 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 2.8
                 SEEEEEESSHHHHHH...HHHHHHHT.TSTEEEESTTST CS
  Helicase_C  17 gkilifvntidrlek...vklllekk.gikvavlhgelp 51 
                  ++li ++t++ +++   v +    + +i++ ++ g ++
  EEA19123.1  93 CQALILAPTRELAQQiqkVVVAIGDFmSIECHACIGGTN 131
                 567888888885443321111112223444444444444 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.38
                 HHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESG CS
  Helicase_C  32 vklllekkgikvavlhgelpqnereeileqfnkgesdvLiatd 74 
                 ++ll   ++ +v+ l +++pq + +e+ ++f ++ +++L+  d
  EEA19123.1 191 FQLL--PQSTQVVLLSATMPQ-DVLEVTTKFMRDPVRILVKKD 230
                 3555..556788777776666.568899999888999998766 PP

  == domain 3  score: 107.3 bits;  conditional E-value: 2.5e-34
                 HHHHHHHHHHHTTTTSEEEEEESSHHHHHH.HHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSSHHH CS
  Helicase_C   2 kleallellkleeeggkilifvntidrlek.vklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprnvts 99 
                 kl++l +l+ +++   +++if+nt+++++  ++ l + ++++v ++hg+++q++r+ i+++f++g+s+vLiatd ++rGid+++v+lVin+dlp n ++
  EEA19123.1 250 KLDTLSDLY-ETVTITQAVIFCNTRRKVDWlTDKL-TARDFTVSAMHGDMEQSQRDVIMKEFRSGSSRVLIATDLLARGIDVQQVSLVINYDLPANREN 346
                 667777776.788999************7665555.3458*********************************************************** PP

                 HHHHHTTSSSTT CS
  Helicase_C 100 yiqriGRtgRag 111
                 yi+riGR gR+g
  EEA19123.1 347 YIHRIGRGGRFG 358
                 **********86 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.5   0.0   6.7e-10   1.3e-06      25     170 ..      62     208 ..      45     209 .. 0.79

  Alignments for each domain:
  == domain 1  score: 28.5 bits;  conditional E-value: 6.7e-10
                 SEEEEEESTTSTHHHHH.HHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG.........GEEEESSS-B--.......-SEEEEEHHHHHHT CS
      ResIII  25 krglikmaTGtGKTlva.aklierllkkgkeekflflvprkslleqtleefkkflseayke.....igkkvsgdkkkakekdstnkkilvttiqsldad 117
                 + ++ ++  GtGKT +  +++ +++  + k  ++l+l+p+++l +q ++ +  + +    e      g++v++d k      ++  +++v t  +++  
  EEA19123.1  62 NDVIAQAQSGTGKTATFsISALQKIDGSLKACQALILAPTRELAQQIQKVVVAIGDFMSIEchaciGGTNVREDMKAL----QDGPQVVVGTPGRVQDM 156
                 567889999*******99******************************655444444333333354566666666666....9999************* PP

                 H........HHHTTT-SEEEEETGGGTTS.TTTHHHHHT-....--SEEEEEESS-S CS
      ResIII 118 seeeeeeseellrdrfdviiiDEaHrlgakkswreilekf....keavllglTATpe 170
                 +     ++  l+ d++++++ DEa  + +  + ++i + f    ++  ++ l+AT++
  EEA19123.1 157 I-----QRRVLRTDNIKMFVLDEADEMLSRGFTEQIYDIFqllpQSTQVVLLSATMP 208
                 *.....8999999**************998777888777744454577788899975 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0   0.2   1.1e-07   0.00022       5     119 ..      50     200 ..      47     205 .. 0.66

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 1.1e-07
      AAA_30   5 eQaaavealltsgdrvavltGpAGtGKt..talkalreaweaa.ggrviglAptgkaAkvLae.............elgieastiakllkrlk...... 81 
                  Q++a+  +++++d  +++++  GtGKt  ++++al+++  +    + ++lApt + A+++++             ++ i + ++ + +k+l+      
  EEA19123.1  50 IQQRAIMPVIKGND--VIAQAQSGTGKTatFSISALQKIDGSLkACQALILAPTRELAQQIQKvvvaigdfmsiecHACIGGTNVREDMKALQdgpqvv 146
                 59999999999999..9**********8225688999999999779****************7555444333332211123333333333333677889 PP

      AAA_30  82 .............grarlepgtllivDEagmv....dtkqlaallkaaekagakv 119
                              +  r ++ ++++ DEa  +     t+q+ ++++ + + +++v
  EEA19123.1 147 vgtpgrvqdmiqrRVLRTDNIKMFVLDEADEMlsrgFTEQIYDIFQLLPQ-STQV 200
                 99999888888753344445599999999644344335555555555555.4444 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.1   1.6e-06    0.0032       1      82 [.      51     131 ..      51     212 .. 0.61
   2 ?    0.4   0.0      0.37   7.4e+02      39      75 ..     260     296 ..     247     381 .. 0.77

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 1.6e-06
      AAA_19   1 qreave.alkekvllvtaGpGtGKTrvlkhivallvelggvkpeeillvaftgrAakelrerlaalgaeatTiHrlalldfdd 82 
                 q++a+   +k + ++  a  GtGKT +     al +  g++k+ + l++a+t+  a+++++ + a  ++ + i   a ++ ++
  EEA19123.1  51 QQRAIMpVIKGNDVIAQAQSGTGKTATFSI-SALQKIDGSLKACQALILAPTRELAQQIQKVVVA-IGDFMSIECHACIGGTN 131
                 7888887999999*************9864.444444566899*****************99844.44433333223333333 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.37
      AAA_19  39 gvkpeeillvaftgrAakelrerlaalgaeatTiHrl 75 
                 +v   + ++ + t+r ++ l+++l+a +   + +H+ 
  EEA19123.1 260 TVTITQAVIFCNTRRKVDWLTDKLTARDFTVSAMHGD 296
                 4556788999999999999999997777667777754 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.8   1.2   2.7e-05     0.054      72     131 ..     147     208 ..      64     214 .. 0.57

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2.7e-05
      AAA_22  72 rlsseellealeqalraravielliiDEaqh.lrseealeeLrsllnl..srkgvqliLvGtp 131
                  ++  ++ +++++ + +++ i+++++DEa+  l s    e++ +++ l  ++++v l+ + +p
  EEA19123.1 147 VGTPGRVQDMIQRRVLRTDNIKMFVLDEADEmL-SRGFTEQIYDIFQLlpQSTQVVLLSATMP 208
                 55666777888888888888***********77.99999999999998666666666555555 PP

>> CMS1  U3-containing 90S pre-ribosomal complex subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.0   1.1e-05     0.021     180     209 ..     145     174 ..     131     181 .. 0.91

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 1.1e-05
        CMS1 180 iavGtpgRildLleeeslsvdeLkrivlDa 209
                 + vGtpgR+ d+++  +l+ d++k  vlD 
  EEA19123.1 145 VVVGTPGRVQDMIQRRVLRTDNIKMFVLDE 174
                 789*************************96 PP

>> fragilysinNterm  N-terminal domain of fragilysin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0       2.9   5.7e+03      28      68 ..     279     318 ..     269     333 .. 0.69
   2 ?   10.9   0.0   0.00014      0.29      77     106 ..     356     385 ..     354     394 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 2.9
  fragilysinNterm  28 lkenselrtvsvkaikrvkieednenvrlfeGrdkdsisai 68 
                      l +    r   v+a ++ ++e++ ++v + e r   s  +i
       EEA19123.1 279 LTDKLTARDFTVSAMHG-DMEQSQRDVIMKEFRSGSSRVLI 318
                      55566667777777776.57777787777666665555555 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00014
  fragilysinNterm  77 rlqrnGelidyivykekermaeiaeyyaah 106
                      r+ r G  i++++  + ++m ei ++y+++
       EEA19123.1 356 RFGRKGVAINFVTADDVRMMREIEQFYNTQ 385
                      899************************976 PP

>> Flavi_DEAD  Flavivirus DEAD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.0   0.00041      0.81       6      54 ..      63     113 ..      58     216 .. 0.68

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00041
                 EEEEE--TTS-TTTTHHHHHHHHH..HHTT--EEEEESSHHHHHHHHHHTT CS
  Flavi_DEAD   6 ltvldlhPGaGktrkvlpelvkea..ierrlrtlvLaPtrvvlaemeealk 54 
                   + ++  G+Gkt  +  + +++     +  ++l+LaPtr  ++ +++ + 
  EEA19123.1  63 DVIAQAQSGTGKTATFSISALQKIdgSLKACQALILAPTRELAQQIQKVVV 113
                 556678899****99988888875114577899*******99988877554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       594  (0.0331307); expected 358.6 (0.02)
Passed bias filter:                      488  (0.0272185); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.66u 0.38s 00:00:01.04 Elapsed: 00:00:00.56
# Mc/sec: 2150.63
//
Query:       EEA19124.1  [L=352]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    0.00031   20.8   1.5      0.098   12.7   0.1    2.4  2  DUF1664         Protein of unknown function (DUF1664)
  ------ inclusion threshold ------
      0.022   15.1   1.6      0.083   13.3   0.4    2.4  3  CLZ             C-terminal leucine zipper domain of cyclic nu
      0.025   14.7   0.8      0.054   13.6   0.8    1.5  1  ADIP            Afadin- and alpha -actinin-Binding
      0.026   14.7   0.3       0.19   11.9   0.1    2.3  2  Cnn_1N          Centrosomin N-terminal motif 1
      0.031   14.7   1.9        2.2    8.7   0.1    3.2  2  FlaC_arch       Flagella accessory protein C (FlaC)
      0.066   13.9   1.3        1.3    9.7   0.4    2.5  2  YabA            Initiation control protein YabA
      0.071   12.3   0.1       0.14   11.3   0.1    1.5  1  Taxilin         Myosin-like coiled-coil protein
      0.077   13.3   0.2        1.9    8.8   0.0    2.4  2  Retrotrans_gag  Retrotransposon gag protein
       0.14   13.3   1.5        2.1    9.5   0.2    2.5  2  SOGA            Protein SOGA
       0.19   11.9   1.2        6.2    7.1   0.2    2.8  3  JIP_LZII        JNK-interacting protein  leucine zipper II
       0.19   11.9   2.4       0.39   10.9   2.4    1.6  1  ATG16           Autophagy protein 16 (ATG16)
       0.27   11.4   1.3       0.53   10.5   0.8    1.8  2  Fib_alpha       Fibrinogen alpha/beta chain family


Domain annotation for each model (and alignments):
>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.1   0.3    0.0017       2.6      56     110 ..      26      80 ..      10      82 .. 0.89
   2 !   12.7   0.1   6.5e-05     0.098      54     120 ..      77     143 ..      74     147 .. 0.94

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0017
     DUF1664  56 slaatkrhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeav 110
                 +l++   hL +rid + ++l + ++ s+  +++++++ + +++++ +  ++k+ v
  EEA19124.1  26 QLRREHVHLVDRIDDMSTQLVSYNDKSQTYEQNLSTLDGLVKTLQAENYTLKNEV 80 
                 6788889***********************************9999988887766 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 6.5e-05
     DUF1664  54 seslaatkrhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeavegleskleri 120
                 +++++ ++ +L++ri+ + +++ +     ++  +  ++++ + +++g +++++++ v+gl+++++++
  EEA19124.1  77 KNEVTLVRTKLTARIEGISQQITAFLSGDNAAIDATKQLKLEFRAMGLQMSELSKSVSGLKGEIASV 143
                 67888999*******************************************************9986 PP

>> CLZ  C-terminal leucine zipper domain of cyclic nucleotide-gated channels
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.4   5.6e-05     0.083      22      70 ..      48      96 ..      34      97 .. 0.89
   2 ?   -3.3   0.0       8.1   1.2e+04      36      49 ..     122     135 ..     107     145 .. 0.48
   3 ?   -0.5   0.0       1.1   1.6e+03      26      47 ..     159     180 ..     153     185 .. 0.74

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 5.6e-05
         CLZ 22 agaeqkeleekverLessLeaLqtrlarLlaeyessqrkLkqRitkLEk 70
                 +++ ++ e++++ L++ +++Lq     L +e++ + +kL++Ri+ + +
  EEA19124.1 48 YNDKSQTYEQNLSTLDGLVKTLQAENYTLKNEVTLVRTKLTARIEGISQ 96
                4578899*************************************98765 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 8.1
         CLZ  36 LessLeaLqtrlar 49 
                 +  ++  L + +  
  EEA19124.1 122 MGLQMSELSKSVSG 135
                 33334444444444 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 1.1
         CLZ  26 qkeleekverLessLeaLqtrl 47 
                 + + +  + ++es Le+++tr 
  EEA19124.1 159 AGQGNAYLAKIESVLEQIETRP 180
                 5555667889999999999985 PP

>> ADIP  Afadin- and alpha -actinin-Binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.8   3.6e-05     0.054      64     127 ..      26      89 ..      16      98 .. 0.91

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 3.6e-05
        ADIP  64 kleaeierlqskierlktqleqlerelalvqakerqlekklktleqklknekeelqrlknalqq 127
                 +l+ e  +l  +i+ ++tql ++  + +++++++ +l   +ktl++ + ++k e++  +++l +
  EEA19124.1  26 QLRREHVHLVDRIDDMSTQLVSYNDKSQTYEQNLSTLDGLVKTLQAENYTLKNEVTLVRTKLTA 89 
                 788899999**********************************************999998876 PP

>> Cnn_1N  Centrosomin N-terminal motif 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.1      0.27     4e+02      36      68 ..      36      68 ..      24      71 .. 0.60
   2 ?   11.9   0.1   0.00012      0.19      10      68 ..      67     135 ..      61     140 .. 0.88

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.27
      Cnn_1N 36 eqkeellkenielkveveslqkelkekkkllre 68
                + ++++  +++   ++ ++ ++ l +++ l++ 
  EEA19124.1 36 DRIDDMSTQLVSYNDKSQTYEQNLSTLDGLVKT 68
                455666666666666666666666666666665 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 0.00012
      Cnn_1N  10 dkLkKENFdLKLriyfLeerleklse..........eqkeellkenielkveveslqkelkekkkllre 68 
                 ++L+ EN+ LK ++   + +l+++ e          +  +++++   +lk e   +  ++ e+ k++  
  EEA19124.1  67 KTLQAENYTLKNEVTLVRTKLTARIEgisqqitaflSGDNAAIDATKQLKLEFRAMGLQMSELSKSVSG 135
                 789***********8888888877777787******99*******************999999998865 PP

>> FlaC_arch  Flagella accessory protein C (FlaC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.1    0.0015       2.2       5      33 ..      55      83 ..      51     101 .. 0.90
   2 ?    4.0   0.0     0.044        66      15      41 ..     118     144 ..     112     145 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0015
   FlaC_arch  5 lEnklsklsteletvkkeneelsksveel 33
                 E+ ls l+  ++t+++en  l+++v+ +
  EEA19124.1 55 YEQNLSTLDGLVKTLQAENYTLKNEVTLV 83
                59***********************9865 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.044
   FlaC_arch  15 eletvkkeneelsksveelkenVkdll 41 
                 e+  +  +++elsksv  lk ++  ++
  EEA19124.1 118 EFRAMGLQMSELSKSVSGLKGEIASVI 144
                 555666699**********99998887 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.4   0.00088       1.3       7      55 ..      35      83 ..      30     107 .. 0.53
   2 ?    2.1   0.0       0.2   2.9e+02       4      37 ..     113     146 ..     109     156 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00088
                HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHXXX CS
        YabA  7 fdkleeleeqleelleeleelkeelaelleenaeLeleneklrerleee 55
                +d+++++++ql + +++ ++ +++l++l    ++L++en +l+++++  
  EEA19124.1 35 VDRIDDMSTQLVSYNDKSQTYEQNLSTLDGLVKTLQAENYTLKNEVTLV 83
                5566666666655555555555555555555555555555555544222 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.2
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        YabA   4 kelfdkleeleeqleelleeleelkeelaellee 37 
                 k+l  +++++  q++el+++++ lk e+a+++ +
  EEA19124.1 113 KQLKLEFRAMGLQMSELSKSVSGLKGEIASVIAQ 146
                 5677788999999************999998765 PP

>> Taxilin  Myosin-like coiled-coil protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   9.5e-05      0.14      39     136 ..      29     126 ..      12     135 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 9.5e-05
     Taxilin  39 kqlkklkkkleqlqkekeqlqaelskaalaksKLekLcRelqkqnkklkeeskqrareeeekrkelaekfqakLkdiqaqieekserneklreenael 136
                 +++ +l  + + +  +  +  ++ + + +  s L+ L + lq +n +lk+e + + ++  ++ + ++++  a L+  +a i++ ++ + ++r +  ++
  EEA19124.1  29 REHVHLVDRIDDMSTQLVSYNDKSQTYEQNLSTLDGLVKTLQAENYTLKNEVTLVRTKLTARIEGISQQITAFLSGDNAAIDATKQLKLEFRAMGLQM 126
                 55666666666666666667777778889999********************9999999999999999988888877777777777666666665555 PP

>> Retrotrans_gag  Retrotransposon gag protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.2       0.2     3e+02      13      93 ..      22     104 ..      16     106 .. 0.71
   2 ?    8.8   0.0    0.0013       1.9      52      95 ..     245     288 ..     239     289 .. 0.90

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.2
  Retrotrans_gag  13 swlkslvarsidasesWkdlkkaflktflpserkdqleeelsslrQgtesvreYvtrfktladqldevlte.....eakiekflaG 93 
                      w+ +l+++++  ++  +d+++++ + + +s++++q  + l  l + t   + Y+ + + ++ + +  lt       ++i++fl G
      EEA19124.1  22 LWAYQLRREHVHLVDRIDDMSTQLVSYNDKSQTYEQNLSTLDGLVK-TLQAENYTLKNEVTLVRTK--LTAriegiSQQITAFLSG 104
                     6777888888888888889999999999999999999888999998.8888888766554444444..222333446677777666 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0013
  Retrotrans_gag  52 elsslrQgtesvreYvtrfktladqldevlteeakiekflaGLn 95 
                      +++++Q+ +++++Y+   + l+ ql++  +e  ++e+f +G++
      EEA19124.1 245 IFQQIHQNGRTISDYLVFTSNLRIQLPRRKQEGHIVEAFFDGIT 288
                     589**************99********98899999****99986 PP

>> SOGA  Protein SOGA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   0.3     0.015        22      19      77 ..      27      86 ..      24      93 .. 0.74
   2 ?    9.5   0.2    0.0014       2.1      25      89 ..      68     137 ..      62     141 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.015
        SOGA 19 lrrslseleeenkqlteeLnkyksklgeeessleeee.eassdsskeaelkeeLklarlq 77
                lrr+ ++l +  + + ++L  y  k ++ e++l++ +   ++ ++++ +lk+e+ l+r +
  EEA19124.1 27 LRREHVHLVDRIDDMSTQLVSYNDKSQTYEQNLSTLDgLVKTLQAENYTLKNEVTLVRTK 86
                788888888889999999999988888888888776633444455667788888888765 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.0014
        SOGA  25 eleeenkqlteeLnkyksklgeeessleeee.....eassdsskeaelkeeLklarlqineLsgkvvkLq 89 
                  l+ en  l++e++  ++kl ++ + ++++      + +++   +++lk e ++  lq++eLs+ v  L+
  EEA19124.1  68 TLQAENYTLKNEVTLVRTKLTARIEGISQQItaflsGDNAAIDATKQLKLEFRAMGLQMSELSKSVSGLK 137
                 6889999*****99999999999888887657888766777788999*****************998886 PP

>> JIP_LZII  JNK-interacting protein  leucine zipper II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.1     0.058        87      30      69 ..      33      72 ..      29      74 .. 0.90
   2 ?    7.1   0.2    0.0041       6.2      11      59 ..      70     115 ..      65     127 .. 0.69
   3 ?   -1.8   0.0       2.4   3.6e+03      36      55 ..     127     146 ..     124     148 .. 0.80

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.058
    JIP_LZII 30 dLIarvdeLtsereiLreEleslqkakerlesrikelEee 69
                +L+ r+d+++++  + ++  ++ ++++++l   +k l++e
  EEA19124.1 33 HLVDRIDDMSTQLVSYNDKSQTYEQNLSTLDGLVKTLQAE 72
                89**************999999999999999988888766 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0041
    JIP_LZII  11 ikENteLletknaLnvvkddLIarvdeLtsere.iLreEleslqkakerl 59 
                  +EN  L   kn +  v+  L ar++ ++++ +  L+ ++ ++  a ++l
  EEA19124.1  70 QAENYTL---KNEVTLVRTKLTARIEGISQQITaFLSGDNAAID-ATKQL 115
                 5555554...899999*************998834555555444.44444 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 2.4
    JIP_LZII  36 deLtsereiLreEleslqka 55 
                  eL++  + L+ E+ s+ ++
  EEA19124.1 127 SELSKSVSGLKGEIASVIAQ 146
                 68999999999999998765 PP

>> ATG16  Autophagy protein 16 (ATG16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   2.4   0.00026      0.39      83     155 ..      24     114 ..       2     146 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00026
       ATG16  83 laqlreelaelyksrgelaqrllelneelqkleeklkedeerlaeleaeraaletklkdreeelrekeklvq..................d 155
                  +qlr e   l  +  +++++l++ n++ q+ e++l++ +  ++ l+ae+ +l+ ++   + +l  + + +                   +
  EEA19124.1  24 AYQLRREHVHLVDRIDDMSTQLVSYNDKSQTYEQNLSTLDGLVKTLQAENYTLKNEVTLVRTKLTARIEGISqqitaflsgdnaaidatkQ 114
                 3689999999999999**************************************9998777776665555544444555555554444444 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.8   0.00035      0.53      30      99 ..      31     100 ..      24     139 .. 0.85
   2 ?   -2.6   0.0       3.8   5.7e+03      39      55 ..     168     184 ..     161     231 .. 0.43

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00035
                 CCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC CS
   Fib_alpha  30 ekdvkkdlekleneleeisnstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketida 99 
                 + ++ ++++++  +l ++++++++ e+  ++++  ++  q+++   +n ++ ++++l  +i+ + ++i+a
  EEA19124.1  31 HVHLVDRIDDMSTQLVSYNDKSQTYEQNLSTLDGLVKTLQAENYTLKNEVTLVRTKLTARIEGISQQITA 100
                 5567789*********************************999999*******************99976 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 3.8
                 CCCCCCCCCCCHHHHHH CS
   Fib_alpha  39 kleneleeisnstkeae 55 
                 k+e+ le+i+ + k + 
  EEA19124.1 168 KIESVLEQIETRPKCIV 184
                 45555555544443333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (352 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       795  (0.0443416); expected 358.6 (0.02)
Passed bias filter:                      594  (0.0331307); expected 358.6 (0.02)
Passed Vit filter:                        90  (0.0050198); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.71u 0.36s 00:00:01.06 Elapsed: 00:00:00.54
# Mc/sec: 1958.95
//
Query:       EEA19125.1  [L=231]
Description: fumarylacetoacetate hydrolase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.2e-53  179.5   0.0      9e-53  179.2   0.0    1.0  1  FAA_hydrolase  Fumarylacetoacetate (FAA) hydrolase family


Domain annotation for each model (and alignments):
>> FAA_hydrolase  Fumarylacetoacetate (FAA) hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  179.2   0.0     5e-57     9e-53       1     217 [.      11     214 ..      11     219 .. 0.92

  Alignments for each domain:
  == domain 1  score: 179.2 bits;  conditional E-value: 5e-57
                    .EEEEEEE--SHHHHHTTT.-SS-EEEEEEGGGE.EETTE..EE-TT.SSSS-EE......EEEEEEEESS-B--T..--HHHHHTTEEEEEEEEE CS
  FAA_hydrolase   1 kivcdglnyaehvreagkaaeeppdrhiplepvfflkrasslvgpgd.pirrPagsekldyEvELavvigkplrev..lsveeAedaiaGytllnD 93 
                    ki+c+g+nya+h++e++++    p+     +p fflk++ssl  pg+ p+++P+g++ ++yEvEL++vigk lr++   + + A d i+ y+l+ D
     EEA19125.1  11 KIICIGRNYADHITELNSL---TPK-----QPFFFLKPTSSLLLPGQgPVLLPKGVN-VHYEVELGLVIGKTLRDLdpEDHQGALDSISSYLLAID 97 
                    69*************9755...344.....566*********9998758******77.9****************965556779************ PP

                    EE-SBGGG---..HHHHHHTGGGEEEEEE-B--B-.STT---SS-EEEEEETTEEEEEEEGGGTTTSHHHHHHHHHHHH-B-TT-EEEEEES.... CS
  FAA_hydrolase  94 vsaRdlqaeek.aplgwflgksfdtftpiGpwivtpdeledpedlelrlrvngeevqdsntkdmifspaeliahlsagltLepGdliltGTpsgvg 188
                    ++aR++q+e+k + l+w  +k+fdtf+pi+  i ++++++dp++  lrl+v ++++q  nt+ m++++++++a +s+++tLe Gdl+ltGTp+gvg
     EEA19125.1  98 MTARNVQDEAKrKGLPWSIAKGFDTFCPISNLI-PKSAIPDPHNAFLRLSVGDQVRQADNTNLMLYQIPRQLADISRVMTLEEGDLVLTGTPKGVG 192
                    ***********8888******************.************************************************************99 PP

                    ...S--EE--TT-EEEEEETTTEEEEEEE CS
  FAA_hydrolase 189 aeeeslkflkdgDeveveieglGelrnrV 217
                    +       +kdg+++++eie  G++  r+
     EEA19125.1 193 Q-------VKDGEVITAEIEVDGKQVERI 214
                    4.......***********9878877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (231 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       357  (0.0199119); expected 358.6 (0.02)
Passed bias filter:                      333  (0.0185733); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1518.56
//
Query:       EEA19126.1  [L=826]
Description: checkpoint protein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.3e-48  163.0   0.0    1.4e-47  162.3   0.0    1.3  1  Pkinase         Protein kinase domain
    2.5e-18   66.3   0.0    3.8e-18   65.7   0.0    1.2  1  Pkinase_Tyr     Protein tyrosine kinase
    0.00063   19.4   0.2     0.0012   18.5   0.2    1.4  1  RIO1            RIO1 family
  ------ inclusion threshold ------
      0.012   14.9   0.1      0.022   14.1   0.1    1.4  1  Kdo             Lipopolysaccharide kinase (Kdo/WaaP) family
      0.013   15.4   0.1      0.087   12.7   0.1    2.2  2  APH             Phosphotransferase enzyme family
      0.077   11.8   0.1      0.077   11.8   0.1    2.2  3  Pkinase_fungal  Fungal protein kinase
       0.15   11.4   0.0       0.41    9.9   0.0    1.7  2  Kinase-like     Kinase-like


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  162.3   0.0   5.5e-51   1.4e-47       2     260 ..     485     761 ..     484     764 .. 0.85

  Alignments for each domain:
  == domain 1  score: 162.3 bits;  conditional E-value: 5.5e-51
                 EEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHS.CTTB--EEEEEEE..SSEEEEEEE--TTEBHHHHHH.....HH CS
     Pkinase   2 ekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklk.hpnivrlyevfee..kdelylvleyveggeladlle.....rk 92 
                 +++  +G+G++++Vy+++ +e+ ki+A+K+++ e+a+  +   +  Ei +lk+l+  +++vrl+++  +  k++l +++e+ e + l+++l      ++
  EEA19126.1 485 TRMDCIGRGGTSRVYRVM-AENYKIFALKRVNLEDADRVTLAGYKGEIDLLKRLEnVDRVVRLFDWEINmeKHTLSVLMEIGESD-LEKILAyrlnaDD 581
                 56778*************.8***********************************9*******9876554488899*****9976.7777766666666 PP

                 SS--HHHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCS...BCTTTSCGGGS-HHHH..............TTSCB CS
     Pkinase  93 gslseeeakkiakqilegleylHskgiiHrDlKpeNiLidekgelKitDFGlakelesssk...ltsfvgtseYlAPEvl..............keney 174
                  +++++ +++++k++le ++ +H+++i+H DlKp+N+L+  +g lKi+DFG+a+ ++ ++     +++vgt++Y++PE l              k  + 
  EEA19126.1 582 AIFDSSFTRFYWKEMLECVQAVHKHNIVHSDLKPANFLLV-QGRLKIIDFGIANAISDDTVnvhREHQVGTPNYMSPEALidsnaasglpasvgKMMKL 679
                 77999***********************************.****************99888999***************9*99998888877555777 PP

                 SHHHHHHHHHHHHHHHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCT.SHH...HHHTTS......-HHHHHHHHHHT-SSGCCSTTHHHHHT CS
     Pkinase 175 skkvDvWslGvilyelltgkppfsgekgkekvekeldqlekilkilg.etkeklpeasei......seeakdllkkllkkdpkkRltaeellq 260
                 +k++DvWslG+ily++++g+ppf+   +  k+++       i+ i + +   ++p+          ++ +++ +k++l++d++ R+t eell+
  EEA19126.1 680 GKPSDVWSLGCILYKMVYGQPPFA---RIAKYYER------IMAIPNpKIPIEFPQF--AvggvtvPPGLLRTMKRCLQRDQTLRPTTEELLS 761
                 ************************...33333333......4444442212222222..2445566************************997 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.7   0.0   1.5e-21   3.8e-18       6     256 ..     489     760 ..     484     762 .. 0.83

  Alignments for each domain:
  == domain 1  score: 65.7 bits;  conditional E-value: 1.5e-21
                  EEEEESSEEEEEEEEETTTTSSEEEEEEEEES.TTSSHHHHHHHHHHHHHHHTS.-BTTB--EEEEEE..SSSSEEEEEE--TTEBHHHHHHHT...C CS
  Pkinase_Tyr   6 klGeGafGkVvegtlkgekekkevkVavKtlk.eeateeekeelleeakimkkl.khpnivkllgvct..keepllivteyvkgGdLlkfLrkk...e 96 
                   +G+G  ++V++  ++     +    a+K ++ e+a++ + +    e++++k+l + +++v+l  + +  ++++l +++e   + dL+k L  +   +
   EEA19126.1 489 CIGRGGTSRVYRVMAE-----NYKIFALKRVNlEDADRVTLAGYKGEIDLLKRLeNVDRVVRLFDWEInmEKHTLSVLMEI-GESDLEKILAYRlnaD 580
                  6899999999999888.....6777899999636777777888888********99********99885455556777775.5669999998775534 PP

                  TTTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEETTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSE............. CS
  Pkinase_Tyr  97 kekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsenkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekk............. 181
                  ++ ++ + +  +  ++ + ++ ++++++vH dl   N Ll  +   ki DfG+a++i++d   v++e++    ++m+pE+l +++             
   EEA19126.1 581 DAIFDSSFTRFYWKEMLECVQAVHKHNIVHSDLKPANFLLV-QGRLKIIDFGIANAISDDTVNVHREHQVGTPNYMSPEALIDSNaasglpasvgkmm 677
                  5555555555567799************************9.7789***********9999999999999***********999999*********99 PP

                  .EEHHHHHHHHHHHHHHHHTTSSGTTTTS.HHHHHHHHH.HTTEES-BBT......TSBHHHHHHHHHHT-SSGGGS--HHHHH CS
  Pkinase_Tyr 182 .ftsksDvWsfGvllwEiftlgespypgl.kneevlekl.kegkrlekpe......kcpeelyelmkkcweedpeeRptfselv 256
                   + + sDvWs G +l+ ++  g+ p++++ k  e + ++ + +  +e p+      ++p+ l + mk+c+++d++ Rpt +el+
   EEA19126.1 678 kLGKPSDVWSLGCILYKMVY-GQPPFARIaKYYERIMAIpNPKIPIEFPQfavggvTVPPGLLRTMKRCLQRDQTLRPTTEELL 760
                  99999************998.*******97666666666477777888873333335689999****************99986 PP

>> RIO1  RIO1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.2   4.7e-07    0.0012      76     150 ..     551     631 ..     498     641 .. 0.74

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 4.7e-07
                 EEEETTEE..EEE--E..ETTEEGGBHHHCG-..HHHHHHHHHHHHHHHHHHHHTSTEEESS-STTSEEEETTEEEE--GT CS
        RIO1  76 ielkrhvl..vmefig..edgvaapklkdvee..eeeaeelyeevleemrklykeaglvHaDLSeyNvlvdedkvviIDvs 150
                 i++++h l  +me  +   +++ a++l+  +   ++  ++ y++ + e  ++++++++vH DL   N l+ ++++ iID++
  EEA19126.1 551 INMEKHTLsvLMEIGEsdLEKILAYRLNADDAifDSSFTRFYWKEMLECVQAVHKHNIVHSDLKPANFLLVQGRLKIIDFG 631
                 4555665332666554223466778888777447888899999888889999***************************97 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.1   8.8e-06     0.022     103     167 ..     567     631 ..     523     644 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 8.8e-06
         Kdo 103 qdLedllakwae.....laeelkrallkavgrliaklhragvnHadlyaknillqqeeeeeaeiwliDld 167
                 +dLe++la   +     ++ + +r  +k+    ++  h+ ++ H dl + n+ll q+      + +iD+ 
  EEA19126.1 567 SDLEKILAYRLNaddaiFDSSFTRFYWKEMLECVQAVHKHNIVHSDLKPANFLLVQGR-----LKIIDFG 631
                 6777777643323457799999********************************9995.....8899985 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.0      0.22   5.5e+02       8      63 ..     493     552 ..     490     581 .. 0.71
   2 ?   12.7   0.1   3.4e-05     0.087     142     196 ..     585     633 ..     524     636 .. 0.66

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.22
                 .SSCEEEEEEETT.--EEEEEE-TTS-HHHHH....HHHHHHHHHHHTT-B--B-CTTBS- CS
         APH   8 gasnrtylvttpa.gryvlrrnpparaaeeir....revallrlLakagvpvPevlagdtd 63 
                 g  +r+y+v  ++ + ++l+r++ ++a++ +     +e +ll+ L++ +  v ++++++ +
  EEA19126.1 493 GGTSRVYRVMAENyKIFALKRVNLEDADRVTLagykGEIDLLKRLENVDR-VVRLFDWEIN 552
                 555679*******999*****99996666665544466667777766655.7788876544 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 3.4e-05
                 CCHHHHHHHHHHHHHHHH--SSS-EEEE-SS-SGGGEEEC..TTEEEEE---TT- CS
         APH 142 ldlleeleeqvlaalaallpgelptvllHgDlhpgNllvdpddgrvtGviDfeda 196
                 +     +++  + ++++ +++  ++ ++H Dl+p N+l+   +gr+  +iDf+ a
  EEA19126.1 585 DS---SFTRFYWKEMLECVQAVHKHNIVHSDLKPANFLLV--QGRL-KIIDFGIA 633
                 33...445558888888888888999**************..8998.8****976 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.1   0.5         2     5e+03     238     266 ..     276     306 ..     259     364 .. 0.51
   2 ?   -1.6   0.1      0.34   8.7e+02     132     206 ..     468     547 ..     451     558 .. 0.56
   3 ?   11.8   0.1     3e-05     0.077     322     386 ..     603     660 ..     594     665 .. 0.89

  Alignments for each domain:
  == domain 1  score: -4.1 bits;  conditional E-value: 2
  Pkinase_fungal 238 kvvsssssqe..lsskaevklkksesskkve 266
                     ++  +++++e  +ss +  +++++ ss++v+
      EEA19126.1 276 QSDRHTPEREmrQSSPRYAREENEASSRPVR 306
                     2222222222211111112222222222222 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.34
  Pkinase_fungal 132 aeeeketeklele.eplarqraivgRg..TtcwrarkegergkeyvvKdsW.rdaer......ksEaelLkkaeergvegvarlv 206
                      +++k+  +++++ + ++r ++i gRg   +++r+  e+ +   + +K +  +da+r      k E +lLk+   ++v  v+rl+
      EEA19126.1 468 SQSRKKRSQVTINhKAFTRMDCI-GRGgtSRVYRVMAENYK--IFALKRVNlEDADRvtlagyKGEIDLLKRL--ENVDRVVRLF 547
                     34456666777774555555555.55521368998887666..355554321333332222214577777777..6666666665 PP

  == domain 3  score: 11.8 bits;  conditional E-value: 3e-05
  Pkinase_fungal 322 LflkagiLHrDiSenNilitdskkegerkglLiDLDlakelsddssesgarertGTleFmaievl 386
                      + k +i+H D    N l++      + +  +iD+ +a  +sdd+ + ++++++GT+++m+ e l
      EEA19126.1 603 VH-KHNIVHSDLKPANFLLV------QGRLKIIDFGIANAISDDTVNVHREHQVGTPNYMSPEAL 660
                     45.99***************......78999************9999999**********98776 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       1.6   4.1e+03      46      90 ..      83     126 ..      78     137 .. 0.79
   2 ?    9.9   0.0   0.00016      0.41     154     255 ..     597     707 ..     586     750 .. 0.77

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 1.6
  Kinase-like  46 llpseaskkdlerlkeqelairllrgknpeqAkdhlrlllpfdlv 90 
                  +++  + +++l++ + + l i+  r  +  + ++h+r+  p+d  
   EEA19126.1  83 VMETSPHQQQLQQTSAKRLSIAA-RDFSSARPERHVRVASPHDSS 126
                  57778889999999999999988.777888888999999999865 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.00016
  Kinase-like 154 irlaanLqakglvhgkftvdnllldekgglmlggftaLvragtkvvl..seve...kgfaPpE.llgsrgg....ytrknktkmthkldaWqlGlviy 241
                  +  ++  +++ +vh ++++ n+ll  +g+l++ +f+      +  v    e +     +  pE l+ s +         + +k   + d+W lG   y
   EEA19126.1 597 LECVQAVHKHNIVHSDLKPANFLLV-QGRLKIIDFGIANAISDDTVNvhREHQvgtPNYMSPEaLIDSNAAsglpASVGKMMKLGKPSDVWSLGCILY 693
                  5678999***************997.59******986655555444212333355634555551554444344555566788889999********** PP

  Kinase-like 242 riwclklPltlate 255
                   +   + P+  +++
   EEA19126.1 694 KMVYGQPPFARIAK 707
                  *9998888887776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (826 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       642  (0.0358079); expected 358.6 (0.02)
Passed bias filter:                      379  (0.0211389); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.73u 0.30s 00:00:01.03 Elapsed: 00:00:00.48
# Mc/sec: 5131.10
//
Query:       EEA19127.1  [L=433]
Description: cell wall protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.099   13.3   5.0        0.8   10.4   1.2    3.0  2  DUF4728   Domain of unknown function (DUF4728)


Domain annotation for each model (and alignments):
>> DUF4728  Domain of unknown function (DUF4728)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.1    0.0079   1.4e+02      16      55 ..     184     223 ..     172     258 .. 0.84
   2 ?   10.4   1.2   4.5e-05       0.8      23      77 ..     298     352 ..     279     359 .. 0.81

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.0079
     DUF4728  16 LilGtkkerhllLlPWLinslvslvleigilvalvllvsv 55 
                 L+ ++  + + ++  WL  s ++l ++  + + l+l ++v
  EEA19127.1 184 LVTALTADVKAVITAWLASSECGLPIDLKVAIGLWLEAEV 223
                 7888888889999************999999999987765 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 4.5e-05
     DUF4728  23 erhllLlPWLinslvslvleigilvalvllvsvieakidrlialliifflllvLn 77 
                 e    L  WL   ++sl++e    v l+l ++v e + ++++a+  i +l + ++
  EEA19127.1 298 EAVEKLTVWLLSTGCSLTVELKAAVLLWLHARVAEVESVSVLAAADIATLTTWIE 352
                 55566889*****************************999999998888877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (433 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       422  (0.0235373); expected 358.6 (0.02)
Passed bias filter:                      204  (0.0113782); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.70u 0.34s 00:00:01.04 Elapsed: 00:00:00.59
# Mc/sec: 2213.55
//
Query:       EEA19128.1  [L=357]
Description: PWI domain mRNA processing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-29  101.9   0.0    3.1e-29  101.1   0.0    1.4  1  PWI       PWI domain


Domain annotation for each model (and alignments):
>> PWI  PWI domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.1   0.0   1.7e-33   3.1e-29       1      72 []      31     102 ..      31     102 .. 0.98

  Alignments for each domain:
  == domain 1  score: 101.1 bits;  conditional E-value: 1.7e-33
         PWI   1 dvlkpWIakkitellgfeDdvvieyvlnlLeeekeldpkklqinltgfLekeaekFvkeLWelllsaqssee 72 
                 +v+k+WIa k++ellg eDdv+ie+++ lLe+++++++k lqi+ltgfL+k+++kF++eLW+l+lsaqss++
  EEA19128.1  31 EVMKKWIAGKLSELLGDEDDVIIELCFGLLESSRYPNIKALQIQLTGFLDKDTPKFCQELWNLCLSAQSSPQ 102
                 79*******************************************************************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (357 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       547  (0.0305092); expected 358.6 (0.02)
Passed bias filter:                      381  (0.0212505); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.32s 00:00:01.00 Elapsed: 00:00:00.56
# Mc/sec: 1918.16
//
Query:       EEA19129.1  [L=98]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (98 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       453  (0.0252663); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.58u 0.33s 00:00:00.90 Elapsed: 00:00:00.57
# Mc/sec: 518.70
//
Query:       EEA19130.1  [L=521]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-08   34.2   9.2    3.5e-08   33.4   9.2    1.4  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.4   9.2     2e-12   3.5e-08       2      35 ..      10      43 ..       9      46 .. 0.93

  Alignments for each domain:
  == domain 1  score: 33.4 bits;  conditional E-value: 2e-12
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCT CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfyse 35
                +C +Crk+K+KCd+++P+C++C++  ++C+ y++
  EEA19130.1 10 GCHTCRKRKIKCDGGRPTCKQCARGLWTCEGYNR 43
                7****************************98876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (521 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       517  (0.028836); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.73u 0.31s 00:00:01.04 Elapsed: 00:00:00.56
# Mc/sec: 2821.33
//
Query:       EEA19131.1  [L=272]
Description: short-chain dehydrogenase/oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.1e-35  120.4   0.0    8.2e-35  120.0   0.0    1.1  1  adh_short        short chain dehydrogenase
    6.8e-19   68.4   0.0    8.4e-19   68.0   0.0    1.1  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    8.5e-08   32.3   0.1    1.1e-07   31.9   0.1    1.2  1  KR               KR domain
    0.00025   21.0   0.0    0.00037   20.4   0.0    1.4  1  NAD_binding_10   NAD(P)H-binding
    0.00032   20.8   0.0    0.00051   20.1   0.0    1.3  1  Shikimate_DH     Shikimate / quinate 5-dehydrogenase
    0.00041   20.0   0.1    0.00074   19.2   0.1    1.4  1  ApbA             Ketopantoate reductase PanE/ApbA
     0.0008   19.7   0.1     0.0014   18.9   0.1    1.4  1  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma
     0.0014   18.1   0.0      0.006   16.1   0.0    1.8  2  Epimerase        NAD dependent epimerase/dehydratase family
  ------ inclusion threshold ------
      0.079   13.1   0.0       0.14   12.3   0.0    1.3  1  NAD_binding_2    NAD binding domain of 6-phosphogluconate deh


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  120.0   0.0   4.1e-38   8.2e-35       1     191 [.       7     203 ..       7     206 .. 0.91

  Alignments for each domain:
  == domain 1  score: 120.0 bits;  conditional E-value: 4.1e-38
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCSHH CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfselsee 99 
                 k +l++Ga+sGIG a+a +l+++G kvv+v+r++e+l  ++k+l++  +k  a+q+D+t+ ++++++ +k+ +++  +d+++ N Gi++s +f++ +  
  EEA19131.1   7 KKALIIGATSGIGEALAIKLVANGSKVVLVGRRQERLDSLVKQLGS--DKSSAVQFDITKLQDISDFASKVTSEHPDIDAVILNSGIQRSFNFAQPETV 103
                 689******************************************7..6899***********************************888777665444 PP

                 H...HHHHHHHHTHHHHHHHHHHHHHHH.HCTTEEEEEEEEGGGTSB.-TTBHHHHHHHHHHHHHHHHHHHHHGGGT...EEEEEEEESSBSSHHHHHH CS
   adh_short 100 e...wervievNltgvflltravlpaml.kqssGrIvnvsSvagkvp.vagvaaYsAsKaavagltrslakelaptg...irvnavaPGlvdTdmakel 190
                 +   +++ + +N+t++++lt a+lp +  ++   + v +s + g  p v+ +  Y AsKaa++++   ++++l+++    ++v+ v P++v+T++  e+
  EEA19131.1 104 DlgmVQEELTTNYTSIIHLTMAFLPFLQaQKTTTHLVYISATLGIIPtVIRTGGYNASKAALHHWLLVFREQLKQQPdnqVQVVEVFPPAVQTELHDER 202
                 43348999******************997788899*********7662678899*******************9976667**************99876 PP

                 C CS
   adh_short 191 r 191
                  
  EEA19131.1 203 H 203
                 5 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.0   0.0   4.2e-22   8.4e-19       1     183 [.      13     203 ..      13     225 .. 0.80

  Alignments for each domain:
  == domain 1  score: 68.0 bits;  conditional E-value: 4.2e-22
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSE...EEE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EG.CSS-GGGH-HH CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneeakkrveelaeelgae...vlecDVtdeeqvealveevvekfgklDilvnnagiapk.lkgpfletsre 93 
                   Ga sgIG+a+A +l ++G +vvl+ +++e+   +++l+++lg++   +++ D+t+ +++ +++++v++++  +D ++ n gi ++   ++ ++++  
    EEA19131.1  13 GATSGIGEALAIKLVANGSKVVLVGRRQER---LDSLVKQLGSDkssAVQFDITKLQDISDFASKVTSEHPDIDAVILNSGIQRSfNFAQPETVDLG 106
                   999*********************999998...777777777554437*************************************877777889*** PP

                   HHHHHHHHHTHHHHHHHHHHHHHCTSC...CEEEEEEEGGGTSB.STTTTHHHHHHHHHHHHHHHHHHHHGG...GTEEEEEEEE--BHCTGGGGST CS
  adh_short_C2  94 efdraldvnlyslfllakaalplmkeg...gsivnlssvgaerv.vpnynaygaaKaalealtrylAvelgp...kgiRvNavspgpikTlaasgik 183
                    +++ l +n +s+++l+ a+lp ++++     +v +s + + +  v  +  y+a+Kaal++    +  +l +   ++++v  v p +++T++ ++ +
    EEA19131.1 107 MVQEELTTNYTSIIHLTMAFLPFLQAQkttTHLVYISATLGIIPtVIRTGGYNASKAALHHWLLVFREQLKQqpdNQVQVVEVFPPAVQTELHDERH 203
                   **********************8888834455555555544444244455**********9887777777664446888888888888888877665 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.9   0.1   5.7e-11   1.1e-07       4     122 ..      10     125 ..       8     179 .. 0.74

  Alignments for each domain:
  == domain 1  score: 31.9 bits;  conditional E-value: 5.7e-11
                 EEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT... CS
          KR   4 litGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdkllee... 99 
                 li+G++ g+G +la  l+++g  ++vl++R+   +e+ ++l+++l +   + ++v+ D+++ ++++   +++++e+p i  vi   g+ r   +++   
  EEA19131.1  10 LIIGATSGIGEALAIKLVANGS-KVVLVGRR---QERLDSLVKQLGSD--KSSAVQFDITKLQDISDFASKVTSEHPDIDAVILNSGIQRSFNFAQpet 102
                 9*******************96.6899****...34445577777775..456899*******************************998776665111 PP

                 --HHHHHHHHTTTTHHHHHHHHH CS
          KR 100 mtaedleqvlapKvkGawnLhel 122
                 ++  ++++ l    + + +L  +
  EEA19131.1 103 VDLGMVQEELTTNYTSIIHLTMA 125
                 33344455555555555555555 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.0   1.9e-07   0.00037       1      73 [.      13      94 ..      13     146 .. 0.81

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 1.9e-07
                    TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHH...CTTTCEEEE--TT-CCHHHHHHT.......T-SEEEES---TCC CS
  NAD_binding_10  1 GAtGkvGrllvkellargghevtalvRnpeklaele...aeeglevvegdvtdvedlaealk.......gadaVvsalggggk 73
                    GAt ++G +l+ +l+a+g  +v+++ R++e+l++l     +++ ++v+ d+t+ +d+ +  +       ++daV+ + g +++
      EEA19131.1 13 GATSGIGEALAIKLVANG-SKVVLVGRRQERLDSLVkqlGSDKSSAVQFDITKLQDISDFASkvtsehpDIDAVILNSGIQRS 94
                    9****************5.9************98762333478999**99997776666555555888899999999887766 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   0.0   2.6e-07   0.00051      13      67 ..       7      61 ..       3     105 .. 0.86

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 2.6e-07
                  -EEEEES-SH.HHHHHHHHHHCCT-CEEEEEESSHHHHHHHHHHHT.ET-EEEEGC CS
  Shikimate_DH 13 kkvlliGaGe.maelvakhLlakgvkkvvvaNRtlerakelaeelkgeeiealkle 67
                  kk+l+iGa   ++e +a +L+a+g k vv ++R +er ++l+++l++++++a++++
    EEA19131.1  7 KKALIIGATSgIGEALAIKLVANGSK-VVLVGRRQERLDSLVKQLGSDKSSAVQFD 61
                  799****97548899999*****999.999***************99999888875 PP

>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   0.1   3.7e-07   0.00074       3      74 ..      11      87 ..       9      88 .. 0.79

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 3.7e-07
                EES-S.HHHHHHHHHHHHHTHCEEEE-SCH.HHHH.HHHHCEEEEETT..CEEEEEECEEECCHSCCCCS-ESEEEE CS
        ApbA  3 ilGaG.aiGsllaakLakagadvtlilrsr.rlea.lkknGlrltseg..geeilrppealsaeekselepidlviv 74
                i+Ga  +iG  la kL ++g +v+l++r++ rl++ +k+ G++ +s      ++l++   ++++ +se  +id vi+
  EEA19131.1 11 IIGATsGIGEALAIKLVANGSKVVLVGRRQeRLDSlVKQLGSDKSSAVqfDITKLQDISDFASKVTSEHPDIDAVIL 87
                7777526****************************999999999999955555555555555446777788888875 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.1   6.9e-07    0.0014       2      63 ..      10      68 ..       9      87 .. 0.90

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 6.9e-07
                     EEE--.SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHH CS
  Sacchrp_dh_NADP  2 liiGa.GsvGqavaellarhfdvdaeitvadrskeklealaakalgvrfeaialdaenyeavL 63
                     liiGa  ++G+a+a +l+++++   ++++++r +e+l+ l++++ + + +a+++d+ + ++ +
       EEA19131.1 10 LIIGAtSGIGEALAIKLVANGS---KVVLVGRRQERLDSLVKQLGSDKSSAVQFDITKLQD-I 68
                     89******************98...6******************99999999999998877.4 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0     3e-06     0.006       1      76 [.       9      90 ..       9     107 .. 0.71
   2 ?   -0.6   0.0      0.36   7.2e+02     140     160 ..     156     176 ..     145     198 .. 0.88

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 3e-06
                EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC.........EEEE--TT-HHHHHHHHH....HH.T-SEEEE--S--- CS
   Epimerase  1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl.........elveldltdrsalerlfk....ee.qpdavihlAavgg 76
                +l++Gat  iG al+ +l ++g +v+ + r++++  +     l         + v+ d+t+ +++ ++ +    e+ ++davi+    +g
  EEA19131.1  9 ALIIGATSGIGEALAIKLVANGSKVVLVGRRQERLDS-----LvkqlgsdksSAVQFDITKLQDISDFASkvtsEHpDIDAVILN---SG 90
                59****************************9433332.....2334689999788888887776665544111044556666655...44 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.36
                 SHHHHHHHHHHHHHHHHHHHH CS
   Epimerase 140 spYaaaKlageklveayaaqy 160
                   Y a+K+a ++ +  +++q 
  EEA19131.1 156 GGYNASKAALHHWLLVFREQL 176
                 579*********999999885 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0     7e-05      0.14      10      57 ..      18      83 ..      11      94 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 7e-05
                   HHHHHHHHHHHTT-EEEEE-SSHHHHHHHHHTT...........EEE-SSHHHHHHHC.......S CS
  NAD_binding_2 10 MGsnmalnllkagykvavynrtkekveelvaeg...........akaaesieelvasl.......d 57
                   +G+ +a +l+++g kv+++ r++e++++lv++            ++ +++i+++++++       d
     EEA19131.1 18 IGEALAIKLVANGSKVVLVGRRQERLDSLVKQLgsdkssavqfdITKLQDISDFASKVtsehpdiD 83
                   79*****************************96688899999998899999999988766555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (272 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       458  (0.0255452); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.67u 0.33s 00:00:01.00 Elapsed: 00:00:00.58
# Mc/sec: 1415.95
//
Query:       EEA19132.1  [L=309]
Description: 4-nitrophenylphosphatase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.7e-29  100.5   0.0    8.7e-29   99.6   0.0    1.4  1  Hydrolase_6     Haloacid dehalogenase-like hydrolase
    8.9e-15   54.5   0.0    6.8e-14   51.7   0.0    2.1  2  Hydrolase_like  HAD-hyrolase-like
    7.4e-11   42.7   0.0    0.00017   21.9   0.0    3.1  3  Hydrolase       haloacid dehalogenase-like hydrolase
    0.00011   22.3   0.1      0.062   13.4   0.0    2.5  3  HAD_2           Haloacid dehalogenase-like hydrolase


Domain annotation for each model (and alignments):
>> Hydrolase_6  Haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.6   0.0   1.9e-32   8.7e-29       1      99 [.      26     128 ..      26     130 .. 0.95

  Alignments for each domain:
  == domain 1  score: 99.6 bits;  conditional E-value: 1.9e-32
                  EEEESTTTSEETTEE-TTHHHHHHHHHHTT-EEEEEE---SS-HHHHHHHHHHTT----GGGEEEHHHHHHHHHHHHSX....XXEEEEESXHHHHHH CS
  Hydrolase_6   1 flfDidGvLwrgdkaipgaaealnalraagkpvvllTNnsskseeeyakkleklgvditeeqvvtsataaaeylkkrka....dkkvlvigeeglree 94 
                  flfD+dGvLw gd+ + g ae+l+ lr++gk+vv++TNns+ks+ +y+kkl  lg++ + e++++s+++a+ y++++ +    ++kv+vige g+++e
   EEA19132.1  26 FLFDCDGVLWSGDHTFSGTAETLELLRSRGKRVVFVTNNSTKSRADYKKKLDGLGIPSNVEEIFSSSYSASIYISRILKlpanKRKVFVIGETGIEQE 123
                  89*************************************************************************98444555*************** PP

                  HHHTT CS
  Hydrolase_6  95 lkeag 99 
                  l++ +
   EEA19132.1 124 LRNEN 128
                  *9976 PP

>> Hydrolase_like  HAD-hyrolase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.0       0.2     9e+02      15      29 ..     103     117 ..      94     119 .. 0.78
   2 !   51.7   0.0   1.5e-17   6.8e-14       2      74 ..     229     302 ..     228     303 .. 0.95

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 0.2
                     HHH---GGGEEEEES CS
  Hydrolase_like  15 evlgsdpeevlmiGD 29 
                      +l +++++v++iG 
      EEA19132.1 103 LKLPANKRKVFVIGE 117
                     567899********6 PP

  == domain 2  score: 51.7 bits;  conditional E-value: 1.5e-17
                     .STTSSHHHHHHHHHH---GGGEEEEES-TTTHHHHHHHCT-EE.EEESSSSS-TTTHHHHHHHHT---SEEES CS
  Hydrolase_like   2 lgKPepemydfalevlgsdpeevlmiGDrlatDiagAnnaGwks.vLVltGvtrpedleepehkptyvaddlae 74 
                     lgKP++ m+d++  +++ d+++++m+GDr +tDi+++ + ++ + + VltGv +++d+   + +p +++d l +
      EEA19132.1 229 LGKPSQAMMDSIEGKFQFDRNRTCMVGDRTNTDIRFGIEGKLGGtLGVLTGVATKDDMLNGPVRPVAYVDKLSD 302
                     7****************************************986599**********99999********9986 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.1   0.2    0.0013       5.9       2      16 ..      24      38 ..      23      42 .. 0.87
   2 !   11.7   0.0   5.1e-05      0.23     119     197 ..      40     116 ..      36     133 .. 0.66
   3 !   21.9   0.0   3.8e-08   0.00017      69     206 ..     124     265 ..     104     268 .. 0.73

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0013
                SEEEEESBTTTBCHH CS
                xxxxxxxxxxxxxxx RF
   Hydrolase  2 ktvvfDkdGTLttge 16
                +t++fD+dG+L+ g 
  EEA19132.1 24 DTFLFDCDGVLWSGD 38
                79**********987 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 5.1e-05
                 BHTTHHHHHHHHHHTTEEEEEEESSEHHHHHHHHHHTT........GGGESEEEEHHCESSTTTSHHHHHHHHHHHTSTGGGEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase 119 vkpeaaeavasLkaagievvlltgdnpetaeraanqlG........ddyfdaviasdietvakpspegkvaaireLqgkpeevamVG 197
                  + ++ae+++ L+++g +vv +t+++ +      ++l+        +++f           +  s +++   i +L +++++v ++G
  EEA19132.1  40 TFSGTAETLELLRSRGKRVVFVTNNSTKSRADYKKKLDglgipsnvEEIF----------SSSYSASIYISRILKLPANKRKVFVIG 116
                 67899******************999988886666665333444443333..........333344444444444445555555554 PP

  == domain 3  score: 21.9 bits;  conditional E-value: 3.8e-08
                 HHHTHHHHHHHH..HCHHHHHHHHHHHHHHCHHHHHHTTHHHHHHHHH.HTHHBHTTHHHHHHHHHHTTEEEEEEESSEHHHHH..HHHHHTT..GGGE CS
                 xxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxx..xxxx RF
   Hydrolase  69 yaigkpewltal..dippdlgaaigsaqsqgrtvallqaralavftia.dplkvkpeaaeavasLkaagievvlltgdnpetae..raanqlG..ddyf 160
                 +   ++ ++      i  d    ++++ ++g t++l+   +++v+ +  d ++ + ++  a+++++ +g  ++l+t+ +++ ++  ++   +G    + 
  EEA19132.1 124 LRNENVPFIGGTdpAIRRDIVPGDYKLMADGDTSILD--PEVGVVLVGlDFHFNYLKMCLAFQYIR-RGA-IFLATNIDSTLPNqgSLFPGAGsiS-AP 217
                 5555555555555556666666667777888888888..555555554499999999999999999.888.9****98887777444444477633.33 PP

                 .SEEEEHHCESSTTTSHHHHHHHHHHHTSTGGGEEEEESSHH.HHHHH CS
                 .xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxx RF
   Hydrolase 161 .daviasdietvakpspegkvaaireLqgkpeevamVGDgvn.Daaal 206
                     +++d  + +kps+ ++  +  ++q + ++++mVGD+ n D+ ++
  EEA19132.1 218 lIMMLGKDPIALGKPSQAMMDSIEGKFQFDRNRTCMVGDRTNtDIRFG 265
                 35666666666*********************************9876 PP

>> HAD_2  Haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0      0.99   4.5e+03       2      10 ..      27      35 ..      26      40 .. 0.85
   2 !    6.3   0.0    0.0021       9.4      80     128 ..      40      91 ..      35     118 .. 0.80
   3 !   13.4   0.0   1.4e-05     0.062     126     166 ..     222     263 ..     214     268 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.99
       HAD_2  2 iFDlDgTll 10
                +FD Dg+l 
  EEA19132.1 27 LFDCDGVLW 35
                8*****996 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0021
       HAD_2  80 pydgvkelLeeLkeagyklgivTsk...sreaveekleqlgiesyFdvivts 128
                  ++g  e+Le L+++g ++  vT++   sr+  ++kl+ lgi s  + i +s
  EEA19132.1  40 TFSGTAETLELLRSRGKRVVFVTNNstkSRADYKKKLDGLGIPSNVEEIFSS 91 
                 6899*******************98433566677888888888777777665 PP

  == domain 3  score: 13.4 bits;  conditional E-value: 1.4e-05
       HAD_2 126 vtsedvekkKPdpeviekaleklklkkeeviyvGDsp.tDie 166
                 ++++ +   KP+++++  +  k++++++++ +vGD + tDi 
  EEA19132.1 222 LGKDPIALGKPSQAMMDSIEGKFQFDRNRTCMVGDRTnTDIR 263
                 677888899***************************999996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       366  (0.0204139); expected 358.6 (0.02)
Passed bias filter:                      360  (0.0200792); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.59u 0.32s 00:00:00.90 Elapsed: 00:00:00.52
# Mc/sec: 1782.01
//
Query:       EEA19133.1  [L=405]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00094   18.7   0.0     0.0016   17.9   0.0    1.3  1  RRG8      Required for respiratory growth protein 8 mitochond
  ------ inclusion threshold ------
       0.15   12.2   0.0       0.43   10.7   0.0    1.7  1  FeoC      FeoC like transcriptional regulator


Domain annotation for each model (and alignments):
>> RRG8  Required for respiratory growth protein 8 mitochondrial
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.0   1.8e-07    0.0016      61     106 ..     112     158 ..     104     170 .. 0.85

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 1.8e-07
        RRG8  61 dfeLknNlfaqLLasPmRsdkisklkvpkelLiqlKlrkt.eneadg 106
                 d  L+nN +a  LasP+R   ++ ++vpk +L ++ l++  +++ +g
  EEA19133.1 112 DARLRNNPWAVALASPIRNCTATSMRVPKAFLTEMGLVRQiDEAIEG 158
                 5679*******************************998873444445 PP

>> FeoC  FeoC like transcriptional regulator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   4.8e-05      0.43      28      51 ..     370     393 ..     358     399 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 4.8e-05
        FeoC  28 pealeamLeqwvrkGrvekvaata 51 
                 p+ ++amL++w+ kG v + a+ +
  EEA19133.1 370 PKSVDAMLAMWELKGYVMHDAEYV 393
                 7899*************9887755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (405 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       468  (0.026103); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.24s 00:00:00.74 Elapsed: 00:00:00.41
# Mc/sec: 2988.21
//
Query:       EEA19134.1  [L=257]
Description: ATP-dependent Clp protease, proteolytic subunit ClpP [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      8e-76  254.0   0.0    9.8e-76  253.7   0.0    1.0  1  CLP_protease  Clp protease
  ------ inclusion threshold ------
      0.095   12.9   1.1       0.18   12.0   1.1    1.4  1  Tugs          Tethering Ubl4a to BAGS domain


Domain annotation for each model (and alignments):
>> CLP_protease  Clp protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  253.7   0.0   1.1e-79   9.8e-76       5     181 ..      65     245 ..      61     246 .. 0.95

  Alignments for each domain:
  == domain 1  score: 253.7 bits;  conditional E-value: 1.1e-79
                   ECHHHHHHHHTTTEEEEES-BSHHHHHHHHHHHHHHHHH-SSS-EEEEEEE--B-HHHHHHHHHHHHHSSS-EEEEEEEEEETHHHHHHHTS-TTGE CS
  CLP_protease   5 raydiysrllkeriiflgseiddevankiiaqLllLeaedpdkdillyinspGGsvtaglaIydtmqyikpdvsticlGlaaSmgslllaagekgkR 101
                   ++ydi+srllkerii+l++e+d+++++ i+aqLl+Lea +p+k i+lyinspGGsvtaglaIydtm yi+++v+tic+G+aaSmgslll++g+ gkR
    EEA19134.1  65 HTYDIFSRLLKERIICLNGEVDETTSAAIVAQLLFLEADNPEKAIHLYINSPGGSVTAGLAIYDTMTYIQSPVHTICVGQAASMGSLLLCGGHAGKR 161
                   79*********************************************************************************************** PP

                   EEETTEEEEES-TEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH.HTS...-HHHHHHHHCSTEEEEHHHHHHHTSSSEE-SS CS
  CLP_protease 102 falpnarimihqPlggaqgqasdieieaeellkikerlneilakh.tgq...slekiekdldrdtflsaeeAveyGLideviek 181
                   ++lp++ imihqP+gg+ gqasdi+i+a+e+l+++++ln+i+++h tg+   sl++iek ++rd+f+ a+eA+e+G++de++++
    EEA19134.1 162 YCLPHSSIMIHQPSGGYFGQASDIAIHAKEILRVRTQLNQIYQRHlTGKkqlSLDEIEKLMERDYFMGAQEALEMGIVDEILDR 245
                   *******************************************9866662225799*************************986 PP

>> Tugs  Tethering Ubl4a to BAGS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   1.1   2.1e-05      0.18      19      44 ..     194     222 ..     189     224 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 2.1e-05
        Tugs  19 kVleqLrkeyersL...rrlsLddiErLA 44 
                 +V  qL + y+r L   ++lsLd+iE+L 
  EEA19134.1 194 RVRTQLNQIYQRHLtgkKQLSLDEIEKLM 222
                 7999**********7777*********96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (257 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       508  (0.028334); expected 358.6 (0.02)
Passed bias filter:                      480  (0.0267723); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 1789.26
//
Query:       EEA19135.1  [L=472]
Description: nucleolin protein Nsr1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    5.1e-41  138.3   0.0    4.5e-19   68.0   0.0    2.5  2  RRM_1        RNA recognition motif. (a.k.a. RRM, RBD, or RNP 
    0.00038   20.5   0.0       0.11   12.6   0.0    2.7  2  RRM_7        RNA recognition motif
     0.0066   16.4   0.0        1.5    8.9   0.0    2.5  2  Nup35_RRM_2  Nup53/35/40-type RNA recognition motif


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.0   0.0   7.6e-23   4.5e-19       1      69 [.     226     295 ..     226     296 .. 0.99
   2 !   68.0   0.0   7.6e-23   4.6e-19       1      70 []     332     402 ..     332     402 .. 0.99

  Alignments for each domain:
  == domain 1  score: 68.0 bits;  conditional E-value: 7.6e-23
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrel 69 
                 lf+gnL+++++ee L++ F+ fG+ + ++++++ etg+s+gf++Ve+++  +A++A ea   ++l+gr++
  EEA19135.1 226 LFIGNLSWNIDEEWLRREFESFGELSGVRIMTErETGRSRGFGYVEYADAASAKAAYEAKKDTELDGRTI 295
                 8*******************************************************************98 PP

  == domain 2  score: 68.0 bits;  conditional E-value: 7.6e-23
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrelk 70 
                 lf+gnL + v+e+ ++e+F+  G i+ i+l++d etg++kg+++VeF s ++A++Al+ l+g+ +ggr ++
  EEA19135.1 332 LFLGNLVFGVDENAVREVFESQGTIQGIRLPTDpETGRPKGYGYVEFSSVDEARQALNDLQGTDIGGRAIR 402
                 89******************************************************************996 PP

>> RRM_7  RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.0   1.8e-05      0.11       1      29 [.     223     251 ..     223     291 .. 0.81
   2 !    5.1   0.0    0.0041        25       1      58 [.     329     379 ..     329     404 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.8e-05
       RRM_7   1 srkvFvGGlPiDiteeelkatfkefgkvl 29 
                 s  +F+G l ++i+ee l + f++fg+++
  EEA19135.1 223 SSNLFIGNLSWNIDEEWLRREFESFGELS 251
                 6789**********************975 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0041
       RRM_7   1 srkvFvGGlPiDiteeelkatfkefgkvl.vdwPkkaeskkkaaenskaakgyvflvfe 58 
                 s  +F+G l   ++e+++ + f++ g+++ +  P  +e+ +         kgy ++ f+
  EEA19135.1 329 SNTLFLGNLVFGVDENAVREVFESQGTIQgIRLPTDPETGRP--------KGYGYVEFS 379
                 5678*********************99865777777666432........355555555 PP

>> Nup35_RRM_2  Nup53/35/40-type RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.0   0.0    0.0041        25      21      53 .]     244     282 ..     237     282 .. 0.81
   2 !    8.9   0.0   0.00025       1.5      15      53 .]     344     388 ..     340     388 .. 0.93

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0041
  Nup35_RRM_2  21 FasfGeIvkhyvp......kevsvmyvkfesekdaekAL 53 
                  F+sfGe     +       +++ + yv++++  +a+ A+
   EEA19135.1 244 FESFGELSGVRIMteretgRSRGFGYVEYADAASAKAAY 282
                  88899887744444577789999************9996 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.00025
  Nup35_RRM_2  15 elVlehFasfGeIvkhyvp......kevsvmyvkfesekdaekAL 53 
                  + V+e F+s G I  +  p      + + + yv+f s ++a +AL
   EEA19135.1 344 NAVREVFESQGTIQGIRLPtdpetgRPKGYGYVEFSSVDEARQAL 388
                  7899*******************996699***************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (472 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2492  (0.138993); expected 358.6 (0.02)
Passed bias filter:                      728  (0.0406046); expected 358.6 (0.02)
Passed Vit filter:                       435  (0.0242624); expected 17.9 (0.001)
Passed Fwd filter:                       200  (0.0111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 2.75u 0.42s 00:00:03.17 Elapsed: 00:00:00.70
# Mc/sec: 2032.36
//
Query:       EEA19136.1  [L=455]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
  ------ inclusion threshold ------
          5    7.7   6.3        3.3    8.2   0.4    2.9  3  Sperm_Ag_HE2  Sperm antigen HE2


Domain annotation for each model (and alignments):
>> Sperm_Ag_HE2  Sperm antigen HE2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0      0.57     1e+04      30      52 ..     128     150 ..     111     151 .. 0.61
   2 ?    1.4   0.2     0.025   4.4e+02      15      42 ..     209     236 ..     207     241 .. 0.84
   3 ?    8.2   0.4   0.00018       3.3      14      47 ..     314     347 ..     312     353 .. 0.93

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 0.57
  Sperm_Ag_HE2  30 egprelreespgqgtngsqllhh 52 
                   +  + ++e+  +q++  + ll+h
    EEA19136.1 128 KVMSGSNEDITAQSQGDALLLRH 150
                   33677788888888888888887 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.025
  Sperm_Ag_HE2  15 fpGsSrassvnhqategprelreespgq 42 
                    + sS+a+ + h++    r+ r  s  q
    EEA19136.1 209 VSNSSQATAIRHNSSSTVRNTRRSSRTQ 236
                   5679***********9999988877665 PP

  == domain 3  score: 8.2 bits;  conditional E-value: 0.00018
  Sperm_Ag_HE2  14 LfpGsSrassvnhqategprelreespgqgtngs 47 
                   ++pG  r+   n q++++pr+    +p +g+ ++
    EEA19136.1 314 MIPGTPRTDARNMQQPKPPRSISSSAPSKGKRKA 347
                   89****************************9765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (455 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       867  (0.0483574); expected 358.6 (0.02)
Passed bias filter:                      359  (0.0200234); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 3153.99
//
Query:       EEA19137.1  [L=482]
Description: MFS monocarboxylate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.5e-33  115.5  60.6    2.9e-25   88.9  29.4    2.1  2  MFS_1          Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.034   14.1   0.8       0.12   12.2   0.8    2.0  1  DUF3285        Protein of unknown function (DUF3285)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.9  29.4   3.3e-29   2.9e-25       4     294 ..      60     355 ..      51     357 .. 0.81
   2 !   40.6  23.3   1.6e-14   1.4e-10      22     150 ..     295     443 ..     292     477 .. 0.77

  Alignments for each domain:
  == domain 1  score: 88.9 bits;  conditional E-value: 3.3e-29
       MFS_1   4 aaflsalarsilgpalplalaed.....lgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqG 96 
                  +++ ++ ++ ++ al ++l+++      g+sp+ i l+ t+    + ++ +++  ++  f++r+v l+g+ +f  + ++++f++ lw + l   vl G
  EEA19137.1  60 FTCCGITFSFGIYQALYETLSHEpntpfTGASPALIDLIGTTAVGIMTIGGPLAVGWAKTFSPRKVCLMGAMIFTMAHIFASFGTKLWhFALTQGVLLG 158
                 344444444445555555666666666666***********************************8888888888884555599*************** PP

       MFS_1  97 lgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafv.lfllllpeepperkrkspkeee...kgt 191
                 lg+++++ ++++++  wf+  +rg+a+g++ +g+++G ++ +++  ++++++g+r +  + ++vs+++    +++  +e+ ++ +++ +++       +
  EEA19137.1 159 LGTCLAYMTSVTVAPTWFTT-RRGLAMGIILSGTGIGGLVWAPALKACVDAIGYRNTLRLTGAVSFVLNTgAGAAMTWEPSRKAQNEIERRAQamtTTH 256
                 *******************9.***********************************************4434445556555555555555555889999 PP

       MFS_1 192 gpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalg 290
                 +  plv+ w+++++++++     ++++ ++++++ ++++ +y  ++lg+s    ++ ++al+ + +ai+++++g+ +dr+gr + lll+ ++ +++al 
  EEA19137.1 257 FAVPLVD-WRLMKTRKFIA-QASGAVFQGAAYYIPVFFFATY-ASTLGYS-DTAGANFIALSNACNAIGKIVIGYAADRYGRLNVLLLTTIISAISALV 351
                 9999999.********663.4444444466777788888889.*******.356666688888888888************999999999988888888 PP

       MFS_1 291 lall 294
                 + + 
  EEA19137.1 352 FWVP 355
                 7765 PP

  == domain 2  score: 40.6 bits;  conditional E-value: 1.6e-14
       MFS_1  22 alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllf..a.........sslw.lllvlrvlqGlgagalfpagaa 108
                 ++a++lg+s ++    ++l  +  a++ +++G+ +dr+Gr  vlll+ +++a+++l++++  +         + +  l++++ ++ G++a+a++++  +
  EEA19137.1 295 TYASTLGYSDTAGANFIALSNACNAIGKIVIGYAADRYGRLNVLLLTTIISAISALVFWVpsTllpfashqeA-SRgLFIAFTIFYGVFASAYVALFPT 392
                 567889999999888899999999******************************7777733202333344422.6669********************* PP

       MFS_1 109 liadwfpkeergraigllsagfslGailgpllggllasslg..........W 150
                  ++++f +++ ++++g+l++  +l++++g +++gll+  ++          +
  EEA19137.1 393 SLVELFGPQNFASVNGFLYMLRGLATMVGTPVSGLLI-RGSttaavvtprmY 443
                 *************************************.44433555543332 PP

>> DUF3285  Protein of unknown function (DUF3285)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.8   1.4e-05      0.12      19      43 ..     143     167 ..     142     168 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 1.4e-05
     DUF3285  19 gkSLkHFfLTtvgllgllvglayLt 43 
                 g+ L+HF+LT   llgl   lay+t
  EEA19137.1 143 GTKLWHFALTQGVLLGLGTCLAYMT 167
                 5779*******************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (482 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       684  (0.0381505); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.32s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 3134.97
//
Query:       EEA19138.1  [L=517]
Description: sugar transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   4.4e-109  365.3  27.1   5.5e-109  365.0  27.1    1.0  1  Sugar_tr  Sugar (and other) transporter
    1.4e-26   93.3  24.2    1.4e-26   93.3  24.2    2.1  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.022   14.5   1.3      0.022   14.5   1.3    3.4  4  UNC-93    Ion channel regulatory protein UNC-93


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  365.0  27.1  9.1e-113  5.5e-109       5     452 .]      14     462 ..      11     462 .. 0.92

  Alignments for each domain:
  == domain 1  score: 365.0 bits;  conditional E-value: 9.1e-113
                 HHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHH.HHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS- CS
    Sugar_tr   5 aalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfag.llgdrfGRkkslliaavlfvigavlqaaakgknsv 102
                  ++ggl fgYdtg ++++l +++f++   + ++ s     + l+g+i+++ ++Ga++Gsl++g +l+d++GRkk+ll ++++f +g++++ +a+   +v
  EEA19138.1  14 PCTGGLAFGYDTGSMSGILVMPQFLT---YMNHPS-----NFLQGWITGSIQAGAFAGSLLTGaFLADKLGRKKTLLLGSAIFTVGIAISTVAN---NV 101
                 57899******************443...333333.....3568***************99884789***************************...** PP

                 TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHHT CS
    Sugar_tr 103 evlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPrylvek 201
                  vli gRv+ Gig G+  ++vP y+sEi+p ++Rg+++s++q +i fGil a+++ +g+++++++  wr+ +glq++p+ +l i ++flPESPr+lv++
  EEA19138.1 102 AVLISGRVINGIGNGCLAMMVPNYQSEISPREIRGRIISIQQCFINFGILAAFWIQYGTSHIDGEAAWRLAIGLQMIPTTILHITMYFLPESPRWLVQQ 200
                 *************************************************************************************************** PP

                 T-HHHHHHHHHHHHHC.....HHHHHHHHHHHHHHHHHHH......HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH...HH CS
    Sugar_tr 202 gkeeeakevlaklrge.....edadrelaeekdsleaeqeee.kaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsks...ll 291
                 ++++ea e la+l  +     + +  el e++++l+ e++   + + ++l++  +  +r+ +++++q++qq+tGin+imyy+  +f+++gl +    ll
  EEA19138.1 201 DRYQEALEALARLHSKgdvrdAYVRAELTEIITKLRWEKSHPpTSYASMLFGV-E-ARRTWLAIGVQFWQQVTGINVIMYYAVFLFQQAGLGEIyasLL 297
                 ************77666576677778888888888888555566666666666.4.79**********************************99999** PP

                 HHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS.........CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTH CS
    Sugar_tr 292 vtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgivalllvaks......kaasivaivfialfialfalgwgpvpwvlvsElfpqsvR 384
                 ++++ gv+  ++t+  ++ +d +GRR+ ++lG++gm i +++lg v + +++k         as++a++f++++++ fal+w++v wv+ sElf++++R
  EEA19138.1 298 ANGLGGVTLNIFTLLNMYYIDSWGRRRPMILGGIGMGISMMLLG-VIMRTKEKInfsfanRNASNAAVAFVYIYVMTFALTWACVAWVYPSELFSMNMR 395
                 *******************************************9.44444444489999999************************************* PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 385 skalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 + +++++ a+nw++nf   l +p+++++i+ ++ +l+f++l+ l++i+vf+f+pe +g++lee++ lf
  EEA19138.1 396 GRGTSFSSATNWFVNFWFVLYIPTAMNKIS-WKLYLIFMALCFLMAIVVFLFYPESAGKSLEEMDLLF 462
                 ******************************.*********************************9776 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.3  24.2   2.3e-30   1.4e-26      14     346 ..      29     407 ..      16     414 .. 0.80
   2 !    3.5   2.4    0.0045        27     148     178 ..     424     453 ..     412     471 .. 0.73

  Alignments for each domain:
  == domain 1  score: 93.3 bits;  conditional E-value: 2.3e-30
       MFS_1  14 ilgpalplalaedlgispseigllltlyalgaavaslpl.GrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgagalfpagaalia 111
                   ++++p++l+   + s   +g++++   +ga+++sl++ ++l+d++Gr+++lllg ++f +g+++ ++a+++ +l+ +rv+ G+g g+l+ ++  + +
  EEA19138.1  29 SGILVMPQFLTYMNHPSNFLQGWITGSIQAGAFAGSLLTgAFLADKLGRKKTLLLGSAIFTVGIAISTVANNVAVLISGRVINGIGNGCLAMMVPNYQS 127
                 445677779999999*****************99999997889********************55555657777************************* PP

       MFS_1 112 dwfpkeergraigllsagfslGailgpllggllasslg...Wravfyilaivsllafvlfllllpeepperkrkspkeee................... 188
                 +++p+e rgr i++ + ++++G++ +  +    ++  g   Wr++  +  i + ++ +     ++ ++++r+ + + +                     
  EEA19138.1 128 EISPREIRGRIISIQQCFINFGILAAFWIQYGTSHIDGeaaWRLAIGLQMIPTTILHI---TMYFLPESPRWLVQQDRYQealealarlhskgdvrday 223
                 *******************************99966669*****************99...7777777777777655555779********99999999 PP

       MFS_1 189 ...............kgtgpaplvp....awkallkdpvlwillialllfffgfsg..lltllplylqevlgls.glllaglllallalvgailallag 265
                                k++ p+   +    +++   ++     +l++ + f+  ++g  + ++  ++l ++ gl+   + ++l+ +l+++   i+ ll  
  EEA19138.1 224 vraelteiitklrweKSHPPT---SyasmLFGVEARRT----WLAIGVQFWQQVTGinVIMYYAVFLFQQAGLGeI-YASLLANGLGGVTLNIFTLLNM 314
                 888888777776333333333...33335555555555....55555555444444676666666789******42.555555777777777779999* PP

       MFS_1 266 rlsdrlgrrrrlllallllllaalglallavt...........ssavllllvlvliGfglgfv.fpsllalasdlappeeagtasglfntags 346
                 +++d +grrr+++l+++++ ++ ++l ++  t           + + +++++++++ ++++++  + ++++ s+l++ +++g+ +++ + ++ 
  EEA19138.1 315 YYIDSWGRRRPMILGGIGMGISMMLLGVIMRTkekinfsfanrNASNAAVAFVYIYVMTFALTwACVAWVYPSELFSMNMRGRGTSFSSATNW 407
                 ********************************99888888877555555556677777777774677889999999********999997665 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.0045
       MFS_1 148 lgWravfyilaivsllafvlfllllpeeppe 178
                 ++W  +++i+ ++++l++++++l++pe++ +
  EEA19138.1 424 ISWK-LYLIFMALCFLMAIVVFLFYPESAGK 453
                 5676.56777777777777777777766544 PP

>> UNC-93  Ion channel regulatory protein UNC-93
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   1.3   3.6e-06     0.022      39     138 ..      50     150 ..      41     160 .. 0.85
   2 ?   -0.9   0.8       0.2   1.2e+03      65      90 ..     263     288 ..     249     322 .. 0.69
   3 ?   -2.6   0.1      0.64   3.9e+03      36      60 ..     357     381 ..     334     390 .. 0.66
   4 ?   11.8   2.8   2.4e-05      0.15      41      87 ..     401     447 ..     393     450 .. 0.93

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 3.6e-06
      UNC-93  39 GYyslaiiyavftvanlvapsvvdlltakwalvigallyaifql.gFlllnkyylyissallGvgaallwtgqGsyLsenstretiernssilwallks 136
                 G+ + +i   +f+ + l+ + + d+l+ k +l++g++++++ ++ + +  n + l  + +++G+g   l +   +y se s re ++r  si+    ++
  EEA19138.1  50 GWITGSIQAGAFAGSLLTGAFLADKLGRKKTLLLGSAIFTVGIAiSTVANNVAVLISGRVINGIGNGCLAMMVPNYQSEISPREIRGRIISIQQCFINF 148
                 7777788889999999***********************9976515555666666667899*******************************9887777 PP

      UNC-93 137 sl 138
                  +
  EEA19138.1 149 GI 150
                 65 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.2
      UNC-93  65 takwalvigallyaifqlgFlllnky 90 
                 + ++ + ++++  ++++++Fl+    
  EEA19138.1 263 GVQFWQQVTGINVIMYYAVFLFQQAG 288
                 55666777788888999999987643 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 0.64
      UNC-93  36 kkaGYyslaiiyavftvanlvapsv 60 
                 ++a   ++a++y+  ++++l+ + v
  EEA19138.1 357 RNASNAAVAFVYIYVMTFALTWACV 381
                 4555566777777777777766655 PP

  == domain 4  score: 11.8 bits;  conditional E-value: 2.4e-05
      UNC-93  41 yslaiiyavftvanlvapsvvdlltakwalvigallyaifqlgFlll 87 
                 +s a+ ++v+  + l +p+ +++++ k+ l++ al++++ +++Fl+ 
  EEA19138.1 401 FSSATNWFVNFWFVLYIPTAMNKISWKLYLIFMALCFLMAIVVFLFY 447
                 578999**************************************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (517 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1041  (0.0580624); expected 358.6 (0.02)
Passed bias filter:                      492  (0.0274416); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.26s 00:00:00.91 Elapsed: 00:00:00.45
# Mc/sec: 3465.20
//
Query:       EEA19139.1  [L=299]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (299 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       454  (0.0253221); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.24s 00:00:00.68 Elapsed: 00:00:00.39
# Mc/sec: 2300.37
//
Query:       EEA19140.1  [L=605]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.8e-18   65.1  27.0    1.3e-17   63.6  27.0    1.6  1  Aa_trans  Transmembrane amino acid transporter protein


Domain annotation for each model (and alignments):
>> Aa_trans  Transmembrane amino acid transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.6  27.0   7.5e-22   1.3e-17      23     369 ..     149     509 ..     129     516 .. 0.86

  Alignments for each domain:
  == domain 1  score: 63.6 bits;  conditional E-value: 7.5e-22
    Aa_trans  23 aLPyAfkqlGlivGlillllvallslytlllLvkcsktla.sgkrnksYgdlgyrllGpkgkliidlailvqlfGvgvsyliligdllpaifesffdtl 120
                 +  +A+ +lG+ +G++ +++++++  y+ +l+ ++   ++  +   + Ygdl+ r+ G+ +++i+++++++ l+ ++   +i +g++++++ ++     
  EEA19140.1 149 GSGFAMGTLGWGPGIAFYTIFGFMAGYSGYLIYRVFLGVDsYEFPARNYGDLALRTWGRTLRYITNFCQALGLLLITGQVTIQFGENISQVSKF----- 242
                 45689********************************999878899***********************************************8..... PP

    Aa_trans 121 llsnvyfilisaliiipLslipnlskLsylSllalvsslyy..................ivilvlvvaelvklelkgvseetv.......kkasklkgl 194
                 +l+ ++  + ++++ +  ++i+ l+++++++  a+ + l++                  ++  + + ++ ++ ++ +++ +++        ++s   g 
  EEA19140.1 243 KLCYAVCPVLFVVAGFFITQIRTLRAYGWVANCAVWMNLLVifismgviansppnykisVLGSAGSAVDETTIKPDEYGVYPAiihynglPPNSL-VGS 340
                 5566666666666666778*****************999889999*********99987777778888888889999888888898888655555.666 PP

    Aa_trans 195 flaigiivFAftghavlleiqnelkdpskfkkmtkvlllsiilatvlyilvGlvGYltFGnevkgnillnlpkssilivivnlllvlhlilsfplqlhp 293
                 ++ +   v A++g  +++e+  e++ p++f    k++  +  +++++y++ G+++Y+  G        + ++ +s +++++n++ ++ ++++  l+   
  EEA19140.1 341 INGLLSGVLAYAGVQIFVEFLGEMRRPRDFI---KAMWGAQFFMYTVYLVYGCFVYYYQGQYSFNPSYQGVSIYS-WQTAGNMISLISALIAGGLYGNI 435
                 666666789********************99...9***********************99988888888888887.*********************** PP

    Aa_trans 294 lrqvvenllikkeavagasekeapkskllrlvirlllv.vityliAlsvpslakvlslvGatsstplsfilPalfhl 369
                  ++v+ n++     ++ + +  ++k++++ + + + l  +i+ +iA+ +p    ++s+++a     ++++lP+lf l
  EEA19140.1 436 GVKVFYNNILL---DFLDAPPINTKRGKFIYAMLVPLWwIIAFIIAAAIPDYFGFVSVISASILLNMTYTLPPLFAL 509
                 *****999965...47777777777777777666665505566789****************************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (605 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       663  (0.0369792); expected 358.6 (0.02)
Passed bias filter:                      359  (0.0200234); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.42
# Mc/sec: 4302.36
//
Query:       EEA19141.1  [L=385]
Description: acetyltransferase, GNAT family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      5e-05   24.0   0.0     0.0002   22.0   0.0    2.0  3  Acetyltransf_3   Acetyltransferase (GNAT) domain
    0.00023   21.4   0.1      0.001   19.3   0.1    2.0  1  Acetyltransf_1   Acetyltransferase (GNAT) family
    0.00087   19.2   0.1     0.0089   16.0   0.1    2.3  1  FR47             FR47-like protein
  ------ inclusion threshold ------
       0.03   14.7   0.0      0.062   13.7   0.0    1.5  1  Acetyltransf_7   Acetyltransferase (GNAT) domain
      0.067   13.3   0.0       0.17   12.0   0.0    1.6  1  Acetyltransf_CG  GCN5-related N-acetyl-transferase


Domain annotation for each model (and alignments):
>> Acetyltransf_3  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0       2.9     1e+04      93     133 ..     124     165 ..     119     166 .. 0.64
   2 ?   -2.0   0.0       1.5   5.5e+03     112     129 ..     274     291 ..     221     293 .. 0.73
   3 !   22.0   0.0   5.6e-08    0.0002      87     136 ..     310     367 ..     278     368 .. 0.86

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 2.9
  Acetyltransf_3  93 gkGyateavralleyafeelgler.lvavidkeNeaSirvle 133
                     ++ +a+e    ll+++ +el  e+     + ++ + S +vle
      EEA19141.1 124 RQDIAREQIWNLLKFIRRELMPEYiSHLSTGEKQQPSTAVLE 165
                     566888888888888888884443333455566666666665 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.5
  Acetyltransf_3 112 lglerlvavidkeNeaSi 129
                     l ++ +v+ +++ N+ S+
      EEA19141.1 274 LAMPSVVVYHHTGNTTSQ 291
                     367788999999998886 PP

  == domain 3  score: 22.0 bits;  conditional E-value: 5.6e-08
  Acetyltransf_3  87 lapsfwgkGyateavralleya........feelglerlvavidkeNeaSirvleklG 136
                     + p+++gkG+a    r +++           ++ +l +  a ++ +N aS+rv+ek+G
      EEA19141.1 310 VEPEHRGKGIAATLSREVMRRGmgggvygsSSKKELGYAHADVARDNVASRRVMEKVG 367
                     5689******************555554443444899*******************99 PP

>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.1   2.9e-07     0.001      63     116 ..     305     367 ..     283     367 .. 0.82

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 2.9e-07
                     EEEEEESGGGTTSSHHHHHHHHHHHHHHHT...TE...SEE.EE..EEETTEHHHHHHHHHTT CS
  Acetyltransf_1  63 ieslaVspeyrgkGlGsaLlealeeraree...gi...kki.vl..aveedndaairlYeklG 116
                     +  l+V pe+rgkG++ +L +++++r       g    k++ ++  +v  dn+a++r+ ek+G
      EEA19141.1 305 LATLHVEPEHRGKGIAATLSREVMRRGMGGgvyGSsskKELgYAhaDVARDNVASRRVMEKVG 367
                     6789*********************99999666443122344448899999999999999987 PP

>> FR47  FR47-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.1   2.5e-06    0.0089      13      49 ..     294     330 ..     284     378 .. 0.80

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 2.5e-06
                 EEEEEE-TTSSEEEEEE-GGG-SSSHHHHHHHHHHHH CS
        FR47  13 aawilrkdggelgalqvlpehrrrGlgsrlvkalake 49 
                 +aw +   +g+l  l v+pehr++G +  l +++ ++
  EEA19141.1 294 VAWGFLALDGSLATLHVEPEHRGKGIAATLSREVMRR 330
                 789899999*********************9999875 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   1.7e-05     0.062      16      48 ..     297     326 ..     274     357 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.7e-05
                     EEEEEEEESTCTEEEEE-GGGTTSSHHHHHHHH CS
  Acetyltransf_7  16 GfialslldaeitrlaVdpeyrgkGiGraLlea 48 
                     Gf+al     ++  l V pe+rgkGi+  L + 
      EEA19141.1 297 GFLALDG---SLATLHVEPEHRGKGIAATLSRE 326
                     5555444...466699***********999764 PP

>> Acetyltransf_CG  GCN5-related N-acetyl-transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   4.7e-05      0.17      31      51 ..     309     329 ..     303     331 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 4.7e-05
  Acetyltransf_CG  31 eVpeelrGkGiAkkLvkaald 51 
                       V++e+rGkGiA+ L ++++ 
       EEA19141.1 309 HVEPEHRGKGIAATLSREVMR 329
                      699**************9985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (385 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       355  (0.0198003); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.48u 0.24s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2822.42
//
Query:       EEA19142.1  [L=442]
Description: O-acetylhomoserine (thiol)-lyase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.1e-127  425.8   0.0   1.2e-127  425.6   0.0    1.0  1  Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
    9.1e-09   34.7   0.1    1.3e-08   34.3   0.1    1.3  1  Aminotran_5      Aminotransferase class-V
    7.6e-08   32.0   0.0    1.6e-07   30.9   0.0    1.4  1  Beta_elim_lyase  Beta-eliminating lyase
    6.1e-06   25.8   1.0    1.3e-05   24.7   1.0    1.5  1  DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family
     0.0022   16.9   0.0     0.0031   16.4   0.0    1.1  1  GDC-P            Glycine cleavage system P-protein
  ------ inclusion threshold ------
      0.075   11.5   0.1       0.17   10.4   0.1    1.6  1  Met_gamma_lyase  Methionine gamma-lyase
       0.26   10.9   1.3       0.48   10.1   0.2    2.1  2  BRK              BRK domain


Domain annotation for each model (and alignments):
>> Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  425.6   0.0  4.7e-131  1.2e-127       1     381 [.      14     432 ..      14     433 .. 0.97

  Alignments for each domain:
  == domain 1  score: 425.6 bits;  conditional E-value: 4.7e-131
                      HHHHHHTTTTCHTTTTBSS--B---SBBBESSHHHH....CTTCSSS-SBTTT--HHHHHHHHHHHHHHT-SEEEEESSHHHHHHHHHHTTS-T CS
  Cys_Met_Meta_PP   1 eTllvhagqekdeqtgavavpiyltstykfkdvdea....fageekgyeYsRsgnptrsvleeriaaLeggeaalavssGmaAiaaailallka 90 
                      eTl++h+g+ +d q+ga +vp+y ++++ f d+++a     +  +++y+YsR+ npt++v+e+riaaLegg+aa+a+ssG aA+ +a+l+l++a
       EEA19142.1  14 ETLQLHTGNFRD-QFGACSVPVYSSASFWFPDSKTAgnsmVNFTADAYVYSRTSNPTVHVFEQRIAALEGGTAAVAFSSGAAAVLVAVLSLARA 106
                      699*******99.8*****************9999888866666777*********************************************** PP

                      TEEEEEESTSSHHHHHHHHHTHHHTTCEEEEE.STTSHHHHHHHCCTTEEEEEEESS-TTTT----HHHHHHHHHHTT-EEEEEGTTTHT.TTS CS
  Cys_Met_Meta_PP  91 GdeivvsddlYggtqrllkkvlkklgievkfv.dtsdleelekaikentklvylEtptnpllkvvDiekiaklakkagvlvvvDntfasp.llq 182
                      G++i+++++++ggt+++++++l+ lgie++fv d +++ee+++ i+ent+l+++Et++np   v+D+  ++++a+++g+++vvD+tf++  +++
       EEA19142.1 107 GSNIISTRSIHGGTYHQFHTLLSGLGIEARFVrDEASIEEIRQLIDENTRLIFTETIGNPSFTVADFDVLSEAAHQNGIPLVVDATFSAAgYFC 200
                      *******************************967799**************************************************8655*** PP

                      -GGGGT-SEEEEETTTTTTCSSS--EEEEEESSCHHHHHHHHHHH................................HHHT-B--HHHHHHHHH CS
  Cys_Met_Meta_PP 183 rplklgaDivvhSaTKylgGhsdvvaGvivvkgkeelkkelkflq................................nalGavlspfdawlllr 244
                      rp+++gaDiv+hSaTK++gGh+++++Gviv++gk++++ + ++++                                +++G++ls ++a  ll 
       EEA19142.1 201 RPIDHGADIVIHSATKWIGGHGTTLGGVIVDSGKFDWGANPEKFPqfhggregtadlnlykvfgteayaamlkadtlRDIGSTLSSQAAHELLI 294
                      ***************************************9999888************************************************ PP

                      HHTTHHHHHHHHHHHHHHHHHHHHTSTTEEEEE-TTSTTSTTHHHHHHHSS.SG-SEEEEEESSHHHHHHHHHHC-SSSEECSS-SSSS-EEEE CS
  Cys_Met_Meta_PP 245 GlkTLslRlerhqenAlkvAefLekhpkvekvyYpglpshpqhelakkqlk.gaggvlsFelkseeekakkfvdnlklfslaeslGgvesliel 337
                      Gl+TLslR er+++nA+++Ae+Lekhp v++v+Y gl++hp+h+la k+l+ g+g+vl+F +k+++++  k+ dnl+l+ +++++G+ +++i++
       EEA19142.1 295 GLETLSLRAERQASNAMQLAEWLEKHPLVSWVQYLGLENHPSHQLALKYLSrGFGSVLAFGVKGGQNAGLKLADNLELIGHTANVGDSKTIIIH 388
                      ************************************************98625677************************************** PP

                      TTTTTTTTSCHHHHHHTTS-TTEEEEE--SS-HHHHHHHHHHHH CS
  Cys_Met_Meta_PP 338 pasmthasipkeereaagvtddliRlsvGiEdvdDliaDlkqal 381
                        s+th ++++ee  a gvtddliRls G E++dDl++Dl+qal
       EEA19142.1 389 HRSTTHSQLTEEECLAIGVTDDLIRLSAGTEHIDDLKEDLDQAL 432
                      *******************************************9 PP

>> Aminotran_5  Aminotransferase class-V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.3   0.1   4.9e-12   1.3e-08      49     210 ..      74     225 ..      50     320 .. 0.86

  Alignments for each domain:
  == domain 1  score: 34.3 bits;  conditional E-value: 4.9e-12
                  HHHHHHHHT-STGGGEEEESSHHHHHHHHHHHCCCC-TTTSEEEEETTSHGGGTHHHHHHHHHHTEEEEEEEBETTSCBEGGGHHHH--TTEEEEEEE CS
  Aminotran_5  49 rekvaelinaeseeeiiftsGtteainlvalslarslkpgdeivvteaehhanlvpwqelakrtgakvkvipldeegeldldelekllnektklvait 146
                  ++++a+l + +    + f sG++ a+ +++lsl    ++g +i+ t++ h ++    + l    g++ ++  + +  e  ++e+++l++e+t+l++  
   EEA19142.1  74 EQRIAALEGGTA--AVAFSSGAA-AVLVAVLSL---ARAGSNIISTRSIHGGTYHQFHTLLSGLGIEARF--VRD--EASIEEIRQLIDENTRLIFTE 161
                  566666666664..777888877.777777888...78****************8888887555555555..544..55667**************** PP

                  SBETTTTEB--HHHHHHHHHHTT-EEEEE-TTTTTTS---HHHHTESEEEEETTTTTSSTT-EE CS
  Aminotran_5 147 hvsnvtGtiqpveeigklakkkgalvlvDaaqavghipidvkklgvDflafsghKllgPtGiGv 210
                   + n + t+ +++ + ++a+++g+ ++vDa+ ++  +     + g+D++  s+ K +g  G+++
   EEA19142.1 162 TIGNPSFTVADFDVLSEAAHQNGIPLVVDATFSAAGYFCRPIDHGADIVIHSATKWIGGHGTTL 225
                  *************************************************************974 PP

>> Beta_elim_lyase  Beta-eliminating lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.9   0.0   6.1e-11   1.6e-07      30     276 ..      66     323 ..      46     328 .. 0.73

  Alignments for each domain:
  == domain 1  score: 30.9 bits;  conditional E-value: 6.1e-11
                      --HHHHHHHHHHHHHTT-SEEEEES-HHHHHHHHHHHH--TTEEEEEETT-HHHHSST.THHHHCC--EEEEE-EBTTTBE-HHHHHHHS--S- CS
  Beta_elim_lyase  30 edktvnrLedavaelfgkeaalfvpqGtaAnsillkillqrgeevivtepahihfdet.gaiaelagvklrdlknkeaGkmdlekleaaikevg 122
                       ++tv+++e+++a+l g  aa+ + +G aA  +++  l++ g+++i t+  h+ ++ +   +    g+++r ++ ++    ++e+++++i+e  
       EEA19142.1  66 SNPTVHVFEQRIAALEGGTAAVAFSSGAAAVLVAVLSLARAGSNIISTRSIHGGTYHQfHTLLSGLGIEARFVRDEA----SIEEIRQLIDE-- 153
                      589***********************************************999999873333333555555555555....***********.. PP

                      TTS-EEEEEEEESSBTTTTTB---HHHHHHHHHHHHHCT-EEEEEETTHHHHHHHHTS-CHHHHTTSSEEEEESSS...TT--SS-EEEEE-HH CS
  Beta_elim_lyase 123 aheekiklisltvTnntagGqvvsleelrevaaiakkygiplhlDgARfanaakslgeivkemfsyvDsvtmslkK...dllanvGgvlafrdd 213
                          +++li +++  n       +++  + +++ a+++gipl++D++  + aa   g   + +  ++D+v  s++K   + ++  Ggv++ + +
       EEA19142.1 154 ----NTRLIFTETIGN----PSFTVADFDVLSEAAHQNGIPLVVDAT--FSAA---GYFCRPIDHGADIVIHSATKwigGHGTTLGGVIVDSGK 234
                      ....799999887666....5899**********************7..6666...77788888999999999999775567788999988888 PP

                      ....HHHHHHHHHHHHT---SSTHHHHH..............................HHHHHHHHSSTTHHHHHHHHHHHHHHHHHCT-- CS
  Beta_elim_lyase 214 eledylaerveqrkylggglrqagvlaa............................leagiraleeglaslerdhktaeqlaeklelvrla 276
                        +d  a+  ++ + +gg+   a++                                +  ++ le  + ++er+  +a qlae le+++l+
       EEA19142.1 235 --FDWGANPEKFPQFHGGREGTADLNLYkvfgteayaamlkadtlrdigstlssqaAHELLIGLETLSLRAERQASNAMQLAEWLEKHPLV 323
                      ..44444444444444444444443333344444444444444444444444444444556666777777778888888888777777765 PP

>> DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   1.0   5.2e-09   1.3e-05      20     146 ..      65     192 ..      48     214 .. 0.81

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 5.2e-09
                      SSSHHHHHHHHHHHHHHT-SEEEEESSHHHHHHHHHHHTTTTTT-EEEEESSS-THHHH....HHHHTT-EEEEE-B-TTTSSB-GGGCGGG-- CS
  DegT_DnrJ_EryC1  20 tsgpeveeFEkafaaylgvkhaiavssGtaAlhlaLralgvgpgdeVIvpsltFvatan....avlelgakpvfvDvdpdtynidpaaieaait 109
                      ts+p+v+ FE+++aa  g   a+a+ssG aA+++a   l    g  +I +     +t +      + lg ++ fv  +      + ++i+++i 
       EEA19142.1  65 TSNPTVHVFEQRIAALEGGTAAVAFSSGAAAVLVAVLSLARA-GSNIISTRSIHGGTYHqfhtLLSGLGIEARFVRDE-----ASIEEIRQLID 152
                      459*******************************99998766.9****998755555541111677888888888544.....6789******* PP

                      TTEEEEEEB-GGGB....---HHHHHHHHHHCT-EEEEE-T CS
  DegT_DnrJ_EryC1 110 ertkaIlpVhlyGq....vadmdalkaiaakhglkvieDaA 146
                      e+t+ I++ ++ G+    vad+d l + a++ g++++ Da 
       EEA19142.1 153 ENTRLIFT-ETIGNpsftVADFDVLSEAAHQNGIPLVVDAT 192
                      ****9986.66666222257*******************96 PP

>> GDC-P  Glycine cleavage system P-protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0   1.2e-06    0.0031     140     259 ..      93     216 ..      77     227 .. 0.71

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 1.2e-06
                 HHHHHHHHHH-SSS--EEEEETTS-HHHHHHHHHHHGGGT-EEEEE-..GGG--S-....S-EEEEEEEE.S-TTSB----HHHHHHHHHTT-EEEEEE CS
       GDC-P 140 aEAvllaaraskkkakkvvvdkkvhpqtlevlktrakglgieivevd..lteekvtd.kekevagvlvqy.pnteGriedlkelvekakkkkslvvvaa 234
                 a Avl+a+    +  ++++  +++h  t +  +t  +glgie   v    + e++ +   +++  ++     n + ++ d++ l+e+a+++ + +vv a
  EEA19142.1  93 AAAVLVAVLSLARAGSNIISTRSIHGGTYHQFHTLLSGLGIEARFVRdeASIEEIRQlIDENTRLIFTETiGNPSFTVADFDVLSEAAHQNGIPLVVDA 191
                 33444444444555677888899*****************99754440033333433433344333333213445579********************* PP

                 -TTGGGTB--HHHHT-SEEEEE-TT CS
       GDC-P 235 dllaLtllkpPgelgaDivvGsaqr 259
                    a + +  P + gaDiv+ sa +
  EEA19142.1 192 TFSAAGYFCRPIDHGADIVIHSATK 216
                 ********************98865 PP

>> Met_gamma_lyase  Methionine gamma-lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.1   6.6e-05      0.17     141     239 ..     140     232 ..      59     263 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 6.6e-05
  Met_gamma_lyase 141 gkvdieavkeaikektkliliqrskGyserkslsieeieeiiklvkeinedvivfvdncyGefveekePtevGadliaGsliknpGGgiaktGG 234
                      ++  ie++++ i e+t+li    + G    +s+++++ + + ++ +  ++ + + vd  +        P++ Gad++  s  k +GG  ++ GG
       EEA19142.1 140 DEASIEEIRQLIDENTRLIFTE-TIG---NPSFTVADFDVLSEAAH--QNGIPLVVDATFSAAGYFCRPIDHGADIVIHSATKWIGGHGTTLGG 227
                      4567888999999999999765.344...69999999986666544..45566779999999889999************************** PP

  Met_gamma_lyase 235 yiaGk 239
                       i+  
       EEA19142.1 228 VIVDS 232
                      *9843 PP

>> BRK  BRK domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.2   0.00019      0.48      26      38 ..     310     322 ..     305     327 .. 0.84
   2 ?   -3.1   0.1       2.4   6.2e+03      33      41 ..     331     339 ..     331     340 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00019
         BRK  26 lkdLeeWLeenPg 38 
                 +++L+eWLe++P 
  EEA19142.1 310 AMQLAEWLEKHPL 322
                 789*********5 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 2.4
         BRK  33 LeenPgyev 41 
                 Le +P +++
  EEA19142.1 331 LENHPSHQL 339
                 899**9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (442 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       500  (0.0278878); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.60u 0.32s 00:00:00.92 Elapsed: 00:00:00.49
# Mc/sec: 2714.38
//
Query:       EEA19143.1  [L=1689]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.5e-07   31.6   0.3    5.6e-06   26.5   0.0    2.9  3  rve              Integrase core domain
    4.8e-07   29.7   0.0    9.2e-07   28.7   0.0    1.3  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    0.00022   21.0   0.2    0.00073   19.3   0.2    1.8  1  gag_pre-integrs  GAG-pre-integrase domain
  ------ inclusion threshold ------
      0.032   14.3   1.4       0.46   10.6   0.1    2.8  2  Integrase_H2C2   Integrase zinc binding domain
       0.14   12.4   0.0       0.74   10.0   0.0    2.3  2  PAC4             Proteasome assembly chaperone 4


Domain annotation for each model (and alignments):
>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0       2.3   8.4e+03      71      98 ..     499     530 ..     495     533 .. 0.80
   2 ?    1.5   0.0     0.092   3.3e+02      30      91 ..     758     825 ..     754     830 .. 0.76
   3 !   26.5   0.0   1.6e-09   5.6e-06       7     117 ..     847     950 ..     842     952 .. 0.78

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 2.3
         rve  71 lsDngseytsk....afrefladlgirvsftr 98 
                 ++D  ++ +      a+ +f++++  ++++ r
  EEA19143.1 499 HTDEERTAARArykpAWDKFIQQYEGTPDMER 530
                 6777776664478899********99998877 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.092
         rve  30 vddfsrlilaealsdemdastvlalleravarfggve.......pervlsDngseytskafrefladlg 91 
                 + d+s + ++ +  de++  +++  l+r  +rfg+          +r  +D  +e++ +++ +f+++ +
  EEA19143.1 758 IWDYSLMSYITQSFDEDQCFLTATELRRLHRRFGHPSvgrlhktLLRAGYDTNPEMI-EKINRFCHHCQ 825
                 679999**********55555555555555566655599999888889999999999.88888888865 PP

  == domain 3  score: 26.5 bits;  conditional E-value: 1.6e-09
         rve   7 lwqvDvtvvripdgggkayllvvvddfsrlilaealsdem..dastvlalleravarfggvepervlsDngseytskafrefladlgirvsftrpgrpq 103
                  + vD+++++    g  + +l++vd ++r+  a+ l + +  ++ ++l++l+  ++ + g  p+ +++D g+ ++sk+f+ ++++lg+     ++   +
  EEA19143.1 847 SIIVDIMYIN----G--KPVLHIVDEATRFNAACWLISISarATWDALRMLW--IDTYLGP-PDFIVTDAGKNFVSKEFTHLASSLGTITVSVPVEAHW 936
                 5667888888....3..5688999**99997666555552004444444444..6666666.**************************999999999** PP

         rve 104 dnGkvErfhrtlkd 117
                 + G vEr h  l++
  EEA19143.1 937 SIGAVERYHAVLRR 950
                 *********99987 PP

>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.7   0.0   2.6e-10   9.2e-07       7     122 ..    1209    1326 ..    1205    1336 .. 0.82

  Alignments for each domain:
  == domain 1  score: 28.7 bits;  conditional E-value: 2.6e-10
       RVT_2    7 slPkdrkaigsrWvftkkkddlkevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeee.lvvhqldvdsafLnae..ldeevyvkqP 100 
                  + P + +  g r+v   k++  +++  k+rlv+q ++ k ++++  + +P i+ +s rL+l + + ++ +  +  dv  a+++++  l+ e y++ P
  EEA19143.1 1209 DIPLEARIYGFRFVDEVKNKGTDKAFEKSRLVVQAYNDK-DKEFVLTQSPTIQRSSQRLILCIGTSKDgVRFWIRDVTQAYIQSTtkLNREFYIRIP 1304
                  568889999*********9999**************987.567999*****************876651556677*******987336778****** PP

       RVT_2  101 pGfeidreeekvykLnkslyGl 122 
                  p         +  ++ + lyG+
  EEA19143.1 1305 PELRHYFPGCEFLRVVRPLYGI 1326
                  *988776666777777777774 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.2     2e-07   0.00073      22      63 ..     781     825 ..     765     826 .. 0.76

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 2e-07
  gag_pre-integrs  22 ssinlWHrRLGHpsfsrlkkLfkkgllpglki..sk.sevCeaCq 63 
                      +++++ HrR+GHps++rl+k   +   + +++  +k +++C++Cq
       EEA19143.1 781 TELRRLHRRFGHPSVGRLHKTLLRAGYDTNPEmiEKiNRFCHHCQ 825
                      678899************9988544444444333555889****9 PP

>> Integrase_H2C2  Integrase zinc binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.1       0.1   3.6e+02      25      42 ..     294     311 ..     292     313 .. 0.86
   2 ?   10.6   0.1   0.00013      0.46      10      53 ..     783     828 ..     778     831 .. 0.89

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.1
  Integrase_H2C2  25 tlerlrrryyWpgmrkdv 42 
                     +l+ ++  yyW ++++ +
      EEA19143.1 294 MLKDVALSYYWDNIDQWI 311
                     7889999*******9977 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00013
  Integrase_H2C2  10 lkeaHdsagHlGiektlerlrrryy..WpgmrkdvkkyvksCetCq 53 
                     l+++H   gH+++ +  ++l r  y   p m +++++++++C+t  
      EEA19143.1 783 LRRLHRRFGHPSVGRLHKTLLRAGYdtNPEMIEKINRFCHHCQTYG 828
                     899****************99999866799************9875 PP

>> PAC4  Proteasome assembly chaperone 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0       4.6   1.7e+04      27      42 ..     365     380 ..     347     392 .. 0.66
   2 ?   10.0   0.0   0.00021      0.74      32      70 ..     544     584 ..     521     587 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 4.6
        PAC4  27 plgslvvAmpsrtnkk 42 
                 +l++l +++p+  + +
  EEA19143.1 365 KLQDLFYCLPDELQTQ 380
                 5799999999988733 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00021
        PAC4  32 vvAmpsrtnkktptisTtLlgdg.sde..aserlAqrLArRl 70 
                  +++p+rt+ + pt++T  ++   +d   +s++lA+ LA R 
  EEA19143.1 544 QYSLPDRTK-NEPTTATGYFTVAaTDHneFSSSLASELANRS 584
                 69******9.7799999999777553355**********995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1689 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       662  (0.0369234); expected 358.6 (0.02)
Passed bias filter:                      516  (0.0287802); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 1.03u 0.28s 00:00:01.31 Elapsed: 00:00:00.52
# Mc/sec: 9746.93
//
Query:       EEA19144.1  [L=664]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
  ------ inclusion threshold ------
      0.033   13.2   0.2      0.049   12.7   0.2    1.3  1  Fungal_trans  Fungal specific transcription factor domain
       0.19   10.9   0.0       0.37   10.0   0.0    1.4  1  DUF4185       Domain of unknown function (DUF4185)


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.2   5.5e-06     0.049     125     207 ..     301     376 ..     264     492 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 5.5e-06
  Fungal_trans 125 rslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrpp.llddsqinlpLPcddddlwesddaseetlvetk 207
                   + +gLh  ps+        ++++ ae+r+R+      +Dk +++ +Grpp l +    + +LP d  d+   ++++  ++  + 
    EEA19144.1 301 YAMGLHHQPSDH-------VPFFLAETRKRMLAVSHRTDKNLSTAMGRPPrL-PHRYCDEALPLDLPDESLFEEKDSLERFLQR 376
                   679999998886.......67888**************************64.6666665655555544444444444443333 PP

>> DUF4185  Domain of unknown function (DUF4185)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   4.1e-05      0.37      88     133 ..     134     179 ..     105     208 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 4.1e-05
     DUF4185  88 kgvevtviPtagisvggtqylsymsvrswgapgewttnysaiaksd 133
                 ++  +tviP+ ++    +q +  m  + w+ +g+w + ys ++ ++
  EEA19144.1 134 DKGRFTVIPAPIVLDSLSQTVAHMESHPWNVTGNWASIYSDLMAAT 179
                 45679***********************************999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (664 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       573  (0.0319594); expected 358.6 (0.02)
Passed bias filter:                      502  (0.0279993); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.46
# Mc/sec: 4380.69
//
Query:       EEA19145.1  [L=638]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
  ------ inclusion threshold ------
      0.031   13.3   0.2      0.046   12.8   0.2    1.3  1  Fungal_trans  Fungal specific transcription factor domain
       0.18   11.0   0.0       0.35   10.1   0.0    1.4  1  DUF4185       Domain of unknown function (DUF4185)


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.2   5.1e-06     0.046     125     229 ..     301     401 ..     264     495 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 5.1e-06
  Fungal_trans 125 rslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrpp.llddsqinlpLPcddddlwesddaseetlvetk...lsneeksrki 217
                   + +gLh  ps+        ++++ ae+r+R+      +Dk +++ +Grpp l +    + +LP d  d+   ++++  ++  +       ++ ++  
    EEA19145.1 301 YAMGLHHQPSDH-------VPFFLAETRKRMLAVSHRTDKNLSTAMGRPPrL-PHRYCDEALPLDLPDESLFEEKDSLERFLQRlddGGWNRDGKFY 389
                   679999998886.......67888**************************64.66666655555555444444444444433332222333333334 PP

  Fungal_trans 218 asfllaLkkils 229
                   +  l ++ +ils
    EEA19145.1 390 PATLMRMRHILS 401
                   444444444444 PP

>> DUF4185  Domain of unknown function (DUF4185)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   3.9e-05      0.35      88     133 ..     134     179 ..     105     208 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 3.9e-05
     DUF4185  88 kgvevtviPtagisvggtqylsymsvrswgapgewttnysaiaksd 133
                 ++  +tviP+ ++    +q +  m  + w+ +g+w + ys ++ ++
  EEA19145.1 134 DKGRFTVIPAPIVLDSLSQTVAHMESHPWNVTGNWASIYSDLMAAT 179
                 45679***********************************999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (638 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       529  (0.0295053); expected 358.6 (0.02)
Passed bias filter:                      454  (0.0253221); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.30s 00:00:00.94 Elapsed: 00:00:00.50
# Mc/sec: 3822.50
//
Query:       EEA19146.1  [L=1348]
Description: oligomycin resistance ATP-dependent permease yor1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.3e-50  169.2   0.3    3.4e-27   95.6   0.0    3.1  3  ABC_tran       ABC transporter
    7.5e-44  150.4  40.9    1.5e-25   90.4  15.8    3.2  3  ABC_membrane   ABC transporter transmembrane region
    3.4e-06   27.5   1.0      0.014   15.7   0.1    3.1  2  AAA_16         AAA ATPase domain
    6.7e-06   26.2   4.7       0.03   14.4   0.1    3.3  3  MMR_HSR1       50S ribosome-binding GTPase
    2.6e-05   24.2   7.0       0.21   11.4   0.5    4.3  4  AAA_21         AAA domain, putative AbiEii toxin, Type IV TA 
    2.8e-05   23.5   0.1      0.011   15.0   0.0    3.1  3  Zeta_toxin     Zeta toxin
    0.00025   21.6   1.0       0.59   10.6   0.0    2.6  2  AAA_23         AAA domain
    0.00058   19.8   2.7       0.57   10.1   0.3    2.5  2  RsgA_GTPase    RsgA GTPase
    0.00065   19.2   8.3       0.51    9.7   0.4    4.3  3  SMC_N          RecF/RecN/SMC N terminal domain
      0.001   18.8   2.1       0.56   10.0   0.1    2.6  2  AAA_29         P-loop containing region of AAA domain
     0.0014   18.4   3.4       0.13   12.0   0.5    3.1  3  AAA_30         AAA domain
     0.0025   16.8   2.0       0.46    9.4   0.1    2.3  2  MeaB           Methylmalonyl Co-A mutase-associated GTPase Me
     0.0028   17.3   0.3       0.96    9.1   0.0    2.3  2  ATP-synt_ab    ATP synthase alpha/beta family, nucleotide-bin
     0.0058   16.2   0.9       0.12   11.9   0.1    2.4  2  cobW           CobW/HypB/UreG, nucleotide-binding domain
     0.0068   16.6   0.3        4.8    7.4   0.0    2.9  2  Roc            Ras of Complex, Roc, domain of DAPkinase
  ------ inclusion threshold ------
       0.04   13.3   0.7        7.5    5.8   0.0    2.2  2  FtsK_SpoIIIE   FtsK/SpoIIIE family
      0.047   12.6   3.8        0.3   10.0   0.3    2.2  2  TrwB_AAD_bind  Type IV secretion-system coupling protein DNA-
      0.067   13.5   3.5         12    6.2   0.4    3.2  2  AAA_22         AAA domain
      0.071   12.2   1.8       0.49    9.4   0.1    2.3  2  T2SSE          Type II/IV secretion system protein
      0.083   12.4   1.4        8.4    5.9   0.0    2.5  2  AAA_7          P-loop containing dynein motor region
       0.09   12.5   0.4        8.5    6.1   0.0    3.2  3  DEAD           DEAD/DEAH box helicase
       0.11   12.4   1.5       0.58   10.0   0.2    2.3  2  NACHT          NACHT domain
       0.11   12.3   1.8       0.96    9.4   0.2    2.3  2  MobB           Molybdopterin guanine dinucleotide synthesis p
       0.13   12.4   6.4       0.69   10.0   0.3    2.5  2  DUF87          Helicase HerA, central domain
       0.15   11.7   0.5         16    5.0   0.1    2.4  2  AAA_15         AAA ATPase domain
        0.2   11.2   0.3          3    7.4   0.0    2.5  2  AAA_25         AAA domain
        0.3   10.2   4.5        2.9    7.0   0.5    2.6  2  NB-ARC         NB-ARC domain
       0.52   10.4  10.6       0.29   11.2   0.8    2.8  2  Dynamin_N      Dynamin family
       0.64   10.1   5.6        2.9    7.9   0.6    2.8  2  PgaD           PgaD-like protein


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.1         8     5e+03      24      46 ..     188     210 ..     169     255 .. 0.61
   2 !   70.4   0.0   3.4e-22   2.1e-19       1     136 [.     501     635 ..     501     636 .. 0.87
   3 !   95.6   0.0   5.5e-30   3.4e-27       1     136 [.    1100    1264 ..    1100    1265 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 8
                 HHHHHHHHTTSS--SEEEEEETT CS
                 xxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  24 KStLlkllagllkpteGeilldg 46 
                  S L++++  ++ + + + +++g
  EEA19146.1 188 RSVLISAIFTKSMKLSNRAKIQG 210
                 35555555555555555555554 PP

  == domain 2  score: 70.4 bits;  conditional E-value: 3.4e-22
                 EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH............HHHTCHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............xxxxxxxx RF
    ABC_tran   1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren............esdeeiek 87 
                 lk ++++  +ge+vaivG  G+GK++Ll+++ g++++t+G+i             +l  + +++pq++ +++++ +r+n            ++ +e+ +
  EEA19146.1 501 LKSITMTAGRGELVAIVGAVGSGKTSLLSAIVGEMRKTSGQI-------------ILGGSKAYCPQHAWIQNTT-IRDNiifgkpfdpewyQRVVEACA 585
                 68999*************************************.............8999********8888877.*********988875444444555 PP

                 HHHHSTTGG.TTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 xxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  88 alsklglke.lkdtvvksspssLSgGqkqrvalarallkkpkllllDEpt 136
                 +++ +++    + t +++++ +LSgGqkqr+ lara+  +++++l+D+p 
  EEA19146.1 586 LVADFKILPaGDMTEIGERGINLSGGQKQRINLARAIYFQSDIILMDDPL 635
                 55555544345678889999****************************97 PP

  == domain 3  score: 95.6 bits;  conditional E-value: 5.5e-30
                  EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.................. CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.................. RF
    ABC_tran    1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren.................. 79  
                  l+n +l++  ge+++ivG++GaGKS++l++l ++++  +G+i +dg d++++ l++lr++++++pq+p+lf+++ vr+n                  
  EEA19146.1 1100 LSNFNLNITGGERIGIVGRTGAGKSSILSTLFRMVELSSGKISIDGVDISTIGLHELRSKLAIIPQDPTLFKGT-VRSNldpfgdhsdlvlwnalrq 1195
                  6899**********************************************************************.********************** PP

                  .........HHHTCHHHHHHHSTTGG...TTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                  .........xxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran   80 .........esdeeiekalsklglke...lkdtvvksspssLSgGqkqrvalarallkkpkllllDEpt 136 
                            sd++++ka ++l  +    + d++v ++++++S Gq+q +al ral++++k++++DE t
  EEA19146.1 1196 sclipldpsSSDSDLDKADTSLPRSLnrvTLDSPVADEGQNFSLGQRQLLALSRALVRDSKIIVIDEGT 1264
                  *99999999666666666666555444446778888999****************************88 PP

>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   1.8      0.09        55       8      89 ..     115     204 ..     108     207 .. 0.77
   2 !   68.5   7.7   1.2e-21   7.1e-19      95     274 .]     235     411 ..     226     411 .. 0.94
   3 !   90.4  15.8   2.4e-28   1.5e-25       2     270 ..     772    1032 ..     771    1036 .. 0.93

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.09
                   HHHHHHHHHHHHHHHHHHHHHHHSSTCCHH.........HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTH CS
  ABC_membrane   8 ailagvlsplfplvlgrildtlldkgdpet.........ealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpm 89 
                    +la++  ++ p+ l ++l ++ d+ d+            + + + + ++++ ++q++++   +y  + +g+++++ l + +f k ++++ 
    EEA19146.1 115 RMLADLFVVFAPFTLRYLLIFVQDSYDA-RmdvssspfiGKGIGLVVGIIVMQVLQSLTNCHFQYRSMLVGGQTRSVLISAIFTKSMKLSN 204
                   5667777777777777777777665222.2355567777788889999999999*********************************9975 PP

  == domain 2  score: 68.5 bits;  conditional E-value: 1.2e-21
                   SCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHH CS
  ABC_membrane  95 nsvGellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgir 191
                    + G+++++++nd++++ ++   ++ +++ +++++++++++++ l  + +l ++ail++ ++   ++ ++l++ ++  +  ++++ s+++E+l+ ir
    EEA19146.1 235 WTDGRIVNLMSNDTQRIFQASKVFHYVWSSPISIILAIILLVINLTYS-ALPGIAILVIGLVGVTYVVRTLSRRRDIINGITDQRISLTQEILQSIR 330
                   567*********************************999999999997.9*********************************************** PP

                   HHHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSTHHHHHHHHHHHHHHHHHH CS
  ABC_membrane 192 tVkafgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttlvisgelsvgdlvvflslfailfgal 274
                    Vk+f++e+ f+++ ++ + ++ ++    ++++++l++++++++ ++++la+   t+   +++l+   ++  l+lf+ l ++l
    EEA19146.1 331 FVKYFAWEKSFQSRLTDIRAKEIHSIQILLTIRSALGAVAMAIPIFANMLAYI--TYSLTDHNLNAAVVFSSLALFNCLRTPL 411
                   ***************************************************44..66666889**************999886 PP

  == domain 3  score: 90.4 bits;  conditional E-value: 2.4e-28
                    HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHHHHSC CS
  ABC_membrane    2 iliillailagvlsplfplvlgrildtlldkgdpetealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsffdtns 96  
                    i i++l++   +++++++l+l+++ ++ ++  + +     +y+ ++++l+++q++l +  s   ++ g r+sk+l   +  k+lr p+sffdt++
    EEA19146.1  772 IGIFVLLVTFRGANIMTSLWLSYWSEDQFS-LSRN-----QYIGIYAALAVLQGLLLFSFSAATSIFGTRASKKLLEIATWKVLRTPVSFFDTTP 860 
                    567888888899****************98.4444.....49***************************************************** PP

                    HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHH CS
  ABC_membrane   97 vGellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgir 191 
                     G+++ r+t+d++ +++ l++ l + +  ++++++++++ + +   +++++++++  +++++a++    ++lk+ e+   + +++ ++E+l+g+ 
    EEA19146.1  861 LGRITRRFTKDIDWMDNNLTDALRMYLVVFSMIISTFVLTIAYFYFFAIAIIPLACALLIWTAYYRASARELKRYESLLDSSMYARFTEALTGVP 955 
                    *********************************************************************************************** PP

                    HHHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT.TSSTHHHHHHHHHHHHHH CS
  ABC_membrane  192 tVkafgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttlvis.gelsvgdlvvflslfail 270 
                     V+a+  + +f+++   a+e++ +a++     +++l+++++++g+++++++   G+   i+  ++s++    +ls++  l
    EEA19146.1  956 CVRAYELQGQFTTRLISAIEDMGSAQFLTFGNERWLSVRLDAIGNTLVLVT---GILVLIDrYNISPSISGLILSYSLSL 1032
                    ************************************************999...55544442577777777777777654 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.1   2.3e-05     0.014      20      63 ..     507     554 ..     499     687 .. 0.77
   2 !    8.9   0.1     0.003       1.8      25     127 ..    1111    1251 ..    1100    1276 .. 0.55

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 2.3e-05
      AAA_16  20 rsgrpelvllsGesGvGKsslvrellralekd.........ggiflrgkcdql 63 
                  +gr+elv ++G+ G+GK+sl+ ++  +++k+         +     + c q+
  EEA19146.1 507 TAGRGELVAIVGAVGSGKTSLLSAIVGEMRKTsgqiilggsK-----AYCPQH 554
                 67999*******************999999994433333322.....333333 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.003
      AAA_16   25 elvllsGesGvGKsslvrellralekd.............................ggif...lrgkcdqlesaipy.....salaqalareellrq 84  
                  e + ++G  G GKss++ +l+r +e +                               +f   +r + d       +     ++l++al r + l  
  EEA19146.1 1111 ERIGIVGRTGAGKSSILSTLFRMVELSsgkisidgvdistiglhelrsklaiipqdPTLFkgtVRSNLDP------FgdhsdLVLWNAL-RQSCLIP 1200
                  556699***************9666665566666666666655555554444444212222223333333......1333224466666.4355555 PP

      AAA_16   85 lldeaesaeleawrekleeala...avpelagaea........srllellkrll 127 
                  l+  +++++l+ +++ l+++l+       +++ +         +r l +l+r+l
  EEA19146.1 1201 LDPSSSDSDLDKADTSLPRSLNrvtL---DSPVADegqnfslgQRQLLALSRAL 1251
                  55555666666666666666664431...2222223334444444444444444 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       3.4   2.1e+03      13      42 ..     189     221 ..     188     297 .. 0.81
   2 !   11.7   0.3   0.00034      0.21       2      26 ..     514     538 ..     513     544 .. 0.86
   3 !   14.4   0.1   4.8e-05      0.03       1      22 [.    1112    1133 ..    1112    1157 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 3.4
                 HHHHHHHHTS...TEEESSSTTSSSSEEEEEEE CS
    MMR_HSR1  13 StLinaltge...kaivsdkpgtTrdinegrvk 42 
                 S Li+a++ +    +  ++++gtT + ++  ++
  EEA19146.1 189 SVLISAIFTKsmkLSNRAKIQGTTVTLKKPSIN 221
                 789999987645356778888999998887776 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 0.00034
                 EEEEESTTSSHHHHHHHHHTSTEEE CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltgekaiv 26 
                 vaivG   +GK++L++a++ge  ++
  EEA19146.1 514 VAIVGAVGSGKTSLLSAIVGEMRKT 538
                 89******************95444 PP

  == domain 3  score: 14.4 bits;  conditional E-value: 4.8e-05
                  EEEEEESTTSSHHHHHHHHHTS CS
    MMR_HSR1    1 evaivGrpNvGKStLinaltge 22  
                  +++ivGr+ +GKS+++++l++ 
  EEA19146.1 1112 RIGIVGRTGAGKSSILSTLFRM 1133
                  69*****************985 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.4   0.5   0.00034      0.21       2      19 ..     514     531 ..     513     547 .. 0.90
   2 ?    0.2   0.0      0.87   5.4e+02     237     302 ..     608     670 ..     588     671 .. 0.84
   3 !    8.2   0.1    0.0031       1.9       3      30 ..    1114    1135 ..    1113    1184 .. 0.76
   4 ?    4.4   0.1     0.043        27     236     265 ..    1236    1262 ..    1198    1268 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00034
      AAA_21   2 nvliGpNgsGKSnLLdal 19 
                  +++G+ gsGK++LL a+
  EEA19146.1 514 VAIVGAVGSGKTSLLSAI 531
                 68***************9 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.87
      AAA_21 237 lSdGtkrllalltallralkkgsllliDEpEngLHPkllrrll.....ellkelsrngaQviltTHSplll 302
                 lS G+k+ + l+ a++ +    +++l D+p +  + ++ r++l     +llk +sr     il+TH+ ++l
  EEA19146.1 608 LSGGQKQRINLARAIYFQS---DIILMDDPLSAVDAHVGRHILenaicGLLKGKSR-----ILATHQLHVL 670
                 5999999999999999988...9*************99999988555667788888.....9999999887 PP

  == domain 3  score: 8.2 bits;  conditional E-value: 0.0031
      AAA_21    3 vliGpNgsGKSnLLdaldllarldrdve 30  
                  +++G+ g+GKS++L +l  +      ve
  EEA19146.1 1114 GIVGRTGAGKSSILSTLFRM------VE 1135
                  69***************444......33 PP

  == domain 4  score: 4.4 bits;  conditional E-value: 0.043
      AAA_21  236 elSdGtkrllalltallralkkgsllliDE 265 
                  ++S G+++llal  al r+    ++++iDE
  EEA19146.1 1236 NFSLGQRQLLALSRALVRDS---KIIVIDE 1262
                  57***************999...9*****9 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   1.9e-05     0.011      12      89 ..     507     582 ..     497     586 .. 0.81
   2 ?    3.5   0.1     0.062        38      21      47 ..    1115    1141 ..    1112    1150 .. 0.76
   3 ?    0.6   0.0      0.48     3e+02      77     134 ..    1238    1295 ..    1225    1303 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.9e-05
  Zeta_toxin  12 sqerPklillgGqpGAGKselaellkdelerqgnvvrldpDdlRelhPeyeeilkadpkkaseltqkdaselvekllq 89 
                 +  r  l+ ++G+ G+GK++l++++  e++++++ + l     +++ P+ + i++   +++ +  +++  e+ +++++
  EEA19146.1 507 TAGRGELVAIVGAVGSGKTSLLSAIVGEMRKTSGQIILG--GSKAYCPQHAWIQNTTIRDNIIFGKPFDPEWYQRVVE 582
                 556777999********************7666666555..5689999999999999999999999999999888876 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.062
  Zeta_toxin   21 lgGqpGAGKselaellkdelerqgnvv 47  
                  ++G +GAGKs++++ l + +e  ++ +
  EEA19146.1 1115 IVGRTGAGKSSILSTLFRMVELSSGKI 1141
                  789*********998877666555555 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.48
  Zeta_toxin   77 qkdaselvekllqeaiengyniivegtlrspdvvkklaealkkaGYevevvvvavkke 134 
                  +   ++l +  ++ + + ++ +i egt +  ++++k++++  + G++ + ++  +++ 
  EEA19146.1 1238 SLGQRQLLALSRALVRDSKIIVIDEGTSSVDQDTDKQVQRTIQHGFKGKTILSVAHRL 1295
                  555566666667778899999***************88888888*9987766665555 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.6   0.0   0.00095      0.59      20      39 ..     512     531 ..     494     533 .. 0.81
   2 !    8.8   0.3    0.0034       2.1      23      37 ..    1114    1128 ..    1098    1133 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00095
      AAA_23  20 gltlItGpNGaGKTTildAi 39 
                  l++I+G  G+GKT++l Ai
  EEA19146.1 512 ELVAIVGAVGSGKTSLLSAI 531
                 599****************9 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0034
      AAA_23   23 lItGpNGaGKTTild 37  
                   I+G +GaGK++il 
  EEA19146.1 1114 GIVGRTGAGKSSILS 1128
                  6************95 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.2   0.1    0.0017         1      98     130 ..     510     542 ..     484     546 .. 0.83
   2 !   10.1   0.3   0.00093      0.57     101     131 ..    1112    1142 ..    1099    1147 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0017
                  TTSEEEEECSTTSSHHHHHHHHCTT-----S-- CS
  RsgA_GTPase  98 kdktsvlvGqSGvGKStLinallpelelktgev 130
                  +++++++vG  G GK++L+ a+++e++   g++
   EEA19146.1 510 RGELVAIVGAVGSGKTSLLSAIVGEMRKTSGQI 542
                  45899*******************988776665 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00093
                   EEEEECSTTSSHHHHHHHHCTT-----S--- CS
  RsgA_GTPase  101 tsvlvGqSGvGKStLinallpelelktgevs 131 
                    + +vG +G+GKS+++ +l    el+ g++s
   EEA19146.1 1112 RIGIVGRTGAGKSSILSTLFRMVELSSGKIS 1142
                   56689***************99999999998 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   0.4   0.00082      0.51      25      49 ..     512     533 ..     499     684 .. 0.90
   2 ?    4.9   0.1     0.024        15      28      49 ..    1114    1134 ..    1105    1146 .. 0.84
   3 !    6.8   0.0    0.0065         4     111     211 ..    1141    1307 ..    1128    1312 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00082
                 SEEEEEESTTSSHHHHHHHHHHHCT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  25 sftaivGpNGSGKsnlldAilFvLG 49 
                 ++ aivG+ GSGK++ll Ai    G
  EEA19146.1 512 ELVAIVGAVGSGKTSLLSAI---VG 533
                 6789****************...45 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.024
                  EEEESTTSSHHHHHHHHHHHCT CS
                  xxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N   28 aivGpNGSGKsnlldAilFvLG 49  
                   ivG+ G+GKs++l  + F + 
  EEA19146.1 1114 GIVGRTGAGKSSILSTL-FRMV 1134
                  69************998.7665 PP

  == domain 3  score: 6.8 bits;  conditional E-value: 0.0065
                  EEETTEEE-HHHHHHHHHCTT-STT......................................................................CS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxx......................................................................xx RF
       SMC_N  111 ykingkevtkkevsellesagiske......................................................................lL 137 
                  + i+g +++   ++el ++  i ++                                                                      ++
  EEA19146.1 1141 ISIDGVDISTIGLHELRSKLAIIPQdptlfkgtvrsnldpfgdhsdlvlwnalrqsclipldpsssdsdldkadtslprslnrvtldspvadegqNF 1237
                  5555555555555555555555555666666666666666666666666666666666666666666666666667777777777777777777799 PP

                  -HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC-SCEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  138 SgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQfivislreemlekadklvgv 211 
                  S G+++L+al+       v+ + + ++De  +  D+   k+v + +++  k   ++ +++r +++ + d+++ +
  EEA19146.1 1238 SLGQRQLLALSRA----LVRDSKIIVIDEGTSSVDQDTDKQVQRTIQHGFKGKTILSVAHRLHTVLNYDRICVM 1307
                  99*****998754....579999**************************************9999998887655 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.0   0.1   0.00091      0.56      22      42 ..     510     531 ..     498     535 .. 0.79
   2 !    7.6   0.2    0.0052       3.2      24      39 ..    1112    1127 ..    1101    1134 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00091
      AAA_29  22 kg.atlltGpsGsGKSTllDAi 42 
                 +g  + ++G+ GsGK++ll Ai
  EEA19146.1 510 RGeLVAIVGAVGSGKTSLLSAI 531
                 345899*************997 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0052
      AAA_29   24 atlltGpsGsGKSTll 39  
                   + ++G++G+GKS++l
  EEA19146.1 1112 RIGIVGRTGAGKSSIL 1127
                  5669**********98 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.5    0.0002      0.13       6      51 ..     500     544 ..     496     550 .. 0.79
   2 ?    5.0   0.1     0.029        18      21      45 ..    1113    1137 ..    1104    1155 .. 0.82
   3 ?   -1.0   0.0         2   1.2e+03      82     114 ..    1248    1281 ..    1219    1290 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.0002
      AAA_30   6 QaaavealltsgdrvavltGpAGtGKttalkalreaweaaggrvig 51 
                 Q + ++ +++ g  +++++G+ G+GKt +l+a++  +++  g++i+
  EEA19146.1 500 QLKSITMTAGRG-ELVAIVGAVGSGKTSLLSAIVGEMRKTSGQIIL 544
                 666776666666.599*****************9888888666654 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.029
      AAA_30   21 avltGpAGtGKttalkalreaweaa 45  
                    ++G+ G+GK+ +l++l +++e +
  EEA19146.1 1113 IGIVGRTGAGKSSILSTLFRMVELS 1137
                  5689************998888766 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 2
      AAA_30   82 grarlepgtllivDE.agmvdtkqlaallkaaek 114 
                  +ra +++++++++DE ++ vd+++ +++ + +++
  EEA19146.1 1248 SRALVRDSKIIVIDEgTSSVDQDTDKQVQRTIQH 1281
                  445667789******5677888877777777665 PP

>> MeaB  Methylmalonyl Co-A mutase-associated GTPase MeaB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.4   0.1   0.00074      0.46      19      56 ..     501     538 ..     488     544 .. 0.84
   2 !    6.6   0.2    0.0053       3.3      30      66 ..    1111    1147 ..    1100    1151 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00074
                 HHHHGGG-S-SEEEEEEE-TTSSHHHHHHHHHHHHHCT CS
        MeaB  19 lerllakaGraqvvGltGvPGaGkstlvealglelrrr 56 
                 l+ ++ +aGr + v + G  G+Gk  l++a++ e+r+ 
  EEA19146.1 501 LKSITMTAGRGELVAIVGAVGSGKTSLLSAIVGEMRKT 538
                 78999**************************9999875 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0053
                  EEEEEEE-TTSSHHHHHHHHHHHHHCTT--EEEEEE- CS
        MeaB   30 qvvGltGvPGaGkstlvealglelrrrGkrvavlavD 66  
                  +++G+ G  GaGks +++ l   +     ++++  vD
  EEA19146.1 1111 ERIGIVGRTGAGKSSILSTLFRMVELSSGKISIDGVD 1147
                  79*****************998888777777777776 PP

>> ATP-synt_ab  ATP synthase alpha/beta family, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   0.0    0.0015      0.96       9      49 ..     506     601 ..     503     845 .. 0.84
   2 ?    6.0   0.1     0.013       8.2      11      38 ..    1107    1134 ..    1102    1152 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0015
                  S-EBTT-EEEEEESTTSSHHHHHHHHHHHSSTSS.EEEEEE......................................................E CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxx......................................................x RF
  ATP-synt_ab   9 fpivqGqrtlipgafgvGktvisqslskqsnsdd.aiiyvg......................................................i 49 
                  ++ ++G+ ++i+ga g Gkt ++++++ ++++++  ii+ g                                                      i
   EEA19146.1 506 MTAGRGELVAIVGAVGSGKTSLLSAIVGEMRKTSgQIILGGskaycpqhawiqnttirdniifgkpfdpewyqrvveacalvadfkilpagdmteI 601
                  6889**********************9998887756666655666666666666555555555555555555555555555555555555555554 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.013
                   EBTT-EEEEEESTTSSHHHHHHHHHHHS CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab   11 ivqGqrtlipgafgvGktvisqslskqs 38  
                   i  G+r++i+g  g Gk+ i+++l +  
   EEA19146.1 1107 ITGGERIGIVGRTGAGKSSILSTLFRMV 1134
                   6789*****************9998875 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.9   0.1    0.0002      0.12       3      30 ..     514     541 ..     512     560 .. 0.81
   2 ?    2.5   0.1      0.15        96       3      22 ..    1113    1132 ..    1111    1143 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.0002
                 EEEEESTTCCHHHHHHHHHCT--SS-EE CS
        cobW   3 tvltGflGsGKTtLlnhllenraglkla 30 
                 + ++G +GsGKT+Ll++++ + ++ +  
  EEA19146.1 514 VAIVGAVGSGKTSLLSAIVGEMRKTSGQ 541
                 6799**************9555544444 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.15
                  EEEEESTTCCHHHHHHHHHC CS
        cobW    3 tvltGflGsGKTtLlnhlle 22  
                  ++++G  G+GK+++l++l +
  EEA19146.1 1113 IGIVGRTGAGKSSILSTLFR 1132
                  6799***********99975 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.4   0.0    0.0078       4.8       2      30 ..     514     542 ..     513     565 .. 0.80
   2 ?    6.1   0.1     0.019        12       2      38 ..    1113    1150 ..    1112    1161 .. 0.73

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0078
                 EEEESSTTSSHHHHHHCHCT-CCC-EEET CS
         Roc   2 vvlvGdsgvGKtsllkrfvedkfsekeks 30 
                 v +vG  g+GKtsll+ +v +  +++ + 
  EEA19146.1 514 VAIVGAVGSGKTSLLSAIVGEMRKTSGQI 542
                 679**************998777665554 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.019
                  EEEESSTTSSHHHHHHCHCT.-CCC-EEETTTTEEEEE CS
         Roc    2 vvlvGdsgvGKtsllkrfve.dkfsekekstigvdflt 38  
                  + +vG +g+GK+s+l+ + +  + s+ + s+ gvd++t
  EEA19146.1 1113 IGIVGRTGAGKSSILSTLFRmVELSSGKISIDGVDIST 1150
                  779************99876245566666777777665 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0     0.012       7.5      35      60 ..     503     532 ..     480     535 .. 0.76
   2 ?    5.4   0.1     0.016       9.8      44      59 ..    1115    1130 ..    1102    1133 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.012
                   GGGS-.....SEEEE--TTSSHHHHHHHHH CS
  FtsK_SpoIIIE  35 lkkma....shllvaGatgsGKStalntLi 60 
                    ++m+      + ++Ga gsGK+  l +++
    EEA19146.1 503 SITMTagrgELVAIVGAVGSGKTSLLSAIV 532
                   4455555545578************99875 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.016
                    EE--TTSSHHHHHHHH CS
  FtsK_SpoIIIE   44 vaGatgsGKStalntL 59  
                    ++G+tg GKS  l tL
    EEA19146.1 1115 IVGRTGAGKSSILSTL 1130
                    9*************98 PP

>> TrwB_AAD_bind  Type IV secretion-system coupling protein DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.3   0.00048       0.3      18      47 ..     514     543 ..     500     555 .. 0.89
   2 ?    3.3   0.3     0.051        31      17      40 ..    1112    1135 ..    1108    1143 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00048
  TrwB_AAD_bind  18 ilivGttGsGKtqalekllrairargdrai 47 
                    ++ivG++GsGKt  l++++ ++r+   ++i
     EEA19146.1 514 VAIVGAVGSGKTSLLSAIVGEMRKTSGQII 543
                    689********************9987776 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.051
  TrwB_AAD_bind   17 hilivGttGsGKtqalekllrair 40  
                      i ivG tG+GK+  l+ l r ++
     EEA19146.1 1112 RIGIVGRTGAGKSSILSTLFRMVE 1135
                     688****************99886 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   0.4     0.019        12       6      25 ..     512     531 ..     507     552 .. 0.87
   2 ?    6.0   0.2     0.022        14      10      30 ..    1115    1135 ..    1109    1295 .. 0.75

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.019
      AAA_22   6 gilvvtGesGtGKTtllrrl 25 
                  +++++G +G+GKT ll  +
  EEA19146.1 512 ELVAIVGAVGSGKTSLLSAI 531
                 5789***********99766 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.022
      AAA_22   10 vtGesGtGKTtllrrlleqld 30  
                  ++G +G+GK+  l +l++  +
  EEA19146.1 1115 IVGRTGAGKSSILSTLFRMVE 1135
                  89************9999864 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.1    0.0008      0.49     130     161 ..     512     543 ..     489     545 .. 0.82
   2 ?    1.4   0.2      0.22   1.4e+02     134     160 ..    1115    1141 ..    1101    1156 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0008
       T2SSE 130 glilvsGgTgsGKttllyallkeinksderiv 161
                  l+ + G+ gsGKt ll a++ e+ k++ +i+
  EEA19146.1 512 ELVAIVGAVGSGKTSLLSAIVGEMRKTSGQII 543
                 456789********************998887 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.22
       T2SSE  134 vsGgTgsGKttllyallkeinksderi 160 
                  + G Tg GK+ +l +l  +++ s+ +i
  EEA19146.1 1115 IVGRTGAGKSSILSTLFRMVELSSGKI 1141
                  779*************99998776666 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.3      0.03        18      32      60 ..     510     538 ..     501     548 .. 0.82
   2 ?    5.9   0.0     0.014       8.4      28      58 ..    1105    1135 ..    1101    1149 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.03
       AAA_7  32 nkkpvllvGptGtGKtviikdllkkldke 60 
                 ++  v +vG +G+GKt++++ ++ ++ k+
  EEA19146.1 510 RGELVAIVGAVGSGKTSLLSAIVGEMRKT 538
                 5667899************9998888755 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.014
       AAA_7   28 lllknkkpvllvGptGtGKtviikdllkkld 58  
                  l ++ +  + +vG tG GK++i+++l++ ++
  EEA19146.1 1105 LNITGGERIGIVGRTGAGKSSILSTLFRMVE 1135
                  55677788889*************9887655 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.0     0.014       8.5       2      35 ..     498     532 ..     497     698 .. 0.86
   2 ?    0.8   0.1      0.61   3.7e+02      11      32 ..    1107    1128 ..    1101    1140 .. 0.85
   3 ?    1.3   0.0       0.4   2.5e+02     119     148 ..    1252    1281 ..    1215    1292 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.014
                 HHHHHHHHHHH.TTCEEEEEESTTSSHHHHHHHHH CS
                 xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   2 diQaeaiplil.gggdvlvaaeTGsGKTlaflipv 35 
                 + Q ++i  +  +g+ v + +++GsGKT   +  v
  EEA19146.1 498 PFQLKSITMTAgRGELVAIVGAVGSGKTSLLSAIV 532
                 679999999995667888**********9876555 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.61
                  HHTTCEEEEEESTTSSHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   11 ilgggdvlvaaeTGsGKTlafl 32  
                  i gg+ + + ++TG+GK+ + +
  EEA19146.1 1107 ITGGERIGIVGRTGAGKSSILS 1128
                  67899999*********98755 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.4
                  CTTEEEEEEETHHHHHHTTTHHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  119 lsqvrflVlDEadrlldqgfsdfinrilnq 148 
                  +++ +++V+DE     dq+  ++++r +++
  EEA19146.1 1252 VRDSKIIVIDEGTSSVDQDTDKQVQRTIQH 1281
                  677899***************999998876 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.2   0.00095      0.58       2      26 ..     513     537 ..     512     541 .. 0.88
   2 ?    0.8   0.1      0.66   4.1e+02       4      21 ..    1114    1131 ..    1111    1142 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00095
                 CEEEEC-TTTCHHHHHHHHHHHHCT CS
       NACHT   2 lvilqGeaGsGKTtLlqklalawae 26 
                 lv++ G+ GsGKT Ll  ++ ++++
  EEA19146.1 513 LVAIVGAVGSGKTSLLSAIVGEMRK 537
                 799****************988776 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.66
                  EEEC-TTTCHHHHHHHHH CS
       NACHT    4 ilqGeaGsGKTtLlqkla 21  
                   + G+ G GK+  l  l 
  EEA19146.1 1114 GIVGRTGAGKSSILSTLF 1131
                  689*********999886 PP

>> MobB  Molybdopterin guanine dinucleotide synthesis protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.2    0.0016      0.96       2      27 ..     514     539 ..     513     544 .. 0.88
   2 ?    2.0   0.1      0.28   1.7e+02       2      29 ..    1113    1140 ..    1112    1146 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0016
        MobB   2 lgivgksgsGKTtLleklipelkarg 27 
                 ++ivg  gsGKT+Ll+ ++ e+++  
  EEA19146.1 514 VAIVGAVGSGKTSLLSAIVGEMRKTS 539
                 78*******************99865 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.28
        MobB    2 lgivgksgsGKTtLleklipelkarglr 29  
                  +givg+ g+GK ++l+ l ++++ +  +
  EEA19146.1 1113 IGIVGRTGAGKSSILSTLFRMVELSSGK 1140
                  79***************99877655555 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   1.2      0.05        31      26      56 ..     514     543 ..     512     544 .. 0.89
   2 ?   10.0   0.3    0.0011      0.69      24      45 ..    1111    1132 ..    1102    1143 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.05
       DUF87  26 lAilgsTGsGKSntvavLleellekkgatil 56 
                 +Ai+g  GsGK+ + + ++ e+  k +++i+
  EEA19146.1 514 VAIVGAVGSGKTSLLSAIVGEMR-KTSGQII 543
                 79******************999.7777777 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.0011
       DUF87   24 rHlAilgsTGsGKSntvavLle 45  
                  ++++i+g+TG+GKS   + L++
  EEA19146.1 1111 ERIGIVGRTGAGKSSILSTLFR 1132
                  679*************999986 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.1     0.026        16      25      43 ..     513     531 ..     500     535 .. 0.86
   2 ?    4.3   0.0     0.044        27      28      64 ..    1115    1147 ..    1100    1216 .. 0.83

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.026
      AAA_15  25 ltvliGkNnsGKSsileal 43 
                 l  ++G+ +sGK+s+l a+
  EEA19146.1 513 LVAIVGAVGSGKTSLLSAI 531
                 899**************99 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.044
      AAA_15   28 liGkNnsGKSsilealdlFlnnkekknkkvikieked 64  
                  ++G+ ++GKSsil  l  + + +    + +i i+  d
  EEA19146.1 1115 IVGRTGAGKSSILSTLFRMVELS----SGKISIDGVD 1147
                  8*************998888877....4444455444 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.0    0.0049         3      31      57 ..     509     535 ..     490     555 .. 0.84
   2 ?    0.7   0.1      0.53   3.3e+02      33      53 ..    1110    1130 ..    1106    1140 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0049
      AAA_25  31 pagelallaGapgtGKttlaldlalav 57 
                  +gel++++Ga g+GKt l++ ++ ++
  EEA19146.1 509 GRGELVAIVGAVGSGKTSLLSAIVGEM 535
                 689****************99887665 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.53
      AAA_25   33 gelallaGapgtGKttlaldl 53  
                  ge + ++G++g+GK+ +++ l
  EEA19146.1 1110 GERIGIVGRTGAGKSSILSTL 1130
                  7778899*********99877 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.5    0.0046       2.9      21      48 ..     512     539 ..     501     542 .. 0.84
   2 ?    3.9   0.3     0.041        26      23      43 ..    1113    1133 ..    1105    1142 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0046
                 EEEEEEESTTSSHHHHHHHHCCSHCCCC CS
      NB-ARC  21 lvvalvGmgGvGKttlakqilnksdeve 48 
                  +va+vG  G+GKt l++ i+ ++ ++ 
  EEA19146.1 512 ELVAIVGAVGSGKTSLLSAIVGEMRKTS 539
                 479*****************99877665 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.041
                  EEEEESTTSSHHHHHHHHCCS CS
      NB-ARC   23 valvGmgGvGKttlakqilnk 43  
                  +++vG+ G GK+ +++  ++ 
  EEA19146.1 1113 IGIVGRTGAGKSSILSTLFRM 1133
                  89*************999886 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.8   0.00047      0.29       1      24 [.     514     537 ..     514     545 .. 0.85
   2 ?    5.1   0.7     0.035        22       1      19 [.    1113    1131 ..    1113    1142 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00047
                 EEEEEBTTTTHHHHHHHHHTS--S CS
   Dynamin_N   1 iavvGsqSsGKSSvlnaLlgedil 24 
                 +a+vG++ sGK+S+l a++ge   
  EEA19146.1 514 VAIVGAVGSGKTSLLSAIVGEMRK 537
                 79******************9755 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.035
                  EEEEEBTTTTHHHHHHHHH CS
   Dynamin_N    1 iavvGsqSsGKSSvlnaLl 19  
                  i +vG + +GKSS+l  L 
  EEA19146.1 1113 IGIVGRTGAGKSSILSTLF 1131
                  789************8886 PP

>> PgaD  PgaD-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.5      0.11        70      46      96 ..     785     829 ..     768     844 .. 0.73
   2 ?    7.9   0.6    0.0047       2.9      67     119 ..     896     946 ..     878     949 .. 0.77

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.11
        PgaD  46 elfeaeillglfseasasevegslseletlrlYalilvviavlLilWakln 96 
                 +++++ +l      ++ se + sls  + +++Ya+ +v+ ++lL+ +++  
  EEA19146.1 785 NIMTSLWL------SYWSEDQFSLSRNQYIGIYAALAVLQGLLLFSFSAAT 829
                 33333333......5667778888999*****************9988765 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0047
        PgaD  67 gslseletlrlYalilvviavlLilWaklnrvrfkakkrrvkapalddeelAk 119
                 +++ +++ + ++a++++ +a  L++W ++ r  +++ k r  +  ld   +A+
  EEA19146.1 896 TFVLTIAYFYFFAIAIIPLACALLIWTAYYRASARELK-R-YESLLDSSMYAR 946
                 56678888999******************888666664.4.456667777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1348 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1132  (0.0631379); expected 358.6 (0.02)
Passed bias filter:                      681  (0.0379832); expected 358.6 (0.02)
Passed Vit filter:                       106  (0.00591221); expected 17.9 (0.001)
Passed Fwd filter:                        32  (0.00178482); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              29  [number of targets reported over threshold]
# CPU time: 1.05u 0.30s 00:00:01.35 Elapsed: 00:00:00.48
# Mc/sec: 8380.11
//
Query:       EEA19147.1  [L=629]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.4e-10   39.1   0.0    2.9e-09   37.4   0.0    2.0  2  ATPgrasp_N       ATP-grasp N-terminal domain
    1.6e-09   37.5   0.1    7.9e-09   35.3   0.1    2.1  1  ATP-grasp_4      ATP-grasp domain
    3.7e-08   33.1   0.0    1.9e-07   30.8   0.0    1.9  2  Dala_Dala_lig_C  D-ala D-ala ligase C-terminus
    0.00093   19.3   0.0     0.0024   17.9   0.0    1.6  1  ATP-grasp_3      ATP-grasp domain
     0.0041   16.5   0.0     0.0073   15.7   0.0    1.3  1  GSH-S_ATP        Prokaryotic glutathione synthetase, ATP-gras
  ------ inclusion threshold ------
       0.17   11.4   0.0       0.84    9.2   0.0    2.0  3  RimK             RimK-like ATP-grasp domain


Domain annotation for each model (and alignments):
>> ATPgrasp_N  ATP-grasp N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.4   0.0   9.7e-13   2.9e-09       3      82 .]     188     268 ..     186     268 .. 0.89
   2 ?   -3.8   0.0         6   1.8e+04      31      41 ..     548     558 ..     547     566 .. 0.81

  Alignments for each domain:
  == domain 1  score: 37.4 bits;  conditional E-value: 9.7e-13
                 HHHHTT-EEEEEEETTS-..---S-TT.EEEEEEE-TTT-HHHHHHHHHHHH.HHS--SEEE---GGGHHHHHHHHHHTT-SS CS
  ATPgrasp_N   3 aAkaLGikvvlvdeedew..apeelaelvekfipldlaqdpdaaleavrals.rerpvdGivtftdlavplvArlaeaLgLPg 82 
                  A aLG+++v+++  + w  +  el +l+e+f+++dl+  p+ a ++v+++    rp+dG+vt    ++  +Ar+a  LgLP+
  EEA19147.1 188 GAYALGLDLVILSTGS-WfsDDHELSYLREAFVVMDLSL-PGLADRIVDKMRyYGRPFDGVVTPMSDWLEQIARAADTLGLPT 268
                 699******9997765.7565556677***********7.**********99677***************************7 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 6
                 EEEEE-TTT-H CS
  ATPgrasp_N  31 kfipldlaqdp 41 
                 ++ip+dl++dp
  EEA19147.1 548 HMIPVDLKADP 558
                 689****9987 PP

>> ATP-grasp_4  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.3   0.1   2.7e-12   7.9e-09       2     139 ..     311     444 ..     310     448 .. 0.81

  Alignments for each domain:
  == domain 1  score: 35.3 bits;  conditional E-value: 2.7e-12
  ATP-grasp_4   2 slPvviKPsvgffSlGVykinneeewkaavaaieeeleqakeeykeevveeesflvEeyieGeEfavdayfdeeGepvilnilkk..........efa 89 
                   +Pvv+KP++g++S+ V k+++e+ +  av++                ++++++l+Eey++G Ef v+  +  +Ge ++ ++ +           +  
   EEA19147.1 311 TYPVVVKPVSGSASRCVFKVHDEHGLLTAVEKAA-------------NLNDTRVLIEEYVHGPEFDVNFVL-LDGEVLFSEVSDDlpsygdqltaNDF 394
                  69************************99887655.............3578999*************9888.99*****9997642222211111334 PP

  ATP-grasp_4  90 seedvsdrlyvtsakvieetlealeellkevnallglknfpvHiElrvse 139
                  +++++ ++  ++++ +  e  + +e+ +++   + g++n+++H+E r++ 
   EEA19147.1 395 DNPNFGETTVIMPTILPIEATKVIEKKFHQTLLRHGFTNGVFHVEGRLRS 444
                  4556778999999999999999999999999999***********99875 PP

>> Dala_Dala_lig_C  D-ala D-ala ligase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.8   0.0   6.3e-11   1.9e-07      36     136 ..     311     416 ..     307     429 .. 0.76
   2 ?   -0.8   0.0      0.31   9.2e+02     163     182 ..     460     480 ..     457     497 .. 0.74

  Alignments for each domain:
  == domain 1  score: 30.8 bits;  conditional E-value: 6.3e-11
                      -SSEEEEESSSSTTTTEEEESSGGGHHHHHHHHHT.T-SCEEEEE--ESEEEEEE.EEETSSCEEEEEEEEE-SS....SSS-HHHHHC.TT-E CS
  Dala_Dala_lig_C  36 gypvfVKpareGSSvGvskveseeelkeaieeafk.ydekvlvEeaiegreieva.vlgneklevsevgeivvkk....gfydyeakysddkaq 123
                      +ypv+VKp+    S  v kv+ e+ l  a+e+a++  d++vl+Ee+++g e++v  vl ++++  sev +  ++     +  d+++ +   +++
       EEA19147.1 311 TYPVVVKPVSGSASRCVFKVHDEHGLLTAVEKAANlNDTRVLIEEYVHGPEFDVNfVLLDGEVLFSEVSDDLPSYgdqlTANDFDNPNF-GETT 403
                      7*********99*******************99873699***************84566888888888776666544444555555544.4555 PP

                      EESS----HHHHH CS
  Dala_Dala_lig_C 124 levpaklekevee 136
                      + +p+ l+ e ++
       EEA19147.1 404 VIMPTILPIEATK 416
                      5556655555555 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.31
                      TTTEEEEEEEESS.---STTS CS
  Dala_Dala_lig_C 163 eegeivlnEvNtl.PGfTeiS 182
                      ++ +++l EvN   PG+ + S
       EEA19147.1 460 TNTSVYLHEVNARpPGYNSSS 480
                      56789******9735777666 PP

>> ATP-grasp_3  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.0     8e-07    0.0024      30      86 ..     310     373 ..     294     383 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 8e-07
                  -SSSEEEEESS-------B--SS--TTE..............EEEE---SEEEEEEEEE.SSSE CS
  ATP-grasp_3  30 eekklvvKprdGaggesvrvveekeeaeaaieeve.......lvqefieGkplSvsllsdgekv 86 
                    +++vvKp++G+++  v++v++++ + +a+e+ +       l+ e++ G ++ v+++    +v
   EEA19147.1 310 TTYPVVVKPVSGSASRCVFKVHDEHGLLTAVEKAAnlndtrvLIEEYVHGPEFDVNFVLLDGEV 373
                  5799********************99999999888999******************98755555 PP

>> GSH-S_ATP  Prokaryotic glutathione synthetase, ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   2.5e-06    0.0073      32      96 ..     312     374 ..     292     388 .. 0.85

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 2.5e-06
                 SSEEEEESS--TTTT-EEE-TT-TTHHHHHHHHTTTTTS-EEEEE--GGGGG-EEEEEEETTEE- CS
   GSH-S_ATP  32 gdvilKPldgkgGegvfrvkksdpnlksilellteegkepviaqrylpeikeGDkRillvdGepi 96 
                   v++KP++g++ + vf+v++ ++ l + +e  ++ + + v++ +y++  +  D+ ++l+dGe +
  EEA19147.1 312 YPVVVKPVSGSASRCVFKVHD-EHGLLTAVEKAANLNDTRVLIEEYVHGPEF-DVNFVLLDGEVL 374
                 569****************98.66777788999999999********98765.*********987 PP

>> RimK  RimK-like ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.0       2.7     8e+03      11      36 ..     160     185 ..     155     190 .. 0.72
   2 ?    9.2   0.0   0.00028      0.84      25      99 ..     296     373 ..     288     377 .. 0.80
   3 ?   -1.9   0.0      0.73   2.2e+03     153     168 ..     459     474 ..     453     489 .. 0.71

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 2.7
                 HHHTT-----EEEESS-S-HHHHHHT CS
        RimK  11 Lakakikvpntalardeedaekliek 36 
                 L+ ++i+  + a++ ++ d++++i +
  EEA19147.1 160 LLSKPIPRRRIAMVSEPTDVVATIRR 185
                 66677777778888888887777754 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00028
                 SS-S-HHHHHHTT-.-SSEEEEE-TTTT--EEEEE-SHHHHHHHHHH....GGG--EEEEE--SS-SEEEEEEEETTEE CS
        RimK  25 rdeedaekliekiklrfPvvvKsvegsqGikvvlakkeqklkqvlea....lkeailvqeyieeaenediRvlvvddev 99 
                  + +d+ + ++ ++   PvvvK v gs    v+  ++e  l   +e      ++++l+ ey++  e  d+  + +d+ev
  EEA19147.1 296 TSVDDLGRNLPLVGTTYPVVVKPVSGSASRCVFKVHDEHGLLTAVEKaanlNDTRVLIEEYVHGPE-FDVNFVLLDGEV 373
                 5667777788889999**********************998888776677445678*****98654.677777777776 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 0.73
                 EETTEEEEEEEESS-- CS
        RimK 153 rakrgllvlEvnsspg 168
                 +++ ++++ Evn+ p 
  EEA19147.1 459 KTNTSVYLHEVNARPP 474
                 678999*******874 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (629 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       366  (0.0204139); expected 358.6 (0.02)
Passed bias filter:                      353  (0.0196888); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.64u 0.30s 00:00:00.94 Elapsed: 00:00:00.48
# Mc/sec: 3956.43
//
Query:       EEA19148.1  [L=318]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.1e-28   98.2   0.0    6.4e-28   97.9   0.0    1.2  1  NAS       Nicotianamine synthase protein


Domain annotation for each model (and alignments):
>> NAS  Nicotianamine synthase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.9   0.0   3.6e-32   6.4e-28      54     248 ..      88     287 ..      35     299 .. 0.84

  Alignments for each domain:
  == domain 1  score: 97.9 bits;  conditional E-value: 3.6e-32
         NAS  54 gqevqeileeLirlcseaeglLeshyskllaafe...nPldhleiFPyyknYlkLsklEyellskkvtevPtkvaFiGsGPlPltslvla.skhlskti 148
                  +++++i+ +L+++ s+ e   e+ ++k + +     +  ++l ++P  + Y  L  lE+++  + +++ P+k+a iGsGPlPlt + ++ +   +  +
  EEA19148.1  88 DDRIKSIVPNLRQIFSDVECAYEEVWAKKINTCPnssEAQKVLLTYPMLHVYDFLVSLEWNAARTILQDFPSKIAMIGSGPLPLTPMRIIdAARKQGHT 186
                 489***************************987612256789********************9999999*****************9888344455677 PP

         NAS 149 fdnlDkdglandkasklvsadedlssrmsfhtadvldvt..eelkaydvvflAAlvGmakeeKakviehlakkmakGavlvlrsahGarafLypvvdpe 245
                 ++++       d+ +  v++ ++l+     +t +v d++   +l+a+d v++A lvG ++++K++++  + k m++Gav+++r+ +G+++++yp vdp 
  EEA19148.1 187 IEQFHLIERYADRVECSVNSVNKLGGY-ESITHEVGDAAdpGDLTAFDAVYVAILVGETEKQKEELLLGILKRMKPGAVVITRGSRGLKGLIYPEVDPL 284
                 888888888888888888888888533.334555555541159******************************************************98 PP

         NAS 246 dlk 248
                  l+
  EEA19148.1 285 SLR 287
                 776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (318 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       416  (0.0232026); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2237.64
//
Query:       EEA19149.1  [L=1709]
Description: nonribosomal peptide synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.1e-76  256.3   0.0    5.7e-76  255.8   0.0    1.2  1  AMP-binding   AMP-binding enzyme
    4.3e-50  170.7   5.4    2.8e-24   85.6   0.8    3.8  2  Condensation  Condensation domain
    7.5e-08   32.6   0.1    2.4e-07   31.0   0.1    1.9  1  PP-binding    Phosphopantetheine attachment site


Domain annotation for each model (and alignments):
>> AMP-binding  AMP-binding enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  255.8   0.0   9.5e-80   5.7e-76       3     423 .]     232     626 ..     230     626 .. 0.86

  Alignments for each domain:
  == domain 1  score: 255.8 bits;  conditional E-value: 9.5e-80
                  HHHHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEEEE CS
  AMP-binding   3 eqaaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakvlia 100
                  ++a+++p + a+     + +++++eld+ ++rlA  L++ Gv +g+ + + +++s+  v++++ailk G + vpl  t++  +   i+++s+ak ++ 
   EEA19149.1 232 KWAKTQPFAEAICA--PDGSFSFSELDSLSSRLAYRLQQQGVHPGELIPLGMERSALAVITMIAILKTGSAFVPLEVTSPIGRNLEIVKQSGAKRVL- 326
                  67999999999977..999*******************99*********************************************************. PP

                  TCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHH.HHHCS CS
  AMP-binding 101 tvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslk.letrf 197
                   +++ +     ++ ++     ++  l + e+       ++   +++     + + ++ ++lay+i+TSG+TGkPKGVm++h +l+a+v+s +  + +f
   EEA19149.1 327 -ISESQ---TTKDWPA-----EISALVTLEMI-----RSTP-FPDA---G-TLPCVDLQSLAYVIFTSGSTGKPKGVMIEHHSLSASVRS-ErQPYTF 404
                  .54444...2222222.....22222222222.....2222.2222...2.445799*********************************.6344447 PP

                  CCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEEEESS-E CS
  AMP-binding 198 klkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvllggepl 295
                  + +   + l++++la+++++ +e l++l++G++v +++++++ld  +l+e++++ +++  + +P++++ l  +  ++      +l+ l++v+lgge++
   EEA19149.1 405 NQSTATRALQFASLAFDASF-AEHLAPLSNGGCVFIPDQETRLD--RLVEFMNRNRINWAFFTPSFFRLL--D--PD------ELPWLKTVVLGGEAI 489
                  777799*************9.***********999999888877..899*******************99..2..34......7899*********** PP

                  BHHHHHHHHHHHTCEEEEEEEEGGGSSECEE..CHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBE.ETTSEEEEEEEETTS-SEBTT-HHHHHHHEE CS
  AMP-binding 296 spellrffralfgeevlegYGlTEttgvvtv..lpleedkkklgsvGkplpgvevkivDeetgepv.pdgeeGellvrgpgvmkgYlkkpeataeafd 390
                  + ++++++  +   ++++gYG++Ett++vt   ++ ++++ ++ s+G+ +   +v +vD+e++  + p g++Gell++gp+v +gYl+++ +t+ +f+
   EEA19149.1 490 NDDCIDRWAHRI--RLVNGYGPSETTICVTAcvVD-PGSE-NRASIGTGMIS-KVWVVDPEDLDQLsPIGTVGELLIQGPTVGRGYLGDETRTKASFI 582
                  ***********7..49*************555433.4453.45689999766.999****998887589***************************** PP

                  E...........TCCEEEEEEEEEEETTSEEEEEEECCCEEEET CS
  AMP-binding 391 s...........egrwlrTGDlgrldedGyleivgRkkdliklr 423
                  +           ++  +rTGDl+r+++dG+l +vgR + +ik+r
   EEA19149.1 583 ErprwlrnhtehHESIYRTGDLVRFEPDGSLTYVGRRDTQIKIR 626
                  8899*****974256***************************96 PP

>> Condensation  Condensation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.6   0.8   4.7e-28   2.8e-24       4     431 ..     851    1249 ..     848    1259 .. 0.75
   2 !   82.1   0.3   5.5e-27   3.3e-23       4     437 ..    1295    1707 ..    1292    1709 .] 0.78

  Alignments for each domain:
  == domain 1  score: 85.6 bits;  conditional E-value: 4.7e-28
                    EEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T..TSSSHHHH CS
  Condensation    4 eyplspaQkrmwflekleeessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvileerevelevleisdleeseeeea 98  
                      plsp+Q    +++    +++++ +++ lk++ +  + r+e++l+e+++rh  LR++++    + ++Q i++  +  + + +i d ++      
    EEA19149.1  851 AFPLSPIQ--KVYAKRAPSDKHHFYQAMLLKVSVGTPIPRIEESLREVVKRHSMLRVRLQPS-STGFMQEISDRLPS-VSIHHIPDYAA------ 935 
                    679*****..67777888899**************************************766.9999**99987764.34577774333...... PP

                    HHHHHHHHHTC--SCCCS-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHHHHH CS
  Condensation   99 ieefaqkdlqepfdLekgpLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskdlek 193 
                      e++ k ++e++d ++g  f+a +++ +e+rlll+l  HH+ vD vS++i++ dl ++     + + lp  + t+++++ + +q  +      k
    EEA19149.1  936 --EYVMKMSREHLDPYNGVSFHADILQ-TESRLLLFLVGHHLAVDLVSWNIIISDLEQFI----RFNHLPPFEATSFQTWCNYLQHLKP----RK 1019
                    ..344445678****************.*******************************9....5566666677779999988555444....44 PP

                    HHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEESSTT..CST CS
  Condensation  194 eeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisgRes..eik 286 
                    +  Y   ++ +  p+l+L   + +p  +  +   ++  l+++    l +++++ +++l dv+l  l l   ++  ++d+ ++ e +gRe+  + +
    EEA19149.1 1020 ALPY---TIPS--PNLDLWGMHGKPNTYG-DVIHYTTGLKHTQFTDLLSFTQNFNINLLDVFLGSLFLSFRRVF-NRDVTIHNESHGREHsnPFL 1107
                    5556...4444..8999999933333333.2356777889999999************************9996.57899**********9999* PP

                    CHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HH....CCCEEECCCCSEE CS
  Condensation  287 diermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgq....eseeeesqlselk 377 
                    di+ +vG+F+  lPl  ++k++ ++ e+ ++v+     +      p + L + + +   +++  +f+ vf   ny+g+      ee+ +q +   
    EEA19149.1 1108 DISGTVGWFTTLLPLAPRIKPGASLLEVSRNVQFSRTAV------PDNGLLHFTSKVLGQDEVDIFEIVF---NYMGSsfslTREESVFQIEPHS 1193
                    ***********************9999999998655555......3333333333333334455565444...4455555454444444444333 PP

                    EC..EE...E.....SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHH CS
  Condensation  378 ls..vssveaeeeskydlsleasetngkltikieYntslFdeetierflerlkell 431 
                    ++   +s++++  +   ++++a  +n + ++ ++ n+   d ++i++++     +l
    EEA19149.1 1194 VGvsGDSASNNMSRLTLIEISAAVVNHEVELVFSCNQHMTDLSSIQKWMVECASIL 1249
                    33102222234444444566666677777777777888888888888877666666 PP

  == domain 2  score: 82.1 bits;  conditional E-value: 5.5e-27
                    EEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T..TSSSHHHH CS
  Condensation    4 eyplspaQkrmwflekleeessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvileerevelevleisdleeseeeea 98  
                    +yp sp+Q+ m++++ + +es+   + + +k   ++d++r+eka++ +++ +++LRtvf+   ++   Qv+l+++ ++  + ++++   s+    
    EEA19149.1 1295 IYPTSPMQNAMLIAQASAPESYQAKLLLGIKSLDQFDISRFEKAWTMVVRDNPILRTVFVPRCTDVYDQVVLNNKIIDSGIAKAEQIFPSNL--- 1386
                    69***************98887777777778888*************************999888888999999988886666653333332... PP

                    HHHHHHHHHTC--SCCCS-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHHHHH CS
  Condensation   99 ieefaqkdlqepfdLekgpLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskdlek 193 
                      ++++    ++ ++ +  +     ++++ n +++l+++ H ++D v l+ ll  l+++Y   +   ++ +pq++ Y++++e+    l+++d  +
    EEA19149.1 1387 --ALMT----SSWKVLQ--PHNKLTITYKGNYATCLFEINHCLIDHVALQNLLCYLSETY---TGSIDTATPQVK-YENFIEH----LTQDDSLT 1465
                    ..2222....2333322..33333567799******************************...444567778888.*******....999***** PP

                    HHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEESSTT..CST CS
  Condensation  194 eeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisgRes..eik 286 
                    + +YW++ + +     +L k   ++++++++++r+    + ++ e ++++  ++  t  ++l  +++l+L+k tg+++  +g ++sgR    e+ 
    EEA19149.1 1466 SINYWRTAFPS-----TLHKS-LTSPSSNLNDNRKLRHSPISLSESVKSALVSSIHTPSTILRLCWALTLQKQTGSQNPQFGYVVSGRDVsiENT 1554
                    **********8.....44455.55666666656666666666667777777777789999*****************************967777 PP

                    CHHC--SS-EEEEEEEEE--TT-........BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-...S-SEEEEESSS-HHCCCEEE CS
  Condensation  287 diermvGlFvntlPlridvkeak........tfselikrvkedllkaephqgypleeLvkdlelqrkesrsp...Lfdpvfsfenylgqeseeee 370 
                    +  r+ G  +n+lP  id+            ++++l+++++++  +++phq   +   ++  e+qr  s+ p    fd+v++f          ++
    EEA19149.1 1555 ESGRIAGPLLNILPCTIDLGVLStvyhiakqRLQDLLEDIQTQYARSLPHQHWFFTYATEVREQQRL-SEPPtrlFFDTVVNFRR------HVSQ 1642
                    7789**************9655466777777999******************988655444444432.322222279******54......6666 PP

                    CCCCSEEECEE...E.....SSEEEEEEE..TTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHS CS
  Condensation  371 sqlselklsvssveaeeeskydlslease..tngkltikieYntslFdeetierflerlkelleqvieh 437 
                    ++ s+l+++  +++  e+ ++d ++ + +  ++ k+ti +   + + +e++ +++ + ++e +eqv ++
    EEA19149.1 1643 PETSSLEFT--IIG--ENDPFDHDVVLEIdlEETKFTIILTSWEHRVNEAMATELVRSFEESVEQVCAQ 1707
                    666666666..555..55556555555554488889988888888899999999999999999999775 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.0   0.1     4e-11   2.4e-07       3      60 ..     773     829 ..     771     834 .. 0.92

  Alignments for each domain:
  == domain 1  score: 31.0 bits;  conditional E-value: 4e-11
  PP-binding   3 lrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptl 60 
                 l++++a+vl+++   +  d +l +lG+DSl+a++++a+ ++e + +i++s l+  +++
  EEA19149.1 773 LQRIWASVLNRDSHGVPIDRSLQSLGGDSLAAIQIVAQCRKE-KMAISMSNLLRGDSI 829
                 899************99*************************.*******99987776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1709 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       565  (0.0315132); expected 358.6 (0.02)
Passed bias filter:                      506  (0.0282224); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.99u 0.26s 00:00:01.25 Elapsed: 00:00:00.44
# Mc/sec: 11666.37
//
Query:       EEA19150.1  [L=472]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.4e-15   55.2  17.6    5.4e-15   55.2  17.6    2.0  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.017   13.4   1.3      0.038   12.3   1.3    1.7  1  OATP      Organic Anion Transporter Polypeptide (OATP) family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.2  17.6     6e-19   5.4e-15      32     334 ..      85     414 ..      79     424 .. 0.71
   2 ?   -2.5   5.0      0.21   1.9e+03     222     260 ..     424     464 ..     407     472 .] 0.52

  Alignments for each domain:
  == domain 1  score: 55.2 bits;  conditional E-value: 6e-19
       MFS_1  32 seigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllll..fa.sslw..lllvlrvlqGlga..galfpagaaliadwfpkeergra 122
                 +++ +l ++ ++ a++ +lp+G +++  Gr  vl l++ + +l+ l++l+  f  ++l+  l++v+ +l ++g+   ++ +++++l++d+++ke+r++a
  EEA19150.1  85 TTQTWLKVGESVCALLVALPFGNIANTKGRSLVLTLAISGQILAdLWILAicFFnQTLPlsLVYVSPLLRSIGGgeMVMSAIIHTLLVDVVTKENRAQA 183
                 5667888888999*************************************664243333114566666555555226999999**************** PP

       MFS_1 123 igllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.............kgtgpaplvpawkallkdpv 208
                 +  +++++ ++ +++p++g++l+++ g  ++ +   ++ +  +v   ++ + ++++ +++ ++e +              + + +++v+  ++ ++  +
  EEA19150.1 184 FFNMAVMTLIAELVAPAVGSMLVDWQGVYLPLLCSFPLQVGTMV---IFGLLPDTRLPKNLEIENGcdpvegrhlteesDKGAFTNWVK--SLKRSYSP 277
                 ***********************776666666666666666666...555555555555555555555566665554443444455555..44444444 PP

       MFS_1 209 l.....willialllfffgfsg..lltllplylqevlgls....glllaglllallalvgailallagrlsdr...lgrrrrlllallllllaalglal 293
                 +     w l++++++    + +  +  +l  y+ +++ +s    ++l+++ +l  +al ++il ll+ +l+++    ++ + l++a ++ l++++g +l
  EEA19150.1 278 FqtkaiW-LVTVCYIS--TMLArdTIDFLVQYASKQFEWSlakaNYLISVKALVSMALYVLILPLLSKALVKKysmSPPIIDLWIARGSSLFGVVGPIL 373
                 4433224.33333333..444456999999999*******888855555555555555555556677777788664445999***************** PP

       MFS_1 294 lavtssavllllvlvliGfglgfvfpsllalasdlappeea 334
                 l+++s +v+l+++lvl+ f lgf f++  + +s + p e a
  EEA19150.1 374 LGMASGPVVLVIALVLFAFSLGFPFSIQVYGTSLVEPVEVA 414
                 ****99**********9999999888776655554455555 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.21
       MFS_1 222 gfsglltllplylqevlgls....glllaglllallalvgail 260
                  ++ +l ++pl+  + ++++    g   +gl++ +++ +++i+
  EEA19150.1 424 RIAVTLLTSPLL-AMAFKYGlnagG-AASGLIFDIAGGLFFIA 464
                 444455666663.444444433654.55555555555555555 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   1.3   4.3e-06     0.038     278     372 ..     266     362 ..     140     379 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 4.3e-06
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 278 kslkdfpkalkrllknpifllvilssvfeillvaGfitFlpkylEtqFslsaseAnlltGvvvipgaalGi....llgGllvkklklsakklaklvlvv 372
                 + +k++ +++    + +  +lv+++  +  +l+   i Fl +y  +qF+ s ++An l+ v +++++al +    ll+  lvkk+ +s+  +  +++  
  EEA19150.1 266 NWVKSLKRSYSPF-QTKAIWLVTVC-YISTMLARDTIDFLVQYASKQFEWSLAKANYLISVKALVSMALYVlilpLLSKALVKKYSMSPPIIDLWIARG 362
                 3444444444333.33444444444.3556677789**************************999999988556678999999*999998888887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (472 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       631  (0.0351944); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.24s 00:00:00.82 Elapsed: 00:00:00.43
# Mc/sec: 3269.96
//
Query:       EEA19151.1  [L=529]
Description: GABA permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.1e-58  196.9  47.5    6.3e-58  196.6  47.5    1.1  1  AA_permease_2  Amino acid permease
    3.7e-27   95.0  41.8    4.7e-27   94.7  41.8    1.0  1  AA_permease    Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  196.6  47.5   7.1e-62   6.3e-58       7     424 ..      59     500 ..      54     503 .. 0.85

  Alignments for each domain:
  == domain 1  score: 196.6 bits;  conditional E-value: 7.1e-62
  AA_permease_2   7 falvigsvigsg...ifvkn..laasggpalilwvwiavligslavllvyaElssalprsgGiyvytkaaf....gkkvaflsawfnwfayvpvla 93 
                    +al++ sv+ ++    +++n  ++++gg+a ++w ++ +++g+   ++ + E++s+ p+sgG+y+++++++    +k++ ++++w++++a+ ++ a
     EEA19151.1  59 AALSFASVLQATwefLLISNsqGLENGGMAGLFWSFVWTFVGFGFIIASLSEMASMAPTSGGQYHWVSEFSppryQKFLSYVTGWISVLAWQAGSA 154
                    5666666644332223445568999*****************99999999*****9**************6444489******************* PP

  AA_permease_2  94 silsvaasyllnal...gpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfsslstetdtffpn. 185
                    s++ + +  +++++   +pd++ ++w+  l+++a ++++ ++n+++ + +  ++n l +++il   ++++i +l+t  ++++       +t+f++ 
     EEA19151.1 155 SGSFLTGTIIQGLIsirNPDYTAENWQGTLFVFAMILVIYFFNVYASSLMPILNNLLLVFHIL-SWAVIVI-VLWTMAPHQSA------KTVFTHw 242
                    **99888888777634467*******************************************5.6666664.55555565554......3555555 PP

  AA_permease_2 186 ....gwpgvllglli....vlwsfdGfesaanvseevkk..kdvpkaifigllivlvlyllvniaflgvvpddeianlsnlgsvaalffeavggkv 271
                        gw+++ l+ +i    ++++    ++ a++seev+   ++vp+ai +g    +++ +++ ia+l+++p  e a ++n+g ++  +f+++ + +
     EEA19151.1 243 enlgGWSSMGLSVMIgqisAIYASLSSDATAHMSEEVQDagRNVPIAIAWGYFSNGLMAIVLLIAYLFAIPSVEDALNDNTGFPFLYVFQNAVSEA 338
                    55669999855444445669****************998789***************************************************9** PP

  AA_permease_2 272 vaiivvilialsllgaintavigssrvlealardgvlP..rffakvn.kfgspiraiiltaivslillllfllassaaynfllsvsslgliisyll 364
                    +   + ++i l ++++ + + +++sr+ +a+ard++lP  ++++kv+ k+++p++ai l++i+s++l+l+ + +s +a+n++ s+ + +l+  y++
     EEA19151.1 339 GLNGLTAIILLPVIFSNIFFNASTSRQTFAFARDKGLPfsKWISKVDtKRKIPVNAIALSCIISCLLSLINI-GSLTAFNAIISLNVAALMYTYIV 433
                    *****************************************************************9986665.579***********999999999 PP

  AA_permease_2 365 liigalilrkkrphl...kr...pgki..lvaiigalfllfllvalffppkgpatqssliytiiltva 424
                     i +++i+rk  + +   +r   +g++  +v+iig+l+++f++++  +p++ p+t ++++++++++++
     EEA19151.1 434 SI-SCVIYRKIWHAEtlpPRrwdMGRWglPVNIIGVLYCCFAFFWSLWPSELPVTVDNFNWSVVIFGG 500
                    88.555555442222245335565555559********************************887765 PP

>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.7  41.8   5.2e-31   4.7e-27      14     461 ..      73     510 ..      61     517 .. 0.84

  Alignments for each domain:
  == domain 1  score: 94.7 bits;  conditional E-value: 5.2e-31
  AA_permease  14 glfvglgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgp....elGfviGlnylfswitvlaleltaasiliqfwel. 106
                   l+++++  l ++G +g++ +++ ++v + +++ sl+e+a++ p sgg y+++s+f  p     l++v+G++ ++ w ++ a + +  + +iq + + 
   EEA19151.1  73 FLLISNSQGLENGGMAGLFWSFVWTFVGFGFIIASLSEMASMAPTSGGQYHWVSEFSPPryqkFLSYVTGWISVLAWQAGSASGSFLTGTIIQGLISi 170
                  5899****************************************************866332269******************999999999987664 PP

  AA_permease 107 .vtdlpkawvt.gavflvvllii.nlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkga..gfrflgdngsifknnlppgfakeeegafk 199
                   ++d+  a+ + g++f+++++++  +++v ++  + ++ +l+++  i++  ++ i+ l+  +p + a   f+++ + g+    + + g         +
   EEA19151.1 171 rNPDYT-AENWqGTLFVFAMILViYFFNVYASSLMPILNNLLLVFHILSWAVIVIV-LWTMAPHQSAktVFTHWENLGG----WSSMG---------L 253
                  577787.5666899999988765156788888888888777777766666666543.3333333333357888888888....77777.........8 PP

  AA_permease 200 nfisvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasaaspfvifikesgvsvlaplinavil 297
                  +++++ + ++ a  +  ++a +++Ev+d  +++P+ai    +  +++ + +l+++ + +p   +  lnd      pf ++++++ + +  + ++a+il
   EEA19151.1 254 SVMIGQISAIYASLSSDATAHMSEEVQDAGRNVPIAIAWGYFSNGLMAIVLLIAYLFAIPSVEDA-LNDNTGF--PFLYVFQNAVSEAGLNGLTAIIL 348
                  8999999999999999***************************9999999999999999987744.4444444..7********************** PP

  AA_permease 298 taalssansslysasRvlyslakdglaP...kvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliilsylrfRk 392
                  + +++s + + +s+sR+ +++a+d+ +P   ++ k+ +kr+ P++ai+ls+iis+l+ l++  +l    +fn +++++ ++ + +++++i + + +Rk
   EEA19151.1 349 LPVIFSNIFFNASTSRQTFAFARDKGLPfskWISKVDTKRKIPVNAIALSCIISCLLSLINIGSLT---AFNAIISLNVAALMYTYIVSISCVI-YRK 442
                  ******************************88888889********************99887777...*******************999999.999 PP

  AA_permease 393 alkyqgrsieelgfkaallplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfli 461
                   +++++   ++  +  ++lp   i++++ +++ +    +   l+v  +  +w+++ f  +++i l++ +
   EEA19151.1 443 IWHAETLPPRRWDMGRWGLPV-NIIGVLYCCFAFFWSLWPSELPVTVDNFNWSVVIFGGVFIISLCMYV 510
                  988888877777777777765.45566666666666666667999999999999999999999998766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (529 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       970  (0.0541023); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.42
# Mc/sec: 3783.19
//
Query:       EEA19152.1  [L=354]
Description: hypothetical protein PMAA_014130 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (354 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       195  (0.0108762); expected 358.6 (0.02)
Passed bias filter:                      190  (0.0105974); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.23s 00:00:00.67 Elapsed: 00:00:00.39
# Mc/sec: 2725.08
//
Query:       EEA19153.1  [L=577]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.4e-13   49.1   0.5    0.00028   20.9   0.0    4.0  4  LysM      LysM domain


Domain annotation for each model (and alignments):
>> LysM  LysM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0      0.14   2.4e+03      31      43 ..     110     121 ..      95     122 .. 0.69
   2 !   20.9   0.0   1.6e-08   0.00028       1      44 []     227     271 ..     227     271 .. 0.93
   3 !    6.7   0.1   0.00042       7.5       1      43 [.     277     325 ..     277     326 .. 0.85
   4 !   16.8   0.0     3e-07    0.0053       1      38 [.     344     383 ..     344     385 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.14
                 SCGG--TTEEEEE CS
        LysM  31 spdkifpGqkLki 43 
                 ++  i +Gq+L +
  EEA19153.1 110 QTA-ISAGQELLW 121
                 345.999**9975 PP

  == domain 2  score: 20.9 bits;  conditional E-value: 1.6e-08
                 EEE-TT--HHHHHHHCTCHHHHHHHHCTCSSCG.G--TTEEEEEE CS
        LysM   1 YtVkkGDTLwsIAkrygitveklleaNnlsspd.kifpGqkLkiP 44 
                 YtV  ++T+  I+ +++++  +l+++N+l++    + +Gq L++P
  EEA19153.1 227 YTVMGNETCVNISTAHNVSTPALTALNGLDPGCnYLTAGQLLCLP 271
                 99999**********************99875568********98 PP

  == domain 3  score: 6.7 bits;  conditional E-value: 0.00042
                 EEE-TT--HHHHHHHC..TCHHHHHHHHC...TCSSCG.G--TTEEEEE CS
        LysM   1 YtVkkGDTLwsIAkry..gitveklleaN...nlsspd.kifpGqkLki 43 
                 Y V ++D++ sI +     ++  +++++N   n  +++    +Gq L+i
  EEA19153.1 277 YQVATNDSCTSIIGNLtrVVSTTTFQSWNpaiNYLCSNlYTMVGQYLCI 325
                 99****************566669******9988888844558998888 PP

  == domain 4  score: 16.8 bits;  conditional E-value: 3e-07
                 EEE-TT--HHHHHHHCTCHHHHHHHHC...TCSSCGG--TT CS
        LysM   1 YtVkkGDTLwsIAkrygitveklleaN...nlsspdkifpG 38 
                 Yt++ +DT+ ++A+ +gi+++++  +N   + +++  ++ G
  EEA19153.1 344 YTIQVNDTCQTVASTFGISEDDFYFLNpqlGTNCSS-LWLG 383
                 9**************************999999988.7665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (577 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       759  (0.0423336); expected 358.6 (0.02)
Passed bias filter:                      264  (0.0147247); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.64u 0.29s 00:00:00.93 Elapsed: 00:00:00.49
# Mc/sec: 3569.21
//
Query:       EEA19154.1  [L=1618]
Description: bacteriodes thetaiotaomicron symbiotic chitinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.2e-47  161.1   2.0    1.5e-46  159.6   1.9    1.8  1  Glyco_hydro_18   Glycosyl hydrolases family 18
    6.7e-11   42.5  17.0    6.7e-11   42.5  17.0    5.0  4  Chitin_bind_1    Chitin recognition protein
      2e-06   28.2   0.5    1.1e-05   25.8   0.2    2.4  2  DNase_NucA_NucB  Deoxyribonuclease NucA/NucB
  ------ inclusion threshold ------
      0.028   13.7   0.2       0.12   11.7   0.1    2.0  2  Glyco_hydro_114  Glycoside-hydrolase family GH114


Domain annotation for each model (and alignments):
>> Glyco_hydro_18  Glycosyl hydrolases family 18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  159.6   1.9   3.4e-50   1.5e-46      87     312 .]     146     391 ..     129     391 .. 0.89

  Alignments for each domain:
  == domain 1  score: 159.6 bits;  conditional E-value: 3.4e-50
                     HHHHHHHHHHHHHHHHCT-SEEEEEES-TTTS.....TCHHHHHHHHHHHHHHHHHHHHHHTSTTCEEEEEEESSHHHHHHHCHHHHHHHHT.SE CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xx RF
  Glyco_hydro_18  87 asrkkfadsvvsllrkygfDGiDidweypggn.....pedkenytallkelrealdkakategkkllLsaavpasasdlskgydlpkiakyl.Dy 175
                      + + fa+ v ++l++ygfDG+D+dweyp ++     ++d  ny+ l+++lr+ +d+     g+++ ++ ++p+s+++++ + d+p++ +   D+
      EEA19154.1 146 SDMAVFAEAVLKTLQQYGFDGVDLDWEYPAASdragkTADTVNYVYLVNQLRKTFDE----SGQTYGITFTIPTSYWYMQHF-DIPAMLEGGaDW 235
                     56788************************98899***999*************8884....489**************7777.9**9999999** PP

                     EEEETTTSSSTTSS.......BE--SS-SSBTCSSHHHHHHHHHHTT--GGGEEEEEESEEEEEEESSSSSS...............TSTTTEEE CS
                     xxxxxxxxxxxxxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...............xxxxxxxx RF
  Glyco_hydro_18 176 vnvmtYDfhgswdn.......vtghhaplydaslnvdeavkeylkagvpakklvlGvpfygrawalvsgadn...............tkeegvls 248
                      n+m+YD+hg wd        v+  h++l      ++++++ + +agv++ ++v+G+ fygr+++l + + +                +++g+ls
      EEA19154.1 236 ANLMAYDLHGVWDGkdpnigsVIASHTNL----TEIKASLDLLWRAGVNPTQIVMGMGFYGRSFTLSDYSCTepgcpfsgpgtagscSNSSGILS 326
                     **********8888777777789999999....6666666545599******************9977644478888888889999999****** PP

                     HHHHHHHHTEEEEEEEEETTTTEEEEEETT.EEEEE-SHHHHHHHHHHHHHTTESEEEEETGGGS CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18 249 ykelkellkkakakrkydskakapyvydge.efvsyDdpksikakadyvkakglgGvmiWsldqD 312
                     yke+ e +++++++  ++++a + y++ g+ +++s+D+++++++k+dy+ +  lgG+miW++dqD
      EEA19154.1 327 YKEITEIMDEEGSELIWNEEAAVNYLVWGGnQWISFDNAQTFQQKVDYANSVCLGGAMIWAVDQD 391
                     ***********************99955555********************************99 PP

>> Chitin_bind_1  Chitin recognition protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3  16.9       2.9   1.3e+04       9      38 .]      34      65 ..      26      65 .. 0.84
   2 !   42.5  17.0   1.5e-14   6.7e-11       1      38 []      70     110 ..      70     110 .. 0.92
   3 ?   -4.2   0.8         4   1.8e+04      11      18 ..     543     553 ..     538     555 .. 0.68
   4 ?   -6.7   7.9         4   1.8e+04       7      36 ..     592     623 ..     585     624 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 2.9
                   ---STT-EE-...TTSBEEBSHHHHSTT--BS- CS
  Chitin_bind_1  9 atCplnvCCS...qyGyCGttsdyCgagCqsnC 38
                     C + +CC    + G CG +s +C++ C snC
     EEA19154.1 34 SPCVNDACCQwkdNQGICGYGS-FCQTDCISNC 65
                   67*******644478****986.**999***** PP

  == domain 2  score: 42.5 bits;  conditional E-value: 1.5e-14
                    B-SGGC..TT---STT-EE-TTSBEEBSHHHHSTT--BS.- CS
  Chitin_bind_1   1 eCGkqa..ggatCplnvCCSqyGyCGttsdyCgagCqsn.C 38 
                    eCGk+a  + a+CplnvCCSq+G+CGt++ +Cg+gCq   C
     EEA19154.1  70 ECGKDAkdPSASCPLNVCCSQWGFCGTGDLFCGNGCQGDnC 110
                    7****96677***************************8667 PP

  == domain 3  score: -4.2 bits;  conditional E-value: 4
                    -...STT-EE- CS
  Chitin_bind_1  11 C...plnvCCS 18 
                    C   + ++CC 
     EEA19154.1 543 ClinQRSLCCN 553
                    65555678996 PP

  == domain 4  score: -6.7 bits;  conditional E-value: 4
                    TT---ST..T-EE.-TTSBEEBSHHHHSTT--B CS
  Chitin_bind_1   7 ggatCpl..nvCC.SqyGyCGttsdyCgagCqs 36 
                    +g+ Cp   + CC S   y   +  yC + C s
     EEA19154.1 592 EGEACPYlySFCCpSTDTYKNCEWHYC-DYCPS 623
                    567886533558868889999999999.67865 PP

>> DNase_NucA_NucB  Deoxyribonuclease NucA/NucB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0       3.1   1.4e+04      61      78 ..     166     184 ..     157     194 .. 0.70
   2 !   25.8   0.2   2.4e-09   1.1e-05      61      94 ..    1381    1414 ..    1368    1430 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 3.1
  DNase_NucA_NucB  61 gkdcD.EyPfAstkEggkk 78 
                      g d D EyP As + g + 
       EEA19154.1 166 GVDLDwEYPAASDRAGKTA 184
                      5566669**9998877664 PP

  == domain 2  score: 25.8 bits;  conditional E-value: 2.4e-09
  DNase_NucA_NucB   61 gkdcDEyPfAstkEggkkaslrcvdktdNqsaGg 94  
                       + +cDE+Pf +++Egg++a++ cv + +N  +G 
       EEA19154.1 1381 SLSCDEFPFNASEEGGTGAEVACVSAHQNDYQGT 1414
                       569*****************************97 PP

>> Glyco_hydro_114  Glycoside-hydrolase family GH114
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.1   2.7e-05      0.12      70     137 ..     130     190 ..     116     207 .. 0.73
   2 ?   -2.1   0.0      0.43   1.9e+03     152     185 ..    1295    1339 ..    1293    1378 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 2.7e-05
  Glyco_hydro_114  70 kldgWpgerwldirtaakrsskvrsimkaridlaaakGfdgvepDnvDsyesndtgflltaadqlayv 137
                       ++ W + r  d +    r s+++ + +a+++ +++ Gfdgv++D+    +   +  + + ad+++yv
       EEA19154.1 130 YYESWSSGRACDAW----RPSDMAVFAEAVLKTLQQYGFDGVDLDWEYPAA---SDRAGKTADTVNYV 190
                      45677777777777....667888*********************844432...22344455566665 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.43
  Glyco_hydro_114  152 glknageliselvdafdfavnEeca...........eyseCdtye 185 
                       ++kn g++  + ++ ++f+ nE+             +y+eC + +
       EEA19154.1 1295 LQKNPGKIKGNGMELTYFSSNEQQKtggnrhdacsaKYKECVQEK 1339
                       688888888889999999999998888888888888778886654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1618 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       617  (0.0344135); expected 358.6 (0.02)
Passed bias filter:                      341  (0.0190195); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.89u 0.31s 00:00:01.20 Elapsed: 00:00:00.48
# Mc/sec: 10129.08
//
Query:       EEA19155.1  [L=274]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
      0.015   15.6   7.8      0.022   15.0   7.8    1.3  1  AJAP1_PANP_C    AJAP1/PANP C-terminus
      0.022   12.9   6.4       0.03   12.5   6.4    1.1  1  FSA_C           Fragile site-associated protein C-terminus
      0.033   14.1   4.4      0.044   13.7   4.4    1.1  1  PRR18           Proline-rich protein family 18
      0.095   11.5   0.2       0.13   11.1   0.2    1.1  1  Med12-LCEWAV    Eukaryotic Mediator 12 subunit domain
       0.87    9.6  30.1       0.49   10.4  27.6    1.7  2  Mucin           Mucin-like glycoprotein
        6.8    4.7  24.6        9.8    4.2  24.6    1.1  1  SSP160          Special lobe-specific silk protein SSP160
        8.3    4.2  11.9         11    3.8  11.9    1.1  1  Dicty_REP       Dictyostelium (Slime Mold) REP protein


Domain annotation for each model (and alignments):
>> AJAP1_PANP_C  AJAP1/PANP C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.0   7.8   8.5e-06     0.022      17      57 ..      48      88 ..      36     133 .. 0.64

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 8.5e-06
  AJAP1_PANP_C 17 ktvpnitlstkasrtttvatttstttrltqrtltvvttpep 57
                  + +p  ++st +++ttt++ttt+ttt++t++t+t+++ p +
    EEA19155.1 48 NGNPPEIQSTASTTTTTTTTTTTTTTTTTTTTTTTIQMPGT 88
                  33444444555554444444444444444444444444433 PP

>> FSA_C  Fragile site-associated protein C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   6.4   1.2e-05      0.03     573     628 ..      54     115 ..      35     130 .. 0.59

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.2e-05
       FSA_C 573 lndatsstiasaatasslsstkstvtivv....stndskdgaklgpdtatpsfd..lesfvr 628
                 +++++s+t+++++t++++++t +t+t+++     t    d  kl p    p ++  +e fv 
  EEA19155.1  54 IQSTASTTTTTTTTTTTTTTTTTTTTTTTiqmpGTTRFADDGKLNPSEWFPVYQrcIEHFVN 115
                 44443333333333333333222222222234667778888899999988887544777776 PP

>> PRR18  Proline-rich protein family 18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   4.4   1.7e-05     0.044      69     166 ..      52     153 ..      28     179 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.7e-05
       PRR18  69 rlaasgespa..agtsagtGataaGtsaGagarpddavrfsl..sltpeavlviqrrhlekqllarprrpfpspsadprrllapcprakaaglrrggat 163
                  +++s+ s +  ++t+++t +t++ t++ +  +   ++rf+   +l p   + + +r +e  +   + rp  +  a    +l pc ra + g   +   
  EEA19155.1  52 PEIQSTASTTttTTTTTTTTTTTTTTTTTTTIQMPGTTRFADdgKLNPSEWFPVYQRCIEHFVNVAQHRPTAQSLAAHINILLPCQRATTGGILNSSES 150
                 4444444444113444444455555666777888899***86337*****************************9999**********99666555554 PP

       PRR18 164 svp 166
                 s+ 
  EEA19155.1 151 SSR 153
                 443 PP

>> Med12-LCEWAV  Eukaryotic Mediator 12 subunit domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.2   4.9e-05      0.13      10      97 ..      29     140 ..      18     170 .. 0.66

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 4.9e-05
  Med12-LCEWAV  10 rrLaylc..akkLaqllnesaesqesnsssselssnessaksasstessastepvesa.......................lsellsCphhrdivla 81 
                   rrL ++   ++ L++  ne  +  e++s+ s++++++++++++++t+++++t+++++                        ++ +++ ++hr+ +  
    EEA19155.1  29 RRLRFVSapTRLLSHRHNENGNPPEIQSTASTTTTTTTTTTTTTTTTTTTTTTTIQMPgttrfaddgklnpsewfpvyqrcIEHFVNVAQHRPTAQS 125
                   44433321134455556655555556655555555555555555555555555555559999999999999***9999999**************** PP

  Med12-LCEWAV  82 LsailQvitleCPtaL 97 
                   L+a +  i+l C  a 
    EEA19155.1 126 LAAHIN-ILLPCQRAT 140
                   ***997.678887665 PP

>> Mucin  Mucin-like glycoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4  27.6   0.00019      0.49      59      94 ..      53      88 ..      42      97 .. 0.66
   2 ?   -1.6   0.0      0.94   2.4e+03      22      46 ..     136     160 ..     133     184 .. 0.56

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00019
       Mucin 59 tttttasttittkttkattttttttttttateaPsd 94
                 + +tastt+tt+tt++tttttttttttt+ + P +
  EEA19155.1 53 EIQSTASTTTTTTTTTTTTTTTTTTTTTTTIQMPGT 88
                445566666666666666666666666666666653 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.94
       Mucin  22 CvtangeGqsdaavveaaegqsklt 46 
                 C +a  +G  ++++ ++ ++qs+ +
  EEA19155.1 136 CQRATTGGILNSSESSSRQSQSQPE 160
                 6666666777766666666666543 PP

>> SSP160  Special lobe-specific silk protein SSP160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2  24.6    0.0038       9.8     670     701 ..      51      82 ..      35      92 .. 0.60

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.0038
      SSP160 670 pgsvpdeattttssttttttttttaapttttt 701
                 p  + + a+ttt++tttttttttt++ ttttt
  EEA19155.1  51 PPEIQSTASTTTTTTTTTTTTTTTTTTTTTTT 82 
                 55555555555555555555555555454444 PP

>> Dicty_REP  Dictyostelium (Slime Mold) REP protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8  11.9    0.0044        11     245     274 ..      52      81 ..      35     101 .. 0.53

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.0044
   Dicty_REP 245 ensqpskeknkttttttttttttsqartrk 274
                  ++q   ++++tttttttttttt++++t+ 
  EEA19155.1  52 PEIQSTASTTTTTTTTTTTTTTTTTTTTTT 81 
                 334444444444433333333333333332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (274 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       938  (0.0523175); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 1973.70
//
Query:       EEA19156.1  [L=124]
Description: hypothetical protein PMAA_014170 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (124 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1378  (0.0768587); expected 358.6 (0.02)
Passed bias filter:                      565  (0.0315132); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.37u 0.26s 00:00:00.63 Elapsed: 00:00:00.38
# Mc/sec: 972.25
//
Query:       EEA19157.1  [L=468]
Description: argininosuccinate lyase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-86  290.1   0.0    3.2e-86  289.6   0.0    1.2  1  Lyase_1   Lyase
    1.1e-23   83.7   0.0    7.5e-23   81.1   0.0    2.3  2  ASL_C2    Argininosuccinate lyase C-terminal


Domain annotation for each model (and alignments):
>> Lyase_1  Lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  289.6   0.0   3.5e-90   3.2e-86       1     312 []      15     310 ..      15     310 .. 0.99

  Alignments for each domain:
  == domain 1  score: 289.6 bits;  conditional E-value: 3.5e-90
                 CEEEEETCHHHHHHHHHHHHHGGGHHHHHCHHHHHHHHHHHTTSSTHHHHHHHHHHHHHHHCHCHHCGGHHHBSSSSSHHHHHHHHHHHHHHHHTTHSS CS
     Lyase_1   1 grftvkadklmgiftersrenfrlseedikalaalkkaaakanvdlkeeaaaiikaldevleegklddqfvlkviqegsgtavnmnlnevigellgekv 99 
                 grft   d+lm +++e+++++   +++di ++ a ++a    ++++ +e ++i+++ ++++ee++ +  fv+k ++e+++ta++++l e+ig      +
  EEA19157.1  15 GRFTEGLDPLMVQYNESLPYDRIFWKQDILGSLAFARANTRGGILTPTEFSEIERGFNQIAEEWSTN-SFVIKANDEDIHTANERRLGEIIG------K 106
                 899999*************************************************************.************************......8 PP

                 GIIIIITTT--HHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHTTT-EEEEEETTEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHTCEET CS
     Lyase_1 100 epndkvhtgqSsnDqvpTalrlalkkalsekLlpaleqLidalkekakefkdvvkiGrThlqdAtPvtlgqelsayaealerdrerlkellkrllvell 198
                 ++++k+htg+S+n+q++T++rl+l+++l  kL + l +Li++ +++a++  + +++G+Thlq+A+Pv++++++ ++a+a+ +++ rl+e+ kr+++++l
  EEA19157.1 107 DIAGKLHTGRSRNEQIATDMRLWLRDEL-RKLDSFLCDLIKVSVARAEQDIEYLMPGYTHLQKAQPVRWSHWVLSHAVAFASELGRLREVIKRVNKSPL 204
                 ****************************.66******************************************************************** PP

                 TTTTTTSSTTTSCCTHHHHHHHHHHHHHCSTEESSSHHHHHHC-HHHHHHHHHHHHHHHHHHHHHHHHHHHTSTTTSSEEEEGCCTSSC-TTSTTTEBT CS
     Lyase_1 199 gggtavgtglnadpefaelvakelakvtglpvkapnsfeavsdrDavvellgalkllatsLskfaeDlrllssgeaglvelslaesepGSSiMPgKvNP 297
                 g g+++g+++ +d+e   ++akel+ ++g   ++ ns++ v+drD+ +e++++ + +++++s++aeDl+++ss e+g+v l +a+s+ GSS+MP+K+N 
  EEA19157.1 205 GTGALAGNPFHIDRE---AMAKELG-FDG---ITINSMNTVADRDFAMETMQWGSSFMLKISRWAEDLIIYSSLEFGFVRLADAYST-GSSLMPQKKNA 295
                 ***************...*******.***...*******************************************************.*********** PP

                 HHHHHHHHHHHHHHH CS
     Lyase_1 298 vqlElltgvagrvvG 312
                 ++lEll+g+agr++G
  EEA19157.1 296 DSLELLRGKAGRAFG 310
                 ************998 PP

>> ASL_C2  Argininosuccinate lyase C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0      0.43   3.9e+03      17      36 ..     171     190 ..     167     197 .. 0.81
   2 !   81.1   0.0   8.4e-27   7.5e-23       2      69 .]     373     440 ..     373     440 .. 0.98

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.43
                 -HHHHHHHHHHHHHHHHHTT CS
      ASL_C2  17 pFReAHeivgravrlaeekg 36 
                 p R +H + ++av+ a e g
  EEA19157.1 171 PVRWSHWVLSHAVAFASELG 190
                 67889********9988766 PP

  == domain 2  score: 81.1 bits;  conditional E-value: 8.4e-27
                 TTHHHHHHHHHHCTS-HHHHHHHHHHHHHHHHHTT--GGG--HHHHHHH-TT--GGGGGGSSHHHHTT CS
      ASL_C2   2 stATdlADyLvrkGlpFReAHeivgravrlaeekgkeleeltleelkeisplleedveeaLdpeasVa 69 
                 ++AT+ ADyLvrkG+pFRe H+i+gr+v+lae++++++++ltle+l+ i++++ +dv+e+Ld+e++V+
  EEA19157.1 373 MLATEFADYLVRKGVPFREGHHISGRVVALAEKNNVPMDTLTLEQLQGIDSRFGPDVQECLDYERAVE 440
                 68***************************************************************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (468 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       364  (0.0203023); expected 358.6 (0.02)
Passed bias filter:                      357  (0.0199119); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 3045.21
//
Query:       EEA19158.1  [L=227]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (227 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       491  (0.0273858); expected 358.6 (0.02)
Passed bias filter:                      247  (0.0137766); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.47
# Mc/sec: 1450.11
//
Query:       EEA19159.1  [L=528]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.2e-20   72.4  46.8    2.1e-17   63.1  34.0    2.2  2  MFS_1     Major Facilitator Superfamily
    1.4e-09   37.4  19.5    9.8e-08   31.3   7.2    2.7  3  Sugar_tr  Sugar (and other) transporter
  ------ inclusion threshold ------
       0.26   11.6   0.1       0.26   11.6   0.1    4.1  4  COX7C     Cytochrome c oxidase subunit VIIc
        3.4    7.7   6.8        4.3    7.3   0.4    2.9  3  DUF2393   Protein of unknown function (DUF2393)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.1  34.0   4.8e-21   2.1e-17      12     271 ..      64     365 ..      55     400 .. 0.73
   2 !   10.8   9.8   3.8e-05      0.17      70     180 ..     389     500 ..     377     525 .. 0.76

  Alignments for each domain:
  == domain 1  score: 63.1 bits;  conditional E-value: 4.8e-21
       MFS_1  12 rsilgpalplalaedlgispse.........igllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfa..sslwlllvlrvlqGlg 98 
                 ++++g+a+p ++  +l+i+ ++         i    ++ ++g a + +++ +ls +fG+  v++++l++ +++ ++++l++   ++ + l++r +++++
  EEA19159.1  64 SMFVGFAAP-FV-GQLNIQQQAklyhkptiqITYFNSAASAGLATGGFIWWPLSHKFGHSAVIFWCLVGVLATqIWAPLMTrpDQYVPYLISRYFSAFF 160
                 222333333.33.33443333333333332266689999**********************************888888878455559*********** PP

       MFS_1  99 agalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee......... 188
                 + ++  +g  +++d+f   +rgra+ +l ++ ++Ga  gp ++g++a++  W+  ++ + +++++   lf ++++ e+++ ++++++  e         
  EEA19159.1 161 GVVVSILGPKYLTDMFFLHQRGRAFTVLHLALNFGASAGPTFSGFVAANSYWPIEYWWHVGLTAFT--LFPVFFFLEDTTYQPFKERSHEstaqsflsq 257
                 *****************************************************************9..7777777777777777777776688778766 PP

       MFS_1 189 ......kgtgpaplvp...........awkallkdpvlw.....illialllfffgfsg.lltllply......lqevlglsglllaglllallalvga 258
                       k                     +k ++++  l+     ++++++ +++f+f+  l +l+p++      ++  +g+s +  ++++  + +++++
  EEA19159.1 258 rfetffK--------GgrngqsiswgaMFKVFFRPFKLFmapviLIIAGFDTISFAFYVaLNALTPVWlqlpkkAHGIYGFS-VADNAAFTFVHWIGCI 347
                 6766663........133333333455666666666554443433555565666666666999999988888888999****.8999977777777777 PP

       MFS_1 259 ilallagrlsdr.....l 271
                 i+ + +  +sdr     +
  EEA19159.1 348 IGLIYGHMVSDRiplwfI 365
                 7777777777**444440 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 3.8e-05
       MFS_1  70 llfalglllllfa.sslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafv 166
                   ++lgl+ +++    +w +++++ +l  +g+ +++p+ + +i + f        + l s+   +G  +   + +++   +g ++v+ ++a+++++af+
  EEA19159.1 389 MPLGLGLVGIAMEyRLHWiVMAIGQLLVTIGSLVSIPVTVNYICECFRTHTTEATLILNSLRLWFGLSINFYVNPWID-KVGIEWVYGMMAFFCVFAFL 486
                 33444422233323447889*****************************8888888999999***************9.99****************99 PP

       MFS_1 167 lfllllpeepperk 180
                 + +ll++  ++ r+
  EEA19159.1 487 FLILLILFGHVIRE 500
                 76666644333333 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.3   7.2   2.2e-11   9.8e-08      40     275 ..      81     307 ..      55     341 .. 0.76
   2 ?    0.1   0.2     0.064   2.9e+02      10      72 ..     295     359 ..     286     361 .. 0.64
   3 !   12.0   2.9   1.6e-05     0.071      92     217 ..     395     522 ..     382     527 .. 0.78

  Alignments for each domain:
  == domain 1  score: 31.3 bits;  conditional E-value: 2.2e-11
                 HHHH.......HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SC CS
    Sugar_tr  40 skee....ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkk 134
                 ++++     +++++ + s++++G + G+++  +l+++fG   ++  + v +++ ++   + +   ++  ++++R ++ ++  ++s+l P y+  +   +
  EEA19159.1  81 QQAKlyhkPTIQITYFNSAASAGLATGGFIWWPLSHKFGHSAVIFWCLVGVLATQIWAPLMTRPDQYVPYLISRYFSAFFGVVVSILGPKYLTDMFFLH 179
                 222233336899**************************************************99*********************************** PP

                 CHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHH.HGGGS---HHHH.HHTT-HH.HHHHHHHHHHHCHHHHHHHHHHHHH CS
    Sugar_tr 135 lRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpalllli.lllflPESPryl.vekgkee.eakevlaklrgeedadrelaeekds 230
                  Rg+  ++  la+ fG   + +f  +++ +s+   w+i  +  + ++ + l+ +++fl+++  y  ++ + +e  a+ +l++         +++  ++ 
  EEA19159.1 180 QRGRAFTVLHLALNFGASAGPTFSGFVAANSY---WPIEYWWHVGLTAFTLFpVFFFLEDT-TYQpFKERSHEsTAQSFLSQ---------RFETFFKG 265
                 ********************************...***99988877766555166778887.66524444444344444444.........44444444 PP

                 HHHHHH.....HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHH CS
    Sugar_tr 231 leaeqeeekaswkellssktvrqrlligvvlqifqqltGinaimy 275
                  + +   +++sw+ +++ +    +l+++ v+ i+  + +i + +y
  EEA19159.1 266 GRNG---QSISWGAMFKVFFRPFKLFMAPVILIIAGFDTISFAFY 307
                 4444...33445555555433344566666666666555555555 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.064
                 HHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH.......HHHHHHHTHHHHHHHHHHHHHHHHHH CS
    Sugar_tr  10 llfgYdtgvigafltllkfaknfglsksksskee....ssvlsglivsiflvGaiiGslfagllgdr 72 
                 ++ g+dt   +++++l++      +  +k+        s  +  +++ +  +G+iiG +++ +++dr
  EEA19159.1 295 IIAGFDTISFAFYVALNALTPVWLQLPKKAH--GiygfSVADNAAFTFVHWIGCIIGLIYGHMVSDR 359
                 5566666666666666663322222222222..1346677778889999999*****9999999998 PP

  == domain 3  score: 12.0 bits;  conditional E-value: 1.6e-05
                 HHH-TTTT.SS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCC...HHHHHHHHH CS
    Sugar_tr  92 lqaaakgk.nsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglq...lvpalllli 186
                 l ++a ++  ++ v+++g++lv ig  +   ++  yi E   ++   a   l+ l + fG  + + ++  ++k++ ++ + ++ +++   +++ +ll++
  EEA19159.1 395 LVGIAMEYrLHWIVMAIGQLLVTIGSLVSIPVTVNYICECFRTHTTEATLILNSLRLWFGLSINFYVNPWIDKVGIEWVYGMMAFFCvfaFLFLILLIL 493
                 44445444478***************************************************************9977766665555111667777778 PP

                 HGGGS---HHHHHHTT-HHHHHHHHHHHHHC CS
    Sugar_tr 187 lllflPESPrylvekgkeeeakevlaklrge 217
                 ++++++E   +  +k   ee + vla+++ +
  EEA19159.1 494 FGHVIREATPFIESKS--EEGQHVLADGERT 522
                 8888999876665555..7777777775555 PP

>> COX7C  Cytochrome c oxidase subunit VIIc
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.1   5.8e-05      0.26      32      56 ..      50      74 ..      38      76 .. 0.85
   2 ?   -3.2   0.6       2.3     1e+04      44      55 ..     274     285 ..     272     287 .. 0.87
   3 ?    0.6   0.1      0.15   6.8e+02      31      51 ..     330     350 ..     330     352 .. 0.88
   4 ?   -5.7   2.8         4   1.8e+04      43      49 ..     479     485 ..     473     491 .. 0.44

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 5.8e-05
                --SSHHHHHHHHHHHHHHHHHHHHH CS
       COX7C 32 sknnKipfavkywgflgvgFalPFl 56
                + ++Ki+   ++++ ++vgFa+PF+
  EEA19159.1 50 PLSKKITVVSVLFLSMFVGFAAPFV 74
                4578999999**************8 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.3
                 HHHHHHHHHHHH CS
       COX7C  44 wgflgvgFalPF 55 
                 wg ++ +F+ PF
  EEA19159.1 274 WGAMFKVFFRPF 285
                 899999999999 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.15
                 S--SSHHHHHHHHHHHHHHHH CS
       COX7C  31 FsknnKipfavkywgflgvgF 51 
                 Fs+  +++f++++w+ +++g+
  EEA19159.1 330 FSVADNAAFTFVHWIGCIIGL 350
                 7888899********999997 PP

  == domain 4  score: -5.7 bits;  conditional E-value: 4
                 HHHHHHH CS
       COX7C  43 ywgflgv 49 
                 ++ ++++
  EEA19159.1 479 FFCVFAF 485
                 2222222 PP

>> DUF2393  Protein of unknown function (DUF2393)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   0.4   0.00096       4.3      14      44 ..      53      83 ..      51      99 .. 0.83
   2 ?   -3.5   0.1       2.1   9.5e+03       5      35 ..     394     423 ..     393     441 .. 0.61
   3 ?    2.9   0.2     0.022        98      19      41 ..     478     500 ..     471     513 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.00096
     DUF2393 14 rsavalfliflsllilflapfvvhliidkyl 44
                +++  ++++fls+++ f+apfv++l i+++ 
  EEA19159.1 53 KKITVVSVLFLSMFVGFAAPFVGQLNIQQQA 83
                55566899*******************9983 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 2.1
     DUF2393   5 lllglllkkrsavalfliflsllilflapfv 35 
                 +l+g+ +  r  + +++ + +ll+++ + + 
  EEA19159.1 394 GLVGIAMEYRLHW-IVMAIGQLLVTIGSLVS 423
                 5777777777776.66666677766655333 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.022
     DUF2393  19 lfliflsllilflapfvvhliid 41 
                  f+ ++++l+l+l++ ++h+i +
  EEA19159.1 478 AFFCVFAFLFLILLILFGHVIRE 500
                 56889999******9**999866 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (528 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       824  (0.0459591); expected 358.6 (0.02)
Passed bias filter:                      405  (0.0225891); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.43
# Mc/sec: 3719.07
//
Query:       EEA19160.1  [L=282]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-05   26.1   0.0    1.8e-05   25.3   0.0    1.4  1  Methyltransf_25  Methyltransferase domain
    0.00067   20.2   0.0     0.0012   19.4   0.0    1.4  1  Methyltransf_11  Methyltransferase domain
     0.0065   16.3   0.0     0.0087   15.9   0.0    1.2  1  Methyltransf_31  Methyltransferase domain


Domain annotation for each model (and alignments):
>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.3   0.0   3.1e-09   1.8e-05       2      95 ..      93     194 ..      92     195 .. 0.88

  Alignments for each domain:
  == domain 1  score: 25.3 bits;  conditional E-value: 3.1e-09
                      EEET-TTSHHHHHHHCTS.TSSEEEEEESSHHHHHHHHHHHHHTTT..TEEEEESBCCG.....BSSSTTTEEEEEEEST.GGGSSHHHHHHHH CS
  Methyltransf_25   2 LdlGcGtGrltlalakrl.gkakvtgvDiseemleaareraeeegl..nvefvqgdaed.....lpfedgsfDlvvssga.lhhlsdedlekal 86 
                      Ld+Gc   +++++l   + ++++++g++i++e++  a + +++e +    +f+ +d+ d     +++ +g+f +v++ g+ lh ++++d+ ka+
       EEA19160.1  93 LDVGCCFAQDVRKLVYDGaPAENLYGLEIQAEFISLAYRFFRDEAIlaPHHFIIADLMDranpeVQQVAGTFGIVHL-GMiLHTWDRADQLKAC 185
                      9**************997669********************9998899*********6643333457899*******.77699999999999** PP

                      HHHHHHEEE CS
  Methyltransf_25  87 keiarvLkp 95 
                      +++ ++L+ 
       EEA19160.1 186 QRVVELLRS 194
                      999999985 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.0     2e-07    0.0012       1      88 [.      93     189 ..      93     200 .. 0.84

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 2e-07
                      EEET-TTSHHHHHHHHTT...SEEEEEES-HHHHHHHHHHCCHHT-..EEEETTEECCC.....TSS-TT-EEEEEEES-CCC-CCHHHHHHHH CS
  Methyltransf_11   1 LdvGcGtGrlaealakrg...arvvgvDlskemlklakekaseegl..kvefvvadaek.....lpfednsfDlvvssevlhhvedpekalkei 84 
                      LdvGc+  + +++l   g   ++++g+++ +e++ la +  ++e +     f+ ad+ +     ++   ++f +v + + lh++ d+++ lk +
       EEA19160.1  93 LDVGCCFAQDVRKLVYDGapaENLYGLEIQAEFISLAYRFFRDEAIlaPHHFIIADLMDranpeVQQVAGTFGIVHLGMILHTW-DRADQLKAC 185
                      8**************777899****************999999988895579999999654444556668**************.577777777 PP

                      HHHE CS
  Methyltransf_11  85 aRvL 88 
                       Rv+
       EEA19160.1 186 QRVV 189
                      7776 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   1.5e-06    0.0087       2     114 ..      87     225 ..      86     267 .. 0.69

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 1.5e-06
  Methyltransf_31   2 dkglrvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielAre.naqklgldnveFeqgdieelekl.led..ekfDlilsnevl..nalad 89 
                      ++g r+lD+GC   +++ +l     p  +++G++i++e i+lA    +++  l   +F ++d  +  +  +++   +f +++   +l   + ad
       EEA19160.1  87 KDGQRFLDVGCCFAQDVRKLVYDGAPAENLYGLEIQAEFISLAYRfFRDEAILAPHHFIIADLMDRANPeVQQvaGTFGIVHLGMILhtWDRAD 180
                      68899****************66555666**************8834555566699******99955455777889999999988888844455 PP

  Methyltransf_31  90 pdkileei.ervlkpggilliedpr...................l 114
                      + k+ +++ e + ++ g+l++ ++                     
       EEA19160.1 181 QLKACQRVvELLRSEPGVLVVGQCVghidgvqspgragkfifkhN 225
                      555555550555556799999999866666666665555544442 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (282 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       486  (0.0271069); expected 358.6 (0.02)
Passed bias filter:                      451  (0.0251548); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.45u 0.28s 00:00:00.73 Elapsed: 00:00:00.47
# Mc/sec: 1792.98
//
Query:       EEA19161.1  [L=380]
Description: arsenite efflux transporter (ArsB), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.4e-54  182.2   6.1    8.4e-54  182.2   6.1    1.9  2  SBF             Sodium Bile acid symporter family
  ------ inclusion threshold ------
        3.5    8.0   5.3        2.4    8.5   0.1    2.7  2  FA_hydroxylase  Fatty acid hydroxylase superfamily


Domain annotation for each model (and alignments):
>> SBF  Sodium Bile acid symporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  182.2   6.1   9.4e-58   8.4e-54       1     194 [.      88     281 ..      88     282 .. 0.97
   2 ?   -2.4   0.3      0.36   3.3e+03      87     131 ..     345     350 ..     295     367 .. 0.63

  Alignments for each domain:
  == domain 1  score: 182.2 bits;  conditional E-value: 9.4e-58
         SBF   1 ailLilmmfpmglkveveklkellkr...pkalllglvlqwvikPllmfilakillrdlklepelavGlilvglapggamsnvwtylakGdlelsvvlv 96 
                 a++L++mm+p+++kv++e+l+ ++++    ++++++++++w+i P+ m +la+++l d    pel+ Glilvgla+++am+++wt la+Gd+e++++lv
  EEA19161.1  88 AVGLLVMMYPILCKVRYESLHHVFREreiWRQIAFSIFVNWIIAPFFMLGLAWAFLPDQ---PELREGLILVGLARCIAMVLIWTGLAGGDNEYCAILV 183
                 589***********************777789***********************9999...************************************* PP

         SBF  97 alstllailltPlllyllaksleqttlkvpieeivksvlivviiPliaGillryillkhkGrewfeskllpavspisligllltivvifalkgelive 194
                 a++++l+++l++ l+ ++++ + +  ++ ++++ +ksv ++++iPl a i++r  ++k++G  w+ +++++  sp+sligll+ti+v+fa++g ++v+
  EEA19161.1 184 AINSMLQMVLFAPLAVFFIAVISNDPIDFDYSTAAKSVAVFLGIPLGAAIITRFTIRKVAGPRWYDEVFVKWASPWSLIGLLFTILVLFASQGHQVVH 281
                 ***********888999999999999*********************************************************************997 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.36
         SBF  87 GdlelsvvlvalstllailltPlllyllaksleqttlkvpieeiv 131
                 ++++l                                       +
  EEA19161.1 345 SNQAL---------------------------------------A 350
                 33333.......................................3 PP

>> FA_hydroxylase  Fatty acid hydroxylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.1   0.00027       2.4      29      78 ..     104     159 ..      97     178 .. 0.68
   2 ?    0.6   0.5     0.074   6.7e+02      68      88 ..     277     297 ..     243     336 .. 0.52

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00027
  FA_hydroxylase  29 lHkvHHsseaptalaalrahpleallla.llll.llllllg...plsalll.vlvl 78 
                     + ++HH +++ + + + +++++  +++a +++l l++++l+   +l   l+ v ++
      EEA19161.1 104 YESLHHVFREREIWRQIAFSIFVNWIIApFFMLgLAWAFLPdqpELREGLIlVGLA 159
                     5579************************6444435556666654333333313333 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.074
  FA_hydroxylase  68 plsalllvlvlaallelliHs 88 
                     + ++  +v v++ +  l+++ 
      EEA19161.1 277 HQVVHQIVSVIRVAAPLIVYF 297
                     222222233333333333332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (380 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       854  (0.0476323); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.31s 00:00:00.88 Elapsed: 00:00:00.50
# Mc/sec: 2292.83
//
Query:       EEA19162.1  [L=135]
Description: arsenate reductase (ArsC), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      4e-21   75.9   0.0    5.4e-21   75.5   0.0    1.2  1  LMWPc     Low molecular weight phosphotyrosine protein phosph


Domain annotation for each model (and alignments):
>> LMWPc  Low molecular weight phosphotyrosine protein phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.5   0.0     3e-25   5.4e-21       2     141 ..       8     127 ..       7     128 .. 0.93

  Alignments for each domain:
  == domain 1  score: 75.5 bits;  conditional E-value: 3e-25
                 EEEESSSSSHHHHHHHHHHHHHHHTT-CCCEEEEEEESTSTTT-B--HHHHHHHHHTTS--TT-BB-BS-HHHHHHSSEEEESSHHHHHHHHHHCCTTG CS
       LMWPc   2 lfvClgNicRSpmAealfrkelekagleekvevdSaGtgalvgkradpravevlkekgislsghvarqlskeelaelDlilamdeenkreleslapeke 100
                 lfvC+ N++RS+mA a ++++      + ++ev+SaG+   ++++++p +ve++ e+gi++ +++++ l+ e ++  D+ ++m      +++++ p+k+
  EEA19162.1   8 LFVCIHNAGRSQMAAAYLNHLS-----GGAIEVRSAGSA--PANTVNPMVVEAMLEEGIDIRDQKPKILTPESVEASDVCITMGCG---DVCPFFPGKR 96 
                 8********************4.....4579********..******************************************644...669*****33 PP

                 GGGEEEGGGGSSTSS---HTTSSHHHHHHHHHHHHHHHHHH CS
       LMWPc 101 kakvkllgeyteqldieDPyygeieafeevldeieeavkkl 141
                          y  +++++DP++++iea + ++dei ++v+ l
  EEA19162.1  97 ---------Y-LDWKLDDPAGQGIEAIRPIRDEIRRRVEGL 127
                 .........4.689***********************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (135 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       287  (0.0160076); expected 358.6 (0.02)
Passed bias filter:                      268  (0.0149478); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.48
# Mc/sec: 853.33
//
Query:       EEA19163.1  [L=311]
Description: arsenic resistance protein ArsH [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.4e-23   80.8   0.0    1.2e-22   80.4   0.0    1.2  1  FMN_red   NADPH-dependent FMN reductase


Domain annotation for each model (and alignments):
>> FMN_red  NADPH-dependent FMN reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.4   0.0   6.5e-27   1.2e-22       2     151 ..     105     245 ..     104     249 .. 0.92

  Alignments for each domain:
  == domain 1  score: 80.4 bits;  conditional E-value: 6.5e-27
                 EEEEEES--STT-HHHHHHHHHHCCT-T.T-CEEEEETTTS.--..---HCHGHTCGGSHHHHHHHHHHHH-SCEEEEEEECTTCE-HHHHHHHHCHT- CS
     FMN_red   2 kilvisGSlrkgsntrklaewaaealkeagaevelidladlilpcalcdkdlesegqtsddvaellekiaaadaliivtPeYngsysgllKnalDrlsr 100
                 k+lv++GSlr++s+++ +a +a + l + g++v ++d  +l  p  + + d +   + +++v+el++  a++d+ ++v+Pe +g+ ++++Kn +D+++ 
  EEA19163.1 105 KVLVLYGSLRRRSYSKLVAYEASRILFRLGCDVRVFDPEGL--P--VKN-DVD---HGHEKVQELRALSAWSDGQLWVSPEQHGNLTAVFKNQIDWIPL 195
                 9*************************999***********5..6..333.554...379**************************************99 PP

                 ..SSCHCCTT-EEEEEEE-SSTTTTHHHHHHHHHHHHHTT-EEEECSEEEET CS
     FMN_red 101 .trgkkelrgKpvalvavgggrrgglraeeqlrqvlaelgaivvpraavavg 151
                  t + ++ +g+ +a++ v gg +++ +a+++lr + +++++ ++p+ + +++
  EEA19163.1 196 sTGSVRPTQGRTLAIAQVCGG-SQSFNAVNSLRILGRWMRMFTIPN-QSSIP 245
                 9999***************88.***********************9.76665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (311 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       435  (0.0242624); expected 358.6 (0.02)
Passed bias filter:                      396  (0.0220871); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 2082.99
//
Query:       EEA19164.1  [L=298]
Description: arsenic methyltransferase Cyt19, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.4e-29  101.6   0.0    5.8e-29  100.9   0.0    1.3  1  Methyltransf_31  Methyltransferase domain
    5.4e-21   75.1   0.0    9.3e-21   74.4   0.0    1.4  1  Methyltransf_25  Methyltransferase domain
    3.2e-20   72.6   0.0    5.9e-20   71.7   0.0    1.5  1  Methyltransf_11  Methyltransferase domain
    4.9e-15   55.5   0.0    2.1e-14   53.4   0.0    1.8  2  Ubie_methyltran  ubiE/COQ5 methyltransferase family
    1.4e-10   41.8   0.0    2.2e-10   41.1   0.0    1.3  1  Methyltransf_12  Methyltransferase domain
    1.8e-10   40.9   0.0    2.8e-10   40.3   0.0    1.3  1  Methyltransf_23  Methyltransferase domain
    1.5e-09   37.7   0.1    2.3e-09   37.1   0.1    1.2  1  PrmA             Ribosomal protein L11 methyltransferase (Prm
    2.3e-06   27.3   0.0    3.7e-06   26.6   0.0    1.3  1  MTS              Methyltransferase small domain
    2.7e-06   27.3   0.0    4.7e-06   26.5   0.0    1.4  1  PCMT             Protein-L-isoaspartate(D-aspartate) O-methyl
    6.6e-05   22.9   0.0     0.0001   22.2   0.0    1.2  1  Methyltransf_8   Hypothetical methyltransferase
    0.00019   20.8   0.0    0.00029   20.2   0.0    1.2  1  CMAS             Mycolic acid cyclopropane synthetase
    0.00034   20.4   0.0    0.00073   19.3   0.0    1.4  1  UPF0020          Putative RNA methylase family UPF0020
     0.0054   16.3   0.0     0.0097   15.5   0.0    1.4  1  DOT1             Histone methylation protein DOT1
  ------ inclusion threshold ------
      0.014   15.3   0.2      0.066   13.1   0.1    2.1  2  U71              Tegument protein UL11 homolog
      0.021   14.8   0.0      0.035   14.1   0.0    1.4  1  Methyltransf_32  Methyltransferase domain
       0.11   11.7   0.0          6    6.0   0.0    2.1  2  NNMT_PNMT_TEMT   NNMT/PNMT/TEMT family
       0.18   11.1   0.0        0.3   10.4   0.0    1.3  1  GidB             rRNA small subunit methyltransferase G


Domain annotation for each model (and alignments):
>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.9   0.0   5.5e-32   5.8e-29       3     150 ..      66     211 ..      64     217 .. 0.91

  Alignments for each domain:
  == domain 1  score: 100.9 bits;  conditional E-value: 5.5e-32
  Methyltransf_31   3 kglrvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielArenaqklgldnveFeqgdieeleklledekfDlilsnevlnaladpdkile. 95 
                      +g +v+DlG+G G ++f +a+++gp ++ +G+D++ ++i lA++na   gl+n +F +++i++++  l d+++D i+sn+v+n+++ +dk l  
       EEA19164.1  66 EGETVVDLGSGGGIDVFLAAHKVGPTGKATGVDMTRNMIDLATKNANASGLSNTSFIEASITSIP--LPDSSVDCIISNCVINLVPTKDKSLVf 157
                      6789*************************************************************..9**************998888776666 PP

  Methyltransf_31  96 .eiervlkpggilliedprllaelpakveeeskay.evvegakigtqkdelyellee 150
                       ei r+lkpgg+l+++d+ + +elp+++ +++++y +++ ga    q   ++e+l++
       EEA19164.1 158 hEIARLLKPGGRLAVSDILARKELPESIANDMTLYvGCIAGAS---QVVGYEEYLRQ 211
                      6********************************9999998887...55555555554 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.4   0.0   8.8e-24   9.3e-21       1      97 []      70     168 ..      70     168 .. 0.97

  Alignments for each domain:
  == domain 1  score: 74.4 bits;  conditional E-value: 8.8e-24
                      EEEET-TTSHHHHHHHCTST.SSEEEEEESSHHHHHHHHHHHHHTTT.TEEEEESBCCGBSSSTTTEEEEEEEST.GGGSSHHHHHHHHHHHHH CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlg.kakvtgvDiseemleaareraeeegl.nvefvqgdaedlpfedgsfDlvvssga.lhhlsdedlekalkeiar 91 
                      v+dlG G G +++ +a+++g  +k tgvD++ +m++ a ++a+++gl n +f++++++++p++d+s+D+++s+ + +++++ +d   +++eiar
       EEA19164.1  70 VVDLGSGGGIDVFLAAHKVGpTGKATGVDMTRNMIDLATKNANASGLsNTSFIEASITSIPLPDSSVDCIISN-CvINLVPTKDKSLVFHEIAR 162
                      89*****************669**************************************************6.55****************** PP

                      HEEEEE CS
  Methyltransf_25  92 vLkpgG 97 
                      +LkpgG
       EEA19164.1 163 LLKPGG 168
                      *****9 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.7   0.0   5.6e-23   5.9e-20       1      96 []      71     172 ..      71     172 .. 0.95

  Alignments for each domain:
  == domain 1  score: 71.7 bits;  conditional E-value: 5.6e-23
                      EEET-TTSHHHHHHH.HTT..SEEEEEES-HHHHHHHHHHCCHHT-.EEEETTEECCCTSS-TT-EEEEEEES-CCC-..CCHHHHHHHHHHHE CS
  Methyltransf_11   1 LdvGcGtGrlaeala.krg..arvvgvDlskemlklakekaseegl.kvefvvadaeklpfednsfDlvvssevlhhv..edpekalkeiaRvL 88 
                      +d+G+G+G+ +   a k g  ++ +gvD++ +m++la ++a+ +gl + +f++a+++++p++d+s+D+++s+ v++ v  +d + ++ eiaR+L
       EEA19164.1  71 VDLGSGGGIDVFLAAhKVGptGKATGVDMTRNMIDLATKNANASGLsNTSFIEASITSIPLPDSSVDCIISNCVINLVptKDKSLVFHEIARLL 164
                      59*******999999555599**************************99*****************************999************* PP

                      EEEEEEEE CS
  Methyltransf_11  89 kpgGllvi 96 
                      kpgG+l++
       EEA19164.1 165 KPGGRLAV 172
                      *****975 PP

>> Ubie_methyltran  ubiE/COQ5 methyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.4   0.0     2e-17   2.1e-14      43     153 ..      62     174 ..      57     199 .. 0.87
   2 ?   -0.6   0.0      0.67   7.1e+02     169     200 ..     236     267 ..     212     286 .. 0.73

  Alignments for each domain:
  == domain 1  score: 53.4 bits;  conditional E-value: 2e-17
                      --S--TTEEEEES-TT-HHHHHHHHHHHHHHEEEEEES-HHHHHHHHHHHHHHTSSTEEEEE--TTT-TTS-T-EEEEEEES-GGG-S..-HHH CS
  Ubie_methyltran  43 vavkrgakvlDvagGtgDlafklsdsvgekgkvvvlDinenmLkvgekklkeegkinieflqanaeeLpfeddsfDvvtvsfGlrnvt..Dklk 134
                       +vk+g++v+D+ +G g   f  +++vg +gk +++D+  nm++ + k ++ +g +n  f+ a+   +p  d s D++     +  v+  Dk+ 
       EEA19164.1  62 ANVKEGETVVDLGSGGGIDVFLAAHKVGPTGKATGVDMTRNMIDLATKNANASGLSNTSFIEASITSIPLPDSSVDCIISNCVINLVPtkDKSL 155
                      689**********999988899999****************************************************96555555455126666 PP

                      HHHHHHHHEEEEEEEEEEE CS
  Ubie_methyltran 135 aLkeayrvlkpGGrlvvle 153
                      +++e+ r lkpGGrl v +
       EEA19164.1 156 VFHEIARLLKPGGRLAVSD 174
                      779************9865 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.67
                      HHH.HHHHHHHHHHS-HHHHHHHHHHHHHS-- CS
  Ubie_methyltran 169 yskevlPvlGkllakdldsyryLvesirafPd 200
                      +s +++ v  k   + +++++yL++s    P 
       EEA19164.1 236 WSLDIFLVDTKANLNIYKEFSYLQQSTCCAPS 267
                      555555555566667899******99876665 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.1   0.0   2.1e-13   2.2e-10       1      99 []      71     170 ..      71     170 .. 0.89

  Alignments for each domain:
  == domain 1  score: 41.1 bits;  conditional E-value: 2.1e-13
  Methyltransf_12   1 LeiGcGtGsllrallekl.pdieytgvDispsaiedakeklakrennnnnnvelealdlldldggssfDlvvasnvlhhl..kdirevldnirk 91 
                      +++G+G G  ++  + k  p+ + tgvD  +++i+ a +  ++ +  n++++e   +++   d+  s+D +++++v++ +  kd+  v+++i++
       EEA19164.1  71 VDLGSGGGIDVFLAAHKVgPTGKATGVDMTRNMIDLATKNANASGLSNTSFIEASITSIPLPDS--SVDCIISNCVINLVptKDKSLVFHEIAR 162
                      589999998888888888****************888888888888888889998888876655..**************999999999***** PP

  Methyltransf_12  92 lLkpgGrl 99 
                      lLkpgGrl
       EEA19164.1 163 LLKPGGRL 170
                      ******97 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.3   0.0   2.6e-13   2.8e-10      21     132 ..      65     187 ..      38     219 .. 0.74

  Alignments for each domain:
  == domain 1  score: 40.3 bits;  conditional E-value: 2.6e-13
  Methyltransf_23  21 raggrvLdiGcGtGi.llevlrengf..svtgvDlspeaveiae...kakkaqkdqfdeqeaae...pqgkfdlIvlrevlehvp..dppellr 103
                      ++g  v+d+G G Gi +   + + g   + tgvD+ ++++++a    +a+   +++f e +++    p+ + d+I+++ v++ vp  d   +++
       EEA19164.1  65 KEGETVVDLGSGGGIdVFLAAHKVGPtgKATGVDMTRNMIDLATknaNASGLSNTSFIEASITSiplPDSSVDCIISNCVINLVPtkDKSLVFH 158
                      67789*********625666677788899*************9776644444444443333333666999***************9999***** PP

  Methyltransf_23 104 qiatllkpgGylllseplaslkedrllld 132
                       ia+llkpgG+l +s++la+ +  +++ +
       EEA19164.1 159 EIARLLKPGGRLAVSDILARKELPESIAN 187
                      *****************999866666443 PP

>> PrmA  Ribosomal protein L11 methyltransferase (PrmA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.1   0.1   2.1e-12   2.3e-09     159     266 ..      64     180 ..      44     191 .. 0.82

  Alignments for each domain:
  == domain 1  score: 37.1 bits;  conditional E-value: 2.1e-12
        PrmA 159 vkegeevlDvGtGSGi.LaiaaakLgak.kvvavDiDevAvkvakeNaelNkveaklevals.eellk.eekadvivaNILaevl.....ielaedikk 248
                 vkege+v+D+G G Gi   +aa+k+g   k+++vD+    ++ a +Na+  ++++   + +s  +++  ++++d i++N + + +          +i++
  EEA19164.1  64 VKEGETVVDLGSGGGIdVFLAAHKVGPTgKATGVDMTRNMIDLATKNANASGLSNTSFIEASiTSIPLpDSSVDCIISNCVINLVptkdkSLVFHEIAR 162
                 899*************6679******6439***********************9955454331333324699********9999944442246789*** PP

        PrmA 249 lvkeggllilSGilkeka 266
                 l+k+gg+l++S il++k+
  EEA19164.1 163 LLKPGGRLAVSDILARKE 180
                 **************9986 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.6   0.0   3.5e-09   3.7e-06      31     137 ..      66     172 ..      59     191 .. 0.83

  Alignments for each domain:
  == domain 1  score: 26.6 bits;  conditional E-value: 3.5e-09
                 TCSEEEEET-TTSH.HHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTT.TSTTS-EEEEEE---STTTCHCHHHHHHHHHHHHH CS
         MTS  31 lsgkvlDlGcGaGv.lgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvle.eveekkfdlivsNPPfhagkatelavaeeliaeAk 126
                 + ++v+DlG+G G+ + +a+ k  p+ + t vd   + +++a++n++a++l+ +++++ ++++  +++ ++d+i+sN  +     +++++   +++e +
  EEA19164.1  66 EGETVVDLGSGGGIdVFLAAHKVGPTGKATGVDMTRNMIDLATKNANASGLSnTSFIEASITSiPLPDSSVDCIISNCVINLVPTKDKSL---VFHEIA 161
                 5678*******99856677778899999************************9999999988835679*********9988776655554...467778 PP

                 HHEEEEEEEEE CS
         MTS 127 eaLkegGeLli 137
                 + Lk+gG+L +
  EEA19164.1 162 RLLKPGGRLAV 172
                 89999999875 PP

>> PCMT  Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.5   0.0   4.5e-09   4.7e-06      67     132 ..      60     125 ..      51     173 .. 0.81

  Alignments for each domain:
  == domain 1  score: 26.5 bits;  conditional E-value: 4.5e-09
                 HHTT--TT-EEEEES-TTSHHHHHHHHHHCTTCEEEEEESBHHHHHHHHHHHHHCTTCSEEEEES- CS
        PCMT  67 ellelkkgarvLevGsGsGyltavlarlvgekgrvvsierikelveeakrnlkkldlenvivvvgD 132
                  + ++k+g+ v+++GsG G+   + a+ vg++g++ +++ ++++++ a++n ++++l+n +++++ 
  EEA19164.1  60 AYANVKEGETVVDLGSGGGIDVFLAAHKVGPTGKATGVDMTRNMIDLATKNANASGLSNTSFIEAS 125
                 57789******************************************************9998875 PP

>> Methyltransf_8  Hypothetical methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.2   0.0   9.9e-08    0.0001     107     167 ..     120     183 ..     104     194 .. 0.80

  Alignments for each domain:
  == domain 1  score: 22.2 bits;  conditional E-value: 9.9e-08
                     TEEES-TTS-S--TT-EEEEE..EES---SS-HHH.HHHHHHHHEEEEEEEEEEEEGGG-S-HH CS
  Methyltransf_8 107 rvvacdlakvPledesvdvav..fclslmgtnlad.flkeanrvlkvGGllkvaevksrfesvk 167
                       +   ++ +Pl d+svd ++  + + l+ t+ ++   +e+ r+lk+GG l v+++ +r e  +
      EEA19164.1 120 SFIEASITSIPLPDSSVDCIIsnCVINLVPTKDKSlVFHEIARLLKPGGRLAVSDILARKELPE 183
                     556778999*********887535578887766551679*****************99976555 PP

>> CMAS  Mycolic acid cyclopropane synthetase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.0   2.7e-07   0.00029      58     172 ..      62     180 ..      56     196 .. 0.87

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 2.7e-07
                 TT--TT-EEEEES-TTSHHHHHHHHHH-..-EEEEEES-HHHHHHHHHHHHTS-SSS-EEEEES.-GGG---.--SEEEEES-GGGTSGGGHHHHHHHH CS
        CMAS  58 lelkpGmtlLdiGcGWGslvrraveryd..vkvvglTlSkeqaklakkrvdeldlerkvevkll.dyedlde.kvdrvvsvgafehvgkenydtffkkl 152
                 +++k+G+t++d+G G G  v  a+++ +   k  g+ + ++   la k+ ++ +l+++  ++ +     l++  vd ++s  +++ v ++     f+++
  EEA19164.1  62 ANVKEGETVVDLGSGGGIDVFLAAHKVGptGKATGVDMTRNMIDLATKNANASGLSNTSFIEASiTSIPLPDsSVDCIISNCVINLVPTKDKSLVFHEI 160
                 689**********************99733589**********************999888754133455556************************** PP

                 HHHS-TT-EEEEEEEEE--H CS
        CMAS 153 kkllkedGllllhtitslhk 172
                  +llk++G+l++  i ++++
  EEA19164.1 161 ARLLKPGGRLAVSDILARKE 180
                 ***********999988765 PP

>> UPF0020  Putative RNA methylase family UPF0020
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.0   6.9e-07   0.00073      77     128 ..      92     142 ..      82     143 .. 0.87

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 6.9e-07
                 --EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EEEE- CS
     UPF0020  77 lklygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvivtn 128
                  k  g+D+ r++++ a +Na++ g++++  f +a +++++l++++vd i++n
  EEA19164.1  92 GKATGVDMTRNMIDLATKNANASGLSNTS-FIEASITSIPLPDSSVDCIISN 142
                 5679*********************9886.55569****************9 PP

>> DOT1  Histone methylation protein DOT1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   9.2e-06    0.0097      38      87 ..      62     112 ..      57     121 .. 0.89

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 9.2e-06
                 TT--TT-EEEEES-TTSHHHHHHHHHH-.-SEEEEEE--HHHHHHHHHHHH CS
        DOT1  38 vnlkkedvFvDLGSGvGnvvlqaalevg.cklsvGvEimdnaselaekqke 87 
                  n+k+ ++ vDLGSG G  v++aa +vg + +++Gv+++ n  +la k+++
  EEA19164.1  62 ANVKEGETVVDLGSGGGIDVFLAAHKVGpTGKATGVDMTRNMIDLATKNAN 112
                 58999*********************9846689*************99865 PP

>> U71  Tegument protein UL11 homolog
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0         3   3.2e+03       2      17 ..      52      67 ..      51      73 .. 0.62
   2 ?   13.1   0.1   6.3e-05     0.066       4      25 ..     262     283 ..     260     285 .. 0.93

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 3
         U71  2 GakCCkPvsCGmCkkt 17
                G  C  Pv+    k  
  EEA19164.1 52 GLSCGNPVAYANVKEG 67
                5567777776666555 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 6.3e-05
         U71   4 kCCkPvsCGmCkktentlidyk 25 
                  CC P sC    kte + idy 
  EEA19164.1 262 TCCAPSSCSEQAKTESAEIDYN 283
                 6********************5 PP

>> Methyltransf_32  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   3.4e-05     0.035      24      95 ..      65     132 ..      55     179 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 3.4e-05
  Methyltransf_32  24 sgaltvvDvGaGkgYLsfvlalkekeyklkvvgidakeelvekaekraeklgkkfnkrlsfaelsieeatss 95 
                      ++ +tvvD+G+G g   f  a+ ++    k +g+d+ +++++ a k a++ g  + +++sf+e+si+++  +
       EEA19164.1  65 KEGETVVDLGSGGGIDVFLAAH-KVGPTGKATGVDMTRNMIDLATKNANASG--L-SNTSFIEASITSIPLP 132
                      6779********9966665555.88899************************..7.99******99987665 PP

>> NNMT_PNMT_TEMT  NNMT/PNMT/TEMT family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0     0.034        36      55      76 ..      65      86 ..      53      90 .. 0.85
   2 ?    6.0   0.0    0.0057         6     159     204 ..     136     179 ..     118     184 .. 0.70

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.034
                    S-ECEEEEET-TT--GGGTTGG CS
  NNMT_PNMT_TEMT 55 kkgdtllDiGaGPTvyqllsar 76
                    k+g+t++D+G+G  + + l+a 
      EEA19164.1 65 KEGETVVDLGSGGGIDVFLAAH 86
                    679*********9998888875 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.0057
                     EEEEEEESSHHHH-SSHHHHHHHHHHHHTTEEEEEEEEEEEECS-S CS
  NNMT_PNMT_TEMT 159 advvvtifcleaacedleeylralrnlasllkpGGhlvlggvlees 204
                     +d++++   ++ + ++ ++     +++a+llkpGG+l + ++l  +
      EEA19164.1 136 VDCIISNCVINLVPTKDKS--LVFHEIARLLKPGGRLAVSDILARK 179
                     5666666555555444333..246899*************999876 PP

>> GidB  rRNA small subunit methyltransferase G
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   0.00028       0.3      45     131 ..      64     151 ..      57     181 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00028
                 S-CCC-.EEEETSTTTTTHHHHHH..H-TTSEEEEEES-HHHHHHHHHHHHHCT-SSEEEEES-CCC.TTTTT-EEEEEEC-SSSHHHHH CS
        GidB  45 lkekrdkviDvGsGaGlPGipLai..arpelkltLleslekkiaFLeevkeelklenveivearaee.kqeeekydvvtsRAlaslnelt 131
                 +ke + +v+D+GsG+G+  + La   + p+ k t ++ +   i   ++  ++ +l+n+ ++ea + +   + +++d ++s  + +l   +
  EEA19164.1  64 VKEGE-TVVDLGSGGGID-VFLAAhkVGPTGKATGVDMTRNMIDLATKNANASGLSNTSFIEASITSiPLPDSSVDCIISNCVINLVPTK 151
                 55555.6*********95.6666523678999*********************************9988999999***999988876554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (298 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       436  (0.0243181); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              17  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 1936.98
//
Query:       EEA19165.1  [L=315]
Description: hypothetical protein PMAA_014260 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (315 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       412  (0.0229795); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2265.76
//
Query:       EEA19166.1  [L=658]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-09   36.4   0.0    2.6e-08   32.5   0.0    2.0  2  HSP70     Hsp70 protein
    3.1e-06   26.3   0.0      6e-05   22.0   0.0    2.2  1  MreB_Mbl  MreB/Mbl protein


Domain annotation for each model (and alignments):
>> HSP70  Hsp70 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    1.8   0.0    0.0061        54       2      30 ..      57      86 ..      56     107 .. 0.70
   2 !   32.5   0.0   2.9e-12   2.6e-08     136     370 ..     196     457 ..     176     461 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.0061
                EEEEEXSSEEEEEEEETTE.EEEEXXTTSX CS
       HSP70  2 iGiDLGttnsvvavmeggk.ievianeegn 30
                +G+D Gtt+s +a +  ++  +v+ n +  
  EEA19166.1 57 VGVDFGTTYSGFATWLTRSsEDVVPNRKWP 86
                8************99766515677776544 PP

  == domain 2  score: 32.5 bits;  conditional E-value: 2.9e-12
                 EEEEEXTTXXHHHHHHHHHHHHHTTXEE...EEE..EEHHHHHHHHHHTCCSS.........SCEEEEEEEEXSSXEEEEEEEEETTE.EEEEEEEE.. CS
       HSP70 136 avitvPaYfndaqRqatkdAgkiAGLnv...lRi..vNepTAaalaYGldkkd.........kernvlvyDlGggtfdvSilelekGv.fevkaTag.. 217
                  +++vPa + d  R  ++  ++ AG+ +    Ri  + ep Aaala     ++         ++ nv+v+D+Gggt d    ++++ + f+v    +  
  EEA19166.1 196 FILAVPAGWPDVSRCQIRYCAENAGFGSregDRIslISEPEAAALAMFHSFSSkleaggtfkENTNVMVVDMGGGTVDLITYTIKSLKpFRVAEACVgs 294
                 689**********************96522235444*********96433333467999998899**************99999976448997654411 PP

                 ETTXSHHHHHHHHHHHHHHHHHHHHSXXGGGSHHHHHHHHHHHHHHHHHTTTSSCSE...EEEEEEEEETTT.EEEEEEEEHHHHHHHHHHHHHHTHHH CS
       HSP70 218 DthlGGedfDealvehlveefkkkegidlskdkkalqrlkeaaekaKkeLSsskqte...inleietvdedg.kdlseklsRakfeelvedllertlep 312
                   + G    D++  + + e+f  k++    k     +   ++ e++K+ + + ++++   +++e+e+ +  +  d ++ l+ + + e+ ++++e+++  
  EEA19166.1 295 GAKCGSSTIDRHFQKLMEERFGGKYKNKSPKFIGPKSTFMNEFENVKRRFDNDTDSDtlpLDMELESSEYYDsDDGEVILKSEDLIEVFRPVVENVIGL 393
                 578999**************************9*****************88654432114556667766676899999******************** PP

                 HHHHHHHCTEE.GGGCSEEEEESGGGGSHHHHHHHHHHTT.CHHBSSS....HTTTHHHHHHHH CS
       HSP70 313 vekalkdaklk.keeidevvlvGGstRiPkvqelvkelfg.kepsktv....npDeavaiGAAv 370
                 +++  + ++ + ++ i +++l GG +    +q+++k++ +   p+++v     p  a+  GAA+
  EEA19166.1 394 IKEQAERTEAEnEHPITAIILCGGLAGSGYIQSQLKNFCQeTIPNTQVlippSPWSAICCGAAM 457
                 ******999994567***********************99666888875555577888888887 PP

>> MreB_Mbl  MreB/Mbl protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.0   0.0   6.6e-09     6e-05      88     320 ..     188     460 ..     165     466 .. 0.74

  Alignments for each domain:
  == domain 1  score: 22.0 bits;  conditional E-value: 6.6e-09
                 SS-SS--EEEEEE-SS--HHHHHHHHHHHHHTT.....-SEEEEEEHHHHHHHH..........TT--TTSSS-EEEEEE-SS-EEE...EEEETTEE. CS
    MreB_Mbl  88 kkslskprvvicvPsgiteverrAvkeaakkaG.....arevllieeplaAAiG..........aglpveepsgnmvvdiGggttev...avislggi. 167
                 +  l + + +++vP g  +v+r  ++  a++aG     ++++ li+ep aAA+           ag   +e +  mvvd+Gggt ++   ++ sl    
  EEA19166.1 188 TFELLSFHFILAVPAGWPDVSRCQIRYCAENAGfgsreGDRISLISEPEAAALAmfhsfsskleAGGTFKENTNVMVVDMGGGTVDLityTIKSLKPFr 286
                 3345677899*********************9966555678***********854444443333788899***************98333455655442 PP

                 ....EEEEEES-SHHHHHHHHHHHHHHHHS........EE--HHHH.....HHHHHHH-BSS--HHHH.EEEEEEEETTTTCEEEEEEEHHHHHHHHHH CS
    MreB_Mbl 168 ....vtsksvrvaGdeldeaiikyirkkyn........lliGerta.....ekikieigsavkeeeee.kmeikGrdlvtglpkevevsseevrealke 248
                      + +  + +  ++d +  k++ +++           iG +++     e++k +  + + +++    me++  +       ev ++se++ e+ + 
  EEA19166.1 287 vaeaCVGSGAKCGSSTIDRHFQKLMEERFGgkyknkspKFIGPKSTfmnefENVKRRFDNDTDSDTLPlDMELESSEYYDSDDGEVILKSEDLIEVFRP 385
                 1111333456888889999999999886642222222247887643333338999999988888887789***************************** PP

                 HHHHHHHHHHHHHHTS-HHHHHHHHHH-EEEESGGG...GSB.THHHHHHHHH.SS-EEE-SSTTTHHHHHHHHTTC CS
    MreB_Mbl 249 pvsaiveavkevLektppeLaadivdrgivltGGga...llk.gldkllseet.glpvkvaedpltcvakGtgkvle 320
                 +v++++  +ke  e+t +e    i+  +i+l+GG a    ++ +l+++ +e++ + +v +  +p ++++ G+++   
  EEA19166.1 386 VVENVIGLIKEQAERTEAENEHPIT--AIILCGGLAgsgYIQsQLKNFCQETIpNTQVLIPPSPWSAICCGAAMSNT 460
                 *******************999996..69999985522244315666666555467889999999999999887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (658 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       578  (0.0322383); expected 358.6 (0.02)
Passed bias filter:                      505  (0.0281667); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.26s 00:00:00.89 Elapsed: 00:00:00.41
# Mc/sec: 4765.20
//
Query:       EEA19167.1  [L=268]
Description: MSF1 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-25   89.0   0.0    2.3e-22   79.5   0.0    2.1  2  PRELI     PRELI-like family
  ------ inclusion threshold ------
       0.19   11.9   0.1       0.62   10.3   0.0    1.9  2  DUF3896   Protein of unknown function (DUF3896)


Domain annotation for each model (and alignments):
>> PRELI  PRELI-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.5   0.0   2.6e-26   2.3e-22       2     114 ..      16     137 ..      15     149 .. 0.85
   2 !    7.8   0.0    0.0003       2.7     112     155 ..     168     210 ..     150     212 .. 0.85

  Alignments for each domain:
  == domain 1  score: 79.5 bits;  conditional E-value: 2.6e-26
                 HHHHHHHT--SBTTBTTEEEEEEEEEEEET.TSEEEEEEEEEEEEESSTTSTTTSSS.......EEEEEEEEEEEEETTTTEEEEEEEESSSTTTEEEE CS
       PRELI   2 qVtaaflrryPnpiskhvisvdvlereldd.egklvteRlitlqvrvPrwlkkligv.......aktvyvleesvvdlkkrtlkletrNltfssllkve 92 
                 +V+ a++ ryPnp+skhv+++dv+er +d+ + +l+t+Rl  ++ ++P+ l kl+         + ++y+le++vvd k+  +k+e+rN++++ +l+v 
  EEA19167.1  16 AVSLAYFLRYPNPYSKHVLTSDVIERYVDPdTHRLHTTRLHLKKSKIPSTLLKLLPKgiggsenSGQSYILETTVVDAKEGWMKTESRNMEWTGILSVV 114
                 5889**************************5666*******************985444555545669******************************* PP

                 EEEEEEEETTTT...EEEEEEEE CS
       PRELI  93 ErvvYkphpens.ekTvlkqeak 114
                 E+  Y+ +   + ek  ++++++
  EEA19167.1 115 EKQHYEREMPPEgEKVNVRTTVT 137
                 *****987554445555555555 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0003
                 EEEEE..HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
       PRELI 112 eakisvkgslfglsskveklllkkfsenakkgkeglesvlkele 155
                 ++++s+ + ++g+++++e +++++  + + ++k+g++ vl+ l+
  EEA19167.1 168 RGIFSSLS-TAGIQRTIELIGVTRTRDAILRSKQGMNVVLERLR 210
                 56677766.9******************************9865 PP

>> DUF3896  Protein of unknown function (DUF3896)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0      0.68   6.1e+03       3       8 ..       8      13 ..       6      17 .. 0.80
   2 ?   10.3   0.0   6.9e-05      0.62      38      59 ..      98     121 ..      86     123 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.68
     DUF3896  3 htydyn 8 
                 tydy 
  EEA19167.1  8 STYDYS 13
                69**96 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 6.9e-05
     DUF3896  38 lkleidnyey..ilnlvemnhyer 59 
                 +k e  n e+  il +ve  hyer
  EEA19167.1  98 MKTESRNMEWtgILSVVEKQHYER 121
                 7888899887779**********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (268 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       396  (0.0220871); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.40u 0.22s 00:00:00.62 Elapsed: 00:00:00.37
# Mc/sec: 2166.72
//
Query:       EEA19168.1  [L=962]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
      0.026   14.6   0.0       0.51   10.4   0.0    2.6  2  Put_DNA-bind_N  Putative DNA-binding protein N-terminus


Domain annotation for each model (and alignments):
>> Put_DNA-bind_N  Putative DNA-binding protein N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   2.9e-05      0.51      16      48 ..     333     364 ..     331     364 .. 0.88
   2 ?    0.7   0.0     0.031   5.5e+02      12      36 ..     375     399 ..     374     407 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 2.9e-05
                     HHHHHHHTT--EE-HHHHHHHCTS-HHHHHHHH CS
  Put_DNA-bind_N  16 yLeelkeegveriSSteLaealgvtaaqvRKDL 48 
                     +Le+l+e + + i S+e+++ ++ +   +RKD+
      EEA19168.1 333 FLETLDEPE-QAIISQEISNICHYEYERIRKDF 364
                     678888775.78899*****************8 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.031
                     HHHHHHHHHHHTT--EE-HHHHHHH CS
  Put_DNA-bind_N  12 lYlryLeelkeegveriSSteLaea 36 
                      Y + L+++ ++g+ r+ S+ + ++
      EEA19168.1 375 KYFKRLSNVFDNGTPRVTSKAIPDR 399
                     69999999************99766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (962 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       793  (0.04423); expected 358.6 (0.02)
Passed bias filter:                      467  (0.0260472); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.74u 0.32s 00:00:01.06 Elapsed: 00:00:00.49
# Mc/sec: 5954.97
//
Query:       EEA19169.1  [L=293]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.8e-30  106.5   0.0    2.5e-30  106.0   0.0    1.1  1  Aminotran_4  Amino-transferase class IV


Domain annotation for each model (and alignments):
>> Aminotran_4  Amino-transferase class IV
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.0   0.0   1.4e-34   2.5e-30      12     219 ..      48     284 ..      41     286 .. 0.90

  Alignments for each domain:
  == domain 1  score: 106.0 bits;  conditional E-value: 1.4e-34
  Aminotran_4  12 eiff.ldeHleRLrksaellglelpfdeeelrkileelleannsen......grlrllvsrgggglgaatsepsvavyvsalppgpeseke......l 96 
                  ++++ l  H++RL ++a  +   +p +  +l++  ++++ea++ +       +rlr++v++ g +    +++p  a+ +++++++ +          +
   EEA19169.1  48 SPYYlLRFHQDRLLEAATHF--RWPKAVAFLQQPQDKFVEALDAFIpdhskaWRLRIMVDAEGKCE--VEVHPATAWPLRCMFLPTSFGELeslggsF 141
                  45555***************..***************************************99664..5666666666666666666555566777** PP

  Aminotran_4  97 plvtssdvrrdapsplpgaKtlnyldnvlarreakergad...evllvdedgnvtEgstsNvfivk......................ggelitPpls 169
                  p+++  d++ + ps++++ Kt++++++ +ar++   ++     evll++++g+v+Egs++ v+++                         e++tPpls
   EEA19169.1 142 PWRLVIDTTSTEPSQFTTYKTTSRDHYNAARKRVGITSRTdpvEVLLFNPEGEVMEGSITCVYFRTrphyqphhrhhhrrrnqeegkiWAEWVTPPLS 239
                  ***********************************99955567*******************77777******************99999******** PP

  Aminotran_4 170 sgiLpGitrrallelakalgleveereitlkdleeadeafltntlrgvlp 219
                  sg+  ++tr+++l +    g+ + e+ i++++l + + ++++n++rg +p
   EEA19169.1 240 SGGMVSVTRQYALYH----GF-CAEQVIRVDELVDGERCLISNGVRGYMP 284
                  ***************....99.*************************999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (293 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       353  (0.0196888); expected 358.6 (0.02)
Passed bias filter:                      309  (0.0172346); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 1960.45
//
Query:       EEA19170.1  [L=475]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.9e-14   52.3   5.1    2.7e-07   29.7   0.8    2.0  2  Fungal_trans_2  Fungal specific transcription factor domain
    9.7e-07   28.8  11.3    1.8e-06   27.9  11.3    1.4  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.7   0.8     3e-11   2.7e-07      36     145 ..     114     227 ..     102     283 .. 0.85
   2 !   24.8   0.2   9.9e-10   8.9e-06     243     354 ..     347     470 ..     297     472 .. 0.69

  Alignments for each domain:
  == domain 1  score: 29.7 bits;  conditional E-value: 3e-11
  Fungal_trans_2  36 kallhallalsafhl..qskgpkds.....lereakrykslalkelqealaelsstlsrnekykdiLaaiLllcsie.issgdvsdwrvhLeaat 122
                     k +  ++lalsa  +  +s+ ++++       ++ + y+++a++el e l+ +++  +     ++ La++++++++e  + g+ ++ ++hL++ +
      EEA19170.1 114 KLVTRMILALSASEMhkHSSINENYllgkcGTDDGLMYYTQAVQELLEDLSAPTQGDE----VDSKLATLIFMVHYElQFTGSIDRVQIHLRGFW 204
                     5666678888887773366666666**99988999999**************999999....9**************878899999********* PP

  Fungal_trans_2 123 sliksrggskasssslsskarfl 145
                     +l++++ + ++ + ++s+ +r l
      EEA19170.1 205 ALMSNHPIFEERHANHSQLNRRL 227
                     ********966666666655544 PP

  == domain 2  score: 24.8 bits;  conditional E-value: 9.9e-10
  Fungal_trans_2 243 sdlepdldeterassls.kdl..telfrlaaliylyrlv...lglpps.spevqelvkkllellellp..sspv.aiasLlWplFiaGceavded 327
                     + l++ +++++  ++   + +  + +f+ a ++++yr++   +++++s +++ +e+++kl+ ll++    +s++ +   ++W+ Fia++   d+ 
      EEA19170.1 347 DVLHIADEASKGRWTSNiEIItrFAAFYWANILFYYRMLkndPSFSTSqNELHKEAISKLIRLLHYRHkqDSDHrKRGRVVWCYFIAAIQTPDPV 441
                     33333344444443333333366999*************777666666455557899999999988887744445999***************** PP

  Fungal_trans_2 328 dRdfvrrrleele..qsrlgnvrrarqvl 354
                     +Rd++ ++l+++     +++  + + + +
      EEA19170.1 442 HRDWLIEKLADVRdmSVECKQLWSMAHTM 470
                     *********99986333447777666655 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.9  11.3     2e-10   1.8e-06       1      31 [.      11      41 ..      11      46 .. 0.91

  Alignments for each domain:
  == domain 1  score: 27.9 bits;  conditional E-value: 2e-10
                SS-HHHHHCT---STSSSS-HHHHHCTHHHC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCt 31
                ++C +Crk+K+KCd+ + +C++C+k+++ C+
  EEA19170.1 11 TGCLTCRKRKIKCDETRIKCKQCIKHRFSCE 41
                58*************6666***********8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (475 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       609  (0.0339673); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.40
# Mc/sec: 3547.72
//
Query:       EEA19171.1  [L=494]
Description: monoxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.8e-14   51.5   2.2    0.00019   20.8   0.0    3.3  3  FAD_binding_3   FAD binding domain
    4.1e-11   43.0   0.0    0.00018   21.2   0.0    2.2  2  DAO             FAD dependent oxidoreductase
    4.7e-10   39.2   0.2    0.00086   18.6   0.0    2.2  2  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    7.9e-07   28.5   0.3    1.4e-05   24.4   0.1    2.1  2  FAD_binding_2   FAD binding domain
    4.6e-06   26.8   0.1    3.9e-05   23.8   0.0    2.4  2  NAD_binding_8   NAD(P)-binding Rossmann-like domain
    3.4e-05   24.3   0.0      0.016   15.7   0.0    2.5  2  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
    7.2e-05   22.3   0.2    0.00024   20.6   0.2    1.7  1  FAD_oxidored    FAD dependent oxidoreductase
     0.0001   21.2   0.0      0.078   11.7   0.0    2.1  2  HI0933_like     HI0933-like protein
    0.00073   18.7   0.2       0.83    8.6   0.0    2.6  3  Lycopene_cycl   Lycopene cyclase protein
     0.0026   17.1   0.0     0.0087   15.3   0.0    1.8  2  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
      0.015   14.4   0.1       0.88    8.6   0.0    2.1  2  GIDA            Glucose inhibited division protein A
      0.023   14.7   0.3        2.4    8.1   0.0    2.4  2  NAD_binding_9   FAD-NAD(P)-binding
      0.063   12.1   0.0        7.2    5.3   0.0    2.3  2  Trp_halogenase  Tryptophan halogenase


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.2   3.2e-06    0.0044       4      35 ..      31      62 ..      29      67 .. 0.91
   2 !   12.3   0.0   5.1e-05     0.071     110     170 ..     146     203 ..     138     227 .. 0.86
   3 !   20.8   0.0   1.4e-07   0.00019     284     318 ..     338     372 ..     255     379 .. 0.88

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 3.2e-06
                   EEEE--SHHHHHHHHHHHHTTHHEEEEESSSS CS
  FAD_binding_3  4 VlIVGaGpaGlmlallLseaGvrvvlvekrst 35
                    lIVGaG  Gl++al+ +++G +v++ve+  t
     EEA19171.1 31 CLIVGAGVGGLTTALECRRKGHSVRVVERSPT 62
                   69***************************876 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 5.1e-05
                    HHHHHHHHHTEEETCSEEEECCEECCCCCCCEEEECCTTEEEEEEEEEEEE--GTT-HHHH CS
  FAD_binding_3 110 iLvehaeerglqvrfktevesleqdeegvtaevrdketgeeetvrakYlvGaDGgrStvrk 170
                    +L+++ +  g++v f+++v+  ++d ++ +a +  ++ ge+  ++a+ +++aDG  +++ k
     EEA19171.1 146 ALLAQVKGLGIEVTFGAKVTDYLEDADKQKAGIVLES-GER--IEADVVIAADGIGTKSHK 203
                    5667778899***********************9884.555..***********9887766 PP

  == domain 3  score: 20.8 bits;  conditional E-value: 1.4e-07
                    TTEEE-GGGTEEE-STTSHHHHHHHHHHHHHHHHH CS
  FAD_binding_3 284 grvflaGDAaHihpPtgGqGlNtaiqDavnLawkL 318
                    grv  +GD+aH+  P+ G G   a++Da+ La+ L
     EEA19171.1 338 GRVVQVGDSAHTFLPSSGSGATQAMEDAISLATCL 372
                    9******************************9877 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.0   1.3e-07   0.00018       3      34 ..      32      65 ..      30      90 .. 0.88
   2 !   19.8   0.0   3.6e-07    0.0005     144     206 ..     139     203 ..     135     248 .. 0.80

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 1.3e-07
                EEECTSHHHHHHHHHHHHTT..EEEEESSSSTTS CS
         DAO  3 viiGGGiiGlstAyeLarrg..Vtllekgdiags 34
                +i+G+G+ Gl+tA+e  r+g  V ++e+++ + s
  EEA19171.1 32 LIVGAGVGGLTTALECRRKGhsVRVVERSPTPNS 65
                8***************77789********88874 PP

  == domain 2  score: 19.8 bits;  conditional E-value: 3.6e-07
                 EHHHHHHHHHHHHHHTT-EEEESECEEE.EEEEETCEEEEEEECTEEEEEEEEEEE--GGGHH..H CS
         DAO 144 dpakltaalaraaealGveilegtevtg.leeedgkvwgverttpgendaadavVnaaGawsd..l 206
                 +  k++aal+++++ lG+e+ +g++vt+ le+ d++ +g+ + ++ge+ +ad v+ a G++++  +
  EEA19171.1 139 HRPKFVAALLAQVKGLGIEVTFGAKVTDyLEDADKQKAGI-VLESGERIEADVVIAADGIGTKshK 203
                 6789************************778888888888.5566877455889999999986432 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0   6.3e-07   0.00086       3      35 ..      31      62 ..      29      83 .. 0.85
   2 !   18.6   0.0   6.5e-07   0.00089     179     241 ..     137     201 ..     118     211 .. 0.85

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 6.3e-07
                 EEEE--SHHHHHHHHHHHHHTS-EEEEETTHCH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  3 vvviGgGpAGlaaaltlaqagakvtlvelegtc 35
                 ++++G+G++Gl++al+ +++g+ v +ve +  +
   EEA19171.1 31 CLIVGAGVGGLTTALECRRKGHSVRVVE-RSPT 62
                 78*************************5.3333 PP

  == domain 2  score: 18.6 bits;  conditional E-value: 6.5e-07
                  TTS-HHHHHHHHHHHHHTTEEEEESCEEEEEEETTEEEE..EEETTSCEEEESEEEE-S-EEES- CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 179 raldkelsaaleealekeGvevklgtsvkeidgngekle..vvledgeeidadlvvvavGvrpst 241
                  r + +++ aal ++++  G+ev +g++v++  ++ +k +   vle+ge+i+ad v+ a G+  ++
   EEA19171.1 137 RHHRPKFVAALLAQVKGLGIEVTFGAKVTDYLEDADKQKagIVLESGERIEADVVIAADGIGTKS 201
                  7888999999*********************9999955567*******************98776 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4   0.1     1e-08   1.4e-05       3      36 ..      32      65 ..      30      78 .. 0.89
   2 ?    2.1   0.0     0.061        84     141     204 ..     141     199 ..     131     213 .. 0.80

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 1e-08
                   EEE--SHHHHHHHHHHHHTTT-EEEEESSSGGGS CS
  FAD_binding_2  3 iViGsGlAGLaAAleaaeaGlkvavvekeqefgg 36
                   +++G+G++GL+ Ale++++G++v vve  +  ++
     EEA19171.1 32 LIVGAGVGGLTTALECRRKGHSVRVVERSPTPNS 65
                   8**************************9987665 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.061
                    HHHHHHHHHHHHTCTEEEEESEEEEEEEECTT.EEEEEEEEETTTTCEEEEEESEEEE-----GG CS
  FAD_binding_2 141 hallarlvesarkagvdfqerteadeLivedg.rvtGavvenpesgrevrirakavvlatgGfgr 204
                    ++ +a+l+++++ +g+++ + +++++ + + + +  G+v+e  +++r+++     vv+a+ G+g 
     EEA19171.1 141 PKFVAALLAQVKGLGIEVTFGAKVTDYLEDADkQKAGIVLE--SGERIEA----DVVIAADGIGT 199
                    67899********************9988755488888888..6666665....89999999996 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.0   2.9e-08   3.9e-05       1      30 [.      33      62 ..      33      83 .. 0.92
   2 ?   -0.4   0.0         1   1.4e+03      27      55 ..     193     223 ..     180     229 .. 0.80

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 2.9e-08
                   EE--SHHHHHHHHHHHCCTEEEEEE-SSSS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekrdr 30
                   IvGaG++Gl++A +++++g++v ++e+++ 
     EEA19171.1 33 IVGAGVGGLTTALECRRKGHSVRVVERSPT 62
                   9*************************9876 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 1
                    SSSSSSGGG-EECETT..CEECTS---EEET CS
  NAD_binding_8  27 krdrlGGraasyevpg..vrvdygahifhgs 55 
                    ++d++G +++   ++g  +++  g +if++s
     EEA19171.1 193 AADGIGTKSHKLVNGGddRAYSSGISIFRTS 223
                    6789999999999966679999******984 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   1.2e-05     0.016       3      35 ..      32      64 ..      30      69 .. 0.92
   2 ?    6.0   0.0     0.013        18      42      80 ..     143     182 ..     128     185 .. 0.86

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 1.2e-05
                EEECSSHHHHHHHHHHHHTTSEEEEEESSSSSS CS
   Pyr_redox  3 vvvGgGyiglElAgalaelgkkVtvversdkll 35
                ++vG+G+ gl  A + ++ g++V vvers+++ 
  EEA19171.1 32 LIVGAGVGGLTTALECRRKGHSVRVVERSPTPN 64
                8****************************9875 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.013
                 HHHHHHHHHHHTTEEEECSEEEEEEEEETTS.EEEEEEET CS
   Pyr_redox  42 askilqeklekngievllntkveeiegsedg.vesvklkd 80 
                 + ++l  +++ +giev +++kv+   +++d+   +++l++
  EEA19171.1 143 FVAALLAQVKGLGIEVTFGAKVTDYLEDADKqKAGIVLES 182
                 56778889999*******************9999999975 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.6   0.2   1.7e-07   0.00024       3     143 ..      32     195 ..      30     199 .. 0.71

  Alignments for each domain:
  == domain 1  score: 20.6 bits;  conditional E-value: 1.7e-07
  FAD_oxidored   3 vVvGGgpaGvaAAiaAaraGakvlLveergv..lGGlltsglvatdignkaee...............qvvtgiareflerlrq..rggarlkkrsk 80 
                   ++vG+g++G++ A+ + r+G +v +ve+++     G + s +++ + + ++ +                + ++i +e ++  +    g+  ++    
    EEA19171.1  32 LIVGAGVGGLTTALECRRKGHSVRVVERSPTpnSAGDFFSIGRNIVAHLYNYWpdlaaececinysgvIAYHKITGERISGPEPvpIGKPTMTL--- 125
                   8**************************7654116788888888888886655566888887765555555555555555555444333333332... PP

  FAD_oxidored  81 wn...........tfepevakavleemlaeagvtvllntrlveveke.gkriesvtveskegrktirAkvfiDAT 143
                    n           ++ p++++a+l ++ ++ g++v +++++++   + +k+  ++++es   +++i+A+v+i A 
    EEA19171.1 126 -NdgsekiipfsrHHRPKFVAALLAQV-KGLGIEVTFGAKVTDYLEDaDKQKAGIVLES---GERIEADVVIAAD 195
                   .13334567666677777777777775.6779*********999997567799999987...9999999999775 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.7   0.0   5.7e-05     0.078       3      34 ..      31      62 ..      29      69 .. 0.91
   2 !    7.4   0.0    0.0011       1.6     110     163 ..     142     196 ..     129     217 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 5.7e-05
                 EEEE--SHHHHHHHHHHHHTT--EEEE-SSSS CS
  HI0933_like  3 viviGgGaAGlmaAisaakrgkrVlllekakk 34
                  +++G+G  Gl +A++++++g++V ++e+ ++
   EEA19171.1 31 CLIVGAGVGGLTTALECRRKGHSVRVVERSPT 62
                 589*************************9875 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0011
                  HHHHHHHHHHHHHT-EEE-S--EEEEECETT.E.EEEEE.TTEEEEESEEEE--- CS
  HI0933_like 110 divdallkelkeagvklrletevksvekeed.gkfrvktkseeeleadklvlAtG 163
                  + v all+++k  g+++    +v++  +++d +k  + ++s+e++ead ++ A G
   EEA19171.1 142 KFVAALLAQVKGLGIEVTFGAKVTDYLEDADkQKAGIVLESGERIEADVVIAADG 196
                  56899*******************9966655055677779********9999866 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.3   0.0    0.0016       2.2       3      37 ..      32      64 ..      30      77 .. 0.90
   2 !    8.6   0.0    0.0006      0.83      82     146 ..     136     202 ..     122     226 .. 0.73
   3 ?   -2.7   0.0       1.7   2.3e+03     257     290 ..     339     372 ..     337     396 .. 0.77

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0016
  Lycopene_cycl  3 vviGaGpAglslAarlteakpglkvvlieaspsll 37
                   +++GaG  gl  A +    ++g +v ++e sp + 
     EEA19171.1 32 LIVGAGVGGLTTALEC--RRKGHSVRVVERSPTPN 64
                   79**************..9**********999875 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.0006
  Lycopene_cycl  82 grvsskrlkeellerlvengvk.lleakvesveeeea.geslvvleggrkirarlvvdarglaslkk 146
                     r ++ ++ + ll ++   g++    akv+   e+ +  +  +vle g++i+a +v+ a g++ +++
     EEA19171.1 136 SRHHRPKFVAALLAQVKGLGIEvTFGAKVTDYLEDADkQKAGIVLESGERIEADVVIAADGIGTKSH 202
                    555666666666666664443313468998888887768899*******************887763 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 1.7
  Lycopene_cycl 257 kvlaiGaaaglvhPaTGYsvarslaeapllasai 290
                    +v+++G  a  + P+ G    +++  a  la  +
     EEA19171.1 339 RVVQVGDSAHTFLPSSGSGATQAMEDAISLATCL 372
                    5889999999999999999999999998666544 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   6.3e-06    0.0087       1      33 [.      32      63 ..       9      78 .. 0.65
   2 ?   -1.9   0.0       1.1   1.6e+03     227     267 ..     156     197 ..     135     212 .. 0.52

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 6.3e-06
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEkgnig 33
                 +I+GaG  Gl++a+e++++g  ++ ++E+    
   EEA19171.1 32 LIVGAGVGGLTTALECRRKGH-SVRVVERSPTP 63
                 456666666666666666665.45566655444 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 1.1
  Pyr_redox_3 227 ikvlfnaevkeikeke..eeykvktedgkkvevkddvvlatGy 267
                  i+v f a+v++  e+   ++  +  e+g+++e+ d v++a G 
   EEA19171.1 156 IEVTFGAKVTDYLEDAdkQKAGIVLESGERIEA-DVVIAADGI 197
                  555555555554433200233333455544443.444544443 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.0   0.00063      0.88       2      29 ..      31      62 ..      30     108 .. 0.81
   2 ?    3.9   0.0     0.017        24     119     150 ..     166     197 ..     135     226 .. 0.76

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00063
                EEEE-SSHHHHHHHHHHHHTT--EEEE....E CS
        GIDA  2 viViGgGhAGceAAlaaarlGakvlLi....t 29
                + ++G+G  G+  Al++ r+G++v  +    t
  EEA19171.1 31 CLIVGAGVGGLTTALECRRKGHSVRVVerspT 62
                789*********************99855441 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.017
                 EEEEECTTEEEEEEETTS-EEEECEEEE--TT CS
        GIDA 119 eeliveekkvkgvvtedgetikakavviatGt 150
                 + l++ +k+ +g+v+e+ge i+a++v+ a G 
  EEA19171.1 166 DYLEDADKQKAGIVLESGERIEADVVIAADGI 197
                 34556669999****************99875 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.1     0.026        36       2      35 ..      33      61 ..      32      76 .. 0.80
   2 ?    8.1   0.0    0.0018       2.4     103     154 ..     143     196 ..     136     198 .. 0.76

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.026
  NAD_binding_9  2 ivGaGprGlavlerLlarakkkspleitlfdpse 35
                   ivGaG+ Gl+++ +  ++      +++ ++++s+
     EEA19171.1 33 IVGAGVGGLTTALECRRK-----GHSVRVVERSP 61
                   9**********9886555.....57777777765 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0018
  NAD_binding_9 103 lfeellarlpegvtvevh.raevvdleeradgq..avlladgaslaadaVvLAlG 154
                    ++++lla+++ g+ +ev   a+v+d  e+ad+q   ++l++g++++ad V+ A G
     EEA19171.1 143 FVAALLAQVK-GLGIEVTfGAKVTDYLEDADKQkaGIVLESGERIEADVVIAADG 196
                    5566666663.55666643889**9888888764569**************9977 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0     0.011        15       3      37 ..      32      63 ..      30      68 .. 0.89
   2 ?    5.3   0.0    0.0052       7.2     154     209 ..     141     197 ..     116     212 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.011
                    EEE--SHHHHHHHHHHHHHTTTSSEEEEEE-SSS- CS
  Trp_halogenase  3 vivGGGtaGwlaAaalakalkgklevtlveseeig 37
                    +ivG+G  G ++A  +++ +   ++v +ve + ++
      EEA19171.1 32 LIVGAGVGGLTTALECRRKG---HSVRVVERSPTP 63
                    7*****************99...899999987665 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0052
                     HHHHHHHHHHHHHCT-EEEE--EEEEEE-T.TS-EEEEEETTS-EEE-SEEEE-SGG CS
  Trp_halogenase 154 alyakfLrrvaearGvtrvegkvvevqlde.dgrveslrledgreveadlfiDcsGf 209
                      ++   L +  +  G++++ g  v+  l++ d + +++ le+g+++ead +i + G 
      EEA19171.1 141 PKFVAALLAQVKGLGIEVTFGAKVTDYLEDaDKQKAGIVLESGERIEADVVIAADGI 197
                     45566677778899***998877776666669999*****************88875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (494 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       441  (0.024597); expected 358.6 (0.02)
Passed bias filter:                      431  (0.0240393); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.42
# Mc/sec: 3525.28
//
Query:       EEA19172.1  [L=665]
Description: FHA domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.9e-13   49.2   0.1    9.8e-13   48.3   0.1    1.5  1  FHA           FHA domain
  ------ inclusion threshold ------
      0.019   15.3   0.0      0.051   13.9   0.0    1.7  1  Yop-YscD_cpl  Inner membrane component of T3SS, cytoplasmic d
       0.38   10.7   1.8       0.76    9.7   1.8    1.5  1  TAT_signal    TAT (twin-arginine translocation) pathway signa


Domain annotation for each model (and alignments):
>> FHA  FHA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.3   0.1   1.6e-16   9.8e-13       3      69 .]      60     136 ..      58     136 .. 0.80

  Alignments for each domain:
  == domain 1  score: 48.3 bits;  conditional E-value: 1.6e-16
                 EESS..........TTSSEETTSTTSTTTEEEEEEETTCEEEEEEEESSSSSEEETTEEESTTSEEEE-TTEEEEET CS
         FHA   3 iGRs..........sdcdivlddpsiSrkHalikfdkgsgkvyleDlgSknGtfvNgqrigkgepveLksgdvielG 69 
                 +GR+          s  +  +d++++Sr Ha+i ++ ++++vy++D gS +Gt +N+++i++++ + + sgdv+++G
  EEA19172.1  60 VGRAsksetknlvpSHDNGWFDSRVMSREHAVIGVKMEDKTVYVRDHGSLHGTQLNDVKITPKQNTTVTSGDVLTFG 136
                 5777554322222222333356899********9888889************************************8 PP

>> Yop-YscD_cpl  Inner membrane component of T3SS, cytoplasmic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   8.6e-06     0.051      36      83 ..      85     137 ..      80     139 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 8.6e-06
                   S-TT-EEEEEE..TTEEEEEE-CESS--EETTEE-S.ECC..--TTSEEEETT CS
  Yop-YscD_cpl  36 vsrkhlkLeve..eesvrledlgsrngllvngerve.ele..lrpgdvlelGt 83 
                   +sr+h+++ v+  ++ v ++d gs  g+ +n+ +++ +++  ++ gdvl+ G+
    EEA19172.1  85 MSREHAVIGVKmeDKTVYVRDHGSLHGTQLNDVKITpKQNttVTSGDVLTFGS 137
                   6999*998776448899*******************744468********995 PP

>> TAT_signal  TAT (twin-arginine translocation) pathway signal sequence
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   1.8   0.00013      0.76       6      24 ..     633     651 ..     633     652 .. 0.92

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00013
  TAT_signal   6 dFLKgsAAaaAAaalggca 24 
                 +F+K +A+aa +aa+g+ +
  EEA19172.1 633 TFMKYAAVAAIGAAVGSIG 651
                 7***************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (665 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1051  (0.0586201); expected 358.6 (0.02)
Passed bias filter:                      525  (0.0292822); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.73u 0.33s 00:00:01.06 Elapsed: 00:00:00.49
# Mc/sec: 4047.48
//
Query:       EEA19173.1  [L=624]
Description: mitochondrial outer membrane translocase receptor (TOM70), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.2e-37  126.1  26.3    4.3e-08   32.6   0.0   11.8 11  TPR_1        Tetratricopeptide repeat
    5.9e-37  122.8  26.3    9.3e-07   28.5   0.0   11.0 10  TPR_2        Tetratricopeptide repeat
    1.4e-24   86.5  10.8    1.6e-06   28.6   0.0    7.2  8  TPR_16       Tetratricopeptide repeat
      8e-22   75.6  19.0    4.3e-05   23.4   0.0   10.8 10  TPR_8        Tetratricopeptide repeat
    1.5e-20   72.0   9.3     0.0054   17.0   0.0    8.6  8  TPR_17       Tetratricopeptide repeat
    4.4e-20   71.1  24.4    9.4e-08   31.6   0.1    8.3  8  TPR_11       TPR repeat
    6.4e-16   58.4  27.4     0.0031   17.8   1.3    8.3  8  TPR_12       Tetratricopeptide repeat
    9.3e-15   54.5   7.9    7.8e-05   22.7   0.1    6.2  6  TPR_9        Tetratricopeptide repeat
    1.5e-14   54.3  20.7    0.00013   22.4   0.4    8.4  9  TPR_19       Tetratricopeptide repeat
    2.7e-13   49.5  16.6      0.037   14.8   0.0    9.7  9  TPR_14       Tetratricopeptide repeat
    3.9e-13   48.4  10.6      0.031   14.3   0.1    8.7  8  TPR_7        Tetratricopeptide repeat
    3.2e-10   40.1   7.2     0.0056   16.9   0.0    5.5  5  ANAPC3       Anaphase-promoting complex, cyclosome, subunit 3
    1.8e-05   24.4  20.3       0.76    9.7   0.2    8.8  9  TPR_10       Tetratricopeptide repeat
    6.3e-05   22.5   0.3    0.00051   19.5   0.6    3.4  4  TPR_MalT     MalT-like TPR region
    0.00012   21.5   7.9        1.8    8.1   0.1    6.2  6  SHNi-TPR     SHNi-TPR
     0.0033   17.3   3.2      0.051   13.4   0.3    3.0  3  IPPT         IPP transferase
     0.0052   15.7   1.3     0.0052   15.7   1.3    1.9  3  DUF2397      Protein of unknown function (DUF2397)
     0.0056   16.8  10.9       0.13   12.4   1.9    4.1  4  MAS20        MAS20 protein import receptor
     0.0076   16.5   4.7      0.018   15.3   4.7    1.6  1  AP3D1        AP-3 complex subunit delta-1
     0.0095   16.3   0.8      0.031   14.7   0.8    1.9  1  DUF2681      Protein of unknown function (DUF2681)
  ------ inclusion threshold ------
      0.022   14.9   0.2      0.048   13.8   0.2    1.5  1  TSGP1        Tick salivary peptide group 1
      0.026   15.1   3.1         28    5.7   0.2    4.8  3  TPR_4        Tetratricopeptide repeat
       0.11   12.5   0.6       0.21   11.6   0.6    1.3  1  DUF2561      Protein of unknown function (DUF2561)
       0.11   12.2   1.4         13    5.5   0.0    2.5  2  BCIP         p21-C-terminal region-binding protein
       0.81   10.4   7.7       0.11   13.1   2.0    2.6  1  U1snRNP70_N  U1 small nuclear ribonucleoprotein of 70kDa MW N
        0.9    9.6   9.3          4    7.5   0.0    5.1  6  DUF3856      Domain of Unknown Function (DUF3856)
        1.3    9.6   8.6        1.9    9.0   3.1    3.4  3  Usp          Universal stress protein family
        3.1    8.6   8.7         13    6.6   0.2    4.0  2  Sel1         Sel1 repeat
        6.9    5.5  26.8        9.9    4.9   0.1    4.9  5  NARP1        NMDA receptor-regulated protein 1
        8.7    7.2  32.8         40    5.1   0.7    9.2  9  TPR_6        Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.0   0.4    0.0011      0.63       8      33 ..     137     162 ..     133     163 .. 0.87
   2 ?    5.3   0.0     0.032        19       3      33 ..     165     195 ..     163     196 .. 0.90
   3 !   17.3   0.2   5.1e-06     0.003       2      25 ..     198     221 ..     197     228 .. 0.91
   4 !   10.2   0.4    0.0009      0.54      17      30 ..     312     325 ..     312     326 .. 0.97
   5 !    9.3   0.0    0.0017         1       3      33 ..     335     365 ..     333     366 .. 0.84
   6 ?    3.4   0.1      0.13        77      18      34 .]     387     403 ..     368     403 .. 0.79
   7 !   32.6   0.0   7.2e-11   4.3e-08       1      34 []     404     437 ..     404     437 .. 0.96
   8 ?    5.3   0.0     0.032        19       3      29 ..     440     466 ..     438     470 .. 0.88
   9 !   11.2   0.2   0.00042      0.25       2      31 ..     473     502 ..     472     504 .. 0.86
  10 !   13.0   0.0   0.00012      0.07      11      34 .]     523     546 ..     522     546 .. 0.90
  11 !   17.0   0.1   6.5e-06    0.0039       7      32 ..     553     578 ..     551     580 .. 0.92

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.0011
                 HHHHHHTT-HHHHHHHHHHHHHHSTT CS
       TPR_1   8 GnayfklgkydeAleyyekALelnPn 33 
                 Gn  +  ++y+ A+e y kA+   P+
  EEA19173.1 137 GNKAYGSKDYNRAIELYGKAILCKPD 162
                 66677889*************88887 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.032
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHSTT CS
       TPR_1   3 alynlGnayfklgkydeAleyyekALelnPn 33 
                  + n++++   l ++++ +e+ + AL  + +
  EEA19173.1 165 FYSNRAACWNVLSEWEKVVEDTSAALVMDSE 195
                 599*******************999988765 PP

  == domain 3  score: 17.3 bits;  conditional E-value: 5.1e-06
                 HHHHHHHHHHHHTT-HHHHHHHHH CS
       TPR_1   2 kalynlGnayfklgkydeAleyye 25 
                 kal++++ ay +l++yd Al ++ 
  EEA19173.1 198 KALNRRAIAYEHLEQYDNALLDFT 221
                 79******************9996 PP

  == domain 4  score: 10.2 bits;  conditional E-value: 0.0009
                 HHHHHHHHHHHHHH CS
       TPR_1  17 ydeAleyyekALel 30 
                 ydeA +++ekALel
  EEA19173.1 312 YDEAAQAFEKALEL 325
                 9************8 PP

  == domain 5  score: 9.3 bits;  conditional E-value: 0.0017
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHSTT CS
       TPR_1   3 alynlGnayfklgkydeAleyyekALelnPn 33 
                 al++++   +  g+ + Ale+ +k +e++P+
  EEA19173.1 335 ALNQRATFTYLRGDAQSALEDLNKSIEIQPS 365
                 6666777778899999**************7 PP

  == domain 6  score: 3.4 bits;  conditional E-value: 0.13
                 HHHHHHHHHHHHHSTTH CS
       TPR_1  18 deAleyyekALelnPnn 34 
                 d A++++e A+ +n ++
  EEA19173.1 387 DGAVDDFEAAIAHNKDD 403
                 66999******999875 PP

  == domain 7  score: 32.6 bits;  conditional E-value: 7.2e-11
                 HHHHHHHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1   1 akalynlGnayfklgkydeAleyyekALelnPnn 34 
                 ++++y +++++f lg++ eA ++y+k + l+P++
  EEA19173.1 404 PDIYYHRAQLHFILGEFAEAAKDYQKSIDLDPSF 437
                 589*****************************96 PP

  == domain 8  score: 5.3 bits;  conditional E-value: 0.032
                 HHHHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1   3 alynlGnayfklgkydeAleyyekALe 29 
                 ++ +lG++ +klg    A + +++ ++
  EEA19173.1 440 SHIQLGVTQYKLGSVASAMATFKRSVK 466
                 6899*******************9877 PP

  == domain 9  score: 11.2 bits;  conditional E-value: 0.00042
                 HHHHHHHHHHHHTT-HHHHHHHHHHHHHHS CS
       TPR_1   2 kalynlGnayfklgkydeAleyyekALeln 31 
                 ++++  G +++ +++y+ A+e ++kA+e +
  EEA19173.1 473 DVYNYYGELLLDQQDYQGAIEKFDKAVEME 502
                 566677999******************975 PP

  == domain 10  score: 13.0 bits;  conditional E-value: 0.00012
                 HHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1  11 yfklgkydeAleyyekALelnPnn 34 
                 ++ +++++eA+  ++kAL ++P++
  EEA19173.1 523 FQWKQDFKEAESLCQKALIIDPEC 546
                 66789*****************85 PP

  == domain 11  score: 17.0 bits;  conditional E-value: 6.5e-06
                 HHHHHHHTT-HHHHHHHHHHHHHHST CS
       TPR_1   7 lGnayfklgkydeAleyyekALelnP 32 
                 ++++++++gk  eAl+y+ +A el  
  EEA19173.1 553 MAQLLLQQGKVAEALKYFTRAAELAR 578
                 6999******************9975 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   0.4   0.00018      0.11       4      33 ..     133     162 ..     130     163 .. 0.88
   2 !   13.5   0.2   9.9e-05     0.059       2      28 ..     198     224 ..     197     228 .. 0.89
   3 !    9.8   0.8    0.0016      0.94      17      30 ..     312     325 ..     312     327 .. 0.95
   4 ?    7.1   0.0     0.011       6.8       4      33 ..     336     365 ..     333     366 .. 0.82
   5 ?    2.9   0.1      0.24   1.4e+02      18      34 .]     387     403 ..     368     403 .. 0.84
   6 !   28.5   0.0   1.6e-09   9.3e-07       1      33 [.     404     436 ..     404     437 .. 0.95
   7 ?    6.8   0.0     0.014       8.3       3      32 ..     440     469 ..     438     471 .. 0.90
   8 !   20.6   0.1   5.5e-07   0.00033       1      30 [.     472     501 ..     472     504 .. 0.93
   9 !   10.5   0.0   0.00091      0.55      14      33 ..     526     545 ..     522     546 .. 0.91
  10 !   19.6   0.1   1.1e-06   0.00064       7      32 ..     553     578 ..     549     580 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 0.00018
       TPR_2   4 lynlGlayyklgdyeeAleafekAleldPn 33 
                 l + G+ +y ++dy++A+e++ kA+   P+
  EEA19173.1 133 LKAAGNKAYGSKDYNRAIELYGKAILCKPD 162
                 5678999******************98886 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 9.9e-05
       TPR_2   2 ealynlGlayyklgdyeeAleafekAl 28 
                 +al++++ ay++l +y+ Al +f ++ 
  EEA19173.1 198 KALNRRAIAYEHLEQYDNALLDFTASC 224
                 69*******************998776 PP

  == domain 3  score: 9.8 bits;  conditional E-value: 0.0016
       TPR_2  17 yeeAleafekAlel 30 
                 y+eA++afekAlel
  EEA19173.1 312 YDEAAQAFEKALEL 325
                 9************8 PP

  == domain 4  score: 7.1 bits;  conditional E-value: 0.011
       TPR_2   4 lynlGlayyklgdyeeAleafekAleldPn 33 
                 l++++   y +gd + Ale+++k++e+ P 
  EEA19173.1 336 LNQRATFTYLRGDAQSALEDLNKSIEIQPS 365
                 55555566889****************995 PP

  == domain 5  score: 2.9 bits;  conditional E-value: 0.24
       TPR_2  18 eeAleafekAleldPnn 34 
                 + A+++fe+A++++ ++
  EEA19173.1 387 DGAVDDFEAAIAHNKDD 403
                 57999******999875 PP

  == domain 6  score: 28.5 bits;  conditional E-value: 1.6e-09
       TPR_2   1 aealynlGlayyklgdyeeAleafekAleldPn 33 
                 ++++y ++++++ lg+++eA+++++k++ ldP 
  EEA19173.1 404 PDIYYHRAQLHFILGEFAEAAKDYQKSIDLDPS 436
                 579*****************************6 PP

  == domain 7  score: 6.8 bits;  conditional E-value: 0.014
       TPR_2   3 alynlGlayyklgdyeeAleafekAleldP 32 
                  + +lG   yklg  + A + f+++++  +
  EEA19173.1 440 SHIQLGVTQYKLGSVASAMATFKRSVKKFE 469
                 6899********************999876 PP

  == domain 8  score: 20.6 bits;  conditional E-value: 5.5e-07
       TPR_2   1 aealynlGlayyklgdyeeAleafekAlel 30 
                 ++++++ G++++ ++dy+ A+e f+kA+e 
  EEA19173.1 472 PDVYNYYGELLLDQQDYQGAIEKFDKAVEM 501
                 579************************996 PP

  == domain 9  score: 10.5 bits;  conditional E-value: 0.00091
       TPR_2  14 lgdyeeAleafekAleldPn 33 
                 ++d++eA+ +++kAl +dP+
  EEA19173.1 526 KQDFKEAESLCQKALIIDPE 545
                 689****************8 PP

  == domain 10  score: 19.6 bits;  conditional E-value: 1.1e-06
       TPR_2   7 lGlayyklgdyeeAleafekAleldP 32 
                 ++++++++g+ +eAl++f +A el+ 
  EEA19173.1 553 MAQLLLQQGKVAEALKYFTRAAELAR 578
                 799********************986 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0      0.13        79       2      24 ..     135     157 ..     134     181 .. 0.74
   2 ?    4.0   0.1      0.13        79      22      57 ..     188     220 ..     183     228 .. 0.84
   3 !   12.1   0.2   0.00041      0.24      12      63 ..     311     362 ..     302     367 .. 0.81
   4 !   28.6   0.0   2.7e-09   1.6e-06      14      65 ..     387     435 ..     371     436 .. 0.86
   5 !   23.7   0.0   9.4e-08   5.6e-05       4      62 ..     445     500 ..     442     509 .. 0.90
   6 ?   -0.5   0.0       3.5   2.1e+03      48      65 ..     527     544 ..     520     547 .. 0.87
   7 !   13.7   0.5   0.00013     0.077      14      63 ..     530     576 ..     526     581 .. 0.58
   8 !   12.6   0.6   0.00027      0.16       3      27 ..     553     577 ..     552     589 .. 0.87

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.13
      TPR_16   2 alaraalragdyddAaaaleaal 24 
                 a+++ a+ ++dy +A++++  a+
  EEA19173.1 135 AAGNKAYGSKDYNRAIELYGKAI 157
                 578889*************5554 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.13
      TPR_16  22 aalkrdpssPdaaeAllllgdaalrqgrlaeAaaly 57 
                 aal +d   ++   Al+ ++ a+ ++  ++ A+  +
  EEA19173.1 188 AALVMD---SEYLKALNRRAIAYEHLEQYDNALLDF 220
                 677777...88999******************9444 PP

  == domain 3  score: 12.1 bits;  conditional E-value: 0.00041
      TPR_16  12 dyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraalra 63 
                  yd+Aa a+e al+++    +  +Al+ ++   + +g+ + A++ +++ ++ 
  EEA19173.1 311 GYDEAAQAFEKALELGELGEFEGDALNQRATFTYLRGDAQSALEDLNKSIEI 362
                 49**************999998888888888888888888888555555555 PP

  == domain 4  score: 28.6 bits;  conditional E-value: 2.7e-09
      TPR_16  14 ddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraalraap 65 
                 d A+  +eaa++ ++++Pd    +++++++++ +g++aeAa  y++ ++ +p
  EEA19173.1 387 DGAVDDFEAAIAHNKDDPD---IYYHRAQLHFILGEFAEAAKDYQKSIDLDP 435
                 7899**********77776...*******************99999999988 PP

  == domain 5  score: 23.7 bits;  conditional E-value: 9.4e-08
      TPR_16   4 araalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraalr 62 
                 +   +++g  + A a +++ +k++      ++ ++++g+++l q+++++A++ +++a++
  EEA19173.1 445 GVTQYKLGSVASAMATFKRSVKKF---ENVPDVYNYYGELLLDQQDYQGAIEKFDKAVE 500
                 5667999*****************...99999**********************99984 PP

  == domain 6  score: -0.5 bits;  conditional E-value: 3.5
      TPR_16  48 grlaeAaalyraalraap 65 
                 ++++eA+ l+++al  +p
  EEA19173.1 527 QDFKEAESLCQKALIIDP 544
                 5899********998877 PP

  == domain 7  score: 13.7 bits;  conditional E-value: 0.00013
      TPR_16  14 ddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraalra 63 
                  +A+ + + al  d   P++  A    ++++l+qg +aeA+ ++ +a++ 
  EEA19173.1 530 KEAESLCQKALIID---PECDIAVGTMAQLLLQQGKVAEALKYFTRAAEL 576
                 55555555666666...666666666666666666666666666666544 PP

  == domain 8  score: 12.6 bits;  conditional E-value: 0.00027
      TPR_16   3 laraalragdyddAaaaleaalkrd 27 
                 +a+++l++g+ ++A++++++a +++
  EEA19173.1 553 MAQLLLQQGKVAEALKYFTRAAELA 577
                 68999999*******9999999877 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.0     0.082        49      15      32 ..     144     161 ..     140     163 .. 0.83
   2 ?    5.3   0.1     0.046        28       2      24 ..     198     220 ..     197     227 .. 0.87
   3 ?    6.7   0.2     0.016       9.9      17      30 ..     312     325 ..     302     325 .. 0.93
   4 ?    5.9   0.0      0.03        18      15      33 ..     347     365 ..     334     366 .. 0.87
   5 ?    1.9   0.0      0.58   3.5e+02       2      17 ..     368     383 ..     367     398 .. 0.89
   6 !   23.4   0.0   7.1e-08   4.3e-05       2      33 ..     405     436 ..     404     437 .. 0.95
   7 ?    5.2   0.0     0.049        29       3      29 ..     440     466 ..     438     466 .. 0.90
   8 !    8.9   0.1    0.0032       1.9       3      33 ..     474     504 ..     472     505 .. 0.89
   9 ?    4.5   0.0     0.082        49      14      34 .]     526     546 ..     522     546 .. 0.91
  10 !   12.3   0.0   0.00027      0.16       7      32 ..     553     578 ..     549     580 .. 0.92

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.082
                 T-HHHHHHHHHHHHHHHH CS
       TPR_8  15 gdyeeAkeyyekaleldp 32 
                 +dy+ A+e y ka+  +p
  EEA19173.1 144 KDYNRAIELYGKAILCKP 161
                 8************96555 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.046
                 CHHHHHHHHHHHTT-HHHHHHHH CS
       TPR_8   2 eayynlgsiylklgdyeeAkeyy 24 
                 +a+++ + +y+ l++y++A   +
  EEA19173.1 198 KALNRRAIAYEHLEQYDNALLDF 220
                 7999***************7655 PP

  == domain 3  score: 6.7 bits;  conditional E-value: 0.016
                 HHHHHHHHHHHHHH CS
       TPR_8  17 yeeAkeyyekalel 30 
                 y+eA +++ekalel
  EEA19173.1 312 YDEAAQAFEKALEL 325
                 8***********97 PP

  == domain 4  score: 5.9 bits;  conditional E-value: 0.03
                 T-HHHHHHHHHHHHHHHHH CS
       TPR_8  15 gdyeeAkeyyekaleldpd 33 
                 gd ++A e ++k +e++p+
  EEA19173.1 347 GDAQSALEDLNKSIEIQPS 365
                 89999**********9995 PP

  == domain 5  score: 1.9 bits;  conditional E-value: 0.58
                 CHHHHHHHHHHHTT-H CS
       TPR_8   2 eayynlgsiylklgdy 17 
                 ++y + +s++l+lg++
  EEA19173.1 368 QSYIKRASLHLELGKF 383
                 7899**********86 PP

  == domain 6  score: 23.4 bits;  conditional E-value: 7.1e-08
                 CHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   2 eayynlgsiylklgdyeeAkeyyekaleldpd 33 
                 ++yy+ +++++ lg++ eA + y+k ++ldp+
  EEA19173.1 405 DIYYHRAQLHFILGEFAEAAKDYQKSIDLDPS 436
                 69*****************************6 PP

  == domain 7  score: 5.2 bits;  conditional E-value: 0.049
                 HHHHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAkeyyekale 29 
                 ++ +lg +  klg   +A++++++ ++
  EEA19173.1 440 SHIQLGVTQYKLGSVASAMATFKRSVK 466
                 56799******************9876 PP

  == domain 8  score: 8.9 bits;  conditional E-value: 0.0032
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAkeyyekaleldpd 33 
                 +y+  g ++l+++dy+ A+e + ka+e++ +
  EEA19173.1 474 VYNYYGELLLDQQDYQGAIEKFDKAVEMESK 504
                 677789*********************9876 PP

  == domain 9  score: 4.5 bits;  conditional E-value: 0.082
                 TT-HHHHHHHHHHHHHHHHH. CS
       TPR_8  14 lgdyeeAkeyyekaleldpdn 34 
                 ++d++eA++ ++kal +dp++
  EEA19173.1 526 KQDFKEAESLCQKALIIDPEC 546
                 579************999986 PP

  == domain 10  score: 12.3 bits;  conditional E-value: 0.00027
                 HHHHHHHTT-HHHHHHHHHHHHHHHH CS
       TPR_8   7 lgsiylklgdyeeAkeyyekaleldp 32 
                 +++++l++g+  eA +y+ +a el++
  EEA19173.1 553 MAQLLLQQGKVAEALKYFTRAAELAR 578
                 799********************987 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.1         3   1.8e+03       1      13 [.     152     163 ..     146     179 .. 0.67
   2 ?    4.6   0.3     0.084        50       5      32 ..     189     216 ..     188     217 .. 0.86
   3 ?    2.9   0.0      0.29   1.7e+02      13      33 ..     333     353 ..     318     354 .. 0.84
   4 !    9.1   0.0     0.003       1.8       3      29 ..     357     383 ..     355     386 .. 0.92
   5 !   17.0   0.0     9e-06    0.0054       2      32 ..     393     423 ..     392     425 .. 0.94
   6 !   13.6   0.0   0.00012     0.069       2      28 ..     427     453 ..     426     459 .. 0.91
   7 !   16.6   0.0   1.2e-05    0.0072       2      34 .]     461     493 ..     460     493 .. 0.94
   8 ?    4.3   0.0       0.1        60       1      33 [.     535     567 ..     535     568 .. 0.89

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 3
      TPR_17   1 lylkaleldPnna 13 
                 ly ka+ + P+ +
  EEA19173.1 152 LYGKAILCKPD-P 163
                 56677766664.4 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.084
      TPR_17   5 aleldPnnadaynnLAelllknGdlmtA 32 
                 al  d  + +a+n +A +++++ +++ A
  EEA19173.1 189 ALVMDSEYLKALNRRAIAYEHLEQYDNA 216
                 5666778889***************988 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.29
      TPR_17  13 adaynnLAelllknGdlmtAr 33 
                  da+n++A++ + +Gd + A+
  EEA19173.1 333 GDALNQRATFTYLRGDAQSAL 353
                 589*************99997 PP

  == domain 4  score: 9.1 bits;  conditional E-value: 0.003
      TPR_17   3 lkaleldPnnadaynnLAelllknGdl 29 
                  k++e+ P+   +y  +A l+l++G++
  EEA19173.1 357 NKSIEIQPSLTQSYIKRASLHLELGKF 383
                 69**********************986 PP

  == domain 5  score: 17.0 bits;  conditional E-value: 9e-06
      TPR_17   2 ylkaleldPnnadaynnLAelllknGdlmtA 32 
                 ++ a++++++++d y+ +A+l+  +G++++A
  EEA19173.1 393 FEAAIAHNKDDPDIYYHRAQLHFILGEFAEA 423
                 899***********************99988 PP

  == domain 6  score: 13.6 bits;  conditional E-value: 0.00012
      TPR_17   2 ylkaleldPnnadaynnLAelllknGd 28 
                 y+k+++ldP+  +++ +L+++++k+G 
  EEA19173.1 427 YQKSIDLDPSFIYSHIQLGVTQYKLGS 453
                 9**********************9995 PP

  == domain 7  score: 16.6 bits;  conditional E-value: 1.2e-05
      TPR_17   2 ylkaleldPnnadaynnLAelllknGdlmtArq 34 
                 +++++++  n +d+yn+++elll + d++ A++
  EEA19173.1 461 FKRSVKKFENVPDVYNYYGELLLDQQDYQGAIE 493
                 899999999********************9986 PP

  == domain 8  score: 4.3 bits;  conditional E-value: 0.1
      TPR_17   1 lylkaleldPnnadaynnLAelllknGdlmtAr 33 
                 l++kal +dP    a   +A+lll++G+ ++A+
  EEA19173.1 535 LCQKALIIDPECDIAVGTMAQLLLQQGKVAEAL 567
                 689999999999999999**********99997 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.3   0.2    0.0061       3.6       2      26 ..     138     162 ..     137     171 .. 0.77
   2 ?   -1.8   0.2       4.3   2.6e+03      20      39 ..     189     208 ..     187     217 .. 0.66
   3 ?    4.3   0.1     0.055        33      10      23 ..     312     325 ..     310     326 .. 0.96
   4 !   10.9   0.0   0.00047      0.28       5      42 .]     344     381 ..     343     381 .. 0.94
   5 !   18.7   0.2   1.7e-06     0.001      11      40 ..     387     416 ..     386     418 .. 0.92
   6 !   31.6   0.1   1.6e-10   9.4e-08       3      42 .]     413     452 ..     411     452 .. 0.95
   7 !    9.8   0.0     0.001       0.6       1      23 [.     479     501 ..     479     505 .. 0.89
   8 ?    3.2   0.3      0.12        74       3      23 ..     556     576 ..     554     579 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0061
      TPR_11   2 dayyeqGkyeeAieaYkkAlkldPd 26 
                 +  y   +y+ Aie Y kA+  +Pd
  EEA19173.1 138 NKAYGSKDYNRAIELYGKAILCKPD 162
                 55566779***********966665 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 4.3
      TPR_11  20 AlkldPdnaeayynLGlayy 39 
                 Al  d+++  a++ ++ ay 
  EEA19173.1 189 ALVMDSEYLKALNRRAIAYE 208
                 66666666666666666664 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.055
      TPR_11  10 yeeAieaYkkAlkl 23 
                 y+eA +a++kAl+l
  EEA19173.1 312 YDEAAQAFEKALEL 325
                 9***********98 PP

  == domain 4  score: 10.9 bits;  conditional E-value: 0.00047
      TPR_11   5 yeqGkyeeAieaYkkAlkldPdnaeayynLGlayykqG 42 
                 y +G+   A+e+++k +++ P+    y +++ +++++G
  EEA19173.1 344 YLRGDAQSALEDLNKSIEIQPSLTQSYIKRASLHLELG 381
                 6789999*************************999998 PP

  == domain 5  score: 18.7 bits;  conditional E-value: 1.7e-06
      TPR_11  11 eeAieaYkkAlkldPdnaeayynLGlayyk 40 
                 ++A+ ++++A++ + d++++yy+++++++ 
  EEA19173.1 387 DGAVDDFEAAIAHNKDDPDIYYHRAQLHFI 416
                 78************************9985 PP

  == domain 6  score: 31.6 bits;  conditional E-value: 1.6e-10
      TPR_11   3 ayyeqGkyeeAieaYkkAlkldPdnaeayynLGlayykqG 42 
                 + + +G++ eA ++Y+k ++ldP++   +  LG+++yk+G
  EEA19173.1 413 LHFILGEFAEAAKDYQKSIDLDPSFIYSHIQLGVTQYKLG 452
                 67899*********************************99 PP

  == domain 7  score: 9.8 bits;  conditional E-value: 0.001
      TPR_11   1 GdayyeqGkyeeAieaYkkAlkl 23 
                 G ++ +q++y +Aie++ kA++ 
  EEA19173.1 479 GELLLDQQDYQGAIEKFDKAVEM 501
                 77899***************985 PP

  == domain 8  score: 3.2 bits;  conditional E-value: 0.12
      TPR_11   3 ayyeqGkyeeAieaYkkAlkl 23 
                 ++ +qGk  eA++ + +A +l
  EEA19173.1 556 LLLQQGKVAEALKYFTRAAEL 576
                 689*********999888876 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.2       1.3   7.7e+02      54      71 ..     139     156 ..     121     158 .. 0.70
   2 ?    6.6   0.2     0.016       9.7       3      27 ..     197     221 ..     195     229 .. 0.84
   3 !   14.8   1.1   4.3e-05     0.026      12      76 ..     304     364 ..     302     365 .. 0.88
   4 !    9.5   0.1    0.0019       1.1       5      58 ..     335     380 ..     331     399 .. 0.78
   5 !   14.5   0.0   5.4e-05     0.032       5      58 ..     406     458 ..     402     469 .. 0.85
   6 !   14.4   0.2   5.7e-05     0.034       4      72 ..     473     540 ..     470     540 .. 0.73
   7 !   17.8   1.3   5.2e-06    0.0031      13      76 ..     523     578 ..     514     578 .. 0.84
   8 !   17.1   0.7   8.2e-06    0.0049       8      36 ..     552     580 ..     544     597 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 1.3
      TPR_12  54 lyralgryeeAlelleea 71 
                   + +++y  A+el+ +a
  EEA19173.1 139 KAYGSKDYNRAIELYGKA 156
                 556677788888887766 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.016
      TPR_12   3 atalnnlaavlrrlgrydeAlelle 27 
                 ++aln++a ++ +l++yd Al  + 
  EEA19173.1 197 LKALNRRAIAYEHLEQYDNALLDFT 221
                 578989999*********9997665 PP

  == domain 3  score: 14.8 bits;  conditional E-value: 4.3e-05
      TPR_12  12 vlrrlgr.ydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                 ++++ g+ ydeA + +ekale+ +  lG+    +  +l+  ++  +++g+ + Ale l+++++i +
  EEA19173.1 304 MEQKTGEgYDEAAQAFEKALELGE--LGE---FEGDALNQRATFTYLRGDAQSALEDLNKSIEIQP 364
                 56788888***************3..565...5899********99****************9975 PP

  == domain 4  score: 9.5 bits;  conditional E-value: 0.0019
      TPR_12   5 alnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyral 58 
                 aln++a++ + +g+ + Ale l+k++ei+     p +  + ++++  + l+++l
  EEA19173.1 335 ALNQRATFTYLRGDAQSALEDLNKSIEIQ-----P-S--LTQSYIKRASLHLEL 380
                 7889************************9.....3.1..344445555554444 PP

  == domain 5  score: 14.5 bits;  conditional E-value: 5.4e-05
      TPR_12   5 alnnlaavlrrlgrydeAlellekaleia.rrllGpdhpltattlrnLgrlyral 58 
                 +++++a++++ lg+++eA + ++k++++  + +    h ++  t++ Lg + +a+
  EEA19173.1 406 IYYHRAQLHFILGEFAEAAKDYQKSIDLDpSFI--YSHIQLGVTQYKLGSVASAM 458
                 7899*************************6666..66999999999999998876 PP

  == domain 6  score: 14.4 bits;  conditional E-value: 5.7e-05
      TPR_12   4 talnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlr.nLgrlyralgryeeAlelleeal 72 
                  ++n ++++l+ +++y+ A+e ++ka+e+ +++  p+  +++   + +Lg+ ++++ +++eA++l ++al
  EEA19173.1 473 DVYNYYGELLLDQQDYQGAIEKFDKAVEMESKTK-PTAINVLPLINkALGIFQWKQ-DFKEAESLCQKAL 540
                 57878************************99883.555444444331344445666.8888888877776 PP

  == domain 7  score: 17.8 bits;  conditional E-value: 5.2e-06
      TPR_12  13 lrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                  ++ +++ eA++l++kal i      p+     ++  ++++l++++g+ +eAl+++++a ++a+
  EEA19173.1 523 FQWKQDFKEAESLCQKALIID-----PEC---DIAVGTMAQLLLQQGKVAEALKYFTRAAELAR 578
                 578899999999999999999.....654...46899999999999999999999999999876 PP

  == domain 8  score: 17.1 bits;  conditional E-value: 8.2e-06
      TPR_12   8 nlaavlrrlgrydeAlellekaleiarrl 36 
                  +a++l+++g+ +eAl+++ +a e+ar  
  EEA19173.1 552 TMAQLLLQQGKVAEALKYFTRAAELARTE 580
                 49999********************9755 PP

>> TPR_9  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.2   0.1    0.0023       1.4      10      71 ..     178     241 ..     176     243 .. 0.79
   2 !   22.7   0.1   1.3e-07   7.8e-05       9      72 ..     347     413 ..     339     414 .. 0.94
   3 !   14.0   0.0   7.1e-05     0.043      27      61 ..     402     436 ..     400     442 .. 0.94
   4 ?    6.3   0.0     0.018        11      11      55 ..     420     464 ..     417     476 .. 0.84
   5 ?    2.4   0.0      0.29   1.7e+02      15      60 ..     458     503 ..     450     512 .. 0.76
   6 !   12.8   0.1   0.00017       0.1       8      61 ..     526     579 ..     520     598 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0023
       TPR_9  10 dweralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalap..dapdaeairaq 71 
                 +we+  +     l+++++    +  R++++++l+++  Al d+ a   ++   +++ +e ++ +
  EEA19173.1 178 EWEKVVEDTSAALVMDSEYLKALNRRAIAYEHLEQYDNALLDFTASCIIDQftNRQSRESLERL 241
                 5788888888899999999999999*****************9987655544466666666665 PP

  == domain 2  score: 22.7 bits;  conditional E-value: 1.3e-07
       TPR_9   9 edweralavverllllaPddpeerrdRGlllaqlGcl...saAladLeaylalapdapdaeairaqL 72 
                  d++ al+ ++  + ++P   + +  R+ l+ +lG +    +A++d+ea++a++ d+pd++  raqL
  EEA19173.1 347 GDAQSALEDLNKSIEIQPSLTQSYIKRASLHLELGKFilcDGAVDDFEAAIAHNKDDPDIYYHRAQL 413
                 6999********************************97778********************999998 PP

  == domain 3  score: 14.0 bits;  conditional E-value: 7.1e-05
       TPR_9  27 ddpeerrdRGlllaqlGclsaAladLeaylalapd 61 
                 ddp+ ++ R++l++ lG +++A++d +  ++l+p+
  EEA19173.1 402 DDPDIYYHRAQLHFILGEFAEAAKDYQKSIDLDPS 436
                 89*****************************9995 PP

  == domain 4  score: 6.3 bits;  conditional E-value: 0.018
       TPR_9  11 weralavverllllaPddpeerrdRGlllaqlGclsaAladLeay 55 
                 +++a + ++  + l+P  ++ +   G+ +++lG ++ A+a + + 
  EEA19173.1 420 FAEAAKDYQKSIDLDPSFIYSHIQLGVTQYKLGSVASAMATFKRS 464
                 788999999999999999999999999999999999999988775 PP

  == domain 5  score: 2.4 bits;  conditional E-value: 0.29
       TPR_9  15 lavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalap 60 
                 +a+  r +  + + p+ +   G ll  + ++++A++ ++ +++++ 
  EEA19173.1 458 MATFKRSVKKFENVPDVYNYYGELLLDQQDYQGAIEKFDKAVEMES 503
                 555555555555666666667999999*************998865 PP

  == domain 6  score: 12.8 bits;  conditional E-value: 0.00017
       TPR_9   8 eedweralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalapd 61 
                 ++d+ +a   ++  l+++P+    +   ++ll q+G +++Al+ + ++++la  
  EEA19173.1 526 KQDFKEAESLCQKALIIDPECDIAVGTMAQLLLQQGKVAEALKYFTRAAELART 579
                 6899999******************************************99983 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.1       2.2   1.3e+03      46      66 ..     116     135 ..     115     136 .. 0.88
   2 ?    1.2   0.0      0.92   5.5e+02       2      18 ..     141     157 ..     140     171 .. 0.83
   3 ?    2.3   0.3      0.42   2.5e+02      18      44 ..     190     216 ..     183     218 .. 0.87
   4 ?    2.9   1.9      0.27   1.6e+02       7      45 ..     312     360 ..     304     363 .. 0.73
   5 ?    1.0   0.0       1.1   6.3e+02       4      40 ..     346     382 ..     343     383 .. 0.79
   6 !   13.6   0.1   0.00013     0.075       9      45 ..     388     424 ..     387     425 .. 0.94
   7 !   15.8   0.0   2.6e-05     0.015       5      59 ..     418     472 ..     415     479 .. 0.91
   8 !    7.9   0.0    0.0075       4.5       1      23 [.     482     504 ..     482     512 .. 0.88
   9 !   22.4   0.4   2.1e-07   0.00013       5      56 ..     527     578 ..     526     587 .. 0.92

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 2.2
      TPR_19  46 alLdalpeedpddaryasLlA 66 
                  ++d l ee+++ a++a+L+A
  EEA19173.1 116 STVDSLSEETRK-AYAAKLKA 135
                 57899*******.******99 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.92
      TPR_19   2 laegdyaeAlalleqal 18 
                 + ++dy +A++l+ +a+
  EEA19173.1 141 YGSKDYNRAIELYGKAI 157
                 67889*******99985 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.42
      TPR_19  18 lqedpknaearllLAeallalgqldeA 44 
                 l  d +++ a+ + A+a+  l q+d A
  EEA19173.1 190 LVMDSEYLKALNRRAIAYEHLEQYDNA 216
                 556889999****************98 PP

  == domain 4  score: 2.9 bits;  conditional E-value: 0.27
      TPR_19   7 yaeAlalleqalqe..........dpknaearllLAeallalgqldeAe 45 
                 y+eA++++e+al+            ++ a   +l  +a+ al +l++ +
  EEA19173.1 312 YDEAAQAFEKALELgelgefegdaLNQRATFTYLRGDAQSALEDLNKSI 360
                 99**********6655555544336666666667788888888887765 PP

  == domain 5  score: 1.0 bits;  conditional E-value: 1.1
      TPR_19   4 egdyaeAlalleqalqedpk..naearllLAeallalgq 40 
                 +gd ++Al+ l + ++  p   +++++   A ++l+lg 
  EEA19173.1 346 RGDAQSALEDLNKSIEIQPSltQSYIKR--ASLHLELGK 382
                 79***********999999855555555..888888876 PP

  == domain 6  score: 13.6 bits;  conditional E-value: 0.00013
      TPR_19   9 eAlalleqalqedpknaearllLAeallalgqldeAe 45 
                  A++ +e+a++++ +++++ +  A++++ lg+++eA 
  EEA19173.1 388 GAVDDFEAAIAHNKDDPDIYYHRAQLHFILGEFAEAA 424
                 68999******************************96 PP

  == domain 7  score: 15.8 bits;  conditional E-value: 2.6e-05
      TPR_19   5 gdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpdda 59 
                 g +aeA++ +++ ++ dp   +  ++L   +++lg ++ A+a+ ++  +++ + +
  EEA19173.1 418 GEFAEAAKDYQKSIDLDPSFIYSHIQLGVTQYKLGSVASAMATFKRSVKKFENVP 472
                 89*******************************************9998887755 PP

  == domain 8  score: 7.9 bits;  conditional E-value: 0.0075
      TPR_19   1 llaegdyaeAlalleqalqedpk 23 
                 ll+++dy+ A++ + +a + + k
  EEA19173.1 482 LLDQQDYQGAIEKFDKAVEMESK 504
                 79***************998765 PP

  == domain 9  score: 22.4 bits;  conditional E-value: 2.1e-07
      TPR_19   5 gdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedp 56 
                 +d+ eA +l ++al  dp+ + a   +A++ll++g ++eA +   ++ e ++
  EEA19173.1 527 QDFKEAESLCQKALIIDPECDIAVGTMAQLLLQQGKVAEALKYFTRAAELAR 578
                 79***************************************99999888766 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.2      0.47   2.8e+02       3      21 ..     199     217 ..     197     222 .. 0.89
   2 ?    4.3   0.1      0.15        92      15      31 ..     309     326 ..     296     332 .. 0.78
   3 ?    0.7   0.0       2.1   1.3e+03       3      33 ..     335     365 ..     333     368 .. 0.83
   4 !   12.3   0.1   0.00041      0.24       5      44 .]     371     413 ..     367     413 .. 0.87
   5 !   14.8   0.0   6.2e-05     0.037       1      41 [.     404     444 ..     404     447 .. 0.87
   6 ?    7.1   0.0      0.02        12       6      44 .]     443     481 ..     439     481 .. 0.89
   7 ?    6.3   0.0     0.035        21       2      29 ..     473     500 ..     472     509 .. 0.88
   8 ?    3.5   0.0      0.28   1.7e+02      14      42 ..     526     554 ..     518     555 .. 0.80
   9 !   10.9   0.6    0.0011      0.67       7      32 ..     553     578 ..     549     586 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.47
      TPR_14   3 allalaeallalGdpdeAi 21 
                 al ++a a+++l+++d A+
  EEA19173.1 199 ALNRRAIAYEHLEQYDNAL 217
                 77899***********986 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.15
      TPR_14  15 Gd.pdeAiallrralala 31 
                 G+ +deA++++++al+l+
  EEA19173.1 309 GEgYDEAAQAFEKALELG 326
                 4458***********976 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 2.1
      TPR_14   3 allalaeallalGdpdeAiallrralalaPd 33 
                 al ++a + + +Gd + A++ l++ ++ +P+
  EEA19173.1 335 ALNQRATFTYLRGDAQSALEDLNKSIEIQPS 365
                 55677777788999******99999999985 PP

  == domain 4  score: 12.3 bits;  conditional E-value: 0.00041
      TPR_14   5 lalaeallalGd...pdeAiallrralalaPddaeawlllaql 44 
                  ++a+++l+lG+    d+A++ +++a+a++ dd++++++ aql
  EEA19173.1 371 IKRASLHLELGKfilCDGAVDDFEAAIAHNKDDPDIYYHRAQL 413
                 578899999998665688***********************97 PP

  == domain 5  score: 14.8 bits;  conditional E-value: 6.2e-05
      TPR_14   1 peallalaeallalGdpdeAiallrralalaPddaeawlll 41 
                 p+ ++ +a++++ lG+++eA++ +++ ++l+P++   +++l
  EEA19173.1 404 PDIYYHRAQLHFILGEFAEAAKDYQKSIDLDPSFIYSHIQL 444
                 57899***************************976655555 PP

  == domain 6  score: 7.1 bits;  conditional E-value: 0.02
      TPR_14   6 alaeallalGdpdeAiallrralalaPddaeawlllaql 44 
                 +l+   + lG  + A+a ++r ++++ + ++++ ++++l
  EEA19173.1 443 QLGVTQYKLGSVASAMATFKRSVKKFENVPDVYNYYGEL 481
                 567778899***********************9999986 PP

  == domain 7  score: 6.3 bits;  conditional E-value: 0.035
      TPR_14   2 eallalaeallalGdpdeAiallrrala 29 
                 +++  ++e+ll ++d+++Ai+ +++a++
  EEA19173.1 473 DVYNYYGELLLDQQDYQGAIEKFDKAVE 500
                 567789******************9987 PP

  == domain 8  score: 3.5 bits;  conditional E-value: 0.28
      TPR_14  14 lGdpdeAiallrralalaPddaeawllla 42 
                  +d++eA+ l+++al  +P+ + a   +a
  EEA19173.1 526 KQDFKEAESLCQKALIIDPECDIAVGTMA 554
                 579*************9999776665555 PP

  == domain 9  score: 10.9 bits;  conditional E-value: 0.0011
      TPR_14   7 laeallalGdpdeAiallrralalaP 32 
                 +a++ll++G+ +eA++++ ra +la 
  EEA19173.1 553 MAQLLLQQGKVAEALKYFTRAAELAR 578
                 89*******************98765 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0      0.17     1e+02      14      27 ..     145     156 ..     143     163 .. 0.87
   2 ?    3.3   0.2      0.16        98       1      19 [.     199     217 ..     199     227 .. 0.88
   3 ?    3.4   0.1      0.16        97      15      28 ..     312     325 ..     312     331 .. 0.82
   4 ?   -1.5   0.0         6   3.6e+03      12      20 ..     390     398 ..     372     405 .. 0.54
   5 !    7.8   0.0    0.0061       3.7       3      32 ..     408     435 ..     406     438 .. 0.81
   6 !    8.8   0.0    0.0031       1.8       3      29 ..     476     502 ..     474     507 .. 0.82
   7 ?    4.6   0.0     0.066        39      13      26 ..     527     540 ..     518     548 .. 0.77
   8 !   14.3   0.1   5.1e-05     0.031       5      34 ..     553     582 ..     549     584 .. 0.92

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.17
       TPR_7  14 dyeeAielyeqsLa 27 
                 dy +Aiely +  a
  EEA19173.1 145 DYNRAIELYGK--A 156
                 89*******99..5 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.16
       TPR_7   1 aLlnLarlysrlGdyeeAi 19 
                 aL++ a +y+ l +y++A+
  EEA19173.1 199 ALNRRAIAYEHLEQYDNAL 217
                 79999*************8 PP

  == domain 3  score: 3.4 bits;  conditional E-value: 0.16
       TPR_7  15 yeeAielyeqsLal 28 
                 y+eA++ +e++L+l
  EEA19173.1 312 YDEAAQAFEKALEL 325
                 9*********6655 PP

  == domain 4  score: -1.5 bits;  conditional E-value: 6
       TPR_7  12 lGdyeeAie 20 
                 + d+e Ai 
  EEA19173.1 390 VDDFEAAIA 398
                 234444443 PP

  == domain 5  score: 7.8 bits;  conditional E-value: 0.0061
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLaltkdp 32 
                 +  a+l++ lG+++eA++ y++   ++ dp
  EEA19173.1 408 YHRAQLHFILGEFAEAAKDYQK--SIDLDP 435
                 566899999*************..666655 PP

  == domain 6  score: 8.8 bits;  conditional E-value: 0.0031
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLalt 29 
                 ++ ++l  +++dy+ Aie + ++ +++
  EEA19173.1 476 NYYGELLLDQQDYQGAIEKFDKAVEME 502
                 6668999**************955554 PP

  == domain 7  score: 4.6 bits;  conditional E-value: 0.066
       TPR_7  13 GdyeeAielyeqsL 26 
                 +d++eA++l++++L
  EEA19173.1 527 QDFKEAESLCQKAL 540
                 8***********55 PP

  == domain 8  score: 14.3 bits;  conditional E-value: 5.1e-05
       TPR_7   5 LarlysrlGdyeeAielyeqsLaltkdped 34 
                 +a+l  ++G+ +eA+++++++ +l++ +++
  EEA19173.1 553 MAQLLLQQGKVAEALKYFTRAAELARTEGE 582
                 89**********************999886 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.1      0.39   2.3e+02      34      49 ..     141     156 ..     118     183 .. 0.76
   2 !    7.4   0.0    0.0086       5.1       5      71 ..     312     382 ..     309     384 .. 0.76
   3 !   16.9   0.0   9.3e-06    0.0056      14      80 ..     395     462 ..     385     464 .. 0.91
   4 ?    3.5   0.0      0.14        84      27      55 ..     476     505 ..     463     513 .. 0.78
   5 !   11.7   0.1   0.00038      0.23       1      79 [.     484     570 ..     484     573 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.39
                 HHTT-HHHHHHHHHCT CS
      ANAPC3  34 ylngqykrAyellrka 49 
                 y +++y+rA+el+ ka
  EEA19173.1 141 YGSKDYNRAIELYGKA 156
                 77899******99998 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0086
                 HHHHHHHHHHHH....HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCTSHHHC-HHHHHHHHHHH.HHTT- CS
      ANAPC3   5 yknAiflaerlla...aetespedayllAlclylngqykrAyellrkaklnskslgcrylfAqcl.lkLkk 71 
                 y++A   +e++l+         +++   A   yl+g+ ++A+e l+k+ +   sl   y++  +l l+L+k
  EEA19173.1 312 YDEAAQAFEKALElgeLGEFEGDALNQRATFTYLRGDAQSALEDLNKSIEIQPSLTQSYIKRASLhLELGK 382
                 777888888888544255556666777799******************77777888888877666368877 PP

  == domain 3  score: 16.9 bits;  conditional E-value: 9.3e-06
                 HHH.HHH--HHHHHHH.HHHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHHH- CS
      ANAPC3  14 rllaaetespedayll.AlclylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaaLe 80 
                  +  a+++++ d+y++ A+ ++ +g++ +A + ++k+ +l+++ + +++ ++ +++kL+++  A a+++
  EEA19173.1 395 AAI-AHNKDDPDIYYHrAQLHFILGEFAEAAKDYQKSiDLDPSFIYSHIQLGVTQYKLGSVASAMATFK 462
                 555.788899999**99*******************************************999998886 PP

  == domain 4  score: 3.5 bits;  conditional E-value: 0.14
                 HHHHHHHHHTT-HHHHHHHHHCT.SHHHC- CS
      ANAPC3  27 yllAlclylngqykrAyellrka.klnsks 55 
                  ++++ l+ +++y+ A+e ++ka + +sk+
  EEA19173.1 476 NYYGELLLDQQDYQGAIEKFDKAvEMESKT 505
                 467999999999999999999996666655 PP

  == domain 5  score: 11.7 bits;  conditional E-value: 0.00038
                 HTT-HHHHHHHHHHHH..HHH--HHHHHHH.....HHHHHHTT-.HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHHH CS
      ANAPC3   1 dqnnyknAiflaerlla.aetespedayll.....Alclylngq.ykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaaL 79 
                 dq++y+ Ai  ++++++  ++  p ++  l     Al  ++ +q +k+A  l++ka  ++++   +  ++Aq ll+++k+ eA++ +
  EEA19173.1 484 DQQDYQGAIEKFDKAVEmESKTKPTAINVLplinkALGIFQWKQdFKEAESLCQKAlIIDPECDIAVGTMAQLLLQQGKVAEALKYF 570
                 688899999999999964335566666655555669999998888***********999999999999***************9877 PP

>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0       2.2   1.3e+03      16      29 ..     144     157 ..     141     160 .. 0.84
   2 ?    1.6   0.1      0.46   2.8e+02       4      24 ..     199     219 ..     197     226 .. 0.87
   3 ?    2.9   0.2      0.18   1.1e+02      18      31 ..     312     325 ..     302     327 .. 0.91
   4 ?    3.1   0.1      0.15        90       4      31 ..     335     362 ..     334     363 .. 0.91
   5 ?   -2.2   0.0       7.1   4.2e+03      19      30 ..     387     398 ..     386     398 .. 0.89
   6 ?    5.9   0.0      0.02        12       8      30 ..     410     432 ..     405     433 .. 0.85
   7 ?    4.2   0.0     0.072        43       5      31 ..     475     501 ..     473     505 .. 0.89
   8 ?    2.5   0.0      0.23   1.4e+02      16      31 ..     527     542 ..     522     542 .. 0.86
   9 !    9.7   0.2    0.0013      0.76       8      33 ..     553     578 ..     551     581 .. 0.91

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 2.2
      TPR_10  16 grydeAealleeal 29 
                 ++y++A +l+ +a+
  EEA19173.1 144 KDYNRAIELYGKAI 157
                 78999*****9998 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.46
      TPR_10   4 slnNLanalrqrgrydeAeal 24 
                 +ln  a+a+ ++ +yd A+ +
  EEA19173.1 199 ALNRRAIAYEHLEQYDNALLD 219
                 89999************9865 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.18
      TPR_10  18 ydeAealleealai 31 
                 ydeA + +e+al++
  EEA19173.1 312 YDEAAQAFEKALEL 325
                 89**********97 PP

  == domain 4  score: 3.1 bits;  conditional E-value: 0.15
      TPR_10   4 slnNLanalrqrgrydeAealleealai 31 
                 +ln  a   + rg+ + A+++l ++++i
  EEA19173.1 335 ALNQRATFTYLRGDAQSALEDLNKSIEI 362
                 7899999999***************998 PP

  == domain 5  score: -2.2 bits;  conditional E-value: 7.1
      TPR_10  19 deAealleeala 30 
                 d+A++++e a+a
  EEA19173.1 387 DGAVDDFEAAIA 398
                 78********97 PP

  == domain 6  score: 5.9 bits;  conditional E-value: 0.02
      TPR_10   8 LanalrqrgrydeAealleeala 30 
                  a +++ +g+++eA ++++++++
  EEA19173.1 410 RAQLHFILGEFAEAAKDYQKSID 432
                 5788999*************996 PP

  == domain 7  score: 4.2 bits;  conditional E-value: 0.072
      TPR_10   5 lnNLanalrqrgrydeAealleealai 31 
                 +n  + +l ++++y++A + +++a+++
  EEA19173.1 475 YNYYGELLLDQQDYQGAIEKFDKAVEM 501
                 8999*************9999999886 PP

  == domain 8  score: 2.5 bits;  conditional E-value: 0.23
      TPR_10  16 grydeAealleealai 31 
                 ++++eAe l+++al i
  EEA19173.1 527 QDFKEAESLCQKALII 542
                 6899*********965 PP

  == domain 9  score: 9.7 bits;  conditional E-value: 0.0013
      TPR_10   8 LanalrqrgrydeAealleealairr 33 
                 +a +l q+g+ +eA++++ +a ++ r
  EEA19173.1 553 MAQLLLQQGKVAEALKYFTRAAELAR 578
                 6899*****************99877 PP

>> TPR_MalT  MalT-like TPR region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.1       9.2   5.5e+03     233     253 ..     192     212 ..     175     244 .. 0.56
   2 ?    0.3   0.1      0.59   3.5e+02     179     227 ..     314     358 ..     306     384 .. 0.49
   3 !    9.1   0.0    0.0013      0.76      63     187 ..     420     539 ..     403     545 .. 0.77
   4 !   19.5   0.6   8.6e-07   0.00051      46     216 ..     444     602 ..     440     615 .. 0.76

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 9.2
    TPR_MalT 233 dddnhflelelrnlarvllal 253
                  d+++++ l++r +a+ +l++
  EEA19173.1 192 MDSEYLKALNRRAIAYEHLEQ 212
                 344455555555555544444 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.59
    TPR_MalT 179 eAetllekaeelaresnfhvdwlanaeevrvrlwlaqgdlaaaerwlea 227
                 eA++++eka el +  +f  d+l      r ++  ++gd ++a++ l +
  EEA19173.1 314 EAAQAFEKALELGELGEFEGDALNQ----RATFTYLRGDAQSALEDLNK 358
                 4444444444444444444333321....22222334444444443333 PP

  == domain 3  score: 9.1 bits;  conditional E-value: 0.0013
    TPR_MalT  63 lqeaekla.rqadslhvallallqqaeilvaqGrLheAletyeqalqlateqglqqlplvgfllvlladllyEwndLeeAeqhlqeGielleqlep..e 158
                 ++ea k   +++d  +  +++ +q++ ++ + G+   A+ t++++ +        +++ v  ++ ++++ll+++ d ++A +  ++++e+  + +p   
  EEA19173.1 420 FAEAAKDYqKSIDLDPSFIYSHIQLGVTQYKLGSVASAMATFKRSVK--------KFENVPDVYNYYGELLLDQQDYQGAIEKFDKAVEMESKTKPtaI 510
                 44444433122333355689999999999999999999999999998........455556677788**************************977324 PP

    TPR_MalT 159 aaldayvllarialaqGdleeAetlleka 187
                   l+       i + + d +eAe+l++ka
  EEA19173.1 511 NVLPLINKALGIFQWKQDFKEAESLCQKA 539
                 45688888899****************99 PP

  == domain 4  score: 19.5 bits;  conditional E-value: 8.6e-07
    TPR_MalT  46 lGeasllqGdleaAlqalqeaeklarqadslhvallallqqaeilvaqGrLheAletyeqalqlateqglqqlplvgfllvlladllyEwndLeeAeqh 144
                 lG ++   G +++A ++++  +k    ++ ++  ++ ++  +e+l  q + + A+e + +a ++  +++ +++ +  ++   l+  ++ + d++eAe  
  EEA19173.1 444 LGVTQYKLGSVASAMATFKRSVKKF--ENVPD--VYNYY--GELLLDQQDYQGAIEKFDKAVEMESKTKPTAINVLPLINKALGIFQW-KQDFKEAESL 535
                 6777777777777766666555433..33333..44455..8999******************8888888888888888888887777.579******* PP

    TPR_MalT 145 lqeGielleqlepeaaldayvllarialaqGdleeAetllekaeelaresnfhvdwlanaeevrvrlwlaqg 216
                 +q+++ +  +   ++   a  ++a++ l+qG++ eA++++ +a elar++   + +++ ae++r +l ++++
  EEA19173.1 536 CQKALIIDPEC--DI---AVGTMAQLLLQQGKVAEALKYFTRAAELARTEGEVINAISYAEATRTQLEVQEK 602
                 ****5554444..22...446899999**********************99989999999999988765554 PP

>> SHNi-TPR  SHNi-TPR
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0      0.58   3.5e+02      22      31 ..     144     153 ..     143     155 .. 0.88
   2 ?   -0.4   0.1       1.4   8.3e+02      15      27 ..     211     223 ..     210     224 .. 0.93
   3 ?    3.9   0.0     0.062        37      17      30 ..     312     325 ..     309     327 .. 0.92
   4 ?    5.4   0.1     0.021        12      20      33 ..     352     365 ..     350     369 .. 0.87
   5 !    8.1   0.1    0.0031       1.8      17      30 ..     420     433 ..     418     433 .. 0.92
   6 ?    0.6   0.0      0.65   3.9e+02       2      35 ..     473     506 ..     472     508 .. 0.76

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.58
    SHNi-TPR  22 eDlrkaLeLr 31 
                 +D+++a+eL+
  EEA19173.1 144 KDYNRAIELY 153
                 8*******97 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 1.4
    SHNi-TPR  15 enFpqAveDlrka 27 
                 e+++ A+ D++++
  EEA19173.1 211 EQYDNALLDFTAS 223
                 89********997 PP

  == domain 3  score: 3.9 bits;  conditional E-value: 0.062
    SHNi-TPR  17 FpqAveDlrkaLeL 30 
                 +++A++ ++kaLeL
  EEA19173.1 312 YDEAAQAFEKALEL 325
                 9************9 PP

  == domain 4  score: 5.4 bits;  conditional E-value: 0.021
    SHNi-TPR  20 AveDlrkaLeLreq 33 
                 A+eDl+k++e++ +
  EEA19173.1 352 ALEDLNKSIEIQPS 365
                 99*********966 PP

  == domain 5  score: 8.1 bits;  conditional E-value: 0.0031
    SHNi-TPR  17 FpqAveDlrkaLeL 30 
                 F +A++D++k+++L
  EEA19173.1 420 FAEAAKDYQKSIDL 433
                 89*********987 PP

  == domain 6  score: 0.6 bits;  conditional E-value: 0.65
    SHNi-TPR   2 dvydlLGEislEnenFpqAveDlrkaLeLreqll 35 
                 dvy+  GE+ l +  +  A+e ++ka+e   +++
  EEA19173.1 473 DVYNYYGELLLDQQDYQGAIEKFDKAVEMESKTK 506
                 7888888888888888889999999998665555 PP

>> IPPT  IPP transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.3   8.5e-05     0.051      40     106 ..      29      95 ..       8     155 .. 0.64
   2 ?    2.8   0.0      0.15        90      91     216 ..     228     373 ..     194     374 .. 0.61
   3 ?   -0.8   0.0       1.8   1.1e+03     164     192 ..     557     595 ..     511     614 .. 0.60

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 8.5e-05
                 HHHHHHHHHHHHHHTT-EEEEEES-HHHHHHHHCTG-S-...-B--HHHHHHHHHHHHHSHHHHHHHHHH CS
        IPPT  40 FqkdalkaieeilargkipilvGGTglYikallegldel...peadeelraeleeeaeeeglealheelk 106
                 ++++ ++++   +  g  ++++GGT +Y+ +     ++    p+++++ r++ +++ae e+++a  ++++
  EEA19173.1  29 WVSENKAVV--YTVAGIAVVVTGGTVYYLSTSSSSKPQEpaqPKKSKSQRRKEKKKAE-EEKKAQEAKVA 95 
                 555555554..33568899***********9997763332332222222222222221.22222222222 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.15
                 HHHHHSHHHHHHHHHHHC-HHHHTTS-TT-HHHHHHHHHH..HHHHSS-HH...................ECEEEEEECSHHHHHHHHHHHHHHHHHTT CS
        IPPT  91 eeaeeeglealheelkevdpeaaakihpndrqRiiRalev..yeetgkpls...................ellviglesdreelyeridkRvdemleaG 168
                 +  ++++ e+l + lk+v ++ a+ i   + +R+  a  v  y ++ +p +                   +  ++++e+++ e y++ ++ +++ le G
  EEA19173.1 228 QFTNRQSRESLERLLKKVAEKKAKVIMEAKGKRLPGATFVgnYLQSFRPKTipagldsedldeetgkgqlRKGYLAMEQKTGEGYDEAAQAFEKALELG 326
                 323445577899999999999999999999999999988854433333333444444444444444443333677777788889999999999999999 PP

                 HHHHHHHHHHCCCCSTTSHHHHHHHTTSS-.....HHHHHHHHHHHHHHHHHH CS
        IPPT 169 lleEvekllakalqaigykelleylegels.....leeaieklkaatrqyaKr 216
                  l E e        a+  + ++ yl+g+ +     l++ ie     t+ y+Kr
  EEA19173.1 327 ELGEFEG------DALNQRATFTYLRGDAQsaledLNKSIEIQPSLTQSYIKR 373
                 8888877......6777788888887753212111444444444456666665 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 1.8
                 HHHTTHHHHHHHHHH..........CCCCSTTSHHHHHH CS
        IPPT 164 mleaGlleEveklla..........kalqaigykelley 192
                 +l++G ++E+ k ++          ++++ai y e+++ 
  EEA19173.1 557 LLQQGKVAEALKYFTraaelartegEVINAISYAEATRT 595
                 455555555555443333333333223566666655543 PP

>> DUF2397  Protein of unknown function (DUF2397)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   1.3   8.7e-06    0.0052     367     460 ..      57     152 ..      51     162 .. 0.77
   2 ?   -4.1   0.0         9   5.4e+03     214     232 ..     234     252 ..     224     260 .. 0.70
   3 ?   -3.1   0.1       4.5   2.7e+03     130     167 ..     394     431 ..     389     432 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 8.7e-06
     DUF2397 367 rgrrerrgrpsrvadrsaerarlaeealrerea.eaaalaeLatagkv.rlselgvlseearrlLLelLgkAlaardpvdgevratktdggleirl 460
                 + + +++++p++ + ++ +r++ +++a++e++a ea+ +ae ++  kv +++el++++e +++ L e   kA aa+ +++g+   +++d+ + i+l
  EEA19173.1  57 TSSSSKPQEPAQPKKSKSQRRKEKKKAEEEKKAqEAKVAAEEVKTAKVeDVDELPEVDESTVDSLSEETRKAYAAKLKAAGNKAYGSKDYNRAIEL 152
                 5566666777777777777777777776665540444455556666666****************************9999999999999998887 PP

  == domain 2  score: -4.1 bits;  conditional E-value: 9
     DUF2397 214 eeagverllaraaereari 232
                 +++ +erll+++ae++a+ 
  EEA19173.1 234 SRESLERLLKKVAEKKAKV 252
                 5777888888888887765 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 4.5
     DUF2397 130 aelaeedeaddevaellrelferfekLaenaadFlasL 167
                 +++ +++++d++++ + ++l+  + ++ae+a+d+++s+
  EEA19173.1 394 EAAIAHNKDDPDIYYHRAQLHFILGEFAEAAKDYQKSI 431
                 5555566666689999999999999*********9875 PP

>> MAS20  MAS20 protein import receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.4   1.9   0.00022      0.13      27     108 ..      70     163 ..      41     165 .. 0.58
   2 ?   -1.2   0.1       3.4     2e+03      78     103 ..     296     324 ..     230     327 .. 0.56
   3 ?    3.2   0.0      0.14        86      82     106 ..     479     503 ..     476     513 .. 0.88
   4 ?    4.1   0.1     0.078        47      81     115 ..     553     587 ..     550     593 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00022
       MAS20  27 kklrerrkkqakaakeeeeaekaekkk...kealeeakeelp..tda........eevekfFleevqlGEellaqgeeeeaaehlynAlkvcpqP 108
                 kk + +r+k++k+a+ee++a++a+ ++   k+a  e+ +elp  + +        e+++++  +  + G++   +++++ a+e   +A+ + p P
  EEA19173.1  70 KKSKSQRRKEKKKAEEEKKAQEAKVAAeevKTAKVEDVDELPevD-EstvdslseETRKAYAAKLKAAGNKAYGSKDYNRAIELYGKAILCKPDP 163
                 444444455444444444444444433344333333333355431.2234445535555555555567888888888888888888888888777 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 3.4
       MAS20  78 evqlGEellaq...geeeeaaehlynAlk 103
                 ++++G   ++q   + ++eaa+++ +Al 
  EEA19173.1 296 QLRKGYLAMEQktgEGYDEAAQAFEKALE 324
                 44555555555555567777777777775 PP

  == domain 3  score: 3.2 bits;  conditional E-value: 0.14
       MAS20  82 GEellaqgeeeeaaehlynAlkvcp 106
                 GE ll q++++ a+e++ +A+ + +
  EEA19173.1 479 GELLLDQQDYQGAIEKFDKAVEMES 503
                 9*******************98755 PP

  == domain 4  score: 4.1 bits;  conditional E-value: 0.078
       MAS20  81 lGEellaqgeeeeaaehlynAlkvcpqPqeLlqil 115
                 +++ ll+qg++ ea++ +++A  +  + +e+++ +
  EEA19173.1 553 MAQLLLQQGKVAEALKYFTRAAELARTEGEVINAI 587
                 56779999*****************9999999865 PP

>> AP3D1  AP-3 complex subunit delta-1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   4.7     3e-05     0.018      67     141 ..      52     121 ..      13     129 .. 0.61

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 3e-05
       AP3D1  67 dkyleeeesrkakkkakeekkkkkkkkkkkkkkkkkkkkkkeeesseseeddkplhavnrttlemPegaels.Dse 141
                   yl++++s+k ++ a+     kk+k ++ k kkk +++kk +e ++  e+ k +++ + ++ e+Pe  e++ Ds 
  EEA19173.1  52 VYYLSTSSSSKPQEPAQ----PKKSKSQRRKEKKKAEEEKKAQEAKVAAEEVKTAKV-E-DVDELPEVDESTvDSL 121
                 45666633333333333....444444444444445566666666777776666554.4.6889999777766664 PP

>> DUF2681  Protein of unknown function (DUF2681)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.8   5.2e-05     0.031      26      59 ..      72     105 ..      35     122 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 5.2e-05
     DUF2681  26 kkarkknaklqaekqqlkvekavaeaevknakvk 59 
                  k++++ +k++ae+++ ++e++va++evk akv 
  EEA19173.1  72 SKSQRRKEKKKAEEEKKAQEAKVAAEEVKTAKVE 105
                 355599999999*****************99986 PP

>> TSGP1  Tick salivary peptide group 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.2     8e-05     0.048      70     116 ..      46      91 ..      17      96 .. 0.59

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 8e-05
       TSGP1  70 vCqeGeC.ylatvssdkPkdsddgdpaetekpkkkkkkekktkkkkek 116
                 v   G+  yl+t+ss kP+++   +p+++++ ++k+kk+ +++kk ++
  EEA19173.1  46 VVTGGTVyYLSTSSSSKPQEP--AQPKKSKSQRRKEKKKAEEEKKAQE 91 
                 445555426788888899988..5666666666666666655555544 PP

>> TPR_4  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.0     0.057        34       5      21 ..     408     424 ..     404     424 .. 0.90
   2 ?   -1.0   0.0       7.1   4.3e+03       3      23 ..     440     460 ..     439     463 .. 0.84
   3 ?    5.7   0.2     0.047        28       7      21 ..     553     567 ..     549     567 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.057
       TPR_4   5 laLArallalGdldeAr 21 
                 + +A++++ lG+++eA+
  EEA19173.1 408 YHRAQLHFILGEFAEAA 424
                 789*************6 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 7.1
       TPR_4   3 allaLArallalGdldeAral 23 
                  ++ L+ +++ lG  + A a+
  EEA19173.1 440 SHIQLGVTQYKLGSVASAMAT 460
                 5899*********99988776 PP

  == domain 3  score: 5.7 bits;  conditional E-value: 0.047
       TPR_4   7 LArallalGdldeAr 21 
                 +A++ll++G  +eA+
  EEA19173.1 553 MAQLLLQQGKVAEAL 567
                 79************6 PP

>> DUF2561  Protein of unknown function (DUF2561)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.6   0.00035      0.21      61     146 ..      32     119 ..      23     131 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00035
     DUF2561  61 httwvLyavivvsalvivgavPlLLrarrvaeaePaarargaperaaaapargadapaer..aeaeeasaekaealreaaewssaavd 146
                 +   v+y+v +++++v  g v  L  +     +ePa++++++++r  +++++  ++ a++  + aee+++ k+e + e  e  + +vd
  EEA19173.1  32 ENKAVVYTVAGIAVVVTGGTVYYLSTSSSSKPQEPAQPKKSKSQRRKEKKKAEEEKKAQEakVAAEEVKTAKVEDVDELPEVDESTVD 119
                 55679********************9999999********999999999999888888882244455566666666666666666666 PP

>> BCIP  p21-C-terminal region-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.5     0.036        21     159     194 ..      54      97 ..      14     107 .. 0.57
   2 ?    5.5   0.0     0.022        13      12      55 ..     526     569 ..     516     600 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.036
        BCIP 159 ylilskvykevkskede.......kkkkkkkkkkkkkkk....seed 194
                 yl  s   k +++++ +       k   +kkk++++kk+     + +
  EEA19173.1  54 YLSTSSSSKPQEPAQPKksksqrrK---EKKKAEEEKKAqeakVAAE 97 
                 5555554444444433344332211...1111111111122333444 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.022
        BCIP  12 eeedfhgiknLlrqlff.ldaeevdlseLadlileqktvGsvvkv 55 
                 + +df+  + L ++ +  + + ++ ++ +a+l+l+q +v   +k 
  EEA19173.1 526 K-QDFKEAESLCQKALIiDPECDIAVGTMAQLLLQQGKVAEALKY 569
                 3.79********9655547777****************9999887 PP

>> U1snRNP70_N  U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   2.0   0.00019      0.11      39      86 ..      43      97 ..      26     103 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 0.00019
  U1snRNP70_N 39 vaafl........selkedeeeqeppektetkeekkererkekkekkeekleeale 86
                 +a ++        s    ++++qep ++ ++k +++++++k+++ekk+++++ a e
   EEA19173.1 43 IAVVVtggtvyylSTSS-SSKPQEPAQPKKSKSQRRKEKKKAEEEKKAQEAKVAAE 97
                 55555444333323332.56788888889999999999999999999998887666 PP

>> DUF3856  Domain of Unknown Function (DUF3856)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.5       5.5   3.3e+03      18      64 ..      78     124 ..      70     156 .. 0.59
   2 ?    1.4   0.0      0.51   3.1e+02      99     125 ..     196     222 ..     165     236 .. 0.80
   3 ?    0.8   0.0      0.76   4.5e+02      21      39 ..     308     326 ..     295     382 .. 0.79
   4 ?   -0.2   0.0       1.5   9.2e+02      23      39 ..     418     434 ..     408     499 .. 0.73
   5 ?   -1.1   0.0         3   1.8e+03      20      39 ..     483     503 ..     466     509 .. 0.69
   6 ?    7.5   0.0    0.0066         4      78     104 ..     563     589 ..     547     603 .. 0.80

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 5.5
                 HHHHHT-HHHHHHHHHHHHHHHTTS-TTS---HHHHHHHHHHHHHHH CS
     DUF3856  18 kqleegayeeaaasyrkalevsrtipaeeafdheGfdalchaglsea 64 
                 k+ ++++ e+ a++++ a e  +t   e++ +    d  +  +lse 
  EEA19173.1  78 KEKKKAEEEKKAQEAKVAAEEVKTAKVEDVDELPEVDESTVDSLSEE 124
                 44445555556777777777777777777665555555555555554 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.51
                 HHHHHHHHHHHHHHTT-HHHHHHHHHH CS
     DUF3856  99 WiaavfsravaleelGrkdealkafrm 125
                 +++a+ +ra a+e l ++d+al  f  
  EEA19173.1 196 YLKALNRRAIAYEHLEQYDNALLDFTA 222
                 567778888888888888888887765 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.76
                 HHT-HHHHHHHHHHHHHHH CS
     DUF3856  21 eegayeeaaasyrkalevs 39 
                 + + y+eaa+ ++kale+ 
  EEA19173.1 308 TGEGYDEAAQAFEKALELG 326
                 4556777777777777764 PP

  == domain 4  score: -0.2 bits;  conditional E-value: 1.5
                 T-HHHHHHHHHHHHHHH CS
     DUF3856  23 gayeeaaasyrkalevs 39 
                 g+++eaa++y+k++++ 
  EEA19173.1 418 GEFAEAAKDYQKSIDLD 434
                 67777777777777654 PP

  == domain 5  score: -1.1 bits;  conditional E-value: 3
                 HHHT-HHHHHHHHHHHHHH.H CS
     DUF3856  20 leegayeeaaasyrkalev.s 39 
                 l ++ y+ a +++ ka+e+ s
  EEA19173.1 483 LDQQDYQGAIEKFDKAVEMeS 503
                 666677777777777777633 PP

  == domain 6  score: 7.5 bits;  conditional E-value: 0.0066
                 HHHHHHHHHHH--TTSTHHHHHHHHHH CS
     DUF3856  78 adkalryfnrrGeleqdeGklWiaavf 104
                 +++al+yf r  el + eG+   a+ +
  EEA19173.1 563 VAEALKYFTRAAELARTEGEVINAISY 589
                 678999****99999999987555444 PP

>> Usp  Universal stress protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   3.1    0.0031       1.9      25     100 ..      43     115 ..      30     121 .. 0.77
   2 ?    0.5   0.0       1.4   8.2e+02      79     128 ..     408     457 ..     310     460 .. 0.66
   3 ?    0.4   0.1       1.4   8.6e+02      14      53 ..     565     604 ..     560     614 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.0031
                 HHHH.CTSEEEEEEEEESSHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCTTCEEEEEEEESSHHHHHHHHHH CS
         Usp  25 laka.rgaelillhvidprasgavsdadeeaeeeeleleeaeleadaakaaaeaggvkvevvveegdpaeeilevae 100
                  a   +g++++ l  ++++ +++ ++++++  + ++e+++ae+e+    +a+ea+++++ev++   +  +e+ ev e
  EEA19173.1  43 IAVVvTGGTVYYLSTSSSSKPQEPAQPKKSKSQRRKEKKKAEEEK----KAQEAKVAAEEVKTAKVEDVDELPEVDE 115
                 555558999999999999999999999999999999999998885....6788888888888888888888877766 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 1.4
                 TCEEEEEEEESSHHHHHHHHHHHTTSSEEEEESCCSSTTTTCSSBHHHHH CS
         Usp  79 gvkvevvveegdpaeeilevaeeedadliVvGsrgrsglsrlllGSvsey 128
                     +++   g+ ae+  ++ +++d d   + s+ + g+ ++ lGSv+++
  EEA19173.1 408 YHRAQLHFILGEFAEAAKDYQKSIDLDPSFIYSHIQLGVTQYKLGSVASA 457
                 44455566667777888888888888888888888888888888888876 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 1.4
                 HHHHHHHHHHHHHHHCTSEEEEEEEEESSHCCCCCCCHHH CS
         Usp  14 eskkAlewAlelakargaelillhvidprasgavsdadee 53 
                 e+ k + +A+ela++ g  + ++   ++ + + + +++ +
  EEA19173.1 565 EALKYFTRAAELARTEGEVINAISYAEATRTQLEVQEKYP 604
                 67788999*******9999999888888887777766655 PP

>> Sel1  Sel1 repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.1     0.064        38      20      33 ..     143     156 ..     135     158 .. 0.87
   2 ?    6.6   0.2     0.022        13      24      36 ..     564     576 ..     556     577 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.064
        Sel1  20 pkDpekAiewyekA 33 
                  kD+++Aie+y kA
  EEA19173.1 143 SKDYNRAIELYGKA 156
                 68**********99 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.022
        Sel1  24 ekAiewyekAAeq 36 
                  +A++++ +AAe+
  EEA19173.1 564 AEALKYFTRAAEL 576
                 69*********97 PP

>> NARP1  NMDA receptor-regulated protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4  13.2       0.4   2.4e+02     403     464 ..      62     121 ..      54     140 .. 0.63
   2 ?   -0.2   0.1      0.62   3.7e+02      26      66 ..     175     215 ..     166     275 .. 0.61
   3 ?    2.6   0.0     0.086        51     205     240 ..     346     381 ..     335     384 .. 0.85
   4 ?    4.9   0.1     0.017       9.9     209     256 ..     387     434 ..     380     464 .. 0.87
   5 ?    2.8   0.1     0.072        43     205     287 ..     485     571 ..     463     586 .. 0.75

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.4
                 T-S-HHHHHHHHHHHHHHHHHHHHHHHHHHHHH--.......-------------S-SSSTT CS
       NARP1 403 aelseaerkklrkkakkaekkaekeeaekaekekekkaaekkakkedeeakkededplgekL 464
                 +  ++a+ kk +++ +k++kkae+e++++++k +++  + k+ak ed ++ +e ++ + ++L
  EEA19173.1  62 KPQEPAQPKKSKSQRRKEKKKAEEEKKAQEAKVAAE--EVKTAKVEDVDELPEVDESTVDSL 121
                 456778888888888888888887777755554443..344555555555444444444444 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.62
                 HHHHHGGG---HHHHHHHHHHHHHHTT-HHHHHHHHHHHHH CS
       NARP1  26 hLeekekqivDklavketkaelllkLgrkeeAeatyeaLle 66 
                  L+e ek + D+ a + + +e+l +L+r++ A + +e+  +
  EEA19173.1 175 VLSEWEKVVEDTSAALVMDSEYLKALNRRAIAYEHLEQYDN 215
                 67777777777777777777887777777776655544333 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.086
                 HT-SHHHHHHHHHHHHH-TT-HHHHHHHHHHHHHTT CS
       NARP1 205 lgsrekAleyidkaiehtptlvelyltKarilkhaG 240
                  g+ + Ale ++k ie +p+l++ y+ +a ++   G
  EEA19173.1 346 RGDAQSALEDLNKSIEIQPSLTQSYIKRASLHLELG 381
                 578899**********************99876655 PP

  == domain 4  score: 4.9 bits;  conditional E-value: 0.017
                 HHHHHHHHHHHHH-TT-HHHHHHHHHHHHHTT-HHHHHHHHHHHHHCT CS
       NARP1 209 ekAleyidkaiehtptlvelyltKarilkhaGdlkkAaevmeearklD 256
                 + A++  ++ai+h+    ++y+ +a+++   G++ +Aa+  +++  lD
  EEA19173.1 387 DGAVDDFEAAIAHNKDDPDIYYHRAQLHFILGEFAEAAKDYQKSIDLD 434
                 56889999******************************9888877777 PP

  == domain 5  score: 2.8 bits;  conditional E-value: 0.072
                 HT-SHHHHHHHHHHHHH-....TT-HHHH..HHHH.HHHHHTT-HHHHHHHHHHHHHCTTT-HHHHHHHHHHHHHTT-HHHHHHHHTTTS CS
       NARP1 205 lgsrekAleyidkaieht....ptlvely..ltKa.rilkhaGdlkkAaevmeearklDlaDRyiNskcakymLradeveeAeetvslFt 287
                  ++++ A+e+ dka+e +    pt++++   ++Ka  i++ + d+k+A ++ ++a  +D +     +  a+ +L++++v+eA +    Ft
  EEA19173.1 485 QQDYQGAIEKFDKAVEMEsktkPTAINVLplINKAlGIFQWKQDFKEAESLCQKALIIDPECDIAVGTMAQLLLQQGKVAEALKY---FT 571
                 4567788888888887533334999998533789845999999999999999999999988777777888999999999998875...44 PP

>> TPR_6  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.2      0.67     4e+02      13      27 ..     140     157 ..     127     158 .. 0.72
   2 ?    0.3   0.1       2.3   1.4e+03       5      20 ..     202     217 ..     198     221 .. 0.85
   3 ?   -0.6   0.0       4.6   2.8e+03      17      29 ..     232     244 ..     230     246 .. 0.88
   4 ?    3.9   0.4      0.16        97      10      28 ..     304     324 ..     295     325 .. 0.69
   5 ?   -0.7   0.0       4.9     3e+03      10      31 ..     344     364 ..     335     365 .. 0.73
   6 ?    3.2   0.0      0.27   1.6e+02       3      31 ..     407     435 ..     405     436 .. 0.82
   7 ?    4.7   0.0     0.096        57       5      30 ..     443     468 ..     439     470 .. 0.89
   8 ?    3.8   0.1      0.18   1.1e+02       6      27 ..     478     499 ..     477     501 .. 0.85
   9 ?    5.1   0.7     0.067        40       6      27 ..     553     574 ..     552     577 .. 0.90

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.67
                 H...HHHHHHHHHHHHHH CS
       TPR_6  13 l...gdtdkAlealerli 27 
                 +   +d+ +A+e++ + i
  EEA19173.1 140 AygsKDYNRAIELYGKAI 157
                 044469********9876 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 2.3
                 HHHHHHHHHHHHHHHH CS
       TPR_6   5 klalsyrklgdtdkAl 20 
                 ++a +y+ l ++d+Al
  EEA19173.1 202 RRAIAYEHLEQYDNAL 217
                 7899****88***997 PP

  == domain 3  score: -0.6 bits;  conditional E-value: 4.6
                 HHHHHHHHHHHHH CS
       TPR_6  17 dkAlealerlike 29 
                 ++++e lerl+k+
  EEA19173.1 232 RQSRESLERLLKK 244
                 5899******997 PP

  == domain 4  score: 3.9 bits;  conditional E-value: 0.16
                 HHH.HH.HHHHHHHHHHHHHH CS
       TPR_6  10 yrk.lg.dtdkAlealerlik 28 
                 +++ +g  +d+A +a+e+ ++
  EEA19173.1 304 MEQkTGeGYDEAAQAFEKALE 324
                 33223559*********9886 PP

  == domain 5  score: -0.7 bits;  conditional E-value: 4.9
                 HHHHHHHHHHHHHHHHHHHH-T CS
       TPR_6  10 yrklgdtdkAlealerlikeYP 31 
                 y+++ d++ Ale l++ i+  P
  EEA19173.1 344 YLRG-DAQSALEDLNKSIEIQP 364
                 4545.88888888888777666 PP

  == domain 6  score: 3.2 bits;  conditional E-value: 0.27
                 HHHHHHHHHHHHHHHHHHHHHHHHHHH-T CS
       TPR_6   3 lyklalsyrklgdtdkAlealerlikeYP 31 
                 +y++a++++ lg+ ++A + +++ i+  P
  EEA19173.1 407 YYHRAQLHFILGEFAEAAKDYQKSIDLDP 435
                 789999999667*********99887766 PP

  == domain 7  score: 4.7 bits;  conditional E-value: 0.096
                 HHHHHHHHHHHHHHHHHHHHHHHHH- CS
       TPR_6   5 klalsyrklgdtdkAlealerlikeY 30 
                 +l+  ++klg  + A+++++r +k++
  EEA19173.1 443 QLGVTQYKLGSVASAMATFKRSVKKF 468
                 79******99***********99987 PP

  == domain 8  score: 3.8 bits;  conditional E-value: 0.18
                 HHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   6 lalsyrklgdtdkAlealerli 27 
                  +++++ ++d++ A+e +++ +
  EEA19173.1 478 YGELLLDQQDYQGAIEKFDKAV 499
                 688889878*********9987 PP

  == domain 9  score: 5.1 bits;  conditional E-value: 0.067
                 HHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   6 lalsyrklgdtdkAlealerli 27 
                 +a++++++g+ ++Al+++ r  
  EEA19173.1 553 MAQLLLQQGKVAEALKYFTRAA 574
                 79999999**********9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (624 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2518  (0.140443); expected 358.6 (0.02)
Passed bias filter:                     1235  (0.0688828); expected 358.6 (0.02)
Passed Vit filter:                       202  (0.0112667); expected 17.9 (0.001)
Passed Fwd filter:                        34  (0.00189637); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              30  [number of targets reported over threshold]
# CPU time: 0.98u 0.37s 00:00:01.35 Elapsed: 00:00:00.56
# Mc/sec: 3379.59
//
Query:       EEA19174.1  [L=322]
Description: acyl-protein thioesterase 1,2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-21   77.4   0.8    1.2e-09   38.3   0.0    4.0  4  Abhydrolase_2  Phospholipase/Carboxylesterase
  ------ inclusion threshold ------
      0.075   12.5   0.0       0.17   11.4   0.0    1.6  1  Peptidase_S9   Prolyl oligopeptidase family
       0.11   11.8   0.0       0.23   10.7   0.0    1.6  1  Hydrolase_4    Serine aminopeptidase, S33


Domain annotation for each model (and alignments):
>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.0   0.0    0.0031        19       5      30 ..      14      39 ..      11      51 .. 0.82
   2 !    7.7   0.1   0.00047       2.8      37      69 ..      76     108 ..      65     130 .. 0.81
   3 !   38.3   0.0   2.1e-13   1.2e-09      83     149 ..     145     213 ..     132     219 .. 0.91
   4 !   22.1   0.0   1.9e-08   0.00011     151     214 ..     253     318 ..     236     321 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0031
                   EEE--SS---EEEEEE--TT--SHHH CS
  Abhydrolase_2  5 evvspkdkaqavviflHGlGdsghaw 30
                   ++  ++++++++ i+lH  G+++  +
     EEA19174.1 14 VINPQSSPHKQTFILLHDRGSNATDF 39
                   5777899**********999998554 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.00047
                    TT--TTEEEEEE---EEE-GGGTT-EEE-SS-B CS
  Abhydrolase_2  37 eaalpnikfifphgpelpvtlnggmrmpaWfdl 69 
                      a+p+ kf+fp ++ l        +  +Wfd 
     EEA19174.1  76 HTAFPHAKFVFPTASMLRAATFTESVINQWFDT 108
                    6799************777777777799***96 PP

  == domain 3  score: 38.3 bits;  conditional E-value: 2.1e-13
                    HHHHHHHHHHHHHHHHHTT.--GGGEEEEEETHHHHHHHHHHHT-SS.--SEEEEES---TTGGGTTTT CS
  Abhydrolase_2  83 ikksaekleelidaelkkg.ipssriiigGFSqGaalalylaltlpk.klggivafsgalplsqkless 149
                      ++a++++eli+ae++    ++  +iigGFSqG a +l +al      lgg +++sg++p +++++++
     EEA19174.1 145 LRDTARYIHELIKAEIEILnGDAGSVIIGGFSQGSAASLISALLWDGdLLGGWIGLSGWMPFAEEVMDA 213
                    67899************987899*******************99988799************9999875 PP

  == domain 4  score: 22.1 bits;  conditional E-value: 1.9e-08
                    -GGGGG-EEEEEEETT-SSS-HHHHHHHHHHHHTTS-...GEEEEEETT--SS--HHHHHHHHHHHH CS
  Abhydrolase_2 151 tavtkklpilqiHgeeDpvvplalgkaakevlkkllk...kvelksyeglaHsideeemqdikeflk 214
                    + ++  +p ++ Hg+eD++v l lg ++   l++l     + + k y gl H  +e  + d+ efl 
     EEA19174.1 253 SSLN-GIPLFLAHGSEDKTVHLTLGRQMVDCLESLGWsnhNIQWKEYSGLTHTYSESILSDMVEFLT 318
                    4444.69*************************998655569999*********************96 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   2.8e-05      0.17     142     205 ..     256     317 ..     204     321 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 2.8e-05
                   ---EEEEEEETT-SSS-THHHHHHHHHHH...--S-SEEEEEETTS-SSTTSSHHHHHHHHHHHHHH CS
  Peptidase_S9 142 aypplLlihGlaDdrvppaealklvaaLq...kkgknvlllifpdegHgvgkprakveelarllaFl 205
                   +  pl+l hG +D+ v++  + ++v+ L+     ++n++++ + +  H     +++   l ++++Fl
    EEA19174.1 256 NGIPLFLAHGSEDKTVHLTLGRQMVDCLEslgWSNHNIQWKEYSGLTH-----TYSESILSDMVEFL 317
                   5679*************************5544455577777777777.....55566666666666 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   3.9e-05      0.23     182     232 ..     248     303 ..     200     306 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 3.9e-05
  Hydrolase_4 182 rleeraakitlPllllhGeaDkvvdpeasrelyerlgsk.....dktlklypglyH 232
                  +++++ +   +Pl+l hG++Dk v+    r++++ l s      + + k y gl H
   EEA19174.1 248 DATDQSSLNGIPLFLAHGSEDKTVHLTLGRQMVDCLESLgwsnhNIQWKEYSGLTH 303
                  3334444444***********************99987543334666667777777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (322 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       420  (0.0234257); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.40
# Mc/sec: 2389.65
//
Query:       EEA19175.1  [L=322]
Description: acyl-protein thioesterase 1,2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-21   77.4   0.8    1.2e-09   38.3   0.0    4.0  4  Abhydrolase_2  Phospholipase/Carboxylesterase
  ------ inclusion threshold ------
      0.075   12.5   0.0       0.17   11.4   0.0    1.6  1  Peptidase_S9   Prolyl oligopeptidase family
       0.11   11.8   0.0       0.23   10.7   0.0    1.6  1  Hydrolase_4    Serine aminopeptidase, S33


Domain annotation for each model (and alignments):
>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.0   0.0    0.0031        19       5      30 ..      14      39 ..      11      51 .. 0.82
   2 !    7.7   0.1   0.00047       2.8      37      69 ..      76     108 ..      65     130 .. 0.81
   3 !   38.3   0.0   2.1e-13   1.2e-09      83     149 ..     145     213 ..     132     219 .. 0.91
   4 !   22.1   0.0   1.9e-08   0.00011     151     214 ..     253     318 ..     236     321 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0031
                   EEE--SS---EEEEEE--TT--SHHH CS
  Abhydrolase_2  5 evvspkdkaqavviflHGlGdsghaw 30
                   ++  ++++++++ i+lH  G+++  +
     EEA19175.1 14 VINPQSSPHKQTFILLHDRGSNATDF 39
                   5777899**********999998554 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.00047
                    TT--TTEEEEEE---EEE-GGGTT-EEE-SS-B CS
  Abhydrolase_2  37 eaalpnikfifphgpelpvtlnggmrmpaWfdl 69 
                      a+p+ kf+fp ++ l        +  +Wfd 
     EEA19175.1  76 HTAFPHAKFVFPTASMLRAATFTESVINQWFDT 108
                    6799************777777777799***96 PP

  == domain 3  score: 38.3 bits;  conditional E-value: 2.1e-13
                    HHHHHHHHHHHHHHHHHTT.--GGGEEEEEETHHHHHHHHHHHT-SS.--SEEEEES---TTGGGTTTT CS
  Abhydrolase_2  83 ikksaekleelidaelkkg.ipssriiigGFSqGaalalylaltlpk.klggivafsgalplsqkless 149
                      ++a++++eli+ae++    ++  +iigGFSqG a +l +al      lgg +++sg++p +++++++
     EEA19175.1 145 LRDTARYIHELIKAEIEILnGDAGSVIIGGFSQGSAASLISALLWDGdLLGGWIGLSGWMPFAEEVMDA 213
                    67899************987899*******************99988799************9999875 PP

  == domain 4  score: 22.1 bits;  conditional E-value: 1.9e-08
                    -GGGGG-EEEEEEETT-SSS-HHHHHHHHHHHHTTS-...GEEEEEETT--SS--HHHHHHHHHHHH CS
  Abhydrolase_2 151 tavtkklpilqiHgeeDpvvplalgkaakevlkkllk...kvelksyeglaHsideeemqdikeflk 214
                    + ++  +p ++ Hg+eD++v l lg ++   l++l     + + k y gl H  +e  + d+ efl 
     EEA19175.1 253 SSLN-GIPLFLAHGSEDKTVHLTLGRQMVDCLESLGWsnhNIQWKEYSGLTHTYSESILSDMVEFLT 318
                    4444.69*************************998655569999*********************96 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   2.8e-05      0.17     142     205 ..     256     317 ..     204     321 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 2.8e-05
                   ---EEEEEEETT-SSS-THHHHHHHHHHH...--S-SEEEEEETTS-SSTTSSHHHHHHHHHHHHHH CS
  Peptidase_S9 142 aypplLlihGlaDdrvppaealklvaaLq...kkgknvlllifpdegHgvgkprakveelarllaFl 205
                   +  pl+l hG +D+ v++  + ++v+ L+     ++n++++ + +  H     +++   l ++++Fl
    EEA19175.1 256 NGIPLFLAHGSEDKTVHLTLGRQMVDCLEslgWSNHNIQWKEYSGLTH-----TYSESILSDMVEFL 317
                   5679*************************5544455577777777777.....55566666666666 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   3.9e-05      0.23     182     232 ..     248     303 ..     200     306 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 3.9e-05
  Hydrolase_4 182 rleeraakitlPllllhGeaDkvvdpeasrelyerlgsk.....dktlklypglyH 232
                  +++++ +   +Pl+l hG++Dk v+    r++++ l s      + + k y gl H
   EEA19175.1 248 DATDQSSLNGIPLFLAHGSEDKTVHLTLGRQMVDCLESLgwsnhNIQWKEYSGLTH 303
                  3334444444***********************99987543334666667777777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (322 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       420  (0.0234257); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.26s 00:00:00.81 Elapsed: 00:00:00.47
# Mc/sec: 2059.08
//
Query:       EEA19176.1  [L=322]
Description: acyl-protein thioesterase 1,2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-21   77.4   0.8    1.2e-09   38.3   0.0    4.0  4  Abhydrolase_2  Phospholipase/Carboxylesterase
  ------ inclusion threshold ------
      0.075   12.5   0.0       0.17   11.4   0.0    1.6  1  Peptidase_S9   Prolyl oligopeptidase family
       0.11   11.8   0.0       0.23   10.7   0.0    1.6  1  Hydrolase_4    Serine aminopeptidase, S33


Domain annotation for each model (and alignments):
>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.0   0.0    0.0031        19       5      30 ..      14      39 ..      11      51 .. 0.82
   2 !    7.7   0.1   0.00047       2.8      37      69 ..      76     108 ..      65     130 .. 0.81
   3 !   38.3   0.0   2.1e-13   1.2e-09      83     149 ..     145     213 ..     132     219 .. 0.91
   4 !   22.1   0.0   1.9e-08   0.00011     151     214 ..     253     318 ..     236     321 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0031
                   EEE--SS---EEEEEE--TT--SHHH CS
  Abhydrolase_2  5 evvspkdkaqavviflHGlGdsghaw 30
                   ++  ++++++++ i+lH  G+++  +
     EEA19176.1 14 VINPQSSPHKQTFILLHDRGSNATDF 39
                   5777899**********999998554 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.00047
                    TT--TTEEEEEE---EEE-GGGTT-EEE-SS-B CS
  Abhydrolase_2  37 eaalpnikfifphgpelpvtlnggmrmpaWfdl 69 
                      a+p+ kf+fp ++ l        +  +Wfd 
     EEA19176.1  76 HTAFPHAKFVFPTASMLRAATFTESVINQWFDT 108
                    6799************777777777799***96 PP

  == domain 3  score: 38.3 bits;  conditional E-value: 2.1e-13
                    HHHHHHHHHHHHHHHHHTT.--GGGEEEEEETHHHHHHHHHHHT-SS.--SEEEEES---TTGGGTTTT CS
  Abhydrolase_2  83 ikksaekleelidaelkkg.ipssriiigGFSqGaalalylaltlpk.klggivafsgalplsqkless 149
                      ++a++++eli+ae++    ++  +iigGFSqG a +l +al      lgg +++sg++p +++++++
     EEA19176.1 145 LRDTARYIHELIKAEIEILnGDAGSVIIGGFSQGSAASLISALLWDGdLLGGWIGLSGWMPFAEEVMDA 213
                    67899************987899*******************99988799************9999875 PP

  == domain 4  score: 22.1 bits;  conditional E-value: 1.9e-08
                    -GGGGG-EEEEEEETT-SSS-HHHHHHHHHHHHTTS-...GEEEEEETT--SS--HHHHHHHHHHHH CS
  Abhydrolase_2 151 tavtkklpilqiHgeeDpvvplalgkaakevlkkllk...kvelksyeglaHsideeemqdikeflk 214
                    + ++  +p ++ Hg+eD++v l lg ++   l++l     + + k y gl H  +e  + d+ efl 
     EEA19176.1 253 SSLN-GIPLFLAHGSEDKTVHLTLGRQMVDCLESLGWsnhNIQWKEYSGLTHTYSESILSDMVEFLT 318
                    4444.69*************************998655569999*********************96 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   2.8e-05      0.17     142     205 ..     256     317 ..     204     321 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 2.8e-05
                   ---EEEEEEETT-SSS-THHHHHHHHHHH...--S-SEEEEEETTS-SSTTSSHHHHHHHHHHHHHH CS
  Peptidase_S9 142 aypplLlihGlaDdrvppaealklvaaLq...kkgknvlllifpdegHgvgkprakveelarllaFl 205
                   +  pl+l hG +D+ v++  + ++v+ L+     ++n++++ + +  H     +++   l ++++Fl
    EEA19176.1 256 NGIPLFLAHGSEDKTVHLTLGRQMVDCLEslgWSNHNIQWKEYSGLTH-----TYSESILSDMVEFL 317
                   5679*************************5544455577777777777.....55566666666666 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   3.9e-05      0.23     182     232 ..     248     303 ..     200     306 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 3.9e-05
  Hydrolase_4 182 rleeraakitlPllllhGeaDkvvdpeasrelyerlgsk.....dktlklypglyH 232
                  +++++ +   +Pl+l hG++Dk v+    r++++ l s      + + k y gl H
   EEA19176.1 248 DATDQSSLNGIPLFLAHGSEDKTVHLTLGRQMVDCLESLgwsnhNIQWKEYSGLTH 303
                  3334444444***********************99987543334666667777777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (322 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       420  (0.0234257); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2152.13
//
Query:       EEA19177.1  [L=447]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.3e-16   59.9  22.4    3.3e-16   59.9  22.4    1.7  2  FA_desaturase  Fatty acid desaturase


Domain annotation for each model (and alignments):
>> FA_desaturase  Fatty acid desaturase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.4     0.024   4.2e+02      78     173 ..      76     166 ..      71     169 .. 0.64
   2 !   59.9  22.4   1.8e-20   3.3e-16      11     239 ..     160     374 ..     151     384 .. 0.79

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.024
  FA_desaturase  78 Dpdlaplalsrfeglfryllrlllgllvlgwllalvlglwlrrlarrrapsksrrrkwrllawlllllawlglwlalllllglalllwlvplllll 173
                    Dp+  +++++ f ++   +lr  l+++ ++ +l +++++++r++++  + +      + ll+    ++++++l+  + + +g++   w+++  +++
     EEA19177.1  76 DPSNSSFEPTVFVTFDTSYLRTKLHPYIYNNILVPYIAFARRIVRVDTDVVML-T--HLLLYFSTSVPSAILLYRHFTYIHGVL--HWVMQSYYVG 166
                    77777777777777777888888888888866666666444444444443333.3..667777777777788888888888777..6666665554 PP

  == domain 2  score: 59.9 bits;  conditional E-value: 1.8e-20
  FA_desaturase  11 llglfllgitg.slaHeaaH..galfkkrklnrwlndllgallglplgisysawrisHlrHHay.tngpdeDpdlaplal.srfeglfryllrlll 101
                    +  +   g  +  ++H ++H  g l+k+++  + ++ ++ +++  ++g ++ +++++H++HH+   ngp +D ++    +  +   +++y+lr+++
     EEA19177.1 160 MQSYY-VGT-YtLMMHQHIHmgGILTKSNPFIHAFDVVFPYITNPLMGHTWNSYYYHHIKHHHVeGNGP-DDLSSTIRYQrDSIPDFAHYVLRFMF 252
                    33333.444.449*******877***********************************66666647777.666665433369************** PP

  FA_desaturase 102 gllvlgwllalvlglwlrrlarrrapsksrrrkwrllawlllllawlglwlalllllglalllwlvplllllfllalvlnyveHyggdwgerqvet 197
                    +++             l+++++ ++    ++ +w + +   +++     ++ ++ + + ++ ++l+pl++l + l++  n+ +H+   ++e++  +
     EEA19177.1 253 LVWIEL---------PLYFFRHGKYLLGLKALFWEVGTYISIAA-----LYRYVDARATVF-VFLLPLCMLRIGLMVG-NWGQHAL-VDEEDPTSD 331
                    ****99.........99999999999998865555554444444.....333333333333.9*************99.*****95.777777777 PP

  FA_desaturase 198 sasir.saswllnlltgnlnyHieHHlfPgvpwyrLpelhrrl 239
                     +s+   +   +n +++n +yH+ HHl P+ +w   p+++ r 
     EEA19177.1 332 LRSSItLIDVASNRFCFNDGYHTSHHLNPRRHWRDHPAAFMRA 374
                    7777779*******************************98444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (447 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       718  (0.0400469); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 2947.37
//
Query:       EEA19178.1  [L=720]
Description: Golgi transport protein Sly1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.2e-126  424.3   0.0   1.4e-126  424.1   0.0    1.0  1  Sec1      Sec1 family
  ------ inclusion threshold ------
      0.083   13.3   0.0       0.18   12.2   0.0    1.5  1  HCV_core  Hepatitis C virus core protein
        0.3   11.1   1.7       0.52   10.3   1.0    1.7  2  DUF1043   Protein of unknown function (DUF1043)


Domain annotation for each model (and alignments):
>> Sec1  Sec1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  424.1   0.0  2.3e-130  1.4e-126       1     573 [.      58     709 ..      58     711 .. 0.88

  Alignments for each domain:
  == domain 1  score: 424.1 bits;  conditional E-value: 2.3e-130
                 EEEEE-HHHHHHHHTT--HHHHHTTTEE...ETT..T--S-.....BTTSEEEEEE-S-HHHHHHHHHHHHSS-SBS-EEEEESS---HHHHHHHHH.. CS
        Sec1   1 KvLvlDkelskilssvlkvsdlleegVt...kieklkkrepskrealphlkaiyflrptkenidrlakdfisarrykeyhifftprlseslleglakad 96 
                 KvLv+D++ ++++ssvl+v+dl+  gVt   +i+  + r p     +p+++++y+++pt+ n +++ +d  s+  y+ ++++f+++++++lle++a+++
  EEA19178.1  58 KVLVFDNKGRDVISSVLRVNDLRAWGVTihlNIN--SARYP-----IPDVPVVYLVEPTAVNAQLITSDL-SRGLYSPAYVNFLSSVPRQLLEDFASQI 148
                 9**********************88***644444..25666.....*********************765.6699******************888766 PP

                 S.G.....GGGEEEEE----SEEEETTEEE-STTHHHHSTTG.....GG.......--HHHHHHHHHHHHHHH-..--EEEE.-TT-HHHHHHHH.... CS
        Sec1  97 e.e....vvkkvklkelnldfvplesdlfslnpelplsfrdlyldndnsaleeeieslldriakgLlsvllslekkiPiiry.kgsaasmvakkladel 189
                   +     + +v+  +++l+f++ e+dlfsl   ++++++     n++++ +e++++++d+i++gL+ v +++ + iPiir+ kg aa+ +a kl+++l
  EEA19178.1 149 AtSgtaeHIAQVF--DQYLNFIVAEPDLFSLGLGNDSYWKI----NSAQTSDEDLDNIVDQIVSGLFDVSVTM-GSIPIIRCpKGGAAELIATKLDRKL 240
                 3236666888888..****************7446666653....334456788*******************.89*********************** PP

                 .......HHHHTTT.......--SS--EEEEE-GGG-SSTTTS---BHHHHHHHHS--BTEEEEEE--SS........SEEEEEE--TT..-TTHHHHT CS
        Sec1 190 kekids.kknfese.......ssrqrpvLiIlDRsvDlvtpllhqwTYqaliddllgglnnnnvvleeep........keekeaelvesssDeffaelr 272
                 +++i + k+n +s         +++rpv+iI+DR+vDlv++l h wTYq+l+ d+l+  +++n++++e+          ++k+a++++  +D+f++++ 
  EEA19178.1 241 RDHILNsKDNLFSGnkrpgvaVPSSRPVMIIVDRNVDLVPMLSHGWTYQSLVQDVLK--MHLNRITVETLvdesdpskGKTKKAYDLNA-TDFFWKRNA 336
                 ******77777777******************************************9..899999999889999***888889999888.********* PP

                 TSBHHHHHHHHHHHHHHHHHHH.HTTT....-..........TTHHHHHHHHHH-GGGHHHHHHHHHHHHHHHHHHHHS-HHH.HHHHHHHHHHHHSS- CS
        Sec1 273 hlnfgevgeklkkeakeyqeen.ekkrn.gak..........esiadlkkfvaklpelqeekkklskHtnlaeellkevkkrkldellelEqdlatges 359
                 + +f++v+e++++e+ +y+e++ +++++ ga+          +s  +lk +++ lpel+e+k++l++H+n+a++ll+ +k+r+ld++++lE+++  g  
  EEA19178.1 337 NVPFPQVAEDIDAELTRYKEDAnDITKKtGASsiedlqndtsASAHHLKAAITLLPELRERKATLDMHMNIATALLQGIKDRQLDNFFQLEENI--G-- 431
                 **********************999999877799999999999999999*********************************************..3.. PP

                 -.B--..-HHHHHHHH.-TTS-H.HHHHHHHHHHHH....-B.-HT--GG....GGHHHH.G...GGGG........---.BGGG-------....... CS
        Sec1 360 dkkikekkvieeliad.deptseledklRLlllyslv.egglkekelkellrelvqsaly.g...leylktlrsleklgllkkrkgkksskkkss.... 448
                 + ++k  ++i+eli+d +++t++  dklRL+++++l+ e  l   e+++++++l ++  + +   ++y+k++r++++++++++++g+ ++++  s    
  EEA19178.1 432 K-QSK--AQILELINDsSKGTDP-SDKLRLFIIWFLTtEMELTRGEMTNFEEALQKAG-NeDtssIAYVKRVREITRMTMMTSSTGAPQQQS--Sdlfk 523
                 3.444..4599*****5444555.8************988887779999988777744.432556************999966666444444..35699 PP

                 ......---------S...........TT-----H.....HHHHHHHHTTT-S-TTTS-BSS-GGGS----....................-------- CS
        Sec1 449 ..lklikeeedeesnyd........lsgvsryaPl.....lvrlvealikgkklssespslskkdpsqees....................ssslrsak 512
                   ++l+++ +d+ +           +sgv++++P      l++++e++++ ++++s+s   +++++ ++++                     + ++ ++
  EEA19178.1 524 gfSSLSNRLTDRITSGAlganfdslISGVKNFLPVnkdltLTKITESIMD-PQSASSSAIAKTENYLYFDPrsanargamptssaargqqqAGAGSAST 621
                 998888888888888779999*****************************.999999999*************************99999766666777 PP

                 --------------S-EEEEEEEEEE-HHHHHHHHHHT...T............................SSSEEEEEEEEE--HHHHH CS
        Sec1 513 ktnsaskesaekkkkqrviVffvGGvTysEiralrllskqek............................knkeiiigttsilnpksfl 573
                 ++ +as +++++ +++ +iVf vGG++++E+ +l+++ ++++                            + k++++g+t+++n+++fl
  EEA19178.1 622 PGIAASFGQRRQAFNE-AIVFTVGGGSMEEYGNLQDWVARTSgqpgttgagggpggaaaagtsittsagtHRKRVVYGSTELMNASDFL 709
                 7777777777776666.******************999888899999999999999999999999999977789**************8 PP

>> HCV_core  Hepatitis C virus core protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0     3e-05      0.18       3      47 ..     196     244 ..     194     256 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 3e-05
    HCV_core   3 nlgkvidtltcgfadl...mgyiplvgaplggaaralahgv.rvledgv 47 
                 +l  ++d +  g+ d+   mg ip++ +p ggaa  +a  + r l d +
  EEA19178.1 196 DLDNIVDQIVSGLFDVsvtMGSIPIIRCPKGGAAELIATKLdRKLRDHI 244
                 5778999999999986666***************999876536666665 PP

>> DUF1043  Protein of unknown function (DUF1043)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0       2.2   1.3e+04      66      81 ..     238     253 ..     236     257 .. 0.74
   2 ?   10.3   1.0   8.7e-05      0.52      36     104 ..     369     445 ..     350     453 .. 0.78

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 2.2
     DUF1043  66 qkLyqhlaksseeLlp 81 
                 +kL +h+ +s+++L++
  EEA19178.1 238 RKLRDHILNSKDNLFS 253
                 5788888888888876 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 8.7e-05
     DUF1043  36 akaeleeqkqeledHfaqsaelLetlaedyqkLyqhlaksseeLlp.eleeqelfqqkkleekkaeaee.......e 104
                 + + l++     ++H++ + +lL +l e+  +L  h++  +  L   + ++ ++f+q + +  k+++++       +
  EEA19178.1 369 SIEDLQNDTSASAHHLKAAITLLPELRERKATLDMHMNIATALLQGiKDRQLDNFFQLEENIGKQSKAQilelindS 445
                 55666666777789*************************9999988999*******988888877776655555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (720 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       542  (0.0302304); expected 358.6 (0.02)
Passed bias filter:                      403  (0.0224776); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.67u 0.32s 00:00:00.99 Elapsed: 00:00:00.48
# Mc/sec: 4508.95
//
Query:       EEA19179.1  [L=1198]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    6.4e-06   26.0   3.7    1.1e-05   25.3   3.7    1.4  1  zf_CCCH_4  Zinc finger domain
     0.0084   15.6   0.4      0.016   14.7   0.4    1.4  1  14-3-3     14-3-3 protein
  ------ inclusion threshold ------
       0.01   16.5   0.1      0.041   14.6   0.1    2.0  1  Torus      Torus domain
      0.011   15.5   1.9      0.017   14.9   1.9    1.3  1  zf-CCCH_4  CCCH-type zinc finger
      0.019   15.2   0.2      0.059   13.6   0.2    1.8  1  zf-CCCH_3  Zinc-finger containing family
      0.035   14.0   1.1      0.055   13.4   1.1    1.3  1  zf-CCCH    Zinc finger C-x8-C-x5-C-x3-H type (and similar)
       0.13   12.7   1.3       0.23   12.0   1.3    1.4  1  zf-CCCH_2  RNA-binding, Nab2-type zinc finger
        0.5   10.3   3.5       0.24   11.3   0.1    2.3  2  CedA       Cell division activator CedA
       0.54   10.3   6.2        2.3    8.4   6.2    2.2  1  AT_hook    AT hook motif


Domain annotation for each model (and alignments):
>> zf_CCCH_4  Zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.3   3.7   5.5e-09   1.1e-05       1      19 []    1174    1192 ..    1174    1192 .. 1.00

  Alignments for each domain:
  == domain 1  score: 25.3 bits;  conditional E-value: 5.5e-09
   zf_CCCH_4    1 CkfflqGtCkkGdkCrFaH 19  
                  C+f+ +G+C kG+ C+F+H
  EEA19179.1 1174 CRFWREGKCLKGEDCTFRH 1192
                  ******************* PP

>> 14-3-3  14-3-3 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.4   8.1e-06     0.016      31      95 ..     406     468 ..     389     480 .. 0.72

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 8.1e-06
                 CHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      14-3-3  31 eernlLsvayKnvvgarRaswrvlssieqkeeskeekkvelikeyrekiekeLkeiceevlelld 95 
                 e+ +   va+K vv++ R +w+ ls++ ++ e++  ++ ++++e+r+k+ ++ k i   + + +d
  EEA19179.1 406 EKIKNALVAFKDVVKTVRDEWKSLSQAMKDAENQ--NNNDKASELRNKVVEQRKLINAVITTAID 468
                 55555669*****************975444443..46678888888887765555555555555 PP

>> Torus  Torus domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.1   2.1e-05     0.041      65      92 ..    1166    1193 ..    1140    1196 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 2.1e-05
                  HHSTT--B-HHHHHT--SSGGG-SSB-S CS
       Torus   65 dkekesyfClfFarGlCakGkkCeylHr 92  
                  + +++s+ C f+  G C kG++C++ H+
  EEA19179.1 1166 HPRAGSVACRFWREGKCLKGEDCTFRHD 1193
                  4456789********************6 PP

>> zf-CCCH_4  CCCH-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   1.9   8.6e-06     0.017       3      22 .]    1174    1193 ..    1172    1193 .. 0.97

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 8.6e-06
   zf-CCCH_4    3 CpyfakGsCrfGdnCrFsHd 22  
                  C+++ +G+C  G+ C+F+Hd
  EEA19179.1 1174 CRFWREGKCLKGEDCTFRHD 1193
                  *******************9 PP

>> zf-CCCH_3  Zinc-finger containing family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.2     3e-05     0.059       8      28 ..    1174    1194 ..    1168    1197 .. 0.58

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 3e-05
   zf-CCCH_3    8 cyffyystctkGdscpfrhee 28  
                  c f+   +c kG+ c+frh +
  EEA19179.1 1174 CRFWREGKCLKGEDCTFRHDP 1194
                  555555556666666666655 PP

>> zf-CCCH  Zinc finger C-x8-C-x5-C-x3-H type (and similar)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   1.1   2.8e-05     0.055       4      26 ..    1172    1193 ..    1170    1194 .. 0.91

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 2.8e-05
                  HCBCHHHHHS--TTGGG-SSBSC CS
     zf-CCCH    4 elCrffmrtGyCkyGdrCkFaHg 26  
                  + Crf+++ G C  G+ C F H+
  EEA19179.1 1172 VACRFWRE-GKCLKGEDCTFRHD 1193
                  68******.***********997 PP

>> zf-CCCH_2  RNA-binding, Nab2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   1.3   0.00011      0.23       2      17 ..    1174    1192 ..    1173    1192 .. 0.97

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00011
   zf-CCCH_2    2 Crffpn..C.tnpkCpFaH 17  
                  Crf+    C ++++C+F+H
  EEA19179.1 1174 CRFWREgkClKGEDCTFRH 1192
                  ******************* PP

>> CedA  Cell division activator CedA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   0.00012      0.24      15      43 ..     375     403 ..     371     412 .. 0.92
   2 ?   -3.5   0.7       4.9   9.7e+03       3      20 ..    1072    1089 ..    1071    1097 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00012
        CedA  15 vprvepappehavkmeeyrdvwvlknkyv 43 
                 +p v pa pe av+ +  + +w  +nky 
  EEA19179.1 375 LPEVRPADPEGAVQYDTIKAIWSPRNKYP 403
                 799************************95 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 4.9
        CedA    3 plrqqnrpvisyvprvep 20  
                   + qq++pv   +p+  p
  EEA19179.1 1072 QMAQQQQPVAPQMPQAPP 1089
                  678999999877776555 PP

>> AT_hook  AT hook motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   6.2    0.0011       2.3       1      11 [.     333     343 ..     333     345 .. 0.88

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0011
     AT_hook   1 kRkRGRPrKaa 11 
                 ++kRGRPrK++
  EEA19179.1 333 PKKRGRPRKHP 343
                 79*******86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1198 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1241  (0.0692175); expected 358.6 (0.02)
Passed bias filter:                      515  (0.0287244); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.98u 0.31s 00:00:01.29 Elapsed: 00:00:00.48
# Mc/sec: 7497.86
//
Query:       EEA19180.1  [L=263]
Description: DUF218 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.8e-06   25.8   0.0    1.4e-05   25.1   0.0    1.3  1  DUF218    DUF218 domain


Domain annotation for each model (and alignments):
>> DUF218  DUF218 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1   0.0   7.9e-10   1.4e-05      11      98 ..      45     158 ..      12     178 .. 0.76

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 7.9e-10
      DUF218  11 pllaeRldeaaelyrag....kiivsGg...gadedvseaeamaeylrelgvp.eea...........illedrsrnTeenarfskell........ke 82 
                 p++ + ++++++ y++      +++sGg    ++++ +e e + +++r++++  +++           il e+++++ ++n++fs  l           
  EEA19180.1  45 PTFVNHVKAGLREYEKSgnsgVLVFSGGatkRGKTSLTEGESYLNLARDNNFFlSNHqqvsanidttnILAETHATDSYQNILFSLLLYrqhtqlayP- 142
                 7777889999999988877666*******974458999999988888885532222234555556666*****************9999******642. PP

      DUF218  83 rsillVTsafHmpRal 98 
                 +s+ ++T+af  +R l
  EEA19180.1 143 KSVTIITHAFKRRRFL 158
                 49********999975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (263 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       419  (0.02337); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 1870.74
//
Query:       EEA19181.1  [L=232]
Description: mitotic spindle checkpoint protein (Mad2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-33  116.4   0.0    1.5e-33  116.2   0.0    1.0  1  HORMA          HORMA domain
  ------ inclusion threshold ------
      0.018   14.5   1.9      0.031   13.7   1.9    1.3  1  DUF3530        Protein of unknown function (DUF3530)
      0.022   14.3   0.1      0.031   13.8   0.1    1.2  1  Peptidase_C13  Peptidase C13 family
      0.045   14.2   0.0       0.15   12.5   0.0    2.0  1  DUF2660        Protein of unknown function (DUF2660)
      0.081   13.0   0.0         11    6.2   0.0    2.2  2  Arcadin_1      Arcadin 1


Domain annotation for each model (and alignments):
>> HORMA  HORMA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.2   0.0   4.1e-37   1.5e-33       1     212 []      18     220 ..      18     220 .. 0.86

  Alignments for each domain:
  == domain 1  score: 116.2 bits;  conditional E-value: 4.1e-37
       HORMA   1 SlelvkellaasissilylRglfpedaFedrklsglklkiLlrgsseeadrlldwLekGvfdaLe....kkyLealiltIykdkdepenvlEsYtFsfk 95 
                 S +lv e++++si+sily+Rg++p+++F+ +k+  + l++L+ ++    d++ ++++k ++++L+     +++++l+++I++++  +  ++E+++F+++
  EEA19181.1  18 SSKLVAEFFEYSINSILYQRGVYPAEDFSPVKK--YGLNMLVSSD----DQVRAYIKK-IMSQLNkwmiGGKISKLVVVITSKETGE--HVERWQFDVQ 107
                 889*****************************9..9*****8888....9******99.*****988889***********555553..9********* PP

       HORMA  96 ytksggkedvssskletkkknleslsldek......eeekkktekevkkelealirrlitltqsLpplpekryltmkLlytdd....tPedyePpgFka 184
                 ++k++  + +++s++++ k+n+++   d +      e + +kte ++++e++a++r++++++++Lp+l+   ++t+++l+++d    +P ++       
  EEA19181.1 108 IFKQAAAAGRKKSSTAD-KENSATAAADREnaaaaeEPTPEKTETQIQQEIQAIFRQITASVTFLPVLD--GNCTFNVLVYADadsdVPVEW------- 196
                 ***88887666666654.44555555555579**99888999**************************9..9***********666666666....... PP

       HORMA 185 aaeeedstrkeneepekvsvGkvdtghh 212
                 ++    s++ke  + ekv++++++t+ h
  EEA19181.1 197 GD----SDAKEITNGEKVQLRSFSTNNH 220
                 33....4569999************988 PP

>> DUF3530  Protein of unknown function (DUF3530)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   1.9   8.8e-06     0.031     135     191 ..     116     171 ..     107     184 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 8.8e-06
     DUF3530 135 srpeysakasettaaveataadkankasekkaptdaearkahrervrarlqaaiafl 191
                  r ++s++ +e++a+++a  +++a+++++++++t++ + ++  + ++ ++ a++ fl
  EEA19181.1 116 GRKKSSTADKENSATAAADRENAAAAEEPTPEKTET-QIQQEIQAIFRQITASVTFL 171
                 466677777777777777777777777777777777.77999************998 PP

>> Peptidase_C13  Peptidase C13 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.1   8.6e-06     0.031     119     233 ..      54     165 ..      48     180 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 8.6e-06
                    TTEEE-SSSSEEEHHHHHHHHHHHHHCT--SEEEEEEESTTGGGGTTTS-TTSSEEEEESS-TTS--BEECE.CTTTTCEEEEHHHHHHHHHHHHS CS
  Peptidase_C13 119 pgvlevpeeddleakdLaeaLkkmhakkkykklviyleaceSgsmfeellkdinvyaltAanadessfgtycedeedgtylgdlfsvawledsdde 214
                    + +++ +++ + + k++++ L+k  + +k +klv+++++ e g  +e  + d +++  +Aa+ +++s  +  ++e+ +t  +d   +a+ e+   e
     EEA19181.1  54 NMLVSSDDQVRAYIKKIMSQLNKWMIGGKISKLVVVITSKETGEHVERWQFDVQIFKQAAAAGRKKSSTA--DKENSATAAADRENAAAAEEPTPE 147
                    5566667777788999********************************999*******999999999888..788888888887777777665553 PP

                    -TTT-BHHHHHHHHHHHHS CS
  Peptidase_C13 215 dlsketlekqfelvkkkva 233
                    ++ ++ ++++ +++ ++++
     EEA19181.1 148 KT-ETQIQQEIQAIFRQIT 165
                    33.3334444444444444 PP

>> DUF2660  Protein of unknown function (DUF2660)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   4.3e-05      0.15      30      76 ..       4      53 ..       1      64 [. 0.85

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 4.3e-05
     DUF2660 30 krkksevkklslkekielswqfl.ydltkiilkk..fskedvvevnkiGs 76
                +++ks+v+klslk   +l   f+ y +  i+ ++  +  ed   v+k G 
  EEA19181.1  4 DKEKSKVHKLSLKGSSKLVAEFFeYSINSILYQRgvYPAEDFSPVKKYGL 53
                689*************9988765499999999986678999999999985 PP

>> Arcadin_1  Arcadin 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0    0.0086        31      40      84 ..      59      95 ..      44     108 .. 0.74
   2 ?    6.2   0.0     0.003        11      40      67 ..     146     173 ..     126     185 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.0086
                ---------------------------.--EEEEEEEEEE-HHHH CS
   Arcadin_1 40 sdeedaeiaRevapivqqivrslpllslnkvkvpritLvlteeEl 84
                s   d ++   + +i++q+ + + +++     + ++++v+t +E 
  EEA19181.1 59 S---DDQVRAYIKKIMSQLNKWMIGGK-----ISKLVVVITSKET 95
                4...56788889999999999998877.....4667777777775 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.003
                 ---------------------------. CS
   Arcadin_1  40 sdeedaeiaRevapivqqivrslpllsl 67 
                 +++++++i+ e++ i +qi  s+ +l++
  EEA19181.1 146 PEKTETQIQQEIQAIFRQITASVTFLPV 173
                 566799*************999888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (232 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1430  (0.079759); expected 358.6 (0.02)
Passed bias filter:                      753  (0.041999); expected 358.6 (0.02)
Passed Vit filter:                        76  (0.00423894); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 1520.14
//
Query:       EEA19182.1  [L=663]
Description: GTP binding protein Guf1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    7.6e-50  169.2   0.0    1.2e-49  168.5   0.0    1.3  1  GTP_EFTU     Elongation factor Tu GTP binding domain
    1.3e-42  144.3   4.0    2.4e-42  143.4   4.0    1.5  1  LepA_C       GTP-binding protein LepA C-terminus
    4.9e-17   61.7   0.0    8.9e-17   60.9   0.0    1.4  1  EFG_C        Elongation factor G C-terminus
    3.1e-06   27.5   0.0      7e-06   26.3   0.0    1.7  1  GTP_EFTU_D2  Elongation factor Tu domain 2
    1.6e-05   24.6   0.0    0.00027   20.6   0.0    2.3  2  Ras          Ras family
      4e-05   23.7   0.0     0.0001   22.4   0.0    1.7  1  MMR_HSR1     50S ribosome-binding GTPase
     0.0077   16.3   0.0      0.017   15.2   0.0    1.6  1  EFG_II       Elongation Factor G, domain II
     0.0093   15.4   0.0      0.022   14.2   0.0    1.6  1  SRPRB        Signal recognition particle receptor beta subuni
  ------ inclusion threshold ------
      0.016   15.1   0.0      0.033   14.0   0.0    1.5  1  RF3_C        Class II release factor RF3, C-terminal domain


Domain annotation for each model (and alignments):
>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  168.5   0.0   5.9e-53   1.2e-49       2     193 ..      66     242 ..      65     243 .. 0.94

  Alignments for each domain:
  == domain 1  score: 168.5 bits;  conditional E-value: 5.9e-53
                 CEEEEEEEESTTSSHHHHHHHHHHHTTSSCHHHHHHHHHSTHCHSHHHHHHTSCSSCEEEEEE..TTCSSEEEEEEEESSSGGGHHHHHHHHHT-SEEE CS
    GTP_EFTU   2 rirnigiighvDhGKtTLtdrLlyktgaiskkgekaeeervlDtlkeErergiTiksaaisle..ketkkylinliDtPGHvdFskevirglrvlDgav 98 
                 r rn++i++hvDhGK+TL+drLl+ tg i+  ++k    +vlD+l+ ErergiT+k++++++   +++++yl++liDtPGHvdF  ev+r+++ + ga+
  EEA19182.1  66 RFRNFCIVAHVDHGKSTLSDRLLELTGVIQPGSNK----QVLDKLDVERERGITVKAQTCTMLynHNGEDYLLHLIDTPGHVDFRAEVSRSYASCGGAL 160
                 78*****************************5554....37*******************999756********************************* PP

                 EEEETTTBSTHHHHHHHHHHHHTTTEEEEEEESCGSTHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTTEEEEEEBTTTTBTHHHHHHHHHHHSH CS
    GTP_EFTU  99 lvvdaveGvepqteevlrlalkegvpiivfiNKmDrlkaelkeiveevkqklsrkeeklekygekgekevpvvfgSalkgegvktllealvellp 193
                 l+vda++Gv++qt  +++la ++g++++ ++NK+D + a+ ++  e++++++        +  ++     + + +Sa++g +v +ll +++e +p
  EEA19182.1 161 LLVDASQGVQAQTVANFYLAFAQGLELVPVLNKVDLPSADPERALEQMRSSF--------ELDTD-----NAIKVSAKTGLNVAQLLPTVIERIP 242
                 ****************************************************........33444.....58*******************9987 PP

>> LepA_C  GTP-binding protein LepA C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  143.4   4.0   1.2e-45   2.4e-42       1     106 [.     556     661 ..     556     662 .. 0.99

  Alignments for each domain:
  == domain 1  score: 143.4 bits;  conditional E-value: 1.2e-45
                 ESSCB-GGG-EEEETTTHHHHHHHHHHHHHHHS---SS-EEEEEEETTEEEEEEEE----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
      LepA_C   1 ingekvdaLslivhrskaeergrklvekLkeliprqlfevaiqaaigskviaretikalrkdvlaklyggditrkkKllekqkegkkrlkkignveipq 99 
                 +n+++vda++ ivh s+ae+ g+++v+k+ke+++rq+fe++iqaa+g+k++aretik++rkdvlakl+++di rk+Kllekqkeg+krl+++gnv i++
  EEA19182.1 556 VNKKSVDAVARIVHYSQAERLGKQWVTKFKEHVDRQMFEIIIQAAVGRKIVARETIKPYRKDVLAKLHAADIGRKRKLLEKQKEGRKRLNAVGNVVIDH 654
                 79************************************************************************************************* PP

                 XXXXXXX CS
      LepA_C 100 eaflavl 106
                 +af+a+l
  EEA19182.1 655 SAFQAFL 661
                 *****99 PP

>> EFG_C  Elongation factor G C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.9   0.0   4.5e-20   8.9e-17       2      86 ..     467     552 ..     466     555 .. 0.95

  Alignments for each domain:
  == domain 1  score: 60.9 bits;  conditional E-value: 4.5e-20
                 EEEEEEEEEEEEECCCCCCHHHHHHHCT-EEEEEEEE.TTEEEEEEEEEGGG-T.THHHCHHHCTTTS-EEEEEEEEEEE--HHHH CS
       EFG_C   2 llEPivkveievpeeyvgkvisdlssrrGeiedmeqdasgrviieaeiPlaeli.gfateLrslTkGegsfsmefsgYeevpgdkl 86 
                 l EP+v ++++ p+ey+gkvi+++++ rG++ + e+ + ++vi+++e+Pl +l+ +f+ +L+  TkG++++++e +g++ ++ +kl
  EEA19182.1 467 LREPYVMATLTFPDEYLGKVIELCEANRGIQHTLEYFTPTQVILKYELPLGQLVeDFFGKLKGSTKGYATLDYEEAGWKVSNIVKL 552
                 78***********************************99****************************************9887765 PP

>> GTP_EFTU_D2  Elongation factor Tu domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.3   0.0   3.5e-09     7e-06       1      74 []     266     338 ..     266     338 .. 0.89

  Alignments for each domain:
  == domain 1  score: 26.3 bits;  conditional E-value: 3.5e-09
                  EEEEEEEEEESEEETTEEEEEECTCTTSEEEEEEEEEEEEETEEESEEETTSEEEE..EEEESSCCSGSSTTCEEE CS
  GTP_EFTU_D2   1 GtvalgrvysGtlkkGdevrilgndtskkeivtrissletfhededeavaganaGv..ivaikgledaiivGdtlt 74 
                  G++ l+rv++G+++ Gd+v+     t+ k  v++++ ++  + ++++++ag+++++  + ++k  ++a ++Gdt+t
   EEA19182.1 266 GVILLVRVFDGEIRAGDQVVS--FATGLKYFVGEVGIMYPDQTPQTTLRAGQVGYIyfNPGMKRSKEA-KIGDTFT 338
                  8899*****************..***9999*********************99876115578888887.9999975 PP

>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.6   0.0   1.3e-07   0.00027      30     160 ..     114     241 ..     102     243 .. 0.79
   2 ?    1.1   0.1      0.13   2.6e+02     105     141 ..     550     587 ..     539     606 .. 0.76

  Alignments for each domain:
  == domain 1  score: 20.6 bits;  conditional E-value: 1.3e-07
                 TTSSEEEEEEEEEETTEEEEEEEEEETTSGGGHHHHHHHHTTESEEEEEEETTBHHHHHTHHHHHHHHHHHSTTTSEEEEEEETTTGGG...G-SS-HH CS
         Ras  30 sTigvdfytkeievdgkevkleiwDTAGqeefkslrelyyrdaegillvyditsresfenvkkwveeikrvaeenvpivLvGnKvDlee...kravste 125
                  T+ ++  t   + +g+++ l++ DT G  +f++  + +y ++ g+ll+ d ++    ++v++++  + +  e    +v v nKvDl +   +ra+++ 
  EEA19182.1 114 ITVKAQTCTMLYNHNGEDYLLHLIDTPGHVDFRAEVSRSYASCGGALLLVDASQGVQAQTVANFYLAFAQGLE----LVPVLNKVDLPSadpERALEQM 208
                 466666666667778***********************************************99988776555....78888*****994444444443 PP

                 HHHHHHHHHT.SEEEEEBTTTTCTHHHHHHHHHHHH CS
         Ras 126 egeelakelg.lkfletSAktnenveeafeellrei 160
                 ++   + el+  + +++SAkt  nv +++ +++++i
  EEA19182.1 209 RS---SFELDtDNAIKVSAKTGLNVAQLLPTVIERI 241
                 33...33333245689************99999876 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.13
                 SEEEEEEETTTGGG.G-SS-HHHHHHHHHHHTSEEEEE CS
         Ras 105 vpivLvGnKvDlee.kravsteegeelakelglkflet 141
                 v++ L+ nK  ++   r v+++++e+l k++ +kf e 
  EEA19182.1 550 VKLQLLVNKKSVDAvARIVHYSQAERLGKQWVTKFKEH 587
                 56667777766665579999999999999999999875 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.4   0.0   5.1e-08    0.0001       3     100 ..      71     177 ..      69     193 .. 0.68

  Alignments for each domain:
  == domain 1  score: 22.4 bits;  conditional E-value: 5.1e-08
                 EEEESTTSSHHHHHHHHHT..............STEEESSSTTSSSSEEEEEEE....ETTEEEEEEECGGCSSHHHHHHHHHHHHHHHHCTSEEEEEE CS
    MMR_HSR1   3 aivGrpNvGKStLinaltg..............ekaivsdkpgtTrdinegrvk....lkgkeielvDtpGliegaseekglgkaflaleeadlillvv 83 
                 +iv +   GKStL  +l++              +k  v+++ g T + ++ ++      ++  ++l+DtpG ++    + ++++++++   +  +ll+v
  EEA19182.1  71 CIVAHVDHGKSTLSDRLLEltgviqpgsnkqvlDKLDVERERGITVKAQTCTMLynhnGEDYLLHLIDTPGHVD---FRAEVSRSYAS---CGGALLLV 163
                 67888899*********9666677777766554488999999***9999998863322123559*******665...33467777774...99****** PP

                 ETTTTCSHHHHHHHHHH CS
    MMR_HSR1  84 daseeklkpldeeleel 100
                 das++ +++  ++++++
  EEA19182.1 164 DASQG-VQA--QTVANF 177
                 *9944.533..344444 PP

>> EFG_II  Elongation Factor G, domain II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   8.3e-06     0.017       2      71 ..     355     427 ..     354     431 .. 0.86

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 8.3e-06
      EFG_II   2 PePvislaiepkskadedklskaLarlleEDptlrverdeeTketilsG.....mGelHleivverlkreykvev 71 
                 P++++++a  p++ +  + l+++ ++l+  D +++v+  +e+ e + +G     +G+lH  +  +rl++e+++++
  EEA19182.1 355 PKSMVFVAAYPSDADHFEHLEDSVNQLVLNDRSITVQ--KESSEALGAGfrlgfLGTLHCSVFEDRLRHEHGASI 427
                 999******************************9987..5777777555333338***************99876 PP

>> SRPRB  Signal recognition particle receptor beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.0   1.1e-05     0.022      19      99 ..     102     178 ..      66     197 .. 0.67

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 1.1e-05
                 HHHHHHHS.S---B---SS-EEETTG...GGTT-SEEEETT-GCCSHHHHHHHHHHGGEEEEEEEEETTS-HHHHHHHHHHH CS
       SRPRB  19 lftrLttd.svkktvtSqessaalkvksekgskltliDfPGheklrqklleklkaksslkglvfvvDStidpkevkevAEll 99 
                 ++ +L  + +   tv +q  ++ ++  + ++  l+liD PGh+ +r +++ +    +s  g + +vD++    ++++vA ++
  EEA19182.1 102 VLDKLDVErERGITVKAQTCTMLYNH-NGEDYLLHLIDTPGHVDFRAEVSRS---YASCGGALLLVDASQ-GVQAQTVANFY 178
                 44444444244445555555555555.888999***************9988...566777777788764.34556666665 PP

>> RF3_C  Class II release factor RF3, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   1.7e-05     0.033      11      86 ..     359     437 ..     347     472 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1.7e-05
                 EEEEEEESSGGGHHHHHHHHHHHHHCT.SSEEEEET.TS..S-EEEEESSTHHHHHHHHHHHHHH---EEEEE-S--EE CS
       RF3_C  11 lfarvrlkdplkrkqlrkgleqLaeEG.avqvfkeeeag..eelilgaVGqLQfeVveeRlknEYgvevrleslpysla 86 
                 +f     +d+ +  +l+  ++qL      + v ke+++     + lg +G+L   V+e+Rl++E+g+++ +++  + + 
  EEA19182.1 359 VFVAAYPSDADHFEHLEDSVNQLVLNDrSITVQKESSEAlgAGFRLGFLGTLHCSVFEDRLRHEHGASILITPPTVPVK 437
                 57777788999999999999999754424555544433343779************************99987665554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (663 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       568  (0.0316805); expected 358.6 (0.02)
Passed bias filter:                      532  (0.0296726); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.46
# Mc/sec: 4322.66
//
Query:       EEA19183.1  [L=130]
Description: hypothetical protein PMAA_014430 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (130 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       499  (0.027832); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.29s 00:00:00.67 Elapsed: 00:00:00.42
# Mc/sec: 929.72
//
Query:       EEA19184.1  [L=431]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.2e-05   23.5  24.1    8.4e-05   22.8  24.1    1.4  1  Opy2      Opy2 protein
  ------ inclusion threshold ------
       0.29   11.0   2.5       0.64    9.9   2.5    1.5  1  LapA_dom  Lipopolysaccharide assembly protein A domain


Domain annotation for each model (and alignments):
>> Opy2  Opy2 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8  24.1   9.4e-09   8.4e-05       1      35 []      19      51 ..      19      51 .. 0.99

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 9.4e-09
        Opy2  1 CVsCpdsapsCPsCpsgeeCvltaqtCtsCaktyC 35
                CV+C  ++p C +C++ge+Cv +++tCt+C++t+C
  EEA19184.1 19 CVTCT-TEPVC-NCAAGESCVESSRTCTECPTTTC 51
                ****9.*****.*********************** PP

>> LapA_dom  Lipopolysaccharide assembly protein A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   2.5   7.1e-05      0.64      32      56 ..      84     108 ..      70     110 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 7.1e-05
    LapA_dom  32 llgwllslwsylrlrrelrrlkkki 56 
                  +g++l++w+++r+rr+++++++ +
  EEA19184.1  84 AIGVFLFWWFVIRKRRQAQAAQQSV 108
                 68888999*************9975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (431 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1029  (0.0573931); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.26s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 2786.41
//
Query:       EEA19185.1  [L=422]
Description: Rad51 family DNA repair protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00098   18.4   0.0     0.0025   17.1   0.0    1.7  1  Rad51     Rad51


Domain annotation for each model (and alignments):
>> Rad51  Rad51
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   0.0   1.4e-07    0.0025      46      94 ..      95     148 ..      85     260 .. 0.73

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 1.4e-07
                 TTSSHHHHHHHHHHHTTS-TTTS-.....-SSEEEEEESSS---GGGGHHHHHH CS
       Rad51  46 frsGktqlchtlcvtvqlplelgG.....gegkavyidtegtfrperlveiaer 94 
                 ++ Gk+ql + l  +  lp + +G       g++v +dt+g +  +rl +i e 
  EEA19185.1  95 SGGGKSQLVYYLIAMSVLPASFNGhkldgRGGAVVLVDTDGRLDVQRLYDIIES 148
                 678****************98765111116799*****************9853 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (422 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       679  (0.0378716); expected 358.6 (0.02)
Passed bias filter:                      597  (0.033298); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.45
# Mc/sec: 2793.12
//
Query:       EEA19186.1  [L=286]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.7e-17   61.8   0.3    1.1e-16   61.4   0.3    1.1  1  Lactamase_B    Metallo-beta-lactamase superfamily
     0.0085   15.6   0.0      0.021   14.4   0.0    1.6  1  Lactamase_B_2  Beta-lactamase superfamily domain


Domain annotation for each model (and alignments):
>> Lactamase_B  Metallo-beta-lactamase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.4   0.3   1.2e-20   1.1e-16       3     197 .]      29     223 ..      27     223 .. 0.96

  Alignments for each domain:
  == domain 1  score: 61.4 bits;  conditional E-value: 1.2e-20
                  CCSSEEEEEEETTCEEEES--SCHHHHHHHH.HHHHHTSGGGGEEEEE-SBSSHHHHTTGGGCTTHHCCEETCCEHHHHCCHCHHHHHHHHHCCHH.. CS
  Lactamase_B   3 pdpvnsyliegdggviLiDtGtsteaaraal.elaalglkpkdvdavilTHlHlDHiGglgglveatdvpvgavaeeapalfmeeaddaasrkgll.. 97 
                  + p++++li + ++++L+Dt ++  ++ a+   ++a   ++ +++++  TH+H DH++g++ + e+++ ++++  +  +a+++  +  + + ++++  
   EEA19186.1  29 WSPISCTLIHNSKSAVLVDTPITIKQTEALAdWIKATLAPDTKLEYIYTTHAHGDHYFGNPVILEHFPGAKCVATASVAAGIEKTLAASIPIWQGWfp 126
                  5789****************99999998888789****************************************************9999999999** PP

                  ...TTCHCGCCEEEEETTTEECCCTEEEEEHECTTSTSCCEEEEEETTCCEEEECTTTSSHHCCCCCC.TTCEEE-SHCHHHHHHHHHHHHHHHCHSE CS
  Lactamase_B  98 ...lagvsadkpdvdeeeldgnaggrralyvtggpghghghgvveygggkvlftGDallagetgridltlrgaevrdpsdaekyldsllklaglkaev 192
                     +  ++   p+  +e ++++ +g+ +++v + +  +  +  ++ ++ +++++GD+++  +   + +      +  p   +++l++l+++a+lk+++
   EEA19186.1 127 dgqILSERQTVPESLPETGEFFIDGHSLFGVDVSHSDTDASSFLHVPDLDLVVAGDVVYGDCYQFLAE------ANTPEKRKSWLNALDQIAALKPSI 218
                  ***9999****************************************************777777777......9*********************** PP

                  EEESS CS
  Lactamase_B 193 lvpgH 197
                  +vpgH
   EEA19186.1 219 VVPGH 223
                  ***** PP

>> Lactamase_B_2  Beta-lactamase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.0   2.3e-06     0.021       4      73 ..      45     113 ..      43     137 .. 0.75

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 2.3e-06
                    EES--TTHHHH.HTCGGS--S.SS--..SEEEEE-SS--HHHHGGGGCCCC.C--EEEEEEEEHHHHHHCCTT CS
  Lactamase_B_2   4 LiDagpdlrqq.alralqPve.lrdelppidaVllthaHyDHlaglltlre.lrpkklplyapkgvlavlean 73 
                    L+D+   + q  al  + +++ + d+  +++ +  thaH DH+ g + + e +    ++ +a+++v+a +e+ 
     EEA19186.1  45 LVDTPITIKQTeALADWIKATlAPDT--KLEYIYTTHAHGDHYFGNPVILEhF--PGAKCVATASVAAGIEKT 113
                    66666666555433333455556667..9**********************43..347788888888877765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (286 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       423  (0.0235931); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.30s 00:00:00.79 Elapsed: 00:00:00.48
# Mc/sec: 1787.48
//
Query:       EEA19187.1  [L=304]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.9e-26   93.1   0.3    2.3e-26   92.8   0.3    1.1  1  NmrA             NmrA-like family
    8.7e-18   64.9   0.0    1.7e-17   63.9   0.0    1.6  2  NAD_binding_10   NAD(P)H-binding
    1.6e-06   27.8   0.3    4.9e-06   26.2   0.1    2.0  2  Epimerase        NAD dependent epimerase/dehydratase family
    0.00059   20.1   0.1     0.0022   18.3   0.0    1.9  2  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma
     0.0018   17.8   0.1     0.0038   16.7   0.1    1.6  1  adh_short        short chain dehydrogenase
  ------ inclusion threshold ------
       0.01   15.9   0.2      0.022   14.9   0.2    1.6  1  DapB_N           Dihydrodipicolinate reductase, N-terminus
       0.01   16.2   0.1      0.023   15.1   0.1    1.6  1  NAD_binding_7    Putative NAD(P)-binding
      0.016   15.1   0.3      0.027   14.4   0.3    1.4  1  3HCDH_N          3-hydroxyacyl-CoA dehydrogenase, NAD binding
      0.023   15.1   0.2      0.056   13.9   0.2    1.7  1  Semialdhyde_dh   Semialdehyde dehydrogenase, NAD binding doma
      0.024   13.8   0.0       0.04   13.0   0.0    1.3  1  RmlD_sub_bind    RmlD substrate binding domain
      0.024   14.0   0.5      0.066   12.5   0.4    1.9  1  THF_DHG_CYH_C    Tetrahydrofolate dehydrogenase/cyclohydrolas
      0.031   15.0   1.0       0.11   13.2   0.2    2.3  3  DXP_reductoisom  1-deoxy-D-xylulose 5-phosphate reductoisomer
      0.061   12.7   0.0      0.085   12.2   0.0    1.2  1  GDP_Man_Dehyd    GDP-mannose 4,6 dehydratase
       0.17   11.2   0.1        0.4   10.0   0.1    1.6  2  2-Hacid_dh_C     D-isomer specific 2-hydroxyacid dehydrogenas


Domain annotation for each model (and alignments):
>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.8   0.3   1.8e-29   2.3e-26       1     228 [.       9     230 ..       9     267 .. 0.93

  Alignments for each domain:
  == domain 1  score: 92.8 bits;  conditional E-value: 1.8e-29
                 EEESSTTSHHHHHHHHHHHHHT-EEEEEES-S-SHHHHHHHHSTTEEEES-TT-HHHHHHHHTT-SEEEE---GG..S-HHHHHHHHHHHHHHHS-SEE CS
        NmrA   1 IlviGaTGrqGksvvrallkaghkvralvRdtkselakslkeaGvelvkgdlddkeslvealkgvdvvfsvtgfy..skeiedgkklvdAakeaGvkhf 97 
                 ++v+Ga+G+ Gks v+all +g++v  ++R+t++ ++     +Gv  +k + ++++sl+ea+++ d+v+s++g+   ++ + ++k+l+dAa +aGvk f
  EEA19187.1   9 VVVVGASGSVGKSTVKALLGEGFQVTGVTRETSKATLP----EGVRHIKSE-YSEASLREAFDDQDAVISTIGSItpGEALTIQKQLIDAAIAAGVKVF 102
                 78******************************999885....6*****987.789******************999*********************** PP

                 EEEE---GG.GT.SSS---TTTHHHHHHHHHHHHC..TS-EEEEEE-EEGGG-BSSS-SS-BEEE-TTS.-EEEEESS-TTS-EE-HHHHHHHHHHHHH CS
        NmrA  98 iySslgddndrsnaeepavphfdsKaeieeyvral..gipytfvyagffmenflsllaqlkvgdtappedkvtllgpgnpkavlldaeeDiGafvikil 194
                 ++S++g d    +a+e  +p+ + K++  +y++     i  t v++g      l  +     g ++ p+ +vt+   g+ +     +   +G++++k l
  EEA19187.1 103 FPSEYGIDTSDPSAQE-YIPFLADKIQTLDYLKTQqdKISWTAVVSGSMFDWGLDIPGF---GGLNVPASTVTIFDGGDISFEAT-NLFQVGRAIAKCL 196
                 ******9998888888.9**************998889**********99999995554...66777777*********766666.99*********** PP

                 HHHHHHTTEEEEE-SEEE-HHHHHHHHHHHHTS- CS
        NmrA 195 kdprklkgkriklagntlsgneivelfekkigkt 228
                 k+p+  k++++ + + t++ n +++++ek++gk+
  EEA19187.1 197 KKPDLSKNQYVYVNSFTVTQNRVLAALEKAAGKK 230
                 *********************************8 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.9   0.0   1.4e-20   1.7e-17       1     149 [.      13     153 ..      13     199 .. 0.80
   2 ?   -2.9   0.0       4.2   5.4e+03      79      96 ..     217     234 ..     204     248 .. 0.67

  Alignments for each domain:
  == domain 1  score: 63.9 bits;  conditional E-value: 1.4e-20
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHHCTTTCEEEE--TT-CCHHHHHHTT-SEEEES---TCC..HHHHHHHHHHHHHHCT--EE CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpeklaeleaeeglevvegdvtdvedlaealkgadaVvsalggggk..deegaknivdaakeagvkRf 93 
                     GA+G+vG+  vk ll + g++vt ++R+++k++ l+  eg++ ++ + + +++l+ea++++daV+s++g+       ++ k+++daa +agvk f
      EEA19187.1  13 GASGSVGKSTVKALLGE-GFQVTGVTRETSKAT-LP--EGVRHIKSEYS-EASLREAFDDQDAVISTIGSITPgeALTIQKQLIDAAIAAGVKVF 102
                     9****************.5*************9.86..8*******997.89****************77444337777*************888 PP

                     EEEEETTTTSGCGCHHHHHHHHCCHHHHHHHHHHHHHHHH..SSSEEEEEEE-CEE-S CS
  NAD_binding_10  94 vlvsaigvgdevpgefgewnkellkaylaakraaeellra..sgldwTivrpggLtde 149
                        s  g++ + p++      + + + la+k +  ++l++   ++ wT v  g + d 
      EEA19187.1 103 FP-SEYGIDTSDPSA------QEYIPFLADKIQTLDYLKTqqDKISWTAVVSGSMFDW 153
                     66.888999654443......2345789999999999977547999**9988887764 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 4.2
                     HHHHHHHHHCT--EEEEE CS
  NAD_binding_10  79 knivdaakeagvkRfvlv 96 
                     +++++a+++a  k+f + 
      EEA19187.1 217 NRVLAALEKAAGKKFTVS 234
                     456677777777766553 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.2   0.1   3.8e-09   4.9e-06       1      93 [.       9      96 ..       9     144 .. 0.78
   2 ?   -1.9   0.0       1.4   1.8e+03      87     115 ..     208     236 ..     188     240 .. 0.65

  Alignments for each domain:
  == domain 1  score: 26.2 bits;  conditional E-value: 3.8e-09
                EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHCEEEE--TT-HHHHHHHHHHHT-SEEEE--S---HHHHHHSHHHHHHHHTH CS
   Epimerase  1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledlelveldltdrsalerlfkeeqpdavihlAavggvaassedpadfieknlq 93
                ++V+Ga+G +G+ +vkall +g +v+g++r++s+    + e ++ ++ ++ ++ +l+++f+  + davi   +  ++++  + ++++i++ ++
  EEA19187.1  9 VVVVGASGSVGKSTVKALLGEGFQVTGVTRETSKAT--LPEGVRHIKSEYSEA-SLREAFD--DQDAVISTIGSITPGEALTIQKQLIDAAIA 96
                68*****************************66655..555668888888865.599999*..67***9996666666655555555554444 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 1.4
                 HHHHHTHHHHHHHHHHHHHTCTEEEEEEE CS
   Epimerase  87 fieknlqgtlnlleaarkagvkrllflsS 115
                 ++++ ++ + ++l a+ ka  k++    S
  EEA19187.1 208 YVNSFTVTQNRVLAALEKAAGKKFTVSES 236
                 33334455667888888887778776655 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   1.7e-06    0.0022       1      98 [.       9     103 ..       9     138 .. 0.77
   2 ?   -1.1   0.0       1.6   2.1e+03      25      56 ..     203     238 ..     187     245 .. 0.47

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 1.7e-06
                      EEEE--.SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHHHTTSSEEEE-SSGG.......GHHHHH CS
  Sacchrp_dh_NADP   1 vliiGa.GsvGqavaellarhfdvdaeitvadrskeklealaakalgvrfeaialdaenyeavLaallkegdlvvnlsppi.......ssldvl 86 
                      v+++Ga GsvG+++++ l+ ++ +  ++t ++r+ +k  a++    gvr+++ +   +     L ++  ++d+v++ +++i          +++
       EEA19187.1   9 VVVVGAsGSVGKSTVKALLGEG-F--QVTGVTRETSK--ATLP--EGVRHIKSEYSEAS----LREAFDDQDAVISTIGSItpgealtIQKQLI 91 
                      89******************98.6..9**********..4432..57777776665444....66699************99887777777899 PP

                      HHHHHHT-EEEE CS
  Sacchrp_dh_NADP  87 kaCietgvhyvd 98 
                      +a+i++gv +  
       EEA19187.1  92 DAAIAAGVKVFF 103
                      999999998765 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 1.6
                      G..EEEEEES..SHHHHHHHHCHHTTTCEEEEE--T CS
  Sacchrp_dh_NADP  25 a..eitvadr..skeklealaakalgvrfeaialda 56 
                      +   + v ++  +++++ a+++ka+g++f+  + ++
       EEA19187.1 203 KnqYVYVNSFtvTQNRVLAALEKAAGKKFTVSESTV 238
                      224344433300334444444555666666666555 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.1     3e-06    0.0038       2      37 ..       8      43 ..       7      76 .. 0.80

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 3e-06
                EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHH CS
   adh_short  2 vvlvtGassGIGraiakelakeGakvvvvdrseekl 37
                 v+v+Gas+ +G+ ++k+l+ eG++v+ v r+ +k+
  EEA19187.1  8 KVVVVGASGSVGKSTVKALLGEGFQVTGVTRETSKA 43
                69*************************999887665 PP

>> DapB_N  Dihydrodipicolinate reductase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   0.2   1.7e-05     0.022       2      72 ..       8      72 ..       7      98 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.7e-05
                EEEEETTTSHHHHHHHHHHHHSTTEEEEEEEETTCSTTTTTBHHHHSSSS--S-BEB.SSHHHHHHH-SEEE CS
      DapB_N  2 kvavvGasGrmGkevvkaveeaedlelvaavdrkeselegkdagellglgklgvavt.ddleevlekadvli 72
                kv+vvGasG +Gk+ vka+   e+++++++  ++++++         g+++++ + + ++l e+++++d +i
  EEA19187.1  8 KVVVVGASGSVGKSTVKALLG-EGFQVTGVTRETSKAT------LPEGVRHIKSEYSeASLREAFDDQDAVI 72
                8*******************9.9******998887333......3334444444444466777777777666 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.1   0.1   1.8e-05     0.023       8      69 ..       7      75 ..       1      95 [. 0.77

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 1.8e-05
  NAD_binding_7  8 kkvlvvGg.GevAarkvrklleagakvtvvapev.keeleelvklaeeel.....ekdlegadlviaat 69
                   +kv+vvG+ G+v+ + v+ ll +g +vt v+ e+ k+ l+e v+++++e+     ++ +++ d vi ++
     EEA19187.1  7 QKVVVVGAsGSVGKSTVKALLGEGFQVTGVTRETsKATLPEGVRHIKSEYseaslREAFDDQDAVISTI 75
                   789999955*********************999644455577887777764222244466666777766 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.3   2.1e-05     0.027       1      68 [.       8      76 ..       8      97 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 2.1e-05
                EEEEE--.SCCHHHHHHHHHHTT-EEEEE-S..-HHHHHHHHHHHHHHHHCCTTTTSS-HHHHCCCHHCEE CS
     3HCDH_N  1 kvaviGa.GtmGagiaavfasagleVvlvdi..seealekalekieksleklvekgklkeeeveaalaris 68
                kv v+Ga G +G++  ++++ +g++V+ v +  s+++l ++ ++i+++++++  +++++  + +a++++i 
  EEA19187.1  8 KVVVVGAsGSVGKSTVKALLGEGFQVTGVTRetSKATLPEGVRHIKSEYSEASLREAFD--DQDAVISTIG 76
                699***99******************99877557888999********99999999988..4444555544 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.2   4.3e-05     0.056       1      73 [.       8      74 ..       8     106 .. 0.57

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 4.3e-05
                    EEEEETTTSHHHHHHHHHHHC.TSSEEEEEEEESTTTTTSBHHHHSGGGTTTECEBEEEGGGGGCTT-SEEEE- CS
  Semialdhyde_dh  1 kvaivGatGyvGqellrlLee.hpevelvvllsssrsaGkklaeavkaleegkdlkvedvdeeelkevdivfla 73
                    kv +vGa+G vG+  ++ L      ++++ ++ +++ + +  + + ++ +e+++ ++++    ++++ d v++ 
      EEA19187.1  8 KVVVVGASGSVGKSTVKALLGeG--FQVTGVTRETS-KATLPEGVRHIKSEYSEASLRE----AFDDQDAVIST 74
                    799************99998734..55555444444.3333333333556667777766....44555555444 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   3.1e-05      0.04       2      49 ..       8      55 ..       7      65 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 3.1e-05
                   EEEEESTTSHHHHHHHHHCTTTSEEEEEE-TTT--TTSHHHHHHHHHH CS
  RmlD_sub_bind  2 kilvtGanGqlGseLakqlaeeglevlaltreeldltdaeavaellke 49
                   k++v+Ga+G +G+  +k+l  eg++v+++tre+   t +e v+++ +e
     EEA19187.1  8 KVVVVGASGSVGKSTVKALLGEGFQVTGVTRETSKATLPEGVRHIKSE 55
                   799*************************************99998766 PP

>> THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.4   5.1e-05     0.066      37      72 ..       7      42 ..       2      96 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 5.1e-05
                   -EEEEE---TTTHHHHHHHHHCTT-EEEEE-TTSCC CS
  THF_DHG_CYH_C 37 kkvvvvGrsnivgkplallLleknatVtvchsktkd 72
                   +kvvvvG+s  vgk+    Ll ++  Vt + ++t++
     EEA19187.1  7 QKVVVVGASGSVGKSTVKALLGEGFQVTGVTRETSK 42
                   79**************************99999965 PP

>> DXP_reductoisom  1-deoxy-D-xylulose 5-phosphate reductoisomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.2   8.8e-05      0.11       1      50 [.       9      56 ..       9      96 .. 0.84
   2 ?   -3.0   0.0       8.6   1.1e+04      13      34 ..     128     149 ..     127     152 .. 0.80
   3 ?   -0.5   0.0       1.5   1.9e+03      33      86 ..     189     242 ..     167     272 .. 0.56

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 8.8e-05
                     EEEESTTSHHHHHHHHHHHHCTTTEEEEEEEESSTHHHHHHHHHHHT-SE CS
  DXP_reductoisom  1 vviLGsTGSIGtqtLdvieenpdkfevvalaagsnvellaeqakefkpkl 50
                     vv++G++GS+G++t++ +    + f+v++++ +++ ++l e ++++k ++
       EEA19187.1  9 VVVVGASGSVGKSTVKALL--GEGFQVTGVTRETSKATLPEGVRHIKSEY 56
                     789***********88765..566*******9999999999888888776 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 8.6
                      HHHHHHHHCTTTEEEEEEEESS CS
  DXP_reductoisom  13 qtLdvieenpdkfevvalaags 34 
                      qtLd ++ ++dk++ +a++ gs
       EEA19187.1 128 QTLDYLKTQQDKISWTAVVSGS 149
                      8999999999999888887665 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 1.5
                      SSTHHHHHHHHHHHT-SEEEESSHHH.HHHHHHHHHHTTSSSEEEESHHHHHHHH CS
  DXP_reductoisom  33 gsnvellaeqakefkpklvavadeea.aeelkealkekelktevlvGeealkela 86 
                      g+ +++ ++     k ++v v++ +   +++ +al ek +  +++v e+++++l 
       EEA19187.1 189 GRAIAKCLKKPDLSKNQYVYVNSFTVtQNRVLAAL-EKAAGKKFTVSESTVEQLW 242
                      56666666666666666666655443123333333.2344444444444444444 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   6.6e-05     0.085       2      46 ..      11      56 ..      10      83 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 6.6e-05
                   EETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TT.HHHHHCTTT. CS
  GDP_Man_Dehyd  2 iTGiaGfiGsylaelLlekgyevhgivrrsssfnt.griehlakdp 46
                   + G +G +G  +++ Ll +g++v+g++r +s+ ++ + ++h++++ 
     EEA19187.1 11 VVGASGSVGKSTVKALLGEGFQVTGVTRETSKATLpEGVRHIKSEY 56
                   88**************************998876536677776533 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.1   0.00031       0.4      37      98 ..       7      74 ..       2      97 .. 0.76
   2 ?   -3.6   0.0       4.8   6.1e+03      47      58 ..     188     199 ..     187     217 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00031
                  SEEEEES-.SHHHHHHHHHHHHTT-EEEEESSSHHHHH.....CHHHHTCEECSHHHHHHH-SEEEE- CS
  2-Hacid_dh_C 37 ktvGiiGl.GrIGqavakrlkafgmkviaydrskkkee.....eeeelgvelvsleellaesDivslh 98
                  ++v ++G+ G++G+++ k l + g++v+++ r  +k +     +  + +++ +sl e++ + D v+ +
    EEA19187.1  7 QKVVVVGAsGSVGKSTVKALLGEGFQVTGVTRETSKATlpegvRHIKSEYSEASLREAFDDQDAVIST 74
                  456666644************************99877777443334445566999999999988765 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 4.8
                   HHHHHHHHHHHT CS
  2-Hacid_dh_C  47 IGqavakrlkaf 58 
                   +G+a+ak+lk+ 
    EEA19187.1 188 VGRAIAKCLKKP 199
                   799999998865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (304 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       631  (0.0351944); expected 358.6 (0.02)
Passed bias filter:                      572  (0.0319036); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 2022.03
//
Query:       EEA19188.1  [L=258]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.1e-20   73.7   1.6    3.7e-20   73.5   1.6    1.0  1  Abhydrolase_6  Alpha/beta hydrolase family
     0.0079   15.5   0.1      0.022   14.0   0.1    1.7  1  Hydrolase_4    Serine aminopeptidase, S33
  ------ inclusion threshold ------
      0.036   13.7   0.1      0.071   12.7   0.1    1.5  1  Abhydrolase_1  alpha/beta hydrolase fold
      0.075   12.7   0.2       0.12   12.1   0.2    1.3  1  PGAP1          PGAP1-like protein


Domain annotation for each model (and alignments):
>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.5   1.6   8.2e-24   3.7e-20       1     219 [.       9     244 ..       9     245 .. 0.71

  Alignments for each domain:
  == domain 1  score: 73.5 bits;  conditional E-value: 8.2e-24
                    EEEE--GC.....G.CHHHHHHHHCCTCEEEEE--TTSTS-GGCS--HHHCHHHHHHHCCTT..TTSEEEEEETCHHHHHHHHHHCC......... CS
  Abhydrolase_6   1 vlllHGagssassW.lvapLaallaagvhvlapDlpGhGrsdpppldledladlaalldelaagggpvvlvGHSlGGalalaaapla......... 86 
                    +ll+HGa++++++W ++ p++++l+  v   ++Dlp + +  p  +  +d+a+++  +++l + g+ v++++HS+GG++a+a   +          
     EEA19188.1   9 ILLVHGAWHGSWCWkFQIPMLEALGYSV--ETVDLPCT-SKVPGTTQSDDAAQVRSSVESLLSKGKSVIVLAHSYGGSIASA---GMrglsgehng 98 
                    89************65668888888888..9*******.24555566666677777777777799*****************...66656887788 PP

                    ..EE.EEES-..----TTTS----TTHHHHHHTT-CCCCHCCH........S-HSCCCCHHH.C.CCCHCHCCCGHHHHCCHHCHTTCCHHTT-TT CS
  Abhydrolase_6  87 lvvg.vlldppptalpagllaaalelllallallrllawlsre........plprlfladed.a.daawrarlarlaallaglgllpaaawadlpv 171
                     + g ++l++  ++ p g+  +  e+++ +++l     w+s          p++ lf+ ++  a +  w+ +  r+   +a+++  p++ w d   
     EEA19188.1  99 MLLGlIALCA--VMHPGGY--DQGEFIRNAGSLPFVVSWDSPVeglcvvkdPAS-LFYTPDVpAdRIKWALPQVRPHSMAASMDIVPPQVWQDDHY 189
                    4455699999..4444444..333333333332222355533333445442444.77775554357888888888888888888889999999999 PP

                    GC...EEECTT-CHHH....HCHHCCCH.STTEEETCE...SSS-HHHHSHHHHHH CS
  Abhydrolase_6 172 pl...lvlggeDplvp....rllerlla.qagarlpvvlpgaGHlphleepdevae 219
                    +    ++ +++D ++p    + + +++  q+++++  +l+g+GH+p+l+ pd+va 
     EEA19188.1 190 TGqlgYIRCTADVSIPierqDSIIEAAGgQERWVI-RTLEGSGHSPFLSCPDQVAT 244
                    998878889****777333333335555799****.************999***95 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.0   0.1   4.9e-06     0.022       3     102 ..       5     101 ..       3     119 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 4.9e-06
  Hydrolase_4   3 pkavvvlvHGlaehsgryaelaeaLaaqGfavyalDhrGhGrsegkrghvpsfddyvdDlaafvekvkeehpelplfllGhSmGGliallyl....lr 96 
                   k +++lvHG    s+  +  +  L a G++v ++D     + +g +   ++  ++   +++++      ++++ +++l+hS GG ia + +     +
   EEA19188.1   5 TKPTILLVHGAWHGSWCWKFQIPMLEALGYSVETVDLPCTSKVPGTTQ-SDDAAQVRSSVESLL------SKGKSVIVLAHSYGGSIASAGMrglsGE 95 
                  577899999999999999999999999999999999988877755554.555555555555554......66779*************9988544334 PP

  Hydrolase_4  97 ypdkva 102
                  +   + 
   EEA19188.1  96 HNGMLL 101
                  444444 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.1   1.6e-05     0.071       1      89 [.       7      87 ..       7      88 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 1.6e-05
                   SEEEEE-STTTCGGGGTTGHHHHHHHHTTSEEEEEEETTSTTSSSTTTGB.CHHSHHHHHHHHH.HHHHHCT.TSSEEEEEETHHHHHHHH CS
  Abhydrolase_1  1 pvlvilhGlpgssdvwaerglapaLakdgfdvillDlrGvgySspapacinddygtasvaddld.rildalg.ddkltlvGhSmGGmiala 89
                   p+++++hG   +s+ w   + +p L+  g+ v ++Dl+  + S+ + ++++      + a+ ++  +   l   +++++++hS+GG ia+a
     EEA19188.1  7 PTILLVHGAWHGSWCWK--FQIPMLEALGYSVETVDLP--CTSKVPGTTQS------DDAAQVRsSVESLLSkGKSVIVLAHSYGGSIASA 87
                   68999999999887544..599999999********97..88888888644......456666655555555055566**********985 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.2   2.7e-05      0.12      88     107 ..      68      87 ..      46     105 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 2.7e-05
       PGAP1  88 keptsviliGHSmGGivara 107
                  + +svi+++HS+GG +a a
  EEA19188.1  68 SKGKSVIVLAHSYGGSIASA 87 
                 5779*************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (258 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       419  (0.02337); expected 358.6 (0.02)
Passed bias filter:                      400  (0.0223102); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 1829.97
//
Query:       EEA19189.1  [L=147]
Description: hypothetical protein PMAA_014490 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-28   99.6   0.0    1.3e-28   99.3   0.0    1.0  1  DUF3224   Protein of unknown function (DUF3224)


Domain annotation for each model (and alignments):
>> DUF3224  Protein of unknown function (DUF3224)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.3   0.0   7.1e-33   1.3e-28       3     126 .]       9     144 ..       7     144 .. 0.96

  Alignments for each domain:
  == domain 1  score: 99.3 bits;  conditional E-value: 7.1e-33
                 EEEEEEEEEEEECCE-TT.T-EEEEEEEEEEE-TTEEE.EEEEEEEEEE.....CCTTEEEEEEEEEEEEE.ETTEEEEEEEEEEEEEETTEEE..EEE CS
     DUF3224   3 gtFtvkswdekaveeaed.gaklgrasvekafsGdleG.tskgemllaya....eeegsaayvglervegt.ldgrkGsfvlqhsgtfaagkas..lef 92 
                 ++ ++ swde++++++++  ++l+ asv++a++G +++ ts+++ml++ a    e++gsa++v+++ +e++ ++grkGsf++q +g+f+a+k++  ++f
  EEA19189.1   9 SPARILSWDEDRSPATQStFPRLTPASVKMALDGLNASvTSSYQMLYLPAgpgcEKDGSAVFVFTDLIESEdFEGRKGSFMTQGTGKFDATKHRveGTF 107
                 678899**********8889**************************************************99*********************999*** PP

                 EE-TT--EETTTTE...EEEEEEEEETTTEEEEEEEE CS
     DUF3224  93 evVpgsGtgeLagl...sGtgeieiaekgkheyefey 126
                 e+Vp+sG+g+L +l    G+g++ ++ek+++++++++
  EEA19189.1 108 EIVPRSGKGDLGELfkeGGNGSFLSDEKNPSQVNYRF 144
                 ****************99***********99998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (147 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       186  (0.0103743); expected 358.6 (0.02)
Passed bias filter:                      178  (0.00992805); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.29s 00:00:00.70 Elapsed: 00:00:00.45
# Mc/sec: 976.79
//
Query:       EEA19190.1  [L=109]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.4e-24   84.3   0.0    5.6e-24   84.0   0.0    1.1  1  Mitochondr_Som1  Mitochondrial export protein Som1


Domain annotation for each model (and alignments):
>> Mitochondr_Som1  Mitochondrial export protein Som1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.0   0.0   3.1e-28   5.6e-24       1      88 [.       1      86 [.       1      87 [. 0.90

  Alignments for each domain:
  == domain 1  score: 84.0 bits;  conditional E-value: 3.1e-28
  Mitochondr_Som1  1 MaPpvpvysaseleervqvkekl..ekkrkeeeveLkkCeLkelvQyeCtfkeskkeekekkiiClpvkRlfrrCkekekglnvEvTaee 88
                     MaP vp++ a++l++rvq+ +++  ek+rk e  +L+kCeL+elvQy+C+  e+    ++  + C+p++RlfrrC   ++gl+vE+T++e
       EEA19190.1  1 MAPLVPIFAAEDLPSRVQIVHRGfkEKRRKGEPIDLHKCELMELVQYSCNPPEEG-ILAPGVVKCKPIVRLFRRC---ADGLTVETTSWE 86
                     9********************9999999999*******************44443.333444*************...99*********8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (109 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       336  (0.0187406); expected 358.6 (0.02)
Passed bias filter:                      244  (0.0136092); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.37u 0.29s 00:00:00.65 Elapsed: 00:00:00.44
# Mc/sec: 749.75
//
Query:       EEA19191.1  [L=348]
Description: bromodomain associated domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.6e-21   75.5   0.5    9.4e-21   74.1   0.5    1.8  1  TAF8_C    Transcription factor TFIID complex subunit 8 C-term
    2.1e-11   43.7   0.0    3.7e-11   42.9   0.0    1.4  1  Bromo_TP  Bromodomain associated


Domain annotation for each model (and alignments):
>> TAF8_C  Transcription factor TFIID complex subunit 8 C-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.1   0.5     1e-24   9.4e-21       1      49 []     185     233 ..     185     233 .. 0.99

  Alignments for each domain:
  == domain 1  score: 74.1 bits;  conditional E-value: 1e-24
      TAF8_C   1 yiPshlPpfPppHTYkrTpvyneretdpkkirekaaeqsrlaekaLrkL 49 
                 yiP+h+P+fP++HTY++Tpv++eretdp++ire  +e sr++e+aLrkL
  EEA19191.1 185 YIPAHFPHFPSKHTYRFTPVFTERETDPRRIRELGMEDSRNGEEALRKL 233
                 9***********************************************8 PP

>> Bromo_TP  Bromodomain associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.9   0.0   4.1e-15   3.7e-11       4      69 ..      58     123 ..      55     128 .. 0.95

  Alignments for each domain:
  == domain 1  score: 42.9 bits;  conditional E-value: 4.1e-15
                 HHHHHHHHHHHHHHHHT-SEE-HHHHHHHHHHHHHHHHHHHHHHHHHHTTSS-SS--HHHHHHHHH CS
    Bromo_TP   4 arsllkvvvsqileeaGfdsaeesaLEtLteiaqkYirelgeqaksfaehagRseptlkDvvltLq 69 
                  + ll+ ++  il++ G+d ae++aL+++++ +++Yi+ l+  a + + +a+R++p ++D++++Lq
  EEA19191.1  58 VTHLLECSIGLILTKTGYDMAEPAALDAFRQATEEYILHLSSFARQSMTAARRIQPIPQDFEFALQ 123
                 578899999*******************************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (348 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       398  (0.0221987); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.24s 00:00:00.70 Elapsed: 00:00:00.41
# Mc/sec: 2558.37
//
Query:       EEA19192.1  [L=62]
Description: cytochrome c oxidase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0075   16.4   0.0     0.0085   16.2   0.0    1.0  1  COX6C     Cytochrome c oxidase subunit VIc
  ------ inclusion threshold ------
       0.12   12.7   0.0       0.13   12.6   0.0    1.1  1  DUF4233   Protein of unknown function (DUF4233)


Domain annotation for each model (and alignments):
>> COX6C  Cytochrome c oxidase subunit VIc
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   9.4e-07    0.0085       7      56 ..       8      57 ..       4      61 .. 0.91

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 9.4e-07
       COX6C  7 mrgllakrlkrhlvvafvlslgvaaaykfavaepRKkayadFYknYDaek 56
                + g+l++ l   l  af l ++ ++++ ++   pR +a +++Y   +ae 
  EEA19192.1  8 ITGILRRGLVLDLSTAFGLGTTFGYLWWYGYHLPRVRARDNYYARLEAER 57
                568999999999********************************999886 PP

>> DUF4233  Protein of unknown function (DUF4233)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   1.5e-05      0.13      71      96 ..      15      42 ..       2      48 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.5e-05
     DUF4233 71 gfvvp..amfvvgvvFaavWvyalvlgr 96
                g+v+   + f +g  F  +W+y ++l r
  EEA19192.1 15 GLVLDlsTAFGLGTTFGYLWWYGYHLPR 42
                67777779999************99855 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (62 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       300  (0.0167327); expected 358.6 (0.02)
Passed bias filter:                      244  (0.0136092); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.30s 00:00:00.74 Elapsed: 00:00:00.49
# Mc/sec: 383.73
//
Query:       EEA19193.1  [L=183]
Description: NEDD8 conjugating enzyme (UbcL), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.3e-38  131.0   0.0      3e-38  130.6   0.0    1.1  1  UQ_con     Ubiquitin-conjugating enzyme
  ------ inclusion threshold ------
      0.041   13.6   0.0      0.048   13.4   0.0    1.2  1  Prok-E2_B  Prokaryotic E2 family B


Domain annotation for each model (and alignments):
>> UQ_con  Ubiquitin-conjugating enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  130.6   0.0   3.4e-42     3e-38       1     139 [.      33     167 ..      33     168 .. 0.89

  Alignments for each domain:
  == domain 1  score: 130.6 bits;  conditional E-value: 3.4e-42
                 HHHHHHHHHHHSTTTTEEEEEEETTEECEEEEEEEB.TTSTTTTEEEEEEEE--TTTTTS--EEEESST-SCTTBETTSBB-CGGGSTTT--TTSHHHH CS
      UQ_con   1 rlqkelkelakkkpsgisaklvddenlfewkvlikgpedtpYeggvFklelefpedYPlkpPkvkfvtkifHPnvdksGevcldiLkeekWspaltles 99 
                 r+q++l+el+   +++  + +   +++ +++++i++ ++++Y+gg F++++++++++P++pPkvk+++ki+HPn+d +G+vcl+iL+e+ W+p+l+l+ 
  EEA19193.1  33 RVQRDLQELS-LGSTMKMTFPNP-DDILNFTLTIEP-DEGMYKGGSFNFTFSINQNFPHDPPKVKCTQKIYHPNIDLEGNVCLNILRED-WKPVLNLNA 127
                 5677777653.333333344444.59********99.**************************************************55.********* PP

                 HHHHHHHHHHS--TTS-SSHHHHHHHHHTHHHHHHHHHHH CS
      UQ_con 100 vllsiqsLlaepnpesplnkeaakllkkdreeykkkvkey 139
                 v++ +q L+ epn ++plnkeaa++l+ +re +kk+vk++
  EEA19193.1 128 VIVGMQFLFLEPNASDPLNKEAAEDLRLNREGFKKNVKNS 167
                 *************************************875 PP

>> Prok-E2_B  Prokaryotic E2 family B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   5.4e-06     0.048      33     113 ..      66     145 ..       8     154 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 5.4e-06
   Prok-E2_B  33 t.....sggtvdlrlvypdsfpllppavflqdpeqlkllpHintfggaLClleeeldldewdpngsvadvl.eqlqqvLnegisgde 113
                       +gg++++++ ++ +fp  pp+v  ++       p i   +g +Cl       + w+p  ++ +v+       L+ ++s+  
  EEA19193.1  66 PdegmyKGGSFNFTFSINQNFPHDPPKVKCTQKI---YHPNIDL-EGNVCL---NILREDWKPVLNLNAVIvGMQFLFLEPNASDPL 145
                 0445558**********************99988...3445555.6*****...677777888888888874333345556666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (183 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       507  (0.0282782); expected 358.6 (0.02)
Passed bias filter:                      402  (0.0224218); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 1236.46
//
Query:       EEA19194.1  [L=901]
Description: chitin synthase ChsG [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.9e-71  237.1   0.0    3.4e-70  235.2   0.0    1.8  2  Chitin_synth_1   Chitin synthase
    2.3e-28   97.9   0.0    4.5e-28   97.0   0.0    1.5  1  Chitin_synth_1N  Chitin synthase N-terminal
    2.3e-25   89.2   0.1    1.7e-20   73.2   0.0    2.2  2  Chitin_synth_2   Chitin synthase
    2.6e-09   37.3   0.1    2.6e-09   37.3   0.1    2.6  3  Glyco_trans_2_3  Glycosyl transferase family group 2
    0.00018   21.5   0.0    0.00045   20.2   0.0    1.7  1  Glyco_tranf_2_3  Glycosyltransferase like family 2


Domain annotation for each model (and alignments):
>> Chitin_synth_1  Chitin synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  235.2   0.0   9.4e-74   3.4e-70       1     163 []     211     379 ..     211     379 .. 0.93
   2 ?   -1.2   0.0      0.49   1.7e+03      40      57 ..     841     858 ..     828     874 .. 0.75

  Alignments for each domain:
  == domain 1  score: 235.2 bits;  conditional E-value: 9.4e-74
  Chitin_synth_1   1 mynEdkellarTLkgvmkNieelkkrkkskvwgkds..WkkivVcivsDGrekideetldvlaalgvyqegvakkkvngkevkahlfeyttqlsv 93 
                     +ynEdk+l +rTL+gvm+Ni+++++ kks++w+k +  W+kivVc+v+DG++++d++tldvla++g+yq+gv+k++v+gke++ah+feyttqlsv
      EEA19194.1 211 YYNEDKQLTSRTLHGVMQNIRDIVNLKKSEFWNKGGpaWQKIVVCLVFDGIDPCDKDTLDVLATIGIYQDGVMKRDVDGKETVAHIFEYTTQLSV 305
                     7********************************88777********************************************************* PP

  Chitin_synth_1  94 deelklkene....kslvpvqllfclkeknakkinShrWlfnafarllqPevcvlldvGtkpgkkslyklwkaf 163
                     +++++l + +    ++l pvq++fclk+kn+kkinShrWlfnaf+r+l+Pe+cvlld+Gtkpg+ks+++lw+af
      EEA19194.1 306 TPSQQLIRPTddgpSTLPPVQMIFCLKQKNSKKINSHRWLFNAFGRILNPEICVLLDAGTKPGPKSILSLWEAF 379
                     774443332223458999******************************************************98 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.49
  Chitin_synth_1  40 ivVcivsDGrekideetl 57 
                       Vci sDG+++   + +
      EEA19194.1 841 LAVCITSDGVDEFGFTNK 858
                     579******988655554 PP

>> Chitin_synth_1N  Chitin synthase N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.0   0.0   1.3e-31   4.5e-28       1      73 []     131     210 ..     131     210 .. 0.90

  Alignments for each domain:
  == domain 1  score: 97.0 bits;  conditional E-value: 1.3e-31
  Chitin_synth_1N   1 tkkvkLlngnlvl.dlpvpkkllkalp...eeeke....seEfthmRYtAvTcdPddft.kegytLRqalygReteLlIviT 73 
                      t+kvkL++g+++  d+pvp+++ +a++   ++  +    seEfthmRYtA+TcdP++ft ++gy+LR+a+y+R+teLlI+iT
       EEA19194.1 131 TRKVKLVQGSVLSvDYPVPSAIQNAVQakyRN--DleggSEEFTHMRYTAATCDPNEFTlHNGYNLRPAMYNRHTELLIAIT 210
                      69*******98766*************76533..23456******************************************9 PP

>> Chitin_synth_2  Chitin synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.2   0.0   4.7e-24   1.7e-20     203     384 ..     356     547 ..     346     598 .. 0.77
   2 !   13.6   0.2   5.3e-06     0.019     433     494 ..     700     761 ..     688     785 .. 0.83

  Alignments for each domain:
  == domain 1  score: 73.2 bits;  conditional E-value: 4.7e-24
  Chitin_synth_2 203 eivlmvdadtkvapdsltrlvaalvkdpeilglcGetkiankkesw......vtaiqvfeyyishhlskafesvfGsvtclPGcfslyrikaakg 291
                     ei++++da tk  p s+  l  a+ +d+ + g cGe +     + w      + a q fey is  l k +es fG v+ lPG fs+yr +a  g
      EEA19194.1 356 EICVLLDAGTKPGPKSILSLWEAFYNDKDLGGACGEIHAML-GKGWrnlvnpLVAAQNFEYKISNILDKPLESSFGYVSVLPGAFSAYRFRAIMG 449
                     8999********************************87543.23331111224577************************************999 PP

  Chitin_synth_2 292 adgkwvPil.vspeiveeysenvvdtl..hkknllllGedrylt.tlllktfpkrktvfvpqakcktvaPdtfkvllsqrrrwinst....vhnl 378
                         +   +  ++ + ++  ++ ++ +   kkn+ +l edr l   l+ k  +k +  +v+ +k++t +P+    ++sqrrrw+n +    v+ l
      EEA19194.1 450 --RPLEQYFhGDHTLSKQLGKKGIEGMniFKKNM-FLAEDRILCfELVAKAGSKWHLSYVKASKAETDVPEGAAEFISQRRRWLNGSfaagVYSL 541
                     ..33444440456666778888888652168886.689****98469999***********************************6422225555 PP

  Chitin_synth_2 379 lelvlv 384
                     + + ++
      EEA19194.1 542 MHFSRI 547
                     555555 PP

  == domain 2  score: 13.6 bits;  conditional E-value: 5.3e-06
  Chitin_synth_2 433 iplvllaivlGlpailivltarkleyvawllvyllalPifnfvlPlyafwhlddfswGetrv 494
                     i ++ la+ +Gl  +   l    +++ + +  yll +  f  +l +yaf +  d swG    
      EEA19194.1 700 IIIIALAATFGLYFVASFLYMDPWHMFTSFPAYLLIMSSFINILNVYAFSNWHDVSWGTKGA 761
                     668889****************************************************7655 PP

>> Glyco_trans_2_3  Glycosyl transferase family group 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       1.2   4.3e+03      21      48 ..     127     156 ..     124     164 .. 0.71
   2 !   37.3   0.1   7.2e-13   2.6e-09       2     192 ..     358     584 ..     357     593 .. 0.75
   3 ?   -5.8   5.1         5   1.8e+04     153     165 ..     703     715 ..     622     748 .. 0.59

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 1.2
  Glyco_trans_2_3  21 aelaspevaivqgpvlvm..nvanwleela 48 
                      + +a+++v++vqg vl +  +v + +++  
       EEA19194.1 127 RRYATRKVKLVQGSVLSVdyPVPSAIQNAV 156
                      5677889******99974467777776665 PP

  == domain 2  score: 37.3 bits;  conditional E-value: 7.2e-13
  Glyco_trans_2_3   2 illlDaDtvlppdclreiaaela.spevaivqgpvlvm......nvanwleelaalffaedhgkdilvrealgrvvpsvGsgaflrrsalq... 85 
                       +llDa t + p +++ + + +  + + + ++g + +m      n  n l+  + ++++++ + d +  +++g v  ++G+ ++ r +a+    
       EEA19194.1 358 CVLLDAGTKPGPKSILSLWEAFYnDKDLGGACGEIHAMlgkgwrNLVNPLVAAQNFEYKISNILDKPLESSFGYVSVLPGAFSAYRFRAIMgrp 451
                      5899******9999999977665489999*******9999854444566677777779********************************9999 PP

  Glyco_trans_2_3  86 .............evg........gwdgdessvsEDfdmglrl.qrkG..yrvrfvpeslvkekspltlraalrQrkRwayGcel...eklill 152
                                   ++g         ++ ++ +++ED  +++ l +++G  +++ +v +s   + +p     ++ Qr+Rw+ G       + ++ 
       EEA19194.1 452 leqyfhgdhtlskQLGkkgiegmnIFK-KNMFLAEDRILCFELvAKAGskWHLSYVKASKAETDVPEGAAEFISQRRRWLNGS-FaagVYSLMH 543
                      988888888777644477666666555.467************446667788899999999*********************6.2334444445 PP

  Glyco_trans_2_3 153 vrllgylgsllwsalplhl.allllfsllalalvlllllll 192
                      ++++   g+ ++  ++lh+ +l+ +f+ + ++++l  ++l+
       EEA19194.1 544 FSRIYKSGHNILRMFVLHFqMLYNTFNTILTWFALASYWLT 584
                      55554456666666666663444445555554444444444 PP

  == domain 3  score: -5.8 bits;  conditional E-value: 5
  Glyco_trans_2_3 153 vrllgylgsllws 165
                      + l + +g+++++
       EEA19194.1 703 IALAATFGLYFVA 715
                      2222222222222 PP

>> Glyco_tranf_2_3  Glycosyltransferase like family 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.0   1.2e-07   0.00045      67     229 ..     334     531 ..     299     532 .. 0.84

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 1.2e-07
  Glyco_tranf_2_3  67 arnlgstgksralneal.ravksdlvllvDdDtvvePdtlkrllqff.ltpkvgavgtpvfllnrstl......vsalgalefaerhlrflaar 152
                      ++   +++ ++ l++a+ r+ ++++ +l+D+ t  +P ++ +l  +f ++++ g + +  +++ ++ +      + a++++e+++ ++    + 
       EEA19194.1 334 KNSKKINSHRW-LFNAFgRILNPEICVLLDAGTKPGPKSILSLWEAFyNDKDLGGACGEIHAMLGKGWrnlvnpLVAAQNFEYKISNILDKPLE 426
                      44446667777.444541456799**************************************9999776666667777**********999999 PP

  Glyco_tranf_2_3 153 ralg.vltlnGsgslir.revlkele.......................gldplflltdDyelglrlrr...agfrtayvpgaavrevfpsslk 218
                       ++g v  l G++s++r r+++ ++                         + ++  l++D +l+++l +    +++  yv+ +  ++  p+  +
       EEA19194.1 427 SSFGyVSVLPGAFSAYRfRAIMGRPLeqyfhgdhtlskqlgkkgiegmnIFKKNMFLAEDRILCFELVAkagSKWHLSYVKASKAETDVPEGAA 520
                      9999778888*******55678888899*****************9886566688889*********999777788889999999999****** PP

  Glyco_tranf_2_3 219 ayikqrnRwvy 229
                      ++i qr+Rw+ 
       EEA19194.1 521 EFISQRRRWLN 531
                      *********86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (901 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       553  (0.0308439); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.70u 0.26s 00:00:00.96 Elapsed: 00:00:00.42
# Mc/sec: 6384.99
//
Query:       EEA19195.1  [L=377]
Description: Pyridoxal-phosphate dependent enzyme, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.9e-69  234.4   0.1    2.3e-69  234.0   0.1    1.1  1  PALP             Pyridoxal-phosphate dependent enzyme
     0.0021   18.0   0.1        2.5    8.1   0.0    2.4  2  ADH_zinc_N       Zinc-binding dehydrogenase
  ------ inclusion threshold ------
        0.1   11.9   0.1       0.16   11.3   0.1    1.2  1  DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family


Domain annotation for each model (and alignments):
>> PALP  Pyridoxal-phosphate dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  234.0   0.1   3.9e-73   2.3e-69      21     278 ..      65     346 ..      53     362 .. 0.88

  Alignments for each domain:
  == domain 1  score: 234.0 bits;  conditional E-value: 3.9e-73
                 CCEEEEEEGGGSTTSBTTHHHHHHHHHH..HHTT.....TTTSEEEEEBSSHHHHHHHHHHHHHT-EEEEEEETTS-HHHHHHHHHTT-EEEEECCHHH CS
        PALP  21 gvplflKlEslnptgSfKdRgaeyllar..lkeg.....tgaktvveassGNhgralAaaaallGlkvtivvpadaspekvallrllGaevvevggdyd 112
                 ++++++K+E+l+ +g+fK+Rga ++l r     +      ++++vv+ ssGNh++alA+a++ l+++ +iv+p+ +sp+k+a +++lGa+vv++g++  
  EEA19195.1  65 KIRFWFKCENLQRIGAFKARGAFHALIRviQ--EqgeeeVRRRGVVTHSSGNHAQALALAGKTLNIPTHIVMPSISSPSKIASTQSLGANVVFSGSTEP 161
                 5679************************753..3347778******************************************************99999 PP

                 HHHHHHHHHHHHSTTCEE--TTTSHHHHHHHHTHHHHHH.....HHTT.TTEEEEEEE-SSSHHHHHHHHHHHH....HSTT-EEEEEEEC..TTCGGT CS
        PALP 113 eavaaaaelaaegegaylvsqfdnptviegygtiglEil.....eqlg.gkpdavvvpvGgGgliaGiaaglke....rrpdvrvigvepe..gsdala 199
                 e+ a+++e+ ++ +ga++v+++d+p+vi+g+gt+glE+      +q+g + +dav+ pvGgGgl aG+a+ + +    ++ ++ v+g+ep+  g+d + 
  EEA19195.1 162 ERTAVMKEIQSQ-TGAIFVPPYDHPDVILGQGTLGLEMEaqyeeAQHGkKTLDAVFTPVGGGGLNAGVATWFSKsakeGGKKTLVFGAEPSfeGADDCR 259
                 99999*******.*************************745555555599************************77755555***************** PP

                 TCCS..S.SS..B.SSS.CCSTCSCGTTCCHHHHSEEEE..EEEEEEHHHHHHHHHHHHHHHSB-B-HHHHHHHHHH.......HHHH CS
        PALP 200 rslragrrvtvpvsdtiadglavgspselafelldrlvd..eivtvsdeealeamrllarregivvepssaaalaal.......klre 278
                 r+l+ag+rv+  +s+tiadgl+++ ++  +++++ +  +   +++v+d+++ +am+l+ +r+++vveps+ ++la++       k +e
  EEA19195.1 260 RGLAAGERVPAVSSKTIADGLRTP-VGLTNWAVISDPSKvaGVYSVTDDQIKRAMKLVLERMKVVVEPSAVVGLAVClfdedfrKRVE 346
                 ************************.99999999955444449***********************************88765443333 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.1   0.0   0.00042       2.5      16      67 ..     131     220 ..     113     248 .. 0.74
   2 !    7.7   0.0   0.00056       3.4      35      75 ..     320     370 ..     292     375 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00042
                 EEEE.EESSHHHHHHHHHTTESEEEET....TTCHHHHHHHHHT.................................TTSSEEEEEESSC CS
  ADH_zinc_N  16 evia.vdsseeklelakklGadeviny....keadlverikelt.................................ggegvdvvfecvG 67 
                 ++++   ss++k++  ++lGa++v+      +++ + ++i++ t                                 g++ +d+vf  vG
  EEA19195.1 131 HIVMpSISSPSKIASTQSLGANVVFSGstepERTAVMKEIQSQTgaifvppydhpdvilgqgtlglemeaqyeeaqhGKKTLDAVFTPVG 220
                 45555889******************9665533357777777777777777777777777777777777777777766777777777777 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.00056
                 ESEEEET...........TTCHHHHHHHHHTTTSSEEEEEESSCSHHHHHHH CS
  ADH_zinc_N  35 adeviny...........keadlverikeltggegvdvvfecvGsgatleaa 75 
                 +++v+ +           +e d+ +r+++  g++g d+ + ++G ++t+ea 
  EEA19195.1 320 MKVVVEPsavvglavclfDE-DFRKRVEKEGGEDGWDIGIVFSGGNTTVEAI 370
                 44455555555555555456.9**********************77777654 PP

>> DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   2.6e-05      0.16      38     116 ..     104     178 ..      95     180 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 2.6e-05
                      -SEEEEESSHHHHHHHHHHHTTTTTT-EEEEESSS-THHHHHHHHTT-EEEEE-B-TTTSSB-GGGCGGG--TTEEEEE CS
  DegT_DnrJ_EryC1  38 vkhaiavssGtaAlhlaLralgvgpgdeVIvpsltFvatanavlelgakpvfvDvdpdtynidpaaieaaitertkaIl 116
                       + +++ ssG +A +laL    ++  + +++ps++  + +++ + lga++vf   +     ++  a+ + i+++t aI+
       EEA19195.1 104 RRGVVTHSSGNHAQALALAGKTLNIPTHIVMPSISSPSKIASTQSLGANVVFSGST----EPERTAVMKEIQSQTGAIF 178
                      56789**************9888888**************************8766....4556666666777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (377 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       402  (0.0224218); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.24s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2765.07
//
Query:       EEA19196.1  [L=398]
Description: Ketol-acid reductoisomerase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.9e-46  155.3   0.0    1.5e-45  154.8   0.0    1.2  1  IlvN           Acetohydroxy acid isomeroreductase, NADPH-bind
    2.7e-40  138.0   0.0      4e-40  137.4   0.0    1.3  1  IlvC           Acetohydroxy acid isomeroreductase, catalytic 
  ------ inclusion threshold ------
       0.15   12.2   0.0       0.36   11.0   0.0    1.6  1  NAD_binding_2  NAD binding domain of 6-phosphogluconate dehyd
       0.16   12.6   0.0       0.34   11.5   0.0    1.6  1  F420_oxidored  NADP oxidoreductase coenzyme F420-dependent


Domain annotation for each model (and alignments):
>> IlvN  Acetohydroxy acid isomeroreductase, NADPH-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  154.8   0.0   3.3e-49   1.5e-45       2     161 ..      77     242 ..      76     244 .. 0.93

  Alignments for each domain:
  == domain 1  score: 154.8 bits;  conditional E-value: 3.3e-49
                 HHTS-EEEES-SHHHHHHHHHHHHTT--EEEEE-TT-HHHHHHHHTT-....EEEEHHHHHHT-SEEEE-S-HHHHHHHHHHHTGGG--TT-EEEESSS CS
        IlvN   2 lkgkkiaviGyGsqGhaqalnlrdsgldvvvglregsksvkkAkeegf....evltvaeavkkadvvmiliPDelqkevyeeeiepnlkegkalafahG 96 
                 +k+ ++a+iGyGsqGh q+lnlrd+gl+v++g+r++++s+k+A ++g+    +  +v+ a++k  +vm+l+ D +q+e +  +i+p l++gk+l f+hG
  EEA19196.1  77 FKNDTLALIGYGSQGHGQGLNLRDNGLNVIIGVRKDGTSWKEAIQDGWvpgkNLFDVETAINKGTIVMNLLSDAAQSETW-PQIKPLLTKGKTLYFSHG 174
                 57899*****************************************97333356789***********************.99**************** PP

                 HHHHTT...SS---TTSEEEEEEESS-SHHHHHHHHTT----EEEEEEE-SSS-HHHHHHHHHHHTTH CS
        IlvN  97 fnihfg...likppkdvdvvlvAPkgpGhlvreeyeegkGvpaliaveqdasgkakelalayakgiGa 161
                 f+ +f+   ++++p+d+dv+lvAPkg G++vr+ ++eg+G+ + iav qd++gkake+a+a+  ++G+
  EEA19196.1 175 FSPVFKdltKVDIPADIDVILVAPKGSGRTVRSLFREGRGINSSIAVFQDVTGKAKEKAIAMGVAVGS 242
                 **99973335789*****************************************************97 PP

>> IlvC  Acetohydroxy acid isomeroreductase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.4   0.0     9e-44     4e-40       1     143 [.     250     394 ..     250     395 .. 0.93

  Alignments for each domain:
  == domain 1  score: 137.4 bits;  conditional E-value: 9e-44
                 HHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHHTT--HHHHHHHHTHHH.HHHHHHHHHHHHHHHHHHS-HHHHHHHHHHHHHHS-HHHHHHHHHHHHH CS
        IlvC   1 FkeEtetDlfgEqavLcGgvselveagFetlveaGyspelAyfeclhel.klivdliyegGiakmresiSdtaeygdltagprviteevkeemkeilee 98 
                 F++E+++Dl+gE+++L+Gg+++++ a++e+l+e+G+sp++A++e+++e+ +++++li  +G+++m+ ++S+ta++g+ ++ p++ +++ k+++ e++++
  EEA19196.1 250 FEKEVYSDLYGERGCLMGGIHGMFLAQYEVLRERGHSPSEAFNETVEEAtQSLYPLIGANGMDWMYAACSTTARRGAIDWSPKF-KDALKPVFDELYTS 347
                 99**********************************************99**********************************.************** PP

                 HHTTHHHHHHHHHHHT..TSHHHHHHHHHHHTSHHHHHHHHHHHCHT CS
        IlvC  99 iqsGefakevieenka..grpelkklrkeeaeheiekvgkklralmp 143
                 +++G+++++ +e n++   r++++k  +e ++ ei+++gk +r+l+p
  EEA19196.1 348 VKTGKETQRSLEYNSQpdYRERYEKELEEIRNLEIWRAGKAVRSLRP 394
                 ************9544435555666666666*************997 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0     8e-05      0.36       2      86 ..      82     169 ..      81     174 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 8e-05
                    EEEE--SHHHHHHHHHHHHTT-EEEEE-SSH.HHHHHHHHTTEEE-SSHHHHHHHC..SEEEE-SSSHHHHHHHHHSHCCC--TT-EE CS
  NAD_binding_2   2 igfiGlGvMGsnmalnllkagykvavynrtk.ekveelvaegakaaesieelvasl..dvvitmvkagkavdeviegllealkkgdil 86 
                    +++iG G  G+   lnl ++g +v++  r+   + +e++++g ++ +++ ++ +++   ++++ + +++a  e++ ++++ l kg++l
     EEA19196.1  82 LALIGYGSQGHGQGLNLRDNGLNVIIGVRKDgTSWKEAIQDGWVPGKNLFDVETAInkGTIVMNLLSDAAQSETWPQIKPLLTKGKTL 169
                    79**********************998877537899******6666666655555554566666666677788999999999999875 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   7.5e-05      0.34       2      67 ..      82     145 ..      81     169 .. 0.65

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 7.5e-05
                    EEEETTSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC....-EEECECHHHHHHH-SEEEE CS
  F420_oxidored   2 igiiGaGnmgealasgllaagaqpheivvansrnpekaeelaeelg....vkvtavdneeaaeeadvvvl 67 
                    +++iG+G++g++  ++l  +g    +++++  r+    ++++e+++    ++    d e+a+++ ++v  
     EEA19196.1  82 LALIGYGSQGHGQGLNLRDNG---LNVIIG-VRKDG--TSWKEAIQdgwvPGKNLFDVETAINKGTIVMN 145
                    79*******************...****99.55544..33444444334544444456777777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (398 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       506  (0.0282224); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.48
# Mc/sec: 2467.73
//
Query:       EEA19197.1  [L=898]
Description: isochorismatase family protein family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.3e-27   94.7   0.0    1.5e-26   93.8   0.0    1.4  1  2OG-FeII_Oxy_2   2OG-Fe(II) oxygenase superfamily
    2.2e-20   73.5   0.0      7e-20   71.9   0.0    1.8  1  Isochorismatase  Isochorismatase family
    2.9e-05   24.2   0.0      8e-05   22.8   0.0    1.6  1  GST_C            Glutathione S-transferase, C-terminal domain
    7.2e-05   22.9   0.0    0.00016   21.8   0.0    1.5  1  GST_C_3          Glutathione S-transferase, C-terminal domain
     0.0009   19.2   0.0      0.002   18.1   0.0    1.6  1  GST_C_2          Glutathione S-transferase, C-terminal domain


Domain annotation for each model (and alignments):
>> 2OG-FeII_Oxy_2  2OG-Fe(II) oxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.8   0.0   4.3e-30   1.5e-26      16     196 .]     457     641 ..     454     641 .. 0.92

  Alignments for each domain:
  == domain 1  score: 93.8 bits;  conditional E-value: 4.3e-30
  2OG-FeII_Oxy_2  16 ellrelleegpfrqptilggkrvsvqqtllgplgwatdgpgyrysekesvdakplspfpeallrlverlvkaagpegwspnaalvnfYrdga.ri 109
                     ++++++++e+ ++++ +l+g+ +++  + +g ++     p yr+   es   + ++++++a++ ++er+v      g+ +n+al+++Yrdg+ +i
      EEA19197.1 457 DAFEQIQKEVNWQKMYHLSGQVPRLVAV-QGVVSPDKSFPIYRHPADESPVLEAFTKTVDAVRVCAERIV------GHPLNHALIQMYRDGQdNI 544
                     5789999******************987.999*****99******9999999*****************9......79***************** PP

  2OG-FeII_Oxy_2 110 glHqDke.esaleapivSlSLGasatfrfgkesree.......eiiailLesGdllvmggesrkay.Hgvprikkdtapele.leelrtrRinlT 194
                     ++H+Dk+ +   ++ iv++SLGa++++++++++ +        + +++++++G++ ++g +s++ + Hg++++k+ +++++  +++++++Ri+lT
      EEA19197.1 545 SEHSDKTlDIVRGSSIVNVSLGAQRVMTLRTKKSAPtegedgrQKQQVPMPHGSMFILGPQSNTRWlHGIRPDKRPQSEKSCeEKAYNGERISLT 639
                     *******999********************7765556777888********************************65544446999********* PP

  2OG-FeII_Oxy_2 195 fR 196
                     fR
      EEA19197.1 640 FR 641
                     *9 PP

>> Isochorismatase  Isochorismatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.9   0.0   1.9e-23     7e-20       2     167 ..      21     229 ..      20     237 .. 0.94

  Alignments for each domain:
  == domain 1  score: 71.9 bits;  conditional E-value: 1.9e-23
  Isochorismatase   2 alvviDmqndfv.eegvkeseeisavveninkllkaarkagipviftrdvhe........................................le 54 
                      al+++D+qndfv ++g+  + +  ++++ i  l++++r+ g  v+++r ++e                                         +
       EEA19197.1  21 ALLLLDFQNDFVrPNGRLPVRKTLDFIDLIPGLVQSFRRTG-EVVWVRTQYEgprpviddygseiiitsagsldtknqkkgrhgrqescsdvND 113
                      9*************************************999.7************************************************999 PP

  Isochorismatase  55 evkgdlderkaaphfkpgttgaelvpelaple...gdvvvdKtrfsafagtdldeiLkelgiktivlaGiatdvCVeatardaldlGyevvvvs 145
                       v ++++    +p++ p+t g ++   +        d+v++K+ +sa  +++++  L+++ +++++++G   +v V ata+da++ G+ +++++
       EEA19197.1 114 VVDPEAFLSGPEPACLPQTAGVQFPAPILAAIdheHDIVIEKSDYSALQSPGMVLSLRSRFVTELYICGSLSNVSVYATALDAAQQGFSITLIE 207
                      99999999*************99854443333366*********************************************************** PP

  Isochorismatase 146 DAvaalspelhdaalkrlkqaf 167
                      D+++ +s   h+ a++rl++ +
       EEA19197.1 208 DCMGYRSFARHEEAVRRLADIV 229
                      ******************9765 PP

>> GST_C  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8   0.0   2.2e-08     8e-05      28      92 ..     815     882 ..     801     882 .. 0.90

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 2.2e-08
                 HHHHHHHHHHHHHHHH..TSSSSSTTSSCHHHHHHHHHHHHHHHHTTTTT.TTTSHHHHHHHHHHHTS CS
       GST_C  28 lekvaevlsaleeelk..kqdylvGdkltlADialvpilnwlqrlglafg.qekfpnlkawlerimar 92 
                 ++  + +ls  +e+l+  +q+y++G+ lt+ D+al pil + ++ ++ ++ + ++p l+ +++ri  r
  EEA19197.1 815 SRTEFGQLSSWNERLReaGQHYIAGQALTIDDLALWPILHQIETQKGIISgSSQYPYLSTYYQRIEKR 882
                 566667788888999999**********************************************9876 PP

>> GST_C_3  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   0.0   4.6e-08   0.00016      34      89 ..     823     882 ..     817     887 .. 0.86

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 4.6e-08
                 HHHHHHHHCHGTSSSSTTS--HHHHHHHHHHHHHHHH....TCC.CC-HHHHHHHHHHHTS CS
     GST_C_3  34 kyfekvlkkkgggylvgdklTyADlalfqvldgleea....eal.kkfpklkalyervear 89 
                 + +++ l + g+ y++g+ lT+ Dlal+ +l+++e +    +   +++p l  +y+r+e+r
  EEA19197.1 823 SSWNERLREAGQHYIAGQALTIDDLALWPILHQIETQkgiiS-GsSQYPYLSTYYQRIEKR 882
                 5566777768888************************97543.159************987 PP

>> GST_C_2  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   5.5e-07     0.002      15      69 .]     822     878 ..     816     878 .. 0.87

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 5.5e-07
                 HHHCTTT---SS...CTTCS--HHHHHHHHHHHHHHHHHHS----..TT-HHHHHHHHH CS
     GST_C_2  15 ldaleahLadsp..flfGdqptlaDialapflvrlraagpgfdir..eaypnlraWler 69 
                 l+ ++++L+     +++G  +t+ D al+p l++ ++    + i   ++yp l ++++r
  EEA19197.1 822 LSSWNERLREAGqhYIAGQALTIDDLALWPILHQIETQKG-I-ISgsSQYPYLSTYYQR 878
                 77899999988889*********************99983.2.33459*********98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (898 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       383  (0.021362); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.66u 0.28s 00:00:00.94 Elapsed: 00:00:00.45
# Mc/sec: 6027.39
//
Query:       EEA19198.1  [L=282]
Description: enoyl-CoA hydratase/isomerase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.9e-36  125.7   0.0    9.7e-36  123.3   0.0    1.8  1  ECH_1           Enoyl-CoA hydratase/isomerase
    1.1e-29  104.0   0.0    6.5e-28   98.2   0.0    2.0  2  ECH_2           Enoyl-CoA hydratase/isomerase
  ------ inclusion threshold ------
       0.13   11.9   0.0       0.82    9.4   0.0    2.1  2  DNA_pol3_theta  DNA polymerase III, theta subunit


Domain annotation for each model (and alignments):
>> ECH_1  Enoyl-CoA hydratase/isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.3   0.0   1.6e-39   9.7e-36       6     249 ..      20     280 ..      17     281 .. 0.87

  Alignments for each domain:
  == domain 1  score: 123.3 bits;  conditional E-value: 1.6e-39
                 EEEEEE--CGCTTEE-HHHHHHHHHHHHHHHHSTTECEEEEEE.BTSEEEEEB-HHHHHHHHCHHHHHHHC..............CHHHHHHHHHHSSS CS
       ECH_1   6 vaviklnrPeavNalsaelltEliqalekleddksvravvLtG.gdkaFaaGadlkemaeeekakqallke..............evlelwtklytvpk 89 
                 va +  nrP+++N+  +e+  El   +++l d++ vravv  G gd+aF aG+d+k++a++    q+  ++              e+++  + +  ++k
  EEA19198.1  20 VAHVETNRPDKLNSYFEEMWLELRTIFNTLSDSPDVRAVVFSGaGDRAFTAGLDVKAAAQGLLGPQDGKSKdparvatqlrrhidEFQDCISSIERCEK 118
                 89999*****************************************************9986533332221111111112222226788889999**** PP

                 EEEEEE-SEEETHHHHHHHHSSEEEEETTTEEE-GGGGGTS--CTTCHHHHHHHHHHH.HHHHHHHHT-EEEHHHHHHCTSSSEEESG.GGHHHHHHHH CS
       ECH_1  90 pviaavnGaaigGGlelalacDiviaadnasfglnelklGlipgaggtqilarkvGks.kAeeilllgkkisaqealkvGlvdkvvpe.eqlleealel 186
                 pvi a+ G + g  + + +a+Di+ +a+n +f+ +e+ +Gl ++ g   +l++ vG+   ++e++l+++ ++a+ealkvG v+ v    ++ + +a+el
  EEA19198.1 119 PVIVAMHGISYGLAIDISVAADIRLCAKNTAFSVKEVDIGLAADIGTLTRLPKVVGNYgWVKEVALTARVFGAEEALKVGFVSGVYETkQDTVAKAIEL 217
                 ********************************************************8637*************************98868899****** PP

                 HHHHHHSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTSHHHHHHHHHHHTCSH---- CS
       ECH_1 187 aeklaekspaalrqlkealnakledalaeqleaeaklfestfskddikeGlqaflEkrkpefe 249
                 a  +a+ksp a++  ke ln   ++  + +l       ++ ++ +d+   + + lEkr p+fe
  EEA19198.1 218 AGLMASKSPVAVQGTKELLNYSRDHSVKDGLRYTGVWNSAAVQAKDVSAAVLSGLEKRIPTFE 280
                 ************************777777777777777777777999999999****99998 PP

>> ECH_2  Enoyl-CoA hydratase/isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.2   0.0   1.1e-31   6.5e-28       3     175 ..      22     207 ..      20     216 .. 0.88
   2 !    4.8   0.0    0.0027        16     247     304 ..     212     268 ..     203     278 .. 0.81

  Alignments for each domain:
  == domain 1  score: 98.2 bits;  conditional E-value: 1.1e-31
                 EEEE--GGGTT-B-HHHHHHHHHHHHHHCC-TT-SEEEEEESSSSECE--B--HHHHHHHHCS.......-TH....H.HHHHHHHHHHHHHHHC-SS- CS
       ECH_2   3 vitLnrpkalNaLslemvralkealkewekddevklvvlkgagekafCAGgDvralyeaakeg.......kke....e.eeffreeYklnyliatypkp 89 
                 +++ nrp++lN+   em  +l+ ++++ +++++v++vv +gag++af AG Dv+a ++              +    + ++ + e  ++ + i++++kp
  EEA19198.1  22 HVETNRPDKLNSYFEEMWLELRTIFNTLSDSPDVRAVVFSGAGDRAFTAGLDVKAAAQGLLGPqdgkskdP-ArvatQlRRHIDEFQDCISSIERCEKP 119
                 6788*****************************************************98776655555440.144333577777888899********* PP

                 EEEEE-BEEETHHHHHHTTSSEEEE-TT-EEE--GGGGT----TTHHHHHHCSSTTHHHH..HHHH---B-HHHHHHTTS--EE--GG CS
       ECH_2  90 vvalmdGivmGgGvGlsvhgsfrvvtertvfAmPEtaIGlfPDvGgsyfLsrlpgelGly..lalTGarlkgadalaaglathyvpse 175
                 v+  m+Gi  G  + +sv + +r   ++t f++ E+ IGl  D+G+   L+++ g++G    +alT++ +++++al++g+ + + +++
  EEA19198.1 120 VIVAMHGISYGLAIDISVAADIRLCAKNTAFSVKEVDIGLAADIGTLTRLPKVVGNYGWVkeVALTARVFGAEEALKVGFVSGVYETK 207
                 **********************************************99999999999865559****************998777655 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.0027
                 HHHHHHHHHHHHS-HHHHHHHHHHHHHHTTT--HHHHHHHHHHHHHHHHHHSSHHHHH CS
       ECH_2 247 ewakktletlkkrsPtslkvtleqlrrgrklsslaevlrmElrlalrllaekDfveGv 304
                 + a + +  ++++sP++++ t e+l+ +r+ s +++ lr      +++++ kD+   v
  EEA19198.1 212 AKAIELAGLMASKSPVAVQGTKELLNYSRDHS-VKDGLRYTGVWNSAAVQAKDVSAAV 268
                 455667889**********************5.***9999888888888888877666 PP

>> DNA_pol3_theta  DNA polymerase III, theta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.0   0.00014      0.82      38      68 ..      22      52 ..      18      54 .. 0.86
   2 ?   -0.4   0.0      0.16   9.5e+02      27      36 ..     113     122 ..     102     125 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00014
  DNA_pol3_theta 38 qvereqPeaLreYFreRlayyReeskklsrl 68
                    +ve ++P++L +YF+e     R+  ++ls +
      EEA19198.1 22 HVETNRPDKLNSYFEEMWLELRTIFNTLSDS 52
                    79**************999999888888766 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.16
  DNA_pol3_theta  27 kERynmPVva 36 
                      ER ++PV+ 
      EEA19198.1 113 IERCEKPVIV 122
                     59******97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (282 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       360  (0.0200792); expected 358.6 (0.02)
Passed bias filter:                      338  (0.0188521); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.40
# Mc/sec: 2092.72
//
Query:       EEA19199.1  [L=72]
Description: RNA polymerase II general transcription and DNA repair factor TFIIH component Tfb5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-24   85.8   0.7    1.6e-24   85.7   0.7    1.0  1  Tfb5      Transcription factor TFIIH complex subunit Tfb5


Domain annotation for each model (and alignments):
>> Tfb5  Transcription factor TFIIH complex subunit Tfb5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.7   0.7   8.7e-29   1.6e-24       1      68 []       1      67 [.       1      67 [. 0.96

  Alignments for each domain:
  == domain 1  score: 85.7 bits;  conditional E-value: 8.7e-29
        Tfb5  1 MvkaikGvLveCDpaikqlilkldeqepsqkfiiedL.Dethlfvkeevveelkkeleellekntyepe 68
                M++a+kGvLveCDp++k++ilk de++  +++i+edL D++hl++ke++++ lk++l ++l+++ ++pe
  EEA19199.1  1 MPRAVKGVLVECDPSVKAIILKYDEEK--HDYIVEDLdDDRHLVIKESQLQNLKERLGQELDQKVMQPE 67
                9*************************5..9*******8899**********************999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (72 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       965  (0.0538234); expected 358.6 (0.02)
Passed bias filter:                      434  (0.0242066); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.34u 0.26s 00:00:00.60 Elapsed: 00:00:00.38
# Mc/sec: 567.98
//
Query:       EEA19200.1  [L=187]
Description: heat shock protein Hsp30/Hsp42, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.2e-19   70.3   0.2    3.7e-14   52.7   0.1    2.3  2  HSP20       Hsp20/alpha crystallin family
      4e-08   32.7   0.0     0.0038   16.8   0.0    2.5  2  ArsA_HSP20  HSP20-like domain found in ArsA


Domain annotation for each model (and alignments):
>> HSP20  Hsp20/alpha crystallin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   1.4e-06     0.012       1      39 [.      45      84 ..      45      98 .. 0.87
   2 !   52.7   0.1   4.2e-18   3.7e-14      39     101 ..     123     186 ..     109     187 .] 0.83

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 1.4e-06
                E--SSEEEEEEEEE-TT--CCCEEEEEETTE.EEEEEE-- CS
       HSP20  1 dikeeeeefevkldvpglkkeelkvkvednr.vlvkgehe 39
                d++e+++++++  ++pg+++++++++  d + +++kg   
  EEA19200.1 45 DVRESKDAYHLDGELPGIAQKDVEIEFSDPQtLTIKGRSV 84
                6899************************976699999865 PP

  == domain 2  score: 52.7 bits;  conditional E-value: 4.2e-18
                 -......---TT----SS---EEEEEE--STTB-TTT-EEEEETTEEEEEEEBSS--..-------- CS
       HSP20  39 e....eeeedekglikerssrkFsrkftLPenvdadkvkaslkdGvLtvtvpkkepekkkkerkiqi 101
                 +     + ++ k++++ers+++F r+f+ P  vd++ vkaslk+GvLtvtvpk  p+   ++rki i
  EEA19200.1 123 KevskAQGNGYKYWVSERSVGEFHRSFNFPSRVDHNGVKASLKNGVLTVTVPKAAPP---TSRKITI 186
                 245445667889*******************************************99...6788877 PP

>> ArsA_HSP20  HSP20-like domain found in ArsA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.0   4.5e-06      0.04       2      56 ..      51     106 ..      50     107 .. 0.89
   2 !   16.8   0.0   4.2e-07    0.0038      30      62 ..     141     172 ..     141     173 .. 0.95

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 4.5e-06
  ArsA_HSP20   2 deyvlkldLPfvdkeeidlsrs.gdeLtIkignfrRqitLPsvlarkevtsAkfed 56 
                 d y l+ +LP++ +++++++ s  ++LtIk  + r   tLP+  + + ++ A++ed
  EEA19200.1  51 DAYHLDGELPGIAQKDVEIEFSdPQTLTIKGRSVREYHTLPENENPHAPKPASVED 106
                 7899999************999679****************998888888888776 PP

  == domain 2  score: 16.8 bits;  conditional E-value: 4.2e-07
  ArsA_HSP20  30 kignfrRqitLPsvlarkevtsAkfedgvLeIr 62 
                 ++g f+R++  Ps+++   v +A++++gvL+++
  EEA19200.1 141 SVGEFHRSFNFPSRVDHNGV-KASLKNGVLTVT 172
                 589***************99.**********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (187 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       486  (0.0271069); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1364.06
//
Query:       EEA19201.1  [L=568]
Description: MFS multidrug transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-42  145.8  43.1    1.5e-42  145.8  43.1    1.9  2  MFS_1     Major Facilitator Superfamily
    6.4e-11   41.8  11.3    6.4e-11   41.8  11.3    2.7  2  Sugar_tr  Sugar (and other) transporter
    3.2e-09   36.6   3.6    3.2e-09   36.6   3.6    2.7  3  MFS_4     Uncharacterised MFS-type transporter YbfB
    3.2e-05   23.1  21.0    0.00017   20.7   3.8    2.8  2  PUCC      PUCC protein
    0.00064   18.1  10.7     0.0026   16.1   1.7    2.5  2  OATP      Organic Anion Transporter Polypeptide (OATP) family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.8  43.1   4.2e-46   1.5e-42       1     352 [.      59     458 ..      59     459 .. 0.85
   2 ?   -3.6   0.4       1.1   4.1e+03     120     134 ..     532     546 ..     524     552 .. 0.42

  Alignments for each domain:
  == domain 1  score: 145.8 bits;  conditional E-value: 4.2e-46
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlga 99 
                 +++++f+ a+++++++++ +  +a dl  + s   +l++ y++  a +++++Grls+ f+ r++l l+ +l ++gll+ + a+ +++++v+rv++Glg+
  EEA19201.1  59 VACLLFIQATNITTISTTQS-DIAADLD-AFSNTPWLTSSYMISVASLTPVGGRLSQIFSLRSILSLSSFLISVGLLITATAQRFPVFIVGRVITGLGS 155
                 57999**************9.9******.**********************************************55555337788************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 ++++++  +++ ++++k++rg+ ig++++++ +G++ g++++g++a  +gWr+++yi  ++++++  +  l+l  +p+   ++s+ e            
  EEA19201.1 156 ALIYSTQTIIALELSSKKRRGLLIGCVYTTVTVGIAAGAIIAGAMAPRFGWRSLYYIQSPMCFVLTPI--LYLAIPPTGQDKESGPESFkkrlaridyw 252
                 *****************************************************************885..55544444444444444447789****** PP

       MFS_1 189 ..........................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglll 245
                                                              +  p+vp +++++++ vl+   i++ +++++ +++l++lp+y   v+g+s   +
  EEA19201.1 253 giltmtaanvlllyslsrpnisytyiaislvlfaifvavestPAIAAEPIVP-ISIVRSRGVLL-SGISSTGIMMARWAILFYLPVYGIAVRGWS-PAE 348
                 ************************************8887777777777777.********997.77777777889999****************.799 PP

       MFS_1 246 aglllallalvgailallagrls.drlgr.rrrlllallllllaalglallavtssavllll.vlvliGf.glgfvfpsllalasdlappeeagtasgl 340
                 +g+++  + +++a ++ll+g+++ ++ ++  +  l++ +l++l++l++a+l++++s+v+l++ vl++ Gf +++f + ++  ++     p+ +  ++gl
  EEA19201.1 349 GGVIMIPTNAGFALGGLLVGWIHiRKAKSyYISSLVISILFMLSCLSIAVLSTPNSSVILYAiVLFTNGFtCGAFLNYTVSHVLHLTS-PSTHYIVTGL 446
                 998888888888889********88855435566666666677777777777775555555546666888666666666655555555.599999**** PP

       MFS_1 341 fntagslggalg 352
                 ++t++s +g++g
  EEA19201.1 447 ISTFRSTAGSFG 458
                 *********998 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 1.1
       MFS_1 120 graigllsagfslGa 134
                 g a+ ll++++++G+
  EEA19201.1 532 GAALVLLMTFTQAGT 546
                 223333333333333 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.8  11.3   1.8e-14   6.4e-11      46     181 ..      88     217 ..      51     231 .. 0.84
   2 ?   -1.0  10.5      0.17     6e+02      49     158 ..     350     463 ..     337     475 .. 0.74

  Alignments for each domain:
  == domain 1  score: 41.8 bits;  conditional E-value: 1.8e-14
                 .HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHH CS
    Sugar_tr  46 vlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyq 144
                 + + +++s++++  +    ++g l+++f+ +++l  +++l ++g +++a+a+    + v+ivgRv++G+g  l++ + ++ + E++ kk Rg l+++  
  EEA19201.1  88 SNTPWLTSSYMISVASLTPVGGRLSQIFSLRSILSLSSFLISVGLLITATAQ---RFPVFIVGRVITGLGSALIYSTQTIIALELSSKKRRGLLIGCVY 183
                 566788999999888888899*******************************...9******************************************* PP

                 HHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHH CS
    Sugar_tr 145 laitfGilvaaifglglnktsnadgwrillglqlvpa 181
                 + +t+Gi  +ai+  +++   +   wr l ++q+ + 
  EEA19201.1 184 TTVTVGIAAGAIIAGAMAPRFG---WRSLYYIQSPMC 217
                 ************9998877666...777777766554 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.17
                 HHHHHTHHHHHHHHHHHHHHHHHHT..THHHHHHHHHHHHHH.HHHHHH-TTTTSS-TGGGGGHHHHHHHHHHH.HHHHHHHHHTTS-SCCHHHHHHHH CS
    Sugar_tr  49 glivsiflvGaiiGslfagllgdrf..GRkkslliaavlfvi.gavlqaaakgknsvevlivgRvlvGigvGla.svlvPmyisEiApkklRgalvsly 143
                 g+i+  +++G ++G+l++g++  r   ++  s l++++lf+  +  + ++++ ++sv ++++  +  G+ +G++ +++v++ +   +p ++    + + 
  EEA19201.1 350 GVIMIPTNAGFALGGLLVGWIHIRKakSYYISSLVISILFMLsCLSIAVLSTPNSSVILYAIVLFTNGFTCGAFlNYTVSHVLHLTSPSTHYIVTGLIS 448
                 56666678999*********98765114444555555555550555777777779*****************863678888888888888887777777 PP

                 HHHHHHHHHHHHHHH CS
    Sugar_tr 144 qlaitfGilvaaifg 158
                  +  t+G + +ai g
  EEA19201.1 449 TFRSTAGSFGSAIGG 463
                 777777777766655 PP

>> MFS_4  Uncharacterised MFS-type transporter YbfB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.6   3.6   8.8e-13   3.2e-09      63     197 ..     123     256 ..     101     298 .. 0.82
   2 ?    3.1   5.9     0.014        49       7     122 ..     325     447 ..     319     466 .. 0.72
   3 ?   -2.4   0.1      0.63   2.2e+03     199     213 ..     527     541 ..     512     544 .. 0.67

  Alignments for each domain:
  == domain 1  score: 36.6 bits;  conditional E-value: 8.8e-13
       MFS_4  63 agllatvllllamaltesfaaflliRflaGvasAvvlvfgsslvlahaaaarrervgallfaGvGlGiavsgllvllllqlglsasslWlalavlsavl 161
                  + ++  + ll  a ++ f +f++ R+++G++sA++    + ++l+ ++++rr+ ++++++  v +Gia++++++ ++ +   ++ sl+++ + + +vl
  EEA19201.1 123 LSSFLISVGLLITATAQRFPVFIVGRVITGLGSALIYSTQTIIALELSSKKRRGLLIGCVYTTVTVGIAAGAIIAGAM-APRFGWRSLYYIQSPMCFVL 220
                 44445555566778899****************************************************999877655.555667779*********** PP

       MFS_4 162 lllvalllp.raalreasaaaeaakaeqkslpllall 197
                 + ++ l +p  ++ +e+  ++++ k ++++  + +l+
  EEA19201.1 221 TPILYLAIPpTGQDKESGPESFK-KRLARIDYWGILT 256
                 **999999977777777766666.5555555555554 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.014
       MFS_4   7 iGRFsytpiLPal.laegqlslsqagllaaaNylGYLvGallaafalsagaeRlr.......llagllatvllllamal.tesfaaflliRflaGvasA 96 
                 ++R++    LP+  +a  ++s+++ g +     +G+ +G ll   ++ + ++          + +  +++ l+++  +   +s+++++++ f  G + +
  EEA19201.1 325 MARWAILFYLPVYgIAVRGWSPAEGGVIMIPTNAGFALGGLLV--GWIHIRKAKSyyisslvISILFMLSCLSIAVLSTpNSSVILYAIVLFTNGFTCG 421
                 5666666667765467778888888888766667776666655..4444443333334443365555556666655555156788999*********** PP

       MFS_4  97 vvlvfgsslvlahaaaarrervgall 122
                 + l  + s vl+ ++++ + +v +l+
  EEA19201.1 422 AFLNYTVSHVLHLTSPSTHYIVTGLI 447
                 ******************99999876 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 0.63
       MFS_4 199 aYglaGfGYiitatF 213
                 + +laG+++++ +tF
  EEA19201.1 527 TMFLAGAALVLLMTF 541
                 557778888888887 PP

>> PUCC  PUCC protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   8.7   0.00036       1.3      71     162 ..     121     215 ..      50     268 .. 0.61
   2 !   20.7   3.8   4.9e-08   0.00017     253     359 ..     357     465 ..     334     483 .. 0.86

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00036
        PUCC  71 ivlsgkgeae...aaatwaglilaavafllvGlgvslsqTallALladlaeeeerpkvvgllyvmlligivvsaivvgallkdytearLirvvqg 162
                 + ls  + +     +at +   + +v  ++ Glg  l+  +   ++ +l+++++r  ++g +y  +++gi+++ai+ ga+   +    L  + ++
  EEA19201.1 121 LSLSSFLISVgllITATAQRFPVFIVGRVITGLGSALIYSTQTIIALELSSKKRRGLLIGCVYTTVTVGIAAGAIIAGAMAPRFGWRSLYYIQSP 215
                 33333333331111222222222233335667777766666666777888888888888888888888888888888888777766666655554 PP

  == domain 2  score: 20.7 bits;  conditional E-value: 4.9e-08
        PUCC 253 alGtlvGlllaglvlsrglkkarlaslgv..llgllsflllilaallenvallvagvlllGlasGlfavaaltlmldlaaeeraglalGaWGaaQaiaa 349
                 + G  +G ll+g++ +r++k   + sl++  l +l ++++ +l+++ ++v l + +++  G++ G f + +++ +l+l+ + +  +  G+     ++a 
  EEA19201.1 357 NAGFALGGLLVGWIHIRKAKSYYISSLVIsiLFMLSCLSIAVLSTPNSSVILYAIVLFTNGFTCGAFLNYTVSHVLHLTSPSTHYIVTGLISTFRSTAG 455
                 556666777899999999999988888761156788999999999999999************************************************ PP

        PUCC 350 glavllggal 359
                 +++ ++gg++
  EEA19201.1 456 SFGSAIGGGI 465
                 ******9986 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   1.7   7.3e-07    0.0026     132     192 ..     141     201 ..      52     205 .. 0.78
   2 !    6.6   2.0   0.00055         2     337     396 ..     349     409 ..     344     468 .. 0.87

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 7.3e-07
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 132 vllfflaqlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslll 192
                 + +f+++ ++ G+G+++iy+  +    + ++kk+  l++g++y++ ++G a G +++++++
  EEA19201.1 141 FPVFIVGRVITGLGSALIYSTQTIIALELSSKKRRGLLIGCVYTTVTVGIAAGAIIAGAMA 201
                 349*****************9999999**************************99999875 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.00055
                 xxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 337 GvvvipgaalGillgGllvkklklsa.kklaklvlvvsllsllllllllflgCetskvagv 396
                 G v+++   +G+ lgGllv  ++++  k+    +lv+s+l +l +l++++l+ ++s+v  +
  EEA19201.1 349 GGVIMIPTNAGFALGGLLVGWIHIRKaKSYYISSLVISILFMLSCLSIAVLSTPNSSVILY 409
                 5566666788*************986266777889999************99999988755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (568 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       689  (0.0384294); expected 358.6 (0.02)
Passed bias filter:                      297  (0.0165653); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.44
# Mc/sec: 3890.24
//
Query:       EEA19202.1  [L=353]
Description: arabinogalactan endo-1,4-beta-galactosidase GalA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   3.8e-102  341.8   0.0   4.3e-102  341.6   0.0    1.0  1  Glyco_hydro_53  Glycosyl hydrolase family 53


Domain annotation for each model (and alignments):
>> Glyco_hydro_53  Glycosyl hydrolase family 53
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  341.6   0.0  2.4e-106  4.3e-102       1     340 []      23     350 ..      23     350 .. 0.95

  Alignments for each domain:
  == domain 1  score: 341.6 bits;  conditional E-value: 2.4e-106
  Glyco_hydro_53   1 ikGaDisslveleeagvsfknengktqdllkilkdagvnsvRlrvwndpadenkngelegvndldkaikiakrakaaGmkvlldfHYSDtwaDPa 95 
                     ++GaDissl+ +e++ +s+kn+ng   +l +il+++gvn+vR+r+w++p+d        gv+ ld++ ++a r  +aGmk++ld+H+SDtwaDP+
      EEA19202.1  23 YRGADISSLLVEENNHISYKNTNGAGAKLETILASNGVNTVRQRLWVNPSD--------GVYGLDYNRQLAARMVNAGMKIYLDMHFSDTWADPS 109
                     68*************************************************........************************************ PP

  Glyco_hydro_53  96 kQkkPkaWasldteelkkavydyTkdvlkklkeagvlpelVqvGNEinsgllwsegkkenweklakllnsgikavke..vstnikvviHlanged 188
                     +Q++P +W+++d+ +l++++y+yT dv+++++e+++  e+V++GNEi++gllw+ g+++n++++a+ll+s+++++k+   +t++k++iHl+ng++
      EEA19202.1 110 HQTTPSGWSTTDIGTLSWQLYNYTMDVCNSFAEQNIPLEIVSIGNEIRAGLLWPLGSTSNYHNIATLLHSAAWGIKDskLATKPKIMIHLDNGWS 204
                     *****************************************************************************88899************* PP

  Glyco_hydro_53 189 aaskkaifkklskag....vdfDvigvsYYpfwss..tleklksnlkdlasrygkevivvEtsypytlddgdetgnlapkks...elksipatsq 274
                     +++++++++++ ++g    +dfD++gvsYYpf+ s  tl++lks+l+++as++gk +iv+Et++p+         +  p ++   +l+sip++++
      EEA19202.1 205 WSEQSYFYNTVLAEGpllkTDFDLMGVSYYPFYTSsaTLASLKSTLANMASTWGKGLIVAETNWPFA--------CPRPAYAfpsDLTSIPFSAA 291
                     **************77888**************988899****************************........4444443334899******* PP

  Glyco_hydro_53 275 gqatmlrdlielvkavtdskglGvfYWEpawvskgdkalkwkkgssvenqalfd.rngkalpslkvf 340
                     gqat+l+d++++v+    s+glG+fYWEpaw+ ++      + gss++++ l+d +++ +  s++vf
      EEA19202.1 292 GQATFLKDVASIVAGT--SNGLGMFYWEPAWIGNA------GLGSSCSDNLLVDsSTDAFRTSVEVF 350
                     **************96..9*************988......79***********5566667788776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (353 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       281  (0.0156729); expected 358.6 (0.02)
Passed bias filter:                      238  (0.0132746); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 2364.27
//
Query:       EEA19203.1  [L=395]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      4e-91  305.7  29.0    4.6e-91  305.4  29.0    1.0  1  SLC35F    Solute carrier family 35
    8.1e-09   34.9   6.1    1.7e-08   33.8   6.1    1.6  1  CRT-like  CRT-like, chloroquine-resistance transporter-like
     0.0027   17.9  40.7     0.0069   16.6  14.5    2.3  2  EamA      EamA-like transporter family


Domain annotation for each model (and alignments):
>> SLC35F  Solute carrier family 35
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  305.4  29.0   7.7e-95   4.6e-91       2     298 ..      61     356 ..      60     357 .. 0.99

  Alignments for each domain:
  == domain 1  score: 305.4 bits;  conditional E-value: 7.7e-95
      SLC35F   2 tkkllislalGqvlsllitataltskylaekkinaPvlqtflnyvllalvytgillfrrgaeklleilkrkwykylllalvdveanylvvkayqytslt 100
                 t++++i++ lGq+++l   + +++s  l++k++++P++qt+ +y+ll l yt+i++++ g++k++ +l +  ++y++l+++dve+ny++v ay+ytsl+
  EEA19203.1  61 TRDFWIVIILGQMIALANISSSTFSALLSNKGTSIPAFQTLWVYILLNLTYTSITIYKYGFKKWFRLLYTDCWRYFILSFLDVEGNYFMVLAYRYTSLL 159
                 899************************************************************************************************ PP

      SLC35F 101 svqlldcfaipvvlvlswlflkvryrlvkiigvvvcilGvvllvvsdvlagrransgsnpvlGdllvlaGatlyavsnvleeylvkklslvellgllgl 199
                 s++l+  ++i v++v+s++fl++ry++++++gv+v   G++ll+ sd l g +   + ++++Gdl+ l+ +++ya sn++eey+v+k +++e++g++g+
  EEA19203.1 160 SAELFSFWTIIVIVVISFIFLHIRYHITQYLGVFVACGGMGLLIASDYLRGANY-PAADQLKGDLFALLASSIYAFSNMFEEYMVSKRPMYEVIGQMGF 257
                 **************************************************9876.999***************************************** PP

      SLC35F 200 fGaiisaiqlailerkelkaihWdaeiallfvgfalvlfllysllpilikktsatsvnlslltsdlyslliglflfhykvswlyllafvviliGlilys 298
                 +G +i ++q ai++r++ +   Wd +++ + vg+++vlf++y+l+pil++ +sat++n+sllt +++ l+ig+ +fhy v+ ly++afv++++Gl++y 
  EEA19203.1 258 WGMFINGVQCAIFDRGSFNGAVWDGQVGGYIVGYTIVLFIFYTLAPILLRISSATFFNISLLTMNFWGLIIGIQVFHYSVHFLYPIAFVMVVLGLFVYF 356
                 **************************************************************************************************5 PP

>> CRT-like  CRT-like, chloroquine-resistance transporter-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.8   6.1   2.8e-12   1.7e-08      68     182 ..     132     248 ..      66     269 .. 0.83

  Alignments for each domain:
  == domain 1  score: 33.8 bits;  conditional E-value: 2.8e-12
    CRT-like  68 krkFaimgaLDavsgilvvigavstsGslqvllnqaiipitllasllllkerysliqylGAlviilgvvvvlipsllgesse..gnklvfnllllisvi 164
                  ++++i+++LD  + +++v++  +ts     l    +i +++++s+++l+ ry+++qylG +v  +g+ +++ ++ l +++    ++l  +l+ l++  
  EEA19203.1 132 CWRYFILSFLDVEGNYFMVLAYRYTSLLSAELFSFWTIIVIVVISFIFLHIRYHITQYLGVFVACGGMGLLIASDYLRGANYpaADQLKGDLFALLASS 230
                 4789****************************************************************9888888887666533799999999999999 PP

    CRT-like 165 PvalSnvykeiafkevel 182
                  +a+Sn++ e   ++  +
  EEA19203.1 231 IYAFSNMFEEYMVSKRPM 248
                 9*******9988877655 PP

>> EamA  EamA-like transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.3  18.3   0.00082       4.9       7     136 ..      74     203 ..      65     204 .. 0.80
   2 !   16.6  14.5   1.2e-06    0.0069       2     135 ..     220     355 ..     219     357 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.00082
        EamA   7 allaalfwaiyfvlskillrkvspltltfvrfliagillliiallkegkl.aklslkdwllllllgllgtvlafllffyalkktsasnaslitslePvf 104
                 + la +++++   l     ++++ ++++ v +l+     +i++   + k+  +l ++d   +++l++l  v ++++++ a ++ts   a l+++ + ++
  EEA19203.1  74 IALANISSSTFSALLSNKGTSIPAFQTLWVYILLNLTYTSITIYKYGFKKwFRLLYTDCWRYFILSFLD-VEGNYFMVLAYRYTSLLSAELFSFWTIIV 171
                 556666666666666666799999988888888777777777666666664567888888888888655.66778************************ PP

        EamA 105 tlilsvlllgekltlkqllgivlillGvllil 136
                 ++++s+++l+ +  ++q+lg++++  G  l++
  EEA19203.1 172 IVVISFIFLHIRYHITQYLGVFVACGGMGLLI 203
                 **************************998875 PP

  == domain 2  score: 16.6 bits;  conditional E-value: 1.2e-06
        EamA   2 lgillallaalfwaiyfvlskillrkvspl....tltfvrfliagillliiallkegkl..aklslkdwllllllgllgtvlafllffyalkktsasna 94 
                 +g+l+alla+ ++a++ ++  ++++k + +    ++ f+ ++i g+ + i+    +g++  a+++  ++  +++  ++  ++++ l  ++l+ +sa++ 
  EEA19203.1 220 KGDLFALLASSIYAFSNMFEEYMVSKRPMYevigQMGFWGMFINGVQCAIF---DRGSFngAVWDG-QVGGYIVGYTIVLFIFYTLAPILLRISSATFF 314
                 89*************************999555555667777777777555...333333344544.45666666778899****************** PP

        EamA  95 slitslePvftlilsvlllgekltlkqllgivlillGvlli 135
                  + ++++  + li+++ +++ ++ ++  +++v+++lG+++ 
  EEA19203.1 315 NISLLTMNFWGLIIGIQVFHYSVHFLYPIAFVMVVLGLFVY 355
                 **************************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (395 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1198  (0.0668191); expected 358.6 (0.02)
Passed bias filter:                      523  (0.0291706); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.42
# Mc/sec: 2839.37
//
Query:       EEA19204.1  [L=254]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      5e-24   84.7   2.3    3.9e-12   46.6   0.1    2.4  3  Ank_2       Ankyrin repeats (3 copies)
    5.8e-16   57.0   1.3    8.7e-05   22.6   0.0    4.4  4  Ank_3       Ankyrin repeat
    1.7e-14   53.9   1.1    6.5e-10   39.3   0.1    3.2  3  Ank_4       Ankyrin repeats (many copies)
    3.3e-11   43.2   1.1    4.5e-06   26.8   0.1    3.8  4  Ank_5       Ankyrin repeats (many copies)
    1.7e-10   40.9   0.5    0.00052   20.3   0.0    3.8  3  Ank         Ankyrin repeat
  ------ inclusion threshold ------
      0.013   15.4   2.0       0.15   12.0   0.4    2.4  2  F-box       F-box domain
       0.15   12.0   1.1       0.81    9.6   0.4    2.2  2  F-box-like  F-box-like


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.9   0.1   9.4e-14   2.4e-10      27      80 ..      96     155 ..      75     158 .. 0.85
   2 !   46.6   0.1   1.5e-15   3.9e-12       1      74 [.      99     179 ..      99     187 .. 0.86
   3 !    9.6   0.0   0.00054       1.4      30      80 ..     162     233 ..     158     236 .. 0.76

  Alignments for each domain:
  == domain 1  score: 40.9 bits;  conditional E-value: 9.4e-14
       Ank_2  27 ktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadin 80 
                  + +h+Aa+++n e+v+ L+++       d+ gr+pLhyA  +++++++ +Ll+ gad+ 
  EEA19204.1  96 ASLIHLAARENNFELVEVLVQKgfdlnnRDYFGRSPLHYALDYNQEDMAHFLLDAGADVM 155
                 5789****************978675444488*********************99**986 PP

  == domain 2  score: 46.6 bits;  conditional E-value: 1.5e-15
       Ank_2   1 LhlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh.ad...ndgrtpLhyAarsghleivklLle 74 
                 +hlAa+++n+elv+ L+ +g+d+n  + +g+++LhyA  +++++++ +Ll++ ad    +g++ L +Aa++ +l+iv+  +e
  EEA19204.1  99 IHLAARENNFELVEVLVqKGFDLNnrDyFGRSPLHYALDYNQEDMAHFLLDAgADvmqAKGYS-LLIAAENCSLDIVERIIE 179
                 69****999**************97648***********************885555588997.666667999****98886 PP

  == domain 3  score: 9.6 bits;  conditional E-value: 0.00054
       Ank_2  30 LhyAakngnleivklLleh.................adnd.....grtpLhyAarsghleivklLlekgadin 80 
                 L +Aa+n +l+iv+ ++e+                 +d +      + +L +A    +  i++lLl +gad+n
  EEA19204.1 162 LLIAAENCSLDIVERIIEQmetvespfrllqftgfsMD-StvqtiKNLALNAATIRESGAIANLLLGYGADPN 233
                 7789999999*******965566666666666565522.123344889******998889******99***98 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   4.8e-07    0.0012       3      30 ..      96     122 ..      94     123 .. 0.93
   2 !   22.6   0.0   3.4e-08   8.7e-05       2      29 ..     128     154 ..     127     156 .. 0.95
   3 !    6.8   0.0    0.0048        12       5      23 ..     161     179 ..     159     182 .. 0.90
   4 ?    4.2   0.0     0.034        86       5      30 ..     209     233 ..     206     234 .. 0.77

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 4.8e-07
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvn 30 
                  +++hlAar +n+e+v+ L++ kg d+n
  EEA19204.1  96 ASLIHLAARENNFELVEVLVQ-KGFDLN 122
                 589******************.9***98 PP

  == domain 2  score: 22.6 bits;  conditional E-value: 3.4e-08
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadv 29 
                 G++pLh+A+ ++  ++++fLl+  gadv
  EEA19204.1 128 GRSPLHYALDYNQEDMAHFLLD-AGADV 154
                 9*********************.8**98 PP

  == domain 3  score: 6.8 bits;  conditional E-value: 0.0048
       Ank_3   5 pLhlAarsgnleivkfLle 23 
                  L +Aa++++l+iv+ ++e
  EEA19204.1 161 SLLIAAENCSLDIVERIIE 179
                 699**************99 PP

  == domain 4  score: 4.2 bits;  conditional E-value: 0.034
       Ank_3   5 pLhlAarsgnleivkfLlenkgadvn 30 
                 +L  A    + +i+ +Ll  +gad+n
  EEA19204.1 209 ALNAATIRESGAIANLLLG-YGADPN 233
                 5666666677788999999.*****9 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.3   0.1   2.6e-13   6.5e-10       3      55 .]      97     148 ..      95     148 .. 0.97
   2 !   20.6   0.1   1.9e-07   0.00049       2      52 ..     129     175 ..     128     178 .. 0.82
   3 ?    0.2   0.0      0.47   1.2e+03      17      28 ..     222     233 ..     209     239 .. 0.87

  Alignments for each domain:
  == domain 1  score: 39.3 bits;  conditional E-value: 2.6e-13
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +++h aa ++++elv+ L++kg d+n + +  G+++lh+A+  ++ +++++Ll
  EEA19204.1  97 SLIHLAARENNFELVEVLVQKGFDLNNR-DYFGRSPLHYALDYNQEDMAHFLL 148
                 789*************************.***********************8 PP

  == domain 2  score: 20.6 bits;  conditional E-value: 1.9e-07
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilk 52 
                 +++Lhya  +++++++++Ll+ gad+ +q        l iAa + +++i++
  EEA19204.1 129 RSPLHYALDYNQEDMAHFLLDAGADV-MQ---AKGYSLLIAAENCSLDIVE 175
                 89***********************8.66...4666777777877777775 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.47
       Ank_4  17 vrlLlekgadin 28 
                 + lLl +gad+n
  EEA19204.1 222 ANLLLGYGADPN 233
                 67999*****98 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.1   1.7e-09   4.5e-06      17      56 .]      96     135 ..      85     135 .. 0.92
   2 !   22.4   0.1   4.2e-08   0.00011       1      45 [.     114     157 ..     114     167 .. 0.90
   3 ?    1.2   0.0       0.2     5e+02       1      36 [.     147     178 ..     147     184 .. 0.72
   4 ?    1.7   0.0      0.14   3.5e+02      26      48 ..     216     238 ..     201     245 .. 0.71

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 1.7e-09
       Ank_5  17 ntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                  + +h+Aa+ +++++v++L+  g dln +d  G+++l++A
  EEA19204.1  96 ASLIHLAARENNFELVEVLVQKGFDLNNRDYFGRSPLHYA 135
                 5789***********************************9 PP

  == domain 2  score: 22.4 bits;  conditional E-value: 4.2e-08
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnlt 45 
                 L+++g  d+n++d +g +pLh+A  y+  d++ +Ll+ gad ++ 
  EEA19204.1 114 LVQKG-FDLNNRDYFGRSPLHYALDYNQEDMAHFLLDAGADVMQA 157
                 78899.9*****************************999998875 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.2
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl 36 
                 Ll++g adv  + +g    L +Aa++ ++d+v++++
  EEA19204.1 147 LLDAG-ADV-MQAKG--YSLLIAAENCSLDIVERII 178
                 56666.666.33444..6788999999999999988 PP

  == domain 4  score: 1.7 bits;  conditional E-value: 0.14
       Ank_5  26 ygaadvvrlLlargadlnltdsr 48 
                 + +  +++lLl +gad+n + ++
  EEA19204.1 216 RESGAIANLLLGYGADPNWQMKS 238
                 55667888999*****9977766 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.1   0.0   0.00017      0.42       6      31 ..      99     125 ..      96     126 .. 0.91
   2 !   20.3   0.0     2e-07   0.00052       2      29 ..     128     157 ..     127     160 .. 0.88
   3 ?    5.2   0.0     0.012        32      13      28 ..     220     233 ..     205     236 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00017
                 HHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   6 LHlAatngkkriiklLL.hGAnlnald 31 
                  HlAa++++ + ++ L+ +G +ln +d
  EEA19204.1  99 IHLAARENNFELVEVLVqKGFDLNNRD 125
                 6****************77****9887 PP

  == domain 2  score: 20.3 bits;  conditional E-value: 2e-07
                 SBBHHHHHHHHTTHHHHHHHH.TTTST.TC CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnl.na 29 
                 G++PLH+A  +++++++++LL  GA++ +a
  EEA19204.1 128 GRSPLHYALDYNQEDMAHFLLdAGADVmQA 157
                 99*******99**********66***9455 PP

  == domain 3  score: 5.2 bits;  conditional E-value: 0.012
                 TTHHHHHHHH.TTTSTT CS
         Ank  13 gkkriiklLL.hGAnln 28 
                 +   i+ lLL +GA++n
  EEA19204.1 220 A---IANLLLgYGADPN 233
                 4...788999999***9 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.4   5.9e-05      0.15       1      36 [.       1      36 [.       1      38 [. 0.93
   2 ?    2.4   0.1      0.06   1.5e+02       7      22 ..     170     185 ..     167     193 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 5.9e-05
                -HHHHS-HHHHHHHHHTS-HHHHHHHCTT-HHHHHH CS
       F-box  1 ftlsrLPsevlrhILerLplsdllalrrVSkgwril 36
                +++ +LP +v++ +  +L+ +++ +l rVS ++  l
  EEA19204.1  1 MPFIELPVDVILSVTAFLSYVEIASLIRVSQSLAHL 36
                7899**************************999876 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.06
                 -HHHHHHHHHTS-HHH CS
       F-box   7 PsevlrhILerLplsd 22 
                 ++++++ I+e++++++
  EEA19204.1 170 SLDIVERIIEQMETVE 185
                 789*********9986 PP

>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.4   0.00031      0.81       2      43 ..       4      43 ..       3      47 .. 0.89
   2 ?    0.5   0.0      0.23   5.9e+02      30      46 ..      70      85 ..      69      87 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00031
  F-box-like  2 srLPdEiLlqIFsyLppsdLlrlalVCrrWrrvaldtplLWr 43
                  LP +++l +  +L+  ++++l +V+ + + +    p+L++
  EEA19204.1  4 IELPVDVILSVTAFLSYVEIASLIRVSQSLAHLL--LPYLYN 43
                57*************************9999998..568886 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.23
  F-box-like 30 rWrrvaldtplLWrrlv 46
                rWr++a  + +++ ++v
  EEA19204.1 70 RWRSLAILN-YFYETPV 85
                8*****887.9998887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (254 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       492  (0.0274416); expected 358.6 (0.02)
Passed bias filter:                      456  (0.0254337); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.48u 0.23s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 1843.04
//
Query:       EEA19205.1  [L=214]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.6e-09   37.3   0.0    4.5e-09   36.6   0.0    1.4  1  Acetyltransf_1   Acetyltransferase (GNAT) family
    1.2e-08   34.9   0.0    7.1e-08   32.5   0.0    1.9  2  Acetyltransf_10  Acetyltransferase (GNAT) domain
    1.1e-07   32.2   0.0      9e-07   29.2   0.0    2.0  2  Acetyltransf_7   Acetyltransferase (GNAT) domain
    0.00055   20.0   0.0       0.02   15.0   0.0    2.3  2  Acetyltransf_9   Acetyltransferase (GNAT) domain


Domain annotation for each model (and alignments):
>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.6   0.0     1e-12   4.5e-09      37     117 .]      67     190 ..      30     190 .. 0.75

  Alignments for each domain:
  == domain 1  score: 36.6 bits;  conditional E-value: 1e-12
                     EEEET..TEEEEEE......................................EEEEEET.......TSTTEEEEEEEEESGGGTTSSHHHHHHHH CS
  Acetyltransf_1  37 vaeed..geliGfi......................................sllkipd.......ekggvayieslaVspeyrgkGlGsaLlea 84 
                     va +d  ++++G++                                      ++l ++           +v+ ++sl V+p++++kG+G++Ll+ 
      EEA19205.1  67 VAVDDdkNKIVGYAiwevpvsssdegeneeegvmlpplaqegidkapfmelrRILEDDVreqfgdkGTVDVWTLDSLGVHPNHQKKGIGRMLLDW 161
                     344443577999998888888888888888888888888887777777666633333336666666556889999******************** PP

                     HHHHHHHT..TESEEEEEEETTEHHHHHHHHHTTE CS
  Acetyltransf_1  85 leeraree..gikkivlaveedndaairlYeklGF 117
                      +e+a ++  g+   +l   +   a  ++Y+  GF
      EEA19205.1 162 GIEEASKQgrGC---YL---VATPAGLPVYTAAGF 190
                     ***999996555...77...456778****99999 PP

>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0      0.21   9.2e+02      29      46 ..      62      80 ..      44      87 .. 0.66
   2 !   32.5   0.0   1.6e-11   7.1e-08      53     125 ..     139     208 ..     126     209 .. 0.90

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.21
  Acetyltransf_10 29 gealllva.eeggkivGvi 46
                     + ++++++ ++++kivG++
       EEA19205.1 62 STVVMVAVdDDKNKIVGYA 80
                     3444444414459999997 PP

  == domain 2  score: 32.5 bits;  conditional E-value: 1.6e-11
  Acetyltransf_10  53 hisllfVdpeyrgqGigkaLleaveeeaekdgikleltvnaspyavpfYeklGFkavgeeqeenGirfvpMek 125
                       +  l V+p+++++Gig++Ll+  +eea+k+g +    + a+p+  p+Y   GF++v     + G  +v+M+k
       EEA19205.1 139 TLDSLGVHPNHQKKGIGRMLLDWGIEEASKQGRG--CYLVATPAGLPVYTAAGFEDVRVLDIF-GTPHVSMRK 208
                      567899**********************999766..99*******************988877.899999997 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0      0.15   6.8e+02       5      19 ..      65      81 ..      61     107 .. 0.76
   2 !   29.2   0.0     2e-10     9e-07      16      75 ..     133     191 ..     110     192 .. 0.69

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.15
                    EEEEEET..TEEEEEEE CS
  Acetyltransf_7  5 vfVaedd..gkivGfia 19
                    v Va dd  +kivG+++
      EEA19205.1 65 VMVAVDDdkNKIVGYAI 81
                    556766678999**875 PP

  == domain 2  score: 29.2 bits;  conditional E-value: 2e-10
                     EEEEEEEESTCTEEEEE-GGGTTSSHHHHHHHH...TT....SEEEEEEEEE.THHHHHHHHHHTTEE CS
  Acetyltransf_7  16 GfialslldaeitrlaVdpeyrgkGiGraLlea...ae....kgiileqlel.naekaikfYeklGFe 75 
                     G++ ++     +  l V+p++++kGiGr Ll+    ++    +g+     +l ++++ ++ Y   GFe
      EEA19205.1 133 GTVDVWT----LDSLGVHPNHQKKGIGRMLLDWgieEAskqgRGC-----YLvATPAGLPVYTAAGFE 191
                     4333333....3459*****************7554115545666.....44233466889*999998 PP

>> Acetyltransf_9  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.0     0.026   1.2e+02       2      29 ..       5      39 ..       4      82 .. 0.66
   2 !   15.0   0.0   4.5e-06      0.02      71     126 ..     135     191 ..     125     193 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.026
                    EEEE-GGGHHHHHHHHHHHTT----H......... CS
  Acetyltransf_9  2 irelteedldevlellkyaFqdeespl.......e 29
                    +r++ e+dl  ++++  +aF  + + +       +
      EEA19205.1  5 LRPASEADLATIVDVSTAAFPPDVDTIvrhlfpgD 39
                    79999999999999999999988877655555440 PP

  == domain 2  score: 15.0 bits;  conditional E-value: 4.5e-06
                     EEEEEEEEEEE-CCGTTS-HHHHHHHHHHHHHHHTT--.EEEE--SSHHHHHTTT-E CS
  Acetyltransf_9  71 lkaagvtgVavapehrgrgvlskLlaraleemreegqp.lsllfPssipiYrrfGye 126
                     +++  + + +v+p+h+++g+ + Ll+  +ee+ ++g     + +P+  p+Y   G+e
      EEA19205.1 135 VDVWTLDSLGVHPNHQKKGIGRMLLDWGIEEASKQGRGcYLVATPAGLPVYTAAGFE 191
                     5555666889***********************997651556778999*****9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (214 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       226  (0.0126053); expected 358.6 (0.02)
Passed bias filter:                      218  (0.0121591); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1576.87
//
Query:       EEA19206.1  [L=414]
Description: checkpoint kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.4e-41  140.5   0.0    9.8e-41  139.9   0.0    1.2  1  Pkinase      Protein kinase domain
    4.4e-22   78.6   0.0    6.8e-22   78.0   0.0    1.2  1  Pkinase_Tyr  Protein tyrosine kinase
  ------ inclusion threshold ------
       0.01   15.1   0.0        0.1   11.9   0.0    2.1  2  Kinase-like  Kinase-like


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.9   0.0   1.6e-44   9.8e-41       3     198 ..     137     359 ..     136     399 .. 0.85

  Alignments for each domain:
  == domain 1  score: 139.9 bits;  conditional E-value: 1.6e-44
                 EEEEEEEESSEEE......EEEEETTTTEEEEEEEEECHCHCHHHH..HHHHHHHHHHHHHSCTTB--EEEEEEE.SSEEEEEEE--TTEBHHHHHHHH CS
     Pkinase   3 kleklGeGsfGkV......ykaveketgkivAvKkikkekakkkke..kkvlrEikilkklkhpnivrlyevfee.kdelylvleyveggeladllerk 92 
                 ++e++G+Gs+G V       ++ + + g+ +AvK++++++++++k+  k+v +E  i  +l+h ni+r y+ +++ + +++ ++ey++gg++ ++++ +
  EEA19206.1 137 NKEQIGRGSSGIVtvtfrpHSVDHPSGGQLFAVKRFSQREKDSTKKhlKRVGAEFCISSSLQHANIIRTYDLVQDtDGSFCQIMEYCSGGDVYTRVRSQ 235
                 689*********94443333455677899**********999999999**************************9566899****************** PP

                 SS--HHHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCS.....BCTTTSCGGGS-HHHH...........TTSCB. CS
     Pkinase  93 gslseeeakkiakqilegleylHskgiiHrDlKpeNiLidekgelKitDFGlakelesssk.....ltsfvgtseYlAPEvl...........keney. 174
                 g+l  +ea+ ++kq+l+gl+ylH  g+ HrDlKp+N+L+  +g lKi+DFG a+ ++   +      +  +g+  Y++PE             +++ y 
  EEA19206.1 236 GKLCGTEANCYFKQLLRGLDYLHTTGVAHRDLKPDNLLLTCRGCLKIADFGNAECVRLPWEktsrlSSGLCGSFPYISPEQYvtldyrdkdspSSRYYy 334
                 ******************************************************9987666677877889**********8778999998877444444 PP

                 .SHHHHHHHHHHHHHHHHHSS-STT CS
     Pkinase 175 .skkvDvWslGvilyelltgkppfs 198
                   +++DvW++G+i + + tg++ ++
  EEA19206.1 335 dARAADVWAAGIIYLDMRTGRHAWR 359
                 7899*****************9887 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.0   0.0   1.1e-25   6.8e-22       4     203 ..     138     355 ..     136     387 .. 0.82

  Alignments for each domain:
  == domain 1  score: 78.0 bits;  conditional E-value: 1.1e-25
                  EEEEEEESSEEEEEEEEET..TTTSSEEEEEEEEESTTSSHHH...HHHHHHHHHHHHTS-BTTB--EEEEEE.SSSSEEEEEE--TTEBHHHHHHHT CS
  Pkinase_Tyr   4 gkklGeGafGkVvegtlkg..ekekkevkVavKtlkeeateee...keelleeakimkklkhpnivkllgvct.keepllivteyvkgGdLlkfLrkk 95 
                  ++++G+G+ G V      +  ++ +  +  avK ++++ ++++    +++  e  i ++l+h ni++ + ++   +++ + ++ey++gGd+ + +r++
   EEA19206.1 138 KEQIGRGSSGIVTVTFRPHsvDHPSGGQLFAVKRFSQREKDSTkkhLKRVGAEFCISSSLQHANIIRTYDLVQdTDGSFCQIMEYCSGGDVYTRVRSQ 235
                  789*******9987766667788889999*****976665555011555566999******************78889******************98 PP

                  CTTTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEETTEEEE-STTTHEET..TTSSEEEETTSSTSGGGGS-HHHHHHSE.......... CS
  Pkinase_Tyr  96 ekekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsenkvvkisDfGLardi..ekddeyvkkeeaklpvkWmapEslkekk.......... 181
                     kl+ ++  ++  q+ +G++yL++  + Hrdl   N Ll+ + + ki+DfG a+ +    +++ + +++   ++ +++pE   +            
   EEA19206.1 236 --GKLCGTEANCYFKQLLRGLDYLHTTGVAHRDLKPDNLLLTCRGCLKIADFGNAECVrlPWEKTSRLSSGLCGSFPYISPEQYVTLDyrdkdspssr 331
                  ..999999***********************************************99932334444666666778999****8877666678889888 PP

                  ...EEHHHHHHHHHHHHHHHHTTSS CS
  Pkinase_Tyr 182 ...ftsksDvWsfGvllwEiftlge 203
                        ++DvW+ G++   + t g+
   EEA19206.1 332 yyyDARAADVWAAGIIYLDMRT-GR 355
                  7633467899999999888877.55 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0     0.046   2.7e+02      37      93 ..     164     212 ..     151     220 .. 0.74
   2 ?   11.9   0.0   1.7e-05       0.1     151     189 ..     248     286 ..     227     293 .. 0.88

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.046
  Kinase-like  37 geplavkvfllps.easkkdlerlkeqelairllrgknpeqAkdhlrlllpfdlvkiq 93 
                  g+ +avk f+  + +  kk l+r+  +e+ i            +h  ++  +dlv+++
   EEA19206.1 164 GQLFAVKRFSQREkDSTKKHLKRV-GAEFCISS--------SLQHANIIRTYDLVQDT 212
                  788999999999944555666665.56677776........45677788888888876 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 1.7e-05
  Kinase-like 151 lqlirlaanLqakglvhgkftvdnllldekgglmlggft 189
                   ql+r   +L+  g+ h ++++dnlll  +g l++ +f+
   EEA19206.1 248 KQLLRGLDYLHTTGVAHRDLKPDNLLLTCRGCLKIADFG 286
                  57889999*****************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (414 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       513  (0.0286129); expected 358.6 (0.02)
Passed bias filter:                      479  (0.0267165); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 2773.76
//
Query:       EEA19207.1  [L=258]
Description: 4-carboxymuconolactone decarboxylase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-06   27.7   0.0    4.7e-06   26.6   0.0    1.6  1  CMD       Carboxymuconolactone decarboxylase family


Domain annotation for each model (and alignments):
>> CMD  Carboxymuconolactone decarboxylase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.6   0.0   2.6e-10   4.7e-06       8      63 ..      98     152 ..      91     155 .. 0.80

  Alignments for each domain:
  == domain 1  score: 26.6 bits;  conditional E-value: 2.6e-10
                 HHHHHHHCCGSSTS-HHHHHHHHHHHHHHTT-HHHHHHHHHHHHHTT--HHHHHHH CS
         CMD   8 talreallareggLdpkereLialavsaangceyCvdaHtraAleaGvteeeiaev 63 
                 + l +a+   +   +    eL   +v+++ng +y+++aH+  Al+aGvt+ +++ev
  EEA19207.1  98 NSLLGAIRT-QAVMPQDILELSVCRVAILNGAVYEWNAHAPLALKAGVTAAQLQEV 152
                 555555555.55556666799999******************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (258 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       453  (0.0252663); expected 358.6 (0.02)
Passed bias filter:                      399  (0.0222544); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.23s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1872.31
//
Query:       EEA19208.1  [L=371]
Description: carboxy-cis,cis-muconate cyclase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.1e-22   79.9   0.0    2.8e-22   79.4   0.0    1.2  1  Lactonase  Lactonase, 7-bladed beta-propeller


Domain annotation for each model (and alignments):
>> Lactonase  Lactonase, 7-bladed beta-propeller
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.4   0.0   1.6e-26   2.8e-22       2     318 ..      16     343 ..      15     357 .. 0.77

  Alignments for each domain:
  == domain 1  score: 79.4 bits;  conditional E-value: 1.6e-26
                 EEEEEGGSSS.TEEEEEEEETTTS-EEEEEE.EEESS--.-SEEE-TTSSEEEEEET.STTTEEEEEEEETTTTEEEEEEEEE.SSS-EEEEEE-TTSS CS
   Lactonase   2 lyvGtytkgeskgiytlkldtetgkltplel.vaelenP.syLalspdgktlYavnetgeeggvsafaidkdsgeltllnkvssegaspchlsvdedgk 98 
                 l++Gt t    + iyt+ +d+++  l+ +++ ++  ++P s+++++ ++k +Y +  +    + s+f++ + + e+   ++ +  g++p+  s d + +
  EEA19208.1  16 LMIGTWTP--PGRIYTVAFDDQELTLKLVKKtMIPEDEPiSWMTFDHAKKNIYGAAMK----KWSSFSVRSPT-EIVHEGSHQ-MGGDPMANSADTNTR 106
                 78999996..9*******************98777777769************99765....78888888774.555555555.455555555566666 PP

                 EEEE.EETT.............TTEEEEEEB.TTSEBESECEEEE.....SSTTT-SSTTEEEEEE-TTSSEEEEEETTTTEEEEEEE.-TTS-EEEEE CS
   Lactonase  99 llav.AnYs.............ggsvsvfpldadgslkeasqvlkhegsgpnperqesphaHsvvldpdgkfllvpDLGtDrvrvykldkatgkltepa 183
                  ++v A ++             +g  +vf++ ++g++++ +q ++          + ++ +H +v+dp++ +l++ D G+ ++ + k d++tg lt + 
  EEA19208.1 107 AIFVlAGHKppynvygnpfykhAGFGNVFSVTESGKIDKNVQNFEI---------DPHSGIHGMVFDPTETYLYSADMGANKIWTHKKDPETGLLTLVD 196
                 5555255446666777777777888889999999999998888754.........33689*************************************** PP

                 EE.E-STT--EEEEEE-TTSSEEEEEETTTTEEEEEEEE-TTT.EEEEEEEEESS-TS.S-S---EEEEEE.-TTSSEEEEEETS.....STEEEEEEE CS
   Lactonase 184 sv.klppgsGPRHlaFhpdgkiaYvvnELsstvsvfsydeatg.aleelqtvstlpeg.ftgknsaaeIrl.spdgkflyvSnRg.....adsiavfav 273
                 s+ + +pg+ PR +a hp+g+++Y + E  ++++v+ +de+    +     ++ +p+g    ++  a+++  +++gk+l++ +R+     +  i+ f++
  EEA19208.1 197 SIdAPAPGDHPRWVAMHPSGHYLYALMEAGNRLAVYVIDEKRHvPVFTRMIYPLVPPGlPPRNKYRADVVFpTKSGKYLFATSRSnhndiHGYISAFRL 295
                 **56679********************************88776555566788899974556668899876489************999999999**99 PP

                 -TTT--EE...EEEEEE-SSS.--EEEE.-TTSSEEEEEETTTTEEEEE CS
   Lactonase 274 deadgtlt...lveevstegkfPRdfal.dpsgklllvanqksdnvtvf 318
                  + +g+++   +++ +st g +    +  d s+++++ ++ +++ v+++
  EEA19208.1 296 GP-EGNIEkqlFINPTSTSGGHSNAVSPcDWSDEWIALCDDQDGFVEIY 343
                 55.5788722233444555544444442355555555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (371 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       305  (0.0170115); expected 358.6 (0.02)
Passed bias filter:                      294  (0.016398); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2564.55
//
Query:       EEA19209.1  [L=309]
Description: hypothetical protein PMAA_014690 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.7e-24   84.6  15.2      8e-24   84.4  15.2    1.1  1  Frag1     Frag1/DRAM/Sfk1 family
  ------ inclusion threshold ------
       0.12   12.2   0.0       0.38   10.6   0.0    1.8  2  Phage_C   Phage protein C


Domain annotation for each model (and alignments):
>> Frag1  Frag1/DRAM/Sfk1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.4  15.2   8.9e-28     8e-24       1     217 [.      11     291 ..      11     293 .. 0.91

  Alignments for each domain:
  == domain 1  score: 84.4 bits;  conditional E-value: 8.9e-28
       Frag1   1 yffllpliafilwlgmliamlvcavvqgpvdyvfmhkeqflPyISdigatnpeslffslalnlglflvilvallrfqr..................... 78 
                 + f+lp i+++ wl+ml +++  + + g+ +yv+ ++ q++ +ISdiga+++++ f++ a +    ++ ++++ ++                       
  EEA19209.1  11 WAFILPTITVASWLAMLGTLVGSWFASGQPRYVSEEDTQTIAFISDIGAQHLKPVFIAGASISMTTYIPSLIVYFYYMsparvplssssesitranslp 109
                 579*************************888**999**********************998888888877777777778******************** PP

       Frag1  79 ..............lpplatksern.........lnfaalvlgligalglllvsifstaeyhsvHlvgavvffvfgflyvllqtalyykmgrhy..... 149
                                +++ +++e++         +  +++++ liga +l+l++if+ta+y s H+      + + +l +l+ ++ +    r+y     
  EEA19209.1 110 ptsiystpppsslaSQHHLQQEEKWhqsllsqigIPLLSILFSLIGATSLVLLTIFDTARYTSAHQLLLPTSICSHILGCLILCFWTVICFRQYkaqiq 208
                 ************9944444444444566699999********************************99988888888888888888888888888889* PP

       Frag1 150 .....................vwnkstisfrlkvvllilavvlailfgvffvrhkkkcgygayslsAifEWllafwfiiffltfsvDFy 217
                                      + + ++ s+ +k+v++++ + l+ lf+v+    k          +A+ EW+++++f++++l+++vD++
  EEA19209.1 209 htkysggiysgdkftlelympRIPIFRPSLVIKAVIIAIEFGLVTLFAVMTWWLKTF------DQAAVIEWVVVLTFGGYMLCLIVDLW 291
                 ****************************************************97776......99**********************96 PP

>> Phage_C  Phage protein C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   4.3e-05      0.38      32      46 ..      22      36 ..      16      49 .. 0.84
   2 ?   -3.1   0.0       0.8   7.2e+03      28      35 ..     129     136 ..     122     139 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 4.3e-05
     Phage_C 32 kwlnmlGtfvkdwfr 46
                 wl mlGt+v  wf 
  EEA19209.1 22 SWLAMLGTLVGSWFA 36
                6*************5 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 0.8
     Phage_C  28 ldeekwln 35 
                  +eekw +
  EEA19209.1 129 QQEEKWHQ 136
                 57999975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       789  (0.0440069); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.43u 0.24s 00:00:00.67 Elapsed: 00:00:00.38
# Mc/sec: 2465.47
//
Query:       EEA19210.1  [L=159]
Description: hypothetical protein PMAA_014700 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (159 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       352  (0.019633); expected 358.6 (0.02)
Passed bias filter:                      315  (0.0175693); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.27s 00:00:00.69 Elapsed: 00:00:00.44
# Mc/sec: 1095.17
//
Query:       EEA19211.1  [L=234]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.7e-07   28.8   0.0      5e-06   26.5   0.0    2.0  1  Acetyltransf_10  Acetyltransferase (GNAT) domain
    5.5e-06   26.6   0.0      1e-05   25.7   0.0    1.7  1  Acetyltransf_1   Acetyltransferase (GNAT) family
     0.0001   22.2   0.0    0.00021   21.2   0.0    1.4  1  FR47             FR47-like protein
    0.00012   22.5   0.0    0.00023   21.5   0.0    1.7  1  Acetyltransf_7   Acetyltransferase (GNAT) domain


Domain annotation for each model (and alignments):
>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.5   0.0   1.1e-09     5e-06      47     112 ..     144     210 ..      87     214 .. 0.81

  Alignments for each domain:
  == domain 1  score: 26.5 bits;  conditional E-value: 1.1e-09
  Acetyltransf_10  47 elrdgs...hisllfVdpeyrgqGigkaLleaveeeaekdgikleltvnaspyavpfYeklGFkavgee 112
                      ++r+++    +  l  +p + ++Gig++L++  ++ a+++ i  ++ v + p+a ++Y +lGFk v+ +
       EEA19211.1 144 RIRRDGpflTLDYLTTNPVFWRRGIGSMLVQSGLKVADQHAI--KTYVMSEPAALKLYLNLGFKLVETV 210
                      44333357788889999********************77755..6*******************98765 PP

>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.7   0.0   2.3e-09     1e-05      37     117 .]     115     204 ..      24     204 .. 0.83

  Alignments for each domain:
  == domain 1  score: 25.7 bits;  conditional E-value: 2.3e-09
                     EEEETTEEEEEEEEEEEET.............TSTTEEEEEEEEESGGGTTSSHHHHHHHHHHHHHHHTTESEEEEEEETTEHHHHHHHHHTTE CS
  Acetyltransf_1  37 vaeedgeliGfisllkipd.............ekggvayieslaVspeyrgkGlGsaLlealeerareegikkivlaveedndaairlYeklGF 117
                     ++ ++g+ iG+ s+++                 +g+   ++ l  +p ++++G+Gs+L++  ++ a ++ ik  ++   ++  aa +lY  lGF
      EEA19211.1 115 ACTKNGRAIGMKSGSMMSYrsapleavdarirRDGPFLTLDYLTTNPVFWRRGIGSMLVQSGLKVADQHAIKT-YV---MSEPAALKLYLNLGF 204
                     24567899999977777777778888888888889999999****************************9988.66...7899******88999 PP

>> FR47  FR47-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.0   4.6e-08   0.00021       5      81 ..     133     208 ..     132     212 .. 0.87

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 4.6e-08
                 EETTT--EEEEEEE-TT..SSEEEEEE-GGG-SSSHHHHHHHHHHHHHHHS-S-EEEEEETT-HHHHHHHHHHT-EEEE CS
        FR47   5 yrkelgelaawilrkdg..gelgalqvlpehrrrGlgsrlvkalakeiaergktvllvvvasNtpsirlyeklGfekie 81 
                 yr+++ e+++ ++r+dg    l  l ++p + rrG gs lv++   ++  ++++++   v s+ ++ +ly  lGf++ e
  EEA19211.1 133 YRSAPLEAVDARIRRDGpfLTLDYLTTNPVFWRRGIGSMLVQS---GLKVADQHAIKTYVMSEPAALKLYLNLGFKLVE 208
                 56778899999****993344568*****************96...889999999999*****************9874 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.0   5.2e-08   0.00023      27      75 ..     154     205 ..      88     206 .. 0.73

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 5.2e-08
                     TEEEEE-GGGTTSSHHHHHHHH...TT.SEEEEEEEEE.THHHHHHHHHHTTEE CS
  Acetyltransf_7  27 itrlaVdpeyrgkGiGraLlea...ae.kgiileqlel.naekaikfYeklGFe 75 
                     + +l ++p + ++GiG+ L++    ++ ++ i  ++++ ++++a+k+Y  lGF+
      EEA19211.1 154 LDYLTTNPVFWRRGIGSMLVQSglkVAdQHAI--KTYVmSEPAALKLYLNLGFK 205
                     3448899*************953331132212..3456555599*********8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (234 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       363  (0.0202465); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 1547.05
//
Query:       EEA19212.1  [L=545]
Description: benzoate 4-monooxygenase cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-52  178.5   0.0    2.5e-52  178.2   0.0    1.1  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  178.2   0.0   1.4e-56   2.5e-52       2     442 ..     102     516 ..     101     523 .. 0.89

  Alignments for each domain:
  == domain 1  score: 178.2 bits;  conditional E-value: 1.4e-56
                 -SES.EHHCCHCHHHHTT.TCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGH.HHHHH CS
        p450   2 pgpt.plplvgnllqlgr.keelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfang.ekwkk 97 
                 ++++ +l  +++l+++   k   +++l++l+++yg+ +r   g+++ v + +p a   vl+  +  + g  + + ++     +++++v +++  e ++k
  EEA19212.1 102 GPFNaRLSKFWSLKKVVDsKLRWWKILDRLHEQYGDYVRT--GPRELV-IFDPAALTPVLGFAS--ITG--KGP-FYD----SMETSVNTSRDkEFHRK 188
                 555557788899998888788899************9875..666665.667********9994..444..344.554....57788888888577777 PP

                 HHHHHHHHHTSHSTT.THHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCCC CS
        p450  98 lRrfltptltsfgkl.sleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelssllskssvqllllf 195
                  R++  +++ ++  l  + +++ee + +l+e+++k+ g++  + + e+  ++ +dv++ ++Fg +++ l+ +++  +  + +++ + +  +   lll+ 
  EEA19212.1 189 RRKIWDNAFKKS--LsDYGPRIEEFTGQLIERIEKNDGKP--ILLNEICIHYSYDVMSALAFGDPMGFLKGDSNDVANSVLDNIQKGV--DAIGLLLHV 281
                 777777777755..779***********************..****************************999988888888887777..66789**** PP

                 HHHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHH CS
        p450 196 pllkylptkllrklkeavkklkdlldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPe 294
                 p+l   +t +   +  + ++ +++ ++l+  r+e  +++     d+  +ll+++   +++    ++ l+ ++  + +aG+dTt+++l++ + +La +Pe
  EEA19212.1 282 PWLMGTLTTFSWAIGPM-RQWNEYSEQLVVLRKEMKNPK----PDLFGHLLDNT---EDT-ATGRALLNSECRLIVGAGSDTTATALTFLFVQLALYPE 371
                 *9999999999999977.99*************999988....8*********7...333.57899999****************************** PP

                 HHHHHHHHHHHHCCTTTT-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS.CEEETTEEE-TT-EEEEEHHHHHT-TTTSSSTTS--GGGGB-TT CS
        p450 295 vqeklreEidevlgdkreptyddlqklpyldavikEtLRlhpvvplllpRevtk.dvvirgylipkGtevivnlyalhrdpevfpnPeeFdpeRFldek 392
                    +lreE+d ++  +    y++    p+lda+i+E++Rlhp v ++ +Re++   ++i++ +ip +t+++++ y l rd+  f  ++ F peR+ ++ 
  EEA19212.1 372 WILRLREEMDPIFSAS---GYECTRTYPVLDAIINESMRLHPSVFFGSQRETPPqGMQIGETFIPGNTIISIPGYQLARDERNFVLANDFLPERWYSKP 467
                 *************775...4*******************************9754*******************************************9 PP

                 SCTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTS CS
        p450 393 gnskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetd 442
                 + +  ++ a++PF  Gp nC G++lA+mel+ ++a+++++F+v+++++++
  EEA19212.1 468 ELT-INKTAHMPFLIGPFNCAGRNLAMMELRSVVARVVHEFDVSFPKGVE 516
                 955.****************************************988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (545 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       345  (0.0192426); expected 358.6 (0.02)
Passed bias filter:                      291  (0.0162307); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.31s 00:00:00.87 Elapsed: 00:00:00.48
# Mc/sec: 3386.66
//
Query:       EEA19213.1  [L=351]
Description: integral membrane protein (Pth11), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (351 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       702  (0.0391544); expected 358.6 (0.02)
Passed bias filter:                      241  (0.0134419); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 2352.09
//
Query:       EEA19214.1  [L=794]
Description: beta-glucosidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      1e-49  169.3   0.1    1.8e-49  168.5   0.1    1.4  1  Glyco_hydro_3_C  Glycosyl hydrolase family 3 C-terminal domai
    9.3e-36  123.8   0.0    1.9e-35  122.8   0.0    1.4  1  Glyco_hydro_3    Glycosyl hydrolase family 3 N terminal domai
      5e-21   74.6   0.0    1.1e-20   73.5   0.0    1.6  1  Fn3-like         Fibronectin type III-like domain


Domain annotation for each model (and alignments):
>> Glyco_hydro_3_C  Glycosyl hydrolase family 3 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  168.5   0.1   2.9e-53   1.8e-49       2     204 .]     394     644 ..     393     644 .. 0.89

  Alignments for each domain:
  == domain 1  score: 168.5 bits;  conditional E-value: 2.9e-53
                      EEEEEGSS--S-S-STEEEEEESGGGS.............SS-SS-BSSS----S---HHHHHHHHHHH...............-HHHHHHHHH CS
                      xxxxxxxxxxxxxxxxxxxxxxxxxxx.............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.............xxxxxxxxxxx RF
  Glyco_hydro_3_C   2 VLLkNennlLPLkkklkkiaviGpnad.............etlklGggsgtvtvsylvsplegirerles.............eegideaveaa 69 
                      VLLkN +n+LPL+k++k+i v+G++a              + l  Gggsgt +++ lvsple+i+ r ++             +++++   +  
       EEA19214.1 394 VLLKNTDNTLPLSKNIKRISVFGNDAAdlsggpydpsntnGVLAVGGGSGTGRFTNLVSPLEAIKYRNPQalvqyvtdntlltQDTSRTLDTLY 487
                      9**********************99999***********99***************************99************9999999999** PP

                      HHTSEEEEEEEES...SB-TTSCSGHHSSTTHHHHHHHHHHTT..SSEEEEEEESSGG--TTTGTTTEEEEEE-S--GCCHHHHHHHHHTTSS- CS
                      xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_3_C  70 keaDvavvvvgedpeiegEgvDrtdlalpeaqdelikavaaan..knvvvvlqsggpvavepwkeenvkAilaawlpGqegGtaiadvLfGdvn 161
                        aDv++v++++    ++Eg+Drt+l  ++++ +l++av + +  +++vv+l+s g+  + +++++n+++i+aa+lpG+++G++i+dvLfGdvn
       EEA19214.1 488 PPADVCLVFLKSY---ATEGYDRTTLIADGNSTALVEAVTSYGgcPSTVVILHSVGANLLPWAHNANITGIIAAHLPGEQAGNSIVDVLFGDVN 578
                      *************...************************7655599*************777999**************************** PP

                      --B--SS-EESSSGGG..................................S.-----SETTTT-BCH CS
                      xxxxxxxxxxxxxxxx..xx.xxxxxxxx....................xx.xxxxxxxxxxxxxxx RF
  Glyco_hydro_3_C 162 PsGkLpvtfpksledl..pd.dyyeekdt....................yk.fegtplYpeGlglsY 204
                      PsGkLp+t++ +++d+  p+ ++++ + +                     + ++ tp Y++G+glsY
       EEA19214.1 579 PSGKLPYTIAYNESDYnaPTvNFTDVD-NsdaniwqsnfteglmidyrhFDyNNITPQYEFGYGLSY 644
                      ****************54446555444.123456777888888888554222344555*******99 PP

>> Glyco_hydro_3  Glycosyl hydrolase family 3 N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  122.8   0.0   3.1e-39   1.9e-35      86     318 ..      91     327 ..      79     327 .. 0.86

  Alignments for each domain:
  == domain 1  score: 122.8 bits;  conditional E-value: 3.1e-39
                    ---S-HHHHHHHT-HHHHHHHHHHHHHHHHHHT--EE---B--.---STTSSSGGGSS-SSHHHHHHHHHHHHHHHHHTT-EEEEEEETTGTT-SS CS
  Glyco_hydro_3  86 tlfPsalalaatssldlikelgriiakelralgididfaPvvd.vnrdprngigvrsFsedpelvaalaaamvkGlqgagvaatvKHFpghGdgav 180
                     +fP+ ++ aat+++dl+++ g  +a+e    g ++ ++Pv+  ++r    g++ ++Fs dp+l++   a+++kG+q+++v a++KH++g  + + 
     EEA19214.1  91 SVFPAGVSVAATWDRDLLYQRGVEMAAEFKGKGAHVALGPVAGpLGRSALGGRNWEGFSPDPYLTGISFAETIKGMQSQKVQACGKHYIGNEQETK 186
                    79***************************************97477777777**************************************855433 PP

                    E.........TTTSEEB----HHHHHHTTHHHHHHHHHTT-SEEEE---B-TTT---BGGG-HHHHIIIIIIIS---SEEEES-TTSHHHHCCS-H CS
  Glyco_hydro_3 181 d.........shkelptvdhseeelrevdlvpfqaaieagvdsVMtaHvqfpaldgtpatgskklltdvLRkelGFdGvvvsDalamkeiadrggk 267
                              +++e + ++++ + l+e +l pf + ++ag+ s+M +   ++ +++t a  ++k l ++L++elGF+G v+sD+       ++   
     EEA19214.1 187 RnpstypngtTEQEAVSSNIDDRTLHELYLWPFYEGVKAGMASIMCS---YNRINETYACQNSKTLNGILKEELGFQGYVMSDWG-----GTH--- 271
                    311111111145566777889999***********************...**********************************9.....333... PP

                    HHHHHHHHHHT-SBEES-S---SG.......HHHHHHHHHTTSS-HHHHHHHHHHHHH CS
  Glyco_hydro_3 268 eeavvlaLkAGvDilLvpeertse.......ikalkkavkeGeltearidesvrrvlr 318
                          aL +G+D+ +  + +++         ++l  ++++G+l+e r+d+ v+r+l+
     EEA19214.1 272 -SGLDSAL-SGLDMDMPGAIDWVDsatnsyfGNNLTTMINNGSLSEWRLDDMVKRILT 327
                    .3344444.799999999999887888888889***********************96 PP

>> Fn3-like  Fibronectin type III-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.5   0.0   1.8e-24   1.1e-20       2      71 .]     705     782 ..     704     782 .. 0.93

  Alignments for each domain:
  == domain 1  score: 73.5 bits;  conditional E-value: 1.8e-24
                 EEEEEEEESS-.......STTSBS-EEEEEEEEE.E-TT-EEEEEEEEECGGG-EEETTTTEEE--SCEEEEEEESSS CS
    Fn3-like   2 vvqlYvsdpes.......sverpvkeLkgFekve.LapGesktvtftldrkdlsvwdeekqkwvvepGeytvlvgtss 71 
                 v q+Y+s+p++       ++++pvk+L+gF++++ L+pG s +++f+l r d+s+wd+ +q+wv+++G++ vl g ss
  EEA19214.1 705 VPQVYLSFPSAqtnisdnGLPTPVKVLRGFDRTDiLKPGHSVKLRFDLRRMDVSSWDVVRQEWVIPSGTFGVLAGWSS 782
                 99********655555558********************************************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (794 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       337  (0.0187964); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.52
# Mc/sec: 4553.66
//
Query:       EEA19215.1  [L=187]
Description: hypothetical protein PMAA_014750 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.046   13.1   0.1      0.059   12.7   0.1    1.2  1  DUF4504   Domain of unknown function (DUF4504)


Domain annotation for each model (and alignments):
>> DUF4504  Domain of unknown function (DUF4504)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.1   3.3e-06     0.059     205     246 ..     109     153 ..      92     166 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 3.3e-06
     DUF4504 205 eskkkseeLlsFsvPeelsse....ikssleqWakalqarfkkkqv 246
                 ++++++ ++ls svP+el s+    +  ++ +W+++l  rf++k v
  EEA19215.1 109 NHNRSTTTILSASVPAELPSAtyntVSPHKHKWLNKLDPRFNAK-V 153
                 5666779***********9888888999**************99.3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (187 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1245  (0.0694406); expected 358.6 (0.02)
Passed bias filter:                      538  (0.0300073); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 1293.15
//
Query:       EEA19216.1  [L=734]
Description: mycelial catalase Cat1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   2.4e-163  543.7   0.0     3e-163  543.4   0.0    1.1  1  Catalase      Catalase
    1.1e-47  161.5   1.6    1.8e-47  160.8   1.6    1.4  1  Catalase_C    C-terminal domain found in long catalases
      4e-14   52.6   0.0    7.4e-14   51.7   0.0    1.5  1  Catalase-rel  Catalase-related immune-responsive
  ------ inclusion threshold ------
        0.2   11.9   0.0         15    5.9   0.0    2.3  2  DUF3727       Protein of unknown function (DUF3727)


Domain annotation for each model (and alignments):
>> Catalase  Catalase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  543.4   0.0  6.6e-167    3e-163       2     382 ..      69     452 ..      68     453 .. 0.97

  Alignments for each domain:
  == domain 1  score: 543.4 bits;  conditional E-value: 6.6e-167
                 -TTS-B-S-SSS-EEESTTS-BBTT-HHHHHHHHHHHT------SS--SEEEEEEEEEESS--TTT---GGGSSTT-EEEEEEEEE-SS--TT--SSSS CS
    Catalase   2 tseGapvsdnqnsltagerGplllqdvhlieklahfdreripeRvvhAkGagahgeFevtkdisdltkakllskvgkktpvlvRfStvagekgsadtaR 100
                 ++ G p+ ++q+sl+ag rG +ll+d+++++k++hfd+eripeR vhA+Gagahg+F+ ++d+s++t+a++l  +gk+tp++vRfStvag++gsadtaR
  EEA19216.1  69 SDVGGPI-EDQHSLKAGIRGSTLLEDFIFRQKIQHFDHERIPERAVHARGAGAHGVFTSYADWSNITAASFLGAAGKETPTFVRFSTVAGSRGSADTAR 166
                 5667788.5799*************************************************************************************** PP

                 S--EEEEEEEETTEEEEEEEESSSS-S-S-GGGHHHHHHHHSB-TTT-SB....-HHH..HHHHHHT-GGGHHHHHHHHSGGGSBS-GGGS-EE--S-E CS
    Catalase 101 dvrGfavkfyTeeGnwDlvgnntpvFfirDpikfpdlihsqkrepqtnlk....daam..fwdflslnpeslhqvlilfsdrgipksyrhmngygvhtf 193
                 dv+Gfa++fyTeeGn+D+vgnn+pvFfi+D+i fpdlih++k++p+++++    +  +  ++df+ ++p +lh++++++s +gip+s+rh++g+gvht+
  EEA19216.1 167 DVHGFATRFYTEEGNYDIVGNNIPVFFIQDAILFPDLIHAVKPQPANEIPqaatA--HdtAYDFFGQQPSTLHTLFWAMSGHGIPRSFRHVDGFGVHTY 263
                 **************************************************65333..2669************************************** PP

                 EEE-TT--EEEEEEEEEETT---B--HHHHHHHHHH-TTHHHHHHHHHHHTT---EEEEEEEEEEHHHHTTTHHHHT-TT----TTTS--EEEEEEEEE CS
    Catalase 194 klvnkegevvyvkfhfktkqgvknltaeeaeklagedpdyatrdLyeaiekgeypewelyvqvmteeeaeklrfnilDlTkvwpekevplrevGkltLn 292
                 ++v+++g+++ vkfh+++ qg ++l++eea+++ag+++dy+++dLy++i++g+ypewel vq+++e++  ++ f++lD+Tk++p +evp++++Gk++Ln
  EEA19216.1 264 RFVTDNGSSKLVKFHWTSLQGRASLVWEEAQATAGKNADYMRQDLYDSIKAGRYPEWELGVQIINESDVLSYGFDLLDPTKILPVEEVPITPLGKMQLN 362
                 *************************************************************************************************** PP

                 E--S-HHHHTTT----TT---TTEE--S-HHHHHHHHHHHHHHHHHT.-TTGGGSGGG---..---S----TT-.....S-S---SS-S-T CS
    Catalase 293 rnpenyFaevEqvafspsnlvpGiepseDklLqgRlfsYadtqryRl.GvnyqqlpvNrpkakvanyqrdGamrveankgkepnYepnsle 382
                 rnp nyFae+Eqv+f+p+++v+Gi+++eD+lLqgRlfsY dtq +R  G+n++q+p+Nrp+++++n++rdG+ ++ +  ++ + Y pn+l+
  EEA19216.1 363 RNPLNYFAETEQVMFQPGHIVRGIDFTEDPLLQGRLFSYLDTQLNRNgGPNFEQIPINRPRVPIHNNNRDGFGQMFIPLNQ-AAYSPNTLN 452
                 ***********************************************99****************999******9888776.99***9875 PP

>> Catalase_C  C-terminal domain found in long catalases
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  160.8   1.6     4e-51   1.8e-47       1     152 []     579     731 ..     579     731 .. 0.98

  Alignments for each domain:
  == domain 1  score: 160.8 bits;  conditional E-value: 4e-51
  Catalase_C   1 dglkVgiLasndseaslaqakalaaalaaegvdvtvvaeklgsaegvnrTYstadaveFDaivvadgaeslfsak...ataasslfpagrplqlllday 96 
                 dgl+V++Las ++e s+a+ +ala++la+++vdv++vaekl  a++v++TYs +da++FDa++v++ga++lf  +   +t++ +l+pagrp q+++da+
  EEA19216.1 579 DGLRVAVLASVNDERSIAEGQALAKRLANSNVDVVIVAEKL--ASNVTATYSESDATNFDAVIVTSGADGLFGLQtftSTSNITLYPAGRPTQIMVDAF 675
                 79***************************************..*****************************877899999****************** PP

  Catalase_C  97 rhgKpigalGsgaealkaagisaeepGVyvadsasealvekvkegLatfrfldRfp 152
                 r+gKp+ga+Gs+++al+a++is+++ GV+++ds+++++v+++++ Latf+fldRf+
  EEA19216.1 676 RFGKPVGAVGSARSALSAVDISTNRTGVVIGDSVNDDFVNQLTKDLATFKFLDRFA 731
                 *******************************************************7 PP

>> Catalase-rel  Catalase-related immune-responsive
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.7   0.0   1.6e-17   7.4e-14       2      64 ..     485     547 ..     484     548 .. 0.96

  Alignments for each domain:
  == domain 1  score: 51.7 bits;  conditional E-value: 1.6e-17
                   HGG--SSHHHHHHHHHS-HHHHHHHHHHHHHHHTTSS-HHHHHHHHHHHHHH-HHHHHHHHHH CS
  Catalase-rel   2 edfddhfsQagllyrsmseeekerlvnniafelskvedeeiqerqlehfakvDpdlgqrVaea 64 
                    +f+d +sQ+gl+y+s+++ e++ ++n ++fels+v +e+++++ + + ++v+++l++ Va+a
    EEA19216.1 485 PTFADVWSQPGLFYNSLTATEQQFVINGLRFELSNVGSEDVKRNFITQVNRVNNTLATLVATA 547
                   5799*********************************************************97 PP

>> DUF3727  Protein of unknown function (DUF3727)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.0    0.0034        15       2      53 ..      13      63 ..      12      68 .. 0.78
   2 ?    3.5   0.0     0.019        85      44      67 ..     171     194 ..     154     206 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0034
     DUF3727  2 LtLkrtavtltveGeLppleeeeileleeeedeeeleeEelqllasFyheeq 53
                L+   +a +  ++GeLp  +  +  +  + +d ++  +E+  +l +Fy +++
  EEA19216.1 13 LVVAASAACPMLTGELPAGSVANPHHHGKRDD-SKASSETETFLSEFYLNDN 63
                567789999999****9777666655554555.589999999******9986 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.019
     DUF3727  44 llasFyheeqeYsiytpldPlllv 67 
                 + ++Fy ee +Y i+    P++++
  EEA19216.1 171 FATRFYTEEGNYDIVGNNIPVFFI 194
                 5678*****************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (734 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       370  (0.020637); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.46
# Mc/sec: 4820.22
//
Query:       EEA19217.1  [L=479]
Description: DUF895 domain membrane protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-09   36.7  33.0    2.2e-09   36.7  33.0    1.3  1  MFS_1     Major Facilitator Superfamily
    1.7e-05   24.6   5.2    1.7e-05   24.6   5.2    2.6  3  UNC-93    Ion channel regulatory protein UNC-93


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.7  33.0   2.5e-13   2.2e-09      22     335 ..      67     403 ..      47     423 .. 0.62

  Alignments for each domain:
  == domain 1  score: 36.7 bits;  conditional E-value: 2.5e-13
       MFS_1  22 alaedlgispseigllltl.yalga..avaslplGrlsdr.fGrrrvlllglllfalglllllfass....lwlllvlrvlqGlgagalfpagaaliad 112
                   +++lg  ++e   l+ +  al++  +v+s ++G ++ + +G +++++lg ++fa + +++l++++     wl+l++ +l+Gl ag+++ a aa++ +
  EEA19217.1  67 GAMNSLGGGGDEKPYLVNAaNALTFclMVLSCFFGTVIVKyIGIKWTFILGTVGFAPF-AAGLYTHNrygmDWLVLLGAALCGLSAGIFWMAEAAIALA 164
                 445667777777666444434443334888889988888857****************.666656445555999************************* PP

       MFS_1 113 wfpkeergraigllsagfslGailgpllggllasslg.....Wravfyilaivsllafvlfllllpeepperkrkspkeee..kgtgpaplvpawkall 204
                 +  + ++gr +g++ ++  +G ilg ++   + +  +        vf ++ ++ +la  ++lll p ++++r    p+ ++   +   a+l+++ k+++
  EEA19217.1 165 YPEPYNQGRFLGFWLSFRVAGQILGGAVNLGINAKNSqagkvSYTVFELFIALQALAPFVGLLLSPPKKVQRTDGLPVGLRifDQSWTAELKEVVKLFV 263
                 *999****************************9777789888555555555555555333224444444444444444443664444444444667777 PP

       MFS_1 205 kdpvlwillialllfffgfsglltllplylqevlgls..glllaglllallalvgailallagrlsdrlgr..rrrlllallllllaalglallavt.. 297
                 ++ +l  l++ l++ + ++s +++++       l +s  +   +g  + l+++v++i++ l+g+++d  +   ++r   +++++l +  ++ +++ t  
  EEA19217.1 264 SRDFL--LIVPLICQA-VYSEAVMFTYQ----GLWFSvrA-RALG--SFLSGIVALIGGNLLGAYLDTRKVslKTRARTSFIIVLGFQGAWWIWG-Tvl 351
                 77766..888888885.55554444433....44444433.5555..666666666668888888855444113344444333333333333333.348 PP

       MFS_1 298 ......ssavllll........vlvliGfglgfvfpsllalasdlappeeag 335
                       +++v  +         +l+l+ + ++ v+ ++l++++ ++ ++e+ 
  EEA19217.1 352 vtrynrTNPVYDWTdpgfgsgfALFLFWVIGFQVNYLYLYFVVGNLAKNEQE 403
                 8888875555555575555544333333322223555555555555555554 PP

>> UNC-93  Ion channel regulatory protein UNC-93
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.6   5.2   1.9e-09   1.7e-05      42     111 ..      86     159 ..      81     202 .. 0.87
   2 ?   -1.1   0.5      0.16   1.4e+03      63     108 ..     262     309 ..     255     356 .. 0.59
   3 ?   -3.2   1.5      0.68   6.1e+03      74      94 ..     373     392 ..     371     399 .. 0.66

  Alignments for each domain:
  == domain 1  score: 24.6 bits;  conditional E-value: 1.9e-09
      UNC-93  42 slaiiyavftvanlvapsvvdlltakwalvigallyaifqlgFlllnk....yylyissallGvgaallwtgqG 111
                 + a+++   ++++++   +v+ ++ kw+ ++g++ +a f +g    n+    +++++++al G++a ++w+++ 
  EEA19217.1  86 ANALTFCLMVLSCFFGTVIVKYIGIKWTFILGTVGFAPFAAGLYTHNRygmdWLVLLGAALCGLSAGIFWMAEA 159
                 57999***************************************99973333689***************9986 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.16
      UNC-93  63 lltakwalvigallyaifqlgFlllnk..yylyissallGvgaallwt 108
                 +++  ++l++  ++ a++  + +++++  ++   + al  + + ++  
  EEA19217.1 262 FVSRDFLLIVPLICQAVYSEAVMFTYQglWFSVRARALGSFLSGIVAL 309
                 566678888888888888766666555225555555555543333333 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 0.68
      UNC-93  74 allyaifqlgFlllnkyylyi 94 
                 ++l++++ +gF ++n  yly+
  EEA19217.1 373 FALFLFWVIGF-QVNYLYLYF 392
                 56677777776.666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (479 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       574  (0.0320152); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.48
# Mc/sec: 2970.31
//
Query:       EEA19218.1  [L=501]
Description: MFS sugar transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.3e-97  325.5  27.1    6.1e-97  325.3  27.1    1.0  1  Sugar_tr  Sugar (and other) transporter
    1.4e-23   83.4  27.8    1.4e-23   83.4  27.8    2.3  3  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  325.3  27.1  6.8e-101   6.1e-97       9     452 .]      24     470 ..      16     470 .. 0.91

  Alignments for each domain:
  == domain 1  score: 325.3 bits;  conditional E-value: 6.8e-101
                 H.HHHHHHHHCGGGTHHHHHHHHTST.T--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGG CS
    Sugar_tr   9 g.llfgYdtgvigafltllkfaknfg.lsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevl 105
                   + fgY+++v g+ lt+++f+ +f  +++ ++s++  s  +g +v+++ +G+++G+l + ++gd++GR+k++ ia++l++ig+vl+  +    s+ ++
  EEA19218.1  24 AyMCFGYNLAVAGGLLTMPSFIAHFPkMDTVHNSDKFHSNIQGTVVALYTIGGMLGALSTIFVGDILGRRKVIFIASALVIIGSVLMSSSY---SLGQF 119
                 4478******************99984444444454478899*************************************************...9**** PP

                 GGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-.TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHHTT- CS
    Sugar_tr 106 ivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsn.adgwrillglqlvpallllilllflPESPrylvekgk 203
                 iv+R++ G+g G+++++vP+++sEi+  ++Rg  v+   l++ +Gi  + +++lg+++++  ++ wr++l lq  + ++++i+++ lPESPr+l+ kg+
  EEA19218.1 120 IVARLVQGLGTGATTATVPVWQSEISGSAHRGSHVVTEGLFVCVGIAASLWIDLGFSYINTsSVAWRVPLILQTSLVIFVMIFIFQLPESPRWLLGKGR 218
                 ***********************************************************9999************************************ PP

                 HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH......HTTHHHHSH.....HHHHHHHHHHHHHHTTHHHHHHHTTTHHHH...SS-THHHHHHHHH CS
    Sugar_tr 204 eeeakevlaklrgeedadrelaeekdsleaeqeee.kaswkellsskt..vrqrlligvvlqifqqltGinaimyysptifen...lglsksllvtiiv 296
                  eea+e+l  lr++e+ d+ +  e+++ +++ e   +as   ++++ +  +  rl +g++ q+f ql+Gin++++y+++if++   +g  +s + ++++
  EEA19218.1 219 VEEAREILTILRDVEPGDETVCREIAEVQKSLELVqNASRLDIFKMGEkrNAHRLALGMAGQSFGQLCGINSLTFYATVIFNQrlhMGAINSRILSAGM 317
                 **************777777777777777775544666666666664467899****************************975334555669****** PP

                 HHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHH CS
    Sugar_tr 297 gvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavn 395
                 ++++++  f+aif++dr+GRR+l++ +a+gm+i +v+l++ + ++ +  +aa iv++v+++ f  ++ +g+ +vp+++++E++p+++R+k + i+ ++ 
  EEA19218.1 318 VTIQVIGAFFAIFTIDRWGRRPLMFASATGMCITMVVLAGTTSATGN--QAALIVSVVALYGFNLFYPFGFLGVPFLYSTEVAPPHLRAKISGISNCMT 414
                 **************************************933333333..479*********************************************** PP

                 HHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 396 wlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 wl+ f++  ++p+ +++ig +++++++a+++ + ++ v+ff+pet  r+lee++e+f
  EEA19218.1 415 WLFKFVVVEVTPTGFQTIG-YKYYIIWAVINFAIVVTVYFFFPETNARSLEEMDEIF 470
                 *******************.**********************************997 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.0   0.4     0.037   3.3e+02     223     254 ..      15      44 ..       4      50 .. 0.63
   2 !   83.4  27.8   1.6e-27   1.4e-23       4     344 ..      24     414 ..      17     421 .. 0.76
   3 ?    1.2   0.1     0.016   1.4e+02     154     179 ..     437     462 ..     427     472 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.0 bits;  conditional E-value: 0.037
       MFS_1 223 fsglltllplylqevlglsglllaglllalla 254
                  ++ll+ +p y+ + ++l+  + +gll + ++
  EEA19218.1  15 ATILLVVFPAYMCFGYNLA--VAGGLLTMPSF 44 
                 4458888888888888888..44443333333 PP

  == domain 2  score: 83.4 bits;  conditional E-value: 1.6e-27
       MFS_1   4 aaflsalarsilgpalpl.al............aedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.ll 88 
                 a+++ +++ +++g +l++               ++ ++     +g++++ly++g ++++l + +++d +Grr+v++++ +l ++g++l++ +s +   +
  EEA19218.1  24 AYMCFGYNLAVAGGLLTMpSFiahfpkmdtvhnSDKFH--SNIQGTVVALYTIGGMLGALSTIFVGDILGRRKVIFIASALVIIGSVLMS-SSYSLgQF 119
                 55555555555554444322234445555555455566..6668*****************************99999999999956666.3344458* PP

       MFS_1  89 lvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg.....Wravfyilaivsllafvlfllllpeepperkrk 182
                 +v+r++qGlg+ga ++++ ++ ++++   +rg+ +   ++++ +G++    +   ++ +++     Wr++ ++ + + +++++   + +  ++++r+  
  EEA19218.1 120 IVARLVQGLGTGATTATVPVWQSEISGSAHRGSHVVTEGLFVCVGIAASLWIDLGFS-YINtssvaWRVPLILQTSLVIFVMI---FIFQLPESPRWLL 214
                 *************************************************99999666.22234666***************99...8999999999998 PP

       MFS_1 183 spkeee.................................kgtgpaplvpawkallkdpvlw.illialllfffgfsglltllplylqevlgls....gl 243
                  + + e                                 +   +  +++  ++ ++   l   +   +++  +g+++l+++ +++++++l+++      
  EEA19218.1 215 GKGRVEeareiltilrdvepgdetvcreiaevqkslelvQNASRLDIFK-MGEKRNAHRLAlGMAGQSFGQLCGINSLTFYATVIFNQRLHMGainsRI 312
                 88888889**********9999999999996666665554444444444.5555555555357888899999999*********99*******555533 PP

       MFS_1 244 llaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavt.ssavllll.vlvliGf.glgfv..fpsllalasdlappeeagta 337
                 l+ag  +  ++++g   a++a + +dr+grr+ ++ +  ++ ++ + la +  +  ++++l++ v++l+Gf  +  +   +  + + +++app+ ++++
  EEA19218.1 313 LSAG--MVTIQVIG---AFFAIFTIDRWGRRPLMFASATGMCITMVVLAGTTSAtGNQAALIVsVVALYGFnLFYPFgfLGVPFLYSTEVAPPHLRAKI 406
                 5555..55555555...55555566*****9999999999998888888888885333333335666677765555556677778888999******** PP

       MFS_1 338 sglfn.ta 344
                 sg+ n ++
  EEA19218.1 407 SGISNcMT 414
                 ****9444 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.016
       MFS_1 154 fyilaivsllafvlfllllpeepper 179
                 ++i a++ +  +v +++++pe++ ++
  EEA19218.1 437 YIIWAVINFAIVVTVYFFFPETNARS 462
                 88999999999999899999887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (501 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       823  (0.0459033); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3384.13
//
Query:       EEA19219.1  [L=482]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.2e-05   22.4   0.1      0.013   14.2   0.0    3.0  3  Transferase  Transferase family


Domain annotation for each model (and alignments):
>> Transferase  Transferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.0     0.014   2.6e+02      25      77 ..       9      59 ..       3      68 .. 0.69
   2 !   14.2   0.0   7.1e-07     0.013     130     184 ..     134     186 ..     124     393 .. 0.84
   3 !    4.3   0.0   0.00074        13     382     433 ..     418     472 ..     417     473 .. 0.78

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 0.014
  Transferase 25 SilDlllpevivkacyfykknkelsqenvsekLktsLsetL..tkfypLAGrLkt 77
                   lD  +    ++ c+  k  ++l++    + L +sL++++  +++  + GrL++
   EEA19219.1  9 YYLDSTYQARSTVMCLTLKFDDVLNA----DMLHESLVKLIknDHWRKIGGRLRR 59
                 55565555555555555555555555....57********955589999999966 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 7.1e-07
  Transferase 130 aipllavqvTkfkcGgvalgvsvsHaiaDgaSlktfieswaelargekkvtvtpl 184
                    p l + +  f +G   ++ +  H++ D+ +  ++ ++w ++  g+ + +  p+
   EEA19219.1 134 YLPQLYLHIVTFTDG-TLVSLTWPHTMSDISGWGHIFRAWSAVLSGK-PYNAIPQ 186
                  4788999999*****.99***************************99.5555554 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.00074
  Transferase 382 GwgkPvyvvpvvsskkdnk...illlpskeddggvevlvtLpeeemskfeeeael 433
                  G g+P y  + v sk +     ++ l +++ +g   v ++L++++m+ fe+++e+
   EEA19219.1 418 GVGRPSYFHSDVLSKSALHdkdVFNLYGRDSEGNYWVGAVLSKKAMKNFEKKFEA 472
                  567777777777665443333488899999999999****************995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (482 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       375  (0.0209158); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.29s 00:00:00.85 Elapsed: 00:00:00.46
# Mc/sec: 3118.90
//
Query:       EEA19220.1  [L=241]
Description: hypothetical protein PMAA_014800 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    0.00016   22.1  10.3      0.006   17.0  10.3    2.3  1  ZapB          Cell division protein ZapB
    0.00023   20.6   6.6    0.00035   20.0   6.6    1.3  1  GAS           Growth-arrest specific micro-tubule binding
    0.00082   18.8   0.6     0.0014   18.0   0.6    1.3  1  DUF3450       Protein of unknown function (DUF3450)
     0.0071   15.7   2.2       0.01   15.1   2.2    1.2  1  HemX          HemX, putative uroporphyrinogen-III C-methyltra
  ------ inclusion threshold ------
      0.012   15.4   6.5      0.019   14.8   6.5    1.2  1  KASH_CCD      Coiled-coil region of CCDC155 or KASH
      0.014   15.6   4.6      0.026   14.7   4.6    1.4  1  TMF_TATA_bd   TATA element modulatory factor 1 TATA binding
      0.014   15.1   6.5       0.36   10.6   1.4    2.3  2  DivIC         Septum formation initiator
      0.014   14.3   3.3      0.028   13.3   3.3    1.4  1  Spc7          Spc7 kinetochore protein
      0.016   15.5   2.6       0.06   13.7   2.8    1.8  1  BLOC1_2       Biogenesis of lysosome-related organelles compl
      0.024   14.6   1.5      0.046   13.7   1.5    1.4  1  Laminin_II    Laminin Domain II
      0.081   13.0   1.2       0.18   11.8   1.2    1.6  1  Rubredoxin    Rubredoxin
        0.1   12.6   0.4       0.18   11.8   0.4    1.3  1  DUF1664       Protein of unknown function (DUF1664)
       0.12   12.5   7.9        1.3    9.2   2.3    2.5  2  bZIP_1        bZIP transcription factor
       0.16   12.5   8.9       0.26   11.8   8.9    1.4  1  APG6_N        Apg6 coiled-coil region
       0.17   12.1  15.9      0.044   14.0  12.9    1.4  2  ATG16         Autophagy protein 16 (ATG16)
       0.18   11.6   5.0       0.85    9.4   3.2    2.2  2  Phage_GP20    Phage minor structural protein GP20
       0.22   12.2   1.8       0.49   11.2   1.8    1.6  1  Occludin_ELL  Occludin homology domain
       0.32   11.2  10.0       0.45   10.8   2.6    2.4  2  HALZ          Homeobox associated leucine zipper
       0.36   10.8   8.8        1.2    9.2   8.5    2.0  2  TMF_DNA_bd    TATA element modulatory factor 1 DNA binding
        0.5   10.6   5.9        1.5    9.1   5.6    2.0  2  Cnn_1N        Centrosomin N-terminal motif 1
       0.55   10.4   8.6        1.6    8.8   3.1    2.4  2  bZIP_2        Basic region leucine zipper
       0.69    9.8   3.8        1.2    9.0   0.3    2.5  2  GIT_CC        GIT coiled-coil Rho guanine nucleotide exchange
        0.8   10.3   6.0         14    6.3   2.3    2.5  2  Syntaxin-6_N  Syntaxin 6, N-terminal
        2.2    8.7   8.6       0.13   12.7   2.6    2.0  2  CENP-H        Centromere protein H (CENP-H)
        3.6    6.6  11.7       0.12   11.4   5.0    1.8  2  Atg14         Vacuolar sorting 38 and autophagy-related subun
        4.1    7.6   6.0        2.5    8.2   1.2    2.1  2  DUF5595       Domain of unknown function (DUF5595)
        4.7    7.2   6.1        4.4    7.3   0.5    2.4  2  WD40_alt      Alternative WD40 repeat motif


Domain annotation for each model (and alignments):
>> ZapB  Cell division protein ZapB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0  10.3     9e-06     0.006      15      64 ..     163     226 ..     152     229 .. 0.66

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 9e-06
        ZapB  15 kaidtitlLqmeieeLkeeneelkeenrele..............eeneqlkeereawqerlkk 64 
                 + +d + lL+ +++eL ee+++lke+++  e              +++e+lk+er  ++e+l+k
  EEA19220.1 163 THLDHLHLLRTRNAELTEEVKALKERANSGEetswelkeynenleAQVEELKAERDGLHEKLRK 226
                 5555566666666666666655555555555555555544444449999999999999999998 PP

>> GAS  Growth-arrest specific micro-tubule binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   6.6   5.3e-07   0.00035      53     131 ..     148     226 ..     119     230 .. 0.91

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 5.3e-07
         GAS  53 sqenkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkelekelkdlkwehevleqrfekvekerdelykkfea 131
                 s++  +l+  L++ +  +++L+    +  +  ++ k+lk+r ++ e+   +lk+ +e+le ++e++++erd l++k ++
  EEA19220.1 148 SSQPDELQTALHTIQTHLDHLHLLRTRNAELTEEVKALKERANSGEETSWELKEYNENLEAQVEELKAERDGLHEKLRK 226
                 6677899********************************************************************9886 PP

>> DUF3450  Protein of unknown function (DUF3450)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.6   2.1e-06    0.0014      10      94 ..     146     230 ..     140     235 .. 0.90

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 2.1e-06
     DUF3450  10 asgalaatldqalkeaekavaaaaqsqkkidklddekqellaeyralkeeleslevyneqlerlvasqeqeiasleeqieeieei 94 
                 +s++  ++l++al++ +   +      ++  +l++e + l+++ ++ +e   +l+ yne+le++v+++++e++ l e++ +i+++
  EEA19220.1 146 SSSSQPDELQTALHTIQTHLDHLHLLRTRNAELTEEVKALKERANSGEETSWELKEYNENLEAQVEELKAERDGLHEKLRKIRRL 230
                 455567888888999999999999999999**************************************************99875 PP

>> HemX  HemX, putative uroporphyrinogen-III C-methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   2.2   1.6e-05      0.01      29     103 ..     144     217 ..     134     230 .. 0.91

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 1.6e-05
        HemX  29 qvqeltaevaelqqqlaaleqqlaqveaekeqkqeleerlqqlaeklealekeleqlqkqleelqqqlskvsgae 103
                 q+ + +++ +elq++l+++++ l++++ ++++++el+e++++l+e+ ++ e+++ +l++  e+l++q++++++++
  EEA19220.1 144 QF-SSSSQPDELQTALHTIQTHLDHLHLLRTRNAELTEEVKALKERANSGEETSWELKEYNENLEAQVEELKAER 217
                 44.566777*************************************************************99874 PP

>> KASH_CCD  Coiled-coil region of CCDC155 or KASH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.8   6.5   2.9e-05     0.019      47     111 ..     153     217 ..     148     231 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 2.9e-05
    KASH_CCD  47 eLkkklkstQqalqkaklleeEleelkalvkeleEkrarlkaqnkqlekenqsLiakiesLqeen 111
                 eL++ l+  Q  l + +ll   ++el + vk l+E++++ +  +++l+  n+ L+a++e+L+ e 
  EEA19220.1 153 ELQTALHTIQTHLDHLHLLRTRNAELTEEVKALKERANSGEETSWELKEYNENLEAQVEELKAER 217
                 89999999999999*********************************9999****9999998775 PP

>> TMF_TATA_bd  TATA element modulatory factor 1 TATA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   4.6   3.9e-05     0.026      40     106 ..     149     215 ..     144     222 .. 0.94

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 3.9e-05
  TMF_TATA_bd  40 aerdeareeivklmkeneelkelkkeleelekeleelqeryetlLellGeksEeveELraDvaDlKe 106
                  ++ de++  + ++ +  + l+ l ++++el++e+++l+er ++  e   e +E +e L+a v++lK+
   EEA19220.1 149 SQPDELQTALHTIQTHLDHLHLLRTRNAELTEEVKALKERANSGEETSWELKEYNENLEAQVEELKA 215
                  677899999999999***************************************************6 PP

>> DivIC  Septum formation initiator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   0.3    0.0063       4.2      31      51 ..     166     186 ..     153     191 .. 0.79
   2 ?   10.6   1.4   0.00054      0.36      15      50 ..     192     227 ..     188     233 .. 0.84

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0063
                 HHHHHHHHHHHHHHHHHCC-X CS
       DivIC  31 aelaklkaeneeLeaevkdLk 51 
                 ++l  l+ +n+eL++evk Lk
  EEA19220.1 166 DHLHLLRTRNAELTEEVKALK 186
                 55666899**********996 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00054
                 XXXHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC- CS
       DivIC  15 gllaykqlkqeiaalqaelaklkaeneeLeaevkdL 50 
                 g  + ++lk+  + l+a++++lkae++ L +++++ 
  EEA19220.1 192 GEETSWELKEYNENLEAQVEELKAERDGLHEKLRKI 227
                 556789999999999999999999999999888775 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   3.3   4.3e-05     0.028     169     233 ..     168     231 ..     142     239 .. 0.63

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 4.3e-05
        Spc7 169 lpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleele 233
                 l+ l+++ ael+ee++ l+e+a++ e  ++ eL+e+ e+l+++ +e+++ ++ l e+ +++ +l+
  EEA19220.1 168 LHLLRTRNAELTEEVKALKERANSGE-ETSWELKEYNENLEAQVEELKAERDGLHEKLRKIRRLS 231
                 34456777777777777777777644.46777777777777777777777777777766666654 PP

>> BLOC1_2  Biogenesis of lysosome-related organelles complex-1 subunit 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   2.8     9e-05      0.06      14      68 ..     160     214 ..     154     227 .. 0.91

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 9e-05
     BLOC1_2  14 eleatvedyklLeklNeaasekykklkdvaaslekkleklnekyeelqpylqqid 68 
                 +++   +++ lL + N + +e++k+lk++a+s e+++ +l+e +e+l+ ++++++
  EEA19220.1 160 TIQTHLDHLHLLRTRNAELTEEVKALKERANSGEETSWELKEYNENLEAQVEELK 214
                 67778899****************************************9999886 PP

>> Laminin_II  Laminin Domain II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   1.5   6.9e-05     0.046      26      98 ..     161     230 ..     147     234 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 6.9e-05
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--TTTTTGGGHHHHHHHHHH...HHHHHHHHHHH CS
  Laminin_II  26 lentkeklseinrsveetnekvkdankairdArrsvkkLeklapqLldklkelkqleeassslsdniseikel 98 
                 ++   + l+ +++  +e +e+vk++++  ++ ++ + +L++  ++L+++++elk  +++   l +++ +i+ l
  EEA19220.1 161 IQTHLDHLHLLRTRNAELTEEVKALKERANSGEETSWELKEYNENLEAQVEELKAERDG---LHEKLRKIRRL 230
                 4455567888899999*******************************************...99******987 PP

>> Rubredoxin  Rubredoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   1.2   0.00028      0.18      32      43 ..      23      34 ..      20      37 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00028
                -TT-BBTTTB-B CS
  Rubredoxin 32 PddWvCPdCgve 43
                P dW+CPdC+ +
  EEA19220.1 23 PTDWQCPDCKTG 34
                99*******975 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.4   0.00027      0.18      39     112 ..     154     226 ..     150     233 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00027
     DUF1664  39 lsdavesvskqleqvseslaatkrhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeaveg 112
                 l+ a++++ ++l+++   l++   +L+++++ + ++ ++ +e+s e+ke  ++++ +++e++ + + ++e  ++
  EEA19220.1 154 LQTALHTIQTHLDHLH-LLRTRNAELTEEVKALKERANSGEETSWELKEYNENLEAQVEELKAERDGLHEKLRK 226
                 8899999999**9986.577777888888888888888888888888777777777777777777777766554 PP

>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   1.4    0.0067       4.4      31      63 ..     171     203 ..     165     204 .. 0.87
   2 ?    9.2   2.3    0.0019       1.3      25      52 ..     200     227 ..     198     231 .. 0.90

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0067
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  31 LerrvkaLekeNksLkseleelkkevekLkskv 63 
                 L +r ++L++e k+Lk+++++ ++++ +Lk+ +
  EEA19220.1 171 LRTRNAELTEEVKALKERANSGEETSWELKEYN 203
                 788999999999999999999999999999765 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.0019
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  25 qaeieeLerrvkaLekeNksLkseleel 52 
                 +++ e+Le +v++L++e   L ++l ++
  EEA19220.1 200 KEYNENLEAQVEELKAERDGLHEKLRKI 227
                 7999******************999876 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   8.9   0.00039      0.26      25     126 ..     151     224 ..     105     231 .. 0.59

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00039
      APG6_N  25 rdaYeeflkklkkekkeeekqdeeleeleeeleklekeeeelleeLkelekereeleaelaaleeelealeeeeerfwreynelqlelleleeeldsle 123
                  d++++ l++++++ ++    ++  +el ee+++l++  ++ +e   el++ +e+lea++++l++e + l+e+                          
  EEA19220.1 151 PDELQTALHTIQTHLDHLHLLRTRNAELTEEVKALKERANSGEETSWELKEYNENLEAQVEELKAERDGLHEK-------------------------- 223
                 3444444444444444433345555555555555555555555555555555555555555555555555544.......................... PP

      APG6_N 124 aqy 126
                   +
  EEA19220.1 224 --L 224
                 ..3 PP

>> ATG16  Autophagy protein 16 (ATG16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       9.3   6.2e+03      65      65 ..      66      66 ..      36      89 .. 0.46
   2 ?   14.0  12.9   6.6e-05     0.044      44     152 ..     109     230 ..      99     234 .. 0.77

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 9.3
       ATG16 65 a 65
                +
  EEA19220.1 66 P 66
                1 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 6.6e-05
       ATG16  44 aaasakssksskksakekeasasq.............snskqsakiqsleqklaqlreelaelyksrgelaqrllelneelqkleeklkedeerlaele 129
                 +++sa+++k++kks+k ++a++++             s+s+q +++q+   +++++ + l  l  +++el++ +++l+e     ee++ e +e  ++le
  EEA19220.1 109 KSESASPTKRPKKSSKASKAQKQDcaiktdqpggmqfSSSSQPDELQTALHTIQTHLDHLHLLRTRNAELTEEVKALKERANSGEETSWELKEYNENLE 207
                 223333344444444444444444666677899988888888888888888888888888888889999999*************************** PP

       ATG16 130 aeraaletklkdreeelrekekl 152
                 a++++l+ +++ + e+lr  ++l
  EEA19220.1 208 AQVEELKAERDGLHEKLRKIRRL 230
                 *********99999999998887 PP

>> Phage_GP20  Phage minor structural protein GP20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.9    0.0013      0.87      25      70 ..     149     194 ..     144     201 .. 0.89
   2 ?    9.4   3.2    0.0013      0.85      18      66 ..     173     218 ..     164     230 .. 0.88

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0013
  Phage_GP20  25 eerdtlkeqlkdrdkqLedLkkkakdneeLqkqieelqaknkkaka 70 
                 ++ d+l++ l + ++ L+ L      n+eL+++++ l++ ++  ++
  EEA19220.1 149 SQPDELQTALHTIQTHLDHLHLLRTRNAELTEEVKALKERANSGEE 194
                 6789**********************************99887655 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.0013
  Phage_GP20  18 akldeveeerdtlkeqlkdrdkqLedLkkkakdneeLqkqieelqaknk 66 
                 ++ +e++ee++ lke+ +  +++  +Lk+    ne+L++q+eel+a+ +
  EEA19220.1 173 TRNAELTEEVKALKERANSGEETSWELKEY---NENLEAQVEELKAERD 218
                 5778999********************999...9**********99876 PP

>> Occludin_ELL  Occludin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   1.8   0.00073      0.49      33      95 ..     170     230 ..     149     232 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00073
  Occludin_ELL  33 evskkfseLerelkelkegskeykkieeeilqeykklkkdpeyqekkkrceyLkekLshiKkl 95 
                    ++ + +eL +e+k+lke+ +  +++  e l+ey++   +++  e k++ + L+ekL+ i++l
    EEA19220.1 170 LLRTRNAELTEEVKALKERANSGEETSWE-LKEYNEN-LEAQVEELKAERDGLHEKLRKIRRL 230
                   34455566779999999999988888888.8888887.68899999**************985 PP

>> HALZ  Homeobox associated leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.9     0.057        38      23      41 ..     170     188 ..     162     190 .. 0.84
   2 ?   10.8   2.6   0.00067      0.45      10      38 ..     199     227 ..     198     231 .. 0.75

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.057
        HALZ  23 sLkkenekLkaelqeLkek 41 
                  L+  n +L  e++ Lke+
  EEA19220.1 170 LLRTRNAELTEEVKALKER 188
                 688999***********97 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00067
        HALZ  10 LKasYdaLksdydsLkkenekLkaelqeL 38 
                 LK   ++L ++++ Lk+e++ L+ +l++ 
  EEA19220.1 199 LKEYNENLEAQVEELKAERDGLHEKLRKI 227
                 67777888888888888888888888775 PP

>> TMF_DNA_bd  TATA element modulatory factor 1 DNA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   1.8    0.0047       3.1      20      61 ..     153     194 ..     152     201 .. 0.82
   2 ?    9.2   8.5    0.0018       1.2      15      65 ..     176     226 ..     169     231 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0047
  TMF_DNA_bd  20 EGekLskkelklnntikkLrkknkelekeikelkkkleklek 61 
                 E++   ++ + +   +  Lr  n+el++e+k lk++ ++ e+
  EEA19220.1 153 ELQTALHTIQTHLDHLHLLRTRNAELTEEVKALKERANSGEE 194
                 666667788888888999****************99988776 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.0018
  TMF_DNA_bd  15 aqLmeEGekLskkelklnntikkLrkknkelekeikelkkkleklekelee 65 
                 a+L eE ++L+   +  ++t  +L++ n++le +++elk + + l ++l +
  EEA19220.1 176 AELTEEVKALKERANSGEETSWELKEYNENLEAQVEELKAERDGLHEKLRK 226
                 799999999999999999999999999999999999999887777777655 PP

>> Cnn_1N  Centrosomin N-terminal motif 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.2      0.19   1.3e+02      32      64 ..     160     187 ..     150     193 .. 0.51
   2 ?    9.1   5.6    0.0022       1.5      20      69 ..     179     227 ..     160     230 .. 0.77

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.19
      Cnn_1N  32 klse..eqkeellkenielkveveslqkelkekkk 64 
                  +++  ++          l++++++l+ e+k++k+
  EEA19220.1 160 TIQThlDHLHL-------LRTRNAELTEEVKALKE 187
                 44444344444.......45555555555555554 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.0022
      Cnn_1N  20 KLriyfLeerleklseeqkeellkenielkveveslqkelkekkkllrea 69 
                   +++ L+er + ++e ++ el + n +l+ +ve+l+ e + ++++lr+ 
  EEA19220.1 179 TEEVKALKERANSGEE-TSWELKEYNENLEAQVEELKAERDGLHEKLRKI 227
                 4455666676666665.999999999999999999999999999999985 PP

>> bZIP_2  Basic region leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.5      0.04        27      37      52 ..     171     186 ..     166     188 .. 0.80
   2 ?    8.8   3.1    0.0024       1.6      24      54 .]     186     216 ..     186     216 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.04
                 HHHHHHHHHHHHHHHH CS
      bZIP_2  37 LeeeNaqLrqkveqLe 52 
                 L+++Na+L ++v++L+
  EEA19220.1 171 LRTRNAELTEEVKALK 186
                 8889999999999987 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0024
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_2  24 kakeeeleervkeLeeeNaqLrqkveqLeke 54 
                 k++ ++ ee+  eL+e N+ L+++ve+L++e
  EEA19220.1 186 KERANSGEETSWELKEYNENLEAQVEELKAE 216
                 677888899999*****************98 PP

>> GIT_CC  GIT coiled-coil Rho guanine nucleotide exchange factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.2      0.86   5.7e+02      41      56 ..     153     168 ..     148     181 .. 0.68
   2 ?    9.0   0.3    0.0018       1.2      17      49 ..     195     227 ..     193     230 .. 0.90

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.86
      GIT_CC  41 slsdelrlLQskvqkL 56 
                 +l++ l+ +Q  ++ L
  EEA19220.1 153 ELQTALHTIQTHLDHL 168
                 4666777777666655 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.0018
      GIT_CC  17 eylelKkalaaseakiqqLlkvNtslsdelrlL 49 
                  ++elK+   + ea++++L++    l ++lr++
  EEA19220.1 195 TSWELKEYNENLEAQVEELKAERDGLHEKLRKI 227
                 58*******************999999999975 PP

>> Syntaxin-6_N  Syntaxin 6, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.1      0.05        33      35      60 ..     143     168 ..     120     173 .. 0.78
   2 ?    6.3   2.3     0.021        14      18      63 ..     176     223 ..     169     233 .. 0.72

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.05
  Syntaxin-6_N  35 tseeldetrteLrkalrsiewdledL 60 
                    + +++++ +eL++al++i++ l+ L
    EEA19220.1 143 MQFSSSSQPDELQTALHTIQTHLDHL 168
                   4566788899*************988 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.021
  Syntaxin-6_N  18 eslyrrwerlledtss..stseeldetrteLrkalrsiewdledLeet 63 
                   ++l ++ + l+e ++s  +ts+el+e +++L++++++++ + + L e 
    EEA19220.1 176 AELTEEVKALKERANSgeETSWELKEYNENLEAQVEELKAERDGLHEK 223
                   556666666666666654588899999999999988888887777765 PP

>> CENP-H  Centromere protein H (CENP-H)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.4       5.3   3.5e+03      61      72 ..     114     129 ..     100     138 .. 0.41
   2 ?   12.7   2.6   0.00019      0.13       6      78 ..     166     216 ..     145     235 .. 0.49

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 5.3
      CENP-H  61 k....eklkeelekle 72 
                 +    +k++++ +k++
  EEA19220.1 114 SptkrPKKSSKASKAQ 129
                 2333322222222222 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 0.00019
      CENP-H   6 eqrdelssellklsqelrelqeeltevekenlrlkrknrelaaellelakekesek..........eklkeelekleaelkks 78 
                 ++                               l+++n+el++e+  l++ ++s +          e     le+  +elk++
  EEA19220.1 166 DHLH----------------------------LLRTRNAELTEEVKALKERANSGEetswelkeynE----NLEAQVEELKAE 216
                 2333............................34566666666665555555555545555533331....222222222222 PP

>> Atg14  Vacuolar sorting 38 and autophagy-related subunit 14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.8       1.1   7.6e+02     112     142 ..     106     136 ..      56     161 .. 0.61
   2 ?   11.4   5.0   0.00018      0.12      22      87 ..     166     228 ..     132     231 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 1.1
       Atg14 112 kkRrsdleslqneleerrkkqiaklqdaikr 142
                 +k++s+ +s +++ +++ k++ a+ qd  ++
  EEA19220.1 106 SKKKSESASPTKRPKKSSKASKAQKQDCAIK 136
                 3444444444444444444444444443333 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00018
       Atg14  22 erlyelrerlaklksekeslkkkiekalegkeeaeqledkiknkkakleelksliadlrerlqelk 87 
                 ++l  lr+r+a l +e ++lk++ +  +e+ +   +l++  +n+ a++eelk+++  l+e+l++++
  EEA19220.1 166 DHLHLLRTRNAELTEEVKALKERANSGEETSW---ELKEYNENLEAQVEELKAERDGLHEKLRKIR 228
                 67888999************************...9999999999****************99997 PP

>> DUF5595  Domain of unknown function (DUF5595)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.3      0.48   3.2e+02      49      71 ..     164     186 ..     151     188 .. 0.63
   2 ?    8.2   1.2    0.0038       2.5      36      70 ..     193     227 ..     190     229 .. 0.89

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.48
     DUF5595  49 deaqlesleeeekrLeeEierle 71 
                 +  +l  l   +  L+eE+++l+
  EEA19220.1 164 HLDHLHLLRTRNAELTEEVKALK 186
                 33445556778888999999886 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.0038
     DUF5595  36 aeleskLkelynvdeaqlesleeeekrLeeEierl 70 
                 +e + +Lke ++  eaq+e+l++e+  L+e ++++
  EEA19220.1 193 EETSWELKEYNENLEAQVEELKAERDGLHEKLRKI 227
                 677889***********************998876 PP

>> WD40_alt  Alternative WD40 repeat motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   0.5    0.0066       4.4      16      31 ..     171     186 ..     167     188 .. 0.92
   2 ?    2.1   0.8      0.27   1.8e+02      14      34 ..     204     228 ..     201     230 .. 0.70

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0066
    WD40_alt  16 lkvrvseLeeEVrtLr 31 
                 l+ r +eL eEV++L+
  EEA19220.1 171 LRTRNAELTEEVKALK 186
                 79999*********98 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.27
    WD40_alt  14 eqlkvrvseLeeE....VrtLrKIn 34 
                 e+l  +v eL+ E     + LrKI 
  EEA19220.1 204 ENLEAQVEELKAErdglHEKLRKIR 228
                 8999999999999333224677775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (241 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2081  (0.116069); expected 358.6 (0.02)
Passed bias filter:                      855  (0.0476881); expected 358.6 (0.02)
Passed Vit filter:                       165  (0.00920297); expected 17.9 (0.001)
Passed Fwd filter:                        33  (0.00184059); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              27  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.46
# Mc/sec: 1589.43
//
Query:       EEA19221.1  [L=352]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
        1.8    8.9  11.6        1.2    9.5   0.3    2.8  3  MnhB             Domain related to MnhB subunit of Na+/H+ ant


Domain annotation for each model (and alignments):
>> MnhB  Domain related to MnhB subunit of Na+/H+ antiporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   2.1    0.0016        29      37     119 ..      22     111 ..      18     116 .. 0.68
   2 ?   -0.7   0.1     0.097   1.7e+03      65      83 ..     143     161 ..     116     200 .. 0.51
   3 ?    9.5   0.3   6.5e-05       1.2      30      91 ..     220     281 ..     216     293 .. 0.70

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0016
        MnhB  37 ilaaalillylafgleelekllrvklaprileglglllavltgllglllg.fltslflelel......llgeve.lgtallfdlgVylvVv 119
                 ++a+a ++ +  f ++++++ ++++++   +  ++ + ++++++l +++  fl+   + +++      ll++ + +  +++ +++++ +V+
  EEA19221.1  22 TIAIATVFTAARFAVRWTQQQREFQIE-DGISIFSWISFLVMAILYIVVTpFLYRVDIAVSTgqlyadLLKDSLfVIEIFFANTIIFWIVL 111
                 578888999999999998777777777.667777777777777777777789998888775567444433444434445555666666665 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.097
        MnhB  65 rileglglllavltgllgl 83 
                 +il+ +g ++  lt + ++
  EEA19221.1 143 TILMFIGCVISNLTSCSSM 161
                 2333333333333333333 PP

  == domain 3  score: 9.5 bits;  conditional E-value: 6.5e-05
        MnhB  30 GGFqgGlilaaalillylafgleelekllrvklaprileglgll...lavltgllglllgfltsl 91 
                 G F  G++  +  i+++++ g+e +++ ++++ +  +l+ +gl+   +av++g+l+ ++ f++s+
  EEA19221.1 220 GVFCVGVVCVIMAIIRAVSVGIESRSENTPSS-S--WLMLWGLIeaaIAVVVGTLPAFAIFFRSQ 281
                 66999*******************55555544.3..66666665111566666666555466554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (352 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       917  (0.0511462); expected 358.6 (0.02)
Passed bias filter:                      303  (0.0169); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 2373.14
//
Query:       EEA19222.1  [L=493]
Description: FAD binding domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.1e-20   71.2   0.3    1.4e-19   70.2   0.3    1.5  1  FAD_binding_4  FAD binding domain
     0.0011   19.0   1.5     0.0017   18.4   0.2    2.1  2  BBE            Berberine and berberine like


Domain annotation for each model (and alignments):
>> FAD_binding_4  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.2   0.3   1.6e-23   1.4e-19       1     138 [.      57     192 ..      57     193 .. 0.96

  Alignments for each domain:
  == domain 1  score: 70.2 bits;  conditional E-value: 1.6e-23
                    EEEEEEESSHHHHHHHHHHHHHCTSCEEEESSSTTEE.STTCSCCEEEEEETTS--EEEEETTTTEEEEETTSBHHHHHHHHHHHTTECSSGGGTT CS
  FAD_binding_4   1 paavvrpeseeevaaalrlaneaglpvlvrGgGssll.gqavatggvvldlsrlnrileideeegtatveaGvtlgdlvealaakglllglepgsg 95 
                    p+ +++++++ +v++a+ la+  + p+ v +gG+    g++  +gg+ +dl +l++ +++++++ +a ++aG ++ d++ +l+++gl +    g +
     EEA19222.1  57 PQSIFKAANAIDVSSAVLLAELFSCPFAVKSGGHAAFsGASSIQGGLNIDLGALDS-ITLNKDHTIASAGAGNVWVDVYDYLEPYGLSVI--GGRV 149
                    6789999****************************99788878********99***.8******************************99..9*** PP

                    CGSBHHHTTTTT-EETTEEGG--HHGTEEEEEEEETTSEEEEE CS
  FAD_binding_4  96 ipgtvGGaiatnagGygsekyGlirdnvlglevvladGevvrl 138
                    ++ ++GG++ +++++  s+ yG  +dnv+++e+vla G ++++
     EEA19222.1 150 STIGLGGLTTGGGISFFSQEYGWACDNVVNYELVLASGIIINV 192
                    **************************************99876 PP

>> BBE  Berberine and berberine like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   0.1       1.9   1.7e+04      13      20 ..      42      49 ..      38      51 .. 0.74
   2 !   18.4   0.2   1.9e-07    0.0017       2      41 ..     437     474 ..     436     477 .. 0.85

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 1.9
                HHHHHHHG CS
         BBE 13 ewgerYFg 20
                +w+e++++
  EEA19222.1 42 NWTESFWS 49
                78888886 PP

  == domain 2  score: 18.4 bits;  conditional E-value: 1.9e-07
                 -TTS--GGG-HHHHHHHHG.GGHHHHHHHHHHH-TT--S-- CS
         BBE   2 YvNyrdldlgkewgerYFg.gNferLvkvKtkyDPdNvFrn 41 
                 Y+Ny+ +  +   +   +g  Nf+rL  v +kyDP  vF+ 
  EEA19222.1 437 YMNYASQYQA---VIPSYGtTNFNRLKSVSAKYDPFQVFQK 474
                 7888888777...77778989******************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (493 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       414  (0.0230911); expected 358.6 (0.02)
Passed bias filter:                      294  (0.016398); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.31s 00:00:00.86 Elapsed: 00:00:00.51
# Mc/sec: 2918.83
//
Query:       EEA19223.1  [L=500]
Description: benzoate 4-monooxygenase cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.6e-56  190.9   0.0    4.2e-56  190.6   0.0    1.0  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  190.6   0.0   2.4e-60   4.2e-56      14     455 ..      53     481 ..      35     488 .. 0.82

  Alignments for each domain:
  == domain 1  score: 190.6 bits;  conditional E-value: 2.4e-60
                 HHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHHHHHHHHHTSH.ST CS
        p450  14 lqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkklRrfltptltsf.gk 111
                 l   +++++  +++kl+ kygpi r+ + +     +++p+++  ++ ++g    +r++++ ++   ++    + + + +++ + +Rr  +  ++s+  +
  EEA19223.1  53 L---QQGQFTAHIQKLHDKYGPIIRITPTE---LHVNDPDFFDILYARDG----RRHKYSYFSG--RFGYASDTFSTWQHELHHQRRKAISPFFSDrSI 139
                 2...36789999************998765...45799****99999997....7778888876..233333444444455555555555555555488 PP

                 TTHHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCCCHHHTCCSCHHHHHHH CS
        p450 112 lsleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelssllskssvqllllfpllkylptkllrklk 210
                 +++e ++   +++l++kl + ++    + + +     ++dvi++ +F +++d l++++++e ++     +  + ++   +  +fp+l+ lp++l  k++
  EEA19223.1 140 KEFELVIRAKVDKLCTKLSSYVDDGRIVHLNRAWMALTTDVITEYAFARSYDQLDSPDFQETLHDALVAIYTTGHFALHFPIVFPILDALPDWLVSKME 238
                 8************************9999999999***********************887765555444566688889999***99999998888887 PP

                 HHH...HHHHHHHHHHHHHHHHCHCHC.SCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHH CS
        p450 211 eav...kklkdlldklieerretldsa.kksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklreEide 305
                         l++ l +++ e r  l+++ ++++   + + ll++ +  +e + s++ l +++  + +aG  Tts++l+ a ++++ nP+v + lr E+ +
  EEA19223.1 239 PRLlpvLGLSKDLGQKVGEIRTGLNNQhQDTKHATIFHELLNS-NLPEE-EKSNARLGHEAQLIVAAGLITTSWALAVASFHIISNPDVSRNLRRELTS 335
                 5430113344445555666666666664444444444444443.45554.88*********************************************** PP

                 HCCTTTT-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS.CEEETTEEE-TT-EEEEEHHHHHT-TTTSSSTTS--GGGGB-TTSCTESSCTT-- CS
        p450 306 vlgdkreptyddlqklpyldavikEtLRlhpvvplllpRevtk.dvvirgylipkGtevivnlyalhrdpevfpnPeeFdpeRFldekgnskrksfafl 403
                 +  ++++ ++ dl++lpyl  +++E  Rl + v ++ pR ++  d++ ++ +ip +t v++    ++++++++p+Pe+F peR+ +++g     +++f+
  EEA19223.1 336 ANFSVENADWHDLERLPYLHGCVREGIRLAHGVTTRNPRLTPDnDLKYDDWVIPRNTPVSMTNVDILMNKDIYPDPEKFTPERWINNQG----LDHYFV 430
                 **999************************************988*******************************************98....589*** PP

                 TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGEEESSCSSEEE CS
        p450 404 PFGaGpRnCiGerlArmelklflatlLqnFevelqpetdpppileksglllp 455
                 PFG G R+C+G +lA+ el  ++at++ +Fe+el ++td  + + k++ l+p
  EEA19223.1 431 PFGRGSRMCLGVNLAQAELYHAIATIFTRFEFEL-HDTDLSDVQMKHAYLVP 481
                 *********************************9.99999999888755555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (500 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       498  (0.0277762); expected 358.6 (0.02)
Passed bias filter:                      467  (0.0260472); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.30s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 3405.64
//
Query:       EEA19224.1  [L=347]
Description: hypothetical protein PMAA_014840 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (347 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       349  (0.0194657); expected 358.6 (0.02)
Passed bias filter:                      263  (0.014669); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.47u 0.23s 00:00:00.70 Elapsed: 00:00:00.41
# Mc/sec: 2536.79
//
Query:       EEA19225.1  [L=340]
Description: hypothetical protein PMAA_014850 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (340 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       340  (0.0189637); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.31s 00:00:00.80 Elapsed: 00:00:00.49
# Mc/sec: 2078.76
//
Query:       EEA19226.1  [L=338]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
       0.59   11.2   7.2        1.3   10.0   7.2    1.5  1  zf-C2H2_assoc2  Unstructured region upstream of a zinc-finger
       0.63    9.2   8.1        3.9    6.7   3.5    2.1  2  ORC6            Origin recognition complex subunit 6 (ORC6)
        1.1    8.5   5.3        1.6    8.0   5.3    1.1  1  DUF908          Domain of Unknown Function (DUF908)


Domain annotation for each model (and alignments):
>> zf-C2H2_assoc2  Unstructured region upstream of a zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   7.2   0.00022       1.3       5      72 ..      15      81 ..      12      92 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00022
  zf-C2H2_assoc2  5 kgsnnvanstevkVkeEpsdevedidsspaislspqnelkgtnsaneKkstptaqkvkekeesespKa 72
                    ++ n+++ns++v V +  sde++d ++ p+  + ++  + +tn  n   s pt + +k ++ ++ p +
      EEA19226.1 15 HQFNEQNNSSQVSVHTHLSDEIDDKEEQPPAYTTSNI-AIQTNTENPPTSEPTQESSKFAQSQSKPMK 81
                    567889999***************8877766555544.68888889999************9999855 PP

>> ORC6  Origin recognition complex subunit 6 (ORC6)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   3.5   0.00065       3.9     117     196 ..       3      94 ..       2     127 .. 0.67
   2 ?    4.9   0.1    0.0022        13     311     347 ..     259     314 ..     248     319 .. 0.90

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.00065
        ORC6 117 PtKsktlktalsa....sksssplkrrrklaneedgeeeeedapswvstsir..dsrpeisrtlspskslgdesilfndss......ddekk 196
                 P Ks +   ++ +    +++ss  ++ + l +e d++ee++ a ++++  i+   ++p++s+++++s+++ ++++  +++       d++++
  EEA19226.1   3 PEKSNNPYFNSAHqfneQNNSSQVSVHTHLSDEIDDKEEQPPAYTTSNIAIQtnTENPPTSEPTQESSKFAQSQSKPMKKPiaipavDSTFD 94 
                 56666666665557777999999999999****99999988866666666666677777777777777777777755554444444444444 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.0022
        ORC6 311 eeWfrei...................ekkydyfdgaeeeesqakeskareglGsMl 347
                 ++W++++                   +kky+  +++e++ ++++e+++r+g+Gs l
  EEA19226.1 259 QPWIADLeldilpwtsqskltrfnaaLKKYNNIGDQEQKGKRRRERDSRQGFGSGL 314
                 689999999999999999999999999**************************976 PP

>> DUF908  Domain of Unknown Function (DUF908)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   5.3   0.00027       1.6     144     254 ..      10     127 ..       4     132 .. 0.56

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00027
      DUF908 144 YYkkssseeqkaesksskeeasesli.ssspstPtplrrssklgk.ts.sspsspaktstpskaaksqeglk..tfeipesevss.kslyellakave. 235
                 Y++++++ +++ +s++ +  +  s++ +++ + P p  ++s+    t+ ++p ++++t+++sk a+sq++     + ip+      +++   +a +++ 
  EEA19226.1  10 YFNSAHQFNEQNNSSQVSVHTHLSDEiDDKEEQP-PAYTTSNIAIqTNtENPPTSEPTQESSKFAQSQSKPMkkPIAIPAVDSTFdSPFIRAYAPILKd 107
                 6666666444443333333333333343333333.44444444332212333333333333333333333335688888876655266*********** PP

      DUF908 236 .kiPkesryellhririaka 254
                  k+P+e ++ +l r++ a +
  EEA19226.1 108 yKLPQEVFFSFLDRLNKAIS 127
                 ***************98865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (338 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       835  (0.0465726); expected 358.6 (0.02)
Passed bias filter:                      558  (0.0311228); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.56u 0.30s 00:00:00.86 Elapsed: 00:00:00.50
# Mc/sec: 2041.43
//
Query:       EEA19227.1  [L=482]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.6e-34  117.9  27.0    4.6e-34  117.9  27.0    1.3  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.9  27.0   2.6e-38   4.6e-34       1     352 [.      43     415 ..      43     418 .. 0.86
   2 ?   -4.2   0.2      0.33     6e+03     283     292 ..     436     445 ..     431     454 .. 0.43

  Alignments for each domain:
  == domain 1  score: 117.9 bits;  conditional E-value: 2.6e-38
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlga 99 
                 l+l++++s+l+r+++g a    l +d gi+ +++ + lt+++l+++ + lp   +  + ++r +l + ++++++ +++l f+ ++  ++++r+l G+++
  EEA19227.1  43 LALLFLCSFLDRTNVGNAKIVGLESDTGITDHQYDIGLTVFYLFYVCSELPSNLVLKKASPRIWLPFLAITWGIITMCLGFIRGFGSFVAVRALLGMAE 141
                 578999999999999999988******************************************************555558677779************ PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg......Wravfyilaivsllafvlfllllpeepperkrkspkeee.... 188
                 g+l+p+++ +++  +++++ ++ igl+++++sl+ ++g ll+  l++ +       Wr++f+i +++++++++++++ lp +  + +  +p+e+e    
  EEA19227.1 142 GGLLPGMVLYLSSFYKRSDLALRIGLFYTAASLSGAFGGLLARGLIEIGPrgglkgWRWIFIIEGLLTVVCGIIAAIGLPNNLATARFLTPIEREiale 240
                 **********************************************7766************************99***99999999999999999999 PP

       MFS_1 189 .............kgtgpaplvpawkallkdpvlw.illialllfffgfsglltllplylqevlgls...glllaglllallalvgailallagrlsdr 270
                              + ++p+ ++++++ +     +w +   a + +  g++++  +lp++   + g++   + +++   + ++++v+ ++ +l+++lsd+
  EEA19227.1 241 rirqdrpqhngsdAEHEPFRWSEVIRGVTDI-KMWlS-ASAYFAILSGLYSFGLFLPTI-IRDSGFTtnaNTVQLW--SVIPYAVATVFTVLVAFLSDH 334
                 9988888888655555666666633333333.35743.3333333447888*******7.********99669999..********************* PP

       MFS_1 271 lgrrrrlllallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfn.tagslggalg 352
                 ++   r +l+l+ l +a +g+a++a+ts+a +++ + +l+++gl   +p++l++ s++   ++  + +++++  + + gg+++
  EEA19227.1 335 FKL--RGTLMLFTLPFAIIGYAVIANTSNAQVGYGMTFLMSTGLYASVPCVLVWNSNNSAGHYKRATTSAMQlAIANCGGFVA 415
                 887..889999999999999*******9**************88889999999998888666666666666646666777776 PP

  == domain 2  score: -4.2 bits;  conditional E-value: 0.33
       MFS_1 283 llllaalgla 292
                 +ll+aa +l+
  EEA19227.1 436 GLLVAAWFLI 445
                 2222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (482 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       623  (0.0347482); expected 358.6 (0.02)
Passed bias filter:                      287  (0.0160076); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.46
# Mc/sec: 3182.02
//
Query:       EEA19228.1  [L=551]
Description: coenzyme A transferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   5.5e-103  343.0   1.4    2.5e-62  210.1   0.1    2.1  2  CoA_trans        Coenzyme A transferase
    0.00015   21.7   0.0     0.0004   20.3   0.0    1.7  1  AcetylCoA_hyd_C  Acetyl-CoA hydrolase/transferase C-terminal 
  ------ inclusion threshold ------
       0.11   11.9   0.1       0.63    9.5   0.0    2.0  2  Mannitol_dh_C    Mannitol dehydrogenase C-terminal domain


Domain annotation for each model (and alignments):
>> CoA_trans  Coenzyme A transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  210.1   0.1   4.2e-66   2.5e-62       3     216 ..      74     304 ..      72     305 .. 0.97
   2 !  132.3   0.1   2.6e-42   1.6e-38       3     215 ..     337     534 ..     335     536 .. 0.96

  Alignments for each domain:
  == domain 1  score: 210.1 bits;  conditional E-value: 4.2e-66
                 HHHHHHCTT--TTEEEEE-SBTTBTHHHHHHHHHHHHT...TTSEEEEESTTTE...ECCHHHHHTTTEEEEEESCTTBBCEHHHHHHHHTTSSEEEEH CS
   CoA_trans   3 taaeavakeikdGmtvavGGFgligiPealiaalarsg...vkdltviiseagv...lglgplllngsvkkviasyggetvnprfgkqflsgelefell 95 
                 +a++ava ++k+G+t++  GFgl+g +e+li+a+ar+g      l+ ++++agv    gl +l+ +g++ + i+s+ g+  n++++k++l g++ +el 
  EEA19228.1  74 SADDAVA-DLKSGSTILSAGFGLCGVAETLIQAIARRGardLHSLIAVSNNAGVakvGGLALLADAGQISRLIISFLGN--NKTLEKNYLTGKIAIELC 169
                 899****.******************************666666899*********99*********************..****************** PP

                 HHHHHHHHHHHHHHTEETTEEEESTTTTSHGGTT.................ESEEEEETTEEEEEEESSSEEEEEEECCEEETTCSEESSGGGHTTHSH CS
   CoA_trans  96 pqgtlaerlraGgaglpelgfltntgigtlvapk.................lkkvpgfgGaeyilepalkadvalikaskadeegnlvfeksagnfnkp 177
                 pqgt+aer+raGgag+p  +f+t+tg+ tl++++                 + +v++f+G+++++e+a++ dva+++a+kade+gn vf+ +++ f+ p
  EEA19228.1 170 PQGTIAERIRAGGAGIP--AFYTPTGVSTLLQEGripvrlssdgevlehgkKREVREFKGRKFLMEEAITGDVAILRAWKADEAGNCVFRYTTKAFG-P 265
                 *****************..********************************88********************************************.* PP

                 HHHHHEEEEEEEEEEEECTTSSECCCESBTGGGHSEEEE CS
   CoA_trans 178 aiaeaakvtileveeivekgkldpekvliPgvlvdavve 216
                  +a+aa  ti+e eeiv++g++dp+ v+ Pg++vd++v 
  EEA19228.1 266 IMAKAATLTIVESEEIVPVGSIDPNDVDLPGIFVDRIVP 304
                 *************************************95 PP

  == domain 2  score: 132.3 bits;  conditional E-value: 2.6e-42
                 HHHHHHCTT--TTEEEEE-SBTTBTHHHHHHHHHHHHTTTSEEEEESTTTEECCHHHHHTTTEEEEEESCTTBBCEHHHHHHHHTTSSEEEEHHHHHHH CS
   CoA_trans   3 taaeavakeikdGmtvavGGFgligiPealiaalarsgvkdltviiseagvlglgplllngsvkkviasyggetvnprfgkqflsgelefellpqgtla 101
                 ++a+++ake+k+G +v++G    +giP +l+++ ++    + + ++se+g+lg+gp++ + +v+ +i+++g+etv+ + g++ +++ ++f  +++g+++
  EEA19228.1 337 RIAKRAAKELKEGYYVNLG----VGIP-TLATSFLPE--GRTVWVQSENGILGMGPYPTKDEVDPDIVNAGKETVTLVPGASTFDSPESFG-MIRGGHV 427
                 6899999************....****.*********..9***************************************************.******* PP

                 HHHHHHHHTEETTEEEESTTTTSHGGTTESEEEEETTEEEEEEESS.SEEEEEEECCEEETTCSEESSGGGHTTHSHHHHHHEEEEEEEEEEEECTTSS CS
   CoA_trans 102 erlraGgaglpelgfltntgigtlvapklkkvpgfgGaeyilepal.kadvalikaskadeegnlvfeksagnfnkpaiaeaakvtileveeivekgkl 199
                 ++  +G++++  +g+l+n +i+    +k   ++g+gGa++++++++ +++v+   ++ +d+ +++v ++ ++ +++++++   ++t+l+v+e+++++ +
  EEA19228.1 428 DVSILGALQVAANGDLANYMIP----GK--VFKGMGGAMDLVSNPNnTKIVVATSHVAKDGSSKIVQRCDLPLTGAKCVS--TIITDLCVFEVDRENGE 518
                 **********************....77..8***********98862689999***************************..8**************** PP

                 ECCCESBTGGGHSEEE CS
   CoA_trans 200 dpekvliPgvlvdavv 215
                 + +++l Pgv vd++ 
  EEA19228.1 519 LALTELAPGVDVDEIR 534
                 **************96 PP

>> AcetylCoA_hyd_C  Acetyl-CoA hydrolase/transferase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0   6.7e-08    0.0004      36     121 ..     429     507 ..     406     524 .. 0.83

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 6.7e-08
                      EEEEE-SEEETTS-EESSECTTCCTCGGTTHHHHHHHHHHSTT-EEEEE--SEETTTTEESEESS-STTSSECE-TTT-SEEEETT CS
  AcetylCoA_hyd_C  36 vsinsalevdltGqvnseslggrvvsGvGgqldFvrgaalskggksiialpStakkgeiSrIvpslkegahvtttrhdvdyvvTEy 121
                      vsi  al+v  +G  +  ++ g+v+ G+Gg +d v++ ++    k ++a++ +ak+g+ S+Iv +++      t  + v++++T+ 
       EEA19228.1 429 VSILGALQVAANGDLANYMIPGKVFKGMGGAMDLVSNPNN---TKIVVATSHVAKDGS-SKIVQRCD---LPLTGAKCVSTIITDL 507
                      89999*******************************9988...566666666666676.*****999...6666677777777765 PP

>> Mannitol_dh_C  Mannitol dehydrogenase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.0    0.0001      0.63       4      41 ..     293     329 ..     290     353 .. 0.75
   2 ?   -0.3   0.0       0.1   6.1e+02     144     166 ..     467     489 ..     462     496 .. 0.88

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.0001
  Mannitol_dh_C   4 gfpntmVDRIvpaatddelakleeelgveDplavtvEp 41 
                      p   VDRIvpa+++++  ++++  +++ +   t E+
     EEA19228.1 293 DLPGIFVDRIVPATAEKHI-EIKKLREMNSGTSATKET 329
                    568889******8665555.999988888777777665 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.1
  Mannitol_dh_C 144 sNpyikdtvervaldGsqklpkr 166
                    +N +i  +++ va dGs+k+ +r
     EEA19228.1 467 NNTKIVVATSHVAKDGSSKIVQR 489
                    588899999**********9887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (551 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       335  (0.0186848); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.56u 0.25s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 3842.21
//
Query:       EEA19229.1  [L=768]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.2e-05   22.8   7.1    0.00016   21.7   7.1    1.6  1  Zn_clus          Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
       0.13   13.0   0.1        1.2    9.8   0.0    2.4  2  Vir_act_alpha_C  Virulence activator alpha C-term


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.7   7.1   1.8e-08   0.00016       2      34 ..      23      56 ..      22      62 .. 0.85

  Alignments for each domain:
  == domain 1  score: 21.7 bits;  conditional E-value: 1.8e-08
                S-HHHHHCT---STSSSS..-HHHHHCTHHHCCCC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPa..CsnCkklnleCtfys 34
                aC  C++kK KC++  ++  C +C + ++eC+ ++
  EEA19229.1 23 ACVLCHSKKLKCNRAPGQirCERCTQFRTECV-IP 56
                9*************555555***********9.55 PP

>> Vir_act_alpha_C  Virulence activator alpha C-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0   0.00014       1.2      14      46 ..      97     132 ..      95     158 .. 0.83
   2 ?   -0.5   0.0      0.24   2.1e+03      18      44 ..     457     483 ..     452     501 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00014
  Vir_act_alpha_C  14 vldpealieeLerrreeheekLaeyeeieerl...e 46 
                       +dp ++i +L++ +++++++La+ ++i + +   +
       EEA19229.1  97 GGDPVKVISHLQDLLDKAQRQLANRKQIVQPDssrS 132
                      57999***********************99986651 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.24
  Vir_act_alpha_C  18 ealieeLerrreeheekLaeyeeieer 44 
                      + l+++L + +++ ++  ++y++  + 
       EEA19229.1 457 AILRRDLDELLRKVRRACDDYRKTDNG 483
                      678999999999999999999976654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (768 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       673  (0.037537); expected 358.6 (0.02)
Passed bias filter:                      519  (0.0289475); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.26s 00:00:00.93 Elapsed: 00:00:00.45
# Mc/sec: 5155.10
//
Query:       EEA19230.1  [L=397]
Description: metallo-beta-lactamase domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.3e-17   62.8   0.9    7.2e-17   62.0   0.9    1.3  1  Lactamase_B    Metallo-beta-lactamase superfamily
    0.00022   20.8   0.1     0.0004   20.0   0.1    1.4  1  Lactamase_B_2  Beta-lactamase superfamily domain


Domain annotation for each model (and alignments):
>> Lactamase_B  Metallo-beta-lactamase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.0   0.9     8e-21   7.2e-17       9     197 .]     120     310 ..     114     310 .. 0.89

  Alignments for each domain:
  == domain 1  score: 62.0 bits;  conditional E-value: 8e-21
                  EEEE..ETTCEEEES--SCHHHHHHHH.......HHHHHTSGGGGEEEEE-SBSSHHHHTTGGGCTTHHCCEETCCEHHHHCCHCHHHHHHHHHCCHH CS
  Lactamase_B   9 ylie..gdggviLiDtGtsteaaraal.......elaalglkpkdvdavilTHlHlDHiGglgglveatdvpvgavaeeapalfmeeaddaasrkgll 97 
                  y++      ++i+iD+ ++ +a+ +         ++ + +++   vd ++ TH H+DHi ++ +l ++    +g  + ++   +   ++  +      
   EEA19230.1 120 YIVAdpSTLKAIIIDPVLDYDASTQTInthsadaLISLTKKNNYMVDMILETHVHADHITAASYLQNRLAKDQGLKPRIGIGKRIGQVQERFAQRY-- 215
                  56665555689*********************************************************9999998888876655555543333332.. PP

                  TTCHCGCCEEEEETTTEECCCTEEEEEHECTTSTSCCEEEEEETTCCEEEECTTTSSHHCCCCCC.TTCEEE-SHCHHHHHHHHHHHHHHHCHSEEEE CS
  Lactamase_B  98 lagvsadkpdvdeeeldgnaggrralyvtggpghghghgvveygggkvlftGDallagetgridltlrgaevrdpsdaekyldsllklaglkaevlvp 195
                  + ++ +  ++ d++ +d++ + +++l v  ++++gh++ +++y++g+ +f+GD l+  ++g+ ++      ++++++a ++ +s +kl +l   v + 
   EEA19230.1 216 GVPPEEYQDVYDILFYDDEIFKIGDLSVKAIHLPGHTPDHLGYKIGDNVFCGDSLFHVDIGTARC------DFPGGSANNLYNSGRKLLELGEHVKIW 307
                  57999999*********************************************************......********************9999888 PP

                  .SS CS
  Lactamase_B 196 .gH 197
                   gH
   EEA19230.1 308 tGH 310
                  888 PP

>> Lactamase_B_2  Beta-lactamase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   0.1   4.4e-08    0.0004       3     142 ..     131     268 ..     129     278 .. 0.71

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 4.4e-08
                    EEES--TT.......HHHHHTCGGS--S.SS--..SEEEEE-SS--HHHHGGGGCCCC..C--EE..EEEE.EEHHHHHHCCTTCGHHHCHTTTTE CS
  Lactamase_B_2   3 iLiDagpd.......lrqqalralqPve.lrdelppidaVllthaHyDHlaglltlre..lrpkk..lply.apkgvlavleanfvylaleeepav 85 
                    i+iD+++d       +  + + al   + ++++   +d++l th H+DH++ +  l+     +++   p +   k++++v e+  ++   ++e   
     EEA19230.1 131 IIIDPVLDydastqtINTHSADAL--ISlTKKNNYMVDMILETHVHADHITAASYLQNrlA-KDQglKPRIgIGKRIGQVQERFAQRYGVPPEEYQ 223
                    899999998865554222222222..3455666789**************99999999742.3335555553668888888888888877777444 PP

                    EEEEE-..TTSEEEECSTTEEEEEEEE-EE--CTCCE-TTTSEEEEEECTTEEEEEESS CS
  Lactamase_B_2  86 nvheld..wgesfelgdggleitatparhksgrrldrnagdtlGlriegggkrvyyigD 142
                    +v ++    +e f++g  +l+++a+ +++ ++          lG+ i+      +++gD
     EEA19230.1 224 DVYDILfyDDEIFKIG--DLSVKAIHLPGHTPD--------HLGYKIG----DNVFCGD 268
                    4544446689999999..689*******99999........8888888....5555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       463  (0.0258241); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 2715.03
//
Query:       EEA19231.1  [L=443]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.6e-12   46.6   0.0    2.7e-09   36.7   0.0    2.1  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
      0.002   18.2   0.0      0.013   15.5   0.0    2.0  2  NAD_binding_9  FAD-NAD(P)-binding
     0.0029   17.3   0.3      0.005   16.5   0.3    1.4  1  DAO            FAD dependent oxidoreductase
  ------ inclusion threshold ------
      0.037   13.1   0.2      0.086   11.9   0.2    1.6  2  FAD_binding_2  FAD binding domain
      0.094   11.8   0.0       0.19   10.8   0.0    1.5  1  Lycopene_cycl  Lycopene cyclase protein
      0.096   11.9   0.1        0.8    8.9   0.0    2.2  3  FAD_binding_3  FAD binding domain
       0.11   12.7   0.1       0.25   11.6   0.1    1.6  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain


Domain annotation for each model (and alignments):
>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.7   0.0   1.1e-12   2.7e-09       1     121 [.      32     155 ..      32     181 .. 0.77
   2 !    7.9   0.0   0.00061       1.6     184     289 ..     240     342 ..     232     349 .. 0.76

  Alignments for each domain:
  == domain 1  score: 36.7 bits;  conditional E-value: 1.1e-12
                  CSEEEE--SHHHHHHHHHHHH....HTS-EEEEETTHCHHHCSHHHHCHHHHHHHHHHHHHHHHHCHHHH.CCCCHCCTCEEEEESCEEEEETEEECT CS
                  xxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2   1 kdvvviGgGpAGlaaaltlaq....agakvtlvelegtclnggcllskallgvaedaeiasevvkklnqg.ielllgeevvkidpgkkkvklekkkeg 93 
                  ++vvv+GgG+AGla++++l +    ++ ++++v +  t+++ ++  + +  g + ++e ++  +++l  + ++++++  v ++ p+   v+l     +
   EEA19231.1  32 HKVVVVGGGAAGLAVSHQLLRngqfSQDDIAVV-DPATWHHYQPGWTLVGGGLKTKEELRR-PMDSLLDSkLKFYNE-GVATFAPEDNSVTL-----S 121
                  58*******************99888*******.999*********777766666666555.344444443888888.8888889999****.....6 PP

                  CEEEEEESEEEE---EEE-BCTCTTC.......T CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxx......xx RF
  Pyr_redox_2  94 deekiaydklvlAtGssprdlgipGv......ae 121
                  ++ k+ yd+lv+ +G s +   i+G+      ++
   EEA19231.1 122 NGGKLNYDHLVVVPGISVNFDSIKGLqealgnKD 155
                  7779***********6666556999844443333 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.00061
                  HHHHHHHHHHHHTTEEEEESCEEEEEEETTE...EEEEEETTSCEEEESEEEE-S-EEES-HHCSHCCT-EEEETTEEE--TTS.BES.STTEEE-GG CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxx.xxxxxxxxx RF
  Pyr_redox_2 184 elsaaleealekeGvevklgtsvkeidgnge...klevvledgeeidadlvvvavGvrpstelleeklglelderggivvdefl.rtn.vpgiyaiGD 276
                  + sa l+e ++++Gve  +++  ++i+gn+    +l+ +++  + +d   vv   G  +      +++ l+ d++g++ v++ + r n   +++ +GD
   EEA19231.1 240 KYSAKLNELRQERGVEGLFQHDLVAIEGNTAvfnRLDSKDQVTKHFDFLHVVPKMGPHAFV----KNSPLA-DQAGFVDVNQASlRHNkYGNVWSAGD 332
                  5688899999********************9444444455555558888888888877765....556665.79****99988778877********* PP

                  GCTECCSS--HHH CS
                  xxxxxxxxxxxxx RF
  Pyr_redox_2 277 vaggkggpelaqa 289
                       + p + +a
   EEA19231.1 333 AS---SLPTSKTA 342
                  88...44444443 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   5.2e-06     0.013       1      35 [.      35      68 ..      35      75 .. 0.92
   2 ?   -0.3   0.0      0.37   9.4e+02     116     153 ..     100     135 ..      90     137 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 5.2e-06
  NAD_binding_9  1 aivGaGprGlavlerLlarakkkspleitlfdpse 35
                   ++vG+G++Glav  +Ll++  + s+ +i ++dp++
     EEA19231.1 35 VVVGGGAAGLAVSHQLLRNG-QFSQDDIAVVDPAT 68
                   69*****************7.99*********975 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.37
  NAD_binding_9 116 tvevhraevvdleeradgqavlladgaslaadaVvLAl 153
                    +++++++ v   ++++++  v+l++g +l +d++v+  
     EEA19231.1 100 KLKFYNEGVATFAPEDNS--VTLSNGGKLNYDHLVVVP 135
                    566777777777777665..799**********99865 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.3   1.9e-06     0.005       1      29 [.      33      67 ..      33      83 .. 0.91

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 1.9e-06
                EEEEECTSHHHHHHHHHHHHTT......EEEEESS CS
         DAO  1 dvviiGGGiiGlstAyeLarrg......Vtllekg 29
                +vv++GGG +Gl++ ++L r g      +++++ +
  EEA19231.1 33 KVVVVGGGAAGLAVSHQLLRNGqfsqddIAVVDPA 67
                59****************999899999*****986 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.2   3.3e-05     0.086       2      23 ..      34      55 ..      33      66 .. 0.90
   2 ?   -3.0   0.0       1.1   2.8e+03      71      97 ..     178     204 ..     173     216 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 3.3e-05
                   EEEE--SHHHHHHHHHHHHTTT CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGl 23
                   v+V+G+G+AGLa ++++ ++G+
     EEA19231.1 34 VVVVGGGAAGLAVSHQLLRNGQ 55
                   9**************9999886 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.1
                    HHTTT-S-HHHHHHHHHTHHHHHHHHH CS
  FAD_binding_2  71 kaldeladqplveafveaapeavdeLe 97 
                    +++d l  qpl  + ++ ap++v +L+
     EEA19231.1 178 QGGDALFTQPLGVIKCAGAPQKVMWLA 204
                    677888899999999999999999996 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   7.3e-05      0.19       2      21 ..      34      53 ..      33      77 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 7.3e-05
  Lycopene_cycl  2 vvviGaGpAglslAarltea 21
                   vvv+G+G+Agl++ ++l ++
     EEA19231.1 34 VVVVGGGAAGLAVSHQLLRN 53
                   8***************9655 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.0   0.00031       0.8       3      24 ..      33      54 ..      31      74 .. 0.84
   2 ?   -2.5   0.0       0.9   2.3e+03      94     133 ..     228     267 ..     191     319 .. 0.74
   3 ?    0.2   0.0      0.13   3.4e+02     268     293 ..     309     334 ..     276     374 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00031
                   EEEEE--SHHHHHHHHHHHHTT CS
  FAD_binding_3  3 dVlIVGaGpaGlmlallLseaG 24
                   +V++VG+G aGl  ++ L + G
     EEA19231.1 33 KVVVVGGGAAGLAVSHQLLRNG 54
                   79****************9998 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.9
                    HCST-CEE--HHHHHHHHHHHHHHHTEEETCSEEEECCEE CS
  FAD_binding_3  94 sspervtvypqteleriLvehaeerglqvrfktevesleq 133
                    +  + + ++++++    L e ++erg++  f+++++++e 
     EEA19231.1 228 FATSLPGMFGVPKYSAKLNELRQERGVEGLFQHDLVAIEG 267
                    5566667777778888888888888888888888886654 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.13
                    EEEEEEEEEEESSSEETTEEE-GGGT CS
  FAD_binding_3 268 vsawtvaqrvaekyrkgrvflaGDAa 293
                    +  ++v+q   ++ + g+v  aGDA 
     EEA19231.1 309 AGFVDVNQASLRHNKYGNVWSAGDAS 334
                    55678999999*************96 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.1   9.6e-05      0.25       1      26 [.      36      65 ..      36      68 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 9.6e-05
                   EE--SHHHHHHHHHHHCC.TE...EEEEE- CS
  NAD_binding_8  1 IvGaGlsGlvaAylLaka.gf...dvllle 26
                   +vG+G++Gl+  + L ++ +f   d+ +++
     EEA19231.1 36 VVGGGAAGLAVSHQLLRNgQFsqdDIAVVD 65
                   8*************9998433444566665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (443 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       298  (0.0166211); expected 358.6 (0.02)
Passed bias filter:                      283  (0.0157845); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 3129.37
//
Query:       EEA19232.1  [L=574]
Description: CobW domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.3e-49  166.5   8.9    1.4e-36  125.8   0.2    2.6  3  cobW             CobW/HypB/UreG, nucleotide-binding domain
    3.2e-20   71.8   0.1    2.1e-15   56.4   0.0    2.6  2  CobW_C           Cobalamin synthesis protein cobW C-terminal 
    0.00067   19.2   0.1      0.081   12.5   0.0    2.5  2  GTP_EFTU         Elongation factor Tu GTP binding domain
     0.0078   16.6   0.4      0.041   14.3   0.4    2.3  1  AAA_16           AAA ATPase domain
  ------ inclusion threshold ------
      0.014   15.3   0.0      0.029   14.3   0.0    1.6  1  MobB             Molybdopterin guanine dinucleotide synthesis
       0.03   13.3   5.9        1.7    7.6   0.0    3.5  4  MeaB             Methylmalonyl Co-A mutase-associated GTPase 
      0.043   14.3   1.4       0.23   12.0   0.0    2.7  3  AAA_18           AAA domain
      0.056   13.4   0.0       0.14   12.2   0.0    1.6  1  TsaE             Threonylcarbamoyl adenosine biosynthesis pro
      0.063   13.3   0.0       0.12   12.4   0.0    1.4  1  Serine_rich      Serine rich protein interaction domain
      0.084   11.9   0.7       0.19   10.7   0.0    1.8  2  T2SSE            Type II/IV secretion system protein
      0.086   13.0   0.0       0.19   11.9   0.0    1.7  1  AAA_33           AAA domain
       0.12   12.1   0.0       0.21   11.3   0.0    1.4  1  Viral_helicase1  Viral (Superfamily 1) RNA helicase
       0.16   11.8   0.1        0.4   10.5   0.1    1.6  1  AAA_29           P-loop containing region of AAA domain
       0.37   11.3   2.5        1.4    9.4   0.1    2.6  3  AAA_23           AAA domain


Domain annotation for each model (and alignments):
>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  125.8   0.2   1.1e-39   1.4e-36       1     107 [.      11     125 ..      11     151 .. 0.88
   2 !   46.2   0.6   2.8e-15   3.6e-12     106     176 ..     155     244 ..     136     245 .. 0.93
   3 ?   -3.8   0.1       6.2     8e+03     116     131 ..     517     532 ..     507     539 .. 0.61

  Alignments for each domain:
  == domain 1  score: 125.8 bits;  conditional E-value: 1.1e-39
                 EEEEEEESTTCCHHHHHHHHH.CT--SS-EEEEESS-SSCHCCCCCCHCCCT......EEEETTTTECCHCTT-HHHHHHHHHHHHTT-SEEEEEECTT CS
        cobW   1 pvtvltGflGsGKTtLlnhll.enraglklavivNefgevsiDaellretgve.....ivelenGciCctlredllkelealeereerldviliEttGl 93 
                 pvt+l+GflGsGKTtLl+h+l +  +glk+avivN++ +++iDa+l+++++v+     +++l+nGciCctlr dll el++l++ ++ +d+++iE+tG+
  EEA19232.1  11 PVTLLSGFLGSGKTTLLEHILkSPDHGLKIAVIVNDMASLNIDAALISNHKVSqtrekLIQLQNGCICCTLRGDLLGELARLARSPGMVDYVVIESTGI 109
                 79*******************87889*********************88755556677***************************************** PP

                 TTHHHH..HTTSHHHH CS
        cobW  94 aePapv..afteeelk 107
                 +eP++v  +ft+e ++
  EEA19232.1 110 SEPMQVaeTFTAEFTA 125
                 ******6555544333 PP

  == domain 2  score: 46.2 bits;  conditional E-value: 2.8e-15
                 HHHCCCECEEEEEEETTTH.....................CCHCCHHHHHHHHHHTSSEEEEE-HHHHCHC..HHHHHHHHHHHHTTS-EE CS
        cobW 106 lksdltldavvavvDaknl....................eaeeekieekaedqlaaadllvlnKtDlldeeallekleerlrqlnpeakvl 176
                 l++ ++ld++v+v+Da nl                     ++e++i++++ dq+++ad++++nK+D +de+   e+++e +++lnp+akv+
  EEA19232.1 155 LQKLAKLDTTVTVIDAFNLfsnfhtaeflsdrygsdeiaAEDERTISDLMVDQIEFADVIIVNKIDSVDEKVR-ERIRELVKSLNPDAKVI 244
                 566789**********999*******************9899*****************************66.9*************997 PP

  == domain 3  score: -3.8 bits;  conditional E-value: 6.2
                 EEEEETTTH.CCHCCH CS
        cobW 116 vavvDaknleaeeeki 131
                 v vvD+++ e+e++++
  EEA19232.1 517 VDVVDVDEDEDEDKDK 532
                 6788885543222222 PP

>> CobW_C  Cobalamin synthesis protein cobW C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.8   0.0   6.5e-05     0.084       1      23 [.     303     325 ..     303     339 .. 0.88
   2 !   56.4   0.0   1.6e-18   2.1e-15      27      94 .]     386     476 ..     366     476 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 6.5e-05
      CobW_C   1 issfvfrarrpfdperleellee 23 
                 i+ fv++arrpf+p+rl +ll++
  EEA19232.1 303 INNFVYSARRPFHPRRLFALLHD 325
                 5789*****************98 PP

  == domain 2  score: 56.4 bits;  conditional E-value: 1.6e-18
      CobW_C  27 egilRaKGivwlagkpd.alvlqgvggrlrlepagawwaa......................ededrrseLVfIGrdldkealeeaLdacl 94 
                 +++lR+KG++wla+++    +++++gg l+++  g w  +                      +++drr+e+VfIG+++d+ ++ eaLd+cl
  EEA19232.1 386 GPVLRSKGFFWLATRSLqFGEWSQAGGILTVSCGGVWFCElpreiwpddkdiiqsierdfagQWGDRRQEIVFIGEGIDAHQISEALDECL 476
                 78*************999**************99999988**************************************************7 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.0     0.017        22      12      26 ..      19      33 ..      10     109 .. 0.86
   2 !   12.5   0.0   6.3e-05     0.081     122     166 ..     209     260 ..     156     360 .. 0.75

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.017
                TTSSHHHHHHHHHHH CS
    GTP_EFTU 12 vDhGKtTLtdrLlyk 26
                + +GKtTL++++l++
  EEA19232.1 19 LGSGKTTLLEHILKS 33
                568*********975 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 6.3e-05
                 TTEEEEEEESCGSTHHHHHHHHHHHHHHHHHH.......HHHHHHHHHTTT.......T CS
    GTP_EFTU 122 gvpiivfiNKmDrlkaelkeiveevkqklsrk.......eeklekygekge.......k 166
                 +   ++++NK+D ++++++e ++e+ ++l+ +                k +        
  EEA19232.1 209 EFADVIIVNKIDSVDEKVRERIRELVKSLNPDakvietsY-------SKVNvadivqtG 260
                 444799********************99955533333331.......222233333222 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.4   3.2e-05     0.041      25     145 ..      11     172 ..       2     244 .. 0.58

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 3.2e-05
      AAA_16  25 elvllsGesGvGKsslvrellralekd...............ggiflrgkcdqlesa..ipysa.laqalareellrqlldeaesaeleawrekleeal 105
                 +++llsG  G+GK++l++++l++                   ++ +++ + ++ +++  i ++   + +  r +ll +l                    
  EEA19232.1  11 PVTLLSGFLGSGKTTLLEHILKSPDHGlkiavivndmaslniDAALISNHKVSQTREklIQLQNgCICCTLRGDLLGEL-------------------- 89 
                 789******************8544335443333333333332222222222221111122222222222222232222.................... PP

      AAA_16 106 a...................................avpelagaea.......srllellkrll..allsrderplvlvlDdlq 145
                 a                                   a  el+++e        +r+le++++l   ++l++ +  +v v+D + 
  EEA19232.1  90 ArlarspgmvdyvviestgisepmqvaetftaeftaAMMELDPEELdstgqeeRRILEEVAELGglQKLAKLDT-TVTVIDAFN 172
                 22222222222333333333344444444444444533333333333334455666666666655555555444.666666665 PP

>> MobB  Molybdopterin guanine dinucleotide synthesis protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   2.3e-05     0.029       4      44 ..      15      54 ..      12     105 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2.3e-05
        MobB  4 ivgksgsGKTtLleklipelkarglrvgtiKhahhgfdvdk 44
                + g+ gsGKTtLle++++   ++gl++++i  +  ++++d 
  EEA19232.1 15 LSGFLGSGKTTLLEHILKS-PDHGLKIAVIVNDMASLNIDA 54
                67999**********9987.689*******99999999886 PP

>> MeaB  Methylmalonyl Co-A mutase-associated GTPase MeaB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   0.0    0.0013       1.7      34      77 ..      15      57 ..      11     164 .. 0.88
   2 ?    5.5   0.4    0.0058       7.4     166     194 ..     208     238 ..     200     261 .. 0.74
   3 ?   -2.1   0.0       1.2   1.5e+03     167     198 ..     252     283 ..     249     306 .. 0.79
   4 ?    0.6   0.4      0.18   2.3e+02     208     264 ..     492     549 ..     463     552 .. 0.75

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0013
                EEE-TTSSHHHHHHHHHHHHHCTT--EEEEEE------------ CS
        MeaB 34 ltGvPGaGkstlvealglelrrrGkrvavlavDPsspftGGsil 77
                l G+ G+Gk tl+e++  +  ++G ++av+  D +s     +++
  EEA19232.1 15 LSGFLGSGKTTLLEHIL-KSPDHGLKIAVIVNDMASLNIDAALI 57
                6899**********976.55899*******99998876666555 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.0058
                 HHH-SEEEEE---..HHHHHHHHHHHHHHHH CS
        MeaB 166 leiaDiivvnkaD..kkeaekaarelraale 194
                 +e aD+i+vnk D   +++++  rel + l+
  EEA19232.1 208 IEFADVIIVNKIDsvDEKVRERIRELVKSLN 238
                 79***********655555555555555554 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 1.2
                 HH-SEEEEE---HHHHHHHHHHHHHHHHHCST CS
        MeaB 167 eiaDiivvnkaDkkeaekaarelraaleleee 198
                 ++aDi+   k D  +a+  a +lr+  e++  
  EEA19232.1 252 NVADIVQTGKFDFVKAASGAGWLRSLHEMTMM 283
                 68999999999999999999999988777655 PP

  == domain 4  score: 0.6 bits;  conditional E-value: 0.18
                 EEEBCCCTBS.HHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
        MeaB 208 lktsavegeG.idelvdaieehrevlkktGllekrrrerakeelrelvedellkrvka 264
                  k+s  ++eG ++el++   e +  ++     e   ++++k+e++  v++++++r k 
  EEA19232.1 492 PKMSPAQKEGaLNELWEDGWEEWPDVDVVDVDEDEDEDKDKDEMQVDVQNDVSNRQKR 549
                 3677777777589****9999999999999999999****************999875 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   0.00018      0.23       2      51 ..      14      70 ..      14     105 .. 0.79
   2 ?   -2.1   0.0         4   5.1e+03      66      66 ..     236     236 ..     183     315 .. 0.64
   3 ?   -0.9   0.4       1.7   2.2e+03      39      69 ..     524     552 ..     504     568 .. 0.63

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00018
      AAA_18  2 lltGtpGvGKttlakeLskr..lgf..gvnlrdvakenglllevdpe...aldeskr 51
                ll+G  G+GKttl +++ k+  +g+   v+++d+a+ n       ++   +++e+++
  EEA19232.1 14 LLSGFLGSGKTTLLEHILKSpdHGLkiAVIVNDMASLNIDAALISNHkvsQTREKLI 70
                589**************6553323366999999999998888888885444444444 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 4
      AAA_18  66 e 66 
                  
  EEA19232.1 236 S 236
                 2 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 1.7
      AAA_18  39 levdpealdeskrldedkldklldaleenss 69 
                 +++d++  +++++++ d+++ +++  +++ s
  EEA19232.1 524 EDEDED--KDKDEMQVDVQNDVSNRQKRQVS 552
                 344444..67777777777777777776655 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00011      0.14      21      43 ..      12      34 ..       2      43 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00011
                EEEEEESTTSSHHHHHHHHHHHT CS
        TsaE 21 vilLeGdLGaGKTtlvrglakal 43
                v lL+G LG+GKTtl  +++k+ 
  EEA19232.1 12 VTLLSGFLGSGKTTLLEHILKSP 34
                579****************9875 PP

>> Serine_rich  Serine rich protein interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   9.3e-05      0.12      52     104 ..     200     252 ..     154     256 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 9.3e-05
  Serine_rich  52 lrtslrefleFargalanaaklsdknlqtkLrkqlqkledsdqilqetsqeLd 104
                  ++  + + +eFa+ +++n   + d+++ +++r++++ l+ +++++++++++ +
   EEA19232.1 200 ISDLMVDQIEFADVIIVNKIDSVDEKVRERIRELVKSLNPDAKVIETSYSKVN 252
                  666778899**********************************9998887765 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00015      0.19     132     178 ..      13      59 ..       3      76 .. 0.81
   2 ?   -1.7   0.2      0.91   1.2e+03      10      48 ..     196     235 ..     192     264 .. 0.58

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00015
       T2SSE 132 ilvsGgTgsGKttllyallkeinksderivtvEDpvEiqleganqvq 178
                  l+sG  gsGKttll  +lk  ++  +  v+v D + +++++a  ++
  EEA19232.1  13 TLLSGFLGSGKTTLLEHILKSPDHGLKIAVIVNDMASLNIDAALISN 59 
                 699*****************999997777899999999888765554 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.91
       T2SSE  10 ddekvsdihvekper..vkvrervdgielreveelekaale 48 
                 d++++sd++v + e   v++ +++d+ + ++v+e  +++++
  EEA19232.1 196 DERTISDLMVDQIEFadVIIVNKIDS-VDEKVRERIRELVK 235
                 56778888887766523334344444.33333333333333 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   0.00015      0.19       1      28 [.      12      44 ..      12     138 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00015
      AAA_33  1 lvllvGlpGsGKstlaerllkklg.....avll 28
                ++ll G  GsGK+tl+e++lk  +     av++
  EEA19232.1 12 VTLLSGFLGSGKTTLLEHILKSPDhglkiAVIV 44
                67899**************98776777743333 PP

>> Viral_helicase1  Viral (Superfamily 1) RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00017      0.21       2      28 ..      14      43 ..      13      78 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00017
  Viral_helicase1  2 vvhGvpGcGKStlirkllrts...liltvn 28
                     + +G+ G+GK+tl+ ++l++    l++ v+
       EEA19232.1 14 LLSGFLGSGKTTLLEHILKSPdhgLKIAVI 43
                     678***************998855333333 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.1   0.00031       0.4      23      39 ..      11      27 ..       3      32 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00031
      AAA_29 23 gatlltGpsGsGKSTll 39
                 +tll+G  GsGK+Tll
  EEA19232.1 11 PVTLLSGFLGSGKTTLL 27
                479*************9 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.1    0.0011       1.4      20      39 ..      11      30 ..       6      31 .. 0.91
   2 ?   -2.2   0.1       3.9     5e+03      91     123 ..     195     232 ..     138     255 .. 0.57
   3 ?    1.1   0.1      0.38   4.9e+02      87     143 ..     438     508 ..     335     552 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0011
      AAA_23 20 gltlItGpNGaGKTTildAi 39
                ++tl++G  G+GKTT+l+ i
  EEA19232.1 11 PVTLLSGFLGSGKTTLLEHI 30
                79***************987 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 3.9
      AAA_23  91 ererelskkkgkttkkaklellei.....deleqfise 123
                 e+er+ s+ + +++ +a+  ++++     ++ +++i+e
  EEA19232.1 195 EDERTISDLMVDQIEFADVIIVNKidsvdEKVRERIRE 232
                 33333333333333333333333332222222333333 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.38
      AAA_23  87 trsiererelskkkgkttkkaklelleideleqfisellgskki......ilnlilflgqer........f 143
                  +sier++  ++++ ++    ++e+++  +  + ++e l ++k+      i+++  + ++++        +
  EEA19232.1 438 IQSIERDFAGQWGDRRQEIVFIGEGIDAHQISEALDECLLNDKEmwqwerIMKNPKMSPAQKegalnelwE 508
                 57888899999999999999999999999999999999999999898888888888888887554444330 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (574 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       849  (0.0473534); expected 358.6 (0.02)
Passed bias filter:                      592  (0.0330191); expected 358.6 (0.02)
Passed Vit filter:                        82  (0.0045736); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.70u 0.32s 00:00:01.02 Elapsed: 00:00:00.48
# Mc/sec: 3563.31
//
Query:       EEA19233.1  [L=369]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-51  175.2   0.0    2.5e-51  175.0   0.0    1.0  1  TauD      Taurine catabolism dioxygenase TauD, TfdA family


Domain annotation for each model (and alignments):
>> TauD  Taurine catabolism dioxygenase TauD, TfdA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  175.0   0.0   1.4e-55   2.5e-51       8     267 ..      13     358 ..       6     359 .. 0.92

  Alignments for each domain:
  == domain 1  score: 175.0 bits;  conditional E-value: 1.4e-55
        TauD   8 k......fgae..gvdlsdleslddelkeelrellaeygvvvfrgfpl.speqqlefarrfG...............plygtpgrgtntkygevld... 79 
                 +      fg    gvdl++   l+de+++ + + l++  vvv++  p  s+++q e++rrf+                ++ +p+ +t +++++v++   
  EEA19233.1  13 AkgsaidFGSIitGVDLEN---LSDEDFQLIYDTLYRSSVVVIKSKPDvSAKAQYELTRRFDpsstayghgktidakRSILHPDLKTVPHQPQVQVign 108
                 4444555777755666666...999********************7555************99999999****************************** PP

        TauD  80 .vssvyesadianlayttll....................wHtDls.ylesppgiqlLhcleapa...........tG.......GetpfvDgraayna 138
                  + ++ye+ + ++l +++++                    wH D++ y  +pp ++ L ++  p+           +G       G t+fv+g+++y++
  EEA19233.1 109 gFIKEYEGLKDITLRHPHHRtfhreaipdeddldytrfyrWHIDAAlYDLDPPFVTTLLAVSLPSkrrqtlryddgSGdeldvslGTTAFVSGYQMYDR 207
                 *8888***************************************999****************999*999999977779999***************** PP

        TauD 139 Lpeelpellegltavrvyyhyrg................gglrteqelpavdkhprtghpvvrthpvltgrkallvnppfatri...eglgtpeskell 218
                 L+ee++e++++ ++++++++y++                g++    elp++d ++++++p+ +++pv tg+ al+v+p   ++i   +g   ++ +++ 
  EEA19233.1 208 LSEEDKEFVRTSKIEYAPHPYIWmsgarslptglglyseGRELAQSELPPIDPRKIKIFPMLWKNPV-TGKLALQVHPSAIKKIhlkDGTVIDDLEKVR 305
                 ***************************************9**************************8.*********766677744555555******* PP

        TauD 219 daleelled...peftyrfqwqeGdlvifdNrrvlHgrt.afdegeeRhllrc 267
                 d +++l+++   p+++y+++w+eGd+v+f+Nr+vlH+ + af+++e R +++c
  EEA19233.1 306 DIVYRLQRPgisPQYVYAHDWEEGDMVLFNNRGVLHSVVgAFAPDEVRLFRQC 358
                 ********9**99*****************************99999*99998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (369 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       320  (0.0178482); expected 358.6 (0.02)
Passed bias filter:                      314  (0.0175135); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.25s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2605.23
//
Query:       EEA19234.1  [L=685]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      1e-13   50.9   0.1    1.7e-13   50.2   0.1    1.3  1  Fungal_trans  Fungal specific transcription factor domain
    5.6e-08   32.8  11.5    1.2e-07   31.8  11.5    1.5  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.2   0.1   1.9e-17   1.7e-13       6     193 ..     226     411 ..     219     484 .. 0.77

  Alignments for each domain:
  == domain 1  score: 50.2 bits;  conditional E-value: 1.9e-17
  Fungal_trans   6 snfhpqfpilhkpsflpkt..ssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLlll 100
                    n++p   +lh p+  p +  + +n++++   +++l+++i+  + ++ ++ + +    + + s+  ++++    +l h   +   + + ++q+  ++
    EEA19234.1 226 NNVNPIVRLLHIPTTQPLFfaAVNNPTQTSADFSALIFSIYFAAVTSIDDSETYLILGQDRQSALNAYQCGLELSL-HMADFLDYPTIASIQAMSMY 321
                   457788899***99999999999************************99999998555555443333333333333.4455555555********** PP

  Fungal_trans 101 elyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrpp...llddsqinlpLPcddddlw 193
                    +++    + ++ + + g++vr ++ +gLhr+ ++ +      l++ e e+rrRlww + +lD ++a ++G  +    +++++++lpL  +d dl 
    EEA19234.1 322 LMCHRSHNSGRSGWVLNGLVVRASQCIGLHRDGEHFK------LSPLECEIRRRLWWHVMILDGRVAEDHGIITggyGNRCFDTKLPLNINDTDLT 411
                   *************************************......99999**************************8655899999999988888664 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.8  11.5   1.3e-11   1.2e-07       1      38 [.      28      63 ..      28      65 .. 0.92

  Alignments for each domain:
  == domain 1  score: 31.8 bits;  conditional E-value: 1.3e-11
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfysessk 38
                ++C++C+ +Kv+C++  P Cs C k++++C+ y+ + k
  EEA19234.1 28 RSCIRCHERKVRCNKAVP-CSACTKVGVQCR-YPGPEK 63
                59****************.************.987765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (685 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       555  (0.0309554); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.44
# Mc/sec: 4705.25
//
Query:       EEA19235.1  [L=433]
Description: monocarboxylate permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.9e-29  101.4  51.4    3.3e-22   78.9  22.4    2.0  2  MFS_1     Major Facilitator Superfamily
     0.0085   15.7   0.1     0.0085   15.7   0.1    2.1  3  SURF4     SURF4 family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.9  22.4   3.6e-26   3.3e-22      10     273 ..      56     306 ..      48     308 .. 0.79
   2 !   36.3  21.0   3.2e-13   2.9e-09      28     167 ..     273     416 ..     264     428 .. 0.81

  Alignments for each domain:
  == domain 1  score: 78.9 bits;  conditional E-value: 3.6e-26
       MFS_1  10 larsilgpalplalaedlg..ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll.fasslw.lllvlrvlqGlgagalfp 104
                 ++++++g++   +++++l   +s s+i ++ +l  ++++++ +++G l dr+G+r +ll+g ll ++g l+++ ++++++ +ll   v++++g +++f 
  EEA19235.1  56 AGSWCVGTFQN-YYQSTLLnqYSSSTIAWIPSLQIFFMFATGPIIGQLYDRYGPRYLLLVGSLLHVFG-LMMTsISTQYYqVLLSQGVVSAIGVATVFQ 152
                 45555444444.22222113499*********************************************.6666466999999***************** PP

       MFS_1 105 agaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeeekgtgpaplvpawkal 203
                  ++ +i  wf k +rg a+g++++g+s+G i+ p+    l+ ++g+ +++ i+a++ l ++ +  l +  + p+ +r+ ++ee        lv++++++
  EEA19235.1 153 PSLNVIPGWFDK-KRGIAYGIAASGSSIGGIIFPIMVQKLIVQVGYGWSMRIAAFMILGLLTISNLTIKSRFPPQPRSMTREE--------LVQPFREF 242
                 ************.*************************9999***99999999999999955533444444444444433333........55569999 PP

       MFS_1 204 lkdpvlwillialllfffgfsglltllpl.ylqevlglsglllaglllallalvgailallagrlsdrlgr 273
                  +      +++++ll +fg+++ + ++ +  l + ++ + l + +  la+l +++++++l+ag+l+d lg+
  EEA19235.1 243 NTVV----VICGFLLLTFGIFIPVDYVVVeALGTGMDPN-LAQYL--LAMLNAGSLFGRLIAGALADTLGA 306
                 9999....99************77777772345555555.66666..77777777788*********9986 PP

  == domain 2  score: 36.3 bits;  conditional E-value: 3.2e-13
       MFS_1  28 gispseigllltlyalgaavaslplGrlsdrfGrrr.vlllglllfalglllllfasslw.lllvlrvlqGlgagalfpagaaliadwfpk.eergrai 123
                 g++p  ++ ll++  +g++++ l++G+l+d +G+   + ++++++ +l  l+l++++s+  +++++ v+ G+++ga+++++a li++++p  +  g  +
  EEA19235.1 273 GMDPNLAQYLLAMLNAGSLFGRLIAGALADTLGAYNiFSFVCYVSGILV-LALWIPASSNaAVIAFAVIFGFTSGAYASLIANLIVKISPNfKVIGYRT 370
                 69999*******************************6666666666666.66664466666************************************** PP

       MFS_1 124 gllsagfslGailgpllgglla.sslgWravfyilaivsllafv.l 167
                 gl+ +++s+G + + +++g+++ +  g    + i+ +v+++a+  l
  EEA19235.1 371 GLAFLFASIGGLTTNPIAGAILqHDNGSYTGMKIFSGVCIMAGTtL 416
                 **************99999999544444445666666666665523 PP

>> SURF4  SURF4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.2      0.23   2.1e+03     153     183 ..     109     138 ..      91     152 .. 0.62
   2 !   15.7   0.1   9.4e-07    0.0085     176     251 ..     178     255 ..     170     257 .. 0.85
   3 ?   -3.2   0.3      0.54   4.8e+03     176     202 ..     347     373 ..     333     379 .. 0.72

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.23
       SURF4 153 sylllagrvllvlmfisllafelsftrvllt 183
                  ylll g +l v+ ++ ++     +++vll+
  EEA19235.1 109 RYLLLVGSLLHVFGLM-MTSISTQYYQVLLS 138
                 5788888877777655.34444457776643 PP

  == domain 2  score: 15.7 bits;  conditional E-value: 9.4e-07
       SURF4 176 sftrvlltiigvaliilvviGfktklaalvLvllLfvlnlvlna.fWtipkekelrdflk.YdffqtlsviGGLLlvv 251
                 s   ++  i+   li+ v  G+  ++aa+++  lL++ nl++ + f   p+  +  ++++ +  f t+ vi G+Ll++
  EEA19235.1 178 SIGGIIFPIMVQKLIVQVGYGWSMRIAAFMILGLLTISNLTIKSrFPPQPRSMTREELVQpFREFNTVVVICGFLLLT 255
                 5566888999999***************************998637778888888888765788**********9985 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 0.54
       SURF4 176 sftrvlltiigvaliilvviGfktkla 202
                 ++ +++ ++i  +   + viG++t la
  EEA19235.1 347 AYASLIANLIVKISPNFKVIGYRTGLA 373
                 577778888888788888999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (433 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       585  (0.0326287); expected 358.6 (0.02)
Passed bias filter:                      236  (0.013163); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.48
# Mc/sec: 2707.15
//
Query:       EEA19236.1  [L=304]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.2e-07   29.6   0.2    1.1e-06   29.0   0.2    1.3  1  PBP       Phosphatidylethanolamine-binding protein


Domain annotation for each model (and alignments):
>> PBP  Phosphatidylethanolamine-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.0   0.2     6e-11   1.1e-06      13     102 ..      80     161 ..      57     199 .. 0.73

  Alignments for each domain:
  == domain 1  score: 29.0 bits;  conditional E-value: 6e-11
                 -EEEEES--TTSSEEEEEEEETTSCCTCTT..EEEEEEEEEETTSSEE-TTCEE-B-TTSSCCCCS---B--STTS..EEEEEEEE.....EESSSG CS
         PBP  13 PplswsdvpegtksyalvviDpDapkvset..flHwvvtnipasvtslpegavqgknslgeesesgYlgpcPpkgdgkHrYvflly.....aldvea 102
                 P+l+ s+  +gt +y+++++Dp  + ++ t   lH + +n++a           g + ++    ++Y+ p P  g   H+Y +ll+     +++v++
  EEA19236.1  80 PSLTPSQ--NGTGKYVFIMVDPSTNATDPTypALHTLYVNVTA----------DGAEGWTI--LAPYINPEPTFGP-AHNYSLLLFeqpqaHFEVPS 161
                 5555555..79************9633333459********93..........44445555..67***********.7********65554444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (304 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       453  (0.0252663); expected 358.6 (0.02)
Passed bias filter:                      280  (0.0156172); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 2029.68
//
Query:       EEA19237.1  [L=440]
Description: 2-heptaprenyl-1,4-naphthoquinone methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.2e-77  260.9   0.0    1.8e-77  260.3   0.0    1.2  1  CMAS             Mycolic acid cyclopropane synthetase
    1.1e-14   54.8   0.0    2.5e-14   53.7   0.0    1.6  1  Methyltransf_25  Methyltransferase domain
    1.3e-13   51.4   0.0    3.4e-13   50.1   0.0    1.7  1  Methyltransf_11  Methyltransferase domain
    6.1e-12   45.7   0.0    1.3e-11   44.6   0.0    1.7  2  Methyltransf_23  Methyltransferase domain
    8.7e-08   32.1   0.0    1.8e-07   31.1   0.0    1.5  1  Methyltransf_31  Methyltransferase domain
      1e-07   32.6   0.0    2.8e-07   31.2   0.0    1.8  1  Methyltransf_12  Methyltransferase domain
    1.5e-05   24.6   0.0    2.9e-05   23.7   0.0    1.3  1  DOT1             Histone methylation protein DOT1
    7.8e-05   22.3   0.0    0.00013   21.6   0.0    1.3  1  MTS              Methyltransferase small domain
    0.00074   19.3   0.0     0.0012   18.7   0.0    1.2  1  PCMT             Protein-L-isoaspartate(D-aspartate) O-methyl
      0.003   17.5   0.0     0.0054   16.7   0.0    1.4  1  Methyltransf_18  Methyltransferase domain
  ------ inclusion threshold ------
      0.063   12.6   0.0      0.094   12.0   0.0    1.2  1  Methyltransf_2   O-methyltransferase domain
      0.074   12.0   0.0       0.11   11.4   0.0    1.2  1  Methyltransf_9   Protein of unknown function (DUF1698)
       0.13   11.7   0.0       0.22   11.0   0.0    1.3  1  Methyltransf_4   Putative methyltransferase


Domain annotation for each model (and alignments):
>> CMAS  Mycolic acid cyclopropane synthetase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  260.3   0.0   1.3e-80   1.8e-77       4     269 ..     131     414 ..     128     418 .. 0.88

  Alignments for each domain:
  == domain 1  score: 260.3 bits;  conditional E-value: 1.3e-80
                 XXXHHHHHHHHTS-HHHHCTTS-TT---S----SS.TT--HHHHHHHHHHHHHTTTT--TT-EEEEES-TTSHHHHHHHHHH--EEEEEES-HHHHHHH CS
        CMAS   4 kkevenikahYDlsndffalfldptmtYsCAyfer.ddmtLeeAqlaKldlileklelkpGmtlLdiGcGWGslvrraverydvkvvglTlSkeqakla 101
                 ++++ n +ahYD sn++fa+fl p+m YsCA+++  + +tL+ Aq++K+d++l+kl+l+  ++lLdiGcGWG ++++a+++y  +v g+TlS+eq  la
  EEA19237.1 131 QQARLNASAHYDTSNELFAAFLSPDMNYSCAHWTTdPAETLQTAQERKVDTLLKKLHLNSNHHLLDIGCGWGDVMIKAAQKYSCRVTGITLSSEQRSLA 229
                 56677999*************************863789************************************************************ PP

                 HHHHHTS-SSS-EEEEES-GGG---...--SEEEEES-GGGTSGGGHHHHHHHHHHHS-TT.-EEEEEEEEE--HHHHHCTTCCCHHHHHHTSTTS--- CS
        CMAS 102 kkrvdeldlerkvevklldyedlde...kvdrvvsvgafehvgkenydtffkklkkllked.GllllhtitslhkkelaerglklkfidkeiFPgGelp 196
                 ++rv+e+ l++ v+v+l+dy+  +     +dr+vs+g+fehvg + ++++f+ +++ll++   +l++ +it ++k + +   ++ +fi ++iFPgG+lp
  EEA19237.1 230 ENRVKEAKLQHLVSVLLCDYRTTPVpesGYDRIVSIGMFEHVGRKYLNEYFRIISRLLNPTtAVLVIDGITFTNKMHESRSPVD-TFIGRYIFPGGYLP 327
                 *********************86544479****************************987615667788888877777755555.************** PP

                 BHHHHHH...HHHHTT-EEEEEEE-HHHHHHHHHHHHHHHHHTHHHHHHHSH...........HHHHHHHHHHHHHHHHHHHTTSCE CS
        CMAS 197 sieeiee...eiseagftvvdveslrahYakTLkaWaealqenkdeaialvs...........eevarmyelYLagcaeaFrkgyid 269
                 si++++e   + s+  +++++v+++++hY kTL aW++++q+n+d ++a++            e + rm+ +Y+  c++ Fr++ +d
  EEA19237.1 328 SIHSLTEalhKGSKGTLEITHVRNIGPHYGKTLLAWRNNFQRNWDTIMANYMrkypsatgediEAFRRMWLYYFVSCEAGFRSRALD 414
                 ***9998554567889*******************************98753222333333345789****************9887 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.7   0.0   1.8e-17   2.5e-14       2      95 ..     195     289 ..     194     290 .. 0.97

  Alignments for each domain:
  == domain 1  score: 53.7 bits;  conditional E-value: 1.8e-17
                      EEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHHTTT..TEEEEESBCCGBSSSTTTEEEEEEESTGGGSSHHHHHHHHHHHHHHE CS
  Methyltransf_25   2 LdlGcGtGrltlalakrlgkakvtgvDiseemleaareraeeegl..nvefvqgdaedlpfedgsfDlvvssgalhhlsdedlekalkeiarvL 93 
                      Ld+GcG G++++++a+++ +++vtg+ +s+e+   a++r++e++l   v+++ +d ++ p +++ +D +vs+g+++h+ ++ l ++++ i+r+L
       EEA19237.1 195 LDIGCGWGDVMIKAAQKY-SCRVTGITLSSEQRSLAENRVKEAKLqhLVSVLLCDYRTTPVPESGYDRIVSIGMFEHVGRKYLNEYFRIISRLL 287
                      9****************9.6**********************99988999*********************999******************** PP

                      EE CS
  Methyltransf_25  94 kp 95 
                      +p
       EEA19237.1 288 NP 289
                      98 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.1   0.0   2.5e-16   3.4e-13       1      91 [.     195     290 ..     195     295 .. 0.95

  Alignments for each domain:
  == domain 1  score: 50.1 bits;  conditional E-value: 2.5e-16
                      EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-..EEEETTEECCCTSS-TT-EEEEEEES-CCC-..CCHHHHHHHHHHHEE CS
  Methyltransf_11   1 LdvGcGtGrlaealakrg.arvvgvDlskemlklakekaseegl..kvefvvadaeklpfednsfDlvvssevlhhv..edpekalkeiaRvLk 89 
                      Ld+GcG G ++ + a+++ +rv+g+ ls e++ la+++++e++l   v+++ +d +++p++++ +D +vs  +++hv  + ++++++ i R+L 
       EEA19237.1 195 LDIGCGWGDVMIKAAQKYsCRVTGITLSSEQRSLAENRVKEAKLqhLVSVLLCDYRTTPVPESGYDRIVSIGMFEHVgrKYLNEYFRIISRLLN 288
                      8**************8888***********************9999999********************************************9 PP

                      EE CS
  Methyltransf_11  90 pg 91 
                      p 
       EEA19237.1 289 PT 290
                      96 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.0       6.7   9.2e+03      27      40 ..      74      87 ..      71     100 .. 0.79
   2 !   44.6   0.0   9.5e-15   1.3e-11      10     118 ..     176     296 ..     167     371 .. 0.83

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 6.7
  Methyltransf_23 27 LdiGcGtGillevl 40
                     Ld+G+ + ++l+++
       EEA19237.1 74 LDLGTSEAYMLQEI 87
                     99999999999877 PP

  == domain 2  score: 44.6 bits;  conditional E-value: 9.5e-15
  Methyltransf_23  10 sdklerllpk..lraggrvLdiGcGtG.illevlrengfsvtgvDlspeaveiaekakkaqkdqfdeq.......eaaepqgkfdlIvlrevle 93 
                       +k++ ll+k  l+++  +LdiGcG G  + + ++++ + vtg+ ls+e+ ++ae++ k  k q+  +         ++p+  +d Iv++ ++e
       EEA19237.1 176 ERKVDTLLKKlhLNSNHHLLDIGCGWGdVMIKAAQKYSCRVTGITLSSEQRSLAENRVKEAKLQHLVSvllcdyrTTPVPESGYDRIVSIGMFE 269
                      45666666665589999**********555666688899****************999999999966655544444445999************ PP

  Methyltransf_23  94 hvp..dppellrqiatllkpgGyllls 118
                      hv   ++ e++r i +ll+p + +l+ 
       EEA19237.1 270 HVGrkYLNEYFRIISRLLNPTTAVLVI 296
                      **9667**************9766654 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.1   0.0   1.3e-10   1.8e-07       2     112 ..     189     298 ..     188     319 .. 0.89

  Alignments for each domain:
  == domain 1  score: 31.1 bits;  conditional E-value: 1.3e-10
  Methyltransf_31   2 dkglrvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielArenaqklgld.nveFeqgdieeleklledekfDlilsnevlnalad..pdk 92 
                      +++ ++lD+GCG G+  +++a++ +  ++v+Gi  s e  +lA+++ ++ +l+  v++  +d  + +  + ++ +D i+s + + ++    +++
       EEA19237.1 189 NSNHHLLDIGCGWGDVMIKAAQK-Y-SCRVTGITLSSEQRSLAENRVKEAKLQhLVSVLLCDYRTTP--VPESGYDRIVSIGMFEHVGRkyLNE 278
                      68999****************65.3.699************************99************..999************7765511699 PP

  Methyltransf_31  93 ileeiervlkpggilliedp 112
                      +++ i+r+l+p +++l+ d 
       EEA19237.1 279 YFRIISRLLNPTTAVLVIDG 298
                      ***************99876 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.2   0.0     2e-10   2.8e-07       1      95 [.     195     289 ..     195     293 .. 0.91

  Alignments for each domain:
  == domain 1  score: 31.2 bits;  conditional E-value: 2e-10
  Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvelealdlldldggssfDlvvasnvlhhl..kdirevldnirkl 92 
                      L+iGcG G+++   ++k   +++tg+ +s+++   a+++ ++ + ++   v l +       ++s +D +v+++ ++h+  k ++e+++ i +l
       EEA19237.1 195 LDIGCGWGDVMIKAAQK-YSCRVTGITLSSEQRSLAENRVKEAKLQHLVSVLLCDYRT-TPVPESGYDRIVSIGMFEHVgrKYLNEYFRIISRL 286
                      8*************999.9**************9********9999988877777774.455558***************************** PP

  Methyltransf_12  93 Lkp 95 
                      L+p
       EEA19237.1 287 LNP 289
                      *99 PP

>> DOT1  Histone methylation protein DOT1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.7   0.0   2.1e-08   2.9e-05      30      89 ..     178     236 ..     169     244 .. 0.91

  Alignments for each domain:
  == domain 1  score: 23.7 bits;  conditional E-value: 2.1e-08
                 HHHHHHHHTT--TT-EEEEES-TTSHHHHHHHHHH--SEEEEEE--HHHHHHHHHHHHHH CS
        DOT1  30 flsevldkvnlkkedvFvDLGSGvGnvvlqaalevgcklsvGvEimdnaselaekqkeel 89 
                  + ++l+k++l++++  +D+G G G+v+++aa ++ c+  +G+ ++ +  +lae++ +e 
  EEA19237.1 178 KVDTLLKKLHLNSNHHLLDIGCGWGDVMIKAAQKYSCR-VTGITLSSEQRSLAENRVKEA 236
                 57789*********************************.99*************998875 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.6   0.0   9.1e-08   0.00013      22     103 ..     181     264 ..     176     302 .. 0.81

  Alignments for each domain:
  == domain 1  score: 21.6 bits;  conditional E-value: 9.1e-08
                 HHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTT.STTS-EEEEEE CS
         MTS  22 lLletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvlee.veekkfdlivs 103
                  Ll++l+ + ++++lD+GcG+G + +++a++++  +vt +  + +   +a++ +++ kl+  v+v+ +d   + v+e  +d ivs
  EEA19237.1 181 TLLKKLHLNSNHHLLDIGCGWGDVMIKAAQKYSC-RVTGITLSSEQRSLAENRVKEAKLQhlVSVLLCDYRTTpVPESGYDRIVS 264
                 5999999999*******************98876.78888888888888888888888888899999998765266889999997 PP

>> PCMT  Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   8.4e-07    0.0012      62     148 ..     179     264 ..     157     278 .. 0.86

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 8.4e-07
                 HHHHHHHTT--TT-EEEEES-TTSHHHHHHHHHHCTTCEEEEEESBHHHHHHHHHHHHHCTTC.SEEEEES-GGGTTGGG-SEEEEEE CS
        PCMT  62 valalellelkkgarvLevGsGsGyltavlarlvgekgrvvsierikelveeakrnlkkldle.nvivvvgDGrkGyeekaPYdaihv 148
                 v ++l+ l+l+   + L++G+G G   +++    + ++rv +i  + e  + a++++k+ +l+  v+v   D r+   +++ Yd+i+ 
  EEA19237.1 179 VDTLLKKLHLNSNHHLLDIGCGWGD--VMIKAAQKYSCRVTGITLSSEQRSLAENRVKEAKLQhLVSVLLCDYRTTPVPESGYDRIVS 264
                 556778899***********99885..5666677889**********************9998578999****************974 PP

>> Methyltransf_18  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   3.9e-06    0.0054      13     101 ..     189     277 ..     181     296 .. 0.86

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 3.9e-06
  Methyltransf_18  13 ekgsrvaDiGtDHgylpiylvkegkakkviasDinegplekakeniekagledkievrlsdGleklkeee.vdtvviaGmGgelileILe 101
                      +++++++DiG+  g + i+++++  + +v+ + ++++  + a++ +++a+l++ ++v l+d  ++  +e+ +d +v  Gm  ++ ++ L+
       EEA19237.1 189 NSNHHLLDIGCGWGDVMIKAAQKYSC-RVTGITLSSEQRSLAENRVKEAKLQHLVSVLLCDYRTTPVPESgYDRIVSIGMFEHVGRKYLN 277
                      66789****************87777.899999****************************9998888888********97666665555 PP

>> Methyltransf_2  O-methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   6.8e-05     0.094      41     168 ..     169     299 ..     155     316 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 6.8e-05
                     HHHHTTHHHHHHHHHHSS-GGG-SEEEEET-TTSHHHHHHHHH-TT-EEEEEE-HH.HHHHHHHHS.-----TTEEEEES-TTTS-----SEEEE CS
  Methyltransf_2  41 kglqessslvakkvleafdleglkslvDvGGGtGalakaivsayPtikvivfDlpe.VveaAkehl.sageeervefvgGdffkdslPeaDaill 133
                     ++lq  ++  ++++l++ +l++ ++l+D+G G G ++ +++++y +++v+   l++   + A++++ +a++++ v++   d++  ++Pe+    +
      EEA19237.1 169 ETLQTAQERKVDTLLKKLHLNSNHHLLDIGCGWGDVMIKAAQKY-SCRVTGITLSSeQRSLAENRVkEAKLQHLVSVLLCDYRTTPVPESGYDRI 262
                     567778888899*************************9999999.57777777765145668888878999999999999999999997644333 PP

                     ESS.GGGS-HHH.HHHHHHHHHHH--TT-EEEEEE-- CS
  Methyltransf_2 134 krv.lhDwsdek.cvklLkrvkkalpagGkvivveav 168
                     +++ ++++   k  ++  + + + l++  +v+v++ +
      EEA19237.1 263 VSIgMFEHVGRKyLNEYFRIISRLLNPTTAVLVIDGI 299
                     3332555544431344555555555666666666655 PP

>> Methyltransf_9  Protein of unknown function (DUF1698)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   7.8e-05      0.11     101     236 ..     176     315 ..     171     353 .. 0.67

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 7.8e-05
                     HHHHHHHGGGS.--TT-EEEEET-TTSHHHHHHHHCT-SEEEEE---HHHHH.HHHHHHCCTTTTSSEEEE---GGGS-T.---EEEEEEES-GG CS
  Methyltransf_9 101 dwkWdrvlphlsdlkgrtildvGcgnGyhlwrmvgegaklvvGidPselfli.qfeavrkllgedqrahllplgieqlpe.leafdtvfsmGvly 193
                     ++k d +l+ l    ++ +ld+Gcg G  + + + + +  v Gi  s+       + v++    ++ + +l       p   +++d + s+G++ 
      EEA19237.1 176 ERKVDTLLKKLHLNSNHHLLDIGCGWGDVMIKAAQKYSCRVTGITLSSEQRSlAENRVKEAK-LQHLVSVLLCDYRTTPVpESGYDRIVSIGMFE 269
                     6889999999988899****************************976554440444444444.45555555466666666567899999999998 PP

                     G.-S-HHHHHHHHHCTEEEEEE..EEEEEE-BSS-TT-EE--SS-B CS
  Methyltransf_9 194 h.rrsPldhllqlkdqlvkgGe..lvletlvieGdenavlvPedry 236
                     h  r  l++  ++   l +  +  lv++ +      ++   P d++
      EEA19237.1 270 HvGRKYLNEYFRIISRLLNPTTavLVIDGITFTNKMHESRSPVDTF 315
                     8435667777666666665444114555555556666666666665 PP

>> Methyltransf_4  Putative methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00016      0.22       3      52 ..     192     240 ..     190     248 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00016
                     EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCTTSS CS
  Methyltransf_4   3 pvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkiealelkN 52 
                       +l+iGcG G+++++ A+k  ++ + Gi ++++    + +++++ +l+ 
      EEA19237.1 192 HHLLDIGCGWGDVMIKAAQKY-SCRVTGITLSSEQRSLAENRVKEAKLQH 240
                     5689************99887.6788888888877777777777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (440 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       400  (0.0223102); expected 358.6 (0.02)
Passed bias filter:                      381  (0.0212505); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 2964.42
//
Query:       EEA19238.1  [L=325]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.6e-42  143.3  10.0      9e-42  143.1  10.0    1.1  1  SUR7          SUR7/PalI family
  ------ inclusion threshold ------
      0.028   14.0   0.3      0.079   12.6   0.2    1.8  2  Phage_tail_3  Phage tail tube protein, TTP
       0.37   11.1   0.0       0.37   11.1   0.0    2.7  3  Sigma_reg_N   Sigma factor regulator N-terminal


Domain annotation for each model (and alignments):
>> SUR7  SUR7/PalI family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  143.1  10.0   1.5e-45     9e-42       2     212 .]      10     256 ..       9     256 .. 0.96

  Alignments for each domain:
  == domain 1  score: 143.1 bits;  conditional E-value: 1.5e-45
        SUR7   2 rlillflslaalilllfailgsi.knstpltsiylskfdlsgldlaqi................................gladvysfgvwgyC..... 62 
                 +li+ +l++a+l  l  +i++s+ +++   +++y++++dl++l+   +                                +++d+y++g+ gyC     
  EEA19238.1  10 VLIPWLLTIASLAWLSTVIISSVyTKQKSGNKLYFVRVDLANLTDPDVssqlssmaslalknlteakdllsdlqkaetesQIRDFYDIGFLGYCagnkt 108
                 58999********999999999878888889**********7777666899**********************************************99 PP

        SUR7  63 dnsdvnytkCskpkagypfdpleelnsesngkvd.lPsnlrktlsklnnltkalfilhiialvlsfislvvgllaicvspdnsrllsflnlllsvlsfl 160
                 +n d  +++Cs++k+ ++fdp++ ++ + +g+++ lP++l++ l+++ ++++++f+ ++ia++++f++++v++ a++     sr++s+l++l+s +s++
  EEA19238.1 109 SNGDYIVDYCSPAKPMFWFDPVTVWGLNGTGAEAlLPDALKDGLKAYEKASTWMFVAYVIAFAATFVEILVAISAFF-----SRIGSLLTSLISGVSTI 202
                 999999***************99999999999889******************************************.....***************** PP

        SUR7 161 atllaalldtllfvfvrkkin..lkefgikaslglkflafaWlalaaallvvif 212
                 +tlla++++t+lf+ + ++++  lke+ + + +g+  l f+Wla+a++l++ +f
  EEA19238.1 203 FTLLASITATALFITLDGVFTtsLKEYQVRSMIGTLLLVFTWLAVACSLVSGMF 256
                 *************************************************99876 PP

>> Phage_tail_3  Phage tail tube protein, TTP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       0.5     3e+03      52      95 ..      29      75 ..      22      84 .. 0.69
   2 ?   12.6   0.2   1.3e-05     0.079      15      54 ..     210     249 ..     197     254 .. 0.88

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.5
  Phage_tail_3 52 ipqvtevatsGGeqqfltyqf..LeD.drekqipTiksavsitltia 95
                  i+ v + ++sG+   f+ +    L D d   q+  + s +   lt a
    EEA19238.1 29 ISSVYTKQKSGNKLYFVRVDLanLTDpDVSSQLSSMASLALKNLTEA 75
                  67788888888888887765333777777777777666665555555 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 1.3e-05
  Phage_tail_3  15 aatattitleGidttdtavfpagsGtgsltkvsswveipq 54 
                   +ata  itl+G+ tt+++++ + s +g+l  v +w  +++
    EEA19238.1 210 TATALFITLDGVFTTSLKEYQVRSMIGTLLLVFTWLAVAC 249
                   456699******************************9998 PP

>> Sigma_reg_N  Sigma factor regulator N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   6.2e-05      0.37      22      65 ..      18      62 ..       6      75 .. 0.76
   2 ?   -3.4   3.0       2.1   1.3e+04      23      23 ..     194     194 ..     153     226 .. 0.64
   3 ?   -1.4   0.1       0.5     3e+03       3      25 ..     225     247 ..     223     261 .. 0.64

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 6.2e-05
  Sigma_reg_N 22 vlllifvil.vvtllylaekegnklrevlelaveitsPNvyvdsg 65
                 ++ l ++ + +++  y ++k+gnkl +v  ++ ++t+P+v  + +
   EEA19238.1 18 IASLAWLSTvIISSVYTKQKSGNKLYFVRVDLANLTDPDVSSQLS 62
                 34445555546777777**********************987544 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 2.1
  Sigma_reg_N  23 l 23 
                   
   EEA19238.1 194 S 194
                  1 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.5
  Sigma_reg_N   3 ilkkakrksilrivlislivlll 25 
                  +lk ++ +s++ + l++++ l +
   EEA19238.1 225 SLKEYQVRSMIGTLLLVFTWLAV 247
                  56777777777777777665443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (325 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1147  (0.0639746); expected 358.6 (0.02)
Passed bias filter:                      552  (0.0307881); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.34s 00:00:00.99 Elapsed: 00:00:00.55
# Mc/sec: 1792.51
//
Query:       EEA19239.1  [L=718]
Description: peptidase S41 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.4e-06   28.0   0.0    5.7e-06   26.0   0.0    2.1  2  Peptidase_S41  Peptidase family S41


Domain annotation for each model (and alignments):
>> Peptidase_S41  Peptidase family S41
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0      0.12   2.2e+03      29      45 ..     217     234 ..     201     291 .. 0.75
   2 !   26.0   0.0   3.2e-10   5.7e-06       3     117 ..     342     546 ..     340     572 .. 0.70

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.12
                    TSSEEEEE-TTB-.EBEH CS
  Peptidase_S41  29 nvkglilDlRnNg.GGll 45 
                     v++l++D  +N  GGl 
     EEA19239.1 217 MVNNLVIDGQGNSlGGLF 234
                    567788887777545554 PP

  == domain 2  score: 26.0 bits;  conditional E-value: 3.2e-10
                    EEEEES-BCC...............THHHHHHHHHHHHHHTTSSEEEEE-TTB-EBEHHHHHHHHHCCSSSSEEEE.EECTTSEEE.......... CS
  Peptidase_S41   3 Gyiripsfse...............ktkeelakalkelkkknvkglilDlRnNgGGlldeavelaslflddglivs.trgrdgkkk.......... 72 
                    +++ +p+f e                t+e++ +     +k++ k++i+D+ nNgGG + + ++l+s f+++++i s tr r ++ +          
     EEA19239.1 342 AVLGVPTF-EtsgsnlpddvlynfaITAEWFVQN--ATQKDGKKKIIIDMQNNGGGVVVSGYALLSVFFPNETIYSgTRFRAHEAMdfigtifnyg 434
                    56666666.2245555555555332333333222..233379****************************99997535666666669999999999 PP

                    ............................................................EEEHTCSS-S...............TT-BSSEEEEE CS
  Peptidase_S41  73 ............................................................kksktekase...............evqykgplvvL 93 
                                                                                +        +               +     ++++L
     EEA19239.1 435 nnsdnstvsryglavnalvqpdqtstfqnwdevygpyteagipvsalmaefnfadeanpvS--------NpinidgeggelnartPPFAPENIIIL 522
                    9999999999998888888888888888877777777777777777776655555554440........044445555555555577889999999 PP

                    E-TTBBTHHHHHHHHHHHTTSEEE CS
  Peptidase_S41  94 vnegsaSaseifagalkdngratl 117
                    +++++ S   +f+  + + g+ t+
     EEA19239.1 523 TDGRCSSTCTVFVDHMVSKGVKTV 546
                    999999999999866655555543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (718 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       397  (0.0221429); expected 358.6 (0.02)
Passed bias filter:                      299  (0.0166769); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.76u 0.38s 00:00:01.14 Elapsed: 00:00:00.59
# Mc/sec: 3695.15
//
Query:       EEA19240.1  [L=507]
Description: MFS transporter of unkown specificity [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-40  139.4  62.9    1.3e-39  136.1  62.6    2.4  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.082   12.9   5.0       0.39   10.7   0.2    3.5  4  DUF1422   Protein of unknown function (DUF1422)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  136.1  62.6   1.5e-43   1.3e-39       4     352 ..      45     446 ..      36     447 .. 0.86
   2 ?   -2.3   0.0      0.18   1.6e+03     152     178 ..     473     499 ..     468     506 .. 0.52

  Alignments for each domain:
  == domain 1  score: 136.1 bits;  conditional E-value: 1.5e-43
       MFS_1   4 aaflsalarsilgpalpl.alaedlg.ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa..sslwlllvlrvlqGlg 98 
                 a+f++ +a ++   + pl +++e++   +p  +++l+++y+l+ + ++l++Gr +d fG r +ll+g+ +f++++l++ ++  s++ l++++r lqGlg
  EEA19240.1  45 AQFMTQAALGAC--LSPLdIIGESFDvTNPGILSWLIAGYSLTVGTFILFFGRCGDLFGYRLMLLIGFSWFSVWSLVAGMGvySNYILFIFARTLQGLG 141
                 222222222222..225568899999667788******************************************7777775657777************ PP

       MFS_1  99 agalfpagaaliadwfpk.eergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee........ 188
                  ++lfp+g+a++ + +p+ +++ + ++l+++++  Ga++g+++++lla++ +W+++f+ +ai ++l++v+++l++  + +++++      +        
  EEA19240.1 142 PAMLFPNGLAILGATYPPgNKKRLIFALFGGMAPSGAVVGAVFAALLAELSWWPWIFWCMAIYCMLLAVIVYLVV--PSTPSHTADMSLTRileeldip 238
                 ******************56666666*****************************************99855555..44444444443334568999** PP

       MFS_1 189 ...............................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlgl 240
                                                                + + p+pl+p ++ l +d  +  +l ++++++  f + ++++  +l + +g+
  EEA19240.1 239 gaalgvaglilvniawnqapvvgwqkayvyvlliigflflaafiyyeVAVSPQPLIP-FETLNTDVCF--ILGCVACGWSSFGIWVFYTWRFLEDIRGI 334
                 *********************************************************.********66..777777777788889999999******** PP

       MFS_1 241 sglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllllvlvl.iGfglgfvfpsllalasdlappeeagtas 338
                 +  lla++ +  +a  g+++a+ +++l+ +l++ +++l+al++++++ +++a+ +  +++++l +v++l +  g+ + fp++++++sd ++++++g a+
  EEA19240.1 335 T-PLLAAAQFVPPAPSGLAAAFATAYLMGKLKPGWIMLIALSAFTIGNIFMAINPIGQTYWALTFVSLLvMPWGMDMSFPAATVILSDAVGRRNQGVAA 432
                 *.68888888888888888999***********************************9999999977772555************************** PP

       MFS_1 339 glfntagslggalg 352
                 +l++t+ + ++++g
  EEA19240.1 433 SLVTTVVNYSISIG 446
                 ********999998 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 0.18
       MFS_1 152 avfyilaivsllafvlfllllpeeppe 178
                 a+ y   +++ l++vl l++++ ++++
  EEA19240.1 473 AAQYTGIGLGGLGIVLSLFYVLKSARK 499
                 555555556666666544555444444 PP

>> DUF1422  Protein of unknown function (DUF1422)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0      0.33     3e+03      32      50 ..     108     125 ..      94     143 .. 0.68
   2 ?   10.7   0.2   4.4e-05      0.39       6      53 ..     161     210 ..     157     232 .. 0.79
   3 ?   -3.7   0.0       1.3   1.2e+04      32      53 ..     372     393 ..     363     397 .. 0.71
   4 ?    2.2   0.1      0.02   1.8e+02       8      36 ..     415     443 ..     409     455 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.33
     DUF1422  32 vpfsifplialvlavycly 50 
                 + fs f++ +lv     +y
  EEA19240.1 108 IGFSWFSVWSLVAG-MGVY 125
                 56777777776632.2333 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 4.4e-05
     DUF1422   6 ekktllLaliaGlslngt.lsalfsslv.pfsifplialvlavyclyqrY 53 
                 +kk l+ al  G++  g+ + a+f +l+ + s +p i  ++a+yc+    
  EEA19240.1 161 NKKRLIFALFGGMAPSGAvVGAVFAALLaELSWWPWIFWCMAIYCMLLAV 210
                 6999**********8876156788887658***************97655 PP

  == domain 3  score: -3.7 bits;  conditional E-value: 1.3
     DUF1422  32 vpfsifplialvlavyclyqrY 53 
                 ++ s f +  + +a+  + q Y
  EEA19240.1 372 IALSAFTIGNIFMAINPIGQTY 393
                 5667777777777777776666 PP

  == domain 4  score: 2.2 bits;  conditional E-value: 0.02
     DUF1422   8 ktllLaliaGlslngtlsalfsslvpfsi 36 
                  t++L+  +G   +g+ + l++++v++si
  EEA19240.1 415 ATVILSDAVGRRNQGVAASLVTTVVNYSI 443
                 69999999********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (507 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       915  (0.0510346); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.31s 00:00:00.88 Elapsed: 00:00:00.45
# Mc/sec: 3354.69
//
Query:       EEA19241.1  [L=95]
Description: ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.9e-33  114.2   0.2    2.2e-33  114.0   0.2    1.0  1  UcrQ        UcrQ family
     0.0068   16.8   0.0     0.0088   16.4   0.0    1.2  1  Cyt_b-c1_8  Cytochrome b-c1 complex subunit 8


Domain annotation for each model (and alignments):
>> UcrQ  UcrQ family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.0   0.2   2.5e-37   2.2e-33       2      77 ..      16      91 ..      15      92 .. 0.96

  Alignments for each domain:
  == domain 1  score: 114.0 bits;  conditional E-value: 2.5e-37
                TTB-S----BSEEEEEE-GGGB-SSTTTTTTSSSSTTCTTTTTHHHHHHHHHHHHHHHHHHHHHHHHHTSGGGHHH CS
        UcrQ  2 fGnlgspkqkgiitYslSPfeqkafagalskaifntlrRtksqvlyvlppfiiayliykwakeeneylnrKagrde 77
                +G   + + kg+ tY+lSP++q+ f+++++ aifnt+rR+++qvlyv+ppfi+ay +++wa e+neyln+Kagr+e
  EEA19241.1 16 WGGHIARPEKGVATYTLSPNRQRLFPNFWHTAIFNTFRRFRHQVLYVAPPFIVAYSLMDWAVERNEYLNSKAGRAE 91
                88888799******************************************************************87 PP

>> Cyt_b-c1_8  Cytochrome b-c1 complex subunit 8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0   9.8e-07    0.0088      12      55 ..      29      69 ..      25      84 .. 0.75

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 9.8e-07
  Cyt_b-c1_8 12 vYtlSPmqqkvmrglfkdlpkkiakkvkenwvsavlllvplvGt 55
                +YtlSP++q  ++  ++ +  ++ ++++    + + ++ p++  
  EEA19241.1 29 TYTLSPNRQRLFPNFWHTAIFNTFRRFRH---QVLYVAPPFIVA 69
                8*****************99999999954...444445555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (95 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       248  (0.0138323); expected 358.6 (0.02)
Passed bias filter:                      214  (0.011936); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.37u 0.26s 00:00:00.63 Elapsed: 00:00:00.41
# Mc/sec: 687.50
//
Query:       EEA19242.1  [L=134]
Description: ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.8e-33  112.9   0.2    6.5e-33  112.5   0.2    1.2  1  UcrQ        UcrQ family
  ------ inclusion threshold ------
      0.011   16.2   0.0       0.02   15.3   0.0    1.5  1  Cyt_b-c1_8  Cytochrome b-c1 complex subunit 8


Domain annotation for each model (and alignments):
>> UcrQ  UcrQ family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.5   0.2   7.2e-37   6.5e-33       2      77 ..      55     130 ..      54     131 .. 0.96

  Alignments for each domain:
  == domain 1  score: 112.5 bits;  conditional E-value: 7.2e-37
                 TTB-S----BSEEEEEE-GGGB-SSTTTTTTSSSSTTCTTTTTHHHHHHHHHHHHHHHHHHHHHHHHHTSGGGHHH CS
        UcrQ   2 fGnlgspkqkgiitYslSPfeqkafagalskaifntlrRtksqvlyvlppfiiayliykwakeeneylnrKagrde 77 
                 +G   + + kg+ tY+lSP++q+ f+++++ aifnt+rR+++qvlyv+ppfi+ay +++wa e+neyln+Kagr+e
  EEA19242.1  55 WGGHIARPEKGVATYTLSPNRQRLFPNFWHTAIFNTFRRFRHQVLYVAPPFIVAYSLMDWAVERNEYLNSKAGRAE 130
                 88888799******************************************************************87 PP

>> Cyt_b-c1_8  Cytochrome b-c1 complex subunit 8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.3   0.0   2.2e-06      0.02      12      53 ..      68     106 ..      64     123 .. 0.75

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 2.2e-06
  Cyt_b-c1_8  12 vYtlSPmqqkvmrglfkdlpkkiakkvkenwvsavlllvplv 53 
                 +YtlSP++q  ++  ++ +  ++ ++++    + + ++ p++
  EEA19242.1  68 TYTLSPNRQRLFPNFWHTAIFNTFRRFRH---QVLYVAPPFI 106
                 8*****************99999999954...4444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (134 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       222  (0.0123822); expected 358.6 (0.02)
Passed bias filter:                      186  (0.0103743); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.36u 0.26s 00:00:00.62 Elapsed: 00:00:00.41
# Mc/sec: 977.00
//
Query:       EEA19243.1  [L=81]
Description: ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.7e-26   91.9   0.6      2e-26   91.7   0.6    1.0  1  UcrQ        UcrQ family
      0.007   16.7   0.0     0.0091   16.4   0.0    1.2  1  Cyt_b-c1_8  Cytochrome b-c1 complex subunit 8


Domain annotation for each model (and alignments):
>> UcrQ  UcrQ family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.7   0.6   2.2e-30     2e-26       2      66 ..      16      80 ..      15      81 .] 0.96

  Alignments for each domain:
  == domain 1  score: 91.7 bits;  conditional E-value: 2.2e-30
                TTB-S----BSEEEEEE-GGGB-SSTTTTTTSSSSTTCTTTTTHHHHHHHHHHHHHHHHHHHHHH CS
        UcrQ  2 fGnlgspkqkgiitYslSPfeqkafagalskaifntlrRtksqvlyvlppfiiayliykwakeen 66
                +G   + + kg+ tY+lSP++q+ f+++++ aifnt+rR+++qvlyv+ppfi+ay +++wa e++
  EEA19243.1 16 WGGHIARPEKGVATYTLSPNRQRLFPNFWHTAIFNTFRRFRHQVLYVAPPFIVAYSLMDWAVERY 80
                88888799*****************************************************9986 PP

>> Cyt_b-c1_8  Cytochrome b-c1 complex subunit 8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0     1e-06    0.0091      12      42 ..      29      59 ..      25      79 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 1e-06
  Cyt_b-c1_8 12 vYtlSPmqqkvmrglfkdlpkkiakkvkenw 42
                +YtlSP++q  ++  ++ +  ++ ++++ + 
  EEA19243.1 29 TYTLSPNRQRLFPNFWHTAIFNTFRRFRHQV 59
                8*****************9999999995443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (81 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       279  (0.0155614); expected 358.6 (0.02)
Passed bias filter:                      225  (0.0125495); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.32u 0.27s 00:00:00.59 Elapsed: 00:00:00.40
# Mc/sec: 603.89
//
Query:       EEA19244.1  [L=314]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.1e-23   80.7   0.0    4.9e-22   78.3   0.0    1.9  2  adh_short       short chain dehydrogenase
    1.1e-11   44.8   0.0    2.2e-11   43.8   0.0    1.4  1  adh_short_C2    Enoyl-(Acyl carrier protein) reductase
    1.9e-09   37.7   0.0    2.5e-09   37.3   0.0    1.3  1  KR              KR domain
    1.1e-06   28.3   0.0    1.8e-06   27.6   0.0    1.3  1  Epimerase       NAD dependent epimerase/dehydratase family
    0.00041   19.9   0.0      0.002   17.6   0.0    1.9  1  GDP_Man_Dehyd   GDP-mannose 4,6 dehydratase
  ------ inclusion threshold ------
      0.068   12.5   0.0       0.12   11.6   0.0    1.4  1  Methyltransf_2  O-methyltransferase domain


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.3   0.0   1.7e-25   4.9e-22       1     137 [.      14     156 ..      14     166 .. 0.93
   2 ?   -0.2   0.0      0.19   5.6e+02     145     187 ..     178     229 ..     170     233 .. 0.69

  Alignments for each domain:
  == domain 1  score: 78.3 bits;  conditional E-value: 1.7e-25
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT..TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCS CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee..gakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfsels 97 
                 kv +vtG+ sGIG+ ++ +la+ Ga+v++++rs ek ++++k +k++  +ak++ +++D  d ++v a+ ++  +k   l+ LvnNAGi   +pf e++
  EEA19244.1  14 KVYIVTGGNSGIGYYTVARLAQHGAQVYMCARSLEKGNTAIKRIKQLypQAKITLLRIDHLDLSSVVAAAKQFLSKETALHGLVNNAGI-MATPF-EIT 110
                 7889********************************************999**************************************.45555.899 PP

                 HHHHHHHHHHHTHHHHHHHHHHHHHHH......HCTTEEEEEEEEG CS
   adh_short  98 eeewervievNltgvflltravlpaml......kqssGrIvnvsSv 137
                 ++ +e+  ++N  +    t ++lp ml       + + r+vnvsS 
  EEA19244.1 111 KDGYEAQWQTNHLAHWVFTSHLLPRMLrtsqtlPKGGVRVVNVSSS 156
                 999************************887765556669*****96 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.19
                 TBHHHHHHHHHHHHHHHHHHHHHGGGT.........EEEEEEEESSBSSHHH CS
   adh_short 145 gvaaYsAsKaavagltrslakelaptg.........irvnavaPGlvdTdma 187
                 ++a Y+ sK a +  +++l++ + p +         i +++v+PGlv++++ 
  EEA19244.1 178 SMARYGQSKLANVLHIKTLHNLYGPGSptatsgqgeIWCSIVHPGLVESNLG 229
                 6777888888888888888777765444444456668888888888888776 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.8   0.0   7.3e-15   2.2e-11       4     130 ..      23     157 ..      18     166 .. 0.87

  Alignments for each domain:
  == domain 1  score: 43.8 bits;  conditional E-value: 7.3e-15
                   TSHHHHHHHHHHHTT-EEEEEESSGGH.HHHHHHHHHHTTSE.E..EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHH CS
  adh_short_C2   4 sgIGraiAkalaeeGaevvltdlneea.kkrveelaeelgae.v..lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreefd 96 
                   sgIG+ ++ +la++Ga+v ++ ++ e+ + +++++++ ++++ +  l++D  d ++v a++++  +k   l++lvnnagi+ +      e+++++++
    EEA19244.1  23 SGIGYYTVARLAQHGAQVYMCARSLEKgNTAIKRIKQLYPQAkItlLRIDHLDLSSVVAAAKQFLSKETALHGLVNNAGIMAT----PFEITKDGYE 115
                   8***********************9999999999999998665567************************************9....589999**** PP

                   HHHHHHTHHHHHHHHHHHH.HCTSC.......CEEEEEEEGG CS
  adh_short_C2  97 raldvnlyslfllakaalp.lmkeg.......gsivnlssvg 130
                      ++n  + + ++ ++lp +++ +        ++vn+ss g
    EEA19244.1 116 AQWQTNHLAHWVFTSHLLPrMLRTSqtlpkggVRVVNVSSSG 157
                   ***********9999999954433345666555688888875 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.3   0.0   8.4e-13   2.5e-09       2      94 ..      15     105 ..      14     194 .. 0.86

  Alignments for each domain:
  == domain 1  score: 37.3 bits;  conditional E-value: 8.4e-13
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE------- CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrd 94 
                 +y++tGG  g+G  ++  la++ga+ + +++Rs ++ +++ ++i++l   +a+++++++D  d ++v a+ +++ ++e +++G ++ Ag++++
  EEA19244.1  15 VYIVTGGNSGIGYYTVARLAQHGAQ-VYMCARSLEKGNTAIKRIKQLYP-QAKITLLRIDHLDLSSVVAAAKQFLSKETALHGLVNNAGIMAT 105
                 7**********************95.8999***7777777777777765.89*************************************9975 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.6   0.0   5.9e-10   1.8e-06       2     161 ..      17     201 ..      16     209 .. 0.73

  Alignments for each domain:
  == domain 1  score: 27.6 bits;  conditional E-value: 5.9e-10
                 EEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC........EEEE--TT-HHHHHHHHHHH.....T-SEEEE--S---HHHHHHSHHHH CS
   Epimerase   2 lVtGatGfiGsalvkallekgyevigldrlssasntarledl........elveldltdrsalerlfkee.....qpdavihlAavggvaassedpadf 87 
                 +VtG++  iG ++v +l+++g +v   +r  +++nta ++ +        +l ++d +d s++ ++ k++     + +  ++ A+   ++a+  + ++ 
  EEA19244.1  17 IVTGGNSGIGYYTVARLAQHGAQVYMCARSLEKGNTAIKRIKqlypqakiTLLRIDHLDLSSVVAAAKQFlsketALHGLVNNAG---IMATPFEITKD 112
                 7*****************************99999998777789******88888888888666555555410034455555555...44443333333 PP

                 HHHHTHHHHHHHHHHH................HHTCTEEEEEEEGGGGTSCSSSSBSTCSTTS----SSHHHHHHHHHHHHHHHHHHHHT CS
   Epimerase  88 ieknlqgtlnlleaar................kagvkrllflsSsevYGkdaeqpkeettltgplkpnspYaaaKlageklveayaaqyg 161
                  ++    t +l+++++                k gv+ +   sS +++G+++ + +  +t     ++   Y+ +Kla    ++ +++ yg
  EEA19244.1 113 GYEAQWQTNHLAHWVFtshllprmlrtsqtlpKGGVRVVNVSSSGHWFGPKNGI-DFADTSLRDANSMARYGQSKLANVLHIKTLHNLYG 201
                 333333344555555566677999999988877799555555669********8.55555455669***********9999988888775 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   6.7e-07     0.002       1     168 [.      17     197 ..      17     207 .. 0.58

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 6.7e-07
                    EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TT..HHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHHHH.....T-SEEEE--S---HH CS
  GDP_Man_Dehyd   1 LiTGiaGfiGsylaelLlekgyevhgivrrsssfnt..griehlakdpkeeleenlklhkgDltDssslerllaev.....qpdevynLAAqshVd 89 
                    ++TG++  iG y++ +L + g +v+   r  ++ nt  +ri++l+       + +++l + D  D ss+  + ++        +  +n A+  + +
     EEA19244.1  17 IVTGGNSGIGYYTVARLAQHGAQVYMCARSLEKGNTaiKRIKQLYP------QAKITLLRIDHLDLSSVVAAAKQFlsketALHGLVNNAGIMATP 106
                    59************************99977776652268888874......35789999999998888765543311111555566666665555 PP

                    HHTTSH..HHHHHHHTHH....HHHHHHHHHHC.T....TTSEEEEEEEG.GGG-S-SSSSB-TTS-----SH..HHHHHHHHHHHHHHHH CS
  GDP_Man_Dehyd  90 vsfekP..eytaevnvlG....tlrLLeairal.gl..ekkvrfyqaSts.EvYGkvqevpqtEttpfyPrsP..YaaaKlyadwivvnyr 168
                      ++k   e+ +++n l+    t +LL  + ++ +   +  vr++ +S+s   +G  + + + +t   +++s   Y+ +Kl+    ++  +
     EEA19244.1 107 FEITKDgyEAQWQTNHLAhwvfTSHLLPRMLRTsQTlpKGGVRVVNVSSSgHWFGPKNGIDFADTSLRDANSMarYGQSKLANVLHIKTLH 197
                    5554431133444555442222444554443321221123466666665523466666666655544443332226666666665555555 PP

>> Methyltransf_2  O-methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   4.1e-05      0.12      76     109 ..      53      91 ..      49     114 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 4.1e-05
                     HHHHHHHH-TT-EEEE.....EE-HHHHHHHHHHS---- CS
  Methyltransf_2  76 lakaivsayPtikviv.....fDlpeVveaAkehlsage 109
                     ++k i ++yP+ k+++     +Dl++Vv+aAk++ls ++
      EEA19244.1  53 AIKRIKQLYPQAKITLlridhLDLSSVVAAAKQFLSKET 91 
                     5799********9997333336************96543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (314 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       511  (0.0285013); expected 358.6 (0.02)
Passed bias filter:                      456  (0.0254337); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2238.97
//
Query:       EEA19245.1  [L=293]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.1e-18   65.0   0.3    6.1e-18   65.0   0.3    1.6  2  DUF3425   Domain of unknown function (DUF3425)
  ------ inclusion threshold ------
       0.13   12.3   0.1        0.3   11.1   0.1    1.6  1  HTH_15    Helix-turn-helix domain of alkylmercury lyase


Domain annotation for each model (and alignments):
>> DUF3425  Domain of unknown function (DUF3425)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.1       1.1   9.6e+03      36      51 ..     131     146 ..     129     148 .. 0.82
   2 !   65.0   0.3   6.8e-22   6.1e-18      14     119 ..     172     270 ..     162     274 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 1.1
     DUF3425  36 eidvlpwpelRdrllr 51 
                  i +l +  lR  l++
  EEA19245.1 131 LILLLQYNVLRATLIN 146
                 6778999999999996 PP

  == domain 2  score: 65.0 bits;  conditional E-value: 6.8e-22
     DUF3425  14 aveklpenlrPtelQlriaHpveidvlpwpelRdrllrafqeeeidedeffrdvvs..............tlivWsieeeeletaeissaelsagdvtd 98 
                   +++p++l+Pt+lQ +i+H+ ++d++p p+ Rd++l a     +dede+  d +               ++ivWs                    ++d
  EEA19245.1 172 LPDQIPPTLWPTKLQQTIPHEDWVDIIPHPRWRDNVLLALGT--FDEDELWSDTIGglfegfpqseierrGVIVWS-------------------PPWD 249
                 45679*********************************7777..**********9966666666666677777774...................59** PP

     DUF3425  99 legWelkesFfrkYpylvdgl 119
                 + gWe++e F++k+  l++g+
  EEA19245.1 250 ICGWEITEGFWKKWGFLMKGC 270
                 *******************95 PP

>> HTH_15  Helix-turn-helix domain of alkylmercury lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.1   3.3e-05       0.3       9      38 ..      85     114 ..      79     117 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 3.3e-05
      HTH_15   9 slakgeeggssaellrpLlrlLakGepVtv 38 
                 sl+ +e+   +  l  pLl lLa+G+ Vt 
  EEA19245.1  85 SLPASEVDSRMGILCKPLLLLLADGKTVTP 114
                 6888999999999***************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (293 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       363  (0.0202465); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.23s 00:00:00.65 Elapsed: 00:00:00.37
# Mc/sec: 2360.38
//
Query:       EEA19246.1  [L=191]
Description: NADPH-dependent FMN reductase Lot6, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.6e-25   88.9   0.0    3.4e-25   88.6   0.0    1.1  1  FMN_red       NADPH-dependent FMN reductase
    9.5e-05   22.2   0.1    0.00016   21.4   0.1    1.3  1  Flavodoxin_2  Flavodoxin-like fold
  ------ inclusion threshold ------
      0.043   13.6   0.1      0.079   12.7   0.1    1.4  1  Rz1           Lipoprotein Rz1 precursor
      0.055   12.3   0.0        0.5    9.1   0.0    1.9  2  EP400_N       E1A-binding protein p400, N-terminal


Domain annotation for each model (and alignments):
>> FMN_red  NADPH-dependent FMN reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.6   0.0   7.6e-29   3.4e-25       2     149 ..       7     153 ..       6     157 .. 0.94

  Alignments for each domain:
  == domain 1  score: 88.6 bits;  conditional E-value: 7.6e-29
                 EEEEEES--STT-HHHHHHHHHHCCT-T...T-CEEEEETTTS.--..---HCHGHT......CGGSHHHHHHHHHHHH-SCEEEEEEECTTCE-HHHH CS
     FMN_red   2 kilvisGSlrkgsntrklaewaaealkea..gaevelidladlilpcalcdkdlese......gqtsddvaellekiaaadaliivtPeYngsysgllK 92 
                 +i +i+  +r+++++ k+ae+++++l+e   ++++ +idla  +lp  ++++    +       +t++++++ +  ia+  a+i+vtP+Yn+ y + lK
  EEA19246.1   7 RIGIIVDRHREPRTGLKVAEFVQNTLQEIshEVDLNIIDLAVWNLP--FYNEPAFPSyiysptDYTHEHTRRRSIEIASYQAFIFVTPQYNWVYLASLK 103
                 899***********************887889999***********..9997776668999999*********************************** PP

                 HHHHCHT-.SSCHCCTT-EEEEEEE-SSTTTTHHHHHHHHHHHHHTT-EEEECSEEE CS
     FMN_red  93 nalDrlsrtrgkkelrgKpvalvavgggrrgglraeeqlrqvlaelgaivvpraava 149
                 na+D+l      +el+gKp++++++gg  rgg +a+eql+qv++ l++ +++++a++
  EEA19246.1 104 NAIDYL-----FNELKGKPAMIISYGG--RGGGKAAEQLKQVCHGLRMLPLQNPAWL 153
                 ******.....7*************96..7*******************99998775 PP

>> Flavodoxin_2  Flavodoxin-like fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.1   3.7e-08   0.00016       5     108 ..      11     114 ..       8     141 .. 0.77

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 3.7e-08
                   EEE--TTGGCCHHHCHHHHHHHHHCCCTTTEEEE..EEHHCCT-----CCCCHCC.HHHHTTC.HHHHHHHHHHHHCSSEEEEEEE-BTTB--HHHH CS
  Flavodoxin_2   5 iinahprpeksfssalaqafvealekagphevtv..rdLyadflpvlttrdlaak.layeekp.adveseqiekllaadaivlqfPlwwfgvPailK 97 
                   i++ h +p   +  ++a+ + ++l++ + hev+   +dL+   lp+ ++  +    +++ + +   +++    ++++ +a ++++P +++ + a lK
    EEA19246.1  11 IVDRHREP--RTGLKVAEFVQNTLQEIS-HEVDLniIDLAVWNLPFYNEPAFPSYiYSPTDYThEHTRRRS-IEIASYQAFIFVTPQYNWVYLASLK 103
                   67778888..77789*************.66654339999889*********9855555554335666666.89*********************** PP

                   HHHHHHS-TTT CS
  Flavodoxin_2  98 gwiDrvltagf 108
                   + iD+ ++  +
    EEA19246.1 104 NAIDYLFNELK 114
                   *****987655 PP

>> Rz1  Lipoprotein Rz1 precursor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.1   1.8e-05     0.079      13      36 ..     146     169 ..     137     171 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 1.8e-05
         Rz1  13 PPaPPAWamqpppdwqqlLneiis 36 
                 P+  PAW m p  d qq   e is
  EEA19246.1 146 PLQNPAWLMFPDNDFQQRFSELIS 169
                 8889*************9998887 PP

>> EP400_N  E1A-binding protein p400, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.0   0.00011       0.5      61     127 ..       9      83 ..       2      93 .. 0.68
   2 ?    1.1   0.0      0.03   1.4e+02      93     127 ..     142     176 ..     127     188 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00011
     EP400_N  61 qiims..rspvtGqnvni....tlqnvGqvvagnq.qitltplpl.qnpaspgfqfsaqqrrfehgsssyiqvts 127
                  ii++  r p tG  v      tlq++ + v  n  ++++  lp+ ++pa p++ +s++++  eh+    i+++s
  EEA19246.1   9 GIIVDrhREPRTGLKVAEfvqnTLQEISHEVDLNIiDLAVWNLPFyNEPAFPSYIYSPTDYTHEHTRRRSIEIAS 83 
                 566541167899987765011155555555544421445557887346******************999998887 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.03
     EP400_N  93 ltplplqnpaspgfqfsaqqrrfehgsssyiqvts 127
                 l  lplqnpa   f     q+rf    s   +v+s
  EEA19246.1 142 LRMLPLQNPAWLMFPDNDFQQRFSELISKMFEVAS 176
                 788************99999999887777777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (191 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       442  (0.0246528); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1273.85
//
Query:       EEA19247.1  [L=848]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.6e-19   69.3   2.4    4.6e-19   68.5   2.4    1.4  1  Fungal_trans  Fungal specific transcription factor domain
    1.3e-09   38.0   9.2    2.8e-09   37.0   9.2    1.5  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
       0.02   14.5   0.0      0.036   13.7   0.0    1.3  1  DUF1280       Protein of unknown function (DUF1280)


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.5   2.4   7.7e-23   4.6e-19       1     266 [.     285     566 ..     285     567 .. 0.89

  Alignments for each domain:
  == domain 1  score: 68.5 bits;  conditional E-value: 7.7e-23
  Fungal_trans   1 ldrffsnfhpqfpilhkpsflpkt....ssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeili.hedfsspssslw 92 
                   l+++f+ +h++fpi+  + fl+++      ++s+   ++  + +++ila+G++ ++  + +  +  +++      f+ ra+ l  +e++  +  +l+
    EEA19247.1 285 LHSYFKSVHSLFPIVRTDLFLEQYksiwGVSGSPRPGQKWLAIFNMILAIGCRRLQFLQERLPTGVSHDL-----FFSRARCLCvNENMIFEHADLQ 376
                   689**********************9765555555666666666*****************988888766.....7779988889************ PP

  Fungal_trans  93 ilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrpp.l.lddsqinlpLPc 187
                    +q   l+ ly + s  ++ +++++g+avr a  l  + +  +        l++  +e+r Rlww++++l+  ++ ++Grp+ +    +++++p+P 
    EEA19247.1 377 QVQVEALVTLYFMVSMQINRAWKVSGIAVRSAMALAINLRITDTD------LQPGSKEARSRLWWSIYMLENVLSHMTGRPTcIgSLSFSVDQPIPY 467
                   *******************************************99......99999**************************863457899*****9 PP

  Fungal_trans 188 ddddlwesddaseetlvetk........................lsneeksrkiasfllaLkkilskiagsllsiekqlqqrdlqseklswveeler 260
                   ++d + +   ++  t+  t                          + e+++ + ++ l++L++i++   g+l+s++ +   r+     ++ ++  ++
    EEA19247.1 468 SEDMFAQPQVMDLLTNE-TLrkerlkwsldeqendkddydpfwlKDIETNQGLQFYHLVDLMHIVHITIGELFSPKGFQASRSYI---KRRIRFYDE 560
                   99955555555555554.456999*******************99999*********************************9999...999999999 PP

  Fungal_trans 261 aldnWr 266
                   +ld W 
    EEA19247.1 561 RLDHWL 566
                   999995 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.0   9.2   4.6e-13   2.8e-09       1      37 [.      83     118 ..      83     121 .. 0.90

  Alignments for each domain:
  == domain 1  score: 37.0 bits;  conditional E-value: 4.6e-13
                 SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCC CS
     Zn_clus   1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfysess 37 
                 haC+ Cr++++KCd+ +P+C+ C   +++C+ y + +
  EEA19247.1  83 HACEACRRRRIKCDGARPVCQGCHVAGTQCV-YADHK 118
                 8******************************.55544 PP

>> DUF1280  Protein of unknown function (DUF1280)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0     6e-06     0.036       5      66 ..     118     177 ..     115     182 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 6e-06
     DUF1280   5 kkkRcekvleaiqeivgeedvdeFlkdfvkflakseefkfklkLspeetfvlkvklkLsdsq 66 
                 k+ R ++ ++++++++   +++++l+d+++ + +s   ++k+ L+p +++ lk++ ++s s+
  EEA19247.1 118 KRVRDRQEMKSLKTTID--QYEHLLRDLLHEVPASAAKRIKTTLTPSDSYALKHNPSMSSSS 177
                 66677788899999955..9***********************************9999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (848 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       784  (0.043728); expected 358.6 (0.02)
Passed bias filter:                      601  (0.0335211); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.73u 0.33s 00:00:01.06 Elapsed: 00:00:00.47
# Mc/sec: 5433.95
//
Query:       EEA19248.1  [L=939]
Description: acid phosphatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.5e-31  109.9   3.7    1.4e-30  106.7   3.6    2.0  1  Phosphoesterase  Phosphoesterase family
      3e-19   69.1   4.7    8.9e-19   67.6   4.7    1.9  1  MBOAT_2          Membrane bound O-acyl transferase family
     0.0088   15.5   0.0      0.015   14.7   0.0    1.3  1  Sulfatase        Sulfatase


Domain annotation for each model (and alignments):
>> Phosphoesterase  Phosphoesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.7   3.6   2.4e-34   1.4e-30     110     356 .]      79     302 ..      70     302 .. 0.89

  Alignments for each domain:
  == domain 1  score: 106.7 bits;  conditional E-value: 2.4e-34
  Phosphoesterase 110 lwelaqeftlcDryFssvlggtepNrlflisgtsdpsGteggpsladpkktvlkgftqktigerLsekgvswaiYqealdnlakskva.....p 198
                      l el ++    ++y+ +v++++epN+++   g       +g ++    ++    + +++ti +  ++  +sw+ Yqe l ++a+++       +
       EEA19248.1  79 LDELKKNGIFLNNYW-AVTHPSEPNYIAAAGGDH-----FGMDN----DNFWQIPNNVATIADLFDTRKISWGEYQEGL-PYAGYQGFrypesG 161
                      567777777788887.******************.....99977....899999*************************.77777766666889 PP

  Phosphoesterase 199 fnyyvrklkklearrkalkqlglaakq..lekfkkdvkngkLPqvsfikpngandeHpgadvaagdklikevlealtsspq.waktllivtyDE 289
                       n+yvrk+++l  +++   +++  +++  + +f +d++n++LPq+sfi+pn++nd+H++ +va+   +  ++l+ l ++++ +++tl+++t+DE
       EEA19248.1 162 PNNYVRKHNPLVIFNSVTDDATRLRQIknFTSFYDDLDNESLPQYSFITPNMTNDGHDT-NVAFSGTWSYNFLADLLKNEYfMKDTLVMLTFDE 254
                      99**********99999999999888789******************************.********************************** PP

  Phosphoesterase 290 ngGfyDhVappvapvsdpdglkGdpyglgvrvPllviSpyakk...gtvdhelfdhtSvlrfiekrfglp 356
                       g +    + p                  + v +l+++  +     gt d++++ h+Sv++ ++++++lp
       EEA19248.1 255 GGNY----THP------------------NSVYTLLVGGAIPDhlkGTTDSTFYTHYSVIASLSANWELP 302
                      *998....334..................67888888844433555*********************996 PP

>> MBOAT_2  Membrane bound O-acyl transferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.6   4.7   1.5e-22   8.9e-19       1      83 []     779     867 ..     779     867 .. 0.93

  Alignments for each domain:
  == domain 1  score: 67.6 bits;  conditional E-value: 1.5e-22
     MBOAT_2   1 wpplfgslleayslrrfWgrfWHqlfrrglkstakkilrlllg....sklarylqllvaFllSGllHaagdytqlap..estallfFll 83 
                 wpp+fgsl++a+s+r+fWg+fWH+++ r++++++  ++r++l+    s +++ + +lv++l+SG++H ++++  + +  +s  +++F++
  EEA19248.1 779 WPPIFGSLSNASSMRNFWGKFWHRILVRPYENYSCLFCRNILQlkpgSVWDKTMFVLVIYLISGIVHSFVSWNYGDKcgWSSDIWWFCC 867
                 9*****************************************9766666***************************8777779999985 PP

>> Sulfatase  Sulfatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   2.5e-06     0.015      27     111 ..      77     145 ..      62     229 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 2.5e-06
                 HHHHHHHHTSEEESSEE-SSSSHHHHHHHHHHSS-HHHHTHSSCCSTTTHHCTTTS-HHHHHHHHTT-EEEEEEES-SCCSGGGS CS
   Sulfatase  27 pnldrlaeeglrftnfysaaplcspsraalltgryphnsgvasntevgggglpqteatLpellkeaGYntaaigkwhlgwssrqs 111
                 p+ld+l ++g+ ++n++ a  ++ ps+++       +++g+  n ++  +++p+++at+++l+  +            +w + q 
  EEA19248.1  77 PHLDELKKNGIFLNNYW-A--VTHPSEPNYIAAAGGDHFGMD-NDNF--WQIPNNVATIADLFDTRKI----------SWGEYQE 145
                 9***************8.4..8******************63.3333..**************98843..........4444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (939 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       436  (0.0243181); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.67u 0.26s 00:00:00.93 Elapsed: 00:00:00.43
# Mc/sec: 6597.90
//
Query:       EEA19249.1  [L=374]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (374 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       633  (0.0353059); expected 358.6 (0.02)
Passed bias filter:                      344  (0.0191868); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2692.80
//
Query:       EEA19250.1  [L=509]
Description: vitamin B6 transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.5e-19   68.0  39.0    6.4e-18   64.8  38.9    2.4  1  Transp_cyt_pur  Permease for cytosine/purines, uracil, thiami
  ------ inclusion threshold ------
        1.1    8.8   2.1        1.8    8.1   2.1    1.3  1  Fzo_mitofusin   fzo-like conserved region


Domain annotation for each model (and alignments):
>> Transp_cyt_pur  Permease for cytosine/purines, uracil, thiamine, allantoin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.8  38.9   7.1e-22   6.4e-18       2     419 ..      54     465 ..      53     488 .. 0.75

  Alignments for each domain:
  == domain 1  score: 64.8 bits;  conditional E-value: 7.1e-22
  Transp_cyt_pur   2 vpeeeRtwkt....lnlfsiWlganlnintwvigalg.lalgLnwwqsvlviivgnligaifvallglaGakyGlpfpilsRasfGirgsllpll 91 
                     vpe+eR++ +    ++++ +W+++n+  n++++g lg l +gL++ +s l+  +g+l+ga+  a +g  G+  G ++++++R+  G + s + +l
      EEA19250.1  54 VPESERHSVAaadyMQMALLWFSTNITANNIAVGMLGpLDYGLSFTDSALCATFGALLGAAGAAYMGTWGPVSGNRTMVIARYFMGYYPSKICAL 148
                     89999987653222788999*************************************************************************** PP

  Transp_cyt_pur  92 lrvviaivwfgvqawiGsealllmlgkifgkwleiggailgtsltelvtffifwvvslvivllgvskirkffviaallvpvaafgfliwalvkae 186
                     l +vi +++  + + +G+++l+ + g  +   + +g +i+ + +t +v +f+ +v ++++ +++v+++ ++fv+   + p    +f+  + +  +
      EEA19250.1 149 LNIVIMLGYGMIDCLVGGQVLSAVAGGNMT--IVVG-TIIVAIITWIVVVFGMSVFHKYERWAWVPQLIALFVLVGSAGP----KFDTNIPSVGT 236
                     ***********************9988765..6666.9999999999*********************999986554444....44444444333 PP

  Transp_cyt_pur 187 gGpvldkavklgkselflsavagvlagfatlilnapDFtryaktkkssvkiqlvavpllftlllligilvaaaakaayganawspl.d......i 274
                       +++ +   l+    f     ++l++ +++++  +D+ +y ++++++  ++++++++    l+++ +l++ +++ ++   +w++  d      i
      EEA19250.1 237 SRDIAGNR--LS----FF---SLCLSSSVAWAPAGADYYVYYPPTTKKWATFTMSFFGIGLALTFANLLGVGLGSGTFSNADWAAAnDvssgalI 322
                     32222222..22....33...355555555555556********************999999999999988777666555555443032222226 PP

  Transp_cyt_pur 275 lakfdetagvllililvala.qlgvnisanllsagldlaallPkkinikrgsliaavialvivpwkllsssskl...ftaflsllavflspvagv 365
                     ++ +d + g++   + v++a +l  n+   ++sa l +++l  + +++ r    +  + + ++ +  l+  + l   f +fl l+++ ++ + ++
      EEA19250.1 323 MQGYDGL-GGFGKFLGVLIAlGLIANNIPGTYSATLGFQTLGRYGVALPRWFWTCVGVIIYTACA--LGGRDHLfeiFENFLALMGYWVTIFLVI 414
                     6777777.7777666666653678888999*************9999999887777776666666..4444544478999**************9 PP

  Transp_cyt_pur 366 iiadyfvvrrgylklaalytrrrgsaYwy...rkgvNwravaayivGiaaglvgvag 419
                     ++ +  + r g+++ a   +       w    +    ++a+ a+++G + +++ +  
      EEA19250.1 415 VLEEHMIFRWGKIAPAFDWS------LWAdrsKLPLGLAAFTAFVIGWIGSIMCMYQ 465
                     99999999988887665555......2222112234566666666666666666554 PP

>> Fzo_mitofusin  fzo-like conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   2.1    0.0002       1.8      20      59 ..     174     209 ..     161     212 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0002
  Fzo_mitofusin  20 rtslgvlvvggvvlravgWrvialslalygllYlyErltw 59 
                     + + ++vvg++++  + W v+++ ++++     yEr++w
     EEA19250.1 174 GGNM-TIVVGTIIVAIITWIVVVFGMSVF---HKYERWAW 209
                    4444.5899**************999865...78*****9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (509 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       895  (0.0499191); expected 358.6 (0.02)
Passed bias filter:                      389  (0.0216967); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 3407.41
//
Query:       EEA19251.1  [L=257]
Description: prolyl 4-hydroxylase alpha subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.3e-10   40.1   0.1      1e-09   39.2   0.0    1.5  2  2OG-FeII_Oxy_3  2OG-Fe(II) oxygenase superfamily


Domain annotation for each model (and alignments):
>> 2OG-FeII_Oxy_3  2OG-Fe(II) oxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0         1   1.8e+04      13      20 ..      93     100 ..      90     118 .. 0.63
   2 !   39.2   0.0   5.7e-14     1e-09       3      96 .]     139     254 ..     137     254 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 1
                     EEE-SS-- CS
  2OG-FeII_Oxy_3  13 kpHvDnfe 20 
                     kpH+D+ +
      EEA19251.1  93 KPHIDKAY 100
                     58888654 PP

  == domain 2  score: 39.2 bits;  conditional E-value: 5.7e-14
                     EEEE-TT-EEEEE-SS--..--TT.-.EEEEEEEEE....ET-B--EEE...........................---TT-EEEEE-..B-T.. CS
  2OG-FeII_Oxy_3   3 vlrygegqeykpHvDnfe..keegsgqrrltvllyLnekeseeGGelelyekdk.................eavkikpkkgrlvlFesdellp.. 76 
                     v++yg +++y+ H+D+f+  ++ g g+   t+++y +  ++ +GG   + + ++                 e v++kp  g+++++e+  l++  
      EEA19251.1 139 VQNYGISGQYRDHYDWFDdaHAVG-GNIASTFFVYIQ--ANCTGGGTNFARLTPpddeswcefidcdrpfdEGVTFKPILGNAIYWEN--LHDdd 228
                     789999899*********955555.99999******5..788888844433333455777777777779999999*************..76678 PP

                     .......EEE--B.-SS-EEEEEEEEE CS
  2OG-FeII_Oxy_3  77 .......HevlpvtkggeRlsltgwir 96 
                            H+++pvt+g +++ +++w +
      EEA19251.1 229 aghkmtlHAGMPVTTG-NKMGMNMWTW 254
                     *************886.********75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (257 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       438  (0.0244297); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1669.12
//
Query:       EEA19252.1  [L=342]
Description: protein disulfide isomerase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.3e-17   63.5   0.0    3.5e-17   62.9   0.0    1.4  1  Thioredoxin_6  Thioredoxin-like domain
      4e-09   36.4   0.0    2.3e-06   27.5   0.0    2.4  2  Thioredoxin    Thioredoxin
  ------ inclusion threshold ------
       0.11   12.6   0.0        6.2    6.9   0.0    2.3  2  DUF727         Protein of unknown function (DUF727)


Domain annotation for each model (and alignments):
>> Thioredoxin_6  Thioredoxin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.9   0.0   5.9e-21   3.5e-17      18     183 ..     167     324 ..     124     325 .. 0.89

  Alignments for each domain:
  == domain 1  score: 62.9 bits;  conditional E-value: 5.9e-21
                    T-T.TSEEEEE--HHHHHHTT--SSEEEEEETTTTEEEEEETHT--HHHHHHHHHHH---SEEE-SHHHHHHHHTSS--EEEEEEE-TTSTTHHHH CS
  Thioredoxin_6  18 elkgdvrfgvtkskevadklgvkepavllfrkfdeekvkydgekitvddlkkfieknslplvreltpenaeelfeeglppllllflkkddeetekl 113
                    el +d+ +gv +++  ++k   k++ +++++  de + kydg  +++d + +f    s pl+r+++  ++  ++++glp  +  ++   d+e + l
     EEA19252.1 167 ELAKDFFVGVMSDTQ-SEK---KNSFITVYNVRDETTPKYDGP-FEKDAILHFAGLVSQPLIRQFDMSSLVSFMKSGLP--IGMIYSAKDDERQSL 255
                    666778888776433.222...33567788888899999***6.*********************************99..44444446889**** PP

                    HHHHHHHHHHTTTT-EEEEEETTGGHHHHHHTT--GGG-SEEEEEESSSS-EEEETTSS--HHHHHHHHH CS
  Thioredoxin_6 114 kkaiekvakefkdkinfaladaksfkrpleylglsssdlPvivivdsashkykyppkdefspeklkeFlk 183
                     +a++ va  +++k+nfa++da ++   le +gl++++lP++v ++  ++ yk+ p   ++p+++++Flk
     EEA19252.1 256 AAALSDVAMGYRGKVNFATVDAIKNSFALEPMGLNTDELPAFV-IQINDKIYKFGPGLTITPKAIDAFLK 324
                    *******************************************.8889999***99************98 PP

>> Thioredoxin  Thioredoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.5   0.0   3.8e-10   2.3e-06      32     100 ..      48     117 ..      46     120 .. 0.91
   2 !    6.5   0.0    0.0014       8.4      34      83 ..     253     304 ..     251     324 .. 0.79

  Alignments for each domain:
  == domain 1  score: 27.5 bits;  conditional E-value: 3.8e-10
                  HHHCHHHHHHHHHHHCTT..TSEEEEEETTTSHHHHHHTT-SSSSEEEEEETTEEEEEEESS-HHHHHHHH CS
  Thioredoxin  32 hCkalaPeleklaeelkd..kvklakvdvdenedlakkyevegiPtlklfkngkevkkyegarekeklaaf 100
                  +Ckal  el  +ae l++  +v ++++d+ e+e+ ++ ++v ++Pt++ f++ k  ++y g + ++ l+++
   EEA19252.1  48 KCKALHNELVLAAESLSKssDVSIYEIDCLEHEKFCASLDVLSFPTIRTFEHQK-WSRYRGPQRATPLVTH 117
                  6****************99*****************************999876.8899999888877765 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0014
                  HCHHHHHHHHHHHCTTTSEEEEEETTTSHHHHHH..TT-SSSSEEEEEETTE CS
  Thioredoxin  34 kalaPeleklaeelkdkvklakvdvdenedlakk..yevegiPtlklfkngk 83 
                  ++la  l ++a  +++kv +a vd+ +n+   +   ++ + +P++++  n+k
   EEA19252.1 253 QSLAAALSDVAMGYRGKVNFATVDAIKNSFALEPmgLNTDELPAFVIQINDK 304
                  67999999*******************9866554114556788887766655 PP

>> DUF727  Protein of unknown function (DUF727)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.0     0.001       6.2      12      48 ..      49      86 ..      40     103 .. 0.81
   2 ?    3.2   0.0     0.015        89      66      97 ..     178     209 ..     162     217 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.001
      DUF727 12 vafgVkeisv.seklpsteeviylnvetlEgeelcvel 48
                +++  +e+++ +e+l+++++v + ++ +lE+e++c  l
  EEA19252.1 49 CKALHNELVLaAESLSKSSDVSIYEIDCLEHEKFCASL 86
                555556664449***********************877 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.015
      DUF727  66 eeekedeekyfetlyaLLdkiSpeyrekFgek 97 
                 ++ +++++++f t+y++ d+  p+y   F++ 
  EEA19252.1 178 SDTQSEKKNSFITVYNVRDETTPKYDGPFEKD 209
                 4566778899***************9999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       333  (0.0185733); expected 358.6 (0.02)
Passed bias filter:                      318  (0.0177366); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 2336.42
//
Query:       EEA19253.1  [L=283]
Description: hypothetical protein PMAA_015110 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (283 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       390  (0.0217525); expected 358.6 (0.02)
Passed bias filter:                      375  (0.0209158); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 1871.16
//
Query:       EEA19254.1  [L=444]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.5e-26   91.8   0.0    5.9e-26   91.1   0.0    1.2  1  Transferase  Transferase family
  ------ inclusion threshold ------
      0.054   13.6   0.0       0.53   10.4   0.0    2.4  3  DUF3475      Domain of unknown function (DUF3475)


Domain annotation for each model (and alignments):
>> Transferase  Transferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.1   0.0   6.5e-30   5.9e-26      22     423 ..       7     431 ..       3     437 .. 0.82

  Alignments for each domain:
  == domain 1  score: 91.1 bits;  conditional E-value: 6.5e-30
  Transferase  22 LkLSilDlllpevivkacyfykknkelsqen.vsekLktsLsetLtkfypLAGrLktsesgrlelsCndeG......adFveAeadveLsdlkkle.. 110
                   +LS lD   p++ivk c+ ++k +e  +     e L++ L   + + +++AG + +++sg++ ++    G      ++  + +     +dl ++   
   EEA19254.1   7 YELSDLDRQVPDTIVK-CFTFCKLQETLELDkLKEALQQGLDSAIEHLPFMAGNICVDQSGKPYIESVP-GtrvelhVKHYTSKQHKSFTDLAQNCfh 102
                  58**************.88888877766654378888888888999*******************9653.3355566777777777779999887788 PP

  Transferase 111 .pddslenllpqlavkkegeaipllavqvTkfkcGgvalgvsvsHaiaDgaSlktfieswaelarge....kkvtvtplfarelllprpeppsv.... 199
                   +d  l+ llp+l v++    ip   +q   ++  g++l  s  H  +D +S+  f+ +    ++      + ++  ++ +r  ++++  p sv    
   EEA19254.1 103 pDDLDLAMLLPELPVDH----IPACGLQLNVIEG-GLILASSAHHFAVDFTSMRIFLGAVYMGSKAYyygyPLLNFAISLDRRPFNGQSVPESVskqe 195
                  6777899999*777764....5778888877775.5*********************9875555433444589999************7777778888 PP

  Transferase 200 ......efdqlelrkfsasettevkevvtkkivleklsaskleeLkkkasdesngkpatrfesvtallWrcavkarkldeske...tvlgiavdiRsr 288
                        e+  l+l+ + ++ ++ v+ +  + ++++ +s ++++eLk++ +  + +k +t+f+ ++a lW+++++ar ++++++   + l+  +d+Rsr
   EEA19254.1 196 lldlcpEYRVLDLKGTLNCRSNAVDLAEYQMKIYK-ISEEEIAELKEQCYLPEGVKYVTSFDCISAALWKSVTRARVSTTVEKlaySSLVFTIDLRSR 292
                  88888889999988899999999999999888888.********************************************999999************ PP

  Transferase 289 lepkl.peeyfGNallsvvv.kstakell.seelsrivekvkeavkkaitkeylsseidweens.tlkaelvskgkkdgeevtvsswlklplyevdFG 382
                   +++     yfGNa+  + + + +a+ ll  e +s +++ + ++++ +   ++  +++ + + +  ++ +l +  ++++  ++v sw +  + + dFG
   EEA19254.1 293 DPEHVtSTCYFGNAVALIQAgPLDAQSLLgGEGISIAASSIRQKINGVTISSI--KDLTQLIRClPPNEKLKYDAEFKDTDFLVNSWFSEKVEDFDFG 388
                  996551567*****987655267887766157799999*****9999544444..355666666555666778888888******************* PP

  Transferase 383 wgkPvyvvpvvsskkdnkilllpsk..eddggvevlvtLpeee 423
                   g P + +p+  +  ++  + lp      +++ e+l+ L ++e
   EEA19254.1 389 AGVPEALRPKPNPLIGAFCVFLPCFdnPSKRTYELLIQLRPKE 431
                  **********999999996666644334788899999887665 PP

>> DUF3475  Domain of unknown function (DUF3475)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.0       1.5   1.4e+04      19      31 ..     190     202 ..     187     206 .. 0.77
   2 ?   10.4   0.0   5.9e-05      0.53      20      45 ..     231     256 ..     227     259 .. 0.93
   3 ?   -0.5   0.0      0.15   1.3e+03      14      32 ..     260     278 ..     258     287 .. 0.79

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 1.5
     DUF3475  19 sLsdkevarLree 31 
                 s+s++e+  L+ e
  EEA19254.1 190 SVSKQELLDLCPE 202
                 8888888888765 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 5.9e-05
     DUF3475  20 LsdkevarLreeilrseGVrkLvSkD 45 
                 +s++e+a+L+e++   eGV++ +S D
  EEA19254.1 231 ISEEEIAELKEQCYLPEGVKYVTSFD 256
                 69*********************988 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 0.15
     DUF3475  14 vnLwqsLsdkevarLreei 32 
                 + Lw+s++++ v++  e++
  EEA19254.1 260 AALWKSVTRARVSTTVEKL 278
                 679******9998766655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (444 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       400  (0.0223102); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 2976.70
//
Query:       EEA19255.1  [L=302]
Description: NmrA-like family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-22   80.8   0.1    2.6e-22   79.6   0.1    1.5  1  NmrA             NmrA-like family
    1.6e-18   67.3   0.0    4.5e-18   65.8   0.0    1.7  2  NAD_binding_10   NAD(P)H-binding
    4.4e-07   30.2   0.1      2e-06   28.1   0.0    1.9  2  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma
    3.7e-05   24.2   0.1    0.00027   21.4   0.0    2.2  2  Semialdhyde_dh   Semialdehyde dehydrogenase, NAD binding doma
     0.0029   16.9   0.7       0.05   12.9   0.7    2.2  1  THF_DHG_CYH_C    Tetrahydrofolate dehydrogenase/cyclohydrolas
     0.0039   17.3   0.6      0.017   15.3   0.1    2.2  2  DapB_N           Dihydrodipicolinate reductase, N-terminus
     0.0051   16.3   0.0      0.039   13.4   0.0    2.1  2  Epimerase        NAD dependent epimerase/dehydratase family
     0.0092   16.0   0.0      0.017   15.2   0.0    1.4  1  Shikimate_DH     Shikimate / quinate 5-dehydrogenase
  ------ inclusion threshold ------
       0.13   11.4   0.1       0.42    9.7   0.0    1.9  3  NAD_binding_4    Male sterility protein


Domain annotation for each model (and alignments):
>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.6   0.1   1.3e-25   2.6e-22       1     225 [.       8     223 ..       8     233 .. 0.83

  Alignments for each domain:
  == domain 1  score: 79.6 bits;  conditional E-value: 1.3e-25
                 EEESSTTSHHHHHHHHHHHH.HT-EEEEEES-S-SHHHHHHHHSTTEEE.ES-TT-HHHHHHHHTT-SEEEE---GGS-HHHHHHHHHHHHHHHS-SEE CS
        NmrA   1 IlviGaTGrqGksvvrallk.aghkvralvRdtkselakslkeaGvelv.kgdlddkeslvealkgvdvvfsvtgfyskeiedgkklvdAakeaGvkhf 97 
                 ++ iGa+G  G+ + +all+  + +v ++ R+t+  +       + + v   d  +++ l++a+ g d+v+s++g   +   ++kk +dAa++aGvk+f
  EEA19255.1   8 VVLIGASGTVGQIILQALLAcPDINVTVVSRNTSDATFP-----PEVSVrRIDF-SESELSSAFTGQDAVISAVG--ATAFTEQKKFIDAAVHAGVKRF 98 
                 678*****************99***********987653.....3444435555.45669***************..********************** PP

                 EEEE---GG.GT.SSS---TTTHHHHHHHHHHHHC...TS-EEEEEE-EEGGG-BSSS-SS-BEEE-TTS.-EEEEESS-TTS-EE-HHHHHHHHHHHH CS
        NmrA  98 iySslgddndrsnaeepavphfdsKaeieeyvral...gipytfvyagffmenflsllaqlkvgdtappedkvtllgpgnpkavlldaeeDiGafviki 193
                 i+S++ ++    + +   vp+f++K  i +y+++    g+  t +++ +     l++       d+++   ++++   g+ k + l++e++ G+ v+++
  EEA19255.1  99 IPSEFSSNTP-NESVLRMVPLFNQKKDILDYLQSKesvGLTWTGIATSLLFDWGLTSGFL--GYDLSKR--TAIIWDGGD-KRFTLINERELGQCVVSV 191
                 ******9995.4577889**************988888***9999988777776664333..2444444..344444455.556667************ PP

                 HHHHHHHTTEEEEE-SEEE-HHHHHHHHHHHH CS
        NmrA 194 lkdprklkgkriklagntlsgneivelfekki 225
                 lk+p+++ +k++ +++ ++s +ei++ +e ++
  EEA19255.1 192 LKHPQETINKYLYISSVEVSQQEILQTLEAVT 223
                 **************************999886 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.8   0.0   2.3e-21   4.5e-18       1     153 [.      12     155 ..      12     195 .. 0.74
   2 ?   -0.5   0.0      0.48   9.6e+02      88     112 ..     197     222 ..     163     296 .. 0.59

  Alignments for each domain:
  == domain 1  score: 65.8 bits;  conditional E-value: 2.3e-21
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHHCTTTCEEEE--TT-CCHHHHHHTT-SEEEES---TCCHHHHHHHHHHHHHHCT--EEEE CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpeklaeleaeeglevvegdvtdvedlaealkgadaVvsalggggkdeegaknivdaakeagvkRfvl 95 
                     GA+G vG+ +++ lla  +++vt++ Rn+++++ ++  ++++v  +d++ +++l +a++g+daV+sa+g+++   +  k+ +daa  agvkRf+ 
      EEA19255.1  12 GASGTVGQIILQALLACPDINVTVVSRNTSDAT-FP--PEVSVRRIDFS-ESELSSAFTGQDAVISAVGATAF--TEQKKFIDAAVHAGVKRFIP 100
                     9*******************************9.76..9*********8.889****************9886..679****************9 PP

                     EEETTTTSGCGCHHHHHHHHCCHHHHHHHHHHHHHHHH..S.SSEEEEEEE-CEE-ST.--S CS
  NAD_binding_10  96 vsaigvgdevpgefgewnkellkaylaakraaeellra..s.gldwTivrpggLtdep.ttk 153
                           +   p+e  ++ +  + + +  k+   ++l++  s gl+wT +  + L d   t++
      EEA19255.1 101 SEFSSNT---PNE--SVLR--MVPLFNQKKDILDYLQSkeSvGLTWTGIATSLLFDWGlTSG 155
                     6665444...222..2222..3467788888888887755369********99999874443 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.48
                     CT--EEEEEEETTTTS.GCGCHHHHH CS
  NAD_binding_10  88 agvkRfvlvsaigvgd.evpgefgew 112
                     + +++++++s++ v + e+ ++++ +
      EEA19255.1 197 ETINKYLYISSVEVSQqEILQTLEAV 222
                     45666666666666542222333322 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.1   0.0   9.9e-10     2e-06       1      94 [.       8      95 ..       8     112 .. 0.90
   2 ?   -0.7   0.0      0.79   1.6e+03      49      83 ..     205     239 ..     184     250 .. 0.62

  Alignments for each domain:
  == domain 1  score: 28.1 bits;  conditional E-value: 9.9e-10
                     EEEE--.SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHHHTTSSEEEE-SSGG...GHHHHHHHHHHH CS
  Sacchrp_dh_NADP  1 vliiGa.GsvGqavaellarhfdvdaeitvadrskeklealaakalgvrfeaialdaenyeavLaallkegdlvvnlsppi...ssldvlkaCiet 92
                     v++iGa G vGq +++ l++  d+  ++tv++r+ +   a+      ++++ + +d ++ e  L+++ +++d+v+++++ +   +  + ++a++ +
       EEA19255.1  8 VVLIGAsGTVGQIILQALLACPDI--NVTVVSRNTSD--AT----FPPEVSVRRIDFSESE--LSSAFTGQDAVISAVGATaftEQKKFIDAAVHA 93
                     79**********************..***********..55....4789999999988766..8***************99877888999999999 PP

                     T- CS
  Sacchrp_dh_NADP 93 gv 94
                     gv
       EEA19255.1 94 GV 95
                     98 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.79
                      EEEEE--TTTHHHHHHHHHTTSSEEEE-SSGGGHH CS
  Sacchrp_dh_NADP  49 feaialdaenyeavLaallkegdlvvnlsppissl 83 
                      ++++++  +++ ++L+a+ +++  v+n + + ++ 
       EEA19255.1 205 ISSVEVSQQEILQTLEAVTASKWKVINTTSDAQTT 239
                      45566666666666666666666666666655544 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0   1.4e-07   0.00027       1      91 [.       7      95 ..       7     106 .. 0.74
   2 ?    0.2   0.0      0.47   9.5e+02      81     101 ..     217     237 ..     181     273 .. 0.80

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 1.4e-07
                    EEEEETTTSHHHHHHHHHHHCTSSEEEEEEEESTTTTTSBHHHHSGGGTTTECEBEEE.GGGGGCTT-SEEEE-SCHHH...HHHHHHHHHHTTS CS
  Semialdhyde_dh  1 kvaivGatGyvGqellrlLeehpevelvvllsssrsaGkklaeavkaleegkdlkved.vdeeelkevdivflalpagv...skelapklaeagv 91
                    +v ++Ga+G vGq +l+ L   p+++++v++ +++    ++   v+    ++ + +++   + ++ + d v++a++a +    k++ +++++agv
      EEA19255.1  7 NVVLIGASGTVGQIILQALLACPDINVTVVSRNTS--DATFPPEVS----VRRIDFSEsELSSAFTGQDAVISAVGATAfteQKKFIDAAVHAGV 95
                    699************************99666555..444444434....667777774456678999999999998761114555555566665 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.47
                     HHHHHHHHTTSEEEESSSTTT CS
  Semialdhyde_dh  81 elapklaeagvkviDlssdfR 101
                     +  +++ ++++kvi  +sd  
      EEA19255.1 217 QTLEAVTASKWKVINTTSDAQ 237
                     555677888889998888875 PP

>> THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.9   0.7   2.5e-05      0.05      37      73 ..       6      43 ..       1      98 [. 0.74

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.5e-05
                   -EEEEE---TTTHHHHHHHHHC.TT-EEEEE-TTSCCH CS
  THF_DHG_CYH_C 37 kkvvvvGrsnivgkplallLle.knatVtvchsktkdl 73
                   k+vv +G+s +vg+ + + Ll+  +  Vtv+ ++t+d 
     EEA19255.1  6 KNVVLIGASGTVGQIILQALLAcPDINVTVVSRNTSDA 43
                   89************976655552577777777777654 PP

>> DapB_N  Dihydrodipicolinate reductase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.1   8.4e-06     0.017       2      73 ..       7      73 ..       6     101 .. 0.65
   2 ?   -1.0   0.0      0.88   1.8e+03      52      80 ..     210     238 ..     178     248 .. 0.53

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 8.4e-06
                EEEEETTTSHHHHHHHHHHHHSTTEEEEEEEETTCSTTTTTBHHHHSSSS--S-BEBSSHHHHHHH-SEEEE CS
      DapB_N  2 kvavvGasGrmGkevvkaveeaedlelvaavdrkeselegkdagellglgklgvavtddleevlekadvliD 73
                +v+++GasG++G+ +++a+ + +d++++ +  +++    +  +   ++++++++  +++l+++++ +d +i 
  EEA19255.1  7 NVVLIGASGTVGQIILQALLACPDINVTVVSRNTS----DATFPPEVSVRRIDFS-ESELSSAFTGQDAVIS 73
                699***********************998877766....2222233333333332.3566666666665554 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.88
                 --S-BEBSSHHHHHHH-SEEEE-S-HHHH CS
      DapB_N  52 klgvavtddleevlekadvliDFTtpeav 80 
                  ++ ++ ++le+v+++   +i  T+ + +
  EEA19255.1 210 VSQQEILQTLEAVTASKWKVINTTSDAQT 238
                 33344445666666655555555555444 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.0   1.9e-05     0.039       2      73 ..       9      76 ..       8      98 .. 0.77
   2 ?    0.5   0.0      0.17   3.4e+02     200     232 ..     166     198 ..     152     238 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 1.9e-05
                EEETTTSHHHHHHHHHHHHCT.SEEEEEES-STTTTCHHCHHCEEEE--TT-HHHHHHHHHHHT-SEEEE--S CS
   Epimerase  2 lVtGatGfiGsalvkallekg.yevigldrlssasntarledlelveldltdrsalerlfkeeqpdavihlAa 73
                +++Ga+G +G+ +++all+   ++v++++r++s+  +  +  +++ ++d+ +++ l  +f   + davi + +
  EEA19255.1  9 VLIGASGTVGQIILQALLACPdINVTVVSRNTSDATFPPE--VSVRRIDFSESE-LSSAFT--GQDAVISAVG 76
                789****************99899*******888877654..589999999766.666677..6799999833 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.17
                 EEEETTST-EEEEEEHHHHHHHHHHHHHHHTT- CS
   Epimerase 200 vtllgdgtalRdflyveDvaeaillvlehvdag 232
                  ++++ g+ +  ++  +++ ++++ vl+h+++ 
  EEA19255.1 166 AIIWDGGDKRFTLINERELGQCVVSVLKHPQET 198
                 568888888888888888888888888887663 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   8.4e-06     0.017      13      99 ..       6      91 ..       2      99 .. 0.82

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 8.4e-06
                  -EEEEES-.SHHHHHHHHHHHCCT-CEEEEEESSHHHHHHHHHHHT.ET-EEEEGCGHHHHHHT-SEEEE-SSSSS-SB-HHHHHCCH CS
  Shikimate_DH 13 kkvlliGa.GemaelvakhLlakgvkkvvvaNRtlerakelaeelkgeeiealkleelkellaeadvvisataseepilekeeveeal 99
                  k+v+liGa G +++ ++++Lla    +v+v+ R+ + a  +  e++  +    + +el+++    d visa++++ +  +k+ + +a+
    EEA19255.1  6 KNVVLIGAsGTVGQIILQALLACPDINVTVVSRNTSDAT-FPPEVSVRR-IDFSESELSSAFTGQDAVISAVGATAFTEQKKFIDAAV 91
                  79*****98*************98888*******99885.677775553.44555899****************98877777666655 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.0   0.00021      0.42       2      35 ..      11      43 ..      10      68 .. 0.87
   2 ?   -3.1   0.0       1.7   3.4e+03     130     157 ..     201     228 ..     192     248 .. 0.60
   3 ?   -2.8   0.0       1.4   2.8e+03      69      87 ..     278     296 ..     272     297 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00021
                   E-TTSHHHHHHHHHHHHHS-.TEEEEEE-SSSHH CS
  NAD_binding_4  2 TGaTGFLGkvLlekLLrttpevkiyllvRaksge 35
                    Ga+G +G+++l+ LL +  +++++++ R++s++
     EEA19255.1 11 IGASGTVGQIILQALLACP-DINVTVVSRNTSDA 43
                   6***************986.69*****9998875 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 1.7
                    -EEEEEE.GGGTTS-TTT--SSS-H.... CS
  NAD_binding_4 130 vllhvST.ayvngeregeveekvyeegek 157
                     +l++S+  ++++e  ++  e v+ +++k
     EEA19255.1 201 KYLYISSvEVSQQEILQT-LEAVTASKWK 228
                    567788866666666644.4555554543 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 1.4
                    TTSGGGG--HHHHHHHHHH CS
  NAD_binding_4  69 lseprlGLseedlqelaee 87 
                    l+++ lGL++e++++ +++
     EEA19255.1 278 LANDLLGLKPESVKQTIKR 296
                    77888******99998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (302 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       594  (0.0331307); expected 358.6 (0.02)
Passed bias filter:                      504  (0.0281109); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.45
# Mc/sec: 2001.57
//
Query:       EEA19256.1  [L=463]
Description: fungal specific transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.5e-12   46.4   0.0    3.8e-12   45.8   0.0    1.5  1  Fungal_trans    Fungal specific transcription factor domain
     0.0089   15.6   0.6       0.02   14.5   0.6    1.6  1  RPA_interact_N  Replication protein A interacting N-terminal


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.8   0.0   4.3e-16   3.8e-12      36     193 ..     103     253 ..      67     396 .. 0.83

  Alignments for each domain:
  == domain 1  score: 45.8 bits;  conditional E-value: 4.3e-16
  Fungal_trans  36 spllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLlllelyektssdralherhhgvavrlarslgLhrn 132
                   +++l+++i+      +++ + +++ ++++ +     + +r + +++ + + ++ +l +lq+++++        + + +  ++g+av  a +lgLhr+
    EEA19256.1 103 ENFLMFSIYYASVVVMSTSECFKEVKEERQV-LLERYRIRLDQFLSLSDFMETADLAVLQAFVIYLAIGTYDVNGPDVHSMVGLAVGRAIKLGLHRD 198
                   5666666666666666666666666666655.33334447777777778888999*****99999988888888888999***************** PP

  Fungal_trans 133 psyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddlw 193
                    +  g      ++ +e e+rrRlww +  lD+++a +++  p + +++ n+ LP + +d+ 
    EEA19256.1 199 GEGLG------VPLFETEMRRRLWWQICTLDVRTAQDHRSDPCILEHSFNTKLPANISDVS 253
                   *****......*******************************99************99875 PP

>> RPA_interact_N  Replication protein A interacting N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.6   2.2e-06      0.02      20      38 ..     122     140 ..     121     141 .. 0.93

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 2.2e-06
  RPA_interact_N  20 rCleRlresRsqLLwklRq 38 
                      C+++++e+R+ LL+++R 
      EEA19256.1 122 ECFKEVKEERQVLLERYRI 140
                     6*****************5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (463 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       459  (0.025601); expected 358.6 (0.02)
Passed bias filter:                      367  (0.0204696); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.43
# Mc/sec: 3240.82
//
Query:       EEA19257.1  [L=599]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.3e-39  133.9   1.4    1.1e-38  133.1   1.4    1.4  1  Glyco_trans_2_3  Glycosyl transferase family group 2


Domain annotation for each model (and alignments):
>> Glyco_trans_2_3  Glycosyl transferase family group 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  133.1   1.4   6.4e-43   1.1e-38       1     197 []     260     494 ..     260     494 .. 0.83

  Alignments for each domain:
  == domain 1  score: 133.1 bits;  conditional E-value: 6.4e-43
  Glyco_trans_2_3   1 iilllDaDtvlppdclreiaa.elasp...evaivqgpvlvm...nvanwleelaalffaedhgkdilvrealgrvvpsvGsgaflrrsalqev 87 
                      ii+++DaDt+l++d+++ei++ +++++   e+a++  p++++   n  ++l+++a+l     + +++++++++g+++ +++s+++l+++++++v
       EEA19257.1 260 IITVMDADTHLSQDYFNEIRRiHWQQNadaERAFYASPIIFDrnsNDVPVLVRCADL----LWSFAGISAMYPGCPIVIPTSVYSLPLALARRV 349
                      79*******************99*987788999999999997544445555555555....445899*************************** PP

  Glyco_trans_2_3  88 ggwdgdessvsEDfdmglrlqrkG...yrvrfvpes..lvkeksplt.........lraalrQrkRwayGc........el.........ekli 150
                      ggwdgd+++++ED++m l+++ +     +++f++++  +++ +s+ +         l a++rQ+ R+++G+        ++         ++l+
       EEA19257.1 350 GGWDGDTTAIGEDMHMLLKCYFETagdVITHFIASPasQCNIESSGDgnwgpysstLFARYRQALRHMWGAldtgysvrQSvgglsgkgsQRLR 443
                      ********************85555586677775554499888888789**********************87776655225666677766666 PP

  Glyco_trans_2_3 151 llvrllgylgsll.wsalplhlallllfsllalalvl...llllllaalll 197
                      l++r+l++l++l+ ++ lp hl++lllfs l++a+v+   ++++l++a+++
       EEA19257.1 444 LRTRHLALLHLLFeAHFLPSHLTILLLFSALYTAFVPaenIHPTLAWAFFI 494
                      677777777777645669******************************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (599 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       402  (0.0224218); expected 358.6 (0.02)
Passed bias filter:                      345  (0.0192426); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.42
# Mc/sec: 4262.56
//
Query:       EEA19258.1  [L=100]
Description: hypothetical protein PMAA_015160 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (100 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       332  (0.0185175); expected 358.6 (0.02)
Passed bias filter:                      165  (0.00920297); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.41u 0.26s 00:00:00.67 Elapsed: 00:00:00.44
# Mc/sec: 685.16
//
Query:       EEA19259.1  [L=497]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-45  153.7   7.0    2.1e-10   41.0   0.5    5.9  5  Ank_2     Ankyrin repeats (3 copies)
    1.4e-43  146.7  14.1    2.7e-06   27.8   0.0   12.1 13  Ank_4     Ankyrin repeats (many copies)
    3.5e-34  113.0  15.2    0.00027   21.1   0.0   14.2 15  Ank_3     Ankyrin repeat
    8.6e-33  112.0  15.0    9.6e-05   22.6   0.0    9.9 11  Ank_5     Ankyrin repeats (many copies)
    2.9e-22   78.0  20.5      0.013   15.9   0.0   13.1 13  Ank       Ankyrin repeat
  ------ inclusion threshold ------
      0.034   14.3   0.6         16    5.7   0.0    3.8  5  DUF2773   Protein of unknown function (DUF2773)


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8   0.0   1.5e-07   0.00045      38      81 ..       5      67 ..       2      69 .. 0.70
   2 !   38.5   0.1   4.4e-13   1.3e-09      11      81 ..      88     171 ..      76     173 .. 0.80
   3 !   29.6   0.1   2.6e-10   7.7e-07       5      74 ..     184     265 ..     181     275 .. 0.73
   4 !   41.0   0.5   7.1e-14   2.1e-10       2      79 ..     282     370 ..     281     374 .. 0.81
   5 !   21.6   0.0   7.9e-08   0.00024      11      65 ..     430     497 .]     420     497 .] 0.73

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 1.5e-07
       Ank_2 38 nleivklLleh...............ad...ndgr.tpLhyAarsghleivklLlekgadinl 81
                ++e++++Ll++               a+   ++g  +pL++A+ +g++ei+++Llekg d+n 
  EEA19259.1  5 KTEAMEALLKAganpdggmrlalqqgANincKSGAvSPLYLAVLYGNFEIARMLLEKGLDPNE 67
                566777777633334444444444463355756666************************996 PP

  == domain 2  score: 38.5 bits;  conditional E-value: 4.4e-13
       Ank_2  11 elvklLl.egadpn...k...ngktaLhyAakngnleivklLleh...ad...ndgrtpLhyAarsghleivklLlekgadinl 81 
                 +++ lLl +ga+++   +     +taL  Aa +++++ivk+Ll+    ++   ++ + p+++Aa+sg+++ v++Ll+ gad n+
  EEA19259.1  88 KMLGLLLdHGARIEeenNsteYRRTALARAAGKDDVNIVKYLLKRgadVNhagKNSHPPIYAAAWSGNIDSVRVLLKAGADANA 171
                 46667788887776553146788********************967553356688999******************88***985 PP

  == domain 3  score: 29.6 bits;  conditional E-value: 2.6e-10
       Ank_2   5 akngnlelvklLl.egadpn..kngktaLhyAakngnl.ei...vklLleh...ad...ndgrtpLhyAarsghleivklLle 74 
                 a+ +n+++++lLl +gad+n  +++ t Lh+A+   +   i   v+lLle+    +   + g+ pL +++ +++++++ +Lle
  EEA19259.1 184 AY-NNPKIIRLLLkNGADMNaiSDDGTCLHIATFLACDkGIavpVRLLLEAgasRNhrtRLGKRPLDICVLNDNIDAAAVLLE 265
                 34.4478*************8645668888877753221234479****966652244478********************96 PP

  == domain 4  score: 41.0 bits;  conditional E-value: 7.1e-14
       Ank_2   2 hlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh.ad.....ndgrtpLhyAarsghleivklLlekg.adi 79 
                 h+ ++   +elv+ L+ +gad++  + ng t+L++A+ + n+ +v++Ll++ ad     n+ ++ Lh+A+ ++ l +v++L ekg  d+
  EEA19259.1 282 HQISNTTPSELVRKLVnAGADLHssNkNGVTPLQVAVDARNIAVVEYLLSKnADpyrcsNKAHSLLHIACDKNDLSLVRVLAEKGkMDL 370
                 5555544358******9****998537*************9999*****97744555668999*******************9951454 PP

  == domain 5  score: 21.6 bits;  conditional E-value: 7.9e-08
       Ank_2  11 elvklLl.egadpn..k.ngktaLhyAakngnleivklLleh...........adndgrtpLhyAarsgh 65 
                 + +++Ll +ga+pn  +  g+ +Lh+A  +++l    +L+++            d+ gr+p+h+Aa  gh
  EEA19259.1 430 PQFQYLLeHGANPNieDsSGRRPLHFASLATSL--TDILVSFkaetlvngqppRDKMGRNPIHFAAVGGH 497
                 5689***999***99637***********9955..4555543333343336777799********97665 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   5.5e-06     0.017      17      55 .]      23      59 ..       2      59 .. 0.86
   2 !   17.0   0.0   2.2e-06    0.0067       3      54 ..      41      93 ..      39      94 .. 0.82
   3 ?   -0.7   0.0      0.78   2.3e+03      14      27 ..      87     100 ..      85     106 .. 0.84
   4 !   27.8   0.0   9.2e-10   2.7e-06       1      55 []     110     163 ..     110     163 .. 0.95
   5 !   15.6   0.1   6.1e-06     0.018      11      42 ..     185     214 ..     177     217 .. 0.88
   6 !   13.9   0.1     2e-05      0.06      17      55 .]     227     264 ..     226     264 .. 0.96
   7 !   11.8   0.0   9.4e-05      0.28      13      40 ..     256     282 ..     255     283 .. 0.94
   8 !   26.7   0.0     2e-09   5.9e-06       2      55 .]     278     330 ..     278     330 .. 0.97
   9 !   18.4   0.4   8.2e-07    0.0024       8      54 ..     317     362 ..     316     363 .. 0.89
  10 !   10.6   0.1   0.00023      0.68       2      29 ..     344     372 ..     343     386 .. 0.80
  11 ?    4.7   0.0     0.016        48      11      35 ..     392     416 ..     379     429 .. 0.77
  12 !   17.6   0.0   1.5e-06    0.0044      12      43 ..     427     457 ..     418     462 .. 0.85
  13 !    5.9   0.0    0.0066        20      16      46 ..     462     496 ..     459     497 .] 0.84

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 5.5e-06
       Ank_4 17 vrlLlekgadinaqdnrsGe.talhiAakrgnveilklLl 55
                 rl l++ga+in+    sG  ++l+ A++ gn+ei+++Ll
  EEA19259.1 23 MRLALQQGANINCK---SGAvSPLYLAVLYGNFEIARMLL 59
                5889999******9...55559*****************8 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 2.2e-06
       Ank_4  3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrg..nveilklL 54
                ++L  a+ +g++e++r Llekg d+n+  ++    +l  A+  g  ++++l lL
  EEA19259.1 41 SPLYLAVLYGNFEIARMLLEKGLDPNEN-PEGSSLPLLLALELGprSIKMLGLL 93
                57778888*******************9.9988889999987665457777666 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 0.78
       Ank_4  14 lelvrlLlekgadi 27 
                 ++++ lLl++ga i
  EEA19259.1  87 IKMLGLLLDHGARI 100
                 68999******987 PP

  == domain 4  score: 27.8 bits;  conditional E-value: 9.2e-10
       Ank_4   1 eltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++taL +aa + ++ +v++Ll +gad+n+   ++  ++++ Aa+ gn++ ++ Ll
  EEA19259.1 110 RRTALARAAGKDDVNIVKYLLKRGADVNHA-GKNSHPPIYAAAWSGNIDSVRVLL 163
                 5899*************************8.999999***************997 PP

  == domain 5  score: 15.6 bits;  conditional E-value: 6.1e-06
       Ank_4  11 sgrlelvrlLlekgadinaqdnrsGetalhiA 42 
                 +++ +++rlLl +gad na   +++ t+lhiA
  EEA19259.1 185 YNNPKIIRLLLKNGADMNAI--SDDGTCLHIA 214
                 78999**************9..5689*****9 PP

  == domain 6  score: 13.9 bits;  conditional E-value: 2e-05
       Ank_4  17 vrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 vrlLle ga+ n++  r G  +l+i++++ n++++  Ll
  EEA19259.1 227 VRLLLEAGASRNHR-TRLGKRPLDICVLNDNIDAAAVLL 264
                 89************.*******************99887 PP

  == domain 7  score: 11.8 bits;  conditional E-value: 9.4e-05
       Ank_4  13 rlelvrlLlekgadinaqdnrsGetalh 40 
                 ++++++ Lle+++ i+++ ++ ++t lh
  EEA19259.1 256 NIDAAAVLLEFRVPIDYT-DDKDNTVLH 282
                 7899**************.999*****9 PP

  == domain 8  score: 26.7 bits;  conditional E-value: 2e-09
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +t+Lh+  +  + elvr L++ gad++ + n++G t+l+ A+   n+ ++++Ll
  EEA19259.1 278 NTVLHQISNTTPSELVRKLVNAGADLHSS-NKNGVTPLQVAVDARNIAVVEYLL 330
                 599*************************9.***********************8 PP

  == domain 9  score: 18.4 bits;  conditional E-value: 8.2e-07
       Ank_4   8 aaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54 
                 a+ + ++ +v++Ll+k+ad++++ ++   ++lhiA+ +++++ ++ L
  EEA19259.1 317 AVDARNIAVVEYLLSKNADPYRC-SNKAHSLLHIACDKNDLSLVRVL 362
                 56678999***************.665889************99988 PP

  == domain 10  score: 10.6 bits;  conditional E-value: 0.00023
       Ank_4   2 ltaLhyaaisgrlelvrlLlek.gadina 29 
                 +++Lh a+ +++l lvr L ek ++d+  
  EEA19259.1 344 HSLLHIACDKNDLSLVRVLAEKgKMDLQL 372
                 589*******************5577655 PP

  == domain 11  score: 4.7 bits;  conditional E-value: 0.016
       Ank_4  11 sgrlelvrlLlekgad.inaqdnrsG 35 
                 + ++el+++L+++g+d + ++ +r+ 
  EEA19259.1 392 EPNMELLAYLVDTGKDnLQHR-SRNL 416
                 679************966666.5555 PP

  == domain 12  score: 17.6 bits;  conditional E-value: 1.5e-06
       Ank_4  12 grlelvrlLlekgadinaqdnrsGetalhiAa 43 
                  + +  ++Lle+ga++n   ++sG+ +lh+A 
  EEA19259.1 427 RHKPQFQYLLEHGANPNIE-DSSGRRPLHFAS 457
                 5666779***********5.***********7 PP

  == domain 13  score: 5.9 bits;  conditional E-value: 0.0066
       Ank_4  16 lvrlLlekgad..inaqdnrs..GetalhiAakrg 46 
                 l ++L++++a+  +n q++r+  G++++h+Aa +g
  EEA19259.1 462 LTDILVSFKAEtlVNGQPPRDkmGRNPIHFAAVGG 496
                 56789999999999***99998888******9666 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0      0.36   1.1e+03      13      30 ..       4      20 ..       1      21 [. 0.85
   2 ?   -2.2   0.0       3.6   1.1e+04      19      31 .]      24      35 ..      22      35 .. 0.80
   3 !   21.1   0.0     9e-08   0.00027       4      30 ..      41      66 ..      40      67 .. 0.96
   4 ?    4.9   0.1     0.017        51       5      29 ..      75     100 ..      73     102 .. 0.84
   5 !   18.2   0.0   7.9e-07    0.0024       2      31 .]     110     138 ..     109     138 .. 0.95
   6 ?    4.1   0.0     0.031        93       8      31 .]     149     171 ..     143     171 .. 0.82
   7 !    7.5   0.1    0.0024       7.2      12      30 ..     185     202 ..     182     203 .. 0.86
   8 ?    2.5   0.0      0.11   3.2e+02       4      30 ..     209     238 ..     206     239 .. 0.70
   9 ?    3.9   0.0     0.036   1.1e+02       2      29 ..     244     270 ..     243     271 .. 0.87
  10 !    5.8   0.0    0.0091        27       3      30 ..     278     304 ..     276     305 .. 0.93
  11 !   16.2   0.0   3.7e-06     0.011       1      30 [.     309     337 ..     309     338 .. 0.95
  12 !   12.0   0.0   8.4e-05      0.25       4      29 ..     345     370 ..     344     372 .. 0.89
  13 ?    4.9   0.0     0.017        52      18      31 .]     432     444 ..     416     444 .. 0.80
  14 ?    3.0   0.0     0.074   2.2e+02       2      17 ..     449     465 ..     448     477 .. 0.82
  15 ?    0.7   0.0      0.39   1.2e+03       2      13 ..     485     496 ..     484     497 .] 0.83

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.36
       Ank_3 13 gnleivkfLlenkgadvn 30
                g++e +++Ll+  ga+++
  EEA19259.1  4 GKTEAMEALLK-AGANPD 20
                778899*****.8*9987 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 3.6
       Ank_3 19 kfLlenkgadvna 31
                ++ l+  ga++n+
  EEA19259.1 24 RLALQ-QGANINC 35
                66788.8****96 PP

  == domain 3  score: 21.1 bits;  conditional E-value: 9e-08
       Ank_3  4 tpLhlAarsgnleivkfLlenkgadvn 30
                +pL+lA+++gn+ei+++Lle kg d+n
  EEA19259.1 41 SPLYLAVLYGNFEIARMLLE-KGLDPN 66
                8*******************.9****9 PP

  == domain 4  score: 4.9 bits;  conditional E-value: 0.017
       Ank_3   5 pLhlAarsgnle..ivkfLlenkgadv 29 
                 pL lA++ g+ +  ++ +Ll+ +ga +
  EEA19259.1  75 PLLLALELGPRSikMLGLLLD-HGARI 100
                 9**********7458999*99.89865 PP

  == domain 5  score: 18.2 bits;  conditional E-value: 7.9e-07
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvna 31 
                  +t+L +Aa  ++++ivk+Ll+ +gadvn+
  EEA19259.1 110 RRTALARAAGKDDVNIVKYLLK-RGADVNH 138
                 58********************.*****96 PP

  == domain 6  score: 4.1 bits;  conditional E-value: 0.031
       Ank_3   8 lAarsgnleivkfLlenkgadvna 31 
                  Aa sgn++ v+ Ll+  gad na
  EEA19259.1 149 AAAWSGNIDSVRVLLK-AGADANA 171
                 5666899988******.9***996 PP

  == domain 7  score: 7.5 bits;  conditional E-value: 0.0024
       Ank_3  12 sgnleivkfLlenkgadvn 30 
                 ++n++i+++Ll+ +gad n
  EEA19259.1 185 YNNPKIIRLLLK-NGADMN 202
                 899999******.8**965 PP

  == domain 8  score: 2.5 bits;  conditional E-value: 0.11
       Ank_3   4 tpLhlAarsgnle.i...vkfLlenkgadvn 30 
                 t Lh+A   ++ + i   v++Lle  ga  n
  EEA19259.1 209 TCLHIATFLACDKgIavpVRLLLE-AGASRN 238
                 788866666666443446******.898776 PP

  == domain 9  score: 3.9 bits;  conditional E-value: 0.036
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadv 29 
                 G  pL ++++++n++ +  Lle + +++
  EEA19259.1 244 GKRPLDICVLNDNIDAAAVLLE-FRVPI 270
                 6679*****************9.77766 PP

  == domain 10  score: 5.8 bits;  conditional E-value: 0.0091
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvn 30 
                 +t Lh+    ++ e+v+ L++  gad++
  EEA19259.1 278 NTVLHQISNTTPSELVRKLVN-AGADLH 304
                 89*******************.8***86 PP

  == domain 11  score: 16.2 bits;  conditional E-value: 3.7e-06
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvn 30 
                 nG tpL +A+ + n+++v++Ll  k+ad++
  EEA19259.1 309 NGVTPLQVAVDARNIAVVEYLLS-KNADPY 337
                 799********************.9***96 PP

  == domain 12  score: 12.0 bits;  conditional E-value: 8.4e-05
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadv 29 
                 ++Lh+A+  ++l++v+ L e+  +d+
  EEA19259.1 345 SLLHIACDKNDLSLVRVLAEKGKMDL 370
                 89******************777775 PP

  == domain 13  score: 4.9 bits;  conditional E-value: 0.017
       Ank_3  18 vkfLlenkgadvna 31 
                  ++Lle +ga++n+
  EEA19259.1 432 FQYLLE-HGANPNI 444
                 79****.9****97 PP

  == domain 14  score: 3.0 bits;  conditional E-value: 0.074
       Ank_3   2 GetpLhlAarsgnle.i 17 
                 G+ pLh+A ++++l+ i
  EEA19259.1 449 GRRPLHFASLATSLTdI 465
                 899******99998543 PP

  == domain 15  score: 0.7 bits;  conditional E-value: 0.39
       Ank_3   2 GetpLhlAarsg 13 
                 G++p+h+Aa  g
  EEA19259.1 485 GRNPIHFAAVGG 496
                 99******9755 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.0   7.2e-08   0.00021       5      45 ..      30      68 ..      26      79 .. 0.76
   2 !   16.6   0.0   2.4e-06    0.0072      10      43 ..     104     137 ..      93     141 .. 0.83
   3 !   10.7   0.1   0.00018      0.53      19      44 ..     146     171 ..     140     174 .. 0.91
   4 !    6.7   0.0    0.0031       9.2      26      52 ..     185     210 ..     181     214 .. 0.74
   5 ?    1.3   0.0      0.15   4.6e+02      32      55 ..     227     250 ..     218     251 .. 0.89
   6 !    9.8   0.1   0.00034         1       1      53 [.     230     281 ..     230     283 .. 0.86
   7 !   22.6   0.0   3.2e-08   9.6e-05       1      56 []     263     317 ..     263     317 .. 0.95
   8 !   19.7   0.1   2.6e-07   0.00079       1      42 [.     296     336 ..     296     346 .. 0.89
   9 !   10.7   0.0   0.00018      0.53      18      46 ..     345     374 ..     335     376 .. 0.80
  10 !   15.3   0.0   6.3e-06     0.019       1      26 [.     435     459 ..     435     472 .. 0.87
  11 ?    1.2   0.0      0.17   5.1e+02      16      27 ..     485     496 ..     474     497 .] 0.75

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 7.2e-08
       Ank_5  5 gpadvnrldgggntpLhvAakygaadvvrlLlargadlnlt 45
                g a++n++ g  ++pL +A+ yg+++++r+Ll+ g+d+n  
  EEA19259.1 30 G-ANINCKSGA-VSPLYLAVLYGNFEIARMLLEKGLDPNEN 68
                5.666666544.6************************9975 PP

  == domain 2  score: 16.6 bits;  conditional E-value: 2.4e-06
       Ank_5  10 nrldgggntpLhvAakygaadvvrlLlargadln 43 
                 n++ +++ t+L  Aa +   ++v++Ll+rgad n
  EEA19259.1 104 NNSTEYRRTALARAAGKDDVNIVKYLLKRGADVN 137
                 44555666************************97 PP

  == domain 3  score: 10.7 bits;  conditional E-value: 0.00018
       Ank_5  19 pLhvAakygaadvvrlLlargadlnl 44 
                 p+  Aa+ g+ d vr+Ll+ gad+n+
  EEA19259.1 146 PIYAAAWSGNIDSVRVLLKAGADANA 171
                 6778999*****************97 PP

  == domain 4  score: 6.7 bits;  conditional E-value: 0.0031
       Ank_5  26 ygaadvvrlLlargadlnltdsrGlta 52 
                 y+++ ++rlLl++gad n+  ++G t 
  EEA19259.1 185 YNNPKIIRLLLKNGADMNAISDDG-TC 210
                 888899999999999999888887.44 PP

  == domain 5  score: 1.3 bits;  conditional E-value: 0.15
       Ank_5  32 vrlLlargadlnltdsrGltaldl 55 
                 vrlLl+ ga++n ++  G+ +ld+
  EEA19259.1 227 VRLLLEAGASRNHRTRLGKRPLDI 250
                 78999*******999999999998 PP

  == domain 6  score: 9.8 bits;  conditional E-value: 0.00034
       Ank_5   1 Llehg.padvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltal 53 
                 Lle+g ++++ r++ g+  pL + + + + d + +Ll++++ ++ td+  +t+l
  EEA19259.1 230 LLEAGaSRNH-RTRLGK-RPLDICVLNDNIDAAAVLLEFRVPIDYTDDKDNTVL 281
                 8999944444.556665.*****************************9999988 PP

  == domain 7  score: 22.6 bits;  conditional E-value: 3.2e-08
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 Lle + + ++++d + nt+Lh+ ++   +++vr+L++ gadl   +++G t+l++A
  EEA19259.1 263 LLEFR-VPIDYTDDKDNTVLHQISNTTPSELVRKLVNAGADLHSSNKNGVTPLQVA 317
                 67777.88899*******************************************98 PP

  == domain 8  score: 19.7 bits;  conditional E-value: 2.6e-07
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadl 42 
                 L+++g ad+  ++++g+tpL vA+ +++  vv++Ll  +ad+
  EEA19259.1 296 LVNAG-ADLHSSNKNGVTPLQVAVDARNIAVVEYLLSKNADP 336
                 78999.******************************777766 PP

  == domain 9  score: 10.7 bits;  conditional E-value: 0.00018
       Ank_5  18 tpLhvAakygaadvvrlLl.argadlnltd 46 
                 + Lh+A+ ++ +++vr+L  +  +dl l d
  EEA19259.1 345 SLLHIACDKNDLSLVRVLAeKGKMDLQLAD 374
                 78****************977777776655 PP

  == domain 10  score: 15.3 bits;  conditional E-value: 6.3e-06
       Ank_5   1 LlehgpadvnrldgggntpLhvAaky 26 
                 Llehg a++n +d  g  pLh+A+ +
  EEA19259.1 435 LLEHG-ANPNIEDSSGRRPLHFASLA 459
                 8****.*****************985 PP

  == domain 11  score: 1.2 bits;  conditional E-value: 0.17
       Ank_5  16 gntpLhvAakyg 27 
                 g +p+h+Aa +g
  EEA19259.1 485 GRNPIHFAAVGG 496
                 669*****9655 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0      0.34     1e+03      12      28 ..       3      20 ..       2      20 .. 0.79
   2 ?   -1.5   0.0       1.4   4.2e+03      22      30 ..      27      36 ..      25      37 .. 0.77
   3 !    9.7   0.0    0.0004       1.2       4      28 ..      41      66 ..      40      68 .. 0.90
   4 ?    1.8   0.1      0.13   3.9e+02       6      25 ..      76      98 ..      75     105 .. 0.67
   5 !   15.9   0.0   4.3e-06     0.013       3      29 ..     111     138 ..     109     141 .. 0.87
   6 !   11.4   1.1   0.00011      0.34      11      30 ..     184     204 ..     145     206 .. 0.83
   7 ?    4.2   0.1     0.023        68       4      31 ..     209     241 ..     209     242 .. 0.66
   8 ?    2.7   0.0     0.064   1.9e+02       3      31 ..     278     307 ..     276     308 .. 0.73
   9 !   11.4   0.0   0.00012      0.35       1      27 [.     309     336 ..     309     341 .. 0.82
  10 ?    3.7   0.1     0.031        93       4      22 ..     345     363 ..     344     376 .. 0.72
  11 !    7.9   0.0    0.0015       4.5      19      31 ..     433     446 ..     426     447 .. 0.90
  12 ?   -0.3   0.0      0.59   1.8e+03       3      10 ..     450     457 ..     448     472 .. 0.73
  13 ?   -0.0   0.1      0.49   1.5e+03       1      13 [.     484     496 ..     484     497 .] 0.81

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.34
                HTTHHHHHHHH.TTTSTT CS
         Ank 12 ngkkriiklLL.hGAnln 28
                 gk++  ++LL  GAn++
  EEA19259.1  3 WGKTEAMEALLkAGANPD 20
                577778899**77***96 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1.4
                H.TTTSTTCB CS
         Ank 22 L.hGAnlnal 30
                L +GAn+n +
  EEA19259.1 27 LqQGANINCK 36
                557****975 PP

  == domain 3  score: 9.7 bits;  conditional E-value: 0.0004
                BHHHHHHHHTTHHHHHHHH.TTTSTT CS
         Ank  4 TPLHlAatngkkriiklLL.hGAnln 28
                +PL lA+ +g+ +i+++LL +G ++n
  EEA19259.1 41 SPLYLAVLYGNFEIARMLLeKGLDPN 66
                7******************8897776 PP

  == domain 4  score: 1.8 bits;  conditional E-value: 0.13
                HHHHH.....HHTTHHHHHHHH.TTT CS
         Ank  6 LHlAa.....tngkkriiklLL.hGA 25
                L lA      +++   ++ lLL hGA
  EEA19259.1 76 LLLALelgprSIK---MLGLLLdHGA 98
                5565455444566...88999999*9 PP

  == domain 5  score: 15.9 bits;  conditional E-value: 4.3e-06
                 BBHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   3 nTPLHlAatngkkriiklLL.hGAnlna 29 
                 +T+L +Aa  ++++i+k+LL +GA++n 
  EEA19259.1 111 RTALARAAGKDDVNIVKYLLkRGADVNH 138
                 69******6677********88****96 PP

  == domain 6  score: 11.4 bits;  conditional E-value: 0.00011
                 HHTTHHHHHHHH.TTTSTTCB CS
         Ank  11 tngkkriiklLL.hGAnlnal 30 
                  ++++ ii+lLL +GA+ na 
  EEA19259.1 184 AYNNPKIIRLLLkNGADMNAI 204
                 478899******88****985 PP

  == domain 7  score: 4.2 bits;  conditional E-value: 0.023
                 BHHHHH....HHHTTHHHH...HHHH.TTTSTTCBT CS
         Ank   4 TPLHlA....atngkkrii...klLL.hGAnlnald 31 
                 T+LH+A    +  g   i+   +lLL  GA+ n ++
  EEA19259.1 209 TCLHIAtflaCDKG---IAvpvRLLLeAGASRNHRT 241
                 89998633324555...4444499998899999876 PP

  == domain 8  score: 2.7 bits;  conditional E-value: 0.064
                 BBHHHHHH..HHTTHHHHHHHH.TTTSTTCBT CS
         Ank   3 nTPLHlAa..tngkkriiklLL.hGAnlnald 31 
                 nT+LH  +  t+   + ++ L+  GA+l++ +
  EEA19259.1 278 NTVLHQISntTP--SELVRKLVnAGADLHSSN 307
                 899996355533..3799999*779**98765 PP

  == domain 9  score: 11.4 bits;  conditional E-value: 0.00012
                 TSBBHHHHHH...HHTTHHHHHHHH.TTTST CS
         Ank   1 dGnTPLHlAa...tngkkriiklLL.hGAnl 27 
                 +G TPL +A+   +++   ++++LL + A++
  EEA19259.1 309 NGVTPLQVAVdarNIA---VVEYLLsKNADP 336
                 7********9666666...******667998 PP

  == domain 10  score: 3.7 bits;  conditional E-value: 0.031
                 BHHHHHHHHTTHHHHHHHH CS
         Ank   4 TPLHlAatngkkriiklLL 22 
                 + LH+A+  ++++ ++ L 
  EEA19259.1 345 SLLHIACDKNDLSLVRVLA 363
                 67*****878788888774 PP

  == domain 11  score: 7.9 bits;  conditional E-value: 0.0015
                 HHHH.TTTSTTCBT CS
         Ank  19 klLL.hGAnlnald 31 
                 ++LL hGAn+n+ d
  EEA19259.1 433 QYLLeHGANPNIED 446
                 78*********998 PP

  == domain 12  score: -0.3 bits;  conditional E-value: 0.59
                 BBHHHHHH CS
         Ank   3 nTPLHlAa 10 
                 + PLH A+
  EEA19259.1 450 RRPLHFAS 457
                 559**998 PP

  == domain 13  score: -0.0 bits;  conditional E-value: 0.49
                 TSBBHHHHHHHHT CS
         Ank   1 dGnTPLHlAatng 13 
                 +G+ P H Aa +g
  EEA19259.1 484 MGRNPIHFAAVGG 496
                 6999****99665 PP

>> DUF2773  Protein of unknown function (DUF2773)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       1.9   5.8e+03      32      65 ..     134     167 ..     131     171 .. 0.77
   2 ?   -3.0   0.1       2.8   8.2e+03      22      30 ..     182     190 ..     173     199 .. 0.69
   3 ?   -1.7   0.0       1.1   3.3e+03      55      65 ..     291     301 ..     275     304 .. 0.76
   4 ?    5.7   0.0    0.0054        16      39      65 ..     341     367 ..     321     372 .. 0.86
   5 ?    4.0   0.0     0.018        53      39      66 ..     376     407 ..     368     416 .. 0.80

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 1.9
     DUF2773  32 vdvkkarlkedPllllelvqPeldllrdlvktGk 65 
                 +dv +a     P +       ++d +r l k+G+
  EEA19259.1 134 ADVNHAGKNSHPPIYAAAWSGNIDSVRVLLKAGA 167
                 6777777777777777777888999999999987 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 2.8
     DUF2773  22 ilainnPrl 30 
                 i a nnP++
  EEA19259.1 182 ISAYNNPKI 190
                 457788875 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 1.1
     DUF2773  55 dllrdlvktGk 65 
                 +l+r+lv +G+
  EEA19259.1 291 ELVRKLVNAGA 301
                 79*****9997 PP

  == domain 4  score: 5.7 bits;  conditional E-value: 0.0054
     DUF2773  39 lkedPllllelvqPeldllrdlvktGk 65 
                  k   ll +   + +l+l+r l+ +Gk
  EEA19259.1 341 NKAHSLLHIACDKNDLSLVRVLAEKGK 367
                 577788999999*************98 PP

  == domain 5  score: 4.0 bits;  conditional E-value: 0.018
     DUF2773  39 lkedPllllelv....qPeldllrdlvktGkt 66 
                 +k  P+ll+ lv    +P+++ll  lv tGk 
  EEA19259.1 376 IKGAPSLLMTLVetwrEPNMELLAYLVDTGKD 407
                 78889999998734446*************85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (497 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       376  (0.0209716); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.59u 0.26s 00:00:00.85 Elapsed: 00:00:00.43
# Mc/sec: 3468.31
//
Query:       EEA19260.1  [L=474]
Description: hypothetical protein PMAA_015180 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (474 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       373  (0.0208043); expected 358.6 (0.02)
Passed bias filter:                      344  (0.0191868); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.24s 00:00:00.74 Elapsed: 00:00:00.40
# Mc/sec: 3534.13
//
Query:       EEA19261.1  [L=1737]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.4e-10   40.5   0.0    4.1e-10   39.7   0.0    1.3  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    3.7e-09   36.8   0.4    1.6e-08   34.8   0.1    2.4  2  rve              Integrase core domain
    5.1e-06   26.3   1.1    1.7e-05   24.6   1.1    1.8  1  gag_pre-integrs  GAG-pre-integrase domain


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.7   0.0   6.8e-14   4.1e-10       7     182 ..    1228    1407 ..    1221    1468 .. 0.78

  Alignments for each domain:
  == domain 1  score: 39.7 bits;  conditional E-value: 6.8e-14
       RVT_2    7 slPkdrkaigsrWvftkkkddlkevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeeelvv.hqldvdsafLnae..ldeevyvkqP 100 
                  + P + +   +r+v  +k+   +++  k+rlv+q ++   +++y  + +P i+  s r++l l    e v  +  d+  a+++++  l+ + y++  
  EEA19261.1 1228 DIPPGTRIFTARFVNDIKNPGTDKAFEKSRLVVQAYND-GDKEYVLTQSPTIQRASQRIILCLGMIVENVRyYIRDITQAYIQSTtkLNRDFYIRIT 1323
                  5688899999********9999**************86.6789********************987666650556*******997225566999998 PP

       RVT_2  101 pGfeidreeekvykLnkslyGlkqapllWnekidk.vLkklgferseaesGlyvrgtgegk.livalyvddlliagsdikiled 182 
                               k+ + lyG+  a+  W+++ ++   +kl+ e s+    l   +++++   iv++  dd li+++d+  + +
  EEA19261.1 1324 QDLAEYFPGATFLKVVRPLYGIPEAGNHWFRTYHNhHTEKLNIETSTYDPCLLHCSDSKQGfGIVGMQTDDTLIVANDTFAVRE 1407
                  8888777778889****************998765167899******9999876666655538*************99866654 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0       1.4   8.4e+03      41      67 ..     490     519 ..     486     541 .. 0.68
   2 !   34.8   0.1   2.6e-12   1.6e-08       8     117 ..     844     946 ..     838     948 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 1.4
         rve  41 alsdemdastvlalleravarfggve...p 67 
                  +++e+++++++ +l+ra a+f+  e   p
  EEA19261.1 490 NHTKEEQQAAIQLFLDRAKAYFAAGEeqpP 519
                 567778999999999999999987666543 PP

  == domain 2  score: 34.8 bits;  conditional E-value: 2.6e-12
         rve   8 wqvDvtvvripdgggkayllvvvddfsrlilaealsdemdastvlalleravarfggvepervlsDngseytskafrefladlgirvsftrpgrpqdnG 106
                 + vD+++++    g  + +l+vvd ++r+  a+ l++ ++++t++al  + ++ + g  p+ +++D g+ +tsk+f + + +++i+v++ ++   ++ G
  EEA19261.1 844 IIVDIMYIN----G--KPVLHVVDEATRFNAAHWLDNISAKATWTALRIMWIDMYLGP-PDFIITDAGKNFTSKEFSQNALSMNITVTTVPVEAHWSIG 935
                 567888888....3..468899****************9******************9.**************************************** PP

         rve 107 kvErfhrtlkd 117
                  vEr h  l++
  EEA19261.1 936 TVERYHAVLRR 946
                 ******99987 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.6   1.1   2.8e-09   1.7e-05      20      64 ..     775     822 ..     759     824 .. 0.81

  Alignments for each domain:
  == domain 1  score: 24.6 bits;  conditional E-value: 2.8e-09
  gag_pre-integrs  20 nkssinlWHrRLGHpsfsrlkkLfkkgllpglkisk....sevCeaCql 64 
                      +++++++ HrR+GHps+++l+++ +  + ++++ +      +vC++Cq+
       EEA19261.1 775 TETELRRLHRRFGHPSVEKLRRMLE-RAGHNVDSEAlkhiRKVCHHCQI 822
                      6789999*****************8.5888888766435566*****96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1737 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       594  (0.0331307); expected 358.6 (0.02)
Passed bias filter:                      436  (0.0243181); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.97u 0.29s 00:00:01.26 Elapsed: 00:00:00.48
# Mc/sec: 10857.36
//
Query:       EEA19262.1  [L=337]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (337 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       383  (0.021362); expected 358.6 (0.02)
Passed bias filter:                      361  (0.020135); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.56u 0.30s 00:00:00.86 Elapsed: 00:00:00.53
# Mc/sec: 1927.30
//
Query:       EEA19263.1  [L=749]
Description: hypothetical protein PMAA_015210 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.8e-08   32.1   0.0     0.0056   16.0   0.0    2.7  3  Peptidase_S8  Subtilase family
    0.00013   22.5   0.0        1.7    9.3   0.0    3.1  3  Ank_2         Ankyrin repeats (3 copies)
     0.0062   16.9   0.0        2.9    8.5   0.0    3.7  3  Ank           Ankyrin repeat
     0.0078   16.3   0.0      0.021   14.9   0.0    1.8  1  Gemini_AL1_M  Geminivirus rep protein central domain
  ------ inclusion threshold ------
      0.037   14.6   0.0        2.2    9.0   0.0    2.9  2  Ank_4         Ankyrin repeats (many copies)
      0.051   14.0   0.0        4.6    7.7   0.0    2.7  2  Tfb2_C        Transcription factor Tfb2 (p52) C-terminal doma
        0.1   13.2   0.0         33    5.5   0.0    4.2  4  Ank_3         Ankyrin repeat


Domain annotation for each model (and alignments):
>> Peptidase_S8  Subtilase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -5.2   1.6         6   1.5e+04      28      58 ..      10      40 ..       4      47 .. 0.80
   2 !   16.0   0.0   2.2e-06    0.0056      41     161 ..     475     583 ..     384     584 .. 0.65
   3 !   13.2   0.0   1.6e-05      0.04     214     262 ..     586     633 ..     582     648 .. 0.79

  Alignments for each domain:
  == domain 1  score: -5.2 bits;  conditional E-value: 6
                  .EEEE---TTSG.GGEETT-SS-TT-SC-SS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8 28 rklvdvideegagfngadsettstnwarddn 58
                    ++dv+d+++++++++d  t+s+ +++dd 
    EEA19263.1 10 HVMDDVEDDSVKELDRDDDSTGSEGSDDDDS 40
                  5688999999999999999999888888885 PP

  == domain 2  score: 16.0 bits;  conditional E-value: 2.2e-06
                   GGEETT-SS-TT-SC-SSS....HHHHHHHHHH-B..SSSSSB-SSTTSEEE..EEE-SSTTSB-HH....HHHHHHHHHHHHCT-SEEEE-EESCE CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8  41 fngadsettstnwarddngnsieHGthvAGiaaanapeegekngvapgakil..svkvldtsggsmetg..teliraieeaaedkvdvinmslgest 133
                   + +++ ++   +w++++      HGt +A +++           ++p aki+  ++ + +++ + +     +  ++ai+ a+e++v++i+ms++   
    EEA19263.1 475 LYYDQRDQRAKQWYVSETA----HGTVMAHMILC----------ICPMAKIYpiKLDISKDPTTGASRIkpESAAAAIDAAVEKGVHIISMSWTVNE 557
                   5555666666777777766....88777766655..........599999995544466555555555554555555666666***********555 PP

                   TTCHHCHHHHHHHHHHHH.CCT-EEEEE CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8 134 slpktgrsiealainravnkkgvlvviS 161
                    +++++++    a+ +a  +kg+l+ +S
    EEA19263.1 558 PQNEFKTKFD-EALSNAS-QKGILIWVS 583
                   5555555444.3888888.789999877 PP

  == domain 3  score: 13.2 bits;  conditional E-value: 1.6e-05
                   ..-EEEE-S-CCCCCCCCCHHHTTTHHEEEE-SHHHCHHHHHHHHHHHH CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8 214 kpdivapGgnivstwsrqsnnsaglssyqsmsGTSmAsPnaagaaAlll 262
                   k+d ++pG+++v+  +++ +   g  + ++++G+S ++++aag aAl+l
    EEA19263.1 586 KVDFLFPGMDVVQANKKDIK-LRGVEDRKAETGSSISTALAAGLAALVL 633
                   99********5555555553.33444479******************97 PP

>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.0   0.00066       1.7      27      73 ..     100     161 ..      80     172 .. 0.62
   2 !    9.2   0.0   0.00069       1.8      10      41 ..     202     241 ..     183     265 .. 0.56
   3 ?   -1.2   0.0       1.2   3.2e+03      29      79 ..     537     596 ..     522     600 .. 0.67

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00066
       Ank_2  27 ktaLhyAakngnlei..vklLleh..............adndgrtpLhyAarsghleivk.lLl 73 
                 +++Lh+ +k ++  +   k L ++              ++++  tpL+yA+++   +  k +L+
  EEA19263.1 100 ESILHLIVKDDDATAdeTKELAKAikyivrlypklmttQNKQLFTPLYYAVEN-M-DRRKaYLI 161
                 68888888876443233444444222333335668766669999*******75.2.33333555 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00069
       Ank_2  10 lelvklLlegadpn....k..ngktaLhyAakngnl..ei 41 
                 + +++lL+++ad      k    +t+Lh A+++ +   e+
  EEA19263.1 202 YTVLNLLIASADRQavnaKdaHAWTPLHRATQYEHSseEM 241
                 3466666644442222231345677777777765432233 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 1.2
       Ank_2  29 aLhyAakngnlei..vklLleh.ad..ndgr.tpLhyAarsg.....hleivklLlekgadi 79 
                 a+ +A+++g  +i  +++ +++ ++  ++    +L +A+++g     +l+ v++L+  g d+
  EEA19263.1 537 AIDAAVEKGV-HIisMSWTVNEpQNefKTKFdEALSNASQKGiliwvSLDKVDFLF-PGMDV 596
                 5557777774.442467777766444423222699999988877777788888887.67776 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.0     0.041   1.1e+02       3      11 ..     143     155 ..     142     222 .. 0.59
   2 !    8.5   0.0    0.0012       2.9       3      29 ..     225     256 ..     225     259 .. 0.81
   3 ?   -3.6   0.0         7   1.8e+04      18      26 ..     440     451 ..     440     454 .. 0.67

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.041
                 BBHHHHHH....H CS
         Ank   3 nTPLHlAa....t 11 
                 +TPL +A+    +
  EEA19263.1 143 FTPLYYAVenmdR 155
                 7999999743331 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0012
                 BBHHHHHHHHTT.....HHHHHHHH.TTTSTTC CS
         Ank   3 nTPLHlAatngk.....kriiklLL.hGAnlna 29 
                 +TPLH+A ++ +     +++i+ L+  G ++++
  EEA19263.1 225 WTPLHRATQYEHsseemLDVIEKLIkMG-EPDS 256
                 6*****9988888899999**9999558.6665 PP

  == domain 3  score: -3.6 bits;  conditional E-value: 7
                 HHHHHT...TTS CS
         Ank  18 iklLLh...GAn 26 
                 +k+LLh   GAn
  EEA19263.1 440 VKELLHlrwGAN 451
                 688885546787 PP

>> Gemini_AL1_M  Geminivirus rep protein central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   8.2e-06     0.021      17      81 ..     185     250 ..     167     259 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 8.2e-06
  Gemini_AL1_M  17 sSkeealeiikeelPkDyvlkldnlesnadkifpeipe..efvppfplssftnlpeemqdWvddelg 81 
                     +e++l+++ + +P  y +  + l+ +ad+   ++++   ++p +  +++++ +eem d +++ + 
    EEA19263.1 185 IHQENYLHRVLKSQPINYTVL-NLLIASADRQAVNAKDahAWTPLHRATQYEHSSEEMLDVIEKLIK 250
                   45799*************885.6788889998776665227******************99887664 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0      0.12     3e+02      30      45 ..     138     152 ..     122     159 .. 0.85
   2 ?    9.0   0.0   0.00085       2.2       6      47 ..     192     236 ..     189     249 .. 0.70

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.12
       Ank_4  30 qdnrsGetalhiAakr 45 
                 q n++ +t+l++A+ +
  EEA19263.1 138 Q-NKQLFTPLYYAVEN 152
                 5.9999*******975 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00085
       Ank_4   6 hyaaisgrlel..vrlLlek..gadinaqdnrsGetalhiAakrgn 47 
                 h+  +s+++ +  + lL+++  ++ +na  ++  +t+lh+A + ++
  EEA19263.1 192 HRVLKSQPINYtvLNLLIASadRQAVNAK-DAHAWTPLHRATQYEH 236
                 5555555555554788884333667***8.999********98777 PP

>> Tfb2_C  Transcription factor Tfb2 (p52) C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.0    0.0018       4.6      15      38 ..     321     343 ..     320     356 .. 0.86
   2 ?    3.1   0.0     0.049   1.3e+02      28      50 ..     564     586 ..     559     595 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0018
      Tfb2_C  15 aeegvlyddFesqadfeevleyak 38 
                 a++gv+yd+F+++ +f+evl+y +
  EEA19263.1 321 ADPGVFYDNFQTT-QFDEVLQYVE 343
                 789*******875.7******976 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.049
      Tfb2_C  28 adfeevleyakelgvllwedeek 50 
                 ++f+e+l+ a ++g+l+w + +k
  EEA19263.1 564 TKFDEALSNASQKGILIWVSLDK 586
                 68****************87665 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.0         7   1.8e+04       3      13 ..     100     110 ..     100     116 .. 0.74
   2 ?   -0.6   0.0       1.2   3.2e+03       4      13 ..     144     153 ..     142     165 .. 0.71
   3 ?    1.4   0.0      0.28   7.2e+02       2      23 ..     187     210 ..     186     216 .. 0.78
   4 ?    5.5   0.0     0.013        33       3      26 ..     225     252 ..     223     254 .. 0.77

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 7
       Ank_3   3 etpLhlAarsg 13 
                 e++Lhl ++ +
  EEA19263.1 100 ESILHLIVKDD 110
                 58899988765 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 1.2
       Ank_3   4 tpLhlAarsg 13 
                 tpL++A+++ 
  EEA19263.1 144 TPLYYAVENM 153
                 9*****9985 PP

  == domain 3  score: 1.4 bits;  conditional E-value: 0.28
       Ank_3   2 GetpLhlAarsgnle..ivkfLle 23 
                 +e+ Lh++++s++++  ++ +L+ 
  EEA19263.1 187 QENYLHRVLKSQPINytVLNLLIA 210
                 67889********96437888886 PP

  == domain 4  score: 5.5 bits;  conditional E-value: 0.013
       Ank_3   3 etpLhlAarsgnl.....eivkfLlenkg 26 
                 +tpLh+A  + +      ++++ L++ +g
  EEA19263.1 225 WTPLHRATQYEHSseemlDVIEKLIK-MG 252
                 8************7644446888887.65 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (749 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       931  (0.051927); expected 358.6 (0.02)
Passed bias filter:                      648  (0.0361426); expected 358.6 (0.02)
Passed Vit filter:                        76  (0.00423894); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.79u 0.32s 00:00:01.11 Elapsed: 00:00:00.49
# Mc/sec: 4575.89
//
Query:       EEA19264.1  [L=244]
Description: short chain oxidoreductase (CsgA), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.4e-26   91.9   0.0    4.6e-26   91.5   0.0    1.1  1  adh_short       short chain dehydrogenase
    7.5e-18   64.9   0.0    9.4e-18   64.6   0.0    1.1  1  adh_short_C2    Enoyl-(Acyl carrier protein) reductase
    5.6e-06   26.4   0.0    7.6e-06   26.0   0.0    1.2  1  KR              KR domain
  ------ inclusion threshold ------
      0.075   13.5   0.0       0.15   12.5   0.0    1.5  1  Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domai
      0.086   12.2   0.0       0.85    9.0   0.0    2.4  2  GDP_Man_Dehyd   GDP-mannose 4,6 dehydratase
      0.096   12.1   0.0       0.27   10.7   0.0    1.8  2  Epimerase       NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.5   0.0   1.5e-29   4.6e-26       3     187 ..       4     190 ..       2     195 .. 0.85

  Alignments for each domain:
  == domain 1  score: 91.5 bits;  conditional E-value: 1.5e-29
                 EEEESTTSHHHHHHHHHHHHTT.-EEEEEESCHHHHHHHHHHHHHT.TSEEEEEE-TTTSHHHHHHHHHHHHHHH.....SSESEEEE---SS--SSGG CS
   adh_short   3 vlvtGassGIGraiakelakeG.akvvvvdrseekleevakelkee.gakalaiqvDvtdreevealvekavkkl.....gkldvLvnNAGitgsgpfs 94 
                  lvtG ++GIG++++++la++  a++  v  ++++ +  +kel e   +++++++++v d+e+++ +v  ++  l     ++ldvL+nNAGi  +g++ 
  EEA19264.1   4 YLVTGSARGIGHELVQQLASKPeAEINTVFATSRAENSRLKELTERyPDRIIFVPLTVGDEESMRYAVPIIATTLkykglKGLDVLINNAGI--VGSVY 100
                 59*****************875233333444444444568888888899******************99998777667779***********..56666 PP

                 GCSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHH CS
   adh_short  95 elseeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdma 187
                   + ++ +++++vN+tg+ ++++++lp + k+++ +++n+     +++ +  aaY  +Kaa+++lt  +++el ++g +    +PG ++Td a
  EEA19264.1 101 AQEMADSDEIFHVNVTGPHMMIQLFLPLLRKGNEKNVINM---LNRYKEFPAAAYKVTKAALNMLTVVWSQELDEEGFTFLYQNPGWLQTDEA 190
                 67777889*********************99999999997...5677788899************************************9966 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.6   0.0   3.1e-21   9.4e-18       1     183 [.       8     194 ..       8     209 .. 0.86

  Alignments for each domain:
  == domain 1  score: 64.6 bits;  conditional E-value: 3.1e-21
                   TTTTSHHHHHHHHHHHT.T-EEEEEESSGGH.HHHHHHHHHHTTSEE..EE--TTSHHHHHHHHHHHHHHH.....SSEEEEEE-----EGCSS-GG CS
  adh_short_C2   1 GaasgIGraiAkalaee.Gaevvltdlneea.kkrveelaeelgaev..lecDVtdeeqvealveevvekf.....gklDilvnnagiapklkgpfl 88 
                   G a+gIG++++++la++  ae+  + +  +a ++r++el+e+++ ++  +++ V dee+++ +v  ++ ++     ++lD+l+nnagi+ +    + 
    EEA19264.1   8 GSARGIGHELVQQLASKpEAEINTVFATSRAeNSRLKELTERYPDRIifVPLTVGDEESMRYAVPIIATTLkykglKGLDVLINNAGIVGS----VY 100
                   789**********996537777766666666689**********99447*************9988887765566789***********99....88 PP

                   GH-HHHHHHHHHHHTHHHHHHHHHHHHHCTSC..CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGST CS
  adh_short_C2  89 etsreefdraldvnlyslfllakaalplmkeg..gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgik 183
                     + ++ d++++vn+++ +++++ +lpl+++g   +++n+  +   + +p  +ay ++Kaal+ lt  +  el ++g +     pg+++T+ a++ +
    EEA19264.1 101 AQEMADSDEIFHVNVTGPHMMIQLFLPLLRKGneKNVINM--LNRYKEFPA-AAYKVTKAALNMLTVVWSQELDEEGFTFLYQNPGWLQTDEANAHA 194
                   9999*************************99966677776..434445554.79************************************9987655 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0   0.0   2.5e-09   7.6e-06       1     121 [.       2     123 ..       2     130 .. 0.74

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 2.5e-09
                 SEEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHT.T-EEEE----TT-HHHHHHHHHHHHHHS..S---E...EEE------ CS
          KR   1 gtylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaeleal.gaevevvaaDvsdkdavealleeikaee..ppikG...vihaAgvlr 93 
                 +tyl+tG + g+G el+++la+k ++++  +  +  + ++++++++el+++   ++ +v++ v d+++++ ++  i ++   + +kG    i+ Ag++ 
  EEA19264.1   2 ATYLVTGSARGIGHELVQQLASKPEAEINTVFAT--S-RAENSRLKELTERyPDRIIFVPLTVGDEESMRYAVPIIATTLkyKGLKGldvLINNAGIVG 97 
                 79********************997777555444..2.2344578888887577****************997666555445555552227999***99 PP

                 ---TTT--HHHHHHHHTTTTHHHHHHHH CS
          KR  94 dklleemtaedleqvlapKvkGawnLhe 121
                     +em ++  +++++  v+G + + +
  EEA19264.1  98 SVYAQEMADS--DEIFHVNVTGPHMMIQ 123
                 9888887654..5677777777666655 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   5.1e-05      0.15      11      46 ..      13      48 ..       6      80 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 5.1e-05
                    HHHHHHHHHHCTSSEEEEEEEESTTTTTSBHHHHSG CS
  Semialdhyde_dh 11 vGqellrlLeehpevelvvllsssrsaGkklaeavk 46
                    +G el++ L+++pe+e+ +++++sr + ++l+e+ +
      EEA19264.1 13 IGHELVQQLASKPEAEINTVFATSRAENSRLKELTE 48
                    79***********************88888877755 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.0   0.00028      0.85       1      70 [.       5      70 ..       5      77 .. 0.89
   2 ?   -0.3   0.0      0.19   5.7e+02     103     126 ..     199     222 ..     186     223 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00028
                   EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHH CS
  GDP_Man_Dehyd  1 LiTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkgDltDssslerl 70
                   L+TG a  iG  l+++L +k    +++v  +s  + +r+++l++    ++ +++ ++   + D++s++ +
     EEA19264.1  5 LVTGSARGIGHELVQQLASKPEAEINTVFATSRAENSRLKELTE----RYPDRIIFVPLTVGDEESMRYA 70
                   8*******************9999999999999999*****986....356899****999999998765 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.19
                    THHHHHHHHHHHHCT..TTSEEEE CS
  GDP_Man_Dehyd 103 vlGtlrLLeairalglekkvrfyq 126
                    ++G+ ++Le++r++g e + rf+ 
     EEA19264.1 199 GTGVGQILEIARRTGQEGNGRFLN 222
                    579999*********999999986 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   8.9e-05      0.27       2      96 ..       5     119 ..       4     141 .. 0.61
   2 ?   -2.6   0.0         1     3e+03     138     158 ..     148     168 ..     137     172 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 8.9e-05
                 EEETTTSHHHHHHHHHHHHCT...SE.EEEEES-STTTTCHHCHHC.....EEEE--TT-HH..........HHHHHHHHHT-SEEEE--S.---H.HH CS
   Epimerase   2 lVtGatGfiGsalvkallekg...ye.vigldrlssasntarledl.....elveldltdrs..........alerlfkeeqpdavihlAa.vggv.aa 79 
                 lVtG +  iG  lv++l++k    ++ v + +r  ++s+ ++l +       +v l + d++           + ++   ++ d+ i+ A+ vg+v a+
  EEA19264.1   5 LVTGSARGIGHELVQQLASKPeaeINtVFATSRA-ENSRLKELTERypdriIFVPLTVGDEEsmryavpiiaTTLKYKGLKGLDVLINNAGiVGSVyAQ 102
                 8********************8664414444444.3333333333379988555555555552222222111333333444677777777765554244 PP

                 HHHSHHHHHHHHTHHHH CS
   Epimerase  80 ssedpadfieknlqgtl 96 
                 ++ d  ++++ n+ g  
  EEA19264.1 103 EMADSDEIFHVNVTGPH 119
                 56666666777776655 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1
                 -SSHHHHHHHHHHHHHHHHHH CS
   Epimerase 138 pnspYaaaKlageklveayaa 158
                 p  +Y ++K+a   l+  + +
  EEA19264.1 148 PAAAYKVTKAALNMLTVVWSQ 168
                 677899999999888877765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (244 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       481  (0.026828); expected 358.6 (0.02)
Passed bias filter:                      470  (0.0262145); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.53u 0.33s 00:00:00.86 Elapsed: 00:00:00.53
# Mc/sec: 1383.63
//
Query:       EEA19265.1  [L=285]
Description: ATP-binding cassette transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    3.1e-30  105.5   0.0    4.7e-30  104.9   0.0    1.3  1  ABC_tran    ABC transporter
    0.00013   21.9   0.8       0.24   11.2   0.1    2.2  2  AAA_21      AAA domain, putative AbiEii toxin, Type IV TA sys
    0.00067   19.2   3.4      0.014   14.8   3.4    2.1  1  SMC_N       RecF/RecN/SMC N terminal domain
  ------ inclusion threshold ------
      0.011   16.0   0.2      0.039   14.2   0.2    1.8  1  AAA_22      AAA domain
      0.016   15.3   0.4      0.053   13.6   0.1    1.9  2  DUF87       Helicase HerA, central domain
      0.032   14.0   0.1      0.065   13.0   0.1    1.5  1  AAA_29      P-loop containing region of AAA domain
      0.033   13.0   0.2      0.033   13.0   0.2    1.5  2  ABC_ATPase  Predicted ATPase of the ABC class
       0.04   14.0   0.0      0.093   12.8   0.0    1.7  1  MMR_HSR1    50S ribosome-binding GTPase
       0.14   11.1   0.1       0.22   10.5   0.1    1.2  1  MeaB        Methylmalonyl Co-A mutase-associated GTPase MeaB
       0.14   12.1   0.4        0.3   11.0   0.1    1.6  2  NTPase_1    NTPase
       0.15   12.6   0.0        4.2    7.9   0.0    2.5  2  AAA_18      AAA domain
       0.19   12.2   2.4       0.47   10.9   2.4    1.8  1  AAA_23      AAA domain


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.9   0.0   3.1e-33   4.7e-30       1     137 []      57     207 ..      57     207 .. 0.91

  Alignments for each domain:
  == domain 1  score: 104.9 bits;  conditional E-value: 3.1e-33
                 EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.........HHHTCHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.........xxxxxxxxxxx RF
    ABC_tran   1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren.........esdeeiekals 90 
                 l+++ l++  g++++i G++G+GKS+L+ +++++ + ++G++++dg +l++ +++++r+++ v+pq+p+l ++ +vr+n         ++d +i +al+
  EEA19265.1  57 LRDICLTVASGTRLGICGRTGSGKSSLILAILRMIEIQKGNLTIDGVNLQTCPRHIVRSKVTVIPQDPFLLSDRSVRDNlrgfiaaseNDDLKILDALD 155
                 678999******************************************************************************988777777999999 PP

                 HSTTGG.......TTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                 xxxxxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  91 klglke.......lkdtvvksspssLSgGqkqrvalarallkkpkllllDEpta 137
                 k++l e         dt++  ++  LS Gq+q ++lara++ k+k+lllDE+t+
  EEA19265.1 156 KVQLREyidsfaeGLDTKI--DDLFLSTGQQQLICLARAIIMKRKILLLDEATS 207
                 9999995555544344444..3378***************************96 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.1   0.00016      0.24       3      30 ..      71      95 ..      70     111 .. 0.75
   2 !    9.4   0.0   0.00056      0.83     188     279 ..     131     221 ..     109     236 .. 0.67

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00016
      AAA_21  3 vliGpNgsGKSnLLdaldllarldrdve 30
                ++ G+ gsGKS+L+ a+  +   +  ++
  EEA19265.1 71 GICGRTGSGKSSLILAILRM---IEIQK 95
                589**************888...33333 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.00056
      AAA_21 188 lvrslklveielsdlgegeeliasvderlrergvvflengdgqelparel..SdGtkrllalltallralkkgsllliDEpEngLHP...kllrrll 279
                  vr  ++ +i +s +++ + l a+ +++lre ++  + +g   ++ +++l  S G+++l++l+ a++  +   ++ll+DE  ++ ++   +l+ rl+
  EEA19265.1 131 SVRDNLRGFIAASENDDLKILDALDKVQLRE-YIDSFAEG--LDTKIDDLflSTGQQQLICLARAIIMKR---KILLLDEATSNVNHetdQLMQRLI 221
                 4444445555555555555555555555555.44444444..4455555555***************999...9******98888886665555554 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   3.4   9.3e-06     0.014      28     208 ..      71     246 ..      62     254 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 9.3e-06
                 EEEESTTSSHHHHHHHHHHHCTT.TTTTTTCHCCCCCC--BTTCSSTTEEEEEEEEEETTEE.SSSSSSCEEEEEEEETTSEEEEEETTEEE-HHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  28 aivGpNGSGKsnlldAilFvLGersakklrseklsdlihkskekasvkkaeveitfdnedkk.lkiekeevsisrrvkrkgeseykingkevtkkevse 125
                  i G+ GSGKs+l+ Ail ++  ++  +l    ++ +  +    +++ + +v+++ +++     +  ++++     ++++++ ++     +v+ +e+ +
  EEA19265.1  71 GICGRTGSGKSSLILAILRMIEIQKG-NLT---IDGVNLQ-TCPRHIVRSKVTVIPQDPFLLsDRSVRDNLRGFIAASENDDLKILDALDKVQLREYID 164
                 599**************888887766.444...4444344.6778899999999844433221112233344444444445544444557888899999 PP

                 HHHC...TT-STTCS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC-SCE CS
                 xxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 126 lles...agiskelLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQfivislreemlekadkl 208
                  +++   ++i+   LS G+++L+ la   Ai + +   + llDe  ++  ++  + + +l++++ + + +i +++r + l + d +
  EEA19265.1 165 SFAEgldTKIDDLFLSTGQQQLICLAR--AIIMKR--KILLLDEATSNVNHETDQLMQRLIRTEFSGCTIIAVAHRLKSLIDFDMV 246
                 8875333789999*********99885..455544..5899**********************************98887776655 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.2   2.6e-05     0.039      10     112 ..      72     220 ..      66     235 .. 0.68

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 2.6e-05
      AAA_22  10 vtGesGtGKTtllrrlleqldeeakaee...........erpevv.....fvtlpsst..sskdllrellralglelka.................... 70 
                 ++G +G+GK+ l+  +l+  ++++   +           +    +     +v ++ +   s ++++ +l  ++  + ++                    
  EEA19265.1  72 ICGRTGSGKSSLILAILRMIEIQKGNLTidgvnlqtcprH----IvrskvTVIPQDPFllSDRSVRDNLRGFIAASENDdlkildaldkvqlreyidsf 166
                 9******************976654444999999965440....3345224444444477777777777777777777777789778777777777777 PP

      AAA_22  71 ...erlsseell.ealeqalrarav.....ielliiDEaqh.lr..seealeeL 112
                       + ++l+ ++ +q+l   a+     +++l++DEa   ++  ++++++ L
  EEA19265.1 167 aegLDTKIDDLFlSTGQQQLICLARaiimkRKILLLDEATSnVNheTDQLMQRL 220
                 766444555566666666666666678888889999999776655335555444 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   3.6e-05     0.053      24      47 ..      68      91 ..      54     100 .. 0.82
   2 ?   -1.1   0.0       1.1   1.6e+03     164     181 ..     189     206 ..     139     235 .. 0.53

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 3.6e-05
       DUF87 24 rHlAilgsTGsGKSntvavLleel 47
                 +l+i g+TGsGKS ++  +l+ +
  EEA19265.1 68 TRLGICGRTGSGKSSLILAILRMI 91
                689*************99999866 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 1.1
       DUF87 164 aiarlldkledllrkggs 181
                 +++++++k++ ll+++++
  EEA19265.1 189 LARAIIMKRKILLLDEAT 206
                 334444444444444444 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.1   4.4e-05     0.065      25      43 ..      70      88 ..      58      95 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 4.4e-05
      AAA_29 25 tlltGpsGsGKSTllDAiq 43
                  + G++GsGKS+l+ Ai 
  EEA19265.1 70 LGICGRTGSGKSSLILAIL 88
                4599***********8875 PP

>> ABC_ATPase  Predicted ATPase of the ABC class
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.1       1.8   2.7e+03     250     265 ..      73      88 ..      71     101 .. 0.61
   2 ?   13.0   0.2   2.2e-05     0.033     328     385 ..     184     242 ..     152     251 .. 0.70

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 1.8
                 EE-TTSSHHHHHHHHH CS
  ABC_ATPase 250 vGggfhGKsTLLeAle 265
                  G+   GKs L+ A+ 
  EEA19265.1  73 CGRTGSGKSSLILAIL 88 
                 5666666666666653 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 2.2e-05
                 HHHHHHHHHHHTT-SEEEEEGGGS-HHHH---HHHHHHS-GGG-..-B--HHHCHHHHHH CS
  ABC_ATPase 328 sqAanimealeagakllLiDEDtsAtNlmirDermqelvskeke..pitplvdrvrelyk 385
                  q   +++a+ ++ k+lL+DE ts +N    D++mq+l+  e    +i ++++r+++l++
  EEA19265.1 184 QQLICLARAIIMKRKILLLDEATSNVNHET-DQLMQRLIRTEFSgcTIIAVAHRLKSLID 242
                 4556678999*****************988.********988772245556677777754 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   6.2e-05     0.093       2      22 ..      70      90 ..      69     129 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 6.2e-05
                EEEEESTTSSHHHHHHHHHTS CS
    MMR_HSR1  2 vaivGrpNvGKStLinaltge 22
                 +i Gr+ +GKS+Li a+++ 
  EEA19265.1 70 LGICGRTGSGKSSLILAILRM 90
                699**************9974 PP

>> MeaB  Methylmalonyl Co-A mutase-associated GTPase MeaB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.1   0.00015      0.22      16      51 ..      54      89 ..      45     100 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00015
                HHHHHHHGGG-S-SEEEEEEE-TTSSHHHHHHHHHH CS
        MeaB 16 kellerllakaGraqvvGltGvPGaGkstlvealgl 51
                + +l+ ++ +    +++G+ G  G+Gks l+ a+  
  EEA19265.1 54 QPILRDICLTVASGTRLGICGRTGSGKSSLILAILR 89
                6799999999999*****************987654 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.1    0.0002       0.3       2      41 ..      70     111 ..      69     121 .. 0.78
   2 ?   -2.3   0.0       2.5   3.7e+03      83     131 ..     215     233 ..     191     253 .. 0.63

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.0002
                 EEEE--TTSSHHHHHHHHHHHH.....GGGEEEEEEEEE--- CS
    NTPase_1   2 vfiTGppGvGKtTlvkkvlell..kssgvkvgGfyteevreg 41 
                 + i G+ G+GK+ l+  +l+++  ++ +++++G+  +   ++
  EEA19265.1  70 LGICGRTGSGKSSLILAILRMIeiQKGNLTIDGVNLQTCPRH 111
                 6799***************9872256699****987776655 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 2.5
                 HHHHHHHHHHHHHH-EEEE---STTGGG-HHHHHHHHHHHTTTSEEEEE CS
    NTPase_1  83 elalealrkalseadviviDEiGkmElkskkfkeaveevLksekpvlav 131
                 +l+ + +r+++s++ +i                              av
  EEA19265.1 215 QLMQRLIRTEFSGCTII------------------------------AV 233
                 44444444444444333..............................33 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0      0.12   1.8e+02      50     106 ..      12      69 ..       2      71 .. 0.76
   2 ?    7.9   0.0    0.0028       4.2       2      44 ..      71     125 ..      70     220 .. 0.72

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.12
      AAA_18  50 krldedkldklldaleenss.aleegknlvidghlaeleseaakdikkvvLtaspeel 106
                 +r+++d+  ++l   ++++s a+ +++ +v+d++ a +   ++ ++  ++Lt+   ++
  EEA19265.1  12 RRFQKDVSSENLPSEDQIPSsAWPSEGQVVFDDISAGYSLIDQPILRDICLTVASGTR 69 
                 55555565566666666666899999999********998888887779999987776 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0028
      AAA_18   2 lltGtpGvGKttlakeLskrlgf............gvnlrdvakenglllevdpe 44 
                 +++G  G+GK++l  ++ ++ ++             +  r++++ + +++++dp+
  EEA19265.1  71 GICGRTGSGKSSLILAILRMIEIqkgnltidgvnlQTCPRHIVRSKVTVIPQDPF 125
                 59************99988866677667777333333334566666666666666 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   2.4   0.00031      0.47      24      39 ..      72      87 ..      70     238 .. 0.95

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00031
      AAA_23 24 ItGpNGaGKTTildAi 39
                I+G +G+GK++++ Ai
  EEA19265.1 72 ICGRTGSGKSSLILAI 87
                9************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (285 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       454  (0.0253221); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        69  (0.00384851); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.51u 0.33s 00:00:00.84 Elapsed: 00:00:00.48
# Mc/sec: 1767.96
//
Query:       EEA19266.1  [L=1061]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.9e-26   91.1  25.6    3.4e-18   66.3   7.9    3.1  3  ABC_membrane  ABC transporter transmembrane region
    4.8e-17   62.8   0.0    1.2e-16   61.5   0.0    1.7  1  ABC_tran      ABC transporter
    1.5e-05   24.5   0.0      0.014   14.9   0.0    2.3  2  SMC_N         RecF/RecN/SMC N terminal domain
    3.8e-05   23.3   0.1    0.00014   21.5   0.0    1.9  2  AAA_29        P-loop containing region of AAA domain
    0.00069   19.5   0.0     0.0014   18.5   0.0    1.6  1  AAA_21        AAA domain, putative AbiEii toxin, Type IV TA s
     0.0031   16.6   0.2     0.0065   15.6   0.2    1.4  1  T2SSE         Type II/IV secretion system protein
     0.0035   17.6   0.1      0.014   15.7   0.0    2.0  2  AAA_22        AAA domain
     0.0049   15.7   0.5        1.2    7.9   0.1    2.2  2  ABC_ATPase    Predicted ATPase of the ABC class
  ------ inclusion threshold ------
      0.025   15.1   0.1      0.049   14.1   0.1    1.4  1  AAA_23        AAA domain
      0.027   14.8   0.0      0.062   13.7   0.0    1.6  1  AAA_16        AAA ATPase domain
      0.032   14.1   0.1      0.064   13.2   0.1    1.4  1  RsgA_GTPase   RsgA GTPase
       0.06   13.4   0.0       0.12   12.5   0.0    1.4  1  Dynamin_N     Dynamin family
      0.089   12.4   0.2       0.17   11.5   0.2    1.4  1  cobW          CobW/HypB/UreG, nucleotide-binding domain
       0.13   11.8   0.1       0.34   10.5   0.1    1.6  1  AAA_25        AAA domain
       0.16   11.6   0.1       0.29   10.8   0.1    1.3  1  AAA_15        AAA ATPase domain


Domain annotation for each model (and alignments):
>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.1   7.7   1.5e-10   1.7e-07       2     212 ..     212     417 ..     211     479 .. 0.87
   2 ?   -0.9   0.5      0.86     1e+03     222     271 ..     453     500 ..     440     505 .. 0.64
   3 !   66.3   7.9   2.8e-21   3.4e-18       1     199 [.     866    1061 .]     866    1061 .] 0.94

  Alignments for each domain:
  == domain 1  score: 31.1 bits;  conditional E-value: 1.5e-10
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHHHHSCHH CS
  ABC_membrane   2 iliillailagvlsplfplvlgrildtlldkgdpetealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsffdtnsvG 98 
                   ++++++ ++  +l+  +p++++r+++ + dk++++  +   ++  ++l++++ ++++ l+++ +     +++ ++ +++++k l+   +  ++ ++ 
    EEA19266.1 212 LYSFMARLALIGLNYSQPFLISRLINYVGDKSSNRN-DGYGLIGGFALVFILKAVFNGLYQHHNFRFITQIRGAIVSMIYEKTLEVRYKTDSNLPAA 307
                   68899999999*******************987777.8************************************************99999999999 PP

                   HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHH CS
  ABC_membrane  99 ellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirtVka 195
                   +l   + n+v++++ g+++ + ++  ++ + ++++++ + + w  + +  ai++ +++++ +i++++ k +   +k v ++ +++   l+ i++Vk 
    EEA19266.1 308 TL---MGNEVDNISIGIQNAHETWASPIELGIAIYLLEIEVHWA-AAIPAAISLAVFYMTGLISRTFPKRQAAWMKGVHQRVAFTSNYLNIIKVVKM 400
                   88...9*************************************6.89999*********************************************** PP

                   TTTHHHHHHHHHHHHHH CS
  ABC_membrane 196 fgreeyflekfekalee 212
                   +g  e+     ++ +  
    EEA19266.1 401 LGLLERISAIVQELRVH 417
                   *9988766655555544 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.86
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSTHHHHHHHHHHHHHHH CS
  ABC_membrane 222 ianglligitqllgllsyalalwfGttlvisgelsvgdlvvflslfailf 271
                   i++ +++gi+  l+ ++++ ++  +++   ++ l+v +  +f++l+ il+
    EEA19266.1 453 ILTTIISGISSNLTPVITLSVYTGAAFCTGRNPLTVAQ--TFMALSIILL 500
                   45556666666666666666644445555668889999..6666665554 PP

  == domain 3  score: 66.3 bits;  conditional E-value: 2.8e-21
                    HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHHHHHHHHHCSTHHHHHH CS
  ABC_membrane    1 liliillailagvlsplfplvlgrildtlldkgdpetealnvysllllllglaqfilallqsyll.nvtgerlskrlrrklfkkilrqpmsffdt 94  
                    ++l++++++l+ ++s + +l+ + + d+    +  +   l+ y+ ++++l+++ ++l+ l  +l+ + +  + s+  +  l+ k+  +p+sf  +
    EEA19266.1  866 VLLCFFCLFLGAFCSQFPSLWVQWWADDNAR-SPFRH--LATYISVYFVLAIMGSVLWALCMWLIfCSIVPKSSSLFHEHLVTKVKDAPLSFLTS 957 
                    5899*************************87.77777..999***********999999999988688*************************** PP

                    SCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT CS
  ABC_membrane   95 nsvGellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsg 189 
                    ++ G +l+r++ d+  ++ +l+  + l + ++++++++ +++ +   +++ ++ +  ++++l+++++ +++++l++ + ++ + +++ ++E++ g
    EEA19266.1  958 THNGIILNRFSQDMTLVDRSLPADF-LKTNNFMQCLMSALFISVKAKYFAPLIAIAGFVVYLIQKFYLRTSRQLRQLDLETKSSLYTQFTETIIG 1051
                    *********************9986.5678888888888888888888*********************************************** PP

                    HHHHHHTTTH CS
  ABC_membrane  190 irtVkafgre 199 
                    + t++afg++
    EEA19266.1 1052 LTTIRAFGWQ 1061
                    *********8 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.5   0.0   9.8e-20   1.2e-16       1     134 [.     604     738 ..     604     741 .. 0.75

  Alignments for each domain:
  == domain 1  score: 61.5 bits;  conditional E-value: 9.8e-20
                 EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEET.TCEGGG.B-HHHCCHCEEEE-SS--S-TTSBHHHH...............HHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxx...............xxx RF
    ABC_tran   1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilld.gkdlke.qeleslrkeigvlpqepqlfpeltvren...............esd 82 
                 l+++s+kl +g+ + ++G+ G+GKStLl++++g+l  t+G i+++ +  ++  +              +p +  ++ +re+                + 
  EEA19266.1 604 LSKISIKLPRGSFTMVIGPVGSGKSTLLQAILGELYCTKGYIQIQpSLTVSFcD-------------TNPWIRHKT-IRETilgslnydeilyqtvIQA 688
                 6789**************************************887333333342.............332222222.3333333333333332224677 PP

                 TCHHHHHHHSTTGGTTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEES CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  83 eeiekalsklglkelkdtvvksspssLSgGqkqrvalarallkkpkllllDE 134
                   +e+ ++++ + +   t+++s++  +SgGq+qr+a+ara+ ++++l l+D+
  EEA19266.1 689 CALEADIKTFPQGH--FTPLGSNGIAISGGQRQRIAIARAVYSRAQLALFDD 738
                 77888889999888..7899999****************************8 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   1.2e-05     0.014      24      48 ..     614     635 ..     603     642 .. 0.84
   2 !    7.1   0.0    0.0027       3.2     136     181 ..     712     753 ..     659     759 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.2e-05
                 SSEEEEEESTTSSHHHHHHHHHHHC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  24 ksftaivGpNGSGKsnlldAilFvL 48 
                  sft+++Gp GSGKs ll+Ai   L
  EEA19266.1 614 GSFTMVIGPVGSGKSTLLQAI---L 635
                 57*******************...4 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0027
                 CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 136 lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvae 181
                 ++SgG+++ +a+a       +++a l l+D++ +aLD++  + v++
  EEA19266.1 712 AISGGQRQRIAIA----RAVYSRAQLALFDDVLSALDARTYEHVST 753
                 5899999987765....55799999*************99998875 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.0   1.2e-07   0.00014      17      49 ..     609     641 ..     597     646 .. 0.81
   2 ?   -2.6   0.0       3.9   4.6e+03       5      33 ..     785     815 ..     782     815 .. 0.62

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 1.2e-07
      AAA_29  17 ieidlkg.atlltGpsGsGKSTllDAiqalLvpa 49 
                 i++  +g +t+++Gp GsGKSTll Ai   L+++
  EEA19266.1 609 IKLP-RGsFTMVIGPVGSGKSTLLQAILGELYCT 641
                 5555.4569*****************98777766 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 3.9
      AAA_29   5 qlvNWgtfdghtieidlkg..atlltGpsGs 33 
                  +++ g +++h+++ +     + ll+G++ s
  EEA19266.1 785 VVLEEGMISQHSHPREIVAnkNSLLAGDTSS 815
                 5666777777655544322248999999876 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.0   1.2e-06    0.0014       1      20 [.     616     635 ..     616     663 .. 0.88

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 1.2e-06
      AAA_21   1 lnvliGpNgsGKSnLLdald 20 
                 ++++iGp gsGKS+LL+a+ 
  EEA19266.1 616 FTMVIGPVGSGKSTLLQAIL 635
                 79****************94 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.2   5.4e-06    0.0065      90     154 ..     573     639 ..     550     647 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 5.4e-06
       T2SSE  90 gealviR..kksakeltlddlgaeealkekiaevlrkavrerglilvsGgTgsGKttllyallkein 154
                 g + +iR  ++++  + +++  ++ +l+++i + ++  + +    +v G+ gsGK+tll a+l e+ 
  EEA19266.1 573 GRKSTIRqaSQTTDVVVIQEADFSWNLTQAILSKISIKLPRGSFTMVIGPVGSGKSTLLQAILGELY 639
                 4778999766677778999999999999999999999988888999*****************9986 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       3.9   4.7e+03      91     102 ..     578     595 ..     540     608 .. 0.68
   2 !   15.7   0.0   1.2e-05     0.014       5      29 ..     614     638 ..     611     689 .. 0.69

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 3.9
      AAA_22  91 v......ielliiDEaqh 102
                        + +++i Ea++
  EEA19266.1 578 IrqasqtTDVVVIQEADF 595
                 122334456799999986 PP

  == domain 2  score: 15.7 bits;  conditional E-value: 1.2e-05
      AAA_22   5 agilvvtGesGtGKTtllrrlleql 29 
                  ++++v+G++G+GK+tll+ +l +l
  EEA19266.1 614 GSFTMVIGPVGSGKSTLLQAILGEL 638
                 6899***************998776 PP

>> ABC_ATPase  Predicted ATPase of the ABC class
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.9   0.1   0.00099       1.2     242     265 ..     611     635 ..     600     640 .. 0.89
   2 !    5.8   0.0    0.0041       4.9     357     420 ..     735     796 ..     714     818 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.00099
                 E-SS.EEEEEE-TTSSHHHHHHHHH CS
  ABC_ATPase 242 ipkG.vtlIvGggfhGKsTLLeAle 265
                 +p+G  t+++G+   GKsTLL+A+ 
  EEA19266.1 611 LPRGsFTMVIGPVGSGKSTLLQAIL 635
                 799999*****************95 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0041
                 ---HHHHHHS-GGG--B--HHHCHHHHHHHH--EEEEEESS-GCCTTT-SEEEEEETTEEEE-H CS
  ABC_ATPase 357 irDermqelvskekepitplvdrvrelykklgvstilvvggsgdyldvAdtvilmeeykpkdvt 420
                 + D+ +++l +++ e + + v  ++ l +++gv+++ v+ +++  l++Ad+++++ee  +++ +
  EEA19266.1 735 LFDDVLSALDARTYEHVSTNVFGIQGLLRRNGVTVVFVAHALD--LNSADQIVVLEEGMISQHS 796
                 56999999******************************98887..79********997777766 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.1   4.1e-05     0.049      20      44 ..     615     639 ..     602     651 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 4.1e-05
      AAA_23  20 gltlItGpNGaGKTTildAiklaLy 44 
                  +t ++Gp G+GK+T+l+Ai   Ly
  EEA19266.1 615 SFTMVIGPVGSGKSTLLQAILGELY 639
                 58999***************86666 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   5.2e-05     0.062      21      48 ..     611     638 ..     598     734 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 5.2e-05
      AAA_16  21 sgrpelvllsGesGvGKsslvrellral 48 
                  +r++ ++++G+ G+GKs+l++++l +l
  EEA19266.1 611 LPRGSFTMVIGPVGSGKSTLLQAILGEL 638
                 4556899***************999544 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.1   5.4e-05     0.064      86     124 ..     600     639 ..     564     650 .. 0.75

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 5.4e-05
                  THTTHHHHHHHCTT.SEEEEECSTTSSHHHHHHHHCTT-- CS
  RsgA_GTPase  86 tkegleelkellkd.ktsvlvGqSGvGKStLinallpele 124
                  t++ l++++ +l   ++++++G+ G GKStL+ a+l+el 
   EEA19266.1 600 TQAILSKISIKLPRgSFTMVIGPVGSGKSTLLQAILGELY 639
                  45567778777766699******************99865 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   9.7e-05      0.12       2      22 ..     618     638 ..     617     651 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 9.7e-05
                 EEEEBTTTTHHHHHHHHHTS- CS
   Dynamin_N   2 avvGsqSsGKSSvlnaLlged 22 
                 +v+G + sGKS++l a+lge 
  EEA19266.1 618 MVIGPVGSGKSTLLQAILGEL 638
                 69*****************86 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.2   0.00014      0.17       3      21 ..     617     635 ..     615     645 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00014
                 EEEEESTTCCHHHHHHHHH CS
        cobW   3 tvltGflGsGKTtLlnhll 21 
                 t++ G++GsGK+tLl+++l
  EEA19266.1 617 TMVIGPVGSGKSTLLQAIL 635
                 7899************998 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.1   0.00028      0.34      30      52 ..     611     633 ..     605     642 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00028
      AAA_25  30 lpagelallaGapgtGKttlald 52 
                 lp+g++++++G+ g+GK+tl+  
  EEA19266.1 611 LPRGSFTMVIGPVGSGKSTLLQA 633
                 79******************865 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.1   0.00025      0.29      15      43 ..     605     634 ..     603     639 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00025
      AAA_15  15 kdveidlsee.ltvliGkNnsGKSsileal 43 
                 ++++i+l    +t +iG+ +sGKS++l+a+
  EEA19266.1 605 SKISIKLPRGsFTMVIGPVGSGKSTLLQAI 634
                 56677776667******************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1061 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       930  (0.0518713); expected 358.6 (0.02)
Passed bias filter:                      571  (0.0318478); expected 358.6 (0.02)
Passed Vit filter:                        82  (0.0045736); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.90u 0.33s 00:00:01.23 Elapsed: 00:00:00.51
# Mc/sec: 6273.72
//
Query:       EEA19267.1  [L=616]
Description: hypothetical protein PMAA_015250 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.6e-16   58.0   0.2    1.2e-15   57.4   0.2    1.3  1  Retrotran_gag_2  gag-polypeptide of LTR copia-type
    2.2e-10   39.9   0.2    4.9e-10   38.8   0.2    1.6  1  DUF4219          Domain of unknown function (DUF4219)
    3.9e-06   26.7   1.7    3.9e-06   26.7   1.7    1.9  2  zf-CCHC          Zinc knuckle
  ------ inclusion threshold ------
      0.025   14.4   1.3      0.055   13.3   1.3    1.5  1  zf-CCHC_6        Zinc knuckle
      0.032   14.4   1.2      0.074   13.2   0.3    2.1  2  CAF1A            Chromatin assembly factor 1 subunit A
       0.15   11.9   1.9        1.1    9.0   0.3    2.5  2  zf-CCHC_4        Zinc knuckle
       0.15   12.5   0.0       0.59   10.6   0.0    2.0  1  zf-C2HE          C2HE / C2H2 / C2HC zinc-binding finger
       0.41   10.6   4.1         50    3.9   0.1    3.6  3  ADH_N_assoc      Alcohol dehydrogenase GroES-associated
       0.62    9.9   2.7        1.5    8.7   2.7    1.6  1  HscB_4_cys       Co-chaperone HscB tetracysteine metal bindin
        5.4    7.3   8.3          2    8.7   0.4    2.9  2  DUF3035          Protein of unknown function (DUF3035)
        9.6    6.1   7.4       0.29   11.0   1.2    1.7  2  zf-CCHC_2        Zinc knuckle


Domain annotation for each model (and alignments):
>> Retrotran_gag_2  gag-polypeptide of LTR copia-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.4   0.2   7.4e-19   1.2e-15       1     132 [.      83     216 ..      83     222 .. 0.95

  Alignments for each domain:
  == domain 1  score: 57.4 bits;  conditional E-value: 7.4e-19
  Retrotran_gag_2   1 wkkkdakalalIvlsisdsllelvkeektakevWdkLkelyekksaankltlrkklfslkmkegesvadhinkleelvneLsalgv...kidde 91 
                      wk+ + +a+ +I+  i+++ +  v+++k + e+W  + + ye+k+    ++ +++ ++ k++ + s++d +++le+l  eL+++ +   k+ + 
       EEA19267.1  83 WKSANGRAKLYILGNIKQDDISTVRDCKLSGEMWAYIRKKYERKTHVDIMMAIQRIVDWKKSAEASMEDSLQQLEQLEAELRDVSDgqiKLGEL 176
                      99999*****************************************************************************975544599999 PP

  Retrotran_gag_2  92 dkvvllLasLPesyetfvtaiesseedltleevieklleee 132
                      +++   L+ LP++yet++ ai+  +e++t e+v ++l+ +e
       EEA19267.1 177 MILNFFLRGLPKDYETITYAIMG-SETITRENVLSRLQVQE 216
                      9********************88.9************9877 PP

>> DUF4219  Domain of unknown function (DUF4219)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.8   0.2     3e-13   4.9e-10       3      27 .]      38      62 ..      36      62 .. 0.95

  Alignments for each domain:
  == domain 1  score: 38.8 bits;  conditional E-value: 3e-13
     DUF4219  3 gtNYatWklrMklyLiaqdLWevVe 27
                ++N ++WklrM+ +L++qd+W++Ve
  EEA19267.1 38 RSNIKNWKLRMQIFLEIQDCWDMVE 62
                69**********************8 PP

>> zf-CCHC  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.1       8.2   1.3e+04      14      17 ..     107     110 ..     106     110 .. 0.82
   2 !   26.7   1.7   2.4e-09   3.9e-06       2      18 .]     236     252 ..     235     252 .. 0.95

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 8.2
                 TTST CS
     zf-CCHC  14 rdCp 17 
                 rdC+
  EEA19267.1 107 RDCK 110
                 9**6 PP

  == domain 2  score: 26.7 bits;  conditional E-value: 2.4e-09
                 CTSSSSSSSSTTTTSTS CS
     zf-CCHC   2 kCynCGepGHiardCpk 18 
                 kC+nCG++GH+ ++Cp+
  EEA19267.1 236 KCWNCGKEGHRMSECPE 252
                 8***************6 PP

>> zf-CCHC_6  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   1.3   3.4e-05     0.055       2      20 ..     235     251 ..     234     257 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 3.4e-05
   zf-CCHC_6   2 vKCknCGAFGHtarSkrCP 20 
                 +KC+nCG  GH++  + CP
  EEA19267.1 235 LKCWNCGKEGHRM--SECP 251
                 7***********9..7898 PP

>> CAF1A  Chromatin assembly factor 1 subunit A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.3   4.6e-05     0.074      18      59 ..     291     331 ..     282     344 .. 0.79
   2 ?   -3.8   0.0       9.2   1.5e+04      10      20 ..     587     597 ..     584     599 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 4.6e-05
       CAF1A  18 tkkskvvgarnPfskdekeldYdyDSdaEWeeeeeeegedle 59 
                 + k++v g ++P + +  + dYd DSda    e +++ge   
  EEA19267.1 291 KDKTQVKGKKKPYRGSARKADYDSDSDAGSTTE-DSDGERAA 331
                 567788889********************9775.55898755 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 9.2
       CAF1A  10 RPpYyGTwtkk 20 
                 R  Y+GT +++
  EEA19267.1 587 RTSYLGTRSNQ 597
                 789****8865 PP

>> zf-CCHC_4  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.1      0.17   2.8e+02      13      29 ..     109     125 ..     103     127 .. 0.83
   2 ?    9.0   0.3   0.00069       1.1      30      48 ..     232     251 ..     230     252 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.17
   zf-CCHC_4  13 ikkesGeeatiefkYEr 29 
                  k+ +  +a i+ kYEr
  EEA19267.1 109 CKLSGEMWAYIRKKYER 125
                 5666779*********9 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00069
   zf-CCHC_4  30 Lrsf.CyiCgvlGHsdkrCd 48 
                 +r + C +Cg  GH +++C+
  EEA19267.1 232 IRGLkCWNCGKEGHRMSECP 251
                 56666**************8 PP

>> zf-C2HE  C2HE / C2H2 / C2HC zinc-binding finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00036      0.59      10      52 ..     207     248 ..     203     249 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00036
     zf-C2HE  10 dlpeelekdgeieslseeqskelilktpLkCtrCganfgnkfp 52 
                 +++++l++++ i   +e+  ++ ++ + LkC+ Cg ++g  + 
  EEA19267.1 207 NVLSRLQVQEGILGQKEKVIESANRIRGLKCWNCG-KEGHRMS 248
                 566667766666445788889999999********.9999886 PP

>> ADH_N_assoc  Alcohol dehydrogenase GroES-associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.11   1.8e+02       7      16 ..     348     357 ..     348     357 .. 0.92
   2 ?    3.9   0.1     0.031        50       7      16 ..     395     404 ..     395     404 .. 0.92
   3 ?    3.9   0.1     0.031        50       7      16 ..     442     451 ..     442     451 .. 0.92

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.11
  ADH_N_assoc   7 qGpkdVrVee 16 
                  +G++d+r ee
   EEA19267.1 348 NGKRDIRIEE 357
                  6*******98 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.031
  ADH_N_assoc   7 qGpkdVrVee 16 
                  +G++dVr ee
   EEA19267.1 395 NGKRDVRIEE 404
                  6*******98 PP

  == domain 3  score: 3.9 bits;  conditional E-value: 0.031
  ADH_N_assoc   7 qGpkdVrVee 16 
                  +G++dVr ee
   EEA19267.1 442 NGKRDVRIEE 451
                  6*******98 PP

>> HscB_4_cys  Co-chaperone HscB tetracysteine metal binding motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   2.7   0.00091       1.5       2      13 ..     236     247 ..     236     252 .. 0.82

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00091
                 B-SSS--B--SS CS
  HscB_4_cys   2 rCWnCGgpgapg 13 
                 +CWnCG+ g  +
  EEA19267.1 236 KCWNCGKEGHRM 247
                 6*****998766 PP

>> DUF3035  Protein of unknown function (DUF3035)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.4    0.0012         2      32      92 ..     300     359 ..     294     367 .. 0.85
   2 ?    0.1   2.9      0.55     9e+02      49      93 ..     411     454 ..     357     485 .. 0.65

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0012
     DUF3035  32 paPtpGaarpqdetpraeavaaLgGnpsaalkaksglsagekaLlkqagrdgvdpniRetl 92 
                 ++P  G ar +d +++ +a +++  +  + ++  + +s+ e+aL+++++  ++d +i e+l
  EEA19267.1 300 KKPYRGSARKADYDSDSDAGSTTEDSDGERAARVEMVSPDEQALVARSNG-KRDIRIEESL 359
                 689********************88888777789**************97.6666666665 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.55
     DUF3035  49 eavaaLgGnpsaalkaksglsagekaLlkqagrdgvdpniRetla 93 
                  a ++L+++ +  ++     ++ e+aL+++++  ++d +i e+l+
  EEA19267.1 411 VAKQVLVEKSDGQQAVRIRQESLEQALVARSNG-KRDVRIEESLE 454
                 344555555444444566666677777777775.67777777764 PP

>> zf-CCHC_2  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.6       6.4     1e+04      16      19 ..      54      57 ..      54      57 .. 0.96
   2 ?   11.0   1.2   0.00018      0.29       5      21 .]     236     252 ..     234     252 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 6.4
   zf-CCHC_2 16 IqdC 19
                IqdC
  EEA19267.1 54 IQDC 57
                9*** PP

  == domain 2  score: 11.0 bits;  conditional E-value: 0.00018
   zf-CCHC_2   5 vChiCgkkGHyIqdCPt 21 
                 +C  Cgk GH  ++CP+
  EEA19267.1 236 KCWNCGKEGHRMSECPE 252
                 6889************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (616 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1044  (0.0582297); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.60u 0.31s 00:00:00.90 Elapsed: 00:00:00.47
# Mc/sec: 3958.03
//
Query:       EEA19268.1  [L=586]
Description: hypothetical protein PMAA_015260 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-38  132.2   0.1    2.2e-19   70.0   0.0    2.2  2  RVT_2     Reverse transcriptase (RNA-dependent DNA polymerase
  ------ inclusion threshold ------
      0.013   15.0   0.0      0.027   14.0   0.0    1.5  1  RVT_1     Reverse transcriptase (RNA-dependent DNA polymerase
      0.018   15.2   2.0      0.028   14.5   2.0    1.3  1  YL1       YL1 nuclear protein
      0.033   13.8   0.0      0.061   13.0   0.0    1.4  1  Crr6      Chlororespiratory reduction 6


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.9   0.0   3.1e-20   1.4e-16       6      72 ..     256     323 ..     252     325 .. 0.89
   2 !   70.0   0.0     5e-23   2.2e-19     122     237 ..     324     436 ..     322     440 .. 0.95

  Alignments for each domain:
  == domain 1  score: 60.9 bits;  conditional E-value: 3.1e-20
       RVT_2   6 vslPkdrkaigsrWvftkkkddl.kevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaae 72 
                 v+   ++  i+ +Wvf +k ++  +  ++karlva+Gfsq+ g d++++faPvirl+s+r+l a+a++
  EEA19268.1 256 VKRLDHKAVISCKWVFDIKYQADgRIERFKARLVARGFSQQEGLDFEDTFAPVIRLESLRVLFAIAVM 323
                 555566667999*******988768899**************************************86 PP

  == domain 2  score: 70.0 bits;  conditional E-value: 5e-23
       RVT_2 122 lkqapllWnekidkvLkklgferseaesGlyvrgtgegklivalyvddlliagsdikiledvkkelakkfklkdlgkvskfLGieiaqeaggiklslad 220
                 l+q++ lW +k++k+++ +gf++s+a  G ++        i+aly+dd+l+ +++ k +e  k++l++ + +kd g+v+k LGi i+   g i+l ++ 
  EEA19268.1 324 LRQSANLWCHKVKKFVTSIGFKPSTADPGAFINER---GTIIALYMDDILVFSKNEKAIELTKEKLKEFHPMKDSGRVNKILGIRITWLDGSIRLDQEF 419
                 89******************************984...369********************************************************** PP

       RVT_2 221 yiakvvkkfeltdaktv 237
                 y  +++++f++ ++k++
  EEA19268.1 420 YTIRILEEFDMLESKPQ 436
                 ***********998865 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   6.1e-06     0.027     159     190 ..     358     389 ..     323     394 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 6.1e-06
                 ...TEEECTTEEEEEESSHHHHHHHHHHHHHH CS
       RVT_1 159 kgvtllrYaDDililskskeelqelleaveew 190
                  g  +++Y+DDil++sk++++++   e+++e+
  EEA19268.1 358 RGTIIALYMDDILVFSKNEKAIELTKEKLKEF 389
                 48899**************9988777777765 PP

>> YL1  YL1 nuclear protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   2.0   6.3e-06     0.028     126     199 ..     175     248 ..      86     256 .. 0.70

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 6.3e-06
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         YL1 126 eraswlpaeslltpkrRkssRastven..keqleerlkereerrkkilermrkkaarkkkkkkerplTQeerLaeA 199
                 e    +++es+l+p+  +  R+  v++  ++ le+   e+  rrk+++ r +++ +  k  + +  lTQe rL+e 
  EEA19268.1 175 ESI-SIESESTLAPT-TTLRRTDRVRKptQAVLESAATEAIYRRKSQQGRRQEAWEASKDTTSRTSLTQEARLQEV 248
                 333.34444445555.455555555555244455566666888899998888888888888889*********995 PP

>> Crr6  Chlororespiratory reduction 6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   1.4e-05     0.061      49     141 ..     244     344 ..     199     348 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 1.4e-05
        Crr6  49 ElsEipevRlwfi.rldav....yPwlpllldwkaGelaryaamlvpHqfsrkeGiqfnpea...leifvmkkvfvladwlkkqgiesksrlkslaqll 139
                  l E++++ + f+ rld      + w+  +  + +G++ r+ a lv   fs++eG+ f+      + +   + +f +a +l+++     +++k++   +
  EEA19268.1 244 RLQEVANLAVRFVkRLDHKavisCKWVFDIKYQADGRIERFKARLVARGFSQQEGLDFEDTFapvIRLESLRVLFAIAVMLRQSANLWCHKVKKFVTSI 342
                 46666666666664566431122456666666789***********************97641113333445567777788887777788888888888 PP

        Crr6 140 Gy 141
                 G+
  EEA19268.1 343 GF 344
                 88 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (586 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       582  (0.0324614); expected 358.6 (0.02)
Passed bias filter:                      402  (0.0224218); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.31s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 3884.13
//
Query:       EEA19269.1  [L=1142]
Description: DNA helicase recq, putative, partial [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.9e-12   47.0   9.6    2.9e-12   47.0   9.6    2.4  2  OrsD          Orsellinic acid/F9775 biosynthesis cluster prot
    3.4e-11   43.2   0.0    1.1e-10   41.5   0.0    1.8  1  DEAD          DEAD/DEAH box helicase
    0.00054   20.0   0.0     0.0014   18.7   0.0    1.7  1  ResIII        Type III restriction enzyme, res subunit
  ------ inclusion threshold ------
      0.097   11.9   0.0       0.16   11.2   0.0    1.3  1  Peptidase_S8  Subtilase family
        1.8    8.2   8.7       0.14   11.8   3.0    2.2  2  zf-C2H2_12    Zinc-finger C2H2-type


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.0   9.6   8.2e-16   2.9e-12       1     114 []       8     118 ..       8     118 .. 0.86
   2 ?   -1.5   0.0      0.95   3.4e+03      35      63 ..     504     531 ..     495     545 .. 0.71

  Alignments for each domain:
  == domain 1  score: 47.0 bits;  conditional E-value: 8.2e-16
        OrsD   1 dlfeyneeyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgL..pvyeGyrCrakakCky 97 
                 ++f+y++++r++iC  C++ v  s+l +HLr+  +  +    ++ ++ +  ++  +q+ e  r++ ++ +p+++ +pipgL  p    y+C   ++C++
  EEA19269.1   8 QIFQYDPHHRIVICCLCQHVVFDSQLPSHLRNTRHIRE----RHSQHIILFQQYHQQFPERIRHHRELVIPHKPIAPIPGLipPRDPTYQC-SYPGCHW 101
                 57*****************************5544443....34556665557788999999******************96555699***.78***** PP

        OrsD  98 ltrslktlrkHlqkkhg 114
                 +  +++++++H +++hg
  EEA19269.1 102 IGETIRRIHDHCRQEHG 118
                 **************995 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.95
        OrsD  35 rqlkrektqelletvehemslrqldelar 63 
                  q++r ++ +l+etv h    r +d+l++
  EEA19269.1 504 YQHHRFTMDQLRETV-HGIINRAWDHLTQ 531
                 456666788999999.8888899996644 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.5   0.0   3.2e-14   1.1e-10       3     173 ..     904    1054 ..     902    1058 .. 0.77

  Alignments for each domain:
  == domain 1  score: 41.5 bits;  conditional E-value: 3.2e-14
                  HHHHHHHHHHTTC.EEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTC CS
                  xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD    3 iQaeaiplilggg.dvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngv 98  
                  iQ++ai++++g    vl+ + TG GK+++f++p+    +    +++   ++v+Pt +L +++ +++ + +      ++ + +  +         +++
  EEA19269.1  904 IQKAAIDAVMGSApWVLGVMGTGGGKSMIFMVPAA---W----ERAGTSIVVVPTVSLRQDMQRECAQAGIS----CVPWNSHRPP--------ETA 981 
                  9*********66559********************...4....456689*******************9994....2222222222........456 PP

                  SEEEEEHHHHHHHH.....HCTSSHCTTEEEEEEETHHHHHHT..TTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHH CS
                  xxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   99 divvgtpgrlddll.....stgklnlsqvrflVlDEadrlldq..gfsdfinrilnqlpqitcdgklqrqvivlSATlpkdv 173 
                  +iv+ tp+   +       s +  + +++  +V+DE++++ld+  +f++++  ++  +   t   +    v++l+ATlp  v
  EEA19269.1  982 RIVLVTPESATSKGfrsyiS-RLQERNRLDRIVIDECHTILDSreEFRPKMAGLHVLM---TIGSP----VVLLTATLP-AV 1054
                  78999998888844354432.2223788899***********9888888888877777...44445....********9.44 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   3.9e-07    0.0014      29     147 ..     921    1023 ..     900    1053 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 3.9e-07
                  EEESTTSTHHHHH.HHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--.......-SEEEEEHHHHHHTH...... CS
      ResIII   29 ikmaTGtGKTlva.aklierllkkgkeekflflvprkslleqtleefkkflseaykeigkkvsgdkkkakekdstnkkilvttiqsldadseeeeee 124 
                   +m TG GK+++  + ++++ +        +++vp+ sl + +++e ++   +++      +++ +  +      +++i+++t +s++++   +++ 
  EEA19269.1  921 GVMGTGGGKSMIFmVPAAWERAG-----TSIVVVPTVSLRQDMQRECAQAGISCV-----PWNSHRPPE------TARIVLVTPESATSKG-FRSYI 1000
                  5899******9985677777776.....689********************9875.....677777777......9999999999999988.56999 PP

                  ..HHHTTT-SEEEEETGGGTTS. CS
      ResIII  125 seellrdrfdviiiDEaHrlgak 147 
                  s  ++r+r d i+iDE+H + ++
  EEA19269.1 1001 SRLQERNRLDRIVIDECHTILDS 1023
                  9999**************98875 PP

>> Peptidase_S8  Subtilase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   4.6e-05      0.16      49      88 ..     797     838 ..     708     847 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 4.6e-05
                   S-TT-SC-SSS......HHHHHHHHHH-B..SSSSSB-SSTT CS
                   xxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8  49 tstnwarddngnsie..HGthvAGiaaanapeegekngvapg 88 
                       w++dd + +i+  HG+hvAG++ a   ee      a +
    EEA19269.1 797 DGCWWTADDAVIDIQagHGSHVAGMIYARGVEEAPGTMAAMK 838
                   34447777877777799**********995555555555555 PP

>> zf-C2H2_12  Zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   3.0   3.8e-05      0.14      14      59 ..      10      58 ..       6      64 .. 0.80
   2 ?   -3.8   0.3       2.8     1e+04      37      48 ..     106     117 ..      94     118 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3.8e-05
  zf-C2H2_12 14 mdydpqrrglvCmvCgeslaslkl.stik..rHIrqvHPeslslseeek 59
                  ydp++r ++C  C+++    +l s+++  rHIr++H + + l ++ +
  EEA19269.1 10 FQYDPHHRIVICCLCQHVVFDSQLpSHLRntRHIRERHSQHIILFQQYH 58
                68***************999999844554338******99877766655 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 2.8
  zf-C2H2_12  37 lstikrHIrqvH 48 
                 + +i  H rq H
  EEA19269.1 106 IRRIHDHCRQEH 117
                 678999999999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1142 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       538  (0.0300073); expected 358.6 (0.02)
Passed bias filter:                      389  (0.0216967); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.78u 0.32s 00:00:01.10 Elapsed: 00:00:00.49
# Mc/sec: 6995.01
//
Query:       EEA19270.1  [L=205]
Description: DNA helicase recq, putative, partial [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.2e-14   53.2   0.1    4.6e-14   52.7   0.1    1.2  1  Helicase_C     Helicase conserved C-terminal domain
      0.004   16.4   0.0     0.0054   16.0   0.0    1.1  1  ERCC3_RAD25_C  ERCC3/RAD25/XPB C-terminal helicase


Domain annotation for each model (and alignments):
>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.7   0.1   5.1e-18   4.6e-14      12     110 ..      10     101 ..       2     102 .. 0.89

  Alignments for each domain:
  == domain 1  score: 52.7 bits;  conditional E-value: 5.1e-18
                 HTTTTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSSHHHHHHHHTTSSST CS
  Helicase_C  12 leeeggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprnvtsyiqriGRtgRa 110
                 ++ ++gk++i++nti +++    +   +++++ ++++  ++ +++ +l++f+k++  v++at+++++Gidip+++lVi+++  r++ +y q +GR+gR 
  EEA19270.1  10 QQLHEGKVVIYANTIATVQ---RI--AHQLQCPAYYS--QAVDKKGMLASFQKQNPGVIVATSALGMGIDIPDIRLVIHVGRTRSLLDYGQESGRAGRD 101
                 46689*************5...55..46689999999..89999*******887777*****************************************6 PP

>> ERCC3_RAD25_C  ERCC3/RAD25/XPB C-terminal helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0     6e-07    0.0054      58     147 ..      12     100 ..       2     107 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 6e-07
  ERCC3_RAD25_C  58 krgDkiivfsDnvfaLkeyakklkkpyiyGetseaerlkilqkfkknpkvntiflskvgDtsiDlPeanvliqisshfg..srrqeaqrlGr 147
                     ++ k++++++ + +++++a++l+ p  y ++   +++ +l +f+k++    +  s +g   iD+P+   +i +    +     qe+ r Gr
     EEA19270.1  12 LHEGKVVIYANTIATVQRIAHQLQCPAYYSQA--VDKKGMLASFQKQNPGVIVATSALG-MGIDIPDIRLVIHVGRTRSllDYGQESGRAGR 100
                    4578**********************999765..566789*******999999999999.68**********99765431144566666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (205 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       692  (0.0385967); expected 358.6 (0.02)
Passed bias filter:                      551  (0.0307323); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 1449.49
//
Query:       EEA19271.1  [L=395]
Description: DNA helicase recq, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-11   43.7   0.1    6.6e-11   42.3   0.0    1.7  1  DEAD      DEAD/DEAH box helicase
      3e-05   24.1   0.0    7.7e-05   22.8   0.0    1.7  1  ResIII    Type III restriction enzyme, res subunit


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.3   0.0   7.4e-15   6.6e-11       3     140 ..     245     368 ..     243     372 .. 0.83

  Alignments for each domain:
  == domain 1  score: 42.3 bits;  conditional E-value: 7.4e-15
                 HHHHHHHHHHTTC.EEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTCSE CS
                 xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   3 iQaeaiplilggg.dvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngvdi 100
                  Q+++i+ i++ +  +++ ++TG+GK+l f++p+         ++g  +++v+P+ +L  +  +++++++         +++     d ++ +  g+ i
  EEA19271.1 245 TQKAVIQSIVQRQsPIVAIMPTGAGKSLLFMLPAW-------MSRGGTTIVVVPLVALRADLQQRCQTLGIS-------CVE----WDSRRPV-DGASI 324
                 599*******766378899****************.......4677899************99999999984.......233....4555777.8999* PP

                 EEEEHHHHHHHH.....HCTSSHCTTEEEEEEETHHHHHHTTTHH CS
                 xxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD 101 vvgtpgrlddll.....stgklnlsqvrflVlDEadrlldqgfsd 140
                 v+ tp+  ++ +     + +k  ++++  +V+DE++ +l++g++ 
  EEA19271.1 325 VLVTPESAVSETfqtfiN-RKQWTKELDRIVIDECHIILQEGYQS 368
                 *****9999966465533.343599*****************985 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8   0.0   8.6e-09   7.7e-05       7     146 ..     245     363 ..     213     376 .. 0.81

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 8.6e-09
                 HHHHHHHHHT......TTSEEEEEESTTSTHHHHHHHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--.......-S CS
      ResIII   7 yQeeaienlleklkskrdkrglikmaTGtGKTlvaaklierllkkgkeekflflvprkslleqtleefkkflseaykeigkkvsgdkkkakekdstnkk 105
                  Q+ +i++++     +r+  ++  m+TG+GK+l+ +  ++  +       ++++vp  +l   ++++ + +  +++     ++++++          ++
  EEA19271.1 245 TQKAVIQSIV-----QRQSPIVAIMPTGAGKSLLFMLPAWMSRGG----TTIVVVPLVALRADLQQRCQTLGISCV-----EWDSRRPVD------GAS 323
                 4555555554.....8999**************999999988875....89*********************9874.....566666666......889 PP

                 EEEEEHHHHHHTH........HHHTTT-SEEEEETGGGTTS CS
      ResIII 106 ilvttiqsldadseeeeeeseellrdrfdviiiDEaHrlga 146
                 i+++t +s+ ++   ++  + ++  ++ d i+iDE+H + +
  EEA19271.1 324 IVLVTPESAVSET-FQTFINRKQWTKELDRIVIDECHIILQ 363
                 9999999988888.4456666666777779*******7766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (395 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       625  (0.0348597); expected 358.6 (0.02)
Passed bias filter:                      488  (0.0272185); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.24s 00:00:00.79 Elapsed: 00:00:00.41
# Mc/sec: 2888.78
//
Query:       EEA19272.1  [L=312]
Description: hypothetical protein PMAA_000730 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (312 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       365  (0.0203581); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 2029.05
//
Query:       EEA19273.1  [L=360]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.2e-22   78.2   1.7    7.7e-22   77.9   0.1    2.0  2  OrsD      Orsellinic acid/F9775 biosynthesis cluster protein 


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.9   0.1   4.3e-26   7.7e-22       3     114 .]      12     119 ..      10     119 .. 0.90
   2 ?   -2.7   0.1      0.43   7.8e+03      44      54 ..     132     141 ..     122     161 .. 0.47

  Alignments for each domain:
  == domain 1  score: 77.9 bits;  conditional E-value: 4.3e-26
        OrsD   3 feyneeyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgLpvy.eGyrC.rakakCkylt 99 
                 fe+  ++ v+iCreC+y+v+ps++e HL++ h++++   + +l  +v      r++ ++a ++ ++++p++  + ip+L    +G +C   +++C y++
  EEA19273.1  12 FERLVDFPVVICRECQYGVWPSQIEGHLQRAHQHISPIIRIQLGDEV------RSWPNIAIDPIELEIPPTRTQAIPQLIGPlDGWQCqLSPQSCVYIC 104
                 78888999*********************888777666677777777......*************************98766*****778899***** PP

        OrsD 100 rslktlrkHlqkkhg 114
                 +s++++r+H+ ++hg
  EEA19273.1 105 QSINAMRNHWYNQHG 119
                 ***********9995 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 0.43
        OrsD  44 elletvehems 54 
                 + ++t++ e++
  EEA19273.1 132 STMQTIQ-EQQ 141
                 3333331.111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (360 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       620  (0.0345808); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 2334.90
//
Query:       EEA19274.1  [L=620]
Description: hypothetical protein PMAA_000750 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.021   14.9   0.1      0.092   12.9   0.1    2.0  2  DUF3974   Domain of unknown function (DUF3974)


Domain annotation for each model (and alignments):
>> DUF3974  Domain of unknown function (DUF3974)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0     0.075   1.4e+03      56      85 ..     318     348 ..     306     360 .. 0.72
   2 ?   12.9   0.1   5.1e-06     0.092      40     103 ..     350     408 ..     319     414 .. 0.73

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.075
     DUF3974  56 pflkeftkhplfy.rwirtegkkeqkvlnvl 85 
                  fl   t+ p+ +   +rt gkk q++ + l
  EEA19274.1 318 RFLVHGTRIPFAWiTRLRTYGKKIQNTTTSL 348
                 566666776653314579*******998876 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 5.1e-06
     DUF3974  40 ykrahesieklsnkstpflkeftkhplfyrwirtegkkeqkvlnvlfcaanertreqvfsalpk 103
                 y    e  ++ls k + +  e      f r+++te +k q++l++lf   +e +re v+  +p 
  EEA19274.1 350 YIYWSEDQQQLSYKGLEMTIE-----SFRRFVQTEIEKAQQSLEILFLLYEEESRESVIPPIPL 408
                 555566666666666544333.....599****************************9987775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (620 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       552  (0.0307881); expected 358.6 (0.02)
Passed bias filter:                      458  (0.0255452); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.25s 00:00:00.84 Elapsed: 00:00:00.41
# Mc/sec: 4513.61
//
Query:       EEA19275.1  [L=1412]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-11   44.9   0.0    2.7e-11   43.6   0.0    1.6  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    6.7e-07   29.5   0.1      3e-06   27.4   0.1    2.1  1  rve              Integrase core domain
    6.3e-05   22.8   0.9    6.3e-05   22.8   0.9    1.8  2  gag_pre-integrs  GAG-pre-integrase domain


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.6   0.0   4.5e-15   2.7e-11       7     181 ..     908    1085 ..     901    1129 .. 0.85

  Alignments for each domain:
  == domain 1  score: 43.6 bits;  conditional E-value: 4.5e-15
       RVT_2    7 slPkdrkaigsrWvftkkkddlkevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeee.lvvhqldvdsafLnae..ldeevyvkqP 100 
                  + P + +    r++  +k+   +++  k+rlv+q ++  a++ +  + +P i+  s rL+l la ++e   ++  dv  a+ +++  l+ + yv++P
  EEA19275.1  908 DVPLNIRIFNLRFIDEIKNPRTDKAFEKSRLVVQAYND-ADKTFVLTESPTIQRCSQRLILCLAPCKEdTKLYLRDVTQAYTQSTtlLNRDFYVRPP 1003
                  5688889999999999**988899999*********85.8999*********************87652789999*******998445777****** PP

       RVT_2  101 pGfeidreeekvykLnkslyGlkqapllWnekidkvLkk.lgferseaesGl.yvrgtgegklivalyvddlliagsdikile 181 
                  p  +    +  + k+ + lyG+  a+  W+++ ++  ++ l++e s+    l ++     g  iv++  dd l+ ++d   + 
  EEA19275.1 1004 PELTAT-FQSSILKVIRPLYGIPEAGNHWFRTYHRHHTDrLKMETSTFDPCLlHCSEPNTGFGIVGMQTDDTLLLADDLFAIR 1085
                  *99998.567899*****************9988765542788888888776155555566689*******999999876665 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.4   0.1     5e-10     3e-06       8     112 ..     597     694 ..     591     699 .. 0.83

  Alignments for each domain:
  == domain 1  score: 27.4 bits;  conditional E-value: 5e-10
         rve   8 wqvDvtvvripdgggkayllvvvddfsrlilaealsdemdastvlallera.varfggvepervlsDngseytskafrefladlgirvsftrpgrpqdn 105
                 + vDv++++    g    +l+++d ++r+  a+ l++   a+t+ ++l+ a ++ + g  p+ +++D g+ ++sk+f +f+ + g++    ++   +  
  EEA19275.1 597 IIVDVMYIE----G--RAVLHIIDEATRFNAAHWLPNL-LAKTTWDTLRTAwIDTYLGP-PDFIVTDAGKNFVSKEFSQFATSVGTTAVSVPVEAHWLI 687
                 567888777....3..468999****************.55555566655516666666.*************************************** PP

         rve 106 GkvErfh 112
                 G vEr h
  EEA19275.1 688 GAVERYH 694
                 *****98 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.4   0.4         3   1.8e+04      29      34 ..     499     504 ..     499     504 .. 0.92
   2 !   22.8   0.9   1.1e-08   6.3e-05      21      63 ..     529     574 ..     515     575 .. 0.75

  Alignments for each domain:
  == domain 1  score: -4.4 bits;  conditional E-value: 3
  gag_pre-integrs  29 rRLGHp 34 
                      rR+GHp
       EEA19275.1 499 RRFGHP 504
                      7****8 PP

  == domain 2  score: 22.8 bits;  conditional E-value: 1.1e-08
  gag_pre-integrs  21 kssinlWHrRLGHpsfsrlkkLfkkgllpglkisk....sevCeaCq 63 
                      + ++++ HrR+GHps +rl++L ++ + +g + +      ++C++Cq
       EEA19275.1 529 DVELRRLHRRFGHPSTKRLSQLLER-SGHGTNTEAlehiRRFCHHCQ 574
                      6788999****************84.3444443332234669****9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1412 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       447  (0.0249317); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.84u 0.31s 00:00:01.14 Elapsed: 00:00:00.49
# Mc/sec: 8735.49
//
Query:       EEA19276.1  [L=816]
Description: telomere-associated RecQ helicase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.7e-28   98.7   1.3    7.1e-28   97.3   1.3    1.8  1  OrsD       Orsellinic acid/F9775 biosynthesis cluster protein
  ------ inclusion threshold ------
      0.016   14.9   0.9       0.16   11.8   0.0    2.7  2  zf-H2C2_5  C2H2-type zinc-finger domain
      0.032   13.6   0.9       0.08   12.2   0.2    1.9  2  DUF4729    Domain of unknown function (DUF4729)


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.3   1.3   1.2e-31   7.1e-28       2     113 ..       3     111 ..       2     112 .. 0.97

  Alignments for each domain:
  == domain 1  score: 97.3 bits;  conditional E-value: 1.2e-31
        OrsD   2 lfeyneeyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgLpvyeGyrCrakakCkyltr 100
                 lf+y++eyr++iC++C+yav+ps l  HL k+h++  r ktq  ++++ +em ++++   ++ +e +++p++ s+p+  Lp+++Gy+C  + kC+y++ 
  EEA19276.1   3 LFQYIPEYRIWICQACRYAVSPSRLLAHLAKKHSHDYRTKTQIQRQYILEEMLKKPWI--DPWKESLRFPPPTSAPVACLPIHQGYQC-LSIKCSYIAG 98 
                 8********************************9999999999999**9*********..9***************************.78******** PP

        OrsD 101 slktlrkHlqkkh 113
                 + +t+r+Hl k+h
  EEA19276.1  99 AKDTVRRHLIKQH 111
                 *********9999 PP

>> zf-H2C2_5  C2H2-type zinc-finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.2       0.1   6.1e+02      12      25 ..      23      36 ..      18      37 .. 0.83
   2 ?   11.8   0.0   2.6e-05      0.16       6      24 ..      93     111 ..      92     112 .. 0.96

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.1
   zf-H2C2_5 12 wksnLkRHlrrkHt 25
                ++s L  Hl++kH+
  EEA19276.1 23 SPSRLLAHLAKKHS 36
                6777888******7 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 2.6e-05
   zf-H2C2_5   6 CDYstawksnLkRHlrrkH 24 
                 C+Y +  k++ +RHl ++H
  EEA19276.1  93 CSYIAGAKDTVRRHLIKQH 111
                 ***************9888 PP

>> DUF4729  Domain of unknown function (DUF4729)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.2   1.3e-05      0.08       5      35 ..      15      47 ..      14      56 .. 0.81
   2 ?   -1.4   0.0      0.21   1.2e+03       1      26 [.      86     112 ..      86     118 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 1.3e-05
     DUF4729  5 legCrrlvfssdllaHllsdHlre..pklrlee 35
                ++ Cr  v++s llaHl+++H ++   k+++++
  EEA19276.1 15 CQACRYAVSPSRLLAHLAKKHSHDyrTKTQIQR 47
                789******************988776666665 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.21
     DUF4729   1 ikCPlegCrrlv.fssdllaHllsdHl 26 
                 ++C+  +C+ +  ++++  +Hl+++H 
  EEA19276.1  86 YQCLSIKCSYIAgAKDTVRRHLIKQHP 112
                 58999999987635677889******3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (816 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       592  (0.0330191); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.73u 0.31s 00:00:01.04 Elapsed: 00:00:00.50
# Mc/sec: 4886.09
//
Query:       EEA19277.1  [L=602]
Description: hypothetical protein PMAA_000780 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    0.00059   20.0   0.0     0.0011   19.2   0.0    1.4  1  Myb_DNA-binding  Myb-like DNA-binding domain
     0.0064   16.7   0.0      0.014   15.6   0.0    1.6  1  Myb_DNA-bind_6   Myb-like DNA-binding domain


Domain annotation for each model (and alignments):
>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   0.0   1.2e-07    0.0011       3      45 ..     514     556 ..     512     557 .. 0.89

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 1.2e-07
                      SSBHHHHHHH..HHHHHHHTTCHHHHHHHHTSS-HHHHHHHHHHH CS
  Myb_DNA-binding   3 kWteeEdelL..leavkkhGnrWkkIaerlggRtekqcrsrwrny 45 
                      ++t+eEdel+  l+ ++k+   W+ I+ +++gRt+   + r+ ++
       EEA19277.1 514 EYTAEEDELIvtLKEIEKLP--WSVISAYFPGRTKATLQVRYCTV 556
                      68********8888888888..*************9999999876 PP

>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   1.6e-06     0.014       2      47 ..     516     561 ..     515     574 .. 0.82

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 1.6e-06
  Myb_DNA-bind_6   2 teeEdeiLlklvekygndWknIaealnrRtpkqcfdrwknkLrpki 47 
                     t+eEde+++ l e     W+ I+  ++ Rt+ +++ r++++L+   
      EEA19277.1 516 TAEEDELIVTLKEIEKLPWSVISAYFPGRTKATLQVRYCTVLKKHK 561
                     89999999999998888*********55************885433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (602 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1020  (0.0568911); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.28s 00:00:00.92 Elapsed: 00:00:00.52
# Mc/sec: 3496.94
//
Query:       EEA19278.1  [L=552]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-11   45.0   0.0    3.7e-11   43.4   0.0    1.7  1  APH       Phosphotransferase enzyme family


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.4   0.0   2.1e-15   3.7e-11      11     201 ..     112     375 ..     104     377 .. 0.71

  Alignments for each domain:
  == domain 1  score: 43.4 bits;  conditional E-value: 2.1e-15
                 CEEEEEEETT.--EEEEEE-TT..S-HHHHHHHHHHHHHHH.HTT-B--B-CTTB.S-EEETTEEEEEEE----EE-SS...HHHHHHHHHHHHHHHHH CS
         APH  11 nrtylvttpa.gryvlrrnppa..raaeeirrevallrlLa.kagvpvPevlagd.tddeeigllfalieyvpgrsllr...klsaaqlpellealgef 101
                 nr++ +t  + +r v r++ +    ++ ++++eva  ++L+ k+ vp+P +l++  +  + ig ++ ++e v+g +l+    ++  +++ + ++++ + 
  EEA19278.1 112 NRVFVFTLNKsKRIVARLPFTLagPSKLTTSSEVATIKYLQsKTSVPIPTILDWSnEASNPIGSEYIIMEHVEGVQLHKrwlEMAGDVRVRCIDEIYRK 210
                 77999999887899988877777789***************89999******876688888888***************88888888888888888888 PP

                 HCCHHCH..-STTTB-SHHCHTCCHH................................................................HHHHCHHHC CS
         APH 102 laalhqvd.paalpladflaqdlell................................................................rqlesatar 135
                 l+++ ++  pa+  + +++  +++++                                                                ++++s++ +
  EEA19278.1 211 LKEIVDLKfPAFGSVNFEANLQPNCErislgggfcvgphcgsiywdcnsgepryyhntqpnqgpwttldqycdglvdaglsrippndssmEKRPSYH-G 308
                 8888888777766666444444444444444444444444444444444444444444444444444444444444444444444444446777773.4 PP

                 CCGCCTCCHHHHHHHHHHHHHHHH--S.SS-EEEE-SS-SGGGEEEC...TTEEEEE---TT-EEEEC CS
         APH 136 llaselldlleeleeqvlaalaallpg.elptvllHgDlhpgNllvd.pddgrvtGviDfedaglgpp 201
                 ++++ l+  le++++ + +++++ +   +  ++l H Dlh +N+ v   d+ ++tG+iD++ +++ p+
  EEA19278.1 309 SVQAHLDI-LERCRSVLKEMCKDSRIQaAATPTLFHPDLHKRNIFVSeTDPSKITGIIDWQSTSIEPA 375
                 45545555.67777767777776666689******************999***********9998775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (552 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       321  (0.017904); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.46
# Mc/sec: 3577.18
//
Query:       EEA19279.1  [L=151]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (151 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       733  (0.0408835); expected 358.6 (0.02)
Passed bias filter:                      466  (0.0259914); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.47
# Mc/sec: 966.39
//
Query:       EEA19280.1  [L=118]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (118 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       776  (0.0432818); expected 358.6 (0.02)
Passed bias filter:                      455  (0.0253779); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.25s 00:00:00.67 Elapsed: 00:00:00.41
# Mc/sec: 861.36
//
Query:       EEA19281.1  [L=239]
Description: hypothetical protein PMAA_000810 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (239 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       585  (0.0326287); expected 358.6 (0.02)
Passed bias filter:                      496  (0.0276647); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.23s 00:00:00.65 Elapsed: 00:00:00.37
# Mc/sec: 1946.36
//
Query:       EEA19282.1  [L=80]
Description: hypothetical protein PMAA_000820 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (80 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       635  (0.0354175); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.33u 0.27s 00:00:00.60 Elapsed: 00:00:00.38
# Mc/sec: 626.42
//
Query:       EEA19283.1  [L=133]
Description: hypothetical protein PMAA_000830 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.016   15.4   0.2       0.03   14.5   0.1    1.5  1  Uds1             Up-regulated During Septation
      0.055   13.6   0.1      0.062   13.4   0.1    1.1  1  Cob_adeno_trans  Cobalamin adenosyltransferase
      0.057   13.4   0.2       0.07   13.1   0.2    1.1  1  Laminin_II       Laminin Domain II


Domain annotation for each model (and alignments):
>> Uds1  Up-regulated During Septation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.1     5e-06      0.03      22      67 ..      62     108 ..      54     132 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 5e-06
        Uds1  22 eVeelkkelkaLeerleal.rkkLaletklrdaarsLsrlyssskks 67 
                  V el ke++ L +rl+++ ++kL++++k  ++ +sLs    + k+s
  EEA19283.1  62 NVPELEKECEFLRSRLQQIyTHKLQVNSKWEKGMESLSLHDLRAKAS 108
                 5889************997378**************99888777776 PP

>> Cob_adeno_trans  Cobalamin adenosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.1     1e-05     0.062      31     114 ..       3      89 ..       1     107 [. 0.80

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 1e-05
                      HHHHHHHHHHHHHHHCTTTTHHHHHHHHHHHHHHHHHHHHHHT......-BTCCG-S--HHHHHHHHHHHHHHHHHS--EESEEES-SS CS
  Cob_adeno_trans  31 tvDelnsaiglarallaeeeeelkeaLeeiqneLfdlgaelatp.....ekkkekkkiteeeveelekeideleaelpplksfilpggs 114
                       +De+n +   +   + + +++l++ L ++ +e  +l + +a +        +++kk++e +v eleke++ l+++l+++ ++ l+ +s
       EEA19283.1   3 RIDEVNRTTPTLS--CLALDNNLHTSLFQLRQEAYTLKQWIAEEnedpqGPISQEKKVDEMNVPELEKECEFLRSRLQQIYTHKLQVNS 89 
                      6788888887777..33457899******************987888774556777899889****************99988887654 PP

>> Laminin_II  Laminin Domain II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.2   1.2e-05      0.07      14      86 ..      15      88 ..       2     104 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.2e-05
                XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXX--TTTTTGGGHHHHHHHHHH.. CS
  Laminin_II 14 evleqlaplsqnlentkeklseinrsveetnekvk.dankairdArrsvkkLeklapqLldklkelkqleeass 86
                + l+  ++l++ l ++++++ ++++ ++e ne+ +   ++  +  + +v +Lek+ + L ++l+++ +++ + +
  EEA19283.1 15 SCLALDNNLHTSLFQLRQEAYTLKQWIAEENEDPQgPISQEKKVDEMNVPELEKECEFLRSRLQQIYTHKLQVN 88
                56778899***************************6455555555789******************99987755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (133 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       591  (0.0329634); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.38u 0.24s 00:00:00.62 Elapsed: 00:00:00.38
# Mc/sec: 1056.53
//
Query:       EEA19284.1  [L=176]
Description: hypothetical protein PMAA_000840 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.063   13.7   0.0      0.079   13.4   0.0    1.2  1  Med11     Mediator complex protein
        0.1   13.1   0.3       0.14   12.6   0.3    1.2  1  DUF4600   Domain of unknown function (DUF4600)


Domain annotation for each model (and alignments):
>> Med11  Mediator complex protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   8.8e-06     0.079      34     111 ..      57     129 ..      31     150 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 8.8e-06
       Med11  34 qepaseseeaqkeafkaatstffstLssvdvrLrrqIyaLeeagiitlessaaasagksaakarlepsgvgavgnldv 111
                  ++++ s  +++eafk++ ++ ++t    +++L++ I+aL+e  i   e+s+  +++++  ++rl   +++a+g++ +
  EEA19284.1  57 PKNENVSRREATEAFKKHVTDLMKT---PKTELHNAIRALKEMTIFLGENSKPLKSTRN--NRRLSVAEMEAMGEFLI 129
                 3444555566666666666666655...679***********99997777766655554..77888888888887765 PP

>> DUF4600  Domain of unknown function (DUF4600)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.3   1.6e-05      0.14      21     103 ..      41     123 ..      36     128 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.6e-05
     DUF4600  21 kqiailkeklekirgnpsdrlasirvleklteeelnqllkqLekekkslenqlkdlelrleqEsKayhkandeRkaylaelaq 103
                 + +++ +++++ + + p+++  s r   +  ++++  l+k  + e +++ + lk++ + l ++sK  + + ++R+  +ae+  
  EEA19284.1  41 NNLVTAHQRIHYATNIPKNENVSRREATEAFKKHVTDLMKTPKTELHNAIRALKEMTIFLGENSKPLKSTRNNRRLSVAEMEA 123
                 567788888888888888988888989999999999999999999999999*****************************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (176 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       662  (0.0369234); expected 358.6 (0.02)
Passed bias filter:                      501  (0.0279436); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.29s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 1231.28
//
Query:       EEA19285.1  [L=195]
Description: hypothetical protein PMAA_000850 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (195 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       349  (0.0194657); expected 358.6 (0.02)
Passed bias filter:                      318  (0.0177366); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.37u 0.27s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1470.25
//
Query:       EEA19286.1  [L=66]
Description: hypothetical protein PMAA_000860 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (66 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       331  (0.0184617); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.35u 0.25s 00:00:00.60 Elapsed: 00:00:00.40
# Mc/sec: 494.75
//
Query:       EEA19287.1  [L=270]
Description: hypothetical protein PMAA_000870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (270 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       329  (0.0183502); expected 358.6 (0.02)
Passed bias filter:                      281  (0.0156729); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.23s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1988.15
//
Query:       EEA19288.1  [L=497]
Description: 67 kDa myosin-cross-reactive antigen family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   4.4e-148  494.2   0.0   7.6e-111  371.3   0.0    2.0  2  MCRA      MCRA family
     0.0013   18.4   0.0     0.0033   17.1   0.0    1.6  1  DAO       FAD dependent oxidoreductase


Domain annotation for each model (and alignments):
>> MCRA  MCRA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  125.4   0.0   3.1e-40   2.8e-36       3     153 ..      20     174 ..      18     176 .. 0.91
   2 !  371.3   0.0  8.4e-115  7.6e-111     188     495 ..     166     472 ..     165     473 .. 0.96

  Alignments for each domain:
  == domain 1  score: 125.4 bits;  conditional E-value: 3.1e-40
                 EEEEE--SHHHHHHHHHHHHTT---GGGEEEE-SS-----------------CCC----B-TT-HHHHHHHTTSB-SSSTTSBHHHHHHHHHHH...S- CS
        MCRA   3 kaylvGsGiasLaaAvyLirdakvpgenihileelkvaggsldgagdpekGyvlrggreleehyeclwdLlssipSleepgasvldeieelnke...dk 98 
                 +a+++Gs iasLa+Av+Lirdakvp+ +ihile+ +++g+++ +agd+ +Gy +r+g++++++   +++Ll+ +pS+++++ ++l+ei++ + e   ++
  EEA19288.1  20 NAWILGSSIASLASAVHLIRDAKVPAPQIHILESRDIPGDGIISAGDSVTGYNYRAGCMPTFNDTYMERLLNLVPSTTNSNITLLEEIKKSDVEkpfQD 118
                 79****************************************************************************************997745433 PP

                 ---S--EEETT.TEE-TTTT----C.CHHHHHHHHHCS-GGGCTT-BHHHHS-HHH CS
        MCRA  99 nkskarlvekr.geeavddkklglskkdrlellkLlltkeekLedkrIedvfseef 153
                 +     l++ + g e++d++k+gl  k+r++l+ L++++e++L++krI+d+ ++++
  EEA19288.1 119 SPGTHVLIRGHnGLEKMDVTKFGLGLKNRMHLMLLIFKSEQTLGRKRIDDLNTKKI 174
                 44444555554689************************************977766 PP

  == domain 2  score: 371.3 bits;  conditional E-value: 8.4e-115
                 GGGSTT-TT-B--SS-HHHHCCHHHHHHHHHTT-EEE-SEEEEEEEEEEE.TTEEEEEEEEEEE.TTEEEEEE--TTEEEEEE---SSTT-EE-BTTB- CS
        MCRA 188 isgledlsglkrtkynqyeslilPlvkyLkeqgVdfqfntkVtdiefeeeeedkktvteielekeegeeetieleedDlvfvtnGsitessslGdndtp 286
                 i++l++ + l++t+ynqyes+i P+v++L++qg df+f +kVtdi  ++e +  + v++i++++ +++ee i+++++D+v+v++Gs+t++s+ G+n+ p
  EEA19288.1 166 IDDLNTKKILDCTRYNQYESIIVPIVRFLQNQGADFRFRIKVTDIVRHSE-NGMESVSAITTVQ-DNSEEIIHVSASDIVIVSIGSVTSGSTSGSNTVP 262
                 6789999***************************************9977.66999*******8.66778***************************99 PP

                 -----.--....-HHHHHHHHHHCC-GGG--THHHHSS--TTS-EEEEEEE-SST.THHHHHHHHTS-TSSSS-EEETT-TT-EEEE--SS-SSTT--T CS
        MCRA 287 akleekea....desweLWkklaakspkfGnPekFcsdieeskwesfTvtlkdek.lleriekltknepgtgglvtlkdSnwllsivvnrqphfkeQpe 380
                 +   ++ea    de+w+LW +l +k+pkfG+P++Fc++++es++ +fTvtl+d++ +++r+ +lt+ +pg+g l+tlk+Snw++s+++++qp f++Qp+
  EEA19288.1 263 PLPPSMEAanelDENWSLWLNLGTKNPKFGDPYNFCTHVSESRLGTFTVTLNDTAgFFKRFYELTNGRPGSGNLITLKQSNWMISLCIPHQPFFSDQPK 361
                 966655555678***************************************9976499***************************************** PP

                 T-EEEEEEES-SSSB-SSS-SBGGG--HHHHHHHHHHHHT--HHHHHHHCTTTEEEEEEE-TTTTGGGS---TTSS-BSS-TTBSSEEEESTTSB-S-- CS
        MCRA 381 dvtvlwgYglfpekeGdyvkKpmlectGeEileEllyhLgvpeekieellkssvntipcvmPyitalflpRakgdRPkvvPegskNlAliGqFveiprd 479
                 + +v+wgYgl+p ++G++vk pm+ c+GeE+++Ell hL++p   +e +l++s +tipcvmP++ a +lpR+ +dRP+v Pe+++N+A++GqFvei ++
  EEA19288.1 362 NIEVFWGYGLYPSQKGNFVKMPMTLCSGEELMTELLWHLDFP---MEPILSNS-ITIPCVMPRMAAALLPRTSTDRPDVTPENITNFAMVGQFVEIADE 456
                 *****************************************8...78******.********************************************* PP

                 -SSSHHHHHHHHHHHH CS
        MCRA 480 tvftveysvrtaqeAv 495
                 t+++ +ysvr+aq Av
  EEA19288.1 457 TTVSLDYSVRGAQLAV 472
                 ***************9 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   0.0   3.7e-07    0.0033       4     206 ..      23     254 ..      21     271 .. 0.61

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 3.7e-07
                 EECTSHHHHHHHHHHHHT.T.....EEEEESSSSTTSSGGGSSEEEEESSS..STHHSTH.............HHHHHHHHH.HHHHHHHHHHHSSTTS CS
         DAO   4 iiGGGiiGlstAyeLarr.g.....VtllekgdiagsgaSgrnsgllhsgl..rylpeas.............elarlslea.leelreleeelgidid 80 
                 i G+ i+ l+ A +L r  +     + +le++di+g g  ++   +    +                       l++ +  + + +l+e+ ++ +++ +
  EEA19288.1  23 ILGSSIASLASAVHLIRDaKvpapqIHILESRDIPGDGIISAGDSVTGYNYraG-----CmptfndtymerllNLVPSTTNSnITLLEEIKKS-DVEKP 115
                 7788899********886425578**********99555555554443333330.....1334445555555577877777746888999998.78877 PP

                 EEE.EEEEEEESSHHHHHHHH.HHHHHHHHTTTTE.E.EEEHHHHHHHSTTSTTTS.EEEEETTEEEEEHHHHHHHHHHHHHHTT-EEEESECEEEEEE CS
         DAO  81 yrr.tGllslaadeeeleald.kllallleaglda.e.lldaeevrelepalpgll.galfypdtgqvdpakltaalaraaealGveilegtevtglee 174
                 ++  +G+ +l ++++ le++d  +++l+l++       ++++e+++ ++  +++l  + +++ +    +++  +  + r ++++G++++++ +vt++ +
  EEA19288.1 116 FQDsPGTHVLIRGHNGLEKMDvTKFGLGLKNRMHLmLlIFKSEQTLGRKR-IDDLNtKKILDCT-RYNQYESIIVPIVRFLQNQGADFRFRIKVTDIVR 212
                 65549999999999889987532233333344333211234455555553.2222212233222.33345556666********************966 PP

                 EE.......TCEEEEEEECT.EEEE..EEEEEEE--GGGHH.H CS
         DAO 175 ed.......gkvwgverttp.gend..aadavVnaaGawsd.l 206
                 ++         +++v ++++ ++++  a d v+++ G  ++  
  EEA19288.1 213 HSengmesvSAITTV-QDNSeEIIHvsASDIVIVSIGSVTSgS 254
                 444566455555555.555534443443355***999877643 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (497 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       384  (0.0214178); expected 358.6 (0.02)
Passed bias filter:                      356  (0.0198561); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.40
# Mc/sec: 3699.99
//
Query:       EEA19289.1  [L=642]
Description: hypothetical protein PMAA_000890 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    0.00053   19.9   0.0     0.0011   18.9   0.0    1.4  1  Peptidase_C48  Ulp1 protease family, C-terminal catalytic dom


Domain annotation for each model (and alignments):
>> Peptidase_C48  Ulp1 protease family, C-terminal catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.0   5.9e-08    0.0011      85     134 ..     563     613 ..     526     630 .. 0.76

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 5.9e-08
                    EEEEEEEC.TTEEEEEEEETCCCEEEEE-TTS-SSH..HHHHHHHHHHHHH CS
  Peptidase_C48  85 iiyiPinedgkHWvlliinlpdktililDSlislht.vkkenrpinnlkpy 134
                    i y Pi+ +++H  ll i+  +k i ++DSl+  +t + ++++ i++l + 
     EEA19289.1 563 IFYSPIHHTDSHFTLLEIDDGEKVIRHYDSLAERTTiHGTKKTRIATLVEC 613
                    4478********************************955555555554444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (642 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       598  (0.0333538); expected 358.6 (0.02)
Passed bias filter:                      526  (0.0293379); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.27s 00:00:00.86 Elapsed: 00:00:00.41
# Mc/sec: 4685.44
//
Query:       EEA19290.1  [L=734]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
   6.6e-124  414.0   0.1   4.1e-123  411.4   0.0    1.9  2  DUF3435     Protein of unknown function (DUF3435)
  ------ inclusion threshold ------
      0.028   13.5   0.0      0.068   12.3   0.0    1.6  1  EarP        Elongation-Factor P (EF-P) rhamnosyltransferase E
       0.24   11.5   4.4       0.59   10.2   4.4    1.7  1  DZR         Double zinc ribbon
        1.3    8.9   5.5       0.27   11.0   1.4    2.1  2  zf-C2H2_11  zinc-finger C2H2-type
        1.3   10.0  10.7       0.21   12.5   1.5    2.9  2  zf-C2H2_4   C2H2-type zinc finger


Domain annotation for each model (and alignments):
>> DUF3435  Protein of unknown function (DUF3435)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.0     0.074   2.6e+02     116     213 ..      76     179 ..      74     187 .. 0.78
   2 !  411.4   0.0  1.2e-126  4.1e-123       1     418 []     209     618 ..     209     618 .. 0.99

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.074
     DUF3435 116 eAFkspsltsaedlyrlkvpkgrqqlpLklkpemld.ipvFcra..ereaegvril.kdealtastlns..rlkrlgeiagfeepitpYk..lRrgaak 206
                 +A+k p +++ e l +++   +r +   klk+ + d ++ Fc+   ere++  r + +++al + ++++  +l   g+  +f+ +++ ++  ++++ +k
  EEA19290.1  76 RAYKDPDIDTTERLSDIDPDFNRADGTKKLKERVIDrWHRFCQKnlEREPDCARWSdPEKALRQASADYgrKLPGYGQAGTFNTDWKYFRiyYQDALGK 174
                 79999**************************998876899**853378899999998999999888764225667788888999888887334567777 PP

     DUF3435 207 alneSge 213
                  +++  e
  EEA19290.1 175 KMDK--E 179
                 7777..4 PP

  == domain 2  score: 411.4 bits;  conditional E-value: 1.2e-126
     DUF3435   1 ieDllellrvlltttekrfqlgrqrvqlllllllaaftsnRpgalleLryrDleltlikdPeggrpvllvevtpeftKgklGkkkkntfvlPeiiydps 99 
                 i+D++++++++l+t++krf lg+qr+ l+l l+l++ft+ R++a+l+L+y++l+++l+++P +g+p l + ++pe +K +lG ++ ntf  Peii ++s
  EEA19290.1 209 IDDMIKFNETILQTRKKRFFLGIQRIMLCLALMLGLFTAGRKNAILKLQYKHLRISLLRNPYDGPPILDIAIKPEYIKSFLGITNLNTFSFPEIILGVS 307
                 79************************************************************************************************* PP

     DUF3435 100 LvlsPhvfllgllfrdeAFkspsltsaedlyrlkvpkgrqqlpLklkpemldipvFcraereaegvrilkdealtastlnsrlkrlgeiagfeepitpY 198
                  v+sPh f++gll++++AFk+  ++s  ++++l v+ g+q+lpL+l+++m+d+++Fcr++  +++ +il+d++++ s  n+++++++ei g+ + ++ +
  EEA19290.1 308 FVFSPHMFIMGLLLHARAFKA-DIRSIDNVRSLFVMRGCQELPLPLEEAMDDYYLFCRVDMIDGEPQILRDQPMSDSHYNNAIRSISEIIGLLKWFFFH 405
                 *********************.99*************************************************************************** PP

     DUF3435 199 klRrgaakalneSgevseaqrnlilqHassrtFlkhYlsqkvdkdvqavvlglppqealiraassmsrsiDprrPkeLtdeqkasveedpelqelkrkr 297
                 ++R+g++ +l++ ++vs+++rnl+l Ha+s+tFlk+Y++++ ++d+q++vlgl+p++ + ra +s+sr  D+rrP++L d+qka ve+dpelq ++ +r
  EEA19290.1 406 QFRYGTGGILDDTEWVSDSKRNLVLHHADSSTFLKYYRPRQ-HTDMQEAVLGLKPDKVIGRALTSISRYADKRRPRYLDDTQKALVEDDPELQTAISNR 503
                 *************************************9999.********************************************************* PP

     DUF3435 298 eelkkeleakygqvakakgtelyeelekakrelrnerqrlrrelkkkireeFkeeqpvidierqlsGkaldee.vkedledeqlvpperarlidllltl 395
                 + l +    k++q++++++ +   ++ +a+r+++n+rqrlr++ kk++r+ F++eq+v+di  q +Gk l ee + e+ e e+ +ppe+ +l++ l+ +
  EEA19290.1 504 DALLD----KFQQTPNPTLEQ---DVAEAERNIKNTRQRLRYRRKKEVRHAFSDEQAVKDINAQRAGKILPEEdALEESESEDDTPPEQTMLVERLMAV 595
                 *****....999999999888...9***********************************************9999*********************** PP

     DUF3435 396 ptsetledelerRiaaidavval 418
                 p  +tle e++rR+ a++ ++++
  EEA19290.1 596 PVEWTLEGEWQRRNIATEVIIMY 618
                 **************999987765 PP

>> EarP  Elongation-Factor P (EF-P) rhamnosyltransferase EarP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   1.9e-05     0.068     125     162 ..     391     428 ..     380     479 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.9e-05
                 -----.TTT--SS---SS---------TTHHHHHHHHH CS
        EarP 125 SpqpskglkkyFffpGftektGGLlreaellaereafq 162
                 S  +  gl k+Fff  f+  tGG+l ++e +++ ++  
  EEA19290.1 391 SISEIIGLLKWFFFHQFRYGTGGILDDTEWVSDSKRNL 428
                 5556679*********************9988733332 PP

>> DZR  Double zinc ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   4.4   0.00017      0.59       4      36 ..     665     712 ..     663     724 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00017
         DZR   4 Cgee....lppdarfCseCgtklkavaa...........edrCpsCge 36 
                 C+++    +p++  +C++Cg+k +++++            +rC sC+ 
  EEA19290.1 665 CNNQeprqIPAKPLVCFQCGKKYSQYQSllrhfrpkhmnDRRCKSCTD 712
                 66665566999999**********9999**********99******86 PP

>> zf-C2H2_11  zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.1       1.9   6.7e+03      23      26 ..     313     316 ..     311     317 .. 0.83
   2 ?   11.0   1.4   7.5e-05      0.27       7      25 ..     680     698 ..     678     701 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 1.9
  zf-C2H2_11  23 HlfI 26 
                 H+fI
  EEA19290.1 313 HMFI 316
                 ***9 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 7.5e-05
  zf-C2H2_11   7 CleCGlcftSqlsLsRHlf 25 
                 C +CG +++   sL RH +
  EEA19290.1 680 CFQCGKKYSQYQSLLRHFR 698
                 *****************86 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   1.5   5.8e-05      0.21       2      24 .]     679     701 ..     678     701 .. 0.91
   2 ?    1.4   2.2      0.21   7.6e+02       2      24 .]     706     730 ..     705     730 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 5.8e-05
   zf-C2H2_4   2 kCpiCgksFsskkaLlrHlkthH 24 
                  C +Cgk +s +++LlrH++  H
  EEA19290.1 679 VCFQCGKKYSQYQSLLRHFRPKH 701
                 699***************99777 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.21
   zf-C2H2_4   2 kCpiC..gksFsskkaLlrHlkthH 24 
                 +C+ C  g  +  + +++ H+ ++H
  EEA19290.1 706 RCKSCtdGMEYLEQMHWQCHVTAVH 730
                 7****88888888888999**9999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (734 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       791  (0.0441185); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.68u 0.31s 00:00:00.99 Elapsed: 00:00:00.47
# Mc/sec: 4692.29
//
Query:       EEA19291.1  [L=224]
Description: hypothetical protein PMAA_000910 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-15   57.6   0.1    1.3e-14   54.7   0.0    2.0  2  HsbA      Hydrophobic surface binding protein A


Domain annotation for each model (and alignments):
>> HsbA  Hydrophobic surface binding protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.7   0.0     7e-19   1.3e-14       3     119 ..      33     153 ..      31     154 .. 0.96
   2 ?    0.7   0.0     0.037   6.6e+02       6      24 ..     171     189 ..     170     212 .. 0.76

  Alignments for each domain:
  == domain 1  score: 54.7 bits;  conditional E-value: 7e-19
                 HHHHHHHHHHHHHHHHHHHHHH--SH..HHHHHHHHHHHHHHHHHHHH..HHHTS----HHHHHHHHHHHHH...CHHHHHHHHHHHHHTHHHHHHHT- CS
        HsbA   3 tvisdittistavtaldtavnafnGgasalpilsasnalvsaikkatt..daqasapltdeealalaqavqt...LepdvkaaldaliaKkpafdkagl 96 
                 tv+++i+ i+t ++++++ ++++ Gg ++ +il+  n++++ +k ++   + ++++pltd++  +++ ++++   +e++ k+a+d+li Kk+ + ++g 
  EEA19291.1  33 TVYKVIDYINTTTSDFNARIQSYEGG-DLRNILDGGNKVTRIMKIGAMmvKQKTTEPLTDAQFPSFLLHMGKeggFEDTLKKAMDTLIVKKSLILASGK 130
                 899*********************95.8********************888899999**************5599************************ PP

                 HHHHHHHHHHHHHHHHHHHHHHH CS
        HsbA  97 tslvlssLqdlkaasdaLsdalv 119
                 +s     L ++++as  Ls++++
  EEA19291.1 131 GSKLGLVLYSQQMASIVLSAEII 153
                 *******************9987 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.037
                 HHHHHHHHHHHHHHHHHHH CS
        HsbA   6 sdittistavtaldtavna 24 
                 ++i+ i  av+++dt++  
  EEA19291.1 171 KVIQIIGRAVDTFDTSIHP 189
                 6899999********9975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (224 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       395  (0.0220313); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1481.58
//
Query:       EEA19292.1  [L=432]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.2e-11   41.7   3.6    1.2e-10   41.2   3.6    1.3  1  Phosphoesterase  Phosphoesterase family


Domain annotation for each model (and alignments):
>> Phosphoesterase  Phosphoesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.2   3.6   6.7e-15   1.2e-10     113     328 ..     168     385 ..     154     413 .. 0.76

  Alignments for each domain:
  == domain 1  score: 41.2 bits;  conditional E-value: 6.7e-15
  Phosphoesterase 113 laqeftlcDryFssvlggtepNrlflisgtsdpsGteggpsladpkktvlkgftqktigerLsekgvswaiYqealdnlakskva......... 197
                      la +     +++ ++++++ pN+ ++i+g       +g  +      +   + + +ti++ L+ k vs+a Y+e  +++a+++ +         
       EEA19292.1 168 LATKGKSLTNFH-AITHPSLPNYAAIIAGDF-----FGLAH------EDFYNINATTIYDLLDLKKVSYATYSEWYNPIATFRGPkdcnnyitn 249
                      555555555665.******************.....99965......55778899*******************99555555555555666666 PP

  Phosphoesterase 198 ..........pfnyyvrklkklearrkalkqlglaakq...lekfkkdvkngkLPqvsfikpngandeHp......g.advaagdklikevlea 271
                                + + y+r   ++  ++++ ++++  ak     + f ++v n +LP++++ +p + +++H+        ++++ ++ + +  l+ 
       EEA19292.1 250 gpvdntnpdwGSQIYRRLDVPALLFSTYTTDYERCAKLydaNNTFYDHVMNHSLPKYTYFIPDMLHNGHDpesnsdYvHQPQTAAIWFNSWLDL 343
                      66678888898888999989988899999999887766577889********************8888863332222357999*********** PP

  Phosphoesterase 272 ltsspqwaktllivtyDEngGfyDhVappvapvsdpdglkGdpyglgvrvPllviSp 328
                      +  + + + +l++ t+DE     D  ++p                  +++ +++ ++
       EEA19292.1 344 YLPELEAQGALVVATFDEATWTNDNDYTP---------------NNDNHIVTMLFGA 385
                      ******************98777777777...............2334455555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (432 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       302  (0.0168442); expected 358.6 (0.02)
Passed bias filter:                      246  (0.0137208); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 3057.47
//
Query:       EEA19293.1  [L=302]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      1e-09   38.5   0.0    1.5e-09   38.0   0.0    1.2  1  Bys1             Blastomyces yeast-phase-specific protein
  ------ inclusion threshold ------
      0.038   13.9   0.1       0.13   12.3   0.1    1.8  1  AdoMetDC_leader  S-adenosyl-l-methionine decarboxylase leader


Domain annotation for each model (and alignments):
>> Bys1  Blastomyces yeast-phase-specific protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.0   0.0   1.7e-13   1.5e-09      17     137 ..     169     292 ..     159     301 .. 0.80

  Alignments for each domain:
  == domain 1  score: 38.0 bits;  conditional E-value: 1.7e-13
        Bys1  17 vycnfsvaldveagevstrkildgrsydyynekyrggsgdgvsltlshteg.rdssnsettfrykladdnstveyslgnsggnpfeghkltl...kssd 111
                 vy n +  + +  g+    + +  r  dy+ e+ r+  g gvslt++ + g      s+t f y +      + y + n  g+p++gh +t+   ++s+
  EEA19293.1 169 VYNNCTQNIYLWNGGLVEAENIVLRPLDYHVEDMRPSPG-GVSLTITISRGgLMDGSSRTIFLYDILP--RGIFYGMANFFGDPLQGHPITVlpvNPSG 264
                 788888888888888888888889***********9776.9****9988762456779******9976..5799***************9963337899 PP

        Bys1 112 drcpriewpegiptgvss..gscgssen 137
                  +c  i+w +g+p g  +    cg + n
  EEA19293.1 265 LGCEIIQWSQGLPPGGETrpTLCGLNTN 292
                 *************986541145776555 PP

>> AdoMetDC_leader  S-adenosyl-l-methionine decarboxylase leader peptide
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.1   1.4e-05      0.13      21      34 ..     194     208 ..     191     211 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.4e-05
  AdoMetDC_leader  21 PLgYtvEDvRPh.GG 34 
                      PL+Y vED+RP  GG
       EEA19293.1 194 PLDYHVEDMRPSpGG 208
                      9**********7355 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (302 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       210  (0.0117129); expected 358.6 (0.02)
Passed bias filter:                      199  (0.0110993); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.21s 00:00:00.66 Elapsed: 00:00:00.40
# Mc/sec: 2251.89
//
Query:       EEA19294.1  [L=273]
Description: carbonic anhydrase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      4e-31  108.5   0.2    6.3e-31  107.8   0.2    1.2  1  Carb_anhydrase  Eukaryotic-type carbonic anhydrase


Domain annotation for each model (and alignments):
>> Carb_anhydrase  Eukaryotic-type carbonic anhydrase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  107.8   0.2   3.5e-35   6.3e-31       2     232 ..      38     255 ..      37     266 .. 0.84

  Alignments for each domain:
  == domain 1  score: 107.8 bits;  conditional E-value: 3.5e-35
                     BXXHHHBXGGGHHHHXC....CCC.SSS-S-BEE-GGGCEE-TT-EEEEEESTSSCEEEEEEEE-SSSEEEETTTTCSEEEETTESS.EEEEEEE CS
  Carb_anhydrase   2 wsyeeekgpeeWsekyp....ecg.gkrQSPInietkkakvdpslkplefegydkkekkltlennGhtvqvklkdekptisggplsgkYrleqlh 91 
                     ++y+ + gp +W+  +     +c+ gk+QSP++i+ + +++     +++++ +  +   ++len  + v+v +++   t++    ++ Y+l+q+h
      EEA19294.1  38 FNYTATGGPLNWHLLNTtannACAtGKNQSPVDIVMEGITYAIP-GSVKLD-IPCAG-GVELENLNNVVEVVANNG--TLT--TPESIYKLAQFH 125
                     789888999***8775444458888***************9998.888886.33444.59***********99873..344..33568******* PP

                     EEESSSTTTSSSSEETTB--SEEEEEEEEETTTSSHHHHTTSTTSEEEEEEEEEECS...--GGGHHHHHHGGGG-STTEEEEEEEE-CGGGSSS CS
  Carb_anhydrase  92 fHWGssdekGSEHtidgkrypaElhivhynskysslsealkkpdglavlgvllevge...enpeleklvealkkikkkgksvslksfslsdllpe 183
                     fH        SEH ++++ +p+E h+v+ n+       a+    ++av ++l++++e   +np +++++ +l++i+++g+ ++   ++++++ ++
      EEA19294.1 126 FHT------PSEHRVNEEYFPMEAHFVFENE-------AS----QIAVAAFLFQLSEsgaSNPLFDSVFAHLDDITTPGTFTKTGPLDFTTVNQH 203
                     **8......7******************995.......54....5*********8776778*******************999877999988888 PP

                     .GCS-EEEEEE--SSTT--S-EEEEEESSEEEEEHHHHHHHHHCBC..STTT CS
  Carb_anhydrase 184 .slskYyrYeGSLTtPpcseaVtWtvfkepikisekqlekfrslls..eeee 232
                      s++  ++Y+GSLTtPpcse   W + +ep++++ + ++k++++++   + +
      EEA19294.1 204 fSNHGIFQYSGSLTTPPCSEGLSWYISTEPMPLNVQTYNKVKKVVKfnARYT 255
                     5688**************************************9998542222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (273 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       296  (0.0165096); expected 358.6 (0.02)
Passed bias filter:                      263  (0.014669); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.47
# Mc/sec: 1761.35
//
Query:       EEA19295.1  [L=530]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.3e-26   90.9  25.6    7.3e-26   90.9  25.6    2.0  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.9  25.6   4.1e-30   7.3e-26       6     327 ..      64     440 ..      60     449 .. 0.78
   2 !    5.5   3.4   0.00037       6.6     132     172 ..     464     503 ..     454     516 .. 0.83

  Alignments for each domain:
  == domain 1  score: 90.9 bits;  conditional E-value: 4.1e-30
       MFS_1   6 flsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll.fa.......sslw.lllvlrvlq 95 
                 +++++a s+++++l   l+e+ g+s ++++  ++  +l+ +++ l++ ++s rfG r ++l+++l+ +++l + + ++             +++  +l+
  EEA19295.1  64 WFTGIAVSTVYSVLV-PLSEATGVSTDTLNQGTGYMFLFLGWSLLFWQPFSLRFGKRLTFLISILGGIVTLKITSrYShtrsayvK-TNgEWIAKCILM 160
                 567777777777777.79*************99999**********************************6666687433333422.3336******** PP

       MFS_1  96 GlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllll.............peepperkr 181
                 G++ + + ++  + ++d++   erg ++g+++++ + +  ++p++ g++a++ gWr+vfy  ai++   fv+ +l++             +eep++ ++
  EEA19295.1 161 GFFISPIEALPEICVTDLYFTHERGTYMGIYALTLAGSNYFAPVICGFIAEYQGWRWVFYWPAIFLGATFVFLALFMeetnynrntvamsREEPTTGEK 259
                 ***********************************************************************8888886666666655555444444444 PP

       MFS_1 182 kspkeee.....kgtgpaplvp............awkallkdpvlwillialllfffgfsglltllpl........ylqevlglsglllaglllallal 255
                 ++p+++         +p+++v              +k+ l +    + + ++++++f + ++l+++ +        +    +++s   ++gl +  +++
  EEA19295.1 260 STPAPRItegqqIDNAPKSFVAkmsivtanpdqnMFKHALQSLRY-LGWPVIFYAGFSYGSYLIWFNVlnatasiiLSAAPYNFS-PSIVGLSYLSCCI 356
                 444444488777333333333334444444444444444444433.366666666666666666666633333322246777777.7999999999999 PP

       MFS_1 256 vgailallagrlsdr............lgrrrrlllallllllaalglallavtssavllllvlvliGf.glgfvfpsllalasd 327
                 +++i++l++grlsd             + ++ rl+ + ++++++ ++l+l++v   ++ ++++ +++G+  l+fv+++  +l ++
  EEA19295.1 357 GVIIASLISGRLSDWltiklarrnngiMEAEHRLWPFSICVIVVPASLILWGVG-AQHGVHWFGLIFGMgSLAFVSTMGVTLSVN 440
                 99999**********999999999999888************************.899999999999**7788877776666555 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.00037
       MFS_1 132 lGailgpllggllasslgWravfyilaivsllafvlfllll 172
                 +++++ +++ ++l+ +lg++ +f+ +a++++la ++fl+ +
  EEA19295.1 464 MSFAISYGITPWLT-NLGYQNCFISAAFIGMLASLVFLVMI 503
                 6789999999***9.******************99755544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (530 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       708  (0.0394891); expected 358.6 (0.02)
Passed bias filter:                      343  (0.019131); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.48
# Mc/sec: 3320.18
//
Query:       EEA19296.1  [L=310]
Description: spermidine/putrescine import ATP-binding protein potA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    5.9e-19   68.9   0.1    1.5e-18   67.7   0.0    1.7  2  ABC_tran     ABC transporter
  ------ inclusion threshold ------
      0.011   15.9   0.0      0.096   12.9   0.0    2.3  2  SbcCD_C      Putative exonuclease SbcCD, C subunit
      0.033   14.1   0.3      0.072   13.0   0.3    1.5  1  RsgA_GTPase  RsgA GTPase
      0.048   14.0   0.0        0.1   13.0   0.0    1.5  1  DUF3046      Protein of unknown function (DUF3046)


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.7   0.0   3.3e-22   1.5e-18       3     137 .]       6     136 ..       4     136 .. 0.84
   2 ?   -3.3   0.1       2.6   1.2e+04     115     127 ..     278     290 ..     276     293 .. 0.78

  Alignments for each domain:
  == domain 1  score: 67.7 bits;  conditional E-value: 3.3e-22
                 EEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH...HHHTCHHHHHHHSTTGGTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxx RF
    ABC_tran   3 nvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren...esdeeiekalsklglkelk 98 
                 nvs ++ +g++ a++G +Ga KSt++++l+g++++t G + +++ + +   l++ +k ig++pq++ + pel+v+en   +++ ++ +  +  ++k  +
  EEA19296.1   6 NVSGSIDRGTLAAVMGGSGAVKSTFVNVLMGKTNNTDGIVAVNNSPGN---LRRHKKVIGYVPQDDIVLPELNVYENivhAARCRLPRGWRDADIK--A 99 
                 89**************************************88877655...599***********************6443333333333333333..3 PP

                 CBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  99 dtvvksspssLSgGqkqrvalarallkkpkllllDEpta 137
                 +t+v  ++  +SgGq++rv++ + l+ +p  ++lDEpt+
  EEA19296.1 100 HTNV--GKPIISGGQRKRVSIGMELAAAPMAIFLDEPTS 136
                 5666..6688***************************96 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 2.6
                 HHHHHHHHHHHTS CS
                 xxxxxxxxxxxxx RF
    ABC_tran 115 qrvalarallkkp 127
                 + ++l+ra+l++ 
  EEA19296.1 278 VWLCLCRAMLQQY 290
                 5689*****9986 PP

>> SbcCD_C  Putative exonuclease SbcCD, C subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   2.1e-05     0.096      63      89 ..     125     151 ..     109     152 .. 0.90
   2 ?    0.3   0.0      0.19   8.7e+02      39      56 ..     275     292 ..     234     305 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.1e-05
     SbcCD_C  63 alrlvfLDEAFsklDeesiatllelle 89 
                 a+  +fLDE  s+lD++s+++++++l+
  EEA19296.1 125 APMAIFLDEPTSGLDATSASSMMKTLK 151
                 56789*******************997 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.19
     SbcCD_C  39 qflaylalaaalaalyss 56 
                  + + l+l+ a+ ++y+ 
  EEA19296.1 275 IKQVWLCLCRAMLQQYRA 292
                 566778999999999987 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.3   1.6e-05     0.072     100     128 ..      15      43 ..       6      61 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 1.6e-05
                  SEEEEECSTTSSHHHHHHHHCTT-----S CS
  RsgA_GTPase 100 ktsvlvGqSGvGKStLinallpelelktg 128
                   +++++G SG+ KSt++n+l+++++   g
   EEA19296.1  15 TLAAVMGGSGAVKSTFVNVLMGKTNNTDG 43 
                  67899*****************9655444 PP

>> DUF3046  Protein of unknown function (DUF3046)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   2.3e-05       0.1      19      57 ..     246     286 ..     242     287 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 2.3e-05
     DUF3046  19 arslardhvlselggrTaeeAleaG..vdprdVWralcdaf 57 
                 +++  + h+++ lg+  +++A+e+     +++VW+ lc+a+
  EEA19296.1 246 GATNTDRHTITTLGNTVMRKAMENRgaLRIKQVWLCLCRAM 286
                 6777899******99999****986235789*******997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (310 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       535  (0.0298399); expected 358.6 (0.02)
Passed bias filter:                      476  (0.0265492); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2237.73
//
Query:       EEA19297.1  [L=95]
Description: hypothetical protein PMAA_000970 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.8e-12   47.0   0.0    4.1e-12   46.9   0.0    1.1  1  DIOX_N    non-haem dioxygenase in morphine synthesis N-termin
  ------ inclusion threshold ------
       0.04   13.7   0.0      0.071   12.9   0.0    1.5  1  CvfB_WH   CvfB-like winged helix domain
        0.2   11.7   0.6       0.51   10.4   0.4    1.9  2  DUF768    Protein of unknown function (DUF768)


Domain annotation for each model (and alignments):
>> DIOX_N  non-haem dioxygenase in morphine synthesis N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.9   0.0   6.9e-16   4.1e-12      12      76 ..       6      71 ..       3      93 .. 0.84

  Alignments for each domain:
  == domain 1  score: 46.9 bits;  conditional E-value: 6.9e-16
      DIOX_N 12 dedraavaeqlreAcrevGffyvvnhgvpeelidelfeaareFFalPeeeKekl.akspsfrGysr 76
                +++++++ +ql +A+++ Gff +v hg++ e+i++ f+++++FF+l ee K k    ++s+  ++ 
  EEA19297.1  6 NQRKDEITQQLIAAAENAGFFTLVDHGITIEEIERQFSISKKFFDLLEEIKGKTpDDTKSNNAWEY 71
                467899***********************************************9633345555544 PP

>> CvfB_WH  CvfB-like winged helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   1.2e-05     0.071       9      36 ..      21      49 ..      11      50 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.2e-05
     CvfB_WH  9 engGflpltdkS.dPeeIkavfgmSKkaF 36
                en Gf+ l d+  + eeI+++f++SKk F
  EEA19297.1 21 ENAGFFTLVDHGiTIEEIERQFSISKKFF 49
                567777777764378************88 PP

>> DUF768  Protein of unknown function (DUF768)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.4   8.5e-05      0.51      29      46 ..      10      27 ..       8      49 .. 0.73
   2 ?   -1.8   0.0      0.53   3.2e+03       5      23 ..      48      65 ..      44      67 .. 0.63

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 8.5e-05
      DUF768 29 aeLteklfadAkaagiks 46
                +e+t++l+a+A+ ag+  
  EEA19297.1 10 DEITQQLIAAAENAGFFT 27
                69*************853 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.53
      DUF768  5 gidFlkeWIaenvpetaks 23
                + d l+e I    p+++ks
  EEA19297.1 48 FFDLLEE-IKGKTPDDTKS 65
                5555544.67778888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (95 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       684  (0.0381505); expected 358.6 (0.02)
Passed bias filter:                      544  (0.0303419); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.37u 0.29s 00:00:00.65 Elapsed: 00:00:00.43
# Mc/sec: 667.03
//
Query:       EEA19298.1  [L=334]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.3e-08   32.7   0.0    1.3e-07   31.5   0.0    1.6  1  DDE_3         DDE superfamily endonuclease
    4.2e-06   26.4   0.2    1.6e-05   24.5   0.0    2.2  2  HTH_23        Homeodomain-like domain
    8.6e-05   23.1   5.4     0.0003   21.3   0.0    3.5  4  HTH_32        Homeodomain-like domain
  ------ inclusion threshold ------
       0.01   15.5   0.1      0.021   14.5   0.1    1.5  1  Sigma70_r4_2  Sigma-70, region 4
      0.018   15.2   0.4      0.059   13.5   0.0    2.2  2  HTH_28        Helix-turn-helix domain
      0.045   13.6   0.0      0.095   12.6   0.0    1.4  1  TrmB          Sugar-specific transcriptional regulator TrmB


Domain annotation for each model (and alignments):
>> DDE_3  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.5   0.0   4.2e-11   1.3e-07      75     133 ..     194     250 ..     174     260 .. 0.86

  Alignments for each domain:
  == domain 1  score: 31.5 bits;  conditional E-value: 4.2e-11
       DDE_3  75 alqakkivlilDnasiHkseslrelveeeadrlellylPpySPelNpiEivwsklkrel 133
                 +++  ++++  Dna+ H   + +e+ +   ++++ l +P +SP+lN +E  w +lk++ 
  EEA19298.1 194 KRSRPGTIVMEDNAPAHAHFHQKEIYSF--HDVQRLLWPGNSPDLNAVEPTWFWLKKRT 250
                 33333899*****************999..**************************975 PP

>> HTH_23  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.5   0.0   5.4e-09   1.6e-05       3      48 ..       7      53 ..       5      55 .. 0.93
   2 ?   -2.6   0.2       1.8   5.4e+03      37      42 ..     266     271 ..     262     284 .. 0.54

  Alignments for each domain:
  == domain 1  score: 24.5 bits;  conditional E-value: 5.4e-09
      HTH_23  3 sereRlrillllae.GlsvreIAreLgvsrrTvyrwlkryreeGleg 48
                s++ R++i+ l+   ++ ++++A +L+++r  vy++++r +e+G ++
  EEA19298.1  7 SVETRAQIVALVMIaKMKPQDVAILLNIPRVSVYQIVQRAKEHGYDP 53
                7899*********88************************99999776 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.8
      HTH_23  37 wlkryr 42 
                 w k+++
  EEA19298.1 266 WQKAWE 271
                 555552 PP

>> HTH_32  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0     0.016        48      32      63 ..       9      52 ..       5      66 .. 0.60
   2 !   21.3   0.0     1e-07    0.0003       1      59 [.      38     105 ..      38     114 .. 0.89
   3 ?    1.9   0.1      0.12   3.6e+02      14      29 ..     140     155 ..     121     162 .. 0.75
   4 ?   -3.1   0.1       4.4   1.3e+04      48      56 ..     274     282 ..     256     287 .. 0.58

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.016
      HTH_32 32 evrariiallr...eep..........rWsprqlaarlaeregvk 63
                e+ra+i+al+     +p          r s  q+++r  +++g++
  EEA19298.1  9 ETRAQIVALVMiakMKPqdvaillnipRVSVYQIVQRA-KEHGYD 52
                77888888873222233666666666677777777777.555555 PP

  == domain 2  score: 21.3 bits;  conditional E-value: 1e-07
      HTH_32   1 TvsrwlkRyneeGle.gLkdr.........prrgrprklsdevrariiallreeprWsprqlaarlaer 59 
                 +v+  ++R +e+G++  + +r          r+grp+ ++++ +a iia + ++ r + ++ a++la +
  EEA19298.1  38 SVYQIVQRAKEHGYDpTVNPRiehehvannTRSGRPKVVTEAIEASIIASI-TKDRAGREKSAEYLAYE 105
                 5999*************************9999******************.55599999999999544 PP

  == domain 3  score: 1.9 bits;  conditional E-value: 0.12
      HTH_32  14 legLkdrprrgrprkl 29 
                 ++ L+ rpr+gr++k+
  EEA19298.1 140 FSRLQLRPRGGRKPKF 155
                 567888999**99854 PP

  == domain 4  score: -3.1 bits;  conditional E-value: 4.4
      HTH_32  48 sprqlaarl 56 
                    +++a++
  EEA19298.1 274 PQHRIQAWI 282
                 344455555 PP

>> Sigma70_r4_2  Sigma-70, region 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.1   6.9e-06     0.021      14      53 ..      10      49 ..       9      49 .. 0.93

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 6.9e-06
                  HHHHHHHHHHTS---HHHHHHHHT--HHHHHHHHHHHHHH CS
  Sigma70_r4_2 14 rqreifllryleglsykEIAellgisegtVksrlsRArkk 53
                   + +i+ l  +  ++ +++A ll+i+ ++V++ ++RA+++
    EEA19298.1 10 TRAQIVALVMIAKMKPQDVAILLNIPRVSVYQIVQRAKEH 49
                  6789999999***************************986 PP

>> HTH_28  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0     2e-05     0.059       2      47 ..      11      69 ..      10      74 .. 0.80
   2 ?   -2.5   0.3         2   6.1e+03      28      37 ..     262     271 ..     259     273 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2e-05
      HTH_28  2 Rleiiklla.aGhsvreaArelgisrrtvyrWikryeegGiagLvp............r 47
                R++i+ l++ a +   ++A +l+i r +vy+ ++r  e+G +  v+            r
  EEA19298.1 11 RAQIVALVMiAKMKPQDVAILLNIPRVSVYQIVQRAKEHGYDPTVNpriehehvanntR 69
                99*****777******************************8866654555555555555 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 2
      HTH_28  28 tvyrWikrye 37 
                  v  W k++e
  EEA19298.1 262 AVEAWQKAWE 271
                 6889999998 PP

>> TrmB  Sugar-specific transcriptional regulator TrmB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   3.2e-05     0.095      15      50 ..      15      50 ..      13      52 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 3.2e-05
                HHHHHHCCCHHCHHCCCTTSSCHCHHHHHHHHHHCT CS
        TrmB 15 laLlklgpatadeiaeelgvprskvYevLrsLedkG 50
                +aL++  +++ +++a  l++pr +vY+++++ ++ G
  EEA19298.1 15 VALVMIAKMKPQDVAILLNIPRVSVYQIVQRAKEHG 50
                5899999**********************9977666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (334 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1000  (0.0557756); expected 358.6 (0.02)
Passed bias filter:                      589  (0.0328518); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 2207.31
//
Query:       EEA19299.1  [L=10022]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
          0 1723.4   1.5    1.2e-80  271.2   0.0    7.2  7  AMP-binding    AMP-binding enzyme
          0 1481.7  26.7    1.9e-56  191.7   0.0   14.0 13  Condensation   Condensation domain
      8e-87  285.6   6.8    1.1e-10   41.8   0.0    9.1  8  PP-binding     Phosphopantetheine attachment site
    1.5e-12   48.3   0.0       0.49   11.4   0.0    7.9  7  AMP-binding_C  AMP-binding enzyme C-terminal domain


Domain annotation for each model (and alignments):
>> AMP-binding  AMP-binding enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  256.4   0.2   8.1e-80   3.6e-76       3     423 .]    1039    1435 ..    1037    1435 .. 0.89
   2 !  271.2   0.0   2.8e-84   1.2e-80       2     423 .]    2585    2980 ..    2584    2980 .. 0.89
   3 !  228.7   0.0   2.2e-71   9.9e-68       6     423 .]    3680    4067 ..    3675    4067 .. 0.88
   4 !  185.1   0.1   3.7e-58   1.6e-54       3     422 ..    5211    5606 ..    5209    5607 .. 0.85
   5 !  257.6   0.0   3.6e-80   1.6e-76       3     422 ..    6307    6711 ..    6305    6712 .. 0.88
   6 !  258.6   0.0   1.8e-80   7.9e-77       2     423 .]    7858    8250 ..    7857    8250 .. 0.87
   7 !  257.6   0.0   3.5e-80   1.6e-76       5     422 ..    8956    9347 ..    8952    9348 .. 0.88

  Alignments for each domain:
  == domain 1  score: 256.4 bits;  conditional E-value: 8.1e-80
                   HHHHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEE CS
  AMP-binding    3 eqaaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakvl 98  
                   eq++ +p +va++   +g  +TY+ ld  +n lA+ L  +Gv++++ Va++  +sp  +v++lailkaG++vvp+  + ++e+++ i++d++  v+
   EEA19299.1 1039 EQVKLRPHAVAIHA--DGDDITYARLDVLANGLAKRLVDAGVGPEKFVALCFNKSPWAIVSMLAILKAGGIVVPVGVQHPKERVQSIITDTKTLVM 1132
                   789999******88..9*********************99******************************************************** PP

                   EETCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHHH CS
  AMP-binding   99 iatvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkle 194 
                   +  +ds++ ++        + v +vi +d+d l +    ++++++       ++e++lkp++ a++iYTSG+TG PKGV+l+h++l+++++++   
   EEA19299.1 1133 V--TDSDNGHRF------TDLVPTVIFVDRDHLHDL---PNSKQN------IVQESKLKPENAAFVIYTSGSTGVPKGVVLEHAALCTAMKAH--G 1209
                   *..887763333......345667899998876654...444422......2355689*******************************9996..5 PP

                   HCSCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEEE CS
  AMP-binding  195 trfklkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvll 290 
                   + f+++ + +  ++  + +++++  +++++l++G++v++++++++++   l + ++k kv++ +++ +v++ l  s          + s l++++l
   EEA19299.1 1210 KAFNMTTKTRTAQFSAYTFDVSV-GDIFGTLIHGGCVCVISEEDRMN--NLEASMDKAKVNLAVLTSTVADLLRPS----------EVSTLEVLVL 1292
                   67999999**************8.*****************999944..57899**************99999655..........6788****** PP

                   ESS-EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBE.ETTSEEEEEEEETTS-SEBTT-HHHH CS
  AMP-binding  291 ggeplspellrffralfgeevlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeetgepv.pdgeeGellvrgpgvmkgYlkkpeat 385 
                   +gep  p++++ + +++  ++l++YG++E++++ t+ ++ ++ ++++ +Gk l ++++ +v++++   + p g +Gell+ gp +++gYl++  +t
   EEA19299.1 1293 VGEPAKPSVIETWVEHV--TILNAYGPSECCIHSTCGDPITSVAQASIIGKGL-NTRAWVVNPANIDQLsPIGAVGELLLDGPMLARGYLNDALKT 1385
                   ****************8..49*************9955566666777899995.99*****99875555489************************ PP

                   HHHEEE...........T.CCEEEEEEEEEEETTSEEEEEEECCCEEEET CS
  AMP-binding  386 aeafds...........e.grwlrTGDlgrldedGyleivgRkkdliklr 423 
                   a af++           +  r++rTGDl+r   dG+l ++gR + ++k+r
   EEA19299.1 1386 AAAFIKdlswykehdlkPgHRMYRTGDLVRQSMDGSLTYIGRRDTQVKIR 1435
                   *****8899*****9974456**********99***************96 PP

  == domain 2  score: 271.2 bits;  conditional E-value: 2.8e-84
                   HHHHHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESE CS
  AMP-binding    2 eeqaaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakv 97  
                   eeq+ ++pd+ a+     +  +TY+el++ ++ lA++L+  G+++++ Vai+  +s+  vv++lailkaG+vvvp+  + + ++ + ile+++a++
   EEA19299.1 2585 EEQCLRHPDAQAVCA--WDGEMTYGELNKLSTLLASFLKDNGIGPEKSVAICFNKSCWAVVSILAILKAGGVVVPIAVRHPLQRAKAILEEVNAQI 2678
                   89999********77..7889******************88******************************************************* PP

                   EEETCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHH CS
  AMP-binding   98 liatvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkl 193 
                   ++  +d+ +      + +++++  +v v+d++ + k   l      +      +  ee++pd+ ayii+TSG+TG PKGV+l+h  l++ ++++  
   EEA19299.1 2679 ML--TDQGN------CSQYVDTLPSVHVVDDNLVGKF--L---L--PP----GRVCEEIRPDNAAYIIFTSGSTGAPKGVVLEHSTLSTVLSAH-- 2753
                   **..77765......6666677777889995555444..2...1..21....22344589***************************9998886.. PP

                   HHCSCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEE CS
  AMP-binding  194 etrfklkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvl 289 
                       +++++ +v ++  + +++++  +++++ll+G++v++++ +++l++  l  ++++ +v++++++ +v+  +     +k      d++sl++++
   EEA19299.1 2754 GSKLNIGPKTRVGQFSAYTFDVSI-GDIFITLLHGGCVCVISDEDRLNK--LPYALNNAGVNFMFLTSTVATLIE----PK------DFPSLETMV 2836
                   344667899**************7.*****************9999774..66799**************99993....34......99******* PP

                   EESS-EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTT.SCBEETTSEEEEEEEETTS-SEBTT-HHH CS
  AMP-binding  290 lggeplspellrffralfgeevlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeet.gepvpdgeeGellvrgpgvmkgYlkkpea 384 
                   l+ge+++pe+++ + +++   v+ +YG++E+++++t+ ++ +dk+ +g +G +  ++ + +vD +t  +++p+g+ Gell+ gp++++gYl+kpe+
   EEA19299.1 2837 LVGEAVRPEIIETWGQKV--DVISAYGPSECSIHATFSEPIKDKQDAGNIGVA-FCAGLWVVDSNTiDRLCPTGVIGELLIDGPSLARGYLNKPEL 2929
                   *****************8..49*************997778888999*****9.6889*****999345669************************ PP

                   HHHHEEE............TCCEEEEEEEEEEETTSEEEEEEECCCEEEET CS
  AMP-binding  385 taeafds............egrwlrTGDlgrldedGyleivgRkkdliklr 423 
                   ta++f++            + r++rTGDl+r+++dG+l +vgR + +ik+r
   EEA19299.1 2930 TASSFIKnpswaqkhgmalNRRMYRTGDLVRRNHDGTLTFVGRRDAQIKIR 2980
                   ******88999****9965445***************************96 PP

  == domain 3  score: 228.7 bits;  conditional E-value: 2.2e-71
                   HHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEEEET CS
  AMP-binding    6 aktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakvliat 101 
                   + +p+++a+     +  +TY+e++  ++rlA++L s+Gvk++  + i+ ++s   ++++la+ kaG+++vp+  + + ++++ il+d +a +++  
   EEA19299.1 3680 RDQPNAPAICA--WDGNFTYGEVEGLTDRLAHYLVSMGVKPEMMIPICFDKSSWALISMLAVIKAGGAIVPIGVQHPIQRVRSILQDIGAHMML-- 3771
                   6799*****76..7789*****************************************************************************.. PP

                   CTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHHHHCS CS
  AMP-binding  102 vdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkletrf 197 
                   v ++  ++    ++      ++  +d + +++        + +       + + ++p++ a++i+TSG+TG PKGV+l+h++l++  +++   trf
   EEA19299.1 3772 VGKNYGDRF---QG----LVQTFTVDGALFDQL------PSIR-----G-PLSCVQPHNAAVVIFTSGSTGVPKGVVLEHQALCTGFQAH--GTRF 3846
                   654442222...22....233455664333222......2222.....2.355899******************************8886..6779 PP

                   CCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEEEESS CS
  AMP-binding  198 klkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvllgge 293 
                   +++++ + l+++ + +++++  +++++   G+++++++++++l+  +l ++i+++k+++ +++P+v+  l  s          + + l++++lgge
   EEA19299.1 3847 GIGRHTRTLQFAAYTFDVSI-GDIFMTWQFGGCICVISEEQRLN--HLSGAIAAHKANFAVLTPTVAALLEPS----------KIPLLKTLVLGGE 3929
                   9999***************7.*****************999966..799*****************9999555..........4668********* PP

                   -EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBEETTSEEEEEEEETTS-SEBTT-HHHHHHHE CS
  AMP-binding  294 plspellrffralfgeevlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeetgepvpdgeeGellvrgpgvmkgYlkkpeataeaf 389 
                   ++  ++++++ +    +++++YG++E+++  t  ++  d + +  +G+++ g+ + +   + +++vp g+ Gell+ gp +++gY +k e+t  af
   EEA19299.1 3930 APHLDVVEKWGNSA--RLINAYGPAECSINST-SQELVDLHDIRNIGTAFTGNLWVVDSIDCNGLVPIGVIGELLIEGPLLARGYVQK-EKTDAAF 4021
                   *******9999986..59*************9.88888889999********98888888999***********************98.******* PP

                   EE...........TCC.EEEEEEEEEEETTSEEEEEEECCCEEEET CS
  AMP-binding  390 ds...........egr.wlrTGDlgrldedGyleivgRkkdliklr 423 
                   ++           ++r ++ TGDl++ ++dG+l +vgRk+ ++klr
   EEA19299.1 4022 ITdpewmrrynlrSNRrMYCTGDLVYQNPDGTLVYVGRKDTQVKLR 4067
                   *8899*****9974444***************************96 PP

  == domain 4  score: 185.1 bits;  conditional E-value: 3.7e-58
                   HHHHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEE CS
  AMP-binding    3 eqaaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakvl 98  
                   e+++ +p+  a+ d g +  +TY e ++ +++lA +L slGv+++  Va +  +s+  ++++lailkaG+vvvpl+ + ++  ++ +++++++k++
   EEA19299.1 5211 ERCRVQPESYAI-D-GWDGVFTYDEIENLSQKLAYHLVSLGVGPEVMVATYFGKSVWAIMSMLAILKAGGVVVPLDIQRSSFIVKTMIAQVNSKTI 5304
                   678889999999.3.466789*************************************************************************** PP

                   EETCTCCC.HHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHH CS
  AMP-binding   99 iatvdsel.leklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkl 193 
                   +  v+++   ++ +++       ++++++ +++l +   l+e++ ++      +e+  +kp++ a++i TS T  kP GV+l+hr++++++++   
   EEA19299.1 5305 L--VEDIHhGDHFNDI-------SATVCIVNEDLFDL--LPESKLQA-----ACEH--VKPHNAAFVIHTSDTGDKPIGVILEHRAISTSLQAR-- 5380
                   *..8877733333333.......33444444443333..55544323.....3445..99******************************9993.. PP

                   HHCSCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEE CS
  AMP-binding  194 etrfklkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvl 289 
                    + f l+++ + l++ p a   ++ ++++++l+ G++++++++ +  d + + e++e+++v++ a++P+++  +               +sl++++
   EEA19299.1 5381 GKAFTLDANTRTLQFTPHATGNSI-ADIFATLMFGGCICVSSEQDYID-TNISEVMERYRVSFAALTPTIATSVHGY----------HVPSLKTLV 5464
                   556888899**************7.***************99776666.5678*******************99553..........6789***** PP

                   EESS-EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBEETTSEEEEEEEETTS-SEBTT-HHHH CS
  AMP-binding  290 lggeplspellrffralfgeevlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeetgepvpdgeeGellvrgpgvmkgYlkkpeat 385 
                   + ge ++++ l+ ++ +f+  ++++Y   E +  +t  ++ +  +    +G  ++   + +  ++  ++vp g++Gellv gp +++gYl+++e+t
   EEA19299.1 5465 FTGETVNKSSLEGLSTHFR--LINAYQSIESSFYTTS-TDIDLSRDSMNIGHGVAARMWVVEQDNPHKLVPIGVVGELLVEGPLLARGYLQDEERT 5557
                   *****************94..9*************85.3334444566799998775566656666999*************************** PP

                   HHHEEE...........TCC.EEEEEEEEEEETTSEEEEEEECCCEEEE CS
  AMP-binding  386 aeafds...........egr.wlrTGDlgrldedGyleivgRkkdlikl 422 
                   + af++            gr ++rTGDl+  + dG++ +v+R  ++i +
   EEA19299.1 5558 STAFITdpswvhdygftTGRrLYRTGDLVQQNLDGSIAFVDRRNEQITV 5606
                   *****8899*****9963555**********99*************976 PP

  == domain 5  score: 257.6 bits;  conditional E-value: 3.6e-80
                   HHHHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEE CS
  AMP-binding    3 eqaaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakvl 98  
                   ++a+++p   a+ d   + t TY++ ++ ++rlA +L +lGv++++ V+i  ++s+  ++++lailkaG+ vv l  + + ++++ il+d++a ++
   EEA19299.1 6307 KRAQERPASSAIRD--WNGTRTYSQIESLSTRLAIHLIELGVQPETIVGISFEKSYLTIISMLAILKAGGCVVALGVNHPTQRIQVILRDTGANIV 6400
                   67889999999977..88899*************************************************************************** PP

                   EETCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHHH CS
  AMP-binding   99 iatvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkle 194 
                   +  ++++  ++l+e+a++      v+ +d  e+lk+ +l++   s++        + ++ +++a+iiYTSG+TG PKGV+l+h++l++++ ++   
   EEA19299.1 6401 L--TSQQYRHRLEEIASNS----RVVTVD-TEFLKSLPLQDLHMSNN-------FSDTHFNNPAFIIYTSGSTGVPKGVVLEHGALSTSMLAHG-- 6480
                   *..8888899999999863....455556.46666667776665552.......234678*****************************99973.. PP

                   HCSCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEEE CS
  AMP-binding  195 trfklkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvll 290 
                      +++ d + l+++ + ++ ++ +e++++l++G++v+++++d++++   l ++ie+ ++++ +++P+v+  +  +  ++      d +sl  ++l
   EEA19299.1 6481 AVLGIGIDTRTLQFAAYTFDGSI-MEIFTTLVHGGCVCVISEDDRMS--NLPGAIEAVGANFAVLTPTVAGLF--H--PE------DAPSLTEIVL 6563
                   334455599*************7.*****************999944..588*****************9998..3..34......889*9999** PP

                   ESS-EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEE.......CHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBEETTSEEEEEEEETTS-SEBT CS
  AMP-binding  291 ggeplspellrffralfgeevlegYGlTEttgvvtv.......lpleedkkklgsvGkplpgvevkivDeetgepvpdgeeGellvrgpgvmkgYl 379 
                   +gep+ p+++  + +    +v++gYG+TE+++  t           + + +  + +G +l g  + +   +++++vp g++Gell++gp +++gYl
   EEA19299.1 6564 VGEPIKPSVAVDWARSA--KVFNGYGPTECSILSTLkdfsdcpE-YNPQSALFSNIGSVLSGGLWVVDAVNHNRLVPIGVVGELLISGPFLARGYL 6656
                   **********9998885..59*************8899999853.3445578999*****9955555556778999******************** PP

                   T-HHHHHHHEEE............TCCEEEEEEEEEEETTSEEEEEEECCCEEEE CS
  AMP-binding  380 kkpeataeafds............egrwlrTGDlgrldedGyleivgRkkdlikl 422 
                   +++++t+ +f++            +gr++rTGDl++  +dG++ +vgRk+ +ik+
   EEA19299.1 6657 NDEKKTSASFIDkpvwaveneiefSGRMYRTGDLVYQAPDGSFIYVGRKDTQIKI 6711
                   ***********8899*****9954378***************************8 PP

  == domain 6  score: 258.6 bits;  conditional E-value: 1.8e-80
                   HHHHHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESE CS
  AMP-binding    2 eeqaaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakv 97  
                    e+++ +pd  a+     +  lTY++ld+ ++rl+  L+++G ++++ Vai  ++s+  +v++lailkaG++vvpln + + e++  il+d+++k+
   EEA19299.1 7858 HETCRSQPDSLAISA--WDGNLTYHQLDDLSTRLSFSLMQMGTRPESMVAIHFEKSCWALVSMLAILKAGGAVVPLNVQHPMERILVILDDARVKL 7951
                   578999*******66..7789*************************************************************************** PP

                   EEETCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHH CS
  AMP-binding   98 liatvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkl 193 
                   l+  ++++       + ++++++  v+++d+d l+    l+++     ++    ++++++p++ a++iYTSG+TGkPKGV+l h++l+++++++  
   EEA19299.1 7952 LL--TSHRY------KNHYRDTTLNVLLVDHDYLQS---LPSRP----SK----PSSAVQPHNAAFVIYTSGSTGKPKGVILDHAALCTAMQAH-- 8026
                   **..65544......444556666788888655332...23222....22....35579*******************************9997.. PP

                   HHCSCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEE CS
  AMP-binding  194 etrfklkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvl 289 
                    t+ +++ +++v+++  + +++++  +++++l+ G++++++++ +++d   l++++++ +v++ + +P+v++ l             dl+ l++++
   EEA19299.1 8027 GTTYGMSTQSRVVQFSNYNFDVSI-GDVFIPLFFGGCICVISEQDRTD--NLAGAMQANNVNFAMITPTVARLLNPG----------DLPLLKTII 8109
                   45567888***************7.*****************999966..589******************999444..........999****** PP

                   EESS-EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTT.SCBEETTSEEEEEEEETTS-SEBTT-HHH CS
  AMP-binding  290 lggeplspellrffralfgeevlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeet.gepvpdgeeGellvrgpgvmkgYlkkpea 384 
                   l+ge+ +++ ++++   +  +++++YG++E ++++t+ +l  + +++ ++G +++   + +vD ++  +++p g +Gell+ gp +++gYl++p++
   EEA19299.1 8110 LVGEASQASDIDRWAGYV--RLFNAYGPSESSIFTTYQELVAK-SQAFHIGYAFAS-GMWVVDSSNyHRLMPIGAVGELLIDGPILARGYLNDPQK 8201
                   *****************8..49**************7555555.56668****876.677776654166779************************ PP

                   HHHHEEE.........TCC.EEEEEEEEEEETTSEEEEEEECCCEEEET CS
  AMP-binding  385 taeafds.........egr.wlrTGDlgrldedGyleivgRkkdliklr 423 
                   ta +f++         +gr ++rTGDl   + dG++++vgR++ ++k+r
   EEA19299.1 8202 TAASFINnvkwadhvcPGRrMYRTGDLIQQRLDGSFKYVGRIDSQVKIR 8250
                   ******88899999985555*********888***************96 PP

  == domain 7  score: 257.6 bits;  conditional E-value: 3.5e-80
                   HHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEEEE CS
  AMP-binding    5 aaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakvlia 100 
                     k+pd+ a+     +  l+Y+eld  ++rlA++L +lG k+++ +  + ++s+  +va+lailkaGa+vvp+ ++ ++++++ i+++++a++++ 
   EEA19299.1 8956 SLKQPDACAVSG--WDGDLSYSELDTLADRLAHHLWELGTKPETMIITCFDKSLWAIVAMLAILKAGAAVVPIGTKEPSQRVQSIIANTKASIIL- 9048
                   5689******55..8889*****************************************************************************. PP

                   TCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHHHHC CS
  AMP-binding  101 tvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkletr 196 
                     ++  +++l++ a       + +v+d+ +ll++  l+ ++++         + ++kp++ ay+i TSG+TG PKGV+l+h +l+++++++   + 
   EEA19299.1 9049 -GQKSHIDRLRNMAT------HSVVVDK-GLLES--LPLTQGP--------LNTAVKPHNAAYVIHTSGSTGIPKGVVLEHSSLCSSMKAH--GNA 9124
                   .55555777766554......4677774.43434..3333322........233589******************************9996..567 PP

                   SCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEEEES CS
  AMP-binding  197 fklkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvllgg 292 
                   f+++e+ + +++ ++ +++++  +++++l  G++v+++++d++l+   l++++e+ +v++ +++ +v e l  +  +k      dl+sl+++ l g
   EEA19299.1 9125 FGMGEKTRSVQFSSYTFDISI-GDIFTTLQFGGCVCVISEDERLN--DLAGAMERRRVNFAFLTSTVTELL--H--PK------DLPSLETLALIG 9207
                   9999****************7.*******************9966..489*******************99..4..45......9*********** PP

                   S-EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBEETTSEEEEEEEETTS-SEBTT-HHHHHHH CS
  AMP-binding  293 eplspellrffralfgeevlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeetgepvpdgeeGellvrgpgvmkgYlkkpeataea 388 
                   ep+ p++++++  ++  ++++gYG++E++++ t++   ++++ ++ +G +l g  + +  e+  ++vp g++Gell+ gp + +gYl++ ++t+ a
   EEA19299.1 9208 EPVKPAIIEEWAGHV--QIINGYGPAECSIHSTYNGSLKKRQDASEIGHILTGSVWVVNPENYHQLVPIGVVGELLIEGPLLSRGYLNDVQKTSMA 9301
                   **************8..59*************99444445556889*******66666656668999***************************** PP

                   EEE...........TCC.EEEEEEEEEEETTSEEEEEEECCCEEEE CS
  AMP-binding  389 fds...........egr.wlrTGDlgrldedGyleivgRkkdlikl 422 
                   f++           +gr ++rTGDl+r + dG+l i+gR + ++k+
   EEA19299.1 9302 FVTdpewisrhgfkKGRrMYRTGDLVRQNMDGSLTILGRRDTQVKI 9347
                   **8899******964566**************************97 PP

>> Condensation  Condensation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.3   0.1     0.003        14      32      66 ..     179     213 ..     156     219 .. 0.80
   2 !  130.4   0.0   1.7e-41   7.6e-38       2     456 ..     587    1018 ..     586    1019 .. 0.82
   3 !   89.0   0.2   5.8e-29   2.6e-25      26     453 ..    1686    2105 ..    1662    2109 .. 0.77
   4 !  163.3   0.7   1.8e-51   7.9e-48       1     453 [.    2131    2562 ..    2131    2565 .. 0.85
   5 !  131.9   0.0   5.7e-42   2.6e-38       2     443 ..    3236    3639 ..    3235    3657 .. 0.85
   6 !   65.0   1.8   1.1e-21   5.1e-18       5     188 ..    4291    4472 ..    4288    4488 .. 0.82
   7 !   44.8   0.1   1.5e-15   6.9e-12     278     451 ..    4558    4734 ..    4554    4739 .. 0.84
   8 !  191.7   0.0   4.2e-60   1.9e-56       2     451 ..    4761    5185 ..    4760    5190 .. 0.90
   9 !  152.9   0.0   2.5e-48   1.1e-44       2     433 ..    5861    6256 ..    5860    6266 .. 0.83
  10 !  138.8   0.1   4.5e-44     2e-40       5     450 ..    6936    7376 ..    6932    7379 .. 0.83
  11 !  165.1   0.0   4.8e-52   2.1e-48       1     456 [.    7406    7837 ..    7406    7838 .. 0.86
  12 !  112.8   0.2   3.5e-36   1.6e-32       2     437 ..    8507    8907 ..    8506    8931 .. 0.80
  13 !   93.9   0.0     2e-30   8.9e-27      33     439 ..    9623   10001 ..    9611   10017 .. 0.79

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.003
                   EEEEES---HHHHHHHHHHHHHH-SSCCEEEEE.. CS
  Condensation  32 vlklegeldlerlekalqelierhdaLRtvfleee 66 
                    l +++ + ++ l++ l+ l++rh++LR +  ee+
    EEA19299.1 179 ELAVKPTISETILSTCLNRLVQRHEILRATVHEEH 213
                   567889999*******************9996654 PP

  == domain 2  score: 130.4 bits;  conditional E-value: 1.7e-41
                    EEEEEXXCCHHHHHHHHHHSS....SSSTTEEEEEEE..EES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-...TT-----EEEE- CS
  Condensation    2 qdeyplspaQkrmwfleklee....essaynmqavlk..legeldlerlekalqelierhdaLRtvfleeengepvQvil...eerevelevlei 87  
                    +d++p sp+Q+ + + + +++      + + m+a+l    +g ld+ rl +a+ ++++rh+aLRtvf+e  + +p  + +   +  + ++ +le 
    EEA19299.1  587 EDIVPCSPMQEAIMISQSVDDilyqCAYVFKMTASLNdlQRGPLDPVRLANAWSQVVQRHEALRTVFMES-RSRPGHFDSaifKRVSSPVAFLET 680 
                    788999****9988888776422003333344444432235789999********************875.666655443333777777766666 PP

                    T..TSSSHHHHHHHHHHHHHTC--SCCCS.-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHH CS
  Condensation   88 sdleeseeeeaieefaqkdlqepfdLekg.pLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaew 181 
                    +  +e      i +++   +  p++     ++ r+a+f+ +e++l++ ++  H+i+DG S+ il++d  +lY     ++e+   +  pY++++  
    EEA19299.1  681 E--AE------IRSVIDG-TYTPIKFGMLeIPHRFAIFQKSEKELHIRIDASHTIIDGESIYILFQDAWALY-----NSEVLIEPGCPYRSFVFY 761 
                    6..33......5555553.555888887779*****************************************.....55555556666*****98 PP

                    HHHHHCSHHHHHHHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEE CS
  Condensation  182 eqqyleskdlekeeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgt 276 
                        +++  le++ +YW+++l+g++p + Lp +++++  ++f   ++++++ ++ + +l +l+ e ++tl ++ + a+g +L    g++d+ ++ 
    EEA19299.1  762 ----YNKLSLEESVSYWTNYLSGSEP-TMLPLNYPDSSREQFG--TVALDI-DTSAYQLDRLCGELNITLVNLCQLAWGCVLGNFAGSSDVQFSY 848 
                    ....88899999***********888.78****9999999999..888888.667889************************************* PP

                    EEESSTTCSTCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEEC CS
  Condensation  277 eisgReseikdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeees 371 
                    ++sgR+ +  +i + vG ++nt+  r+ +++a t  e ++++++d  ++++hq  pl +   d++ +++    +  ++ ++ +        + + 
    EEA19299.1  849 VTSGRQAALPGIAKSVGTYINTVSCRLALSPALTIIECLQKIRDDFIQSLSHQFLPLSDR--DSDDDKS--FLKRGNTLLVVQR------NAHTG 933 
                    *******888***********************************************986..6665554..2222345555543......44444 PP

                    CCCSEEECEE...E.....SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTTSBCCC-----HHHHHHH CS
  Condensation  372 qlselklsvssveaeeeskydlsleasetngkltikieYntslFdeetierflerlkelleqviehpeqklselkllsdaekekL 456 
                    + ++   + ++++a + ++ydl +++    +k+++++++  sl de +  ++++ +k+ ++ + ++    +++++l+++ ++ kL
    EEA19299.1  934 SIADDSGRFEVIKAINRTEYDLVMNIEVAPSKIKVNVDFWGSLLDEDFAYKVATAFKMSVLSISSNHGRCIRNISLVNENQALKL 1018
                    4444444456777889*************************************************************99987665 PP

  == domain 3  score: 89.0 bits;  conditional E-value: 5.8e-29
                    TTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-.TT-----..EEEE-T..TSSSHHHHHHHHHHHHHTC--SCCCS- CS
  Condensation   26 aynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvil.eerevel..evleisdleeseeeeaieefaqkdlqepfdLekgp 117 
                     +n+++ l++  e+d++ + +a++ ++++h  LR +f     +++    + ++ e++l   + +  +  +++ e aie +a+  +q++++Le gp
    EEA19299.1 1686 RFNQSFLLRVLTEVDSNDFIQAMDVIVQQHGMLRARFHPS-VTDIS---WtQTLETNLfgSYHNGVHSVTTM-ELAIEVMAS--SQRSLNLELGP 1773
                    59***********************************544.33332...22444444411334444434443.556777777..7********** PP

                    SEEEEEEESSTT.EEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHHHHHHHHHHHHHHH......S- CS
  Condensation  118 Lfraalfkiaen.rlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskdlekeeaYWseqlegelpvlqL 211 
                     f + l+k++++ + ll+l+ HH+++D vS++i+l dl kl     + ++lp  ++  ++    w ++ le ++ ek++ + +  +e      qL
    EEA19299.1 1774 VFSVDLIKLQSSgEQLLFLTAHHLVIDLVSWRIILHDLEKLL----RDKSLPPHTSLTFQ---HWTEDLLEHDKAEKSNIHVTLPFEI----GQL 1857
                    ********98762678889********************998....55555443333266...5555578888778877776655553....345 PP

                    --B..SS---SS---S-EEEEEE.EE-S-HHHHHHHHST.SS-HHHHHHHH.HHHHHHHHHT-SEEEEEEEEESSTT..CSTCHHC--SS-EEEE CS
  Condensation  212 pkd..karpakrsfkadrlsikl.deeteeklrklakeq.gvtlndvllaa.lgllLskytgqddivvgteisgRes..eikdiermvGlFvntl 299 
                      +   ++p+ + + +++++  l de+++++l   ++e+ +++  d+lla  ++ +      +d  ++  e++gRe     +d+ ++vG+F+  +
    EEA19299.1 1858 NWRywGIDPETNFYADETIETVLiDEKITSLLFGKCNESlQTETIDLLLATiFHSFRLAFPDRDVPAIFNEGHGREVwnDSIDVTQTVGWFTTFV 1952
                    444445566666666565554445******9998887764899999999861555555666666679999******988779************* PP

                    EEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HH....CCCEEECCCC.SEEECEE...E.... CS
  Condensation  300 PlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgq....eseeeesqls.elklsvssveaeees 389 
                    Plri     +++ +++k +k+  +++ p  g p+ +  + l++++++s s   +p++ f ny g     e e + ++l+   ++++s+v++++ +
    EEA19299.1 1953 PLRIPT--VENLLDIVKWTKDLRRRI-PGHGLPYFSS-QFLRTDENASVSSDWNPEVIF-NYVGRsqqlEREDSLFRLEhIRDPRLSPVGKRTRR 2042
                    ****99..999*********999999.*******996.89999****************.***99876655555555553567889999977777 PP

                    .SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTTSBCCC-----HHHH CS
  Condensation  390 kydlsleasetngkltikieYntslFdeetierflerlkelleqviehpeqklselkllsdaek 453 
                       ++++a  ++++l++++  n+ + d ++++++   +k +l++++++   k++++ +lsd+ +
    EEA19299.1 2043 LGLFEISAIVESDSLRVDFRLNKHVRDLNSVKTWVAAYKATLLDMTSQL-VKVDRIYTLSDFAM 2105
                    777888899999********************************99885.56777777887766 PP

  == domain 4  score: 163.3 bits;  conditional E-value: 1.8e-51
                    EEEEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES.....---HHHHHHHHHHHHHH-SSCCEEEEE....TTEEEEEE-TT-----EEEE-T CS
  Condensation    1 vqdeyplspaQkrmwflekleeessaynmqavlkleg.....eldlerlekalqelierhdaLRtvfle..eengepvQvileerevelevleis 88  
                    v+d+y  sp+Q+++++ +  +  +  y +q v ++++     ++d++rl +++q +++rh +LRt+f+    ++g+  Qv+l++ e+++ +l+  
    EEA19299.1 2131 VEDVYHCSPMQQGILISQLKS--PATYQIQQVCEIKPrqdhnAIDIDRLVDSWQRIVDRHSILRTIFVSsiSDDGTWDQVVLKKWEADISYLKDV 2223
                    5899**********9877766..667888888888652222268889********************99544899999**********9554433 PP

                    ..TSSSHHHHHHHHHHHHHTC--SCCCS-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHH CS
  Condensation   89 dleeseeeeaieefaqkdlqepfdLekgpLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweq 183 
                       +   e+ ++ fa+k   +  +L ++p+ r+ +f+  ++r + +++v H +vD+ Sl++ll + +++Y    +g+ l ++  + Y  y+    
    EEA19299.1 2224 --LD---EDVLDCFAEK--PHLEQLPNQPCHRITVFQTLTKRIYAYFEVSHALVDASSLNLLLDEWIAAY----DGSLLFTSAPK-YNAYIGF-- 2304
                    ..33...4469999996..6666899********************************************....88887775555.*****99.. PP

                    HHHCSHHHHHHHHHHHHHHH......S---BSS---SS---S.-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEE CS
  Condensation  184 qyleskdlekeeaYWseqlegelpvlqLpkdkarpakrsfka.drlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgte 277 
                      l++   e++ +YW+e l+  ++  ++   k ++ +  +++ d ++++ + + + +l+++ +++++t+ +v + a++++Lskytg+++  +g  
    EEA19299.1 2305 --LQQHSAEESLTYWTEHLKD-AEICKIVGSKGSTSDLGTRGtDFQTVAKAFSATPQLNQFVEKNDMTIATVVQLAWAIVLSKYTGSQKPTFGYL 2396
                    ..77788889**********8.66677666655555544443145556668899***************************************** PP

                    EESSTTCSTCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEECC CS
  Condensation  278 isgReseikdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeeesq 372 
                     sgR  ei+dier+ G  +n++   i+++ + + ++ +++++++ l+ + hq++pl ++++ l+l  +     Lf++++s++   ++++ e+ s 
    EEA19299.1 2397 SSGRDAEIEDIERIAGPLINMMVAHIKLDSSMSITKTMEQIQDNFLNGFTHQRTPLVDIQHGLRLGDT----RLFNTSLSYKPWATNDVNESHSL 2487
                    ****************************************************************8886....7********88333333333322 PP

                    CCSEEECEE...E.....SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTTSBCCC-----HHHH CS
  Condensation  373 lselklsvssveaeeeskydlsleasetngkltikieYntslFdeetierflerlkelleqviehpeqklselkllsdaek 453 
                         ++ ++    + ++yd++l ++   ++++ +++Y+++   + + + +le ++++l+ +i++ +  l +++++s  e 
    EEA19299.1 2488 ----IIN-HVT-GIDPTEYDINLDIVGGPQAFSATLQYSSTSMTNDDATSLLESFLQVLHSMIDESTIMLGDIDMVSAYEI 2562
                    ....222.222.366788*********************************************************998775 PP

  == domain 5  score: 131.9 bits;  conditional E-value: 5.7e-42
                    EEEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----.EEEE-T..TSSSH CS
  Condensation    2 qdeyplspaQkrmwflekleeessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvileerevel.evleisdleesee 95  
                    +d+yp +p+Q+++++l+  +  ++ y+ q v++l++++d + +++a+ +l+   ++LRt+++e       Qv+l + ++e+ ++ +++       
    EEA19299.1 3236 EDVYPCTPLQEGLLVLSAQD--PKQYISQRVFRLTEAMDFQKFQDAWSHLFGLVPILRTRIIEG-----QQVVLRH-SIEWqYASDLR------- 3315
                    799************99766..889************************************865.....4555544.34441233344....... PP

                    HHHHHHHHHHHHTC--SCCCS-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHH CS
  Condensation   96 eeaieefaqkdlqepfdLekgpLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskd 190 
                     + +++ +++ +  ++ L++   ++ +      ++ +++++ HH + DG+S++++++ l ++Y    +g+++p+  + pY ++ +      ++ d
    EEA19299.1 3316 -RYLSNDKERSMLPGMALSRYAMVKEQSSV--GKSQYFVWTAHHSVYDGWSVNLIFEALYAIY----QGNDIPD--IVPYTRFLKY----IQEID 3397
                    .33444445555569999999998887766..688899*************************....9999888..6668888887....55577 PP

                    HHHHHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEESSTTCS CS
  Condensation  191 lekeeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisgResei 285 
                     e+ ++YW+ q+++   ++q+p+     ++ ++   + s  +  + e +++  +k   +++   l aa++l+ s+ +g+ d+  g++ sgR  ++
    EEA19299.1 3398 TESMKSYWRSQFSH-WTSNQFPPL----PDHDYI-PQPSNIC--QREIEVTASTKPATASIAIMLRAAWALVVSQHQGNADVLLGVPLSGRSVPV 3484
                    889**********9.666888887....555555.3444444..3344678889999999*********************************** PP

                    TCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEECCCCSEEECE CS
  Condensation  286 kdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeeesqlselklsv 380 
                    ++i +++   + t+P+ri+++ +++  +++ +v++++++++p + ++l+++++ ++++   +  p f++ ++ +     +se  e+  s++    
    EEA19299.1 3485 QGILDIIAPTITTVPVRIKLDYSESVGDYLAKVRQQAVEMMPFEHTGLQQIQRVVKTET--GVAPEFQHLLVVQP----KSEIGENPASRFSCLE 3573
                    ******************************************************99777..58999*******99....7777777777777777 PP

                    E....E.....SSEEEEEEE..TTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTTSBCC CS
  Condensation  381 ssve.aeeeskydlslease..tngkltikieYntslFdeetierflerlkelleqviehpeqkls 443 
                    ++v+ +   + y+l++e  +  ++g  +++  +  s   + +++++le+++ + eq+i+h e  ++
    EEA19299.1 3574 EVVTdNIGFEGYALTVECITdmDKGVVQVEARFDDSIIPRIKVDKLLEQFELVFEQLIRHSERNEN 3639
                    999999***********99989999**********************************9987654 PP

  == domain 6  score: 65.0 bits;  conditional E-value: 1.1e-21
                    EEXXCCHHHHHHHHHHS......SSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T..TSS CS
  Condensation    5 yplspaQkrmwflekle......eessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvileerevelevleisdlees 93  
                     plsp+Q  +++++ +       ++ + yn++++++l   ++++ +++a+++++ +h+ LR +f ++      Q+i+ +++ + ++    ++++s
    EEA19299.1 4291 FPLSPMQ--QFYFQSMAaadmdvTGDNRYNQSLSVTLLRHVESTKIQQAIDSIVIKHPMLRARFHKDVSRGWAQTIHASAHESYRFRFHDNVTMS 4383
                    699****..6666666512222245799************************************9998999999999666555544333334555 PP

                    SHHHHHHHHHHHHHTC--SCCCS-SEEEEEEESSTT...EEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHH CS
  Condensation   94 eeeeaieefaqkdlqepfdLekgpLfraalfkiaen...rlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqy 185 
                    e  + ++++       +++Le+gpLf + lf i e    r ll+l  HH+++D vS++i+++dl ++     +g+ ++l++  +++++ ++++++
    EEA19299.1 4384 E-VSNTKTVSH----GSLNLENGPLFSVDLFHIPEAngiRQLLFLCAHHLVIDFVSWRIVMKDLEEFA----QGRMISLKSPASFRQWSQHQSKQ 4469
                    4.444555555....6*****************88733357899*********************999....*******99999*******9988 PP

                    HCS CS
  Condensation  186 les 188 
                    l+ 
    EEA19299.1 4470 LQT 4472
                    775 PP

  == domain 7  score: 44.8 bits;  conditional E-value: 1.5e-15
                    EESSTT..CSTCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEE.EEESSS-HH....C CS
  Condensation  278 isgRes..eikdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpv.fsfenylgq....e 365 
                     +gR+   +++d++++vG+F+  +Plr++   +++  +++kr+k++ +++   q++  + L k+++ ++++  +  +d++ ++f ny g     e
    EEA19299.1 4558 SHGRNTleADIDLSDTVGWFTTLVPLRVTG-SSNSAMDILKRTKDARRSS--MQRTHRYMLAKYSASKHTA--HGTLDVMeIVF-NYAGRsqqlE 4646
                    799*999999******************99.5556889****99988887..899999********99974..55566543888.9999974443 PP

                    CCEEECCCC.SEEEC.EE...E.....SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTTSBCCC-----HH CS
  Condensation  366 seeeesqls.elkls.vssveaeeeskydlsleasetngkltikieYntslFdeetierflerlkelleqviehpeqklselkllsda 451 
                         ++l+ + ++  +s+++++  +++ ++++ s  n++lt+ ++++ +  ++  i+++++ +++ ++q++e+ ++  +++ ++sd+
    EEA19299.1 4647 TAGRLFNLDsQSPMDeISPIGDNVRRPFIFEIISSVFNSELTFMFHFHHEIHHQDAIREWISGYRTSIQQLVEELAKADRDIYTISDF 4734
                    3344455552444555556669999**********************************************************99997 PP

  == domain 8  score: 191.7 bits;  conditional E-value: 4.2e-60
                    EEEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES...---HHHHHHHHHHHHHH-SSCCEEEEE....TTEEEEEE-TT-----EEEE-T..T CS
  Condensation    2 qdeyplspaQkrmwflekleeessaynmqavlkleg...eldlerlekalqelierhdaLRtvflee..engepvQvileerevelevleisdle 91  
                    +d+yp sp+Q+++++ +  +++++   ++  ++       +d + l ka+q +i+rh++LRt+f+e     g + Q +l++    +e+  +s  +
    EEA19299.1 4761 EDVYPCSPIQQGILISQAKSPGTYQIRHSCEVRSPDpslPIDMQQLVKAWQVVINRHPILRTIFIESqvRAGCFDQLVLKSWIPRIETGLLS--D 4853
                    799*******************9999999999986533369999********************9963456788899999999999999999..6 PP

                    SSSHHHHHHHHHHHHHTC--SCCCS.-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHH CS
  Condensation   92 eseeeeaieefaqkdlqepfdLekg.pLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqy 185 
                    e++ +++i+e+ +       + e+g p+ r ++f+ +++rl++l+++ H +vD+ S+ ++l dl+k+Y    +g +lp+ + ++Y++y+      
    EEA19299.1 4854 EETPQSHIDEVPR------WEYETGkPCHRLMVFSTTDTRLHILFEISHALVDASSVDLILSDLFKAY----QG-KLPSHPGPSYSTYIAY---- 4933
                    6666899****99......6888888******************************************....55.567889999*****99.... PP

                    HCSHHHHHHHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEES CS
  Condensation  186 leskdlekeeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisg 280 
                    l++ + e++ +YW ++le+ +p  ++p+  a +  ++ ++   s++ d +  ++l ++a+ +g+t  +vl+ a++++Ls ytg++++v+g  +sg
    EEA19299.1 4934 LQNSESEEDLKYWHQRLENIEP-CEFPSL-AANMTQQSEDGISSVNTDLDEFQALADFASTHGITAANVLQLAWAVVLSMYTGSEKVVFGYLASG 5026
                    55566779**********9555.9*****.8888888888******************************************************* PP

                    STTCSTCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEECCCCS CS
  Condensation  281 ReseikdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeeesqlse 375 
                    R  +ik++++mvG  +n++   +d++++ t    + ++++++ + + hq++ l ++ + l+l+      +Lf++ +s+       ++ + s+ s+
    EEA19299.1 5027 RDAPIKNVSEMVGPMINIMVTTLDIDRQATILGTLCEIQNAAIEGLHHQRTSLIDIHHALKLKDR----KLFNTTVSY-------KYDNGSRDSS 5110
                    *************************************************************9986....7********.......4588888888 PP

                    EEECEE....E.....SSEEEEEEE.TTSSEEEEEEEETTTS-HHHHHH.HHHHHHHHHHHHHHSTTSBCCC-----HH CS
  Condensation  376 lklsvssve.aeeeskydlslease.tngkltikieYntslFdeetier.flerlkelleqviehpeqklselkllsda 451 
                    + +    +e ae+ ++yd++l++s+  +g+ ++ + Y t  F   +i r +l+ +ke+++ ++++p+++l +l +++++
    EEA19299.1 5111 FIIA---SEiAEDPTEYDVNLNVSKrPDGRTQLYLRYGTR-FMTDDIARhILQIFKETVSSLLKNPNARLVDLLTITED 5185
                    8888...55567************989************9.6666665527899***************9999888776 PP

  == domain 9  score: 152.9 bits;  conditional E-value: 2.5e-48
                    EEEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T..TSSSHH CS
  Condensation    2 qdeyplspaQkrmwflekleeessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvileerevelevleisdleeseee 96  
                    +d+yp +p+Q+++ +++    +ss+y  q+v+ ++ +ld+ r+++a+q++ +  ++LRt+++++   +  Qv+   +++++     +  ++    
    EEA19299.1 5861 EDMYPCTPLQEGLMTISAT--QSSSYTKQHVFIMDRSLDVGRFKSAWQQIANSMPILRTRIIMDSFSRSSQVVVR-SDIQW-----N--DA---- 5941
                    89**********9998865..5******************************************99999999974.56666.....3..22.... PP

                    HHHHHHHHHHHTC--SCCCS-SEEEEEEESST.TEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHH CS
  Condensation   97 eaieefaqkdlqepfdLekgpLfraalfkiae.nrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskd 190 
                    +++++++++d+++ +d  +  L+r++l+k ++ +r +++++ HH i DG+ ++ +l++ a++Y    +g ++  ++++ Y ++++     l++ +
    EEA19299.1 5942 MDLQKYLSEDIANRMDYGS-ELLRFGLVKSTSnERIYFIWTAHHSIYDGWTTSKILQSVAQIY---FHGYTP--QPVP-YNEFIQF----LQESN 6025
                    2366777777777788654.78999999976516799**************************...666663..3466.9999998....67777 PP

                    HHHHHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEESSTTCS CS
  Condensation  191 lekeeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisgResei 285 
                     e+e++YW+ ql++  +++ +p+   +  + + + ++++ +        l+  ++e+++t  ++  aa++ll+s+ t++dd+++g + sgR  ++
    EEA19299.1 6026 KEEEKDYWRSQLAK-NNSVGFPETPGPEHEPNPS-EKIACD--------LQLDTNESNITTSTLIRAAWALLISQETQSDDVIFGAPLSGRAAPV 6110
                    899**********8.5556699994444444444.444444........577789**************************************** PP

                    TCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS..SS-SSSS-S-SEEEEESSS-HHCCCEEECCCCSEEEC CS
  Condensation  286 kdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdle.lqrkesrspLfdpvfsfenylgqeseeeesqlselkls 379 
                    ++i +++G  + t+P+ri++++a+   e+++rv++++ ++ p + ++l+ +++     q + + + L+++ ++++ +  +++++e + l++ +++
    EEA19299.1 6111 SGILDILGPTLTTVPVRINIDRAQPVLEFLSRVQQQATDMIPFEHTGLQYIQRLISdGQPTLDMQRLLQHLLVIQPTARDDNSSEFPGLEAVPVE 6205
                    ******************************************999999999886540455557799**********7777777777777777777 PP

                    EE...E.....SSEEEEEEE..TTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHH CS
  Condensation  380 vssveaeeeskydlslease..tngkltikieYntslFdeetierflerlkelleq 433 
                         +e   +y l ++     ++++ +++ ++ +++    +++r+l r++ +  q
    EEA19299.1 6206 -----DEGFFNYPLIVICNVdnDTNSVHVEAQFDKAVVPHTQMSRLLHRFQSIFCQ 6256
                    .....677889999998888567777788888888888888888888888776655 PP

  == domain 10  score: 138.8 bits;  conditional E-value: 4.5e-44
                    EEXXCCHHHHHHHH.....HHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----E.EEE-T..TSS CS
  Condensation    5 yplspaQkrmwfle.....kleeessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvileerevele.vleisdlees 93  
                     pl+p+Q r++f +      +  + + yn++++lkl++++d+  + +a+++l++ h+ LR +f   + +e  Q+i+e+ + + +  l++   +++
    EEA19299.1 6936 FPLTPIQ-RLYFESiagdkLNVAHDNRYNQSFCLKLRQYIDPLEIDRAVKSLVTSHPMLRARFSPPQSDEWSQTIEESIDGSYKcQLHLV--TKD 7027
                    69*****.888876222223557899*************************************9999*********77665552023444..333 PP

                    SHHHHHHHHHHHHHTC--SCCCS-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCS CS
  Condensation   94 eeeeaieefaqkdlqepfdLekgpLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyles 188 
                    +  + ++ +a   +q+++dLe+gp f   l+   ++  +l+l+ HH+++D vS++++ rdl +l     +g+++++ +  +++++   +q+y  +
    EEA19299.1 7028 K--DMMNLIAH--SQSTLDLENGPVFSTDLVAFPDKTQFLFLTAHHLVIDLVSWRLISRDLEQLI----QGKQISSNPGISFASWSRFQQRYVPN 7114
                    3..34566666..79**********************************************9999....***********9*****999988766 PP

                    HHHHHHHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHHHHST.SS-HHHHHHHH.HHHHHHHHHT-SEEEEEEEEESS CS
  Condensation  189 kdlekeeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrklakeq.gvtlndvllaa.lgllLskytgqddivvgteisgR 281 
                      ++      ++ ++    +  + +  +++ ++s++    +i ++e+++++l  +++e+  ++  d+llaa ++ +L+   g++   +  e++gR
    EEA19299.1 7115 S-VQAGLPVETQSMK--WSYWGVDEI-NNLHENSVE---EAIVINESLTSQLFGTCNETmRTEPLDLLLAAlVHSFLQCFPGRKAPTIFDEGHGR 7202
                    5.3333322222222..233333344.666666776...6777899**********9983577788888762689******************** PP

                    TT..CSTCHHC--SS-EEEEEEEEE--TT-.BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HH....CCCEE CS
  Condensation  282 es..eikdiermvGlFvntlPlridvkeak.tfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgq....eseee 369 
                          +d++++vG+F+++lP+ + +++++ +  ++++r+k+  +++ p++g+p+  L + l+ +  ++ +   + +++f ny g     e    
    EEA19299.1 7203 DVgdDAVDLSETVGWFTSMLPVYVPMEDNQdDILDILRRLKDIRRSI-PNKGIPYF-LSRFLAPEGRKEFESHRQMEVTF-NYTGRyqqlERNDG 7294
                    9988779*******************98764888*******999999.******95.77889888888999999******.**999888877778 PP

                    ECCCCSEEEC.EE...E.....SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTTSBCCC-----H CS
  Condensation  370 esqlselkls.vssveaeeeskydlsleasetngkltikieYntslFdeetierflerlkelleqviehpeqklselkllsd 450 
                     ++l +l+ +  s+++ ++++   ++++as  ng+l++ +++n+ + ++ +i+++++++   le+++++ +++ +++ +l+d
    EEA19299.1 7295 LFELHSLDSEeTSPIGPKTKRMAIFEIIASVFNGQLKLGFSFNRYAKHQRQIQNWISTYSVSLERLVSELSHQTDNIYTLTD 7376
                    888888888844455556666666899999999*****************************************99988876 PP

  == domain 11  score: 165.1 bits;  conditional E-value: 4.8e-52
                    EEEEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEE......EES---HHHHHHHHHHHHHH-SSCCEEEEE....TTEEEEEE-TT-----EEEE- CS
  Condensation    1 vqdeyplspaQkrmwflekleeessaynmqavlk......legeldlerlekalqelierhdaLRtvfle..eengepvQvileerevelevlei 87  
                    v+d+yp sp+Q+++++ +  ++  + y +  v k       +g ++l+rl++a++ ++ rh++LRt+f+      + + Q +l++ + ++e++  
    EEA19299.1 7406 VEDIYPCSPIQQGILMSQVKSP--TTYQIRQVCKlhdgsgSTGTINLSRLQSAWKDVVGRHPILRTIFIDclSTSNIFDQLVLKTFQPSVEIISC 7498
                    5899***********9887765..55555555551133334789************************975345566679999888888888888 PP

                    T..TSSSHHHHHHHHHHHHHTC--SCCCS.-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHH CS
  Condensation   88 sdleeseeeeaieefaqkdlqepfdLekg.pLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaew 181 
                    +   +++    + e+       +++ e g p+ r + f  ++ +++ l+++ H +vD+ Sl++++ dl ++Y      ++l +++ + Y+ y+  
    EEA19299.1 7499 E--IGDDFSIRMGELP------NLNYEGGrPCHRLSFFYKETGHVYALFDISHALVDASSLSLIVYDLKQAY-----DQKLTTSSGPRYSAYIAF 7580
                    8..5555323344444......59999999*********9********************************.....77777878888*****99 PP

                    HHHHHCSHHHHHHHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEE CS
  Condensation  182 eqqyleskdlekeeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgt 276 
                        l++  + ++ +YW+++l+g +p  +Lp d  +++++   a  ++++   e ++ l ++ + +g t+ ++l+ a+gllLs ytg++++ +g 
    EEA19299.1 7581 ----LQQSSVAEDLNYWKKYLSGAEP-CNLPGDFSNSQQKPSAALVKKVESVLEDTNDLARFSEIHGFTVANILQVAWGLLLSAYTGSSKVLFGY 7670
                    ....7888999************666.99****44444444443444444445778899************************************ PP

                    EEESSTTCSTCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEEC CS
  Condensation  277 eisgReseikdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeees 371 
                     +sgR  +i+ i++ vG  +n++   + ++++ t  +++++v+++ l+ ++hq+  l ++++ l+l  +     Lf++ +s+          e +
    EEA19299.1 7671 LASGRDAPIEHINELVGPMINMMITSMSLNPDSTVLDVVQQVQDNFLEGFQHQRSSLIDIQHALDLSGE----RLFNSTISYRR-------DEGQ 7754
                    *****************************************************************9997....7********66.......8888 PP

                    CCCSEEECEE...E.....SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTTSBCCC-----HHHHHHH CS
  Condensation  372 qlselklsvssveaeeeskydlsleasetngkltikieYntslFdeetierflerlkelleqviehpeqklselkllsdaekekL 456 
                    q s+l+++ s+++ e+ ++yd++l++  ++++ +++++Y+ s     + + +l+ +++l++ ++++ +++l +l+l+ + + e++
    EEA19299.1 7755 QTSSLGIE-STSG-EDPTEYDVNLHIGWKGKSAKFTLQYAPSYLTADSATHILRNFEHLVQVIVRNEKTRLMDLELVAPHDLEQI 7837
                    88888888.5566.99************************************************************999887776 PP

  == domain 12  score: 112.8 bits;  conditional E-value: 3.5e-36
                    EEEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T..TSSSHH CS
  Condensation    2 qdeyplspaQkrmwflekleeessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvileerevelevleisdleeseee 96  
                    +d+yp +p+Q+++  +   +++s +y    ++k+ + +d +r++++++   e   +LRt+++   + e +Qv+  e  ve+  ++isd+ ++   
    EEA19299.1 8507 EDVYPSTPLQEGLMAI--TSKASGHYTRHQIFKMAPFIDMDRFKSSWERAAELASILRTRIILGPQSESLQVVIREG-VEW--THISDV-GNY-- 8593
                    799*********5443..344579***************************************99*******99764.455..667743.333.. PP

                    HHHHHHHHHHHTC--SCCCS-SEEEEEEESSTT.EEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHH CS
  Condensation   97 eaieefaqkdlqepfdLekgpLfraalfkiaen.rlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskd 190 
                      i ++       +++L +  L+r a+ +   +   ++++s+HH i DG+Sl+ +++  ++lY   ++++  p  ++tp+ +++      l+++d
    EEA19299.1 8594 --IASLDAH----SMQLGS-RLVRYAIAQSPITrDRYFIWSIHHSIYDGWSLQKIFQLVSQLY---AQQS--PF-EITPFNRFVRF----LQEAD 8671
                    ..6666664....555543.4555555554433056899************************...3333..44.46779999887....889** PP

                    HHHHHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEESSTTCS CS
  Condensation  191 lekeeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisgResei 285 
                    + ++ +YW  ql g    l +p     +a +    ++       +t  kl ++  + + t  ++   a++l++s+  +++di++g + sgR+ ++
    EEA19299.1 8672 MTTTHDYWCLQLGG-GSPLGFPVH-SGTAYNAKPIKKA------STNLKLSNI--SGSFTAATLIRGAWALAISRQFKSEDIIFGAPLSGRTAPV 8756
                    *************9.454888888.2222222221222......233344444..5678999*******************************99 PP

                    TCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEECCCCSEEECE CS
  Condensation  286 kdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeeesqlselklsv 380 
                     +i +m+   + t+P+ri+++++ +  +++ ++++++ ++ p +  +l+ +++ ++   +++ + L+++ ++++   ++ +++++s++ +l+++ 
    EEA19299.1 8757 PGILDMIAPTLTTVPVRIKINPQSSIYDYLVAIQHQATDMIPFEHSGLQVIRQLTKDVCSADLQDLIQHLLVIQP-STEREDKSASIFPGLEIQ- 8849
                    9************************************************************************99.334444444444455554. PP

                    E.....E.....SSEEEEEEE..TTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHS CS
  Condensation  381 ssve..aeeeskydlslease..tngkltikieYntslFdeetierflerlkelleqvieh 437 
                          + +  +y l  + s+  +++ l+++i+Y  ++ ++++ + +le+++++ e++ + 
    EEA19299.1 8850 ---DnrETSFHSYPLVATCSIdsQTEYLEMEIDYDDEVVSSSQTQSLLEQFQHIFEELQKS 8907
                    ...312466779999999999889999*************************999987654 PP

  == domain 13  score: 93.9 bits;  conditional E-value: 2e-30
                     EEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T..TSSSHHHHHHHHHHHHHTC--SCCCS-SEEEEEEE CS
  Condensation    33 lklegeldlerlekalqelierhdaLRtvfleeengepvQvileerevelevleisdleeseeeeaieefaqkdlqepfdLekgpLfraalfk 125  
                     + ++g  d+ r ++++ eli+rh++LRt +    +++ vQ il + e e+ v      ++ +  + +e +++ d+ ++ +L + p +++a+++
    EEA19299.1  9623 FDADGICDIPRWRRSILELIRRHEILRTAYAFI-EQDLVQAILRHYEPEVAVYTTI--DTIN--QFTEDLLRHDMHKHPQLGR-PFVQFAIVQ 9709 
                     55677789999*******************655.9********9999999555555..3332..3467777777777777765.666666666 PP

                     .SSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHHHHHHHHHHHHHHH......S.---BSS CS
  Condensation   126 .iaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskdlekeeaYWseqlegelpvlq.Lpkdka 216  
                      ++ +++ +++++ H   D++S++ ++++l ++Y      e+lp+ +  ++++y+ +++   es    k++++W+ +l+g + +++ +p+   
    EEA19299.1  9710 nRQVEKHRVIFRISHGEYDAISMSYFIESLKSIY------EDLPNAEYGHFSRYVRALSLHPES----KSREFWRSLLKG-ATMTEiVPRV-- 9789 
                     257799****************************......8888888888*******6665555....59**********.6666645555.. PP

                     ---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEESSTTCSTCHHC--SS-EEEEEEEEE--TT- CS
  Condensation   217 rpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisgReseikdiermvGlFvntlPlridvkeak 309  
                         +s   ++l++  + ++e    ++a   ++t+  v  aa++ +Ls+yt ++d+ +g ++sgR+  + ++e++ G  vn++P+ri ++ + 
    EEA19299.1  9790 --DIDSQVPSELRFCAPRTVEI---STALPDSITVACVVKAAWAFVLSQYTTTSDVLFGEIVSGRNLTDHRMEKIAGCCVNIVPVRIAMQSDW 9877 
                     ..33333445667766555553...5778999************************************************************* PP

                     BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEECCCCSEEECEE....E.....SSEEEEEEETT CS
  Condensation   310 tfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeeesqlselklsvssve.aeeeskydlsleasetn 401  
                     t  +l++ +++++ + +p + ++++++ ++++ +   s +  f++ ++  +     +  +  +l + +++vs +   e     d++++ + ++
    EEA19299.1  9878 TILDLLRFMQDQQISRLPFECFGFQKILQECADPPF-STH--FTSRINHRS----GDFDTGLTLGGKTYTVSGSLaPEAGDIADIAITSTAST 9963 
                     ***************************999996663.333..666666655....66777777776666665555445555667778888888 PP

                     SSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTT CS
  Condensation   402 gkltikieYntslFdeetierflerlkelleqviehpe 439  
                     gk++i i Y  ++      e+fle l ++++ +i++  
    EEA19299.1  9964 GKMEILIGYIGDRVPVGVAEMFLESLSNTVDHFINKSR 10001
                     99999999988888888888888888888888776654 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   0.0   3.5e-09   1.6e-05       1      64 [.      55     117 ..      55     118 .. 0.96
   2 !   37.7   0.0   4.3e-13   1.9e-09       1      64 [.    1579    1641 ..    1579    1643 .. 0.97
   3 !   31.7   0.0   3.3e-11   1.5e-07       3      67 .]    3120    3183 ..    3119    3183 .. 0.97
   4 !   41.3   0.0   3.3e-14   1.5e-10       1      64 [.    4208    4270 ..    4208    4272 .. 0.97
   5 !   38.5   0.0   2.4e-13   1.1e-09       1      67 []    5745    5810 ..    5745    5810 .. 0.96
   6 !   30.6   0.0   7.2e-11   3.2e-07       3      65 ..    6856    6917 ..    6854    6919 .. 0.96
   7 !   33.0   0.1   1.2e-11   5.6e-08       1      64 [.    8392    8454 ..    8392    8457 .. 0.95
   8 !   41.8   0.0   2.4e-14   1.1e-10       2      65 ..    9486    9548 ..    9485    9549 .. 0.96

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 3.5e-09
  PP-binding   1 eklrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaela 64 
                 e++++++a  l+v  e ++ ++ +   G+DSlla++++++ +e+ g++++ sdl+  +tl++++
  EEA19299.1  55 EQVKDVFAMTLKVKKEKLKMQEAFLAQGGDSLLAIQIVGRCREA-GFQFDTSDLLRANTLEQMC 117
                 579999999***********************************.****************986 PP

  == domain 2  score: 37.7 bits;  conditional E-value: 4.3e-13
  PP-binding    1 eklrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaela 64  
                  +kl++++aevl+ pl +i ++ ++ +lG+DS++a++++++ +   g++i++ ++++ +++ +l+
  EEA19299.1 1579 RKLQQIWAEVLNKPLAAIPVNRSFLSLGGDSISAMQVASRCRSD-GISISVKEIMQTKSILDLS 1641
                  589*****************************************.***************9997 PP

  == domain 3  score: 31.7 bits;  conditional E-value: 3.3e-11
  PP-binding    3 lrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaayl 67  
                  l++++a  l++++  i+ ++++f  G+DS++a++l+  l++     ++++d+f hp l+++a+++
  EEA19299.1 3120 LQDAWAITLRIDANKISTTDHFFRSGGDSVSAMRLVDLLQKN-HMHLSVADIFLHPRLSDMAHHI 3183
                  8899**************************************.7*******************98 PP

  == domain 4  score: 41.3 bits;  conditional E-value: 3.3e-14
  PP-binding    1 eklrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaela 64  
                  ekl++++++vl++pl ++ ++t++ + G+DS++a++++++ ++  g++i+++d+++ ++++el+
  EEA19299.1 4208 EKLQTAWSQVLNIPLHQVPLNTSFVSIGGDSITAMQVVSRCRDN-GIAISVRDILQRKSIQELS 4270
                  589*****************************************.*****************97 PP

  == domain 5  score: 38.5 bits;  conditional E-value: 2.4e-13
  PP-binding    1 eklrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaayl 67  
                  ++lr l+a+vl+ ++e+i   +++f lG+DS++a++l+++ +e   ++i++s +f++p l+++a+yl
  EEA19299.1 5745 RQLRLLWAKVLDKEEESIVTGSHFFRLGGDSVAAMRLVSWAQEV-HLRITVSNIFQYPILSDMAQYL 5810
                  58999***********************************9998.8*******************97 PP

  == domain 6  score: 30.6 bits;  conditional E-value: 7.2e-11
  PP-binding    3 lrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaa 65  
                  l+e++ +vl++pl ++ ++ ++   G+DS++a++++++ +++ ++ + ++d+++ +++ +la+
  EEA19299.1 6856 LQEIWGQVLNLPLHSVPVNRSFLTVGGDSITAMQVVSQCRKR-NILLLVRDILQSKSITDLAR 6917
                  89**************9*************************.******************98 PP

  == domain 7  score: 33.0 bits;  conditional E-value: 1.2e-11
  PP-binding    1 eklrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaela 64  
                  +kl+ l++++l+ ++e i++ +++f  G+DS++a++l+a  ++  ++e+++s +f+ p l+e+a
  EEA19299.1 8392 RKLQGLWSKALKKDPETISARDHFFRSGGDSVTAMSLVALARDI-ELELTVSLIFQSPVLSEMA 8454
                  5899**********************************998887.*****************98 PP

  == domain 8  score: 41.8 bits;  conditional E-value: 2.4e-14
  PP-binding    2 klrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaa 65  
                  +l++++a++l+  ++ i++++++f  G+DS++a++++a+ + + g+ ++++d+f+hp l+++a 
  EEA19299.1 9486 ELQSIWASILHKCVDTIGVHDNFFRSGGDSVTAMRMVAMARNH-GINLTVADVFQHPVLGDMAG 9548
                  799********99999**************************9.*****************996 PP

>> AMP-binding_C  AMP-binding enzyme C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.0     0.039   1.7e+02      12      76 .]    1455    1539 ..    1443    1539 .. 0.63
   2 ?    2.9   0.0     0.051   2.3e+02      45      76 .]    3050    3081 ..    3034    3081 .. 0.88
   3 ?    4.1   0.0      0.02        91       1      76 []    4075    4170 ..    4075    4170 .. 0.75
   4 ?    3.5   0.0     0.032   1.4e+02      15      76 .]    5644    5708 ..    5616    5708 .. 0.70
   5 !   11.4   0.0   0.00011      0.49       1      76 []    6720    6815 ..    6720    6815 .. 0.77
   6 ?    3.9   0.0     0.024   1.1e+02      44      76 .]    8323    8355 ..    8288    8355 .. 0.87
   7 !    7.8   0.0    0.0014       6.4      40      76 .]    9412    9448 ..    9369    9448 .. 0.80

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.039
                     EEEEEEE.-----TTS---EEEEEE--....----..................HHHHHHHHHHHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   12 VaeaaVv.GvpdevkGealvafVvlkd....gsea..................leeeLkahvrkelgpyavpkkvvfvdelpktrsGK 76  
                     V +a V+ +++   kG +lv++ vl+d                             +++ +v +++ +y+vp+   +++++p++ sGK
     EEA19299.1 1455 VLDATVIyAKQGLFKG-RLVGLLVLEDvsedA--TfleflegidiisdrkaaeKVVAIRVYVSENVMEYMVPSLWLLCKSIPLNDSGK 1539
                     6666665344444666.777777775433330..1333344444444444445567888999*************************9 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.051
                     HHHHHHHHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   45 eLkahvrkelgpyavpkkvvfvdelpktrsGK 76  
                     eL+  + ++l++y+vp+  +  + +p+t sGK
     EEA19299.1 3050 ELQNSLFEALPSYMVPSIYIPFSHIPLTSSGK 3081
                     78888899*********8887779*******9 PP

  == domain 3  score: 4.1 bits;  conditional E-value: 0.02
                     HHHHHHHSSTTEEEEEEE-----TTS---EEEEEE--............----..........HHHHHHHHHHHHT-TTTS-SEEEE-S---B- CS
  AMP-binding_C    1 evEsalvshpaVaeaaVvGvpdevkGealvafVvlkd............gsea..........leeeLkahvrkelgpyavpkkvvfvdelpkt 72  
                     e+E  l++h +Va+ ++   +     ++lv+  vl++            +                e+  ++ + l +y+ p + v+++ +p +
     EEA19299.1 4075 EIEHHLLKHHQVANGVITYAQSGSYKSRLVCTLVLHKfscdtlekneirE--IrpedkreaaiQCSEISHYLSQLLTSYMIPTAWVALSTMPVN 4166
                     89999999999999886633333455899999999766666555544431..0344455667778999999999******************** PP

                     TTS- CS
  AMP-binding_C   73 rsGK 76  
                      sGK
     EEA19299.1 4167 DSGK 4170
                     ***9 PP

  == domain 4  score: 3.5 bits;  conditional E-value: 0.032
                     EEEE-----TTS---EEEEEE---....---....HHHHHHHHHHHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   15 aaVvGvpdevkGealvafVvlkdg....sea....leeeLkahvrkelgpyavpkkvvfvdelpktrsGK 76  
                     aa++ +p++     l ++ +++d+    + +    l + ++  + +el++++ p+  v ++ lp  +sGK
     EEA19299.1 5644 AAAIQIPHP----ELYGYNTPADNllpvT-DalteLLNRVQTALSRELPTHMIPELYVPIKHLPIRESGK 5708
                     444445555....4555666654444321.2344566666666688*********9999**********9 PP

  == domain 5  score: 11.4 bits;  conditional E-value: 0.00011
                     HHHHHHHSSTTEEEEEEE-----TTS...---EEEEEE--......----................HHHHHHHHHHHHT-TTTS-SEEEE-S-- CS
  AMP-binding_C    1 evEsalvshpaVaeaaVvGvpdevkG...ealvafVvlkd......gsea................leeeLkahvrkelgpyavpkkvvfvdel 69  
                     e+E  l shp +++a V+  p e  G   ++lva+ + +d      +  +                + ++  + +   l++y+ p +   v++l
     EEA19299.1 6720 EIEHHLRSHPSISDAIVI-YPKE--GpykHRLVALFTAHDftpdadN--EtflpyidqshyaeisqVIDDMSETLSLSLATYMMPTAWLPVARL 6808
                     8*****************.4444..444699****998764444431..1455555556666666777777777788***************** PP

                     -B-TTS- CS
  AMP-binding_C   70 pktrsGK 76  
                     p + sGK
     EEA19299.1 6809 PTNDSGK 6815
                     ******9 PP

  == domain 6  score: 3.9 bits;  conditional E-value: 0.024
                     HHHHHHHHHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   44 eeLkahvrkelgpyavpkkvvfvdelpktrsGK 76  
                      +L+ ++ + l++y+vp+ +v ++++p ++sGK
     EEA19299.1 8323 VNLQTKLLDSLPAYMVPSLFVPLKKIPVNQSGK 8355
                     5677777789**********************9 PP

  == domain 7  score: 7.8 bits;  conditional E-value: 0.0014
                     --HHHHHHHHHHHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   40 ealeeeLkahvrkelgpyavpkkvvfvdelpktrsGK 76  
                     +++ ++L+a + ++l++y+vp     ++++p+t sGK
     EEA19299.1 9412 RETMAKLQAALHDTLPAYMVPALYLPLKQVPQTSSGK 9448
                     3378999999999***********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (10022 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       575  (0.0320709); expected 358.6 (0.02)
Passed bias filter:                      525  (0.0292822); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 2.90u 0.40s 00:00:03.30 Elapsed: 00:00:00.69
# Mc/sec: 43529.79
//
Query:       EEA19300.1  [L=132]
Description: extracellular guanyl-specific ribonuclease RntA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.7e-08   34.5   0.1    3.6e-08   34.0   0.1    1.2  1  Ribonuclease  ribonuclease


Domain annotation for each model (and alignments):
>> Ribonuclease  ribonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.0   0.1     2e-12   3.6e-08      18      89 .]      60     128 ..      44     128 .. 0.80

  Alignments for each domain:
  == domain 1  score: 34.0 bits;  conditional E-value: 2e-12
  Ribonuclease  18 agsgpfryksigGdvfgNregl.LPkkksgyYrEydvntpgekyr....gadRivtg.dgldske..tyytadhyesFve 89 
                    + +p++y        +++eg+ +P++  g+++Ey++ ++ + y     gadR++++ dg+  +   t+++a  y  Fve
    EEA19300.1  60 DHGYPHQY--------NDNEGFdFPVS--GPWYEYPILSSFNVYTggqpGADRVIFNgDGE-YAAliTHTGASNYDGFVE 128
                   22266666........899******99..***********9999888889*******7777.33368***********85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (132 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       466  (0.0259914); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.32s 00:00:00.88 Elapsed: 00:00:00.54
# Mc/sec: 738.47
//
Query:       EEA19301.1  [L=392]
Description: tartrate-resistant acid phosphatase type 5 precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.9e-09   36.1   0.2    1.1e-08   35.8   0.2    1.3  1  Metallophos    Calcineurin-like phosphoesterase
  ------ inclusion threshold ------
      0.025   14.8   0.0      0.048   13.8   0.0    1.5  1  Metallophos_2  Calcineurin-like phosphoesterase superfamily d
        0.4   10.8   3.5        4.5    7.4   0.2    2.5  2  Elicitin       Elicitin


Domain annotation for each model (and alignments):
>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.8   0.2   1.9e-12   1.1e-08      22     203 ..     100     297 ..      38     298 .. 0.65

  Alignments for each domain:
  == domain 1  score: 35.8 bits;  conditional E-value: 1.9e-12
                  HHHHHHHHHHTTESEEEEESTSSSSS..........HHHHHHHHHHHHHHHHTSEEEEEC-TTS........CHHHHHHHHHHHHHHH...HHHHEHH CS
  Metallophos  22 lkllddllreekpdlvllaGDlvdrg..........dlekellellaalvkypipvylllGNHe........gfeeellnkygylgif...sepwrsd 98 
                  +++++++ + +++ +++ +GD+++++           +++ +++++++ v ++  +y +lGNH+         fe +l ++y++  +f   +      
   EEA19301.1 100 ANYIEKVCAMKDCSAFISVGDNFYDSgvgftttgvnRFQETWVDMYSQGVYENATWYQCLGNHDivygqagvDFETKLAPLYDDRWYFgteG------ 191
                  4555666555799********7777669999999998888899999999999*************998776655556666666555554443...... PP

                  HCEEETSEEEEEETTE.EEEEEEESE.CEEE.....THHHHHHHHHHHSCHHHHCCHHHHHHHHHHTTCSEEEEEESSESS.CSSSCSCCHHHHHHHH CS
  Metallophos  99 aevfnnlplaslgsgs.lkvlllhGg.spel.....lvsldklgslnleleapepgdewlkdlekrekadwvivlgHsply.rgsgylfgdealedll 188
                     + ++     g ++  ++++++ + ++e      +v  ++ ++  + + +++   ++  +  +++kadw+++  H++   ++  y+   + +   +
   EEA19301.1 192 ---LPYYTYDIVGRDWtATFVVVDSDcFIEKyqkksSVYQNEYTTSCYKTKQTQ--VDFVTQAFAKSKADWKFLQIHHGFLsSSTNYTELWPLVSVAE 284
                  ...333333333333354555555554222222222111111222222222222..44555556668**************64444444444444335 PP

                  HHTTESEEEEESSSS CS
  Metallophos 189 kkygvdlvisGHtHv 203
                  + +g  +v+ GH+H+
   EEA19301.1 285 QHNG--VVLNGHDHC 297
                  5555..9999****7 PP

>> Metallophos_2  Calcineurin-like phosphoesterase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   8.1e-06     0.048      55     153 ..     156     321 ..      98     332 .. 0.63

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 8.1e-06
  Metallophos_2  55 laVrGNnD.................................................eev.veedvlreaaelgtdl......peeaelel..... 89 
                    + + GN+D                                                 + + ++e+ ++++  +++++      +++ ++++     
     EEA19301.1 156 YQCLGNHDivygqagvdfetklaplyddrwyfgteglpyytydivgrdwtatfvvvdS-DcFIEKYQKKSSVYQNEYttscykTKQTQVDFvtqaf 250
                    5566666666666666666666666666666666666666666666666666666541.2244444444444444444444443444444445556 PP

  Metallophos_2  90 ....agekvlliHgdpl...gvkdalaellkeaeegsdvvvcGHtHvpevekeggvlvvnPGsvgeprdgd 153
                        a++k+l iH+  l       +l +l++ ae+ + vv+ GH H +     +++ +v  G++g p  gd
     EEA19301.1 251 akskADWKFLQIHHGFLsssTNYTELWPLVSVAEQHNGVVLNGHDHCAAHYVGNNTNFVLSGAAGYPEVGD 321
                    6666999*999999866444333334445555555555**********9999999********99997665 PP

>> Elicitin  Elicitin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.2   0.00075       4.5      22      57 ..      80     117 ..      61     122 .. 0.81
   2 ?    3.7   0.4     0.011        66       2      39 ..     215     253 ..     214     260 .. 0.71

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.00075
    Elicitin  22 tCatdsgys..llpvtatptdeqvaamCassaCqklla 57 
                  C t+ + +   +++++ +t++ ++++Ca ++C++ ++
  EEA19301.1  80 DCDTGDRAAaqNASAAQVSTANYIEKVCAMKDCSAFIS 117
                 5665544444467889999***************9886 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.011
    Elicitin   2 CsstelvaalasllsnaelatCatdsgys..llpvtatpt 39 
                 C +++ + + +s+++n+++++C ++++ +  +++ + + +
  EEA19301.1 215 CFIEK-YQKKSSVYQNEYTTSCYKTKQTQvdFVTQAFAKS 253
                 77777.889999**********988777733555444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (392 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       639  (0.0356406); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.48
# Mc/sec: 2443.40
//
Query:       EEA19302.1  [L=171]
Description: integral membrane protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    0.00018   21.8   3.9    0.00034   20.9   3.8    1.6  1  DUF1772    Domain of unknown function (DUF1772)
  ------ inclusion threshold ------
      0.042   13.8   0.1       0.23   11.4   0.1    2.1  2  Hemopexin  Hemopexin


Domain annotation for each model (and alignments):
>> DUF1772  Domain of unknown function (DUF1772)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   3.8   3.8e-08   0.00034      23     136 ..      46     158 ..      13     159 .. 0.70

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 3.8e-08
     DUF1772  23 l....llkqwrrlfkrg.kavfpplallsalafa.yla..araasrgarllylaaaallllsivpyTllvmvPtNnkLaalk.eedakekedeaevrel 112
                 +    l + ++++f++g  +v+++l+l+  ++ + y++   +  ++++ ++y+a+a+l++      + l++vP+ +  +++  e+d    ++  +  + 
  EEA19302.1  46 KsdfiLPTYFKEFFAAGlPRVVGLLGLTFWTSIGnYYWryDSLVGTRSLRWYIAGASLAA------SHLLFVPLVAPQIRAIvEDD----RSNGTPTSV 134
                 2345577899**************999999999999999655556666666655555544......34444443322222221333....233444558 PP

     DUF1772 113 lerWgrlnlvRavlalaaavlgll 136
                 l++W   +l+R+ ++ +aa+++l+
  EEA19302.1 135 LDEWLNIHLLRTWTVDLAAWACLA 158
                 9******************99985 PP

>> Hemopexin  Hemopexin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1   2.6e-05      0.23      17      34 ..      79      99 ..      78     104 .. 0.81
   2 ?   -0.9   0.0      0.18   1.6e+03      29      43 ..     127     139 ..     123     141 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 2.6e-05
                TTEEEEEETT...EETTTEEE CS
   Hemopexin 17 GdkYWrfdpq...kvepgypk 34
                G++YWr+d+    ++ ++y  
  EEA19302.1 79 GNYYWRYDSLvgtRSLRWYIA 99
                9*******9988888888765 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.18
                 TTTEEEEHHHHSTTS CS
   Hemopexin  29 epgypklisdswpgl 43 
                 + g+p+++ d w  l
  EEA19302.1 127 SNGTPTSVLDEW--L 139
                 5799****9995..4 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (171 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       222  (0.0123822); expected 358.6 (0.02)
Passed bias filter:                      158  (0.00881254); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1132.97
//
Query:       EEA19303.1  [L=347]
Description: glycosyl transferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.2e-10   39.4   0.0    1.7e-09   38.2   0.0    1.5  1  Gly_transf_sug  Glycosyltransferase sugar-binding region cont
  ------ inclusion threshold ------
      0.031   12.9   0.1          6    5.4   0.0    2.1  2  Tweety          Tweety


Domain annotation for each model (and alignments):
>> Gly_transf_sug  Glycosyltransferase sugar-binding region containing DXD motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.2   0.0   1.9e-13   1.7e-09       4      87 ..      96     171 ..      94     180 .. 0.86

  Alignments for each domain:
  == domain 1  score: 38.2 bits;  conditional E-value: 1.9e-13
  Gly_transf_sug   4 ekkaieslakahpdyqvvvlskelekvrvaildlefllsd.tpwfeeakkllplfialsDllRlaiLykyGGiYlDtDvivlksl 87 
                     +  a ++++k+h ++   +++++           e+l+++  p ++++ +++ +++++ D+lR+++L kyGG+ lD D  + +sl
      EEA19303.1  96 WLGARDECIKYHLNWTAYIWDDNAA---------EKLVKEeFPHLNDMWNNYRYPVERVDALRYMVLQKYGGVVLDFDLACKRSL 171
                     6678899***************988.........5555554788888999999******************************99 PP

>> Tweety  Tweety
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   0.1   0.00068       6.1     195     266 ..       8      77 ..       4      85 .. 0.85
   2 ?    5.4   0.0   0.00067         6     364     400 ..     298     334 ..     291     339 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.00068
      Tweety 195 ldlviClvlllglarkskcllivvsvlgllalvlsWaslglelasavgasDfCvsPdkyvvkqtkeels.sdi 266
                 l++v+C+vlll    +  +l +  +++ l++l   W  ++++  ++    Df v  ++y v+qt++ +s +d+
  EEA19303.1   8 LLIVVCAVLLLS---QRWWLPLGNTLFNLVSLSTRWRHASAQSWVSKDRDDFDVTFASYPVNQTTAGSSyQDL 77 
                 667888888764...566777999**************************************99987765665 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.00067
      Tweety 364 ylllfsllaallltilvcsvpraWkllrkrdkdyddv 400
                  l+ +s++a+l+lt+  c+  r   + +kr+k  +d+
  EEA19303.1 298 VLVCMSFVASLMLTVYYCTCLRRRRYAAKRNKIIADK 334
                 57889*****************999999999877765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (347 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       414  (0.0230911); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.23s 00:00:00.70 Elapsed: 00:00:00.40
# Mc/sec: 2594.27
//
Query:       EEA19304.1  [L=309]
Description: glycan biosynthesis protein (PigL), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.4e-23   82.1   0.0    7.2e-23   81.7   0.0    1.2  1  PIG-L     GlcNAc-PI de-N-acetylase


Domain annotation for each model (and alignments):
>> PIG-L  GlcNAc-PI de-N-acetylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.7   0.0     4e-27   7.2e-23       1     130 [.      65     189 ..      65     190 .. 0.97

  Alignments for each domain:
  == domain 1  score: 81.7 bits;  conditional E-value: 4e-27
                 EEEESSTTHHHHHHHHHHHHHHHT.T-EEEEEECE--TT---STTTTHH-HHHHHHHHHHHHHHHHCTE..EEEEECC...CBTT-STTS-CHHHHHHH CS
       PIG-L   1 llvlAHpDDellfaggtiaklvaa.gvevkivcltaGdagsplatleekeelaeiRekEaraaakhlgvadedvffld...fpDgslesydedellddl 95 
                 ll++AHpDDe+lf+++ i++  ++  v+ ++++l++G+ +          +l+e R+ E +a++++lg++d+++++l+   ++D+  + +d + +++ l
  EEA19304.1  65 LLITAHPDDESLFFSPSILHNSEKpHVNRHLLVLSSGNFN----------GLGEHRRTETKASCAALGIRDDNCVILNdkdLQDNPRQWWDDSIIEKIL 153
                 79*****************999877***************..........************************************************* PP

                 HHHHHHH--SEEEEE-TTTT.H-HHHHHHHHHHHHH CS
       PIG-L  96 aklieryrPdvvltldpegd.dhpDHtavasaavaa 130
                  ++i++ + d+++t+d  g  +h++H++v+++++++
  EEA19304.1 154 GEYIKKWNIDLIITFDHYGVsGHVNHRSVSKGVKKF 189
                 *******************9**********999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       559  (0.0311785); expected 358.6 (0.02)
Passed bias filter:                      454  (0.0253221); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.23s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 2246.01
//
Query:       EEA19305.1  [L=293]
Description: hypothetical protein PMAA_001050 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0025   17.5   0.0      0.003   17.2   0.0    1.2  1  DAO       FAD dependent oxidoreductase


Domain annotation for each model (and alignments):
>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   1.7e-07     0.003     141     212 ..     159     227 ..      86     260 .. 0.73

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 1.7e-07
                 EEEEHHHHHHHHHHHHHHTT-EEEESECEEEEEEEETCEEEEEEECT.EEEEEEEEEEE--GGGHHHHHTT.CT CS
         DAO 141 gqvdpakltaalaraaealGveilegtevtgleeedgkvwgverttp.gendaadavVnaaGawsdllgll.ke 212
                  +++++ l  al++aa+++Gv+i+++ +v + + +    ++     + g ++  d +V a G+ s  ++ll ++
  EEA19305.1 159 YRIHCHDLNVALLDAAKRAGVTIHTKQRVLSYDFD-AHSATM----EaGKTRMLDLIVCADGIKSIASPLLtGQ 227
                 569****************************9553.223344....3376666788999999997432444433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (293 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       433  (0.0241508); expected 358.6 (0.02)
Passed bias filter:                      360  (0.0200792); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.29s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 1929.69
//
Query:       EEA19306.1  [L=480]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.4e-20   73.3   0.0    2.1e-19   69.5   0.0    2.2  1  AATase          Alcohol acetyltransferase
     0.0039   17.0   0.0     0.0059   16.4   0.0    1.3  1  WES_acyltransf  Wax ester synthase-like Acyl-CoA acyltransfer


Domain annotation for each model (and alignments):
>> AATase  Alcohol acetyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.5   0.0   2.3e-23   2.1e-19       2     499 ..      15     473 ..      14     474 .. 0.74

  Alignments for each domain:
  == domain 1  score: 69.5 bits;  conditional E-value: 2.3e-23
      AATase   2 lGslEkyfvvrnrqklysnfsvyae..lnkevdkeq..LalalrslilknpiLaaniipkkfpeheayyssdeyyskPfpkeDyvkviekiklddvvln 96 
                 lG lE  + +++++ +++n+ v+a   +n+ v   q     al ++i+++ iL  + i              e + +P     y   +++i+l+dvv  
  EEA19306.1  15 LGLLERHSTAQHSLGYHNNIAVSALyvYNSTVPTLQepVFSALENVIQEHAILGVIPIG-------------EDTPNP-----YFARLPRIDLQDVV-- 93 
                 89*********************972257777654433789************987773.............446677.....9999**********.. PP

      AATase  97 eqpeysellekileeykdddekvdeelnells...elvipvgdpkkPlwrlivlpsaddkk..kwkkfv..fitdHllfDGisgvnffkdlleelekik 188
                    e         e ++  + ++d+el e l+   +  ++    + P wrl++l + +  +  +  +f+  f+  H + DG+sg+ f++     l   +
  EEA19306.1  94 TFVER-------KEAWNP-NAEIDSELDETLErehNRDFKQRYGELPFWRLLILHETSAVNagNQSRFIacFVVHHAIGDGLSGMAFHRSFFSALTSPS 184
                 33333.......344444.444454444444311134455556678**********999886666778999***********************99988 PP

      AATase 189 qdnalkkdevildyekdveelekLPkpieekvdyrpsllalpk..lllvsfiasklnfkks.eekpltkehsavqksnkshqiilkispeevkkiraki 284
                 + +           + +v+    +P   ++ +    +l  lp+  +++++ + ++l ++++       +++ + +    s+ +++ +s +  + i + +
  EEA19306.1 185 EVQT----------STTVTPRLVIP-SQKDLIPGLEALHPLPIsvSFILGTVWREL-MPRWsGTVWTAENITENPYMRRSRYKSFTLSASRTADIIKIS 271
                 8777..........44444222333.222333333333333221134444444443.344421222222333444456667789*************** PP

      AATase 285 kknvhgkatlTpflqavffvalyklgklfkeknsevsidvaipvntRrylpedeevrdsykYgt..vvggseFsylissldieedskeklwelveeyhk 381
                 + +   ++t+T  +++++ +++ +   l+k+      ++va p++ R+ lp+d+   d+++ gt  +  ++e++  is +    +++  +w+ + +   
  EEA19306.1 272 RGK---NTTVTGAIESILAYTVFNQ--LPKKY---TILKVAGPISLRSVLPKDQV--DDNSIGTwsNSYVQEHNRPISGSVD--EKYSYIWNEAIKVRA 358
                 ***...*************999884..55543...579***************99..9999998224456778888887665..566799****99999 PP

      AATase 382 rlseslsngkelkglgtlildlllkyv.nidkllkkkilktkrstaevsNlGlfsq...eeeskykvkdliFsqaagslknafslnvistnsgGlnlsl 476
                  ++       el + g +i   llk v + +k+ +k+i k ++  +e+sNlG fs     e+s++kvk ++Fsqa   +  ++ + +++ ++  ln+  
  EEA19306.1 359 MITG------ELAKEGRNIRTGLLKLVgDSHKFFQKNIGKPRGESIELSNLGVFSTaktAESSSWKVKKVLFSQAGNVVGSPLEVMMSTGPDSRLNIGF 451
                 9999......44445555555566665499*************************9988899***************9********************* PP

      AATase 477 svvedllseqteseefvallekk 499
                 s +e +++  t++e++++ ++++
  EEA19306.1 452 SWLEGVVE-GTWVESVMEEFKQT 473
                 *9998764.56667887777765 PP

>> WES_acyltransf  Wax ester synthase-like Acyl-CoA acyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0   6.5e-07    0.0059     126     173 ..     150     197 ..     139     279 .. 0.75

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 6.5e-07
  WES_acyltransf 126 ggriAillkvHHAliDGvgglkllarlldldpddpprpeppqvpprdr 173
                     ++r+   + vHHA+ DG++g++  +++ ++  ++++++++++v pr  
      EEA19306.1 150 QSRFIACFVVHHAIGDGLSGMAFHRSFFSALTSPSEVQTSTTVTPRLV 197
                     567777788*******************************99877764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (480 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       378  (0.0210832); expected 358.6 (0.02)
Passed bias filter:                      359  (0.0200234); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 3325.63
//
Query:       EEA19307.1  [L=552]
Description: cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.1e-36  123.7   0.1    1.2e-35  123.2   0.1    1.2  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.2   0.1   6.6e-40   1.2e-35     193     456 ..     247     541 ..     184     548 .. 0.82

  Alignments for each domain:
  == domain 1  score: 123.2 bits;  conditional E-value: 6.6e-40
                 CCCHHHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHC.TTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        p450 193 llfpllkylptkllrklkeavkklkdlldklieerretldsakksrrdfldalllak.kekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLa 290
                 l  p+l+   ++++r + +++  + +   +  + ++e+ +++ + ++d l+ l+++  k+k+ + +l+   ++  +l l + +++Tts  ++ a++++ 
  EEA19307.1 247 LASPILQLRNNHHFRVCARICVPVVQQRIRNTRAKQEDPSYKWEPPVDALQWLVEECiKAKDPK-ELDPILITRRLLLLNMVAIHTTSISITHAILNIN 344
                 334555556666666666666666665555556666666666789***********98788887.*******************************998 PP

                 HS...HHHHHHHHHHHHHHCCTTT.T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS....CEEETT.....EEE-TT-EEEEEHHHHHT-TTT CS
        p450 291 kn...PevqeklreEidevlgdkr.eptyddlqklpyldavikEtLRlhpvvplllpRevtk....dvvirg.....ylipkGtevivnlyalhrdpev 376
                 ++    ev   lreE ++ lg+++   t + l++   ld +i+E++R  ++ p+++ R+v +    d  i+       ++p G +  ++ +++hrdpe+
  EEA19307.1 345 TYehsEEVITSLREECNRLLGENDgVWTKAALNDALRLDSTIRESMRCDDLEPFSTGRMVVHpngiD--INTaagssIHVPHGVTLCLPSHGIHRDPEF 441
                 7622358999**********7666699**********************************955332..22244589********************** PP

                 SSSTTS--GGGGB-TTS.......................CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGEEESSCSS CS
        p450 377 fpnPeeFdpeRFldekg.......................nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdpppileksgl 452
                 ++ P eF+p RF+d ++                            s+ +l+FG G+++C+G+ +A  e+kl+la +Lqn+++e    +++pp+   +g 
  EEA19307.1 442 YDSPLEFQPFRFSDPREkflklqmkaqtdmqtaldlkttsL-VTTSDTYLAFGHGRHACPGRFFAAQEMKLMLAYVLQNYDIEK--LKEKPPSTMLMGT 537
                 ************************************99853.479**************************************5..5555555555444 PP

                 EEES CS
        p450 453 llpp 456
                  +p+
  EEA19307.1 538 NVPN 541
                 4444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (552 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       334  (0.018629); expected 358.6 (0.02)
Passed bias filter:                      310  (0.0172904); expected 358.6 (0.02)
Passed Vit filter:                         5  (0.000278878); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3894.60
//
Query:       EEA19308.1  [L=2534]
Description: polyketide synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.3e-70  236.6   0.0    6.2e-70  235.7   0.0    1.5  1  ketoacyl-synt    Beta-ketoacyl synthase, N-terminal domain
    6.1e-62  208.7   0.1      2e-61  207.0   0.1    2.0  1  KR               KR domain
    1.1e-51  175.8   0.0    1.9e-51  175.1   0.0    1.3  1  PS-DH            Polyketide synthase dehydratase
      5e-49  167.5   0.0    8.5e-49  166.8   0.0    1.3  1  Acyl_transf_1    Acyl transferase domain
    1.8e-38  131.2   0.0    4.7e-38  129.8   0.0    1.8  1  Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
    2.1e-19   70.1   0.0    8.2e-19   68.2   0.0    2.1  1  Methyltransf_12  Methyltransferase domain
    3.7e-19   70.1   0.0    2.3e-17   64.3   0.0    2.8  2  ADH_zinc_N_2     Zinc-binding dehydrogenase
    1.1e-18   67.5   0.1    7.4e-18   64.8   0.1    2.5  2  ADH_zinc_N       Zinc-binding dehydrogenase
    1.2e-15   57.5   0.2    3.3e-15   56.1   0.2    1.7  1  adh_short        short chain dehydrogenase
    5.7e-13   49.3   0.0    1.7e-12   47.8   0.0    1.8  1  KAsynt_C_assoc   Ketoacyl-synthetase C-terminal extension
    3.7e-11   43.6   0.0    2.5e-10   40.9   0.0    2.6  1  Methyltransf_25  Methyltransferase domain
    1.2e-09   38.0   0.0    3.5e-09   36.6   0.0    1.7  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    5.5e-09   36.6   0.0    7.3e-08   33.0   0.0    3.0  2  Methyltransf_11  Methyltransferase domain
    1.2e-08   35.2   0.0    3.1e-08   33.8   0.0    1.8  1  PP-binding       Phosphopantetheine attachment site
    4.5e-08   33.1   0.0      1e-07   32.0   0.0    1.5  1  Methyltransf_23  Methyltransferase domain
    5.7e-08   32.4   0.0    3.3e-06   26.6   0.0    3.1  3  Ubie_methyltran  ubiE/COQ5 methyltransferase family
    7.8e-06   25.8   0.0    2.5e-05   24.1   0.0    1.9  1  Methyltransf_31  Methyltransferase domain
    0.00025   20.9   0.0     0.0015   18.3   0.0    2.1  2  Methyltransf_16  Lysine methyltransferase
     0.0013   17.8   0.0     0.0029   16.7   0.0    1.5  1  3Beta_HSD        3-beta hydroxysteroid dehydrogenase/isomeras
  ------ inclusion threshold ------
      0.048   13.0   0.0       0.11   11.9   0.0    1.5  1  Thiolase_N       Thiolase, N-terminal domain
      0.081   12.2   0.2       0.39   10.0   0.1    2.1  2  AlaDh_PNT_C      Alanine dehydrogenase/PNT, C-terminal domain
      0.098   11.7   0.0        0.2   10.7   0.0    1.4  1  DREV             DREV methyltransferase


Domain annotation for each model (and alignments):
>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  235.7   0.0   7.6e-73   6.2e-70       2     253 .]      33     283 ..      32     283 .. 0.96

  Alignments for each domain:
  == domain 1  score: 235.7 bits;  conditional E-value: 7.6e-73
                    --EEEEEEEEEBTTBSS.HHHHHHHHHTT---EEES-TTSSCGTTSBTSSTTEEE-BSS.EEE..S..TTEGGTTSTHHHHHHHCTS-HHHHHHHH CS
  ketoacyl-synt   2 epvaivGmgarfPggnd.veefwelLlegrdaiselpadrwdadklydpparaagkiktklggfld..vddfdpeffgispreaeamdpqqrllle 94 
                    ep+aivG+g+r+Pgg + ++++w+lL +g++a +++pa+r++ ++++ p+    g+++t+ g fl+  +++fd++ffgi p ea+a+dpqqrllle
     EEA19308.1  33 EPIAIVGVGCRLPGGASsPSKLWDLLAAGKSAWGPFPANRFSHTGFHSPSGLKNGTTNTNGGHFLEedIAAFDAAFFGIRPMEATAIDPQQRLLLE 128
                    79**************99************************************************99**************************** PP

                    HHHHHHHHHTS-HHTCTTGGEEEEEEESSTHHHHHHHHHHHTTGGGSCTTHHHHHSTTHHHHHHHHHHT--SSEEEEESGGGHHHHHHHHHHHHHH CS
  ketoacyl-synt  95 aawealedagltpeeldgsrvgvfiGvgagdyaalaaldedgsevkaspkavgavlanviagrisyalglrGpsvtvdtACsSslvavhaavqslr 190
                    +a+ea+e+ag+t e+l gs++gv++G   +dy++  +l++d++   a+ +++g+  +++ ++r+sy ++ +Gps+tvdt Cs+s va+h avqslr
     EEA19308.1 129 VAYEAFENAGITSEQLWGSNTGVYVGQWTSDYNE--VLSRDTN-FPAFYQTTGT-GPAISSNRLSYYYNTKGPSFTVDTGCSASMVALHSAVQSLR 220
                    ********************************76..6666664.4455558887.***************************************** PP

                    TTS-SEEEEEEEE---SHHHHHHHHHTTBB-TTSGGGTTBTTB-SB-BB-EEEEEEEEECHHH CS
  ketoacyl-synt 191 sgeadvalaGGvellltpeavagfsaagllspdgrckafdpkadGfvlGEGvGavvLkrleda 253
                    +ge d  ++ Gv+l+l p+ +   s+++++s++g++ +fd++a+G+ +GEG+  vv+++l+ a
     EEA19308.1 221 TGETDRSFVAGVNLTLDPQRYTYQSQLKMFSNEGKSFPFDERANGYGRGEGCTGVVIQTLSSA 283
                    **********************************************************99876 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  207.0   0.1   2.4e-64     2e-61       1     178 [.    2160    2336 ..    2160    2338 .. 0.98

  Alignments for each domain:
  == domain 1  score: 207.0 bits;  conditional E-value: 2.4e-64
                  SEEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------T CS
          KR    1 gtylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdkll 97  
                  +ty+++GGlGgLG+ ++ w+ae+ga+++v +sRs++ +e++ +l+++ ++lg+ v+v ++Dv d+++++++++e+k++ ppi+G++++A++l+d+ +
  EEA19308.1 2160 ATYIVVGGLGGLGKRIVLWMAERGAKNIVTFSRSGTMNEQALSLMESAKKLGTIVHVKKCDVGDENQLKQVVAELKDNLPPIRGIVQSAMILEDSVF 2256
                  79*********************************************************************************************** PP

                  TT--HHHHHHHHTTTTHHHHHHHHHTTTS--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHHHHHTEEEEEE--B CS
          KR   98 eemtaedleqvlapKvkGawnLhelledesldffvlfSSiagllgsagqanYaaaNaflDalaeyrrsqglpavsinwglw 178 
                  +emt +++  +++pKvkG+wnLh++l+ +sldffv++SS+ +l g+ gq+nY+aa+af+Dala+yr+s+glp+ sin g++
  EEA19308.1 2257 DEMTYQQWSGAVNPKVKGTWNLHNALP-SSLDFFVMLSSAVALGGNVGQSNYSAACAFQDALAHYRNSHGLPTHSINVGAI 2336
                  **************************9.6*************************************************986 PP

>> PS-DH  Polyketide synthase dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  175.1   0.0   2.3e-54   1.9e-51       1     292 [.     959    1259 ..     959    1263 .. 0.88

  Alignments for each domain:
  == domain 1  score: 175.1 bits;  conditional E-value: 2.3e-54
                  BTTB.-EE--.-SS-EEEEEEE-S-SS.TTTSEEETTEEB--TTHHHHHHHHHHHHTS---.......-EEEEEEEE----.B--SS.-EEEEEEEE CS
       PS-DH    1 hpllGsrvrsasdkevvfrnrlrlaelpwLrDHrvdgkvvlPgagylemaleAarqltges......kavelrdvsilkalvlpede.pvevqlsle 90  
                  h+llG+     ++ e+++r+ +rl+elpwLr H v+g++v+P+agyl++a++A++++t  +      k + +r+vs+ +alvl+e+   +e+ +sl+
  EEA19308.1  959 HDLLGTMGGDYNSVEPRWRKFIRLDELPWLRGHIVQGQIVFPAAGYLALAIQAMKEHTFAEspeasiKNYNIRNVSFGQALVLSEGVeDLEINFSLR 1055
                  999976655669******************************************99984444677999******************99********* PP

                  E-TTS-E.......EEEEEEE-SS-TT.EEEEEEEEEE-----...--B--HHHHHHHS-SEE....E-HHHHHHHHHHHSEEE-GGG--EEEEEEE CS
       PS-DH   91 peedgad...rawvefeifSregggeewtehatGtvrlaegaa...aaavdlealqarcaepaslrsvssaefYerlaargleyGpsFqglralwrg 181 
                  p+  +a    ++w ef++f+++++++ wteh++G + ++ +++   ++  + e+ + +++   s+r+++++++Y   ++ gl++ + F ++ ++ ++
  EEA19308.1 1056 PQVHSARkssKNWSEFRVFTVNADNA-WTEHCRGLINADLTSEgdlDKIISTEDQKLHAQLIQSGRDINPKKLYFLAKDLGLDWASPFDNVIDVKTT 1151
                  **66666999**************98.**********99988877755566666666667777889999**************************** PP

                  TTEEEEEE---GGGSSTTTT-SB-HHHHHHHHH.HG..GG----------EEEEEEEEEEE-S.....-BTS--EEEEEE----SS-EEEEEEEE-. CS
       PS-DH  182 dgealaelrlpeelaggesayvlhPallDaalQ.llaaalsaeaekadaaylPvaierlrvyr..pssaageelwvharleeegarsivadltlvd. 274 
                  +g+a a+++ ++e a   s+y++hPa+lDa+l  +l+a+l   +++ +++++P++i+++++++  +   ++++l+++a+++     ++++d+ ++d 
  EEA19308.1 1152 QGSAIATVKPSDEDA---SPYLIHPAVLDACLFhSLYAVL-IFEDNFKETVVPTFIKKMTISGniD--MSTKNLTCYAHRTTG---QLTYDIGIFDn 1239
                  **********98877...68***********765999988.5789******************643..56899******9764...79********6 PP

                  SS..-BEEEEEESEEEEE-- CS
       PS-DH  275 ed..Grvvaeieglrlrrve 292 
                  e+  G+v+++ + ++ +r++
  EEA19308.1 1240 ETqpGKVILQASTVTATRLP 1259
                  22559*******99999986 PP

>> Acyl_transf_1  Acyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  166.8   0.0     1e-51   8.5e-49       2     303 ..     571     893 ..     570     907 .. 0.88

  Alignments for each domain:
  == domain 1  score: 166.8 bits;  conditional E-value: 1e-51
                    EEE--TT---TTTTCCHHHC-HHHHHHHHHHHHHCCHHHT--..H.HHHHHS--TTGGGSHHHHHHHHHHHHHHHHHHHHHTT-TTSEEEE-TTHH CS
  Acyl_transf_1   2 fvfsGqGsQwaGMGmeLlktskafaaviaradeafksqygfs..v.ldvlrnnpeglldaiqfvqpaLaavqialaellkskGvrpaavvGHSlGE 94 
                    fvfsGqG+Q aGMG eLl + + f  +i+ra + +k+  g s  + +++l+++++  +d+ +++qp  +a+q+ala+ l   G  p  v+GHS GE
     EEA19308.1 571 FVFSGQGAQYAGMGSELLGKWPSFTRSINRAGQQLKE-IGCSwdLtTELLKSAETTRVDEPEVAQPLSTAIQLALADSLAELGILPSFVAGHSSGE 665
                    9************************************.7766334379************************************************ PP

                    HHHHHHCCSSSHHHHHHHHHHHHHHH....HHHT.S-EECCEECS.....HHHHHHH....TT.EEEEEEECCCCECCEEHHHHHHHHHHHHHCC. CS
  Acyl_transf_1  95 lAaavvagalsseeallavvlrsrlm....mqla.gpgdmaavel....aeeeeklr..cqddvvgavansprrvvisgsqealrelvervskeg. 178
                    + aa+ a a+s e+a+ + + r+rl     ++++  pg+m+av++    ++e+ k +   q ++  a+ nsp++v++sg  +a++ l e ++ ++ 
     EEA19308.1 666 IGAAYCAKAISFEDAMTVSYHRGRLAsvlrKRVSdCPGGMLAVGEspeaVAEKIKEIgdAQKRLRIACFNSPSSVTVSGDDDAIELLQEVLGDADi 761
                    ***********************9863333677789*********997644455555457889********************************7 PP

                    .CCEEECCCEECTTCCCCCCCCHHHHHHHHCCCHH..CHHTTBEHCCCHHHHHHCHHHHHHHHHHHCHCCHCCHHTTS..SSECC...-CCEECSS CS
  Acyl_transf_1 179 vgalvenvnvavhspqvdaiadalasaladiaprk..pkvakisstsldesserelsaeywvanlrspvrfaeavlsa..aetip...lvfveisp 267
                    +  + ++ + a hs q++ i+ + ++al  i   k  + v  iss++++e   + ++ +ywv+nl+spv+f ea +++  +++++   +v +e+ p
     EEA19308.1 762 FNRKLRTGGAAYHSHQMNLIESEYRAALEGIEGGKtdSSVVMISSLTSEEVGDTIIDRDYWVQNLVSPVQFTEATKKMcqFKSGHkrlDVLLELGP 857
                    8888999**********************9886551166788889999999999***********************9998877733369****** PP

                    SSCCHCCCCCCCHH.GGG-TCCCCCCTEETTSS-HHH CS
  Acyl_transf_1 268 Hslllaalektlks.aedvksatlvGklkrdltdflv 303
                    H +l   + +tl+    d+++    G+lkr++++   
     EEA19308.1 858 HFQLGGPISQTLRTlRGDAAKIPYTGTLKRGTNA-ET 893
                    *************877788888899*****9988.33 PP

>> Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  129.8   0.0   5.8e-41   4.7e-38       2     118 .]     292     409 ..     291     409 .. 0.98

  Alignments for each domain:
  == domain 1  score: 129.8 bits;  conditional E-value: 5.8e-41
                      EEEEEEEEEE--STSSSTSTTHHHHHHHHHHHHHHHT--GGGEEEEE-SS-SSHHHHHHHHHHHHHHHGGGGG.SCTSEEE-THHHH-B-GGGH CS
  Ketoacyl-synt_C   2 avikgsavnsdgahnsltapngeaqaraiekalaeagvdpedvdyveahgtgtplgDpiElealkkvfgekar.kqplavgSvKsniGHleaAa 94 
                      a+i++s +n+dg++ ++  p+g aq +ai+ka+a+ag++  dvdyveahgtgt++gDpiE++a++++++ +++ ++pl +gSvK n+GHle+Aa
       EEA19308.1 292 AIIRNSVLNQDGRTPGISVPSGLAQSAAIRKAYAQAGINLLDVDYVEAHGTGTKVGDPIEAKAIAEALSCQREmDNPLLIGSVKGNVGHLESAA 385
                      899*****************************************************************999999******************** PP

                      HHHHHHHHHHHHHHTEE--BTT-S CS
  Ketoacyl-synt_C  95 Gvaelikvvlalkhgvipptlnle 118
                      G+++++k++l+l++g +pp++n+e
       EEA19308.1 386 GLTGMLKSILMLEKGFVPPQVNFE 409
                      **********************95 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.2   0.0     1e-21   8.2e-19       1      99 []    1429    1534 ..    1429    1534 .. 0.89

  Alignments for each domain:
  == domain 1  score: 68.2 bits;  conditional E-value: 1e-21
  Methyltransf_12    1 LeiGcGtGsllrallekl......pdieytgvDispsaiedakeklakrennnnnnvelealdlldldgg.ssfDlvvasnvlhhlkdirev 85  
                       LeiG+Gt+s++ +ll++l        ++y ++Dis+ ++++ake+l + e+  n +v + ++d  ++    +s+D+++a+nv+h++  i+ v
       EEA19308.1 1429 LEIGAGTASVTLPLLQRLkpddrvLASRYDFTDISAGFFPAAKERLVDFEDIVNYQVLNAENDPVEQGFTpNSYDIIIACNVIHATSRIETV 1520
                       8*********************************************9999877666666655555443336********************* PP

  Methyltransf_12   86 ldnirklLkpgGrl 99  
                       l+n+r+lLkpgG++
       EEA19308.1 1521 LNNVRSLLKPGGKF 1534
                       ************86 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0      0.37     3e+02       6      53 ..    1485    1538 ..    1476    1596 .. 0.75
   2 !   64.3   0.0   2.9e-20   2.3e-17       4     133 .]    2000    2136 ..    1999    2136 .. 0.93

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.37
                    EEETTSTTHHHHH-TT-EEEEEES-H......HHHH.HHHHHHEEEEEEEEE-- CS
  ADH_zinc_N_2    6 vidyrtedfeaatggegvDvvldtvg......gealleaslkvlpggGrlvsig 53  
                    v++ +++ +e+   ++++D+++ +         e+ l +++++l++gG+++ + 
    EEA19308.1 1485 VLNAENDPVEQGFTPNSYDIIIACNVihatsrIETVLNNVRSLLKPGGKFILME 1538
                    34444555557777999*****9977789999677779999999888**97654 PP

  == domain 2  score: 64.3 bits;  conditional E-value: 2.9e-20
                    SEEEETTSTTHH....HHH-TT-EEEEEES-HHHHH.HHHHHHEEEEEEEEE--.--.S-EEE-CHHHCTTT-EEEE--GGG...-....-HHHH CS
  ADH_zinc_N_2    4 devidyrtedfe....aatggegvDvvldtvggealleaslkvlpggGrlvsig.gpplsaallkpakkrkgrsvkyeflfsmkas...aqadil 90  
                    d+++ +r+++f     + tgg+gvDvvl+++ ge + ++s +++++ Gr+v+ig ++ + +al++ ++  k+ ++ y+ +  + a+     +++l
    EEA19308.1 2000 DHFFSSRNTSFYegimKMTGGRGVDVVLNSLSGEMF-RESTNIVAPFGRFVEIGrKDLMDDALMPMEFLLKNVTFAYVDMALVIAKaktLAQRVL 2093
                    7888889888878999999***************99.*******999*******887799999999999**********999888889966677* PP

                    HHHHHHHHHHH----EEEEEEGGGHHHHHHHHHSS--SSEEEE CS
  ADH_zinc_N_2   91 eelaalieeGklrpvvdrvfpleeaaeAhrylesgrarGKiVl 133 
                     ++ +li +G++ pv   v+p++++ +A+r++++g+++GKi+l
    EEA19308.1 2094 HDVIELINAGAIGPVSIMVMPISNLEDAFRLIQAGKHIGKIIL 2136
                    *****************************************98 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0         5     4e+03      56      88 ..    1499    1537 ..    1478    1550 .. 0.65
   2 !   64.8   0.1     9e-21   7.4e-18       1     116 [.    1962    2080 ..    1962    2094 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 5
                  TSSEEEEEESSC......SHHHHHHHHHCEEEEEEEEEC CS
  ADH_zinc_N   56 gegvdvvfecvG......sgatleaalkllkpgGrlvvv 88  
                  ++ +d+++ c        ++++l++  +llkpgG++ ++
  EEA19308.1 1499 PNSYDIIIACNVihatsrIETVLNNVRSLLKPGGKFILM 1537
                  555666444433111223567788888999999998876 PP

  == domain 2  score: 64.8 bits;  conditional E-value: 9e-21
                  HHHHHHHHHHHHTT-EEEEEESSHHHHHHHHH.TT..ESEEEETTTCHHHHHHHHHTTTSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSC.TSS CS
  ADH_zinc_N    1 gvGlaavqlAkalGaeviavdsseeklelakk.lG..adevinykeadlverikeltggegvdvvfecvGsgatleaalkllkpgGrlvvvGg.gkg 93  
                  +vG+aa++lAk lGae++++++s+ k e++ + +G   d+++ ++++++ e i ++tgg+gvdvv++ +  g+++++++++++p Gr+v +G    +
  EEA19308.1 1962 AVGQAAIMLAKYLGAEIFVTVGSDTKKEFLIQkFGipEDHFFSSRNTSFYEGIMKMTGGRGVDVVLNSLS-GEMFRESTNIVAPFGRFVEIGRkDLM 2057
                  69*****************99999999877655**999******776***********************.*********************97555 PP

                  EEEEEHHHHHHTT-EEEEE-SSC CS
  ADH_zinc_N   94 eeefdlrnlllkeksilGsllgs 116 
                  ++ + ++ +llk++++  + ++ 
  EEA19308.1 2058 DDALMPMEFLLKNVTFAYVDMAL 2080
                  55577777889998887666665 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.1   0.2     4e-18   3.3e-15       3     177 ..    2162    2336 ..    2160    2352 .. 0.87

  Alignments for each domain:
  == domain 1  score: 56.1 bits;  conditional E-value: 4e-18
                  EEEESTTSHHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHT...TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGG CS
   adh_short    3 vlvtGassGIGraiakelakeGakvvv.vdrseekleevakelkee...gakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfse 95  
                   +v+G+ +G+G+ i+  +a++Gak +v ++rs    e++++ ++++   g+ +++ ++Dv d+++++++v++ +++l ++  +v+ A i +++ f e
  EEA19308.1 2162 YIVVGGLGGLGKRIVLWMAERGAKNIVtFSRSGTMNEQALSLMESAkklGTIVHVKKCDVGDENQLKQVVAELKDNLPPIRGIVQSAMILEDSVFDE 2258
                  58*************************8888876666666665555555889********************************************* PP

                  CSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHH.HHHGGGTEEEEEE CS
   adh_short   96 lseeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrsla.kelaptgirvnav 177 
                  ++ ++w   ++  ++g+ +l  a+   ++       v  sS +++ ++ g++ YsA+ a+ ++l++    + l +++i+v a+
  EEA19308.1 2259 MTYQQWSGAVNPKVKGTWNLHNALPSSLD-----FFVMLSSAVALGGNVGQSNYSAACAFQDALAHYRNsHGLPTHSINVGAI 2336
                  *********************99888877.....89********************999888888755414455555777665 PP

>> KAsynt_C_assoc  Ketoacyl-synthetase C-terminal extension
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.8   0.0   2.1e-15   1.7e-12       2      88 ..     412     508 ..     412     536 .. 0.82

  Alignments for each domain:
  == domain 1  score: 47.8 bits;  conditional E-value: 2.1e-15
  KAsynt_C_assoc   2 npeipaleegrlkVvteptpwpggivgvNsfGfGGsnvHviLksnk...........kekrkeesk.......eeslprLlvlsgrteeaveall 78 
                     n  ip l++++l+++ +  + + ++++vN+fG+GG+n+HviL+s +           +               +  + r++vls++te++ +  +
      EEA19308.1 412 NTTIP-LKQLKLRIPLQLERRDLRRISVNCFGYGGTNAHVILDSVDsffappsplagR-------ItassksqKLVRNRIFVLSAETEKSAQGSA 498
                     7889*.****************************************787777666552.......0333333356899****************9 PP

  KAsynt_C_assoc  79 ekleehllda 88 
                     +++ e+l+++
      EEA19308.1 499 QRMVEYLKTK 508
                     9999996554 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.9   0.0   3.1e-13   2.5e-10       1      97 []    1428    1532 ..    1428    1532 .. 0.86

  Alignments for each domain:
  == domain 1  score: 40.9 bits;  conditional E-value: 3.1e-13
                       EEEET-TTSHHHHHHHCTS...T...SSEEEEEESSHHHHHHHHHHHHHTTTTEEEEESBCCGBS....SSTTTEEEEEEESTGGGSSHHHH CS
  Methyltransf_25    1 vLdlGcGtGrltlalakrl...g...kakvtgvDiseemleaareraeeeglnvefvqgdaedlp....fedgsfDlvvssgalhhlsdedl 82  
                       vL++G+Gt  +tl l++rl       ++++  +Dis+++  aa+er+ + +  v++++ +ae+ p    f  +s+D++++++++h +s  ++
       EEA19308.1 1428 VLEIGAGTASVTLPLLQRLkpdDrvlASRYDFTDISAGFFPAAKERLVDFEDIVNYQVLNAENDPveqgFTPNSYDIIIACNVIHATS--RI 1517
                       9*****************97541466788899***************98656788888888776655668999*******88899876..89 PP

                       HHHHHHHHHHEEEEE CS
  Methyltransf_25   83 ekalkeiarvLkpgG 97  
                       e++l++++++LkpgG
       EEA19308.1 1518 ETVLNNVRSLLKPGG 1532
                       9*************9 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.6   0.0   4.3e-12   3.5e-09       4     154 ..    2169    2320 ..    2166    2344 .. 0.77

  Alignments for each domain:
  == domain 1  score: 36.6 bits;  conditional E-value: 4.3e-12
                    TSHHHHHHHHHHHTT-EEEEEESSGGH....HHHHHHHHHHTTSEE..EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-H CS
  adh_short_C2    4 sgIGraiAkalaeeGaevvltdlneea....kkrveelaeelgaev..lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsr 92  
                     g+G+ i+  +ae+Ga+ ++t  +       + ++ e a++lg+ v   +cDV de+q++++v+e+++++  + ++v +a i ++  + f e++ 
    EEA19308.1 2169 GGLGKRIVLWMAERGAKNIVTFSRSGTmneqALSLMESAKKLGTIVhvKKCDVGDENQLKQVVAELKDNLPPIRGIVQSAMILED--SVFDEMTY 2261
                    599*************966654443333211234456666677553449***********************************9..9******* PP

                    HHHHHHHHHHTHHHHHHHHHHHHHCTSCCEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHH CS
  adh_short_C2   93 eefdraldvnlyslfllakaalplmkeggsivnlssvgaervvpnynaygaaKaalealtry 154 
                    +++  a++ +++++++l +a+   +      v lss  a  +  +++ y+aa a   al++y
    EEA19308.1 2262 QQWSGAVNPKVKGTWNLHNALPSSL---DFFVMLSSAVALGGNVGQSNYSAACAFQDALAHY 2320
                    ****************988765444...4688888888888888888888887777777766 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.0   0.0     9e-11   7.3e-08       1      96 []    1429    1536 ..    1429    1536 .. 0.87
   2 ?   -1.7   0.0       5.8   4.7e+03       9      41 ..    2174    2207 ..    2168    2229 .. 0.73

  Alignments for each domain:
  == domain 1  score: 33.0 bits;  conditional E-value: 9e-11
                       EEET-TTSHHHHHHH......HTT...SEEEEEES-HHHHHHHHHHCCHHT-EEEETTEECCC....TSS-TT-EEEEEEES-CCC-CCHHH CS
  Methyltransf_11    1 LdvGcGtGrlaeala......krg...arvvgvDlskemlklakekaseeglkvefvvadaek....lpfednsfDlvvssevlhhvedpek 79  
                       L++G+Gt +++ +l       +     +r+  +D+s+ +  +ake+ ++ +  v+++v +ae+      f  ns+D++++ +v+h   + e 
       EEA19308.1 1429 LEIGAGTASVTLPLLqrlkpdD-RvlaSRYDFTDISAGFFPAAKERLVDFEDIVNYQVLNAENdpveQGFTPNSYDIIIACNVIHATSRIET 1519
                       89*************6555543.158899999***************9988878899999997443246999******************** PP

                       HHHHHHHHEEEEEEEEE CS
  Methyltransf_11   80 alkeiaRvLkpgGllvi 96  
                       +l++++ +LkpgG++++
       EEA19308.1 1520 VLNNVRSLLKPGGKFIL 1536
                       **************985 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 5.8
                       HHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHH CS
  Methyltransf_11    9 rlaealakrg.arvvgvDlskemlklakekasee 41  
                       r++ ++a+rg +++v++  s +m ++a +  + +
       EEA19308.1 2174 RIVLWMAERGaKNIVTFSRSGTMNEQALSLMESA 2207
                       67789999999************99885544444 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.8   0.0   3.8e-11   3.1e-08       3      65 ..    2451    2513 ..    2449    2515 .. 0.92

  Alignments for each domain:
  == domain 1  score: 33.8 bits;  conditional E-value: 3.8e-11
  PP-binding    3 lrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaa 65  
                  ++  +++v+ +p+e+++pd++l+ +G+DSl+avel +++ + ++  +pl +l    +++ela+
  EEA19308.1 2451 ILVQLSKVTALPVERLNPDESLDAYGVDSLVAVELRNWIGAYLQANVPLLVLRGTGSIQELAE 2513
                  55568999********************************************77******997 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.0   0.0   1.2e-10     1e-07       8     161 ..    1404    1585 ..    1398    1610 .. 0.62

  Alignments for each domain:
  == domain 1  score: 32.0 bits;  conditional E-value: 1.2e-10
  Methyltransf_23    8 elsdklerllpk......lraggrvLdiGcGtG.illevlre.....ngf..svtgvDlspeaveiae............kakkaqkdqfde 73  
                       ++ + +++++++      + ++++vL+iG+Gt   +l++l++     ++    +++ D+s    + a+            +  +       +
       EEA19308.1 1404 RCIRCYDQIAAYcaqygrQTPDMKVLEIGAGTAsVTLPLLQRlkpddRVLasRYDFTDISAGFFPAAKerlvdfedivnyQVLN-------A 1488
                       55555555553333334478888**********445666644344442224578888888654444445555765443332222.......2 PP

  Methyltransf_23   74 qeaaepqg....kfdlIvlrevlehvpdppellrqiatllkpgGylllseplasl...........kedrllldwlylvpag.rhisffsar 149 
                       ++++++qg    ++d+I++ +v++     + +l+++++llkpgG ++l+e++ ++                   w+   ++g + + +    
       EEA19308.1 1489 ENDPVEQGftpnSYDIIIACNVIHATSRIETVLNNVRSLLKPGGKFILMEITMNQlyynlfygtfsG-------WWSGYDEGrTMSPLLEIP 1573
                       333333335555**************************************98777554444433330.......444444442333555555 PP

  Methyltransf_23  150 slkelleeaGle 161 
                       +++e l++ G+e
       EEA19308.1 1574 QWEEKLRKTGFE 1585
                       555555555555 PP

>> Ubie_methyltran  ubiE/COQ5 methyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       2.7   2.2e+03      87     129 ..     489     531 ..     482     537 .. 0.82
   2 !   26.6   0.0     4e-09   3.3e-06      47     157 ..    1424    1542 ..    1410    1558 .. 0.79
   3 ?    1.4   0.0      0.21   1.7e+02      34      77 ..    2403    2446 ..    2398    2459 .. 0.83

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 2.7
                      HHHHHHHHHTSSTEEEEE--TTT-TTS-T-EEEEEEES-GGG- CS
  Ubie_methyltran  87 vgekklkeegkinieflqanaeeLpfeddsfDvvtvsfGlrnv 129
                      ++ek ++ +++  +e+l+++a e  ++++  D ++ + G r v
       EEA19308.1 489 ETEKSAQGSAQRMVEYLKTKASEYAESEGWLDNLAYTLGRRSV 531
                      4566677777889***************999998888887765 PP

  == domain 2  score: 26.6 bits;  conditional E-value: 4e-09
                       -TTEEEEES-TT-HHHHHHHHHHHHHH.....EEEEEES-HHHHHHHHHHHHHHTSSTEEEEE--TTT-T....TS-T-EEEEEEES-GGG- CS
  Ubie_methyltran   47 rgakvlDvagGtgDlafklsdsvgekg.....kvvvlDinenmLkvgekklkeegkinieflqanaeeLp....feddsfDvvtvsfGlrnv 129 
                       +  kvl++ +Gt+ +++ l++ ++        + +  Di++  +  ++++l +   i +++ + nae+ p    f+ +s+D++     +  +
       EEA19308.1 1424 PDMKVLEIGAGTASVTLPLLQRLKPDDrvlasRYDFTDISAGFFPAAKERLVDFEDI-VNYQVLNAENDPveqgFTPNSYDIIIACNVIHAT 1514
                       4569*******************99986677777899*************9886554.44444455444411226679************** PP

                       S-HHHHHHHHHHHEEEEEEEEEEEE--- CS
  Ubie_methyltran  130 tDklkaLkeayrvlkpGGrlvvlefskv 157 
                       + ++++L++++  lkpGG+++ +e++  
       EEA19308.1 1515 SRIETVLNNVRSLLKPGGKFILMEITMN 1542
                       ***********************98654 PP

  == domain 3  score: 1.4 bits;  conditional E-value: 0.21
                       HHHHHHHHH--S--TTEEEEES-TT-HHHHHHHHHHHHHHEEEE CS
  Ubie_methyltran   34 lWkkfveklvavkrgakvlDvagGtgDlafklsdsvgekgkvvv 77  
                       +W + ++ ++  ++ga+ + vag t+D+ ++l ++  ++  v+v
       EEA19308.1 2403 VWMEDMKFVHVRRQGASQVQVAGATSDVIAELRSASTSEDAVEV 2446
                       6888888888999******************9887776665544 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.0     3e-08   2.5e-05       3     117 ..    1424    1543 ..    1422    1582 .. 0.79

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 3e-08
  Methyltransf_31    3 kglrvlDlGCGtGeltfelaeelgpkae.....vvGiDiseeaielArenaqklgld.nveFeqgdieelekl.ledekfDlilsnevlnal 87  
                        +++vl++G+Gt   t+ l ++l p+ +     +   Dis+     A+e++ + +   n+++  ++    e + ++++++D+i++ +v++a+
       EEA19308.1 1424 PDMKVLEIGAGTASVTLPLLQRLKPDDRvlasrYDFTDISAGFFPAAKERLVDFEDIvNYQVLNAENDPVE-QgFTPNSYDIIIACNVIHAT 1514
                       6899*****************99997773333344568888888888887664443335555555555555.55888*************** PP

  Methyltransf_31   88 adpdkileeiervlkpggilliedprllae 117 
                       +  + +l+++ ++lkpgg +++ ++  + +
       EEA19308.1 1515 SRIETVLNNVRSLLKPGGKFILMEIT-MNQ 1543
                       *********************99988.444 PP

>> Methyltransf_16  Lysine methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   1.8e-06    0.0015      43     155 ..    1421    1537 ..    1395    1548 .. 0.77
   2 ?   -1.3   0.0       1.9   1.5e+03      16      41 ..    1958    1983 ..    1946    1994 .. 0.72

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 1.8e-06
  Methyltransf_16   43 nelsklsvlELGsGtGlvGlavaell.peakviltDleellellkknielnkn...alkskvkvevLdWgeeleedllekeevDlilaaDcv 130 
                       +++ +++vlE+G+Gt  v l + + l p+ +v+   + + +++      ++k+     ++ v+++vL+ +++  e+ ++++++D+i+a  ++
       EEA19308.1 1421 RQTPDMKVLEIGAGTASVTLPLLQRLkPDDRVLA-SRYDFTDISAGFFPAAKErlvDFEDIVNYQVLNAENDPVEQGFTPNSYDIIIACNVI 1511
                       5667899*************99888646666654.3333444444444333333335899************99****************** PP

  Methyltransf_16  131 YledslelLvkvLkellkkesk.vlv 155 
                          + +e+ ++ ++ llk+ +k +l+
       EEA19308.1 1512 HATSRIETVLNNVRSLLKPGGKfILM 1537
                       ******************99996666 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.9
  Methyltransf_16   16 sigrkvWdaavvlvkylekklakelg 41  
                       s ++ v +aa++l+kyl  +++ ++g
       EEA19308.1 1958 SGAGAVGQAAIMLAKYLGAEIFVTVG 1983
                       55777888888888888877766544 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   3.5e-06    0.0029       1     126 [.    2163    2304 ..    2163    2312 .. 0.70

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 3.5e-06
   3Beta_HSD    1 vvtGgaGFlGralvkeLvrleelkevrvlD.....lrespelleelskvnvkk.viegDvtdkdkleealegvdvvi.......hlaslv..dvag. 81  
                  +v+Gg G lG+++v  + +++  k++  +       ++  +l e+++k++++  v ++Dv d+++l++++ + + ++         a +    v+  
  EEA19308.1 2163 IVVGGLGGLGKRIVLWMAERGA-KNIVTFSrsgtmNEQALSLMESAKKLGTIVhVKKCDVGDENQLKQVVAELKDNLppirgivQSAMILedSVFDe 2258
                  69***************99995.888777767764445557889999999987799*************9998754421111002222211123332 PP

   3Beta_HSD   82 kltedeimkvn..vkGTrnvleacvkagvrvlvYtSsaevvgpnslg 126 
                  +++++    vn  vkGT n+   ++ +++ ++v  Ssa + g+n+ +
  EEA19308.1 2259 MTYQQWSGAVNpkVKGTWNL-HNALPSSLDFFVMLSSAVALGGNVGQ 2304
                  333333344554499**995.66789999********9999998765 PP

>> Thiolase_N  Thiolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   0.00013      0.11      76     116 ..     196     235 ..     186     256 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00013
                 SEEEEEEHGGGHHHHHHHHHHHHHHTTSHSEEEEEEEEEST CS
  Thiolase_N  76 vpavtvnkvcsSglkavalaaqsiaageadvvvagGvEsms 116
                  p+ tv+  cs ++ a++ a+qs+++ge d   + Gv  ++
  EEA19308.1 196 GPSFTVDTGCSASMVALHSAVQSLRTGETDRSFVAGVN-LT 235
                 5889**************************99999984.44 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0       1.5   1.2e+03     124     146 ..    1145    1167 ..    1144    1175 .. 0.86
   2 ?   10.0   0.1   0.00048      0.39      20      58 ..    1945    1982 ..    1939    2000 .. 0.76

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 1.5
                   EEETTGGGT-SBTT--TBBTTSE CS
  AlaDh_PNT_C  124 ivDvAidqGGnvetsrltthgep 146 
                   ++Dv + qG  ++t++++ ++ +
   EEA19308.1 1145 VIDVKTTQGSAIATVKPSDEDAS 1167
                   89***************988765 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00048
                   TCEETCB---EEEEE.STSHHHHHHHHHHHHTT-EEEEEE CS
  AlaDh_PNT_C   20 aGgvpgvepakvlvi.GgGvaGlqAiatakglgakVtvlD 58  
                   +G+++  +  +vl+  G+G +G++Ai  ak lga++ v+ 
   EEA19308.1 1945 MGKLK--KGERVLIHsGAGAVGQAAIMLAKYLGAEIFVTV 1982
                   66666..555666635*******************99864 PP

>> DREV  DREV methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00025       0.2      91     187 ..    1421    1537 ..    1409    1555 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00025
        DREV   91 sdqedkklldlGaGdGeitkrvaptfee................vyatelsetmrdrlkkkkynvlsale.lqetdv...kldlilclnlldrcfdp 167 
                   +  d k+l++GaG   +t  + + ++                  +   + e++ d  +  +y+vl a +   e ++    +d+i + n++      
  EEA19308.1 1421 RQTPDMKVLEIGAGTASVTLPLLQRLKPddrvlasrydftdisaGFFPAAKERLVDFEDIVNYQVLNAENdPVEQGFtpnSYDIIIACNVIHATSRI 1517
                  4556889************999888877788888888888866545556677788888899*****865435555543338**************** PP

        DREV  168 lklledirsalepngrviva 187 
                   ++l+++rs l+p g+ i+ 
  EEA19308.1 1518 ETVLNNVRSLLKPGGKFILM 1537
                  ***************99985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2534 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       497  (0.0277205); expected 358.6 (0.02)
Passed bias filter:                      482  (0.0268838); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                        22  (0.00122706); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              22  [number of targets reported over threshold]
# CPU time: 1.25u 0.31s 00:00:01.56 Elapsed: 00:00:00.50
# Mc/sec: 15225.85
//
Query:       EEA19309.1  [L=565]
Description: AMP dependent CoA ligase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.3e-64  217.0   0.0    4.4e-64  216.6   0.0    1.1  1  AMP-binding    AMP-binding enzyme
    2.7e-17   63.5   0.3    6.1e-17   62.4   0.3    1.7  1  AMP-binding_C  AMP-binding enzyme C-terminal domain


Domain annotation for each model (and alignments):
>> AMP-binding  AMP-binding enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  216.6   0.0   4.9e-68   4.4e-64      19     422 ..      48     461 ..      33     462 .. 0.81

  Alignments for each domain:
  == domain 1  score: 216.6 bits;  conditional E-value: 4.9e-68
                  STEEEEHHHHHHHHHHHHHHHH.HTTSSTT-E......EEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEEEETCTCCCHHH CS
  AMP-binding  19 egqtlTYreldervnrlAagLr.slGvkkgdr......VaillpnspewvvallailkaGavvvplnptltaeelayiledseakvliatvdsellek 109
                  +g+++T + l+e+v+ +A+ L  +lG k+ +        ai++ ns+e++++  a+ ++++++ ++ ++++++e+++ l+ s++k+++  v+  ll+ 
   EEA19309.1  48 TGKQYTLNALREQVDLVAQSLSnELGWKPNEGeswdkvLAIYSFNSVEYLILCWAVHRLNGICLTIHTGSSNKEIEQHLTRSKCKAIF--VSPSLLKT 143
                  6799***********************997644455559*************************************************..77777666 PP

                  HHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS...........-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHH.HHH CS
  AMP-binding 110 lleaaakleavklvivldadellkeeelkeeeeseekae...........kpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslk.let 195
                   l+++  l+ +++ i++   + +  +++++++  + ++              + e+ + ++++ay+  TSGT G  K + + h n++an+ + + ++ 
   EEA19309.1 144 CLQVTNPLDIPQKNIYTIPVPGEPVSTVDGHK--SFEQLlaagpdlpslePLKWERGQGKKQVAYLAATSGTSGLQKLAKIGHYNIIANILQTAtFD- 238
                  66666666666655544422222222333333..33331445667777763334555678******************************9976433. PP

                  CSCCTT..T-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEEEE CS
  AMP-binding 196 rfklke..ddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvllg 291
                    + ++   +  + +lpl+h ++l     + l +G +++l p+++ ++   +l++++++k   +++vP+++ al+++++l  ++   dlss++++++g
   EEA19309.1 239 -GGYTPsqPESGILFLPLSHTYAL-EVSHMLLWRGDAIILQPNFDMMK---MLKAVTTFKLERLYLVPAIVGALIKNPFLF-QMF--DLSSVKTIISG 328
                  .2233342344599*********8.77777777788888877776644...68***********************87776.233..*********** PP

                  SS-EBHHHHHHHHHHHTC.EEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBEETTSEEEEEEEETTS-SEBTT-HHHHHHH CS
  AMP-binding 292 geplspellrffralfge.evlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeetgepvpdgeeGellvrgpgvmkgYlkkpeataea 388
                   +p  ++l ++++++ ++ ++l gYGlTE ++++t +++ +d ++ gs G  lp+v+++++De++    +++++Ge+l++gp++ +gYl++peata  
   EEA19309.1 329 SAPFDKNLGEAVKKVRPDwKILPGYGLTESSIIAT-FTNAHD-QMYGSSGSLLPEVQLRLIDENGIDIEEHEKPGEVLLKGPNIISGYLNDPEATATL 424
                  ***************999****************9.664444.799*****************96666667777************************ PP

                  EEETCCEEEEEEEEEEE....TTSEEEEEEECCCEEEE CS
  AMP-binding 389 fdsegrwlrTGDlgrld....edGyleivgRkkdlikl 422
                  +dse +wl++GD+g ++    ++ +l iv+R+ d+ik+
   EEA19309.1 425 IDSE-GWLHSGDVGLIRlspqQNEHLVIVDRLRDMIKV 461
                  *955.7*********7557655789************8 PP

>> AMP-binding_C  AMP-binding enzyme C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.4   0.3   6.8e-21   6.1e-17       2      76 .]     471     552 ..     470     552 .. 0.88

  Alignments for each domain:
  == domain 1  score: 62.4 bits;  conditional E-value: 6.8e-21
                    HHHHHHSSTTEEEEEEE-----TTS---EEEEEE---..---.....HHHHHHHHHHHHT-TT.TS-SEEEE-S---B-TTS- CS
  AMP-binding_C   2 vEsalvshpaVaeaaVvGvpdevkGealvafVvlkdg..sea.....leeeLkahvrkelgpy.avpkkvvfvdelpktrsGK 76 
                    +E+al+ hpaV+++aV+Gv+de  Ge+++afVv +++  + +     ++e +++hv+k+l ++ +  +++ f++e+pk+++ K
     EEA19309.1 471 IEAALIVHPAVRDVAVIGVKDEHAGERAKAFVVRSPDtmQ-DlseeqVKESIREHVEKHLSELhWLHDRISFIAEIPKNQNNK 552
                    9********************************8655342.224457***************845999************988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (565 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       464  (0.0258799); expected 358.6 (0.02)
Passed bias filter:                      447  (0.0249317); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.68u 0.32s 00:00:01.00 Elapsed: 00:00:00.51
# Mc/sec: 3322.88
//
Query:       EEA19310.1  [L=259]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.3e-18   65.5   0.0    9.4e-18   65.2   0.0    1.4  1  Thioesterase   Thioesterase domain
    0.00037   21.2   0.0     0.0005   20.7   0.0    1.3  1  Abhydrolase_6  Alpha/beta hydrolase family
    0.00064   19.0   0.1       0.41    9.9   0.0    2.3  2  Hydrolase_4    Serine aminopeptidase, S33
     0.0057   16.5   0.0     0.0075   16.1   0.0    1.1  1  Abhydrolase_3  alpha/beta hydrolase fold
  ------ inclusion threshold ------
      0.013   15.3   0.0      0.018   14.9   0.0    1.3  1  Abhydrolase_2  Phospholipase/Carboxylesterase
      0.047   13.1   0.0       0.07   12.6   0.0    1.2  1  Cellulase      Cellulase (glycosyl hydrolase family 5)
      0.048   12.7   0.0      0.088   11.9   0.0    1.4  1  HpaB           4-hydroxyphenylacetate 3-hydroxylase C termina
       0.15   11.9   0.1       0.32   10.9   0.0    1.5  2  CBP4           CBP4
       0.17   11.5   0.0       0.35   10.5   0.1    1.7  2  Abhydrolase_1  alpha/beta hydrolase fold
       0.18   11.3   0.0        0.3   10.6   0.0    1.3  1  DUF2974        Protein of unknown function (DUF2974)


Domain annotation for each model (and alignments):
>> Thioesterase  Thioesterase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.2   0.0   5.3e-21   9.4e-18       2     120 ..      20     136 ..      19     242 .. 0.89

  Alignments for each domain:
  == domain 1  score: 65.2 bits;  conditional E-value: 5.3e-21
                   EEEEE--TTCCSGGGHHHHHHCTTCEEEEEEECSTTSTSHHHCTTCHHHHHHHHHHHHHHH-SSSSEEEEEETHHHHHHHHHHHHHHHC.T-SEEEE CS
  Thioesterase   2 pLflfppagGsasvfrslasklsdpvvevlavqlpgrerdepplesieelaaeyaealrqiqpegPyalfGhSlGgllAfevArqLesq.Glavksl 97 
                   pLfl +++gG +++++s+    +d    +++++ p+++++++  ++i e+a+ey+e++++i p     l+G+SlGgl+A e+++ L +     v +l
    EEA19310.1  20 PLFLIHDGGGTITSYHSFGDLGRD----LYGIYNPRFQDNKKWTSGIVEMAQEYVEMIKSISPANRIMLGGWSLGGLIALEMSHILANDlIVNVVGL 112
                   8*****************998888....8************************************************************999***** PP

                   EEESC.CCCCCHHCHHCCCHTTHH CS
  Thioesterase  98 flids.sapseteaqeasrraede 120
                   ++id  ++p +  a+ +++  +++
    EEA19310.1 113 IMIDIvYPPAISAANLNPDVRDMN 136
                   ****72555665555555555554 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.7   0.0   2.8e-07    0.0005      51     144 ..      67     191 ..      21     240 .. 0.56

  Alignments for each domain:
  == domain 1  score: 20.7 bits;  conditional E-value: 2.8e-07
                    HHHHHHHCCTT..TTSEEEEEETCHHHHHHHHHHCC........EE.EEES-............----TTT..............S----TTHHHH CS
  Abhydrolase_6  51 adlaalldelaagggpvvlvGHSlGGalalaaapla......lvvg.vlldp..pp........talpagl..............laaalelllal 115
                    +++++++ ++   ++++ l G+SlGG++al+  + +       vvg +++d   pp        +     +              +++ ++l++ +
     EEA19310.1  67 QEYVEMIKSIS-PANRIMLGGWSLGGLIALEMSHILandlivNVVGlIMIDIvyPPaisaanlnP-----DvrdmnlsrdipvkqRQRMMKLIKEA 156
                    55555555553.455569*************5555578889855667888886544444433331.....02233333333334455555555544 PP

                    HHTT-C...CCCHCCH.....S-HSCCCCHHHCCCCH CS
  Abhydrolase_6 116 lallrl...lawlsre.....plprlfladedadaaw 144
                    +a++ +   ++w s+      +++ ++ ++++  +  
     EEA19310.1 157 TASAKAyqlPTWTSGSesdssMDSISMPSPPP--TVL 191
                    44333334467765444455322224444444..222 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.9   0.0   0.00023      0.41      59      94 ..      63      98 ..      56     115 .. 0.84
   2 !    6.9   0.0    0.0019       3.4     161     203 ..     134     176 ..     125     182 .. 0.89

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00023
  Hydrolase_4 59 vdDlaafvekvkeehpelplfllGhSmGGliallyl 94
                 v+ ++++ve++k+ +p  +++l G S+GGlial++ 
   EEA19310.1 63 VEMAQEYVEMIKSISPANRIMLGGWSLGGLIALEMS 98
                 55678999************************9876 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0019
  Hydrolase_4 161 dplvhgkitvrlllelldamkrleeraakitlPllllhGeaDk 203
                  d  ++++i v+  + +++++k+++++a++++lP++   +e+D 
   EEA19310.1 134 DMNLSRDIPVKQRQRMMKLIKEATASAKAYQLPTWTSGSESDS 176
                  666789999999************************9999996 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0   4.2e-06    0.0075      69     146 ..      78     158 ..      56     204 .. 0.68

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 4.2e-06
                    TTCEEEEEEETHHHHHHHHHHHHHHHTT---EEEEEEE...SE..-SSTSSTTSHHHHHCHHTTTSSSSCHHHHHHHHHHHSS CS
  Abhydrolase_3  69 dpsrivlaGdSaGGnlaaavalrardegepkvagqvli...yP..vtdlertesesikkaeeladgplltraaldlfwrlylp 146
                     ++ri+l+G S GG +a+ +++ ++++  ++v+g+++i   yP     + ++ +++ ++ +  +d p+ +r+++  +++  ++
     EEA19310.1  78 PANRIMLGGWSLGGLIALEMSHILANDLIVNVVGLIMIdivYPpaI-SA-ANLNPDVRDMNLSRDIPVKQRQRMMKLIKEATA 158
                    467******************9999886777777776433377642.33.444566655555588888777777777766553 PP

>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   0.0   9.8e-06     0.018      83     129 ..      59     104 ..      43     181 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 9.8e-06
                    HHHHHHHHHHHHHHHHHTT--GGGEEEEEETHHHHHHHHHHHT-SS- CS
  Abhydrolase_2  83 ikksaekleelidaelkkgipssriiigGFSqGaalalylaltlpkk 129
                    ++ ++e+ +e ++  +k   p++ri++gG S G+ +al+ + +l + 
     EEA19310.1  59 TSGIVEMAQEYVE-MIKSISPANRIMLGGWSLGGLIALEMSHILAND 104
                    4444444444443.3455579*****************998877663 PP

>> Cellulase  Cellulase (glycosyl hydrolase family 5)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   3.9e-05      0.07     129     176 ..      49      88 ..      42     129 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 3.9e-05
                 SS--STTCTCCTCHHHTTHHHHHHHHHHHHHHHHTTSSEEEEECHHHH CS
   Cellulase 129 NEPhgnntgaewtseeadevkayaeeaikaIRavgpnrliivegnsws 176
                 N P+ +++ ++w    +  + ++a+e +++I+++ p + i+++g  ws
  EEA19310.1  49 N-PRFQDN-KKW----TSGIVEMAQEYVEMIKSISPANRIMLGG--WS 88 
                 5.555455.689....99999***********************..76 PP

>> HpaB  4-hydroxyphenylacetate 3-hydroxylase C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   4.9e-05     0.088     128     163 ..     128     162 ..     102     170 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 4.9e-05
                 THHHHHHHT-BTT.B-HHHHHHHHHHHHHHHTSHHH CS
        HpaB 128 igpllekylrgsegvsaeeRvkllklawdltgsefg 163
                 + p+++ +  +  ++++++R +++kl++++t+s+ +
  EEA19310.1 128 LNPDVRDMNLS-RDIPVKQRQRMMKLIKEATASAKA 162
                 55566555445.55*******************865 PP

>> CBP4  CBP4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0         4   7.2e+03      59      70 ..      67      78 ..      64      82 .. 0.59
   2 ?   10.9   0.0   0.00018      0.32      37      81 ..     126     173 ..     107     185 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 4
        CBP4 59 qelvkivketsk 70
                qe+v+++k  s 
  EEA19310.1 67 QEYVEMIKSISP 78
                566666665554 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00018
        CBP4  37 krlsPelrkkyeknrelRqkeqqelvkivketsksdd....piWktgpi 81 
                 ++l+P++r     +r++  k+ q+++k +ke ++s +    p W  g++
  EEA19310.1 126 ANLNPDVRDMN-LSRDIPVKQRQRMMKLIKEATASAKayqlPTWTSGSE 173
                 579****9765.589********************9999999**99987 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.1    0.0002      0.35      55      93 ..      62     100 ..      17     184 .. 0.83
   2 ?   -3.4   0.0       3.3     6e+03     137     160 ..     199     222 ..     193     234 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.0002
                    SHHHHHHHHHHHHHHCTTSSEEEEEETHHHHHHHHHHHH CS
  Abhydrolase_1  55 gtasvaddldrildalgddkltlvGhSmGGmialayaae 93 
                       + ++++++i+   +  ++ l G+S+GG+ial++   
     EEA19310.1  62 IVEMAQEYVEMIKSISPANRIMLGGWSLGGLIALEMSHI 100
                    5566789999************************98765 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 3.3
                    HHHHHHHHHCCSCHHHHHHHHHHH CS
  Abhydrolase_1 137 rnpagplladelaaleqrhrlvda 160
                    + + g+++ ++l++  ++ +lv++
     EEA19310.1 199 PSRRGTKIPNMLGWDSYEADLVKE 222
                    667788888999999998888866 PP

>> DUF2974  Protein of unknown function (DUF2974)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00017       0.3      69     103 ..      64      99 ..      57     117 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00017
     DUF2974  69 esAlkYlnkileesegk.iylgGhSkGGnlAvyaam 103
                 e A +Y+++i + s+ + i+lgG+S GG +A+  + 
  EEA19310.1  64 EMAQEYVEMIKSISPANrIMLGGWSLGGLIALEMSH 99 
                 5799******99999877**********99986555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (259 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       518  (0.0288917); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.40
# Mc/sec: 1939.22
//
Query:       EEA19311.1  [L=3936]
Description: nonribosomal peptide synthetase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   2.8e-219  727.9   0.0    2.8e-75  253.5   0.0    3.2  3  AMP-binding    AMP-binding enzyme
     1e-154  515.6   0.0    6.7e-41  140.4   0.0    4.4  4  Condensation   Condensation domain
    1.6e-52  175.8  11.0    3.6e-11   43.3   0.0    5.9  5  PP-binding     Phosphopantetheine attachment site
    1.3e-06   29.3   0.0        1.3   10.1   0.0    4.0  3  AMP-binding_C  AMP-binding enzyme C-terminal domain
  ------ inclusion threshold ------
      0.085   11.4   0.4        5.1    5.5   0.0    3.3  4  AATase         Alcohol acetyltransferase


Domain annotation for each model (and alignments):
>> AMP-binding  AMP-binding enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  253.5   0.0   7.8e-79   2.8e-75       2     423 .]     601     999 ..     600     999 .. 0.88
   2 !  224.8   0.1   4.2e-70   1.5e-66       4     423 .]    1688    2082 ..    1685    2082 .. 0.87
   3 !  246.2   0.0   1.3e-76   4.8e-73       4     423 .]    2775    3168 ..    2772    3168 .. 0.89

  Alignments for each domain:
  == domain 1  score: 253.5 bits;  conditional E-value: 7.8e-79
                  HHHHHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEEE CS
  AMP-binding   2 eeqaaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakvli 99 
                  +++a ++p++ a+ +   +  lTY+el+++++ l+++L s Gv+++  V++++++s   v+a+lail+aG++vvpl  + +  ++  il dsea +++
   EEA19311.1 601 DQKAHEQPNAQAIDS--WDGNLTYEELNQQAKILSSHLISQGVRPEVMVGMCMEKSKWAVIAMLAILYAGGAVVPLGVQHPLSRITDILIDSEAVLIL 696
                  678999*******55..6779******************99********************************************************* PP

                  ETCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHHHHCS CS
  AMP-binding 100 atvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkletrf 197
                    vds+++ +l+e+ +      ++iv+d++ +++     ++  +e         +++ p + a +iYTSG+TGkPKGV l+h++l++++ ++     f
   EEA19311.1 697 --VDSQQARRLAEVSK------AKIVVDEALFNTI---IITPMTEP------NIPNTIPVNAAWVIYTSGSTGKPKGVLLEHGALCSSMIAH--GAVF 775
                  ..99988666666554......6899997665544...33332222......233456899*****************************97..4458 PP

                  CCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEEEESS-E CS
  AMP-binding 198 klkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvllggepl 295
                  +++++ +v++++ + +++++  e +++ll G++++++++d+++  ++l+++i + ++ ++ ++ + +  +l +          +l+++++++l gep+
   EEA19311.1 776 DMGRHARVFQFAAYTFDAAI-QENFATLLYGGCICIPSEDDRM--NHLARAIIDRNADYVGLTSSTATLILPH----------ELPHVKQLILFGEPV 860
                  8999***************7.***************9999884..578999999****************998..........899************ PP

                  BHHHHHHHHHHHTCEEEEEEEEGGGSSECEE.CHCTTTCTSTTS-BEE-TTEEEEEE-TTT.SCBEETTSEEEEEEEETTS-SEBTT-HHHHHHHEEE CS
  AMP-binding 296 spellrffralfgeevlegYGlTEttgvvtv.lpleedkkklgsvGkplpgvevkivDeet.gepvpdgeeGellvrgpgvmkgYlkkpeataeafds 391
                   +++++++  +   ++l+gYG+TE++++ +v  p ++ +++++ +G++  g+   +vD ++ ++++p g +Gell+ gp +++gY ++p +t+ af++
   EEA19311.1 861 KASVVEAWLGHA--RILNGYGPTECSIFSSVsKPFKDVRSQISNIGFVTTGN-FWVVDSSDlNRLCPIGCPGELLIEGPLLARGYVNDPVKTNNAFIT 955
                  *****9999996..59*************777555666678999****9995.5555555515667*******************************8 PP

                  ...........TCC.EEEEEEEEEEETTSEEEEEEECCCEEEET CS
  AMP-binding 392 ...........egr.wlrTGDlgrldedGyleivgRkkdliklr 423
                             +gr ++rTGD++  + dG+l ++gR + ++k+r
   EEA19311.1 956 dpcfirqlklgSGRrMYRTGDIVQQNSDGSLTYLGRRDTQVKIR 999
                  89******9964556***************************96 PP

  == domain 2  score: 224.8 bits;  conditional E-value: 4.2e-70
                   HHHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEEE CS
  AMP-binding    4 qaaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakvli 99  
                   + +++p+++a+     +  +TY+eld++++r++++L ++Gv ++  V++++++s    va+lail+aG+ v+pl  + + e++a il+ds ++v++
   EEA19311.1 1688 SIQQRPNDIAIDA--WDGAFTYEELDRHAKRVSSYLINIGVVPDMLVGMCMDKSKWASVAVLAILYAGGGVMPLGVQHPLERVATILSDSSCTVIL 1781
                   67899******55..7789******************99********************************************************* PP

                   ETCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHHHH CS
  AMP-binding  100 atvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslklet 195 
                     +d++++e+l+          ++ +++ ++l k+++ ++++     +   +++  ++p++   +iYTSG+TG+PKGV+l h++l++ ++ +  + 
   EEA19311.1 1782 --CDKQQNERLQG--------MTTHIVEVKGLVKSSTGPITQ-----S--LCTT--VRPEHAGWVIYTSGSTGNPKGVILQHKALCSGIKGH--SA 1856
                   ..88777444422........345566766777776666555.....1..4455..89******************************9997..45 PP

                   CSCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEEEE CS
  AMP-binding  196 rfklkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvllg 291 
                   rfk++ + + +++    +++ +  e++ +l++G+ v+++++ +++  + l ++i++ +v+++ ++ + +  + +   ++      d + ++++ l 
   EEA19311.1 1857 RFKFDTNTRQFQFGAHTFDITI-QEICSTLIHGGVVCVPSEHQRM--NKLSATIAAMQVNFLGLTSTSASLI-D---PR------DTPTVKTLTLF 1939
                   6888889999***********7.***********88887766663..45789********998888888877.3...34......7889***999* PP

                   SS-EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBEETTSEEEEEEEETTS-SEBTT-HHHHHH CS
  AMP-binding  292 geplspellrffralfgeevlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeetgepvpdgeeGellvrgpgvmkgYlkkpeatae 387 
                   ge++ p++++ +      ev+++YG++E+t++ ++ p  +dkk    +G pl g+ + +   +  +++p g +Gell+ gpg+++ Yl++  +t+ 
   EEA19311.1 1940 GEAVKPSVVETWLPYA--EVINVYGPSECTIHSVCSPAIKDKKDSLNIGYPLNGAAWVVEPTNYHRLCPIGAPGELLIEGPGLAREYLNDSTKTKA 2033
                   **************96..59*************88555555566667*******9999998888999***************************** PP

                   HEEE............T.CCEEEEEEEEEEETTSEEEEEEECCCEEEET CS
  AMP-binding  388 afds............e.grwlrTGDlgrldedGyleivgRkkdliklr 423 
                   af++            +  r +rTGDl+r ++dG+l ++gR + ++k+r
   EEA19311.1 2034 AFVEdaafvekfgssaGtRRIYRTGDLVRQNTDGSLTYLGRRDTQVKIR 2082
                   ***8899******9873356***************************96 PP

  == domain 3  score: 246.2 bits;  conditional E-value: 1.3e-76
                   HHHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEEE CS
  AMP-binding    4 qaaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakvli 99  
                    a+ +p+ va+     + ++TY+el+  +++l++ L+++Gvk+++ +++++ +s    +a+lail  G+ v pl  + +  +++ il d+ a++l+
   EEA19311.1 2775 VARAQPGLVAIEA--WDGSFTYHELETLARALSQKLKNMGVKPDTLIGVCMSKSKWAAIAMLAILHSGGGVLPLGIQHPISRIQDILVDTAATILL 2868
                   6788999999966..7889***************************************************************************** PP

                   ETCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHHHH CS
  AMP-binding  100 atvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslklet 195 
                      d+e++e+ +++++      ++i++d+  ++  +       s+e    ++  + ++p+++a +iYTSG+TG+PKGV l+hr+l+++++ +   +
   EEA19311.1 2869 --ADQEQAERFQNVTQ------SIIIVDELLFESLD------VSAE----ETVISDVEPHNIAWVIYTSGSTGTPKGVLLEHRSLCSSIQGH--GP 2944
                   ..88888777666665......47888854443332......2222....22455789******************************9996..67 PP

                   CSCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEEEE CS
  AMP-binding  196 rfklkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvllg 291 
                    f+lk++ ++++++ + +++++  ell +l+ G++v+++++d++   ++l+e+i+++kv+++ ++ + +  l             d + ++ +ll 
   EEA19311.1 2945 AFGLKKNTRMFQFAAYTFDVSI-QELLSTLIYGGCVCIPSEDQR--MGALAETINNFKVNLLGLTSSTASLLRPL----------DVPTVQRLLLF 3027
                   799999***************7.***************998877..6799**********999999998888555..........788999999** PP

                   SS-EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTT.SCBEETTSEEEEEEEETTS-SEBTT-HHHHH CS
  AMP-binding  292 geplspellrffralfgeevlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeet.gepvpdgeeGellvrgpgvmkgYlkkpeata 386 
                   ge++ p++++++++++   v+ +YG++E++++ t+ ++ ++++ +  +G+p+ g  + i+D+++ +++vp g +Ge+l+ g  +++gYl++p +t+
   EEA19311.1 3028 GEAVKPSVVEAWSSVG---VYSAYGPSECSMHSTCSEPLTSTVEAANIGRPFSG-NIWIADPKDcNRLVPVGAPGEILIEGSLLARGYLNDPVKTQ 3119
                   ***************6...9*************99777788888999****998.899999877256779************************** PP

                   HHEEE...........TCC.EEEEEEEEEEETTSEEEEEEECCCEEEET CS
  AMP-binding  387 eafds...........egr.wlrTGDlgrldedGyleivgRkkdliklr 423 
                    +f++           +gr ++rTGD++r ++dG++ ++gR + +ik+r
   EEA19311.1 3120 GSFINdpsfirqlglePGRrMYRTGDIARQNADGSFTYLGRRDTQIKIR 3168
                   ****7789******954666***************************96 PP

>> Condensation  Condensation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.8   0.2   3.9e-42   1.4e-38       3     456 ..     164     581 ..     162     582 .. 0.85
   2 !  135.6   0.0   5.3e-43   1.9e-39       2     449 ..    1244    1659 ..    1243    1666 .. 0.80
   3 !  140.4   0.0   1.9e-44   6.7e-41       2     454 ..    2333    2751 ..    2332    2754 .. 0.80
   4 !  101.1   0.0   1.6e-32   5.9e-29      28     446 ..    3439    3832 ..    3417    3838 .. 0.79

  Alignments for each domain:
  == domain 1  score: 132.8 bits;  conditional E-value: 3.9e-42
                   EEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE....TTEEEEEE-TT-----EEEE-T..TSSSHHH CS
  Condensation   3 deyplspaQkrmwflekleeessaynmqavlklegeldlerlekalqelierhdaLRtvfle..eengepvQvileerevelevleisdleeseeee 97 
                    ++p sp+Q+ ++  + +++  + +  ++ +kl+   d + + + + +++++  +LRtvf+    + g++ Qvil + e ++++++++   +s   +
    EEA19311.1 164 AIVPCSPLQEKTLLGQAISPVAYQCSFTIRVKLSIDHDMQSVGDLWSTIVSQRSILRTVFIDsvAQPGHFDQVILRHVEPNVRLIDAT---GSP--D 255
                   67899*************97766666666666666667779*******************9855599******************999...343..2 PP

                   HHHHHHHHH.HTC--SCCCS-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHHHHH CS
  Condensation  98 aieefaqkd.lqepfdLekgpLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskdlek 193
                   +++   ++  + e+f++  +     ++ kia+++++l l++ H ++DG S ++llrd+a+l       ++ +    + Y+dy+  +q+    +  + 
    EEA19311.1 256 DLDLESRRPvIPEKFKVPHC----LHVTKIATREFYLKLDISHSLIDGHSAEVLLRDMASLL----FDRNGRREILS-YRDYVAYYQK---VESKQV 340
                   35555554326677776654....6889999*****************************99....44554444555.*******666...444468 PP

                   HHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEESSTTCSTCHHC CS
  Condensation 194 eeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisgReseikdier 290
                   +++YW+ + ++ + ++ +p  k++ + r+++    +++++ ++++ l+ ++++++vt+ ++ + a+gl+L  ytgq+ + ++ ++s Re + ++i +
    EEA19311.1 341 ASQYWQYYTAN-ARETHVPMLKDQEPMRDLQ----TLRFAFDITSDLNHFCESHKVTIANICQVAWGLVLRYYTGQESVSFSYITSTREAPLSGIMD 432
                   899***99997.5667777776788888888....56666699****************************************************** PP

                   --SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEECCCCSEEECEE...E.. CS
  Condensation 291 mvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeeesqlselklsvssveaee 387
                   ++G ++ntl   +++ ++++ s++++ v ++ l++++hq+   ++     +++ +        +v+sf          + + +s ++l+++++ a +
    EEA19311.1 433 AIGPYINTLLCAMQL-GSQKVSDVLSHVSQEYLQSLKHQNEFSQSF--SARQWGN--------TVMSFRR------NLTRELESIMGLELDIIDAYS 512
                   **********99999.7777***************99998555555..4555665........8999954......577777778888888888999 PP

                   ...SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTTSBCCC-----HHHHHHH CS
  Condensation 388 eskydlsleasetngkltikieYntslFdeetierflerlkelleqviehpeqklselkllsdaekekL 456
                    ++ydlsl+++  + ++ ++++Y  s  d +  + +l+ ++e++++vi++p + ++ l+ll+ + ++++
    EEA19311.1 513 PTDYDLSLNIQAGQYRIDVSMDYWLSKMDAHYADALLKSFREAINCVISQPFANVEGLDLLPREHRAQI 581
                   ***************************************************************999987 PP

  == domain 2  score: 135.6 bits;  conditional E-value: 5.3e-43
                    EEEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-.TT-----EEEE-T..TSSSH CS
  Condensation    2 qdeyplspaQkrmwflekleeessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvil.eerevelevleisdleesee 95  
                    +d+yp +p+Q+++  + +   +++ay+   v+ ++  +d++rl++a+q+l +  ++LRt++l ++ g+ vQv+    + +e+        ++++ 
    EEA19311.1 1244 EDVYPCTPLQEGLMAITM--HQPTAYVSRRVFSMSNDIDIDRLKQAWQTLSDSAPVLRTRILVDQAGDSVQVLIrAPSVIEW-----H--QGNDL 1329
                    799*********877765..569*************************************************9834444555.....4..56665 PP

                    HHHHHHHHHHHHTC--SCCCS-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHH CS
  Condensation   96 eeaieefaqkdlqepfdLekgpLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskd 190 
                    ++ i++ ++    +++  + +pL+r++l++ ++   +++++ HH + DG+S g++ +   ++Y     +++   pq+ p+ ++       l + d
    EEA19311.1 1330 TSYIDQDQR----QGIT-YGQPLVRFGLVSETAGDRYFIWTAHHSVYDGWSAGLMYKYVVSIY-----QSQ-VVPQSVPFTRFLRY----LSQSD 1409
                    555555555....5665.456******************************************.....333.33334446666555....77789 PP

                    HHHHHHHHHHHHH......S.---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEESSTTC CS
  Condensation  191 lekeeaYWseqlegelpvlq.LpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisgRese 284 
                    + k++a+W++qleg  +v   +p+   ++a+++ k  r+++  d ++ + +r +         +vl aa++l+L +y g +d+v+ ++ sgR  +
    EEA19311.1 1410 IDKSAAFWRKQLEG--DVSGnFPPL--PTANYQPK-PRQRLLYDLKVSSPVRLVVGP-----STVLRAAWALALAQYMGLSDVVFAVTLSGRSAP 1494
                    **************..433347777..44444444.455666688999999998665.....689****************************** PP

                    STCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEECCCCSEEEC CS
  Condensation  285 ikdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeeesqlselkls 379 
                    + +i + +   + t+P+ri ++ a    +++++++ +++++ p + ++l++++k +    +      ++  f+ + +  +e+ ++ + l  ++  
    EEA19311.1 1495 VRNITELIAPTITTVPVRIAINTAMGIRDFFTQLQSQVVETIPFEHTGLQNIKKLMPDLSD---ALEINNLFVVQPTSEKEQATSFPGLVPQDDA 1586
                    ****************************************************777775444...4449******996666666666655544444 PP

                    EE....E.....SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTTS...BCCC----- CS
  Condensation  380 vssve.aeeeskydlsleasetngkltikieYntslFdeetierflerlkelleqviehpeq...klselklls 449 
                    +s+   +++    ++sl  s+ ++   +++ Y  +  +e++++r+++++ ++++q+ e+ +q    ++++++l+
    EEA19311.1 1587 LSVNAfHSHPLVVECSLPTSP-SQPVAVEVTYDDNIISEAEVSRIIRQFDHIVSQISEKAAQgnqSIASIDMLN 1659
                    454455567777788888888.999*******************************876655000555555555 PP

  == domain 3  score: 140.4 bits;  conditional E-value: 1.9e-44
                    EEEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T..TSSSHH CS
  Condensation    2 qdeyplspaQkrmwflekleeessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvileerevelevleisdleeseee 96  
                    +d+yp +p+Q+++  +   +++++ay+   +++l+ e+d+erl  a+q + +  ++LRt+++ een + +Qv+ +e ++++     s   +   e
    EEA19311.1 2333 EDIYPSTPLQEGLTAI--TMRQPHAYVSRRIFELTDEVDVERLCAAWQVMSDATPILRTRIVLEENARALQVVVKE-PISW-----S---R---E 2413
                    799*******997655..56789**************************************************865.6666.....4...2...3 PP

                    HHHHHHHHHHHTC--SCCCS.-SEEEEEEESS.TTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSH CS
  Condensation   97 eaieefaqkdlqepfdLekg.pLfraalfkia.enrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqylesk 189 
                    + ++++++k   ++  ++ g pL+r +l++ + + + +++++ HH + DG+S+++l ++ a++Y    +++ +p     pY +++       +s 
    EEA19311.1 2414 KNLDNYLRK--DRSCGIDPGmPLVRYGLVDDQqSGKKFFIWTAHHSVYDGWSMQLLYQSVASIY----SNDIIPH--GIPYTQFIRY----INSI 2496
                    45899***7..5566667777********85415578999************************....7777766..3347777776....6667 PP

                    HHHHHHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEESSTTC CS
  Condensation  190 dlekeeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisgRese 284 
                    d  ++ +YW++ql+ge+  +q+p+   ++ak+++k    + +l++ +++    + ++q+v+  +++ aa++l+  + tg +d+ +g++ sgR+ +
    EEA19311.1 2497 DSASATSYWRNQLSGEEVLAQFPPL--PKAKYQAK---PRYSLQHRMQS--APANQAQNVSSSNLMRAAWALTVMQFTGVNDVLFGVTLSGRTAP 2584
                    77899**********8877778888..55555555...55666555555..5678999************************************* PP

                    STCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEECCCCSEEEC CS
  Condensation  285 ikdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeeesqlselkls 379 
                    + +i +m+   + t+P+ri ++++++ s+++++v++++ +++p++ ++ +++++ + +    + +  ++++f  +     e++e++ q+++lk++
    EEA19311.1 2585 VTGITEMIAPTLTTVPVRISLNPSQSVSKFLESVQKQAIEMMPYEHTGIQKIRELVPELAP-QLE--LNHIFLTQP---VEESEKTLQFRGLKPR 2673
                    ****************************************************888885554.233..566666655...3777777888888888 PP

                    .EE...E.....SSEEEEEEE...TTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHH.HSTTSBCCC-----HHHHH CS
  Condensation  380 .vssveaeeeskydlslease...tngkltikieYntslFdeetierflerlkelleqvi.ehpeqklselkllsdaeke 454 
                      + +e  +  + +l +e +    ++    +++++  ++ +e +++r+++++ +++ q+  ++ +  +++l++l++ + +
    EEA19311.1 2674 dEDDSE--SFHSQALIIECTLgkeSDPHAIVDVKFDDAVISEVEVSRLIRQFDHTVGQLNhANSSILVKDLNILNEYDSR 2751
                    334444..222223333332232366777799999999999999999999999999887514555667777777776655 PP

  == domain 4  score: 101.1 bits;  conditional E-value: 1.6e-32
                    EEEEEEEEES-..--HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T..TSSSHHHHHHHHHHHHHTC--SCCCS-SEE CS
  Condensation   28 nmqavlklege..ldlerlekalqelierhdaLRtvfleeengepvQvileerevelevleisdleeseeeeaieefaqkdlqepfdLekgpLfr 120 
                    ++ +++k++g+   d++ l+k+ + l +  +a+Rtv++ +  ++ +Qv+l++ + ++ +le+   e  +  +a++++    +q p++L + +L+ 
    EEA19311.1 3439 VEVHYFKIDGNspYDVDHLQKVCYGLCNSIEAFRTVYMFH-GDRLLQVVLDTYQQNIPILEVD--ESLD--AATSQLHD-SQQGPLKLGS-SLVE 3526
                    55567777766336999********************888.****************999999..3333..44555544.6889999976.6899 PP

                    EEEEESS.TTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHHHHHHHHHHHHHHH......S---B CS
  Condensation  121 aalfkia.enrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskdlekeeaYWseqlegelpvlqLpkd 214 
                    + l++++ + ++ +l+++ H i DG+S++i+ + ++++Y     ge+  +++ t++++y  +      s+  e++  YW+++l++     ++p+ 
    EEA19311.1 3527 ITLLRRKgTLEHRILFRMSHAIYDGMSFPIIWQTFQRIY----AGES--TLPNTDFSQYLYR----ISSNLEETSYGYWRNLLKR----SSMPQL 3607
                    99998762569****************************....8888..566777******9....55566666889*******8....455555 PP

                    ..SS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEESSTTCS.TCHHC--SS-EEEEEEEEE-- CS
  Condensation  215 ..karpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisgResei.kdiermvGlFvntlPlridvk 306 
                      +++++++  +    ++    ++++      + +g+t   +  aa++l+L  + g+ d+v+g ++sgR+ ++  ++++++G     +Plri+v+
    EEA19311.1 3608 sdSRSLQDQAPR--AMQFC---AIKKVPVGRLSISGMTNAIIVKAAWALALGHVVGTPDVVFGDTVSGRNVPNgTTFDNVIGSCATHVPLRINVQ 3697
                    111444444444..22332...34444456667899999********************************542699****************** PP

                    TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-.SSSS-S-SEEEEESSS-HH....CCCEEECCCCSEEECEE...E.....SSEEEE CS
  Condensation  307 eaktfselikrvkedllkaephqgypleeLvkdlelqrk.esrspLfdpvfsfenylgq....eseeeesqlselklsvssveaeeeskydlsle 396 
                    ++ t  +l+ +v+++  + +p+++ ++ ++++++ ++   +  + ++++ +    + ++    +   e ++ +++ ++           yd+++ 
    EEA19311.1 3698 NSRTGVDLLLAVQDQHFERMPYENLGFRSIINHCTEWLPsTRFTSIVNHRLAN-PTSINlggnNYTVENWMPDAGRMT---------NLYDIAVV 3782
                    ***********************************997503334444444433.222224443555555555555555.........79****** PP

                    EEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTTSBCCC-- CS
  Condensation  397 asetngkltikieYntslFdeetierflerlkelleqviehpeqklselk 446 
                      e +g l++++  ++   ++ +   +le l +++ ++ ++pe++++el 
    EEA19311.1 3783 SEEIDGHLELTLGCAEGTMSSDEAGSLLELLCTAVGMLSSKPESPINELA 3832
                    *********************************************99975 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.1   0.2   2.3e-09   8.4e-06       2      65 ..      31      93 ..      30      95 .. 0.95
   2 !   43.3   0.0     1e-14   3.6e-11       3      67 .]    1137    1201 ..    1135    1201 .. 0.95
   3 !   42.1   0.1   2.2e-14     8e-11       2      67 .]    2227    2291 ..    2226    2291 .. 0.94
   4 !   42.8   0.2   1.4e-14   5.1e-11       2      64 ..    3308    3369 ..    3307    3370 .. 0.97
   5 !   24.5   0.0     7e-09   2.5e-05       3      64 ..    3868    3931 ..    3866    3934 .. 0.85

  Alignments for each domain:
  == domain 1  score: 26.1 bits;  conditional E-value: 2.3e-09
  PP-binding  2 klrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaa 65
                 l++l a++l+ ++++id + ++  lG+DSllav ++a+l+e  g+ i+++d++   ++a+l++
  EEA19311.1 31 FLKDLYADLLKKNASQIDHNRSFLGLGGDSLLAVFVIARLREN-GFMIEVADVLLDGSIAQLSQ 93
                689999*************************************.*********999***99997 PP

  == domain 2  score: 43.3 bits;  conditional E-value: 1e-14
  PP-binding    3 lrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaayl 67  
                  l+ l+aevlgv+l +i+ ++++ + G+DS++a++++   +++fg++++++ +f hp l++la +l
  EEA19311.1 1137 LQYLWAEVLGVSLTDIGTNDSFLEIGGDSITAIRMVDVSQKKFGLRMTVANIFLHPRLKDLATLL 1201
                  6669*********************************************************9875 PP

  == domain 3  score: 42.1 bits;  conditional E-value: 2.2e-14
  PP-binding    2 klrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaayl 67  
                   +++l+a+++++++++i++++++  lG+DS++a++l+ a  ++ + +++++d+f+h+ l+++++++
  EEA19311.1 2227 DIQSLWAQIFKLDTKDIGLQDSFMQLGGDSITAIRLVEA-GRKVNYQLTVADIFAHTKLEDMINFV 2291
                  6899***********************************.6666******************9886 PP

  == domain 4  score: 42.8 bits;  conditional E-value: 1.4e-14
  PP-binding    2 klrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaela 64  
                  +lr+l+a+vl++++  i+ ++d+f+lG DS+la++l++a + + g++++   +f ++tl+ +a
  EEA19311.1 3308 TLRSLWADVLQIDQVTIGSEDDFFSLGADSILAMRLIGASNSR-GIKLDIKNVFRNSTLEKMA 3369
                  69*************************************9999.***************9986 PP

  == domain 5  score: 24.5 bits;  conditional E-value: 7e-09
  PP-binding    3 lrelvaevlgv....pleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaela 64  
                  + +++++v+g     ++++++ ++++ dlG+D ++a++l++  +++ g+ i+l+dl+ +++l+ ++
  EEA19311.1 3868 IFDIWQSVFGNkrvvEHSSLS-SSPFHDLGGDLVDAAQLVSTAQQH-GINITLDDLLKYSSLEKMV 3931
                  667888888865555666666.999********************9.***************9997 PP

>> AMP-binding_C  AMP-binding enzyme C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.9   0.0    0.0073        26      44      76 .]    1066    1098 ..    1034    1098 .. 0.88
   2 !    8.4   0.0    0.0012       4.3      44      76 .]    2157    2189 ..    2132    2189 .. 0.82
   3 !   10.1   0.0   0.00035       1.3      44      76 .]    3238    3270 ..    3214    3270 .. 0.85

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0073
                     HHHHHHHHHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   44 eeLkahvrkelgpyavpkkvvfvdelpktrsGK 76  
                     + L++++ ++l++y+vp+  v ++++p+t s K
     EEA19311.1 1066 QRLRERLLEKLPSYMVPSVYVPLADMPLTLSTK 1098
                     67999999**********9999999****8876 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0012
                     HHHHHHHHHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   44 eeLkahvrkelgpyavpkkvvfvdelpktrsGK 76  
                     + +++++ ++l++y+ p++ v   ++pkt +GK
     EEA19311.1 2157 QSIRDFLSTKLPAYMIPSTYVPMLQVPKTVTGK 2189
                     789***************8886668*******9 PP

  == domain 3  score: 10.1 bits;  conditional E-value: 0.00035
                     HHHHHHHHHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   44 eeLkahvrkelgpyavpkkvvfvdelpktrsGK 76  
                      +L++ +r++l++y+vp ++v  +++p ++sGK
     EEA19311.1 3238 TALREALRQKLPSYMVPTAFVPFAKIPFNASGK 3270
                     689***************9997778*******9 PP

>> AATase  Alcohol acetyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0      0.38   1.4e+03     164     203 ..     293     333 ..     291     339 .. 0.80
   2 ?    1.1   0.0     0.032   1.1e+02     142     182 ..    1348    1385 ..    1340    1412 .. 0.82
   3 ?    5.5   0.0    0.0014       5.1     121     181 ..    2414    2472 ..    2408    2477 .. 0.80
   4 ?   -1.4   0.0      0.18   6.3e+02     156     206 ..    3536    3587 ..    3527    3591 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.38
      AATase 164 dHllfDGisgvnffkdlleelekikqdna.lkkdevildye 203
                  H+l DG s+  +++d++  l   ++    l+  +++  y+
  EEA19311.1 293 SHSLIDGHSAEVLLRDMASLLFDRNGRREiLSYRDYVAYYQ 333
                 5*****************99887777666577777777665 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.032
      AATase  142 wrlivlpsaddkkkwkkfvfitdHllfDGisgvnffkdlle 182 
                   r  ++ +  ++   + f++   H++ DG s+ +++k+++ 
  EEA19311.1 1348 VRFGLVSETAGD---RYFIWTAHHSVYDGWSAGLMYKYVVS 1385
                  555555555444...6789******************9975 PP

  == domain 3  score: 5.5 bits;  conditional E-value: 0.0014
      AATase  121 eelnellselvipvgdpkkPlwrlivlpsaddkkkwkkfv.fitdHllfDGisgvnffkdll 181 
                  ++l + l++  ++  dp  Pl r  ++ +++++   kkf  +   H++ DG s  ++++ ++
  EEA19311.1 2414 KNLDNYLRKDRSCGIDPGMPLVRYGLVDDQQSG---KKFFiWTAHHSVYDGWSMQLLYQSVA 2472
                  566677777788888899999999999887555...66555******************987 PP

  == domain 4  score: -1.4 bits;  conditional E-value: 0.18
      AATase  156 wkkfv.fitdHllfDGisgvnffkdlleelekikqdnalkkdevildyekdv 206 
                   ++ + f + H + DG+s + +++         ++ +  ++ +++++ +++ 
  EEA19311.1 3536 LEHRIlFRMSHAIYDGMSFPIIWQTFQRIYAGESTLPNTDFSQYLYRISSNL 3587
                  556676******************9999888888888889999998887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (3936 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       554  (0.0308997); expected 358.6 (0.02)
Passed bias filter:                      504  (0.0281109); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 1.52u 0.33s 00:00:01.85 Elapsed: 00:00:00.53
# Mc/sec: 22351.39
//
Query:       EEA19312.1  [L=573]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (573 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       495  (0.0276089); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.40
# Mc/sec: 4312.25
//
Query:       EEA19313.1  [L=154]
Description: mitochondrial inner membrane translocase subunit (TIM17), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    9.5e-31  106.5   7.5    1.2e-30  106.2   7.5    1.1  1  Tim17        Tim17/Tim22/Tim23/Pmp24 family
  ------ inclusion threshold ------
      0.076   13.2   0.0       0.13   12.5   0.0    1.5  1  HATPase_c_4  Putative ATP-dependent DNA helicase recG C-termi


Domain annotation for each model (and alignments):
>> Tim17  Tim17/Tim22/Tim23/Pmp24 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.2   7.5   1.3e-34   1.2e-30       3     111 .]      14     120 ..      12     120 .. 0.96

  Alignments for each domain:
  == domain 1  score: 106.2 bits;  conditional E-value: 1.3e-34
       Tim17   3 yktglsgvlGallGavfglvkgsrradtpapskerlreglrsvgkrgpslGknfgvvgglysgiecaleklRgkediwnsvaAGaltGall..ragpqa 99 
                 +++g+++ +Ga++Gav++ vkg+r+++    ++er+  ++ ++++r+p lG+nfg++ggl+s+ +c ++++R+ked++n+++AG+ltG+ l  r+g++a
  EEA19313.1  14 SDFGGAFCMGAIGGAVWHGVKGFRNSP----YGERRIGAITAIKARAPVLGGNFGAWGGLFSIYDCSVKGIRKKEDPYNAIIAGFLTGGSLaiRGGYKA 108
                 789**********************99....9**********************************************************9556***** PP

       Tim17 100 aavgaiggaafs 111
                 a ++ai++a+f+
  EEA19313.1 109 ARNSAIMCAVFL 120
                 **********95 PP

>> HATPase_c_4  Putative ATP-dependent DNA helicase recG C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   1.4e-05      0.13      33      76 ..     104     146 ..      66     153 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.4e-05
  HATPase_c_4  33 egrssaRNelLasllerlrlmeergsGiqrilealeeaglpepe 76 
                   g ++aRN++++     l ++e  g G+qr+++   +++lp+p 
   EEA19313.1 104 GGYKAARNSAIMC-AVFLAVIEGVGIGFQRMMADNTKLELPPPP 146
                  5568899999985.457899*********************995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (154 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       367  (0.0204696); expected 358.6 (0.02)
Passed bias filter:                      310  (0.0172904); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.30s 00:00:00.72 Elapsed: 00:00:00.45
# Mc/sec: 1031.73
//
Query:       EEA19314.1  [L=1461]
Description: ATP-binding cassette transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.4e-42  144.7   0.0    6.3e-25   88.3   0.0    2.7  2  ABC_tran      ABC transporter
    6.8e-28   98.1   9.1    6.8e-28   98.1   9.1    3.1  2  ABC_membrane  ABC transporter transmembrane region
    3.1e-14   53.0   0.8      2e-05   24.1   0.0    3.8  3  SMC_N         RecF/RecN/SMC N terminal domain
    3.2e-09   37.0   0.2      0.093   12.5   0.0    5.0  5  AAA_21        AAA domain, putative AbiEii toxin, Type IV TA s
    5.7e-09   35.6   1.3    0.00079   19.1   0.0    2.6  2  AAA_29        P-loop containing region of AAA domain
    2.1e-06   28.4   0.3      0.048   14.2   0.0    2.6  2  AAA_23        AAA domain
    6.1e-06   26.7   0.1      0.093   13.1   0.0    2.8  2  AAA_16        AAA ATPase domain
    2.9e-05   24.1   0.6       0.43   10.7   0.2    2.7  2  MMR_HSR1      50S ribosome-binding GTPase
    0.00055   20.2   0.1        1.1    9.5   0.0    3.0  2  AAA_22        AAA domain
    0.00076   19.6   0.2        1.5    8.8   0.1    2.6  2  Dynamin_N     Dynamin family
     0.0013   18.6   0.3       0.93    9.4   0.1    2.4  2  RsgA_GTPase   RsgA GTPase
     0.0016   17.8   0.3       0.99    8.7   0.0    2.3  2  FtsK_SpoIIIE  FtsK/SpoIIIE family
     0.0017   17.5   0.7       0.57    9.2   0.1    2.4  2  T2SSE         Type II/IV secretion system protein
     0.0019   18.0   1.8       0.27   10.9   0.0    2.6  3  AAA_15        AAA ATPase domain
     0.0026   18.3   0.0       0.32   11.5   0.0    2.6  2  AAA_18        AAA domain
     0.0075   16.1   0.7       0.49   10.1   0.1    3.0  3  ATP_bind_1    Conserved hypothetical ATP binding protein
     0.0076   16.4   0.7       0.73    9.9   0.1    2.5  2  DUF87         Helicase HerA, central domain
     0.0099   15.6   1.3        1.7    8.2   0.1    2.5  2  ATP-synt_ab   ATP synthase alpha/beta family, nucleotide-bind
  ------ inclusion threshold ------
      0.014   14.7   0.1       0.43    9.8   0.0    2.3  2  Zeta_toxin    Zeta toxin
      0.018   15.4   0.3        8.9    6.8   0.1    3.4  3  RNA_helicase  RNA helicase
      0.025   14.3   0.2        4.1    7.1   0.0    2.7  2  AAA_30        AAA domain
      0.056   12.2   0.7       0.25   10.1   0.1    2.1  2  ABC_ATPase    Predicted ATPase of the ABC class
      0.071   12.1   0.2       0.24   10.3   0.0    1.8  2  MeaB          Methylmalonyl Co-A mutase-associated GTPase Mea
       0.22   11.0   0.7         12    5.4   0.1    2.4  2  AAA_7         P-loop containing dynein motor region


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.6   0.0   4.3e-17   3.2e-14       2     134 ..     640     772 ..     639     775 .. 0.83
   2 !   88.3   0.0   8.4e-28   6.3e-25       1     137 []    1247    1392 ..    1247    1392 .. 0.95

  Alignments for each domain:
  == domain 1  score: 53.6 bits;  conditional E-value: 4.3e-17
                 EEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH........HHHTC........ CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxx........ RF
    ABC_tran   2 knvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren........esdee........ 84 
                 +n ++++++g++++i G++ +GKStL+k+l++    ++G              +    + g+ +qep l +++ vren        +   +        
  EEA19314.1 640 SNATFTINQGSLTVIQGDTASGKSTLVKALLRVAVVQQGAF------------TPRFPNAGYSSQEPWLMKGT-VRENvvgpskfdA---Kwyemvldc 722
                 689*************************************9............3445678*************.********96541...433344555 PP

                 ..HHHHHHHSTTGGTTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEES CS
                 ..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  85 ..iekalsklglkelkdtvvksspssLSgGqkqrvalarallkkpkllllDE 134
                   ++  +s++g    ++t ++ ++  LSgGq++r+alara+ ++ +++++D+
  EEA19314.1 723 csLNMDISRMGK--GDQTLIGGEGIRLSGGQQSRMALARAVYSRHRVMIFDD 772
                 444444555554..4599999999***************************8 PP

  == domain 2  score: 88.3 bits;  conditional E-value: 8.4e-28
                  EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH......HHHTCHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxx RF
    ABC_tran    1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren......esdeeiekalsk 91  
                  l+++++++++g+k++i G++G+GKS++l++l++ l+   G+i++dg dlk ++   lr++i +lpq++ l p++ +ren       sd e+  +l+k
  EEA19314.1 1247 LEDITFDVEAGQKIGICGRTGSGKSSMLSALSKILQTSRGSITVDGLDLKWISPDTLRERILTLPQNAVLVPGS-IRENvdpsgtLSDPECISFLEK 1342
                  689***********************************************************************.********9999999******* PP

                  STTGGTTCBGESTTS....GGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                  xxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran   92 lglkelkdtvvkssp....ssLSgGqkqrvalarallkkpkllllDEpta 137 
                  +gl e+ ++  + ++    +sLS Gq q +++aral+  ++++++DE t+
  EEA19314.1 1343 VGLWEFLEQQGGLDApaneQSLSAGQSQLLVVARALAHPRSVMMMDEVTS 1392
                  *****88887665556677****************************985 PP

>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.3   7.8   6.5e-05     0.048       2     249 ..     267     507 ..     266     539 .. 0.78
   2 !   98.1   9.1   9.1e-31   6.8e-28       7     242 ..     914    1152 ..     912    1189 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 6.5e-05
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHHHH.SCH CS
  ABC_membrane   2 iliillailagvlsplfplvlgrildtlldkgdpetealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsffdt.nsv 97 
                   i++++  ++  +  + +p++l+r++d+  d ++++    +   +++++++++ ++++ ++ y+ ++    ++  l   lf+k l+++ +  dt   v
    EEA19314.1 267 IAGVIPRLCLIAFTFSQPFLLARVIDHEEDPNSSQA-SRTWDVIAYVVVYVGIALSTGAYMYFTTKFITLIRGGLIGLLFEKALELNPK--DTgEAV 360
                   67888889999999**************99877777.566666666666666677777777777777899999*************776..666778 PP

                   HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHH CS
  ABC_membrane  98 GellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirtVk 194
                   ++ +++l++d+++++ gl++ +      + + +++ +++  lg   t+  + +++ +++   +ia + +k  k    a++k+ ++++ +++ +r Vk
    EEA19314.1 361 SSTITLLNSDTERINLGLQQIHNAYACLIEIGISAWLLARQLGLA-TVGSVLFCFSCVITGNIIATMANKWLKLWLGAIEKRVNFTTHIVNQYRSVK 456
                   8888****************9998877777777777777777774.5555666666667777899999999************************** PP

                   HTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane 195 afgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttl 249
                     g  +   +k    +e++    i++ ++++  i+ +++l+++s+++a ++G+t 
    EEA19314.1 457 MAGFSKLLASKVSWFREDE----IRVSKTYRTYIVGIFSLTYVSNTIAPVLGFTI 507
                   9776666666666665555....55577777777788888888887777777654 PP

  == domain 2  score: 98.1 bits;  conditional E-value: 9.1e-31
                    HHHHHHHHHHHHHHHHHHHHHHHHSS..TCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHHHHHHHCSTHHHHHHSCHH CS
  ABC_membrane    7 lailagvlsplfplvlgrildtlldk..gdpetealnvysllllllglaqfilallqsyllnv.tgerlskrlrrklfkkilrqpmsffdtnsvG 98  
                    +a+la+v+ ++f l++ +il +  ++   +++ +   vy+ ++++lg++++i+      +l+  +  +  ++l++++++ ++r+p+ ++ +++ G
    EEA19314.1  914 AAFLACVVGLVFGLYFPQILISWWTTpgDTTHRWGNGVYLGVYFSLGIFSLICIGSGGLILMLlIVANSASKLHASMIRTLFRAPVLWILQRDDG 1008
                    55666666666666665555444433323333368999****************9999999665******************************* PP

                    HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHH CS
  ABC_membrane   99 ellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirtV 193 
                    ++++r++ d+  ++ +++ + ++ + s lt+++  i++++++ +l +++++ ++++++v++++ +++++l++ + +a+a++ s + E+l+g  t+
    EEA19314.1 1009 DVINRFSQDLGLVDAVVPLSSFVTVFSGLTCIIQAIFICVSSKYLVIAVVGSIFVLYIVQIFYLRTSRQLRILDLEATAPLVSQVLEALQGNTTI 1103
                    *********************************************************************************************** PP

                    HHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane  194 kafgreeyflekfekaleeakkagikkaianglligitqllgllsyala 242 
                    ka+g+e++f+e+  + l++ +k ++    ++++l+ +++l++  + ++ 
    EEA19314.1 1104 KALGWESAFRERQLELLDQSQKPYYLLPMVQRWLGFVLDLIVAGIAVVL 1152
                    ***************************************9987765554 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   5.2e-06    0.0039      60     213 ..     600     824 ..     585     830 .. 0.73
   2 !    7.4   0.1    0.0035       2.6      28      48 ..    1261    1281 ..    1248    1291 .. 0.82
   3 !   24.1   0.0   2.7e-08     2e-05     135     212 ..    1362    1435 ..    1329    1441 .. 0.89

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 5.2e-06
                 CCCCCC--.BTTCSSTTEEEEEEEEEETTEESSSSSSCEEEE.EEEETTSEEEEEETTEEE-H.HH.HHHHHHCTT-STT................... CS
                 xxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxx.xx.xxxxxxxxxxxxx................... RF
       SMC_N  60 klsdlihk.skekasvkkaeveitfdnedkklkiekeevsis.rrvkrkgeseykingkevtk.ke.vsellesagiske................... 135
                 +l+ li++ s++  +  +a+ +i++ ++ +    ++e+  is  +   ++ s   i+g +++  +  v+ ll+ a +++                    
  EEA19314.1 600 ELTGLISSpSHDTFADLSADRTIVIAKNANI-GWDNERAIISnATFTINQGSLTVIQGDTASGkSTlVKALLRVAVVQQGaftprfpnagyssqepwlm 697
                 5566666643444444556666666555555.4455555554044555556788888877765344145555555555559999999999999999999 PP

                 ................................................CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHH CS
                 ................................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 136 ................................................lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkek 186
                                                                  LSgG+++ +ala       ++++ ++++D+i +aLD + ++ + + l ++
  EEA19314.1 698 kgtvrenvvgpskfdakwyemvldccslnmdisrmgkgdqtliggegiRLSGGQQSRMALA----RAVYSRHRVMIFDDIFSALDPATMNTIMTKLFAQ 792
                 999999999999999999999999999999999999999999999999*******977665....557888999************9999887766543 PP

                 .....CTTSEEEEE-SSHHHCCC-SCEEEEEE CS
                 .....xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 187 .....sknaQfivislreemlekadklvgvtk 213
                      + ++ +i++s ++ + + a++++++ +
  EEA19314.1 793 nglfrRLKTSVIIVSNNASLAQLANSILKINS 824
                 12211457899999999999999999999876 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0035
                  EEEESTTSSHHHHHHHHHHHC CS
                  xxxxxxxxxxxxxxxxxxxxx RF
       SMC_N   28 aivGpNGSGKsnlldAilFvL 48  
                   i G+ GSGKs++l A++ +L
  EEA19314.1 1261 GICGRTGSGKSSMLSALSKIL 1281
                  699*************98766 PP

  == domain 3  score: 24.1 bits;  conditional E-value: 2.7e-08
                  TCS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC-SCEEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  135 elLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQfivislreemlekadklvgvt 212 
                  ++LS G+ +L+ +a       ++p++++++De+ + LD+k  + +  ++ke+ +n  +i ++++ e+l ++dk+v + 
  EEA19314.1 1362 QSLSAGQSQLLVVARA----LAHPRSVMMMDEVTSSLDAKTDHLIRGIIKENFQNNTIISVAHKLEHLLECDKVVVIH 1435
                  5799999999766555....568*************************************************999876 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       1.9   1.4e+03     143     199 ..     195     250 ..     187     254 .. 0.86
   2 !   12.5   0.0   0.00012     0.093       1      61 [.     651     712 ..     651     716 .. 0.87
   3 !    7.0   0.0     0.006       4.4     240     300 ..     750     811 ..     742     814 .. 0.74
   4 ?    5.2   0.1      0.02        15       3      25 ..    1261    1283 ..    1260    1313 .. 0.74
   5 ?    5.1   0.0     0.023        17     228     283 ..    1355    1407 ..    1303    1418 .. 0.71

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 1.9
      AAA_21 143 altditsrawsllllldglrkerigllnifadyfgfakekrllqrlvrslklveiel 199
                 a t + s++w l+ l++ ++k ++++l++  ++ + ++ k+  q+++ ++k+v+ + 
  EEA19314.1 195 AGTISLSTFWWLNRLMWLGYK-DSLTLDMLSELDPNMSAKNTSQKFSAGWKRVDQHK 250
                 6688899*************9.99999999999999999999999999999998765 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 0.00012
      AAA_21   1 lnvliGpNgsGKSnLLdaldllarl.drdvegltdelsggggirkipslldlydpeipfefe 61 
                 l+v+ G+ +sGKS+L +al  +a + ++ ++++ ++++ ++++++  +   + +  +p++f 
  EEA19314.1 651 LTVIQGDTASGKSTLVKALLRVAVVqQGAFTPRFPNAGYSSQEPWLMKGTVRENVVGPSKFD 712
                 699****************9999889999999999999999999988888888888888775 PP

  == domain 3  score: 7.0 bits;  conditional E-value: 0.006
      AAA_21 240 GtkrllalltallralkkgsllliDEpEngLHPkllrrll.ell...kelsrngaQviltTHSpl 300
                 G+++  al+ a+++++   ++ ++D++ + L+P+ + +++ +l+    + +r ++ vi+++ + +
  EEA19314.1 750 GQQSRMALARAVYSRH---RVMIFDDIFSALDPATMNTIMtKLFaqnGLFRRLKTSVIIVSNNAS 811
                 5555557777778888...********************99888555333335556777776655 PP

  == domain 4  score: 5.2 bits;  conditional E-value: 0.02
      AAA_21    3 vliGpNgsGKSnLLdaldllarl 25  
                  ++ G+ gsGKS+ L al+ + ++
  EEA19314.1 1261 GICGRTGSGKSSMLSALSKILQT 1283
                  689**************866553 PP

  == domain 5  score: 5.1 bits;  conditional E-value: 0.023
      AAA_21  228 dgqelparelSdGtkrllalltallralkkgsllliDEpEngLHPkllrrllellk 283 
                   + + +  +lS G+ +l  +++  l a++  s+   DE+ ++L+ k  + + +++k
  EEA19314.1 1355 LDAPANEQSLSAGQSQL-LVVARAL-AHPR-SVMMMDEVTSSLDAKTDHLIRGIIK 1407
                  3445555566*******.4444444.3444.*************955555555553 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   1.1e-06   0.00079      14      50 ..     641     677 ..     634     683 .. 0.84
   2 !   14.6   0.3   2.8e-05     0.021      17      48 ..    1252    1283 ..    1242    1289 .. 0.77

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 1.1e-06
      AAA_29  14 ghtieidlkgatlltGpsGsGKSTllDAiqalLvpak 50 
                 + t++i++ + t++ G++ sGKSTl+ A+  + v ++
  EEA19314.1 641 NATFTINQGSLTVIQGDTASGKSTLVKALLRVAVVQQ 677
                 5788998555*******************99988766 PP

  == domain 2  score: 14.6 bits;  conditional E-value: 2.8e-05
      AAA_29   17 ieidlkg.atlltGpsGsGKSTllDAiqalLvp 48  
                  ++++ +g  + + G++GsGKS++l A++ +L  
  EEA19314.1 1252 FDVE-AGqKIGICGRTGSGKSSMLSALSKILQT 1283
                  3444.2357889****************99976 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.0   6.4e-05     0.048      13      39 ..     642     669 ..     634     693 .. 0.83
   2 !   11.3   0.1   0.00048      0.36      21      42 ..    1259    1280 ..    1237    1290 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 6.4e-05
      AAA_23  13 qeidFsk.gltlItGpNGaGKTTildAi 39 
                  ++  ++  lt+I G++ +GK+T++ A+
  EEA19314.1 642 ATFTINQgSLTVIQGDTASGKSTLVKAL 669
                 556665526****************998 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00048
      AAA_23   21 ltlItGpNGaGKTTildAikla 42  
                     I+G +G+GK++ l A+  +
  EEA19314.1 1259 KIGICGRTGSGKSSMLSALSKI 1280
                  458***************9755 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.1   0.0   0.00012     0.093       8      51 ..     635     677 ..     630     703 .. 0.74
   2 !   10.4   0.0   0.00083      0.62      29     157 ..    1262    1404 ..    1245    1416 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 0.00012
      AAA_16   8 eleqLlsalervrsgrpelvllsGesGvGKsslvrellr.alekd 51 
                 e++ + +a  ++++g  +l+++ G+ ++GKs+lv++llr a+ ++
  EEA19314.1 635 ERAIISNATFTINQG--SLTVIQGDTASGKSTLVKALLRvAVVQQ 677
                 555555555556666..799*****************98333333 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00083
      AAA_16   29 lsGesGvGKsslvrellralekdggiflrgkcdqlesaipysalaqalareellrqlldeaesaeleawrekleeala................... 106 
                  + G  G+GKss++ +l + l++++g  +    d            + ++ ++l + +l+ +++a l + + +     +                   
  EEA19314.1 1262 ICGRTGSGKSSMLSALSKILQTSRGSITVDGLDL-----------KWISPDTLRERILTLPQNAVLVPGSIRENVDPSgtlsdpecisflekvglwe 1347
                  6799*************99998853333333333...........3455555556666665555555544444443336677777888888888999 PP

      AAA_16  107 ....avpelagaeasrllellkrllallsrderp.lvlvlDdlq.wadeaslqllaa 157 
                      +++ +a+a +++l +  ++ll+ ++  ++p  v+ +D++   +d+ + +l++ 
  EEA19314.1 1348 fleqQGGLDAPANEQSLSAGQSQLLVVARALAHPrSVMMMDEVTsSLDAKTDHLIRG 1404
                  999888888888889999999999999999999999999999985555555555665 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.7   0.0   0.00058      0.43       3      41 ..     653     690 ..     652     712 .. 0.87
   2 !   10.7   0.2   0.00058      0.43       1      21 [.    1259    1279 ..    1259    1291 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00058
                 EEEESTTSSHHHHHHHHHTSTEEESSSTTSSSSEEEEEE CS
    MMR_HSR1   3 aivGrpNvGKStLinaltgekaivsdkpgtTrdinegrv 41 
                 +i G + +GKStL++al++ +a v++ ++t r +n g  
  EEA19314.1 653 VIQGDTASGKSTLVKALLR-VAVVQQGAFTPRFPNAGYS 690
                 678999************8.7899999999999998865 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 0.00058
                  EEEEEESTTSSHHHHHHHHHT CS
    MMR_HSR1    1 evaivGrpNvGKStLinaltg 21  
                  +++i Gr+ +GKS++++al++
  EEA19314.1 1259 KIGICGRTGSGKSSMLSALSK 1279
                  699****************87 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.1   0.0    0.0086       6.4       4      30 ..     648     674 ..     646     694 .. 0.85
   2 !    9.5   0.0    0.0015       1.1      10     100 ..    1262    1390 ..    1255    1426 .. 0.65

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0086
      AAA_22   4 tagilvvtGesGtGKTtllrrlleqld 30 
                 + +++v+ G + +GK+tl++ ll+ ++
  EEA19314.1 648 QGSLTVIQGDTASGKSTLVKALLRVAV 674
                 578899***************998765 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.0015
      AAA_22   10 vtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsst..sskdllrellralglelka.................................. 70  
                  ++G +G+GK+  l  l + l+        +++ ++v+   ++  s+++l++++l   ++                                      
  EEA19314.1 1262 ICGRTGSGKSSMLSALSKILQT-------SRGSITVDGLDLKwiSPDTLRERILTLPQNAVLVpgsirenvdpsgtlsdpecisflekvglwefleq 1351
                  8*****************9975.......77777777777778888888888776555333335555555555555555555555555555555555 PP

      AAA_22   71 ........erlsseellealeqalrarav.ielliiDEa 100 
                          +++s+++  ++l   +ra a  +++++ DE+
  EEA19314.1 1352 qggldapaNEQSLSAGQSQLLVVARALAHpRSVMMMDEV 1390
                  555554444444444445555555554445666666665 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.9   0.0    0.0038       2.9       3      26 ..     654     677 ..     652     712 .. 0.84
   2 !    8.8   0.1     0.002       1.5       1      32 [.    1260    1289 ..    1260    1307 .. 0.81

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0038
                 EEEBTTTTHHHHHHHHHTS--S-- CS
   Dynamin_N   3 vvGsqSsGKSSvlnaLlgedilpr 26 
                 + G++ sGKS+++ aLl+ ++   
  EEA19314.1 654 IQGDTASGKSTLVKALLRVAVVQQ 677
                 669**************9996543 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.002
                  EEEEEBTTTTHHHHHHHHHTS--S---SSS-- CS
   Dynamin_N    1 iavvGsqSsGKSSvlnaLlgedilprgpnptT 32  
                  i ++G + sGKSS+l aL +  il ++ + +T
  EEA19314.1 1260 IGICGRTGSGKSSMLSALSK--ILQTSRGSIT 1289
                  789***************75..5555555555 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.8   0.0    0.0075       5.6      98     122 ..     648     672 ..     611     682 .. 0.83
   2 !    9.4   0.1    0.0012      0.93      88     129 ..    1245    1287 ..    1228    1292 .. 0.79

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0075
                  TTSEEEEECSTTSSHHHHHHHHCTT CS
  RsgA_GTPase  98 kdktsvlvGqSGvGKStLinallpe 122
                  +++++v+ G +  GKStL++all  
   EEA19314.1 648 QGSLTVIQGDTASGKSTLVKALLRV 672
                  4599*****************9865 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.0012
                   TTHHHHHHHCTT.SEEEEECSTTSSHHHHHHHHCTT-----S- CS
  RsgA_GTPase   88 egleelkellkd.ktsvlvGqSGvGKStLinallpelelktge 129 
                   + le+++  ++  + + ++G +G GKS+++ al   l+++ g+
   EEA19314.1 1245 DVLEDITFDVEAgQKIGICGRTGSGKSSMLSALSKILQTSRGS 1287
                   55677777777768889***************99877666555 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.8   0.0     0.005       3.7      33      64 ..     646     674 ..     632     679 .. 0.75
   2 !    8.7   0.0    0.0013      0.99      41      59 ..    1259    1277 ..    1240    1282 .. 0.82

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.005
                   EEGGGS-.SEEEE--TTSSHHHHHHHHHHHHH CS
  FtsK_SpoIIIE  33 ldlkkmashllvaGatgsGKStalntLilSla 64 
                   +++ + +   ++ G t sGKSt +++L+  ++
    EEA19314.1 646 INQGSLT---VIQGDTASGKSTLVKALLRVAV 674
                   4444444...9****************86655 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.0013
                    SEEEE--TTSSHHHHHHHH CS
  FtsK_SpoIIIE   41 hllvaGatgsGKStalntL 59  
                     + ++G+tgsGKS +l +L
    EEA19314.1 1259 KIGICGRTGSGKSSMLSAL 1277
                    6779************987 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.2   0.0    0.0063       4.7     128     152 ..     648     672 ..     609     679 .. 0.85
   2 !    9.2   0.1   0.00076      0.57     127     160 ..    1255    1288 ..    1235    1292 .. 0.83

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0063
       T2SSE 128 erglilvsGgTgsGKttllyallke 152
                 +  l ++ G T sGK+tl+ all  
  EEA19314.1 648 QGSLTVIQGDTASGKSTLVKALLRV 672
                 44567899*************9975 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00076
       T2SSE  127 rerglilvsGgTgsGKttllyallkeinksderi 160 
                  ++ + i + G TgsGK+ +l al k++++s   i
  EEA19314.1 1255 EAGQKIGICGRTGSGKSSMLSALSKILQTSRGSI 1288
                  555677899******************9995544 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0     0.015        11      17      44 ..     644     670 ..     639     713 .. 0.90
   2 ?   -2.8   0.8       5.2   3.9e+03     184     227 ..     843     906 ..     780     913 .. 0.52
   3 !   10.9   0.0   0.00037      0.27      25      50 ..    1259    1284 ..    1247    1323 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.015
      AAA_15  17 veidlseeltvliGkNnsGKSsileald 44 
                 ++i+  + ltv+ G  +sGKS++++al 
  EEA19314.1 644 FTINQGS-LTVIQGDTASGKSTLVKALL 670
                 4566556.******************95 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 5.2
      AAA_15 184 e....................elknvlksaiiklllisakRnvsdedsekkssllgklkekile 227
                                      e++++ +sa + l+ + +  + ++e+ +k+++  +k+++ +++
  EEA19314.1 843 LrvsdnefafnafaptlslqtEKSQFTNSAVTVLQADDENPETKNEKGKKQEKGNDKVYRYYFK 906
                 1333333333333333444445555555555555555555555555555555555555555554 PP

  == domain 3  score: 10.9 bits;  conditional E-value: 0.00037
      AAA_15   25 ltvliGkNnsGKSsilealdlFlnnk 50  
                     ++G+ +sGKSs l al ++l+++
  EEA19314.1 1259 KIGICGRTGSGKSSMLSALSKILQTS 1284
                  5669********************99 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.097        73       3      19 ..     654     670 ..     653     704 .. 0.87
   2 !   11.5   0.0   0.00043      0.32       1      47 [.    1260    1303 ..    1260    1409 .. 0.66

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.097
      AAA_18   3 ltGtpGvGKttlakeLs 19 
                 + G  ++GK+tl k+L 
  EEA19314.1 654 IQGDTASGKSTLVKALL 670
                 78999**********94 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 0.00043
      AAA_18    1 IlltGtpGvGKttlakeLskrlgfgvnlrdvakenglllevdpeald 47  
                  I+++G  G+GK+++  +Lsk l   + +r  ++ +gl l +  +++ 
  EEA19314.1 1260 IGICGRTGSGKSSMLSALSKIL---QTSRGSITVDGLDLKWISPDTL 1303
                  89******************97...4444444444444444444333 PP

>> ATP_bind_1  Conserved hypothetical ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0      0.99   7.4e+02     129     183 ..     519     575 ..     514     621 .. 0.69
   2 ?    1.8   0.0      0.22   1.7e+02       2      19 ..     655     672 ..     654     678 .. 0.83
   3 !   10.1   0.1   0.00065      0.49       1      27 [.    1262    1288 ..    1262    1294 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.99
  ATP_bind_1 129 LvDsqrltdptkfisgllsalsamlrlelPhvvvlnkfDllkek..lekeleffedv 183
                 ++Ds+r+ ++ + +s l +++s+ ++  l   ++l +f+  +++   e++ + ++ +
  EEA19314.1 519 VLDSTRAFSALTVFSLLTQSVSMFIQSILEVMNCLGCFERYQKYlaGEEQSKEVNAP 575
                 6899***********************************999776533444433333 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.22
  ATP_bind_1   2 vGpaGsGKttfvgalsei 19 
                  G   sGK+t+v+al  +
  EEA19314.1 655 QGDTASGKSTLVKALLRV 672
                 58899********99876 PP

  == domain 3  score: 10.1 bits;  conditional E-value: 0.00065
  ATP_bind_1    1 vvGpaGsGKttfvgalseilelrgrsv 27  
                  ++G  GsGK+++ +als+il+++  s+
  EEA19314.1 1262 ICGRTGSGKSSMLSALSKILQTSRGSI 1288
                  68*******************995544 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.0     0.058        43      28      48 ..     654     674 ..     652     682 .. 0.83
   2 !    9.9   0.1   0.00097      0.73      23      47 ..    1257    1281 ..    1245    1290 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.058
       DUF87  28 ilgsTGsGKSntvavLleell 48 
                 i g T sGKS++v+ Ll+ ++
  EEA19314.1 654 IQGDTASGKSTLVKALLRVAV 674
                 568999***********9777 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.00097
       DUF87   23 trHlAilgsTGsGKSntvavLleel 47  
                   + ++i g+TGsGKS   + L + l
  EEA19314.1 1257 GQKIGICGRTGSGKSSMLSALSKIL 1281
                  5789************999887655 PP

>> ATP-synt_ab  ATP synthase alpha/beta family, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.1     0.014        11       6      38 ..     641     673 ..     637     681 .. 0.89
   2 !    8.2   0.1    0.0023       1.7       6      40 ..    1249    1283 ..    1243    1294 .. 0.84

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.014
                  HHHS-EBTT-EEEEEESTTSSHHHHHHHHHHHS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab   6 DalfpivqGqrtlipgafgvGktvisqslskqs 38 
                  +a f+i qG  t+i g+   Gk++++++l++ +
   EEA19314.1 641 NATFTINQGSLTVIQGDTASGKSTLVKALLRVA 673
                  6889**********************9998865 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.0023
                   HHHS-EBTT-EEEEEESTTSSHHHHHHHHHHHSST CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab    6 DalfpivqGqrtlipgafgvGktvisqslskqsns 40  
                   D  f +  Gq+++i g  g Gk+ ++++lsk  ++
   EEA19314.1 1249 DITFDVEAGQKIGICGRTGSGKSSMLSALSKILQT 1283
                   67788999******************999997654 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.1      0.14   1.1e+02      18      39 ..     651     672 ..     638     681 .. 0.82
   2 ?    9.8   0.0   0.00057      0.43      21      60 ..    1262    1301 ..    1247    1308 .. 0.90

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.14
  Zeta_toxin  18 lillgGqpGAGKselaellkde 39 
                 l ++ G +++GKs+l ++l + 
  EEA19314.1 651 LTVIQGDTASGKSTLVKALLRV 672
                 67889***********998765 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00057
  Zeta_toxin   21 lgGqpGAGKselaellkdelerqgnvvrldpDdlRelhPe 60  
                  + G +G+GKs+++++l + l++ ++ +++d+ dl+   P+
  EEA19314.1 1262 ICGRTGSGKSSMLSALSKILQTSRGSITVDGLDLKWISPD 1301
                  7899**************************9999887776 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0      0.16   1.2e+02       2      20 ..     653     671 ..     652     699 .. 0.84
   2 ?    0.9   0.0      0.77   5.7e+02      47      65 ..     762     780 ..     758     793 .. 0.77
   3 ?    6.8   0.1     0.012       8.9       3      25 ..    1262    1284 ..    1260    1300 .. 0.80

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.16
  RNA_helicase   2 wlyGpsgeGKStlakeLak 20 
                   +++G++  GKStl+k L +
    EEA19314.1 653 VIQGDTASGKSTLVKALLR 671
                   689************9876 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.77
  RNA_helicase  47 YtgqevvvidDfgqvkdee 65 
                   Y+++ v+++dD+ +  d +
    EEA19314.1 762 YSRHRVMIFDDIFSALDPA 780
                   99**********9988765 PP

  == domain 3  score: 6.8 bits;  conditional E-value: 0.012
  RNA_helicase    3 lyGpsgeGKStlakeLakallkk 25  
                    ++G++g GKS++   L+k l+++
    EEA19314.1 1262 ICGRTGSGKSSMLSALSKILQTS 1284
                    89*************88887754 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.1     0.043        32      16      41 ..     647     673 ..     640     690 .. 0.78
   2 ?    7.1   0.0    0.0055       4.1      23      49 ..    1262    1288 ..    1254    1309 .. 0.82

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.043
      AAA_30  16 sgdrvavltGpAGtGKttalkal.rea 41 
                 ++  ++v++G   +GK+t++kal r a
  EEA19314.1 647 NQGSLTVIQGDTASGKSTLVKALlRVA 673
                 55579*****************94433 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0055
      AAA_30   23 ltGpAGtGKttalkalreaweaaggrv 49  
                  + G+ G+GK+ +l+al ++++++ g++
  EEA19314.1 1262 ICGRTGSGKSSMLSALSKILQTSRGSI 1288
                  679****************99994333 PP

>> ABC_ATPase  Predicted ATPase of the ABC class
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.1   0.00033      0.25     241     264 ..     645     669 ..     640     674 .. 0.91
   2 ?   -0.8   0.1      0.69   5.2e+02     355     412 ..     767     823 ..     763     841 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00033
                 EE-SS.EEEEEE-TTSSHHHHHHHH CS
  ABC_ATPase 241 gipkG.vtlIvGggfhGKsTLLeAl 264
                  i +G +t+I G  + GKsTL++Al
  EEA19314.1 645 TINQGsLTVIQGDTASGKSTLVKAL 669
                 589999******************9 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.69
                 HH---HHHHHHS-GGG--B--HHHCHHHHHHHH--EEEEEESS-GCCTTT-SEEEEEE CS
  ABC_ATPase 355 lmirDermqelvskekepitplvdrvrelykklgvstilvvggsgdyldvAdtvilme 412
                  mi D+  ++l + + ++i + +   + l ++l  s+i+v+     + ++A+ +++++
  EEA19314.1 767 VMIFDDIFSALDPATMNTIMTKLFAQNGLFRRLKTSVIIVS-NNASLAQLANSILKIN 823
                 6999999************9999999999999999987765.5667888888888776 PP

>> MeaB  Methylmalonyl Co-A mutase-associated GTPase MeaB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       1.4     1e+03      34      50 ..     654     670 ..     629     679 .. 0.76
   2 ?   10.3   0.0   0.00032      0.24      14      55 ..    1242    1283 ..    1234    1294 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 1.4
                 EEE-TTSSHHHHHHHHH CS
        MeaB  34 ltGvPGaGkstlvealg 50 
                 + G   +Gkstlv+al 
  EEA19314.1 654 IQGDTASGKSTLVKALL 670
                 5677789******9985 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00032
                  HHHHHHHHHGGG-S-SEEEEEEE-TTSSHHHHHHHHHHHHHC CS
        MeaB   14 eakellerllakaGraqvvGltGvPGaGkstlvealglelrr 55  
                   a ++le ++ +    q++G+ G  G+Gks +++al   l+ 
  EEA19314.1 1242 GAIDVLEDITFDVEAGQKIGICGRTGSGKSSMLSALSKILQT 1283
                  5678899999999999********************998865 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0     0.067        50      29      55 ..     645     671 ..     638     684 .. 0.86
   2 ?    5.4   0.1     0.016        12      31      59 ..    1255    1283 ..    1250    1290 .. 0.83

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.067
       AAA_7  29 llknkkpvllvGptGtGKtviikdllk 55 
                  ++++  +++ G+t +GK++++k ll+
  EEA19314.1 645 TINQGSLTVIQGDTASGKSTLVKALLR 671
                 5677888999*************9886 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.016
       AAA_7   31 knkkpvllvGptGtGKtviikdllkkldk 59  
                  ++++++ ++G tG+GK+++++ l k l++
  EEA19314.1 1255 EAGQKIGICGRTGSGKSSMLSALSKILQT 1283
                  67888999************999887774 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1461 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       879  (0.0490267); expected 358.6 (0.02)
Passed bias filter:                      508  (0.028334); expected 358.6 (0.02)
Passed Vit filter:                        85  (0.00474092); expected 17.9 (0.001)
Passed Fwd filter:                        25  (0.00139439); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              24  [number of targets reported over threshold]
# CPU time: 1.11u 0.30s 00:00:01.41 Elapsed: 00:00:00.51
# Mc/sec: 8668.27
//
Query:       EEA19315.1  [L=186]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-08   34.3   0.0    2.2e-08   33.7   0.0    1.3  1  Cupin_2   Cupin domain


Domain annotation for each model (and alignments):
>> Cupin_2  Cupin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.7   0.0   1.2e-12   2.2e-08       2      70 ..      90     157 ..      89     158 .. 0.90

  Alignments for each domain:
  == domain 1  score: 33.7 bits;  conditional E-value: 1.2e-12
                 EEEEETTEEEEEECSSSEEEEEEEEESEEEEE.ECTEEEEEETTEEEEE-TT-EEEEEE-SSS-EEEEEE CS
     Cupin_2   2 lvelppGesapshrHpgedeffyVleGegelt.vdgeeveleaGdsvyfpagtpHrfrNtgdeparllvv 70 
                 +v +pp++ +  hr      f++  eGe++ +  dg +++++aGd+  + +gt H++ N +d+par++++
  EEA19315.1  90 VVDFPPNTATIYHRTVSL-DFGILHEGEITCHlDDGVRIDMKAGDV-CVQRGTIHGWTNYTDKPARVYFI 157
                 688999999999997777.*************77799********6.689****************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (186 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       256  (0.0142785); expected 358.6 (0.02)
Passed bias filter:                      248  (0.0138323); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.45
# Mc/sec: 1237.25
//
Query:       EEA19316.1  [L=528]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.7e-41  140.6  38.2    5.7e-41  140.6  38.2    1.4  1  MFS_1     Major Facilitator Superfamily
    3.3e-13   49.3   8.5    3.3e-13   49.3   8.5    1.6  1  Sugar_tr  Sugar (and other) transporter
  ------ inclusion threshold ------
       0.03   12.6   9.8       0.21    9.9   3.8    2.6  2  OATP      Organic Anion Transporter Polypeptide (OATP) family
       0.99    8.6   7.1      0.064   12.5   1.8    1.7  2  TMPIT     TMPIT-like protein


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.6  38.2   1.3e-44   5.7e-41       2     351 ..      91     477 ..      90     479 .. 0.84

  Alignments for each domain:
  == domain 1  score: 140.6 bits;  conditional E-value: 1.3e-44
       MFS_1   2 llaaflsalarsilgpalplalaedlg.ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlga 99 
                 + ++fls l ++i +p ++ ++  +++ +s   ++l+++++ lg+a++ l++++ls+ +Gr  vl ++  l+ l+ + +++a+++  l+++r+l+G+g+
  EEA19316.1  91 AAITFLSPLISTISAPGVS-YMDAEFHnSSSILASLAVSIFVLGFAAGPLIISPLSEIYGRQIVLNICNSLLTLWQIGCALAPNIGSLIAFRFLAGAGG 188
                 6789***************.9*99999455555999***************************************77777779999************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 +a +++g+ +i+d+f+ ++rg+a + ++ g+ +G+i+gp++gg++a+ +gWr++++++  ++ ++ v + ++l +e ++    + k+ +          
  EEA19316.1 189 SACLSIGGGIISDLFTTQQRGLAASAYTFGALFGPIIGPMIGGFIAQRAGWRWAYWVALCAAGVVSV-GNIFLSAETSPTILLRRKTNRlrkeltrpel 286
                 *****************************************************************99.3466666666666666666666777777778 PP

       MFS_1 189 .......kgtgpaplvp.......awkallkdpvlw.illialllfffgfsglltllplylqevlgls....glllaglllallalvgailallagrls 268
                        +gt  ++++        ++++l+  p l+ +  +++++f++ + +++tl+ ly   ++++     gl ++g  l+l+++ g+i    +++ s
  EEA19316.1 287 qsvldakSGTDTSSILVlrrgmirPLRMLFLTPILLcLSTYVAFVFGLLYLLFTTLTSLY-INTYHWQpelcGLAYLG--LGLGCMTGIIT---VAKTS 379
                 887777733344443336666666899999999887778888888887777788888889.***********999999..99999999766...77777 PP

       MFS_1 269 dr............lgrrrrlllallllllaalglallavtssavllllvlvl....iGfglgfvfpsllalasdlappeeagtasglfntagslggal 351
                 d             + ++ rl   +l++l++ +++++ +++ +++++++v +l    +Gfg+  + ++++++  d+ + + a++a++  + +++l g l
  EEA19316.1 380 DAtiirltkanngvYEPEMRLASCVLFALFVPISFFWYGWSADYAVHWIVPILglipFGFGMMGILIPVQTYFIDVGG-HFAASALSGLTAFRCLFGGL 477
                 77777788899999999*******************************966666655777666668999999999887.66666666666666655544 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.3   8.5   7.3e-17   3.3e-13      39     274 ..     114     331 ..      88     339 .. 0.79

  Alignments for each domain:
  == domain 1  score: 49.3 bits;  conditional E-value: 7.3e-17
                 HHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHH CS
    Sugar_tr  39 sskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRg 137
                 + +++ss+l +l vsif++G ++G l++++l++++GR+ +l i++ l+   ++ +a+a+   ++  li+ R+l+G g  ++  +    is + +++ Rg
  EEA19316.1 114 EFHNSSSILASLAVSIFVLGFAAGPLIISPLSEIYGRQIVLNICNSLLTLWQIGCALAP---NIGSLIAFRFLAGAGGSACLSIGGGIISDLFTTQQRG 209
                 34556999***************************************************...************************************* PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS..---HHHHHHTT-HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH CS
    Sugar_tr 138 alvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllfl..PESPrylvekgkeeeakevlaklrgeedadrelaeekdsleae 234
                    s y ++  fG +++ ++g ++++  +   wr+  +++l  a +++++ +fl  + SP  l+ ++     +  l+k    e+  +el+   d+   +
  EEA19316.1 210 LAASAYTFGALFGPIIGPMIGGFIAQRAG---WRWAYWVALCAAGVVSVGNIFLsaETSPTILLRRK-----TNRLRK----ELTRPELQSVLDAKSGT 296
                 *9999999999999999999988877766...99999999999999999998872244555555544.....333333....34444444444444444 PP

                 HH.....HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHH CS
    Sugar_tr 235 qeeekaswkellssktvrqrlligvvlqifqqltGinaim 274
                      +s + l+ ++++ ++l + +++ i+ +l+++ a+ 
  EEA19316.1 297 ----DTS-SILVLRRGMIRPLRMLFLTPILLCLSTYVAFV 331
                 ....222.34555558999999999999999999987765 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.3    0.0011       5.1     142     195 ..      96     148 ..      67     156 .. 0.73
   2 ?    9.9   3.8   4.6e-05      0.21     139     304 ..     181     329 ..     168     374 .. 0.65

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0011
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 142 lGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllkly 195
                 l    ++i + G+sY+d   ++ +s+++ +++ ++ +lG a G l+ s l ++y
  EEA19316.1  96 LSPLISTISAPGVSYMDAEFHN-SSSILASLAVSIFVLGFAAGPLIISPLSEIY 148
                 33334456777*****999875.6789999999999999999988888777777 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 4.6e-05
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 139 qlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllklyvdidseisltpkdprWvgaWWlgflilgvllllaaiplffFP 237
                  +l+G+G+++  ++G   i D  ++++  l  +++++ +++Gp++G ++G+++++                 W  a+W+    +gv+ +   ++ +   
  EEA19316.1 181 RFLAGAGGSACLSIGGGIISDLFTTQQRGLAASAYTFGALFGPIIGPMIGGFIAQ--------------RAGWRWAYWVALCAAGVVSVGNIFLSAETS 265
                 79*************************************************9887..............356888888877777776655544333222 PP

                 xx.xxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 238 ke.lpkkkeerakkkseeesae.kkeekkkkeksksseeeelkslkdfpkalkrllknpifllvilssv 304
                  + l ++k++r + k+ ++  e ++  ++k+ +++s   + l   + +++ l++l+  pi+l++++  +
  EEA19316.1 266 PTiLLRRKTNRLR-KELTRP-ElQSVLDAKSGTDTS---SILVLRRGMIRPLRMLFLTPILLCLSTYVA 329
                 2222222222211.111111.111111111111111...234555667777777777777777655444 PP

>> TMPIT  TMPIT-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   1.8   1.4e-05     0.064     260     317 ..     314     376 ..     304     380 .. 0.74
   2 ?   -2.9   0.3      0.71   3.2e+03     271     301 ..     404     435 ..     400     444 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.4e-05
       TMPIT 260 ltfLlpfLfigqffqlyna...ltlfklall..eeckewqvlvlgllflilalGNflttlkvv 317
                 + fL p+L+++  + +++    ++lf++ ++   ++ +wq  ++gl +l l lG ++ ++ v 
  EEA19316.1 314 MLFLTPILLCLSTYVAFVFgllYLLFTTLTSlyINTYHWQPELCGLAYLGLGLGCMTGIITVA 376
                 78*********99998875121444443322114555*****************999888775 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.71
       TMPIT 271 qffqlynaltlfklall.eeckewqvlvlgll 301
                  +f l++ +++f +  + +   +w v++lgl+
  EEA19316.1 404 VLFALFVPISFFWYGWSaDYAVHWIVPILGLI 435
                 57888888888888777355569999999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (528 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       668  (0.0372581); expected 358.6 (0.02)
Passed bias filter:                      345  (0.0192426); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.61u 0.25s 00:00:00.86 Elapsed: 00:00:00.42
# Mc/sec: 3755.60
//
Query:       EEA19317.1  [L=420]
Description: monocarboxylate permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.2e-24   85.1  50.8    1.3e-23   83.6  48.8    1.9  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.6  48.8     7e-28   1.3e-23       3     352 ..      35     376 ..      33     377 .. 0.86
   2 !   13.8  12.9   1.1e-06      0.02      69     164 ..     303     406 ..     300     419 .. 0.74

  Alignments for each domain:
  == domain 1  score: 83.6 bits;  conditional E-value: 7e-28
       MFS_1   3 laaflsalarsilgpalplalaedlg......ispseigllltlyalgaavaslplGrlsdrfGrrr.vlllglllfalglllllfasslw.lllvlrv 93 
                 ++afl+++a + l++a+   + + +          ++i+++ tl  +  +++ +++G++ dr G  r +l++g  +++lg+++l++a+ ++ +ll+  v
  EEA19317.1  35 VGAFLVYTATWGLLSAYG-SYEKYYEttlmssTPSTTISWVGTLQVVIVILGGIITGPIFDR-GYIReLLFIGTMTTVLGVMMLSLAHEYYqILLAQGV 131
                 689999999999999998.665665556666566677*************************.77777************555558899999******* PP

       MFS_1  94 lqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeeekgtg 192
                   G+g+++l+  +++l+a  f + +r++a+ ++++g+++G i+ p++ + l   +g++++  +l++v+l  +++    +    p+ k++++  +     
  EEA19317.1 132 CIGVGSATLYVPSVSLVASRFQR-RRPLAMFFVTSGTAIGGIIYPIIFSTLQPKIGFSWATRVLGFVTLAELII---AMAIMIPRTKKSKGLHQ----I 222
                 **********************9.***********************************************994...44444455555555555....5 PP

       MFS_1 193 paplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalgl 291
                 ++ l p     ++dp ++++ +a++l+++ ++  ++llp+++ +  g s   +a ++l ++ + +++++ la  +s+r+g+  +l++++++++ + +++
  EEA19317.1 223 RSILDP---TAFHDPAFMAFCLAIFLMWVSYWVPFFLLPTFALFKVGAS-SNIAFYVLVICNASTIPGRYLAVPISNRFGP--ALTMGGFAMASSIILF 315
                 556666...777777776566666666779999****************.68999999**********************9..9999999999999999 PP

       MFS_1 292 allavtssavllllvlvliGfglgfvfpsllalasdlapp.eeagtasglfntagslggalg 352
                  +++v  s + +++  +li +++g   +++  ++ ++ p+ e  gt +g+ + a ++g+++g
  EEA19317.1 316 GWVGVE-SVTSTIIWAILIALFMGPLGALYPIIVPHVSPKkELVGTRIGISSAAAAFGTLVG 376
                 999999.556666667778999****************876999**************9998 PP

  == domain 2  score: 13.8 bits;  conditional E-value: 1.1e-06
       MFS_1  69 lllfalg.lllll.fa..sslwlllvlrvlqGlgagalfpagaaliadwfpk.eergraigllsagfslGailgpllgglla.sslg..Wravfyilai 159
                 + +fa + +++l+ ++   s++  ++  +l +l++g l ++  +++ +++pk e  g  ig+ sa++++G+++g ++ ++l   + g  W +  +    
  EEA19317.1 303 MGGFAMAsSIILFgWVgvESVTSTIIWAILIALFMGPLGALYPIIVPHVSPKkELVGTRIGISSAAAAFGTLVGFPITSALNdIQTGtfWKSEVLNGSC 401
                 5555555334444565667777899***************************8899*************************955555775554333333 PP

       MFS_1 160 vslla 164
                 +++ a
  EEA19317.1 402 MFCGA 406
                 33333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (420 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       885  (0.0493614); expected 358.6 (0.02)
Passed bias filter:                      382  (0.0213063); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 2805.67
//
Query:       EEA19318.1  [L=314]
Description: monocarboxylate permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-17   63.5  41.4      6e-17   61.6  39.3    1.9  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.6  39.3   3.3e-21     6e-17      72     352 ..       3     270 ..       1     271 [. 0.86
   2 !   13.0  10.2     2e-06     0.035      78     164 ..     207     300 ..     202     313 .. 0.74

  Alignments for each domain:
  == domain 1  score: 61.6 bits;  conditional E-value: 3.3e-21
       MFS_1  72 falglllllfasslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfl 169
                 ++lg+++l++a+ ++ +ll+  v  G+g+++l+  +++l+a  f + +r++a+ ++++g+++G i+ p++ + l   +g++++  +l++v+l  +++  
  EEA19318.1   3 TVLGVMMLSLAHEYYqILLAQGVCIGVGSATLYVPSVSLVASRFQR-RRPLAMFFVTSGTAIGGIIYPIIFSTLQPKIGFSWATRVLGFVTLAELII-- 98 
                 6777444447799999*****************************9.***********************************************994.. PP

       MFS_1 170 lllpeepperkrkspkeeekgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrls 268
                   +    p+ k++++  +     ++ l p     ++dp ++++ +a++l+++ ++  ++llp+++ +  g s   +a ++l ++ + +++++ la  +s
  EEA19318.1  99 -AMAIMIPRTKKSKGLHQ----IRSILDP---TAFHDPAFMAFCLAIFLMWVSYWVPFFLLPTFALFKVGAS-SNIAFYVLVICNASTIPGRYLAVPIS 188
                 .44444455555555555....5556666...777777776566666666779999****************.68999999****************** PP

       MFS_1 269 drlgrrrrlllallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdlapp.eeagtasglfntagslggalg 352
                 +r+g+  +l++++++++ + +++ +++v  s + +++  +li +++g   +++  ++ ++ p+ e  gt +g+ + a ++g+++g
  EEA19318.1 189 NRFGP--ALTMGGFAMASSIILFGWVGVE-SVTSTIIWAILIALFMGPLGALYPIIVPHVSPKkELVGTRIGISSAAAAFGTLVG 270
                 ****9..9999999999999999999999.556666667778999****************876999**************9998 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 2e-06
       MFS_1  78 lll.fa..sslwlllvlrvlqGlgagalfpagaaliadwfpk.eergraigllsagfslGailgpllgglla.sslg..Wravfyilaivslla 164
                 +l+ ++   s++  ++  +l +l++g l ++  +++ +++pk e  g  ig+ sa++++G+++g ++ ++l   + g  W +  +    +++ a
  EEA19318.1 207 ILFgWVgvESVTSTIIWAILIALFMGPLGALYPIIVPHVSPKkELVGTRIGISSAAAAFGTLVGFPITSALNdIQTGtfWKSEVLNGSCMFCGA 300
                 333343447777899999************************8899*************************95555577555433333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (314 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       726  (0.0404931); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2178.19
//
Query:       EEA19319.1  [L=314]
Description: monocarboxylate permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-17   63.5  41.4      6e-17   61.6  39.3    1.9  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.6  39.3   3.3e-21     6e-17      72     352 ..       3     270 ..       1     271 [. 0.86
   2 !   13.0  10.2     2e-06     0.035      78     164 ..     207     300 ..     202     313 .. 0.74

  Alignments for each domain:
  == domain 1  score: 61.6 bits;  conditional E-value: 3.3e-21
       MFS_1  72 falglllllfasslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfl 169
                 ++lg+++l++a+ ++ +ll+  v  G+g+++l+  +++l+a  f + +r++a+ ++++g+++G i+ p++ + l   +g++++  +l++v+l  +++  
  EEA19319.1   3 TVLGVMMLSLAHEYYqILLAQGVCIGVGSATLYVPSVSLVASRFQR-RRPLAMFFVTSGTAIGGIIYPIIFSTLQPKIGFSWATRVLGFVTLAELII-- 98 
                 6777444447799999*****************************9.***********************************************994.. PP

       MFS_1 170 lllpeepperkrkspkeeekgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrls 268
                   +    p+ k++++  +     ++ l p     ++dp ++++ +a++l+++ ++  ++llp+++ +  g s   +a ++l ++ + +++++ la  +s
  EEA19319.1  99 -AMAIMIPRTKKSKGLHQ----IRSILDP---TAFHDPAFMAFCLAIFLMWVSYWVPFFLLPTFALFKVGAS-SNIAFYVLVICNASTIPGRYLAVPIS 188
                 .44444455555555555....5556666...777777776566666666779999****************.68999999****************** PP

       MFS_1 269 drlgrrrrlllallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdlapp.eeagtasglfntagslggalg 352
                 +r+g+  +l++++++++ + +++ +++v  s + +++  +li +++g   +++  ++ ++ p+ e  gt +g+ + a ++g+++g
  EEA19319.1 189 NRFGP--ALTMGGFAMASSIILFGWVGVE-SVTSTIIWAILIALFMGPLGALYPIIVPHVSPKkELVGTRIGISSAAAAFGTLVG 270
                 ****9..9999999999999999999999.556666667778999****************876999**************9998 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 2e-06
       MFS_1  78 lll.fa..sslwlllvlrvlqGlgagalfpagaaliadwfpk.eergraigllsagfslGailgpllgglla.sslg..Wravfyilaivslla 164
                 +l+ ++   s++  ++  +l +l++g l ++  +++ +++pk e  g  ig+ sa++++G+++g ++ ++l   + g  W +  +    +++ a
  EEA19319.1 207 ILFgWVgvESVTSTIIWAILIALFMGPLGALYPIIVPHVSPKkELVGTRIGISSAAAAFGTLVGFPITSALNdIQTGtfWKSEVLNGSCMFCGA 300
                 333343447777899999************************8899*************************95555577555433333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (314 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       726  (0.0404931); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.33s 00:00:00.90 Elapsed: 00:00:00.53
# Mc/sec: 1797.93
//
Query:       EEA19320.1  [L=525]
Description: MFS quinate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   3.1e-111  372.5  19.2   3.5e-111  372.3  19.2    1.0  1  Sugar_tr  Sugar (and other) transporter
    8.5e-23   80.8  32.3    9.2e-18   64.3   3.9    2.0  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  372.3  19.2  3.9e-115  3.5e-111       2     452 .]      32     498 ..      31     498 .. 0.94

  Alignments for each domain:
  == domain 1  score: 372.3 bits;  conditional E-value: 3.9e-115
                 HHHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTS CS
    Sugar_tr   2 alvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgkn 100
                 a  a++gg+lfg dtg+i+++ltl++f  +fgls+ +s     + ls  +v  +++Gai+G+l a ++++++GRkkslli+av+++ig + q +a    
  EEA19320.1  32 AAAACFGGTLFGMDTGIISGVLTLPDFKQEFGLSNLDSVAR--ANLSANLVTTVQAGAIAGALGALPFAEKLGRKKSLLIVAVVAFIGPLFQTFAY--G 126
                 6789*******************************998555..699**************************************************..7 PP

                 S-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHH.HTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHH CS
    Sugar_tr 101 svevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglgl.nktsnadgwrillglqlvpallllilllflPESPryl 198
                 ++  +++gR++ G+g+G+a++l+P+y+sE+Ap  +Rg l+++yql+ t+G ++a+++++g   ++ ++  w ++l++q++p++l++  +lf+PESPr+l
  EEA19320.1 127 HYAPFYIGRFIEGLGLGGATMLAPTYVSENAPRGIRGLLIGFYQLFETMGAMIAFFIDYGSlLHIPGHASWMVPLAMQALPPILIFGSILFCPESPRWL 225
                 8************************************************************999999******************************** PP

                 HHTT-HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH...........H...TTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-TH CS
    Sugar_tr 199 vekgkeeeakevlaklrgeedadrelaeekdsleaeqeee......kasw...kellssktvrqrlligvvlqifqqltGinaimyysptifenlglsk 288
                  ++++ ee+++vl k+r  + +++++++e  +l+ + eee      + +w   ke +   ++r r+li ++l+++qq tG nai yy+ptif +lg++ 
  EEA19320.1 226 ASQDNWEETTKVLVKVRHLPSDHPYIQQELLELRTALEEErrsaggNGFWalqKECWLIPGNRNRALISIGLMVCQQWTGTNAINYYAPTIFTSLGITG 324
                 *****************************99999999988997888666622245555556************************************99 PP

                 H...HHHHHHHHHHHHHHHHHHH.HHHHHS-SHHHHHHHHHHHHHHHHHHH...HHHHTTSS......CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHS CS
    Sugar_tr 289 s...llvtiivgvvnfvatfvai.flvdrfGRRtllllGaagmaicfvilg.ivalllvaks...kaasivaivfialfialfalgwgpvpwvlvsElf 379
                 +   ll+t+++g+v++v++ + i fl d +GRR  l++ a+ m i++++lg +v +  +++    ++a+++a+v++++f+a+f++gwgpv+w++vsE+ 
  EEA19320.1 325 EsnsLLATGVYGIVKMVSCGIFItFLADSLGRRWSLVWTAFAMWIFMFYLGfYVRFDAPEAGaaiSSAGYAALVMVYFFAAAFQFGWGPVCWIYVSEIP 423
                 9999***************99966***************************8666666666679*********************************** PP

                 HTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH...T-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 380 pqsvRskalaiavavnwlanflisllfpiiteaig...ggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 ++++R++  ++a+a++wl+n+++s ++p+++ ++g   g+++++++++++  ++    ff+petkg +le ++elf
  EEA19320.1 424 SNRLRGLNVSLAAASQWLFNLVVSRVTPVMLVTVGgktGYGTYFIYGSFCF-TMGCLAFFLPETKGISLERMDELF 498
                 **********************************99999999999999875.55667889*************997 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.3   3.9     1e-21   9.2e-18       2     198 ..      36     240 ..      35     268 .. 0.78
   2 !   22.6  20.5     5e-09   4.5e-05       3     176 ..     297     486 ..     295     516 .. 0.83

  Alignments for each domain:
  == domain 1  score: 64.3 bits;  conditional E-value: 1e-21
       MFS_1   2 llaaflsalarsilgpalpl.alaedlgispse....igl...lltlyalgaavaslplGrlsdrfGrrr.vlllglllfalglllllfasslw.lllv 90 
                 ++++ l +++ +i++ +l+l   ++++g+s       ++l   l+t++ +ga++++l + ++++++Gr++ +l++++++f+   l+ +fa +++ ++++
  EEA19320.1  36 CFGGTLFGMDTGIISGVLTLpDFKQEFGLSNLDsvarANLsanLVTTVQAGAIAGALGALPFAEKLGRKKsLLIVAVVAFIGP-LFQTFAYGHYaPFYI 133
                 78999***********************6666666664445569999999********************5555555555555.555578777779*** PP

       MFS_1  91 lrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllgglla.sslg...Wravfyilaivsllafv.lfllllpeepperkrksp 184
                 +r++ Glg g+++ ++ +++++ +p+  rg+ ig+++++  +Ga+++  +    + +  g   W ++  + a+  +l f  +  l+ pe+p+  + +  
  EEA19320.1 134 GRFIEGLGLGGATMLAPTYVSENAPRGIRGLLIGFYQLFETMGAMIAFFIDYGSLlHIPGhasWMVPLAMQALPPILIFGsI--LFCPESPRWLASQDN 230
                 ***********************************************99987444244446667777777776666664422..555666666666666 PP

       MFS_1 185 keeekgtgpaplvp 198
                 +ee      + lv+
  EEA19320.1 231 WEE----TTKVLVK 240
                 666....4444444 PP

  == domain 2  score: 22.6 bits;  conditional E-value: 5e-09
       MFS_1   3 laaflsalarsilgpalplalaedlgispseigllltl.yalga.avaslplGrlsdrfGrrr.vlllglllfalglllllf.........a....ssl 85 
                 l+++   ++ ++++  +p ++ ++lgi++ + +ll+t+ y+++  +   +++ +l+d +Grr+ ++++++++++++++l+++         a    +++
  EEA19320.1 297 LMVCQQWTGTNAINYYAP-TIFTSLGITGESNSLLATGvYGIVKmVSCGIFITFLADSLGRRWsLVWTAFAMWIFMFYLGFYvrfdapeagAaissAGY 394
                 677888899999999999.9**************999867776656778888***********999999999999955555355587665416666778 PP

       MFS_1  86 wlllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg...Wravfyilaivsllafvlfllllpeep 176
                  +l+ + +++++++ +  p++ ++++++ + + rg+ ++l++a+  l  ++   + ++++  +g     ++++i + +++ ++ l  ++++ e 
  EEA19320.1 395 AALVMVYFFAAAFQFGWGPVCWIYVSEIPSNRLRGLNVSLAAASQWLFNLVVSRVTPVMLVTVGgktGYGTYFIYGSFCFTMGCL--AFFLPET 486
                 89************9999*******************************9999999988855554999999*********99885..3433333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (525 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       695  (0.038764); expected 358.6 (0.02)
Passed bias filter:                      384  (0.0214178); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.27s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 3359.37
//
Query:       EEA19321.1  [L=532]
Description: MFS quinate transporter QutD [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.5e-121  406.5  31.8   1.7e-121  406.3  31.8    1.0  1  Sugar_tr       Sugar (and other) transporter
    1.6e-27   96.4  69.8    2.9e-24   85.6  38.6    2.1  2  MFS_1          Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  406.3  31.8  1.9e-125  1.7e-121       2     452 .]      28     489 ..      27     489 .. 0.94

  Alignments for each domain:
  == domain 1  score: 406.3 bits;  conditional E-value: 1.9e-125
                 HHHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTS CS
    Sugar_tr   2 alvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgkn 100
                 a+ a+ ++ ++gYd+++ig++l+l++f++ fgl+ +++     ++ls+ ivs f++Ga++G++++ +l++rfGRk ++++++++f++g ++q + +   
  EEA19321.1  28 AFSATWASAMYGYDSAFIGGTLSLPSFQTSFGLTPATA-----TSLSSNIVSTFQAGAFFGAILGFFLAERFGRKLVIIFFGLIFIVGVIIQLIGH--- 118
                 7889999****************************997.....3578***********************************************99... PP

                 S-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHH.HTSS-..TTHHHHHHHCCHHHHHHHHHHGGGS---HH CS
    Sugar_tr 101 svevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglgl.nktsn..adgwrillglqlvpallllilllflPESPr 196
                  + +l++gR l+G+ +G++s+++P+yisE +p+++Rg++v++++ ++++  ++++++++g+ +++s+  +++wri++g+ql+p  llli++ f+ ESPr
  EEA19321.1 119 -LGMLYAGRALTGLTIGCTSMIIPIYISECSPAQIRGRMVGMFEIMLQIALVFGFWVNYGVqKNISGsdTKQWRIPVGVQLIPVGLLLIFMPFMIESPR 216
                 .************************************************************88888799****************************** PP

                 HHHHTT-HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH...........HTTHHHHSH......HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS- CS
    Sugar_tr 197 ylvekgkeeeakevlaklrgeedadrelaeekdsleaeqeee......kaswkellsskt...vrqrlligvvlqifqqltGinaimyysptifenlgl 286
                 +lv+k + e+a + la++r+ ++++++l  e++ ++a++e e      +    ++l++++   +r r++i v+l+++q+ltGinai yysptif+++g+
  EEA19321.1 217 WLVSKSRNERALKNLAWVRNLPEDHPYLLREMADIQAGVEHElqlvngSRGAFQMLRECGtpgIRNRIIISVMLMLLQNLTGINAINYYSPTIFKSIGF 315
                 ****************************************99999976333444455555688************************************ PP

                 THH...HHHHHHHHHHHHHHHHHH.HHHHHHS-SHHHHHHHHHHHHHHHHHHH...HHHHTTSS..........CHHHHHHHHHHHHHHHTTTTHHHHH CS
    Sugar_tr 287 sks...llvtiivgvvnfvatfva.iflvdrfGRRtllllGaagmaicfvilg.ivalllvaks.......kaasivaivfialfialfalgwgpvpwv 373
                 + +   ll+t+++g v++++t+v  +f+vd+fGRR+ ll+Ga+g+a+++++lg +      ++s       ++ s++a+++i++++++++++w+++pw+
  EEA19321.1 316 TGTsvqLLATGVYGLVKMATTVVFmVFIVDKFGRRPALLVGAVGAAVAMFYLGiY---SELSGSfhkippkDSGSNAAVAMIYIYAIFYGFSWNGIPWI 411
                 *999******************9978***************************52...22222234577879*************************** PP

                 HHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 374 lvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 ++sE+ p++vR+++++++v+++wla+f + +  p ++++i+ +++f++f+++ ++++ f ++fvpetkg++lee++ lf
  EEA19321.1 412 IASEILPNRVRTLGMMFSVCMQWLAQFMVVYSLPHMVKTIT-FGIFYFFGACTLVALAFAWLFVPETKGVPLEEMDFLF 489
                 *****************************************.*********************************9765 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.6  38.6   3.3e-28   2.9e-24       4     348 ..      34     436 ..      25     441 .. 0.83
   2 !   25.0  23.2   9.3e-10   8.3e-06       2     178 ..     289     478 ..     288     488 .. 0.79

  Alignments for each domain:
  == domain 1  score: 85.6 bits;  conditional E-value: 3.3e-28
       MFS_1   4 aaflsalarsilgpalpl.alaedlgispseigl....lltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqG 96 
                 a ++++++++++g +l+l   ++++g++p+++      +++++ +ga+++++++ +l++rfGr+ v+++  l+f++g +++ + +++  +l+++r+l+G
  EEA19321.1  34 ASAMYGYDSAFIGGTLSLpSFQTSFGLTPATATSlssnIVSTFQAGAFFGAILGFFLAERFGRKLVIIFFGLIFIVG-VIIQL-IGHLgMLYAGRALTG 130
                 56778889999*****999*******9999966667789**************************************.77777.66677********** PP

       MFS_1  97 lgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg......Wravfyilaivsllafvlfllllpeepperkrkspkeee. 188
                 l+ g+   ++ ++i++ +p + rgr++g++ ++ +++ ++g  +   +  +++      Wr +  +  i   l+++ f+ ++ e+p+    ks  e+  
  EEA19321.1 131 LTIGCTSMIIPIYISECSPAQIRGRMVGMFEIMLQIALVFGFWVNYGVQKNISgsdtkqWRIPVGVQLIPVGLLLI-FMPFMIESPRWLVSKSRNERAl 228
                 *************************************************99999************9999999977.4566656666666665555558 PP

       MFS_1 189 ................................kgtgpaplvp.....awkallkdpvlwillialllfffgfsglltllplylqevlgls....gllla 246
                                                    g +++++     +   ++++  + +++++ll + +g++++ +++p++  +  g++      lla
  EEA19321.1 229 knlawvrnlpedhpyllremadiqagvehelqLVNGSRGAFQmlrecGTPGIRNRIII-SVMLMLLQNLTGINAINYYSPTI-FKSIGFTgtsvQ-LLA 324
                 9999999999999999999999888777777733444444442223333333333333.799999999*************7.*******99855.777 PP

       MFS_1 247 glllallalvgailallagrlsdrlgrrrrlllallllllaalglallavt...........ssavllllvlvliGfglgfv.fpsllalasdlappee 333
                 +++++l+ +++ ++  +  +++d++grr++ll++ +++++a + l + +             s + +++++++++ +++gf  +++ + +as+ +p++ 
  EEA19321.1 325 TGVYGLVKMATTVV--FMVFIVDKFGRRPALLVGAVGAAVAMFYLGIYSELsgsfhkippkdSGSNAAVAMIYIYAIFYGFSwNGIPWIIASEILPNRV 421
                 77899999998777..888888**************************999999999999986666666688889998888867777888888888777 PP

       MFS_1 334 agtasglfntagslg 348
                 +   + +   ++ l+
  EEA19321.1 422 RTLGMMFSVCMQWLA 436
                 777766666665555 PP

  == domain 2  score: 25.0 bits;  conditional E-value: 9.3e-10
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltl.yalga.avaslplGrlsdrfGrrrvlllglllfalglllll.f...a..........ss 84 
                 +l+++ + +++++++   p ++ ++ g+++++++ll+t+ y+l+  a +++++ +++d+fGrr+ ll+g+++ a+++++l  +   +          s+
  EEA19321.1 289 MLMLLQNLTGINAINYYSP-TIFKSIGFTGTSVQLLATGvYGLVKmATTVVFMVFIVDKFGRRPALLVGAVGAAVAMFYLGiYselSgsfhkippkdSG 386
                 6777888899999999999.9**************988878887735555555899********************55555464441445455667666 PP

       MFS_1  85 lwlllvlrvlqGlgagalfpagaali.adwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeeppe 178
                 + + +++  + ++++g+++ ++  +i +++ p + r++++ +   +  l+  +     + ++  + + ++fy++++ +l+a+ +  ++l++++++
  EEA19321.1 387 SNAAVAMIYIYAIFYGFSWNGIPWIIaSEILPNRVRTLGMMFSVCMQWLAQFMVVYSLPHMVKTITF-GIFYFFGACTLVALAF--AWLFVPETK 478
                 889******************9866515778888888888777778889998888888999988877.9************666..555555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (532 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       956  (0.0533214); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.47
# Mc/sec: 3400.55
//
Query:       EEA19322.1  [L=268]
Description: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.7e-62  211.0   0.0      2e-62  210.8   0.0    1.0  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    2.8e-46  157.4   0.0    3.4e-46  157.2   0.0    1.1  1  adh_short        short chain dehydrogenase
    9.3e-12   45.2   0.1    1.5e-11   44.6   0.1    1.3  1  KR               KR domain
    2.6e-06   27.1   0.0     0.0001   21.8   0.0    2.2  2  Epimerase        NAD dependent epimerase/dehydratase family
    1.7e-05   24.1   0.0    2.4e-05   23.6   0.0    1.2  1  Polysacc_synt_2  Polysaccharide biosynthesis protein
    5.6e-05   22.7   0.0      8e-05   22.2   0.0    1.2  1  GDP_Man_Dehyd    GDP-mannose 4,6 dehydratase
     0.0023   17.9   0.0     0.0036   17.2   0.0    1.3  1  3HCDH_N          3-hydroxyacyl-CoA dehydrogenase, NAD binding
     0.0069   16.8   0.0      0.012   16.0   0.0    1.3  1  NAD_binding_7    Putative NAD(P)-binding
  ------ inclusion threshold ------
      0.023   14.9   0.0      0.035   14.3   0.0    1.3  1  NAD_binding_2    NAD binding domain of 6-phosphogluconate deh
      0.023   14.5   0.0      0.045   13.6   0.0    1.4  1  Methyltransf_31  Methyltransferase domain
       0.12   12.6   0.0       0.51   10.6   0.0    2.0  2  TrkA_N           TrkA-N domain
       0.14   12.2   0.0       0.22   11.6   0.0    1.3  1  Ldh_1_N          lactate/malate dehydrogenase, NAD binding do
       0.16   11.4   0.0       0.25   10.7   0.0    1.3  1  2-Hacid_dh_C     D-isomer specific 2-hydroxyacid dehydrogenas


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  210.8   0.0   1.4e-65     2e-62       1     233 [.      23     265 ..      23     266 .. 0.95

  Alignments for each domain:
  == domain 1  score: 210.8 bits;  conditional E-value: 1.4e-65
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGH.HHHHHHHHHHTTSE..E......EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GG CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneea.kkrveelaeelgae..v......lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfl 88 
                   Gaa  IG+++A+++ +eGa+v l+d++e a  +++++l+++++ +  +      +++DVtd+ +ve++v+++ve+fg+lD ++ +agi+ + ++++l
    EEA19322.1  23 GAAGNIGFETARRFLAEGAKVSLVDIQETAlSDAIQKLQDAFPDDtsLteriltIRADVTDQPDVERFVAQTVERFGGLDTAFFCAGISYS-STSIL 118
                   99***************************************9955332455589************************************9.***** PP

                   GH-HHHHHHHHHHHTHHHHHHHHHHHHHCTSC...CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGS CS
  adh_short_C2  89 etsreefdraldvnlyslfllakaalplmkeg...gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgi 182
                   +t++e +d++++vn++s+fl +k+a ++m+++   gsi+  ss+++ r++p+  ay+ aK al +l+ ++A+elg+++iRvN+v+p  ++T++ ++ 
    EEA19322.1 119 DTDDELWDKVIKVNTRSAFLGIKYAGRVMRDSgkgGSIILASSIAGLRATPGLCAYSSAKYALRGLCVTAAAELGQHQIRVNTVHPCGVNTPMFQAT 215
                   ***************************99976688**********************************************************9999 PP

                   TTHHHHHHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEESTTG CS
  adh_short_C2 183 kgfdelleelearaplgrlgtpeevaeaalfLasdeasyitGqtlvvDgGl 233
                      +e +++l +  plgr++++e+va++++fLasd+a++ tG  l vDgG+
    EEA19322.1 216 W-PPEKMKQLLSTVPLGRWAEVEDVAALVAFLASDDAQFLTGGALKVDGGI 265
                   8.6777888999**************************************6 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  157.2   0.0   2.5e-49   3.4e-46       1     191 [.      17     216 ..      17     220 .. 0.95

  Alignments for each domain:
  == domain 1  score: 157.2 bits;  conditional E-value: 2.5e-49
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT.......TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---S.S--S CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee.......gakalaiqvDvtdreevealvekavkklgkldvLvnNAGi.tgsg 91 
                 k++l+tGa++ IG ++a+++++eGakv +vd++e +l  ++++l+++        +++l+i++Dvtd+ +ve++v++ v+++g+ld    +AGi   s+
  EEA19322.1  17 KIALITGAAGNIGFETARRFLAEGAKVSLVDIQETALSDAIQKLQDAfpddtslTERILTIRADVTDQPDVERFVAQTVERFGGLDTAFFCAGIsYSST 115
                 79*******************************************998876666677*************************************77788 PP

                 SGGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHH.HCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHH CS
   adh_short  92 pfselseeewervievNltgvflltravlpaml.kqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmake 189
                 ++ ++++e w++vi+vN  ++fl ++ + + m  ++++G+I+  sS+ag+ + +g++aYs++K a++gl  ++a el +++irvn+v+P +v+T+m ++
  EEA19322.1 116 SILDTDDELWDKVIKVNTRSAFLGIKYAGRVMRdSGKGGSIILASSIAGLRATPGLCAYSSAKYALRGLCVTAAAELGQHQIRVNTVHPCGVNTPMFQA 214
                 899999999***********************9999************************************************************998 PP

                 HC CS
   adh_short 190 lr 191
                 + 
  EEA19322.1 215 TW 216
                 75 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.6   0.1   1.1e-14   1.5e-11       4     160 ..      20     185 ..      18     202 .. 0.80

  Alignments for each domain:
  == domain 1  score: 44.6 bits;  conditional E-value: 1.1e-14
                 EEETTTSHHHHHHHHHHHHHHS-.EEEEE-SS..--HHHHHHHHHHHHTT-...EEEE----TT-HHHHHHHHHHHHHHSS---EEEE------.---T CS
          KR   4 litGGlGgLGlelarwlaekgar.hlvllsRsaaadedskaliaelealga...evevvaaDvsdkdavealleeikaeeppikGvihaAgvlr.dkll 97 
                 litG++G++G e+ar  +++ga+ +lv +  + a +++ ++l +++ +      ++ +++aDv+d+ +ve+ +++  ++++ +   + +Ag++   + +
  EEA19322.1  20 LITGAAGNIGFETARRFLAEGAKvSLVDIQET-ALSDAIQKLQDAFPDDTSlteRILTIRADVTDQPDVERFVAQTVERFGGLDTAFFCAGISYsSTSI 117
                 9**************99999966156666555.4444444444444333223449************************************9763789* PP

                 TT--HHHHHHHHTTTTH....HHHHHHHHTTT.S--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHH CS
          KR  98 eemtaedleqvlapKvk....GawnLhelled.esldffvlfSSiagllgsagqanYaaaNaflDala 160
                  ++++e +++v++   +    G++   ++++d  +   ++l SSiagl  ++g ++Y++a   l +l+
  EEA19322.1 118 LDTDDELWDKVIKVNTRsaflGIKYAGRVMRDsGKGGSIILASSIAGLRATPGLCAYSSAKYALRGLC 185
                 ***********97665422227888888998888999***********************98887776 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   0.0   7.5e-08    0.0001       1      63 [.      19      94 ..      19     133 .. 0.76
   2 ?    3.1   0.0     0.039        54     141     192 ..     173     227 ..     167     253 .. 0.74

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 7.5e-08
                EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC..............EEEE--TT-HHHHHHHHHHH CS
   Epimerase  1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl..............elveldltdrsalerlfkee 63
                +l+tGa+G iG  +++++l++g +v  +d +++a   a ++ l                +++d+td+ ++er+++++
  EEA19322.1 19 ALITGAAGNIGFETARRFLAEGAKVSLVDIQETALSDAIQK-LqdafpddtslteriLTIRADVTDQPDVERFVAQT 94
                59**************************9996655544333.3588*********99899*************9974 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.039
                 HHHHHHHHHHHHHHHHHHHHT-EEEEEEESEEESTT..S-TTS.TTSHHHHHHHH CS
   Epimerase 141 pYaaaKlageklveayaaqyglnaiilrlfnlyGpr..ngege.vsrvipalirk 192
                 +Y+ aK+a   l+  +aa+ g + i ++  + +G +   ++ + +  ++ +l++ 
  EEA19322.1 173 AYSSAKYALRGLCVTAAAELGQHQIRVNTVHPCGVNtpMFQATwPPEKMKQLLST 227
                 69******************99999999999999985544444455555555444 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.6   0.0   1.8e-08   2.4e-05       2      75 ..      20      93 ..      19     104 .. 0.87

  Alignments for each domain:
  == domain 1  score: 23.6 bits;  conditional E-value: 1.8e-08
                     EEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH......-.TTEEEE....E--TT-HHHHHHHTT. CS
  Polysacc_synt_2  2 lvtGagGsiGselvrqilkkkpkkiillerdElklyeiekeleeelkk.kklkveivpvigdvrdkerlekalee 75
                     l+tGa+G iG e  r++l++  +k+ l++ +E++l +  ++l++ + + ++l+ +i+++ +dv+d+  +e+ + +
       EEA19322.1 20 LITGAAGNIGFETARRFLAEG-AKVSLVDIQETALSDAIQKLQDAFPDdTSLTERILTIRADVTDQPDVERFVAQ 93
                     8*****************976.579***********999998888865156888899999********9998874 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.2   0.0   5.8e-08     8e-05       1      74 [.      20      94 ..      20      97 .. 0.82

  Alignments for each domain:
  == domain 1  score: 22.2 bits;  conditional E-value: 5.8e-08
                   EEETTTSHHHHHHHHHHHHCT-CCEEEEEEE..SS-TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHHHH CS
  GDP_Man_Dehyd  1 LiTGiaGfiGsylaelLlekgyevhgivrrs..ssfntgriehlakdpkeeleenlklhkgDltDssslerllaev 74
                   LiTG aG iG  +a+++l++g +v  ++ ++   s ++++++    d+ ++l+e++  +++D+tD+  +er +a++
     EEA19322.1 20 LITGAAGNIGFETARRFLAEGAKVSLVDIQEtaLSDAIQKLQDAFPDD-TSLTERILTIRADVTDQPDVERFVAQT 94
                   9**********************9887554401445567777777666.46889*****************99875 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   2.6e-06    0.0036       6      46 ..      23      64 ..      17      94 .. 0.84

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 2.6e-06
                --.SCCHHHHHHHHHHTT-EEEEE-S-HHHHHHHHHHHHHHH CS
     3HCDH_N  6 Ga.GtmGagiaavfasagleVvlvdiseealekalekieksl 46
                Ga G +G + a  f+++g +V lvdi+e al +a +k+++ +
  EEA19322.1 23 GAaGNIGFETARRFLAEGAKVSLVDIQETALSDAIQKLQDAF 64
                544**********************************99865 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   8.7e-06     0.012       5      66 ..      14      75 ..      12     109 .. 0.73

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 8.7e-06
  NAD_binding_7  5 lkgkkvlvvG.gGevAarkvrklleagakvtvvapevkeeleelvklaeeelekdlegadlvi 66
                   lk+k  l+ G +G+++ + +r++l++gakv +v+ + + +l++ ++  ++ +++d + ++ ++
     EEA19322.1 14 LKDKIALITGaAGNIGFETARRFLAEGAKVSLVDIQ-ETALSDAIQKLQDAFPDDTSLTERIL 75
                   788999999945*********************999.56667778888888888855444222 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   2.6e-05     0.035       8      95 ..      26     113 ..      17     123 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2.6e-05
                    SHHHHHHHHHHHHTT-EEEEE-SSHHHHHHHHHTTEEE-SSHHHHHHHCSEEEE-SSSHHHHHHHHHSHCCC--TT-EEEE-S---HH CS
  NAD_binding_2   8 GvMGsnmalnllkagykvavynrtkekveelvaegakaaesieelvasldvvitmvkagkavdeviegllealkkgdilidgstsspe 95 
                    G++G + a+++l++g kv++++ ++ ++ +++++  +a+ +  +l++++ ++   v+++++v+ ++ + +e++   d+   ++ +s++
     EEA19322.1  26 GNIGFETARRFLAEGAKVSLVDIQETALSDAIQKLQDAFPDDTSLTERILTIRADVTDQPDVERFVAQTVERFGGLDTAFFCAGISYS 113
                    99****************************************************************9988887666665555555555 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.0   3.3e-05     0.045      14      55 ..      25      67 ..      21      89 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 3.3e-05
  Methyltransf_31 14 tGeltfelae.elgpkaevvGiDiseeaielArenaqklgldn 55
                     +G+++fe a+  l ++a+v ++Di+e+a++ A +++q+ + d 
       EEA19322.1 25 AGNIGFETARrFLAEGAKVSLVDIQETALSDAIQKLQDAFPDD 67
                     6999*****954556999*****************99988775 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00037      0.51       6      48 ..      25      67 ..      19      85 .. 0.79
   2 ?   -1.2   0.0       1.6   2.3e+03      58      81 ..     234     257 ..     232     264 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00037
                -SHHHHHHHHHHHHTTEEEEEEESSHHHHHHHHHTTSEEEES- CS
      TrkA_N  6 lGrvGrslaeeLseggkdvvvidkdeerveelreeglevvvgd 48
                +G++G + a+++ ++g +v+++d +e ++  + ++  +++  d
  EEA19322.1 25 AGNIGFETARRFLAEGAKVSLVDIQETALSDAIQKLQDAFPDD 67
                7*************6657********99998887776665555 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 1.6
                 TTGGGESEEEE-SSSHHHHHHHHH CS
      TrkA_N  58 agiekadaviaatgddeanilavl 81 
                 a++e++ a++a + +d+a  l+  
  EEA19322.1 234 AEVEDVAALVAFLASDDAQFLTGG 257
                 789999999*99999998877655 PP

>> Ldh_1_N  lactate/malate dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   0.00016      0.22       4      49 ..      20      63 ..      16      86 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00016
                EEETTTSHHHHHHHHHHHHTTSSSEEEEE-SSHHHHHHHHHHHHHC CS
     Ldh_1_N  4 avvGaaGgiGqslalllankkladelaLlDiakekleGvaldlshi 49
                 ++GaaG+iG ++a   ++++   ++ L+Di++ +l+  +  l+++
  EEA19322.1 20 LITGAAGNIGFETARRFLAEGA--KVSLVDIQETALSDAIQKLQDA 63
                478************9999864..479*****99999888888876 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00018      0.25      33      73 ..      13      54 ..       4      85 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00018
                  -GTTSEEEEES.-SHHHHHHHHHHHHTT-EEEEESSSHHHHH CS
  2-Hacid_dh_C 33 elsgktvGiiG.lGrIGqavakrlkafgmkviaydrskkkee 73
                  +l++k   i G +G+IG ++a+r+ a g+kv  +d ++++ +
    EEA19322.1 13 RLKDKIALITGaAGNIGFETARRFLAEGAKVSLVDIQETALS 54
                  6788888888845**********************9977544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (268 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       552  (0.0307881); expected 358.6 (0.02)
Passed bias filter:                      528  (0.0294495); expected 358.6 (0.02)
Passed Vit filter:                        69  (0.00384851); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 1868.72
//
Query:       EEA19323.1  [L=333]
Description: 4-hydroxyphenylpyruvate dioxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.3e-28   99.9   0.0    2.2e-28   99.1   0.0    1.4  2  AP_endonuc_2  Xylose isomerase-like TIM barrel


Domain annotation for each model (and alignments):
>> AP_endonuc_2  Xylose isomerase-like TIM barrel
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.1   0.0   1.2e-32   2.2e-28       3     203 ..      26     266 ..      24     273 .. 0.92
   2 ?   -3.1   0.0      0.24   4.2e+03     102     119 ..     312     329 ..     294     332 .. 0.50

  Alignments for each domain:
  == domain 1  score: 99.1 bits;  conditional E-value: 1.2e-32
                   HHHHCT-SEEEEECCTCSHHHHC......HHHHHHHHHHHHHHTTSEEEEEEECCCHSTCTHCHTTCSHHHHHHHHHHHHHHHHHHTBSEEEEEBCC CS
  AP_endonuc_2   3 aaaeaGfdgvElfgrdlvpvsel......sdeelrelrkaldelglriaslslftrfgypdederearreesvdalkraielaaaLGapllvlhpGt 93 
                   aaa++Gf + E+ + dl  +++        +++++++ ++++++++ i sl++f +f++     +++r    +d ++++ie a+ L a +l+++   
    EEA19323.1  26 AAAHHGFSALEIVYNDLATYAASktpkitIQAAAKDISSLCASHNISILSLNPFKNFEGHSS-PLSER----LDSARHWIEVASLLQAQHLQVP--- 114
                   79******************999************************************555.47777....**********************... PP

                   GBCTTTSGHHHHHHHHHHHHHHHHHHHH..HHTSEEEEE--TTTTSSSTCHHHHHHHHHHTTTTEEEEEEHHHHHHH..............TTTHHH CS
  AP_endonuc_2  94 agagpkgseeeawerlaeslneladyae..kegvklalEtlagsgvelgdeelarlldavdspnvgvclDtgHllia..............eedvdd 174
                    ++ + ++   + + +++ l++lad+a+  + g ++a+E  a+    + +++ +r+++ v++ n+gvclD +H +++              + +vdd
    EEA19323.1 115 -SQFDTENSTGDENVVISELQQLADMAAkiAPGLRIAYEAVAWGSYVDTWQDSLRIVELVNRANFGVCLDSFHVVARlwgdimsesgkqetGQNVDD 210
                   .6789999999*****************66678**************************************************************** PP

                   HHHHHHGG.........EEEEEE.EESS..................TTTTSSTTEE CS
  AP_endonuc_2 175 alraladr.........ikhvHikDakg..................dlgagrdrhv 203
                   alr+  d          i++v+++D+++                   l ++r+ + 
    EEA19323.1 211 ALRQSLDEfglacpldkIFYVQLSDGEKyspplspehrfyeasfpsALTWSRNTRP 266
                   ***************************98877777777777777766666666665 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 0.24
                   HHHHHHHHHHHHHHHHHH CS
  AP_endonuc_2 102 eeeawerlaeslnelady 119
                   ++++ +r +es+++l+++
    EEA19323.1 312 PKDNARRGIESWRKLVAE 329
                   333334444444444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (333 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       497  (0.0277205); expected 358.6 (0.02)
Passed bias filter:                      464  (0.0258799); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2273.96
//
Query:       EEA19324.1  [L=328]
Description: gibberellin 20 oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.3e-17   61.9   0.0    1.2e-15   58.2   0.0    2.2  2  DIOX_N        non-haem dioxygenase in morphine synthesis N-te
    2.6e-16   60.0   0.0    4.4e-16   59.2   0.0    1.3  1  2OG-FeII_Oxy  2OG-Fe(II) oxygenase superfamily


Domain annotation for each model (and alignments):
>> DIOX_N  non-haem dioxygenase in morphine synthesis N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.2   0.0   1.4e-19   1.2e-15       1      97 [.      11     105 ..      10     119 .. 0.90
   2 ?    1.1   0.0     0.069   6.2e+02      32      65 ..     154     186 ..     139     198 .. 0.77

  Alignments for each domain:
  == domain 1  score: 58.2 bits;  conditional E-value: 1.4e-19
      DIOX_N   1 iPvidlsplsddedraavaeqlreAcrevGffyvvnhgvpeelidelfeaareFFalPeeeKeklakspsfrGysrlgeektdgkkldwkesfdlgt 97 
                 iP i l ++  +++ +++ +ql +A+++vGff v+ hg+++++i+++f+ ++ FF+l++++K  +  s ++ G+++ ++ + +++ +d kes++l+ 
  EEA19324.1  11 IPQISLLDF--ESRIDEITTQLIHAAENVGFFTVIDHGLSAADIENMFSNSQHFFELSDDVKATVPWSSKNVGWEKNAQVRPSTGMPDTKESYQLQF 105
                 566666655..677899**********************************************************9888888889*******99875 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.069
      DIOX_N  32 fyvvnhgvpeelidelfeaareFFalPeeeKekl 65 
                 f ++ h+v++   + + +++  +FalPee   k+
  EEA19324.1 154 FFIKAHDVSRPNSQTVCRLL-HYFALPEESDGKV 186
                 78999999998888888877.5899999976555 PP

>> 2OG-FeII_Oxy  2OG-Fe(II) oxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.2   0.0   4.9e-20   4.4e-16       4     101 .]     170     284 ..     167     284 .. 0.86

  Alignments for each domain:
  == domain 1  score: 59.2 bits;  conditional E-value: 4.9e-20
                   EEEEEE..E-S---------EEEEEESSSEEEEEEE-.TT---E..EEE.......TE.EEE----TTEEEEEE-HHHHHHTTS-S----EEE-.-- CS
  2OG-FeII_Oxy   4 llvlny..ypphpdpevilglgahtdaslltillqdd.vgglev..fkd.......gk.wlrvppvdnslivniGdallflsngryksvlHrVl.pv 86 
                   +++l+y  +p+  d  v  + gah d  +lt+l+q     gle+  +++       g+ w++++p +++++ niGd l+ +s+ r+ks++HrV+ p+
    EEA19324.1 170 CRLLHYfaLPEESDGKVYHRAGAHADWDFLTLLFQKAgQSGLEIcpGREvvtefgiGDvWTKIEPKTGEIVCNIGDLLMSWSDDRFKSTFHRVKaPS 266
                   6677777667777777777889**********************442447777889999***********************************777 PP

                   -GTGS...EEEEEEEE-- CS
  2OG-FeII_Oxy  87 neger...Rvsiayfiep 101
                   ++g+    R+sia+f +p
    EEA19324.1 267 EKGDYygdRYSIAFFNQP 284
                   77666999*******876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (328 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       417  (0.0232584); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.50
# Mc/sec: 1979.42
//
Query:       EEA19325.1  [L=722]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.5e-07   29.2  11.0    1.6e-06   28.1  11.0    1.5  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
     0.0029   16.7   1.3     0.0064   15.5   1.3    1.6  1  Fungal_trans  Fungal specific transcription factor domain
     0.0077   14.8   0.5      0.015   13.8   0.0    1.6  2  Cep3          Centromere DNA-binding protein complex CBF3 sub


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.1  11.0   2.7e-10   1.6e-06       3      31 ..      12      39 ..      10      43 .. 0.95

  Alignments for each domain:
  == domain 1  score: 28.1 bits;  conditional E-value: 2.7e-10
                -HHHHHCT---STSSSS-HHHHHCTHHHC CS
     Zn_clus  3 CdnCrkkKvKCdakkPaCsnCkklnleCt 31
                C +C ++KvKCd+  P C+nC  ++ +Ct
  EEA19325.1 12 CSECTRRKVKCDKTLP-CRNCLVKGINCT 39
                ****************.***********9 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   1.3   1.1e-06    0.0064      71     193 ..     290     409 ..     219     434 .. 0.72

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1.1e-06
  Fungal_trans  71 afplraeilihedfsspssslwilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktia 167
                    ++++ + ++ ++   ++ s+ ++q+   +     +++  ++h  ++  avr+a+s+gLhr  + v++++l++l ++ +e  rR+w +  ++  +++
    EEA19325.1 290 RWFQAMNLCLQYSDYMSTHSIFSVQAIATVTHSAHMLGHSNSHPVLLASAVRIAQSMGLHRLGAEVEDTDLQNL-ID-RELGRRVW-CQLCTQDWFS 383
                   34455555555555566666999999999999999999999**************************7766555.56.78888886.5678888888 PP

  Fungal_trans 168 lklGrppllddsqinlpLPcddddlw 193
                   + +   +l++ ++ n++ P + +d++
    EEA19325.1 384 IPFTESYLINRTSFNTAKPRNCNDED 409
                   88888888888888888664444333 PP

>> Cep3  Centromere DNA-binding protein complex CBF3 subunit B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.8   0.0   2.5e-06     0.015     108     207 ..     282     382 ..     272     395 .. 0.89
   2 ?   -2.6   0.1      0.23   1.4e+03     262     295 ..     607     640 ..     605     651 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2.5e-06
                 THHHHHHHHHHHHHHHHHHHTTTTTS--HHHHHHHHHHTTTTHHHHSHHHHHHHHHHHHHHHHTT-----S--TTS-HHHHHHHHHH.HHHHHHHHHHH CS
        Cep3 108 elqlelyegflkttitqlkkanfmanpdirliQiyliLsnTsflfeensladslllqclhvaKlfkiddfkplvedsaalrlskltl.eklwyrlcilD 205
                 + + el +   +++   l+ +++m++  i  +Q     +   ++  +++    ll  ++++a  + ++ + + ved+  ++l+   l +++w +lc++D
  EEA19325.1 282 DERKELSHRWFQAMNLCLQYSDYMSTHSIFSVQAIATVTHSAHMLGHSNSHPVLLASAVRIAQSMGLHRLGAEVEDTDLQNLIDRELgRRVWCQLCTQD 380
                 55677888888888889999********************************************************99998876665278********* PP

                 HC CS
        Cep3 206 Yl 207
                 ++
  EEA19325.1 381 WF 382
                 97 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 0.23
                 TTSSSSS---HHHHHHHHHHHHHHHHHHTS---T CS
        Cep3 262 qylakeskPslktLdaikreleilekkvsseeee 295
                   la+e++ + ktL  i+ + ei+++k+++++ +
  EEA19325.1 607 AMLANEQRIRRKTLHQIEPQNEIISNKTERRNID 640
                 5678888888999999999999999999765544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (722 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       726  (0.0404931); expected 358.6 (0.02)
Passed bias filter:                      517  (0.028836); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.70u 0.30s 00:00:01.00 Elapsed: 00:00:00.47
# Mc/sec: 4649.64
//
Query:       EEA19326.1  [L=578]
Description: purine permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.4e-51  175.5  31.3    6.5e-51  173.2  31.3    1.8  1  Xan_ur_permease  Permease family
    0.00028   21.3   5.6    0.00028   21.3   5.6    3.8  4  MFS_MOT1         Molybdate transporter of MFS superfamily


Domain annotation for each model (and alignments):
>> Xan_ur_permease  Permease family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  173.2  31.3   7.2e-55   6.5e-51       3     384 ..      85     505 ..      83     509 .. 0.90

  Alignments for each domain:
  == domain 1  score: 173.2 bits;  conditional E-value: 7.2e-55
                      HHHHHHHHHHHHHHHHHHHHHTTTS-...........H.HHHHHHHHHHHHHHHH.........HTTT-----EEE-GGGHHHHHGGG-..... CS
  Xan_ur_permease   3 llllglQhllamfaalvvvPllvgda.lgl.aeelrqlisatllasGiatllqll.........ifgirlpillgssfafvtalmialGsa... 82 
                      +++lglQh l+m++a+v +Pl ++     l +e++++l+sa+++++Giat lq++         ++g++l ++ g++f  + +   ++ +    
       EEA19326.1  85 TIILGLQHALTMVGAVVSPPLAIAGGaFYLtSEQTQYLVSAAFITTGIATALQVTrvhiaktpfYIGTGLLSVVGPTFDILNIAFNYTNMRyan 178
                      699******************998774556778888***************************99*************9999666555554677 PP

                      .............HHHHHHHHHHHHHHHHHHHHHHHTT-SH.HHHHH--HHHHHHHHHHHHHHHHHHHHHHTTSS-..BTT............. CS
  Xan_ur_permease  83 ...........edieialagllgallvagvlfilisltglrgrlarlipPvvtgpvvlliGlslaqiavkkvgggwaaveg............. 152
                                     +a +++lg++l  + +++l+sl+   + l r++p +vtg +++l+G +l+  ++++ gg     +g             
       EEA19326.1 179 gtcpvdetgakLPCPEAWGAMLGTMLCTVWVQFLMSLVPP-KILNRIFPKIVTGSLLVLVGVFLIGNGMENWGGSSNC-DGgtgfyalcpntaa 270
                      7789999998877889999999999999**********99.5****************************99987421.111122222222344 PP

                      ....B---HHHHHHHHHHHHHHHHHHHSSSTTTTTHHHHHHHHHHHHHHHHHHHTTSSHHHHS-SS-----------HH..H.HHHHTHHH.HH CS
  Xan_ur_permease 153 ...ltvvslkllllavvvllvilllsvflkglfsqlpiLigiiagwllalfmgivnlspevseapwfqlpsplkfgtplfnlgliltvlavalv 243
                         l+ +++kl++l++ v ++i+ + +f ++l+++ ++ +g+++g++++ + g  ++++ +++ap+ ++     f+ + ++ +l+l ++++++ 
       EEA19326.1 271 pnpLPWGDPKLIGLGFSVFVTIIFVEIFGSPLMRSASVIFGLAVGCAISGAAGYWSTDN-IDAAPVGTFLWVHTFKLS-VDRALVLPLMIMFVC 362
                      4558999****************************************************.99**99888666666666.899************ PP

                      HHHHHHHHHHHHHHHHTS-TII...IIIHHHHHHHHHHHHHHHHHHT---EEE-HHHHHHHHHHTB--HHHHHHHHHHHHHHT--HHHHHHHTT CS
  Xan_ur_permease 244 avvesvGdiravakvvgrslkp...kpdlrralladGlatllsgllGalpvttyaeniGvvaltkvasrrvmvtagvilillglipklaallss 334
                        v+ + di a+a+++g ++++   +++++ +++ dGl +l+s+l  +lp+ + a n+Gv++lt+ asrr + +a+ +l+l+g+++k++a + s
       EEA19326.1 363 EAVSCMPDILATAELSGVDIDGtefNSRIQGGIMCDGLCSLISALGTGLPMVSQAGNNGVISLTGCASRRAGWCASAFLVLMGIFGKFGAVFGS 456
                      *********************9***********************999********************************************** PP

                      S-HHHHHHHHHHHHHHHHHHHHHHHHHTTS-SHHHHHHHHHHHHHHHH-- CS
  Xan_ur_permease 335 IPepvlgGvllvvfgmiaasgvsnlqtvdldsarnllivavslvlGlgva 384
                       P  vlgG+ + ++++ia++g++ l+ v+++ +rn +i+  +l++G +  
       EEA19326.1 457 MPPSVLGGMQVFLYSTIAIAGIRVLSLVEFT-RRNRFILTAALGIGFIDI 505
                      *******************************.*************98765 PP

>> MFS_MOT1  Molybdate transporter of MFS superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   2.7      0.11     1e+03      43      86 ..      94     140 ..      80     159 .. 0.61
   2 ?    1.8   0.9     0.034     3e+02      87     109 ..     217     239 ..     194     241 .. 0.64
   3 ?   -2.5   0.1      0.73   6.5e+03      38      58 ..     302     322 ..     287     345 .. 0.68
   4 !   21.3   5.6   3.1e-08   0.00028      16     106 ..     369     468 ..     351     470 .. 0.83

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.11
    MFS_MOT1  43 tglfggvPmc..hgAgglaaqyrf.gartgaagillGlvllllgltg 86 
                 + ++g+v  +  ++Agg+     +  + +++a++++  +  +l +t+
  EEA19326.1  94 LTMVGAVVSPplAIAGGAFYLTSEqTQYLVSAAFITTGIATALQVTR 140
                 34455555557888888877655545555566666666666666665 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.034
    MFS_MOT1  87 llerllrliPksvlgglllgaGl 109
                   + l+r++Pk v g ll+ +G+
  EEA19326.1 217 PPKILNRIFPKIVTGSLLVLVGV 239
                 34567899999999999999997 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 0.73
    MFS_MOT1  38 lmnlltglfggvPmchgAggl 58 
                 lm  ++++fg    c+++g++
  EEA19326.1 302 LMRSASVIFGLAVGCAISGAA 322
                 455555555555556555543 PP

  == domain 4  score: 21.3 bits;  conditional E-value: 3.1e-08
    MFS_MOT1  16 nlvialaala.........slsltalllsvGlmnlltglfggvPmc..hgAgglaaqyrfgartgaagillGlvllllgltgllerllrliPksvlggl 103
                 + ++a+a l+         +  ++  ++  Gl+ l+++l  g+Pm   +g  g+++    g  +  ag + +++l+l+g++g + ++   +P svlgg+
  EEA19326.1 369 PDILATAELSgvdidgtefNSRIQGGIMCDGLCSLISALGTGLPMVsqAGNNGVISL--TGCASRRAGWCASAFLVLMGIFGKFGAVFGSMPPSVLGGM 465
                 5555666655666666666334666677789***************77788899999..9*************************************** PP

    MFS_MOT1 104 llg 106
                 +++
  EEA19326.1 466 QVF 468
                 *98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (578 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       510  (0.0284455); expected 358.6 (0.02)
Passed bias filter:                      274  (0.0152825); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 3887.07
//
Query:       EEA19327.1  [L=1184]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-53  182.6   0.2    1.7e-53  182.1   0.2    1.2  1  Amidohydro_1  Amidohydrolase family
    5.9e-20   71.4   0.0      9e-20   70.8   0.0    1.3  1  Fungal_trans  Fungal specific transcription factor domain
    7.9e-20   71.8   0.8    5.1e-15   55.9   0.1    2.7  3  Amidohydro_3  Amidohydrolase family
    3.9e-05   23.7   6.1    7.8e-05   22.7   6.1    1.5  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.014   14.8   0.2      0.085   12.2   0.0    2.0  2  A_deaminase   Adenosine/AMP deaminase


Domain annotation for each model (and alignments):
>> Amidohydro_1  Amidohydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  182.1   0.2   4.8e-57   1.7e-53       1     344 []      61     449 ..      61     449 .. 0.91

  Alignments for each domain:
  == domain 1  score: 182.1 bits;  conditional E-value: 4.8e-57
                   EEEE-EEEEEEECETTECSSS....GHHHHH..........STTHHHHHHHHHHHHHHHHTTEEEEEEEEHSSTHHHHHHHHHHHTSSSEEEEEEES CS
  Amidohydro_1   1 ivlPGlIDaHvHleqsllrga....tledwl..........vppetaaealesgiktalksGtttvadmgattstgiealleaaeelplglrilggk 83 
                   i++PGlI++H Hl qsllrg     +l++wl            +++ + a++  i+++lk Gtt ++d   t   g+e++ + + e+  g+r ++gk
    EEA19327.1  61 IIIPGLINTHAHLVQSLLRGLaedlPLHNWLcdaiwpletvYADDDGYNAARLTIAEMLKTGTTCFLDPMLTYRAGFERVCDVVGEM--GVRGCLGK 155
                   79***************************************99*************************9999888***********8..*******8 PP

                   SEGGS...........GCCCSHHHHHHHHHHHHHHHHHHCTTTCEEEEEEECGTCCSHHHHHHHHHHHHHHHTTEEEEEETSSCHHHHHHHHHHTTT CS
  Amidohydro_1  84 vsldr...........gsaetskasreklkagaaetikgkadgvvkvalapheapafsdeelkealkeakkrdlpvaiHaletkgevedaeaafget 169
                   ++  +           ++ +    s+ +l++      +g ++ ++ v+ a   + ++++++ +e+ ++++++++ +++H++e + + e  ++ +g  
    EEA19327.1 156 LVKFTetnrqlsitdpRDKDLIAMSIPALVEA-HAQHHGSHENRLHVWAAAGTPRGAPKSAFQELGDACSEHGISITMHCAEAPRDLEIYRDTYG-- 249
                   8766689******9984444444455555444.4555889999999*************************************************.. PP

                   EEEETTTTSTCC........HHTTTHCCEEEHCTCEEE.HHHHHHHHHHHHHHCEEHHHHHHHHSEHHHHHHHHHHHH..TSCEEEEEECTTSSCCG CS
  Amidohydro_1 170 iehgthlevaes........lglldeiklilahgvhlt.pteaellkerlkeagvahcpfsnsilrsgrealrkalde..GvkvglgtDgaasgnsl 255
                      +++ e+ ++        +g  ++ kl+lah+v l+  +++ ll     ++ vah p+sn++l+sg++++  +l     v+v+lgtDga + n  
    EEA19327.1 250 ---CSPMEFVKEthlccsqpIGSGKPRKLVLAHMVNLDlEKDIPLLSST--QTTVAHNPSSNLKLASGIAPVPSMLAHeeYVNVALGTDGAPCANHY 341
                   ...6888888888889999999999999**********888********..**********************9997755688************** PP

                   GHHHHHHHHHHHHHHCCTTTTHCHCHHHHHHHHHTHHHHHHTT-TTTSSSS-TTSB--EEEECC....CT.................CGGGTTTCTS CS
  Amidohydro_1 256 nlleelrlalklqrgllyedeegglslkealrmaTingAkalglddkvGsievGkdADlvvvdl....di.................laafvglkkd 331
                   ++++e+ la+ l++g++++  +  ++++ al+maTingA+algl+d+vGs+evGk+AD+vv+d+    +i                  +++v     
    EEA19327.1 342 DMFQEMHLAAILHKGVHND--ASLIPAETALEMATINGARALGLEDEVGSLEVGKKADMVVLDPygrgNIgiapwspnddnvdgvspVTTVVHGCTG 436
                   **************99994..56688888*********************************99888733668889999999999998888888888 PP

                   EEEEEEEETTEEE CS
  Amidohydro_1 332 gnvkkvivkGklv 344
                   + v++++v+G++v
    EEA19327.1 437 RDVDMTVVDGRIV 449
                   99********998 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.8   0.0   2.5e-23     9e-20       3     266 ..     682     918 ..     680     919 .. 0.82

  Alignments for each domain:
  == domain 1  score: 70.8 bits;  conditional E-value: 2.5e-23
  Fungal_trans   3 rffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeili...hedfsspssslwilqs 96 
                   ++f+n+hp fp+l++  +l+ +      +    +  l+  i+a+  l++++ t +s s + +     + + l+        ++df  p+   ++l +
    EEA19327.1 682 LYFDNVHPPFPVLDEKAILEAY------PQEGLPYTLVCEIYAVSLLLWRTSTTISASGRPTPD-VRYMWNLA----VsamNDDFIAPDL-STVLSC 766
                   7*********************......9999999999******************99999987.66644444....3444699999999.899998 PP

  Fungal_trans  97 LlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddlw 193
                    l l     ts + +++   +g +v+la+slgL+rnp ++       l + ++  r R+ww++ + D + +l +G pp+++ sq ++pLP+++  l+
    EEA19327.1 767 ILDLLGRPTTSITYNAV--NVGRVVSLAQSLGLNRNPLNWD------LAARQKNLRIRTWWGILIHDQWASLSHGTPPHIHHSQWDVPLPDSEI-LG 854
                   88888888888774444..58******************99......*******************************************9999.77 PP

  Fungal_trans 194 esddaseetlvetklsneeksrkiasfllaLkkilskiagsllsiekqlqqrdlqseklswveeleraldnWr 266
                     + + e            ++++ a+++ aL++++  i+g++l + + lq + +  +  + ++++e+ald+W 
    EEA19327.1 855 VGSITYEDPASV-------FRVQGALSFTALCQLTV-ILGEILPLIYALQPQASG-HAFRALRRHETALDEWE 918
                   777666666666.......56666666666665543.333355555555555555.5555************6 PP

>> Amidohydro_3  Amidohydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.0   1.1e-05      0.04       1      25 [.      53      77 ..      53      90 .. 0.87
   2 ?   -1.1   0.0      0.27   9.7e+02     147     285 ..      91     236 ..      75     239 .. 0.55
   3 !   55.9   0.1   1.4e-18   5.1e-15     354     473 .]     310     450 ..     289     450 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 1.1e-05
  Amidohydro_3  1 eviDakGrlvlPGFvDsHtHlaggg 25
                  ++iD+k+++ +PG++  H+Hl    
    EEA19327.1 53 QIIDCKNKIIIPGLINTHAHLVQSL 77
                  79******************98765 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.27
  Amidohydro_3 147 vldla.....plareaeaaavaaalaalasyGitsveagggnvsslddleplfeltaeeklplrviikelldaaerlglpls..pgseeltigavkl 236
                   ++d++      +a ++  +a++  +a++ + G t+     ++ ++++ +e++ ++  e    +r + ++l++  e  ++ +   p ++ l + ++ +
    EEA19327.1  91 LCDAIwpletVYADDDGYNAARLTIAEMLKTGTTCF--LDPMLTYRAGFERVCDVVGEM--GVRGCLGKLVKFTETNRQLSItdPRDKDLIAMSIPA 183
                   555555554333666667777888888888888888..455555555555555555553..344445555555555444444556666666666655 PP

  Amidohydro_3 237 fad......gvlgsrtalltepyf...........tgwpdfedealaelvaaadergldvaihaig 285
                   ++       g             +            + +  ++ a+ el +a+ e+g+ + +h+ +
    EEA19327.1 184 LVEahaqhhG-------------ShenrlhvwaaaGTPRGAPKSAFQELGDACSEHGISITMHCAE 236
                   5553333332.............1222234444422334444555889999999999999998865 PP

  == domain 3  score: 55.9 bits;  conditional E-value: 1.4e-18
  Amidohydro_3 354 argstpvkellnag..vkvalgsD..apvgpfdpwprigaavmrktrrggevlrpdeelsleealalyTrgpAkalgledrkGtLevGadADlvvld 446
                   a+g++pv ++l++   v+valg+D  +  + +d + +++ a  + +     v ++   ++ e+al + T ++A+algled+ G+LevG++AD vvld
    EEA19327.1 310 ASGIAPVPSMLAHEeyVNVALGTDgaPCANHYDMFQEMHLAAILHK----GVHNDASLIPAETALEMATINGARALGLEDEVGSLEVGKKADMVVLD 402
                   56677888888776559********666689999999999999999....7999******************************************* PP

  Amidohydro_3 447 ......adpldvdppelaear...............vrltvvdGrvvy 473
                         + ++   p+++  ++               v +tvvdGr+v+
    EEA19327.1 403 pygrgnIGIAPWSPNDDNVDGvspvttvvhgctgrdVDMTVVDGRIVV 450
                   ****995555555555555556799999999***************97 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   6.1   2.2e-08   7.8e-05       2      32 ..     497     529 ..     496     537 .. 0.86

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 2.2e-08
                 S-HHHHHCT---ST...SSSS-HHHHHCTHHHCC CS
     Zn_clus   2 aCdnCrkkKvKCda...kkPaCsnCkklnleCtf 32 
                 aCd Cr++K++C +   ++  C++C  ++++C+ 
  EEA19327.1 497 ACDFCRRRKSRCTQellNQS-CTECMMHQVPCSR 529
                 9*************984444.***********85 PP

>> A_deaminase  Adenosine/AMP deaminase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0      0.14   4.9e+02     168     200 ..     205     237 ..     198     244 .. 0.88
   2 ?   12.2   0.0   2.4e-05     0.085     233     298 ..     291     355 ..     277     377 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.14
                  CC-TTSTTGGGHHHHHCCCCHTT-EEEEEESSS CS
  A_deaminase 168 lndekiepaslflklraeagkstllltpHaGEa 200
                  ++ +++ p s f++l ++  ++++ +t+H+ Ea
   EEA19327.1 205 AGTPRGAPKSAFQELGDACSEHGISITMHCAEA 237
                  667788888889999***************998 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 2.4e-05
                  HHHHCT-EEEE-HHHHCCCSST-TTTT-CHHHHHHTT-EEEE--BS.CCCCT-SHHHHHHHHHHHHT CS
  A_deaminase 233 llalaqiplevcPlSNvalgafleyaenPlkeflerglnvslntDD.PlqfgttLieeYaiaaqvfk 298
                  ll+  q++++  P+SN +l     +a +P     e+ +nv+l+tD  P   ++++ +e++ aa  +k
   EEA19327.1 291 LLSSTQTTVAHNPSSNLKL--ASGIAPVPSMLAHEEYVNVALGTDGaPCANHYDMFQEMHLAAILHK 355
                  577889*************..8889999988889999********649999999********98776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1184 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       470  (0.0262145); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.80u 0.30s 00:00:01.10 Elapsed: 00:00:00.49
# Mc/sec: 7266.57
//
Query:       EEA19328.1  [L=517]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.6e-32  111.3  40.3    5.6e-32  111.0  40.3    1.1  1  MFS_1     Major Facilitator Superfamily
    3.7e-07   29.8  23.2    7.6e-07   28.7   9.2    2.2  2  MFS_4     Uncharacterised MFS-type transporter YbfB
  ------ inclusion threshold ------
      0.026   14.8   0.9      0.026   14.8   0.9    3.9  3  DUF4064   Protein of unknown function (DUF4064)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.0  40.3   9.3e-36   5.6e-32       3     353 .]      73     437 ..      71     437 .. 0.82

  Alignments for each domain:
  == domain 1  score: 111.0 bits;  conditional E-value: 9.3e-36
       MFS_1   3 laaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.sslwlllvlrvlqGlgag 100
                  +++l +++ s+l+ ++   l ++ +++ s++++l+++++++++va +p+G+l++     +v+   ++++++  l+++ a +s++ ++++r+l G++++
  EEA19328.1  73 GTYMLQYIDKSALAYSAVFDLFTTTHMTSSQYSWLASIFYFAYLVAEYPWGYLAQTTKMAKVVSGNVVAWGAI-LMITAAcTSFTGMAICRFLLGVFEA 170
                 689999******9999999888999******************************988888999999999999.555534588889************* PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg...Wravfyilaivsllafvlfllllpeepperkrkspkeee........ 188
                  ++p  + ++  w+++ e+++  g+++++++lGa++g ll+  + +      Wra+++il++v++l++vl l++lp++  + kr++ +++         
  EEA19328.1 171 PITPCFMLIVGMWYTRAEQPFRAGVFYSCNGLGAMIGGLLSFGIGQIKTiavWRAIYLILGGVTVLWGVLLLFFLPDDIMSAKRFTLEDKAlligrgrl 269
                 ****************************************999995555999*****************999999999999999988777799998666 PP

       MFS_1 189 ....kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlgls.glllaglllallalvgailallagrlsdrlgr.rrrlllal 281
                         + ++ + +++ + dp++w+l++ +l++ +++ g+ +++ l+++   g + + + +g+ ++++++++    l +++l+ r+++ r+  ++a+
  EEA19328.1 270 nrtgIINRRIKWYQ-IREAFIDPQVWMLFFFMLFNETINGGIASFSKLIIKGLTGDPlTTVALGIPFGAFQMLW---VLSGTYLASRIPNfRTVVMFAY 364
                 66555555555555.999********888888888889999*******84444444464466666666666666...6678888899888344444555 PP

       MFS_1 282 lllllaalglallavt..ssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfntagslggalgp 353
                 l+ +++ +++++  ++  + +v +l++++++G  +   + +l+  a++l +  ++ t +gl+ +a+++g ++gp
  EEA19328.1 365 LIPTIVGICMMW-KLShkTQKVGVLFGYYIVGAYVCSLVLALQMPATNLGGYTKRTTSVGLVFLAYCIGNIIGP 437
                 555555555555.3334699999999******9666666777777777777899*******************8 PP

>> MFS_4  Uncharacterised MFS-type transporter YbfB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.7   9.2   1.3e-10   7.6e-07      19     170 ..      93     246 ..      87     261 .. 0.79
   2 !    6.9   6.0   0.00057       3.4     262     361 ..     366     469 ..     329     471 .. 0.63

  Alignments for each domain:
  == domain 1  score: 28.7 bits;  conditional E-value: 1.3e-10
       MFS_4  19 llaegqlslsqagllaaaNylGYLvGallaafalsagaeRlrllagllatvllllamaltesfaaflliRflaGvasAvvlvfgsslvlahaaaarrer 117
                 l ++++++ sq ++la++ y  YLv      + ++  +   ++ + ++a  + l+  a+ +sf+ +++ Rfl+Gv  A +      +v    + a++++
  EEA19328.1  93 LFTTTHMTSSQYSWLASIFYFAYLVAEYPWGYLAQTTKMAKVVSGNVVAWGAILMITAACTSFTGMAICRFLLGVFEAPITPCFMLIVGMWYTRAEQPF 191
                 78899********************88866444444444444899999999999999******************999776555555555557789999 PP

       MFS_4 118 vgallfaGvGlGiavsgllvllllqlglsassl..Wlalavlsavllllvalllp 170
                   +++++  GlG +++gll   + q ++ a +   +l+l+ + ++  +l++  lp
  EEA19328.1 192 RAGVFYSCNGLGAMIGGLLSFGIGQIKTIAVWRaiYLILGGVTVLWGVLLLFFLP 246
                 99******************99999887666444467776666666666666666 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.00057
       MFS_4 262 allieavgvllsllsps.plglivssvllGltflait.alvlqlarelappatrrllglmTasfgigQilGplla..sllaeatgslalallvaaaalv 356
                 +  i +++++  l  ++  +g++ +  ++G+     + al ++++      ++ + +gl+ +++ ig i+Gp ++  +    +  +    l++++a +v
  EEA19328.1 366 IPTIVGICMMWKLSHKTqKVGVLFGYYIVGAYVCSLVlALQMPATNLGGYTKRTTSVGLVFLAYCIGNIIGPHAFlaNEAPIYQTGCRVILACSSAQAV 464
                 333445555555554431456677777777766554314444444444444557889***************875114444567788888999999999 PP

       MFS_4 357 laali 361
                 la+ +
  EEA19328.1 465 LAICL 469
                 99876 PP

>> DUF4064  Protein of unknown function (DUF4064)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   1.7     0.049   2.9e+02      82     102 ..     135     155 ..      65     156 .. 0.83
   2 ?   -2.4   2.3      0.96   5.7e+03      76      95 ..     224     243 ..     200     252 .. 0.56
   3 ?   14.8   0.9   4.4e-06     0.026      50      93 ..     346     389 ..     292     401 .. 0.81

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.049
     DUF4064  82 lkknkkvsGilfiiaailslf 102
                 +++n  ++G++++i+a+ + f
  EEA19328.1 135 VSGNVVAWGAILMITAACTSF 155
                 567788999999999998877 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.96
     DUF4064  76 ivgalllkknkkvsGilfii 95 
                  +  l+l + + ++G+l+++
  EEA19328.1 224 RAIYLILGGVTVLWGVLLLF 243
                 34444444444445555444 PP

  == domain 3  score: 14.8 bits;  conditional E-value: 4.4e-06
     DUF4064  50 asavleflstllivlgvialiaivlgivgalllkknkkvsGilf 93 
                  ++ ++ + ++ +v +++ li +++gi+ +++l++++ + G+lf
  EEA19328.1 346 GTYLASRIPNFRTVVMFAYLIPTIVGICMMWKLSHKTQKVGVLF 389
                 5666777889999****************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (517 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       702  (0.0391544); expected 358.6 (0.02)
Passed bias filter:                      287  (0.0160076); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 3479.52
//
Query:       EEA19329.1  [L=543]
Description: extracellular lipase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   4.4e-101  339.3   0.0   4.9e-101  339.1   0.0    1.0  1  COesterase     Carboxylesterase family
    5.4e-07   29.7   0.4    4.1e-06   26.8   0.4    2.2  1  Abhydrolase_3  alpha/beta hydrolase fold


Domain annotation for each model (and alignments):
>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  339.1   0.0  5.4e-105  4.9e-101       3     498 ..       8     507 ..       6     533 .. 0.91

  Alignments for each domain:
  == domain 1  score: 339.1 bits;  conditional E-value: 5.4e-105
                 SEEEETTEEEEEEEEEESTCSEEEEEEEEESSB---GGGTTS--BE----SSEEECBS---BESEECSSSSSCGHHCHHHBES---EEEEEEESSSSST CS
  COesterase   3 pvvetslGkvrGkrvklksekevdaFlGiPYAepPvgelRFkkPepaepwtgvrdAtkfspaCpqnaeksekeekeleawvsEDCLyLnvytPkekkea 101
                 p+v++++G+v G +++    ++v+aFlGiPYA pPv++lRF++P++  + ++v+dA+k++pa p +   +  +++e    +sEDCL++n++ P    ++
  EEA19329.1   8 PSVTLPQGTVVGVQLDNAFPQPVNAFLGIPYALPPVDDLRFRPPVKVPNSSKVIDASKYGPAAPGKGLLIGGPKVE----QSEDCLTVNIFRPG---SS 99 
                 89**************88888**********************************************999999976....9************5...56 PP

                 TSSEEEEEEE--STTTS-BGCGS-THHHHHHH..TSEEEEE----HHHHH-B-..SSTTSBS-HHHHHHHHHHHHHHHHGGGGTEEEEEEEEEEETHHH CS
  COesterase 102 kkklPVlVwihGggfqtgsaseydgsaLaaeg..nvivVtinYRlGvlGFlst..gdeeapGNvGllDqvlALrWVkenIasFGGdpervtlfGesAGa 196
                  +klPV ++ihGg++  gsa ++d  +++a      + V++ YRlG+lGFl    +++e   N+Gl Dq+l ++WV+enI++FGGdp +vtl+G sAGa
  EEA19329.1 100 CTKLPVAIYIHGGAYNRGSAMMHDTASMLAWSgePFVAVSFGYRLGALGFLPStlSKKEGLLNLGLHDQILLFQWVQENIEAFGGDPGNVTLIGLSAGA 198
                 8889******************9987776655478****************76467788888************************************* PP

                 HHHHHHHHSGGGT..TSBSEEEEES--TTSTTTSBSH...HHHHHHHHHHHTTS-CSSHH.HHHHHHHCS-HHHHHHCCGG.SSSSSSTTC-SSS-B-- CS
  COesterase 197 asvsllllsplsr..glfkraIlqSGsalspwaiqkk...arkrakklakkvgckasssk.elveclrsksaeelldaqek.aleasssklvsfaPvvd 288
                  s+  +ll    r   lf+r+I++SG+a+s ++  ++     ++++++ k+v+c+++  + e++ +lrs + + ++daq   + +++ s + +f+Pv+d
  EEA19329.1 199 HSIGHHLLNYDERckPLFHRVIIESGAATSRAVRPYDakvHEQQFQDFLKQVRCPENLPEsEIFPFLRSLPSSIITDAQIVvFDKWNPSLRWAFQPVID 297
                 ********95555549***************99888888999************6554444******************9966677889999******* PP

                 SSSSSS-HHHHHHCGC..CSEEEEEEETTTTHHHHCCHSTTTSSSSHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHSTTTSSTCHHHHHHHHHHHH CS
  COesterase 289 gdflpekPeellkseg..kvplliGvnkdegllflaylldkeksvkkkeeklsesllkdelyleaekkeelseaikeeytdeadrddaeksrkallell 385
                 gd++++kP+++ ks+   kvp+++G+n++eg++ + + + + ++     ++l  +l++ +l + ++   + + +  + yt++  ++   + +k++++++
  EEA19329.1 298 GDVISRKPLDAWKSKLwnKVPIMTGFNTNEGTMYVDKSMCHPEQFRGFWHTLLPDLSSADLDTIEKLYPDPNVEPNSPYTETRLEHGLGAQYKRIEAAY 396
                 **************66*************************999999999999999888877776668888899999***9999*************** PP

                 HHHHTHHHHHHHHHHHHHTT-SEEEEEEE--STTSSSTTTGSSBTTTTHHHHTTGGGTSGCSS-HHHHHHHHHHHHHHHHHHHHSSTTS.....TTSS- CS
  COesterase 386 tdvlfkapvlrtaklhasrgspvYlYsfdyrnssskkpkwmgvvhgdeleyvfglpllekeeftkedeklsrkmmtywtnFaktgnPnk.....eeeek 479
                 + + ++apv++ta+  +s+g pvYlY+            +  + h+d ++y   ++ +++   ++++++ls ++  y+t+F+++g+Pn       ++++
  EEA19329.1 397 GHYAYVAPVRQTAHFASSEGVPVYLYHWALAR-----TVVGRANHADNMYYETYNSNITSL--SESQKQLSGTLHAYITSFITKGDPNAisgldPQRPE 488
                 ****************************9988.....667778888888887766666554..778********************************* PP

                 ---B.TTTBEEEEESSSSS CS
  COesterase 480 Wpkytkeeekylkinlkpk 498
                 W++y ++e ++l +++ ++
  EEA19329.1 489 WKPYLPDEPRVLIFGQGNE 507
                 ********99999988765 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.4   4.5e-10   4.1e-06       2      95 ..     107     211 ..     106     252 .. 0.77

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 4.5e-10
                    EEE--STTTS--TTTTHHHHHHHHHHHTSEEEEEE---TTTS-TTH...........HHHHHHHHHHHHHHTHHHHTETTCEEEEEEETHHHHHHH CS
  Abhydrolase_3   2 vyfHGGGfvlgsldthdalcrelakelgavvvsvdYrlAPehpfPa...........avedalaalrwlaeqawelgadpsrivlaGdSaGGnlaa 86 
                    +y+HGG++  gs+ +hd+      +    v+vs  Yrl     +P             ++d +  ++w++e+ +++g dp +++l G SaG++   
     EEA19329.1 107 IYIHGGAYNRGSAMMHDTASMLAWSGEPFVAVSFGYRLGALGFLPStlskkegllnlGLHDQILLFQWVQENIEAFGGDPGNVTLIGLSAGAHSIG 202
                    8********************999**************976555541111111111167899999999999999******************9666 PP

                    HHHHHHHHT CS
  Abhydrolase_3  87 avalrarde 95 
                    + +l   ++
     EEA19329.1 203 HHLLNYDER 211
                    666665555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (543 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       273  (0.0152267); expected 358.6 (0.02)
Passed bias filter:                      262  (0.0146132); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 3744.44
//
Query:       EEA19330.1  [L=347]
Description: 1-aminocyclopropane-1-carboxylate deaminase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-42  146.0   0.1    1.7e-42  145.8   0.1    1.0  1  PALP      Pyridoxal-phosphate dependent enzyme
  ------ inclusion threshold ------
      0.057   12.7   0.0       0.11   11.8   0.0    1.4  1  LYTB      LytB protein


Domain annotation for each model (and alignments):
>> PALP  Pyridoxal-phosphate dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.8   0.1   1.9e-46   1.7e-42       4     292 ..      19     334 ..      16     336 .. 0.87

  Alignments for each domain:
  == domain 1  score: 145.8 bits;  conditional E-value: 1.9e-46
                 CSSS--EEEECCTCCCCCCE..EEEEEGGGST...TSBTTHHHHHHHHHH.HHTTTTTSEEEEEBSSHHHHHHHHHHHHHT-EEEEEEETTS-...... CS
        PALP   4 gigpTPlvrlprlskelgvp..lflKlEslnp...tgSfKdRgaeyllar.lkegtgaktvveassGNhgralAaaaallGlkvtivvpadas...... 90 
                   gp+P+  lp+++k+lg++  +++K+E++n     g++K+R++eyl ++ l++g+++ + + + ++Nh r +Aa+a  lG+kv +v +++++      
  EEA19330.1  19 LFGPSPIQYLPKITKALGGKvgIYAKREDCNSgfaYGGNKTRKLEYLASEaLAQGCDTLVSIGGVQSNHTRQVAAVATQLGMKVALVQEKWVNwedpay 117
                 579****************************7799***************99999********************************888888877777 PP

                 ..HHHHHHHHHTT-EEEEECCHHHHHHHH.HHHHHHH....STTCEE--TTT..SHHHHHHHHTHHHHHHHHTT....TTEEEEEEE-SSSHHHHHHHH CS
        PALP  91 ..pekvallrllGaevvevggdydeavaa.aaelaae....gegaylvsqfd..nptviegygtiglEileqlg....gkpdavvvpvGgGgliaGiaa 176
                   +++++l rl+Ga+v++ ++++  + +   ++l +e    g+++y+++ +   +p++ +g +  ++E+  q+       +d+v+v++ +G+++aG++a
  EEA19330.1 118 dkAGNIQLSRLMGADVRLDPSTFGIEHKDtLKNLKQEiigkGGKPYYIPAGAsdHPLGGLGFARWAFEVE-QQEkemgIFFDTVIVCAVTGSTMAGMVA 215
                 668****************9997766666567777777777*********99999**************5.44435548999***************** PP

                 HHHH...HSTT....-EEEEEEECTTCGGTTCCS..S.SS..B.SSS.CCSTCS....CGTTCCHHHHSEEEEEEEEEEHHHHHHHHHHHHHHHSB-B- CS
        PALP 177 glke...rrpd....vrvigvepegsdalarslragrrvtvpvsdtiadglavg....spselafelldrlvdeivtvsdeealeamrllarregivve 264
                 g+k    +  +     ++ig++++  +++ +++   + +++ v    a+g+++g      +e+++ l dr+   +++v+d++++ a++  a++e  +++
  EEA19330.1 216 GFKLaqkK--NgskpRKIIGIDAS--ATVKQTF--DQILRIAV----ATGVKIGltedDITEDDIILDDRYHAGVYGVPDQQTINAIKFGASTEAFITD 304
                 ****7663..1447889****876..8888888..44455555....445544454449999999999******************************* PP

                 H.HHHHHHHHH.HHHHHHCCTTCEEEEEEE CS
        PALP 265 p.ssaaalaal.klreagelkegdrvvvil 292
                 p + +++la++ + ++++el++g++++  +
  EEA19330.1 305 PvYEGKSLAGMmDIVQREELPAGSNILYAH 334
                 ***********************9999766 PP

>> LYTB  LytB protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   1.2e-05      0.11     188     228 ..      67     107 ..      57     121 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 1.2e-05
                 HHHHHGHSSEEEEES-TT-HHHHHHHHHHHHCSCTEEEESS CS
        LYTB 188 vkelakevdlvivvGgknSsNtkkLveiakeknkktylies 228
                  ++la+ +d+++ +Gg +S+ t++++ +a + + k+ l+++
  EEA19330.1  67 SEALAQGCDTLVSIGGVQSNHTRQVAAVATQLGMKVALVQE 107
                 5678888*************************999999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (347 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       373  (0.0208043); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.47
# Mc/sec: 2241.09
//
Query:       EEA19331.1  [L=334]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (334 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       551  (0.0307323); expected 358.6 (0.02)
Passed bias filter:                      533  (0.0297284); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.41
# Mc/sec: 2430.42
//
Query:       EEA19332.1  [L=199]
Description: hypothetical protein PMAA_001300 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (199 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       775  (0.0432261); expected 358.6 (0.02)
Passed bias filter:                      581  (0.0324056); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.49
# Mc/sec: 1209.94
//
Query:       EEA19333.1  [L=831]
Description: arginyl-tRNA synthetase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.3e-63  213.4   0.1    6.1e-63  212.9   0.1    1.1  1  tRNA-synt_1d  tRNA synthetases class I (R)
    1.9e-17   63.5   0.1    4.1e-17   62.4   0.1    1.6  1  DALR_1        DALR anticodon binding domain


Domain annotation for each model (and alignments):
>> tRNA-synt_1d  tRNA synthetases class I (R)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  212.9   0.1   6.7e-67   6.1e-63      18     348 ..     153     500 ..     145     501 .. 0.94

  Alignments for each domain:
  == domain 1  score: 212.9 bits;  conditional E-value: 6.7e-67
                   ST-EEEEE----BTTS--BHHHHHHHHHHHHHHHHHHHCT-EEEEEE--B-SSTCHHHHHHHHHHHTTTTTTS-----SCCCHHHHHHHHCCCSHC. CS
  tRNA-synt_1d  18 ekkkvvvdfssPniakemhvGhLrstiiGdavsrlleflGydvirlnhvGDWGtqfGlLiaylekkqdekllqeqelqdLeafykeakkdydeeei. 113
                    +kk++++fssPnia e+ + hLrsti+G  +++ +e +G+dv+rln++GDWG+ +GlL +  ek + e+l q  + ++L+++y+++   +  e+  
    EEA19333.1 153 GRKKLLIEFSSPNIASEFQARHLRSTILGAYIANQYENMGWDVTRLNYLGDWGKPMGLLGVAWEKFGSEELFQADPAGHLHDIYHKILELFVPEQAa 249
                   5799************************************************************************************999999889 PP

                   ...................CCHHHHHHHHHHHCT-HHHHHHHHHHHHHHHHHHHHHHHHCT---EC.--CC.CCCCCHHHHHHHHHCTT-EEECTTC CS
  tRNA-synt_1d 114 ...................faerarnyvvkLqsgdedirklwkllvditrtelqklydrldvtlie.rGes.lykeslneivkelkkkglvkesdGa 189
                                      faer   ++++++++de+   lwk+  d+  +++  ly+rl+v   e  Ges +  e++ e+ ++lk +g+ +es G 
    EEA19333.1 250 skkirdeggdpasiegqgvFAER-NAFFKRMEDDDEQAVALWKRARDVNIKNYTDLYARLNVRFDEySGESqVRLETMMEVEEILKSRGISEESAGS 345
                   9999**************77776.68*************************************99999***9999********************** PP

                   EEEEECCCTSSCCE.ECC-TTS-B-HHHHHHHHHHHHHHTT--SEEEEEEECCCH.HHHHHHHHHHHCTTSSTTTSEEEEEEE--EE-TTSSBSBCS CS
  tRNA-synt_1d 190 lvvfldefgkrlgv.vvqksDGgylytttDiaaakerkeelkadkvlyvidsrqs.lhlqqiflilkkigyvpeskdlehanfGmvlgkdkkkfktr 284
                    +++l++++k  g  +++ + G+ +y+ +D+aa+ er ++  +dk++yv+ + q+  h++++f il  ++    + +l+h +f  v      k++ +
    EEA19333.1 346 WMIDLKKHAKISGTaIIRDRTGSSTYLLRDLAAVLERSRKYSFDKMIYVVAADQHtTHFSRLFKILELMDMSDLANKLQHVQFSNV-----SKMSEK 437
                   **********99998999********************************9999746**************888************.....99**** PP

                   SSTC-BHHHHHHHHHHHHHHHHCCCCCCTS-CCCCHCHHHHHHHHHHHHCCCCTS-TTS-EE-- CS
  tRNA-synt_1d 285 kGetvkLadlLdealeralqlikeknkdkvlqadelekvaeavgvgaikyaDlsknrindyifd 348
                    G+   L+++Ld+  +   +  k + ++  +   + e+ + +++++a+   +ls++r +d  f+
    EEA19333.1 438 FGNDRTLDEILDQFQKAMCESFKIHPEM-ASLLGHSEESIFSIAISALVAGELSSKRAQDNAFE 500
                   ************9777666766666666.6667778888899******************9986 PP

>> DALR_1  DALR anticodon binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.4   0.1   4.6e-21   4.1e-17       1     116 [.     515     624 ..     515     626 .. 0.92

  Alignments for each domain:
  == domain 1  score: 62.4 bits;  conditional E-value: 4.6e-21
                 HHHHHHHHHHHHHHTTCTTCCCCHCCHCCS-SHHHHHHHHHHHTHHHHHHHHHHHT-THHHHHHHHHHHHHHHHHHHHCTSTTSCTHHH.HHHHHHHHH CS
      DALR_1   1 vqyahaRiksilrkaeeegekleeealalleeeeekeLlkalaqfpevleeaaeelephklaeylyeLaatfhkfYnkervlkeeeeelaaaRLaLvka 99 
                 +qy +aR+++il  +e++ + +eee + l  ++e+  Ll+ l qfp++   a e+lep +++ yl +La +   +++++  + +++ ++     +L +a
  EEA19333.1 515 LQYWYARLCTILDAYETSIKPSEEEFDTL--SDEDFSLLRLLVQFPDITHLAYESLEPATVMAYLVNLAVQLEVCFDECENNVANNLTQ----ANLYEA 607
                 69***********9999999999998888..99********************************************997666666544....78**** PP

                 HHHHHHHHHHHTT---- CS
      DALR_1 100 vrqvLangLdlLGieap 116
                 +r+v+++g++lLGi ++
  EEA19333.1 608 TRRVMESGMKLLGIIPV 624
                 **************876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (831 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       659  (0.0367561); expected 358.6 (0.02)
Passed bias filter:                      568  (0.0316805); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.66u 0.28s 00:00:00.94 Elapsed: 00:00:00.43
# Mc/sec: 5863.38
//
Query:       EEA19334.1  [L=358]
Description: lipase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.8e-45  153.0   0.0    1.3e-44  152.5   0.0    1.2  1  Abhydrolase_3  alpha/beta hydrolase fold
    6.2e-05   22.1   0.1    0.00043   19.3   0.1    1.9  1  COesterase     Carboxylesterase family
  ------ inclusion threshold ------
      0.021   14.3   0.0        1.2    8.6   0.0    2.2  2  Peptidase_S9   Prolyl oligopeptidase family


Domain annotation for each model (and alignments):
>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  152.5   0.0   2.3e-48   1.3e-44       2     209 ..      94     319 ..      93     321 .. 0.88

  Alignments for each domain:
  == domain 1  score: 152.5 bits;  conditional E-value: 2.3e-48
                    EEE--STTTS--TTTTHHHHHHHHHHHTSEEEEEE---TTTS-TTHHHHHHHHHHHHHHHTHHHHTETTCEEEEEEETHHHHHHHHHHHHHHHTT. CS
  Abhydrolase_3   2 vyfHGGGfvlgsldthdalcrelakelgavvvsvdYrlAPehpfPaavedalaalrwlaeqawelgadpsrivlaGdSaGGnlaaavalrardeg. 96 
                    ++fH GGf+ gsl+++d+lc+ +a +l++ v+ ++Yr  Pe+ +P+a +da + + wl ++a++++ad  riv++G SaG++l+a +++ ++ +  
     EEA19334.1  94 MHFHSGGFLYGSLQSEDPLCSIVALRLNILVLHINYRHTPEYTYPTAWNDAEDGMIWLCKNASNINADLGRIVIGGSSAGAHLSASLTRILATQPa 189
                    78**************************************************************************************66666521 PP

                    ---......EEEEEEESE........-SST..SSTTSHHHHHCHHTTTSSSSCHHHHHHHHHHHS.SGGGGGSTTTSGGGC..S-SST---EEEEE CS
  Abhydrolase_3  97 epk......vagqvliyP........vtdl..ertesesikkaeeladgplltraaldlfwrlyl.peadrddplasplla..edlsglpptlvvv 173
                    +++      + gqvl+ P              ++ + +s  + ++ a++++l +++ ++f ++   +  d +d +++p +   e+ s++pp++ ++
     EEA19334.1 190 QLQlspqptICGQVLMIPslvfgdcyE--SqmRQIKDPSLSSYNQCAEASFLDTKTRKMFNDALKvESPDPNDKRLNPGHLtaEEASKMPPATFAI 283
                    333788899*********999766642..14567777777666888******98888888877764599999*****98665357*********** PP

                    ETT-TTHHHHHHHHHHHHHTT--EEEEEETTEETTG CS
  Abhydrolase_3 174 aefDplrdegeayaerlraagvevelieyegmvHgf 209
                    a++Dp rdeg  ya+ l ++gv++++++++g++Hgf
     EEA19334.1 284 AGYDPVRDEGLLYAKLLTEQGVPTDVHVFKGLPHGF 319
                    ***********************************9 PP

>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.1   7.2e-08   0.00043     101     201 ..      86     179 ..      80     193 .. 0.84

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 7.2e-08
                 TTSSEEEEEEE--STTTS-BGCG..S-THHHHHHHTSEEEEE----HHHHH-B-SSTTSBS-HHHHHHHHHHHHHHHHGGGGTEEEEEEEEEEETHHHH CS
  COesterase 101 akkklPVlVwihGggfqtgsase..ydgsaLaaegnvivVtinYRlGvlGFlstgdeeapGNvGllDqvlALrWVkenIasFGGdpervtlfGesAGaa 197
                 a+ klPV + +h ggf +gs ++    +s  a + n++v  inYR            e +   +  D    + W+ +n ++ + d  r+ + G+sAGa 
  EEA19334.1  86 ADGKLPVYMHFHSGGFLYGSLQSedPLCSIVALRLNILVLHINYRHT---------PEYTYPTAWNDAEDGMIWLCKNASNINADLGRIVIGGSSAGAH 175
                 56789***************977446678999999**********54.........4556667889********************************8 PP

                 HHHH CS
  COesterase 198 svsl 201
                 + + 
  EEA19334.1 176 LSAS 179
                 6554 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0    0.0069        41      43      79 ..     142     178 ..     135     185 .. 0.80
   2 ?    8.6   0.0    0.0002       1.2     159     195 ..     290     326 ..     233     336 .. 0.81

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.0069
                   HHHHHHHHHHHHHHHTTS--GGGEEEEEETHHHHHHH CS
  Peptidase_S9  43 nefdDfiaaaealakegyvdserlaitGgSyGGyltg 79 
                   n+++D + ++ + a++  +d  r++i G S+G  l++
    EEA19334.1 142 NDAEDGMIWLCKNASNINADLGRIVIGGSSAGAHLSA 178
                   556666666666777778999***********98876 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.0002
                   THHHHHHHHHHH--S-SEEEEEETTS-SSTTSSHHHH CS
  Peptidase_S9 159 paealklvaaLqkkgknvlllifpdegHgvgkprakv 195
                     e+l +++ L+++g+++++++f++  Hg+++  +k 
    EEA19334.1 290 RDEGLLYAKLLTEQGVPTDVHVFKGLPHGFRMMGNKL 326
                   5789999************************998886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (358 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       361  (0.020135); expected 358.6 (0.02)
Passed bias filter:                      338  (0.0188521); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2409.75
//
Query:       EEA19335.1  [L=397]
Description: endochitinase precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.6e-22   80.7   1.4      4e-22   79.3   1.4    1.5  1  Glyco_hydro_18  Glycosyl hydrolases family 18
    5.3e-09   35.9  12.5    5.3e-09   35.9  12.5    3.1  2  CBM_1           Fungal cellulose binding domain


Domain annotation for each model (and alignments):
>> Glyco_hydro_18  Glycosyl hydrolases family 18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.3   1.4   4.5e-26     4e-22       2     309 ..      33     306 ..      32     310 .. 0.73

  Alignments for each domain:
  == domain 1  score: 79.3 bits;  conditional E-value: 4.5e-26
                     EEEEEEGGGGGSS.G.....C.SHTTTESEEEEEEEEEEE...........TTTEEEESSTTHHHHHHHHHHHH.HHTSTT-EEEEEEEETTTTT CS
                     xxxxxxxxxxxxx.x.....x.xxxxxxxxxxxxxxxxxx...........xxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18   2 vvgYysswesygn.n.....y.lpsaklthiiyaFakidg...........engkvvvsdwedlgnfeqlkklk.kkknpgvkvllsiGGwtdss 77 
                     vv+Y++++++ +  n     y   s++++++++aF+   g           ++ ++++s   +  n  +l+++  + +++gvkv+ls+GG+ +  
      EEA19335.1  33 VVVYWGQNAAAASeNndlstYcTSSSGIDIVVLAFLYEYGngitipsgvigQDCSISTSG--QGSNCGNLARQIsTCQSHGVKVILSLGGAVG-- 123
                     89***9999886555565543455************998877777777776443444333..336778888888899999************9.. PP

                     HHHHHHTSHHHHHHHHHHHHHHH.........HHCT...-SEEEEEES-TTTSTCHHHHHHHHHHHHHHHHH.HHHHHTSTTCEEEEEEESSHHH CS
                     xxxxxxxxxxxxxxxxxxxxxxx.........xxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18  78 gfslaastdasrkkfadsvvsll.........rkyg...fDGiDidweypggnpedkenytallkelreald.kakategkkllLsaavpasasd 159
                     ++sl+  ++a++++  + +++ +         r++g   + G D+d+e  +g    ++ y+ ++++lr+ +  +       +++++ a++++ ++
      EEA19335.1 124 AYSLT--SQAEAETIGQHLWDAYgntsggsipRPFGsvfVNGWDFDIEASSG----NQYYQYMISKLRSNFAsDS----AHTYYITGAPQCPVPE 208
                     88888..469*************9888888888888************8777....9************998443....589************* PP

                     HHHHCHHHHHHHHT..SEEEEETTTSSSTTSSBE--SS-SSBTCSSHHHHHHHHHHTT--GG..GEEEEEESEEEEEEESSSSSSTSTTTEEEHH CS
                     xxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18 160 lskgydlpkiakyl..DyvnvmtYDfhgswdnvtghhaplydaslnvdeavkeylkagvpak..klvlGvpfygrawalvsgadntkeegvlsyk 250
                          ++ +i  +   Dy+++++Y  +++   +  ++     ++ln ++ v ++   g+p++  kl+lGvp++  + ++++              
      EEA19335.1 209 P----NMGQIITAAqfDYLWIQFY--NNP---YCSYP-----NTLNYHDWVSYVS--GTPSAhaKLFLGVPASELGSTGTQS------------- 274
                     3....44444444445********..443...22222.....2345555453333..6663337*********888877554............. PP

                     HHHHHHTEEEEEEEEETTTTEEEEEETTEEEEE-SHHHHHHHH.HHHHHTTESEEEEETG CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx RF
  Glyco_hydro_18 251 elkellkkakakrkydskakapyvydgeefvsyDdpksikaka.dyvkakglgGvmiWsl 309
                                        +a y         y +p+ +++ +  +  +++ gG+m+W++
      EEA19335.1 275 -------------------GAVY---------YQSPSVLASTVaSFDTSSNWGGIMMWDA 306
                     ...................2333.........3577777777766666666777777765 PP

>> CBM_1  Fungal cellulose binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1      0.27   2.5e+03       5       9 ..     333     337 ..     332     351 .. 0.87
   2 !   35.9  12.5   5.9e-13   5.3e-09       1      29 []     365     393 ..     365     393 .. 0.97

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.27
       CBM_1   5 CGGig 9  
                 CGG+g
  EEA19335.1 333 CGGTG 337
                 9*987 PP

  == domain 2  score: 35.9 bits;  conditional E-value: 5.9e-13
       CBM_1   1 lwgQCGGigWtGpTtCvsgatCtyqNeyY 29 
                 +wgQCGG+g+tG+T+C+s++ C++ + ++
  EEA19335.1 365 QWGQCGGQGYTGSTVCASPYHCVTESIWW 393
                 7***********************99998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       540  (0.0301188); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.31s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 2532.71
//
Query:       EEA19336.1  [L=505]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.5e-32  112.2  35.5    1.3e-31  109.8  34.0    2.0  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  109.8  34.0   7.4e-36   1.3e-31       1     353 []      59     425 ..      59     425 .. 0.89
   2 !    7.1   0.5   0.00012       2.2     104     187 ..     390     477 ..     389     498 .. 0.72

  Alignments for each domain:
  == domain 1  score: 109.8 bits;  conditional E-value: 7.4e-36
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll..fasslwlllvlrvlqGl 97 
                 ++l++fl +++  i++ a+ + ++ +l + +  +  + t +++++++a +p  +l +++ + ++l + +l+++++ ++++  +  ++++l+v+rv+ Gl
  EEA19336.1  59 MFLCYFLQFIDKVIINYAAVMGISAELKLVGNDFTNASTSFFIAYLIAEVPNTFLLQKVPAGKWLGFNVLIWGVA-VAATggV-KGYTTLVVARVFLGL 155
                 59*************************************************************************.4444235.9999*********** PP

       MFS_1  98 gagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg.....Wravfyilaivsllafvlfllllpeepperkrkspkeee... 188
                 +++++ p+ +++ +++++k+e++  ++++++g +++ i+g l++  + +  g     Wr +f++l+i++ +++ ++++++p++p + +  +++e+    
  EEA19336.1 156 FEATIGPSLMIISSQYYTKQEQAPRFSFWYLGLGVAQIIGGLISFGFQHVHGasisgWRIMFIVLGIFTSIVGTVVFFFIPDTPMKASFLTEVEKVall 254
                 ****************************************99999766555566777*****************999*************999999887 PP

       MFS_1 189 .........kgtgpaplvpawkallkdpvlwillialllfffgfsg.lltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrl 277
                          ++  +++ +++++a+l  + +w+l ++++l + + sg ++t++ + l   +g+s    a+ll + +++v++i+ l++g  +++  +r+++
  EEA19336.1 255 rhvsenktgVWNNKFSYKQIFEAILDVQ-VWLLTLMVVLQS-VSSGvVTTYSST-LIRNMGFS-SQHAALLNMPSGVVSIISTLVVGIGIRKAENRWAW 349
                 7776665555555555555666666666.574555555555.444459999999.6*******.688888899999999999***************** PP

       MFS_1 278 llallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfntagslggalgp 353
                 + ++++  ++  gl+ + + s+++ +l++++l+   ++   +++   a++ a+  ++++ s+l+   +s+g ++gp
  EEA19336.1 350 IATCSIPGIIGGGLMSFLPKSNKAGCLIGIYLVNAIVAPLPVIYHWTAANCAGYTKRAFCSALIAGSFSIGNIIGP 425
                 ****************************************999999*****************************8 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.00012
       MFS_1 104 pagaaliadwfpk.eergraigllsagfslGailgpllggllasslg....Wravfyilaivsllafvlfllllpeepperkrkspkee 187
                 p+++ ++a+  ++ ++r++  +l++++fs+G i+gp    +   +        av +  a+++++a+vlf+ +++e++++ +r+  ++ 
  EEA19336.1 390 PVIYHWTAANCAGyTKRAFCSALIAGSFSIGNIIGPQTFQARD-APDyhpaKIAVLVTQAAAGVMAVVLFGYYIWENKRRDARDVAEPM 477
                 5566666667777789*******************86544443.333224444557788888888888999999999998888776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (505 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       836  (0.0466284); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.27s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 3272.91
//
Query:       EEA19337.1  [L=366]
Description: integral membrane protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
        3.2    7.4   5.8       0.76    9.3   1.6    2.2  2  DUF4044        Protein of unknown function (DUF4044)
        7.4    6.9   6.7         17    5.7   0.2    2.7  3  Cytochrom_B_C  Cytochrome b(C-terminal)/b6/petD


Domain annotation for each model (and alignments):
>> DUF4044  Protein of unknown function (DUF4044)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   1.6   8.5e-05      0.76      18      31 ..      54      67 ..      54      69 .. 0.90
   2 ?   -3.0   0.1      0.63   5.6e+03       4      13 ..     315     324 ..     315     325 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 8.5e-05
     DUF4044 18 lMliaTVGSvllga 31
                +M++a+V+S++++ 
  EEA19337.1 54 IMAVAMVFSIIYAT 67
                8**********986 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.63
     DUF4044   4 kKStFqKiTk 13 
                 ++St++K T 
  EEA19337.1 315 PTSTVSKRTV 324
                 589**99775 PP

>> Cytochrom_B_C  Cytochrome b(C-terminal)/b6/petD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.2    0.0019        17      33      82 ..      19      69 ..       9      82 .. 0.79
   2 ?   -2.8   0.1      0.88   7.9e+03      30      80 ..     128     141 ..     110     153 .. 0.52
   3 ?    4.5   0.2    0.0048        43      24      69 ..     203     248 ..     179     276 .. 0.71

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0019
                   HHHHHHHHHHGGGCHHHH---SSSSSTT-.HHHHHHHHH.HHHHHHHHHHH CS
  Cytochrom_B_C 33 Gvvamgaaivilfllpwldrskvksiryrkplakvllal.lvvsfvvLgyl 82
                    ++a+ + + +l++l +  r  v+  ++r+ l  +++a+ +v+s++  +++
     EEA19337.1 19 AIIAVCIVLTLLMTLTVSTRIAVRWRQHRTGLDDYIMAVaMVFSIIYATLC 69
                   58899999999999999999*********9999998887355555555444 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.88
                    HHHHHHHHHHHHHGGGCHHHH---SSSSSTT-.HHHHHHHHHHHHHHHHHH CS
  Cytochrom_B_C  30 kllGvvamgaaivilfllpwldrskvksiryrkplakvllallvvsfvvLg 80 
                    kl                                       +++++++++ 
     EEA19337.1 128 KLYR-------------------------------------IIIITIAAIS 141
                    3333.....................................3333333333 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.0048
                    HHCSSSHHHHHHHHHHHHHGGGCHHHH---SSSSSTT-.HHHHHHH CS
  Cytochrom_B_C  24 LraipakllGvvamgaaivilfllpwldrskvksiryrkplakvll 69 
                    L++ pa+ +G++a++   +   +  +l   +++ i+y +  +++l+
     EEA19337.1 203 LKVRPAQRAGIIALFSLGLFTTVCSILRMTQIRVIAYGNGNSTLLV 248
                    4555777778888888777777777888888887777755544444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (366 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       639  (0.0356406); expected 358.6 (0.02)
Passed bias filter:                      346  (0.0192983); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.66u 0.34s 00:00:01.00 Elapsed: 00:00:00.57
# Mc/sec: 1944.43
//
Query:       EEA19338.1  [L=364]
Description: integral membrane protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
        3.1    7.4   5.8       0.75    9.4   1.6    2.2  2  DUF4044        Protein of unknown function (DUF4044)
        8.1    6.8   6.8         17    5.8   0.2    2.8  4  Cytochrom_B_C  Cytochrome b(C-terminal)/b6/petD


Domain annotation for each model (and alignments):
>> DUF4044  Protein of unknown function (DUF4044)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   1.6   8.4e-05      0.75      18      31 ..      54      67 ..      54      69 .. 0.90
   2 ?   -3.0   0.1      0.62   5.6e+03       4      13 ..     313     322 ..     313     323 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 8.4e-05
     DUF4044 18 lMliaTVGSvllga 31
                +M++a+V+S++++ 
  EEA19338.1 54 IMAVAMVFSIIYAT 67
                8**********986 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.62
     DUF4044   4 kKStFqKiTk 13 
                 ++St++K T 
  EEA19338.1 313 PTSTVSKRTV 322
                 589**99775 PP

>> Cytochrom_B_C  Cytochrome b(C-terminal)/b6/petD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.2    0.0019        17      33      82 ..      19      69 ..       9      82 .. 0.79
   2 ?   -2.8   0.1      0.88   7.9e+03      30      80 ..     128     141 ..     110     153 .. 0.52
   3 ?    3.4   0.2     0.011        95      24      65 ..     203     244 ..     190     259 .. 0.75
   4 ?    0.6   0.1     0.076   6.8e+02      17      84 ..     222     302 ..     221     309 .. 0.69

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0019
                   HHHHHHHHHHGGGCHHHH---SSSSSTT-.HHHHHHHHH.HHHHHHHHHHH CS
  Cytochrom_B_C 33 Gvvamgaaivilfllpwldrskvksiryrkplakvllal.lvvsfvvLgyl 82
                    ++a+ + + +l++l +  r  v+  ++r+ l  +++a+ +v+s++  +++
     EEA19338.1 19 AIIAVCIVLTLLMTLTVSTRIAVRWRQHRTGLDDYIMAVaMVFSIIYATLC 69
                   58899999999999999999*********9999998887355555555444 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.88
                    HHHHHHHHHHHHHGGGCHHHH---SSSSSTT-.HHHHHHHHHHHHHHHHHH CS
  Cytochrom_B_C  30 kllGvvamgaaivilfllpwldrskvksiryrkplakvllallvvsfvvLg 80 
                    kl                                       +++++++++ 
     EEA19338.1 128 KLYR-------------------------------------IIIITIAAIS 141
                    3333.....................................3333333333 PP

  == domain 3  score: 3.4 bits;  conditional E-value: 0.011
                    HHCSSSHHHHHHHHHHHHHGGGCHHHH---SSSSSTT-.HHH CS
  Cytochrom_B_C  24 LraipakllGvvamgaaivilfllpwldrskvksiryrkpla 65 
                    L++ pa+ +G++a++   +   +  +l   +++ i+y +  +
     EEA19338.1 203 LKVRPAQRAGIIALFSLGLFTTVCSILRMTQIRVIAYGNGNS 244
                    566688889999999998888888899999888888874444 PP

  == domain 4  score: 0.6 bits;  conditional E-value: 0.076
                    GHHHHHHHHCSS.............SHHHHHHHHHHHHHGGGCHHHH---SSSSSTT-.HHHHHHHHHHHHHHHHHHHHHT CS
  Cytochrom_B_C  17 flpfYaiLraip.............akllGvvamgaaivilfllpwldrskvksiryrkplakvllallvvsfvvLgylGv 84 
                    f+++ +iLr+++               l+G + +   i  +  l  l r+ v+ + yr  + +   ++  ++ ++L  +G+
     EEA19338.1 222 FTTVCSILRMTQirviaygngnstlLVLWGTIEFNNIITSVPYLAPLFRRWVSDFGYRIGYGSRSHTVRTTENYILKSYGK 302
                    778888999974444455555544477889988888888888888888888888888876666666666666666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (364 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       641  (0.0357521); expected 358.6 (0.02)
Passed bias filter:                      339  (0.0189079); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.36s 00:00:01.01 Elapsed: 00:00:00.56
# Mc/sec: 1953.79
//
Query:       EEA19339.1  [L=263]
Description: integral membrane protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
       0.12   11.9   1.6       0.51    9.9   1.6    2.1  1  DUF4044        Protein of unknown function (DUF4044)
        1.4    9.2   5.4         10    6.5   0.2    2.7  3  Cytochrom_B_C  Cytochrome b(C-terminal)/b6/petD


Domain annotation for each model (and alignments):
>> DUF4044  Protein of unknown function (DUF4044)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   1.6   5.7e-05      0.51      18      31 ..      54      67 ..      54      69 .. 0.90

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 5.7e-05
     DUF4044 18 lMliaTVGSvllga 31
                +M++a+V+S++++ 
  EEA19339.1 54 IMAVAMVFSIIYAT 67
                8**********986 PP

>> Cytochrom_B_C  Cytochrome b(C-terminal)/b6/petD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.2    0.0011        10      33      82 ..      19      69 ..       9      82 .. 0.79
   2 ?   -1.9   0.1      0.46   4.1e+03      30      80 ..     128     141 ..     106     157 .. 0.56
   3 ?    4.7   0.1    0.0041        36      24      61 ..     203     240 ..     178     257 .. 0.64

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0011
                   HHHHHHHHHHGGGCHHHH---SSSSSTT-.HHHHHHHHH.HHHHHHHHHHH CS
  Cytochrom_B_C 33 Gvvamgaaivilfllpwldrskvksiryrkplakvllal.lvvsfvvLgyl 82
                    ++a+ + + +l++l +  r  v+  ++r+ l  +++a+ +v+s++  +++
     EEA19339.1 19 AIIAVCIVLTLLMTLTVSTRIAVRWRQHRTGLDDYIMAVaMVFSIIYATLC 69
                   5889999999999999999**********9999998887355555555444 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.46
                    HHHHHHHHHHHHHGGGCHHHH---SSSSSTT-.HHHHHHHHHHHHHHHHHH CS
  Cytochrom_B_C  30 kllGvvamgaaivilfllpwldrskvksiryrkplakvllallvvsfvvLg 80 
                    kl                                     + +++++++++ 
     EEA19339.1 128 KL-------------------------------------YRIIIITIAAIS 141
                    22.....................................223333333332 PP

  == domain 3  score: 4.7 bits;  conditional E-value: 0.0041
                    HHCSSSHHHHHHHHHHHHHGGGCHHHH---SSSSSTT- CS
  Cytochrom_B_C  24 LraipakllGvvamgaaivilfllpwldrskvksiryr 61 
                    L++ pa+ +G++a++   +   +  +l   +++ i+y 
     EEA19339.1 203 LKVRPAQRAGIIALFSLGLFTTVCSILRMTQIRVIAYG 240
                    44456666666666666666666666666666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (263 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       814  (0.0454013); expected 358.6 (0.02)
Passed bias filter:                      402  (0.0224218); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.32s 00:00:00.96 Elapsed: 00:00:00.55
# Mc/sec: 1450.90
//
Query:       EEA19340.1  [L=403]
Description: FAD binding domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-16   60.9   0.0    1.7e-15   57.1   0.0    2.3  1  FAD_binding_3  FAD binding domain
    3.6e-06   27.1   0.1    8.7e-06   25.9   0.1    1.7  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
    0.00042   20.0   0.1    0.00091   18.9   0.1    1.6  1  DAO            FAD dependent oxidoreductase
     0.0063   15.8   0.0      0.017   14.4   0.0    1.7  1  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
     0.0086   15.3   0.0      0.015   14.5   0.0    1.3  1  Thi4           Thi4 family
  ------ inclusion threshold ------
      0.014   16.0   0.0        0.1   13.2   0.0    2.2  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
      0.036   14.3   0.0      0.092   13.0   0.0    1.7  1  TrkA_N         TrkA-N domain
       0.18   11.7   0.0          2    8.3   0.0    2.1  2  3HCDH_N        3-hydroxyacyl-CoA dehydrogenase, NAD binding d


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.1   0.0   7.6e-19   1.7e-15       3     324 ..       8     344 ..       6     378 .. 0.71

  Alignments for each domain:
  == domain 1  score: 57.1 bits;  conditional E-value: 7.6e-19
                    EEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSSS--EEE.HHHHHHHHHTT-HHHHHHHSEECCCCEEEEEEECCCCCEEEEEHHCHHCST CS
  FAD_binding_3   3 dVlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlpradgln.qrtmellrqlGledrilaegapnelmgealynelsdtpkaradlelesspe 97 
                    ++lIVGaG +Gl+la+ L++ G+  ++ ++ ++ v  + + gl+    +  l++l  e+ +++ g  n +   a  +     + + +dl+   +  
     EEA19340.1   8 PILIVGAGISGLSLAQYLRKSGIPFRIFDRDASIVSRTGGWGLTfHWGLPALKELLPEELYERLGECNVN-PNAQDAG----KYRFLDLK-TGESL 97 
                    78*******************************9999988777623468888888777777777744443.3333333....68899999.66667 PP

                    -CEE--HHHHHHHHHHHHH...HHTEEETCSEEEECCEECCCCCCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHHHTGG.EEEEEEEEEEEEEE CS
  FAD_binding_3  98 rvtvypqteleriLvehae...erglqvrfktevesleqdeegvtaevrdketgeeetvrakYlvGaDGgrStvrktlgie.fegeetvyeagvld 189
                    + +++p t  +r+++++++   ++g++++++++ + ++    g t  + d +     t +   lv+ DG +S++rk l  + fe     + +++l+
     EEA19340.1  98 HAATFPKTGRLRVIRSKLRtllATGIDIEWSKRCVDITTGSGGATISFEDGT-----TAEGWLLVASDGSNSRIRKYLYPSaFENIP--VAVRLLG 186
                    7788888888888887765333789**********89888888555555554.....466799***************877455544..4799999 PP

                    EEEEC-SCCCTTC....CEEEEECCTTEE........................EEEECCETEEEEEEEEECCE-GGGS....CCCHHHHHHHHHHH CS
  FAD_binding_3 190 vlfdadlsdivep....lvlilsaesrgv........................mviPlentlerfyvqvearaekeer....sekfteeevkarlr 253
                    v+++   +++++      ++ + ++s++                          ++++ +             +k  +    + ++++  +++++ 
     EEA19340.1 187 VTVSYTPEQVASAlaidPYFFQGTHSDSNiylffsflnspyntgndtgnyicqVIVSWAE-------------SK--DiiipESNVERIGLIKNIT 267
                    999998888888899988888889988888999999554443333333333333333333.............22..2323333444444455555 PP

                    HHHTTSSCEE.EEE....EEEEEEEEE.EEESSSEETTEEE-GGGTEEE-STTSHHHHHHHHHHHHHHHHHHHHHTT CS
  FAD_binding_3 254 eivgektldv.eie....evsawtvaq.rvaekyrkgrvflaGDAaHihpPtgGqGlNtaiqDavnLawkLaavlkG 324
                    +   ++  +  ei     e++a ++a+ + ++k +++rv l+GDAaH+++   G G N a+ Da++ a+ ++  ++ 
     EEA19340.1 268 SDWTPHLQKLiEIIpgdaEATAIHLADwFPTTKREHERVVLMGDAAHTMTMFRGEGGNNAVTDAYDFAKRIGPLIEQ 344
                    5555444443333222224556666661556677777*******************************999877664 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.9   0.1   3.9e-09   8.7e-06       1      35 [.      11      49 ..      11      57 .. 0.82

  Alignments for each domain:
  == domain 1  score: 25.9 bits;  conditional E-value: 3.9e-09
                   EE--SHHHHHHHHHHHCCTEEEEEE-SS....SSSSGGG CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekr....drlGGra 35
                   IvGaG+sGl++A++L+k g+   ++++     +r+GG+ 
     EEA19340.1 11 IVGAGISGLSLAQYLRKSGIPFRIFDRDasivSRTGGWG 49
                   9*************************9833334556665 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.1     4e-07   0.00091       2     115 ..       9     127 ..       8     159 .. 0.53

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 4e-07
                 EEEECTSHHHHHHHHHHHHTT..EEEEESSSSTTSSGGGSSEEEEESSSSTHHSTH.............HHHHHHHHHHHHH.HHHHHHHSST.TSEEE CS
         DAO   2 vviiGGGiiGlstAyeLarrg..VtllekgdiagsgaSgrnsgllhsglrylpeas.............elarlslealeel.releeelgid.idyrr 83 
                 ++i+G+Gi Gls A +L + g    +++++  +    +g+ +  +h gl  l+  +              + + +++a +++  +l   + ++   +++
  EEA19340.1   9 ILIVGAGISGLSLAQYLRKSGipFRIFDRDASIV-SRTGGWGLTFHWGLPALK--EllpeelyerlgecNVNPNAQDAGKYRfLDLKTGESLHaATFPK 104
                 89***************7778999****995555.444444444444442222..11233334444443333444444333333333222333233555 PP

                 EEEEEEESSHHHHHHHHHHHHHHHHTTTTEEE CS
         DAO  84 tGllslaadeeelealdkllallleagldael 115
                 tG l + ++     +l+     ll+ g+d e+
  EEA19340.1 105 TGRLRVIRS-----KLRT----LLATGIDIEW 127
                 555555432.....3322....2335666665 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.0   7.5e-06     0.017       3      92 ..       9     139 ..       7     168 .. 0.68

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 7.5e-06
                  EEEE--SHHHHHHHHHHHHHTS-EEEEE...........TTHCHHHCSHHHHCHHHHHHHHHHHHH...............................H CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxx...........xxxxxxxxxxxxxxxxxxxxxxxxxxx...............................x RF
  Pyr_redox_2   3 vvviGgGpAGlaaaltlaqagakvtlve...........legtclnggcllskallgvaedaeias...............................e 58 
                  ++++G+G+ Gl++a++l+++g+   +++            + t+++g + l++ l +   ++  +                                 
   EEA19340.1   9 ILIVGAGISGLSLAQYLRKSGIPFRIFDrdasivsrtggWGLTFHWGLPALKELLPEELYERLGECnvnpnaqdagkyrfldlktgeslhaatfpktG 106
                  78*******************99999965566655555566677777777777666555444322257777777777777777777777777777774 PP

                  HHHCHHHHCCCCHCCTCEEEEESCEEEEETEEEC CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  59 vvkklnqgielllgeevvkidpgkkkvklekkke 92 
                   ++ +++++++ll+ ++++i+  k++v +++ ++
   EEA19340.1 107 RLRVIRSKLRTLLA-TGIDIEWSKRCVDITTGSG 139
                  45556667777777.6666666666776655444 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.0   6.7e-06     0.015      20      65 ..       9      53 ..       3      57 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 6.7e-06
                EEEE--SHHHHHHHHHHHHCTTS-EEEEESSSS--TTTTTTSTTBS CS
        Thi4 20 vvivGaGssGLtaayylakkpdlkvailersvspGGGawlGGqlfs 65
                ++ivGaG sGL+ a+yl k+ ++   i++r  s+   +++ G  f+
  EEA19340.1  9 ILIVGAGISGLSLAQYLRKS-GIPFRIFDRDASIVSRTGGWGLTFH 53
                89****************99.99999**999888777777777775 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   4.5e-05       0.1       2      34 ..       9      41 ..       8      46 .. 0.86
   2 ?   -0.3   0.0      0.72   1.6e+03      51      79 ..     116     146 ..     107     148 .. 0.72

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 4.5e-05
                EEEECSSHHHHHHHHHHHHTTSEEEEEESSSSS CS
   Pyr_redox  2 vvvvGgGyiglElAgalaelgkkVtvversdkl 34
                +++vG+G +gl lA++l++ g    +++r   +
  EEA19340.1  9 ILIVGAGISGLSLAQYLRKSGIPFRIFDRDASI 41
                79*****************99888888887665 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.72
                 HHT...TEEEECSEEEEEEEEETTSEEEEEEE CS
   Pyr_redox  51 ekn...gievllntkveeiegsedgvesvklk 79 
                 + +   gi++ ++++ + i++ + g + + ++
  EEA19340.1 116 RTLlatGIDIEWSKRCVDITTGSGGAT-ISFE 146
                 4444449************98887743.6665 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   4.1e-05     0.092       1      36 [.       9      44 ..       9      63 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 4.1e-05
                EEEES-SHHHHHHHHHHHHTTEEEEEEESSHHHHHH CS
      TrkA_N  1 iiiiGlGrvGrslaeeLseggkdvvvidkdeervee 36
                i+i+G+G  G sla++L+++g+++ + d+d + v +
  EEA19340.1  9 ILIVGAGISGLSLAQYLRKSGIPFRIFDRDASIVSR 44
                79*****************8878*******998866 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   0.0   0.00089         2       3      37 ..      10      44 ..       8      47 .. 0.91
   2 ?    0.9   0.0      0.16   3.6e+02     141     157 ..     272     288 ..     271     311 .. 0.78

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00089
                EEE--SCCHHHHHHHHHHTT-EEEEE-S-HHHHHH CS
     3HCDH_N  3 aviGaGtmGagiaavfasagleVvlvdiseealek 37
                 ++GaG+ G ++a+ + ++g++ +++d++++++ +
  EEA19340.1 10 LIVGAGISGLSLAQYLRKSGIPFRIFDRDASIVSR 44
                69**************************9988765 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.16
                 TTT--EEEEEE-TT--H CS
     3HCDH_N 141 pplmkLvEvvrgekTse 157
                 p+l kL+E+++g++ + 
  EEA19340.1 272 PHLQKLIEIIPGDAEAT 288
                 799********986544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (403 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       513  (0.0286129); expected 358.6 (0.02)
Passed bias filter:                      503  (0.0280551); expected 358.6 (0.02)
Passed Vit filter:                        64  (0.00356964); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 2781.78
//
Query:       EEA19341.1  [L=418]
Description: salicylate hydroxylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (418 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       484  (0.0269954); expected 358.6 (0.02)
Passed bias filter:                      482  (0.0268838); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.42
# Mc/sec: 2988.63
//
Query:       EEA19342.1  [L=483]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.3e-19   67.7  32.4    1.2e-18   67.2  32.4    1.3  1  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.037   13.7   5.5        5.5    6.6   0.8    3.5  3  DUF4131   Domain of unknown function (DUF4131)
       0.11   12.5   0.1       0.18   11.8   0.1    1.3  1  HbrB      HbrB-like


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.2  32.4     2e-22   1.2e-18       2     347 ..      49     418 ..      48     450 .. 0.73

  Alignments for each domain:
  == domain 1  score: 67.2 bits;  conditional E-value: 2e-22
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalga....avaslplGrlsdrfGrrrvlllglllfalglllll..fasslwlllvlrvl 94 
                 l++ +ls ++r+++g+al + l  dl++++  + l++t+  +      + ++l++ +l  +f    +  l+l++ +lgl+ l   f  ++ +ll+ r++
  EEA19342.1  49 LFLNVLSLMGRTNIGAALIQELPADLHLTAMRVFLATTMPLVMLilfeVPSNLLMKWLEAKFNLSYMRYLSLITVCLGLVTLGqaFDKTYSALLATRFV 147
                 78899***************999****9999999999996665511126666666666669966668888888888883333345625555******** PP

       MFS_1  95 qGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg......Wravfyilaivsllafv.lfllllpeepperkrkspke 186
                  G++ ++l+p+++ +++ ++p  +    +++l++++ ++ i+  +l+ ++a+  +      Wr++f++ + ++++ ++ +  +   + +pe++++ ++e
  EEA19342.1 148 IGVFDAGLIPGCVFILSLYYPSIHMQWRMSMLMVANLISNIVSNILAFAIAEIRNqngwhgWRWIFLVEGCLTMVIGLaC--CTSNTGRPEKANFLTQE 244
                 ***************************************************8888999999***************9955..88899999999999999 PP

       MFS_1 187 ee........kgtgpaplvp.....awkallkdp..vlwillialllfffgfsglltllplylqevlgls...glllaglllallalvgailallagrl 267
                 e+        +++      +      w+ ++++   ++w+ l++l +    ++++  + p++ ++v++        + g  +  +++v+a+ +ll+++l
  EEA19342.1 245 EKdiislsveSRVS-----TigyvaEWEVFFSNIlnYVWASLYVLTCS--TTYSVALFAPSF-VKVFKPHlstP-AIQGQ-VVPIFVVSAATCLLVAWL 333
                 97777655553333.....14455577777777721224333333333..556699999998.88888776543.33333.444444445669****** PP

       MFS_1 268 sdrlgrrrrl.llallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdlappeeag.....tasglfntagsl 347
                 +dr+++r +  +++++++++++l+l +  ++ s+v++l +l+++++g     p++++l++ ++ +  +      +++g+ n ag +
  EEA19342.1 334 ADRTNHRSTYaIIGYIFTIIGYLILHFPRHYGSSVMML-GLYFVSIGTYSSLPMVWTLTTLNLATPLQKaigsgFVIGIGNAAGFV 418
                 ***99954430444555566666666666664444444.77888886666778888888888755444422222555555544443 PP

>> DUF4131  Domain of unknown function (DUF4131)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.1     0.016        96      17      77 ..     195     255 ..     153     269 .. 0.74
   2 ?    6.6   0.8   0.00092       5.5       5      53 ..     314     362 ..     310     385 .. 0.65
   3 ?    4.8   0.0    0.0032        19       8      66 ..     407     474 ..     402     481 .. 0.76

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.016
     DUF4131  17 llllllllrrrprrrvllllllllllallgfalrapqpnandlsqlles.gqeviveGvvas 77 
                 ++++ +++++ ++  ++++l   +l++++g+a+ + ++++ +++++l++ ++++i    v+s
  EEA19342.1 195 FAIAEIRNQNGWHGWRWIFLVEGCLTMVIGLACCTSNTGRPEKANFLTQeEKDII-SLSVES 255
                 2233333334899999999999999999999999999999999999986444443.334444 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.00092
     DUF4131   5 lalvllalllllllllllllrr.rprrrvllllllllllallgfalrapq 53 
                  ++v ++++ ++++ll+++l +  ++r + +++++++ +  +++ l+ p+
  EEA19342.1 314 GQVVPIFVVSAATCLLVAWLADrTNHRSTYAIIGYIFTI-IGYLILHFPR 362
                 556666777777777777766635555555555555555.5555555444 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.0032
     DUF4131   8 vllalllllllllllllrrrprrrv........llllllllllallgfalrapqpnandlsqlles.g 66 
                 ++++++ ++ ++ ++++r    + +        +l+++++ l+a+ +++++ +++ +++ s+ +es +
  EEA19342.1 407 FVIGIGNAAGFVSAWIFRTSEAPYYksgmvdglILTCCAAGLTAVTWVYIEWHNRKTSRTSDNIESlS 474
                 5677777777777777755333333668888889***********************99999998763 PP

>> HbrB  HbrB-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.1     3e-05      0.18      83     119 ..     263     299 ..     244     328 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3e-05
        HbrB  83 veiWkffytqvlpyleavfLPLetefklssllaeske 119
                 v  W++f++++l y+ a++  L+++++ s +l++++ 
  EEA19342.1 263 VAEWEVFFSNILNYVWASLYVLTCSTTYSVALFAPSF 299
                 678*********************9998888877765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (483 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       760  (0.0423894); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.56u 0.25s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 3194.99
//
Query:       EEA19343.1  [L=373]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.048   14.1   1.0       0.11   13.0   1.0    1.6  1  SCIMP     SCIMP protein
       0.66    9.8   5.0          2    8.3   0.3    3.0  3  DUF5337   Family of unknown function (DUF5337)


Domain annotation for each model (and alignments):
>> SCIMP  SCIMP protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   1.0   1.2e-05      0.11       5      45 ..      60     100 ..      56     120 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 1.2e-05
       SCIMP   5 rdnfWiilavaiivvsvvlglilycvcrrllrqGkkweiak 45 
                 +  fWi+l+   +v+s ++++ l  vc +l++ G+  + a+
  EEA19343.1  60 ESRFWILLSDIAVVISYSIAVALTAVCYVLVHWGEGIHTAE 100
                 468***************************99998877665 PP

>> DUF5337  Family of unknown function (DUF5337)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.5      0.02   1.8e+02      17      48 ..      77     112 ..      70     117 .. 0.74
   2 ?    8.3   0.3   0.00022         2      15      69 ..     176     232 ..     174     237 .. 0.89
   3 ?   -1.7   0.0      0.29   2.6e+03      47      62 ..     253     268 ..     251     270 .. 0.79

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.02
     DUF5337  17 alviavtmllwlgaqw....igeqlglsnRyalLfd 48 
                 ++++a t++ ++++ w      ++l +++R+++L+ 
  EEA19343.1  77 SIAVALTAVCYVLVHWgegiHTAELSITQRHMVLMM 112
                 688999999999999843323456777778777765 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.00022
     DUF5337  15 lvalviavtmllwlgaqwigeqlglsnRy..alLfdLaAlAaliwalvvtyqlwraR 69 
                 ++a+   +tm++ ++  w+ + +    +y  a+++ L A +  + + v +y l r  
  EEA19343.1 176 HAAINTSATMVMVVLPWWLFSSIQYRHKYliAVIMGLLAVGETVLGAVRIYGLCRSS 232
                 6788899*********************9556799******************9975 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 0.29
     DUF5337  47 fdLaAlAaliwalvvt 62 
                 +d+a +Aa +  +++t
  EEA19343.1 253 VDFACIAACVPTVLKT 268
                 69******88766666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (373 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       741  (0.0413297); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.30s 00:00:00.83 Elapsed: 00:00:00.50
# Mc/sec: 2258.99
//
Query:       EEA19344.1  [L=396]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.044   14.3   1.0       0.12   12.9   1.0    1.8  1  SCIMP     SCIMP protein
       0.53   10.2   4.6        2.2    8.2   0.3    3.1  3  DUF5337   Family of unknown function (DUF5337)


Domain annotation for each model (and alignments):
>> SCIMP  SCIMP protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   1.0   1.3e-05      0.12       5      45 ..      60     100 ..      56     119 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.3e-05
       SCIMP   5 rdnfWiilavaiivvsvvlglilycvcrrllrqGkkweiak 45 
                 +  fWi+l+   +v+s ++++ l  vc +l++ G+  + a+
  EEA19344.1  60 ESRFWILLSDIAVVISYSIAVALTAVCYVLVHWGEGIHTAE 100
                 468***************************99998877665 PP

>> DUF5337  Family of unknown function (DUF5337)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.5     0.021   1.9e+02      17      48 ..      77     112 ..      70     117 .. 0.74
   2 ?    8.2   0.3   0.00025       2.2      15      69 ..     199     255 ..     197     260 .. 0.89
   3 ?   -1.9   0.0      0.34     3e+03      47      62 ..     276     291 ..     275     293 .. 0.79

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.021
     DUF5337  17 alviavtmllwlgaqw....igeqlglsnRyalLfd 48 
                 ++++a t++ ++++ w      ++l +++R+++L+ 
  EEA19344.1  77 SIAVALTAVCYVLVHWgegiHTAELSITQRHMVLMM 112
                 688999999999999843323456777778777765 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.00025
     DUF5337  15 lvalviavtmllwlgaqwigeqlglsnRy..alLfdLaAlAaliwalvvtyqlwraR 69 
                 ++a+   +tm++ ++  w+ + +    +y  a+++ L A +  + + v +y l r  
  EEA19344.1 199 HAAINTSATMVMVVLPWWLFSSIQYRHKYliAVIMGLLAVGETVLGAVRIYGLCRSS 255
                 6788899*********************9556799******************9975 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 0.34
     DUF5337  47 fdLaAlAaliwalvvt 62 
                 +d+a +Aa +  +++t
  EEA19344.1 276 VDFACIAACVPTVLKT 291
                 59******88766666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (396 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       900  (0.050198); expected 358.6 (0.02)
Passed bias filter:                      360  (0.0200792); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.22s 00:00:00.69 Elapsed: 00:00:00.38
# Mc/sec: 3097.12
//
Query:       EEA19345.1  [L=358]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
     0.0049   16.3   0.0     0.0071   15.8   0.0    1.2  1  adh_short  short chain dehydrogenase
  ------ inclusion threshold ------
        1.2    9.2   4.2        1.7    8.7   0.1    3.1  3  DUF1658    Protein of unknown function (DUF1658)


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   7.9e-07    0.0071       2      84 ..      21     119 ..      20     173 .. 0.70

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 7.9e-07
                 EEEEESTTSHHHHHHHHHHHH......TT-EEEEEESCHHHHHHHHHHHHHT..TSEEEEE.E-TTTSHHHHHHHHHHHHHHH.......SSESEEEE- CS
   adh_short   2 vvlvtGassGIGraiakelak......eGakvvvvdrseekleevakelkee..gakalai.qvDvtdreevealvekavkkl.......gkldvLvnN 84 
                 +++ +G++sGIG    ++la+       G +v++v+r+e++++++++ + +   + +++++ + D+++ +ev+++ +++++          ++d+Lv  
  EEA19345.1  21 TAVFVGGTSGIGEYSLRALASvhghsgHGLRVYIVGRNEKAANTIISDCLKVcpAGTFHFVrASDLASLREVDRICKEIINAEgasagksASIDLLVMS 119
                 58899*******988888876444444799*******************999997777777256************99987543333333456666655 PP

>> DUF1658  Protein of unknown function (DUF1658)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.2      0.23   2.1e+03      14      21 .]      43      50 ..      29      50 .. 0.88
   2 ?    8.7   0.1   0.00019       1.7       5      13 ..     276     284 ..     275     305 .. 0.86
   3 ?   -0.6   0.0      0.17   1.5e+03      15      20 ..     351     356 ..     351     357 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.23
     DUF1658 14 HGrdGrgi 21
                HG  G+g+
  EEA19345.1 43 HGHSGHGL 50
                9*9***95 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.00019
     DUF1658   5 TrriPARPs 13 
                 ++r+PARPs
  EEA19345.1 276 SPRFPARPS 284
                 89******9 PP

  == domain 3  score: -0.6 bits;  conditional E-value: 0.17
     DUF1658  15 GrdGrg 20 
                 ++dG++
  EEA19345.1 351 SNDGHF 356
                 79***9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (358 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       277  (0.0154498); expected 358.6 (0.02)
Passed bias filter:                      270  (0.0150594); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 2456.56
//
Query:       EEA19346.1  [L=394]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.5e-06   26.2  10.7    1.3e-05   25.2  10.7    1.5  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2  10.7   7.2e-10   1.3e-05       2      36 ..      26      59 ..      25      62 .. 0.93

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 7.2e-10
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfyses 36
                +C nC+ ++vKCd++ P+C +C+ +++ C  y+ +
  EEA19346.1 26 GCANCKLRRVKCDEGMPECCECQAYGVCCN-YDIR 59
                6****************************9.9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (394 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       525  (0.0292822); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 2576.13
//
Query:       EEA19347.1  [L=109]
Description: hypothetical protein PMAA_001420 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (109 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       304  (0.0169558); expected 358.6 (0.02)
Passed bias filter:                      264  (0.0147247); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.27s 00:00:00.67 Elapsed: 00:00:00.44
# Mc/sec: 745.36
//
Query:       EEA19348.1  [L=598]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.9e-10   40.1   2.6    3.9e-10   39.1   0.5    2.0  2  Fungal_trans_2  Fungal specific transcription factor domain
    0.00059   19.9   2.3     0.0015   18.6   2.3    1.6  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.017   15.1   1.1      0.097   12.7   0.1    2.4  2  efb-c           Extracellular fibrinogen binding protein C te


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.1   0.5   6.6e-14   3.9e-10      10     149 ..     100     237 ..      93     282 .. 0.76
   2 ?    0.8   0.1     0.029   1.7e+02     246     294 ..     307     352 ..     293     372 .. 0.80

  Alignments for each domain:
  == domain 1  score: 39.1 bits;  conditional E-value: 6.6e-14
  Fungal_trans_2  10 vapllspvpessnpfrkvllplalsnkallhallalsafhl..qskgpkdslereakryksl.alkelqealaelsstls..rnekykdiLaaiL 99 
                     ++p +s + ++   +++++lp+ +s++a+ ha++al+a+h   +++g + s + e ++++++ al++  +al+ lss+    +++    +L+++L
      EEA19348.1 100 TVPKMSSFFDT-HLWHNLVLPMSHSERAVTHAVIALGALHEdiEARGVPLS-RAELTNHRQRfALEQYTRALSLLSSHRHvnDPKLRGVVLTCCL 192
                     67888888887.99***************************7744444443.88888999889*****************95555555666667* PP

  Fungal_trans_2 100 llcsieissgdvsdwrvhLeaatsliksrggskasssslsskarfllrif 149
                     l +++e   g  ++  vhL++  sl+k  ++      + ++  ++ l+  
      EEA19348.1 193 LFVMFELLRGLYDEAFVHLQQGLSLVKAFKEV-----DTQPQSPLVLESS 237
                     ***********99**************99999.....4444444444444 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.029
  Fungal_trans_2 246 epdldeterasslskdltelfrlaaliylyrlvlglppsspevqelvkk 294
                     ++++++++++++l+    + ++++++i l r++++l++ ++++q+++++
      EEA19348.1 307 SEPRPPDSNITRLD---VTRMQVCLRIELARYLHRLNRFESRMQKSLDR 352
                     55667777777777...67799**********************99976 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   2.3   2.5e-07    0.0015       8      36 ..      19      47 ..      18      49 .. 0.88

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 2.5e-07
                HCT---STSSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus  8 kkKvKCdakkPaCsnCkklnleCtfyses 36
                +++vKCd+   aC+nC + +++C  y+e 
  EEA19348.1 19 RRHVKCDETPIACKNCHSAGWKCDGYDEN 47
                79*****97667***********999875 PP

>> efb-c  Extracellular fibrinogen binding protein C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.1   1.6e-05     0.097      19      56 ..     340     377 ..     336     379 .. 0.87
   2 ?   -0.4   0.1       0.2   1.2e+03      19      33 ..     478     492 ..     473     497 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 1.6e-05
       efb-c  19 reFkktrtvaaHRkAqkAvnLvsFeykvkkkkLqeriD 56 
                 + F+     +  Rk q+A++L+  ++k    +L   iD
  EEA19348.1 340 NRFESRMQKSLDRKSQRAIDLIRLHHKTFSLVLETYID 377
                 667777777889****************9999999998 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.2
       efb-c  19 reFkktrtvaaHRkA 33 
                  eFk+  t+ + Rk 
  EEA19348.1 478 AEFKRLSTIKTIRKT 492
                 58***********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (598 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       535  (0.0298399); expected 358.6 (0.02)
Passed bias filter:                      447  (0.0249317); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.63u 0.31s 00:00:00.94 Elapsed: 00:00:00.48
# Mc/sec: 3727.54
//
Query:       EEA19349.1  [L=549]
Description: C6 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.3e-05   23.5  13.6    7.5e-05   22.8  13.6    1.4  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.016   14.1   0.1      0.039   12.8   0.0    1.7  2  Fungal_trans_2  Fungal specific transcription factor domain
       0.24   11.5   0.7       0.49   10.5   0.0    1.8  2  Vps51           Vps51/Vps67


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8  13.6   1.3e-08   7.5e-05       2      36 ..      29      63 ..      28      67 .. 0.91

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 1.3e-08
                S-HHHHHCT---STSSSS-HHHHHCT..HHHCCCCTC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkkln..leCtfyses 36
                +C +C k+KvKCd+ kP C+ C  ++  +eC+ y+  
  EEA19349.1 29 SCLSCQKRKVKCDRVKP-CRACCIRGvpAECE-YDTT 63
                8****************.********9*****.7754 PP

>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0      0.51   3.1e+03     282     307 ..      70      95 ..      57      98 .. 0.64
   2 ?   12.8   0.0   6.5e-06     0.039      59     140 ..     206     282 ..     159     329 .. 0.75

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 0.51
  Fungal_trans_2 282 ppsspevqelvkkllellellpsspv 307
                       +s++++el +k+ +l ++l+++++
      EEA19349.1  70 IEQSDLIEELRAKVKKLEQKLSEHNG 95 
                     44566666666666666666666655 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 6.5e-06
  Fungal_trans_2  59 lereakrykslalkelqealaelsstlsrnekykdiLaaiLllcsieissgd.vsdwrvhLeaatsliksrggskasssslss 140
                       +  ++ + +al++lq+   ++++++s     +d L+++ ll +ie ++ + ++    h  +  +l++ r +  +++++l++
      EEA19349.1 206 FLTAGNNQYHRALRLLQKTVDDPQQCTS-----TDALTMVVLLTVIEAFNQSsPGAIFKHQLGGLELLRLRTPY-RHRTGLDQ 282
                     4677889999******************.....**************887773454777999999999988887.33333333 PP

>> Vps51  Vps51/Vps67
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   8.2e-05      0.49      53      83 ..      69      99 ..      65     102 .. 0.90
   2 ?   -3.7   0.1       2.2   1.3e+04      22      43 ..     357     378 ..     353     378 .. 0.69

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 8.2e-05
       Vps51 53 LisasdtIrkmksemdkldqklselkqaisk 83
                +i+ sd I++++ +++kl+qklse +  +sk
  EEA19349.1 69 FIEQSDLIEELRAKVKKLEQKLSEHNGIVSK 99
                9**********************99887776 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 2.2
       Vps51  22 kellkveasllseiraldselk 43 
                 +el + +++++  +++ld+ l+
  EEA19349.1 357 SELVAAQNDIQFTATTLDQRLR 378
                 5777777777777777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (549 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       723  (0.0403257); expected 358.6 (0.02)
Passed bias filter:                      509  (0.0283898); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.41
# Mc/sec: 4021.46
//
Query:       EEA19350.1  [L=594]
Description: hypothetical protein PMAA_001450 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (594 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1139  (0.0635284); expected 358.6 (0.02)
Passed bias filter:                      400  (0.0223102); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.57u 0.32s 00:00:00.88 Elapsed: 00:00:00.45
# Mc/sec: 3988.96
//
Query:       EEA19351.1  [L=143]
Description: hypothetical protein PMAA_001460 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-10   41.9   0.6    1.4e-10   41.5   0.6    1.3  1  PBP       Phosphatidylethanolamine-binding protein


Domain annotation for each model (and alignments):
>> PBP  Phosphatidylethanolamine-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.5   0.6   8.1e-15   1.4e-10      21      90 ..      77     143 .]      35     143 .] 0.74

  Alignments for each domain:
  == domain 1  score: 41.5 bits;  conditional E-value: 8.1e-15
                 -TTSSEEEEEEEETTSCCTCT..TEEEEEEEEEETTSSEE-TTCEE-B-TTSSCCCCS---B--STTS..EE CS
         PBP  21 pegtksyalvviDpDapkvse..tflHwvvtnipasvtslpegavqgknslgeesesgYlgpcPpkgdgkHr 90 
                    t++y++++iD+D+p++++  +flHw++ +++ ++++   g+ ++ +s++   +++Y++p+Pp+g  +Hr
  EEA19351.1  77 STFTSHYIIFMIDLDVPQNDTivPFLHWYQPDLSLDHKT---GKLSIPKSSHL-AKAEYYPPSPPPGP-EHR 143
                 33499************8888744**********77777...33333344444.667**********9.597 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (143 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       271  (0.0151152); expected 358.6 (0.02)
Passed bias filter:                      238  (0.0132746); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.37u 0.25s 00:00:00.62 Elapsed: 00:00:00.40
# Mc/sec: 1065.92
//
Query:       EEA19352.1  [L=396]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.91    9.2   6.0       0.67    9.6   2.4    2.3  2  LUD_dom   LUD domain


Domain annotation for each model (and alignments):
>> LUD_dom  LUD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.1     0.038   6.8e+02      91     114 ..      23      46 ..      10      59 .. 0.84
   2 ?    9.6   2.4   3.7e-05      0.67      51     123 ..     119     194 ..      63     233 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.038
     LUD_dom  91 ganfaiAetGtlvlvdnegnrral 114
                   n ai+  G l++  ++g++++l
  EEA19352.1  23 QGNGAITAIGALTNLGQPGQAATL 46 
                 5799***************99766 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 3.7e-05
     LUD_dom  51 l....apalhsgreevldlfeekltreareelrekfltadvgitganfaiAetGtlvlvdnegnrraltflpkvhiv 123
                 +    +pa+  ++ e ++  + k+t+++   l      +  g++ +  a+A++Gt v  +  gn++a  ++ ++  +
  EEA19352.1 119 VvpliDPAVTGQNVENANSATSKVTPFDATGLSVAQVMVAHGFSNFT-AVAQDGTKVAASKLGNGAAAGTGTETATA 194
                 3666689999999999*******************************.*****************999888877655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (396 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1121  (0.0625244); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.44
# Mc/sec: 2686.34
//
Query:       EEA19353.1  [L=396]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.037   14.2   1.0      0.071   13.2   1.0    1.4  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   1.0     4e-06     0.071      16      35 ..      10      28 ..       7      33 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 4e-06
                SSSS-HHHHHCTHHHCCCCT CS
     Zn_clus 16 kkPaCsnCkklnleCtfyse 35
                + P+C +Ck+++ eC+ ++ 
  EEA19353.1 10 QAPQCHHCKRRGEECS-FQL 28
                78*************9.554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (396 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       868  (0.0484132); expected 358.6 (0.02)
Passed bias filter:                      577  (0.0321825); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.46
# Mc/sec: 2594.29
//
Query:       EEA19354.1  [L=251]
Description: ribulose-phosphate 3-epimerase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.4e-61  206.1   0.0    4.5e-60  202.4   0.0    2.0  1  Ribul_P_3_epim  Ribulose-phosphate 3 epimerase family
  ------ inclusion threshold ------
      0.043   13.4   0.0      0.067   12.8   0.0    1.4  1  OMPdecase       Orotidine 5'-phosphate decarboxylase / HUMPS 
      0.052   12.8   0.1      0.072   12.4   0.1    1.2  1  ThiG            Thiazole biosynthesis protein ThiG


Domain annotation for each model (and alignments):
>> Ribul_P_3_epim  Ribulose-phosphate 3 epimerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  202.4   0.0   7.6e-64   4.5e-60       2     198 .]       7     230 ..       6     230 .. 0.90

  Alignments for each domain:
  == domain 1  score: 202.4 bits;  conditional E-value: 7.6e-64
                     EEEBGGGS-GGGHHHHHHHHHHTT-SEEEEEEEBSSSSS-B-B-HHHHHHHGGG........E-S-EEEEEESSSHHHCHHHHHHCT-SEEEEE- CS
  Ribul_P_3_epim   2 iapSllsadfarlgeevkaveeagadllHvDvmDghfvpNltigplvvealrkl........telpldvHLmveevdrivpefaeagasiisvHa 88 
                     iapS+lsadfa+lg e ++  e gad+lHvD+mDghfvpN+t+g  vv ++r++        +   +d+H+m++e++++v ef +ag ++ ++H+
      EEA19354.1   7 IAPSILSADFAQLGPECATTMERGADWLHVDIMDGHFVPNMTFGAPVVTKIRSHvakpatpgERGTFDCHMMIAEPQKWVSEFKSAGCDLYCFHY 101
                     9***************************************************997776666556689**************************** PP

                     S.................T-TTHHHHHHHHHHTTSEEEEEE-TT--GGGGTTTCCC......-SEEEEESS-TT-SS----CCHHHHHHHHHHHH CS
  Ribul_P_3_epim  89 E.................alehlkrtiqeikeaGakaglvlnpatplealeyllek......ldlvllmsvePgfgGQkFipevlekikkvrkli 160
                     E                 + + +k++i+ i+e G+kag++++p t +++l ++le+       d+vl+m+v PgfgGQkF+ + l+k+ ++r+++
      EEA19354.1 102 EaaisstaakdpadytttTKTSPKELIRYIHESGMKAGIAIKPDTKVDVLWDILENeteierPDMVLVMTVHPGFGGQKFMASELPKVTALRQRY 196
                     *9888777666665544334568999***********************999986422222269******************************* PP

                     HHHT---EEEEESS--TTTCHHHHHHT--EEEESHHHH CS
  Ribul_P_3_epim 161 dekeldlkievDGGvkldnieqiaeagadvlVagsavf 198
                     ++    l+ievDGG+ l +i+q+a+aga+v+Vagsavf
      EEA19354.1 197 PN----LNIEVDGGLGLGTIDQAADAGANVIVAGSAVF 230
                     *8....*******************************9 PP

>> OMPdecase  Orotidine 5'-phosphate decarboxylase / HUMPS family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   1.1e-05     0.067     184     224 ..     202     241 ..     152     242 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.1e-05
                 EECTTCCGGGHHHHHHHTTCSEEEESHHHHTSSSHHHHHHH CS
   OMPdecase 184 gdgkgqqyntpekligiagadiiivGRgIlkagdpveeaer 224
                 ++ +g+   t++++++ aga++i++G ++++a+dp+e +++
  EEA19354.1 202 EVDGGLGLGTIDQAAD-AGANVIVAGSAVFGAKDPAEVIQK 241
                 5667777778888877.99*****************98876 PP

>> ThiG  Thiazole biosynthesis protein ThiG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   1.2e-05     0.072     167     226 ..     189     248 ..     167     251 .] 0.85

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 1.2e-05
                 HHHHHHH-.SS-BEEES---SHHHHHHHHHTT-SEEEESHHHHTSSSHHHHHHHHHHHHHH CS
        ThiG 167 lkiiieea.kvPvivDAGigspsdaaqamelGadavllntavaeakdpvamArafklavea 226
                 ++ ++++  ++ + vD G+g    + qa + Ga+ ++  +av  akdp+++ + ++ ave 
  EEA19354.1 189 VTALRQRYpNLNIEVDGGLGLG-TIDQAADAGANVIVAGSAVFGAKDPAEVIQKLRDAVEK 248
                 55666776678899***99986.57889999**************************9985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (251 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       474  (0.0264376); expected 358.6 (0.02)
Passed bias filter:                      448  (0.0249875); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 1657.15
//
Query:       EEA19355.1  [L=384]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.2e-05   22.5   1.3    0.00026   21.1   0.0    2.5  2  SH3BGR          SH3-binding, glutamic acid-rich protein


Domain annotation for each model (and alignments):
>> SH3BGR  SH3-binding, glutamic acid-rich protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.1   0.0   1.5e-08   0.00026       3      49 ..       6      52 ..       4      86 .. 0.86
   2 ?   -3.2   1.8      0.55   9.8e+03      48      53 ..     347     352 ..     324     375 .. 0.51

  Alignments for each domain:
  == domain 1  score: 21.1 bits;  conditional E-value: 1.5e-08
                EEEEE-SS-SSHHHHHHHHHHHHHHHHTT--EEEEETTT-HHHHHHH CS
      SH3BGR  3 lkvyvasssgskeikkkqqevlriLdakkiefdevDitkdeeerelm 49
                l  y + ++gs  i    ++  +iL a+ki+f+ +Di++d++ r+l 
  EEA19355.1  6 LYLYTSLTAGSSHIITATSRLETILKANKIPFQAIDIATDDAARRLW 52
                667999999******************************88888764 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 0.55
                 HHHHCS CS
      SH3BGR  48 lmrena 53 
                 + +e+ 
  EEA19355.1 347 EKKEDK 352
                 222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (384 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2174  (0.121256); expected 358.6 (0.02)
Passed bias filter:                      773  (0.0431145); expected 358.6 (0.02)
Passed Vit filter:                       191  (0.0106531); expected 17.9 (0.001)
Passed Fwd filter:                        52  (0.00290033); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.92u 0.33s 00:00:01.25 Elapsed: 00:00:00.49
# Mc/sec: 2336.50
//
Query:       EEA19356.1  [L=237]
Description: hypothetical protein PMAA_001510 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.1e-09   36.3  24.4    5.1e-09   36.3  24.4    5.3  4  CYSTM     Cysteine-rich TM module stress tolerance


Domain annotation for each model (and alignments):
>> CYSTM  Cysteine-rich TM module stress tolerance
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?  -18.4  26.9         1   1.8e+04       1      11 [.      26      36 ..       3      45 .. 0.63
   2 !   36.3  24.4   2.9e-13   5.1e-09       1      42 []      45      89 ..      40      89 .. 0.84
   3 ?  -10.2  12.2         1   1.8e+04      34      42 .]      91      99 ..      88      99 .. 0.52
   4 ?   -2.7   2.0      0.42   7.6e+03      15      19 ..     136     140 ..     124     171 .. 0.63

  Alignments for each domain:
  == domain 1  score: -18.4 bits;  conditional E-value: 1
       CYSTM  1 ppqpgYyqqpp 11
                ppq gYy++++
  EEA19356.1 26 PPQGGYYPPQQ 36
                45555555433 PP

  == domain 2  score: 36.3 bits;  conditional E-value: 2.9e-13
       CYSTM  1 ppqpgYyqqppvqe.qppqkgdg..GclagClaALcCCclcdecf 42
                +p++gY q+pp+q+ q+ q+g++  Gcl++Cla+LcCC+lc+e +
  EEA19356.1 45 YPPQGYQQPPPPQQyQQEQRGGRdhGCLGACLATLCCCFLCEESC 89
                58889988888888977777666678****************987 PP

  == domain 3  score: -10.2 bits;  conditional E-value: 1
       CYSTM 34 CCclcdecf 42
                CC+ c ec+
  EEA19356.1 91 CCFDCIECC 99
                555555555 PP

  == domain 4  score: -2.7 bits;  conditional E-value: 0.42
       CYSTM  15 qppqk 19 
                 q++ k
  EEA19356.1 136 QTKMK 140
                 54443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (237 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       883  (0.0492498); expected 358.6 (0.02)
Passed bias filter:                      245  (0.013665); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 1670.46
//
Query:       EEA19357.1  [L=566]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
      0.019   15.0   3.5       0.73    9.9   0.1    2.6  2  zf-BED     BED zinc finger
        9.7    7.3   6.6        5.4    8.1   2.3    2.7  2  zf-C2H2_4  C2H2-type zinc finger


Domain annotation for each model (and alignments):
>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.1   8.2e-05      0.73       8      44 .]     361     395 ..     360     395 .. 0.89
   2 ?    5.3   0.5    0.0022        20       2      43 ..     399     439 ..     398     440 .. 0.89

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 8.2e-05
                 ----GGSS--EETTTTEE----SSTHHHHHHHHHS-H CS
      zf-BED   8 tpvslkeqkavCryCgkilsrgggttnLkrHLrrkHp 44 
                 ++++  + k++C  C  +  + +g + L+rH++r H+
  EEA19357.1 361 QRPP--RPKTYCHLCSDQPEGFHGEHELRRHIERVHS 395
                 5566..7799**************************6 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0022
                 -TTSSS----GGSS--EETTTTEE----SSTHHHHHHHHHS- CS
      zf-BED   2 kvWkyftpvslkeqkavCryCgkilsrgggttnLkrHLrrkH 43 
                 kvW  +++ + k   a C+ C +   +g    n  +HLrr H
  EEA19357.1 399 KVWVCVDISPDKTFLANCKACRNGKRYG-ANYNAAAHLRRTH 439
                 688888899988999*******999998.88999******99 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   2.3   0.00061       5.4       2      24 .]     369     394 ..     368     394 .. 0.95
   2 ?   -0.3   0.1      0.32   2.8e+03       3      24 .]     416     439 ..     415     439 .. 0.73

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00061
   zf-C2H2_4   2 kCpiC...gksFsskkaLlrHlkthH 24 
                 +C++C   ++ F+  ++L+rH++++H
  EEA19357.1 369 YCHLCsdqPEGFHGEHELRRHIERVH 394
                 7***********************99 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.32
   zf-C2H2_4   3 CpiC..gksFsskkaLlrHlkthH 24 
                 C+ C  gk++  +++   Hl++ H
  EEA19357.1 416 CKACrnGKRYGANYNAAAHLRRTH 439
                 999988899884444477888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (566 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       741  (0.0413297); expected 358.6 (0.02)
Passed bias filter:                      343  (0.019131); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.25s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3991.48
//
Query:       EEA19358.1  [L=691]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      4e-06   27.0  20.1       0.16   12.5   2.5    4.7  4  zf-C2H2      Zinc finger, C2H2 type
    1.2e-05   25.7  22.1    0.00078   20.1   2.4    4.7  4  zf-C2H2_4    C2H2-type zinc finger
    0.00065   19.5   0.6     0.0024   17.7   0.6    2.0  1  Homeodomain  Homeodomain
     0.0019   18.1   1.3     0.0034   17.3   0.6    1.9  2  Homeobox_KN  Homeobox KN domain
     0.0041   17.1   0.0      0.011   15.7   0.0    1.8  1  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
      0.038   13.5   0.4       0.19   11.2   0.4    2.1  1  Homez        Homeodomain leucine-zipper encoding, Homez
       0.06   13.7   0.4       0.27   11.6   0.1    2.2  2  HA           Helicase associated domain
        2.7    8.5   5.6        3.4    8.2   0.0    3.4  3  zf-met       Zinc-finger of C2H2 type
        3.9    7.9   9.2         26    5.2   0.0    4.2  4  zf-C2H2_2    C2H2 type zinc-finger (2 copies)


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.5   2.5   7.9e-05      0.16       1      23 []     386     409 ..     386     409 .. 0.96
   2 !    8.4   1.4    0.0016       3.2       2      20 ..     433     451 ..     433     453 .. 0.94
   3 !    9.0   0.2     0.001         2       8      23 .]     463     479 ..     455     479 .. 0.88
   4 !    7.3   0.1    0.0035         7       2      23 .]     500     521 ..     499     521 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 7.9e-05
                 EEETTTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirt.H 23 
                 ++C+ C+ sFk+k++  rH ++ H
  EEA19358.1 386 FQCTFCTDSFKTKYDWSRHEKSlH 409
                 89*****************99988 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0016
                 EETTTTEEESSHHHHHHHH CS
     zf-C2H2   2 kCpdCgksFkrksnLkrHi 20 
                 kC +C+ s ++ ++L +H+
  EEA19358.1 433 KCAYCNTSSPTEEHLHTHR 451
                 7*****************6 PP

  == domain 3  score: 9.0 bits;  conditional E-value: 0.001
                 EEESSHHHHHHHHHC.C CS
     zf-C2H2   8 ksFkrksnLkrHirt.H 23 
                 +++ rk++L++H+r  H
  EEA19358.1 463 RTYYRKDHLRQHLRLvH 479
                 899***********999 PP

  == domain 4  score: 7.3 bits;  conditional E-value: 0.0035
                 EETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   2 kCpdCgksFkrksnLkrHirtH 23 
                 +C+ C+k+ +++     H+  H
  EEA19358.1 500 RCGFCDKVLTTWQARIDHLAAH 521
                 7************999999877 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   2.4   3.9e-07   0.00078       1      24 []     386     409 ..     386     409 .. 0.97
   2 !    6.4   1.0    0.0096        19       2      20 ..     433     451 ..     432     453 .. 0.93
   3 ?    3.7   0.9     0.072   1.4e+02       8      24 .]     463     479 ..     462     479 .. 0.85
   4 !    7.5   0.1    0.0043       8.6       2      23 ..     500     521 ..     499     522 .. 0.93

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 3.9e-07
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlkthH 24 
                 f+C++C+ sF++k++++rH k+ H
  EEA19358.1 386 FQCTFCTDSFKTKYDWSRHEKSLH 409
                 89*******************998 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.0096
   zf-C2H2_4   2 kCpiCgksFsskkaLlrHl 20 
                 kC +C++s ++ ++L +H 
  EEA19358.1 433 KCAYCNTSSPTEEHLHTHR 451
                 8***************995 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.072
   zf-C2H2_4   8 ksFsskkaLlrHlkthH 24 
                 +++ +k++L++Hl+ +H
  EEA19358.1 463 RTYYRKDHLRQHLRLVH 479
                 56778999******999 PP

  == domain 4  score: 7.5 bits;  conditional E-value: 0.0043
   zf-C2H2_4   2 kCpiCgksFsskkaLlrHlkth 23 
                 +C +C+k+ ++++a  +Hl++h
  EEA19358.1 500 RCGFCDKVLTTWQARIDHLAAH 521
                 6*************888**999 PP

>> Homeodomain  Homeodomain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.6   1.2e-06    0.0024       8      54 ..     154     203 ..     149     204 .. 0.76

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 1.2e-06
                  -HHHHHHHHHHHHH...SSS-SHHHHHHHHHHHTS-HHHHHHHHHHHHHH CS
  Homeodomain   8 tkeqleeLeklFee...nrypsaeereeLAkklgLeerqVkvWFqNrRak 54 
                  tk+ l++L++  ++     +p+ +++ +L ++++L+ +q+ +WF   + +
   EEA19358.1 154 TKQSLRALKDWKAQhgdATKPTMQQIHRLQRRTNLSSEQILNWFSHTKRR 203
                  66666666544332222789************************987755 PP

>> Homeobox_KN  Homeobox KN domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.6   1.7e-06    0.0034      11      40 .]     174     203 ..     150     203 .. 0.89
   2 ?   -3.8   0.0       6.7   1.3e+04      22      33 ..     500     511 ..     499     511 .. 0.90

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 1.7e-06
  Homeobox_KN  11 PseedKeeLlkeTglsvkqitnWFINaRrR 40 
                  P+ ++  +L ++T+ls +qi nWF  + rR
   EEA19358.1 174 PTMQQIHRLQRRTNLSSEQILNWFSHTKRR 203
                  8888889*****************877776 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 6.7
  Homeobox_KN  22 eTglsvkqitnW 33 
                  ++g++ k +t+W
   EEA19358.1 500 RCGFCDKVLTTW 511
                  79999999***9 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   5.6e-06     0.011       5      64 ..     626     686 ..     622     688 .. 0.90

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 5.6e-06
                  HHHHHHHHHHH.C-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHTS--X CS
  HTH_Tnp_Tc5   5 EkaLleWirql.rergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRhglkr 64 
                  E +L+ +i+   + +g+ ++++ i+++ +++  +++d+++++   +  Wl+ Fk+Rhg++ 
   EEA19358.1 626 ETQLATYINTViATEGRIPSDKEIQDQGRRFVFDDDDPWHQTIAENVMWLEYFKERHGFFV 686
                  78899999999999****************985558999999999999*********9875 PP

>> Homez  Homeodomain leucine-zipper encoding, Homez
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.4   9.8e-05      0.19      29      50 ..     179     200 ..     150     205 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 9.8e-05
       Homez  29 ldkLckksklsaqqVrdWFask 50 
                 +  L +++ ls +q+++WF + 
  EEA19358.1 179 IHRLQRRTNLSSEQILNWFSHT 200
                 67899**************996 PP

>> HA  Helicase associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.1   0.00013      0.27       7      44 ..     156     203 ..     155     221 .. 0.82
   2 ?   -2.5   0.0       3.5   6.9e+03       4      15 ..     510     521 ..     509     528 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00013
          HA   7 erleeLkeykaehGhlnvP..........ekteenpsLgkWvakqRqq 44 
                 + l++Lk++ka+hG++  P          +++ +  ++ +W ++ +++
  EEA19358.1 156 QSLRALKDWKAQHGDATKPtmqqihrlqrRTNLSSEQILNWFSHTKRR 203
                 6799***************99999888875566777888888777665 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 3.5
          HA   4 dWeerleeLkey 15 
                 +W++r+++L + 
  EEA19358.1 510 TWQARIDHLAAH 521
                 799999999875 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.7       2.1   4.2e+03       1      22 [.     386     407 ..     386     407 .. 0.80
   2 ?    1.2   0.1      0.27   5.5e+02       8      21 ..     463     476 ..     462     476 .. 0.88
   3 ?    8.2   0.0    0.0017       3.4       3      21 ..     501     519 ..     499     521 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 2.1
      zf-met   1 fyCelCnvtfnsesqlksHlqG 22 
                 f+C  C  +f+ + ++  H ++
  EEA19358.1 386 FQCTFCTDSFKTKYDWSRHEKS 407
                 6788887789999999999876 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.27
      zf-met   8 vtfnsesqlksHlq 21 
                 +t++ + +l++Hl+
  EEA19358.1 463 RTYYRKDHLRQHLR 476
                 6899999*****97 PP

  == domain 3  score: 8.2 bits;  conditional E-value: 0.0017
      zf-met   3 CelCnvtfnsesqlksHlq 21 
                 C  C+++++ +++ ++Hl+
  EEA19358.1 501 CGFCDKVLTTWQARIDHLA 519
                 *****************96 PP

>> zf-C2H2_2  C2H2 type zinc-finger (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   0.0     0.013        26      44      71 ..     379     406 ..     366     415 .. 0.81
   2 ?    2.8   0.8     0.074   1.5e+02      49      69 ..     430     450 ..     422     466 .. 0.84
   3 ?    1.4   0.0       0.2     4e+02       2      23 ..     501     522 ..     498     528 .. 0.79
   4 ?   -1.1   0.0       1.2   2.4e+03      15      29 ..     674     688 ..     665     690 .. 0.77

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.013
   zf-C2H2_2  44 rekieekleClyCekefkslealreHmk 71 
                 ++++ ++++C +C ++fk++ +   H k
  EEA19358.1 379 SNNVPKTFQCTFCTDSFKTKYDWSRHEK 406
                 46677899*********99999999854 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.074
   zf-C2H2_2  49 ekleClyCekefkslealreH 69 
                 ++ +C yC++++ + e+l++H
  EEA19358.1 430 DEPKCAYCNTSSPTEEHLHTH 450
                 5679****9999999999888 PP

  == domain 3  score: 1.4 bits;  conditional E-value: 0.2
   zf-C2H2_2   2 Clfcekkskeveellehmskkh 23 
                 C fc+k  +++++ ++h+  ++
  EEA19358.1 501 CGFCDKVLTTWQARIDHLAAHF 522
                 8888888888888888887665 PP

  == domain 4  score: -1.1 bits;  conditional E-value: 1.2
   zf-C2H2_2  15 llehmskkhgffipe 29 
                 +le+ ++ hgff+++
  EEA19358.1 674 WLEYFKERHGFFVDR 688
                 57889*******985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (691 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       684  (0.0381505); expected 358.6 (0.02)
Passed bias filter:                      388  (0.0216409); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.59u 0.31s 00:00:00.89 Elapsed: 00:00:00.45
# Mc/sec: 4591.74
//
Query:       EEA19359.1  [L=419]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.2e-19   70.8  16.8    1.5e-19   70.4  16.8    1.1  1  TPT         Triose-phosphate Transporter family
    2.8e-05   24.3  32.3     0.0049   17.1  12.4    2.6  2  EamA        EamA-like transporter family


Domain annotation for each model (and alignments):
>> TPT  Triose-phosphate Transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.4  16.8   1.7e-23   1.5e-19       2     290 .]      82     398 ..      81     398 .. 0.86

  Alignments for each domain:
  == domain 1  score: 70.4 bits;  conditional E-value: 1.7e-23
         TPT   2 klgllfllWYllnvvfnilnKkiln....vfpyPltvsavqllvgsvl.ilvlwal.glkk..................rpkisseflkailplalvkt 76 
                  ++ll +lW++++++  i+nK +++     fp+Pl++++++ +v   l +l+l+ +  l+                      ++  +l+ ++p +++ +
  EEA19359.1  82 SIALLAVLWHVFSLAISIYNKWMFSgdsiSFPFPLFMTSLHQVVQFALsALFLYLIpSLRPqrmslppsavlpgadpqrGMSLKRLYLIHLIPGGVATA 180
                 6899********************8554457****9999877766555155566665666589************985444444559************ PP

         TPT  77 lghvlavvslskvaVSfthtvKasePiFtvilsrlllgeklsllvylsLlpivgGvalasvtElsFnligfisAlisnltfslrnifsKkllkk.lkd. 173
                 l   l+++sl   +  f    K+s  +F  +++ l+  ek+s+ + l + ++ +G ++  + E++F l gf   + s +++ +r  +s  l+ k     
  EEA19359.1 181 LDMGLGNMSLRFSSLTFMTACKSSTLVFILLFAFLFGLEKPSVRLALIIAVMTVGEVMMVLGEVTFSLPGFALVTGSAFFSGFRWALSQLLILKhP-At 278
                 ********************************9999999999999999999999*9*********************************9998832.33 PP

         TPT 174 ldalnlfaiitilslllllPvallvegvlktpsllkst.k.vs.lkevllllllsgvlfhlynqvaymvLervspvthsvantvKrvvvIvlsvlvfkn 269
                  + + +++ ++ + ++ l+ +++ ve+ ++ ++ l +  +  + +++ + llll g l +      +++L+r s vt sv   +K vv+I ++ +vf++
  EEA19359.1 279 SNPVSMLFHLSPVVFVTLIGISISVEDPQEIIDALYALsEaCGsTSTAISLLLLPGCLAFCMVLSQFALLQRSSVVTLSVCGILKEVVIIGVAGVVFGD 377
                 7778899999*****************44444433333222444888999999********************************************** PP

         TPT 270 pvsllnaiGtavaivGvflYs 290
                 +++++n+ G++  ++ v+ Y+
  EEA19359.1 378 QLTSINICGVVAIMASVVAYN 398
                 *********999999999997 PP

>> EamA  EamA-like transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.8  12.0   1.1e-05       0.1      30     136 ..     115     240 ..      80     241 .. 0.74
   2 !   17.1  12.4   5.4e-07    0.0049       3     134 ..     250     396 ..     248     399 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.1e-05
        EamA  30 pltltf....vrfliagilllii.............allkegkl.aklslkdwlll.lllgllgtvlafllffyalkktsasnaslitslePvftlils 109
                 pl++t     v+f +++++l +i             a+l +  + + +slk + l+ l+ g ++t+l ++l +++l+ +s ++ + + s + vf+l+++
  EEA19359.1 115 PLFMTSlhqvVQFALSALFLYLIpslrpqrmslppsAVLPGADPqRGMSLKRLYLIhLIPGGVATALDMGLGNMSLRFSSLTFMTACKSSTLVFILLFA 213
                 344444555577888888888887777777777776444444445678888866666****************************************** PP

        EamA 110 vlllgekltlkqllgivlillGvllil 136
                 +l+  ek++++  l i+++ +G ++++
  EEA19359.1 214 FLFGLEKPSVRLALIIAVMTVGEVMMV 240
                 **********************88876 PP

  == domain 2  score: 17.1 bits;  conditional E-value: 5.4e-07
        EamA   3 gillallaalfwaiyfvlskillrkv....spltltfvrfliagillliiallkegkl....aklslkd........wllllllgllgtvlafllffya 85 
                 g  l+  +a+f+++ + ls+ l+ k+    +p++++f+ + + ++ l+ i+   e ++    a + l++        + llll g+l+++++ l +f +
  EEA19359.1 250 GFALVTGSAFFSGFRWALSQLLILKHpatsNPVSMLFHLSPVVFVTLIGISISVEDPQeiidALYALSEacgststaISLLLLPGCLAFCMV-LSQFAL 347
                 667788899999999999988854444555*******9999999999999554444444444222222233333331444455555555555.99**** PP

        EamA  86 lkktsasnaslitslePvftlilsvlllgekltlkqllgivlillGvll 134
                 l+++s+ + s++  l  v+++  + +++g +lt++ ++g+v i+++v+ 
  EEA19359.1 348 LQRSSVVTLSVCGILKEVVIIGVAGVVFGDQLTSINICGVVAIMASVVA 396
                 ************8888888888888888******************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (419 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       851  (0.047465); expected 358.6 (0.02)
Passed bias filter:                      387  (0.0215851); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.44
# Mc/sec: 2844.44
//
Query:       EEA19360.1  [L=198]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-09   38.3   0.0    1.8e-09   37.9   0.0    1.2  1  RNase_H   RNase H


Domain annotation for each model (and alignments):
>> RNase_H  RNase H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.9   0.0   9.9e-14   1.8e-09      18     107 ..      74     177 ..      59     198 .] 0.64

  Alignments for each domain:
  == domain 1  score: 37.9 bits;  conditional E-value: 9.9e-14
                 CEEEEEEECTT....E...EEEEEECCCCHHHHHHHHHHHHHHHTT.SC...........SEEEEEES-HHHHHHHHCCCHHHHHTTSSSETTSSBHTT CS
     RNase_H  18 eggagavlykeg..ar...nisapleeaqtnnraELsAvieaLkalksd...........ekvniytDSkYvvkgitqwvhrwkknawkttseqkpvkn 100
                 + +a++++y     ++    + + l ++ t  raEL+A i+aL +                 v i++DS Y+++g+t+wv +wk+++  ++  +  + n
  EEA19360.1  74 TVKAAIGVYLAPesKHnetRLLQDLDNPPTSHRAELEAGIQALITIMNIivvkgvegaklRMVIIKSDSAYLLQGVTHWVLQWKRHGVLDKRGEV-IEN 171
                 236666443222234434355577779****************975222466677777767788*******************999996665552.444 PP

                 HHHHHHH CS
     RNase_H 101 kdlaell 107
                   +   +
  EEA19360.1 172 -AIRFMV 177
                 .333332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (198 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       538  (0.0300073); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 1370.80
//
Query:       EEA19361.1  [L=193]
Description: hypothetical protein PMAA_001560 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (193 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       251  (0.0139997); expected 358.6 (0.02)
Passed bias filter:                      245  (0.013665); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.30s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 1282.04
//
Query:       EEA19362.1  [L=602]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.5e-22   77.7  44.3    7.5e-22   77.7  44.3    2.5  2  MFS_1            Major Facilitator Superfamily
    5.9e-16   58.0  23.9    8.1e-16   57.6  23.9    1.1  1  TRI12            Fungal trichothecene efflux pump (TRI12)
  ------ inclusion threshold ------
      0.078   12.0   6.1      0.017   14.2   2.2    1.8  2  ArAE_2_N         Putative ER transporter, 6TM, N-terminal


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.7  44.3   1.3e-25   7.5e-22       4     352 ..      74     481 ..      68     482 .. 0.79
   2 ?   -1.8   1.2      0.19   1.2e+03     103     103 ..     534     534 ..     488     578 .. 0.46

  Alignments for each domain:
  == domain 1  score: 77.7 bits;  conditional E-value: 1.3e-25
       MFS_1   4 aaflsalarsilgpalplalaedlg....ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlg 98 
                 a++   +  + +g+++  ++ +dlg     +++ +g+++ +  l ++v+s+++Grlsd + r+ +  +  l+ ++g+++ + a+s+ +l+ + +l G++
  EEA19362.1  74 AIVAQVFVVTGAGSVIA-FIIRDLGrdspDAGALAGWIIQGPLLMQSVLSPIVGRLSDVLDRKYIASVPPLIAFVGAVISAKATSIGMLIGGSILIGAT 171
                 45555555566666666.77777774332444449999999*******************888899999999999956666447777************ PP

       MFS_1  99 agalfpagaaliadwfpkeergraigllsagfslGailgpllgglla.sslg.Wravfyilaivsllafv.lfllllpeepperkrkspkeee...... 188
                   a +++++++ +++ p ++r++a+g++++g ++G i g l++g+++ ++ + Wr +f+i a++ +     l  ll++ + +++  ++   +e      
  EEA19362.1 172 L-ATIAIVQSIPSEILPLKHRALANGFAYMGGAIGGISGGLVAGAVTeANPSgWRDIFWIQAALHIATTAgL--LLFYHPTRRSDYPRMSFKEhfwacd 267
                 7.99999****************************************544447*************997755..6666666666666666666679*** PP

       MFS_1 189 ..................................................kgtgpaplvpawkallkdpvlw.illialllfffgfsglltllplylqe 236
                                                                    +    +lv     +  +p +  ++++ ++ +++++s++++ +p     
  EEA19362.1 268 pigslmfiasvtclllslnwaaglyawadvhvaaplgvglflfvlfclyeWKGRDDGLVA-HVFFQGSPNFAlSVFAFAVEGWIFYSAVTSVIPQV-TL 364
                 ****************99999999999999888887766666666666652222222222.44444555553356666666688888899999996.88 PP

       MFS_1 237 vlgls....glllaglllallalvgailallagrlsdrlgr.rrrlllallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdlap 330
                  lg+         +++   ++ + +a  +++++++s+r++  +++l+++++++l+a++ + ++ ++  + + + + +liG+gl+   ++l al++  ap
  EEA19362.1 365 YLGFEtsalR---ISIRGLAYNASAALCSMVITWYSTRTKDlKWPLVVTFGFFLVATITYTVITPA-MSKAQIGFNILIGIGLSGPLTLLVALVQFTAP 459
                 8999996442...44444444444444489******998777899999999999999999999999.88888889************************ PP

       MFS_1 331 peeagtasglfntagslggalg 352
                  ++  ta+gl+ +a+++gga+g
  EEA19362.1 460 HRHLSTATGLAFSARAVGGAFG 481
                 ********************98 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.19
       MFS_1 103 f 103
                 +
  EEA19362.1 534 V 534
                 1 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.6  23.9   1.4e-19   8.1e-16      50     565 ..      72     587 ..      32     597 .. 0.77

  Alignments for each domain:
  == domain 1  score: 57.6 bits;  conditional E-value: 1.4e-19
       TRI12  50 slnvvatyfvlqasasalpnilqdvgqsensslfstlwtt.g....qavsilvmgrltdrfgrrpfvilthilglvgaivgctatkfntllaamtllgv 143
                  + +va  fv+  + s +  i++d+g+   ++   + w + g    q+v   ++grl+d + r+ +  +  ++ +vga++ + at +  l+    l+g 
  EEA19362.1  72 CFAIVAQVFVVTGAGSVIAFIIRDLGRDSPDAGALAGWIIqGpllmQSVLSPIVGRLSDVLDRKYIASVPPLIAFVGAVISAKATSIGMLIGGSILIGA 170
                 45689*********************866555444555431444336777779*********************************************9 PP

       TRI12 144 aagpagasplfvgelmsnktkflgllivsipvvvtsglsp..ylgq.rlaiqgswrwifyiyiitsaiavllivvwyyppsfaqlhgkkvrkreelakl 239
                 +         +  e++  k + l      +   +  g+s     g    a    wr if+i   +   +   ++++y+p    +    +++ +e +   
  EEA19362.1 171 TLATIAIVQSIPSEILPLKHRALANGFAYMGGAI-GGISGglVAGAvTEANPSGWRDIFWIQAALHIATTAGLLLFYHPTR--RSDYPRMSFKEHFWAC 266
                 9888888888889999999888865544443322.2233200333313345577*******99887666666777777764..444567888899999* PP

       TRI12 240 dwigiilvivgvslfllgvswggkpnspwnsakviglissglgslvvfalyevygkpvrpivppalfkdtrgfvcillissimgamnlslvi.iypqqv 337
                 d ig ++ i+ v+ +ll + w       w   +v   +  gl  +v+f+lye  g+    +v   +f+ +  f   ++  ++ g +  s v  + pq  
  EEA19362.1 267 DPIGSLMFIASVTCLLLSLNWAAG-LYAWADVHVAAPLGVGLFLFVLFCLYEWKGRD-DGLVAHVFFQGSPNFALSVFAFAVEGWIFYSAVTsVIPQVT 363
                 *********************875.568************************99986.6899**********************998876551666655 PP

       TRI12 338 vnifgsslknweetaw.msatasfgtgagvvvlgslfhlvrhirwqilvga.lwltaflgamssvnrdnknaaialsvlsgfvvawaqditmllvqfit 434
                 +  +g      + +   ++  as       +v+       + ++w ++v   ++l a + + + +     +a i + +l g+ ++    + + lvqf +
  EEA19362.1 364 L-YLGFETSALRISIRgLAYNASAA--LCSMVITWYSTRTKDLKWPLVVTFgFFLVATI-TYTVITPAMSKAQIGFNILIGIGLSGPLTLLVALVQFTA 458
                 4.44544333333322023333332..23466667777899*****9998515666655.57788999999**********999999999999****** PP

       TRI12 435 tdedlgvafavvaaarpfagsiftaafislysnrypkelashlssalrgtdipqasfsslleaaksgrieavkalpgmtteiaavvsramadsytasya 533
                    +l  a  +  +ar + g+  +a + ++ +    +  as++s+a   +++p++ +s+ll a  +g   a+ ++pg+ + iaa    a  ++y+  y 
  EEA19362.1 459 PHRHLSTATGLAFSARAVGGAFGSAVLDAIINGVLRNTYASKVSTAAVDAGLPESGISALLAAMSAGT--ALTSVPGVNSTIAAAAEIASENAYAHVYH 555
                 **9998888887777776555444444445555555567899999999**************999995..999**********9999888887777777 PP

       TRI12 534 nvyyfamalgvipiiaslcmrdldryltdhvp 565
                   +   + + v+ i + lc++ +   +t+++ 
  EEA19362.1 556 LAWASIIPFVVLGIGSVLCLKGVKHLMTEKIE 587
                 77777777888899999*****9999999875 PP

>> ArAE_2_N  Putative ER transporter, 6TM, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   2.2   2.8e-06     0.017     147     217 ..     387     456 ..     377     469 .. 0.92
   2 ?   -2.7   0.1      0.39   2.3e+03     116     155 ..     535     574 ..     502     578 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 2.8e-06
    ArAE_2_N 147 llcvflffvgrlrakspkfalgaifgiIaadvfltyapmlPlfapgtlglallkPmgiglalkvvvsllif 217
                  lc++++   + r k+ k+ l+  fg++ +  ++ty++++P +++ ++g ++l   g++  l+++v+l+ f
  EEA19362.1 387 ALCSMVITWYSTRTKDLKWPLVVTFGFFLV-ATITYTVITPAMSKAQIGFNILIGIGLSGPLTLLVALVQF 456
                 688888889999****************99.9************************************977 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 0.39
    ArAE_2_N 116 ntsgaelaacaqeqvydgkmltarvsvvyavllcvflffv 155
                 n++ a++a +a+e +y+  +  a +s++ +v+l++  +++
  EEA19362.1 535 NSTIAAAAEIASENAYAHVYHLAWASIIPFVVLGIGSVLC 574
                 7888899999999999999999999999999999887776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (602 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       788  (0.0439511); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.63u 0.26s 00:00:00.89 Elapsed: 00:00:00.43
# Mc/sec: 4230.79
//
Query:       EEA19363.1  [L=481]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (481 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       434  (0.0242066); expected 358.6 (0.02)
Passed bias filter:                      388  (0.0216409); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 3361.52
//
Query:       EEA19364.1  [L=221]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-48  163.3   0.0    4.7e-13   49.5   0.0    2.7  4  Ank_2     Ankyrin repeats (3 copies)
    2.6e-28   98.0   0.0    9.7e-08   32.4   0.0    3.5  4  Ank_4     Ankyrin repeats (many copies)
    5.2e-19   67.8   0.3      2e-05   24.8   0.0    5.1  5  Ank       Ankyrin repeat
    4.2e-18   63.6   0.0     0.0002   21.5   0.0    5.9  6  Ank_3     Ankyrin repeat
    1.1e-15   57.5   0.0    2.1e-05   24.7   0.4    4.7  6  Ank_5     Ankyrin repeats (many copies)
  ------ inclusion threshold ------
       0.13   12.4   0.0       0.36   11.0   0.0    1.7  2  PilZ_2    Atypical PilZ domain, cyclic di-GMP receptor
       0.14   10.5   0.0       0.19   10.0   0.0    1.1  1  DUF3029   Protein of unknown function (DUF3029)


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.6   0.0   3.5e-11     9e-08       2      82 ..      14     104 ..      13     105 .. 0.79
   2 !   47.3   0.0   8.8e-16   2.3e-12       5      81 ..      50     137 ..      47     139 .. 0.82
   3 !   48.6   0.0   3.6e-16   9.3e-13      12      78 ..      90     167 ..      89     173 .. 0.84
   4 !   49.5   0.0   1.8e-16   4.7e-13       1      72 [.     113     193 ..     113     203 .. 0.89

  Alignments for each domain:
  == domain 1  score: 32.6 bits;  conditional E-value: 3.5e-11
       Ank_2   2 hlAakngnlelvklLl.egadpn.k..ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinlk 82 
                   Aak+ n+ +++ +l + +d + k   ++  L  A  +g++ ++  Ll+        d++g+tpL +A+ +  + +vklLle+ga++++k
  EEA19364.1  14 EEAAKHPNPGVFESMLkQLTDSEdKsiSEEELLLRASGRGDVAVATQLLQRgtdieaRDSSGWTPLLIAVMQHKTPMVKLLLEYGAEPDVK 104
                 5688854455777777555665542467899*********999999999866566655599*********99999************9886 PP

  == domain 2  score: 47.3 bits;  conditional E-value: 8.8e-16
       Ank_2   5 akngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh...ad....ndgrtpLhyAarsghleivklLlekgadinl 81 
                 +  g+  +  +Ll  g+d++  +  g+t+L +A+++ ++ +vklLle+    d       rtpLh Aa  g++ei +lLl + a++nl
  EEA19364.1  50 SGRGDVAVATQLLqRGTDIEarDsSGWTPLLIAVMQHKTPMVKLLLEYgaePDvkchLGIRTPLHQAADGGYEEITELLLTHRANPNL 137
                 44577788899999****998647*************99********88562243433367*******99**********99999997 PP

  == domain 3  score: 48.6 bits;  conditional E-value: 3.6e-16
       Ank_2  12 lvklLl.egadpn.k..ng.ktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgad 78 
                 +vklLl +ga+p+ k   g +t+Lh Aa +g++ei +lLl h       +++ r pL +Aa +ghl +vk+Ll++ga 
  EEA19364.1  90 MVKLLLeYGAEPDvKchLGiRTPLHQAADGGYEEITELLLTHranpnlYNDNRRRPLVFAAAEGHLSVVKMLLDHGAY 167
                 89*****99999883464559********************9966555447888***999999***********9974 PP

  == domain 4  score: 49.5 bits;  conditional E-value: 1.8e-16
       Ank_2   1 LhlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh.....adndgrtpLhyAarsghleivklL 72 
                 Lh+Aa  g+ e+ +lLl + a+pn  + n + +L +Aa +g+l +vk+Ll+h     +++d +tpL++A r+ +++iv+lL
  EEA19364.1 113 LHQAADGGYEEITELLLtHRANPNlyNdNRRRPLVFAAAEGHLSVVKMLLDHgaysqTKEDPETPLYWAKRHEYEDIVRLL 193
                 8******989*******9999999974699*********************998875448899****************87 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.2   0.0   1.9e-10   4.9e-07       3      55 .]      44      95 ..      42      95 .. 0.93
   2 !   28.8   0.0   5.2e-10   1.3e-06       8      55 .]      82     129 ..      82     129 .. 0.95
   3 !   32.4   0.0   3.8e-11   9.7e-08       2      55 .]     110     162 ..     109     162 .. 0.98
   4 !   21.4   0.0   1.1e-07   0.00027       2      54 ..     143     193 ..     142     194 .. 0.93

  Alignments for each domain:
  == domain 1  score: 30.2 bits;  conditional E-value: 1.9e-10
       Ank_4  3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55
                ++L +a   g++ ++  Ll++g di a+ ++sG+t+l iA++  +  ++klLl
  EEA19364.1 44 ELLLRASGRGDVAVATQLLQRGTDIEAR-DSSGWTPLLIAVMQHKTPMVKLLL 95
                56778888999999999***********.***********************8 PP

  == domain 2  score: 28.8 bits;  conditional E-value: 5.2e-10
       Ank_4   8 aaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 a+++ ++++v+lLle+ga+++  +    +t+lh Aa +g+ ei++lLl
  EEA19364.1  82 AVMQHKTPMVKLLLEYGAEPDVKCHLGIRTPLHQAADGGYEEITELLL 129
                 688999*****************889999*****************98 PP

  == domain 3  score: 32.4 bits;  conditional E-value: 3.8e-11
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +t+Lh+aa  g +e+ +lLl ++a++n   n++ + +l +Aa  g+++++k+Ll
  EEA19364.1 110 RTPLHQAADGGYEEITELLLTHRANPNLY-NDNRRRPLVFAAAEGHLSVVKMLL 162
                 79**************************9.***********************8 PP

  == domain 4  score: 21.4 bits;  conditional E-value: 1.1e-07
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54 
                 +++L  aa++g+l +v+ Ll++ga  + q+ ++ et+l+ A ++++ +i++lL
  EEA19364.1 143 RRPLVFAAAEGHLSVVKMLLDHGA--YSQTKEDPETPLYWAKRHEYEDIVRLL 193
                 789********************9..678789999****************98 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.12   3.1e+02       9      31 ..      49      72 ..      45      73 .. 0.76
   2 !   18.6   0.0   7.4e-07    0.0019       2      29 ..      75     103 ..      74     105 .. 0.92
   3 !   24.8   0.0   7.7e-09     2e-05       3      31 ..     110     139 ..     110     140 .. 0.92
   4 !   11.2   0.0   0.00016      0.41       5      25 ..     145     166 ..     144     171 .. 0.87
   5 ?    4.6   0.0     0.019        48       4      21 ..     176     193 ..     175     214 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.12
                HHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank  9 AatngkkriiklLL.hGAnlnald 31
                A+ +g++ ++  LL +G ++ a+d
  EEA19364.1 49 ASGRGDVAVATQLLqRGTDIEARD 72
                56566677888899669*****99 PP

  == domain 2  score: 18.6 bits;  conditional E-value: 7.4e-07
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlna 29 
                 G+TPL +A++  k+ ++klLL +GA+++ 
  EEA19364.1  75 GWTPLLIAVMQHKTPMVKLLLeYGAEPDV 103
                 9********999999******99**9986 PP

  == domain 3  score: 24.8 bits;  conditional E-value: 7.7e-09
                 BBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   3 nTPLHlAatngkkriiklLL.hGAnlnald 31 
                 +TPLH Aa +g ++i++lLL h+An+n+ +
  EEA19364.1 110 RTPLHQAADGGYEEITELLLtHRANPNLYN 139
                 5********999***************855 PP

  == domain 4  score: 11.2 bits;  conditional E-value: 0.00016
                 HHHHHHHHTTHHHHHHHH.TTT CS
         Ank   5 PLHlAatngkkriiklLL.hGA 25 
                 PL  Aa +g+++++k+LL hGA
  EEA19364.1 145 PLVFAAAEGHLSVVKMLLdHGA 166
                 66667779**********99*8 PP

  == domain 5  score: 4.6 bits;  conditional E-value: 0.019
                 BHHHHHHHHTTHHHHHHH CS
         Ank   4 TPLHlAatngkkriiklL 21 
                 TPL +A +   ++i++lL
  EEA19364.1 176 TPLYWAKRHEYEDIVRLL 193
                 9****88888899***88 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0      0.22   5.7e+02       3      22 ..      10      29 ..       8      37 .. 0.73
   2 ?    3.8   0.0     0.046   1.2e+02       5      30 ..      45      69 ..      42      70 .. 0.89
   3 !   21.5   0.0   7.9e-08    0.0002       2      30 ..      75     102 ..      74     103 .. 0.95
   4 !   13.7   0.0   2.8e-05     0.072       3      30 ..     110     136 ..     108     137 .. 0.93
   5 !   13.2   0.0     4e-05       0.1       3      27 ..     143     166 ..     141     168 .. 0.90
   6 ?    1.4   0.0      0.28   7.3e+02       3      21 ..     175     193 ..     173     197 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.22
       Ank_3  3 etpLhlAarsgnleivkfLl 22
                et L +Aa++ n+ + + +l
  EEA19364.1 10 ETSLEEAAKHPNPGVFESML 29
                899*********95544433 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.046
       Ank_3  5 pLhlAarsgnleivkfLlenkgadvn 30
                +L +A   g+++++  Ll+ +g d+ 
  EEA19364.1 45 LLLRASGRGDVAVATQLLQ-RGTDIE 69
                79999999***********.9***96 PP

  == domain 3  score: 21.5 bits;  conditional E-value: 7.9e-08
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G+tpL +A+++ ++++vk+Lle +ga+++
  EEA19364.1  75 GWTPLLIAVMQHKTPMVKLLLE-YGAEPD 102
                 9*********************.***987 PP

  == domain 4  score: 13.7 bits;  conditional E-value: 2.8e-05
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvn 30 
                 +tpLh+Aa  g  ei ++Ll  + a++n
  EEA19364.1 110 RTPLHQAADGGYEEITELLLT-HRANPN 136
                 8*******************9.899998 PP

  == domain 5  score: 13.2 bits;  conditional E-value: 4e-05
       Ank_3   3 etpLhlAarsgnleivkfLlenkga 27 
                 + pL +Aa  g+l++vk+Ll+ +ga
  EEA19364.1 143 RRPLVFAAAEGHLSVVKMLLD-HGA 166
                 679******************.786 PP

  == domain 6  score: 1.4 bits;  conditional E-value: 0.28
       Ank_3   3 etpLhlAarsgnleivkfL 21 
                 etpL++A r+   +iv++L
  EEA19364.1 175 ETPLYWAKRHEYEDIVRLL 193
                 8******999888877776 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0      0.31   7.9e+02      18      36 ..      11      29 ..       4      39 .. 0.81
   2 !   10.3   0.0   0.00027      0.69      23      56 .]      49      82 ..      43      82 .. 0.85
   3 !   18.2   0.0   8.8e-07    0.0023       1      52 [.      61     112 ..      61     112 .. 0.85
   4 !   19.1   0.1   4.6e-07    0.0012      18      47 ..     111     140 ..     105     142 .. 0.93
   5 !   24.7   0.4   8.2e-09   2.1e-05       1      40 [.     128     166 ..     128     181 .. 0.91
   6 ?    0.1   0.0      0.43   1.1e+03       1      33 [.     161     191 ..     161     193 .. 0.69

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.31
       Ank_5 18 tpLhvAakygaadvvrlLl 36
                t L  Aak+ ++ v++ +l
  EEA19364.1 11 TSLEEAAKHPNPGVFESML 29
                78888*********99999 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00027
       Ank_5 23 AakygaadvvrlLlargadlnltdsrGltaldlA 56
                A+ +g   v+  Ll rg d+ ++ds+G+t+l +A
  EEA19364.1 49 ASGRGDVAVATQLLQRGTDIEARDSSGWTPLLIA 82
                566777777777999****************988 PP

  == domain 3  score: 18.2 bits;  conditional E-value: 8.8e-07
       Ank_5   1 Llehg.padvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrG.lta 52 
                 Ll++g ++   ++ g+  tpL +A+ ++  ++v+lLl++ga +++++  G +t+
  EEA19364.1  61 LLQRGtDIEARDSSGW--TPLLIAVMQHKTPMVKLLLEYGAEPDVKCHLGiRTP 112
                 8999966666666666..**************************9987777776 PP

  == domain 4  score: 19.1 bits;  conditional E-value: 4.6e-07
       Ank_5  18 tpLhvAakygaadvvrlLlargadlnltds 47 
                 tpLh+Aa +g+ ++ +lLl ++a++nl+++
  EEA19364.1 111 TPLHQAADGGYEEITELLLTHRANPNLYND 140
                 9**************************996 PP

  == domain 5  score: 24.7 bits;  conditional E-value: 8.2e-09
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlarga 40 
                 Ll h+ a++n ++ ++  pL +Aa  g+++vv++Ll++ga
  EEA19364.1 128 LLTHR-ANPNLYNDNRRRPLVFAAAEGHLSVVKMLLDHGA 166
                 89999.******************************8775 PP

  == domain 6  score: 0.1 bits;  conditional E-value: 0.43
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvr 33 
                 Ll+hg  +   +d++  tpL +A ++ + d+vr
  EEA19364.1 161 LLDHGAYSQTKEDPE--TPLYWAKRHEYEDIVR 191
                 678886677788888..9999996655555555 PP

>> PilZ_2  Atypical PilZ domain, cyclic di-GMP receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0       1.3   3.2e+03      17      35 ..      72      90 ..      30     113 .. 0.63
   2 ?   11.0   0.0   0.00014      0.36      22      61 ..     144     183 ..     131     193 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 1.3
      PilZ_2 17 eekgeaelalqrldakldl 35
                +  g ++l++  ++ k  +
  EEA19364.1 72 DSSGWTPLLIAVMQHKTPM 90
                2223344444444444444 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 0.00014
      PilZ_2  22 aelalqrldakldllllllgrlarqqedalParPlrWsar 61 
                  +l     +  l ++ +ll + a  q + +P +Pl W++r
  EEA19364.1 144 RPLVFAAAEGHLSVVKMLLDHGAYSQTKEDPETPLYWAKR 183
                 55666677889**************************998 PP

>> DUF3029  Protein of unknown function (DUF3029)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   7.5e-05      0.19     367     414 ..      87     136 ..      81     141 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 7.5e-05
     DUF3029 367 vtpgvR..ipvGeEPelvkhlkasakfHkyfpsGisdiltldetvkknpe 414
                 +tp v+  +++G EP++  hl   +++H+  + G  +i +l  t + np+
  EEA19364.1  87 KTPMVKllLEYGAEPDVKCHLGIRTPLHQAADGGYEEITELLLTHRANPN 136
                 56666522589*************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (221 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       293  (0.0163422); expected 358.6 (0.02)
Passed bias filter:                      282  (0.0157287); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 1530.60
//
Query:       EEA19365.1  [L=568]
Description: phosphoglucomutase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.1e-14   52.8   0.0    7.7e-14   51.6   0.0    1.7  1  PGM_PMM_I    Phosphoglucomutase/phosphomannomutase, alpha/bet
    5.7e-07   29.7   0.0    9.7e-07   29.0   0.0    1.4  1  PGM_PMM_III  Phosphoglucomutase/phosphomannomutase, alpha/bet
    2.2e-06   28.2   0.0    4.5e-06   27.2   0.0    1.5  1  PGM_PMM_II   Phosphoglucomutase/phosphomannomutase, alpha/bet
    2.9e-05   24.1   0.0    9.4e-05   22.5   0.0    1.8  1  PGM_PMM_IV   Phosphoglucomutase/phosphomannomutase, C-termina


Domain annotation for each model (and alignments):
>> PGM_PMM_I  Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.6   0.0   1.7e-17   7.7e-14       2     130 ..      17     156 ..      16     163 .. 0.85

  Alignments for each domain:
  == domain 1  score: 51.6 bits;  conditional E-value: 1.7e-17
                 GGBBTTCEEEECCHCTBSCCHHHHHHHHHHHHCHHC.......STS-EEEEEE-S-TTHHH........HHHHHHHHHHCCT-CEEEEEEB-HHHHHHH CS
   PGM_PMM_I   2 qkfgtsGlRgkvgegeltpelveklgqaiaeylkae.......akkkkvvvGrDtRvssre........laealaaglaanGvevillgllptPavsfa 85 
                  kfgtsG Rg v  + lt+  ++  + a ++yl++        + +   + ++D R ss++        l +a+ + l   G+  ++lg +ptPa+ + 
  EEA19365.1  17 LKFGTSGRRGLVV-D-LTQLEIYTNVLAEIHYLQSLplseggiQSGDDFYYAYDLRPSSTKyvennrggLCQAVEQALKDGGMRPLNLGAIPTPALTYF 113
                 58********998.5.8888888888888899998888889999999************9844444444678999999999****************** PP

                 HHHCCECEEEEE--TTS-TTCCCEEEEETTTCE--CHHHHHHHHH CS
   PGM_PMM_I  86 irklkadagimitaSHnppeyngiKvylsnGgpispeveekIeai 130
                 + + + +++im+t+SH p ++ng+K+++s+G  ++++ e+ I + 
  EEA19365.1 114 ALQ-RGKGSIMVTGSHIPFDRNGYKLNTSKGELMKKD-EHPINDL 156
                 **9.78************************9766665.6766665 PP

>> PGM_PMM_III  Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.0   0.0   2.2e-10   9.7e-07       2     114 .]     305     425 ..     304     425 .. 0.83

  Alignments for each domain:
  == domain 1  score: 29.0 bits;  conditional E-value: 2.2e-10
                  HHHHHHHHHHHHHCHCSTTTCEEEEETTS-THHHHHHHHTT-EEEEESSSCHHHHHHHHHT...T..ECEEEETTCEEEETTT..........BSS-- CS
  PGM_PMM_III   2 gdqllallakylleeklkpgagvvktvmtslalervakklgiklvetkvGdkyvleemkee...g..avlGgEeSghiiflde..........attkD 84 
                  gd l++++a+ l++     +a  v +++ ++a++     ++i+  +tk+G+ yv++ m+     g   v+G E +g+++ +++            t+D
   EEA19365.1 305 GDLLGMIVAQFLRA-----DA-AVVPISANDAIDYG-SLAEITEPKTKIGSPYVIAGMQLAinkGrsHVCGWEANGGFLTGSDmkrngktlsaLPTRD 395
                  78889999998855.....45.7999*******988.55666666*************988655156999***********775666654444449** PP

                  HHHHHHHHHHHHHHHTS-HHHHHHHHHHHH CS
  PGM_PMM_III  85 Gilaallvleilaetgkslselleellkky 114
                  ++l+ l +l ++++++++l +l + l+k+y
   EEA19365.1 396 AMLPLLCALFAAKNEHMTLPDLFATLPKRY 425
                  ***********************9999998 PP

>> PGM_PMM_II  Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.2   0.0   9.9e-10   4.5e-06       2      99 ..     197     293 ..     196     297 .. 0.80

  Alignments for each domain:
  == domain 1  score: 27.2 bits;  conditional E-value: 9.9e-10
                 HHHHHGGGTS-HHHHHHHT-EEEEE-TT-TTHHHHHHHHHHTT-EEEES-----TT-TT...SS----TT-TTTTHHHHGGGGG-SEEEEE-TTS-BEE CS
  PGM_PMM_II   2 aYiealkekvdseaikksglkvvidplhGaggeilkellkelgvdvvelnaepdpdfpt...kapnpeekealkllielvkkegadlglafDgDaDRlg 97 
                 aYi+++++ +  e++++   ++++  + ++g+++l e+++++g++v++  a ++++f+    +a++  + +++++l + + +++ ++++++DgD DR  
  EEA19365.1 197 AYIQRFLDFFEGETLQGM--TILAYQHSAVGRDLLVEIFEKFGANVIP--AGRSETFVPidtEAIDQAQLDVVQKLYDQAGQSSINAMISTDGDSDRPL 291
                 799999999997777666..*************************988..888999998433444444455666666666667889***********87 PP

                 EE CS
  PGM_PMM_II  98 vv 99 
                 + 
  EEA19365.1 292 LL 293
                 75 PP

>> PGM_PMM_IV  Phosphoglucomutase/phosphomannomutase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5   0.0   2.1e-08   9.4e-05      26      68 ..     510     552 ..     483     560 .. 0.90

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 2.1e-08
                 CCCCCCCGCCEEEE.EEEETTCCEEEEEEEESSHHHHHHHHHH CS
  PGM_PMM_IV  26 keglkilledGrrlavRpSGTepllrvyvEaksdeelarlaee 68 
                  +g++  +++G ++  RpSG  + lr+y+ a+ +e+++++a +
  EEA19365.1 510 TDGVRMYFGNGDVAHFRPSGNADELRIYAIADQQERADDIAVQ 552
                 58999999*******************************9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (568 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       295  (0.0164538); expected 358.6 (0.02)
Passed bias filter:                      293  (0.0163422); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.24s 00:00:00.78 Elapsed: 00:00:00.42
# Mc/sec: 4041.80
//
Query:       EEA19366.1  [L=348]
Description: zinc-binding oxidoreductase ToxD, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.8e-09   36.3   0.0    8.8e-09   35.4   0.0    1.4  1  ADH_zinc_N  Zinc-binding dehydrogenase
    0.00028   20.7   0.0     0.0011   18.8   0.0    1.9  2  ADH_N       Alcohol dehydrogenase GroES-like domain


Domain annotation for each model (and alignments):
>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.4   0.0   9.9e-13   8.8e-09       2      69 ..     163     227 ..     162     240 .. 0.88

  Alignments for each domain:
  == domain 1  score: 35.4 bits;  conditional E-value: 9.9e-13
                 HHHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTESEEEETTTC.HHHHHHHHHTTTSSEEEEEESSCSH CS
  ADH_zinc_N   2 vGlaavqlAkalGaeviavdsseeklelakklGadevinykea.dlverikeltggegvdvvfecvGsg 69 
                  G +++q+Ak +G +vi+++s + +++++k+lGad  ++y ++ ++ ++i+e t ++++ ++ ++v  +
  EEA19366.1 163 TGALGIQFAKLSGYTVITACSPR-NFDYVKSLGADKWFDY-NEpNVGAQIREYT-QNKLEYAWDTVS-E 227
                 5999*************998766.7***************.666**********.89********98.3 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.0   1.3e-07    0.0011       3      61 ..      26      82 ..      24      90 .. 0.82
   2 ?   -0.8   0.0      0.16   1.4e+03      90     104 ..      91     106 ..      82     111 .. 0.72

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 1.3e-07
                EEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS.--TT-EEEE CS
       ADH_N  3 evlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkk.lkvGdrVvv 61
                 +l+k  a +++ +D + +       ++ +  lG +++G+veevg++v+k +++Gdr++ 
  EEA19366.1 26 YILVKPVAIALNPTDWKHAAF---GLAAEGGLLGCDFAGIVEEVGSKVTKkWQKGDRIAG 82
                578888888888888866554...36777889****************998******975 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.16
                 S.S-SSSBSEEEECGG CS
       ADH_N  90 s.ldGgfaeyvvvpek 104
                 + +dG+fae+++++ +
  EEA19366.1  91 QpQDGAFAEHILAKGD 106
                 2489******998855 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (348 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       240  (0.0133861); expected 358.6 (0.02)
Passed bias filter:                      229  (0.0127726); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.23s 00:00:00.65 Elapsed: 00:00:00.38
# Mc/sec: 2734.99
//
Query:       EEA19367.1  [L=1002]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.9e-07   29.3   0.0    2.2e-06   28.2   0.0    1.6  1  Methyltransf_11  Methyltransferase domain
  ------ inclusion threshold ------
      0.016   15.9   0.0      0.043   14.5   0.0    1.7  1  Methyltransf_25  Methyltransferase domain


Domain annotation for each model (and alignments):
>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.2   0.0   2.5e-10   2.2e-06      48      94 ..     771     827 ..     726     829 .. 0.72

  Alignments for each domain:
  == domain 1  score: 28.2 bits;  conditional E-value: 2.5e-10
                      TTEECCCTSS-TT-EEEEEEES-CCC-...C........CHHHHHHHHHHHEEEEEEE CS
  Methyltransf_11  48 vvadaeklpfednsfDlvvssevlhhv...e........dpekalkeiaRvLkpgGll 94 
                       v  + klpf++n+fD++ +++  h +   e        + + +lke++R+LkpgG+l
       EEA19367.1 771 SVPCLWKLPFRNNQFDVISARSL-HALlktErpdgeevdEYDLCLKECYRCLKPGGYL 827
                      4444458**********988874.444455155566666*****************98 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.0   4.8e-06     0.043      57      97 .]     777     825 ..     753     825 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 4.8e-06
                      GBSSSTTTEEEEEEESTGGGSSHHHHHH.........HHHHHHHHEEEEE CS
  Methyltransf_25  57 dlpfedgsfDlvvssgalhhlsdedlek.........alkeiarvLkpgG 97 
                      +lpf +++fD++ +  +lh l + ++++         +lke++r+LkpgG
       EEA19367.1 777 KLPFRNNQFDVISA-RSLHALLKTERPDgeevdeydlCLKECYRCLKPGG 825
                      79************.47775322222222334455559***********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1002 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       399  (0.0222544); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.69u 0.28s 00:00:00.97 Elapsed: 00:00:00.47
# Mc/sec: 6389.84
//
Query:       EEA19368.1  [L=103]
Description: small nuclear ribonucleoprotein (LSM2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.6e-18   65.4   0.8    3.4e-18   65.1   0.8    1.2  1  LSM       LSM domain
     0.0051   16.3   0.1     0.0058   16.1   0.1    1.1  1  LRR_9     Leucine-rich repeat
  ------ inclusion threshold ------
      0.041   13.5   0.0      0.064   12.9   0.0    1.3  1  Hfq       Hfq protein
       0.15   12.3   0.0       0.18   12.0   0.0    1.2  1  SM-ATX    Ataxin 2 SM domain


Domain annotation for each model (and alignments):
>> LSM  LSM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.1   0.8   7.5e-22   3.4e-18       2      66 ..       6      71 ..       5      72 .. 0.96

  Alignments for each domain:
  == domain 1  score: 65.1 bits;  conditional E-value: 7.5e-22
                HHHHTTTSEEEEEETTSEEEEEEEEEEETTSEEEEEEEEEEETTET.EEEEEEEEEEEGGGEEEEE CS
         LSM  2 flkklinkkvtvelkngrelrGtLkgfDqfmNlvLedveetlkdkk.ekrklglvliRGnnivlis 66
                f+k l+n++vtvelkn+ ++rGtLk++Dq++N+ L+dv + + dk  +  ++++++iRG+ +++++
  EEA19368.1  6 FFKTLTNHIVTVELKNDIRIRGTLKSVDQYLNIKLDDVDVLDLDKYpHLSSVKNMFIRGSVVRYVV 71
                899***************************************99999*****************98 PP

>> LRR_9  Leucine-rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.1   1.3e-06    0.0058      40      73 ..      31      64 ..      11      76 .. 0.89

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 1.3e-06
       LRR_9 40 tldqfdtidlsdndirkldgfPllkrlktlllnn 73
                ++dq+  i+l+d d+ +ld +P+l  +k +++  
  EEA19368.1 31 SVDQYLNIKLDDVDVLDLDKYPHLSSVKNMFIRG 64
                78**************************999865 PP

>> Hfq  Hfq protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   1.4e-05     0.064      15      37 ..      14      36 ..       8      44 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.4e-05
                EEEEEETTS-EEEEEEEEE-SSE CS
         Hfq 15 pvtifLvnGiklkGviksfDnft 37
                 vt+ L n i+++G++ks D++ 
  EEA19368.1 14 IVTVELKNDIRIRGTLKSVDQYL 36
                69*******************96 PP

>> SM-ATX  Ataxin 2 SM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0     4e-05      0.18      14      51 ..      13      48 ..       3      77 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 4e-05
                SEEEEEETTS-EEEEEEEEE-T..T--EEEEEEEETTS CS
      SM-ATX 14 kevevtvknGevyeGifstvslekdfsvvLkmarkvkk 51
                + v+v++kn+ +++G +++v+    +++ L+ + +++ 
  EEA19368.1 13 HIVTVELKNDIRIRGTLKSVDQ--YLNIKLDDVDVLDL 48
                679*******************..99999999988887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (103 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       446  (0.0248759); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 754.98
//
Query:       EEA19369.1  [L=327]
Description: endo alpha-1,4 polygalactosaminidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.4e-89  298.6   2.5      3e-89  298.3   2.5    1.1  1  Glyco_hydro_114  Glycoside-hydrolase family GH114
  ------ inclusion threshold ------
      0.024   14.7   1.0        0.4   10.8   0.5    2.4  2  ETRAMP           Malarial early transcribed membrane protein 
       0.12   12.6   0.2       0.27   11.4   0.2    1.6  1  RuBisCO_large_N  Ribulose bisphosphate carboxylase large chai


Domain annotation for each model (and alignments):
>> Glyco_hydro_114  Glycoside-hydrolase family GH114
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  298.3   2.5   5.1e-93     3e-89       1     232 []      89     322 ..      89     322 .. 0.97

  Alignments for each domain:
  == domain 1  score: 298.3 bits;  conditional E-value: 5.1e-93
  Glyco_hydro_114   1 twqyqlqgpletspdavdvydiDlfdtsaatiaalkakgkkviCYfsaGevedwrpdaddfnpasvlgkkldgWpgerwldirtaakrsskvrs 94 
                      twq++l  +l+ +  +v+vydiDlfdt+a++i++l+a+g+kviCYfsaG++e+wrpdad+f ++s+lg++l+gWpge+wl+i+     ss+vr+
       EEA19369.1  89 TWQIELLYKLNDTSIDVQVYDIDLFDTQADQISSLQAAGRKVICYFSAGSWENWRPDADQF-NSSDLGGDLNGWPGEKWLNIS-----SSSVRN 176
                      7******999988666*********************************************.999******************.....999*** PP

  Glyco_hydro_114  95 imkaridlaaakGfdgvepDnvDsyesnd.tgflltaadqlayvkflaaeaharglaiglknageliselvdafdfavnEecaeyseCdtyepf 187
                      im +r+  a++kG++gv+pDnvD+y sn+ ++++lt++d+++yv+fla+eahar+++iglknag++i++++d+++++vnE+ca+y eC++++pf
       EEA19369.1 177 IMVNRLHIAQQKGCNGVDPDNVDGY-SNSeNALGLTQQDSIDYVNFLASEAHARNMSIGLKNAGDIIDSVIDNMQWSVNEQCAQYGECKKFTPF 269
                      *************************.788899************************************************************** PP

  Glyco_hydro_114 188 iaagkpVfhiEYp..........vsaaedaaacaaasraagfstvvkdldLddkw 232
                      ++a+kpVfhiEYp          v++a+++aac   +++ +fstv+k++dL d+w
       EEA19369.1 270 TDANKPVFHIEYPkgvdtnnanhVTSAQKQAACV-FEGSGKFSTVIKNMDL-DNW 322
                      **********************9999999*****.****************.565 PP

>> ETRAMP  Malarial early transcribed membrane protein (ETRAMP)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.5   6.7e-05       0.4      51      80 ..      17      46 ..       8      49 .. 0.78
   2 ?    1.4   0.0     0.058   3.5e+02      16      47 ..     219     250 ..     217     256 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 6.7e-05
      ETRAMP 51 kkkKliiistiatalallvasalGlgiykk 80
                kkk  iii+++++++al +++  Glg+  +
  EEA19369.1 17 KKKTVIIIAMVSSIVALGIGLGAGLGVGLH 46
                677778888999999999999888887655 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.058
      ETRAMP  16 vnlltpeslcdevnkkkekakkaikkiddkie 47 
                 vn+l++e+++ +     ++a++ i+++ d+++
  EEA19369.1 219 VNFLASEAHARNMSIGLKNAGDIIDSVIDNMQ 250
                 89********9999888999999999999986 PP

>> RuBisCO_large_N  Ribulose bisphosphate carboxylase large chain, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.2   4.6e-05      0.27      28      92 ..      55     123 ..      46     135 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 4.6e-05
  RuBisCO_large_N  28 veeaaaavAaeSStgtwtevsttkdellkklkakvyeieevee.ekelvki.AYplelFeeg..sipql 92 
                       +++a+  Aa + t+t t+ st + ++++   +++++ie + + +++ + +  Y+++lF+++  +i++l
       EEA19369.1  55 ATSTATVSAAPAATATATSTSTSNGTFWQPTAGTTWQIELLYKlNDTSIDVqVYDIDLFDTQadQISSL 123
                      456778889999**************************998778555555535*******975555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (327 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       930  (0.0518713); expected 358.6 (0.02)
Passed bias filter:                      578  (0.0322383); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 2190.27
//
Query:       EEA19370.1  [L=826]
Description: DNA repair protein Pso2/Snm1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.8e-34  118.3   0.0    3.8e-34  117.2   0.0    1.6  1  DRMBL          DNA repair metallo-beta-lactamase
    2.8e-06   27.0   0.0    5.4e-06   26.1   0.0    1.4  1  Lactamase_B_2  Beta-lactamase superfamily domain
  ------ inclusion threshold ------
      0.023   14.7   0.0      0.047   13.7   0.0    1.5  1  Lactamase_B    Metallo-beta-lactamase superfamily


Domain annotation for each model (and alignments):
>> DRMBL  DNA repair metallo-beta-lactamase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.2   0.0   6.4e-38   3.8e-34       1     110 []     666     795 ..     666     795 .. 0.95

  Alignments for each domain:
  == domain 1  score: 117.2 bits;  conditional E-value: 6.4e-38
       DRMBL   1 pelesllttdpseaqihlvslkklekeklekylkalkekfdsvlafrPtGWtkkekkkkdlekikess......................ksrekisiy 77 
                 pel+sllt++p+eaqih+  + +++ e+l++yl+++k +f++v++frPtGWt++++  + l+  ++ +                      +s+++ s++
  EEA19370.1 666 PELSSLLTDNPLEAQIHMQIVFEIRAETLSDYLQSFKGHFSRVVGFRPTGWTYRPPGGRLLD--NPPVanvlhssnwktsfsvsdlvpqrGSNKEASCF 762
                 5789****************************************************888887..5555689**************************** PP

       DRMBL  78 rvpYSeHSSfrELkefvkslkpkkiiptVnvgn 110
                 +vpYSeHSSfrEL++f+++l++ +iiptVnvgn
  EEA19370.1 763 GVPYSEHSSFRELTMFCCALRIGRIIPTVNVGN 795
                 ******************************986 PP

>> Lactamase_B_2  Beta-lactamase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.1   0.0     9e-10   5.4e-06      29     160 ..     416     534 ..     408     578 .. 0.78

  Alignments for each domain:
  == domain 1  score: 26.1 bits;  conditional E-value: 9e-10
                    .SEEEEE-SS--HHHHGGGGCCCCC--EEEEEEEEHHHHHHCCTTCGHHHCHTTTTEEEEEE-TTSEEEE.CSTTEEEEEEEE-EE--CTCCE-TT CS
  Lactamase_B_2  29 ppidaVllthaHyDHlaglltlrelrpkklplyapkgvlavleanfvylaleeepavnvheldwgesfel.gdggleitatparhksgrrldrnag 123
                    +  +a +l+h H DH+ gl      +    p+y+++ ++  ++++++    +++    v++l+ ++++e+ +  g+ +t+ pa+h  g       +
     EEA19370.1 416 EGCQAYFLSHFHSDHYGGLTGSWS-H---GPIYCSRVTGNLVRQQLK---VDPK---YVVDLEFEKKTEVpNTKGVYVTMLPANHCPGS------S 495
                    5678889*********99777666.3...48**************64...3344...6889********99556899***********9......7 PP

                    TSEEEEEE..CTTEEEEEESS-S---HHHHHHHCT-SEE CS
  Lactamase_B_2 124 dtlGlrie..gggkrvyyigDtgyipeeigerlggadll 160
                    ++l   i   g  +rv+++gD   +p++++  l ++d+l
     EEA19370.1 496 LFLFEKIMdnGRIHRVLHCGDFRACPAHVQHPLLKPDIL 534
                    777777775555579***********9998666556554 PP

>> Lactamase_B  Metallo-beta-lactamase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   7.8e-06     0.047      49      67 ..     422     440 ..     408     496 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 7.8e-06
                  E-SBSSHHHHTTGGGCTTH CS
  Lactamase_B  49 ilTHlHlDHiGglgglvea 67 
                  +l+H+H+DH+Ggl g  ++
   EEA19370.1 422 FLSHFHSDHYGGLTGSWSH 440
                  89**********9875555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (826 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       844  (0.0470746); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.71u 0.27s 00:00:00.98 Elapsed: 00:00:00.44
# Mc/sec: 5584.77
//
Query:       EEA19371.1  [L=517]
Description: cytochrome P450 benzoate 4-monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-96  324.2   0.0    1.5e-96  324.0   0.0    1.0  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  324.0   0.0  8.2e-101   1.5e-96       3     459 ..      41     508 ..      39     512 .. 0.93

  Alignments for each domain:
  == domain 1  score: 324.0 bits;  conditional E-value: 8.2e-101
                 SES.EHHCCHCHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHHH CS
        p450   3 gpt.plplvgnllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkklRr 100
                 +++ +++ ++ + q + ++ ++ ++++++kkyg+++r+ +++   v + + ea+++v+++++ + ++++++a+++++r+ f++++ + +++++++  ++
  EEA19371.1  41 PFPaAYTNLWLFWQAR-RGRRFLAVNDAHKKYGKFVRIAPNH---VSIADDEAIQAVYGHGNGFLKSDYYDAFVSIRRGLFNTRDRAEHTRKRKTVAHT 135
                 5552455555555555.6889999***************987...6677888*********************************************** PP

                 HHHHHHTSH..STT.THHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSH...........HHHHHHHHHHHHH..H CS
        p450 101 fltptltsf..gkl.sleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledek...........lselvkaveelss..l 183
                 f+ +++ +f  +++ ++e +v + ++  + + ++++g + ++d  +++++ a+d+ig+++Fga+f++le+ k           ++++  a+e l++  +
  EEA19371.1 136 FSAKSIGQFeqYIHaNVELFVVQLTKLSQLQRNPRTGYA-SIDALNWFNYLAFDIIGDLAFGAPFGMLEKGKdvaevrktpdsPPTYAPAIEVLNRrgE 233
                 *********999998999999999998888888888888.6******************************************99**********9999 PP

                 HHCHHHHCCCCCHHHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHH CS
        p450 184 lskssvqllllfpllkylptkllrklkeavkklkdlldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstl 282
                 +s +   + +l+p + +lp++++ k  eav+ l++++ + + er +   +++++r+d+l+ l++ + ++ g  kl +eel+a++l+ l+aG+dTts+t 
  EEA19371.1 234 VSGTLGIMPFLKPYAAFLPDSFFSKGLEAVENLAGIAVARVSERLKPEVMENNTRVDLLARLMEGR-DETGA-KLGREELTAEALTQLIAGSDTTSNTA 330
                 99***************************************************************8.88886.************************** PP

                 HHHHHHHHHSHHHHHHHHHHHHHHC.CTTTT-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS...CEEETTEEE-TT-EEEEEHHHHHT-TTTS CS
        p450 283 swaLyeLaknPevqeklreEidevl.gdkreptyddlqklpyldavikEtLRlhpvvplllpRevtk...dvvirgylipkGtevivnlyalhrdpevf 377
                 +  Ly+ +++P v++kl+e +de+l  +++ pt+++l+++py + vi+Et+R+h+++ l+lpR+++    +v i g+++ +G++v+v+ y++h++ +++
  EEA19371.1 331 CALLYWVLRTPGVMKKLQECVDEALpDGVEVPTFAMLKDIPYIQYVIQETMRIHSTSSLGLPRQIPPgsaPVNICGRTFHAGDVVSVPSYTIHHSTKIW 429
                 *************************88889***********************************87777***************************** PP

                 .SSTTS--GGGGB-TTSCTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGEEESSCSSEEESSSS CS
        p450 378 .pnPeeFdpeRFldekgnskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdpppileksglllppkpi 459
                  p++eeF p+R+ +e+  + r++ af+PF++GpR+C+G+++A+mel  +++t+++nFe+ l +e+++++++   g+l++p ++
  EEA19371.1 430 gPDAEEFVPDRWAPERL-TARQKSAFIPFSTGPRACVGRNVAEMELTCIVGTVFRNFEFVLEQEEKMETRE---GFLRKPLGL 508
                 ****************9.67****************************************95544444443...588888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (517 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       482  (0.0268838); expected 358.6 (0.02)
Passed bias filter:                      451  (0.0251548); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.29s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 3424.66
//
Query:       EEA19372.1  [L=177]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-15   57.0  14.1    1.4e-05   25.4   1.6    3.1  3  SMP       Seed maturation protein
     0.0025   17.7   0.4     0.0025   17.7   0.4    2.4  3  Ifi-6-16  Interferon-induced 6-16 family


Domain annotation for each model (and alignments):
>> SMP  Seed maturation protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.5     3e-07    0.0027      13      51 ..      17      54 ..      11      55 .. 0.89
   2 !   21.9   0.5     2e-08   0.00018      19      57 ..      77     114 ..      67     116 .. 0.84
   3 !   25.4   1.6   1.6e-09   1.4e-05      11      55 ..     121     164 ..     114     168 .. 0.85

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 3e-07
         SMP 13 lagdkpVtpeDAaavqaAEaraageartapgGvAaaaqa 51
                +a+++  t+eD   +++AE   +g  ++++gG+Aa+a++
  EEA19372.1 17 AAAGQRFTSEDVSCIAQAESELTG-GGPVKGGPAATAHS 54
                6889999*****************.6789*******975 PP

  == domain 2  score: 21.9 bits;  conditional E-value: 2e-08
         SMP  19 VtpeDAaavqaAEaraageartapg..GvAaaaqaAAdaNe 57 
                 +t+eDA   q+AE ra    + +pg   v a++++ Ad+Ne
  EEA19372.1  77 ITQEDARQLQSAEGRAFN--A-PPGvaSVSAQVRSIADRNE 114
                 8****************9..4.55543588**********8 PP

  == domain 3  score: 25.4 bits;  conditional E-value: 1.6e-09
         SMP  11 aklagdkpVtpeDAaavqaAEaraageartapgGvAaaaqaAAda 55 
                  +++g   Vt+e A   q+ Ea ++g ++ ++gG Aa++q+AAd+
  EEA19372.1 121 VQDPGPVYVTKEEASEAQSVEAMHTGGMV-PKGGYAAQLQSAADK 164
                 556777789*****************777.8899*********96 PP

>> Ifi-6-16  Interferon-induced 6-16 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.2     0.036   3.2e+02      20      37 ..      39      56 ..      27      60 .. 0.73
   2 ?   -3.4   0.0         1   9.3e+03      27      36 ..     100     109 ..      95     111 .. 0.60
   3 !   17.7   0.4   2.8e-07    0.0025      30      58 ..     134     162 ..     129     172 .. 0.92

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.036
    Ifi-6-16 20 taaGiaagSlAAkmmSaa 37
                t +G + g  AA  +S++
  EEA19372.1 39 TGGGPVKGGPAATAHSLS 56
                667777777777777765 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 1
    Ifi-6-16  27 gSlAAkmmSa 36 
                  S+ A++ S+
  EEA19372.1 100 ASVSAQVRSI 109
                 3556666655 PP

  == domain 3  score: 17.7 bits;  conditional E-value: 2.8e-07
    Ifi-6-16  30 AAkmmSaaAianGGgVaaGslvAvlQSaG 58 
                 A++ +S+ A+ +GG V++G+  A lQSa+
  EEA19372.1 134 ASEAQSVEAMHTGGMVPKGGYAAQLQSAA 162
                 8899***********************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (177 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       308  (0.0171789); expected 358.6 (0.02)
Passed bias filter:                      229  (0.0127726); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.45
# Mc/sec: 1174.65
//
Query:       EEA19373.1  [L=231]
Description: hypothetical protein PMAA_001680 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (231 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       390  (0.0217525); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.30s 00:00:00.80 Elapsed: 00:00:00.49
# Mc/sec: 1414.95
//
Query:       EEA19374.1  [L=300]
Description: hypothetical protein PMAA_001690 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.7e-14   51.9   0.0    7.8e-14   51.4   0.0    1.2  1  DUF3435   Protein of unknown function (DUF3435)


Domain annotation for each model (and alignments):
>> DUF3435  Protein of unknown function (DUF3435)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.4   0.0   4.3e-18   7.8e-14       2      84 ..     216     296 ..     215     300 .] 0.91

  Alignments for each domain:
  == domain 1  score: 51.4 bits;  conditional E-value: 4.3e-18
     DUF3435   2 eDllellrvlltttekrfqlgrqrvqlllllllaaftsnRpgalleLryrDleltlikdPeggrpvllvevtpeftKgklGkk 84 
                 e+ +e+ +++++ +   f+ +rqrvq++ +lllaa+t++Rpgall++ yrDl+l + k+ + g + l + vt+  tK   G+k
  EEA19374.1 216 EEFMEVIQYHWAADINIFPNERQRVQVAAILLLAAYTGSRPGALLNITYRDLRLNMEKHRKTGKHELKLAVTLTKTKS--GQK 296
                 78899**************************************************************99999766664..444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (300 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       562  (0.0313459); expected 358.6 (0.02)
Passed bias filter:                      357  (0.0199119); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 2025.88
//
Query:       EEA19375.1  [L=118]
Description: hypothetical protein PMAA_001700 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-22   79.7   0.0    2.2e-22   79.6   0.0    1.0  1  DUF3435   Protein of unknown function (DUF3435)


Domain annotation for each model (and alignments):
>> DUF3435  Protein of unknown function (DUF3435)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.6   0.0   1.2e-26   2.2e-22     101     210 ..       6     114 ..       1     118 [] 0.95

  Alignments for each domain:
  == domain 1  score: 79.6 bits;  conditional E-value: 1.2e-26
     DUF3435 101 vlsPhvfllgllfrdeAFkspsltsaedlyrlkvpkgrqqlpLklkpemldipvFcraereaegvrilkdealtastlnsrlkrlgeiagfeepitpYk 199
                 +++ ++++++++f deA+++p+  s + l++lk +k+   + +++k+emldipvF+ra ++++gv+++kd al++++ + +l  lg   gf  ++t Y+
  EEA19375.1   6 LFCIITHMISIAFDDEAYDAPKHFSLRHLFALKAKKKPS-QIVPWKQEMLDIPVFRRAIKTPQGVETSKDVALSYQQYHGWLVLLGIALGFIYTLTTYC 103
                 69********************9**********887766.889******************************************************** PP

     DUF3435 200 lRrgaakalne 210
                 lRr+ ++a+n+
  EEA19375.1 104 LRRALGNAINS 114
                 **********8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (118 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       432  (0.024095); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.43
# Mc/sec: 830.89
//
Query:       EEA19376.1  [L=307]
Description: hypothetical protein PMAA_001710 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-07   30.4   0.0    2.7e-07   29.9   0.0    1.1  1  DUF3435   Protein of unknown function (DUF3435)


Domain annotation for each model (and alignments):
>> DUF3435  Protein of unknown function (DUF3435)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.9   0.0   1.5e-11   2.7e-07     296     374 ..      58     136 ..      53     166 .. 0.86

  Alignments for each domain:
  == domain 1  score: 29.9 bits;  conditional E-value: 1.5e-11
     DUF3435 296 kreelkkeleakygqvakakgtelyeelekakrelrnerqrlrrelkkkireeFkeeqpvidierqlsGkaldeevked 374
                   ++l +++e+ +g ++ akg + y++++ +k+ l+ + ++  r+l k+i+ee++ + pv  i++ql G++ d++ ++d
  EEA19376.1  58 DSSRLCAQIEEAFGVIEMAKGEPIYNDYQAVKASLAATIRKKERALLKRIQEEYDLNAPVLAIQQQLNGEQSDDDNDDD 136
                 56777888999************************************************************88883333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (307 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       562  (0.0313459); expected 358.6 (0.02)
Passed bias filter:                      490  (0.02733); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2135.18
//
Query:       EEA19377.1  [L=453]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-16   61.0   0.0    3.4e-16   59.9   0.0    1.5  1  APH              Phosphotransferase enzyme family
  ------ inclusion threshold ------
       0.04   13.1   0.0      0.063   12.5   0.0    1.2  1  Fructosamin_kin  Fructosamine kinase


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.9   0.0   3.8e-20   3.4e-16       3     229 ..      47     337 ..      45     345 .. 0.77

  Alignments for each domain:
  == domain 1  score: 59.9 bits;  conditional E-value: 3.8e-20
                 EEE--.SSCEEEEEEETT-.-EEEEEE-TT...S-HHHHHHHHHHHHHHHHTT-.B--B-CTTBS-EEETTEEEEEEE----EE-SS............ CS
         APH   3 relsggasnrtylvttpag.ryvlrrnppa...raaeeirrevallrlLakagv.pvPevlagdtddeeigllfalieyvpgrsllr............ 84 
                  ++s+ga n  y+vt  +g r+++r+ + +      e++++eva++++La++ + pvP+v+    ++  +  ++ +++ ++g  l+             
  EEA19377.1  47 SRFSNGAFNLCYRVTYQDGsRVLVRFTALGrvlLRNEKVEDEVAVMKYLAQNTPiPVPKVIG---SGKCAVGPYMVMTMIEGSLLSGylkdplqemvtl 142
                 67999*************55999***99998888899*************66666*******...4444444799999999999999777777777777 PP

                 ..HHHHHHHHHHHHHHHHHHC.................................CHHCH.-STTTB-SHHCHTCC.HHHHHHCHHHCCCGCCTCCHHHH CS
         APH  85 ..klsaaqlpellealgefla.................................alhqvdpaalpladflaqdle.llrqlesatarllaselldllee 147
                   +   + l+++++ ++e                                    +l q+   + p+  f++q+ +  + ++e+ ++++l ++ ++ + +
  EEA19377.1 143 npTIPISALKRAYYGMAEIMLelskssfpfigalkedgfggwdvhkrpltfnmnRLAQF--SNIPPGIFAKQRFTnTADYFEELAKQHLYHLEFQ-RND 238
                 77666667777777777777777777777777777777777766666666666655555..4455555555444425566666666777777777.555 PP

                 HHHHHHHHHHHH--S...............SS-EEEE-SS-SGGGEEEC..TTEEEEE---TT-EEEECCHHH...HCCHHHCSCHCCCHCHHHHHHHH CS
         APH 148 leeqvlaalaallpg...............elptvllHgDlhpgNllvdpddgrvtGviDfedaglgpplyDl...avllrswtseldpeflaallray 228
                 + +  ++++++  ++               ++p +l   Dl+pgN+l+d+ +  v+G iD+e++ ++p+ +     ++ll   + e++++ l+++l++y
  EEA19377.1 239 AVKDEADCRKKYIARclfhkisrgipkehrDGPFRLFCDDLRPGNILIDASKLTVSGAIDWEFTYAAPAEFTYtapWWLL-LARPEEWEADLNQFLARY 336
                 655555555555555555555578888**99******************999*****************99999998888.448999******999999 PP

                 C CS
         APH 229 e 229
                  
  EEA19377.1 337 M 337
                 6 PP

>> Fructosamin_kin  Fructosamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0     7e-06     0.063      18      95 ..      42     124 ..      28     133 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 7e-06
  Fructosamin_kin  18 eiteaekveggeineaylls.eeeqrfFvklne....kealemFeaEaesLealaetqtirvPkvlavGelkdasfLvleyLe 95 
                      + t+a++ + g  n +y+++ ++ +r+ v+  +        e  e E++ ++ la+ ++i vPkv+  G++    ++v+  +e
       EEA19377.1  42 TPTTASRFSNGAFNLCYRVTyQDGSRVLVRFTAlgrvLLRNEKVEDEVAVMKYLAQNTPIPVPKVIGSGKCAVGPYMVMTMIE 124
                      567888999999999*999966778999999987644345688999********************************99887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (453 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       401  (0.022366); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.40
# Mc/sec: 3438.16
//
Query:       EEA19378.1  [L=103]
Description: hypothetical protein PMAA_001730 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
      0.077   12.9   0.8       0.12   12.3   0.8    1.2  1  Phycobilisome  Phycobilisome protein


Domain annotation for each model (and alignments):
>> Phycobilisome  Phycobilisome protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.8   6.8e-06      0.12       9      57 ..      51      99 ..      50     102 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 6.8e-06
                   TTS---HHHHHHHHHHHHTHHHHHHHHHHHHHTHHHHHHHHHHHHHHHS CS
  Phycobilisome  9 egrylssseleslkefvasgnkrldaakalasnaseivkeAvaklleen 57
                   +g+++s ++ e+lk+ ++ + +  da + l++ ++ei ++A+++ l+++
     EEA19378.1 51 KGAVPSAEQGEELKKALKLAMETQDALANLSAAEKEIMSQAANASLRKR 99
                   78999**************************************998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (103 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       896  (0.0499749); expected 358.6 (0.02)
Passed bias filter:                      506  (0.0282224); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.28s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 715.26
//
Query:       EEA19379.1  [L=289]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0016   18.4   1.2     0.0016   18.4   1.2    2.4  2  Atthog    Attenuator of Hedgehog
  ------ inclusion threshold ------
          2    8.4  10.0      0.067   13.1   1.3    2.3  2  DUF2678   Protein of unknown function (DUF2678)


Domain annotation for each model (and alignments):
>> Atthog  Attenuator of Hedgehog
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   1.2     0.015   1.3e+02      40      84 ..      91     135 ..      82     143 .. 0.86
   2 !   18.4   1.2   1.7e-07    0.0016      10      89 ..     181     260 ..     172     276 .. 0.90

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.015
      Atthog  40 wlltlvliivGiicitatvillvlshwerevvkyarwlgfsamvl 84 
                 + l+ +++++   c++    ll+l + + +  ++   + f+a v+
  EEA19379.1  91 LYLSAICLFMSSFCLAKVAQLLFLYRLTANQSRFRASIYFVACVI 135
                 5678899****************9999999999999999999876 PP

  == domain 2  score: 18.4 bits;  conditional E-value: 1.7e-07
      Atthog  10 aGdlrlGllktcltiygrdqvcfspelqaewlltlvliivGiicitatvillvlshwerevvkyarwlgfsamvlfclaa 89 
                   dl+l +l   l+i  +    ++ ++ a +l+ ++ +i+G i +t+tv+ll  s  +++  + a  +gf a +++ +a+
  EEA19379.1 181 ISDLTLTMLPVSLVISSQLASAYKVRIIAMMLVFFITVITGAIRLTVTVTLLHSSDETYDSAPVALLVGFEANLFILTAS 260
                 5678899999999999999999*************************************************987776665 PP

>> DUF2678  Protein of unknown function (DUF2678)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   1.3   7.5e-06     0.067      64     106 ..      94     139 ..      74     149 .. 0.79
   2 ?   -0.7   1.8      0.14   1.3e+03      34      73 ..     181     221 ..     162     239 .. 0.61

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 7.5e-06
     DUF2678  64 favcillis...ssvivlifwyrqgdlepkfrnliyyilasivllc 106
                  a+c++++s   + v  l+f yr    + +fr  iy++ + i++  
  EEA19379.1  94 SAICLFMSSfclAKVAQLLFLYRLTANQSRFRASIYFVACVIIIGP 139
                 589999875222456789**********************999855 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.14
     DUF2678  34 vgglts.llvlvtvvssfvfpslppkplniffavcilliss 73 
                 +  lt  +l +  v+ss +    + + + +++++ i +i++
  EEA19379.1 181 ISDLTLtMLPVSLVISSQLASAYKVRIIAMMLVFFITVITG 221
                 33444303334456666666666666666666665555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (289 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       868  (0.0484132); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 1984.54
//
Query:       EEA19380.1  [L=631]
Description: hypothetical protein PMAA_001750 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.9e-25   87.0   0.3    8.5e-11   42.2   0.0    4.8  5  WD40          WD domain, G-beta repeat
    2.1e-08   34.4   0.0    4.8e-06   26.8   0.0    3.0  3  ANAPC4_WD40   Anaphase-promoting complex subunit 4 WD40 domai
    0.00016   21.1   0.0    0.00027   20.3   0.0    1.3  1  WD40_like     WD40-like domain
  ------ inclusion threshold ------
      0.036   13.0   0.2       0.87    8.4   0.0    2.0  2  PALB2_WD40    Partner and localizer of BRCA2 WD40 domain
       0.08   11.9   0.0       0.98    8.3   0.0    2.2  2  Ge1_WD40      WD40 region of Ge1, enhancer of mRNA-decapping 
       0.13   11.9   0.1       0.24   10.9   0.1    1.4  1  PQQ_2         PQQ-like domain
       0.21   10.1   0.0       0.35    9.4   0.0    1.2  1  Cytochrom_D1  Cytochrome D1 heme domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0      0.62   1.6e+03      32      38 .]     114     120 ..      84     120 .. 0.79
   2 !   42.2   0.0   3.3e-14   8.5e-11       4      38 .]     261     296 ..     259     296 .. 0.94
   3 !   35.0   0.1   6.3e-12   1.6e-08       2      38 .]     301     337 ..     300     337 .. 0.94
   4 ?    2.7   0.0       0.1   2.6e+02      10      25 ..     348     365 ..     341     373 .. 0.79
   5 ?   -4.0   0.0         7   1.8e+04      26      34 ..     417     425 ..     409     426 .. 0.71

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.62
                 SEEEEEE CS
        WD40  32 gtvriWd 38 
                 +++riWd
  EEA19380.1 114 CNIRIWD 120
                 789***9 PP

  == domain 2  score: 42.2 bits;  conditional E-value: 3.3e-14
                 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 l tl+GH s+v s+afsp+g++lasGs D+tv++Wd
  EEA19380.1 261 LETLEGHeSWVQSVAFSPNGRLLASGSHDKTVKLWD 296
                 5689***999****************99*******9 PP

  == domain 3  score: 35.0 bits;  conditional E-value: 6.3e-12
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                  +++tl+ H +sv+s+afs dg++las+s D+t+++Wd
  EEA19380.1 301 ALQQTLECHeDSVCSVAFSLDGRLLASSS-DKTIKLWD 337
                 5799*****999**************999.*******9 PP

  == domain 4  score: 2.7 bits;  conditional E-value: 0.1
                 S.SS.EEEEEEETTSSEE CS
        WD40  10 H.ss.vtslafspdgawl 25 
                 H  + +t+l+fs++g++l
  EEA19380.1 348 HiEGvITDLRFSKEGPFL 365
                 665647*********996 PP

  == domain 5  score: -4.0 bits;  conditional E-value: 7
                 EEEETTSEE CS
        WD40  26 asGsdDgtv 34 
                 +s+ +Dgtv
  EEA19380.1 417 CSAVRDGTV 425
                 566679998 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.0   1.9e-09   4.8e-06      14      89 ..     240     318 ..     236     320 .. 0.82
   2 !    7.8   0.0    0.0015       3.9      40      89 ..     312     358 ..     310     361 .. 0.82
   3 ?   -2.6   0.0       2.7   6.9e+03      53      67 ..     416     430 ..     410     436 .. 0.81

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 1.9e-09
  ANAPC4_WD40  14 tedgellvfRl.ngqrvwtl...eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                   +++ l+  Rl + ++ w++   + ++++s v+s+a++p+g+lLa + +d +v+l d  +g + ++l++++++ v+++ +
   EEA19380.1 240 KSQDTLVPRRLpKVEEDWSAeleTLEGHESWVQSVAFSPNGRLLASGSHDKTVKLWDLATGALQQTLECHEDS-VCSVAF 318
                  5556666666655566677766666789999****************************************96.988876 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0015
  ANAPC4_WD40  40 evrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                  +v s+a++ dg+lLa + sd +++l d  +g + ++l+++    +t l +
   EEA19380.1 312 SVCSVAFSLDGRLLASS-SDKTIKLWDTATGALQRTLHIEGV--ITDLRF 358
                  68899*********975.899**********99998887755..666655 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 2.7
  ANAPC4_WD40  53 Lavaysdgevrllda 67 
                  L+ a+ dg+v l +a
   EEA19380.1 416 LCSAVRDGTVALGHA 430
                  889999999998776 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0   1.1e-07   0.00027       3     131 ..     271     396 ..     269     403 .. 0.88

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 1.1e-07
   WD40_like   3 iYsidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvklldddlilvvtlDGtillslleneeevenekieedistvkviddklliGtnk 101
                 + s+ +s++g l++ G++d+++++ +l ++ + + +e  edSv  v +  d  +l  + D ti l +   +   ++ +ie  i+  +  ++   + tn 
  EEA19380.1 271 VQSVAFSPNGRLLASGSHDKTVKLWDLATGALQQTLECHEDSVCSVAFSLDGRLLASSSDKTIKLWDTATGALQRTLHIEGVITDLRFSKEGPFLETNL 369
                 56899**********************************************************999999999999999999999999999999999999 PP

   WD40_like 102 GsiyvfskdlqleevllgqsseIkeikien 131
                 Gs+ +       + +++  ++ I+ ++ +n
  EEA19380.1 370 GSLSIEPS---GKSIFVEAKTRIQVLILDN 396
                 98765433...4677777777777666655 PP

>> PALB2_WD40  Partner and localizer of BRCA2 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   0.0   0.00034      0.87     196     238 ..     286     325 ..     279     331 .. 0.80
   2 ?    3.9   0.0     0.008        20     193     221 ..     324     352 ..     320     360 .. 0.89

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00034
  PALB2_WD40 196 ttvlnniviWnlktGqllkkieigesyqasvclkaysdsGllf 238
                  + ++ + +W+l+tG l +++e     ++svc  a+s  G l+
  EEA19380.1 286 GSHDKTVKLWDLATGALQQTLEC---HEDSVCSVAFSLDGRLL 325
                 44567788***********9975...679********988775 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.008
  PALB2_WD40 193 llgttvlnniviWnlktGqllkkieiges 221
                 ll+++ ++ i +W+ +tG l ++++i+  
  EEA19380.1 324 LLASSSDKTIKLWDTATGALQRTLHIEGV 352
                 8999999******************9865 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   0.0   0.00038      0.98     186     217 ..     266     298 ..     252     310 .. 0.81
   2 ?    1.1   0.0     0.061   1.6e+02     186     215 ..     310     337 ..     299     348 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00038
    Ge1_WD40 186 eh.sliveaafspdGtalatasedGevkffqvy 217
                  h s + + afsp+G  la  s+d +vk++ + 
  EEA19380.1 266 GHeSWVQSVAFSPNGRLLASGSHDKTVKLWDLA 298
                 442689999********************9875 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.061
    Ge1_WD40 186 ehsliveaafspdGtalatasedGevkffq 215
                 e+  + + afs dG  la  s+d ++k++ 
  EEA19380.1 310 ED-SVCSVAFSLDGRLLAS-SSDKTIKLWD 337
                 33.578899*****99985.6689999986 PP

>> PQQ_2  PQQ-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.1   9.6e-05      0.24      28      99 ..     273     344 ..     254     438 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 9.6e-05
       PQQ_2  28 gvsravlsggtlfva.tgggrlvaldaatGkvlWettl.egpvvgaplvaegrvvvvasdgqlialdaedGkrl 99 
                  v  a+ ++g+l++  +   ++  +d atG++  + ++ e  v++  +  +gr+++ +sd+++   d+++G ++
  EEA19380.1 273 SV--AFSPNGRLLASgSHDKTVKLWDLATGALQQTLEChEDSVCSVAFSLDGRLLASSSDKTIKLWDTATGALQ 344
                 34..6667777776647888888899999999999999888999999999999999999999999999999874 PP

>> Cytochrom_D1  Cytochrome D1 heme domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.0   0.00013      0.35      21      95 ..     254     329 ..     249     356 .. 0.88

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00013
                   ETTT-SEEEEEE-STTEEEEEE-TT.SSEEEEEETTSEEEEEESSSSSEEEEEE-SSEEE.EEEE--TTSEEEEEE CS
  Cytochrom_D1  21 dgdskeilavletgyalHisrvfasdgRyvyvigRDgkvtliDLwakeivaevkiGlnar.svavSqddryvivgn 95 
                   + d   +l++le++     s+ f+++gR++   + D +v+l DL +    ++++   ++  sva S d+r+++ ++
    EEA19380.1 254 EEDWSAELETLEGHESWVQSVAFSPNGRLLASGSHDKTVKLWDLATGALQQTLECHEDSVcSVAFSLDGRLLASSS 329
                   5666778889999999999************************************9998549********998775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (631 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       477  (0.0266049); expected 358.6 (0.02)
Passed bias filter:                      414  (0.0230911); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.61u 0.30s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 4246.60
//
Query:       EEA19381.1  [L=301]
Description: hypothetical protein PMAA_001760 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (301 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       475  (0.0264934); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.43
# Mc/sec: 2126.17
//
Query:       EEA19382.1  [L=388]
Description: isopenicillin N synthetase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.3e-20   72.1   0.0    9.1e-20   71.6   0.0    1.2  1  DIOX_N        non-haem dioxygenase in morphine synthesis N-te
    1.9e-17   63.6   0.0    6.7e-17   61.8   0.0    2.0  1  2OG-FeII_Oxy  2OG-Fe(II) oxygenase superfamily


Domain annotation for each model (and alignments):
>> DIOX_N  non-haem dioxygenase in morphine synthesis N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.6   0.0     1e-23   9.1e-20       1     117 [.      24     153 ..      24     154 .. 0.83

  Alignments for each domain:
  == domain 1  score: 71.6 bits;  conditional E-value: 1e-23
      DIOX_N   1 iPvidlspl.....sddedraavaeqlreAcrevGffyvvnhgvpeelidelfeaareFFalPeeeKeklaksp.......sfrGysrlgeektdgkkl 87 
                 +P++dlspl      +++d+ a+ ++l + ++++Gf y+vn  ++ +  +++f +a eFF+lP++eK+klak+        ++rGy ++  + td    
  EEA19382.1  24 LPIVDLSPLqspagLSESDQLALSNKLYDVFTTTGFAYLVNAPLTFK-HADVFGLALEFFNLPLDEKMKLAKKTfqpenqnTYRGYFPV--QPTDA-SD 118
                 7********999977779999***********************996.899*******************5542223455699*****6..56665.77 PP

      DIOX_N  88 dwkesfdlgtelpeddp.....agkplegpnqwPe 117
                 ++ke+f++g+e + +++     ++ +l++pn+wP+
  EEA19382.1 119 NLKEGFEIGPEQARQHSatgqeSRFHLTEPNIWPD 153
                 ***********886665544334555********8 PP

>> 2OG-FeII_Oxy  2OG-Fe(II) oxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.8   0.0   7.5e-21   6.7e-17       6      85 ..     204     306 ..     199     346 .. 0.73

  Alignments for each domain:
  == domain 1  score: 61.8 bits;  conditional E-value: 7.5e-21
                   EEEEE-S-...................-----..---EEEEEESSSEEEEEEE-TT---EEEE.TEEEE----TTEEEEEE-HHHHHHTTS-S---- CS
  2OG-FeII_Oxy   6 vlnyypph...................pdpev..ilglgahtdaslltillqddvgglevfkd.gkwlrvppvdnslivniGdallflsngryksvl 80 
                   +l +ypp+                   p+p++  +l + +htd ++lt+l+qd +gglev+++ gkw+  p v++s++vniGd + ++s+gr+  ++
    EEA19382.1 204 RLLHYPPStstsdnateiynetsgtppPEPFDpiKLSCTPHTDSGILTLLHQDATGGLEVQDSsGKWVPAPYVPESIVVNIGDLMAMVSGGRFVATM 300
                   5556688844433333333333333333333355555***********************866588******************************* PP

                   EEE-.- CS
  2OG-FeII_Oxy  81 HrVl.p 85 
                   HrV+ p
    EEA19382.1 301 HRVRaP 306
                   ***944 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (388 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       327  (0.0182386); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.25s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2520.04
//
Query:       EEA19383.1  [L=422]
Description: Zn-dependent hydrolase/oxidoreductase family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-30  106.6   0.0      1e-29  103.5   0.0    2.1  1  Lactamase_B_2  Beta-lactamase superfamily domain
    9.4e-12   45.1   0.0    6.8e-11   42.3   0.0    2.2  2  Lactamase_B_3  Beta-lactamase superfamily domain
  ------ inclusion threshold ------
       0.03   14.3   0.3        1.8    8.5   0.0    2.8  4  Lactamase_B    Metallo-beta-lactamase superfamily


Domain annotation for each model (and alignments):
>> Lactamase_B_2  Beta-lactamase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.5   0.0   1.7e-33     1e-29       2     201 .]     137     379 ..     136     379 .. 0.84

  Alignments for each domain:
  == domain 1  score: 103.5 bits;  conditional E-value: 1.7e-33
                    EEEES--TT.......HHHHHTCGGS--SSS--..SEEEEE-SS--HHHHGGGGCCCCC--EE..EEEEEEHHHHHHCCTTCGHHHCHTTTTEEEE CS
  Lactamase_B_2   2 riLiDagpd.......lrqqalralqPvelrdelppidaVllthaHyDHlaglltlrelrpkk..lplyapkgvlavleanfvylaleeepavnvh 88 
                    r+L+D++++       ++++ +r+ +P   ++e+p id+V+++h+HyDHl  l+t++++++k+   ++++p+g ++  ++ ++          nv+
     EEA19383.1 137 RVLFDPVFEdrcspfsWLGP-KRYTKPPCDVSEIPIIDMVVISHNHYDHL-SLPTVKAISKKHpnCHFFVPLGNASWFKEAGIN---------NVT 221
                    89**************99**.9998554479*******************.6******55554559999999999999999654.........556 PP

                    EE-TTSEEEE......................CSTTEEEEEEEE-EE--C.TCCE-TTTSEEEEEECTTEEEEEESS-S................. CS
  Lactamase_B_2  89 eldwgesfel......................gdggleitatparhksgr.rldrnagdtlGlriegggkrvyyigDtg................. 144
                    eldw+++ +l                      ++   +i + p +h+s+r ++dr +++++++ ie+ggk++y++gDtg                 
     EEA19383.1 222 ELDWWDERDLtlsptksgaekvtepnapategAEIVARISCLPCQHTSARgAFDRSKTLWASWGIESGGKKIYFGGDTGyrsvcglkgveddhaae 317
                    66666666666666666666666778888888667789*****************************************77777777666666665 PP

                    ....---..HHHHHHHCT-SEEEEE-S-SSTTHHHHHHT---STSHHHHCTTSSSSEEEEESB CS
  Lactamase_B_2 145 ....yip..eeigerlggadllllditayeddemirhmgHltpeeaveaaadlgakrlvliHi 201
                         +p  +++ge+ g++dl l++i+ay++++ + ++ H++p +av +++d++ k ++ +H+
     EEA19383.1 318 ynlpVCPafKQVGELRGPFDLGLIPIGAYDPRWLM-SPMHADPHDAVNIFQDTKCKNALGMHW 379
                    5444333666677999*******************.8*************************9 PP

>> Lactamase_B_3  Beta-lactamase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.3   0.0   1.1e-14   6.8e-11       3     116 ..     121     301 ..     119     307 .. 0.63
   2 ?   -0.5   0.0      0.17     1e+03     125     163 .]     332     378 ..     318     378 .. 0.85

  Alignments for each domain:
  == domain 1  score: 42.3 bits;  conditional E-value: 1.1e-14
  Lactamase_B_3   3 twlghnsfllet.agarilvDPf........kanlgyeppa................eeaDlvlisqaledHahletlkql............... 58 
                    twlgh++f  e  +g r+l DP+        +        +                + +D+v+is+++ dH  l+t+k++               
     EEA19383.1 121 TWLGHACFYAEFpGGLRVLFDPVfedrcspfS--------WlgpkrytkppcdvseiPIIDMVVISHNHYDHLSLPTVKAIskkhpnchffvplgn 208
                    9***********457********555555440........34444555666999999************************999777777777777 PP

  Lactamase_B_3  59 ............................aenvkvleegeslevg....gleiravatshdavggserge...nngflleqdgltiyhlGhlah 116
                                                ++ ++ ++e+++ + +     ++i+  + +h++  g+  +       + +e++g +iy+ G++++
     EEA19383.1 209 aswfkeaginnvteldwwderdltlsptKSGAEKVTEPNAPATEgaeiVARISCLPCQHTSARGAFDRSktlWASWGIESGGKKIYFGGDTGY 301
                    777776665555555555555555544422222333333322220112223444455555555553333112344567777777777777765 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.17
  Lactamase_B_3 125 elgrvDvvltPvgg........pltlgqeealelakrLkpklvlPmh 163
                      g+ D+ l+P+g         p+  ++++a+++ +  k k  l mh
     EEA19383.1 332 LRGPFDLGLIPIGAydprwlmsPMHADPHDAVNIFQDTKCKNALGMH 378
                    4578899999**9999999999999*******999999888888887 PP

>> Lactamase_B  Metallo-beta-lactamase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0      0.78   4.7e+03     137     162 ..      78     103 ..      75     141 .. 0.68
   2 ?   -3.6   0.0       1.5   9.2e+03       3      25 ..     122     145 ..     120     157 .. 0.79
   3 ?    8.5   0.0    0.0003       1.8      45      59 ..     172     186 ..     167     258 .. 0.73
   4 ?    2.8   0.0     0.017     1e+02     137     162 ..     285     310 ..     282     352 .. 0.79

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.78
                  EEEETTCCEEEECTTTSSHHCCCCCC CS
  Lactamase_B 137 vveygggkvlftGDallagetgridl 162
                  ++ +++ k ++tGD+  +  t+ +  
   EEA19383.1  78 SILSEMTKRVVTGDLKWPDTTPPTVT 103
                  56667778888999888666665544 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 1.5
                  CCSSEEEEEE.ETTCEEEES--SC CS
  Lactamase_B   3 pdpvnsylie.gdggviLiDtGts 25 
                  ++++ +++ e  +g  +L+D+ ++
   EEA19383.1 122 WLGHACFYAEfPGGLRVLFDPVFE 145
                  566778888877888999999765 PP

  == domain 3  score: 8.5 bits;  conditional E-value: 0.0003
                  EEEEE-SBSSHHHHT CS
  Lactamase_B  45 vdavilTHlHlDHiG 59 
                  +d v+++H H+DH +
   EEA19383.1 172 IDMVVISHNHYDHLS 186
                  788**********87 PP

  == domain 4  score: 2.8 bits;  conditional E-value: 0.017
                  EEEETTCCEEEECTTTSSHHCCCCCC CS
  Lactamase_B 137 vveygggkvlftGDallagetgridl 162
                   +e+gg+k+ f GD++++   g+ + 
   EEA19383.1 285 GIESGGKKIYFGGDTGYRSVCGLKGV 310
                  5899*************998888777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (422 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       331  (0.0184617); expected 358.6 (0.02)
Passed bias filter:                      301  (0.0167884); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.30s 00:00:00.84 Elapsed: 00:00:00.49
# Mc/sec: 2565.45
//
Query:       EEA19384.1  [L=660]
Description: C6 transcription factor (Leu3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.6e-10   39.0   9.4    1.4e-09   37.9   9.4    1.6  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.9   9.4   7.9e-14   1.4e-09       1      39 [.      15      55 ..      15      56 .. 0.88

  Alignments for each domain:
  == domain 1  score: 37.9 bits;  conditional E-value: 7.9e-14
                SS-HHHHHCT---ST....SSSS-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus  1 haCdnCrkkKvKCda....kkPaCsnCkklnleCtfysesskr 39
                +aC++Cr++K KCda    + P Cs+C+k++++C+ +s++ kr
  EEA19384.1 15 KACTECRQQKAKCDAylnpDAP-CSRCRKVGATCV-ISDPFKR 55
                59**************777777.************.7777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (660 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       945  (0.0527079); expected 358.6 (0.02)
Passed bias filter:                      700  (0.0390429); expected 358.6 (0.02)
Passed Vit filter:                        64  (0.00356964); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.71u 0.29s 00:00:01.00 Elapsed: 00:00:00.46
# Mc/sec: 4303.07
//
Query:       EEA19385.1  [L=785]
Description: small oligopeptide transporter, OPT family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.5e-184  615.1  52.7   1.8e-184  614.9  52.7    1.0  1  OPT       OPT oligopeptide transporter protein


Domain annotation for each model (and alignments):
>> OPT  OPT oligopeptide transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  614.9  52.7    1e-188  1.8e-184       2     615 ..      90     745 ..      89     746 .. 0.98

  Alignments for each domain:
  == domain 1  score: 614.9 bits;  conditional E-value: 1e-188
         OPT   2 lTlRavvlGillgvlgsavnmyfglrtglvsissipaallafplgkalarilpk.........lslnpgpftikEnvliqtmasaa..atlalatgliv 89 
                 +T+Ra+v+G++l+++gsa+nm+f++r + + i s +a+++a+p+gka+++++p+         ++lnpgpf++kE++l ++ma+a+  ++ a+at++++
  EEA19385.1  90 NTIRAWVIGLILATIGSALNMLFSMRNPYIVIPSYVAQVVAYPIGKAWEKVMPNreyslfglkFNLNPGPFSKKEHALTVIMANATfnGGAAYATDVLL 188
                 7************************************************************************************7335779******* PP

         OPT  90 vipalelygqsagfgylillslsvqllGvgfagplRkflvypeklifPsglataellkalhkpegee........ksrlkfflivflgsfvwglfplyl 180
                 +++a+  ygq+ g++  i++++s+q+lG+g+ag +++flv p+ +i+Ps l  + l++alh++++          + ++++fl+ +++sfvw++fp+++
  EEA19385.1 189 AQRAF--YGQNLGWAFEIFMCISTQMLGFGIAGFFHRFLVTPAAMIWPSVLINCSLFTALHDHRRPDpsktsgwiIGKYRLFLYTMIASFVWYWFPGFI 285
                 *****..********************************************************9988999***************************** PP

         OPT 181 fpalssfswltwiapknvvlanlf....glgllpltfdwnviaayiGsglivplwvavnmliGavlswgiliPllyysngwypaylp............ 263
                  p+ls f+w+twi p++ v+++lf    gl+l+p+tfdw++i+ +  s+li+p+  ++n+liG+v +++i+ P++ ys+ +y+ ylp            
  EEA19385.1 286 APFLSAFAWVTWIRPNSPVINQLFggwtGLSLIPITFDWTQISGFNFSPLITPWFGIANTLIGMVAWFWIVTPAIHYSKLYYSEYLPisdsnsydntah 384
                 *************************************************************************************************** PP

         OPT 264 .ydvteildedgvldyekyigyglmllaalvallylvqfaaitllivhtilkhgkdikaalksarsprteeddrhrrlmrkykdvpmwwylallvlslv 361
                  y+v++il+ d +++ +ky++y++ +l++++ l+y+++fa+i +++vht l+hgk+++ ++k++    +ee+d+h rlm + k vp wwy a+ +++++
  EEA19385.1 385 rYNVSRILNPDYTFNLQKYEEYSPLFLSTTFMLCYGLSFATIIAVLVHTGLFHGKELWIRFKTV---GKEEEDVHGRLMARFKTVPLWWYGAITLIMIG 480
                 ***************************************************************9...9******************************* PP

         OPT 362 igiivvealftqlpvwglllalllafllaivsaiiaGltglnpvsgigkltqlifgallpgrpvanlvfgavvyaaaaqagdfmqDLKtGhllkasPra 460
                 +++ v++ ++t+l++w+++++l+++ +++++++i++++t++  ++g++++t++i+g++ pgrp+a+++f++++y++++q+  f+qD+K+Gh++k++Pr 
  EEA19385.1 481 MSLGVIIGYPTHLTWWAFFVSLIICCFWFVPCGIVQATTNI--QIGLNVITEFIIGYMQPGRPMAMMLFKTYGYISMYQGLFFLQDMKLGHYMKVPPRV 577
                 *****************************************..******************************************************** PP

         OPT 461 qfvaqliGtlvgavvniavlkllvkaygdictadasnaftaPqakvfaavavl..lvggk.........kglpwafllgavapfilllllkkfpkksta 548
                 +f+aq+i++l+++vv+iav+++ + a++d+c +d++n+f++P+ +vf++++v+  ++g++         + ++w++l+ga++p+i++   + +p ks +
  EEA19385.1 578 TFAAQMISCLWCSVVQIAVMNWALGAITDVCSQDQANHFSCPNGRVFFNASVIwgVIGPQrifspgqmySNMMWFWLAGAALPVIIYFGARAWP-KSPI 675
                 ******************************************************999************99***********************.**** PP

         OPT 549 rklplplafavgfylppsl...sialligglianlwlkrrdaewakkynyvlaaGLiaGealmgviiafl 615
                 r+l+ p++f++  ++pp++   +++  i+g+++n  +++r++ w+  ynyv++aGL++G+al++++i+++
  EEA19385.1 676 RYLNAPIIFGGSALIPPATplnYLSWGIVGFVFNKFIRDRWRGWWMHYNYVFSAGLDVGLALSTILIFVA 745
                 *******************9985566888***************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (785 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       719  (0.0401026); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.66u 0.33s 00:00:00.99 Elapsed: 00:00:00.47
# Mc/sec: 4991.93
//
Query:       EEA19386.1  [L=842]
Description: serine protein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.7e-25   89.9   0.0    1.5e-24   86.8   0.0    2.1  1  Pkinase      Protein kinase domain
    6.9e-10   38.6   0.1    5.5e-05   22.6   0.0    2.5  3  Pkinase_Tyr  Protein tyrosine kinase


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.8   0.0   1.6e-28   1.5e-24       1     262 [.      37     376 ..      37     377 .. 0.84

  Alignments for each domain:
  == domain 1  score: 86.8 bits;  conditional E-value: 1.6e-28
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHS.....CTTB--EEEEEEE....SSEEEEEEE--TTEBHHHHHH CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklk.....hpnivrlyevfee....kdelylvleyveggeladlle 90 
                 y+ l+klG G++++V  a++++++   AvK+   ++++++++    +E++++++l       ++++r+++ f       ++ +lvl++v  + + +++e
  EEA19386.1  37 YRILHKLGWGGYSTVWAARDQREDTYAAVKISVAKNESEQEN----QEVHVMQTLAatqprPQHVMRMIDDFDLmgpnGRHKCLVLDLVGPN-VPEFVE 130
                 67889***************9999999999998888888776....899999998866454568888888777688889999*******976.667776 PP

                 ...HHSS--HHHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEET...................................................TT CS
     Pkinase  91 ...rkgslseeeakkiakqilegleylHskgiiHrDlKpeNiLide...................................................kg 135
                     +g l+ + ak+ia+q l gl+ lH+++i H Dl + N+ +                                                     + 
  EEA19386.1 131 phfSDGRLPGNLAKRIANQALIGLDGLHQHKIGHGDLHTRNLTFTMphlkdlqenkfmealgqpkigyvqrtdekpleagvpkyivrpavfqsqswlSH 229
                 6667899***********************************999779******************************************988888777 PP

                 EEEE-SGTTSEESSSSCSBCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHHHHHSS-STTTSSHHHH.HHHHHHTHHHHHHHCT.SHH...HHHTT CS
     Pkinase 136 elKitDFGlakelessskltsfvgtseYlAPEvlkeneyskkvDvWslGvilyelltgkppfsgekgkek.vekeldqlekilkilg.etkeklpease 232
                 e+Ki+DFG +    s    ++       +APE + + +++  vD+Ws+G++l+el+ g+ppf    ++    e +++++ ++++ +  e++e++p +s 
  EEA19386.1 230 EIKIIDFGESFLPGSI--PQTLHTPLAVRAPENIFQDSFDYRVDLWSMGCMLFELFVGQPPFDTIMKTPAiLEGQMREMANSFDAMPsESTEEIPGPSF 326
                 7*******98665554..6888889999***********************************776665314445555666666655533444444433 PP

                 S....................-HHHHHHHHHHT-SSGCCSTTHHHHHTSG CS
     Pkinase 233 i....................seeakdllkkllkkdpkkRltaeellqhp 262
                                        ++ +++ +ll+ +p++R +a+++l++p
  EEA19386.1 327 QewleemyfdsdrketlsredIVQLGEIIGRLLRFEPSSRASARDILDDP 376
                 3779999999999999987666667889******************9876 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.0   3.8e-06     0.034       3     134 ..      39     172 ..      37     188 .. 0.78
   2 !   22.6   0.0   6.1e-09   5.5e-05     163     214 ..     247     297 ..     223     321 .. 0.78
   3 ?   -3.4   0.1      0.52   4.7e+03      17      57 ..     744     785 ..     743     793 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 3.8e-06
                  EEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS..-BTTB--EEEEEE....SSSSEEEEEE--TTEBHHHHHHH CS
  Pkinase_Tyr   3 lgkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkkl..khpnivkllgvct....keepllivteyvkgGdLlkfLrk 94 
                  + +klG G +++V+ ++ +    ++++  avK+  +++++e++++ ++ ++++ ++  + +++++++        ++++ ++v+++v   ++ +f++ 
   EEA19386.1  39 ILHKLGWGGYSTVWAARDQ----REDTYAAVKISVAKNESEQENQEVHVMQTLAATqpRPQHVMRMIDDFDlmgpNGRHKCLVLDLVG-PNVPEFVEP 131
                  5689**********99988....677777888775555555444444555555444447789999998776556677779*****985.5899***99 PP

                  T.CTTTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGE CS
  Pkinase_Tyr  95 k.ekekltlkdllsfalqvAkGmeyLeskklvHrdlaarNv 134
                  + ++ +l  +   ++a q   G++ L+++k+ H dl +rN 
   EEA19386.1 132 HfSDGRLPGNLAKRIANQALIGLDGLHQHKIGHGDLHTRNL 172
                  95667788888889999999********************7 PP

  == domain 2  score: 22.6 bits;  conditional E-value: 6.1e-09
                  TSSTSGGGGS-HHHHHHSEEEHHHHHHHHHHHHHHHHTTSSGTTTTSHHHHH CS
  Pkinase_Tyr 163 eeaklpvkWmapEslkekkftsksDvWsfGvllwEiftlgespypglkneev 214
                  ++ ++p+   apE +++ +f  + D Ws G +l+E+f  g+ p+ +++++ +
   EEA19386.1 247 QTLHTPLAVRAPENIFQDSFDYRVDLWSMGCMLFELFV-GQPPFDTIMKTPA 297
                  4556788889***************************9.*****99966544 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 0.52
                  EEEEETTTTSSEEEEEEEEESTTSSHHHHHHH.HHHHHHHHT CS
  Pkinase_Tyr  17 egtlkgekekkevkVavKtlkeeateeekeel.leeakimkk 57 
                   g+++g+ ++++ k a+ +l++++++++ +++ + +a++m++
   EEA19386.1 744 DGHWTGSGTQEDRKAALEQLTRRKRHHSLRNItVADAHMMND 785
                  578888899999999999998777777655541557777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (842 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       541  (0.0301746); expected 358.6 (0.02)
Passed bias filter:                      514  (0.0286686); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.70u 0.28s 00:00:00.98 Elapsed: 00:00:00.45
# Mc/sec: 5607.78
//
Query:       EEA19387.1  [L=118]
Description: hypothetical protein PMAA_001820 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (118 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       380  (0.0211947); expected 358.6 (0.02)
Passed bias filter:                      299  (0.0166769); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.44
# Mc/sec: 798.70
//
Query:       EEA19388.1  [L=326]
Description: ketopantoate reductase family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.3e-33  113.4   0.0    9.5e-33  113.0   0.0    1.1  1  ApbA      Ketopantoate reductase PanE/ApbA
    4.3e-27   94.8   0.0    6.7e-27   94.2   0.0    1.3  1  ApbA_C    Ketopantoate reductase PanE/ApbA C terminal


Domain annotation for each model (and alignments):
>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.0   0.0   1.1e-36   9.5e-33       1     151 [.       9     160 ..       9     161 .. 0.97

  Alignments for each domain:
  == domain 1  score: 113.0 bits;  conditional E-value: 1.1e-36
                 EEEES-SHHHHHHHHHHHH.HTHCEEEE-SCHHHHHHHHHCEEEEETT.CEEEEEECEEECCHSCCCCS-ESEEEE-SSGGGHHHHHHHHGGGECTC.E CS
        ApbA   1 iailGaGaiGsllaakLak.agadvtlilrsrrlealkknGlrltseg.geeilrppealsaeekselepidlvivtvKayqteealeeikplldpn.t 96 
                 +++ G+GaiGs++a  L++  +    +++rs+ ++a+k nGl ++s + g++++ p++++ ++  + ++ +d+++ + Ka + ++a+++i+p++d++ t
  EEA19388.1   9 VLVYGLGAIGSFYAFILSRnPNVRLSVVARSN-YDAVKANGLIIDSQNhGKHTVVPEKVFKTP-AEAGQTYDYIVCAHKAIDQDAAVKAIAPAVDEDsT 105
                 689****************88889********.***************9*********99999.99******************************988 PP

                 EEEEESSSSCHHHHHTTTSTTSEEEEEEEE-EEEEEETTEEEECS--EEEEEESS CS
        ApbA  97 vvlllqNGlgheeelrealpkprvlggvtthgatregpgevhhagkgeikigela 151
                 + +++qNG+g+ee++r + pk++++ +vt+ gat+++pg v+h+ +++++ig ++
  EEA19388.1 106 ALVIIQNGVGNEEPFRNEWPKATIITCVTWTGATQTSPGYVNHTKNEDMQIGLFP 160
                 9***************************************************886 PP

>> ApbA_C  Ketopantoate reductase PanE/ApbA C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.2   0.0   7.4e-31   6.7e-27       3     122 ..     194     314 ..     192     317 .. 0.93

  Alignments for each domain:
  == domain 1  score: 94.2 bits;  conditional E-value: 7.4e-31
      ApbA_C   3 rlarweKllinaainpltalldckngell.espelralvrallkEalavaeaegvelseerleeaveavlektaanrsSMlqDveagrktEidyinGav 100
                  l rweK+++naa+n+lt  + ++++  l +spe+  + r+l+ E+++v +a+gv+  e +l ++  + + ++++  sSM+ D  agr++E+d+i+G++
  EEA19388.1 194 PLQRWEKVVWNAAWNSLTSATLLDTHSWLaSSPEATPMTRRLMSEVIDVGRACGVSTLEYSLIDQFIERILAMPPIGSSMRTDTVAGRPLEVDVILGYP 292
                 578**********************77666**************************66666999999999999************************** PP

      ApbA_C 101 vklAeklgvetPvnellyellk 122
                  k  ++l+++tP+++++y+++ 
  EEA19388.1 293 YKKSKELKLSTPTLDAIYAVVM 314
                 *******************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (326 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       444  (0.0247643); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2338.71
//
Query:       EEA19389.1  [L=489]
Description: cytochrome B2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   9.5e-111  370.2   0.6   1.2e-110  369.9   0.6    1.1  1  FMN_dh        FMN-dependent dehydrogenase
    2.4e-22   78.9   0.0    1.5e-21   76.3   0.0    2.2  2  Cyt-b5        Cytochrome b5-like Heme/Steroid binding domain
    1.9e-06   27.3   0.1    3.3e-06   26.5   0.1    1.3  1  Glu_synthase  Conserved region in glutamate synthase
    1.5e-05   24.2   1.3      6e-05   22.2   0.5    2.0  2  IMPDH         IMP dehydrogenase / GMP reductase domain
    0.00081   18.9   1.0     0.0012   18.3   1.0    1.3  1  NMO           Nitronate monooxygenase
  ------ inclusion threshold ------
      0.063   12.6   0.1        1.2    8.4   0.0    2.2  2  ThiG          Thiazole biosynthesis protein ThiG


Domain annotation for each model (and alignments):
>> FMN_dh  FMN-dependent dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  369.9   0.6  3.9e-114  1.2e-110       1     347 [.     128     474 ..     128     475 .. 0.92

  Alignments for each domain:
  == domain 1  score: 369.9 bits;  conditional E-value: 3.9e-114
                 HHCCS-HHHHHHHH--STTSHHHHHHHHGGGGEEE---SSSS-SS-B--EEETTEEESSSEEE--BSTGGGTSTTHHHHHHHHHHHHTS-EEEETT-SS CS
      FMN_dh   1 ArkrlpkkafayvaggagdevtlrenraaferirlrprvlrdvskvdlsttllGqklslPvliaPvglaklahpdgelalaraaakagipfvlstvast 99 
                 A++ l ++a+ay++ ga+de +++e + a++++ lrpr+lrdvsk+d+st++lG+++slP++i++vg+ak+ahp ge++la aa + gi + + t +s+
  EEA19389.1 128 AERYLAENAWAYYTAGADDEYSKAEAELAYRKVLLRPRILRDVSKIDTSTQILGHDVSLPIYISAVGIAKFAHPLGECILAAAAGHEGIAQLCATRSSM 226
                 789999********************************************************************************************* PP

                 -HHHHHH....HHTT-EEEEEE-CSSHHHHHHHHHHHHHCTESEEEEESSTSS---BHHHHHCT--BSTT-T.G.TTGGGSTSGSCCTTH..THHHHHH CS
      FMN_dh 100 sleevaa....aaegplwfqlyvpkdrelteellkraeaagykalvltvDtpvlgkRerdlrngfslppklklrnllqelakpewaaealkkasaaaef 194
                 s+e +++      e+p +fqly++kd +++e+ + +a +ag+k ++ltvD pv+gkRerd+r++ ++  + + +n+  + +            ++ a+ 
  EEA19389.1 227 SIESIMKtrtgGPEQPIFFQLYMHKDAKISEATILKAVKAGVKGIWLTVDSPVTGKRERDERVKATVDVGEQNDNIGGKGQPV----------QGVAKT 315
                 *******53221335************************************************88888884433322222222..........333355 PP

                 CCCHB-TC--HHHHHHHHHHHSSEEEEEEE-SHHHHHHHHHTTESEEEE--GGGTSSTT---HHHCHHHHHHHH.......SS-EEEESS--SHHHHHH CS
      FMN_dh 195 vgkqldpsltwddikwlreqtklplvvKGvltaedakraveaGvdgivvSNHGGRqldgapatidvLpeiveavgg.....rievlvDgGirrGsDvlk 288
                 +++++ p l+w++i+ +r+ t+lplv+KG++++eda +a ++ vdgiv+SNHGGR+ d+a+a++ +L ei +++++     ++++++DgG+rrG+Dv+k
  EEA19389.1 316 LASTVAPYLDWNTISYIRKLTDLPLVIKGIQSVEDAVLAHKHKVDGIVISNHGGRSQDTAQAPLLTLLEINKYAPHiikdkKMQIFIDGGVRRGTDVVK 414
                 688899****************************************************************999975555558***************** PP

                 HHHTT-SEEEESHHHHHHHH.HHHHHHHHHHHHHHHHHHHHHHHHHT-SBHHHHHCGGEE CS
      FMN_dh 289 AlalGAdavllGRpflygla.agGeeGvervleilraelertmallGvksvaeldrslls 347
                 AlalGA+av++GRpfly +a  +Ge+G +r++ i+r+e+e++mal+Gv++++el+r+ll+
  EEA19389.1 415 ALALGATAVGMGRPFLYSMAsGYGEAGTRRMIGIMREEIEQNMALVGVTKISELRRELLN 474
                 ******************87358**********************************997 PP

>> Cyt-b5  Cytochrome b5-like Heme/Steroid binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.3   0.0   5.1e-25   1.5e-21       3      73 ..      13      83 ..      11      84 .. 0.93
   2 ?   -0.6   0.0      0.52   1.5e+03      32      48 ..     200     216 ..     193     235 .. 0.80

  Alignments for each domain:
  == domain 1  score: 76.3 bits;  conditional E-value: 5.1e-25
                HHHTTTECTTEEEEEETTEEEECTTTCCCSTTCSHHHHTTTTSBBHHHHHHTTGGCHHHHHHHHG.GEEEEE CS
      Cyt-b5  3 eelskhngkndlwvairgkVYDvskflskhpGgesailkyaGkDateafksvvhsekdaekllkk.ylvGkl 73
                ee+++hn+k+++w+a+rgkVYD+++fl++hpGg+ +ilk aG+Dat++  ++ h  + +e+ l +  ++G++
  EEA19389.1 13 EEVAQHNNKESCWIAVRGKVYDITDFLDEHPGGARVILKCAGRDATDDYDAI-HPAELIEETLPAsAFKGTV 83
                8***************************************************.8888789988888888876 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.52
                 STTCSHHHHTTTTSBBH CS
      Cyt-b5  32 hpGgesailkyaGkDat 48 
                 hp ge ++ ++aG+   
  EEA19389.1 200 HPLGECILAAAAGHEGI 216
                 9************9655 PP

>> Glu_synthase  Conserved region in glutamate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.5   0.1   1.1e-09   3.3e-06     226     310 ..     357     433 ..     328     437 .. 0.76

  Alignments for each domain:
  == domain 1  score: 26.5 bits;  conditional E-value: 1.1e-09
                   TT-SEEEEE-TT---SSEEHHHHHHB---HHHHHHHHHHHHHHTT-GGG-EEEEESS--SHHHHHHHHHHT-SEEE-SHHHHHHT CS
  Glu_synthase 226 anadiilidGleGGTGAspkssikhaGlPlelalaevdqtlkeeglrdrvsliadGglktgadvvkalalGAdavgigtaalial 310
                    ++d i+i+ + G        s ++a  Pl+  l e+++   +    +++++++dGg++ g+dvvkalalGA avg+g+  l ++
    EEA19389.1 357 HKVDGIVISNHGG-------RSQDTAQAPLL-TLLEINKYAPHIIKDKKMQIFIDGGVRRGTDVVKALALGATAVGMGRPFLYSM 433
                   5555555554433.......45566666654.46666777777777889******************************999887 PP

>> IMPDH  IMP dehydrogenase / GMP reductase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.2   0.5     2e-08     6e-05     202     239 ..     392     429 ..     385     446 .. 0.85
   2 ?   -0.4   0.0      0.15   4.4e+02     301     328 ..     444     471 ..     438     479 .. 0.85

  Alignments for each domain:
  == domain 1  score: 22.2 bits;  conditional E-value: 2e-08
                 HHCTCT-EEEEES---SHHHHHHHHHTT-SEEEESCCC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       IMPDH 202 aakkagvpviaDGGikysgdivkAlaaGadavmlGsll 239
                 + k++++++  DGG++   d+vkAla+Ga av +G+ +
  EEA19389.1 392 IIKDKKMQIFIDGGVRRGTDVVKALALGATAVGMGRPF 429
                 5678899****************************854 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.15
                 HHHHHHHHHHHHHHHHHT-SSHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       IMPDH 301 evveqlvgglrsgmgylGaktieelkek 328
                 +++  + +++ + m  +G+++i+el+++
  EEA19389.1 444 RMIGIMREEIEQNMALVGVTKISELRRE 471
                 67778889999**************975 PP

>> NMO  Nitronate monooxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   1.0   4.2e-07    0.0012     110     239 ..     313     443 ..     249     463 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 4.2e-07
         NMO 110 ldekvevvsfgfglpteevvarlkeagvvliptissvkearkvearGaDalivqGpeaGGhqGtpevgd....kglfaLvpqvldavdiPviAaGGiid 204
                 +++ +  v   ++ +t   + +l ++  ++i  i sv++a  + +   D +++  ++ GG   + + +      +  +  p++ +  ++ +   GG+ +
  EEA19389.1 313 AKTLASTVAPYLDWNTISYIRKLTDLP-LVIKGIQSVEDAVLAHKHKVDGIVI--SNHGGRSQDTAQAPlltlLEINKYAPHIIKDKKMQIFIDGGVRR 408
                 555555555556666666666666655.5688999***************999..588998885555433223333333445555555*********** PP

         NMO 205 rrgvaaaLalGAsgvqigtrfLltkesdakdahkk 239
                 + +v  aLalGA +v +g  fL    s+  +a  +
  EEA19389.1 409 GTDVVKALALGATAVGMGRPFLYSMASGYGEAGTR 443
                 **********************9888876666555 PP

>> ThiG  Thiazole biosynthesis protein ThiG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0     0.046   1.4e+02     166     212 ..     328     373 ..     318     378 .. 0.84
   2 ?    8.4   0.0   0.00041       1.2     169     201 ..     391     423 ..     383     428 .. 0.88

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.046
                 HHHHHHHH-SS-BEEES---SHHHHHHHHHTT-SEEEESHHHHTSSS CS
        ThiG 166 alkiiieeakvPvivDAGigspsdaaqamelGadavllntavaeakd 212
                 +++ i++ +++P+++  Gi s +da+ a +  +d++++     +++d
  EEA19389.1 328 TISYIRKLTDLPLVIK-GIQSVEDAVLAHKHKVDGIVISNHGGRSQD 373
                 678899999****995.******************999876666665 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.00041
                 HHHHH-SS-BEEES---SHHHHHHHHHTT-SEE CS
        ThiG 169 iiieeakvPvivDAGigspsdaaqamelGadav 201
                  ii++ k+ + +D G+++ +d+++a+ lGa+av
  EEA19389.1 391 HIIKDKKMQIFIDGGVRRGTDVVKALALGATAV 423
                 577888999**********************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (489 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       402  (0.0224218); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 3223.18
//
Query:       EEA19390.1  [L=507]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    9.3e-12   45.1  16.4    9.3e-12   45.1  16.4    3.8  3  Beta_helix  Right handed beta helix region


Domain annotation for each model (and alignments):
>> Beta_helix  Right handed beta helix region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.8   4.3   0.00015       2.7      52     115 ..     100     175 ..      17     182 .. 0.64
   2 !   45.1  16.4   5.2e-16   9.3e-12      12     157 ..     134     319 ..     101     320 .. 0.79
   3 !    3.2   1.6     0.004        72      85     115 ..     400     437 ..     358     478 .. 0.67

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.00015
                 -TT-S-EEES-EE.....E---SEEE-TT--S--EEES-EEES-SS-.....SEE-TT......-S--EEES-EEESTT- CS
  Beta_helix  52 lgssnntisnnti.....sdnngggialfgasnnlienneitdnggs.....Giylny......ssnntienNiidnnag 115
                 l+++n+++++ +      +d++   i l +asn +   n +++n+++      i   +      ++n+ti+nN i  +++
  EEA19390.1 100 LRVKNIQFDGLRPslglvEDGG-ATIELGQASNGIEISNIMSRNSRAwsclhLI---QggadtpCTNVTISNNKIGPCGN 175
                 3332333322222122214444.7888888888888888888885555533322...12334668888888888766664 PP

  == domain 2  score: 45.1 bits;  conditional E-value: 5.2e-16
                 EEESEEEES-.SS-SEEE-SSS-.......EEES-EEES............-SS-SEEE-TT-S-EEES-EEE---SEEE-TT--S--EEES-EEES-S CS
  Beta_helix  12 tiknntisns.ggyGiylrgssn......vvienneian............nsgsGiyilgssnntisnntisdnngggialfgasnnlienneitdng 91 
                 +i+n   +ns  +++++l +++       v+i+nn+i              ++ +Gi+  +  ++ i+nn+i+++++ggi lfga ++++++n+i+   
  EEA19390.1 134 EISNIMSRNSrAWSCLHLIQGGAdtpctnVTISNNKIGPcgneghnsagvpQWADGISFAC-RDSLIENNYIEGSTDGGIVLFGAPGTTVQGNTIISST 231
                 33333333337788888888888889999********995555555666666666666655.***********************************95 PP

                 S-....SEE-TT......-S--EEES-EEESTT..--SEE---TT..........---EEES-EEES-SSEEEE-TT-SS--EEES-E CS
  Beta_helix  92 gs....Giylny......ssnntienNiidnna..gsGividdss..........snvtvtnNtitnnkgaGiavvgsssnvtvrnNt 157
                 ++     i++ +        n++++nN+i + +  + Gi i + +             tvtnN i++n   +i v+g+ +++tv++N 
  EEA19390.1 232 TDsgfgAINMVDylydgsYANVVVTNNTIIGQKmfNTGIAIGAFAwsfnddvflqGPATVTNNLISGNIPFAIGVNGWTGGLTVTGND 319
                 555555666664688887788999***********5555554444446777777767789**************************97 PP

  == domain 3  score: 3.2 bits;  conditional E-value: 0.004
                 -EEES-SS-SEE-TT.-S--EEES-EEESTT......- CS
  Beta_helix  85 neitdnggsGiylny.ssnntienNiidnna......g 115
                 n++  n  + i ++y  +nn++++N+ ++ +      g
  EEA19390.1 400 NTVLANLHNSIITQYqGDNNIVTYNTSTGDYvavwssG 437
                 55555555555555335556666666655553333331 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (507 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       499  (0.027832); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 3330.68
//
Query:       EEA19391.1  [L=426]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      1e-14   55.7   0.0    1.5e-14   55.2   0.0    1.3  1  Abhydrolase_6  Alpha/beta hydrolase family
    7.5e-06   25.4   0.0    1.5e-05   24.4   0.0    1.5  1  Hydrolase_4    Serine aminopeptidase, S33
    2.7e-05   23.9   0.0    9.8e-05   22.1   0.0    1.8  1  Abhydrolase_1  alpha/beta hydrolase fold
  ------ inclusion threshold ------
      0.017   13.9   0.0      0.023   13.4   0.0    1.2  1  Ndr            Ndr family


Domain annotation for each model (and alignments):
>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.2   0.0   3.3e-18   1.5e-14       2     219 ..      55     369 ..      54     370 .. 0.56

  Alignments for each domain:
  == domain 1  score: 55.2 bits;  conditional E-value: 3.3e-18
                    EEE--GC.....G.C..HHHHHHHHCCT.....CEEEEE--TTS...T.......S-GGCS--HHHCHHHHHHHCCTT...TTSEEEEEETCH.HH CS
  Abhydrolase_6   2 lllHGagssassW.l..vapLaallaag.....vhvlapDlpGh...G.......rsdpppldledladlaalldelaa.gggpvvlvGHSlG.Ga 77 
                    + +HG+g++++++     + L +l a+g     +  ++ D   +   G       ++dp+++d+  ++dl+ l++ ++a  ++p+v+vGHSlG G 
     EEA19391.1  55 IGAHGSGFPKEMYePiwEGVLSRLNAQGvrvrsI--WIADNATQsasGvlneeylGNDPSWFDH--ARDLLYLINYFKAdMPRPIVGVGHSLGaGQ 146
                    668******9999524455778888888776666..99***98865557777777779999999..9**********99999999********766 PP

                    HHHH.HHHCC...EE.EEES-....----TTT...........S----TTHHHHHHTT-C....CCCHCCH......S-HSCCCCHHH..CCCCHC CS
  Abhydrolase_6  78 lala.aapla.lvvg.vlldp..pptalpagl...........laaalelllallallrl....lawlsre......plprlfladed..adaawr 145
                    lal+ ++ ++ l+ + vl++p       p+++           l++   ++ +l a+  +      w+ r+      +  r+ l+++d  +  a++
     EEA19391.1 147 LALLsLL-HPrLLTSlVLMEPviE----PDTFsakgptfvklsLNRKDMWPSQLEAAKDFkkayRKWDPRAieryikYGLRDVLPETDstKTGAVT 237
                    8888322.44455558*****551....33333333333444433333333333332222333445553333344453333555555544122222 PP

                    HCCCGHH..........................................HHCCHHCHTTCCHHTT-TTGC...........EEE.CTT-CHHHHCH CS
  Abhydrolase_6 146 arlarla..........................................allaglgllpaaawadlpvpl...........lvl.ggeDplvprll 187
                     + +r++                                                    ++ ++  pv+l           l l g++ p+  +  
     EEA19391.1 238 LTTSRHQevvqymrpnfhnkkpldadndpeslqfhdtvfypdtmgpsnsI---------YPFYRCEPVLLfkllkhirpsvLYLyGESSPISTPDN 324
                    22222223334444555555555555555555444444333322222220.........2233333333344444334433666568888666443 PP

                    HCCCH.STTEEET............CE...SSS.-HHHHSHHHHHH CS
  Abhydrolase_6 188 erlla.qagarlp............vvlpgaGH.lphleepdevae 219
                    +++   ++g++++            v++pgaGH lp++ + d v +
     EEA19391.1 325 RARKLeRTGKGIGgsggykngrvkeVTFPGAGHaLPFE-AVDGVSD 369
                    3333355777775778888999999********55554.6588776 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4   0.0   3.3e-09   1.5e-05      46     159 ..     100     217 ..      53     231 .. 0.80

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 3.3e-09
  Hydrolase_4  46 e....gkrghvpsfddyvdDlaafvekvkeehpelplfllGhSmGGliallyllrypdkvaglilsaPalkikaklk.appllklllkllgkllpklq 138
                  +       g  ps+ d+ +Dl  +++ +k++ p+ p++ +GhS+G+   +l+ l +p+ ++ l+l+ P++++++     p ++kl l+       +l+
   EEA19391.1 100 GvlneEYLGNDPSWFDHARDLLYLINYFKADMPR-PIVGVGHSLGAGQLALLSLLHPRLLTSLVLMEPVIEPDTFSAkGPTFVKLSLNRKDMWPSQLE 196
                  5555456677799****************98886.69***********************************98776799999988877777666777 PP

  Hydrolase_4 139 vsnnlkadslsrdpevvaaye 159
                    +  k+++   dp+ +++y 
   EEA19391.1 197 AAKDFKKAYRKWDPRAIERYI 217
                  777777777777888888775 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.1   0.0   2.2e-08   9.8e-05      73     255 ..     133     362 ..      94     364 .. 0.78

  Alignments for each domain:
  == domain 1  score: 22.1 bits;  conditional E-value: 2.2e-08
                    SSEEEEEETHHHHHHHHHHHHHGGGEEEEEEESE.........................CSSCCHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHH CS
  Abhydrolase_1  73 dkltlvGhSmGGmialayaaeyperVkalvllga.........................idpaaslieaqrqqaksfpdffdgyaadcarnpagpl 143
                    ++++ vGhS+G  + + + +++p    +lvl+++                         ++   +  + ++ ++k++p++ ++y+  + r ++   
     EEA19391.1 133 RPIVGVGHSLGAGQLALLSLLHPRLLTSLVLMEPviepdtfsakgptfvklslnrkdmwPSQLEAAKDFKKAYRKWDPRAIERYIKYGLRDVLPET 228
                    466789**************************************************66666666666777889*********************** PP

                    HHCCSCHHHHHHHHHHHHHH...........HCHHHCCHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHCTHHHHSEEEEEEETTCSSSCH. CS
  Abhydrolase_1 144 ladelaaleqrhrlvdalkf...........pdkskrfpssgsdnasslatgalksieqwpttdsaklllrlrelknvlaptlvisgtsDplvpp. 227
                     + + +a+++ ++ + + ++            d + +++s  + + +    +   s + +p + + ++ll+   lk +   +l+++g+s p+ +p 
     EEA19391.1 229 DSTKTGAVTLTTSRHQEVVQymrpnfhnkkpLDADNDPESLQFHDTVFYPDTMGPSNSIYPFYRCEPVLLFKL-LKHIRPSVLYLYGESSPISTPd 323
                    **************99888888777776665333333333333333333333333333333333333333333.5777779999************ PP

                    HHHHHHHHC..........HTS.EEEEEEETCSSSHHHH CS
  Abhydrolase_1 228 kaledlaql..........lpk.krlvvisdagHlafle 255
                    +  ++l++            ++ +++v++++agH + +e
     EEA19391.1 324 NRARKLERTgkgiggsggyKNGrVKEVTFPGAGHALPFE 362
                    ********999988877764448***********99887 PP

>> Ndr  Ndr family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   5.2e-06     0.023      80     134 ..     111     168 ..      95     218 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 5.2e-06
                 --HHHHHTTHHHHHHHHT---...EEEEEETHHHHHHHHHHHHSGGGEEEEEEES--- CS
         Ndr  80 pslddladqllavldhfklks...viglGvgaGAyilarfalkhperveglvLinits 134
                 ps  d a +ll ++++fk +    ++g+G   GA  la+ +l hp ++++lvL+++  
  EEA19391.1 111 PSWFDHARDLLYLINYFKADMprpIVGVGHSLGAGQLALLSLLHPRLLTSLVLMEPVI 168
                 777788999999*****98644449*****************************9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (426 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       547  (0.0305092); expected 358.6 (0.02)
Passed bias filter:                      495  (0.0276089); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 2866.81
//
Query:       EEA19392.1  [L=482]
Description: class V chitinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.4e-52  177.2   0.0      1e-51  176.5   0.0    1.2  1  Glyco_hydro_18  Glycosyl hydrolases family 18
    6.6e-13   48.9  32.5    2.4e-10   40.7  11.5    2.5  2  Chitin_bind_1   Chitin recognition protein
  ------ inclusion threshold ------
       0.35   10.2   3.3        0.6    9.5   3.3    1.3  1  Ciart           Circadian-associated transcriptional represso


Domain annotation for each model (and alignments):
>> Glyco_hydro_18  Glycosyl hydrolases family 18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  176.5   0.0   1.7e-55     1e-51      16     275 ..     176     461 ..     160     481 .. 0.86

  Alignments for each domain:
  == domain 1  score: 176.5 bits;  conditional E-value: 1.7e-55
                     C...SHTTTESEEEEEEEEEEETTTEEEESSTTHHHHHHHHHHHHHHTSTT-EEEEEEEETTTTT.......HHHHHHTSHHHHHHHHHHHHHHH CS
                     x...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18  16 y...lpsaklthiiyaFakidgengkvvvsdwedlgnfeqlkklkkkknpgvkvllsiGGwtdss.......gfslaastdasrkkfadsvvsll 100
                     y   l+ ++++h+++aFa +d+++ +v    ++d+  + ++++lk   npg+ +++siGGw+ ++       +fs++a++  ++++f +s+v ++
      EEA19392.1 176 YpedLQMTAYSHLNFAFAFVDPKTFEVAPMSEGDTALYPRFTALK-TYNPGLETWISIGGWSMNDpdqptatTFSDLAGSGSAQTAFFQSLVHFM 269
                     244577899*************99999988899999*********.****************9667789999*******99************** PP

                     HHCT-SEEEEEES-TTTS.....TCHHHHHHHHHHHHHHHHHHHHHHTSTTCEEEEEEESSHHHHHHHCHHHHHHHHTSEEEEETTTSSSTTSS. CS
                     xxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx. RF
  Glyco_hydro_18 101 rkygfDGiDidweypggn.....pedkenytallkelrealdkakategkkllLsaavpasasdlskgydlpkiakylDyvnvmtYDfhgswdn. 189
                      +yg+DG+Didweyp +      p+d +ny+ +lk+lr a+++     g k+ Ls+++p+s+++++++ d++ i  ++D++nvmtYD+hg wd+ 
      EEA19392.1 270 STYGLDGVDIDWEYPVAPersgkPADFANYVSFLKKLRDAFGA----GGHKYGLSITLPSSYWYMQNF-DIKSIEPVVDWFNVMTYDLHGIWDSt 359
                     **************8776888999***************9995....489**************8888.*********************99999 PP

                     ......BE--SS-SSBTCSSHHHHHHHHHHTT--GGGEEEEEESEEEEEEESSSSSS...............TSTTTEEEHHHHHHHHTEEEEEE CS
                     ......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...............xxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18 190 ......vtghhaplydaslnvdeavkeylkagvpakklvlGvpfygrawalvsgadn...............tkeegvlsykelkellkkakakr 263
                           v++ h++l      +d++++ + +++++++k+v+G+ fygr+++l++++ n                 ++g+l y+e+ +   +++a++
      EEA19392.1 360 dpyigsVINAHTNL----TQIDQTLDLLWRNQIDPSKVVMGMGFYGRSFTLADPSCNttgcpfpgggnagpcSASSGTLMYSEIGDI-LANGATV 449
                     9999999*******....99999997666889********************997668888888889999999999*******9996.5566777 PP

                     EEETTTTEEEEE CS
                     xxxxxxxxxxxx RF
  Glyco_hydro_18 264 kydskakapyvy 275
                     + d++a++  v 
      EEA19392.1 450 VEDKTAGVAIVT 461
                     777777776652 PP

>> Chitin_bind_1  Chitin recognition protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5  13.0   1.3e-05     0.078      15      38 .]      90     114 ..      74     114 .. 0.81
   2 !   40.7  11.5     4e-14   2.4e-10       6      36 ..     129     165 ..     123     166 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 1.3e-05
                    -EE-TTSBEEBSHHHHSTT.--BS- CS
  Chitin_bind_1  15 vCCSqyGyCGttsdyCgag.CqsnC 38 
                     CCS+ G CG ++++C+   C s+C
     EEA19392.1  90 GCCSNTGVCGLGPKFCSPDvCISSC 114
                    4***************8668***99 PP

  == domain 2  score: 40.7 bits;  conditional E-value: 4e-14
                    CTT---STT-EE-TTSBEEBSHHHHSTT......--B CS
  Chitin_bind_1   6 aggatCplnvCCSqyGyCGttsdyCgag......Cqs 36 
                    + ++ CplnvCCSqyG+CGttsd+Cg++      C s
     EEA19392.1 129 SSNEACPLNVCCSQYGFCGTTSDFCGNTtvkqpsCSS 165
                    37899********************654443345665 PP

>> Ciart  Circadian-associated transcriptional repressor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   3.3    0.0001       0.6     153     262 ..       8     122 ..       3     129 .. 0.77

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.0001
       Ciart 153 qkqplhltewpalnltwihttpicnpplsslGsasf..shg.llGtgtsiGvilflqkGaqsfahsapttpvpaatvspvv..sddpkklseeeprcys 246
                 +k+ + +t +p l l w+ht p+         + s+  s g l+ ++  i v  +l   + s a  + + p   +++sp    +     + + +p+  s
  EEA19392.1   8 RKNGFDITPFPILTLCWLHTKPVIASLDLGYRTCSYtrSFGsLILSSKFIAVCAILSSIVSSAASDSAADPYSCSATSPCKigCCSNTGVCGLGPKFCS 106
                 667788999*************987654444455541155514556777899999*********999***********975125566678999999999 PP

       Ciart 247 lpvtlasdrsctlssp 262
                   v+++s  +++ + p
  EEA19392.1 107 PDVCISSCDAKSECDP 122
                 9999998777777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (482 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       488  (0.0272185); expected 358.6 (0.02)
Passed bias filter:                      249  (0.0138881); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 3169.60
//
Query:       EEA19393.1  [L=537]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.9e-25   86.3   0.5    1.1e-08   35.0   0.1    3.4  3  LysM      LysM domain


Domain annotation for each model (and alignments):
>> LysM  LysM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.0   0.1   5.9e-13   1.1e-08       1      44 []     228     272 ..     228     272 .. 0.97
   2 !   30.0   0.0   2.2e-11     4e-07       1      43 [.     278     322 ..     278     323 .. 0.98
   3 !   17.9   0.0   1.3e-07    0.0023       1      31 [.     432     464 ..     432     472 .. 0.84

  Alignments for each domain:
  == domain 1  score: 35.0 bits;  conditional E-value: 5.9e-13
                 EEE-TT--HHHHHHHCTCHHHHHHHHCTCSSCG.G--TTEEEEEE CS
        LysM   1 YtVkkGDTLwsIAkrygitveklleaNnlsspd.kifpGqkLkiP 44 
                 Y V +GD + +IA +++++  +l++ N ++s+  +i++Gq+L+ P
  EEA19393.1 228 YNVVSGDNCQAIAEQNSVSTGTLIAINDIYSDCtNIWVGQVLCMP 272
                 88***************************999899********98 PP

  == domain 2  score: 30.0 bits;  conditional E-value: 2.2e-11
                 EEE-TT--HHHHHHHCTCHHHHHHHHC...TCSSCGG--TTEEEEE CS
        LysM   1 YtVkkGDTLwsIAkrygitveklleaN...nlsspdkifpGqkLki 43 
                 Y+V++GDT+ +IA+  ++ ++kl ++N   + ++++ +  Gq +++
  EEA19393.1 278 YIVQSGDTCDGIAATTNTMFQKLVAWNpalGSYCTN-LLSGQNICV 322
                 99**********************************.*******98 PP

  == domain 3  score: 17.9 bits;  conditional E-value: 1.3e-07
                 EEE-TT--HHHHHHHCTCHHHHHHHHC..TCSS CS
        LysM   1 YtVkkGDTLwsIAkrygitveklleaN..nlss 31 
                 Y++++GD +  + +r++it+ +l+++N   ls+
  EEA19393.1 432 YVIQSGDYCALVENRFDITMAQLQAWNfsLLSD 464
                 9**************************864444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (537 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       584  (0.0325729); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 3494.70
//
Query:       EEA19394.1  [L=446]
Description: hypothetical protein PMAA_001890 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (446 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       780  (0.0435049); expected 358.6 (0.02)
Passed bias filter:                      476  (0.0265492); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3103.29
//
Query:       EEA19395.1  [L=450]
Description: O-methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-15   57.3   0.0    3.4e-15   55.9   0.0    1.6  1  Methyltransf_2   O-methyltransferase domain
  ------ inclusion threshold ------
      0.011   15.6   0.0      0.033   14.0   0.0    1.9  2  Methyltransf_31  Methyltransferase domain
       0.02   15.6   0.1       0.11   13.2   0.0    2.3  2  Methyltransf_25  Methyltransferase domain
      0.044   13.5   0.0       0.17   11.6   0.0    1.8  2  Ad_Cy_reg        Adenylate cyclase regulatory domain


Domain annotation for each model (and alignments):
>> Methyltransf_2  O-methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.9   0.0   7.6e-19   3.4e-15      15     207 ..     198     423 ..     180     426 .. 0.77

  Alignments for each domain:
  == domain 1  score: 55.9 bits;  conditional E-value: 7.6e-19
                     ..HHHHHS--..HHHHHTSSHHHHHHHHHHHH...TTHHHHHHHHHHSS-GGG-..SEEEEET-TTSHHHHHHHHH-TT-EEEEEE-HH.HHHHH CS
  Methyltransf_2  15 iifkkafGis..lfeaikrdeeerakfnkglq...essslvakkvleafdlegl..kslvDvGGGtGalakaivsayPtikvivfDlpe.VveaA 101
                       f+ a+ ++  lf+  ++d++ +ak+   l+   ++    ++++++a+d + l   ++vD GG +G +  a +   P+ k iv D++   +e  
      EEA19395.1 198 AAFNVAYRTEddLFQHFHKDADLNAKYHGYLAgrvNTPLWSVDRLITAWDWSALgdATVVDCGGSSGHTCVALAPICPQTKFIVQDMSAdAMELG 292
                     5678888777789999999*99999987666511155667899*******998844589***************************975144444 PP

                     HH...HS--........---TTEEEEES-TTTS-----SEEEEESSGGGS-HHHHHHHHHHHHHH--........TT-EEEEEE----...TTS- CS
  Methyltransf_2 102 ke...hlsa........geeervefvgGdffkdslPeaDaillkrvlhDwsdekcvklLkrvkkalp........agGkvivveavlg...adps 174
                     +e   +ls+        ++++r++f   +ff ++   aD++++ ++lhDw+d + vk++k +  al          + +v++ e +++   ++++
      EEA19395.1 293 REnvaFLSSsdssspyhDLTSRITFATHNFFTEQKTLADVYIFRHILHDWDDRNSVKIIKSLVPALEkksaqnngRHPRVLISEGIVPpspEKRR 387
                     4311133321111111145689****************************************99998788874444447*******861114555 PP

                     --HHHHHH...HHHHHHCSS-----HHHHHHHHHHC CS
  Methyltransf_2 175 geletelv...dlimlvqteGkeRteaeyeellsea 207
                     g+++++++   d iml+ ++ +eR+ +++ +++++a
      EEA19395.1 388 GTVTEKMIrieDSIMLAAHNARERNVQDFIAIFQTA 423
                     66677777999999****************999876 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0      0.93   4.2e+03      85     113 ..     118     146 ..      68     185 .. 0.53
   2 ?   14.0   0.0   7.4e-06     0.033       4      49 ..     253     297 ..     251     362 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.93
  Methyltransf_31  85 naladpdkileeiervlkpggilliedpr 113
                      +a+  p + l ++ r+  ++gi+  ++p 
       EEA19395.1 118 AATGLPLDELTRAVRYAITNGIFTENTPG 146
                      33333333333555555556665555555 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 7.4e-06
  Methyltransf_31   4 glrvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielArenaq 49 
                      + +v+D+G  +G+ + +la  ++p+ +++  D+s++a el ren +
       EEA19395.1 253 DATVVDCGGSSGHTCVALA-PICPQTKFIVQDMSADAMELGRENVA 297
                      5689***************.99********************9765 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.1      0.73   3.3e+03      22      43 ..     162     183 ..     146     220 .. 0.62
   2 ?   13.2   0.0   2.4e-05      0.11       1      44 [.     256     305 ..     256     361 .. 0.63

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.73
                      SEEEEEESSHHHHHHHHHHHHH CS
  Methyltransf_25  22 akvtgvDiseemleaareraee 43 
                      +    +D++ ++l+a++ +++e
       EEA19395.1 162 HLRDICDFNTDFLAAIQIKLAE 183
                      5556788888888888877643 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 2.4e-05
                      EEEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHH......T CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlgkakvtgvDiseemleaareraee......e 44 
                      v+d+G  +G+++ ala  +++ k++  D+s++++e  re+++       +
       EEA19395.1 256 VVDCGGSSGHTCVALAPICPQTKFIVQDMSADAMELGRENVAFlsssdsS 305
                      89*****************99*****************999654333321 PP

>> Ad_Cy_reg  Adenylate cyclase regulatory domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0       0.4   1.8e+03      64      86 ..      10      32 ..       7      58 .. 0.82
   2 ?   11.6   0.0   3.8e-05      0.17      55     160 ..     107     215 ..     101     229 .. 0.77

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.4
   Ad_Cy_reg 64 isektGidlellqrlqrAvGLpr 86
                +s ++G+++  l  l + +GLp 
  EEA19395.1 10 LSSTVGLKVTELSNLLKTAGLPE 32
                678999**************996 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 3.8e-05
   Ad_Cy_reg  55 dgtyvsareisektGidlellqrlqr.Av..GLprvddpDaavllraDaeaaarakrfldlGldedqivavarv.LaegLsraaevlReaalkallepg 149
                  g+ +sa+++s++tG++l+ l r  r A+  G+ + ++  + + + a   a ar k+++d+   + + +a++++ Lae L+  a  + +a  +a+  + 
  EEA19395.1 107 SGSSISAEDLSAATGLPLDELTRAVRyAItnGIFT-ENTPGLFAHSAASAALARNKHLRDICDFNTDFLAAIQIkLAEALKARASGASDAPHAAFNVAY 204
                 57889****************99877465446544.666677777777778889999999986666666555554******999999999999988888 PP

   Ad_Cy_reg 150 aselelakaae 160
                 ++e +l ++ +
  EEA19395.1 205 RTEDDLFQHFH 215
                 88888877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (450 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       411  (0.0229238); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 3028.16
//
Query:       EEA19396.1  [L=420]
Description: salicylate hydroxylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.2e-25   89.6   0.0    1.3e-11   44.3   0.0    2.1  2  FAD_binding_3   FAD binding domain
    1.5e-06   28.3   0.6    4.8e-06   26.7   0.6    1.9  1  NAD_binding_8   NAD(P)-binding Rossmann-like domain
      2e-06   27.7   2.4    0.00013   21.6   1.3    2.1  2  DAO             FAD dependent oxidoreductase
    2.4e-06   26.9   2.2    3.7e-06   26.3   2.2    1.3  1  FAD_binding_2   FAD binding domain
    9.2e-06   25.1   1.3      0.002   17.4   0.7    2.1  2  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
     0.0001   21.1   1.1    0.00024   19.9   1.1    1.6  2  HI0933_like     HI0933-like protein
    0.00067   19.1   0.3      0.001   18.5   0.3    1.2  1  FAD_oxidored    FAD dependent oxidoreductase
    0.00074   18.7   0.3     0.0018   17.4   0.3    1.5  1  Lycopene_cycl   Lycopene cyclase protein
     0.0026   17.1   0.2     0.0053   16.1   0.2    1.5  1  AlaDh_PNT_C     Alanine dehydrogenase/PNT, C-terminal domain
     0.0033   16.6   1.2     0.0047   16.1   1.2    1.2  1  GIDA            Glucose inhibited division protein A
     0.0034   16.6   0.5     0.0058   15.9   0.5    1.3  1  Thi4            Thi4 family
     0.0038   16.2   0.4       0.11   11.3   0.3    2.2  2  Trp_halogenase  Tryptophan halogenase
     0.0071   16.3   0.2       0.28   11.2   0.2    2.3  2  NAD_binding_9   FAD-NAD(P)-binding
  ------ inclusion threshold ------
       0.01   15.1   0.5      0.017   14.4   0.5    1.3  1  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
      0.018   14.1   0.0       0.17   10.9   0.0    2.1  2  SE              Squalene epoxidase
      0.019   14.3   0.1      0.054   12.8   0.0    1.7  2  Amino_oxidase   Flavin containing amine oxidoreductase
      0.076   13.6   1.3       0.17   12.5   1.3    1.6  1  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
       0.11   12.4   0.1       0.18   11.7   0.1    1.3  1  3HCDH_N         3-hydroxyacyl-CoA dehydrogenase, NAD binding 
       0.17   11.5   0.1       0.37   10.4   0.1    1.6  1  ApbA            Ketopantoate reductase PanE/ApbA
       0.34    9.7   0.5       0.49    9.1   0.5    1.1  1  MCRA            MCRA family


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.3   0.0   1.5e-14   1.3e-11       3     172 ..       4     168 ..       2     240 .. 0.74
   2 !   43.5   0.0   2.7e-14   2.4e-11     280     345 ..     295     360 ..     267     364 .. 0.95

  Alignments for each domain:
  == domain 1  score: 44.3 bits;  conditional E-value: 1.5e-14
                    EEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSSS--EEEHHHHHHHHHTT-H.HHHHHHSEECCCCEEEEEEE...CCCCCEEEEEHHCHH CS
  FAD_binding_3   3 dVlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlpradglnqrtmellrqlGle.drilaegapnelmgealyne...lsdtpkaradleles 94 
                    +V+IVGaG aGl++a  L+eaG +v++ ek + +++ + a +l++  +++l + G   dr++a+    +l +++ +++   l+++ +++a+ +  +
     EEA19396.1   4 EVIIVGAGIAGLTAAVSLCEAGHSVRIFEKSKFAAEIGAAVVLSPNAVRVLSTFGFScDRAQARQ--LQLWETVDGTTlnlLGKVDHREAEQKYGA 97 
                    8******************************************************9723333333..34333333333333455544444444446 PP

                    CST-CEE--HHHHHHHHHHHHHHHTEEETCSEEEECCEECCCCCCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHHH CS
  FAD_binding_3  95 spervtvypqteleriLvehaeerglqvrfktevesleqdeegvtaevrdketgeeetvrakYlvGaDGgrStvrktl 172
                       +++ +  ++ + +L+++ ++++++++   +v+    d + ++  ++ ++ g++    a+ +v+aDG rS  rk++
     EEA19396.1  98 PLYAIHRVDLHNELLLLISQESKKPATIYLRSKVV----DADPEKGMIQLED-GTK--HYADLIVAADGLRSVLRKAV 168
                    6777777777777778888889999******9999....7777777776664.444..48***************987 PP

  == domain 2  score: 43.5 bits;  conditional E-value: 2.7e-14
                    SSEETTEEE-GGGTEEE-STTSHHHHHHHHHHHHHHHHHHHHHTTSS-GGGGHHHHHHHHHHHHHH CS
  FAD_binding_3 280 kyrkgrvflaGDAaHihpPtgGqGlNtaiqDavnLawkLaavlkGeAkeelLdtYeeerravaqav 345
                    +++ grv l+GDAaH + P gGqG+N ai+D   L+  L  v + +  +++L  +e+ rr++a +v
     EEA19396.1 295 RWSYGRVVLIGDAAHPMLPFGGQGSNQAIEDGGALGYLLRDVDNHSDIPDRLALFEQVRRKRASRV 360
                    89******************************************9999************999876 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.7   0.6   5.4e-09   4.8e-06       1      28 [.       7      34 ..       7      41 .. 0.96

  Alignments for each domain:
  == domain 1  score: 26.7 bits;  conditional E-value: 5.4e-09
                   EE--SHHHHHHHHHHHCCTEEEEEE-SS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekr 28
                   IvGaG++Gl+aA  L +ag++v ++ek+
     EEA19396.1  7 IVGAGIAGLTAAVSLCEAGHSVRIFEKS 34
                   9*************************96 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.6   1.3   1.5e-07   0.00013       2      34 ..       5      39 ..       4      48 .. 0.89
   2 ?    4.7   0.0     0.022        20     159     299 ..     121     272 ..     108     303 .. 0.56

  Alignments for each domain:
  == domain 1  score: 21.6 bits;  conditional E-value: 1.5e-07
                EEEECTSHHHHHHHHHHHHTT..EEEEESSSSTTS CS
         DAO  2 vviiGGGiiGlstAyeLarrg..Vtllekgdiags 34
                v+i+G+Gi+Gl++A  L ++g  V ++ek+++a++
  EEA19396.1  5 VIIVGAGIAGLTAAVSLCEAGhsVRIFEKSKFAAE 39
                9****************999999*******87774 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.022
                 TT-EEEESECEEEEEEEETCEEEEEEECTEEEEEEEEEEE--GGGHHHH.HTT.CTTT...SEEEEEEEEEEEEEECCTHSTGSGCSEEEEEEEETTTT CS
         DAO 159 lGveilegtevtgleeedgkvwgverttpgendaadavVnaaGawsdll.gll.keld...lpispvrgqvlvlkplseklvspaailpvpetdddgrg 252
                 + ++i+++++v++  +++++  ++   ++g+++ ad +V a G+ s  l + + +  d   +p +++ +  + + p++e l+s+  ++ +++      g
  EEA19396.1 121 KPATIYLRSKVVDA-DPEKGMIQL---EDGTKHYADLIVAADGLRS-VLrKAVfRGEDvnaKP-TGLSAFRFLI-PTPE-LESHSSLADLRQ--WKQPG 209
                 4589*********9.454555555...3387766799******998.3434446444411133.5566666666.5555.333334444433..33344 PP

                 EEEEEE...............TTSEEEEEESSE.........EETTCSSTSCSHHHHHHHHHHHHHHSGGG CS
         DAO 253 vyvtpr...............kdgrvlvGgtad.........eesgdddpevdeedidellealrklfPql 299
                 v ++++               +        +++         ++  +++ +  e+  + +le+ +++ P+l
  EEA19396.1 210 VTIIADttdtvnerhmvwydcR--------SGEvqnlvgihpTRTIPGNGDNLEDIKASMLEEFAHFHPDL 272
                 5555543334332222222222........22233333333222333333344444555666666666665 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.3   2.2   4.1e-09   3.7e-06       2      52 ..       5      49 ..       4      55 .. 0.83

  Alignments for each domain:
  == domain 1  score: 26.3 bits;  conditional E-value: 4.1e-09
                   EEEE--SHHHHHHHHHHHHTTT-EEEEESSSGGGSGGGG--S-EE-TT..S CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGlkvavvekeqefggatawsqGgidavlspe 52
                   vi++G+G+AGL+AA+++ eaG++v + ek +       +++ g+++vlsp+
     EEA19396.1  5 VIIVGAGIAGLTAAVSLCEAGHSVRIFEKSKF------AAEIGAAVVLSPN 49
                   9****************************985......5555555555555 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.7   2.3e-06     0.002       2      32 ..       4      33 ..       3      53 .. 0.86
   2 !    5.7   0.0    0.0084       7.5     200     239 ..     125     162 ..     117     180 .. 0.86

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 2.3e-06
                 SEEEE--SHHHHHHHHHHHHHTS-EEEEETT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  2 dvvviGgGpAGlaaaltlaqagakvtlvele 32
                 +v+++G+G+AGl+aa  l +ag+ v ++e +
   EEA19396.1  4 EVIIVGAGIAGLTAAVSLCEAGHSVRIFE-K 33
                 59*************************95.3 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.0084
                  EEESCEEEEEEETTEEEEEEETTSCEEEESEEEE-S-EEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 200 vklgtsvkeidgngeklevvledgeeidadlvvvavGvrp 239
                  ++l+++v+++d+++     +ledg++  adl+v a G+r 
   EEA19396.1 125 IYLRSKVVDADPEKG--MIQLEDGTKHYADLIVAADGLRS 162
                  788999999999988..7899****************986 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   1.1   2.7e-07   0.00024       2      33 ..       4      35 ..       3      43 .. 0.92
   2 ?   -2.5   0.0       1.8   1.6e+03     117     165 ..     116     161 ..     111     163 .. 0.68

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 2.7e-07
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SSS CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVlllekak 33
                 +vi++G+G AGl aA+s+ ++g++V ++ek k
   EEA19396.1  4 EVIIVGAGIAGLTAAVSLCEAGHSVRIFEKSK 35
                 79***************************986 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 1.8
                  HHHHHHT-EEE-S--EEEEECETTE.EEEEE.TTEEEEESEEEE----S CS
  HI0933_like 117 kelkeagvklrletevksvekeedgkfrvktkseeeleadklvlAtGGl 165
                  ++ +++  +++l+++v +++ e+    +++++++++  ad +v A G  
   EEA19396.1 116 SQESKKPATIYLRSKVVDADPEK---GMIQLEDGTKHYADLIVAADGLR 161
                  55566777889999999884433...46888778888888777777655 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.3   1.2e-06     0.001       1      33 [.       4      36 ..       4      37 .. 0.94

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 1.2e-06
  FAD_oxidored  1 DvvVvGGgpaGvaAAiaAaraGakvlLveergv 33
                  +v++vG+g+aG++AA++ ++aG +v + e++++
    EEA19396.1  4 EVIIVGAGIAGLTAAVSLCEAGHSVRIFEKSKF 36
                  59**************************99876 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.3     2e-06    0.0018       2     143 ..       5     162 ..       4     174 .. 0.68

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 2e-06
  Lycopene_cycl   2 vvviGaGpAglslAarlteakpglkvv.....lieaspsllfpnny..vWsdefedlgaleecvehsWsg...tivylddgk.killg....raYg 82 
                    v+++GaG Agl  A  l ea   +++        e ++ ++ ++n   v s ++   ++ ++ + + W+    t++ l ++  +++ +     +  
     EEA19396.1   5 VIIVGAGIAGLTAAVSLCEAGHSVRIFekskfAAEIGAAVVLSPNAvrVLSTFGFSCDRAQARQLQLWETvdgTTLNLLGKVdHREAEqkygAPLY 100
                    9****************6666665553222223445556555555437899999999998888888886422244444332202222211124566 PP

  Lycopene_cycl  83 rvsskrlkeellerlv....engvklleakvesveeeeageslvvleggrkirarlvvdarglas 143
                     +++ +l++ell  +     + + ++l++kv  + +e+    ++ le+g k +a l+v a gl s
     EEA19396.1 101 AIHRVDLHNELLLLISqeskKPATIYLRSKVVDADPEKG---MIQLEDGTKHYADLIVAADGLRS 162
                    8********9986555311145689******88888888...********************765 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.2   5.9e-06    0.0053      29      62 ..       3      36 ..       1      71 [. 0.89

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 5.9e-06
                 -EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHH CS
  AlaDh_PNT_C 29 akvlviGgGvaGlqAiatakglgakVtvlDvrpa 62
                  +v+++G+G+aGl A+    + g +V+++++++ 
   EEA19396.1  3 LEVIIVGAGIAGLTAAVSLCEAGHSVRIFEKSKF 36
                 579**************************99865 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   1.2   5.3e-06    0.0047       1      29 [.       4      32 ..       4      56 .. 0.84

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 5.3e-06
                CEEEE-SSHHHHHHHHHHHHTT--EEEEE CS
        GIDA  1 dviViGgGhAGceAAlaaarlGakvlLit 29
                +vi++G+G AG+ AA+ + ++G++v ++ 
  EEA19396.1  4 EVIIVGAGIAGLTAAVSLCEAGHSVRIFE 32
                59************************993 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.5   6.5e-06    0.0058      19      50 ..       4      34 ..       1      45 [. 0.90

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 6.5e-06
                EEEEE--SHHHHHHHHHHHHCTTS-EEEEESS CS
        Thi4 19 DvvivGaGssGLtaayylakkpdlkvailers 50
                +v+ivGaG +GLtaa  l ++ +  v i+e+s
  EEA19396.1  4 EVIIVGAGIAGLTAAVSLCEA-GHSVRIFEKS 34
                79******************9.9999999986 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.3   0.3   0.00013      0.11       2      46 ..       5      45 ..       4      66 .. 0.81
   2 ?    2.7   0.0     0.051        46     189     220 ..     140     171 ..     110     178 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00013
                    EEEE--SHHHHHHHHHHHHHTTTSSEEEEEE-SSS---SS-EE-- CS
  Trp_halogenase  2 ivivGGGtaGwlaAaalakalkgklevtlveseeigtvgvGeati 46
                    ++ivG+G+aG +aA  l +a+   ++v + e++++   ++G a +
      EEA19396.1  5 VIIVGAGIAGLTAAVSLCEAG---HSVRIFEKSKFA-AEIGAAVV 45
                    99******************9...889999998875.46666655 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.051
                     EEEETTS-EEE-SEEEE-SGGG-IIIIIIT-- CS
  Trp_halogenase 189 slrledgreveadlfiDcsGfrgllieqaLkt 220
                      ++ledg++  adl++ + G r+ l + ++++
      EEA19396.1 140 MIQLEDGTKHYADLIVAADGLRSVLRKAVFRG 171
                     5789********************99988765 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.2   0.00031      0.28       2      37 ..       7      37 ..       6      53 .. 0.86
   2 ?    2.8   0.0      0.11     1e+02     119     154 ..     126     159 ..     107     161 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00031
  NAD_binding_9  2 ivGaGprGlavlerLlarakkkspleitlfdpsepg 37
                   ivGaG++Gl+++  L++       +++ +f++s++ 
     EEA19396.1  7 IVGAGIAGLTAAVSLCEA-----GHSVRIFEKSKFA 37
                   9***************99.....4888889988774 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.11
  NAD_binding_9 119 vhraevvdleeradgqavlladgaslaadaVvLAlG 154
                    ++r++vvd +++++  ++ l+dg+++ ad +v A G
     EEA19396.1 126 YLRSKVVDADPEKG--MIQLEDGTKHYADLIVAADG 159
                    46888888887755..6899************9977 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.5   1.9e-05     0.017       1      34 [.       6      38 ..       6      56 .. 0.91

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.9e-05
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEkgnign 34
                 iI+GaG aGl+aa+ l +ag  ++ i Ek +  +
   EEA19396.1  6 IIVGAGIAGLTAAVSLCEAGH-SVRIFEKSKFAA 38
                 8*******************9.7******98665 PP

>> SE  Squalene epoxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0       0.2   1.8e+02       2      21 ..     151     170 ..     150     194 .. 0.77
   2 ?   10.9   0.0   0.00019      0.17     132     200 ..     301     366 ..     221     379 .. 0.91

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.2
          SE   2 AkltvvcDGifsklRkelsd 21 
                 A l v +DG+ s lRk++  
  EEA19396.1 151 ADLIVAADGLRSVLRKAVFR 170
                 8999************9874 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00019
          SE 132 lillGDalnmRHPltggGmtvalnDivllskllkpledlsdeekvleelksfyvkRkeldavvnvLsia 200
                 ++l+GDa     P  g G   a++D   l  ll+++   ++++ + ++l  f   R++ ++ v +Ls+a
  EEA19396.1 301 VVLIGDAAHPMLPFGGQGSNQAIEDGGALGYLLRDV---DNHSDIPDRLALFEQVRRKRASRVQILSKA 366
                 789*****9999*********************988...78888***********************98 PP

>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   6.1e-05     0.054       1      23 [.      12      34 ..      12      37 .. 0.94
   2 ?   -1.7   0.0       1.4   1.3e+03     219     259 ..     119     157 ..      70     167 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 6.1e-05
                   HHHHHHHHHHHHTTEEEEEEESS CS
  Amino_oxidase  1 laGLaaArqLlsaGfdVtvlEar 23
                   +aGL+aA  L +aG++V ++E +
     EEA19396.1 12 IAGLTAAVSLCEAGHSVRIFEKS 34
                   8********************87 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 1.4
                    TTTTEEEETSEEEEEEEEETTCEEEEETTSTEEEESEEEE- CS
  Amino_oxidase 219 elrgldirlntrVkeikregdgvtvtledgevveaDaVvvT 259
                    ++++ +i l+++V + +   ++  ++ledg++  aD +v +
     EEA19396.1 119 SKKPATIYLRSKVVDADP--EKGMIQLEDGTKHYADLIVAA 157
                    577788888888865555..666666689999888887655 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   1.3   0.00019      0.17       2      31 ..       5      34 ..       4      44 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00019
                EEEECSSHHHHHHHHHHHHTTSEEEEEESS CS
   Pyr_redox  2 vvvvGgGyiglElAgalaelgkkVtvvers 31
                v++vG+G  gl +A  l e g++V ++e s
  EEA19396.1  5 VIIVGAGIAGLTAAVSLCEAGHSVRIFEKS 34
                89*************************987 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.1    0.0002      0.18       2      40 ..       5      43 ..       4      67 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.0002
                EEEE--SCCHHHHHHHHHHTT-EEEEE-S-HHHHHHHHH CS
     3HCDH_N  2 vaviGaGtmGagiaavfasagleVvlvdiseealekale 40
                v ++GaG+ G   a  +++ag++V++++ s+ a+e +++
  EEA19396.1  5 VIIVGAGIAGLTAAVSLCEAGHSVRIFEKSKFAAEIGAA 43
                789*************************99988887665 PP

>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.1   0.00041      0.37       1      31 [.       5      35 ..       5      63 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00041
                EEEES-SHHHHHHHHHHHHHTHCEEEE-SCH CS
        ApbA  1 iailGaGaiGsllaakLakagadvtlilrsr 31
                + i+GaG  G + a++L +ag+ v +  +s+
  EEA19396.1  5 VIIVGAGIAGLTAAVSLCEAGHSVRIFEKSK 35
                57**********************9988877 PP

>> MCRA  MCRA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.5   0.00055      0.49       4      39 ..       5      36 ..       3      45 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00055
                EEEE--SHHHHHHHHHHHHTT---GGGEEEE-SS-- CS
        MCRA  4 aylvGsGiasLaaAvyLirdakvpgenihileelkv 39
                + +vG+Gia+L+aAv L + +    + + i+e++k 
  EEA19396.1  5 VIIVGAGIAGLTAAVSLCEAG----HSVRIFEKSKF 36
                78***************9875....46777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (420 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       455  (0.0253779); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              20  [number of targets reported over threshold]
# CPU time: 0.58u 0.26s 00:00:00.84 Elapsed: 00:00:00.43
# Mc/sec: 2944.62
//
Query:       EEA19397.1  [L=2134]
Description: polyketide synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      1e-74  251.3   0.0    1.9e-74  250.4   0.0    1.5  1  ketoacyl-synt    Beta-ketoacyl synthase, N-terminal domain
    9.1e-59  199.1   0.2    9.1e-59  199.1   0.2    2.1  3  SAT              Starter unit:ACP transacylase in aflatoxin b
    3.7e-39  135.1   0.0      8e-39  134.0   0.0    1.5  1  Acyl_transf_1    Acyl transferase domain
    1.4e-35  121.9   0.0    3.7e-35  120.5   0.0    1.8  1  Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
    1.1e-25   91.1   0.0    3.4e-25   89.5   0.0    1.9  1  Thioesterase     Thioesterase domain
    5.5e-19   68.3   8.2    1.2e-10   41.6   1.8    2.9  2  PP-binding       Phosphopantetheine attachment site
    1.1e-07   31.4   0.0    2.1e-07   30.5   0.0    1.4  1  PS-DH            Polyketide synthase dehydratase
      5e-05   24.0   0.1     0.0067   17.0   0.0    2.8  3  Abhydrolase_6    Alpha/beta hydrolase family
    0.00011   22.6   0.0    0.00036   21.0   0.0    2.0  1  KAsynt_C_assoc   Ketoacyl-synthetase C-terminal extension
    0.00067   19.1   0.2     0.0014   18.0   0.2    1.4  1  Thiolase_N       Thiolase, N-terminal domain
  ------ inclusion threshold ------
      0.047   13.3   0.1       0.12   11.9   0.0    1.7  2  Abhydrolase_1    alpha/beta hydrolase fold


Domain annotation for each model (and alignments):
>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  250.4   0.0   1.2e-77   1.9e-74       2     253 .]     381     630 ..     380     630 .. 0.95

  Alignments for each domain:
  == domain 1  score: 250.4 bits;  conditional E-value: 1.2e-77
                    --EEEEEEEEEBTTBSSHHHHHHHHHTT---EEES-TTSSCGTTSBTSSTTEEE-BSS.EEE..S.TTEGGTTSTHHHHHHHCTS-HHHHHHHHHH CS
  ketoacyl-synt   2 epvaivGmgarfPggndveefwelLlegrdaiselpadrwdadklydpparaagkiktklggfld.vddfdpeffgispreaeamdpqqrllleaa 96 
                    ep+ai+Gm++rfP++++++e+w+lL +g d+ + +padr++a+ +  ++++  +k+k+++g+f++    fdp+ff++sp+ea+++dpqqrl+l++a
     EEA19397.1 381 EPIAIIGMSGRFPNSTNTDELWKLLEQGIDCHKVIPADRFNASLYVSQDRNSRNKSKSPYGCFIEkPGMFDPRFFNMSPKEAAQTDPQQRLALVTA 476
                    89********************************************************************************************** PP

                    HHHHHHHTS-HHTCTTGG...EEEEEEESSTHHHHHHHHHHHTTGGGSCTTHHHHHSTTHHHHHHHHHHT--SSEEEEESGGGHHHHHHHHHHHHH CS
  ketoacyl-synt  97 wealedagltpeeldgsr...vgvfiGvgagdyaalaaldedgsevkaspkavgavlanviagrisyalglrGpsvtvdtACsSslvavhaavqsl 189
                    +eale ag+ p+ + +++   +g f G +  dy++l++++    + +++   v++v++++ +gr+s + +l Gpsv+vdtACsSs++a++ a+ s+
     EEA19397.1 477 YEALEMAGYVPNGTPSTQldrIGTFYGQTTDDYKDLNTSQ----DIDTYY--VSSVIRAFGPGRVSRSNQLGGPSVSVDTACSSSAMALNIACTSI 566
                    ***********9886666667**********998755444....355666..6777**************************************** PP

                    HTTS-SEEEEEEEE---SHHHHHHHHHTTBB-TTSGGGTTBTTB-SB-BB-EEEEEEEEECHHH CS
  ketoacyl-synt 190 rsgeadvalaGGvellltpeavagfsaagllspdgrckafdpkadGfvlGEGvGavvLkrleda 253
                    +s+e+d+a++GG+ ll +pe +ag+s+ +++s++g+ck+fd++adG+++GE v+ +v+krl+ a
     EEA19397.1 567 WSQECDTAVVGGMLLLGSPEMYAGLSKGHFISETGPCKTFDDSADGYCRGESVASIVIKRLDAA 630
                    ************************************************************9865 PP

>> SAT  Starter unit:ACP transacylase in aflatoxin biosynthesis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  199.1   0.2   5.6e-62   9.1e-59       2     240 .]       9     250 ..       8     250 .. 0.93
   2 ?   -3.6   0.0       4.4   7.2e+03     105     128 ..     996    1019 ..     979    1023 .. 0.85
   3 ?   -3.2   0.0       3.5   5.7e+03      15      78 ..    1032    1103 ..    1028    1106 .. 0.51

  Alignments for each domain:
  == domain 1  score: 199.1 bits;  conditional E-value: 5.6e-62
         SAT   2 lFGDqtadvlpeLrkLl.qakenplLrsFLekasealraeisrlpaaerkslprftslqellerysesglkspalssallciaqlaqfivyleenp.ee 98 
                 +FGD +  ++p L++Ll  ++e ++L++FL++a+ al+ae+ +l+  erkslp+ t+l  l e+ +++g+ +p+l  all+i+ql+qfi+++ee+p ++
  EEA19397.1   9 FFGDLSLPIHPALSQLLrAQTEYSILSRFLTQAKTALQAEATNLSVVERKSLPSLTDLYTLSETENSHGSDHPILAPALLVILQLGQFISWHEEHPeKR 107
                 7****************9999***********************************************************************6666157 PP

         SAT  99 ypspestylvGlCtGllaAaavacskslseLvplaveavrvafrlGlevarvaarleegsssssesWslavtglseeelekalaefneekglppasrvy 197
                 yp+++st+ +G+C G+++A+a++ +ksl+eL+plav+avr+afrlG ++++++++le    s +e+W+++ ++ +    e++l+++ +e+g+   +++y
  EEA19397.1 108 YPESDSTIFAGICVGQISATAISLAKSLTELLPLAVDAVRIAFRLGRLTTEARNDLE---LSLEETWAIVTPRDTSIPTEDVLDRIIKESGILGRRKPY 203
                 88899****************************************************...566688********************************* PP

         SAT 198 isavssssvtisGpPstl...eallksskakkkkkks.klpiyapyH 240
                  +a+ +++vti GpPstl   ++ l++ + ++++    +lpiyapyH
  EEA19397.1 204 ATAYFPKTVTIQGPPSTLrlvSDSLQKARGSSHTYFAsELPIYAPYH 250
                 ******************666566666666666666579******** PP

  == domain 2  score: -3.6 bits;  conditional E-value: 4.4
         SAT  105 tylvGlCtGllaAaavacskslse 128 
                    ++G++ G  aA  v+   s+s+
  EEA19397.1  996 NFVIGHSLGEYAALNVSGVLSISD 1019
                  589**********99998877776 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 3.5
         SAT   15 rkLlqakenplLr..sFLekasealraeisrlpaaerkslp......rftslqellerysesglkspalssa 78  
                  ++L+ ++++++L+  + L+++++a  ++++rl+ a  +          f+++qel +  +++g k+ +l+ +
  EEA19397.1 1032 ETLCTKNTHSMLAihATLDAVKSAAENKLGRLELACVNGPEdivlsgLFKDIQELSQHLKQQGFKCTVLQVP 1103
                  555544444444434555555555555555553322221112223335777777777777777777777665 PP

>> Acyl_transf_1  Acyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  134.0   0.0   4.9e-42     8e-39       2     280 ..     912    1201 ..     911    1230 .. 0.88

  Alignments for each domain:
  == domain 1  score: 134.0 bits;  conditional E-value: 4.9e-42
                     EEE--TT---TTTTCCHHHC-HHHHHHHHHHHHHCCHHHT--HHHHHHS--TTGGGSH..HHHHHHHHHHHHHHHHHHHHTT-TTSEEEE-TTH CS
  Acyl_transf_1    2 fvfsGqGsQwaGMGmeLlktskafaaviaradeafksqygfsvldvlrnnpeglldai..qfvqpaLaavqialaellkskGvrpaavvGHSlG 93  
                     f f+GqGs     G +L++ts  f+a ++r d+  +  y f+    +++    ++++    ++q+aL+ vqiala l+ s G +p  v+GHSlG
     EEA19397.1  912 FAFTGQGSVYLSLGQQLFETSSQFRADMRRFDQICQG-YEFKTFLPVIDGSATNFNDLspTQAQLALVSVQIALARLWASWGITPNFVIGHSLG 1004
                     89*******************************9999.99997666666666666655223689****************************** PP

                     HHHHHHHCCSSSHHHHHHHHHHHHHHHHHHT..S-EECCEECS...HHHHHHH...TT.EEEEEEECCCCECCEEHHHHHHHHHHHHHCC.CCE CS
  Acyl_transf_1   94 ElAaavvagalsseeallavvlrsrlmmqla..gpgdmaavel..aeeeeklr.cqddvvgavansprrvvisgsqealrelvervskegvgal 182 
                     E+Aa+ v g ls  + l  v +r      l       m+a+    ++++ ++     ++ +a++n+p+ +v+sg    ++el ++++++g+   
     EEA19397.1 1005 EYAALNVSGVLSISDTLYLVGIRASFLETLCtkNTHSMLAIHAtlDAVKSAAEnKLGRLELACVNGPEDIVLSGLFKDIQELSQHLKQQGFKCT 1098
                     ********************9999988877633567788887766777777777999************************************* PP

                     EECCCEECTTCCCCCCCCHHHHHHHHCCCHHCHHTTBEHCCCHHHHHHC.HHHHHHHHHHHCHCCHCCHHTTS....SSECC-CCEECSSSSCC CS
  Acyl_transf_1  183 venvnvavhspqvdaiadalasaladiaprkpkvakisstsldessere.lsaeywvanlrspvrfaeavlsa....aetiplvfveispHsll 271 
                     v +v +a+hs q d+i d l +a ++++  kp+++  s++     +e   +   y ++  r+pv f+ a+++a    + +++ + +ei p ++ 
     EEA19397.1 1099 VLQVPFAFHSSQTDPILDSLEKAAQSVRFLKPEIPVVSTLLGAVVDEIDvFGPSYLRRHAREPVNFDGALRQAcfdgLTDAQTIWLEIGPEPIC 1192
                     ***************************************999999765505569******************9955556778889999999999 PP

                     HCCCCCCCH CS
  Acyl_transf_1  272 laalektlk 280 
                     la ++  l 
     EEA19397.1 1193 LAMVKSILG 1201
                     998887666 PP

>> Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  120.5   0.0   2.2e-38   3.7e-35       1     117 [.     638     758 ..     638     759 .. 0.98

  Alignments for each domain:
  == domain 1  score: 120.5 bits;  conditional E-value: 2.2e-38
                      SEEEEEEEEEE--STSSSTSTTHHHHHHHHHHHHHHHT--GGGEEEEE-SS-SSHHHHHHHHHHHHHHHGGGGG....SCTSEEE-THHHH-B- CS
  Ketoacyl-synt_C   1 yavikgsavnsdgahnsltapngeaqaraiekalaeagvdpedvdyveahgtgtplgDpiElealkkvfgekar....kqplavgSvKsniGHl 90 
                      +avi g+++n++++++s+t+p+g  q+ +++k+l++ag+dp d+dyve+hgtgt+lgD+iE+++++++f+  +     ++pl vg+vK+niGH+
       EEA19397.1 638 LAVILGAGTNYSAYAASITQPHGPTQEMLYRKVLNQAGLDPFDIDYVEMHGTGTQLGDAIEMSSVSNIFAPVSPrrpiERPLHVGTVKPNIGHG 731
                      69*********99*********************************************************9988899*99************** PP

                      GGGHHHHHHHHHHHHHHHTEE--BTT- CS
  Ketoacyl-synt_C  91 eaAaGvaelikvvlalkhgvipptlnl 117
                      e+A+G+++lik++l+l+++ ipp++++
       EEA19397.1 732 ESASGITSLIKALLILREERIPPHIGI 758
                      ***********************9976 PP

>> Thioesterase  Thioesterase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.5   0.0   2.1e-28   3.4e-25       3     228 ..    1882    2119 ..    1880    2122 .. 0.77

  Alignments for each domain:
  == domain 1  score: 89.5 bits;  conditional E-value: 2.1e-28
                    EEEE--TTCCSGGGHHHHHHCTTCEEEEEEECSTTSTSHHHCTTCHHHHHHHHHHHHHHH-SSSSEEEEEETHHHHHHHHHHHHHHHCT-SEEEE CS
  Thioesterase    3 LflfppagGsasvfrslasklsdpvvevlavqlpgrerdepplesieelaaeyaealrqiqpegPyalfGhSlGgllAfevArqLesqGlavksl 97  
                    Lflfp++ Gsa++++ l++ ++d   +v+++  p  ++ ++  +siee+a  +++a+r+iq +gPy+l+G+S+Gg+ Afe+ArqL + G+ v  l
    EEA19397.1 1882 LFLFPDGSGSAAAYAALQEISPD--LVVYGLNSPFLKSADKYTCSIEEIATIMVQAVRSIQSHGPYTLAGWSAGGMYAFEAARQLIQAGELVSKL 1974
                    9****************999999..799*****99999********************************************************* PP

                    EEESCCCCCCHHCHHCCCHTTHHTHHHHHCCTTHHHCCTTTHCCHHHHHHHHHHHHHHHHHTCCS-TTSCSE.........HHCEEEEEEGSS-C CS
  Thioesterase   98 flidssapseteaqeasrraedeefveeltdlggtepeelledeellsellpalradyraleqyslrpeaaq.........klratlfngsddkl 183 
                    +lids+ +s+   +e + ++ +e f+   t l+g   +++ ++      +++ +++  ral+ ys  +++a            +  l  +  + +
    EEA19397.1 1975 ILIDSPCRST---YEPMPANLLE-FIMSSTILKGF-TDKSAPNR-----IVDHFKSTIRALQIYSPTKLDASrapevfiiwA-KKGLSEDLGNNE 2058
                    *****99988...5555555555.77777777764.55555555.....778888888888888755555555557666641.222222222222 PP

                    .TCCCCCCCHCH.................CHCTCES.CEEEEEESSHCCHHHS.HHHHHHHHHHH CS
  Thioesterase  184 .kdldtlelaer.................weqktsg.evsvhvlegdhfylle.drleavleiie 228 
                     +++d+     r                 we+  +g ++sv  + g+hf ++  ++++++   i+
    EEA19397.1 2059 rGNVDWS----RgvanwlfhreanagplgWEKLLPGrPISVADVAGNHFSMVNkSNSKSLSLAIS 2119
                    0223332....144457888888899999999998835889999999999998888887766665 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.6   1.8   7.1e-14   1.2e-10       5      64 ..    1666    1725 ..    1665    1728 .. 0.95
   2 !   29.4   0.6   4.8e-10   7.8e-07       3      51 ..    1772    1820 ..    1770    1833 .. 0.92

  Alignments for each domain:
  == domain 1  score: 41.6 bits;  conditional E-value: 7.1e-14
  PP-binding    5 elvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaela 64  
                  e +a+ +gv + e+ +++++ ++GlDSl+a+++l++l+e +++++p++ + e++t+++l 
  EEA19397.1 1666 ETIAQEIGVTAAELVDSATFVEFGLDSLMALTILSKLRESLQLDLPSDIFQELTTIGDLR 1725
                  7899**********************************************99*****995 PP

  == domain 2  score: 29.4 bits;  conditional E-value: 4.8e-10
  PP-binding    3 lrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveipl 51  
                  + +++a+++gv++ee+ + +dl++lGlDSl++++++++++ee+ ++++l
  EEA19397.1 1772 VYSIMAKQIGVEVEELLAVDDLSSLGLDSLMSLSIQGSIQEELSLKLEL 1820
                  6789***********999*************************999876 PP

>> PS-DH  Polyketide synthase dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.5   0.0   1.3e-10   2.1e-07      16     277 ..    1311    1588 ..    1299    1606 .. 0.75

  Alignments for each domain:
  == domain 1  score: 30.5 bits;  conditional E-value: 1.3e-10
                  EEEEEEE-.S-SS.TTTSEEETTEEB--TTHHHHHHHHHHHHTS---........-EEEEEEEE----.B-..-SS.-EEEEEEEEE-TTS-E.... CS
       PS-DH   16 vvfrnrlr.laelpwLrDHrvdgkvvlPgagylemaleAarqltges.......kavelrdvsilkalvlp..ede.pvevqlslepeedgadrawv 101 
                  vvf+++l+ ++    ++ H+++g ++ P  ++  mal ++  + +++       ++  + d +i k++++     + p  +++s ++  ++    +v
  EEA19397.1 1311 VVFESNLSePKLNALIAGHSLNGLALCPSGVFADMALTVGDYIRQKHqaklpasSGSNIVDMQIVKPVTITvpRVDtPELLRISGTANLEKG-IVEV 1406
                  5777777767778889************************9999877788888889999999999998765114444555666666664444.5899 PP

                  EEEEEEE-SS-TT.EEEEEEEEEE-----......--B--HHHHHHHS-SEE....E-...HHHHHHHHHHHSEEE-GGG--EEEEEEE..TTEEEE CS
       PS-DH  102 efeifSregggeewtehatGtvrlaegaa......aaavdlealqarcaepaslrsvs...saefYerlaargleyGpsFqglralwrg..dgeala 187 
                  +f  +S ++g+++   +a+  ++++ ++       + a  ++++ ++ ++ ++ ++v+   ++++Y+ + ++ ++y p++ g++++  +  + ea+a
  EEA19397.1 1407 TFGTYSSKSGKTD--QNAKCIIEFGDTKLwlnhwsRSAYLIQKRIEDLERGVKNGDVDklfEKTIYRLF-SAVVDYDPRYHGMKEVMINsnELEAVA 1500
                  ******9999986..444444444443335554542333333333333333334444444499******.999************999855667777 PP

                  EE---GGGSSTTTT-SB-HHHHHHHHHHG..GG..----------EEEEEEEEEEE-S...-BTS--EEEEEE----SS-EEEEEEEE-SS- CS
       PS-DH  188 elrlpeelaggesayvlhPallDaalQllaaal..saeaekadaaylPvaierlrvyrpssaageelwvharleeegarsivadltlvdedG 277 
                   ++l e +++g  +++  P  lD + Ql +  +    + +  + +y+  ++++ ++  ++  ++++  vh++++ ++++ +v+++++++  +
  EEA19397.1 1501 LVKLYEGTDAG--DFFCSPLWLDNLAQLAGFIMngVNVVDPRKFVYISHGWGSYQLA-DDIDPTKPYHVHVKMHPAEKNVVVGEVSIFQ-GD 1588
                  77777777765..59************77777889556788999*************.68899************************96.33 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.0     0.051        83      41      77 ..     959    1008 ..     896    1180 .. 0.75
   2 ?   -3.8   0.0       9.9   1.6e+04      54      81 ..    1523    1556 ..    1507    1640 .. 0.74
   3 !   17.0   0.0   4.1e-06    0.0067      49     115 ..    1927    1996 ..    1869    2080 .. 0.68

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.051
                     GGCS--HHHC.........HHHHHHHCCTT....TTSEEEEEETCH..HH CS
  Abhydrolase_6   41 dpppldledl.........adlaalldelaa..gggpvvlvGHSlG..Ga 77  
                     d+++++++dl         + +  +l++l a  g  p +++GHSlG  +a
     EEA19397.1  959 DGSATNFNDLsptqaqlalVSVQIALARLWAswGITPNFVIGHSLGeyAA 1008
                     45556666633332121112223355555559999999********6643 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 9.9
                     HHHHCCTT........TTSEEEEEETCHHHHHHH CS
  Abhydrolase_6   54 aalldelaa......gggpvvlvGHSlGGalala 81  
                     +a+l+++++      +++++v + H +G +  + 
     EEA19397.1 1523 LAQLAGFIMngvnvvDPRKFVYISHGWGSYQLAD 1556
                     3444444446777778888888888888875444 PP

  == domain 3  score: 17.0 bits;  conditional E-value: 4.1e-06
                     HCHHH.HHHHCCTT..TTSEEEEEETCHHHHHHHHHHCC.......EE.EEES-..----TTTS----TTHHHH CS
  Abhydrolase_6   49 dladl.aalldelaagggpvvlvGHSlGGalalaaapla.....lvvg.vlldppptalpagllaaalelllal 115 
                     ++a++ +++++++  ++gp  l G+S GG++a +aa+++     lv++ +l+d+    ++ ++ +++++ll+  
     EEA19397.1 1927 EIATImVQAVRSIQ-SHGPYTLAGWSAGGMYAFEAARQLiqageLVSKlILIDS---PCRSTYEPMPANLLEFI 1996
                     23445555566664.67777**************888889999766669*****...55555533333333322 PP

>> KAsynt_C_assoc  Ketoacyl-synthetase C-terminal extension
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0   0.0   2.2e-07   0.00036      14     111 ..     776     879 ..     764     880 .. 0.78

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 2.2e-07
  KAsynt_C_assoc  14 kVvteptpwpggi.....vgvNsfGfGGsnvHviLksnkkekrkeeskeeslprLlvlsgrteeaveallekleehlldaellsllneilseeis 103
                     +++ e+  +p+         vN fG  G n+  iL++ +  +     + ++  +++ + ++t+ ++++++++l +hl++ +++sl +  +++  +
      EEA19397.1 776 HIPLETAAFPRSQfrkrrLMVNNFGAAGGNSAFILEEGPIYEGHGVLD-SRPDHVISVTAKTAFSLQKNISNLIAHLEQYPQVSLSDLSYTTTAR 869
                     55555555555555555599*******************777766666.67789*****************************997766666655 PP

  KAsynt_C_assoc 104 r..lpyRGya 111
                     r  +p R+ a
      EEA19397.1 870 RvqHPLRASA 879
                     5559999755 PP

>> Thiolase_N  Thiolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.2   8.8e-07    0.0014      77     113 ..     544     580 ..     513     594 .. 0.80

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 8.8e-07
                 EEEEEEHGGGHHHHHHHHHHHHHHTTSHSEEEEEEEE CS
  Thiolase_N  77 pavtvnkvcsSglkavalaaqsiaageadvvvagGvE 113
                 p+v v+ +csS+++a++ a+ si ++e+d +v+gG+ 
  EEA19397.1 544 PSVSVDTACSSSAMALNIACTSIWSQECDTAVVGGML 580
                 7899*******************************95 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   0.0       5.5     9e+03      67      83 ..     988    1004 ..     972    1004 .. 0.76
   2 ?   11.9   0.0   7.6e-05      0.12      32     113 ..    1907    1984 ..    1867    2018 .. 0.74

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 5.5
                     HHHCTTSSEEEEEETHH CS
  Abhydrolase_1   67 ldalgddkltlvGhSmG 83  
                      ++ g+ +  ++GhS+G
     EEA19397.1  988 WASWGITPNFVIGHSLG 1004
                     5666778888*****99 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 7.6e-05
                     EEEEEETTSTTSSSTTTGB.CHHSHHHHHHHHHHH.HHHCTTSSEEEEEETHHHHHHHHHHHHH...GGGEEEEEEESE...CSSCCHH CS
  Abhydrolase_1   32 villDlrGvgySspapacinddygtasvaddldri.ldalgddkltlvGhSmGGmialayaaey...perVkalvllga...idpaasl 113 
                     v++l+++   + ++  +      ++  +a ++ ++ +     ++ tl G+S GGm a+++a +     e V++l+l+++   +     +
     EEA19397.1 1907 VYGLNSPFLKSADKYTC------SIEEIATIMVQAvRSIQSHGPYTLAGWSAGGMYAFEAARQLiqaGELVSKLILIDSpcrS-----T 1984
                     44555555555555554......45567777775527777777777*********************************5442.....3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2134 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       519  (0.0289475); expected 358.6 (0.02)
Passed bias filter:                      501  (0.0279436); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 1.12u 0.28s 00:00:01.40 Elapsed: 00:00:00.46
# Mc/sec: 13856.59
//
Query:       EEA19398.1  [L=567]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.8e-28   97.6  53.0    6.8e-28   97.6  53.0    3.5  2  MFS_1     Major Facilitator Superfamily
    2.7e-09   36.4  13.6    2.7e-09   36.4  13.6    2.7  2  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.6  53.0   7.5e-32   6.8e-28       3     322 ..      67     440 ..      65     450 .. 0.81
   2 ?   -1.2   2.9     0.084   7.5e+02     122     153 ..     457     488 ..     445     560 .. 0.65

  Alignments for each domain:
  == domain 1  score: 97.6 bits;  conditional E-value: 7.5e-32
       MFS_1   3 laaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll.fasslwlllvlrvlqGlgag 100
                  ++fl++l+ +i++ +    + e +g ++  ++++ t++ lg+++ +lp+G+    f  ++v++++l++fa g++++    +++ +l+v+rv++G+g++
  EEA19398.1  67 STTFLYGLDNTIVADVQG-SVVERFG-QVEKLSWIGTGFPLGSVAVILPFGFAFGTFNNKWVYIMSLVIFATGSAICGgA-PNMDALIVGRVIAGAGGA 162
                 567788888887666666.8899999.9999******************************************5555523.7766************** PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllgglla.sslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 + + +++ li++ ++ +er+ ++g+ ++++++G+ilgp++gg++a ss+ Wr++fy++ +++ ++  +   +l+ +  +  ++++   +          
  EEA19398.1 163 GQYLGVLNLITRFTTMQERSHYMGMTGLTWGAGTILGPVIGGAFAdSSATWRWAFYLNLVIYGVFSPI--YFLWLPSIPVIPEKSFLSKivamdwvgit 259
                 *********************************************99999***************886..555555555555544444457789999** PP

       MFS_1 189 .................................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevl 238
                                                                      ++ ++p  +++lk++ l +++ia  ++++ f+++ ++lply+ +v 
  EEA19398.1 260 lnagiyltwvmaltfggatyawnseqeialwvvfgvlllgfllqqyfmvFTSINQRIFP--GHFLKRRTLVLCFIATNCAATSFFAIIYYLPLYFEFVN 356
                 *******************9999777666666666555555544444442222222222..3444444332477777777789999************* PP

       MFS_1 239 glsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllll.vlvliGfglgfvfpsll 322
                 g s  l +++ l  + + +++ ++ +g  +  +   +++++  ++l+++  gl++   +++++ +++  +vliG+g+g ++ ++ 
  EEA19398.1 357 GDS-SLKSAVRLLPVVCTFVFWCIASGTAMPYVEYYFPWYVVSGILIAVGGGLMYSVDINTSTSAIYgYSVLIGCGGGAIMQAAY 440
                 ***.677887777777777899*************************************7777777769999***5555544443 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.084
       MFS_1 122 aigllsagfslGailgpllggllasslgWrav 153
                 +ig+++++   G++   +++g++ +++ +r+v
  EEA19398.1 457 VIGFINVAQIGGIMHSLAISGAIFQNYAFRYV 488
                 67777777777777777777777777777765 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.4  13.6     3e-13   2.7e-09      48     187 ..      96     230 ..      60     239 .. 0.87
   2 ?   -4.6   6.2      0.81   7.3e+03      23     120 ..     343     436 ..     331     446 .. 0.78

  Alignments for each domain:
  == domain 1  score: 36.4 bits;  conditional E-value: 3e-13
                 HHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHH CS
    Sugar_tr  48 sglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqla 146
                 +++i   f +G+++  l +g++  +f +k++++++ v+f  g+++++ a+   ++ +livgRv++G g  +++  v  +i  +++ + R+  ++++ l 
  EEA19398.1  96 LSWIGTGFPLGSVAVILPFGFAFGTFNNKWVYIMSLVIFATGSAICGGAP---NMDALIVGRVIAGAGGAGQYLGVLNLITRFTTMQERSHYMGMTGLT 191
                 567777788999999999********************************...9********************************************* PP

                 HHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHH CS
    Sugar_tr 147 itfGilvaaifglglnktsnadgwrillglqlvpallllil 187
                 + +G +++ ++g +++++s+  +wr+ ++l+lv+  +++ +
  EEA19398.1 192 WGAGTILGPVIGGAFADSSA--TWRWAFYLNLVIYGVFSPI 230
                 ********************..9*******99876555433 PP

  == domain 2  score: -4.6 bits;  conditional E-value: 0.81
                 HHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHH CS
    Sugar_tr  23 ltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlas 120
                 + ++     f + + +ss + s+v++  +v+ f++ +i+++  + ++  +f   + ++++++l  +g+ l++  + ++s+ +++   vl+G g G++ 
  EEA19398.1 343 AIIYYLPLYFEFVNGDSSLK-SAVRLLPVVCTFVFWCIASGTAMPYVEYYF---PWYVVSGILIAVGGGLMYSVDINTSTSAIYGYSVLIGCGGGAIM 436
                 44444444455555555566.578899999999999999999999888888...78999999999999999999999999999999999999988876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (567 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       659  (0.0367561); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.46
# Mc/sec: 3725.32
//
Query:       EEA19399.1  [L=390]
Description: alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.7e-12   45.1   0.1    1.7e-11   44.2   0.1    1.5  1  ADH_zinc_N    Zinc-binding dehydrogenase
    9.8e-07   28.6   0.0      2e-06   27.6   0.0    1.6  1  ADH_N         Alcohol dehydrogenase GroES-like domain
  ------ inclusion threshold ------
      0.011   15.1   0.3      0.011   15.1   0.3    1.6  2  AlaDh_PNT_C   Alanine dehydrogenase/PNT, C-terminal domain
      0.047   14.7   0.0        0.1   13.6   0.0    1.5  1  ADH_zinc_N_2  Zinc-binding dehydrogenase
      0.068   12.6   0.6       0.11   11.9   0.6    1.3  1  adh_short     short chain dehydrogenase


Domain annotation for each model (and alignments):
>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.2   0.1   4.8e-15   1.7e-11       3     127 ..     205     343 ..     204     346 .. 0.80

  Alignments for each domain:
  == domain 1  score: 44.2 bits;  conditional E-value: 4.8e-15
                 HHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTESEEEET..............TTCHHHHHHHHHTT.TSSEEEEEESSC....SHHHHHHHHHCEEEE CS
  ADH_zinc_N   3 GlaavqlAkalGaeviavdsseeklelakklGadeviny..............keadlverikeltg.gegvdvvfecvG....sgatleaalkllkpg 82 
                 G+aav++A a+Ga+via+ ++ + le++++   d++ ++              ++ +++++ +++   g +vdv+f+ +       + l++ + ++++g
  EEA19399.1 205 GSAAVKVALAMGANVIAMGRNGKALEQLQS---DHLNTTggtgkgcrletvliTN-NIQAKTAAIASfGLPVDVYFDISPpsasESTHLRSGILSVRHG 299
                 99********************86666655...5555555555566666665555.55555555556699*******9984443445578899****** PP

                 EEEEECSCTSSEEEEEHHHHHHTT-EEEEE-SSCHHHHHHHHHHH CS
  ADH_zinc_N  83 GrlvvvGggkgeeefdlrnlllkeksilGsllgslreefkealdl 127
                 Gr+ ++Gg kg+ +++l++++  + +i+G +++  r+++ +++++
  EEA19399.1 300 GRVSLMGGIKGDVSVPLGHVMHANMTIKGKWMYE-RDDILRLIKM 343
                 **********************************.9998888776 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.6   0.0   5.6e-10     2e-06       2     107 ..      32     142 ..      31     144 .. 0.74

  Alignments for each domain:
  == domain 1  score: 27.6 bits;  conditional E-value: 5.6e-10
                 TEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS--TT-EEEE-SEEE-SS......SHHHHTT-GGG-TTBEETTTSS-SS CS
       ADH_N   2 gevlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkklkvGdrVvvepliscge......CaaCkegeenlCeeakllgvsldGg 94 
                 g ++ikv +ag+      i++g+++++ ++p i+G  ++G v+++g + ++l+ Gd V++++     +          ++g+++  +++   g  +d +
  EEA19399.1  32 GSAIIKVLCAGLLSYSRDIYNGTRKYTLPTPSIPGSGAIGRVVALGADATSLREGDLVLCDIYLRGRDdrdvgaLMGVHDGHSERAKRMVH-GEWRDST 129
                 6789********************************************************9988764433332122233333333333222.2225777 PP

                 SBSEEEECGGGEE CS
       ADH_N  95 faeyvvvpekklv 107
                 +aeyv +p ++++
  EEA19399.1 130 YAEYVKLPLENCF 142
                 7777777766665 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.1   0.3     3e-06     0.011      36      70 ..     201     237 ..     188     270 .. 0.84
   2 ?   -3.1   0.1       1.1   3.9e+03      12      25 ..     297     310 ..     293     326 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 3e-06
                  TSHHHHHHHHHHHHTT-EEEEEESSHHHHHHHHH..T CS
  AlaDh_PNT_C  36 gGvaGlqAiatakglgakVtvlDvrparleqles..l 70 
                   G+ G +A+++a ++ga+V ++  + ++leql+s  l
   EEA19399.1 201 TGMFGSAAVKVALAMGANVIAMGRNGKALEQLQSdhL 237
                  5999****************************99542 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 1.1
                  GCTSEEETTCEETC CS
  AlaDh_PNT_C  12 ffggkgtlaGgvpg 25 
                   +gg++ l+Gg++g
   EEA19399.1 297 RHGGRVSLMGGIKG 310
                  57899999999996 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.0   2.9e-05       0.1      20     132 ..     269     381 ..     253     381 .. 0.67

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 2.9e-05
                   TT-EEEEEES-H....HHHH.HHHHHHE..EEEEEEEE----.S-EEE-CHHHCTTT-EEEE--GGG...-.-HHHHHHHHHHHHHHH----EEEE. CS
  ADH_zinc_N_2  20 gegvDvvldtvg....gealleaslkvl..pggGrlvsiggpplsaallkpakkrkgrsvkyeflfsmkasaqadileelaalieeGklrpvvdrv. 109
                   g  vDv +d         ++l+    +l  ++gGr+  +gg      ++    +  ++++k +++      ++ d + +l ++ e+G+lr+  ++v 
    EEA19399.1 269 GLPVDVYFDISPpsasESTHLRSG--ILsvRHGGRVSLMGGIKGDVSVPLGHVMHANMTIKGKWMY-----ERDD-ILRLIKMAESGRLRVDGGSVk 357
                   456888888866665422222222..3334676777666652244444444445556666666666.....3777.99**************99877 PP

                   .EEGGGHHHHHHHHHSS--SSEEE CS
  ADH_zinc_N_2 110 .fpleeaaeAhrylesgrarGKiV 132
                    + le+  eA++  +  +  G++V
    EEA19399.1 358 kYALEQWEEAFEVAAREAGPGRLV 381
                   7**********9988888877776 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.6   3.1e-05      0.11       2      47 ..     194     239 ..     193     269 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 3.1e-05
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee 47 
                 +vl+  a++ +G a +k  +++Ga+v++++r+ ++le++ +   ++
  EEA19399.1 194 TVLIAPATGMFGSAAVKVALAMGANVIAMGRNGKALEQLQSDHLNT 239
                 7999999999**************************9998776554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (390 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2628.76
//
Query:       EEA19400.1  [L=415]
Description: purine nucleoside permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.8e-137  457.8   0.1   2.1e-137  457.6   0.1    1.0  1  NUP       Purine nucleoside permease (NUP)


Domain annotation for each model (and alignments):
>> NUP  Purine nucleoside permease (NUP)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  457.6   0.1  1.1e-141  2.1e-137       2     313 .]      38     359 ..      37     359 .. 0.99

  Alignments for each domain:
  == domain 1  score: 457.6 bits;  conditional E-value: 1.1e-141
         NUP   2 vkvvivsmFegEaqawlerlk....laenitvpglsplypevhcnadgsvcqlvtGegeinaaasimaLvlsprFdLtktYfliaGiaGvnPkaatiGs 96 
                 +kv+i+smF++Ea++w+  ++    la+ni++pglspl+p+vhc+++++vcq++tGe+einaa++i+aL++s++FdLt+tYf+++GiaG++P++at+Gs
  EEA19400.1  38 PKVFIISMFAPEAEVWW-GIPdfnlLAHNISIPGLSPLFPHVHCTHNHEVCQVITGESEINAATTISALAFSDEFDLTSTYFMVGGIAGISPEVATTGS 135
                 9****************.6666999************************************************************************** PP

         NUP  97 vafaryavqvdlqyeidarelpkdwstgylplgtkepneypkeiygtevfelneaLrdwAvelakkakLkdseeaaayrakY.......eyaaAqkpPs 188
                 v+faryavqv+lqye+dare+p++wstgy+++g+  p++yp +iygtevfe+n++L+++Av++a+k kL+ds++aa+yra+Y        y+a+++pPs
  EEA19400.1 136 VTFARYAVQVALQYELDAREIPANWSTGYFAQGSYGPDQYPGSIYGTEVFEVNDNLKSMAVAFARKGKLTDSAQAASYRANYlngdgasIYQAGAAPPS 234
                 ****************************************************************************************99********* PP

         NUP 189 vvkcdtltsdtywsGkllseaaenltkllTngtgtycttaqEdnatleallraakaglvDfsRvivlRtasnFdrpppgvsaleslleaeqggfeaale 287
                 vv+cd++tsd+y++Gkllsea++n+t+l+Tngtgtyc+taqEdnatle+llraa +++vDf+R+iv+Rtas+Fdrp+pg++ ++++l+a+q+gfe+al+
  EEA19400.1 235 VVECDVATSDVYYTGKLLSEAFANTTSLFTNGTGTYCSTAQEDNATLEVLLRAALHKRVDFARIIVMRTASDFDRPYPGEDPAYHILYANQDGFEIALQ 333
                 *************************************************************************************************** PP

         NUP 288 nlylaGsevveeivknWestykkgvk 313
                 n+y+aG++vv++i++ W++t+++gvk
  EEA19400.1 334 NIYNAGVHVVQGILDGWKHTFQHGVK 359
                 **********************9985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (415 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       479  (0.0267165); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2889.43
//
Query:       EEA19401.1  [L=354]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.5e-19   70.9   8.2    2.4e-17   63.7   8.2    2.2  1  Glyco_hydro_12  Glycosyl hydrolase family 12


Domain annotation for each model (and alignments):
>> Glyco_hydro_12  Glycosyl hydrolase family 12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.7   8.2   1.3e-21   2.4e-17       3     212 ..     105     351 ..     103     353 .. 0.74

  Alignments for each domain:
  == domain 1  score: 63.7 bits;  conditional E-value: 1.3e-21
                     EEEEE--TTEEEEEEEEEEEE-SSEE.EEEEEEEEEEESSG......B--EEEEE-BGGGTB--TT--..--EEGGGEEEEEEEEEEEE...... CS
  Glyco_hydro_12   3 ysvennlWgskegsgsvavkvdgeki.tssgasahtswkek......gypevygGeksvksysnsgva..lpvkvssvssiptevsfsi...... 82 
                     y+ + n Wg  +  g +a     +++ t+ +++ +t+   +      +yp   + +++v++y n +v   lp  +s+++s+  ++s+ +      
      EEA19401.1 105 YTYNPNQWGVINADGPNATSSMCMNVtTFLNETYPTKTSAPewfvtwSYPPGPE-NQPVHAYPNVEVSkgLPLTLSDLKSLNIDMSWTYalgnlp 198
                     8899999*9988777665544444431455555555555544556667776543.4568888776654338999*************86222222 PP

                     ...E-T......T--EEEEEEEEEESSTT-S..--TT-EEEEEEEE.EES.---SSEEEE...EEEETTEEEEEEE......EESSSEEEEEEES CS
  Glyco_hydro_12  83 ...ddt......nvkanvaydlflaaeknqv..tsigdvElmiWlarygn.iqPiGekie...tavvgGetWelwlG.....aeaeqdvlsFvak 157
                        +dt      +++ nva+d+f ++ k+++  ++i ++E+m+W+a+ygn  q iG+  +   t v++  t++l++G     ++  q+v+++va+
      EEA19401.1 199 kdvSDTpqfdsiSLNTNVAIDMFFDSLKENAtdSTIAEYEIMVWFAHYGNaAQTIGNASGivdTKVINTTTFNLYYGnhtagQNVLQHVYTWVAS 293
                     22211122332367889*******9877766456799***********9835899*9866666**************99887888999******* PP

                     S--EEEEEEHHHHHHHHH-SS-..--GGGSEE-EEEEE--B...--TT-EEEEEEEEE CS
  Glyco_hydro_12 158 spikgysfDvkdFldaltsarg..ldaedlylislqiGtEpf.tgspetlkvenfsas 212
                     ++++ +++D+   + alts+ g  ++ ++ y+  + +G E +  +  +t+ v+   ++
      EEA19401.1 294 EATELFTGDISPLITALTSKAGarYPSDKDYMGRFGFGSEAYyANQNVTFYVPKLEVD 351
                     ******************988744688999**********752677888888876665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (354 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       367  (0.0204696); expected 358.6 (0.02)
Passed bias filter:                      265  (0.0147805); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 2376.21
//
Query:       EEA19402.1  [L=803]
Description: glycosyl transferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.6e-24   86.4   0.0    4.9e-24   85.5   0.0    1.5  1  Glyco_tranf_2_3  Glycosyltransferase like family 2
    1.4e-17   64.3   0.4    1.4e-17   64.3   0.4    2.7  3  Glyco_trans_2_3  Glycosyl transferase family group 2
    1.7e-14   54.0   0.0    3.6e-14   52.9   0.0    1.6  1  Glycos_transf_2  Glycosyl transferase family 2
      7e-12   44.7   9.3    6.4e-09   34.9   0.2    3.0  4  Cellulose_synt   Cellulose synthase
    4.5e-11   42.5   0.0    7.3e-11   41.8   0.0    1.3  1  Glyco_transf_21  Glycosyl transferase family 21
     0.0013   17.5   0.1      0.017   13.7   0.0    2.2  2  Chitin_synth_2   Chitin synthase


Domain annotation for each model (and alignments):
>> Glyco_tranf_2_3  Glycosyltransferase like family 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.5   0.0   1.6e-27   4.9e-24       1     229 [.     278     512 ..     278     513 .. 0.93

  Alignments for each domain:
  == domain 1  score: 85.5 bits;  conditional E-value: 1.6e-27
  Glyco_tranf_2_3   1 prdlavlVptfneed.vlgevlesllaqeypr..vevvvvvdesdaetlevaeelaaalpdvrvrvvvnarnlgs..tgksralnealravk.. 87 
                      p+ + v++++ +e+d v+ +++++++ q+yp   ++v+v +d ++ +  + +++la ++p+v  ++  +++++g+    k+ +ln +l++++  
       EEA19402.1 278 PN-VDVFITCCGEDDeVVIDTVHAAADQDYPLdkFRVIVLDDAKSSSLEASVRQLALTYPNV--HYMARTKIPGVphHFKAGNLNYGLEQTRlm 368
                      55.789*********999************65559999999********************6..9999***998633689**********8888 PP

  Glyco_tranf_2_3  88 ....sdlvllvDdDtvvePdtlkrllqff.ltpkvgavgtpvfllnrstlvsalgalefaerhlrflaarralgvltlnGsgslirrevlkele 176
                          +++ + +D+D + e   l+++l+ +  +pk++ v  p++++n   + + ++ l f  + +      +algv+  +Gsg ++rre l++++
       EEA19402.1 369 pggaGQFMAALDADMIPEQQWLRATLPHLlIDPKMALVCPPQLFYNCPPADPLAQSLDFFVHVI--EPIKDALGVAWCTGSGYVVRREALDDIG 460
                      88889****************************************9777777778888888888..899************************* PP

  Glyco_tranf_2_3 177 gldplflltdDyelglrlrragfrtayvpgaavrevfpsslkayikqrnRwvy 229
                      ++   ++l++D+ ++  +   g+rtay  +a+ + + p++     kqr+Rw+ 
       EEA19402.1 461 QFPL-GSLAEDVATSTLMLGKGWRTAYIHEALQYGTVPEDYGGHLKQRTRWAI 512
                      ***9.**********************************************86 PP

>> Glyco_trans_2_3  Glycosyl transferase family group 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.4      0.57   1.7e+03      31      62 ..     220     251 ..     181     261 .. 0.56
   2 !   64.3   0.4   4.6e-21   1.4e-17       5     191 ..     379     564 ..     375     594 .. 0.73
   3 ?   -1.1   0.5      0.52   1.6e+03     160     182 ..     671     716 ..     634     741 .. 0.45

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.57
  Glyco_trans_2_3  31 vqgpvlvmnvanwleelaalffaedhgkdilv 62 
                      +++ +l++n an ++  a +f+a+  + +i++
       EEA19402.1 220 ITCVILAQNAANQTYAGAWVFIALELATAIPS 251
                      33444455555555555555555555555555 PP

  == domain 2  score: 64.3 bits;  conditional E-value: 4.6e-21
  Glyco_trans_2_3   5 lDaDtvlppdclreiaaela.spevaivqgpvlvm..nvanwleelaalffaedhgkdilvrealgrvvpsvGsgaflrrsalqevggwdgdes 95 
                      lDaD  + ++ lr ++ +l  +p++a+v+ p l++  + a+ l++  ++f       + +  +al +v+ ++Gsg+++rr+al+++g ++   +
       EEA19402.1 379 LDADMIPEQQWLRATLPHLLiDPKMALVCPPQLFYncPPADPLAQSLDFFVH----VIEPIKDAL-GVAWCTGSGYVVRREALDDIGQFP--LG 465
                      8*******************99*********998657778999999887763....456888888.799*********************..9* PP

  Glyco_trans_2_3  96 svsEDfdmglrlqrkGyrvrfvpeslvkekspltlraalrQrkRwayGc.....eleklil...lvrllgylgsllwsa..lplhlallllfsl 179
                      s++ED   +  ++ kG+r+ +++e+l +  +p ++  +l+Qr+Rwa G      +  k +l   +++ + ++ ++  +    + ++++ll++sl
       EEA19402.1 466 SLAEDVATSTLMLGKGWRTAYIHEALQYGTVPEDYGGHLKQRTRWAIGTvdtafK-LKFCLwgdAIKEMSFAQRFSGFLyaTLSLYTILLTASL 558
                      ************************************************7543331.22222334233333333322211002222222222222 PP

  Glyco_trans_2_3 180 lalalvllllll 191
                      +a      ++++
       EEA19402.1 559 FA------IPII 564
                      22......1111 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 0.52
  Glyco_trans_2_3 160 gsllwsal.plhlallllfslla......................l 182
                      +++l++++ ++h+a+++l+ ++                       l
       EEA19402.1 671 WTILVNYMaMFHFAFVYLTIVAVclssyrcffqndpnnfknvflcL 716
                      2222222112222222111111111133345555555555554332 PP

>> Glycos_transf_2  Glycosyl transferase family 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.9   0.0   1.2e-17   3.6e-14       1     169 [.     281     459 ..     281     460 .. 0.92

  Alignments for each domain:
  == domain 1  score: 52.9 bits;  conditional E-value: 1.2e-17
                      EEEEEESS-.TTTHHHHHHHHHHH.GGCCEEEEEEEEES-SSCHHHHHGGGCHC-TTEEEEEESS.....S-HHHHHHHHHHHH--SS...... CS
  Glycos_transf_2   1 svviptyNe.ektlletlesllaq.dpypdfeiivvDDgStDetveileelakedprvrvirree.....nvGkagalnaglraatgd...... 81 
                      +v+i+++ e  + +  t++++++q +p ++f++iv+DD+ + ++++ +++la  +p+v+++ r++      + kag+ln gl++++        
       EEA19402.1 281 DVFITCCGEdDEVVIDTVHAAADQdYPLDKFRVIVLDDAKSSSLEASVRQLALTYPNVHYMARTKipgvpHHFKAGNLNYGLEQTRLMpggagq 374
                      69*******99****************************************************9855553348************955555666 PP

                      EEEEEESSEEE-TTHHHHHHHHHHH.TTCEEEEEEEEEECCCCCCCHC-SSEEEECCHCCCCHCCCCCCSTTCSTCCCEEEEHHHHHC CS
  Glycos_transf_2  82 yilflDaDdepdpdwleklvealekdgadvvlgqrprifgetdeiernkrvgenerlyfkerkrslkgnlsfeigsaallrrealeel 169
                      +++ lDaD +p+ +wl+ ++ +l   +++++l+++p  f++  +  +  +      + + ++  ++  +++ ++gs  ++rreal+++
       EEA19402.1 375 FMAALDADMIPEQQWLRATLPHLLI-DPKMALVCPPQLFYNCPPADPLAQ--SLDFFVHVIEPIKDALGVAWCTGSGYVVRREALDDI 459
                      *************************.777999999999999999999887..79999****************************987 PP

>> Cellulose_synt  Cellulose synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.1     0.062   1.9e+02       1      45 [.     280     321 ..     280     332 .. 0.79
   2 !   15.4   0.0   1.7e-06    0.0051     165     288 ..     335     456 ..     326     460 .. 0.83
   3 !   34.9   0.2   2.1e-12   6.4e-09     405     543 ..     449     586 ..     435     599 .. 0.79
   4 ?   -5.6   1.7       3.8   1.1e+04     510     543 ..     683     716 ..     670     721 .. 0.67

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.062
  Cellulose_synt   1 vdvfvstvdplkepplvtantvlsilavdypvekvscyvsddGaa 45 
                     vdvf++      e   v  +tv +    dyp++k  + v dd  +
      EEA19402.1 280 VDVFITCCGEDDE---VVIDTVHAAADQDYPLDKFRVIVLDDAKS 321
                     5777766654444...67789999999**************9765 PP

  == domain 2  score: 15.4 bits;  conditional E-value: 1.7e-06
  Cellulose_synt 165 lprlvyvsrekrpGydhnkkaGamnalvrvsavls..napfilnldcdhyinnskalreamcfll.drelGkkvcyvqfpqrfdGidksdryanr 256
                      p + y++r k pG  h+ kaG +n  +  + ++    + f+  ld d  i + + lr ++  ll d++    ++ v  pq f    + d  a+ 
      EEA19402.1 335 YPNVHYMARTKIPGVPHHFKAGNLNYGLEQTRLMPggAGQFMAALDAD-MIPEQQWLRATLPHLLiDPK----MALVCPPQLFYNCPPADPLAQS 424
                     68999*********************99999999722567*******9.589999*****987651555....99999*************9987 PP

  Cellulose_synt 257 nvvffdinlraldGiqGpvyvGtGcvfrrqal 288
                        f  +     d +      G+G v rr+al
      EEA19402.1 425 LDFFVHVIEPIKDALGVAWCTGSGYVVRREAL 456
                     6666666555556666667789999****998 PP

  == domain 3  score: 34.9 bits;  conditional E-value: 2.1e-12
  Cellulose_synt 405 yedktewGkeiGwi.yGsvtedvltGfkmharGwrsvycvtkrdafkGsapinlsdrlhqvlrwalGsveiffsrnnalfagykkklkllerlay 498
                     y  + e  ++iG    Gs++edv t   m  +Gwr+ y         G+ p +    l+q  rwa+G+v+  f  +  l+    k++ + +r++ 
      EEA19402.1 449 YVVRREALDDIGQFpLGSLAEDVATSTLMLGKGWRTAYIHEAL--QYGTVPEDYGGHLKQRTRWAIGTVDTAFKLKFCLWGDAIKEMSFAQRFSG 541
                     6666666777875438**********************86544..46***********************************9**********85 PP

  Cellulose_synt 499 lnviiypftsifllvycilpalsllsgkfivkelsnlasiyllll 543
                     +  +   + +i l +  +  ++ l+ g+ +v   +n  + yl+  
      EEA19402.1 542 FLYATLSLYTILLTASLFAIPIILIWGRPLVAYATNEQLKYLIWA 586
                     555545555566666666666778889999988888888888754 PP

  == domain 4  score: -5.6 bits;  conditional E-value: 3.8
  Cellulose_synt 510 fllvycilpalsllsgkfivkelsnlasiyllll 543
                     f  vy ++ a++l s +   ++  n +   +l+l
      EEA19402.1 683 FAFVYLTIVAVCLSSYRCFFQNDPNNFKNVFLCL 716
                     4568899999999998877666655555555554 PP

>> Glyco_transf_21  Glycosyl transferase family 21
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.8   0.0   2.4e-14   7.3e-11      31     172 ..     373     511 ..     337     512 .. 0.79

  Alignments for each domain:
  == domain 1  score: 41.8 bits;  conditional E-value: 2.4e-14
  Glyco_transf_21  31 ydllvisDsdvrvkpdyLeellaa.ledpkvglVts..lpvgsdakglaaaleaaflntlagvlqaklsglgfavGksmalrreaLeaiGGfea 121
                       +++  +D+d++ +++ L+  l + l dpk++lV+   l ++++++   a+    f+  +   ++  + g+  ++G+ +++rreaL++iG f  
       EEA19402.1 373 GQFMAALDADMIPEQQWLRATLPHlLIDPKMALVCPpqLFYNCPPADPLAQSLDFFVH-VIEPIKD-ALGVAWCTGSGYVVRREALDDIGQFPL 464
                      5678899***********9766551568*******72255688888777766555555.5555555.68***********************98 PP

  Glyco_transf_21 122 ladeLAeDyalgkllraaGlkvvlspapiaqtsvprrsslrallaRqlrWa 172
                          LAeD a+++l+  +G++++  ++++    vp+   +   l++ +rWa
       EEA19402.1 465 --GSLAEDVATSTLMLGKGWRTAYIHEALQYGTVPE--DYGGHLKQRTRWA 511
                      ..9************************999999996..5677899999998 PP

>> Chitin_synth_2  Chitin synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0     0.042   1.3e+02      29      63 ..     282     316 ..     265     324 .. 0.83
   2 !   13.7   0.0   5.8e-06     0.017     322     420 ..     464     564 ..     453     638 .. 0.74

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.042
  Chitin_synth_2  29 clvtaysegeeglrttldslastdyddkrklllvv 63 
                     +++t+  e++e +  t+ ++a  dy+  +  ++v+
      EEA19402.1 282 VFITCCGEDDEVVIDTVHAAADQDYPLDKFRVIVL 316
                     689**********************9766555554 PP

  == domain 2  score: 13.7 bits;  conditional E-value: 5.8e-06
  Chitin_synth_2 322 llllGedrylttlllktfpkrktvfvpqakcktvaPdtfkvllsqrrrwinstvhnllel..vlvrdlcGtfcfsmrfvvfi..eligtvvlPva 412
                     l  l ed   +tl+l +    +t ++ +a    ++P+ +   l qr rw   tv   ++l   l  d    + f+ rf  f+   l    +l  a
      EEA19402.1 464 LGSLAEDVATSTLMLGK--GWRTAYIHEALQYGTVPEDYGGHLKQRTRWAIGTVDTAFKLkfCLWGDAIKEMSFAQRFSGFLyaTLSLYTILLTA 556
                     5578999999****975..6899*******************************99887732566788888888888876651133222334444 PP

  Chitin_synth_2 413 iaftlyli 420
                      +f + +i
      EEA19402.1 557 SLFAIPII 564
                     44444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (803 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       562  (0.0313459); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.71u 0.29s 00:00:01.00 Elapsed: 00:00:00.46
# Mc/sec: 5268.81
//
Query:       EEA19403.1  [L=136]
Description: DUF636 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    9.8e-25   86.7   0.0    1.3e-24   86.4   0.0    1.2  1  GFA        Glutathione-dependent formaldehyde-activating enzy
  ------ inclusion threshold ------
      0.015   15.3   0.6        0.7   10.0   0.0    2.2  2  DZR        Double zinc ribbon
       0.39   10.7   0.1       0.39   10.7   0.1    2.7  3  Nudix_N_2  Nudix N-terminal


Domain annotation for each model (and alignments):
>> GFA  Glutathione-dependent formaldehyde-activating enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.4   0.0   2.1e-28   1.3e-24       3      91 ..      27     116 ..      25     118 .. 0.97

  Alignments for each domain:
  == domain 1  score: 86.4 bits;  conditional E-value: 2.1e-28
         GFA   3 ChCsdCrkasgsaftanavvkaealellegelkeykktadsgnkvtrsfCpeCgsplyseesaapevvivrvGtlddp..eklkpeaeift 91 
                  hC+dC++++gs+++++avv+++al+ ++g +k+++ ++ sg++v+r fC+eCgsp+ ++++aape + +++Gtld    ++lkp++ei+t
  EEA19403.1  27 DHCDDCQRQTGSSYSLVAVVPKAALT-VSGPTKSWAGKGSSGKPVHRIFCSECGSPIAHDPEAAPEIIAIKAGTLDSDikKTLKPDTEIWT 116
                 5*************************.9*************************************************999**********8 PP

>> DZR  Double zinc ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.3     0.011        64      28      38 ..      26      36 ..       6      43 .. 0.68
   2 ?   10.0   0.0   0.00012       0.7      11      24 ..      71      84 ..      63     107 .. 0.81

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.011
         DZR 28 edrCpsCgekv 38
                 d+C+ C++++
  EEA19403.1 26 YDHCDDCQRQT 36
                67888888774 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00012
         DZR 11 darfCseCgtklka 24
                + +fCseCg+++  
  EEA19403.1 71 HRIFCSECGSPIAH 84
                56899999999864 PP

>> Nudix_N_2  Nudix N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.0   0.3      0.15   8.7e+02      28      33 ..       9      14 ..       7      15 .. 0.90
   2 ?   -1.2   0.4      0.33   1.9e+03      24      29 ..      28      33 ..      27      34 .. 0.73
   3 ?   10.7   0.1   6.5e-05      0.39       2      12 ..      74      84 ..      74      89 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.0 bits;  conditional E-value: 0.15
                TTEEE- CS
   Nudix_N_2 28 CgtihY 33
                Cg+++Y
  EEA19403.1  9 CGAVTY 14
                ****99 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.33
                EETTTT CS
   Nudix_N_2 24 vCpaCg 29
                 C++C+
  EEA19403.1 28 HCDDCQ 33
                588886 PP

  == domain 3  score: 10.7 bits;  conditional E-value: 6.5e-05
                B-TTT--B-EE CS
   Nudix_N_2  2 FCsqCGtpvel 12
                FCs+CG+p+++
  EEA19403.1 74 FCSECGSPIAH 84
                9*******876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (136 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       404  (0.0225333); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.38u 0.25s 00:00:00.63 Elapsed: 00:00:00.41
# Mc/sec: 991.60
//
Query:       EEA19404.1  [L=120]
Description: hypothetical protein PMAA_001990 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.18   11.9   0.1       0.35   11.0   0.1    1.4  2  UPF0258   Uncharacterised protein family (UPF0258)


Domain annotation for each model (and alignments):
>> UPF0258  Uncharacterised protein family (UPF0258)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.0      0.72   1.3e+04     104     110 ..      14      20 ..       9      23 .. 0.73
   2 ?   11.0   0.1     2e-05      0.35     111     147 ..      74     110 ..      69     114 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 0.72
     UPF0258 104 ediytPG 110
                 ed++ PG
  EEA19404.1  14 EDLFRPG 20 
                 7888887 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 2e-05
     UPF0258 111 ydsllkkkeaelkrskvckivllivllicivvvviiv 147
                  d +l +ke+   + ++c +v+   ++++++ +++++
  EEA19404.1  74 CDGMLERKERRRTQRHCCTMVAATFMVAFVCALIMLL 110
                 599***************9987655555554444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (120 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1027  (0.0572815); expected 358.6 (0.02)
Passed bias filter:                      618  (0.0344693); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.24s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 901.99
//
Query:       EEA19405.1  [L=468]
Description: FAD dependent oxidoreductase superfamily [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.8e-41  142.3   0.1    3.2e-41  142.1   0.1    1.0  1  DAO            FAD dependent oxidoreductase
    5.2e-05   22.6   0.6      0.015   14.5   0.0    2.2  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
    5.8e-05   23.1   0.4      0.007   16.4   0.1    2.3  2  NAD_binding_9  FAD-NAD(P)-binding
    0.00036   20.0   0.1     0.0079   15.5   0.0    2.1  2  Amino_oxidase  Flavin containing amine oxidoreductase
     0.0017   18.5   0.9     0.0048   17.1   0.3    2.1  2  NAD_binding_8  NAD(P)-binding Rossmann-like domain
     0.0051   16.1   0.0      0.012   14.8   0.0    1.6  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
      0.015   14.3   0.3      0.043   12.9   0.2    1.8  2  Lycopene_cycl  Lycopene cyclase protein
      0.022   14.0   0.1      0.043   13.1   0.1    1.4  1  Thi4           Thi4 family
      0.085   13.4   0.4        1.2    9.7   0.0    2.4  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
      0.097   13.2   0.0       0.22   12.1   0.0    1.5  1  YflT           Heat induced stress protein YflT
       0.21   10.4   0.1        0.3    9.8   0.1    1.2  1  MCRA           MCRA family


Domain annotation for each model (and alignments):
>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  142.1   0.1     2e-44   3.2e-41       1     351 [.      37     427 ..      37     428 .. 0.78

  Alignments for each domain:
  == domain 1  score: 142.1 bits;  conditional E-value: 2e-44
                 EEEEECTSHHHHHHHHHH....HHTT......EEEEESSSSTTSSGGGSSEEEEESSSSTHHSTH..........HHHHHHHHHHHHHHHHHHHHSST. CS
         DAO   1 dvviiGGGiiGlstAyeL....arrg......VtllekgdiagsgaSgrnsgllhsglrylpeas..........elarlslealeelreleeelgid. 78 
                 d+viiG+G++G+s Ay+L    +++g      +t+le++  ++sga+grn+g++++  ++l +            e+a++ l  ++ ++++ +++ i+ 
  EEA19405.1  37 DIVIIGAGYAGISLAYHLlksaSEAGsqdvpsITILEAR-TICSGATGRNGGHVRPDTYSLIPLYirrhglaaaaEVAEFELSHIKAIQDVIRSEKIEd 134
                 9*****************5543234578899********.5555************9854443324555556555777777777788855555556655 PP

                 TSEEEEEEEEEESSHHHHHHHHHHHHHHHHTTT...TE.EEEEHHHHHHHSTTSTTTSEE..EEETTEEEEEHHHHHHHHHHHHHHTT...-EEEESEC CS
         DAO  79 idyrrtGllslaadeeelealdkllallleagl...da.elldaeevrelepalpgllga..lfypdtgqvdpakltaalaraaealG...veilegte 168
                 +++  t  + ++ d++  ++ ++ +++l+++g    d   +++ + +++++    g++ga   f+ ++g + p+k++ +l+ra+ + G   v+i + t+
  EEA19405.1 135 CEFLLTRNMNVYLDQNRGNETKRAIEELRDQGCsfvDDiFVVSDKDAEAIS----GVKGAktAFSFTAGSIWPYKFIMGLLRAILKIGgdrVNIQTTTP 229
                 999999999998888878888888888877776443331345555466666....6777777899999***************88876355789999** PP

                 EEEEEEEETCEEEEEEECT.EEEEEEEEEEE--GGGHH.HHHTTCTTTSEEEEEEEEEEEEEECCTHSTGSGCSEEEEE..EEETTTTEEEEEETTSEE CS
         DAO 169 vtgleeedgkvwgverttp.gendaadavVnaaGawsd.llgllkeldlpispvrgqvlvlkplseklvspaailpvpe..tdddgrgvyvtprkdgrv 263
                 vt++++  ++v  v  ttp g ++a ++v+ +++a++  ll   +e  + i p++g v +++ +++ + +p ++ ++++  +d +++  y++ r+dg++
  EEA19405.1 230 VTSVSQSADGVNIV--TTPrGDIRA-KKVIHTTNAYTFgLL---PEYAPAIIPAKGIVAHIS-VPDGQ-KPPLLSQTYIlrPDAGDGADYMIVRPDGSI 320
                 ****8865555555..999998654.88********86555...7778899**********4.44423.333455555566****************** PP

                 EEEESSE..............EETTCSSTSCSHHHHHHHHHHHHHHSGG..G..CGEEEEEEEEEEE.TTSSEEEEEEETEEEEEEEEECTTTHHHHHH CS
         DAO 264 lvGgtad..............eesgdddpevdeedidellealrklfPq..l..gdvlrkwaGlrpl.pdglpligetpgvkglylatGhsghGltlap 343
                 ++Gg ++              ++++ dd++  e   d+   +++++f +  +  ++v++ w+G++    d  p ig+ p  ++ ++a+G++ghG+    
  EEA19405.1 321 IIGGAHQihtfpekgaqgnteWFGNIDDASLIESTKDYWDGYMQRYFAGweDtgAKVEELWTGIMGYsSDSAPHIGPIPSRDNQFIAAGFNGHGMPVIF 419
                 **999999***99999999999999999999999*************886534588**********648********88778************98777 PP

                 HHHHHHHH CS
         DAO 344 atGkllae 351
                 ++ k la+
  EEA19405.1 420 LSTKGLAD 427
                 77666666 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.2   0.1    0.0032       5.2       1      20 [.      39      58 ..      39      79 .. 0.82
   2 !   14.5   0.0   9.5e-06     0.015      95     137 ..     221     264 ..     217     278 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0032
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkag 20
                 +IiGaG aG++ a++l k+ 
   EEA19405.1 39 VIIGAGYAGISLAYHLLKSA 58
                 7************9987654 PP

  == domain 2  score: 14.5 bits;  conditional E-value: 9.5e-06
  Pyr_redox_3  95 elpiklfeeVesvkkedeg.fevetsketyeAkkviiAtGefdk 137
                  +++i++ + V+sv+++++g  +v+t +++++Akkvi  t  + +
   EEA19405.1 221 RVNIQTTTPVTSVSQSADGvNIVTTPRGDIRAKKVIHTTNAYTF 264
                  689************7655277888899********99988876 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.1   4.3e-06     0.007       1      39 [.      39      80 ..      39      88 .. 0.85
   2 ?    4.9   0.0     0.015        24     112     153 ..     219     259 ..     205     261 .. 0.80

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 4.3e-06
  NAD_binding_9  1 aivGaGprGlavlerLlara...kkkspleitlfdpsepgag 39
                   +i+GaG +G++++ +Ll++a    +++  +it+ + +++ +g
     EEA19405.1 39 VIIGAGYAGISLAYHLLKSAseaGSQDVPSITILEARTICSG 80
                   7*******************8766667799***999887644 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.015
  NAD_binding_9 112 pegvtvevhraevvdleeradgqavlladgaslaadaVvLAl 153
                     ++v+++  ++ v++++++adg+ ++++    ++a++V+ ++
     EEA19405.1 219 GDRVNIQ-TTTPVTSVSQSADGVNIVTTPRGDIRAKKVIHTT 259
                    5555555.3789**************************9776 PP

>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0     0.042        69       2      23 ..      46      75 ..      45      91 .. 0.91
   2 !   15.5   0.0   4.9e-06    0.0079     215     266 ..     213     265 ..     119     280 .. 0.86

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.042
                   HHHHHHHHH....HHTT....EEEEEEESS CS
  Amino_oxidase  2 aGLaaArqL....lsaG....fdVtvlEar 23
                   aG++ A++L    ++aG    +++t+lEar
     EEA19405.1 46 AGISLAYHLlksaSEAGsqdvPSITILEAR 75
                   9********999988889999999*****8 PP

  == domain 2  score: 15.5 bits;  conditional E-value: 4.9e-06
                    HHHH.TTTTEEEETSEEEEEEEEETTCEEEEETTSTEEEESEEEE-S-HHHHH CS
  Amino_oxidase 215 alae.elrgldirlntrVkeikregdgvtvtledgevveaDaVvvTvplgvlk 266
                    a+ +    +++i++ t+V+++++++dgv++ ++   +++a++V+ T+  ++  
     EEA19405.1 213 AILKiGGDRVNIQTTTPVTSVSQSADGVNIVTTPRGDIRAKKVIHTTNAYTFG 265
                    55554445689*********************999999*********998876 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   0.3   2.9e-06    0.0048       1      35 [.      40      82 ..      40      97 .. 0.78
   2 ?   -2.1   0.0       2.8   4.6e+03      41      56 ..     317     332 ..     305     338 .. 0.72

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 2.9e-06
                   EE--SHHHHHHHHHHHC....C...TE.EEEEE-SSSSSSGGG CS
  NAD_binding_8  1 IvGaGlsGlvaAylLak....a...gf.dvlllekrdrlGGra 35
                   I+GaG +G ++Ay+L k    a   ++ ++++le+r+ ++G  
     EEA19405.1 40 IIGAGYAGISLAYHLLKsaseAgsqDVpSITILEARTICSGAT 82
                   9*************987444323335578********999954 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 2.8
                    TTCEECTS---EEETT CS
  NAD_binding_8  41 pgvrvdygahifhgsg 56 
                    +g ++  gah +h++ 
     EEA19405.1 317 DGSIIIGGAHQIHTFP 332
                    6778888999999975 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   7.6e-06     0.012     142     177 ..      35      78 ..      12      85 .. 0.70
   2 ?   -3.9   0.1       3.9   6.4e+03     198     231 ..     222     255 ..     220     257 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 7.6e-06
                  TSEEEEES-SHHHHHHHHHHHHHT-........EEEEEESSSSS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxxx RF
  Pyr_redox_2 142 pkrivvvGgGyiGvElAaalaklgk........evtlveardrl 177
                  + +iv++G+Gy G+ lA +l k ++         +t++ear+++
   EEA19405.1  35 DSDIVIIGAGYAGISLAYHLLKSASeagsqdvpSITILEARTIC 78 
                  37889999999999999997555555555777777788887765 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 3.9
                  EEEEESCEEEEEEETTEEEEEEETTSCEEEESEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 198 vevklgtsvkeidgngeklevvledgeeidadlv 231
                  v++++ t v+ + +  + +  v++    i a+ v
   EEA19405.1 222 VNIQTTTPVTSVSQSADGVNIVTTPRGDIRAKKV 255
                  8889999999999888877766666666666665 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.2   2.6e-05     0.043       1      22 [.      37      58 ..      37      76 .. 0.81
   2 ?   -1.8   0.0      0.74   1.2e+03     260     320 ..      81     139 ..      63     160 .. 0.62

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.6e-05
  Lycopene_cycl  1 DvvviGaGpAglslAarlteak 22
                   D+v+iGaG Ag+slA +l +++
     EEA19405.1 37 DIVIIGAGYAGISLAYHLLKSA 58
                   9****************95443 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.74
  Lycopene_cycl 260 aiGaaaglvhPaTGYsvarslaeapllasaiaaalresslsarawatlwprerkrqreffr 320
                    a G ++g v+P T   ++  ++   l a+a +a  +    + +a ++  + e+  + ef+ 
     EEA19405.1  81 ATGRNGGHVRPDTYSLIPLYIRRHGLAAAAEVAEFE--LSHIKAIQDVIRSEKIEDCEFLL 139
                    678899999999944455566666644333333333..35556666666666666666663 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.1   2.6e-05     0.043      17      39 ..      35      57 ..      28      90 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2.6e-05
                EEEEEEE--SHHHHHHHHHHHHC CS
        Thi4 17 esDvvivGaGssGLtaayylakk 39
                +sD+vi+GaG +G++ ay l k+
  EEA19405.1 35 DSDIVIIGAGYAGISLAYHLLKS 57
                69****************99775 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.0   0.00076       1.2       2      23 ..      38      59 ..      37      75 .. 0.86
   2 ?    1.0   0.1       0.4   6.6e+02      55      77 ..     222     244 ..     216     248 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00076
                EEEECSSHHHHHHHHHHHHTTS CS
   Pyr_redox  2 vvvvGgGyiglElAgalaelgk 23
                +v++G+Gy g+ lA  l + ++
  EEA19405.1 38 IVIIGAGYAGISLAYHLLKSAS 59
                8*************99976554 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.4
                 EEEECSEEEEEEEEETTSEEEEE CS
   Pyr_redox  55 ievllntkveeiegsedgvesvk 77 
                 +++ + t v+++ +s+dgv+ v+
  EEA19405.1 222 VNIQTTTPVTSVSQSADGVNIVT 244
                 899999************88666 PP

>> YflT  Heat induced stress protein YflT
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   0.00013      0.22       7      48 ..     152     192 ..     149     210 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00013
        YflT   7 eeellsaieelkaeGyn.eddiyvvakdkdrlerlaentdaet 48 
                  +e+++aieel+++G++  ddi+vv+ +++  e++   ++a+t
  EEA19405.1 152 GNETKRAIEELRDQGCSfVDDIFVVSDKDA--EAISGVKGAKT 192
                 6899************9679*****98776..66665555555 PP

>> MCRA  MCRA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.1   0.00018       0.3       3      46 ..      37      84 ..      35      97 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00018
                EEEEE--SHHHHHHHHHHHHTT---GGG....EEEE-SS--------- CS
        MCRA  3 kaylvGsGiasLaaAvyLirdakvpgen....ihileelkvaggsldg 46
                ++ ++G+G a+++ A++L + a   g++    i+ile+ ++  g++ +
  EEA19405.1 37 DIVIIGAGYAGISLAYHLLKSASEAGSQdvpsITILEARTICSGATGR 84
                5679******************9999865666*******999988755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (468 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       351  (0.0195772); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 3233.08
//
Query:       EEA19406.1  [L=520]
Description: penicillin-binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.6e-50  171.5   1.9    1.5e-49  169.1   0.9    1.9  2  Beta-lactamase  Beta-lactamase
    3.5e-12   46.7   0.0    6.7e-12   45.8   0.0    1.5  1  DUF3471         Domain of unknown function (DUF3471)


Domain annotation for each model (and alignments):
>> Beta-lactamase  Beta-lactamase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  169.1   0.9   1.6e-53   1.5e-49      13     320 ..      30     361 ..      24     369 .. 0.86
   2 ?    1.2   0.0      0.02   1.8e+02     270     303 ..     415     444 ..     384     447 .. 0.72

  Alignments for each domain:
  == domain 1  score: 169.1 bits;  conditional E-value: 1.6e-53
                     TESEEEEEEEETTEEEEEEEEEEEETTTTEEESTTSBEEEGGGHHHHHHHHHHHHHHTT....SSCTTSBG...........GGTSTTCTTGGGT CS
  Beta-lactamase  13 gipGvavavvrdgkvvldkggGvadleggrpvtadtlfriaSvtKtftaaavlqlveeG....kldLddpV...........skylPefagpgkg 92 
                     ++pGva+avv++++++ + + G ++  ++ pvt+ tlf  +S+tK+ftaa+++ l+ ++    ++++ +pV           ++yl       ++
      EEA19406.1  30 HVPGVAIAVVDGDQTWSEGY-GISSFPST-PVTPSTLFYAGSTTKAFTAAMMATLIADNdkypHIQWTTPVsqliredfvlaDEYL-------TQ 115
                     59*************96555.99999999.**********************999888856666*******999998888888888.......99 PP

                     TEBHHHHHTTHSSCSSSSTSTTCTSHHHTH..HHHHHHHHHSBSSSSTTSCEE-SHHHHHHHHHHHHHHHTSHHHHHHHHHTTTTTTSTTEESST CS
  Beta-lactamase  93 kiTlrdLltHtsGlpdlfasdlleeaaada..aellralatlppkyapGtkwgYsntgygllgellekvtgrsleqllreeilrpLgmkdtelgp 185
                     +iTl+d l+H+ Glp++++ +   +  +d   +e++r +++lp+  + +t+++Y+n+ + ++++++  vtg+ l++ll +ei++pLgm  t + +
      EEA19406.1 116 HITLEDILSHRTGLPRHDQAYGNNNMSRDTavREIVRSIRHLPLTAELRTRFQYNNLMFVVAAHVIQSVTGEWLGDLLAREIWKPLGMEATFFSL 210
                     9*************9995555555555555**************************************************************998 PP

                     TG..GGGGGBEEEEEEETCEEECSCETTHHHHC..........TTTBEEEEHHHHHHHH...HHHHHCCSSSSHHHHHHHHHHHTSEEEECTTEE CS
  Beta-lactamase 186 pe..sgdprdaagytgngpearappanlpaeae..........gagglistardlarfl...glalegglllsaetlaqltaklssgttrpagir 265
                      +  ++d  +a+gy+ +  + ++++     + e          gag +i+++ d+a+++      l + +   +++  + ++ l + + +p++++
      EEA19406.1 211 EDalAADQDLARGYSYSYSDDDDDDEGQTEFKEvewmplneisGAGSVITNVLDYAKWArslMYKLPPLSQEVHKVIWEPRTLLPTDAEGPFTGP 305
                     65114566666666555554444444444444499************************888777777777888888888999999999999999 PP

                     EECECSSEEEEECCHTEEEEEEE..STEEEEEEEECGGTEEEEEEESBCSSHHHHHH CS
  Beta-lactamase 266 aglglGwvladktgapgtfghtG..ggygtyvfvdpeanlvvavltnrdppnedaae 320
                      ++ lGw+ + ++g  + + htG  + +g+ ++++pe +++v++l n+  + + aa+
      EEA19406.1 306 VAYALGWNTGVYQG-YQFYEHTGgmNAFGAELILFPELKYAVTILGNTAVTSNFAAK 361
                     999***********.5********************************998555554 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.02
                     CSSEEEEECCHTEEEEEEESTEEEEEEEECGGTE CS
  Beta-lactamase 270 lGwvladktgapgtfghtGggygtyvfvdpeanl 303
                        +l+ +   +gt+ h+G + +  + ++p++n+
      EEA19406.1 415 TTVPLSAY---AGTYTHPG-YQSLTITFNPQTNI 444
                     44444433...788*****.**********9998 PP

>> DUF3471  Domain of unknown function (DUF3471)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.8   0.0   7.5e-16   6.7e-12       5      95 ..     412     510 ..     408     519 .. 0.88

  Alignments for each domain:
  == domain 1  score: 45.8 bits;  conditional E-value: 7.5e-16
     DUF3471   5 nttpslpleaYvGtYedpgygtvtvslegdrLflrfdrtprlqge...LehyhgdfFlarwddrs.....seadakveFeldedgkvtrltlkaefsfd 95 
                 + +++ pl+aY+GtY++pgy+++t++   +   l++dr+ ++++e   +eh++gd F++r +++          + +eF ++ dg++ ++++  e ++ 
  EEA19406.1 412 PLPTTVPLSAYAGTYTHPGYQSLTITFNPQTNILHADRSFTTWPEcltFEHVSGDYFIIRSEHKGdlgafVPSVYPAEFVVGVDGTPRKVGVGYEEEMG 510
                 557789*******************************************************99999**99667899***********999987555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (520 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       432  (0.024095); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.26s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 3483.81
//
Query:       EEA19407.1  [L=833]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.8e-31  106.6  13.2    2.2e-24   85.7   3.2    3.6  4  DUF3433        Protein of unknown function (DUF3433)


Domain annotation for each model (and alignments):
>> DUF3433  Protein of unknown function (DUF3433)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   1.2      0.99   1.8e+04      66      82 ..     259     275 ..     254     279 .. 0.59
   2 !   35.2   2.4     7e-13   1.3e-08       1      90 [.     301     391 ..     301     392 .. 0.93
   3 ?   -1.3   0.1      0.18   3.2e+03      46      80 ..     537     577 ..     529     583 .. 0.50
   4 !   85.7   3.2   1.2e-28   2.2e-24       1      91 []     611     702 ..     611     702 .. 0.98

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 0.99
     DUF3433  66 hwlvalvslvtllsell 82 
                  w++a+ ++++l + + 
  EEA19407.1 259 PWALAIFIFLALCMIAA 275
                 46666666666664443 PP

  == domain 2  score: 35.2 bits;  conditional E-value: 7e-13
     DUF3433   1 flvsflpalvavlisllwaaldaavrrlaPFaaLahrgataersllldyratlpflallralrnrhwlvalvslvtll.sellpvlasglf 90 
                 f+ ++lp+l+a li l+   ++aa++r++PF  +a++++ +    +l+  + + +   l+++r +++lva+  l+++l + +  +l+++lf
  EEA19407.1 301 FITQYLPQLLAGLIVLWNLVIQAAIYRVMPFCIMASERQKPGVLQNLSILSRNHLIPDLSHFRYGEPLVAVGLLAIWLaNFFSMPLLACLF 391
                 7889*******************************8777777788999999***************************8888899***999 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.18
     DUF3433  46 lldyratlpflallralr......nrhwlvalvslvtllse 80 
                 l + +   +++++++ +r      +    +a++ ++  l+ 
  EEA19407.1 537 LRNESFERTLYSPFSRFRwmvwflRDYAIIAWIVIMLGLFI 577
                 55555555566777777733333233333455555555544 PP

  == domain 4  score: 85.7 bits;  conditional E-value: 1.2e-28
     DUF3433   1 flvsflpalvavlisllwaaldaavrrlaPFaaLa.hrgataersllldyratlpflallralrnrhwlvalvslvtllsellpvlasglfy 91 
                 fl+sf+p l++ +++l+w+ +d  +r l+PFa+++  +ga aers+ll+y+a+lpf + + al  +h+ va +slv++l+ +lp+l +g+f+
  EEA19407.1 611 FLFSFIPGLIGNFLFLAWQPIDVYHRALQPFASMStPEGALAERSVLLSYPACLPFEVSFLALVGKHYQVAYISLVSILFLALPILGGGVFV 702
                 99*********************************55*****************************************************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (833 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1775  (0.0990016); expected 358.6 (0.02)
Passed bias filter:                      787  (0.0438954); expected 358.6 (0.02)
Passed Vit filter:                       104  (0.00580066); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.85u 0.38s 00:00:01.23 Elapsed: 00:00:00.54
# Mc/sec: 4608.15
//
Query:       EEA19408.1  [L=493]
Description: aldehyde dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   6.7e-183  608.4   0.1   7.6e-183  608.2   0.1    1.0  1  Aldedh    Aldehyde dehydrogenase family


Domain annotation for each model (and alignments):
>> Aldedh  Aldehyde dehydrogenase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  608.2   0.1  4.2e-187  7.6e-183       6     462 .]      31     486 ..      26     486 .. 0.98

  Alignments for each domain:
  == domain 1  score: 608.2 bits;  conditional E-value: 4.2e-187
                 S.SEEEEEETTTCEEEEEEE-B-HHHHHHHHHHHHHHHH.HHTTS-HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH---HHHHHHHHHHHHHHHHHHHH CS
      Aldedh   6 s.etievinPatgeviakvpaataedvdaavaaAkeafk.awaklpaeeRaeiLrkaadlleerkeelaeletletGkplaearaeveeaidvlryyae 102
                 + +t+++inP+++++i  v++++++dvd av+aA++af+ +w+++++++R+++L ++ad le++ e  a++e+l++Gk+++ ar++v+ ++ ++ryy +
  EEA19408.1  31 AgRTFQTINPHNEKPIVAVHEGDEKDVDIAVKAARKAFEgEWKHVTPSDRGRLLVRLADFLERDLETVAAIEALDNGKSITMARNDVTASAGCFRYYGG 129
                 5367***********************************99********************************************************** PP

                 HHHHHSEEEEEECTTEEEEEEEEE-SEEEEEE-SSSCCHHHHHHHHHHHHTT-EEEEEE-TTSHHHHHHHHHHHHHTTS-TTSEEE--SSTCCHHHHHH CS
      Aldedh 103 laeklegevlpssegklalvrrePlGvvgaItPWNfPlllaawklapalaaGNtvvlKPaeetplsalllaelfeeaglPkgvlnvvtgsgsevgealv 201
                 +a+k++g+++ +++g+l+++r+eP+Gv+g+I+PWNfPll++awk+ pa+a+GNtvvlK ae+tplsal++a l++eag+P+gv+n+++g g+++g+a++
  EEA19408.1 130 WADKIYGQTIDTDSGSLTYTRHEPVGVCGQIIPWNFPLLMFAWKIGPAIATGNTVVLKTAEQTPLSALYVAALIKEAGFPPGVINIISGFGKTAGAAIA 228
                 ************99************************************************************************************* PP

                 H-TTESEEEEES-HHHHHHHHHHHH.CTTSEEEEEE---EEEEE-TTSHHHHHHHHHHHHHHGGGGTSTTSEEEEEEEHHHHHHHHHHHHHHHHT--BS CS
      Aldedh 202 ehpevdkvsftGstevgrkiakaaa.knlkrvtlElGGknplivledaDldkaveaivkgafgnaGQvCiaasrllvqesiydefveklveaakklkvg 299
                 +h +vdkv+ftGst vgr+i++ aa +nlk+vtlElGGk+p+ivl+daDl++ave++  g+f+n GQ C+a+sr+lv+e iyd+f++ ++++a++ kvg
  EEA19408.1 229 SHMDVDKVAFTGSTLVGRQILRDAAnSNLKKVTLELGGKSPNIVLPDADLEEAVEWVNLGIFFNHGQCCCAGSRILVHEAIYDKFLALFKKRAEQNKVG 327
                 ***********************5559************************************************************************ PP

                 -TTSTT-SB---SSHHHHHHHHHHHHHHHHTTSEEEE-TTE.SB-SSSTTEE--EEEES-TTTSHHHHS---SSEEEEEEESSHHHHHHHHHSSSEESE CS
      Aldedh 300 dpldedtdvGPliseaqlekvekyveeakeegaklllGgereeaglekgyfvePtvlanvtpdmriaqeEiFGPVlsvikfkdeeeaieiaNdteyGLa 398
                 dp++ +t  GP++s+ q++++++y+e++k+ gak+++Gg   +++ ++gy+++Pt++a+vt++m+i++eEiFGPV +v k+++eeeai++aN t+yGLa
  EEA19408.1 328 DPFHAETFQGPQVSQLQYDRIMGYIEDGKSCGAKVITGG---NRHGNEGYYIQPTIFADVTEKMAIVREEIFGPVCTVQKVRSEEEAIDLANRTNYGLA 423
                 ***************************************...7899***************************************************** PP

                 EEEE-SBHHHHHHHHHHS-SSEEEESSSST--TTTSEB--CGGGEES-BSHHHHHHHTEEEEEE CS
      Aldedh 399 agvftkdleraervaerleaGnvyiNdsttgaaealpfgGvkqSglGreggkegleeytevktv 462
                 a+v+t++++ a rv+++++aG+v++N+++t + ++ pfgG+k+SglGre g+++l++yte+ktv
  EEA19408.1 424 AAVHTTNINAAIRVSNAIKAGTVWVNNYNTLHYQM-PFGGFKESGLGRELGAYALDNYTEIKTV 486
                 **********************************9.**************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (493 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       400  (0.0223102); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 3225.69
//
Query:       EEA19409.1  [L=350]
Description: alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      2e-29  101.7   0.3    3.7e-29  100.8   0.3    1.5  1  ADH_N         Alcohol dehydrogenase GroES-like domain
    1.3e-23   83.4   0.4    2.3e-23   82.6   0.4    1.4  1  ADH_zinc_N    Zinc-binding dehydrogenase
    0.00014   22.9   0.0    0.00024   22.1   0.0    1.4  1  ADH_zinc_N_2  Zinc-binding dehydrogenase
     0.0089   15.4   0.1      0.024   14.0   0.2    1.6  2  2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, 
  ------ inclusion threshold ------
      0.022   14.2   1.5      0.047   13.1   1.1    1.8  2  adh_short     short chain dehydrogenase


Domain annotation for each model (and alignments):
>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.8   0.3     1e-32   3.7e-29       1     108 [.      31     139 ..      31     140 .. 0.96

  Alignments for each domain:
  == domain 1  score: 100.8 bits;  conditional E-value: 1e-32
                 TTEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS--TT-EEEE-SEEE.-SSSHHHHTT-GGG-TTBEETTTSS-SSSBSE CS
       ADH_N   1 pgevlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkklkvGdrVvveplis.cgeCaaCkegeenlCeeakllgvsldGgfaey 98 
                 p+++l+++ ++g+C++Dlh + g++ l+vk+pl+ GHE +G+v++ g+ v+++++Gd+  v++l   c +C+ C++ +e lC++a+l g+++dG+f++y
  EEA19409.1  31 PDQILVRILYSGVCHTDLHAMMGHWPLPVKMPLVGGHEGAGVVVAKGSLVHEFEIGDHAGVKWLNGsCLDCEFCRQSHEPLCADAELSGYTVDGTFQQY 129
                 589***********************************************************99877******************************** PP

                 EEECGGGEEE CS
       ADH_N  99 vvvpekklvk 108
                 ++++++++ k
  EEA19409.1 130 TLAKAAHASK 139
                 ****998766 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.6   0.4   6.5e-27   2.3e-23       1     129 [.     182     312 ..     182     313 .. 0.95

  Alignments for each domain:
  == domain 1  score: 82.6 bits;  conditional E-value: 6.5e-27
                 HHHHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTESEEEETTTC.HHHHHHHHHT.TTSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSC.TSSEEE CS
  ADH_zinc_N   1 gvGlaavqlAkalGaeviavdsseeklelakklGadevinykea.dlverikelt.ggegvdvvfecvGsgatleaalkllkpgGrlvvvGg.gkgeee 96 
                 g+G++a q+Aka+G +v+avd+ +ek+ ++++lGa+++++ ++  d+v+++k++t g  g+++v+  + s++ +++a ++++ +G++v +G+ +    +
  EEA19409.1 182 GLGSLAQQYAKAMGLRVVAVDGGDEKRTMCEQLGAEAYVDFTKSkDVVADVKAATpGCLGAHAVILLAVSEKPFQQAAEYVRSHGTIVAIGLpPDAYLK 280
                 89***************************************8888**********557899999999999**********************9999999 PP

                 EEHHHHHHTT-EEEEE-SSCHHHHHHHHHHHHH CS
  ADH_zinc_N  97 fdlrnlllkeksilGsllgslreefkealdlla 129
                  +++n + + ++i+Gs +g+ r++  eald++a
  EEA19409.1 281 APVFNAVVRMITIKGSYVGN-RQDGVEALDFFA 312
                 ********************.999999999986 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.1   0.0   6.8e-08   0.00024       1     133 []     214     346 ..     214     346 .. 0.77

  Alignments for each domain:
  == domain 1  score: 22.1 bits;  conditional E-value: 6.8e-08
                   TT-SEEEETT.STTHH....HHH-T..T-EEEEEES-HHHHH.HHHHHHEEEEEEEEE----.S-EEE-CHHHCTTT-EEEE--GGG...-.-HHHH CS
  ADH_zinc_N_2   1 lGAdevidyr.tedfe....aatgg..egvDvvldtvggealleaslkvlpggGrlvsiggpplsaallkpakkrkgrsvkyeflfsmkasaqadil 90 
                   lGA+  +d + ++d++    aat g  ++  v+l +v  + + +++ ++++ +G++v ig pp  a l +p +++  r ++++    +   +++d  
    EEA19409.1 214 LGAEAYVDFTkSKDVVadvkAATPGclGAHAVILLAVSEKPF-QQAAEYVRSHGTIVAIGLPP-DAYLKAPVFNAVVRMITIKGSY-VG--NRQD-G 304
                   788888888878888888874443354667788888999999.9999***888*******753.4444555555655555555555.33..4677.8 PP

                   HHHHHHHHHHH----EEEEEEGGGHHHHHHHHHSS--SSEEEE CS
  ADH_zinc_N_2  91 eelaalieeGklrpvvdrvfpleeaaeAhrylesgrarGKiVl 133
                    e +++++ G ++ +   v pl+++++ + ++e+g+  G+ Vl
    EEA19409.1 305 VEALDFFARGLIKAPFK-VAPLADLPKIYHLMEKGQIAGRYVL 346
                   9*************997.**********************997 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       1.1     4e+03     126     153 ..      74     101 ..      72     119 .. 0.73
   2 !   14.0   0.2   6.6e-06     0.024      36      82 ..     171     219 ..     162     237 .. 0.81

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 1.1
                   SS-GGGB-HHHHHHHHHTTSCCEEEES- CS
  2-Hacid_dh_C 126 taRGglvdeeaLleaLksgkiagaalDv 153
                   +a+G+lv+e  + +    +++ g  lD+
    EEA19409.1  74 VAKGSLVHEFEIGDHAGVKWLNGSCLDC 101
                   7899999999999988888888888886 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 6.6e-06
                   TSEEEEES-S.HHHHHHHHHHHHTT-EEEEESSSHHHHHCHHHHTC.EE CS
  2-Hacid_dh_C  36 gktvGiiGlG.rIGqavakrlkafgmkviaydrskkkeeeeeelgv.el 82 
                   g+tv+i+G+G  +G+ + +++ka+g++v+a+d   +k++ +e+lg+  +
    EEA19409.1 171 GETVAIVGAGgGLGSLAQQYAKAMGLRVVAVDGGDEKRTMCEQLGAeAY 219
                   89******9637********************99888777777777333 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   1.1   1.3e-05     0.047       2      61 ..     173     225 ..     172     242 .. 0.78
   2 ?   -2.8   0.0         1   3.6e+03      26      47 ..     243     265 ..     239     276 .. 0.66

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.3e-05
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSH CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdr 61 
                 +v ++Ga++G+G    +   ++G +vv+vd  +ek  +++++l++e+       vD t++
  EEA19409.1 173 TVAIVGAGGGLGSLAQQYAKAMGLRVVAVDGGDEKR-TMCEQLGAEA------YVDFTKS 225
                 799*********9888888899**********9988.9999999873......3333333 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1
                 EEEE.EESCHHHHHHHHHHHHHT CS
   adh_short  26 kvvv.vdrseekleevakelkee 47 
                 + v+ ++ se++ +++a+ ++++
  EEA19409.1 243 HAVIlLAVSEKPFQQAAEYVRSH 265
                 44444888888888888777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (350 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       372  (0.0207485); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 2353.24
//
Query:       EEA19410.1  [L=291]
Description: transcriptional activator of ethanol catabolism AlcS [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.1e-33  115.2  17.9    3.8e-33  114.8  17.9    1.1  1  Gpr1_Fun34_YaaH  GPR1/FUN34/yaaH family


Domain annotation for each model (and alignments):
>> Gpr1_Fun34_YaaH  GPR1/FUN34/yaaH family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.8  17.9   2.1e-37   3.8e-33      10     205 ..      48     260 ..      40     262 .. 0.93

  Alignments for each domain:
  == domain 1  score: 114.8 bits;  conditional E-value: 2.1e-37
  Gpr1_Fun34_YaaH  10 apvpkrkfaNPaPlgllafalttfvlslvnlgargitepn.vvvglalfyGGlvqllaGiwefavgntFgatalssYGgFwlsyaailipgfgi 102
                      +p  +++++NP Pl l +f +tt  ls+  +  rg   +  +++g ++f+GGl  l++ i+ef+ gntF+++++ + G+Fwl+yaa +ip+f+ 
       EEA19410.1  48 QPKLTKQLGNPTPLALGGFVITTTPLSCALMAWRGAGGNGlAFIGSFVFLGGLLVLITSILEFILGNTFSCVVFGTVGSFWLAYAATMIPSFNA 141
                      5777899****************************986651689************************************************** PP

  Gpr1_Fun34_YaaH 103 laaY.........eedeeelnnalglyllgwfiftfllllatlrstvalfllfffldltflllaigeltgsak.......vlkAggvfgiiaaf 180
                      +a Y            + ++++++++ +++ +i+++++l++++r++++ +++ff+l   f+lla+g+ t  ++       ++k +g++ +++++
       EEA19410.1 142 VAPYsatlnntaaGMASPQFQDTFAFLFITMAILMLVFLICSTRTNLVYAIIFFLLIPVFCLLAAGDWTLAEGnedasvrCIKGAGALLFASSL 235
                      ******999887655667*************************************************9776666789999************** PP

  Gpr1_Fun34_YaaH 181 lawYnalaglatkensyftlpvipl 205
                      l++Y  ++ l+++ +  f+lpv +l
       EEA19410.1 236 LGFYLLTSVLLESLQFPFRLPVGDL 260
                      ************99999***99877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (291 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       949  (0.052931); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 1931.31
//
Query:       EEA19411.1  [L=291]
Description: transcriptional activator of ethanol catabolism AlcS [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.1e-33  115.2  17.9    3.8e-33  114.8  17.9    1.1  1  Gpr1_Fun34_YaaH  GPR1/FUN34/yaaH family


Domain annotation for each model (and alignments):
>> Gpr1_Fun34_YaaH  GPR1/FUN34/yaaH family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.8  17.9   2.1e-37   3.8e-33      10     205 ..      48     260 ..      40     262 .. 0.93

  Alignments for each domain:
  == domain 1  score: 114.8 bits;  conditional E-value: 2.1e-37
  Gpr1_Fun34_YaaH  10 apvpkrkfaNPaPlgllafalttfvlslvnlgargitepn.vvvglalfyGGlvqllaGiwefavgntFgatalssYGgFwlsyaailipgfgi 102
                      +p  +++++NP Pl l +f +tt  ls+  +  rg   +  +++g ++f+GGl  l++ i+ef+ gntF+++++ + G+Fwl+yaa +ip+f+ 
       EEA19411.1  48 QPKLTKQLGNPTPLALGGFVITTTPLSCALMAWRGAGGNGlAFIGSFVFLGGLLVLITSILEFILGNTFSCVVFGTVGSFWLAYAATMIPSFNA 141
                      5777899****************************986651689************************************************** PP

  Gpr1_Fun34_YaaH 103 laaY.........eedeeelnnalglyllgwfiftfllllatlrstvalfllfffldltflllaigeltgsak.......vlkAggvfgiiaaf 180
                      +a Y            + ++++++++ +++ +i+++++l++++r++++ +++ff+l   f+lla+g+ t  ++       ++k +g++ +++++
       EEA19411.1 142 VAPYsatlnntaaGMASPQFQDTFAFLFITMAILMLVFLICSTRTNLVYAIIFFLLIPVFCLLAAGDWTLAEGnedasvrCIKGAGALLFASSL 235
                      ******999887655667*************************************************9776666789999************** PP

  Gpr1_Fun34_YaaH 181 lawYnalaglatkensyftlpvipl 205
                      l++Y  ++ l+++ +  f+lpv +l
       EEA19411.1 236 LGFYLLTSVLLESLQFPFRLPVGDL 260
                      ************99999***99877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (291 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       949  (0.052931); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.49
# Mc/sec: 1793.96
//
Query:       EEA19412.1  [L=136]
Description: hypothetical protein PMAA_002060 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (136 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       246  (0.0137208); expected 358.6 (0.02)
Passed bias filter:                      222  (0.0123822); expected 358.6 (0.02)
Passed Vit filter:                         8  (0.000446204); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.31s 00:00:00.74 Elapsed: 00:00:00.47
# Mc/sec: 860.81
//
Query:       EEA19413.1  [L=320]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.6e-38  130.5   3.8    4.6e-38  130.5   3.8    1.7  2  Ferritin_2  Ferritin-like domain


Domain annotation for each model (and alignments):
>> Ferritin_2  Ferritin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  130.5   3.8   2.6e-42   4.6e-38       1     133 [.      34     167 ..      34     170 .. 0.98
   2 ?   -1.7   0.0      0.17     3e+03      61      72 ..     232     245 ..     199     279 .. 0.72

  Alignments for each domain:
  == domain 1  score: 130.5 bits;  conditional E-value: 2.6e-42
  Ferritin_2   1 sdvdiLnfAlnlEyleaafYtaalegasldd..kalldaevrevaeeiakheeaHveflkaale..GaaavakptfdfafdpfadeksflalaavlEdv 95 
                 sd+diL+fAl+lE+le++fY++al+++s++d  +a+++++ +  +e ia++ee+Hv +l++a++  Gaa+va+++++f   p++d +sf++la v+E v
  EEA19413.1  34 SDIDILQFALTLEHLENTFYKQALSKFSQADftSAGFNEAFLINLEFIAHDEEQHVVLLQSAISqaGAAPVASCQYNF---PITDVTSFVNLATVFEGV 129
                 69**************************999***********************************************...****************** PP

  Ferritin_2  96 gvsAYlgaapllsnkelltaaasIlsvEArHaavirtl 133
                 gvsAYlgaa+ +s+k++l++aa I   E  H+a+ r+ 
  EEA19413.1 130 GVSAYLGAATAISSKAILNVAAAITVSEGLHQAIQRAS 167
                 *********************************98875 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.17
  Ferritin_2  61 le..Gaaavakptf 72 
                 l+  G++a+++p+f
  EEA19413.1 232 LTvaGGTAIPSPAF 245
                 22337777777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (320 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       565  (0.0315132); expected 358.6 (0.02)
Passed bias filter:                      381  (0.0212505); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 2102.20
//
Query:       EEA19414.1  [L=227]
Description: hypothetical protein PMAA_002080 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (227 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       379  (0.0211389); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.27s 00:00:00.69 Elapsed: 00:00:00.42
# Mc/sec: 1609.69
//
Query:       EEA19415.1  [L=858]
Description: C6 transcription factor AlcR [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00024   21.1   0.8    0.00068   19.7   0.8    1.7  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.8   3.8e-08   0.00068      19      39 ..     113     133 ..     102     134 .. 0.86

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 3.8e-08
                 S-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus  19 aCsnCkklnleCtfysesskr 39 
                 aC nCk++ +eCtf++ ssk+
  EEA19415.1 113 ACYNCKRWKKECTFNWLSSKE 133
                 4*****************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (858 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       621  (0.0346366); expected 358.6 (0.02)
Passed bias filter:                      484  (0.0269954); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.28s 00:00:00.96 Elapsed: 00:00:00.44
# Mc/sec: 5827.98
//
Query:       EEA19416.1  [L=490]
Description: MFS quinate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.3e-90  302.8  16.9    7.5e-90  302.0  16.9    1.3  1  Sugar_tr    Sugar (and other) transporter
    5.4e-25   88.1  31.3    6.9e-25   87.7  31.3    1.1  1  MFS_1       Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.055   13.3   0.2        0.1   12.4   0.2    1.3  1  Nop52       Nucleolar protein,Nop52
       0.93    7.7   7.8        1.1    7.4   6.6    1.9  1  OATP        Organic Anion Transporter Polypeptide (OATP) fami


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  302.0  16.9   1.7e-93   7.5e-90      44     414 ..      42     441 ..       9     454 .. 0.92

  Alignments for each domain:
  == domain 1  score: 302.0 bits;  conditional E-value: 1.7e-93
                 ...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHH CS
    Sugar_tr  44 ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvsl 142
                  ++ +g+++s++++G+i+Gsl ag+lg++f+Rk+++ +a+  ++ g+ l   a+ +    +l++gR+++G+gvGl+s++ P+y +E+A ++lRg lvs+
  EEA19416.1  42 FASAQGWLTSVLQLGGIVGSLSAGILGEIFSRKYTMFMACCWVILGSYLYCGAH-AGDPSLLYAGRFFTGLGVGLFSGVGPLYNAELASPELRGLLVSF 139
                 56789*************************************************.55****************************************** PP

                 HHHHHHHHHHHHHHHHHHHHTSS-......TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHHTT-HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH CS
    Sugar_tr 143 yqlaitfGilvaaifglglnktsn......adgwrillglqlvpallllilllflPESPrylvekgkeeeakevlaklrgeedadrelaeekdsleaeq 235
                 yq+a+++G++ a+++g+g n++++      +  w+++  +q +pa ll+++++++P SPr+lv+kg+ eea+++la+lr+ + +d  ++ e+ +++ae 
  EEA19416.1 140 YQFATILGMMSAFWIGYGSNNIGGtgdtqsNLAWQLPSIIQGIPACLLALGIWWMPFSPRWLVKKGRVEEARKTLAWLRKLPIDDAMVQVEFLEIQAEA 238
                 ********************99999***99999************************************************999999999999999998 PP

                 H......................HTTHHHHSH.........HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH...HHHHHHHHHHHHHHHHHHH CS
    Sugar_tr 236 eee.................kaswkellsskt......vrqrlligvvlqifqqltGinaimyysptifenlglsks...llvtiivgvvnfvatfvai 308
                   e                 ++  +el + ++      +++r+ ++ ++++fqq +Gi +i+yy++++f +lgl++    ll+t+++gvv fv t+ a+
  EEA19416.1 239 LFEqrafakafpdlaarenqNVLFRELAQYVNcvrtkdNFKRVATAWLVMFFQQWSGIDSIIYYASEVFVSLGLNTGtvaLLATGVTGVVFFVCTIPAM 337
                 8888999***********995555555555555555559*************************************99********************* PP

                 HHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHH CS
    Sugar_tr 309 flvdrfGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfp 407
                 +++d++GR+++ll G+  m++++vi+g +++ +++  ++   ++ ++i ++i  f+++wgpv w lvsE+fp+s+R+k+++i +++nw+ nf+i+l+ p
  EEA19416.1 338 LVIDKVGRKPMLLAGSGLMFAAMVIVGVIVAKFRH--DWEHHAVAALIWVYIGTFGATWGPVSWTLVSEIFPLSIRAKGASIGAFSNWINNFAIALFVP 434
                 ***************************44444444..499*********************************************************** PP

                 HHHCHHH CS
    Sugar_tr 408 iiteaig 414
                  +++a  
  EEA19416.1 435 PMFDAWA 441
                 ***9876 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.7  31.3   1.5e-28   6.9e-25      32     351 ..      44     431 ..      26     433 .. 0.83

  Alignments for each domain:
  == domain 1  score: 87.7 bits;  conditional E-value: 1.5e-28
       MFS_1  32 seigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfa.sslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraiglls 127
                 s++g+l+++  lg +v+sl +G l++ f+r+ +++++  + +lg  l++  a ++ + ll+++r+++Glg g++  +g  + a+++++e rg+ +++++
  EEA19416.1  44 SAQGWLTSVLQLGGIVGSLSAGILGEIFSRKYTMFMACCWVILGsYLYCG-AhAGDPsLLYAGRFFTGLGVGLFSGVGPLYNAELASPELRGLLVSFYQ 141
                 689*************************9999888888888888556666.3499999***************************************** PP

       MFS_1 128 agfslGailgpllggllasslg.........Wravfyilaivsllafvlfllllpeepperkrkspkeee............................. 188
                  ++ lG++ +  +g      +g         W+++ +i +i ++l+++ +++++p +p+   +k  +ee                              
  EEA19416.1 142 FATILGMMSAFWIGYGSNNIGGtgdtqsnlaWQLPSIIQGIPACLLAL-GIWWMPFSPRWLVKKGRVEEArktlawlrklpiddamvqvefleiqaeal 239
                 *************999997777***********************988.66***9999999999999999999*******************9999999 PP

       MFS_1 189 ..................kgtgpaplvp....awkallkdpvlw....illialllfffgfsglltllplylqevlgls.glllaglllallalvgail 260
                                   + +               ++++  +     ++l++++  + g+ ++ ++        lgl+ g   a+l+ +++++v+++ 
  EEA19416.1 240 feqrafakafpdlaarenQNVLF----RelaqYVNCVRTKDNFKrvatAWLVMFFQQWSGIDSIIYYASEV-FVSLGLNtG-TVALLATGVTGVVFFVC 332
                 97666666666666544433333....14445777777777774334567777777777777766666664.788888885.55555699999999999 PP

       MFS_1 261 allagrlsdrlgrrrrlllallllllaalglallavt......ssavllllvlvliGfglgfvfpsllalasdlapp..eeagtasglfn.tagslgga 350
                  + a  ++d++gr+++ll + +l+++a +++ ++ +       +  ++++l+ v iG+++++  p +++l+s+ +p   ++ g+ +g+f+  ++++++a
  EEA19416.1 333 TIPAMLVIDKVGRKPMLLAGSGLMFAAMVIVGVIVAKfrhdweH-HAVAALIWVYIGTFGATWGPVSWTLVSEIFPLsiRAKGASIGAFSnWINNFAIA 430
                 99999999*****9999999999999999998888889898843.444444677788888888899999999999775577778888888788888887 PP

       MFS_1 351 l 351
                 l
  EEA19416.1 431 L 431
                 7 PP

>> Nop52  Nucleolar protein,Nop52
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.2   2.3e-05       0.1      58      99 ..     257     298 ..     254     300 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2.3e-05
       Nop52  58 vQqelaeeLaelvkslkskeaalkFlkafwetmsreWkgiDk 99 
                  Q+ l +eLa+ v+++++k+++ +  +a + +  ++W+giD 
  EEA19416.1 257 NQNVLFRELAQYVNCVRTKDNFKRVATAWLVMFFQQWSGIDS 298
                 6999*************99999999999999999*******7 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   6.6   0.00025       1.1     134     251 ..     101     212 ..      73     397 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.00025
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 134 lfflaqlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllklyvdidseisltpkdprWvgaWWlgflilgvllllaaip 232
                 l+ ++ ++ G+G  ++  +G  Y  + ++++   l+++++++++ilG++ +f +G+  +++  +          d++   aW l  +i g+ ++l+a+ 
  EEA19416.1 101 LLYAGRFFTGLGVGLFSGVGPLYNAELASPELRGLLVSFYQFATILGMMSAFWIGYGSNNIGGT---------GDTQSNLAWQLPSIIQGIPACLLALG 190
                 7899****************************************************99996543.........47777889999999999999999999 PP

                 xxxxxxx...xxxxxxxxxxxx RF
        OATP 233 lffFPke...lpkkkeerakkk 251
                 +++ P +   l kk + ++++k
  EEA19416.1 191 IWWMPFSprwLVKKGRVEEARK 212
                 9988877666444444444433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (490 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       730  (0.0407162); expected 358.6 (0.02)
Passed bias filter:                      399  (0.0222544); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.62u 0.28s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 3261.37
//
Query:       EEA19417.1  [L=413]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.9e-21   75.1   0.7      1e-20   74.3   0.7    1.4  1  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma
     0.0085   16.0   0.1      0.016   15.1   0.1    1.4  1  KR               KR domain
  ------ inclusion threshold ------
      0.015   15.3   0.0      0.031   14.3   0.0    1.6  1  Shikimate_DH     Shikimate / quinate 5-dehydrogenase
      0.031   14.7   0.1       0.09   13.2   0.0    1.9  2  Semialdhyde_dh   Semialdehyde dehydrogenase, NAD binding doma


Domain annotation for each model (and alignments):
>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.3   0.7   2.2e-24     1e-20       1     130 []      12     142 ..      12     142 .. 0.96

  Alignments for each domain:
  == domain 1  score: 74.3 bits;  conditional E-value: 2.2e-24
                      EEEE--.SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHH.....TTTCEEEEE--TTTHHHHHHHHHTTSSEEEE-SSGG.GHHHHHH CS
  Sacchrp_dh_NADP   1 vliiGa.GsvGqavaellarhfdvdaeitvadrskeklealaaka.....lgvrfeaialdaenyeavLaallkegdlvvnlsppi.ssldvlk 87 
                      ++++Ga G++G+ +a  +a++ +   ++++a+rs +kl+ala+++      + + e++ +d+e++++ L+al++ ++++++++ +   +++v++
       EEA19417.1  12 IVLVGAtGYTGRLTAYHIAQNLPTNLKWAIAGRSSAKLDALADELkhiseDRLQPEIEIVDIEDKAQ-LTALVARAKVCISVVSYNeVGANVIE 104
                      899********************988*****************999998888888999*********.******************9999**** PP

                      HHHHHT-EEEESS-BCGCCSCHCCSHHHHHTHHHHHHCTSEEE CS
  Sacchrp_dh_NADP  88 aCietgvhyvdtsiskeertnyalreavlklkekakeagvtav 130
                      aCie +++yvdts      +  +lre++ k++++a++a+v ++
       EEA19417.1 105 ACIESRTNYVDTSG-----SIAHLREWIDKYHQAAEQANVAII 142
                      ***********999.....8999****************9886 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.1   3.5e-06     0.016       4      76 ..      13      87 ..      11      94 .. 0.91

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 3.5e-06
                EEETTTSHHHHHHHHHHHHHHS-EE..EEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHH CS
          KR  4 litGGlGgLGlelarwlaekgarhl..vllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeik 76
                +++G++G  G+ +a ++a++  ++l  ++ +Rs+a+ ++ +++++++++   + e+  +D+ dk++++al++++k
  EEA19417.1 13 VLVGATGYTGRLTAYHIAQNLPTNLkwAIAGRSSAKLDALADELKHISEDRLQPEIEIVDIEDKAQLTALVARAK 87
                689****************9977765589****999999999****************************99876 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   6.9e-06     0.031       7      59 ..       4      59 ..       1     101 [. 0.81

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 6.9e-06
                  HS..TT-EEEEES-.SHHHHHHHHHHHCCT-CEE..EEEESSHHHHHHHHHHHT.E CS
  Shikimate_DH  7 leslkekkvlliGa.GemaelvakhLlakgvkkv..vvaNRtlerakelaeelkge 59
                  +++++e  ++l+Ga G +++l+a h++++  +++  ++a+R+ ++ ++la+elk+ 
    EEA19417.1  4 TKNHREYDIVLVGAtGYTGRLTAYHIAQNLPTNLkwAIAGRSSAKLDALADELKHI 59
                  56778899*****88*************966654339***************9654 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0     2e-05      0.09       2      80 ..      12      90 ..      11     127 .. 0.65
   2 ?   -3.0   0.0       2.1   9.3e+03      25      45 ..     329     349 ..     324     355 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 2e-05
                    EEEETTTSHHHHHHHHHHHCTSSEEEEEEEESTTTTTSBHHHHSGGGTTTECEBEEE.GGGGGC.TT-SEEEE-SCHHHHH CS
  Semialdhyde_dh  2 vaivGatGyvGqellrlLeehpevelvvllsssrsaGkklaeavkaleegkdlkved.vdeeel.kevdivflalpagvsk 80
                    + +vGatGy+G+  +  ++++ + +l ++++ ++sa  kl++++ +l+++++ ++++ +++ ++ +++++  l + a+v+ 
      EEA19417.1 12 IVLVGATGYTGRLTAYHIAQNLPTNLKWAIAGRSSA--KLDALADELKHISEDRLQPeIEIVDIeDKAQLTALVARAKVCI 90
                    679********************9999999988855..4444444455555555555333333334444444444444444 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 2.1
                     EEEEEEEESTTTTTSBHHHHS CS
  Semialdhyde_dh  25 velvvllsssrsaGkklaeav 45 
                     ve+ +l+  +++aG+++ +a+
      EEA19417.1 329 VEMEALAVADSEAGSTVPKAY 349
                     666666666666999998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (413 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       561  (0.0312901); expected 358.6 (0.02)
Passed bias filter:                      510  (0.0284455); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.55u 0.26s 00:00:00.81 Elapsed: 00:00:00.42
# Mc/sec: 2950.07
//
Query:       EEA19418.1  [L=583]
Description: hypothetical protein PMAA_002120 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.1e-05   23.4   0.3    0.00011   22.1   0.3    1.7  1  F-box-like  F-box-like
    0.00098   19.0   0.3      0.003   17.4   0.3    1.8  1  F-box_4     F-box
  ------ inclusion threshold ------
      0.023   14.6   2.2       0.17   11.8   0.9    2.7  2  F-box       F-box domain
      0.099   12.7   0.0       0.21   11.6   0.0    1.5  1  NCD1        NAB conserved region 1 (NCD1)


Domain annotation for each model (and alignments):
>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.1   0.3   2.4e-08   0.00011       2      38 ..      35      73 ..      34      76 .. 0.86

  Alignments for each domain:
  == domain 1  score: 22.1 bits;  conditional E-value: 2.4e-08
  F-box-like  2 srLPdEiLlqIFsyLpps..dLlrlalVCrrWrrvaldt 38
                ++LP EiL++I  y+++   +L++lalV ++ r++a+++
  EEA19418.1 35 LNLPVEILSEIVKYIETDksSLASLALVNSDCRQLARSC 73
                69************9533359**************9887 PP

>> F-box_4  F-box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.3   6.7e-07     0.003       2      41 ..      31      72 ..      30      82 .. 0.90

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 6.7e-07
     F-box_4  2 edsLssLPlevlqhiaslL..DsfsLsqLslvskllrevcss 41
                ++sL +LP+e+l +i++++  D+ sL +L+lv++  r++++s
  EEA19418.1 31 NSSLLNLPVEILSEIVKYIetDKSSLASLALVNSDCRQLARS 72
                57899************986699***************9987 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.9   3.7e-05      0.17       2      42 ..      33      75 ..      32      79 .. 0.92
   2 ?    0.7   0.0      0.12   5.2e+02      12      28 ..     407     423 ..     407     452 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3.7e-05
                HHHHS-HHHHHHHHHTS-HHH..HHHHCTT-HHHHHHHTTHHH CS
       F-box  2 tlsrLPsevlrhILerLplsd..llalrrVSkgwrilidsdrl 42
                +l++LP e+l +I ++ ++    l +l++V   +r+l +s+ +
  EEA19418.1 33 SLLNLPVEILSEIVKYIETDKssLASLALVNSDCRQLARSCQF 75
                79**************9999999**************999765 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.12
                 HHHHHTS-HHHHHHHCT CS
       F-box  12 rhILerLplsdllalrr 28 
                 ++I++++ l++l +l++
  EEA19418.1 407 EKIISSVTLMSLSRLSS 423
                 57888888888888885 PP

>> NCD1  NAB conserved region 1 (NCD1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   4.8e-05      0.21       8      72 ..     468     532 ..     463     535 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 4.8e-05
        NCD1   8 lqlyrvLqranLlqYydvliaqGGDdveqlleaeeeefleimelvGmaskPLhvrRlqkaLqewv 72 
                 +q+ + L  a+  +Yyd  +  G D +e + + +  +  ++++ +      Lh+rR+ +  ++++
  EEA19418.1 468 YQINKQLPNAEENSYYDYRVPSGDDYIEFMEQQQSADDGQVIDSLHDVWEKLHLRRMTQQAEKYA 532
                 6788889999999*******************9999******999999999******99888775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (583 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       439  (0.0244855); expected 358.6 (0.02)
Passed bias filter:                      375  (0.0209158); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.42
# Mc/sec: 4175.24
//
Query:       EEA19419.1  [L=214]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (214 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1201  (0.0669864); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.49
# Mc/sec: 1312.14
//
Query:       EEA19420.1  [L=749]
Description: G-patch domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    8.6e-13   48.0   1.1    1.8e-12   46.9   1.1    1.5  1  G-patch    G-patch domain
    1.6e-09   36.9   3.4    2.8e-09   36.1   3.4    1.4  1  zf-RanBP   Zn-finger in Ran binding protein and others
    1.1e-08   34.8   0.3    0.00013   21.7   0.0    2.8  3  RRM_1      RNA recognition motif. (a.k.a. RRM, RBD, or RNP do
    8.7e-08   32.1   0.2    2.5e-07   30.7   0.2    1.8  1  G-patch_2  G-patch domain
     0.0038   16.9   1.0     0.0038   16.9   1.0    2.2  3  RED_N      RED-like protein N-terminal region
  ------ inclusion threshold ------
       0.99    9.4   6.9        1.9    8.5   2.2    2.3  2  NCD3G      Nine Cysteines Domain of family 3 GPCR


Domain annotation for each model (and alignments):
>> G-patch  G-patch domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.9   1.1   6.1e-16   1.8e-12       3      44 ..     669     710 ..     668     711 .. 0.97

  Alignments for each domain:
  == domain 1  score: 46.9 bits;  conditional E-value: 6.1e-16
     G-patch   3 niGvkmLqkmGWkpGqGLGkkeqGiaePieakikkdraGlGa 44 
                 ++G+ +L+kmGW++G+GLG ++ G+++Pi +++  ++ GlGa
  EEA19420.1 669 SKGAALLSKMGWSEGSGLGAQGTGMTTPIATDVYAQGVGLGA 710
                 79***************************************9 PP

>> zf-RanBP  Zn-finger in Ran binding protein and others
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.1   3.4   9.5e-13   2.8e-09       1      28 [.     271     298 ..     271     300 .. 0.95

  Alignments for each domain:
  == domain 1  score: 36.1 bits;  conditional E-value: 9.5e-13
                 GSSSEE-SSS--EEESSSSB-TTT--BT CS
    zf-RanBP   1 regdWdCskClvqNfawstkCvaCqapk 28 
                 +eg W+C  C++ Nfa+++kC++Cqa +
  EEA19420.1 271 PEGEWTCRNCSFENFATRQKCFRCQADR 298
                 59************************87 PP

>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.0   0.0   0.00019      0.57      25      57 ..     201     234 ..     190     243 .. 0.90
   2 !   21.7   0.0   4.4e-08   0.00013      23      62 ..     385     425 ..     382     429 .. 0.92
   3 ?   -3.9   0.1       4.3   1.3e+04      48      61 ..     605     618 ..     604     620 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00019
                 EEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHH CS
       RRM_1  25 iksiklvrd.etgkskgfafVeFeskedAekAle 57 
                  ++++++rd +t+ s+ ++f +F s  d ++ +e
  EEA19420.1 201 LEDVRVIRDrQTKISRQIGFLRFYSLNDSRAFIE 234
                 579***********************99999987 PP

  == domain 2  score: 21.7 bits;  conditional E-value: 4.4e-08
                 SCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTE CS
       RRM_1  23 Gpiksiklvrd.etgkskgfafVeFeskedAekAlealngk 62 
                 G+ +++ lvrd + + s +f+f eF++ edA++Al +ln  
  EEA19420.1 385 GSLRRVLLVRDrRSNESWKFGFAEFATLEDAQAALVKLNSF 425
                 788999*********************************85 PP

  == domain 3  score: -3.9 bits;  conditional E-value: 4.3
                 SHHHHHHHHHHHTT CS
       RRM_1  48 skedAekAlealng 61 
                 ++e  +kAl++l +
  EEA19420.1 605 NEEMVTKALAKLEK 618
                 789999***99976 PP

>> G-patch_2  G-patch domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.7   0.2   8.3e-11   2.5e-07       2      59 ..     655     712 ..     652     714 .. 0.90

  Alignments for each domain:
  == domain 1  score: 30.7 bits;  conditional E-value: 8.3e-11
   G-patch_2   2 eeasleeyeevPVeeFGaAlLrGMGWkegqgigknkkgrvkpeepkrRpgrlGLGakp 59 
                 + ++ ee + +P  + GaAlL  MGW+eg g g +++g ++p+  +  +++ GLGa+ 
  EEA19420.1 655 TTQDIEEPATAPAPSKGAALLSKMGWSEGSGLGAQGTGMTTPIATDVYAQGVGLGAQG 712
                 4455569999999999****************************************86 PP

>> RED_N  RED-like protein N-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.1      0.66     2e+03      14      36 ..     492     514 ..     483     563 .. 0.67
   2 !   16.9   1.0   1.3e-06    0.0038       6      41 ..     610     645 ..     605     671 .. 0.80
   3 ?   -5.9   3.0         6   1.8e+04      10      32 ..     723     745 ..     717     747 .. 0.76

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.66
                 XXXXXXXXXXXXXXXXXXXXXXX CS
       RED_N  14 eekeeelaekYrDRAkERRegkn 36 
                 ++k e+++ k  D+Ak R+ ++ 
  EEA19420.1 492 KSKSESKSTKDGDKAKKRKAEAS 514
                 23333334444444444444433 PP

  == domain 2  score: 16.9 bits;  conditional E-value: 1.3e-06
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX...XX CS
       RED_N   6 yaklkkqeeekeeelaekYrDRAkERRegknadyek 41 
                 +++l+k e++k+++ +  YrDRAkERR+   +  ++
  EEA19420.1 610 TKALAKLEKHKNDQPTTEYRDRAKERRQAFGSSRQT 645
                 567788999999***************986654443 PP

  == domain 3  score: -5.9 bits;  conditional E-value: 6
                 XXXXXXXXXXXXXXXXXXXXXXX CS
       RED_N  10 kkqeeekeeelaekYrDRAkERR 32 
                 +++ + + +e  ek +D A+ER 
  EEA19420.1 723 ARNTRGRYDEFLEKTKDLARERY 745
                 556666778999999******95 PP

>> NCD3G  Nine Cysteines Domain of family 3 GPCR
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   2.2   0.00063       1.9      24      49 ..     273     297 ..     261     299 .. 0.82
   2 ?    2.9   0.2     0.037   1.1e+02      16      29 ..     568     580 ..     559     586 .. 0.74

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00063
       NCD3G  24 CCwdCvpCpegeistdseeCtkCped 49 
                   w+C++C+ +++    ++C +C+ d
  EEA19420.1 273 GEWTCRNCSFENFA-TRQKCFRCQAD 297
                 55**********99.8999****976 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.037
       NCD3G  16 kvqegepvCCwdCv 29 
                 +++ +++ CC+ C 
  EEA19420.1 568 YADLNRN-CCYLCM 580
                 4555555.*****7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (749 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1078  (0.0601261); expected 358.6 (0.02)
Passed bias filter:                      535  (0.0298399); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.67u 0.31s 00:00:00.98 Elapsed: 00:00:00.49
# Mc/sec: 4559.21
//
Query:       EEA19421.1  [L=582]
Description: oligo-1,6-glucosidase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
     4e-114  381.7   0.6   7.3e-114  380.8   0.6    1.3  1  Alpha-amylase    Alpha amylase, catalytic domain
    5.4e-08   32.8   0.1      1e-07   32.0   0.1    1.5  1  Malt_amylase_C   Maltogenic Amylase, C-terminal domain
     0.0049   16.0   0.0     0.0094   15.1   0.0    1.4  1  hDGE_amylase     Glycogen debranching enzyme, glucanotransfer
  ------ inclusion threshold ------
      0.016   15.7   0.1      0.042   14.3   0.1    1.8  1  Alpha-amylase_C  Alpha amylase, C-terminal all-beta domain


Domain annotation for each model (and alignments):
>> Alpha-amylase  Alpha amylase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  380.8   0.6  1.6e-117  7.3e-114       1     334 [.      32     388 ..      32     391 .. 0.97

  Alignments for each domain:
  == domain 1  score: 380.8 bits;  conditional E-value: 1.6e-117
                    --CHHHHCTCCCCCCCT-SCEEE-B-CE-S-TTTTSS-SCECCE-CCC--CCCCCCHHHHHHCTT-EEEEEE--SC--TTSCCCHCCHHSTTSGGG CS
  Alpha-amylase   1 GDLkGiiekLdYlkeLGvtaiwlsPifkspqadhgYdiadytkidpefGtnedlkeLiskahekgikvilDlVvNHtsdehewfkeslkkkgepkr 96 
                    GD+ Gii+kLdY+k+LGv+ iwlsP +kspq d+gYdi+dy++i+  +Gt +d+++Lis +h++g+k+++DlVvNHtsd hewf++s+++k+++ r
     EEA19421.1  32 GDIPGIISKLDYIKQLGVDIIWLSPSYKSPQVDMGYDISDYYSIHAPYGTVDDVEKLISGCHKRGMKLLMDLVVNHTSDRHEWFQKSRSSKDNEFR 127
                    9*********************************************************************************************** PP

                    CCC-E..........ESS-STTC-TTTTCSCEECTTTTCEEESSS-TTS-BB-TTTCCCCCCCCCCCCCCCTTT-SEEEETTCCCTTTCCCC.... CS
  Alpha-amylase  97 dyyiwkegk....eekeppnnwkslfdgsaweydekaqeyylhlflkklpdLnteneevrkelkdvvkfwlekgidGfRlDvvkhvskveal.... 184
                    d+yiwk+++    ++++ppnnw s+f+gsaw+yd+ ++eyylhl ++ +pdLn+e++ vrk+++d+v+fwl+kg dGfR+Dv++ +sk++++    
     EEA19421.1 128 DWYIWKPPRfdeqGNRHPPNNWVSHFQGSAWKYDDLTGEYYLHLYAEAQPDLNWEHPPVRKAVYDIVRFWLDKGCDGFRMDVINFISKNQEFpdgp 223
                    *******99999999*************************************************************************9999**** PP

                    ..............HCCHCCHHHHHHHHHHHTCCGTT-EEEEE-T.T-SCCCHCCCC-CGG-SICECCITTCGGGCC-CTSTTSB-SS-HHHHHHH CS
  Alpha-amylase 185 ..............esngeflheftqalnetvasrkevmtvgEvs.sdasedlrvyttearlelemvldfphldvaqkakikeqlksisakklkel 265
                                  + ng++lhe+ q++ +   ++++++ vgE+   ++ ed  + +  +r+e++m++df+h+dv+++  +k      ++ +lk l
     EEA19421.1 224 vtnpetpwqwghthYANGPRLHEYLQDIGKIL-QEYDAFSVGEMPfATTLEDVLKAVRFDRKEINMIFDFEHVDVDHGKLDKFGRGRWKLTDLKRL 318
                    **************9**************876.999********6155567888899999********************9*************** PP

                    HHHHHHHS-CCCTTCEEES--TTS--HHHHTTSSTTTT.HHHHHHHHHCCCTSSSEEEEETTCCCT---- CS
  Alpha-amylase 266 lkkwlkaleeaaeeavtflgnHDqeRilsrlgddsaea.ekklklaaillltlrGvpviYyGeEigmtgg 334
                    ++kw++ + e++ +++++++nHDq+R++ r+   s+e+ ++  k++a+ l ++ G+p++Y+G+E+gm ++
     EEA19421.1 319 FNKWQTFMYENQGWNALYWENHDQPRSIDRYTGASPEHsVIAGKMLATCLALMAGTPFVYQGQELGMRNV 388
                    ********************************9999999****************************997 PP

>> Malt_amylase_C  Maltogenic Amylase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.0   0.1   2.2e-11     1e-07       1      52 [.     501     553 ..     501     578 .. 0.79

  Alignments for each domain:
  == domain 1  score: 32.0 bits;  conditional E-value: 2.2e-11
                     -EEEE---S-TTEEEEEEEETTEEEEEEEESS-EEEEE--G.GGTT-EEEETT CS
  Malt_amylase_C   1 GsfefleadnrkvlaYlReyedetilvvaNrsaqaveldls.elagrvpvelf 52 
                     G+f +++ dn++++aY+R+ ++++ lvv+N++++  e+d   +l  ++++e++
      EEA19421.1 501 GDFVLVDRDNENIFAYTRQFGNQQALVVCNFTDRMIEWDSTkNLIRGEVKEVL 553
                     9***********************************99998855555555544 PP

>> hDGE_amylase  Glycogen debranching enzyme, glucanotransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   2.1e-06    0.0094      26     112 ..      39     117 ..      30     124 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 2.1e-06
                   HHHHHHHHTT--EEEES--EEE-TT--TTSEEEEEEE-TTT-.....SSC.HHHHHHHHHHHHHH--EEEEEE--SEEETT-CCCCC CS
  hDGE_amylase  26 kvlkeikekgYnmiHftPlqelGesnSpYSiadqleldkelfeekdkeekeedveklvkklekeygllsltDvVlnHtannskwlee 112
                   ++l+ ik+ g ++i ++P  +  + +  Y i+d  +++           +++dvekl++ ++k  g+  l+D+V nHt++  +w ++
    EEA19421.1  39 SKLDYIKQLGVDIIWLSPSYKSPQVDMGYDISDYYSIHAPY-------GTVDDVEKLISGCHK-RGMKLLMDLVVNHTSDRHEWFQK 117
                   57888999999999999999999999999999999998877.......4789********986.589999**************987 PP

>> Alpha-amylase_C  Alpha amylase, C-terminal all-beta domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.1   9.4e-06     0.042       6      33 ..     508     536 ..     503     570 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 9.4e-06
                      ETTSSEEEEEECTTT.EEEEEEE-SSSSE CS
  Alpha-amylase_C   6 deenkviaFeRgdge.kllvvfNfhpsns 33 
                       ++++++a+ R+ g+ ++lvv+Nf++   
       EEA19421.1 508 RDNENIFAYTRQFGNqQALVVCNFTDRMI 536
                      5689*******888889*******98654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (582 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       511  (0.0285013); expected 358.6 (0.02)
Passed bias filter:                      391  (0.0218082); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 4073.32
//
Query:       EEA19422.1  [L=64]
Description: hypothetical protein PMAA_002160 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (64 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       285  (0.015896); expected 358.6 (0.02)
Passed bias filter:                      259  (0.0144459); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.35u 0.24s 00:00:00.59 Elapsed: 00:00:00.39
# Mc/sec: 493.13
//
Query:       EEA19423.1  [L=498]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-05   24.4   0.1    0.00034   20.1   0.1    2.2  1  Fringe    Fringe-like
  ------ inclusion threshold ------
      0.016   15.1   0.4      0.031   14.2   0.4    1.4  1  PAN_4     PAN domain
      0.028   14.4   0.0      0.061   13.3   0.0    1.5  1  PAN_1     PAN domain
        8.6    5.7   9.3         15    5.0   9.3    1.4  1  CAP_N     Adenylate cyclase associated (CAP) N terminal


Domain annotation for each model (and alignments):
>> Fringe  Fringe-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   0.1   7.5e-08   0.00034      83     200 ..     225     326 ..     212     335 .. 0.83

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 7.5e-08
      Fringe  83 leskkkWfchvDDDnylnveaLlklLskynhtqdvylGkpsldrpieaterteenkkkkvkfwfatGGaGfclsralalklaP.wasggrfvstsekir 180
                 l+ + kW++ +  D+ +   +L++ Ls+ ++ + +ylG                   +     fa+GG Gf+ls++ +++++  +a++ + +++  + +
  EEA19423.1 225 LKPDVKWYVFMEADTHIVWANLVAWLSRLDPREPLYLGTET----------------QIGDVLFAHGGSGFILSQRAMRMVSKqYAKKAKEYNAYTNEE 307
                 56678*********************************642................2234699**********9988888555888888888888889 PP

      Fringe 181 lpdDctlGfiieelLgvslt 200
                    D++lG +++   gv+lt
  EEA19423.1 308 WAGDMVLGKVLKD-AGVDLT 326
                 9*********998.677766 PP

>> PAN_4  PAN domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.4   6.9e-06     0.031       9      37 ..     417     443 ..     410     459 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 6.9e-06
       PAN_4   9 angevladspeaCcaaCaadsnCnawvyv 37 
                 +   +l+ +  +C++ C+ad  C+ +++ 
  EEA19423.1 417 ED--MLVENVHDCRRICEADGLCRQYSFR 443
                 44..478999**************99996 PP

>> PAN_1  PAN domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   1.4e-05     0.061      11      55 ..     411     462 ..     409     473 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.4e-05
                 EESEEEEEEECSSHHHHHHHHHHSTTS--SEEEEETT.........TTEEEEEE CS
       PAN_1  11 lsgedkktitvdsaeeCaerCseekkfrCrsftfnns.........tkeCylks 55 
                 lsg+ ++ + v+++ +C++ C+ +    Cr ++f+ s         ++eC+ ++
  EEA19423.1 411 LSGDLVEDMLVENVHDCRRICEADGL--CRQYSFRWSedpdvegewKPECRTFE 462
                 677888889999*************9..*********99999999999998765 PP

>> CAP_N  Adenylate cyclase associated (CAP) N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   9.3    0.0032        15     202     268 ..      13      80 ..       8     134 .. 0.60

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0032
                 HHHHHHHHHHH.HHSTTS----TTSBE.......SSC--XXXXXXX....XXXXXXXX.....XXXXX CS
       CAP_N 202 qilkeLqaYvk.eyhttGltWnkkGkdaeealkaaaaaasaaaaggpppPpPpPppasvfeeesaaas 268
                 +i+  L  +v    +  G++W    k+++++  +  +++ +++ ++++pPpPp pp+++++ +++a+ 
  EEA19423.1  13 TIVAPLIGFVVlLQFLRGPQWFMVAKSPSQISPRGGTSPDQQQLQKQQPPPPPIPPKKLAAPTRQAQR 80 
                 555555555441457899***98899999998755555555555554444444444444433322222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (498 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       612  (0.0341346); expected 358.6 (0.02)
Passed bias filter:                      491  (0.0273858); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.58u 0.24s 00:00:00.82 Elapsed: 00:00:00.41
# Mc/sec: 3633.99
//
Query:       EEA19424.1  [L=402]
Description: phosphopantothenate-cysteine ligase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-14   53.8   0.0    5.3e-06   26.4   0.0    3.2  3  DFP       DNA / pantothenate metabolism flavoprotein


Domain annotation for each model (and alignments):
>> DFP  DNA / pantothenate metabolism flavoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.4   0.0   2.9e-10   5.3e-06       4      55 ..      39      92 ..      36     121 .. 0.85
   2 !    6.9   0.0   0.00028         5      76     110 ..     166     202 ..     149     233 .. 0.74
   3 !   17.0   0.0   2.3e-07    0.0041     102     172 ..     236     309 ..     206     319 .. 0.80

  Alignments for each domain:
  == domain 1  score: 26.4 bits;  conditional E-value: 2.9e-10
                -EEEEEES-EEEECCT..TEEEEE----HHHHHHHHHHHHTT-EEEEEE-S-SS CS
         DFP  4 kkvlvtaGpTrEaiDp..VRfisNrSSGkmGyalAeaaaarGaeVtlvsgpvsl 55
                + vlvt+G+T  ++ +  VRfi N S G+ G++ Ae++++ G  V + + + sl
  EEA19424.1 39 RVVLVTSGGTTVPLENqtVRFIDNFSAGTRGASSAEQFLENGYAVIFLHRQFSL 92
                679***********7444*****************************9998754 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.00028
                 HHHHHTT-SEEEE---S--EEE..S------------ CS
         DFP  76 veealkeadivimaAAvaDyrp..keaaeeKikkeee 110
                 +++ l ++ ++  aAAv+D+ +  ++ ae+Ki+ +e 
  EEA19424.1 166 IMKPLGANALFYLAAAVSDFFIprDRMAEHKIQSSEI 202
                 4555667788999******987567789999997544 PP

  == domain 3  score: 17.0 bits;  conditional E-value: 2.3e-07
                 ----------..----EEE---HHHHHHHC-S.S.-EEEEEEE-SS..-HHHHHHHHHHHTT-SEEEEEEGGGT CS
         DFP 102 eeKikkeeeeeeltleleknpdilaelaekkkkk.qllvGFaaete..ellenareklerkgldlivaNdvske 172
                  eK + e+ +++l ++l + p+ l++l +  +++ +++v F++et+   l+ +ar+ l+r    l++ N +s++
  EEA19424.1 236 PEKEEDEHRSKKLIIDLDPVPKFLHRLVDGWAPEgSYIVSFKLETDpaLLVYKARTSLQRYAHHLVIGNLLSTR 309
                 45556667778899*************7655554268********7668899*****************99875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (402 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       548  (0.030565); expected 358.6 (0.02)
Passed bias filter:                      477  (0.0266049); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2759.58
//
Query:       EEA19425.1  [L=292]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.8e-07   29.5   0.0    7.8e-07   28.8   0.0    1.4  1  Lipase_2       Lipase (class 2)
    0.00011   21.9   0.2    0.00016   21.3   0.2    1.2  1  DUF2974        Protein of unknown function (DUF2974)
    0.00015   21.1   0.0    0.00018   20.8   0.0    1.1  1  Hydrolase_4    Serine aminopeptidase, S33
     0.0017   19.0   0.1     0.0024   18.5   0.1    1.2  1  Abhydrolase_6  Alpha/beta hydrolase family
     0.0058   16.3   0.2      0.022   14.4   0.1    2.0  2  Abhydrolase_1  alpha/beta hydrolase fold
  ------ inclusion threshold ------
      0.012   15.1   0.2      0.029   13.9   0.2    1.6  1  DUF676         Putative serine esterase (DUF676)
      0.025   14.3   0.0      0.031   14.0   0.0    1.2  1  PGAP1          PGAP1-like protein
      0.046   13.6   0.0      0.063   13.2   0.0    1.3  1  BAAT_C         BAAT / Acyl-CoA thioester hydrolase C terminal
      0.061   13.1   0.0      0.074   12.9   0.0    1.1  1  Palm_thioest   Palmitoyl protein thioesterase
        0.1   12.2   0.0       0.15   11.7   0.0    1.2  1  FSH1           Serine hydrolase (FSH1)


Domain annotation for each model (and alignments):
>> Lipase_2  Lipase (class 2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.8   0.0   4.4e-10   7.8e-07       2     206 ..      52     260 ..      51     267 .. 0.69

  Alignments for each domain:
  == domain 1  score: 28.8 bits;  conditional E-value: 4.4e-10
    Lipase_2   2 ePviivhGnsdlaaeklskliqkflekgyteaelYattygdteestslerle.kCeyvkqlRklilaVlkyTgakkvdivahsmGvpiaRkailGg... 96 
                 +Pv+++h+ +      l+ l ++ +++g+    +Ya tyg++ +   +  l    +  k +   i+ V +  g  kvdiv+hs+G+ +a ++ +     
  EEA19425.1  52 NPVVMIHALTASREVDLNLLHKNMTSEGWC---VYAQTYGSPINPPLIGGLTeMTKSAKDIGAYIVEVAQKKGG-KVDIVGHSEGGVMALYVPMTQpkv 146
                 8********999999999999999999953...8********998887776658999*****************.***********9998887666666 PP

    Lipase_2  97 .kcvdtnedLgepltskvdtfvs..vaganaGlllcasadstlepiCnkkngln..CeSkfLqdiNakkkke.geavfsiwskadevigkaklvcgket 189
                    vd+  +Lg+ ++  +   +    ++ + Gll   +a   ++p+C + + +       +L   N++k    + ++++i+s++d ++  +    +++ 
  EEA19425.1 147 aAVVDHAIALGPAVHGAHYFGLTdfFQALPDGLLKLLEA--AVKPLCAACIDMEnnDGDIYLAFKNSSKIVPdNINATVIMSNYDTLVPINVSRVDEPN 243
                 445588888888887665433321134566676655442..2333333333333211345666666666555455666677777776666666666666 PP

    Lipase_2 190 slipgskgkkiydklth 206
                 +++   ++++  d+l+h
  EEA19425.1 244 VRNLIVQDFCPDDHLNH 260
                 66666666666666666 PP

>> DUF2974  Protein of unknown function (DUF2974)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.2   9.1e-08   0.00016      69     115 ..     107     152 ..      99     167 .. 0.79

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 9.1e-08
     DUF2974  69 esAlkYlnkileesegkiylgGhSkGGnlAvyaamnaeddlqerisk 115
                 ++  +Y+ +++++  gk+ ++GhS GG +A+y+ m+ ++++ + +++
  EEA19425.1 107 KDIGAYIVEVAQKKGGKVDIVGHSEGGVMALYVPMT-QPKVAAVVDH 152
                 55568*****************************99.5555555555 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8   0.0     1e-07   0.00018      25     125 ..      73     174 ..      51     214 .. 0.75

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 1e-07
  Hydrolase_4  25 eaLaaqGfavyalDhrGhGrsegkrghvpsfddyvdDlaafvekvkeehpelplfllGhSmGGliallyllrypd...kvaglilsaPalkikaklka 119
                  ++++ +G+ vya    G   +++  g ++++++  +D+ a++ +v++++++ ++ ++GhS GG++al +  ++p+    v+ +i  +Pa+  ++++ +
   EEA19425.1  73 KNMTSEGWCVYAQ-TYGSPINPPLIGGLTEMTKSAKDIGAYIVEVAQKKGG-KVDIVGHSEGGVMALYVPMTQPKvaaVVDHAIALGPAVHGAHYFGL 168
                  5666667777663.5677777788899999***********9888855555.599***********99997777766577799*******99998853 PP

  Hydrolase_4 120 ppllkl 125
                  + + ++
   EEA19425.1 169 TDFFQA 174
                  333333 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.1   1.4e-06    0.0024      35     114 ..      85     174 ..      54     209 .. 0.60

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 1.4e-06
                    TTSTS-GGCS..--HHH....CHHHHHHHCCTT...TTSEEEEEETCHHHHHHHHHHCC...........EEEEES-..----TTTS----TTHHH CS
  Abhydrolase_6  35 pGhGrsdppp..ldled....ladlaalldelaa.gggpvvlvGHSlGGalalaaapla.........lvvgvlldppptalpagllaaalellla 114
                      +G++  pp   +l++    + d+ a++ e+a+  gg+v +vGHS GG++al    ++         ++++++l p   a+  +    +  +++a
     EEA19425.1  85 QTYGSPINPPliGGLTEmtksAKDIGAYIVEVAQkKGGKVDIVGHSEGGVMALY---VPmtqpkvaavVDHAIALGP---AVHGAHYFGLTDFFQA 174
                    455645443344444444344688877777777779**************9999...66667887876666699999...4444443333333333 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.1   1.2e-05     0.022       1     102 [.      52     150 ..      52     174 .. 0.79
   2 ?   -1.3   0.0      0.78   1.4e+03     204     248 ..     217     252 ..     194     261 .. 0.66

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.2e-05
                    SEEEEE-STTTCGGGGTTGHHHHHHHHTTSEEEEEEETTSTTSSSTTTGB.CHHSHHHHHHHHH.HH..HHHCTTSSEEEEEETHHHHHHHHHHHH CS
  Abhydrolase_1   1 pvlvilhGlpgssdvwaerglapaLakdgfdvillDlrGvgySspapacinddygtasvaddld.ri..ldalgddkltlvGhSmGGmialayaae 93 
                    +++v++h+l++s +v  + +l ++   +g++v++    G++  +p +    ++++    a+d+  +i  +++ + +k+ +vGhS GG +al++   
     EEA19425.1  52 NPVVMIHALTASREVDLN-LLHKNMTSEGWCVYA-QTYGSPINPPLIGGL-TEMTK--SAKDIGaYIveVAQKKGGKVDIVGHSEGGVMALYVPMT 142
                    699999999999999999.555566666999997.456777776666654.67777..8999998999********************99998887 PP

                    HGGGEEEEE CS
  Abhydrolase_1  94 yperVkalv 102
                     p+ V+a+v
     EEA19425.1 143 QPK-VAAVV 150
                    644.66555 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.78
                    HHCTHHHHSEEEEEEETTCSSSCHHHHHHHHHCHTSEEEEEEETC CS
  Abhydrolase_1 204 lrelknvlaptlvisgtsDplvppkaledlaqllpkkrlvvisda 248
                    +++      ++ vi +++D lvp+++++  +   p++r ++++d 
     EEA19425.1 217 DNI------NATVIMSNYDTLVPINVSRVDE---PNVRNLIVQDF 252
                    333......7788888999999998887766...55555555555 PP

>> DUF676  Putative serine esterase (DUF676)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.2   1.6e-05     0.029       8      95 ..      54     138 ..      51     154 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.6e-05
      DUF676   8 vVlvHGlqgn.saDlelikeqlekikeklpeekieflmsen..nesktfkgidvlg...erlaeevlevvkkkkdknkkiSfvghSlGgliara 95 
                 vV++H l ++ + Dl+l+++++        e   +++   +  ++    +g+++++   + ++ +++ev++kk  k   + +vghS Gg++a +
  EEA19425.1  54 VVMIHALTASrEVDLNLLHKNMTS------EGWCVYAQTYGspINPPLIGGLTEMTksaKDIGAYIVEVAQKKGGK---VDIVGHSEGGVMALY 138
                 899999999988899999999988......2334443333301444567777777622157999999998877666...99*********9866 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   1.7e-05     0.031      86     128 ..     117     159 ..      98     227 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1.7e-05
       PGAP1  86 sekeptsviliGHSmGGivaraaltlknyikqsvntiltlasP 128
                 ++k+  +v ++GHS GG++a  + + +  ++  v+  + l+  
  EEA19425.1 117 AQKKGGKVDIVGHSEGGVMALYVPMTQPKVAAVVDHAIALGPA 159
                 4777889*************99988777788888888888754 PP

>> BAAT_C  BAAT / Acyl-CoA thioester hydrolase C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   3.5e-05     0.063      12      52 ..     112     152 ..     107     207 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 3.5e-05
                 HHHCSTTB--SSEEEEEETHHHHHHHHHHHHSSSEEEEEEE CS
      BAAT_C  12 yllrhpkvkkdkigllGiSkGgelalllasflkkisavvli 52 
                 y+ +  + k+ k+ ++G+S Gg +al++ ++ +k+ avv +
  EEA19425.1 112 YIVEVAQKKGGKVDIVGHSEGGVMALYVPMTQPKVAAVVDH 152
                 7777788899****************************965 PP

>> Palm_thioest  Palmitoyl protein thioesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   4.1e-05     0.074       1     109 [.      53     166 ..      53     232 .. 0.64

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 4.1e-05
  Palm_thioest   1 PvviwhGldsaesn..mqklaeliekligtyvknveigesea......edrkasffgnlndqveavckklelangfhaiGfSQGglflRaliercdd 89 
                   Pvv++h l+++  +  ++ l + + ++ g +v+  + g+  +       +++ ++ +++ + + +v++k  +  +++++G+S Gg+++  ++ ++++
    EEA19425.1  53 PVVMIHALTASR-EvdLNLLHKNMTSE-GWCVYAQTYGSPINppliggLTEMTKSAKDIGAYIVEVAQK--KGGKVDIVGHSEGGVMAL-YVPMTQP 144
                   899999993333.33677777777775.56666666555544444444455555555555555556666..6799**********9985.5555544 PP

  Palm_thioest  90 kkn..vrnlislggpqaGvfgl 109
                   k    v++ i lg    G  ++
    EEA19425.1 145 KVAavVDHAIALGPAVHGAHYF 166
                   4446899999999888887773 PP

>> FSH1  Serine hydrolase (FSH1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   8.6e-05      0.15      68     123 ..      75     143 ..      42     156 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 8.6e-05
        FSH1  68 eesraWfrkkde.............kneyegleesldavkdyikengpfdGiiGFSqGaalaallasll 123
                  +s +W+   ++             ++  ++ ++  ++++++ +++g  + i+G S+G+++a ++ +++
  EEA19425.1  75 MTSEGWCVYAQTygspinppligglTEMTKSAKDIGAYIVEVAQKKGGKVDIVGHSEGGVMALYVPMTQ 143
                 556666666666666666666666566666667777899999999*****************9987766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (292 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       377  (0.0210274); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 1974.40
//
Query:       EEA19426.1  [L=163]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      3e-10   39.9   0.0    5.3e-10   39.1   0.0    1.7  1  Rieske    Rieske [2Fe-2S] domain
    2.6e-06   27.3   0.0      4e-06   26.7   0.0    1.3  1  Rieske_2  Rieske-like [2Fe-2S] domain


Domain annotation for each model (and alignments):
>> Rieske  Rieske [2Fe-2S] domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.1   0.0   5.9e-14   5.3e-10      22      79 ..      65     130 ..      13     140 .. 0.81

  Alignments for each domain:
  == domain 1  score: 39.1 bits;  conditional E-value: 5.9e-14
                 TTEEEEEEE-TTS-EEEEESC-TTTT-BCGGSEE.E.......TT.EEE-TTT--EEE.TTSBEEE- CS
      Rieske  22 ggeplvvlrdedgevyAlsdvCtHrgaplsegki.d.......ekgvleCpcHgwayd.adGkvikg 79 
                 +++++++++  +g+++A++++C+H   pls+g++ d         + ++Cp H+w++d ++G++  g
  EEA19426.1  65 LKDQVLIFKY-RGKIHAIDHQCPHSSFPLSQGNLfDiedfgikLSTGITCPKHEWSFDiTSGQADRG 130
                 456799***6.******************886664345677765559***********999998665 PP

>> Rieske_2  Rieske-like [2Fe-2S] domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.7   0.0   4.5e-10     4e-06      23      99 ..      66     144 ..      43     147 .. 0.84

  Alignments for each domain:
  == domain 1  score: 26.7 bits;  conditional E-value: 4.5e-10
                 TEEEEEEE-TTS-EEEEESS-TTTSSSTCCCSEEEECTT.....CEEEE-TTT--EEETTT-BBSS-TTSB-BEE-EEESTS CS
    Rieske_2  23 gkqvalfrlekeevyAidnldpaseanvlsrGlvgdkkg.....elvvasPlykqkfdLktGecledeevslkvypvrvedg 99 
                 ++qv++f + +++++Aid ++p  ++ +ls+G + d ++     ++ +++P ++  fd+++G+  +  +++lkv++v+++d+
  EEA19426.1  66 KDQVLIFKY-RGKIHAIDHQCPH-SSFPLSQGNLFDIEDfgiklSTGITCPKHEWSFDITSGQA-DRGNYKLKVWEVQLRDQ 144
                 579*****9.9************.5*******988875522222567***************95.8899*********9975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (163 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       495  (0.0276089); expected 358.6 (0.02)
Passed bias filter:                      452  (0.0252106); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.41
# Mc/sec: 1194.87
//
Query:       EEA19427.1  [L=247]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.4e-10   40.7   0.0    9.4e-10   38.8   0.0    1.9  1  GST_N_3        Glutathione S-transferase, N-terminal domain
    3.4e-10   40.1   0.0    6.2e-10   39.2   0.0    1.5  1  GST_N_2        Glutathione S-transferase, N-terminal domain
    5.4e-06   26.3   0.0      2e-05   24.5   0.0    1.9  2  GST_C_2        Glutathione S-transferase, C-terminal domain
     0.0024   18.0   0.0     0.0084   16.3   0.0    1.9  1  GST_C_3        Glutathione S-transferase, C-terminal domain
     0.0061   16.9   0.0      0.025   14.9   0.0    2.0  1  GST_N          Glutathione S-transferase, N-terminal domain
  ------ inclusion threshold ------
      0.067   13.4   0.0       0.13   12.4   0.0    1.6  1  GST_C          Glutathione S-transferase, C-terminal domain
       0.12   13.0   0.0       0.21   12.2   0.0    1.4  1  GST_C_5        Glutathione S-transferase, C-terminal domain
       0.12   12.4   0.1        2.7    8.1   0.0    2.4  2  TFIIA_gamma_N  Transcription initiation factor IIA, gamma sub


Domain annotation for each model (and alignments):
>> GST_N_3  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.8   0.0   4.2e-13   9.4e-10       5      75 .]      21     104 ..      19     104 .. 0.74

  Alignments for each domain:
  == domain 1  score: 38.8 bits;  conditional E-value: 4.2e-13
                 TTSHHHHHHHHHHHHHT--EEEE---.....TTTTHHHHHHH-...........TT--SSEE..ETTS-EEESHHHHHHHHHHHH-GGG CS
     GST_N_3   5 paSpyarrvrlaLnekglpvevvevt.....pgehdeellakn...........plgkvPvL..eddgealtdSlaIidyLeelypgpp 75 
                  +Sp ++r+rl+Ln+k++p+++  ++     p+ +     +              +++vP++  +++++ ++dSl+I+++Le+ y++pp
  EEA19427.1  21 CFSPTVWRIRLMLNYKRIPYKTIFLEfpdiePTLK-----ELGltpgktttgsqSKYTVPAIkhVPTNRCIMDSLVIAQFLESIYSEPP 104
                 69*****************9975554323333333.....22222333345667********55567*******************987 PP

>> GST_N_2  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.2   0.0   2.8e-13   6.2e-10       1      69 [.      22      98 ..      22      99 .. 0.78

  Alignments for each domain:
  == domain 1  score: 39.2 bits;  conditional E-value: 2.8e-13
                S-HHHHHHHHHHHHCT--EEEEEE.......H...-TTSHHHHHHHHCTTTSSSEEE-.CTTEEEESHHHHHHHHHH CS
     GST_N_2  1 aCPwahRvlialalkglediisvv.......vlepkgfekseefprlnprgtVPvLwd.kdgqvineSseIlrylet 69
                ++P ++R++++l++k+++++++++        l + g +++ +      ++tVP++ + ++++ i++S++I+++le+
  EEA19427.1 22 FSPTVWRIRLMLNYKRIPYKTIFLefpdiepTLKELGLTPGKTTTGSQSKYTVPAIKHvPTNRCIMDSLVIAQFLES 98
                89*******************996332223334555556665555555778*******56***************97 PP

>> GST_C_2  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0         1   2.2e+03      37      50 ..      19      32 ..      19      52 .. 0.69
   2 !   24.5   0.0   8.8e-09     2e-05      14      63 ..     178     232 ..     155     245 .. 0.75

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 1
                HHHHHHHHHHHHHH CS
     GST_C_2 37 Dialapflvrlraa 50
                D+++ p+++r r  
  EEA19427.1 19 DACFSPTVWRIRLM 32
                89999999999765 PP

  == domain 2  score: 24.5 bits;  conditional E-value: 8.8e-09
                 CHHHCTTT---SS.....CTTCS--HHHHHHHHHHHHHHHHHHS----.TT-HHH CS
     GST_C_2  14 aldaleahLadsp....flfGdqptlaDialapflvrlraagpgfdir.eaypnl 63 
                  l a+ ++++       f++G++pt+aD++ a++l+ +r +++g   r  +yp+ 
  EEA19427.1 178 ELRAIGELMRTNKdegpFILGAKPTYADFFIAGTLQCARMVDEGVFQRfMKYPGY 232
                 55566666664334445************************99985555455543 PP

>> GST_C_3  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   3.8e-06    0.0084      37      83 ..     183     236 ..     130     240 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 3.8e-06
                 HHHHH.C.HGTSSSSTTS--HHHHHHHHHHHHHHHH.....TCCCC-HHHHHHH CS
     GST_C_3  37 ekvlk.k.kgggylvgdklTyADlalfqvldgleea.....ealkkfpklkaly 83 
                  +++  + ++g++++g k TyAD+++   l+  + +     +   k+p  k  y
  EEA19427.1 183 GELMRtNkDEGPFILGAKPTYADFFIAGTLQCARMVdegvfQRFMKYPGYKGIY 236
                 555555425666*************99999988887765433336666666555 PP

>> GST_N  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   1.1e-05     0.025      10      75 ..      22      97 ..      19      98 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.1e-05
                TSHTHHHHHHHHHHTT-EEEEEEECSTTTCGGCHHHHHHCTT...........S-SSEEEET..TEEEESHHHHHHHHH CS
       GST_N 10 gsprahrirlllaakgveyevvpldfeageekspellklnpl...........gkvPaLedn..gkkltESraIleYia 75
                 sp ++rirl+l +k ++y++++l+f   ++ +p l+ l                vPa  +   + +++ S +I+++++
  EEA19427.1 22 FSPTVWRIRLMLNYKRIPYKTIFLEF---PDIEPTLKELGLTpgktttgsqskYTVPAIKHVptNRCIMDSLVIAQFLE 97
                57889********************9...77778888877777778888887778999999999999999999999886 PP

>> GST_C  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0     6e-05      0.13      44      76 ..     192     226 ..     142     237 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 6e-05
                 TSSSSSTTSSCHHHHHHHHHHHHHHHHTTTTT..T CS
       GST_C  44 kqdylvGdkltlADialvpilnwlqrlglafg..q 76 
                    ++ G k+t+AD+ ++  l+++++++ ++    
  EEA19427.1 192 EGPFILGAKPTYADFFIAGTLQCARMVDEGVFqrF 226
                 456999********************998876454 PP

>> GST_C_5  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   9.5e-05      0.21      21      97 ..     162     237 ..     145     245 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 9.5e-05
                 HHCTT-HHHH.HHHHHHHHHHHHHHCCHTSSSSECCECC--HHHHHHHHHHHHHHHHCCCCCT--CCCT-HHHHHHHH CS
     GST_C_5  21 vrdplseekr.kelddnaayledllakhqgeGPyfldkelsmadvavvPflvrlkavlsyyaGydlfakaPrlkklae 97 
                 v dp +ee+   ++d +   + +l+  ++ eGP+ l+ + + ad  +   l +++    + + +  f+k+P  k+++e
  EEA19427.1 162 VLDPTKEEQDwLAIDPELRAIGELMRTNKDEGPFILGAKPTYADFFIAGTLQCARM--VDEGVFQRFMKYPGYKGIYE 237
                 6677665543257888889999*******************************985..56678888888888888887 PP

>> TFIIA_gamma_N  Transcription initiation factor IIA, gamma subunit, helical domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0      0.12   2.7e+02       7      18 ..     120     131 ..     120     132 .. 0.90
   2 ?    8.1   0.0    0.0012       2.7       6      25 ..     151     170 ..     145     180 .. 0.77

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.12
  TFIIA_gamma_N   7 rstlGtaLtdaL 18 
                    rs lG++L d++
     EEA19427.1 120 RSILGKTLSDSI 131
                    699*******86 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0012
  TFIIA_gamma_N   6 RrstlGtaLtdaLDeliqeg 25 
                    R+ ++G++L+d LD   +e+
     EEA19427.1 151 REASIGRSLEDVLDPTKEEQ 170
                    6667**********766655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (247 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       289  (0.0161191); expected 358.6 (0.02)
Passed bias filter:                      287  (0.0160076); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.43u 0.25s 00:00:00.68 Elapsed: 00:00:00.40
# Mc/sec: 1847.74
//
Query:       EEA19428.1  [L=647]
Description: hypothetical protein PMAA_002220 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.9e-58  196.6   0.3    1.3e-57  195.7   0.3    1.5  1  DDE_Tnp_1_7      Transposase IS4
    7.8e-12   45.8   9.4    1.7e-11   44.7   9.4    1.6  1  Tnp_zf-ribbon_2  DDE_Tnp_1-like zinc-ribbon


Domain annotation for each model (and alignments):
>> DDE_Tnp_1_7  Transposase IS4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  195.7   0.3   1.5e-61   1.3e-57       2     350 .]     125     538 ..     124     538 .. 0.90

  Alignments for each domain:
  == domain 1  score: 195.7 bits;  conditional E-value: 1.5e-61
  DDE_Tnp_1_7   2 pvelFelflpdkilerivkatNayakqk.........kkwleltaeElkaFlGllllmglvrlpsvedyWstkdfyg....npllseiMsreRFeeil 86 
                  p+++F+lf+++++++ +++ tN+ya  k         ++w+ +t  ElkaF+G+++ mg  + p+++dyW+++++ +    n++ls +++  RFe++ 
   EEA19428.1 125 PYQIFSLFFTEDLFKVLADNTNMYAYAKlsknmnphhRNWRSTTPGELKAFVGAQIYMGFTKEPQLKDYWDEEKHNKsvhaNHPLSNYITCFRFEQLK 222
                  9**********************************************************************9995555678***************** PP

  DDE_Tnp_1_7  87 salhladn........................stkkaekdklkkvrelidslnermqkvyrpsqtlvldeslvlfkgrvpfkqylpgkprkvgiklhv 160
                  + +h++++                        s+++ +    +kv  ++d l +  +++y ps+++++de +v  +gr +    +p+kp   g+k++v
   EEA19428.1 223 RFFHISEPsevpggfistyyrpepteeeelqlSEEQLSGIWWHKVHTVFDILRKASKNLYIPSSNISIDEAMVCSHGRSSHTYKMPNKPISQGFKIFV 320
                  ***********************9999888664444488999******************************************************** PP

  DDE_Tnp_1_7 161 lcdsqtgyilalelyegearnlrl..srelgktnalvlrLleplqgkg..rvvvmdnfftslellqeLakkgtyavGtlkknrsglPkeltqklpkge 254
                  l+d   gy + +++  ++++ ++    +el+kt ++v +L+++l + +  + +++dn+fts++l+++L++ ++ a+Gt +  ++++P+ l++ ++ g+
   EEA19428.1 321 LAD--HGYCYYFYPASRTKGVVEVgmAKELTKTGQMVYELVQTLPKDNktYDLYLDNYFTSVNLFKALREIQVGACGTTRP-HKEFPNLLKKLKDLGS 415
                  ***..9**********999877653378****************965555*******************************.77***88876666666 PP

  DDE_Tnp_1_7 255 llaryg......gplmllkwndrkkvkllstyss....qklveskersg................qki..karpklvedYnqalgavdrhdqllqayr 324
                     +++      +++  ++w d++ v+ l+t+++    ++ +e+ +r+                 q +     p  ++dYn ++g+vd ++q ++ y 
   EEA19428.1 416 YIPYHKvcaipvNDVLCVAWQDNNIVLALTTIHTvdqtDDYIERTRRRPqktstngplvhkefgeQAVknMPIPRFIDDYNSHMGGVDIANQHRAVYD 513
                  666666666666**********************876555588777775677888899999998844543479************************* PP

  DDE_Tnp_1_7 325 aslktskkwykrvlifllsiavvNAy 350
                   ++k+ ++w+  +   +l++ +vNAy
   EEA19428.1 514 THIKAFRSWWP-LWNWCLDVGIVNAY 538
                  **********9.*************9 PP

>> Tnp_zf-ribbon_2  DDE_Tnp_1-like zinc-ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.7   9.4   1.9e-15   1.7e-11       1      31 []     599     640 ..     599     647 .] 0.94

  Alignments for each domain:
  == domain 1  score: 44.7 bits;  conditional E-value: 1.9e-15
  Tnp_zf-ribbon_2   1 kRCkvClkkkikke.......TriiCqeCdvplCrnh....C 31 
                      kRC++Cl+k++k++       T++iCq+CdvplCr++    C
       EEA19428.1 599 KRCIWCLYKNPKRQtgqspsfTTFICQACDVPLCRPEtgrtC 640
                      8**********************************9877776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (647 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       592  (0.0330191); expected 358.6 (0.02)
Passed bias filter:                      481  (0.026828); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.27s 00:00:00.88 Elapsed: 00:00:00.41
# Mc/sec: 4681.29
//
Query:       EEA19429.1  [L=434]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    0.00033   20.0   0.0    0.00057   19.2   0.0    1.4  1  PNP_UDP_1  Phosphorylase superfamily
  ------ inclusion threshold ------
      0.042   14.2   0.0       0.17   12.3   0.0    1.9  2  AAA_16     AAA ATPase domain


Domain annotation for each model (and alignments):
>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   0.0   6.3e-08   0.00057     109     222 ..     232     337 ..     196     347 .. 0.73

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 6.3e-08
                 HHCCTCCCCTTSSEE--HHHHHHHHHCHHTTT...TTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTBE CS
   PNP_UDP_1 109 pkeegqyfpdsydapadpelrallkeaaealg...ikvhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArelgipfaairvvsdlaagg 204
                 ++++gq +  +y++  d++ +++l++  ++++   i+v +G++++++    + e +++l  +++  +++ Etaa  +    ++ip+++ir+v d +++ 
  EEA19429.1 232 FRDPGQDHDEVYEI--DEDGTECLVKREQRQDskrIRVWYGPIGSGEKLIQSAEKRNELRDKYN--IIGLETAAAGI---MNQIPVGVIRGVCD-YGD- 321
                 33334555555555..**********777777999******************99999999999..*******9776...589***********.444. PP

                 TTCTCH.HCCCHHHHHHH CS
   PNP_UDP_1 205 adaeatheeveefaqeaa 222
                   ++  +e +  +a+ aa
  EEA19429.1 322 --EHKKKEWQPYAAAMAA 337
                 ..3222222222222222 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0      0.27   2.4e+03      54      88 ..     311     350 ..     296     366 .. 0.67
   2 ?   12.3   0.0   1.9e-05      0.17       2      41 ..     380     419 ..     379     431 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.27
      AAA_16  54 iflrgkcdqlesa.....ipysa.laqalareellrqllde 88 
                  ++rg cd  ++       py+a  a a a+  +l q+  +
  EEA19429.1 311 GVIRGVCDYGDEHkkkewQPYAAaMAAAYAK-AVLYQISPK 350
                 5677777776333345668997756666645.777777655 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 1.9e-05
      AAA_16   2 lvGReeeleqLlsalervrsgrpelvllsGesGvGKsslv 41 
                 +  R +el+qL +  ++ +s + e+ +l+G  G+GK+ l+
  EEA19429.1 380 FLERYQELQQLWHHSKPGNSKSQEASVLHGIGGTGKTQLA 419
                 67789999999999999999999**************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (434 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       348  (0.0194099); expected 358.6 (0.02)
Passed bias filter:                      338  (0.0188521); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.47
# Mc/sec: 2785.96
//
Query:       EEA19430.1  [L=424]
Description: multidomain presynaptic cytomatrix related protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-26   91.1   1.3      5e-26   90.3   1.3    1.5  1  Atg29_N   Atg29 N-terminal domain
  ------ inclusion threshold ------
      0.014   15.0   0.0      0.021   14.4   0.0    1.3  1  Drf_GBD   Diaphanous GTPase-binding Domain


Domain annotation for each model (and alignments):
>> Atg29_N  Atg29 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.3   1.3   5.6e-30     5e-26       1      54 []      12      65 ..      12      65 .. 0.99

  Alignments for each domain:
  == domain 1  score: 90.3 bits;  conditional E-value: 5.6e-30
     Atg29_N  1 ytVfiRLPfpRgdFvDPPpveWdaekdeaLWkilskaskkkeiDWkelaeefev 54
                ytVf+RLPfpRgdF+DPPp +W+  kd+aLW+ils+ sk ++iDWk++a++f+v
  EEA19430.1 12 YTVFVRLPFPRGDFIDPPPANWNLVKDRALWEILSQPSKGNDIDWKAIADDFNV 65
                8***************************************************98 PP

>> Drf_GBD  Diaphanous GTPase-binding Domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   2.4e-06     0.021       5      54 ..     286     357 ..     282     422 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 2.4e-06
     Drf_GBD   5 deeeidklFeelleelnlpeekreallalpiekKwqlvvqdkkkkakke......................e 54 
                 +e  ++++   l ++ n+pe  r++++ + ++++++lv  d+++++                          
  EEA19430.1 286 NEVNVQHMNSTLRQQNNIPETSRRQMAGYTPSHRRELVSLDSSASSGVAigspragpqrsteplsprrvanL 357
                 4556667766777777**************************988877766666666666655555555551 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (424 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       846  (0.0471861); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.24s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 2880.43
//
Query:       EEA19431.1  [L=233]
Description: hypothetical protein PMAA_002250 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.6e-06   26.5   0.0    7.6e-05   22.7   0.0    2.0  2  APH             Phosphotransferase enzyme family
  ------ inclusion threshold ------
      0.051   13.2   0.0      0.081   12.5   0.0    1.3  1  Choline_kinase  Choline/ethanolamine kinase
      0.075   12.7   0.0       0.13   11.9   0.0    1.4  1  TMEM71          TMEM71 protein family


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0     0.035   2.1e+02      21      90 ..      39     104 ..      24     121 .. 0.75
   2 !   22.7   0.0   1.3e-08   7.6e-05     172     229 ..     130     184 ..     124     193 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.035
                 --EEEEEE-TTS-HHHHHHHHHHHHHHHHTT-B--B-CTTBS-EEETTEEEEEEE----EE-SS.HHHHHH CS
         APH  21 gryvlrrnpparaaeeirrevallrlLakagvpvPevlagdtddeeigllfalieyvpgrsllr.klsaaq 90 
                  ++v+++ +   +  e+ ++++++  +    v+vP v+ +    +++g+ + +  ++ g+++++ +  +++
  EEA19431.1  39 YDLVVKFGRQV-SSYEAKNQQKEYNIVDPKIVTVPWVHNFF--VDDEGWGYMVSDFIAGKTIDPlP--HSH 104
                 46788888888.88888899999999998867999999874..55666679999999999999942..333 PP

  == domain 2  score: 22.7 bits;  conditional E-value: 1.3e-08
                 S-SGGGEEEC..TTEEEEE---TT-EEEECCHHHHCCHHHCSCHCCCHCHHHHHHHHC CS
         APH 172 DlhpgNllvdpddgrvtGviDfedaglgpplyDlavllrswtseldpeflaallraye 229
                 D+ p+Nl++  d+gr+ +++D+e ag  p+  ++a+l  +   ++++ +l a++ + e
  EEA19431.1 130 DITPRNLIWL-DGGRI-CLLDWESAGFYPRQLEFASLF-YQEYHFGDVLLSAIGFGSE 184
                 899*******.99**9.********************9.4345577777776666555 PP

>> Choline_kinase  Choline/ethanolamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   1.4e-05     0.081     145     188 ..     124     166 ..     101     177 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.4e-05
                     EEEE-S--SGGGEEE.-CTTEEEE--GTT-EEEEHHHHHHHHHH CS
  Choline_kinase 145 vvfcHnDlqegNillnkeekklvlIDFEYagynyrgfDlanhfi 188
                       f   D+ ++N++   + ++++l D+E ag+ +r  ++a  f 
      EEA19431.1 124 RLFPRDDITPRNLIW-LDGGRICLLDWESAGFYPRQLEFASLFY 166
                     5667779*******9.999*********************9985 PP

>> TMEM71  TMEM71 protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   2.2e-05      0.13     115     150 .]     106     141 ..     102     141 .. 0.93

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 2.2e-05
      TMEM71 115 rslsslldlsasksWlegsifgdvdsspsedswleg 150
                 + l+s+ld+++ + W+++++f + d +p++ +wl+g
  EEA19431.1 106 QKLASVLDVEQVEEWFNSRLFPRDDITPRNLIWLDG 141
                 569******************************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (233 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       435  (0.0242624); expected 358.6 (0.02)
Passed bias filter:                      408  (0.0227564); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.42u 0.25s 00:00:00.67 Elapsed: 00:00:00.42
# Mc/sec: 1670.01
//
Query:       EEA19432.1  [L=108]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.1e-26   90.8   0.5    8.4e-26   90.6   0.5    1.0  1  Dak1      Dak1 domain


Domain annotation for each model (and alignments):
>> Dak1  Dak1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.6   0.5   4.7e-30   8.4e-26       5      82 ..      27     104 ..      23     106 .. 0.93

  Alignments for each domain:
  == domain 1  score: 90.6 bits;  conditional E-value: 4.7e-30
                 HH-TTEEEETTTTEEEETT-S-TTS-EEEEEEEESSTTTTGGGBSBTSBSEEEEEEETS---HHHHHHHHHHH--SS- CS
        Dak1   5 aanpelklleeekvvvrkkekkkgkValisgGGSGHePahagfVGkgmldaavaGevFaSPsakqilaaikavdsgkG 82 
                 ++ + l++l++e+v++r+  + ++kV l+sgGGSGH Pah+g+VG+gmld +vaG++FaSPsa+qila +++vd+++G
  EEA19432.1  27 RSAEGLRVLPKEQVLYRQLPEGHRKVILLSGGGSGHGPAHTGYVGDGMLDVVVAGNIFASPSASQILAGVQSVDAPQG 104
                 445559***********99999****************************************************9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (108 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       199  (0.0110993); expected 358.6 (0.02)
Passed bias filter:                      177  (0.00987227); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.22s 00:00:00.62 Elapsed: 00:00:00.40
# Mc/sec: 814.06
//
Query:       EEA19433.1  [L=1718]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.4e-11   41.8   0.0    1.6e-10   41.0   0.0    1.3  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    1.6e-07   31.5   0.3    5.7e-06   26.5   0.0    2.9  3  rve              Integrase core domain
    0.00023   21.0   0.2    0.00075   19.3   0.2    1.8  1  gag_pre-integrs  GAG-pre-integrase domain
  ------ inclusion threshold ------
       0.14   12.4   0.0       0.75   10.0   0.0    2.3  2  PAC4             Proteasome assembly chaperone 4
       0.85    9.8   8.7       0.47   10.6   0.1    3.6  3  Integrase_H2C2   Integrase zinc binding domain


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.0   0.0   4.6e-14   1.6e-10       7     178 ..    1209    1384 ..    1205    1441 .. 0.81

  Alignments for each domain:
  == domain 1  score: 41.0 bits;  conditional E-value: 4.6e-14
       RVT_2    7 slPkdrkaigsrWvftkkkddlkevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeee.lvvhqldvdsafLnae..ldeevyvkqP 100 
                  + P + +  g r+v   k++  +++  k+rlv+q ++ k ++++  + +P i+ +s rL+l + + ++ +  +  dv  a+++++  l+ e y++ P
  EEA19433.1 1209 DIPLEARIYGFRFVDEVKNKGTDKAFEKSRLVVQAYNDK-DKEFVLTQSPTIQRSSQRLILCIGTSKDgVRFWIRDVTQAYIQSTtkLNREFYIRIP 1304
                  568889999*********9999**************987.567999*****************876651556677*******987336788****** PP

       RVT_2  101 pGfeidreeekvykLnkslyGlkqapllWnekidk.vLkklgferseaesGly.vrgtgegklivalyvddlliagsdik 178 
                  p         +  ++ + lyG+  a+  W+++ ++   ++lg+e s+    l  +    +g  ++++  dd li++++  
  EEA19433.1 1305 PELRHYFPGCEFLRVVRPLYGIPEAGNHWFRTYHEhHTTHLGMETSTYDPCLLhCCDPKQGFGVIGMQTDDTLIVADEAF 1384
                  ****99888999*****************99886615678899999998876515555666689**********998764 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0       2.4   8.6e+03      71      98 ..     499     530 ..     495     533 .. 0.80
   2 ?    1.4   0.0     0.094   3.4e+02      30      91 ..     758     825 ..     754     830 .. 0.76
   3 !   26.5   0.0   1.6e-09   5.7e-06       7     117 ..     847     950 ..     842     952 .. 0.78

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 2.4
         rve  71 lsDngseytsk....afrefladlgirvsftr 98 
                 ++D  ++ +      a+ +f++++  ++++ r
  EEA19433.1 499 HTDEERTAARArykpAWDKFIQQYEGTPDMER 530
                 6777776664478899********99998877 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.094
         rve  30 vddfsrlilaealsdemdastvlalleravarfggve.......pervlsDngseytskafrefladlg 91 
                 + d+s + ++ +  de++  +++  l+r  +rfg+          +r  +D  +e++ +++ +f+++ +
  EEA19433.1 758 IWDYSLMSYITQSFDEDQCFLTATELRRLHRRFGHPSvgrlhktLLRAGYDTNPEMI-EKINRFCHHCQ 825
                 679999**********55555555555555566655599999888889999999999.88888888865 PP

  == domain 3  score: 26.5 bits;  conditional E-value: 1.6e-09
         rve   7 lwqvDvtvvripdgggkayllvvvddfsrlilaealsdem..dastvlalleravarfggvepervlsDngseytskafrefladlgirvsftrpgrpq 103
                  + vD+++++    g  + +l++vd ++r+  a+ l + +  ++ ++l++l+  ++ + g  p+ +++D g+ ++sk+f+ ++++lg+     ++   +
  EEA19433.1 847 SIIVDIMYIN----G--KPVLHIVDEATRFNAACWLISISarATWDALRMLW--IDTYLGP-PDFIVTDAGKNFVSKEFTHLASSLGTITVSVPVEAHW 936
                 5667888888....3..5688999**99997666555552004444444444..6666666.**************************999999999** PP

         rve 104 dnGkvErfhrtlkd 117
                 + G vEr h  l++
  EEA19433.1 937 SIGAVERYHAVLRR 950
                 *********99987 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.2   2.1e-07   0.00075      22      63 ..     781     825 ..     765     826 .. 0.76

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 2.1e-07
  gag_pre-integrs  22 ssinlWHrRLGHpsfsrlkkLfkkgllpglki..sk.sevCeaCq 63 
                      +++++ HrR+GHps++rl+k   +   + +++  +k +++C++Cq
       EEA19433.1 781 TELRRLHRRFGHPSVGRLHKTLLRAGYDTNPEmiEKiNRFCHHCQ 825
                      678899************9988544444444333555889****9 PP

>> PAC4  Proteasome assembly chaperone 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0       4.7   1.7e+04      27      42 ..     365     380 ..     347     392 .. 0.66
   2 ?   10.0   0.0   0.00021      0.75      32      70 ..     544     584 ..     521     587 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 4.7
        PAC4  27 plgslvvAmpsrtnkk 42 
                 +l++l +++p+  + +
  EEA19433.1 365 KLQDLFYCLPDELQTQ 380
                 5799999999988733 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00021
        PAC4  32 vvAmpsrtnkktptisTtLlgdg.sde..aserlAqrLArRl 70 
                  +++p+rt+ + pt++T  ++   +d   +s++lA+ LA R 
  EEA19433.1 544 QYSLPDRTK-NEPTTATGYFTVAaTDHneFSSSLASELANRS 584
                 69******9.7799999999777553355**********995 PP

>> Integrase_H2C2  Integrase zinc binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.1       0.1   3.7e+02      25      42 ..     294     311 ..     292     313 .. 0.86
   2 ?   10.6   0.1   0.00013      0.47      10      53 ..     783     828 ..     778     831 .. 0.89
   3 ?   -0.1   1.0      0.29     1e+03      10      23 ..    1334    1348 ..    1328    1352 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.1
  Integrase_H2C2  25 tlerlrrryyWpgmrkdv 42 
                     +l+ ++  yyW ++++ +
      EEA19433.1 294 MLKDVALSYYWDNIDQWI 311
                     7889999*******9977 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00013
  Integrase_H2C2  10 lkeaHdsagHlGiektlerlrrryy..WpgmrkdvkkyvksCetCq 53 
                     l+++H   gH+++ +  ++l r  y   p m +++++++++C+t  
      EEA19433.1 783 LRRLHRRFGHPSVGRLHKTLLRAGYdtNPEMIEKINRFCHHCQTYG 828
                     899****************99999866799************9875 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.29
  Integrase_H2C2   10 lkeaHds.agHlGie 23  
                      ++ +H++ + HlG+e
      EEA19433.1 1334 FRTYHEHhTTHLGME 1348
                      799**********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1718 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       684  (0.0381505); expected 358.6 (0.02)
Passed bias filter:                      523  (0.0291706); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.93u 0.27s 00:00:01.20 Elapsed: 00:00:00.43
# Mc/sec: 11929.93
//
Query:       EEA19434.1  [L=1425]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.2e-11   42.2   0.0    1.3e-10   41.4   0.0    1.3  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    9.4e-08   32.3   0.3    4.5e-06   26.8   0.0    3.0  3  rve              Integrase core domain
    0.00017   21.4   0.2     0.0006   19.6   0.2    1.9  1  gag_pre-integrs  GAG-pre-integrase domain
  ------ inclusion threshold ------
       0.12   12.6   0.0       0.61   10.3   0.0    2.2  2  PAC4             Proteasome assembly chaperone 4
        1.5    9.0   9.6       0.38   10.9   0.1    3.7  3  Integrase_H2C2   Integrase zinc binding domain


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.4   0.0   3.5e-14   1.3e-10       7     178 ..     916    1091 ..     912    1148 .. 0.80

  Alignments for each domain:
  == domain 1  score: 41.4 bits;  conditional E-value: 3.5e-14
       RVT_2    7 slPkdrkaigsrWvftkkkddlkevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeee.lvvhqldvdsafLnae..ldeevyvkqP 100 
                  + P + +  g r+v   k++  +++  k+rlv+q ++ k ++++  + +P i+ +s rL+l + + ++ +  +  dv  a+++++  l+ e y++ P
  EEA19434.1  916 DIPLEARIYGFRFVDEVKNKGTDKAFEKSRLVVQAYNDK-DKEFVLTQSPTIQRSSQRLILCIGTSKDgVRFWIRDVTQAYIQSTtkLNREFYIRIP 1011
                  568889999*********9999**************987.567999*****************876651556677*******987336788****** PP

       RVT_2  101 pGfeidreeekvykLnkslyGlkqapllWnekidk.vLkklgferseaesGly.vrgtgegklivalyvddlliagsdik 178 
                  p         +  ++ + lyG+  a+  W+++ ++   ++lg+e s+    l  +    +g  ++++  dd li++++  
  EEA19434.1 1012 PELRHYFPGCEFLRVVRPLYGIPEAGNHWFRTYHEhHTTHLGMETSTYDPCLLhCCDPKQGFGVIGMQTDDTLIVADEAF 1091
                  ****99888999*****************99886615678899999998876515555666689**********998764 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       1.8   6.3e+03      71      98 ..     206     237 ..     200     241 .. 0.80
   2 ?    1.7   0.0     0.076   2.7e+02      30      91 ..     465     532 ..     461     537 .. 0.76
   3 !   26.8   0.0   1.3e-09   4.5e-06       7     117 ..     554     657 ..     549     659 .. 0.78

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1.8
         rve  71 lsDngseytsk....afrefladlgirvsftr 98 
                 ++D  ++ +      a+ +f++++  ++++ r
  EEA19434.1 206 HTDEERTAARArykpAWDKFIQQYEGTPDMER 237
                 6777776664478899********99999877 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.076
         rve  30 vddfsrlilaealsdemdastvlalleravarfggve.......pervlsDngseytskafrefladlg 91 
                 + d+s + ++ +  de++  +++  l+r  +rfg+          +r  +D  +e++ +++ +f+++ +
  EEA19434.1 465 IWDYSLMSYITQSFDEDQCFLTATELRRLHRRFGHPSvgrlhktLLRAGYDTNPEMI-EKINRFCHHCQ 532
                 679999**********55555555555555566655599999888899999999999.88888888865 PP

  == domain 3  score: 26.8 bits;  conditional E-value: 1.3e-09
         rve   7 lwqvDvtvvripdgggkayllvvvddfsrlilaealsdem..dastvlalleravarfggvepervlsDngseytskafrefladlgirvsftrpgrpq 103
                  + vD+++++    g  + +l++vd ++r+  a+ l + +  ++ ++l++l+  ++ + g  p+ +++D g+ ++sk+f+ ++++lg+     ++   +
  EEA19434.1 554 SIIVDIMYIN----G--KPVLHIVDEATRFNAACWLISISarATWDALRMLW--IDTYLGP-PDFIVTDAGKNFVSKEFTHLASSLGTITVSVPVEAHW 643
                 5667888888....3..5688999**99997666555552004444444444..6666666.**************************999999999** PP

         rve 104 dnGkvErfhrtlkd 117
                 + G vEr h  l++
  EEA19434.1 644 SIGAVERYHAVLRR 657
                 *********99987 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.2   1.7e-07    0.0006      22      63 ..     488     532 ..     472     533 .. 0.76

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 1.7e-07
  gag_pre-integrs  22 ssinlWHrRLGHpsfsrlkkLfkkgllpglki..sk.sevCeaCq 63 
                      +++++ HrR+GHps++rl+k   +   + +++  +k +++C++Cq
       EEA19434.1 488 TELRRLHRRFGHPSVGRLHKTLLRAGYDTNPEmiEKiNRFCHHCQ 532
                      678899************9988544444444333555889****9 PP

>> PAC4  Proteasome assembly chaperone 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       3.2   1.1e+04      27      42 ..      72      87 ..      53     100 .. 0.65
   2 ?   10.3   0.0   0.00017      0.61      32      70 ..     251     291 ..     228     294 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 3.2
        PAC4 27 plgslvvAmpsrtnkk 42
                +l++l +++p+  + +
  EEA19434.1 72 KLQDLFYCLPDELQTQ 87
                579999***9988733 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00017
        PAC4  32 vvAmpsrtnkktptisTtLlgdg.sde..aserlAqrLArRl 70 
                  +++p+rt+ + pt++T  ++   +d   +s++lA+ LA R 
  EEA19434.1 251 QYSLPDRTK-NEPTTATGYFTVAaTDHneFSSSLASELANRS 291
                 69******9.7799999999777553355**********995 PP

>> Integrase_H2C2  Integrase zinc binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.2      0.16   5.6e+02      25      42 ..       1      18 [.       1      20 [. 0.83
   2 ?   10.9   0.1   0.00011      0.38      10      53 ..     490     535 ..     485     538 .. 0.89
   3 ?    0.2   1.0      0.24   8.5e+02      10      23 ..    1041    1055 ..    1035    1059 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.16
  Integrase_H2C2 25 tlerlrrryyWpgmrkdv 42
                    +l+ ++  yyW ++++ +
      EEA19434.1  1 MLKDVALSYYWDNIDQWI 18
                    67788899******9977 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00011
  Integrase_H2C2  10 lkeaHdsagHlGiektlerlrrryy..WpgmrkdvkkyvksCetCq 53 
                     l+++H   gH+++ +  ++l r  y   p m +++++++++C+t  
      EEA19434.1 490 LRRLHRRFGHPSVGRLHKTLLRAGYdtNPEMIEKINRFCHHCQTYG 535
                     899****************99999866799************9875 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.24
  Integrase_H2C2   10 lkeaHds.agHlGie 23  
                      ++ +H++ + HlG+e
      EEA19434.1 1041 FRTYHEHhTTHLGME 1055
                      799**********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1425 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       470  (0.0262145); expected 358.6 (0.02)
Passed bias filter:                      360  (0.0200792); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.83u 0.28s 00:00:01.10 Elapsed: 00:00:00.46
# Mc/sec: 9370.40
//
Query:       EEA19435.1  [L=457]
Description: dihydroxyacetone kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-75  254.5   0.0    5.7e-75  252.1   0.0    1.9  2  Dak1      Dak1 domain
    4.6e-36  124.3   0.1    1.1e-35  123.1   0.1    1.6  1  Dak2      DAK2 domain
     0.0018   17.9   0.1     0.0044   16.6   0.0    1.7  2  Spo0M     SpoOM protein
     0.0044   17.0   0.2     0.0095   15.9   0.2    1.5  1  FR47      FR47-like protein


Domain annotation for each model (and alignments):
>> Dak1  Dak1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  252.1   0.0   1.3e-78   5.7e-75      85     310 ..       1     228 [.       1     229 [. 0.96
   2 ?    0.0   0.0      0.07   3.1e+02     243     272 ..     338     367 ..     310     381 .. 0.81

  Alignments for each domain:
  == domain 1  score: 252.1 bits;  conditional E-value: 1.3e-78
                 EEEESSHHHHHHHHHHHHHHHHTT--EEEEEE--B-SSSSSTTCSSSB--THHHHHHHHHHHHHHHT--HHHHHHHHHHHHTTEEEEEEEEE--B-TTT CS
        Dak1  85 livkNYtGDvlnfglAaekakaegikvetvvvdDDvavedseekagrRGvagtvlveKiaGaaAeegasLeevaelaekvaenlrsigvalsactvpga 183
                 +ivkNYtGD+lnfglAa ka+a+g++ve+vvv+DDv+v +++ ++grRG+ag v+v+K+aGa+A++ga+L+ v+++a+k+a+++++ +v+l++c+vp++
  EEA19435.1   1 MIVKNYTGDKLNFGLAAIKARASGLNVEVVVVGDDVSV-ANNPTVGRRGLAGVVFVHKVAGALAAKGADLSIVTNVANKTANQIATAAVSLDRCSVPKR 98 
                 69************************************.6889******************************************************99 PP

                 SSBSS---TTEEEETE-TTS---SEEEE---HHHHHHHHHHHHHH.........TT-EEEEEEEE-BSS-HHHHHHHHHHHHHHHHHTT-EEEEEEEES CS
        Dak1 184 gkpsfelaedeielGlGiHgEpGvervklksadelveelleklledke....lkkgdevvllvNglGgtsllelyivarevaelleekgikvvrvlvGe 278
                 + p + l+ de+e+G+GiH+EpGv+r+kl+s++ +v++ll+ ll++k+     ++ + v+++vN+lGg+s le++++a+ev+++l+ ++i v+r + G+
  EEA19435.1  99 A-PIEPLPFDEVEFGMGIHNEPGVTRSKLQSVEVTVSTLLDILLASKPdswyPSQAQPVAVMVNNLGGLSPLEISVIAEEVHRQLDLRSIIVKRFMFGT 196
                 9.7778**************************************8444577766699****************************************** PP

                 SS--TTBEEEEEEEEEE-HHHHHHHHS-EESS CS
        Dak1 279 yvTsldmaGfsitllklddellelldapvetp 310
                 +vT+ld++Gfsitll ldde+l+lldap+++p
  EEA19435.1 197 FVTALDGPGFSITLLGLDDEILSLLDAPTTAP 228
                 ****************************9986 PP

  == domain 2  score: 0.0 bits;  conditional E-value: 0.07
                 EE-BSS-HHHHHHHHHHHHHHHHHTT-EEE CS
        Dak1 243 NglGgtsllelyivarevaelleekgikvv 272
                   +Ggts     i++++vae+le+  i+ +
  EEA19435.1 338 TKMGGTSGAIYAIFINAVAEALENIHIHAT 367
                 579*******************98877654 PP

>> Dak2  DAK2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.1   0.1   2.5e-39   1.1e-35       2     155 ..     295     451 ..     294     454 .. 0.88

  Alignments for each domain:
  == domain 1  score: 123.1 bits;  conditional E-value: 2.5e-39
                 TS-S-HHHHHHHHHHHHHHHHHC-..--SSHHHHHHHHHHHHHHH--STHHHHHHHHHHHHHHHC...............TT---HHHHHHHHHHHHHH CS
        Dak2   2 vGDGDtGtnmargaeavlkaleel..eeaslaevlkalakallsgagGtsGvlysqflralakal......kekee....ldaedlaaalkaaleaiqa 88 
                 +GDGD+G+++ +g++ +++  ++l  ++  la++++++a ++++++gGtsG++y++f++a+a+al      +   +      ++ l++al+++le + +
  EEA19435.1 295 AGDGDCGETLLNGINGLIELSKRLdtNSIYLAHMFRQIAVVAETKMGGTSGAIYAIFINAVAEALenihihA---TsnkqSISKILSTALRKGLEDLFK 390
                 7******************9999966666789*********************************5555541...033323445599999********* PP

                 HH---TTSSSTHHHHHHHHHHHHT............T---HHHHHHHHHHCCS---SSGGGGGGGGGT CS
        Dak2  89 vgkarpgdkTmlDvlrpavealek.akdgedlkealekaakaaekgaeaTkellaklgrAsylgersl 155
                  + ar g++T++Dvl+p+v+++++ ++d       +e a +aa++g+e+Tk ++a lgrAsy+g++ +
  EEA19435.1 391 FTTAREGHRTLMDVLIPFVTTFNQtNQD-------FEVAFEAAKQGCEKTKVMEALLGRASYVGKSRF 451
                 ************************4444.......*****************************9865 PP

>> Spo0M  SpoOM protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   9.7e-07    0.0044      34     124 ..      53     146 ..      35     178 .. 0.85
   2 ?   -2.2   0.0      0.56   2.5e+03     153     194 ..     368     409 ..     352     429 .. 0.45

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 9.7e-07
                 EEEE--SS-EEEEEEEEEEEEEEEEEETTEEEEEEEEEEEEEEE--EEE-TT-EEEEEEEEE--TT----...-TT--EEEEEEEEESSS--EE CS
       Spo0M  34 vevkGGsveqeieeieleLvtrvekeeddkeveetvelarvrvaeaftiepgeereipfelelpletPit...lggakvwleTeldiagavDpg 124
                 v v+  + + + +  +l++vt+v +++ ++  ++ v+l+r++v ++  iep    e++f + ++ e  +t   l++++v+++T ldi  a  p+
  EEA19435.1  53 VFVHKVAGALAAKGADLSIVTNVANKTANQIATAAVSLDRCSVPKRAPIEPLPFDEVEFGMGIHNEPGVTrskLQSVEVTVSTLLDILLASKPD 146
                 55555555555667799*****************************************************999999***********9887665 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.56
                 EEEEEE-G.GG--.SSSEEEEEEEEESHHHHHH-S-EEEEEE CS
       Spo0M 153 sadleegklrgagqelpfvQelefvPsgeyagrldelEvvfl 194
                 s +   +k+  +  +  +   ++f+ ++e +++l ++ + f+
  EEA19435.1 368 SNKQSISKILSTALRKGLEDLFKFTTAREGHRTLMDVLIPFV 409
                 333333333333333444444555555555555555554443 PP

>> FR47  FR47-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.2   2.1e-06    0.0095      27      70 ..      38      82 ..      32      85 .. 0.89

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 2.1e-06
                EEE-GGG-SSSHHHHH.HHHHHHHHHHS-S-EEEEEETT-HHHHH CS
        FR47 27 lqvlpehrrrGlgsrl.vkalakeiaergktvllvvvasNtpsir 70
                +  +p++ rrGl++++ v+++a ++a++g ++++v++ +N+++ +
  EEA19435.1 38 VANNPTVGRRGLAGVVfVHKVAGALAAKGADLSIVTNVANKTANQ 82
                5567999*****987669***********************9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (457 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       476  (0.0265492); expected 358.6 (0.02)
Passed bias filter:                      388  (0.0216409); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.42
# Mc/sec: 3254.40
//
Query:       EEA19436.1  [L=722]
Description: dihydroxy-acetone synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.1e-127  425.6   0.1   1.6e-127  425.1   0.1    1.2  1  Transketolase_N  Transketolase, thiamine diphosphate binding 
    1.9e-37  128.7   0.0    5.1e-37  127.3   0.0    1.6  1  Transket_pyr     Transketolase, pyrimidine binding domain
    7.4e-07   29.1   0.0    1.8e-06   27.8   0.0    1.7  1  Transketolase_C  Transketolase, C-terminal domain
    3.3e-06   26.5   0.0    7.9e-06   25.3   0.0    1.7  1  DXP_synthase_N   1-deoxy-D-xylulose-5-phosphate synthase
    4.9e-06   25.7   0.1    7.6e-06   25.1   0.1    1.2  1  E1_dh            Dehydrogenase E1 component
    0.00012   21.9   0.8     0.0088   15.8   1.5    3.2  2  TPP_enzyme_C     Thiamine pyrophosphate enzyme, C-terminal TP
  ------ inclusion threshold ------
      0.081   12.9   0.1       0.16   12.0   0.1    1.5  1  Toxin_ToxA       Proteinaceous host-selective toxin ToxA


Domain annotation for each model (and alignments):
>> Transketolase_N  Transketolase, thiamine diphosphate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  425.1   0.1  6.3e-131  1.6e-127       4     333 ..      33     363 ..      30     364 .. 0.97

  Alignments for each domain:
  == domain 1  score: 425.1 bits;  conditional E-value: 6.3e-131
                      HHHHHHHHHHHHHHHHHT-S--HHHHHHHHHHHHHHHHT--B-TTBTT-TTS-EEEESSGGGHHHHHHHHHHTTS.S--HHHHTTTT..STT-S CS
  Transketolase_N   4 kavnaiRvLavDavekaksGhPGaplgladiaevlfkkllkhnPndpkwidRDRfvLsnGhaslllYsllhLtGy.dlsledlksfr..qlgsk 94 
                      +a+ + R L  D  e+ k+GhPG ++g+a+i+++l+k+++k+ P++p++++RDRfvLsnGh++l++Y++lhL+Gy  +++e+lks++    +s 
       EEA19436.1  33 QALRTFRCLIADLCEQFKGGHPGGAMGMAAIGTALWKYTMKYSPTNPNYFNRDRFVLSNGHTCLFQYTFLHLVGYpAMTMEQLKSYHstRTDSI 126
                      567899*********************************************************************************666789* PP

                      S-SS--TTTSTT--S---STTHHHHHHHHHHHHHHHHHHHH-BTTB-S----EEEEEEHHHHHSHHHHHHHHHHHHTT-TTEEEEEEESSEETT CS
  Transketolase_N  95 tpGhPelghtagvevttGPLGqGianavglalaektlaatynkpgfdivdhytyvilgDgclmeGvsseasslagtlkLgkLivlyDdnkisid 188
                      +pGhPe+ +++g+evttGPLGqG+anavgla+a+k+l a+yn+pgf++v+++t++++gD+cl+eGv+ ea++lag+ kL++L+v+yD+n++++d
       EEA19436.1 127 CPGHPEI-ENDGIEVTTGPLGQGVANAVGLAMATKHLGARYNRPGFEVVNNMTWCMIGDACLQEGVAMEAIQLAGHWKLNNLVVIYDNNQVTCD 219
                      ******5.678*********************************************************************************** PP

                      EEGGGT--S-HHHHHHHTT-EEEEETTT.T-HHHHHHHHHHHHH-TTS-EEEEEE--TTTTSTTTTTSGGGTSS---HHHHHHHHHHTTS-TT- CS
  Transketolase_N 189 GeteisftedvakrfeaygWhvievedg.edveaikaaieeakaekdkPsliklrtviGygspakagtedvhGapLgedevaalkkklGfdpek 281
                      G+++  +tedv+++ +a+gW+vi vedg  dv a++aa+++a+ +  kP++i++rt+iG gs + ag +++hGa+ g+++va++k k+G+dpe+
       EEA19436.1 220 GSVDLCNTEDVNAKMKACGWDVIDVEDGcYDVPALTAALAQARFN-TKPTFINVRTIIGIGS-KVAGDAKAHGAAYGAEDVASIKMKFGMDPEQ 311
                      *************************66537*************99.8***************.99***************************** PP

                      TS---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHTT-- CS
  Transketolase_N 282 sfevpeevydaykekvaegakaeeeWeekfaaykkkapeeaaelerrlsgel 333
                      +f+v++evyd +++ v++g++ e+eW+++++ y++++pe+ +e+  r++g++
       EEA19436.1 312 HFVVQDEVYDFFRDAVHRGEAHENEWKQLLERYAHEYPELHQEFMLRVEGQM 363
                      *************************************************986 PP

>> Transket_pyr  Transketolase, pyrimidine binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.3   0.0     2e-40   5.1e-37       6     176 ..     385     564 ..     381     565 .. 0.94

  Alignments for each domain:
  == domain 1  score: 127.3 bits;  conditional E-value: 2e-40
                   HHHHHHHHHHHHCTTTTEEEEESSTHHHHTTCHCCHHEGGT.............TEGEEE--S-HHHHHHHHHHHHHHCT.TEEEEEEEEHHHHGGG CS
  Transket_pyr   6 rkaeaealaellkedpevvligaDvaggtfsvrkgllhdqg.............egrvidsgisEqavlgfavGaalagp.llviveaqFgdFangA 88 
                   rk  +++ + l  + +++++++aD++ +++ ++kg++++q+             +gr+i+ gi+E+a++ + +G+a+ ++ +  +v   F++F+   
    EEA19436.1 385 RKSAGLCCNPLSSKLQNMMVGTADLTPSVNMAWKGKVDFQHpdlkttcgingdySGRYIHWGIREHAMASISNGLAAFNKgTILPVTSSFFMFYI-- 479
                   67778888889999*********************************************************************************.. PP

                   HHGGHHHHHCHHHHHT--EE.EEESBSGGGSTTGTTTSBSSHHHHHHTSTTEEEE--SSHHHHHHHHHHHHHSSS.SEEEEEE-SSEEC CS
  Transket_pyr  89 qiyadqairsgeakgklkvg.vvtrlpigvgedGpehqsaeleaflrlipglkvvrPsdpaetkhllrrairredrkPvvlrlpksllr 176
                     ya + +r + a+++l+ + + t+++ig+gedGp+hq++ l a++r++p+l  +rP+d +et++++  a+r  ++ P+++ l++++l+
    EEA19436.1 480 --YAAPGVR-MGALQGLQQIhIATHDSIGTGEDGPTHQPIALAALYRAMPNLLYIRPCDSEETAGAFISALR-ATSSPTIISLSRQNLE 564
                   ..*******.66777776666***************************************************.5679**********96 PP

>> Transketolase_C  Transketolase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0     7e-10   1.8e-06       5     122 ..     583     689 ..     579     691 .. 0.81

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 7e-10
                      EEETTSSEEEEEETTHHHHHHHHHHHHHTT.TTCEEEEE-SEEESHHHHHHHHHHHHHSEEEEEEEEESTTSHHHHHHHHHHHCCCTTCSSEEE CS
  Transketolase_C   5 ilregkdvtlvayGsmveealeAaeeLeke.gisaeVvdlrtvkplDketilesvkktgrlvvveeavkrgGigsevaaalaeeafdgldapvk 97 
                      ++ e  dvtl+++G+++ +a++  + L+++ +i+a+Vv+ ++ + +  + i+     ++r v+ +  ++r+ i++  ++ + +    + da ++
       EEA19436.1 583 VEEEDADVTLIGVGAEMVFAMRTRQLLQDKfQIKARVVSFPCQRLFESQSIE-----YKRSVLKYRSTPRVVIEAYAVNGWER----YADAGFS 667
                      678899*********************************************9.....99999999999999999999999988....6666655 PP

                      EEEE-SSSSSSGHHHHHHHTT-SHH CS
  Transketolase_C  98 rvggpdviepgsaeelekafgldae 122
                      +        + + ++ +k+fg+d +
       EEA19436.1 668 MSSFG---HSLPGPAAYKYFGFDEQ 689
                      55333...33333345778877765 PP

>> DXP_synthase_N  1-deoxy-D-xylulose-5-phosphate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.3   0.0   3.1e-09   7.9e-06     107     174 ..     139     216 ..      14     235 .. 0.65

  Alignments for each domain:
  == domain 1  score: 25.3 bits;  conditional E-value: 3.1e-09
  DXP_synthase_N 107 afeagHsstsisaalGlavardlkge..........kkkvvaviGDgaltgGmafealnnigelkkkllvilNdNems 174
                      +++g  +  ++ a+Gla+a+++ g           ++ + ++iGD+ l  G+a+ea++ +g+ k + lv++ dN+++
      EEA19436.1 139 EVTTGPLGQGVANAVGLAMATKHLGArynrpgfevvNNMTWCMIGDACLQEGVAMEAIQLAGHWKLNNLVVIYDNNQV 216
                     3456777889999*******999887566777766669999**********************997766666666654 PP

>> E1_dh  Dehydrogenase E1 component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1   0.1     3e-09   7.6e-06      71     167 ..     113     220 ..      90     274 .. 0.77

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 3e-09
                 HHHTT-TTTSSGTT-.-E..BTT..BEEE-SSTTTHHHHHHHHHHHHH..........HHTS---EEEEEEGGGTT-HHHHHHHHHHHHTT--E.EEEE CS
       E1_dh  71 aeltgkvkgkggsrhelmyaekesrilggngivgaqvplvaGialaak..........iegkkevailliGDgAanqGdvyealnlaalwklpv.ifvv 158
                  +l++  + + +s  +++ + ++  i  + g++g  v  + G+a+a k          +e  ++++ ++iGD+   +G + ea++la  wkl   + + 
  EEA19436.1 113 EQLKSYHSTRTDSICPGHPEIENDGIEVTTGPLGQGVANAVGLAMATKhlgarynrpgFEVVNNMTWCMIGDACLQEGVAMEAIQLAGHWKLNNlVVIY 211
                 45555556666666677767777788889999999988888***************************************************9856777 PP

                 EEESEETTE CS
       E1_dh 159 eNNkygisT 167
                  NN+     
  EEA19436.1 212 DNNQVTCDG 220
                 899976654 PP

>> TPP_enzyme_C  Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   1.5   3.5e-06    0.0088      26     153 .]     141     272 ..     130     272 .. 0.73
   2 ?   -0.8   0.0      0.44   1.1e+03     102     151 ..     507     556 ..     487     558 .. 0.67

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 3.5e-06
                   TTS-TTTHHHHHHHHHHH.........STT.....SEEEEEEEHHHHHHT.GGGHHHHHHT.T-SEEEEEEE-SBCCCHHHHHHHHTCCTTTTSBB. CS
  TPP_enzyme_C  26 glgtmGyglpaAiGakla.........kpd.....revvaivGDGgflmi.lqelatavrr.nlpitvvvlnNegygmtggqqepfggkrksgpagk 106
                   ++g +G g++ A+G+++a         +p+     +  ++++GD +++    +e ++ + + +l+ +vv+++N+   + g            ++   
    EEA19436.1 141 TTGPLGQGVANAVGLAMAtkhlgarynRPGfevvnNMTWCMIGDACLQEGvAMEAIQLAGHwKLNNLVVIYDNNQVTCDGSVDL-------CNT--- 227
                   68999************4455566776443223337999*********9998888888888577*********99865444322.......221... PP

                   BS----HHHHHHHTTSEEEEESS..H.HHHHHHHHHHHHCSSSEEEEEE CS
  TPP_enzyme_C 107 dlkpvdfaklaealGakgarvek..adveeleealkealekkgpaliev 153
                      + d+ + ++a+G +++ ve+  +dv  l +al++a+ + +p++i+v
    EEA19436.1 228 ---E-DVNAKMKACGWDVIDVEDgcYDVPALTAALAQARFNTKPTFINV 272
                   ...2.67777888888888666522577788888888887778888876 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.44
                   TSBB.BS----HHHHHHHTTSE.EEEESSH.HHHHHHHHHHHH.CSSSEEEE CS
  TPP_enzyme_C 102 gpagkdlkpvdfaklaealGak.garvekadveeleealkeal.ekkgpali 151
                   g++g + +p+ +a+l +a+  +  +++++ d ee++ a+  al ++  p++i
    EEA19436.1 507 GEDGPTHQPIALAALYRAM--PnLLYIRPCDSEETAGAFISALrATSSPTII 556
                   3333357788888888888..3244666888899999999999878888877 PP

>> Toxin_ToxA  Proteinaceous host-selective toxin ToxA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.1   6.3e-05      0.16      34      77 ..     198     242 ..     172     272 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 6.3e-05
  Toxin_ToxA  34 aigswelnnlvrvglsrvvdnslrvditntgran.rlivtewdss 77 
                 + g w+lnnlv +  + +v    +vd+ nt   n ++    wd  
  EEA19436.1 198 LAGHWKLNNLVVIYDNNQVTCDGSVDLCNTEDVNaKMKACGWDVI 242
                 5699**************************999834556677755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (722 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       397  (0.0221429); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.64u 0.27s 00:00:00.91 Elapsed: 00:00:00.43
# Mc/sec: 4988.38
//
Query:       EEA19437.1  [L=446]
Description: HET domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.9e-13   49.2   2.6      9e-11   42.3   0.0    2.3  2  HET             Heterokaryon incompatibility protein (HET)
  ------ inclusion threshold ------
      0.086   12.4   0.0       0.14   11.7   0.0    1.3  1  Ribosomal_S3Ae  Ribosomal S3Ae family
       0.14   11.0   0.0       0.21   10.4   0.0    1.1  1  Trp_halogenase  Tryptophan halogenase


Domain annotation for each model (and alignments):
>> HET  Heterokaryon incompatibility protein (HET)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.3   0.0   1.5e-14     9e-11       1      80 [.     288     369 ..     288     385 .. 0.86
   2 !    6.9   0.6    0.0012       7.2     130     146 .]     387     403 ..     370     403 .. 0.84

  Alignments for each domain:
  == domain 1  score: 42.3 bits;  conditional E-value: 1.5e-14
         HET   1 YeaLSYvWgdsk...ekeeievngklleltenledalqvlrk.lgerylWiDaiCInQdddkekskqvqlmadIYsnAelviva 80 
                 Y+a+S+vW d     e +++++   +l+ t+ + d l ++ + +++   WiD +CI  +++++++  ++ ma+ Ys+A++v+v 
  EEA19437.1 288 YVAISHVWSDRLgnpEANALYC--CQLQRTQEMVDGLGHITEsSDPVRFWIDTLCIPVQNEQDRRLAISDMAKYYSEASCVLVL 369
                 9*******88775434566776..899999999999999988688899*********999*********************996 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0012
         HET 130 eellespwfkRvWvlQE 146
                  ++  s+w++R+W+lQE
  EEA19437.1 387 LRISLSTWMRRLWTLQE 403
                 5677799*********9 PP

>> Ribosomal_S3Ae  Ribosomal S3Ae family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   2.4e-05      0.14      75     109 ..     230     264 ..     219     287 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 2.4e-05
                     EEEEESSEEEEEEEEEEE-HHHHHHH--SSB-EEE CS
  Ribosomal_S3Ae  75 ieevqgknaltnFkgmeltrDklrslvrkwsslIe 109
                       +v++k+++ +  g+e+ +Dkl sl rk+ + + 
      EEA19437.1 230 SMQVNDKDCIDSHCGLEVDTDKLSSLLRKGATPVS 264
                     5789**************************99776 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   3.5e-05      0.21     102     184 ..     198     280 ..     185     287 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 3.5e-05
                     EHHHHHHHHHHTT--S-HHHHH-SCHHHHHTTB-SB-TTS-B-S--EEEE-HHHHHHHHHHHHHHCT-EEEE--EEEEEE-TT CS
  Trp_halogenase 102 alhhywlkarargaaeeledysleavaakakkfsprekdglsalsyAyhldaalyakfLrrvaearGvtrvegkvvevqlded 184
                      +  +  + ++ ++ +  e+ +++ ++  + + ++++ +     + ++++d  ++  +Lr+ a+   v+++eg++++v+++ +
      EEA19437.1 198 YFASCISRYKKGNHVNCTETKCITYQVTSEYRSMQVNDKDCIDSHCGLEVDTDKLSSLLRKGATPVSVRSIEGDSEKVKIEIK 280
                     555555666677788889999**************999989999**********************************99864 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (446 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       397  (0.0221429); expected 358.6 (0.02)
Passed bias filter:                      330  (0.0184059); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 3046.61
//
Query:       EEA19438.1  [L=544]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
        0.1   11.8   2.4       0.17   11.1   0.4    2.1  2  Closter_coat   Closterovirus coat protein


Domain annotation for each model (and alignments):
>> Closter_coat  Closterovirus coat protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.4   9.5e-06      0.17      19      91 ..     284     358 ..     267     364 .. 0.78
   2 ?   -0.1   0.1     0.027   4.8e+02      10      46 ..     419     455 ..     411     490 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 9.5e-06
  Closter_coat  19 vkellekfkealktklklsdedilvhlalllyrlanlsTSeKvkyndenty..vidgkevtlkdadlfnvvkslk 91 
                   ++++ ++ +++++ + +l d+ +++hla +  r +  sT +Kvk++ ++ +   +++++++++  +++++ ks+ 
    EEA19438.1 284 LERHKAQRSRFVQLQNELLDSLKAAHLAAVAERRLSNSTAKKVKKEWNTDFlaRMEERQLSVEIDQIKEFEKSKR 358
                   55666677777788889****************************555555448889999999999998888864 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.027
  Closter_coat  10 dasklneeevkellekfkealktklklsdedilvhla 46 
                   ++++l+e   k l+e ++++l++ ++  ++++++ ++
    EEA19438.1 419 SMDRLHEARIKVLRELQEQQLQETTARLEKELDTLIG 455
                   6788999999999999999999999999999888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (544 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1526  (0.0851135); expected 358.6 (0.02)
Passed bias filter:                      440  (0.0245412); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.30s 00:00:00.95 Elapsed: 00:00:00.44
# Mc/sec: 3746.34
//
Query:       EEA19439.1  [L=321]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.5e-67  225.6   0.0    1.1e-66  224.8   0.0    1.4  1  CENP-O         Cenp-O kinetochore centromere component
  ------ inclusion threshold ------
      0.023   14.3   0.4      0.033   13.7   0.4    1.2  1  TBK1_CCD1      TANK-binding kinase 1 coiled-coil domain 1
      0.045   13.6   1.2        1.9    8.2   0.1    2.1  2  KASH_CCD       Coiled-coil region of CCDC155 or KASH
      0.099   12.6   1.1       0.48   10.4   0.1    2.3  2  Tnp_22_trimer  L1 transposable element trimerization domain
       0.11   12.4   1.6       0.81    9.6   0.1    2.1  2  Phage_Mu_Gam   Bacteriophage Mu Gam like protein
       0.68   10.2   4.1        2.1    8.7   0.4    2.3  2  DUF5082        Domain of unknown function (DUF5082)
       0.86    9.8   3.7        1.3    9.3   0.6    2.3  2  TMF_TATA_bd    TATA element modulatory factor 1 TATA binding


Domain annotation for each model (and alignments):
>> CENP-O  Cenp-O kinetochore centromere component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  224.8   0.0   4.4e-70   1.1e-66       1     213 []      93     317 ..      93     317 .. 0.94

  Alignments for each domain:
  == domain 1  score: 224.8 bits;  conditional E-value: 4.4e-70
      CENP-O   1 vTtFrvkDPdpnavdggnvLGiridvfsr.grflepYYvlLkrpseeeke.........lrvhrHTvPafipLaklearylpap.........eeeeea 80 
                 +T F++kDP+p + +++n+LG+ridv+ r g+f++pYYvlL+r++e+ +          ++++rHT+P++ip++kl++rylp+          e+e ea
  EEA19439.1  93 TTLFPWKDPNPYN-ESPNLLGLRIDVCERnGTFAKPYYVLLQRENESPTLplrkqsalsFSIYRHTIPPCIPMEKLAHRYLPQFrpsrrqgaaEDEIEA 190
                 599**********.9****************************9987777888899999***********************9999*****98888899 PP

      CENP-O  81 kkkkektrkqdLkkFvrelrreLvayhnRldavedLrealgleakkteeeeseereeelesrelkivslsaadleakqiriewadgrvgrlvisddGev 179
                  k+k+ktrkqdL++Fvr+lr+eL a+  R+d++++L+e+l+l++ +t  +e+ +r   +++++ ++vsl+a++le +++riew+dgrvgr++is++G v
  EEA19439.1 191 LKTKTKTRKQDLNAFVRHLRKELAAWYARRDSISWLEEQLDLTD-VT--DEHGTR--GQKTNPAQLVSLAATSLESRYVRIEWSDGRVGRFKISNSGLV 284
                 9999***************************************9.33..333333..56899************************************* PP

      CENP-O 180 ekavvigesgkrdkeleeallggdgriedlvkrL 213
                 e+avvige+g rdk++e  l+ggd+ +e+lv+rL
  EEA19439.1 285 ERAVVIGEKG-RDKRTELILMGGDRGVESLVDRL 317
                 **********.********************997 PP

>> TBK1_CCD1  TANK-binding kinase 1 coiled-coil domain 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.4   1.3e-05     0.033      97     169 ..       4      80 ..       1      92 [. 0.77

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.3e-05
   TBK1_CCD1  97 deiselhkkllrlssslerieeslqeiknk..lipeellsdewvkdegsqsedR..nveklkvlldkiteiykqfkk 169
                 + i+++ + l  + s+ ++i e++++++nk  l++  lls+ +v+ e +++++R  +    kv+  ++t   +  +k
  EEA19439.1   4 ETITNIDNTLEAMDSEIAKIRETIKNFQNKrrLLSASLLSSDYVRREIEETNNRsgSGGARKVARMEVTTLLRDARK 80 
                 679**********************998854499********************33233455555555555555555 PP

>> KASH_CCD  Coiled-coil region of CCDC155 or KASH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   0.1   0.00076       1.9      25      73 ..       7      55 ..       3      66 .. 0.91
   2 ?    4.2   0.1     0.013        34      43      82 ..     186     229 ..     183     258 .. 0.74

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.00076
    KASH_CCD 25 skLkkavetaeetnakLteeieeLkkklkstQqalqkaklleeEleelk 73
                + + +++e+++ + ak+ e i++ ++k + +  +l +   +  E+ee  
  EEA19439.1  7 TNIDNTLEAMDSEIAKIRETIKNFQNKRRLLSASLLSSDYVRREIEETN 55
                678899****************************************976 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.013
    KASH_CCD  43 eeieeLkkklkstQq.alqkaklleeEleel...kalvkeleEk 82 
                 +eie+Lk+k k   q +  + + l +El+     + +++ leE+
  EEA19439.1 186 DEIEALKTKTKTRKQdLNAFVRHLRKELAAWyarRDSISWLEEQ 229
                 69********9875515567899*99998532225566666665 PP

>> Tnp_22_trimer  L1 transposable element trimerization domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.1      0.32   8.2e+02      11      29 ..      15      34 ..       6      41 .. 0.73
   2 ?   10.4   0.1   0.00019      0.48      10      27 ..     182     199 ..     179     202 .. 0.88

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.32
                   HHHHHHHHHHHHHH.HHHHH CS
  Tnp_22_trimer 11 aaEDeieeidrevK.ereKr 29
                   a+  ei  i  + K +++Kr
     EEA19439.1 15 AMDSEIAKIRETIKnFQNKR 34
                   88899999999998444444 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00019
                    HHHHHHHHHHHHHHHHHH CS
  Tnp_22_trimer  10 SaaEDeieeidrevKere 27 
                     aaEDeie +++  K r 
     EEA19439.1 182 GAAEDEIEALKTKTKTRK 199
                    69*************985 PP

>> Phage_Mu_Gam  Bacteriophage Mu Gam like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.2     0.075   1.9e+02      27      52 ..       7      32 ..       1      38 [. 0.71
   2 ?    9.6   0.1   0.00031      0.81      34     104 ..     182     255 ..     177     270 .. 0.65

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.075
                  HHHHHHHHHHHHHCHHHHHHHHHHHH CS
  Phage_Mu_Gam 27 eeiaaikekleaeleplkkeieyles 52
                  ++i++  e+ ++e++++ + i+ +++
    EEA19439.1  7 TNIDNTLEAMDSEIAKIRETIKNFQN 32
                  56777777777777777777777765 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00031
                   HHHHHHCHHHHHHHHHHHHHHHHHHHCTHHHH-..----.-EE-SS-EE---------.--TT--..HHHHHHH CS
  Phage_Mu_Gam  34 ekleaeleplkkeieylesllkqYaeankdeLfkdgktK.slklpfGkvgfrkstpkvkkrdkek..eelLeal 104
                    ++e+e+e+lk++ +  ++ l +++ ++++eL     ++ s++    ++ +   t++  +r++++  ++l++ +
    EEA19439.1 182 GAAEDEIEALKTKTKTRKQDLNAFVRHLRKELAAWYARRdSISWLEEQLDLTDVTDEHGTRGQKTnpAQLVSLA 255
                   56778888888888888888888888888888766555556666666666666666666666555655555555 PP

>> DUF5082  Domain of unknown function (DUF5082)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.4   0.00081       2.1      83     110 ..       6      33 ..       3      43 .. 0.88
   2 ?    2.6   0.3     0.059   1.5e+02      22      52 ..     184     215 ..     178     234 .. 0.67

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00081
     DUF5082  83 vdkldelidaieeEIerLenqiseaqgv 110
                 ++++d++  a+++EI +++++i++ q++
  EEA19439.1   6 ITNIDNTLEAMDSEIAKIRETIKNFQNK 33 
                 689********************99986 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.059
     DUF5082  22 leekIerLk.eaktklsdekeslkqkkkklek 52 
                  e+ Ie Lk ++kt+ +d ++ + + +k+l+ 
  EEA19439.1 184 AEDEIEALKtKTKTRKQDLNAFVRHLRKELAA 215
                 57777777777777777777766666666655 PP

>> TMF_TATA_bd  TATA element modulatory factor 1 TATA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.6    0.0005       1.3      11      53 ..       3      45 ..       1      82 [. 0.84
   2 ?    1.0   0.1      0.19   4.9e+02      29      58 ..     193     222 ..     177     246 .. 0.54

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.0005
  TMF_TATA_bd 11 vqlverlsseirrlEgElaslkeelerleaerdeareeivklm 53
                 +++++++  ++  +++E+a+++e++++++++r+ +++ +++  
   EEA19439.1  3 TETITNIDNTLEAMDSEIAKIRETIKNFQNKRRLLSASLLSSD 45
                 67899999**************************999998865 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.19
  TMF_TATA_bd  29 aslkeelerleaerdeareeivklmkenee 58 
                  +++k++ + l+a  + +r+e+++ +++ ++
   EEA19439.1 193 TKTKTRKQDLNAFVRHLRKELAAWYARRDS 222
                  222233333333344444444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (321 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1047  (0.058397); expected 358.6 (0.02)
Passed bias filter:                      789  (0.0440069); expected 358.6 (0.02)
Passed Vit filter:                        93  (0.00518713); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 2204.97
//
Query:       EEA19440.1  [L=1648]
Description: hypothetical protein PMAA_002330 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-08   35.6   0.0    1.1e-08   35.6   0.0    2.6  3  Goodbye   fungal STAND N-terminal Goodbye domain
      3e-06   27.5   0.0    3.4e-05   24.1   0.0    2.6  2  AAA_22    AAA domain
    8.7e-05   23.0   0.0    0.00057   20.3   0.0    2.5  1  AAA_16    AAA ATPase domain
  ------ inclusion threshold ------
      0.039   13.0   0.1       0.18   10.8   0.0    2.2  2  T2SSE     Type II/IV secretion system protein
       0.86    9.3   3.5       0.91    9.2   1.2    2.3  2  RMI1_N    RecQ mediated genome instability protein


Domain annotation for each model (and alignments):
>> Goodbye  fungal STAND N-terminal Goodbye domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.6   0.0     3e-12   1.1e-08       1     115 [.      35     153 ..      35     157 .. 0.86
   2 ?   -3.9   0.0       4.9   1.8e+04       5      26 ..     538     556 ..     514     566 .. 0.59
   3 ?   -3.0   0.4       2.8   9.9e+03      21      47 ..     680     706 ..     670     721 .. 0.45

  Alignments for each domain:
  == domain 1  score: 35.6 bits;  conditional E-value: 3e-12
     Goodbye   1 WeeAlkeyekeTgkdlkdealkelssvedllkqieaekdkfeefr...ekkeklkealkkilspiqllggiaaqgasmaFg.PaslcfnAvsyLikaak 95 
                 W+eA+ + +ke g +l   + +++  +++  ++++++++ fe++r   e+k k+ +a++ +l       ++ ++ +s +++ Pa+++ ++v+y+i+aak
  EEA19440.1  35 WKEAVTRIQKENGVSLPAVSESDSDALQQPDQRLQKASELFEKSRhpdERKTKVIKAVSGCLDWTYSGVTFFKDHVSGTYAaPAQIVAGSVLYMIQAAK 133
                 ****************77777777777777888888888888888555777777777777888878888999*******9879**************** PP

     Goodbye  96 kvseiydaieeLfeelsdfl 115
                 +v+e +d ie  f el+d l
  EEA19440.1 134 NVTEDFDLIESTFVELHDAL 153
                 *****************987 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 4.9
     Goodbye   5 lkeyekeTgkdlkdealkelss 26 
                 lk+++ +T++ +   + k l s
  EEA19440.1 538 LKSFKDSTKEII---KSKLLDS 556
                 455555555555...4444444 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 2.8
     Goodbye  21 lkelssvedllkqieaekdkfeefrek 47 
                 ++++ ++e   + iea+k ++++++++
  EEA19440.1 680 IDTSPKPETENDAIEAQKRRDKNKQKQ 706
                 333334444445555555533333322 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.0   9.6e-09   3.4e-05       6     132 ..     332     496 ..     328     499 .. 0.82
   2 ?   -0.6   0.0      0.42   1.5e+03      92     118 ..    1070    1099 ..     980    1116 .. 0.65

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 9.6e-09
      AAA_22   6 gilvvtGesGtGKTtllrrlleqldeeakaee........erpevvfvtlpsst..sskdllrellralglelka...................erlss 75 
                  +++v G +GtGKT+   r +++ +e+ak ++        ++ ++v++ + +++  +s+++++ l+ +l + +++                   e++s+
  EEA19440.1 332 PVIYVSGATGTGKTFFSYRCFMSIQEQAKKNRleggknnpRQTTLVTYFPFEPGrrDSQSFRNVLAYILVQIADNdgklgdsiakdlaaskiakEEDSK 430
                 589************999999999888888889****87545555555555555788888888877777777777788***************988888 PP

      AAA_22  76 eellealeqalrarav.......ielliiDEaqhlr...seealeeLrsl.lnlsrkgvqliLvGtpe 132
                 + l  + e+ l +++        i  +i+D ++ ++   ++++l+ + +l +  +++g+++++ G p+
  EEA19440.1 431 KKLDFMWEKLLVKKFEktpdtsrILYIILDGVELMDgpdRQAMLSLFQTLnS--DKDGIRILMTGPPD 496
                 88888888888888889999**99***********98755888888866634..59********9995 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.42
      AAA_22   92 ielliiDEa..qhlr.seealeeLrsllnl 118 
                   ++   +Ea  + l  ++e+le+L++++n+
  EEA19440.1 1070 EAIATCEEAlsEELEyTDEILEFLKTIVNI 1099
                  445555554223353449999999999997 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0   1.6e-07   0.00057      17     164 ..     323     482 ..     319     491 .. 0.58

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 1.6e-07
      AAA_16  17 ervrsgrp.elvllsGesGvGKsslv.rellralekd...............ggiflrgkcdqlesaipy.........sa.laqalareellrqllde 88 
                 +++ sg   +++++sG+ G+GK+    r+++ +++++                 +++            y         s+ + ++l +  +l q++d+
  EEA19440.1 323 KSWVSGHKtPVIYVSGATGTGKTFFSyRCFM-SIQEQakknrleggknnprqTTLVT------------YfpfepgrrdSQsFRNVL-A-YILVQIADN 406
                 5666666669****************55555.8888855445544444444312222............122233333344455555.4.455555555 PP

      AAA_16  89 aesaeleawrekleealaavpelagaea.srllellkrll.allsrderplvlvlDdlqwadeaslqllaaLlrlles 164
                 +   +l++  +k ++a ++++e +++++   ++e+l     ++++ ++r l+++lD ++  d  ++q++ +L+++l+s
  EEA19440.1 407 DG--KLGDSIAKDLAASKIAKEEDSKKKlDFMWEKLLVKKfEKTPDTSRILYIILDGVELMDGPDRQAMLSLFQTLNS 482
                 22..2333333333333344444444445444444433333666666777******************7777777666 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   5.1e-05      0.18     131     156 ..     333     358 ..     320     364 .. 0.85
   2 ?   -3.2   0.1      0.93   3.3e+03      96     132 ..     699     736 ..     679     738 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 5.1e-05
       T2SSE 131 lilvsGgTgsGKttllyallkeinks 156
                 +i vsG+Tg+GKt + y +   i+++
  EEA19440.1 333 VIYVSGATGTGKTFFSYRCFMSIQEQ 358
                 689***************99999887 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 0.93
       T2SSE  96 R.kksakeltlddlgaeealkekiaevlrkavrergli 132
                 R k+++k++++++ +++  l++  ++++r +v+++  i
  EEA19440.1 699 RdKNKQKQVRFRQPAFRDYLEQSSNNMIRDPVKAKVDI 736
                 47888999999999999999999999999999998766 PP

>> RMI1_N  RecQ mediated genome instability protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       1.6   5.7e+03      83     100 ..    1166    1183 ..    1164    1209 .. 0.65
   2 ?    9.2   1.2   0.00025      0.91      44     109 ..    1399    1453 ..    1357    1500 .. 0.65

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 1.6
      RMI1_N   83 edigsSaysqlealeave 100 
                  +dig+S+  q e     +
  EEA19440.1 1166 RDIGHSVATQAELAVVYR 1183
                  79******9998644333 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00025
      RMI1_N   44 Dltestnsssvlpaniaeqrksesspa..lkgpvvvQvldiedigsSaysqlealeavergeetrgre 109 
                    + s++++++lp +           +   ++ + +Q++++ di++S+ +q ++ +a e     +++e
  EEA19440.1 1399 TVNGSMEPVPSLPPGK----------SddKDNATSTQIVEVADISTSTSEQTTNSNASE---VLQTKE 1453
                  3334444555555553..........0224677889******************99932...222333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1648 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1115  (0.0621897); expected 358.6 (0.02)
Passed bias filter:                      600  (0.0334653); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 1.00u 0.30s 00:00:01.30 Elapsed: 00:00:00.46
# Mc/sec: 10748.77
//
Query:       EEA19441.1  [L=584]
Description: SD08430p [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     4e-164  547.2  17.7    2.7e-84  283.7   7.0    3.1  3  Acatn     Acetyl-coenzyme A transporter 1


Domain annotation for each model (and alignments):
>> Acatn  Acetyl-coenzyme A transporter 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  283.7   7.0   1.5e-88   2.7e-84       2     226 ..      94     306 ..      93     309 .. 0.93
   2 !   93.7   0.0   5.4e-31   9.7e-27     259     345 ..     304     390 ..     302     393 .. 0.94
   3 !  179.5   0.5   5.5e-57   9.9e-53     375     548 .]     392     576 ..     387     576 .. 0.94

  Alignments for each domain:
  == domain 1  score: 283.7 bits;  conditional E-value: 1.5e-88
       Acatn   2 fylLvvLyllqGiPvGLafgtiPflLkslaketsftelgvfslatyPyslkilWsPivDslyskkiGrrrsWiiPvqlvsgilllvlglaiskglifeg 100
                 f lLv+Ly+lqGiP+GLa+g++PflLk    ++s+ ++gvfsla+yPyslk++WsPivD+++s+++Grr+sWi Pvql+sg+ +l l+           
  EEA19441.1  94 FLLLVLLYFLQGIPMGLAMGSVPFLLKP---HISYGQIGVFSLASYPYSLKLFWSPIVDAVWSRRLGRRKSWITPVQLLSGLAMLYLA---------GR 180
                 89*************************9...9**************************************************999666.........45 PP

       Acatn 101 vddafhgeasekvlkvnilsLtlvflvLvllcatqDiavDgWaltiLskkslsyastaqtvGlnlGyflsftvflslnssdfvnkylr...kvpleygl 196
                 v+++++   s   ++ n+ ++t ++++Lv+lcatqDiavDgWalt++s++++syastaqtvGl  G+fls+tvfl+lns df+n+++r   +   + gl
  EEA19441.1 181 VEAMLN---SAGESDSNVWTFTKWWFFLVFLCATQDIAVDGWALTLISPQNISYASTAQTVGLTAGHFLSYTVFLALNSPDFANRWFRsaaNADPKNGL 276
                 667774...344578899**********************************************************************555455679** PP

       Acatn 197 vslsgylklaGllyllvtlyvvfltkekpl 226
                 +slsgy+ +aG+ y++vt+ ++fl+ke+ +
  EEA19441.1 277 LSLSGYMAFAGWSYIVVTFLLFFLKKEERT 306
                 ***************************975 PP

  == domain 2  score: 93.7 bits;  conditional E-value: 5.4e-31
       Acatn 259 eksektssiksvyrllikvlkLksvrllalihlisklafqcneaatnlkLLekGlkreDlavtvlidvPfeiifgyyvakwssdkek 345
                 e+++++  i+ vyr+++ vlkLk++++++++hli+k++fq nea t+lkL++kG+ ++++a++vlid+Pfei +gyy  +ws++ ++
  EEA19441.1 304 ERTKDKDGIMDVYRSMWSVLKLKNIQMIIVLHLIAKIGFQANEAVTSLKLIDKGFGQDNMALVVLIDFPFEIALGYYAGQWSTEYTP 390
                 56788999**************************************************************************98765 PP

  == domain 3  score: 179.5 bits;  conditional E-value: 5.5e-57
       Acatn 375 tPWlygflgrllaailgsyvvksfPkdgeitksyfllviiqhllgsflstvqfvgisafhtriaDpvlgGtymtllntlsnlGgtWprllvlslidyft 473
                 + W ++f+grl+aai++++ v+ +P  + +   y l+vi  h+l+ f++tv fv++safh+ri+Dp++gGtymtll t+snlGgt+p++++l ++d+ft
  EEA19441.1 392 RLWCWAFVGRLAAAIFAQLTVMIYPAASAVPFWYILVVIAEHILSTFMNTVMFVAVSAFHARISDPAIGGTYMTLLATVSNLGGTFPKFFILKMVDMFT 490
                 56************************************************************************************************* PP

       Acatn 474 iyecvledksketvllkna............skelctkslggkvsivrDgyyvtnllCivlGillyftylkkkaqkLqklpisaWrv 548
                  ++cv + ++ +  +lk+              k  c+   gg++ + +Dgyy+tnllC+++G + ++ y++ +a kLq+lp+ aWrv
  EEA19441.1 491 SATCVPPTTTPDPSTLKGDlitsafscaleaDKSRCQA-GGGQCVVEQDGYYITNLLCVIIGAVTFYIYIRPTALKLQALPLRAWRV 576
                 *****999999888888778889999999855555655.899*******************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (584 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       567  (0.0316247); expected 358.6 (0.02)
Passed bias filter:                      310  (0.0172904); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 3898.57
//
Query:       EEA19442.1  [L=605]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.7e-21   75.0   0.0    1.1e-20   73.8   0.0    1.6  1  DUF3176   Protein of unknown function (DUF3176)
     0.0094   14.8   0.0      0.014   14.2   0.0    1.2  1  Nup188_C  Nuclear pore protein NUP188 C-terminal domain


Domain annotation for each model (and alignments):
>> DUF3176  Protein of unknown function (DUF3176)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.8   0.0   1.3e-24   1.1e-20       2      92 ..      80     171 ..      79     184 .. 0.86

  Alignments for each domain:
  == domain 1  score: 73.8 bits;  conditional E-value: 1.3e-24
     DUF3176   2 villasdgkplskWpskitlnvliailstvakaalllavaegisqlkWrwfsekprplsdleafdeasrGpwgalkllwrlkl..aslgallt 92 
                 v+l + +g+pl++ +++it+n++i +l+t+ +a+ll++v+++++q+kW+++ e +rp+ ++e++d+asrGp+g+ kl++ +k+  ++   + +
  EEA19442.1  80 VVLNVLNGRPLPDLQYGITPNAIIGLLATFGQALLLMPVSSALGQMKWLQALE-KRPMDNFETLDKASRGPLGSTKLIVGRKSglWTYTTIYL 171
                 8999***********99**********************************96.6************************98886544333333 PP

>> Nup188_C  Nuclear pore protein NUP188 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.0   1.6e-06     0.014     134     178 ..     394     438 ..     378     494 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 1.6e-06
                 HHHHHHHHCCGG-TTSS-HHHHHHHHHHHHHCTSHHHHHHHHHCT CS
    Nup188_C 134 vatsLfSWsdklavegDPvYGeLsilfLleLSslpalAEqlAvdg 178
                 + t Lf W+++   e DP YG   i+f  + Ss p +   lAv g
  EEA19442.1 394 YETELFTWTNQTIPEFDPTYGHTDIIFQSHDSSTPFVVKSLAVGG 438
                 6799**************************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (605 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       447  (0.0249317); expected 358.6 (0.02)
Passed bias filter:                      379  (0.0211389); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.21s 00:00:00.78 Elapsed: 00:00:00.39
# Mc/sec: 4625.88
//
Query:       EEA19443.1  [L=265]
Description: essential protein Yae1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.2e-13   48.8   0.1    9.2e-13   47.7   0.1    1.6  1  Yae1_N    Essential protein Yae1, N terminal


Domain annotation for each model (and alignments):
>> Yae1_N  Essential protein Yae1, N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.7   0.1   5.1e-17   9.2e-13       1      39 []      97     135 ..      97     135 .. 0.98

  Alignments for each domain:
  == domain 1  score: 47.7 bits;  conditional E-value: 5.1e-17
      Yae1_N   1 GYreGiaeGkeqglqeGfdeGyqeGaqlGlelGqilGvl 39 
                 GYr+Gi+++k +++q Gfd Gy++Gaq Gl++G ilG+l
  EEA19443.1  97 GYRDGITASKSEHVQRGFDAGYPVGAQFGLRVGTILGIL 135
                 9************************************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (265 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1035  (0.0577277); expected 358.6 (0.02)
Passed bias filter:                      541  (0.0301746); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.40
# Mc/sec: 1968.88
//
Query:       EEA19444.1  [L=591]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (591 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       551  (0.0307323); expected 358.6 (0.02)
Passed bias filter:                      266  (0.0148363); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 3866.65
//
Query:       EEA19445.1  [L=910]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (910 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1424  (0.0794244); expected 358.6 (0.02)
Passed bias filter:                      448  (0.0249875); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.95u 0.35s 00:00:01.29 Elapsed: 00:00:00.54
# Mc/sec: 5098.06
//
Query:       EEA19446.1  [L=305]
Description: mitochondrial metallochaperone Sco1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.6e-49  165.8   0.0    7.2e-49  165.1   0.0    1.3  1  SCO1-SenC      SCO1/SenC
    8.5e-05   22.5   0.0    0.00015   21.7   0.0    1.4  1  AhpC-TSA       AhpC/TSA family
  ------ inclusion threshold ------
      0.014   15.7   0.0      0.029   14.7   0.0    1.6  1  Thioredoxin_8  Thioredoxin-like


Domain annotation for each model (and alignments):
>> SCO1-SenC  SCO1/SenC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  165.1   0.0   1.2e-52   7.2e-49       1     134 []     134     272 ..     134     272 .. 0.94

  Alignments for each domain:
  == domain 1  score: 165.1 bits;  conditional E-value: 1.2e-52
   SCO1-SenC   1 ggpFelvdqdgeavteedlegkpslvffgFthCpdvCpttlanmaevldalgee...aekvqplfiTvDPerDtpevlkeyleafdpriigltGskeei 96 
                 ggpF l d dg+++t edl+gk+s+v+fgFthCpd+Cp +l +ma+++d+++e    ae ++p+fiT+DP+rDtpevlk+yl++f+p+iigltG+ +++
  EEA19446.1 134 GGPFVLKDLDGKEFTAEDLKGKYSFVYFGFTHCPDICPDELDKMAAIIDKVKEGsngAEVMRPVFITCDPARDTPEVLKKYLAEFHPDIIGLTGTYQQV 232
                 689************************************************9984434889************************************** PP

   SCO1-SenC  97 akaakefrvyvekvedees..dytvdHsssvyLvdpdgrv 134
                 ++++k++rvy+++ e+ +   dy+vdHs ++yL+dp+g++
  EEA19446.1 233 KQVCKAYRVYFSTPENVKPgeDYLVDHSIYFYLMDPEGDF 272
                 **********88877766557****************986 PP

>> AhpC-TSA  AhpC/TSA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.7   0.0   2.5e-08   0.00015       8     104 ..     137     245 ..     134     270 .. 0.84

  Alignments for each domain:
  == domain 1  score: 21.7 bits;  conditional E-value: 2.5e-08
                 -EEESTTCEEEECHHHTTSEEEEEEESTST-C.CHHHHHHHHHHCHHHCC..CTTEEE...EEEESSSCHHHHHHHHH-H........SSEEEE-TTSH CS
    AhpC-TSA   8 felknadgetvslsdykgkpvvlffypkdwcp.vCttelpalaklyeefk..ergvev...igvsvdspeshkkfiekes.......lnfpllsDeegk 93 
                 f lk+ dg++++ +d+kgk+  ++f  + +cp  C++el ++a+ +++ k  ++g+ev   + +++d+  +  +  +k+        + ++  + + ++
  EEA19446.1 137 FVLKDLDGKEFTAEDLKGKYSFVYFGFT-HCPdICPDELDKMAAIIDKVKegSNGAEVmrpVFITCDPARDTPEVLKKYLaefhpdiIGLTGTYQQVKQ 234
                 889**********************999.89857**************996567998844468999999988888888887777888888888888888 PP

                 HHHHTT-EETT CS
    AhpC-TSA  94 vakaygvlkee 104
                 v+kay v+++ 
  EEA19446.1 235 VCKAYRVYFST 245
                 88888888765 PP

>> Thioredoxin_8  Thioredoxin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   0.0   4.8e-06     0.029       1      60 [.     154     221 ..     154     271 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 4.8e-06
                    .SEEEEEE--SSSHH.HHHHHHHHHHHHHHHHH....TTSEEEEEEE-S...S-HHHHHHHGGGS-TT CS
  Thioredoxin_8   1 gkvvlLyfgaswcpp.ckaftpklkelyeklkk....kkkveivyvsld...kkeeefekylkknkkp 60 
                    gk+ ++yfg ++cp+ c + + k+ ++ +k+k+    +  ++ v++ +d    + e  +kyl++ +++
     EEA19446.1 154 GKYSFVYFGFTHCPDiCPDELDKMAAIIDKVKEgsngAEVMRPVFITCDparDTPEVLKKYLAEFHPD 221
                    6999***********9****************7777899999******95433456777777777544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (305 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       679  (0.0378716); expected 358.6 (0.02)
Passed bias filter:                      579  (0.032294); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.30s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2011.50
//
Query:       EEA19447.1  [L=676]
Description: polysaccharide deacetylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.2e-32  110.2   0.0    9.7e-32  109.6   0.0    1.3  1  MoaE             MoaE protein
    1.8e-20   73.1   0.0    3.5e-20   72.2   0.0    1.4  1  Polysacc_deac_1  Polysaccharide deacetylase
  ------ inclusion threshold ------
      0.058   13.6   0.0       0.49   10.6   0.0    2.1  2  ThuA             Trehalose utilisation
      0.062   12.9   0.0       0.13   11.9   0.0    1.6  1  DUF2334          Uncharacterized protein conserved in bacteri


Domain annotation for each model (and alignments):
>> MoaE  MoaE protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  109.6   0.0   2.2e-35   9.7e-32       1     113 []     523     636 ..     523     636 .. 0.98

  Alignments for each domain:
  == domain 1  score: 109.6 bits;  conditional E-value: 2.2e-35
                 EESS---HHHHHHHH--TT--EEEEEEEE------TS-EEEEEECC-HHHHHHHHHHHHHHHHCCC.TTSEEEEEEE-EEEETTSEEEEEEEEESSHHH CS
        MoaE   1 lteepldvaeiealvaspkaGAvvlFvGtvRdsfdgkkvteLeyeayepmaektleeiaeearerw.elervavvHrlGelevgeasvvvavssahRke 98 
                 lt++pld++ i + ++sp+aGA +lF+Gt+Rd+f+ + v++L+y+ay+p+a+ktl++ia+++ +r+ ++++v + HrlG ++v+eas+ vavssahR  
  EEA19447.1 523 LTHSPLDTTLILSQISSPAAGANILFLGTTRDTFEHRPVSQLSYSAYAPLALKTLTSIARDTFQRYeGIKGVSISHRLGVVPVTEASIAVAVSSAHRGP 621
                 6899**************************************************************77******************************* PP

                 HHHHHHHHHHHHHHH CS
        MoaE  99 afeaceylidelKkr 113
                  ++a+e++++++K+r
  EEA19447.1 622 GWRAAEDVLERCKER 636
                 *************86 PP

>> Polysacc_deac_1  Polysaccharide deacetylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.2   0.0   7.7e-24   3.5e-20       4     116 ..     206     323 ..     204     326 .. 0.90

  Alignments for each domain:
  == domain 1  score: 72.2 bits;  conditional E-value: 7.7e-24
                      TTSTEEEEEEEESSCSCHHHHHHHHHHCT--EEEEE-HHHHCH-....HHHHHHHHHTTEEEEE--SS--EGGGSHHH.HHHHHHHHHHHHHHH CS
  Polysacc_deac_1   4 kgkksvalTfDdgprdntteilpvLkkykvkatffvigglvedy....pdevremaasGveignHtinhsnlkrlsee.evrreierakdalrk 92 
                      k ++s a   Ddg +   +e++++L+++++k tffv+g+  +d      ++  em ++G++i+ H+ +h++++ l++e e+++ei   ++al++
       EEA19447.1 206 KRPNSFAFGIDDGDPALAQEVMEILEDEDIKVTFFVVGRGLKDPstnfTNLYSEMLEKGHQIALHSDTHPKMEGLQSEdEIDDEITGGQHALKD 299
                      5667778889*****************************7555555569***********************99988879************** PP

                      HHS----EEE-GGGEE-HHHHHHH CS
  Polysacc_deac_1  93 algreprlfryPygsasatvleva 116
                       lg e+r+fr+Pyg   a+++e +
       EEA19447.1 300 LLGVESRYFRPPYGTVGARMRERL 323
                      ***************999987765 PP

>> ThuA  Trehalose utilisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.0   0.0      0.19   8.7e+02     115     140 ..     265     290 ..     208     300 .. 0.85
   2 ?   10.6   0.0   0.00011      0.49      56     154 ..     342     489 ..     336     514 .. 0.70

  Alignments for each domain:
  == domain 1  score: -0.0 bits;  conditional E-value: 0.19
                 ........TSGGGTT--.SEEEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxx RF
        ThuA 115 atvkvedrshpateglpeewertdew 140
                 +++  + ++hp +egl++e e+ de+
  EEA19447.1 265 HQIALHSDTHPKMEGLQSEDEIDDEI 290
                 455567789*******9999999996 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00011
                 EE-G..GS-HHHHHH.HHHHHHTT-EEEEEGGG.GS.....HHHH.HH-SEEEEET........................................... CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxx.......................................... RF
        ThuA  56 flstegevldaaqeaalqryveaGgGfvglhsA.adaeerskwfsgLiGarfvghpp.......................................... 111
                 +l+++ +     q +a++r ve Gg +v++h   ++     k+f+++i    ++ ++                                          
  EEA19447.1 342 WLWAN-TDEPWRQLKAFRRDVERGGDLVVMHYLtWS---TVKYFRDFIDIVKQKGKQimridqcmmdadapelssveswnehreskilrtqfhsqpehe 436
                 56664.3446789999***************99555...568999998664444433566778888889999999999999999999******999999 PP

                 ...........................TSGGGTT--.SEEEEEEEEE.-S---SE..EEE CS
                 ..............xxxxxxxx.xxx.xxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxx RF
        ThuA 112 ..............vqeatvkv.edr.shpateglpeewertdewYn.fkpnprgvhvla 154
                                   t ++  dr  hpat+ l+  +++t   +n f   pr+++   
  EEA19447.1 437 dyssgdyyfctnksL--STSTIlSDRtPHPATSRLN--FDITCTTFNyF---PRETTYTT 489
                 999999999875321..44444366679******96..88886667734...44422222 PP

>> DUF2334  Uncharacterized protein conserved in bacteria (DUF2334)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   2.9e-05      0.13      14     124 ..     219     311 ..     213     388 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 2.9e-05
     DUF2334  14 dleklkeiadyldkegipfsvavIPrykdpktgskvnlsenpefvevLkylqakGgeialHGYtHqygtvksevsgegfeflseseakeriekGieilk 112
                 d++  +e+ ++l++e i+++ +v+ r  +           +++f ++  ++ +kG++ialH  tH   +        g+  +se+e  + i+ G   lk
  EEA19447.1 219 DPALAQEVMEILEDEDIKVTFFVVGRGLKD---------PSTNFTNLYSEMLEKGHQIALHSDTHPKME--------GL--QSEDEIDDEITGGQHALK 298
                 6677899999*************9986544.........46789999******************9982........33..346677788888888887 PP

     DUF2334 113 kl.gikpkgFeaP 124
                 +l g++ ++F +P
  EEA19447.1 299 DLlGVESRYFRPP 311
                 7426777777777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (676 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       532  (0.0296726); expected 358.6 (0.02)
Passed bias filter:                      469  (0.0261587); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.42
# Mc/sec: 4888.60
//
Query:       EEA19448.1  [L=593]
Description: DEAD/DEAH box RNA helicase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.5e-40  138.8   0.0    2.7e-40  138.0   0.0    1.4  1  DEAD        DEAD/DEAH box helicase
    1.2e-28   99.6   0.0    5.1e-28   97.6   0.0    2.1  3  Helicase_C  Helicase conserved C-terminal domain
    0.00091   18.1   0.0      0.022   13.5   0.0    2.1  2  UTP25       Utp25, U3 small nucleolar RNA-associated SSU proc
  ------ inclusion threshold ------
      0.057   13.4   0.0       0.16   11.9   0.0    1.9  1  ResIII      Type III restriction enzyme, res subunit


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.0   0.0   6.1e-44   2.7e-40       1     174 [.     153     344 ..     153     346 .. 0.87

  Alignments for each domain:
  == domain 1  score: 138.0 bits;  conditional E-value: 6.1e-44
                 -HHHHHHHHHHHTTCEEEEEESTTSSHHHHHHHHHHHHHHHS....TTSTS...................-EEEEEESSHHHHHHHHHHHHHHTTTSTS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxx...................xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   1 tdiQaeaiplilgggdvlvaaeTGsGKTlaflipvlqivyet....kgktg...................pkalivePtreLaeqtlnnlkkfkkyidl 76 
                 t+iQa  ip+il+g+d+l+ a+TGsGKT+a+l+p+l++++ +        +                   p +l+++PtreLa q+++++++++     
  EEA19448.1 153 TPIQAYGIPAILEGRDLLAVAQTGSGKTAAYLVPILSKLMGKakklA---AprpnitegfepkvhavraePLVLVIVPTRELACQIFDEARRLCYRSMF 248
                 89*************************************87555550...15555666666666666666*************************9889 PP

                 EEEEEETTSSHHHHHHHHHTTCSEEEEEHHHHHHHH.HCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  77 rvlliiggvaardqlskldngvdivvgtpgrlddll.stgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlpkdvk 174
                 r ++ +gg + ++q+ +l++g+di++gtpgrl+d++ + + l+l++vr+ V+DEad+ll+ + + +  ++l+  +  ++d  ++++ +++SAT++k+ +
  EEA19448.1 249 RPCVAYGGGPVSHQRMELQKGCDILIGTPGRLIDFMgQPHVLSLRRVRYTVIDEADELLNYDWETEFTQLLSGGD-SNED--ADHRYMMFSATFNKTCR 344
                 **********************************88677889*******************99999999999984.3333..4577********98765 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       2.3     1e+04      19      58 ..     222     265 ..     216     276 .. 0.57
   2 ?   -2.6   0.0       1.6     7e+03      12      45 ..     325     362 ..     314     373 .. 0.59
   3 !   97.6   0.0   1.1e-31   5.1e-28       3     111 .]     383     494 ..     381     494 .. 0.93

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 2.3
                 EEEEESSHH.HHHH...HHHHHHHTTSTEEEESTTSTHHHHHHH CS
  Helicase_C  19 ilifvntid.rlek...vklllekkgikvavlhgelpqnereei 58 
                 +l++v+t++  ++    ++ l+ ++ ++ +v +g  p ++++  
  EEA19448.1 222 VLVIVPTRElACQIfdeARRLCYRSMFRPCVAYGGGPVSHQRME 265
                 67888888854422333344444446777777776666655554 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.6
                 HTTTTSEEEEEESSHH.HHHH..HHHHHHHT..TSTEEE CS
  Helicase_C  12 leeeggkilifvntid.rlek..vklllekk..gikvav 45 
                 +e  +++ ++f+ t + ++ +   k+l e+    i+v +
  EEA19448.1 325 NEDADHRYMMFSATFNkTCRQvaKKYL-EHGyvRIRVGR 362
                 566677788888888765554545555.33335555555 PP

  == domain 3  score: 97.6 bits;  conditional E-value: 1.1e-31
                 HHHHHHHHHHTTTTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSS....H CS
  Helicase_C   3 leallellkleeeggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprn....v 97 
                  ++l++ll l+    ++lifvnt+ ++++++ +l ++g+ ++ +h++ +q+ere+++++f++g++ +Liat v +rG+di++v +Vinfdlp +    +
  EEA19448.1 383 EQCLYDLL-LSMPPARTLIFVNTKAQADRLDDFLYNRGLPSTSIHSDRTQREREDAMSAFRSGKTPILIATGVSSRGLDIKNVMHVINFDLPSSdqggI 480
                 67899999.99**************998877887899*******************************************************5544569 PP

                 HHHHHHHTTSSSTT CS
  Helicase_C  98 tsyiqriGRtgRag 111
                 ++y++riGRt+R+g
  EEA19448.1 481 DEYVHRIGRTARIG 494
                 ************97 PP

>> UTP25  Utp25, U3 small nucleolar RNA-associated SSU processome protein 25
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.0     0.013        58      75      94 ..     219     238 ..     202     247 .. 0.87
   2 !   13.5   0.0     5e-06     0.022     302     414 ..     364     477 ..     315     504 .. 0.81

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.013
       UTP25  75 rpkvLillptreaalevvel 94 
                  p vL+++ptre a+++ ++
  EEA19448.1 219 EPLVLVIVPTRELACQIFDE 238
                 588************99775 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 5e-06
       UTP25 302 esivdepdarfkfftekilpqlkk...ssskssgiliyipsyfdfvrvrnylkeekvsfaaiseysskkevsraRelFfkgkkkvlLyteRlhffrRyk 397
                  s ++++++r+ +  +++ +q       s    ++li++ +  +  r++++l ++ +  ++i+   +++e + a ++F +gk+ +l+ t      r  +
  EEA19448.1 364 GSSHANIEQRVYYADDSVKEQCLYdllLSMPPARTLIFVNTKAQADRLDDFLYNRGLPSTSIHSDRTQREREDAMSAFRSGKTPILIATGVS--SRGLD 460
                 4556666777766655555554433333677899*******************************************************966..5999* PP

       UTP25 398 ikgvkkvilYklPenpe 414
                 ik+v +vi ++lP+  +
  EEA19448.1 461 IKNVMHVINFDLPSSDQ 477
                 *************9765 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   3.6e-05      0.16      26     141 ..     168     303 ..     150     341 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 3.6e-05
                 EEEEEESTTSTHHHHH.HHHHHHH-S...........................-EEEEESSHHHHHHHHHHGGGGTGG.........GEEEESSS-B-- CS
      ResIII  26 rglikmaTGtGKTlva.aklierllkkgkee......................kflflvprkslleqtleefkkflseayke.....igkkvsgdkkka 96 
                  +l ++ TG+GKT  + + +  +l+ k+k+                        +l++vp+++l  q  +e +++      +      g+ vs ++ + 
  EEA19448.1 168 DLLAVAQTGSGKTAAYlVPILSKLMGKAKKLaaprpnitegfepkvhavraepLVLVIVPTRELACQIFDEARRLCYRSMFRpcvayGGGPVSHQRMEL 266
                 5788999*********66677778877665599*******************99**************9988655444333323222333344444443 PP

                 .......-SEEEEEHHHHHHTH........HHHTTT-SEEEEETG CS
      ResIII  97 kekdstnkkilvttiqsldadseeeeeeseellrdrfdviiiDEa 141
                     ++ ++il+ t  +l   +     + + l+  r  + +iDEa
  EEA19448.1 267 ----QKGCDILIGTPGRLIDFM----GQPHVLSLRRVRYTVIDEA 303
                 ....566666666666666665....5555555555555666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (593 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       436  (0.0243181); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.46
# Mc/sec: 3879.38
//
Query:       EEA19449.1  [L=583]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.7e-36  124.5   0.0    1.3e-35  122.7   0.0    2.0  2  Glyoxal_oxid_N  Glyoxal oxidase N-terminus
    2.1e-20   72.8   0.0    4.4e-20   71.8   0.0    1.6  1  DUF1929         Domain of unknown function (DUF1929)


Domain annotation for each model (and alignments):
>> Glyoxal_oxid_N  Glyoxal oxidase N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  122.7   0.0   1.5e-39   1.3e-35      38     240 .]     103     327 ..      81     327 .. 0.85
   2 ?   -2.4   0.0      0.24   2.2e+03     120     136 ..     367     383 ..     343     441 .. 0.61

  Alignments for each domain:
  == domain 1  score: 122.7 bits;  conditional E-value: 1.5e-39
  Glyoxal_oxid_N  38 kalkkdCtaHsveydvatnavrplkvltdtwcssgalladGtlvqtGG..........fkdgerkvrllspc.....eecdwvelkeelaekRwy 117
                      +l++  +a+s ey+++tn+ + l+++t+++cs g++ladG+l + GG            dg + +r+l           +w e  + l++ Rwy
      EEA19449.1 103 LVLDNGQYAYSAEYNLTTNTAHGLALNTNAFCSGGSFLADGRLASIGGngplpeidstVGDGFQGIRYLGRGvyyddLYDNWYEPGHLLSTPRWY 197
                     45566779****************************************444443333336999******998787643467************** PP

  Glyoxal_oxid_N 118 atnqiLpdgrvivvGG...........rrafsyefvpkeekseekavelpfLketedkeennLYPfvhllpdgnlfifankrsilldykknkvvr 201
                     a+ q+L d+r++v  G            ++ ++e + +++  +++++ lp+L++ +      +YPf+hll +g+lfif  + + ++++++++   
      EEA19449.1 198 ASVQMLQDNRLFVASGslngmdpmqneNNNPTFEILDADGIPANESTILPILSSNQ---PYYMYPFLHLLKNGQLFIFVSRSAEIYNPDSQETSL 289
                     *************9884433443332224568999999999999999999998765...679********************************* PP

  Glyoxal_oxid_N 202 efpklpggernyPssgssvlLplklkeeaseaevlvCGG 240
                     ++p+lpg  r+yP++g svlLpl++ e+  e e+++CGG
      EEA19449.1 290 RLPNLPGTYRTYPNTGGSVLLPLSK-ENDWEPEIIICGG 327
                     ************************5.7799********9 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.24
  Glyoxal_oxid_N 120 nqiLpdgrvivvGGrra 136
                       +Lpdg+v+ + G r+
      EEA19449.1 367 GLLLPDGKVLWLNGARR 383
                     45555555555544443 PP

>> DUF1929  Domain of unknown function (DUF1929)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.8   0.0     5e-24   4.4e-20       1      94 [.     481     580 ..     481     582 .. 0.88

  Alignments for each domain:
  == domain 1  score: 71.8 bits;  conditional E-value: 5e-24
     DUF1929   1 RPkissv.ptevkygetftvtvsvekeaeevkvslvrpgfvTHsvnmdqRlveLev.set.....gytvtvtaPpnanvapPGyymlFvvndgvpSvgk 92 
                 RP+  ++ +t+++ +++f +t++ +++++++k++l++ gfvTH ++m+qRlv+Le  +       ++ v+v++P+++++ap+G+y+++vv dgvp+ g+
  EEA19449.1 481 RPQDIKFsQTNLTTDGEFVITFTSATNSTDLKIALYHGGFVTHLLHMGQRLVFLENeG-FspgleEQVVNVSMPASSSIAPSGPYVIYVVLDGVPGLGQ 578
                 7854555477899**********98889999***********************9850.24556689******************************** PP

     DUF1929  93 wV 94 
                 +V
  EEA19449.1 579 FV 580
                 99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (583 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       279  (0.0155614); expected 358.6 (0.02)
Passed bias filter:                      265  (0.0147805); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.41
# Mc/sec: 4222.43
//
Query:       EEA19450.1  [L=450]
Description: pantothenate kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     5e-144  479.5   0.1   6.2e-144  479.2   0.1    1.1  1  Fumble    Fumble


Domain annotation for each model (and alignments):
>> Fumble  Fumble
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  479.2   0.1  3.4e-148  6.2e-144       1     330 []      73     405 ..      73     405 .. 0.96

  Alignments for each domain:
  == domain 1  score: 479.2 bits;  conditional E-value: 3.4e-148
      Fumble   1 hiavDiGgsLaKlvYfsrkkkksaaekekeeeveeeeeseelggrLhfikfetekieevleflkelllkskekekkkk....tikaTGGGaykyaelik 95 
                 h+avDiGgsLaKlvYf+r                 e++s++ ggrL+fikfete+i++++ef+k+l +++++ + +      ++ aTGGGayky++++k
  EEA19450.1  73 HVAVDIGGSLAKLVYFTR-----------------EISSQSDGGRLNFIKFETERIDRCIEFIKQLKEDHERLNGS-VpdelCVVATGGGAYKYYDKLK 153
                 79****************.................5577889************************8777666444.24888***************** PP

      Fumble  96 eelgvevekedemeclikGlkfllteipkevftyseekpkkavekkeseeiyPylLvniGSGvsilkvegeekfervgGtslgGgtfwGLlslLtgaks 194
                 e+l+v++ +edem+cli+Gl+f++teip+evf+yse++p+k++e+  + ++yPylLvniGSGvs++kv+g+++f+rvgGt+lgGgtfwGL+ lLtga++
  EEA19450.1 154 ETLKVDILREDEMDCLITGLNFFITEIPNEVFSYSETEPMKFAEP--NGSVYPYLLVNIGSGVSMIKVSGPKEFQRVGGTHLGGGTFWGLMALLTGATT 250
                 ***********************************8789**9999..889************************************************* PP

      Fumble 195 fdellelaekGdnskvDmlvgDiyGedyekiglksdliassfgkvfkkkkkkeeeek...................eDiarslLyaisnnigqiaylqa 274
                 fd++l++a++Gdns vDmlvgDiyG dy+kiglks++ias+fgkv k k+++e++ +                   +D++rslL+aisnnigqiaylq+
  EEA19450.1 251 FDDMLAMADRGDNSGVDMLVGDIYGMDYNKIGLKSTAIASTFGKVLKLKRSAEQRAEdgsdlgedpedtppvqfshADMSRSLLFAISNNIGQIAYLQS 349
                 ***********************************************99887777779***************************************** PP

      Fumble 275 klhnlkriyFgGsfirgheqtmktlsyaikfwskgelkalFlrHegylGavGaflk 330
                 ++h+lk+iyFgGsfirgh qtm+tlsyaikfwskge++a+FlrHegylGavGaflk
  EEA19450.1 350 EKHELKHIYFGGSFIRGHLQTMNTLSYAIKFWSKGEKQAYFLRHEGYLGAVGAFLK 405
                 ******************************************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (450 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       508  (0.028334); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 3020.98
//
Query:       EEA19451.1  [L=434]
Description: hypothetical protein PMAA_002440 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (434 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.47
# Mc/sec: 2749.64
//
Query:       EEA19452.1  [L=499]
Description: phosphatidylinositol:UDP-GlcNAc transferase PIG-C [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.6e-133  444.5   4.5   1.8e-133  444.3   4.5    1.0  1  GPI2      Phosphatidylinositol N-acetylglucosaminyltransferas
  ------ inclusion threshold ------
        1.7    8.6   9.2        3.3    7.6   0.0    3.3  3  DUF2975   Protein of unknown function (DUF2975)


Domain annotation for each model (and alignments):
>> GPI2  Phosphatidylinositol N-acetylglucosaminyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  444.3   4.5    2e-137  1.8e-133       1     280 []     110     488 ..     110     488 .. 0.99

  Alignments for each domain:
  == domain 1  score: 444.3 bits;  conditional E-value: 2e-137
        GPI2   1 WkKlLwvkqsypDnYtd.etFleeLqrnprvkpydfwplvadstvivqhvcsviifvlvFvgiyqervspvsvvllssiltvlgwllwelwaskee... 95 
                 WkKlLwv+qsypDnYtd etFl++Lqrnpr++pydfwplvadstvivqhvcsv+ifv++Fvgi+q+r+spvsvv+ +si t+lgw+lw++w++ke+   
  EEA19452.1 110 WKKLLWVRQSYPDNYTDvETFLDHLQRNPRLRPYDFWPLVADSTVIVQHVCSVVIFVCCFVGIFQSRISPVSVVGSGSIGTLLGWVLWDTWVWKEQnea 208
                 *************************************************************************************************** PP

        GPI2  96 ...........................................................................................srssraqq 103
                                                                                                            s s+r++q
  EEA19452.1 209 ikaaqfadsgevddgssasstasqtpaagpqtndhaggnvhglgldlprsdsevhlrrrstgvsvasfqsmtpgsssvlgqpsfyayddnkSLSPRNRQ 307
                 ******************************************************************************************999****** PP

        GPI2 104 rlktiksalliyftllglSPiLksLTkstssDSIwalsfwlllinifffdysiekkkskekeeklvaslStnaalmastvLASRLpstlqVFslllfsi 202
                 rl+tiksalliy++llglSPiLksLTkst+sDSIwals+wl++inif+fdys+++ +++   +k++aslStnaalmastvLASRLpst++VFsl+lfsi
  EEA19452.1 308 RLATIKSALLIYCALLGLSPILKSLTKSTASDSIWALSCWLMIINIFSFDYSSSEGQVDA--TKFPASLSTNAALMASTVLASRLPSTTHVFSLTLFSI 404
                 ****************************************************77777664..56*********************************** PP

        GPI2 203 evfglfPvfrrslrhrswrlhvvltvllvllagagvgiilk......lllavvlllllalimgvcpwwliglqkykneiyGpWD 280
                 evfglfPvfrr+lrh sw+ hv+lt++lvl+agagvgi l+      +++a++ ++l+al+mg c+wwli+lqkykn + GpWD
  EEA19452.1 405 EVFGLFPVFRRQLRHVSWTGHVLLTFALVLTAGAGVGIALRggwaaaIVGAILSTILTALAMGSCSWWLISLQKYKNVVIGPWD 488
                 ***********************************************************************************9 PP

>> DUF2975  Protein of unknown function (DUF2975)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.1     0.014   1.3e+02      20      38 ..     157     175 ..     127     182 .. 0.79
   2 ?    7.6   0.0   0.00037       3.3      43      75 ..     293     325 ..     286     359 .. 0.78
   3 ?    0.3   3.2     0.068   6.1e+02      55     111 ..     416     471 ..     412     476 .. 0.66

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.014
     DUF2975  20 vlllgvlallafvvalvql 38 
                   +++v+++++++v+++q 
  EEA19452.1 157 QHVCSVVIFVCCFVGIFQS 175
                 6789999999999999885 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.00037
     DUF2975  43 rsirkgevFspanvrrLrriglaliaaalllaa 75 
                  ++++++  sp+n +rL +i+ al+++++ll +
  EEA19452.1 293 YAYDDNKSLSPRNRQRLATIKSALLIYCALLGL 325
                 57999**********************988754 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.068
     DUF2975  55 nvrrLrriglaliaaalllaagivalallaelelapgvvllllgvafaslvigllvl 111
                   r++ + g++l++ al+l+ag+ +   l+    a  +v  +l  ++++l++g +++
  EEA19452.1 416 QLRHVSWTGHVLLTFALVLTAGAGVGIALRG-GWAAAIVGAILSTILTALAMGSCSW 471
                 6788888888888886665555444444444.2556777777777788888887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (499 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       745  (0.0415528); expected 358.6 (0.02)
Passed bias filter:                      403  (0.0224776); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.46
# Mc/sec: 3279.78
//
Query:       EEA19453.1  [L=860]
Description: extracellular developmental signal biosynthesis protein FluG [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      1e-59  202.3   0.0    2.8e-59  200.8   0.0    1.7  1  Gln-synt_C    Glutamine synthetase, catalytic domain
    1.7e-15   57.6   0.1    5.9e-15   55.8   0.0    1.9  2  Amidohydro_2  Amidohydrolase
  ------ inclusion threshold ------
       0.14   12.1   0.0        0.5   10.3   0.0    2.0  1  HTH_43        Winged helix-turn helix


Domain annotation for each model (and alignments):
>> Gln-synt_C  Glutamine synthetase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  200.8   0.0   4.7e-63   2.8e-59       2     335 ..     540     846 ..     539     860 .] 0.89

  Alignments for each domain:
  == domain 1  score: 200.8 bits;  conditional E-value: 4.7e-63
                 T-HHHHHHHHHHHHHHTTCEEEEEEEEEEEEESEECCCESSEEEEEEE.TB...B.TSS-TTBHCCCCCTCCHHHHHHHHHHHTT--EECCEEECCCTE CS
  Gln-synt_C   2 rdPRsvlkralarlaeeGltvvvgpElEFflfdkeedkeasksllevdseekgrpaekggyfsvapvdeaedlrreivealealgieveashhEvatgQ 100
                 ++PR +l+r ++ l+   ++v++g+E+E ++++++ d++      ++ +     ++++ + +  +  ++a ++++eiv++l+++ i++e++h+E+a+gQ
  EEA19453.1 540 GCPRMTLQRIVTALN--PIQVTFGFEIEVVILRRHIDGT-----WNPLT-----RNHSWSNMTSDIRQNALQFLEEIVTTLASIDIHIEQFHAESAPGQ 626
                 79*********9986..68999***********998866.....33332.....223334444455567899*************************** PP

                 EEEEE--EECHHHHHHHHHHHHHHHHHHHHTT-EEE-SSSSSTTS---BEEEEEEEEECTTEESSB-TTSGGGB-HHHHHHHHHHHHHHHHHHHHHS-S CS
  Gln-synt_C 101 vEinlkfadalkaaDnvvtfKrvvkevArkhgltatFmpKplegdnGsgmHvhlSlwdkdgknlfadeddeyalselarhfigGllkhakaltaltapt 199
                 +E  l +a++l+a D+++  ++++++vA+++g++at+ p+p++ ++G+++H h+S++     +   +e            f++G+l+   a+ta+  ++
  EEA19453.1 627 FEFILPPASPLEAIDTLLKARQTIQNVAEMNGYRATLYPRPYPFSAGTASHAHFSIS-----PTTEEE-----------PFLAGILARFSAITAFSLSQ 709
                 *********************************************************.....444444...........5******************* PP

                 CCHHHHCSSSTTS.SSBEEEESS-TTCSEEEE-TSGGCSTEEEECEBTTS-HHHHHHHHHHHHHHHHHTT---.-----S-SSSS-TTTH..TSS-B.- CS
  Gln-synt_C 200 vnSYkRlvpgyea.PvalawgarNRsallRipaskekakrvElRlpdasaNPYLalAallaAgldGienklep.gepvekdlyelspeer..kgiee.l 293
                   SY+R  +g +a + +++wg++NR+a +R +     a ++El+ +d+ aN YLa+AallaAg+ Gi + l++ +e++  d+ +ls +er  +gi++ +
  EEA19453.1 710 EVSYERVASGVWAgSEWVTWGTQNREAPIRKIS----AGHWELKQIDGLANMYLAMAALLAAGYLGIAHSLSLtHEDCPVDASTLSTAERqrLGITDqI 804
                 *************6789**************99....9*******************************99873588999999999999988777655* PP

                 -SSHHHHHHHHHCSHHHCCSS-HHHHHHHHHHHHHCHHHHHC CS
  Gln-synt_C 294 PasleeAlealeedellkevlgeevieaylalkraEleelee 335
                 P++le +l+aleed+ + ++lg  ++ +y+a+kraE ++l +
  EEA19453.1 805 PKTLEVSLRALEEDDDMCAILGAGFVIKYIAVKRAEANKLAA 846
                 ***************9*********************99854 PP

>> Amidohydro_2  Amidohydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0      0.35   2.1e+03     160     206 ..      16      61 ..       4      65 .. 0.80
   2 !   55.8   0.0   9.9e-19   5.9e-15     144     291 .]     259     408 ..     258     408 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.35
                   HHHHHHHHHHHHHCCHH..HHCTTSEEEESGGGTTTTCHHHHHHHHHHH CS
  Amidohydro_2 160 pqettraiqplllsgva..rkfPnlkivlaHgGgpserlraalellarr 206
                   p ++ +a+++l++++v+  +k+P l  + ++++g   +l++a++ l++r
    EEA19453.1  16 PVIDNHAHNLLAAENVLdyEKYP-LESITSEAAGE--ALKQAPYTLSHR 61 
                   56677899999999999777999.99999999999..999999998886 PP

  == domain 2  score: 55.8 bits;  conditional E-value: 9.9e-19
                   EEEEE....CHHHCHHHHHHHHHHHHHHHCCHHHHCTTSEEEESGGGTTTTCHHHHHHHHHHHHHCCEEECCGHHHSSEEECCHHCHHHHHHHHHHH CS
  Amidohydro_2 144 pvdihtGpspewlfggpqettraiqplllsgvarkfPnlkivlaHgGgpserlraalellarrpnvyvklsglytellyfdspladppalarlieav 240
                   p+++htG      +g+ ++++   +p +l  +++++ ++++vl H ++p  + r+a +l++ +pnvy++l+ +y++     s +a   +l++  e++
    EEA19453.1 259 PIQFHTG------LGDNDIDLVLANPAYLQPLIERYHDVDFVLLHSSYP--YTREAGYLASVYPNVYLDLGEVYSM----VSKDAELAILRQSMELT 343
                   89***99......************************************..*********************9998....788888889******** PP

                   -GGGEEEE--BTSTTSTSCTTHHHHCHHHHH..............SSHHHHHHHHTHHHHHHCTB CS
  Amidohydro_2 241 gpdrilfGsDyPhptleaepealalldlval..............lsdeerekilggNAarlygl 291
                   +  r+l+++D  + +++ +++  + +d +++                +e+ ++il +N  +ly+l
    EEA19453.1 344 PTSRLLWSTDGHFHPETYWLSNRQFRDTLDTvlvdhvkqgvltvsEAKEAAADILFNNSNKLYDL 408
                   **********7777777777777666666666666666699998888889999999999999986 PP

>> HTH_43  Winged helix-turn helix
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   8.3e-05       0.5      29      65 ..     538     577 ..     533     605 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 8.3e-05
                 HH---HHHHHHHHHGGGGGT-EEEEE--T...TS-S--EE CS
      HTH_43  29 ltgmPRRtlqDtlkalaeldielefvqeg...ernnaGyy 65 
                 l g PR tlq ++ al+ +++++ f+ e    +r+ +G++
  EEA19453.1 538 LEGCPRMTLQRIVTALNPIQVTFGFEIEVvilRRHIDGTW 577
                 6799*********************875422257777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (860 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       388  (0.0216409); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.67u 0.28s 00:00:00.95 Elapsed: 00:00:00.46
# Mc/sec: 5597.87
//
Query:       EEA19454.1  [L=1346]
Description: kinesin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   3.9e-130  420.8  20.7    9.7e-11   41.2   0.1   13.5 13  TPR_10        Tetratricopeptide repeat
   3.5e-125  408.5  56.6    1.8e-17   63.4   2.0    9.3  9  TPR_12        Tetratricopeptide repeat
    5.8e-72  234.8  51.6    9.9e-06   25.2   0.4   13.6 13  TPR_1         Tetratricopeptide repeat
    1.5e-51  168.3  44.2    0.00037   20.4   0.3   13.7 13  TPR_2         Tetratricopeptide repeat
    1.5e-45  149.9  41.5     0.0013   18.6   0.1   13.2 12  TPR_7         Tetratricopeptide repeat
    4.7e-39  134.7  15.5    3.7e-14   52.8   1.4    6.1  6  TPR_MalT      MalT-like TPR region
    4.4e-37  123.2  46.5      0.014   15.6   0.2   13.8 13  TPR_8         Tetratricopeptide repeat
    6.2e-37  126.0  49.0      0.011   16.4   0.7   14.2 14  TPR_16        Tetratricopeptide repeat
    6.4e-36  120.0  18.9       0.24   12.3   0.0   13.9 13  TPR_14        Tetratricopeptide repeat
    4.9e-23   79.8  30.5       0.52   10.8   0.2   15.0 13  TPR_17        Tetratricopeptide repeat
    5.8e-14   52.4  37.9     0.0056   17.2   0.6    9.0  7  TPR_19        Tetratricopeptide repeat
    8.4e-12   44.5   0.0         39    5.3   0.0   11.3 11  TPR_4         Tetratricopeptide repeat
    5.4e-11   42.2   0.2    1.2e-10   41.0   0.2    1.6  1  PNP_UDP_1     Phosphorylase superfamily
    9.2e-10   38.6  14.9        0.1   12.3   0.5    6.5  6  DUF2225       Uncharacterized protein conserved in bacteria (
    4.5e-09   35.8  60.7       0.11   12.2   0.1   12.4 12  TPR_11        TPR repeat
    7.2e-09   35.6  16.6        6.4    6.4   0.1   10.6 12  RPN7          26S proteasome subunit RPN7
    9.9e-09   34.9  12.3         34    5.0   0.0   11.9 12  PPR           PPR repeat
    2.9e-08   33.2   0.0    5.1e-08   32.4   0.0    1.3  1  NB-ARC        NB-ARC domain
    3.2e-07   30.2  52.9        1.9    8.2   0.1   12.5 10  TPR_21        Tetratricopeptide repeat-like domain
    3.5e-06   27.5   0.0    2.7e-05   24.6   0.0    2.4  2  AAA_16        AAA ATPase domain
    0.00028   20.6   0.0         34    4.1   0.0    6.4  6  Ribosomal_S7  Ribosomal protein S7p/S5e
    0.00043   20.3   0.0     0.0018   18.3   0.0    1.9  2  ATPase_2      ATPase domain predominantly from Archaea
    0.00092   19.6   0.8    4.9e+02    1.3   0.0    7.9  8  KIF1B         Kinesin protein 1B
      0.001   16.9   0.2        2.3    5.8   0.0    4.4  6  Strumpellin   Hereditary spastic paraplegia protein strumpell
     0.0036   17.6   0.0     0.0096   16.2   0.0    1.7  1  AAA_22        AAA domain
     0.0042   17.0   0.0      0.011   15.7   0.0    1.7  1  NACHT         NACHT domain
  ------ inclusion threshold ------
      0.011   16.3  67.6        5.3    7.9   0.5   13.6 13  TPR_6         Tetratricopeptide repeat
      0.018   14.1   7.4        3.6    6.6   0.0    6.0  7  GHL13         Hypothetical glycosyl hydrolase family 13
      0.029   14.5   0.0      0.073   13.2   0.0    1.7  1  AAA_33        AAA domain
      0.035   14.7   0.3         38    4.9   0.0    5.6  4  DUF5344       Family of unknown function (DUF5344)
      0.042   13.9   0.0       0.13   12.2   0.0    1.8  1  AAA_14        AAA domain
      0.052   14.1  36.9         43    4.7   0.1   11.4 12  DUF4810       Domain of unknown function (DUF4810)
      0.053   13.2   0.5       0.64    9.7   0.0    2.7  3  AAA_24        AAA domain
      0.063   12.8   0.1       0.51    9.8   0.0    2.4  2  CBP_BcsQ      Cellulose biosynthesis protein BcsQ
      0.082   13.2   0.0         81    3.6   0.0    5.3  2  DUF4388       Domain of unknown function (DUF4388)
       0.12   12.7   0.0       0.27   11.7   0.0    1.5  1  AAA           ATPase family associated with various cellular 
       0.16   12.8  12.0         65    4.4   0.0    6.1  4  DUF1754       Eukaryotic family of unknown function (DUF1754)
       0.18   11.2   0.0       0.92    8.9   0.0    2.2  1  TniB          Bacterial TniB protein
        0.3   11.2  41.7        3.8    7.7   0.2   11.5 12  MIT           MIT (microtubule interacting and transport) dom
       0.52   10.2   2.6        2.8    7.8   0.0    3.5  2  APS_kinase    Adenylylsulphate kinase
       0.66   10.0  35.3          9    6.4   0.1   11.1 12  TPR_3         Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.5   0.0   1.1e-09   4.7e-07       4      41 ..     760     797 ..     757     798 .. 0.95
   2 !   34.8   0.1   2.2e-11   9.8e-09       1      41 [.     799     839 ..     799     840 .. 0.95
   3 !   36.1   0.0     9e-12   3.9e-09       1      41 [.     841     881 ..     841     882 .. 0.96
   4 !   34.6   0.0   2.7e-11   1.2e-08       1      41 [.     883     923 ..     883     924 .. 0.96
   5 !   31.8   0.1     2e-10   8.7e-08       2      40 ..     926     964 ..     925     966 .. 0.94
   6 !   31.2   0.0   3.1e-10   1.4e-07       1      41 [.     967    1007 ..     967    1008 .. 0.96
   7 !   38.4   0.0   1.6e-12   7.2e-10       1      41 [.    1009    1049 ..    1009    1050 .. 0.96
   8 !   27.9   0.0   3.3e-09   1.5e-06       1      41 [.    1051    1091 ..    1051    1092 .. 0.95
   9 !   40.8   0.0     3e-13   1.3e-10       1      40 [.    1093    1132 ..    1093    1134 .. 0.96
  10 !   35.2   0.0   1.7e-11   7.3e-09       1      41 [.    1135    1175 ..    1135    1176 .. 0.94
  11 !   34.6   0.0   2.7e-11   1.2e-08       1      41 [.    1177    1217 ..    1177    1218 .. 0.96
  12 !   41.2   0.1   2.2e-13   9.7e-11       1      39 [.    1219    1257 ..    1219    1259 .. 0.95
  13 ?    6.1   0.0     0.024        11       9      39 ..    1273    1303 ..    1270    1303 .. 0.94

  Alignments for each domain:
  == domain 1  score: 29.5 bits;  conditional E-value: 1.1e-09
      TPR_10   4 slnNLanalrqrgrydeAealleealairrrllGpdHP 41 
                 +l+ ++++l++rg++ +Ae+++++al+ ++++ GpdH 
  EEA19454.1 760 ALHMMGILLSDRGNLGKAEKMYQRALEGYEKAWGPDHT 797
                 89***********************************6 PP

  == domain 2  score: 34.8 bits;  conditional E-value: 2.2e-11
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHP 41 
                 t+ + nNL+ ++ ++g++++Ae+++++al+ ++++ G +H 
  EEA19454.1 799 TLDTVNNLGLLYADQGKLTDAEKMYQRALEGYEKAWGSNHT 839
                 78899**********************************96 PP

  == domain 3  score: 36.1 bits;  conditional E-value: 9e-12
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHP 41 
                 t+ + nNL+n++ ++g++++Ae+++++al+  +++ GpdH 
  EEA19454.1 841 TLDTVNNLGNLYKNQGKLADAEKMYQRALEGKEKAWGPDHT 881
                 78899***********************************6 PP

  == domain 4  score: 34.6 bits;  conditional E-value: 2.7e-11
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHP 41 
                 t+ + nNL+ ++ ++g++ +Ae+++++al+ ++++ GpdH 
  EEA19454.1 883 TLDTVNNLGLLYADQGKLVDAEKMYQRALEGYEKAWGPDHT 923
                 78899***********************************6 PP

  == domain 5  score: 31.8 bits;  conditional E-value: 2e-10
      TPR_10   2 AsslnNLanalrqrgrydeAealleealairrrllGpdH 40 
                 +++ nNL+ ++ ++g++++Ae+++++al+  + + GpdH
  EEA19454.1 926 LNTVNNLGLLYADQGKLEDAEKMYQRALEGKETAWGPDH 964
                 6778*********************************** PP

  == domain 6  score: 31.2 bits;  conditional E-value: 3.1e-10
      TPR_10    1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHP 41  
                  t+ + nNL+ ++ ++g++ +Ae+++++al+  +++ GpdH 
  EEA19454.1  967 TLDTVNNLGLLYADQGKLVDAEKMYQRALEGKEKAWGPDHT 1007
                  78899***********************************6 PP

  == domain 7  score: 38.4 bits;  conditional E-value: 1.6e-12
      TPR_10    1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHP 41  
                  t+ + nNL+ +++++g++++Ae+++++al+ ++++ GpdH 
  EEA19454.1 1009 TLDTVNNLGLLYTNQGKLTDAEKMYQRALEGYEKAWGPDHT 1049
                  78899***********************************6 PP

  == domain 8  score: 27.9 bits;  conditional E-value: 3.3e-09
      TPR_10    1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHP 41  
                  t+ + nNL+ ++ ++g++ +Ae+++++al+   ++ Gp+H 
  EEA19454.1 1051 TLDTVNNLGLLYANQGKLVDAEKMYQQALEGKVKAWGPNHT 1091
                  78899**********************************96 PP

  == domain 9  score: 40.8 bits;  conditional E-value: 3e-13
      TPR_10    1 tAsslnNLanalrqrgrydeAealleealairrrllGpdH 40  
                  t+ + nNL+n++  +g++++Ae++++ al+ ++++lGpdH
  EEA19454.1 1093 TLDTVNNLGNLYAGQGKLTDAEKMYQLALEGYEKALGPDH 1132
                  78899*********************************** PP

  == domain 10  score: 35.2 bits;  conditional E-value: 1.7e-11
      TPR_10    1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHP 41  
                  t+ + nNL+n++ ++g++++Ae+++++al+   +++GpdH 
  EEA19454.1 1135 TLGIVNNLGNLYVDQGKLTDAEKMYQRALEGKVKACGPDHT 1175
                  56777***********************************6 PP

  == domain 11  score: 34.6 bits;  conditional E-value: 2.7e-11
      TPR_10    1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHP 41  
                  t+ + nNL+ ++ ++g++ +Ae+++++al+ ++++ GpdH 
  EEA19454.1 1177 TLDTVNNLGLLYADQGKLVDAEKMYQRALEGYEKAWGPDHT 1217
                  78899***********************************6 PP

  == domain 12  score: 41.2 bits;  conditional E-value: 2.2e-13
      TPR_10    1 tAsslnNLanalrqrgrydeAealleealairrrllGpd 39  
                  t+ + nNL+ ++ ++g++++Ae+l+++al+ ++++lGpd
  EEA19454.1 1219 TLDTVNNLGLLYADQGKLEDAEKLYQRALEGYEKALGPD 1257
                  78899*********************************9 PP

  == domain 13  score: 6.1 bits;  conditional E-value: 0.024
      TPR_10    9 analrqrgrydeAealleealairrrllGpd 39  
                  +++l + gr+ +A  ++ +al+ ++ ++G++
  EEA19454.1 1273 GMLLEDKGRLRDAKLMYTRALSGYKLVFGTN 1303
                  889999***********************97 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.5   0.5   1.4e-18   6.1e-16       4      77 .]     759     832 ..     756     832 .. 0.95
   2 !   60.8   0.4   2.7e-19   1.2e-16       5      77 .]     844     916 ..     840     916 .. 0.95
   3 !   60.2   1.3   3.9e-19   1.7e-16       7      76 ..     888     957 ..     886     958 .. 0.96
   4 !   59.6   0.7   6.3e-19   2.8e-16       4      77 .]     927    1000 ..     924    1000 .. 0.93
   5 !   58.1   0.1   1.8e-18   7.7e-16       5      73 ..    1012    1080 ..    1003    1082 .. 0.94
   6 !   58.5   0.3   1.3e-18   5.8e-16       5      73 ..    1096    1164 ..    1090    1166 .. 0.95
   7 !   60.9   0.2   2.5e-19   1.1e-16       7      77 .]    1140    1210 ..    1134    1210 .. 0.96
   8 !   63.4   2.0   4.1e-20   1.8e-17       5      77 .]    1180    1252 ..    1176    1252 .. 0.95
   9 !   36.5   3.0   9.8e-12   4.3e-09       5      76 ..    1222    1297 ..    1218    1298 .. 0.86

  Alignments for each domain:
  == domain 1  score: 58.5 bits;  conditional E-value: 1.4e-18
      TPR_12   4 talnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiaek 77 
                  al+ ++ +l  +g++ +A++++++ale ++++ Gpdh  t+ t +nLg ly  +g++ +A++++++al+ +ek
  EEA19454.1 759 YALHMMGILLSDRGNLGKAEKMYQRALEGYEKAWGPDHTSTLDTVNNLGLLYADQGKLTDAEKMYQRALEGYEK 832
                 578779************************9999*************************************996 PP

  == domain 2  score: 60.8 bits;  conditional E-value: 2.7e-19
      TPR_12   5 alnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiaek 77 
                 + nnl++++  +g++++A++++++ale  +++ Gpdh  t+ t +nLg ly  +g++ +A++++++al+ +ek
  EEA19454.1 844 TVNNLGNLYKNQGKLADAEKMYQRALEGKEKAWGPDHTSTLDTVNNLGLLYADQGKLVDAEKMYQRALEGYEK 916
                 4469*************************9999*************************************996 PP

  == domain 3  score: 60.2 bits;  conditional E-value: 3.9e-19
      TPR_12   7 nnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                 nnl+++++ +g++ +A++++++ale ++++ Gpdh   ++t +nLg ly  +g++e+A++++++al+ +e
  EEA19454.1 888 NNLGLLYADQGKLVDAEKMYQRALEGYEKAWGPDHTSILNTVNNLGLLYADQGKLEDAEKMYQRALEGKE 957
                 59*************************9999***********************************9776 PP

  == domain 4  score: 59.6 bits;  conditional E-value: 6.3e-19
      TPR_12    4 talnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiaek 77  
                  ++ nnl+++++ +g++++A++++++ale  + + Gpdh lt+ t +nLg ly  +g++ +A++++++al+ +ek
  EEA19454.1  927 NTVNNLGLLYADQGKLEDAEKMYQRALEGKETAWGPDHTLTLDTVNNLGLLYADQGKLVDAEKMYQRALEGKEK 1000
                  55569*************************8888************************************8875 PP

  == domain 5  score: 58.1 bits;  conditional E-value: 1.8e-18
      TPR_12    5 alnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleeala 73  
                  + nnl+++++ +g++++A++++++ale ++++ Gpdh  t+ t +nLg ly  +g++ +A++++++al+
  EEA19454.1 1012 TVNNLGLLYTNQGKLTDAEKMYQRALEGYEKAWGPDHTSTLDTVNNLGLLYANQGKLVDAEKMYQQALE 1080
                  4469*************************9999***********************************8 PP

  == domain 6  score: 58.5 bits;  conditional E-value: 1.3e-18
      TPR_12    5 alnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleeala 73  
                  + nnl+++++ +g++++A+++++ ale ++++lGpdh  t+ + +nLg ly  +g++ +A++++++al+
  EEA19454.1 1096 TVNNLGNLYAGQGKLTDAEKMYQLALEGYEKALGPDHISTLGIVNNLGNLYVDQGKLTDAEKMYQRALE 1164
                  4469****************************************************************8 PP

  == domain 7  score: 60.9 bits;  conditional E-value: 2.5e-19
      TPR_12    7 nnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiaek 77  
                  nnl++++  +g++++A++++++ale   ++ Gpdh  t+ t +nLg ly  +g++ +A++++++al+ +ek
  EEA19454.1 1140 NNLGNLYVDQGKLTDAEKMYQRALEGKVKACGPDHTSTLDTVNNLGLLYADQGKLVDAEKMYQRALEGYEK 1210
                  59******************************************************************996 PP

  == domain 8  score: 63.4 bits;  conditional E-value: 4.1e-20
      TPR_12    5 alnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiaek 77  
                  + nnl+++++ +g++ +A++++++ale ++++ Gpdh  t+ t +nLg ly  +g++e+A++l+++al+ +ek
  EEA19454.1 1180 TVNNLGLLYADQGKLVDAEKMYQRALEGYEKAWGPDHTSTLDTVNNLGLLYADQGKLEDAEKLYQRALEGYEK 1252
                  4469*************************9999*************************************996 PP

  == domain 9  score: 36.5 bits;  conditional E-value: 9.8e-12
      TPR_12    5 alnnlaavlrrlgrydeAlellekaleiarrllGpdh.pl...tattlrnLgrlyralgryeeAlelleealaiae 76  
                  + nnl+++++ +g++++A++l+++ale ++++lGpd+ +    +++  + +g+l++  gr+++A  ++++al  ++
  EEA19454.1 1222 TVNNLGLLYADQGKLEDAEKLYQRALEGYEKALGPDNiLSyvpALNNAYSYGMLLEDKGRLRDAKLMYTRALSGYK 1297
                  4469********************************944433346666779*********************9886 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.6   0.1    0.0001     0.046       2      29 ..     759     786 ..     758     786 .. 0.94
   2 !   22.6   0.1   1.5e-07   6.6e-05       5      29 ..     804     828 ..     801     828 .. 0.97
   3 !   25.2   0.4   2.3e-08   9.9e-06       5      29 ..     846     870 ..     843     870 .. 0.97
   4 !   21.7   0.1   2.7e-07   0.00012       5      29 ..     888     912 ..     885     912 .. 0.97
   5 !   24.9   0.3   2.8e-08   1.2e-05       5      29 ..     930     954 ..     928     954 .. 0.97
   6 !   21.7   0.1   2.7e-07   0.00012       5      29 ..     972     996 ..     969     996 .. 0.97
   7 !   23.2   0.1   9.5e-08   4.2e-05       5      29 ..    1014    1038 ..    1011    1038 .. 0.97
   8 !   21.8   0.2   2.6e-07   0.00011       5      29 ..    1056    1080 ..    1053    1080 .. 0.97
   9 !   18.5   0.2     3e-06    0.0013       5      29 ..    1098    1122 ..    1095    1122 .. 0.96
  10 !   22.1   0.2   2.1e-07   9.2e-05       5      29 ..    1140    1164 ..    1140    1164 .. 0.98
  11 !   21.7   0.1   2.7e-07   0.00012       5      29 ..    1182    1206 ..    1179    1206 .. 0.97
  12 !   25.0   0.4   2.6e-08   1.1e-05       5      29 ..    1224    1248 ..    1221    1248 .. 0.97
  13 ?    2.4   0.0      0.35   1.5e+02       8      28 ..    1273    1293 ..    1273    1294 .. 0.94

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 0.0001
                 HHHHHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1   2 kalynlGnayfklgkydeAleyyekALe 29 
                 +al  +G ++   g++ +A++ y++ALe
  EEA19454.1 759 YALHMMGILLSDRGNLGKAEKMYQRALE 786
                 688899*********************8 PP

  == domain 2  score: 22.6 bits;  conditional E-value: 1.5e-07
                 HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1   5 ynlGnayfklgkydeAleyyekALe 29 
                 +nlG++y  +gk+ +A++ y++ALe
  EEA19454.1 804 NNLGLLYADQGKLTDAEKMYQRALE 828
                 8***********************8 PP

  == domain 3  score: 25.2 bits;  conditional E-value: 2.3e-08
                 HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1   5 ynlGnayfklgkydeAleyyekALe 29 
                 +nlGn+y ++gk+ +A++ y++ALe
  EEA19454.1 846 NNLGNLYKNQGKLADAEKMYQRALE 870
                 8***********************8 PP

  == domain 4  score: 21.7 bits;  conditional E-value: 2.7e-07
                 HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1   5 ynlGnayfklgkydeAleyyekALe 29 
                 +nlG++y  +gk+ +A++ y++ALe
  EEA19454.1 888 NNLGLLYADQGKLVDAEKMYQRALE 912
                 8***********************8 PP

  == domain 5  score: 24.9 bits;  conditional E-value: 2.8e-08
                 HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1   5 ynlGnayfklgkydeAleyyekALe 29 
                 +nlG++y  +gk+++A++ y++ALe
  EEA19454.1 930 NNLGLLYADQGKLEDAEKMYQRALE 954
                 8***********************8 PP

  == domain 6  score: 21.7 bits;  conditional E-value: 2.7e-07
                 HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1   5 ynlGnayfklgkydeAleyyekALe 29 
                 +nlG++y  +gk+ +A++ y++ALe
  EEA19454.1 972 NNLGLLYADQGKLVDAEKMYQRALE 996
                 8***********************8 PP

  == domain 7  score: 23.2 bits;  conditional E-value: 9.5e-08
                  HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1    5 ynlGnayfklgkydeAleyyekALe 29  
                  +nlG++y ++gk+ +A++ y++ALe
  EEA19454.1 1014 NNLGLLYTNQGKLTDAEKMYQRALE 1038
                  8***********************8 PP

  == domain 8  score: 21.8 bits;  conditional E-value: 2.6e-07
                  HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1    5 ynlGnayfklgkydeAleyyekALe 29  
                  +nlG++y ++gk+ +A++ y++ALe
  EEA19454.1 1056 NNLGLLYANQGKLVDAEKMYQQALE 1080
                  8***********************8 PP

  == domain 9  score: 18.5 bits;  conditional E-value: 3e-06
                  HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1    5 ynlGnayfklgkydeAleyyekALe 29  
                  +nlGn+y  +gk+ +A++ y+ ALe
  EEA19454.1 1098 NNLGNLYAGQGKLTDAEKMYQLALE 1122
                  8**********************98 PP

  == domain 10  score: 22.1 bits;  conditional E-value: 2.1e-07
                  HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1    5 ynlGnayfklgkydeAleyyekALe 29  
                  +nlGn+y  +gk+ +A++ y++ALe
  EEA19454.1 1140 NNLGNLYVDQGKLTDAEKMYQRALE 1164
                  7***********************8 PP

  == domain 11  score: 21.7 bits;  conditional E-value: 2.7e-07
                  HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1    5 ynlGnayfklgkydeAleyyekALe 29  
                  +nlG++y  +gk+ +A++ y++ALe
  EEA19454.1 1182 NNLGLLYADQGKLVDAEKMYQRALE 1206
                  8***********************8 PP

  == domain 12  score: 25.0 bits;  conditional E-value: 2.6e-08
                  HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1    5 ynlGnayfklgkydeAleyyekALe 29  
                  +nlG++y  +gk+++A++ y++ALe
  EEA19454.1 1224 NNLGLLYADQGKLEDAEKLYQRALE 1248
                  8***********************8 PP

  == domain 13  score: 2.4 bits;  conditional E-value: 0.35
                  HHHHHHTT-HHHHHHHHHHHH CS
       TPR_1    8 GnayfklgkydeAleyyekAL 28  
                  G+++  +g++ +A   y +AL
  EEA19454.1 1273 GMLLEDKGRLRDAKLMYTRAL 1293
                  88999***************9 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.3   0.1   0.00033      0.14       2      29 ..     759     786 ..     758     786 .. 0.95
   2 !   15.8   0.1   2.5e-05     0.011       5      29 ..     804     828 ..     801     828 .. 0.95
   3 !   17.8   0.2   5.5e-06    0.0024       5      29 ..     846     870 ..     843     870 .. 0.95
   4 !   14.9   0.1   4.9e-05     0.021       5      29 ..     888     912 ..     885     912 .. 0.95
   5 !   18.0   0.2   4.9e-06    0.0022       5      29 ..     930     954 ..     928     954 .. 0.96
   6 !   14.9   0.1   4.9e-05     0.021       5      29 ..     972     996 ..     969     996 .. 0.95
   7 !   14.8   0.0   5.4e-05     0.024       5      29 ..    1014    1038 ..    1011    1038 .. 0.95
   8 !   15.7   0.1   2.6e-05     0.012       5      29 ..    1056    1080 ..    1053    1080 .. 0.95
   9 !   12.3   0.1   0.00032      0.14       5      29 ..    1098    1122 ..    1095    1122 .. 0.95
  10 !   15.1   0.0   4.3e-05     0.019       5      29 ..    1140    1164 ..    1138    1164 .. 0.96
  11 !   14.9   0.1   4.9e-05     0.021       5      29 ..    1182    1206 ..    1179    1206 .. 0.95
  12 !   20.4   0.3   8.5e-07   0.00037       5      29 ..    1224    1248 ..    1221    1248 .. 0.95
  13 ?    4.2   0.1      0.13        58       5      28 ..    1270    1293 ..    1268    1294 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00033
       TPR_2   2 ealynlGlayyklgdyeeAleafekAle 29 
                 +al+++G ++  +g++ +A++ +++Ale
  EEA19454.1 759 YALHMMGILLSDRGNLGKAEKMYQRALE 786
                 699***********************97 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 2.5e-05
       TPR_2   5 ynlGlayyklgdyeeAleafekAle 29 
                 +nlGl+y+ +g++ +A++ +++Ale
  EEA19454.1 804 NNLGLLYADQGKLTDAEKMYQRALE 828
                 79*********************97 PP

  == domain 3  score: 17.8 bits;  conditional E-value: 5.5e-06
       TPR_2   5 ynlGlayyklgdyeeAleafekAle 29 
                 +nlG++y ++g++++A++ +++Ale
  EEA19454.1 846 NNLGNLYKNQGKLADAEKMYQRALE 870
                 79*********************97 PP

  == domain 4  score: 14.9 bits;  conditional E-value: 4.9e-05
       TPR_2   5 ynlGlayyklgdyeeAleafekAle 29 
                 +nlGl+y+ +g++ +A++ +++Ale
  EEA19454.1 888 NNLGLLYADQGKLVDAEKMYQRALE 912
                 79*********************97 PP

  == domain 5  score: 18.0 bits;  conditional E-value: 4.9e-06
       TPR_2   5 ynlGlayyklgdyeeAleafekAle 29 
                 +nlGl+y+ +g++e+A++ +++Ale
  EEA19454.1 930 NNLGLLYADQGKLEDAEKMYQRALE 954
                 69*********************97 PP

  == domain 6  score: 14.9 bits;  conditional E-value: 4.9e-05
       TPR_2   5 ynlGlayyklgdyeeAleafekAle 29 
                 +nlGl+y+ +g++ +A++ +++Ale
  EEA19454.1 972 NNLGLLYADQGKLVDAEKMYQRALE 996
                 79*********************97 PP

  == domain 7  score: 14.8 bits;  conditional E-value: 5.4e-05
       TPR_2    5 ynlGlayyklgdyeeAleafekAle 29  
                  +nlGl+y ++g++ +A++ +++Ale
  EEA19454.1 1014 NNLGLLYTNQGKLTDAEKMYQRALE 1038
                  79*********************97 PP

  == domain 8  score: 15.7 bits;  conditional E-value: 2.6e-05
       TPR_2    5 ynlGlayyklgdyeeAleafekAle 29  
                  +nlGl+y+++g++ +A++ +++Ale
  EEA19454.1 1056 NNLGLLYANQGKLVDAEKMYQQALE 1080
                  79*********************97 PP

  == domain 9  score: 12.3 bits;  conditional E-value: 0.00032
       TPR_2    5 ynlGlayyklgdyeeAleafekAle 29  
                  +nlG++y+ +g++ +A++ ++ Ale
  EEA19454.1 1098 NNLGNLYAGQGKLTDAEKMYQLALE 1122
                  79*********************97 PP

  == domain 10  score: 15.1 bits;  conditional E-value: 4.3e-05
       TPR_2    5 ynlGlayyklgdyeeAleafekAle 29  
                  +nlG++y  +g++ +A++ +++Ale
  EEA19454.1 1140 NNLGNLYVDQGKLTDAEKMYQRALE 1164
                  79*********************97 PP

  == domain 11  score: 14.9 bits;  conditional E-value: 4.9e-05
       TPR_2    5 ynlGlayyklgdyeeAleafekAle 29  
                  +nlGl+y+ +g++ +A++ +++Ale
  EEA19454.1 1182 NNLGLLYADQGKLVDAEKMYQRALE 1206
                  79*********************97 PP

  == domain 12  score: 20.4 bits;  conditional E-value: 8.5e-07
       TPR_2    5 ynlGlayyklgdyeeAleafekAle 29  
                  +nlGl+y+ +g++e+A++++++Ale
  EEA19454.1 1224 NNLGLLYADQGKLEDAEKLYQRALE 1248
                  79*********************97 PP

  == domain 13  score: 4.2 bits;  conditional E-value: 0.13
       TPR_2    5 ynlGlayyklgdyeeAleafekAl 28  
                  y  G++++ +g++ +A+  + +Al
  EEA19454.1 1270 YSYGMLLEDKGRLRDAKLMYTRAL 1293
                  6689*******************9 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.1    0.0023         1       1      27 [.     760     786 ..     760     791 .. 0.91
   2 !   14.1   0.2   8.2e-05     0.036       3      27 ..     804     828 ..     802     833 .. 0.90
   3 !   17.0   0.1   9.4e-06    0.0041       3      28 ..     846     871 ..     844     875 .. 0.90
   4 !   12.7   0.2   0.00023       0.1       3      27 ..     888     912 ..     886     917 .. 0.90
   5 !   17.1   0.1   9.3e-06    0.0041       3      28 ..     930     955 ..     928     959 .. 0.90
   6 !   13.2   0.1   0.00015     0.067       3      28 ..     972     997 ..     970    1001 .. 0.90
   7 !   14.5   0.1     6e-05     0.026       3      27 ..    1014    1038 ..    1012    1043 .. 0.90
   8 !   13.7   0.0   0.00011     0.048       3      28 ..    1056    1081 ..    1054    1085 .. 0.90
   9 !   10.8   0.0   0.00091       0.4       3      28 ..    1098    1123 ..    1096    1131 .. 0.87
  10 !   17.0   0.0   9.9e-06    0.0043       3      28 ..    1140    1165 ..    1139    1169 .. 0.91
  11 !   12.7   0.2   0.00023       0.1       3      27 ..    1182    1206 ..    1180    1211 .. 0.90
  12 !   18.6   0.1     3e-06    0.0013       3      28 ..    1224    1249 ..    1222    1257 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0023
       TPR_7   1 aLlnLarlysrlGdyeeAielyeqsLa 27 
                 aL+ ++ l s++G+  +A++ y+++L+
  EEA19454.1 760 ALHMMGILLSDRGNLGKAEKMYQRALE 786
                 799*********************876 PP

  == domain 2  score: 14.1 bits;  conditional E-value: 8.2e-05
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLa 27 
                 +nL+ ly ++G+  +A++ y+++L+
  EEA19454.1 804 NNLGLLYADQGKLTDAEKMYQRALE 828
                 8*********************876 PP

  == domain 3  score: 17.0 bits;  conditional E-value: 9.4e-06
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLal 28 
                 +nL++ly ++G+ ++A++ y+++L+ 
  EEA19454.1 846 NNLGNLYKNQGKLADAEKMYQRALEG 871
                 8*********************8865 PP

  == domain 4  score: 12.7 bits;  conditional E-value: 0.00023
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLa 27 
                 +nL+ ly ++G+  +A++ y+++L+
  EEA19454.1 888 NNLGLLYADQGKLVDAEKMYQRALE 912
                 8*********************876 PP

  == domain 5  score: 17.1 bits;  conditional E-value: 9.3e-06
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLal 28 
                 +nL+ ly ++G+ e+A++ y+++L+ 
  EEA19454.1 930 NNLGLLYADQGKLEDAEKMYQRALEG 955
                 8*********************8875 PP

  == domain 6  score: 13.2 bits;  conditional E-value: 0.00015
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLal 28 
                 +nL+ ly ++G+  +A++ y+++L+ 
  EEA19454.1 972 NNLGLLYADQGKLVDAEKMYQRALEG 997
                 8*********************8865 PP

  == domain 7  score: 14.5 bits;  conditional E-value: 6e-05
       TPR_7    3 lnLarlysrlGdyeeAielyeqsLa 27  
                  +nL+ ly ++G+  +A++ y+++L+
  EEA19454.1 1014 NNLGLLYTNQGKLTDAEKMYQRALE 1038
                  8*********************876 PP

  == domain 8  score: 13.7 bits;  conditional E-value: 0.00011
       TPR_7    3 lnLarlysrlGdyeeAielyeqsLal 28  
                  +nL+ ly ++G+  +A++ y+q+L+ 
  EEA19454.1 1056 NNLGLLYANQGKLVDAEKMYQQALEG 1081
                  8*********************8865 PP

  == domain 9  score: 10.8 bits;  conditional E-value: 0.00091
       TPR_7    3 lnLarlysrlGdyeeAielyeqsLal 28  
                  +nL++ly  +G+  +A++ y+ +L+ 
  EEA19454.1 1098 NNLGNLYAGQGKLTDAEKMYQLALEG 1123
                  8*********************8865 PP

  == domain 10  score: 17.0 bits;  conditional E-value: 9.9e-06
       TPR_7    3 lnLarlysrlGdyeeAielyeqsLal 28  
                  +nL++ly+++G+  +A++ y+++L+ 
  EEA19454.1 1140 NNLGNLYVDQGKLTDAEKMYQRALEG 1165
                  7*********************8865 PP

  == domain 11  score: 12.7 bits;  conditional E-value: 0.00023
       TPR_7    3 lnLarlysrlGdyeeAielyeqsLa 27  
                  +nL+ ly ++G+  +A++ y+++L+
  EEA19454.1 1182 NNLGLLYADQGKLVDAEKMYQRALE 1206
                  8*********************876 PP

  == domain 12  score: 18.6 bits;  conditional E-value: 3e-06
       TPR_7    3 lnLarlysrlGdyeeAielyeqsLal 28  
                  +nL+ ly ++G+ e+A++ly+++L+ 
  EEA19454.1 1224 NNLGLLYADQGKLEDAEKLYQRALEG 1249
                  8*********************8865 PP

>> TPR_MalT  MalT-like TPR region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.9   1.3   7.9e-10   3.5e-07      79     188 ..     757     869 ..     699     871 .. 0.67
   2 !   38.6   0.9   1.8e-12   7.9e-10      45     187 ..     847     994 ..     845     994 .. 0.84
   3 !   36.4   1.9   8.4e-12   3.7e-09      46     188 ..     932    1079 ..     931    1080 .. 0.83
   4 !   52.8   1.4   8.5e-17   3.7e-14       9     187 ..    1018    1204 ..    1016    1206 .. 0.87
   5 !   22.1   0.0   1.9e-07   8.5e-05      80     161 ..    1178    1260 ..    1167    1267 .. 0.82
   6 ?    0.6   0.0      0.66   2.9e+02      79     108 ..    1265    1294 ..    1254    1298 .. 0.84

  Alignments for each domain:
  == domain 1  score: 29.9 bits;  conditional E-value: 7.9e-10
    TPR_MalT  79 allallqqaeilvaqGrLheAletyeqalqlateqglqqlplvgfllvlladllyEwndLeeAeqhlqeGie.lleql.ep.eaaldayvllarialaq 174
                 + +al   + +l  +G L +A+++y++al+ ++++ ++        +  l+ l+ ++++L+ Ae++ q+++e + + + ++   +ld    l  ++  q
  EEA19454.1 757 VSYALHMMGILLSDRGNLGKAEKMYQRALEGYEKAWGPDHTSTLDTVNNLGLLYADQGKLTDAEKMYQRALEgYEKAWgSNhTSTLDTVNNLGNLYKNQ 855
                 344444556677788888888888888888888888887777777777788888888888888888888888444446544233456777788888888 PP

    TPR_MalT 175 GdleeAetllekae 188
                 G+l +Ae++ ++a 
  EEA19454.1 856 GKLADAEKMYQRAL 869
                 88888888888774 PP

  == domain 2  score: 38.6 bits;  conditional E-value: 1.8e-12
    TPR_MalT  45 vlGeasllqGdleaAlqalqeaeklarqadsl.hv.allallqqaeilvaqGrLheAletyeqalqlateqglqqlplvgfllvlladllyEwndLeeA 141
                 +lG  +  qG+l++A++++q a +   +a  + h+ +l ++  ++ ++  qG+L +A+++y++al+ ++++ ++        +  l+ l+ ++++Le A
  EEA19454.1 847 NLGNLYKNQGKLADAEKMYQRALEGKEKAWGPdHTsTLDTVNNLGLLYADQGKLVDAEKMYQRALEGYEKAWGPDHTSILNTVNNLGLLYADQGKLEDA 945
                 68999999************888754333333244278888899***************************999877777777899************* PP

    TPR_MalT 142 eqhlqeGielleq.lepeaal..dayvllarialaqGdleeAetlleka 187
                 e++ q+++e  e  ++p+++l  d    l  +++ qG+l +Ae++ ++a
  EEA19454.1 946 EKMYQRALEGKETaWGPDHTLtlDTVNNLGLLYADQGKLVDAEKMYQRA 994
                 *********88874799888733566679999999*********99997 PP

  == domain 3  score: 36.4 bits;  conditional E-value: 8.4e-12
    TPR_MalT   46 lGeasllqGdleaAlqalqeaek...larqadslhvallallqqaeilvaqGrLheAletyeqalqlateqglqqlplvgfllvlladllyEwndLe 139 
                  lG  +  qG+le+A++++q a +   +a + d++  +l ++  ++ ++  qG+L +A+++y++al+  +++ ++        +  l+ l+  +++L+
  EEA19454.1  932 LGLLYADQGKLEDAEKMYQRALEgkeTAWGPDHT-LTLDTVNNLGLLYADQGKLVDAEKMYQRALEGKEKAWGPDHTSTLDTVNNLGLLYTNQGKLT 1027
                  78889999***********776521144444444.489999999************************999999988888999999*********** PP

    TPR_MalT  140 eAeqhlqeGie.lleqlepea..aldayvllarialaqGdleeAetllekae 188 
                   Ae++ q+++e + + ++p++  +ld    l  +++ qG+l +Ae++ ++a 
  EEA19454.1 1028 DAEKMYQRALEgYEKAWGPDHtsTLDTVNNLGLLYANQGKLVDAEKMYQQAL 1079
                  ***********55555888551145777889999999***********9985 PP

  == domain 4  score: 52.8 bits;  conditional E-value: 8.5e-17
    TPR_MalT    9 llaiasgdaeralelArqALallped...dllariaatavlGeasllqGdleaAlqalqeaek..larqadslhvallallqqaeilvaqGrLheAl 100 
                  ll++++g+ ++a+++ ++AL+  ++    d+ + + +  +lG  +  qG+l +A++++q+a +  +  +  + + +l ++  +++++  qG+L +A+
  EEA19454.1 1018 LLYTNQGKLTDAEKMYQRALEGYEKAwgpDHTSTLDTVNNLGLLYANQGKLVDAEKMYQQALEgkVKAWGPNHTSTLDTVNNLGNLYAGQGKLTDAE 1114
                  7899*****************9998655599999999**********************9996324455555555899999**************** PP

    TPR_MalT  101 etyeqalqlateqglqqlplvgfllvlladllyEwndLeeAeqhlqeGielleql.epea..aldayvllarialaqGdleeAetlleka 187 
                  ++y+ al+ ++++ ++       ++  l++l+ ++++L+ Ae++ q+++e   +  +p++  +ld    l  +++ qG+l +Ae++ ++a
  EEA19454.1 1115 KMYQLALEGYEKALGPDHISTLGIVNNLGNLYVDQGKLTDAEKMYQRALEGKVKAcGPDHtsTLDTVNNLGLLYADQGKLVDAEKMYQRA 1204
                  ****************988888899999**********************66665577541145777889999999***********998 PP

  == domain 5  score: 22.1 bits;  conditional E-value: 1.9e-07
    TPR_MalT   80 llallqqaeilvaqGrLheAletyeqalqlateqglqqlplvgfllvlladllyEwndLeeAeqhlqeGielleql.epeaal 161 
                  l ++  ++ ++  qG+L +A+++y++al+ ++++ ++        +  l+ l+ ++++Le Ae+  q+++e  e+  +p+ +l
  EEA19454.1 1178 LDTVNNLGLLYADQGKLVDAEKMYQRALEGYEKAWGPDHTSTLDTVNNLGLLYADQGKLEDAEKLYQRALEGYEKAlGPDNIL 1260
                  55556778899999999999999999999999999999888888999999999999999999999999999666644776655 PP

  == domain 6  score: 0.6 bits;  conditional E-value: 0.66
    TPR_MalT   79 allallqqaeilvaqGrLheAletyeqalq 108 
                  al   ++ +++l  +GrL++A  +y++al 
  EEA19454.1 1265 ALNNAYSYGMLLEDKGRLRDAKLMYTRALS 1294
                  556667889******************985 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.9   0.1    0.0043       1.9       3      29 ..     760     786 ..     758     786 .. 0.94
   2 !   13.3   0.1   0.00016     0.072       5      29 ..     804     828 ..     800     828 .. 0.93
   3 !   15.6   0.2   3.1e-05     0.014       5      29 ..     846     870 ..     842     873 .. 0.93
   4 !    8.8   0.1    0.0048       2.1       5      29 ..     888     912 ..     884     912 .. 0.93
   5 !   15.5   0.1   3.2e-05     0.014       5      29 ..     930     954 ..     927     955 .. 0.95
   6 !    8.9   0.1    0.0045         2       5      29 ..     972     996 ..     968     999 .. 0.93
   7 !   13.5   0.0   0.00014     0.062       5      29 ..    1014    1038 ..    1010    1038 .. 0.93
   8 !    9.8   0.1    0.0023      0.99       5      29 ..    1056    1080 ..    1052    1080 .. 0.93
   9 !   10.3   0.1    0.0015      0.67       5      29 ..    1098    1122 ..    1094    1122 .. 0.93
  10 !   13.6   0.0   0.00014     0.061       5      29 ..    1140    1164 ..    1137    1164 .. 0.95
  11 !    8.8   0.1    0.0048       2.1       5      29 ..    1182    1206 ..    1178    1206 .. 0.93
  12 !   15.1   0.2   4.6e-05      0.02       5      29 ..    1224    1248 ..    1220    1248 .. 0.93
  13 ?    5.5   0.2     0.055        24       5      29 ..    1270    1294 ..    1268    1294 .. 0.93

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0043
                 HHHHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAkeyyekale 29 
                 a++++g ++++ g++ +A++ y++ale
  EEA19454.1 760 ALHMMGILLSDRGNLGKAEKMYQRALE 786
                 799**********************97 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 0.00016
                 HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8   5 ynlgsiylklgdyeeAkeyyekale 29 
                 +nlg++y ++g++  A++ y++ale
  EEA19454.1 804 NNLGLLYADQGKLTDAEKMYQRALE 828
                 89*********************97 PP

  == domain 3  score: 15.6 bits;  conditional E-value: 3.1e-05
                 HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8   5 ynlgsiylklgdyeeAkeyyekale 29 
                 +nlg++y+++g++  A++ y++ale
  EEA19454.1 846 NNLGNLYKNQGKLADAEKMYQRALE 870
                 89*********************97 PP

  == domain 4  score: 8.8 bits;  conditional E-value: 0.0048
                 HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8   5 ynlgsiylklgdyeeAkeyyekale 29 
                 +nlg++y ++g++  A++ y++ale
  EEA19454.1 888 NNLGLLYADQGKLVDAEKMYQRALE 912
                 89*********************97 PP

  == domain 5  score: 15.5 bits;  conditional E-value: 3.2e-05
                 HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8   5 ynlgsiylklgdyeeAkeyyekale 29 
                 +nlg++y ++g++e A++ y++ale
  EEA19454.1 930 NNLGLLYADQGKLEDAEKMYQRALE 954
                 79*********************97 PP

  == domain 6  score: 8.9 bits;  conditional E-value: 0.0045
                 HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8   5 ynlgsiylklgdyeeAkeyyekale 29 
                 +nlg++y ++g++  A++ y++ale
  EEA19454.1 972 NNLGLLYADQGKLVDAEKMYQRALE 996
                 89*********************97 PP

  == domain 7  score: 13.5 bits;  conditional E-value: 0.00014
                  HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8    5 ynlgsiylklgdyeeAkeyyekale 29  
                  +nlg++y ++g++  A++ y++ale
  EEA19454.1 1014 NNLGLLYTNQGKLTDAEKMYQRALE 1038
                  89*********************97 PP

  == domain 8  score: 9.8 bits;  conditional E-value: 0.0023
                  HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8    5 ynlgsiylklgdyeeAkeyyekale 29  
                  +nlg++y ++g++  A++ y++ale
  EEA19454.1 1056 NNLGLLYANQGKLVDAEKMYQQALE 1080
                  89*********************97 PP

  == domain 9  score: 10.3 bits;  conditional E-value: 0.0015
                  HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8    5 ynlgsiylklgdyeeAkeyyekale 29  
                  +nlg++y  +g++  A++ y+ ale
  EEA19454.1 1098 NNLGNLYAGQGKLTDAEKMYQLALE 1122
                  89*********************97 PP

  == domain 10  score: 13.6 bits;  conditional E-value: 0.00014
                  HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8    5 ynlgsiylklgdyeeAkeyyekale 29  
                  +nlg++y ++g++  A++ y++ale
  EEA19454.1 1140 NNLGNLYVDQGKLTDAEKMYQRALE 1164
                  79*********************97 PP

  == domain 11  score: 8.8 bits;  conditional E-value: 0.0048
                  HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8    5 ynlgsiylklgdyeeAkeyyekale 29  
                  +nlg++y ++g++  A++ y++ale
  EEA19454.1 1182 NNLGLLYADQGKLVDAEKMYQRALE 1206
                  89*********************97 PP

  == domain 12  score: 15.1 bits;  conditional E-value: 4.6e-05
                  HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8    5 ynlgsiylklgdyeeAkeyyekale 29  
                  +nlg++y ++g++e A++ y++ale
  EEA19454.1 1224 NNLGLLYADQGKLEDAEKLYQRALE 1248
                  89*********************97 PP

  == domain 13  score: 5.5 bits;  conditional E-value: 0.055
                  HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8    5 ynlgsiylklgdyeeAkeyyekale 29  
                  y  g++++++g++  Ak  y +al+
  EEA19454.1 1270 YSYGMLLEDKGRLRDAKLMYTRALS 1294
                  678********************96 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.2       8.3   3.6e+03      20      50 ..     602     627 ..     601     628 .. 0.79
   2 ?    6.3   0.0     0.036        16       2      27 ..     763     788 ..     762     792 .. 0.87
   3 !   15.6   0.2   4.4e-05     0.019       2      27 ..     805     830 ..     804     834 .. 0.91
   4 !   12.5   0.1   0.00041      0.18       2      25 ..     847     870 ..     846     874 .. 0.93
   5 !   12.8   0.2   0.00033      0.15       2      27 ..     889     914 ..     888     918 .. 0.90
   6 !   15.3   0.2   5.6e-05     0.024       2      25 ..     931     954 ..     930     957 .. 0.93
   7 !   12.0   0.1   0.00058      0.25       2      25 ..     973     996 ..     972    1000 .. 0.93
   8 !   11.3   0.0   0.00095      0.42       2      27 ..    1015    1040 ..    1014    1044 .. 0.88
   9 !   10.7   0.1    0.0014      0.63       2      25 ..    1057    1080 ..    1056    1082 .. 0.93
  10 !    8.5   0.1    0.0073       3.2       2      25 ..    1099    1122 ..    1098    1128 .. 0.85
  11 !   16.3   0.0   2.6e-05     0.011       2      25 ..    1141    1164 ..    1140    1166 .. 0.94
  12 !   12.8   0.2   0.00033      0.15       2      27 ..    1183    1208 ..    1182    1212 .. 0.90
  13 !   16.4   0.7   2.4e-05     0.011       2      27 ..    1225    1250 ..    1224    1254 .. 0.89
  14 ?    0.7   0.0       1.9   8.5e+02       4      25 ..    1273    1294 ..    1270    1298 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 8.3
      TPR_16  20 leaalkrdpssPdaaeAllllgdaalrqgrl 50 
                 ++a +++d      a+A lll +a+l ++ l
  EEA19454.1 602 YNAIRAKD-----EAAANLLLLWAHLDHKTL 627
                 56666666.....99*********9988765 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.036
      TPR_16   2 alaraalragdyddAaaaleaalkrd 27 
                 +++ ++ ++g+  +A++++++al+ +
  EEA19454.1 763 MMGILLSDRGNLGKAEKMYQRALEGY 788
                 6788999***************9865 PP

  == domain 3  score: 15.6 bits;  conditional E-value: 4.4e-05
      TPR_16   2 alaraalragdyddAaaaleaalkrd 27 
                 +l+++++++g+ +dA++++++al+ +
  EEA19454.1 805 NLGLLYADQGKLTDAEKMYQRALEGY 830
                 689********************865 PP

  == domain 4  score: 12.5 bits;  conditional E-value: 0.00041
      TPR_16   2 alaraalragdyddAaaaleaalk 25 
                 +l++++ ++g+ +dA++++++al+
  EEA19454.1 847 NLGNLYKNQGKLADAEKMYQRALE 870
                 689*******************97 PP

  == domain 5  score: 12.8 bits;  conditional E-value: 0.00033
      TPR_16   2 alaraalragdyddAaaaleaalkrd 27 
                 +l+++++++g+  dA++++++al+ +
  EEA19454.1 889 NLGLLYADQGKLVDAEKMYQRALEGY 914
                 6899******************9865 PP

  == domain 6  score: 15.3 bits;  conditional E-value: 5.6e-05
      TPR_16   2 alaraalragdyddAaaaleaalk 25 
                 +l+++++++g+ +dA++++++al+
  EEA19454.1 931 NLGLLYADQGKLEDAEKMYQRALE 954
                 689*******************96 PP

  == domain 7  score: 12.0 bits;  conditional E-value: 0.00058
      TPR_16   2 alaraalragdyddAaaaleaalk 25 
                 +l+++++++g+  dA++++++al+
  EEA19454.1 973 NLGLLYADQGKLVDAEKMYQRALE 996
                 6899******************97 PP

  == domain 8  score: 11.3 bits;  conditional E-value: 0.00095
      TPR_16    2 alaraalragdyddAaaaleaalkrd 27  
                  +l++++ ++g+ +dA++++++al+ +
  EEA19454.1 1015 NLGLLYTNQGKLTDAEKMYQRALEGY 1040
                  6899999***************9865 PP

  == domain 9  score: 10.7 bits;  conditional E-value: 0.0014
      TPR_16    2 alaraalragdyddAaaaleaalk 25  
                  +l+++++++g+  dA++++++al+
  EEA19454.1 1057 NLGLLYANQGKLVDAEKMYQQALE 1080
                  689*******************96 PP

  == domain 10  score: 8.5 bits;  conditional E-value: 0.0073
      TPR_16    2 alaraalragdyddAaaaleaalk 25  
                  +l+++++ +g+ +dA+++++ al+
  EEA19454.1 1099 NLGNLYAGQGKLTDAEKMYQLALE 1122
                  68999************9987776 PP

  == domain 11  score: 16.3 bits;  conditional E-value: 2.6e-05
      TPR_16    2 alaraalragdyddAaaaleaalk 25  
                  +l+++++++g+ +dA++++++al+
  EEA19454.1 1141 NLGNLYVDQGKLTDAEKMYQRALE 1164
                  69********************96 PP

  == domain 12  score: 12.8 bits;  conditional E-value: 0.00033
      TPR_16    2 alaraalragdyddAaaaleaalkrd 27  
                  +l+++++++g+  dA++++++al+ +
  EEA19454.1 1183 NLGLLYADQGKLVDAEKMYQRALEGY 1208
                  6899******************9865 PP

  == domain 13  score: 16.4 bits;  conditional E-value: 2.4e-05
      TPR_16    2 alaraalragdyddAaaaleaalkrd 27  
                  +l+++++++g+ +dA++++++al+ +
  EEA19454.1 1225 NLGLLYADQGKLEDAEKLYQRALEGY 1250
                  68999*****************9865 PP

  == domain 14  score: 0.7 bits;  conditional E-value: 1.9
      TPR_16    4 araalragdyddAaaaleaalk 25  
                  ++++ + g+ +dA  ++++al 
  EEA19454.1 1273 GMLLEDKGRLRDAKLMYTRALS 1294
                  6788999**********99985 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.3   0.0   0.00054      0.24       3      31 ..     760     788 ..     759     796 .. 0.87
   2 !   10.5   0.0    0.0021       0.9       7      31 ..     806     830 ..     804     836 .. 0.86
   3 !   11.6   0.0   0.00094      0.41       7      29 ..     848     870 ..     846     880 .. 0.88
   4 ?    8.2   0.0     0.012       5.1       7      31 ..     890     914 ..     888     922 .. 0.86
   5 !   11.5   0.0     0.001      0.44       7      29 ..     932     954 ..     930     967 .. 0.86
   6 ?    7.6   0.0     0.017       7.6       7      29 ..     974     996 ..     973    1006 .. 0.87
   7 !   10.6   0.0     0.002      0.88       7      31 ..    1016    1040 ..    1015    1048 .. 0.85
   8 ?    6.8   0.0     0.032        14       7      29 ..    1058    1080 ..    1056    1088 .. 0.90
   9 ?    5.9   0.0     0.062        27       7      30 ..    1100    1128 ..    1098    1136 .. 0.81
  10 !    9.7   0.0    0.0037       1.6       7      29 ..    1142    1164 ..    1141    1176 .. 0.89
  11 ?    8.2   0.0     0.012       5.1       7      31 ..    1184    1208 ..    1182    1216 .. 0.86
  12 !   11.8   0.1   0.00079      0.34       7      30 ..    1226    1254 ..    1224    1262 .. 0.82
  13 ?    0.8   0.0       2.6   1.2e+03       5      29 ..    1270    1294 ..    1267    1300 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00054
      TPR_14   3 allalaeallalGdpdeAiallrralala 31 
                 al +++ +l  +G++ +A+++++ral+ +
  EEA19454.1 760 ALHMMGILLSDRGNLGKAEKMYQRALEGY 788
                 67899********************9854 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.0021
      TPR_14   7 laeallalGdpdeAiallrralala 31 
                 l+ +++ +G++ +A+++++ral+ +
  EEA19454.1 806 LGLLYADQGKLTDAEKMYQRALEGY 830
                 67899****************9854 PP

  == domain 3  score: 11.6 bits;  conditional E-value: 0.00094
      TPR_14   7 laeallalGdpdeAiallrrala 29 
                 l+ ++ ++G++++A+++++ral+
  EEA19454.1 848 LGNLYKNQGKLADAEKMYQRALE 870
                 7899*****************98 PP

  == domain 4  score: 8.2 bits;  conditional E-value: 0.012
      TPR_14   7 laeallalGdpdeAiallrralala 31 
                 l+ +++ +G++ +A+++++ral+ +
  EEA19454.1 890 LGLLYADQGKLVDAEKMYQRALEGY 914
                 67899****************9854 PP

  == domain 5  score: 11.5 bits;  conditional E-value: 0.001
      TPR_14   7 laeallalGdpdeAiallrrala 29 
                 l+ +++ +G++++A+++++ral+
  EEA19454.1 932 LGLLYADQGKLEDAEKMYQRALE 954
                 67899****************98 PP

  == domain 6  score: 7.6 bits;  conditional E-value: 0.017
      TPR_14   7 laeallalGdpdeAiallrrala 29 
                 l+ +++ +G++ +A+++++ral+
  EEA19454.1 974 LGLLYADQGKLVDAEKMYQRALE 996
                 67899****************98 PP

  == domain 7  score: 10.6 bits;  conditional E-value: 0.002
      TPR_14    7 laeallalGdpdeAiallrralala 31  
                  l+ ++ ++G++ +A+++++ral+ +
  EEA19454.1 1016 LGLLYTNQGKLTDAEKMYQRALEGY 1040
                  67899****************9854 PP

  == domain 8  score: 6.8 bits;  conditional E-value: 0.032
      TPR_14    7 laeallalGdpdeAiallrrala 29  
                  l+ +++++G++ +A++++++al+
  EEA19454.1 1058 LGLLYANQGKLVDAEKMYQQALE 1080
                  6789*****************97 PP

  == domain 9  score: 5.9 bits;  conditional E-value: 0.062
      TPR_14    7 laeallalGdpdeAiallrrala.....l 30  
                  l+ +++ +G++ +A+++++ al+     l
  EEA19454.1 1100 LGNLYAGQGKLTDAEKMYQLALEgyekaL 1128
                  788999***************99444444 PP

  == domain 10  score: 9.7 bits;  conditional E-value: 0.0037
      TPR_14    7 laeallalGdpdeAiallrrala 29  
                  l+ ++  +G++ +A+++++ral+
  EEA19454.1 1142 LGNLYVDQGKLTDAEKMYQRALE 1164
                  7899*****************98 PP

  == domain 11  score: 8.2 bits;  conditional E-value: 0.012
      TPR_14    7 laeallalGdpdeAiallrralala 31  
                  l+ +++ +G++ +A+++++ral+ +
  EEA19454.1 1184 LGLLYADQGKLVDAEKMYQRALEGY 1208
                  67899****************9854 PP

  == domain 12  score: 11.8 bits;  conditional E-value: 0.00079
      TPR_14    7 laeallalGdpdeAiallrrala.....l 30  
                  l+ +++ +G++++A++l++ral+     l
  EEA19454.1 1226 LGLLYADQGKLEDAEKLYQRALEgyekaL 1254
                  67899*****************9555444 PP

  == domain 13  score: 0.8 bits;  conditional E-value: 2.6
      TPR_14    5 lalaeallalGdpdeAiallrrala 29  
                  + ++ +l+  G++++A  ++ ral+
  EEA19454.1 1270 YSYGMLLEDKGRLRDAKLMYTRALS 1294
                  5688899****************97 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0     0.055        24      13      34 .]     758     779 ..     751     779 .. 0.89
   2 ?    6.9   0.0      0.02       8.9       2      34 .]     781     821 ..     780     821 .. 0.72
   3 !   10.8   0.2    0.0012      0.52      14      34 .]     843     863 ..     822     863 .. 0.77
   4 ?    7.1   0.0     0.019       8.2      13      34 .]     884     905 ..     864     905 .. 0.73
   5 !    8.2   0.1    0.0081       3.6      13      34 .]     926     947 ..     906     947 .. 0.71
   6 ?    6.9   0.0      0.02       8.9      14      34 .]     969     989 ..     948     989 .. 0.74
   7 ?    6.3   0.0     0.034        15      13      34 .]    1010    1031 ..     990    1031 .. 0.73
   8 !    9.2   0.1     0.004       1.7       2      34 .]    1033    1073 ..    1032    1073 .. 0.72
   9 ?    5.9   0.0     0.044        19      13      34 .]    1094    1115 ..    1074    1115 .. 0.73
  10 ?    4.1   0.0      0.16        71      17      34 .]    1140    1157 ..    1138    1157 .. 0.92
  11 ?    7.0   0.0     0.019       8.3      13      34 .]    1178    1199 ..    1158    1199 .. 0.74
  12 !    8.6   0.1    0.0058       2.6       2      34 .]    1201    1241 ..    1200    1241 .. 0.73
  13 ?    1.2   0.2       1.4   6.1e+02       2      32 ..    1243    1285 ..    1242    1286 .. 0.63

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.055
      TPR_17  13 adaynnLAelllknGdlmtArq 34 
                 ++a+++++ ll+ +G+l++A++
  EEA19454.1 758 SYALHMMGILLSDRGNLGKAEK 779
                 789*****************85 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.02
      TPR_17   2 ylkaleld.....Pnn...adaynnLAelllknGdlmtArq 34 
                 y++ale +     P++    d  nnL+ l++ +G+l +A++
  EEA19454.1 781 YQRALEGYekawgPDHtstLDTVNNLGLLYADQGKLTDAEK 821
                 66666665444455555566788*************99985 PP

  == domain 3  score: 10.8 bits;  conditional E-value: 0.0012
      TPR_17  14 daynnLAelllknGdlmtArq 34 
                 d  nnL++l++++G+l++A++
  EEA19454.1 843 DTVNNLGNLYKNQGKLADAEK 863
                 6779***************85 PP

  == domain 4  score: 7.1 bits;  conditional E-value: 0.019
      TPR_17  13 adaynnLAelllknGdlmtArq 34 
                  d  nnL+ l++ +G+l +A++
  EEA19454.1 884 LDTVNNLGLLYADQGKLVDAEK 905
                 56779**************985 PP

  == domain 5  score: 8.2 bits;  conditional E-value: 0.0081
      TPR_17  13 adaynnLAelllknGdlmtArq 34 
                  +  nnL+ l++ +G+l++A++
  EEA19454.1 926 LNTVNNLGLLYADQGKLEDAEK 947
                 66779***************85 PP

  == domain 6  score: 6.9 bits;  conditional E-value: 0.02
      TPR_17  14 daynnLAelllknGdlmtArq 34 
                 d  nnL+ l++ +G+l +A++
  EEA19454.1 969 DTVNNLGLLYADQGKLVDAEK 989
                 6779**************985 PP

  == domain 7  score: 6.3 bits;  conditional E-value: 0.034
      TPR_17   13 adaynnLAelllknGdlmtArq 34  
                   d  nnL+ l+ ++G+l +A++
  EEA19454.1 1010 LDTVNNLGLLYTNQGKLTDAEK 1031
                  56779************99985 PP

  == domain 8  score: 9.2 bits;  conditional E-value: 0.004
      TPR_17    2 ylkaleld.....Pnn...adaynnLAelllknGdlmtArq 34  
                  y++ale +     P++    d  nnL+ l++++G+l +A++
  EEA19454.1 1033 YQRALEGYekawgPDHtstLDTVNNLGLLYANQGKLVDAEK 1073
                  66666665444455555566788***************985 PP

  == domain 9  score: 5.9 bits;  conditional E-value: 0.044
      TPR_17   13 adaynnLAelllknGdlmtArq 34  
                   d  nnL++l++ +G+l +A++
  EEA19454.1 1094 LDTVNNLGNLYAGQGKLTDAEK 1115
                  57789************99985 PP

  == domain 10  score: 4.1 bits;  conditional E-value: 0.16
      TPR_17   17 nnLAelllknGdlmtArq 34  
                  nnL++l+  +G+l +A++
  EEA19454.1 1140 NNLGNLYVDQGKLTDAEK 1157
                  8************99985 PP

  == domain 11  score: 7.0 bits;  conditional E-value: 0.019
      TPR_17   13 adaynnLAelllknGdlmtArq 34  
                   d  nnL+ l++ +G+l +A++
  EEA19454.1 1178 LDTVNNLGLLYADQGKLVDAEK 1199
                  56779**************985 PP

  == domain 12  score: 8.6 bits;  conditional E-value: 0.0058
      TPR_17    2 ylkaleld.....Pnn...adaynnLAelllknGdlmtArq 34  
                  y++ale +     P++    d  nnL+ l++ +G+l++A++
  EEA19454.1 1201 YQRALEGYekawgPDHtstLDTVNNLGLLYADQGKLEDAEK 1241
                  66666665444455555566788****************85 PP

  == domain 13  score: 1.2 bits;  conditional E-value: 1.4
      TPR_17    2 ylkaleld.....Pnn.......adaynnLAelllknGdlmtA 32  
                  y++ale +     P+n        +  + ++ ll+ +G+l++A
  EEA19454.1 1243 YQRALEGYekalgPDNilsyvpaLNNAYSYGMLLEDKGRLRDA 1285
                  6666666555555666555544455677888888888888887 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0      0.37   1.6e+02      32      53 ..     765     786 ..     733     795 .. 0.65
   2 !   17.2   0.6   1.3e-05    0.0056       3      53 ..     812     870 ..     810     875 .. 0.89
   3 !   12.1   0.6    0.0005      0.22       3      53 ..     896     954 ..     894     959 .. 0.85
   4 !   11.8   0.3    0.0006      0.26       3      53 ..     980    1038 ..     978    1044 .. 0.87
   5 !    9.5   0.6    0.0031       1.4       4      53 ..    1065    1122 ..    1062    1127 .. 0.85
   6 !   12.7   0.8   0.00031      0.13       3      53 ..    1106    1164 ..    1104    1169 .. 0.89
   7 !   11.8   1.7   0.00062      0.27       3      53 ..    1190    1248 ..    1188    1255 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.37
      TPR_19  32 AeallalgqldeAealLdalpe 53 
                  ++l   g+l +Ae++ ++++e
  EEA19454.1 765 GILLSDRGNLGKAEKMYQRALE 786
                 6666666666666666666554 PP

  == domain 2  score: 17.2 bits;  conditional E-value: 1.3e-05
      TPR_19   3 aegdyaeAlalleqalqedpk........naearllLAeallalgqldeAealLdalpe 53 
                 ++g++++A +++++al+ + k         ++   +L +++ ++g l++Ae++ ++++e
  EEA19454.1 812 DQGKLTDAEKMYQRALEGYEKawgsnhtsTLDTVNNLGNLYKNQGKLADAEKMYQRALE 870
                 89**************9977777777788999999********************9987 PP

  == domain 3  score: 12.1 bits;  conditional E-value: 0.0005
      TPR_19   3 aegdyaeAlalleqalqe.....dpknaearl...lLAeallalgqldeAealLdalpe 53 
                 ++g++ +A +++++al+       p++  ++    +L  ++  +g l++Ae++ ++++e
  EEA19454.1 896 DQGKLVDAEKMYQRALEGyekawGPDHTSILNtvnNLGLLYADQGKLEDAEKMYQRALE 954
                 89**************884444466688777777799*****************99986 PP

  == domain 4  score: 11.8 bits;  conditional E-value: 0.0006
      TPR_19    3 aegdyaeAlalleqalqedpk........naearllLAeallalgqldeAealLdalpe 53  
                  ++g++ +A +++++al+ + k         ++   +L  ++ ++g l++Ae++ ++++e
  EEA19454.1  980 DQGKLVDAEKMYQRALEGKEKawgpdhtsTLDTVNNLGLLYTNQGKLTDAEKMYQRALE 1038
                  89**************9855556666888999999********************9987 PP

  == domain 5  score: 9.5 bits;  conditional E-value: 0.0031
      TPR_19    4 egdyaeAlalleqalqe.....dpk...naearllLAeallalgqldeAealLdalpe 53  
                  +g++ +A ++++qal+       p+    ++   +L +++  +g l++Ae++ + ++e
  EEA19454.1 1065 QGKLVDAEKMYQQALEGkvkawGPNhtsTLDTVNNLGNLYAGQGKLTDAEKMYQLALE 1122
                  89*************8855555444777999999*****************9887765 PP

  == domain 6  score: 12.7 bits;  conditional E-value: 0.00031
      TPR_19    3 aegdyaeAlalleqalqedpk........naearllLAeallalgqldeAealLdalpe 53  
                   +g++++A ++++ al+ + k         + +  +L ++++ +g l++Ae++ ++++e
  EEA19454.1 1106 GQGKLTDAEKMYQLALEGYEKalgpdhisTLGIVNNLGNLYVDQGKLTDAEKMYQRALE 1164
                  69**************9977777777999999999*******************99987 PP

  == domain 7  score: 11.8 bits;  conditional E-value: 0.00062
      TPR_19    3 aegdyaeAlalleqalqedpk........naearllLAeallalgqldeAealLdalpe 53  
                  ++g++ +A +++++al+ + k         ++   +L  ++  +g l++Ae+l ++++e
  EEA19454.1 1190 DQGKLVDAEKMYQRALEGYEKawgpdhtsTLDTVNNLGLLYADQGKLEDAEKLYQRALE 1248
                  89**************9977777777888999999********************9987 PP

>> TPR_4  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.0      0.59   2.6e+02       2      21 ..     759     778 ..     758     783 .. 0.87
   2 ?    1.9   0.0       1.1   4.9e+02       6      21 ..     805     820 ..     803     825 .. 0.87
   3 ?   -0.7   0.0       7.4   3.2e+03       6      21 ..     847     862 ..     846     867 .. 0.85
   4 ?    2.8   0.0      0.57   2.5e+02       6      21 ..     889     904 ..     887     909 .. 0.87
   5 ?    5.1   0.0     0.099        43       6      21 ..     931     946 ..     928     951 .. 0.87
   6 ?    2.8   0.0      0.57   2.5e+02       6      21 ..     973     988 ..     971     993 .. 0.87
   7 ?    1.2   0.0       1.9   8.3e+02       6      21 ..    1057    1072 ..    1055    1077 .. 0.87
   8 ?    0.1   0.0       4.2   1.8e+03       6      21 ..    1099    1114 ..    1097    1117 .. 0.91
   9 ?   -0.3   0.0       5.6   2.5e+03       6      21 ..    1141    1156 ..    1140    1161 .. 0.86
  10 ?    2.8   0.0      0.57   2.5e+02       6      21 ..    1183    1198 ..    1181    1203 .. 0.87
  11 ?    5.3   0.0     0.089        39       6      23 ..    1225    1242 ..    1223    1245 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.59
       TPR_4   2 rallaLArallalGdldeAr 21 
                 +al++++ +l ++G+l  A+
  EEA19454.1 759 YALHMMGILLSDRGNLGKAE 778
                 5899*************998 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 1.1
       TPR_4   6 aLArallalGdldeAr 21 
                 +L+ +++++G l +A+
  EEA19454.1 805 NLGLLYADQGKLTDAE 820
                 79**********9998 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 7.4
       TPR_4   6 aLArallalGdldeAr 21 
                 +L+ ++  +G l++A+
  EEA19454.1 847 NLGNLYKNQGKLADAE 862
                 79999999*******8 PP

  == domain 4  score: 2.8 bits;  conditional E-value: 0.57
       TPR_4   6 aLArallalGdldeAr 21 
                 +L+ +++++G l +A+
  EEA19454.1 889 NLGLLYADQGKLVDAE 904
                 79************98 PP

  == domain 5  score: 5.1 bits;  conditional E-value: 0.099
       TPR_4   6 aLArallalGdldeAr 21 
                 +L+ +++++G l++A+
  EEA19454.1 931 NLGLLYADQGKLEDAE 946
                 89*************8 PP

  == domain 6  score: 2.8 bits;  conditional E-value: 0.57
       TPR_4   6 aLArallalGdldeAr 21 
                 +L+ +++++G l +A+
  EEA19454.1 973 NLGLLYADQGKLVDAE 988
                 79************98 PP

  == domain 7  score: 1.2 bits;  conditional E-value: 1.9
       TPR_4    6 aLArallalGdldeAr 21  
                  +L+ +++ +G l +A+
  EEA19454.1 1057 NLGLLYANQGKLVDAE 1072
                  79************98 PP

  == domain 8  score: 0.1 bits;  conditional E-value: 4.2
       TPR_4    6 aLArallalGdldeAr 21  
                  +L+ +++ +G l +A+
  EEA19454.1 1099 NLGNLYAGQGKLTDAE 1114
                  79*********99997 PP

  == domain 9  score: -0.3 bits;  conditional E-value: 5.6
       TPR_4    6 aLArallalGdldeAr 21  
                  +L+ ++ ++G l +A+
  EEA19454.1 1141 NLGNLYVDQGKLTDAE 1156
                  799*********9998 PP

  == domain 10  score: 2.8 bits;  conditional E-value: 0.57
       TPR_4    6 aLArallalGdldeAr 21  
                  +L+ +++++G l +A+
  EEA19454.1 1183 NLGLLYADQGKLVDAE 1198
                  79************98 PP

  == domain 11  score: 5.3 bits;  conditional E-value: 0.089
       TPR_4    6 aLArallalGdldeAral 23  
                  +L+ +++++G l++A+ l
  EEA19454.1 1225 NLGLLYADQGKLEDAEKL 1242
                  79*************965 PP

>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.0   0.2   2.8e-13   1.2e-10       3     233 ..      14     302 ..      12     305 .. 0.83

  Alignments for each domain:
  == domain 1  score: 41.0 bits;  conditional E-value: 2.8e-13
                 EEEESSHHHHHHHHHHEEEEEEEEEE....TTEEEEEEEETTEEEEEEE--...SSHHHHHHHHHHHHHHHC.--SEEEEEEEEEES...STTT-TT-E CS
   PNP_UDP_1   3 aiivgspgevellaespleetpfgre...grgfkfvtGtlkgkpvvivstG...iGkpnaavvaeirllkef.gvkaiiriGtaGgl...npdlkvGDv 91 
                 a + + p e ++ ae  l+e+++ ++   + +  +v+G++++++vv+++     +G  +aa   + rl  +f ++k  +++G+ Gg+    +d+++GDv
  EEA19454.1  14 AWVSALPLESAAAAEM-LDEKHCDPRshgSNTDQYVFGQVGNHNVVMARLPsgqMGNNSAA-DVAGRLTTAFpSIKFALMVGIGGGVptaSADIRLGDV 110
                 5567778788888888.99999999988888899***************9899********.9999****9*889999**********9999******* PP

                 EEEEEEEESSSCCGCCTHHCC..........................TCCCCTTSSEE--HHHHHHHHH.................CHHTTT....... CS
   PNP_UDP_1  92 vipddainfdgrsplygpkee..........................gqyfpdsydapadpelrallke.................aaealg....... 140
                 v+   + ++ g  ++ + k +                          + +++  +d+pa+ +  ++l +                 +            
  EEA19454.1 111 VVGHPHSQHGGVVQYDFGKTGpngqvhrtgfinappkvllnaiaklrENHYRRLNDVPAHLSAFDRLAQfsrntagpdvlfqaaykH----Sggddces 205
                 ******99999999888777789889999******************8888888888899999999999666666666666544440....15666666 PP

                 ................TTEEEEEEEEESESS-CHHHHHHHHHHTC.-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTBETTCTCH.HCCCHHHHHHH CS
   PNP_UDP_1 141 ................ikvhrGvvatadgfyaeteaelrllrrlg.adaveMEtaavaqlArelgipfaairvvsdlaaggadaeatheeveefaqeaa 222
                                 + +h+G++a+++++  + + ++r+  +lg + + eME+a +a +      p a+ir++ d+a+           ++  ++ aa
  EEA19454.1 206 cnkemiierprreskeVIIHYGTIASGNQVMKDGVTRDRISVELGgVLCFEMEGAGLAGA-----FPSAVIRGICDYADS--------HKNKSWQPYAA 291
                 666677777788888899*********************77777769999****998865.....899999999997777........66666667777 PP

                 HHHHHHHHHHH CS
   PNP_UDP_1 223 knaaalllall 233
                  +aaa++++ll
  EEA19454.1 292 ATAAAFAKELL 302
                 77777776665 PP

>> DUF2225  Uncharacterized protein conserved in bacteria (DUF2225)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.7   0.6   0.00072      0.32      86     181 ..     767     858 ..     731     878 .. 0.67
   2 ?    6.0   0.5     0.021         9      91     160 ..     856     926 ..     849     960 .. 0.64
   3 ?    6.9   0.2     0.011       4.7      91     169 ..     982    1062 ..     967    1083 .. 0.72
   4 ?    6.2   0.0     0.017       7.3      87     151 ..    1104    1169 ..    1089    1188 .. 0.77
   5 ?    4.3   0.1     0.067        29      92     153 ..    1151    1213 ..    1142    1224 .. 0.73
   6 !   12.3   0.5   0.00024       0.1      88     192 ..    1189    1293 ..    1182    1298 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00072
     DUF2225  86 dfskertldeaiesYkLallcyelkkekks.kkAklalrlAWlyrdkedeekeklflkkAlelykeayekesfpvegideatvlYLiaeLerrlgnk 181
                   s+  +l +a + Y+ al+ ye     +  +   ++ +l+ ly d+++ +  ++ +++Ale+y++a  ++++++     +  +  +++L +  g+ 
  EEA19454.1 767 LLSDRGNLGKAEKMYQRALEGYEKAWGPDHtSTLDTVNNLGLLYADQGKLTDAEKMYQRALEGYEKAWGSNHTST-----LDTVNNLGNLYKNQGKL 858
                 455666888999999999999988877776355567778999999999999999999999999999998776632.....22233344555555555 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.021
     DUF2225  91 rtldeaiesYkLallcyelkkekks.kkAklalrlAWlyrdkedeekeklflkkAlelykeayekesfpve 160
                  +l +a + Y+ al+  e     +  +   ++ +l+ ly d+++    ++ +++Ale+y++a   +++++ 
  EEA19454.1 856 GKLADAEKMYQRALEGKEKAWGPDHtSTLDTVNNLGLLYADQGKLVDAEKMYQRALEGYEKAWGPDHTSIL 926
                 56666777777777775555544442444566678899999999999999999999999999877766443 PP

  == domain 3  score: 6.9 bits;  conditional E-value: 0.011
     DUF2225   91 rtldeaiesYkLallcyelkkekks.kkAklalrlAWlyrdkedeekeklflkkAlelykeayekesfpv.egideatvlY 169 
                   +l +a + Y+ al+  e     +  +   ++ +l+ ly ++++ +  ++ +++Ale+y++a   +++++ + ++++ +lY
  EEA19454.1  982 GKLVDAEKMYQRALEGKEKAWGPDHtSTLDTVNNLGLLYTNQGKLTDAEKMYQRALEGYEKAWGPDHTSTlDTVNNLGLLY 1062
                  5666777777777777655555444245556678999************************98766554314555555555 PP

  == domain 4  score: 6.2 bits;  conditional E-value: 0.017
     DUF2225   87 fskertldeaiesYkLallcyelkkekks.kkAklalrlAWlyrdkedeekeklflkkAlelykea 151 
                  ++++ +l++a + Y+Lal+ ye     +  +  +++ +l+ ly d+++ +  ++ +++Ale+  +a
  EEA19454.1 1104 YAGQGKLTDAEKMYQLALEGYEKALGPDHiSTLGIVNNLGNLYVDQGKLTDAEKMYQRALEGKVKA 1169
                  677888999999999999998887766664666777889999999999999999999999876555 PP

  == domain 5  score: 4.3 bits;  conditional E-value: 0.067
     DUF2225   92 tldeaiesYkLallc.yelkkekkskkAklalrlAWlyrdkedeekeklflkkAlelykeaye 153 
                  +l++a + Y+ al+   ++    +++   ++ +l+ ly d+++    ++ +++Ale+y++a  
  EEA19454.1 1151 KLTDAEKMYQRALEGkVKACGPDHTSTLDTVNNLGLLYADQGKLVDAEKMYQRALEGYEKAWG 1213
                  566666777777766333334444455566778899***********************9975 PP

  == domain 6  score: 12.3 bits;  conditional E-value: 0.00024
     DUF2225   88 skertldeaiesYkLallcyelkkekks.kkAklalrlAWlyrdkedeekeklflkkAlelykeayekesfpvegideatvlYLiaeLerrlgnkee 183 
                  +++ +l +a + Y+ al+ ye     +  +   ++ +l+ ly d+++ e  ++++++Ale+y++a+  ++   + + +++ +Y  + L    g+ ++
  EEA19454.1 1189 ADQGKLVDAEKMYQRALEGYEKAWGPDHtSTLDTVNNLGLLYADQGKLEDAEKLYQRALEGYEKALGPDNI-LSYVPALNNAYSYGMLLEDKGRLRD 1284
                  55667888999999999999988777763555677789***************************999988.7788888888888888888888888 PP

     DUF2225  184 alrwlskvi 192 
                  a+ ++ + +
  EEA19454.1 1285 AKLMYTRAL 1293
                  888877765 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.0   0.0       1.7   7.3e+02       6      22 ..     770     786 ..     767     786 .. 0.91
   2 !    8.0   0.2     0.005       2.2       1      22 [.     807     828 ..     807     828 .. 0.95
   3 ?    6.4   0.9     0.016         7       1      22 [.     849     870 ..     849     874 .. 0.95
   4 ?    4.4   0.2     0.069        30       1      22 [.     891     912 ..     891     912 .. 0.95
   5 !   10.3   0.4     0.001      0.44       1      22 [.     933     954 ..     933     958 .. 0.94
   6 ?    4.6   0.3     0.058        25       1      22 [.     975     996 ..     975    1000 .. 0.94
   7 ?    6.2   0.1     0.019       8.2       1      22 [.    1017    1038 ..    1017    1038 .. 0.95
   8 ?    2.7   0.4      0.23     1e+02       1      22 [.    1059    1080 ..    1056    1080 .. 0.77
   9 ?    1.7   0.8      0.47   2.1e+02       1      21 [.    1101    1121 ..    1098    1128 .. 0.79
  10 !   12.2   0.1   0.00025      0.11       1      22 [.    1143    1164 ..    1143    1165 .. 0.97
  11 ?    4.4   0.2     0.069        30       1      22 [.    1185    1206 ..    1185    1206 .. 0.95
  12 !   11.0   0.9   0.00058      0.25       1      22 [.    1227    1248 ..    1227    1249 .. 0.95

  Alignments for each domain:
  == domain 1  score: -0.0 bits;  conditional E-value: 1.7
      TPR_11   6 eqGkyeeAieaYkkAlk 22 
                 ++G++ +A + Y++Al+
  EEA19454.1 770 DRGNLGKAEKMYQRALE 786
                 799************97 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.005
      TPR_11   1 GdayyeqGkyeeAieaYkkAlk 22 
                 G +y +qGk+++A + Y++Al+
  EEA19454.1 807 GLLYADQGKLTDAEKMYQRALE 828
                 789*****************97 PP

  == domain 3  score: 6.4 bits;  conditional E-value: 0.016
      TPR_11   1 GdayyeqGkyeeAieaYkkAlk 22 
                 G++y  qGk+ +A + Y++Al+
  EEA19454.1 849 GNLYKNQGKLADAEKMYQRALE 870
                 9*******************97 PP

  == domain 4  score: 4.4 bits;  conditional E-value: 0.069
      TPR_11   1 GdayyeqGkyeeAieaYkkAlk 22 
                 G +y +qGk+ +A + Y++Al+
  EEA19454.1 891 GLLYADQGKLVDAEKMYQRALE 912
                 789*****************97 PP

  == domain 5  score: 10.3 bits;  conditional E-value: 0.001
      TPR_11   1 GdayyeqGkyeeAieaYkkAlk 22 
                 G +y +qGk+e+A + Y++Al+
  EEA19454.1 933 GLLYADQGKLEDAEKMYQRALE 954
                 789*****************97 PP

  == domain 6  score: 4.6 bits;  conditional E-value: 0.058
      TPR_11   1 GdayyeqGkyeeAieaYkkAlk 22 
                 G +y +qGk+ +A + Y++Al+
  EEA19454.1 975 GLLYADQGKLVDAEKMYQRALE 996
                 789*****************97 PP

  == domain 7  score: 6.2 bits;  conditional E-value: 0.019
      TPR_11    1 GdayyeqGkyeeAieaYkkAlk 22  
                  G +y+ qGk+++A + Y++Al+
  EEA19454.1 1017 GLLYTNQGKLTDAEKMYQRALE 1038
                  789*****************97 PP

  == domain 8  score: 2.7 bits;  conditional E-value: 0.23
      TPR_11    1 GdayyeqGkyeeAieaYkkAlk 22  
                  G +y  qGk+ +A + Y++Al+
  EEA19454.1 1059 GLLYANQGKLVDAEKMYQQALE 1080
                  6678888888888888888875 PP

  == domain 9  score: 1.7 bits;  conditional E-value: 0.47
      TPR_11    1 GdayyeqGkyeeAieaYkkAl 21  
                  G++y  qGk+++A + Y+ Al
  EEA19454.1 1101 GNLYAGQGKLTDAEKMYQLAL 1121
                  788888888888877777776 PP

  == domain 10  score: 12.2 bits;  conditional E-value: 0.00025
      TPR_11    1 GdayyeqGkyeeAieaYkkAlk 22  
                  G++y++qGk+++A + Y++Al+
  EEA19454.1 1143 GNLYVDQGKLTDAEKMYQRALE 1164
                  9*******************97 PP

  == domain 11  score: 4.4 bits;  conditional E-value: 0.069
      TPR_11    1 GdayyeqGkyeeAieaYkkAlk 22  
                  G +y +qGk+ +A + Y++Al+
  EEA19454.1 1185 GLLYADQGKLVDAEKMYQRALE 1206
                  789*****************97 PP

  == domain 12  score: 11.0 bits;  conditional E-value: 0.00058
      TPR_11    1 GdayyeqGkyeeAieaYkkAlk 22  
                  G +y +qGk+e+A + Y++Al+
  EEA19454.1 1227 GLLYADQGKLEDAEKLYQRALE 1248
                  789*****************97 PP

>> RPN7  26S proteasome subunit RPN7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.1         2   8.8e+02      12      64 ..     735     786 ..     729     791 .. 0.82
   2 ?    4.3   0.1     0.069        30      32      64 ..     796     828 ..     779     836 .. 0.82
   3 ?    3.6   0.0      0.11        48      33      64 ..     839     870 ..     831     875 .. 0.90
   4 ?    1.9   0.0      0.36   1.6e+02      33      64 ..     881     912 ..     870     914 .. 0.89
   5 ?    6.4   0.1     0.015       6.4      32      64 ..     922     954 ..     905     960 .. 0.82
   6 ?    0.6   0.0       0.9   3.9e+02      38      64 ..     970     996 ..     964    1007 .. 0.89
   7 ?    3.2   0.0      0.14        63      33      64 ..    1007    1038 ..     993    1048 .. 0.88
   8 ?    1.3   0.0      0.56   2.4e+02      34      64 ..    1050    1080 ..    1047    1085 .. 0.87
   9 ?    0.4   0.0       1.1   4.7e+02      34      64 ..    1092    1122 ..    1088    1133 .. 0.86
  10 ?    4.8   0.1     0.047        21      34      65 ..    1134    1165 ..    1108    1170 .. 0.78
  11 ?    1.9   0.0      0.36   1.6e+02      34      64 ..    1176    1206 ..    1173    1216 .. 0.89
  12 ?    4.9   0.0     0.042        18      34      64 ..    1218    1248 ..    1212    1260 .. 0.89

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 2
                 HHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHCT-HHHHHHHHHTCCC CS
        RPN7  12 nekeleeLdaelkdakenlgkeeirrakldlaehYlkigdleeAlkaysrire 64 
                 +e+ +e++++   d   +++ ee+  a +  +    + g+l +A k+y+r++e
  EEA19454.1 735 AESCIERMERATAD-TMTEVNEEVSYALHMMGILLSDRGNLGKAEKMYQRALE 786
                 55667777777777.67889999999999999999999**********99876 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.069
                 HHHHHHHHHHHHHHHHHCT-HHHHHHHHHTCCC CS
        RPN7  32 keeirrakldlaehYlkigdleeAlkaysrire 64 
                  +++ ++ ++l+  Y++ g+l+ A k+y+r++e
  EEA19454.1 796 HTSTLDTVNNLGLLYADQGKLTDAEKMYQRALE 828
                 567888999*********************987 PP

  == domain 3  score: 3.6 bits;  conditional E-value: 0.11
                 HHHHHHHHHHHHHHHHCT-HHHHHHHHHTCCC CS
        RPN7  33 eeirrakldlaehYlkigdleeAlkaysrire 64 
                 +++ ++ ++l++ Y + g+l+ A k+y+r++e
  EEA19454.1 839 TSTLDTVNNLGNLYKNQGKLADAEKMYQRALE 870
                 67788899*********************987 PP

  == domain 4  score: 1.9 bits;  conditional E-value: 0.36
                 HHHHHHHHHHHHHHHHCT-HHHHHHHHHTCCC CS
        RPN7  33 eeirrakldlaehYlkigdleeAlkaysrire 64 
                 +++ ++ ++l+  Y++ g+l  A k+y+r++e
  EEA19454.1 881 TSTLDTVNNLGLLYADQGKLVDAEKMYQRALE 912
                 577788999********************986 PP

  == domain 5  score: 6.4 bits;  conditional E-value: 0.015
                 HHHHHHHHHHHHHHHHHCT-HHHHHHHHHTCCC CS
        RPN7  32 keeirrakldlaehYlkigdleeAlkaysrire 64 
                  ++i ++ ++l+  Y++ g+le A k+y+r++e
  EEA19454.1 922 HTSILNTVNNLGLLYADQGKLEDAEKMYQRALE 954
                 57899999**********************987 PP

  == domain 6  score: 0.6 bits;  conditional E-value: 0.9
                 HHHHHHHHHHHCT-HHHHHHHHHTCCC CS
        RPN7  38 akldlaehYlkigdleeAlkaysrire 64 
                 + ++l+  Y++ g+l  A k+y+r++e
  EEA19454.1 970 TVNNLGLLYADQGKLVDAEKMYQRALE 996
                 5678999*****************986 PP

  == domain 7  score: 3.2 bits;  conditional E-value: 0.14
                  HHHHHHHHHHHHHHHHCT-HHHHHHHHHTCCC CS
        RPN7   33 eeirrakldlaehYlkigdleeAlkaysrire 64  
                  +++ ++ ++l+  Y++ g+l+ A k+y+r++e
  EEA19454.1 1007 TSTLDTVNNLGLLYTNQGKLTDAEKMYQRALE 1038
                  677888999********************986 PP

  == domain 8  score: 1.3 bits;  conditional E-value: 0.56
                  HHHHHHHHHHHHHHHCT-HHHHHHHHHTCCC CS
        RPN7   34 eirrakldlaehYlkigdleeAlkaysrire 64  
                  ++ ++ ++l+  Y++ g+l  A k+y++++e
  EEA19454.1 1050 STLDTVNNLGLLYANQGKLVDAEKMYQQALE 1080
                  67778899********************987 PP

  == domain 9  score: 0.4 bits;  conditional E-value: 1.1
                  HHHHHHHHHHHHHHHCT-HHHHHHHHHTCCC CS
        RPN7   34 eirrakldlaehYlkigdleeAlkaysrire 64  
                  ++ ++ ++l++ Y+  g+l+ A k+y+ ++e
  EEA19454.1 1092 STLDTVNNLGNLYAGQGKLTDAEKMYQLALE 1122
                  67788899******************97655 PP

  == domain 10  score: 4.8 bits;  conditional E-value: 0.047
                  HHHHHHHHHHHHHHHCT-HHHHHHHHHTCCCC CS
        RPN7   34 eirrakldlaehYlkigdleeAlkaysrirey 65  
                  ++    ++l++ Y++ g+l+ A k+y+r++e 
  EEA19454.1 1134 STLGIVNNLGNLYVDQGKLTDAEKMYQRALEG 1165
                  44556789********************9885 PP

  == domain 11  score: 1.9 bits;  conditional E-value: 0.36
                  HHHHHHHHHHHHHHHCT-HHHHHHHHHTCCC CS
        RPN7   34 eirrakldlaehYlkigdleeAlkaysrire 64  
                  ++ ++ ++l+  Y++ g+l  A k+y+r++e
  EEA19454.1 1176 STLDTVNNLGLLYADQGKLVDAEKMYQRALE 1206
                  67778899********************986 PP

  == domain 12  score: 4.9 bits;  conditional E-value: 0.042
                  HHHHHHHHHHHHHHHCT-HHHHHHHHHTCCC CS
        RPN7   34 eirrakldlaehYlkigdleeAlkaysrire 64  
                  ++ ++ ++l+  Y++ g+le A k+y+r++e
  EEA19454.1 1218 STLDTVNNLGLLYADQGKLEDAEKLYQRALE 1248
                  67788899********************986 PP

>> PPR  PPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.0       6.7   2.9e+03      12      25 ..     770     783 ..     767     786 .. 0.82
   2 ?    1.4   0.0       1.1   4.7e+02       8      25 ..     808     825 ..     801     828 .. 0.81
   3 ?    2.5   0.0      0.48   2.1e+02       2      25 ..     844     867 ..     843     871 .. 0.89
   4 ?    1.4   0.0       1.1   4.9e+02       8      25 ..     892     909 ..     885     912 .. 0.81
   5 ?    4.3   0.0      0.13        57       9      25 ..     935     951 ..     928     955 .. 0.83
   6 ?    1.4   0.0       1.1   4.6e+02       8      25 ..     976     993 ..     969     997 .. 0.81
   7 ?    1.1   0.0       1.3   5.7e+02       9      25 ..    1019    1035 ..    1011    1038 .. 0.81
   8 ?    2.4   0.0      0.52   2.3e+02       8      25 ..    1060    1077 ..    1053    1082 .. 0.81
   9 ?    2.7   0.0      0.42   1.8e+02       2      24 ..    1096    1118 ..    1095    1122 .. 0.90
  10 ?    3.2   0.0      0.29   1.3e+02       4      25 ..    1140    1161 ..    1138    1167 .. 0.86
  11 ?    1.4   0.0       1.1   4.9e+02       8      25 ..    1186    1203 ..    1179    1206 .. 0.81
  12 ?    5.0   0.0     0.079        34       8      25 ..    1228    1245 ..    1221    1248 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 6.7
         PPR  12 knGkleeAlelfke 25 
                   G+l +A++++++
  EEA19454.1 770 DRGNLGKAEKMYQR 783
                 5799*******987 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 1.1
         PPR   8 sgycknGkleeAlelfke 25 
                   y+  Gkl +A++++++
  EEA19454.1 808 LLYADQGKLTDAEKMYQR 825
                 57999**********987 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.48
         PPR   2 tynslIsgycknGkleeAlelfke 25 
                 t n l + y   Gkl +A++++++
  EEA19454.1 844 TVNNLGNLYKNQGKLADAEKMYQR 867
                 77999999**************87 PP

  == domain 4  score: 1.4 bits;  conditional E-value: 1.1
         PPR   8 sgycknGkleeAlelfke 25 
                   y+  Gkl +A++++++
  EEA19454.1 892 LLYADQGKLVDAEKMYQR 909
                 57999**********987 PP

  == domain 5  score: 4.3 bits;  conditional E-value: 0.13
         PPR   9 gycknGkleeAlelfke 25 
                  y+  Gkle+A++++++
  EEA19454.1 935 LYADQGKLEDAEKMYQR 951
                 6999***********87 PP

  == domain 6  score: 1.4 bits;  conditional E-value: 1.1
         PPR   8 sgycknGkleeAlelfke 25 
                   y+  Gkl +A++++++
  EEA19454.1 976 LLYADQGKLVDAEKMYQR 993
                 57999**********987 PP

  == domain 7  score: 1.1 bits;  conditional E-value: 1.3
         PPR    9 gycknGkleeAlelfke 25  
                   y   Gkl +A++++++
  EEA19454.1 1019 LYTNQGKLTDAEKMYQR 1035
                  6999**********987 PP

  == domain 8  score: 2.4 bits;  conditional E-value: 0.52
         PPR    8 sgycknGkleeAlelfke 25  
                    y+  Gkl +A++++++
  EEA19454.1 1060 LLYANQGKLVDAEKMYQQ 1077
                  579************986 PP

  == domain 9  score: 2.7 bits;  conditional E-value: 0.42
         PPR    2 tynslIsgycknGkleeAlelfk 24  
                  t n l + y+  Gkl +A+++++
  EEA19454.1 1096 TVNNLGNLYAGQGKLTDAEKMYQ 1118
                  7799999**************97 PP

  == domain 10  score: 3.2 bits;  conditional E-value: 0.29
         PPR    4 nslIsgycknGkleeAlelfke 25  
                  n l + y+  Gkl +A++++++
  EEA19454.1 1140 NNLGNLYVDQGKLTDAEKMYQR 1161
                  777899**************97 PP

  == domain 11  score: 1.4 bits;  conditional E-value: 1.1
         PPR    8 sgycknGkleeAlelfke 25  
                    y+  Gkl +A++++++
  EEA19454.1 1186 LLYADQGKLVDAEKMYQR 1203
                  57999**********987 PP

  == domain 12  score: 5.0 bits;  conditional E-value: 0.079
         PPR    8 sgycknGkleeAlelfke 25  
                    y+  Gkle+A++l+++
  EEA19454.1 1228 LLYADQGKLEDAEKLYQR 1245
                  57999***********87 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.4   0.0   1.2e-10   5.1e-08      14     230 ..     360     579 ..     345     603 .. 0.72

  Alignments for each domain:
  == domain 1  score: 32.4 bits;  conditional E-value: 1.2e-10
                 CTTTSCSEEEEEEESTTSSHHHHHHHHCCSHCCCCCCBTEEEEEEEESXXHHHHHHHXXHHHHHCCCTTSSSS-STTS......HHHHHHHHC...... CS
      NB-ARC  14 ekdelqslvvalvGmgGvGKttlakqilnksdevegrFdsvawvvvsktdkseeiletilkeLslseddleekeeves......lkrklvrlL...... 100
                 ++++  + vv l+G gG+GKt la++  +k    +  F sv w+  s +d+ ++ + +   ++ +   ++ e + ++s      lk  +  ++      
  EEA19454.1 360 QSEDYRQQVVVLHGLGGIGKTQLAAEFARK---HQAAFTSVFWLDGSSEDSLKQSIADYSGRIPE--GQIPETSRKYSssangdLKAVINDFMewlskt 453
                 46777779*********************9...6789*******888877766655555555522..23333333333445677555555554222322 PP

                 CCTTEEEEEEEE....-SHHH..H.....HHHHCHTTSEEEEEESBCCCCCCS-S-EEEEEESS--HHHHHHHHHHCCTS-GGCHH..CHHHHHHHHHH CS
      NB-ARC 101 ltkrfllvlDDV....weeed..wdkigvvlparenrlrvllTTRdeevanavsatsekievelLekdeawellenkvfekkleekesleevakeivek 193
                 ++k  l+++D V     +e+d    +++  +p +     +l+TTR  ++  ++    e++++e     +a  ++ +  ++  + ++       +e+ + 
  EEA19454.1 454 ENKHWLIIFDNVdrdyQQENDinAYSVSNYIP-EVDHGLILITTRLANL--QHL--GETLQLETVDMSQAQAIFRKWYNQDFDPND------SNELLRL 541
                 3569******9954423344444225666778.5566679*******99..333..479***************999888777766......6899999 PP

                 CTT-HHHHHHHHHHHC-T.CSCCHHHHHHHHHHCTGCC CS
      NB-ARC 194 ckGlPlalkvlggllstk.ktveewkkvleklesklle 230
                   GlPlal+  ++ +s     ++ + +++++  + l+e
  EEA19454.1 542 LDGLPLALAQAAAYMSETgASFSTYTRLYKERWKDLME 579
                 9**************98888888888888765555555 PP

>> TPR_21  Tetratricopeptide repeat-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   7.0     0.012       5.3      22     178 ..     711     874 ..     708     889 .. 0.69
   2 ?    3.8   0.1     0.091        40     154     178 ..     892     916 ..     886     932 .. 0.86
   3 ?    6.3   0.2     0.016         7     154     178 ..     934     958 ..     927     975 .. 0.85
   4 ?    4.1   0.2     0.074        32     155     178 ..     977    1000 ..     973    1015 .. 0.87
   5 ?    5.7   0.1     0.025        11     153     178 ..    1017    1042 ..    1011    1056 .. 0.88
   6 ?    4.2   0.1     0.071        31     153     176 ..    1059    1082 ..    1053    1099 .. 0.88
   7 ?    5.4   0.2      0.03        13     153     178 ..    1101    1126 ..    1095    1133 .. 0.90
   8 !    8.2   0.1    0.0043       1.9     153     176 ..    1143    1166 ..    1138    1182 .. 0.90
   9 ?    3.5   0.2      0.12        50     155     178 ..    1187    1210 ..    1182    1221 .. 0.88
  10 ?    5.1   0.2     0.038        17     154     178 ..    1228    1252 ..    1222    1262 .. 0.86

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.012
      TPR_21  22 laGwqgwqdyqeeqaeeAsalYqqlqeaveakdaakakeaaeeladeyggtaYa..alaaLllAkaav..eagdlaaAkaqLewvlekakdeelkalar 116
                 ++G+ +  ++ +e  ++  +l+ + ++  e+ ++a     a+++ + +++ +Ya   ++ Ll+ + +   +++ +++A + +e++    +  +l+++ +
  EEA19454.1 711 VIGYAVPDKHATEYHQKQRQLFAHAESCIERMERA----TADTMTEVNEEVSYAlhMMGILLSDRGNLgkAEKMYQRALEGYEKAWGPDHTSTLDTVNN 805
                 66666667777777777777777776655555555....344444555555555314555555444441155667888888888888888888999998 PP

      TPR_21 117 lRLa.....rvllaekkydeAlktLeakkeeafaalvaelr..GDilvaqgkldeAraaYqaAlaalee 178
                 l L      ++  aek y++Al+  e++  ++ ++  + +   G+++ +qgkl++A + Yq+Al+ +e+
  EEA19454.1 806 LGLLyadqgKLTDAEKMYQRALEGYEKAWGSNHTSTLDTVNnlGNLYKNQGKLADAEKMYQRALEGKEK 874
                 8884223335667778888888888888888888877766455*********************98876 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.091
      TPR_21 154 DilvaqgkldeAraaYqaAlaalee 178
                  +++ qgkl +A + Yq+Al+  e+
  EEA19454.1 892 LLYADQGKLVDAEKMYQRALEGYEK 916
                 5799****************98766 PP

  == domain 3  score: 6.3 bits;  conditional E-value: 0.016
      TPR_21 154 DilvaqgkldeAraaYqaAlaalee 178
                  +++ qgkl++A + Yq+Al+ +e+
  EEA19454.1 934 LLYADQGKLEDAEKMYQRALEGKET 958
                 5899****************98776 PP

  == domain 4  score: 4.1 bits;  conditional E-value: 0.074
      TPR_21  155 ilvaqgkldeAraaYqaAlaalee 178 
                  +++ qgkl +A + Yq+Al+ +e+
  EEA19454.1  977 LYADQGKLVDAEKMYQRALEGKEK 1000
                  7999***************98876 PP

  == domain 5  score: 5.7 bits;  conditional E-value: 0.025
      TPR_21  153 GDilvaqgkldeAraaYqaAlaalee 178 
                  G ++++qgkl++A + Yq+Al+  e+
  EEA19454.1 1017 GLLYTNQGKLTDAEKMYQRALEGYEK 1042
                  55899****************98765 PP

  == domain 6  score: 4.2 bits;  conditional E-value: 0.071
      TPR_21  153 GDilvaqgkldeAraaYqaAlaal 176 
                  G ++++qgkl +A + Yq+Al+ +
  EEA19454.1 1059 GLLYANQGKLVDAEKMYQQALEGK 1082
                  55899***************9875 PP

  == domain 7  score: 5.4 bits;  conditional E-value: 0.03
      TPR_21  153 GDilvaqgkldeAraaYqaAlaalee 178 
                  G++++ qgkl++A + Yq Al+  e+
  EEA19454.1 1101 GNLYAGQGKLTDAEKMYQLALEGYEK 1126
                  99*******************97665 PP

  == domain 8  score: 8.2 bits;  conditional E-value: 0.0043
      TPR_21  153 GDilvaqgkldeAraaYqaAlaal 176 
                  G+++v qgkl++A + Yq+Al+ +
  EEA19454.1 1143 GNLYVDQGKLTDAEKMYQRALEGK 1166
                  99*******************875 PP

  == domain 9  score: 3.5 bits;  conditional E-value: 0.12
      TPR_21  155 ilvaqgkldeAraaYqaAlaalee 178 
                  +++ qgkl +A + Yq+Al+  e+
  EEA19454.1 1187 LYADQGKLVDAEKMYQRALEGYEK 1210
                  7999***************98765 PP

  == domain 10  score: 5.1 bits;  conditional E-value: 0.038
      TPR_21  154 DilvaqgkldeAraaYqaAlaalee 178 
                   +++ qgkl++A + Yq+Al+  e+
  EEA19454.1 1228 LLYADQGKLEDAEKLYQRALEGYEK 1252
                  5899****************98766 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       7.1   3.1e+03      54      88 ..     274     308 ..     262     321 .. 0.64
   2 !   24.6   0.0   6.2e-08   2.7e-05       2     146 ..     339     467 ..     338     479 .. 0.67

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 7.1
      AAA_16  54 iflrgkcdqlesaipysa.laqalareellrqllde 88 
                 i+ +++ ++++s  py+a  a a+a+ ellr + +e
  EEA19454.1 274 ICDYADSHKNKSWQPYAAaTAAAFAK-ELLRVVPAE 308
                 33333344445559998867777755.888877766 PP

  == domain 2  score: 24.6 bits;  conditional E-value: 6.2e-08
      AAA_16   2 lvGReeeleqLlsalervrsgrp.....elvllsGesGvGKsslvrellralekd..ggiflrgkcdqlesaipysalaqalareellrqlldeaesae 93 
                 +  R ee+++L+++l + r+ ++     ++v+l+G  G+GK+ l+ e++r  +++   +++l g  +++                 l + ++d +    
  EEA19454.1 339 FADRPEEMRRLEQVLLPHRQVQSedyrqQVVVLHGLGGIGKTQLAAEFARKHQAAftSVFWLDGSSEDS-----------------LKQSIADYSGRIP 420
                 5668899999999999777777777899*********************96666632233355555555.................3333333322222 PP

      AAA_16  94 leawrekleealaavpelagaeasrllellkrllallsrderp.lvlvlDdlqw 146
                  ++ +e+ +       + ++++  +l ++++++++ ls++e + +++++D++++
  EEA19454.1 421 EGQIPETSR-------KYSSSANGDLKAVINDFMEWLSKTENKhWLIIFDNVDR 467
                 222222222.......22333447899999999977777777669999999996 PP

>> Ribosomal_S7  Ribosomal protein S7p/S5e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.51   2.2e+02      14      60 ..     794     840 ..     780     872 .. 0.64
   2 ?    1.0   0.0      0.66   2.9e+02      11      48 ..     875     912 ..     837     955 .. 0.58
   3 ?    2.3   0.0      0.27   1.2e+02       9      53 ..     999    1043 ..     990    1088 .. 0.73
   4 ?   -0.4   0.0       1.8   7.8e+02      15      55 ..    1089    1129 ..    1076    1137 .. 0.79
   5 ?    4.1   0.0     0.077        34      11      48 ..    1127    1164 ..    1120    1206 .. 0.89
   6 ?    1.9   0.0      0.35   1.5e+02      13      69 ..    1213    1269 ..    1166    1272 .. 0.77

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.51
                   --SSTTSBHHHHHHHHHSBTTBHHHHHHHHHHHHHHHHHHHSS-HHH CS
  Ribosomal_S7  14 pdpkynselveklinklmkdGkkslAekivygaldiieektkkdple 60 
                   pd +   ++v+ l      +Gk + Aek+ ++al+  e+  +++  +
    EEA19454.1 794 PDHTSTLDTVNNLGLLYADQGKLTDAEKMYQRALEGYEKAWGSNHTS 840
                   55555666666666666678888888888888888777764443333 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.66
                   -----SSTTSBHHHHHHHHHSBTTBHHHHHHHHHHHHH CS
  Ribosomal_S7  11 evlpdpkynselveklinklmkdGkkslAekivygald 48 
                      pd +   ++v+ l      +Gk   Aek+ ++al+
    EEA19454.1 875 AWGPDHTSTLDTVNNLGLLYADQGKLVDAEKMYQRALE 912
                   33334444444444444444444555555555555554 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.27
                    T------SSTTSBHHHHHHHHHSBTTBHHHHHHHHHHHHHHHHHH CS
  Ribosomal_S7    9 krevlpdpkynselveklinklmkdGkkslAekivygaldiieek 53  
                    ++   pd +   ++v+ l    +++Gk + Aek+ ++al+  e+ 
    EEA19454.1  999 EKAWGPDHTSTLDTVNNLGLLYTNQGKLTDAEKMYQRALEGYEKA 1043
                    4566788888888888888889999************99988876 PP

  == domain 4  score: -0.4 bits;  conditional E-value: 1.8
                    -SSTTSBHHHHHHHHHSBTTBHHHHHHHHHHHHHHHHHHHS CS
  Ribosomal_S7   15 dpkynselveklinklmkdGkkslAekivygaldiieektk 55  
                    + +   ++v+ l n    +Gk + Aek+ + al+  e+  +
    EEA19454.1 1089 NHTSTLDTVNNLGNLYAGQGKLTDAEKMYQLALEGYEKALG 1129
                    555666788999999999**************998777655 PP

  == domain 5  score: 4.1 bits;  conditional E-value: 0.077
                    -----SSTTSBHHHHHHHHHSBTTBHHHHHHHHHHHHH CS
  Ribosomal_S7   11 evlpdpkynselveklinklmkdGkkslAekivygald 48  
                     + pd +    +v+ l n  + +Gk + Aek+ ++al+
    EEA19454.1 1127 ALGPDHISTLGIVNNLGNLYVDQGKLTDAEKMYQRALE 1164
                    67799999999*************************98 PP

  == domain 6  score: 1.9 bits;  conditional E-value: 0.35
                    ---SSTTSBHHHHHHHHHSBTTBHHHHHHHHHHHHHHHHHHHSS-HHHHHHHHHHHC CS
  Ribosomal_S7   13 lpdpkynselveklinklmkdGkkslAekivygaldiieektkkdplevleeAlenv 69  
                     pd +   ++v+ l      +Gk + Aek+ ++al+  e+  + d +  ++ Al+n+
    EEA19454.1 1213 GPDHTSTLDTVNNLGLLYADQGKLEDAEKLYQRALEGYEKALGPDNILSYVPALNNA 1269
                    466666666666666666778999999999999998888887778777777777775 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0     4e-06    0.0018       1     128 [.     339     466 ..     339     485 .. 0.74
   2 ?   -1.4   0.0       4.1   1.8e+03     192     232 ..     513     551 ..     497     552 .. 0.72

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 4e-06
    ATPase_2   1 FfdRekelkeleeil........erepneiyfiYGpegsGKtaLlkeiienledkdkyviyyialreesiskldefieeeeekkklekalgiavpkael 91 
                 F+dR +e+++le++l        e  +++++++ G  g+GKt+L  e++ +++   +  ++  + ++e++ k +      ++ +  e ++ ++ +k   
  EEA19454.1 339 FADRPEEMRRLEQVLlphrqvqsEDYRQQVVVLHGLGGIGKTQLAAEFARKHQA-AFTSVFWLDGSSEDSLKQSIA---DYSGRIPEGQIPETSRKY-- 431
                 899999999999987555544334557899*******************99966.666777766666555554444...355554555554444444.. PP

    ATPase_2  92 eeilkeksklvfkaielllekikkkgkk.iiiiiDelq 128
                    +++ + ++++ i++++e ++k+  k   ii+D + 
  EEA19454.1 432 ---SSSANGDLKAVINDFMEWLSKTENKhWLIIFDNVD 466
                 ...44677899***********99998889999**986 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 4.1
    ATPase_2 192 ldketalnflkegfkeleel..skedfeeiyryvGGkPkalve 232
                 +d  +a  +++    + +++    +d +e+ r+++G P al++
  EEA19454.1 513 VDMSQAQAIFR----KWYNQdfDPNDSNELLRLLDGLPLALAQ 551
                 44455555544....456666688999***********99976 PP

>> KIF1B  Kinesin protein 1B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0       1.8   7.9e+02       4      27 ..     815     839 ..     813     847 .. 0.80
   2 ?   -1.0   0.0       5.6   2.5e+03       4      26 ..     857     879 ..     855     886 .. 0.76
   3 ?    1.0   0.0       1.3   5.8e+02       4      25 ..     899     920 ..     897     930 .. 0.82
   4 ?    0.0   0.0       2.7   1.2e+03       4      25 ..     941     962 ..     939     971 .. 0.82
   5 ?    1.1   0.0       1.2   5.4e+02       4      26 ..     983    1005 ..     981    1013 .. 0.82
   6 ?   -1.0   0.0       5.7   2.5e+03       4      26 ..    1025    1047 ..    1024    1054 .. 0.76
   7 ?    0.8   0.0       1.6   6.9e+02       4      23 ..    1067    1086 ..    1065    1096 .. 0.81
   8 ?    1.3   0.0       1.1   4.9e+02       4      26 ..    1193    1215 ..    1191    1225 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 1.8
       KIF1B   4 RlvdMRemYeeskegesrsh.svdt 27 
                 +l d   mY++  eg+++ + s++t
  EEA19454.1 815 KLTDAEKMYQRALEGYEKAWgSNHT 839
                 6667778*********999988775 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 5.6
       KIF1B   4 RlvdMRemYeeskegesrshsvd 26 
                 +l d   mY++  eg+++ + +d
  EEA19454.1 857 KLADAEKMYQRALEGKEKAWGPD 879
                 5666678*******998877544 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 1.3
       KIF1B   4 RlvdMRemYeeskegesrshsv 25 
                 +lvd   mY++  eg+++ + +
  EEA19454.1 899 KLVDAEKMYQRALEGYEKAWGP 920
                 899999*********9877744 PP

  == domain 4  score: 0.0 bits;  conditional E-value: 2.7
       KIF1B   4 RlvdMRemYeeskegesrshsv 25 
                 +l+d   mY++  eg+++ + +
  EEA19454.1 941 KLEDAEKMYQRALEGKETAWGP 962
                 7888899*******99877744 PP

  == domain 5  score: 1.1 bits;  conditional E-value: 1.2
       KIF1B    4 RlvdMRemYeeskegesrshsvd 26  
                  +lvd   mY++  eg+++ + +d
  EEA19454.1  983 KLVDAEKMYQRALEGKEKAWGPD 1005
                  899999*********99877544 PP

  == domain 6  score: -1.0 bits;  conditional E-value: 5.7
       KIF1B    4 RlvdMRemYeeskegesrshsvd 26  
                  +l d   mY++  eg+++ + +d
  EEA19454.1 1025 KLTDAEKMYQRALEGYEKAWGPD 1047
                  5666678********98877544 PP

  == domain 7  score: 0.8 bits;  conditional E-value: 1.6
       KIF1B    4 RlvdMRemYeeskegesrsh 23  
                  +lvd   mY++  eg+ + +
  EEA19454.1 1067 KLVDAEKMYQQALEGKVKAW 1086
                  899999*******9986555 PP

  == domain 8  score: 1.3 bits;  conditional E-value: 1.1
       KIF1B    4 RlvdMRemYeeskegesrshsvd 26  
                  +lvd   mY++  eg+++ + +d
  EEA19454.1 1193 KLVDAEKMYQRALEGYEKAWGPD 1215
                  899999*********99877554 PP

>> Strumpellin  Hereditary spastic paraplegia protein strumpellin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0      0.36   1.6e+02     367     447 ..     742     821 ..     728     829 .. 0.74
   2 ?    1.1   0.1      0.13        59     404     447 ..     820     863 ..     815     876 .. 0.92
   3 ?    0.5   0.0       0.2        89     404     447 ..     862     905 ..     857     914 .. 0.91
   4 ?   -0.9   0.0      0.58   2.5e+02     403     447 ..     945     989 ..     927     992 .. 0.88
   5 ?    1.9   0.0      0.08        35     404     447 ..     988    1031 ..     985    1038 .. 0.92
   6 !    5.8   0.0    0.0052       2.3     403     451 ..    1071    1119 ..    1057    1124 .. 0.92

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.36
  Strumpellin 367 kskkakqlrdlvlaelklskeellelLLetsqlElklkeifkelleekeerwekskkeavermkeLsevFsgekpLsrvek 447
                  +++++      v++e++  + +++ +LL+      k  +++++ le  e+ w    +++ + +++L  +++++ +L++ ek
   EEA19454.1 742 MERATADTMTEVNEEVS-YALHMMGILLSDRGNLGKAEKMYQRALEGYEKAWGPDHTSTLDTVNNLGLLYADQGKLTDAEK 821
                  44455555566666663.444555555544444457899*************************************99876 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.13
  Strumpellin 404 keifkelleekeerwekskkeavermkeLsevFsgekpLsrvek 447
                   +++++ le  e+ w ++ +++ + +++L ++++++ +L++ ek
   EEA19454.1 820 EKMYQRALEGYEKAWGSNHTSTLDTVNNLGNLYKNQGKLADAEK 863
                  689************************************99876 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.2
  Strumpellin 404 keifkelleekeerwekskkeavermkeLsevFsgekpLsrvek 447
                   +++++ le ke+ w    +++ + +++L  +++++ +L + ek
   EEA19454.1 862 EKMYQRALEGKEKAWGPDHTSTLDTVNNLGLLYADQGKLVDAEK 905
                  689*********************************99988765 PP

  == domain 4  score: -0.9 bits;  conditional E-value: 0.58
  Strumpellin 403 lkeifkelleekeerwekskkeavermkeLsevFsgekpLsrvek 447
                    +++++ le ke+ w    + + + +++L  +++++ +L + ek
   EEA19454.1 945 AEKMYQRALEGKETAWGPDHTLTLDTVNNLGLLYADQGKLVDAEK 989
                  578**********************************99988765 PP

  == domain 5  score: 1.9 bits;  conditional E-value: 0.08
  Strumpellin  404 keifkelleekeerwekskkeavermkeLsevFsgekpLsrvek 447 
                    +++++ le ke+ w    +++ + +++L  +++++ +L++ ek
   EEA19454.1  988 EKMYQRALEGKEKAWGPDHTSTLDTVNNLGLLYTNQGKLTDAEK 1031
                   68*************************************99876 PP

  == domain 6  score: 5.8 bits;  conditional E-value: 0.0052
  Strumpellin  403 lkeifkelleekeerwekskkeavermkeLsevFsgekpLsrveknesL 451 
                     +++++ le k + w  + +++ + +++L ++++g+ +L++ ek  +L
   EEA19454.1 1071 AEKMYQQALEGKVKAWGPNHTSTLDTVNNLGNLYAGQGKLTDAEKMYQL 1119
                   579***************************************9987666 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   2.2e-05    0.0096       4     128 ..     365     494 ..     361     503 .. 0.69

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 2.2e-05
      AAA_22   4 tagilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelka.........erlsseellealeqalrarav.i 92 
                 +++++v++G  G+GKT l+++++++++++        +v+  + +s+ s+k+   +    + +++           ++++++++++ + + l+++   +
  EEA19454.1 365 RQQVVVLHGLGGIGKTQLAAEFARKHQAA------FTSVFWLDGSSEDSLKQSIADYSGRIPEGQIPetsrkysssANGDLKAVINDFMEWLSKTENkH 457
                 7899*********************9643......3344445555555555555555555554444488899999999999999966666666666669 PP

      AAA_22  93 elliiDEaqh.lrseealeeLrsllnl.srkgvqliLv 128
                  l+i D++++   ++e+  +  s +n   + +  liL+
  EEA19454.1 458 WLIIFDNVDRdY-QQENDINAYSVSNYiPEVDHGLILI 494
                 99*******944.4444333356666565555555555 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   2.5e-05     0.011       2     163 ..     368     526 ..     367     529 .. 0.65

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 2.5e-05
                 CEEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-.........-HCHHHCCCCTS--SSS-C.................CHHHHC CS
       NACHT   2 lvilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgna......rsladllfsqlpepaapvse.................vwavll 77 
                 +v+l+G  G+GKT L++++a+    +++ +  f  vF+l  ++    +++      r +      q pe                        +++ l 
  EEA19454.1 368 VVVLHGLGGIGKTQLAAEFAR----KHQAA--FTSVFWLDGSSEDSLKQSiadysgRIP----EGQIPET-----SrkysssangdlkavindFMEWLS 451
                 89***********99998875....45455..8999**986655554433233333111....1222222.....123445777788888888999999 PP

                 CSCCCEEEEE.E-STT-SS-TCH.........HHHHHCTTTTT--EEEEEEECCCHHHHCTTSSCE..EEEE--TCCHHHHHHHHCT CS
       NACHT  78 elperlLlil.DglDelvtdlgqkekqpvrtlLselirkkllpeasllltvrpralrdleeqleeaivlevegfsesrrkqlvrkyf 163
                 + +++ +li+ D +D+     +q e+       s+ i++  +    +l+t+r  +l++l+e+l      ++e    s++++++rk+ 
  EEA19454.1 452 KTENKHWLIIfDNVDRDY---QQ-ENDINAYSVSNYIPE--VDHGLILITTRLANLQHLGETL------QLETVDMSQAQAIFRKWY 526
                 999888866515555555...55.344555567788888..8888888888888885555555......556777888888888886 PP

>> TPR_6  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.2      0.19        81       1      30 [.     759     788 ..     759     790 .. 0.91
   2 ?    6.7   0.4     0.029        13       5      30 ..     805     830 ..     805     832 .. 0.91
   3 ?    5.8   0.3     0.055        24       5      27 ..     847     869 ..     847     870 .. 0.92
   4 ?    4.7   0.3      0.13        56       5      30 ..     889     914 ..     889     916 .. 0.91
   5 ?    6.4   0.4     0.037        16       5      27 ..     931     953 ..     931     954 .. 0.92
   6 ?    3.4   0.2      0.32   1.4e+02       5      27 ..     973     995 ..     973     996 .. 0.92
   7 ?    6.6   0.2     0.032        14       5      30 ..    1015    1040 ..    1015    1042 .. 0.92
   8 ?    4.4   0.2      0.16        69       5      27 ..    1057    1079 ..    1057    1080 .. 0.92
   9 ?    1.0   0.2         2   8.7e+02       6      28 ..    1100    1122 ..    1099    1126 .. 0.85
  10 ?    3.2   0.1      0.39   1.7e+02       5      27 ..    1141    1163 ..    1141    1164 .. 0.91
  11 ?    4.7   0.3      0.13        56       5      30 ..    1183    1208 ..    1183    1210 .. 0.91
  12 ?    7.9   0.5     0.012       5.3       5      30 ..    1225    1250 ..    1225    1252 .. 0.92
  13 ?   -0.7   0.3       6.9     3e+03       5      28 ..    1271    1294 ..    1269    1296 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.19
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHH- CS
       TPR_6   1 dAlyklalsyrklgdtdkAlealerlikeY 30 
                 +Al +++ ++   g+  kA ++++r ++ Y
  EEA19454.1 759 YALHMMGILLSDRGNLGKAEKMYQRALEGY 788
                 79*********988***********99866 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.029
                 HHHHHHHHHHHHHHHHHHHHHHHHH- CS
       TPR_6   5 klalsyrklgdtdkAlealerlikeY 30 
                 +l+l+y  +g+ ++A ++++r ++ Y
  EEA19454.1 805 NLGLLYADQGKLTDAEKMYQRALEGY 830
                 59*******************99866 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.055
                 HHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   5 klalsyrklgdtdkAlealerli 27 
                 +l+ +y+++g+ ++A ++++r +
  EEA19454.1 847 NLGNLYKNQGKLADAEKMYQRAL 869
                 5899*****************87 PP

  == domain 4  score: 4.7 bits;  conditional E-value: 0.13
                 HHHHHHHHHHHHHHHHHHHHHHHHH- CS
       TPR_6   5 klalsyrklgdtdkAlealerlikeY 30 
                 +l+l+y  +g+  +A ++++r ++ Y
  EEA19454.1 889 NLGLLYADQGKLVDAEKMYQRALEGY 914
                 59*******9***********99866 PP

  == domain 5  score: 6.4 bits;  conditional E-value: 0.037
                 HHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   5 klalsyrklgdtdkAlealerli 27 
                 +l+l+y  +g+ ++A ++++r +
  EEA19454.1 931 NLGLLYADQGKLEDAEKMYQRAL 953
                 59*******************87 PP

  == domain 6  score: 3.4 bits;  conditional E-value: 0.32
                 HHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   5 klalsyrklgdtdkAlealerli 27 
                 +l+l+y  +g+  +A ++++r +
  EEA19454.1 973 NLGLLYADQGKLVDAEKMYQRAL 995
                 59******************987 PP

  == domain 7  score: 6.6 bits;  conditional E-value: 0.032
                  HHHHHHHHHHHHHHHHHHHHHHHHH- CS
       TPR_6    5 klalsyrklgdtdkAlealerlikeY 30  
                  +l+l+y ++g+ ++A ++++r ++ Y
  EEA19454.1 1015 NLGLLYTNQGKLTDAEKMYQRALEGY 1040
                  69*******************99866 PP

  == domain 8  score: 4.4 bits;  conditional E-value: 0.16
                  HHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6    5 klalsyrklgdtdkAlealerli 27  
                  +l+l+y ++g+  +A +++++ +
  EEA19454.1 1057 NLGLLYANQGKLVDAEKMYQQAL 1079
                  69******************987 PP

  == domain 9  score: 1.0 bits;  conditional E-value: 2
                  HHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6    6 lalsyrklgdtdkAlealerlik 28  
                  l+ +y  +g+ ++A ++++  ++
  EEA19454.1 1100 LGNLYAGQGKLTDAEKMYQLALE 1122
                  899999999*********98776 PP

  == domain 10  score: 3.2 bits;  conditional E-value: 0.39
                  HHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6    5 klalsyrklgdtdkAlealerli 27  
                  +l+ +y  +g+ ++A ++++r +
  EEA19454.1 1141 NLGNLYVDQGKLTDAEKMYQRAL 1163
                  58999****************87 PP

  == domain 11  score: 4.7 bits;  conditional E-value: 0.13
                  HHHHHHHHHHHHHHHHHHHHHHHHH- CS
       TPR_6    5 klalsyrklgdtdkAlealerlikeY 30  
                  +l+l+y  +g+  +A ++++r ++ Y
  EEA19454.1 1183 NLGLLYADQGKLVDAEKMYQRALEGY 1208
                  59*******9***********99866 PP

  == domain 12  score: 7.9 bits;  conditional E-value: 0.012
                  HHHHHHHHHHHHHHHHHHHHHHHHH- CS
       TPR_6    5 klalsyrklgdtdkAlealerlikeY 30  
                  +l+l+y  +g+ ++A ++++r ++ Y
  EEA19454.1 1225 NLGLLYADQGKLEDAEKLYQRALEGY 1250
                  59*******************99866 PP

  == domain 13  score: -0.7 bits;  conditional E-value: 6.9
                  HHHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6    5 klalsyrklgdtdkAlealerlik 28  
                    +++++  g+ ++A+ ++ r ++
  EEA19454.1 1271 SYGMLLEDKGRLRDAKLMYTRALS 1294
                  5688888878*******9999876 PP

>> GHL13  Hypothetical glycosyl hydrolase family 13
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   0.0    0.0082       3.6     123     173 ..     742     793 ..     708     805 .. 0.75
   2 ?    2.2   0.0      0.18        78     146     174 ..     807     836 ..     800     857 .. 0.84
   3 ?    0.2   0.0      0.73   3.2e+02     146     173 ..     891     919 ..     884     937 .. 0.86
   4 ?   -2.2   0.0       3.7   1.6e+03     146     171 ..     933     958 ..     922     967 .. 0.83
   5 ?   -0.5   0.0       1.1     5e+02     146     173 ..    1017    1045 ..    1008    1058 .. 0.85
   6 ?    0.0   0.0       0.8   3.5e+02     146     173 ..    1185    1213 ..    1179    1225 .. 0.86
   7 ?    0.1   0.0      0.74   3.2e+02     146     173 ..    1227    1254 ..    1215    1265 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.0082
                 TSHHHHHHHHHHHHHHHHH---SEEEE-TT----TT---SHHHHHHHHH.TT CS
       GHL13 123 fspearklikeiYedlaaaakfdGiLfhddavlsdfEdaseaalaaykk.ag 173
                  ++ +  +++e+ e+++ a ++ GiL++d   l   E   ++al+ y+k +g
  EEA19454.1 742 MERATADTMTEVNEEVSYALHMMGILLSDRGNLGKAEKMYQRALEGYEKaWG 793
                 45566778999************************************98344 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.18
                 EEEE-TT----TT---SHHHHHHHHH.TT- CS
       GHL13 146 GiLfhddavlsdfEdaseaalaaykk.agl 174
                 G+L+ d+  l+d E   ++al+ y+k +g 
  EEA19454.1 807 GLLYADQGKLTDAEKMYQRALEGYEKaWGS 836
                 9***********************985654 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.73
                 EEEE-TT----TT---SHHHHHHHHH.TT CS
       GHL13 146 GiLfhddavlsdfEdaseaalaaykk.ag 173
                 G+L+ d+  l d E   ++al+ y+k +g
  EEA19454.1 891 GLLYADQGKLVDAEKMYQRALEGYEKaWG 919
                 9***********************98444 PP

  == domain 4  score: -2.2 bits;  conditional E-value: 3.7
                 EEEE-TT----TT---SHHHHHHHHH CS
       GHL13 146 GiLfhddavlsdfEdaseaalaaykk 171
                 G+L+ d+  l+d E   ++al+  ++
  EEA19454.1 933 GLLYADQGKLEDAEKMYQRALEGKET 958
                 9**************99999986554 PP

  == domain 5  score: -0.5 bits;  conditional E-value: 1.1
                  EEEE-TT----TT---SHHHHHHHHH.TT CS
       GHL13  146 GiLfhddavlsdfEdaseaalaaykk.ag 173 
                  G+L+ ++  l+d E   ++al+ y+k +g
  EEA19454.1 1017 GLLYTNQGKLTDAEKMYQRALEGYEKaWG 1045
                  9***********************98344 PP

  == domain 6  score: 0.0 bits;  conditional E-value: 0.8
                  EEEE-TT----TT---SHHHHHHHHH.TT CS
       GHL13  146 GiLfhddavlsdfEdaseaalaaykk.ag 173 
                  G+L+ d+  l d E   ++al+ y+k +g
  EEA19454.1 1185 GLLYADQGKLVDAEKMYQRALEGYEKaWG 1213
                  9***********************98344 PP

  == domain 7  score: 0.1 bits;  conditional E-value: 0.74
                  EEEE-TT----TT---SHHHHHHHHHTT CS
       GHL13  146 GiLfhddavlsdfEdaseaalaaykkag 173 
                  G+L+ d+  l+d E   ++al+ y+ka 
  EEA19454.1 1227 GLLYADQGKLEDAEKLYQRALEGYEKAL 1254
                  9***********************9865 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   0.00017     0.073       1      25 [.     368     394 ..     368     465 .. 0.75

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 0.00017
      AAA_33   1 lvllvGlpGsGKstlaerllkklg..a 25 
                 +v+l+Gl G GK++la + ++k++  +
  EEA19454.1 368 VVVLHGLGGIGKTQLAAEFARKHQaaF 394
                 89********************99541 PP

>> DUF5344  Family of unknown function (DUF5344)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.0     0.088        38      44      78 ..     815     849 ..     811     856 .. 0.92
   2 ?    0.2   0.0       2.7   1.2e+03      44      77 ..    1025    1058 ..    1019    1060 .. 0.87
   3 ?   -1.0   0.0       6.2   2.7e+03      43      76 ..    1108    1141 ..    1089    1144 .. 0.78
   4 ?   -1.5   0.0         9   3.9e+03      44      77 ..    1193    1226 ..    1191    1228 .. 0.82

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.088
     DUF5344  44 kineleeeleellkaYktlllknvedtesaVdslk 78 
                 k+++ e+ ++ +l+ Y+++  +n + t + V++l+
  EEA19454.1 815 KLTDAEKMYQRALEGYEKAWGSNHTSTLDTVNNLG 849
                 78999***************************997 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 2.7
     DUF5344   44 kineleeeleellkaYktlllknvedtesaVdsl 77  
                  k+++ e+ ++ +l+ Y+++   + + t + V++l
  EEA19454.1 1025 KLTDAEKMYQRALEGYEKAWGPDHTSTLDTVNNL 1058
                  78999************99998888888888877 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 6.2
     DUF5344   43 ekineleeeleellkaYktlllknvedtesaVds 76  
                   k+++ e+ ++ +l+ Y+++l  +   t   V++
  EEA19454.1 1108 GKLTDAEKMYQLALEGYEKALGPDHISTLGIVNN 1141
                  5889999**********99997666666655555 PP

  == domain 4  score: -1.5 bits;  conditional E-value: 9
     DUF5344   44 kineleeeleellkaYktlllknvedtesaVdsl 77  
                  k+ + e+ ++ +l+ Y+++   + + t + V++l
  EEA19454.1 1193 KLVDAEKMYQRALEGYEKAWGPDHTSTLDTVNNL 1226
                  5667899999999999999988888888888876 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00031      0.13       2      80 ..     366     472 ..     365     489 .. 0.71

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00031
      AAA_14   2 rkilvitGaRrvGKTtllkqlikellvkkesilyinldderd........................kkladpe.......kllelileklke..ekkty 67 
                 ++++v+ G+  +GKT l+ ++++++ +   s++ ++  +e+                         +     +        +++ ++e l++  +k+ +
  EEA19454.1 366 QQVVVLHGLGGIGKTQLAAEFARKHQAAFTSVFWLDGSSEDSlkqsiadysgripegqipetsrkyS-----SsangdlkAVINDFMEWLSKteNKHWL 459
                 589***********************88889999998888886677777777777777766654331.....022333446667777764334577778 PP

      AAA_14  68 lflDEiqevpewe 80 
                 +++D + +  + e
  EEA19454.1 460 IIFDNVDRDYQQE 472
                 9999887765555 PP

>> DUF4810  Domain of unknown function (DUF4810)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.2       2.3     1e+03      23      71 ..     736     784 ..     718     791 .. 0.65
   2 ?    3.8   0.1      0.19        82      50      72 ..     805     827 ..     802     833 .. 0.86
   3 ?    0.0   0.1         3   1.3e+03      50      70 ..     847     867 ..     844     875 .. 0.89
   4 ?    2.8   0.1      0.41   1.8e+02      50      72 ..     889     911 ..     886     917 .. 0.85
   5 ?    4.4   0.1      0.13        55      50      70 ..     931     951 ..     928     955 .. 0.90
   6 ?    2.0   0.1      0.69     3e+02      50      70 ..     973     993 ..     970     999 .. 0.89
   7 ?    3.3   0.1      0.28   1.2e+02      50      72 ..    1015    1037 ..    1012    1043 .. 0.86
   8 ?    2.9   0.1      0.36   1.6e+02      50      70 ..    1057    1077 ..    1054    1080 .. 0.90
   9 ?   -0.6   0.1       4.6     2e+03      50      70 ..    1099    1119 ..    1097    1128 .. 0.85
  10 ?    2.4   0.0      0.55   2.4e+02      46      70 ..    1137    1161 ..    1135    1164 .. 0.91
  11 ?    2.8   0.1      0.41   1.8e+02      50      72 ..    1183    1205 ..    1180    1211 .. 0.85
  12 ?    4.7   0.1     0.098        43      50      72 ..    1225    1247 ..    1222    1253 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 2.3
     DUF4810  23 ekqieklekii.ekaeakgkkvpPGlyAelGllylkegkkeeaieafekE 71 
                 e+ ie++e++  +++ + +++v   l+  +G+l++++g+  +a +++++ 
  EEA19454.1 736 ESCIERMERATaDTMTEVNEEVSYALH-MMGILLSDRGNLGKAEKMYQRA 784
                 555555554431344555555554444.489************9999975 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.19
     DUF4810  50 elGllylkegkkeeaieafekEk 72 
                 +lGlly+++gk  +a +++++  
  EEA19454.1 805 NLGLLYADQGKLTDAEKMYQRAL 827
                 79***************999755 PP

  == domain 3  score: 0.0 bits;  conditional E-value: 3
     DUF4810  50 elGllylkegkkeeaieafek 70 
                 +lG ly ++gk ++a +++++
  EEA19454.1 847 NLGNLYKNQGKLADAEKMYQR 867
                 79*************999985 PP

  == domain 4  score: 2.8 bits;  conditional E-value: 0.41
     DUF4810  50 elGllylkegkkeeaieafekEk 72 
                 +lGlly+++gk  +a +++++  
  EEA19454.1 889 NLGLLYADQGKLVDAEKMYQRAL 911
                 79**************9999755 PP

  == domain 5  score: 4.4 bits;  conditional E-value: 0.13
     DUF4810  50 elGllylkegkkeeaieafek 70 
                 +lGlly+++gk e+a +++++
  EEA19454.1 931 NLGLLYADQGKLEDAEKMYQR 951
                 79**************99985 PP

  == domain 6  score: 2.0 bits;  conditional E-value: 0.69
     DUF4810  50 elGllylkegkkeeaieafek 70 
                 +lGlly+++gk  +a +++++
  EEA19454.1 973 NLGLLYADQGKLVDAEKMYQR 993
                 79***********99999985 PP

  == domain 7  score: 3.3 bits;  conditional E-value: 0.28
     DUF4810   50 elGllylkegkkeeaieafekEk 72  
                  +lGlly ++gk  +a +++++  
  EEA19454.1 1015 NLGLLYTNQGKLTDAEKMYQRAL 1037
                  79***************999755 PP

  == domain 8  score: 2.9 bits;  conditional E-value: 0.36
     DUF4810   50 elGllylkegkkeeaieafek 70  
                  +lGlly+++gk  +a +++++
  EEA19454.1 1057 NLGLLYANQGKLVDAEKMYQQ 1077
                  79*************999986 PP

  == domain 9  score: -0.6 bits;  conditional E-value: 4.6
     DUF4810   50 elGllylkegkkeeaieafek 70  
                  +lG ly+ +gk  +a ++++ 
  EEA19454.1 1099 NLGNLYAGQGKLTDAEKMYQL 1119
                  69*************999985 PP

  == domain 10  score: 2.4 bits;  conditional E-value: 0.55
     DUF4810   46 GlyAelGllylkegkkeeaieafek 70  
                  G+  +lG ly+++gk  +a +++++
  EEA19454.1 1137 GIVNNLGNLYVDQGKLTDAEKMYQR 1161
                  88899**************999985 PP

  == domain 11  score: 2.8 bits;  conditional E-value: 0.41
     DUF4810   50 elGllylkegkkeeaieafekEk 72  
                  +lGlly+++gk  +a +++++  
  EEA19454.1 1183 NLGLLYADQGKLVDAEKMYQRAL 1205
                  79**************9999755 PP

  == domain 12  score: 4.7 bits;  conditional E-value: 0.098
     DUF4810   50 elGllylkegkkeeaieafekEk 72  
                  +lGlly+++gk e+a + +++  
  EEA19454.1 1225 NLGLLYADQGKLEDAEKLYQRAL 1247
                  79***************999755 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.0    0.0015      0.64       3      75 ..     367     466 ..     365     475 .. 0.73
   2 ?    0.1   0.1       1.3   5.8e+02      68     124 ..     797     854 ..     724     890 .. 0.73
   3 ?   -2.2   0.0       6.5   2.8e+03      24     105 ..     963    1045 ..     943    1062 .. 0.61

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0015
      AAA_24   3 lkiliyGpsgiGKTtlakel..gpkplfi.......dtekGlksldadkfpdie.................swedfldevvel.aaeladyktlviDti 74 
                 + +++ G  giGKT la+e+  + +++f          e++lk+  ad   +i+                  ++++++++ e+ ++ +++   +++D++
  EEA19454.1 367 QVVVLHGLGGIGKTQLAAEFarKHQAAFTsvfwldgSSEDSLKQSIADYSGRIPegqipetsrkysssangDLKAVINDFMEWlSKTENKHWLIIFDNV 465
                 6899****************9855555556677777778888888888888888888888888887776665555554444446666666777777777 PP

      AAA_24  75 d 75 
                 d
  EEA19454.1 466 D 466
                 7 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 1.3
      AAA_24  68 tlviDtideleelclaev.irqnekaeskedkgdgkGygelaeefrrllkklqelrkn 124
                 t  +Dt++ l  l  ++   + +ek++++   g+ k++g   +   +++++l +l kn
  EEA19454.1 797 TSTLDTVNNLGLLYADQGkLTDAEKMYQRALEGYEKAWGSNHTSTLDTVNNLGNLYKN 854
                 5556777777666666654566677777777888888988888888888888877664 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 6.5
      AAA_24   24 pkplfidtekGlksldadkfpdieswedfldevvelaaeladyktlviDtideleelclaev.irqnekaeskedkgdgkGyg 105 
                  +++l +dt + l  l+ad+++ + + ++   +++  ++++ + +t  +Dt++ l  l +++   + +ek++++   g+ k++g
  EEA19454.1  963 DHTLTLDTVNNLGLLYADQGKLVDAEKMYQRALEGKEKAWGPDHTSTLDTVNNLGLLYTNQGkLTDAEKMYQRALEGYEKAWG 1045
                  55666666665555666666655555555555555566666666667777777766666666445555556665555666665 PP

>> CBP_BcsQ  Cellulose biosynthesis protein BcsQ
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0    0.0012      0.51       2      45 ..     367     409 ..     366     415 .. 0.93
   2 ?   -1.0   0.1       2.3     1e+03     169     202 ..     603     636 ..     590     657 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.0012
    CBP_BcsQ   2 kvlalqGvRGGvGttsllaaLawalhelgesvlviDlspdnlLr 45 
                 +v++l+G+ GG+G+t l+a  a+  ++   sv  +D s+++ L+
  EEA19454.1 367 QVVVLHGL-GGIGKTQLAAEFARKHQAAFTSVFWLDGSSEDSLK 409
                 5899***9.9*****************************99987 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 2.3
    CBP_BcsQ 169 NqfeaasqlqqDllqlWlqslrrllPlvihrDea 202
                 N  +a+ + +  ll+lW +  ++ lP  i +  a
  EEA19454.1 603 NAIRAKDEAAANLLLLWAHLDHKTLPFWILQAGA 636
                 777888888999**************98866555 PP

>> DUF4388  Domain of unknown function (DUF4388)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.0       2.3     1e+03      31      46 ..     888     903 ..     799     949 .. 0.72
   2 ?    3.6   0.0      0.19        81      49      49 ..    1032    1032 ..     961    1247 .. 0.68

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 2.3
     DUF4388  31 geeariffrdGrivyA 46 
                 ++ + ++  +G++v A
  EEA19454.1 888 NNLGLLYADQGKLVDA 903
                 3345566666666666 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.19
     DUF4388   49 l 49  
                  +
  EEA19454.1 1032 M 1032
                  0 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00061      0.27       1      74 [.     369     472 ..     369     488 .. 0.66

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00061
                 EEEESSTTSSHHHHHHHHHHHHTHE...EEEEETTTCSSS.......................STTHHHHHHHHHHHHH.....HHTS.TSEEEEEETG CS
         AAA   1 vllyGppGtGKTllakavakelgve...fleisgsellsk.......................yvgesekkirelfkea.....keka.kpsilfiDEi 67 
                 v+l+G  G+GKT la   a++ ++    ++ ++gs+   +                       y + ++ ++++++++      k+ + k+  +++D++
  EEA19454.1 369 VVLHGLGGIGKTQLAAEFARKHQAAftsVFWLDGSSED-SlkqsiadysgripegqipetsrkYSSSANGDLKAVINDFmewlsKT-EnKHWLIIFDNV 465
                 689******************76542223333333333.13456666666666666666666677777777777777753333333.257899999*99 PP

                 GGHHHHH CS
         AAA  68 dalaksr 74 
                 d+  +++
  EEA19454.1 466 DRDYQQE 472
                 9866555 PP

>> DUF1754  Eukaryotic family of unknown function (DUF1754)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.2      0.22        95      73      95 ..     808     830 ..     776     833 .. 0.77
   2 ?    4.1   0.1      0.19        82      60      95 ..    1005    1040 ..     977    1043 .. 0.73
   3 ?    4.4   0.0      0.15        65      62      95 ..    1091    1124 ..    1063    1127 .. 0.74
   4 ?    3.0   0.0      0.42   1.8e+02      76      93 ..    1147    1164 ..    1134    1168 .. 0.86

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.22
     DUF1754  73 ekeeeqenlTeAErkfeevrkKr 95 
                    ++q +lT AE+ ++ +++ +
  EEA19454.1 808 LLYADQGKLTDAEKMYQRALEGY 830
                 5567899**********998755 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.19
     DUF1754   60 dkeeeeddseekkekeeeqenlTeAErkfeevrkKr 95  
                  d+ ++ d  ++      +q +lT AE+ ++ +++ +
  EEA19454.1 1005 DHTSTLDTVNNLGLLYTNQGKLTDAEKMYQRALEGY 1040
                  55555566666666667899**********998755 PP

  == domain 3  score: 4.4 bits;  conditional E-value: 0.15
     DUF1754   62 eeeeddseekkekeeeqenlTeAErkfeevrkKr 95  
                   ++ d  ++  +  + q +lT AE+ ++++++ +
  EEA19454.1 1091 TSTLDTVNNLGNLYAGQGKLTDAEKMYQLALEGY 1124
                  555556666666677899**********998755 PP

  == domain 4  score: 3.0 bits;  conditional E-value: 0.42
     DUF1754   76 eeqenlTeAErkfeevrk 93  
                  ++q +lT AE+ ++ +++
  EEA19454.1 1147 VDQGKLTDAEKMYQRALE 1164
                  67899*********9875 PP

>> TniB  Bacterial TniB protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.0    0.0021      0.92      32      62 ..     363     393 ..     340     397 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0021
        TniB  32 rkrmpnlllvGdsnnGKtmivekFarlhppe 62 
                   r + ++l+G   +GKt+++ +Far+h+++
  EEA19454.1 363 DYRQQVVVLHGLGGIGKTQLAAEFARKHQAA 393
                 56889999********************976 PP

>> MIT  MIT (microtubule interacting and transport) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0       1.3   5.5e+02      17      30 ..     778     791 ..     766     793 .. 0.62
   2 ?    4.2   0.1      0.11        47       8      30 ..     811     833 ..     806     836 .. 0.81
   3 ?    0.5   0.3       1.5   6.5e+02      16      32 ..     854     870 ..     851     873 .. 0.88
   4 ?    3.2   0.1      0.22        96      13      30 ..     900     917 ..     891     919 .. 0.80
   5 ?    1.5   0.1      0.73   3.2e+02      16      32 ..     938     954 ..     932     955 .. 0.81
   6 ?   -1.5   0.1       6.1   2.7e+03      17      32 ..     981     996 ..     976     997 .. 0.80
   7 ?    4.0   0.1      0.12        51       9      30 ..    1022    1043 ..    1017    1045 .. 0.80
   8 ?    1.8   0.1       0.6   2.6e+02      14      32 ..    1062    1080 ..    1057    1086 .. 0.87
   9 ?    4.1   0.3      0.11        49      14      31 ..    1111    1128 ..    1104    1129 .. 0.86
  10 ?   -0.8   0.0       3.8   1.6e+03      17      32 ..    1149    1164 ..    1148    1176 .. 0.81
  11 ?    3.2   0.1      0.22        96      13      30 ..    1194    1211 ..    1185    1213 .. 0.80
  12 ?    7.7   0.2    0.0086       3.8       7      31 ..    1230    1254 ..    1226    1256 .. 0.84

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 1.3
         MIT  17 agnyeeAlelYkea 30 
                 ++ y+ Ale Y++a
  EEA19454.1 778 EKMYQRALEGYEKA 791
                 34456666666555 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.11
         MIT   8 vkkAveeDnagnyeeAlelYkea 30 
                 + +    D ++ y+ Ale Y++a
  EEA19454.1 811 ADQGKLTDAEKMYQRALEGYEKA 833
                 556667799999********998 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 1.5
         MIT  16 nagnyeeAlelYkeale 32 
                 n+g+ ++A ++Y+ ale
  EEA19454.1 854 NQGKLADAEKMYQRALE 870
                 78999999999999997 PP

  == domain 4  score: 3.2 bits;  conditional E-value: 0.22
         MIT  13 eeDnagnyeeAlelYkea 30 
                   D ++ y+ Ale Y++a
  EEA19454.1 900 LVDAEKMYQRALEGYEKA 917
                 56999999*****99998 PP

  == domain 5  score: 1.5 bits;  conditional E-value: 0.73
         MIT  16 nagnyeeAlelYkeale 32 
                  +g+ e+A ++Y+ ale
  EEA19454.1 938 DQGKLEDAEKMYQRALE 954
                 56889999999999987 PP

  == domain 6  score: -1.5 bits;  conditional E-value: 6.1
         MIT  17 agnyeeAlelYkeale 32 
                 +g+  +A ++Y+ ale
  EEA19454.1 981 QGKLVDAEKMYQRALE 996
                 5788889999999987 PP

  == domain 7  score: 4.0 bits;  conditional E-value: 0.12
         MIT    9 kkAveeDnagnyeeAlelYkea 30  
                  ++    D ++ y+ Ale Y++a
  EEA19454.1 1022 NQGKLTDAEKMYQRALEGYEKA 1043
                  5566679999999999999998 PP

  == domain 8  score: 1.8 bits;  conditional E-value: 0.6
         MIT   14 eDnagnyeeAlelYkeale 32  
                  + n+g+  +A ++Y++ale
  EEA19454.1 1062 YANQGKLVDAEKMYQQALE 1080
                  56899999999*****997 PP

  == domain 9  score: 4.1 bits;  conditional E-value: 0.11
         MIT   14 eDnagnyeeAlelYkeal 31  
                   D ++ y+ Ale Y++al
  EEA19454.1 1111 TDAEKMYQLALEGYEKAL 1128
                  6999************98 PP

  == domain 10  score: -0.8 bits;  conditional E-value: 3.8
         MIT   17 agnyeeAlelYkeale 32  
                  +g+  +A ++Y+ ale
  EEA19454.1 1149 QGKLTDAEKMYQRALE 1164
                  5788899999999998 PP

  == domain 11  score: 3.2 bits;  conditional E-value: 0.22
         MIT   13 eeDnagnyeeAlelYkea 30  
                    D ++ y+ Ale Y++a
  EEA19454.1 1194 LVDAEKMYQRALEGYEKA 1211
                  56999999*****99998 PP

  == domain 12  score: 7.7 bits;  conditional E-value: 0.0086
         MIT    7 lvkkAveeDnagnyeeAlelYkeal 31  
                  ++ +   eD ++ y+ Ale Y++al
  EEA19454.1 1230 YADQGKLEDAEKLYQRALEGYEKAL 1254
                  5677788999************998 PP

>> APS_kinase  Adenylylsulphate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   0.0    0.0063       2.8       3      39 ..     367     403 ..     365     414 .. 0.91
   2 ?   -0.7   0.0       2.7   1.2e+03     114     133 ..    1150    1169 ..    1143    1174 .. 0.84

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0063
                 EEEEEESSTTSSHHHHHHHHHHHHHHTT--EEEEEHH CS
  APS_kinase   3 vvvwltGlsgsGKstianalekkLvekgisvylLdGd 39 
                  vv l Gl g GK+ +a ++++k ++  +sv  LdG 
  EEA19454.1 367 QVVVLHGLGGIGKTQLAAEFARKHQAAFTSVFWLDGS 403
                 6899*******************************96 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 2.7
                  HHHHTTTSHHHHHHTTSSSS CS
  APS_kinase  114 ceerDpkglYkkareGeike 133 
                   + +D   +Y++a eG++k 
  EEA19454.1 1150 GKLTDAEKMYQRALEGKVKA 1169
                  5668999**********996 PP

>> TPR_3  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.1       9.5   4.2e+03       6      16 ..     719     729 ..     719     729 .. 0.88
   2 ?    4.1   0.0      0.11        47       7      25 ..     806     824 ..     801     827 .. 0.91
   3 ?   -0.8   0.4       3.7   1.6e+03      13      25 ..     854     866 ..     851     868 .. 0.92
   4 ?    0.3   0.0       1.7   7.3e+02       7      25 ..     890     908 ..     886     911 .. 0.91
   5 ?    3.5   0.1      0.16        72       7      25 ..     932     950 ..     930     953 .. 0.91
   6 ?    0.3   0.0       1.7   7.4e+02       7      25 ..     974     992 ..     971     995 .. 0.91
   7 ?    1.8   0.0      0.59   2.6e+02      10      25 ..    1019    1034 ..    1015    1037 .. 0.83
   8 ?    3.9   0.1      0.13        55       7      29 ..    1058    1078 ..    1053    1080 .. 0.89
   9 ?    3.1   0.1      0.23     1e+02      11      30 ..    1104    1121 ..    1099    1122 .. 0.83
  10 ?   -0.5   0.1       2.9   1.3e+03      13      25 ..    1148    1160 ..    1144    1162 .. 0.91
  11 ?    0.3   0.0       1.7   7.3e+02       7      25 ..    1184    1202 ..    1180    1205 .. 0.91
  12 ?    6.4   0.1     0.021         9       7      25 ..    1226    1244 ..    1221    1247 .. 0.92

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 9.5
                 HHHHHHHHTT- CS
       TPR_3   6 syAaefynkkk 16 
                 ++A e+++k++
  EEA19454.1 719 KHATEYHQKQR 729
                 69******985 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.11
                 HHHHHHHTT-HHHHHHH.. CS
       TPR_3   7 yAaefynkkkyqeArelfs 25 
                 ++  + +++k+++A+  ++
  EEA19454.1 806 LGLLYADQGKLTDAEKMYQ 824
                 68899***********988 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 3.7
                 HTT-HHHHHHH.. CS
       TPR_3  13 nkkkyqeArelfs 25 
                 n++k+ +A+  ++
  EEA19454.1 854 NQGKLADAEKMYQ 866
                 89********988 PP

  == domain 4  score: 0.3 bits;  conditional E-value: 1.7
                 HHHHHHHTT-HHHHHHH.. CS
       TPR_3   7 yAaefynkkkyqeArelfs 25 
                 ++  + +++k+ +A+  ++
  EEA19454.1 890 LGLLYADQGKLVDAEKMYQ 908
                 68899**********9988 PP

  == domain 5  score: 3.5 bits;  conditional E-value: 0.16
                 HHHHHHHTT-HHHHHHH.. CS
       TPR_3   7 yAaefynkkkyqeArelfs 25 
                 ++  + +++k+++A+  ++
  EEA19454.1 932 LGLLYADQGKLEDAEKMYQ 950
                 68899***********988 PP

  == domain 6  score: 0.3 bits;  conditional E-value: 1.7
                 HHHHHHHTT-HHHHHHH.. CS
       TPR_3   7 yAaefynkkkyqeArelfs 25 
                 ++  + +++k+ +A+  ++
  EEA19454.1 974 LGLLYADQGKLVDAEKMYQ 992
                 68899**********9988 PP

  == domain 7  score: 1.8 bits;  conditional E-value: 0.59
                  HHHHTT-HHHHHHH.. CS
       TPR_3   10 efynkkkyqeArelfs 25  
                   + n++k+++A+  ++
  EEA19454.1 1019 LYTNQGKLTDAEKMYQ 1034
                  5569*********988 PP

  == domain 8  score: 3.9 bits;  conditional E-value: 0.13
                  HHHHHHHTT-HHHHHHH..HHHH CS
       TPR_3    7 yAaefynkkkyqeArelfsYall 29  
                  ++  + n++k+ +A+  ++  ++
  EEA19454.1 1058 LGLLYANQGKLVDAEKMYQ--QA 1078
                  6889*************88..87 PP

  == domain 9  score: 3.1 bits;  conditional E-value: 0.23
                  HHHTT-HHHHHHH..HHHHH CS
       TPR_3   11 fynkkkyqeArelfsYalla 30  
                  +  ++k+++A+  ++  l+ 
  EEA19454.1 1104 YAGQGKLTDAEKMYQ--LAL 1121
                  5669*********88..985 PP

  == domain 10  score: -0.5 bits;  conditional E-value: 2.9
                  HTT-HHHHHHH.. CS
       TPR_3   13 nkkkyqeArelfs 25  
                  +++k+++A+  ++
  EEA19454.1 1148 DQGKLTDAEKMYQ 1160
                  69********988 PP

  == domain 11  score: 0.3 bits;  conditional E-value: 1.7
                  HHHHHHHTT-HHHHHHH.. CS
       TPR_3    7 yAaefynkkkyqeArelfs 25  
                  ++  + +++k+ +A+  ++
  EEA19454.1 1184 LGLLYADQGKLVDAEKMYQ 1202
                  68899**********9988 PP

  == domain 12  score: 6.4 bits;  conditional E-value: 0.021
                  HHHHHHHTT-HHHHHHH.. CS
       TPR_3    7 yAaefynkkkyqeArelfs 25  
                  ++  + +++k+++A+ l++
  EEA19454.1 1226 LGLLYADQGKLEDAEKLYQ 1244
                  68899************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1346 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       644  (0.0359195); expected 358.6 (0.02)
Passed bias filter:                      554  (0.0308997); expected 358.6 (0.02)
Passed Vit filter:                        98  (0.005466); expected 17.9 (0.001)
Passed Fwd filter:                        43  (0.00239835); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              41  [number of targets reported over threshold]
# CPU time: 1.19u 0.32s 00:00:01.51 Elapsed: 00:00:00.57
# Mc/sec: 7057.37
//
Query:       EEA19455.1  [L=1013]
Description: succinate-semialdehyde dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.3e-155  518.4   0.0   1.7e-155  518.1   0.0    1.1  1  Aldedh          Aldehyde dehydrogenase family
      2e-62  211.7   0.4      3e-62  211.1   0.4    1.3  1  Glyco_hydro_18  Glycosyl hydrolases family 18
    6.5e-12   45.7  17.7    1.4e-11   44.7  17.7    1.6  1  Chitin_bind_1   Chitin recognition protein


Domain annotation for each model (and alignments):
>> Aldedh  Aldehyde dehydrogenase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  518.1   0.0  2.8e-159  1.7e-155       1     461 [.      27     490 ..      27     491 .. 0.98

  Alignments for each domain:
  == domain 1  score: 518.1 bits;  conditional E-value: 2.8e-159
                 EET-SS.SEEEEEETTTCEEEEEEE-B-HHHHHHHHHHHHHHHHHHTTS-HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH---HHHHHHHHHHHHHHHH CS
      Aldedh   1 wveses.etievinPatgeviakvpaataedvdaavaaAkeafkawaklpaeeRaeiLrkaadlleerkeelaeletletGkplaearaeveeaidvlr 98 
                 wv+s++  ++evi+Pat++ +a++p  ta+dv ++v++A+ af+++ak+++++Ra+ + k+ +l++e+k ++a+++t e+Gkp++ea+ ev+ ++  l 
  EEA19455.1  27 WVQSKNgARFEVIDPATDTAWASCPIFTAQDVPQVVETAHVAFEKFAKTSPRQRADWITKWDSLIKENKIDIAKILTHEAGKPIREAEMEVDFSAASLL 125
                 899999677****************************************************************************************** PP

                 HHHHHHHHHSEEEEEEC..TTEEEEEEEEE-SEEEEEE-SSSCCHHHHHHHHHHHHTT-EEEEEE-TTSHHHHHHHHHHHHHTTS-TTSEEE--SS... CS
      Aldedh  99 yyaelaeklegevlpss..egklalvrrePlGvvgaItPWNfPlllaawklapalaaGNtvvlKPaeetplsalllaelfeeaglPkgvlnvvtgs... 192
                 +ya++ae++eg+v++ss  +g+++++ ++P+Gv + + PWNfP++++++k+ palaaG+++++KP++etpls+l+la l+e+ag+P+gv++v+t++   
  EEA19455.1 126 WYAGEAERIEGTVATSSfpPGRRSFTIKQPIGVAVGLLPWNFPISMLLRKIGPALAAGCSMIVKPSPETPLSTLALAYLAEKAGFPPGVITVLTTDldn 224
                 ***********99888667**************************************************************************886555 PP

                 TCCHHHHHHH-TTESEEEEES-HHHHHHHHHHHHCTTSEEEEEE---EEEEE-TTSHHHHHHHHHHHHHHGGGGTSTTSEEEEEEEHHHHHHHHHHHHH CS
      Aldedh 193 gsevgealvehpevdkvsftGstevgrkiakaaaknlkrvtlElGGknplivledaDldkaveaivkgafgnaGQvCiaasrllvqesiydefveklve 291
                  s+++eal++hp v+kv+ftGst+vg+ ia+++a+ +k+vtlElGG++p iv++da+l +a++++ +  ++naGQ Ci+++r++vq+++y++f e ++e
  EEA19455.1 225 TSSLSEALCKHPLVRKVTFTGSTRVGKIIAAHCAEGIKKVTLELGGNSPYIVFDDANLVQAAMSLTMLKWMNAGQACISPNRVYVQSGVYEKFAEVVKE 323
                 88999********************************************************************************************** PP

                 HHHT--BS-TTSTT-SB---SSHHHHHHHHHHHHHHHHTTSEEEE-TTE.SB-SSSTTEE--EEEES-TTTSHHHHS---SSEEEEEEESSHHHHHHHH CS
      Aldedh 292 aakklkvgdpldedtdvGPliseaqlekvekyveeakeegaklllGgereeaglekgyfvePtvlanvtpdmriaqeEiFGPVlsvikfkdeeeaieia 390
                 +a+k+ vg + ++dt++GPl+s++ l+kv +++++a++ gak+llGg  ++  +  gyfvePtv++++tp+m i +eE F+PVl+++kf++eee+ ++a
  EEA19455.1 324 HASKIVVGPGSAPDTTMGPLTSPRGLDKVLNQINDATKLGAKILLGG--HRVPNTPGYFVEPTVIKDMTPEMLISREESFAPVLALYKFETEEEVTKLA 420
                 ***********************************************..5578899******************************************* PP

                 HSSSEESEEEEE-SBHHHHHHHHHHS-SSEEEESSSST--TTTSEB--CGGGEES-BSHHHHHHHTEEEEE CS
      Aldedh 391 NdteyGLaagvftkdleraervaerleaGnvyiNdsttgaaealpfgGvkqSglGreggkegleeytevkt 461
                 Ndt +GLa++vftk+++r+ r+ e+leaG+v++N+ + ++ e+ pfgG k+Sg+G+e+gk+g+eey+ +kt
  EEA19455.1 421 NDTSMGLASYVFTKNVDRIWRMFENLEAGMVGLNSGQPSTLET-PFGGTKESGYGKEQGKHGIEEYLITKT 490
                 *****************************************99.***********************9997 PP

>> Glyco_hydro_18  Glycosyl hydrolases family 18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  211.1   0.4   5.1e-66     3e-62       2     311 ..     674    1001 ..     673    1002 .. 0.91

  Alignments for each domain:
  == domain 1  score: 211.1 bits;  conditional E-value: 5.1e-66
                      EEEEEEGGGGGSS.G.C....SHTTTESEEEEEEEEEEETTTEEEESSTTHHHHHHHHHHHH.HHTSTT-EEEEEEEETTT.TTHHHHHHTSH CS
                      xxxxxxxxxxxxx.x.x....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxx.xxxxxxxxxxx RF
  Glyco_hydro_18    2 vvgYysswesygn.n.y....lpsaklthiiyaFakidgengkvvvsdwedlgnfeqlkklk.kkknpgvkvllsiGGwtd.ssgfslaastd 86  
                       ++Yy+sw+s++  n y    ++++ +thi++aFa id+ +g+v +s ++d+  f qlk+ + k ++ +v +++++GG++  s++f+++a+t+
      EEA19455.1  674 SIAYYESWASHRVcNnYmpsdIDPTPYTHINFAFALIDN-DGEVMLSLSNDTILFDQLKDVRdKSQAGDVELWIAVGGYAVgSAPFAKLAATQ 765 
                      689********988776677788**************98.98999776888899**************************6599********* PP

                      HHHHHHHHHHHHHHHHCT-SEEEEEES-TTTS.....TCHHHHHHHHHHHHHHHHHHHHHHTSTTCEEEEEEESSHHHHHHHCHHHHHHHHTS CS
                      xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18   87 asrkkfadsvvsllrkygfDGiDidweypggn.....pedkenytallkelrealdkakategkkllLsaavpasasdlskgydlpkiakylD 174 
                      + rk+f+ds+ ++++kygf G D+dweyp ++     ++d +n+  l+ke r +++        ++ Ls++vp++  + +kg dl+ i  y+D
      EEA19455.1  766 QGRKTFIDSACAFMDKYGFKGMDLDWEYPAATetggtTADTANMISLVKEYRDKCK--------NKGLSVTVPGGTFY-MKGFDLKGIEPYVD 849 
                      ****************************998899999999*************776........567*******9999.6677********** PP

                      EEEEETTTSSSTTSS..BE--SS-SSBTCSSHHHHHHHHHHTT--GGGEEEEEESEEEEEEESSS.SSS...............TSTTTEEEH CS
                      xxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxx...............xxxxxxxxx RF
  Glyco_hydro_18  175 yvnvmtYDfhgswdn..vtghhaplydaslnvdeavkeylkagvpakklvlGvpfygrawalvsg.adn...............tkeegvlsy 249 
                      ++n+m+YD+hgsw++   +++h++l      ++++++ + +agv++ k++lG++ yg++++l sg   +                +e+g+l++
      EEA19455.1  850 WLNLMAYDLHGSWEQptIAEPHTNL----SDIQQSLQLVWNAGVSPGKVILGLADYGKTYTLSSGlC-TqpgcpatgpglpgpcSNEAGSLHN 937 
                      ***************9999******....8899888877799********************99950.24556666778888889******** PP

                      HHHHHHH.TEEEEEEEEETTTTEEEE.EETTEEEEE-SHHHHHHHHHHHHHTTESEEEEETGGG CS
                      xxxxxxx.xxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18  250 kelkell.kkakakrkydskakapyv.ydgeefvsyDdpksikakadyvkakglgGvmiWsldq 311 
                      +e+++ l k+   ++++d+ka   y  +d++++vsyDd+++ + k +++ +k l+G   W++d+
      EEA19455.1  938 AEIEAVLkKHTDIQPQLDKKAAIKYFsWDKTQWVSYDDEETWQLKKQFAADKCLAGTLEWAVDM 1001
                      *****9966666799*****99966559999*****************************9985 PP

>> Chitin_bind_1  Chitin recognition protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.7  17.7   2.3e-15   1.4e-11       1      38 []     615     654 ..     615     654 .. 0.97

  Alignments for each domain:
  == domain 1  score: 44.7 bits;  conditional E-value: 2.3e-15
                    B-SGGC..TT---STT-EE-TTSBEEBSHHHHSTT--BS- CS
  Chitin_bind_1   1 eCGkqa..ggatCplnvCCSqyGyCGttsdyCgagCqsnC 38 
                    +CG +a  g++ Cp+++CCS+yG+CGtt++yCg gCq+nC
     EEA19455.1 615 QCGVNAlpGQEICPQGMCCSRYGFCGTTKEYCGLGCQNNC 654
                    7****998999***************************** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1013 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       586  (0.0326845); expected 358.6 (0.02)
Passed bias filter:                      428  (0.0238719); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.80u 0.30s 00:00:01.10 Elapsed: 00:00:00.50
# Mc/sec: 6053.07
//
Query:       EEA19456.1  [L=353]
Description: plasma membrane protein Pth11-like, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (353 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       634  (0.0353617); expected 358.6 (0.02)
Passed bias filter:                      294  (0.016398); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2494.51
//
Query:       EEA19457.1  [L=490]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.2e-30  104.6  37.7      1e-28  100.3  26.5    2.0  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.089   12.9   0.2        2.8    8.1   0.1    2.3  2  RAP       RAP domain


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.3  26.5   1.1e-32     1e-28       1     333 [.      48     393 ..      48     398 .. 0.79
   2 !    9.1   4.4     6e-05      0.54      89     145 ..     397     451 ..     396     455 .. 0.90

  Alignments for each domain:
  == domain 1  score: 100.3 bits;  conditional E-value: 1.1e-32
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrr..vlllglllfalglllllfasslwlllvlrvlqGl 97 
                 l++++++s+++rs++g a    +++dl + +  ++ ++t++++ ++v+ +p+  ++ +fG++   v++++  l++lg   l+   ++  l+++r+l+G+
  EEA19457.1  48 LWFLFLVSFFDRSNIGNAKIAGMTTDLKMKGNDYNVAVTVFTVSYVVFGVPANLMVKKFGPKIlsVFMFCWGLLVLG-QGLT--KTISGLIACRFLMGM 143
                 6999**************999****************************************9966777777777777.7777..77778********** PP

       MFS_1  98 gagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg......Wravfyilaivsllafvlfllllpeepperkrkspkeee.. 188
                 ++++++p++a+li  +++++e  r ++++ +++ ++ ++  l++ ll  + g      W+++f++ ai++l + ++ ++++ ++ pe +++ + +e+  
  EEA19457.1 144 FEAGFVPGCAYLIGCYYKRNEFLRRYAVFFSANMAAGAFNGLFSTLLQKLNGrggleaWQWIFVMEAIITLCVSII-GFFIIVPFPEDAKFLTSDEKal 241
                 **********************************************9988889********************995.7888888888888888888767 PP

       MFS_1 189 ........kgtgpaplvpawkallkdpvl.....willialllfffgfsg...lltllplylqevlglsglllaglllallalvgailallagrlsdrl 271
                          g +++  ++ +k +     l     w ++i++l+ +++  +   l+++ p++  + lg+++  +a +    +++ +++l l +++lsd l
  EEA19457.1 242 lmarieedGGSVRHDEIT-LKRV-----LsmiadWKIWICVLGYMAAEETassLVAFQPTI-LKNLGWTN-TSAQWHTIPVYATAFVLTLSSAWLSDYL 332
                 777775442222222222.3333.....2333446555555555545544677*******7.*******3.333333444444445558999******* PP

       MFS_1 272 grrrrlllallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdlappee 333
                 ++r   +++++ll+++  ++ l+  + sa +l+++++++++g+++ ++++ +++  ++++  
  EEA19457.1 333 NHRYLFTVFGSLLIIIGWSIELAHKS-SAGVLYMGMFFVSCGAFINMSTIVVWLCTNVGKGV 393
                 99555555555555555555555555.777777799999***********999999887765 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 6e-05
       MFS_1  89 lvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllgglla 145
                 +++ +l+G+g +++f +g+++i+d +pk   + ++g+  a+  +G i + + +g+l+
  EEA19457.1 397 VAMGILTGFGNCGAFVSGNVFITDQSPK--YPVGFGVGLAFGVVGLIATSVYAGFLL 451
                 6899***********************8..888888888999999999999999997 PP

>> RAP  RAP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.1   0.00031       2.8      22      40 ..      32      50 ..      31      53 .. 0.90
   2 ?    2.1   0.0     0.023     2e+02      19      39 ..     289     309 ..     279     317 .. 0.77

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00031
         RAP 22 lKkriLsklGykvinIpyf 40
                l k++L+kl+++vi I +f
  EEA19457.1 32 LEKKLLRKLDFHVIPILWF 50
                6799************987 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.023
         RAP  19 ktklKkriLsklGykvinIpy 39 
                  ++++  iL++lG+   +  +
  EEA19457.1 289 LVAFQPTILKNLGWTNTSAQW 309
                 6788899*******8766555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (490 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       682  (0.0380389); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.25s 00:00:00.81 Elapsed: 00:00:00.42
# Mc/sec: 3502.35
//
Query:       EEA19458.1  [L=603]
Description: acetolactate synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-36  126.1   2.5    3.2e-36  124.5   2.4    1.9  2  TPP_enzyme_N  Thiamine pyrophosphate enzyme, N-terminal TPP b
      1e-16   61.1   0.0    2.5e-16   59.8   0.0    1.7  1  TPP_enzyme_C  Thiamine pyrophosphate enzyme, C-terminal TPP b
    4.2e-09   36.3   0.1    1.1e-08   34.8   0.1    1.8  1  TPP_enzyme_M  Thiamine pyrophosphate enzyme, central domain


Domain annotation for each model (and alignments):
>> TPP_enzyme_N  Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  124.5   2.4   5.4e-40   3.2e-36       3     170 ..      10     192 ..       9     194 .. 0.97
   2 ?   -2.9   0.0      0.74   4.4e+03     126     155 ..     568     597 ..     549     598 .. 0.81

  Alignments for each domain:
  == domain 1  score: 124.5 bits;  conditional E-value: 5.4e-40
                   HHHHHHHHHHHCT--EEEE---CCCHHHHCCHHCT.......TSEEEE-SSHHHHHHHHHHHHHHHTS-EEEEE-CHHHHHHCHHHHHHHHHHT--E CS
  TPP_enzyme_N   3 vaealvraLkalgvehvfgvpGsrilplldalseeq......girvvlarhEqgaafaAdgyaratgkpgvvlvtsgpGatnaltalaeAkvdriPl 93 
                   va+a+++aL+++gv+++f+v Gs+  ++++a  ++         r++l+ hE +a+ aAdgyar+t++p++v+v++ +G++ +  +l++A++ r P+
    EEA19458.1  10 VADAFLEALAEAGVDYLFTVLGSDHPSIIEAYVRRTklqgkeLPRMILFQHEFAAMSAADGYARITHRPACVIVHVDVGTAALGQGLHNASSGRAPV 106
                   79*****************************99999898887899**************************************************** PP

                   EEEEEE--CCCHH.........S..TC--T-CCHHHCCCSSEEEE-SSGGGHHHHHHHHHHHHHSSS--EEEEEEEHHHCC-EEEH CS
  TPP_enzyme_N  94 lvlsgdrptslrg.........qgvlqqeldqlalfrpvtkyaervtspeelpealrrAirtalsgrpgPvylelpkdvlleevde 170
                   ++++g +p++l g          ++ q+  +q++l++p+ +y+ +++s+++++ +++rA+  a++g pgPvyl+  +++l ++v++
    EEA19458.1 107 VIFAGVAPSTLHGesagsrsehVQWYQDIPNQASLVAPYSRYTAEIKSAQHVQTVVHRAVLMATTGSPGPVYLTATREMLAAPVES 192
                   ********************9989999777***************************************************99985 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.74
                   EEEE-SSGGGHHHHHHHHHHHHHSSS--EE CS
  TPP_enzyme_N 126 yaervtspeelpealrrAirtalsgrpgPv 155
                   ++ rvt++ +l+ +l +A ++ l++++ +v
    EEA19458.1 568 WTKRVTRVGDLKDVLIEAKKVVLEQKMSAV 597
                   789999999999999999999988887776 PP

>> TPP_enzyme_C  Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.8   0.0   4.2e-20   2.5e-16       4     153 .]     418     600 ..     415     600 .. 0.79

  Alignments for each domain:
  == domain 1  score: 59.8 bits;  conditional E-value: 4.2e-20
                   HHHHHHHHHHTTSSSSEEECETTTS-TTTHHHHHHHHHHH....................STTSEEEEEEEHHHHHHT..GGGHHHHHHTT-SEEEE CS
  TPP_enzyme_C   4 cltlwaarllkvkrprsyltsgglgtmGyglpaAiGakla....................kpdrevvaivGDGgflmi..lqelatavrrnlpitvv 78 
                   ++++ +++ l+++rp+s lt +g + +G++ +aAiG+kla                     ++  v  i+GDG+f ++     ++ ++r+n p++++
    EEA19458.1 418 TNQVLLSEQLRFTRPGSHLT-KGGSGLGWAGGAAIGVKLAtklydltdrpnikhkdsndsSEEPLVCMITGDGSFVFSvpTAVYWASHRHNCPFLTI 513
                   5666677778999**99999.67888*************445566667777777777653335688899******99974567899999999***** PP

                   EEE-SBCCCHHHH...HHHHTCCTTTTSBB.....BS----HHHHHHHT..TSEEE...EESSH.HHHHHHHHHHHH....CSSSEEEEEE CS
  TPP_enzyme_C  79 vlnNegygmtggq...qepfggkrksgpagk....dlkpvdfaklaeal..Gakga...rvekadveeleealkeal....ekkgpaliev 153
                   vlnN+g+ +t++     +p+g  +++++++     +l+ +++ ++a+a+  G   +   rv++    +l+++l ea     e+k +a+++v
    EEA19458.1 514 VLNNGGWRATRQCivdVHPQGVASTVTNQDLgislELDGPNYGEVAKAAanGH--LwtkRVTRV--GDLKDVLIEAKkvvlEQKMSAVVDV 600
                   **************888888877777766559*9879999********84333..244576666..*******999878889999999997 PP

>> TPP_enzyme_M  Thiamine pyrophosphate enzyme, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.8   0.1   1.9e-12   1.1e-08       2     120 ..     214     325 ..     213     345 .. 0.83

  Alignments for each domain:
  == domain 1  score: 34.8 bits;  conditional E-value: 1.9e-12
                   HHHHHHHHH-SSEEEEE-CHHCHTTGHHHHHHHHHHH.T-EEEEEGGGTTSS-TTSTTEEEESGGGSCHHHHHHHHH-SEEEEES-SSSTCCCTTTT CS
  TPP_enzyme_M   2 ekaaellkaakrpvilvGggvarsgaseelrelaekl.giPvvttlmgkgvipedhplylgmlglhgskaanealeeaDlvlalGarfddirttgse 97 
                   e +a++l +a+ p+++ G   ++++a + l++l++ + gi v+++     ++p dhp +     +++ + a ++l++aD+vl+l a+  +i t    
    EEA19458.1 214 ELVADALIKAEAPLVITGYLGRNHQAVKNLVALVDIVkGIRVFDSEIREVCFPADHPAW-----VTRGTGAAKVLQSADVVLVLDADVPWIPT---- 301
                   6689*******************************98569*****************99.....456788999*****************754.... PP

                   T.TTTTT-EEEEEESSCCCCTTCC CS
  TPP_enzyme_M  98 p.efapeakiihididpaeigkny 120
                   + + +p a+i hid dp + + n 
    EEA19458.1 302 RvRPSPSAQIFHIDLDPRKEKMNL 325
                   324456679********8766665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (603 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       412  (0.0229795); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 4168.64
//
Query:       EEA19459.1  [L=283]
Description: hypothetical protein PMAA_002520 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (283 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       423  (0.0235931); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1997.18
//
Query:       EEA19460.1  [L=363]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (363 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       521  (0.0290591); expected 358.6 (0.02)
Passed bias filter:                      309  (0.0172346); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 2567.43
//
Query:       EEA19461.1  [L=712]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.3e-36  125.5  27.8      1e-28  100.3   9.6    2.6  3  MFS_1          Major Facilitator Superfamily
    3.9e-15   55.7   3.7    3.9e-15   55.7   3.7    2.6  3  Sugar_tr       Sugar (and other) transporter
     0.0017   16.9   4.2     0.0029   16.1   4.2    1.2  1  TRI12          Fungal trichothecene efflux pump (TRI12)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.3   9.6   1.7e-32     1e-28      12     186 ..     117     295 ..     104     349 .. 0.84
   2 !   34.2   5.9   2.1e-12   1.3e-08     188     345 ..     473     650 ..     436     658 .. 0.77
   3 ?   -1.5   0.2      0.16   9.4e+02     140     171 ..     658     693 ..     654     707 .. 0.48

  Alignments for each domain:
  == domain 1  score: 100.3 bits;  conditional E-value: 1.7e-32
       MFS_1  12 rsilgpalpl.alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgagalfpagaal 109
                 ++   +a+    +a+d+g+s +++   ++ly+lg +++s+++++ +  +G r+v+llg++lf+l++++++++++++ l+v+r+++G++ + +  +  a 
  EEA19461.1 117 MT-PVLAAGFnDVAKDYGVSTQQVAYTTGLYMLGLGFGSVIMAPTAILWGKRPVYLLGATLFILSAVWCALSTNYPSLVVARIFMGIAVSPVECLPSAT 214
                 33.33333333889***************************************************77777678888*********************** PP

       MFS_1 110 iadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllll.....peepperkrkspke 186
                 ia++f   er+  ig++++    G  l pl++++++ +lgWr+vf+++aiv   ++++ l+++     +++ p+rk+k+ ++
  EEA19461.1 215 IAEIFFLHERAYRIGIYTLLLLGGKNLVPLASAAIIGALGWRWVFWVVAIVVGGSLIF-LFFFvpetfWDRTPRRKPKARRP 295
                 *******************************************************885.34444666655555555544444 PP

  == domain 2  score: 34.2 bits;  conditional E-value: 2.1e-12
       MFS_1 188 e......kgtgpaplvpawkallkdpvlwillialllfffgfsglltllply.lqevlglsglllaglllallalvgailallagrlsdr......... 270
                 +       ++ +a+++p + ++  + vlw++l+ +l++++ + +  +   +y  +e++++s +l +gl++  ++++g+ +  +agr+sd          
  EEA19461.1 473 WngrlshDKWYRAAIRP-FILFAYPAVLWSALVYSLSIGWLIVLSESVAVIYeNHETYNFS-ALGTGLVYISPFVGGVLGTAVAGRVSDIivrymtrrn 569
                 14445555678888888.8889999999*55555555545666655555555458999999.899999999999999999**********999998888 PP

       MFS_1 271 ...lgrrrrlllallllllaalglallavtssavllll.vlvliGf.glgfv..fpsllalasdlappeeagtasglfntag 345
                    + +++rl++a++++l +a+gl+ ++++ +   +++ + +++G+  +g+   +++++++++d++  ++ag a+   n+  
  EEA19461.1 570 ggiYEPEFRLVMAIPVALSTAAGLMGFGWSVEERDAWIvPTIFFGIiSFGCSlgSTTSITFCVDSYR-QYAGEALVTLNFSK 650
                 888888************************5555555546666666666666669999999999995.99998888777765 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 0.16
       MFS_1 140 lggllasslg...Wravfyilaivsllafv.lflll 171
                 ++ +++++l     r vf++++++ + +++  + ++
  EEA19461.1 658 FSLFIVDWLKsdgTRTVFLAIGGIQIACLLtSIPMY 693
                 444444444344455555555555555544323333 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.7   3.7   6.6e-19   3.9e-15      42     209 ..     133     294 ..      80     303 .. 0.87
   2 ?    0.6   0.2     0.033     2e+02      34      73 ..     522     561 ..     493     572 .. 0.79
   3 ?   -2.0   0.5      0.21   1.3e+03      49      66 ..     610     627 ..     580     695 .. 0.69

  Alignments for each domain:
  == domain 1  score: 55.7 bits;  conditional E-value: 6.6e-19
                 HH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHH CS
    Sugar_tr  42 eessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalv 140
                   s+ ++  +++++++G  +Gs+++ + +  +G+++++l +a+lf+ +av +a+++   ++  l+v+R+++Gi+v  + +l + +i+Ei   + R + +
  EEA19461.1 133 GVSTQQVAYTTGLYMLGLGFGSVIMAPTAILWGKRPVYLLGATLFILSAVWCALST---NYPSLVVARIFMGIAVSPVECLPSATIAEIFFLHERAYRI 228
                 237789999***********************************************...9*************************************** PP

                 HHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCC.HHHHHHHHHHGGGS---HHHHHHTT-HHHHHH CS
    Sugar_tr 141 slyqlaitfGilvaaifglglnktsnadgwrillglq.lvpallllilllflPESPrylvekgkeeeake 209
                 ++y l +  G  +     +++   ++  gwr+ +++  +v    l++l++f+PE+ ++  + +++ +a++
  EEA19461.1 229 GIYTLLLLGGKNLVPLASAAII--GA-LGWRWVFWVVaIVVGGSLIFLFFFVPET-FWDRTPRRKPKARR 294
                 **********988766655554..34.77*****986156788999999******.88887777777765 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.033
                 T--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHT CS
    Sugar_tr  34 lsksksskeessvlsglivsiflvGaiiGslfagllgdrf 73 
                  ++++++++ s++ +gl+  + +vG+++G  +ag ++d++
  EEA19461.1 522 IYENHETYNFSALGTGLVYISPFVGGVLGTAVAGRVSDII 561
                 344555555588889*******************999976 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 0.21
                 HHHHHTHHHHHHHHHHHH CS
    Sugar_tr  49 glivsiflvGaiiGslfa 66 
                 +++++i ++G+ +Gs ++
  EEA19461.1 610 TIFFGIISFGCSLGSTTS 627
                 566666666666666543 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   4.2   4.8e-07    0.0029      65     222 ..     123     281 ..     117     294 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 4.8e-07
       TRI12  65 salpnilqdvgqsensslfst.lwttgqavsilvmgrltdrfgrrpfvilthilglvgaivgctatkfntllaamtllgvaagpagaspl.fvgelmsn 161
                 + + ++ +d g s ++  ++t l+ +g     ++m   +  +g+rp+ +l   l ++ a+  + +t++ +l+ a  ++g+a  p  + p   + e++  
  EEA19461.1 123 AGFNDVAKDYGVSTQQVAYTTgLYMLGLGFGSVIMAPTAILWGKRPVYLLGATLFILSAVWCALSTNYPSLVVARIFMGIAVSPVECLPSaTIAEIFFL 221
                 556788999****999988876999***********************************9999*********************99985279999888 PP

       TRI12 162 ktkflgllivsipvvvtsglspylgqrlaiqgswrwifyiyiitsaiavllivvwyy.ppsf 222
                 + +   + i ++  +  + l p     +     wrw+f++  i+      li ++++ p +f
  EEA19461.1 222 HERAYRIGIYTLLLLGGKNLVPLASAAIIGALGWRWVFWVVAIVVG--GSLIFLFFFvPETF 281
                 877777777777888888899998887777778*****99877644..44555555414455 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (712 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       564  (0.0314574); expected 358.6 (0.02)
Passed bias filter:                      315  (0.0175693); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.64u 0.26s 00:00:00.90 Elapsed: 00:00:00.41
# Mc/sec: 5209.36
//
Query:       EEA19462.1  [L=523]
Description: UPF0016 domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.6e-41  138.1  26.7    1.5e-20   73.3  11.7    2.4  2  UPF0016   Uncharacterized protein family UPF0016
  ------ inclusion threshold ------
      0.016   13.6   1.3      0.028   12.7   1.3    1.3  1  DUF2070   Predicted membrane protein (DUF2070)
        0.1   11.4   0.1       0.17   10.7   0.1    1.2  1  YIEGIA    YIEGIA protein


Domain annotation for each model (and alignments):
>> UPF0016  Uncharacterized protein family UPF0016
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.3  11.7   2.5e-24   1.5e-20       2      75 .]     260     333 ..     259     333 .. 0.96
   2 !   70.6   7.0   1.7e-23     1e-19       1      75 []     440     514 ..     440     514 .. 0.99

  Alignments for each domain:
  == domain 1  score: 73.3 bits;  conditional E-value: 2.5e-24
     UPF0016   2 aaflliflaElGDkTqlaaalLaarykplpVflGavlAlalmtvlsvllGsslakrlperlielvaavlFllfG 75 
                  +f++i+++E+GDkT+l+aal+a+r+  l Vf++a+ Al+ mtvls++lG+++ +++p  +++++aa+lFl+f+
  EEA19462.1 260 LSFTMILVSEIGDKTFLIAALMAMRHPRLVVFTAAFSALITMTVLSAVLGHAVPTLIPAAYTQFAAAILFLVFA 333
                 59************************6666*******************************************7 PP

  == domain 2  score: 70.6 bits;  conditional E-value: 1.7e-23
     UPF0016   1 laaflliflaElGDkTqlaaalLaarykplpVflGavlAlalmtvlsvllGsslakrlperlielvaavlFllfG 75 
                 +++f+++fl E+GD++q+a++++aa +++++V++Gavl++ ++t+++v+ G+++a+r++ r ++l +a +Fl+fG
  EEA19462.1 440 VQTFVMTFLGEWGDRSQIATIAMAAGQDYWWVTIGAVLGHSICTAVAVIGGRAIAGRVSLRAVTLGGAGAFLVFG 514
                 589***********************************************************************9 PP

>> DUF2070  Predicted membrane protein (DUF2070)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   1.3   4.7e-06     0.028      66     148 ..     252     333 ..     240     353 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 4.7e-06
     DUF2070  66 ltykrslflalltelivviisllaillsallqalvllalvlslalvfalrllvlvavsdesllkavlpaliqpllailllvly 148
                 +   +slfl++++ l++ i +   ++++++     +  +v++ a+++ +++ vl av ++ +++ +  a +q ++ail+lv+ 
  EEA19462.1 252 FSPIHSLFLSFTMILVSEIGDKTFLIAALMA-MRHPRLVVFTAAFSALITMTVLSAVLGHAVPTLIPAAYTQFAAAILFLVFA 333
                 4445668888888888888666666555433.445667778889999999999999999999988877777777777777765 PP

>> YIEGIA  YIEGIA protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.1   2.8e-05      0.17      35      76 ..     299     343 ..     291     366 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 2.8e-05
      YIEGIA  35 lalgfiaaalGavaipallekeft....avTFLalaaqqFrdvrnm 76 
                 +++++++a+lG  a+p+l+   +t    a+ FL  aa+ F++ r m
  EEA19462.1 299 ITMTVLSAVLGH-AVPTLIPAAYTqfaaAILFLVFAAKMFKEGRGM 343
                 7899999***96.67777776664444499***********98877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (523 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       956  (0.0533214); expected 358.6 (0.02)
Passed bias filter:                      485  (0.0270511); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.44
# Mc/sec: 3583.38
//
Query:       EEA19463.1  [L=836]
Description: MYB DNA-binding domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.9e-07   30.1   0.3    7.4e-07   29.3   0.3    1.5  1  Myb_DNA-binding  Myb-like DNA-binding domain
     0.0029   17.8   0.2     0.0061   16.8   0.2    1.5  1  Myb_DNA-bind_6   Myb-like DNA-binding domain
  ------ inclusion threshold ------
       0.27   11.2   0.0       0.71    9.9   0.0    1.6  2  DUF3963          Protein of unknown function (DUF3963)


Domain annotation for each model (and alignments):
>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.3   0.3   1.2e-10   7.4e-07       1      44 [.     734     784 ..     734     786 .. 0.74

  Alignments for each domain:
  == domain 1  score: 29.3 bits;  conditional E-value: 1.2e-10
                      CSSSBHHHHHHHHHHHHHHTTCHHHHHH..HHTS.....S-HHHHHHHHHH CS
  Myb_DNA-binding   1 rgkWteeEdelLleavkkhGnrWkkIae..rlgg.....Rtekqcrsrwrn 44 
                      r +Wt eEde+++++v+++G +W+kI +  +l g     R   + ++r rn
       EEA19463.1 734 RRPWTREEDEQFIRLVEEYGISWSKIKSqdELSGrvlhlRKQVDLKDRARN 784
                      689***********************5546444333333666666666666 PP

>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.2     1e-06    0.0061       1      26 [.     737     762 ..     737     788 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 1e-06
  Myb_DNA-bind_6   1 WteeEdeiLlklvekygndWknIaea 26 
                     Wt eEde  ++lve+yg  W++I ++
      EEA19463.1 737 WTREEDEQFIRLVEEYGISWSKIKSQ 762
                     ***********************543 PP

>> DUF3963  Protein of unknown function (DUF3963)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0   0.00012      0.71      10      27 ..     410     427 ..     406     429 .. 0.94
   2 ?   -3.2   0.0       1.5     9e+03      15      22 ..     450     457 ..     445     459 .. 0.69

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00012
     DUF3963  10 EkYFgDiqKWiRNitfCF 27 
                 E+Y +D+   iR it CF
  EEA19463.1 410 EQYVQDVTDRIREITACF 427
                 99**************** PP

  == domain 2  score: -3.2 bits;  conditional E-value: 1.5
     DUF3963  15 DiqKWiRN 22 
                  + KW+R 
  EEA19463.1 450 TVAKWLRS 457
                 56799986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (836 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       974  (0.0543254); expected 358.6 (0.02)
Passed bias filter:                      506  (0.0282224); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.73u 0.30s 00:00:01.03 Elapsed: 00:00:00.47
# Mc/sec: 5359.04
//
Query:       EEA19464.1  [L=214]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.7e-15   55.6   0.0      1e-14   55.3   0.0    1.1  1  Lipase_GDSL_2  GDSL-like Lipase/Acylhydrolase family
    8.8e-12   45.4   0.0    1.5e-11   44.6   0.0    1.4  1  Lipase_GDSL    GDSL-like Lipase/Acylhydrolase


Domain annotation for each model (and alignments):
>> Lipase_GDSL_2  GDSL-like Lipase/Acylhydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.3   0.0   1.2e-18     1e-14       1     179 []       7     195 ..       7     195 .. 0.66

  Alignments for each domain:
  == domain 1  score: 55.3 bits;  conditional E-value: 1.2e-18
                    EEESHHHHTCTTB..CCHCHHCCCCCCCHHHTT.............-EEEEE.EEHCCH-H..HHHHHHHHCTGGG-T................SE CS
  Lipase_GDSL_2   1 alGDSiTaGygad..gggrsypaylarllaarl.............gldvvnnlgvsGattallrllerlrdllrlkp................dl 65 
                    ++G+S+TaG+ +       +++ y a  l+++l             g   +++ g +G+             l    p                d+
     EEA19464.1   7 CFGNSLTAGFRSYgiK---PDHPY-ALTLKEQLlaagldasilggdGKVDIDVEGQPGD-------------LVNCPPghfvermkwmldaktfDW 85 
                    9**********96663...44444.4444444433312444443332222222555555.............333333444444444666666899 PP

                    EEEE--CCCCCTT--HHHHHHH..HHHHHHHHCCC...GEEECEEEEE-TTT-TTSTCCHHHHHHHHHHHHHHHHHHCT-EEE-H...HHHHHHCC CS
  Lipase_GDSL_2  66 vtiliGtNDlgrgvpaaaaaandnleelidalraaapgarilvlgplpptpeaaadarelnaviaaynealrevaaeegvpfvDl...hdaladsg 158
                    +++l GtNDlg+g  ++++    +l+  ++ + +a p+++il + ++p + ++ a+     ++++a+n+++ e  +e   + +Dl    +    ++
     EEA19464.1  86 IIVLGGTNDLGYGSFTPDQIYT-GLKITWTLALSAPPNTKIL-ALTVPECASTNAKL---TRNRNALNKLILEHEEE-RFYAFDLksaIPYHDMDE 175
                    ***********99999887766.499999999**********.55555555555554...559***********999.888899966633334445 PP

                    CCCGGBBTTS.SSB-HHHHHH CS
  Lipase_GDSL_2 159 erladlladdglHPnaaGyrl 179
                    +r ++ +ad+ lH++++Gy+l
     EEA19464.1 176 KRREEIWADG-LHFTEKGYDL 195
                    6677889998.********85 PP

>> Lipase_GDSL  GDSL-like Lipase/Acylhydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.6   0.0   1.7e-15   1.5e-11       1     199 [.       5     199 ..       5     200 .. 0.66

  Alignments for each domain:
  == domain 1  score: 44.6 bits;  conditional E-value: 1.7e-15
                  EEEEESHHHHTT...................THHHHHHHCCCCEECCCTTC.GCEEEEEEECTTHHHHHHHCCH........ECTTTECHHHHHCTTS CS
                  xxxxxxxxxxxx...................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxx RF
  Lipase_GDSL   1 ivafGDSltdGd...................gaatlntiqlktpknlnefdlaldrianignkgasdnelqqll........nkyplkseqlkalhpd 71 
                  i++fG Slt+G+                                        +ld   ++g ++ +   + q          + ++++++ l+a+ +d
   EEA19464.1   5 ILCFGNSLTAGFrsygikpdhpyaltlkeqlL---------AA---------GLDASILGGDGKVDIDVEGQPGdlvncppgHFVERMKWMLDAKTFD 84 
                  7899*****99866555554442222222221.........11.........3333333333333333333333446666655599************ PP

                  EEEEE--CTCC-EECSSCTTTCEEHHHHHHHHHHHHHHHHHHHHTTEEEEEEE-SSTCHCTCCCCHCCHHHHHHHHHHHHHHHHHHHH........HC CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xx RF
  Lipase_GDSL  72 lviislGtNDsnlgkkstdaakkeaeeyiknlreaikelkeegapkaivvlvsppglgpqeekdakklgekgnefvgeynqrlndlae........kd 161
                  ++i+  GtND+            +++++++ l+ +   l  + +p+++++ +++p++++  +++ +  ++ +n+++ e+        e        k+
   EEA19464.1  85 WIIVLGGTNDL-------GYGSFTPDQIYTGLKITWT-LALSAPPNTKILALTVPECAS-TNAKLTRNRNALNKLILEHE-------EerfyafdlKS 166
                  ***********.......5567788889999988866.777788***************.22222222333333333333.......24555677899 PP

                  TEEEECHHHHHHHTHCCGCHCHTSSSB-HHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Lipase_GDSL 162 gfavvDlydelqglsgieqlkaDglHpsekgyeklael 199
                   ++++D+ ++  +      ++aDglH++ekgy +++e 
   EEA19464.1 167 AIPYHDMDEKRREE-----IWADGLHFTEKGYDLMGEV 199
                  99999998877777.....667*************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (214 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       263  (0.014669); expected 358.6 (0.02)
Passed bias filter:                      253  (0.0141112); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.43u 0.28s 00:00:00.71 Elapsed: 00:00:00.44
# Mc/sec: 1468.35
//
Query:       EEA19465.1  [L=163]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-43  148.4   1.9    3.8e-43  147.4   1.9    1.4  1  DUF1993   Domain of unknown function (DUF1993)
  ------ inclusion threshold ------
      0.015   14.4   0.2      0.018   14.2   0.2    1.1  1  DUF3422   Protein of unknown function (DUF3422)
      0.035   12.7   0.1      0.042   12.5   0.1    1.1  1  DHR-2     Dock homology region 2
      0.076   13.5   0.0       0.09   13.3   0.0    1.2  1  DinB_2    DinB superfamily
      0.086   13.0   0.1       0.11   12.6   0.1    1.2  1  DUF848    Gammaherpesvirus protein of unknown function (DUF84


Domain annotation for each model (and alignments):
>> DUF1993  Domain of unknown function (DUF1993)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  147.4   1.9   1.1e-46   3.8e-43       1     161 []       4     156 ..       4     156 .. 0.95

  Alignments for each domain:
  == domain 1  score: 147.4 bits;  conditional E-value: 1.1e-46
                 HHHHCHHHHHHHHHHHHHHHHHHHCCHHHH.C..HHHHHT--SSTTS--HHHHHHHHHHHHHHHHCHHCT-GS----S.-SSHHHHHHHHHHHHHHHHC CS
     DUF1993   1 lydasvpvfikglknlsalLkkaeahaaak.kidpeellearLapDMlpLsfQvqiatdtakkavarlagkeppsledeektfadlrariaktialLes 98 
                 ly+++vp+fi++l+nls+lL+k++++a++k +++++++l+ rL++DM +L+fQvq +t++ak++ +rl  +e+ ++ed e+ +++l++ri++ti++L++
  EEA19465.1   4 LYKQTVPIFIHYLNNLSNLLTKGAEFAEQKeGMTEASMLSFRLIEDMRELTFQVQGCTSIAKATPQRLDPHEVLTVEDVETALEELQERIKRTIEILQT 102
                 8****************************97888888************************************************************** PP

                 S-GGGHCCCCCEEEE.C.CCCCEEEE.HHHHHHHTHHHHHHHHHHHHHHHHHHCT----HHHHH CS
     DUF1993  99 vdpekldakeekevelklggkeleft.geeyllefalPnfyFHlttaYaILRkkGVelGkaDyl 161
                 ++pe++da  +          +++f  g+ y+ ++a+P f FHl taY+I+R+ GV+lG  Dyl
  EEA19465.1 103 AKPEAMDAMMG----------NFQFAtGQIYVSQYAIPSFNFHLATAYCIMRHLGVPLGAVDYL 156
                 *****998654..........444433************************************7 PP

>> DUF3422  Protein of unknown function (DUF3422)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.2   5.1e-06     0.018     278     330 ..      47     102 ..      13     104 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 5.1e-06
     DUF3422 278 laeLree..rieglqtlseFlerRlaPA.mrtceaveerledLserlarasaLLrt 330
                 ++++re   +++g+ ++++ + +Rl+P  + t+e ve+ le+L+er++r+ ++L+t
  EEA19465.1  47 IEDMRELtfQVQGCTSIAKATPQRLDPHeVLTVEDVETALEELQERIKRTIEILQT 102
                 455565511466***************6599************************9 PP

>> DHR-2  Dock homology region 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.1   1.2e-05     0.042     101     208 ..       4     103 ..       1     114 [. 0.77

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.2e-05
       DHR-2 101 syksspdlritwLeslaekhaenenfsEaaqclihaaaLiaeylkll.kkipkklgasaFekispnvlkeesesasalkedsgvcdseefteeglvell 198
                 +yk++  + i +L++l++ + +  +f+E    ++ a+ L  + ++ + +   +  g+++++k++p+ l ++ +++ ++++   v++      e l+e +
  EEA19465.1   4 LYKQTVPIFIHYLNNLSNLLTKGAEFAEQKEGMTEASMLSFRLIEDMrELTFQVQGCTSIAKATPQRL-DP-HEVLTVED---VET----ALEELQERI 93 
                 588888899*******************9988887777777665555234477778*********998.66.67777877...222....466677777 PP

       DHR-2 199 ekaiellkkg 208
                 +++ie+l+ +
  EEA19465.1  94 KRTIEILQTA 103
                 7777777766 PP

>> DinB_2  DinB superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   2.5e-05      0.09      57     101 ..      68     115 ..      14     133 .. 0.74

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 2.5e-05
      DinB_2  57 rpgldpltp...psaaealaylaevrarllallealtdadldrpltap 101
                 + +ldp++     +++ al++l+e  +r++++l++++++++d+ + + 
  EEA19465.1  68 PQRLDPHEVltvEDVETALEELQERIKRTIEILQTAKPEAMDAMMGNF 115
                 233444444333799999999999999999999999999998877665 PP

>> DUF848  Gammaherpesvirus protein of unknown function (DUF848)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.1     3e-05      0.11      80     118 ..      69     107 ..      24     115 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 3e-05
      DUF848  80 kklnrkkvarveeLtdkvlelkeevsleldsleeaqeey 118
                 ++l++++v +ve+   + +el+e ++  ++ l+ a++e 
  EEA19465.1  69 QRLDPHEVLTVEDVETALEELQERIKRTIEILQTAKPEA 107
                 579******************************998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (163 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1200  (0.0669307); expected 358.6 (0.02)
Passed bias filter:                      957  (0.0533772); expected 358.6 (0.02)
Passed Vit filter:                        87  (0.00485247); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.54u 0.31s 00:00:00.85 Elapsed: 00:00:00.49
# Mc/sec: 996.90
//
Query:       EEA19466.1  [L=258]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.8e-05   23.8   0.0    5.8e-05   23.8   0.0    2.5  2  GPI-anchored  Ser-Thr-rich glycosyl-phosphatidyl-inositol-anc


Domain annotation for each model (and alignments):
>> GPI-anchored  Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.0   3.2e-09   5.8e-05       2      93 .]      26     120 ..      25     120 .. 0.86
   2 ?   -3.0   3.9      0.71   1.3e+04      16      22 ..     158     164 ..     125     236 .. 0.64

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 3.2e-09
  GPI-anchored   2 sPssgevvtagkpvtitWkdsgtdpgtvtlvLcagssnnlksvktiasgiknsd.gsytwtvpa.slesggaYflqivsesne.giynySdrFti 93 
                   +P+ g++v+ag  +++ W   ++dp+  +++L + + ++l   + i+s i++++  ++t  +p+ +  ++g+Y + +   +++ g++  S  Fti
    EEA19466.1  26 KPADGDTVDAGNGFDVVWLYTSADPSDWEILLANPAPTKLLATDVIVSPISGTAtSTATHHIPSvTGIPDGNYRVIMDPRNKGiGAFPGSGEFTI 120
                   799************************************************77635666677775667888999999988887788888888886 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.71
  GPI-anchored  16 titWkds 22 
                    +t  + 
    EEA19466.1 158 SVTSIPT 164
                   2222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (258 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       729  (0.0406604); expected 358.6 (0.02)
Passed bias filter:                      300  (0.0167327); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 1671.76
//
Query:       EEA19467.1  [L=258]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.8e-05   23.8   0.0    5.8e-05   23.8   0.0    2.5  2  GPI-anchored  Ser-Thr-rich glycosyl-phosphatidyl-inositol-anc


Domain annotation for each model (and alignments):
>> GPI-anchored  Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.0   3.2e-09   5.8e-05       2      93 .]      26     120 ..      25     120 .. 0.86
   2 ?   -3.0   3.9      0.71   1.3e+04      16      22 ..     158     164 ..     125     236 .. 0.64

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 3.2e-09
  GPI-anchored   2 sPssgevvtagkpvtitWkdsgtdpgtvtlvLcagssnnlksvktiasgiknsd.gsytwtvpa.slesggaYflqivsesne.giynySdrFti 93 
                   +P+ g++v+ag  +++ W   ++dp+  +++L + + ++l   + i+s i++++  ++t  +p+ +  ++g+Y + +   +++ g++  S  Fti
    EEA19467.1  26 KPADGDTVDAGNGFDVVWLYTSADPSDWEILLANPAPTKLLATDVIVSPISGTAtSTATHHIPSvTGIPDGNYRVIMDPRNKGiGAFPGSGEFTI 120
                   799************************************************77635666677775667888999999988887788888888886 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.71
  GPI-anchored  16 titWkds 22 
                    +t  + 
    EEA19467.1 158 SVTSIPT 164
                   2222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (258 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       729  (0.0406604); expected 358.6 (0.02)
Passed bias filter:                      300  (0.0167327); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.24s 00:00:00.71 Elapsed: 00:00:00.39
# Mc/sec: 1994.37
//
Query:       EEA19468.1  [L=557]
Description: vacuolar carboxypeptidase Cps1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.7e-35  122.0   0.0      4e-35  121.4   0.0    1.3  1  Peptidase_M20  Peptidase family M20/M25/M40
    1.3e-09   37.9   0.1    3.1e-09   36.7   0.1    1.7  1  M20_dimer      Peptidase dimerisation domain


Domain annotation for each model (and alignments):
>> Peptidase_M20  Peptidase family M20/M25/M40
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.4   0.0   4.5e-39     4e-35       1     206 [.     150     550 ..     150     551 .. 0.91

  Alignments for each domain:
  == domain 1  score: 121.4 bits;  conditional E-value: 4.5e-39
                    EEEEES-BSSTTCGGGSSS.TTSEEETTTEEESTTTTTTHHHHHHHHHHHHHHHHHTTT-SSEEEEEEESTTSSTT.THHHHHHHHHHTTTCESEE CS
                    xxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxx RF
  Peptidase_M20   1 llgsHlDvVpeeetdgwtt.pfslteedGklyGrGaddmkggvlaalealralkdegikpkgtivllfqpdEEggr.gGakallegleerekvdav 94 
                    l+++H+DvVp ++ ++wt+ pfs++ +   l+GrG++d+k++++++l a++ l ++g +p +t+vl f +dEE+ + +Ga+ l e+le+r++ d  
     EEA19468.1 150 LFMAHQDVVPIDDPNDWTYpPFSGHYDGQWLWGRGSSDCKNSLIGVLSAVEDLLKQGWTPTRTLVLSFGYDEESKGwKGAGCLSEHLEKRYGKDS- 244
                    79********666669*********99669*******************************************8778********9998899999. PP

                    EEEEEESSSBTCHSTETEEEE........................................................................... CS
                    xxxxxxxxxxxxxxxxxxxxx........................................................................... RF
  Peptidase_M20  95 felhieepgileagklaigvv........................................................................... 115
                    fe++i e+g+   ++++ +++                                                                           
     EEA19468.1 245 FEFIIDEGGVGI-NTIGDKIYamagvgekgavdihislsidgghssippphtgigiiseiiyhlereqlftprldlshpsrqgltcqakhsvdfve 339
                    99*********9.99899999*************************************************************************** PP

                    ................................................................................................ CS
                    ................................................................................................ RF
  Peptidase_M20 116 ................................................................................................ 115
                                                                                                                    
     EEA19468.1 340 pwlwsalessdytglaealaasrgdrvrflyqtsqaadlihggvkinalpekisatvnyrvaihentdmvrarainiitpiakahnltfsafgsgd 435
                    ************************************************************************************************ PP

                    ......EEEEEEE.EEESHEEEC....CHHHHHHHHHHHHHHH...TSC.EEEE.EES...SSBHTHHHHTTT.EEEEEEESS..G..GCTTSTTT CS
                    ......xxxxxxx.xxxxxxxxx....xxxxxxxxxxxxxxxx...xxx.xxxx.xxx...xxxxxxxxxxxx.xxxxxxxxx..x..xxxxxxxx RF
  Peptidase_M20 116 ......kvevell.eggapvtln....dsplvkalaeaaeelf...gek.veli.vsg...pggtdarffagi.ptvmifgpg..s..glaHspnE 187
                          + +++++    +p++++    +++++  ++ +++++f     +  +++ v g   +g+td+rf++++  +++ f p   +  +++H+++E
     EEA19468.1 436 kpqannHLDISDYdLPLEPAPISptspSDAIWTRMSGVTRQFFeslPASnNRTVlVVGdvmTGNTDTRFYWNLtRNIWRFSPIrpDgaKNIHTVDE 531
                    *****94666655544444444444579*************997552334555557778999********999657755665533259******** PP

                    EEEHHHHHHHHHHHHHHHH CS
                    xxxxxxxxxxxxxxxxxxx RF
  Peptidase_M20 188 yvdledlekgikvlarlle 206
                     +d++ + +g++++++l++
     EEA19468.1 532 GIDMAVHLEGLAFYYELIR 550
                    *****************97 PP

>> M20_dimer  Peptidase dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.7   0.1   3.5e-13   3.1e-09       1     107 [.     269     423 ..     269     425 .. 0.95

  Alignments for each domain:
  == domain 1  score: 36.7 bits;  conditional E-value: 3.5e-13
                 SEB-EEEEEEEEEE-B-EEGG.-TTTTB-HHHHHHHHHHCSCTTEEC.................................................... CS
   M20_dimer   1 ighkGlaggkitvkgkagHsg.apgagaNAieklarllaeledeegdia.................................................e 49 
                 +g+kG+++ +i+  + +gHs+ +p +    i + ++++ +le e+  +                                                   
  EEA19468.1 269 VGEKGAVDIHISLSIDGGHSSiPPPHT--GIGIISEIIYHLEREQLFTPrldlshpsrqgltcqakhsvdfvepwlwsalessdytglaealaasrgdR 365
                 699*******************98888..8*************9666559***********************************************99 PP

                 ..TCCTCCCCCEECCE-CCCCEESSEEEEEEEEEHHHHHHHHHHHHHHHHHHTSCCST CS
   M20_dimer  50 erslprttlnvtgiegGsaknvipdeaeakidiRllpgedpeevleeieeilekeape 107
                  r+l +t+ +   i+gG ++n++p++ +a+++ R+  +e+ + v+++  +i+   a++
  EEA19468.1 366 VRFLYQTSQAADLIHGGVKINALPEKISATVNYRVAIHENTDMVRARAINIITPIAKA 423
                 9999*********************************************999988876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (557 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       256  (0.0142785); expected 358.6 (0.02)
Passed bias filter:                      253  (0.0141112); expected 358.6 (0.02)
Passed Vit filter:                         9  (0.00050198); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.24s 00:00:00.78 Elapsed: 00:00:00.40
# Mc/sec: 4134.73
//
Query:       EEA19469.1  [L=488]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.2e-27   94.1   0.2    4.3e-26   91.5   0.2    1.9  1  AATase        Alcohol acetyltransferase
    0.00011   21.1   0.2     0.0071   15.1   0.0    2.2  2  Condensation  Condensation domain


Domain annotation for each model (and alignments):
>> AATase  Alcohol acetyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.5   0.2   4.8e-30   4.3e-26       8     483 ..      23     465 ..      22     481 .. 0.76

  Alignments for each domain:
  == domain 1  score: 91.5 bits;  conditional E-value: 4.8e-30
      AATase   8 yfvvrnrqklysnfsvyaelnke..vd....keqLalalrslilknpiLaaniipkkfpeheayyssdeyyskPfpkeDyvkviekiklddvvlneqpe 100
                 y+++++++ +y+n+ v++ + +   +d    ++ ++ al+++i  +p L  ni              d+  s+P     y   +++i+l++ v      
  EEA19469.1  23 YLIAKHSLGFYNNVAVSVFYTNRspLDvqhlQSFIYRALKEVIADHPALGVNIK-------------DDDKSRP-----YYVQLPTIDLSKTV------ 97 
                 666777777777777777664431122111133457788888888888888887.............4445566.....55556688888888...... PP

      AATase 101 yselle..kileeykdddekvdeelnellselvipvgdpkkPlwrlivlpsaddkkkwkkfv..fitdHllfDGisgvnffkdlleelekikqdnalkk 195
                    ++    i +    ++ k  + l+e  ++ +++ +  + Plwrl+++ +  +     +fv  f++ H ++DG+sg  f++ l  +l++i      ++
  EEA19469.1  98 --TFIPsvAIPNPLDPEGVKNLDLLLEEQHNRNFKDQASQDPLWRLLIVHEPVES---SRFVacFVYHHGICDGTSGLVFHQHLHRKLNQIPISDTDQE 191
                 ..44441146677777888888888888889999999999*********997444...566666***************************98888799 PP

      AATase 196 devildyekdveelekLPkpieekvdyrpsllalpklllvsfiasklnfkkseekplt.kehsavqksnkshqiilkispeevkkirakikknvhgkat 293
                  + i+  ++       LP  +e+    +p l    ++ll   ++++l  +ks+++  t +++   + +  ++ +++++s e   ++ a ++ +   +++
  EEA19469.1 192 ADAIVATSSKAF----LP-ALEDL---HP-LPLSTRFLLKAILKEHLVSEKSKRHIWTaAPITSDPSKRRCRYRSVRFSQETTSQLLAACRAQ---STS 278
                 999999888777....99.45543...33.3333466666666667666665333333123334445788999********************...*** PP

      AATase 294 lTpflqavffvalyklgklfkeknsevsidvaipvntRrylpedeevrdsykYgtvvggseFsylissldieedskekl....welveeyhkrlsesls 388
                 lT+ +q +f  +l     l+  + s +  d a  ++  r+lp+d    d+ + gt v   +F+    s+d + +s + +    we + + +  +++ ++
  EEA19469.1 279 LTAAVQTIFASSLFV--HLPSSQFSSLYCDGA--MSFTRWLPVDLV--DKDSIGTWVSQYNFEHRFVSMDSSSQS-DAIklfsWEEARKVKATIQKEID 370
                 *************98..489888888888876..67789****987..999***********9999888886655.33311347777777777777777 PP

      AATase 389 ngkelkglgtlildlllkyvnidkllkkkilktkrstaevsNlGlfsq.....eeeskykvkdliFsqaagslknafslnvistnsgGlnlslsvvedl 482
                 n+ + + +      ll    n++k+ k+ki k + + +e+sN+G+f        ees+++v  ++Fsq+   + +a+ +++++ n+g ln+  s ++  
  EEA19469.1 371 NEGKNSAVS-----LLKFAGNMHKFSKQKIGKPRAASFEISNIGIFGHkhqedGEESSWTVGRVVFSQSVDVVGAAIEVSLVTGNDGSLNIGFSWLDGI 464
                 766666665.....577789***********************9985444487789************************************9998876 PP

      AATase 483 l 483
                 +
  EEA19469.1 465 V 465
                 5 PP

>> Condensation  Condensation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   7.9e-07    0.0071      44     155 ..      57     177 ..      21     183 .. 0.74
   2 !    3.7   0.0    0.0022        20     228     260 ..     256     288 ..     240     299 .. 0.86

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 7.9e-07
                   HHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T..TSSSHHHH......HHHHHHHHHTC--SCCCS..-SEEEEEEE..SSTTE CS
  Condensation  44 lekalqelierhdaLRtvfleeengepvQvileerevelevleisdleeseeeea......ieefaqkdlqepfdLekg..pLfraalfk..iaenr 130
                   + +al+e+i  h+aL + ++ +++ +p+ v l++ +++  v+ i  ++   +  +      ++ +++++ +++f+ +++  pL+r  ++   ++++r
    EEA19469.1  57 IYRALKEVIADHPALGVNIKDDDKSRPYYVQLPTIDLSKTVTFIPSVA-IPNPLDpegvknLDLLLEEQHNRNFKDQASqdPLWRLLIVHepVESSR 152
                   3479***************99999999988886655555444444322.22111123346699999999999998654445*****999755899** PP

                   EEEEEEEECCT--TTTHHHHHHHHH CS
  Condensation 131 lllllsvHHiivDGvSlgillrdla 155
                   ++  + +HH i DG S  ++ + l+
    EEA19469.1 153 FVACFVYHHGICDGTSGLVFHQHLH 177
                   ****************999988886 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.0022
                   EEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHH CS
  Condensation 228 lsikldeeteeklrklakeqgvtlndvllaalg 260
                    s+++++et+++l  ++++q+++l+   +++++
    EEA19469.1 256 RSVRFSQETTSQLLAACRAQSTSLTAAVQTIFA 288
                   578999********************9999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (488 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       540  (0.0301188); expected 358.6 (0.02)
Passed bias filter:                      455  (0.0253779); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.30s 00:00:00.88 Elapsed: 00:00:00.48
# Mc/sec: 3077.41
//
Query:       EEA19470.1  [L=333]
Description: aldo/keto reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.4e-46  158.3   0.0    2.8e-46  158.0   0.0    1.1  1  Aldo_ket_red  Aldo/keto reductase family
  ------ inclusion threshold ------
       0.14   11.6   0.0       0.23   10.9   0.0    1.3  1  Peptidase_S9  Prolyl oligopeptidase family


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  158.0   0.0   3.2e-50   2.8e-46       2     294 .]       8     308 ..       7     308 .. 0.92

  Alignments for each domain:
  == domain 1  score: 158.0 bits;  conditional E-value: 3.2e-50
                   EEEE-SSS-ST.TS-HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH-TTTGGG-EEEEEE--SSSTTSSSS-HHHHHHHHHHHHHHHT CS
  Aldo_ket_red   2 lglGtwqlgskeeiskeealellrraleaGinffDtAevYgkgqseellGealkksrkkreeviiatKvdlrdaeiksglskeniresleeslkrLg 98 
                   + +G+  ++  + ++ e+++++l++  e+Gi+++Dt+e+Y    seellGea +        + iatKv  + +  +   ++en+++s e+sl++L+
    EEA19470.1   8 IAYGGSVFSPSKGFTAEKSVKILEYLSENGIKTIDTSEIY--PGSEELLGEADAV----SLGFDIATKV--GAGGSPTPATRENVVRSGEASLSKLK 96 
                   77788777766999**************************..99*******8777....77999*****..999999******************** PP

                   -S-EEEEEE-S--TTS-.HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHH....HHTTT--EEEEE-B-BTT-HHHHTTHHHHHHHTT-EEEEBST CS
  Aldo_ket_red  99 tdyvDllllHrpdpslpsieevldaleelvkeGkiraiGvSnfsveqleka....kkkkkvkivavqveynllreleeegllelckkkgvpliaysp 191
                   t++vD+l++H  d  +p +ee+l+ ++el+k G  + +GvSnfs+e +e +    k+ + v +++++ +yn  ++l e++++++++k+++++ aysp
    EEA19470.1  97 TNQVDVLFIHGFDKRVP-LEETLEGFNELHKRGAFKRFGVSNFSAEEIEDVvrisKERGFVLPSVYEGNYNAIDRLIEKKIFPTIRKYNMAFYAYSP 192
                   *****************.************************************999999************************************* PP

                   TGGGTTGTTTSS---SSSCCC-------........TS-HHHHHHHHHHHHHHHH.TT--HHHHHHHHHTTS.....TT-SEEEE--SSHHHHHHHH CS
  Aldo_ket_red 192 lggGlltgkyqseedkedkeprkdlkrd........ertsknldaaeelselake.hgvslaqlalryalsq.....pavgivipgasnieqlednl 274
                   ++gG+l++     ++ +++ ++++   +         + +  l+ + ++ ++a     +s a+ a+r++ ++     + +  +i+ga+  +ql+++l
    EEA19470.1 193 IAGGFLSKTPGYIKQGGEGRWDPNT--FfgklyhamYNKPNVLEFLGKFGQIASAkAQCSQAETAYRWIAYHselkgELGDKIIIGARFGSQLTEVL 287
                   *******777666666666666653..35777887777777778888888888886888*************999999******************* PP

                   GGGG-.---HHHHHHHHHHH. CS
  Aldo_ket_red 275 dalel.klseeevaeldelle 294
                   dal+  +ls+e+v+++d l++
    EEA19470.1 288 DALKRgPLSAETVKHIDGLWD 308
                   *****************9985 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   2.6e-05      0.23     129     173 ..      87     128 ..      62     135 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 2.6e-05
                   HHHHHH-CGGG-----EEEEEEETT-SSS-THHHHHHHHHHH--S CS
  Peptidase_S9 129 kelspyspldnvkaypplLlihGlaDdrvppaealklvaaLqkkg 173
                   +  +++s+l+   +++++L+ihG  D+rvp++e+l+ +++L k+g
    EEA19470.1  87 SGEASLSKLKT--NQVDVLFIHGF-DKRVPLEETLEGFNELHKRG 128
                   34455555555..9*********5.*****************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (333 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       453  (0.0252663); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.29s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 2236.39
//
Query:       EEA19471.1  [L=230]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.6e-14   53.2   6.9    2.6e-14   53.2   6.9    1.7  2  WSC         WSC domain


Domain annotation for each model (and alignments):
>> WSC  WSC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.2   6.9   1.4e-18   2.6e-14       2      82 .]      19      97 ..      18      97 .. 0.92
   2 ?   -2.2   0.1      0.27   4.8e+03      44      44 ..     171     171 ..     140     191 .. 0.57

  Alignments for each domain:
  == domain 1  score: 53.2 bits;  conditional E-value: 1.4e-18
         WSC  2 lGCytdssesrrllgpssasdstmtpekCaafCkakgykyagledgseCyCgnslpaaavkassssCnasCsGdssqtCGg 82
                lGC+td+ +++ + + ++  +  ++++ C+++C + g +y++l+  ++C+Cg+ +p+ +   + s+C++sC+G+ +q CGg
  EEA19471.1 19 LGCFTDR-SETLSNFVNNGFYVFQSMGYCQQACDSMGHSYYALKG-TDCWCGDAIPPISDMVDHSNCDISCAGYVKQNCGG 97
                7******.56666667789999**********************5.5*********************************8 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.27
         WSC  44 l 44 
                 +
  EEA19471.1 171 T 171
                 1 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (230 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       974  (0.0543254); expected 358.6 (0.02)
Passed bias filter:                      384  (0.0214178); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.31s 00:00:00.87 Elapsed: 00:00:00.49
# Mc/sec: 1421.87
//
Query:       EEA19472.1  [L=855]
Description: annexin ANXC4 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    3.2e-12   46.3   3.1      0.012   15.7   0.0    4.6  4  Annexin     Annexin
  ------ inclusion threshold ------
       0.01   15.8   1.5       0.01   15.8   1.5    2.4  2  DUF3915     Protein of unknown function (DUF3915)


Domain annotation for each model (and alignments):
>> Annexin  Annexin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.4   0.0   0.00025       2.3       2      43 ..     532     574 ..     531     577 .. 0.85
   2 !   14.0   0.1   4.4e-06      0.04      16      58 ..     625     668 ..     617     676 .. 0.86
   3 !   15.7   0.0   1.3e-06     0.012       6      53 ..     701     748 ..     696     761 .. 0.82
   4 !    5.3   0.1    0.0024        21      29      54 ..     804     829 ..     771     831 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00025
                 HHHHHHHHHSSSS.SCHHHHHHHHHHSTHHHHHHHHHHHHHHH CS
     Annexin   2 dAelLkkamkglG.tdektlieIlatRsnaqlqaifeeYkkky 43 
                 dA  Lk+a+++    d   l+eIl + s  q+   ++eYkk+ 
  EEA19472.1 532 DAVALKDALSRHTsLDTRPLMEILPNLSSDQILTLRAEYKKHA 574
                 6778888888887467778*********************986 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 4.4e-06
                 CHHHHHHHHHHSTHHHHHHHHHHHH.HHHSS-HHHHHHHHS-HH CS
     Annexin  16 dektlieIlatRsnaqlqaifeeYk.kkygkdLekdIksetsGd 58 
                 + + lie l+ Rsna++++i+  ++ ++y  +Lek  k e++ d
  EEA19472.1 625 RRELLIESLIGRSNAEIREIKSCFRdARYADSLEKCMKAELKAD 668
                 456799******************8358************9987 PP

  == domain 3  score: 15.7 bits;  conditional E-value: 1.3e-06
                 HHHHHSSSSSCHHHHHHHHHHSTHHHHHHHHHHHHHHHSS-HHHHHHH CS
     Annexin   6 LkkamkglGtdektlieIlatRsnaqlqaifeeYkkkygkdLekdIks 53 
                 L++a+   +  e+++i+I+  R+ a+l+++++ Y + y+ +  kd+ +
  EEA19472.1 701 LRRAVASREGGETAMIDIVLLRNDAHLREVMRLYDHAYKSNFAKDVIK 748
                 5666666666799***************************99999865 PP

  == domain 4  score: 5.3 bits;  conditional E-value: 0.0024
                 HHHHHHHHHHHHHHHSS-HHHHHHHH CS
     Annexin  29 naqlqaifeeYkkkygkdLekdIkse 54 
                 +++l+ ++eeY+ +y++  e+ I +e
  EEA19472.1 804 PKHLELVKEEYRYRYKERVEEGIAQE 829
                 68***************999999877 PP

>> DUF3915  Protein of unknown function (DUF3915)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.9      0.46   4.1e+03      18      43 ..      83     109 ..      70     123 .. 0.50
   2 ?   15.8   1.5   1.1e-06      0.01       9      52 ..     466     510 ..     459     547 .. 0.70

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.46
     DUF3915  18 hccdrdre.rererederekerekkke 43 
                   +d d e r +er +er    + +++
  EEA19472.1  83 DLSDSDEEyRAKERAKERYYHSDSEDD 109
                 444544442333444444444444444 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 1.1e-06
     DUF3915   9 edfrechrg.hccdrdrerererederekerekkkerhavcnvla 52 
                  d+r  h++ +++d  +erere+e+e eke+e++++ ++   v  
  EEA19472.1 466 SDLRRKHKSsRSIDERKEREREKEREIEKEKERRRHSRHSSHVGE 510
                 467777764156677777777777777777777766666555543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (855 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1595  (0.088962); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.89u 0.33s 00:00:01.22 Elapsed: 00:00:00.45
# Mc/sec: 5687.53
//
Query:       EEA19473.1  [L=532]
Description: high-affinity nicotinic acid transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      6e-31  107.6  26.8      6e-31  107.6  26.8    1.7  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
       0.24   10.8   1.8       0.45   10.0   0.0    2.3  3  DUF1129   Protein of unknown function (DUF1129)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  107.6  26.8   6.7e-35     6e-31       1     352 [.      82     456 ..      82     457 .. 0.83
   2 ?   -0.6   0.2     0.054   4.8e+02     324     351 ..     460     488 ..     453     491 .. 0.46

  Alignments for each domain:
  == domain 1  score: 107.6 bits;  conditional E-value: 6.7e-35
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll.fasslwlllvlrvlqGlg 98 
                 l++ ++l++l+ s++g +       d ++++++++l+lt y++++a +  p   l+ ++G+r +l   ++++++  +l++ ++ s+   +++r++ G++
  EEA19473.1  82 LFIFYLLNSLDKSNAGNIKIYSFLADTNMTGTQFNLALTWYFFTYAGLEAPSNMLMRKYGARLWLSGLVTCWGAV-TLGSaWVKSYGDYCAARIMLGAF 179
                 68999999*****99999988666888****************************************99999999.5555486555579********** PP

       MFS_1  99 agalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg......Wravfyilaivsllafvlfllllpeepperkrkspkeee... 188
                 +++lf ++ + ++ w+ ++e  +  +++++++ l+ ++g ll+ ++  + g      W+++f+i ++v++++++l   + ++++ ++k+ s++ ++   
  EEA19473.1 180 EAGLFQGCFYTLSCWYLPTELQSRCAWWYSATMLSGAFGGLLAYAVGPLQGhlgnkqWQYLFFIEGAVTIFFGLL--GFWLCPDFPEKWGSKWFKKdem 276
                 ***********************************************88888**********************9..7777788888888888887789 PP

       MFS_1 189 ........kgtgpaplvp..awkallkdpvlw....illialllfffgfsglltllplylqevlgls..glllaglllallalvgailallagrlsdrl 271
                          ++gp p  +  +w+all     w    i+ + ++++++ ++++ ++l + +++ lg++     +a+   a +++++++  +l++++sd++
  EEA19473.1 277 rylqlrvkYKDGPVPPDDtfHWGALLEAIKDWktyfIASLLAFGGSVPTYSVNYTLAT-MVKSLGYTsiR-AQAL--TAPPYVFAFVCVILIAWYSDKY 371
                 9999987755555555557766666665555664223333333334444449999999.6*******642.4555..7777777777788********* PP

       MFS_1 272 grrrrlllallllllaalglallavtssavllll..vlvliGfglgfvfpsllalasdla.ppeeagtasglfntags.lggalg 352
                 + r+r ll+   + ++ +++++ +++++++ +l   +l+l+  g+ +  p++ +++  ++  p+++++a+g+ +t g+ +gg++g
  EEA19473.1 372 QCRCRSLLISYTIGTIGIIILWPSLYHKNLSGLSyfALFLVVAGYNMQAPAVGSWLGTNVrNPSKRAAAMGWQSTWGQlFGGCIG 456
                 **************************5555555543777777799999999999999999777**************98888887 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.054
       MFS_1 324 lasdlappeeagtasglfn.tagslggal 351
                 ++s+ ap+ ++g+++ l+  ++g++g+++
  EEA19473.1 460 FVSSEAPTYHSGFITLLVLvIVGGFGACI 488
                 44444444444444444443444444443 PP

>> DUF1129  Protein of unknown function (DUF1129)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.1      0.17   1.6e+03     120     158 ..     182     218 ..     172     226 .. 0.65
   2 ?   -3.9   0.2       0.9   8.1e+03     108     127 ..     399     418 ..     379     423 .. 0.63
   3 ?   10.0   0.0     5e-05      0.45      97     143 ..     456     503 ..     430     509 .. 0.79

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.17
     DUF1129 120 alvgGlamvlvyrlltrekkkkkrpplwkrllilllllv 158
                 +l  G++++l   +l +  + ++r  +w ++++l +++ 
  EEA19473.1 182 GLFQGCFYTLSCWYL-P-TELQSRCAWWYSATMLSGAFG 218
                 444455554444444.3.789999999999999888765 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 0.9
     DUF1129 108 tasiGlitlllvalvgGlam 127
                 ++ +Gl + +l+ +v+G+ m
  EEA19473.1 399 KNLSGLSYFALFLVVAGYNM 418
                 33357777777777777766 PP

  == domain 3  score: 10.0 bits;  conditional E-value: 5e-05
     DUF1129  97 gilalfskkkqtas.iGlitlllvalvgGlamvlvyrlltre.kkkkkr 143
                 g   ++s +++ ++ +G+itll++ +vgG+   + + +  r  + kk++
  EEA19473.1 456 GANIFVS-SEAPTYhSGFITLLVLVIVGGFGACIANWYCLRAsNLKKDK 503
                 5545455.5666666****************999999998865445555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (532 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       653  (0.0364214); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.30s 00:00:00.93 Elapsed: 00:00:00.49
# Mc/sec: 3295.72
//
Query:       EEA19474.1  [L=765]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.8e-08   33.8   4.0      5e-08   32.9   4.0    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.029   13.4   0.0      0.077   12.0   0.0    1.7  1  Fungal_trans  Fungal specific transcription factor domain
       0.12   13.0   0.6       0.86   10.3   0.1    2.2  2  SlyX          SlyX


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.9   4.0   8.4e-12     5e-08       1      34 [.      51      89 ..      51      94 .. 0.84

  Alignments for each domain:
  == domain 1  score: 32.9 bits;  conditional E-value: 8.4e-12
                SS-HHHHHCT---STSSSS.....-HHHHHCTHHHCCCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPa.....CsnCkklnleCtfys 34
                +aC++Cr +K +C +  P+     Cs+C+ l++eC+f +
  EEA19474.1 51 KACIQCRVRKQRCGGLSPEtptasCSRCIHLGVECSFTT 89
                59*************5555555**************544 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   1.3e-05     0.077       2     157 ..     278     434 ..     277     458 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 1.3e-05
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilq.sL 97 
                   d+ff  +h++ p+l  +++ +        + + a p l+++i+a++ +f++   +   + ++ ++   i +    + l+  +  s +  l ++q  L
    EEA19474.1 278 DLFFASCHNWAPVLCPQTQKSAA------SVRLACPTLFTSICAVAFRFMDPFPSAGLQHREIVK---ILDVSLGRLLL-KPDLSDVH-LGHIQaIL 363
                   78**************9999999......99*******************998888755555544...43334566666.34444555.9****777 PP

  Fungal_trans  98 lllelyektssd..ralher..........hhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlww 157
                   l++++    +++     h r          ++g+a+r a  lgL++ ps   +++    ++e   +r R+w 
    EEA19474.1 364 LYVQWMPVDMQNggLQDHPRtryndvsawsMLGLAIRYALFLGLQDSPSAFLPERQASATVE-DLARLRVWI 434
                   888888888886445555557888888888*******************9998874444444.333444444 PP

>> SlyX  SlyX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.1   0.00014      0.86      10      43 ..     103     136 ..     102     152 .. 0.85
   2 ?    0.1   0.1      0.22   1.3e+03       5      27 ..     576     598 ..     574     601 .. 0.69

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00014
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        SlyX  10 iklafqedtieeLndvvaeqqqqidrlqrqlrll 43 
                 +k+a + +++++L++ vaeq++++ rl+r   +l
  EEA19474.1 103 TKVAKTAHVLDRLQKRVAEQEDRLRRLERITSHL 136
                 6889999999999999999999999999987777 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.22
                 HHHHHHHHHHHHHHHHHHHHHHH CS
        SlyX   5 leeLEiklafqedtieeLndvva 27 
                 +e+L + l+   +ti +L+++v+
  EEA19474.1 576 IEALDVSLTAACQTILALSEQVT 598
                 67777777777777777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (765 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       562  (0.0313459); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.44
# Mc/sec: 5210.06
//
Query:       EEA19475.1  [L=336]
Description: alpha-ketoglutarate-dependent 2,4-dichlorophenoxyacetate dioxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      3e-43  148.6   1.7    3.6e-43  148.3   1.7    1.0  1  TauD      Taurine catabolism dioxygenase TauD, TfdA family
  ------ inclusion threshold ------
        2.3    8.4   4.8       0.63   10.2   0.8    2.2  2  ABM       Antibiotic biosynthesis monooxygenase


Domain annotation for each model (and alignments):
>> TauD  Taurine catabolism dioxygenase TauD, TfdA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  148.3   1.7   4.1e-47   3.6e-43       3     267 ..      12     294 ..      10     295 .. 0.85

  Alignments for each domain:
  == domain 1  score: 148.3 bits;  conditional E-value: 4.1e-47
        TauD   3 kpltpk.fgae..gvdlsdleslddelkeelrellaeygvvvfrgfplspeqqlefarrfG..plygtpgrgtntkygevldvssvyesadianlaytt 96 
                  p+ ++ fgae  g++++++ +l d++ ++l  l ++y +++fr+++l+++ +++f++ +G  +l    g +t+ ++  ++dvs+ +++++ a     +
  EEA19475.1  12 APILNNsFGAEvsGINWDQV-PLPDATIKTLITLQNKYAIIIFRNTNLDNDRHVAFSQQLGalELNPVWGNTTRVNNQYLFDVSNLEADGSVAK--RGS 107
                 5666667************7.78889999999999**************************665555556666666666666444333333333..222 PP

        TauD  97 ll.........wHtDlsylesppgiqlLhcleapatG.GetpfvDgraaynaLpeelpellegltavrvyyhyrg...gglrteqelpavdkhprtghp 182
                 ++         wHtD++++++ ++++lL ++ +p +G G t+f+D+r+a+++L+ee++ +l+   +++   h+r+    ++ +e +++++ k+p++ h 
  EEA19475.1 108 RRwahslgnalWHTDSAFNQHRAKYSLLLAHSVPGEGkGKTTFADTRRAWRELDEERKGELKDVVVEHELWHSRRlaaPEEYSELTPEERGKKPPAYHR 206
                 22444456666*******************************************************************9999999************** PP

        TauD 183 vvrthpvltgrkallvnppfatri...eglgtpeskelldaleelledpeftyrfqwqe.GdlvifdNrrvlHgrtafdeg.eeRhllrc 267
                 +v++ p+  ++++++   ++a+r+   +g + ++s++ +  l ++++++++t+  +w+  Gdl+ +dNr  +H+++a+de+   R ++r 
  EEA19475.1 207 LVQRTPN-GEEETFFLA-AHAKRLfskDGEELEDSQKKIWDLIAHCTQDKYTFVAEWKSaGDLMWWDNRQSMHRASAYDEKmGARDVRRS 294
                 ******6.888999998.99999988899999999999999999**************99******************655345777775 PP

>> ABM  Antibiotic biosynthesis monooxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.2       0.5   4.4e+03      57      68 ..     119     130 ..     117     138 .. 0.85
   2 ?   10.2   0.8     7e-05      0.63      48      77 ..     252     281 ..     249     282 .. 0.92

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.5
                 ESSHHHHHHHHT CS
         ABM  57 Weseaaleahlk 68 
                 W +  a+++h++
  EEA19475.1 119 WHTDSAFNQHRA 130
                 99999***9997 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 7e-05
                 TTEEEEEEEESSHHHHHHHHTSHHHHHHHH CS
         ABM  48 pdevvvieeWeseaaleahlksphfkaahe 77 
                 +d++++++eW+s+ +l ++ + +++++a++
  EEA19475.1 252 QDKYTFVAEWKSAGDLMWWDNRQSMHRASA 281
                 5899**********************9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (336 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       570  (0.0317921); expected 358.6 (0.02)
Passed bias filter:                      446  (0.0248759); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2356.04
//
Query:       EEA19476.1  [L=575]
Description: septin [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      1e-33  116.9   0.1    1.1e-11   44.6   0.0    3.2  3  Septin          Septin
     0.0005   19.5   0.0     0.0011   18.4   0.0    1.5  1  FtsK_SpoIIIE    FtsK/SpoIIIE family
    0.00086   19.1   4.0    0.00086   19.1   4.0    1.4  2  BSP_II          Bone sialoprotein II (BSP-II)
     0.0017   16.8   0.9     0.0017   16.8   0.9    1.9  2  CDC45           CDC45-like protein
     0.0082   15.9   5.5     0.0082   15.9   5.5    1.9  2  DUF4637         Domain of unknown function (DUF4637)
  ------ inclusion threshold ------
      0.026   14.3   0.0      0.068   12.9   0.0    1.7  1  AAA_15          AAA ATPase domain
      0.038   14.1   0.0      0.093   12.8   0.0    1.7  1  MMR_HSR1        50S ribosome-binding GTPase
      0.053   13.6   4.2       0.21   11.6   0.2    2.9  2  Dynamin_N       Dynamin family
      0.063   13.7   0.1       0.75   10.2   0.0    2.5  2  AAA_16          AAA ATPase domain
      0.066   12.4   0.0       0.15   11.2   0.0    1.6  1  G-alpha         G-protein alpha subunit
       0.29    9.3  11.5        0.5    8.5  11.5    1.3  1  Nop14           Nop14-like family
        0.3   11.2  12.2      0.087   12.9   6.3    2.2  2  DUF2052         Coiled-coil domain containing protein (DUF205
        2.9    6.3   8.6        4.2    5.8   8.6    1.1  1  RRN3            RNA polymerase I specific transcription initi
        5.1    5.1  17.4        7.4    4.5  17.4    1.1  1  DNA_pol_phi     DNA polymerase phi


Domain annotation for each model (and alignments):
>> Septin  Septin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.1   0.0   3.3e-12   4.3e-09       5     123 ..     185     310 ..     182     315 .. 0.79
   2 !   32.3   0.2   4.7e-11     6e-08     129     195 ..     343     409 ..     337     417 .. 0.85
   3 !   44.6   0.0   8.5e-15   1.1e-11     189     276 ..     464     551 ..     427     556 .. 0.83

  Alignments for each domain:
  == domain 1  score: 36.1 bits;  conditional E-value: 3.3e-12
                 EEEEEEEBTTSSCCCCCCTTSSSS----.....--------..------S-EEEEEEEEETTCEEEEEEEE---BSSSSSHHCCCHHHHHHHHHHHHHH CS
      Septin   5 ftlmvvGesglGkttlintlfetdliee.....ekleease..kkkktveikkkkvvieedgvklnltviDtpgfGdavdnskswepiveyideqfeey 96 
                 ++l+vvG++  Gkt+++n l ++   +      ++ e+  e  +++++ ++ ++  + e +g ++ lt+ D +g   +v  +   + i  +++++fe+ 
  EEA19476.1 185 YNLLVVGAKNSGKTSFLNFLRKSLALPPnklpiRSSEDILEeiNSSSNPNFISHYLETEIEGERVGLTLWDSEGLDKNVV-DLQLRDITAFLESKFEDT 282
                 79****************9998877666566664444443412333444555555666667889***********87774.556899************ PP

                 HHHCTSS--.SS-----EEEEEEEE-TT CS
      Septin  97 lreesklkR.kkivDkRvHaclyfisPt 123
                 l ee k+ R     D+ +H+++++++P+
  EEA19476.1 283 LMEEMKVVRsPGARDTHIHCVFWILDPV 310
                 *********8889************997 PP

  == domain 2  score: 32.3 bits;  conditional E-value: 4.7e-11
                 HHHHHHHHHHTTTS-EEEEESSGGGS-HHHHHHHHHHHHHHHHHTT--------SSSS-SCCHHHHH CS
      Septin 129 pldvelmkklsekvnliPviaKaDtltkeElkefKkkireeleeeeikiyklpdeeededeeakels 195
                 ++d+++++ ++ k  ++Pvi+KaDt+t+  +  +Kk + ++l++  i+  ++   ee e+ee  e++
  EEA19476.1 343 DIDLQFLRVMQGKTAVVPVISKADTITTAHMAYLKKAVWDSLKQARIDPLEVLILEEAEEEEEGEEE 409
                 79*********************************************99997666666655544444 PP

  == domain 3  score: 44.6 bits;  conditional E-value: 8.5e-15
                 CCHHHHHHHHHHC-SEEB-SSSSEEEESSSEEEEEEETTEEEETT-TTT-SCCHHHHHHHHHCHHHHHHHHHHTHHHHHHHHHH-XXX CS
      Septin 189 eeakelseklkeslPfaivgsneliekkgkkvrgRkypWGvvevenekhsdFlkLrklllkthledLkevteellYetyRseklsklk 276
                 + ++ +s + +  +P +i++ +    +  +   gR++pWG  + +n++h+dF+kL++ +++ +  +L+e  +e+ Ye++R+++l+ ++
  EEA19476.1 464 NSISITSTTDTPFIPLSILSPDPHSLDTPNLPVGRHFPWGYADPYNPEHCDFVKLKESVFRDWRAELREASREVCYERWRTSRLNIKQ 551
                 444445555556688899988888888888899**************************************************98766 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.0   8.3e-07    0.0011      37      65 ..     180     210 ..     149     216 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 8.3e-07
                   GS-...SEEEE--TTSSHHHHHHHHHHHHHT CS
  FtsK_SpoIIIE  37 kma..shllvaGatgsGKStalntLilSlat 65 
                   k +   +llv+Ga+ sGK+ +ln L  Sla+
    EEA19476.1 180 KDPtpYNLLVVGAKNSGKTSFLNFLRKSLAL 210
                   444448*******************999997 PP

>> BSP_II  Bone sialoprotein II (BSP-II)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   0.3       7.1   9.1e+03     128     131 ..      72      75 ..      33      95 .. 0.42
   2 !   19.1   4.0   6.8e-07   0.00086     138     235 ..     399     493 ..     356     514 .. 0.64

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 7.1
      BSP_II 128 ekat 131
                 ++++
  EEA19476.1  72 SNGK 75 
                 1111 PP

  == domain 2  score: 19.1 bits;  conditional E-value: 6.8e-07
      BSP_II 138 eeeeeeeeeeneeeeaevdeneqgvngtstnsteaengngssggdngeeeeeesvteaeaegteveeeeeagsaetttspnglfeatt...plqeaydt 233
                 e eeeee ee+e++ea  de+e++     t  +e   ++ s++  + e +e+ +v+e+  + + ++++++++s++ t ++++ f + +   p ++  dt
  EEA19476.1 399 EAEEEEEGEEEEDSEAATDEDENS---DVTPVAE---DETSEDKAEAETDEDAEVQEKAPKASPTRSHKSNNSISITSTTDTPFIPLSilsPDPHSLDT 491
                 445555556888999999998864...2233333...33333333445556666666666666777777888888887777766543322255555555 PP

      BSP_II 234 tt 235
                   
  EEA19476.1 492 PN 493
                 55 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   3.5       1.1   1.4e+03     161     213 ..      42      94 ..      26     108 .. 0.37
   2 !   16.8   0.9   1.3e-06    0.0017     125     193 ..     382     460 ..     270     539 .. 0.61

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 1.1
       CDC45 161 eedeeeskkkrksksdeeee.....sddddersrkrrrse.psakklrrq..lkkerrkye 213
                  ++++++++++        +     ++++ e+ ++r+ s+ + ++k+++q  ++++rr+ e
  EEA19476.1  42 ANNSDTASRRS--------SlgflrRSKSTEPLSERKSSNgKISRKMKEQmrEEELRRQRE 94 
                 22222222222........122232222223333333333233333333332222222222 PP

  == domain 2  score: 16.8 bits;  conditional E-value: 1.3e-06
       CDC45 125 aleeeeesd...........eedeeeeeeddddeeeeeeeeedeedeeedeeeskkkrksksdeeee.sddddersrkrrr 193
                    ++   d           ee+e eeeed++   +e+e+++ +   e++++e+  k ++++de+ e ++++ + s  r++
  EEA19476.1 382 DSLKQARIDplevlileeaeEEEEGEEEEDSEAATDEDENSDVTPVAEDETSED--KAEAETDEDAEvQEKAPKASPTRSH 460
                 333444443333333211101121111111111111112112222222222221..2222222222222222222222222 PP

>> DUF4637  Domain of unknown function (DUF4637)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   1.1       4.5   5.7e+03      48      77 ..      39      67 ..      27      95 .. 0.55
   2 !   15.9   5.5   6.4e-06    0.0082      11      87 ..     399     477 ..     391     499 .. 0.57

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 4.5
     DUF4637 48 sreaeeaegrekgsvsysPlrqessaqeva 77
                + +a+++++  ++s s   lr+  s++ ++
  EEA19476.1 39 RLSANNSDTASRRS-SLGFLRRSKSTEPLS 67
                44444555443333.444555555554443 PP

  == domain 2  score: 15.9 bits;  conditional E-value: 6.4e-06
     DUF4637  11 elear.eveeeeaeeeseeedeeedrae.eesaaege.eesreaeeaegrekgsvsysPlrqessaqevallrradsgfw 87 
                 e e++ e eeee++e   +ede++d ++  e ++ ++ +e++  e+ae + +++   sP r   s + +++   +d+ f 
  EEA19476.1 399 EAEEEeEGEEEEDSEAATDEDENSDVTPvAEDETSEDkAEAETDEDAEVQ-EKAPKASPTRSHKSNNSISITSTTDTPFI 477
                 33333033344444444445554443331233333331333334444445.566778*************9999998884 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   5.3e-05     0.068      27     165 ..     188     469 ..     181     478 .. 0.64

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 5.3e-05
      AAA_15  27 vliGkNnsGKSsilealdlFlnnkekkn......kkvikiekedleifeniseskdikIdvef.................................... 83 
                 +++G+ nsGK+s+l++l + l      n      ++ i +e ++ ++ + is+  + +I+ e                                     
  EEA19476.1 188 LVVGAKNSGKTSFLNFLRKSLALPP--NklpirsSEDILEEINSSSNPNFISHYLETEIEGERvgltlwdsegldknvvdlqlrditafleskfedtlm 284
                 78***************66555432..145676633444444444444455555555555555666666677777666666666666666666688888 PP

      AAA_15  84 ................................................................................................... 83 
                                                                                                                    
  EEA19476.1 285 eemkvvrspgardthihcvfwildpvrldsnlaaaqkaagqadgkytnasrvvgildedidlqflrvmqgktavvpviskadtittahmaylkkavwds 383
                 888888888888888888888888888888888888888888888888888888888888888888888888888888888888888888888888887 PP

      AAA_15  84 ..............aekekakeyektlkskekkkadlllkkkesdlkktikdkklklkknelsdekisvekkkskkelpkekeeklekekeelkid 165
                               +   +a+e  +++ ++e++++    ++++sd     +d++ ++k++  +de  +v++k      pk +   ++k++++++i+
  EEA19476.1 384 lkqaridplevlilE---EAEE--EEEGEEEEDSEAATDEDENSDVTPVAEDETSEDKAEAETDEDAEVQEK-----APKASPTRSHKSNNSISIT 469
                 777765555444331...1222..222222222223334555555555555555555555555555555554.....5556666666666666665 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   7.3e-05     0.093       2      55 ..     187     258 ..     186     327 .. 0.66

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 7.3e-05
                 EEEEESTTSSHHHHHHHHHTSTE.EESSSTTSSSSEEEEEEEETTEE.................EEEEECGG CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltgeka.ivsdkpgtTrdinegrvklkgke.................ielvDtpG 55 
                  ++vG  N+GK++++n l ++ a   ++ p    + + ++++ + ++                 ++l+D  G
  EEA19476.1 187 LLVVGAKNSGKTSFLNFLRKSLAlPPNKLPIRSSEDILEEINSSSNPnfishyleteiegervgLTLWDSEG 258
                 579***************998551445555555555555454222223444444444444444466666666 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.2   0.00017      0.21       2      28 ..     188     214 ..     187     299 .. 0.92
   2 ?    2.1   0.5      0.14   1.7e+02      30      90 ..     368     465 ..     352     494 .. 0.44

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00017
                 EEEEBTTTTHHHHHHHHHTS--S---S CS
   Dynamin_N   2 avvGsqSsGKSSvlnaLlgedilprgp 28 
                 +vvG+ +sGK+S+ln L ++  lp  +
  EEA19476.1 188 LVVGAKNSGKTSFLNFLRKSLALPPNK 214
                 7**************998888887655 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.14
                 S---S-EEEEE...........................CCT---CCS...SSEEEET-EB--CHHHHHHHHHHHHHHHT..SSSS--SS.......... CS
   Dynamin_N  30 ptTrrplelql...........................geeeeaseravkeelkekekkledfsevreeieketekiag..ankgiskk.......... 89 
                 +tT+ +  l++                           g      e++++ e   +e++ +d++ v+e  ++e +  a+  +  ++++k          
  EEA19476.1 368 ITTAHMAYLKKavwdslkqaridplevlileeaeeeeeG------EEEEDSEAATDEDENSDVTPVAEDETSEDKAEAEtdEDAEVQEKapkasptrsh 460
                 555555555556666666565555555555443322221......222222222224444444444433333333322200222222223333333444 PP

                 ....- CS
   Dynamin_N  90 ....v 90 
                      
  EEA19476.1 461 ksnnS 465
                 44440 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   0.00059      0.75      16      49 ..     176     209 ..     174     225 .. 0.90
   2 ?   -0.1   0.2      0.81     1e+03      36     107 ..     354     431 ..     353     467 .. 0.45

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00059
      AAA_16  16 lervrsgrpelvllsGesGvGKsslvrellrale 49 
                 l+r ++++p ++l++G++ +GK+s ++ l+++l 
  EEA19476.1 176 LRRRKDPTPYNLLVVGAKNSGKTSFLNFLRKSLA 209
                 7888899999******************999875 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.81
      AAA_16  36 GKsslvrellr..alekdg.giflrgkcdqlesaipysalaqalareellrqlldeaesaeleawrekleeala..........a 107
                 GK+++v  + +   +++++ +++ ++ +d+l++a       ++   e l+ ++++e+e+ e e+++e+ +++ +          +
  EEA19476.1 354 GKTAVVPVISKadTITTAHmAYLKKAVWDSLKQA-------RIDPLEVLILEEAEEEEEGEEEEDSEAATDEDEnsdvtpvaedE 431
                 6666664444322344444344444555555222.......22222233333333333333333333333322244344333331 PP

>> G-alpha  G-protein alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   0.00011      0.15      12      44 ..     172     205 ..     162     242 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00011
                 XXXXXXXXE...EEEEEEEESTTSSHHHHHHHHH CS
     G-alpha  12 kaerkarkk.krevkllllGqseSGKsTilkqlk 44 
                    r +r+k  ++++ll++G++ SGK+++l+ l+
  EEA19476.1 172 SPRRLRRRKdPTPYNLLVVGAKNSGKTSFLNFLR 205
                 44455555567899****************9877 PP

>> Nop14  Nop14-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5  11.5   0.00039       0.5     374     433 ..     399     464 ..     371     480 .. 0.40

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00039
       Nop14 374 eedeeeeedeeeeeeeeededdlsdlese......eeeeedeleeelleeekkaaeekkekkkkkk 433
                 e +eeee +eee++e+ +ded++sd          e++ e e +e+++++ek  +++ ++++k+++
  EEA19476.1 399 EAEEEEEGEEEEDSEAATDEDENSDVTPVaedetsEDKAEAETDEDAEVQEKAPKASPTRSHKSNN 464
                 222222222222222223333333332221111112222222222221222211111111112222 PP

>> DUF2052  Coiled-coil domain containing protein (DUF2052)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.3      0.22   2.8e+02      56      80 ..      71      95 ..      33     163 .. 0.56
   2 ?   12.9   6.3   6.8e-05     0.087      81     142 ..     391     457 ..     320     472 .. 0.53

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.22
     DUF2052 56 slseiLlrreeeaaaaerleaqqee 80
                s    + r+++e++++e l++q+e+
  EEA19476.1 71 SSNGKISRKMKEQMREEELRRQRES 95
                1112222222222222222222222 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 6.8e-05
     DUF2052  81 l.........eeeeeeeeeeeeeeeeeeeeeeedekekaeadeedeeeeeekeekeeeeekeeeaeaevls 142
                           eeeee eeee++e ++ +e+e+ d ++ ae   ++ +e+++++e++e++e +e+a +++++
  EEA19476.1 391 PlevlileeaEEEEEGEEEEDSE-AATDEDENSDVTPVAE---DETSEDKAEAETDEDAEVQEKAPKASPT 457
                 14444543211222222222222.2222233222222222...2222222223344444444444433333 PP

>> RRN3  RNA polymerase I specific transcription initiation factor RRN3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   8.6    0.0033       4.2     194     267 ..     376     449 ..     340     467 .. 0.56

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0033
        RRN3 194 lsedileliverlik.iDVeiqveledlddeedeeleeeleededdedddedd...eesdlddlssdeeaeedeekde 267
                 l++ +++ + +  i+ + V i  e e+ ++ e+ee++e+     +ded+++d    +e+++++++ ++e +ed+e +e
  EEA19476.1 376 LKKAVWDSLKQARIDpLEVLILEEAEEEEEGEEEEDSEA----ATDEDENSDVtpvAEDETSEDKAEAETDEDAEVQE 449
                 566666655433222244555555555555555544433....33444444444443333333333333333333222 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5  17.4    0.0058       7.4     639     692 ..     401     450 ..     383     468 .. 0.54

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.0058
  DNA_pol_phi 639 edededeeddeeeeeeddeededse..edddeeesdedeededdedvdeidelrek 692
                  e+e+e ee++++e+ +d++e++d++   +d+ +e++ + e+++d++v+e      k
   EEA19476.1 401 EEEEEGEEEEDSEAATDEDENSDVTpvAEDETSEDKAEAETDEDAEVQE------K 450
                  2333333333333333444444444654444455555555555555555......3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (575 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1314  (0.0732891); expected 358.6 (0.02)
Passed bias filter:                      636  (0.0354733); expected 358.6 (0.02)
Passed Vit filter:                       132  (0.00736237); expected 17.9 (0.001)
Passed Fwd filter:                        29  (0.00161749); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.81u 0.32s 00:00:01.13 Elapsed: 00:00:00.45
# Mc/sec: 3833.27
//
Query:       EEA19477.1  [L=339]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-12   46.6   4.0    1.8e-12   46.4   2.2    1.8  2  Vps62     Vacuolar protein sorting-associated protein 62


Domain annotation for each model (and alignments):
>> Vps62  Vacuolar protein sorting-associated protein 62
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0      0.02   3.6e+02     237     269 ..      37      69 ..      25      91 .. 0.80
   2 !   46.4   2.2     1e-16   1.8e-12     361     487 ..     161     292 ..     142     301 .. 0.80

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.02
       Vps62 237 eqikalikaygptvyfhpdeeylpssvsWffkn 269
                  q + +i   +p+v++  +e+y+p  +    +n
  EEA19477.1  37 PQEHDVIGVTAPLVWLDVNETYFPGDIYGQVQN 69 
                 5778899999**************988666665 PP

  == domain 2  score: 46.4 bits;  conditional E-value: 1e-16
       Vps62 361 lplgki.GehvgdWehvtlrisnfsgeLlsvyfsqhsgGewvdasdlefieggnkavvyssknghasypkpglv...lqGsaklgiGirndaarsklvv 455
                 + lg + G+hvgdWeh  +r +n  ge +++++sqhsgGe      +  i+  +++v ys +  ha y+  g+    + G + l  G  nd +   ++ 
  EEA19477.1 161 IVLGAVwGDHVGDWEHNMVRFTN--GEPQALWYSQHSGGEAFTYDAVLKIN--SRPVSYSGQGTHANYAIQGVHdhtIPGVN-LPFGPVNDYTSNGTLW 254
                 55665559************997..9999**********998877766666..7*****************98533377877.9*********999999 PP

       Vps62 456 Dss.....akyeivaaeylesavaeP.aWlqymreWGP 487
                 D +      +y+ v+a +   + + P +Wl +  +WG 
  EEA19477.1 255 DPTgnyyaYSYDNVTAVFTAYDSSYPvNWLYFNGQWGD 292
                 9872222234566777777555556637********95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (339 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       402  (0.0224218); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 2507.53
//
Query:       EEA19478.1  [L=403]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
        1.8    7.0  13.3        1.9    7.0  13.3    1.1  1  Macoilin       Macoilin family


Domain annotation for each model (and alignments):
>> Macoilin  Macoilin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0  13.3   0.00011       1.9     254     371 ..      98     214 ..      40     366 .. 0.54

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.00011
    Macoilin 254 eyrekkksakssrsdskkkhehnesvdsklqekeymenkskskrlsksessgsesellveesvkskssssssssnknskkasagsagssnssskkhses 352
                  +++++ s ++++ +s+++h + +s ++++++ e +  + + + ++++  + ++s+  ++ + +++  s  s+ +++ +++ ++  +  + s+   +++
  EEA19478.1  98 RHQDRSPSRRDKERSSRREHIDDSSREHHKSRSERHRRRHEGDGSESD-RDRETSSRSHRRHRDEERRSRRSRRESSRSRHRSSRYSRDKRSASPRRSR 195
                 333333334444333333333332222222222222222222222111.11122222222222222222222222222222222222222222222333 PP

    Macoilin 353 sksvtsssssknskkqklp 371
                 s+s  ss  +++++k+   
  EEA19478.1 196 SESLGSSRRHRHNDKDYER 214
                 3333333333322332222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (403 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1416  (0.0789782); expected 358.6 (0.02)
Passed bias filter:                      403  (0.0224776); expected 358.6 (0.02)
Passed Vit filter:                       101  (0.00563333); expected 17.9 (0.001)
Passed Fwd filter:                        33  (0.00184059); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.93u 0.38s 00:00:01.31 Elapsed: 00:00:00.53
# Mc/sec: 2304.46
//
Query:       EEA19479.1  [L=297]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      0.001   19.6  16.5      0.016   15.7  16.5    2.1  1  Fez1             Fez1
      0.001   18.9  11.4     0.0014   18.5   1.4    3.4  3  Prefoldin        Prefoldin subunit
     0.0026   18.0   4.6     0.0035   17.6   2.6    2.0  2  DUF948           Bacterial protein of unknown function (DUF94
  ------ inclusion threshold ------
      0.024   14.7   8.2      0.024   14.7   8.2    2.7  2  TPR_MLP1_2       TPR/MLP1/MLP2-like protein
       0.03   14.6   5.7       0.03   14.6   5.7    2.7  3  BLOC1_2          Biogenesis of lysosome-related organelles co
      0.051   14.2  18.5       0.16   12.6   1.9    3.6  3  SlyX             SlyX
      0.066   13.5  15.0       0.56   10.5   7.0    2.5  2  OmpH             Outer membrane protein (OmpH-like)
       0.14   11.1   6.4       0.63    8.9   6.4    1.9  1  Kre28            Spindle pole body component
       0.17   10.7  18.1       0.37    9.6   8.3    2.2  2  Spc7             Spc7 kinetochore protein
       0.31   10.4  12.0       0.65    9.3  12.0    1.6  1  DUF4407          Domain of unknown function (DUF4407)
       0.48   10.5   7.4       0.46   10.5   4.7    2.0  2  DUF1664          Protein of unknown function (DUF1664)
       0.54    9.8   7.0        4.5    6.9   0.2    2.7  2  TPD52            Tumour protein D52 family
       0.94    8.9  18.8        2.5    7.5   3.5    2.2  2  DUF3552          Domain of unknown function (DUF3552)
        1.1    9.0  13.0        3.4    7.5   0.9    2.6  2  DUF724           Protein of unknown function (DUF724)
        1.1    9.5   7.3        1.9    8.7   6.7    1.7  1  zf-C4H2          Zinc finger-containing protein
        1.5    9.2  17.4        1.2    9.4   9.3    3.1  2  Lzipper-MIP1     Leucine-zipper of ternary complex factor MIP
        2.3    8.9  16.8        1.3    9.6   7.9    3.1  2  BST2             Bone marrow stromal antigen 2
        2.5    8.1  16.8        2.6    8.1   0.8    3.0  3  ADIP             Afadin- and alpha -actinin-Binding
        2.6    8.3  26.5      0.087   13.1   6.6    4.8  4  ABC_tran_CTD     ABC transporter C-terminal domain
        2.7    8.0   8.7        7.6    6.6   8.7    1.9  1  DUF1043          Protein of unknown function (DUF1043)
        2.9    8.6   9.5         26    5.5   0.1    3.0  2  YabA             Initiation control protein YabA
        3.2    7.8  10.1        3.5    7.7   4.3    2.3  2  Laminin_II       Laminin Domain II
        3.3    6.7  13.4         27    3.7  13.4    2.0  1  Atg14            Vacuolar sorting 38 and autophagy-related su
        3.5    7.2  21.8        2.1    8.0  10.1    2.5  2  Lebercilin       Ciliary protein causing Leber congenital ama
        3.7    8.0  18.2        3.4    8.2   0.9    3.8  3  DUF4140          N-terminal domain of unknown function (DUF41
        3.8    8.0   7.9        1.3    9.6   1.9    2.8  3  UPF0449          Uncharacterised protein family UPF0449
        4.3    5.9  11.5         17    3.9  11.5    1.8  1  AAA_13           AAA domain
        4.6    7.2  15.1       0.57   10.2   3.6    3.4  3  Prefoldin_2      Prefoldin subunit
        5.6    7.6  15.0         12    6.6   7.2    2.8  2  HIP1_clath_bdg   Clathrin-binding domain of Huntingtin-intera
        7.6    6.7  23.6       0.99    9.6   6.6    2.6  2  CENP-Q           CENP-Q, a CENPA-CAD centromere complex subun
        7.9    6.6  15.0        5.5    7.1   1.1    3.2  3  BRE1             BRE1 E3 ubiquitin ligase
        9.7    6.3   8.2         10    6.2   5.2    2.2  2  Cob_adeno_trans  Cobalamin adenosyltransferase


Domain annotation for each model (and alignments):
>> Fez1  Fez1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7  16.5   2.9e-05     0.016      31     166 ..     112     269 ..     109     273 .. 0.70

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 2.9e-05
        Fez1  31 seivalkaqlrelrakleekeeeikeleesleektlelevcenelqrkkseaellrekvekleeelkelreelselsleeeeaa............... 114
                 +e v+l a+l e++++l+++ +e++ + e++e+  ++l +  +++q ++++ + l e++ +le+ +++l+++ ++ ++ ++ ++               
  EEA19479.1 112 NENVELEATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTKLSELPEEIAQLEQTIASLKQSQAAYAAASDPHNtssspnlslpatlkl 210
                 788999999999999999999999999999999999999999999999999999999999999999999997776655555444677888877766555 PP

        Fez1 115 .....lesdeakaqrqe...........aeeleelkreverlraeLk.eerqkkeeqassFeqERrtWq 166
                      +          e           +++l + +re e +++eL  +er+k+++  ++ e ER++ +
  EEA19479.1 211 laereA----------ElaaidrqiaslQNTLPRKTREAEAMERELGvLERRKSDAIGQAREAERKKLE 269
                 544221..........02222223344455666667777777777752566666777777777777655 PP

>> Prefoldin  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   1.4   2.5e-06    0.0014      61     116 ..     107     162 ..      72     166 .. 0.88
   2 ?    3.9   0.4     0.086        48       3      22 ..     168     187 ..     159     204 .. 0.63
   3 ?    2.3   0.2      0.26   1.5e+02      11     112 ..     217     244 ..     201     251 .. 0.59

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 2.5e-06
                 EEEEEETTEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Prefoldin  61 vlvdlGagyyveksleeAiellkkkleelekqlekleeeleklkdqittleanlaq 116
                 ++v + +++ +e +l eA+  l+++++e++ ++e++e+  ++l++++++++ +  +
  EEA19479.1 107 LIVGHNENVELEATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTK 162
                 789999********************************************987665 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.086
                 HHHHHHHHHHHHHHHHHHHH CS
   Prefoldin   3 eeleslqaelaqlkeaieel 22 
                 ee++ l++++a+lk+++  +
  EEA19479.1 168 EEIAQLEQTIASLKQSQAAY 187
                 34455555555555555544 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.26
                 HHHHHHHHHHHHHHHHHHHHHHTT.-TT-EEEEEEETTEEEEEE--STTEEEEEEETTEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Prefoldin  11 elaqlkeaieelektletlktlkkedegkevlvplgaglyvkaevkdtdkvlvdlGagyyveksleeAiellkkkleelekqlekleeeleklkdqitt 109
                 e                                                                          l+ +++q+ +l++ l  ++++++ 
  EEA19479.1 217 E--------------------------------------------------------------------------LAAIDRQIASLQNTLPRKTREAEA 241
                 3..........................................................................333455666666666666666665 PP

                 HHH CS
   Prefoldin 110 lea 112
                 +e+
  EEA19479.1 242 MER 244
                 555 PP

>> DUF948  Bacterial protein of unknown function (DUF948)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   2.6   6.2e-06    0.0035      23      88 ..     116     181 ..     113     182 .. 0.96
   2 ?   -0.6   0.0         3   1.7e+03      29      50 ..     219     240 ..     204     261 .. 0.55

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 6.2e-06
      DUF948  23 klkktldeaaatieelekqvdpilkevedllakvnelledvneklekvdplteavadlgesvseln 88 
                 +l+ tl ea++++++ +++v+ +++e+e++ +   +  ++++ ++ k+ +l e++a+l +++++l+
  EEA19479.1 116 ELEATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTKLSELPEEIAQLEQTIASLK 181
                 7899***********************************************************997 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 3
      DUF948  29 deaaatieelekqvdpilkeve 50 
                  ++ ++i++l++ +   ++e+e
  EEA19479.1 219 AAIDRQIASLQNTLPRKTREAE 240
                 3333344444443333333333 PP

>> TPR_MLP1_2  TPR/MLP1/MLP2-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   8.2   4.3e-05     0.024       9      84 ..     113     188 ..     110     200 .. 0.90
   2 ?    1.9   1.9      0.39   2.2e+02      60      87 ..     219     246 ..     203     278 .. 0.49

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 4.3e-05
  TPR_MLP1_2   9 eikslkeekeeaeaklqklqedlekqaeiakeaqqkYerelvkhaedvkelqalreelnelkaeiaelkaeaesak 84 
                 e  +l++  +ea+++lq+ +++++ + e++++  ++ +r  ++   ++++l++l ee+++l+++ia+lk++  +  
  EEA19479.1 113 ENVELEATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTKLSELPEEIAQLEQTIASLKQSQAAYA 188
                 677899999***********************************************************98876655 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.39
  TPR_MLP1_2  60 qalreelnelkaeiaelkaeaesakael 87 
                 +a+  ++++l++++   + eae+ + el
  EEA19479.1 219 AAIDRQIASLQNTLPRKTREAEAMEREL 246
                 3333333333333333333333333333 PP

>> BLOC1_2  Biogenesis of lysosome-related organelles complex-1 subunit 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   5.7   5.3e-05      0.03      24      84 ..     120     180 ..     112     186 .. 0.91
   2 ?    0.8   0.1       1.1     6e+02      64      80 ..     215     231 ..     203     253 .. 0.67
   3 ?    0.0   0.1       1.9   1.1e+03      67      80 ..     218     231 ..     214     295 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 5.3e-05
     BLOC1_2  24 lLeklNeaasekykklkdvaaslekkleklnekyeelqpylqqidqiekqvteLeeavseL 84 
                 +L +  ++ +++ ++++ +++++ek+  +l ++y+++q   +++ ++ +++++Le++++ L
  EEA19479.1 120 TLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTKLSELPEEIAQLEQTIASL 180
                 57777888899999********************************************988 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 1.1
     BLOC1_2  64 lqqidqiekqvteLeea 80 
                   ++ +i++q+++L+++
  EEA19479.1 215 EAELAAIDRQIASLQNT 231
                 44556666666666554 PP

  == domain 3  score: 0.0 bits;  conditional E-value: 1.9
     BLOC1_2  67 idqiekqvteLeea 80 
                 + +i++q+++L+++
  EEA19479.1 218 LAAIDRQIASLQNT 231
                 44555555555544 PP

>> SlyX  SlyX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   3.2     0.058        32      21      52 ..     116     147 ..     113     159 .. 0.85
   2 ?    4.9   0.3      0.07        39       4      26 ..     162     184 ..     159     193 .. 0.67
   3 ?   12.6   1.9   0.00028      0.16       9      56 ..     215     262 ..     209     272 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.058
                 HHHHHHHHHHHHHHHHHHHHHHHHHT-XXXXX CS
        SlyX  21 eLndvvaeqqqqidrlqrqlrllaerlkelee 52 
                 eL +++ae  qq+++ + ++r ++e++++   
  EEA19479.1 116 ELEATLAEAKQQLQQRKDEVRVMVEEMEKTGR 147
                 79999*******************99976554 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.07
                 HHHHHHHHHHHHHHHHHHHHHHH CS
        SlyX   4 rleeLEiklafqedtieeLndvv 26 
                 +l eL +++a +e+ti +L +  
  EEA19479.1 162 KLSELPEEIAQLEQTIASLKQSQ 184
                 56677777777777777776654 PP

  == domain 3  score: 12.6 bits;  conditional E-value: 0.00028
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT-XXXXXXXXX CS
        SlyX   9 EiklafqedtieeLndvvaeqqqqidrlqrqlrllaerlkeleessga 56 
                 E +la  +++i +L++++ +  ++ ++++r+l  l++r +++  ++++
  EEA19479.1 215 EAELAAIDRQIASLQNTLPRKTREAEAMERELGVLERRKSDAIGQARE 262
                 889*********************************999777666554 PP

>> OmpH  Outer membrane protein (OmpH-like)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   7.0     0.001      0.56      23      79 ..     116     183 ..     109     197 .. 0.52
   2 ?    7.6   1.0    0.0082       4.6      29      84 ..     212     269 ..     202     293 .. 0.59

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.001
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTS.............-HHHHHHHHHHHHHHHHHHHHH CS
        OmpH  23 qlekkfkklqaeleakekelqklqeelqkkakkl.e...........keekeqelqkkeqelqqkqqqk 79 
                 +le++ ++ +++l+++++e++ ++ee++k  ++l               e  +e++++eq +   ++q 
  EEA19479.1 116 ELEATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLaRryqniqiettkLSELPEEIAQLEQTIAS-LKQS 183
                 6777777777777777777777777777555553223222222111122233334444444444.2222 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0082
                 HHHHHHHHHHHHHHHHHHHHHHHHTTTS.-HHHHHH....HHHHHHHHHHHHHHHHHHHH CS
        OmpH  29 kklqaeleakekelqklqeelqkkakklekeekeqe....lqkkeqelqqkqqqkaqelq 84 
                 ++++ael+a  +++ +lq++l +k+++   e+ e+e     ++k +++ q++++++++l+
  EEA19479.1 212 AEREAELAAIDRQIASLQNTLPRKTRE--AEAMERElgvlERRKSDAIGQAREAERKKLE 269
                 566777777777777777777655554..4555555555333333444443333335554 PP

>> Kre28  Spindle pole body component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   6.4    0.0011      0.63      71     211 ..      67     201 ..      54     246 .. 0.72

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0011
       Kre28  71 pkllsekikelnkLvelLklthleqEtLDnFlrYTisstdllqleSesDpkyvsleeeVseLedetltekeseieqikgeIkekgkelaekqdqinely 169
                 p  l++   ++++L   L+  +leq t   Flr  + +  +l +  +     v+le    e ++ +l+++++e+  + +e++++g++la + ++i+ + 
  EEA19479.1  67 PASLEADLTHYKELFSKLRFSYLEQVTKEKFLRGIVGDP-PLIVGHN---ENVELEATLAEAKQ-QLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIET 160
                 778999999************************766655.5555443...45888888888776.5788999999999999999999999999998877 PP

       Kre28 170 LettneideCwelLnEleelrdrrnkvekqtseekdteddlv 211
                    +   +e  +l + + +l+ + +     +s+ ++t++ + 
  EEA19479.1 161 TKLSELPEEIAQLEQTIASLK-QSQAAYAAASDPHNTSSSPN 201
                 777777777777666666666.55555556666666655554 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   8.3   0.00065      0.37     198     263 ..     118     183 ..     109     191 .. 0.66
   2 ?    6.5   2.2    0.0061       3.4     202     252 ..     212     262 ..     190     281 .. 0.50

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00065
        Spc7 198 keeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaervleeckgw 263
                 ++ L+e++++l++ k e++   +e+++  ++l++  ++i+  +++ sel eeia+ e+++   k++
  EEA19479.1 118 EATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTKLSELPEEIAQLEQTIASLKQS 183
                 456677777777777777777777777777777777777777777777777777777766665554 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0061
        Spc7 202 eelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiae 252
                 +e   ela+++ +i+++++ l +++++ e+ e ++  l+ +ks++  + +e
  EEA19479.1 212 AEREAELAAIDRQIASLQNTLPRKTREAEAMERELGVLERRKSDAIGQARE 262
                 222333344444444444444444444444444444444444444444444 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3  12.0    0.0012      0.65     130     237 ..     131     264 ..      86     281 .. 0.65

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.0012
     DUF4407 130 a...........................ltaelaeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaakekkaqldaaqaelae 201
                                              t++l+el ++ia+l+++i+++++  +a++a+a +  ++t+++     +   +   e++a+l+a+++++a+
  EEA19479.1 131 RkdevrvmveemektgrdlarryqniqiETTKLSELPEEIAQLEQTIASLKQS-QAAYAAASDP-HNTSSSPNLSLPATLKLLAEREAELAAIDRQIAS 227
                 12222233344466666666666666777777777777777777777777654.3344444433.3344333334777888888888888888888888 PP

     DUF4407 202 lkakld.atarlaalraelaeleaerakeraasqaaa 237
                 l+++l  +t + +a ++el  le+++++++ + ++a+
  EEA19479.1 228 LQNTLPrKTREAEAMERELGVLERRKSDAIGQAREAE 264
                 8888776666666667777777777666666555544 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   4.7   0.00082      0.46      53     123 ..     117     183 ..     111     185 .. 0.70
   2 ?   -0.3   0.0       1.8     1e+03      65      92 ..     222     249 ..     205     270 .. 0.57

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00082
     DUF1664  53 vseslaatkrhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeaveglesklerieek 123
                 + ++la++k++L++r d+v   ++e++++ +++++  ++++ ++++    ++++ e + +le++++++++ 
  EEA19479.1 117 LEATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTK----LSELPEEIAQLEQTIASLKQS 183
                 56899****************9999998888877776666654433....344445555555555555544 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 1.8
     DUF1664  65 ssridrvdkkldeqkeiskeikeevtev 92 
                  ++i++++++l   ++ ++++++e+  +
  EEA19479.1 222 DRQIASLQNTLPRKTREAEAMERELGVL 249
                 2334444444444444444444444333 PP

>> TPD52  Tumour protein D52 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   1.4     0.019        10      16      52 ..     152     186 ..     130     195 .. 0.71
   2 ?    6.9   0.2    0.0081       4.5      32      67 ..     214     249 ..     190     253 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.019
       TPD52  16 svsaseptlteeereeLkseLakleeeivtLrqvLaa 52 
                    ++++++  ++ +eL +e+a+le+ i++L+q  aa
  EEA19479.1 152 R--YQNIQIETTKLSELPEEIAQLEQTIASLKQSQAA 186
                 3..3344577778889999999999999999997665 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0081
       TPD52  32 LkseLakleeeivtLrqvLaakekhlaelkrklGlt 67 
                  ++eLa ++ +i++L+++L  k +++  + r lG+ 
  EEA19479.1 214 REAELAAIDRQIASLQNTLPRKTREAEAMERELGVL 249
                 4689******************************86 PP

>> DUF3552  Domain of unknown function (DUF3552)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   7.5    0.0063       3.5      82     151 ..     116     185 ..     110     190 .. 0.48
   2 ?    7.5   3.5    0.0044       2.5      74     135 ..     212     270 ..     209     283 .. 0.77

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0063
     DUF3552  82 rlekRllqkeetLdrkeeslekkeesleekekelkqkeqsleekeeeleelveeqrqeLerisgLtkeeA 151
                 +le  l + +++L++++++++   e++e++ ++l+++ q+++ + ++l+el ee  q  + i+ L++ +A
  EEA19479.1 116 ELEATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTKLSELPEEIAQLEQTIASLKQSQA 185
                 3444444444444444444444444444444444444444555555555544444444444555555555 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0044
     DUF3552  74 kerrnelqrlekRllqkeetLdrkeeslekkeesleekekelkqkeqsleekeeeleelvee 135
                  er++el+++++++ + ++tL rk+++ e  e++l   e++   k++ + + +e   + +e 
  EEA19479.1 212 AEREAELAAIDRQIASLQNTLPRKTREAEAMERELGVLERR---KSDAIGQAREAERKKLEG 270
                 69****************************99999988887...555555544444444444 PP

>> DUF724  Protein of unknown function (DUF724)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   4.0     0.024        13      89     149 ..     127     187 ..     124     199 .. 0.74
   2 ?    7.5   0.9     0.006       3.4     127     179 ..     213     265 ..     207     270 .. 0.87

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.024
      DUF724  89 alqsrlnkLlslkdeqtklleerkklekkieeeesekrkleeeidelekkilelerqlall 149
                 +lq+r +++  + +e +k+ + + +  ++i+ e+++ ++l eei++le++i+ l++ +a+ 
  EEA19479.1 127 QLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTKLSELPEEIAQLEQTIASLKQSQAAY 187
                 5666666777777777777777777788888888888888888888888888888877754 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.006
      DUF724 127 kleeeidelekkilelerqlallkekkeaadkeiarlkseaekleeeledveq 179
                 + e+e++ ++++i+ l++ l ++ ++ ea+++e+  l+  ++++  + +++e+
  EEA19479.1 213 EREAELAAIDRQIASLQNTLPRKTREAEAMERELGVLERRKSDAIGQAREAER 265
                 568999***************999*************9999987766666665 PP

>> zf-C4H2  Zinc finger-containing protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   6.7    0.0035       1.9      62     153 ..     115     209 ..     107     244 .. 0.64

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0035
     zf-C4H2  62 nalEsvikeaeeekekslekakklyeeykklkeevnelrselglekledleeeeeel.lkeeifekqklkaaavelkkesstapappa..pptsl 153
                  +lE ++ ea+++ ++++++++ ++ee++k  +++ +  +++ +e+ +  e +ee + l+++i + ++++aa ++++++++t+++p    p t +
  EEA19479.1 115 VELEATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTKLSELPEEIAqLEQTIASLKQSQAAYAAASDPHNTSSSPNLslPATLK 209
                 579***************************99999999888777755444444443304666644444444444444444444444444343333 PP

>> Lzipper-MIP1  Leucine-zipper of ternary complex factor MIP1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   9.3    0.0022       1.2       3      72 ..     111     182 ..     109     185 .. 0.74
   2 ?    4.1   0.1       0.1        57      40      81 ..     194     232 ..     183     235 .. 0.63

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0022
  Lzipper-MIP1   3 sekrssLeqeveqLqerLqeeeklrraLekalssss.dgsllslstllp.kkakellkeiallEeevvkLEq 72 
                   ++++++Le   ++ +++Lq+ ++  r++ + ++++  d +   ++  +   k  el +eia+lE++++ L+q
    EEA19479.1 111 HNENVELEATLAEAKQQLQQRKDEVRVMVEEMEKTGrDLARRYQNIQIEtTKLSELPEEIAQLEQTIASLKQ 182
                   78999**************998766666666633331333333333344489******************98 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.1
  Lzipper-MIP1  40 gsllslstllpkkakellkeiallEeevvkLEqkllsLyrkl 81 
                   ++++s+++l+ +++   lk +a  E+e +   +++ sL+ +l
    EEA19479.1 194 HNTSSSPNLSLPAT---LKLLAEREAELAAIDRQIASLQNTL 232
                   33334444333444...55555578999********999876 PP

>> BST2  Bone marrow stromal antigen 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   7.9    0.0024       1.3      16      85 ..     111     180 ..     110     187 .. 0.93
   2 ?    2.3   1.9      0.46   2.6e+02      15      72 ..     193     250 ..     182     269 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0024
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        BST2  16 rnvtrlLerqLtqaqeslreaeaqaatcnqtvvtLkasLekekaqsqkqqakvqelqgeikkLnqkLqda 85 
                 +n +  Le+ L++a+++l++ ++++    + +++   +L +   + q + +k+ el +ei++L+q +   
  EEA19479.1 111 HNENVELEATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTKLSELPEEIAQLEQTIASL 180
                 788999***********************************************************98765 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.46
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        BST2  15 crnvtrlLerqLtqaqeslreaeaqaatcnqtvvtLkasLekekaqsqkqqakvqelq 72 
                  +n++   +  L  + + l+e ea+ a+ ++ + +L++ L +++ +++ +++++  l+
  EEA19479.1 193 PHNTSSSPNLSLPATLKLLAEREAELAAIDRQIASLQNTLPRKTREAEAMERELGVLE 250
                 5666666677788888899999*****************9999888777766665555 PP

>> ADIP  Afadin- and alpha -actinin-Binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   2.2      0.32   1.8e+02      94     121 ..     111     138 ..     107     145 .. 0.81
   2 ?    6.2   1.4     0.018        10      64     105 ..     144     185 ..     138     192 .. 0.74
   3 ?    8.1   0.8    0.0046       2.6      59     120 ..     215     277 ..     208     288 .. 0.72

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.32
        ADIP  94 qakerqlekklktleqklknekeelqrl 121
                 +++  +le++l++++q+l++ k+e++ +
  EEA19479.1 111 HNENVELEATLAEAKQQLQQRKDEVRVM 138
                 5677789999999999999999999755 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.018
        ADIP  64 kleaeierlqskierlktqleqlerelalvqakerqlekklk 105
                 k   +++r  ++i+  +t+l++l  e+a+++++ ++l+++++
  EEA19479.1 144 KTGRDLARRYQNIQIETTKLSELPEEIAQLEQTIASLKQSQA 185
                 555677777888888888888888888888888888887765 PP

  == domain 3  score: 8.1 bits;  conditional E-value: 0.0046
        ADIP  59 netirkleaeierlqskierlktqleqlerelalvqakerqlekklkt.leqklknekeelqr 120
                 ++++  ++  i++lq++  r +++ e+ erel ++++++ ++  + ++ + +kl +e++ l+ 
  EEA19479.1 215 EAELAAIDRQIASLQNTLPRKTREAEAMERELGVLERRKSDAIGQAREaERKKLEGESDGLEE 277
                 667778888999999999999999999999999666666555555555045567777776655 PP

>> ABC_tran_CTD  ABC transporter C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   2.2      0.76   4.3e+02      19      59 ..     116     151 ..     112     155 .. 0.61
   2 ?   13.1   6.6   0.00016     0.087       8      53 ..     161     221 ..     157     230 .. 0.73
   3 ?    2.7   4.1      0.28   1.5e+02      17      60 ..     211     249 ..     202     252 .. 0.69
   4 ?    1.9   1.1      0.48   2.7e+02       7      26 ..     236     255 ..     233     281 .. 0.79

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.76
  ABC_tran_CTD  19 aLEeeiaeleaeladpelysdpeklaelsaeleeleaeLee 59 
                   +LE+ +ae  ++l++       +++    +e+e+   +L++
    EEA19479.1 116 ELEATLAEAKQQLQQRK-----DEVRVMVEEMEKTGRDLAR 151
                   46666666666666543.....5566666666666666665 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 0.00016
  ABC_tran_CTD   8 releeleaeIeaLEeeiaeleaeladpelysdp.ek..............laelsaeleel 53 
                    +l el++eI++LE+ ia+l +  a+ +  sdp ++              lae  ael+++
    EEA19479.1 161 TKLSELPEEIAQLEQTIASLKQSQAAYAAASDPhNTssspnlslpatlklLAEREAELAAI 221
                   6799******************999999889996445677777555555555555555555 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.28
  ABC_tran_CTD  17 IeaLEeeiaeleaeladpelysdpeklaelsaeleeleaeLeel 60 
                   +++ E+e+a+++ ++a+ +     ++l + ++e e+ e eL  l
    EEA19479.1 211 LAEREAELAAIDRQIASLQ-----NTLPRKTREAEAMERELGVL 249
                   5667788888888888655.....56777777777777777655 PP

  == domain 4  score: 1.9 bits;  conditional E-value: 0.48
  ABC_tran_CTD   7 qreleeleaeIeaLEeeiae 26 
                    re e++e+e+  LE ++++
    EEA19479.1 236 TREAEAMERELGVLERRKSD 255
                   68889999999998888765 PP

>> DUF1043  Protein of unknown function (DUF1043)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   8.7     0.014       7.6      25      98 ..     113     184 ..     109     275 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.014
     DUF1043  25 kqkklekelekakaeleeqkqeledHfaqsaelLetlaedyqkLyqhlaksseeLlpeleeqelfqqkkleekk 98 
                 ++ +le++l +ak++l++ k+e+    ++  +  ++la++yq+++   +k se  lpe+  q  +  ++l++++
  EEA19479.1 113 ENVELEATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTKLSE--LPEEIAQLEQTIASLKQSQ 184
                 56789999999999999999999988888888888888888877655444433..3422222222223333333 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   4.8      0.18     1e+02      11      55 ..     126     169 ..     110     202 .. 0.53
   2 ?    5.5   0.1     0.046        26      10      75 ..     211     280 ..     205     284 .. 0.74

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.18
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHXXX CS
        YabA  11 eeleeqleelleeleelkeelaelleenaeLeleneklrerleee 55 
                 ++l+++ +e+   +ee++++  +l  + +++++e +kl e+ e e
  EEA19479.1 126 QQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTKLSELPE-E 169
                 3344444444444455555555566666666666666665542.2 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.046
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH....XXXXXXXXXXXXXXXXXXXXXXX CS
        YabA  10 leeleeqleelleeleelkeelaelleenaeLeleneklrerl....eeeekkekekkkelsegkenLar 75 
                 l+e e +l+++ +++++l+++l + + e +++e e   l +r      +++++e++k +  s+g e++ r
  EEA19479.1 211 LAEREAELAAIDRQIASLQNTLPRKTREAEAMERELGVLERRKsdaiGQAREAERKKLEGESDGLEEMGR 280
                 566788999999***********************99998888555544445555555555555555555 PP

>> Laminin_II  Laminin Domain II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   4.3    0.0062       3.5      14      87 ..     116     189 ..     111     196 .. 0.89
   2 ?    3.3   0.3      0.14        79       6      60 ..     212     266 ..     207     277 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0062
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--TTTTTGGGHHHHHHHHHH... CS
  Laminin_II  14 evleqlaplsqnlentkeklseinrsveetnekvkdankairdArrsvkkLeklapqLldklkelkqleeasss 87 
                 e ++ la+ +q+l++ k+++  + +++e+t  ++    + i+   ++ ++L +++ qL++ + +lkq + a ++
  EEA19479.1 116 ELEATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTKLSELPEEIAQLEQTIASLKQSQAAYAA 189
                 66788999999***********99***********999****************************99887655 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.14
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Laminin_II   6 aeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankairdArrs 60 
                 ae +  ++++ +q+a l++ l++   +++ ++r++   +   +da  + r+A+r+
  EEA19479.1 212 AEREAELAAIDRQIASLQNTLPRKTREAEAMERELGVLERRKSDAIGQAREAERK 266
                 5666678889999999999999999999999999998888888888888888875 PP

>> Atg14  Vacuolar sorting 38 and autophagy-related subunit 14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7  13.4     0.048        27      56     128 ..     115     187 ..     106     280 .. 0.64

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.048
       Atg14  56 eqledkiknkkakleelksliadlrerlqelkdklsqlkkeieekkkklaklsdklkkRrsdleslqneleer 128
                  +le+ +   k++l++ k +++   e++++   +l ++ + i++   kl++l +++++  ++++sl+++ +++
  EEA19479.1 115 VELEATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTKLSELPEEIAQLEQTIASLKQSQAAY 187
                 4455555555566666666666666666666666666666666666666666666665555555555443333 PP

>> Lebercilin  Ciliary protein causing Leber congenital amaurosis disease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0  10.1    0.0038       2.1     118     185 ..     113     183 ..     111     186 .. 0.88
   2 ?    6.6   1.7      0.01       5.6     116     165 ..     216     264 ..     200     280 .. 0.72

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0038
  Lebercilin 118 ereeLqkkLeeleakleekeekikeLerkleleeksfrrql...aaekkktkeaqeevkalqeeierlkqk 185
                 e  eL+  L+e++++l++++ +++ +  ++e + +  +r++   + e+ k +e+ ee+++l+++i +lkq+
  EEA19479.1 113 ENVELEATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYqniQIETTKLSELPEEIAQLEQTIASLKQS 183
                 7789*****************************99998875111579999999**************9996 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.01
  Lebercilin 116 LaereeLqkkLeeleakleekeekikeLerkleleeksfrrqlaaekkkt 165
                   e + + +++++l+++l +k+++ + +er+l ++e+  +  + + ++ +
  EEA19479.1 216 A-ELAAIDRQIASLQNTLPRKTREAEAMERELGVLERRKSDAIGQAREAE 264
                 3.555678899999999999999999999999888887776665555443 PP

>> DUF4140  N-terminal domain of unknown function (DUF4140)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   0.6     0.049        28      65      94 ..      99     141 ..      37     145 .. 0.71
   2 ?    8.2   0.9     0.006       3.4      50      87 ..     154     190 ..     145     199 .. 0.72
   3 ?    4.4   2.6     0.093        52      63      98 .]     214     249 ..     192     277 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.049
     DUF4140  65 e.............elkalraeleeledelaaledelaaaear 94 
                               e  +l+a+l e++++l++ +de ++  ++
  EEA19479.1  99 RgivgdpplivghnENVELEATLAEAKQQLQQRKDEVRVMVEE 141
                 1555556666666668899999999999999999998887665 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.006
     DUF4140  50 ldvqvervpnreaeeeelkalraeleeledelaalede 87 
                 +++q+e++  +e +ee +++l++++ +l++ +aa+ ++
  EEA19479.1 154 QNIQIETTKLSELPEE-IAQLEQTIASLKQSQAAYAAA 190
                 5677777777777775.888888888888877777665 PP

  == domain 3  score: 4.4 bits;  conditional E-value: 0.093
     DUF4140  63 eeeelkalraeleeledelaaledelaaaearlafl 98 
                  e+el+a+++++ +l+ +l + ++e++a e +l +l
  EEA19479.1 214 REAELAAIDRQIASLQNTLPRKTREAEAMERELGVL 249
                 222588999999999999999999998888888765 PP

>> UPF0449  Uncharacterised protein family UPF0449
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   1.9    0.0023       1.3      66      97 ..     113     144 ..     110     155 .. 0.74
   2 ?   -0.7   0.1       3.6     2e+03      74      92 ..     163     177 ..     147     192 .. 0.49
   3 ?    0.3   0.2       1.8   9.9e+02      45      95 ..     196     246 ..     167     249 .. 0.66

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0023
     UPF0449  66 tylelnerLeeakeeLkqkceeLktageeLee 97 
                 +++el+  L eak++L+q+ +e +++ ee+e+
  EEA19479.1 113 ENVELEATLAEAKQQLQQRKDEVRVMVEEMEK 144
                 56777788888888888888888888777775 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 3.6
     UPF0449  74 LeeakeeLkqkceeLktag 92 
                 L+e  ee+     +L++  
  EEA19479.1 163 LSELPEEIA----QLEQTI 177
                 222222222....222222 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 1.8
     UPF0449  45 assseeedleaeveelYeqvrtylelnerLeeakeeLkqkceeLktageeL 95 
                 +sss +++l a    l e+  ++ ++++++ + +++L +k+ e +++ +eL
  EEA19479.1 196 TSSSPNLSLPATLKLLAEREAELAAIDRQIASLQNTLPRKTREAEAMEREL 246
                 333345677777777777788888888888888888888888777766665 PP

>> AAA_13  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9  11.5      0.03        17     329     468 ..     113     247 ..      70     270 .. 0.59

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.03
      AAA_13 329 eaealeeqLkglqraleaKrkepfksve.lesvkakiesikklvaeineliakhNekvanleeekeeakkklelhlveeleseldeykkkykklekaie 426
                 e  +le++L +++++l+++++e+   ve +e++  ++ +  ++++   +  ++  e +a+le+  +++k++  ++ +++        +++ ++ + ++ 
  EEA19479.1 113 ENVELEATLAEAKQQLQQRKDEVRVMVEeMEKTGRDLARRYQNIQIETTKLSELPEEIAQLEQTIASLKQSQAAYAAASD------PHNTSSSPNLSLP 205
                 55577888888888888888888776655788877775444444444444444444444444444444444444333211......1122222222333 PP

      AAA_13 427 klekelkeeeaelkkleeeikeLekqlrdekpaaeeinkeLk 468
                  + k l+e eael++++ +i+ L+++l  +++ ae +++eL 
  EEA19479.1 206 ATLKLLAEREAELAAIDRQIASLQNTLPRKTREAEAMERELG 247
                 333344444444444444444444444444444444444443 PP

>> Prefoldin_2  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   3.6     0.001      0.57      57      99 ..     118     160 ..     114     165 .. 0.91
   2 ?    1.9   0.3      0.38   2.1e+02       7      26 ..     163     182 ..     158     188 .. 0.46
   3 ?    2.0   0.2      0.35     2e+02      66      99 ..     213     246 ..     207     252 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.001
                  EE-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Prefoldin_2  57 kqdkeevkeeLeerketlekeiktlekqleklekeleelkeel 99 
                  + +++e+k++L++rk+++   ++++ek  ++l +++++++ e 
   EEA19479.1 118 EATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIET 160
                  67899*********************************99775 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.38
                  HHHHHHHHHHHHHHHHHHHH CS
  Prefoldin_2   7 fqqlqqqlqqlaqqikqlet 26 
                  +++l +++ ql+q i++l++
   EEA19479.1 163 LSELPEEIAQLEQTIASLKQ 182
                  33333333333333333333 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.35
                  HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Prefoldin_2  66 eLeerketlekeiktlekqleklekeleelkeel 99 
                  e e++++ ++ +i++l++ l ++ +e e ++ el
   EEA19479.1 213 EREAELAAIDRQIASLQNTLPRKTREAEAMEREL 246
                  5577788888888888888888888888887776 PP

>> HIP1_clath_bdg  Clathrin-binding domain of Huntingtin-interacting protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   7.2     0.021        12      31      93 ..     116     181 ..     110     191 .. 0.47
   2 ?    5.1   0.4      0.06        34      59      96 ..     216     253 ..     208     256 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.021
  HIP1_clath_bdg  31 eleeelerlkeeaerkleeqk...eelekLkreleakraelarlkssLesseqsgeqlssqlaaLq 93 
                     ele +l ++k++ +++ +e +   ee+ek  r+l+++ ++++   + L++  ++ +ql++++a+L+
      EEA19479.1 116 ELEATLAEAKQQLQQRKDEVRvmvEEMEKTGRDLARRYQNIQIETTKLSELPEEIAQLEQTIASLK 181
                     444444444444444433332111233333445555555555555555555555555555555554 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.06
  HIP1_clath_bdg  59 releakraelarlkssLesseqsgeqlssqlaaLqaEk 96 
                     +el+a   ++a+l+++L +++++ e ++ +l  L++ k
      EEA19479.1 216 AELAAIDRQIASLQNTLPRKTREAEAMERELGVLERRK 253
                     6899999999*****************99999999876 PP

>> CENP-Q  CENP-Q, a CENPA-CAD centromere complex subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   8.8      0.23   1.3e+02      32      89 ..     112     169 ..     111     200 .. 0.77
   2 ?    9.6   6.6    0.0018      0.99      25      89 ..     202     267 ..     193     280 .. 0.80

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.23
      CENP-Q  32 dekaaleaqLspelhslelLeaeiekeeralerdyeaLreLeknakaearerkeklkk 89 
                 +e+ +lea L+ ++++l++ + e++ ++++ e+  + L++  +n+++e+ +  e  ++
  EEA19479.1 112 NENVELEATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLARRYQNIQIETTKLSELPEE 169
                 68999*******************************9999999999999886553333 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.0018
      CENP-Q  25 ldfeklldekaaleaqLspelhslelLeaeiekeeralerdyeaLreLeknakaearerke.klkk 89 
                 l++ ++l+  a+ ea+L++  ++++ L++ + +  r+ e ++++L  Le+  +++  + +e ++kk
  EEA19479.1 202 LSLPATLKLLAEREAELAAIDRQIASLQNTLPRKTREAEAMERELGVLERRKSDAIGQAREaERKK 267
                 6777889999999******************99999999999999999988777776654424443 PP

>> BRE1  BRE1 E3 ubiquitin ligase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   2.0      0.16        90       6      42 ..     115     151 ..     111     159 .. 0.73
   2 ?    6.5   1.8     0.015       8.5       4      54 ..     134     184 ..     131     199 .. 0.85
   3 ?    7.1   1.1    0.0098       5.5       3      54 ..     216     267 ..     214     273 .. 0.94

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.16
        BRE1   6 vklekafeelseqlskkvkeltileekklrleaekak 42 
                 v+le+   e+++ql++ + e+  + e++ ++  + a+
  EEA19479.1 115 VELEATLAEAKQQLQQRKDEVRVMVEEMEKTGRDLAR 151
                 6778888888888888888888888887777666655 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.015
        BRE1   4 ELvklekafeelseqlskkvkeltileekklrleaekakadqkyfaamrsk 54 
                 E+  + +++e++ + l   +++++i + k++ l  e+a+ +q + +++ s 
  EEA19479.1 134 EVRVMVEEMEKTGRDLARRYQNIQIETTKLSELPEEIAQLEQTIASLKQSQ 184
                 777788999999999999999999999999999999999999999888775 PP

  == domain 3  score: 7.1 bits;  conditional E-value: 0.0098
        BRE1   3 kELvklekafeelseqlskkvkeltileekklrleaekakadqkyfaamrsk 54 
                 +EL  + +++  l+++l  k+ e +++e ++  le  k+ a  +  +a+r+k
  EEA19479.1 216 AELAAIDRQIASLQNTLPRKTREAEAMERELGVLERRKSDAIGQAREAERKK 267
                 79***********************************************987 PP

>> Cob_adeno_trans  Cobalamin adenosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   5.2     0.018        10      34     132 ..     116     214 ..     109     230 .. 0.62
   2 ?    1.0   0.3      0.73   4.1e+02      53      93 ..     214     251 ..     202     290 .. 0.55

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.018
                      HHHHHHHHHHHHCTTTTHHHHHHHHHHHHHHHHHHHHHHT......-BTCCG-S--HHHHHHHHHHHHHHHHHS--EESEEES-SSHHHHHHHH CS
  Cob_adeno_trans  34 elnsaiglarallaeeeeelkeaLeeiqneLfdlgaelatp.....ekkkekkkiteeeveelekeideleaelpplksfilpggspaaaalhv 122
                      el++++  a+++l++     k++++ + +e+ + g +la        ++++ +++  ee+++le+ i +l+++    +    p+++ ++ +l++
       EEA19479.1 116 ELEATLAEAKQQLQQR----KDEVRVMVEEMEKTGRDLARRyqniqIETTKLSELP-EEIAQLEQTIASLKQSQAAYAAASDPHNTSSSPNLSL 204
                      7788888888666555....555555556666666666644432221222233334.4488888888888877776666666666666666666 PP

                      HHHHHHHHHH CS
  Cob_adeno_trans 123 aRtvcRraER 132
                        t+   aER
       EEA19479.1 205 PATLKLLAER 214
                      6666555555 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.73
                      HHHHHHHHHHHHHHHHHHHHT.-BTCCG-S--HHHHHHHHH CS
  Cob_adeno_trans  53 lkeaLeeiqneLfdlgaelatpekkkekkkiteeeveelek 93 
                       +++L+ i +++ +l+++l  p+k++e+++++ e +  le+
       EEA19479.1 214 REAELAAIDRQIASLQNTL--PRKTREAEAMERE-LGVLER 251
                      3445555555555555555..2333333333322.433443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (297 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1635  (0.091193); expected 358.6 (0.02)
Passed bias filter:                      762  (0.042501); expected 358.6 (0.02)
Passed Vit filter:                       124  (0.00691617); expected 17.9 (0.001)
Passed Fwd filter:                        55  (0.00306766); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              32  [number of targets reported over threshold]
# CPU time: 0.90u 0.35s 00:00:01.25 Elapsed: 00:00:00.53
# Mc/sec: 1697.90
//
Query:       EEA19480.1  [L=191]
Description: 40S ribosomal protein S9 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-12   47.5   0.8    1.1e-12   47.5   0.8    2.4  3  S4            S4 domain
    2.7e-06   28.2   0.2    5.4e-06   27.2   0.2    1.6  1  Ribosomal_S4  Ribosomal protein S4/S9 N-terminal domain


Domain annotation for each model (and alignments):
>> S4  S4 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.1      0.44   3.9e+03      16      22 ..      53      59 ..      45      60 .. 0.69
   2 ?   -2.0   0.1      0.35   3.1e+03       1       8 [.      91      98 ..      91     101 .. 0.82
   3 !   47.5   0.8   1.2e-16   1.1e-12       1      44 [.     107     150 ..     107     153 .. 0.96

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.44
                HHHHHHH CS
          S4 16 rreArql 22
                rr Ar+l
  EEA19480.1 53 RRAAREL 59
                8888887 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.35
                EEHHHHHH CS
          S4  1 rRLdkvla 8 
                + Ld vla
  EEA19480.1 91 MKLDYVLA 98
                78****98 PP

  == domain 3  score: 47.5 bits;  conditional E-value: 1.2e-16
                 EEHHHHHHHTTSSSSHHHHHHHHHTTTEEETTEEE--TT-EE-T CS
          S4   1 rRLdkvlarlglassrreArqlIehGrVlVNGkvvkdpsyrVkp 44 
                 rRL++ +++lgla+s+ +Ar lI++++++V +++v+ psy+V+ 
  EEA19480.1 107 RRLQTCVYKLGLAKSIHHARVLIRQRHIRVGKQIVNVPSYMVRL 150
                 8*****************************************85 PP

>> Ribosomal_S4  Ribosomal protein S4/S9 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.2   0.2     6e-10   5.4e-06      11      81 ..      16      62 ..       4     106 .. 0.84

  Alignments for each domain:
  == domain 1  score: 27.2 bits;  conditional E-value: 6e-10
                  CHCTS-STSSSS-S-SSTTTTS-----CHCH.HHHHHHHHHHHHT-S.HHHHHHHHHHHHHCCSHHHHHHHHH CS
  Ribosomal_S4 11 RrvgfklflkgreyppGqhgkrrkklseYgk.qlrekqklkrrYgll.ekqfrryfkearrirGktgenLlql 81
                  R                          +Y++ +l+ + k  ++Ygl+ +++++r++  +++ir + +++Ll+l
    EEA19480.1 16 R-------------------------RPYESaRLDSELKTVGEYGLRnKREVWRVQLTLSKIR-RAARELLTL 62
                  3.........................49***********************************.*******94 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (191 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       440  (0.0245412); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1263.87
//
Query:       EEA19481.1  [L=160]
Description: 60S ribosomal protein L21, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.7e-44  149.8   2.4    2.8e-44  149.1   2.4    1.3  1  Ribosomal_L21e  Ribosomal protein L21e


Domain annotation for each model (and alignments):
>> Ribosomal_L21e  Ribosomal protein L21e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  149.1   2.4   1.5e-48   2.8e-44       1     101 []       1     101 [.       1     101 [. 0.99

  Alignments for each domain:
  == domain 1  score: 149.1 bits;  conditional E-value: 1.5e-48
                     X--S-STTTT-TTTTS--GGG-SS--SHHHH----TT-EEEE---TT--SS---GGGTT-EEEE..EEEETTEEEEEEEETTE..EEEEEE-GGG CS
  Ribosomal_L21e   1 mknskglrrgtrklfskkfrkkgvpplstylreykkGdkVdikidpsvqkgmphkryhGktgrvynvtkravgvivnkkvggkileKriivrieh 95 
                     m +s glr+gtr++fs++f+k+g + l tyl+ey++Gd+Vd+k++++vqkg p+k+yhGktg+vynvtk+avgvi++k+vg+++leKr++vr+eh
      EEA19481.1   1 MGHSGGLRAGTRYAFSRDFKKRGAIALGTYLKEYRVGDIVDVKCNGAVQKGLPYKYYHGKTGVVYNVTKSAVGVIIYKRVGNRYLEKRLNVRVEH 95 
                     89********************************************************************************************* PP

                     EEE--. CS
  Ribosomal_L21e  96 lkksks 101
                     + +s+s
      EEA19481.1  96 VAHSRS 101
                     ***985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (160 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       953  (0.0531541); expected 358.6 (0.02)
Passed bias filter:                      571  (0.0318478); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 1092.03
//
Query:       EEA19482.1  [L=383]
Description: mitochondrial carrier protein (Rim2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    8.8e-74  243.5   1.9    5.5e-24   83.9   0.0    3.1  3  Mito_carr  Mitochondrial carrier protein


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.9   0.0   3.1e-28   5.5e-24       4      96 ..      45     160 ..      42     161 .. 0.85
   2 !   83.5   0.0   4.3e-28   7.6e-24       7      95 ..     173     264 ..     168     266 .. 0.90
   3 !   74.3   0.3     3e-25   5.5e-21       6      95 ..     287     381 ..     283     383 .] 0.86

  Alignments for each domain:
  == domain 1  score: 83.9 bits;  conditional E-value: 3.1e-28
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH...CCCSSTTTSCSS.......................HHHHHHHHHHHHHHHGGGTTHHHHHHHHH CS
   Mito_carr   4 svlkellaGglagavatlvttPldvvKtrlqt...qkksskksksaa.......................ildvlkkiykeeGlrglyrGllpnllrva 76 
                 ++l++++aGg++g++a+++t Pldv+Ktrlq+   q   ++ +  +a                       ++++l++iy +eG r+l++Gl+pnl++v+
  EEA19482.1  45 KPLAHFIAGGIGGMTAATLTSPLDVLKTRLQSdfyQ---TQLQALRAshpvrpapffislprsalvhfkeTFQILHSIYSHEGPRALFKGLGPNLIGVV 140
                 7899****************************6652...3333333334577778888888888888888***************************** PP

                 HHHHHHHHHHHHHHHHHCTT CS
   Mito_carr  77 pasalkfvlyetlkrlllkk 96 
                 pa+a++f +y   kr+l ++
  EEA19482.1 141 PARAINFYVYGNGKRILSNY 160
                 ***************99875 PP

  == domain 2  score: 83.5 bits;  conditional E-value: 4.3e-28
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSS....HHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCT CS
   Mito_carr   7 kellaGglagavatlvttPldvvKtrlqtqkksskksksaa....ildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlllk 95 
                  +l+a+++ag++++++t+P++++Ktrlq++k+++++ k ++     +d++k+++++eG+rgly+Gl+++ l+v+ +sa ++vlye++k +l +
  EEA19482.1 173 IHLAAAAIAGIATGTATNPIWLIKTRLQLDKSNAESGKGGRqyknSWDCIKQTVRHEGIRGLYKGLSASYLGVT-ESATQWVLYEQMKMFLAR 264
                 5899*************************9999777665556777****************************9.*************99875 PP

  == domain 3  score: 74.3 bits;  conditional E-value: 3e-25
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH......CCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCT CS
   Mito_carr   6 lkellaGglagavatlvttPldvvKtrlqt......qkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlllk 95 
                   +l+a+g+a+++a++vt+P +vv+trl        ++++ +  k++++++++k + keeGl+gly Gl+p llrv+p++a++f++ye++ rl+ +
  EEA19482.1 287 GGRLVAAGAAKLFAAVVTYPHEVVRTRLRQapvvpvAGGKMQV-KYTGLIQCFKVVAKEEGLAGLYGGLTPHLLRVVPSAAIMFGMYEVILRLFGT 381
                 6789************************995666553333333.3445********************************************9965 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (383 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       346  (0.0192983); expected 358.6 (0.02)
Passed bias filter:                      291  (0.0162307); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.24s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2756.98
//
Query:       EEA19483.1  [L=77]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (77 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       573  (0.0319594); expected 358.6 (0.02)
Passed bias filter:                      201  (0.0112109); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.33u 0.30s 00:00:00.63 Elapsed: 00:00:00.42
# Mc/sec: 550.00
//
Query:       EEA19484.1  [L=403]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (403 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       807  (0.0450109); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2883.00
//
Query:       EEA19485.1  [L=522]
Description: GABA permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.1e-60  202.8  53.8      1e-59  202.5  53.8    1.0  1  AA_permease_2  Amino acid permease
    2.5e-28   98.9  46.4    3.4e-28   98.5  46.4    1.0  1  AA_permease    Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  202.5  53.8   1.2e-63     1e-59       4     423 ..      52     493 ..      49     497 .. 0.84

  Alignments for each domain:
  == domain 1  score: 202.5 bits;  conditional E-value: 1.2e-63
  AA_permease_2   4 lsafalvigsvigsgifvkn...laasggpalilwvwiavligslavllvyaElssalprsgGiyvytkaaf....gkkvaflsawfnwfayvpvl 92 
                    +s +++ +++++   ++ +    +++ gg+a ++w+ ++v +g+l v++ +aE++s+ p+sgG+y++++++     +k++ ++++w+ + ++  ++
     EEA19485.1  52 ISILGFGCTLIATWEVVLTLltyGLTDGGTAGLIWGYVIVCVGFLLVFASLAEMASMAPTSGGQYHWVSEFApkscQKFLSYVTGWLCATGWQCAI 147
                    555555555553333322223334667********************************************6555589**********99999999 PP

  AA_permease_2  93 asilsvaasyllnal...gpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfsslstetdtffpn 185
                    +si+ +a+  +++++   +++++ ++w+  l++iai+++ +++n +  k + ++   + il+i+++  ++ii++l++  ++ +  +   t   +++
     EEA19485.1 148 VSIAFLAGTIIQGLIvlnDETYVFQRWHGTLLVIAITAFSIFFNTFLAKRLPMVEALILILHIVGL--FAIIIPLWVMAPRASAKS-VFTQFDNNG 240
                    9999888888866652225677778**************************************877..667778888888777644.223345566 PP

  AA_permease_2 186 gwpg....vllgllivlwsfdGfesaanvseevkk..kdvpkaifigllivlvlyllvniaflgvvpd.deianlsnlgsv.aalffeavggkvva 273
                    gw++    +l+g+++++ s++G+++aa++see+++   ++pka+++++++ +vl++++ +++ + ++d d+i   s++g++ +++ff+ +g+ +++
     EEA19485.1 241 GWSSlgtsTLVGFSGTITSMIGYDCAAHMSEEIRNagETLPKAMMSAVVVNAVLGFVMLVTICFTLGDvDSIL-ASPTGYPfIQVFFNSTGSYAGT 335
                    888533436*************************98669*****************************55554.345455427********99*** PP

  AA_permease_2 274 iivvilialsllgaintavigssrvlealardgvlP..rffakvn.kfgspiraiiltaivslillllfllassaaynfllsvsslgliisyllli 366
                     ++ ++++l l  + +t v+++sr+l+++ard++ P  +ff++vn  +++p++++ +++ ++ +l+ l+ ++s+aa+++++s++  +l++sy++ i
     EEA19485.1 336 NVMTAILILTLTASTITEVATASRQLWSFARDNGVPfgEFFSHVNpGWNIPLNSVLVSLAITALLS-LINIGSTAALTAIVSLTITSLMSSYIISI 430
                    *********************************************88***************6665.6667789********************** PP

  AA_permease_2 367 igalilrkkrphlkr......pgkilvaiigalfllfllvalffppkgpatqssliytiiltv 423
                     ++l+ r++ + l++      ++ + ++i ++ +l+ ++v++ffp+   +t s++++++++++
     EEA19485.1 431 SCLLLKRIRGEPLPEhrwslgKWGMAINIAALAYLCPVFVFAFFPLTSTVTVSTMNWSVVMYL 493
                    *********99885555777755688********************************55443 PP

>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.5  46.4   3.8e-32   3.4e-28      17     466 ..      70     507 ..      57     515 .. 0.77

  Alignments for each domain:
  == domain 1  score: 98.5 bits;  conditional E-value: 3.8e-32
  AA_permease  17 vglgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrf....lgpelGfviGlnylfswitvlaleltaasiliqfwelvtdl 110
                  + l + l  +G +g++ +y++++v ++lv  sl+e+a++ p sgg y+++s+f      + l++v+G++    w  ++    + a+ +iq +  +  +
   EEA19485.1  70 TLLTYGLTDGGTAGLIWGYVIVCVGFLLVFASLAEMASMAPTSGGQYHWVSEFapksCQKFLSYVTGWLCATGWQCAIVSIAFLAGTIIQGL--IVLN 165
                  557789999***************************************99876111156678*******55555555555555567777766..4444 PP

  AA_permease 111 pkawvt....gavflvvlliinlvgvkvyge.aefilalikiiaiiafiivgiillaggkpnkga..gfrflgdngsifknnlppgfakeeegafknf 201
                   +++v+    g+++++++++++++ + + ++   ++ ali+i+ i++++ +  i+l+  +p + a   f+ + +ng+    + + g         ++ 
   EEA19485.1 166 DETYVFqrwhGTLLVIAITAFSIFFNTFLAKrLPMVEALILILHIVGLFAII-IPLWVMAPRASAksVFTQFDNNGG----WSSLG---------TST 249
                  4344556678888888888888777776665145556777777777777776.344444444443458999999999....77777.........789 PP

  AA_permease 202 isvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasaaspfvifikesgvsvlaplinavilta 299
                  +++f+  + ++ G+   a +++E+++  +++Pka++++v+  +++   +l++i +++++ d  l   s ++++ + +f++++g+ +  ++++a+++++
   EEA19485.1 250 LVGFSGTITSMIGYDCAAHMSEEIRNAGETLPKAMMSAVVVNAVLGFVMLVTICFTLGDVDSILA--SPTGYPFIQVFFNSTGSYAGTNVMTAILILT 345
                  ********************************************999999999999988884444..577899************************* PP

  AA_permease 300 alssansslysasRvlyslakdglaP...kvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliilsylrfRkal 394
                  ++ s +  +++asR+l+s+a+d+  P   ++  +   ++ Pl+++l+s++i +l+ l++  ++a   + + +++++  + ++ ++++i ++l      
   EEA19485.1 346 LTASTITEVATASRQLWSFARDNGVPfgeFFSHVNPGWNIPLNSVLVSLAITALLSLINIGSTA---ALTAIVSLTITSLMSSYIISISCLL------ 434
                  ****************************777777789*********************999999...7777888888888888888888887...... PP

  AA_permease 395 kyqgrsieelgfkaal.lplgv...ilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfliilvgv 466
                   +++++ e l+ + +  + +g+   i +la l+ +++++++   lt   + +++++++++++ +i++ +  +++g+
   EEA19485.1 435 -LKRIRGEPLPEHRWSlGKWGMainIAALAYLCPVFVFAFFP--LTSTVTVSTMNWSVVMYLGVIFFATAYYWLGG 507
                  .33334445555544413333300033333334444444443..44446667788888899999888888888775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (522 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1046  (0.0583412); expected 358.6 (0.02)
Passed bias filter:                      359  (0.0200234); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.70u 0.35s 00:00:01.04 Elapsed: 00:00:00.56
# Mc/sec: 2830.98
//
Query:       EEA19486.1  [L=499]
Description: cytochrome P450 monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.5e-41  140.8   0.0    8.9e-41  140.1   0.0    1.3  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.1   0.0     5e-45   8.9e-41       6     457 ..      42     487 ..      38     493 .. 0.78

  Alignments for each domain:
  == domain 1  score: 140.1 bits;  conditional E-value: 5e-45
                 EHHCCHCHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHHHHHHH CS
        p450   6 plplvgnllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkklRrfltp 104
                 p++ ++ l++ ++++e++  +  l++++gp++rl +++ +v  + g   +      k++  s+++ ++ +++      ++g   ++ +k +  +  + +
  EEA19486.1  42 PITSLWILHKRKTGNEIKT-IYCLHRQHGPVVRLGPNEISVNSIDGLRTIYTGGFEKTSWYSDNFLNFGTDN---LVSTRGYKPHSIQKRMLSHVYS-K 135
                 7788899999998888888.999**********999999998888887777777777666666666666665...6666666666655444444444.4 PP

                 HHTSH.STTTHHHHHHHHHHH..HHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCCCHHHTC CS
        p450 105 tltsf.gklsleelveeeaed..lveklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelssllskssvqllllfpllky 200
                 +++++   l+ ++ +  ++++  l++kl ++   ++ +++ +ll+ +  d+ +  lFg++++       +++++ v++       ++ +l+  f++l++
  EEA19486.1 136 SFLQNsPDLQRVSSIIVVGRIlpLLDKLAQT---QEAINVLPLLQGIGQDFTSAYLFGSEYG-------TDFIRDVAKRE-----QWLDLYEKFKVLHP 219
                 4444445553444333343331145555554...4457*********************988.......45788888884.....45566777776666 PP

                 CSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHH CS
        p450 201 lptkllrklkeavkklkdlldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqekl 299
                     l++  + +    +++ d l e +  + + +  +++  +++    +k+ ++  + ++  la ++l+ l+aG++T     +++L eL ++P++q++l
  EEA19486.1 220 KERYLGEFEQGCLALCDKVSDDLKEGKTGSNQGT--QPVVYAQFYRCLEKDPED-WERKRLTLASEMLDHLIAGHETLGISFTYTLWELSQRPDLQARL 315
                 6666666666666666666777777777777776..455555544333312333.4688999************************************* PP

                 HHHHHHHCCTTT...........T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS....CEEETT.EEE-TT-EEEEEHHHHHT-TTTSSSTTS CS
        p450 300 reEidevlgdkr...........eptyddlqklpyldavikEtLRlhpvvplllpRevtk....dvvirg.ylipkGtevivnlyalhrdpevfpnPee 382
                 r E+    +  r            p+ + l +lp+ld +i+EtLRlh++vp   pR+v++    +v+i+g  +ip Gt+v+ ++ +lhr  +v+pnP+e
  EEA19486.1 316 RAELLGLSPTLRiassenekdsaLPSARSLDNLPLLDSIIRETLRLHTPVPGPQPRVVPSsssqPVTIEGyTDIPGGTIVSSSAFSLHRVVDVYPNPDE 414
                 ***99887776777788899999**********************************9877778******778************************** PP

                 --GGGGB-TTS.CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGEEESSCSSEEESS CS
        p450 383 FdpeRFldekg.nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdpppileksglllppk 457
                   peR+l+ +  ns+  +  f  FG G R+CiG +lA   lkl+++ +  nF+ ++ +++ +++ +     + ppk
  EEA19486.1 415 WLPERWLNPDSgNSEAMNRLFWTFGSGGRMCIGSNLALQVLKLVVGAIYTNFTTSIVDDEGIEQEDS---YIAPPK 487
                 *******9877699999999***********************************988777776665...455555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (499 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       479  (0.0267165); expected 358.6 (0.02)
Passed bias filter:                      446  (0.0248759); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.76u 0.37s 00:00:01.12 Elapsed: 00:00:00.58
# Mc/sec: 2577.12
//
Query:       EEA19487.1  [L=110]
Description: hypothetical protein PMAA_002790 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (110 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       240  (0.0133861); expected 358.6 (0.02)
Passed bias filter:                      175  (0.00976072); expected 358.6 (0.02)
Passed Vit filter:                        10  (0.000557756); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.54
# Mc/sec: 617.38
//
Query:       EEA19488.1  [L=321]
Description: endo xylanase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.7e-36  123.7   0.0    1.1e-35  123.4   0.0    1.0  1  Glyco_hydro_43  Glycosyl hydrolases family 43


Domain annotation for each model (and alignments):
>> Glyco_hydro_43  Glycosyl hydrolases family 43
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.4   0.0   6.2e-40   1.1e-35       5     279 ..      25     310 ..      22     316 .. 0.84

  Alignments for each domain:
  == domain 1  score: 123.4 bits;  conditional E-value: 6.2e-40
                     SBCSSEESEEEEEETTCEEEEEEEBTEESEEEEEEESSSSSCEEEEE..CEESTTTCSTTTEECTEEEEEE.EETTEEEEEEE.EEETTCCCSEE CS
  Glyco_hydro_43   5 vlsgfypDpsilrvgedyYlvtstfewfpglrifhSkdLvnWkqvgr..vlerrsqlsmkgknasWAPeis.khdgkyylyyt.atkkgeakqgi 95 
                     vl+ + pDps++ ++++yY + +t  +  + ++ +S d  +W++ ++  +l  +   ++++++ +WAP++   +dg+y +yy+ a + ++ k+++
      EEA19488.1  25 VLNSDFPDPSLIETSSGYYAFGTTG-NGVNAQVATSPDFNTWTLLSStdALPGPFPSWVASSPEIWAPDVLvLADGTYVMYYSaAAASDSSKHCV 118
                     78999***************99996.67889************9876114555556678999999****87489*********87788999999* PP

                     EEEEESSTTS--EECEESSCS...TSSECEEEEEEETTSEEEEEEEEEHCC......CSEEEEEEEEEETTTTEEEEEEEEEEECGCCTCTTBBE CS
  Glyco_hydro_43  96 fvvtadspeGpwsdpiklkts...gssgiDpslfedddGkkYlvwgqwdkr......eghseiylaeldddtlklkgektklikagtelkglkvt 181
                     + +t++speGp++  ++ ++    ++++iD++ f+d dG+ Y+v++   ++      ++   i+l+++++ +++ +g++ +li + +   ++ + 
      EEA19488.1 119 GAATSTSPEGPYTPVNSYVACpldQGGAIDANGFIDSDGTIYVVYKIDGNSldgdgtTHATPIMLQQMEAGGTTPTGSPIQLI-DRS-DLDGPLI 211
                     *************999987669999********************99777789999878889*****************5555.555.59999** PP

                     EEEEEEEETTEEEEEEEESTSSTT.EEEEEEEESSTTSGGEEE..CTCCSEE.T...BTTSTSEEEEEEEEEE-TTSSEEEEEEEESCCTTCCGT CS
  Glyco_hydro_43 182 EGPhlykrdgyyYLlaaeggtgse.yavvvarsksllgPyewk..kknpiltsr...speepiqgpGHaslvetpdgewyivyhagrpegrglyt 270
                     E+P l+   g+yYL ++ +  ++e y++++a ++s++gP+ ++  +  p+l +    s++ +++ pG a++  +  g+  +++ + +    ++  
      EEA19488.1 212 EAPSLLLSSGIYYLSFSSNYYNTEyYDTSYAYATSIRGPWTKQsaPYAPLLVTGretSNDGALSAPGGADFSVD--GTKILFHANLNG---QNIS 301
                     **********************9999999***********876115556666656889999*********9877..544555555555...6677 PP

                     TSSEEEEEE CS
  Glyco_hydro_43 271 lgRetllqr 279
                      gR +++  
      EEA19488.1 302 GGRALFAAS 310
                     777776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (321 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       333  (0.0185733); expected 358.6 (0.02)
Passed bias filter:                      256  (0.0142785); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 2117.95
//
Query:       EEA19489.1  [L=495]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.3e-37  128.2  29.9    3.3e-37  128.2  29.9    1.5  1  MFS_1     Major Facilitator Superfamily
    9.6e-13   47.8   6.4    9.6e-13   47.8   6.4    2.2  2  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  128.2  29.9   3.7e-41   3.3e-37       3     350 ..      60     441 ..      58     444 .. 0.84

  Alignments for each domain:
  == domain 1  score: 128.2 bits;  conditional E-value: 3.7e-41
       MFS_1   3 laaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll.fasslw.lllvlrvlqGlga 99 
                 l+a++ +l++sil+pa   ++a   g+s  +  l l+ly +g++++ ++++++s+ +Grr  +l ++++ a++ ++++ + s     ++v r+++G+++
  EEA19489.1  60 LLALVGSLGSSILTPADE-TIAVYVGVSNEVSVLNLSLYVIGFVLGPIVWAPISEIWGRRISILPAVFFQAIF-CIATgV-SRNAvSVFVTRFFAGFFG 155
                 778899999*******99.9*****************************************************.555546.666768************ PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllgglla..sslgWravfyilaivsllafvlfllllpeepperkrkspkeee........ 188
                 +a ++++ a++ d+++ke rg a++l++++++ G++lgpl+g++l+    lgWr++ yi ai ++++f l ++ lpe  p    k+++++         
  EEA19489.1 156 SAPISNVTAALGDMWSKETRGTAVSLYAVAVNGGPALGPLIGAALVlnNDLGWRWASYIQAIWGFVVFTLTFFCLPEVFPLVLLKRKAQQIrmetndqr 254
                 *******************************************888667888*****************988888888888888888888899999999 PP

       MFS_1 189 ........kgtgpaplvp....awkallkdpvlw.illialllfffgfsglltllplylqevlgls.glllaglllallalvgailallagrls.dr.. 270
                         + ++++ l++    ++++l++ p +  i+++a+++ + +++++l l+p+ +q+++g+s  + ++ +l  l+++++ ++  ++ ++  +r  
  EEA19489.1 255 yyhphehmQLDFHSILTKqlsrPLRMLFTEPIVTcIAFYASFVYG-VMYLTLELFPIVFQKQRGWSpVVASLPFLGLLIGVISSVGVNIWNQYRyNRis 352
                 99999999444444444455557********77666777777776.8888999999999*******743444444444455555557777777779955 PP

       MFS_1 271 ......lgrrrrlllallllllaalglallavtssavllll....vlvliGfglgfvfpsllalasdlappeeagtasglfntagslgga 350
                       + ++ rl  + ++++++++gl+++++t +++ +++    + v+iG+g+ ++f   l+++ d++   +a++ +++++++ sl++a
  EEA19489.1 353 raangaTVPEARLPPMAFGAVFMVVGLFWFGWTAEPPHHWVlpclAAVFIGIGFNCIFQQCLNFLIDVYR-IYAASSTAAVTFLHSLMAA 441
                 555555555************************8887777777778899***999999999999999994.7788888888888887765 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.8   6.4   1.1e-16   9.6e-13      45     193 ..      87     232 ..      47     310 .. 0.88
   2 ?    0.8   0.8     0.019   1.7e+02      77     119 ..     366     409 ..     363     455 .. 0.80

  Alignments for each domain:
  == domain 1  score: 47.8 bits;  conditional E-value: 1.1e-16
                 ..HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHH CS
    Sugar_tr  45 svlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvsly 143
                 +  s l +s++++G ++G ++  ++++++GR+ s+l a+++  i  + ++++    +   ++v R+++G++  +    v+  ++ +  k+ Rg+ vsly
  EEA19489.1  87 NEVSVLNLSLYVIGFVLGPIVWAPISEIWGRRISILPAVFFQAIFCIATGVSR---NAVSVFVTRFFAGFFGSAPISNVTAALGDMWSKETRGTAVSLY 182
                 34677889*********************************************...788899************************************* PP

                 HHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS.-- CS
    Sugar_tr 144 qlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllfl.PE 193
                  +a+  G  ++  +g++l  +++  gwr+  ++q+++  +++ l +f+ PE
  EEA19489.1 183 AVAVNGGPALGPLIGAALVLNND-LGWRWASYIQAIWGFVVFTLTFFClPE 232
                 ********************999.**************9999998775255 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.019
                 HHHHHHHHHHHHHHHHHH-TTTTSS-TGG.GGGHHHHHHHHHHH CS
    Sugar_tr  77 kslliaavlfvigavlqaaakgknsvevl.ivgRvlvGigvGla 119
                 + ++++av++v+g +  +++ +  +++vl +++ v++Gig  ++
  EEA19489.1 366 PPMAFGAVFMVVGLFWFGWTAEPPHHWVLpCLAAVFIGIGFNCI 409
                 67899999999999999999988666666488899999987655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (495 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       693  (0.0386525); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.26s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 3333.85
//
Query:       EEA19490.1  [L=281]
Description: elongation factor 2 kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.4e-49  168.0   0.2    3.1e-49  167.6   0.2    1.1  1  Alpha_kinase  Alpha-kinase family


Domain annotation for each model (and alignments):
>> Alpha_kinase  Alpha-kinase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  167.6   0.2   1.7e-53   3.1e-49       1     184 []      71     254 ..      71     254 .. 0.91

  Alignments for each domain:
  == domain 1  score: 167.6 bits;  conditional E-value: 1.7e-53
                   EE-SSEEEEEESSSHHT-TT-EEEEEEE-STCCTT-HHHHHHHHHHHHHHHHHHHHHH......HT--SS--EE---EEEEETTS--CS....EEEE CS
  Alpha_kinase   1 aegalrkafkakvlkgdekgnklVaKefkkkaeqkelelykeevkvqalakelakeFnakarakekkppkkieflealvlelkeesskk....lflv 93 
                   a+g++r++ k+k+l+g++kg+++VaK+fk+ a   + +++  ++k+ ++a e++++Fn     + +  +k i++ ++ v++++++ +++    ++l+
    EEA19490.1  71 AQGTFRWVAKGKYLSGPRKGQRCVAKWFKNGAVF-SDDFFCLDIKAVDKALEIVDRFN-----QLHIINKVIKINMPAVWRFDDDCEEDwagqMALC 161
                   69*******************************9.***********************.....44445555777777777667666666333377** PP

                   EE---S-EEE-B-TTS-B...-SS-SHHHHHHHHHHHHTTTS-EEE--EE....ETTEEES-EEE-TT--SS-TT--HHHHHHHHHHHBB--HHH CS
  Alpha_kinase  94 EpylegefkKynsnsgyvkedselretmqAFshFtYeasggqllvcDlqG....vgnlLTDpaIhtkdkkrfgdtnlgeegiakFfetHkCnkic 184
                   Epy+ ++++K+nsn+g++++++e+ ++mqA shF+Y+ s+g +++cDlqG     +++L+Dp+I+++++ r+g t+lg eg+ +Ff++H+Cn++c
    EEA19490.1 162 EPYI-HNYQKWNSNNGWHDDSTEWGKVMQAISHFSYHTSSGYYVLCDLQGgihqHEVILSDPVILSQNR-RYGITDLGLEGMGTFFSKHTCNEFC 254
                   ****.9************99******************************976667*************.************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (281 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       534  (0.0297841); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 1970.24
//
Query:       EEA19491.1  [L=100]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-06   27.8  22.9    1.1e-05   25.2  22.8    2.0  1  Ifi-6-16  Interferon-induced 6-16 family
  ------ inclusion threshold ------
        4.1    7.7   5.2        5.2    7.3   5.2    1.2  1  CD99L2    CD99 antigen like protein 2


Domain annotation for each model (and alignments):
>> Ifi-6-16  Interferon-induced 6-16 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2  22.8   1.2e-09   1.1e-05      11      77 ..      10      84 ..       1      87 [. 0.75

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 1.2e-09
    Ifi-6-16 11 PvvlsalGFtaaGiaag..SlAAkmm..SaaAianG..GgVaaGslvAvlQSaGaaGlsaaa..tallgsvGaav 77
                 ++l+ +GFt  G+ ++  Sl +++   S+aA+a+   G+VaaGs++A+lQSaGa G++a++  + ++ +vGaa+
  EEA19491.1 10 ATILNIAGFTGVGVQSEllSLPSWLKpgSLAATAQSalGNVAAGSTFAALQSAGAGGAAALGtiNGVVQGVGAAI 84
                457999*******9875556666664445555554333********************99884467899999986 PP

>> CD99L2  CD99 antigen like protein 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   5.2   0.00058       5.2     102     131 ..      59      88 ..      37      92 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.00058
      CD99L2 102 nddkgsdetaetgtiAgivsavamAlvGAv 131
                  ++ g++  a+ gti g+v  v+ A++G +
  EEA19491.1  59 LQSAGAGGAAALGTINGVVQGVGAAILGSA 88 
                 34788999999*****************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (100 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       427  (0.0238162); expected 358.6 (0.02)
Passed bias filter:                      221  (0.0123264); expected 358.6 (0.02)
Passed Vit filter:                        10  (0.000557756); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.39u 0.26s 00:00:00.65 Elapsed: 00:00:00.43
# Mc/sec: 701.56
//
Query:       EEA19492.1  [L=408]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.6e-16   59.4   0.2    3.7e-10   39.3   0.0    2.3  2  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.3   7.2e-08    0.0013       1     117 [.     154     281 ..     154     288 .. 0.81
   2 !   39.3   0.0   2.1e-14   3.7e-10     148     238 ..     289     374 ..     283     384 .. 0.86

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 7.2e-08
  Fungal_trans   1 ldrffsnfhpqfpilhkpsflpkt.................ssenssksayasplll...lailalGalfsesetkesnssltsesqefiafplrae 77 
                   ld++fs +h  +p +h   f+++                   + + + ++y++++++   +a +a+G++f++   +e+++ ++        f+ r +
    EEA19492.1 154 LDSYFSSVHIFYPWVHSVAFWEECdrlwtvsngetqtpfqnLDIGLGGTNYTKHIFFctlNAEFAIGYQFTDFSLNEKENLAS-------VFFGRMK 243
                   79*********************9*999**********9994455555555555555555****************9833333.......3455666 PP

  Fungal_trans  78 ilihedfsspssslwilqsLlllelyektssdralherhh 117
                    l+ +d+ +  s + ++q+Lll+  y++++++ + +++++
    EEA19492.1 244 DLL-NDALDGGS-ISHVQALLLAGHYLLCTQYPSRCWNIF 281
                   666.67777777.************************965 PP

  == domain 2  score: 39.3 bits;  conditional E-value: 2.1e-14
  Fungal_trans 148 eaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddlwesddaseetlvetklsneeksrkiasfllaLkkilskiagsllsi 238
                   eae+rrR+w++++ lD t+++ lGrp +   ++ ++pL    dd+ +  +++  ++++           +  + ++L++il++i++ ++ +
    EEA19492.1 289 EAEIRRRVWYGCYQLDMTVSMTLGRPAF-MRTCSDVPLLSPIDDEYIKPNRDPMDQPD----GVFPIIAFIGQNIKLAQILGEILDRIYHL 374
                   59*************************5.46666666666677778888888888888....569999******************99976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (408 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       441  (0.024597); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.31s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2774.13
//
Query:       EEA19493.1  [L=678]
Description: hypothetical protein PMAA_002850 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
  ------ inclusion threshold ------
      0.045   13.3   0.8      0.082   12.5   0.0    1.9  2  zf-C2H2_12  Zinc-finger C2H2-type


Domain annotation for each model (and alignments):
>> zf-C2H2_12  Zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   4.6e-06     0.082      18      64 ..     206     253 ..     204     257 .. 0.88
   2 ?   -3.6   0.2      0.48   8.7e+03      41      49 ..     491     499 ..     484     503 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 4.6e-06
  zf-C2H2_12  18 pqrrglvCmvCgeslaslklstikrHIrqvH.Peslslseeekeaile 64 
                 +qr+  +C  C ++   ++   +krH++++H ++s+ l  +e+e+++ 
  EEA19493.1 206 SQRDAYLCKLCPSAVRITSRGAFKRHVNEKHeAKSMFLYLTERELVMA 253
                 5788899************************66789999999999876 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 0.48
  zf-C2H2_12  41 krHIrqvHP 49 
                  rH r++H 
  EEA19493.1 491 ARHLRRCHN 499
                 699999995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (678 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       753  (0.041999); expected 358.6 (0.02)
Passed bias filter:                      520  (0.0290033); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.46
# Mc/sec: 4462.30
//
Query:       EEA19494.1  [L=387]
Description: RRM domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.027   14.3   0.0      0.049   13.5   0.0    1.4  1  RRM_1     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   2.7e-06     0.049       1      56 [.     101     160 ..     101     166 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.7e-06
                 EEEESETTTSSHHHHHHHHHT..TSCE.EEEEEEEE.TTTSEEEEEEEEESSHHHHHHHH CS
       RRM_1   1 lfVgnLppdvteeeLkelFsk..fGpi.ksiklvrd.etgkskgfafVeFeskedAekAl 56 
                 lf++ L + +t+++++ + ++   ++  k+++ +    +gksk  a+VeF++  +A++ +
  EEA19494.1 101 LFISELFWWTTDDDIRGWINEahAEDElKDVTFSEHkVNGKSKSQAYVEFTTLQAATAVK 160
                 799999999999999999999644444589999999*****************9999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (387 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       656  (0.0365888); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.70u 0.37s 00:00:01.06 Elapsed: 00:00:00.58
# Mc/sec: 2010.84
//
Query:       EEA19495.1  [L=68]
Description: protein translocation complex subunit Sss1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.9e-15   55.9   0.0    3.4e-15   55.7   0.0    1.1  1  SecE      SecE/Sec61-gamma subunits of protein translocation 


Domain annotation for each model (and alignments):
>> SecE  SecE/Sec61-gamma subunits of protein translocation complex
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.7   0.0   1.9e-19   3.4e-15       1      53 [.      13      65 ..      13      67 .. 0.94

  Alignments for each domain:
  == domain 1  score: 55.7 bits;  conditional E-value: 1.9e-19
                HHCHHHHHHHHHCCCCCHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HH CS
        SecE  1 kkFfkevkaElkKVtWPtrkEllkttvvVlvfvvimglflflvDlvfskli.nl 53
                k+F+++  ++++++t+P+++E+lk++ +V v++vimg+++++v+l++ +++ n+
  EEA19495.1 13 KDFVRDGMQFINRCTKPDKREFLKISQAVGVGFVIMGAIGYFVKLIH-IPVnNV 65
                58********************************************9.999555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (68 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       390  (0.0217525); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.34s 00:00:00.82 Elapsed: 00:00:00.51
# Mc/sec: 401.22
//
Query:       EEA19496.1  [L=659]
Description: WD repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.6e-23   81.9  13.9    7.6e-05   23.4   0.1    7.9  7  WD40          WD domain, G-beta repeat
    9.3e-05   22.7   0.0       0.11   12.9   0.0    4.0  4  ANAPC4_WD40   Anaphase-promoting complex subunit 4 WD40 domai
    0.00026   19.6   2.4      0.055   12.0   0.1    3.8  4  Cytochrom_D1  Cytochrome D1 heme domain
     0.0011   19.4   0.4        0.2   12.2   0.1    3.6  3  PQQ_3         PQQ-like domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.7   0.0   0.00077       3.5      18      38 .]     256     276 ..     240     276 .. 0.88
   2 !    5.7   0.0    0.0065        29      13      29 ..     298     314 ..     287     325 .. 0.81
   3 !   11.6   0.0   9.5e-05      0.42       5      38 .]     342     375 ..     339     375 .. 0.88
   4 !   23.4   0.1   1.7e-08   7.6e-05       3      38 .]     381     419 ..     379     419 .. 0.79
   5 !   12.4   0.0   5.1e-05      0.23       7      38 .]     432     464 ..     427     464 .. 0.91
   6 !   13.9   0.0   1.7e-05     0.078       5      38 .]     507     547 ..     504     547 .. 0.76
   7 !    7.7   1.2    0.0015       6.9       4      37 ..     579     621 ..     576     622 .. 0.71

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00077
                 EETTSSEEEEEETTSEEEEEE CS
        WD40  18 fspdgawlasGsdDgtvriWd 38 
                 fs+dg++++s+  D +vr++d
  EEA19496.1 256 FSDDGNFFFSCNQDFKVRMYD 276
                 9******************98 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.0065
                 EEEEEEETTSSEEEEEE CS
        WD40  13 vtslafspdgawlasGs 29 
                 +t+   spd++wla +s
  EEA19496.1 298 ITDATLSPDNKWLAVSS 314
                 999999*******9887 PP

  == domain 3  score: 11.6 bits;  conditional E-value: 9.5e-05
                 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   5 rtltGHssvtslafspdgawlasGsdDgtvriWd 38 
                 r++ G ++++sl+fs dg+ +++G+ + +v ++d
  EEA19496.1 342 RHYNGRFGIWSLRFSGDGREIVAGTANSSVIVYD 375
                 66777766****************99****9998 PP

  == domain 4  score: 23.4 bits;  conditional E-value: 1.7e-08
                 EEEEEESS.SSEEEEE.EETTSSE.EEEEETTSEEEEEE CS
        WD40   3 clrtltGH.ssvtsla.fspdgaw.lasGsdDgtvriWd 38 
                 ++ +l+ H ++v++++  +++++  l sGsdD t+r+Wd
  EEA19496.1 381 PILELEKHqDDVNAVCfGDSSSPHiLYSGSDDTTIRVWD 419
                 6778899*888*****95555555266***********9 PP

  == domain 5  score: 12.4 bits;  conditional E-value: 5.1e-05
                 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 + GH  + t ++   dg++++s ++D+t ++Wd
  EEA19496.1 432 FVGHtEGLTYVDSKGDGRYVLSNGKDQTMKLWD 464
                 789*777**************8899*******9 PP

  == domain 6  score: 13.9 bits;  conditional E-value: 1.7e-05
                 EEEESSSS....EEEEE...EETTSSEEEEEETTSEEEEEE CS
        WD40   5 rtltGHss....vtsla...fspdgawlasGsdDgtvriWd 38 
                  t++GH+     +++      s +++++ +Gs+Dg+v++++
  EEA19496.1 507 VTYRGHKVlrtlIRCHFsppSSTNSRYVYTGSYDGKVYVYN 547
                 5899**434556633335889999999************97 PP

  == domain 7  score: 7.7 bits;  conditional E-value: 0.0015
                 EEEEESS.SSEEEEEEETTSSEEEEEET........TSEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgawlasGsd........DgtvriW 37 
                 +++++ H + v++++++p+ + la++++         ++++ W
  EEA19496.1 579 MGIFDNHgTIVRDVSWHPSVPILAASCWnsngesrgSCSIHSW 621
                 578999*4448************98876444444445555555 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0      0.56   2.5e+03      46      69 ..     256     279 ..     252     289 .. 0.88
   2 ?   -0.2   0.0      0.28   1.3e+03      40      67 ..     297     324 ..     282     336 .. 0.83
   3 !   12.9   0.0   2.4e-05      0.11      41      89 ..     350     397 ..     340     400 .. 0.89
   4 ?    3.3   0.0     0.023     1e+02      35      60 ..     583     608 ..     576     625 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.56
  ANAPC4_WD40  46 WkpdgklLavaysdgevrlldaes 69 
                  ++ dg+++    +d +vr++d ++
   EEA19496.1 256 FSDDGNFFFSCNQDFKVRMYDTSN 279
                  7899****************9876 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.28
  ANAPC4_WD40  40 evrsLaWkpdgklLavaysdgevrllda 67 
                  ++++   +pd+k Lav+  + +v l + 
   EEA19496.1 297 TITDATLSPDNKWLAVSSIQRQVTLAST 324
                  677778899*******999999998876 PP

  == domain 3  score: 12.9 bits;  conditional E-value: 2.4e-05
  ANAPC4_WD40  41 vrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                  + sL+++ dg+ ++ ++++++v ++d+e+++ + +l+ ++++ v+ + +
   EEA19496.1 350 IWSLRFSGDGREIVAGTANSSVIVYDIETQRPILELEKHQDD-VNAVCF 397
                  779**********************************99996.777666 PP

  == domain 4  score: 3.3 bits;  conditional E-value: 0.023
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdg 60 
                  d+++  vr+++W+p+  +La ++ ++
   EEA19496.1 583 DNHGTIVRDVSWHPSVPILAASCWNS 608
                  678999***************99665 PP

>> Cytochrom_D1  Cytochrome D1 heme domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0      0.03   1.4e+02      40      94 ..     253     313 ..     246     320 .. 0.72
   2 ?    0.8   0.0     0.032   1.4e+02     289     348 ..     365     423 ..     359     430 .. 0.75
   3 ?    2.1   0.1     0.013        57      44      67 ..     445     468 ..     438     500 .. 0.77
   4 !   12.0   0.1   1.2e-05     0.055      28      66 ..     512     550 ..     505     578 .. 0.80

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.03
                   EEE-TT.SSEEEEEETTSEEEEEESSSSS...EEEEEE.-.SSEEEEEE.E--TTSEEEEE CS
  Cytochrom_D1  40 srvfasdgRyvyvigRDgkvtliDLwake...ivaevk.i.Glnarsva.vSqddryvivg 94 
                   s  f+ dg + +    D kv ++D  + +     ++v  + G  ++  a  S d+++++v+
    EEA19496.1 253 SGQFSDDGNFFFSCNQDFKVRMYDTSNPHdwrYYKTVPfMgGQWTITDAtLSPDNKWLAVS 313
                   667999******************9887766655565312144455433146788887776 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.032
                   -SSHT-EEEEETTBT-EEE-HHHHHT--EEEEEE-TTSS.EEEEEEE--SSEEEEEETTTT CS
  Cytochrom_D1 289 npdndsvaviDkktlekvltlaesaglkvvhvEfnkdGd.evwlSvwdgkdalvvyDdktl 348
                   +  n sv v+D +t   +l+l+++ +  v  v f +    +++ S  d ++ + v+D +++
    EEA19496.1 365 GTANSSVIVYDIETQRPILELEKHQD-DVNAVCFGDSSSpHILYSGSD-DTTIRVWDRRSM 423
                   556899****************9999.788888877665144444444.448888888776 PP

  == domain 3  score: 2.1 bits;  conditional E-value: 0.013
                   TT.SSEEEEEETTSEEEEEESSSS CS
  Cytochrom_D1  44 asdgRyvyvigRDgkvtliDLwak 67 
                     dgRyv+  g+D +++l DL + 
    EEA19496.1 445 KGDGRYVLSNGKDQTMKLWDLRKM 468
                   569*****************9654 PP

  == domain 4  score: 12.0 bits;  conditional E-value: 1.2e-05
                   EEEEE-STTEEEEEE-TT.SSEEEEEETTSEEEEEESSS CS
  Cytochrom_D1  28 lavletgyalHisrvfasdgRyvyvigRDgkvtliDLwa 66 
                    +vl t+   H s+ ++ + Ryvy+ + Dgkv ++ + a
    EEA19496.1 512 HKVLRTLIRCHFSPPSSTNSRYVYTGSYDGKVYVYNIDA 550
                   6899999*************************9987654 PP

>> PQQ_3  PQQ-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.0     0.072   3.2e+02      20      40 .]     358     378 ..     346     378 .. 0.86
   2 ?   -0.2   0.0      0.34   1.5e+03      23      40 .]     405     422 ..     396     422 .. 0.89
   3 !   12.2   0.1   4.4e-05       0.2      18      38 ..     528     548 ..     521     550 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.072
       PQQ_3  20 dgglvyvgtgdGtlyAlDaet 40 
                 dg+ +++gt + ++  +D et
  EEA19496.1 358 DGREIVAGTANSSVIVYDIET 378
                 566699************998 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.34
       PQQ_3  23 lvyvgtgdGtlyAlDaet 40 
                 ++y g++d t++  D ++
  EEA19496.1 405 ILYSGSDDTTIRVWDRRS 422
                 5899********999876 PP

  == domain 3  score: 12.2 bits;  conditional E-value: 4.4e-05
       PQQ_3  18 avdgglvyvgtgdGtlyAlDa 38 
                  +  ++vy+g++dG++y ++ 
  EEA19496.1 528 STNSRYVYTGSYDGKVYVYNI 548
                 556689***********9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (659 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       505  (0.0281667); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.77u 0.38s 00:00:01.14 Elapsed: 00:00:00.58
# Mc/sec: 3435.82
//
Query:       EEA19497.1  [L=587]
Description: MFS siderophore iron transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.3e-24   84.3  47.6    4.6e-22   78.4  42.7    2.9  2  MFS_1     Major Facilitator Superfamily
    2.2e-06   26.4  26.0    4.5e-06   25.4  26.0    1.4  1  TRI12     Fungal trichothecene efflux pump (TRI12)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.4  42.7   5.2e-26   4.6e-22       1     353 []      74     492 ..      74     492 .. 0.85
   2 ?   -0.3   0.0     0.043   3.8e+02     148     173 ..     546     572 ..     524     584 .. 0.52

  Alignments for each domain:
  == domain 1  score: 78.4 bits;  conditional E-value: 5.2e-26
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.sslwlllvlrvlqGlg 98 
                 +++++f++a+++sil++++p ++++d+  s+s ++ ++ +  + +a+  +pl+ + d +Gr   ++++ ++  lg l+l+ + ++l +++++ v+  +g
  EEA19497.1  74 IWFLYFVNAFQSSILYSLIP-FVTSDFE-SHSLLNVIYIVGNAMSAAVFIPLAKVLDVWGRAQGYMFMTVCCTLG-LVLMAScHNLSMFCAAYVFYIIG 169
                 699*****************.*******.999999988886666666666666666*******************.4444246**************** PP

       MFS_1  99 agalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllll.....peepperkrkspkeee.... 188
                  ++++  + +l+ad ++ ++rg+a+++ s+ + + a  gp ++  ++ +++Wr+ f  +ai++ +++    l++     + ++ + + ++    e    
  EEA19497.1 170 FSGITYCVDVLTADASKLKNRGLAYAFTSSPYMITAFAGPKVSNDFYYNINWRWGFGCFAIIFPVVAA--PLYFvlrrsLKNADRMGLVKR---Eksgr 263
                 ******************************************************************77..344422343333333333333...14469 PP

       MFS_1 189 .................................................................kgtgpaplvpawkallkdpvlwillialllfffg 222
                                                                                     +p+pl++ ++ l  + v+ ++l+ + +    
  EEA19497.1 264 tllqsiwyntlefdaigvvlfsvgltvfflpfdlasyapngwasgyiiamivvgfvllvtfafyeWLLAPKPLFN-FSFLSDRTVIGACLLDATYQI-S 360
                 999999*************************************99999999999999999999999999999999.777777776654444444442.6 PP

       MFS_1 223 fsglltllplylqevlgls....glllaglllallalvgailallagrlsdrlgr.rrrlllallllllaalglallavtssavllllvlvl.iGfglg 315
                 ++    +++++lq v +ls    g++ ++     + +v+ il +++g+ ++r+g+ ++ l++a++l ++a  +++++  ++ +v +l+++ + i++g++
  EEA19497.1 361 YYCWNNYFTSFLQVVNDLSidtaGYVNNT-----FNVVSGILLFIVGYSIRRTGKfKWLLYIAVPLYVFAQGLMIYFRRPNQSVGYLIMCQIfISIGGS 454
                 666****************5555555555.....55555555999**********99999999999999999999999999999999988776999999 PP

       MFS_1 316 fvfpsllalasdlappeeagtasglfntagslggalgp 353
                 ++ ++ ++ +   +  ++ +++++l n++g++gga+g+
  EEA19497.1 455 IFIILQQVSIEAAVDHQHVAAVLALLNVVGTVGGAIGA 492
                 99999999999999**********************96 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.043
       MFS_1 148 lgWravfyilaivsllafv.lfllllp 173
                 +g+  + +++a+ +++++  +++++++
  EEA19497.1 546 YGYAQTRMLAAGTGIMGLAfIWIFFFR 572
                 444444444444444443323334443 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.4  26.0   5.1e-10   4.5e-06      44     477 ..      65     511 ..      29     537 .. 0.68

  Alignments for each domain:
  == domain 1  score: 25.4 bits;  conditional E-value: 5.1e-10
       TRI12  44 asfaafslnvvatyfvlqasasalpnilqdvg.qsensslfstlwttgqavsilv...mgrltdrfgrrpfvilthilglvgaivgctatkfntllaam 138
                 as+ a+ +n+   yfv    +s l  ++  v  + e +sl+  ++ +g+a+s  v   + ++ d +gr    +   +   +g ++ +++ ++  + aa 
  EEA19497.1  65 ASLIAVFINIWFLYFVNAFQSSILYSLIPFVTsDFESHSLLNVIYIVGNAMSAAVfipLAKVLDVWGRAQGYMFMTVCCTLGLVLMASCHNLSMFCAAY 163
                 78888999********9999999999998876257999************9976633368889*****9877777777778888888888888888888 PP

       TRI12 139 tllgva.agpagasplfvgelmsnktkflgllivsipvvvtsglspylgqrlaiqgswrwifyiy.iitsaiavllivvwyyppsfaqlhg...kkvrk 232
                  +  +  +g + +  ++  +    k + l     s p ++t+ ++p + + +  + +wrw f  + ii   +a  l  v       a+  g   +  + 
  EEA19497.1 164 VFYIIGfSGITYCVDVLTADASKLKNRGLAYAFTSSPYMITAFAGPKVSNDFYYNINWRWGFGCFaIIFPVVAAPLYFVLRRSLKNADRMGlvkREKSG 262
                 765553256777778888888888888899999*****************************8773667788888888877665555544421133333 PP

       TRI12 233 reela.......kldwigiilvivgvslfllgvswggkpnspwnsakviglissglgslvvfalyevygkpvrpivppalfkdtrgfvcillissimga 324
                 r  l          d ig++l +vg ++f+l         + w s  +i +i  g   lv fa+ye    p +p+   +++ d   +    l+ +    
  EEA19497.1 263 RTLLQsiwyntlEFDAIGVVLFSVGLTVFFLPFDLASYAPNGWASGYIIAMIVVGFVLLVTFAFYEWLLAP-KPLFNFSFLSDRTVI-GACLLDATYQI 359
                 4444311122125689**************************************************99888.699999988875443.33333333333 PP

       TRI12 325 mnlslviiyp..qqvvnifgsslknweetawmsatasfgtgagvvvlgslfhlvrhirwqilvgalwltaf.lgamssvnrdnknaaialsvlsgfvva 420
                    +    +    qvvn +       + + +++ t  + +g  + ++g  +    + +w + +  + l  f  g m    r n+  ++   +++ + ++
  EEA19497.1 360 SYYCWNNYFTsfLQVVNDLS-----IDTAGYVNNTFNVVSGILLFIVGYSIRRTGKFKWLLYIA-VPLYVFaQGLMIYFRRPNQ--SVGYLIMCQIFIS 450
                 33333322220134444332.....223334444444444444455566666666666755554.4444441466666666554..4555666666666 PP

       TRI12 421 waqditmllvqf.itt..de.dlgvafavvaaarpfagsiftaafislysnrypkelashl 477
                     i ++l q+ i +  d  ++   +a++     + g+i ++   +++sn +p  l  +l
  EEA19497.1 451 IGGSIFIILQQVsIEAavDHqHVAAVLALLNVVGTVGGAIGATISGTIWSNTFPVALERYL 511
                 6666666665542222112202222334444444455555555555677777777777666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (587 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       851  (0.047465); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.78u 0.35s 00:00:01.12 Elapsed: 00:00:00.57
# Mc/sec: 3101.15
//
Query:       EEA19498.1  [L=276]
Description: enoyl-CoA hydratase/isomerase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      4e-54  183.6   0.0    4.9e-54  183.3   0.0    1.0  1  ECH_1     Enoyl-CoA hydratase/isomerase
    8.3e-31  107.7   0.3    2.1e-27   96.5   0.1    2.5  2  ECH_2     Enoyl-CoA hydratase/isomerase
  ------ inclusion threshold ------
      0.031   14.2   0.0      0.047   13.6   0.0    1.2  1  DoxD      TQO small subunit DoxD
      0.036   13.7   0.0       0.13   11.8   0.0    1.8  2  PrpR_N    Propionate catabolism activator
       0.13   12.4   0.0       0.24   11.5   0.0    1.4  1  DUF4819   Domain of unknown function (DUF4819)


Domain annotation for each model (and alignments):
>> ECH_1  Enoyl-CoA hydratase/isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  183.3   0.0   1.4e-57   4.9e-54       4     249 ..      24     272 ..      22     274 .. 0.95

  Alignments for each domain:
  == domain 1  score: 183.3 bits;  conditional E-value: 1.4e-57
                 TTEEEEEE--CGCTTEE-HHHHHHHHHHHHHHHHSTTECEEEEEEBTSEEEEEB-HHHHHHHHCHHHHHHHCCHHHHHHHH..HHSSSEEEEEE-SEEE CS
       ECH_1   4 agvaviklnrPeavNalsaelltEliqalekleddksvravvLtGgdkaFaaGadlkemaeeekakqallkeevlelwtkl..ytvpkpviaavnGaai 100
                 + +++i+lnrP+++N++++ ++ ++ +    +++d+++ + ++tG+++aF+ Gadl+e  e   +k+ ++++ +   +  l  ++ +kp+iaavnG ++
  EEA19498.1  24 ERIMQITLNRPKKLNSVNKSMSRDIQAIWDLFDQDENLWVGIITGSGRAFCTGADLQEWNEM--NKAGVVNNMDAPGLAGLprRSGKKPIIAAVNGICM 120
                 5799*******************************************************996..7788888888888877744789************* PP

                 THHHHHHHHSSEEEEETTTEEE-GGGGGTS--CTTCHHHHHHHHHHHHHHHHHHHT-EEEHHHHHHCTSSSEEESG.GGHHHHHHHHHHHHHHSCHHHH CS
       ECH_1 101 gGGlelalacDiviaadnasfglnelklGlipgaggtqilarkvGkskAeeilllgkkisaqealkvGlvdkvvpe.eqlleealelaeklaekspaal 198
                 gGG+e+   cD+via+  a f+l+e+k G++p ag  ++l+r++G ++ + ++l+g++++aq + ++Glv++v+   +++++ a+++a+++ ++sp+al
  EEA19498.1 121 GGGFEMIANCDMVIASALAIFSLPEVKRGIVPVAGCLPRLTRTLGLQRTMDLVLTGRNVTAQTLYEWGLVSRVIDSsDDVVHAAVQVAQEMCKNSPDAL 219
                 ************************************************************************98666********************** PP

                 HHHHHHHHHHHH..HHHHHHHHHHHHHHHHHCTSHHHHHHHHHHHTCSH---- CS
       ECH_1 199 rqlkealnakle..dalaeqleaeaklfestfskddikeGlqaflEkrkpefe 249
                    ++a++   e  + +++++++ a+ +  +++  ++ eG+qaf+Ekr+p + 
  EEA19498.1 220 IVGRQAIRLSWEtgSVEEAVSAVAAESYPRLVAGSNFAEGIQAFVEKRPPVWA 272
                 ******9999987789999999******************************7 PP

>> ECH_2  Enoyl-CoA hydratase/isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   96.5   0.1   5.9e-31   2.1e-27       3     175 ..      28     197 ..      26     202 .. 0.91
   2 !    9.0   0.0   0.00025      0.88     248     321 ..     203     275 ..     197     276 .] 0.83

  Alignments for each domain:
  == domain 1  score: 96.5 bits;  conditional E-value: 5.9e-31
                 EEEE--GGGTT-B-HHHHHHHHHHHHHHCC-TT-SEEEEEESSSSECE--B--HHHHHHHHCS-THHHHHHHHHHHHHHHH.HC-SS-EEEEE-BEEET CS
       ECH_2   3 vitLnrpkalNaLslemvralkealkewekddevklvvlkgagekafCAGgDvralyeaakegkkeeeeffreeYklnyli.atypkpvvalmdGivmG 100
                  itLnrpk+lN+++ +m r+++++ + +++d++  + +++g+g +afC G D+++  e +k+g  ++     +   l  l   + +kp++a ++Gi+mG
  EEA19498.1  28 QITLNRPKKLNSVNKSMSRDIQAIWDLFDQDENLWVGIITGSG-RAFCTGADLQEWNEMNKAGVVNN----MDAPGLAGLPrRSGKKPIIAAVNGICMG 121
                 69***************************************88.******************97664....3444555554056689************ PP

                 HHHHHHTTSSEEEE-TT-EEE--GGGGT----TTHHHHHHCSST.THHHHHHHH---B-HHHHHHTTS--EE--GG CS
       ECH_2 101 gGvGlsvhgsfrvvtertvfAmPEtaIGlfPDvGgsyfLsrlpg.elGlylalTGarlkgadalaaglathyvpse 175
                 gG  + +++ + +++  ++f+ PE++ G++P  G+   L+r+ g +  + l lTG++++++ +++ gl + +++s+
  EEA19498.1 122 GGFEMIANCDMVIASALAIFSLPEVKRGIVPVAGCLPRLTRTLGlQRTMDLVLTGRNVTAQTLYEWGLVSRVIDSS 197
                 **********************************9999999877688899**********************9997 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00025
                 HHHHHHHHHHHS-HHHHHHHHHHHHHHTTT--HHHHHHH.HHHHHHHHHHHSSHHHHHHHHTTS-------SSSS CS
       ECH_2 248 wakktletlkkrsPtslkvtleqlrrgrklsslaevlrm.ElrlalrllaekDfveGvrallvdkdkkPkWkpat 321
                  a ++++++ k+sP +l v  +++r + ++ s++e+ +    +   rl+a ++f+eG++a  v+k + P W  ++
  EEA19498.1 203 AAVQVAQEMCKNSPDALIVGRQAIRLSWETGSVEEAVSAvAAESYPRLVAGSNFAEGIQAF-VEK-RPPVWANSK 275
                 678899********************9999999999876145566788889*******996.666.689998765 PP

>> DoxD  TQO small subunit DoxD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.0   1.3e-05     0.047      46     121 ..     116     191 ..     106     209 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 1.3e-05
        DoxD  46 qasiikdlleivvlnrsllvtalvlftlvEiivGlllliGlltRlsslvafalalgialsayWlgstcedEyqigl 121
                 +++ + + +e+++    +   al +f+l E+  G++ + G l Rl+ +  ++ ++ ++l+   + +  + E+++ +
  EEA19498.1 116 NGICMGGGFEMIANCDMVIASALAIFSLPEVKRGIVPVAGCLPRLTRTLGLQRTMDLVLTGRNVTAQTLYEWGLVS 191
                 6677777789999999**********************************************99999999999864 PP

>> PrpR_N  Propionate catabolism activator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   3.7e-05      0.13     122     162 ..     173     213 ..     166     216 .. 0.91
   2 ?   -1.4   0.0      0.43   1.5e+03       5      23 ..     226     244 ..     223     264 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3.7e-05
      PrpR_N 122 vvvGdgvvadlAekaGlksvlltsgkesvrqAieeAleiar 162
                 v+ G +v+a++  + Gl s ++ s+++ v++A++ A+e+++
  EEA19498.1 173 VLTGRNVTAQTLYEWGLVSRVIDSSDDVVHAAVQVAQEMCK 213
                 556899*********************************97 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.43
      PrpR_N   5 ldievvegdleeavelake 23 
                 ++++ ++g++eeav+++ +
  EEA19498.1 226 IRLSWETGSVEEAVSAVAA 244
                 6777888999999987765 PP

>> DUF4819  Domain of unknown function (DUF4819)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   6.8e-05      0.24      28      75 ..     178     228 ..     157     233 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 6.8e-05
     DUF4819  28 eeaaekvyregvvvevktkp...vrfkVklseekeeeekeavlVkRadlRL 75 
                 + +a+++y+ g v +v  +    v+ +V++ +e  +++ +a++V R+ +RL
  EEA19498.1 178 NVTAQTLYEWGLVSRVIDSSddvVHAAVQVAQEMCKNSPDALIVGRQAIRL 228
                 678999*******9987776676799********999999**********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (276 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       375  (0.0209158); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.66u 0.36s 00:00:01.02 Elapsed: 00:00:00.59
# Mc/sec: 1412.38
//
Query:       EEA19499.1  [L=465]
Description: acetyltransferase SidF [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.3e-41  139.7   0.1    7.3e-41  139.2   0.1    1.2  1  Acetyltransf_8  Acetyltransferase (GNAT) domain


Domain annotation for each model (and alignments):
>> Acetyltransf_8  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.2   0.1   4.1e-45   7.3e-41       3     145 .]     280     423 ..     278     423 .. 0.97

  Alignments for each domain:
  == domain 1  score: 139.2 bits;  conditional E-value: 4.1e-45
                     GGGHHHHHHHCTSCCCHHHH-----HHHHHHHHHHHC.STTEEEEEEEETTEEEEEEEEEEGGGCGGGGCS---TT-EEEEEEESSHHHCTTTCH CS
  Acetyltransf_8   3 eaDlellhrWmnrprvaewweeagtleevrellakldadphsepliglldgepvgyfeiYwakedelaeyydaepgdrGiHlligeaeargkglt 97 
                     +++l+l+++W+n+prva+ w+e+gtle++re+l+kl+ dph+  l g+++++ ++yfe+Ywaked+ +++y a ++drG H l+g+a++rg +++
      EEA19499.1 280 DEHLKLFNTWQNDPRVAKGWNETGTLEQHREYLRKLHFDPHVLCLFGRFNETRFSYFELYWAKEDHYGAHYAAGDYDRGRHSLVGDASFRGSQRV 374
                     799******************************************************************************************** PP

                     HHHHHHHHHHHHC.CTT--EEEE--BTT-HHHHHHHHHTT-EEEEEEEE CS
  Acetyltransf_8  98 tallralvhylfa.dprtrrvvvEPdvrNerairllekaGfekekevdl 145
                     + + ++++hy+f+ dprt++vv+EP+++   ++++ +++G +  k vdl
      EEA19499.1 375 NVWYSSCIHYCFLdDPRTANVVGEPKATGGTILSYENSQGLVIDKYVDL 423
                     ************6488************************999998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (465 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       274  (0.0152825); expected 358.6 (0.02)
Passed bias filter:                      247  (0.0137766); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.64u 0.34s 00:00:00.98 Elapsed: 00:00:00.54
# Mc/sec: 2582.02
//
Query:       EEA19500.1  [L=1330]
Description: ABC multidrug transporter SitT [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.9e-91  304.5  24.6    1.1e-51  176.1   7.8    2.2  2  ABC_membrane  ABC transporter transmembrane region
    1.8e-62  209.9   0.0    6.9e-31  107.6   0.0    2.6  2  ABC_tran      ABC transporter
    9.1e-16   58.0   3.6    3.5e-06   26.6   0.8    4.5  3  SMC_N         RecF/RecN/SMC N terminal domain
    1.2e-08   34.5   0.7     0.0028   17.3   0.0    3.2  3  AAA_29        P-loop containing region of AAA domain
    1.1e-07   32.4   1.4      0.011   16.1   0.1    3.1  2  AAA_16        AAA ATPase domain
    1.7e-07   31.6   1.6       0.12   12.6   0.1    4.2  2  AAA_22        AAA domain
    4.7e-06   26.5   0.8      0.052   13.3   0.0    3.5  3  AAA_30        AAA domain
    1.1e-05   25.4   0.1      0.013   15.4   0.1    2.5  2  APS_kinase    Adenylylsulphate kinase
    5.4e-05   23.4   2.3      0.047   13.8   0.7    3.0  2  DUF87         Helicase HerA, central domain
      9e-05   21.8   0.0        0.3   10.3   0.0    2.5  2  Zeta_toxin    Zeta toxin
    0.00012   22.0   0.1       0.06   13.2   0.0    2.5  2  RsgA_GTPase   RsgA GTPase
    0.00036   19.7   0.0      0.068   12.2   0.0    2.3  2  DUF3987       Protein of unknown function (DUF3987)
     0.0017   18.6   0.0        2.9    8.1   0.0    2.7  2  AAA_33        AAA domain
     0.0017   18.9   0.0        3.9    8.0   0.0    2.6  2  AAA_18        AAA domain
     0.0017   18.0   0.3       0.68    9.5   0.0    3.6  4  AAA_25        AAA domain
     0.0024   18.3   0.6         45    4.5   0.0    4.3  4  AAA           ATPase family associated with various cellular 
     0.0029   17.5   1.0       0.25   11.1   0.0    2.8  2  AAA_21        AAA domain, putative AbiEii toxin, Type IV TA s
     0.0057   15.5   0.4       0.18   10.6   0.0    2.7  3  ABC_ATPase    Predicted ATPase of the ABC class
     0.0072   16.9   4.8        1.3    9.4   0.0    2.8  2  AAA_23        AAA domain
     0.0074   16.4   0.0        3.8    7.6   0.0    2.8  2  MMR_HSR1      50S ribosome-binding GTPase
  ------ inclusion threshold ------
      0.011   16.0   0.2         14    6.0   0.2    3.5  2  SbcCD_C       Putative exonuclease SbcCD, C subunit
      0.011   15.7   0.0        4.9    7.1   0.0    3.3  3  AAA_5         AAA domain (dynein-related subfamily)
      0.015   15.1   0.1       0.27   11.0   0.0    2.7  2  DEAD          DEAD/DEAH box helicase
       0.02   14.5   0.0        7.2    6.2   0.0    2.6  2  SRP54         SRP54-type protein, GTPase domain
      0.032   13.4   0.1          7    5.7   0.0    2.6  2  NB-ARC        NB-ARC domain
      0.045   13.2   0.0        2.2    7.7   0.0    2.3  2  KdpD          Osmosensitive K+ channel His kinase sensor doma
      0.066   12.7   0.1         10    5.6   0.0    2.3  2  AAA_7         P-loop containing dynein motor region
       0.09   12.7   4.8       0.34   10.8   0.8    3.0  2  Cad           Cadmium resistance transporter
       0.16   11.7   0.0        7.7    6.2   0.0    2.6  2  AAA_24        AAA domain
       0.16   12.4   0.0         37    4.7   0.0    2.7  2  AAA_17        AAA domain


Domain annotation for each model (and alignments):
>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  176.1   7.8   1.9e-54   1.1e-51       2     267 ..      28     305 ..      27     335 .. 0.93
   2 !  134.1   8.8   1.1e-41   6.9e-39       3     273 ..     739    1011 ..     737    1012 .. 0.96

  Alignments for each domain:
  == domain 1  score: 176.1 bits;  conditional E-value: 1.9e-54
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSS...TCCHH............HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane   2 iliillailagvlsplfplvlgrildtlldk...gdpet............ealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkk 83 
                   + +i++ai++gv  pl+ +++g++l++++         +            +++n  +ll+++l++aqfil +++ ++++  g rl  rlr +++++
    EEA19500.1  28 LTGIVCAIASGVPFPLIGIIFGQLLNDFNAVtctE---SsdssnssdsgsqHDINSRILLIVYLAIAQFILIYAHLSCWSLYGARLAQRLRERYLQN 121
                   6789*************************996651...3344567788999********************************************** PP

                   HHCSTHHHHHHSCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane  84 ilrqpmsffdtnsvGellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakas 180
                   +lrq+ s+fd+ ++Ge+ srl+ d++++r+g++ek+g+ + s++ fv+++iv+f+    l+  l++++p ++l+s+v ++ ++k++  ++++ a a 
    EEA19500.1 122 LLRQEPSYFDNLPPGEVASRLSADIQTIRSGTSEKVGICLASVSFFVTAYIVAFIKDYILAAQLISLIPAYFLMSFVGSHYIEKYSGLMSDYAATAA 218
                   ************************************************************************************************* PP

                   HHHHHHHHTHHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT..SSTHHHHHHHHHHH CS
  ABC_membrane 181 svaeEslsgirtVkafgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttlvisg..elsvgdlvvflslf 267
                   s+a E+ls+i +V+afg+ ++ ++kf  al++a++ g+kka a g+++g+++++++ ++ la+w G+  + +   + s+g   ++ s f
    EEA19500.1 219 SIASEALSNILVVQAFGANRRLESKFAIALKSAEREGLKKAAAVGIQSGFLYFISYSANGLAFWQGSKRIADAvrDGSPGA--TVGSTF 305
                   *********************************************************************988544555544..333333 PP

  == domain 2  score: 134.1 bits;  conditional E-value: 1.1e-41
                    HHHHHHHHHHHHHHHHHHHHHHHHHHHHSSTCCHH..HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHHHH. CS
  ABC_membrane    3 liillailagvlsplfplvlgrildtlldkgdpet..ealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsffdt. 94  
                    l++l + ++g++    ++++g+ + +l++ ++p++  +  n++ l++++lg+++f++++++ + + +++e+++ + r   f+++++q+++++++ 
    EEA19500.1  739 LALLGSSIVGGAFSGEAVIFGNTVGSLNPCKSPSSidASGNFFGLMFFILGIIEFFANMVSWSGFGWVSEKMVYTARVLSFRSLFEQDLEWHQSk 833 
                    55566666666666899*************99999999********************************************************* PP

                    .SCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane   95 .nsvGellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEsls 188 
                     +++  lls +t+d + l  + g+ +g ++   +++++++i+  ++ w+++lv+l+++pl++    +  ++l k+++++ +a+  +  +  E+++
    EEA19500.1  834 gRTPALLLSYITSDGNALAGLSGSVIGSLLSITINLIAAIILTHIIAWRIALVCLSLVPLLLGAGLMELRVLGKFEERHENAYTTSVDIGVEAIT 928 
                    9********************************************************************************************** PP

                    THHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSTHHHHHHHHHHHHHHHHH CS
  ABC_membrane  189 girtVkafgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttlvisgelsvgdlvvflslfailfga 273 
                     i+t+ ++  ee+ l+ + k+l+ ++k ++++++ ++l +++t++lg++++ala+w+G+ ++i+g+++  +  ++++ f++l+ a
    EEA19500.1  929 SIKTIASLSLEEETLSTYRKSLKGPRKETLRVTLEASLWQAMTYFLGNCVNALAYWWGAKQIIAGNYTQTQ--FLIVVFSLLVSA 1011
                    ***********************************************************************..999999988876 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.8   0.1   2.9e-31   1.7e-28       1     137 []     383     575 ..     383     575 .. 0.86
   2 !  107.6   0.0   1.1e-33   6.9e-31       1     137 []    1104    1256 ..    1104    1256 .. 0.85

  Alignments for each domain:
  == domain 1  score: 99.8 bits;  conditional E-value: 2.9e-31
                 EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.................... CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.................... RF
    ABC_tran   1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren.................... 79 
                 l+ ++l++ +++ +aivG +G+GKSt++ l+++l++ teG+il+dg+d++e++ + lr  ++ ++qep+l +++ + en                    
  EEA19500.1 383 LDGINLSIPPNKHTAIVGLSGSGKSTIAGLVTRLYDATEGQILFDGNDVREINVRDLRGFLSLVQQEPSLLNRS-LLENiahglinssdfrfshlketl 480
                 789***********************************************************************.89999******************* PP

                 ...................................HHHTCHHHHHHHSTTGG.................TTCBGESTTSGGS-HHHHHHHHHHHHHHHT CS
                 ...................................xxxxxxxxxxxxxxxxx.................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  80 ...................................esdeeiekalsklglke.................lkdtvvksspssLSgGqkqrvalarallkk 126
                                                                    +                    t+v+ss++ +SgGqkqrv+laral+k+
  EEA19500.1 481 lsselaelarevregmdlnsaaeqrgadiaeivrlV---------------QhaavladadtfinalqyGYGTIVGSSGRLISGGQKQRVSLARALVKD 564
                 ***999999999999999885554444444443330...............233344444444444444559*************************** PP

                 SSEEEEESTTT CS
                 xxxxxxxxxxx RF
    ABC_tran 127 pkllllDEpta 137
                 p +l++DE+ta
  EEA19500.1 565 PAVLIMDEATA 575
                 *********96 PP

  == domain 2  score: 107.6 bits;  conditional E-value: 1.1e-33
                  EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.......HHHTCHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxx RF
    ABC_tran    1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren.......esdeeiekals 90  
                  l+ +s+++++g+  a+vG++GaGKSt+++l+ +l+ p++G+il+dg+d+++++   +r  i+ +pqe+ lf+++ ++ n        +++ ++++++
  EEA19500.1 1104 LNGLSVDIRPGKFCALVGPSGAGKSTIISLVERLYAPQSGSILIDGADVSKTRDVTFRDTIALVPQESVLFEGS-IEFNiglgakpGQEATLDEIIE 1199
                  6899**********************************************************************.88889***99955555555555 PP

                  HSTTGG..........TTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                  xxxxxx..........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran   91 klglke..........lkdtvvksspssLSgGqkqrvalarallkkpkllllDEpta 137 
                    +l +            +t ++ ++s++SgGqkqr+++aral++kp+ll+lDE t+
  EEA19500.1 1200 ACKLANihdtiaalpnGYQTLCGPNGSQFSGGQKQRLSIARALVRKPRLLILDESTS 1256
                  55555522233332223366666666****************************995 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.6   0.8   5.8e-09   3.5e-06      25     213 ..     394     619 ..     385     624 .. 0.70
   2 ?    5.2   0.1     0.021        13      25      41 ..    1115    1131 ..    1099    1136 .. 0.81
   3 !   18.1   0.0   2.3e-06    0.0014     116     211 ..    1190    1298 ..    1133    1304 .. 0.77

  Alignments for each domain:
  == domain 1  score: 26.6 bits;  conditional E-value: 5.8e-09
                 SEEEEEESTTSSHHHHHHHHHHHCTT.TTTTTTCHCCCCCC--BTTCSSTTEEEEEEEEEETTEESSSSSSCEEEEEEEETTSEEEEEETTEEE-HHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  25 sftaivGpNGSGKsnlldAilFvLGersakklrseklsdlihkskekasvkkaeveitfdnedkklkiekeevsisrrvkrkgeseykingkevtkkev 123
                 ++taivG  GSGKs +   +         + l  ++  ++++  ++ ++++  ++  +++  +       +e s+  r   ++  +  in ++ +++ +
  EEA19500.1 394 KHTAIVGLSGSGKSTIAGLV---------TRLYDATEGQILFDGNDVREINVRDLRGFLSLVQ-------QEPSLLNRSLLENIAHGLINSSDFRFSHL 476
                 46777777777777765444.........2333444444444423333333333333322222.......22333344444444466666666666666 PP

                 HHHHHCTT-STT.........................................................CS-HHHHHHHHHHHHHHHHCCS--SEEEEC CS
                 xxxxxxxxxxxx.........................................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 124 sellesagiske.........................................................lLSgGektLvalaLlfAiqkvkpaplyllD 165
                 +e l s+++ +                                                          l+SgG+k+ v+la       vk  ++ ++D
  EEA19500.1 477 KETLLSSELAELarevregmdlnsaaeqrgadiaeivrlvqhaavladadtfinalqygygtivgssgrLISGGQKQRVSLARA----LVKDPAVLIMD 571
                 666666666555666777777777777777777788888888888888********************9********9988754....567778889** PP

                 TTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC-SCEEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 166 eidaaLDeknvkkvaellkeksknaQfivislreemlekadklvgvtk 213
                 e  a LD +  +++ + +k+  +   +i i++r  +++ ad++v ++k
  EEA19500.1 572 EATASLDSQSEQRIQRAIKNIANGRTMITIAHRLSTITTADNIVVMQK 619
                 *****************************************9987765 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.021
                  SEEEEEESTTSSHHHHH CS
                  xxxxxxxxxxxxxxxxx RF
       SMC_N   25 sftaivGpNGSGKsnll 41  
                  +f a+vGp G+GKs ++
  EEA19500.1 1115 KFCALVGPSGAGKSTII 1131
                  599***********998 PP

  == domain 3  score: 18.1 bits;  conditional E-value: 2.3e-06
                  EEE-HHHHHHHHHCTT-STT.................CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE CS
                  xxxxxxxxxxxxxxxxxxxx.................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  116 kevtkkevsellesagiske.................lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQfivi 195 
                  +e+t  e+ e  + a+i+ +                 ++SgG+k+ +++a       v++  l +lDe  +aLD++  k + + l+++     +i i
  EEA19500.1 1190 QEATLDEIIEACKLANIHDTiaalpngyqtlcgpngsQFSGGQKQRLSIA----RALVRKPRLLILDESTSALDAESEKLLQDGLEKAARGITVIAI 1282
                  444444444444444444447777777777777777799*****976665....4456777799********************************* PP

                  -SSHHHCCC-SCEEEE CS
                  xxxxxxxxxxxxxxxx RF
       SMC_N  196 slreemlekadklvgv 211 
                  ++r ++++kad ++ +
  EEA19500.1 1283 AHRLHTIRKADIIFLI 1298
                  **********987655 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       8.2   4.9e+03      18      34 ..     341     355 ..     334     355 .. 0.70
   2 !   14.0   0.1   5.3e-05     0.031      16      38 ..     387     409 ..     381     421 .. 0.84
   3 !   17.3   0.0   4.8e-06    0.0028      14      42 ..    1106    1134 ..    1102    1145 .. 0.77

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 8.2
      AAA_29  18 eidlkgatlltGpsGsG 34 
                 ++d     l+ G++ sG
  EEA19500.1 341 DMD--RQSLINGTNSSG 355
                 344..457*******99 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 5.3e-05
      AAA_29  16 tieidlkgatlltGpsGsGKSTl 38 
                  ++i ++  t ++G sGsGKST+
  EEA19500.1 387 NLSIPPNKHTAIVGLSGSGKSTI 409
                 567778889*************8 PP

  == domain 3  score: 17.3 bits;  conditional E-value: 4.8e-06
      AAA_29   14 ghtieidlkgatlltGpsGsGKSTllDAi 42  
                  g +++i++  ++ l+GpsG+GKST++  +
  EEA19500.1 1106 GLSVDIRPGKFCALVGPSGAGKSTIISLV 1134
                  56788998889**************9444 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   0.1   9.2e-05     0.055      26     142 ..     395     571 ..     382     601 .. 0.55
   2 !   16.1   0.1   1.8e-05     0.011      25      85 ..    1115    1177 ..    1100    1280 .. 0.53

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 9.2e-05
      AAA_16  26 lvllsGesGvGKsslvrellralekdggiflrgkcdqlesa.......ipysalaqalareellrqlldeaesaeleawrekleeala........... 106
                  + ++G sG+GKs+++  + r + +++g  l   +d  e +       +            +l++q+ + ++ ++le  ++ l  +             
  EEA19500.1 395 HTAIVGLSGSGKSTIAGLVTRLYDATEGQILFDGNDVREINvrdlrgfL------------SLVQQEPSLLNRSLLENIAHGLINSSDfrfshlketll 481
                 6789****************98888887777777777744422232221............33333333322222222222222222233333333333 PP

      AAA_16 107 ..................avpelagaeasrllellkrllallsrder.....................................plvlvlD 142
                                   +++e +ga+   + +l++++++l+   +                                      p vl++D
  EEA19500.1 482 sselaelarevregmdlnSAAEQRGADIAEIVRLVQHAAVLADA-DTfinalqygygtivgssgrlisggqkqrvslaralvkdPAVLIMD 571
                 34445555555555556666666666667777777777766665.4445555555555555555555555555555555555555555555 PP

  == domain 2  score: 16.1 bits;  conditional E-value: 1.8e-05
      AAA_16   25 elvllsGesGvGKsslvrellralekd.ggiflrgkcdqlesaipysa.laqalareellrql 85  
                    + l+G+sG GKs+++  + r +  + g i++ g  ++ ++++++   +a +  ++ l++  
  EEA19500.1 1115 KFCALVGPSGAGKSTIISLVERLYAPQsGSILIDGADVSKTRDVTFRDtIALVPQESVLFEGS 1177
                  7899*****************966666367778888888888877755344444333343333 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.2   0.00021      0.13       6      66 ..     394     455 ..     392     604 .. 0.68
   2 !   12.6   0.1    0.0002      0.12       5      42 ..    1114    1144 ..    1111    1284 .. 0.66

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 0.00021
      AAA_22   6 gilvvtGesGtGKTtllrrlleqldeeakaee.erpevvfvtlpsstsskdllrellralgl 66 
                 ++++++G sG+GK+t +  +++ +d+ + +    + +v ++++  + +  +l ++  + l++
  EEA19500.1 394 KHTAIVGLSGSGKSTIAGLVTRLYDATEGQILfDGNDVREINVRDLRGFLSLVQQEPSLLNR 455
                 689*********************98776666844444444444444333333333333322 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 0.0002
      AAA_22    5 agilvvtGesGtGKTtllrrlleqldeeakaeeerpev 42  
                   ++++++G+sG+GK+t +  + + +         +++ 
  EEA19500.1 1114 GKFCALVGPSGAGKSTIISLVERLYAP-------QSGS 1144
                  6899**************999998853.......3333 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   0.0    0.0017      0.99      19      49 ..     394     424 ..     389     431 .. 0.88
   2 ?   -1.2   0.1       2.4   1.4e+03      81     113 ..     551     590 ..     486     600 .. 0.62
   3 !   13.3   0.0   8.7e-05     0.052      19      47 ..    1115    1153 ..    1111    1285 .. 0.53

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0017
      AAA_30  19 rvavltGpAGtGKttalkalreaweaaggrv 49 
                 + ++++G  G+GK+t+ + ++++++a +g++
  EEA19500.1 394 KHTAIVGLSGSGKSTIAGLVTRLYDATEGQI 424
                 56899*******************9997666 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 2.4
      AAA_30  81 k......grarlepgtllivDEagmv.dtkqlaallkaae 113
                 +      +ra +++  +li DEa    d+++ +++ +a++
  EEA19500.1 551 QkqrvslARALVKDPAVLIMDEATASlDSQSEQRIQRAIK 590
                 1555665555566669999999975436666566555554 PP

  == domain 3  score: 13.3 bits;  conditional E-value: 8.7e-05
      AAA_30   19 rvavltGpAGtGKttalkalreaweaa.g.........g 47  
                  ++++l+Gp G+GK+t+++ ++++++ + g          
  EEA19500.1 1115 KFCALVGPSGAGKSTIISLVERLYAPQsGsilidgadvS 1153
                  5789*******************9999453333333330 PP

>> APS_kinase  Adenylylsulphate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.1   2.2e-05     0.013       7      49 ..     398     439 ..     395     449 .. 0.87
   2 !    7.3   0.0    0.0068         4       7      42 ..    1119    1153 ..    1114    1163 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 2.2e-05
                 EESSTTSSHHHHHHHHHHHHHHTT--EEEEEHHHHTTTTTTT- CS
  APS_kinase   7 ltGlsgsGKstianalekkLvekgisvylLdGdnvRhgLnkdL 49 
                 + GlsgsGKstia  +  +L +     +l dG+ vR+   +dL
  EEA19500.1 398 IVGLSGSGKSTIAGLVT-RLYDATEGQILFDGNDVREINVRDL 439
                 67***********9987.6888889999********9877777 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0068
                  EESSTTSSHHHHHHHHHHHHHHTT--EEEEEHHHHT CS
  APS_kinase    7 ltGlsgsGKstianalekkLvekgisvylLdGdnvR 42  
                  l G sg+GKsti   +e +L + +   +l+dG  v 
  EEA19500.1 1119 LVGPSGAGKSTIISLVE-RLYAPQSGSILIDGADVS 1153
                  78**********99988.677777888899998775 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.8   0.7   7.9e-05     0.047      23      57 ..     393     425 ..     385     618 .. 0.83
   2 !    7.7   0.0    0.0058       3.5      26      59 ..    1117    1148 ..    1106    1149 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 7.9e-05
       DUF87  23 trHlAilgsTGsGKSntvavLleellekkgatili 57 
                 ++H+Ai+g +GsGKS+ ++ L+ +l+ +     ++
  EEA19500.1 393 NKHTAIVGLSGSGKSTIAG-LVTRLY-DATEGQIL 425
                 69*************9887.567777.43334444 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0058
       DUF87   26 lAilgsTGsGKSntvavLleellekkgatililD 59  
                  +A +g +G+GKS+ + +L+e+l+  +++  +++D
  EEA19500.1 1117 CALVGPSGAGKSTII-SLVERLY-APQSGSILID 1148
                  899*********876.69*****.6666555555 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.6   0.0    0.0017         1      21      57 ..     398     434 ..     391     462 .. 0.89
   2 !   10.3   0.0    0.0005       0.3      20      53 ..    1118    1151 ..    1110    1159 .. 0.88

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0017
  Zeta_toxin  21 lgGqpGAGKselaellkdelerqgnvvrldpDdlRel 57 
                 ++G +G+GKs++a l+++  +++++ + +d+ d+Re 
  EEA19500.1 398 IVGLSGSGKSTIAGLVTRLYDATEGQILFDGNDVREI 434
                 78999******************************97 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.0005
  Zeta_toxin   20 llgGqpGAGKselaellkdelerqgnvvrldpDd 53  
                   l+G +GAGKs++++l+++  ++q++ + +d+ d
  EEA19500.1 1118 ALVGPSGAGKSTIISLVERLYAPQSGSILIDGAD 1151
                  689***********************99999765 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.1     0.018        11      99     117 ..     393     411 ..     381     428 .. 0.82
   2 !   13.2   0.0    0.0001      0.06      93     119 ..    1107    1134 ..    1081    1154 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.018
                  TSEEEEECSTTSSHHHHHH CS
  RsgA_GTPase  99 dktsvlvGqSGvGKStLin 117
                  +k +++vG SG GKSt+  
   EEA19500.1 393 NKHTAIVGLSGSGKSTIAG 411
                  58899***********865 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 0.0001
                   HHHHCTT.SEEEEECSTTSSHHHHHHHH CS
  RsgA_GTPase   93 lkellkd.ktsvlvGqSGvGKStLinal 119 
                   l+  ++  k+++lvG+SG+GKSt+i  +
   EEA19500.1 1107 LSVDIRPgKFCALVGPSGAGKSTIISLV 1134
                   55556655999*************9765 PP

>> DUF3987  Protein of unknown function (DUF3987)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.2   0.0   0.00011     0.068      32      65 ..     389     422 ..     374     433 .. 0.84
   2 ?    4.9   0.0     0.019        11      33      59 ..    1111    1137 ..    1094    1144 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00011
     DUF3987  32 teplnLytlvvapsGerKSpvdklvlrpleeiea 65 
                   p+n +t++v+ sG++KS+++ lv+r+  + e 
  EEA19500.1 389 SIPPNKHTAIVGLSGSGKSTIAGLVTRLYDATEG 422
                 679************************9988775 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.019
     DUF3987   33 eplnLytlvvapsGerKSpvdklvlrp 59  
                    +  +++ v+psG +KS++ +lv r+
  EEA19500.1 1111 IRPGKFCALVGPSGAGKSTIISLVERL 1137
                  566779***************998776 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.1   0.0    0.0048       2.9       4      17 ..     398     411 ..     396     468 .. 0.84
   2 !    7.5   0.0     0.007       4.2       4      18 ..    1119    1133 ..    1117    1173 .. 0.71

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0048
      AAA_33   4 lvGlpGsGKstlae 17 
                 +vGl+GsGKst a 
  EEA19500.1 398 IVGLSGSGKSTIAG 411
                 79*********875 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.007
      AAA_33    4 lvGlpGsGKstlaer 18  
                  lvG++G+GKst +  
  EEA19500.1 1119 LVGPSGAGKSTIISL 1133
                  79*********7543 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   0.0    0.0066       3.9       3      22 ..     398     417 ..     397     464 .. 0.77
   2 !    7.9   0.0    0.0069       4.1       3      30 ..    1119    1148 ..    1118    1176 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0066
      AAA_18   3 ltGtpGvGKttlakeLskrl 22 
                 + G +G+GK+t+a  + ++ 
  EEA19500.1 398 IVGLSGSGKSTIAGLVTRLY 417
                 89***********9987763 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0069
      AAA_18    3 ltGtpGvGKttlakeLskrlgf....gvnlrd 30  
                  l G++G+GK+t+   ++++  +    g +l+d
  EEA19500.1 1119 LVGPSGAGKSTIISLVERL--YapqsGSILID 1148
                  89***********999776..33456555555 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0     0.086        51      30      50 ..     390     410 ..     375     433 .. 0.91
   2 ?   -2.5   0.0       5.3   3.2e+03     133     171 ..     557     591 ..     498     601 .. 0.62
   3 !    9.5   0.0    0.0011      0.68      22      50 ..    1104    1131 ..    1082    1143 .. 0.77
   4 ?   -0.3   0.0       1.1   6.5e+02     134     160 ..    1239    1263 ..    1230    1289 .. 0.63

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.086
      AAA_25  30 lpagelallaGapgtGKttla 50 
                 +p ++ ++++G +g+GK+t+a
  EEA19500.1 390 IPPNKHTAIVGLSGSGKSTIA 410
                 7888999************97 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 5.3
      AAA_25 133 leaaieevegvrlvviDplsralggdensnsdvgalvea 171
                 l++a+ +  ++++++ D  ++ l+   +s+  +++++++
  EEA19500.1 557 LARALVK--DPAVLIMDEATASLDS--QSEQRIQRAIKN 591
                 5555555..6888888877766554..333445555554 PP

  == domain 3  score: 9.5 bits;  conditional E-value: 0.0011
      AAA_25   22 rrwlvkgllpagelallaGapgtGKttla 50  
                  ++ l  +++  g++++l+G++g+GK+t+ 
  EEA19500.1 1104 LNGLSVDIR-PGKFCALVGPSGAGKSTII 1131
                  555555665.5****************86 PP

  == domain 4  score: -0.3 bits;  conditional E-value: 1.1
      AAA_25  134 eaaieevegvrlvviDplsralggden 160 
                  ++a+ +  ++rl+++D  ++al+++++
  EEA19500.1 1239 ARALVR--KPRLLILDESTSALDAESE 1263
                  555555..59*******9999998555 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0      0.54   3.2e+02       3      35 ..     398     440 ..     396     465 .. 0.69
   2 ?    4.3   0.1     0.085        51      46      96 ..     553     596 ..     499     617 .. 0.69
   3 ?    4.5   0.0     0.075        45       3      19 ..    1119    1135 ..    1117    1187 .. 0.84
   4 ?    2.1   0.0      0.41   2.4e+02      53     118 ..    1239    1292 ..    1190    1298 .. 0.79

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.54
                 EESSTTSSHHHHHHHHHHHH..........THEEEEEETTTCS CS
         AAA   3 lyGppGtGKTllakavakel..........gvefleisgsell 35 
                 ++G  G GK+++a  v +            g ++ ei++ +l+
  EEA19500.1 398 IVGLSGSGKSTIAGLVTRLYdategqilfdGNDVREINVRDLR 440
                 68999********999887622332222333446666665555 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.085
                 HHHHHHHHHHTS.....TSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHT CS
         AAA  46 irelfkeakeka.....kpsilfiDEidalaksrsgseseeeervvnqLlteldgv 96 
                  r  +      a     +p +l++DE+ a   s+      +e+r++ ++ +  +g 
  EEA19500.1 553 QRVSL------AralvkDPAVLIMDEATASLDSQ------SEQRIQRAIKNIANGR 596
                 23333......23334559**********99999......5666666665555554 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.075
                  EESSTTSSHHHHHHHHH CS
         AAA    3 lyGppGtGKTllakava 19  
                  l+Gp G GK+++++ v 
  EEA19500.1 1119 LVGPSGAGKSTIISLVE 1135
                  89**********99875 PP

  == domain 4  score: 2.1 bits;  conditional E-value: 0.41
                  HHHTS.TSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTSSSTEEEEEEESSGGGSTHH CS
         AAA   53 akeka.kpsilfiDEidalaksrsgseseeeervvnqLlteldgvkkkeskvivigatnrpdkldpa 118 
                  a++   kp  l++DE  +   ++            ++Ll+  dg++k  + ++vi++++r +++ +a
  EEA19500.1 1239 ARALVrKPRLLILDESTSALDAE-----------SEKLLQ--DGLEKAARGITVIAIAHRLHTIRKA 1292
                  33333457888888888888888...........677776..6666666789********9999987 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.1     0.054        32       2      26 ..     396     421 ..     396     475 .. 0.78
   2 !   11.1   0.0   0.00043      0.25       3      69 ..    1118    1191 ..    1116    1217 .. 0.69

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.054
      AAA_21   2 nvliGpNgsGKSnLLdaldllarl.d 26 
                 ++++G  gsGKS++  +   l ++  
  EEA19500.1 396 TAIVGLSGSGKSTIAGLVTRLYDAtE 421
                 79************988888877652 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00043
      AAA_21    3 vliGpNgsGKSnLLdaldllarl.......drdvegltdelsggggirkipslldlydpeipfefeieeflsqg 69  
                  +l+Gp g+GKS+++ + + l          d+   + t + + + +i+ +p ++ l + +i+f++++  ++ q+
  EEA19500.1 1118 ALVGPSGAGKSTIISLVERLYAPqsgsiliDGADVSKTRDVTFRDTIALVPQESVLFEGSIEFNIGLGAKPGQE 1191
                  79****************99766777666655555555555555666666666666666666666665555555 PP

>> ABC_ATPase  Predicted ATPase of the ABC class
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0       5.7   3.4e+03     243     260 ..     392     409 ..     368     418 .. 0.74
   2 ?    1.9   0.1      0.13        77     300     352 ..     523     576 ..     510     628 .. 0.83
   3 !   10.6   0.0    0.0003      0.18     300     354 ..    1204    1259 ..    1198    1301 .. 0.81

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 5.7
                 -SSEEEEEE-TTSSHHHH CS
  ABC_ATPase 243 pkGvtlIvGggfhGKsTL 260
                 p++ t+IvG    GKsT+
  EEA19500.1 392 PNKHTAIVGLSGSGKSTI 409
                 455899**********96 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.13
                 E--TTTB---CCC--ST.TEEESS--HHHHHHHHHHHHHHTT-SEEEEEGGGS- CS
  ABC_ATPase 300 vDispFinnLPegkdtt.kfstedASGStsqAanimealeagakllLiDEDtsA 352
                 +D  +Fin+L +g  t   +s +  SG   q +++++al  +  +l++DE t+ 
  EEA19500.1 523 ADADTFINALQYGYGTIvGSSGRLISGGQKQRVSLARALVKDPAVLIMDEATAS 576
                 58899*********99977888899*************************9875 PP

  == domain 3  score: 10.6 bits;  conditional E-value: 0.0003
                  E--TTTB---CCC--STTE.EESS--HHHHHHHHHHHHHHTT-SEEEEEGGGS-HH CS
  ABC_ATPase  300 vDispFinnLPegkdttkf.stedASGStsqAanimealeagakllLiDEDtsAtN 354 
                  ++i   i +LP+g +t +    ++ SG   q  +i++al ++ +ll++DE tsA  
  EEA19500.1 1204 ANIHDTIAALPNGYQTLCGpNGSQFSGGQKQRLSIARALVRKPRLLILDESTSALD 1259
                  689999***********65156789*****************************65 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.6   0.3    0.0041       2.4      19      35 ..     393     409 ..     381     415 .. 0.86
   2 !    9.4   0.0    0.0022       1.3      21      36 ..    1116    1131 ..    1100    1135 .. 0.78

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0041
      AAA_23  19 kgltlItGpNGaGKTTi 35 
                 ++ t+I+G  G+GK+Ti
  EEA19500.1 393 NKHTAIVGLSGSGKSTI 409
                 5789************9 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.0022
      AAA_23   21 ltlItGpNGaGKTTil 36  
                  + +++Gp GaGK+Ti+
  EEA19500.1 1116 FCALVGPSGAGKSTII 1131
                  5579***********8 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.0     0.025        15       2      34 ..     396     429 ..     395     494 .. 0.80
   2 !    7.6   0.0    0.0063       3.8       2      19 ..    1117    1134 ..    1116    1177 .. 0.73

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.025
                 EEEEESTTSSHHHHHHHHHTS.TEEESSSTTSSS CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltge.kaivsdkpgtTr 34 
                  aivG + +GKSt+    t+   a  +++ +   
  EEA19500.1 396 TAIVGLSGSGKSTIAGLVTRLyDATEGQILFDGN 429
                 59***********987766654555555555555 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0063
                  EEEEESTTSSHHHHHHHH CS
    MMR_HSR1    2 vaivGrpNvGKStLinal 19  
                  +a+vG + +GKSt+i+  
  EEA19500.1 1117 CALVGPSGAGKSTIISLV 1134
                  69***********99754 PP

>> SbcCD_C  Putative exonuclease SbcCD, C subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0     0.027        16      62      88 ..     563     589 ..     545     591 .. 0.81
   2 ?    6.0   0.2     0.023        14      61      82 ..    1243    1264 ..    1214    1272 .. 0.79

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.027
     SbcCD_C  62 palrlvfLDEAFsklDeesiatllell 88 
                 ++++++++DEA ++lD++s +++ +++
  EEA19500.1 563 KDPAVLIMDEATASLDSQSEQRIQRAI 589
                 56899************9988876665 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.023
     SbcCD_C   61 epalrlvfLDEAFsklDeesia 82  
                   +++rl++LDE  s lD+es +
  EEA19500.1 1243 VRKPRLLILDESTSALDAESEK 1264
                  4579*************99865 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       5.1   3.1e+03      32      75 ..     338     387 ..     325     389 .. 0.76
   2 ?    4.5   0.0     0.055        33       4      24 ..     398     418 ..     395     465 .. 0.86
   3 ?    7.1   0.0    0.0082       4.9       4      26 ..    1119    1143 ..    1117    1202 .. 0.77

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 5.1
                 --TT--HHHHH--B--................--------G-SEEEEESGG CS
       AAA_5  32 ltrdtteedlkgrreik.......ngttslvdsplvraaregeilvlDEve 75 
                 l++d+ ++ l+ +++ +       +g+ ++++ +++  a ++e++vlD+++
  EEA19500.1 338 LREDMDRQSLINGTNSSglrllkaQGGFEFKNVSFKYPA-RPEVTVLDGIN 387
                 567777777887777667777777777777777777444.6899****998 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.055
                 EE--SSSSHHHHHHHGGGGBS CS
       AAA_5   4 LvGppGtgKselaerlaaaln 24 
                 +vG +G+gKs++a  + +++ 
  EEA19500.1 398 IVGLSGSGKSTIAGLVTRLYD 418
                 79************9999983 PP

  == domain 3  score: 7.1 bits;  conditional E-value: 0.0082
                  EE--SSSSHHHHHHHGGGGB..S-- CS
       AAA_5    4 LvGppGtgKselaerlaaal..nre 26  
                  LvGp+G gKs+++  + +++  ++ 
  EEA19500.1 1119 LVGPSGAGKSTIISLVERLYapQSG 1143
                  9**************9999975444 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00044      0.27      47     150 ..     431     593 ..     386     611 .. 0.59
   2 ?    0.7   0.0      0.67     4e+02      85     140 ..    1204    1264 ..    1109    1277 .. 0.49

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00044
                 S.............................................-EEEEEESSHHHHHHHHHHH..HHHTTTST......SEEEEEET....TSSHH CS
                 x.............................................xxxxxxxxxxxxxxxxxxxx..xxxxxxxx......xxxxxxxx....xxxxx RF
        DEAD  47 g.............................................pkalivePtreLaeqtlnnl..kkfkkyid......lrvlliig....gvaar 88 
                                                               + +l+ + + eLa+++ + +  ++  ++ +      +    +++      +a+
  EEA19500.1 431 VreinvrdlrgflslvqqepsllnrslleniahglinssdfrfshlKETLLSSELAELAREVREGMdlNSAAEQRGadiaeiV---RLVQhaavLADAD 526
                 05555555555666666666666666666666666666666666666666666666666666554421222222112221221...1111111112334 PP

                 HHHHHHHTTCSEEEEEHHHHHHHHHCTSSH.....CTTEEEEEEETHHHHHHTTTHHHHHHHHHHSH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  89 dqlskldngvdivvgtpgrlddllstgkln.....lsqvrflVlDEadrlldqgfsdfinrilnqlp 150
                   +++l+ g+  +vg  grl++  ++++++     +++  +l++DEa   ld++ ++ i+r +++++
  EEA19500.1 527 TFINALQYGYGTIVGSSGRLISGGQKQRVSlaralVKDPAVLIMDEATASLDSQSEQRIQRAIKNIA 593
                 445666788999**********886666665567688889*********************999995 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.67
                  SSHHHHHHHHHTTCSEEEEEHHHHHHHHHCTSSH.....CTTEEEEEEETHHHHHHTTTHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   85 vaardqlskldngvdivvgtpgrlddllstgkln.....lsqvrflVlDEadrlldqgfsd 140 
                   + +d +++l ng++ + g  g  ++  ++++l+     +++ r+l+lDE    ld + ++
  EEA19500.1 1204 ANIHDTIAALPNGYQTLCGPNGSQFSGGQKQRLSiaralVRKPRLLILDESTSALDAESEK 1264
                  3344444444455555555555554444445544444446666788888877777765555 PP

>> SRP54  SRP54-type protein, GTPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   0.0     0.021        13       4      36 ..     396     428 ..     393     435 .. 0.82
   2 ?    6.2   0.0     0.012       7.2       4      39 ..    1117    1152 ..    1115    1157 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.021
                 EEEEESTTSSHHHHHHHHHHHHHHTTS-EEEEE CS
       SRP54   4 illvGlqGaGKTttlaKLaallkkegkkvllva 36 
                 +++vGl G+GK t ++ + +l+ + + ++l+  
  EEA19500.1 396 TAIVGLSGSGKSTIAGLVTRLYDATEGQILFDG 428
                 689**********99999999988877777655 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.012
                  EEEEESTTSSHHHHHHHHHHHHHHTTS-EEEEEEST CS
       SRP54    4 illvGlqGaGKTttlaKLaallkkegkkvllvaaDt 39  
                  ++lvG+ GaGK t ++ + +l+  +  ++l+  aD+
  EEA19500.1 1117 CALVGPSGAGKSTIISLVERLYAPQSGSILIDGADV 1152
                  689*******************99999999999986 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.0     0.012         7      24      49 ..     397     422 ..     391     434 .. 0.84
   2 ?    4.5   0.0     0.029        17      18      40 ..    1113    1134 ..    1100    1139 .. 0.76

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.012
                 EEEESTTSSHHHHHHHHCCSHCCCCC CS
      NB-ARC  24 alvGmgGvGKttlakqilnksdeveg 49 
                 a+vG  G+GK+t+a  + + +d +eg
  EEA19500.1 397 AIVGLSGSGKSTIAGLVTRLYDATEG 422
                 79************999888887776 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.029
                  SCSEEEEEEESTTSSHHHHHHHH CS
      NB-ARC   18 lqslvvalvGmgGvGKttlakqi 40  
                  ++  + alvG  G GK+t+++ +
  EEA19500.1 1113 PG-KFCALVGPSGAGKSTIISLV 1134
                  55.6889************9755 PP

>> KdpD  Osmosensitive K+ channel His kinase sensor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0      0.11        67      67     107 ..     549     587 ..     538     615 .. 0.78
   2 ?    7.7   0.0    0.0037       2.2      63     121 ..    1226    1282 ..    1196    1298 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.11
        KdpD  67 gkeleeldldailarkpevvlvDelahtnapgsrhekryqd 107
                 g + ++++l  +l ++p+v+++De   +   +s+ e+r q 
  EEA19500.1 549 GGQKQRVSLARALVKDPAVLIMDEATASL--DSQSEQRIQR 587
                 66778999****************87775..5555555554 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0037
        KdpD   63 veykgkeleeldldailarkpevvlvDelahtnapgsrhekryqdveelLeagidVitt 121 
                   + +g + ++l++  +l rkp+++++De   t a +++ ek  qd  e  ++gi Vi+ 
  EEA19500.1 1226 SQFSGGQKQRLSIARALVRKPRLLILDES--TSALDAESEKLLQDGLEKAARGITVIAI 1282
                  567788999*******************6..566799999*****99999999999975 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0     0.033        20      28      55 ..     388     415 ..     380     426 .. 0.80
   2 ?    5.6   0.0     0.017        10      33      52 ..    1114    1133 ..    1102    1146 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.033
       AAA_7  28 lllknkkpvllvGptGtGKtviikdllk 55 
                 l +  +k++ +vG +G+GK++i+  +++
  EEA19500.1 388 LSIPPNKHTAIVGLSGSGKSTIAGLVTR 415
                 5667799**************9876655 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.017
       AAA_7   33 kkpvllvGptGtGKtviikd 52  
                  +k + lvGp+G GK++ii+ 
  EEA19500.1 1114 GKFCALVGPSGAGKSTIISL 1133
                  567889***********975 PP

>> Cad  Cadmium resistance transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.2      0.31   1.9e+02      29      68 ..     156     192 ..     142     202 .. 0.70
   2 ?   10.8   0.8   0.00057      0.34      29      78 ..     854     907 ..     838     939 .. 0.74

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.31
         Cad  29 ylGqylGsvalvlvsllfafvlnyvpeewilGllGlipiy 68 
                  +G  l sv++ + + ++af+ +y+   ++   + lip y
  EEA19500.1 156 KVGICLASVSFFVTAYIVAFIKDYILAAQL---ISLIPAY 192
                 567777888888888888888888776665...5566665 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00057
         Cad  29 ylGqylGsvalvlvsllfafvlnyvpe.ewilGllGlipiylG...ikvlllGd 78 
                   G ++Gs + +++ l++a++l ++   +  l  l l+p++lG   + + +lG+
  EEA19500.1 854 LSGSVIGSLLSITINLIAAIILTHIIAwRIALVCLSLVPLLLGaglMELRVLGK 907
                 56999*****************9886614457789*******933223445665 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0      0.17     1e+02       4      20 ..     395     411 ..     393     448 .. 0.85
   2 ?    6.2   0.0     0.013       7.7       5      22 ..    1117    1134 ..    1114    1220 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.17
      AAA_24   4 kiliyGpsgiGKTtlak 20 
                   +i+G sg+GK+t+a 
  EEA19500.1 395 HTAIVGLSGSGKSTIAG 411
                 678***********985 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.013
      AAA_24    5 iliyGpsgiGKTtlakel 22  
                  ++++Gpsg+GK+t+++  
  EEA19500.1 1117 CALVGPSGAGKSTIISLV 1134
                  689**********99876 PP

>> AAA_17  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0     0.063        38       1      19 [.     399     417 ..     399     463 .. 0.88
   2 ?    4.7   0.0     0.063        37       1      19 [.    1120    1137 ..    1120    1170 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.063
                 EE-TTSSHHHHHHHHHHHH CS
      AAA_17   1 lGgPGsGKgtqceklveky 19 
                 +G+ GsGK+t++  + + y
  EEA19500.1 399 VGLSGSGKSTIAGLVTRLY 417
                 79*********96666555 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.063
                  EE-TTSSHHHHHHHHHHHH CS
      AAA_17    1 lGgPGsGKgtqceklveky 19  
                  +G+ G+GK+t++  lve++
  EEA19500.1 1120 VGPSGAGKSTII-SLVERL 1137
                  79**********.666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1330 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       975  (0.0543812); expected 358.6 (0.02)
Passed bias filter:                      613  (0.0341904); expected 358.6 (0.02)
Passed Vit filter:                        96  (0.00535445); expected 17.9 (0.001)
Passed Fwd filter:                        31  (0.00172904); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              30  [number of targets reported over threshold]
# CPU time: 1.17u 0.38s 00:00:01.54 Elapsed: 00:00:00.57
# Mc/sec: 7080.92
//
Query:       EEA19501.1  [L=2103]
Description: nonribosomal peptide synthase SidD [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      5e-68  229.6   0.1    7.3e-64  215.9   0.0    2.4  2  AMP-binding    AMP-binding enzyme
    8.7e-67  225.8   0.0    4.4e-36  124.5   0.0    2.6  2  Condensation   Condensation domain
    1.7e-28   98.8   0.3    4.4e-13   49.4   0.1    3.3  2  PP-binding     Phosphopantetheine attachment site
    0.00019   22.3   0.0       0.12   13.4   0.0    3.3  3  AMP-binding_C  AMP-binding enzyme C-terminal domain
  ------ inclusion threshold ------
       0.12   12.5   0.2       0.36   10.9   0.0    1.8  2  Symplekin_C    Symplekin tight junction protein C terminal


Domain annotation for each model (and alignments):
>> AMP-binding  AMP-binding enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  215.9   0.0     2e-67   7.3e-64       3     423 .]     241     643 ..     239     643 .. 0.83
   2 !   11.4   0.0   2.4e-05     0.087     395     421 ..    1387    1413 ..    1376    1415 .. 0.88

  Alignments for each domain:
  == domain 1  score: 215.9 bits;  conditional E-value: 2e-67
                  HHHHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEEEE CS
  AMP-binding   3 eqaaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakvlia 100
                  e+a  tp+k+a+ +   + tlTY ++d+ ++ lA+ L+ +Gv+  d   ++ ++s   +va+la++k+Ga+ v+++p+ + ++l+ + ++++ak+++ 
   EEA19501.1 241 ERAGATPEKTAIDS--WDGTLTYDQVDKYSTFLAKTLKDIGVELNDFLPLCFEKSKWTIVAVLAAMKVGATFVMMDPSIPLARLQNMRKQVGAKTML- 335
                  78899*******65..7889******************99*********************************************************. PP

                  TCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHHHHCSC CS
  AMP-binding 101 tvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkletrfk 198
                    ++++    ++  a+  +  + ++++       e++ ++ +s+e     +e + + +d+l+y+i+TSG+TG+PKGV +sh+ +++++      +  +
   EEA19501.1 336 -SSRKQ----HDFSASIISGGKLLIVE-------EDMFASVNSAEL---VPELPIVPSDTLMYLIFTSGSTGTPKGVKISHGTYTSSAIPR--AKAVG 416
                  .33222....12222222233333444.......334444434433...235557999***********************9999986662..33456 PP

                  CTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEEEESS-EB CS
  AMP-binding 199 lkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvllggepls 296
                   +ed++v+ ++++a+++++  ++ll+l++G+++++++ +++++   + ++i+k +v++   +P+v++ l  +             sl  + lgge+ s
   EEA19501.1 417 YTEDSRVFDFASYAFDVSI-DSMLLTLANGGCLCIPSDEDRMN--DINGVIRKMRVNYAGITPSVARILEPD----------VIASLSGLGLGGEAAS 501
                  679***************7.***************99888833..4779****************9988433..........3446666667999988 PP

                  HHHHHHHHHHHTCEEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBE.ETTSEEEEEEEETTS-SEBTT-HHHHHHHEEE.. CS
  AMP-binding 297 pellrffralfgeevlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeetgepv.pdgeeGellvrgpgvmkgYlkkpeataeafds.. 391
                  +  ++ + + +  +++ gYG+ E+t+ +tv+      +   s+G+   g+ + +vD+++ e + p g +Gellv gp v +gYl++ e+ta af++  
   EEA19501.1 502 ARDVTIWGRET--RIIIGYGPCECTIGCTVNSSAATGRDYISIGTG-NGAAIWVVDPNDHEKLmPVGAVGELLVEGPIVGQGYLNDLEKTAAAFIEdp 596
                  88887777775..599************884444444456689999.899*****9987655549******************************889 PP

                  ............T.CCEEEEEEEEEEETTSE..EEEEEECCCEEEET CS
  AMP-binding 392 ............e.grwlrTGDlgrldedGy..leivgRkkdliklr 423
                                gr+++TGDlg++d+dG+  + + gRk+ ++klr
   EEA19501.1 597 qwlitghkdyagRrGRLYKTGDLGKYDPDGSggIIFAGRKDTQVKLR 643
                  9*********973578************97544************96 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 2.4e-05
                   EEEEEEEEEEETTSEEEEEEECCCEEE CS
  AMP-binding  395 wlrTGDlgrldedGyleivgRkkdlik 421 
                      TGD++ l++dG+l ++gRk d++ 
   EEA19501.1 1387 VQATGDIVQLQQDGSLIFLGRKEDIVP 1413
                   668*********************985 PP

>> Condensation  Condensation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  124.5   0.0   1.2e-39   4.4e-36       2     456 ..     886    1299 ..     885    1300 .. 0.83
   2 !   98.5   0.0   9.7e-32   3.5e-28       2     366 ..    1692    2024 ..    1691    2071 .. 0.82

  Alignments for each domain:
  == domain 1  score: 124.5 bits;  conditional E-value: 1.2e-39
                    EEEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T..TSSSHH CS
  Condensation    2 qdeyplspaQkrmwflekleeessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvileerevelevleisdleeseee 96  
                    +d+yp +p Q+ +++++  +   + y+ q v  +  ++++e  +ka++ ++ + ++LRt++ + ++    Q++l+e  +++        +es+  
    EEA19501.1  886 EDIYPCTPTQESLFTFSLKS--IKPYIAQRVACIPDSINIESWKKAWEDVVLQSPILRTRLAQLQERGLQQIVLKE-GISW--------NEST-- 967 
                    799*******9999998766..7889999999*****************************876566666666654.4555........3333.. PP

                    HHHHHHHHHHHTC--SCCCS-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--.HHHHHHHHHHHHCSHH CS
  Condensation   97 eaieefaqkdlqepfdLekgpLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktp.Ykdyaeweqqyleskd 190 
                     ++ +++++d++e +dL +       + ++++ + +++++vHH++ DG+S +i+l++ +++     +g+ ++ ++    + +y+   ++      
    EEA19501.1  968 -DLAQYLTDDKRERMDLGQRLARYTIINDHNDGKRYMVWTVHHVLYDGWSEPIILKKVSDAL----QGQGIQFQTQMReFVKYVRDTNE------ 1051
                    .48899***********9976666666689999***************************99....77777775444347778877444...... PP

                    HHHHHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEESSTTCS CS
  Condensation  191 lekeeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisgResei 285 
                      + ++YW+  l+      ++ ++ +r+++r+f   +    +++++     +++k ++ t+ ++   a++l+ s+yt+++d+v+g +  gR  + 
    EEA19501.1 1052 -VEMQEYWRRELKD-----AVGPQFPRLPSRDFV-PTPNAMVEHHI---SIETQKGSQFTMATLIRGAWALVASQYTRSSDVVFGETLTGRDIAL 1136
                    .45667***99998.....566666777888887.44444443333...346788999***********************************99 PP

                    TCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEECCCCSEEECE CS
  Condensation  286 kdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeeesqlselklsv 380 
                     ++e++vG  + t+P+ri v +a +   +++++++ +++   +q  + ++++k ++  + + +    ++ ++++     e e + ++l    l+ 
    EEA19501.1 1137 AEVENIVGPLIATVPVRIYVHRASSVEVYLQSIQQSMMSRTCYQHLGMQNIRKVSRDAQHACEA---STGLVIQP----EPEYTGNELG--FLQG 1222
                    9**************************************************9999988875444...56666666....3333333333..3334 PP

                    E....E.....SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTTSBCCC-----HHHHHHH CS
  Condensation  381 ssve.aeeeskydlsleasetngkltikieYntslFdeetierflerlkelleqviehpeqklselkllsdaekekL 456 
                    ++v  a +  +y l +   +++g++++  ++ +sl + ++++r+l++l+ +  q+i++++ kl +++ l++ae +++
    EEA19501.1 1223 DVVReALHFNPYPLMIACGIRKGGFRVCANFDSSLIEVSQMQRILQQLEVACVQLIKNTSRKLGDISCLPEAELNQI 1299
                    4566688999**************************************************************98776 PP

  == domain 2  score: 98.5 bits;  conditional E-value: 9.7e-32
                    EEEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T..TSSSHH CS
  Condensation    2 qdeyplspaQkrmwflekleeessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvileerevelevleisdleeseee 96  
                    qd++p+++ Q   + +    + ++  ++ ++l++++ +d+  l +a ++l++ hd+LRtvf+e+     +Qv+l++  +++   + ++ +++  e
    EEA19501.1 1692 QDVAPVTDSQ--ALDIRGTIQTPRTSIQYTMLYFDKDIDQAKLLNACNTLVKSHDILRTVFIEH-GSSYFQVVLDNLATTV---DERK-TDQGLE 1779
                    7889999999..89999999999999***********************************988.**************99...4442.566667 PP

                    HHHHHHHHHHHTC--SCCCS-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHHH CS
  Condensation   97 eaieefaqkdlqepfdLekgpLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskdl 191 
                    e + ++ ++d+ ++++L  +p +++  ++ ae ++ l+l++ H   DGvSl+ llrdl  +Y    +g+++ +  + ++++y+ + ++   +  +
    EEA19501.1 1780 EYATNLCTDDITSQLELG-CPFMKFLHIEGAEGKHCLILRLSHAQYDGVSLPRLLRDLEMFY----NGNNVTD--FMSFSRYVAHIRD---ESVQ 1864
                    889999999999999994.7******************************************....9999777..66699**999555...5555 PP

                    HHHHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEESSTTCST CS
  Condensation  192 ekeeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisgReseik 286 
                     k+ +YW+ +l+g   ++++++ k +pa  ++k + +  k+ +++          +++t  ++l a ++l+L +  +++d+ +g ++sgR     
    EEA19501.1 1865 SKAIDYWKPLLSG--SSISVLEGKSQPA--TTK-SIFHTKIVDDVPL------PLEDITTASLLIAGWSLVLARRLKTTDVTFGGVTSGRIVDLA 1948
                    6999*********..7888888733333..333.2444444344433......45678999*******************************999 PP

                    CHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCC CS
  Condensation  287 diermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqes 366 
                    d+e++vG      P r++ +++ t  +l+k v+++  ++  ++  ++e++ k + ++ + s +     ++ f ++  +++
    EEA19501.1 1949 DVENVVGPCYQFTPTRVRFQNNWTGMDLLKFVQKQSAESAAYDFLGFEKISKACSQWSSPSSK----EQLFFDSLVHHQD 2024
                    *******************************************************99985433....5555555443333 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.9   0.0   1.4e-15   5.2e-12       1      65 [.     781     844 ..     781     846 .. 0.97
   2 !   49.4   0.1   1.2e-16   4.4e-13       3      64 ..    1584    1644 ..    1582    1647 .. 0.94

  Alignments for each domain:
  == domain 1  score: 45.9 bits;  conditional E-value: 1.4e-15
  PP-binding   1 eklrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaa 65 
                 ++lr+++ + l+ ++e+i +++++f lG+DSl+a++l++  +e+ ++e++++  f+hptla++a 
  EEA19501.1 781 QRLRQAWGQTLKADPESIRLEDNFFVLGGDSLAAMRLVSVCREQ-NLELTVANTFDHPTLAAMAS 844
                 589*****************************************.*****************986 PP

  == domain 2  score: 49.4 bits;  conditional E-value: 1.2e-16
  PP-binding    3 lrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaela 64  
                  lr+++a++lg++ e id+d+++f lG+DS+la++l++ l+++ g  ++++d+f+h  l++ a
  EEA19501.1 1584 LRAAWAKILGIDSEKIDVDDNFFRLGGDSVLAMKLISNLRAR-GHGLTVADIFQHMRLGDAA 1644
                  9*****************************************.************9998866 PP

>> AMP-binding_C  AMP-binding enzyme C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.0     0.015        55      27      76 .]     680     746 ..     653     746 .. 0.76
   2 ?   -2.2   0.0       2.4   8.5e+03      42      61 ..    1420    1438 ..    1411    1443 .. 0.53
   3 !   13.4   0.0   3.2e-05      0.12      20      72 ..    1485    1536 ..    1482    1538 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.015
                    ---EEEEEE--..-...---......HHHHHHHHH.......HHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C  27 ealvafVvlkd..g...sea......leeeLkahv.......rkelgpyavpkkvvfvdelpktrsGK 76 
                     +lvafV  ++  g   +        l+eeL+  +       +k l+ y+ p + + v+ +p   sGK
     EEA19501.1 680 ATLVAFVSSQStnGagsT-TdiesitLPEELQTALsqanteiTKVLPRYMLPTAYIPVNHIPVLISGK 746
                    459999997422234432.1467799999999999655555555************9*9999999988 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 2.4
                     HHHHHHHHHHHHT-TTTS-S CS
  AMP-binding_C   42 leeeLkahvrkelgpyavpk 61  
                       +eL++h+rk l++   p 
     EEA19501.1 1420 NVAELESHLRKYLPSA-IPA 1438
                     3467777777777663.443 PP

  == domain 3  score: 13.4 bits;  conditional E-value: 3.2e-05
                     ----TTS---EEEEEE------HHHHHHHHHHHHT-TTTS-SEEEE-S---B- CS
  AMP-binding_C   20 vpdevkGealvafVvlkdgsealeeeLkahvrkelgpyavpkkvvfvdelpkt 72  
                     v+d  + e+ ++  v+k   +a  ++ ++++r+ l++y+vp +  +vd+lp t
     EEA19501.1 1485 VSDSQTFEVTICNMVPK-SLAAALQKFNKFARDSLPSYMVPTAYLIVDRLPTT 1536
                     67888999999999996.4233457788888********************98 PP

>> Symplekin_C  Symplekin tight junction protein C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0    0.0001      0.36      50     140 ..    1447    1547 ..    1422    1579 .. 0.85
   2 ?   -3.7   0.0       2.9     1e+04      93     113 ..    1726    1747 ..    1716    1752 .. 0.58

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.0001
  Symplekin_C   50 ekekspltpaellvalhnlekkkkevelkslvealdlclseke.......vftqevlaaalqqlvee..eplpllfmrtviqalkkypslrefv.s 135 
                   ++++s+ t +el+v + + ++ ++++el  + + +++ +s+ +        + ++ laaalq++ +   ++lp  ++ t +++++  p+ ++ v +
   EEA19501.1 1447 TESNSESTGQELVVFIEQEDSGEDSIELMWMQHRVNCEVSDSQtfevticNMVPKSLAAALQKFNKFarDSLPSYMVPTAYLIVDRLPTTTGRVsH 1542
                   4556677889**********999*****************9997777766666889*******99988899***********************99 PP

  Symplekin_C  136 niLpr 140 
                   ++L +
   EEA19501.1 1543 ELLNK 1547
                   99987 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 2.9
  Symplekin_C   93 vftqevlaaalqqlvee.eplp 113 
                    ++q  l +a++ lv++ + l 
   EEA19501.1 1726 DIDQAKLLNACNTLVKShDILR 1747
                   4555666666666666633333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2103 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       603  (0.0336327); expected 358.6 (0.02)
Passed bias filter:                      560  (0.0312343); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 1.15u 0.38s 00:00:01.52 Elapsed: 00:00:00.52
# Mc/sec: 12062.23
//
Query:       EEA19502.1  [L=356]
Description: siderophore biosynthesis lipase/esterase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-96  323.3   0.0    1.5e-96  323.0   0.0    1.0  1  DUF1749        Protein of unknown function (DUF1749)
     0.0087   16.7   0.0      0.013   16.1   0.0    1.4  1  Abhydrolase_6  Alpha/beta hydrolase family
  ------ inclusion threshold ------
       0.01   15.1   0.0      0.024   13.9   0.0    1.6  1  Hydrolase_4    Serine aminopeptidase, S33
      0.016   14.8   0.0      0.031   13.9   0.0    1.6  1  Abhydrolase_1  alpha/beta hydrolase fold
      0.025   14.4   0.0      0.039   13.8   0.0    1.2  1  DUF5089        Domain of unknown function (DUF5089)
       0.08   11.8   0.0       0.12   11.2   0.0    1.2  1  COesterase     Carboxylesterase family
        0.1   12.1   0.0       0.33   10.4   0.0    1.7  2  DUF900         Alpha/beta hydrolase of unknown function (DUF9
       0.14   11.6   0.0       0.45   10.0   0.0    1.8  2  LIDHydrolase   Lipid-droplet associated hydrolase
       0.19   11.4   0.1        1.4    8.6   0.2    2.4  2  PGAP1          PGAP1-like protein


Domain annotation for each model (and alignments):
>> DUF1749  Protein of unknown function (DUF1749)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  323.0   0.0  7.7e-100   1.5e-96       7     299 .]      12     351 ..       4     351 .. 0.92

  Alignments for each domain:
  == domain 1  score: 323.0 bits;  conditional E-value: 7.7e-100
     DUF1749   7 pgllheyaerlvafeyetsgelkskallFigGLgdGlltvpyvkelanaldeagwsvvelqlsssyggwGtgsLkrDaeeieklveYlkktksG..eek 103
                 pg+lh+y+e lv+fey++s   +++++lF+gGLgdGl t +y+ +l+ al++++ws++ l+l+ssy +wG g L+rD++ei+k+++Y+ ++k+    ++
  EEA19502.1  12 PGILHHYTETLVTFEYTSSAVQQPHSILFVGGLGDGLATTSYTSDLVRALQPTQWSLFTLTLTSSYQSWGLGHLDRDTDEIAKCLQYISEYKTHkfGHD 110
                 79*****************988********************************************************************995423467 PP

     DUF1749 104 kekvvlmGHstGsqdvlyYltssnerd.............rekvdgailqapvsDReailkvlee..........rkklkelvalakkl.....vdkgk 174
                 + k++lmGHstGsq v++Yl+++n+++             r  +dgai+qapvsDReail vl e          r+ + +l ++ak+      + +  
  EEA19502.1 111 NGKIILMGHSTGSQCVMHYLYRPNPHTtapvfdsdlehvkRRVLDGAIMQAPVSDREAILWVLTEgfggktpremREIYGKLEKIAKEAdqqnkETQSP 209
                 89***********************889***********9999*******************************9777777777777653323233455 PP

     DUF1749 175 aeeilprelaekvgl.etpvsarRflsLasvd.....gdDDfFssDlsdeklektfGkvke......pllillsekDefvpesvdkedllerwkeavk. 260
                  +++lp +l++ ++  +tp+sarRflsLas++      +DD+FssD+ +e+l+ktfG++k+      +l++l+s+ D++vpe+vdke+ll +wk+a++ 
  EEA19502.1 210 FDTMLPISLTSLIYPaNTPLSARRFLSLASPEspqspREDDLFSSDIGEEQLAKTFGMIKQqgllkdKLMVLYSGADQSVPEWVDKEKLLLKWKNAADh 308
                 689*******999988****************999989***********************9****99*****************************98 PP

     DUF1749 261 ...kkewsee.sGiipgAsHnveeesaeeaqkelvervlsflk 299
                     ++w++e sGiipgAsH++++++++e ++ lv+rvl +l+
  EEA19502.1 309 ngkFQVWDQEhSGIIPGASHALSNDDQAEPRRDLVRRVLGYLQ 351
                 88667899999*****************************995 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0   6.7e-06     0.013      47     211 ..      92     333 ..      38     345 .. 0.43

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 6.7e-06
                    HHHCHHHHHHHCCTT.......TTSEEEEEETCHHHHHHHHHHCC........................EE.EEES-................--- CS
  Abhydrolase_6  47 ledladlaalldelaa.....gggpvvlvGHSlGGalalaaapla......................lvvg.vlldp..............pptal 100
                        a +++++ e ++     + g+++l+GHS G   +++   ++                      ++ g ++ +p                   
     EEA19502.1  92 I---AKCLQYISEYKThkfghDNGKIILMGHSTGSQCVMH---YLyrpnphttapvfdsdlehvkrrVLDGaIMQAPvsdreailwvltegF---- 177
                    2...333333333333666689999***************...7766666667777777776666654444466666222222222222220.... PP

                    -TTTS----TTHHHHHHTT-CCCCHCCHS-HSCCCCHHH..CCCCHCHCCCGHH.....................HHCCHHCHTTCCHHTT-TTGC CS
  Abhydrolase_6 101 pagllaaalelllallallrllawlsreplprlfladed..adaawrarlarla.....................allaglgllpaaawadlpvpl 173
                                 + ++++++           +++++++  a++a +++  + +                               a+++  l +p 
     EEA19502.1 178 ------------GGKTPREMR-----------EIYGKLEkiAKEADQQNKETQSpfdtmlpisltsliypantplS---------ARRFLSLASPE 241
                    ............222221111...........11111111111111111111111111111111111111111110.........11111111111 PP

                    .....................................EEE.CTT-CHHHHC.............HHCCCHSTTEEET.............CE...S CS
  Abhydrolase_6 174 .....................................lvl.ggeDplvprl.............lerllaqagarlp.............vvlpga 205
                                                         +vl  g+D++vp++             +           +              ++pga
     EEA19502.1 242 spqspreddlfssdigeeqlaktfgmikqqgllkdklMVLySGADQSVPEWvdkeklllkwknaA-----------DhngkfqvwdqehsGIIPGA 326
                    22222222223333333444444455566666666654554599999998833333333333321...........11122333333344778888 PP

                    SS.-HHH CS
  Abhydrolase_6 206 GH.lphl 211
                    +H l ++
     EEA19502.1 327 SHaLSND 333
                    8854444 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   1.2e-05     0.024      68     104 ..     104     140 ..      79     179 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.2e-05
  Hydrolase_4  68 kvkeehpelplfllGhSmGGliallyllrypdkvagl 104
                  ++k  h + +++l+GhS+G+  +++yl r  ++ ++ 
   EEA19502.1 104 THKFGHDNGKIILMGHSTGSQCVMHYLYRPNPHTTAP 140
                  445567777******************8888766554 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   1.6e-05     0.031      70     227 ..     109     291 ..      37     308 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.6e-05
                    CTTSSEEEEEETHHHHHHHHHHHHH............GGGEEEEEEESE......CSSCCHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHHHHCC CS
  Abhydrolase_1  70 lgddkltlvGhSmGGmialayaaey............perVkalvllga......idpaaslieaqrqqaksfpdffdgyaadcarnpagpllade 147
                    ++++k++l+GhS G++++++y+ +              e+Vk+ vl+ga      +d  a l  + +    + p+ ++ ++ + ++ +     +++
     EEA19502.1 109 HDNGKIILMGHSTGSQCVMHYLYRPnphttapvfdsdLEHVKRRVLDGAimqapvSDREAILWVLTEGFGGKTPREMREIYGKLEKIAKEADQQNK 204
                    46789*******************999999999988889999999999988888844444444444444555677777777777777777777777 PP

                    SCHHHHHHHHHHHHHH.......HCHHHCCHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHCTHHHHS.EEEEEEETTCSSSCH CS
  Abhydrolase_1 148 laaleqrhrlvdalkf.......pdkskrfpssgsdnasslatgalksieqwpttdsaklllrlrelknvla.ptlvisgtsDplvpp 227
                     + +++ + l  +l +       p++++rf s  s+ +  + ++++++ + + +++ ak ++++ + +  l+ + +v+++  D+ vp+
     EEA19502.1 205 ETQSPFDTMLPISLTSliypantPLSARRFLSLASPESPQSPREDDLFSSDIGEEQLAKTFGMIKQ-QGLLKdKLMVLYSGADQSVPE 291
                    777777777778887788888888888888888888888888888888888888888888888887.333335777777777777776 PP

>> DUF5089  Domain of unknown function (DUF5089)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0     2e-05     0.039     137     166 ..     180     209 ..     172     220 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2e-05
     DUF5089 137 ktdkeLekilnglkslkkeaevQnkeikkq 166
                 kt +e+ +i+  l ++ kea++Qnke ++ 
  EEA19502.1 180 KTPREMREIYGKLEKIAKEADQQNKETQSP 209
                 799***********************9875 PP

>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   5.9e-05      0.12     170     207 ..      96     134 ..      90     165 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 5.9e-05
                 HHHHHH.HGGGGTEEEEEEEEEEETHHHHHHHHHHHSGG CS
  COesterase 170 LrWVke.nIasFGGdpervtlfGesAGaasvsllllspl 207
                 L++++e + ++FG d  ++ l+G+s G+ +v   l  p 
  EEA19502.1  96 LQYISEyKTHKFGHDNGKIILMGHSTGSQCVMHYLYRPN 134
                 77776635789********************99888765 PP

>> DUF900  Alpha/beta hydrolase of unknown function (DUF900)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   0.00017      0.33      78     140 ..      90     166 ..      85     184 .. 0.74
   2 ?   -1.7   0.0      0.82   1.6e+03     133     166 ..     251     287 ..     248     289 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00017
      DUF900  78 dalekllrylatk......ksakkihllaHSmGtwlvlealrqlaieade.......pavea.kikeviLaAPDidv 140
                 d+++k l+y+ +       +++ ki l+ HS G++ v++ l     ++         ++v+   ++  i+ AP  d+
  EEA19502.1  90 DEIAKCLQYISEYkthkfgHDNGKIILMGHSTGSQCVMHYLYRPNPHTTApvfdsdlEHVKRrVLDGAIMQAPVSDR 166
                 67888888888876667777789****************99876666655556644433333466666666666665 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.82
      DUF900 133 LaAPDidvdvfkkqle...slgkeskeltvyvsrdDr 166
                 L++ Di  +   k +    + g  + +l v++s  D+
  EEA19502.1 251 LFSSDIGEEQLAKTFGmikQQGLLKDKLMVLYSGADQ 287
                 4566666666666555555777777999999999997 PP

>> LIDHydrolase  Lipid-droplet associated hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00023      0.45      68     105 ..      95     132 ..      89     164 .. 0.81
   2 ?   -2.7   0.0       1.7   3.4e+03     225     240 ..     273     292 ..     228     300 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00023
  LIDHydrolase  68 kedflkellekaksekdvklilvGHSvGaYialevlkr 105
                     +++ e+ +++  +++ k+il+GHS G+  +++ l r
    EEA19502.1  95 CLQYISEYKTHKFGHDNGKIILMGHSTGSQCVMHYLYR 132
                   55666666666778899************999887765 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 1.7
  LIDHydrolase 225 a....lvfyfgkkDhWvpee 240
                        l+++++  D+ vpe 
    EEA19502.1 273 LlkdkLMVLYSGADQSVPEW 292
                   14444888899888877765 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.2    0.0007       1.4      47     101 ..      67     122 ..      34     223 .. 0.86
   2 ?   -0.3   0.0      0.37   7.3e+02      34      74 ..     237     276 ..     175     290 .. 0.59

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0007
       PGAP1  47 dfftvdfneelsaldGrtlldqaeylndaIkyIlslyssse..keptsviliGHSmG 101
                 + ft  +   +     + l + ++ + ++++yI + y++++  +++ ++il+GHS G
  EEA19502.1  67 SLFTLTLTSSYQSWGLGHLDRDTDEIAKCLQYISE-YKTHKfgHDNGKIILMGHSTG 122
                 55777777777777678899999999******755.656551256789*******99 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.37
       PGAP1  34 lrkllknqnkkeldfftvdfneelsaldGrtlldqaeylnd 74 
                 l + ++ q ++e d f+ d +ee  a   ++++ q+ +l+d
  EEA19502.1 237 LASPESPQSPREDDLFSSDIGEEQLAKTFGMIK-QQGLLKD 276
                 333366677777888888888888887555544.6666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (356 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       469  (0.0261587); expected 358.6 (0.02)
Passed bias filter:                      447  (0.0249317); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 2356.40
//
Query:       EEA19503.1  [L=356]
Description: siderophore biosynthesis lipase/esterase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.7e-93  310.7   0.0    1.1e-92  310.4   0.0    1.0  1  DUF1749        Protein of unknown function (DUF1749)
     0.0088   16.7   0.0      0.013   16.1   0.0    1.4  1  Abhydrolase_6  Alpha/beta hydrolase family
  ------ inclusion threshold ------
      0.011   15.1   0.0      0.024   13.9   0.0    1.6  1  Hydrolase_4    Serine aminopeptidase, S33
      0.015   14.9   0.0      0.029   14.0   0.0    1.6  1  Abhydrolase_1  alpha/beta hydrolase fold
      0.025   14.5   0.0      0.039   13.8   0.0    1.2  1  DUF5089        Domain of unknown function (DUF5089)
      0.063   12.1   0.0       0.12   11.2   0.0    1.4  1  COesterase     Carboxylesterase family
        0.1   12.1   0.0       0.33   10.4   0.0    1.7  2  DUF900         Alpha/beta hydrolase of unknown function (DUF9
       0.17   11.4   0.0       0.45   10.0   0.0    1.7  2  LIDHydrolase   Lipid-droplet associated hydrolase
       0.19   11.4   0.1        1.7    8.3   0.2    2.4  2  PGAP1          PGAP1-like protein


Domain annotation for each model (and alignments):
>> DUF1749  Protein of unknown function (DUF1749)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  310.4   0.0   5.4e-96   1.1e-92      14     299 .]      19     351 ..      11     351 .. 0.92

  Alignments for each domain:
  == domain 1  score: 310.4 bits;  conditional E-value: 5.4e-96
     DUF1749  14 aerlvafeyetsgelkskallFigGLgdGlltvpyvkelanaldeagwsvvelqlsssyggwGtgsLkrDaeeieklveYlkktksG..eekkekvvlm 110
                 +e lv+fey++s   +++++lF+gGLgdGl t +y+ +l+ al++++ws++ l+l+ssy +wG g L+rD++ei+k+++Y+ ++k+    +++ k++lm
  EEA19503.1  19 TETLVTFEYTSSAVQQPHSILFVGGLGDGLATTSYTSDLVRALQPTQWSLFTLTLTSSYQSWGLGHLDRDTDEIAKCLQYISEYKTHkfGHDNGKIILM 117
                 57789******9988********************************************************************99542346789***** PP

     DUF1749 111 GHstGsqdvlyYltssnerd.............rekvdgailqapvsDReailkvlee..........rkklkelvalakkl.....vdkgkaeeilpr 181
                 GHstGsq v++Yl+++n+++             r  +dgai+qapvsDReail vl e          r+ + +l ++ak+      + +   +++lp 
  EEA19503.1 118 GHSTGSQCVMHYLYRPNPHTtapvfdsdlehvkRRVLDGAIMQAPVSDREAILWVLTEgfggktpremREIYGKLEKIAKEAdqqnkETQSPFDTMLPI 216
                 ******************889***********9999*******************************9777777777777653323233455689**** PP

     DUF1749 182 elaekvgl.etpvsarRflsLasvd.....gdDDfFssDlsdeklektfGkvke......pllillsekDefvpesvdkedllerwkeavk....kkew 264
                 +l++ ++  +tp+sarRflsLas++      +DD+FssD+ +e+l+ktfG++k+      +l++l+s+ D++vpe+vdke+ll +wk+a++     ++w
  EEA19503.1 217 SLTSLIYPaNTPLSARRFLSLASPEspqspREDDLFSSDIGEEQLAKTFGMIKQqgllkdKLMVLYSGADQSVPEWVDKEKLLLKWKNAADhngkFQVW 315
                 ***999988****************999989***********************9****99*****************************988866789 PP

     DUF1749 265 see.sGiipgAsHnveeesaeeaqkelvervlsflk 299
                 ++e sGiipgAsH++++++++e ++ lv+rvl +l+
  EEA19503.1 316 DQEhSGIIPGASHALSNDDQAEPRRDLVRRVLGYLQ 351
                 9999*****************************995 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0   6.7e-06     0.013      47     211 ..      92     333 ..      38     345 .. 0.43

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 6.7e-06
                    HHHCHHHHHHHCCTT.......TTSEEEEEETCHHHHHHHHHHCC........................EE.EEES-................--- CS
  Abhydrolase_6  47 ledladlaalldelaa.....gggpvvlvGHSlGGalalaaapla......................lvvg.vlldp..............pptal 100
                        a +++++ e ++     + g+++l+GHS G   +++   ++                      ++ g ++ +p                   
     EEA19503.1  92 I---AKCLQYISEYKThkfghDNGKIILMGHSTGSQCVMH---YLyrpnphttapvfdsdlehvkrrVLDGaIMQAPvsdreailwvltegF---- 177
                    2...333333333333666689999***************...7766666667777777776666654444466666222222222222220.... PP

                    -TTTS----TTHHHHHHTT-CCCCHCCHS-HSCCCCHHH..CCCCHCHCCCGHH.....................HHCCHHCHTTCCHHTT-TTGC CS
  Abhydrolase_6 101 pagllaaalelllallallrllawlsreplprlfladed..adaawrarlarla.....................allaglgllpaaawadlpvpl 173
                                 + ++++++           +++++++  a++a +++  + +                               a+++  l +p 
     EEA19503.1 178 ------------GGKTPREMR-----------EIYGKLEkiAKEADQQNKETQSpfdtmlpisltsliypantplS---------ARRFLSLASPE 241
                    ............222221111...........11111111111111111111111111111111111111111110.........11111111111 PP

                    .....................................EEE.CTT-CHHHHC.............HHCCCHSTTEEET.............CE...S CS
  Abhydrolase_6 174 .....................................lvl.ggeDplvprl.............lerllaqagarlp.............vvlpga 205
                                                         +vl  g+D++vp++             +           +              ++pga
     EEA19503.1 242 spqspreddlfssdigeeqlaktfgmikqqgllkdklMVLySGADQSVPEWvdkeklllkwknaA-----------DhngkfqvwdqehsGIIPGA 326
                    22222222223333333444444455566666666654554599999998833333333333321...........11122333333344778888 PP

                    SS.-HHH CS
  Abhydrolase_6 206 GH.lphl 211
                    +H l ++
     EEA19503.1 327 SHaLSND 333
                    8854444 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   1.2e-05     0.024      68     104 ..     104     140 ..      79     179 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.2e-05
  Hydrolase_4  68 kvkeehpelplfllGhSmGGliallyllrypdkvagl 104
                  ++k  h + +++l+GhS+G+  +++yl r  ++ ++ 
   EEA19503.1 104 THKFGHDNGKIILMGHSTGSQCVMHYLYRPNPHTTAP 140
                  445567777******************8888766554 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   1.5e-05     0.029      70     227 ..     109     291 ..      37     315 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1.5e-05
                    CTTSSEEEEEETHHHHHHHHHHHHH............GGGEEEEEEESE......CSSCCHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHHHHCC CS
  Abhydrolase_1  70 lgddkltlvGhSmGGmialayaaey............perVkalvllga......idpaaslieaqrqqaksfpdffdgyaadcarnpagpllade 147
                    ++++k++l+GhS G++++++y+ +              e+Vk+ vl+ga      +d  a l  + +    + p+ ++ ++ + ++ +     +++
     EEA19503.1 109 HDNGKIILMGHSTGSQCVMHYLYRPnphttapvfdsdLEHVKRRVLDGAimqapvSDREAILWVLTEGFGGKTPREMREIYGKLEKIAKEADQQNK 204
                    46789*******************999999999988889999999999988888844444444444444555677777788888887777777777 PP

                    SCHHHHHHHHHHHHHH.......HCHHHCCHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHCTHHHHS.EEEEEEETTCSSSCH CS
  Abhydrolase_1 148 laaleqrhrlvdalkf.......pdkskrfpssgsdnasslatgalksieqwpttdsaklllrlrelknvla.ptlvisgtsDplvpp 227
                     + +++ + l  +l +       p++++rf s  s+ +  + ++++++ + + +++ ak ++++ + +  l+ + +v+++  D+ vp+
     EEA19503.1 205 ETQSPFDTMLPISLTSliypantPLSARRFLSLASPESPQSPREDDLFSSDIGEEQLAKTFGMIKQ-QGLLKdKLMVLYSGADQSVPE 291
                    777777777778887788888888888888888888888888888888888888888888888888.333445777788888887776 PP

>> DUF5089  Domain of unknown function (DUF5089)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0     2e-05     0.039     137     166 ..     180     209 ..     172     220 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2e-05
     DUF5089 137 ktdkeLekilnglkslkkeaevQnkeikkq 166
                 kt +e+ +i+  l ++ kea++Qnke ++ 
  EEA19503.1 180 KTPREMREIYGKLEKIAKEADQQNKETQSP 209
                 799***********************9875 PP

>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   5.9e-05      0.12     170     207 ..      96     134 ..      90     165 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 5.9e-05
                 HHHHHH.HGGGGTEEEEEEEEEEETHHHHHHHHHHHSGG CS
  COesterase 170 LrWVke.nIasFGGdpervtlfGesAGaasvsllllspl 207
                 L++++e + ++FG d  ++ l+G+s G+ +v   l  p 
  EEA19503.1  96 LQYISEyKTHKFGHDNGKIILMGHSTGSQCVMHYLYRPN 134
                 77776635789********************99888765 PP

>> DUF900  Alpha/beta hydrolase of unknown function (DUF900)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   0.00017      0.33      78     140 ..      90     166 ..      85     184 .. 0.74
   2 ?   -1.7   0.0      0.82   1.6e+03     133     166 ..     251     287 ..     248     289 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00017
      DUF900  78 dalekllrylatk......ksakkihllaHSmGtwlvlealrqlaieade.......pavea.kikeviLaAPDidv 140
                 d+++k l+y+ +       +++ ki l+ HS G++ v++ l     ++         ++v+   ++  i+ AP  d+
  EEA19503.1  90 DEIAKCLQYISEYkthkfgHDNGKIILMGHSTGSQCVMHYLYRPNPHTTApvfdsdlEHVKRrVLDGAIMQAPVSDR 166
                 67888888888876667777789****************99876666655556644433333466666666666665 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.82
      DUF900 133 LaAPDidvdvfkkqle...slgkeskeltvyvsrdDr 166
                 L++ Di  +   k +    + g  + +l v++s  D+
  EEA19503.1 251 LFSSDIGEEQLAKTFGmikQQGLLKDKLMVLYSGADQ 287
                 4566666666666555555777777999999999997 PP

>> LIDHydrolase  Lipid-droplet associated hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00023      0.45      68     105 ..      95     132 ..      89     164 .. 0.81
   2 ?   -2.7   0.0       1.7   3.4e+03     225     240 ..     273     292 ..     228     300 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00023
  LIDHydrolase  68 kedflkellekaksekdvklilvGHSvGaYialevlkr 105
                     +++ e+ +++  +++ k+il+GHS G+  +++ l r
    EEA19503.1  95 CLQYISEYKTHKFGHDNGKIILMGHSTGSQCVMHYLYR 132
                   55666666666778899************999887765 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 1.7
  LIDHydrolase 225 a....lvfyfgkkDhWvpee 240
                        l+++++  D+ vpe 
    EEA19503.1 273 LlkdkLMVLYSGADQSVPEW 292
                   14444888899888877765 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   0.2   0.00085       1.7      48     101 ..      68     122 ..      49     223 .. 0.86
   2 ?   -0.5   0.0      0.41   8.1e+02      34      74 ..     237     276 ..     185     290 .. 0.57

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00085
       PGAP1  48 fftvdfneelsaldGrtlldqaeylndaIkyIlslyssse..keptsviliGHSmG 101
                  ft  +   +     + l + ++ + ++++yI + y++++  +++ ++il+GHS G
  EEA19503.1  68 LFTLTLTSSYQSWGLGHLDRDTDEIAKCLQYISE-YKTHKfgHDNGKIILMGHSTG 122
                 5666666666666667899999999******755.656551256789*******99 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.41
       PGAP1  34 lrkllknqnkkeldfftvdfneelsaldGrtlldqaeylnd 74 
                 l + ++ q ++e d f+ d +ee  a   ++++ q+ +l+d
  EEA19503.1 237 LASPESPQSPREDDLFSSDIGEEQLAKTFGMIK-QQGLLKD 276
                 333466677777888999999988888555544.6666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (356 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       473  (0.0263818); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 2366.03
//
Query:       EEA19504.1  [L=359]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.1e-20   73.0   0.0    3.9e-18   65.6   0.0    2.1  2  adh_short       short chain dehydrogenase
    9.2e-14   51.6   0.0    2.2e-12   47.1   0.0    2.1  2  adh_short_C2    Enoyl-(Acyl carrier protein) reductase
      5e-06   26.6   0.0    8.2e-06   25.8   0.0    1.3  1  KR              KR domain
     0.0042   17.1   0.0     0.0074   16.3   0.0    1.4  1  Shikimate_DH    Shikimate / quinate 5-dehydrogenase
  ------ inclusion threshold ------
      0.047   14.4   0.2        5.1    7.9   0.0    2.3  2  DUF3073         Protein of unknown function (DUF3073)
       0.05   14.0   0.1       0.14   12.5   0.1    1.8  1  GHMP_kinases_C  GHMP kinases C terminal


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.6   0.0   1.3e-21   3.9e-18       1     138 [.      28     176 ..      28     184 .. 0.89
   2 !    5.4   0.0    0.0038        11     145     189 ..     223     268 ..     217     273 .. 0.80

  Alignments for each domain:
  == domain 1  score: 65.6 bits;  conditional E-value: 1.3e-21
                 SEEEEESTTS.HHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHT..TSEEEEEE-TTTSHHHHHHHHHHHH..HHHSSESEEEE---SS--SSG CS
   adh_short   1 kvvlvtGass.GIGraiakelakeGakvvv.vdrseekleevakelkee..gakalaiqvDvtdreevealvekav..kklgkldvLvnNAGitgsgpf 93 
                 k+v++tG  + GIG+  a+ +a++G  +++ ++r+ +kl+e ++++k++  + ++ a+++D++++++v+++ +     +++ ++d+Lvn AGi    p 
  EEA19504.1  28 KTVVITGVNRgGIGYSAAESFASQGPAHLIvTGRTMSKLQESIDSMKAKypNVDYRALHIDLSSQQSVRTAAAGLLswADVPTIDILVNSAGI-ALLPE 125
                 79*****97637*************666655******************99999*******************99722466************.79999 PP

                 GGCSHHHHHHHHHHHTHHHHHHHHHHHHHHH......HCTTEEEEEEEEGG CS
   adh_short  94 selseeewervievNltgvflltravlpaml......kqssGrIvnvsSva 138
                   l+ + +e ++++N +g fl + +++p+++       + s rI+nvsS  
  EEA19504.1 126 RTLNVDGIEIIFATNHVGHFLFANLLMPKLIkaaektPKGSTRIINVSSGS 176
                 9*****************************9998855456669******75 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.0038
                 TBHHHHHHHHHHHHH.HHHHHHHHGGGTEEEEEEEESSBSSHHHHH CS
   adh_short 145 gvaaYsAsKaavagl.trslakelaptgirvnavaPGlvdTdmake 189
                  + aY  sK a + + + +  + ++++gi   a++PG+++T++ ++
  EEA19504.1 223 PLEAYNVSKIANVLFgIGATNRLYEKYGILSLALHPGVIKTELGRS 268
                 5679999**9999993455666778899**************9876 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.1   0.0   7.3e-16   2.2e-12       1     130 [.      34     176 ..      34     192 .. 0.85
   2 ?    2.4   0.0     0.033        98     139     182 ..     225     269 ..     217     289 .. 0.68

  Alignments for each domain:
  == domain 1  score: 47.1 bits;  conditional E-value: 7.3e-16
                   TTT.TSHHHHHHHHHHHTT.-EEEEEESSGGH.HHHHHHHHHHTTSE.E..EE--TTSHHHHHHHHHHHHHHH..SSEEEEEE-----EGCSS-GGG CS
  adh_short_C2   1 Gaa.sgIGraiAkalaeeG.aevvltdlneea.kkrveelaeelgae.v..lecDVtdeeqvealveevvekf..gklDilvnnagiapklkgpfle 89 
                   G+   gIG+ +A+++a++G a++++t +  ++ +++++++++++++  +  l++D +++++v+++++ + +     ++Dilvn+agia     p  +
    EEA19504.1  34 GVNrGGIGYSAAESFASQGpAHLIVTGRTMSKlQESIDSMKAKYPNVdYraLHIDLSSQQSVRTAAAGLLSWAdvPTIDILVNSAGIALL---PERT 127
                   566679*************899*********99**********99554445******************9876669*************9...5567 PP

                   H-HHHHHHHHHHHTHHHHHHHHHHHH.HCTSC.......CEEEEEEEGG CS
  adh_short_C2  90 tsreefdraldvnlyslfllakaalp.lmkeg.......gsivnlssvg 130
                   ++ ++++ ++++n  + fl+a+ ++p l+k+         +i+n+ss +
    EEA19504.1 128 LNVDGIEIIFATNHVGHFLFANLLMPkLIKAAektpkgsTRIINVSSGS 176
                   7889**********************85554445688556699999865 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.033
                   THHHHHHHHHHHHHHHHHHH.HGGGTEEEEEEEE--BHCTGGGGS CS
  adh_short_C2 139 naygaaKaalealtrylAve.lgpkgiRvNavspgpikTlaasgi 182
                   +ay+++K a + +   + +  + ++gi   a +pg+ikT++ +++
    EEA19504.1 225 EAYNVSKIANVLFGIGATNRlYEKYGILSLALHPGVIKTELGRSA 269
                   57777777655555544444156699999***********96544 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   0.0   2.8e-09   8.2e-06       2      91 ..      29     120 ..      28     125 .. 0.81

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 2.8e-09
                 EEEEETTT.SHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHT..T-EEEE----TT-HHHHHHHHHHHHHHS..S---EEEE---- CS
          KR   2 tylitGGl.GgLGlelarwlaekgarhlvllsRsaaadedskaliaeleal..gaevevvaaDvsdkdavealleeikaee..ppikGvihaAgv 91 
                 t++itG   Gg+G + a+  a++g +hl++++R+    ++ ++ i++++a+  +++ +++++D+s++++v+++ + + + +  p+i   +++Ag+
  EEA19504.1  29 TVVITGVNrGGIGYSAAESFASQGPAHLIVTGRT---MSKLQESIDSMKAKypNVDYRALHIDLSSQQSVRTAAAGLLSWAdvPTIDILVNSAGI 120
                 6789996449************************...3455668999999844566666789**********99988765556888888888886 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   2.5e-06    0.0074       1      65 [.      16      81 ..      16     101 .. 0.83

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 2.5e-06
                  HHHHHHHS..TT-EEEEES-..SHHHHHHHHHHHCCT-CEEEEEESSHHHHHHHHHHHT.ET-EEEE CS
  Shikimate_DH  1 elakkkleslkekkvlliGa..GemaelvakhLlakgvkkvvvaNRtlerakelaeelkgeeiealk 65
                  e+a+  ++++++k+v++ G   G ++  +a+ ++++g  +++v++Rt+++ +e  +++k++ +  ++
    EEA19504.1 16 EVAQAFVDNIRGKTVVITGVnrGGIGYSAAESFASQGPAHLIVTGRTMSKLQESIDSMKAK-YPNVD 81
                  57899999*********99555******************************999999766.44444 PP

>> DUF3073  Protein of unknown function (DUF3073)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   0.0    0.0017       5.1      15      39 ..      72      96 ..      60     102 .. 0.81
   2 ?    4.2   0.0     0.025        75      21      46 ..     186     211 ..     183     229 .. 0.74

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0017
     DUF3073 15 eLKYlspetDydaLerELsgksees 39
                 +K   p++Dy+aL+ +Ls++++ +
  EEA19504.1 72 SMKAKYPNVDYRALHIDLSSQQSVR 96
                578899************9988755 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.025
     DUF3073  21 petDydaLerELsgkseesdsaddee 46 
                  ++++++L+++L ++++++ + ++  
  EEA19504.1 186 SDMNFEKLNKDLPEQEQPNYDLQRGW 211
                 589*********99988776655554 PP

>> GHMP_kinases_C  GHMP kinases C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.1   4.7e-05      0.14      30      64 ..     267     299 ..     250     318 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 4.7e-05
  GHMP_kinases_C  30 gilppeleellealselGalgaklsGaGgGptvfa 64 
                     ++  pe++++++al+e G ++++  Ga  G++  +
      EEA19504.1 267 RSALPEITAAVDALREKGYYAYRSLGA--GASTTM 299
                     56679**********************..988655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (359 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       393  (0.0219198); expected 358.6 (0.02)
Passed bias filter:                      383  (0.021362); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.50u 0.30s 00:00:00.80 Elapsed: 00:00:00.45
# Mc/sec: 2378.91
//
Query:       EEA19505.1  [L=369]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.1e-11   41.2   0.8    2.3e-07   30.0   0.1    2.1  2  Fungal_trans_2  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.0   0.1   1.3e-11   2.3e-07      21     143 ..      23     135 ..       7     147 .. 0.85
   2 !    9.8   0.1   1.7e-05       0.3     259     339 ..     235     325 ..     167     339 .. 0.66

  Alignments for each domain:
  == domain 1  score: 30.0 bits;  conditional E-value: 1.3e-11
  Fungal_trans_2  21 snpfrkvllplalsnkallhallals..afhlqskgpkdslereakrykslalkelqealaelsstlsrnekykdiLaaiLllcsieissgdvsd 113
                      +  + + l + ls+ka +h ++a++  + h  s g+++   ++a++++s++l ++ + la +++ ++      ++L  i ++++ e +   v +
      EEA19505.1  23 PDDAKYWWLRFVLSDKAAYHVIIAVAeaCNHYLSGGGES--TSQALYHRSRTLALVAQRLAGKDALSD------STLGVIVMMIVQEQMRKVVFE 109
                     566789999****************64488889999999..9**********************9999......*************88888888 PP

  Fungal_trans_2 114 wrvhLeaatsliksrggskasssslsskar 143
                      ++h e+ +++i+ rgg+    ++l++ + 
      EEA19505.1 110 AHIHYEGLRRMIEARGGL----DQLEQSPT 135
                     9*****************....44444444 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 1.7e-05
  Fungal_trans_2 259 s..........kdltelfrlaaliylyrlvlglppsspevqelv.kkllellellpsspvaiasLlWplFiaGceavdeddRdfvrrrleel 339
                     +          ++l +++++ + +++ +l+++++ +  +  ++v ++l ++l +  +    ++  lW lFi G+  +d++d ++++ +++++
      EEA19505.1 235 RfqplhetsslSNLEKVYHIGLTLFMITLFMQFDQHRLLKCDAVfSRLRSILYRDLDEID-NNLALWILFIGGIWITDGPDDSWLHWMIKKM 325
                     0333334433345569********************554444441444444444444444.56667************97766665555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (369 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       403  (0.0224776); expected 358.6 (0.02)
Passed bias filter:                      345  (0.0192426); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2591.20
//
Query:       EEA19506.1  [L=345]
Description: aldo/keto reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-73  247.9   0.0    1.4e-73  247.7   0.0    1.0  1  Aldo_ket_red  Aldo/keto reductase family
  ------ inclusion threshold ------
       0.11   11.9   0.0         12    5.1   0.0    2.1  2  DnaB_C        DnaB-like helicase C terminal domain


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  247.7   0.0   1.6e-77   1.4e-73       2     293 ..      21     320 ..      20     321 .. 0.96

  Alignments for each domain:
  == domain 1  score: 247.7 bits;  conditional E-value: 1.6e-77
                   EEEE-SSS-ST....TS-HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH-TTTGGG-EEEEEE..--SSSTTSSSS-HHHHHHHHHHH CS
  Aldo_ket_red   2 lglGtwqlgsk...eeiskeealellrraleaGinffDtAevYgkgqseellGealkksrkkreeviiatKv..dlrdaeiksglskenireslees 93 
                   lglG++ +++    ++ s+ee +++l+ra+e G + +Dt+++Y  g  eellG++++k ++kr+++++atK    ++  +  ++ s++ + +++ es
    EEA19506.1  21 LGLGLMGMSWTfygNTPSDEERFAVLDRAVEIGATSWDTSDMY--GDGEELLGKWFNK-SGKRDKIFLATKFafVKGLPNFVVDSSAAYCKKACAES 114
                   8******************************************..999**********.*************7767777889999************ PP

                   HHHHT-S-EEEEEE-S--TTS-.HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHHHHTTT--EEEEE-B-BTT....-HHHHTTHHHHHHHTT-EE CS
  Aldo_ket_red  94 lkrLgtdyvDllllHrpdpslpsieevldaleelvkeGkiraiGvSnfsveqlekakkkkkvkivavqveynll....releeegllelckkkgvpl 186
                   lk Lgtdy+Dl+++Hr +p++p iee+++a++el+ eGki+++G+S++s   l++a   k+  i avqvey+ +    +e + ++ll  ++++gv++
    EEA19506.1 115 LKLLGTDYIDLYYMHRANPDTP-IEETVRAMAELKAEGKIKYLGLSEVSSTTLRRA--CKVAHIDAVQVEYSAFvtdiEEKNGTNLLAIARELGVAV 208
                   **********************.*******************************99..9****************9888888899************ PP

                   EEBSTTGGGTTGTTTSS---SSSCCC-------.....TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTSTT-SEEEE--SSHHHHHHHHGGGG CS
  Aldo_ket_red 187 iaysplggGlltgkyqseedkedkeprkdlkrd.....ertsknldaaeelselakehgvslaqlalryalsqpavgivipgasnieqlednldale 278
                   iaysplg+G+ltg y +++++  ++ ++   ++     e+++ n +++ +l+++a  ++++laqla++++l+q   +i+ipg+++i  le+n ++l 
    EEA19506.1 209 IAYSPLGRGILTGAYSKKDSVSAEGDQRTEMEFpmfaeENLEANVKLVGKLRDIADRKNCTLAQLAIAWLLKQGDYIIPIPGTKKIRYLEENWASLR 305
                   *******************999777776655669*************************************************************** PP

                   ----HHHHHHHHHHH CS
  Aldo_ket_red 279 lklseeevaeldell 293
                   ++l++ee ae+++l+
    EEA19506.1 306 VELTDEEEAEMRKLI 320
                   **********99986 PP

>> DnaB_C  DnaB-like helicase C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0    0.0018        16     107     185 ..      93     168 ..      78     177 .. 0.82
   2 ?    5.1   0.0    0.0014        12     160     182 ..     196     218 ..     172     230 .. 0.88

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.0018
                 EEXSSXCHHHHHHHHHHHHHHTTEEEEEEEEGGGTBTSCSSSCCCHHHHHHHHHHHHHHHHCTSXEEEEEEXSGGGCCS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      DnaB_C 107 ddtpaltvseirskarrlkkekglgliviDyLqlmegseekenreqevseisrsLkalakelnvpvialsqLsravesr 185
                 +  p++ v +  + +++  + ++l+l+  Dy++l     ++ n  + + e  r++ +l  e ++  + ls +s ++ +r
  EEA19506.1  93 KGLPNFVVDSSAAYCKKACA-ESLKLLGTDYIDLYYM--HRANPDTPIEETVRAMAELKAEGKIKYLGLSEVSSTTLRR 168
                 55566666666777777744.89***********994..3579999************************999887766 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0014
                 HHHHHHHHCTSXEEEEEEXSGGG CS
                 xxxxxxxxxxxxxxxxxxxxxxx RF
      DnaB_C 160 sLkalakelnvpvialsqLsrav 182
                 +L a+a+el v via s L r +
  EEA19506.1 196 NLLAIARELGVAVIAYSPLGRGI 218
                 6889**************99975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (345 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       394  (0.0219756); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.49
# Mc/sec: 2135.96
//
Query:       EEA19507.1  [L=142]
Description: sorting nexin Snx3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-27   96.3   0.2    1.3e-27   96.1   0.2    1.1  1  PX        PX domain


Domain annotation for each model (and alignments):
>> PX  PX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   96.1   0.2     7e-32   1.3e-27       2     111 ..      21     133 ..      20     135 .. 0.96

  Alignments for each domain:
  == domain 1  score: 96.1 bits;  conditional E-value: 7e-32
                 SEEEEEEEEEEEETTSSEEEEEEEEEETTS.....SSEEEEEEEHHHHHHHHHHHHHHHTTSTSTSSSTSGSSSSSCTTSHHHHHHHHHHHHHHHHHHH CS
          PX   2 dlaqvsvleretsgskkhsyylyevelktg.....akewtvkRrYsdFeeLhskLlrkfprvkiPplPkkvlfgsvrkkdeefiekrrkgLeeyLqrll 95 
                 ++++++v +++t+g++++ y+ ye+ ++t+      k++ v+RrYsdFe +++ L+r+  rv+iPplP+kv   +   +++e+ie+rr+gL+++Lq ++
  EEA19507.1  21 NFLEIEVRNPQTHGTSRSMYTSYEIVCRTNipafkLKQSVVRRRYSDFEYFRDILERESSRVTIPPLPGKVFTNR---FSDEVIEHRREGLQRFLQIVA 116
                 68899******************************************************************7766...********************* PP

                 TSCHHHH.SHHHHHHHH CS
          PX  96 nhpelrn.sevlteFLe 111
                  hp l+  s+vl +F++
  EEA19507.1 117 GHPLLQTgSKVLASFIQ 133
                 ***************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (142 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       267  (0.0148921); expected 358.6 (0.02)
Passed bias filter:                      250  (0.0139439); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1034.41
//
Query:       EEA19508.1  [L=690]
Description: MYB DNA-binding domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.4e-16   58.6   0.0    4.3e-08   33.3   0.0    2.4  2  Myb_DNA-bind_6   Myb-like DNA-binding domain
    1.9e-14   53.6   0.1    1.4e-06   28.4   0.1    2.5  2  Myb_DNA-binding  Myb-like DNA-binding domain
     0.0034   17.6   3.3      0.033   14.4   0.0    3.5  4  FXR_C1           Fragile X-related 1 protein C-terminal regio
  ------ inclusion threshold ------
      0.049   13.6   0.0         16    5.6   0.0    2.5  2  SLIDE            SLIDE


Domain annotation for each model (and alignments):
>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.0   1.7e-08   7.6e-05       1      57 [.     297     357 ..     297     360 .. 0.82
   2 !   33.3   0.0   9.6e-12   4.3e-08       1      47 [.     480     529 ..     480     537 .. 0.85

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 1.7e-08
  Myb_DNA-bind_6   1 WteeEdeiLlklvekyg.ndWknIaea..ln..rRtpkqcfdrwknkLrpkisrkkwskeed 57 
                     Wt++E+  Llk+v k+g  +W+ I ++  ln  +R++ +++dr++  ++p  + ++ ++e +
      EEA19508.1 297 WTDQETTDLLKGVVKCGiGNWTAILQQpeLNfnKRSAANLKDRFRV-CCPWAYGAADPNEAT 357
                     *****************77*****555445555************9.988777776666655 PP

  == domain 2  score: 33.3 bits;  conditional E-value: 9.6e-12
  Myb_DNA-bind_6   1 WteeEdeiLlklvekygndWknIaea..ln..rRtpkqcfdrwknkLrpki 47 
                     +t++Ede+Llk++  +g++W++I++   ln  +R++++++dr+++k  p+ 
      EEA19508.1 480 FTPAEDEALLKGYAVHGFQWTLIQQDkhLNlsHRRATDLRDRFRTKF-PNA 529
                     79*********************776436699************965.444 PP

>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.4   0.1   3.1e-10   1.4e-06       3      43 ..     296     341 ..     294     343 .. 0.92
   2 !   22.9   0.0   1.6e-08   7.2e-05       1      44 [.     477     524 ..     477     526 .. 0.93

  Alignments for each domain:
  == domain 1  score: 28.4 bits;  conditional E-value: 3.1e-10
                      SSBHHHHHHHHHHHHHHT.TCHHHHHH....HHTSS-HHHHHHHHH CS
  Myb_DNA-binding   3 kWteeEdelLleavkkhG.nrWkkIae....rlggRtekqcrsrwr 43 
                      +Wt +E   Ll++v k G ++W++I++     ++ R++ + ++r+r
       EEA19508.1 296 RWTDQETTDLLKGVVKCGiGNWTAILQqpelNFNKRSAANLKDRFR 341
                      8************************9999666669**********8 PP

  == domain 2  score: 22.9 bits;  conditional E-value: 1.6e-08
                      CSSSBHHHHHHHHHHHHHHTTCHHHHHH..HHT..SS-HHHHHHHHHH CS
  Myb_DNA-binding   1 rgkWteeEdelLleavkkhGnrWkkIae..rlg..gRtekqcrsrwrn 44 
                      r ++t+ Ede Ll++ + hG +W++I +  +l+   R + + r+r+r+
       EEA19508.1 477 RRPFTPAEDEALLKGYAVHGFQWTLIQQdkHLNlsHRRATDLRDRFRT 524
                      679***********************9989888868**********96 PP

>> FXR_C1  Fragile X-related 1 protein C-terminal region 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   0.3         4   1.8e+04      47      53 ..     135     141 ..     132     141 .. 0.63
   2 !   14.4   0.0   7.4e-06     0.033      25      61 ..     271     308 ..     261     312 .. 0.86
   3 ?   -4.3   0.1         4   1.8e+04      18      32 ..     348     363 ..     347     366 .. 0.73
   4 ?    1.6   0.0     0.071   3.2e+02      42      61 ..     471     491 ..     462     494 .. 0.76

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 4
      FXR_C1  47 sRRRRtD 53 
                 s+RRR D
  EEA19508.1 135 SKRRRID 141
                 6677765 PP

  == domain 2  score: 14.4 bits;  conditional E-value: 7.4e-06
      FXR_C1  25 etdqtaDtdasesqlsanRRRRsRRRRtDedat.lmDG 61 
                   d+++D+da  s ++  R R+  RR tD+++t l+ G
  EEA19508.1 271 PGDKPVDADAPLSPKTRGRSRKNLRRWTDQETTdLLKG 308
                 5699***************************9845555 PP

  == domain 3  score: -4.3 bits;  conditional E-value: 4
      FXR_C1  18 yslldtn.etdqtaDt 32 
                 y+++d n  t q  Dt
  EEA19508.1 348 YGAADPNeATKQIQDT 363
                 8999988557787887 PP

  == domain 4  score: 1.6 bits;  conditional E-value: 0.071
      FXR_C1  42 nRRRRsRRRRt.DedatlmDG 61 
                 + +RRsRR  t  ed +l+ G
  EEA19508.1 471 KSKRRSRRPFTpAEDEALLKG 491
                 568*****9884578888877 PP

>> SLIDE  SLIDE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0    0.0035        16      46      78 ..     291     323 ..     279     361 .. 0.84
   2 ?    5.4   0.0    0.0041        18      43      78 ..     471     505 ..     452     514 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0035
       SLIDE  46 nkgkkeyteeeDrfllvllakyGygnyekikke 78 
                  k+ + +t++e   ll  + k+G+gn+  i ++
  EEA19508.1 291 RKNLRRWTDQETTDLLKGVVKCGIGNWTAILQQ 323
                 455667********************9988764 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.0041
       SLIDE  43 ppsnkgkkeyteeeDrfllvllakyGygnyekikke 78 
                 +++ ++++ +t  eD++ll  +a +G++ +  i+++
  EEA19508.1 471 KSKRRSRRPFTPAEDEALLKGYAVHGFQ-WTLIQQD 505
                 456777888*****************98.8888775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (690 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       503  (0.0280551); expected 358.6 (0.02)
Passed bias filter:                      269  (0.0150036); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.55u 0.25s 00:00:00.80 Elapsed: 00:00:00.39
# Mc/sec: 5259.82
//
Query:       EEA19509.1  [L=155]
Description: hypothetical protein PMAA_003000 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
       0.22   11.9   0.1       0.33   11.3   0.1    1.3  1  Biliv-reduc_cat  Biliverdin reductase, catalytic


Domain annotation for each model (and alignments):
>> Biliv-reduc_cat  Biliverdin reductase, catalytic
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   1.9e-05      0.33      27      55 ..     123     151 ..     111     155 .] 0.84

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 1.9e-05
  Biliv-reduc_cat  27 kekfGfpafsgiarlsWlvdlfGelsvts 55 
                        ++Gf af  + r+++l+ lfG  + +s
       EEA19509.1 123 WGNIGFTAFLFVNRMAYLLGLFGSKTSKS 151
                      5689*******************977666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (155 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       331  (0.0184617); expected 358.6 (0.02)
Passed bias filter:                      225  (0.0125495); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.25s 00:00:00.63 Elapsed: 00:00:00.42
# Mc/sec: 1103.50
//
Query:       EEA19510.1  [L=1431]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.5e-74  245.9  18.7    1.1e-14   54.8   0.0    7.7  8  Ank_2            Ankyrin repeats (3 copies)
    2.6e-51  171.4  11.0    1.7e-08   34.8   0.3   10.4 11  Ank_4            Ankyrin repeats (many copies)
    1.3e-48  162.4  15.3    6.9e-08   32.6   0.3   11.6 12  Ank_5            Ankyrin repeats (many copies)
    2.3e-45  151.1  25.6    5.6e-08   32.9   0.2   13.0 11  Ank              Ankyrin repeat
    4.7e-38  124.9  16.2    2.2e-06   27.6   0.1   14.5 14  Ank_3            Ankyrin repeat
    5.3e-07   30.0   0.7    2.5e-06   27.8   0.0    2.5  3  AAA_22           AAA domain
    0.00028   20.6  10.7    0.00053   19.7  10.7    1.4  1  ZZ               Zinc finger, ZZ type
    0.00099   18.5   0.3     0.0024   17.3   0.3    1.7  1  Helo_like_N      Fungal N-terminal domain of STAND proteins
     0.0027   18.0   3.9     0.0055   17.0   3.9    1.5  1  C1_2             C1 domain
     0.0027   18.1   0.0      0.011   16.2   0.0    2.1  1  AAA_16           AAA ATPase domain
     0.0039   17.1   0.1      0.016   15.1   0.1    2.0  1  NACHT            NACHT domain
  ------ inclusion threshold ------
       0.11   10.5   0.2       0.16    9.9   0.2    1.2  1  Methyltrans_Mon  Virus-capping methyltransferase
       0.17   11.9   0.2       0.42   10.6   0.2    1.7  1  TM_helix         Conserved TM helix


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.9   0.0   2.2e-10   3.1e-07      24      83 .]     750     815 ..     723     815 .. 0.82
   2 !   39.3   0.2   5.5e-13   7.5e-10       1      81 [.     756     847 ..     756     849 .. 0.88
   3 !   40.0   0.0   3.1e-13   4.3e-10       8      83 .]     829     921 ..     822     921 .. 0.75
   4 !   54.8   0.0   7.9e-18   1.1e-14       1      78 [.     858     949 ..     858     953 .. 0.84
   5 !   43.2   0.2   3.2e-14   4.5e-11      23      83 .]     918     988 ..     911     988 .. 0.81
   6 !   39.2   0.0   5.7e-13   7.9e-10       1      74 [.     995    1080 ..     995    1088 .. 0.82
   7 !   47.7   0.8   1.3e-15   1.8e-12      15      81 ..    1144    1222 ..    1131    1224 .. 0.78
   8 !   21.5   0.0   1.9e-07   0.00026       7      76 ..    1238    1316 ..    1231    1323 .. 0.72

  Alignments for each domain:
  == domain 1  score: 30.9 bits;  conditional E-value: 2.2e-10
       Ank_2  24 kngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinlkd 83 
                 k+g + Lh+A + g +++v  L+e+       d +g tpL +Aa +g+ +++k+L+e ga++n  d
  EEA19510.1 750 KDGSSELHLASHLGLTKLVAELVEEgvnpdiKDANGVTPLVLAAVQGNVNVAKILIEAGASVNSVD 815
                 388999********99*******978665555588***************************9865 PP

  == domain 2  score: 39.3 bits;  conditional E-value: 5.5e-13
       Ank_2   1 LhlAakngnlelvklLl.egadpn.k..ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlek.gadinl 81 
                 LhlA+  g ++lv  L+ eg++p+ k  ng t+L +Aa +gn++++k+L+e+      +dn+g ++L+ A    +  +v+lL+e+ ++d+n+
  EEA19510.1 756 LHLASHLGLTKLVAELVeEGVNPDiKdaNGVTPLVLAAVQGNVNVAKILIEAgasvnsVDNTGCSVLYKATDLYQVAFVQLLVEQeDIDVNI 847
                 899999997789*****99999998458**********************9666766777***********99999*******775788886 PP

  == domain 3  score: 40.0 bits;  conditional E-value: 3.1e-13
       Ank_2   8 gnlelvklLl..egadpn..k...ngktaLhyAakngnleivklLleh.........adndgrtpLhyAarsghleivklLlek.gadinlkd 83 
                 ++  +v+lL+  e  d+n  +    + t+L+ Aa  g  eivklL++           +  g t+L+yAa  g l++vk+Ll + +++i+l+d
  EEA19510.1 829 YQVAFVQLLVeqEDIDVNiaHprqSDFTPLIRAAFDGFAEIVKLLVSVpqleinksgSEPAGATALIYAATAGTLDCVKILLSQpNVEIDLQD 921
                 455689999954445555762567899*******************944455444444477*********************44488887765 PP

  == domain 4  score: 54.8 bits;  conditional E-value: 7.9e-18
       Ank_2   1 LhlAakngnlelvklLl..egadpn...k..ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlekgad 78 
                 L+ Aa +g  e+vklL+     ++n   +   g taL+yAa +g l++vk+Ll++       +d+ g ++L+yAa++g++eiv+ Lle++a+
  EEA19510.1 858 LIRAAFDGFAEIVKLLVsvPQLEINksgSepAGATALIYAATAGTLDCVKILLSQpnveidlQDERGASALIYAAENGYTEIVEALLERDAN 949
                 67899999779******875566665442689*********************9777776666699*********************98665 PP

  == domain 5  score: 43.2 bits;  conditional E-value: 3.2e-14
       Ank_2  23 n.k..ngktaLhyAakngnleivklLleh......ad.ndgrtpLhyAarsghleivklLlekgadinlkd 83 
                 + +   g +aL+yAa+ng++eiv++Lle       ++  +  t+L+ A+ ++ + +vklLl++ga+++ kd
  EEA19510.1 918 DlQdeRGASALIYAAENGYTEIVEALLERdanteaLEvGTQGTALMRAIDYNAIPVVKLLLQHGANVHHKD 988
                 3423589********************9664444433544559************************9987 PP

  == domain 6  score: 39.2 bits;  conditional E-value: 5.7e-13
       Ank_2    1 LhlAakngnlelvklLl...egadpn.k..ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLle 74  
                  Lh Aa ng +e+++lLl      d+n +  ngkt Lh  a+ gn++++k Ll+h       d+ grtp+ +A + +h++i+++L e
  EEA19510.1  995 LHGAACNGRSEIIELLLefdPTLDINmQdvNGKTTLHDVARLGNENTAKVLLDHgadptiKDKFGRTPIRIAREVNHSKILQMLRE 1080
                  8999***9899******54333555563699******9999999999******99565544488********888999*9999975 PP

  == domain 7  score: 47.7 bits;  conditional E-value: 1.3e-15
       Ank_2   15 lLl..egadpn..k..ngktaLhyAakngnleivklLleh......adndgrtpLhyAars.ghleivklLlekgadinl 81  
                   L   ++ d+n  +   g+taLh+A++n+n+ei++ L++h       +n+grtpLh+Aa +  h ++ ++Ll+ ga++++
  EEA19510.1 1144 RLSkdFNEDINgkDpdMGETALHHAVSNDNEEIIRQLISHgadlnaKNNYGRTPLHLAALYvCH-KAGEILLDAGANVDA 1222
                  554343444444314499*********************99775544499**********9666.*******99**9986 PP

  == domain 8  score: 21.5 bits;  conditional E-value: 1.9e-07
       Ank_2    7 ngnlelvklLl..egadpn.k.ngktaLh.yAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekg 76  
                  n+  + ++ Ll   ga++  + + ++a   +A+  g+ ++v+ L+++       d +grtp ++A ++ h++i++lLle g
  EEA19510.1 1238 NY--SSLNVLLieRGAKLThEtTALNAYLeLAVVDGSADAVRRLVDAgadlwrKDWYGRTPFIIARSYEHEDIANLLLELG 1316
                  43..4677776676666653233334434467778**********977566555599********999**********876 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.0   1.7e-06    0.0024       5      55 .]     756     805 ..     752     805 .. 0.94
   2 !   18.2   0.0     2e-06    0.0028       3      42 ..     787     825 ..     785     826 .. 0.93
   3 !   12.6   0.0   0.00012      0.16      17      55 .]     834     874 ..     830     874 .. 0.88
   4 !   34.1   0.0   2.1e-11   2.9e-08       3      55 .]     892     944 ..     890     944 .. 0.97
   5 !   20.2   0.3   4.8e-07   0.00067       3      55 .]     960    1011 ..     958    1011 .. 0.92
   6 !    9.2   0.1    0.0014       1.9       8      40 ..     998    1031 ..     992    1038 .. 0.83
   7 !   24.4   0.0   2.3e-08   3.2e-05       3      54 ..    1028    1078 ..    1026    1079 .. 0.95
   8 !   14.7   0.0   2.6e-05     0.036      23      52 ..    1149    1178 ..    1140    1181 .. 0.83
   9 !   34.8   0.3   1.3e-11   1.7e-08       3      43 ..    1163    1202 ..    1161    1204 .. 0.95
  10 ?    0.3   0.0      0.84   1.2e+03      17      39 ..    1210    1231 ..    1206    1231 .. 0.84
  11 !   16.5   0.0   7.1e-06    0.0098       6      55 .]    1265    1313 ..    1260    1313 .. 0.89

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 1.7e-06
       Ank_4   5 LhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 Lh a + g ++lv+ L+e g++++   +++G t+l  Aa  gnv+++k L+
  EEA19510.1 756 LHLASHLGLTKLVAELVEEGVNPDIK-DANGVTPLVLAAVQGNVNVAKILI 805
                 899999999****************9.*********************997 PP

  == domain 2  score: 18.2 bits;  conditional E-value: 2e-06
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiA 42 
                 t+L  aa +g++ ++++L+e ga++n + ++ G + l++A
  EEA19510.1 787 TPLVLAAVQGNVNVAKILIEAGASVNSV-DNTGCSVLYKA 825
                 89999***********************.888***99998 PP

  == domain 3  score: 12.6 bits;  conditional E-value: 0.00012
       Ank_4  17 vrlLlek.gadinaqdnrs.GetalhiAakrgnveilklLl 55 
                 v+lL+e+ ++d+n   +r+ ++t+l++Aa  g+ ei+klL+
  EEA19510.1 834 VQLLVEQeDIDVNIAHPRQsDFTPLIRAAFDGFAEIVKLLV 874
                 899**9989**99997777477*****************96 PP

  == domain 4  score: 34.1 bits;  conditional E-value: 2.1e-11
       Ank_4   3 taLhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAakrgnveilklLl 55 
                 taL yaa +g l++v++Ll++ +++i+ q +++G +al++Aa +g+ ei++ Ll
  EEA19510.1 892 TALIYAATAGTLDCVKILLSQpNVEIDLQ-DERGASALIYAAENGYTEIVEALL 944
                 89*******************99******.**********************97 PP

  == domain 5  score: 20.2 bits;  conditional E-value: 4.8e-07
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  taL +a+ ++ +++v+lLl++ga++++  +  ++  lh Aa +g+ ei++lLl
  EEA19510.1  960 TALMRAIDYNAIPVVKLLLQHGANVHHK-DCFDRGMLHGAACNGRSEIIELLL 1011
                  8999***********************9.6667779999************98 PP

  == domain 6  score: 9.2 bits;  conditional E-value: 0.0014
       Ank_4    8 aaisgrlelvrlLlekg..adinaqdnrsGetalh 40  
                  aa  gr e+++lLle++   din+q + +G t lh
  EEA19510.1  998 AACNGRSEIIELLLEFDptLDINMQ-DVNGKTTLH 1031
                  4447999*********76799****.*******99 PP

  == domain 7  score: 24.4 bits;  conditional E-value: 2.3e-08
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54  
                  t+Lh  a  g++ +++ Ll++gad+    ++ G+t++ iA   ++ +il++L
  EEA19510.1 1028 TTLHDVARLGNENTAKVLLDHGADPTIK-DKFGRTPIRIAREVNHSKILQML 1078
                  68*************************9.***********999999999998 PP

  == domain 8  score: 14.7 bits;  conditional E-value: 2.6e-05
       Ank_4   23 kgadinaqdnrsGetalhiAakrgnveilk 52  
                  ++ din  d++ Getalh+A+++ n ei++
  EEA19510.1 1149 FNEDINGKDPDMGETALHHAVSNDNEEIIR 1178
                  566899999999**************9997 PP

  == domain 9  score: 34.8 bits;  conditional E-value: 1.3e-11
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAa 43  
                  taLh+a++  ++e++r L+++gad+na  n++G+t+lh Aa
  EEA19510.1 1163 TALHHAVSNDNEEIIRQLISHGADLNAK-NNYGRTPLHLAA 1202
                  89*************************9.**********98 PP

  == domain 10  score: 0.3 bits;  conditional E-value: 0.84
       Ank_4   17 vrlLlekgadinaqdnrsGetal 39  
                   ++Ll+ ga+++a  +  G t+l
  EEA19510.1 1210 GEILLDAGANVDAL-DQWGATPL 1231
                  578**********9.99999997 PP

  == domain 11  score: 16.5 bits;  conditional E-value: 7.1e-06
       Ank_4    6 hyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                    a+ +g  ++vr+L++ gad+ +  + +G+t+++iA + ++ +i+ lLl
  EEA19510.1 1265 ELAVVDGSADAVRRLVDAGADLWRK-DWYGRTPFIIARSYEHEDIANLLL 1313
                  557779999***************9.888********9999999999997 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.6   0.0   0.00039      0.54       2      49 ..     739     785 ..     738     785 .. 0.91
   2 !   25.8   0.0   6.8e-09   9.4e-06       1      54 [.     771     823 ..     771     825 .. 0.95
   3 !    6.6   0.0    0.0072        10       6      40 ..     842     879 ..     836     885 .. 0.71
   4 !   28.0   0.0   1.4e-09     2e-06      13      56 .]     887     931 ..     881     931 .. 0.96
   5 !   18.4   0.0   1.5e-06     0.002      10      43 ..     918     951 ..     917     957 .. 0.86
   6 !   16.8   0.1   4.5e-06    0.0062       1      42 [.     943     984 ..     943     988 .. 0.88
   7 !   14.9   0.1   1.8e-05     0.025      18      53 ..     993    1030 ..     979    1034 .. 0.82
   8 !   28.8   0.0   7.7e-10   1.1e-06       1      56 []    1010    1066 ..    1010    1066 .. 0.98
   9 !   29.0   0.2   6.9e-10   9.5e-07      16      56 .]    1161    1201 ..    1145    1201 .. 0.87
  10 !   32.6   0.3     5e-11   6.9e-08       1      55 [.    1180    1233 ..    1180    1233 .. 0.98
  11 !    9.1   0.0    0.0012       1.7       1      40 [.    1213    1251 ..    1213    1254 .. 0.86
  12 !   11.3   0.0   0.00025      0.34       1      56 []    1246    1300 ..    1246    1300 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00039
       Ank_5   2 lehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrG 49 
                 l+++  +  ++ ++g + Lh+A++ g   +v +L+++g++++++d++G
  EEA19510.1 739 LDND-GQSSWTGKDGSSELHLASHLGLTKLVAELVEEGVNPDIKDANG 785
                 6666.677799999*******************************987 PP

  == domain 2  score: 25.8 bits;  conditional E-value: 6.8e-09
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltald 54 
                 L+e+g ++++ +d +g+tpL +Aa +g+ +v+++L++ ga+ n  d+ G ++l 
  EEA19510.1 771 LVEEG-VNPDIKDANGVTPLVLAAVQGNVNVAKILIEAGASVNSVDNTGCSVLY 823
                 89999.*******************************************99886 PP

  == domain 3  score: 6.6 bits;  conditional E-value: 0.0072
       Ank_5   6 padvnrldgggn..tpLhvAakygaadvvrlLl.arga 40 
                 ++dvn   ++    tpL+ Aa  g a++v+lL+  +++
  EEA19510.1 842 DIDVNIAHPRQSdfTPLIRAAFDGFAEIVKLLVsVPQL 879
                 44444444444444******************966555 PP

  == domain 4  score: 28.0 bits;  conditional E-value: 1.4e-09
       Ank_5  13 dgggntpLhvAakygaadvvrlLl.argadlnltdsrGltaldlA 56 
                 ++ g t+L++Aa +g +d+v++Ll  +++ ++l+d+rG +al +A
  EEA19510.1 887 EPAGATALIYAATAGTLDCVKILLsQPNVEIDLQDERGASALIYA 931
                 68899**************************************98 PP

  == domain 5  score: 18.4 bits;  conditional E-value: 1.5e-06
       Ank_5  10 nrldgggntpLhvAakygaadvvrlLlargadln 43 
                 + +d++g ++L++Aa++g+ ++v+ Ll+r a++ 
  EEA19510.1 918 DLQDERGASALIYAAENGYTEIVEALLERDANTE 951
                 46789999*******************8887765 PP

  == domain 6  score: 16.8 bits;  conditional E-value: 4.5e-06
       Ank_5   1 Llehgpadvnrldgggn.tpLhvAakygaadvvrlLlargadl 42 
                 Lle++ a++ +l+ g + t+L+ A+ y+a +vv+lLl +ga+ 
  EEA19510.1 943 LLERD-ANTEALEVGTQgTALMRAIDYNAIPVVKLLLQHGANV 984
                 67887.888888888888*******************999986 PP

  == domain 7  score: 14.9 bits;  conditional E-value: 1.8e-05
       Ank_5   18 tpLhvAakygaadvvrlLl..argadlnltdsrGltal 53  
                    Lh Aa +g++++++lLl  ++ +d+n++d +G+t l
  EEA19510.1  993 GMLHGAACNGRSEIIELLLefDPTLDINMQDVNGKTTL 1030
                  57999999**************************7765 PP

  == domain 8  score: 28.8 bits;  conditional E-value: 7.7e-10
       Ank_5    1 Llehg.padvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56  
                  Lle +   d+n +d +g t Lh  a+ g+ + +++Ll++gad++++d+ G+t++ +A
  EEA19510.1 1010 LLEFDpTLDINMQDVNGKTTLHDVARLGNENTAKVLLDHGADPTIKDKFGRTPIRIA 1066
                  8999999***********************************************998 PP

  == domain 9  score: 29.0 bits;  conditional E-value: 6.9e-10
       Ank_5   16 gntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56  
                  g+t+Lh+A+++ + +++r L+ +gadln+++++G+t+l+lA
  EEA19510.1 1161 GETALHHAVSNDNEEIIRQLISHGADLNAKNNYGRTPLHLA 1201
                  66*************************************98 PP

  == domain 10  score: 32.6 bits;  conditional E-value: 5e-11
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldl 55  
                  L++hg ad+n+++++g tpLh+Aa y++    ++Ll+ ga+ ++ d +G t+l++
  EEA19510.1 1180 LISHG-ADLNAKNNYGRTPLHLAALYVCHKAGEILLDAGANVDALDQWGATPLEM 1233
                  899**.***********************************************96 PP

  == domain 11  score: 9.1 bits;  conditional E-value: 0.0012
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlarga 40  
                  Ll++g a+v++ld++g tpL + + ++++++  lL++rga
  EEA19510.1 1213 LLDAG-ANVDALDQWGATPLEMRSARNYSSLNVLLIERGA 1251
                  89***.**************99998888888777777775 PP

  == domain 12  score: 11.3 bits;  conditional E-value: 0.00025
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56  
                  L+e+g a + ++    n  L +A+  g+ad vr+L++ gadl  +d +G+t++ +A
  EEA19510.1 1246 LIERG-AKLTHETTALNAYLELAVVDGSADAVRRLVDAGADLWRKDWYGRTPFIIA 1300
                  66777.777777777788999********************************998 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.3   0.0   0.00055      0.76       1      31 [.     751     782 ..     751     783 .. 0.88
   2 !   21.7   0.0   1.4e-07    0.0002       1      32 []     784     816 ..     784     816 .. 0.96
   3 ?    6.1   0.0     0.012        17       3      22 ..     855     874 ..     854     883 .. 0.85
   4 !   11.0   0.0   0.00034      0.46       2      31 ..     890     921 ..     889     922 .. 0.80
   5 !   11.3   0.0   0.00027      0.37       2      30 ..     924     953 ..     923     955 .. 0.87
   6 !   19.0   0.3     1e-06    0.0014       4      32 .]     960     989 ..     960     989 .. 0.90
   7 ?    6.1   0.0     0.012        17       6      31 ..     995    1023 ..     994    1024 .. 0.69
   8 !   16.2   0.1   7.7e-06     0.011       1      32 []    1025    1057 ..    1025    1057 .. 0.93
   9 !   32.9   0.2     4e-11   5.6e-08       1      32 []    1160    1192 ..    1160    1192 .. 0.97
  10 !   18.4   0.3   1.5e-06    0.0021       1      31 [.    1193    1224 ..    1193    1225 .. 0.79
  11 ?    4.1   0.0     0.052        72       1      24 [.    1292    1316 ..    1292    1326 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00055
                 TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hGAnlnald 31 
                 dG + LHlA++ g +  + +L+  G n++++d
  EEA19510.1 751 DGSSELHLASHLGLTKLVAELVeEGVNPDIKD 782
                 56667*****99*9999999**88******99 PP

  == domain 2  score: 21.7 bits;  conditional E-value: 1.4e-07
                 TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hGAnlnaldn 32 
                 +G TPL lAa  g+++++k L+  GA++n++dn
  EEA19510.1 784 NGVTPLVLAAVQGNVNVAKILIeAGASVNSVDN 816
                 7*********99**********88*******98 PP

  == domain 3  score: 6.1 bits;  conditional E-value: 0.012
                 BBHHHHHHHHTT.HHHHHHHH CS
         Ank   3 nTPLHlAatngk.kriiklLL 22 
                 +TPL +Aa +++ ++i+klL+
  EEA19510.1 855 FTPLIRAA-FDGfAEIVKLLV 874
                 8*******.566699****98 PP

  == domain 4  score: 11.0 bits;  conditional E-value: 0.00034
                 SBBHHHHHHHHTTHHHHHHHH.T.TTSTTCBT CS
         Ank   2 GnTPLHlAatngkkriiklLL.h.GAnlnald 31 
                 G T+L +Aat g ++++k LL +   +++++d
  EEA19510.1 890 GATALIYAATAGTLDCVKILLsQpNVEIDLQD 921
                 78*******999999******55335566665 PP

  == domain 5  score: 11.3 bits;  conditional E-value: 0.00027
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTCB CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlnal 30 
                 G ++L +Aa ng ++i+++LL + An  al
  EEA19510.1 924 GASALIYAAENGYTEIVEALLeRDANTEAL 953
                 779******************666998775 PP

  == domain 6  score: 19.0 bits;  conditional E-value: 1e-06
                 BHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnlnaldn 32 
                 T+L++A+ ++   ++klLL hGAn++ +d+
  EEA19510.1 960 TALMRAIDYNAIPVVKLLLqHGANVHHKDC 989
                 9******777777******99*****9996 PP

  == domain 7  score: 6.1 bits;  conditional E-value: 0.012
                  HHHHHHHTTHHHHHHHH..TT.TSTTCBT CS
         Ank    6 LHlAatngkkriiklLL..hG.Anlnald 31  
                  LH Aa+ng  +ii+lLL  +   ++n++d
  EEA19510.1  995 LHGAACNGRSEIIELLLefDPtLDINMQD 1023
                  8845559*********9533223677666 PP

  == domain 8  score: 16.2 bits;  conditional E-value: 7.7e-06
                  TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank    1 dGnTPLHlAatngkkriiklLL.hGAnlnaldn 32  
                  +G T LH  a+ g+++ +k LL hGA+++++d+
  EEA19510.1 1025 NGKTTLHDVARLGNENTAKVLLdHGADPTIKDK 1057
                  79999**6699*******************995 PP

  == domain 9  score: 32.9 bits;  conditional E-value: 4e-11
                  TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank    1 dGnTPLHlAatngkkriiklLL.hGAnlnaldn 32  
                  +G T+LH A++n++++ii+ L+ hGA+lna++n
  EEA19510.1 1160 MGETALHHAVSNDNEEIIRQLIsHGADLNAKNN 1192
                  69*****************************98 PP

  == domain 10  score: 18.4 bits;  conditional E-value: 1.5e-06
                  TSBBHHHHHHHHTTHHHHHH....HH.TTTSTTCBT CS
         Ank    1 dGnTPLHlAatngkkriikl....LL.hGAnlnald 31  
                  +G+TPLHlAa +    +++     LL  GAn++ald
  EEA19510.1 1193 YGRTPLHLAALY----VCHKageiLLdAGANVDALD 1224
                  69********76....774336659966******98 PP

  == domain 11  score: 4.1 bits;  conditional E-value: 0.052
                  TSBBHHHHHHHHTTHHHHHHHH.TT CS
         Ank    1 dGnTPLHlAatngkkriiklLL.hG 24  
                  +G+TP  +A ++ +++i+ lLL  G
  EEA19510.1 1292 YGRTPFIIARSYEHEDIANLLLeLG 1316
                  69******999**********9524 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.0      0.14   1.9e+02       6      31 .]     756     780 ..     751     780 .. 0.91
   2 !   13.9   0.0   4.4e-05     0.061       1      30 [.     784     812 ..     784     813 .. 0.95
   3 ?   -1.5   0.0       4.7   6.5e+03      17      31 .]     833     847 ..     819     847 .. 0.82
   4 ?    4.8   0.0     0.041        56       4      30 ..     856     882 ..     854     883 .. 0.89
   5 !    7.5   0.0    0.0055       7.5       2      30 ..     890     918 ..     889     919 .. 0.90
   6 !   11.5   0.0   0.00027      0.37       2      28 ..     924     949 ..     923     952 .. 0.90
   7 !   16.5   0.0   6.4e-06    0.0089       4      31 .]     960     986 ..     957     986 .. 0.94
   8 ?    6.5   0.0     0.012        16       5      30 ..     994    1018 ..     991    1021 .. 0.81
   9 ?    6.2   0.0     0.014        19       1      30 [.    1025    1053 ..    1025    1054 .. 0.88
  10 ?    0.1   0.0       1.4   1.9e+03       2      21 ..    1059    1078 ..    1058    1082 .. 0.90
  11 !   27.6   0.1   1.6e-09   2.2e-06       2      31 .]    1161    1189 ..    1160    1189 .. 0.96
  12 !   13.7   0.1     5e-05     0.068       1      30 [.    1193    1221 ..    1193    1222 .. 0.94
  13 ?    1.5   0.0      0.49   6.8e+02       6      29 ..    1264    1286 ..    1260    1287 .. 0.90
  14 ?    5.4   0.0     0.025        35       1      26 [.    1292    1316 ..    1292    1319 .. 0.92

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.14
       Ank_3   6 LhlAarsgnleivkfLlenkgadvna 31 
                 LhlA + g +++v  L+e  g+++++
  EEA19510.1 756 LHLASHLGLTKLVAELVE-EGVNPDI 780
                 9*****************.7999985 PP

  == domain 2  score: 13.9 bits;  conditional E-value: 4.4e-05
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvn 30 
                 nG tpL lAa +gn++++k L+e  ga vn
  EEA19510.1 784 NGVTPLVLAAVQGNVNVAKILIE-AGASVN 812
                 799********************.8**999 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 4.7
       Ank_3  17 ivkfLlenkgadvna 31 
                  v++L+e+  +dvn+
  EEA19510.1 833 FVQLLVEQEDIDVNI 847
                 4999***99999996 PP

  == domain 4  score: 4.8 bits;  conditional E-value: 0.041
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadvn 30 
                 tpL +Aa  g  eivk+L+  +  ++n
  EEA19510.1 856 TPLIRAAFDGFAEIVKLLVSVPQLEIN 882
                 9******************98777776 PP

  == domain 5  score: 7.5 bits;  conditional E-value: 0.0055
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G t+L +Aa +g l+ vk Ll +++++++
  EEA19510.1 890 GATALIYAATAGTLDCVKILLSQPNVEID 918
                 89*******************98888776 PP

  == domain 6  score: 11.5 bits;  conditional E-value: 0.00027
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgad 28 
                 G ++L +Aa++g +eiv++Lle + a+
  EEA19510.1 924 GASALIYAAENGYTEIVEALLE-RDAN 949
                 889*******************.7776 PP

  == domain 7  score: 16.5 bits;  conditional E-value: 6.4e-06
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadvna 31 
                 t+L++A+ ++ +++vk+Ll+ +ga+v++
  EEA19510.1 960 TALMRAIDYNAIPVVKLLLQ-HGANVHH 986
                 9*******************.9***985 PP

  == domain 8  score: 6.5 bits;  conditional E-value: 0.012
       Ank_3    5 pLhlAarsgnleivkfLlenkgadvn 30  
                  +Lh Aa +g+ ei+++Lle + + ++
  EEA19510.1  994 MLHGAACNGRSEIIELLLE-FDPTLD 1018
                  68889**************.655544 PP

  == domain 9  score: 6.2 bits;  conditional E-value: 0.014
       Ank_3    1 nGetpLhlAarsgnleivkfLlenkgadvn 30  
                  nG t Lh +ar gn + +k Ll+ +gad+ 
  EEA19510.1 1025 NGKTTLHDVARLGNENTAKVLLD-HGADPT 1053
                  577778989******99******.9***85 PP

  == domain 10  score: 0.1 bits;  conditional E-value: 1.4
       Ank_3    2 GetpLhlAarsgnleivkfL 21  
                  G+tp+ +A + ++ +i+++L
  EEA19510.1 1059 GRTPIRIAREVNHSKILQML 1078
                  9**************99998 PP

  == domain 11  score: 27.6 bits;  conditional E-value: 1.6e-09
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvna 31  
                  Get+Lh+A++++n ei++ L+  +gad+na
  EEA19510.1 1161 GETALHHAVSNDNEEIIRQLIS-HGADLNA 1189
                  9*********************.9****96 PP

  == domain 12  score: 13.7 bits;  conditional E-value: 5e-05
       Ank_3    1 nGetpLhlAarsgnleivkfLlenkgadvn 30  
                  +G+tpLhlAa++ +++  + Ll+  ga+v+
  EEA19510.1 1193 YGRTPLHLAALYVCHKAGEILLD-AGANVD 1221
                  79**************9******.8**998 PP

  == domain 13  score: 1.5 bits;  conditional E-value: 0.49
       Ank_3    6 LhlAarsgnleivkfLlenkgadv 29  
                  L lA+  g+ + v+ L++  gad+
  EEA19510.1 1264 LELAVVDGSADAVRRLVD-AGADL 1286
                  6799**************.8*997 PP

  == domain 14  score: 5.4 bits;  conditional E-value: 0.025
       Ank_3    1 nGetpLhlAarsgnleivkfLlenkg 26  
                  +G+tp+ +A ++ + +i+ +Lle  g
  EEA19510.1 1292 YGRTPFIIARSYEHEDIANLLLE-LG 1316
                  79********************9.65 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0         5   6.9e+03      81     118 ..     103     141 ..      99     160 .. 0.72
   2 ?   -3.1   0.1       6.5   8.9e+03      76     101 ..     191     212 ..     164     221 .. 0.72
   3 !   27.8   0.0   1.8e-09   2.5e-06       4     117 ..     257     399 ..     254     411 .. 0.71

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 5
      AAA_22  81 aleqalraravielliiDEaqhlr..seealeeLrsllnl 118
                 al+ ++ ++++ + +i  E+q l+     +++e+ +l+n+
  EEA19510.1 103 ALQAQIANTQA-QDVIPGEMQSLFaaDTGIINEIENLVND 141
                 56666666666.6677789999887668888888888885 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 6.5
      AAA_22  76 eellealeqalraravielliiDEaq 101
                 + + + ++q  +a ++    +iDEaq
  EEA19510.1 191 HSMTQEIYQTTQAVKD----VIDEAQ 212
                 4555666666666666....999998 PP

  == domain 3  score: 27.8 bits;  conditional E-value: 1.8e-09
      AAA_22   4 tagilvvtGesGtGKTtllrrlleqldeeakaee...erpevvfvtlpsst.sskdllrellralglelka...................erlsseell 79 
                 + gi+++ G +G+GKT+l + + ++ld+    ++   +++ ++  +++ +   s+d+ + l + l++ + +                      s+eell
  EEA19510.1 257 ENGIMICPGIPGAGKTYLSAIVIDELDNLRRLNKeplKGAAILMLYCKWDDvHSQDIHSLLGSLLKQIAQRygikskdtlemftkhngvrTKPSREELL 355
                 789***********************9887777778755555533333333355555555555555444447778888999999999998888999999 PP

      AAA_22  80 ealeqalraravielliiDEaqhlr...s....eealeeLrslln 117
                 +al + l++  + ++++iD  + lr   +     e+l+ L+  +n
  EEA19510.1 356 SALDKELQNFPR-SFVVIDGLDELReedHrltlLEILNSLKAKVN 399
                 999999999999.***********864414334444444443344 PP

>> ZZ  Zinc finger, ZZ type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7  10.7   3.9e-07   0.00053       2      37 ..     417     453 ..     416     461 .. 0.85

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 3.9e-07
                 SS-EE-TTT-S..EESSEEEESSS..SS-EE-HHHHHH CS
          ZZ   2 hkkytCdgCseapligvRyhclrc..sdYDLCqsCfst 37 
                 ++ ++Cd C++    +  yhc  c  sdYDLCqsC   
  EEA19510.1 417 SNYVSCDLCGA-GDLPYQYHCYECnnSDYDLCQSCIDD 453
                 6789*******.999*********5568*******876 PP

>> Helo_like_N  Fungal N-terminal domain of STAND proteins
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.3   1.8e-06    0.0024       1     159 [.      54     212 ..      54     222 .. 0.79

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 1.8e-06
  Helo_like_N   1 adplsiasgvlalvtfalqssksLyetvksfrsrdktvreLkeeleaLeevLesLee.va.vaeeeselalLklpllrCgkaCkefeqvikkcskkss 96 
                  +dpls++++v a++t+a+q    L ++ +  +    +   L +e++ L   +++L+  +a +++++     ++    + + + +e e++++++ +k  
   EEA19510.1  54 MDPLSVSASVAAVATAAFQIIGYLSSVASGGK----DRLSLLNEITHLWLTITALQAqIAnTQAQDVIPGEMQSLFAADTGIINEIENLVNDLNGK-L 146
                  69*****************9888877665544....446788999999999999999755034445555688888999999999****99999998.4 PP

  Helo_like_N  97 ksrtsfrD.wakley..mggdindfketlagYKsTisiaLgdinlrkskvtaevleeykeliedtt 159
                  ksr+++     +l++   + d+ +  e +    +Ti+ aL++in  +++   ++ +  k++i +++
   EEA19510.1 147 KSRSGYGKiKQTLTWplTETDVLKVVEKIHRMQQTIQFALSQINHSMTQEIYQTTQAVKDVIDEAQ 212
                  56665544123344421459*************************999999999999999999886 PP

>> C1_2  C1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   3.9     4e-06    0.0055       5      47 .]     383     451 ..     380     451 .. 0.78

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 4e-06
        C1_2   5 HpLtls.......................kgedssesfnCsaCgrkidgffYsCseCd...fslhvrCa 47 
                 H+Ltl                        ++ ++s+  +C++Cg    +++Y+C eC+   + l+++C+
  EEA19510.1 383 HRLTLLeilnslkakvnfmvtsrplenivRHFNDSNYVSCDLCGAGDLPYQYHCYECNnsdYDLCQSCI 451
                 77777777777777777777777777776677788889*******9667779999995555*******6 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   7.6e-06     0.011      17     169 ..     251     402 ..     247     403 .. 0.66

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 7.6e-06
      AAA_16  17 ervrsgrpelvllsGesGvGKsslvrellralekd..........ggif.lrgkcdqlesaipysa.laqalareellrqllde...aesaeleawrek 100
                 + + +++ +++++ G +G GK+ l   + ++l              +i+ l++k+d+ +     s+ + ++l   +ll+q++++   ++++ le + ++
  EEA19510.1 251 REWIEHENGIMICPGIPGAGKTYLSAIVIDELDNLrrlnkeplkgAAILmLYCKWDDVH-----SQdIHSLL-G-SLLKQIAQRygiKSKDTLEMFTKH 342
                 566777789999**********9975555433322334455998424446********3.....33366677.7.888888888775444344555444 PP

      AAA_16 101 leealaavpelagaeasrllellkrll.allsrderplvlvlDdlqwadeaslql.laaLlrllesk.pllv 169
                    +++             +e+l ++l + l++  +   +v+D l+ ++e+++ l l ++l +l++k +++v
  EEA19510.1 343 NGVRTK-----------PSREELLSALdKELQN-FPRSFVVIDGLDELREEDHRLtLLEILNSLKAKvNFMV 402
                 444444...........4445555555333444.43489***********9999988888888777667765 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.1   1.2e-05     0.016       4     142 ..     262     417 ..     260     423 .. 0.65

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 1.2e-05
                 EEEC-TTTCHHHHHHHHHHHHCTS-SCCCC...-SEEEEEETT.TTTTS-...-HCHHHCCCCTS--SSS-C.......................CHHH CS
       NACHT   4 ilqGeaGsGKTtLlqklalawaegklpqga...fklvFflslr.elsrsgnarsladllfsqlpepaapvse.......................vwav 75 
                 i  G +G GKT+L + +++++   +  +++      +++l ++ ++ +s+++ sl   l +q  +  +  s+                           
  EEA19510.1 262 ICPGIPGAGKTYLSAIVIDELDNLRRLNKEplkGAAILMLYCKwDDVHSQDIHSLLGSLLKQIAQRYGIKSKdtlemftkhngvrtkpsreellsALDK 360
                 556889999999999999998775444444465455555555514445555555555555555555555555555688888888888855555554444 PP

                 HCCSCCCEEEEEE-STT-SS-TCH.........HHHHHCTTTTT--EEEEEEECCCHHHHCTTSSCE CS
       NACHT  76 llelperlLlilDglDelvtdlgqkekqpvrtlLselirkkllpeasllltvrpralrdleeqleea 142
                  l+++ r   ++DglDel+++++        tlL e+++  l  ++ +++t+rp     + + + ++
  EEA19510.1 361 ELQNFPRSFVVIDGLDELREEDHR------LTLL-EILNS-LKAKVNFMVTSRPLEN--IVRHFNDS 417
                 4555555669*********98888......5555.77776.88899******99665..66666655 PP

>> Methyltrans_Mon  Virus-capping methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.2   0.00012      0.16     434     517 ..     127     212 ..      95     229 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00012
                      --HHHHHHHHHHHHHHGGGTS-SS-EEEEEE-HHH.HHHSS.-HHHH---SEEEEEEEETTS-TT---EEEEEE------------ CS
  Methyltrans_Mon 434 tdiesiekielnvkdfvlsildeqgvLifktYgty.lveen.kkaidiLgrlfksvtlvqtelsssktseiYllfkklkklldeel 517
                       d+  i++ie +v+d   ++   +g+  +k  +t+ l e +  k+++ + r+ ++++    ++  s t eiY   + +k ++de  
       EEA19510.1 127 ADTGIINEIENLVNDLNGKLKSRSGYGKIKQTLTWpLTETDvLKVVEKIHRMQQTIQFALSQINHSMTQEIYQTTQAVKDVIDEAQ 212
                      577899**************99****9999999983555553599*************************************8765 PP

>> TM_helix  Conserved TM helix
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.2   0.00031      0.42      12      33 ..    1404    1425 ..    1403    1428 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00031
                  TTHSHHHHHHHHHHHHHHHHHH CS
    TM_helix   12 sflPnLvgAilILlvGwiiAkf 33  
                  ++ P++  Ail+L+v+ ++A +
  EEA19510.1 1404 TYFPKVASAILVLVVAILVALM 1425
                  699****************966 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1431 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       812  (0.0452898); expected 358.6 (0.02)
Passed bias filter:                      625  (0.0348597); expected 358.6 (0.02)
Passed Vit filter:                        70  (0.00390429); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 1.06u 0.31s 00:00:01.37 Elapsed: 00:00:00.49
# Mc/sec: 8829.12
//
Query:       EEA19511.1  [L=541]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.5e-10   39.7   0.2    1.2e-09   38.6   0.2    1.6  1  RasGEF    RasGEF domain


Domain annotation for each model (and alignments):
>> RasGEF  RasGEF domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.6   0.2   6.8e-14   1.2e-09       1     149 [.     373     519 ..     373     535 .. 0.77

  Alignments for each domain:
  == domain 1  score: 38.6 bits;  conditional E-value: 6.8e-14
      RasGEF   1 elAeqltlieaelfskikpeellgsawskedrspnve.aviarfnrlsnwvaseilseeslkkRakviekfikiakecrklnNfnslmailsaLqsspv 98 
                 +lA+ lt+ ++ +f +++ e+l++++        +++  + +r   l+  v  ++     + + +++i+  i+i +   +++N+ns++a + +Lq+ ++
  EEA19511.1 373 DLARSLTRSDQSMFAQLSREQLMDEQ-------NSITgVLHTRWYDLAMAVRDCCT---AMPEFVQLIQECIQILH---NMRNYNSTLALIHGLQHISI 458
                 69***************999999943.......23442235677778888888776...57899***********9...999***************** PP

      RasGEF  99 srL...........kktweavskkslktle.......eleelmspennfknyrealkssasskpciPfl 149
                 + L           +    + ++++ ++++       +++ l +++nn++ yr+a+k +    p iPfl
  EEA19511.1 459 NFLwvnsttaittpS----NTPSNQSQAVNvysltpqNVSYLSDSSNNYAPYRHAMKVT----PGIPFL 519
                 **9987655533331....3332222222255566668888***************977....669998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (541 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       488  (0.0272185); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 3477.85
//
Query:       EEA19512.1  [L=209]
Description: ribonuclease H1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      3e-22   79.3   0.2    4.5e-22   78.8   0.2    1.2  1  RNase_H     RNase H
    4.6e-07   29.7   0.0      0.027   14.3   0.0    2.3  2  RVT_3       Reverse transcriptase-like
  ------ inclusion threshold ------
       0.13   12.0   0.0       0.33   10.7   0.0    1.7  2  NTPase_I-T  Protein of unknown function DUF84


Domain annotation for each model (and alignments):
>> RNase_H  RNase H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.8   0.2   7.5e-26   4.5e-22       4     139 ..      38     186 ..      36     195 .. 0.76

  Alignments for each domain:
  == domain 1  score: 78.8 bits;  conditional E-value: 7.5e-26
                 EEEEEEEEEECTTTCE..EEEE.EECTT...E.EEEEEEC.CCCHHHHHHHHHHHHHHH.TT.SC.........SEEEEEES-HHHHHHHHCCCHHHHH CS
     RNase_H   4 vvvYtDGsclgnpgeg..gaga.vlykeg.ar.nisaple.eaqtnnraELsAvieaLk.alksd.........ekvniytDSkYvvkgitqwvhrwkk 86 
                 + +Y+DG c++n ++    a+a +++ ++  +  i+a++  +  tn+raE++A+i+aL+ al +           +v+i++DS+Y+v+ +++w+++w +
  EEA19512.1  38 MKIYVDGGCRRNGRSDavAAAAaCIK-NKwGKyRIRARYItDDPTNQRAEITAIIMALElALAKYkndldemplMDVEIFSDSRYAVNCMKTWIYKWCR 135
                 789*********55543333332553.4433347777776699****************9995556778898999999********************* PP

                 TTSSSETTSSBHTTHHHHHHHHHCHCSSE....EEEEE-SCCSSSTHHHHHHHHHHH CS
     RNase_H  87 nawkttseqkpvknkdlaellkelakkkk....vqlkwvkgHaGvpkgNemaDrlAk 139
                 n+w +++ + pv n+dl+e++++l +++k    v+ +w++      ++Ne aD + +
  EEA19512.1 136 NGWMNSAGN-PVANRDLIEEASDLDDQVKeigtVEYTWIPR-----SENEVADGACN 186
                 ***888777.****999999987765543333389999983.....46777776555 PP

>> RVT_3  Reverse transcriptase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   4.6e-06     0.027       3      58 ..      43     100 ..      41     128 .. 0.75
   2 !   13.5   0.0   7.6e-06     0.046      93     124 .]     157     188 ..     139     188 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 4.6e-06
       RVT_3   3 dgafk.kksgag..gagvvirdsnGevllagaeklqgkasveeAElqALlrGLqlalkl 58 
                 dg ++ ++++++  +a++ i ++ G++   ++  +++  +++ AE +A++++L+lal+ 
  EEA19512.1  43 DGGCRrNGRSDAvaAAAACIKNKWGKYRIRARY-ITDDPTNQRAEITAIIMALELALAK 100
                 666633445555327777777778876665554.69999*****************975 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 7.6e-06
       RVT_3  93 eirkllksfesvsvehipReqNrvAdalAkra 124
                 +  + +k+  +v+ ++ipR++N vAd +++ra
  EEA19512.1 157 DLDDQVKEIGTVEYTWIPRSENEVADGACNRA 188
                 555566778899*****************986 PP

>> NTPase_I-T  Protein of unknown function DUF84
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0      0.98   5.9e+03      67      88 ..      42      64 ..      31      71 .. 0.61
   2 ?   10.7   0.0   5.5e-05      0.33      37      60 ..     174     197 ..     158     203 .. 0.87

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 0.98
                EEEEEET.....TEEEEEE.EEE CS
  NTPase_I-T 67 lEgGveeleek.lldvawaavvd 88
                + gG+ + + +  ++ a a++ +
  EEA19512.1 42 VDGGCRRNGRSdAVAAAAACIKN 64
                56777776666444444444544 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 5.5e-05
                 -BSHHHHHHHHHHHHHHHHHHSTT CS
  NTPase_I-T  37 PmgdeetlkGAinRaknaleaaee 60 
                 P +++e+ +GA nRa  ale++++
  EEA19512.1 174 PRSENEVADGACNRAMDALEKENR 197
                 999*****************9763 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (209 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       637  (0.035529); expected 358.6 (0.02)
Passed bias filter:                      483  (0.0269396); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.43u 0.24s 00:00:00.67 Elapsed: 00:00:00.40
# Mc/sec: 1551.83
//
Query:       EEA19513.1  [L=261]
Description: 40S ribosomal protein S4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.2e-37  125.1   0.1    1.6e-36  124.1   0.1    1.6  1  Ribosomal_S4e  Ribosomal family S4e
    5.7e-25   86.7   0.1    9.9e-25   85.9   0.1    1.4  1  40S_S4_C       40S ribosomal protein S4 C-terminus
    2.5e-17   62.7   5.2    4.7e-17   61.8   5.2    1.5  1  RS4NT          RS4NT (NUC023) domain
    1.2e-06   28.2   0.0    2.2e-06   27.2   0.0    1.5  1  S4             S4 domain
    0.00015   21.6   2.9    0.00015   21.6   2.9    3.1  4  KOW            KOW motif


Domain annotation for each model (and alignments):
>> Ribosomal_S4e  Ribosomal family S4e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  124.1   0.1   4.3e-40   1.6e-36       1      75 []      95     169 ..      95     169 .. 0.99

  Alignments for each domain:
  == domain 1  score: 124.1 bits;  conditional E-value: 4.3e-40
                    TTEEEEEEE-TTSSEEEEEE-TTCCCEEEEEECEEEEECCCEEEEEETTS-EEEESSTT-STTEEEEEETTTTEE CS
  Ribosomal_S4e   1 tgenyrllydtkgrfalhkItseeakyKLcKikkkttvkkgipqlvthdGrtirypdpdikvnDtvkidleenkI 75 
                    tgen+rl+ydtkgrf++h+I++eea+yKL K+k+++++k+gip lvthd+rt+rypdp+ikvnDtvkidl ++kI
     EEA19513.1  95 TGENFRLIYDTKGRFTVHRIQAEEAEYKLGKVKRVQLGKGGIPFLVTHDARTVRYPDPLIKVNDTVKIDLATGKI 169
                    89************************************************************************9 PP

>> 40S_S4_C  40S ribosomal protein S4 C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.9   0.1   2.8e-28   9.9e-25       1      47 [.     212     257 ..     212     258 .. 0.97

  Alignments for each domain:
  == domain 1  score: 85.9 bits;  conditional E-value: 2.8e-28
                 -SSS-EEEEEGGGEEE--STTS-SS---SS-S----HHHHHHHHHHH CS
    40S_S4_C   1 DaaGntFATRlsNvFvIGkgnkpwvsLPkgkGiklsiaeerdkrlak 47 
                 Da +ntFATR sNvFvIG+ +kpw+sLPkgkG+klsiaeerd+r+a+
  EEA19513.1 212 DAVDNTFATRESNVFVIGQ-DKPWISLPKGKGVKLSIAEERDRRRAQ 257
                 9*****************7.9************************98 PP

>> RS4NT  RS4NT (NUC023) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.8   5.2   1.3e-20   4.7e-17       1      37 []       3      39 ..       3      39 .. 0.98

  Alignments for each domain:
  == domain 1  score: 61.8 bits;  conditional E-value: 1.3e-20
                -S----EETTTS-TTS---SSSSSEE----SSSS-TT CS
       RS4NT  1 rGpkkHLKrlaAPkhWpldkkegvfavkPspGPHklr 37
                rGpkkH Krl+AP hW+ldk++g++a++ s+GPHklr
  EEA19513.1  3 RGPKKHQKRLSAPAHWLLDKMSGTYAPRASAGPHKLR 39
                8**********************************97 PP

>> S4  S4 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.2   0.0   6.3e-10   2.2e-06       3      48 .]      44      90 ..      42      90 .. 0.94

  Alignments for each domain:
  == domain 1  score: 27.2 bits;  conditional E-value: 6.3e-10
                HHHHH.HHTTSSSSHHHHHHHHHTTTEEETTEEE--TT-EE-TTCEE CS
          S4  3 Ldkvl.arlglassrreArqlIehGrVlVNGkvvkdpsyrVkpgDvi 48
                L +++  rl++a   re + + +++ V+V+Gkv++dp ++ +++Dvi
  EEA19513.1 44 LIVFIrNRLKYALNGRETKAILMQRLVQVDGKVRTDPTFPAGFMDVI 90
                6778889**************************************98 PP

>> KOW  KOW motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.1       2.6   9.5e+03      19      26 ..      69      76 ..      68      79 .. 0.76
   2 ?   -1.1   0.1       0.6   2.2e+03      16      26 ..     123     133 ..     122     141 .. 0.76
   3 ?   -3.6   0.1       3.5   1.3e+04       2       7 ..     157     162 ..     156     163 .. 0.72
   4 !   21.6   2.9   4.2e-08   0.00015       5      32 .]     181     211 ..     178     211 .. 0.95

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 2.6
                EEEEETTT CS
         KOW 19 Vvkvdqhk 26
                 v+vd ++
  EEA19513.1 69 LVQVDGKV 76
                58888876 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.6
                 EEEEEEEETTT CS
         KOW  16 tGkVvkvdqhk 26 
                  GkV++v   k
  EEA19513.1 123 LGKVKRVQLGK 133
                 799*9998665 PP

  == domain 3  score: -3.6 bits;  conditional E-value: 3.5
                 TSEEEE CS
         KOW   2 GdhVkV 7  
                  d+Vk+
  EEA19513.1 157 NDTVKI 162
                 688887 PP

  == domain 4  score: 21.6 bits;  conditional E-value: 4.2e-08
                 EEESSSTTTTCEEEEEEEETTT...TEEEEE CS
         KOW   5 VkVvsGphkGktGkVvkvdqhk...vrVfvd 32 
                  +V++G+++G++G+++++++h    ++V+++
  EEA19513.1 181 AMVTGGRNMGRVGVITHRERHDggfNIVHIK 211
                 69**************************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (261 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       403  (0.0224776); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1779.72
//
Query:       EEA19514.1  [L=365]
Description: aspartate-semialdehyde dehydrogenase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.7e-35  121.7   0.0      5e-35  121.2   0.0    1.2  1  Semialdhyde_dhC  Semialdehyde dehydrogenase, dimerisation dom
    1.5e-29  102.9   0.0    3.6e-29  101.7   0.0    1.7  1  Semialdhyde_dh   Semialdehyde dehydrogenase, NAD binding doma


Domain annotation for each model (and alignments):
>> Semialdhyde_dhC  Semialdehyde dehydrogenase, dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.2   0.0   5.6e-39     5e-35       3     183 ..     166     345 ..     164     346 .. 0.95

  Alignments for each domain:
  == domain 1  score: 121.2 bits;  conditional E-value: 5.6e-39
                      HHHHCTT.EEEEEEEEEEEGGGCHHHHHHHHHHHHHHHHHSTTS.CTTTSSHHTTSEESTCSTBTTTTCHCBHHHHHHHHHHHHHCTESC..SE CS
  Semialdhyde_dhC   3 PLldalgelervivatyqavSGaGkkgvreLlkqvaelqrsdeakpgvfgvpiagNlipyidkeedkgepetreelkavaetkkilefte..kv 94 
                      +L +++g +e+v v t qavSGaG+                    pgv++++i++N+ip+i +eedk e+e +++l+ v+ + ++++ ++   v
       EEA19514.1 166 ALQAKFGAVEEVEVFTEQAVSGAGY--------------------PGVPSMDIMDNVIPFISGEEDKLENEAQKILGSVNAEATAFQEQSglRV 239
                      67788********************....................9*****************************************9999888 PP

                      EEEEEEESBSSEEEEEEEEEES.....SSHHHHHHHHHHHHCS.........TTEEEEESSHCHHSSHHHHTTC..SSSEEEEEEEEETTCTT. CS
  Semialdhyde_dhC  95 satcvrVPvlrGhseavtiklk.....lkdveveeveellaaa.........pevkvvvneeedrPtpaavagg..tnsvsVGRirkdemgde. 171
                       atc+rV+v++Gh++ v++++k     +++++v++++ +++++         pe ++vv +e+drP+p+++++   +++vsVGR+r+   g + 
       EEA19514.1 240 GATCTRVGVTDGHMAFVSLRFKnrdsiPSAEQVKQALREYQSEaqklgahsaPEHAIVVFDEPDRPQPRLDRNIsgGYAVSVGRVREGAPGGHf 333
                      8**********************99999999999999999999*****************************9999***********9988887 PP

                      EEEEEEEEETTT CS
  Semialdhyde_dhC 172 glklvvvgDNll 183
                       + + ++++N++
       EEA19514.1 334 DIRFACLSHNTV 345
                      899*******98 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.7   0.0     4e-33   3.6e-29       1     119 [.       9     133 ..       9     135 .. 0.98

  Alignments for each domain:
  == domain 1  score: 101.7 bits;  conditional E-value: 4e-33
                     EEEEETTTSHHHHHHHHHHHCTSSEEEEEEEESTTTTTSBHHHHSG......GGTTTECEBEEEGGGGGCTT-SEEEE-SCHHHHHHHHHHHHHT CS
  Semialdhyde_dh   1 kvaivGatGyvGqellrlLeehpevelvvllsssrsaGkklaeavk......aleegkdlkvedvdeeelkevdivflalpagvskelapklaea 89 
                     k +++GatG vGq+++ lL++hp++ l+ + +ssrsaGkk+++avk      + +e ++l+v+++++e+++++d+vf+ l+++++ +++ ++++a
      EEA19514.1   9 KCGVLGATGSVGQRFILLLADHPNLVLHKVGASSRSAGKKYKDAVKwkqampMSKELSELVVQECTAENFADCDLVFSGLDSDIAGDVEMQFIKA 103
                     579************************************************999***************************************** PP

                     TSEEEESSSTTTTSTTSEBE-HHHHGGGGG CS
  Semialdhyde_dh  90 gvkviDlssdfRlkddavyvlpevnreaik 119
                     ++ ++++++++R ++ +++v+p vn+++++
      EEA19514.1 104 EIPIFSNAKNYRKHPLVPLVVPTVNPSHLD 133
                     ***************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (365 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       448  (0.0249875); expected 358.6 (0.02)
Passed bias filter:                      424  (0.0236488); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 2417.94
//
Query:       EEA19515.1  [L=365]
Description: aspartate-semialdehyde dehydrogenase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.7e-35  121.7   0.0      5e-35  121.2   0.0    1.2  1  Semialdhyde_dhC  Semialdehyde dehydrogenase, dimerisation dom
    1.5e-29  102.9   0.0    3.6e-29  101.7   0.0    1.7  1  Semialdhyde_dh   Semialdehyde dehydrogenase, NAD binding doma


Domain annotation for each model (and alignments):
>> Semialdhyde_dhC  Semialdehyde dehydrogenase, dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.2   0.0   5.6e-39     5e-35       3     183 ..     166     345 ..     164     346 .. 0.95

  Alignments for each domain:
  == domain 1  score: 121.2 bits;  conditional E-value: 5.6e-39
                      HHHHCTT.EEEEEEEEEEEGGGCHHHHHHHHHHHHHHHHHSTTS.CTTTSSHHTTSEESTCSTBTTTTCHCBHHHHHHHHHHHHHCTESC..SE CS
  Semialdhyde_dhC   3 PLldalgelervivatyqavSGaGkkgvreLlkqvaelqrsdeakpgvfgvpiagNlipyidkeedkgepetreelkavaetkkilefte..kv 94 
                      +L +++g +e+v v t qavSGaG+                    pgv++++i++N+ip+i +eedk e+e +++l+ v+ + ++++ ++   v
       EEA19515.1 166 ALQAKFGAVEEVEVFTEQAVSGAGY--------------------PGVPSMDIMDNVIPFISGEEDKLENEAQKILGSVNAEATAFQEQSglRV 239
                      67788********************....................9*****************************************9999888 PP

                      EEEEEEESBSSEEEEEEEEEES.....SSHHHHHHHHHHHHCS.........TTEEEEESSHCHHSSHHHHTTC..SSSEEEEEEEEETTCTT. CS
  Semialdhyde_dhC  95 satcvrVPvlrGhseavtiklk.....lkdveveeveellaaa.........pevkvvvneeedrPtpaavagg..tnsvsVGRirkdemgde. 171
                       atc+rV+v++Gh++ v++++k     +++++v++++ +++++         pe ++vv +e+drP+p+++++   +++vsVGR+r+   g + 
       EEA19515.1 240 GATCTRVGVTDGHMAFVSLRFKnrdsiPSAEQVKQALREYQSEaqklgahsaPEHAIVVFDEPDRPQPRLDRNIsgGYAVSVGRVREGAPGGHf 333
                      8**********************99999999999999999999*****************************9999***********9988887 PP

                      EEEEEEEEETTT CS
  Semialdhyde_dhC 172 glklvvvgDNll 183
                       + + ++++N++
       EEA19515.1 334 DIRFACLSHNTV 345
                      899*******98 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.7   0.0     4e-33   3.6e-29       1     119 [.       9     133 ..       9     135 .. 0.98

  Alignments for each domain:
  == domain 1  score: 101.7 bits;  conditional E-value: 4e-33
                     EEEEETTTSHHHHHHHHHHHCTSSEEEEEEEESTTTTTSBHHHHSG......GGTTTECEBEEEGGGGGCTT-SEEEE-SCHHHHHHHHHHHHHT CS
  Semialdhyde_dh   1 kvaivGatGyvGqellrlLeehpevelvvllsssrsaGkklaeavk......aleegkdlkvedvdeeelkevdivflalpagvskelapklaea 89 
                     k +++GatG vGq+++ lL++hp++ l+ + +ssrsaGkk+++avk      + +e ++l+v+++++e+++++d+vf+ l+++++ +++ ++++a
      EEA19515.1   9 KCGVLGATGSVGQRFILLLADHPNLVLHKVGASSRSAGKKYKDAVKwkqampMSKELSELVVQECTAENFADCDLVFSGLDSDIAGDVEMQFIKA 103
                     579************************************************999***************************************** PP

                     TSEEEESSSTTTTSTTSEBE-HHHHGGGGG CS
  Semialdhyde_dh  90 gvkviDlssdfRlkddavyvlpevnreaik 119
                     ++ ++++++++R ++ +++v+p vn+++++
      EEA19515.1 104 EIPIFSNAKNYRKHPLVPLVVPTVNPSHLD 133
                     ***************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (365 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       448  (0.0249875); expected 358.6 (0.02)
Passed bias filter:                      424  (0.0236488); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.45
# Mc/sec: 2414.46
//
Query:       EEA19516.1  [L=580]
Description: oxidoreductase, FAD-binding [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.7e-66  224.5   0.0    2.4e-66  223.9   0.0    1.3  1  FAD-oxidase_C  FAD linked oxidases, C-terminal domain
    5.7e-34  116.8   0.0    1.2e-33  115.8   0.0    1.6  1  FAD_binding_4  FAD binding domain
  ------ inclusion threshold ------
      0.062   12.0   0.0       0.11   11.1   0.0    1.4  1  SepSecS        O-phosphoseryl-tRNA(Sec) selenium transferase,


Domain annotation for each model (and alignments):
>> FAD-oxidase_C  FAD linked oxidases, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  223.9   0.0   4.1e-70   2.4e-66       2     250 .]     308     551 ..     307     551 .. 0.97

  Alignments for each domain:
  == domain 1  score: 223.9 bits;  conditional E-value: 4.1e-70
                    -SEEEEEEEEESSHHHHHHHHHHHHHHT---SEEEEE-HHHHHHHHHTS-SSTTS-TTT-EEEEEEEEE-HHHHHHHHHHHHHHHTTT-EEEEE.. CS
  FAD-oxidase_C   2 pearavalvafpsfeaavkavreiaqagiipaalelmdkkaldlveatkgakkglpdeeealllvefegddeeeaeeelealveaileatgaadvl 97 
                    p + +v+ v+fp++++a++a+ +++++ i++ a+e+md+++++++++  g+  g  ++ee++l+++f+g+  +++   ++    +i++++  +++ 
     EEA19516.1 308 PDELRVGIVTFPTVRDAAAAAMQVIRKSIPVQAMEIMDEVQMNVINRAGGT--GRTWREEPTLFFKFSGTT-AQVADSIQ-NTKKIAQNNKSTSFE 399
                    677899*********************************************..******************.66666666.799************ PP

                    ........ETGGGGGGGGHHHHHHHHHCTTEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHEEEEEEEEEETTEEEEEEEEEEE..--TT--THHHH CS
  FAD-oxidase_C  98 vaqdeaeaealwkaRkaalpylrdallkagvavlseDtsvPvsrladlvrdikalldkyglevvlfgHagdgnlhlyilfdladeaeeeraeklvd 193
                    +a+d++ea alw aRk  l+  + al+ +g+ v+s+D++vP+srl+d++++ k+ l++ ++ +++ gH+gdgn+h  il+ +++++e er+ek+v+
     EEA19516.1 400 FAKDDQEAHALWSARKESLW-SNLALRPEGGEVWSTDVAVPLSRLPDIIEKSKEQLNELNIFASILGHIGDGNFHSSILYSRKNREETERVEKVVH 494
                    ********************.88899999******************************************************************* PP

                    HHHHHHHHTT-----------------------THHHHHHHHHHHH-TT--BSTT-- CS
  FAD-oxidase_C 194 evvdlavelgGsisgEHGvGldkkaylerekgeeglalmrriKaalDPkgiLNPgkv 250
                    ++vd+a+e++Gs++gEHG+Gl kk+yl +e g++++++mr++K+alDP++++NPgk+
     EEA19516.1 495 DMVDRAIEMDGSCTGEHGIGLGKKEYLIKELGPDTIDIMRSVKRALDPHWLMNPGKI 551
                    *******************************************************96 PP

>> FAD_binding_4  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.8   0.0     2e-37   1.2e-33       2     138 ..     135     270 ..     134     271 .. 0.96

  Alignments for each domain:
  == domain 1  score: 115.8 bits;  conditional E-value: 2e-37
                    EEEEEESSHHHHHHHHHHHHHCTSCEEEESSSTTEE.STTCSCCEEEEEETTS--EEEEETTTTEEEEETTSBHHHHHHHHHHHTTECSSGGGTTC CS
  FAD_binding_4   2 aavvrpeseeevaaalrlaneaglpvlvrGgGssll.gqavatggvvldlsrlnrileideeegtatveaGvtlgdlvealaakglllglepgsgi 96 
                     a+++p+s+eev+++ ++++++++p+++++gGssl    +   gg+++d+  +++ile+ +++  ++v++ +++ +l+ +la +gl+++++pg   
     EEA19516.1 135 VAIAYPRSTEEVSKIAKVCHKYRMPMVPYSGGSSLEaNFSAPYGGMTIDFAFMDKILEVHADDLDVVVQPSIPWMQLNSELAYTGLFFPVDPGP-- 228
                    589*********************************777779********88*************************************99987.. PP

                    GSBHHHTTTTT-EETTEEGG--HHGTEEEEEEEETTSEEEEE CS
  FAD_binding_4  97 pgtvGGaiatnagGygsekyGlirdnvlglevvladGevvrl 138
                    ++ +GG++ tn +G+++ +yG+++d+v +l+vvladG+v+++
     EEA19516.1 229 SAKIGGMVGTNCSGTNAVRYGTMKDWVINLTVVLADGRVIKT 270
                    588************************************997 PP

>> SepSecS  O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   1.9e-05      0.11     164     189 ..     136     161 ..      94     163 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 1.9e-05
                 STTTTB----HHHHHHHHHCCT--EE CS
     SepSecS 164 sffaprspDdvkeiakiCaeydvPhl 189
                  + +prs ++v +iak+C++y +P +
  EEA19516.1 136 AIAYPRSTEEVSKIAKVCHKYRMPMV 161
                 5679*******************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (580 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       576  (0.0321267); expected 358.6 (0.02)
Passed bias filter:                      458  (0.0255452); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.45
# Mc/sec: 3853.45
//
Query:       EEA19517.1  [L=1086]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
     0.0014   18.9  12.2     0.0014   18.9  12.2    4.2  4  ATG16          Autophagy protein 16 (ATG16)
  ------ inclusion threshold ------
        1.3    8.3  58.6      0.084   12.2  17.2    3.9  3  GAS            Growth-arrest specific micro-tubule binding
        8.4    6.8  11.8       0.54   10.6   1.3    4.2  4  TSC22          TSC-22/dip/bun family


Domain annotation for each model (and alignments):
>> ATG16  Autophagy protein 16 (ATG16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9  12.2   2.4e-07    0.0014      67     164 ..     544     659 ..     476     667 .. 0.77
   2 ?    2.1  13.4     0.033     2e+02     102     169 ..     675     742 ..     667     771 .. 0.88
   3 ?   -0.7  23.9      0.23   1.4e+03      17     150 ..     779     907 ..     770     928 .. 0.46
   4 ?   -4.8   0.8         3   1.8e+04      54      78 ..    1034    1058 ..    1023    1062 .. 0.42

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 2.4e-07
       ATG16  67 q..................snskqsakiqsleqklaqlreelaelyksrgelaqrllelneelqkleeklkedeerlaeleaeraaletklkdreeelr 147
                                      ++ +a +q+ e++++ + e la + ++r++l+q+l + +   q+lee++++ +e +++l+++  +   +++d   +  
  EEA19517.1 544 WrskvagllmdnarsshetIIQQMEAMLQDFENRCSNVEEPLALAVREREDLNQKLAASKHLNQQLEEQIQQSAEMMNALRKQLDESVAQIRDYSCQNV 642
                 0444444444444445444556789999*********************************************************************** PP

       ATG16 148 ekeklvqdlqDElsaLq 164
                  +++ v++lq El++ +
  EEA19517.1 643 HLANQVDALQTELDTSR 659
                 *************9976 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.033
       ATG16 102 qrllelneelqkleeklkedeerlaeleaeraaletklkdreeelrekeklvqdlqDElsaLqlqlnq 169
                 +r l+l+++++++++ l+e++ +++ +++er++l+++    +e+ +   +  +dl+ E+++Lq  ++q
  EEA19517.1 675 DRELDLMATVAERDDLLEEQQMEIEVMSKERTQLQEAAHVSAERHQAVPQDYDDLRQEMAQLQKDATQ 742
                 5668999*******************************************************977766 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 0.23
       ATG16  17 faeliqaynrLldrtsaleaenaklekaaasaks..sksskksakekeasasqsnskqsakiqsleqklaqlreelaelyksrgelaqrllelneelqk 113
                 +++l +  + L d++s le+ +++ e+++++ ++  +  +   +++ ++ +++ + +  +  ++ +q++ + r e ++l    + +++   ++++e+++
  EEA19517.1 779 NKDLQNENQMLKDKASNLEQAQSNWEQSMSALEEarQ--K--HKSSMADMETKYQDQVFEAQNQAQQLTERYRLEISTLRHDAANTSS---QAEKEIRT 870
                 3444444444555555555555555444444443211..1..1111111111111122223333334444455555555333333333...35555555 PP

       ATG16 114 leeklkedeerlaeleaeraaletklkdreeelreke 150
                 ++++++  e+++++ ++eraa  ++ ++ +e++    
  EEA19517.1 871 KNKRIQYLEKKVEAFRNERAAKAREFSEAQEHISRFM 907
                 5555555555555555555555555555555555555 PP

  == domain 4  score: -4.8 bits;  conditional E-value: 3
       ATG16   54 skksakekeasasqsnskqsakiqs 78  
                  +k++a+++++ a++++  q+++i+s
  EEA19517.1 1034 KKSPASTNPKDARNDKLGQQTQIES 1058
                  2233333333333333344444444 PP

>> GAS  Growth-arrest specific micro-tubule binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2  17.2   1.4e-05     0.084      29     166 ..     565     699 ..     558     701 .. 0.77
   2 ?    6.8   9.3   0.00064       3.8      87     162 ..     691     762 ..     681     767 .. 0.86
   3 ?    0.3  20.8     0.064   3.8e+02      92     200 .]     770     878 ..     747     878 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 1.4e-05
         GAS  29 kslKeeieelkkkeernekelseisqenkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkelekelkdlkwehevleqrfekvekerdelyk 127
                 +++   +++ +++    e  l+ +  e ++l+++L + ++ +++L++q+++  +    +++l+++l e+  +++d + ++  l  ++++++ e d+ +k
  EEA19517.1 565 QQMEAMLQDFENRCSNVEEPLALAVREREDLNQKLAASKHLNQQLEEQIQQSAE---MMNALRKQLDESVAQIRDYSCQNVHLANQVDALQTELDTSRK 660
                 444444444444555555555555555555555555555555555555555444...677899************************************ PP

         GAS 128 kfeaaiqevqqktglknllLekklkalqeelEkkeaqle 166
                 + ++ i+ v  k+  ++l L   +++ ++ lE+++ ++e
  EEA19517.1 661 EARDGIEMVNSKARDRELDLMATVAERDDLLEEQQMEIE 699
                 **********************************99986 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.00064
         GAS  87 lknlkarlkelekelkdlkwehevleqrfekvekerdelykkfeaaiqevqqktglknllLekklkalqeelEkke 162
                 l++++++++++ ke ++l++ ++v  +r ++v +++d+l+++  +  +++ q+ +    +L   +++lq+ +E +e
  EEA19517.1 691 LEEQQMEIEVMSKERTQLQEAAHVSAERHQAVPQDYDDLRQEMAQLQKDATQNFD----MLRHEITKLQQVMEIRE 762
                 789999***************************************9999999988....56677777777777665 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.064
         GAS  92 arlkelekelkdlkwehevleqrfekvekerdelykkfeaaiqevqqktglknllLekklkalqeelEkkeaqleev..laaanldpaalsavseklee 188
                 +r+  l +  kdl+ e+++l+++ +++e++  +++++  a ++e++qk +     +e+k +    e +++ +ql+e   l+ + l+ +++++ s++ e+
  EEA19517.1 770 NRIIALGETNKDLQNENQMLKDKASNLEQAQSNWEQSMSA-LEEARQKHKSSMADMETKYQDQVFEAQNQAQQLTERyrLEISTLR-HDAANTSSQAEK 866
                 46677778889***********************998765.*********************************996224455555.677888999*** PP

         GAS 189 vlesKnqeIkdL 200
                  +++Kn++I+ L
  EEA19517.1 867 EIRTKNKRIQYL 878
                 *********987 PP

>> TSC22  TSC-22/dip/bun family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.8      0.52   3.1e+03      25      44 ..     594     613 ..     583     635 .. 0.53
   2 ?   -1.6   0.0      0.59   3.5e+03      16      42 ..     620     646 ..     613     658 .. 0.76
   3 ?   -0.6   0.1      0.29   1.8e+03      17      35 ..     745     763 ..     741     770 .. 0.80
   4 ?   10.6   1.3     9e-05      0.54      21      53 ..     770     800 ..     760     805 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.52
       TSC22  25 eLeernseleeENslLkala 44 
                 +L ++ ++ ++ N++L +++
  EEA19517.1 594 DLNQKLAASKHLNQQLEEQI 613
                 34444444444444444333 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.59
       TSC22  16 VevLkekIkeLeernseleeENslLka 42 
                  + L+++  e +++++ +  +N  L +
  EEA19517.1 620 MNALRKQLDESVAQIRDYSCQNVHLAN 646
                 567888888888888888888877754 PP

  == domain 3  score: -0.6 bits;  conditional E-value: 0.29
       TSC22  17 evLkekIkeLeernselee 35 
                 ++L+ +I+ L++ ++  e+
  EEA19517.1 745 DMLRHEITKLQQVMEIRES 763
                 89********988766555 PP

  == domain 4  score: 10.6 bits;  conditional E-value: 9e-05
       TSC22  21 ekIkeLeernseleeENslLkalaspeqleqls 53 
                 ++I  L e+n+ l++EN++Lk  as+  leq++
  EEA19517.1 770 NRIIALGETNKDLQNENQMLKDKASN--LEQAQ 800
                 57999****************99986..55554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1086 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2411  (0.134475); expected 358.6 (0.02)
Passed bias filter:                      437  (0.0243739); expected 358.6 (0.02)
Passed Vit filter:                       112  (0.00624686); expected 17.9 (0.001)
Passed Fwd filter:                        57  (0.00317921); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 1.64u 0.40s 00:00:02.04 Elapsed: 00:00:00.61
# Mc/sec: 5356.50
//
Query:       EEA19518.1  [L=1359]
Description: RNA-directed RNA polymerase (Sad-1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   3.4e-194  646.8   0.0   4.6e-194  646.4   0.0    1.2  1  RdRP             RNA dependent RNA polymerase
      0.006   16.5   0.0      0.014   15.3   0.0    1.5  1  Xol-1_GHMP-like  Switch protein XOL-1, GHMP-like


Domain annotation for each model (and alignments):
>> RdRP  RNA dependent RNA polymerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  646.4   0.0  5.1e-198  4.6e-194       1     586 []     520    1097 ..     520    1097 .. 0.94

  Alignments for each domain:
  == domain 1  score: 646.4 bits;  conditional E-value: 5.1e-198
        RdRP    1 vtptriilegpeleksnrvlRrfkegsdrFlrvkfpdedge.rldse..dgeellkervkkvlkegiviagrkfeflafsdsqlrehsvwffapfee 94  
                  vtp++i+ ++p++e +nrvlRr++e++drFlrv+f+de+ e r++s+  d++++++ r+k+++++gi +++rk+eflaf +sq+reh+++ffa+   
  EEA19518.1  520 VTPSTIYWNTPSMEITNRVLRRYSEHADRFLRVRFKDEKFEgRINSThhDTMDEIFARIKRTMSNGIILGDRKYEFLAFGNSQFREHGAYFFAS--- 613 
                  79******************************************9999888*****************************************94... PP

        RdRP   95 egerisaeeirkwlgdfenisqsvaKyaaRlglalSttrptvvkvereqiiieeidDv.kneekdiylftDGvGliSrelarkiakklglkk.aeel 189 
                   + +++a +ir+w+g+f++i +++aKyaaRlg+++Sttr+   +     +  ++i+Dv +      y+f+DGvG+iSr la++ +++l++k+ ++e 
  EEA19518.1  614 -EAHVTAANIRAWMGEFSEI-RNIAKYAARLGQCFSTTRAI--N--TCTVELKRIPDVeRG----GYTFSDGVGRISRFLAQMTQQELKIKTpDKEP 700 
                  .4579************999.*******************3..3..22344789***9444....49***********************999889* PP

        RdRP  190 PsafQiRigGaKGvlavdkrlkp.ekielrpSqiKfkseeddsekrtleivkvsskpkpayLnrqlikiLedlgvpeevflellkealeelrealkd 285 
                  Psa+Q+R+gG+KG+l++++   + ++i++rpSq Kf +++     + lei+++s+++ +a+Lnrqli++L++lgv +evf+e l++++++l+ea++d
  EEA19518.1  701 PSAYQFRLGGCKGMLVLSDVP-RgREIQIRPSQEKFPANH-----QGLEIIRWSQFS-SATLNRQLIAVLSSLGVSDEVFHEKLRRMVSNLEEATRD 790 
                  ******************555.3478**********6554.....55**********.*************************************** PP

        RdRP  286 agaaaellkkagdpskleellaelldsgfdpseldpflrsllkalvkeslrklkekarIpvpksatllgvaDetgvLk................... 363 
                   +aa++ll+k++dp++++ +l+++++ gf +s  dpf++s+++ + ++s++ lkeka+I+++++a+llgv+Det++L+                   
  EEA19518.1  791 DRAAMRLLQKYIDPNEMTLVLSKMVSDGFLQS-RDPFVTSIITLWKAWSIKYLKEKAKITIEDGACLLGVLDETATLQgfsyekvkkphlsreskld 886 
                  *****************************666.57************************************************************** PP

        RdRP  364 .egevfvqlsealdqedeksktkllkgdvlVtRnPalhpgDiqvvkavdvpelrhlkdviVFstkGdrslaselsGGDlDGDkywViwdpelefapa 459 
                    +e+f+q+ +a     +++k+ ++kg ++++RnP+lhpgDi+vv+avd pel+hlkdv+V+++ Gdr++as++sGGDlDGD+y+Viwd++l   p 
  EEA19518.1  887 aLPEIFLQVYRA-----DEKKYCVIKGVCILARNPSLHPGDIRVVRAVDRPELAHLKDVVVLPQLGDRDIASMCSGGDLDGDDYLVIWDKDLV--P- 975 
                  ******999765.....3346999*9**********************99*****************************************96..5. PP

        RdRP  460 kpsneepadyeea.kpkeldrevtvediadffveymksdvlGlisnahlaiadq.eegiddpkclkLaelhskaVDypKtGipvdkkeiprelkkpk 554 
                  +++++ p+dy  + k ++ldr+vtv+di+ ffv+ymk+d+l +i++ahla++d   +g+++pkc++La+lhs+aVDy+KtG p+    +pr+l +p+
  EEA19518.1  976 NQWFRAPMDYA-PiKGVNLDRSVTVNDITTFFVNYMKNDSLPRIAHAHLAWSDFlMNGVESPKCIRLAQLHSNAVDYNKTGEPAY---LPRDL-RPR 1067
                  48999******.99***********************************************************************...****9.799 PP

        RdRP  555 ekPdfkekekkekakkpyykskkilgkLyrev 586 
                  ++P+f+ek+   k+k ++y+skkilg+Ly++v
  EEA19518.1 1068 RWPHFMEKNY--KPKDQTYQSKKILGQLYDAV 1097
                  9*****8885..56789************986 PP

>> Xol-1_GHMP-like  Switch protein XOL-1, GHMP-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   1.6e-06     0.014      48     164 ..    1086    1209 ..    1048    1231 .. 0.70

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 1.6e-06
                       HHHHHHHHHHHTT-TTS-GGGSHHHHHHHH.HHHHCC-T.T----HHHHHHHHHHHHHHHH-TTEEEEEE-SS-EE..EEEETTGGG-HHH. CS
  Xol-1_GHMP-like   48 klkklrdaynneeieetfpdilvpayieay.sknrvrre.dytdlekefdsqvaleklvnegeqveGfevvqGGil..valkkdsyfddel. 134 
                         k l++ y+  + ++  pd  vp       s   v  +      e  +d ++al++++ ++e  + fev    +l   +l+kd  f +el 
       EEA19518.1 1086 SKKILGQLYDAVDRVDFHPDFDVPFDKRVLeSGVSVTDNiMQFARELKVDYDLALKRIMAQHEIRTEFEVWSTFVLshANLSKDYKFHEELg 1177
                       34789999999999999999999976544313333322202222334455566***********************6667999998999983 PP

                       .HH.HHHHHHHHH-SS---EEEEEEE-B-B-- CS
  Xol-1_GHMP-like  135 .le.kvavavakeskekvsevsfdllklagga 164 
                        +   +  +  ke+ +kv+   f+ +k  + a
       EEA19518.1 1178 gITkALKERFQKECYDKVGGRDFNHIKPMAVA 1209
                       322123446789************99865544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1359 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1131  (0.0630822); expected 358.6 (0.02)
Passed bias filter:                      712  (0.0397122); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.99u 0.38s 00:00:01.37 Elapsed: 00:00:00.52
# Mc/sec: 7907.74
//
Query:       EEA19519.1  [L=369]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-10   41.1   0.0    7.5e-06   25.6   0.0    2.2  2  ELP6      Elongation complex protein 6
  ------ inclusion threshold ------
       0.13   11.2   0.2       0.17   10.8   0.2    1.1  1  Nro1      Nuclear pore complex subunit Nro1


Domain annotation for each model (and alignments):
>> ELP6  Elongation complex protein 6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.0   4.4e-06     0.039      45      92 ..      69     116 ..      66     129 .. 0.88
   2 !   25.6   0.0   8.3e-10   7.5e-06     105     234 ..     191     333 ..     172     347 .. 0.72

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 4.4e-06
        ELP6  45 gckvvfvalvqsfsHysivaqkLGvsLtqakekgqlvFleGLkesldv 92 
                   +vv+v++++ +  ++  +++LG++L+   e ++l+F++GL    d+
  EEA19519.1  69 AKRVVLVSFLRDWLFWRGEGKRLGLDLQRFVEGNRLRFVDGLSGLFDA 116
                 468***************************************987765 PP

  == domain 2  score: 25.6 bits;  conditional E-value: 8.3e-10
        ELP6 105 alkfldesnaasLkslyefvksalkesedgeeewkppvllvDdlsvLlsl..gvsaaavldFihyCratvcsklk..gnvvvlvradeeeedeeee... 196
                 al+ l+++  + +ks+ +   ++ + +e+ e+++   +l++D+ + +l    g++a+++++++   ++ v+s +        l+++ +  + +++    
  EEA19519.1 191 ALNQLENDILSVIKSFPNPNATNETGEEEEEDDEDDILLILDQPDLILATtpGIDANDMSEWVMGLQQHVLSTIIttSADTPLIHNANPYTANDSTatp 289
                 55555555555555555444444555555557888889999**9*9999888************99999999876332233456655544444433456 PP

        ELP6 197 ......lllkslkHqsslalkveGLatGyckdvHGqlevlwrrr 234
                        ++ +l+H ++++l+++ L+tG +kdv G l++++   
  EEA19519.1 290 leknhaSFVVGLAHRADMVLQLRTLDTGAAKDVSGVLRISRGGG 333
                 666677999******************************98765 PP

>> Nro1  Nuclear pore complex subunit Nro1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.2   1.9e-05      0.17     206     248 ..     192     234 ..     166     278 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 1.9e-05
        Nro1 206 vLqaldDlLdivdnfgkeeeeeeeldsddedeeeeveLeeeHP 248
                 + q+ +D+L++++ f + ++++e  ++++ed+e+++ L  + P
  EEA19519.1 192 LNQLENDILSVIKSFPNPNATNETGEEEEEDDEDDILLILDQP 234
                 334458******************999999****999877766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (369 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       436  (0.0243181); expected 358.6 (0.02)
Passed bias filter:                      367  (0.0204696); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.30s 00:00:00.82 Elapsed: 00:00:00.47
# Mc/sec: 2384.74
//
Query:       EEA19520.1  [L=93]
Description: 60S ribosomal protein L37 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.5e-29  100.1  12.9    8.1e-29   99.6  12.9    1.3  1  Ribosomal_L37e  Ribosomal protein L37e
     0.0069   16.4   1.9      0.011   15.8   1.9    1.2  1  DZR             Double zinc ribbon
  ------ inclusion threshold ------
      0.071   13.0   2.4       0.13   12.2   2.4    1.4  1  DUF35_N         Rubredoxin-like zinc ribbon domain (DUF35_N)
       0.12   12.5   1.0       0.15   12.1   1.0    1.2  1  HypA            Hydrogenase/urease nickel incorporation, meta
       0.18   11.6   3.9        6.3    6.7   0.5    2.3  2  zinc_ribbon_2   zinc-ribbon domain
       0.19   11.2   3.8       0.67    9.4   3.8    1.8  1  zf-ribbon_3     zinc-ribbon domain
          1    8.9   5.7        2.7    7.5   2.8    2.1  2  DUF2688         Protein of unknown function (DUF2688)
        4.6    7.1  10.7        9.2    6.1   5.7    3.0  3  zf-HYPF         HypF finger


Domain annotation for each model (and alignments):
>> Ribosomal_L37e  Ribosomal protein L37e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.6  12.9   3.6e-32   8.1e-29       1      54 []       2      54 ..       2      54 .. 0.98

  Alignments for each domain:
  == domain 1  score: 99.6 bits;  conditional E-value: 3.6e-32
  Ribosomal_L37e  1 tkGtssfGkrqkkktHilCrrCgkrsyhvqkktCascGypsaklrkynWsaKak 54
                    tkGtssfGkr ++ktH+lCrrCgkrs+h+qk+tCa+cGyp+ak+rkynWs+Kak
      EEA19520.1  2 TKGTSSFGKR-HNKTHTLCRRCGKRSFHIQKSTCANCGYPAAKTRKYNWSEKAK 54
                    8*********.*****************************************96 PP

>> DZR  Double zinc ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   1.9   4.7e-06     0.011       8      42 ..      12      45 ..       8      48 .. 0.75

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 4.7e-06
         DZR  8 lppdarfCseCgtk...lkavaaedrCpsCgekvdpea 42
                +++    C +Cg++   ++    + +C +Cg+++ ++ 
  EEA19520.1 12 HNKTHTLCRRCGKRsfhIQ----KSTCANCGYPAAKTR 45
                5566779999999955444....899****99987665 PP

>> DUF35_N  Rubredoxin-like zinc ribbon domain (DUF35_N)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   2.4   5.8e-05      0.13      14      32 ..      19      38 ..      17      39 .. 0.96

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 5.8e-05
     DUF35_N 14 CpdCGtvqfPPr.avCphCg 32
                C+ CG+  f  +   C +Cg
  EEA19520.1 19 CRRCGKRSFHIQkSTCANCG 38
                *******************8 PP

>> HypA  Hydrogenase/urease nickel incorporation, metallochaperone, hypA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   1.0   6.8e-05      0.15      67      97 ..      13      42 ..       4      48 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 6.8e-05
                E--EEEETTTS-EEECHHHHHS-TTTSSS-E CS
        HypA 67 vpvkvrCreCgkefeleekalrCpkCgsadv 97
                 + ++ Cr+Cgk+  + +k  +C +Cg    
  EEA19520.1 13 NKTHTLCRRCGKRSFHIQK-STCANCGYPAA 42
                677899*****98875533.58****98765 PP

>> zinc_ribbon_2  zinc-ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.2    0.0046        10       6      21 ..       9      24 ..       9      25 .. 0.76
   2 ?    6.7   0.5    0.0028       6.3      16      22 ..      34      40 ..      31      42 .. 0.82

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.0046
  zinc_ribbon_2  6 GaelqdnakFCpyCGt 21
                   G+ + ++ + C +CG 
     EEA19520.1  9 GKRHNKTHTLCRRCGK 24
                   6777778888999985 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0028
  zinc_ribbon_2 16 CpyCGtp 22
                   C +CG+p
     EEA19520.1 34 CANCGYP 40
                   8899987 PP

>> zf-ribbon_3  zinc-ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   3.8    0.0003      0.67       5      25 ..      19      40 ..      15      40 .. 0.90

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0003
  zf-ribbon_3  5 CPnCGa.plssddnvCpyCGtk 25
                 C +CG+     + ++C++CG++
   EEA19520.1 19 CRRCGKrSFHIQKSTCANCGYP 40
                 77899999999*********96 PP

>> DUF2688  Protein of unknown function (DUF2688)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   2.8    0.0012       2.7       8      22 ..      17      31 ..      13      33 .. 0.76
   2 ?    3.0   0.1      0.03        68       5      22 ..      29      46 ..      25      50 .. 0.81

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0012
     DUF2688  8 TqCrRCGkslstlsr 22
                T CrRCGk    +++
  EEA19520.1 17 TLCRRCGKRSFHIQK 31
                88*****97655555 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.03
     DUF2688  5 iVtTqCrRCGkslstlsr 22
                i    C  CG +  ++++
  EEA19520.1 29 IQKSTCANCGYPAAKTRK 46
                55678******9999986 PP

>> zf-HYPF  HypF finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   1.0      0.12   2.7e+02      17      28 ..      12      23 ..       7      26 .. 0.73
   2 ?    6.1   5.7    0.0041       9.2      14      28 ..      24      38 ..      18      41 .. 0.90
   3 ?    0.6   0.1      0.22   4.9e+02       9      18 ..      66      75 ..      65      79 .. 0.77

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.12
                TT-TT---TTTS CS
     zf-HYPF 17 fhaqfisCtnCG 28
                ++   + C +CG
  EEA19520.1 12 HNKTHTLCRRCG 23
                555567799998 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.0041
                STTTT-TT---TTTS CS
     zf-HYPF 14 dRRfhaqfisCtnCG 28
                 R fh+q  +C nCG
  EEA19520.1 24 KRSFHIQKSTCANCG 38
                588***********9 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.22
                HC-TTSTTTT CS
     zf-HYPF  9 ykdpldRRfh 18
                y    dRRf+
  EEA19520.1 66 YLKTVDRRFQ 75
                556789***7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (93 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       814  (0.0454013); expected 358.6 (0.02)
Passed bias filter:                      424  (0.0236488); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.42u 0.28s 00:00:00.70 Elapsed: 00:00:00.45
# Mc/sec: 623.86
//
Query:       EEA19521.1  [L=414]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (414 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1838  (0.102515); expected 358.6 (0.02)
Passed bias filter:                      352  (0.019633); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.64u 0.32s 00:00:00.96 Elapsed: 00:00:00.53
# Mc/sec: 2342.28
//
Query:       EEA19522.1  [L=144]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-19   71.1   0.4    1.6e-19   70.8   0.4    1.1  1  EthD      EthD domain
  ------ inclusion threshold ------
      0.021   15.3   0.4       0.12   12.8   0.4    2.0  1  MmlI      Methylmuconolactone methyl-isomerase


Domain annotation for each model (and alignments):
>> EthD  EthD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.8   0.4   1.8e-23   1.6e-19       2      94 .]      15     128 ..      14     128 .. 0.95

  Alignments for each domain:
  == domain 1  score: 70.8 bits;  conditional E-value: 1.8e-23
                 -S-HHHHHHHHHHTHHHHHCTSTT...............................--EEEEEEEEEBTTC--SEEEEEEEEE...SSHHHHHHHHCSHH CS
        EthD   2 glspeeFrdyweevHaplvkdllg.....g.irryvlr.............atktrpateagvalagpgsdadyDgiaelwf...dsleaflaafadpe 78 
                 gls e+F+++ ee H+ l k+l g     +  r+y++r             + ++r+at+++++ ag++sd+d+D+ ael+f   + +++f a  ++pe
  EEA19522.1  15 GLSLEDFKKHCEE-HVLLIKRLTGddfplShKRHYIARnalssdesqnnntTVTERNATTPAIVFAGQQSDFDFDAYAELTFasqEAFQTFIAKIQTPE 112
                 9************.***************88999**99************9999****************************77778888889999*** PP

                 HHH.HHHHHHHHCGGX CS
        EthD  79 yaavlaaDeenFaDks 94 
                 +aa++aaDee+F+D+s
  EEA19522.1 113 IAAQIAADEERFLDRS 128
                 **************86 PP

>> MmlI  Methylmuconolactone methyl-isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.4   1.4e-05      0.12       9      84 ..      11     107 ..       4     134 .. 0.58

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.4e-05
        MmlI   9 srredlsheqflahwrevhaplvhavtG.......lrryqqnrvvder...........ftqfvPv..........veydgypvdgivelWfedlasle 79 
                  r+ +ls e+f +h+ e h  l   +tG        r y+ ++                                  + d +++d+ +el f+  ++++
  EEA19522.1  11 YRKAGLSLEDFKKHCEE-HVLLIKRLTGddfplshKRHYIARNALSSDesqnnnttvteR-----NattpaivfagQQSD-FDFDAYAELTFASQEAFQ 102
                 5999***********99.******999955443323556666554443444444444442.....033333333321122.446777777777777666 PP

        MmlI  80 ksfas 84 
                   +a 
  EEA19522.1 103 TFIAK 107
                 54442 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (144 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       535  (0.0298399); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.32s 00:00:00.90 Elapsed: 00:00:00.55
# Mc/sec: 790.82
//
Query:       EEA19523.1  [L=460]
Description: mRNA splicing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    6.6e-83  278.6  20.3    6.6e-83  278.6  20.3    2.7  2  Slu7       Pre-mRNA splicing Prp18-interacting factor
  ------ inclusion threshold ------
      0.017   14.9   0.4      0.071   12.9   0.6    2.0  2  zf-CCHC_4  Zinc knuckle


Domain annotation for each model (and alignments):
>> Slu7  Pre-mRNA splicing Prp18-interacting factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  278.6  20.3   7.3e-87   6.6e-83       1     269 []     111     350 ..     111     350 .. 0.92
   2 ?   -1.0   2.1      0.13   1.2e+03     197     232 ..     378     410 ..     362     447 .. 0.47

  Alignments for each domain:
  == domain 1  score: 278.6 bits;  conditional E-value: 7.3e-87
        Slu7   1 ldydakRDrwngYdpeeykkvveeyekieeerkklkeeelkkkaaeekekakkkeeeaedsdsdedeeedkddededkyaeeadmagekldeksritvr 99 
                 l++dakRDrwngYd++ey++vveeye++e+++k +k+++  +                  +d     ++++ d++e++yaee+dm ++     +++ +r
  EEA19523.1 111 LGWDAKRDRWNGYDASEYRNVVEEYEELENLKKSAKKAKDGE------------------ND-----DDEEGDQEEARYAEESDMGRQ-----QSTATR 181
                 58*******************************999888771..................11.....1233456789**********5.....9***** PP

        Slu7 100 nLRiReDtAkYLlnldlnsakYDPKtRsmrdnplketskkekklfagdnfvrasgeakefaklqlfAweaeekGe.dvhlqAnPtkaellakefkekke 197
                 nLRiReDtAkYLlnldl+sakYDPKtRsm   +++  +++   l+a++nf+rasg+a+ef+++q++Awe++e+G+ ++hlqAnPt++e+l+k++++++e
  EEA19523.1 182 NLRIREDTAKYLLNLDLDSAKYDPKTRSMIGLGAQADQTS--ALVAEENFIRASGDAAEFERAQKYAWESQERGDkQIHLQANPTSGEILRKREQAESE 278
                 *******************************988854444..489*****************************9688********************* PP

        Slu7 198 klkeekkksilekYggeehlkakpkel.llaqteayveysesgrvikgkekakakSkYeeDvlinnHtsVwGS 269
                 +++e+++k++lekYggeeh+ka+p +  ++ ++e++vey+e+g  ikg+ k+++kSkY+eD+linnH+sVwGS
  EEA19523.1 279 AKREAQRKALLEKYGGEEHMKAAPLREaAVIENERFVEYDETGA-IKGAPKKAVKSKYPEDILINNHKSVWGS 350
                 ********************9887555388*************9.8**************************9 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.13
        Slu7 197 eklkeekkksilekYggeehlkakpkelllaqteay 232
                 +++++++k +il++ + ee   ++p+e  ++q+e+ 
  EEA19523.1 378 RAFENTQKLAILDTLNHEE---EEPEEEPIKQEEEA 410
                 4444444444444444444...12222222222221 PP

>> zf-CCHC_4  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.6   7.9e-06     0.071      33      48 ..      70      85 ..      68      86 .. 0.91
   2 ?   -2.9   0.0      0.68   6.1e+03       2      20 ..     218     236 ..     218     238 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 7.9e-06
   zf-CCHC_4 33 fCyiCgvlGHsdkrCd 48
                +C++Cg ++H+ k+C 
  EEA19523.1 70 ACENCGAMTHKTKECL 85
                7**************7 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.68
   zf-CCHC_4   2 DvtkpLrafmkikkesGee 20 
                 D t +L+a+ ++  +sG+ 
  EEA19523.1 218 DQTSALVAEENFIRASGDA 236
                 67999***99999999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (460 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1338  (0.0746277); expected 358.6 (0.02)
Passed bias filter:                      454  (0.0253221); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.74u 0.35s 00:00:01.08 Elapsed: 00:00:00.56
# Mc/sec: 2481.09
//
Query:       EEA19524.1  [L=1655]
Description: DNA polymerase zeta catalytic subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   8.4e-100  334.6   0.0    1.2e-99  334.2   0.0    1.2  1  DNA_pol_B       DNA polymerase family B
    1.6e-21   76.8   0.0    2.4e-11   43.4   0.0    2.6  2  DNA_pol_B_exo1  DNA polymerase family B, exonuclease domain
    2.4e-18   66.4   5.7    2.4e-18   66.4   5.7    1.9  2  zf-C4pol        C4-type zinc-finger of DNA polymerase delta
  ------ inclusion threshold ------
       0.11   13.0   0.2       0.35   11.5   0.2    1.8  1  Cript           Microtubule-associated protein CRIPT
       0.41   10.6   2.5       0.92    9.5   2.5    1.7  1  PHD             PHD-finger


Domain annotation for each model (and alignments):
>> DNA_pol_B  DNA polymerase family B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  334.2   0.0  3.2e-103   1.2e-99       4     457 ..    1054    1499 ..    1051    1501 .. 0.90

  Alignments for each domain:
  == domain 1  score: 334.2 bits;  conditional E-value: 3.2e-103
                  HHHHHS-HHHHHHHHHHHHHHHTTBE-B-----.--SS.-S---.....-BE----EEESS-EEEEEETTHHHHHHHHTT-STTTCE-HCCHCCT-- CS
   DNA_pol_B    4 srvledgqqirveslLlrlakeegfilpdrtekkgkeeegYqGa.....tVlePkkglydkpvlvlDFaSLYPsiiqahNlcyttlvaseeeakele 95  
                   +v+++g+q++vesl++r+ak e+fil+ +++ k+  +   q a     +V+eP++ +y +p+lvlDF+SLYPsii+a+N+cy+t++ + ++ +   
  EEA19524.1 1054 FSVFSRGSQFKVESLMFRIAKPENFILI-SPSRKQVGQ---QNAleclpLVMEPQSDFYTSPLLVLDFQSLYPSIIIAYNYCYSTFLGRLDNWRGRG 1146
                  57899***********************.666645444...555555679*****************************************999444 PP

                  BTT................TEEE-TCC-EEE-TTS---HHHHHHHHHHHHHHHHHHHHHCS--.HHHHHHHHHHHHHHHHHHHHHHHHHTST.TSTT CS
   DNA_pol_B   96 aed.............eyleveveprlvefvkksvregllpklLkdllakRkaikkelkeekd.efekalldkqQlalKvtaNsvYGftGva.nsrl 177 
                  +                + +v+++p++  ++k++ r++ll+++L ++l+ R ++k+ +k++kd ++ ++ll+ +QlalK++aN +YG+t+++ ++r+
  EEA19524.1 1147 KMGfteykrqerilelLKDHVNIAPNGMIYAKPEIRKSLLARMLSEILETRVMVKSGMKADKDdKTLQQLLNHRQLALKMIANVTYGYTSASfSGRM 1243
                  33357788999999999999***************************************665505699************************99*** PP

                  --HHHHHHHHHHHHHHHHHHHHHHHHT...SSGGGT-SS......T-EEEEEBSSEEEEE-S-SSHHHHHHHHHHHHHHHHT.TSTTT--EEEEEEE CS
   DNA_pol_B  178 pclalAasvTtiGRemLektkelvekkaellskllalpeeaeee.klkviYGDTDSvfielkvkdveellkigkelaeevseklfkkplklefekvy 273 
                  pc ++A+s++++ Re+Le++ +++++                ++ +++v+YGDTDS+fi+lk+++ +e+++ig+e+ + v++ + + p+kl+fekvy
  EEA19524.1 1244 PCSEIADSIVQTARETLERAIAFIHSV---------------DRwGAEVVYGDTDSLFISLKGRTRDEAFTIGEEISKAVTK-MNPRPVKLKFEKVY 1324
                  *************************77...............2349************************************.999*********** PP

                  EEEEEEETTEEEEEEEEESSTTSE.EEEESSGGGSTTS-HHHHHHHHHHHHHHSSS....S-HHHHHHHHHHHHHHHHHHHHTT-S-GGGG-EEEEE CS
   DNA_pol_B  274 kkllLisKKkYaglkvektskank.lliKGvdlvRrdncklvkevikkvlelllkdeteersleeglealksilkdvleeleenkvplekfvlskel 369 
                  ++ +L++KK+Y+g+k+e++++ +  +++KG+++vRrd ++  +++ +k l+ l+++     +l+ + ++++++      ++++++v++++f++++e+
  EEA19524.1 1325 HPCVLLAKKRYVGFKYEHRDQVEPdFDAKGIETVRRDGTPAEQKIEEKALKILFRT----ADLSRVKDYFQKQC----LKIMQGRVSVQDFCFAREV 1413
                  *********************9966*******************************....78877777777777....99***************** PP

                  SS.CCCSSGCCSHHHHHHHHHHHHC.SS---TTCEEEEEEBETSS.....SS-GGGTEEEHHHHHHCC.SEB-HHHHHH.TTHHHHHHHHT CS
   DNA_pol_B  370 skepenyksknlphlevakrlkkrn.eeapevgdrisYvivekkkevkkknllaseraedpeyvlekn.lpidieyYls.qllkevarlle 457 
                  +  + + + +  + + + ++ + ++ + +p++g+r++Yv+v  +      + +  +r++ p ++l++  l++d+eyY++ +l+++++r+++
  EEA19524.1 1414 RLGTYSENGTLPAGALISTKKMLEDpRLEPQYGERVPYVVVTGAP-----GARLIDRCVAPGVLLNNAhLELDAEYYITkNLIPPLERIFN 1499
                  **755555555555556666666665888**************98.....99999******77777544********************98 PP

>> DNA_pol_B_exo1  DNA polymerase family B, exonuclease domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.7   0.0   4.9e-11   1.8e-07       2     125 ..      49     192 ..      48     253 .. 0.86
   2 !   43.4   0.0   6.6e-15   2.4e-11     157     337 .]     827     986 ..     789     986 .. 0.75

  Alignments for each domain:
  == domain 1  score: 30.7 bits;  conditional E-value: 4.9e-11
                     ECTTSEEEEEEEE---EEEEEESSCGGHHHHHHHHHHHCCTTCCCEE.............EEEEEECCCCEECCTSSCCHHC.EEEEEESSTCHH CS
  DNA_pol_B_exo1   2 teegksvcvnvfgfkpyfYceapdgkeleevkeelkelyeelskkvt.............kivkvelvlkkslygyekkpvp.ylkvsvsnpnel 82 
                     te g++vc +v+g  py+Y+e++ g  ++ev + ++ l+ +++  ++              + ++ lv+   +ygy+    + ylk+++ np ++
      EEA19524.1  49 TETGQKVCAHVHGAFPYLYIEYRGGLGQDEVNNAIRNLHASIDHALAnsyrqnaydgrvaYVAHISLVKGVPFYGYHVG-YRfYLKIYLLNPMNI 142
                     8999**************************************999999999********9999****************.567************ PP

                     HHHHHHHHH...CCCCCCCCSSS--HHHHHHHHCTS-TTCEEEEE....T CS
  DNA_pol_B_exo1  83 kkirkelsp...leeivdvyeydvdylerflidnkivgfgwysvk....k 125
                      ++ + l++    +++ + ye+  +++ + + d ++ g++++++     +
      EEA19524.1 143 IRLADLLRQgavMKTMLQPYESHLQFIPQWMCDYNLYGCAYMDCAkvkfR 192
                     *******999998899**************************99855551 PP

  == domain 2  score: 43.4 bits;  conditional E-value: 6.6e-15
                     S-EEEEEEEEEETEETTSEETTTT..--EEEEEEEECCTC.SS.SEEEEEEECCCTSS----EE--SSTCSTTEEEEEESSHHHHHHHHHHHHHH CS
  DNA_pol_B_exo1 157 pplrvlsFDIeckskkgkfpdaensedpiiqIscvldglgekepearklftlrecaseeeedfeltpkpeypgvkvlefdsEkelLqaflefikq 251
                       + v+s   ++  ++g  p++e+ +++ ++  ++++  +       +l+++                     v++ +++sE +l++  ++++++
      EEA19524.1 827 QYMSVMSLEVHVNTREGLAPNPEE-DEISVHLGILAQPAD-------VLVPVAAS----------------LSVEIQTEASELDLITSLVDIVRN 897
                     556667777777777776777776.444456666666655.......44444333................3469******************** PP

                     H--SEEEESSTTTTHHHHHHHHHHHCCTCCH.CG.SCCS..CTCEECCCCESEEEEEECEEEETTSEEEEHHHHHHHHSSSSG-SHHHH CS
  DNA_pol_B_exo1 252 ydPdvitgYNidnFDlpYilnRakelykvkl.sklgrln..kggrskvseigfskqarekvkisgrihlDlyrvvkrklklpsYkLnav 337
                     +dPd+itgY ++n  + Y+ +Ra+  y+++l   l+r++   +gr+  ++   ++++++++++ gr ++ + r ++ +l+l  Y+ ++v
      EEA19524.1 898 HDPDIITGYEVHNGSWGYLIERARVKYEYDLcNELSRVKasAHGRFGKDSDRWGFNNTSSISVTGRHMINIWRAMRSELNLLGYTMENV 986
                     ************************77776652456666677666655444444466************************999998876 PP

>> zf-C4pol  C4-type zinc-finger of DNA polymerase delta
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.1       2.2     8e+03      22      59 ..    1371    1408 ..    1366    1412 .. 0.77
   2 !   66.4   5.7   6.6e-22   2.4e-18       1      70 []    1551    1625 ..    1551    1625 .. 0.96

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 2.2
    zf-C4pol   22 esllkllsrlkelekklneletvCqsCaqgsleeevkC 59  
                  e++lk+l r+++l +  +  +++C +++qg ++ +  C
  EEA19524.1 1371 EKALKILFRTADLSRVKDYFQKQCLKIMQGRVSVQDFC 1408
                  44788888899999999999999*99988888766666 PP

  == domain 2  score: 66.4 bits;  conditional E-value: 6.6e-22
    zf-C4pol    1 ClvCkeklk.....kalCkkCrsdkqesllkllsrlkelekklneletvCqsCaqgsleeevkCdsrdCpvfYeR 70  
                  Cl+Ck+kl+      +lC++C+s ++ sl+kl s+l+++e++ ++l+++C+sC+++ + +ev+Cds+dCpvfY+R
  EEA19524.1 1551 CLICKDKLQdnnndLPLCNSCASLPHISLFKLTSQLQQAERRTSNLHKICRSCMGVPFGDEVSCDSKDCPVFYSR 1625
                  *****888888889***************************************999999**************98 PP

>> Cript  Microtubule-associated protein CRIPT
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.2   9.8e-05      0.35      26      66 ..    1532    1572 ..    1524    1577 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 9.8e-05
       Cript   26 genkllskkkrfnpyaaysskCkiCktkveqkgak..YCqkCa 66  
                  ++n ++skk  ++ y + ss C iCk k++ +++    C++Ca
  EEA19524.1 1532 NNNAAISKK-TLESYMK-SSTCLICKDKLQDNNNDlpLCNSCA 1572
                  567788888.5999998.89*********98766433799998 PP

>> PHD  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   2.5   0.00026      0.92       2      50 ..    1551    1604 ..    1550    1606 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00026
                  BTTTTS.TTSTTSCEEEETTTSCEEETTTSSSTHSHHSHHSS....TBSSTTTH CS
         PHD    2 CavCkk.ksdeeeelvqCdgCkrwfHqkClkppleseekpeg....ewlCekCk 50  
                  C +Ck+  +d++++l +C++C +  H +  k++ + ++ + +    + +C++C+
  EEA19524.1 1551 CLICKDkLQDNNNDLPLCNSCASLPHISLFKLTSQLQQAERRtsnlHKICRSCM 1604
                  ******87889****************999998776666555778878898885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1655 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       717  (0.0399911); expected 358.6 (0.02)
Passed bias filter:                      570  (0.0317921); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 1.08u 0.34s 00:00:01.42 Elapsed: 00:00:00.54
# Mc/sec: 9281.37
//
Query:       EEA19525.1  [L=574]
Description: MFS sugar transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     1e-120  403.7  16.0   1.6e-120  403.0  16.0    1.3  1  Sugar_tr  Sugar (and other) transporter
    1.7e-24   86.5  42.0    3.2e-14   52.6  17.3    2.6  2  MFS_1     Major Facilitator Superfamily
     0.0007   18.1   1.2     0.0007   18.1   1.2    2.4  3  TRI12     Fungal trichothecene efflux pump (TRI12)
  ------ inclusion threshold ------
        7.1    7.0   9.2        0.6   10.4   0.1    3.1  3  DUF3382   Domain of unknown function (DUF3382)


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  403.0  16.0  3.6e-124  1.6e-120       1     452 []      30     530 ..      30     530 .. 0.95

  Alignments for each domain:
  == domain 1  score: 403.0 bits;  conditional E-value: 3.6e-124
                 HHHHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTT CS
    Sugar_tr   1 valvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgk 99 
                 val+ +lggllfgYd gvi+++lt+++f  +f    ++s+ e      g++vs +l+ a +Gsl  g++gdr+GRk s+lia+v+f +g+++q  a+  
  EEA19525.1  30 VALFSTLGGLLFGYDQGVISGILTMQSFGARFPRIYTDSNFE------GWFVSTLLLAAWFGSLCNGPIGDRLGRKASMLIAVVIFTVGSAIQCSAQ-- 120
                 578889**********************99999888887777......8************************************************.. PP

                 SS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-................................ CS
    Sugar_tr 100 nsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsn................................ 166
                  ++ +l++gR ++G+++G  + +vP++isEi+ +++Rg lv+l+ql+it+Gil+++++++g+n++++                                
  EEA19525.1 121 -NIPMLFAGRAVAGFAIGQLTQIVPLFISEISVPEIRGSLVVLQQLSITIGILISFWIDYGTNYIGGircapsipytggtpskrtfnpyidipadgrct 218
                 .************************************************************************************************** PP

                 ...TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHHTT-HHHHHHHHHH.HHHCHHHHHHHHHHHHHHHHHHH...................HTTHHH CS
    Sugar_tr 167 ...adgwrillglqlvpallllilllflPESPrylvekgkeeeakevlak.lrgeedadrelaeekdsleaeqeee..............kaswkells 247
                    +  wr+++++q+vp+l l ++++f+P+SPr+l++++++e+a ++l k  r++e +d+++++e+ +++a+   e                 + +++s
  EEA19525.1 219 gqsEASWRLPFAFQIVPTLSLGVGMFFFPDSPRWLLMRERDEDAIATLCKlRRKTERDDPDIVKEYLEIKASIMLEnsfakdkwpelsgiRLEVAQYVS 317
                 ***99*********************************************6666799999********9999887789999999999999777777777 PP

                 HSH......HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH...HHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH...HH CS
    Sugar_tr 248 skt...vrqrlligvvlqifqqltGinaimyysptifenlglsks...llvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilg.ival 339
                  +t    ++rl ig+v+++fqq+ G+na++yy+ptif +lgls     ll+t+++g++n ++t+ a+f++d++GRR+ll+ Ga+g ++ +vi++ i+  
  EEA19525.1 318 LVTswpRFKRLAIGCVVMFFQQFMGCNAMIYYAPTIFAQLGLSGNttsLLATGVYGIINCLSTLPALFFIDKVGRRPLLMCGAIGTCVSLVIVAgIIGV 416
                 7777779************************************99999*********************************************974444 PP

                 HHTTSS.....CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHH CS
    Sugar_tr 340 llvaks..kaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfff 436
                  ++a    k+a+ + i+fi+++ + f+ +++pv wvl sE+f +s+Rska++i++ + w++nf+i+l++p ++++i+ ++++l+fa+++++++ f+ff 
  EEA19525.1 417 YGSALVdhKSAGWAGIAFIYIYDVNFSYSFAPVGWVLPSEIFNLSIRSKAISITTSATWMCNFIIGLVTPDMLSSIT-WGTYLFFAVFCLIAFAFTFFV 514
                 444433679********************************************************************.********************* PP

                 S--STT--CCCCGGGT CS
    Sugar_tr 437 vpetkgrtleeieelf 452
                 +pet g+tle+++ +f
  EEA19525.1 515 IPETRGKTLEDMDLIF 530
                 ***********99766 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.6  17.3   7.2e-18   3.2e-14       3     233 ..      36     353 ..      27     356 .. 0.84
   2 !   42.4  20.2   9.1e-15   4.1e-11       3     187 ..     334     528 ..     328     560 .. 0.76

  Alignments for each domain:
  == domain 1  score: 52.6 bits;  conditional E-value: 7.2e-18
       MFS_1   3 laaflsalarsilgpalplalaedlg.......ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfasslwlllvlrv 93 
                 l+++l +++ ++++ +l+   ++++g        +  + g+ +++  l+a+++sl  G+++dr+Gr+  +l+++++f +g ++ ++ a+++++l+++r+
  EEA19525.1  36 LGGLLFGYDQGVISGILT---MQSFGarfpriyTDSNFEGWFVSTLLLAAWFGSLCNGPIGDRLGRKASMLIAVVIFTVGsAIQCS-AQNIPMLFAGRA 130
                 678888999999999998...688888888888788889*****************************************555555.59999******* PP

       MFS_1  94 lqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg......................................Wravf 154
                 ++G++ g l+ ++  +i++++ +e rg+ + l ++++ +G+++   +       +g                                      Wr++f
  EEA19525.1 131 VAGFAIGQLTQIVPLFISEISVPEIRGSLVVLQQLSITIGILISFWIDYGTNYIGGircapsipytggtpskrtfnpyidipadgrctgqseasWRLPF 229
                 ****************************************************7777******************************************* PP

       MFS_1 155 yilaivsllafvlfllllpeepperkrkspkeee............................................kgtgpaplvpawkallkdpvl 209
                  +  + +l ++v +++++p++p+     +    e                                             +  + ++++ + +l+++ + 
  EEA19525.1 230 AFQIVPTLSLGV-GMFFFPDSPRWLLMRERD--EdaiatlcklrrkterddpdivkeyleikasimlensfakdkwpeLSGIRLEVAQ-YVSLVTSWPR 324
                 ************.336665555554444444..4459999999999999999999999999999999988877655554444444444.4444444433 PP

       MFS_1 210 w.....illialllfffgfsglltllply 233
                 +      ++++++  f+g +++ ++ p++
  EEA19525.1 325 FkrlaiGCVVMFFQQFMGCNAMIYYAPTI 353
                 254455688888888888888******96 PP

  == domain 2  score: 42.4 bits;  conditional E-value: 9.1e-15
       MFS_1   3 laaflsalarsilgpalplalaedlgispseigllltl.yalgaavaslplGrlsdrfGrrrvlllglllfalglllll.f......a......sslwl 87 
                 +++f  +++ ++ +  +p ++  +lg+s+ + +ll+t+ y++  ++++lp+ +++d++Grr++l++g+++++++l++ + +      a      ++ w+
  EEA19525.1 334 VMFFQQFMGCNAMIYYAP-TIFAQLGLSGNTTSLLATGvYGIINCLSTLPALFFIDKVGRRPLLMCGAIGTCVSLVIVAgIigvygsAlvdhksAG-WA 430
                 344555555555556666.99*************88888***********************************5555564354454166766344.44 PP

       MFS_1  88 llvlrvlqGl.gagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspk 185
                  +++  +  + ++ +++p+g +l +++f+ + r++ai++ ++++ +   +  l+ + ++ss+ W ++++++a+++l+af +   +++ ++++ k+ ++ 
  EEA19525.1 431 GIAFIYIYDVnFSYSFAPVGWVLPSEIFNLSIRSKAISITTSATWMCNFIIGLVTPDMLSSITW-GTYLFFAVFCLIAFAF--TFFVIPETRGKTLEDM 526
                 444444555414578999999********************98888885555666656668899.8************776..8888888877776665 PP

       MFS_1 186 ee 187
                 ++
  EEA19525.1 527 DL 528
                 55 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   1.2   1.6e-07    0.0007      53     160 ..      47     152 ..      39     176 .. 0.77
   2 ?    1.9   0.7     0.013        60      66     122 ..     349     407 ..     323     441 .. 0.69
   3 ?    0.2   1.7     0.041   1.8e+02     308     393 ..     388     479 ..     353     536 .. 0.65

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 1.6e-07
       TRI12  53 vvatyfvlqasasalpnilqdvgqsensslfstlwttgqavsilvmgrltdrfgrrpfvilthilglvgaivgctatkfntllaamtllgvaagpag.a 150
                 v++  + +q+  + +p i  d   s+ ++ f +   +      l  g + dr+gr+  ++++ ++  vg+ + c+a+++  l+a  ++ g a g     
  EEA19525.1  47 VISGILTMQSFGARFPRIYTD---SNFEGWFVSTLLLAAWFGSLCNGPIGDRLGRKASMLIAVVIFTVGSAIQCSAQNIPMLFAGRAVAGFAIGQLTqI 142
                 555556666666666666665...5556666444445556667899************************************************86516 PP

       TRI12 151 splfvgelms 160
                  plf+ e+  
  EEA19525.1 143 VPLFISEISV 152
                 8*****9865 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.013
       TRI12  66 alpnilqdvgqsens.slfst.lwttgqavsilvmgrltdrfgrrpfvilthilglvga 122
                   p i+ ++g s n+ sl++t ++ + +++s l    + d++grrp+++   i   v  
  EEA19525.1 349 YAPTIFAQLGLSGNTtSLLATgVYGIINCLSTLPALFFIDKVGRRPLLMCGAIGTCVSL 407
                 45888888888877525555437788888888888888899999998877665443332 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.041
       TRI12 308 dtrgfvcillissimgamnlslviiypqqvvnifgsslknweetawmsat......asfg...tgagvvvlgslfhl.vrhirwqilvgalwltaf 393
                 d  g   +l+     ga+  ++ ++    ++ ++gs+l + + + w   +        f    +  g v+  ++f l +r     i   a w+  f
  EEA19525.1 388 DKVGRRPLLMC----GAIGTCVSLVIVAGIIGVYGSALVDHKSAGWAGIAfiyiydVNFSysfAPVGWVLPSEIFNLsIRSKAISITTSATWMCNF 479
                 44444444433....455555555556678888888888777777754331111111221101223445555666654566666666666666666 PP

>> DUF3382  Domain of unknown function (DUF3382)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.1   0.00013       0.6      29      54 ..     307     341 ..     304     345 .. 0.75
   2 ?   -3.4   0.4       2.8   1.3e+04       9      23 ..     402     416 ..     399     435 .. 0.67
   3 ?    0.9   0.5      0.13   5.7e+02      17      55 ..     477     514 ..     465     523 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00013
     DUF3382  29 gtrlvlep.........rwglvaiavavvfvgqLl 54 
                 g+rl++ +         r++++ai+++v+f+ q++
  EEA19525.1 307 GIRLEVAQyvslvtswpRFKRLAIGCVVMFFQQFM 341
                 55555555555555566**************9985 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 2.8
     DUF3382   9 aallalvlfvpilGl 23 
                  + + lv+++ i+G+
  EEA19525.1 402 GTCVSLVIVAGIIGV 416
                 566788888888887 PP

  == domain 3  score: 0.9 bits;  conditional E-value: 0.13
     DUF3382  17 fvpilGlqleldgtrlvleprwglvaiavavvfvgqLlr 55 
                 + +i+Gl  + d  + + ++++   a+++++ f++ +++
  EEA19525.1 477 CNFIIGL-VTPDMLSSITWGTYLFFAVFCLIAFAFTFFV 514
                 5677777.3344445555667888999********9985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (574 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       563  (0.0314016); expected 358.6 (0.02)
Passed bias filter:                      276  (0.0153941); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.64u 0.28s 00:00:00.92 Elapsed: 00:00:00.47
# Mc/sec: 3641.81
//
Query:       EEA19526.1  [L=532]
Description: MFS sugar transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.9e-117  392.9  17.5   3.4e-117  392.1  17.5    1.3  1  Sugar_tr  Sugar (and other) transporter
    1.6e-22   79.9  47.1    2.8e-14   52.8  17.3    2.6  2  MFS_1     Major Facilitator Superfamily
    0.00062   18.3   1.2    0.00062   18.3   1.2    2.4  3  TRI12     Fungal trichothecene efflux pump (TRI12)
  ------ inclusion threshold ------
       0.55   10.5   0.1       0.55   10.5   0.1    3.2  3  DUF3382   Domain of unknown function (DUF3382)


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  392.1  17.5  7.5e-121  3.4e-117       1     443 [.      30     521 ..      30     524 .. 0.95

  Alignments for each domain:
  == domain 1  score: 392.1 bits;  conditional E-value: 7.5e-121
                 HHHHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTT CS
    Sugar_tr   1 valvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgk 99 
                 val+ +lggllfgYd gvi+++lt+++f  +f    ++s+ e      g++vs +l+ a +Gsl  g++gdr+GRk s+lia+v+f +g+++q  a+  
  EEA19526.1  30 VALFSTLGGLLFGYDQGVISGILTMQSFGARFPRIYTDSNFE------GWFVSTLLLAAWFGSLCNGPIGDRLGRKASMLIAVVIFTVGSAIQCSAQ-- 120
                 578889**********************99999888887777......8************************************************.. PP

                 SS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-................................ CS
    Sugar_tr 100 nsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsn................................ 166
                  ++ +l++gR ++G+++G  + +vP++isEi+ +++Rg lv+l+ql+it+Gil+++++++g+n++++                                
  EEA19526.1 121 -NIPMLFAGRAVAGFAIGQLTQIVPLFISEISVPEIRGSLVVLQQLSITIGILISFWIDYGTNYIGGircapsipytggtpskrtfnpyidipadgrct 218
                 .************************************************************************************************** PP

                 ...TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHHTT-HHHHHHHHHH.HHHCHHHHHHHHHHHHHHHHHHH...................HTTHHH CS
    Sugar_tr 167 ...adgwrillglqlvpallllilllflPESPrylvekgkeeeakevlak.lrgeedadrelaeekdsleaeqeee..............kaswkells 247
                    +  wr+++++q+vp+l l ++++f+P+SPr+l++++++e+a ++l k  r++e +d+++++e+ +++a+   e                 + +++s
  EEA19526.1 219 gqsEASWRLPFAFQIVPTLSLGVGMFFFPDSPRWLLMRERDEDAIATLCKlRRKTERDDPDIVKEYLEIKASIMLEnsfakdkwpelsgiRLEVAQYVS 317
                 ***99*********************************************6666799999********9999887789999999999999777777777 PP

                 HSH......HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH...HHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH...HH CS
    Sugar_tr 248 skt...vrqrlligvvlqifqqltGinaimyysptifenlglsks...llvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilg.ival 339
                  +t    ++rl ig+v+++fqq+ G+na++yy+ptif +lgls     ll+t+++g++n ++t+ a+f++d++GRR+ll+ Ga+g ++ +vi++ i+  
  EEA19526.1 318 LVTswpRFKRLAIGCVVMFFQQFMGCNAMIYYAPTIFAQLGLSGNttsLLATGVYGIINCLSTLPALFFIDKVGRRPLLMCGAIGTCVSLVIVAgIIGV 416
                 7777779************************************99999*********************************************974444 PP

                 HHTTSS.....CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHH CS
    Sugar_tr 340 llvaks..kaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfff 436
                  ++a    k+a+ + i+fi+++ + f+ +++pv wvl sE+f +s+Rska++i++ + w++nf+i+l++p ++++i+ ++++l+fa+++++++ f+ff 
  EEA19526.1 417 YGSALVdhKSAGWAGIAFIYIYDVNFSYSFAPVGWVLPSEIFNLSIRSKAISITTSATWMCNFIIGLVTPDMLSSIT-WGTYLFFAVFCLIAFAFTFFV 514
                 444433679********************************************************************.********************* PP

                 S--STT- CS
    Sugar_tr 437 vpetkgr 443
                 +pet g+
  EEA19526.1 515 IPETRGK 521
                 ****997 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.8  17.3   6.2e-18   2.8e-14       3     233 ..      36     353 ..      34     356 .. 0.84
   2 !   35.6  25.3     1e-12   4.6e-09       3     178 ..     334     519 ..     328     526 .. 0.76

  Alignments for each domain:
  == domain 1  score: 52.8 bits;  conditional E-value: 6.2e-18
       MFS_1   3 laaflsalarsilgpalplalaedlg.......ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfasslwlllvlrv 93 
                 l+++l +++ ++++ +l+   ++++g        +  + g+ +++  l+a+++sl  G+++dr+Gr+  +l+++++f +g ++ ++ a+++++l+++r+
  EEA19526.1  36 LGGLLFGYDQGVISGILT---MQSFGarfpriyTDSNFEGWFVSTLLLAAWFGSLCNGPIGDRLGRKASMLIAVVIFTVGsAIQCS-AQNIPMLFAGRA 130
                 678889999999999998...688888888888788889*****************************************555555.59999******* PP

       MFS_1  94 lqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg......................................Wravf 154
                 ++G++ g l+ ++  +i++++ +e rg+ + l ++++ +G+++   +       +g                                      Wr++f
  EEA19526.1 131 VAGFAIGQLTQIVPLFISEISVPEIRGSLVVLQQLSITIGILISFWIDYGTNYIGGircapsipytggtpskrtfnpyidipadgrctgqseasWRLPF 229
                 ****************************************************7777******************************************* PP

       MFS_1 155 yilaivsllafvlfllllpeepperkrkspkeee............................................kgtgpaplvpawkallkdpvl 209
                  +  + +l ++v +++++p++p+     +    e                                             +  + ++++ + +l+++ + 
  EEA19526.1 230 AFQIVPTLSLGV-GMFFFPDSPRWLLMRERD--EdaiatlcklrrkterddpdivkeyleikasimlensfakdkwpeLSGIRLEVAQ-YVSLVTSWPR 324
                 ************.336665555554444444..4459999999999999999999999999999999988877655554444444444.4444444433 PP

       MFS_1 210 w.....illialllfffgfsglltllply 233
                 +      ++++++  f+g +++ ++ p++
  EEA19526.1 325 FkrlaiGCVVMFFQQFMGCNAMIYYAPTI 353
                 254455688888888888888******96 PP

  == domain 2  score: 35.6 bits;  conditional E-value: 1e-12
       MFS_1   3 laaflsalarsilgpalplalaedlgispseigllltl.yalgaavaslplGrlsdrfGrrrvlllglllfalglllll.f......a......sslwl 87 
                 +++f  +++ ++ +  +p ++  +lg+s+ + +ll+t+ y++  ++++lp+ +++d++Grr++l++g+++++++l++ + +      a      ++ w+
  EEA19526.1 334 VMFFQQFMGCNAMIYYAP-TIFAQLGLSGNTTSLLATGvYGIINCLSTLPALFFIDKVGRRPLLMCGAIGTCVSLVIVAgIigvygsAlvdhksAG-WA 430
                 344555555555556666.99*************88888***********************************5555564354454166766344.44 PP

       MFS_1  88 llvlrvlqGl.gagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeeppe 178
                  +++  +  + ++ +++p+g +l +++f+ + r++ai++ ++++ +   +  l+ + ++ss+ W ++++++a+++l+af +   +++ ++++
  EEA19526.1 431 GIAFIYIYDVnFSYSFAPVGWVLPSEIFNLSIRSKAISITTSATWMCNFIIGLVTPDMLSSITW-GTYLFFAVFCLIAFAF--TFFVIPETR 519
                 444444555414578999999********************98888885555666656668899.8************887..555555554 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   1.2   1.4e-07   0.00062      53     160 ..      47     152 ..      39     176 .. 0.77
   2 ?    1.9   0.7     0.013        57      66     122 ..     349     407 ..     323     439 .. 0.69
   3 ?   -0.1   1.8     0.054   2.4e+02     308     393 ..     388     479 ..     357     493 .. 0.60

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 1.4e-07
       TRI12  53 vvatyfvlqasasalpnilqdvgqsensslfstlwttgqavsilvmgrltdrfgrrpfvilthilglvgaivgctatkfntllaamtllgvaagpag.a 150
                 v++  + +q+  + +p i  d   s+ ++ f +   +      l  g + dr+gr+  ++++ ++  vg+ + c+a+++  l+a  ++ g a g     
  EEA19526.1  47 VISGILTMQSFGARFPRIYTD---SNFEGWFVSTLLLAAWFGSLCNGPIGDRLGRKASMLIAVVIFTVGSAIQCSAQNIPMLFAGRAVAGFAIGQLTqI 142
                 555556666666666766665...5556666444445556667899************************************************86516 PP

       TRI12 151 splfvgelms 160
                  plf+ e+  
  EEA19526.1 143 VPLFISEISV 152
                 8*****9865 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.013
       TRI12  66 alpnilqdvgqsens.slfst.lwttgqavsilvmgrltdrfgrrpfvilthilglvga 122
                   p i+ ++g s n+ sl++t ++ + +++s l    + d++grrp+++   i   v  
  EEA19526.1 349 YAPTIFAQLGLSGNTtSLLATgVYGIINCLSTLPALFFIDKVGRRPLLMCGAIGTCVSL 407
                 45888888888877525555437788888888888888999999998877665443332 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.054
       TRI12 308 dtrgfvcillissimgamnlslviiypqqvvnifgsslknweetawmsat......asfg...tgagvvvlgslfhl.vrhirwqilvgalwltaf 393
                 d  g   +l+     ga+  ++ ++    ++ ++gs+l + + + w   +        f    +  g v+  ++f l +r     i   a w+  f
  EEA19526.1 388 DKVGRRPLLMC----GAIGTCVSLVIVAGIIGVYGSALVDHKSAGWAGIAfiyiydVNFSysfAPVGWVLPSEIFNLsIRSKAISITTSATWMCNF 479
                 44444444443....555556666666789999999998888888865431111111222101223555556666664566666666666666666 PP

>> DUF3382  Domain of unknown function (DUF3382)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.1   0.00012      0.55      29      54 ..     307     341 ..     304     345 .. 0.75
   2 ?   -3.2   0.3       2.3     1e+04       9      23 ..     402     416 ..     399     436 .. 0.66
   3 ?    0.6   0.8      0.15   6.9e+02      17      55 ..     477     514 ..     465     518 .. 0.73

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00012
     DUF3382  29 gtrlvlep.........rwglvaiavavvfvgqLl 54 
                 g+rl++ +         r++++ai+++v+f+ q++
  EEA19526.1 307 GIRLEVAQyvslvtswpRFKRLAIGCVVMFFQQFM 341
                 55555555555555567**************9985 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.3
     DUF3382   9 aallalvlfvpilGl 23 
                  + + lv+++ i+G+
  EEA19526.1 402 GTCVSLVIVAGIIGV 416
                 566788888888887 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.15
     DUF3382  17 fvpilGlqleldgtrlvleprwglvaiavavvfvgqLlr 55 
                 + +i+Gl  + d  + + ++++   a+++++ f++ +++
  EEA19526.1 477 CNFIIGL-VTPDMLSSITWGTYLFFAVFCLIAFAFTFFV 514
                 5677777.3344445555667888999*******99985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (532 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       750  (0.0418317); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.46
# Mc/sec: 3498.80
//
Query:       EEA19527.1  [L=675]
Description: C6 transcription factor (Gal4), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.8e-26   91.4   1.6    5.2e-26   91.3   0.5    1.6  2  Fungal_trans  Fungal specific transcription factor domain
    5.5e-10   39.2   9.8    9.8e-10   38.4   9.8    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
    7.3e-06   26.1   0.0    1.4e-05   25.1   0.0    1.5  1  Gal4_dimer    Gal4-like dimerisation domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.3   0.5   8.7e-30   5.2e-26       1     181 [.     212     376 ..     212     454 .. 0.88
   2 ?   -2.8   0.0      0.42   2.5e+03     161     176 ..     534     549 ..     497     559 .. 0.70

  Alignments for each domain:
  == domain 1  score: 91.3 bits;  conditional E-value: 8.7e-30
  Fungal_trans   1 ldrffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsL 97 
                   +d++f n+h+ +p++h+ +f  +++ + +++     ++ll++ilalGa + +++++  +          i+f+++a++++ +  + +  +++ +q+L
    EEA19527.1 212 IDSYFMNYHSSYPFVHESTFRAQYHEQIPRPHGPVWHILLNTILALGAWCIGDDSSDLD----------ITFYQEARSYLQQTSVFEMGNITLVQAL 298
                   79**********************9999999999999******************9973..........667777787777777778888******* PP

  Fungal_trans  98 lllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqi 181
                   +ll+ y + + + +  ++++g+avr++ slg h++ + ++       +  ++e+rrRlww++F++D   a  +Grp ll+d+ i
    EEA19527.1 299 VLLSNYTQKRNKPNTGWNYLGLAVRMSMSLGIHKEFPGWK------ISLLQREIRRRLWWGVFMFDSGAAKTFGRPILLPDETI 376
                   **************************************99......*******************************8787765 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.42
  Fungal_trans 161 ylDktialklGrppll 176
                   y++++ ++ lG +++l
    EEA19527.1 534 YMETHMCTRLGAWYIL 549
                   6666666666666643 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.4   9.8   1.6e-13   9.8e-10       2      37 ..      11      45 ..      10      48 .. 0.92

  Alignments for each domain:
  == domain 1  score: 38.4 bits;  conditional E-value: 1.6e-13
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfysess 37
                aCd+Cr +K++C+++kP+C +C kl++eC  ys + 
  EEA19527.1 11 ACDECRARKSRCSKGKPKCLQCLKLGKECI-YSPKI 45
                9*****************************.88765 PP

>> Gal4_dimer  Gal4-like dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1   0.0   2.4e-09   1.4e-05       1      32 [.      51      82 ..      51     107 .. 0.86

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 2.4e-09
  Gal4_dimer  1 TRAhLTeVEsRvtqLEqlLrrllpeeDiDnlL 32
                TR hLT VE R++  E  L +l+p  D+Dn++
  EEA19527.1 51 TRQHLTYVEDRLNAVETALSKLFPGGDLDNVV 82
                9****************************964 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (675 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       720  (0.0401584); expected 358.6 (0.02)
Passed bias filter:                      536  (0.0298957); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.71u 0.29s 00:00:01.00 Elapsed: 00:00:00.48
# Mc/sec: 4186.60
//
Query:       EEA19528.1  [L=227]
Description: ThiJ/PfpI family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.5e-16   59.9   0.0      3e-16   59.6   0.0    1.1  1  DJ-1_PfpI  DJ-1/PfpI family


Domain annotation for each model (and alignments):
>> DJ-1_PfpI  DJ-1/PfpI family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.6   0.0   1.7e-20     3e-16      39     164 ..      73     198 ..      43     199 .. 0.88

  Alignments for each domain:
  == domain 1  score: 59.6 bits;  conditional E-value: 1.7e-20
                 EEEETTSEEEE-SEEGGGCTCCG-SEEEE--BHHHHHHHHTSHHHHHHHHHHHHTT-EEEEETTTHHHHHHTTTTTTSEE--SGGGHHHH..HHTTSEE CS
   DJ-1_PfpI  39 evkgsrGlkvtvdaslddvkaaeyDalvlpGGragperlrenekvvelvkefaekgklvaaICagpqlLaaagvlkgrrvTsypavkdkl..ekagaky 135
                 +v+++ G+ +t +   +dv++++ D+lv+pG +  p+++ + ek +e+v+ + e+++++  IC g+++ a+ g+  gr vT+  a+ + l  e + a++
  EEA19528.1  73 QVTSTAGVCLTHTIDDKDVSPGNLDILVIPGPE--PTTIPD-EKTQEFVRAHNENKTTFLVICSGAFVTARSGIYGGRHVTGPRAFLPVLkkEFPTATW 168
                 56777776666666667*************974..699997.6****************************************9999888545678999 PP

                 -SS.SEEEETTEEEESSGGGHHHHHHHHHH CS
   DJ-1_PfpI 136 vdk.rvvvdgnlvTsrgpgaaiefalelle 164
                  d+ rvv+dg l T+ g +  +++  ++l+
  EEA19528.1 169 DDSvRVVQDGHLWTAGGITNGMDLVAAYLK 198
                 999*********************999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (227 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       265  (0.0147805); expected 358.6 (0.02)
Passed bias filter:                      246  (0.0137208); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.27s 00:00:00.67 Elapsed: 00:00:00.42
# Mc/sec: 1625.14
//
Query:       EEA19529.1  [L=138]
Description: cytochrome c oxidase subunit VIa, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-51  173.9   1.8    1.4e-51  173.7   1.8    1.0  1  COX6A     Cytochrome c oxidase subunit VIa


Domain annotation for each model (and alignments):
>> COX6A  Cytochrome c oxidase subunit VIa
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  173.7   1.8   7.6e-56   1.4e-51       2     112 .]      25     135 ..      24     135 .. 0.98

  Alignments for each domain:
  == domain 1  score: 173.7 bits;  conditional E-value: 7.6e-56
       COX6A   2 qraqrrfasseakkaaaaeneFvkereavkeHaeettdlwrklslyvaipalilaainaynlekeHaeHvehlkeleerteYeYqnirtknffwGdGdk 100
                 + +qrrf+s+e+k     +n+F++ere+vk+Ha++t+ lw +ls+y++ip+li  +inaynl++eH+eH++h+++le+rteY+Yqnir+knf+wGdGdk
  EEA19529.1  25 NVVQRRFNSTETKPDWLVDNAFNRERENVKHHAASTSTLWLRLSIYAVIPCLIGGGINAYNLWNEHWEHWNHMPPLEDRTEYAYQNIRSKNFPWGDGDK 123
                 5689*********************************************************************************************** PP

       COX6A 101 tlFwNdkvNyhk 112
                 t+FwN++vNyh+
  EEA19529.1 124 TIFWNPEVNYHN 135
                 ***********7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (138 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       349  (0.0194657); expected 358.6 (0.02)
Passed bias filter:                      276  (0.0153941); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.30s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 912.09
//
Query:       EEA19530.1  [L=126]
Description: cytochrome c oxidase subunit VIa, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-44  150.0   0.1    3.6e-44  149.8   0.1    1.0  1  COX6A     Cytochrome c oxidase subunit VIa


Domain annotation for each model (and alignments):
>> COX6A  Cytochrome c oxidase subunit VIa
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  149.8   0.1     2e-48   3.6e-44       2     102 ..      25     125 ..      24     126 .] 0.98

  Alignments for each domain:
  == domain 1  score: 149.8 bits;  conditional E-value: 2e-48
       COX6A   2 qraqrrfasseakkaaaaeneFvkereavkeHaeettdlwrklslyvaipalilaainaynlekeHaeHvehlkeleerteYeYqnirtknffwGdGdk 100
                 + +qrrf+s+e+k     +n+F++ere+vk+Ha++t+ lw +ls+y++ip+li  +inaynl++eH+eH++h+++le+rteY+Yqnir+knf+wGdGdk
  EEA19530.1  25 NVVQRRFNSTETKPDWLVDNAFNRERENVKHHAASTSTLWLRLSIYAVIPCLIGGGINAYNLWNEHWEHWNHMPPLEDRTEYAYQNIRSKNFPWGDGDK 123
                 5689*********************************************************************************************** PP

       COX6A 101 tl 102
                 t+
  EEA19530.1 124 TI 125
                 *8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (126 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       472  (0.0263261); expected 358.6 (0.02)
Passed bias filter:                      385  (0.0214736); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.45
# Mc/sec: 845.16
//
Query:       EEA19531.1  [L=607]
Description: DNA lyase Apn2 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      7e-13   48.6   0.1    1.1e-12   47.9   0.1    1.3  1  Exo_endo_phos  Endonuclease/Exonuclease/phosphatase family
    9.1e-05   22.5   0.7    0.00022   21.3   0.7    1.7  1  zf-GRF         GRF zinc finger


Domain annotation for each model (and alignments):
>> Exo_endo_phos  Endonuclease/Exonuclease/phosphatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.9   0.1   1.3e-16   1.1e-12      25     233 .]      23     303 ..       8     303 .. 0.82

  Alignments for each domain:
  == domain 1  score: 47.9 bits;  conditional E-value: 1.3e-16
                    HHHHCTTSEEEEEEEBSCTCHHHHHHHHHTTCEEEEECCHECSSSTTSSEEEEEECSTEEEEEEEEEEETSSSSGCEEEEEEEEEEEEEEE..... CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..... RF
  Exo_endo_phos  25 lltaydaDvlgLQEvdddelsriplllalggflgasstsptgggggggnggavlsrfpltslfrrtfiefndlvaalrreplaakleqlni..... 115
                    +l    aD++ +QE++ +  ++++   +  g+++++s +   +  +g+ g++++ r  + + +r     ++ l  +  ++p      + +i     
     EEA19531.1  23 IL---EADIVIFQETKIQRKDLRDDMVLVPGWDCYFSLP---RHKKGYSGVVIYTRNEVCAPIRAEEGITGLLCPPSTTTPYRHLPDDQQIggyps 112
                    44...459******9999877776666665555555553...778**************8886666666666666666666666666666699999 PP

                    ....................................CCCHHGHHHHHHHHHHHHHHHHHHHHHTTSEEEEEEE-SSSTSGGGBSCGHHHHHHCTTT CS
                    ....................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Exo_endo_phos 116 ....................................ashrdhdlvrdlqllalllqvealnadrgapvivaGDfNarpsdddsrvlrtrglalapa 175
                                                        a +   ++  ++ ++ ll++++++  + g++viv+GD+N    + ds +l+++ +   + 
     EEA19531.1 113 meqlndlqidpavldcegrcvilefpafvlfglycpAARDETRDHFRQGFITLLDARIRNLVAMGKRVIVTGDLNISAGEIDSAHLTEAIRKGTGS 208
                    999999999*******************************************************************99999988888777777766 PP

                    H....................H........................SSCESCETTTTTTTTTTTEB-BEEEEEECHHHCCEEEEEEECCHHEECTS CS
                    x....................x........................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Exo_endo_phos 176 p....................v........................glyllgggptptyvtraggsrlDrilaspalalfrsgvlppplalvrrea 227
                                         v                         + +++++++ ++++ ++g r+D+il s + + + s+ ++ ++       
     EEA19531.1 209 EdefvsgpvrrvfnqlvegakVigkrdsgrevpvlhdicrsfhpdrRGMYTCWETRVNARPGNYGARIDYILSSLDIKDWWSEGNIQEG------- 297
                    688888887777776666655055666667777788889999********************************888888888887776....... PP

                    SCSSSB CS
                    xxxxxx RF
  Exo_endo_phos 228 ltlSDH 233
                    l++SDH
     EEA19531.1 298 LMGSDH 303
                    889999 PP

>> zf-GRF  GRF zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.7   2.4e-08   0.00022       2      31 ..     549     579 ..     548     602 .. 0.86

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 2.4e-08
      zf-GRF   2 lCk.cgrlavlltvrktgpNkGRkFYkCpkg 31 
                  C+ +++++ +lt +k g N GR F+ C+ +
  EEA19531.1 549 RCEdHQEPCIMLTTKKAGINCGRSFWMCSRP 579
                 699899**********************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (607 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       547  (0.0305092); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 3877.75
//
Query:       EEA19532.1  [L=328]
Description: mating type protein MAT1-2-1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    7.1e-21   74.4   0.3    1.3e-20   73.6   0.3    1.4  1  HMG_box    HMG (high mobility group) box
    7.4e-06   26.5   0.4    1.5e-05   25.5   0.4    1.6  1  HMG_box_2  HMG-box domain


Domain annotation for each model (and alignments):
>> HMG_box  HMG (high mobility group) box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.6   0.3   1.4e-24   1.3e-20       2      68 ..     129     195 ..     128     196 .. 0.98

  Alignments for each domain:
  == domain 1  score: 73.6 bits;  conditional E-value: 1.4e-24
                 -SS--HHHHHHHHHHHHHHHHSTTS-HHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHH CS
     HMG_box   2 kRplsafflfskeqraklkaenPelknaeiskklgekWkalseeeKkkYeekaekekaryekekpey 68 
                 +Rp++af+l++k+ +  lk  +P+++n++is+++g +W+++see+K ++++ a+++k ++ +++p+y
  EEA19532.1 129 PRPPNAFILYRKHYHTILKGRDPNMHNNDISVTVGSQWNNESEEVKSHFRALAAEAKRQHAQKYPNY 195
                 8****************************************************************** PP

>> HMG_box_2  HMG-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.5   0.4   1.7e-09   1.5e-05       3      72 ..     125     195 ..     123     196 .. 0.91

  Alignments for each domain:
  == domain 1  score: 25.5 bits;  conditional E-value: 1.7e-09
                 -.-..SS--HHHHHHHTTHHHHHHHT---SSHHHHTGGGHHHHHHS-HHHHHHHHHHHHHHHHHHHH-SS-- CS
   HMG_box_2   3 kpk..aarnAYalfvqemipelkrkGnpviglaevsklcsekWkalseeeKekYeekAkedkkrydrealty 72 
                 +pk  +++nA++l+ +     lk +  p +  +++s  ++++W + see K+ +   A e k +  +  ++y
  EEA19532.1 125 RPKvpRPPNAFILYRKHYHTILKGR-DPNMHNNDISVTVGSQWNNESEEVKSHFRALAAEAKRQHAQKYPNY 195
                 55544789*****************.9**********************************99998887776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (328 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1013  (0.0565006); expected 358.6 (0.02)
Passed bias filter:                      506  (0.0282224); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2210.74
//
Query:       EEA19533.1  [L=226]
Description: mating locus protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (226 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       335  (0.0186848); expected 358.6 (0.02)
Passed bias filter:                      286  (0.0159518); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.42
# Mc/sec: 1622.47
//
Query:       EEA19534.1  [L=1038]
Description: cytoskeleton assembly control protein Sla2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.2e-72  242.5   0.0    4.2e-72  242.5   0.0    3.1  3  ANTH      ANTH domain
    6.7e-56  188.8   7.7    6.7e-56  188.8   7.7    6.1  6  I_LWEQ    I/LWEQ domain
  ------ inclusion threshold ------
       0.94   10.1   3.6        6.4    7.4   3.6    2.6  1  TAF8_C    Transcription factor TFIID complex subunit 8 C-term


Domain annotation for each model (and alignments):
>> ANTH  ANTH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  242.5   0.0     7e-76   4.2e-72       1     273 [.       7     261 ..       7     263 .. 0.97
   2 ?   -7.8  10.7         3   1.8e+04     102     184 ..     345     420 ..     316     452 .. 0.54
   3 ?   -2.2   0.6      0.27   1.6e+03      82     158 ..     531     605 ..     508     639 .. 0.58

  Alignments for each domain:
  == domain 1  score: 242.5 bits;  conditional E-value: 7e-76
                 HHHHHHHHHT-SSS---HHHHHHHHHHHCSTTS-HHHHHHHHHHHCTSS.SHHHHHHHHHHHHHHHHHS-CHHHHHHHHTT-----TT---TSHHHSTH CS
        ANTH   1 dlevavvKAtshdevPpkekhvreilvltssrekvaalvwalsrrlkltrnwvvalKaLilvHklLreGhpsveqellsarrrisellnlssfddsssk 99 
                 dl+v+++KAts+       khvr+++v+t++ +k+++++wa ++ ++  +++v+++KaLi++Hk+L+eGhp +++e++ + +++ +l+++       + 
  EEA19534.1   7 DLAVNIRKATSI------GKHVRSCIVYTWD-HKSSTAFWAGMKVQPILADEVQTFKALITIHKVLQEGHPIAIREAQTHVNWLDSLMRGVA----GEG 94 
                 577788888877......69***********.*********************************************************999....799 PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHSS-...CCCS--S.....TTSHCC...C--HHHHHHHHHHHHHHHHHHHTT---GGG--SHHHHHHHHHHHHHH CS
        ANTH 100 swdysafiraYakyLderlefhrklkvdkgelereeegslvavedpner..ktlsmeklldkieklqklldrllkckptgnalsnevilaalvllvkes 196
                  ++y+++i  Y+ +L+ +l fhr+++ ++g +e+ee++sl++ +dpne+  +++++++l+d+i+++qkl++++++     n ++ne++++alv+lv+es
  EEA19534.1  95 LRGYGPLIHDYVMFLESKLHFHRNHPEFNGLFEYEEYISLKTINDPNEGyeAIMDLMNLQDQIDSFQKLIFSHFQ-----NGTNNECRISALVPLVQES 188
                 ***************************************************************************.....9999*************** PP

                 HHHHHHHHHHHHHHHHHHCCS-CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCT--GGG..S--GGGS-CHHCCCCCH CS
        ANTH 197 lklYkaineglinLlekffelskheadkaldiykrfskqfeelkeFyevckslgilrsle.iPelekippnllealee 273
                 +++Yk+i+++l+++++++ +     +++++++++r++ q+++l++Fy++c++l++l+sl+ +P+l+++pp+ll++++e
  EEA19534.1 189 YGIYKFITSMLRAMHSSTGD-----DEALEPLRSRYDAQHHRLVRFYYECSNLRYLTSLItVPKLPQDPPSLLSEDDE 261
                 ********************.....7*************************************************998 PP

  == domain 2  score: -7.8 bits;  conditional E-value: 3
                 HHHHHHHHHHHHHHHHHHHHHHHSS-...CCCS--S.....TTSHCC.C--HHHHHHHHHHHHHHHHHHH.TT---GGG--SHH CS
        ANTH 102 dysafiraYakyLderlefhrklkvdkgelereeegslvavedpnerktlsmeklldkieklqklldrll.kckptgnalsnev 184
                  ++++ +   ++L++    h+++++   ele+e+ +   a+ + ++  +l ++++ +++++l+++l++l  +++ ++n++++++
  EEA19534.1 345 EQQRLAQ--EALLRDQYAQHTQGRMA--ELEQENLN---ARAQYER-DQLLLQQYDKRMKDLEEQLNNLNgNFNLQMNSKDDQI 420
                 3444444..35566666666666666..33333333...3333333.2555555555555555555554312334444443333 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 0.27
                 -----TT---TSHHHSTHHHHHHHHHHHHHHHHHHHHHHHHHHSS-...CCCS--S.....TTSHCC.C--HHHHHH CS
        ANTH  82 rrisellnlssfddssskswdysafiraYakyLderlefhrklkvdkgelereeegslvavedpnerktlsmeklld 158
                 +++se++ + s  + +++  d  +  r+ ++ L+e+ + + +l  d++ + re+++++++ ++  e++ +++e+l  
  EEA19534.1 531 QKGSEISSMLS--KYNREMADLEEALRNKTRALEEYTSKRGELSEDHELALREKDEEIEVYKSGMEQALMELEELKL 605
                 44445544444..4566777777777777777777777777777775444444444433333333334444444433 PP

>> I_LWEQ  I/LWEQ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   9.2         3   1.8e+04     107     146 ..     309     351 ..     295     360 .. 0.60
   2 ?   -3.1   6.8       1.4   8.4e+03      72     149 ..     435     508 ..     410     512 .. 0.74
   3 ?   -1.2   0.2      0.37   2.2e+03      68     118 ..     541     595 ..     527     604 .. 0.60
   4 ?    0.5   0.0      0.11   6.3e+02      64      94 ..     724     754 ..     667     788 .. 0.59
   5 ?    2.1   0.9     0.034     2e+02      40      98 ..     809     871 ..     803     882 .. 0.62
   6 !  188.8   7.7   1.1e-59   6.7e-56       1     153 []     886    1036 ..     886    1036 .. 0.98

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 3
      I_LWEQ 107 eeldisklslvqakrqemeaqvki...lklekeLeearkkLae 146
                  e    +++  +++rq+m+aq +    ++ ++ L++++++La+
  EEA19534.1 309 AEQRRLQQQWEDQQRQQMQAQQQAqrdFEEQQRLQAEQQRLAQ 351
                 2222334445556777777777665557888889999998875 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 1.4
      I_LWEQ  72 krLeaaskaVkkatkelvkavkeakekqeeeeseeeeldisklslvqakrqemeaqvkilklekeLeearkkLaeirk 149
                 ++L +  +++++   +l++++k+ k k+ ++   +e +d+ ++ + + k++ +e    i +  ++L++ r++L   +k
  EEA19534.1 435 EALAKLYSQLRQEHLDLLQTTKALKLKAASA---QEAIDKREKLEREMKTKNLELADMIRERDRALHD-RDRLTGTNK 508
                 4667777777777777888888888777765...6888988888999999999988888888888864.666666665 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 0.37
      I_LWEQ  68 skslkrLeaaskaVkkatkelvkavkeakekqeeee....seeeeldisklslvq 118
                 sk ++++ +  +a+++ t++l + + +  e +e++e    +++ee+++ k+ + q
  EEA19534.1 541 SKYNREMADLEEALRNKTRALEEYTSKRGELSEDHElalrEKDEEIEVYKSGMEQ 595
                 4455566666666666677776666666666666554333255666655554444 PP

  == domain 4  score: 0.5 bits;  conditional E-value: 0.11
      I_LWEQ  64 adknskslkrLeaaskaVkkatkelvkavke 94 
                   +++k+ ++L +a+++ ++at ++++  ++
  EEA19534.1 724 FATDDKNSDQLINAARKPAQATIRFLRGLQS 754
                 3444555555555555555555555555555 PP

  == domain 5  score: 2.1 bits;  conditional E-value: 0.034
      I_LWEQ  40 eeLivaakevaastaqLvvasrvKadknskslkrL......eaaskaVkkatkelvkavkeakek 98 
                 +eL +aa+++ a++ +L      K  +++ +  +L       +a+ a+++a++el+ka+ e +++
  EEA19534.1 809 QELEKAANAIDAAVERLARL--RKKPRDGFTTYELrvndtiLEAALAITNAIAELIKAATESQQE 871
                 56666777777777766433..2333333333333333333788888899999999888887765 PP

  == domain 6  score: 188.8 bits;  conditional E-value: 1.1e-59
      I_LWEQ    1 ykknsqWteGLisAAkaVaaaanlLveaadavvqgkakeeeLivaakevaastaqLvvasrvKadknskslkrLeaaskaVkkatkelvkavkeake 97  
                  ykkn++WteGLisAAkaVa+++n L+e+ad+v++g++++e+Liva++ vaastaqLv+asrvKa+ +s++++rLe+askaV  a+++lv++v+++ +
  EEA19534.1  886 YKKNNRWTEGLISAAKAVATSTNRLIETADGVISGRNSPEQLIVASNDVAASTAQLVAASRVKATFMSRTQERLETASKAVGAACRSLVRQVQAIIA 982 
                  9***********************************************************************************************9 PP

      I_LWEQ   98 kqeeeeseeeeldisklslvqakrqemeaqvkilklekeLeearkkLaeirkakYr 153 
                  +++++  e e++d+skls +++k++eme+qv+il+le++L++ar++L+e+rk +Y+
  EEA19534.1  983 EKNKD--EGESVDYSKLSGHEFKVREMEQQVEILQLENALSRARTRLGEMRKISYQ 1036
                  99998..5789********************************************7 PP

>> TAF8_C  Transcription factor TFIID complex subunit 8 C-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   3.6    0.0011       6.4      22      48 ..     330     356 ..     323     356 .. 0.87

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0011
      TAF8_C  22 neretdpkkirekaaeqsrlaekaLrk 48 
                 ++  +d ++ ++ +aeq+rla++aL++
  EEA19534.1 330 QQAQRDFEEQQRLQAEQQRLAQEALLR 356
                 5578999******************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1038 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3161  (0.176307); expected 358.6 (0.02)
Passed bias filter:                      638  (0.0355848); expected 358.6 (0.02)
Passed Vit filter:                       142  (0.00792013); expected 17.9 (0.001)
Passed Fwd filter:                        44  (0.00245412); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 1.46u 0.33s 00:00:01.79 Elapsed: 00:00:00.54
# Mc/sec: 5833.24
//
Query:       EEA19535.1  [L=981]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    5.2e-05   22.5   0.0    0.00012   21.3   0.0    1.6  1  MMM1       Maintenance of mitochondrial morphology protein 1
     0.0031   17.9   0.0      0.014   15.8   0.0    2.1  2  PH_11      Pleckstrin homology domain
  ------ inclusion threshold ------
      0.062   13.8   0.0       0.47   11.0   0.0    2.4  3  PH         PH domain


Domain annotation for each model (and alignments):
>> MMM1  Maintenance of mitochondrial morphology protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.0   1.9e-08   0.00012     104     233 ..     320     447 ..     268     470 .. 0.83

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 1.9e-08
                 --HHHHHHHHHHHHHHHH-TTHHHHHHHHHHHHHHGGCS-TTEEEEEEEEEE--S---EEEEEEE.EE-TTTTSS-EEEEEEEEEEEEEEEEEEEEEEE CS
        MMM1 104 sLDWfnvLiaqtiaqfreealekdnilksLnealnseelpdyldkikvteidlGedfPifsncriikeskesekkrLeakidvdlsDtltlgietkLll 202
                    W n Li +    + ++    + + + +++ +++ ++p+++ +i + +id+G+  P + n r+ k  +   ++    + dv+ s ++ + i ++  +
  EEA19535.1 320 QTRWINALIGRLFLAMYKTPEMYEFVQTKITKKISRVQKPNFISSIALRKIDMGQGAPSITNPRL-KDLT--VDGDCTVETDVNYSGNFRIEISATARI 415
                 356********999999999999******************************************.4333..356778889999999999999877777 PP

                 SS.SSSSEE---EEEEEEEEEEEEEEEEEE.. CS
        MMM1 203 ny.PkpltavLPvalavsvvrfsgtLtvslip 233
                 +  P+     + + lav + r sg + + + p
  EEA19535.1 416 DLgPRIKARSVDLVLAVVLKRLSGHMLLRFKP 447
                 65488888899999999999999999888865 PP

>> PH_11  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   2.4e-06     0.014      17     102 ..     192     280 ..     180     283 .. 0.77
   2 ?   -4.0   0.0         3   1.8e+04      95     103 ..     320     328 ..     309     357 .. 0.63

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 2.4e-06
       PH_11  17 wfavlkdgvLeyYksekkkvvkhviklSngseaklk..adlisaalfkidsirs.sksddllleistetkifflkgdsneeteeWveal 102
                 + +vl++g L +Y++e++  v+hvi l    + +++   d+++++l  ++++   s  +d  + +   t  f+l ++s+  +e+ ++al
  EEA19535.1 192 FYIVLRHGHLMLYDDEQQIEVRHVISLTHHDVTIYGggEDIPEGELYAKRNAIClSRREDSIADLRGLTPPFYLFCQSQSAKEDFYHAL 280
                 447*************************9999998533688888888666655557777777777777777778888888888888776 PP

  == domain 2  score: -4.0 bits;  conditional E-value: 3
       PH_11  95 teeWvealk 103
                 +  W++al+
  EEA19535.1 320 QTRWINALI 328
                 444555543 PP

>> PH  PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   7.8e-05      0.47      21     102 ..     192     282 ..     176     285 .. 0.79
   2 ?   -3.6   0.0       2.8   1.7e+04      85     101 ..     312     328 ..     312     329 .. 0.80
   3 ?   -1.8   0.0      0.75   4.5e+03      73      94 ..     444     464 ..     434     465 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 7.8e-05
                 EEEEEETTEEEEESSTTCTTESSEEEEEESTTEEEEEEEC......TTSSSSTSEEEE.....EESTSSS.TEEEEEEESSHHHHHHHHHHHHH CS
          PH  21 rwfvLkdsellyykndksekdkepkgsislsncevvevva......tedpkrkfcfel.....riverng.srtyllqasseeerkeWikaiqs 102
                  ++vL+ + l++y+++   ++ e +++isl+ ++v+ ++        e   +++ ++l      i+  +g +  ++l + s++ ++++++a+ +
  EEA19535.1 192 FYIVLRHGHLMLYDDE---QQIEVRHVISLTHHDVTIYGGgedipeGELYAKRNAICLsrredSIADLRGlTPPFYLFCQSQSAKEDFYHALLK 282
                 699999999*******...*******************99988866445555666666666665555555779******************976 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 2.8
                 EEESSHHHHHHHHHHHH CS
          PH  85 lqasseeerkeWikaiq 101
                 l+as +   ++Wi+a++
  EEA19535.1 312 LHASEDHLQTRWINALI 328
                 56778888899***995 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 0.75
                 EESTSSSTEEEEEEESSHHHHH CS
          PH  73 riverngsrtyllqasseeerk 94 
                 r+++   s++++++++++ +++
  EEA19535.1 444 RFKPPP-SNRIWFCFATKPDMT 464
                 445333.599*******99996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (981 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       567  (0.0316247); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.71u 0.30s 00:00:01.01 Elapsed: 00:00:00.46
# Mc/sec: 6434.49
//
Query:       EEA19536.1  [L=379]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-24   86.2   3.1    3.8e-09   37.0   0.0    3.3  3  Ank_2     Ankyrin repeats (3 copies)
    1.2e-21   76.7   5.6    5.7e-10   39.5   0.3    4.1  4  Ank_4     Ankyrin repeats (many copies)
    2.2e-17   62.9   6.8    5.4e-05   23.4   0.2    4.4  4  Ank_5     Ankyrin repeats (many copies)
    2.8e-15   54.9   6.7     0.0071   16.8   0.1    5.4  5  Ank_3     Ankyrin repeat
    1.4e-14   53.8  16.6     0.0057   17.0   0.1    5.3  5  Ank       Ankyrin repeat


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.7   0.1   1.3e-07   0.00046      36      78 ..      19      70 ..      13      78 .. 0.62
   2 !   37.0   0.0     1e-12   3.8e-09      24      65 ..      90     139 ..      76     144 .. 0.80
   3 !   27.2   0.1   1.2e-09   4.4e-06      11      67 ..     176     242 ..     167     258 .. 0.68

  Alignments for each domain:
  == domain 1  score: 20.7 bits;  conditional E-value: 1.3e-07
       Ank_2 36 ngnleivklLleh.......ad..ndgrtpLhyAarsghleivklLlekgad 78
                ++++ +vk ++++        d  +  +t Lh+Aa +ghl+i+klLl  g d
  EEA19536.1 19 QNDVLLVKRIIKNnpvylenPDfeDGSNTSLHLAAIKGHLDILKLLLSLGHD 70
                4433446667764465554422535566888888888888888888855544 PP

  == domain 2  score: 37.0 bits;  conditional E-value: 1e-12
       Ank_2  24 k.ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsgh 65 
                 + +g taLh+Aa + + ++v lL+          dn+grtpL++Aa+s++
  EEA19536.1  90 NiDGSTALHLAAAHSHPDCVDLLCRTfphtidwNDNEGRTPLMLAAQSSN 139
                 2589********************9445596744499*********9965 PP

  == domain 3  score: 27.2 bits;  conditional E-value: 1.2e-09
       Ank_2  11 elvklLl.egadpn....k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghle 67 
                  ++ +Ll ++  ++    +  g+taLhyA   gnl++v++Ll +       ++ ++tpL y++ ++  +
  EEA19536.1 176 ATITILLsYN--ASviatDnLGNTALHYASAWGNLKAVRALLVAgtpplsPNKANHTPLDYSVTKQAAQ 242
                 4677777433..333233248999999999999999999999866787666688999999999775444 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.0   0.0   4.5e-07    0.0016       5      55 .]      13      65 ..      11      65 .. 0.86
   2 !   39.5   0.3   1.6e-13   5.7e-10       2      54 ..      46     112 ..      45     113 .. 0.89
   3 !    5.3   0.0    0.0085        30      27      48 ..     122     140 ..     115     143 .. 0.79
   4 !   31.5   0.1   5.2e-11   1.9e-07       8      55 .]     169     215 ..     167     215 .. 0.95

  Alignments for each domain:
  == domain 1  score: 19.0 bits;  conditional E-value: 4.5e-07
       Ank_4  5 LhyaaisgrlelvrlLlekgadinaqdn..rsGetalhiAakrgnveilklLl 55
                L +a+ ++++ lv++++ +++   + ++  +  +t lh Aa +g+++ilklLl
  EEA19536.1 13 LRRAILQNDVLLVKRIIKNNPVYLENPDfeDGSNTSLHLAAIKGHLDILKLLL 65
                67899999999******98887777744666699******************8 PP

  == domain 2  score: 39.5 bits;  conditional E-value: 1.6e-13
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgad..............inaqdnrsGetalhiAakrgnveilklL 54 
                 +t Lh aai+g+l++++lLl+ g d              +  ++n++G talh Aa +++++++ lL
  EEA19536.1  46 NTSLHLAAIKGHLDILKLLLSLGHDsctpnidrtgydsaPGISLNIDGSTALHLAAAHSHPDCVDLL 112
                 588********************9999999777766666555599*******************998 PP

  == domain 3  score: 5.3 bits;  conditional E-value: 0.0085
       Ank_4  27 inaqdnrsGetalhiAakrgnv 48 
                 +n    ++G+t+l  Aa+ +n+
  EEA19536.1 122 WND---NEGRTPLMLAAQSSNP 140
                 444...58*********99886 PP

  == domain 4  score: 31.5 bits;  conditional E-value: 5.2e-11
       Ank_4   8 aaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 a++s+++ ++ +Ll+++a++ a+ ++ G+talh+A  +gn+++++ Ll
  EEA19536.1 169 AMASEDIATITILLSYNASVIAT-DNLGNTALHYASAWGNLKAVRALL 215
                 888999*****************.888*******************97 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.0   2.7e-07   0.00097      11      36 ..      40      65 ..      36      84 .. 0.84
   2 !   17.3   0.3   1.2e-06    0.0044      12      56 .]      89     134 ..      81     134 .. 0.85
   3 !    8.3   0.0   0.00083         3      10      25 ..     121     136 ..     114     141 .. 0.88
   4 !   23.4   0.2   1.5e-08   5.4e-05       1      55 [.     181     234 ..     181     235 .. 0.94

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 2.7e-07
       Ank_5 11 rldgggntpLhvAakygaadvvrlLl 36
                + + g+nt Lh+Aa +g++d+++lLl
  EEA19536.1 40 DFEDGSNTSLHLAAIKGHLDILKLLL 65
                5678999******************9 PP

  == domain 2  score: 17.3 bits;  conditional E-value: 1.2e-06
       Ank_5  12 ldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltaldlA 56 
                 l+ +g t+Lh+Aa + ++d+v lL+  ++  ++  d++G+t+l lA
  EEA19536.1  89 LNIDGSTALHLAAAHSHPDCVDLLCrTFPHTIDWNDNEGRTPLMLA 134
                 556788********************88888888888899998665 PP

  == domain 3  score: 8.3 bits;  conditional E-value: 0.00083
       Ank_5  10 nrldgggntpLhvAak 25 
                 +++d++g tpL++Aa 
  EEA19536.1 121 DWNDNEGRTPLMLAAQ 136
                 799***********95 PP

  == domain 4  score: 23.4 bits;  conditional E-value: 1.5e-08
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldl 55 
                 Ll++  a+v ++d+ gnt+Lh+A+  g++  vr Ll  g  +   ++ + t+ld+
  EEA19536.1 181 LLSYN-ASVIATDNLGNTALHYASAWGNLKAVRALLVAGTPPLSPNKANHTPLDY 234
                 66776.99**********************************************8 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0      0.69   2.5e+03       8      26 ..      15      33 ..      13      36 .. 0.81
   2 !   16.8   0.1     2e-06    0.0071       3      25 ..      46      70 ..      45      76 .. 0.83
   3 !   14.8   0.0   8.8e-06     0.032       1      23 [.      92     114 ..      92     123 .. 0.85
   4 !    8.9   0.0   0.00072       2.6       1      15 [.     126     140 ..     126     145 .. 0.88
   5 !   13.2   0.0   2.9e-05       0.1       2      23 ..     195     216 ..     194     222 .. 0.90

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.69
       Ank_3  8 lAarsgnleivkfLlenkg 26
                +A++++++ +vk +++n+ 
  EEA19536.1 15 RAILQNDVLLVKRIIKNNP 33
                6899999999*****9654 PP

  == domain 2  score: 16.8 bits;  conditional E-value: 2e-06
       Ank_3  3 etpLhlAarsgnleivkfLle..nk 25
                +t LhlAa  g+l+i+k+Ll   + 
  EEA19536.1 46 NTSLHLAAIKGHLDILKLLLSlgHD 70
                79******************95444 PP

  == domain 3  score: 14.8 bits;  conditional E-value: 8.8e-06
       Ank_3   1 nGetpLhlAarsgnleivkfLle 23 
                 +G t+LhlAa + +++ v++L++
  EEA19536.1  92 DGSTALHLAAAHSHPDCVDLLCR 114
                 699******************99 PP

  == domain 4  score: 8.9 bits;  conditional E-value: 0.00072
       Ank_3   1 nGetpLhlAarsgnl 15 
                 +G+tpL+lAa s n+
  EEA19536.1 126 EGRTPLMLAAQSSNP 140
                 69*********9987 PP

  == domain 5  score: 13.2 bits;  conditional E-value: 2.9e-05
       Ank_3   2 GetpLhlAarsgnleivkfLle 23 
                 G+t+Lh+A   gnl+ v++Ll 
  EEA19536.1 195 GNTALHYASAWGNLKAVRALLV 216
                 9*******************95 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.5     3e-06     0.011       3      29 ..      46      76 ..      45      78 .. 0.76
   2 !   16.5   0.2   2.3e-06    0.0083       1      21 [.      92     112 ..      92     120 .. 0.89
   3 !   11.7   0.9   7.6e-05      0.27       2      32 .]     127     193 ..     126     193 .. 0.54
   4 !   17.0   0.1   1.6e-06    0.0057       2      24 ..     195     218 ..     194     229 .. 0.85
   5 ?   -2.0   0.0       1.7   6.1e+03       3      11 ..     229     237 ..     227     251 .. 0.70

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 3e-06
                BBHHHHHHHHTTHHHHHHHH...TT.TSTTC CS
         Ank  3 nTPLHlAatngkkriiklLL...hG.Anlna 29
                nT LHlAa  g+++i+klLL   h  + +n+
  EEA19536.1 46 NTSLHLAAIKGHLDILKLLLslgHDsCTPNI 76
                789*****9999*******953432244665 PP

  == domain 2  score: 16.5 bits;  conditional E-value: 2.3e-06
                 TSBBHHHHHHHHTTHHHHHHH CS
         Ank   1 dGnTPLHlAatngkkriiklL 21 
                 dG T+LHlAa   +++++ lL
  EEA19536.1  92 DGSTALHLAAAHSHPDCVDLL 112
                 8*********889999**987 PP

  == domain 3  score: 11.7 bits;  conditional E-value: 7.6e-05
                 SBBHHHHHH...........HHTT..........................HHHHHHHH.TTTSTTCBTT CS
         Ank   2 GnTPLHlAa...........tngk..........................kriiklLL.hGAnlnaldn 32 
                 G+TPL+lAa           t  +                             i  LL + A++ a+dn
  EEA19536.1 127 GRTPLMLAAqssnpshapvsT--NssthippptgrrpravstnsamasedIATITILLsYNASVIATDN 193
                 9******97554333333332..0334454455555555555555555333355557855788888886 PP

  == domain 4  score: 17.0 bits;  conditional E-value: 1.6e-06
                 SBBHHHHHHHHTTHHHHHHHH.TT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hG 24 
                 GnT+LH+A+  g++  +++LL  G
  EEA19536.1 195 GNTALHYASAWGNLKAVRALLvAG 218
                 9********99*******999788 PP

  == domain 5  score: -2.0 bits;  conditional E-value: 1.7
                 BBHHHHHHH CS
         Ank   3 nTPLHlAat 11 
                 +TPL + +t
  EEA19536.1 229 HTPLDYSVT 237
                 69*999764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (379 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       511  (0.0285013); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.49
# Mc/sec: 2349.78
//
Query:       EEA19537.1  [L=481]
Description: ubiquitin thiolesterase (OtuB1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.5e-56  190.0   0.0    5.6e-56  189.7   0.0    1.1  1  Peptidase_C65  Peptidase C65 Otubain


Domain annotation for each model (and alignments):
>> Peptidase_C65  Peptidase C65 Otubain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  189.7   0.0   3.1e-60   5.6e-56       3     246 .]      82     322 ..      80     322 .. 0.96

  Alignments for each domain:
  == domain 1  score: 189.7 bits;  conditional E-value: 3.1e-60
                    GCCSXSB---EETHHHHTTTTT.THHHHHHHHHHHTTEEEEE-B--SSTHHHHHHHHHHHHHHHH-HH..HHHHHHHHHHHHHHHHHHTT--HHHH CS
  Peptidase_C65   3 vkqkplvsekkplsaLakeyek.naailkkikllsekYssiRrvrgDGnCfyRaflfsylellleskdkaevsrikerveklkealeslgfdeevv 97 
                    + q +lvs k++++++ +ey++ ++a++ k+++l  + ++ R+++gDGnC++Ra++f+y+e l   +d+ +v+ +  r+++++  l+++g +e ++
     EEA19537.1  82 EVQGALVSPKQSSQIISAEYSNaDPAFVTKTNALAVTHPFTRTMKGDGNCGWRAVAFGYFENLFFLRDTIKVQSELSRIKSMNALLDQVGHQEYLY 177
                    56889***************************************************************99************************** PP

                    HHHHHHHHHHHHHHHTTSS-HH....HHHHHHTSHHHHHHHHHHHHHHHHHHHHHTHHHHGGGS-TT--HHHHHHHHTSSTT--B-HHHHHHHHHH CS
  Peptidase_C65  98 edfleaflellkkiekkteeseekaeellkafneqeesdyivvflRlltsaelkthadeyepFldelstveeFceqevepvnkEaDnvqitaLaea 193
                    e+f++a++e   ++ +  ++ +  ++ l++ fn+ ++s++i++++Rllt a++k ++  y++Fl++   v+++c + +ep + E+D+v+++aL++ 
     EEA19537.1 178 ETFVDATEETFGHVIDAIQKGVPDESFLVDIFNDFSQSMSIITHFRLLTGAWMKLNQPRYQAFLSM--PVDQYCVTRIEPAKTEIDEVGLQALVDS 271
                    *********999999999999888899*************************************99..9**************************9 PP

                    T....T--EEEEESSSSGBSTTSEEEEES-S....SS-S--SEEEEEETBEEEEEEE CS
  Peptidase_C65 194 l....gvkvrVeyldrsvegesvnahafpeeaqkseeeqapeitLlYrpgHYDiLyk 246
                    +    +++v++ yldrs +g+ v+ h         + ++  +i LlYrpgHYDiLy+
     EEA19537.1 272 ViegsDIAVEILYLDRS-QGDAVTPHLLT-----PNRQNLATIRLLYRPGHYDILYS 322
                    99999************.********998.....5689999**************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (481 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       392  (0.021864); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 3243.23
//
Query:       EEA19538.1  [L=498]
Description: COP9 signalosome subunit 2 (CsnB), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.6e-21   75.3   0.5    4.6e-21   75.3   0.5    1.9  2  PCI       PCI domain
     0.0018   18.1   0.4      0.018   14.8   0.1    2.8  3  TPR_1     Tetratricopeptide repeat
     0.0024   17.8   3.0       0.17   12.0   0.0    4.1  4  TPR_7     Tetratricopeptide repeat
     0.0058   16.3   0.4      0.022   14.5   0.1    2.2  2  TPR_11    TPR repeat
  ------ inclusion threshold ------
      0.016   15.2   0.1      0.016   15.2   0.1    3.3  4  TPR_2     Tetratricopeptide repeat
      0.021   15.1   1.3       0.46   10.8   0.0    3.3  4  TPR_12    Tetratricopeptide repeat
      0.071   14.0   2.0        1.5    9.8   0.0    3.3  3  TPR_14    Tetratricopeptide repeat
       0.21   11.9   1.7        1.8    9.0   0.1    2.8  2  TPR_8     Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> PCI  PCI domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.1       4.7     1e+04      26      44 ..     161     179 ..     136     187 .. 0.66
   2 !   75.3   0.5     2e-24   4.6e-21       2     104 ..     315     416 ..     314     417 .. 0.98

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 4.7
                 HHHHHHHTTHHHHHHHHHH CS
         PCI  26 eeelladdglaqllesLek 44 
                  + +l++++ aql ++L++
  EEA19538.1 161 AKLWLDRREFAQLTKKLRE 179
                 4446666666666666665 PP

  == domain 2  score: 75.3 bits;  conditional E-value: 2e-24
                 HHHHHHHHHHHTSHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHCESEEEHHHHHHHHTSSHHHHHHHHHHHHHTTSSSEEEETTTTE CS
         PCI   2 sysdllkalrsgnlsgfseelkdleeelladdglaqllesLekkvrerllrqvskiyssislerlaklldlsvdevEkilvklIrdgeirakidqesgi 100
                 +++dl+ a+++ ++  ++ +l+++ +++lad+++a+ ++++ +++r++++++++ +y++++l+ ++k++++s +ev++il  lI d++++akidqe+g+
  EEA19538.1 315 AMTDLVDAYQRDDIHTYEDILRKN-HDVLADPFIAENIDEVSRNMRTKAVIKLIAPYTRFTLSFISKQIKISISEVQEILGFLIMDKKLNAKIDQENGT 412
                 689*********************.************************************************************************** PP

                 EEEC CS
         PCI 101 vvfk 104
                 vv++
  EEA19538.1 413 VVVE 416
                 **97 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.1   8.2e-06     0.018      12      26 ..      81      95 ..      75      98 .. 0.90
   2 ?   -1.5   0.0       1.2   2.7e+03      23      30 ..     222     229 ..     220     231 .. 0.77
   3 ?   -1.5   0.0       1.2   2.7e+03       8      24 ..     247     263 ..     247     266 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 8.2e-06
                HHTT-HHHHHHHHHH CS
       TPR_1 12 fklgkydeAleyyek 26
                fklg+yd+A+e+y++
  EEA19538.1 81 FKLGRYDDAIEHYRE 95
                8************97 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1.2
                 HHHHHHHH CS
       TPR_1  23 yyekALel 30 
                  ye+AL++
  EEA19538.1 222 LYERALRV 229
                 69999986 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 1.2
                 HHHHHHTT-HHHHHHHH CS
       TPR_1   8 GnayfklgkydeAleyy 24 
                 G ++++ +++++A  ++
  EEA19538.1 247 GKMHMSEENWEQAQSDF 263
                 678899999***98887 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.0   7.8e-05      0.17      11      29 ..      82      98 ..      81     112 .. 0.84
   2 ?   -1.2   0.1       1.3   2.8e+03       5      18 ..     160     173 ..     159     187 .. 0.80
   3 ?    2.4   0.0      0.09     2e+02       9      34 ..     210     235 ..     208     237 .. 0.72
   4 ?   -0.3   0.0      0.62   1.4e+03       6      20 ..     247     261 ..     247     272 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 7.8e-05
       TPR_7 11 rlGdyeeAielyeqsLalt 29
                +lG+y++Aie+y+++L  t
  EEA19538.1 82 KLGRYDDAIEHYRELL--T 98
                79************55..3 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 1.3
       TPR_7   5 LarlysrlGdyeeA 18 
                 La l+ ++++++++
  EEA19538.1 160 LAKLWLDRREFAQL 173
                 89999999999876 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.09
       TPR_7   9 ysrlGdyeeAielyeqsLaltkdped 34 
                 y +  + +++  lye++L+++++  +
  EEA19538.1 210 YAETKNNKRLKALYERALRVRSAVPH 235
                 555666778889****8888777655 PP

  == domain 4  score: -0.3 bits;  conditional E-value: 0.62
       TPR_7   6 arlysrlGdyeeAie 20 
                 + ++ ++ ++e+A +
  EEA19538.1 247 GKMHMSEENWEQAQS 261
                 6789999*****965 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.1   9.6e-06     0.022       4      23 ..      80      99 ..      74     108 .. 0.87
   2 ?   -3.4   0.0       3.7   8.2e+03      16      23 ..     222     229 ..     221     231 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 9.6e-06
      TPR_11  4 yyeqGkyeeAieaYkkAlkl 23
                 +++G+y++Aie+Y++ l +
  EEA19538.1 80 EFKLGRYDDAIEHYRELLTY 99
                79*************98876 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 3.7
      TPR_11  16 aYkkAlkl 23 
                  Y++Al+ 
  EEA19538.1 222 LYERALRV 229
                 59999986 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   0.1   7.3e-06     0.016      12      29 ..      81      98 ..      78     102 .. 0.89
   2 ?   -3.6   0.1         8   1.8e+04      18      27 ..     127     136 ..     125     139 .. 0.73
   3 ?   -2.2   0.1       2.8   6.4e+03      22      29 ..     221     228 ..     220     229 .. 0.74
   4 ?   -0.8   0.0         1   2.3e+03       8      24 ..     247     263 ..     247     263 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 7.3e-06
       TPR_2 12 yklgdyeeAleafekAle 29
                +klg+y++A+e++++ l 
  EEA19538.1 81 FKLGRYDDAIEHYRELLT 98
                89*************996 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 8
       TPR_2  18 eeAleafekA 27 
                 e+A +++e+ 
  EEA19538.1 127 EKAYHCMEEF 136
                 7899999885 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 2.8
       TPR_2  22 eafekAle 29 
                 +++e+Al+
  EEA19538.1 221 ALYERALR 228
                 57899886 PP

  == domain 4  score: -0.8 bits;  conditional E-value: 1
       TPR_2   8 GlayyklgdyeeAleaf 24 
                 G+ ++   ++e+A  +f
  EEA19538.1 247 GKMHMSEENWEQAQSDF 263
                 67899999*****8776 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00021      0.46      13      31 ..      80      98 ..      76     111 .. 0.79
   2 ?   -1.4   0.0       1.3   2.9e+03      26      46 ..     177     197 ..     160     200 .. 0.82
   3 ?   -0.3   0.0      0.61   1.4e+03      24      36 ..     221     233 ..     208     239 .. 0.68
   4 ?   -0.9   0.0      0.96   2.1e+03      13      28 ..     257     272 ..     247     278 .. 0.56

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00021
      TPR_12 13 lrrlgrydeAlellekale 31
                +++lgryd+A+e++++ l 
  EEA19538.1 80 EFKLGRYDDAIEHYRELLT 98
                5788888888888888776 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 1.3
      TPR_12  26 lekaleiarrllGpdhpltat 46 
                 l++ +++++r  G+d p   t
  EEA19538.1 177 LRELHRACQREDGTDDPSKGT 197
                 67889999*****99998765 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.61
      TPR_12  24 ellekaleiarrl 36 
                 +l+e+al++++++
  EEA19538.1 221 ALYERALRVRSAV 233
                 6777777777666 PP

  == domain 4  score: -0.9 bits;  conditional E-value: 0.96
      TPR_12  13 lrrlgrydeAlellek 28 
                 ++++ ++ e+++++++
  EEA19538.1 257 EQAQSDFFESFRNYDE 272
                 3444444444444444 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0   0.00069       1.5       4      28 ..      73      97 ..      70     106 .. 0.86
   2 ?   -1.4   0.1       2.7   5.9e+03       7      31 ..     160     184 ..     157     191 .. 0.71
   3 ?    1.5   0.1      0.32   7.2e+02       7      29 ..     206     228 ..     200     235 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00069
      TPR_14  4 llalaeallalGdpdeAiallrral 28
                l+++ ++++ lG++d+Ai+++r++l
  EEA19538.1 73 LKQAIKLEFKLGRYDDAIEHYRELL 97
                567888999*************997 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 2.7
      TPR_14   7 laeallalGdpdeAiallrralala 31 
                 la++ l ++++++  + lr++ +++
  EEA19538.1 160 LAKLWLDRREFAQLTKKLRELHRAC 184
                 7777888888887777777766654 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.32
      TPR_14   7 laeallalGdpdeAiallrrala 29 
                   + +++  + ++  al++ral+
  EEA19538.1 206 EIQMYAETKNNKRLKALYERALR 228
                 467899999999*********98 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.1   0.00081       1.8      12      29 ..      81      98 ..      75      99 .. 0.89
   2 ?    0.9   0.2      0.31   7.1e+02      10      31 ..     209     230 ..     208     232 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00081
                HHTT-HHHHHHHHHHHHH CS
       TPR_8 12 lklgdyeeAkeyyekale 29
                +klg+y+ A+e y++ l+
  EEA19538.1 81 FKLGRYDDAIEHYRELLT 98
                79************9986 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.31
                 HHHHTT-HHHHHHHHHHHHHHH CS
       TPR_8  10 iylklgdyeeAkeyyekaleld 31 
                  y ++++ +  k+ ye+al+ +
  EEA19538.1 209 MYAETKNNKRLKALYERALRVR 230
                 58899999999*******9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (498 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       943  (0.0525964); expected 358.6 (0.02)
Passed bias filter:                      568  (0.0316805); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.45
# Mc/sec: 3314.72
//
Query:       EEA19539.1  [L=398]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-26   92.7   0.8    2.3e-26   92.7   0.8    4.0  3  CWC25     Pre-mRNA splicing factor
    3.1e-12   46.5  10.0    3.1e-12   46.5  10.0    3.5  5  Cir_N     N-terminal domain of CBF1 interacting co-repressor 


Domain annotation for each model (and alignments):
>> CWC25  Pre-mRNA splicing factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   1.4      0.05   4.5e+02      23      48 ..      27      52 ..      12      66 .. 0.59
   2 !   92.7   0.8   2.6e-30   2.3e-26       2     102 .]      65     156 ..      64     156 .. 0.83
   3 ?   -5.8   7.9         2   1.8e+04      63      63 ..     317     317 ..     161     379 .. 0.72

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.05
       CWC25 23 eeyllGKkrvdkllegkdkaekkkka 48
                +  l+++kr+d+++ + +++++  + 
  EEA19539.1 27 KKALEERKRIDQMMRERQEERQMLEI 52
                44578889999999886664444322 PP

  == domain 2  score: 92.7 bits;  conditional E-value: 2.6e-30
       CWC25   2 aerleWMYegpke.agaaeeeneeyllGKkrvdkllegkdkaekkkkakaskaesaaeqggaarlekvansardtanklreDPllaIkkqeqealkall 99 
                  +r++WMY+gp++ +  ++ee+e yllGK+r+d l++g+++++ +k +        a+q++  +l+++ n+ardta+k+reDP+laIkkqeq+a++a++
  EEA19539.1  65 LNRVDWMYSGPSSgQLGTTEEMEGYLLGKRRIDGLIKGSENQKLEK-S--------AAQDSFMALQNA-NTARDTAAKIREDPMLAIKKQEQAAYEAMM 153
                 58*********6643349999*****************87765555.2........234445556666.8***************************** PP

       CWC25 100 knP 102
                 ++P
  EEA19539.1 154 NDP 156
                 *98 PP

  == domain 3  score: -5.8 bits;  conditional E-value: 2
       CWC25  63 a 63 
                 a
  EEA19539.1 317 A 317
                 1 PP

>> Cir_N  N-terminal domain of CBF1 interacting co-repressor CIR
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.5  10.0   3.4e-16   3.1e-12       1      37 []      10      46 ..      10      46 .. 0.99
   2 ?   -3.6   0.4       1.5   1.4e+04      25      31 ..     142     148 ..     141     151 .. 0.53
   3 ?   -3.7   0.6       1.6   1.4e+04      21      28 ..     174     181 ..     173     190 .. 0.42
   4 ?   -3.7   0.4       1.6   1.4e+04      28      31 ..     313     316 ..     309     324 .. 0.51
   5 ?   -3.8   1.8       1.8   1.6e+04      25      28 ..     345     348 ..     335     355 .. 0.51

  Alignments for each domain:
  == domain 1  score: 46.5 bits;  conditional E-value: 3.4e-16
                SS-TTSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
       Cir_N  1 SWHPgllkNqerVWkaEqkaleEkkkieerkkeieeE 37
                SW+P l kNqe+ W aE+kaleE+k+i+++++e++eE
  EEA19539.1 10 SWNPVLQKNQEKTWLAEKKALEERKRIDQMMRERQEE 46
                9***********************************9 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 1.5
                 HHHHHHH CS
       Cir_N  25 kkieerk 31 
                 kk+e+ +
  EEA19539.1 142 KKQEQAA 148
                 5555544 PP

  == domain 3  score: -3.7 bits;  conditional E-value: 1.6
                 HHHHHHHH CS
       Cir_N  21 leEkkkie 28 
                 ++E++  +
  EEA19539.1 174 EKERRHHR 181
                 33444333 PP

  == domain 4  score: -3.7 bits;  conditional E-value: 1.6
                 HHHH CS
       Cir_N  28 eerk 31 
                 eer+
  EEA19539.1 313 EERA 316
                 3333 PP

  == domain 5  score: -3.8 bits;  conditional E-value: 1.8
                 HHHH CS
       Cir_N  25 kkie 28 
                 k ++
  EEA19539.1 345 KAER 348
                 2222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (398 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1967  (0.109711); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        83  (0.00462937); expected 17.9 (0.001)
Passed Fwd filter:                        25  (0.00139439); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.97u 0.32s 00:00:01.29 Elapsed: 00:00:00.52
# Mc/sec: 2299.24
//
Query:       EEA19540.1  [L=487]
Description: proteasome regulatory particle subunit (RpnE), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.8e-23   81.7   0.0    2.2e-22   79.6   0.0    2.1  1  PCI       PCI domain
    4.7e-16   58.6   0.6    1.3e-15   57.2   0.6    1.8  1  RPN5_C    26S proteasome regulatory subunit RPN5 C-terminal d
  ------ inclusion threshold ------
      0.039   14.2   0.6        1.9    8.8   0.2    2.8  2  KORA      TrfB plasmid transcriptional repressor


Domain annotation for each model (and alignments):
>> PCI  PCI domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.6   0.0   3.6e-26   2.2e-22       5     104 ..     328     438 ..     325     439 .. 0.95

  Alignments for each domain:
  == domain 1  score: 79.6 bits;  conditional E-value: 3.6e-26
                 HHHHHHHHTSHHHHHHHHHHH...........HHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHCESEEEHHHHHHHHTSSHHHHHHHHHHHHHTTSSSE CS
         PCI   5 dllkalrsgnlsgfseelkdl...........eeelladdglaqllesLekkvrerllrqvskiyssislerlaklldlsvdevEkilvklIrdgeira 92 
                 +llk ++  +l++++e+ +++           +e+  +d++ ++ +++L+k+v+e+++r ++k+y++i+ +rl++lldl++de+Ek++++l+ ++ i+a
  EEA19540.1 328 RLLKLFTVHELMRWPEIAEKFgphltstdvfdKEQNPNDPDAYTRWQDLRKRVIEHNVRVIAKYYTRIQTSRLTQLLDLTEDETEKYISDLVTSKTIYA 426
                 79************************999998888888899999******************************************************* PP

                 EEETTTTEEEEC CS
         PCI  93 kidqesgivvfk 104
                 kid+++++++f 
  EEA19540.1 427 KIDRPARVINFA 438
                 *********996 PP

>> RPN5_C  26S proteasome regulatory subunit RPN5 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.2   0.6   2.2e-19   1.3e-15       1      33 []     444     476 ..     444     476 .. 0.97

  Alignments for each domain:
  == domain 1  score: 57.2 bits;  conditional E-value: 2.2e-19
      RPN5_C   1 NevLNeWssninkLLelvekttHLInKEeMvhk 33 
                 ++vLNeWs n+ +LL l+e+++HLI+KEeM+++
  EEA19540.1 444 DDVLNEWSGNMRSLLGLLERIDHLITKEEMMAR 476
                 79*****************************86 PP

>> KORA  TrfB plasmid transcriptional repressor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   0.2   0.00032       1.9       7      52 ..      17      62 ..      12      66 .. 0.92
   2 ?    2.4   0.0     0.032   1.9e+02      40      60 ..      84     104 ..      77     119 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00032
        KORA  7 eeiikgleelaeqtveiargvLVegkkqadvatelgltkqavsqav 52
                ++ii+  +ela+++v++a + L   +kqa  a  l+ t + +  +v
  EEA19540.1 17 DKIIPEAQELAKSNVQAAIDKLSLLEKQARQASDLATTSRTIVAIV 62
                6899**********************************99998887 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.032
        KORA  40 elgltkqavsqavkrvwaaha 60 
                 + g  kqa  ++v++v++  +
  EEA19540.1  84 KHGQLKQATTKMVQKVMEFLE 104
                 5677899*********98655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (487 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1331  (0.0742373); expected 358.6 (0.02)
Passed bias filter:                      556  (0.0310112); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.48
# Mc/sec: 3041.85
//
Query:       EEA19541.1  [L=326]
Description: dihydrofolate reductase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.3e-67  225.9   0.0    5.6e-67  225.5   0.0    1.1  1  FSH1           Serine hydrolase (FSH1)
    1.2e-06   29.3   0.7    4.9e-06   27.3   0.7    1.8  1  Abhydrolase_6  Alpha/beta hydrolase family


Domain annotation for each model (and alignments):
>> FSH1  Serine hydrolase (FSH1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  225.5   0.0   6.2e-71   5.6e-67       4     210 ..      57     297 ..      53     299 .. 0.97

  Alignments for each domain:
  == domain 1  score: 225.5 bits;  conditional E-value: 6.2e-71
        FSH1   4 kkkiLcLhGytqsgeiFraktsalrkllkk....lnvelvyldaplelaekadlpkseseeee.kseeeeesraWfrkkde.kneyegleesldavkdy 96 
                 ++kiL+LhG+tqsg++Frakt+al k+++k    ++v++ y+++pl+l ++ d+p+++s++++ k+ ee e+++W+r++ + + +y+g+e++l++v+ +
  EEA19541.1  57 PLKILMLHGFTQSGSLFRAKTGALTKAITKafplHTVSFSYPTGPLRL-NPFDVPGYTSSNDNdKEVEEPEMYGWWRRPSTtPPTYKGIEDGLATVAAT 154
                 68**********************************************.********9988887999***********999899*************** PP

        FSH1  97 ikengpfdGiiGFSqGaalaallaslleellkea........................shpslkfailvsGfkleepkyeeyy.eedkiqtptLhvlGe 170
                 +k++gpfdG++GFSqGa+l+a++aslle+++ ++                        ++p+lkfai++sGfk+ +p+  ++y  +++i+tp LhvlG+
  EEA19541.1 155 LKNEGPFDGVVGFSQGACLTAMVASLLEPGRSDSfsaaaaapgdgvqfpesfypgntgNQPPLKFAIVYSGFKVADPRWGALYdVQRPITTPLLHVLGT 253
                 *******************************999*************************************************99************** PP

        FSH1 171 lDtvvdeerseaLaeafkns....skvlkHpggHfvPnkkeyvd 210
                 lD++v e++s+ L+ea++ +     kv++HpggHfvP++k y++
  EEA19541.1 254 LDALVIEAMSRGLIEACAGDpekeGKVVFHPGGHFVPSQKTYLE 297
                 ******************9999999***************9986 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.7   5.4e-10   4.9e-06       1     181 [.      60     256 ..      60     299 .. 0.51

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 5.4e-10
                    EEEE--GC.....GC..HHHHHHHHCCT..CEEE............EE--TTST...................S-GGCS--HHHCHHHHHHHCCTT CS
  Abhydrolase_6   1 vlllHGagssassWl..vapLaallaag..vhvl............apDlpGhG...................rsdpppldledladlaalldela 61 
                    +l+lHG+  s+s ++  ++ L ++ ++    h++             +D pG+                    r+++ p ++  ++d +a++++  
     EEA19541.1  60 ILMLHGFTQSGSLFRakTGALTKAITKAfpLHTVsfsyptgplrlnPFDVPGYTssndndkeveepemygwwrRPSTTPPTYKGIEDGLATVAATL 155
                    79************4467777665566633344533333333333366666773567788888888888888877999999988666666666666 PP

                    ..TTSE.EEEEETCHHHHHHHHHHCC..EEEEES-..----TTT..........S----TTHHHHHHTT-CCCCHCCHS-HSCCCCHHHCCCCHCH CS
  Abhydrolase_6  62 agggpv.vlvGHSlGGalalaaaplalvvgvlldppptalpagl..........laaalelllallallrllawlsreplprlfladedadaawra 146
                    ++ gp+  +vG S+G+ l ++   +a     ll+p   +  +++          ++++ +++ + +++ ++l +     ++ +f     ad++w+a
     EEA19541.1 156 KNEGPFdGVVGFSQGACLTAM---VA----SLLEP---GRSDSFsaaaaapgdgVQFPESFYPGNTGNQPPLKFAI--VYS-GFKV---ADPRWGA 235
                    566899999********9999...77....77777...33333311100000002222222222222222222221..111.1111...2233333 PP

                    CCCGHHHHCCHHCHTTCCHHTT-TTGC.EEECTT-C CS
  Abhydrolase_6 147 rlarlaallaglgllpaaawadlpvpl.lvlggeDp 181
                     ++  ++ ++               pl +vlg+ D+
     EEA19541.1 236 LYDVQRPITT---------------PLlHVLGTLDA 256
                    3333332222...............22122244444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (326 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       344  (0.0191868); expected 358.6 (0.02)
Passed bias filter:                      294  (0.016398); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2348.74
//
Query:       EEA19542.1  [L=129]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.11   10.6   0.0       0.13   10.3   0.0    1.0  1  Patched   Patched family


Domain annotation for each model (and alignments):
>> Patched  Patched family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   7.2e-06      0.13     511     592 ..      11      92 ..       8     101 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 7.2e-06
     Patched 511 dltikesrdrleelveefentpyalgk..kstkfwlreyekflkqseleveeledeeeew.skeelesflkaaenslwkkdlvwd 592
                 d++ +++ d++ el+++fen p +  +  + t f+l+++ +  ++   e    ++++      e+ ++ +++ +++ + + l  d
  EEA19542.1  11 DFNAQKMDDQMGELLDAFENHPLMQPPvaHPTLFFLFDFIRNTRK---ELRAIDIQKLREgDAEAKKQIMDVIGRNGLTSALIND 92 
                 789999****************9987522679********94444...6666666665444788889999999988887776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (129 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       472  (0.0263261); expected 358.6 (0.02)
Passed bias filter:                      434  (0.0242066); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.28s 00:00:00.67 Elapsed: 00:00:00.42
# Mc/sec: 914.60
//
Query:       EEA19543.1  [L=82]
Description: 40S ribosomal protein S27, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      1e-28   98.8   6.7    1.3e-28   98.5   6.7    1.1  1  Ribosomal_S27e  Ribosomal protein S27
  ------ inclusion threshold ------
       0.52   10.3   5.9          2    8.4   4.2    2.3  2  zf-C2HC5        Putative zinc finger motif, C2HC5-type


Domain annotation for each model (and alignments):
>> Ribosomal_S27e  Ribosomal protein S27
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.5   6.7   1.4e-32   1.3e-28       1      55 []      28      82 .]      28      82 .] 0.99

  Alignments for each domain:
  == domain 1  score: 98.5 bits;  conditional E-value: 1.4e-32
                    -S--EEEEE-TTTS-EEEEESS-SS-EEESSSTCEEEEECSSSEEESSCEEEEES CS
  Ribosomal_S27e  1 prskFldvkCpdCenetvvFshaatvvkCisCgkvLvePtGGkaklkaqilerlk 55
                    prs+F+dvkCp+C+ +t+vFsha+tvv C  C++vL++PtGGka+l++++++r+k
      EEA19543.1 28 PRSFFMDVKCPGCFTITTVFSHAQTVVICAGCSTVLCQPTGGKARLTEGCSFRRK 82
                    89***************************************************97 PP

>> zf-C2HC5  Putative zinc finger motif, C2HC5-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.0     0.041   3.7e+02       7      18 ..      15      26 ..      13      29 .. 0.83
   2 ?    8.4   4.2   0.00023         2       8      39 ..      44      79 ..      36      81 .. 0.77

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.041
    zf-C2HC5  7 qatrHpLleaap 18
                +a++H+L  ++p
  EEA19543.1 15 EARKHKLKMLVP 26
                69*****88776 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.00023
    zf-C2HC5  8 atrHpLleaapnClnCGkiiCakegls....kpCsf 39
                 t    ++++ +C  C  ++C+  g +    + Csf
  EEA19543.1 44 TTVFSHAQTVVICAGCSTVLCQPTGGKarltEGCSF 79
                55555567899***********99887666677877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (82 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       663  (0.0369792); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.35u 0.27s 00:00:00.62 Elapsed: 00:00:00.41
# Mc/sec: 593.47
//
Query:       EEA19544.1  [L=413]
Description: aminoalcoholphosphotransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.8e-17   63.8   0.2    1.8e-17   63.8   0.2    3.6  2  CDP-OH_P_transf  CDP-alcohol phosphatidyltransferase


Domain annotation for each model (and alignments):
>> CDP-OH_P_transf  CDP-alcohol phosphatidyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.8   0.2     1e-21   1.8e-17       1      66 []      46     121 ..      46     121 .. 0.96
   2 ?   -8.7  12.4         1   1.8e+04      25      25 ..     288     288 ..     125     384 .. 0.55

  Alignments for each domain:
  == domain 1  score: 63.8 bits;  conditional E-value: 1e-21
                      S-HHHHHHHHHHHHHHHHHGGGS-H.............HHHHHHHHHHHHHTTHHHHHHHHTT---H.HHHHHHHHHH CS
  CDP-OH_P_transf   1 nlPnaiTllrlllsvlailllltyyp...........lvlailllliasltDalDGklARrlnqvst.lGkllDslaD 66 
                      ++Pn+iTl+++ ++v+++l++l+++p           l +ai l+l++++ Da+DG++ARr++q s  lG+l+D+++D
       EEA19544.1  46 MAPNLITLTGFSFVVINFLTMLYFNPtldkdcpswvyLSWAIGLFLYQTF-DAVDGMQARRTRQ-SGpLGELFDHGVD 121
                      69*******************99999***********************9.*************.655********99 PP

  == domain 2  score: -8.7 bits;  conditional E-value: 1
                      H CS
  CDP-OH_P_transf  25 y 25 
                      +
       EEA19544.1 288 N 288
                      0 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (413 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       613  (0.0341904); expected 358.6 (0.02)
Passed bias filter:                      303  (0.0169); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.67u 0.35s 00:00:01.02 Elapsed: 00:00:00.58
# Mc/sec: 2134.94
//
Query:       EEA19545.1  [L=326]
Description: NIPSNAP family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.6e-40  135.3   5.8    1.4e-28   99.1   0.1    2.5  3  NIPSNAP   NIPSNAP
  ------ inclusion threshold ------
       0.14   12.3   0.9       0.25   11.5   0.9    1.4  1  MAS20     MAS20 protein import receptor
        1.4    9.8   4.1        9.3    7.2   4.1    2.1  1  TMA7      Translation machinery associated TMA7


Domain annotation for each model (and alignments):
>> NIPSNAP  NIPSNAP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.2       2.7   1.6e+04      75      84 ..      50      59 ..      44      73 .. 0.54
   2 !   39.4   0.1   9.3e-14   5.5e-10       3     100 ..     117     214 ..     113     216 .. 0.87
   3 !   99.1   0.1   2.3e-32   1.4e-28       1     102 []     227     324 ..     227     324 .. 0.99

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 2.7
                HHHHHHHHTT CS
     NIPSNAP 75 eaavekavdl 84
                ++++e+a++ 
  EEA19545.1 50 RQSLEEARKK 59
                4444444443 PP

  == domain 2  score: 39.4 bits;  conditional E-value: 9.3e-14
                 EEEEEE-TT-HHHHHHHHHHTHHHHH...HHHH--EEEEEEEEESBSSEEEEEEEES-HHHHHHHHHHHHH-HHHHHHHHHHHTT..EEEEEEEEEEE- CS
     NIPSNAP   3 lrtYtlkpgklaeflerfareiiaiq...ekhggeliGyfaseiGalnqvlhlwaydslaarearraalaadpeweaavekavdldliksmesrilkpt 98 
                 ++ +++kp k+ e++e + + + +++   e+ +++l+G + +++G++++++h+w y+ +  + +  +   ++ e++++ ++ ++l  iks e++++  +
  EEA19545.1 117 IVFHDVKPDKVDEYVELVGK-WYPRMasiEENKVNLVGSWRTQVGDNDTFVHIWEYQRYTGYHESLHNISQHAEFREFDKQLKSL--IKSKETSLMQEF 212
                 5679999*****99988776.333331115589****************************************************..*********988 PP

                 TT CS
     NIPSNAP  99 sf 100
                 sf
  EEA19545.1 213 SF 214
                 87 PP

  == domain 3  score: 99.1 bits;  conditional E-value: 2.3e-32
                 EEEEEEEE-TT-HHHHHHHHHHTHHHHHHHHH--EEEEEEEEESBSSEEEEEEEES-HHHHHHHHHHHHH-HHHHHHHHHHHTT..EEEEEEEEEEE-T CS
     NIPSNAP   1 yelrtYtlkpgklaeflerfareiiaiqekhggeliGyfaseiGalnqvlhlwaydslaarearraalaadpeweaavekavdldliksmesrilkpts 99 
                 +elr+Ytl+pg+l e+ ++++++ +a+ e   +e +G+++++iG+ln+v+hlw++++l++r+ rr++++   +w+++v+++v+l  i+sm+sril+p++
  EEA19545.1 227 FELRSYTLHPGNLLEWETHWRQGLQARRE--VMEGVGAWFVQIGDLNTVHHLWQFANLEERKIRREQSWGIEGWADTVHRTVPL--IQSMKSRILIPMP 321
                 59***************************..*****************************************************..************* PP

                 T-S CS
     NIPSNAP 100 fsp 102
                 +sp
  EEA19545.1 322 WSP 324
                 **8 PP

>> MAS20  MAS20 protein import receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.9   4.1e-05      0.25      22      83 ..      46     112 ..      42     122 .. 0.65

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 4.1e-05
       MAS20  22 dpefkkklrerrkkqakaakeeeeaekaekkk..kealeeakee...lptdaeevekfFleevqlGE 83 
                 ++ef+++l+e+rkk++++++++e+ + a+++   +  l++        ++  +++e+ F + +++G 
  EEA19545.1  46 QKEFRQSLEEARKKRQEQERDQEQLDDAAENGtrRGPLSSLIYGtreGQHFDKSIERSFSQVIARGK 112
                 689**********999888777776666555556333333333321122334777888888888776 PP

>> TMA7  Translation machinery associated TMA7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   4.1    0.0015       9.3      22      52 ..      54      84 ..      38      90 .. 0.81

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0015
        TMA7 22 eeDlafkqkqkeeekalkelkakaagkGplg 52
                ee  + +q q +++++l++++++++ +Gpl 
  EEA19545.1 54 EEARKKRQEQERDQEQLDDAAENGTRRGPLS 84
                56666778888899***************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (326 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1646  (0.0918066); expected 358.6 (0.02)
Passed bias filter:                      957  (0.0533772); expected 358.6 (0.02)
Passed Vit filter:                        75  (0.00418317); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.81u 0.37s 00:00:01.18 Elapsed: 00:00:00.60
# Mc/sec: 1644.56
//
Query:       EEA19546.1  [L=233]
Description: pyridoxamine phosphate oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.8e-12   45.1   0.0    2.2e-11   43.8   0.0    1.6  2  Putative_PNPOx  Pyridoxamine 5'-phosphate oxidase
  ------ inclusion threshold ------
      0.062   13.3   0.0       0.13   12.2   0.0    1.5  2  Pyridox_ox_2    Pyridoxamine 5'-phosphate oxidase


Domain annotation for each model (and alignments):
>> Putative_PNPOx  Pyridoxamine 5'-phosphate oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.8   0.0   2.4e-15   2.2e-11       3      69 ..      28      98 ..      26     107 .. 0.93
   2 ?   -3.3   0.0       1.2   1.1e+04      74      84 ..     140     150 ..     127     152 .. 0.73

  Alignments for each domain:
  == domain 1  score: 43.8 bits;  conditional E-value: 2.4e-15
                    HHHHHHHHHSSEEEEEEEETTSEEEEEEEEEEEETTT.....TEEEEEEETTSHHHHHHHHH-EEEEEEEET CS
  Putative_PNPOx  3 eelreflaeskavvlATvdedGrPnvspvllkagdgr.....dgivfatnadsrklrnleenprvallfldd 69
                    +e+++ l++s++ +lAT     +P+vs++++ ++  +      +i++ tn  s+k+ nl +nprv+ll++d+
      EEA19546.1 28 PEVVACLKNSRYLHLATS-DGLTPHVSLMSYTYLSSTpfdayPVIIMTTNPSSKKTLNLSANPRVSLLVHDW 98
                    7899*************9.5667*****************999***************************98 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 1.2
                     EEEEEEEEEEE CS
  Putative_PNPOx  74 gvrieGtaelv 84 
                     + +i Gta+++
      EEA19546.1 140 STTITGTARFL 150
                     45788888876 PP

>> Pyridox_ox_2  Pyridoxamine 5'-phosphate oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   1.5e-05      0.13       4      64 ..      29      97 ..      27     109 .. 0.85
   2 ?   -3.1   0.0      0.77   6.9e+03      81      96 ..     140     155 ..     132     168 .. 0.64

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 1.5e-05
                  HHHHHHHC-SEEEEEEEETTEEEEEEEEEEEETTE.......EEEEEETTSHCCHCCCT--.ECEEEEE CS
  Pyridox_ox_2  4 eilalLdegevgrlafvddgepvilPvnyvvdgds.......lyfhgakgsrlaaalrgap.vcvvvte 64
                  e+ a L+++++++la++d+  p++  ++y +   +       +++ + ++s+++  l+++p v+  v++
    EEA19546.1 29 EVVACLKNSRYLHLATSDGLTPHVSLMSYTYLSSTpfdaypvIIMTTNPSSKKTLNLSANPrVSLLVHD 97
                  78999*************999***********8888888996666688899999999977889999987 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 0.77
                   EEEEEEEEEEE--HHH CS
  Pyridox_ox_2  81 SVvvrGraeevtdeee 96 
                   S +++G+a+ ++   e
    EEA19546.1 140 STTITGTARFLEVGSE 155
                   5678888876543322 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (233 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       291  (0.0162307); expected 358.6 (0.02)
Passed bias filter:                      259  (0.0144459); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.35s 00:00:00.95 Elapsed: 00:00:00.57
# Mc/sec: 1233.92
//
Query:       EEA19547.1  [L=302]
Description: Lipoyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.8e-05   23.6   0.0    9.4e-05   22.3   0.0    1.6  2  BPL_LplA_LipB  Biotin/lipoate A/B protein ligase family


Domain annotation for each model (and alignments):
>> BPL_LplA_LipB  Biotin/lipoate A/B protein ligase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0      0.32   5.7e+03      74     105 ..      30      64 ..      18      65 .. 0.57
   2 !   22.3   0.0   5.2e-09   9.4e-05      33     127 ..     119     217 ..     109     219 .. 0.74

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 0.32
                    HHHHHH............HHTT-TTEEEETTTEEEETT CS
  BPL_LplA_LipB  74 avlealg.yrd.....skpgiegipvfikwpnDlyvng 105
                    a+ +a+  + +     + p +++i +f  +pn +y +g
     EEA19547.1  30 AYKKAVSsS-SpssisQLPPDPTIITF--TPNPVYTTG 64 
                    444444331.12323366666666666..888888776 PP

  == domain 2  score: 22.3 bits;  conditional E-value: 5.2e-09
                    SS-B-B--B-TTSEEEEEEEEESS...-CCGTHHHHHHHHHHHHHHH.........HHTT-TTEEEETTTEEEE..........TTEEEEEEEEEE CS
  BPL_LplA_LipB  33 tgGrnvwhspkgeltyslllspeqktfqnrvlelyvsllvlavlealg.y..rdskpgiegipvfikwpnDlyv..........ngrKlaGiavts 115
                    +gG+ ++h+p++ ++y++l++ +         ++++sll+ +v++ l  y     +++++g++v+  +                + rK+++++v+ 
     EEA19547.1 119 RGGQTTYHGPGQLVAYTILDLRRLG----LSPRCHISLLEKSVIDLLRkYglEGFTTQDPGVWVNPVT-----SttgatgngneEARKITAVGVHL 205
                    79*******************8873....344666666666666666332322267788888888333.....35556699999************ PP

                    EETTS-EEEEEE CS
  BPL_LplA_LipB 116 trgktlhhivig 127
                    +r   ++++ ++
     EEA19547.1 206 RRHISSFGVGLN 217
                    *97777666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (302 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       369  (0.0205812); expected 358.6 (0.02)
Passed bias filter:                      330  (0.0184059); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.31s 00:00:00.96 Elapsed: 00:00:00.55
# Mc/sec: 1651.27
//
Query:       EEA19548.1  [L=196]
Description: Rho GTPase Rho3 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    4.4e-52  175.9   0.0    5.1e-52  175.7   0.0    1.0  1  Ras        Ras family
    1.2e-20   73.9   0.0    2.3e-20   73.0   0.0    1.4  2  Roc        Ras of Complex, Roc, domain of DAPkinase
    1.2e-09   37.8   0.0    1.5e-09   37.5   0.0    1.0  1  Arf        ADP-ribosylation factor family
     0.0013   18.2   0.0     0.0016   17.9   0.0    1.2  1  Gtr1_RagA  Gtr1/RagA G protein conserved region
  ------ inclusion threshold ------
      0.092   11.9   0.0       0.13   11.4   0.0    1.4  1  G-alpha    G-protein alpha subunit
       0.11   12.0   0.0       0.17   11.3   0.0    1.3  1  SRPRB      Signal recognition particle receptor beta subunit
       0.19   11.8   0.0       0.28   11.3   0.0    1.4  1  MMR_HSR1   50S ribosome-binding GTPase


Domain annotation for each model (and alignments):
>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  175.7   0.0     2e-55   5.1e-52       1     160 [.      13     179 ..      13     181 .. 0.98

  Alignments for each domain:
  == domain 1  score: 175.7 bits;  conditional E-value: 2e-55
                 EEEEEESTTSSHHHHHHHHHHSSCSSSCTTTSSEEEEEEEEEETTEEEEEEEEEETTSGGGHHHHHHHHTTESEEEEEEETTBHHHHHTHH.HHHHHHH CS
         Ras   1 KlvlvGdsavGKtslllrfvkdkFkeeyesTigvdfytkeievdgkevkleiwDTAGqeefkslrelyyrdaegillvyditsresfenvk.kwveeik 98 
                 K+vl+Gd+a+GKts l+ f+++ F++ ye+T+ +++y+++i vd+++++l++wDTAGqeef++lr l+y+d+++i+l++++++r+sfenv+ kw+ ei+
  EEA19548.1  13 KMVLLGDGACGKTSALNVFTRGFFPTVYEPTV-FENYVHDIFVDNTHMELSLWDTAGQEEFDRLRALSYEDTHVIMLCFSVDNRDSFENVStKWMAEIH 110
                 89******************************.*********************************************************99******* PP

                 HHSTTTSEEEEEEETTTGGG.......G-SS-HHHHHHHHHHHT.SEEEEEBTTTTCTHHHHHHHHHHHH CS
         Ras  99 rvaeenvpivLvGnKvDlee.......kravsteegeelakelg.lkfletSAktnenveeafeellrei 160
                 + ++  v++vL + K+Dl++         av+++eg + ake+g +k+le+SA +n +++e+f+e+++ +
  EEA19548.1 111 ENCP-GVKMVLTALKCDLRKdeeqnenPDAVTFDEGLAKAKEVGaVKYLECSAVQNRGIRETFYEAAKVA 179
                 ****.7*************99999998899***********************************99876 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.0   0.0   8.8e-24   2.3e-20       1     119 [.      13     126 ..      13     127 .. 0.88
   2 ?   -3.3   0.0       3.9     1e+04      72      86 ..     168     182 ..     164     190 .. 0.70

  Alignments for each domain:
  == domain 1  score: 73.0 bits;  conditional E-value: 8.8e-24
                 EEEEESSTTSSHHHHHHCHCT-CCC-EEETTTTEEEEEEECGGSGGCTTBTTTTCEEEEEEEE-SGGCTTTT-HHHHCTSCEEEEEEE...GHHHHCH. CS
         Roc   1 KvvlvGdsgvGKtsllkrfvedkfsekekstigvdfltkevtkikgvendkkvkkvklniWDtaGqerfrslhplylreaalailvyd...srssenl. 95 
                 K+vl+Gd++ GKts l+ f+++ f + +++t+  ++++  +     v+n    ++++l++WDtaGqe+f+ l+ l +++ ++++l++    ++s+en+ 
  EEA19548.1  13 KMVLLGDGACGKTSALNVFTRGFFPTVYEPTVFENYVHDIF-----VDN----THMELSLWDTAGQEEFDRLRALSYEDTHVIMLCFSvdnRDSFENVs 102
                 89******************************999987654.....233....4789****************************98654344678874 PP

                 HHHHHHHHHHCSSS-EEEEEE-TT CS
         Roc  96 keWlkelkkvagkspvilvgnkiD 119
                  +W+ e++++++  +++l + k+D
  EEA19548.1 103 TKWMAEIHENCPGVKMVLTALKCD 126
                 68*******************999 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 3.9
                 T-HHHHCTSCEEEEE CS
         Roc  72 lhplylreaalailv 86 
                 +++ ++++a++a+ v
  EEA19548.1 168 IRETFYEAAKVALEV 182
                 677888888888755 PP

>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.5   0.0     6e-13   1.5e-09      14     168 ..      11     172 ..       3     178 .. 0.84

  Alignments for each domain:
  == domain 1  score: 37.5 bits;  conditional E-value: 6e-13
                 EEEEEEEESTTSSHHHHHHHHHHSSCEE.CSSSSSEE.EEEEEE..TTEEEEEEEE-SSGGGGGGGGGGCTTESEEEEEEETT-CTTHHHHHHHHHHHC CS
         Arf  14 elrilllGLDnaGKtTilkklkleelvt.tvPTigfn.veelei..knlkftvwDvGGqeklRplWknYfektdavifvvDsadreRleeakeeLkall 108
                 + +++llG  + GKt  l+ ++ + + t   PT+  n v+++ +   ++++++wD  Gqe+  +l    +e+t++++ +  + +r+ +e+ +++  a +
  EEA19548.1  11 QRKMVLLGDGACGKTSALNVFTRGFFPTvYEPTVFENyVHDIFVdnTHMELSLWDTAGQEEFDRLRALSYEDTHVIMLCFSVDNRDSFENVSTKWMAEI 109
                 5689****99***************998578**9877478877622568899*************************999999999***9998866655 PP

                 TSGCCTTSEEEEEEE-TTSTTSS-HHHHHHHTTGGG....SSSSSSEEEEEEBTTTTBTHHHHH CS
         Arf 109 eeeelkevallvlaNKqDlpealseeelrellglee....lkgkrkleiqkcsavkgeglkegl 168
                  +e+   v++++ a K Dl+++ +++e  ++++ +e     k    ++  +csav+++g+ e++
  EEA19548.1 110 -HENCPGVKMVLTALKCDLRKDEEQNENPDAVTFDEglakAKEVGAVKYLECSAVQNRGIRETF 172
                 .456789***************99999888888777643245566778889*********9987 PP

>> Gtr1_RagA  Gtr1/RagA G protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.0   6.1e-07    0.0016       1     131 [.      13     135 ..      13     175 .. 0.76

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 6.1e-07
   Gtr1_RagA   1 kvLLmGksgsGKtsmrsiiFdnylardtlrlgatidveksevrflgnltlnlwDcgGqeafveeylssqkeeifrnvgvliyVfDvesreleedletlk 99 
                 k++L+G +  GKts  ++    + ++   + ++  +  ++ +  + +++l+lwD  Gqe+f        ++  +++  v++  f v++r+  e++   +
  EEA19548.1  13 KMVLLGDGACGKTSALNVFTRGFFPTV-YEPTVFENYVHDIFVDNTHMELSLWDTAGQEEFDRL-----RALSYEDTHVIMLCFSVDNRDSFENV--ST 103
                 789***********9998888888864.44444455666666678899**********998655.....45555566666666666655533333..35 PP

   Gtr1_RagA 100 eilealrqyspeakvfvlihKmDliqederee 131
                 + + +++++ p +k+     K+Dl +++e++e
  EEA19548.1 104 KWMAEIHENCPGVKMVLTALKCDLRKDEEQNE 135
                 7899999*******999999999999887766 PP

>> G-alpha  G-protein alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   5.2e-05      0.13      24      81 ..      12      67 ..       4     185 .. 0.68

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 5.2e-05
                EEEEEEESTTSSHHHHHHHHHHHCS----HHHHHCCHHHHHHHHHHHHHHHHHHHHHT CS
     G-alpha 24 vkllllGqseSGKsTilkqlkllykkgfseeelatwraviqlnivrsiktilealesl 81
                 k++llG + +GK++ l+ + + + +++ e     + ++++  +v++ ++ l   ++ 
  EEA19548.1 12 RKMVLLGDGACGKTSALNVFTRGFFPTVYEP--TVFENYVHDIFVDNTHMELSLWDTA 67
                389******************9998888877..4466677777776666666555554 PP

>> SRPRB  Signal recognition particle receptor beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   6.7e-05      0.17       3      84 ..      11      93 ..       9     111 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 6.7e-05
                --EEEEE-STTSSHHHHHHHHHHSS---B---S..S-EEETTG...GGTT-SEEEETT-GCC.SHHHHHHHHHHGGEEEEEEEEE CS
       SRPRB  3 kpavllvGlsdsGKTslftrLttdsvkktvtSq..essaalkvksekgskltliDfPGhekl.rqklleklkaksslkglvfvvD 84
                +++++l+G   +GKTs ++  t + + + +     e+ + + + ++ + +l l D  G+e++ r + l +  + +++  l f vD
  EEA19548.1 11 QRKMVLLGDGACGKTSALNVFTRGFFPTVYEPTvfENYVHDIFVDNTHMELSLWDTAGQEEFdRLRALSY--EDTHVIMLCFSVD 93
                78899******************95444333222388888888999999*********999833333333..5555777777777 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00011      0.28       2      86 ..      14      93 ..      13     140 .. 0.67

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00011
                EEEEESTTSSHHHHHHHHHTSTEEESSSTTSSSSEEEEEEEETT.EEEEEEECGGCSSHHHHHHHHHHHHHHHHCTSEEEEEEETT CS
    MMR_HSR1  2 vaivGrpNvGKStLinaltgekaivsdkpgtTrdinegrvklkg.keielvDtpGliegaseekglgkaflaleeadlillvvdas 86
                ++++G    GK++ +n  t+    +  +p +  + ++  +  +   e+ l+Dt+G  e    e +  +a+   e++++i+l++++ 
  EEA19548.1 14 MVLLGDGACGKTSALNVFTRGFFPTVYEPTVFENYVHDIFVDNThMELSLWDTAG-QE----EFDRLRALS-YEDTHVIMLCFSVD 93
                678999999***********988888888777777776665333489********.44....333333333.45555655555433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (196 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       481  (0.026828); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.63u 0.36s 00:00:00.99 Elapsed: 00:00:00.58
# Mc/sec: 1016.15
//
Query:       EEA19549.1  [L=333]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.6e-14   52.5   0.0    7.7e-14   52.0   0.0    1.2  1  Abhydrolase_3    alpha/beta hydrolase fold
    1.4e-06   27.9   0.0     0.0028   17.2   0.0    2.2  2  Peptidase_S9     Prolyl oligopeptidase family
    0.00013   21.3   0.0    0.00056   19.2   0.0    1.8  1  Hydrolase_4      Serine aminopeptidase, S33
    0.00072   18.5   0.0     0.0011   18.0   0.0    1.2  1  Chlorophyllase2  Chlorophyllase enzyme
     0.0016   17.2   0.0       0.41    9.3   0.0    2.2  2  AXE1             Acetyl xylan esterase (AXE1)
     0.0042   16.0   0.0      0.011   14.6   0.0    1.6  2  COesterase       Carboxylesterase family
  ------ inclusion threshold ------
      0.098   12.3   0.0       0.13   11.9   0.0    1.4  1  Abhydrolase_1    alpha/beta hydrolase fold
        0.2   11.3   0.0       0.44   10.1   0.0    1.5  2  Esterase         Putative esterase


Domain annotation for each model (and alignments):
>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.0   0.0   3.4e-17   7.7e-14       4     110 ..      54     169 ..      51     212 .. 0.85

  Alignments for each domain:
  == domain 1  score: 52.0 bits;  conditional E-value: 3.4e-17
                    E--STTTS--TTTT...HHHHHHHHHHHTSEEEEEE---TTTS-TTHHHHHHHHHHHHHHHTH.........H.HHTETTCEEEEEEETHHHHHHH CS
  Abhydrolase_3   4 fHGGGfvlgsldth...dalcrelakelgavvvsvdYrlAPehpfPaavedalaalrwlaeqa.........w.elgadpsrivlaGdSaGGnlaa 86 
                    fHGGG v g++  +    a++ ela+  +av+vsv+Yr  Pe      ++d+ + + wl++++           + ++d +ri+ aGdSaGG l+ 
     EEA19549.1  54 FHGGGLVRGESLYEdwfPAWLLELAETHNAVIVSVNYRFLPEVTGLDILDDVDDFWTWLHSKDlatilhtqkDvAVELDLDRIITAGDSAGGLLSI 149
                    9******8887555355899**************************************************9945999******************* PP

                    HHHHHHHHTT---EEEEEEESE-S CS
  Abhydrolase_3  87 avalrardegepkvagqvliyPvt 110
                    +++l   de    +++    yP++
     EEA19549.1 150 YLVLSHPDE----IRAGTAAYPAL 169
                    ***999987....88888888854 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   1.2e-06    0.0028      45     101 ..     114     171 ..      70     177 .. 0.77
   2 !    8.6   0.0   0.00051       1.1     128     195 ..     245     316 ..     224     327 .. 0.74

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 1.2e-06
                   HHHHHHHHHHHHHTT.S--GGGEEEEEETHHHHHHHHHHHH-GGG-SEEEEESE---C CS
  Peptidase_S9  45 fdDfiaaaealakeg.yvdserlaitGgSyGGyltgaalnqrpdlFkaavaevpvvdv 101
                    +D+ +++ +  +     d +r++  G S+GG+l+  ++ ++pd  +a+ a++p + +
    EEA19549.1 114 SKDLATILHTQKDVAvELDLDRIITAGDSAGGLLSIYLVLSHPDEIRAGTAAYPALGW 171
                   56666666666666667899*********************************99877 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.00051
                   HHHHHHH-CGGG-----EEEEEEETT-SSS-THHHHHHHHHHH.....--S-SEEEEEETTS-SSTTSSHHHH CS
  Peptidase_S9 128 ykelspyspldnvkaypplLlihGlaDdrvppaealklvaaLq.....kkgknvlllifpdegHgvgkprakv 195
                   y +ls ++++d+      l ++hG  Dd v ++ ++++v++ q     ++g +  +l      Hg+ ++ + +
    EEA19549.1 245 Y-QLSRLEKADARLPRGGLVILHGVDDDIVLVKASERFVEKAQdalkgRQGGDKIILALRPGPHGFDTDASIK 316
                   3.666666666655788899********************999888887777755555555567777666655 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   0.0   2.5e-07   0.00056      60     219 ..     115     287 ..     104     293 .. 0.66

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 2.5e-07
  Hydrolase_4  60 dDlaafvekvkeehpel...plfllGhSmGGliallyllrypdkvaglilsaPalkikakl....k.appllklllkllgkllpklqv.......... 139
                  +Dla+++++ k+   el   +++  G S GGl+++ ++l +pd++++   + Pal+++++     k    + ++ + ++ + +               
   EEA19549.1 115 KDLATILHTQKDVAVELdldRIITAGDSAGGLLSIYLVLSHPDEIRAGTAAYPALGWDNPPllptKrSVFIPEVPASFIDEYV----Adikpgqvsss 208
                  688888877765555555678999**********************9999999999986532322112222222333333333....25555888854 PP

  Hydrolase_4 140 ....snnlkadslsrdpevvaayeadplvhgkitvrlllelldamkrleeraakit.lPllllhGeaDkvvdpeasrelyerlgs 219
                      ++    + +s +++  + y +d+        +  ++ l  ++rle+ +a++    l +lhG +D +v  +as++++e+++ 
   EEA19549.1 209 dldlQRLQIGAAISANQAGFKFYIRDS------ESSPTRDRLYQLSRLEKADARLPrGGLVILHGVDDDIVLVKASERFVEKAQD 287
                  445444444455555555555555554......444444444445555555555533569*********************9986 PP

>> Chlorophyllase2  Chlorophyllase enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   4.8e-07    0.0011      13     113 ..      44     157 ..      34     193 .. 0.75

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 4.8e-07
  Chlorophyllase2  13 eageYpvllflhGyl......llnslYsq.lLkhiashgfivvapqlykvaeada.keiksaakvlnWlakg.Lesvlp....eevepdlskla 93 
                       ag+ pv+  +hG        l+++++   lL+    h  ++v+++   + e  + + ++ +    +Wl+++ L+++l       ve dl+++ 
       EEA19549.1  44 PAGKAPVIARFHGGGlvrgesLYEDWFPAwLLELAETHNAVIVSVNYRFLPEVTGlDILDDVDDFWTWLHSKdLATILHtqkdVAVELDLDRII 137
                      5788888887776543334445555555535666668********977766655545567888999***9988*****97766678999***** PP

  Chlorophyllase2  94 lsgHSrGgktafalalgkak 113
                       +g S+Gg  ++ l+l + +
       EEA19549.1 138 TAGDSAGGLLSIYLVLSHPD 157
                      ****************9987 PP

>> AXE1  Acetyl xylan esterase (AXE1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.0   0.00018      0.41      58      95 ..      22      60 ..      12      71 .. 0.83
   2 !    5.8   0.0    0.0021       4.8     170     208 ..     130     169 ..     104     171 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00018
                EEEEEEGGGEEEEEEEEEES..SSSSEEEEEEEE-TT-- CS
        AXE1 58 dltfegvrgarikaklvlPke.keeklPavvefhGYegs 95
                +  ++ v g++i+a l+ Pk+  ++k P++ +fhG    
  EEA19549.1 22 QANYKVVDGHEIRADLIIPKSlPAGKAPVIARFHGGGLV 60
                567999*************96369**********97655 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0021
                 TEEEEEEEEEEETHHHHHHHH.HHHH-SS-SEEEEES-SS CS
        AXE1 170 evDeeRvavlGasqGGalala.vaalekrikavvadyPfL 208
                 e D +R+  +G+s GG l++  v +  ++i+a +a yP L
  EEA19549.1 130 ELDLDRIITAGDSAGGLLSIYlVLSHPDEIRAGTAAYPAL 169
                 5799***************962456667889999999866 PP

>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   5.1e-06     0.011     102     143 ..      45      91 ..      35      93 .. 0.77
   2 ?   -2.5   0.0      0.79   1.8e+03     184     206 ..     133     155 ..     132     158 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 5.1e-06
                 TSSEEEEEEE--STTTS-BG..CG...S-THHHHHHHTSEEEEE--- CS
  COesterase 102 kkklPVlVwihGggfqtgsa..se...ydgsaLaaegnvivVtinYR 143
                   k PV+  +hGgg++ g +  ++   +   +La++ n ++V++nYR
  EEA19549.1  45 AGKAPVIARFHGGGLVRGESlyEDwfpAWLLELAETHNAVIVSVNYR 91 
                 3455************999955335445567899999********** PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.79
                 EEEEEEEEETHHHHHHHHHHHSG CS
  COesterase 184 pervtlfGesAGaasvsllllsp 206
                  +r+  +G+sAG+ +  +l+ls+
  EEA19549.1 133 LDRIITAGDSAGGLLSIYLVLSH 155
                 5788999******9988888885 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   5.7e-05      0.13      69     135 ..     130     200 ..      60     287 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 5.7e-05
                    HCTTSSEEEEEETHHHHHHHHHHHHHGGGEEEEEEESE....CSSCCHHHHHHHHHHHHHHCHHCHHHHHH CS
  Abhydrolase_1  69 algddkltlvGhSmGGmialayaaeyperVkalvllga....idpaaslieaqrqqaksfpdffdgyaadc 135
                     l++d+++  G S GG+++ ++ + +p+ ++a ++  +     +p+  + +   ++ + +  f d y+ad 
     EEA19549.1 130 ELDLDRIITAGDSAGGLLSIYLVLSHPDEIRAGTAAYPalgwDNPPLLPTKRSVFIPEVPASFIDEYVADI 200
                    68999****************************99999887666666666666666666666666666665 PP

>> Esterase  Putative esterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       1.4   3.1e+03       6      35 ..      31      58 ..      30      88 .. 0.71
   2 ?   10.1   0.0    0.0002      0.44      98     139 ..     113     158 ..     102     203 .. 0.80

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 1.4
                EEEEEEEEE.CC.GGTTTEEEEEEE--TTH CS
    Esterase  6 reikvqvyLPedyspgrkypvvylldGltg 35
                +ei+  +  P++  p++k pv+  ++G  g
  EEA19549.1 31 HEIRADLIIPKS-LPAGKAPVIARFHGG-G 58
                567777788888.899999999999993.3 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.0002
                 HHTHHHHHHHHHCSEECCC....EEEEEETHHHHHHHHHHHCSTTT CS
    Esterase  98 ltqeLlplldanfrtapdg....ravaGqSmGGlgALilalkhpdr 139
                 +++ L+ +l +++++a +        aG+S GGl +++l l hpd+
  EEA19549.1 113 HSKDLATILHTQKDVAVELdldrIITAGDSAGGLLSIYLVLSHPDE 158
                 456677777777777777777734447*****************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (333 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       383  (0.021362); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2364.05
//
Query:       EEA19550.1  [L=560]
Description: siroheme synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.4e-49  167.0   0.0    2.4e-46  158.3   0.0    2.2  2  TP_methylase    Tetrapyrrole (Corrin/Porphyrin) Methylases
    1.9e-18   66.8   0.0    3.8e-18   65.8   0.0    1.5  1  NAD_binding_7   Putative NAD(P)-binding
    2.3e-14   52.8   0.7    7.4e-09   35.1   0.1    2.7  2  Sirohm_synth_C  Sirohaem biosynthesis protein C-terminal
    1.3e-07   31.0   0.1    2.7e-07   29.9   0.1    1.6  1  Sirohm_synth_M  Sirohaem biosynthesis protein central
  ------ inclusion threshold ------
      0.093   13.0   0.0       0.35   11.2   0.0    2.0  1  preATP-grasp_3  pre ATP-grasp 3 domain


Domain annotation for each model (and alignments):
>> TP_methylase  Tetrapyrrole (Corrin/Porphyrin) Methylases
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.8   0.0    0.0017       5.9      61     133 ..      71     141 ..      33     205 .. 0.81
   2 !  158.3   0.0   6.8e-50   2.4e-46       1     212 [.     283     501 ..     283     502 .. 0.91

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0017
  TP_methylase  61 leeayeeiaeal.aealragkdVvllvsGDPlvygtgselvealrareagieveviPGvsslqaaaarlgiplt 133
                   ++e ++e  ++l +e+++   d+v+++sGD  ++++ s l+++ r     ++v   P  +s++++ ++++ pl+
    EEA19550.1  71 QREFQDEDLKTLgREEVDHVVDAVFVTSGDHDLSTRISQLCKRMRI---PVNVTDAPDLCSFTLLSTYSDGPLH 141
                   4566999999999****************************88887...4677777888888888888777776 PP

  == domain 2  score: 158.3 bits;  conditional E-value: 6.8e-50
  TP_methylase   1 klylVGvGpGdpellTvrAlralktadvvlgddsraleilldllaeel.eleapmgkekepleeayeeiaealaealragkdVvllvsGDPlvygtg 96 
                   k++l+G GpG+p+ lT ++++a+k+ad++l+d+ ++++ +l+l+++++ ++ a++++   ++++a+ee  ++  +  r+gk V++l++GDP++yg+g
    EEA19550.1 283 KIVLAGSGPGHPDMLTRATYNAIKNADIILADK-LVPAPVLELIPRRTeVHIARKFPG--NADQAQEEFLQMGLKSIREGKYVLRLKQGDPYLYGRG 376
                   799***************************999.*************99999999999..9************************************ PP

  TP_methylase  97 selvealrareagieveviPGvsslqaaaarlgiplteggevlsvl......lpglakeeereleallangdtlvllkaprklaelaelL....... 180
                   +e++ ++r+  +g+   v+PG++s+ +a+ +++ip t++g++ +vl      ++g a++e+  +      ++t+v+l+a+++l++l+  L       
    EEA19550.1 377 GEEYCFFRE--KGYIPTVLPGITSALSAPLFADIPATHRGVADQVLvctgtgRKG-AAPEPPTY----VSTQTVVFLMALHRLSDLVVSLtstspse 466
                   *********..9**********************************987763333.44555555....336*************************9 PP

  TP_methylase 181 ...kea.lyddttpvavveragtedervvrgtleel 212
                      k+  +++  tp+avvera+++d+r++r+tle++
    EEA19550.1 467 easKRTlWPK-STPCAVVERASCPDQRIIRTTLEHV 501
                   9965555777.55*********************87 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.8   0.0   1.1e-21   3.8e-18       2     102 ..      13     131 ..      12     133 .. 0.84

  Alignments for each domain:
  == domain 1  score: 65.8 bits;  conditional E-value: 1.1e-21
  NAD_binding_7   2 fldlkgkkvlvvGgGevAarkvrklleagakvtvvapev..keele.........elvklaeeele.kdleg.........adlviaatddrelne 76 
                    ++  + +  l++G +++Aa ++ k l++ga+ +v+ape+      +         e+v+++++e++ +dl+          +d v+++  d++l++
     EEA19550.1  13 AISATSQIHLIIGTNPLAAARCTKSLQSGARPIVIAPETsdV---HfslkdciekEQVQWIQREFQdEDLKTlgreevdhvVDAVFVTSGDHDLST 105
                    566677788*****************************6550...244555666699********636766555666666789************* PP

  NAD_binding_7  77 riaeaakarrilvnvadkpelcdfif 102
                    ri +++k+ ri+vnv+d p+lc+f++
     EEA19550.1 106 RISQLCKRMRIPVNVTDAPDLCSFTL 131
                    ************************85 PP

>> Sirohm_synth_C  Sirohaem biosynthesis protein C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   3.1e-06     0.011       1      28 [.     166     193 ..     166     198 .. 0.85
   2 !   35.1   0.1   2.1e-12   7.4e-09      21      66 ..     216     263 ..     213     265 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 3.1e-06
  Sirohm_synth_C   1 PdnlgaAiekvgkLRkkLReiapdqeeg 28 
                     P nlg+Ai+++g+LR++L e   +q+++
      EEA19550.1 166 PANLGQAIDRLGTLRRRLWEEDHQQQQS 193
                     89****************9987777554 PP

  == domain 2  score: 35.1 bits;  conditional E-value: 2.1e-12
  Sirohm_synth_C  21 iapdq..eegpkRMkWmskvcdswsleelaeldeedmekLlemyekgk 66 
                     i+pd+  +++ +RM+W+ ++c+ w l++la+++++d++++l+ y+ ++
      EEA19550.1 216 ITPDDeqTTKTRRMRWLAQICEYWPLQRLASISDSDIDSILTSYSRDR 263
                     566663245556*******************************99875 PP

>> Sirohm_synth_M  Sirohaem biosynthesis protein central
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.9   0.1   7.6e-11   2.7e-07       1      27 [.     137     163 ..     137     164 .. 0.95

  Alignments for each domain:
  == domain 1  score: 29.9 bits;  conditional E-value: 7.6e-11
  Sirohm_synth_M   1 rGpLQIaiSTnGksPrLAaliRreier 27 
                     +GpL I i+T G +++LA+++Rrei +
      EEA19550.1 137 DGPLHIGITTSGRGCKLASRLRREISS 163
                     8************************76 PP

>> preATP-grasp_3  pre ATP-grasp 3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   9.7e-05      0.35      46      70 ..      46      70 ..      43      71 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 9.7e-05
  preATP-grasp_3 46 vIAPEtdgiLarltrlveaagkrlL 70
                    vIAPEt +++ +l  ++e+++  ++
      EEA19550.1 46 VIAPETSDVHFSLKDCIEKEQVQWI 70
                    9******************998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (560 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       692  (0.0385967); expected 358.6 (0.02)
Passed bias filter:                      528  (0.0294495); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.61u 0.29s 00:00:00.89 Elapsed: 00:00:00.46
# Mc/sec: 3690.63
//
Query:       EEA19551.1  [L=1458]
Description: multidrug resistance-associated protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      1e-45  155.6   0.1    3.1e-29  102.2   0.0    2.4  2  ABC_tran      ABC transporter
    1.1e-27   97.3  15.4    1.1e-27   97.3  15.4    2.8  2  ABC_membrane  ABC transporter transmembrane region
      1e-14   54.5   4.4    4.6e-06   26.2   0.1    4.2  2  SMC_N         RecF/RecN/SMC N terminal domain
    8.5e-10   38.9   1.4      0.042   13.7   0.1    4.3  4  AAA_21        AAA domain, putative AbiEii toxin, Type IV TA s
    8.6e-09   35.5   0.6     0.0028   17.6   0.0    3.3  3  RsgA_GTPase   RsgA GTPase
    4.5e-08   33.8   1.1     0.0016   19.0   0.6    2.4  2  AAA_23        AAA domain
    3.9e-07   29.7   1.5      0.012   15.4   0.2    2.5  2  AAA_29        P-loop containing region of AAA domain
    6.9e-07   29.6   0.1      0.029   14.6   0.0    2.9  2  AAA_22        AAA domain
    7.9e-07   29.6   0.0      0.014   15.8   0.0    2.8  2  AAA_16        AAA ATPase domain
      1e-06   28.8   0.5       0.01   15.5   0.0    2.2  2  AAA_15        AAA ATPase domain
    1.2e-05   25.8   0.0      0.027   14.9   0.0    3.2  2  AAA           ATPase family associated with various cellular 
      5e-05   22.5   0.1      0.037   13.1   0.0    2.3  2  T2SSE         Type II/IV secretion system protein
      9e-05   22.1   0.8        0.2   11.2   0.4    2.8  2  cobW          CobW/HypB/UreG, nucleotide-binding domain
    9.1e-05   22.5   0.2       0.12   12.4   0.0    3.4  2  AAA_5         AAA domain (dynein-related subfamily)
     0.0001   22.4   0.0     0.0084   16.2   0.0    2.3  2  Dynamin_N     Dynamin family
    0.00067   19.7   0.2        1.1    9.3   0.2    2.7  2  MMR_HSR1      50S ribosome-binding GTPase
    0.00071   19.8   0.0       0.28   11.4   0.0    2.6  2  AAA_33        AAA domain
    0.00072   19.3   0.7       0.13   11.9   0.0    3.3  3  IstB_IS21     IstB-like ATP binding protein
    0.00086   19.3   0.2        0.5   10.2   0.2    2.7  2  ATPase_2      ATPase domain predominantly from Archaea
     0.0012   18.8   0.1        2.4    8.1   0.0    2.5  2  NACHT         NACHT domain
     0.0015   18.1   0.0       0.38   10.3   0.0    3.1  3  AAA_25        AAA domain
     0.0027   17.2   0.1       0.23   10.9   0.0    2.4  2  AAA_7         P-loop containing dynein motor region
     0.0031   17.7   0.0        1.5    9.0   0.0    2.7  2  Roc           Ras of Complex, Roc, domain of DAPkinase
     0.0038   16.4   4.3        0.2   10.8   0.6    3.3  2  NB-ARC        NB-ARC domain
      0.007   16.2   0.1        1.5    8.5   0.0    2.3  2  AAA_11        AAA domain
  ------ inclusion threshold ------
      0.017   14.9   0.2        1.7    8.4   0.0    2.7  2  ATP_bind_1    Conserved hypothetical ATP binding protein
      0.018   14.8   0.2        8.6    6.0   0.0    2.6  2  AAA_30        AAA domain
       0.02   15.4   0.2        1.1    9.8   0.0    2.7  2  AAA_18        AAA domain
      0.023   15.1   0.1        1.7    9.1   0.0    2.8  2  RNA_helicase  RNA helicase
      0.025   14.6   0.0         21    5.1   0.0    3.4  3  AAA_14        AAA domain
      0.039   14.3   1.9        8.7    6.7   0.1    2.9  2  AAA_19        AAA domain
       0.04   13.3   0.8        1.2    8.5   0.1    2.2  2  FtsK_SpoIIIE  FtsK/SpoIIIE family
      0.042   13.9   0.0        3.3    7.7   0.0    2.4  2  TsaE          Threonylcarbamoyl adenosine biosynthesis protei
      0.043   13.3   0.1         15    4.9   0.0    2.7  3  PhoH          PhoH-like protein
      0.053   13.4   0.4        1.1    9.2   0.0    2.6  2  MobB          Molybdopterin guanine dinucleotide synthesis pr
      0.057   13.2   0.2        2.8    7.7   0.0    3.1  3  DEAD          DEAD/DEAH box helicase
      0.075   12.5   0.0        8.1    5.8   0.0    2.4  2  SRPRB         Signal recognition particle receptor beta subun
      0.097   12.0   0.1        2.1    7.7   0.0    2.2  2  Mg_chelatase  Magnesium chelatase, subunit ChlI
       0.11   11.3   0.1        1.6    7.3   0.0    2.1  2  RNA12         RNA12 protein
       0.11   12.0   0.2        5.4    6.5   0.0    2.8  2  GTP_EFTU      Elongation factor Tu GTP binding domain
       0.11   12.1   0.3       0.75    9.5   0.0    2.2  2  AAA_24        AAA domain
       0.12   11.2   1.0        1.3    7.7   0.1    2.2  2  Adeno_IVa2    Adenovirus IVa2 protein
       0.12   11.5   0.1       0.56    9.3   0.0    1.9  2  DUF815        Protein of unknown function (DUF815)
       0.21   11.8   0.3        3.2    8.0   0.0    2.5  2  AAA_28        AAA domain
       0.75    9.7   4.1         10    6.0   0.0    3.3  3  NTPase_1      NTPase
       0.97    8.2   2.6        7.3    5.3   0.4    2.9  4  ABC_ATPase    Predicted ATPase of the ABC class


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.1   0.0   4.9e-16   1.9e-13       2     135 ..     626     759 ..     625     761 .. 0.76
   2 !  102.2   0.0   8.1e-32   3.1e-29       1     137 []    1238    1384 ..    1238    1384 .. 0.91

  Alignments for each domain:
  == domain 1  score: 51.1 bits;  conditional E-value: 4.9e-16
                 EEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.........HHHTC....... CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.........xxxxx....... RF
    ABC_tran   2 knvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren.........esdee....... 84 
                 +n+ l++ +g ++ i+G+ G+GKS Ll+ ++g+++ + G+             ++   ++++++q+p + +++ ++ n         +   +       
  EEA19551.1 626 ENLRLDIGNG-ITIIIGPVGSGKSALLESIIGETHLKDGTT------------TKPLTRVAYCSQNPWIINNT-IKFNitngsehidQ---Kwydftiw 707
                 5666777666.6789************************98............67788899999998888888.66666777775441...33445555 PP

                 ...HHHHHHHSTTGGTTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEEST CS
                 ...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  85 ...iekalsklglkelkdtvvksspssLSgGqkqrvalarallkkpkllllDEp 135
                    +e+ l+++   +  +   +s++ sLSgGqkqrvalara+ ++ ++++lD+ 
  EEA19551.1 708 acaLEEDLKSIPGGD--QFQTGSNGVSLSGGQKQRVALARAVYSRLPIVILDDV 759
                 444555555555444..55566788***************************85 PP

  == domain 2  score: 102.2 bits;  conditional E-value: 8.1e-32
                  EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.......HHHTCHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxx RF
    ABC_tran    1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren.......esdeeiekals 90  
                  lkn+slk+++gekvai G++G+GK++L+++l+++ + ++G+i++d++dl+ +e   lr +i v+pqep++ p++ vr n        sde ie+al+
  EEA19551.1 1238 LKNLSLKINAGEKVAICGPSGSGKTSLVMALLQMINLQSGRIEIDSRDLSAIECADLRTRINVIPQEPFFMPGT-VRFNmdpsenkVSDETIEAALA 1333
                  79************************************************************************.9999999998888888****** PP

                  HSTTGG.......TTCBGESTTS....GGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                  xxxxxx.......xxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran   91 klglke.......lkdtvvkssp....ssLSgGqkqrvalarallkkpkllllDEpta 137 
                  k+gl +       l       ++    s  S G++q +alaral  k+++l+lDE t+
  EEA19551.1 1334 KVGLWKrisanggL-------EMalvmSDWSVGERQLLALARALTMKSSILVLDEVTS 1384
                  ****9955433332.......224566****************************985 PP

>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4  12.3       1.1   4.1e+02       9     274 .]     277     543 ..     270     543 .. 0.69
   2 !   97.3  15.4   2.9e-30   1.1e-27       7     269 ..     903    1165 ..     900    1170 .. 0.83

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 1.1
                   HHHHHHHHHHHHHHHHHHHHHHSSTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHHHH.SCHHHHHHHH CS
  ABC_membrane   9 ilagvlsplfplvlgrildtlldkgdpetealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsffdt.nsvGellsrl 104
                   ++++v  + +p++++  ++++ ++ ++    ++ y  +l+++++++ +  ++++ ++     rl + +r+ l+  i rq     ++ ++  e +++ 
    EEA19551.1 277 LCVTVFTFCQPFLINATVNFMATTTTTPE--TKSYGQALVGAYALVYLGLTISTAVYWRQTFRLATMIRAGLISMIYRQTSLLKSSsMRGNEAITLH 371
                   56678888899999999999998777777..899999999999999999999999998888888888999999888888444444467777888888 PP

                   HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHTTT CS
  ABC_membrane 105 tndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsav...iakilkklkkkeqkavakassvaeEslsgirtVkafgr 198
                    +dv+ + +++     ++  + ++++ + + +++l  +++ ++++ ++++i++ +    ++ ++  ++k   ++++k+ +v+  +l  ++ Vk +g 
    EEA19551.1 372 GTDVEVIVTSV----KVIHEAWVSLLEVGVALWLLERQIFAACVVPAIICIVCVIAagpLSTLSVGAQKAWVEQIEKRLAVTSTVLGDMKAVKMLGL 464
                   88999554444....4444444444444444444444444444443334444433301233344466777778999********************* PP

                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH....HHHHHHHHHHHHHHHHHHTTSSTHHHHHHHHHHHHHHHHHH CS
  ABC_membrane 199 eeyflekfekaleeakkagikkaianglligitql....lgllsyalalwfGttlvisgelsvgdlvvflslfailfgal 274
                    + + + +   ++ ++k + k  ++  l+ +i+++    ++++ +++ + +++   ++ +l  + +++ lsl++il+ +l
    EEA19551.1 465 TDLVFSIISALRKVELKTSTKLRKLILLQVSISNVpidlAPFATFVVYAIIAA-VKKDETLLASRAFTALSLISILTSPL 543
                   ***********999999998765554444444444333055555555545444.444669999999*********99886 PP

  == domain 2  score: 97.3 bits;  conditional E-value: 2.9e-30
                    HHHHHHHHHHHHHHHHHHHHHHHHSSTCCHH.HHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHHHHHHHHHCSTHHHHHHSCHHH CS
  ABC_membrane    7 lailagvlsplfplvlgrildtlldkgdpet.ealnvysllllllglaqfilallqsyll.nvtgerlskrlrrklfkkilrqpmsffdtnsvGe 99  
                    l i++ ++s +f+++   +l++ +d ++++   +l +y+ +++++++++f   +    ll  ++  ++ + ++++l+++ l +p sff ++++G+
    EEA19551.1  903 LFIFSILVSAFFSSFAILWLQWWSDANETQPnGRLGYYLGVYAAIFVLNFMGLVSACQLLfVNIINNTGSGMHSDLLRATLGAPFSFFLKTDTGT 997 
                    345555555555555555555555544444411255555555555555554444333333488999***************************** PP

                    HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHH CS
  ABC_membrane  100 llsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirtVk 194 
                     ++r++ d++ ++  l+   + f  +l++ + +l+++++ g +l++ + ++ + +++++ ++ +++++++  + +a ++++++++E++ gi tV+
    EEA19551.1  998 TTNRFSQDINLIDMDLPIASINFAANLSMSIFSLAILCIAGKYLAITVPFLGLAVFFLQLYYLRTSRQVRLLDIEAKSPLYTHFIETIGGIATVR 1092
                    *********************************************************************************************** PP

                    HTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSTHHHHHHHHHHHHH CS
  ABC_membrane  195 afgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttlvisgelsvgdlvvflslfai 269 
                    a+g+e++f+++ e++l++ +k  ++   ++ +l  +++l++ ++ ++   ++tt++++++ s+g++ v l l  +
    EEA19551.1 1093 AYGWESIFQDECEQKLNQSQKPFYMLMCIQIWLTLVLDLIVGIMAVIL--MATTTSLKDNFSPGSVGVGLNLVLL 1165
                    ***************************************997776666..6788888899999998887777654 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.2   0.1   1.2e-08   4.6e-06      18     211 ..     628     808 ..     624     811 .. 0.72
   2 !   16.0   0.9   1.6e-05    0.0061      27     209 ..    1251    1424 ..    1239    1431 .. 0.72

  Alignments for each domain:
  == domain 1  score: 26.2 bits;  conditional E-value: 1.2e-08
                 EEEETTSSEEEEEESTTSSHHHHHHHHHHHCTT.TTTTTTCHC.CCCCC--BTTCSSTTEEEEEEEEEETTEESSSSSSCEEEEEEEETTSEEEEEETT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  18 vilpfsksftaivGpNGSGKsnlldAilFvLGersakklrsek.lsdlihkskekasvkkaeveitfdnedkklkiekeevsisrrvkrkgeseyking 115
                   l++ +++t+i+Gp GSGKs ll++i   +Ge++ k    +k l+++ +  ++++ + + +++  ++n +++  i+++++  +  +   +e    i g
  EEA19551.1 628 LRLDIGNGITIIIGPVGSGKSALLESI---IGETHLKDGTTTKpLTRVAY-CSQNPWIINNTIKFNITNGSEH--IDQKWYDFTIWACALEEDLKSIPG 720
                 56788999*******************...9*876665443331444444.4778888888877776666665..777777777766666664445555 PP

                 EEE-HHHHHHHHHCTT-STTCS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHH.....CTTSEEEEE-SSHHHCCC-SCEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 116 kevtkkevsellesagiskelLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkek.....sknaQfivislreemlekadklv 209
                  +  +         +g +  +LSgG+k+ vala       +++ p+++lD++ + LD + +  ++++l  +     ++ + ++  +++++ml  ad+++
  EEA19551.1 721 GDQFQ---------TGSNGVSLSGGQKQRVALA----RAVYSRLPIVILDDVFSGLDSHSTMLISTRLFDQdghfrKTGTSVVLATHTQRMLPYADRII 806
                 44322.........3445557*******98876....55799***********************9997541111133478899999999999999988 PP

                 EE CS
                 xx RF
       SMC_N 210 gv 211
                  +
  EEA19551.1 807 AL 808
                 65 PP

  == domain 2  score: 16.0 bits;  conditional E-value: 1.6e-05
                  EEEEESTTSSHHHHHHHHHHHCTT.TTT.TTTCHCCCCCC--BTTCSSTTEEEEEEEEEETTEESSSSSSCEEEEEEEETTSEEEEEETTEEE-HHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N   27 taivGpNGSGKsnlldAilFvLGersak.klrseklsdlihkskekasvkkaeveitfdnedkklkiekeevsisrrvkrkgeseykingkevtkke 122 
                   ai Gp GSGK++l+ A+l ++  +s + ++ s++ls++  + + + +++    e +f     +++++ +e ++s + ++    ++ + ++   +  
  EEA19551.1 1251 VAICGPSGSGKTSLVMALLQMINLQSGRiEIDSRDLSAIECA-DLRTRINVIPQEPFFMPGTVRFNMDPSENKVSDETIEAALAKVGLWKRISANGG 1346
                  589999999999999999888888776434555555555444.555556655556666666666666666666666666666666666555555555 PP

                  HHHHHHCTT-STTCS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC-SCEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  123 vsellesagiskelLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQfivislreemlekadklv 209 
                  ++  l ++       S Ge++L+ala  + +    ++++ +lDe+ +  D +  +++ ++++++ ++  +i + +r + + + d++v
  EEA19551.1 1347 LEMALVMS-----DWSVGERQLLALARALTM----KSSILVLDEVTSSVDWETEAIMQDVIEKEFSTQTVIAVVHRFRYIDRFDRVV 1424
                  54444443.....5799*****999877655....5789*************************98888999999998888888776 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.7   0.1   0.00011     0.042       1      19 [.     636     654 ..     636     732 .. 0.82
   2 !    7.4   0.0    0.0087       3.4     236     297 ..     732     794 ..     729     798 .. 0.87
   3 !    9.4   0.0    0.0021      0.83       3      24 ..    1252    1273 ..    1251    1311 .. 0.80
   4 ?    4.0   0.0     0.096        37     234     271 ..    1353    1387 ..    1343    1404 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 0.00011
      AAA_21   1 lnvliGpNgsGKSnLLdal 19 
                 ++++iGp gsGKS LL+ +
  EEA19551.1 636 ITIIIGPVGSGKSALLESI 654
                 79***************98 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0087
      AAA_21 236 elSdGtkrllalltallralkkgsllliDEpEngLHPkllrrll.ell...kelsrngaQviltTH 297
                 +lS G+k+  al+ a++++l   +++++D++ +gL+ + +  +  +l+      +++g+ v+l+TH
  EEA19551.1 732 SLSGGQKQRVALARAVYSRL---PIVILDDVFSGLDSHSTMLIStRLFdqdGHFRKTGTSVVLATH 794
                 5899999999********99...*********************777765544444999******* PP

  == domain 3  score: 9.4 bits;  conditional E-value: 0.0021
      AAA_21    3 vliGpNgsGKSnLLdaldllar 24  
                  ++ Gp gsGK++L  al  +  
  EEA19551.1 1252 AICGPSGSGKTSLVMALLQMIN 1273
                  799**************88753 PP

  == domain 4  score: 4.0 bits;  conditional E-value: 0.096
      AAA_21  234 arelSdGtkrllalltallralkkgsllliDEpEngLH 271 
                  +++ S G ++llal+ al       s+l++DE+ ++ +
  EEA19551.1 1353 MSDWSVGERQLLALARALTMKS---SILVLDEVTSSVD 1387
                  566699*****99999999866...********99976 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   7.3e-06    0.0028      81     132 ..     616     667 ..     607     673 .. 0.88
   2 ?   -1.7   0.0         6   2.3e+03      37      79 ..     858     900 ..     848     903 .. 0.77
   3 !   14.0   0.0   9.2e-05     0.036      91     131 ..    1239    1280 ..    1222    1285 .. 0.79

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 7.3e-06
                  E--TTTHTTHHHHHHHCTTSEEEEECSTTSSHHHHHHHHCTT-----S---- CS
  RsgA_GTPase  81 lvsaktkegleelkellkdktsvlvGqSGvGKStLinallpelelktgevse 132
                   +s +t++ le+l+  + + +++++G+ G GKS+L++++++e++lk g + +
   EEA19551.1 616 SWSPETETVLENLRLDIGNGITIIIGPVGSGKSALLESIIGETHLKDGTTTK 667
                  567889999*********************************9998777665 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 6
                  HHHHHHHHTT-EEEEEEE-GGG--HHHHHHHHHHHHHHTTSEE CS
  RsgA_GTPase  37 rfLvlaeekgiepvivlnKiDlleeeeeleelkeelealgyev 79 
                  r  +    +g e  +v+ K Dl  ++ +++ +k  ++++gy++
   EEA19551.1 858 RKATKTGINGSEEALVIKKQDLSRRNGTWDVYKYYVKSAGYKT 900
                  555555566778899*********9999999999999999986 PP

  == domain 3  score: 14.0 bits;  conditional E-value: 9.2e-05
                   HHHHHHCTT.SEEEEECSTTSSHHHHHHHHCTT-----S--- CS
  RsgA_GTPase   91 eelkellkd.ktsvlvGqSGvGKStLinallpelelktgevs 131 
                   ++l+ +++  + ++++G+SG GK++L+ all+  +l+ g + 
   EEA19551.1 1239 KNLSLKINAgEKVAICGPSGSGKTSLVMALLQMINLQSGRIE 1280
                   55666665558899******************9999988875 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.0   0.6   4.2e-06    0.0016      11      39 ..     626     654 ..     623     656 .. 0.91
   2 !   12.8   0.0   0.00033      0.13      23      43 ..    1252    1272 ..    1239    1303 .. 0.84

  Alignments for each domain:
  == domain 1  score: 19.0 bits;  conditional E-value: 4.2e-06
      AAA_23  11 rdqeidFskgltlItGpNGaGKTTildAi 39 
                 ++  +d ++g+t+I+Gp G+GK+++l+ i
  EEA19551.1 626 ENLRLDIGNGITIIIGPVGSGKSALLESI 654
                 5778999********************98 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 0.00033
      AAA_23   23 lItGpNGaGKTTildAiklaL 43  
                  +I+Gp G+GKT+++ A+  + 
  EEA19551.1 1252 AICGPSGSGKTSLVMALLQMI 1272
                  8***************97665 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.2     3e-05     0.012      19      42 ..     630     654 ..     623     656 .. 0.78
   2 !   12.7   0.1    0.0002     0.078      17      43 ..    1243    1269 ..    1238    1276 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 3e-05
      AAA_29  19 idlkg.atlltGpsGsGKSTllDAi 42 
                 +d  + +t+++Gp GsGKS+ll +i
  EEA19551.1 630 LDIGNgITIIIGPVGSGKSALLESI 654
                 4444449**************9776 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 0.0002
      AAA_29   17 ieidlkgatlltGpsGsGKSTllDAiq 43  
                  ++i+  + + + GpsGsGK++l+ A+ 
  EEA19551.1 1243 LKINAGEKVAICGPSGSGKTSLVMALL 1269
                  677755599*************97764 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   7.6e-05     0.029       5     127 ..     634     791 ..     631     797 .. 0.58
   2 !   11.6   0.0   0.00065      0.25       9      48 ..    1252    1292 ..    1248    1305 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 7.6e-05
      AAA_22   5 agilvvtGesGtGKTtllrrlleqldeeakaee..............erpevv....fvtlpsst.....sskdllrellralglelka........er 72 
                  gi++++G++G+GK+ ll+ +  + +     ++                   +    ++++++++     ++ d+  + +  l+++lk+         +
  EEA19551.1 634 NGITIIIGPVGSGKSALLESIIGETHLKDGTTTkpltrvaycsqnpwI----InntiKFNITNGSehidqKWYDFTIWACA-LEEDLKSipggdqfqTG 727
                 699****************99888765544444677777777633332....23333666666666666666666666664.34445555666666533 PP

      AAA_22  73 lsseell.ealeqalrarav...ielliiDEaqh.lr.seealeeLrsllnl...srkgvqliL 127
                  +   l   + ++ + arav    +++i+D++   l+ + ++l   r +  +   +++g++++L
  EEA19551.1 728 SNGVSLSgGQKQRVALARAVysrLPIVILDDVFSgLDsHSTMLISTRLFDQDghfRKTGTSVVL 791
                 3333333445555555555555555666666666665335555444444444555555555555 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 0.00065
      AAA_22    9 vvtGesGtGKTtllrrlleqldeeakaee.erpevvfvtlp 48  
                  +++G+sG+GKT l+  ll+  + ++   e  ++++  ++++
  EEA19551.1 1252 AICGPSGSGKTSLVMALLQMINLQSGRIEiDSRDLSAIECA 1292
                  79***********9999998766555554555555555555 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.8   0.0    0.0012      0.47      12      45 ..     624     655 ..     618     778 .. 0.79
   2 !   15.8   0.0   3.5e-05     0.014      21      89 ..    1247    1316 ..    1237    1395 .. 0.59

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.0012
      AAA_16  12 LlsalervrsgrpelvllsGesGvGKsslvrell 45 
                 +l+ l+ +  g  ++++++G+ G+GKs+l++++ 
  EEA19551.1 624 VLENLR-LDIGN-GITIIIGPVGSGKSALLESII 655
                 444444.44444.799**************9875 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 3.5e-05
      AAA_16   21 sgrpelvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipysalaqalareellrqllde...........a 89  
                  +g  e v + G+sG+GK+slv +ll+ ++ +    ++ + ++l         +++++ ++ ++ + +e            
  EEA19551.1 1247 AG--EKVAICGPSGSGKTSLVMALLQMINLQ-SGRIEIDSRDL-------SAIECADLRTRINVIPQEpffmpgtvrfnM 1316
                  44..56999****************988877.22233333333.......366777777777777777666665555553 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.3   0.00057      0.22      14      43 ..     625     654 ..     624     696 .. 0.86
   2 !   15.5   0.0   2.7e-05      0.01      17      83 ..    1243    1304 ..    1238    1405 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00057
      AAA_15  14 lkdveidlseeltvliGkNnsGKSsileal 43 
                 l++  +d+ + +t++iG+ +sGKS +le +
  EEA19551.1 625 LENLRLDIGNGITIIIGPVGSGKSALLESI 654
                 578899**********************98 PP

  == domain 2  score: 15.5 bits;  conditional E-value: 2.7e-05
      AAA_15   17 veidlseeltvliGkNnsGKSsilealdlFlnnkekknkkvikiekedleifeniseskdikIdvef 83  
                   +i+  e    ++G+ +sGK+s+++al  ++n +    +  i i++ dl+  e+ +   +i +  ++
  EEA19551.1 1243 LKINAGE-KVAICGPSGSGKTSLVMALLQMINLQ----SGRIEIDSRDLSAIECADLRTRINVIPQE 1304
                  4677777.99**********************98....88999999999999888887777766665 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.0      0.02       7.6       2      38 ..     638     731 ..     637     805 .. 0.54
   2 !   14.9   0.0   6.9e-05     0.027       2      95 ..    1252    1400 ..    1251    1427 .. 0.70

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.02
                 EEESSTTSSHHHHHHHHHHHHTHE..........................EEEEETTTCSSS...............................S CS
         AAA   2 llyGppGtGKTllakavakelgve..........................fleisgsellsk...............................y 38 
                 +++Gp G GK++l ++++ e++ +                          f  ++gse +++                               +
  EEA19551.1 638 IIIGPVGSGKSALLESIIGETHLKdgtttkpltrvaycsqnpwiinntikFNITNGSEHIDQkwydftiwacaleedlksipggdqfqtgsngV 731
                 689*****************74332333333333334444444444444466666666663335555555555555555555555555555543 PP

  == domain 2  score: 14.9 bits;  conditional E-value: 6.9e-05
                  EEESSTTSSHHHHHHHHHHHHTHE..........EEEEETTTCSSS................................................... CS
         AAA    2 llyGppGtGKTllakavakelgve..........fleisgsellsk................................................... 37  
                   ++Gp G GKT+l+ a+ + ++ +          +  i++++l+                                                     
  EEA19551.1 1252 AICGPSGSGKTSLVMALLQMINLQsgrieidsrdLSAIECADLRTRinvipqepffmpgtvrfnmdpsenkvsdetieaalakvglwkrisanggle 1348
                  579*****************86332322233333666666666644888888888888888888888888899999999999999999999999999 PP

                  ......STTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHH CS
         AAA   38 ......yvgesekkirelfkeakekakpsilfiDEidalaksrsgseseeeervvnqLlteldg 95  
                         ++ +e+++ +l +++  k+  sil++DE+ + +  +          + + +  ++++
  EEA19551.1 1349 malvmsDWSVGERQLLALARALTMKS--SILVLDEVTSSVDWE----------TEAIMQDVIEK 1400
                  99966656666666666666555554..999999998877666..........44444444444 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.9   0.0    0.0075       2.9     115     153 ..     621     658 ..     578     665 .. 0.70
   2 !   13.1   0.0   9.4e-05     0.037     116     160 ..    1235    1279 ..    1217    1297 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0075
       T2SSE 115 kekiaevlrkavrerglilvsGgTgsGKttllyallkei 153
                 +e++ e lr     +g+ ++ G+ gsGK+ ll +++ e 
  EEA19551.1 621 TETVLENLRLD-IGNGITIIIGPVGSGKSALLESIIGET 658
                 36677778888.456777888***********9998875 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 9.4e-05
       T2SSE  116 ekiaevlrkavrerglilvsGgTgsGKttllyallkeinksderi 160 
                  + i + l+  +++   + + G+ gsGKt l+ all++in ++ ri
  EEA19551.1 1235 PPILKNLSLKINAGEKVAICGPSGSGKTSLVMALLQMINLQSGRI 1279
                  567777888889999999*********************998887 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.4   0.00051       0.2       2      24 ..     636     658 ..     635     666 .. 0.83
   2 !    8.2   0.0    0.0045       1.8       4      23 ..    1252    1271 ..    1249    1286 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00051
                 EEEEEESTTCCHHHHHHHHHCT- CS
        cobW   2 vtvltGflGsGKTtLlnhllenr 24 
                 +t++ G++GsGK++Ll++++ ++
  EEA19551.1 636 ITIIIGPVGSGKSALLESIIGET 658
                 689****************9443 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.0045
                  EEEESTTCCHHHHHHHHHCT CS
        cobW    4 vltGflGsGKTtLlnhllen 23  
                   ++G+ GsGKT+L+ +ll+ 
  EEA19551.1 1252 AICGPSGSGKTSLVMALLQM 1271
                  699*************9964 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0     0.039        15       3      23 ..     638     658 ..     636     673 .. 0.75
   2 !   12.4   0.0   0.00031      0.12       2      59 ..    1251    1312 ..    1250    1402 .. 0.65

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.039
                 EEE--SSSSHHHHHHHGGGGB CS
       AAA_5   3 lLvGppGtgKselaerlaaal 23 
                 +++Gp G+gKs l e++   +
  EEA19551.1 638 IIIGPVGSGKSALLESIIGET 658
                 89************9986555 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 0.00031
                  EEEE--SSSSHHHHHHHGGGGBS--E.EEEE--TT...--HHHHH--B--.........--- CS
       AAA_5    2 vlLvGppGtgKselaerlaaalnrev.eyvqltrd...tteedlkgrreikngttslvdspl 59  
                  v + Gp+G+gK++l++ l++++n +   +   +rd   ++ +dl+ r+++ +++  + ++ +
  EEA19551.1 1251 VAICGPSGSGKTSLVMALLQMINLQSgRIEIDSRDlsaIECADLRTRINVIPQEPFFMPGTV 1312
                  5678******************5433033333333111344666666666666555555555 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   2.2e-05    0.0084       2      40 ..     638     674 ..     637     725 .. 0.75
   2 ?    3.7   0.0      0.14        56       1      21 [.    1251    1271 ..    1251    1286 .. 0.87

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 2.2e-05
                 EEEEBTTTTHHHHHHHHHTS--S---SSS---S-EEEEE CS
   Dynamin_N   2 avvGsqSsGKSSvlnaLlgedilprgpnptTrrplelql 40 
                 +++G + sGKS++l++++ge   + + + tT  ++ + +
  EEA19551.1 638 IIIGPVGSGKSALLESIIGET--HLKDGTTTKPLTRVAY 674
                 589******************..5566677777777776 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.14
                  EEEEEBTTTTHHHHHHHHHTS CS
   Dynamin_N    1 iavvGsqSsGKSSvlnaLlge 21  
                  +a++G   sGK+S++ aLl+ 
  EEA19551.1 1251 VAICGPSGSGKTSLVMALLQM 1271
                  79****************985 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.2    0.0029       1.1       3      42 ..     638     674 ..     636     697 .. 0.81
   2 ?    7.5   0.0     0.011       4.2       1      28 [.    1250    1278 ..    1250    1314 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.0029
                 EEEESTTSSHHHHHHHHHTSTEEESSSTTSSSSEEEEEEE CS
    MMR_HSR1   3 aivGrpNvGKStLinaltgekaivsdkpgtTrdinegrvk 42 
                 +i+G   +GKS L+ +++ge   +  k gtT+++ ++   
  EEA19551.1 638 IIIGPVGSGKSALLESIIGE---THLKDGTTTKPLTRVAY 674
                 69****************95...66778888888776554 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.011
                  EEEEEESTTSSHHHHHHHHHTS.TEEESS CS
    MMR_HSR1    1 evaivGrpNvGKStLinaltge.kaivsd 28  
                  +vai G + +GK++L+ al++  + + ++
  EEA19551.1 1250 KVAICGPSGSGKTSLVMALLQMiNLQSGR 1278
                  69*****************9864444444 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.0     0.045        18       2      22 ..     637     657 ..     636     674 .. 0.86
   2 !   11.4   0.0   0.00071      0.28       2      22 ..    1251    1271 ..    1251    1331 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.045
      AAA_33   2 vllvGlpGsGKstlaerllkk 22 
                 ++++G+ GsGKs l+e+++ +
  EEA19551.1 637 TIIIGPVGSGKSALLESIIGE 657
                 689************998755 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00071
      AAA_33    2 vllvGlpGsGKstlaerllkk 22  
                  v ++G++GsGK+ l+  ll+ 
  EEA19551.1 1251 VAICGPSGSGKTSLVMALLQM 1271
                  568*************99874 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.36   1.4e+02      50      71 ..     637     659 ..     610     672 .. 0.82
   2 !   11.9   0.0   0.00034      0.13      44      68 ..    1245    1269 ..    1225    1278 .. 0.89
   3 ?    1.0   0.1      0.81   3.1e+02     106     144 ..    1371    1408 ..    1358    1423 .. 0.81

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.36
   IstB_IS21  50 ivllGpsGvGKshlaial.gvea 71 
                  +++Gp G GKs l  ++ g   
  EEA19551.1 637 TIIIGPVGSGKSALLESIiGETH 659
                 589*********98776425555 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 0.00034
   IstB_IS21   44 iekkenivllGpsGvGKshlaialg 68  
                  i++ e ++++GpsG GK+ l +al 
  EEA19551.1 1245 INAGEKVAICGPSGSGKTSLVMALL 1269
                  77899*****************985 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 0.81
   IstB_IS21  106 llkvdllilDdlgllpldqaeaellfeviekryerrsii 144 
                   +k+++l+lD++    +d + ++ + +viek + ++++i
  EEA19551.1 1371 TMKSSILVLDEVT-SSVDWETEAIMQDVIEKEFSTQTVI 1408
                  45779******96.6899999999*******99998876 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.2   0.2    0.0013       0.5      20      47 ..     634     661 ..     622     764 .. 0.87
   2 ?    6.1   0.0     0.024       9.5      23      48 ..    1251    1277 ..    1239    1411 .. 0.67

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.0013
    ATPase_2  20 neiyfiYGpegsGKtaLlkeiienledk 47 
                 n i  i Gp gsGK+aLl  ii + + k
  EEA19551.1 634 NGITIIIGPVGSGKSALLESIIGETHLK 661
                 56899****************9877444 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.024
    ATPase_2   23 yfiYGpegsGKtaLlkeiienl.edkd 48  
                  + i Gp gsGKt+L++ +++   ++++
  EEA19551.1 1251 VAICGPSGSGKTSLVMALLQMInLQSG 1277
                  5699**********9988876634444 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   0.0    0.0066       2.6       3      23 ..     637     657 ..     636     681 .. 0.83
   2 !    8.1   0.0     0.006       2.4       3      23 ..    1251    1271 ..    1249    1283 .. 0.87

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0066
                 EEEEC-TTTCHHHHHHHHHHH CS
       NACHT   3 vilqGeaGsGKTtLlqklala 23 
                  i+ G+ GsGK++Ll++++ +
  EEA19551.1 637 TIIIGPVGSGKSALLESIIGE 657
                 589***************865 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.006
                  EEEEC-TTTCHHHHHHHHHHH CS
       NACHT    3 vilqGeaGsGKTtLlqklala 23  
                  v++ G++GsGKT L+  l + 
  EEA19551.1 1251 VAICGPSGSGKTSLVMALLQM 1271
                  7899***********999875 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0      0.23        91      32      50 ..     633     651 ..     608     673 .. 0.82
   2 ?    0.8   0.0      0.81   3.1e+02     132     190 ..     742     796 ..     713     798 .. 0.79
   3 !   10.3   0.0   0.00097      0.38      11      53 ..    1227    1268 ..    1221    1276 .. 0.79

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.23
      AAA_25  32 agelallaGapgtGKttla 50 
                  +++++++G+ g+GK++l+
  EEA19551.1 633 GNGITIIIGPVGSGKSALL 651
                 5789************998 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.81
      AAA_25 132 aleaaieevegvrlvviDplsralggdensnsdv.galvealeriarrtgaavllvhHvg 190
                 al++a+ +  ++  v++D +  + g d++s   + ++l+++  ++ r+tg  v+l  H+ 
  EEA19551.1 742 ALARAVYS--RLPIVILDDV--FSGLDSHSTMLIsTRLFDQDGHF-RKTGTSVVLATHTQ 796
                 45555555..3888999865..5566999999999*********9.7***********96 PP

  == domain 3  score: 10.3 bits;  conditional E-value: 0.00097
      AAA_25   11 svadlaapppprrwlvkgllpagelallaGapgtGKttlaldl 53  
                  ++ +++ +pp ++ l    + age ++++G++g+GKt l++ l
  EEA19551.1 1227 TATHSDDSPPILKNLSLK-INAGEKVAICGPSGSGKTSLVMAL 1268
                  455566677777755555.59******************9987 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.0      0.11        42      36      57 ..     637     658 ..     628     678 .. 0.80
   2 !   10.9   0.0    0.0006      0.23      28      58 ..    1243    1273 ..    1237    1288 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.11
       AAA_7  36 vllvGptGtGKtviikdllkkl 57 
                 ++++Gp+G+GK++++++++ + 
  EEA19551.1 637 TIIIGPVGSGKSALLESIIGET 658
                 5789**********99976554 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.0006
       AAA_7   28 lllknkkpvllvGptGtGKtviikdllkkld 58  
                  l ++++ +v ++Gp+G+GKt++++ ll+ ++
  EEA19551.1 1243 LKINAGEKVAICGPSGSGKTSLVMALLQMIN 1273
                  5678999******************999876 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0     0.044        17       3      31 ..     638     666 ..     637     720 .. 0.72
   2 !    9.0   0.0    0.0039       1.5       1      21 [.    1250    1270 ..    1250    1294 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.044
                 EEESSTTSSHHHHHHCHCT-CCC-EEETT CS
         Roc   3 vlvGdsgvGKtsllkrfvedkfsekekst 31 
                 +++G  g+GK+ ll++++ ++  ++ ++t
  EEA19551.1 638 IIIGPVGSGKSALLESIIGETHLKDGTTT 666
                 79****************98876654444 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.0039
                  EEEEESSTTSSHHHHHHCHCT CS
         Roc    1 KvvlvGdsgvGKtsllkrfve 21  
                  Kv ++G sg+GKtsl+  +++
  EEA19551.1 1250 KVAICGPSGSGKTSLVMALLQ 1270
                  899*************99875 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.2     0.044        17       8      46 ..     624     660 ..     619     771 .. 0.80
   2 !   10.8   0.6   0.00051       0.2      19     124 ..    1248    1393 ..    1235    1408 .. 0.68

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.044
                 HHHHHHCTTTSCSEEEEEEESTTSSHHHHHHHHCCSHCC CS
      NB-ARC   8 viekLlekdelqslvvalvGmgGvGKttlakqilnksde 46 
                 v e+L    +++  +  + G  G+GK+ l+++i+ + + 
  EEA19551.1 624 VLENLR--LDIGNGITIIIGPVGSGKSALLESIIGETHL 660
                 566665..4566668999**************9987544 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00051
                  CSEEEEEEESTTSSHHHHHHHHCCSHCCCCCCBTEEEEE.........................................EEESXXHHHHHHHXXHH CS
      NB-ARC   19 qslvvalvGmgGvGKttlakqilnksdevegrFdsvawv.........................................vvsktdkseeiletilk 74  
                  +   va+ G  G+GKt l+   l+  +   gr ++                                             ++     +  ++++i +
  EEA19551.1 1248 G-EKVAICGPSGSGKTSLVMALLQMINLQSGRIEIDSRDlsaiecadlrtrinvipqepffmpgtvrfnmdpsenkvsdeTIEAALAKVGLWKRISA 1343
                  4.45899999999999999888888555555555332223566789999999999999999999999999999995555533333344445555555 PP

                  HHHCCCTTSSSS-STTS.HHHHHHHHCCCTTEEEEEEEE-SHHHH.....H CS
      NB-ARC   75 eLslseddleekeeves.lkrklvrlLltkrfllvlDDVweeedwdkigvv 124 
                  + +l+ +   +  +v +     l r+L  k ++lvlD V  ++dw+   + 
  EEA19551.1 1344 NGGLEMALVMSDWSVGErQLLALARALTMKSSILVLDEVTSSVDWET-EAI 1393
                  5444433332222222236689***********************54.444 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.0     0.045        18      17      62 ..     634     677 ..     621     697 .. 0.80
   2 !    8.5   0.0    0.0039       1.5      15      44 ..    1246    1275 ..    1237    1313 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.045
      AAA_11  17 seitliqGPPGtgKTktivellsqllsrrkseeeksakpriLvCap 62 
                 ++it+i GP G+gK+  + +++ + +   k  ++ ++  r+ +C++
  EEA19551.1 634 NGITIIIGPVGSGKSALLESIIGETHL--KDGTTTKPLTRVAYCSQ 677
                 558*******************99954..34566677777777765 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0039
      AAA_11   15 seseitliqGPPGtgKTktivellsqllsr 44  
                  +  e + i GP G+gKT+ +++ll++++ +
  EEA19551.1 1246 NAGEKVAICGPSGSGKTSLVMALLQMINLQ 1275
                  5556689******************99633 PP

>> ATP_bind_1  Conserved hypothetical ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.1      0.12        45       1      17 [.     639     655 ..     639     665 .. 0.84
   2 ?    8.4   0.0    0.0043       1.7       1      23 [.    1253    1275 ..    1253    1282 .. 0.88

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.12
  ATP_bind_1   1 vvGpaGsGKttfvgals 17 
                 ++Gp+GsGK+ + ++++
  EEA19551.1 639 IIGPVGSGKSALLESII 655
                 79*********999876 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0043
  ATP_bind_1    1 vvGpaGsGKttfvgalseilelr 23  
                  ++Gp GsGKt++v al ++++l+
  EEA19551.1 1253 ICGPSGSGKTSLVMALLQMINLQ 1275
                  79***************999876 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.0     0.022       8.6      17      46 ..     633     663 ..     625     677 .. 0.78
   2 ?    6.0   0.0     0.022       8.7      21      49 ..    1251    1279 ..    1243    1410 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.022
      AAA_30  17 gdrvavltGpAGtGKttalkal.reaweaag 46 
                 g+ ++++ Gp G+GK+ +l+++  e++ ++g
  EEA19551.1 633 GNGITIIIGPVGSGKSALLESIiGETHLKDG 663
                 45699**************998555555555 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.022
      AAA_30   21 avltGpAGtGKttalkalreaweaaggrv 49  
                  +++ Gp G+GKt ++ al ++++ + gr+
  EEA19551.1 1251 VAICGPSGSGKTSLVMALLQMINLQSGRI 1279
                  5789*************999998775555 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.1      0.53   2.1e+02       2      17 ..     638     653 ..     638     675 .. 0.88
   2 ?    9.8   0.0    0.0028       1.1       1      24 [.    1251    1274 ..    1251    1312 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.53
      AAA_18   2 lltGtpGvGKttlake 17 
                 ++ G+ G+GK+ l + 
  EEA19551.1 638 IIIGPVGSGKSALLES 653
                 699********99876 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.0028
      AAA_18    1 IlltGtpGvGKttlakeLskrlgf 24  
                  ++++G++G+GKt+l  +L ++ ++
  EEA19551.1 1251 VAICGPSGSGKTSLVMALLQMINL 1274
                  78************9999776554 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0      0.36   1.4e+02       2      21 ..     638     657 ..     637     680 .. 0.79
   2 ?    9.1   0.0    0.0044       1.7       2      25 ..    1252    1275 ..    1251    1288 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.36
  RNA_helicase   2 wlyGpsgeGKStlakeLaka 21 
                   ++ Gp g GKS l ++++ +
    EEA19551.1 638 IIIGPVGSGKSALLESIIGE 657
                   589***********998755 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.0044
  RNA_helicase    2 wlyGpsgeGKStlakeLakallkk 25  
                     ++Gpsg GK++l+  L + +  +
    EEA19551.1 1252 AICGPSGSGKTSLVMALLQMINLQ 1275
                    69**************99988744 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.0     0.054        21       3      27 ..     635     659 ..     633     684 .. 0.86
   2 ?    3.1   0.0      0.23        88       5      40 ..    1251    1285 ..    1248    1310 .. 0.66
   3 ?    1.5   0.0      0.74   2.9e+02      63      81 ..    1372    1390 ..    1354    1406 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.054
      AAA_14   3 kilvitGaRrvGKTtllkqlikell 27 
                  i +i G+  +GK+ ll+ +i e  
  EEA19551.1 635 GITIIIGPVGSGKSALLESIIGETH 659
                 689****************997765 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.23
      AAA_14    5 lvitGaRrvGKTtllkqlikellvkkesilyinldd 40  
                  ++i G+  +GKT l+  l++     ++  ++i+  d
  EEA19551.1 1251 VAICGPSGSGKTSLVMALLQMIN-LQSGRIEIDSRD 1285
                  6899***********99987655.223333333333 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.74
      AAA_14   63 ekktylflDEiqevpewek 81  
                   k ++l+lDE+  + +we+
  EEA19551.1 1372 MKSSILVLDEVTSSVDWET 1390
                  36789************96 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   0.1     0.022       8.7       8      50 ..     632     674 ..     626     687 .. 0.81
   2 ?    5.6   0.4     0.049        19      11      38 ..    1249    1276 ..    1243    1410 .. 0.71

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.022
      AAA_19   8 lkekvllvtaGpGtGKTrvlkhivallvelggvkpeeillvaf 50 
                 + +++ +++++ G+GK+ +l+ i+ +     g   ++++ va+
  EEA19551.1 632 IGNGITIIIGPVGSGKSALLESIIGETHLKDGTTTKPLTRVAY 674
                 567899******************8877777766666666666 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.049
      AAA_19   11 kvllvtaGpGtGKTrvlkhivallvelg 38  
                  + +++ ++ G+GKT ++++ +++++ + 
  EEA19551.1 1249 EKVAICGPSGSGKTSLVMALLQMINLQS 1276
                  568899***********99998876555 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.1      0.15        59      42      60 ..     637     655 ..     622     657 .. 0.89
   2 ?    8.5   0.1     0.003       1.2      41      61 ..    1250    1270 ..    1235    1275 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.15
                   EEEE--TTSSHHHHHHHHH CS
  FtsK_SpoIIIE  42 llvaGatgsGKStalntLi 60 
                   ++++G  gsGKS  l ++i
    EEA19551.1 637 TIIIGPVGSGKSALLESII 655
                   69*************9998 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.003
                    SEEEE--TTSSHHHHHHHHHH CS
  FtsK_SpoIIIE   41 hllvaGatgsGKStalntLil 61  
                     + ++G +gsGK+  +++L++
    EEA19551.1 1250 KVAICGPSGSGKTSLVMALLQ 1270
                    789****************86 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0       0.2        77      10      45 ..     624     660 ..     617     668 .. 0.71
   2 ?    7.7   0.0    0.0084       3.3      18      46 ..    1245    1275 ..    1230    1284 .. 0.77

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.2
                 HHHHHHHCH.TEEEEEEESTTSSHHHHHHHHHHHTT- CS
        TsaE  10 lgkklakal.gdvilLeGdLGaGKTtlvrglakalgv 45 
                 + ++l   + + + ++ G++G+GK++l  +++ + ++
  EEA19551.1 624 VLENLRLDIgNGITIIIGPVGSGKSALLESIIGETHL 660
                 44555444444568899***********999977665 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0084
                  H..TEEEEEEESTTSSHHHHHHHHHHHTT-- CS
        TsaE   18 l..gdvilLeGdLGaGKTtlvrglakalgve 46  
                  +  g+ +++ G+ G+GKT lv +l++ ++++
  EEA19551.1 1245 InaGEKVAICGPSGSGKTSLVMALLQMINLQ 1275
                  23377899******************99876 PP

>> PhoH  PhoH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.0     0.039        15      12      35 ..     624     650 ..     617     669 .. 0.77
   2 ?    4.9   0.0      0.04        16      16      39 ..    1245    1268 ..    1239    1285 .. 0.78
   3 ?   -2.1   0.0       5.4   2.1e+03     110     128 ..    1364    1382 ..    1307    1395 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.039
                 HHHHHH...H-SEEEEE--TTSSTTHH CS
        PhoH  12 ylealk...kndivfaiGpaGtGKtyl 35 
                 +le+l+    n i+++iGp G+GK+ l
  EEA19551.1 624 VLENLRldiGNGITIIIGPVGSGKSAL 650
                 556666656789************976 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.04
                  HHH-SEEEEE--TTSSTTHHHHHH CS
        PhoH   16 lkkndivfaiGpaGtGKtylaval 39  
                  +++ + v + Gp+G+GKt l +al
  EEA19551.1 1245 INAGEKVAICGPSGSGKTSLVMAL 1268
                  556667899*********987664 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 5.4
                  GGGGTT--B-SEEEEE-SG CS
        PhoH  110 laymRGrTlndafvilDEA 128 
                  la  R  T++ ++++lDE 
  EEA19551.1 1364 LALARALTMKSSILVLDEV 1382
                  6788999**********96 PP

>> MobB  Molybdopterin guanine dinucleotide synthesis protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.1       0.7   2.7e+02       3      23 ..     638     658 ..     636     665 .. 0.84
   2 ?    9.2   0.0    0.0027       1.1       2      27 ..    1251    1276 ..    1250    1282 .. 0.85

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.7
        MobB   3 givgksgsGKTtLleklipel 23 
                  i+g  gsGK +Lle +i e 
  EEA19551.1 638 IIIGPVGSGKSALLESIIGET 658
                 588999***********9875 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.0027
        MobB    2 lgivgksgsGKTtLleklipelkarg 27  
                  ++i+g sgsGKT+L+  l+++++ + 
  EEA19551.1 1251 VAICGPSGSGKTSLVMALLQMINLQS 1276
                  689****************9987665 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.0       1.4   5.3e+02      13      35 ..     633     655 ..     622     759 .. 0.87
   2 ?    7.7   0.0    0.0072       2.8      11      38 ..    1245    1271 ..    1236    1291 .. 0.79
   3 ?    0.2   0.0       1.5   5.7e+02     121     147 ..    1373    1399 ..    1354    1409 .. 0.81

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 1.4
                 TTCEEEEEESTTSSHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  13 gggdvlvaaeTGsGKTlaflipv 35 
                 g+g  ++ +++GsGK++     +
  EEA19551.1 633 GNGITIIIGPVGSGKSALLESII 655
                 566788999******99765554 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0072
                  HHTTCEEEEEESTTSSHHHHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   11 ilgggdvlvaaeTGsGKTlaflipvlqi 38  
                  i  g++v ++++ GsGKT    +++lq 
  EEA19551.1 1245 INAGEKVAICGPSGSGKTSLV-MALLQM 1271
                  55799*************984.444444 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 1.5
                  TEEEEEEETHHHHHHTTTHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  121 qvrflVlDEadrlldqgfsdfinriln 147 
                  + ++lVlDE+    d++ +  ++ +++
  EEA19551.1 1373 KSSILVLDEVTSSVDWETEAIMQDVIE 1399
                  5689************99998888776 PP

>> SRPRB  Signal recognition particle receptor beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.082        32       6      37 ..     637     668 ..     634     686 .. 0.77
   2 ?    5.8   0.0     0.021       8.1       5      26 ..    1250    1271 ..    1246    1299 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.082
                 EEEE-STTSSHHHHHHHHHHSS---B---SS- CS
       SRPRB   6 vllvGlsdsGKTslftrLttdsvkktvtSqes 37 
                  +++G+  sGK +l++ +  ++  k  t  ++
  EEA19551.1 637 TIIIGPVGSGKSALLESIIGETHLKDGTTTKP 668
                 69*************99988876665555544 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.021
                  EEEEE-STTSSHHHHHHHHHHS CS
       SRPRB    5 avllvGlsdsGKTslftrLttd 26  
                  +v + G+s sGKTsl   L++ 
  EEA19551.1 1250 KVAICGPSGSGKTSLVMALLQM 1271
                  7889************999875 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0      0.37   1.5e+02      24      42 ..     636     654 ..     630     674 .. 0.84
   2 ?    7.7   0.0    0.0053       2.1      21      81 ..    1247    1309 ..    1238    1312 .. 0.74

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.37
  Mg_chelatase  24 nlllvGppGsGKtmlakrl 42 
                     +++Gp GsGK+ l + +
    EEA19551.1 636 ITIIIGPVGSGKSALLESI 654
                   5689*********997765 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0053
  Mg_chelatase   21 GgHnlllvGppGsGKtmlakrlpsllpplseeealevakiasvag..kkeeekllkrrpfrap 81  
                     g ++ ++Gp+GsGKt l  +l +++   s +  ++++ ++++     +++ +++ + pf  p
    EEA19551.1 1247 AGEKVAICGPSGSGKTSLVMALLQMINLQSGRIEIDSRDLSAIECadLRTRINVIPQEPFFMP 1309
                    4567899***************99998888877777777777655224555666777777655 PP

>> RNA12  RNA12 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.26     1e+02      17      37 ..     634     653 ..     620     661 .. 0.78
   2 ?    7.3   0.0    0.0042       1.6      20      52 ..    1251    1285 ..    1240    1295 .. 0.73

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.26
       RNA12  17 ntFivvkGPrGSGkkeLvldr 37 
                 n  +++ GP GSGk+ L+ + 
  EEA19551.1 634 NGITIIIGPVGSGKSALL-ES 653
                 5667999********997.55 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0042
       RNA12   20 ivvkGPrGSGkkeLvld..rvlkdrkkvlvidCde 52  
                  + + GP GSGk++Lv+   ++++ ++  + id ++
  EEA19551.1 1251 VAICGPSGSGKTSLVMAllQMINLQSGRIEIDSRD 1285
                  7899***********86334555555566666555 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.0     0.014       5.4       7      32 ..     638     663 ..     635     679 .. 0.84
   2 ?    2.0   0.0      0.33   1.3e+02       6      29 ..    1251    1274 ..    1249    1292 .. 0.83

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.014
                 EEEESTTSSHHHHHHHHHHHTTSSCH CS
    GTP_EFTU   7 giighvDhGKtTLtdrLlyktgaisk 32 
                 +iig v +GK+ L+++++ +t+  + 
  EEA19551.1 638 IIIGPVGSGKSALLESIIGETHLKDG 663
                 79****************98887554 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.33
                  EEEEESTTSSHHHHHHHHHHHTTS CS
    GTP_EFTU    6 igiighvDhGKtTLtdrLlyktga 29  
                  ++i+g   +GKt+L+ +Ll+  + 
  EEA19551.1 1251 VAICGPSGSGKTSLVMALLQMINL 1274
                  89****************987665 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.3       1.8   7.1e+02       6      22 ..     638     654 ..     636     667 .. 0.85
   2 ?    9.5   0.0    0.0019      0.75       3      46 ..    1249    1289 ..    1247    1401 .. 0.79

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 1.8
      AAA_24   6 liyGpsgiGKTtlakel 22 
                 +i+Gp g+GK+ l+ ++
  EEA19551.1 638 IIIGPVGSGKSALLESI 654
                 69*********999876 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.0019
      AAA_24    3 lkiliyGpsgiGKTtlakelgpkplfidtekGlksldadkfpdi 46  
                   k++i Gpsg+GKT+l+  l     +i++  G  ++d +++  i
  EEA19551.1 1249 EKVAICGPSGSGKTSLVMAL---LQMINLQSGRIEIDSRDLSAI 1289
                  699*************9888...666666666666666666555 PP

>> Adeno_IVa2  Adenovirus IVa2 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.1    0.0034       1.3      87     110 ..     634     657 ..     620     666 .. 0.81
   2 ?    1.7   0.1      0.24        92      92     109 ..    1253    1270 ..    1236    1277 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0034
  Adeno_IVa2  87 PviGviyGPtGsGksqllrnliss 110
                   i +i GP GsGks ll ++i  
  EEA19551.1 634 NGITIIIGPVGSGKSALLESIIGE 657
                 5689**************999975 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.24
  Adeno_IVa2   92 iyGPtGsGksqllrnlis 109 
                  i GP GsGk+ l+ +l+ 
  EEA19551.1 1253 ICGPSGSGKTSLVMALLQ 1270
                  89************9985 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0       2.1   8.1e+02      57      77 ..     638     658 ..     633     662 .. 0.84
   2 ?    9.3   0.0    0.0014      0.56      52      95 ..    1247    1289 ..    1238    1308 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 2.1
      DUF815  57 LLwGarGtGKSslvkallney 77 
                 +++G  G+GKS+l+ +++ e+
  EEA19551.1 638 IIIGPVGSGKSALLESIIGET 658
                 67899********99988765 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.0014
      DUF815   52 pannvLLwGarGtGKSslvkallneyaeegLrlievekedlkel 95  
                  + ++v + G  G+GK slv all+ ++ ++ r ie++ +dl+ +
  EEA19551.1 1247 AGEKVAICGPSGSGKTSLVMALLQMINLQSGR-IEIDSRDLSAI 1289
                  56788999******************999988.79999999876 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.4       1.3   5.1e+02       3      19 ..     638     654 ..     637     668 .. 0.86
   2 ?    8.0   0.0    0.0082       3.2       1      21 [.    1250    1270 ..    1250    1336 .. 0.95

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 1.3
      AAA_28   3 vitGgestGKTtlleaL 19 
                 +i+G+ ++GK+ lle +
  EEA19551.1 638 IIIGPVGSGKSALLESI 654
                 79***********9875 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0082
      AAA_28    1 kivitGgestGKTtlleaLaa 21  
                  k++i G++++GKT+l+ aL +
  EEA19551.1 1250 KVAICGPSGSGKTSLVMALLQ 1270
                  799*************99965 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.4      0.84   3.3e+02       3      22 ..     638     657 ..     637     667 .. 0.84
   2 ?    6.0   0.0     0.026        10       1      24 [.    1250    1273 ..    1250    1280 .. 0.87
   3 ?    1.6   0.1      0.58   2.3e+02      86     147 ..    1363    1426 ..    1329    1439 .. 0.73

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.84
                 EEE--TTSSHHHHHHHHHHH CS
    NTPase_1   3 fiTGppGvGKtTlvkkvlel 22 
                 +i Gp G+GK+ l++ ++ +
  EEA19551.1 638 IIIGPVGSGKSALLESIIGE 657
                 678************99876 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.026
                  EEEEE--TTSSHHHHHHHHHHHH. CS
    NTPase_1    1 kvfiTGppGvGKtTlvkkvlellk 24  
                  kv+i Gp+G+GKt lv  +l++++
  EEA19551.1 1250 KVAICGPSGSGKTSLVMALLQMIN 1273
                  589**************9999885 PP

  == domain 3  score: 1.6 bits;  conditional E-value: 0.58
                  HHHHHHHH.HHH-EEEE---S.TTGGG-HHHHHHHHHHHTTTSEEEEE--SS--SHHHHHHHT- CS
    NTPase_1   86 lealrkal.seadviviDEiG.kmElkskkfkeaveevLksekpvlavihrrkdlalveeirer 147 
                  l al +al  ++ ++v+DE+  +   +++ + + v e   s + v+av+hr +  +  +++   
  EEA19551.1 1363 LLALARALtMKSSILVLDEVTsSVDWETEAIMQDVIEKEFSTQTVIAVVHRFRYIDRFDRVVLL 1426
                  445555654788899****96257888888877776666677889*****99766666655555 PP

>> ABC_ATPase  Predicted ATPase of the ABC class
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.4     0.019       7.3     242     264 ..     632     654 ..     629     659 .. 0.91
   2 ?   -3.5   0.0       8.7   3.4e+03     386     413 ..     784     810 ..     773     821 .. 0.80
   3 ?   -3.1   0.0       6.5   2.5e+03      26      65 ..    1289    1328 ..    1278    1337 .. 0.68
   4 ?    0.9   0.1      0.39   1.5e+02     332     372 ..    1365    1404 ..    1350    1424 .. 0.79

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.019
                 E-SSEEEEEE-TTSSHHHHHHHH CS
  ABC_ATPase 242 ipkGvtlIvGggfhGKsTLLeAl 264
                 i +G+t+I+G+   GKs LLe++
  EEA19551.1 632 IGNGITIIIGPVGSGKSALLESI 654
                 779******************98 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 8.7
                 HH--EEEEEESS-GCCTTT-SEEEEEET CS
  ABC_ATPase 386 klgvstilvvggsgdyldvAdtvilmee 413
                 k+g s++  +   + +l+ Ad++i++++
  EEA19551.1 784 KTGTSVV-LATHTQRMLPYADRIIALNN 810
                 5555544.56778899*********986 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 6.5
                  EESSSEEEEES---SSTTSS-EEEEEEEE--S-HHSSSSG CS
  ABC_ATPase   26 ydlsdltllidrvqsdpfappSkvrvsvpaavakleeell 65  
                  +++ dl+ +i+++ ++pf  p  vr++++ + +k+++e+ 
  EEA19551.1 1289 IECADLRTRINVIPQEPFFMPGTVRFNMDPSENKVSDETI 1328
                  4455677778888888888888888877777666666655 PP

  == domain 4  score: 0.9 bits;  conditional E-value: 0.39
                  HHHHHHHTT-SEEEEEGGGS-HHHH---HHHHHHS-GGG-- CS
  ABC_ATPase  332 nimealeagakllLiDEDtsAtNlmirDermqelvskekep 372 
                  ++++al +++++l++DE ts +      + mq +++ke  +
  EEA19551.1 1365 ALARALTMKSSILVLDEVTSSVDWET-EAIMQDVIEKEFST 1404
                  6789*****************99877.89999999887643 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1458 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       777  (0.0433376); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                       101  (0.00563333); expected 17.9 (0.001)
Passed Fwd filter:                        46  (0.00256568); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              46  [number of targets reported over threshold]
# CPU time: 1.05u 0.33s 00:00:01.38 Elapsed: 00:00:00.48
# Mc/sec: 9178.16
//
Query:       EEA19552.1  [L=284]
Description: hypothetical protein PMAA_003400 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (284 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       468  (0.026103); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 1968.28
//
Query:       EEA19553.1  [L=275]
Description: deoxyribose-phosphate aldolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-17   64.1   4.3      2e-17   63.6   4.3    1.1  1  DeoC          DeoC/LacD family aldolase
    4.2e-05   22.9   0.4    6.1e-05   22.4   0.4    1.3  1  DHO_dh        Dihydroorotate dehydrogenase
     0.0011   18.5   1.0     0.0022   17.5   0.3    1.8  2  His_biosynth  Histidine biosynthesis protein
  ------ inclusion threshold ------
       0.04   13.4   0.5      0.085   12.3   0.5    1.6  1  PcrB          PcrB family
      0.042   12.9   1.0      0.085   11.9   1.0    1.4  1  FMN_dh        FMN-dependent dehydrogenase


Domain annotation for each model (and alignments):
>> DeoC  DeoC/LacD family aldolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.6   4.3   5.6e-21     2e-17       3     232 ..      41     254 ..      39     258 .. 0.86

  Alignments for each domain:
  == domain 1  score: 63.6 bits;  conditional E-value: 5.6e-21
                 EEEECCSHHHHHHHHCTSSHHHHHHHHHHHHHHGGGSSEEEEETTTHHHHHHCSCT.....TSEEEEETECSSCCTTSTTEEEETTCHHHHHHHTT-SE CS
        DeoC   3 ilavDqrvankddtasaqneqledlkalvkealtpgasavlldpgviasaskeyak.....diallvkldkgtyllkskqrdvdevasveeakalGAda 96 
                 +  +D++ +    t+s       d+ +l++ea + + + v++ +  +++a   +a       +a +v++ +gty + +k      va++ +a+a GA++
  EEA19553.1  41 AHTIDHTQLALSATSS-------DIDNLCTEAREYKFATVCVRLPHVPRAVHNLADiknevGVACVVGFHEGTYPTAEK------VAEATKAVAEGATE 126
                 5568888888888888.......*********************9999999999999999999****************......************** PP

                 EEEEEEEHTTTTCHHHHHHHHHHHHHHHHH..HHTEEEEEEEEE-CTTBSSTTCHHHHHHHHHHHHTCCT-SEEEE--SSCC.B.HHHHHHHHHHHHHC CS
        DeoC  97 vkvvvyyradgseeeqqklaeikrvkeach..eeglplilelylrdeaikdekvdpdlvaeAarvsaelGaDiiKvevpkevvnateedaevfkdvika 193
                 +++v++y  ++ ++ ++++++i +v+ a+   + +l++ile+     +          +  ++ +s  +GaD +K++++  +  a  e ++ +k+v++ 
  EEA19553.1 127 LDMVLNYPLLKQGRYTEVYNDILAVRHAAPapKTKLKVILEISQLSRD---------EIIAGSAISDMAGADYVKTSTGFNGAGASIENVRLMKEVVDM 216
                 ***************************998778999999997544444.........799999****************9999*************995 PP

                 HSSTE.EEEETTSSHHHHHHHHHHHHH..HHTH..CEEEESHHH CS
        DeoC 194 apvpg.vvlsGGvseedfletvedAvk..eaga..sGvlsGRai 232
                     + v+ sGGv      + +edAv+  +aga  +G+++G +i
  EEA19553.1 217 LANGCkVKASGGV------RSAEDAVEmlKAGAdrIGASAGVKI 254
                 544446*******......6666666555566666666666544 PP

>> DHO_dh  Dihydroorotate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.4   0.4   1.7e-08   6.1e-05     219     270 ..     196     246 ..     145     257 .. 0.78

  Alignments for each domain:
  == domain 1  score: 22.4 bits;  conditional E-value: 1.7e-08
                 EEEEEGGGHHHHHHHHHHHHHHTTT.S-EEEESS--SHHHHHHHHHHTECEE CS
      DHO_dh 219 GGlsGkalkdialkvirelykrlkkeipiIgvGGiesgeDalekieaGAslv 270
                 G   G+      ++++ e+ ++l +  ++ ++GG+ s+eDa+e+++aGA  +
  EEA19553.1 196 G-FNGAGASIENVRLMKEVVDMLANGCKVKASGGVRSAEDAVEMLKAGADRI 246
                 3.555555555677888889999999***********************765 PP

>> His_biosynth  Histidine biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0      0.84     3e+03       7      46 ..      89     127 ..      88     130 .. 0.68
   2 !   17.5   0.3   6.2e-07    0.0022      53      99 ..     202     246 ..     199     258 .. 0.87

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.84
                   EEETTEEEEECTTCSTCEEEETTSHHHHHHHHHHHT-SEE CS
  His_biosynth   7 DlkdGkvVrlvkGdrfqelryagdpvelakryeeegadel 46 
                   D+k+   V  v G  + ++  a++++e+ k+  +ega+el
    EEA19553.1  89 DIKNEVGVACVVGFHEGTYPTAEKVAEATKAV-AEGATEL 127
                   67777777777788877777777777766655.6677666 PP

  == domain 2  score: 17.5 bits;  conditional E-value: 6.2e-07
                   HHCTTHHHHHHHHHHHHHH-SSEEEEESSSSSHHHHHHHHHCT-SEE CS
  His_biosynth  53 aakegreanldlveeiaeevfipvqvGGGIrsledveelleagadkv 99 
                   a+ e+ + ++++v  +a+   ++v   GG+rs ed+ e+l+agad++
    EEA19553.1 202 ASIENVRLMKEVVDMLANG--CKVKASGGVRSAEDAVEMLKAGADRI 246
                   5667778888888888888..9999********************97 PP

>> PcrB  PcrB family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.5   2.4e-05     0.085     164     205 ..     203     246 ..     158     258 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 2.4e-05
                 SSS-HHHHHHHHHHHS.SSEEEEESS--SHHHHHHHHCC.SSEE CS
        PcrB 164 aledveevialkkkle.karlivGGGirsaEkAkevvea.ADvi 205
                   e+v ++++++  l  + ++   GG+rsaE+A e+++a AD i
  EEA19553.1 203 SIENVRLMKEVVDMLAnGCKVKASGGVRSAEDAVEMLKAgADRI 246
                 356778999999888515789999******************87 PP

>> FMN_dh  FMN-dependent dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   1.0   2.4e-05     0.085     258     298 ..     207     247 ..     196     254 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 2.4e-05
                 HHCHHHHHHHH..SS-EEEESS--SHHHHHHHHHTT-SEEE CS
      FMN_dh 258 idvLpeiveavggrievlvDgGirrGsDvlkAlalGAdavl 298
                 ++ + e+v+ +++ ++v ++gG+r+ +D++  l  GAd ++
  EEA19553.1 207 VRLMKEVVDMLANGCKVKASGGVRSAEDAVEMLKAGADRIG 247
                 4566999******************************9765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       423  (0.0235931); expected 358.6 (0.02)
Passed bias filter:                      357  (0.0199119); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 1931.13
//
Query:       EEA19554.1  [L=148]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
      0.058   14.0   0.0      0.092   13.4   0.0    1.5  1  SelK_SelG  Selenoprotein SelK_SelG


Domain annotation for each model (and alignments):
>> SelK_SelG  Selenoprotein SelK_SelG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   5.1e-06     0.092       3      42 ..      12      48 ..      10      85 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 5.1e-06
   SelK_SelG  3 isenGqVlekrspwrlsiitdffwgivnfivlFfqtLlsp 42
                is +G+ le  +p+   +i +++ +i  f++l+f tL+s 
  EEA19554.1 12 IS-GGHMLE--TPPLSARIIRWIDRIYLFFGLYFVTLFSR 48
                77.888888..678889*********************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (148 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       432  (0.024095); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 1034.21
//
Query:       EEA19555.1  [L=563]
Description: ribosomal assembly complex component Ipi3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.1e-07   32.4   2.2    0.00013   22.7   0.1    4.2  4  WD40         WD domain, G-beta repeat
     0.0033   17.7   0.0        3.3    8.1   0.0    3.3  4  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
  ------ inclusion threshold ------
      0.027   14.5   0.0      0.067   13.2   0.0    1.6  1  Gryzun-like  Gryzun, putative Golgi trafficking
      0.062   13.8   5.9        1.5    9.4   0.5    3.6  4  PQQ_3        PQQ-like domain
      0.071   12.7   2.1       0.44   10.1   0.7    2.4  2  PQQ_2        PQQ-like domain
       0.43   10.8   6.2       0.73   10.1   6.2    1.3  1  TMF_TATA_bd  TATA element modulatory factor 1 TATA binding
          1    9.6   7.6        1.7    8.8   7.6    1.4  1  CENP-Q       CENP-Q, a CENPA-CAD centromere complex subunit
        1.4    8.2   8.5        2.2    7.6   8.5    1.2  1  DUF4407      Domain of unknown function (DUF4407)


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0       3.2   7.1e+03      13      34 ..      89     102 ..      56     105 .. 0.67
   2 !   22.7   0.1   5.6e-08   0.00013       3      38 .]     122     158 ..     120     158 .. 0.90
   3 ?    2.8   0.0      0.11   2.5e+02       2      18 ..     180     198 ..     179     220 .. 0.67
   4 ?    3.4   0.0     0.069   1.5e+02      14      38 .]     301     325 ..     291     325 .. 0.91

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 3.2
                 EEEEEEETTSSEEEEEETTSEE CS
        WD40  13 vtslafspdgawlasGsdDgtv 34 
                 ++sl         ++G+ +g v
  EEA19555.1  89 IRSL--------AVTGGQNGEV 102
                 6777........7788877766 PP

  == domain 2  score: 22.7 bits;  conditional E-value: 5.6e-08
                 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 ++ t   H ++vtsl ++p +++++sGs D +v++W+
  EEA19555.1 122 QVSTTPSHlQPVTSLVVDPTSNFILSGSADANVHVWS 158
                 5667789*****************************5 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.11
                 EEEEEEESS.SSEEEEE.E CS
        WD40   2 qclrtltGH.ssvtsla.f 18 
                 +++rt+  H + +t+la  
  EEA19555.1 180 SPIRTFGNHrTAITALAvG 198
                 6899*****999****752 PP

  == domain 4  score: 3.4 bits;  conditional E-value: 0.069
                 EEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  14 tslafspdgawlasGsdDgtvriWd 38 
                 tsla s dg  l sG+ +g+v  Wd
  EEA19555.1 301 TSLALSYDGMTLYSGHPNGSVLAWD 325
                 89999***********9****9998 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.0     0.014        32      40      86 ..      88     135 ..      58     138 .. 0.76
   2 ?    4.3   0.0     0.023        51      49      86 ..      99     135 ..      97     173 .. 0.60
   3 ?   -1.7   0.0       1.7   3.7e+03      50      65 ..     192     207 ..     155     225 .. 0.65
   4 !    8.1   0.0    0.0015       3.3      24      77 ..     284     336 ..     274     347 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.014
  ANAPC4_WD40  40 evrsLaWk..pdgklLavaysdgevrlldaesgkvvhslsvksekavtc 86 
                  ++rsLa    ++g++L+ +++ g++ l +  +g+ v++ + + +  vt+
   EEA19555.1  88 RIRSLAVTggQNGEVLVLGTEGGRLILWETCTGRQVSTTPSHLQP-VTS 135
                  556555542279************************999888663.655 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.023
  ANAPC4_WD40  49 dgklLavaysdgevrlldaesgkvvhslsvksekavtc 86 
                  +g++L+ +++ g++ l +  +g+ v++ + + +  vt+
   EEA19555.1  99 NGEVLVLGTEGGRLILWETCTGRQVSTTPSHLQP-VTS 135
                  5555555555555555555555555555554442.333 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 1.7
  ANAPC4_WD40  50 gklLavaysdgevrll 65 
                   + Lav++  g+ ++ 
   EEA19555.1 192 ITALAVGHGTGRSNIA 207
                  4678888888865553 PP

  == domain 4  score: 8.1 bits;  conditional E-value: 0.0015
  ANAPC4_WD40  24 lngqrvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhsls 77 
                  ln  + w +  +++++  +sLa + dg  L  ++ +g+v   d+  +k   ++ 
   EEA19555.1 284 LNADQQWAV-PSADKGAATSLALSYDGMTLYSGHPNGSVLAWDVARTKFSTTIA 336
                  677888999.7889999**************************99998877664 PP

>> Gryzun-like  Gryzun, putative Golgi trafficking
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0     3e-05     0.067       9      31 ..     136     158 ..     126     161 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 3e-05
  Gryzun-like   9 ilVeesdnFfvsGlkkvnlrilr 31 
                  ++V++++nF++sG    n+++++
   EEA19555.1 136 LVVDPTSNFILSGSADANVHVWS 158
                  78********************7 PP

>> PQQ_3  PQQ-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.1     0.018        40       7      33 ..      83     112 ..      82     117 .. 0.81
   2 ?   -1.6   0.0       1.9   4.2e+03       3      20 ..     113     139 ..     110     156 .. 0.62
   3 ?   -0.8   0.0       1.1   2.4e+03       3      30 ..     217     254 ..     216     260 .. 0.54
   4 ?    9.4   0.5   0.00069       1.5       3      38 ..     288     326 ..     287     329 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.018
       PQQ_3   7 vqlpgpvnsspavdgg....lvyvgtgdGtl 33 
                 v++p+++ +s+av gg    +++ gt+ G+l
  EEA19555.1  83 VPFPERI-RSLAVTGGqngeVLVLGTEGGRL 112
                 7899999.7888887756668******9998 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 1.9
       PQQ_3   3 vlWsv.......qlpg...pvnsspavd 20 
                 +lW++       ++p+   pv +s++vd
  EEA19555.1 113 ILWETctgrqvsTTPShlqPV-TSLVVD 139
                 579988877776667766455.556666 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 1.1
       PQQ_3   3 vlWsvqlpgpvnssp.........avd..gglvyvgtgd 30 
                 v W+++++ ++ ++          +vd  ++  yvg + 
  EEA19555.1 217 VAWEYTTG-RILRTFllpsvaisiTVDavDRACYVGYES 254
                 67999888.555544455554443222335555555555 PP

  == domain 4  score: 9.4 bits;  conditional E-value: 0.00069
       PQQ_3   3 vlWsvqlpg.pvnsspavd.gg.lvyvgtgdGtlyAlDa 38 
                 ++W+v+  +  + +s+a++ +g ++y g ++G++ A D 
  EEA19555.1 288 QQWAVPSADkGAATSLALSyDGmTLYSGHPNGSVLAWDV 326
                 789998877566688866536668*************95 PP

>> PQQ_2  PQQ-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.7   0.00019      0.44     118     236 ..      92     229 ..      58     230 .. 0.68
   2 ?    1.7   0.4     0.071   1.6e+02     114     190 ..     301     326 ..     198     347 .. 0.51

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00019
       PQQ_2 118 pava....gdtvvvgessgklvaldpkdGkvlWerelaaprgtselsrvgdisgrpvvaeg...tVyassgqgrllal..dlatgrrl.wskeiss... 203
                  av+    g+++v+g+++g+l      +G+++  +++  ++ ts    v+d+++  ++++    +V + s ++ ll++   ++tg+ +     ++s   
  EEA19555.1  92 LAVTggqnGEVLVLGTEGGRLILWETCTGRQVSTTPSHLQPVTS---LVVDPTSNFILSGSadaNVHVWSIPQ-LLSFsqPASTGQDQkA---PNSpir 183
                 23336778999999999999999999999999999998888777...79999999999955668999999999.6666567777773323...444444 PP

       PQQ_2 204 ............inglpildgdllyvvsa..gelialdratGavlWk 236
                              +g +     ++ +++a  ++ +a+++ tG++l++
  EEA19555.1 184 tfgnhrtaitalAVG-HGTGRSNIAISTAqdSTAVAWEYTTGRILRT 229
                 466666664433222.1111223444442689999999999998765 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.071
       PQQ_2 114 ssaspavagdtvvvgessgklvaldpkdGkvlWerelaaprgtselsrvgdisgrpvvaegtVyassgqgrllaldl 190
                 +s + +++g t++ g+++g + a d                                                   +
  EEA19555.1 301 TSLALSYDGMTLYSGHPNGSVLAWD---------------------------------------------------V 326
                 2233333344444444444444444...................................................3 PP

>> TMF_TATA_bd  TATA element modulatory factor 1 TATA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   6.2   0.00033      0.73       3      77 ..     442     516 ..     440     524 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00033
  TMF_TATA_bd   3 stssagpsvqlverlsseirrlEgElaslkeelerleaerdeareeivklmkeneelkelkkeleelekeleelq 77 
                  +ts+ ++++ +    ss+i  ++ E+++lk++l+  ea r++ ++e +kl ++  +l+e++++ ++l++++++l+
   EEA19555.1 442 TTSNGHSTTATTAVESSQIIAMQEEITNLKKQLSINEAARRADADENMKLKTNIRDLQESNNRFQSLQAKYDKLK 516
                  45556666666666689*****************************************************99986 PP

>> CENP-Q  CENP-Q, a CENPA-CAD centromere complex subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   7.6   0.00075       1.7      29     134 ..     448     560 ..     417     563 .] 0.76

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00075
      CENP-Q  29 klldekaaleaqLspelhslelLeaeiekeeralerdyeaLreLeknakaearerke......klkkehvllqesdseelslleassdevlgea..sgt 119
                 +++  +a +++q  ++++ +  L+++++  e+a   d  +  +L++n++++++++++      k  k+ v+++ +++e+++l+  +  + +++a  +g 
  EEA19555.1 448 STTATTAVESSQIIAMQEEITNLKKQLSINEAARRADADENMKLKTNIRDLQESNNRfqslqaKYDKLKVVAR-AEKEDRDLERRKAWFENEKAgtNGD 545
                 56667788999*******************************************7777877544445555555.6666666666666655555566444 PP

      CENP-Q 120 vfsdlepeldeellp 134
                 v    + ++de+l +
  EEA19555.1 546 VALRQARATDEDLDE 560
                 444455555665555 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   8.5   0.00096       2.2     126     235 ..     440     555 ..     407     560 .. 0.78

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.00096
     DUF4407 126 qlaaa....ltaelaeleaqiaalqaeidaaearldalraeaqkeldgtk..gtgttgvaGkgpaakekkaqldaaqaelaelkakldatarlaalrae 218
                 +++++     ta++a + +qi a+q+ei++++++l+ ++a+ ++ +d +   +t +   +    ++++ +a++d+++    + k+++d + r a  ++e
  EEA19555.1 440 EVTTSnghsTTATTAVESSQIIAMQEEITNLKKQLSINEAARRADADENMklKTNIRDLQESNNRFQSLQAKYDKLKVVARAEKEDRDLERRKAWFENE 538
                 3333346778999999*****************99988888888888777779999999999999************9999999999999999999999 PP

     DUF4407 219 laeleaerakeraasqa 235
                 +a+ + + a ++a+ ++
  EEA19555.1 539 KAGTNGDVALRQARATD 555
                 99999888888887766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (563 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       885  (0.0493614); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.44
# Mc/sec: 3858.82
//
Query:       EEA19556.1  [L=708]
Description: hypothetical protein PMAA_003440 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (708 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       469  (0.0261587); expected 358.6 (0.02)
Passed bias filter:                      300  (0.0167327); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.80u 0.33s 00:00:01.13 Elapsed: 00:00:00.59
# Mc/sec: 3612.25
//
Query:       EEA19557.1  [L=425]
Description: lipoic acid synthetase precursor [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.1e-23   82.8   0.0    4.3e-23   81.8   0.0    1.5  1  LIAS_N       N-terminal domain of lipoyl synthase of Radical_
      4e-15   56.6   0.0    6.2e-15   56.0   0.0    1.3  1  Radical_SAM  Radical SAM superfamily


Domain annotation for each model (and alignments):
>> LIAS_N  N-terminal domain of lipoyl synthase of Radical_SAM family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.8   0.0   4.8e-27   4.3e-23      21     108 .]      49     147 ..      23     147 .. 0.79

  Alignments for each domain:
  == domain 1  score: 81.8 bits;  conditional E-value: 4.8e-27
      LIAS_N  21 aastsssltdekkelleeGPdlqDFvsgdkedk......seweeyk.....gnlkrekgerlrLPswlktkiPlGknynkikndlreLnLhtvCeeaRC 108
                 ++ ++ ++t ++k+ l+ GP++ DFvsg+ + +      se++ ++     g + r k+e+ rLPswlkt iP  +ny++ik+dlr+L+L+tvCeeaRC
  EEA19557.1  49 STLPKRRKTTTFKDKLNAGPSFADFVSGNGDSNnapldaSEAYALEtvmipGPAGRGKKEHTRLPSWLKTPIPDSTNYKRIKKDLRGLKLNTVCEEARC 147
                 44455678899****************8766554677665555554212225567888899************************************** PP

>> Radical_SAM  Radical SAM superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.0   0.0     7e-19   6.2e-15       5     165 ..     171     330 ..     167     332 .. 0.88

  Alignments for each domain:
  == domain 1  score: 56.0 bits;  conditional E-value: 7e-19
                  SEESS--TTTSCCTTHHHHHHHHHHHHHHHHHHHHHHHHHTTSEEEEEESSTGGGS.....TTHHHHHHHHHHTCCCTEEEEEEECSSCHGHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Radical_SAM   5 rgCnlrCsfCarpetvrregrgrslsveeileevkelkaekgvkevilgggeplly.....pdfvellerlaklavpgiritvetngtlpdeeklerl 97 
                    C+++C+fC+++    + +++  l++ e ++ +++l  ++g ++v+l++ + ++       +f+e + +++++  pgi + + t  +  d +++++ 
   EEA19557.1 171 DSCTRGCRFCSVK----TLRTPGPLDPHEPENTAEAL-SRWGLGYVVLTSVDRDDLsdggaHHFAETVIKIKQK-APGILVECLTGDFAGDFDMVALV 262
                  56***********....59******************.599999999999999999455555555555555555.6********************** PP

                  HHTT-SEEEEEEBSSSHHHHHHHHT.CTSHHHHHHHHHHHHHHTTSET..EEEEEEEBTTTSHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxx RF
  Radical_SAM  98 lelgvdrvslgleaaddekvlklmn.rghtfeevlealeklreagikr..vvdrivglpGendeeleelle 165
                  ++ g+d++++++e++       +++ r+ tf++ l++le++++a  ++  +++ ++++ Ge+++++++ l+
   EEA19557.1 263 AKSGLDVYAHNVETVEA--LTPHVRdRRATFQQSLRVLEAAKRA-KPSliTKTSMMLGFGETEDQMWDALR 330
                  ***************99..566777799****************.899******************99887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (425 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       598  (0.0333538); expected 358.6 (0.02)
Passed bias filter:                      507  (0.0282782); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 2706.30
//
Query:       EEA19558.1  [L=469]
Description: phosphoserine phosphatase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.7e-26   91.5   0.0    1.2e-25   91.0   0.0    1.2  1  HAD              haloacid dehalogenase-like hydrolase
    3.5e-19   69.9   0.6    5.5e-19   69.3   0.6    1.3  1  Hydrolase        haloacid dehalogenase-like hydrolase
      4e-10   39.9   0.0    1.2e-08   35.0   0.0    2.7  3  Hydrolase_3      haloacid dehalogenase-like hydrolase
    5.3e-06   26.6   0.1    3.8e-05   23.9   0.1    2.3  1  HAD_2            Haloacid dehalogenase-like hydrolase
    0.00035   20.0   0.0     0.0019   17.6   0.0    1.9  1  Put_Phosphatase  Putative Phosphatase
  ------ inclusion threshold ------
       0.13   11.7   0.3        3.3    7.1   0.1    2.1  2  DUF4392          Domain of unknown function (DUF4392)


Domain annotation for each model (and alignments):
>> HAD  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.0   0.0   4.1e-29   1.2e-25       1     187 [.     247     418 ..     247     419 .. 0.84

  Alignments for each domain:
  == domain 1  score: 91.0 bits;  conditional E-value: 4.1e-29
         HAD   1 alfDfDgTLldgdslelllrfllrrgaprlwralreklllalfrellrldraglaelleallaglseelaaelerfvaevirpklldpgalellaahra 99 
                 a+fD+D TL+++++++++++f++ ++      ++ + ++ a+    ++ld  +  ++  +ll+g ++++ + l+++v       ++ pga+el++a +a
  EEA19558.1 247 AIFDMDSTLIQNETIDEIAKFVGVEK------EVSAITERAM---NGELDFTASLKARVSLLKGVPADVFDKLQHIV-------TISPGARELCKALKA 329
                 79******************555443......4444444444...3333334555999*******************.......999************ PP

         HAD 100 aGdrvvvvSgglrplvepllaelgadevlatelevdd...rltgelglegkpvrg.egkvaalrewlaaegegidleevvayGDspsDlpll 187
                  G++ +v+Sgg++pl+  l++elg+d+  a++l+vd+    ltge  +egkp+ + ++k + lr+   a+ ++i++  ++a+GD+ +Dlp+l
  EEA19558.1 330 LGYKMAVLSGGFQPLADWLANELGIDYAFANHLAVDEttqTLTGE-LVEGKPIIDaAQKRTLLRK--IAADNNIPITQTIAIGDGANDLPML 418
                 *********************************************.6666666664788888888..66777788888*************9 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.3   0.6   1.8e-22   5.5e-19       3     209 ..     246     421 ..     244     422 .. 0.87

  Alignments for each domain:
  == domain 1  score: 69.3 bits;  conditional E-value: 1.8e-22
                 EEEEESBTTTBCHHHHHHHHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHETTTEHHHHTHHHHHHHHHCHHHHHHHHHHHHHHCHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase   3 tvvfDkdGTLttgepsvedvivsaalalaaaletgsehpigkalvaaakarsgaltgfatfigrgayaigkpewltaldippdlgaaigsaqsqgrtva 101
                 + +fD+d TL++ e     +i+++                     a++ +++ +++ +++     +++ g+ +++++l               ++r + 
  EEA19558.1 246 LAIFDMDSTLIQNE-----TIDEI---------------------AKFVGVEKEVSAITE-----RAMNGELDFTASL---------------KARVSL 298
                 679***********.....*****.....................***************.....*************...............666666 PP

                 HHTTHHHHHHHHHHTHHBHTTHHHHHHHHHHTTEEEEEEESSEHHHHHHHHHHTT.GGGESEEEEHHCES........STTT..SHHHHHHHHHHHT.. CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxx........xxxx..xxxxxxxxxxxxx.. RF
   Hydrolase 102 llqaralavftiadplkvkpeaaeavasLkaagievvlltgdnpetaeraanqlG.ddyfdaviasdiet........vakp..spegkvaaireLq.. 187
                 l+   a+   ++++  ++ p+a+e++++Lka g+++++l+g+++  a+ +an+lG d +f++++a+d++t         +kp  +  +k+ ++r++   
  EEA19558.1 299 LKGVPADVFDKLQHIVTISPGARELCKALKALGYKMAVLSGGFQPLADWLANELGiDYAFANHLAVDETTqtltgelvEGKPiiDAAQKRTLLRKIAad 397
                 66333333334446666789***********************************98888999999999999999998888899999999999999655 PP

                 ..STGGGEEEEESSHHHHHHHHHT CS
                 ..xxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase 188 ..gkpeevamVGDgvnDaaalaaA 209
                   +++ +++++GDg+nD+++l +A
  EEA19558.1 398 nnIPITQTIAIGDGANDLPMLHEA 421
                 5699*****************998 PP

>> Hydrolase_3  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0      0.12   3.5e+02       2      20 ..     248     260 ..     247     298 .. 0.67
   2 ?   -0.4   0.0      0.27     8e+02      15      55 ..     315     355 ..     310     371 .. 0.84
   3 !   35.0   0.0   4.1e-12   1.2e-08     186     229 ..     385     428 ..     381     438 .. 0.91

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.12
                  EEEIIIIIS-TTS---HHH CS
  Hydrolase_3   2 alDlDGTLlnsdkkisekt 20 
                  ++D+D TL+++      +t
   EEA19558.1 248 IFDMDSTLIQN------ET 260
                  69999999654......34 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.27
                  ---HHHHHHHHHHHHTTSEEEEE-SS-HHHHHHHHHHCCCC CS
  Hydrolase_3  15 kisektkeaikklkekgikvviATGRslravlpvleelgld 55 
                  +is+ ++e +k lk+ g+k ++ +G     +  +++elg+d
   EEA19558.1 315 TISPGARELCKALKALGYKMAVLSGGFQPLADWLANELGID 355
                  79999*****************9998888888888888887 PP

  == domain 3  score: 35.0 bits;  conditional E-value: 4.1e-12
                  -SHHHHHHHHHHHCT--GGGEEEEESSGGGHHHHHHSSEEEEET CS
  Hydrolase_3 186 vsKgtalkklakelnisleeviafGDgeNDieMLeaaglgvAmg 229
                  ++K t l+k+a   ni+  ++ia+GDg ND++ML  a+lgvA +
   EEA19558.1 385 AQKRTLLRKIAADNNIPITQTIAIGDGANDLPMLHEAELGVAWR 428
                  789**************************************965 PP

>> HAD_2  Haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.1   1.3e-08   3.8e-05       2     177 ..     248     427 ..     247     428 .. 0.75

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 1.3e-08
       HAD_2   2 iFDlDgTlldteeliiqafnelleeyglselseeelrkliglslrellrklgeseeeeekieellrkyneekkkkevkpydgvkelLeeLkeagyklgi 100
                 iFD+D Tl+   e+i ++++ +  e ++s ++e  ++  + ++       l+ +     +++ +  ++ +++++  v++ +g++el + Lk+ gyk+++
  EEA19558.1 248 IFDMDSTLIQN-ETIDEIAKFVGVEKEVSAITERAMNGELDFTA-----SLKARVS---LLKGVPADVFDKLQH-IVTISPGARELCKALKALGYKMAV 336
                 89999999965.55667777777777776666666666666665.....3333222...666666666666676.9*********************** PP

       HAD_2 101 vTsksreaveekleqlgiesyFdvivtsedvekk........KPdpeviek..alekl....klkkeeviyvGDsptDieaakkagikvia 177
                  + + +  ++   ++lgi+  F   +  +++++         KP  +  +k  +l+k     ++   ++i +GD  +D+   ++a + v++
  EEA19558.1 337 LSGGFQPLADWLANELGIDYAFANHLAVDETTQTltgelvegKPIIDAAQKrtLLRKIaadnNIPITQTIAIGDGANDLPMLHEAELGVAW 427
                 **********************998888888777677788889976655432234444444488889***********9999999887766 PP

>> Put_Phosphatase  Putative Phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   6.3e-07    0.0019       2     182 ..     246     415 ..     245     431 .. 0.77

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 6.3e-07
  Put_Phosphatase   2 lvvfDFDktiidedsdnwvvdelpatelfeelretlrkglwnelmdrvlkelhe.qgvseadikkvlrsiplspglvelikslakkkleldlii 94 
                      l++fD D t+i++++ + + + ++ +++ + + e   +g   ++ + + +++   +gv  + + k  + +++spg  el k+l  k+l++ + +
       EEA19558.1 246 LAIFDMDSTLIQNETIDEIAKFVGVEKEVSAITERAMNGE-LDFTASLKARVSLlKGVPADVFDKLQHIVTISPGARELCKAL--KALGYKMAV 336
                      789*****************************99988664.445555555554415677777777777889************..799****** PP

  Put_Phosphatase  95 iSDaNsffieeileaagledlFseiftNPaavdasGeltvlpyhehsCklcpsNlCKgkvleelvaeqaregveyerliYvGDganDl 182
                      +S   +   +++ + +g+   F+    N  avd++ +       e +         K+++l ++ a+   +++  ++ i +GDganDl
       EEA19558.1 337 LSGGFQPLADWLANELGIDYAFA----NHLAVDETTQTLTGELVEGKPI--IDAAQKRTLLRKIAAD---NNIPITQTIAIGDGANDL 415
                      ****9999999999999998875....5566666665555555554433..2333488888888888...467788999999999997 PP

>> DUF4392  Domain of unknown function (DUF4392)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0      0.03        89      59      79 ..     318     338 ..     317     372 .. 0.87
   2 ?    7.1   0.1    0.0011       3.3     177     195 ..     398     417 ..     383     422 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.03
     DUF4392  59 lGAialaraLqalgkkvvivt 79 
                 +GA  l++aL+alg+k  ++ 
  EEA19558.1 318 PGARELCKALKALGYKMAVLS 338
                 8**************988775 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0011
     DUF4392 177 keig.iptigiGDgGNElGm 195
                 ++i+ ++ti+iGDg N+l m
  EEA19558.1 398 NNIPiTQTIAIGDGANDLPM 417
                 5677899**********998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (469 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       396  (0.0220871); expected 358.6 (0.02)
Passed bias filter:                      385  (0.0214736); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.46
# Mc/sec: 3063.80
//
Query:       EEA19559.1  [L=305]
Description: 3'-phosphoadenosine-5'-phosphosulfate reductase Met16, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.6e-45  155.3   0.0    2.1e-44  151.6   0.0    2.0  2  PAPS_reduct  Phosphoadenosine phosphosulfate reductase family


Domain annotation for each model (and alignments):
>> PAPS_reduct  Phosphoadenosine phosphosulfate reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  151.6   0.0   1.2e-48   2.1e-44       3     174 .]      69     246 ..      67     246 .. 0.97
   2 ?    1.5   0.0     0.015   2.6e+02      72      99 ..     269     299 ..     254     303 .. 0.81

  Alignments for each domain:
  == domain 1  score: 151.6 bits;  conditional E-value: 1.2e-48
                  EEE--SSCTCHHHHHHHHHHCTTH....EEEEEE-STB-HHHHHHHHHHHHHT.T-EEEEEE-SCHHHHHHHHHH-S-THHHC...HHHHHHTHHHHH CS
  PAPS_reduct   3 vvsvsgGkdslVllhLalkafkpv....pvvfvdtghefpetiefvdeleery.glrlkvyepeeevaekinaekhgsslyee...aaeriaKveplk 92 
                   +++++G  +l++ ++++k ++p+     ++f+dt h+f+et+ +vd++++ry +l+++vy+p   ++e++ a+k+g++l+e+   +++ +aKvep++
   EEA19559.1  69 YQTTAFGLTGLAITDMLSKLNVPRpqvvDLIFLDTLHHFKETLSLVDRVRQRYpNLNIHVYKPLGAETEEEFANKYGERLWETndeRYDWLAKVEPAQ 166
                  57899******************7666689******************************************************************** PP

                  HHHHCTTECEEE----CCCTTTTTTSSSEEECTTT-SCEEE-CCCT--HHHHHHHHHHCT--B-CCCCTT-SS--BCTTB-S CS
  PAPS_reduct  93 kaLekldedalltGaRrdesksraklpiveidedfekslrvfPllnWteedvwqyilrenipynpLydqgfrsiGcvpctga 174
                  +a+++l+ da+ltG Rr++  +r  l ++eide+    ++v+Pl+nWt e+v qy++ +++pyn+L d+g++siG++++t++
   EEA19559.1 167 RAYRDLKVDAVLTGRRRSQGGKRGDLDVLEIDEA--GLIKVNPLANWTFEQVRQYVKDNGVPYNELLDRGYKSIGDYHSTKP 246
                  **********************************..79*****************************************986 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.015
                  H-S-THHHC...HHHHHHTHHHHHHHHHCTT CS
  PAPS_reduct  72 khgsslyee...aaeriaKveplkkaLekld 99 
                    + s+y +   ++er ++ e+l++aLe+++
   EEA19559.1 269 HNPRSKYAQyllEMERKRQEEALTQALENVQ 299
                  4578889889999**************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (305 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       586  (0.0326845); expected 358.6 (0.02)
Passed bias filter:                      465  (0.0259356); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.48
# Mc/sec: 1901.90
//
Query:       EEA19560.1  [L=491]
Description: monoxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.8e-11   42.8   3.2    9.4e-10   38.3   3.2    2.7  1  FAD_binding_3  FAD binding domain
    0.00035   20.3   0.2      0.004   16.8   0.1    2.2  2  DAO            FAD dependent oxidoreductase
  ------ inclusion threshold ------
      0.013   14.7   0.0       0.79    8.9   0.0    2.2  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
      0.033   14.4   0.0      0.092   13.0   0.0    1.8  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
       0.13   12.5   0.0       0.35   11.0   0.0    1.8  2  NAD_binding_2  NAD binding domain of 6-phosphogluconate dehyd


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.3   3.2   2.6e-13   9.4e-10       5     320 ..      54     387 ..      51     397 .. 0.61

  Alignments for each domain:
  == domain 1  score: 38.3 bits;  conditional E-value: 2.6e-13
                    EEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSSS--EEEHHHHHHHHHT..T-HHHHHHHSEECCCCEEEEEEECCCC........CEEEEEH CS
  FAD_binding_3   5 lIVGaGpaGlmlallLseaGvrvvlvekrsttvvlpradglnqrtmellrql..Gledrilaegapnelmgealynelsdt........pkaradl 90 
                     I+G+G  Gl lal L ++ +  ++ e+ ++  + + + g++    e + +l   + + +++ g +++ + + + ++  +t        ++ + d+
     EEA19560.1  54 SIIGSGIIGLNLALGLLQRNIPITIYEQAQELKEIGTGIGFSANLEECITELdpRISAVLHKIGLRQHQSLQWVVAS--NTeedfslrgKDEMFDM 147
                    57777777777777666666777777777777777766666666666665543345555555555554433333333..11223344345666666 PP

                    HCHHCST-CEE--HHHHHHHHHHHHHHHT.EEETCSEEEECCEECCCCCCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHHHTGG..EEEEEEEE CS
  FAD_binding_3  91 elesspervtvypqteleriLvehaeerg.lqvrfktevesleqdeegvtaevrdketgeeetvrakYlvGaDGgrStvrktlgie..fegeetvy 183
                      +s  +   ++   el + Lv+     +   +r ++++e++eq  ++ + ++    +g++  ++ + ++G+DG +S+vr  l  +    g  +  
     EEA19560.1 148 G-LSLTKGFWLCHRAELVNELVKL---LPvGCLRLGKRLEGVEQKSDTGKVVMSFM-DGKK--IETDAVIGCDGIKSRVRYLLAGDnnPAGIPHYA 236
                    6.4455555566666666666665...44445677889999999999877777776.5665..99999************9886653233434444 PP

                    EEEEEEEEEEC.-SCCCTTC.....CEEEEECCTTEEEEEECCETEEEEEEEE.ECCE-GGGS......CCCHHHHHHHHHHHHH..HTTSSCEEE CS
  FAD_binding_3 184 eagvldvlfda.dlsdivep.....lvlilsaesrgvmviPlentlerfyvqv.earaekeer......sekfteeevkarlrei..vgektldve 264
                    +      l++  ++s i  +       +i++  +      P +n  +rf  ++  +r++ + +      + + +++e+++   +   +    +++ 
     EEA19560.1 237 NESAYRCLVEMhKVSPILGNyasvmTLWIGHGANL--VTYPISN--NRFFNVAaFVRDNTGYWpdyskqTVQASKAEIIDSFSSFnpMLRRLIEAL 328
                    45556666666677766666777554455544444..5777777..34444440444444444332111223333333333322211223456667 PP

                    EEEEEEEEEEEEE...ESSSEETTEEE-GGGTEEE-STTSHHHHHHHHHHHHHHHHHHH CS
  FAD_binding_3 265 ieevsawtvaqrv...aekyrkgrvflaGDAaHihpPtgGqGlNtaiqDavnLawkLaa 320
                    ++e ++w++ + +    ++y +g v +aGDAaH+ +P +G+G  ++i+Da+ L++ L +
     EEA19560.1 329 PDEQNRWGMFDTLdhpLDSYVEGCVAVAGDAAHASTPHHGMGAGMGIEDAIVLVTVLEK 387
                    77888888876653337899********************************9998865 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.1   1.1e-06     0.004       2      33 ..      53      86 ..      52     100 .. 0.87
   2 ?    1.0   0.0     0.068   2.4e+02     132     210 ..     146     226 ..     102     375 .. 0.53

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 1.1e-06
                EEEECTSHHHHHHHHHHHHTT..EEEEESSSSTT CS
         DAO  2 vviiGGGiiGlstAyeLarrg..Vtllekgdiag 33
                + iiG+GiiGl  A+ L +r+  +t++e++ ++ 
  EEA19560.1 53 ISIIGSGIIGLNLALGLLQRNipITIYEQAQELK 86
                66******************889*****997765 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.068
                 SEEEEETTEEEE.EHHHHHHHHHHHHHHTT-EEEESECEEEEEEEETCEEEEE...EECTEEEEEEEEEEE--GGGHH...HHHTT CS
         DAO 132 lgalfypdtgqv.dpakltaalaraaealGveilegtevtgleeedgkvwgve...rttpgendaadavVnaaGawsd...llgll 210
                   +l  + + ++ + a+l++ l + +    + +++g + +g+e++++ ++ v    +   g + + dav+ + G+ s+   ll+++
  EEA19560.1 146 DMGLSLTKGFWLcHRAELVNELVKLLP--VGCLRLGKRLEGVEQKSDTGKVVMsfmD---GKKIETDAVIGCDGIKSRvryLLAGD 226
                 455665555666677888888877764..2478888888888775533233324454...54433488999999998866433333 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.0   0.00022      0.79       3      32 ..      53      82 ..      34     142 .. 0.79
   2 ?    3.4   0.0      0.01        36     201     240 ..     177     218 ..     175     229 .. 0.84

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00022
                 EEEE--SHHHHHHHHHHHHHTS-EEEEETT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  3 vvviGgGpAGlaaaltlaqagakvtlvele 32
                 + +iG+G+ Gl++al l q ++ +t++e+ 
   EEA19560.1 53 ISIIGSGIIGLNLALGLLQRNIPITIYEQA 82
                 668888888888888888888888888632 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.01
                  EESCEEEEEEETTE..EEEEEETTSCEEEESEEEE-S-EEES CS
                  xxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 201 klgtsvkeidgnge..klevvledgeeidadlvvvavGvrps 240
                  +lg++ + ++++++  k+ +   dg++i++d v+ + G++ +
   EEA19560.1 177 RLGKRLEGVEQKSDtgKVVMSFMDGKKIETDAVIGCDGIKSR 218
                  6777888888888877788*****************999865 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   2.6e-05     0.092       1      30 [.      55      84 ..      55     111 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 2.6e-05
                   EE--SHHHHHHHHHHHCCTEEEEEE-SSSS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekrdr 30
                   I+G+G+ Gl +A  L ++++ ++++e+++ 
     EEA19560.1 55 IIGSGIIGLNLALGLLQRNIPITIYEQAQE 84
                   9*************************9875 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   9.8e-05      0.35       2      57 ..      53     106 ..      52     125 .. 0.77
   2 ?   -2.7   0.0       1.7   6.1e+03     139     158 .]     247     266 ..     246     266 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 9.8e-05
                    EEEE--SHHHHHHHHHHHHTT-EEEEE-SSHHHHHHHHHTTEEE-SSHHHHHHHCS CS
  NAD_binding_2   2 igfiGlGvMGsnmalnllkagykvavynrtkekveelvaegakaaesieelvasld 57 
                    i +iG G++G n+al ll++++ +++y+  +e ++e + +g+   +++ee++++ld
     EEA19560.1  53 ISIIGSGIIGLNLALGLLQRNIPITIYEQAQE-LKE-IGTGIGFSANLEECITELD 106
                    899************************96643.333.3456777777777777764 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 1.7
                    HHHHHHHHHHHEEEEEEE-E CS
  NAD_binding_2 139 fervkpvleaigakvthviG 158
                    +++v+p+l ++++ +t +iG
     EEA19560.1 247 MHKVSPILGNYASVMTLWIG 266
                    57899********9999988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (491 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       566  (0.031569); expected 358.6 (0.02)
Passed bias filter:                      491  (0.0273858); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.41
# Mc/sec: 3567.59
//
Query:       EEA19561.1  [L=736]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
     0.0015   18.8   3.3       0.07   13.4   0.3    2.6  2  zf-Di19    Drought induced 19 protein (Di19), zinc-binding
     0.0028   16.8   0.1     0.0045   16.1   0.1    1.4  1  Clusterin  Clusterin
  ------ inclusion threshold ------
      0.048   14.1   4.9        1.6    9.3   0.1    3.1  2  zf-H2C2_2  Zinc-finger double domain
        0.2   12.4   1.5       0.63   10.8   1.5    1.8  1  PMC2NT     PMC2NT (NUC016) domain


Domain annotation for each model (and alignments):
>> zf-Di19  Drought induced 19 protein (Di19), zinc-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.3   0.2    0.0052        23       3      10 ..     275     282 ..     273     297 .. 0.79
   2 !   13.4   0.3   1.6e-05      0.07      19      49 ..     325     357 ..     317     362 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0052
     zf-Di19   3 ftCPyCgk 10 
                 f CPyC +
  EEA19561.1 275 FECPYCFH 282
                 99****87 PP

  == domain 2  score: 13.4 bits;  conditional E-value: 1.6e-05
     zf-Di19  19 eHvedeHrveskevvCPvCaekvtk..dlvaHl 49 
                  H+ + Hr+ ++   CP+C +++++   + +H+
  EEA19561.1 325 FHMREAHRQGQNGLACPLCHAEIQAlsSFEKHV 357
                 6******************99887655777776 PP

>> Clusterin  Clusterin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.1     1e-06    0.0045     113     177 ..      84     146 ..      60     217 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 1e-06
   Clusterin 113 eflnkispfsfwlneeridsllvseedeeedaeleqledsfsqlssdvdslfnrslkvfkqmqqe 177
                 ++++ ++++    ++++++ l+++ ed+ e+++++++++ +++++++++slf+ s+++ +++++ 
  EEA19561.1  84 HIFQDVAEV--INENDDEEALEIEIEDDDETKDMTEVQQLYQSIADTINSLFQISMAIRRPADHD 146
                 445544444..34456677788889999******************************9999873 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   1.2    0.0094        42      13      20 ..     273     280 ..     265     281 .. 0.87
   2 ?    9.3   0.1   0.00037       1.6       5      21 ..     326     344 ..     322     346 .. 0.93

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0094
   zf-H2C2_2  13 kpyeCplC 20 
                 +p+eCp+C
  EEA19561.1 273 SPFECPYC 280
                 59****** PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.00037
   zf-H2C2_2   5 Hirk.Ht.gekpyeCplCd 21 
                 H+r+ H+ g++ + CplC+
  EEA19561.1 326 HMREaHRqGQNGLACPLCH 344
                 *******99999******8 PP

>> PMC2NT  PMC2NT (NUC016) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   1.5   0.00014      0.63      23      80 ..      69     133 ..      56     136 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00014
      PMC2NT  23 pefaksldeqserllslinsllklaaskseisas.......sklededdveekfksvvdvvDsll 80 
                 + ++++ ++  +rll++ +++++ ++++++ +a        ++ +d+ +v++ ++s+ d++ sl+
  EEA19561.1  69 SHLREETTRLLSRLLHIFQDVAEVINENDDEEALeieieddDETKDMTEVQQLYQSIADTINSLF 133
                 678999999999*****************99877999999888899999************9997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (736 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       726  (0.0404931); expected 358.6 (0.02)
Passed bias filter:                      548  (0.030565); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.72u 0.31s 00:00:01.03 Elapsed: 00:00:00.51
# Mc/sec: 4312.00
//
Query:       EEA19562.1  [L=566]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (566 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       570  (0.0317921); expected 358.6 (0.02)
Passed bias filter:                      442  (0.0246528); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.56u 0.25s 00:00:00.81 Elapsed: 00:00:00.41
# Mc/sec: 4161.05
//
Query:       EEA19563.1  [L=412]
Description: MFS monocarboxylate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.8e-19   67.8  61.7      9e-16   57.7  37.8    2.8  2  MFS_1     Major Facilitator Superfamily
     0.0041   16.0  24.0      0.065   12.1   3.3    2.2  2  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.7  37.8     1e-19     9e-16       6     351 ..      46     367 ..      41     369 .. 0.79
   2 !   23.9  15.9   1.9e-09   1.7e-05      53     169 ..     281     400 ..     274     409 .. 0.87

  Alignments for each domain:
  == domain 1  score: 57.7 bits;  conditional E-value: 1e-19
       MFS_1   6 flsalarsilgpal....pl.alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa..sslw.lllvlrvlqG 96 
                 +l ++ ++ + +a+        + +   +s   +g++ ++  +++ ++ + +G+l dr+G+r +l++g ++++ + ++ll a  + +w ++l l +l G
  EEA19563.1  46 CLLMFPSFGFQSAVgsvqDYiSMHQLVEYSIRDVGWISAILVFLTQFLGVQVGPLFDRYGPRILLICGSTASFTS-YILL-AecTKYWhFILCLSILGG 142
                 55555555555555111144444445669***********9999999**************************99.7777.55699**66666666666 PP

       MFS_1  97 lgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeeekgtgpap 195
                 +                f++ +r++  gl +ag+s+G ++ pl+  +l + + W  +   +a+v+l +  l   +++++ + ++  s++          
  EEA19563.1 143 VS-------------SAFHR-RRALPSGLCMAGSSAGGAVIPLILQVLFERGDWKPAIRTVALVALGCYTL--GVIMVRGRLPGHTSKA---------- 215
                 65.............58988.***********************************************666..4443333333333333.......... PP

       MFS_1 196 lvpawkallkdpvlwillialllfffgfsglltllplylqevlgls...glllaglllallalvgailallagrlsdrlgrrrrlllallllllaalgl 291
                 +v+ ++a+++ +   +l +a+++f f+++g  +llp+y +   g+s     ++++++l  ++++g   ++l g+++d +gr + ll  ++++l++ +g+
  EEA19563.1 216 MVD-FRAFRSLRLC-FLTVAVFSFEFIIFGCAALLPTY-VRFAGMSstvQ-FYSLTVLNSMSFMG---RVLPGFVADQFGRFNVLLCLVVVTLVVMAGV 307
                 345.8889998844.59999999999************.999****8643.66666666666666...************8776666666666666666 PP

       MFS_1 292 allavtssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfntagslggal 351
                  l   + + + l++v++++Gf +g   +++ ++a +l+ +e  g+++g + ++ ++g +l
  EEA19563.1 308 WLPWGSRNDATLYAVVAIFGFSSGGWLSLAPVCAGQLCRTEDYGRYYGTIYFVAAFGVLL 367
                 666666666666669999*************************************99887 PP

  == domain 2  score: 23.9 bits;  conditional E-value: 1.9e-09
       MFS_1  53 GrlsdrfGrrrvlllglllfalglllll..fa.sslwlllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllassl 148
                 G+++d fGr  vll+ ++++++ ++  +  ++  +  +l+++ ++ G+ +g+ ++++ + + ++   e+ gr++g ++  +++G++l+ ++g+ l++s 
  EEA19563.1 281 GFVADQFGRFNVLLCLVVVTLVVMAGVWlpWGsRNDATLYAVVAIFGFSSGGWLSLAPVCAGQLCRTEDYGRYYGTIYFVAAFGVLLTVPVGSDLLQST 379
                 99*********999999999999555553555555669************************************************************* PP

       MFS_1 149 gWravfyilaivsllafvlfl 169
                 + +++  +  +v+l++f+  +
  EEA19563.1 380 SPQVLIGFYSAVLLVGFIALA 400
                 *****9999999999999533 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.1   3.3   7.3e-06     0.065      15     113 ..      52     141 ..      39     147 .. 0.81
   2 !    9.7  12.9   3.8e-05      0.34      10     185 ..     233     393 ..     224     408 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 7.3e-06
                 HHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHH CS
    Sugar_tr  15 dtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvG 113
                  +g+ +a+ ++++++++++l +++  +      +g+i +i+++   + ++ +g+l dr+G +  l+++++ ++ + +l a ++   +++ +i++  ++G
  EEA19563.1  52 SFGFQSAVGSVQDYISMHQLVEYSIRD------VGWISAILVFLTQFLGVQVGPLFDRYGPRILLICGSTASFTSYILLAECT---KYWHFILCLSILG 141
                 567788888888888888887777644......59********999999**********************************...6777777755554 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 3.8e-05
                 HHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGG CS
    Sugar_tr  10 llfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivg 108
                  +f + + + g ++ l+ ++++ g+s++++ +          + +++  +++G ++ g+++d fGR ++ll+ +v++++  +   +  g ++   l++ 
  EEA19563.1 233 AVFSFEFIIFGCAALLPTYVRFAGMSSTVQFYS---------LTVLNSMSFMGRVLPGFVADQFGRFNVLLCLVVVTLVVMAGVWLPWGSRNDATLYAV 322
                 567777777777778888888777777776443.........455566689*****************9998666655555555555555677788888 PP

                 HHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHH.HTSS-TTHHHHHHHCCHHHHHHHH CS
    Sugar_tr 109 RvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglgl.nktsnadgwrillglqlvpallll 185
                   + G++ G+   l+P+ ++ ++ ++  g+  +   +  +fG l++  +g  l + ts        + l  + + +ll
  EEA19563.1 323 VAIFGFSSGGWLSLAPVCAGQLCRTEDYGRYYGTIYFVAAFGVLLTVPVGSDLlQSTSP-------QVLIGFYSAVLL 393
                 89*********************9999999999999999*******9999998444444.......222222222333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (412 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       707  (0.0394333); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.31s 00:00:00.89 Elapsed: 00:00:00.51
# Mc/sec: 2448.17
//
Query:       EEA19564.1  [L=711]
Description: hypothetical protein PMAA_003520 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (711 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       493  (0.0274974); expected 358.6 (0.02)
Passed bias filter:                      355  (0.0198003); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.62u 0.31s 00:00:00.93 Elapsed: 00:00:00.48
# Mc/sec: 4431.44
//
Query:       EEA19565.1  [L=573]
Description: ATP sulphurylase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-86  289.5   0.1    1.9e-86  288.9   0.1    1.3  1  ATP-sulfurylase  ATP-sulfurylase
    6.7e-60  201.5   0.1      1e-59  200.9   0.1    1.3  1  APS_kinase       Adenylylsulphate kinase
    5.8e-51  172.3   0.0    9.9e-51  171.6   0.0    1.4  1  PUA_2            PUA-like domain
  ------ inclusion threshold ------
       0.11   13.1   0.0       0.26   11.8   0.0    1.7  1  AAA_18           AAA domain


Domain annotation for each model (and alignments):
>> ATP-sulfurylase  ATP-sulfurylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  288.9   0.1   4.3e-90   1.9e-86       3     211 ..     174     387 ..     172     388 .. 0.98

  Alignments for each domain:
  == domain 1  score: 288.9 bits;  conditional E-value: 4.3e-90
                      CB.-HHHHHHHHHHTT-SSEEEEEESS---HHHHHHHHHHHHH.TSEEEEEEEB-SB-STTSTTHHHHHHHHHHHHHHHS-GGGEEE-BB-SB- CS
  ATP-sulfurylase   3 yrltPaevreefkekgwdkVvAfqtrnplHraHeellkralee.eadglllhplvgptkpgdvpaevrvrayealieeylpkdrvvlallplam 95 
                      +r++Pae+r++f++ gw +VvAfqtrnp+HraH+el+ ra+++ +a+ +l+hp+vg tkpgd+++++rvr y+al+ + +p+ ++vl llplam
       EEA19565.1 174 LRYSPAELRTHFDKLGWTRVVAFQTRNPMHRAHRELTVRAARArQAN-VLIHPVVGLTKPGDIDHFTRVRVYQALLPR-YPNGMAVLGLLPLAM 265
                      799***************************************98888.******************************.*************** PP

                      --SCHHHHHHHHHHHHHTT-SEEEE-TTTT-STC......SS-TTHHHHHHHHCHHHCTSEEEE---EEEETTTTEEEECCCCGCCGGEEE--H CS
  ATP-sulfurylase  96 ryaGprEallhaiirknyGcthfivGrdhagvgd......fYgpydaqellakvagelgiepvkfeeavYckkegevasektchkkeevesisg 183
                      r++GprEa++haiirkn G+thfivGrdhag+g+      fYgpydaq+ ++k+++elgie+v+f+++ Y ++++e++  +    ++++  isg
       EEA19565.1 266 RMGGPREAIWHAIIRKNHGATHFIVGRDHAGPGKnskgveFYGPYDAQHAVEKYRAELGIEVVEFQQVTYLPDTDEYKPVNEVPAGVKTLDISG 359
                      ****************************************************************************9999999*********** PP

                      HHHHCCHHTT----TTTS-HHHHHHHHH CS
  ATP-sulfurylase 184 telrkllregeeipewfsrpevlkvLre 211
                      telr++lr+g +ipewfs+pev+kvLre
       EEA19565.1 360 TELRRRLRSGAHIPEWFSYPEVIKVLRE 387
                      **************************97 PP

>> APS_kinase  Adenylylsulphate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  200.9   0.1   2.3e-63     1e-59       1     157 [.     395     552 ..     395     553 .. 0.98

  Alignments for each domain:
  == domain 1  score: 200.9 bits;  conditional E-value: 2.3e-63
                 S-EEEEEESSTTSSHHHHHHHHHHHHHHTT.--EEEEEHHHHTTTTTTT--SSHHHHHHHHHHHHHHHHHHHHTT-EEEEE----SHHHHHHHHHHHHC CS
  APS_kinase   1 rgvvvwltGlsgsGKstianalekkLvekg.isvylLdGdnvRhgLnkdLgfseedRkenirrvaevaklladaglivlvafisPyreeReaarellee 98 
                 +g++++ltG+ +sGK++ia+al+ +L+++g +sv lL G++vRh+L+++Lgfs+edR++ni+r+a+va +l++ag+ v++a i+Py+++R+aar++++ 
  EEA19565.1 395 QGFTIFLTGYQNSGKDAIARALQVTLNQQGgRSVSLLLGETVRHELSSELGFSREDRDKNIQRIAFVAAELTKAGAAVIAAPIAPYEASRKAARDTISA 493
                 699**************************989******************************************************************9 PP

                 HTEEEEEEEE--HHHHHHHTTTSHHHHHHTTSSSSHTTTSS-----SS-SEEEETTTS- CS
  APS_kinase  99 alkfievfvdtplevceerDpkglYkkareGeikeftGidspYeaPenpelvvdtdkes 157
                   +fi v+v tple+ce++D++g+Y+kar+Geik+ftG+d+pYeaP +++lvvd++k++
  EEA19565.1 494 VGTFILVHVATPLEYCEKTDKRGIYEKARRGEIKGFTGVDDPYEAPVKADLVVDVEKQT 552
                 9*****************************************************99876 PP

>> PUA_2  PUA-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  171.6   0.0   2.2e-54   9.9e-51       2     158 ..       4     164 ..       3     165 .. 0.97

  Alignments for each domain:
  == domain 1  score: 171.6 bits;  conditional E-value: 2.2e-54
                 S-TTSS----B--CH.HHHHHHHHHHTS-EEE--HHHHHHHHHHHTTTTTT-SCC--HHHHHHHHHHSEETTS-E-SS---EEEECCHCHH..HTT-SE CS
       PUA_2   2 kphggkLvelvvede.ekeellkeakelpsielskrelqdlellaeGgfsPLegFmreedyesvleemrLadgllwsiPivLdvseedakk..lkegdr 97 
                 +phgg L++lv++d+ +++el++ea++lp+i l++r+l+dlel+++GgfsPLegFm+e+dy+ v+ e rLadg l+s+Pi+Ld+s e++k+  lk+g+r
  EEA19565.1   4 PPHGGILKDLVARDApRHDELEAEAATLPAILLTERQLCDLELIMNGGFSPLEGFMNEKDYDGVVAESRLADGNLFSMPITLDASGETIKDlgLKAGSR 102
                 6**************9999***********************************************************************9999***** PP

                 EEEEETT.TEEEEEEEEEEEEE-HHHHHHHHHHS---TTSHHHHHHC.TS-SEEEEEEEEE-S CS
       PUA_2  98 vaLkdke.gellAileveeiyeldkeeeaekvfgttdeaHPgvkkvl.eqgevlvgGkvevle 158
                 v+L+d + ++ lAil++++iy++dk++ea+ vfg+++e HP++ ++  + +e+++gGkve+++
  EEA19565.1 103 VTLRDFRdDRNLAILTIDDIYRPDKTKEAQLVFGGDEE-HPAIVYLNtKVQEFYIGGKVEAVN 164
                 *****996777************************997.*******9999**********998 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   5.8e-05      0.26       1      42 [.     399     441 ..     399     489 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 5.8e-05
      AAA_18   1 IlltGtpGvGKttlakeLskrlgf.gvnlrdvakenglllevd 42 
                 I+ltG++ +GK  +a++L+  l+  g ++ +++  +  + e  
  EEA19565.1 399 IFLTGYQNSGKDAIARALQVTLNQqGGRSVSLLLGETVRHELS 441
                 99****************8887546555555554444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (573 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       347  (0.0193541); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 3881.63
//
Query:       EEA19566.1  [L=747]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.3e-15   56.5   0.0    7.8e-15   55.3   0.0    1.7  1  Methyltransf_11  Methyltransferase domain
    8.2e-12   45.7   0.0    2.5e-11   44.1   0.0    1.9  2  Methyltransf_25  Methyltransferase domain
    1.6e-07   31.2   0.0    3.2e-07   30.3   0.0    1.5  1  Methyltransf_31  Methyltransferase domain
    6.7e-07   29.3   0.0    1.1e-06   28.5   0.0    1.4  1  Methyltransf_23  Methyltransferase domain
    8.9e-07   29.6   0.0    3.2e-06   27.8   0.0    2.0  2  Methyltransf_12  Methyltransferase domain
    3.8e-05   23.1   0.0    6.9e-05   22.3   0.0    1.3  1  Ubie_methyltran  ubiE/COQ5 methyltransferase family


Domain annotation for each model (and alignments):
>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.3   0.0   2.6e-18   7.8e-15       1      95 [.      49     141 ..      49     142 .. 0.89

  Alignments for each domain:
  == domain 1  score: 55.3 bits;  conditional E-value: 2.6e-18
                      EEET-TTSHHHHHHH..HTTSEEEEEES-HHHHHHHHHHCCHHT-EEEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHHHEEEEE CS
  Methyltransf_11   1 LdvGcGtGrlaeala..krgarvvgvDlskemlklakekaseeglkvefvvadaeklpfednsfDlvvssevlhhvedpekalkeiaRvLkpgG 92 
                      +d+++GtG+++eala    g+++++v++ +em+k  + k+ +    v++v++ a++l++e++s+D v++++++h+++   + l+ei+R+Lkp+G
       EEA19566.1  49 VDLAAGTGLFTEALAvrPEGYEIIAVEPHDEMRKELEGKGLN---GVSVVKGYAQELQIESGSVDGVFATQAFHWFA-TLDSLQEIRRILKPDG 138
                      599************76666*************666444443...4899***************************6.7789************ PP

                      EEE CS
  Methyltransf_11  93 llv 95 
                      +++
       EEA19566.1 139 YFA 141
                      *97 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.1   0.0   8.4e-15   2.5e-11       1      97 []      48     138 ..      48     138 .. 0.92
   2 ?   -3.0   0.0       4.3   1.3e+04      69      94 ..     511     536 ..     486     537 .. 0.74

  Alignments for each domain:
  == domain 1  score: 44.1 bits;  conditional E-value: 8.4e-15
                      EEEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHHTTT.TEEEEESBCCGBSSSTTTEEEEEEESTGGGSSHHHHHHHHHHHHHHE CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlgkakvtgvDiseemleaareraeeegl.nvefvqgdaedlpfedgsfDlvvssgalhhlsdedlekalkeiarvL 93 
                      ++dl++GtG +t+ala r + +++++v++ +em ++ + +     l  v++v+g a++l+ e+gs+D v++++a+h++    + + l+ei+r+L
       EEA19566.1  48 IVDLAAGTGLFTEALAVRPEGYEIIAVEPHDEMRKELEGKG----LnGVSVVKGYAQELQIESGSVDGVFATQAFHWFA---TLDSLQEIRRIL 134
                      89**************99735************99988888....548***********************988***98...4569******** PP

                      EEEE CS
  Methyltransf_25  94 kpgG 97 
                      kp+G
       EEA19566.1 135 KPDG 138
                      ***9 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 4.3
                      EEESTGGGSSHHHHHHHHHHHHHHEE CS
  Methyltransf_25  69 vssgalhhlsdedlekalkeiarvLk 94 
                        + ++h ++  dl++al+ + +vLk
       EEA19566.1 511 STALGVHSVQSGDLATALSVFTSVLK 536
                      33344777888888888888888887 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.3   0.0   1.1e-10   3.2e-07       3     113 ..      44     146 ..      42     189 .. 0.86

  Alignments for each domain:
  == domain 1  score: 30.3 bits;  conditional E-value: 1.1e-10
  Methyltransf_31   3 kglrvlDlGCGtGeltfelaeelgp.kaevvGiDiseeaielArenaqklgldnveFeqgdieeleklledekfDlilsnevlnaladpdkile 95 
                      ++l+++Dl++GtG +t +la  ++p + e++ ++   e+    r++++ +gl+ v++ +g ++el+  +e  ++D +++ ++++ +a   + l+
       EEA19566.1  44 QDLKIVDLAAGTGLFTEALA--VRPeGYEIIAVEPHDEM----RKELEGKGLNGVSVVKGYAQELQ--IESGSVDGVFATQAFHWFA-TLDSLQ 128
                      7899****************..6663778*******986....888999*****************..99*************5555.55679* PP

  Methyltransf_31  96 eiervlkpggilliedpr 113
                      ei r lkp+g++++  + 
       EEA19566.1 129 EIRRILKPDGYFAMIWHV 146
                      ************997666 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.5   0.0   3.8e-10   1.1e-06       1     120 [.      19     145 ..      19     172 .. 0.80

  Alignments for each domain:
  == domain 1  score: 28.5 bits;  conditional E-value: 3.8e-10
  Methyltransf_23   1 ydaqreeelsdklerllpk....lraggrvLdiGcGtGillevl..rengfsvtgvDlspeaveiae..kakkaqkdqfdeqeaaepqgkfdlI 86 
                      yd++r+ +  ++++ +l +    +r++ +++d+++GtG ++e l  r++g+++++v++ +e+ +++e  +      ++ ++qe + ++g+ d +
       EEA19566.1  19 YDKHRPTYTTHETDLILNRthcaNRQDLKIVDLAAGTGLFTEALavRPEGYEIIAVEPHDEMRKELEgkGLNGVSVVKGYAQELQIESGSVDGV 112
                      6677776677777776655566699999************99999999******************99955555555555688888******** PP

  Methyltransf_23  87 vlrevlehvpdppellrqiatllkpgGylllsep 120
                       +++ ++++  + + l+ i+++lkp+Gy+    +
       EEA19566.1 113 FATQAFHWFATLDS-LQEIRRILKPDGYFAMIWH 145
                      ***********888.*************866555 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0   1.1e-09   3.2e-06       1      99 []      49     140 ..      49     140 .. 0.92
   2 ?   -2.7   0.0       3.4     1e+04      64      79 ..     515     534 ..     470     541 .. 0.56

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 1.1e-09
  Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvelealdlldldggssfDlvvasnvlhhlkdirevldnirklLk 94 
                      +++ +GtG +++al+ + ++ e+++v+++ ++     ++l  ++ n +++v+  a++l  ++g  s+D v+a +++h++  + ++l++ir+ Lk
       EEA19566.1  49 VDLAAGTGLFTEALAVRPEGYEIIAVEPHDEMR----KELEGKGLNGVSVVKGYAQELQIESG--SVDGVFATQAFHWF-ATLDSLQEIRRILK 135
                      5899*****************************....999999999********999877665..*************8.55678********* PP

  Methyltransf_12  95 pgGrl 99 
                      p+G++
       EEA19566.1 136 PDGYF 140
                      ***85 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 3.4
  Methyltransf_12  64 g....ssfDlvvasnvlhhl 79 
                      g    +s Dl +a++v+  +
       EEA19566.1 515 GvhsvQSGDLATALSVFTSV 534
                      13445677777777777655 PP

>> Ubie_methyltran  ubiE/COQ5 methyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.3   0.0   2.3e-08   6.9e-05      43     152 ..      40     143 ..      16     157 .. 0.83

  Alignments for each domain:
  == domain 1  score: 22.3 bits;  conditional E-value: 2.3e-08
                      --S--TTEEEEES-TT-HHHHHHHHHHHHHH.EEEEEES-HHHHHHHHHHHHHHTSSTEEEEE--TTT-TTS-T-EEEEEEES-GGG-S-HHHH CS
  Ubie_methyltran  43 vavkrgakvlDvagGtgDlafklsdsvgekg.kvvvlDinenmLkvgekklkeegkinieflqanaeeLpfeddsfDvvtvsfGlrnvtDklka 135
                       a+++  k++D+a+Gtg ++ +l+  v+ +g +++ ++  ++m    +k l+ +g   +  +++ a+eL+ e +s D v  +  +  ++  l +
       EEA19566.1  40 CANRQDLKIVDLAAGTGLFTEALA--VRPEGyEIIAVEPHDEM----RKELEGKGLNGVSVVKGYAQELQIESGSVDGVFATQAFHWFAT-LDS 126
                      3567778***********999996..66666589999988888....5668889999********************9988888888774.668 PP

                      HHHHHHHEEEEEEEEEE CS
  Ubie_methyltran 136 LkeayrvlkpGGrlvvl 152
                      L+e++r+lkp G + ++
       EEA19566.1 127 LQEIRRILKPDGYFAMI 143
                      ************99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (747 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       483  (0.0269396); expected 358.6 (0.02)
Passed bias filter:                      436  (0.0243181); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.70u 0.28s 00:00:00.98 Elapsed: 00:00:00.49
# Mc/sec: 4627.81
//
Query:       EEA19567.1  [L=287]
Description: hypothetical protein PMAA_003550 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.7e-08   33.6   0.0    7.3e-08   32.7   0.0    1.5  1  Acetyltransf_1   Acetyltransferase (GNAT) family
    4.9e-06   26.5   0.0    9.3e-06   25.6   0.0    1.4  1  Acetyltransf_10  Acetyltransferase (GNAT) domain
    8.8e-05   22.9   0.0    0.00035   20.9   0.0    1.9  2  Acetyltransf_7   Acetyltransferase (GNAT) domain
  ------ inclusion threshold ------
      0.011   16.4   0.6       0.26   11.9   0.0    2.4  2  Acetyltransf_3   Acetyltransferase (GNAT) domain
      0.048   13.6   0.0       0.11   12.5   0.0    1.5  1  FR47             FR47-like protein


Domain annotation for each model (and alignments):
>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.7   0.0     2e-11   7.3e-08      41     117 .]      96     236 ..      50     236 .. 0.71

  Alignments for each domain:
  == domain 1  score: 32.7 bits;  conditional E-value: 2e-11
                     T.....TEEEEEE...........................................................EEEEEET.........TSTTEEE CS
  Acetyltransf_1  41 d.....geliGfi...........................................................sllkipd.........ekggvay 62 
                     +     ++++Gf+                                                                           + +++++
      EEA19567.1  96 EgigggEKVVGFAiwnrhgdsetaqkwrvegskvstriksmmsyitmtltypfdtsinhthmtnfqrrvrtaP-----SplpsgqklkLPRERWE 185
                     1555556788888888888888888888888888888888777777777777776666666666666443330.....244555555556899** PP

                     EEEEEESGGGTTSSHHHHHHHHHHHHHHHTTESEEEEEEETTEHHHHHHHHHTTE CS
  Acetyltransf_1  63 ieslaVspeyrgkGlGsaLlealeerareegikkivlaveedndaairlYeklGF 117
                     +e l+++p+y+++G+G + l+  ++ areeg++  v+      d   ++Yek GF
      EEA19567.1 186 LEALYIAPDYQRRGYGMEALKWGLDVAREEGVDVWVW-S---SDSGKKVYEKGGF 236
                     ********************************99555.3...4556999999887 PP

>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.0   2.6e-09   9.3e-06      48     111 ..     179     241 ..     176     246 .. 0.90

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 2.6e-09
  Acetyltransf_10  48 l.rdgshisllfVdpeyrgqGigkaLleaveeeaekdgikleltvnaspyavpfYeklGFkavge 111
                      l r++++++ l+++p+y+++G+g + l+  ++ a+++g   ++ v +s+  +++Yek GF+avg+
       EEA19567.1 179 LpRERWELEALYIAPDYQRRGYGMEALKWGLDVAREEGV--DVWVWSSDSGKKVYEKGGFEAVGR 241
                      5578899**************************976644..7********************997 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0      0.82     3e+03       5      19 ..      78     109 ..      74     122 .. 0.62
   2 !   20.9   0.0   9.9e-08   0.00035      26      75 ..     185     237 ..     170     238 .. 0.72

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.82
                     EEEEEET.................TEEEEEEE CS
  Acetyltransf_7   5 vfVaedd.................gkivGfia 19 
                     ++V++                   +k+vGf++
      EEA19567.1  78 CWVVYVHdhnqsvddandegigggEKVVGFAI 109
                     56655444555555556556666666667665 PP

  == domain 2  score: 20.9 bits;  conditional E-value: 9.9e-08
                     CTEEEEE-GGGTTSSHHHHHHHH.....TTSEEEEEEEEE..THHHHHHHHHHTTEE CS
  Acetyltransf_7  26 eitrlaVdpeyrgkGiGraLlea.....aekgiileqlel..naekaikfYeklGFe 75 
                     e++ l+++p+y+++G+G + l+      +e+g+    +++  ++    k Yek GFe
      EEA19567.1 185 ELEALYIAPDYQRRGYGMEALKWgldvaREEGVD---VWVwsSD-SGKKVYEKGGFE 237
                     4555*****************9755543226643...3444233.6788*******8 PP

>> Acetyltransf_3  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.2     0.046   1.6e+02       4      57 ..       3      57 ..       1     124 [. 0.67
   2 ?   11.9   0.0   7.4e-05      0.26      78     116 ..     181     219 ..     151     242 .. 0.81

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.046
  Acetyltransf_3  4 LrplteeDlealfel...rsdpe.vmrylpepltleeaeewlerawaeeseeegygwa 57
                    Lrp+t++D  al+ +   ++  + + ry ++  +++e ++ ++   +  + +++ +w 
      EEA19567.1  3 LRPYTPHDSLALATItaaCNLTDpLARYCRH-INRDEYQHQQTADHN--NGDDDIQWK 57
                    9******966665542224444445667665.445555544442122..223334444 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 7.4e-05
  Acetyltransf_3  78 deeaelg.ymlapsfwgkGyateavralleyafeelgler 116
                     +e++el+ +++ap+++++Gy+ ea++  l++a +e+g++ 
      EEA19567.1 181 RERWELEaLYIAPDYQRRGYGMEALKWGLDVA-REEGVDV 219
                     344899867899**************999999.4554654 PP

>> FR47  FR47-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   2.9e-05      0.11      23      79 ..     185     238 ..     179     242 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 2.9e-05
                 SEEEEEE-GGG-SSSHHHHHHHHHHHHHHHS-S-EEEEEETT-HHHHHHHHHHT-EE CS
        FR47  23 elgalqvlpehrrrGlgsrlvkalakeiaergktvllvvvasNtpsirlyeklGfek 79 
                 el al++ p+ +rrG+g     al  ++  + ++ + v+v s +   ++yek Gfe+
  EEA19567.1 185 ELEALYIAPDYQRRGYGME---ALKWGLDVAREEGVDVWVWSSDSGKKVYEKGGFEA 238
                 799**************85...66666666444444455556667899999999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (287 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       365  (0.0203581); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 1909.08
//
Query:       EEA19568.1  [L=566]
Description: MFS monosaccharide transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   8.9e-130  433.5  29.9     1e-129  433.3  29.9    1.0  1  Sugar_tr         Sugar (and other) transporter
    2.7e-22   79.2  43.2    1.2e-14   54.0  18.3    2.4  2  MFS_1            Major Facilitator Superfamily
    0.00032   19.4  26.4     0.0013   17.4   0.2    3.5  4  MFS_2            MFS/sugar transport protein
      0.003   17.7   3.7      0.019   15.1   0.2    2.8  2  Pox_A14          Poxvirus virion envelope protein A14
  ------ inclusion threshold ------
       0.64    9.2  11.5      0.068   12.4   3.5    2.5  2  O_anti_polymase  Putative O-antigen polymerase
        2.2    8.5   8.2        5.2    7.3   1.9    2.9  2  DUF4293          Domain of unknown function (DUF4293)


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  433.3  29.9  3.5e-133    1e-129       3     452 .]      68     523 ..      66     523 .. 0.96

  Alignments for each domain:
  == domain 1  score: 433.3 bits;  conditional E-value: 3.5e-133
                 HHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS CS
    Sugar_tr   3 lvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgkns 101
                 l++++gg++fgYdtg i++fl + +f++ fg  + ++ +e s+v+sgli++++++G +iG+l++ +++dr+GRk+s+ + ++++++g  +q+ +  + +
  EEA19568.1  68 LFVSMGGFIFGYDTGQISGFLQMEDFLYSFGEWNGEK-YEFSDVRSGLITGLLSIGTLIGALVGAPIADRIGRKWSISFWCIILCVGVTVQISSS-QGK 164
                 6789**************************9777776.4448*****************************************************.66* PP

                 -TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHH CS
    Sugar_tr 102 vevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPrylve 200
                 +++++vgR+++G+gvG+ s +vPmy++E  p ++Rgal+slyql+it+Gi+va+++++g++ ++ +  wril+g+++++a++l ++++f+PESPr+ + 
  EEA19568.1 165 WYQVAVGRLIAGLGVGALSLIVPMYQGESGPRHIRGALISLYQLFITLGIFVAYCIDFGTEAMTTSASWRILMGITYLWAIILGVGIIFFPESPRFDYR 263
                 ************************************************************6666669******************************** PP

                 TT-HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH.........HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THHHHHHHH CS
    Sugar_tr 201 kgkeeeakevlaklrgeedadrelaeekdsleaeqeee....kaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsksllvtii 295
                 +gk ++a + lak+ g ++++r+la+e+++++++ eee    +++w ++l+   +++r+++g++lq++qqltG n+++yy++tif+ +g+s+s+++ +i
  EEA19568.1 264 HGKVDRAVANLAKIYGIPQNHRALAQEFEEIKEKYEEEkshgNITWWMMLGAPRMKYRIMVGMLLQALQQLTGANYFFYYGTTIFQGAGISNSFVTQMI 362
                 *****************9999999999999999988888899**********99********************************************* PP

                 HHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH...HHHHTTSS.......CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHH CS
    Sugar_tr 296 vgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilg.ivalllvaks....kaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskala 389
                 +g vnf +tf +++ + +fGRR+ l+ Ga+ m++cf+i++ i  + l  ++     aa+ +++ f ++fi  +a +w+p++w +++El+p+++R+ a+a
  EEA19568.1 363 LGGVNFGTTFLGLYNIQHFGRRKSLIAGAIWMFVCFLIFAsIGHFSLDRQTpantPAAGKAMVCFACFFILGYASTWAPMVWAICAELYPSEFRARAMA 461
                 ****************************************7666666665589999******************************************* PP

                 HHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 390 iavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 +++a+nwl+nfl ++++p+it+ai  + +++vfag++ +++++v+f v+e k rtleei++++
  EEA19568.1 462 MSTASNWLWNFLLAFFTPFITSAID-FRFGYVFAGCMFATAFVVYFAVIEGKDRTLEEIDTMY 523
                 *************************.**********************************996 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.0  18.3     4e-18   1.2e-14      15     256 ..      93     366 ..      64     377 .. 0.70
   2 !   28.6  19.8   2.2e-10   6.5e-07      50     179 ..     371     513 ..     357     542 .. 0.75

  Alignments for each domain:
  == domain 1  score: 54.0 bits;  conditional E-value: 4e-18
       MFS_1  15 lgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfa.sslw.lllvlrvlqGlgagalfpagaali 110
                 ++ ++ ++ +e + +s    gl+++l ++g+++++l++++++dr+Gr++ + +  +++++g ++ ++ + ++ w  ++v+r+++Glg gal  ++  + 
  EEA19568.1  93 FLYSFGEWNGEKYEFSDVRSGLITGLLSIGTLIGALVGAPIADRIGRKWSISFWCIILCVGvTVQIS-SsQGKWyQVAVGRLIAGLGVGALSLIVPMYQ 190
                 2223333445566688888******************************777666777777233333.24666669*********************** PP

       MFS_1 111 adwfpkeergraigllsagfslGailgpllgg...llasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.................. 188
                  +  p+  rg  i+l+++++ lG+ +++ +     ++++s++Wr ++ i  + +++++v +++++pe+p+   r  ++++                   
  EEA19568.1 191 GESGPRHIRGALISLYQLFITLGIFVAYCIDFgteAMTTSASWRILMGITYLWAIILGV-GIIFFPESPRFDYRHGKVDRAvanlakiygipqnhrala 288
                 ***************************99965567999********9999999999999.569**9999999999999998999999999888777665 PP

       MFS_1 189 ..........kgtgpaplvp.......awkallkdpvlw.....illialllfffgfsglltllplylqevlgls.glllaglllallalv 256
                           +        +        w ++l  p +       +l+ +l   +g ++++++ +++  +  g+s +   ++   ++l+ v
  EEA19568.1 289 qefeeikekyE--------EekshgniTWWMMLGAPRMKyrimvGMLLQALQQLTGANYFFYYGTTI-FQGAGISnS--FVT--QMILGGV 366
                 55554444332........033334443555555555523323444444444455666677777775.788888841..222..3333333 PP

  == domain 2  score: 28.6 bits;  conditional E-value: 2.2e-10
       MFS_1  50 lplGrl.sdrfGrrrvlllglllfalglllll....fa......sslw.l.....llvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfs 131
                  +lG   ++ fGrr+ l++g++++++++l+++    f+      ++ + +      +++ ++ G + ++ +p++ a+ a+++p e r+ra+++ +a++ 
  EEA19568.1 371 TFLGLYnIQHFGRRKSLIAGAIWMFVCFLIFAsighFSldrqtpANTPaAgkamvCFACFFILGYA-STWAPMVWAICAELYPSEFRARAMAMSTASNW 468
                 4555553788*****************666666444424555553433225553355555566665.67778888************************ PP

       MFS_1 132 lGailgpllggllasslgWravfyilaivsllafvlfllllpeepper 179
                 l   l + + ++++s++ +r  +++++ +++ afv   +++ + + + 
  EEA19568.1 469 LWNFLLAFFTPFITSAIDFRFGYVFAGCMFATAFV---VYFAVIEGKD 513
                 *********************************99...5554333333 PP

>> MFS_2  MFS/sugar transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.2   4.3e-07    0.0013     263     336 ..     114     187 ..     100     192 .. 0.86
   2 ?   -1.0   1.5      0.16   4.9e+02     371     420 ..     202     254 ..     198     256 .. 0.81
   3 !   15.6   6.6   1.5e-06    0.0044     199     340 ..     294     448 ..     286     466 .. 0.72
   4 ?   -1.8   1.4      0.29   8.8e+02     263     306 ..     462     506 ..     438     524 .. 0.59

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 4.3e-07
       MFS_2 263 vfllvvtisallgiplwqplakrlgkkntyllgalltivllvlvlllqpsnlllflvllviagfgvgvaallpw 336
                 ++++++ i++l+g+++ +p+a r+g+k ++ +  +++ v+ ++ +  ++++++ + v  +iag+gvg++ l+++
  EEA19568.1 114 LITGLLSIGTLIGALVGAPIADRIGRKWSISFWCIILCVGVTVQISSSQGKWYQVAVGRLIAGLGVGALSLIVP 187
                 5788999********************776666666677777777777*******************9988765 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.16
       MFS_2 371 giglgvsgllLsaf.gy..rakasvqspqvvlalrllyavlpavlllvallll 420
                  i+l  +++ L++f  y  + +  + + ++ +++ + +++l a++l v+++++
  EEA19568.1 202 LISLYQLFITLGIFvAYciDFGTEAMTTSASWRILMGITYLWAIILGVGIIFF 254
                 56777777777777677778889999999999999999999999999999875 PP

  == domain 3  score: 15.6 bits;  conditional E-value: 1.5e-06
       MFS_2 199 m.rkkekteqkeklslleqlkevfrnraflillllfllaalalgvlnglllYyltyvlg.ngsaasvfllvvtisal..lgiplwqplakrlgkkntyl 293
                   +k e++++ + ++++++l++   +    +++++ ll+al ++ +++ + Yy t +   +g   s+++  ++++++   +++l  +  +++g++++ +
  EEA19568.1 294 IkEKYEEEKSHGNITWWMMLGAPRMK---YRIMVGMLLQALQQLTGANYFFYYGTTIFQgAGISNSFVTQ-MILGGVnfGTTFLGLYNIQHFGRRKSLI 388
                 34567788888889999998876555...78999*********************999845544444444.455555557777778889********** PP

       MFS_2 294 lgalltivllvlvlll..............qpsnlllflvllviagfgvgvaallpwsmla 340
                 +ga+ ++v ++++  +               +++ ++ +++++i g +  + a ++w++ a
  EEA19568.1 389 AGAIWMFVCFLIFASIghfsldrqtpantpAAGKAMVCFACFFILGYA-STWAPMVWAICA 448
                 ********999999999*******665554444444444444444433.344445555554 PP

  == domain 4  score: -1.8 bits;  conditional E-value: 0.29
       MFS_2 263 vfllvvtisallgiplwqplakrlgkk.ntyllgalltivllvlv 306
                 ++++   + ++l +++ + +++ ++ +  ++++g +++ ++ v +
  EEA19568.1 462 MSTASNWLWNFLLAFFTPFITSAIDFRfGYVFAGCMFATAFVVYF 506
                 444444555556666666666666644233333333333333333 PP

>> Pox_A14  Poxvirus virion envelope protein A14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.2   6.2e-06     0.019      22      66 ..     210     255 ..     197     271 .. 0.85
   2 ?    2.3   0.3     0.065   1.9e+02      16      60 ..     388     439 ..     379     450 .. 0.57

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 6.2e-06
     Pox_A14  22 Lilacifaf.vdfskststtdkawralsivsFilgivillglllfs 66 
                 ++l + +a+ +df  +  tt   wr l +++++ +i++ +g++ f 
  EEA19568.1 210 ITLGIFVAYcIDFGTEAMTTSASWRILMGITYLWAIILGVGIIFFP 255
                 34566668768********99**********************985 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.065
     Pox_A14  16 iaG.iiLLilacifafv.dfs..kstst.tdkawral.sivs.Filgivill 60 
                 iaG i + +  +ifa +  fs  ++t++ t  a +a+ +  + Filg +++ 
  EEA19568.1 388 IAGaIWMFVCFLIFASIgHFSldRQTPAnTPAAGKAMvCFACfFILGYASTW 439
                 4441455666677876633551155554455555654255553577777665 PP

>> O_anti_polymase  Putative O-antigen polymerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   3.5   2.3e-05     0.068     234     297 ..     179     241 ..     167     252 .. 0.84
   2 ?    1.1   0.8     0.065   1.9e+02     109     163 ..     388     446 ..     362     509 .. 0.50

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2.3e-05
  O_anti_polymase 234 hGklllsaitsl.sssgprvligklilgrevsiTsTlfGpvllDFGllgvliqmlilgllLgily 297
                       G+l+l  ++++  +sgpr++ g li  ++  iT  +f +  +DFG+ ++        +l+gi y
       EEA19568.1 179 VGALSLI-VPMYqGESGPRHIRGALISLYQLFITLGIFVAYCIDFGTEAM-TTSASWRILMGITY 241
                      5666655.6665689***********************************.57777788888877 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.065
  O_anti_polymase 109 lntkltalsy.lflpsiailva...kvarlrnlilfiiglvllallgYrttvlaillsi 163
                      ++ ++++++  l+  si+         a+  +    +++++++++lgY  t   ++ +i
       EEA19568.1 388 IAGAIWMFVCfLIFASIGHFSLdrqTPANTPAAGKAMVCFACFFILGYASTWAPMVWAI 446
                      33334444333444444433332222222333333444444444444443333332222 PP

>> DUF4293  Domain of unknown function (DUF4293)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.5     0.022        65       9     121 ..     118     236 ..     118     253 .. 0.62
   2 ?    7.3   1.9    0.0018       5.2      17     129 ..     324     430 ..     320     440 .. 0.64

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.022
     DUF4293   9 Lllaailmaaflflplasivtedellsfyalgvs.taeaetsvnvsvwvlvilllliailaliaIfl....yk..nRklQlrlclinllllvllyvlla 100
                 Ll +  l++a++  p+a  + ++ ++sf+ +++    + ++s ++  w+ v++ +lia l + a+ l    y+    +  +r  li+l  l +++++++
  EEA19568.1 118 LLSIGTLIGALVGAPIADRIGRKWSISFWCIILCvGVTVQISSSQGKWYQVAVGRLIAGLGVGALSLivpmYQgeSGPRHIRGALISLYQLFITLGIFV 216
                 566677889999999999999998888888877656677888899999999999999997665544311113311334666666666666666666666 PP

     DUF4293 101 llllvnkanaaaeslgesslk 121
                 ++ + + ++a ++s  ++++ 
  EEA19568.1 217 AYCIDFGTEAMTTSA-SWRIL 236
                 644444444444433.33333 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0018
     DUF4293  17 aaflflplasivtedellsfyalgvstaeaetsvnvsvwvlvilllliailaliaIflyknRklQlrlclinllllvllyvllallllvnkanaaaesl 115
                 + +l l+  ++ t ++ +  y +++ + ++ ++ +v+ ++l  ++  +++l l++I  + +Rk  +   ++  + +++++ +    + +  ++ a+++ 
  EEA19568.1 324 VGML-LQALQQLTGANYFFYYGTTIFQGAGISNSFVTQMILGGVNFGTTFLGLYNIQHFGRRKSLIAGAIWMFVCFLIFASIGH--FSLDRQTPANTPA 419
                 4444.344444555555666677777788888999999************************9766555444443333333333..3556666666666 PP

     DUF4293 116 gesslkiglilpli 129
                      k+ +++ ++
  EEA19568.1 420 ---AGKAMVCFACF 430
                 ...33444444333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (566 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       784  (0.043728); expected 358.6 (0.02)
Passed bias filter:                      434  (0.0242066); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.67u 0.31s 00:00:00.98 Elapsed: 00:00:00.47
# Mc/sec: 3589.45
//
Query:       EEA19569.1  [L=724]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.32   11.4   5.2       0.58   10.5   5.2    1.5  1  EGF       EGF-like domain


Domain annotation for each model (and alignments):
>> EGF  EGF-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   5.2   3.3e-05      0.58       1      30 [.     451     480 ..     451     482 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 3.3e-05
                 GCS.TTSTTT-EEEEET.TTEEEEEECTTEES CS
         EGF   1 Csp.npCsngGtCvdtg.rggytCiCpeGytG 30 
                 C +  pC+ngG  v+++ + + +C C +G++G
  EEA19569.1 451 CEQkLPCMNGG--VSVQsGSTCSCVCVNGFSG 480
                 78889******..666666************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (724 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       812  (0.0452898); expected 358.6 (0.02)
Passed bias filter:                      350  (0.0195214); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.66u 0.31s 00:00:00.97 Elapsed: 00:00:00.47
# Mc/sec: 4641.42
//
Query:       EEA19570.1  [L=279]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.069   13.8   5.0       0.14   12.8   1.7    2.6  2  Adaptin_binding  Alpha and gamma adaptin binding protein p34
        0.2   11.3   3.1       0.44   10.3   3.1    1.6  1  DUF4637          Domain of unknown function (DUF4637)


Domain annotation for each model (and alignments):
>> Adaptin_binding  Alpha and gamma adaptin binding protein p34
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.1       0.1   9.4e+02      80     102 ..      23      45 ..       6      62 .. 0.48
   2 ?   12.8   1.7   1.6e-05      0.14      21     107 ..     125     269 ..     122     272 .. 0.80

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.1
  Adaptin_binding  80 gdeaarledlesllsklqqakdn 102
                      + ++a   +++  +++l ++ ++
       EEA19570.1  23 KRNNAATTSFDEKVQQLDNLLER 45 
                      22233333444444444444333 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 1.6e-05
  Adaptin_binding  21 elkkqtaslsnrnasleteadeaqlekeeeeqdpsqpastepdksaaesesadaef...................................... 76 
                      e k++ +s ++++++l+ + ++ ++ + e+  d+ qp+ t++++++ae+ s+ +                                        
       EEA19570.1 125 EYKSVINSKNDEQEELNDAGQDVEKAATETVADDTQPDHTDETNQQAEKSSGITTPptqpqdaaknnnedkgtgsttktksetvtkkkkkifrs 218
                      5667777777788888888899999999999999999998888877777776666588888888888888888889999999999999999999 PP

  Adaptin_binding  77 ....................lfggdeaarledlesllsklqqakdnvrnlp 107
                                          +f +  ++ +  l s++s+++ + d+v +l 
       EEA19570.1 219 ddpiswygilvpsslksaqkSFTEAIDDGIPHLVSVISEMRRVEDMVYELR 269
                      999999999999888887777777777777799999999999999998775 PP

>> DUF4637  Domain of unknown function (DUF4637)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   3.1   4.9e-05      0.44      13      97 ..     150     235 ..     118     261 .. 0.72

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 4.9e-05
     DUF4637  13 eareveeeeaeeeseeedeeedraeeesa.aegeeesreaeeaegrekgsvsysPlrqessaqevallrrads..gfwgwlsPlalls 97 
                  a+e+ +++++ +  + de++++ae+ s  +   +++++a ++++++kg+ s +  + e+ +++   + r+d   +++g l P +l s
  EEA19570.1 150 AATETVADDTQPD--HTDETNQQAEKSSGiTTPPTQPQDAAKNNNEDKGTGSTTKTKSETVTKKKKKIFRSDDpiSWYGILVPSSLKS 235
                 2333333333222..22333334444443144449999**************************999999997446789999988865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (279 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1489  (0.0830498); expected 358.6 (0.02)
Passed bias filter:                      533  (0.0297284); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 1777.95
//
Query:       EEA19571.1  [L=113]
Description: iron-sulfur cluster biosynthesis protein Isd11, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.6e-18   65.4   5.0    3.6e-18   65.4   5.0    1.7  2  Complex1_LYR    Complex 1 protein (LYR family)
      8e-06   26.5   2.8    9.6e-06   26.3   2.8    1.1  1  Complex1_LYR_2  Complex1_LYR-like
      0.005   16.4   0.1     0.0052   16.3   0.1    1.1  1  NA37            37-kD nucleoid-associated bacterial protein


Domain annotation for each model (and alignments):
>> Complex1_LYR  Complex 1 protein (LYR family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.4   5.0     6e-22   3.6e-18       2      59 .]      14      71 ..      13      71 .. 0.98
   2 ?   -1.3   0.0      0.39   2.4e+03      42      55 ..      80      93 ..      73      96 .. 0.80

  Alignments for each domain:
  == domain 1  score: 65.4 bits;  conditional E-value: 6e-22
  Complex1_LYR  2 qvLsLYRalLRearkfpdyntreyfrrriRdeFrknkhvtDpekieellkkgreeLee 59
                  qv sL+Ral+R++++f++yn+rey+rrr+Rd Fr+++++  ++ki+e++++g ++L +
    EEA19571.1 14 QVRSLFRALMRQSSQFSNYNFREYARRRTRDAFREHQKEGEERKIQEFIQDGLKNLRM 71
                  89*****************************************************976 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.39
  Complex1_LYR 42 Dpekieellkkgre 55
                   ++++ +l+ +g++
    EEA19571.1 80 QFYQLDRLVVEGQK 93
                  57889999999998 PP

>> Complex1_LYR_2  Complex1_LYR-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.3   2.8   1.6e-09   9.6e-06       1      62 [.      15      77 ..      15     101 .. 0.81

  Alignments for each domain:
  == domain 1  score: 26.3 bits;  conditional E-value: 1.6e-09
  Complex1_LYR_2  1 vlsLYrrllrelrel.ppelrslgdayvraefrrhkhlk.npeeialflknqreYaellerynp 62
                    v+sL+r+l+r+  +    + r++ +++ r++fr+ ++++ ++ +i++f++     + +++r+  
      EEA19571.1 15 VRSLFRALMRQSSQFsNYNFREYARRRTRDAFRE-HQKEgEERKIQEFIQDGLKNLRMMKRQTV 77
                    79**********553499****************.67886777*******************44 PP

>> NA37  37-kD nucleoid-associated bacterial protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.1   8.7e-07    0.0052     180     238 ..      10      67 ..       6      98 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 8.7e-07
        NA37 180 dskkqtkkllkavedfakkeeldkaekqelrkrvveylkeqleegesvdleelaeelfk 238
                 d+++q++ l +a+ +  +++ + +  +++ r+r++++++e+ +ege+ +++e+++   k
  EEA19571.1  10 DTAFQVRSLFRALMRQSSQFSNYNFREYA-RRRTRDAFREHQKEGEERKIQEFIQDGLK 67 
                 66777777777777777777777776776.***********************998766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (113 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       891  (0.049696); expected 358.6 (0.02)
Passed bias filter:                      424  (0.0236488); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.41
# Mc/sec: 830.50
//
Query:       EEA19572.1  [L=583]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (583 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       625  (0.0348597); expected 358.6 (0.02)
Passed bias filter:                      275  (0.0153383); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.41
# Mc/sec: 4258.99
//
Query:       EEA19573.1  [L=329]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      2e-91  306.1  12.9    2.6e-91  305.8  12.9    1.0  1  Mg_trans_NIPA  Magnesium transporter NIPA
     0.0059   16.8   5.2     0.0059   16.8   5.2    3.8  3  EamA           EamA-like transporter family


Domain annotation for each model (and alignments):
>> Mg_trans_NIPA  Magnesium transporter NIPA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  305.8  12.9   2.9e-95   2.6e-91       4     293 ..       4     291 ..       2     293 .. 0.97

  Alignments for each domain:
  == domain 1  score: 305.8 bits;  conditional E-value: 2.9e-95
  Mg_trans_NIPA   4 liGvlLavssslfigssfilkkkgllrlarkgevrageGGyaylkevlWwaGlltmavGeaanfaayafaPatLvtPLGalsvivsavlasllLke 99 
                    +iG++Lav++s+ igss+++ kk+l++ + +        G+ y++++lWw+G +t+++Ge  n aayafaPa+LvtPLGalsv++ avl  ++L e
     EEA19573.1   4 FIGLTLAVLASVAIGSSYVITKKSLIQSSDRHGYDG--EGFRYIQNPLWWCGTITLVIGELMNTAAYAFAPAVLVTPLGALSVLIGAVLGAYFLSE 97 
                    68************************9987763333..69******************************************************** PP

  Mg_trans_NIPA 100 kLkllgllGcllailGstvlvihaPkeeeieslkevadllvdpaflvyvilvvvvvlvlilyveprkGktnilvyitlcsllgsltvisvkalgia 195
                    +L+++g +Gc  ++lGs++lv+haP  +ei++++ev dl+++p fl+y   v+  +l  i  ++pr G+ n ++y+ +csl+gs++v+svka gia
     EEA19573.1  98 ELNTVGRVGCANCLLGSILLVLHAPADREIHTIDEVLDLATQPLFLAYLLFVILYTLYAINRLAPRSGRINPVIYMSICSLVGSVSVMSVKAFGIA 193
                    ************************************************************************************************ PP

  Mg_trans_NIPA 196 ikltlaGkaqlkyalawilllvlvicvvlqinyLnkaldifntsivtPvyyvlfttlvivasailfkefleasvddvlgelsGfllvllgvfllha 291
                    +klt++G++q++++ ++++l+vlv++  +q +yLnka+ +f++ +v  +yyv f+t +i as+il++  +  +  ++++ ++Gfll +++v ll+ 
     EEA19573.1 194 VKLTFEGNNQFTHPSTYVFLVVLVVTTLTQTHYLNKAMSVFSAYLVNAMYYVGFATCTISASMILYQGLNTHDPTEIISLICGFLLEFVSVALLTI 289
                    **********************************************************************************************98 PP

  Mg_trans_NIPA 292 tr 293
                     r
     EEA19573.1 290 SR 291
                    77 PP

>> EamA  EamA-like transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    3.5   0.2    0.0082        74       2      25 ..       5      28 ..       4      33 .. 0.89
   2 !   16.8   5.2   6.6e-07    0.0059      71     136 ..      53     118 ..      48     119 .. 0.95
   3 ?   -5.4  11.0         2   1.8e+04       4     133 ..     145     278 ..     142     288 .. 0.62

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.0082
        EamA  2 lgillallaalfwaiyfvlskill 25
                +g+ la+la++  ++++v++k+ l
  EEA19573.1  5 IGLTLAVLASVAIGSSYVITKKSL 28
                7999****************9975 PP

  == domain 2  score: 16.8 bits;  conditional E-value: 6.6e-07
        EamA  71 gllgtvlafllffyalkktsasnaslitslePvftlilsvlllgekltlkqllgivlillGvllil 136
                 g++  v++ l+ + a    +a  ++++ +l++++ ++l++++l e l+    +g++ +llG +l++
  EEA19573.1  53 GTITLVIGELMNTAAYAFAPAVLVTPLGALSVLIGAVLGAYFLSEELNTVGRVGCANCLLGSILLV 118
                 788999********************************************************9987 PP

  == domain 3  score: -5.4 bits;  conditional E-value: 2
        EamA   4 illallaalfwaiyfvlskillrkvspltltfvrfliagilllii.allkegkl.....aklslkdwllllllgllgtvlafllffyalkktsasnasl 96 
                 +ll+++   ++ai+ ++ + +  +++p+ +  + +l++++ ++ + a+  + kl     +++++ +   +l++ ++ t+     +++a++  sa  +  
  EEA19573.1 145 YLLFVILYTLYAINRLAPRSG--RINPVIYMSICSLVGSVSVMSVkAFGIAVKLtfegnNQFTHPSTYVFLVVLVVTTLTQTHYLNKAMSVFSAYLVNA 241
                 556666666666666666554..7777766666666666666444333333333343433555555444444444555555567789999999998888 PP

        EamA  97 itslePvftlilsvlllgekltlkqllgivlillGvl 133
                 + ++  +  +i ++ +l + l+  +   i+  ++G l
  EEA19573.1 242 MYYVGFATCTISASMILYQGLNTHDPTEIISLICGFL 278
                 8888888888888888877777776666666666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (329 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       939  (0.0523733); expected 358.6 (0.02)
Passed bias filter:                      427  (0.0238162); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2242.26
//
Query:       EEA19574.1  [L=865]
Description: histone-lysine N-methyltransferase (Ash1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-13   51.7   0.3    1.3e-13   51.7   0.3    3.7  3  SET       SET domain
    2.4e-08   33.9   7.9    2.4e-08   33.9   7.9    1.9  2  AWS       AWS domain


Domain annotation for each model (and alignments):
>> SET  SET domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   3.9      0.96   8.6e+03      52      95 ..     175     234 ..      73     309 .. 0.56
   2 !   51.7   0.3   1.4e-17   1.3e-13       1     169 []     519     624 ..     519     624 .. 0.91
   3 ?   -1.9   0.7      0.42   3.8e+03      61      76 ..     733     748 ..     652     826 .. 0.55

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 0.96
                 X...........HHHHHHHTTSSHHHHHHHHHHHHHHHHHHTHHHHHHHXTTTS.....X CS
                 x...........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....x RF
         SET  52 t...........kelakasastllqklakdqkqaekedtdaalkasskaesdln.....a 95 
                 +           +e+a+++++ + ++ ++d++ +  + +++ +k+   + +d+      +
  EEA19574.1 175 SqttlmrdavdtDEQAHLATPVSKRSEEEDEAPRRRSLRARTVKEDDHKSNDKGnteanM 234
                 122233334423444444444444444444444444444444444433333333333221 PP

  == domain 2  score: 51.7 bits;  conditional E-value: 1.4e-17
                 SCEEEESSXBXTTXEEEEEE.ECCEECHHHHHHHHHH.......HTEEEEEXGGXXGGSXHHHHHHHTTSSHHHHHHHHHHHHHHHHHHTHHHHHHHXT CS
                 xxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         SET   1 GrGvfAtedIpkgeficeyp.eeiiltkdeadksele.......aylfslpeapknlaftkelakasastllqklakdqkqaekedtdaalkasskaes 91 
                 G+Gv++++ ++++++i+ey  e  i+t++e+++++ +       +yl+  +                                                
  EEA19574.1 519 GYGVRSNRTFEPNQIIVEYTgE--IITQNECERRMRSvyknnecYYLMYFD------------------------------------------------ 567
                 9*******************77..99999999999999*****98888888................................................ PP

                 TTSXXXHCCCCCHCCCHEEEETEEEEEECCCGTTGGGCEEXSSSSEEEEEEEETTSSEEEEEE.SSXBXTTEEEEEXTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxx RF
         SET  92 dlnaskpeagafsaiagysidaralksgngagplarflNHsCdpNcnltvqnvlrgprvavfA.trdIkkGeEltidYg 169
                                 +++ida+    g+ a    rf+NHsC pNc ++   v + pr+a+fA  r I  GeElt+dY+
  EEA19574.1 568 ---------------QNMIIDAT---RGSIA----RFVNHSCAPNCRMEKWTVGGKPRMALFAgDRGIMTGEELTYDYN 624
                 ...............78899977...89999....***********8887777**********5599***********7 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 0.42
                 TSSHHHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxx RF
         SET  61 stllqklakdqkqaek 76 
                 +  ++k++k+ k   k
  EEA19574.1 733 NVTVTKATKTSKSTTK 748
                 2222222233333333 PP

>> AWS  AWS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.9   7.9   2.7e-12   2.4e-08       3      37 ..     460     494 ..     459     495 .. 0.95
   2 ?   -4.5   1.4         2   1.8e+04      24      29 ..     635     640 ..     634     643 .. 0.76

  Alignments for each domain:
  == domain 1  score: 33.9 bits;  conditional E-value: 2.7e-12
         AWS   3 epsgcgsdCiNRmlliECteetCpcGerCqNqrfq 37 
                 e+ gc++dC NR +++EC++  C+ G +C N+ f+
  EEA19574.1 460 EETGCDEDCQNRFMFYECDSSNCRVGPNCGNRSFE 494
                 789*****************************997 PP

  == domain 2  score: -4.5 bits;  conditional E-value: 2
         AWS  24 tCpcGe 29 
                  C+cG+
  EEA19574.1 635 QCRCGA 640
                 599996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (865 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1772  (0.0988343); expected 358.6 (0.02)
Passed bias filter:                      254  (0.014167); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.84u 0.29s 00:00:01.12 Elapsed: 00:00:00.47
# Mc/sec: 5533.37
//
Query:       EEA19575.1  [L=630]
Description: DHHC zinc finger membrane protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-34  118.1   5.7    2.7e-34  118.1   5.7    1.6  2  DHHC      DHHC palmitoyltransferase
     0.0069   16.1   0.9     0.0069   16.1   0.9    2.1  2  Yip1      Yip1 domain


Domain annotation for each model (and alignments):
>> DHHC  DHHC palmitoyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.3       1.1     1e+04      87      87 ..     344     344 ..     311     361 .. 0.48
   2 !  118.1   5.7     3e-38   2.7e-34       6     133 ..     412     537 ..     409     538 .. 0.94

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 1.1
        DHHC  87 a 87 
                 +
  EEA19575.1 344 I 344
                 1 PP

  == domain 2  score: 118.1 bits;  conditional E-value: 3e-38
        DHHC   6 kfCstcniykpprskHcrvCnrcvlrfDHhCpwlnnciGerNykyFllfllylllllilalvlllialvklveeekkseflavtllkkllsilllvlsl 104
                 k+C+tcni++ppr++HcrvC++cv   DHhC+wlnnc+G+rNy+yF+ f+ + ++l+++ l ++l +++ + + ++ s+ + +++    + + ++++ +
  EEA19575.1 412 KYCKTCNIWRPPRCYHCRVCDNCVETLDHHCVWLNNCVGRRNYRYFFGFVSSATILALFLLGASLAHVLLYQQRQHISFGESISKWR--VPFAMVIYGA 508
                 8************************************************************99999999999999998888777665..89999999** PP

        DHHC 105 lfllllgllllfhlylilrnlTtieamkk 133
                 l++   ++l ++hl+l++r+ Tt+e++++
  EEA19575.1 509 LAFPYPAALWFYHLWLVARGETTREYLNS 537
                 *************************9985 PP

>> Yip1  Yip1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.8     0.018   1.6e+02      27      74 ..     316     357 ..     303     364 .. 0.60
   2 !   16.1   0.9   7.7e-07    0.0069      30      89 ..     464     527 ..     448     536 .. 0.73

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.018
        Yip1  27 lllalltlllgllaslnlgqtlasgeevqgltlssllgaiiggylgll 74 
                  +l++l++ l+l++s  +++   +     + +  +++g+i++ ++ ++
  EEA19575.1 316 GILIVLPVTLFLAYS--APWLWHNV----SPAIPIIFGYIFYVCFSSF 357
                 577888888888888..55555555....3334444444444444333 PP

  == domain 2  score: 16.1 bits;  conditional E-value: 7.7e-07
        Yip1  30 alltlllgllas......lnlgqtlasgeevqgltlssllgaiiggylglllgllllalllhliak 89 
                 a++ +l++l as       + +q ++ g  ++  ++  +++++i+g+l+++ +++l+ ++l+l+a+
  EEA19575.1 464 ATILALFLLGASlahvllYQQRQHISFG--ESISKWRVPFAMVIYGALAFPYPAALWFYHLWLVAR 527
                 3344444444446666555556666666..788******************************999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (630 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       681  (0.0379832); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.33s 00:00:00.93 Elapsed: 00:00:00.48
# Mc/sec: 3963.29
//
Query:       EEA19576.1  [L=465]
Description: srpk, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      1e-12   48.0   0.0      2e-10   40.5   0.0    2.4  3  Pkinase      Protein kinase domain
    0.00077   19.5   0.4     0.0036   17.3   0.3    2.0  2  APH          Phosphotransferase enzyme family
  ------ inclusion threshold ------
       0.07   12.4   0.0       0.25   10.6   0.0    1.8  2  Pkinase_Tyr  Protein tyrosine kinase


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.5   0.0   3.4e-14     2e-10       1     132 [.      77     215 ..      77     224 .. 0.82
   2 ?   -3.0   0.0      0.64   3.8e+03     135     154 ..     274     293 ..     269     303 .. 0.69
   3 !    5.0   0.0    0.0023        14     206     264 .]     376     446 ..     347     446 .. 0.67

  Alignments for each domain:
  == domain 1  score: 40.5 bits;  conditional E-value: 3.4e-14
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHS..CTTB--EEEEEEE....SSEEEEEEE--TTEBHHHHHH..H CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklk..hpnivrlyevfee....kdelylvleyveggeladlle..r 91 
                 y+  +klG G +++   a +  +g+ vA+K+   e+ + ++e +vl+ ++  +++    p + +++++f+      ++++l+++ ++ + l+++ e   
  EEA19576.1  77 YVIAHKLGFGRSATTWLAEDIVNGRLVALKISTAESVDRMHEMEVLSRLAKAESSLpgKPIVQNILDSFTVsgpnGTHRCLITDAARLN-LNEVKEypY 174
                 56789*******************************99999955555544444333333333346666665566799*********966.999999888 PP

                 HSS--HHHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEE CS
     Pkinase  92 kgslseeeakkiakqilegleylHskgiiHrDlKpeNiLid 132
                 ++ l    a+ ia+q+l g++ +Hs+gi+H Dl   N+L++
  EEA19576.1 175 HRLLHLPAARAIAAQLLLGVQLIHSQGIVHGDLHLGNMLLQ 215
                 999************************************98 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.64
                 TEEEE-SGTTSEESSSSCSB CS
     Pkinase 135 gelKitDFGlakelessskl 154
                 + + i+DFG a   ++++++
  EEA19576.1 274 APITISDFGEAFDPQTTKQY 293
                 558899***98776666544 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.0023
                 HHHHHHTHHHHHHHCTSHH...HHHTTS................-HHHHHHHHHHT-SSGCCSTTHHHHHTSGGG CS
     Pkinase 206 vekeldqlekilkilgetkeklpeasei................seeakdllkkllkkdpkkRltaeellqhpyl 264
                 v+++l+q    + i    + +++ +++i                +  ++ ++k +l  +p kR t++e+++ +++
  EEA19576.1 376 VKEDLRQW---YGITS-RDWDTRFDENIrkprerngfelfsadeEAAFRGMMKLILVLEPGKRATIDEVVKCEWM 446
                 33344442...22221.122222222225555668888899888888999*********************9997 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.0      0.24   1.4e+03       5      52 ..      83     130 ..      80     143 .. 0.72
   2 !   17.3   0.3   6.1e-07    0.0036     135     182 ..     171     217 ..     145     223 .. 0.68

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.24
                 E--.SSCEEEEEEETT.--EEEEEE-TTS-HHHHHHHHHHHHHHHHTT- CS
         APH   5 lsggasnrtylvttpa.gryvlrrnpparaaeeirrevallrlLakagv 52 
                 l+ g s  t+l ++   gr+v   +++a +  +   e ++l  Laka+ 
  EEA19576.1  83 LGFGRSATTWLAEDIVnGRLVALKISTA-ESVDRMHEMEVLSRLAKAES 130
                 6667788888888877787774444555.47777788889999999976 PP

  == domain 2  score: 17.3 bits;  conditional E-value: 6.1e-07
                 CCCGCCTCCHHHHHHHHHHHHHHHH--SSS-EEEE-SS-SGGGEEEC.. CS
         APH 135 rllaselldlleeleeqvlaalaallpgelptvllHgDlhpgNllvd.p 182
                  ++ ++ll  l ++++ ++a+l+  ++   +++++HgDlh+gN+l++ p
  EEA19576.1 171 EYPYHRLLH-LPAARA-IAAQLLLGVQLIHSQGIVHGDLHLGNMLLQlP 217
                 444444444.444455.55555555555899**************9854 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   4.2e-05      0.25      29     138 ..     101     216 ..      78     225 .. 0.63
   2 ?   -1.5   0.0       0.2   1.2e+03     140     170 ..     274     300 ..     268     310 .. 0.68

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 4.2e-05
                  EEEEEEEEST.TSSHHHHHHHHH.HHHHHHTS.-BTTB--EEEEEE....SSSSEEEEEE--TTEBHHHHHHHTCTTTSBHHHHHHHHHHHHHHHHHH CS
  Pkinase_Tyr  29 vkVavKtlke.eateeekeelle.eakimkkl.khpnivkllgvct....keepllivteyvkgGdLlkfLrkkekekltlkdllsfalqvAkGmeyL 119
                    Va+K+ ++ + ++ ++ e+l+  ak  ++l  +p + ++l   t    ++ + +++t+ ++  +L++  +   ++ l+l     +a+q+  G++ +
   EEA19576.1 101 RLVALKISTAeSVDRMHEMEVLSrLAKAESSLpGKPIVQNILDSFTvsgpNGTHRCLITDAARL-NLNEVKEYPYHRLLHLPAARAIAAQLLLGVQLI 197
                  5567776643033333333333313444444433333334444444333444557788777655.455555555667889999999************ PP

                  HHTTEEEST-SGGGEEEEE CS
  Pkinase_Tyr 120 eskklvHrdlaarNvLlse 138
                  +s+ +vH dl   N+Ll+ 
   EEA19576.1 198 HSQGIVHGDLHLGNMLLQL 216
                  ****************985 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.2
                  TEEEE-STTTHEETTTSSEEEETTSSTSGGG CS
  Pkinase_Tyr 140 kvvkisDfGLardiekddeyvkkeeaklpvk 170
                    + isDfG a d +++++y++    ++p+ 
   EEA19576.1 274 APITISDFGEAFDPQTTKQYTA----HTPLL 300
                  5689*****9988866666654....44444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (465 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       379  (0.0211389); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 2958.18
//
Query:       EEA19577.1  [L=159]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.083   12.8   0.2       0.24   11.3   0.0    1.8  2  RHH_5     CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5


Domain annotation for each model (and alignments):
>> RHH_5  CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.1      0.27   4.8e+03       9      18 ..      44      53 ..      44      54 .. 0.58
   2 ?   11.3   0.0   1.3e-05      0.24       5      23 ..     138     156 ..     138     157 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.27
       RHH_5  9 PeelleeLee 18
                P+++ e Lee
  EEA19577.1 44 PAKVEESLEE 53
                5666666665 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 1.3e-05
       RHH_5   5 nvtLPeelleeLeewAdee 23 
                 nvtLPe+l e++ ++ +ee
  EEA19577.1 138 NVTLPEDLHERFNKYGKEE 156
                 8***********9988876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (159 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       362  (0.0201908); expected 358.6 (0.02)
Passed bias filter:                      329  (0.0183502); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.37u 0.24s 00:00:00.61 Elapsed: 00:00:00.38
# Mc/sec: 1264.37
//
Query:       EEA19578.1  [L=942]
Description: protein mannosyltransferase 1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.7e-78  262.2  18.0    8.8e-78  261.3  18.0    1.5  1  PMT       Dolichyl-phosphate-mannose-protein mannosyltransfer
    1.7e-67  226.9   9.4    1.7e-67  226.9   9.4    2.2  2  PMT_4TMC  C-terminal four TMM region of protein-O-mannosyltra
    2.1e-48  164.7   0.1      5e-48  163.4   0.1    1.6  1  MIR       MIR domain


Domain annotation for each model (and alignments):
>> PMT  Dolichyl-phosphate-mannose-protein mannosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  261.3  18.0   1.5e-81   8.8e-78       3     243 ..      71     318 ..      69     320 .. 0.95

  Alignments for each domain:
  == domain 1  score: 261.3 bits;  conditional E-value: 1.5e-81
         PMT   3 ltllallirlwrlslpnsvvfdevhfgkfasdYlehsffmdvhpplgkmllalggyLagkdgnftfesigaeyypenvpyvslRlfsallgslivplvy 101
                 ltl a+++rl r+++p svvfdevhfg fa +Y++++ffmdvhppl+k+l+ l+++Lag++g+f f +ig +y   +vpyv++Rl++a+lg+l+vpl++
  EEA19578.1  71 LTLGAAAVRLFRIYQPSSVVFDEVHFGGFATKYIKGTFFMDVHPPLAKLLITLAAWLAGFQGDFSFSDIGMDYLEPGVPYVAMRLLPAILGVLTVPLMF 169
                 5777899******************************************************************9999********************** PP

         PMT 102 ltllelgfskltallaallvllenslitlsryilldspLlfftllsmyclvkfe......rkapfsrswwlwllltgvalglavsvKwvglftvllvgl 194
                 ltl+  g +  t+++ a+lv+++n+l t+sr+illdspL+fft+l+ +++  f        ++ f  +ww+wl+l g++lg ++svKwvglft++++g+
  EEA19578.1 170 LTLKATGCRTSTSVMGAVLVTFDNALTTQSRFILLDSPLIFFTALTALSFACFTnqheqgPSKAFKGAWWFWLVLSGLSLGATLSVKWVGLFTTAWLGS 268
                 ******************************************9987766666666658884466*********************************** PP

         PMT 195 lliwelwqllgdkslllksi.vkhllaralaliviPvtlylavftvhfwl 243
                 ++i +lw llgd    + +  +kh++ar+++l+viP+ +y+a+f vhf  
  EEA19578.1 269 ITILQLWVLLGDSNTVTPRLwFKHFFARFFCLVVIPLGFYIAMFGVHFLC 318
                 ***********99999998889**************************76 PP

>> PMT_4TMC  C-terminal four TMM region of protein-O-mannosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   6.0      0.79   4.7e+03       1     111 [.     210     317 ..     210     321 .. 0.70
   2 !  226.9   9.4   2.9e-71   1.7e-67       1     199 []     566     764 ..     566     764 .. 0.95

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 0.79
    PMT_4TMC   1 FlkkflelqkamltsnnalteshpyaSepyeWplllrgisywtkneekkqiyllGNpvlwwlstiallvfvllll.alllrrqrgvkdleeeetr..ll 96 
                 F++ +  l  a +t + +  +s  ++ +++ W++l +g+s+         +  +G   + wl++i++l +++ll+  + ++ +  +k++   +    ++
  EEA19578.1 210 FFTALTALSFACFTNQHEQGPSKAFKGAWWFWLVL-SGLSLGAT----LSVKWVGLFTTAWLGSITILQLWVLLGdSNTVTPRLWFKHF-FARFFclVV 302
                 7888888999999988888889**********865.78888765....57889999999999999999888888744444444444444.122113455 PP

    PMT_4TMC  97 nsglflllgwalhyl 111
                 + ++f++  + +h+l
  EEA19578.1 303 IPLGFYIAMFGVHFL 317
                 556677777777776 PP

  == domain 2  score: 226.9 bits;  conditional E-value: 2.9e-71
    PMT_4TMC   1 FlkkflelqkamltsnnalteshpyaSepyeWplllrgisywtkneekkqiyllGNpvlwwlstiallvfvllllalllrrqrgvkdleeeetr.llns 98 
                 Fl kflelq++m+t+n++ltesh ++S+p +Wp+llrgi++w+k+++  q+yl+GNp++ww+st+++++++++ ++ +lr+qr+++d+++ + + + ++
  EEA19578.1 566 FLGKFLELQRVMWTTNAGLTESHAWDSRPPSWPTLLRGINFWGKDHR--QVYLFGNPLIWWSSTATIALYIAFKGLAVLRWQRSCNDYKNVNFKrFDYE 662
                 999*****************************************988..***************************************4444446**** PP

    PMT_4TMC  99 glflllgwalhylPfflmgRvlflhhYlpAllfailllaalldfllkslkkslkkk.klvklivvvvllvlviavFiffspltyGlpgtseevkklkwl 196
                 +++ +lgwa+hy+Pfflm+R+lflhhYlpAl+fai++l++++df+l++++  +  k ++v+  +++++l+l+++vF+++splty++p+t+++++++k+l
  EEA19578.1 663 VGTTVLGWAFHYFPFFLMARQLFLHHYLPALYFAIMALSQTFDFVLNRVQLPVIGKrSIVGSGLIATFLALSVGVFVIYSPLTYANPWTTDACQSVKLL 761
                 **********************************************8777655444699**************************************** PP

    PMT_4TMC 197 ssW 199
                 +sW
  EEA19578.1 762 DSW 764
                 *** PP

>> MIR  MIR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  163.4   0.1   8.3e-52     5e-48       2     184 ..     366     542 ..     365     553 .. 0.96

  Alignments for each domain:
  == domain 1  score: 163.4 bits;  conditional E-value: 8.3e-52
         MIR   2 yLkggdvvRLfHshqdeyltiseqqqkqevflritlypsadaanssraLWeievvqkd...............awrgglikwgkvyRlkHlaTgryLas 85 
                 yL         Hsh ++y+t+s+qqq       +tlyp++d++n     + +e+++++               +++ ++i +g+v+Rl+Hl+T+r+++s
  EEA19578.1 366 YL---------HSHAHMYPTGSQQQQ-------VTLYPHKDENNV----FLLENQTQPvgadgaeiegpmawdNTTAEYIYDGAVLRLYHLTTHRRIHS 444
                 55.........***************.......************....*******************99666669*********************** PP

         MIR  86 eeekksplseseddqkevsayglegfegd.nDk..veifekksttgmksaklvprdsyvrlqHvvtgcwLhstsvklkkekfekvqqkvicakekedke 181
                 ++e ++p++++ d+q+evsayg+egf+gd nD   vei++++s+  +++++l+++++++rl+Hv+tgc+L+s++vkl+++ f+  qq+v+cak+++ ++
  EEA19578.1 445 HDE-RAPITDA-DWQNEVSAYGYEGFPGDaNDLfrVEIVKSESDGEEAKKRLRTIQTKFRLIHVMTGCALFSHKVKLPDWAFD--QQEVTCAKQGTLPN 539
                 ***.*****88.*****************8888**************************************************..************99 PP

         MIR 182 ala 184
                 +l+
  EEA19578.1 540 SLW 542
                 998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (942 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       611  (0.0340789); expected 358.6 (0.02)
Passed bias filter:                      386  (0.0215294); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.71u 0.28s 00:00:00.99 Elapsed: 00:00:00.44
# Mc/sec: 6454.75
//
Query:       EEA19579.1  [L=600]
Description: pre-mRNA splicing factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      1e-57  195.5  12.6    2.4e-57  194.3  12.6    1.6  1  PRP21_like_P     Pre-mRNA splicing factor PRP21 like protein
    9.8e-39  131.1   1.5    1.7e-19   69.5   0.0    2.5  2  Surp             Surp module
     0.0045   16.5   0.2       0.01   15.4   0.2    1.6  1  zf_UBZ           Ubiquitin-Binding Zinc Finger
  ------ inclusion threshold ------
        7.1    6.9  10.2         10    6.4   2.5    2.8  2  E7               E7 protein, Early protein


Domain annotation for each model (and alignments):
>> PRP21_like_P  Pre-mRNA splicing factor PRP21 like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  194.3  12.6   5.4e-61   2.4e-57       2     217 .]     211     466 ..     210     466 .. 0.86

  Alignments for each domain:
  == domain 1  score: 194.3 bits;  conditional E-value: 5.4e-61
  PRP21_like_P   2 lkdkqkileralkraewekqkekeeqkkeeeeeeeklafasiDWqdFvvvetieFdd.deleelpkPltleelkarsleqkskal............ 85 
                    k+k++il+ra++raew k++e+++qkkeeeee+e++++a+iDW+dF+vvet+ F++ d++ elp+P++l +l+++sleqk +++            
    EEA19579.1 211 TKNKYHILDRAKQRAEWVKYQEQQKQKKEEEEEKERIEYAQIDWHDFAVVETVLFTEaDDQIELPPPASLGDLQSASLEQKAAMSlnplrieeampt 307
                   689********************************************************************************************** PP

  PRP21_like_P  86 .................................eeaeaetdvemevdeeeeeeseekiekkskesavseepalakae.kkmkikadyesrlkkrkns 148
                                                      + +  ++++  ++eeee++ ++ +  +  +++s  +a aka+  +m+i+ dy++r+++r+++
    EEA19579.1 308 deaepvyynaypmqqvgptpqfqqapipaeqqqPFQLPTVPTPISAANEEEERRIRERA--EARDQASAAQAAAKAQpPSMRIRSDYVPRAQSRRQQ 402
                   ****************************9643311222223344444444444444333..334445555555555559**************9999 PP

  PRP21_like_P 149 katkekkkakcpitgeliPedeleeHmrieLlDPrykeqkdklvekkskesslltddevaenlkrlakk 217
                   +a+     a cp++ + iP  el++Hmrie+lDPr+keq++k+  +++++ ++l + +va nlkrla++
    EEA19579.1 403 NAAV---TALCPNCHQQIPVAELDQHMRIEMLDPRWKEQREKA--ESRAAHTNLITTDVAGNLKRLASQ 466
                   9966...569*******************************86..999******************985 PP

>> Surp  Surp module
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.5   0.0   3.8e-23   1.7e-19       1      52 [.      35      85 ..      35      86 .. 0.94
   2 !   60.3   0.5   2.9e-20   1.3e-16       1      53 []     134     185 ..     134     185 .. 0.98

  Alignments for each domain:
  == domain 1  score: 69.5 bits;  conditional E-value: 3.8e-23
                HHHHHHHHHHHTT-S.SHHHHHHHH.T--TTSGGGSTT.STTHHHHHHHHHH CS
        Surp  1 leiIkktAqfVarnGkeFeqklrerernnpqFaFLkdpdhpyhayYrwrvde 52
                + i++ktA + arnG+ Feq++re+e++np+F+FL++  ++y ayY wr+de
  EEA19579.1 35 RAIVEKTAGYAARNGPVFEQRIREKEQSNPKFSFLSPG-DAYAAYYLWRLDE 85
                679********************************666.***********98 PP

  == domain 2  score: 60.3 bits;  conditional E-value: 2.9e-20
                 HHHHHHHHHHHTT-S.SHHHHHHHH.T--TTSGGGSTT.STTHHHHHHHHHHH CS
        Surp   1 leiIkktAqfVarnGkeFeqklrerernnpqFaFLkdpdhpyhayYrwrvdey 53 
                 le++k+tA fVa+ Gk F + l +re +n qF+FL+++ h+++++++++vd+y
  EEA19579.1 134 LEVVKLTALFVAKRGKSFMTSLSQREARNFQFDFLRPQ-HSLYQFFTRLVDQY 185
                 689********************************999.*************9 PP

>> zf_UBZ  Ubiquitin-Binding Zinc Finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.2   2.3e-06      0.01       4      20 ..     409     425 ..     406     426 .. 0.91

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 2.3e-06
      zf_UBZ   4 lCerCgkeipeselqEH 20 
                 lC+ C+++ip++el++H
  EEA19579.1 409 LCPNCHQQIPVAELDQH 425
                 8**************** PP

>> E7  E7 protein, Early protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   1.0     0.013        56      16      39 ..     223     247 ..     191     266 .. 0.68
   2 ?    6.4   2.5    0.0023        10      52      78 ..     387     431 ..     344     434 .. 0.60

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.013
                 XXX--S-.-----XXXXXXXXXXXX CS
          E7  16 evldllc.eeelesedeeeeeedep 39 
                 + ++    +e++++++eeeee+++ 
  EEA19579.1 223 QRAEWVKyQEQQKQKKEEEEEKERI 247
                 4444444055555555556655533 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.0023
                 E..................EEEEXTTTXXEEEEEEEEXHHHHHHH CS
          E7  52 a..................vevaCprCeqklrlvvlateegirql 78 
                 +                  v++ Cp+C+q++ ++ l ++  i  l
  EEA19579.1 387 RirsdyvpraqsrrqqnaaVTALCPNCHQQIPVAELDQHMRIEML 431
                 0444444444444445555************99988888877766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (600 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1762  (0.0982765); expected 358.6 (0.02)
Passed bias filter:                      680  (0.0379274); expected 358.6 (0.02)
Passed Vit filter:                        74  (0.00412739); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.71u 0.31s 00:00:01.02 Elapsed: 00:00:00.48
# Mc/sec: 3723.38
//
Query:       EEA19580.1  [L=696]
Description: GDP/GTP exchange factor Sec2p, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.4e-28   97.9  19.9    2.4e-28   97.9  19.9    2.5  2  Sec2p      GDP/GTP exchange factor Sec2p
    3.4e-05   22.6  16.7    3.4e-05   22.6  16.7    2.0  2  Macoilin   Macoilin family
  ------ inclusion threshold ------
      0.014   15.6   1.0      0.045   14.0   1.0    2.0  1  DUF4276    Domain of unknown function (DUF4276)
        1.3    8.2   8.1        2.5    7.3   8.1    1.4  1  CorA       CorA-like Mg2+ transporter protein
        3.6    7.8  23.0       0.13   12.4   5.7    3.2  3  Fib_alpha  Fibrinogen alpha/beta chain family
        9.3    6.4  13.5         28    4.9   6.7    3.3  3  Med9       RNA polymerase II transcription mediator complex s


Domain annotation for each model (and alignments):
>> Sec2p  GDP/GTP exchange factor Sec2p
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.6      0.28   8.4e+02      51      73 ..     127     142 ..      99     157 .. 0.52
   2 !   97.9  19.9   8.1e-32   2.4e-28       2      91 ..     178     267 ..     177     268 .. 0.97

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 0.28
                 HHHHHHHHHTTHCHCCCHCTSSS CS
       Sec2p  51 kneklkeqLkeketlleslqeqL 73 
                   +  +++L+e+       +e L
  EEA19580.1 127 SLSATRQELEEA-------EERL 142
                 333333333333.......3332 PP

  == domain 2  score: 97.9 bits;  conditional E-value: 8.1e-32
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTHCHCCCHCTSSSSHHHHCTTTXXXXXXXXX CS
       Sec2p   2 lkeekkkreeaekekkklekEledLtasLFeeANkmVaaarkekealekkneklkeqLkeketlleslqeqLkeLkevlekmeeeseeqe 91 
                 l+ee++kr+ aekek+++e+Ele+Lta+LFeeANkmVaaa++e+ea+ekkne+l++q+k++e+l++s++eqL+eLk v+++m++ +++++
  EEA19580.1 178 LDEERAKRTVAEKEKREMEQELETLTAALFEEANKMVAAAKQEREAIEKKNEQLRAQIKDTEALVASQEEQLAELKAVIQEMNSARDDND 267
                 689*********************************************************************************999875 PP

>> Macoilin  Macoilin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.6  16.7   1.1e-08   3.4e-05     361     565 ..      23     268 ..       5     297 .. 0.71
   2 ?    1.6   1.9     0.026        79     279     336 ..     630     682 ..     563     693 .. 0.49

  Alignments for each domain:
  == domain 1  score: 22.6 bits;  conditional E-value: 1.1e-08
    Macoilin 361 ssknskkqklpaGkssaalkdaaenslpnnql........................................skkdalvrLeadikkLkaeLqasrqte 419
                 s+ n++k++ +aGk +++      ++ + n l                                        s  +    L ++++ L a+L ++ +++
  EEA19580.1  23 SRPNNHKRSQSAGKRTRSPARFLTKMKSTNALsdfnragrrlspagledlqesdfntlrdprmgstsdltgsSDSSHHPDLSSEVAALSAKLVQAINNQ 121
                 34444455555555555333333333233333233334444444444444444455555555566666665344444459******************* PP

    Macoilin 420 qelrskissltseerslkselqqlkkendllqtklhelvsakqkd.kqtlqqlekrLkeekearaslekqLae.ekkrkkeeeetaaravalaaasrse 516
                 ++l + +s+  +e  ++ + l +++ en++ ++ + + +  k+ d   ++ ++ + L+ee+ +r+ +ek  +e e+       +   +a  + aa+++e
  EEA19580.1 122 TNLDDSLSATRQELEEAEERLLEVESENEKYRAEISSGIMIKRSDvEAEILSMKQMLDEERAKRTVAEKEKREmEQELETLTAALFEEANKMVAAAKQE 220
                 *********9999999*******************998877777725689******************9765523344444444445666666666666 PP

    Macoilin 517 cteslkskkreleaeikkLekelklkeeqirelelkvqelrkykesekd 565
                 + e++ +k+++l a+ik  e  +  +eeq++el++ +qe++  +++++ 
  EEA19580.1 221 R-EAIEKKNEQLRAQIKDTEALVASQEEQLAELKAVIQEMNSARDDNDT 268
                 5.899999********************************998776554 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.026
    Macoilin 279 vdsklqekeymenkskskrlsksessgsesellveesvkskssssssssnknskkasa 336
                 + +++qe  + ++   +k+l ++  +++  +  +++++++++s ++    +n+++a++
  EEA19580.1 630 KVDNVQEVAHAADGEAEKQLRTD-LETTLPDASHSKESSESTSQHT----SNHEEAEN 682
                 22223333333333333333222.1111111111111111111111....11111111 PP

>> DUF4276  Domain of unknown function (DUF4276)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   1.0   1.5e-05     0.045      55     138 ..     177     277 ..     104     325 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1.5e-05
     DUF4276  55 liDlyal.....................dafkrveeleralkedidskgderfipyiqlhefEawlladpealkekseslsklkkirkefsnPenindg 132
                 ++D +++                       f++++++ +a+k++ ++ ++++ + + q++++Ea+  ++ e+l+e ++ +++++ +r+ +    ++ ++
  EEA19580.1 177 MLDEERAkrtvaekekremeqeletltaALFEEANKMVAAAKQEREAIEKKNEQLRAQIKDTEALVASQEEQLAELKAVIQEMNSARDDN----DTTPN 271
                 566666677777777743333334444333444555555555555555**************************4444444444444444....44445 PP

     DUF4276 133 pktaps 138
                 p tap+
  EEA19580.1 272 PSTAPT 277
                 666665 PP

>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   8.1   0.00085       2.5     108     226 ..     107     235 ..      79     240 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.00085
        CorA 108 pgellyrlldeivd..rlfellekleeeldeledel.....edstkkeilrelaqlrrrlvkl....rralapnrevlkrllakaddkllddedkeylr 195
                 ++ l ++l+++i++  +l++ l++  +el+e+e++l     e+++ + ++++ + ++r+ v+      +++++ +++  r +a +++ ++++e + +  
  EEA19580.1 107 VAALSAKLVQAINNqtNLDDSLSATRQELEEAEERLlevesENEKYRAEISSGIMIKRSDVEAeilsMKQMLDEERAK-RTVAEKEKREMEQELETLTA 204
                 556666677777652268999****************99888888888888888899886666544544555555555.77778*************** PP

        CorA 196 dlldelerllemlealrerleslqdtyssll 226
                  l +e+++++  +++ re +e+ ++++ +++
  EEA19580.1 205 ALFEEANKMVAAAKQEREAIEKKNEQLRAQI 235
                 *********************9999988877 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   5.6      0.08   2.4e+02      30     106 ..     100     176 ..      97     204 .. 0.70
   2 ?   12.4   5.7   4.5e-05      0.13      49     115 ..     194     260 ..     184     263 .. 0.88
   3 ?    0.9   0.5      0.16   4.8e+02      35      74 ..     647     687 ..     633     692 .. 0.74

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.08
                 CCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHH CS
   Fib_alpha  30 ekdvkkdlekleneleeisnstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirv 106
                 ++d++ +++ l  +l ++ n++++ ++  +++++ l+e+++   + ++  +k++ e+ + i+  +  + a++ ++++
  EEA19580.1 100 HPDLSSEVAALSAKLVQAINNQTNLDDSLSATRQELEEAEERLLEVESENEKYRAEISSGIMIKRSDVEAEILSMKQ 176
                 67888999999999999999999999999999999999998877767777777777776665555555554433333 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 4.5e-05
                 CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHH CS
   Fib_alpha  49 nstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvLqnvlesne 115
                 ++++e e+l+ ++ +  ++  + +k++ ++i+k +++l+ +i + ++ + +qe+++ +L+ v+++ +
  EEA19580.1 194 EMEQELETLTAALFEEANKMVAAAKQEREAIEKKNEQLRAQIKDTEALVASQEEQLAELKAVIQEMN 260
                 566778888888999999999999999************************************9876 PP

  == domain 3  score: 0.9 bits;  conditional E-value: 0.16
                 HHH.CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  35 kdl.ekleneleeisnstkeaeelvkeikdslrekqkskkd 74 
                 k+l ++le +l ++s+s++++e++++++++  +++++ ++d
  EEA19580.1 647 KQLrTDLETTLPDASHSKESSESTSQHTSNHEEAENNASED 687
                 55524799999999999999999999999887776666554 PP

>> Med9  RNA polymerase II transcription mediator complex subunit 9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.1     0.015        45      19      67 ..      98     143 ..      77     156 .. 0.78
   2 ?   -1.7   0.1       1.1   3.1e+03      49      62 ..     189     202 ..     163     208 .. 0.58
   3 ?    4.9   6.7    0.0094        28      21      67 ..     214     260 ..     194     264 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.015
        Med9  19 lsskdletktgelrhkLkkarelirelpgidrsveeqeaeieeleeqla 67 
                 ++  dl++++++l  kL +a   i++  ++d s     +e+ee ee+l 
  EEA19580.1  98 SHHPDLSSEVAALSAKLVQA---INNQTNLDDSLSATRQELEEAEERLL 143
                 67778888899999888865...88888899999999999999999885 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 1.1
        Med9  49 drsveeqeaeieel 62 
                 ++ + e+e+e+e+l
  EEA19580.1 189 EKEKREMEQELETL 202
                 45556666666665 PP

  == domain 3  score: 4.9 bits;  conditional E-value: 0.0094
        Med9  21 skdletktgelrhkLkkarelirelpgidrsveeqeaeieeleeqla 67 
                 +   +++  ++ +k ++ r++i+  + +  s+eeq+ae+++  +++ 
  EEA19580.1 214 VAAAKQEREAIEKKNEQLRAQIKDTEALVASQEEQLAELKAVIQEMN 260
                 5556777889999**************************99888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (696 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2344  (0.130738); expected 358.6 (0.02)
Passed bias filter:                      624  (0.0348039); expected 358.6 (0.02)
Passed Vit filter:                       115  (0.00641419); expected 17.9 (0.001)
Passed Fwd filter:                        45  (0.0025099); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.10u 0.36s 00:00:01.46 Elapsed: 00:00:00.55
# Mc/sec: 3806.19
//
Query:       EEA19581.1  [L=136]
Description: dsDNA-binding protein PDCD5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.7e-38  131.3  10.7      2e-38  131.1  10.7    1.0  1  dsDNA_bind  Double-stranded DNA-binding domain
     0.0076   16.8   0.5       0.01   16.4   0.4    1.3  1  DUF4615     Domain of unknown function (DUF4615)


Domain annotation for each model (and alignments):
>> dsDNA_bind  Double-stranded DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  131.1  10.7   2.2e-42     2e-38       1     111 []       9     122 ..       9     122 .. 0.90

  Alignments for each domain:
  == domain 1  score: 131.1 bits;  conditional E-value: 2.2e-42
                 XXXXXXXXXXXXXXXXXXXX...XXXX--SS..S--SSHHHHTTS--HHHHHHHHHHTTT-HHHHHHHHHHHHHHHH--SS-----HHHHHHHHHHHS- CS
  dsDNA_bind   1 irkarlaelqaqagsssgsggaseqqeqqqeaseeeakqaiLsqiLepeAreRLsrirlvkperaeavenrLiqlaqsGqlrskvteeqLkeLLeqvae 99 
                 ir+arla+lq++ g+++++  ++e qe+q++++e++++ +iL+qiL+p A++RL+rirlvk+ ra+++enrLi+laq+Gqlr+kvte+qLk+LL++vae
  EEA19581.1   9 IRRARLAQLQQRGGGRGAA-PSGEGQEDQRRQAEADRRATILNQILDPAAADRLGRIRLVKESRATDIENRLIMLAQTGQLRQKVTEDQLKDLLNAVAE 106
                 9**********99877664.4566667777778****************************************************************** PP

                 ....--XXXXX..XXX CS
  dsDNA_bind 100 ....kkketkivisrr 111
                     +++e+k+v+srr
  EEA19581.1 107 nsrkEEEEQKVVFSRR 122
                 875444459****997 PP

>> DUF4615  Domain of unknown function (DUF4615)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.4   1.1e-06      0.01      29      98 ..      59     124 ..      45     133 .. 0.75

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 1.1e-06
     DUF4615  29 ealkalktLksekaplvkKRqlmrttfGDYRakmaeeekkqlklaqsaikiaevasekkkskrvfvkksa 98 
                 + l  ++  k+++a  +  R +m + +G  R+k+ e++ k   l+++ ++ ++  +e++++k vf +++ 
  EEA19581.1  59 DRLGRIRLVKESRATDIENRLIMLAQTGQLRQKVTEDQLK--DLLNAVAENSR--KEEEEQKVVFSRRKG 124
                 556789999***************************9999..44444444443..344444457888775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (136 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1120  (0.0624686); expected 358.6 (0.02)
Passed bias filter:                      570  (0.0317921); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 947.46
//
Query:       EEA19582.1  [L=287]
Description: Coenzyme Q (ubiquinone) biosynthesis protein Coq4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.7e-96  320.4   0.0    5.6e-96  320.1   0.0    1.1  1  Coq4      Coenzyme Q (ubiquinone) biosynthesis protein Coq4
  ------ inclusion threshold ------
      0.073   13.3   0.2       0.12   12.5   0.2    1.3  1  DUF2236   Uncharacterized protein conserved in bacteria (DUF2


Domain annotation for each model (and alignments):
>> Coq4  Coenzyme Q (ubiquinone) biosynthesis protein Coq4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  320.1   0.0  6.3e-100   5.6e-96       1     221 []      41     261 ..      41     261 .. 0.99

  Alignments for each domain:
  == domain 1  score: 320.1 bits;  conditional E-value: 6.3e-100
        Coq4   1 yeghvplslleklllavgsaiaalvdpergdlvaalgettglpa.lerlrekmlsdeeGrriLkerpritsetldleklkklpentlGraYakfleken 98 
                 y+ghvpl+ +e+ +la+gsa+++l++p+r+dl+aalge+t++p+ ++rlr++mls+++GrriL++rpritsetl+l +l++lpen++G +Yak+l+ke+
  EEA19582.1  41 YPGHVPLNRIERGVLAIGSAFGSLINPYRHDLIAALGEATATPYfIYRLRDAMLSNPTGRRILRDRPRITSETLKLPYLRNLPENSVGWTYAKWLDKEG 139
                 99***************************************9999****************************************************** PP

        Coq4  99 vspdtRapvryiddeelaYvmqRyrevHDflHvllglptnvegEiavkafefaqtglpmallsalfgplrlsskererlleeylpwalragkkakelln 197
                 v+pd+R++v+yiddee+aYvmqRyre+HDf+H+++glpt vegE+a+kafef++t lpm++ls l++ +rl+++erer+++ +lpwa+r+g +++el+n
  EEA19582.1 140 VTPDSRDSVQYIDDEECAYVMQRYRECHDFYHAVTGLPTMVEGELALKAFEFLNTVLPMTGLS-LAAVVRLKPAERERFFKLHLPWAVRSGLSSEELIN 237
                 ***************************************************************.99********************************* PP

        Coq4 198 vywEeeletdleelrkelgiekpp 221
                 vywEe+le+++++lr+elgie+pp
  EEA19582.1 238 VYWEEQLERNVDDLRTELGIETPP 261
                 *********************987 PP

>> DUF2236  Uncharacterized protein conserved in bacteria (DUF2236)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.2   1.4e-05      0.12      97     175 ..     187     271 ..     181     284 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.4e-05
     DUF2236  97 vhatfsasflraygrt...vgpltaeeeeayyhewrrvgrllGvpdrll..patraafdayldemvlael..evdeearelgdarl 175
                  ++ f  ++l ++g+    v +l ++e+e+++ +   ++   G++ ++l     ++++++  d+  ++el  e++++ re++++++
  EEA19582.1 187 KAFEFLNTVLPMTGLSlaaVVRLKPAERERFFKLHLPWAVRSGLSSEELinVYWEEQLERNVDDL-RTELgiETPPDLREIRRMMR 271
                 5678888999888866445666*************************998744678999999999.89999999999999965554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (287 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       584  (0.0325729); expected 358.6 (0.02)
Passed bias filter:                      458  (0.0255452); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.40
# Mc/sec: 2174.55
//
Query:       EEA19583.1  [L=692]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   9.4e-103  344.3   5.1    6.3e-98  328.4   1.6    2.0  2  TrkH      Cation transport protein
  ------ inclusion threshold ------
       0.11   12.2   1.2        2.3    8.0   0.0    2.5  2  DUF4538   Domain of unknown function (DUF4538)


Domain annotation for each model (and alignments):
>> TrkH  Cation transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.1   1.5e-07    0.0013      59     115 ..      46     101 ..      15     131 .. 0.65
   2 !  328.4   1.6    7e-102   6.3e-98     116     499 ..     267     669 ..     263     672 .. 0.94

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 1.5e-07
        TrkH  59 aslafldalfeavsgltttglsvivveeslprsgltlraqlqqiGglgvvvlaylsl 115
                  s++++dalf avs++t+tgl++i   ++l+ + + ++ +l+ +G++  v++a + +
  EEA19583.1  46 RSVRYIDALFFAVSAMTETGLNTINL-STLNMFQQVILCFLSIVGSTIWVSIAIVLV 101
                 45666666666666666666666554.666666666666666666666666664444 PP

  == domain 2  score: 328.4 bits;  conditional E-value: 7e-102
        TrkH 116 ptlgrgsaflylseaqkeelggkelrslselikilvvyyvgleilafvllvvliytakaysevvdstgvsplwwaffhsmSafnnlGfsltpnSlasfn 214
                   +gr+s f  lsea++  lgg+e+r++ +l++i+ +y+++++ l++++    +y+a   +   +++ ++p w ++f ++Safnn G+sl+++  ++f+
  EEA19583.1 267 EMFGRNSSFHHLSEAERRRLGGVEYRAICLLSVIVPLYLFLWQFLGALAV--GAYMARNHGDLSRQNRLNPWWIGIFFAISAFNNSGMSLLDANVVPFQ 363
                 679*******************************************9987..9****999**99*********************************** PP

        TrkH 215 knivillvaiifiilGnigFpillrviiaikkkilrdl...kqikeslsflldlprrcftLllasgfvwllllelavlnvtdnilfilldegslvvksi 310
                 +  + l+ + ++i++Gn+ +pi+lr  + + kk ++      q+ e + fll++prrc t l++s  +w+ll  ++vln td++ f +l+ ++ +++si
  EEA19583.1 364 NSRFFLITVGLLILAGNTCYPIFLRWCLVVIKKFTPNTdyfTQYHETVTFLLQHPRRCYTTLFPSTYTWWLLCLVIVLNCTDWVAFEVLNYDNPAIDSI 462
                 *************************988888887776555599******************************************************** PP

        TrkH 311 pkgsrvlkalFqsvstrtaGFsvvdlsnlhpaikvllvlmmyigglpgStaggIrrtnvyeefslgky.eieqekepkav..................s 390
                 p gsr+l++lFq+++ r+ GF vv++++l+ + +vl+v+mmyi ++p  +++ +r+ nvyee+slg+y +  + +e ++                    
  EEA19583.1 463 PLGSRILDGLFQAICVRSGGFYVVSIASLQISLQVLYVVMMYIAVYP--VVITMRNSNVYEERSLGIYaDDPSANEGDHSqssssadsqnpllrwvprG 559
                 ***********************************************..*******************5322333333346899*************99 PP

        TrkH 391 kksidgkhlerqllvdlwslflvlliilileglklsdvqepdfsffdiLfevvSaygtvGLSlG.a.knaslsaqlttisklvlialmirGrlrglpvl 487
                 ++ ++  +l+ ql +dlw l l ++ii i+e    +      +s+f i+fe+vSayg vGLS+G + +  s+s   +t+sklvl+a+mirGr+rglpv+
  EEA19583.1 560 RAYFVEHQLRLQLAHDLWWLGLAVIIISIIEAGNFTRDP-LTYSVFNIIFETVSAYGCVGLSTGlPnEAYSFSGGWRTLSKLVLCAVMIRGRHRGLPVA 657
                 99*****************************98887655.47***********************999******************************* PP

        TrkH 488 ldraillpsdkl 499
                 +d aillps+ +
  EEA19583.1 658 IDKAILLPSEHM 669
                 *********975 PP

>> DUF4538  Domain of unknown function (DUF4538)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   0.0   0.00026       2.3       3      26 ..     364     387 ..     362     391 .. 0.90
   2 ?    2.3   0.3     0.016   1.4e+02      14      27 ..     500     513 ..     494     523 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00026
     DUF4538   3 glkyvllvggvvgliglalYPiii 26 
                 + +++l+ +g++ l g ++YPi++
  EEA19583.1 364 NSRFFLITVGLLILAGNTCYPIFL 387
                 67999*****************97 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.016
     DUF4538  14 vgliglalYPiiia 27 
                 v ++ +a+YP++i 
  EEA19583.1 500 VVMMYIAVYPVVIT 513
                 556789******96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (692 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       485  (0.0270511); expected 358.6 (0.02)
Passed bias filter:                      259  (0.0144459); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.75u 0.35s 00:00:01.10 Elapsed: 00:00:00.61
# Mc/sec: 3442.24
//
Query:       EEA19584.1  [L=817]
Description: N-ethylmaleimide reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.3e-96  323.8   0.0    1.8e-96  323.4   0.0    1.1  1  Oxidored_FMN  NADH:flavin oxidoreductase / NADH oxidase famil


Domain annotation for each model (and alignments):
>> Oxidored_FMN  NADH:flavin oxidoreductase / NADH oxidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  323.4   0.0  9.8e-101   1.8e-96       1     342 []     458     788 ..     458     788 .. 0.92

  Alignments for each domain:
  == domain 1  score: 323.4 bits;  conditional E-value: 9.8e-101
                   CCCS-EEETTEEESSSEEE----S-TTTTTCS.HHHHHHHHHHHHHHTT-SEEEEEEEESSCCC-SCTTSEE-SSGGGHHHHHHHHHHHHHTT-EEE CS
  Oxidored_FMN   1 kLFkPikignmtLknRivmapmtrlraldkgnvledlaaeyysqraeipvtliiteaafvnpksggfdnapgiwdeeqieewrklteavhengskvv 97 
                   +LFkP+kignm++++Ri+map+trlra+d+  +++ +++eyy qra  p tlii+e++fv++  ggf+napgiw eeq+ +wr++t++vh++g++++
    EEA19584.1 458 NLFKPLKIGNMQVQHRIAMAPLTRLRATDDR-IPTPMMKEYYGQRAAVPSTLIIAEGTFVSAACGGFSNAPGIWREEQLDAWRTITDEVHAKGCFMF 553
                   69***************************99.***************************************************************** PP

                   EEEE--GGGS..SCSTCEC..SS.ESSSSSTTT-.S...CS-EE--HHHHHHHHHHHHHHHHHHHHTT-SEEEEEE-CTSHHHHHH-TTT----STT CS
  Oxidored_FMN  98 vqlwhlGreakseyladqevdspsdpvaldaqeeesaeevykkeltkeeikqliqefveAAkraieAgfDgVeihganGYLlnqFlspksnkrtDey 194
                    ql+  Gr+a  e  ++++vd  ++p+a++ +   +a++   +e+t e+ik ++ +fv+AAk+a+ AgfDgVeihganG+Ll+qF++  snkr D y
    EEA19584.1 554 CQLFAMGRAADIEISKKEGVD-IMAPSAIPIDDG-AAVP---QEMTIEQIKSTVLDFVDAAKNAVRAGFDGVEIHGANGFLLDQFIQDVSNKRDDAY 645
                   **************9999944.455778877743.4555...5****************************************************** PP

                   SSSHHHHHHHHHHHHHHHHHHH-SSSEEEEEECE--STTS--HHHHHHHHHHHCHCCEEEEEEETT-SSSSSTTS-TTTTHHHCCTTHHHHHHCCCH CS
  Oxidored_FMN 195 gGslenRarFllevvdaVkeavgeervgyRlSpedvvekgldfaetaqkivllkelekrlkdgkklalvhaaeprkrgagsvrteqekntefvkevw 291
                   gG++enR r l ev++aV++a+g+ervg RlSp + ++ +  + +    i   +++++++   +kla++h++e +  ga  + t+    ++f +e+w
    EEA19584.1 646 GGNIENRSRLLNEVINAVVDAIGAERVGLRLSPWSTFQGM-RMEDP---IPQFSDIIDNAS-KSKLAYLHLIESQMSGAEDSATS--DSLNFAYELW 735
                   ***********************************99655.56677...888888888888.789********999999999999..999******* PP

                   SSEEEE-SS--SHHHHHHHHHT..TS-SEEEESTHHHH-TTHHHHHHCCTCGG CS
  Oxidored_FMN 292 kkplitvgriadeekaaeivae..geadLvamgRefladpdlveklkkglpln 342
                   ++pl+ +g+++ +e    + ++  ++  +v +gR+f+++pdlv+k+k+gl+ln
    EEA19584.1 736 NGPLLVAGGYTPNEARRLVDEQypEKDIVVIFGRYFISNPDLVFKVKEGLELN 788
                   **************666666666555667889******************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (817 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       508  (0.028334); expected 358.6 (0.02)
Passed bias filter:                      469  (0.0261587); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.83u 0.35s 00:00:01.18 Elapsed: 00:00:00.56
# Mc/sec: 4372.30
//
Query:       EEA19585.1  [L=429]
Description: hypothetical protein PMAA_003730 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.4e-23   81.8   0.0    1.3e-22   81.0   0.0    1.4  1  SET            SET domain
  ------ inclusion threshold ------
       0.16   12.0   0.9       0.35   10.9   0.9    1.5  1  SWIRM-assoc_1  SWIRM-associated region 1
       0.33   11.5   3.0       0.39   11.2   0.7    2.0  2  FlgN           FlgN protein


Domain annotation for each model (and alignments):
>> SET  SET domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.0   0.0   2.2e-26   1.3e-22       1     169 []      37     277 ..      37     277 .. 0.86

  Alignments for each domain:
  == domain 1  score: 81.0 bits;  conditional E-value: 2.2e-26
                 SCEEEESSXBXTTXEEEEEEECCEECHHHHHHHHHH............................................................... CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............................................................... RF
         SET   1 GrGvfAtedIpkgeficeypeeiiltkdeadksele............................................................... 36 
                 G G++At+dI+++e+++e+p++++l+ d     + +                                                               
  EEA19585.1  37 GLGMIATRDIQENEVMVEVPRSAMLSIDSIPADFVNmfngisthgllaaflthgdpktlkrydlwkatwptlpdfeegmpilwskelggsglktpisti 135
                 89*********************************9************************999999999999999999888888888888888666555 PP

                 ........HTEEEEEXGGXX.........GGSX...HHHHHHHTTSSHHHHHHHHHHHHHHHHHHTHHHHHHHXTTTSXXXHCCCCCHCCCHEEEETEE CS
                 ........xxxxxxxxxxxx.........xxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         SET  37 ........aylfslpeapkn.........laft...kelakasastllqklakdqkqaekedtdaalkasskaesdlnaskpeagafsaiagysidara 115
                                    +           ++   k   +++ +t+ q+l ++q+ ++ e++++ +++++++ + +          + + ++++++r+
  EEA19585.1 136 attshqhdL----------SpitlppsvsGLWNtfhKKPLAEEYTTKHQNLLAQQEARLREAWRDVIAVFPDTDWEK----------FSYHWLIVNTRS 214
                 555333320..........122333445533324669**********************************887766..........888999999999 PP

                 EEEECCC.............GTTGGGCEEXSSSSEEEEEEEETTSSEEEEEESSXBXTTEEEEEXTT CS
                 xxxxxxx.............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         SET 116 lksgnga.............gplarflNHsCdpNcnltvqnvlrgprvavfAtrdIkkGeEltidYg 169
                 +++  +              +p+a+++NH  d  c  +v +  +g+ ++++Atr +kkGeE++++Yg
  EEA19585.1 215 FYYLMPGqdppedtndamamVPFADYFNHTDDAEC--EVHF--DGKSYTFRATRLYKKGEEIYMSYG 277
                 988888899999999999*****************..6666..67*********************8 PP

>> SWIRM-assoc_1  SWIRM-associated region 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.9   5.8e-05      0.35      44      79 ..     388     423 ..     385     427 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 5.8e-05
  SWIRM-assoc_1  44 feelEklleaerrelekqrqqLlleRlalkkevlkv 79 
                    +++lE++l++e+++l +++ ++l+ R +  k++ ++
     EEA19585.1 388 MAKLEEMLSREKDSLAQRKIKMLIGRWEQIKQLCEA 423
                    689***********************9999987665 PP

>> FlgN  FlgN protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.1      0.24   1.4e+03      78      96 ..     174     191 ..     161     195 .. 0.70
   2 ?   11.2   0.7   6.5e-05      0.39      11      54 ..     381     424 ..     379     427 .. 0.91

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.24
                 HHHHCTTCCHHHHHHHHHH CS
        FlgN  78 sellakeedeelkelwqel 96 
                 ++lla +++++l+e+w+++
  EEA19585.1 174 QNLLA-QQEARLREAWRDV 191
                 44555.6999999999876 PP

  == domain 2  score: 11.2 bits;  conditional E-value: 6.5e-05
                 HHHHHHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHH CS
        FlgN  11 leeelelleeLlelleeEteaLkagdieaLeelleekqellekl 54 
                 l++  e++ +L+e+l +E++ L +++i+ L +  e++++l e++
  EEA19585.1 381 LKDATETMAKLEEMLSREKDSLAQRKIKMLIGRWEQIKQLCEAV 424
                 6777899*****************************99998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (429 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       525  (0.0292822); expected 358.6 (0.02)
Passed bias filter:                      458  (0.0255452); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.71u 0.31s 00:00:01.02 Elapsed: 00:00:00.55
# Mc/sec: 2353.52
//
Query:       EEA19586.1  [L=519]
Description: 2-dehydropantoate 2-reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-33  116.1   0.8    1.7e-33  115.5   0.8    1.3  1  ApbA_C           Ketopantoate reductase PanE/ApbA C terminal
    1.4e-28   99.5   0.0    9.1e-27   93.6   0.0    2.3  1  ApbA             Ketopantoate reductase PanE/ApbA
  ------ inclusion threshold ------
       0.12   11.7   0.0       0.22   10.8   0.0    1.3  1  ThiF             ThiF family
       0.15   12.0   0.2       0.67   10.0   0.1    2.1  2  V_ATPase_prox    Vacuolar ATPase Subunit I N-terminal proxima
       0.29   11.7   1.4        9.7    6.8   0.0    2.3  2  Tnp_P_element_C  87kDa Transposase


Domain annotation for each model (and alignments):
>> ApbA_C  Ketopantoate reductase PanE/ApbA C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.5   0.8   4.7e-37   1.7e-33       2     122 ..     360     489 ..     359     492 .. 0.95

  Alignments for each domain:
  == domain 1  score: 115.5 bits;  conditional E-value: 4.7e-37
      ApbA_C   2 irlarweKllinaainpltalldckngellespelralvrallkEalavaeaeg.........velseerleeaveavlektaanrsSMlqDveagrkt 91 
                 i+++++eKl++n++inpltalld+kngell + ++ + +r ll+E++ v+ a+           ++s+erl++ v +++++ta+n+sSMlqDv a + t
  EEA19586.1 360 ILQDQLEKLAMNCVINPLTALLDVKNGELLYNYHMTRSMRMLLAEISTVICALPeldgvpgvkERFSTERLKARVIKLANATAQNTSSMLQDVHAMKTT 458
                 789***********************************************7777788899985559999****************************** PP

      ApbA_C  92 EidyinGavvklAeklgvetPvnellyellk 122
                 Ei+yinG++v+++++lg+ +  n ++++l+ 
  EEA19586.1 459 EIEYINGYIVRRGNELGIRCALNYMIMQLVL 489
                 *****************************95 PP

>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.6   0.0   2.5e-30   9.1e-27       1     149 [.     116     315 ..     116     318 .. 0.90

  Alignments for each domain:
  == domain 1  score: 93.6 bits;  conditional E-value: 2.5e-30
                 EEEES-SHHHHHHHHHHHH.HTHC.EEEE-SCH.HHHHHHHHCEEEEETT...CEEEEEECEEECCH................................ CS
        ApbA   1 iailGaGaiGsllaakLak.agad.vtlilrsr.rlealkknGlrltseg...geeilrppealsae................................ 61 
                 i+ilG+G iG+++a++La    ++ +tl+l++r  +e++ ++  +++  +    +++  +++++ +                                 
  EEA19586.1 116 IHILGMGNIGCFVAHSLASrMTRPlITLLLHNRdMYERWLQRKQTIRLMTngsDDNKTGFDVNVLDNktwysmpywdernprlspeeeeenytsqletn 214
                 8****************98555559*************88887777776665744444444444444567779************************** PP

                 ........SCCCCS-ESEEEE-SSGGGHHHHHHHHGGGECTCEEEEEESSSSCHHHHHTTTS.....TTSEEEEEEEE-EEEEEETTEEEECS--EEEE CS
        ApbA  62 ........ekselepidlvivtvKayqteealeeikplldpntvvlllqNGlgheeelreal.....pkprvlggvtthgatregpgevhhagkgeiki 147
                         +  ++e+i+ +ivt+Ka  t++al+++ ++l+p+++vl+lqNG+g+ +e+ e++     ++p+ l+g+++hg++ ++p++++ +g g++ i
  EEA19586.1 215 dapssevdDFTDDEKIECLIVTTKAPLTVKALSSVSHRLTPDSTVLFLQNGMGVIDEVNEKVfpdpsDRPHYLQGIISHGVKMKKPFHIEYTGLGTTSI 313
                 ********99*******************************************************98889***************************** PP

                 EE CS
        ApbA 148 ge 149
                 g+
  EEA19586.1 314 GN 315
                 97 PP

>> ThiF  ThiF family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   6.2e-05      0.22      18      39 ..     113     134 ..     102     143 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 6.2e-05
                 TSEEEEE--SHHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxx RF
        ThiF  18 dskvllvGaGglGsellknLal 39 
                 + +++++G+G +G+++++ La 
  EEA19586.1 113 SGRIHILGMGNIGCFVAHSLAS 134
                 579*****************95 PP

>> V_ATPase_prox  Vacuolar ATPase Subunit I N-terminal proximal lobe
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       2.1   7.7e+03      11      23 ..     396     408 ..     395     410 .. 0.78
   2 ?   10.0   0.1   0.00019      0.67      12      36 ..     489     513 ..     487     515 .. 0.91

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 2.1
  V_ATPase_prox  11 rLareLLaeLqrv 23 
                    r  r LLae+  v
     EEA19586.1 396 RSMRMLLAEISTV 408
                    55799****8765 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00019
  V_ATPase_prox  12 LareLLaeLqrvGvvhLdPLeveeL 36 
                    L r+ ++ L+  G v L PLevee+
     EEA19586.1 489 LGRNQISKLREAGAVPLSPLEVEEM 513
                    67888999****************7 PP

>> Tnp_P_element_C  87kDa Transposase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   1.2     0.058   2.1e+02       8      77 ..     151     227 ..     146     231 .. 0.60
   2 ?    6.8   0.0    0.0027       9.7      71      91 ..     452     472 ..     405     476 .. 0.74

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.058
  Tnp_P_element_C   8 tdewlnld.tskelenetsesn........esfisasiftkAeiePelkadeeeedlsdeeelssnsdsaieldeqeeD 77 
                       + wl  + t+  ++n +++++        ++    s+    e +P l  +eeee++  +++l +n   ++e+d+ + D
       EEA19586.1 151 YERWLQRKqTIRLMTNGSDDNKtgfdvnvlDNKTWYSMPYWDERNPRLSPEEEEENY--TSQLETNDAPSSEVDDFTDD 227
                      577887553555444444444466666555555555555666779999888888884..45555555555788877666 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.0027
  Tnp_P_element_C  71 ldeqeeDgleYivGyvirklr 91 
                      +  ++   +eYi Gy+ r+ +
       EEA19586.1 452 VHAMKTTEIEYINGYIVRRGN 472
                      333667779*********966 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (519 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       523  (0.0291706); expected 358.6 (0.02)
Passed bias filter:                      496  (0.0276647); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.63u 0.31s 00:00:00.94 Elapsed: 00:00:00.51
# Mc/sec: 3076.08
//
Query:       EEA19587.1  [L=288]
Description: exosome-associated family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.1e-17   63.0   1.5    3.1e-17   63.0   1.5    2.9  3  Sas10_Utp3   Sas10/Utp3/C1D family
  ------ inclusion threshold ------
        0.2   11.0  36.5       0.29   10.5  36.5    1.2  1  Nop53        Nop53 (60S ribosomal biogenesis)
        1.5    7.8  20.3        1.7    7.6  20.3    1.2  1  LAP1C        Lamina-associated polypeptide 1C (LAP1C)
          5    7.2   6.4        1.3    9.1   0.4    2.6  2  DUF5619      Domain of unknown function (DUF5619)


Domain annotation for each model (and alignments):
>> Sas10_Utp3  Sas10/Utp3/C1D family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.0   1.5   6.8e-21   3.1e-17       2      87 .]      11      88 ..      10      88 .. 0.90
   2 ?   -1.3   2.2      0.79   3.5e+03      16      26 ..     163     173 ..     134     200 .. 0.53
   3 ?   -1.6   0.3         1   4.5e+03      28      42 ..     225     236 ..     207     253 .. 0.48

  Alignments for each domain:
  == domain 1  score: 63.0 bits;  conditional E-value: 6.8e-21
  Sas10_Utp3  2 eslsksldelqeslepllskakaeekkslsdeklsegisllslKnelllaYllnlllylllklsgvelkdhpvvkeLvrlRvyleK 87
                + l++++d+l+e+leplls++ +e++     +kl+    l+++K+++ll+Y+l++l++++l l+g+++++hpv+keL+r+++y+ K
  EEA19587.1 11 DRLEDNIDDLEEALEPLLSRSLDETS-----KKLPL---LERAKLHALLTYILESLIFSYLTLHGTNAQEHPVFKELTRVKQYYAK 88
                57999**************7544442.....46888...********************************************977 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.79
  Sas10_Utp3  16 epllskakaee 26 
                 ++l++ ++++e
  EEA19587.1 163 QELSKPSTEAE 173
                 33333222222 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 1
  Sas10_Utp3  28 kslsdeklsegisll 42 
                 k+++++ +++   l 
  EEA19587.1 225 KAKAKQRKEN---LI 236
                 1111122222...33 PP

>> Nop53  Nop53 (60S ribosomal biogenesis)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5  36.5   6.5e-05      0.29     204     354 ..     125     285 ..     115     288 .] 0.51

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 6.5e-05
       Nop53 204 aveaEkk.rekeeeklerkrekiaekaataeareeelseekde......gleeeeeeeeeeeeeeeeeeeesee.............eeklnapvkkkp 282
                  +++E++ r+++e++ ++ ++++ +k+ ++e   ++ s+e ++      + e+e+ee+e+e+++++                          ++ +++p
  EEA19587.1 125 QYDIERAeRQAKEKARAQLKAAMLAKKSKEESSASTPSQELSKpsteaeSSESESEESEDESPSDS-------IdtkpaksvspigdF----IKLSSEP 212
                 577777624444444444455555555555555555555555455543222222222222222222.......133344456655432....3345667 PP

       Nop53 283 krKTkaqRnkekrrkeeekeekeekkekkkeaqlerlkeikkevaekekeraeaae.arkkekrkkkaekkkl 354
                     k  ++k +++k+++++e+  k+++++ ++  ++k i +  ++++++  ++++ +rk++krk+k+++kk 
  EEA19587.1 213 MAESKNAKKKTAKAKAKQRKENLIKAKRAEPQATREAKGIPEPDNKQQRTMSRKERrRRKEAKRKEKNNDKKK 285
                 7777888888888888888888888888888888888888665555555554442202333333333333332 PP

>> LAP1C  Lamina-associated polypeptide 1C (LAP1C)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6  20.3   0.00039       1.7      43     199 ..     127     282 ..      52     288 .] 0.56

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.00039
                 ............XXXXXXXXXXXXXX..XXXXXXXXXXXX...........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXX CS
       LAP1C  43 etigsesadtedkseseqevnlseepkdetEeedsessqsge.eghklsseslgeekldsedsvsssdktgradaqleessaalseeasdrtaasqeps 140
                 +++   + ++++k++ + ++++  ++++e+ + ++ s++ ++ + +  sses +ee+ d+++s s + k +++ + + + +  +se  ++ ++a+++  
  EEA19587.1 127 DIERA-ERQAKEKARAQLKAAMLAKKSKEESSASTPSQELSKpSTEAESSESESEESEDESPSDSIDTKPAKSVSPIGDFIKLSSEPMAESKNAKKKTA 224
                 22222.222233333333333333222222223333333333033444566777777777777777777778888877777777777777777777776 PP

                 X......XXXXXXXXXXXXXXXXXXXXX..XXXX..XXXXXXXXXXXX.XXXXXXXXXXX CS
       LAP1C 141 aadsqeaqssghskaeqeeqdtlrrtrllvpeaeshqqetelleeske.saqdtlrkskk 199
                 +a++++ +++  +++  e q+t+    +  pe +++qq+t  ++e++  +  +  +k+++
  EEA19587.1 225 KAKAKQRKENLIKAKRAEPQATREAKGI--PEPDNKQQRTMSRKERRRrKEAKRKEKNND 282
                 6666666666666666666666666444..444444665555555443222222222222 PP

>> DUF5619  Domain of unknown function (DUF5619)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.4   0.00029       1.3      11      54 ..     124     167 ..     104     175 .. 0.85
   2 ?    0.5   0.5      0.14   6.2e+02       4      32 ..     206     234 ..     204     239 .. 0.75

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00029
                 S---HHHHHHHH---TT---E.EEEEEEEE-----EES---SSS CS
     DUF5619  11 sdldfekAkklAkeiAeelleepmllsWkdrkrgkesPevecge 54 
                  + d e+A++ Ake+A+ +l+ +ml   + ++++ ++P  e ++
  EEA19587.1 124 DQYDIERAERQAKEKARAQLKAAMLAKKSKEESSASTPSQELSK 167
                 56799************999999998888888888888866554 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.14
                 E----S.S---HHHHHHHH---TT---E. CS
     DUF5619   4 iklniegsdldfekAkklAkeiAeellee 32 
                 ikl++e+++ + ++ kk+Ak++A++  e+
  EEA19587.1 206 IKLSSEPMAESKNAKKKTAKAKAKQRKEN 234
                 67788877777777789999999976554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (288 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2499  (0.139383); expected 358.6 (0.02)
Passed bias filter:                      552  (0.0307881); expected 358.6 (0.02)
Passed Vit filter:                       132  (0.00736237); expected 17.9 (0.001)
Passed Fwd filter:                        47  (0.00262145); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.94u 0.37s 00:00:01.31 Elapsed: 00:00:00.53
# Mc/sec: 1648.18
//
Query:       EEA19588.1  [L=165]
Description: CHCH domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.9e-08   33.1  10.5    7.4e-08   32.8  10.5    1.0  1  DUF2076   Uncharacterized protein conserved in bacteria (DUF2
    2.7e-05   24.2   2.2    4.1e-05   23.6   2.2    1.3  1  CHCH      CHCH domain
  ------ inclusion threshold ------
      0.019   14.9   0.5      0.031   14.3   0.5    1.3  1  CX9C      CHCH-CHCH-like Cx9C, IMS import disulfide relay-sys


Domain annotation for each model (and alignments):
>> DUF2076  Uncharacterized protein conserved in bacteria (DUF2076)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.8  10.5   1.2e-11   7.4e-08     103     230 ..      10     140 ..       2     147 .. 0.56

  Alignments for each domain:
  == domain 1  score: 32.8 bits;  conditional E-value: 1.2e-11
     DUF2076 103 pqpspqarpaapagqalgqeeq..yaaqpgyaqqqaqpqygqpaaapqpggGggFLggAlqtAAGVaGGvllangleslfsgksgeegaasa..sqsae 197
                 p+++++++p++p + +++ + +  +++qp++   +++p+++q++++p +++G g +g  ++tAAGVa G+ ++ ++ s f g+s++  +++a  +qs++
  EEA19588.1  10 PAAPARSAPSRPIAAPARPAAPqqHQSQPHSTA-AYPPAAQQAPPMPVQSQGPGLFGQMASTAAGVAVGSSIGHAVGSWFTGGSSAPVEQAAppAQSQA 107
                 333444444444433333222200223332222.3344433333333369999*****************************88766666667855555 PP

     DUF2076 198 eeeiinnyyssssladdaedadnasadsfadsd 230
                  +  +  + +s+s++++ + a++a++ ++  +d
  EEA19588.1 108 MDSGLYATNTSQSAWENPACATDAQNFRKCMDD 140
                 555444433455555555555555555444444 PP

>> CHCH  CHCH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.6   2.2   6.9e-09   4.1e-05       1      34 [.     127     160 ..     127     161 .. 0.96

  Alignments for each domain:
  == domain 1  score: 23.6 bits;  conditional E-value: 6.9e-09
                 THHHHHHHHHHHHHCTSSTTTTHHHHHHHHHHHC CS
        CHCH   1 CgeefkeylkClkdnsdefskCrkefeafkeCvk 34 
                 C+   +++ kC++dn  +   C+++++++k+C+ 
  EEA19588.1 127 CATDAQNFRKCMDDNKGDLTICGWYLDQLKACQA 160
                 9999****************************85 PP

>> CX9C  CHCH-CHCH-like Cx9C, IMS import disulfide relay-system,
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.5   5.2e-06     0.031       8      40 ..     127     159 ..     125     162 .. 0.92

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 5.2e-06
        CX9C   8 CpkefeaYhkCvssnqswpekCkeqkkeLakCi 40 
                 C  +  ++ kC+ +n+ + + C  + ++L  C 
  EEA19588.1 127 CATDAQNFRKCMDDNKGDLTICGWYLDQLKACQ 159
                 888999**************************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (165 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       703  (0.0392102); expected 358.6 (0.02)
Passed bias filter:                      410  (0.022868); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.44u 0.29s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 1115.27
//
Query:       EEA19589.1  [L=476]
Description: UBX domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.2e-11   43.8   0.0    4.5e-11   42.8   0.0    1.6  1  UBX            UBX domain
  ------ inclusion threshold ------
       0.15   12.4  12.4       0.33   11.3  12.4    1.5  1  Vfa1           AAA-ATPase Vps4-associated protein 1
       0.91    9.5  22.4       0.02   14.9  16.0    1.5  2  TFIIA          Transcription factor IIA, alpha/beta subunit
        4.4    7.1  12.0        7.7    6.3  12.0    1.5  1  RR_TM4-6       Ryanodine Receptor TM 4-6
        8.7    5.4  10.2         14    4.7  10.2    1.3  1  Tho2           Transcription factor/nuclear export subunit pr


Domain annotation for each model (and alignments):
>> UBX  UBX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.8   0.0   1.3e-14   4.5e-11       2      80 ..     274     357 ..     273     358 .. 0.91

  Alignments for each domain:
  == domain 1  score: 42.8 bits;  conditional E-value: 1.3e-14
                 TTSSEEEEEEEETTSTEEEEEEESSSBHH.HHHHHHHHHCCCCCTSEEE...EETTTTEEGGCCC.CSBCCCCTTTSCEEEEEE CS
         UBX   2 eaedatrlqiRlpdGsrlvrrFkksdtle.svyeyVdsklfekeepFqL...ltsfPrreltksd.kktLsdlgllpnstlvle 80 
                 ++ ++ rlqiRl dG + ++ F++s+t++ +v+ + + ++ + +ep+ L   lt++P+r+++ ++ ++tL++l+l p ++lv+ 
  EEA19589.1 274 KQPTEYRLQIRLFDGRSVRNSFPPSATIRkDVRPWLENQRSDGAEPYNLkhiLTPLPNRTISVAEeERTLEELELGPTASLVMV 357
                 567789******************9999637***************998555799***************************95 PP

>> Vfa1  AAA-ATPase Vps4-associated protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3  12.4   9.1e-05      0.33      59     156 ..     204     292 ..     177     313 .. 0.48

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 9.1e-05
        Vfa1  59 eeaakkkke..leeeiekvkkeyeekqkkkkekekkkkekdkkdkdkkkekekdkkkekekeeekkkelkkaeeeleekeeprvkkykLhkefyqsRle 155
                 e+  ++kk+   e+e + ++++++++qk++ke++++     +++   kk++e+ +++ +e e++ +++++++ ++   +++++ ++y L+ ++++ R  
  EEA19589.1 204 ET-PEQKKAlqEEKERRALQSKIQREQKEQKEERERI----RNQ--IKKDQEARRQRADE-EKNISNATSSSRTS---RTNKQPTEYRLQIRLFDGRSV 291
                 22.1222221133333344444444444444333322....111..11111111111111.12222222222222...34555667********99976 PP

        Vfa1 156 r 156
                 r
  EEA19589.1 292 R 292
                 5 PP

>> TFIIA  Transcription factor IIA, alpha/beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9  16.0   5.4e-06      0.02     112     304 ..      68     262 ..      29     317 .. 0.45
   2 ?   -3.4   0.4         2     7e+03     112     112 ..     428     428 ..     406     464 .. 0.36

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 5.4e-06
       TFIIA 112 taatfslpakleppvqipagvtlqtasg.qlykvnvqasgaqqiaaqplqqvvqqsqgsaaqssvaalqaqsqqaqalaepqqqlekq.......qqqq 202
                 +  t   p+++ p v ++ + +lq      + k   q++ +++iaa+ ++     +++ +a+s++++ ++++   q++ ep q  ++        q+  
  EEA19589.1  68 GFLTSICPIQTFPAVIVIRNGMLQEYLVaGTAKDAFQTRLKTAIAANTAAVE---TTPLVASSDTTHTTESQAPPQTIREPVQPRAPVapttpqpQA-- 161
                 4455555555555555554333333332132333335555555554444444...233333333333333322223333333332211222221111.. PP

       TFIIA 203 qqqqqqqqqqqvqqqqqe.......esqqaqqasqe.......qvag.sqvessqtdgaedaleeespv..legelsaeeeagaqkeelsreeidrire 284
                           q+qq+ ++       + +q++++  +       ++   +++e  +t ++++al+ee++   l+ ++++e++++++++e  r++i++   
  EEA19589.1 162 ----------QTQQEPMRippvsqfPTSQPTHT--TtgasdreNIRAgKRPETYETPEQKKALQEEKERraLQSKIQREQKEQKEERERIRNQIKKD-- 246
                 ..........22222222333323322222222..01122334333336666666666666666655554445555444444444333333333322.. PP

       TFIIA 285 ealkakelekeskkkkraee 304
                 ++ +++  ++e++     ++
  EEA19589.1 247 QEARRQRADEEKN----ISN 262
                 1111111111111....111 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 2
       TFIIA 112 t 112
                 t
  EEA19589.1 428 T 428
                 0 PP

>> RR_TM4-6  Ryanodine Receptor TM 4-6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3  12.0    0.0021       7.7      64     155 ..     182     271 ..     112     291 .. 0.55

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0021
                 XXXXXXXXXXXXXXXXXXXX....XXXXXXXXXXXXXXXXXXXXXXXXXXX.XXX.XXXXXXXXXXXXX..........XXXXXXXXXXXXXXXXXX CS
    RR_TM4-6  64 kkseagLgDlseteaeespt....pelkkklaeeeeaeeekeeeeepeaeaeeka.daengekeekekekeeeekeseeeeeekkkkkkakskkkee 155
                 ++++ g +D  +  a + p+    pe+kk l+ee+e    +++ + +++e++e++   +n+ k+       ++e +++  +eek+  ++++s++   
  EEA19589.1 182 THTTTGASDRENIRAGKRPEtyetPEQKKALQEEKERRALQSKIQREQKEQKEEReRIRNQIKK-------DQEARRQRADEEKNISNATSSSRTSR 271
                 3444444555554444444433333333333332222222222222222221111011112111.......12222222222222222222222222 PP

>> Tho2  Transcription factor/nuclear export subunit protein 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7  10.2     0.004        14      45      96 ..     201     252 ..     178     270 .. 0.75

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.004
        Tho2  45 rsderaaakkkkkekkrlkeliekLeeEkkeqiehvekvkkrLkeekkswfk 96 
                 ++ e+ ++kk  +e+k+ ++l++k+++E+keq+e++e++++++k+ ++   +
  EEA19589.1 201 ETYETPEQKKALQEEKERRALQSKIQREQKEQKEERERIRNQIKKDQEARRQ 252
                 333366777788888888999***********************98876554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (476 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2799  (0.156116); expected 358.6 (0.02)
Passed bias filter:                      934  (0.0520944); expected 358.6 (0.02)
Passed Vit filter:                       164  (0.00914719); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.89u 0.33s 00:00:01.22 Elapsed: 00:00:00.49
# Mc/sec: 2939.98
//
Query:       EEA19590.1  [L=388]
Description: UBX domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.6e-11   44.3   0.0    3.2e-11   43.3   0.0    1.6  1  UBX            UBX domain
  ------ inclusion threshold ------
       0.07   13.5  11.9       0.15   12.3  11.9    1.5  1  Vfa1           AAA-ATPase Vps4-associated protein 1
        6.3    5.6   7.9        9.1    5.1   7.9    1.2  1  PA26           PA26 p53-induced protein (sestrin)
        7.1    5.7  10.2         11    5.2  10.2    1.2  1  Tho2           Transcription factor/nuclear export subunit pr
        8.1    5.2   4.6         10    4.9   4.6    1.1  1  LMBR1          LMBR1-like membrane protein


Domain annotation for each model (and alignments):
>> UBX  UBX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.3   0.0     9e-15   3.2e-11       2      80 ..     186     269 ..     185     270 .. 0.91

  Alignments for each domain:
  == domain 1  score: 43.3 bits;  conditional E-value: 9e-15
                 TTSSEEEEEEEETTSTEEEEEEESSSBHH.HHHHHHHHHCCCCCTSEEE...EETTTTEEGGCCC.CSBCCCCTTTSCEEEEEE CS
         UBX   2 eaedatrlqiRlpdGsrlvrrFkksdtle.svyeyVdsklfekeepFqL...ltsfPrreltksd.kktLsdlgllpnstlvle 80 
                 ++ ++ rlqiRl dG + ++ F++s+t++ +v+ + + ++ + +ep+ L   lt++P+r+++ ++ ++tL++l+l p ++lv+ 
  EEA19590.1 186 KQPTEYRLQIRLFDGRSVRNSFPPSATIRkDVRPWLENQRSDGAEPYNLkhiLTPLPNRTISVAEeERTLEELELGPTASLVMV 269
                 567789******************9999637***************998555799***************************95 PP

>> Vfa1  AAA-ATPase Vps4-associated protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3  11.9   4.3e-05      0.15      59     156 ..     116     204 ..      88     225 .. 0.48

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 4.3e-05
        Vfa1  59 eeaakkkke..leeeiekvkkeyeekqkkkkekekkkkekdkkdkdkkkekekdkkkekekeeekkkelkkaeeeleekeeprvkkykLhkefyqsRle 155
                 e+  ++kk+   e+e + ++++++++qk++ke++++     ++  + kk++e+ +++ +e e++ +++++++ ++   +++++ ++y L+ ++++ R  
  EEA19590.1 116 ET-PEQKKAlqEEKERRALQSKIQREQKEQKEERERI----RN--QIKKDQEARRQRADE-EKNISNATSSSRTS---RTNKQPTEYRLQIRLFDGRSV 203
                 22.1122221133333334444444444444333322....11..111111111111111.12222222222222...34556667********99976 PP

        Vfa1 156 r 156
                 r
  EEA19590.1 204 R 204
                 5 PP

>> PA26  PA26 p53-induced protein (sestrin)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   7.9    0.0025       9.1     183     271 ..      93     186 ..      63     199 .. 0.64

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0025
        PA26 183 sskklksasasanekedsseeeeeelerkaaaeaeaevealmermkklqeeedeee.....easeeelserfekeeseslllaaadaeeaavas 271
                  +++++ as ++n ++ +  e+ e+ e+k+a ++e+e +al++++++ q+e++ee+     ++++++ ++r   +e+++++ a+++++++ +++
  EEA19590.1  93 PTHTTTGASDRENIRAGKRPETYETPEQKKALQEEKERRALQSKIQREQKEQKEERerirnQIKKDQEARRQRADEEKNISNATSSSRTSRTNK 186
                 44455555555667777888888899999999999999*****999999998887644444222222222223333333333333333333333 PP

>> Tho2  Transcription factor/nuclear export subunit protein 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2  10.2    0.0029        11      45      96 ..     113     164 ..      90     182 .. 0.75

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.0029
        Tho2  45 rsderaaakkkkkekkrlkeliekLeeEkkeqiehvekvkkrLkeekkswfk 96 
                 ++ e+ ++kk  +e+k+ ++l++k+++E+keq+e++e++++++k+ ++   +
  EEA19590.1 113 ETYETPEQKKALQEEKERRALQSKIQREQKEQKEERERIRNQIKKDQEARRQ 164
                 333366777888888888999***********************98876554 PP

>> LMBR1  LMBR1-like membrane protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   4.6    0.0028        10     264     332 ..     102     181 ..      18     198 .. 0.64

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.0028
       LMBR1 264 s.............nenkteeslakle..kqlikalqkrertekqwkrllekalelediiknksskekefksses.srrgefakq 332
                               + ++++++l++++  ++l++++q++++++k+ ++ + ++     i k+++ ++++  ++++ s+ ++  ++
  EEA19590.1 102 DreniragkrpetyETPEQKKALQEEKerRALQSKIQREQKEQKEERERIRNQ-----IKKDQEARRQRADEEKNiSNATSSSRT 181
                 15555556566554333344555544433788899999999999999999998.....555555555555544444322222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (388 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2936  (0.163757); expected 358.6 (0.02)
Passed bias filter:                      963  (0.0537119); expected 358.6 (0.02)
Passed Vit filter:                       177  (0.00987227); expected 17.9 (0.001)
Passed Fwd filter:                        21  (0.00117129); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.87u 0.33s 00:00:01.20 Elapsed: 00:00:00.49
# Mc/sec: 2399.80
//
Query:       EEA19591.1  [L=340]
Description: COX1 assembly protein Shy1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.2e-46  156.6   0.0    1.3e-45  155.8   0.0    1.3  1  SURF1     SURF1 family


Domain annotation for each model (and alignments):
>> SURF1  SURF1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  155.8   0.0   7.1e-50   1.3e-45       2     176 .]      98     313 ..      97     313 .. 0.83

  Alignments for each domain:
  == domain 1  score: 155.8 bits;  conditional E-value: 7.1e-50
       SURF1   2 vpvvvlfgLGtWQlqRlkwkealiaeleerlaaeplplleka.lealeefeyrrvtvtGrfdhdkevlvgngqprv.....Gylvltplrl.edd.... 89 
                 +p +++f+LGtWQ+qRl+wk++lia+ e+rl ++plpl++++ +e+++ef+yrr+ +tG+++hd+e+l+g   pr+     Gy v+tpl++ +dd    
  EEA19591.1  98 IP-ITAFVLGTWQVQRLDWKTKLIAKFEDRLVKPPLPLPPRIdPEVIPEFDYRRIVATGEYRHDQEMLIG---PRMyegeeGYIVITPLQRtTDDdkng 192
                 67.899********************************9999555557**********************...99888999**********63337899 PP

       SURF1  90 .geavlVnrGWvpaea..eklpka.....apegeevrevtGllr....kss.tpapeeesgewqvqsidvaalaealgaqkvlpvvl............ 163
                  +++vl+nrGW++++   +    +      p+ ++v  v+Gl+r    k+  tp++ +++ge+  ++ d++++ae +g   ++p+++            
  EEA19591.1 193 nENTVLINRGWISKKLkdQ----KvrpegLPQ-GQVV-VEGLIRdpvkKNYfTPDNRPDKGEF--YFPDIEQMAELTG---SQPILIeetmvpdlietl 280
                 9************976432....123454333.4466.******8875555666444577866..***********98...777776666667777888 PP

       SURF1 164 ....................hlgYaltWfglaa 176
                                     hl+Y++tW+gl++
  EEA19591.1 281 nrtangvpigrpaqvnlrnnHLQYIFTWYGLSV 313
                 88889999999999999999***********96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (340 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       380  (0.0211947); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.47
# Mc/sec: 2188.13
//
Query:       EEA19592.1  [L=465]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-45  154.1   0.0    1.8e-45  153.5   0.0    1.3  1  CENP-T_C       Centromere kinetochore component CENP-T histon
    2.5e-08   34.2   0.1    4.5e-08   33.4   0.1    1.4  1  CENP-S         CENP-S protein
     0.0001   22.6   0.7    0.00028   21.2   0.1    2.0  2  Histone        Core histone H2A/H2B/H3/H4
  ------ inclusion threshold ------
      0.052   13.8   0.0        0.1   12.9   0.0    1.5  1  CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) a
       0.21   11.7   0.0       0.35   11.0   0.0    1.3  1  DUF531         Protein of unknown function (DUF531)
       0.36   10.8   2.3        5.1    7.1   0.0    3.1  3  Homeobox_KN    Homeobox KN domain


Domain annotation for each model (and alignments):
>> CENP-T_C  Centromere kinetochore component CENP-T histone fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  153.5   0.0     6e-49   1.8e-45       1     105 [.     357     462 ..     357     465 .] 0.97

  Alignments for each domain:
  == domain 1  score: 153.5 bits;  conditional E-value: 6e-49
    CENP-T_C   1 rgievpslPaavvkklakrfakasg.skaklekealkalekasdkffeqvgeDLeayakHagRKtidesDvilLmkrqrkvtskttlfslaqryLPrEl 98 
                 +gi vp lP++vvk++a+rfa++ + skak++ke+l+a+e+as++ffeq +eDL++y++HagRKtidesDv++Lm+rqr+v+  +t+fslaq++LP+El
  EEA19592.1 357 HGIPVPLLPTGVVKRIATRFARTGAgSKAKINKETLAAIEQASEWFFEQASEDLATYSRHAGRKTIDESDVVALMRRQRHVNRMNTVFSLAQKHLPKEL 455
                 7899*******************999************************************************************************* PP

    CENP-T_C  99 lqelrme 105
                 lq++r  
  EEA19592.1 456 LQDIRLG 462
                 ***9975 PP

>> CENP-S  CENP-S protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.4   0.1   1.5e-11   4.5e-08      21      74 ..     382     435 ..     368     437 .. 0.80

  Alignments for each domain:
  == domain 1  score: 33.4 bits;  conditional E-value: 1.5e-11
      CENP-S  21 ekeveatkqfiaaltelvykqlenlakDLeaFakHAkRstittdDvlLlaRrne 74 
                  ++ +++k+++aa+        e+ ++DL ++++HA+R+ti+ +Dv+ l+Rr++
  EEA19592.1 382 GSKAKINKETLAAIEQASEWFFEQASEDLATYSRHAGRKTIDESDVVALMRRQR 435
                 55667777777777777777778899**************************86 PP

>> Histone  Core histone H2A/H2B/H3/H4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.1       1.3   3.9e+03      28      62 ..      60      94 ..      28      97 .. 0.56
   2 !   21.2   0.1   9.5e-08   0.00028      52     130 ..     346     433 ..     340     434 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 1.3
                TS-SSSSB--TTT-XTTHHHHHHHHHHHHXXSXXS CS
     Histone 28 kasskskkkkkrryrpgtvalkeirkyqkstdlli 62
                +    +++++++   pg   ++  r  q++t+++i
  EEA19592.1 60 TPFGLRAMQRRTANTPGRDRRRSTRGPQQETAFDI 94
                34444555566666666666666666676666665 PP

  == domain 2  score: 21.2 bits;  conditional E-value: 9.5e-08
                 HHHHHXXSXXSXHHHHHHHHHHHH..........TTSSSXEEXHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTXSEEXHHHHHHHHHH CS
     Histone  52 rkyqkstdlliqklpfaRvvreivk.........sekedlrisaeavlalqealEallvelfeeAnllakhaKRvTitpkDiqlArrl 130
                 ++ qk+++l  + +p+  + + +vk           +++ +i +e++ a+ +a+E ++++  e+ + +++ha R+Ti   D+ + +r 
  EEA19592.1 346 KRTQKQKKLSRHGIPVPLLPTGVVKriatrfartGAGSKAKINKETLAAIEQASEWFFEQASEDLATYSRHAGRKTIDESDVVALMRR 433
                 5677777777777777765555555555599988899999******************************************998885 PP

>> CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) and archaeal histone
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   3.5e-05       0.1      17      61 ..     383     427 ..     363     431 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 3.5e-05
                    TXS-B-HHHHHHHHHHHHHHHHHHHHHHHHHHCCTTSSCE-HHHH CS
  CBFD_NFYB_HMF  17 darkiakdAkeliaecveefieelaseAaeickkekrKtikaehi 61 
                    + +ki+k+    i ++ e f e+ ++  a +  +++rKti + ++
     EEA19592.1 383 SKAKINKETLAAIEQASEWFFEQASEDLATYSRHAGRKTIDESDV 427
                    5789**************************************998 PP

>> DUF531  Protein of unknown function (DUF531)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00012      0.35      63     140 ..     378     458 ..     353     463 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00012
      DUF531  63 esGkylkelaeknrllvldlpkkgfpaqfGevvattskpdekkaitpeevaeeilrkksv...llliGlGrkGlPkellkl 140
                  +G+  k+ ++k+ l  ++  +  f  q  e +at s+   +k+i++++v+  + r++ v     ++ l +k lPkell+ 
  EEA19592.1 378 RTGAGSKAKINKETLAAIEQASEWFFEQASEDLATYSRHAGRKTIDESDVVALMRRQRHVnrmNTVFSLAQKHLPKELLQD 458
                 455555666788888999999999999*************************99999875222689***********9975 PP

>> Homeobox_KN  Homeobox KN domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0      0.44   1.3e+03       5      18 ..     275     288 ..     273     292 .. 0.80
   2 ?    1.4   0.1     0.099     3e+02       5      15 ..     293     303 ..     290     306 .. 0.81
   3 ?    7.1   0.0    0.0017       5.1      15      34 ..     383     402 ..     380     405 .. 0.90

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.44
  Homeobox_KN   5 hlhnPYPseedKee 18 
                   l++P P++ed  +
   EEA19592.1 275 DLDDPLPNDEDNFM 288
                  699*******9655 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.099
  Homeobox_KN   5 hlhnPYPseed 15 
                  h + PYPs +d
   EEA19592.1 293 HGEIPYPSSDD 303
                  6778****987 PP

  == domain 3  score: 7.1 bits;  conditional E-value: 0.0017
  Homeobox_KN  15 dKeeLlkeTglsvkqitnWF 34 
                   K+++ keT++ ++q + WF
   EEA19592.1 383 SKAKINKETLAAIEQASEWF 402
                  6999**************** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (465 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       461  (0.0257125); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 3277.79
//
Query:       EEA19593.1  [L=281]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.7e-74  248.0   9.9    1.1e-73  247.7   9.9    1.1  1  CMS1            U3-containing 90S pre-ribosomal complex subun
    2.5e-06   27.4   0.0      4e-06   26.7   0.0    1.2  1  DEAD            DEAD/DEAH box helicase
  ------ inclusion threshold ------
      0.071   13.4   0.0       0.13   12.6   0.0    1.4  1  NAD_Gly3P_dh_C  NAD-dependent glycerol-3-phosphate dehydrogen


Domain annotation for each model (and alignments):
>> CMS1  U3-containing 90S pre-ribosomal complex subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  247.7   9.9   1.8e-77   1.1e-73       6     250 ..      18     279 ..       8     281 .] 0.86

  Alignments for each domain:
  == domain 1  score: 247.7 bits;  conditional E-value: 1.8e-77
        CMS1   6 rkrkae....nkekgkkkksek..........kRskkkerkkgklketq..DvkaglteavalqdpelLadylaqklkriekDlsdveLeDkyisasai 88 
                 +krk+e      ++gkk+k  +          +++kkk+ kk   k  q  D +  + e++ +++ + Lad+  qk k  +kDl+ veL+D  ++a a+
  EEA19593.1  18 KKRKREdsdnTAQNGKKQK--GwnkdkkfnrnNKDKKKDDKKPSNKTAQqpDREEAVDESISKMNEQILADHFMQKAKAHNKDLTAVELSDMCVPAHAF 114
                 4555553332234444444..24466778766455555555544444443699999******************************************* PP

        CMS1  89 kDttsftkPrtldnlpdyleels.efakklvksaksngsPelLvltlaalRaaDlaralkklqtkdskvakLFakhikleesvtylkksrigiavGtpg 186
                 kDttsf++ r l +lp+yl+ +s e  ++l ++++ +g+P++Lv+++a+lRaaDl+ral+++q+kd  vakLFakhik+ee  ++l +sr++i+vGtp+
  EEA19593.1 115 KDTTSFEQERKLAQLPAYLKAYSpEKGARLANAPEEKGTPHTLVISSAGLRAADLVRALRSFQNKDAAVAKLFAKHIKIEEAKQFLERSRVSIGVGTPQ 213
                 ********************99636779*********************************************************************** PP

        CMS1 187 RildLleeeslsvdeLkrivlDasfvDkknrgildiretrkeviklLgakevkerle..ekkvkvv 250
                 Ri+dLle ++l+ ++L+riv+D s++D+k+rgi+d++e   +++klL+++e k r+   +k+ k++
  EEA19593.1 214 RIIDLLESGTLKTEKLERIVIDGSHIDQKKRGIFDMKEVYAPLLKLLTREEFKGRYGskDKDLKIL 279
                 *******************************************************97335555555 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.7   0.0   6.6e-10     4e-06      42     131 ..     143     238 ..     122     257 .. 0.82

  Alignments for each domain:
  == domain 1  score: 26.7 bits;  conditional E-value: 6.6e-10
                 S.....TTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEE.EEETTSSHHHHHHHHH.TTCSEEEEEHHHHHHHHHCTSSHCTTEEEEEEETHH CS
                 x.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  42 t.....kgktgpkalivePtreLaeqtlnnlkkfkkyidlrvl.liiggvaardqlskld.ngvdivvgtpgrlddllstgklnlsqvrflVlDEad 131
                 +     ++k +p +l+++     a + ++ l++f ++ d  v  l+ +  + ++ ++ l+ ++v i vgtp+r++dll++g+l++++++ +V+D  +
  EEA19593.1 143 RlanapEEKGTPHTLVISSAGLRAADLVRALRSFQNK-DAAVAkLFAKHIKIEEAKQFLErSRVSIGVGTPQRIIDLLESGTLKTEKLERIVIDGSH 238
                 0445567899*************************97.4444437777778888888886355*******************************777 PP

>> NAD_Gly3P_dh_C  NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   2.1e-05      0.13      54     120 ..     154     225 ..     139     242 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 2.1e-05
                     GGGGG.STTT..HHHHHHHHHSCT.HHHHHHHHHHCT--HHHHHH..HHCC--HHHHHHHHHHHHHHHTT.G CS
  NAD_Gly3P_dh_C  54 petfl.glag..lgDlivtctsgksRNrrfGeelgkgesleeiek..elnqvleGvetakevyellkkkgve 120
                     p+t++ ++ag   +Dl+    s + +++ +++ ++k  ++ee+++  e ++v  Gv t + +++ll++  ++
      EEA19593.1 154 PHTLViSSAGlrAADLVRALRSFQNKDAAVAKLFAKHIKIEEAKQflERSRVSIGVGTPQRIIDLLESGTLK 225
                     5555559999667*******************************9644347779**********99987664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (281 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1900  (0.105974); expected 358.6 (0.02)
Passed bias filter:                      612  (0.0341346); expected 358.6 (0.02)
Passed Vit filter:                        93  (0.00518713); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.59u 0.26s 00:00:00.85 Elapsed: 00:00:00.43
# Mc/sec: 1969.17
//
Query:       EEA19594.1  [L=298]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.3e-69  232.7  13.5    8.6e-56  189.1   9.3    2.1  2  CMS1            U3-containing 90S pre-ribosomal complex subun
    0.00095   19.0   0.0     0.0016   18.2   0.0    1.3  1  DEAD            DEAD/DEAH box helicase
  ------ inclusion threshold ------
       0.12   12.8   0.0       0.26   11.7   0.0    1.5  1  Vps54           Vps54-like protein
       0.15   12.3   0.0       0.25   11.6   0.0    1.5  1  NAD_Gly3P_dh_C  NAD-dependent glycerol-3-phosphate dehydrogen


Domain annotation for each model (and alignments):
>> CMS1  U3-containing 90S pre-ribosomal complex subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  189.1   9.3   1.9e-59   8.6e-56       6     197 ..      18     224 ..      11     231 .. 0.85
   2 !   46.0   0.1   9.1e-16   4.1e-12     187     250 ..     230     296 ..     227     298 .] 0.87

  Alignments for each domain:
  == domain 1  score: 189.1 bits;  conditional E-value: 1.9e-59
        CMS1   6 rkrkae....nkekgkkkksek..........kRskkkerkkgklketq..DvkaglteavalqdpelLadylaqklkriekDlsdveLeDkyisasai 88 
                 +krk+e      ++gkk+k  +          +++kkk+ kk   k  q  D +  + e++ +++ + Lad+  qk k  +kDl+ veL+D  ++a a+
  EEA19594.1  18 KKRKREdsdnTAQNGKKQK--GwnkdkkfnrnNKDKKKDDKKPSNKTAQqpDREEAVDESISKMNEQILADHFMQKAKAHNKDLTAVELSDMCVPAHAF 114
                 4555553332234444444..24466778766455555555544444443699999******************************************* PP

        CMS1  89 kDttsftkPrtldnlpdyleels.efakklvksaksngsPelLvltlaalRaaDlaralkklqtkdskvakLFakhikleesvtylkksrigiavGtpg 186
                 kDttsf++ r l +lp+yl+ +s e  ++l ++++ +g+P++Lv+++a+lRaaDl+ral+++q+kd  vakLFakhik+ee  ++l +sr++i+vGtp+
  EEA19594.1 115 KDTTSFEQERKLAQLPAYLKAYSpEKGARLANAPEEKGTPHTLVISSAGLRAADLVRALRSFQNKDAAVAKLFAKHIKIEEAKQFLERSRVSIGVGTPQ 213
                 ********************99636779*********************************************************************** PP

        CMS1 187 RildLleeesl 197
                 Ri+dLle +++
  EEA19594.1 214 RIIDLLESGMF 224
                 ******99887 PP

  == domain 2  score: 46.0 bits;  conditional E-value: 9.1e-16
        CMS1 187 RildLl.eeeslsvdeLkrivlDasfvDkknrgildiretrkeviklLgakevkerle..ekkvkvv 250
                 R+ +L  ++++l+ ++L+riv+D s++D+k+rgi+d++e   +++klL+++e k r+   +k+ k++
  EEA19594.1 230 RMNQLTlHQGTLKTEKLERIVIDGSHIDQKKRGIFDMKEVYAPLLKLLTREEFKGRYGskDKDLKIL 296
                 78888559************************************************97335555555 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0   3.6e-07    0.0016      42     131 ..     143     255 ..     124     271 .. 0.78

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 3.6e-07
                 S.....TTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEE.EEETTSSHHHHHHHHH.TTCSEEEEEHHHHHHHH.................HCTS CS
                 x.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxx.................xxxx RF
        DEAD  42 t.....kgktgpkalivePtreLaeqtlnnlkkfkkyidlrvl.liiggvaardqlskld.ngvdivvgtpgrlddll.................stgk 116
                 +     ++k +p +l+++     a + ++ l++f ++ d  v  l+ +  + ++ ++ l+ ++v i vgtp+r++dll                 ++g+
  EEA19594.1 143 RlanapEEKGTPHTLVISSAGLRAADLVRALRSFQNK-DAAVAkLFAKHIKIEEAKQFLErSRVSIGVGTPQRIIDLLesgmfllfnrrmnqltlHQGT 240
                 04445678999************************97.4444437777778888888886355***************888888888888777776777 PP

                 SHCTTEEEEEEETHH CS
                 xxxxxxxxxxxxxxx RF
        DEAD 117 lnlsqvrflVlDEad 131
                 l++++++ +V+D  +
  EEA19594.1 241 LKTEKLERIVIDGSH 255
                 778888888888655 PP

>> Vps54  Vps54-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   5.8e-05      0.26      36      68 ..     213     250 ..     193     253 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 5.8e-05
       Vps54  36 srllelLk.....lfNsrtcqliLgAgAtrsagLktIt 68 
                 +r+++lL+     lfN+r++ql L  g +++ +L++I 
  EEA19594.1 213 QRIIDLLEsgmflLFNRRMNQLTLHQGTLKTEKLERIV 250
                 5677777777777**********************995 PP

>> NAD_Gly3P_dh_C  NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   5.7e-05      0.25      54     116 ..     154     221 ..     139     274 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 5.7e-05
                     GGGGG.STTT..HHHHHHHHHSCT.HHHHHHHHHHCT--HHHHHH..HHCC--HHHHHHHHHHHHHHH CS
  NAD_Gly3P_dh_C  54 petfl.glag..lgDlivtctsgksRNrrfGeelgkgesleeiek..elnqvleGvetakevyellkk 116
                     p+t++ ++ag   +Dl+    s + +++ +++ ++k  ++ee+++  e ++v  Gv t + +++ll++
      EEA19594.1 154 PHTLViSSAGlrAADLVRALRSFQNKDAAVAKLFAKHIKIEEAKQflERSRVSIGVGTPQRIIDLLES 221
                     5555559999667*******************************9644346779******99999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (298 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1968  (0.109766); expected 358.6 (0.02)
Passed bias filter:                      661  (0.0368676); expected 358.6 (0.02)
Passed Vit filter:                        95  (0.00529868); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.59u 0.32s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 1976.15
//
Query:       EEA19595.1  [L=339]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-20   73.6   0.0    2.5e-20   73.0   0.0    1.3  1  Methyltransf_23  Methyltransferase domain
    1.2e-10   41.9   0.0    7.7e-09   36.2   0.0    3.2  2  Methyltransf_12  Methyltransferase domain
    1.3e-10   41.8   0.0    3.7e-10   40.4   0.0    1.8  1  Methyltransf_25  Methyltransferase domain
    7.2e-10   38.9   0.0    7.5e-09   35.5   0.0    2.1  1  Methyltransf_31  Methyltransferase domain
    3.6e-07   30.8   0.0    8.5e-07   29.5   0.0    1.7  1  Methyltransf_11  Methyltransferase domain
    0.00085   18.9   0.0     0.0098   15.5   0.0    2.1  2  MTS              Methyltransferase small domain
     0.0079   16.1   0.0        1.8    8.5   0.0    2.2  2  UPF0146          Uncharacterised protein family (UPF0146)
     0.0089   15.8   0.0      0.036   13.8   0.0    1.8  2  Methyltransf_16  Lysine methyltransferase
  ------ inclusion threshold ------
      0.042   13.3   0.6       0.12   11.8   0.0    2.1  3  Methyltransf_4   Putative methyltransferase
      0.097   12.0   0.0       0.16   11.4   0.0    1.3  1  PrmA             Ribosomal protein L11 methyltransferase (Prm


Domain annotation for each model (and alignments):
>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.0   0.0   1.4e-23   2.5e-20      20     163 ..     101     255 ..      59     257 .. 0.74

  Alignments for each domain:
  == domain 1  score: 73.0 bits;  conditional E-value: 1.4e-23
  Methyltransf_23  20 lraggrvLdiGcGtGillevlrengf..svtgvDlspeaveiae.kakkaqkdqfdeqeaaepqgkfdlIvlrevlehvpdppellrqiatllk 110
                      l  + rvLd+G+GtG ++  ++e+    +v g Dlsp++ ++ + + ++ ++d +  +e+ +  ++fd+I++r ++++++d+ +l++q+ ++l 
       EEA19595.1 101 LSNPVRVLDFGTGTGVWAIDFAEENPrtEVLGTDLSPIQPSWFPsNCRFEVDDVE--SEWLYGYQSFDYIHCRGMTGSIRDWQKLFAQAVDNLQ 192
                      44555****************8885545************997544444444444..78889999***************************** PP

  Methyltransf_23 111 pgGylllseplasl.......kedrllldw.lylvpagrhi.sffsarsl.kelleeaGlevv 163
                      pgG+++++e+  +          ++ +  w   l++a++ + + fs  sl k+ +eeaG+ ++
       EEA19595.1 193 PGGWMEVQEYEIEIssddgshLKAENFVLWkDKLNEASQMFgKPFSDYSLhKQRMEEAGFIDI 255
                      *********655444455553356666667334555555556667666663566899998666 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2   0.0   4.3e-12   7.7e-09       1      98 [.     108     196 ..     108     197 .. 0.87
   2 ?    0.9   0.0      0.44   7.9e+02      64      90 ..     284     315 ..     237     321 .. 0.72

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 4.3e-12
  Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvelealdlldldgg..ssfDlvvasnvlhhlkdirevldnirkl 92 
                      L++G+GtG  +  ++e++p++e++g+D+sp +              + +n+++e++d++++     +sfD++++ +    ++d++++++++ + 
       EEA19595.1 108 LDFGTGTGVWAIDFAEENPRTEVLGTDLSPIQP----SW-------FPSNCRFEVDDVESEWLYgyQSFDYIHCRGMTGSIRDWQKLFAQAVDN 190
                      8*****************************999....22.......334667777776665555779*************************** PP

  Methyltransf_12  93 LkpgGr 98 
                      L pgG+
       EEA19595.1 191 LQPGGW 196
                      *****8 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.44
  Methyltransf_12  64 g....ssfDlvvasnvlhhl.kdirevldnir 90 
                           + + l v   vl +  +d+re++++++
       EEA19595.1 284 MfeavEPYSLAVFTRVLKWSnEDTRELIEKVK 315
                      03334689999999999999999999999886 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.4   0.0   2.1e-13   3.7e-10       1      97 []     107     195 ..     107     195 .. 0.91

  Alignments for each domain:
  == domain 1  score: 40.4 bits;  conditional E-value: 2.1e-13
                      EEEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHHTTTTEEEEESBCCG.BSSSTTTEEEEEEESTGGGSSHHHHHHHHHHHHHHE CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlgkakvtgvDiseemleaareraeeeglnvefvqgdaed.lpfedgsfDlvvssgalhhlsdedlekalkeiarvL 93 
                      vLd+G+GtG +++++a++ ++ +v+g+D+s+ +     +++       +f++ d+e+ + +  +sfD+++++g+   +  +d++k+++++ + L
       EEA19595.1 107 VLDFGTGTGVWAIDFAEENPRTEVLGTDLSPIQPSWFPSNC-------RFEVDDVESeWLYGYQSFDYIHCRGMTGSI--RDWQKLFAQAVDNL 191
                      9*****************879***********999887766.......9******665899**********8776555..59************ PP

                      EEEE CS
  Methyltransf_25  94 kpgG 97 
                      +pgG
       EEA19595.1 192 QPGG 195
                      ***9 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.5   0.0   4.2e-12   7.5e-09       4     113 ..     104     203 ..     101     250 .. 0.82

  Alignments for each domain:
  == domain 1  score: 35.5 bits;  conditional E-value: 4.2e-12
  Methyltransf_31   4 glrvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielArenaqklgldnveFeqgdiee.leklledekfDlilsnevlnaladpdkilee 96 
                       +rvlD G+GtG  ++ +a e +p+ ev G D s+  i+ +         +n++Fe+ d+e+     +  ++fD+i++++    + d +k + +
       EEA19595.1 104 PVRVLDFGTGTGVWAIDFA-EENPRTEVLGTDLSP--IQPSWF------PSNCRFEVDDVESeWL--YGYQSFDYIHCRGMTGSIRDWQKLFAQ 186
                      689****************.88************9..666665......78***********444..7779*********************** PP

  Methyltransf_31  97 iervlkpggilliedpr 113
                      + ++l+pgg + ++++ 
       EEA19595.1 187 AVDNLQPGGWMEVQEYE 203
                      *********99999988 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.5   0.0   4.7e-10   8.5e-07       1      94 [.     108     197 ..     108     199 .. 0.90

  Alignments for each domain:
  == domain 1  score: 29.5 bits;  conditional E-value: 4.7e-10
                      EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-EEEETTEECCC.TSS-TT-EEEEEEES-CCC-CCHHHHHHHHHHHEEEE CS
  Methyltransf_11   1 LdvGcGtGrlaealakrg..arvvgvDlskemlklakekaseeglkvefvvadaek.lpfednsfDlvvssevlhhvedpekalkeiaRvLkpg 91 
                      Ld+G+GtG  a ++a+    ++v+g+Dls+ +  +  +       +++f v d+e+   +  +sfD + ++ +   + d++k++++++  L+pg
       EEA19595.1 108 LDFGTGTGVWAIDFAEENprTEVLGTDLSPIQPSWFPS-------NCRFEVDDVESeWLYGYQSFDYIHCRGMTGSIRDWQKLFAQAVDNLQPG 194
                      8**************77779************988833.......36788999997357999******************************** PP

                      EEE CS
  Methyltransf_11  92 Gll 94 
                      G++
       EEA19595.1 195 GWM 197
                      *87 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   5.5e-06    0.0098      34      64 ..     106     136 ..      89     159 .. 0.90
   2 ?    1.1   0.0      0.14   2.6e+02     118     135 ..     180     197 ..     161     203 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 5.5e-06
                 EEEEET-TTSHHHHHHHHHTTC.EEEEEESB CS
         MTS  34 kvlDlGcGaGvlgaalakespeaevtlvdvd 64 
                 +vlD+G+G+Gv ++ +a+e+p++ev  +d +
  EEA19595.1 106 RVLDFGTGTGVWAIDFAEENPRTEVLGTDLS 136
                 69**********************9998865 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.14
                 HHHHHHHHHHHEEEEEEE CS
         MTS 118 aeeliaeAkeaLkegGeL 135
                 +++l+a+A + L++gG +
  EEA19595.1 180 WQKLFAQAVDNLQPGGWM 197
                 799*************76 PP

>> UPF0146  Uncharacterised protein family (UPF0146)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.5   0.0    0.0083        15       9      74 ..      99     168 ..      94     189 .. 0.78
   2 !    8.5   0.0   0.00099       1.8      14      78 ..     270     336 ..     263     339 .] 0.87

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0083
                 HHHS-SSEEEEET-TT--HHHHHHHHHS.-EEEEE-SS-S.......STTEE---SSS--HHHHTTEEEE CS
     UPF0146   9 aeenargkvvEvGiGrkldvaealakrg.vdlvatDikek...kakegvrivrDDvtdPnleiYkgadli 74 
                 a ++++ +v + G G+ +   +   +    +++ tD+ +      + ++r+ +DDv +  l  Y++ d i
  EEA19595.1  99 APLSNPVRVLDFGTGTGVWAIDFAEENPrTEVLGTDLSPIqpsWFPSNCRFEVDDVESEWLYGYQSFDYI 168
                 5678889999999998776555555555579999996655333789**********99888888887777 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00099
                 SSEEEEET-TT--HHHHHHHHHS-EEEEE-SS-S......STTEE---SSS--HHHHTTEEEEEEES CS
     UPF0146  14 rgkvvEvGiGrkldvaealakrgvdlvatDikek..kakegvrivrDDvtdPnleiYkgadliYslR 78 
                  +++ EvG  ++ ++ ea+  ++++++   +k +   ++e ++ v+ ++ dP+ +iY     +Y  +
  EEA19595.1 270 DKRMKEVGKVQQYQMFEAVEPYSLAVFTRVLKWSneDTRELIEKVKAEICDPQYHIYSLFTFVYGRK 336
                 57999********************99888876644677999*****************99999744 PP

>> Methyltransf_16  Lysine methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.8   0.0     2e-05     0.036      45      82 ..     102     139 ..      85     152 .. 0.90
   2 ?   -1.3   0.0      0.85   1.5e+03      99     119 ..     294     314 ..     285     319 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2e-05
  Methyltransf_16  45 lsklsvlELGsGtGlvGlavaellpeakviltDleell 82 
                      +++++vl+ G GtG+  + +ae  p+++v+ tDl+ ++
       EEA19595.1 102 SNPVRVLDFGTGTGVWAIDFAEENPRTEVLGTDLSPIQ 139
                      57899****************************99876 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.85
  Methyltransf_16  99 kvkvevLdWgeeleedlleke 119
                      +v ++vL+W +e +++l+ek 
       EEA19595.1 294 AVFTRVLKWSNEDTRELIEKV 314
                      577899***999888888765 PP

>> Methyltransf_4  Putative methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   6.7e-05      0.12       4      33 ..     106     135 ..     103     139 .. 0.90
   2 ?   -2.3   0.0       1.5   2.7e+03      70      94 ..     223     247 ..     182     261 .. 0.61
   3 ?   -3.4   0.5       3.1   5.6e+03      83      91 ..     266     274 ..     265     275 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 6.7e-05
                     EEEEET-TTSHHHHHHHHHSTTSEEEEEES CS
  Methyltransf_4   4 vvleiGcGkGeflvalAkknPdknflGiEi 33 
                      vl+ G+G G + ++ A++nP +++lG ++
      EEA19595.1 106 RVLDFGTGTGVWAIDFAEENPRTEVLGTDL 135
                     589************************876 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1.5
                     TTSEEEEEEES-----SGGGGGGST CS
  Methyltransf_4  70 dgslekifilFPDPwfKkrhhKrRl 94 
                     +++l++ + +F  P+     hK+R+
      EEA19595.1 223 KDKLNEASQMFGKPFSDYSLHKQRM 247
                     3344444444555555555555555 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 3.1
                     ---SGGGGG CS
  Methyltransf_4  83 PwfKkrhhK 91 
                     Pw+K ++ K
      EEA19595.1 266 PWPKDKRMK 274
                     *****9987 PP

>> PrmA  Ribosomal protein L11 methyltransferase (PrmA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   8.8e-05      0.16     161     195 ..     103     138 ..      85     153 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 8.8e-05
        PrmA 161 egeevlDvGtGSGiLaiaaakLg.akkvvavDiDev 195
                 +  +vlD+GtG+G+ ai  a  +   +v+++D+ ++
  EEA19595.1 103 NPVRVLDFGTGTGVWAIDFAEENpRTEVLGTDLSPI 138
                 5568*************8665551678999999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (339 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       599  (0.0334096); expected 358.6 (0.02)
Passed bias filter:                      531  (0.0296168); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.47
# Mc/sec: 2186.01
//
Query:       EEA19596.1  [L=335]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.5e-20   73.6   0.0    2.4e-20   73.0   0.0    1.3  1  Methyltransf_23  Methyltransferase domain
    1.2e-10   42.0   0.0    7.5e-09   36.2   0.0    3.2  2  Methyltransf_12  Methyltransferase domain
    1.3e-10   41.8   0.0    3.7e-10   40.4   0.0    1.8  1  Methyltransf_25  Methyltransferase domain
    6.9e-10   38.9   0.0    7.4e-09   35.6   0.0    2.1  1  Methyltransf_31  Methyltransferase domain
    3.5e-07   30.8   0.0    8.3e-07   29.6   0.0    1.7  1  Methyltransf_11  Methyltransferase domain
    0.00083   18.9   0.0     0.0096   15.5   0.0    2.1  2  MTS              Methyltransferase small domain
     0.0076   16.1   0.0        1.7    8.5   0.0    2.2  2  UPF0146          Uncharacterised protein family (UPF0146)
     0.0086   15.8   0.0      0.036   13.8   0.0    1.8  2  Methyltransf_16  Lysine methyltransferase
  ------ inclusion threshold ------
      0.042   13.3   0.6       0.12   11.8   0.0    2.1  3  Methyltransf_4   Putative methyltransferase
      0.096   12.1   0.0       0.15   11.4   0.0    1.3  1  PrmA             Ribosomal protein L11 methyltransferase (Prm


Domain annotation for each model (and alignments):
>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.0   0.0   1.3e-23   2.4e-20      20     163 ..      97     251 ..      55     253 .. 0.74

  Alignments for each domain:
  == domain 1  score: 73.0 bits;  conditional E-value: 1.3e-23
  Methyltransf_23  20 lraggrvLdiGcGtGillevlrengf..svtgvDlspeaveiae.kakkaqkdqfdeqeaaepqgkfdlIvlrevlehvpdppellrqiatllk 110
                      l  + rvLd+G+GtG ++  ++e+    +v g Dlsp++ ++ + + ++ ++d +  +e+ +  ++fd+I++r ++++++d+ +l++q+ ++l 
       EEA19596.1  97 LSNPVRVLDFGTGTGVWAIDFAEENPrtEVLGTDLSPIQPSWFPsNCRFEVDDVE--SEWLYGYQSFDYIHCRGMTGSIRDWQKLFAQAVDNLQ 188
                      44555****************8885545************997544444444444..78889999***************************** PP

  Methyltransf_23 111 pgGylllseplasl.......kedrllldw.lylvpagrhi.sffsarsl.kelleeaGlevv 163
                      pgG+++++e+  +          ++ +  w   l++a++ + + fs  sl k+ +eeaG+ ++
       EEA19596.1 189 PGGWMEVQEYEIEIssddgshLKAENFVLWkDKLNEASQMFgKPFSDYSLhKQRMEEAGFIDI 251
                      *********655444455553356666667334555555556667666663566899998666 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2   0.0   4.2e-12   7.5e-09       1      98 [.     104     192 ..     104     193 .. 0.87
   2 ?    0.9   0.0      0.43   7.8e+02      64      90 ..     280     311 ..     233     317 .. 0.72

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 4.2e-12
  Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvelealdlldldgg..ssfDlvvasnvlhhlkdirevldnirkl 92 
                      L++G+GtG  +  ++e++p++e++g+D+sp +              + +n+++e++d++++     +sfD++++ +    ++d++++++++ + 
       EEA19596.1 104 LDFGTGTGVWAIDFAEENPRTEVLGTDLSPIQP----SW-------FPSNCRFEVDDVESEWLYgyQSFDYIHCRGMTGSIRDWQKLFAQAVDN 186
                      8*****************************999....22.......334667777776665555779*************************** PP

  Methyltransf_12  93 LkpgGr 98 
                      L pgG+
       EEA19596.1 187 LQPGGW 192
                      *****8 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.43
  Methyltransf_12  64 g....ssfDlvvasnvlhhl.kdirevldnir 90 
                           + + l v   vl +  +d+re++++++
       EEA19596.1 280 MfeavEPYSLAVFTRVLKWSnEDTRELIEKVK 311
                      03334689999999999999999999999886 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.4   0.0     2e-13   3.7e-10       1      97 []     103     191 ..     103     191 .. 0.91

  Alignments for each domain:
  == domain 1  score: 40.4 bits;  conditional E-value: 2e-13
                      EEEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHHTTTTEEEEESBCCG.BSSSTTTEEEEEEESTGGGSSHHHHHHHHHHHHHHE CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlgkakvtgvDiseemleaareraeeeglnvefvqgdaed.lpfedgsfDlvvssgalhhlsdedlekalkeiarvL 93 
                      vLd+G+GtG +++++a++ ++ +v+g+D+s+ +     +++       +f++ d+e+ + +  +sfD+++++g+   +  +d++k+++++ + L
       EEA19596.1 103 VLDFGTGTGVWAIDFAEENPRTEVLGTDLSPIQPSWFPSNC-------RFEVDDVESeWLYGYQSFDYIHCRGMTGSI--RDWQKLFAQAVDNL 187
                      9*****************879***********999887766.......9******665899**********8776555..59************ PP

                      EEEE CS
  Methyltransf_25  94 kpgG 97 
                      +pgG
       EEA19596.1 188 QPGG 191
                      ***9 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.6   0.0   4.1e-12   7.4e-09       4     113 ..     100     199 ..      97     246 .. 0.82

  Alignments for each domain:
  == domain 1  score: 35.6 bits;  conditional E-value: 4.1e-12
  Methyltransf_31   4 glrvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielArenaqklgldnveFeqgdiee.leklledekfDlilsnevlnaladpdkilee 96 
                       +rvlD G+GtG  ++ +a e +p+ ev G D s+  i+ +         +n++Fe+ d+e+     +  ++fD+i++++    + d +k + +
       EEA19596.1 100 PVRVLDFGTGTGVWAIDFA-EENPRTEVLGTDLSP--IQPSWF------PSNCRFEVDDVESeWL--YGYQSFDYIHCRGMTGSIRDWQKLFAQ 182
                      689****************.88************9..666665......78***********444..7779*********************** PP

  Methyltransf_31  97 iervlkpggilliedpr 113
                      + ++l+pgg + ++++ 
       EEA19596.1 183 AVDNLQPGGWMEVQEYE 199
                      *********99999988 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.6   0.0   4.6e-10   8.3e-07       1      94 [.     104     193 ..     104     195 .. 0.90

  Alignments for each domain:
  == domain 1  score: 29.6 bits;  conditional E-value: 4.6e-10
                      EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-EEEETTEECCC.TSS-TT-EEEEEEES-CCC-CCHHHHHHHHHHHEEEE CS
  Methyltransf_11   1 LdvGcGtGrlaealakrg..arvvgvDlskemlklakekaseeglkvefvvadaek.lpfednsfDlvvssevlhhvedpekalkeiaRvLkpg 91 
                      Ld+G+GtG  a ++a+    ++v+g+Dls+ +  +  +       +++f v d+e+   +  +sfD + ++ +   + d++k++++++  L+pg
       EEA19596.1 104 LDFGTGTGVWAIDFAEENprTEVLGTDLSPIQPSWFPS-------NCRFEVDDVESeWLYGYQSFDYIHCRGMTGSIRDWQKLFAQAVDNLQPG 190
                      8**************77779************988833.......36788999997357999******************************** PP

                      EEE CS
  Methyltransf_11  92 Gll 94 
                      G++
       EEA19596.1 191 GWM 193
                      *87 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   5.4e-06    0.0096      34      64 ..     102     132 ..      85     155 .. 0.90
   2 ?    1.1   0.0      0.14   2.5e+02     118     135 ..     176     193 ..     157     199 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 5.4e-06
                 EEEEET-TTSHHHHHHHHHTTC.EEEEEESB CS
         MTS  34 kvlDlGcGaGvlgaalakespeaevtlvdvd 64 
                 +vlD+G+G+Gv ++ +a+e+p++ev  +d +
  EEA19596.1 102 RVLDFGTGTGVWAIDFAEENPRTEVLGTDLS 132
                 69**********************9998865 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.14
                 HHHHHHHHHHHEEEEEEE CS
         MTS 118 aeeliaeAkeaLkegGeL 135
                 +++l+a+A + L++gG +
  EEA19596.1 176 WQKLFAQAVDNLQPGGWM 193
                 799*************76 PP

>> UPF0146  Uncharacterised protein family (UPF0146)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.5   0.0    0.0081        15       9      74 ..      95     164 ..      90     185 .. 0.78
   2 !    8.5   0.0   0.00097       1.7      14      78 ..     266     332 ..     259     335 .] 0.87

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0081
                 HHHS-SSEEEEET-TT--HHHHHHHHHS.-EEEEE-SS-S.......STTEE---SSS--HHHHTTEEEE CS
     UPF0146   9 aeenargkvvEvGiGrkldvaealakrg.vdlvatDikek...kakegvrivrDDvtdPnleiYkgadli 74 
                 a ++++ +v + G G+ +   +   +    +++ tD+ +      + ++r+ +DDv +  l  Y++ d i
  EEA19596.1  95 APLSNPVRVLDFGTGTGVWAIDFAEENPrTEVLGTDLSPIqpsWFPSNCRFEVDDVESEWLYGYQSFDYI 164
                 5678889999999998776555555555579999996655333789**********99888888887777 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00097
                 SSEEEEET-TT--HHHHHHHHHS-EEEEE-SS-S......STTEE---SSS--HHHHTTEEEEEEES CS
     UPF0146  14 rgkvvEvGiGrkldvaealakrgvdlvatDikek..kakegvrivrDDvtdPnleiYkgadliYslR 78 
                  +++ EvG  ++ ++ ea+  ++++++   +k +   ++e ++ v+ ++ dP+ +iY     +Y  +
  EEA19596.1 266 DKRMKEVGKVQQYQMFEAVEPYSLAVFTRVLKWSneDTRELIEKVKAEICDPQYHIYSLFTFVYGRK 332
                 57999********************99888876644677999*****************99999744 PP

>> Methyltransf_16  Lysine methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.8   0.0     2e-05     0.036      45      82 ..      98     135 ..      81     148 .. 0.90
   2 ?   -1.2   0.0      0.84   1.5e+03      99     119 ..     290     310 ..     281     315 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2e-05
  Methyltransf_16  45 lsklsvlELGsGtGlvGlavaellpeakviltDleell 82 
                      +++++vl+ G GtG+  + +ae  p+++v+ tDl+ ++
       EEA19596.1  98 SNPVRVLDFGTGTGVWAIDFAEENPRTEVLGTDLSPIQ 135
                      57899****************************99876 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.84
  Methyltransf_16  99 kvkvevLdWgeeleedlleke 119
                      +v ++vL+W +e +++l+ek 
       EEA19596.1 290 AVFTRVLKWSNEDTRELIEKV 310
                      577899***999888888765 PP

>> Methyltransf_4  Putative methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   6.6e-05      0.12       4      33 ..     102     131 ..      99     135 .. 0.90
   2 ?   -2.3   0.0       1.5   2.7e+03      70      94 ..     219     243 ..     178     257 .. 0.61
   3 ?   -3.3   0.5       3.1   5.5e+03      83      91 ..     262     270 ..     261     271 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 6.6e-05
                     EEEEET-TTSHHHHHHHHHSTTSEEEEEES CS
  Methyltransf_4   4 vvleiGcGkGeflvalAkknPdknflGiEi 33 
                      vl+ G+G G + ++ A++nP +++lG ++
      EEA19596.1 102 RVLDFGTGTGVWAIDFAEENPRTEVLGTDL 131
                     589************************876 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1.5
                     TTSEEEEEEES-----SGGGGGGST CS
  Methyltransf_4  70 dgslekifilFPDPwfKkrhhKrRl 94 
                     +++l++ + +F  P+     hK+R+
      EEA19596.1 219 KDKLNEASQMFGKPFSDYSLHKQRM 243
                     3344444444555555555555555 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 3.1
                     ---SGGGGG CS
  Methyltransf_4  83 PwfKkrhhK 91 
                     Pw+K ++ K
      EEA19596.1 262 PWPKDKRMK 270
                     *****9987 PP

>> PrmA  Ribosomal protein L11 methyltransferase (PrmA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   8.6e-05      0.15     161     195 ..      99     134 ..      81     150 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 8.6e-05
        PrmA 161 egeevlDvGtGSGiLaiaaakLg.akkvvavDiDev 195
                 +  +vlD+GtG+G+ ai  a  +   +v+++D+ ++
  EEA19596.1  99 NPVRVLDFGTGTGVWAIDFAEENpRTEVLGTDLSPI 134
                 5568*************8665551678999999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (335 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       584  (0.0325729); expected 358.6 (0.02)
Passed bias filter:                      516  (0.0287802); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.47
# Mc/sec: 2154.68
//
Query:       EEA19597.1  [L=352]
Description: RNA binding protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-14   52.8   0.0    7.3e-14   51.4   0.0    1.8  1  RRM_1     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom
  ------ inclusion threshold ------
      0.039   14.1   0.0       0.11   12.6   0.0    1.7  1  RRM_7     RNA recognition motif


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.4   0.0   8.1e-18   7.3e-14       1      65 [.     214     280 ..     214     283 .. 0.95

  Alignments for each domain:
  == domain 1  score: 51.4 bits;  conditional E-value: 8.1e-18
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE...TTTSEEEEEEEEESSHHHHHHHHHHHTTEEET CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd...etgkskgfafVeFeskedAekAlealngkklg 65 
                 +fVgnLp+++t e + ++Fsk+ pi s+++ +d   +++k +gf+fVeFe  + ++ +l+ +++  ++
  EEA19597.1 214 VFVGNLPYTATTESVTAHFSKISPI-SVRVATDkkdNNKKCRGFGFVEFEAYDRMQTCLKLYHHSSFD 280
                 8************************.**********************************88877765 PP

>> RRM_7  RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   1.2e-05      0.11       4      65 ..     214     269 ..     212     289 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.2e-05
       RRM_7   4 vFvGGlPiDiteeelkatfkefgkvlvdwPkkaeskkkaaenskaakgyvflvfedeksvka 65 
                 vFvG lP   t e+++a f++ ++++v     ++ ++k+       +g+ f+ fe+ + +++
  EEA19597.1 214 VFVGNLPYTATTESVTAHFSKISPISVRVATDKKDNNKK------CRGFGFVEFEAYDRMQT 269
                 9*************************9887766655543......35777777776665554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (352 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2773  (0.154666); expected 358.6 (0.02)
Passed bias filter:                      627  (0.0349713); expected 358.6 (0.02)
Passed Vit filter:                       293  (0.0163422); expected 17.9 (0.001)
Passed Fwd filter:                       131  (0.0073066); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 1.67u 0.38s 00:00:02.04 Elapsed: 00:00:00.59
# Mc/sec: 1802.33
//
Query:       EEA19598.1  [L=199]
Description: Rho GTPase Rac, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.6e-54  183.2   0.0      3e-54  183.0   0.0    1.0  1  Ras       Ras family
    2.6e-20   72.8   0.0    3.7e-20   72.3   0.0    1.2  1  Roc       Ras of Complex, Roc, domain of DAPkinase
    1.6e-07   30.9   0.0    2.1e-07   30.6   0.0    1.1  1  Arf       ADP-ribosylation factor family


Domain annotation for each model (and alignments):
>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  183.0   0.0     5e-58     3e-54       1     161 [.      11     183 ..      11     184 .. 0.98

  Alignments for each domain:
  == domain 1  score: 183.0 bits;  conditional E-value: 5e-58
                 EEEEEESTTSSHHHHHHHHHHSSCSSSCTTTSSEEEEEEEEEETTEEEEEEEEEETTSGGGHHHHHHHHTTESEEEEEEETTBHHHHHTHH.HHHHHHH CS
         Ras   1 KlvlvGdsavGKtslllrfvkdkFkeeyesTigvdfytkeievdgkevkleiwDTAGqeefkslrelyyrdaegillvyditsresfenvk.kwveeik 98 
                 K+v+ Gd+avGKt+ll++++++ F+ ey++T+ +d+y+++++vdg+ ++l +wDTAGqe++++lr+l+y +++++l++++i s  sf+nvk kw+ ei+
  EEA19598.1  11 KCVVTGDGAVGKTCLLISYTTNAFPGEYIPTV-FDNYSASVMVDGRPISLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSIVSPPSFDNVKaKWFPEIE 108
                 89******************************.****************************************************************** PP

                 HHSTTTSEEEEEEETTTGGG............G-SS-HHHHHHHHHHHT.SEEEEEBTTTTCTHHHHHHHHHHHHH CS
         Ras  99 rvaeenvpivLvGnKvDlee............kravsteegeelakelg.lkfletSAktnenveeafeellreil 161
                 ++a+  vpi+LvG+K Dl+e             + vs+e++ ++ake+   k+le+SA t+ n++ +f+e++r++l
  EEA19598.1 109 HHAP-GVPIILVGTKLDLREdrataealrakkMEPVSYEQALAVAKEIRaHKYLECSALTQRNLKSVFDEAIRAVL 183
                 ****.7************************99999**************99*********************9986 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.3   0.0   6.2e-24   3.7e-20       1     120 []      11     125 ..      11     125 .. 0.89

  Alignments for each domain:
  == domain 1  score: 72.3 bits;  conditional E-value: 6.2e-24
                 EEEEESSTTSSHHHHHHCHCT-CCC-EEETTTTEEEEEEECGGSGGCTTBTTTTCEEEEEEEE-SGGCTTTT-HHHHCTSCEEEEEEE...GHHHHCHH CS
         Roc   1 KvvlvGdsgvGKtsllkrfvedkfsekekstigvdfltkevtkikgvendkkvkkvklniWDtaGqerfrslhplylreaalailvyd...srssenlk 96 
                 K v+ Gd++vGKt+ll +++++ f  ++ +t+  +++ + +  ++g       + ++l +WDtaGqe+++ l+pl + + +++++++      s++n+k
  EEA19598.1  11 KCVVTGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSASVM--VDG-------RPISLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSivsPPSFDNVK 100
                 78999***************************999876543..444.......5799*****************************9865444788885 PP

                 .HHHHHHHHHCSSS-EEEEEE-TTT CS
         Roc  97 .eWlkelkkvagkspvilvgnkiDl 120
                  +W+ e++++a+  p+ilvg+k+Dl
  EEA19598.1 101 aKWFPEIEHHAPGVPIILVGTKLDL 125
                 38*********************95 PP

>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.6   0.0   3.5e-11   2.1e-07      12     169 ..       7     176 ..       2     182 .. 0.82

  Alignments for each domain:
  == domain 1  score: 30.6 bits;  conditional E-value: 3.5e-11
                 TTEEEEEEEESTTSSHHHHHHHHHHSSCE.ECSSSSSEEEE.EEEE..TTEEEEEEEE-SSGGGGGGGGGGCTTESEEEEEEETT-CTTHHHHHHHHHH CS
         Arf  12 kkelrilllGLDnaGKtTilkklkleelv.ttvPTigfnve.elei..knlkftvwDvGGqeklRplWknYfektdavifvvDsadreRleeakeeLka 106
                 +++l++++ G  + GKt +l  ++++ +  + +PT+  n   ++++  + +++ +wD  Gqe   +l    +++td+ + +   +    +++ k++   
  EEA19598.1   7 TQSLKCVVTGDGAVGKTCLLISYTTNAFPgEYIPTVFDNYSaSVMVdgRPISLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSIVSPPSFDNVKAKWFP 105
                 6899******9999************996269***9888542566544889************9999999***********************998766 PP

                 HCTSGCCTTSEEEEEEE-TTSTTSS-HHHHHHHTTGGGSS.........SSSSEEEEEEBTTTTBTHHHHHH CS
         Arf 107 lleeeelkevallvlaNKqDlpealseeelrellgleelk.........gkrkleiqkcsavkgeglkegle 169
                  +e+ +   v++++++ K Dl+e+  ++e  ++ ++e ++           r  +  +csa+++++lk+ ++
  EEA19598.1 106 EIEH-HAPGVPIILVGTKLDLREDRATAEALRAKKMEPVSyeqalavakEIRAHKYLECSALTQRNLKSVFD 176
                 6654.4569***************999999999999986644444444455666677888888888887776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (199 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       442  (0.0246528); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.44
# Mc/sec: 1372.01
//
Query:       EEA19599.1  [L=709]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.1e-07   28.9  10.7    9.1e-07   28.9  10.7    1.8  2  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
    2.6e-05   23.4   0.1    6.2e-05   22.2   0.1    1.6  1  Fungal_trans  Fungal specific transcription factor domain
  ------ inclusion threshold ------
       0.32    9.6   0.7       0.48    9.1   0.7    1.1  1  Rabaptin      Rabaptin


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.9  10.7   1.5e-10   9.1e-07       1      39 [.      89     134 ..      89     135 .. 0.89
   2 ?   -2.2   0.3      0.82   4.9e+03      19      24 ..     262     267 ..     257     281 .. 0.63

  Alignments for each domain:
  == domain 1  score: 28.9 bits;  conditional E-value: 1.5e-10
                 SS-HHHHHCT---ST.SSSS.......-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus   1 haCdnCrkkKvKCda.kkPa.......CsnCkklnleCtfysesskr 39 
                 +aC++C+++K +Cd  + Pa       Cs+Ck+ln +C+  ++s kr
  EEA19599.1  89 RACNECKQQKLRCDIvQAPAstsarspCSRCKRLNIDCK-VEQSFKR 134
                 69**************88888888888************.8888776 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.82
                 S-HHHH CS
     Zn_clus  19 aCsnCk 24 
                 +C++C 
  EEA19599.1 262 ECRSCS 267
                 388885 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.2   0.1     1e-08   6.2e-05       2     139 ..     241     361 ..     240     408 .. 0.76

  Alignments for each domain:
  == domain 1  score: 22.2 bits;  conditional E-value: 1e-08
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLl 98 
                   d +f+ +hp +p+l+  +  ++         +++s+ l+++++++ ++ ++ e++   s +   s            +   + s  +++ +++++L 
    EEA19599.1 241 DQYFKFYHPFLPLLDPTKDPEEC--------RSCSDVLAWTVICVSSRRCPYESGLLVSLSAPFS---------RLLWA--NISNVPQNYHVVKALC 318
                   67999999999999977666666........99*********************99866666544.........23333..344444448******* PP

  Fungal_trans  99 llelyektssdralher..hhgvavrlarslgLhrnpsyvgkk 139
                   ll+++ + ++++++     ++g++++la +lgLhr    ++ +
    EEA19599.1 319 LLCTWPLPTTSQKSDQTfmLSGLMMNLAMQLGLHRPVQPEEFT 361
                   **********988888888***************987776644 PP

>> Rabaptin  Rabaptin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.7     8e-05      0.48     140     164 ..     142     166 ..     121     176 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 8e-05
    Rabaptin 140 esaereiadlrrrlsegqeeenled 164
                   +ereiadlrrrl+ g++ e l d
  EEA19599.1 142 AEMEREIADLRRRLATGERAEGLVD 166
                 3468*************99988754 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (709 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       581  (0.0324056); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.64u 0.28s 00:00:00.92 Elapsed: 00:00:00.44
# Mc/sec: 4822.84
//
Query:       EEA19600.1  [L=669]
Description: Rho GTPase activator (Rgd1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-50  171.1   0.0    5.6e-50  169.1   0.0    2.0  2  RhoGAP        RhoGAP domain
      4e-14   52.6   0.6      4e-14   52.6   0.6    2.0  2  FCH           Fes/CIP4, and EFC/F-BAR homology domain
  ------ inclusion threshold ------
       0.13   12.6   0.2         17    5.7   0.0    2.7  2  DUF3135       Protein of unknown function (DUF3135)
        2.1    8.5   9.4        3.9    7.6   9.3    1.5  1  GIDA_assoc    GidA associated domain
          5    7.9   9.5       0.33   11.7   2.7    2.4  2  DUF4472       Domain of unknown function (DUF4472)


Domain annotation for each model (and alignments):
>> RhoGAP  RhoGAP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.1       1.3   4.7e+03      18      66 ..     203     250 ..     198     259 .. 0.65
   2 !  169.1   0.0   1.6e-53   5.6e-50       1     146 [.     491     640 ..     491     644 .. 0.98

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1.3
                 STTTTTS-S-HHHHHHHHHHHHHTGGGCTTTTTSCHHHHHHHHHHHHHH CS
      RhoGAP  18 tegiyRvsgskarvkelreafdkgkavdsdleeedvhavaslLKrfLre 66 
                 + g + ++g+k+++++ +e  +++ ++++ + + +v+a  s+ K+ L +
  EEA19600.1 203 QGGKFGLKGHKSAIQQEEEL-SRKVQNADADYQAKVQAAQSARKELLAS 250
                 55666777888888876554.4444444477777888888877777765 PP

  == domain 2  score: 169.1 bits;  conditional E-value: 1.6e-53
                 BHHHHHHHHHHHHHTTTSTTTTTS-S-HHHHHHHHHHHHHTGGGCT....TTTTSCHHHHHHHHHHHHHHSSSTTTTGGHHHHHHHHHTSSSHHHHHHH CS
      RhoGAP   1 PiivekcvefiekrgldtegiyRvsgskarvkelreafdkgkavds....dleeedvhavaslLKrfLrelpepLltkelyeelieaaksedeeerlea 95 
                 P+iv++c++++e  gld+egiyR+sgs+++++++++afd+++++++    ++  +dv++va+lLK+f+relp+pL+t+++y+++i+aa++e++ +r ++
  EEA19600.1 491 PVIVYQCIQAVEMFGLDMEGIYRQSGSANHINHMKAAFDNDSSKVDftnpESFFHDVNSVAGLLKQFFRELPDPLFTRQFYNDFINAARIENDGQRRDS 589
                 99******************************************999999999********************************************** PP

                 HHHHHTTS-HHHHHHHHHHHHHHHHHHHTHHHH---HHHHHHHHHHHHHT- CS
      RhoGAP  96 lkellekLPkenrdtLryLlehLkrvaenskenkMtaknLaivfaPtLlrp 146
                 l+++++ LP++n++tLr+L+ hL+rv+e++++n+Mta n+ai+f+PtL+  
  EEA19600.1 590 LHAIINGLPDPNYATLRALVLHLNRVQEHASNNRMTAGNIAICFGPTLMGA 640
                 ************************************************975 PP

>> FCH  Fes/CIP4, and EFC/F-BAR homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.6   0.6   1.1e-17     4e-14       1      74 [.      59     133 ..      59     136 .. 0.95
   2 ?   -3.7   0.2       4.4   1.6e+04      30      47 ..     219     236 ..     213     258 .. 0.58

  Alignments for each domain:
  == domain 1  score: 52.6 bits;  conditional E-value: 1.1e-17
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCT----TT.-.....HHHHHHHHHHHHHHHHHHHH CS
         FCH   1 gfkvlqkrleqgialledlqeflkeRaeiEkeYakkLqkLakkylkrr.kkkseestlvtawtvlleeteklaqs 74 
                 g+ +l++rl+q+ia+  d+ +flk+R+ +E+e+a+ L+kLa+++++   k +++++t ++a +++   +e++a++
  EEA19600.1  59 GVTTLLARLKQSIASARDFSTFLKKRSVLEDEHAQGLKKLARQTQEAAhKPDTRQGTYSRAQDEITRIHEQMADH 133
                 6889******************************************9999999*******************987 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 4.4
                 HHHHHHHHHHHCT----T CS
         FCH  30 EkeYakkLqkLakkylkr 47 
                 E+e ++k q+    y+ +
  EEA19600.1 219 EEELSRKVQNADADYQAK 236
                 555555555544444443 PP

>> DUF3135  Protein of unknown function (DUF3135)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.3     0.021        75      22      51 ..     239     268 ..     225     280 .. 0.84
   2 ?    5.7   0.0    0.0048        17      22      61 ..     585     624 ..     583     636 .. 0.89

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.021
     DUF3135  22 lrqelieelIesapeemqrrLrglqfqiDm 51 
                 + q++ +el++s+++++  +Lr+l f+ D 
  EEA19600.1 239 AAQSARKELLASHRPQTIHQLRQLIFECDS 268
                 567788999999999999999999999886 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.0048
     DUF3135  22 lrqelieelIesapeemqrrLrglqfqiDmqlsraknPva 61 
                  r++  +++I+  p  + + Lr+l  +++++ + a+n+  
  EEA19600.1 585 QRRDSLHAIINGLPDPNYATLRALVLHLNRVQEHASNNRM 624
                 589999*****************************99855 PP

>> GIDA_assoc  GidA associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   9.3    0.0011       3.9      59     197 ..     109     261 ..      65     263 .. 0.58

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0011
                 -HHHHHHHHHHHHHHHHHHHHHCCEEE........HHHHHHHH...HHHT....EHHHHCTTST-.-HHHHHCCHHHHHHHSCHHHHHHHHHHHCHHH. CS
  GIDA_assoc  59 seeryekfeekkeeieelkellkstkl........kseewkkl..lekkeskklslaellkrpev.kledlleelpeeeeeseeeleqveieakYegy. 145
                  ++r  ++++ ++ei++++e++++  l         s + ++l  +++k++k+ ++  l ++++v + e+l+e+++++ ++ +e+ ++v++  k  g  
  EEA19600.1 109 PDTRQGTYSRAQDEITRIHEQMADHGLqfavslyqMSVDLSELseNIEKSRKQWKASGLAAEKKVtDAEALVEKAKAKYDSLAEQYDRVKTGDKQGGKf 207
                 344444444445555555544443322212121111111222222233333333555555554442445555555555555566666666655543321 PP

                 .HHHHHHHCHHHHHHHTSB--TTS-CCC.STT--CHHHHHHHHH--SCHHHHTT CS
  GIDA_assoc 146 .iekqeeeieklkkeenlkipedldYsk.ikgLskearekLkkvrPetlgqAsr 197
                  ++ +++ i++ +++ ++  ++d dY++ ++  ++  +e L ++rP+t++q ++
  EEA19600.1 208 gLKGHKSAIQQEEELSRKVQNADADYQAkVQAAQSARKELLASHRPQTIHQLRQ 261
                 1455568888888888888899****9979999999999***********9875 PP

>> DUF4472  Domain of unknown function (DUF4472)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.3      0.79   2.8e+03      49      83 ..      93     127 ..      78     139 .. 0.61
   2 ?   11.7   2.7   9.2e-05      0.33      12      99 ..     141     228 ..     132     234 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.79
     DUF4472  49 lerekaaeeiqslrerlaeleeekkeleeeyvvlk 83 
                    +k+a++ q+++++ ++ +   +++++e + ++
  EEA19600.1  93 QGLKKLARQTQEAAHKPDTRQGTYSRAQDEITRIH 127
                 33456666666666666666666666666655554 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 9.2e-05
     DUF4472  12 LVdlqietnklreqheaekfelknkvlalenrvlelelerekaaeeiqslrerlaeleeekkeleeeyvvlkknyqalekefekekkk 99 
                 L  + +  ++l e++e+ + + k   la+e++v++ e+  eka+ + +sl+e+++ +++  k+  + +   +k+++++e+e+ ++++ 
  EEA19600.1 141 LYQMSVDLSELSENIEKSRKQWKASGLAAEKKVTDAEALVEKAKAKYDSLAEQYDRVKTGDKQGGKFGLKGHKSAIQQEEELSRKVQN 228
                 55566777899*****************************************************99999999*******999988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (669 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1339  (0.0746835); expected 358.6 (0.02)
Passed bias filter:                      618  (0.0344693); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.72u 0.29s 00:00:01.01 Elapsed: 00:00:00.49
# Mc/sec: 4120.90
//
Query:       EEA19601.1  [L=378]
Description: hypothetical protein PMAA_003860 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.043   13.7   0.4      0.077   12.9   0.4    1.4  1  DUF1348   Protein of unknown function (DUF1348)


Domain annotation for each model (and alignments):
>> DUF1348  Protein of unknown function (DUF1348)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.4   4.3e-06     0.077      80     115 ..     315     349 ..     296     365 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 4.3e-06
     DUF1348  80 vrfayeykdesgqwfrsyGnenWefdeeGlmkkrea 115
                  +fay  + +++ w+ syG   W++d++G+ ++r  
  EEA19601.1 315 YEFAYAAHGNDDVWWDSYGG-AWTLDDQGRYAERLF 349
                 479999999**********6.8*********99964 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (378 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       429  (0.0239277); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2710.54
//
Query:       EEA19602.1  [L=202]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-07   32.2   7.0     0.0001   22.8   0.5    2.3  2  HTH_32         Homeodomain-like domain
     0.0002   21.5   0.3     0.0019   18.4   0.0    2.5  2  HTH_Tnp_Tc3_2  Transposase


Domain annotation for each model (and alignments):
>> HTH_32  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.6   1.5   8.8e-06     0.079      19      71 ..       3      48 ..       1      50 [. 0.74
   2 !   22.8   0.5   1.1e-08    0.0001       1      71 [.      45     109 ..      45     110 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 8.8e-06
      HTH_32 19 drprrgrprklsdevrariiallreeprWsprqlaarlaeregvkvShstvyr 71
                +r+r  ++r l++  rari++l  +  rW+++++++        ++  st+++
  EEA19602.1  3 PRRRT-ARRELDPCMRARICELH-TSARWGYKRIHKVH-----PEIPISTIRN 48
                45444.4446*************.666*******9955.....4477777775 PP

  == domain 2  score: 22.8 bits;  conditional E-value: 1.1e-08
      HTH_32   1 TvsrwlkRyneeGlegLkdr..prrgrprklsdevrariiallreeprWsprqlaarlaeregvkvShstvyr 71 
                 T+++++k+ ++e    + +r  pr+g p+kls e+++ +i+l++e+p+  + +l++ + +    + S+ t++r
  EEA19602.1  45 TIRNTIKK-EQE---RVNQRslPRSGQPSKLSSEQKENLIQLTKENPHIKYYELQESV-DM---RCSKTTIRR 109
                 67777777.555...4444444779******************999**********99.44...49*****99 PP

>> HTH_Tnp_Tc3_2  Transposase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.1      0.11   9.9e+02      31      42 ..      42      53 ..      32      59 .. 0.79
   2 !   18.4   0.0   2.1e-07    0.0019       2      37 ..      77     109 ..      76     125 .. 0.92

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.11
  HTH_Tnp_Tc3_2 31 sreTirrrLrka 42
                     +Tir++++k+
     EEA19602.1 42 PISTIRNTIKKE 53
                   558999999987 PP

  == domain 2  score: 18.4 bits;  conditional E-value: 2.1e-07
  HTH_Tnp_Tc3_2   2 rrIvrlvrkdPritlreLanelkeeGksvsreTirr 37 
                     ++++l++++P+i + eL++++      +s++Tirr
     EEA19602.1  77 ENLIQLTKENPHIKYYELQESV---DMRCSKTTIRR 109
                    689*******************...**********8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (202 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       783  (0.0436723); expected 358.6 (0.02)
Passed bias filter:                      492  (0.0274416); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 1307.07
//
Query:       EEA19603.1  [L=481]
Description: MFS amine transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.7e-52  178.5  45.6      8e-41  140.1  24.0    2.1  2  MFS_1       Major Facilitator Superfamily
    7.7e-08   31.3  25.1    8.3e-07   27.9   5.8    2.6  3  MFS_2       MFS/sugar transport protein
    2.6e-06   26.0   7.4    4.2e-05   22.0   6.9    2.3  1  OATP        Organic Anion Transporter Polypeptide (OATP) fami
    4.6e-06   25.3  14.3     0.0032   15.9   1.2    2.5  2  MFS_3       Transmembrane secretion effector
    9.4e-05   21.4  11.4    9.4e-05   21.4  11.4    2.4  3  Sugar_tr    Sugar (and other) transporter
    0.00022   20.2   9.8    0.00022   20.2   9.8    3.1  2  MFS_1_like  MFS_1 like family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.1  24.0   2.7e-44     8e-41       2     329 ..      34     396 ..      30     406 .. 0.75
   2 !   52.5  13.7   1.2e-17   3.6e-14      44     176 ..     321     469 ..     317     480 .. 0.87

  Alignments for each domain:
  == domain 1  score: 140.1 bits;  conditional E-value: 2.7e-44
       MFS_1   2 llaaflsalarsilgpalplalaedlgispse....igllltlyalgaavaslplGrlsdrfGrrr.vlllglllfalglllll.fasslwlllvlrvl 94 
                  +a+f  ++ ++++ p++p al    ++s++     ++ ll++ ++g +v+s++ G++sd ++ rr  lllgl +++ + +++l +a+s+++++++r+l
  EEA19603.1  34 TFAVFTDIFLYGVIVPVIPFALEYRANVSVDRvqywVSVLLAVDGAGLLVFSPICGWFSDTISMRRlPLLLGLSALLGA-TVMLnVATSVTVFIIGRLL 131
                 345555555555566666655544455555556555555777788899***************8887999999999999.88886657777******** PP

       MFS_1  95 qGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllll.............peepperk 180
                 qG+ a++++ +g+al+ad +p+e  g+++g++s+g+  G++lgpllgg+l++  g+ +v+ ++ ++  l f l ++l+                     
  EEA19603.1 132 QGISAAIVWVVGLALLADTVPRELLGQYMGYVSLGMTSGFMLGPLLGGVLYERTGYNGVWALCYAFIGLDFALRIVLVekkdlpvstvpenG------- 223
                 **********************************************************************9965555555555444444430....... PP

       MFS_1 181 rkspkeee................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllag 247
                        e                                ++t  ++l p++++l +++ l+++l+a+++ ++ ++++ + lpl++ e++ ++  l++g
  EEA19603.1 224 -------EpkcsdgptpemkepslenttlpaeeptsgsppAKTITQKLPPIFTLLASRR-LLAALFASVVQAALVASFDSILPLFVDETFSWG-SLQSG 313
                 .......1345555566666677777777777777666655556666666777777777.33355555555556777****************.79999 PP

       MFS_1 248 lllallalvgailallagrlsdrlgrrrrlllallllllaalglallavt....ssavllllvlvliGfglgfvfpsllalasdla 329
                 +l+  + + +++ ++++g+l d++g   r++ + + ll++ ++++l  v+      +vll+++lv+iGf++ + fp ++a +++ +
  EEA19603.1 314 ILYLTIVIPTLV-SPVVGYLGDKYGG--RWFATAGYLLACPMFVLLRLVShnsiRQKVLLVVLLVFIGFAMTLSFPVIMAEITHIV 396
                 777666666655.59**********9..5555555555555555555555669999999999*****************9999887 PP

  == domain 2  score: 52.5 bits;  conditional E-value: 1.2e-17
       MFS_1  44 gaavaslplGrlsdrfGrrrvlllglllfalglllll.fa....sslw.lllvlrvlqGlgagalfpagaaliadwfpke.............ergrai 123
                    + s+++G+l+d++G r++  +g+ll + + ++ll ++    +    ll+vl v+ G+++ ++fp+++a i++++  +               ++a+
  EEA19603.1 321 IPTLVSPVVGYLGDKYGGRWFATAGYLLACPM-FVLLrLVshnsIRQKvLLVVLLVFIGFAMTLSFPVIMAEITHIVVAKeksrpkgsfgkggAYAQAY 418
                 567899**************************.77776644434335556***************************99889***************** PP

       MFS_1 124 gllsagfslGailgpllggllasslgWravfyilaivsllafv.lfllllpeep 176
                 gl+++gf+lG+++gp  +gl+ +++gW  + + l+++s +  v +   l++++ 
  EEA19603.1 419 GLFNMGFALGTLVGPTWAGLIKQNYGWGTATWTLGLLSGVTTVpC---LIWVDG 469
                 *****************************************8844...555544 PP

>> MFS_2  MFS/sugar transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.4   7.4   1.4e-05     0.042     249     343 ..      53     151 ..       9     156 .. 0.77
   2 ?   -2.7   0.1      0.56   1.7e+03     266     313 ..     164     212 ..     157     219 .. 0.69
   3 !   27.9   5.8   2.8e-10   8.3e-07     220     411 ..     270     464 ..     243     471 .. 0.70

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 1.4e-05
       MFS_2 249 Yyltyvlg.ngsaasvfllvv....tisallgiplwqplakrlgkkntyllgalltivllvlvlllqpsnlllflvllviagfgvgvaallpwsmladv 342
                 + l+y  + + + ++++  v+     ++ l+++p+  ++   ++ +++ ll  l+++++ +++l + ++++++f++  ++ g+++++ +++  ++lad+
  EEA19603.1  53 FALEYRANvSVDRVQYWVSVLlavdGAGLLVFSPICGWFSDTISMRRLPLLLGLSALLGATVMLNV-ATSVTVFIIGRLLQGISAAIVWVVGLALLADT 150
                 444454444444444444433200145566999*********************************.*******************************9 PP

       MFS_2 343 v 343
                 v
  EEA19603.1 151 V 151
                 7 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 0.56
       MFS_2 266 lvvtisal.lgiplwqplakrlgkkntyllgalltivllvlvlllqpsn 313
                  + ++s++ lg +l  +l  r g   +++l++++  + ++l ++l +++
  EEA19603.1 164 SLGMTSGFmLGPLLGGVLYERTGYNGVWALCYAFIGLDFALRIVLVEKK 212
                 4467777656666777888888888999999988888888888775554 PP

  == domain 3  score: 27.9 bits;  conditional E-value: 2.8e-10
       MFS_2 220 vfrnraflillllfllaalalgvlnglllYyltyvlgngsaasvfllvvtisallgiplwqplakrlgkkntyllgalltivllvlvlllqpsnlllfl 318
                 ++ +r +l+ l++ +++a+ ++   ++l ++++ +   gs  s +l+++++  +l++p++ +l  ++g +  + +g+ll+ +++vl+ l++ +++   +
  EEA19603.1 270 LLASRRLLAALFASVVQAALVASFDSILPLFVDETFSWGSLQSGILYLTIVIPTLVSPVVGYLGDKYGGRWFATAGYLLACPMFVLLRLVSHNSIRQKV 368
                 5667778888888888888899999*****************************************************************555555544 PP

       MFS_2 319 vllviagfgvgvaallpwsmladvvDygelktGkrregv.........ffavlsfisklatgiglgvsgllLsafgy.rakasvqspqvvlalrllyav 407
                 +l+v+  f+  +++l ++ ++a+++     k + r +g+         +++++ +   l+t +g         ++g+ ++  +  +++ +l+l + +++
  EEA19603.1 369 LLVVLLVFIGFAMTLSFPVIMAEITHIVVAKEKSRPKGSfgkggayaqAYGLFNMGFALGTLVGPT-------WAGLiKQNYGWGTATWTLGLLSGVTT 460
                 444444444455888888888888888888889999988343332222233333333333333333.......33333334444445555555555555 PP

       MFS_2 408 lpav 411
                 +p++
  EEA19603.1 461 VPCL 464
                 5555 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.0   6.9   1.4e-08   4.2e-05     131     358 ..     121     336 ..     111     364 .. 0.65

  Alignments for each domain:
  == domain 1  score: 22.0 bits;  conditional E-value: 1.4e-08
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 131 lvllfflaqlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllklyvdidseisltpkdprWvgaWWlgflilgvlllla 229
                  v++f+++ ll+Gi a+ ++ +G++ + D v ++    y+g+++   + G +lG llG++l +               + + g W l + ++g+  +l 
  EEA19603.1 121 SVTVFIIGRLLQGISAAIVWVVGLALLADTVPRELLGQYMGYVSLGMTSGFMLGPLLGGVLYE--------------RTGYNGVWALCYAFIGLDFALR 205
                 5679***************************************99999999999999997655..............2346677766555555443333 PP

                 xxx.......xxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 230 aip.......lffFPkelpkkkeerakkkseeesae...kkeekkkkeksksseeeelkslkdfpkalkrllknpifllvilssvfeillvaGfitFlp 318
                  ++       +   P++     e ++++  ++e +e   + +++   e+ +s +   +k++ + ++ +  ll ++ +l  +++sv+++ lva f   lp
  EEA19603.1 206 IVLvekkdlpVSTVPEN----GEPKCSDGPTPEMKEpslE-NTTLPAEEPTSGS-PPAKTITQKLPPIFTLLASRRLLAALFASVVQAALVASFDSILP 298
                 32211111114444444....3333333333222212111.1111111111111.34566666666677788888888888999999999999999999 PP

                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 319 kylEtqFslsaseAnlltGvvvipgaalGillgGllvkkl 358
                  ++ + Fs  + ++ +l  ++vip  +    + G+l  k+
  EEA19603.1 299 LFVDETFSWGSLQSGILYLTIVIPTLVS--PVVGYLGDKY 336
                 9999999999999999977777776553..3445555555 PP

>> MFS_3  Transmembrane secretion effector
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   4.4   1.5e-06    0.0046      56     198 ..      79     219 ..      61     224 .. 0.75
   2 !   15.9   1.2   1.1e-06    0.0032      60     198 ..     324     476 ..     311     480 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 1.5e-06
       MFS_3  56 LPifllsilaGalaDnfdrRkv.llavqlllalvsvlltvlaalgllspwlllaltlligiGaalndPaWqAsvgelvkrrdvpaAvaLnsvginiaRs 153
                   ++++s + G  +D+++ R++ ll + + l+ ++v+l v +     s+ + ++  ll gi aa+      A + + v+r+ + + +   s+g+     
  EEA19603.1  79 AGLLVFSPICGWFSDTISMRRLpLLLGLSALLGATVMLNVAT-----SVTVFIIGRLLQGISAAIVWVVGLALLADTVPRELLGQYMGYVSLGMTSGFM 172
                 557889999*******99888746777777777777777665.....5677788899****************************************** PP

       MFS_3 154 vGPAlgGvlvaavGaalafav..nalsylalivallrwkrevrkssl 198
                  GP lgGvl    G   ++a+  + +   + + ++l  k++ + s++
  EEA19603.1 173 LGPLLGGVLYERTGYNGVWALcyAFIGLDFALRIVLVEKKDLPVSTV 219
                 **********9999876665410222222333344444555555555 PP

  == domain 2  score: 15.9 bits;  conditional E-value: 1.1e-06
       MFS_3  60 llsilaGalaDnfdrRkvllavqlllalvsvlltvlaalgllspwlllaltlligiGaalndPaWqAsvgelvkrrd.............vpaAvaLns 145
                 l+s ++G l D++  R++  a++ll     vll ++++  + + +ll++l ++ig  ++l  P   A +  +v +++               +A  L  
  EEA19603.1 324 LVSPVVGYLGDKYGGRWFATAGYLLACPMFVLLRLVSHNSIRQKVLLVVLLVFIGFAMTLSFPVIMAEITHIVVAKEksrpkgsfgkggaYAQAYGLFN 422
                 678899*****************************************************************9865541222222222222357889*** PP

       MFS_3 146 vginiaRsvGPAlgGvlvaavGa.alafavnalsylalivallrwkrevrkssl 198
                 +g+ +   vGP  +G++    G  ++++++  ls ++ +  l+++  ++rk++l
  EEA19603.1 423 MGFALGTLVGPTWAGLIKQNYGWgTATWTLGLLSGVTTVPCLIWVDGSIRKRRL 476
                 *******************99962668999999999999999999888888776 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4  11.4   3.1e-08   9.4e-05      10     175 ..      35     196 ..      26     210 .. 0.84
   2 ?    2.8   4.2     0.014        43     291     368 ..     310     384 ..     271     408 .. 0.64
   3 ?   -1.3   7.6      0.25   7.4e+02     293     368 ..     312     384 ..     309     467 .. 0.66

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 3.1e-08
                 HHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGG CS
    Sugar_tr  10 llfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivg 108
                 +    d++++g+++ ++ fa ++ +++s++  +    ++++++++  +G ++ s + g+++d+++ +   l  ++ ++ ga ++      +sv v+i+g
  EEA19603.1  35 FAVFTDIFLYGVIVPVIPFALEYRANVSVDRVQY---WVSVLLAVDGAGLLVFSPICGWFSDTISMRRLPLLLGLSALLGATVMLNVA--TSVTVFIIG 128
                 5555699**********************97765...999999999999999999*********988887777777777776666544..49******* PP

                 HHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHH.HTSS-TTHHHHHHH CS
    Sugar_tr 109 RvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglgl.nktsnadgwrillg 175
                 R+l Gi++ ++ v+   +++   p +l g+ +++  l++t G++++  +g +l ++t+++  w +  +
  EEA19603.1 129 RLLQGISAAIVWVVGLALLADTVPRELLGQYMGYVSLGMTSGFMLGPLLGGVLyERTGYNGVWALCYA 196
                 *************************************************9999888888777766443 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.014
                 HHHHHHHHHHHHHHHHH.H..HHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTT CS
    Sugar_tr 291 lvtiivgvvnfvatfva.i..flvdrfGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfalgwg 368
                 l+++i++ + ++ t+v+ +  +l d+ G R    + a+ + ++++ +  v l lv+ ++  + v++v +++f + fa+++ 
  EEA19603.1 310 LQSGILYLTIVIPTLVSpVvgYLGDKYGGR----WFATAGYLLACPMF-VLLRLVSHNSIRQKVLLVVLLVF-IGFAMTLS 384
                 677777777777777773233555666666....33333333333333.33344444456667777776666.45666553 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.25
                 HHHHHHHHHHHHHHH.H..HHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTT CS
    Sugar_tr 293 tiivgvvnfvatfva.i..flvdrfGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfalgwg 368
                 ++i++ + ++ t+v+ +  +l d+ G R +   G + ++ +fv      l lv+ ++  + v++v +++f + fa+++ 
  EEA19603.1 312 SGILYLTIVIPTLVSpVvgYLGDKYGGRWFATAGYLLACPMFV-----LLRLVSHNSIRQKVLLVVLLVF-IGFAMTLS 384
                 5566666666666662123555666655333333333333333.....3334444346666666666666.45665543 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   9.8   7.3e-08   0.00022     259     378 ..      67     186 ..      34     193 .. 0.84
   2 ?   -0.5   7.2      0.15   4.4e+02     218     342 ..     267     396 ..     184     447 .. 0.63

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 7.3e-08
  MFS_1_like 259 ntllGslvalgvvaeiplfffaeklleklGhvkl.liiallayilrfllyaiienawlvlpievLhgisfgllwaaaveyvskiapksleatgqgllsg 356
                 ++ +++l+a+  ++ +++  +  +  +++++++l l+++l+a     +++++ +++ + ++  +L+gis +++w+++    ++ +p++l ++++g +++
  EEA19603.1  67 QYWVSVLLAVDGAGLLVFSPICGWFSDTISMRRLpLLLGLSALLGATVMLNVATSVTVFIIGRLLQGISAAIVWVVGLALLADTVPRELLGQYMG-YVS 164
                 67788888899999999999999999999999987889999999999************************************************.556 PP

  MFS_1_like 357 lyfglGralGsliGGllwdlks 378
                 l +  G  lG l+GG+l++  +
  EEA19603.1 165 LGMTSGFMLGPLLGGVLYERTG 186
                 77899*************8765 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.15
  MFS_1_like 218 llnilknpeviifllvalilgmswgiienFlflYLkelgasntllGslvalgvvaeiplfffaeklleklGhvklliialla.....yilrfllyaiie 311
                 ++ +l  +++++ l++ ++  ++++ +++ l l+ +e    ++l + ++ l+ v    +  +  +l +k+G ++  +++ l+     + lr++  ++i+
  EEA19603.1 267 IFTLLASRRLLAALFASVVQAALVASFDSILPLFVDETFSWGSLQSGILYLTIVIPTLVSPVVGYLGDKYGGRWFATAGYLLacpmfVLLRLVSHNSIR 365
                 556667777777777777777777777777777776666666666666666666666666666777777777776666655411111445555555557 PP

  MFS_1_like 312 nawlvlpievLhgisfgllwaaaveyvskia 342
                 + +l++++ v+ g+++ l + +++  + +i+
  EEA19603.1 366 QKVLLVVLLVFIGFAMTLSFPVIMAEITHIV 396
                 7777777777777777777765554444433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (481 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       737  (0.0411066); expected 358.6 (0.02)
Passed bias filter:                      297  (0.0165653); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.62u 0.25s 00:00:00.87 Elapsed: 00:00:00.43
# Mc/sec: 3356.79
//
Query:       EEA19604.1  [L=324]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.011   14.8   0.0      0.015   14.4   0.0    1.2  1  MBA1      MBA1-like protein


Domain annotation for each model (and alignments):
>> MBA1  MBA1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   8.3e-07     0.015      76     171 ..     151     252 ..      71     294 .. 0.70

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 8.3e-07
        MBA1  76 AietyvkvNkafAareleqleelvslwvkeaLkarakqlPdnvkldwelikfnsvP.......Klvslqalmipgkple.lvqlvyrfdtkQklikvdk 166
                 A+++++   + fA+ +   l   +s      L++r ++  ++  + w +++++  P       +++s  a  ip+ p   + q+v+r++ +Q++ikv k
  EEA19604.1 151 ALHNLM--YTEFARGNERVLRARCSPGLGSDLIKRIRKRNPKESFAWSIERYIRDPstfftgiRVLSDRATVIPDLPDSsIRQIVLRIKSQQSFIKVAK 247
                 444444..35688888888888899999999999998888899999*999999999666666668999999****9999788***************99 PP

        MBA1 167 ksskv 171
                 + + +
  EEA19604.1 248 EDKDA 252
                 88754 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (324 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       447  (0.0249317); expected 358.6 (0.02)
Passed bias filter:                      416  (0.0232026); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.47
# Mc/sec: 2075.71
//
Query:       EEA19605.1  [L=427]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.6e-13   51.0   9.2    1.6e-13   51.0   9.2    2.4  3  EOS1          N-glycosylation protein
  ------ inclusion threshold ------
       0.23   10.6   9.4       0.34   10.1   9.4    1.2  1  SOG2          RAM signalling pathway protein
        3.6    7.1  19.4        6.7    6.2  19.4    1.5  1  Pneumo_att_G  Pneumovirinae attachment membrane glycoprotein 


Domain annotation for each model (and alignments):
>> EOS1  N-glycosylation protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.2      0.15   9.2e+02     112     134 ..     100     141 ..      23     166 .. 0.56
   2 !   51.0   9.2   2.7e-17   1.6e-13       3      82 ..     279     360 ..     277     367 .. 0.88
   3 ?   -1.8   0.0      0.42   2.5e+03     161     174 ..     380     393 ..     363     394 .. 0.81

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.15
        EOS1 112 l.....................eskasslrqgksrhkrsvskse 134
                 l                     e  ++ ++q++++h+ + ++++
  EEA19605.1 100 LpsspetprnprstapgltsmhE--QRGSHQRNATHHATIQQTT 141
                 04444444444444444444221..2222222222222222222 PP

  == domain 2  score: 51.0 bits;  conditional E-value: 2.7e-17
        EOS1   3 eyvlaslWslvsaylayslldsLlvrWlvyYsilaaliRllslqaiiwplvllllsvlsad..keqplaaWivisttltlse 82 
                 e +la +W+ +sayl+y ++d ++ rWl+ Ys  a liRll+ + +i  l++ +l + +a+      l aWi i ttlt+ +
  EEA19605.1 279 EVALAIMWCCASAYLSYFFMDCMMSRWLLNYSPPAVLIRLLATNGLIAYLTSSVLWLSGASsdPRLLLPAWISITTTLTFLY 360
                 667999*****************************************9999887776666522567899**********987 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 0.42
        EOS1 161 vgvlsfltmviLlr 174
                 + v+s+++m  +l+
  EEA19605.1 380 LSVASYISMSLILL 393
                 47899999988775 PP

>> SOG2  RAM signalling pathway protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   9.4   5.7e-05      0.34     224     380 ..      54     231 ..       3     243 .. 0.42

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 5.7e-05
        SOG2 224 eqGaalt..plrsd.qipfnl.......srsrrssssgnsaspaangaqsetsersasssgvqssasstPlgegstspp.galsrqslsttgststlts 311
                 + G a +    +s  ++   +       +       ++n++ p+++ a+s+t +  +s + +++++ st +g +s  +  g+++r+++   + ++t++ 
  EEA19605.1  54 NHGGATEedTTTSTgDNLS-SsieydiiA-------HTNGLYPQSQSAKSNTGPLPSSPE-TPRNPRSTAPGLTSMHEQrGSHQRNATHHATIQQTTRG 143
                 2333333221122211111.112222221.......233333333333333322222211.22222222222222222224444444433333333333 PP

        SOG2 312 ssksrs..........ssrsntnasastprslattpappasaesf...astltasrintlaa....vDeq..lletletavklalvvy 380
                 ++++++          +sr+ +n+s+ +  + ++ +app++ +++   ++t +as+  + +a    vD +  l  ++ +a ++ +  +
  EEA19605.1 144 EQQQQQprpyepvankQSRTYKNPSHPPQTPRMEGRAPPPTQTEAspaTPTVSASKLHPRVAvilgVDRKwyLPLVVCRALSVGPALW 231
                 3333335666677655666666888777777777777777777764432222244444444466668877554455555555555555 PP

>> Pneumo_att_G  Pneumovirinae attachment membrane glycoprotein G
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2  19.4    0.0011       6.7     207     310 ..      91     190 ..      41     203 .. 0.66

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0011
  Pneumo_att_G 207 ataklllastesvlte.dt.atskssepqleprpsqrGkstsdkeassttsqdsstrgdskkhtqrrktppatenrrsilstatppettkiqetrkp 301
                    +ak   + t+++ ++ +t  +++s+ p l+   +qrG    +++a+  +  +++trg+++++++r+  p a +++r+ ++ + pp+t+ + e+r+p
    EEA19605.1  91 QSAK---SNTGPLPSSpETpRNPRSTAPGLTSMHEQRGSH--QRNATHHATIQQTTRGEQQQQQPRPYEPVANKQSRTYKNPSHPPQTP-RMEGRAP 181
                   2333...333332222022033444555555555555543..34444445567889**********************98888887776.99****9 PP

  Pneumo_att_G 302 tpkptaelk 310
                    p +t    
    EEA19605.1 182 PPTQTEASP 190
                   999887633 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (427 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       962  (0.0536561); expected 358.6 (0.02)
Passed bias filter:                      484  (0.0269954); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.58u 0.31s 00:00:00.88 Elapsed: 00:00:00.44
# Mc/sec: 2886.99
//
Query:       EEA19606.1  [L=120]
Description: translation initiation factor SUI1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.5e-28   97.9   3.6    4.7e-28   97.5   3.6    1.2  1  SUI1          Translation initiation factor SUI1
  ------ inclusion threshold ------
      0.097   12.9   0.5       0.15   12.3   0.5    1.3  1  GlcNAc-1_reg  Putative GlcNAc-1 phosphotransferase regulatory


Domain annotation for each model (and alignments):
>> SUI1  Translation initiation factor SUI1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.5   3.6   5.3e-32   4.7e-28       2      73 ..      26      98 ..      25     103 .. 0.93

  Alignments for each domain:
  == domain 1  score: 97.5 bits;  conditional E-value: 5.3e-32
        SUI1  2 kpkihirleqrggrKkvTtvsgleafgidlkklakelkkkfacsgsvvkdg..geeiqvQGdqrkkvaelLtek 73
                +++ihir++qr+grK++Ttv+gl ++++d kk++k +kkkfac+g++v+d+  ge+iq+QGdqrk+v+e+L++k
  EEA19606.1 26 QNYIHIRIQQRNGRKTLTTVQGL-PKKFDQKKILKVIKKKFACNGTIVNDSemGEVIQLQGDQRKDVQEFLVDK 98
                789********************.*************************77345******************98 PP

>> GlcNAc-1_reg  Putative GlcNAc-1 phosphotransferase regulatory domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.5   1.7e-05      0.15      10      80 ..      42     111 ..      39     117 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.7e-05
  GlcNAc-1_reg  10 lvllsglPatfketnelkskLeeklaekvkllelylekrvalldlndfkdldeLlkddkknvtidndelrL 80 
                   l  + glP++f++ +++   ++ k+a     ++      v  l+ ++ kd++e+l d+k+ + +d +++++
    EEA19606.1  42 LTTVQGLPKKFDQ-KKILKVIKKKFACNGTIVNDSEMGEVIQLQGDQRKDVQEFLVDKKEGLELDAKTIKV 111
                   67899********.7788899***********9999999*****************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (120 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       784  (0.043728); expected 358.6 (0.02)
Passed bias filter:                      429  (0.0239277); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.46
# Mc/sec: 790.45
//
Query:       EEA19607.1  [L=114]
Description: translation initiation factor SUI1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.1e-28   98.1   3.6    4.1e-28   97.7   3.6    1.2  1  SUI1          Translation initiation factor SUI1
  ------ inclusion threshold ------
      0.081   13.2   0.4       0.13   12.5   0.4    1.3  1  GlcNAc-1_reg  Putative GlcNAc-1 phosphotransferase regulatory


Domain annotation for each model (and alignments):
>> SUI1  Translation initiation factor SUI1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.7   3.6   4.5e-32   4.1e-28       2      73 ..      26      98 ..      25     103 .. 0.93

  Alignments for each domain:
  == domain 1  score: 97.7 bits;  conditional E-value: 4.5e-32
        SUI1  2 kpkihirleqrggrKkvTtvsgleafgidlkklakelkkkfacsgsvvkdg..geeiqvQGdqrkkvaelLtek 73
                +++ihir++qr+grK++Ttv+gl ++++d kk++k +kkkfac+g++v+d+  ge+iq+QGdqrk+v+e+L++k
  EEA19607.1 26 QNYIHIRIQQRNGRKTLTTVQGL-PKKFDQKKILKVIKKKFACNGTIVNDSemGEVIQLQGDQRKDVQEFLVDK 98
                789********************.*************************77345******************98 PP

>> GlcNAc-1_reg  Putative GlcNAc-1 phosphotransferase regulatory domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.4   1.4e-05      0.13      10      80 ..      42     111 ..      39     113 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.4e-05
  GlcNAc-1_reg  10 lvllsglPatfketnelkskLeeklaekvkllelylekrvalldlndfkdldeLlkddkknvtidndelrL 80 
                   l  + glP++f++ +++   ++ k+a     ++      v  l+ ++ kd++e+l d+k+ + +d +++++
    EEA19607.1  42 LTTVQGLPKKFDQ-KKILKVIKKKFACNGTIVNDSEMGEVIQLQGDQRKDVQEFLVDKKEGLELDAKTIKV 111
                   67899********.7788899***********9999999*****************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (114 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       732  (0.0408277); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.38u 0.28s 00:00:00.66 Elapsed: 00:00:00.42
# Mc/sec: 808.45
//
Query:       EEA19608.1  [L=219]
Description: hypothetical protein PMAA_003920 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.12   12.5   0.0        0.2   11.7   0.0    1.4  1  AWS       AWS domain


Domain annotation for each model (and alignments):
>> AWS  AWS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   1.1e-05       0.2       1      17 [.     107     124 ..     107     126 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 1.1e-05
         AWS   1 Ddepsgcgs.dCiNRmll 17 
                 D ep g+g+ +CiNR+l+
  EEA19608.1 107 DNEPIGHGQlRCINRALQ 124
                 899************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (219 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       228  (0.0127168); expected 358.6 (0.02)
Passed bias filter:                      204  (0.0113782); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.24s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 1594.17
//
Query:       EEA19609.1  [L=2642]
Description: RNA polymerase II mediator complex component Srb8, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.4e-53  179.9   0.0    1.8e-51  175.3   0.0    2.6  1  p450          Cytochrome P450
    3.1e-27   94.6   0.0    8.1e-27   93.3   0.0    1.8  1  Med12         Transcription mediator complex subunit Med12
     0.0012   17.8   0.0     0.0028   16.6   0.0    1.6  1  Med12-LCEWAV  Eukaryotic Mediator 12 subunit domain


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  175.3   0.0     3e-55   1.8e-51       6     460 ..    1703    2176 ..    1693    2179 .. 0.81

  Alignments for each domain:
  == domain 1  score: 175.3 bits;  conditional E-value: 3e-55
                  EHHCCHCHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHHHHH CS
        p450    6 plplvgnllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkklRrfl 102 
                  ++p+v +ll     + l +  r++++kygp+fr+ + + ++    + ea+  ++  ++ ++ ++ +++ + + ++ +  + + ++n + + ++R ++
  EEA19609.1 1703 RIPFVYHLLR----GSLIKSQRRFHNKYGPVFRMAPDEVSF---ASEEAFYDIYTWRAGHKRAM-RDPAFFQPPEGQADNLITTNNVKFHARIRGLM 1791
                  4566666655....4466669***********988766444...45778888888777666666.5555555576666666666677********** PP

                  HHHHTSHSTT.THHHHHHHHHHHHHHHHHCCCCHCS......EEETHHHHHHHHHHHHHHHHHSSHHHTTTSSH.................HHHHHH CS
        p450  103 tptltsfgkl.sleelveeeaedlveklrkkagess......elditellskaaldvigsilFgarfdlledek.................lselvk 175 
                    ++t   +l +  +l+e  a+ l+ +l+++a++s+       +++t++++ +++dv+ +++  + f +++                      e+ +
  EEA19609.1 1792 SHSFTEE-SLyEQAPLIEGHADVLISQLQQRATSSEnlesgaLVNVTDWVNFFTMDVVRDCAKPNVFLCYTILTssqigdlalgedfgclvKGEYHD 1887
                  *******.99999***********************9**9999******************98877766654445569*************778888 PP

                  HHHHHHHHHHCHHHHC.CCCCHHHTCCSCH.HHHHHHHHHHHHHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHH CS
        p450  176 aveelssllskssvql.lllfpllkylptk.llrklkeavkklkdlldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlel 270 
                  ++++l++ l++        + p++++l++k + + +k+  k+ ++++   i+ r ++  +    r df+  +++     +  +++s+ee+  +   +
  EEA19609.1 1888 WIRTLFQYLKAMTIAAaPRYWPVMQFLFEKaIPKSIKDDAKRHQQYAYDRINRRLDSKTD----RQDFITPFMKHN--PNF-ENMSREEILSSFSFV 1977
                  888888877665544404444566666665145556666666677777777776665555....59*********5..333.69************* PP

                  HHHHHHHHHHHHHHHHHHHH..HSHHHHHHHHHHHHHHCCTTT..T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS.CEEETTEEE-TT-E CS
        p450  271 lfaGvdTtsstlswaLyeLa..knPevqeklreEidevlgdkr..eptyddlqklpyldavikEtLRlhpvvplllpRevtk.dvvirgylipkGte 362 
                  +++G++T ++ l+  + +La  +n+ + ++l++Ei+++ +  +  +++   ++klpyl+avi+E LR+ ++vp++lpR v+    +  g  +p Gt+
  EEA19609.1 1978 IIGGTETIATSLTGLFNHLAmpQNKAILDRLTKEIRSTYKTEDdiTVESITRAKLPYLEAVIQEGLRICHPVPSGLPRIVPPgGDEYTGIWLPGGTR 2074
                  ****************98876689***************66662456666789***************************99899************ PP

                  EEEEHHHHHT-TTTSSSTTS--GGGGB-TTS....CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGEEESSC.SSEE CS
        p450  363 vivnlyalhrdpevfpnPeeFdpeRFldekg....nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdpppileks.glll 454 
                    v + a++r+ ++f++P++F p+R+l++ +     ++ +  a+ PFG G ++C+G+ lA +e++l+l+++L  F++   + ++    ++ + ++++
  EEA19609.1 2075 LGVRIFAVNRSAKYFQDPDTFVPDRWLPDGErpseYDNDNLSASKPFGVGFHSCLGKLLALVEIRLVLTRILWAFDIAEEE-GMHVHFDDFPvMMMV 2170
                  *****************************8899994458999************************************755.444444444446666 PP

                  ESSSSE CS
        p450  455 ppkpik 460 
                   ++p++
  EEA19609.1 2171 EKQPLM 2176
                  666655 PP

>> Med12  Transcription mediator complex subunit Med12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.3   0.0   1.4e-30   8.1e-27       1      63 []     271     333 ..     271     333 .. 0.99

  Alignments for each domain:
  == domain 1  score: 93.3 bits;  conditional E-value: 1.4e-30
       Med12   1 fkpPsrvtlndakrenwlkdLadpsvpLtrLsrsvPhgfrgekLlemllrksVpisRAvWfir 63 
                 fkpP+rvtl+d+kre+wl+dLa++svpL+rLsr++Phg+rg+ Ll+++l k Vpi RAvW+ +
  EEA19609.1 271 FKPPPRVTLTDNKREAWLRDLANSSVPLRRLSRTIPHGIRGKVLLDQCLGKGVPIGRAVWLAK 333
                 89**********************************************************987 PP

>> Med12-LCEWAV  Eukaryotic Mediator 12 subunit domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   4.6e-07    0.0028     309     363 ..     618     672 ..     608     761 .. 0.86

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 4.6e-07
  Med12-LCEWAV 309 PvldeneseeekveFtnLVlLFseLirhDVFSHdaYmctLiSRGdlasessatln 363
                   P l++++ +++ ++ tn  ++ +eLir   FS   Y+  L+ RG +++  ++ ++
    EEA19609.1 618 PFLTQTSMDQSTSSLTNVYHIIVELIRSQTFSVGRYLQWLVARGAVEQYRQQYSQ 672
                   89999999*************************************9988777553 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2642 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       654  (0.0364772); expected 358.6 (0.02)
Passed bias filter:                      566  (0.031569); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 1.34u 0.32s 00:00:01.66 Elapsed: 00:00:00.54
# Mc/sec: 14657.42
//
Query:       EEA19610.1  [L=433]
Description: glucan endo-1,3-alpha-glucosidase agn1 precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.9e-131  438.4   8.2   2.1e-131  438.2   8.2    1.0  1  Glyco_hydro_71  Glycosyl hydrolase family 71
  ------ inclusion threshold ------
      0.015   14.7   0.0      0.026   13.8   0.0    1.4  1  ThiG            Thiazole biosynthesis protein ThiG


Domain annotation for each model (and alignments):
>> Glyco_hydro_71  Glycosyl hydrolase family 71
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  438.2   8.2  2.4e-135  2.1e-131       1     374 [.      39     407 ..      39     408 .. 0.98

  Alignments for each domain:
  == domain 1  score: 438.2 bits;  conditional E-value: 2.4e-135
  Glyco_hydro_71   1 VfaHfmvgntenytasdwekDiklAkaagiDgFaLNigskdswtaeqladayeaAeavgfkLflSfDmavagawpk...sevislikkyashpaq 92 
                     VfaHfmvg++e+yt +dw++D+++A ++giD+FaLN++s ds+t++qla ay+aAe+vgfk+f+SfD+a+   w +   +++++++++ya+h aq
      EEA19610.1  39 VFAHFMVGIVEKYTLDDWKSDMTTAMDIGIDAFALNCASVDSYTPTQLALAYQAAEEVGFKVFISFDFAY---WTNgdtANITQYMQTYAGHAAQ 130
                     9********************************************************************8...666666**************** PP

  Glyco_hydro_71  93 lkvngkplvSTFeGeknaedwasiksalteeiffvPdfsslgaaaaaekaldvvDGlfsWeaWpkgatn......mstetDeaylsalkgkpYmm 181
                     +++n+ ++vSTF G++   dw+ +k++++++i+ +P+++  ++a++++ a+ +vDG+fsW aWp+++ n      ++t  D++y+s l++ +Ym+
      EEA19610.1 131 MQYNDAAVVSTFVGDSF--DWTPVKAGTNHSIWALPNLQ--DPAEWSSDAQRSVDGAFSWYAWPTDGGNsiisgpVTTIWDDRYISDLGNATYMA 221
                     ***************99..********999*********..8889999999****************888******************99***** PP

  Glyco_hydro_71 182 pvSpwffthlgkesynknwvwrgddlwakRweqvlelqpdfveiitWNDygEShYigplkekkaqdgsskyvegmpHdgwrdllkyyiaayKtgs 276
                     pvSpwf th+++    knwv+ ++dl ++Rw ++l++qpd+veiitWNDygEShYigp++ ++++dgss++++g+pHd+wrdl+k+yi+ayK+g+
      EEA19610.1 222 PVSPWFSTHFNT----KNWVFICEDLPTRRWDEILSMQPDLVEIITWNDYGESHYIGPYSAAHSDDGSSEWASGFPHDAWRDLYKPYIQAYKSGA 312
                     **********66....******************************************************************************* PP

  Glyco_hydro_71 277 kkpaitedklvlwyRphpkkakcssgdttgnpanaelleDkvfvvallkspatvtvsvggkesetfsvkaGvnklsvpfngetGkvkvsvvrngk 371
                     ++p+i+++++v+wyRp+pk ++c ++dt+  p++++ll+D++fv+++lk++at+tv++gg++  +++v+aG+++ +v++   +G++++ ++r+g+
      EEA19610.1 313 SAPTIDTEEIVYWYRPTPKGVTC-TNDTLPAPNGINLLSDSIFVATMLKEAATLTVTSGGNALVSIDVPAGITTSNVTM--GVGEQSFVLSRDGQ 404
                     ***********************.88*************************************99**************..9************* PP

  Glyco_hydro_71 372 tva 374
                     t++
      EEA19610.1 405 TIL 407
                     996 PP

>> ThiG  Thiazole biosynthesis protein ThiG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   2.9e-06     0.026     187     231 ..      57     101 ..      18     110 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2.9e-06
                 HHHHHHHHHTT-SEEEESHHHHTSSSHHHHHHHHHHHHHHHHHHH CS
        ThiG 187 psdaaqamelGadavllntavaeakdpvamArafklaveaGrlay 231
                  sd ++am++G+da  ln a   +  p ++A a+++a e G   +
  EEA19610.1  57 KSDMTTAMDIGIDAFALNCASVDSYTPTQLALAYQAAEEVGFKVF 101
                 5899*********************************99998766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (433 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       335  (0.0186848); expected 358.6 (0.02)
Passed bias filter:                      261  (0.0145574); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.31s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 2844.46
//
Query:       EEA19611.1  [L=330]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.7e-10   41.9   0.0    2.3e-10   41.4   0.0    1.2  1  Abhydrolase_6  Alpha/beta hydrolase family
    1.5e-05   24.4   0.0    2.1e-05   23.9   0.0    1.2  1  Hydrolase_4    Serine aminopeptidase, S33
  ------ inclusion threshold ------
      0.012   15.3   0.0      0.032   13.9   0.0    1.8  2  Abhydrolase_1  alpha/beta hydrolase fold
        0.1   11.8   0.0       0.15   11.2   0.0    1.2  1  DUF2920        Protein of unknown function (DUF2920)


Domain annotation for each model (and alignments):
>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.4   0.0   5.2e-14   2.3e-10       1     218 [.      41     312 ..      41     314 .. 0.56

  Alignments for each domain:
  == domain 1  score: 41.4 bits;  conditional E-value: 5.2e-14
                    EEEE--GC.....GCHHHHHHHHCCT..........CEEEEE--TTST.S-GGCS--HHHCHHHHHHHCCTT................TTSEEEEE CS
  Abhydrolase_6   1 vlllHGagssassWlvapLaallaag..........vhvlapDlpGhG.rsdpppldledladlaalldelaa..............gggpvvlvG 71 
                    v++l G+  ++ +W   p+++   ++             l +D+ G G +++ p+++  d+ d  + l+ l+               +  p++ v+
     EEA19611.1  41 VVFLSGLTDPRKIWT--PMLRVIKEDgwvqgifqpaM--LLYDRFGSGeTAEIPATEIHDAMDATNDLRNLIVgvsekhlkivpneiDSLPIIFVA 132
                    799***9999****7..66444455555455544444..79*******33344445554443333333333335666888899999999999**** PP

                    ETCHHHHHHHHHHCC.......EE.EEES-...----TTT.S----TTHHHHHHTT-CCCCHCCH.....S-HSCCCCHHHCCCCHCHCCCGHHHH CS
  Abhydrolase_6  72 HSlGGalalaaapla.....lvvg.vlldppp.talpagl.laaalelllallallrllawlsre.....plprlfladedadaawrarlarlaal 154
                     S+GG++a +   +a      v+g +lldp p  +++ ++ +++ ++ +++ + +    + + r+      ++ ++ ++++     +  ++ l+ +
     EEA19611.1 133 LSFGGVIAEL---YAkkypsTVIGlLLLDPAPtDTDGESWlPNPDAPDFKPETLPDGVTTIMLRKaraqhRAS-PYNPNTP--NKEGIKWDNLSTY 222
                    **********...777779988889*****6643333333433333333322222222222222222222111.4444444..5555555555555 PP

                    CCHHC.HTTCCHHTT-TTGCEEECTT-C.....................HHHHCHHCCCHSTTEEET......................CE...SS CS
  Abhydrolase_6 155 laglg.llpaaawadlpvpllvlggeDp.....................lvprllerllaqagarlp......................vvlpgaG 206
                     + +g +    +w+ +p ++++  + Dp                                                             +v +g+G
     EEA19611.1 223 IPEVGrPQLMGPWKKMPLLTIM--THDPvpfaeqvdkltgipalltltyN----------------SpkwfiyleklanlvpshlrkgpIVAKGSG 300
                    5555533346688888877744..77776554444444433322222221................02222222233333334444455******* PP

                    S-HHHHSHHHHH CS
  Abhydrolase_6 207 Hlphleepdeva 218
                    H++ le+p+ va
     EEA19611.1 301 HFIPLEQPRLVA 312
                    *88888**9998 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.0   4.7e-09   2.1e-05      34     110 ..      75     160 ..      71     203 .. 0.85

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 4.7e-09
  Hydrolase_4  34 vyalDhrGhGrse.gkrghvpsfddyvdDlaafvekvkeehpel........plfllGhSmGGliallyllrypdkvaglilsaPa 110
                  ++ +D  G G+++     ++++  d ++Dl+ ++  v e+h +         p++ ++ S GG+ia ly+++yp+ v gl l  Pa
   EEA19611.1  75 MLLYDRFGSGETAeIPATEIHDAMDATNDLRNLIVGVSEKHLKIvpneidslPIIFVALSFGGVIAELYAKKYPSTVIGLLLLDPA 160
                  6789********95445589*************9444444433333336778******************************9887 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   7.2e-06     0.032       2     113 ..      40     166 ..      39     211 .. 0.70
   2 ?   -2.4   0.0      0.65   2.9e+03     229     256 ..     277     307 ..     273     308 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 7.2e-06
                    EEEEE-STTTCGGGGTTGHHHHHHHHT.......TSEEEEEEETTSTTSSSTTTGB...........CHHSHHHHHHHHHHHHHHCTTSSEEEEEE CS
  Abhydrolase_1   2 vlvilhGlpgssdvwaerglapaLakd.......gfdvillDlrGvgySspapacin..........ddygtasvaddldrildalgddkltlvGh 80 
                    ++v+l Gl++   +w    + + + +d       +   +l+D  G+g++   pa+             +      ++ l+ + +  +  +++ v+ 
     EEA19611.1  40 LVVFLSGLTDPRKIWTP--MLRVIKEDgwvqgifQPAMLLYDRFGSGETAEIPATEIhdamdatndlRNLIVGVSEKHLKIVPNEIDSLPIIFVAL 133
                    67777777777777777..7777777777777666677777777777777766642244444443333335555566666667777777899**** PP

                    THHHHHHHHHHHHHGGGEEEEEEESECSSCCHH CS
  Abhydrolase_1  81 SmGGmialayaaeyperVkalvllgaidpaasl 113
                    S+GG ia  ya +yp+ V +l ll++ ++  + 
     EEA19611.1 134 SFGGVIAELYAKKYPSTVIGLLLLDPAPTDTDG 166
                    *************************93333333 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.65
                    HHHHHHHCHTS...EEEEEEETCSSSHHHHS CS
  Abhydrolase_1 229 aledlaqllpk...krlvvisdagHlafleg 256
                    +le+la+l p+   k  +v  ++gH++ le 
     EEA19611.1 277 YLEKLANLVPShlrKGPIVAKGSGHFIPLEQ 307
                    6789999977766678889999999998875 PP

>> DUF2920  Protein of unknown function (DUF2920)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   3.4e-05      0.15     178     209 ..     115     155 ..      92     158 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 3.4e-05
     DUF2920 178 a.........dlpviliGgsyGGYlalLiaKiaPwyvdgvl 209
                            lp+i++  s+GG +a+L aK  P +v g+l
  EEA19611.1 115 HlkivpneidSLPIIFVALSFGGVIAELYAKKYPSTVIGLL 155
                 223333444468***********************998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (330 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       373  (0.0208043); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 2246.25
//
Query:       EEA19612.1  [L=74]
Description: hypothetical protein PMAA_003960 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (74 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       327  (0.0182386); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.36u 0.25s 00:00:00.61 Elapsed: 00:00:00.39
# Mc/sec: 564.62
//
Query:       EEA19613.1  [L=318]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.4e-15   57.1   0.3    3.1e-15   56.7   0.3    1.2  1  Glyco_hydro_18  Glycosyl hydrolases family 18


Domain annotation for each model (and alignments):
>> Glyco_hydro_18  Glycosyl hydrolases family 18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.7   0.3   1.7e-19   3.1e-15       5     230 ..      39     256 ..      35     308 .. 0.72

  Alignments for each domain:
  == domain 1  score: 56.7 bits;  conditional E-value: 1.7e-19
                     EEEGGGGGSS.G.C......SHTTTESEEEEEEEEEEETTTEEEESS.TTHHHHHHHHHHHH.HHTSTT-EEEEEEEETTTTTHHHHHHTSHHHH CS
                     xxxxxxxxxx.x.x......xxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18   5 Yysswesygn.n.y......lpsaklthiiyaFakidgengkvvvsd.wedlgnfeqlkklk.kkknpgvkvllsiGGwtdssgfslaastdasr 89 
                     Y+++ ++    n +       + ++lth+i+a +++d+  +++ + d   +  +  +l  ++ ++++ gvkv+l +GG+++ ++++++ +   + 
      EEA19613.1  39 YVQTFTDR-SgNwFnltdlvTQNTGLTHLILASLHLDN-PTQIHLNDnDIESAYWDPLWPMVsSLQAAGVKVMLMMGGAAR-GSYANL-Q--NDF 127
                     55444333.22332333444559*************99.557777776666689999999999****************98.677777.4..468 PP

                     HHHHHHHHHHHHHCT-SEEEEEES-TTTSTCHHHHHHHHHHHHHHHHHHHHHHTSTTCEEEEEEESSHHH....HHHH.......CHHHHHHHHT CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxx.......xxxxxxxxxx RF
  Glyco_hydro_18  90 kkfadsvvsllrkygfDGiDidweypggnpedkenytallkelrealdkakategkkllLsaavpasasd....lskg.......ydlpkiakyl 173
                     +++   + s+l+++++DG+D+d e    n++  +   +l+++l +    +    g++++L+aa+ a   +    l+++                 
      EEA19613.1 128 DTYYPIILSILKNHNLDGFDMDVE---ENVS-ESVLLRLAQQLDA----D---MGSDFILTAAPVALSMSnggnLDNVswpaldqV--------A 203
                     9***********************...2233.5556666666666....2...4799*******9998885444444455554440........4 PP

                     ...........SEEEEETTTSSSTTSSBE--SS-SSBTCSSHHHHHHHHHHTT--GGGEEEEEESEEE CS
                     ...........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18 174 ...........DyvnvmtYDfhgswdnvtghhaplydaslnvdeavkeylkagvpakklvlGvpfygr 230
                                 + n ++YD  gs                 + ++++++++ag +++++vlGv +++ 
      EEA19613.1 204 isserpngklfNWYNTQFYDGWGS---------------AATTDSYDTVISAGWDPSRIVLGVLTSAT 256
                     444445556669999999987775...............56666788899************977644 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (318 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       408  (0.0227564); expected 358.6 (0.02)
Passed bias filter:                      350  (0.0195214); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 2085.25
//
Query:       EEA19614.1  [L=369]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (369 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       363  (0.0202465); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 2461.15
//
Query:       EEA19615.1  [L=345]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.7e-10   39.4   0.0    8.8e-10   38.6   0.0    1.4  1  HNH_2     HNH endonuclease


Domain annotation for each model (and alignments):
>> HNH_2  HNH endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.6   0.0   4.9e-14   8.8e-10       9      72 .]     142     219 ..     116     219 .. 0.86

  Alignments for each domain:
  == domain 1  score: 38.6 bits;  conditional E-value: 4.9e-14
       HNH_2   9 p....slleaAHIiP............wslssffndlilnrfeigrillekgstidspsNgllLspdiHklFdqflfafe 72 
                 +    s+le++HI+P            w+++++f+    ++ +++r+ l++++++ s  N l++++ +Hk+++  lfa++
  EEA19615.1 142 RlrtgSVLENSHIYPdsmgplenrqafWERLELFW--PKEKVDQWRRILDTPEGTGSLVNTLTMNTLAHKAWGEALFALK 219
                 14443589*******99999888888888888888..88888899*********************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (345 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       282  (0.0157287); expected 358.6 (0.02)
Passed bias filter:                      242  (0.0134977); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.47
# Mc/sec: 2218.27
//
Query:       EEA19616.1  [L=429]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.2e-14   51.7   0.0    1.5e-13   50.7   0.0    1.6  1  HNH_2     HNH endonuclease


Domain annotation for each model (and alignments):
>> HNH_2  HNH endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.7   0.0   8.3e-18   1.5e-13       1      72 []     172     253 ..     172     253 .. 0.91

  Alignments for each domain:
  == domain 1  score: 50.7 bits;  conditional E-value: 8.3e-18
       HNH_2   1 CvitgiddpslleaAHIiP............wslssffndlilnrfeigrillekgstidspsNgllLspdiHklFdqflfafe 72 
                 C+it+i++ ++le+AHI+P            w+++++f+  ++++ +++ +ll + ++++s  N +++++++Hk+++q lfa++
  EEA19616.1 172 CIITQIENWAVLENAHIYPnslgptgyklelWDRLRLFW--SEEKVNKWESLLGTLQGTESLLNTITMNTMVHKAWGQALFALK 253
                 9****555559********99999998888888888888..99999************************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (429 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       515  (0.0287244); expected 358.6 (0.02)
Passed bias filter:                      306  (0.0170673); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.47
# Mc/sec: 2738.37
//
Query:       EEA19617.1  [L=326]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.5e-21   74.1   0.2    4.7e-17   62.1   0.0    2.2  2  adh_short     short chain dehydrogenase
    1.4e-10   41.1   0.0    2.3e-08   33.9   0.0    2.3  2  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
     0.0014   18.5   0.0     0.0025   17.8   0.0    1.4  1  KR            KR domain
  ------ inclusion threshold ------
       0.03   14.0   0.0      0.049   13.3   0.0    1.3  1  ATP-synt_ab   ATP synthase alpha/beta family, nucleotide-bind


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.1   0.0   1.1e-20   4.7e-17       1     125 [.      25     149 ..      25     156 .. 0.88
   2 !    9.9   0.0    0.0001      0.45     148     189 ..     196     241 ..     183     245 .. 0.76

  Alignments for each domain:
  == domain 1  score: 62.1 bits;  conditional E-value: 1.1e-20
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHT...TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGG CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvv.vdrseekleevakelkee...gakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfse 95 
                 ++++vtG   GIG+++a+ +++ +a  v+ + r+  k  ++a ++ +         ++++D+t++++v+ + e+a   l++ld+LvnNAGi     + +
  EEA19617.1  25 QTIIVTGSNVGIGLETARYFVSLDAAKVIlAVRNTTKGDQAARSITQSpgrIGVTEVWPLDLTKYHSVKLFAERA-ISLERLDILVNNAGI----LVYD 118
                 589*******************99766654999**************9643334899************999999.579************....5777 PP

                 CSHHH.HHHHHHHHTHHHHHHHHHHHHHHHH CS
   adh_short  96 lseee.wervievNltgvflltravlpamlk 125
                 ++ +e  e++i vN ++++ll+ ++lp++ +
  EEA19617.1 119 FEVAEdNESTITVNAVSAMLLSILLLPKLRD 149
                 8877779********************9864 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.0001
                 HHHHHHHHHHHHHHHHHHHHGGGT....EEEEEEEESSBSSHHHHH CS
   adh_short 148 aYsAsKaavagltrslakelaptg....irvnavaPGlvdTdmake 189
                  Y  sK     ++r+la+++ ++     i+v++ +PG+v+T++++ 
  EEA19617.1 196 RYFVSKMVQLLMIRELANQITSSAlpgnITVSVANPGFVKTEVMRH 241
                 5777777777777777777776655555**************9876 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.9   0.0   5.1e-12   2.3e-08       5     120 ..      35     150 ..      31     170 .. 0.79
   2 !    5.1   0.0    0.0033        15     137     182 ..     193     242 ..     182     265 .. 0.82

  Alignments for each domain:
  == domain 1  score: 33.9 bits;  conditional E-value: 5.1e-12
                   SHHHHHHHHHHHTT-.EEEEEESSGGH.HHHHHHHHHHTT....SEEEE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHH CS
  adh_short_C2   5 gIGraiAkalaeeGa.evvltdlneea.kkrveelaeelg....aevlecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreef 95 
                   gIG ++A+ + +  a +v+l+ +n  + ++++++++++ g    +ev ++D t+  +v+ ++e++  ++++lDilvnnagi      +f+    e+ 
    EEA19617.1  35 GIGLETARYFVSLDAaKVILAVRNTTKgDQAARSITQSPGrigvTEVWPLDLTKYHSVKLFAERAI-SLERLDILVNNAGILVY---DFE--VAEDN 125
                   9*********9987526999999999977888888877664443347***********98888877.589*************9...443..35778 PP

                   HHHHHHHTHHHHHHHHHHHHHCTSC CS
  adh_short_C2  96 draldvnlyslfllakaalplmkeg 120
                   + ++ vn+ s++ll+  +lp ++++
    EEA19617.1 126 ESTITVNAVSAMLLSILLLPKLRDT 150
                   899**********999999866654 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0033
                   TTTHHHHHHHHHHHHHHHHHHHHGG....GTEEEEEEEE--BHCTGGGGS CS
  adh_short_C2 137 nynaygaaKaalealtrylAvelgp....kgiRvNavspgpikTlaasgi 182
                     n y ++K     ++r lA+++ +     +i+v +  pg++kT+ ++++
    EEA19617.1 193 MKNRYFVSKMVQLLMIRELANQITSsalpGNITVSVANPGFVKTEVMRHA 242
                   567899999999999****998765222279*************998765 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   5.6e-07    0.0025       2      92 ..      26     115 ..      25     135 .. 0.82

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 5.6e-07
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE----- CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvl 92 
                 t ++tG   g+Gle+ar  ++  a++++l  R+ ++ +++++ i++   +    ev ++D+++ ++v+   e++  + +++   ++ Ag+l
  EEA19617.1  26 TIIVTGSNVGIGLETARYFVSLDAAKVILAVRNTTKGDQAARSITQSPGRIGVTEVWPLDLTKYHSVKLFAERAI-SLERLDILVNNAGIL 115
                 679******************************8888888888888887766679999*******9987777665.555777777777776 PP

>> ATP-synt_ab  ATP synthase alpha/beta family, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   1.1e-05     0.049      92     156 ..      36     103 ..      24     151 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.1e-05
                  HHHHHHHHHHH.TTSEEEEEEETHHHHHHHHHHHHHHTTTSBEGGGSBTTHHHHHH..HHHTTSEEET CS
                  xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxx RF
  ATP-synt_ab  92 tgitlAEyfrd.qgknvlliadslsrwaeAlreislrlgempadqgypaylgakla..slyERagkap 156
                  +g+ +A yf      +v+l + ++++  +A r i  + g++  ++ +p +l + ++   + ERa +++
   EEA19617.1  36 IGLETARYFVSlDAAKVILAVRNTTKGDQAARSITQSPGRIGVTEVWPLDLTKYHSvkLFAERAISLE 103
                  78999******9999************************************9877622699**99983 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (326 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       522  (0.0291148); expected 358.6 (0.02)
Passed bias filter:                      465  (0.0259356); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2249.68
//
Query:       EEA19618.1  [L=271]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.6e-17   61.9   0.0      1e-16   61.0   0.0    1.3  1  DUF3425   Domain of unknown function (DUF3425)


Domain annotation for each model (and alignments):
>> DUF3425  Domain of unknown function (DUF3425)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.0   0.0   5.7e-21     1e-16      18     119 ..     157     248 ..     147     252 .. 0.89

  Alignments for each domain:
  == domain 1  score: 61.0 bits;  conditional E-value: 5.7e-21
     DUF3425  18 lpenlrPtelQlriaHpveidvlpwpelRdrllrafqeeeidedeffrdvvs...........tlivWsieeeeletaeissaelsagdvtdlegWelk 105
                 +p++lr t+lQ  +++p +id++p p++Rd+ ++   ++ + ++e+  d+++           + +vW                   +d++d+++Wel+
  EEA19618.1 157 VPPTLRRTALQQSVPYPEWIDLIPSPQMRDNAIK--TQHLFTNKELAADLLTgimgqedrkdaGILVW-------------------SDPWDPSSWELT 234
                 8*********************************..6667**********987777788888888888...................59********** PP

     DUF3425 106 esFfrkYpylvdgl 119
                 e F++k+  lv+g+
  EEA19618.1 235 EGFVKKWGFLVQGC 248
                 ************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (271 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       404  (0.0225333); expected 358.6 (0.02)
Passed bias filter:                      293  (0.0163422); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 1960.26
//
Query:       EEA19619.1  [L=138]
Description: hypothetical protein PMAA_004040 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0011   19.4   0.9     0.0011   19.4   0.9    1.6  2  DUF3632   Protein of unknown function (DUF3632)


Domain annotation for each model (and alignments):
>> DUF3632  Protein of unknown function (DUF3632)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.9   6.2e-08    0.0011     104     174 ..       7      77 ..       1      80 [. 0.63
   2 ?   -1.7   0.0      0.18   3.3e+03      19      31 ..     113     125 ..     100     136 .. 0.49

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 6.2e-08
     DUF3632 104 eeeeeeaekeekldadlaaAaqWillageeLyelseeekdkdekdee.......gnagapgplwkgfskeRWafWker 174
                 + e+++++ +   da +  AaqWil++g++L++l++  ++    +++        ++g+p p+     k  W  Wk++
  EEA19619.1   7 DVEDHSQDTSRICDAWVLGAAQWILWNGQQLFKLVNWREE--LGTSSalverhrDENGNPIPK-----KHCWDDWKRG 77 
                 4456666788889999999***************544333..333333466555444555554.....4455555554 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.18
     DUF3632  19 vellkalrk..deee 31 
                  + +++lr+  +  e
  EEA19619.1 113 HREIAELREkqK--E 125
                 444444554221..1 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (138 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       748  (0.0417201); expected 358.6 (0.02)
Passed bias filter:                      416  (0.0232026); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.41
# Mc/sec: 1014.88
//
Query:       EEA19620.1  [L=651]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.022   14.6   0.0      0.053   13.3   0.0    1.7  1  RRM_1     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0     3e-06     0.053       1      58 [.     324     390 ..     324     404 .. 0.75

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 3e-06
                 EEEESETTTSSHHHHHHHHHT.TSCEEEEEEEEE........TTTSEEEEEEEEESSHHHHHHHHHH CS
       RRM_1   1 lfVgnLppdvteeeLkelFsk.fGpiksiklvrd........etgkskgfafVeFeskedAekAlea 58 
                 lfVg+Lp  +t e L + ++k f p+ ++k+  +         t +s +++ +++++  +A+kAl+ 
  EEA19620.1 324 LFVGDLPIRMTTEALGDALGKrFSPFGDCKVNVTwrlkggtdGTVRSLPTGWIQYKNVFEAAKALDV 390
                 8**********99998886666666666666655555577778899******************973 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (651 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       476  (0.0265492); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.25s 00:00:00.82 Elapsed: 00:00:00.41
# Mc/sec: 4709.09
//
Query:       EEA19621.1  [L=324]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.4e-08   33.1   0.1    1.6e-07   31.8   0.1    1.6  1  PhyH      Phytanoyl-CoA dioxygenase (PhyH)


Domain annotation for each model (and alignments):
>> PhyH  Phytanoyl-CoA dioxygenase (PhyH)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.8   0.1     9e-12   1.6e-07       2     204 ..      29     246 ..      28     253 .. 0.81

  Alignments for each domain:
  == domain 1  score: 31.8 bits;  conditional E-value: 9e-12
                 HHHSEEEETTSS-HHHHHHHHHHHHHHHHHCHTTCCSEEEEECEEESTTCCCEECCCHHCHHHHTTHHHHHHHHHHHHTSCEEEEEEEEEEEEE..EEE CS
        PhyH   2 eedGylviegflsaeevealraeiealldralesgdkidfffeekaaadedglleksinkvghflhprkvadlvrailgqdvyvaavlqsmyqd..ifk 98 
                  ++Gyl +++++++e+ +++++++     r  +s+++++++  e+ +   +++   + ++ + +++ ++v++  +++l ++++    +++ +     +k
  EEA19621.1  29 MKYGYLRVPNCFTPEKAAEWTKDVWT---RLGYSPTDKETWTSERIHMPPHRHEPVKSFAPKAWAAICEVVGGEDRVLDEAAV----WNDALIVnlGTK 120
                 689***********888888888877...89******************9999988888888888877777777777777765....677776667788 PP

                 -TTTCB-E......EEEE-SGGGST..EESGCCEEEEEEESS-B-TTBT-EEEETTG......GGS-CCGTCCHHCSGCCTTS..........CCCTTT CS
        PhyH  99 qpkiGgev......qpwHqDstflp..tdpeesvvgvwialedateenGclrfiPGS......Hkweegplrrrlpeddteae..........ddeakk 173
                 +++ G+++      + wH D  f+    d +e+ + v   + d+ e++G++ + P S      H    + + +++  +  +++            ++  
  EEA19621.1 121 EAE-GKPWphpkelYGWHVDGDFFIhfLDSREQGLLVIPLFNDIVEHAGGTVVCPDSiphmarH---LYNHPEGVSPHMVPRGgelepeykdgFYTRII 215
                 875.998888888889****88876565558999999999*****************5532222...33455666666666669999999877667777 PP

                 GHGSCEEEE.BTTTEEEEEETTSEEEE-TB. CS
        PhyH 174 edeeeavpvevkaGdavlfhgrllHgsgaNr 204
                 ++ +e+ +++ kaGd++l h+ ++H ++ N+
  EEA19621.1 216 SQCSEFHEMTGKAGDVILLHPLTVHSASVNT 246
                 8899***********************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (324 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       443  (0.0247086); expected 358.6 (0.02)
Passed bias filter:                      395  (0.0220313); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.31s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 2103.77
//
Query:       EEA19622.1  [L=324]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.4e-08   33.1   0.1    1.6e-07   31.8   0.1    1.6  1  PhyH      Phytanoyl-CoA dioxygenase (PhyH)


Domain annotation for each model (and alignments):
>> PhyH  Phytanoyl-CoA dioxygenase (PhyH)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.8   0.1     9e-12   1.6e-07       2     204 ..      29     246 ..      28     253 .. 0.81

  Alignments for each domain:
  == domain 1  score: 31.8 bits;  conditional E-value: 9e-12
                 HHHSEEEETTSS-HHHHHHHHHHHHHHHHHCHTTCCSEEEEECEEESTTCCCEECCCHHCHHHHTTHHHHHHHHHHHHTSCEEEEEEEEEEEEE..EEE CS
        PhyH   2 eedGylviegflsaeevealraeiealldralesgdkidfffeekaaadedglleksinkvghflhprkvadlvrailgqdvyvaavlqsmyqd..ifk 98 
                  ++Gyl +++++++e+ +++++++     r  +s+++++++  e+ +   +++   + ++ + +++ ++v++  +++l ++++    +++ +     +k
  EEA19622.1  29 MKYGYLRVPNCFTPEKAAEWTKDVWT---RLGYSPTDKETWTSERIHMPPHRHEPVKSFAPKAWAAICEVVGGEDRVLDEAAV----WNDALIVnlGTK 120
                 689***********888888888877...89******************9999988888888888877777777777777765....677776667788 PP

                 -TTTCB-E......EEEE-SGGGST..EESGCCEEEEEEESS-B-TTBT-EEEETTG......GGS-CCGTCCHHCSGCCTTS..........CCCTTT CS
        PhyH  99 qpkiGgev......qpwHqDstflp..tdpeesvvgvwialedateenGclrfiPGS......Hkweegplrrrlpeddteae..........ddeakk 173
                 +++ G+++      + wH D  f+    d +e+ + v   + d+ e++G++ + P S      H    + + +++  +  +++            ++  
  EEA19622.1 121 EAE-GKPWphpkelYGWHVDGDFFIhfLDSREQGLLVIPLFNDIVEHAGGTVVCPDSiphmarH---LYNHPEGVSPHMVPRGgelepeykdgFYTRII 215
                 875.998888888889****88876565558999999999*****************5532222...33455666666666669999999877667777 PP

                 GHGSCEEEE.BTTTEEEEEETTSEEEE-TB. CS
        PhyH 174 edeeeavpvevkaGdavlfhgrllHgsgaNr 204
                 ++ +e+ +++ kaGd++l h+ ++H ++ N+
  EEA19622.1 216 SQCSEFHEMTGKAGDVILLHPLTVHSASVNT 246
                 8899***********************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (324 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       443  (0.0247086); expected 358.6 (0.02)
Passed bias filter:                      395  (0.0220313); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 2194.37
//
Query:       EEA19623.1  [L=624]
Description: hypothetical protein PMAA_004070 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (624 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       939  (0.0523733); expected 358.6 (0.02)
Passed bias filter:                      504  (0.0281109); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.72u 0.35s 00:00:01.06 Elapsed: 00:00:00.50
# Mc/sec: 3782.31
//
Query:       EEA19624.1  [L=356]
Description: complex I intermediate associated protein (Cia30), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.4e-39  135.6   0.0    5.7e-26   91.4   0.0    2.1  2  CIA30            Complex I intermediate-associated protein 30
  ------ inclusion threshold ------
      0.085   12.6   0.0       0.25   11.0   0.0    1.8  1  Cation_ATPase_N  Cation transporter/ATPase, N-terminus


Domain annotation for each model (and alignments):
>> CIA30  Complex I intermediate-associated protein 30 (CIA30)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.4   0.0   6.4e-30   5.7e-26       2     110 ..      47     169 ..      46     179 .. 0.95
   2 !   42.1   0.0   9.4e-15   8.4e-11     108     160 .]     224     276 ..     217     276 .. 0.92

  Alignments for each domain:
  == domain 1  score: 91.4 bits;  conditional E-value: 6.4e-30
       CIA30   2 dFkspesldkwtllsDrvmGGvStaslklskk....dktalFsGnlstel.....inrgGFasvrt......kkrkrkldlssyegleLrvkGDgrkYk 85 
                 dF++++ +++++++ Dr +GG+S+a l++ ++      +a+F+G +st+l     ++r+G+a +r        +++  +d++ y++l+Lrvk+Dgr+Y+
  EEA19624.1  47 DFENEDAVASCKTMADRAVGGFSKADLDFVPAtahePAHARFHGSISTKLpdnwrVERTGYAAFRNrdrgywLFGRLFWDVDPYNYLALRVKSDGRRYT 145
                 8****************************988777679**********************************9************************** PP

       CIA30  86 lnlkteskeqsglsyqadfetkkge 110
                 +n+++e+   +++++q++++t+ ++
  EEA19624.1 146 VNIQSETI-VDTDIHQHRLYTRHHR 169
                 ******99.***********98764 PP

  == domain 2  score: 42.1 bits;  conditional E-value: 9.4e-15
       CIA30 108 kgewetvkipfsdfvptfrGrvvedqeeldlskiksiglllsdkqegpfeLei 160
                 ++ wetv +pf++fv+t++G +ve q++l  ++iksig+ l+d+ egp++L i
  EEA19624.1 224 TSGWETVLLPFASFVRTNHGLIVEPQHSLIKNRIKSIGIGLTDRIEGPYDLRI 276
                 344************************************************87 PP

>> Cation_ATPase_N  Cation transporter/ATPase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   2.8e-05      0.25      18      39 ..     282     303 ..     274     314 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 2.8e-05
  Cation_ATPase_N  18 enGLtqaeaaerlkkyGpNelk 39 
                      +nGL+++e +e ++ +G+N+l 
       EEA19624.1 282 TNGLSEEELEEERRICGENALL 303
                      79*****************995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (356 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       299  (0.0166769); expected 358.6 (0.02)
Passed bias filter:                      266  (0.0148363); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.30s 00:00:00.82 Elapsed: 00:00:00.49
# Mc/sec: 2183.81
//
Query:       EEA19625.1  [L=789]
Description: anaphase-promoting complex subunit Apc5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-35  120.8   3.4    1.9e-35  120.8   3.4    2.1  2  ANAPC5    Anaphase-promoting complex subunit 5
    4.1e-06   26.5   0.2    0.00073   19.3   0.1    2.7  2  TPR_10    Tetratricopeptide repeat
    0.00023   21.4   7.6      0.039   14.2   0.1    4.1  5  TPR_12    Tetratricopeptide repeat
    0.00033   21.1   0.2        1.3    9.6   0.0    4.0  4  TPR_19    Tetratricopeptide repeat
     0.0018   18.3   0.3       0.23   11.8   0.2    3.7  3  TPR_8     Tetratricopeptide repeat
  ------ inclusion threshold ------
       0.02   14.9   0.1        1.8    8.8   0.1    3.4  3  TPR_7     Tetratricopeptide repeat
      0.025   15.2   0.2       0.25   12.0   0.4    2.7  2  TPR_16    Tetratricopeptide repeat
      0.028   14.5   0.1       0.19   11.9   0.1    2.5  2  TPR_2     Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> ANAPC5  Anaphase-promoting complex subunit 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  120.8   3.4   8.5e-39   1.9e-35       1      93 [.     270     359 ..     270     360 .. 0.99
   2 ?   -2.8   0.1         3   6.8e+03      45      66 ..     558     583 ..     531     599 .. 0.66

  Alignments for each domain:
  == domain 1  score: 120.8 bits;  conditional E-value: 8.5e-39
      ANAPC5   1 hllsylnalrakdYqqaldsLhryFDyvlsqnessqkksyqyalLnlaslhadfghneeAvkaleeairlArenkDkscLalalawlarllkk 93 
                 h++++l+a++a dY++++d+LhryFDy+++++++s   +yqyalLnla+lhadfg + eA++a++eai++Are++D++cL+++++wl+++ k+
  EEA19625.1 270 HYIRFLDAWKAGDYPSSFDNLHRYFDYTVHSRDRS---FYQYALLNLAILHADFGSYTEALSAMQEAISIARESHDMNCLNFCMSWLYHFGKA 359
                 9**********************************...****************************************************885 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 3
      ANAPC5  45 Lnlaslhadf....ghneeAvkalee 66 
                 L+l  l+ +f    gh+ +A++ +e 
  EEA19625.1 558 LQLSFLEIEFrlrkGHHSQAIAIVEG 583
                 44555555555555888888865543 PP

>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.1   3.3e-07   0.00073       4      34 ..     309     339 ..     308     342 .. 0.94
   2 ?    4.3   0.0     0.018        39       8      26 ..     645     663 ..     640     666 .. 0.90

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 3.3e-07
      TPR_10   4 slnNLanalrqrgrydeAealleealairrr 34 
                 +l NLa+++ + g y+eA+  ++ea++i r+
  EEA19625.1 309 ALLNLAILHADFGSYTEALSAMQEAISIARE 339
                 789*************************998 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.018
      TPR_10   8 LanalrqrgrydeAealle 26 
                 La +l +++++++A++++e
  EEA19625.1 645 LATVLLSMREFEAAVEMME 663
                 9****************98 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.0       7.2   1.6e+04      59      72 ..      59      72 ..      54      75 .. 0.58
   2 !   14.2   0.1   1.8e-05     0.039      47      77 .]     309     339 ..     277     342 .. 0.71
   3 ?   -3.3   0.0       5.2   1.2e+04       9      35 ..     605     631 ..     599     633 .. 0.81
   4 !    7.4   0.0    0.0024       5.4       9      49 ..     645     683 ..     638     691 .. 0.91
   5 ?    1.0   0.3      0.24   5.3e+02      24      76 ..     732     782 ..     728     782 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 7.2
      TPR_12 59 gryeeAlelleeal 72
                ++++  l++lee+l
  EEA19625.1 59 KKHAVSLDALEEVL 72
                45556666666655 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 1.8e-05
      TPR_12  47 tlrnLgrlyralgryeeAlelleealaiaek 77 
                 +l nL++l+  +g y eAl++ +ea+ ia++
  EEA19625.1 309 ALLNLAILHADFGSYTEALSAMQEAISIARE 339
                 5566666666666666666666666666553 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 5.2
      TPR_12   9 laavlrrlgrydeAlellekaleiarr 35 
                  a +l + g  +  ++l  +a  ia r
  EEA19625.1 605 KARILEKTGLPQRGFSLAMRAASIAHR 631
                 688899999999999999999999865 PP

  == domain 4  score: 7.4 bits;  conditional E-value: 0.0024
      TPR_12   9 laavlrrlgrydeAlellekaleiarrllGpdhpltattlr 49 
                 la+vl+ + +++ A e+ e  + ++ +   +d++lta+++ 
  EEA19625.1 645 LATVLLSMREFEAAVEMMESIMPQVLEF--DDRYLTARSYS 683
                 9************************888..9********97 PP

  == domain 5  score: 1.0 bits;  conditional E-value: 0.24
      TPR_12  24 ellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                 ++ + +++ ++++  +d ++ ++ +   +++ +++g++  A ++  + l++++
  EEA19625.1 732 AYIDCSYDEYEAI--EDLLGQCEMMAKKATVMHLSGDLVLANDYASKYLDLRR 782
                 6777888889999..9999999999999*****************99999986 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.0     0.017        38      24      52 ..     306     334 ..     277     342 .. 0.76
   2 ?    0.6   0.0      0.38   8.5e+02      26      54 ..     479     507 ..     471     515 .. 0.82
   3 ?   -0.8   0.0         1   2.3e+03       4      53 ..     571     586 ..     553     613 .. 0.65
   4 !    9.6   0.0   0.00059       1.3      22      54 ..     636     668 ..     624     680 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.017
      TPR_19  24 naearllLAeallalgqldeAealLdalp 52 
                 +++a+l+LA+++   g ++eA  +++++ 
  EEA19625.1 306 YQYALLNLAILHADFGSYTEALSAMQEAI 334
                 78899999999999999999998888765 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.38
      TPR_19  26 earllLAeallalgqldeAealLdalpee 54 
                  ++++  ++ l  g ++ A a Ld++++ 
  EEA19625.1 479 KIAYRSSQLILHCGSYKRAVARLDDIGPT 507
                 567777788899999*********99875 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 1
      TPR_19   4 egdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpe 53 
                  g + +A+a+ e +                                   +
  EEA19625.1 571 KGHHSQAIAIVEGI----------------------------------AQ 586
                 45555555555554..................................33 PP

  == domain 4  score: 9.6 bits;  conditional E-value: 0.00059
      TPR_19  22 pknaearllLAeallalgqldeAealLdalpee 54 
                 p+ +ea   LA +ll++ ++++A ++++ ++++
  EEA19625.1 636 PGLWEAIGVLATVLLSMREFEAAVEMMESIMPQ 668
                 667899999*********************987 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   0.2    0.0001      0.23       3      33 ..     309     339 ..     308     340 .. 0.94
   2 ?   -0.7   0.0         1   2.3e+03       2      29 ..     600     627 ..     599     629 .. 0.75
   3 ?    1.5   0.0       0.2   4.5e+02       6      25 ..     644     663 ..     640     665 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.0001
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAkeyyekaleldpd 33 
                 a++nl+ ++ + g y eA +++++a++++++
  EEA19625.1 309 ALLNLAILHADFGSYTEALSAMQEAISIARE 339
                 789*************************985 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 1
                 CHHHHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8   2 eayynlgsiylklgdyeeAkeyyekale 29 
                 ++++ +++i++k+g  +   +  ++a +
  EEA19625.1 600 RLLCFKARILEKTGLPQRGFSLAMRAAS 627
                 78999********987766666666655 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.2
                 HHHHHHHHTT-HHHHHHHHH CS
       TPR_8   6 nlgsiylklgdyeeAkeyye 25 
                  l+ ++l++ ++e+A+e +e
  EEA19625.1 644 VLATVLLSMREFEAAVEMME 663
                 689999***********987 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   0.1   0.00079       1.8       1      34 [.     309     342 ..     309     344 .. 0.87
   2 ?   -2.5   0.0       3.2   7.2e+03      11      23 ..     570     582 ..     567     594 .. 0.77
   3 ?    1.9   0.0      0.13   2.9e+02       4      23 ..     644     663 ..     641     676 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00079
       TPR_7   1 aLlnLarlysrlGdyeeAielyeqsLaltkdped 34 
                 aLlnLa l+ + G y eA++  ++++ ++++ +d
  EEA19625.1 309 ALLNLAILHADFGSYTEALSAMQEAISIARESHD 342
                 89******************99998887777665 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 3.2
       TPR_7  11 rlGdyeeAielye 23 
                 r G++++Ai + e
  EEA19625.1 570 RKGHHSQAIAIVE 582
                 7899999998765 PP

  == domain 3  score: 1.9 bits;  conditional E-value: 0.13
       TPR_7   4 nLarlysrlGdyeeAielye 23 
                  La +  +++++e A+e  e
  EEA19625.1 644 VLATVLLSMREFEAAVEMME 663
                 5899999*********9877 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.4   0.00011      0.25       5      62 ..     275     335 ..     273     341 .. 0.85
   2 ?   -2.8   0.0       4.9   1.1e+04       3      20 ..     645     662 ..     645     664 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00011
      TPR_16   5 raalragdyddAaaaleaalkrdpssPd...aaeAllllgdaalrqgrlaeAaalyraalr 62 
                 ++a++agdy+     l+++ ++   s d      All+l+ +++ +g ++eA+ + ++a+ 
  EEA19625.1 275 LDAWKAGDYPSSFDNLHRYFDYTVHSRDrsfYQYALLNLAILHADFGSYTEALSAMQEAIS 335
                 5788999999999999999998865555888999*******************99999974 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 4.9
      TPR_16   3 laraalragdyddAaaal 20 
                 la+ +l  +++++A+++ 
  EEA19625.1 645 LATVLLSMREFEAAVEMM 662
                 688999999999999875 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.1   8.4e-05      0.19       2      32 ..     308     338 ..     307     340 .. 0.92
   2 ?   -2.4   0.0       3.4   7.5e+03       7      22 ..     645     660 ..     640     663 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 8.4e-05
       TPR_2   2 ealynlGlayyklgdyeeAleafekAleldP 32 
                 +al nl+ +++  g y eAl a+++A++++ 
  EEA19625.1 308 YALLNLAILHADFGSYTEALSAMQEAISIAR 338
                 5899***********************9976 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 3.4
       TPR_2   7 lGlayyklgdyeeAle 22 
                 l+ +++ + ++e A+e
  EEA19625.1 645 LATVLLSMREFEAAVE 660
                 6778888899999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (789 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       490  (0.02733); expected 358.6 (0.02)
Passed bias filter:                      448  (0.0249875); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.70u 0.30s 00:00:01.00 Elapsed: 00:00:00.48
# Mc/sec: 4963.58
//
Query:       EEA19626.1  [L=302]
Description: phosphoribosyl-aminoimidazole-succinocarboxamide synthase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      6e-98  327.5   0.0    7.1e-98  327.2   0.0    1.0  1  SAICAR_synt  SAICAR synthetase


Domain annotation for each model (and alignments):
>> SAICAR_synt  SAICAR synthetase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  327.2   0.0    4e-102   7.1e-98       2     251 ..      17     277 ..      16     278 .. 0.95

  Alignments for each domain:
  == domain 1  score: 327.2 bits;  conditional E-value: 4e-102
                  EEE-SSEEEEE-SSTTEEEEEEESEEEECCCTEEEEETTHHHHHHHHHHHHHHHHH.H...--BSEEEE..............-SSSEEEEE-EEEES CS
  SAICAR_synt   2 lyeGKvrdvYeledddklllvakDrisAfdvvlkeeipgKGkvltqlsafwfekle.k...ipnhliksld..pe.......qlegrsmlvkklkmlp 86 
                  +++GKvrd+Ye+ dd++ll++a+DrisA+dv+++++ip+KGk+lt  ++ wf+ l+ k   +++hli +ld  p+       +l++rsm v+k ++++
   EEA19626.1  17 IARGKVRDLYEI-DDKTLLFIATDRISAYDVIMENGIPNKGKLLTLCTKAWFQILQdKipgLRTHLI-TLDlpPQvpesqraALQNRSMQVRKYEIFK 112
                  799*********.888****************************************73456788***.778873355688999*************** PP

                  EEEEEEEE--HHH.......HH....HH..T--TT-EEEE.EEEEEEE--CCCT.S-EE-HHHHH.HTT-HHHHHHHHHHHHHHHHHHHHHHHHTTEE CS
  SAICAR_synt  87 vEvvvRgyltGslwkeykksgkvcgirlpeglkegeklpe.piftpstKaeegehDeniseeevvealgteeeaeeieelalavyekaaelaaergii 183
                  +E++vRgy+tGs+wkey++sg+v+gi++ +glke++ +p  pi+tpstKae g+hDeni+ ++++e++g ++ a +i++lal++y+ a+++a erg+i
   EEA19626.1 113 IEAIVRGYITGSAWKEYQTSGTVHGIKIAPGLKESQAFPDgPIYTPSTKAELGAHDENIHPDQAAEIVG-AKYAPKIAKLALELYKVAHDYAYERGLI 209
                  **************************************988****************************.99************************** PP

                  EEEEEEEEEEETTTTEEEEES--.STTTEEEEETTT.....GGGB-STHHHHTT-STHHHHHHHHHHH CS
  SAICAR_synt 184 lvDtKlEFGldeedgelvLaDevltpDssRfwdaetyeegkeqeslDKqfvRdwleeveekwkekler 251
                  ++DtK+EFGld++++e+vL+DevltpDssRfw++++y  g+ q+s+DKq++Rdwl+++  k ke +++
   EEA19626.1 210 IADTKFEFGLDRSTDEIVLVDEVLTPDSSRFWPKDRYVIGQGQDSFDKQYLRDWLTSQGLKGKEGVKM 277
                  **********************************************************9999998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (302 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       394  (0.0219756); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.66u 0.34s 00:00:01.00 Elapsed: 00:00:00.57
# Mc/sec: 1582.60
//
Query:       EEA19627.1  [L=459]
Description: hexaprenyl pyrophosphate synthetase Coq1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.1e-72  241.4   0.0    2.4e-71  239.8   0.0    1.7  1  polyprenyl_synt  Polyprenyl synthetase
     0.0026   17.4   0.0     0.0042   16.7   0.0    1.2  1  HEPPP_synt_1     Heptaprenyl diphosphate synthase (HEPPP synt


Domain annotation for each model (and alignments):
>> polyprenyl_synt  Polyprenyl synthetase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  239.8   0.0   2.7e-75   2.4e-71       2     255 ..     107     410 ..     106     411 .. 0.92

  Alignments for each domain:
  == domain 1  score: 239.8 bits;  conditional E-value: 2.7e-75
                      HHHHHHHHHHHHSSS--HHHHHHHHHHHHHS.CG.......H.............................................HHHHHHH CS
  polyprenyl_synt   2 elleealeylveagGKrlRpllvllaaealk.ee.......e.............................................eelekaa 42 
                      ++l+++++y++ ++GK++Rpllvll+++a++  +       +                                             + l  ++
       EEA19627.1 107 PMLDKVAKYYTWSEGKHVRPLLVLLMSQATAlAPhnphthsSsissqqqsyisepissplvlsdanpdtspltapaadlegifgedpNILPAQR 200
                      57999**************************733455665505556667777888888899999999999999999999999999998899*** PP

                      HHHHHHHHHHHHHHHHHHHHTT-SEETTEE-HHHCTCHHHHHHHHHHHHHHHHHHHHHHHSTTHHHHHHHHHHHHHHHHHHHHHH....HHTTT CS
  polyprenyl_synt  43 vlawivellhaasLvhDDimDdsetRRGqpcahrlvGnklAindgdfllarafellaklfekslellelfsevllqtveGqlldl....eeekd 132
                      +la+i+el+h+asL+hDD++D++ tRR   +a+ ++Gnk+A+++gdfll+ra+  la+l  +++e++el+++v++++veG++++l    ++e++
       EEA19627.1 201 RLAEITELIHTASLLHDDVIDNAVTRRSSNSANTQFGNKMAVLAGDFLLGRASVALARL--RNPEVIELLATVIANLVEGEFMQLkntaSDERS 292
                      ***********************************************************..************************544433356 PP

                      TTCCC.SHHHHHHHHHHHTHHHCHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS-HHHHSS-TSHHHHTT---HHHHHHHHC CS
  polyprenyl_synt 133 ddlskfsleeyleivkyKTaylfalpvalaallagasdeelealkdiglelGlaFQiqDDylDlfgdpevlgKpagtDiqegkctlpilkalel 226
                      + +++ +++ yl++++ KTa+l++ ++++ all++ ++e +ea++++g++lGlaFQ++DD+lD++ ++ ++gKpag+D++ g +t+p+l+a++ 
       EEA19627.1 293 PVFTDDTIAYYLQKTYLKTASLISKSCRATALLGNSTPEIVEAAYSYGRNLGLAFQLVDDMLDYTVNSVEFGKPAGADLELGLATAPLLFAWK- 385
                      6677999*****************************99*******************************************************. PP

                      T-HHHHHHHHHHTTSSHHHHHHHHHHHHH CS
  polyprenyl_synt 227 aspeqrkvlkeilgkkaekeedvkealel 255
                      ++pe    l +++g+k+e+e+dv++a el
       EEA19627.1 386 SNPE----LGALVGRKFEQEGDVERAREL 410
                      8888....****************99886 PP

>> HEPPP_synt_1  Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   4.7e-07    0.0042      41     109 ..     205     278 ..     188     293 .. 0.77

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 4.7e-07
  HEPPP_synt_1  41 tamlvqiAldtHdkvsek.keeeeeekknrq....LtVLAGdyYSglYYklLaevkdielirllaeaikeineh 109
                    + l+++A   Hd v ++  +++ +++ n q    + VLAGd+  g    +La++++ e i+lla+ i +  e 
    EEA19627.1 205 ITELIHTASLLHDDVIDNaVTRRSSNSANTQfgnkMAVLAGDFLLGRASVALARLRNPEVIELLATVIANLVEG 278
                   4568999999999876554555555555555333389*****************************99988775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (459 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       406  (0.0226449); expected 358.6 (0.02)
Passed bias filter:                      353  (0.0196888); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.70u 0.35s 00:00:01.04 Elapsed: 00:00:00.57
# Mc/sec: 2438.94
//
Query:       EEA19628.1  [L=646]
Description: proteasome regulatory particle subunit (RpnC), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.2e-25   87.6   0.9    5.2e-25   87.6   0.9    2.1  2  Rpn3_C           Proteasome regulatory subunit C-terminal
    9.8e-19   67.8   0.1      8e-18   64.9   0.0    2.5  3  PCI              PCI domain
  ------ inclusion threshold ------
       0.04   14.0   0.0       0.15   12.3   0.0    2.1  1  TPR_2            Tetratricopeptide repeat
      0.064   13.2   0.2       0.76    9.8   0.1    2.6  2  CSN8_PSD8_EIF3K  CSN8/PSMD8/EIF3K family
          6    5.3   6.3        9.4    4.6   6.3    1.3  1  Macoilin         Macoilin family


Domain annotation for each model (and alignments):
>> Rpn3_C  Proteasome regulatory subunit C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.5         5   1.8e+04      51      63 ..     140     152 ..     135     159 .. 0.46
   2 !   87.6   0.9   1.5e-28   5.2e-25       1      66 [.     572     635 ..     572     638 .. 0.97

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 5
      Rpn3_C  51 qqeeelakelede 63 
                 ++e+++a e +de
  EEA19628.1 140 KKEDDVAMEGSDE 152
                 2344444444442 PP

  == domain 2  score: 87.6 bits;  conditional E-value: 1.5e-28
      Rpn3_C   1 DvYsTkePqeaFdeRIkFclqlHneavkAMRYpedakkkelesaeearerqqeeelakelededld 66 
                 D+Y T+eP eaF+ RI+ cl+lH+e+vkAMR+p+++++ el++a+earer  e+el ke++d+d+d
  EEA19628.1 572 DIYLTTEPGEAFHARIQACLSLHDESVKAMRFPMNQHRLELKNAQEARER--ERELVKEIQDGDMD 635
                 9*************************************************..**********8887 PP

>> PCI  PCI domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0      0.69   2.5e+03      35      69 ..     178     212 ..     162     231 .. 0.81
   2 ?   -2.6   0.0       2.1   7.7e+03      57      69 ..     310     322 ..     269     371 .. 0.60
   3 !   64.9   0.0   2.2e-21     8e-18       3     102 ..     467     566 ..     465     569 .. 0.96

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.69
                 HHHHHHHHHHHHHHHHHHHHHHCESEEEHHHHHHH CS
         PCI  35 laqllesLekkvrerllrqvskiyssislerlakl 69 
                 l+  ++ +  + ++r+lr++s   + i+ + la+ 
  EEA19628.1 178 LERAVTHFDARFTLRVLRSISSMRKHITPDVLAEV 212
                 44567788889999999999999999999999875 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 2.1
                 CESEEEHHHHHHH CS
         PCI  57 iyssislerlakl 69 
                 +y s+ +e+la l
  EEA19628.1 310 FYFSLFYEQLAPL 322
                 2333444444433 PP

  == domain 3  score: 64.9 bits;  conditional E-value: 2.2e-21
                 HHHHHHHHHHTSHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHCESEEEHHHHHHHHTSSH.HHHHHHHHHHHHTTSSSEEEETTTTE CS
         PCI   3 ysdllkalrsgnlsgfseelkdleeelladdglaqllesLekkvrerllrqvskiyssislerlaklldlsv.devEkilvklIrdgeirakidqesgi 100
                 y  l++a+ +g+l+gf  +++ +    +++dg+++l+ +L+++v+++ +r +s  ys+isl ++   l+l + + +E+i++k+Irdg i+a++d+e+g+
  EEA19628.1 467 YFLLVRAVSTGDLDGFLNIVNTH-GATFRKDGTYTLILRLRQNVIKTGIRVMSIAYSRISLRDICLRLGLHSeESAEYIVAKAIRDGVIDATLDHEQGY 564
                 7779*******************.9*********************************************99899***********************9 PP

                 EE CS
         PCI 101 vv 102
                 + 
  EEA19628.1 565 MK 566
                 86 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   4.2e-05      0.15       1      33 [.     392     424 ..     392     425 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 4.2e-05
       TPR_2   1 aealynlGlayyklgdyeeAleafekAleldPn 33 
                 a++ly+lG++ + + +y eA+e++  A +  P+
  EEA19628.1 392 ARYLYYLGRIRAIQLRYSEAHEHLTGATRKSPT 424
                 789*********************999998887 PP

>> CSN8_PSD8_EIF3K  CSN8/PSMD8/EIF3K family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0      0.27   9.8e+02      72     106 ..     178     212 ..     172     227 .. 0.88
   2 ?    9.8   0.1   0.00021      0.76      46     122 ..     469     547 ..     351     556 .. 0.72

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.27
  CSN8_PSD8_EIF3K  72 ltadvagleelvReeiaklvgkaYesIsadvlael 106
                      l  +v+ +   +  ++++++++  + I++dvlae 
       EEA19628.1 178 LERAVTHFDARFTLRVLRSISSMRKHITPDVLAEV 212
                      5678999999**********************986 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00021
  CSN8_PSD8_EIF3K  46 tLetlLeeanyakfwstlksddlsa...dltadvagleelvReeiaklvgkaYesIsadvlaelLglssdeelekfvkev 122
                       L +++++++   f ++++ +            +  l+++v +  +++++ aY+ Is  ++   Lgl  +ee +++++++
       EEA19628.1 469 LLVRAVSTGDLDGFLNIVNTHGATFrkdGTYTLILRLRQNVIKTGIRVMSIAYSRISLRDICLRLGLH-SEESAEYIVAK 547
                      56666666666666666665532211112334456677788888899*********************.99999988876 PP

>> Macoilin  Macoilin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   6.3    0.0026       9.4     300     387 ..       9      91 ..       2     184 .. 0.64

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.0026
    Macoilin 300 ksessgsesellveesvkskssssssssnknskkasagsagssnssskkhsessksvtsssssknskkqklpaGkssaalkdaaensl 387
                 +s+s+g++s+ +  e+++++s+++ss++  +   ++ ++a+ ++s+++k+  + k  +ss++++n+    +++ + +++  d++en +
  EEA19628.1   9 RSNSKGDTSSSTNGEKSRANSNTASSKD--KAAPTTRSAANKAKSAPAKKAVTGKGASSSNTANNN---TMSGDQPQRNGTDPVENGV 91 
                 3344444444444444444444444432..233334445677778888877777777777665553...2333345556666666644 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (646 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1178  (0.0657036); expected 358.6 (0.02)
Passed bias filter:                      682  (0.0380389); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.87u 0.41s 00:00:01.28 Elapsed: 00:00:00.58
# Mc/sec: 3336.98
//
Query:       EEA19629.1  [L=242]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.5e-43  146.8   9.8    1.1e-22   81.0   0.2    2.0  2  DASH_Spc34      DASH complex subunit Spc34
  ------ inclusion threshold ------
      0.018   14.9   0.3      0.035   13.9   0.3    1.4  1  DUF724          Protein of unknown function (DUF724)
       0.35   11.8   6.6      0.089   13.7   2.7    1.9  2  PRKG1_interact  cGMP-dependent protein kinase interacting dom
        1.2    9.1   7.6       0.13   12.2   3.1    1.6  2  DASH_Spc19      Spc19


Domain annotation for each model (and alignments):
>> DASH_Spc34  DASH complex subunit Spc34
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.0   0.2   2.5e-26   1.1e-22       1      93 [.       4      97 ..       4     102 .. 0.84
   2 !   69.8   6.6     7e-23   3.1e-19     136     253 ..      81     224 ..      75     226 .. 0.88

  Alignments for each domain:
  == domain 1  score: 81.0 bits;  conditional E-value: 2.5e-26
  DASH_Spc34  1 LdscLeeikqSveSisslkFkpPgIFtNAlvkkddItkLirDtepeeeaLfkidkvekkpeRkDGkkg.vlDylteretnlkrnrrlglpekkp 93
                L+s+Le+i+ S+++i++l F+pP+IFtNAl++++dIt LirDte +e+aLf++d   k ++R+  ++g  ++  t+ret + r +  +++ +++
  EEA19629.1  4 LESHLEQITLSANAIADLSFPPPKIFTNALLNTPDITALIRDTEVHERALFTLDASAKPSQRRATRRGtTFPADTQRETMISRINAARSNRHQS 97
                899****************************************************877777777766515688888888887777666655555 PP

  == domain 2  score: 69.8 bits;  conditional E-value: 7e-23
  DASH_Spc34 136 dsgssseka...nrrktafve.......................dfdvelllkvleelltkyplleakekieelreeYeelseeieeleaeiaeQkkqL 208
                 ++++s+ +a   nr ++a++                        +++ve+llk++e l+++yp+++a eki  lr +Y+++se++  lea++a+ +++L
  EEA19629.1  81 ETMISRINAarsNRHQSAVARvlgndmmeeirrsagsstrlqrgEVNVEVLLKGAEILCNVYPVAGAAEKIADLRYRYSQISESLVRLEARVADNTAEL 179
                 45555555555455555555588888888888888889999999******************************************************* PP

  DASH_Spc34 209 eaqnknesessseddsesetskskdvdelirkEeeeIeeLerklk 253
                 e++n+ ++ +++ + +e ++++++++d++i++E +eI++Ler+++
  EEA19629.1 180 ERMNEAYDRDNEIEYQEPQQHDTQVTDDDIERELKEIRQLERRKQ 224
                 *********9999999999***********************986 PP

>> DUF724  Protein of unknown function (DUF724)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.3   7.9e-06     0.035      93     179 ..     147     235 ..     139     240 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 7.9e-06
      DUF724  93 rlnkLlslkdeqtklleerkklekkieeeesekrkleeeid.elekkilelerqlallk.ekkeaadkeiarlkseaekleeeledveq 179
                   +k+  l+ +++++ e + +le +++++++e ++++e  d ++e + +e +++++++   + e++ kei +l+  ++ le+++  + +
  EEA19629.1 147 AAEKIADLRYRYSQISESLVRLEARVADNTAELERMNEAYDrDNEIEYQEPQQHDTQVTdDDIERELKEIRQLERRKQVLEDRVTGMSR 235
                 56789999***************************99987644555666777776666678899999*************999988766 PP

>> PRKG1_interact  cGMP-dependent protein kinase interacting domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.1      0.79   3.6e+03      30      37 ..      85      92 ..      50     127 .. 0.57
   2 ?   13.7   2.7     2e-05     0.089      15      88 ..     153     228 ..     146     239 .. 0.70

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.79
  PRKG1_interact 30 lkselekl 37
                    ++ + +++
      EEA19629.1 85 SRINAARS 92
                    22222222 PP

  == domain 2  score: 13.7 bits;  conditional E-value: 2e-05
  PRKG1_interact  15 rLkreLeelekelselkseleklkqqrqesvskrssllelekrerrslerkis..eleeelkeleeLraenqrLkd 88 
                      L+ + ++++++l +l+++++  + + ++ +++  +  e+e +e ++ + +++  ++e elke+++L + +q L d
      EEA19629.1 153 DLRYRYSQISESLVRLEARVADNTAELERMNEAYDRDNEIEYQEPQQHDTQVTddDIERELKEIRQLERRKQVLED 228
                     566666677777777777777666553333334445566677777777777765589**************99987 PP

>> DASH_Spc19  Spc19
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.1       0.6   2.7e+03     108     122 ..      78      92 ..      43     124 .. 0.48
   2 ?   12.2   3.1   2.8e-05      0.13      75     154 ..     150     230 ..     144     233 .. 0.57

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.6
                 HHT-XXXXXXXXXXX CS
  DASH_Spc19 108 eeseeskeeeeeeen 122
                 +++e++ ++ + +++
  EEA19629.1  78 TQRETMISRINAARS 92 
                 333333332222222 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 2.8e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHH......HHHHT-XXXXXXXXXX.XX....XXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  DASH_Spc19  75 eleklerreetLkaklelqegrlsnaesskkeeeeseeskeeeeeee.nkeeekskkkltkeelerlkkLkqkKerLkytl 154
                 +++ l+ r +++ + l  +e r+ +++++ ++ +e+ ++++e e +e ++++ + +++  ++el+++++L ++K+ L+ ++
  EEA19629.1 150 KIADLRYRYSQISESLVRLEARVADNTAELERMNEAYDRDNEIEYQEpQQHDTQVTDDDIERELKEIRQLERRKQVLEDRV 230
                 5555666666666666666666655544444433333333333333303333333333667899*************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (242 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1134  (0.0632495); expected 358.6 (0.02)
Passed bias filter:                      524  (0.0292264); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.65u 0.34s 00:00:00.99 Elapsed: 00:00:00.55
# Mc/sec: 1313.77
//
Query:       EEA19630.1  [L=668]
Description: transcription initiation factor TFIID subunit 12, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.3e-21   74.9   0.0    8.4e-21   74.2   0.0    1.3  1  TFIID_20kDa    Transcription initiation factor TFIID subunit 
  ------ inclusion threshold ------
        1.4    7.7  18.5        3.9    6.2  18.5    1.7  1  MDM10          Mitochondrial distribution and morphology prot


Domain annotation for each model (and alignments):
>> TFIID_20kDa  Transcription initiation factor TFIID subunit A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.2   0.0   9.4e-25   8.4e-21       1      68 []     558     628 ..     558     628 .. 0.95

  Alignments for each domain:
  == domain 1  score: 74.2 bits;  conditional E-value: 9.4e-25
                  -HHHHHHHHHCC...-SS----HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-SEE-HHHHHHHHHHHS-- CS
  TFIID_20kDa   1 sKrklqdLvqqv...dsetkldedvedlLleiaddFvesvtkfacklakhRksdklevrDiqlhlernynm 68 
                  sK+ l+ Lv+qv      + l +d e+ +l++addFv++v+++ac+lak R s++le rDiql lernynm
   EEA19630.1 558 SKKMLDILVRQVtggGEGEGLTPDAEEFILQMADDFVDDVITAACRLAKLRPSSTLEIRDIQLVLERNYNM 628
                  7999999*****77656789**************************************************9 PP

>> MDM10  Mitochondrial distribution and morphology protein 10
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2  18.5   0.00043       3.9     306     400 ..      77     175 ..      73     203 .. 0.51

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.00043
       MDM10 306 nlslGmeLwrksrkkksseeeeeeeekekeeesvkskkeakkkkkekekeeekstfssslekadkeksveesfqakleWrldkeekeeek......kke 398
                 nl+ Gm+L+r++ +++++++++++++++++ +++++++++++++++++ +++++++++ + +a+++ +++++ qa+ + + +++++++ +      +  
  EEA19630.1  77 NLMKGMQLFRTKLQQQQQQQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQQQAQQQGQiqpvqqQ-- 173
                 7889********9988888777666665555444444333333333333333332222222222223333333333332222222222223343321.. PP

       MDM10 399 kk 400
                 ++
  EEA19630.1 174 QQ 175
                 22 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (668 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      4627  (0.258074); expected 358.6 (0.02)
Passed bias filter:                      974  (0.0543254); expected 358.6 (0.02)
Passed Vit filter:                       494  (0.0275531); expected 17.9 (0.001)
Passed Fwd filter:                       157  (0.00875676); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 2.82u 0.49s 00:00:03.30 Elapsed: 00:00:00.78
# Mc/sec: 2589.11
//
Query:       EEA19631.1  [L=986]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.3e-13   48.5   0.1    1.3e-12   47.7   0.1    1.3  1  CorA      CorA-like Mg2+ transporter protein


Domain annotation for each model (and alignments):
>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.7   0.1   7.2e-17   1.3e-12     109     290 ..     415     602 ..     402     612 .. 0.69

  Alignments for each domain:
  == domain 1  score: 47.7 bits;  conditional E-value: 7.2e-17
        CorA 109 gellyrlldeivdrlfellekleeeldeledel....edstkkeilrelaq..lr.rrlvkl.rralapnrevlkrlla..kaddkllddedkeylrdl 197
                 + +l  ++ ++v   ++ l++  +++  le  +    +d++++++l e +   l+ ++lv++  +++ ++++ l++l +   ++d++l+d     +++l
  EEA19631.1 415 KAILSDIFKAVVMAWDAFLDHAVTHMTILEGKIyerpDDESRAPELWENSSawLKvEKLVNVhASVMQQMKTRLHELTDdvDTEDNWLEDSP-SDFERL 512
                 56888899999999999999999999999999997776666666666666623444445555233344444455555556544444444443.345555 PP

        CorA 198 ldeler.llemlealrerleslqdtyssllserlNrvmkvLTvltaiflPlTlitGiyGmNfkglPelewsygypfvlllglmallailllfwf 290
                  + ++  l + +e+l ++l +  ++  s+ s +l   m +L+ +t iflPlT+i+G++GmN++    ++ s     +++++++  ++++l+f+f
  EEA19631.1 513 TNLITEdLTKPTESLISLLYQSVSIRDSRHSLELGVSMWRLSWITFIFLPLTFIVGFFGMNVDT-FSNNPSIK---WYFIAAIPFMFGVLTFYF 602
                 555555788888888889999999999999999******************************4.43333332...333444444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (986 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       763  (0.0425568); expected 358.6 (0.02)
Passed bias filter:                      496  (0.0276647); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.80u 0.32s 00:00:01.12 Elapsed: 00:00:00.48
# Mc/sec: 6135.48
//
Query:       EEA19632.1  [L=687]
Description: eukaryotic translation initiation factor subunit eIF2A, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.8e-81  270.8   0.0      5e-80  268.0   0.0    2.1  2  eIF2A         Eukaryotic translation initiation factor eIF2A
    0.00074   20.3   0.6       0.12   13.3   0.1    4.1  4  WD40          WD domain, G-beta repeat
  ------ inclusion threshold ------
      0.021   15.1   0.0         29    5.0   0.0    4.7  6  ANAPC4_WD40   Anaphase-promoting complex subunit 4 WD40 domai
      0.025   13.1   0.0      0.048   12.2   0.0    1.4  1  Cytochrom_D1  Cytochrome D1 heme domain
       0.08   12.9   0.6         42    4.2   0.1    4.4  5  PD40          WD40-like Beta Propeller Repeat
      0.096   10.7   0.0       0.18    9.8   0.0    1.3  1  IKI3          IKI3 family


Domain annotation for each model (and alignments):
>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.0      0.21   6.2e+02     129     160 ..      59      90 ..      34     116 .. 0.65
   2 !  268.0   0.0   1.7e-83     5e-80       1     194 []     219     413 ..     219     413 .. 0.99

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.21
                 EEETTTTEEEEEEE-TT--EEEE-TTSSEEEE CS
       eIF2A 129 iwdvkkkkkiakaeaanatlvewspdgryvlT 160
                 i d +  + i+++ a n   + +sp g+yv+T
  EEA19632.1  59 IIDPSVGHVITTLPADNVFELGFSPLGTYVIT 90 
                 34444444555555555556666666666666 PP

  == domain 2  score: 268.0 bits;  conditional E-value: 1.7e-83
                 EEESSECEEEEEE-TTTTEEEEEEE.E--TT-CEEEEEEEEEESSSTT--EEECCEESSS.EEEEEE-TTSS-EEEEESSSSCEEEEEECSCEEEEEEE CS
       eIF2A   1 ksffkadkvklkWnkkGtsllvlvstevdktnksyygetelyliklkkkksevvelkkegpihdvaWspkskefaviyGkmpakvslfdlkvkviskle 99 
                 k+ffk dkv+lkWn++Gts++vl++t+vd+++ksyyget+lyl+++++ ++++++l++egpihdv+Wsp+skef v+yG+mpak+++f+ ++ +++++ 
  EEA19632.1 219 KTFFKGDKVQLKWNNSGTSIIVLAQTDVDRSGKSYYGETTLYLLSATGAFDSRIDLDREGPIHDVTWSPNSKEFGVVYGFMPAKTTIFNFRGVATHSYP 317
                 89************************************************************************************************* PP

                 EES--EEEE-TTSSEEEEE-TTSSS-EEEEEETT.TTEEEEEEE-TT--EEEE-TTSSEEEEEE-TTT-SSS-EEEEEETTTEEEEEEE-TTEEEE CS
       eIF2A 100 eqkrNtiffspkgklvllaGfgnlaGeleiwdvk.kkkkiakaeaanatlvewspdgryvlTattaprlrvdngfkiwsysGklvykkefdelyqv 194
                  ++rNti+fsp+g++v++aGfgnlaG+++i+d +   +ki+++e +nat++ewspdg+++lTatt+prlrvdng++iw+++G+l y+++++elyqv
  EEA19632.1 318 LAPRNTIVFSPHGRFVVVAGFGNLAGQMDIYDLEkGHQKITTIEGSNATVCEWSPDGKHILTATTSPRLRVDNGVRIWHVTGALQYNEDMNELYQV 413
                 ********************************997899********************************************************98 PP

>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       4.4   1.3e+04      14      26 ..      69      89 ..      62     102 .. 0.66
   2 ?   -0.1   0.0      0.66     2e+03      12      23 ..     279     290 ..     265     293 .. 0.86
   3 ?    0.8   0.0      0.34     1e+03      15      28 ..     323     337 ..     308     341 .. 0.77
   4 !   13.3   0.1     4e-05      0.12       8      37 ..     352     395 ..     344     396 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 4.4
                EEEE........EETTSSEEE CS
        WD40 14 tsla........fspdgawla 26
                t l         fsp g++++
  EEA19632.1 69 TTLPadnvfelgFSPLGTYVI 89
                444333333333899888876 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.66
                 SEEEEEEETTSS CS
        WD40  12 svtslafspdga 23 
                 +++++ +sp+++
  EEA19632.1 279 PIHDVTWSPNSK 290
                 499******986 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.34
                 EEEEETTSSEEE.EE CS
        WD40  15 slafspdgawla.sG 28 
                  + fsp+g++++ +G
  EEA19632.1 323 TIVFSPHGRFVVvAG 337
                 566*******87244 PP

  == domain 4  score: 13.3 bits;  conditional E-value: 4e-05
                 ESSSSEEEEE........EETTSSEEEEEET......TSEEEEE CS
        WD40   8 tGHssvtsla........fspdgawlasGsd......DgtvriW 37 
                 +GH+ +t +         +spdg+ +++++       D+ vriW
  EEA19632.1 352 KGHQKITTIEgsnatvceWSPDGKHILTATTsprlrvDNGVRIW 395
                 599779988888899999********98853344556******* PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.0      0.29   8.7e+02      39      80 ..      35      75 ..      27      94 .. 0.80
   2 ?   -0.8   0.0      0.63   1.9e+03      43      58 ..     228     243 ..     216     264 .. 0.79
   3 ?   -2.3   0.0       1.9   5.6e+03      37      57 ..     276     296 ..     270     297 .. 0.80
   4 ?    1.2   0.0      0.15   4.6e+02      44      89 ..     324     370 ..     321     373 .. 0.67
   5 ?    1.9   0.0     0.091   2.7e+02      30      61 ..     358     385 ..     352     391 .. 0.77
   6 ?    5.0   0.0    0.0097        29      13      52 ..     380     421 ..     368     421 .. 0.74

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.29
  ANAPC4_WD40 39 sevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvks 80
                 ++ r+ a++p g+ +a a    +v ++d + g+v+ +l++++
   EEA19632.1 35 GNLRCSAYSPCGRYFAWAS-PERVTIIDPSVGHVITTLPADN 75
                 5667778999999999885.5699**********99998865 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.63
  ANAPC4_WD40  43 sLaWkpdgklLavays 58 
                  +L+W+++g+ + v  +
   EEA19632.1 228 QLKWNNSGTSIIVLAQ 243
                  69******99888765 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 1.9
  ANAPC4_WD40  37 edsevrsLaWkpdgklLavay 57 
                  +++ ++++ W+p+ k + v+y
   EEA19632.1 276 REGPIHDVTWSPNSKEFGVVY 296
                  567899999***999877765 PP

  == domain 4  score: 1.2 bits;  conditional E-value: 0.15
  ANAPC4_WD40  44 LaWkpdgklLavay...sdgevrlldaesgkvvhslsvksekavtclgW 89 
                  + ++p g++ +va      g++ ++d e+g+   +   +s+   t  +W
   EEA19632.1 324 IVFSPHGRFVVVAGfgnLAGQMDIYDLEKGHQKITTIEGSN--ATVCEW 370
                  67899999999875111468999999999986555444444..455555 PP

  == domain 5  score: 1.9 bits;  conditional E-value: 0.091
  ANAPC4_WD40  30 wtleedkedsevrsLaWkpdgklLavaysdge 61 
                   t+    e+s+ +  +W+pdgk +  a+   +
   EEA19632.1 358 TTI----EGSNATVCEWSPDGKHILTATTSPR 385
                  444....788889999******9998887655 PP

  == domain 6  score: 5.0 bits;  conditional E-value: 0.0097
  ANAPC4_WD40  13 atedgellvfRlngqrvwtl....eedkedsevrsLaWkpdgkl 52 
                  at++ +l+v   ng r+w++    + +++ +e  +++W+p+g++
   EEA19632.1 380 ATTSPRLRVD--NGVRIWHVtgalQYNEDMNELYQVCWRPQGQV 421
                  5555555443..999***999998788888999********986 PP

>> Cytochrom_D1  Cytochrome D1 heme domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   1.6e-05     0.048      41      98 ..     324     384 ..     311     388 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 1.6e-05
                   EE-TT.SSEEEEEETT...SEEEEEESSSSSEEEEEE-SSEEEEEEE--TTSEEEEEEEET CS
  Cytochrom_D1  41 rvfasdgRyvyvigRD...gkvtliDLwakeivaevkiGlnarsvavSqddryvivgnYlP 98 
                    vf++ gR+v v+g     g+++++DL + +   + + G+na   + S d++++++++  P
    EEA19632.1 324 IVFSPHGRFVVVAGFGnlaGQMDIYDLEKGHQKITTIEGSNATVCEWSPDGKHILTATTSP 384
                   68***********9752227778888877778888889****************9987666 PP

>> PD40  WD40-like Beta Propeller Repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0      0.38   1.1e+03      12      27 ..      38      53 ..      33      53 .. 0.83
   2 ?   -3.1   0.0       2.8   8.4e+03      24      34 ..     192     201 ..     191     202 .. 0.87
   3 ?    0.6   0.0      0.19   5.8e+02       8      21 ..     277     290 ..     274     290 .. 0.83
   4 ?    1.0   0.0      0.15   4.4e+02      14      37 ..     324     348 ..     322     348 .. 0.92
   5 ?    4.2   0.1     0.014        42      16      23 ..     370     377 ..     370     378 .. 0.90

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.38
                EEEEE-TTSSEEEEEE CS
        PD40 12 gaPsfSPDGkrlaFsS 27
                 + ++SP G+++a++S
  EEA19632.1 38 RCSAYSPCGRYFAWAS 53
                57789999******98 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 2.8
                 EEEEECT.TCE CS
        PD40  24 aFsSdRgsGkp 34 
                 +F+ +R+ G+p
  EEA19632.1 192 VFTPERK-GQP 201
                 89****9.987 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.19
                 SS.EEEEEE-TTSS CS
        PD40   8 pgnegaPsfSPDGk 21 
                 +g++++ ++SP+ k
  EEA19632.1 277 EGPIHDVTWSPNSK 290
                 5889999****965 PP

  == domain 4  score: 1.0 bits;  conditional E-value: 0.15
                 EEE-TTSSEEEEEEECT..TCEEEE CS
        PD40  14 PsfSPDGkrlaFsSdRg.sGkpdIy 37 
                 + fSP G+  + + +++  G+ dIy
  EEA19632.1 324 IVFSPHGRFVVVAGFGNlAGQMDIY 348
                 689************99*******9 PP

  == domain 5  score: 4.2 bits;  conditional E-value: 0.014
                 E-TTSSEE CS
        PD40  16 fSPDGkrl 23 
                 +SPDGk +
  EEA19632.1 370 WSPDGKHI 377
                 ******87 PP

>> IKI3  IKI3 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0   5.9e-05      0.18     205     268 ..     357     420 ..     342     422 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 5.9e-05
                 XX.XXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        IKI3 205 ls.lddskvtIs.WRGDgeYfavssleaetgerralrvyeregaLdsvsekvdgleeaLaWrPsGs 268
                 ++  + s++t++ W  Dg+ + + ++++       +r++  +gaL++ +e+++ l  +++WrP+G+
  EEA19632.1 357 ITtIEGSNATVCeWSPDGKHILTATTSPRLRVDNGVRIWHVTGALQY-NEDMNELY-QVCWRPQGQ 420
                 4445555556555****************999*************97.56666664.69******7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (687 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       888  (0.0495287); expected 358.6 (0.02)
Passed bias filter:                      434  (0.0242066); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.67u 0.28s 00:00:00.95 Elapsed: 00:00:00.43
# Mc/sec: 4758.99
//
Query:       EEA19633.1  [L=342]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       426  (0.0237604); expected 358.6 (0.02)
Passed bias filter:                      185  (0.0103185); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.51
# Mc/sec: 2032.57
//
Query:       EEA19634.1  [L=543]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (543 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       636  (0.0354733); expected 358.6 (0.02)
Passed bias filter:                      222  (0.0123822); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.65u 0.33s 00:00:00.98 Elapsed: 00:00:00.47
# Mc/sec: 3438.47
//
Query:       EEA19635.1  [L=424]
Description: sister chromatid cohesion acetyltransferase Eco1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-26   92.0   0.0      3e-25   88.0   0.0    2.4  2  Acetyltransf_13  ESCO1/2 acetyl-transferase
    3.9e-13   49.0   0.1    8.1e-13   48.0   0.1    1.6  1  zf-C2H2_3        zinc-finger of acetyl-transferase ESCO


Domain annotation for each model (and alignments):
>> Acetyltransf_13  ESCO1/2 acetyl-transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0     0.039   3.5e+02      33      63 ..      54      84 ..      32      87 .. 0.77
   2 !   88.0   0.0   3.3e-29     3e-25       2      69 .]     349     417 ..     348     417 .. 0.98

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.039
  Acetyltransf_13 33 fiyglelekeevAFsqPTesGkklarkyfgt 63
                      i + ++  + v  s+P++ G   +++ +++
       EEA19635.1 54 AIRESSIAVTAVTASSPSRRGSVIFSEITQE 84
                     4457778888888999999999888887776 PP

  == domain 2  score: 88.0 bits;  conditional E-value: 3.3e-29
  Acetyltransf_13   2 palcGisriWvssshRrkgiAtkLldaarenfiyglelekeevAFsqPTesGkklarkyfgte.dflvY 69 
                      pa++G+sriW++ s+Rr+gi + Lld++++nfiygl ++ke++AF+qPT+sG +la+ +fg    ++vY
       EEA19635.1 349 PAIVGVSRIWTCGSARRRGIGMDLLDCVISNFIYGLDIPKEQIAFTQPTDSGLRLAECFFGVGePWHVY 417
                      89***********************************************************98899999 PP

>> zf-C2H2_3  zinc-finger of acetyl-transferase ESCO
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.0   0.1   9.1e-17   8.1e-13       1      39 [.     162     198 ..     162     199 .. 0.91

  Alignments for each domain:
  == domain 1  score: 48.0 bits;  conditional E-value: 9.1e-17
   zf-C2H2_3   1 QlvLdlgqksfgasqCkeCgMvYnpgspeDeklHkkfHa 39 
                 Ql++d+g +  ++  C+ CgM+Y+p+++eD+ lH+kfH+
  EEA19635.1 162 QLQIDAGITVRRS--CNLCGMEYVPSNAEDADLHDKFHS 198
                 9******776555..***********************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (424 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       644  (0.0359195); expected 358.6 (0.02)
Passed bias filter:                      484  (0.0269954); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 2692.99
//
Query:       EEA19636.1  [L=262]
Description: RNA processing protein Emg1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.3e-80  267.7   0.0    6.2e-80  267.4   0.0    1.0  1  EMG1      EMG1/NEP1 methyltransferase
  ------ inclusion threshold ------
      0.057   13.2   0.0       0.12   12.2   0.0    1.4  2  RP854     Uncharacterized protein RP854


Domain annotation for each model (and alignments):
>> EMG1  EMG1/NEP1 methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  267.4   0.0   6.9e-84   6.2e-80       1     194 []      51     256 ..      51     256 .. 0.98

  Alignments for each domain:
  == domain 1  score: 267.4 bits;  conditional E-value: 6.9e-84
                 EEEEEES--B--GG.......SCGGSB--HHHHCGG.TTSTTGGGSS-CHHHHHHHHHHHCSCHHCTT.EEEEEEETTSEEEEE-TT----SSHHHHHH CS
        EMG1   1 ivLeeasLelvkvk.......kkseqLLnsddhkkilkklkreakeaRpDIvHqcLlalldspLnkagllqvyihttknvlIevnpqtRiPrtfkrFag 92 
                 +vL +asLe+++ +       +++++LLnsd+h  +++k++r+ ++aRpDI+HqcLl+lldsp+nkagllq+yiht+k+vlIev+p++RiPrtfkrFag
  EEA19636.1  51 VVLSNASLETYRSShggrngrEEKYSLLNSDEHIGVMRKMNRDISDARPDITHQCLLTLLDSPINKAGLLQIYIHTAKGVLIEVSPTVRIPRTFKRFAG 149
                 89***********999*********************************************************************************** PP

                 HHHHHHCCSEEEETTEE.SCEEEECS-HHHHCCC.SEEEEE-TTSEE-..................EEEE-SSSS......---HHEEESSSS---HHH CS
        EMG1  93 LmvqLLkklsirategeekLlkviknpitdhlppgskiillsesaekklvdleefv.....vkpvvfvigamskgsvki..dykeeeisisnypLsaav 184
                 LmvqLL++lsir+t+++ekLlkviknpitdhlpp++++++ls++a+  +v+++e++     ++++++++gam+kg++++  ++k+e i+isny+Lsa+v
  EEA19636.1 150 LMVQLLHRLSIRSTNSQEKLLKVIKNPITDHLPPNCRKVTLSFEAP--VVRVNEYIsslgpKESICVFVGAMAKGRDDFadEFKDEAIAISNYSLSASV 246
                 **********************************************..889*****9999999************8888899***************** PP

                 HHHHHHHHCH CS
        EMG1 185 vcskiltafE 194
                 +csk+++a E
  EEA19636.1 247 ACSKFCHAAE 256
                 *******987 PP

>> RP854  Uncharacterized protein RP854
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0      0.79   7.1e+03      60      79 ..      75      94 ..      73     106 .. 0.66
   2 ?   12.2   0.0   1.3e-05      0.12      63     151 ..     163     252 ..     149     259 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 0.79
       RP854 60 ysvinskeeilesykkyvdl 79
                ys++ns e i    k   d+
  EEA19636.1 75 YSLLNSDEHIGVMRKMNRDI 94
                88888888876555554444 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 1.3e-05
       RP854  63 inskeeilesykkyvdlsvpkss.vsclnyqelipkikslrskydlvepidvsinsvffknnvqviegeneaihvnnysinikyacadfl 151
                  ns+e++l+  k+ ++  +p +     l ++  + +++   s     e i v++ ++    +  + e ++eai + nys+    ac+ f 
  EEA19636.1 163 TNSQEKLLKVIKNPITDHLPPNCrKVTLSFEAPVVRVNEYISSLGPKESICVFVGAMAKGRDDFADEFKDEAIAISNYSLSASVACSKFC 252
                 6999********999888887651567999999******999999***********999999999*********************9995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (262 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       417  (0.0232584); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.31s 00:00:00.81 Elapsed: 00:00:00.50
# Mc/sec: 1587.38
//
Query:       EEA19637.1  [L=247]
Description: RNA processing protein Emg1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.4e-80  267.9   0.0      5e-80  267.7   0.0    1.0  1  EMG1      EMG1/NEP1 methyltransferase
  ------ inclusion threshold ------
      0.049   13.4   0.0        0.1   12.4   0.0    1.4  2  RP854     Uncharacterized protein RP854


Domain annotation for each model (and alignments):
>> EMG1  EMG1/NEP1 methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  267.7   0.0   5.6e-84     5e-80       1     194 []      36     241 ..      36     241 .. 0.98

  Alignments for each domain:
  == domain 1  score: 267.7 bits;  conditional E-value: 5.6e-84
                 EEEEEES--B--GG.......SCGGSB--HHHHCGG.TTSTTGGGSS-CHHHHHHHHHHHCSCHHCTT.EEEEEEETTSEEEEE-TT----SSHHHHHH CS
        EMG1   1 ivLeeasLelvkvk.......kkseqLLnsddhkkilkklkreakeaRpDIvHqcLlalldspLnkagllqvyihttknvlIevnpqtRiPrtfkrFag 92 
                 +vL +asLe+++ +       +++++LLnsd+h  +++k++r+ ++aRpDI+HqcLl+lldsp+nkagllq+yiht+k+vlIev+p++RiPrtfkrFag
  EEA19637.1  36 VVLSNASLETYRSShggrngrEEKYSLLNSDEHIGVMRKMNRDISDARPDITHQCLLTLLDSPINKAGLLQIYIHTAKGVLIEVSPTVRIPRTFKRFAG 134
                 89***********999*********************************************************************************** PP

                 HHHHHHCCSEEEETTEE.SCEEEECS-HHHHCCC.SEEEEE-TTSEE-..................EEEE-SSSS......---HHEEESSSS---HHH CS
        EMG1  93 LmvqLLkklsirategeekLlkviknpitdhlppgskiillsesaekklvdleefv.....vkpvvfvigamskgsvki..dykeeeisisnypLsaav 184
                 LmvqLL++lsir+t+++ekLlkviknpitdhlpp++++++ls++a+  +v+++e++     ++++++++gam+kg++++  ++k+e i+isny+Lsa+v
  EEA19637.1 135 LMVQLLHRLSIRSTNSQEKLLKVIKNPITDHLPPNCRKVTLSFEAP--VVRVNEYIsslgpKESICVFVGAMAKGRDDFadEFKDEAIAISNYSLSASV 231
                 **********************************************..889*****9999999************8888899***************** PP

                 HHHHHHHHCH CS
        EMG1 185 vcskiltafE 194
                 +csk+++a E
  EEA19637.1 232 ACSKFCHAAE 241
                 *******987 PP

>> RP854  Uncharacterized protein RP854
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0      0.61   5.5e+03      60      79 ..      60      79 ..      57      92 .. 0.66
   2 ?   12.4   0.0   1.1e-05       0.1      63     151 ..     148     237 ..     134     244 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 0.61
       RP854 60 ysvinskeeilesykkyvdl 79
                ys++ns e i    k   d+
  EEA19637.1 60 YSLLNSDEHIGVMRKMNRDI 79
                88888888876555554444 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 1.1e-05
       RP854  63 inskeeilesykkyvdlsvpkss.vsclnyqelipkikslrskydlvepidvsinsvffknnvqviegeneaihvnnysinikyacadfl 151
                  ns+e++l+  k+ ++  +p +     l ++  + +++   s     e i v++ ++    +  + e ++eai + nys+    ac+ f 
  EEA19637.1 148 TNSQEKLLKVIKNPITDHLPPNCrKVTLSFEAPVVRVNEYISSLGPKESICVFVGAMAKGRDDFADEFKDEAIAISNYSLSASVACSKFC 237
                 6999********999888887661567999999******99*99************999999999*********************9995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (247 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       375  (0.0209158); expected 358.6 (0.02)
Passed bias filter:                      361  (0.020135); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.39u 0.27s 00:00:00.66 Elapsed: 00:00:00.40
# Mc/sec: 1835.51
//
Query:       EEA19638.1  [L=710]
Description: glyoxalase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
       0.01   16.0   0.8      0.028   14.6   0.0    2.2  3  Glyoxalase       Glyoxalase/Bleomycin resistance protein/Diox
      0.024   14.6   0.3      0.056   13.5   0.3    1.6  1  Gly-zipper_Omp   Glycine zipper
       0.16   11.9   2.1       0.41   10.5   2.1    1.7  1  Rick_17kDa_Anti  Glycine zipper 2TM domain


Domain annotation for each model (and alignments):
>> Glyoxalase  Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.0   4.7e-06     0.028       2     127 ..       3     118 ..       2     119 .. 0.90
   2 ?   -2.5   0.0      0.94   5.6e+03      34      69 ..     166     201 ..     155     279 .. 0.72
   3 ?   -3.6   0.4         2   1.2e+04      56      66 ..     665     675 ..     619     685 .. 0.52

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 4.7e-06
                 EEEEEEEESHHHHHHHHHHHH...HTSEEEEEEEEEESTEEEEEEEEETTTSEEEEEEEECCTTSCTHHCCBSCTSEEEEEEEEEHCHHHHHHHHHHHT CS
  Glyoxalase   2 idhvallvgdleksldFYtkv...LGfklvkktdnteeteglriaffhaggghielvlneapsgaakhvkkieetvhhvafialdvedvgkaldrlkea 97 
                 ++h++l v++l  s++F+  +   LG k + + d         i+f+   +  + + l++  +g +++        +h+af a ++e v  ++  + +a
  EEA19638.1   3 LAHLTLTVSHLPTSTSFFLAClqpLGYKFIGRHD-------EYIGFGSKADEPADFWLAQEQPGTPAGA-------AHIAFPAPNKEAVNTFFISALKA 87 
                 68*******************88899*****999.......89999999*******************9.......9********************** PP

                 TGEEEEEEECHHCTEEEEE.EEEETTSEEEE CS
  Glyoxalase  98 gvkvvaepgrhyfgalysf.yfrDpdGille 127
                 g+ +++ep+ + ++ +y+   + D dG+ +e
  EEA19638.1  88 GGTIHGEPKCRDPETGYFSaAVVDFDGNSIE 118
                 ********97776666643478888888777 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.94
                 EESTEEEEEEEEETTTSEEEEEEEECCTTSCTHHCC CS
  Glyoxalase  34 teeteglriaffhaggghielvlneapsgaakhvkk 69 
                 t+e+  + +a   +   ++++++ +aps aa ++++
  EEA19638.1 166 TTEDRAVQAAIENIPPSRVKMLDQQAPSQAAYQQQQ 201
                 555666666666777788888888888888877754 PP

  == domain 3  score: -3.6 bits;  conditional E-value: 2
                 EEECCTTSCTH CS
  Glyoxalase  56 lneapsgaakh 66 
                 ++++ s+  +h
  EEA19638.1 665 HRHSSSSHHSH 675
                 22222222222 PP

>> Gly-zipper_Omp  Glycine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.3   9.3e-06     0.056      24      42 ..     220     238 ..     212     242 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 9.3e-06
  Gly-zipper_Omp  24 aliGAavGaavGgliGaam 42 
                     ++iG+ +Ga++G++i++am
      EEA19638.1 220 TIIGTLLGATAGAAIAYAM 238
                     789*************999 PP

>> Rick_17kDa_Anti  Glycine zipper 2TM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   2.1   6.9e-05      0.41      23      41 ..     220     238 ..     214     238 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 6.9e-05
  Rick_17kDa_Anti  23 rvlGavvGAaaGavaGnai 41 
                      +++G+++GA aGa+++ a+
       EEA19638.1 220 TIIGTLLGATAGAAIAYAM 238
                      6789999999999998775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (710 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1272  (0.0709465); expected 358.6 (0.02)
Passed bias filter:                      379  (0.0211389); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.91u 0.32s 00:00:01.23 Elapsed: 00:00:00.50
# Mc/sec: 4285.59
//
Query:       EEA19639.1  [L=147]
Description: ubiquitin conjugating enzyme (UbcD), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    7.4e-52  174.7   0.0    8.3e-52  174.6   0.0    1.0  1  UQ_con     Ubiquitin-conjugating enzyme
  ------ inclusion threshold ------
      0.049   13.9   0.0      0.059   13.7   0.0    1.2  1  RWD        RWD domain
      0.059   13.2   0.0      0.092   12.6   0.0    1.3  1  UEV        UEV domain
      0.076   12.7   0.0      0.095   12.4   0.0    1.1  1  Prok-E2_B  Prokaryotic E2 family B


Domain annotation for each model (and alignments):
>> UQ_con  Ubiquitin-conjugating enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  174.6   0.0   1.9e-55   8.3e-52       1     139 [.       5     141 ..       5     142 .. 0.98

  Alignments for each domain:
  == domain 1  score: 174.6 bits;  conditional E-value: 1.9e-55
                 HHHHHHHHHHHSTTTTEEEEEEETTEECEEEEEEEB.TTSTTTTEEEEEEEE--TTTTTS--EEEESST-SCTTBETTSBB-CGGGSTTT--TTSHHHH CS
      UQ_con   1 rlqkelkelakkkpsgisaklvddenlfewkvlikgpedtpYeggvFklelefpedYPlkpPkvkfvtkifHPnvdksGevcldiLkeekWspaltles 99 
                 r++kel++l +++ps++sa+++ d +lf+w+++i+gp+d+pY ggvF l ++fp+dYP+k+Pkv+f+t+i+HPn++++G++cldiL+++ Wspalt+++
  EEA19639.1   5 RINKELTDLGRDPPSSCSAGPIGD-DLFHWQATIMGPSDSPYSGGVFFLAIHFPTDYPFKAPKVNFTTRIYHPNINSNGSICLDILRDQ-WSPALTISK 101
                 799********************8.**************************************************************77.********* PP

                 HHHHHHHHHHS--TTS-SSHHHHHHHHHTHHHHHHHHHHH CS
      UQ_con 100 vllsiqsLlaepnpesplnkeaakllkkdreeykkkvkey 139
                 vllsi+s+l++pnp++pl  e+a+ +k+dr++y+++++e+
  EEA19639.1 102 VLLSICSMLTDPNPDDPLVPEIAHVYKTDRARYDATAREW 141
                 ***********************************99886 PP

>> RWD  RWD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   1.3e-05     0.059      55     109 ..      50     107 ..      16     113 .. 0.74

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.3e-05
                 EEEEEEE-SSTTSS--EEEEEECC...SS-HHHHHHHHHHHHHHHHHT.TTS--CHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxx RF
         RWD  55 lkleiklpeeYPeeaPiislsste...nlpkeqvksleekleelaeen.lgepvifali 109
                 + l i++p +YP +aP++++++     n+ ++  + + + l+++++       v+ +++
  EEA19639.1  50 FFLAIHFPTDYPFKAPKVNFTTRIyhpNI-NSNGSICLDILRDQWSPAlTISKVLLSIC 107
                 6689***************9998833322.23333356666666665544555555555 PP

>> UEV  UEV domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   2.1e-05     0.092      53     117 ..      53     112 ..      44     119 .. 0.70

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 2.1e-05
                 EEE--TTTTTS--EEEE-GCC--TSGGGGGB-TTSBB--HHHH.S--TTT--HHHHHHHHHH---- CS
         UEV  53 liwvlesyPveaPivyvkptksmvikknenvdaqGlvylpyLe.eWkreksnlvslvqelaqafee 117
                  i  + +yP++aP v  + +       + n++++G + l++L+ +W++ + ++++++ +++++ ++
  EEA19639.1  53 AIHFPTDYPFKAPKVNFTTRI-----YHPNINSNGSICLDILRdQWSP-ALTISKVLLSICSMLTD 112
                 578899999999987554333.....3559************835776.66666665555554444 PP

>> Prok-E2_B  Prokaryotic E2 family B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   2.1e-05     0.095      33     108 ..      45     114 ..      28     132 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2.1e-05
   Prok-E2_B  33 tsggtvdlrlvypdsfpllppavflqdpeqlkllpHintfggaLClleeeldldewdpngsvadvleqlqqvLn.eg 108
                  sgg++ l++ +p ++p+  p+v  + +      p in+ +g +Cl       d+w p+ ++ +vl ++  +L+  +
  EEA19639.1  45 YSGGVFFLAIHFPTDYPFKAPKVNFTTRI---YHPNINS-NGSICL---DILRDQWSPALTISKVLLSICSMLTdPN 114
                 389**********************9999...6799999.9*****...8999************988888887455 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (147 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       236  (0.013163); expected 358.6 (0.02)
Passed bias filter:                      226  (0.0126053); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.56u 0.36s 00:00:00.92 Elapsed: 00:00:00.57
# Mc/sec: 772.13
//
Query:       EEA19640.1  [L=110]
Description: ubiquitin conjugating enzyme (UbcD), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.1e-42  145.0   0.0    1.3e-42  144.8   0.0    1.0  1  UQ_con     Ubiquitin-conjugating enzyme
  ------ inclusion threshold ------
       0.03   14.2   0.0      0.048   13.5   0.0    1.3  1  UEV        UEV domain
      0.032   14.5   0.0      0.043   14.1   0.0    1.2  1  RWD        RWD domain
      0.059   13.1   0.0      0.072   12.8   0.0    1.1  1  Prok-E2_B  Prokaryotic E2 family B


Domain annotation for each model (and alignments):
>> UQ_con  Ubiquitin-conjugating enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  144.8   0.0   2.8e-46   1.3e-42      35     139 ..       1     104 [.       1     105 [. 0.98

  Alignments for each domain:
  == domain 1  score: 144.8 bits;  conditional E-value: 2.8e-46
                 EB.TTSTTTTEEEEEEEE--TTTTTS--EEEESST-SCTTBETTSBB-CGGGSTTT--TTSHHHHHHHHHHHHHHS--TTS-SSHHHHHHHHHTHHHHH CS
      UQ_con  35 kgpedtpYeggvFklelefpedYPlkpPkvkfvtkifHPnvdksGevcldiLkeekWspaltlesvllsiqsLlaepnpesplnkeaakllkkdreeyk 133
                 +gp+d+pY ggvF l ++fp+dYP+k+Pkv+f+t+i+HPn++++G++cldiL+++ Wspalt+++vllsi+s+l++pnp++pl  e+a+ +k+dr++y+
  EEA19640.1   1 MGPSDSPYSGGVFFLAIHFPTDYPFKAPKVNFTTRIYHPNINSNGSICLDILRDQ-WSPALTISKVLLSICSMLTDPNPDDPLVPEIAHVYKTDRARYD 98 
                 69***************************************************77.******************************************* PP

                 HHHHHH CS
      UQ_con 134 kkvkey 139
                 ++++e+
  EEA19640.1  99 ATAREW 104
                 *99986 PP

>> UEV  UEV domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   1.1e-05     0.048      53     117 ..      16      75 ..      11      82 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 1.1e-05
                 EEE--TTTTTS--EEEE-GCC--TSGGGGGB-TTSBB--HHHH.S--TTT--HHHHHHHHHH---- CS
         UEV  53 liwvlesyPveaPivyvkptksmvikknenvdaqGlvylpyLe.eWkreksnlvslvqelaqafee 117
                  i  + +yP++aP v  + +       + n++++G + l++L+ +W++ + ++++++ +++++ ++
  EEA19640.1  16 AIHFPTDYPFKAPKVNFTTRI-----YHPNINSNGSICLDILRdQWSP-ALTISKVLLSICSMLTD 75 
                 578899999999987554333.....3559************835776.66666665555554444 PP

>> RWD  RWD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   9.6e-06     0.043      56     110 ..      14      71 ..       6      76 .. 0.68

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 9.6e-06
                 EEEEEE-SSTTSS--EEEEEECC...SS-HHHHHHHHHHHHHHHHHT.TTS--CHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxx RF
         RWD  56 kleiklpeeYPeeaPiislsste...nlpkeqvksleekleelaeen.lgepvifalid 110
                  l i++p +YP +aP++++++     n+ ++  + + + l+++++       v+ ++++
  EEA19640.1  14 FLAIHFPTDYPFKAPKVNFTTRIyhpNI-NSNGSICLDILRDQWSPAlTISKVLLSICS 71 
                 689***************9998843322.233333666667777665555555555555 PP

>> Prok-E2_B  Prokaryotic E2 family B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   1.6e-05     0.072      34     109 ..       9      78 ..       3      96 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.6e-05
   Prok-E2_B  34 sggtvdlrlvypdsfpllppavflqdpeqlkllpHintfggaLClleeeldldewdpngsvadvleqlqqvLn.egi 109
                 sgg++ l++ +p ++p+  p+v  + +      p in+ +g +Cl       d+w p+ ++ +vl ++  +L+  ++
  EEA19640.1   9 SGGVFFLAIHFPTDYPFKAPKVNFTTRI---YHPNINS-NGSICL---DILRDQWSPALTISKVLLSICSMLTdPNP 78 
                 899*********************9999...6799999.9*****...9999*************888888874555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (110 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       237  (0.0132188); expected 358.6 (0.02)
Passed bias filter:                      223  (0.0124379); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.56u 0.37s 00:00:00.93 Elapsed: 00:00:00.58
# Mc/sec: 571.35
//
Query:       EEA19641.1  [L=110]
Description: ubiquitin conjugating enzyme (UbcD), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.1e-42  145.0   0.0    1.3e-42  144.8   0.0    1.0  1  UQ_con     Ubiquitin-conjugating enzyme
  ------ inclusion threshold ------
       0.03   14.2   0.0      0.048   13.5   0.0    1.3  1  UEV        UEV domain
      0.032   14.5   0.0      0.043   14.1   0.0    1.2  1  RWD        RWD domain
      0.059   13.1   0.0      0.072   12.8   0.0    1.1  1  Prok-E2_B  Prokaryotic E2 family B


Domain annotation for each model (and alignments):
>> UQ_con  Ubiquitin-conjugating enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  144.8   0.0   2.8e-46   1.3e-42      35     139 ..       1     104 [.       1     105 [. 0.98

  Alignments for each domain:
  == domain 1  score: 144.8 bits;  conditional E-value: 2.8e-46
                 EB.TTSTTTTEEEEEEEE--TTTTTS--EEEESST-SCTTBETTSBB-CGGGSTTT--TTSHHHHHHHHHHHHHHS--TTS-SSHHHHHHHHHTHHHHH CS
      UQ_con  35 kgpedtpYeggvFklelefpedYPlkpPkvkfvtkifHPnvdksGevcldiLkeekWspaltlesvllsiqsLlaepnpesplnkeaakllkkdreeyk 133
                 +gp+d+pY ggvF l ++fp+dYP+k+Pkv+f+t+i+HPn++++G++cldiL+++ Wspalt+++vllsi+s+l++pnp++pl  e+a+ +k+dr++y+
  EEA19641.1   1 MGPSDSPYSGGVFFLAIHFPTDYPFKAPKVNFTTRIYHPNINSNGSICLDILRDQ-WSPALTISKVLLSICSMLTDPNPDDPLVPEIAHVYKTDRARYD 98 
                 69***************************************************77.******************************************* PP

                 HHHHHH CS
      UQ_con 134 kkvkey 139
                 ++++e+
  EEA19641.1  99 ATAREW 104
                 *99986 PP

>> UEV  UEV domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   1.1e-05     0.048      53     117 ..      16      75 ..      11      82 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 1.1e-05
                 EEE--TTTTTS--EEEE-GCC--TSGGGGGB-TTSBB--HHHH.S--TTT--HHHHHHHHHH---- CS
         UEV  53 liwvlesyPveaPivyvkptksmvikknenvdaqGlvylpyLe.eWkreksnlvslvqelaqafee 117
                  i  + +yP++aP v  + +       + n++++G + l++L+ +W++ + ++++++ +++++ ++
  EEA19641.1  16 AIHFPTDYPFKAPKVNFTTRI-----YHPNINSNGSICLDILRdQWSP-ALTISKVLLSICSMLTD 75 
                 578899999999987554333.....3559************835776.66666665555554444 PP

>> RWD  RWD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   9.6e-06     0.043      56     110 ..      14      71 ..       6      76 .. 0.68

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 9.6e-06
                 EEEEEE-SSTTSS--EEEEEECC...SS-HHHHHHHHHHHHHHHHHT.TTS--CHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxx RF
         RWD  56 kleiklpeeYPeeaPiislsste...nlpkeqvksleekleelaeen.lgepvifalid 110
                  l i++p +YP +aP++++++     n+ ++  + + + l+++++       v+ ++++
  EEA19641.1  14 FLAIHFPTDYPFKAPKVNFTTRIyhpNI-NSNGSICLDILRDQWSPAlTISKVLLSICS 71 
                 689***************9998843322.233333666667777665555555555555 PP

>> Prok-E2_B  Prokaryotic E2 family B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   1.6e-05     0.072      34     109 ..       9      78 ..       3      96 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.6e-05
   Prok-E2_B  34 sggtvdlrlvypdsfpllppavflqdpeqlkllpHintfggaLClleeeldldewdpngsvadvleqlqqvLn.egi 109
                 sgg++ l++ +p ++p+  p+v  + +      p in+ +g +Cl       d+w p+ ++ +vl ++  +L+  ++
  EEA19641.1   9 SGGVFFLAIHFPTDYPFKAPKVNFTTRI---YHPNINS-NGSICL---DILRDQWSPALTISKVLLSICSMLTdPNP 78 
                 899*********************9999...6799999.9*****...9999*************888888874555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (110 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       237  (0.0132188); expected 358.6 (0.02)
Passed bias filter:                      223  (0.0124379); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.56u 0.34s 00:00:00.90 Elapsed: 00:00:00.55
# Mc/sec: 606.32
//
Query:       EEA19642.1  [L=426]
Description: glutaryl-CoA dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.4e-27   94.7   0.2      1e-26   93.8   0.2    1.5  1  Acyl-CoA_dh_N  Acyl-CoA dehydrogenase, N-terminal domain
      2e-24   86.5   0.3      2e-24   86.5   0.3    1.6  2  Acyl-CoA_dh_1  Acyl-CoA dehydrogenase, C-terminal domain
    6.8e-16   58.3   0.0    1.2e-15   57.4   0.0    1.4  1  Acyl-CoA_dh_M  Acyl-CoA dehydrogenase, middle domain
    3.6e-07   30.5   0.4    3.6e-07   30.5   0.4    1.8  2  Acyl-CoA_dh_2  Acyl-CoA dehydrogenase, C-terminal domain


Domain annotation for each model (and alignments):
>> Acyl-CoA_dh_N  Acyl-CoA dehydrogenase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.8   0.2   2.3e-30     1e-26       1     113 []      46     157 ..      46     157 .. 0.98

  Alignments for each domain:
  == domain 1  score: 93.8 bits;  conditional E-value: 2.3e-30
                    THHHHHHHHHHHHHHHHHTHHHHHHHHHHTSGHHHHHHHHHHTTCTSTTS-GGGTS--S-HHHHHHHHHHHHHH-HHHHHHHHHHHHTTHHHHHHH CS
  Acyl-CoA_dh_N   1 teeqealrdtvrefaeeelaphaaewdeegefprelwkklaelGllgitvpeeygGagldyleaaivaeelaradaglalllgvhsslvapailrf 96 
                    tee+ a+rdt+r++++e+l p++ e+++++ ++r+++++++e Gllg ++ e y +ag++++++ +++ e++r+d+g++++++v+ssl++  i +f
     EEA19642.1  46 TEEELAIRDTARQYCQERLMPRVLEAYRKEDYDRKILEEMGEIGLLGASI-EGYECAGASTVASGLITKEVERVDSGYRSGMSVQSSLIMTGIHEF 140
                    79************************************************.9******************************************** PP

                    S-HHHHHHHHHHHHTTS CS
  Acyl-CoA_dh_N  97 GteeqkrryLpklasge 113
                    Gt+eqk+r+Lp+la+g+
     EEA19642.1 141 GTQEQKDRFLPQLAKGK 157
                    **************995 PP

>> Acyl-CoA_dh_1  Acyl-CoA dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.2       1.4   6.2e+03      25      48 ..       5      28 ..       1      36 [. 0.54
   2 !   86.5   0.3   4.4e-28     2e-24       3     149 ..     272     419 ..     270     420 .. 0.97

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1.4
                   HHHHHHHHHHHHHHTSB-CC-BGG CS
  Acyl-CoA_dh_1 25 larraleealeyarrrkafgkpli 48
                   l r+a +++++ a  r++  ++  
     EEA19642.1  5 LVRSAARQLRASALARHQTRRWAS 28
                   555556666666666666555544 PP

  == domain 2  score: 86.5 bits;  conditional E-value: 4.4e-28
                    HHHHHTTTT--S-----..-SHHHHHHHHHHHHHHHTSB-CC.-BGGGSHHHHHHHHHHHHHHHHHHHHHHHHHH--------HHHHHHHHHHHHH CS
  Acyl-CoA_dh_1   3 GfrvametlnheRlavaaaalglarraleealeyarrrkafg.kplidhqlvreklaemaaeleaarllvyraaealdagkpdraeasmaKlfase 97 
                    G+    + ln  Rl++a +  g+++  + +a+eya +rk+f   pl+++ql+++kla+  ++++   l++ ++a++ dagk ++  +sm+K + ++
     EEA19642.1 272 GLSGPFTCLNSARLGIAFGVTGALEDSISRAREYALDRKQFRgNPLAKYQLIQKKLADASTDAAFGTLAAIQVARLKDAGKSTPEMISMIKRQNCD 367
                    66666789*********************************889**************************************************** PP

                    HHHHHHHHHHHHHGGGTTSGGGHHHHHHHHTHHHHHSSS-HHHHHHHHHHHH CS
  Acyl-CoA_dh_1  98 laqevadlamqllGgaGyleeypverlyrdarvlrigeGtseiqrniiarrl 149
                     a   a+   +++Gg+++++ey++ r++ +  v++ +eG s+i+ +i++r++
     EEA19642.1 368 RALANARTLQEIFGGNATSDEYHIGRHVANLFVTQTYEGQSDIHALILGRAM 419
                    *************************************************997 PP

>> Acyl-CoA_dh_M  Acyl-CoA dehydrogenase, middle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.4   0.0   2.7e-19   1.2e-15       1      97 []     161     259 ..     161     259 .. 0.90

  Alignments for each domain:
  == domain 1  score: 57.4 bits;  conditional E-value: 2.7e-19
                    EEE---SS-SS-GGG---EEEEETT.E..EEEEEEEEEEETTTT-SEEEEEEETS-------EEEEEEE..GG...GEEE-----BSS-TTS-EEE CS
  Acyl-CoA_dh_M   1 afalTEpqaGsdvasvkttaaerdgge..yvlnGeKiwitnaaiatlalvlartekpdrarglslflvprdap...gvsvrrieeklGlrglptge 91 
                    +f+lTEp++Gsd  s++t a e+ +++  y l+G+K+witn++i++++lv+a+   ++ +++++ fl++r++     ++   i++k++lr   tg 
     EEA19642.1 161 CFGLTEPNHGSDPGSMETVAREHPTKKgfYSLSGSKTWITNSPISDVLLVWAK--LES-TGKIKGFLIERSKCppgTLETPAIKNKTALRASITGM 253
                    9*****************88776665567************************..555.789*******76656888999**************** PP

                    EEEE.. CS
  Acyl-CoA_dh_M  92 lvfedv 97 
                    ++++++
     EEA19642.1 254 IQMDNC 259
                    ***997 PP

>> Acyl-CoA_dh_2  Acyl-CoA dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.2      0.88     4e+03      53      68 ..       9      24 ..       3      46 .. 0.61
   2 !   30.5   0.4   8.1e-11   3.6e-07       1     131 [.     285     406 ..     285     409 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.88
                   HHHHHHHHHHHHHHHH CS
  Acyl-CoA_dh_2 53 AAralleraaaraeal 68
                   AAr+l ++a ar++  
     EEA19642.1  9 AARQLRASALARHQTR 24
                   5555555555554433 PP

  == domain 2  score: 30.5 bits;  conditional E-value: 8.1e-11
                    .HHHHHHHHHHHHHHHHHHHHHHHHHCTTT-------HHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHTT----HHHHHHHHHHHHHHHHHHH CS
  Acyl-CoA_dh_2   1 lgiaavalGaAraalaefvelarervrassgekladdpatqlalaeaaarldAArall.eraaaraealaaagkevtvedraearraaalavelai 95 
                    lgia  ++Ga++  +  + e+a +r++   g++la  + +q +la+a+++  AA  +l + ++ar   l +agk+ t+e+   ++r+     ++a 
     EEA19642.1 285 LGIAFGVTGALEDSISRAREYALDRKQ-FRGNPLAKYQLIQKKLADASTD--AAFGTLaAIQVAR---LKDAGKS-TPEMISMIKRQ---NCDRAL 370
                    5789999********************.******************9986..4444440334444...4778887.67766655555...579*** PP

                    HHHHHHHHHCGGGGGBTT-HHHHHHHHHHHHCTSGG CS
  Acyl-CoA_dh_2  96 aavdalfeaaGgsalrkesplqRlwRDahaaaaHaa 131
                    a ++ l e++Gg+a+ +e+++ R+  ++ +++++++
     EEA19642.1 371 ANARTLQEIFGGNATSDEYHIGRHVANLFVTQTYEG 406
                    ******************************999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (426 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       453  (0.0252663); expected 358.6 (0.02)
Passed bias filter:                      410  (0.022868); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.66u 0.36s 00:00:01.02 Elapsed: 00:00:00.55
# Mc/sec: 2337.94
//
Query:       EEA19643.1  [L=342]
Description: glutaryl-CoA dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.1e-25   87.6   0.3    1.2e-24   87.2   0.3    1.2  1  Acyl-CoA_dh_1  Acyl-CoA dehydrogenase, C-terminal domain
    2.5e-16   60.4   0.2    4.5e-16   59.5   0.2    1.5  1  Acyl-CoA_dh_N  Acyl-CoA dehydrogenase, N-terminal domain
    4.6e-16   58.8   0.0    8.2e-16   58.0   0.0    1.4  1  Acyl-CoA_dh_M  Acyl-CoA dehydrogenase, middle domain
    1.6e-07   31.7   0.4    2.3e-07   31.1   0.4    1.3  1  Acyl-CoA_dh_2  Acyl-CoA dehydrogenase, C-terminal domain


Domain annotation for each model (and alignments):
>> Acyl-CoA_dh_1  Acyl-CoA dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.2   0.3   2.7e-28   1.2e-24       3     149 ..     188     335 ..     186     336 .. 0.97

  Alignments for each domain:
  == domain 1  score: 87.2 bits;  conditional E-value: 2.7e-28
                    HHHHHTTTT--S-----..-SHHHHHHHHHHHHHHHTSB-CC.-BGGGSHHHHHHHHHHHHHHHHHHHHHHHHHH--------HHHHHHHHHHHHH CS
  Acyl-CoA_dh_1   3 GfrvametlnheRlavaaaalglarraleealeyarrrkafg.kplidhqlvreklaemaaeleaarllvyraaealdagkpdraeasmaKlfase 97 
                    G+    + ln  Rl++a +  g+++  + +a+eya +rk+f   pl+++ql+++kla+  ++++   l++ ++a++ dagk ++  +sm+K + ++
     EEA19643.1 188 GLSGPFTCLNSARLGIAFGVTGALEDSISRAREYALDRKQFRgNPLAKYQLIQKKLADASTDAAFGTLAAIQVARLKDAGKSTPEMISMIKRQNCD 283
                    66666789*********************************889**************************************************** PP

                    HHHHHHHHHHHHHGGGTTSGGGHHHHHHHHTHHHHHSSS-HHHHHHHHHHHH CS
  Acyl-CoA_dh_1  98 laqevadlamqllGgaGyleeypverlyrdarvlrigeGtseiqrniiarrl 149
                     a   a+   +++Gg+++++ey++ r++ +  v++ +eG s+i+ +i++r++
     EEA19643.1 284 RALANARTLQEIFGGNATSDEYHIGRHVANLFVTQTYEGQSDIHALILGRAM 335
                    *************************************************997 PP

>> Acyl-CoA_dh_N  Acyl-CoA dehydrogenase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.5   0.2     1e-19   4.5e-16      40     113 .]       1      73 [.       1      73 [. 0.98

  Alignments for each domain:
  == domain 1  score: 59.5 bits;  conditional E-value: 1e-19
                    HHHTTCTSTTS-GGGTS--S-HHHHHHHHHHHHHH-HHHHHHHHHHHHTTHHHHHHHS-HHHHHHHHHHHHTTS CS
  Acyl-CoA_dh_N  40 laelGllgitvpeeygGagldyleaaivaeelaradaglalllgvhsslvapailrfGteeqkrryLpklasge 113
                    ++e Gllg ++ e y +ag++++++ +++ e++r+d+g++++++v+ssl++  i +fGt+eqk+r+Lp+la+g+
     EEA19643.1   1 MGEIGLLGASI-EGYECAGASTVASGLITKEVERVDSGYRSGMSVQSSLIMTGIHEFGTQEQKDRFLPQLAKGK 73 
                    89*********.9**********************************************************995 PP

>> Acyl-CoA_dh_M  Acyl-CoA dehydrogenase, middle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.0   0.0   1.8e-19   8.2e-16       1      97 []      77     175 ..      77     175 .. 0.90

  Alignments for each domain:
  == domain 1  score: 58.0 bits;  conditional E-value: 1.8e-19
                    EEE---SS-SS-GGG---EEEEETT.E..EEEEEEEEEEETTTT-SEEEEEEETS-------EEEEEEE..GG...GEEE-----BSS-TTS-EEE CS
  Acyl-CoA_dh_M   1 afalTEpqaGsdvasvkttaaerdgge..yvlnGeKiwitnaaiatlalvlartekpdrarglslflvprdap...gvsvrrieeklGlrglptge 91 
                    +f+lTEp++Gsd  s++t a e+ +++  y l+G+K+witn++i++++lv+a+   ++ +++++ fl++r++     ++   i++k++lr   tg 
     EEA19643.1  77 CFGLTEPNHGSDPGSMETVAREHPTKKgfYSLSGSKTWITNSPISDVLLVWAK--LES-TGKIKGFLIERSKCppgTLETPAIKNKTALRASITGM 169
                    9*****************88776665567************************..555.789*******76656888999**************** PP

                    EEEE.. CS
  Acyl-CoA_dh_M  92 lvfedv 97 
                    ++++++
     EEA19643.1 170 IQMDNC 175
                    ***997 PP

>> Acyl-CoA_dh_2  Acyl-CoA dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.1   0.4   5.2e-11   2.3e-07       1     131 [.     201     322 ..     201     325 .. 0.84

  Alignments for each domain:
  == domain 1  score: 31.1 bits;  conditional E-value: 5.2e-11
                    .HHHHHHHHHHHHHHHHHHHHHHHHHCTTT-------HHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHTT----HHHHHHHHHHHHHHHHHHH CS
  Acyl-CoA_dh_2   1 lgiaavalGaAraalaefvelarervrassgekladdpatqlalaeaaarldAArall.eraaaraealaaagkevtvedraearraaalavelai 95 
                    lgia  ++Ga++  +  + e+a +r++   g++la  + +q +la+a+++  AA  +l + ++ar   l +agk+ t+e+   ++r+     ++a 
     EEA19643.1 201 LGIAFGVTGALEDSISRAREYALDRKQ-FRGNPLAKYQLIQKKLADASTD--AAFGTLaAIQVAR---LKDAGKS-TPEMISMIKRQ---NCDRAL 286
                    5789999********************.******************9986..4444440334444...4778887.67766655555...579*** PP

                    HHHHHHHHHCGGGGGBTT-HHHHHHHHHHHHCTSGG CS
  Acyl-CoA_dh_2  96 aavdalfeaaGgsalrkesplqRlwRDahaaaaHaa 131
                    a ++ l e++Gg+a+ +e+++ R+  ++ +++++++
     EEA19643.1 287 ANARTLQEIFGGNATSDEYHIGRHVANLFVTQTYEG 322
                    ******************************999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       247  (0.0137766); expected 358.6 (0.02)
Passed bias filter:                      234  (0.0130515); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.64u 0.33s 00:00:00.97 Elapsed: 00:00:00.55
# Mc/sec: 1878.77
//
Query:       EEA19644.1  [L=342]
Description: glutaryl-CoA dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.1e-25   87.6   0.3    1.2e-24   87.2   0.3    1.2  1  Acyl-CoA_dh_1  Acyl-CoA dehydrogenase, C-terminal domain
    2.5e-16   60.4   0.2    4.5e-16   59.5   0.2    1.5  1  Acyl-CoA_dh_N  Acyl-CoA dehydrogenase, N-terminal domain
    4.6e-16   58.8   0.0    8.2e-16   58.0   0.0    1.4  1  Acyl-CoA_dh_M  Acyl-CoA dehydrogenase, middle domain
    1.6e-07   31.7   0.4    2.3e-07   31.1   0.4    1.3  1  Acyl-CoA_dh_2  Acyl-CoA dehydrogenase, C-terminal domain


Domain annotation for each model (and alignments):
>> Acyl-CoA_dh_1  Acyl-CoA dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.2   0.3   2.7e-28   1.2e-24       3     149 ..     188     335 ..     186     336 .. 0.97

  Alignments for each domain:
  == domain 1  score: 87.2 bits;  conditional E-value: 2.7e-28
                    HHHHHTTTT--S-----..-SHHHHHHHHHHHHHHHTSB-CC.-BGGGSHHHHHHHHHHHHHHHHHHHHHHHHHH--------HHHHHHHHHHHHH CS
  Acyl-CoA_dh_1   3 GfrvametlnheRlavaaaalglarraleealeyarrrkafg.kplidhqlvreklaemaaeleaarllvyraaealdagkpdraeasmaKlfase 97 
                    G+    + ln  Rl++a +  g+++  + +a+eya +rk+f   pl+++ql+++kla+  ++++   l++ ++a++ dagk ++  +sm+K + ++
     EEA19644.1 188 GLSGPFTCLNSARLGIAFGVTGALEDSISRAREYALDRKQFRgNPLAKYQLIQKKLADASTDAAFGTLAAIQVARLKDAGKSTPEMISMIKRQNCD 283
                    66666789*********************************889**************************************************** PP

                    HHHHHHHHHHHHHGGGTTSGGGHHHHHHHHTHHHHHSSS-HHHHHHHHHHHH CS
  Acyl-CoA_dh_1  98 laqevadlamqllGgaGyleeypverlyrdarvlrigeGtseiqrniiarrl 149
                     a   a+   +++Gg+++++ey++ r++ +  v++ +eG s+i+ +i++r++
     EEA19644.1 284 RALANARTLQEIFGGNATSDEYHIGRHVANLFVTQTYEGQSDIHALILGRAM 335
                    *************************************************997 PP

>> Acyl-CoA_dh_N  Acyl-CoA dehydrogenase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.5   0.2     1e-19   4.5e-16      40     113 .]       1      73 [.       1      73 [. 0.98

  Alignments for each domain:
  == domain 1  score: 59.5 bits;  conditional E-value: 1e-19
                    HHHTTCTSTTS-GGGTS--S-HHHHHHHHHHHHHH-HHHHHHHHHHHHTTHHHHHHHS-HHHHHHHHHHHHTTS CS
  Acyl-CoA_dh_N  40 laelGllgitvpeeygGagldyleaaivaeelaradaglalllgvhsslvapailrfGteeqkrryLpklasge 113
                    ++e Gllg ++ e y +ag++++++ +++ e++r+d+g++++++v+ssl++  i +fGt+eqk+r+Lp+la+g+
     EEA19644.1   1 MGEIGLLGASI-EGYECAGASTVASGLITKEVERVDSGYRSGMSVQSSLIMTGIHEFGTQEQKDRFLPQLAKGK 73 
                    89*********.9**********************************************************995 PP

>> Acyl-CoA_dh_M  Acyl-CoA dehydrogenase, middle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.0   0.0   1.8e-19   8.2e-16       1      97 []      77     175 ..      77     175 .. 0.90

  Alignments for each domain:
  == domain 1  score: 58.0 bits;  conditional E-value: 1.8e-19
                    EEE---SS-SS-GGG---EEEEETT.E..EEEEEEEEEEETTTT-SEEEEEEETS-------EEEEEEE..GG...GEEE-----BSS-TTS-EEE CS
  Acyl-CoA_dh_M   1 afalTEpqaGsdvasvkttaaerdgge..yvlnGeKiwitnaaiatlalvlartekpdrarglslflvprdap...gvsvrrieeklGlrglptge 91 
                    +f+lTEp++Gsd  s++t a e+ +++  y l+G+K+witn++i++++lv+a+   ++ +++++ fl++r++     ++   i++k++lr   tg 
     EEA19644.1  77 CFGLTEPNHGSDPGSMETVAREHPTKKgfYSLSGSKTWITNSPISDVLLVWAK--LES-TGKIKGFLIERSKCppgTLETPAIKNKTALRASITGM 169
                    9*****************88776665567************************..555.789*******76656888999**************** PP

                    EEEE.. CS
  Acyl-CoA_dh_M  92 lvfedv 97 
                    ++++++
     EEA19644.1 170 IQMDNC 175
                    ***997 PP

>> Acyl-CoA_dh_2  Acyl-CoA dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.1   0.4   5.2e-11   2.3e-07       1     131 [.     201     322 ..     201     325 .. 0.84

  Alignments for each domain:
  == domain 1  score: 31.1 bits;  conditional E-value: 5.2e-11
                    .HHHHHHHHHHHHHHHHHHHHHHHHHCTTT-------HHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHTT----HHHHHHHHHHHHHHHHHHH CS
  Acyl-CoA_dh_2   1 lgiaavalGaAraalaefvelarervrassgekladdpatqlalaeaaarldAArall.eraaaraealaaagkevtvedraearraaalavelai 95 
                    lgia  ++Ga++  +  + e+a +r++   g++la  + +q +la+a+++  AA  +l + ++ar   l +agk+ t+e+   ++r+     ++a 
     EEA19644.1 201 LGIAFGVTGALEDSISRAREYALDRKQ-FRGNPLAKYQLIQKKLADASTD--AAFGTLaAIQVAR---LKDAGKS-TPEMISMIKRQ---NCDRAL 286
                    5789999********************.******************9986..4444440334444...4778887.67766655555...579*** PP

                    HHHHHHHHHCGGGGGBTT-HHHHHHHHHHHHCTSGG CS
  Acyl-CoA_dh_2  96 aavdalfeaaGgsalrkesplqRlwRDahaaaaHaa 131
                    a ++ l e++Gg+a+ +e+++ R+  ++ +++++++
     EEA19644.1 287 ANARTLQEIFGGNATSDEYHIGRHVANLFVTQTYEG 322
                    ******************************999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       247  (0.0137766); expected 358.6 (0.02)
Passed bias filter:                      234  (0.0130515); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.34s 00:00:00.88 Elapsed: 00:00:00.53
# Mc/sec: 1942.35
//
Query:       EEA19645.1  [L=577]
Description: NADPH oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.9e-33  115.8   0.0    2.9e-33  115.2   0.0    1.3  1  NAD_binding_6  Ferric reductase NAD binding domain
      4e-21   75.1   0.0    1.1e-20   73.8   0.0    1.7  1  FAD_binding_8  FAD-binding domain
    1.4e-19   70.4  10.6    1.4e-19   70.4  10.6    2.2  2  Ferric_reduct  Ferric reductase like transmembrane component
  ------ inclusion threshold ------
       0.07   13.8   0.0        0.3   11.7   0.0    2.1  1  NAD_binding_1  Oxidoreductase NAD-binding domain


Domain annotation for each model (and alignments):
>> NAD_binding_6  Ferric reductase NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.2   0.0   6.4e-37   2.9e-33       1     155 [.     413     560 ..     413     561 .. 0.92

  Alignments for each domain:
  == domain 1  score: 115.2 bits;  conditional E-value: 6.4e-37
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  NAD_binding_6   1 yenvllvagGiGitpfisilkdllkksk..kealktkkikliwvvressslewfkdvLneleeeksegnieihiYlTseyeaedasdqlissiege 94 
                    ye+ +lv++GiG+tpf+silk ++++++  k++++ +k+++ wv+r+ +s+ewfk +L+ +e ++ e++ieih+YlT + + +da++ +i+     
     EEA19645.1 413 YEVAMLVGAGIGVTPFASILKSIWYRMSrgKQQTRLRKVYFFWVCRDFGSFEWFKSLLSAIEAQDLESRIEIHTYLTAKIKPDDATNIMIND---A 505
                    7899************************9999*****************************************************9976666...3 PP

                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  NAD_binding_6  95 nseslkqgvdavsgtrnvkihfgRPnlkevlkdiaskhknssvgvfvCGppklvkevkklv 155
                    n+       d ++g+r + ++fgRPn++ +++++ + h  ++ gvf CGp++l  ++   +
     EEA19645.1 506 NA-----PQDTITGLR-APTNFGRPNWDMIFRSVRKIHSPAEAGVFFCGPKGLGSQLHIKC 560
                    32.....346799***.************************************99887555 PP

>> FAD_binding_8  FAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.8   0.0   2.3e-24   1.1e-20       7     108 ..     281     406 ..     276     407 .. 0.89

  Alignments for each domain:
  == domain 1  score: 73.8 bits;  conditional E-value: 2.3e-24
  FAD_binding_8   7 akvalleedliklkvskpkkslkykaGqyvyinipslsklfwqsHPFtiasapeddklslvikvksgltkklakkllsssk............... 87 
                     kv   ++++++++++k k     kaGqy+++ +p++s  +wq HPFt++sape+d++s++i+  +++tk lak l    +               
     EEA19645.1 281 SKVIQHPSNVVEIQIKKEKT--ITKAGQYIFLCCPEIS--LWQYHPFTLTSAPEEDYISVHIRCVGNFTKALAKTLGCEFEsgknkgkdgkgdasa 372
                    5788899************8..89**************..8*********************************997665678899********** PP

  FAD_binding_8  88 .............kelenkkaklkvlidGPYGap 108
                                 +++      +++ idGP+G++
     EEA19645.1 373 vvgidkigtgdkdLDPRIRRILPRIYIDGPFGSA 406
                    *********99665555555566********986 PP

>> Ferric_reduct  Ferric reductase like transmembrane component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.5      0.23     1e+03     101     120 ..      53      71 ..      40      95 .. 0.85
   2 !   70.4  10.6   3.2e-23   1.4e-19       6     123 ..     109     228 ..      99     229 .. 0.84

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.23
  Ferric_reduct 101 irrrlsyelFyylHhllyva 120
                    +r r++  lF ++++l+y++
     EEA19645.1  53 WR-RFTVFLFVLVQILVYIF 71 
                    77.88888888888888887 PP

  == domain 2  score: 70.4 bits;  conditional E-value: 3.2e-23
  Ferric_reduct   6 lillplall.la.lRnnflepltglsldklllfHkwlgvlafllallHvilyllnflrfsal...deerlldsllkkpynllGvlalllliilait 96 
                    lil+p+    ++ lR+++l+    +++dk+++fHk++++++++++++H+i++l n  + sa+    + ++l   + +   ++G+++l++l++++ t
     EEA19645.1 109 LILFPVCRTlISlLRQTPLN--GIIQFDKNITFHKLVAWAIVFFSWVHTIAHLNNVAQLSAKngqGFAGFLRAGFLTGPTWTGWIMLIALMLMVGT 202
                    55665544435578998887..6678*******************************999876654455566666666667*************** PP

  Ferric_reduct  97 SlkfirrrlsyelFyylHhllyvayll 123
                    S++  r r ++e F+y+Hhl++v++++
     EEA19645.1 203 SVEKPR-RANFERFWYTHHLFVVFFVF 228
                    ******.******************86 PP

>> NAD_binding_1  Oxidoreductase NAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   6.7e-05       0.3       1      76 [.     418     501 ..     418     556 .. 0.68

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 6.7e-05
                    EEEEGGGGHHHHHHHHHHHHHCT......TCSEEEEEEEESSGCGS.TTHHHHHHHHHHCTT.EEEEEEEESSCTTTSSSEESS CS
  NAD_binding_1   1 miagGtGiaPvrsvlraileeak......dktkvvlvyGnrteedl.lyreeleelakklpg.rlkvvavvsreeagweggkgr 76 
                    ++++G G++P+ s+l+ i  + +      + +kv++++ +r   ++  ++  l +++++  + r+++ ++++ + + ++  +  
     EEA19645.1 418 LVGAGIGVTPFASILKSIWYRMSrgkqqtRLRKVYFFWVCRDFGSFeWFKSLLSAIEAQDLEsRIEIHTYLTAKIKPDDATNIM 501
                    79*************999877334666777788999999998876623455555554444334555555544444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (577 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       687  (0.0383178); expected 358.6 (0.02)
Passed bias filter:                      402  (0.0224218); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.48
# Mc/sec: 3604.41
//
Query:       EEA19646.1  [L=463]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.8e-09   37.6  11.3    3.6e-09   36.6  11.3    1.5  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
    2.8e-09   36.4   0.5    4.6e-09   35.7   0.5    1.4  1  Fungal_trans  Fungal specific transcription factor domain
     0.0097   16.2   0.1      0.019   15.2   0.1    1.4  1  GGDEF_2       GGDEF-like domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.6  11.3     6e-13   3.6e-09       2      39 ..      11      47 ..      10      48 .. 0.91

  Alignments for each domain:
  == domain 1  score: 36.6 bits;  conditional E-value: 6e-13
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfysesskr 39
                +CdnCr++K++C++++P C +C + +l C++++  +++
  EEA19646.1 11 VCDNCRRRKIRCNREQP-CDKCLEISLVCEYNDIARRK 47
                7****************.************88777765 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.7   0.5   7.7e-13   4.6e-09       2     179 ..     134     302 ..     133     334 .. 0.74

  Alignments for each domain:
  == domain 1  score: 35.7 bits;  conditional E-value: 7.7e-13
  Fungal_trans   2 drffsnfhpqfpilhkpsflpkt..........ssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfssps 88 
                   ++f ++++p +p+++k+ +l +           +      sa a+  l l + +++a+    ++++s   l            r +  ++++f +  
    EEA19646.1 134 HVFLTYLYPIMPVVDKDALLLDCanpealgprrYALLVALSAAAHLQLNLDMPQTAATVDIPQSGQS---LL-----------REALRTLRQFDPLE 216
                   6788888888888888777777766666666655555555666666666888888888887777776...22...........33333333333333 PP

  Fungal_trans  89 s.s.lwilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrpplldds 179
                   + +  ++l  ++l++ y   +  + +++ +++  + +a+ l+L+ ++ y        l  +ea ++rR++w  F++++ +al++Grp++l+++
    EEA19646.1 217 DpHvDNVLTMFFLFAAYGNLRK-THQAWHYLNQSICFAYMLKLNVESTYTT------LNQHEADMLRRIYWLLFITERAYALQTGRPVMLRAT 302
                   3020245556666666665555.699999**********************......*******************************87765 PP

>> GGDEF_2  GGDEF-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.1   3.2e-06     0.019       8      49 ..     172     213 ..     167     246 .. 0.89

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 3.2e-06
     GGDEF_2   8 llerarrlgldldgpyvvvvieleedaerllraleealralg 49 
                 +l++a++l+l+ld p++++ +++++++++llr+  + lr+++
  EEA19646.1 172 ALSAAAHLQLNLDMPQTAATVDIPQSGQSLLREALRTLRQFD 213
                 5689*****************************999999984 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (463 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       474  (0.0264376); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.23s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 3316.42
//
Query:       EEA19647.1  [L=595]
Description: alpha-amylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.6e-116  389.6   0.3   6.7e-116  387.5   0.2    1.8  2  Alpha-amylase   Alpha amylase, catalytic domain
     0.0078   16.3   0.0      0.015   15.4   0.0    1.5  1  Malt_amylase_C  Maltogenic Amylase, C-terminal domain
  ------ inclusion threshold ------
      0.015   14.4   0.0      0.023   13.8   0.0    1.2  1  hDGE_amylase    Glycogen debranching enzyme, glucanotransfera


Domain annotation for each model (and alignments):
>> Alpha-amylase  Alpha amylase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  387.5   0.2  1.1e-119  6.7e-116       1     334 [.      43     398 ..      43     406 .. 0.97
   2 ?    0.1   0.0     0.079   4.7e+02     186     258 ..     408     479 ..     397     509 .. 0.75

  Alignments for each domain:
  == domain 1  score: 387.5 bits;  conditional E-value: 1.1e-119
                    --CHHHHCTCCCCCCCT-SCEEE-B-CE-S-TTTTSS-SCECCE-CCC--CCCCCCHHHHHHCTT-EEEEEE--SC--TTSCCCHCCHHSTTSGGG CS
  Alpha-amylase   1 GDLkGiiekLdYlkeLGvtaiwlsPifkspqadhgYdiadytkidpefGtnedlkeLiskahekgikvilDlVvNHtsdehewfkeslkkkgepkr 96 
                    GDLkGii+kLdY+++LGv+ +wl+Pif+spq d+gYdi+dy+ i+p +Gt+ed++ L + +h++g+k+++DlVvNHtsd+h wf+e++++  +p r
     EEA19647.1  43 GDLKGIISKLDYIQGLGVDIVWLNPIFSSPQVDMGYDISDYYDIHPPYGTMEDVNMLAEGLHKRGMKLLMDLVVNHTSDQHPWFQEAISSVSNPRR 138
                    9*********************************************************************************************** PP

                    CCC-E..........ESS-STTC-TTTTCSCEECTTTTCEEESSS-TTS-BB-TTTCCCCCCCCCCCCCCCTTT-SEEEETTCCCTTTCCCC.... CS
  Alpha-amylase  97 dyyiwkegk....eekeppnnwkslfdgsaweydekaqeyylhlflkklpdLnteneevrkelkdvvkfwlekgidGfRlDvvkhvskveal.... 184
                    d+yiwk++     ++++ppnnw s+f+gsaweyde ++eyylhlf+k++pdLn+en evrk++ ++++fwle+g+ GfR+Dv++ +sk++ +    
     EEA19647.1 139 DWYIWKKPIvgedGKPQPPNNWSSYFGGSAWEYDERSGEYYLHLFAKEQPDLNWENVEVRKAVHRIIRFWLERGVHGFRMDVINFISKDQSFpdaa 234
                    ******999999999*************************************************************************8888**** PP

                    .............HCCHCCHHHHHHHHHHHTCCGTT-EEEEE-TT-SC.CCHCCCC-CGG-SICECCITTCGGGCC-CTSTTSB-SS-HHHHHHHH CS
  Alpha-amylase 185 .............esngeflheftqalnetvasrkevmtvgEvssdas.edlrvyttearlelemvldfphldvaqkakikeqlksisakklkell 266
                                 +  g++lhe+ q++ +   ++++++ vgE+ + ++ ++  + +  +r el+m+++f+ ++++++   k + k+ ++++lk+++
     EEA19647.1 235 ivsnsrwqngsahYACGPRLHEYLQEIGAIL-KEYNAFSVGEMPEVNDyDEILKAVGFQRGELNMIFHFEIVSLDHGDGGKFTAKDWNMQELKSVV 329
                    ***********99999************876.9999*******98655156677788899************************************ PP

                    HHHHHHS-CCCTTCEEES--TTS--HHHHTTSSTTTT.HHHHHHHHHCCCTSSSEEEEETTCCCT---- CS
  Alpha-amylase 267 kkwlkaleeaaeeavtflgnHDqeRilsrlgddsaea.ekklklaaillltlrGvpviYyGeEigmtgg 334
                     kw+k ++e++ +++++l+nHDq+Ri+sr+g+d++e+ e+++k++a++l   +G+ +iY+G+E+gm ++
     EEA19647.1 330 LKWQKFMHENDGWNALYLENHDQPRIVSRFGSDQPENrEQSAKMLAAFLGFQSGTLFIYQGQELGMPNV 398
                    ***********************************999****************************997 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.079
                    CCHCCHHHHHHHHHHHTCCGTT-EEEEE-TT-SCCCHCC.CC-CGG-SICECCITTCGGGCC-CTSTTSB-SS- CS
  Alpha-amylase 186 sngeflheftqalnetvasrkevmtvgEvssdasedlrv.yttearlelemvldfphldvaqkakikeqlksis 258
                    ++ e+lh++++ + e     + ++ +gE+  ++++++r+ ++ +a +++ +  + p ++v+ +++++++ ++i+
     EEA19647.1 408 RDIETLHHWKEVVSEGL--ADPIVSLGEYRLKSRDNARTpMQWDASVNAGFSTSTPWISVHDDYQKFNAASQIT 479
                    67788999999999887..899999****999988887625667888888888899999999988755555554 PP

>> Malt_amylase_C  Maltogenic Amylase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   2.6e-06     0.015       1      43 [.     505     548 ..     505     578 .. 0.89

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 2.6e-06
                     -EEEE---S-TTEEEEEEEETT.EEEEEEEESS-EEEEE--GGG CS
  Malt_amylase_C   1 GsfefleadnrkvlaYlReyed.etilvvaNrsaqaveldlsel 43 
                     Gsf ++++++++ l Y+R ++     +vvaN+ + av ++ +++
      EEA19647.1 505 GSFDLISSEHPDMLGYMRVSDSgRVAVVVANFRPWAVAWTPPHF 548
                     9*******************99455788899*****99987755 PP

>> hDGE_amylase  Glycogen debranching enzyme, glucanotransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   3.9e-06     0.023      19     113 ..      43     129 ..      39     138 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 3.9e-06
                   -SHHHHHHHHHHHHHTT--EEEES--EEE-TT--TTSEEEEEEE-TTT-.....SSC.HHHHHHHHHHHHHH--EEEEEE--SEEETT-CCCCC- CS
  hDGE_amylase  19 GpleeWekvlkeikekgYnmiHftPlqelGesnSpYSiadqleldkelfeekdkeekeedveklvkklekeygllsltDvVlnHtannskwleeh 113
                   G l+   ++l+ i+  g +++ + P+ +  + +  Y i+d  ++++          ++edv+ l + l ++ g+  l+D+V nHt+++ +w +e 
    EEA19647.1  43 GDLKGIISKLDYIQGLGVDIVWLNPIFSSPQVDMGYDISDYYDIHPPYG-------TMEDVNMLAEGL-HKRGMKLLMDLVVNHTSDQHPWFQEA 129
                   6666666788889999999999999999999999999999999999884.......567887665555.5679999***************9985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (595 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       388  (0.0216409); expected 358.6 (0.02)
Passed bias filter:                      341  (0.0190195); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.61u 0.29s 00:00:00.89 Elapsed: 00:00:00.46
# Mc/sec: 3867.88
//
Query:       EEA19648.1  [L=536]
Description: MFS maltose permease MalP [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    9.8e-89  298.3  24.3    1.1e-88  298.1  24.3    1.0  1  Sugar_tr    Sugar (and other) transporter
    5.4e-21   74.9  46.9    2.6e-19   69.4  26.0    2.4  3  MFS_1       Major Facilitator Superfamily
    0.00049   18.8  23.6     0.0015   17.1   2.7    2.7  3  MFS_2       MFS/sugar transport protein
     0.0019   17.1  10.9      0.014   14.3   3.6    2.2  2  MFS_1_like  MFS_1 like family
  ------ inclusion threshold ------
        1.6    8.8   8.2       0.86    9.6   0.6    2.9  3  OppC_N      N-terminal TM domain of oligopeptide transport pe
        4.5    7.5   8.8       0.94    9.7   3.0    2.5  2  YtpI        YtpI-like protein
        7.4    6.2  13.8       0.29   10.8   0.2    2.9  3  DUF4131     Domain of unknown function (DUF4131)


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  298.1  24.3   4.4e-92   1.1e-88       3     452 .]      56     508 ..      54     508 .. 0.94

  Alignments for each domain:
  == domain 1  score: 298.1 bits;  conditional E-value: 4.4e-92
                 HHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS CS
    Sugar_tr   3 lvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgkns 101
                 l+++ + +++gYd+ ++g+f+++++f  ++g   s++s++ s+ ++  + ++++ G+i+G +  g++++rfG++k+++ + v +v  +++ ++a+   +
  EEA19648.1  56 LLISSAIIMEGYDVVLMGSFYAFPAFNERYGHRMSDGSYALSAQWQAGLSNAMNCGQILGLFANGIISERFGYRKTMMYSLVATVGFIFILFFAQ---N 151
                 56677779********************************999999999**********************************************...* PP

                 -TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHH CS
    Sugar_tr 102 vevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPrylve 200
                 v+ l+vg +l+Gi++G+ ++l+ +y+sE++p +lR +l+++ +l++++G+lva+++  gl++  +++ +ri++++q+v+++ ++i++l++PESP++lv 
  EEA19648.1 152 VQTLLVGEILMGIPLGVYQTLSVTYASEVCPVALRAYLTTYVNLCWVIGQLVASGVLKGLANRADQWAYRIPFAVQWVWPIPIFIGVLLAPESPWWLVR 250
                 ************************************************************666666********************************* PP

                 TT-HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH...........HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH..HH CS
    Sugar_tr 201 kgkeeeakevlaklrgeedadrelaeekdsleaeqeee......kaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsks..ll 291
                 kg++++a  +l++l  ++d d +++e ++++ ++ e e      +++++++ ++   ++r+ i ++++++q+l+G   +m ys+++++ +gl  s  + 
  EEA19648.1 251 KGRRDDAICSLKRLTSNSDTDFNAEETIAMMVHTNELEkeiavgTNYLDCFRGM--DLYRTEISCLIWAAQNLCG-SGLMAYSTVFYQRAGLPVSqsFN 346
                 *******************************99988878898966777777666..699****************.99*************876666** PP

                 HHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH...HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHH CS
    Sugar_tr 292 vtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilg.ivalllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskala 389
                 +++  +++ f+ t++++fl+ rfGRRtl+++G+a+ +++++++g i  ++ ++++   + +   +++++++++  ++gpv++ lv+E+ ++++R k+ a
  EEA19648.1 347 MSLAQYAIGFFGTVFSWFLMMRFGRRTLYVVGLAILTALLLVVGfISIAPATTNT---AWATGSMLLVYTFFYDSTVGPVCYSLVAEIPSTRLRIKTVA 442
                 ********************************************87777777775...5555667789999**************************** PP

                 HHHHHHHHHHHHHHHHHHHHHCHHH...T-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 390 iavavnwlanflisllfpiiteaig...ggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 +a ++ + +++l ++++p++++       g+ +++++gla+l  ++ ++ vpe kgrt  e+++lf
  EEA19648.1 443 LARNLYNCFSILNGVIIPYMLNVDAwnwRGKAGFFWGGLALLCWVWAYWRVPEPKGRTYAEMDALF 508
                 ********************986555688*********************************9987 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.2     0.048   1.2e+02     194     258 ..      37     116 ..      15     118 .. 0.66
   2 !   69.4  26.0     1e-22   2.6e-19      18     348 ..      77     452 ..      51     456 .. 0.74
   3 !   19.7  13.0   1.3e-07   0.00032      55     187 ..     365     505 ..     364     525 .. 0.72

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.048
       MFS_1 194 aplvpawkallkdpvl..willialllfffgfsg....lltllplylqevlgls..............glllaglllallalvga 258
                 + ++  w+ l+  p    w+lli++++++ g+       ++ +p + +e++g                g l+++  +  ++++g+
  EEA19648.1  37 HRMTL-WQGLRLYPKAvgWSLLISSAIIMEGYDVvlmgSFYAFPAF-NERYGHRmsdgsyalsaqwqaG-LSNA--MNCGQILGL 116
                 34444.9999999977678666666666444444444499999998.9999999777766666666655.6666..666666655 PP

  == domain 2  score: 69.4 bits;  conditional E-value: 1e-22
       MFS_1  18 alplalaedlg......ispseigllltl...yalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgagalfpaga 107
                 a+p a +e +g      + + ++++ ++l      g++++ +  G +s+rfG r++++ +l++++ ++++l+fa+++ +llv+ +l+G+  g++ ++++
  EEA19648.1  77 AFP-AFNERYGhrmsdgSYALSAQWQAGLsnaMNCGQILGLFANGIISERFGYRKTMMYSLVATVGFIFILFFAQNVQTLLVGEILMGIPLGVYQTLSV 174
                 344.4555555443333333346674444322666999999999***********************88888988988********************* PP

       MFS_1 108 aliadwfpkeergraigllsagfslGailgpllggllasslg...Wravfyilaivsllafvlfllllpeepperkrkspkeee............... 188
                 ++++++ p   r+  + ++++++ +G +++ ++   la  +    +r +f +  +  +  f+    +l++++++ + +++ ++                
  EEA19648.1 175 TYASEVCPVALRAYLTTYVNLCWVIGQLVASGVLKGLANRADqwaYRIPFAVQWVWPIPIFI---GVLLAPESPWWLVRKGRRDdaicslkrltsnsdt 270
                 ***************************99977777777666533455555555555555544...7776777766666666666778888888998877 PP

       MFS_1 189 ......................kgtgpaplvpawkallkdpvl.......w.....illialllfffgfsglltllplylqevlglsglllaglllall 253
                                       +gt                 l       +     ++li ++ + ++ sgl+++++++  ++ gl+ + ++  ++ + 
  EEA19648.1 271 dfnaeetiammvhtnelekeiaVGTNY---------------LdcfrgmdLyrteiSCLIWAAQN-LCGSGLMAYSTVF-YQRAGLP-VSQSFNMSLAQ 351
                 777777776666554433322222222...............12222222124454666666666.49999*******9.*******.89999999999 PP

       MFS_1 254 alvgailallagrlsdrlgrrrrlllallllllaalglallavt...ssavllll.vlvliGf.glgfvfpsllalasdlappeeagtasglfn.tags 346
                 +++g+++ +++ +l+ r+grr+  +++l++l++++l + +++ +   ++++++   +l++++f   ++v p   +l+++  +++ + + ++l+  ++++
  EEA19648.1 352 YAIGFFGTVFSWFLMMRFGRRTLYVVGLAILTALLLVVGFISIApatTNTAWATGsMLLVYTFfYDSTVGPVCYSLVAEIPSTRLRIKTVALARnLYNC 450
                 999999999999999*****9999999999999998888888888776666666668888999888999999999999999888877666666547777 PP

       MFS_1 347 lg 348
                 ++
  EEA19648.1 451 FS 452
                 76 PP

  == domain 3  score: 19.7 bits;  conditional E-value: 1.3e-07
       MFS_1  55 lsdrfGrrrvlllglllfalglllllf...a....sslw.lllvlrvlqGlga.galfpagaaliadwfpkeergraigllsagfslGailgpllggll 144
                 l+ rfGrr ++++gl+++ + ll+  f   a    ++ w +   l v   +++ +++ p++++l+a++ + + r + ++l+   +++ +il  ++ +++
  EEA19648.1 365 LMMRFGRRTLYVVGLAILTALLLVVGFisiApattNTAWaTGSMLLVY-TFFYdSTVGPVCYSLVAEIPSTRLRIKTVALARNLYNCFSILNGVIIPYM 462
                 778************999999555556454265655566444444444.4444599*********************************9987777666 PP

       MFS_1 145 a..sslgWravfyilaivsllafvlfllllpeepperkrkspkee 187
                 +  ++++Wr+   ++ + ++l+  ++++ +++ p +++r   + +
  EEA19648.1 463 LnvDAWNWRGKAGFFWGGLALL--CWVWAYWRVPEPKGRTYAEMD 505
                 6367777777644444444444..666999999999988776666 PP

>> MFS_2  MFS/sugar transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   2.7     6e-07    0.0015     266     337 ..     106     175 ..      94     184 .. 0.83
   2 ?   -2.5   0.4      0.53   1.4e+03     262     316 ..     191     248 ..     186     249 .. 0.69
   3 !   12.5   7.0   1.5e-05     0.039     220     338 ..     300     427 ..     274     432 .. 0.69

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 6e-07
       MFS_2 266 lvvtisallgiplwqplakrlgkkntyllgalltivllvlvlllqpsnlllflvllviagfgvgvaallpws 337
                  ++  +++lg++    +  r+g ++t++ ++ ++ v+++++l++ ++n+ ++lv  ++ g+++gv ++l   
  EEA19648.1 106 NAMNCGQILGLFANGIISERFGYRKTMMYSL-VATVGFIFILFF-AQNVQTLLVGEILMGIPLGVYQTLSVT 175
                 45678999**************999988875.566899999999.9*******************9998765 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.53
       MFS_2 262 svfllvvtisallgiplwqplakrlgkknt...yllgalltivllvlvlllqpsnlll 316
                 +++ l+ +i++l+++ + + la r +  ++   +++  +  i+++++vll+++s ++l
  EEA19648.1 191 TYVNLCWVIGQLVASGVLKGLANRADQWAYripFAVQWVWPIPIFIGVLLAPESPWWL 248
                 6778888899999999999999888854331124444556789999999996666655 PP

  == domain 3  score: 12.5 bits;  conditional E-value: 1.5e-05
       MFS_2 220 vfrnraflillllfllaalalgvlnglllYyltyvlgngsaas...vfllvvtisallgiplwqplakrlgkkntyllgalltivllvlvlll.....q 310
                 +fr   + +  +++l+ a+  +++ gl++Y   ++ ++g  +s   +++l+ ++ ++ g+++ + l  r+g++++y++g++++ +ll++v ++     +
  EEA19648.1 300 CFRGMDLYRTEISCLIWAAQNLCGSGLMAYSTVFYQRAGLPVSqsfNMSLAQYAIGFFGTVFSWFLMMRFGRRTLYVVGLAILTALLLVVGFIsiapaT 398
                 555555555556666666666666666666666665544333311145566688899**********************99999999999888899987 PP

       MFS_2 311 psnlllflvllviagfgvgv.aallpwsm 338
                 ++  +++  +l+++ f++ +  + + +s+
  EEA19648.1 399 TNTAWATGSMLLVYTFFYDStVGPVCYSL 427
                 77777777777777777765345555555 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   3.6   5.4e-06     0.014     272     362 ..     111     200 ..      29     211 .. 0.81
   2 !    7.2   0.7   0.00075       1.9      16      86 ..     324     393 ..     322     435 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 5.4e-06
  MFS_1_like 272 aeiplfffaeklleklGhvklliiallayilrfllyaiienawlvlpievLhgisfgllwaaaveyvskiapksleatgqgllsglyfglG 362
                 ++i  +f +  + e++G +k ++ +l+a++   +++ + +n+  +l+ e+L gi +g++    v+y+s++ p  l+a +   ++ l++ +G
  EEA19648.1 111 GQILGLFANGIISERFGYRKTMMYSLVATVGFIFILFFAQNVQTLLVGEILMGIPLGVYQTLSVTYASEVCPVALRAYLT-TYVNLCWVIG 200
                 5788899999*****************998877777788*********************************99998654.3444555555 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.00075
  MFS_1_like  16 gsllPYltiylkskglkaseigiitlilpltsilsppiwgvlaDrfgkrkk.vvilslllsavlflsllfip 86 
                 ++l+ Y t++ +  gl +s++  ++l+  ++ +++  +  +l  rfg+r+  vv l++l +++l+  + fi+
  EEA19648.1 324 SGLMAYSTVFYQRAGLPVSQSFNMSLAQYAIGFFGTVFSWFLMMRFGRRTLyVVGLAILTALLLV--VGFIS 393
                 67899******************************************998743333333333333..34443 PP

>> OppC_N  N-terminal TM domain of oligopeptide transport permease C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.4     0.043   1.1e+02      10      33 ..     126     149 ..     121     157 .. 0.62
   2 ?    9.6   0.6   0.00034      0.86       9      32 ..     368     391 ..     361     427 .. 0.81
   3 ?   -3.2   0.0       3.4   8.7e+03      29      39 ..     451     461 ..     447     466 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.043
      OppC_N  10 FkrNklAvvglvilllllliaifa 33 
                 F + k+ + +lv  + +++i +fa
  EEA19648.1 126 FGYRKTMMYSLVATVGFIFILFFA 149
                 555555555555555555555554 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00034
      OppC_N   9 rFkrNklAvvglvilllllliaif 32 
                 rF r  l vvgl+il +lll++ f
  EEA19648.1 368 RFGRRTLYVVGLAILTALLLVVGF 391
                 8999999*************9744 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 3.4
      OppC_N  29 iaifaPliaPy 39 
                 ++i++ +i+Py
  EEA19648.1 451 FSILNGVIIPY 461
                 79999999998 PP

>> YtpI  YtpI-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.3      0.35   9.1e+02      40      54 ..     143     158 ..     120     169 .. 0.69
   2 ?    9.7   3.0   0.00037      0.94      10      74 ..     326     395 ..     321     402 .. 0.79

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.35
        YtpI  40 lflilfgin.qlllle 54 
                 +f+++f+ n q+ll +
  EEA19648.1 143 IFILFFAQNvQTLLVG 158
                 5666666666666544 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.00037
        YtpI  10 lyvyykvkafrtkdplekkllsakasialGlflilfginqllllestvalvvg.....avflvlGlanlf 74 
                 l+ y  v + r+  p+ + + ++ a+ a+G+f ++f+  +++ ++    +vvg     a++lv+G++++ 
  EEA19648.1 326 LMAYSTVFYQRAGLPVSQSFNMSLAQYAIGFFGTVFSWFLMMRFGRRTLYVVGlailtALLLVVGFISIA 395
                 5678889999*****************************8887766666666522222678889988876 PP

>> DUF4131  Domain of unknown function (DUF4131)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.2       1.1   2.9e+03      35      52 ..     136     153 ..     111     175 .. 0.59
   2 ?    2.0   3.5     0.056   1.4e+02       5      40 ..     374     410 ..     346     419 .. 0.56
   3 ?   10.8   0.2   0.00011      0.29      26      56 ..     466     498 ..     441     512 .. 0.80

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 1.1
     DUF4131  35 llllllllallgfalrap 52 
                 l++ + +++ l+fa+ ++
  EEA19648.1 136 LVATVGFIFILFFAQNVQ 153
                 333344444444444444 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.056
     DUF4131   5 lalvllalllllllllllllrr.rprrrvllllllll 40 
                 l++v la+l +lll+ ++++   +++++ +++ ++ll
  EEA19648.1 374 LYVVGLAILTALLLVVGFISIApATTNTAWATGSMLL 410
                 3445555555555555555444555555555555555 PP

  == domain 3  score: 10.8 bits;  conditional E-value: 0.00011
     DUF4131  26 r..rprrrvllllllllllallgfalrapqpna 56 
                 +  ++r +  ++++ l+ll+++++++r+p+p  
  EEA19648.1 466 DawNWRGKAGFFWGGLALLCWVWAYWRVPEPKG 498
                 1558999999*******************9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (536 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       857  (0.0477997); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.45
# Mc/sec: 3578.82
//
Query:       EEA19649.1  [L=606]
Description: dextranase precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.9e-88  292.7   0.6    9.9e-88  292.7   0.6    2.2  2  Glyco_hydro_49N  Glycosyl hydrolase family 49 N-terminal Ig-l
    1.2e-40  138.1   0.6    2.6e-40  137.1   0.6    1.6  1  Glyco_hydro_49   Glycosyl hydrolase family 49
    2.2e-17   63.1   5.2      6e-17   61.6   5.2    1.9  1  B_solenoid_dext  Beta solenoid repeat from Dextranase
      1e-13   51.1   0.6      1e-13   51.1   0.6    1.8  2  IPU_b_solenoid   Isopullulanase beta-solenoid repeat


Domain annotation for each model (and alignments):
>> Glyco_hydro_49N  Glycosyl hydrolase family 49 N-terminal Ig-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  292.7   0.6   2.2e-91   9.9e-88       1     188 []      35     233 ..      35     233 .. 0.99
   2 ?    1.5   0.6     0.045     2e+02       6      18 ..     348     360 ..     344     368 .. 0.82

  Alignments for each domain:
  == domain 1  score: 292.7 bits;  conditional E-value: 2.2e-91
                      ------BSSSEE----TTEEE-SSS---TT-EEE-SSEEEEEEETTTTSS-EEE--EEE-GGGGTGS-............-TT--GCGCCCHHH CS
  Glyco_hydro_49N   1 qaavtasgaelltWWhdngeintqtPvqdgnvrrsslysvqvataaaseklydsfvylsiPrsGkgki............dyteedgiefsssa 82 
                      ++++t++g++++tWWh++geintqtPvq+gnvr+s++ysvqv++a+a +++ydsfvy+siPr+G+g+i            d  ++dgi++++++
       EEA19649.1  35 TTNNTHCGTDFRTWWHNSGEINTQTPVQPGNVRQSHKYSVQVSLAGA-NTFYDSFVYESIPRNGNGRIyaptdlpgsntlDPGVDDGISIEPGI 127
                      589********************************************.9*******************************99************ PP

                      T-EEEEEEEEESS-EEEEEEECTTTS---GGGEEEESCCC--EEEE-CTTEEEEEE---TT-EEEEEEEGGGEEEECCTSSSEESSTCEEEEEE CS
  Glyco_hydro_49N  83 nltmaWssfeyskdvtvkvslrdGssissaddvvirPsslnfevrlvdadtvrikvPysaaGyrfsvefeddlytllndGdeevasGdraihte 176
                      +l+maWs+feys+dv++k+++ dGss++s++dvvirP+s++++++++ +++++i++P++a+G++fsvef++dlyt+l+dG+e+v+sG++a+++e
       EEA19649.1 128 GLNMAWSQFEYSQDVDIKILAIDGSSLGSPSDVVIRPVSISYAISQSSDGGIVIRIPADANGRKFSVEFKNDLYTFLSDGNEYVTSGGTAVGVE 221
                      ********************************************************************************************** PP

                      ESEEEEEEEEE- CS
  Glyco_hydro_49N 177 PrnallifaePf 188
                      P+nal+ifa+Pf
       EEA19649.1 222 PTNALVIFASPF 233
                      ***********7 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.045
                      -BSSSEE----TT CS
  Glyco_hydro_49N   6 asgaelltWWhdn 18 
                       + + l+ WWh+n
       EEA19649.1 348 SDTTSLRMWWHNN 360
                      567899******8 PP

>> Glyco_hydro_49  Glycosyl hydrolase family 49
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.1   0.6   5.8e-44   2.6e-40       1     117 [.     496     605 ..     496     606 .] 0.98

  Alignments for each domain:
  == domain 1  score: 137.1 bits;  conditional E-value: 5.8e-44
                     SST-BBEEEEEEEEEEEEEEEEECCE-ECEEE--SEEEEEEEEEEEEECEET-CG...CSTT-EEE---CCTTT..B..EEEEEEEEEEETTEE- CS
  Glyco_hydro_49   1 gssttadsnktvknltlenvaveGltnalvRiyalqnlenisiknvnieafegLe...igtqeshlkrysdlanekvidstglklenytvGgqki 92 
                     +s++++ds k++ +lt++nv++eGl+++lvRi++lqn++n+++knv+++  +gL+   igt+es+++++s+l       ++gl+++n+t+Ggq++
      EEA19649.1 496 ASGMSPDSSKSI-SLTVSNVVCEGLCPSLVRITPLQNYKNVVVKNVAFP--DGLQtnsIGTGESIIPAASGL-------TMGLDISNWTIGGQQV 580
                     699*********.************************************..99998889*************.......9*************** PP

                     -TTT-STTTTT-EEE-GGGCCCEEE CS
  Glyco_hydro_49  93 taenfsaaslGrldvDgeywgewna 117
                     t++nf+ +slG++++Dg+ywgew++
      EEA19649.1 581 TMQNFQSNSLGQFNIDGSYWGEWQI 605
                     ***********************98 PP

>> B_solenoid_dext  Beta solenoid repeat from Dextranase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.6   5.2   1.3e-20     6e-17       1      33 []     378     409 ..     378     409 .. 0.98

  Alignments for each domain:
  == domain 1  score: 61.6 bits;  conditional E-value: 1.3e-20
  B_solenoid_dext   1 PFNsMDfyGdsdnisvevaDYKQVGaFfgQTDG 33 
                      PFN+MDf+G+s +is++++DYKQVGaFf+QTDG
       EEA19649.1 378 PFNTMDFNGNS-DISSQINDYKQVGAFFFQTDG 409
                      9********86.********************9 PP

>> IPU_b_solenoid  Isopullulanase beta-solenoid repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.1   0.6   2.2e-17     1e-13       1      33 []     445     477 ..     445     477 .. 1.00
   2 ?   -3.0   0.3       1.8   8.1e+03      17      26 ..     531     540 ..     530     541 .. 0.85

  Alignments for each domain:
  == domain 1  score: 51.1 bits;  conditional E-value: 2.2e-17
  IPU_b_solenoid   1 WKtntAPivqfGWysRnltNitVdhVdvIHsrY 33 
                     WK  + Pi+q+GW+sR+++ +t+d  +vIH+rY
      EEA19649.1 445 WKCHNDPIIQMGWTSRDISGVTIDTLNVIHTRY 477
                     ********************************9 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.8
  IPU_b_solenoid  17 nltNitVdhV 26 
                     n +N+ V +V
      EEA19649.1 531 NYKNVVVKNV 540
                     789**99998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (606 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       345  (0.0192426); expected 358.6 (0.02)
Passed bias filter:                      267  (0.0148921); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.59u 0.27s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 4000.72
//
Query:       EEA19650.1  [L=278]
Description: hypothetical protein PMAA_004290 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
     0.0025   18.1   7.4     0.0025   18.1   7.4    2.5  3  DUF3446       Early growth response N-terminal domain
  ------ inclusion threshold ------
        1.2    8.7  10.2      0.093   12.3   5.6    1.4  2  FAM220        FAM220 family
        1.3    9.9   6.8        7.5    7.4   4.2    2.4  2  Chorion_2     Chorion family 2


Domain annotation for each model (and alignments):
>> DUF3446  Early growth response N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.1       1.2   7.2e+03      41      44 ..      34      37 ..      14      48 .. 0.55
   2 !   18.1   7.4   4.2e-07    0.0025      20      60 ..     109     153 ..      92     180 .. 0.59
   3 ?   -0.7   0.2      0.31   1.8e+03      38      48 ..     251     261 ..     242     272 .. 0.50

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 1.2
     DUF3446 41 ssss 44
                s+s 
  EEA19650.1 34 STSD 37
                1111 PP

  == domain 2  score: 18.1 bits;  conditional E-value: 4.2e-07
     DUF3446  20 llslvsglvgvanppss......psssssssssssssssspslscsv 60 
                 ll +  gl ++ +  s       ++sssssssssssssss++ls+++
  EEA19650.1 109 LLAIKIGLCTLPA--SKrnlvvsSPSSSSSSSSSSSSSSSSNLSSAT 153
                 7777777776632..22334442333444444555555555554433 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 0.31
     DUF3446  38 sssssssssss 48 
                 s+ s s++ss+
  EEA19650.1 251 SPFSDSTASSP 261
                 22222222222 PP

>> FAM220  FAM220 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.1      0.95   5.7e+03      26      75 ..      17      33 ..       8      43 .. 0.45
   2 ?   12.3   5.6   1.6e-05     0.093      93     166 ..     133     208 ..     115     213 .. 0.66

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 0.95
      FAM220 26 slklttklkkrsqkesvspsdapswtaqsvldsnkrsrakeakslekksa 75
                +                                 +++ ++++ks+e +s 
  EEA19650.1 17 N---------------------------------NNNNNNNNKSIEDRSL 33
                2.................................2333333333333332 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 1.6e-05
      FAM220  93 lkessrrssasasssskavslssapk.........kenfdsvlcyideavvsdWLeranksvnelrewlhkgenfvqFahfWl 166
                   +ss  ss+s+sss+ + +                 n ds    + e++vs+W +r+ +++++ ++ +   ++   F +fW+
  EEA19650.1 133 SSSSSSSSSSSSSSSNLSSA-----TflysntaaiWYNRDSKQIWVAENTVSNWYARESETTQQEQQRCSDPKK--VFEEFWM 208
                 22222222222222222111.....1233344556778888888999**********************88888..9*****8 PP

>> Chorion_2  Chorion family 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   4.2    0.0013       7.5      45      65 ..     128     148 ..     106     170 .. 0.68
   2 ?    2.4   0.0     0.049   2.9e+02      26      59 ..     240     264 ..     214     274 .. 0.64

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0013
   Chorion_2  45 dsspsdseaislaklalAape 65 
                 +ssps+s+++s +++++++++
  EEA19650.1 128 VSSPSSSSSSSSSSSSSSSSN 148
                 444554444444444444433 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.049
   Chorion_2  26 rgrGnrgYgrsvesgrrygdsspsdseaislakl 59 
                  + Gn           + g+s+ sds a+s a  
  EEA19650.1 240 DRDGNS---------NGRGSSPFSDSTASSPAEN 264
                 444433.........3445666777777777755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (278 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1002  (0.0558871); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2053.93
//
Query:       EEA19651.1  [L=781]
Description: fungal specific transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.4e-08   34.0   7.9    3.9e-08   33.3   7.9    1.3  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
    3.5e-05   23.0   0.2    9.1e-05   21.6   0.2    1.8  1  Fungal_trans  Fungal specific transcription factor domain
  ------ inclusion threshold ------
          1   10.2   7.5       0.16   12.8   1.3    2.5  2  Apc15p        Apc15p protein


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.3   7.9   6.5e-12   3.9e-08       1      37 [.      55      92 ..      55      95 .. 0.87

  Alignments for each domain:
  == domain 1  score: 33.3 bits;  conditional E-value: 6.5e-12
                SS-HHHHHCT---STSSSS..-HHHHHCTHHHCCCCTCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPa..CsnCkklnleCtfysess 37
                +aC++C+++Kv+Cd+k +   C++C++ +l+C+  ++s 
  EEA19651.1 55 RACTECKRHKVRCDMKVGDqiCQRCQRMGLQCV-VNKSL 92
                69*************777777************.66655 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.6   0.2   1.5e-08   9.1e-05     112     179 ..     338     399 ..     268     413 .. 0.87

  Alignments for each domain:
  == domain 1  score: 21.6 bits;  conditional E-value: 1.5e-08
  Fungal_trans 112 lherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrpplldds 179
                     ++++g avr+a++  Lh++          + ++e + +   lw+  ++l+ ++++ +Grpp+++++
    EEA19651.1 338 VSWKLSGYAVRIATERNLHQCYRKAI-----QGSPE-HREQTQLWYILYILEHHFSIAYGRPPIIHED 399
                   5799*****************99988.....45666.44449*********************77765 PP

>> Apc15p  Apc15p protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.6      0.34     2e+03      39      72 ..     155     188 ..     131     215 .. 0.52
   2 ?   12.8   1.3   2.7e-05      0.16      27      83 ..     700     758 ..     692     764 .. 0.72

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.34
      Apc15p  39 kakernedqkksrrsgyapplsaynaieespyyp 72 
                 +++++   q++ ++++  p++      e+s y p
  EEA19651.1 155 TEEHTAPSQSNGINHSRRPSSGYRTHREQSHYSP 188
                 2233334444444444333333333333333333 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 2.7e-05
      Apc15p  27 rnkklnngnatn...kakernedqkksrrsgyapplsaynaieespyyprggkldelrme 83 
                 r +++ n+ ++n   +a+++n+++ +++++ + p+++a   + ++ +++ +g+ld ++ +
  EEA19651.1 700 RGSNNTNTSNNNihnDANHNNHNNHNHNNNTFPPSSTADLSAKSQVGLS-EGSLDPMMTD 758
                 3333322222223347788999999999999999999999999999888.9999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (781 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       768  (0.0428356); expected 358.6 (0.02)
Passed bias filter:                      482  (0.0268838); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.69u 0.28s 00:00:00.97 Elapsed: 00:00:00.47
# Mc/sec: 5029.40
//
Query:       EEA19652.1  [L=411]
Description: Flap endonuclease Rad27, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      3e-31  107.6   1.2    1.4e-30  105.5   0.1    2.3  2  XPG_I       XPG I-region
    2.8e-21   75.9   0.1    1.8e-20   73.3   0.0    2.3  2  XPG_N       XPG N-terminal domain
    3.7e-06   27.5   0.5    1.8e-05   25.2   0.0    2.3  2  5_3_exonuc  5'-3' exonuclease, C-terminal SAM fold
  ------ inclusion threshold ------
       0.04   14.5   0.0       0.11   13.2   0.0    1.7  1  HHH_5       Helix-hairpin-helix domain
       0.09   12.9   0.0       0.24   11.6   0.0    1.6  1  HHH_2       Helix-hairpin-helix motif


Domain annotation for each model (and alignments):
>> XPG_I  XPG I-region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  105.5   0.1   3.9e-34   1.4e-30       1      94 []     162     249 ..     162     249 .. 0.97
   2 ?    0.4   0.2      0.24   8.6e+02      41      74 ..     345     382 ..     326     403 .. 0.59

  Alignments for each domain:
  == domain 1  score: 105.5 bits;  conditional E-value: 3.9e-34
                 HHHT--EEE-SS-HHHHHHHHHHTTSSSEEE-SSSHHHHTT-SEEEESTT.ECECTT..EEECEEEEEEHHHHHHHHT--HHHHHHHHHHHCET CS
       XPG_I   1 klmgipyvvApgEAEAqcayLqkkglvdaviseDsDlllFGapkvlrnlskkkskkkkekekkkvevidlekvlkelgltreqlidlaillgcD 94 
                 klmg+py++Ap+EAEAqca L+++g+v+a++seD+D+l+F ap +lr+l+  +s+++    k+++ +i+l+k+l+ lg++++q+idl+illgcD
  EEA19652.1 162 KLMGVPYIDAPTEAEAQCAVLARAGKVYAAASEDMDTLCFEAPILLRHLT--FSEQR----KEPILEIHLDKALEGLGMDMAQFIDLCILLGCD 249
                 68***********************************************9..87777....889*****************************9 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.24
                 T-SEEEESTT.ECECTT............EEECEEEEEEHHHHH CS
       XPG_I  41 Gapkvlrnlskkkskkk..........kekekkkvevidlekvl 74 
                 Ga ++ +nl+ + ++++          +       e+ ++++  
  EEA19652.1 345 GAARLAKNLK-TAQQSRlegffkpvakT-----DAEKASMKRKH 382
                 7888888886.33333356777555542.....33333332222 PP

>> XPG_N  XPG N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.3   0.0     5e-24   1.8e-20       6     101 .]      14     123 ..      12     123 .. 0.88
   2 ?   -0.8   0.1      0.62   2.2e+03      74      97 ..     366     389 ..     344     399 .. 0.57

  Alignments for each domain:
  == domain 1  score: 73.3 bits;  conditional E-value: 5e-24
                 HHHHHHHH-..GEEEEEGGGGTTEEEEE........EHHHHHHHHHHHSE.ETTEE-BS.....-HHHHHHHHHHHHHHHTTEEEEEEE--S--GGGHH CS
       XPG_N   6 Llkllkeva..airsvsiealegkklai........Daslwlyrfliavreqlgnalen.....tshlmglfsrllrlldfgikPifVFdgkapdlkke 89 
                 L ++++e a  a++  +i++ +g+k+ai         +s+++y fliavr+ +g++l++     tshlmg+f+r+lr++d+gikP++VFdg +p++k +
  EEA19652.1  14 LYQVISENApdAVKTGEIKNHFGRKVAIvriniaeyRISMSIYSFLIAVRS-DGQQLMSeagetTSHLMGMFYRTLRIVDNGIKPLYVFDGAPPKMKGG 111
                 778999999999*************99855544444479***********5.556665558999*********************************** PP

                 HHHHHHHHHHHH CS
       XPG_N  90 elekrserrqea 101
                 el+krs+r+ ea
  EEA19652.1 112 ELAKRSARKREA 123
                 ********9875 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.62
                 EEEEEE--S--GGGHHHHHHHHHH CS
       XPG_N  74 kPifVFdgkapdlkkeelekrser 97 
                 kP+   d ++ ++k++  ek +e+
  EEA19652.1 366 KPVAKTDAEKASMKRKHDEKIEEQ 389
                 344444444555555444444443 PP

>> 5_3_exonuc  5'-3' exonuclease, C-terminal SAM fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   0.0     5e-09   1.8e-05       5      53 ..     238     284 ..     235     300 .. 0.86
   2 ?   -1.9   0.7       1.5   5.4e+03      54      65 ..     380     391 ..     347     403 .. 0.54

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 5e-09
  5_3_exonuc   5 qiidlkaLvGDssDnipGvpgiGektAakLlkeygsleeilenldelke 53 
                 q+idl  L G   D ++ +p++G+ tA kL++e+gsle+++e++++  +
  EEA19652.1 238 QFIDLCILLG--CDYLEPIPKVGPNTALKLIREHGSLEKVVEAIENDPK 284
                 8899999999..7999**************************9985332 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 1.5
  5_3_exonuc  54 kklkekLeenke 65 
                  k  ek+ee+k+
  EEA19652.1 380 RKHDEKIEEQKK 391
                 233444444443 PP

>> HHH_5  Helix-hairpin-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0     3e-05      0.11       4      34 ..     251     280 ..     249     289 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 3e-05
                 HHTSTT--HHHHHHHHTTT--SHHHHHHS-H CS
       HHH_5   4 LlsvsGiGpktAlallsaGiesvedlaaadv 34 
                 L  ++++Gp tAl+l++   +s+e++++a +
  EEA19652.1 251 LEPIPKVGPNTALKLIRE-HGSLEKVVEAIE 280
                 5569**********9999.788888887743 PP

>> HHH_2  Helix-hairpin-helix motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   6.6e-05      0.24       8      33 ..     254     279 ..     252     282 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 6.6e-05
       HHH_2   8 IrhVGektAklLakrFksldaLkkas 33 
                 I++VG +tA +L ++ +sl++  +a 
  EEA19652.1 254 IPKVGPNTALKLIREHGSLEKVVEAI 279
                 9********************99885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (411 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1825  (0.10179); expected 358.6 (0.02)
Passed bias filter:                      821  (0.0457917); expected 358.6 (0.02)
Passed Vit filter:                        75  (0.00418317); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.64u 0.29s 00:00:00.93 Elapsed: 00:00:00.47
# Mc/sec: 2652.90
//
Query:       EEA19653.1  [L=194]
Description: histone H1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.9e-30  103.5   0.2    5.9e-30  103.5   0.2    1.9  3  Linker_histone  linker histone H1 and H5 family


Domain annotation for each model (and alignments):
>> Linker_histone  linker histone H1 and H5 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.5   0.2   3.3e-34   5.9e-30       1      74 []      19      92 ..      19      92 .. 0.98
   2 ?   -3.6   0.3      0.84   1.5e+04      26      31 ..     118     123 ..     114     136 .. 0.45
   3 ?   -2.2   0.1      0.31   5.6e+03      43      52 ..     174     183 ..     157     189 .. 0.50

  Alignments for each domain:
  == domain 1  score: 103.5 bits;  conditional E-value: 3.3e-34
  Linker_histone  1 hpsykdMikeAIkalkerkGsSrqaIkkyikakykvv..dvskfksllkkalkkgvekgelvqpkgkGasGsfKLa 74
                    h sy+dMik+AI +lk+r+GsSrq+Ikky+++++k++  ++++f+ +++ka+k+gvekge+ qpk  G+sG++KLa
      EEA19653.1 19 HASYRDMIKDAIVSLKDRNGSSRQSIKKYVQSNNKITvvSPAAFDAQFNKAIKAGVEKGEFSQPK--GPSGPVKLA 92
                    89**********************************99999************************..*******96 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 0.84
  Linker_histone  26 Ikkyik 31 
                     +kk  +
      EEA19653.1 118 VKKATA 123
                     222222 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 0.31
  Linker_histone  43 ksllkkalkk 52 
                     k+  k a+kk
      EEA19653.1 174 KTTAKPAVKK 183
                     2333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (194 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1296  (0.0722851); expected 358.6 (0.02)
Passed bias filter:                      449  (0.0250432); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.29s 00:00:00.85 Elapsed: 00:00:00.48
# Mc/sec: 1223.83
//
Query:       EEA19654.1  [L=877]
Description: multicopy suppressor of stt4 mutation [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     7e-101  337.0   0.0   1.4e-100  336.1   0.0    1.5  1  PIP5K     Phosphatidylinositol-4-phosphate 5-Kinase


Domain annotation for each model (and alignments):
>> PIP5K  Phosphatidylinositol-4-phosphate 5-Kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  336.1   0.0  7.8e-105  1.4e-100       2     272 ..     436     749 ..     435     751 .. 0.97

  Alignments for each domain:
  == domain 1  score: 336.1 bits;  conditional E-value: 7.8e-105
                 SS-EEEE----SSS--EEEETTSSEEEEEE-HHHHHHHHHHHHHHHHHHTT-TT--S--EEEEEEEE.ETTEEEEEEEEE-SS-TTS--SEEEEE-S-- CS
       PIP5K   2 ksalkelsseGkSgsffylteDkkfiiKtitksevkflrkllpeYyehvkenpnsLltrfyglhrvklkggkkvrfvVmenlfptdkeiheryDLKGst 100
                 k++l+el+s+GkSgsffy+++D+k+iiKti++se+k+lrk+lp+Yy+h+++npn+L+++fyglhrvk+++g+k++fvVm+nlfp++++ih+++DLKGst
  EEA19654.1 436 KYILSELGSPGKSGSFFYFSRDYKYIIKTIHHSEHKLLRKILPDYYKHIESNPNTLISQFYGLHRVKMAYGRKIHFVVMNNLFPPHRDIHQTFDLKGST 534
                 689************************************************************************************************ PP

                 TT-S--HHHH.TSSS-EEEHHHHHHHST.EEE-HHHHHHHHHHHHHHHHHHHHTTB-S-EEEEEEEB---------------------------..... CS
       PIP5K 101 vgReakkkee.ekkektlkDlDliekkeklklgkekreelleqlekDvefLeslnimDYSLLlGihnsekeekeekkesessssekesekseee..... 193
                 vgR  ++++  ++ + t+kDl++ ++ ++l+ g+ k+e +++ql++Dv++L++l+imDYSLL+Gih+  + ++e+ ++++ + +++  +++++      
  EEA19654.1 535 VGRDLREENLeKNPRATMKDLNWLRRGRHLEAGPMKKEVFMAQLRRDVRLLQRLKIMDYSLLVGIHDLGRGNEEKLRDKTLQVFQPGGDRDDDPstllt 633
                 ******76662555678******************************************************************9999888888799*** PP

                 .....................................-----------------SEEEEESSSSEEEEEEEEE----B--------------------- CS
       PIP5K 194 .....................................aseeeeeseeeedeegekakeensedgkevyylgiIDiLqkynlkKklehalkslkkdkksi 255
                                                        +e+++  +++d++g +a++en ++g+e+yylgiID+L+ y++ Kk+eh++k+l++++++i
  EEA19654.1 634 rtpsklenarkarelrltlkrerpvpiqqtaakmpdeILDERKNLVFYSDDGGFRATHENGQPGEEIYYLGIIDCLTPYGIVKKAEHFWKGLSNNRTQI 732
                 ***********************************99899999******************************************************** PP

                 -TTHHHHHHHHHHHHHH CS
       PIP5K 256 savpPkeYaeRFlkfie 272
                 s +pP++Y eRF++f+e
  EEA19654.1 733 SPIPPEQYGERFINFTE 749
                 ***************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (877 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       609  (0.0339673); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.72u 0.29s 00:00:01.01 Elapsed: 00:00:00.47
# Mc/sec: 5611.41
//
Query:       EEA19655.1  [L=403]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.5e-07   30.0   0.4    5.2e-07   29.0   0.4    1.6  1  SKG6      Transmembrane alpha-helix domain
  ------ inclusion threshold ------
      0.025   14.5   0.1      0.025   14.5   0.1    2.5  3  TMEM154   TMEM154 protein family
      0.085   13.2   2.0       0.58   10.5   0.2    2.4  2  Granulin  Granulin
       0.12   12.3   0.1       0.22   11.5   0.1    1.3  1  LcrG      LcrG protein


Domain annotation for each model (and alignments):
>> SKG6  Transmembrane alpha-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.0   0.4   1.2e-10   5.2e-07       3      37 ..     314     348 ..     312     349 .. 0.90

  Alignments for each domain:
  == domain 1  score: 29.0 bits;  conditional E-value: 1.2e-10
        SKG6   3 dssnsntvaIavaVaVPVaViiivLlailifvrRR 37 
                 ++++++t++Ia+ V++P ++++i+   + +++rRR
  EEA19655.1 314 SNNHHKTTTIAISVVIPCVAVLIAASLGWLWYRRR 348
                 579**************************966666 PP

>> TMEM154  TMEM154 protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   2.8       2.8   1.2e+04      28      28 ..      32      32 ..       3      64 .. 0.49
   2 ?   -1.8   0.3      0.59   2.6e+03      23      46 ..     238     260 ..     212     272 .. 0.51
   3 ?   14.5   0.1   5.5e-06     0.025      13      98 ..     281     359 ..     270     396 .. 0.67

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 2.8
     TMEM154 28 a 28
                +
  EEA19655.1 32 T 32
                1 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.59
     TMEM154  23 datsaasteseslkqeeakeslss 46 
                 ++t++ s+ s++l ++e  ++++ 
  EEA19655.1 238 PTTVTLSS-SDTLLSTEVTATTNL 260
                 33333333.444443444444433 PP

  == domain 3  score: 14.5 bits;  conditional E-value: 5.5e-06
     TMEM154  13 etatleeesadatsaasteseslkqeeakeslssaelsnesdqlelvlmiiiPlvllillllvviiliqkkkrkrsKddekseaes 98 
                 +tatl++ s+ + +  st  ++++  ++ +s ss   +n+     + + ++iP v++++   ++ +    ++r+ +K++  s a++
  EEA19655.1 281 STATLSSSSSFS-TLSSTSLPTYP--TSTDSGSSSGSNNHHKTTTIAISVVIPCVAVLIAASLGWLW---YRRRARKQQ-PSTAYQ 359
                 333333333332.33344355555..56677777777888888899999******987766666554...466666666.344444 PP

>> Granulin  Granulin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.1     0.092   4.1e+02      28      38 ..     148     160 ..     146     162 .. 0.79
   2 ?   10.5   0.2   0.00013      0.58      26      35 ..     189     198 ..     180     205 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.092
                 SSTTS..EEECTT CS
    Granulin  28 CPegy..kCdleg 38 
                 CP+gy   C +++
  EEA19655.1 148 CPAGYstACAAQA 160
                 *****88897765 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00013
                 TSSSTTSEEE CS
    Granulin  26 hCCPegykCd 35 
                  CCP gy+C 
  EEA19655.1 189 GCCPTGYQCT 198
                 6********6 PP

>> LcrG  LcrG protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.1   4.9e-05      0.22      64      88 ..     347     371 ..     341     372 .. 0.95

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 4.9e-05
        LcrG  64 kRrRsrqpqqgeqGkRrrrPtmmRG 88 
                 +R R++qp+ ++q  +   Pt mRG
  EEA19655.1 347 RRARKQQPSTAYQAVKSSEPTEMRG 371
                 799*********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (403 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       941  (0.0524848); expected 358.6 (0.02)
Passed bias filter:                      453  (0.0252663); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.57u 0.24s 00:00:00.81 Elapsed: 00:00:00.42
# Mc/sec: 2852.90
//
Query:       EEA19656.1  [L=673]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.016   15.9   0.7      0.046   14.4   0.7    1.7  1  UBA2_C    SUMO-activating enzyme subunit 2 C-terminus


Domain annotation for each model (and alignments):
>> UBA2_C  SUMO-activating enzyme subunit 2 C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.7   2.6e-06     0.046      33      58 ..      81     106 ..      68     116 .. 0.71

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 2.6e-06
      UBA2_C  33 tkaaaeedDvliVdsdeEesassada 58 
                 +k  +++d ++i+dsd+Ee a +++ 
  EEA19656.1  81 SKPHNNDDSIMIIDSDDEEPAPASSN 106
                 334456666*********88877764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (673 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       383  (0.021362); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.26s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 4545.45
//
Query:       EEA19657.1  [L=2071]
Description: 20S cyclosome subunit (APC1/BimE), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.4e-31  107.8   0.6    5.4e-31  107.8   0.6    2.2  2  ANAPC1    Anaphase-promoting complex subunit 1
  ------ inclusion threshold ------
       0.02   15.3   9.1       0.96   10.0   0.0    4.7  4  PC_rep    Proteasome/cyclosome repeat


Domain annotation for each model (and alignments):
>> ANAPC1  Anaphase-promoting complex subunit 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  107.8   0.6     6e-35   5.4e-31       1     129 [.     144     262 ..     144     263 .. 0.81
   2 ?   -3.0   0.1       1.2     1e+04      78     119 ..     543     586 ..     521     596 .. 0.53

  Alignments for each domain:
  == domain 1  score: 107.8 bits;  conditional E-value: 6e-35
      ANAPC1   1 aLvVllkdqahiyflsGeshtvpLpFevasvfplpkGlllqRkpeedqapprslrnpsappnsfldsssplltsssqtssqkttfstesrgspkrlslt 99 
                 aLvV+lk+qahi+fl+G+sh+vpLpFev+svf+ p+Gl++qR++  +   + s++ p appnsfl+ s+      + ++s++++    srg+  rls+t
  EEA19657.1 144 ALVVVLKTQAHIFFLAGNSHVVPLPFEVDSVFASPRGLIFQRQIP-E---APSTSLPGAPPNSFLSHSFT-----DSRRSDNFRS---SRGRDDRLSST 230
                 7*******************************************6.3...478999*********33332.....3344443333...88888888887 PP

      ANAPC1 100 lsstles..kkdsslPslfsLtdPlsevglvv 129
                  + ++ +  ++d ++P+ fsLtdP+se+g+v 
  EEA19657.1 231 EQLSRLQkkNDDLDMPRTFSLTDPHSEMGHVI 262
                 77776664344444***************996 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.2
      ANAPC1  78 tssqkttfstesrgspkrlsltlsstleskkdsslP..slfsLt 119
                  s+ +++fs  +r++pk+   tl +  + ++++s +    ++L 
  EEA19657.1 543 LSTGSFSFSELKRTRPKPKAFTLRPNESVHQKTSTSahLALCLL 586
                 44455555555666666666555555444444444411344555 PP

>> PC_rep  Proteasome/cyclosome repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.1     0.011     1e+02       2      15 ..    1419    1432 ..    1418    1441 .. 0.79
   2 ?    4.5   0.1    0.0061        55       1      16 [.    1466    1481 ..    1466    1489 .. 0.83
   3 ?   10.0   0.0   0.00011      0.96       1      27 [.    1609    1635 ..    1609    1643 .. 0.84
   4 ?   -3.9   2.0         2   1.8e+04       4      12 ..    1705    1713 ..    1702    1714 .. 0.86

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.011
                  HHHHHHHHCTTSTC CS
      PC_rep    2 AllALGlihaGsgn 15  
                   ++++Gl++++s  
  EEA19657.1 1419 GIMGIGLLYCNSQH 1432
                  79*********975 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.0061
                  HHHHHHHHHCTTSTCH CS
      PC_rep    1 GAllALGlihaGsgne 16  
                  +A +ALG i++G g +
  EEA19657.1 1466 AAGFALGYINLGKGKD 1481
                  699*********9988 PP

  == domain 3  score: 10.0 bits;  conditional E-value: 0.00011
                  HHHHHHHHHCTTSTCHHHHHHHHHHHH CS
      PC_rep    1 GAllALGlihaGsgneeaislLkpyls 27  
                  G ++A+Gl +aGs  + a++lL   l+
  EEA19657.1 1609 GLCFAIGLRYAGSAHSQARDLLIRFLD 1635
                  569******************976665 PP

  == domain 4  score: -3.9 bits;  conditional E-value: 2
                  HHHHHHCTT CS
      PC_rep    4 lALGlihaG 12  
                  +A+Gl+++G
  EEA19657.1 1705 MAIGLLFLG 1713
                  8******99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2071 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       449  (0.0250432); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 1.04u 0.31s 00:00:01.35 Elapsed: 00:00:00.51
# Mc/sec: 12210.12
//
Query:       EEA19658.1  [L=378]
Description: tyrosyl-tRNA synthetase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.5e-54  183.8   0.0    5.6e-54  183.5   0.0    1.1  1  tRNA-synt_1b  tRNA synthetases class I (W and Y)
  ------ inclusion threshold ------
       0.12   12.8   0.0       0.26   11.7   0.0    1.5  1  IMPa_helical  Immunomodulating metalloprotease helical domain
       0.16   11.4   0.0       0.53    9.7   0.0    1.8  2  Epimerase     NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> tRNA-synt_1b  tRNA synthetases class I (W and Y)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  183.5   0.0   9.3e-58   5.6e-54       5     291 ..      34     322 ..      30     324 .. 0.92

  Alignments for each domain:
  == domain 1  score: 183.5 bits;  conditional E-value: 9.3e-58
                   --EEEEEEETSSS-BGGGHHHHHHHHHHHHTTSEEEEEEEHHHHHTTTTT-SSHHHHHHHHHHHHHHHHHHH.HHTCHTTTEEEEETHHHHTTHHHH CS
  tRNA-synt_1b   5 plrvysGidPTgklHlGylvplkklvelqkaghevffliaDlhAiigdpskaeerklrkreevlenaikaql.akgldpekaevvlqsewlehlela 100
                     r+y+G+++Tg++H Gy+vp  k+++l+ ag+ev++l+aD+hA+++ ++ a+++ +++r++++e++i+a+l a+g++ ek+e+vl+s+++ ++e+ 
    EEA19658.1  34 TPRIYWGTATTGRPHSGYFVPAIKIAQLLAAGCEVVILLADVHAFLDSMK-APLELVENRVKYYEKVIRAILeAVGVSTEKLEFVLGSSYQRSSEYV 129
                   679***********************************************.*********************8899********************* PP

                   HHHHHHHTTCBHHHHHHHHHCCHHCSSSC--BHHHHHHHHHHHHHHHHTCHSEEEEEGGGHHHHHHHHHHHHHHHHHSTTSS-EEEEET-BBSTTSS CS
  tRNA-synt_1b 101 ellrdlgklgslnrmlqfksvkkrleegegislgeftYplLqaaDilllkadlvpgGsDQkqnielgrdlarrfnkkevfkkpegltvplltgldGe 197
                   +++ +l+ l+s ++  ++ +  + ++++ + +l+ ++Yp+Lq +D+ +lk+d ++gG DQ++ ++++ + +++++++    k+ +l++p++ gl+G+
    EEA19658.1 130 MDVYRLAALTSEHDAKKAGA--EIVKQSANAPLSGLLYPILQVLDEEYLKVDAELGGLDQRKLFVAATEWLPKLGYR----KRAHLVTPMVAGLNGG 220
                   *******************9..6666655679********************************************9....**************** PP

                   SBTTCETTCGC-BTTCCHHHHHHHHHHCHCSTTC..SHHHHHHHHHTHHH.........CHHHHHHHHCCSEE..ESSHHHHHHHHHCCCCHHHHHH CS
  tRNA-synt_1b 198 kKmSKSagnsaIfLddekesvkkkiqkavtdsde..evekllklktelsn.........elierleavsgkkp..kreaeellaeevtklvhggdlk 281
                    KmS+S + s+I+L+d+++ v kki+k    ++   +++    + ++l +         +   r+e   +++p  ++++++++ ++ ++ ++++  k
    EEA19658.1 221 -KMSSSIEDSKIDLLDSPDAVAKKIRKSEAIPKVveQNGIIAMIEYVLLPaaalagkkeF---RVER-RDEEPliYTDIQQIKDDYTKDILTPQLIK 312
                   .*******************************9998899999999999997776654222...2222.2333357899******************* PP

                   HHHHHHHHHH CS
  tRNA-synt_1b 282 kalaealnel 291
                    a+a+al++l
    EEA19658.1 313 PAAADALIRL 322
                   *****99886 PP

>> IMPa_helical  Immunomodulating metalloprotease helical domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   4.3e-05      0.26      27      86 ..      73     132 ..      57     140 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 4.3e-05
                   TTSTTH.HHHHHHHHHHHHHHHHHHHTT--GGGSSS-HHHHHHHHHHHHHHHH--S-B-T CS
  IMPa_helical  27 deeaklkeefkkaaesirsalealdsskidlfaeegyrlekllvLlaDkyRqeiryPmdk 86 
                    +++++ ++ k++ e + ++++ +++    +++  g+++ekl  +l+ +y ++ +y md 
    EEA19658.1  73 ADVHAFLDSMKAPLELVENRVKYYEKVIRAILEAVGVSTEKLEFVLGSSYQRSSEYVMDV 132
                   45788889999***********************************************97 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0      0.75   4.5e+03     187     211 ..      22      47 ..      14      57 .. 0.81
   2 ?    9.7   0.0   8.9e-05      0.53      58     111 ..      60     117 ..      52     131 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 0.75
                 HHHHHHHHTTS.SSEEEETTST-EEE CS
   Epimerase 187 palirkilegk.qevtllgdgtalRd 211
                 p li++ile+   + +++g+ t  R+
  EEA19658.1  22 PELIESILEKGgTPRIYWGTATTGRP 47 
                 77889999866679999998887665 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 8.9e-05
                 HHHHHHT-SEEEE--S---HHHHHHSHHHHHHHHTHHHHHHHHHHHHH.TCT....EEE CS
   Epimerase  58 rlfkeeqpdavihlAavggvaassedpadfieknlqgtlnlleaarka.gvk....rll 111
                 +l++  ++++vi+lA v    +s++ p +++e+ +++  +++ a+ +a gv      ++
  EEA19658.1  60 QLLA-AGCEVVILLADVHAFLDSMKAPLELVENRVKYYEKVIRAILEAvGVSteklEFV 117
                 5666.489******99****************************998765554444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (378 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       484  (0.0269954); expected 358.6 (0.02)
Passed bias filter:                      402  (0.0224218); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.25s 00:00:00.74 Elapsed: 00:00:00.41
# Mc/sec: 2746.80
//
Query:       EEA19659.1  [L=603]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-41  142.9   3.9    2.1e-40  138.7   3.9    2.2  1  Fungal_trans_2  Fungal specific transcription factor domain
    2.9e-06   27.3   9.8    2.9e-06   27.3   9.8    1.7  2  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.079   12.7   0.1      0.079   12.7   0.1    2.1  2  TAF4            Transcription initiation factor TFIID compone
       0.28    9.4   8.8       0.41    8.8   8.8    1.1  1  Spc7_N          N-terminus of kinetochore NMS complex subunit
       0.87    9.4   6.5       0.22   11.4   3.2    1.7  2  CCDC24          Coiled-coil domain-containing protein 24 fami
        1.5    8.7   3.5       0.32   10.9   0.3    1.5  2  Suf             Suppressor of forked protein (Suf)


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.7   3.9   7.1e-44   2.1e-40       1     356 [.     176     567 ..     176     580 .. 0.85

  Alignments for each domain:
  == domain 1  score: 138.7 bits;  conditional E-value: 7.1e-44
  Fungal_trans_2   1 elldyyldnvapllspvpessnpfrkvllplalsnkallhallalsafhlqskgpkdslereakrykslalkelqealaelsstlsrnekykdiL 95 
                     +lldy+++ + p +s +++ +np+++++ pl ls     +++la+sa +l+ +g   + ++ea+ yk++al++l +   + ++++        ++
      EEA19659.1 176 HLLDYFIRAIGPNCSLSSS-QNPYMSLV-PL-LSYTTFRNTILAVSANQLSLLGDTRY-SKEARMYKQKALTGLTQIGGTSTEDFG-------VV 259
                     599*********8887777.6****976.44.4555689***********88887776.******************999999999.......** PP

  Fungal_trans_2  96 aaiLllcsieissgdvsdwrvhLeaatsliksrggskasssslsskarfllrifayldilssttlgrgpsfpseeyekllenkkeesdsgldplm 190
                     a++L+lc+++is++++ +w +hL++  ++ +++      s + +s  rf+  +f+ +di+s+t+      +++e   ++len   ++ +++d  +
      EEA19659.1 260 ASVLMLCFHDISDNCSPSWVTHLRGGLDMTQYLPAG---SAQMESLKRFFNMYFVAHDIMSRTAPL---DCDDEPVHEWLEN---DDLDEIDTTV 345
                     **********************************99...9**********************9988...5555555555555...599******* PP

  Fungal_trans_2 191 GcsnslilliseisrLarekrsarkdseleplsileeaseleqrllswkprssdlepdldeterasslskdltelfrlaaliylyrlv....... 278
                     Gcs++l+ l s++s+Lar++r+ ++      +++ +++++    l+s+++++ +l  ++ +++++ ++     e++rl+al+y+   +       
      EEA19659.1 346 GCSRRLMTLVSQTSSLARQRRKVKDM----NSDFIRRCEDVGMGLESLHQKLPAL--TSTTESFILQIA----EIKRLSALLYFTENLgdlvsps 430
                     **************************....****************999998877..666666666665....************9998888888 PP

  Fungal_trans_2 279 .......................................lglpps.......................spevqelvkkllellellpsspvaias 311
                                                            +                            +   q lv+ +++l+++lp+ +   as
      EEA19659.1 431 llssathssrasyhtcsmptrlvyspssspfsstsspasP----AsttssttstsssssssssssknsTAIKQRLVSTIIDLISTLPNPNT--AS 519
                     8888888877777777777777777777666666655550....05555566666777777788888899999**************7555..9* PP

  Fungal_trans_2 312 LlWplFiaG..ceavdeddRdfvrrrleele.qsrlgnvrrarqvlee 356
                     ++Wpl i+G  + ++de++R+fv++rl++++  ++lgnvr++r  +e+
      EEA19659.1 520 VMWPLYIIGhsTGLEDEAQRRFVLERLRAIQsTRNLGNVRQVRLAVEK 567
                     *********98888888**************************99987 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   9.8   9.5e-10   2.9e-06       1      31 [.      15      45 ..      15      49 .. 0.95
   2 ?   -4.3   0.6         6   1.8e+04       5      10 ..      72      77 ..      70      79 .. 0.43

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 9.5e-10
                SS-HHHHHCT---STSSSS-HHHHHCTHHHC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCt 31
                ++C +C+ k+v+C ++kP+C++C++l+l+C+
  EEA19659.1 15 TGCFQCKEKHVQCTEEKPSCKRCERLGLQCV 45
                58****************************8 PP

  == domain 2  score: -4.3 bits;  conditional E-value: 6
                HHHHCT CS
     Zn_clus  5 nCrkkK 10
                +C++ K
  EEA19659.1 72 RCKRIK 77
                333333 PP

>> TAF4  Transcription initiation factor TFIID component TAF4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.1   2.6e-05     0.079      80     125 ..     347     392 ..     335     402 .. 0.94
   2 ?    0.2   0.8      0.18   5.3e+02     210     244 ..     472     497 ..     438     519 .. 0.54

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.6e-05
        TAF4  80 veerLrgLltklivlskhRrrgekskkrtesltsdvrkqLrelaqk 125
                 ++ rL +L+++++ l+++Rr++   ++ +    +dv   L++l qk
  EEA19659.1 347 CSRRLMTLVSQTSSLARQRRKVKDMNSDFIRRCEDVGMGLESLHQK 392
                 899*********************999999999*******999997 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.18
        TAF4 210 gggksgaskssssggkglkgksgviserGknglrl 244
                 + ++s +s+ssss+           s++ kn++++
  EEA19659.1 472 STTSSTTSTSSSSS---------SSSSSSKNSTAI 497
                 22222222222222.........222222222222 PP

>> Spc7_N  N-terminus of kinetochore NMS complex subunit Spc7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   8.8   0.00014      0.41     651     724 ..     427     500 ..     413     526 .. 0.78

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00014
      Spc7_N 651 gsPslasvrsrstrqslsrresttptsksrqssPvkskstpskqktpraarpstpaktppsskvksrsaSpkkl 724
                  sPsl s  ++s+r s ++ +  t    s++ssP +s+s+p+  +++  + +st++ +++ss+++  s+  k++
  EEA19659.1 427 VSPSLLSSATHSSRASYHTCSMPTRLVYSPSSSPFSSTSSPASPASTTSSTTSTSSSSSSSSSSSKNSTAIKQR 500
                 69******************99999999***********99965555555555555555555555555555544 PP

>> CCDC24  Coiled-coil domain-containing protein 24 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.1       2.5   7.4e+03      64      97 ..     152     182 ..     143     211 .. 0.59
   2 ?   11.4   3.2   7.2e-05      0.22     102     156 ..     455     507 ..     386     511 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 2.5
      CCDC24  64 rlLlqsLqekaaaegrdeeqllaqrsrrvldYvl 97 
                 +lL q+L+ ++     ++ +  +q +++ ldY +
  EEA19659.1 152 QLLSQTLKMRS---LGNPLSYYKQSEAHLLDYFI 182
                 44445555555...44555566667777777777 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 7.2e-05
      CCDC24 102 ersareespssrPesasskstaasaasgsssasalssasaelealkdkLNvsdiD 156
                 ++s+++ s+ s+P+s++s++  +s+ s+sss+s++ss+s++ +a+k++L  + iD
  EEA19659.1 455 SPSSSPFSSTSSPASPASTT--SSTTSTSSSSSSSSSSSKNSTAIKQRLVSTIID 507
                 56677777888888888855..888888889999999999999999988777776 PP

>> Suf  Suppressor of forked protein (Suf)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.3   0.2       4.7   1.4e+04     229     237 ..     144     152 ..     139     166 .. 0.47
   2 ?   10.9   0.3   0.00011      0.32     192     274 ..     433     516 ..     350     522 .. 0.68

  Alignments for each domain:
  == domain 1  score: -4.3 bits;  conditional E-value: 4.7
         Suf 229 rleqqrkse 237
                 +++qq++++
  EEA19659.1 144 HEQQQQQQQ 152
                 222222221 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00011
         Suf 192 pqaqeskkrklesedss...vkkPdklqmvespkkgaagrrleqqrksessksaeaasksqkalqqqpaplprsivallsvLPsaq 274
                 ++a++s+++++++ + +   v  P+++ +++  +++ a+++++ +++  +s+s+ ++s s k+    ++ l ++i+ l+s+LP+++
  EEA19659.1 433 SSATHSSRASYHTCSMPtrlVYSPSSSPFSS--TSSPASPASTTSSTTSTSSSSSSSSSSSKNSTAIKQRLVSTIIDLISTLPNPN 516
                 4455555555444443333455555555552..244444444555555555556666666667777777799***********986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (603 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1330  (0.0741815); expected 358.6 (0.02)
Passed bias filter:                      625  (0.0348597); expected 358.6 (0.02)
Passed Vit filter:                        79  (0.00440627); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.76u 0.31s 00:00:01.07 Elapsed: 00:00:00.47
# Mc/sec: 3882.97
//
Query:       EEA19660.1  [L=373]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (373 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       515  (0.0287244); expected 358.6 (0.02)
Passed bias filter:                      233  (0.0129957); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2528.16
//
Query:       EEA19661.1  [L=540]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.8e-16   58.9   0.1      7e-16   58.1   0.1    1.3  1  Fungal_trans    Fungal specific transcription factor domain
  ------ inclusion threshold ------
      0.091   12.0   0.2       0.62    9.3   0.1    2.1  2  EAP30           EAP30/Vps36 family
       0.12   12.8   0.4        6.5    7.2   0.0    2.6  2  Telomere_reg-2  Telomere length regulation protein
       0.28   12.2   3.2        8.4    7.4   3.0    2.5  2  Pap_E4          E4 protein


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.1   0.1   1.6e-19     7e-16       2     265 ..     108     361 ..     101     363 .. 0.79

  Alignments for each domain:
  == domain 1  score: 58.1 bits;  conditional E-value: 1.6e-19
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLl 98 
                   +rf + f+  +p++h +++l+  ++  s++ ++ +p   +ai+ + al  +++ + sn++  s+   ++    + + l        + +l  +q L+
    EEA19661.1 108 QRFLESFNATLPLFHAQTLLRLVHGFYSHEPQQRDPVAWAAINVVLALAYRQRLAGSNNTNCSVD--YL--NKAESVL--STIILGNIHLLNIQVLV 198
                   7999999*********9999999444455555555555555544444444444444444444433..22..2234444..488888999******** PP

  Fungal_trans  99 llelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddlwes 195
                    + + e+ s+d  ++  ++ +++rla+++gLh + s+++      l++++a +r +++w+a++lDk +++    p++  d++i+l LP  +  + + 
    EEA19661.1 199 GIVMLEQESQDLQHALILIATTMRLAHKIGLHNRASSEN------LDPADARQRACVFWMAYILDKDLSMRSKMPSIQLDDDIDLDLPSHEGAEYQI 289
                   ***********999999**********************......********************************************99988888 PP

  Fungal_trans 196 ddaseetlvetk...lsneeksrkiasflla..LkkilskiagsllsiekqlqqrdlqseklswveeleraldnW 265
                   +d+se +  ++    +  +   +k+++f+ +  L+ i +++++ l+s ++q +  +++      +e +  al++W
    EEA19661.1 290 NDESELNETGICrgvVTTMDGTVKMNYFVTRiqLAVIEGGVYDYLYSTRSQKRSAEER---SHALESVACALTTW 361
                   888888888888***9999999999999977115556666999999999998887777...55555555555555 PP

>> EAP30  EAP30/Vps36 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.1   0.00014      0.62      17      55 ..      24      61 ..      14      87 .. 0.81
   2 ?   -0.3   0.0      0.12   5.2e+02      11      60 ..     476     525 ..     471     531 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00014
       EAP30 17 qdlgaellaealqdleallakfkesLvklaekhkakiks 55
                +d  ++ ++++lq+le+l ++++e  vk+ae+h++ + +
  EEA19661.1 24 SDDDTSNTQSRLQHLETLVEELTE-HVKVAEEHNEVLDQ 61
                33447899****************.9********97765 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.12
       EAP30  11 qtaaeyqdlgaellaealqdleallakfkesLvklaekhkakiksdpafr 60 
                  t+  + +l ++l +  l  l++ +++ ++++v+  +++ +++ +d++ r
  EEA19661.1 476 RTQHDTPSLDDQLVEAGLGTLDKIIEETQSEVVRSFRDMCKELVQDSQRR 525
                 45555556789999999999999999999999999888888888888755 PP

>> Telomere_reg-2  Telomere length regulation protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.2     0.042   1.9e+02      14      41 ..      25      54 ..      18      65 .. 0.76
   2 ?    7.2   0.0    0.0015       6.5      18      52 ..     487     521 ..     466     538 .. 0.88

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.042
  Telomere_reg-2 14 kddyekieaaLksaeeLirrkad..eveen 41
                    +dd ++ ++ L+++e+L+++ ++  +v+e 
      EEA19661.1 25 DDDTSNTQSRLQHLETLVEELTEhvKVAEE 54
                    577789999**********98885655553 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0015
  Telomere_reg-2  18 ekieaaLksaeeLirrkadeveenaveLataLltl 52 
                     + +ea+L ++ ++i++ ++ev+    ++++ L++ 
      EEA19661.1 487 QLVEAGLGTLDKIIEETQSEVVRSFRDMCKELVQD 521
                     6799****************************975 PP

>> Pap_E4  E4 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   3.0    0.0019       8.4      30      78 ..       9      58 ..       4      82 .. 0.67
   2 ?    2.0   0.0     0.093   4.2e+02      12      34 ..     126     147 ..     123     174 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0019
      Pap_E4 30 pr.pwaprkkkrrrlssdsd.sssstspsspttkkseeespwtvtttgssv 78
                p+   +prk +r++++sd+d s+++++ +  +t  +e +++  v  ++ +v
  EEA19661.1  9 PCrKSTPRK-RRSSTKSDDDtSNTQSRLQHLETLVEELTEHVKVAEEHNEV 58
                451345566.78888888883444444444444444888888888887776 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.093
      Pap_E4  12 LLdLltt.ypttPprrppkprpwa 34 
                 LL+L++  y+++P++r p    wa
  EEA19661.1 126 LLRLVHGfYSHEPQQRDPV--AWA 147
                 9******889******886..354 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (540 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1215  (0.0677673); expected 358.6 (0.02)
Passed bias filter:                      924  (0.0515366); expected 358.6 (0.02)
Passed Vit filter:                        85  (0.00474092); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.69u 0.32s 00:00:01.01 Elapsed: 00:00:00.46
# Mc/sec: 3496.95
//
Query:       EEA19662.1  [L=299]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      2e-32  112.3   2.8    2.7e-32  111.8   2.8    1.1  1  adh_short        short chain dehydrogenase
    1.6e-22   80.2   2.6    6.8e-22   78.2   2.6    1.8  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    2.7e-13   50.2   0.5    3.7e-13   49.8   0.5    1.1  1  KR               KR domain
  ------ inclusion threshold ------
      0.013   15.0   0.5      0.098   12.1   0.5    2.1  1  Epimerase        NAD dependent epimerase/dehydratase family
      0.051   12.7   0.1      0.063   12.4   0.1    1.1  1  Polysacc_synt_2  Polysaccharide biosynthesis protein
      0.066   13.2   0.3       0.13   12.3   0.3    1.4  1  DUF1414          Protein of unknown function (DUF1414)
       0.12   12.5   0.6       0.19   11.8   0.6    1.3  1  Ldh_1_N          lactate/malate dehydrogenase, NAD binding do
       0.13   12.3   0.1       0.24   11.4   0.1    1.4  1  Shikimate_DH     Shikimate / quinate 5-dehydrogenase


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.8   2.8   1.2e-35   2.7e-32       2     191 ..      42     236 ..      41     239 .. 0.93

  Alignments for each domain:
  == domain 1  score: 111.8 bits;  conditional E-value: 1.2e-35
                 EEEEESTTSHHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHT....TSEEEEEE-TTTSHHHHHHHHHHHHHHH..SSESEEEE---S.S--SS CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvv.vdrseekleevakelkee....gakalaiqvDvtdreevealvekavkkl..gkldvLvnNAGi.tgsgp 92 
                 vv++tG++sGIG+a+a ++a++Ga  ++ ++r+ ++l+ +a+e+ ++     +k+++ +v++++r++v+++++ avk+    k+d++++NAGi +  g 
  EEA19662.1  42 VVFITGGGSGIGKATAIAFANAGAGAIAiFGRRLDRLQSAAEEVSKAnpngTTKVIFERVNLSQRAAVDTAFASAVKQAggAKIDIFIHNAGIlQTAGL 140
                 89**********************99998***************9988887788*************************7779**********888899 PP

                 GGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB.-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHH CS
   adh_short  93 fselseeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvp.vagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakel 190
                 ++ ++e+e+++ +e+N++g+f++++a++p +   s++++ n+sS +++ + ++g  aY+AsK a +++++ l+ e  +    +++v+PG+vdT++++++
  EEA19662.1 141 VAGYDENEYRKGLELNMVGAFNTVQAMFPLLA--SKAKVFNISSCIAHISvMPGCWAYAASKIANTKMFDYLQIENPD--LHIVNVHPGVVDTEINANT 235
                 99999999**********************77..99*********99665278999****************999877..699************9987 PP

                 C CS
   adh_short 191 r 191
                 +
  EEA19662.1 236 E 236
                 5 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.2   2.6     3e-25   6.8e-22       4     184 ..      50     237 ..      47     272 .. 0.86

  Alignments for each domain:
  == domain 1  score: 78.2 bits;  conditional E-value: 3e-25
                   TSHHHHHHHHHHHTT-E.EEEEESSGGH.HHHHHHHHHHTT...SEE..EE--TTSHHHHHHHHHHHHHHH..SSEEEEEE-----EGCSS-GGGH- CS
  adh_short_C2   4 sgIGraiAkalaeeGae.vvltdlneea.kkrveelaeelg...aev..lecDVtdeeqvealveevvekf..gklDilvnnagiapklkgpflets 91 
                   sgIG+a+A a+a++Ga  +++  ++ ++ ++++ee+ ++ +   ++v   +++ +++++v+++++ +v++    k+Di+++nagi ++  g ++  +
    EEA19662.1  50 SGIGKATAIAFANAGAGaIAIFGRRLDRlQSAAEEVSKANPngtTKVifERVNLSQRAAVDTAFASAVKQAggAKIDIFIHNAGILQT-AGLVAGYD 145
                   8**************964777766666668888888887664434455799********************6669************9.999999** PP

                   HHHHHHHHHHHTHHHHHHHHHHHHHCTSCCEEEEEEEGGGTSB.STTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTT CS
  adh_short_C2  92 reefdraldvnlyslfllakaalplmkeggsivnlssvgaerv.vpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikg 184
                   ++e+++ l+ n+ ++f++++a+ pl+++++++ n+ss  a+++ +p+  ay+a+K a  ++  yl  e  +    +  v+pg+++T+++++ ++
    EEA19662.1 146 ENEYRKGLELNMVGAFNTVQAMFPLLASKAKVFNISSCIAHISvMPGCWAYAASKIANTKMFDYLQIENPD--LHIVNVHPGVVDTEINANTEH 237
                   ***********************************9997776559********************888766..777779********9887764 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.8   0.5   1.6e-16   3.7e-13       2     152 ..      42     199 ..      41     215 .. 0.90

  Alignments for each domain:
  == domain 1  score: 49.8 bits;  conditional E-value: 1.6e-16
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-.EEEE----TT-HHHHHHHHHHHHHHS..S---EEEE------.--- CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealga.evevvaaDvsdkdavealleeikaee..ppikGvihaAgvlr.dkl 96 
                 +++itGG  g+G+++a   a+ ga  +++++R+    +++++++++ + +g+ +v + ++ +s+++av ++++++ +++  ++i   ih Ag+l+  +l
  EEA19662.1  42 VVFITGGGSGIGKATAIAFANAGAGAIAIFGRRLDRLQSAAEEVSKANPNGTtKVIFERVNLSQRAAVDTAFASAVKQAggAKIDIFIHNAGILQtAGL 140
                 679******************************988888899999999997659*****************99888877799*************4467 PP

                 TTT--HHHHHHHHTTTTHHHHHHHHHTTT...S--SEEEEEEEHHHHH--TT-HHHHHH CS
          KR  97 leemtaedleqvlapKvkGawnLhelled...esldffvlfSSiagllgsagqanYaaa 152
                 ++  +++++++ l+  + Ga n  +++ +   ++ ++f + S ia +  ++g  +Yaa 
  EEA19662.1 141 VAGYDENEYRKGLELNMVGAFNTVQAMFPllaSKAKVFNISSCIAHISVMPGCWAYAAS 199
                 8999****************99888876667799**********************996 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.5   4.4e-05     0.098       1     169 [.      43     224 ..      43     237 .. 0.68

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 4.4e-05
                 EEEETTTSHHHHHHHHHHHHCTSE.EEEEES-STTTTCHHCHHC..........EEEE--TT-HHHHHHHHHH.......HT-SEEEE--S.---HHHH CS
   Epimerase   1 ilVtGatGfiGsalvkallekgye.vigldrlssasntarledl..........elveldltdrsalerlfke.......eqpdavihlAa.vggvaas 80 
                 +++tG+   iG+a++ a++++g   +  + r+ ++ ++a++e             + +++l +r+a++ +f++        ++d+ ih A+  ++ +  
  EEA19662.1  43 VFITGGGSGIGKATAIAFANAGAGaIAIFGRRLDRLQSAAEEVSkanpngttkvIFERVNLSQRAAVDTAFASavkqaggAKIDIFIHNAGiLQTAGLV 141
                 689*******************664666666655555555554477889*****888888888887777776533333324799999988766555544 PP

                 HHSHHHH....HHHHTHHHHHHHHHHHHH.TCT.EEEEEEEGGGGTSCSSSSBSTCSTTS----SSHHHHHHHHHHHHHHHHHHHH.T-EEEEEEE CS
   Epimerase  81 sedpadf....ieknlqgtlnlleaarka.gvk.rllflsSsevYGkdaeqpkeettltgplkpnspYaaaKlageklveayaaqy.glnaiilrl 169
                 + + +      +e n++g+ n ++a++     k ++ ++sS ++          +++     +  ++Yaa+K+a  k+  +++ ++ +l+++++ +
  EEA19662.1 142 AGYDENEyrkgLELNMVGAFNTVQAMFPLlASKaKVFNISS-CIAH-------ISVM-----PGCWAYAASKIANTKMFDYLQIENpDLHIVNVHP 224
                 44444330011456777777777777755322225556655.4433.......3344.....7799999999999999999999998899988876 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   2.8e-05     0.063       1     115 [.      43     167 ..      43     215 .. 0.70

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2.8e-05
                      EEEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH......-TTEEEE....E--TT-HHHHHHHT....T.....T-SEEEE---- CS
  Polysacc_synt_2   1 vlvtGagGsiGselvrqilkkkpkkiillerdElklyeiekeleeelkkkklkveivpvigdvrdkerlekal....ee...lkvdvvfhaAAl 87 
                      v++tG+g  iG++    +++  +  i ++ r   +l++ ++e+++   + ++kv       ++ +++ +++a+    ++    k+d+ +h A +
       EEA19662.1  43 VFITGGGSGIGKATAIAFANAGAGAIAIFGRRLDRLQSAAEEVSKANPNGTTKVI--FERVNLSQRAAVDTAFasavKQaggAKIDIFIHNAGI 134
                      79*********************************99999997766665544333..2233334444444333000033222588999999887 PP

                      --HH.HH....HHSHHHHHHHHHHHHHHHHHHH CS
  Polysacc_synt_2  88 KhVP.lv....eenpleaiktNvlgtenvieaa 115
                       +   lv    e++  ++++ N++g+ n+++a 
       EEA19662.1 135 LQTAgLVagydENEYRKGLELNMVGAFNTVQAM 167
                      664312223335666788888999988888875 PP

>> DUF1414  Protein of unknown function (DUF1414)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.3   5.8e-05      0.13      14      42 ..      91     119 ..      91     120 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 5.8e-05
                 HHHHHHHTTTS-CCCHHHHHHHHHHHHHH CS
     DUF1414  14 NmvTnilnssVpeaqRealAekFaqALkn 42 
                 N +T ++ ++V+ +qR+a+  +Fa+A k+
  EEA19662.1  91 NGTTKVIFERVNLSQRAAVDTAFASAVKQ 119
                 678***********************987 PP

>> Ldh_1_N  lactate/malate dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.6   8.4e-05      0.19       3     101 ..      43     138 ..      41     146 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 8.4e-05
                 EEEETTTSHHHHHHHHHHHHTTSSSEEEEE-SSHHHHHHHHHHHHHCHCCSTS-EEEEESSGGGGTTESEEEE--S-SS-TTTTHHHHHHHHHHHHHHH CS
     Ldh_1_N   3 vavvGaaGgiGqslalllankkladelaLlDiakekleGvaldlshistflsvkvkvsekeeealkdadvvvitagvprkpGetRddLlkvNakIvkei 101
                 v ++G + giG+++a++ an + +  +a++  + ++l+  a ++s ++ + ++kv+ ++ + +  + +d +   a++ ++ G    d +  Na+I+++ 
  EEA19662.1  43 VFITGGGSGIGKATAIAFANAGAGA-IAIFGRRLDRLQSAAEEVSKANPNGTTKVIFERVNLSQRAAVDTA--FASAVKQAGGAKIDIFIHNAGILQTA 138
                 789999889***************9.*************************99999988777777777776..6888999999************9875 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1   0.00011      0.24      10      59 ..      38      88 ..      32     109 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00011
                  .TT-EEEEES-SH.HHHHHHHHHHCCT-CEEEEEESSHHHHHHHHHHHT.E CS
  Shikimate_DH 10 lkekkvlliGaGe.maelvakhLlakgvkkvvvaNRtlerakelaeelkge 59
                  ++e+ v + G G  +++ +a +++++g+ ++++++R l+r ++ aee++++
    EEA19662.1 38 VSESVVFITGGGSgIGKATAIAFANAGAGAIAIFGRRLDRLQSAAEEVSKA 88
                  567778888999747889999**************************9766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (299 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       484  (0.0269954); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.49
# Mc/sec: 1837.15
//
Query:       EEA19663.1  [L=503]
Description: allantoate permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      7e-26   91.0  29.6      7e-26   91.0  29.6    1.9  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.034   14.3   0.1      0.089   13.0   0.1    1.7  1  ESSS      ESSS subunit of NADH:ubiquinone oxidoreductase (com


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.0  29.6   7.9e-30     7e-26       2     353 .]      39     404 ..      37     404 .. 0.77
   2 ?    0.7   5.8     0.022   1.9e+02      13      90 ..     363     441 ..     354     445 .. 0.66

  Alignments for each domain:
  == domain 1  score: 91.0 bits;  conditional E-value: 7.9e-30
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrr.vlllglllfalglllllfasslw.lllvlrvlqGlg 98 
                 ll+a l a +  ++++a+   l +dl++++ +++++ ++ ++g+++++ p +++ +r+ + + +  +++ +++l+ll+++  s  +  l++lr+l+G  
  EEA19663.1  39 LLTATLGAVDKVAISTAAIYGLRDDLHLTGNQYSWAGSILYFGCVFGMWPSSYVLQRVPSAKyLASCSFGWSILSLLIPA--SRNFsHLMILRFLMGCL 135
                 45555556666666666666**************************************9888688888888888877777..666669*********** PP

       MFS_1  99 agalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg......Wravfyilaivsllafvlfllllpeepperkrkspkeee... 188
                 +g+++p++  +ia  ++k e++  ++++ a  ++++++   l+ ++ +  +      W+++f+i + +sl +  +++l+lp++p + +  +++e+    
  EEA19663.1 136 EGIIVPSISLVIAGFYKKAEQPPRNAVAFA--AISSVINGFLSWAVGQIPSsaplakWQYLFLITGTISLAWSFVAFLYLPDTPMNAWFLNEREKYyii 232
                 *********************999987766..4445555444444444444667999***************99999******************9*** PP

       MFS_1 189 ............kgtgpaplvpawkallkdpvlwillialllfffgfsg....lltllplylqevlglsglllaglllallalvgailallagrlsdrl 271
                             k +++ ++    +a+  ++     +i++l++  +++     l t+  + ++  lg+s +++++ll + +++++  +a+ +++l+ ++
  EEA19663.1 233 trlaenktgivsKTWKREQA---VEAIIDPK----TWIIFLFNI-AINVpnggLITFNGI-IVNNLGFS-AVQTSLLNMPTGIMSTLSAFGFSWLAAKW 321
                 99887775554444444444...55888888....677766664.555545554444444.4*******.8*************************999 PP

       MFS_1 272 grrrrlllallllllaalglallavt.ssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfntagslggalgp 353
                  +rr l+ ++++++ a  ++++ a++ ++    +++++l+ + +g ++  +    ++ a+  +   +++++ + +++g ++gp
  EEA19663.1 322 TNRRCLVTMIAAFVPAIGAILVYALPrKNIGGQMVGIYLLYTYFGPYVLGISLGQANTAGHTKKSVQYSIMYIGYAVGNLIGP 404
                 99888888888888888888888888755566666555555544443333333333333456788899999999999999998 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.022
       MFS_1  13 silgpalpl.alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllll.fasslwlllv 90 
                 + +gp +    l+++ ++ ++  +  +++ ++g+av++l++ + + r    + +  g+++++++ ++++  +  ++w+l++
  EEA19663.1 363 TYFGPYVLGiSLGQANTAGHTKKSVQYSIMYIGYAVGNLIG-PQTFRANQAPAYTGGFVSMLICyCVCIGlM-GTYWILAA 441
                 33444433335555555666667789999999999999865.454577788899999999999966666655.78885554 PP

>> ESSS  ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.1   9.9e-06     0.089      49      87 ..     189     227 ..     181     241 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 9.9e-06
        ESSS  49 enmeavfffgvsivlVlgsvfvaYlpdtsiqeWArrEAe 87 
                  +++  f ++ +i+l +  v++ Ylpdt ++ W   E e
  EEA19663.1 189 AKWQYLFLITGTISLAWSFVAFLYLPDTPMNAWFLNERE 227
                 579999999************************887755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (503 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       692  (0.0385967); expected 358.6 (0.02)
Passed bias filter:                      343  (0.019131); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.25s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 3393.67
//
Query:       EEA19664.1  [L=552]
Description: glycyl-tRNA synthetase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.2e-22   78.5   0.7      9e-22   77.0   0.0    2.2  3  HGTP_anticodon  Anticodon binding domain
    2.6e-07   30.8   0.0    6.7e-07   29.5   0.0    1.7  1  tRNA-synt_2b    tRNA synthetase class II core domain (G, H, P


Domain annotation for each model (and alignments):
>> HGTP_anticodon  Anticodon binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.1       1.5   1.3e+04      58      74 ..      35      50 ..      28      66 .. 0.52
   2 ?   -2.4   0.0      0.63   5.7e+03      41      53 ..     190     202 ..     176     234 .. 0.57
   3 !   77.0   0.0     1e-25     9e-22       1      93 [.     436     527 ..     436     528 .. 0.96

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 1.5
                    EE-HHHHHHTEEEEEET CS
  HGTP_anticodon 58 vvGekelekgtvtvrdr 74
                    ++++ke ++ +v  ++ 
      EEA19664.1 35 TIDAKE-DDAKVDAKKQ 50
                    444444.2333333333 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.63
                     HHHHHHHHHHTT- CS
  HGTP_anticodon  41 igkkireadllgi 53 
                      gkk ++ d+++ 
      EEA19664.1 190 GGKKHHRFDEIKD 202
                     5666666666553 PP

  == domain 3  score: 77.0 bits;  conditional E-value: 1e-25
                     SEEEEESSSSHHHHHHHHHHHHHHHHTTTSEEEEESSSSTHHHHHHHHHHTT-SEEEEE-HHHHHHTEEEEEETTTCEEEEEETTHHHHHHHH CS
  HGTP_anticodon   1 qvvviplnekaeeleeyakklaeeLraagirvelddsnesigkkireadllgipfavvvGekelekgtvtvrdrdtreqervsldelveklke 93 
                     +v+++pl++    + +  +k+ + Lr+ gi++ +dds+ sigk++++ d+lgip+ +++++++++++++t+r+rd+++q+r s+de+++ +k+
      EEA19664.1 436 KVLIVPLSN-LPTFVPIIRKISQNLRRLGISCRVDDSGASIGKRYARNDELGIPLGITIDFDTVKDDSITLRERDSTRQVRASIDEIIASIKS 527
                     799*****9.7779**************************************************************************99986 PP

>> tRNA-synt_2b  tRNA synthetase class II core domain (G, H, P, S and T)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.5   0.0   7.4e-11   6.7e-07      12      79 ..     126     195 ..     123     223 .. 0.84

  Alignments for each domain:
  == domain 1  score: 29.5 bits;  conditional E-value: 7.4e-11
                   EE-SSSHHHHHHHHHHHEE..EBGGSSEEEEEEEEEEBTTTSTBCTTTB-SEEEEEEEEEEES.GGGHHHH CS
                   xxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxx RF
  tRNA-synt_2b  12 iLkPtneetfvelirdevl..rskrLPlklyqiqtkyRdEksdsrGLlRvreFhqkdgyvfha.easldds 79 
                   +L+P+  ++    +++  l  +++ +P+  + ++  +R+E s  +GLlRvreF + + + f+  e+  +  
    EEA19664.1 126 YLRPETAQGQFLNFKKL-LeyNQNTMPFASASVGKSFRNEISPRSGLLRVREFLMAEIEHFVDpEGGKKHH 195
                   79999999999999876.6578889****************9555****************9955544444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (552 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       667  (0.0372023); expected 358.6 (0.02)
Passed bias filter:                      512  (0.0285571); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.44
# Mc/sec: 3797.49
//
Query:       EEA19665.1  [L=466]
Description: transcription factor Rba50, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.5e-25   87.6   0.0    7.5e-25   86.8   0.0    1.4  1  RPAP1_C   RPAP1-like, C-terminal
      3e-18   65.3   9.9    5.4e-18   64.5   9.9    1.4  1  RPAP1_N   RPAP1-like, N-terminal
  ------ inclusion threshold ------
       0.21   11.2   1.3       0.36   10.4   1.3    1.3  1  DUF4085   Protein of unknown function (DUF4085)


Domain annotation for each model (and alignments):
>> RPAP1_C  RPAP1-like, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.8   0.0   1.3e-28   7.5e-25       2      66 ..     310     376 ..     309     377 .. 0.96

  Alignments for each domain:
  == domain 1  score: 86.8 bits;  conditional E-value: 1.3e-28
     RPAP1_C   2 lRFdfdGdlvpl..adelethrgLhhHgdepalaGYTlkElfqLarSavpsQralalqtLgrilekl 66 
                 +RF+f+G+++p+  + el+t+ gLhhH+d+p++aGYT++El  L+rS+vp+Qr++a q+Lgril +l
  EEA19665.1 310 IRFSFRGEMLPPstSLELPTSLGLHHHADDPEAAGYTISELSILSRSTVPAQRCVAWQVLGRILFRL 376
                 7***********888999**********************************************886 PP

>> RPAP1_N  RPAP1-like, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.5   9.9     9e-22   5.4e-18       3      46 .]     117     160 ..     115     160 .. 0.97

  Alignments for each domain:
  == domain 1  score: 64.5 bits;  conditional E-value: 9e-22
     RPAP1_N   3 IdeENrarLasMspeEIeeereeLlesLdPkllefLlkRankke 46 
                 IdeEN++r+a+Ms+eEIe+e++eL+++L P+l+e+Ll+Ran++e
  EEA19665.1 117 IDEENKQRIAAMSEEEIEQEKAELMANLPPSLIERLLRRANIDE 160
                 9****************************************996 PP

>> DUF4085  Protein of unknown function (DUF4085)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   1.3     6e-05      0.36      22      64 ..     110     151 ..     103     188 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 6e-05
     DUF4085  22 kdweeelaeekeegedleellkeeleelKedLLkfLPkeilpy 64 
                 +d e+    ++e+ + + ++ +ee+e+ K++L+  LP ++++ 
  EEA19665.1 110 EDEEK-RIIDEENKQRIAAMSEEEIEQEKAELMANLPPSLIER 151
                 44444.4445667789*********************988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (466 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1095  (0.0610742); expected 358.6 (0.02)
Passed bias filter:                      486  (0.0271069); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.59u 0.25s 00:00:00.84 Elapsed: 00:00:00.43
# Mc/sec: 3255.12
//
Query:       EEA19666.1  [L=981]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.3e-08   33.4   0.2    9.1e-08   32.0   0.2    1.8  1  HUN        HPC2 and ubinuclein domain


Domain annotation for each model (and alignments):
>> HUN  HPC2 and ubinuclein domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.0   0.2   5.1e-12   9.1e-08       5      51 ..     778     821 ..     775     822 .. 0.82

  Alignments for each domain:
  == domain 1  score: 32.0 bits;  conditional E-value: 5.1e-12
         HUN   5 rdddgddtgsgYDieDpFIDDsElydelvpdilktktgGFYvnqgel 51 
                 +++ + +++++YD +DpF+DDsEl+   +   +   ++GF+v++g l
  EEA19666.1 778 KKKRRKKKIEEYDRDDPFVDDSELVWQEQ---AAASKDGFFVYSGPL 821
                 444455679**************999888...677789******976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (981 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2634  (0.146913); expected 358.6 (0.02)
Passed bias filter:                      646  (0.036031); expected 358.6 (0.02)
Passed Vit filter:                       365  (0.0203581); expected 17.9 (0.001)
Passed Fwd filter:                       143  (0.0079759); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 2.86u 0.46s 00:00:03.32 Elapsed: 00:00:00.75
# Mc/sec: 3962.60
//
Query:       EEA19667.1  [L=482]
Description: IFRD domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.8e-86  288.4   5.4    7.8e-86  287.9   5.4    1.2  1  IFRD      Interferon-related developmental regulator (IFRD)
      6e-05   22.4   0.5    0.00017   20.9   0.2    1.8  2  Cnd3      Nuclear condensing complex subunits, C-term domain
  ------ inclusion threshold ------
        0.1   11.6   3.3      0.063   12.3   1.3    1.6  2  DUF4698   Domain of unknown function (DUF4698)


Domain annotation for each model (and alignments):
>> IFRD  Interferon-related developmental regulator (IFRD)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  287.9   5.4   1.3e-89   7.8e-86       1     306 []      54     376 ..      54     376 .. 0.93

  Alignments for each domain:
  == domain 1  score: 287.9 bits;  conditional E-value: 1.3e-89
        IFRD   1 sDdes......ssdtlSvlsssSetasveegeedeeeaqedweekLkqaidelt...eksaktReaaLesllellsshyleefveerlatlldaleksl 90 
                 sDde+      +++t+S  ++s     +++ +++ e+++ dw e+L ++++++    ++s+++Re++L+++++l + hy+ee+++ ++++ll+a+++s+
  EEA19667.1  54 SDDEDegnlsdETETWS--TGS-----LDDLADNPESDNVDWPEELADCMQDILdrkRSSVQGREESLSAFCRLAKFHYVEEEIRGSIQDLLAAFLRSI 145
                 57777345444455555..444.....344444599*************************************************************** PP

        IFRD  91 kkgkse.EqalAlkalallcitlgagdeseeileelkpvLkriikdssvslsakaaaieaLglltfvggadeeeieelmeflleifssdgqsieaadsa 188
                 k + s  E +lAlkal+ l++t    + +++i+++++++L+++i+ds+ s  +k+aai++Lg+++++gg +e++ +++m++ll+i++sdgqsiea+ + 
  EEA19667.1 146 KYEGSVrESVLALKALEFLAVT----AYDDTIYDAVESLLTKTIRDST-SGLIKVAAINCLGTCAYFGGTSEDAKMDQMNMLLDIITSDGQSIEASADY 239
                 ***9999***************....99********************.************************************************** PP

        IFRD 189 skalvtaalsawglLltllpssklnkkleedleealealvelLdssdvevriAAGeaiALlfElsreedeefeeeeee..................... 266
                 +  +vtaal++wg+L+t +      ++le d ee++e l+e+L s d +v+iAAGe+iALl+E+s++++ee++e +e+                     
  EEA19667.1 240 G--VVTAALQQWGFLATDV------EDLEADSEEVVEILIEQLASVDSNVQIAAGENIALLYEKSYTPQEEEDEIDEDeldeegeggdssasggpklie 330
                 *..****************......4444444779*********************************99998777779******************** PP

        IFRD 267 ......dteelleqlreLatdssKkraKkDrkkqRsvFrdvlttiE 306
                       d+ +l++ l +Lat s+K+++KkD+k+++++F+++ltt+E
  EEA19667.1 331 rypayhDKYHLEQILASLATVSGKRISKKDKKSLHTNFASILTTVE 376
                 *********************************************9 PP

>> Cnd3  Nuclear condensing complex subunits, C-term domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.2   2.8e-08   0.00017      16     145 ..     166     290 ..     153     331 .. 0.88
   2 ?   -1.1   0.0      0.14   8.5e+02      92     135 ..     291     379 ..     288     388 .. 0.60

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 2.8e-08
                 -TTSCCHHHHHHHHTHHHHHC-S.SHHHHHHHHHHHHHHHTT-H...HHHHHHHHHHHHHHHHS-HHHHHHH.HHHHHHHHHHH-CGGGGGGHH..... CS
        Cnd3  16 sleenpsleslleslilpavrsk.eaairelglkcLglfclldk...klakenlklflqalskgneelkiia.lkaifDllllhglevldkekkedsde 109
                 ++  + ++ + +esl++  +r +    i  +++ cLg+++ +     +   + + ++l++++++ ++++++a   +++  l   g+   d e+ e +  
  EEA19667.1 166 VTAYDDTIYDAVESLLTKTIRDStSGLIKVAAINCLGTCAYFGGtseDAKMDQMNMLLDIITSDGQSIEASAdYGVVTAALQQWGFLATDVEDLEAD-- 262
                 5566778899999*******999899**************9977555888999*********99********999***********99999876533.. PP

                 .........HHHHHHHHHHC-TT-HHHHHHHHHHHH CS
        Cnd3 110 eeeesessksllkllykaLdsednpelqaiaaeglc 145
                        s++++++l+++L s d +++q +a+e ++
  EEA19667.1 263 -------SEEVVEILIEQLASVD-SNVQIAAGENIA 290
                 .......459*********9995.********9887 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.14
                 HHH-CGGGGGGHH...........................................................HHHHHHHHHHC-TT-HH CS
        Cnd3  92 llhglevldkekkedsd.eeeees............................................essksllkllykaLdsednpe 135
                 ll+  ++  +e++++ d +e +e+                                            +++ksl++ ++++L++ +np 
  EEA19667.1 291 LLYEKSYTPQEEEDEIDeDELDEEgeggdssasggpklierypayhdkyhleqilaslatvsgkriskKDKKSLHTNFASILTTVENPR 379
                 55566555555554444322222255666666666666666666666666666666666666666766777777777887777776665 PP

>> DUF4698  Domain of unknown function (DUF4698)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   1.3   1.1e-05     0.063     173     262 ..      14     108 ..       4     140 .. 0.72
   2 ?   -2.8   0.0       0.4   2.4e+03      68     101 ..     350     383 ..     335     388 .. 0.71

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.1e-05
     DUF4698 173 kipvlrktskklsrkgsklslsrvsggsspqssvv.Slnpgsdeva.lssaltqvtsskeiedne...ssstkedeellsikLQklleivredvr 262
                 k+  ++++s+ +sr +s+++ +++s ++s qss + S  p++de +   s  t+  s+++++d      s++ +  e l + +Q +l+  r +v+
  EEA19667.1  14 KTVSRKAASREASRSTSRVASAQTSRQNSRQSSRAaSRYPSDDEDEgNLSDETETWSTGSLDDLAdnpESDNVDWPEELADCMQDILDRKRSSVQ 108
                 3444457899999999999999***********99899998777651234444555555555544333555555556677777777777776665 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.4
     DUF4698  68 essakkskkkkkkallrpftPvhssllspslsea 101
                 + s k+  kk+kk+l  +f+ + +++  p+l  a
  EEA19667.1 350 TVSGKRISKKDKKSLHTNFASILTTVENPRLGPA 383
                 4466788888888899999999988888887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (482 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1110  (0.0619109); expected 358.6 (0.02)
Passed bias filter:                      645  (0.0359752); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.43
# Mc/sec: 3341.67
//
Query:       EEA19668.1  [L=86]
Description: hypothetical protein PMAA_004470 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.7e-07   30.4   1.6    1.8e-07   30.3   1.6    1.0  1  Transp_cyt_pur  Permease for cytosine/purines, uracil, thiami
  ------ inclusion threshold ------
      0.033   14.0   0.3      0.035   14.0   0.3    1.1  1  CHD5            CHD5-like protein
       0.12   12.1   0.1       0.17   11.6   0.1    1.2  1  Ail_Lom         Enterobacterial Ail/Lom protein
       0.33   11.1   3.5        1.5    9.0   1.5    2.1  2  DUF1029         Protein of unknown function (DUF1029)


Domain annotation for each model (and alignments):
>> Transp_cyt_pur  Permease for cytosine/purines, uracil, thiamine, allantoin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.3   1.6     4e-11   1.8e-07     133     198 ..      12      80 ..       4      86 .] 0.84

  Alignments for each domain:
  == domain 1  score: 30.3 bits;  conditional E-value: 4e-11
  Transp_cyt_pur 133 tsltelvtffifwvvslvivllgvskirkffviaallvpvaafgfliwalvkaeg...Gpvldkavklg 198
                     +++ ++v+f+ + vv+l+ +l   skir++f ++a+++p+aa g+  wa+++ +g   G++    +k++
      EEA19668.1  12 ITTQVMVGFLLAFVVTLPLMLIHTSKIRHLFSLKAVVFPIAALGVVCWAMSANGGvsaGALQATTSKPS 80 
                     78999***********************************************99985555544444444 PP

>> CHD5  CHD5-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.3   7.8e-06     0.035      98     153 ..      17      71 ..       4      77 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 7.8e-06
        CHD5  98 klkkvllvlttvpqlvlkfwyrktpvfylpkgwfPllvewllslplaplgsVSlti 153
                  +  +l +++t+p +++   +   ++f l+  +fP ++ +++ +++   g+VS ++
  EEA19668.1  17 MVGFLLAFVVTLPLMLIHTSKI-RHLFSLKAVVFPIAALGVVCWAMSANGGVSAGA 71 
                 5667788899999888887765.569***************************986 PP

>> Ail_Lom  Enterobacterial Ail/Lom protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.1   3.7e-05      0.17       9      46 ..      44      82 ..      38      85 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 3.7e-05
     Ail_Lom  9 lsavvl.lvvagvpasaaehqstlsagylqastdapgsd 46
                l avv+ +++ gv ++a   +  +sag lqa+t  p s 
  EEA19668.1 44 LKAVVFpIAALGVVCWAMSANGGVSAGALQATTSKPSST 82
                55666536778*************************986 PP

>> DUF1029  Protein of unknown function (DUF1029)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   1.5   0.00034       1.5      10      41 ..      18      49 ..      14      51 .. 0.87
   2 ?    2.4   0.0     0.038   1.7e+02       7      25 ..      50      68 ..      50      71 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00034
     DUF1029 10 LlgilcaallaNfvlsrktKldiiFvlqsilF 41
                 ++ l +++ + ++l   +K+  +F+l++++F
  EEA19668.1 18 VGFLLAFVVTLPLMLIHTSKIRHLFSLKAVVF 49
                55677888889999999**************9 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.038
     DUF1029  7 PllLlgilcaallaNfvls 25
                P+  lg++c a+ aN  +s
  EEA19668.1 50 PIAALGVVCWAMSANGGVS 68
                666799********97665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (86 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       625  (0.0348597); expected 358.6 (0.02)
Passed bias filter:                      293  (0.0163422); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.44
# Mc/sec: 589.25
//
Query:       EEA19669.1  [L=77]
Description: hypothetical protein PMAA_004480 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.8e-12   46.8   0.2      2e-12   46.6   0.2    1.0  1  Transp_cyt_pur  Permease for cytosine/purines, uracil, thiami


Domain annotation for each model (and alignments):
>> Transp_cyt_pur  Permease for cytosine/purines, uracil, thiamine, allantoin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.6   0.2   1.1e-16     2e-12     366     429 ..       1      65 [.       1      72 [. 0.88

  Alignments for each domain:
  == domain 1  score: 46.6 bits;  conditional E-value: 1.1e-16
  Transp_cyt_pur 366 iiadyfvvrrgylklaalytrrrgsaYwyrkgvNwravaayivGiaaglvgvagsvg.ikvvkga 429
                     + +dyf +rrg+l++ +++t +r+++Y y++gvNw+ va +i+G  + l+g++ s+g +++ + a
      EEA19669.1   1 MTVDYFLIRRGNLHISEMFTTSRSGRYCYTYGVNWTGVAGFIAGFCLPLPGFIQSFGtVTTNPAA 65 
                     578***************************************************99944444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (77 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      283  (0.0157845); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.35u 0.22s 00:00:00.56 Elapsed: 00:00:00.37
# Mc/sec: 620.67
//
Query:       EEA19670.1  [L=1012]
Description: oxysterol binding protein (Osh3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   1.8e-115  385.8   0.0   3.9e-115  384.6   0.0    1.6  1  Oxysterol_BP  Oxysterol-binding protein
    2.3e-38  130.4   0.2    4.7e-38  129.4   0.2    1.6  1  PH_8          Pleckstrin homology domain
    1.9e-06   28.3   0.0    4.6e-06   27.1   0.0    1.7  1  PH            PH domain
  ------ inclusion threshold ------
      0.021   15.2   0.4       0.45   11.0   0.4    2.5  1  PH_11         Pleckstrin homology domain


Domain annotation for each model (and alignments):
>> Oxysterol_BP  Oxysterol-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  384.6   0.0  8.8e-119  3.9e-115       1     373 []     628     996 ..     628     996 .. 0.93

  Alignments for each domain:
  == domain 1  score: 384.6 bits;  conditional E-value: 8.8e-119
                   HHHCCHTTSTT-BCCCS---GGGEEEEEHHHHHHHCCTTCHHHHHHHC.SSHHHHHHHHHHHHHHCCCGCT..STSSSEEE---TT-EEEEEETTCE CS
  Oxysterol_BP   1 slwsilkkciGkDLskislPvffneplSlLqrlaedleyselLdkaakeddsleRlayVaaFalSsyasti..krrlkKPFNPlLGEtfelvredkg 95 
                   sl+ +l+k++GkDLs +s+Pv+ neplSlLqr ae +eys lLdkaa+  d leRl+yV+aFalSs+++++   r+++KPFNPlLGEtfelvred+g
    EEA19670.1 628 SLIGFLRKNVGKDLSAVSMPVTANEPLSLLQRAAECMEYSPLLDKAASAIDGLERLVYVTAFALSSLSTNRvkDRAVRKPFNPLLGETFELVREDRG 724
                   6999********************************************999*******************99999********************** PP

                   EEEEEEEEETTTTEEEEEEEECTEEEEEEEEEEEEE-SSEEEEEE-SEEEEEEEEESEEEEEEE--EEEEE-TTTTS-EEEEEEEEEEEETTT--EE CS
  Oxysterol_BP  96 frfiaEQVsHhPpvsAfhaesegweldgeikvkskflgkslevkpeGtahlellkksgehYtwtkpttivhniivgklwvelsgeveitnhstgdka 192
                   fr+i E+VsH+P   A+ a+s++w+l+++ k+++kf+gks+e++++G+++l+l ++sg+h++w ++t++++nii+g+++ve +ge+ ++n++tg+k+
    EEA19670.1 725 FRMIVEKVSHRPVQLAYQADSRDWSLTQSPKPTQKFWGKSAEINTDGKTRLSL-HSSGDHFSWGNATSFLRNIIAGEKYVEPVGEMVVVNETTGQKT 820
                   *****************************************************.88***************************************** PP

                   EEEEE---SSS---SSEEEEEEEE.TTS-EEEEEEEETTTEEEEEETTSTTS--EEEEETT-BSXXGCGSSTTBCCCCCCH---.--...GGG--HH CS
  Oxysterol_BP 193 kleFkkkglfsskksnkvegkvkd.kkkevlyeisGkwdeelyikkkktekkeeeedasekskvkekeeqeefeseklWkaspl.pkaeeyygftkf 287
                   + +Fk+ g+f s++s++v +k +d + +e    ++G+w+++l+++++                        +++++++W+  pl ++a++ ygf  f
    EEA19670.1 821 ISTFKAGGMF-SGRSEEVAVKAFDvHGNELPLGLAGTWTNSLQLTEH-----------------------GSTTNKTIWSVGPLvDQASKRYGFPIF 893
                   **********.599**********66678899************444.......................346789********999999******* PP

                   HHCCT---.TT.GGS-TTBGGG-HHHHHHHTT-HHHHHHHHHHHHHHHHHHHHHHCCTT.----SSEEEEE............TTTTSSCEEEC... CS
  Oxysterol_BP 288 avtlNeieeke.kslaptDsRlRpDqraleegdideAeeeKkrlEekQRerrkereekk.ewkpkwFekek............dpdtgeevwky... 367
                   + tlNe+++ e  +l+ptDsRlRpDqrale++d+d+Ae+ K +lEekQRerrke e+ +  +kp+wF++++             + ++e +wk    
    EEA19670.1 894 TATLNETTPIEqGKLPPTDSRLRPDQRALENNDVDTAEDLKAKLEEKQRERRKELEDIGaVYKPRWFSRVDtsdvsstaegsaGSGSEEVTWKLktg 990
                   *********8879******************************************888756********9988777776665523456667776445 PP

                   -S-HHH CS
  Oxysterol_BP 368 kgeywe 373
                   k++ywe
    EEA19670.1 991 KDGYWE 996
                   667775 PP

>> PH_8  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  129.4   0.2     1e-41   4.7e-38       1      88 [.     228     315 ..     228     316 .. 0.99

  Alignments for each domain:
  == domain 1  score: 129.4 bits;  conditional E-value: 1e-41
        PH_8   1 gillkkrrkklqgyakRfFvLdlksstlsYyrddnssalrgkiplslaiisaneekreiiidsGaevWeLkasnekdfqeWvealeka 88 
                 gil+k+rrk++qg+a+RfF+Ld++sstlsYy+d+nssalrg+iplsla+++an+++rei+idsGae+W+L+a n++df +W  ale+a
  EEA19670.1 228 GILQKRRRKRHQGWARRFFSLDYTSSTLSYYHDRNSSALRGAIPLSLAAVAANADRREISIDSGAEIWHLRAINQSDFAAWRAALERA 315
                 89************************************************************************************97 PP

>> PH  PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.1   0.0     1e-09   4.6e-06       2     104 ..     225     316 ..     224     317 .. 0.85

  Alignments for each domain:
  == domain 1  score: 27.1 bits;  conditional E-value: 1e-09
                 EEEEEEEEETSSSSCSEEEEEEEEETTE..EEEESSTTCTTESSEEEEEESTTEEEEEEECTTSSSSTSEEEEEESTSSSTEEEEEEESSHHHHHHHHH CS
          PH   2 vkeGwLlkkgsgkkkswkkrwfvLkdse..llyykndksekdkepkgsislsncevvevvatedpkrkfcfelriverngsrtyllqasseeerkeWik 98 
                 v+ G+L+k++ ++  +w +r+f L+ ++  l+yy ++    ++ ++g i+ls + v           +  +++  +  +g + ++l+a ++++  +W +
  EEA19670.1 225 VHTGILQKRRRKRHQGWARRFFSLDYTSstLSYYHDR---NSSALRGAIPLSLAAVAA------NADRREISI--D--SGAEIWHLRAINQSDFAAWRA 310
                 68899**99999999**********55567*******...****************94......344444455..3..346****************** PP

                 HHHHHH CS
          PH  99 aiqsai 104
                 a+++a+
  EEA19670.1 311 ALERAS 316
                 ***997 PP

>> PH_11  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.4    0.0001      0.45       4      48 ..     229     277 ..     226     315 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.0001
       PH_11   4 ylkkkgsk...aWkrrwf.avlkdgvLeyYksekkkvvkhviklSngse 48 
                  l+k++ k   +W rr+f      + L+yY++ +   ++  i lS   +
  EEA19670.1 229 ILQKRRRKrhqGWARRFFsLDYTSSTLSYYHDRNSSALRGAIPLSLAAV 277
                 55666666678*******3334566*******99999888777776554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1012 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       636  (0.0354733); expected 358.6 (0.02)
Passed bias filter:                      474  (0.0264376); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.73u 0.28s 00:00:01.01 Elapsed: 00:00:00.43
# Mc/sec: 7002.72
//
Query:       EEA19671.1  [L=567]
Description: hypothetical protein PMAA_004500 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
       0.94    9.5   7.5        5.9    7.0   1.8    2.7  2  zf-BED     BED zinc finger
       0.98    9.2   4.9       0.28   11.0   0.2    2.5  3  HeLo       Prion-inhibition and propagation


Domain annotation for each model (and alignments):
>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   1.8   0.00066       5.9      12      43 ..     405     436 ..     399     437 .. 0.91
   2 ?    5.0   0.4    0.0028        25       7      43 ..     446     481 ..     440     482 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.00066
                 GGSS--EETTTTEE----SSTHHHHHHHHHS- CS
      zf-BED  12 lkeqkavCryCgkilsrgggttnLkrHLrrkH 43 
                 + +++++C  C     + +g + L+rH++r+H
  EEA19671.1 405 RSRTRTYCHLCSDHPEGFRGEHELRRHIERAH 436
                 56899*******999999************** PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.0028
                 S----GGSS--EETTTTEE----SSTHHHHHHHHHS- CS
      zf-BED   7 ftpvslkeqkavCryCgkilsrgggttnLkrHLrrkH 43 
                 +++ + k+  a C+ C++  ++     n  +HLrr H
  EEA19671.1 446 VDISPDKNILANCKACKNGKKYE-AMYNAAAHLRRVH 481
                 566666777799******99998.***********99 PP

>> HeLo  Prion-inhibition and propagation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.2   3.2e-05      0.28       9     104 ..      31     125 ..      29     195 .. 0.78
   2 ?   -3.0   0.0      0.61   5.5e+03     168     186 ..     222     240 ..     220     241 .. 0.82
   3 ?   -2.9   0.1      0.56   5.1e+03     108     155 ..     349     375 ..     325     408 .. 0.59

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 3.2e-05
                 HHHHHHHHHHTTTTEEEBGGGGGGH.HHHHHHHHHHHHHHHHHHHHHTTT...-SHH.......HHHHHHHHHHHHHHHHHHHHHHHHHHHH--CGG CS
        HeLo   9 laqlFsgcvkgfellsaarnlgkdy.ellrlkLdieqlRLlqWgeavgllspdsdkrlddestrralvleileqiealleefeklqeryglklekqd 104
                 +a+l++ c k + +l   ++l++d  +++   L+  +  L+ W++  g+++ + d+ l++++  +++ le l qi+++l +  +l+ r+  +++k+d
  EEA19671.1  31 IADLYTECTKFYLMLLKRASLDRDLpQHIYRGLESSYSSLVLWAQGYGVADGNLDELLKKSRLLQSMTLEPLIQISETLRN--RLHPRFASRMHKND 125
                 699*********************94556677*****************84444444444444466777778888888877..67777777666655 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.61
                 HHHHHHHTTT-H..HHHHH CS
        HeLo 168 lvdsLeeLlpasqqqrvqr 186
                 +vd+L++ +p ++q+ +q+
  EEA19671.1 222 FVDYLHQKFPLAHQDLIQQ 240
                 89********887877776 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 0.56
                 ....G-B--GGGS-HHHHHHH.HHHHHHHHHS----S-----EEE-SH CS
        HeLo 108 sslalssereksfraefellkrlmrkaakkrqkrtslpkrlrWaivdk 155
                 +s++ls+ r+++ ++++ + +                      +++dk
  EEA19671.1 349 ISNNLSQYRKDNKSSAYTKKD---------------------LVLHDK 375
                 444444444444444444333.....................333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (567 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       615  (0.034302); expected 358.6 (0.02)
Passed bias filter:                      462  (0.0257683); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.48
# Mc/sec: 3588.23
//
Query:       EEA19672.1  [L=603]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
  ------ inclusion threshold ------
        4.9    7.9   8.8       0.23   12.2   1.0    2.7  3  Occludin_ELL  Occludin homology domain


Domain annotation for each model (and alignments):
>> Occludin_ELL  Occludin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.2       0.3   5.4e+03      19      39 ..      27      47 ..      21      55 .. 0.70
   2 ?   12.2   1.0   1.3e-05      0.23      22     100 ..      98     181 ..      89     182 .. 0.77
   3 ?    3.0   1.1    0.0094   1.7e+02      24      90 ..     156     221 ..     151     222 .. 0.76

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.3
  Occludin_ELL 19 keYkeYkelhaeleevskkfs 39
                  +++k+Y++  + l  ++++f+
    EEA19672.1 27 AQFKTYRQYSRVLLRLNRQFE 47
                  567777777777777777776 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 1.3e-05
  Occludin_ELL  22 keYkelhaeleevskkfseLerelkelkegsk.....eykkieeeilqeykklkkdpeyqekkkrceyLkekLshiKklikeyd 100
                   k+Y ++ + +ee+ +k++eL++el++++         +++ + ++i++  k   k++ y +  + ++  ++ L+ ++k++ke++
    EEA19672.1  98 KNYDTCLRIVEEIDEKLTELSTELSRFDSIPAqrqdiTTQARLNRIQSAIKMSFKKSGYEQLIEALRMANADLQILRKHLKEFQ 181
                   47999999*************888877654442225677777778888888888888888888888888888888888888887 PP

  == domain 3  score: 3.0 bits;  conditional E-value: 0.0094
  Occludin_ELL  24 YkelhaeleevskkfseLerelkelkegskeykkieeeilqeykklkkdpeyqekkkrceyLkekLs 90 
                   Y +l + l+ ++++++ L+++lke+++   +y++ ++   ++ ++ ++ ++y + ++  + L+e L+
    EEA19672.1 156 YEQLIEALRMANADLQILRKHLKEFQKP-PRYQDSASISRRKKRRREECTQYESIRHVSRALHEALT 221
                   99999999999***********999554.55666555434555556668899999999999998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (603 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       863  (0.0481343); expected 358.6 (0.02)
Passed bias filter:                      557  (0.031067); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.26s 00:00:00.85 Elapsed: 00:00:00.42
# Mc/sec: 4271.94
//
Query:       EEA19673.1  [L=1457]
Description: transcription elongation factor SPT6, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.8e-88  293.7   0.0    2.5e-87  291.8   0.0    2.0  1  SH2_2        SH2 domain
    7.3e-37  126.3   0.7    7.3e-37  126.3   0.7    2.2  2  HTH_44       Helix-turn-helix DNA-binding domain of SPT6
    1.8e-27   95.7   0.0    4.1e-27   94.6   0.0    1.6  1  HHH_7        Helix-hairpin-helix motif
    1.4e-22   80.1   0.0    1.1e-21   77.1   0.0    2.6  2  YqgF         Holliday-junction resolvase-like of SPT6
    1.1e-14   54.8  12.1    1.1e-14   54.8  12.1    7.2  7  SPT6_acidic  Acidic N-terminal SPT6
    1.2e-07   32.5   3.6      4e-06   27.6   3.6    3.3  1  HHH_9        HHH domain
    5.4e-06   26.4   0.0    1.4e-05   25.1   0.0    1.8  1  SH2          SH2 domain
     0.0003   21.0   0.0    0.00077   19.7   0.0    1.8  1  HHH_3        Helix-hairpin-helix motif
  ------ inclusion threshold ------
      0.083   12.6   7.1        0.1   12.3   0.0    3.9  4  Tex_N        Tex-like protein N-terminal domain


Domain annotation for each model (and alignments):
>> SH2_2  SH2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  291.8   0.0   1.2e-90   2.5e-87       2     215 ..    1231    1440 ..    1230    1441 .. 0.94

  Alignments for each domain:
  == domain 1  score: 291.8 bits;  conditional E-value: 1.2e-90
       SH2_2    2 ydeeaeeedlkkeeekkkkeekkrkkyvkRvikHpnFknvsaeeaeellaskerGdvviRPSskgedhLtvtwkvadgvyqhidvlEedkenefslg 98  
                  +d+++e+ed ++  ++k+k +++r     RvikHp+F+  ++++aee+l  ++rGd+viRPSskg+dhLtvtwkvad vyqhidvlE dkene+s+g
  EEA19673.1 1231 WDDRQEQED-RELLQEKAK-TESR---FVRVIKHPLFRAYNSKQAEEYLGGMNRGDCVIRPSSKGPDHLTVTWKVADSVYQHIDVLELDKENEYSVG 1322
                  999999999.444333333.3444...45******************************************************************** PP

       SH2_2   99 ktLiigk.eeyeDLDeliarhvepmakkveellahekfkkgskeeveelLreekkanpkrsvYafslskkkpgkflLsflankkarveheyvkvipe 194 
                  + L+ig+ ++y+DLDeli++hv+ ma+kv+e+++hek+++g+k+++e++L+++++anpkrsvYaf++++k+pg+f+L+f+a ++a +++++vkvip+
  EEA19673.1 1323 RILKIGGkYTYSDLDELIVSHVQTMARKVDEMMSHEKYQSGTKADTEKWLTTYTMANPKRSVYAFCINPKYPGYFFLCFKAGQNAALQSWNVKVIPQ 1419
                  *****9989**************************************************************************************** PP

       SH2_2  195 gfklrkqefddvkaLlnwFKk 215 
                  gf+l+++ ++d++aL+n+FK 
  EEA19673.1 1420 GFELQRNPYPDMRALCNGFKL 1440
                  ********************6 PP

>> HTH_44  Helix-turn-helix DNA-binding domain of SPT6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.1       3.1   6.2e+03      45      86 ..      86     127 ..      64     136 .. 0.72
   2 !  126.3   0.7   3.7e-40   7.3e-37       4     112 ..     307     430 ..     305     436 .. 0.96

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 3.1
                 HHHTS---HHHHHHH-GGGSB-SSTTS-....B--HHHHHHH CS
      HTH_44  45 FlvkdelEvPfifqhRkdyllhaekeekkaeklLneddLwri 86 
                 F+v ++ E+   ++ R++    +++e++++e +L+++dL  i
  EEA19673.1  86 FIVDEDEEIEERAERRRERKKRRREEREREEIVLDQEDLELI 127
                 555555555555666777776677777788889999998555 PP

  == domain 2  score: 126.3 bits;  conditional E-value: 3.7e-40
                 --HHHHHHHHHHHHHHHHHHH---SS.---HHHHHHHHHHHHHHHTS---HHHHHHH-GGGSB-SSTTS-..................B--HHHHHHHH CS
      HTH_44   4 ltdeeleeeaeWiakkllkekqesle.eleeefkeavkkvleFlvkdelEvPfifqhRkdyllhaekeek..............kaeklLneddLwriv 87 
                 l+dee++eea Wi++ +l +kq+ +e +l+e+f++av+kvleF+v+d++EvPfifqhRkdyl+ha k                 +a+klLn++dLw+i+
  EEA19673.1 307 LSDEEFHEEAVWISNLMLLRKQHVIEdNLQEPFQRAVAKVLEFMVTDDFEVPFIFQHRKDYLIHAAKVPAspdpgnpdapefviRAQKLLNMNDLWDIF 405
                 79*******************99887799**************************************9999**************************** PP

                 HHHHHHHHHHHHHHHHHHHHHCC-- CS
      HTH_44  88 eldikfrsllekrnaleklyeklkv 112
                 e+d+kfr+ ++kr++l+k+y++l+ 
  EEA19673.1 406 EHDLKFRAYIDKRHTLQKTYDRLQE 430
                 **********************985 PP

>> HHH_7  Helix-hairpin-helix motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.6   0.0   2.1e-30   4.1e-27       1     104 []     907    1014 ..     907    1014 .. 0.94

  Alignments for each domain:
  == domain 1  score: 94.6 bits;  conditional E-value: 2.1e-30
                  HHHHTS---TTGGGS-HHHHHHHHHHHHHHHHHHH-EEHHHHCT-HHHHGGGGGSTT--HHHHHHHHHHHHHC-S----TTHHHHTT....SS-HHH CS
       HHH_7    1 edvlslsfhPlqellskeellkaletalvdivnlvgvdvnkavankyeaallkyiaGlGprkatdllkklkrlnerlearsqlitkq....ilskkv 93  
                  +d++s++f P q +l+++ + k le+alvd+vnl gvd+n+av+++ +++ll+y++GlGprka +l+k+++ +++ +++r +l+  +     ++ kv
  EEA19673.1  907 KDLVSIQFTPGQRYLAEDIVAKQLESALVDMVNLCGVDINEAVSDPATQNLLQYVCGLGPRKASHLVKIVNMNGGIVNNRVELLGVEaqypAMGVKV 1003
                  599********************************************************************************875422336***** PP

                  HHHHCCCEE-- CS
       HHH_7   94 flncagflkid 104 
                  + nca+fl++d
  EEA19673.1 1004 WNNCASFLYLD 1014
                  ********975 PP

>> YqgF  Holliday-junction resolvase-like of SPT6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0         4   7.9e+03       5      53 ..     213     259 ..     211     266 .. 0.52
   2 !   77.1   0.0   5.7e-25   1.1e-21       2     149 ..     738     905 ..     737     906 .. 0.76

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 4
                 --EEEEE-TT--TTS-EEEEEE-TTS-EEEEEEE-S-TT-SS-SHHHHH CS
        YqgF   5 ikvLgvafgkgrsddaiicvlvngeGevvdslklaareedrekkakfve 53 
                 i+ L+++ + g  d+  +  +    G+ +d l   + e + e++++ +e
  EEA19673.1 213 ISGLAISEATGL-DENALEDMRAAFGDGTDYLFALEME-EDEEEQQEEE 259
                 555666666666.5555566666678888776443333.3333333333 PP

  == domain 2  score: 77.1 bits;  conditional E-value: 5.7e-25
                 -----EEEEE-TT--..TTS-EEEEEE-TTS-EEEEEEE-S.-TT-SS-SH...HHHHHHHHHHHHH--SEEEE--SSTHHHHHHHHHHHHHHHTTB.. CS
        YqgF   2 gkiikvLgvafgkgr..sddaiicvlvngeGevvdslklaa.reedrekka...kfvetlkkfllskkPdvigvsGenrdaqkliedvkevlhekeq.. 92 
                 g++++vL+ ++g++   +d+ i  v+v++eG + ++ k+a+ +  d e+     ++v ++ +++++  Pdvi+vsG +++++kl++ + + + +k+   
  EEA19673.1 738 GTVPRVLAFSNGDAPvnGDHFIHWVWVEEEGRPQENGKFAKlQIGDLERGIpdgEDVAAFVELVRRRVPDVIAVSGRSPETRKLYKLLCDLVDRKDLra 836
                 799**********97779*************9998887743133455555400144444555677788******************9999999887411 PP

                 ...........-TTS-B--EEE---TTHHHHHTSHHHHHHSTT--.HHHHHHHHHHHHHH-HHHHHHCS CS
        YqgF  93 ...........dsrlstvgvilvddevailYqnskkaeaefrdkP.pllkyavalaRkiqdPLleyaql 149
                            ++  + ++vi+v+de a lY ns++a+ +f+ k   l  y+  +aR++q+PL eya+l
  EEA19673.1 837 apytvgegkeaKEVADRLEVIMVNDETAQLYANSERATVDFPVKQnYLTSYCCGIARYLQNPLKEYAAL 905
                 2222221111123345678***********************77516889*****************98 PP

>> SPT6_acidic  Acidic N-terminal SPT6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   1.0         2   4.1e+03      22      33 ..      14      25 ..       4      37 .. 0.58
   2 ?    1.1   6.9       0.3     6e+02       1      17 [.      43      59 ..      43      63 .. 0.74
   3 !   54.8  12.1   5.4e-18   1.1e-14      15      88 ..      81     151 ..      78     152 .. 0.76
   4 ?   -6.4  15.2         9   1.8e+04      10      62 ..     175     229 ..     162     241 .. 0.50
   5 ?   -8.9  11.8         9   1.8e+04      26      41 ..     250     261 ..     219     312 .. 0.60
   6 ?   -2.8   0.4       5.1     1e+04      53      63 ..    1044    1054 ..    1025    1069 .. 0.74
   7 ?    1.4   1.4      0.24   4.8e+02      46      74 ..    1226    1252 ..    1208    1259 .. 0.68

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 2
  SPT6_acidic 22 vdddeeeeeeee 33
                 +d++++ee +ee
   EEA19673.1 14 DDEENDEEFDEE 25
                 333333332222 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.3
  SPT6_acidic  1 DssEEedddeeeerkvr 17
                 DssEE+d++ee+e++ r
   EEA19673.1 43 DSSEEDDEEEEDEEAAR 59
                 89999887777776644 PP

  == domain 3  score: 54.8 bits;  conditional E-value: 5.4e-18
  SPT6_acidic  15 kvregFIvdddeeeeeeeeseeeeekkrrkkkkkrreeeedaLdedDldLieentgvkvkrkk.kkfkRlkraed 88 
                  +vregFIvd+dee ee+ e+    +++r+k+++++re+ee  Ld++Dl+Li e++   + +++ +kfkRlkr+++
   EEA19673.1  81 QVREGFIVDEDEEIEERAER----RRERKKRRREEREREEIVLDQEDLELIGEQNPDFQPQSTeSKFKRLKRGHK 151
                  689*******9998886553....22222223333335668**************998887777********996 PP

  == domain 4  score: -6.4 bits;  conditional E-value: 9
  SPT6_acidic  10 eeeerkvregFIvddd.eeeeeeeeseeeeekkrrkkkkkrre...eeedaLdedDl 62 
                    +  ++ ++FI +d+  +ee++ ++++ee  +  +k  +      +e+  Lde+ l
   EEA19673.1 175 HRRRDEEMDDFIEEDEfSDEERQRREDDEEIAHPVRKGIS--GlaiSEATGLDENAL 229
                  3455677899**9997644344333333333333333222..133445566666655 PP

  == domain 5  score: -8.9 bits;  conditional E-value: 9
  SPT6_acidic  26 eeeeeeeeseeeeekk 41 
                  e+eee++    eee+k
   EEA19673.1 250 EDEEEQQ----EEETK 261
                  1111111....11122 PP

  == domain 6  score: -2.8 bits;  conditional E-value: 5.1
  SPT6_acidic   53 eedaLdedDld 63  
                   ++ +Lde+D++
   EEA19673.1 1044 DALELDEEDIK 1054
                   34578888864 PP

  == domain 7  score: 1.4 bits;  conditional E-value: 0.24
  SPT6_acidic   46 kkkrreeeedaLdedDldLieentgvkvk 74  
                   k++   e +d+ +++D +L++e++ ++++
   EEA19673.1 1226 KHRG--EWDDRQEQEDRELLQEKAKTESR 1252
                   2222..456899**********9887654 PP

>> HHH_9  HHH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.6   3.6     2e-09     4e-06       1      68 [.    1023    1115 ..    1023    1117 .. 0.50

  Alignments for each domain:
  == domain 1  score: 27.6 bits;  conditional E-value: 2e-09
       HHH_9    1 npLDnTavHPEsYalakkllkk.lgldlkelige......eallkkl............dkkklaeeevgep...........tleDIleeLakPgr 67  
                  +pLDnT vHPE Y++a+k++++ l+ld +++++e       a ++kl              +++ae     +           tle I +eL++P  
  EEA19673.1 1023 DPLDNTRVHPEDYDIARKMAADaLELDEEDIKAEtdesgpGAIVRKLlkddlqdrvndlILEEYAE-----QleknlnqrkraTLETIRAELQQPYE 1114
                  69*****************88645666665544422222223344442222222222111222222.....01222222233377777777777765 PP

       HHH_9   68 D 68  
                   
  EEA19673.1 1115 E 1115
                  5 PP

>> SH2  SH2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1   0.0   7.2e-09   1.4e-05       7      77 .]    1266    1343 ..    1261    1343 .. 0.88

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 7.2e-09
                  HHHHHHHHHHTTSSTTEEEEEEESSSTTEEEEEEEETT.EEEEEEEEEETTS.......EEEEETTEEESSHHHHHHHH CS
         SH2    7 srkeaerlLleekkdGtFLvReSeskpGdytlsvvedg.kvkhykiqsteng.......kyyiteeekfsslaeLvehY 77  
                  + k+ae++L   +++G+ ++R S++ p+++t++++  +   +h+++ +++++        + i ++ ++s+l+eL+  +
  EEA19673.1 1266 NSKQAEEYLGG-MNRGDCVIRPSSKGPDHLTVTWKVADsVYQHIDVLELDKEneysvgrILKIGGKYTYSDLDELIVSH 1343
                  557*******9.**********************99886789********999999987778889999******99765 PP

>> HHH_3  Helix-hairpin-helix motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.0   3.9e-07   0.00077       2      50 ..     939     993 ..     938    1012 .. 0.76

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 3.9e-07
       HHH_3   2 navgvdiNt.....AsaeeLqklpGlgpklAknIvayReknG.pfksreeLlkvk 50 
                 n  gvdiN      A+  +Lq++ Glgp++A  +v+  + nG  +++r eLl v+
  EEA19673.1 939 NLCGVDINEavsdpATQNLLQYVCGLGPRKASHLVKIVNMNGgIVNNRVELLGVE 993
                 667899998333335899***********************658999****9875 PP

>> Tex_N  Tex-like protein N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0      0.49   9.8e+02      11      34 ..     342     366 ..     334     370 .. 0.79
   2 ?    0.1   0.2      0.27   5.4e+02      62      94 ..     422     454 ..     392     461 .. 0.68
   3 ?   12.3   0.0   5.2e-05       0.1     126     178 ..     542     595 ..     521     598 .. 0.82
   4 ?   -0.8   0.6      0.53   1.1e+03      48      71 ..    1084    1108 ..    1067    1120 .. 0.64

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.49
       Tex_N  11 qveavve.LldegatvPFIARYRke 34 
                  v++v+e ++ ++  vPFI   Rk+
  EEA19673.1 342 AVAKVLEfMVTDDFEVPFIFQHRKD 366
                 56677772456899*********98 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.27
       Tex_N  62 eevlksieeqgklteeLkkkieaaktleeledl 94 
                 ++  + ++e g  +e + + + aa+t+eel+d+
  EEA19673.1 422 QKTYDRLQEIGVKDEIVDEMLAAATTMEELQDV 454
                 445566778888888888888888888888886 PP

  == domain 3  score: 12.3 bits;  conditional E-value: 5.2e-05
       Tex_N 126 sl.aeeeaakyvnkevksaeealegardIiaeeisedaelrkklrellkkegvi 178
                 ++ +ee a + ++ + +++++al+ a++  +ee+ +++++rk +re+++++gv+
  EEA19673.1 542 EKpPEELADTALDTDYSNSTSALRAAKAMFVEELVMNPRMRKVIREQCYRNGVV 595
                 3336788999999**************************************987 PP

  == domain 4  score: -0.8 bits;  conditional E-value: 0.53
       Tex_N   48 eerleyl.relekrkeevlksieeq 71  
                  ee  e+l ++l++rk + l++i+++
  EEA19673.1 1084 EEYAEQLeKNLNQRKRATLETIRAE 1108
                  3333444579999999999999844 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1457 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1171  (0.0653132); expected 358.6 (0.02)
Passed bias filter:                      505  (0.0281667); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 1.03u 0.28s 00:00:01.31 Elapsed: 00:00:00.47
# Mc/sec: 9292.31
//
Query:       EEA19674.1  [L=559]
Description: MAP kinase kinase Ste7 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.2e-63  213.6   0.0    4.2e-63  213.2   0.0    1.1  1  Pkinase         Protein kinase domain
      3e-34  118.5   0.0    4.3e-34  118.0   0.0    1.2  1  Pkinase_Tyr     Protein tyrosine kinase
    3.5e-06   26.1   0.4    1.1e-05   24.4   0.0    1.8  2  Pkinase_fungal  Fungal protein kinase
    0.00081   18.8   0.0     0.0014   18.0   0.0    1.3  1  Kinase-like     Kinase-like
  ------ inclusion threshold ------
       0.02   14.0   0.0       0.03   13.4   0.0    1.1  1  Seadorna_VP7    Seadornavirus VP7
      0.042   13.4   0.0       0.11   12.1   0.0    1.6  1  RIO1            RIO1 family
      0.044   12.7   0.0      0.044   12.7   0.0    1.8  2  Haspin_kinase   Haspin like kinase domain
      0.064   13.2   0.0       0.24   11.3   0.0    1.9  2  APH             Phosphotransferase enzyme family


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  213.2   0.0   1.9e-66   4.2e-63       3     262 ..      69     331 ..      67     333 .. 0.91

  Alignments for each domain:
  == domain 1  score: 213.2 bits;  conditional E-value: 1.9e-66
                 EEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHSCTTB--EEEEEEE.SSEEEEEEE--TTEBHHHHHHHHSS--HHHH CS
     Pkinase   3 kleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklkhpnivrlyevfee.kdelylvleyveggeladllerkgslseeea 100
                 +l+++G G+ G+V k+++++t+  +A K+i+++ +++ + k++lrE+++ + +++p+iv++y++f++ +++++l++ey+++g+l+++ ++ g +  + +
  EEA19674.1  69 TLKEVGAGNGGTVAKVMHATTKVVMARKIIRVDVKENIR-KQILRELQVGHDCNSPYIVTFYGAFQNeSRDIVLCMEYMDCGSLDRISKEFGPVRIDVL 166
                 6799****************************9988877.69***********************99567899****************9999****** PP

                 HHHHHHHHHHHHHHH.HTTEE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCSBCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHHHHHSS-STT CS
     Pkinase 101 kkiakqilegleylH.skgiiHrDlKpeNiLidekgelKitDFGlakelessskltsfvgtseYlAPEvlkeneyskkvDvWslGvilyelltgkppfs 198
                  ki+++il+gl yl+ +++i+HrD+Kp+N+L++++g++K++DFG+a+e  +s  +++fvgts+Y+APE +++  y+  +DvWs+G++++el  g+ pf 
  EEA19674.1 167 GKITESILAGLVYLYeNHRIMHRDIKPSNVLVNSRGNIKLCDFGVATETVNSV-ADTFVGTSTYMAPERIQGGAYTVRSDVWSVGLTVMELAVGRFPFD 264
                 ***************6667********************************99.********************************************* PP

                 TSSHHHHHHHHHHT...HHHHHHHCTSHH...HHHTTS-HHHHHHHHHHT-SSGCCSTTHHHHHTSG CS
     Pkinase 199 gekgkekvekeldq...lekilkilgetkeklpeaseiseeakdllkkllkkdpkkRltaeellqhp 262
                 ++++    ++ +     l  +++i++e   klp+ + +++ + +++ k+l k+ ++R+t +el +++
  EEA19674.1 265 ATDSAAGDRASAGPmgiLDLLQQIVHEPAPKLPKSDAFPPILHEFVAKCLLKKSEERPTPRELYDKD 331
                 76665544444333334555666666889999999**************************998765 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.0   0.0   1.9e-37   4.3e-34       3     256 ..      69     328 ..      67     330 .. 0.88

  Alignments for each domain:
  == domain 1  score: 118.0 bits;  conditional E-value: 1.9e-37
                  EEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS-BTTB--EEEEEE.SSSSEEEEEE--TTEBHHHHHHHTCTTT CS
  Pkinase_Tyr   3 lgkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkklkhpnivkllgvct.keepllivteyvkgGdLlkfLrkkekek 99 
                  + k++G+G+ G+V +        +++v  a K+++ + +e+ ++++l+e+++ ++++ p iv ++g+   +++ +++ +ey++ G+L+   ++    +
   EEA19674.1  69 TLKEVGAGNGGTVAKVMHA----TTKVVMARKIIRVDVKENIRKQILRELQVGHDCNSPYIVTFYGAFQnESRDIVLCMEYMDCGSLDRISKE--FGP 160
                  67899*******9988777....88999999**************************************67777*************987655..6** PP

                  SBHHHHHHHHHHHHHHHHHHHHTT.EEEST-SGGGEEEEETTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSEEEHHHHHHHHHHHHH CS
  Pkinase_Tyr 100 ltlkdllsfalqvAkGmeyLeskk.lvHrdlaarNvLlsenkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekkftsksDvWsfGvllw 196
                  ++++ l +++  + +G+ yL +++ ++Hrd+   NvL++++  +k++DfG+a ++      +++++      +mapE ++ + +t++sDvWs G +++
   EEA19674.1 161 VRIDVLGKITESILAGLVYLYENHrIMHRDIKPSNVLVNSRGNIKLCDFGVATET----VNSVADTFVGTSTYMAPERIQGGAYTVRSDVWSVGLTVM 254
                  ********************7665399**************************99....4556666778899************************** PP

                  HHHTTSSGTTTTSHHHH.............HHHHH..HTTEES-BBTTSBHHHHHHHHHHT-SSGGGS--HHHHH CS
  Pkinase_Tyr 197 Eiftlgespypglknee.............vlekl..kegkrlekpekcpeelyelmkkcweedpeeRptfselv 256
                  E++  g+ p+   +++              +l+++  +   +l+k +  p+ l+e++ kc+ ++ eeRpt +el 
   EEA19674.1 255 ELAV-GRFPFDATDSAAgdrasagpmgildLLQQIvhEPAPKLPKSDAFPPILHEFVAKCLLKKSEERPTPRELY 328
                  **98.****66665555556666666666677777555567899999**********************988875 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4   0.0     5e-09   1.1e-05     316     399 ..     174     248 ..     164     249 .. 0.89
   2 ?   -1.5   0.5      0.36     8e+02     247     277 ..     428     461 ..     336     498 .. 0.64

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 5e-09
  Pkinase_fungal 316 IkghrsLflkagiLHrDiSenNilitdskkegerkglLiDLDlakelsddssesgarertGTleFmaievlkgeeHsyrhDLES 399
                     ++g+  L+++ +i+HrDi   N+l++     ++ +  L D+ +a+e+ +    s+a + +GT  +ma e ++g+  ++r D+ S
      EEA19674.1 174 LAGLVYLYENHRIMHRDIKPSNVLVN-----SRGNIKLCDFGVATETVN----SVADTFVGTSTYMAPERIQGGAYTVRSDVWS 248
                     567889********************.....678899*********994....77889**************999999999866 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.36
  Pkinase_fungal 247 e..lsskaevklkksesskkvekrsvdssv.sts 277
                     +  +s+++  +++++ ++++++++s +s++ ++s
      EEA19674.1 428 HipTSHHGDYSNHNQYAQQQPQHASHNSRSsQSS 461
                     1333333333333333333333333333332222 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   6.3e-07    0.0014     161     257 ..     182     270 ..     164     288 .. 0.78

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 6.3e-07
  Kinase-like 161 qakglvhgkftvdnllldekgglmlggftaLvragtkvvlsevekgfaPpEllgsrggytrknktkmthkldaWqlGlviyriwclklPltlateea 257
                   ++ ++h ++++ n+l + +g ++l +f+         v ++v+ +f    +  +  +    +   +t   d+W +Gl++  ++    P++   + a
   EEA19674.1 182 ENHRIMHRDIKPSNVLVNSRGNIKLCDFGVATET----V-NSVADTFVGTSTYMAPER---IQGGAYTVRSDVWSVGLTVMELAVGRFPFDATDSAA 270
                  46789***********************965444....4.555555544443333222...2346799**********************9887765 PP

>> Seadorna_VP7  Seadornavirus VP7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   1.4e-05      0.03     145     198 ..     171     219 ..     160     229 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 1.4e-05
  Seadorna_VP7 145 niivaglkdLmdfhsestnllhGDcnpenlmcDknGylklvDPvsLlertvvyv 198
                     i+agl  L + h     ++h D++p+n++ ++ G++kl D +   ++tv+ v
    EEA19674.1 171 ESILAGLVYLYENH----RIMHRDIKPSNVLVNSRGNIKLCDFGV-ATETVNSV 219
                   45677777776666....89**********************875.45556655 PP

>> RIO1  RIO1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   4.8e-05      0.11     106     162 ..     165     222 ..     135     225 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 4.8e-05
                 HHHHHHHHHHHHHHHHHHTSTEEESS-STTSEEEETT.EEEE--GTTEEETTSTTHHH CS
        RIO1 106 eaeelyeevleemrklykeaglvHaDLSeyNvlvded.kvviIDvsQaveldhpnale 162
                  + ++ e +l+ +  ly+++++ H D+   Nvlv++  ++ + D++ a+e+ +  a +
  EEA19674.1 165 VLGKITESILAGLVYLYENHRIMHRDIKPSNVLVNSRgNIKLCDFGVATETVNSVADT 222
                 55678899999***********************9988*******9999987776665 PP

>> Haspin_kinase  Haspin like kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0     2e-05     0.044     219     254 ..     177     212 ..      44     222 .. 0.86
   2 ?   -6.1   2.8         8   1.8e+04      10      35 ..     453     478 ..     444     483 .. 0.61

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2e-05
  Haspin_kinase 219 LyvaEtkfeFEHRdLhldniLvdknlnvtlidlkls 254
                    L    ++ +  HRd++  n+Lv++ +n+ l+d+ ++
     EEA19674.1 177 LVYLYENHRIMHRDIKPSNVLVNSRGNIKLCDFGVA 212
                    44455567788*********************9776 PP

  == domain 2  score: -6.1 bits;  conditional E-value: 8
  Haspin_kinase  10 lksrssqsslkhktshssLqkfssss 35 
                     +srssqss ++++   sL+++s  s
     EEA19674.1 453 HNSRSSQSSSRQQSPYLSLEHLSLES 478
                    35666666666666666666665554 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00011      0.24     163     194 ..     181     210 ..     150     214 .. 0.76
   2 ?   -2.0   0.0       1.2   2.7e+03     167     177 ..     431     441 ..     367     447 .. 0.67

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00011
                 SS-EEEE-SS-SGGGEEEC..TTEEEEE---T CS
         APH 163 elptvllHgDlhpgNllvdpddgrvtGviDfe 194
                  + ++++H+D++p N+lv+++++    + Df+
  EEA19674.1 181 YENHRIMHRDIKPSNVLVNSRGNIK--LCDFG 210
                 57789**************665544..66666 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.2
                 EEE-SS-SGGG CS
         APH 167 vllHgDlhpgN 177
                 +  HgD++ +N
  EEA19674.1 431 TSHHGDYSNHN 441
                 44599999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (559 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       734  (0.0409393); expected 358.6 (0.02)
Passed bias filter:                      389  (0.0216967); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.60u 0.31s 00:00:00.90 Elapsed: 00:00:00.47
# Mc/sec: 3539.24
//
Query:       EEA19675.1  [L=340]
Description: lipase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.1e-63  213.4   0.0    4.1e-63  213.1   0.0    1.1  1  Abhydrolase_3    alpha/beta hydrolase fold
    1.2e-09   37.7   0.1    3.5e-09   36.1   0.1    1.6  1  COesterase       Carboxylesterase family
    0.00035   21.2   0.1    0.00058   20.5   0.1    1.3  1  Abhydrolase_6    Alpha/beta hydrolase family
    0.00096   18.1   0.0     0.0015   17.5   0.0    1.5  1  Say1_Mug180      Steryl acetyl hydrolase
     0.0035   16.3   0.0     0.0048   15.8   0.0    1.2  1  Chlorophyllase2  Chlorophyllase enzyme
     0.0096   15.0   0.0      0.014   14.5   0.0    1.1  1  Chlorophyllase   Chlorophyllase
     0.0097   15.4   0.9      0.044   13.3   0.2    2.2  2  Peptidase_S9     Prolyl oligopeptidase family


Domain annotation for each model (and alignments):
>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  213.1   0.0   1.6e-66   4.1e-63       1     210 [.      98     316 ..      98     317 .. 0.89

  Alignments for each domain:
  == domain 1  score: 213.1 bits;  conditional E-value: 1.6e-66
                    EEEE--STTTS--TTTTHHHHHHHHHHHTSEEEEEE---TTTS-TTHHHHHHHHHHHHHHHTHH..HHTETTC.EEEEEEETHHHHHHHHHHHHHH CS
  Abhydrolase_3   1 lvyfHGGGfvlgsldthdalcrelakelgavvvsvdYrlAPehpfPaavedalaalrwlaeqaw..elgadps.rivlaGdSaGGnlaaavalrar 93 
                    ++y+HGGG+vlg+++t++++c++++k++g+vvv vdYrlAPe+pfPaav+d+++al wl++ +   +l+++p+ ++ ++G SaGGnlaa ++++a 
     EEA19675.1  98 MLYLHGGGWVLGNINTENTVCTNICKRAGIVVVTVDYRLAPENPFPAAVHDCWEALIWLHTPSTitHLNINPKsKLSVGGSSAGGNLAAILTHKAL 193
                    79***********************************************************9954588888765******************8887 PP

                    HT..T---EEEEEEESE-SSTSSTTSHHHHHCHHT.TTSSSSCHHHHHHHHHHHSS.GGGGGSTTTSGGGC..S-..SST---EEEEEETT-TTHH CS
  Abhydrolase_3  94 de..gepkvagqvliyPvtdlertesesikkaeel.adgplltraaldlfwrlylp.eadrddplasplla..ed..lsglpptlvvvaefDplrd 181
                     e  g++++++q+l  Pvtd   t s++ + a ++ + +++l++ ++ ++ ++ylp e+++ +p aspll   ed  +++lpp++vvv+e D+lr 
     EEA19675.1 194 LErpGKINIVAQALSVPVTDN--TASPENNWAWKEfEFTAALPALKMMWYRKHYLPdEKEWGNPEASPLLYsnEDghWAKLPPAVVVVGELDVLRG 287
                    76234777***********77..4444444444444888999*************88************99532489******************* PP

                    HHHHHHHHHHHTT--EEEEEETTEETTGG CS
  Abhydrolase_3 182 egeayaerlraagvevelieyegmvHgfa 210
                    ege ya++l+++gv++e+++++gm+H f+
     EEA19675.1 288 EGEGYAKKLQENGVKAEVHVMKGMPHPFL 316
                    **************************996 PP

>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.1   0.1   1.4e-12   3.5e-09      91     204 ..      82     190 ..      78     205 .. 0.86

  Alignments for each domain:
  == domain 1  score: 36.1 bits;  conditional E-value: 1.4e-12
                 EEEEESSSSSTTSSEEEEEEE--STTTS-BGCG..S-THHHHHHHTSEEEEE----HHHHH-B-SSTTSBS-HHHHHHHHHHHHHHH..HGGGGTEEEE CS
  COesterase  91 nvytPkekkeakkklPVlVwihGggfqtgsase..ydgsaLaaegnvivVtinYRlGvlGFlstgdeeapGNvGllDqvlALrWVke..nIasFGGdpe 185
                  v+tP+e +  + ++ V+ ++hGgg + g  ++    +++++++ +++vVt+ YRl +         e p  +++ D   AL W+++  +I + + +p+
  EEA19675.1  82 RVFTPEE-PAPEGGYGVMLYLHGGGWVLGNINTenTVCTNICKRAGIVVVTVDYRLAP---------ENPFPAAVHDCWEALIWLHTpsTITHLNINPK 170
                 69***87.6888888***************98878999******************86.........55666789999999999985448999999997 PP

                 .EEEEEEETHHHHHHHHHHH CS
  COesterase 186 .rvtlfGesAGaasvsllll 204
                  +  + G+sAG+ ++++l+ 
  EEA19675.1 171 sKLSVGGSSAGGNLAAILTH 190
                 35899999999999998875 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5   0.1   2.3e-07   0.00058       3     214 ..     100     318 ..      98     326 .. 0.54

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 2.3e-07
                    EE--GC.....G...CHHHH........HHHHCCTCEEEEE--TTS.T..S-GGCS--HHHCHHH..HHHHCCTT...TTSE.EEEEETCHHHHHH CS
  Abhydrolase_6   3 llHGagssassW...lvapL........aallaagvhvlapDlpGh.G..rsdpppldledladl..aalldelaa.gggpv.vlvGHSlGGalal 80 
                     lHG+g     W       +            +ag+ v+++D++      ++   ++ +e+l  l    ++++l          + G S GG la+
     EEA19675.1 100 YLHGGG-----WvlgN---IntentvctNICKRAGIVVVTVDYRLApEnpFPAAVHDCWEALIWLhtPSTITHLNInPKS-KlSVGGSSAGGNLAA 186
                    589988.....95431...3333233432222333677999998331111223333444333222224455555433344.36************* PP

                    HHHHCC..........EE.EEES-..----TTTS----TTHHHHHH..TT-CCCCHCCHS-HSCCCCHHHCCCCHCHCCCGHHHHCCHHCHTTCCH CS
  Abhydrolase_6  81 aaapla........lvvg.vlldppptalpagllaaalelllalla..llrllawlsreplprlfladedadaawrarlarlaallaglgllpaaa 165
                     + + a         +v+  l  p   +++ +  +   + ++ +    +l++l ++    +++++l+   ++ +w+ + a ++ + + +g     +
     EEA19675.1 187 ILTHKAllerpgkiNIVAqALSVP---VTDNTASPENNWAWKEFEFtaALPALKMMW---YRKHYLP---DEKEWGNPEASPLLYSNEDG-----H 268
                    *77777565444331122233333...333333333333333222211222233333...5558888...78999999999999999999.....* PP

                    HTT-TTGCEEECTT-C......HHHHCHHCCCH.STTEEETCE...SSS-HHHHSH CS
  Abhydrolase_6 166 wadlpvpllvlggeDp......lvprllerlla.qagarlpvvlpgaGHlphleep 214
                    wa lp++++v+g+ D        +   +++l     +a++ +v++g  H p+l + 
     EEA19675.1 269 WAKLPPAVVVVGELDVlrgegeGY---AKKLQEnGVKAEV-HVMKGMPH-PFL-AM 318
                    ********8889888866543322...3333334457777.88888886.333.33 PP

>> Say1_Mug180  Steryl acetyl hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   0.0   5.8e-07    0.0015     113     212 ..      84     188 ..      64     303 .. 0.79

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 5.8e-07
  Say1_Mug180 113 v.petfdPkvD.pvllylHGGgfalklipvtlvfLsnlrklfpdmailvsDYtvtaakdqskkYplqvleslavydylvk..skgfknvv......vl 200
                    pe+  P+    v+lylHGGg++l+ i +   + +n+ k    + ++ +DY +       + +p  v ++     +l    +++  n++      v 
   EEA19675.1  84 FtPEEPAPEGGyGVMLYLHGGGWVLGNINTENTVCTNICKRA-GIVVVTVDYRLAP----ENPFPAAVHDCWEALIWLHTpsTITHLNINpksklsVG 176
                  4477777777768*************************9986.5678899**9988....67788888888765555554114444444333333378 PP

  Say1_Mug180 201 GdSaGGnlvLsl 212
                  G SaGGnl   l
   EEA19675.1 177 GSSAGGNLAAIL 188
                  999999985433 PP

>> Chlorophyllase2  Chlorophyllase enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   1.9e-06    0.0048       8     110 ..      83     191 ..      76     221 .. 0.70

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 1.9e-06
  Chlorophyllase2   8 vvaPte...ageYpvllflhGyl..lln.slYsqlLkhiash.gfivvapqlykvaeada.keiksaakvlnWlakgLesvlp.eevepdlskl 92 
                      v++P+e   +g Y v+l+lhG    l n +  +++ ++i    g +vv +      e+   + ++   + l Wl++   s+++  +++p+ skl
       EEA19675.1  83 VFTPEEpapEGGYGVMLYLHGGGwvLGNiNTENTVCTNICKRaGIVVVTVDYRLAPENPFpAAVHDCWEALIWLHTP--STIThLNINPK-SKL 173
                      66655433389*********866534331445678888886516666666655555555579************886..33442678886.89* PP

  Chlorophyllase2  93 alsgHSrGgktafalalg 110
                      ++ g S+Gg+ a+ l+ +
       EEA19675.1 174 SVGGSSAGGNLAAILTHK 191
                      **********99887754 PP

>> Chlorophyllase  Chlorophyllase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.0   5.3e-06     0.014      20     136 ..      68     187 ..      57     204 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 5.3e-06
  Chlorophyllase  20 tvdsssrsspapPkpl.iivtPae...aGtypvvlflhG..tllsnkfy.skllnhiashGfivvaPqlykllp.PsaqdeidsaaevieWlseg 106
                     +   ++r ++  P+ l ++ tP e   +G y v+l+lhG  ++l n +   ++   i+    ivv    y+l+p       ++++ e + Wl + 
      EEA19675.1  68 A---VKRVETQGPDVLvRVFTPEEpapEGGYGVMLYLHGggWVLGNINTeNTVCTNICKRAGIVVVTVDYRLAPeNPFPAAVHDCWEALIWLHTP 159
                     3...466666667665268887665449**********6447999966516788999999999999999****9633456788888989999765 PP

  Chlorophyllase 107 lkavlptsveanlsklalvGhsrGGktafa 136
                       +    ++++  skl++ G s GG+ a  
      EEA19675.1 160 S-TITHLNINP-KSKLSVGGSSAGGNLAAI 187
                     3.333345555.478999999999987754 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       1.8   4.7e+03      10      23 ..     122     135 ..     119     136 .. 0.84
   2 !   13.3   0.2   1.7e-05     0.044      63     188 ..     170     315 ..     146     337 .. 0.76

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 1.8
                   HHCCT-EEEEE--T CS
  Peptidase_S9  10 ladrGyvvvvanir 23 
                   +  +G+vvv +++r
    EEA19675.1 122 CKRAGIVVVTVDYR 135
                   5679********98 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 1.7e-05
                   GGGEEEEEETHHHHHHH....HHHHH-GGG-SEEE..EESE---CCCHHCSTTSTHH.HCCCC--TTTCHHHHHHHHHH-CGGG--........... CS
  Peptidase_S9  63 serlaitGgSyGGyltg....aalnqrpdlFkaav..aevpvvdvlrydsdtdllte.eymewgnpeeneegykelspyspldnvk........... 141
                   +++l + G S+GG l++     al +rp +   ++   +vpv+d++++  ++  +++ e+++ +++    +++++++ y p ++ +           
    EEA19675.1 170 KSKLSVGGSSAGGNLAAilthKALLERPGKINIVAqaLSVPVTDNTASPENN--WAWkEFEF-TAALPALKMMWYRKHYLPDEK-Ewgnpeasplly 262
                   6789999999999765411116777788877765411578999999888886..55533333.333446777777777777555.447777777888 PP

                   ........---EEEEEEETT-SSS-THHHHHHHHHHH--S-SEEEEEETTS-SST CS
  Peptidase_S9 142 ........aypplLlihGlaDdrvppaealklvaaLqkkgknvlllifpdegHgv 188
                           + pp  +++G++D  v   e++ ++++Lq++g++++++++++  H +
    EEA19675.1 263 snedghwaKLPPAVVVVGELD--VLRGEGEGYAKKLQENGVKAEVHVMKGMPHPF 315
                   8889999999**********9..777***********************999954 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (340 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       292  (0.0162865); expected 358.6 (0.02)
Passed bias filter:                      277  (0.0154498); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.50u 0.29s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 2296.91
//
Query:       EEA19676.1  [L=128]
Description: L-PSP endoribonuclease family protein Brt1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      2e-39  134.4   0.0    2.2e-39  134.2   0.0    1.0  1  Ribonuc_L-PSP  Endoribonuclease L-PSP


Domain annotation for each model (and alignments):
>> Ribonuc_L-PSP  Endoribonuclease L-PSP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  134.2   0.0   1.2e-43   2.2e-39       3     120 ..      11     127 ..       9     128 .] 0.96

  Alignments for each domain:
  == domain 1  score: 134.2 bits;  conditional E-value: 1.2e-43
                    TSTTTS.SS-BSEEEETTEEEEEEE-SB-TTTSCB.-SSHHHHHHHHHHHHHHHHHHTT--GGGEEEEEEEESSGGGHHHHHHHHHHHSSSSTS-- CS
  Ribonuc_L-PSP   3 aapaaa.apYsqavkagnlvyvsGqlpldpetgelvegdveeqtrqalenlkavLaaagaslsdvVkvtvFladiedfaevnevyaeafdelkeaP 97 
                    +ap+++ + Ysqa+ a+++vy+sG +++dpetg+lv+gd+++ t+q+++nl  vL+aag+s+++vVkv+vFl ++++fa++n+vy+++  + k  P
     EEA19676.1  11 KAPKPLpGIYSQAIIANGVVYCSGAVAMDPETGKLVDGDIKAHTHQCIKNLTHVLEAAGTSIDKVVKVNVFLDNMDNFADMNSVYTQYWGDVK--P 104
                    667665367***********************************************************************************8..* PP

                    EEEEEE-SBSGGG-SEEEEEEEE CS
  Ribonuc_L-PSP  98 arsaveVaaLpkgakvEIeaiav 120
                     r++v+V++Lp + +vEIe+iav
     EEA19676.1 105 SRTCVAVKTLPLNTDVEIECIAV 127
                    **********************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (128 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       624  (0.0348039); expected 358.6 (0.02)
Passed bias filter:                      503  (0.0280551); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.31s 00:00:00.78 Elapsed: 00:00:00.49
# Mc/sec: 778.47
//
Query:       EEA19677.1  [L=775]
Description: krueppel c2h2-type zinc finger protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-46  158.7   0.3    2.6e-46  157.8   0.3    1.4  1  Fungal_trans  Fungal specific transcription factor domain
    7.6e-07   29.3   9.4    0.00036   20.8   1.1    2.9  2  zf-C2H2       Zinc finger, C2H2 type
    2.7e-05   24.4   1.8    2.7e-05   24.4   1.8    2.8  3  zf-H2C2_2     Zinc-finger double domain
     0.0011   19.6   0.6     0.0011   19.6   0.6    3.3  3  zf-C2H2_4     C2H2-type zinc finger
  ------ inclusion threshold ------
       0.17   12.3   2.5       0.22   12.0   0.1    2.4  3  nlz1          NocA-like zinc-finger protein 1


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  157.8   0.3   7.2e-50   2.6e-46       2     265 ..     300     573 ..     299     575 .. 0.95

  Alignments for each domain:
  == domain 1  score: 157.8 bits;  conditional E-value: 7.2e-50
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLl 98 
                   d++f+n+hp+fpilhk++++p +          +spl+++ai+ lG+++s+++ ++        s  +i++ lr+ i+  +df +p+s lw +q+Ll
    EEA19677.1 300 DLYFENYHPHFPILHKQTLDPVK----------TSPLMVAAIVTLGSTLSGDAVHWH------AS-IKIHDTLRYLIFGTPDFDPPAS-LWCVQTLL 378
                   89*********************..........***********************6......33.6788999***************.******** PP

  Fungal_trans  99 llelyektssdralher...hhgvavr.larslgLhrnpsyvgkks...lwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcd 188
                   +l+  ek++s+r++h +   +hg  ++ + r +  +      g++    +w++w+e  +   R++++ F++D ++++++G++ +l+ ++++lpLPc 
    EEA19677.1 379 ILQAHEKMFSTRKHHQLahiFHGAIITlMKRGVAYQNTAQTPGTTPleqSWHRWIE-MQGSNRTAFFGFIMDAQHSFMFGHTCILSVHDVRLPLPCA 474
                   ***************************999999999888777755599********.5555************************************ PP

  Fungal_trans 189 dddlwesddaseetlvetklsneeksrkiasfllaLkkilsk...............iagsllsiekqlqqrdlq...............seklswv 255
                   d  lw+  +a+ ++++       +k ++ + fl  Lk++l+                ++g l+s+  +l+ rd++               +  + w+
    EEA19677.1 475 DV-LWDCMKAEDWDRMM------RKTPESPGFLPVLKRLLARtpipphcsayarfilLHG-LFSVTAHLKARDSVtlgvgrmptansprlDAIDTWK 563
                   **.*************8......9********************************7777.************************************ PP

  Fungal_trans 256 eeleraldnW 265
                   e+lera+d+W
    EEA19677.1 564 ETLERAMDTW 573
                   ********** PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   1.8   6.6e-05      0.24       1      23 []       5      29 ..       5      29 .. 0.94
   2 !   20.8   1.1   9.9e-08   0.00036       1      23 []      35      57 ..      35      57 .. 0.97

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 6.6e-05
                EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCp..dCgksFkrksnLkrHirtH 23
                + C+  +Cgk+F r ++L rH+  H
  EEA19677.1  5 HSCTepGCGKRFLRAEHLARHRLNH 29
                679999****************998 PP

  == domain 2  score: 20.8 bits;  conditional E-value: 9.9e-08
                EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCpdCgksFkrksnLkrHirtH 23
                y+Cp C+k+F r+++L+rH  +H
  EEA19677.1 35 YQCPSCPKRFVRRDLLRRHEERH 57
                9******************9999 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1         1   3.8e+03      15      25 ..       5      17 ..       2      18 .. 0.69
   2 !   24.4   1.8   7.5e-09   2.7e-05       1      26 []      21      46 ..      21      46 .. 0.94
   3 ?   -3.6   0.5         5   1.8e+04       6      10 ..     389     393 ..     380     394 .. 0.55

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 1
   zf-H2C2_2 15 yeCp..lCdkaFk 25
                + C    C+k+F 
  EEA19677.1  5 HSCTepGCGKRFL 17
                5566547****96 PP

  == domain 2  score: 24.4 bits;  conditional E-value: 7.5e-09
   zf-H2C2_2  1 nLrrHirkHtgekpyeCplCdkaFkt 26
                +L rH  +H ++ +y+Cp+C+k+F++
  EEA19677.1 21 HLARHRLNHSPKQIYQCPSCPKRFVR 46
                699*********************85 PP

  == domain 3  score: -3.6 bits;  conditional E-value: 5
   zf-H2C2_2   6 irkHt 10 
                 +rkH+
  EEA19677.1 389 TRKHH 393
                 58988 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.4   1.6    0.0006       2.1       3      23 ..       7      29 ..       5      30 .. 0.88
   2 !   19.6   0.6   3.1e-07    0.0011       1      23 [.      35      57 ..      35      58 .. 0.96
   3 ?   -3.0   1.1         5   1.8e+04       8      23 ..     385     397 ..     383     398 .. 0.68

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0006
   zf-C2H2_4  3 Cpi..CgksFsskkaLlrHlkth 23
                C+   Cgk+F + ++L rH ++h
  EEA19677.1  7 CTEpgCGKRFLRAEHLARHRLNH 29
                77777****************99 PP

  == domain 2  score: 19.6 bits;  conditional E-value: 3.1e-07
   zf-C2H2_4  1 fkCpiCgksFsskkaLlrHlkth 23
                ++Cp C+k+F +++ L+rH ++h
  EEA19677.1 35 YQCPSCPKRFVRRDLLRRHEERH 57
                89*******************99 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 5
   zf-C2H2_4   8 ksFsskkaLlrHlkth 23 
                 k Fs++k+   H ++h
  EEA19677.1 385 KMFSTRKH---HQLAH 397
                 56777777...66666 PP

>> nlz1  NocA-like zinc-finger protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.1       2.1   7.6e+03      36      55 ..     211     230 ..     210     231 .. 0.83
   2 ?   12.0   0.1   6.1e-05      0.22       2      47 ..     288     337 ..     287     342 .. 0.74
   3 ?   -2.4   0.0       1.8   6.6e+03      37      55 ..     532     554 ..     530     555 .. 0.73

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 2.1
        nlz1  36 vgaqlaaslGvsGkkagsSP 55 
                 ++a l ++ G++G ++ +SP
  EEA19677.1 211 LSADLNTTGGSAGIPSITSP 230
                 57888889999999999998 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 6.1e-05
        nlz1   2 sisypgslaGa....YAgYPqqF.lphGvtLDptKsssLvgaqlaaslGvs 47 
                 s  yp+ laG     +  Y ++F + h  tLDp K+s L+ a +  +lG++
  EEA19677.1 288 SFFYPSKLAGFwdlyFENYHPHFpILHKQTLDPVKTSPLMVAAIV-TLGST 337
                 67799999997222134667777667899*********9988666.89975 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 1.8
        nlz1  37 gaqlaa....slGvsGkkagsSP 55 
                 +a l a    +lGv   +++ SP
  EEA19677.1 532 TAHLKArdsvTLGVGRMPTANSP 554
                 56666666679999777888888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (775 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       500  (0.0278878); expected 358.6 (0.02)
Passed bias filter:                      436  (0.0243181); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.66u 0.31s 00:00:00.97 Elapsed: 00:00:00.48
# Mc/sec: 4882.25
//
Query:       EEA19678.1  [L=356]
Description: hypothetical protein PMAA_004570 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    0.00024   20.9   1.7    0.00073   19.4   1.7    1.8  1  F-box-like  F-box-like
     0.0061   16.4   3.9      0.013   15.3   1.9    2.5  2  F-box       F-box domain
     0.0073   16.5   2.2      0.015   15.4   2.2    1.5  1  DUF1033     Protein of unknown function (DUF1033)


Domain annotation for each model (and alignments):
>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   1.7   1.2e-07   0.00073       4      35 ..       7      38 ..       4      45 .. 0.91

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 1.2e-07
  F-box-like  4 LPdEiLlqIFsyLppsdLlrlalVCrrWrrva 35
                LP E+L  I+syLp +d+ +l+l+C    r+a
  EEA19678.1  7 LPVELLDLILSYLPNRDIKSLRLTCLTLSRLA 38
                9************************8888887 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   1.9   2.2e-06     0.013       6      34 ..       7      35 ..       4      40 .. 0.88
   2 ?   -0.6   0.0      0.22   1.3e+03      15      23 ..     249     257 ..     249     271 .. 0.67

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 2.2e-06
                S-HHHHHHHHHTS-HHHHHHHCTT-HHHH CS
       F-box  6 LPsevlrhILerLplsdllalrrVSkgwr 34
                LP e+l  IL++Lp +d+ +lr+++ ++ 
  EEA19678.1  7 LPVELLDLILSYLPNRDIKSLRLTCLTLS 35
                9************************6665 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.22
                 HHTS-HHHH CS
       F-box  15 LerLplsdl 23 
                 L++L+++d+
  EEA19678.1 249 LSHLDFMDR 257
                 89*****93 PP

>> DUF1033  Protein of unknown function (DUF1033)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   2.2   2.6e-06     0.015      13      55 ..     111     153 ..     106     174 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 2.6e-06
     DUF1033  13 PWWflegWeediveekefdefeealkyykkeWqklkeeyksik 55 
                 PWWf e +ee+++++++ ++f+ea    + +W+  ++  ++ k
  EEA19678.1 111 PWWFEESYEENVKNRRSQETFQEADPSIHVSWEFYQQLIQQQK 153
                 9*************************99999986665444433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (356 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       472  (0.0263261); expected 358.6 (0.02)
Passed bias filter:                      355  (0.0198003); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.67u 0.34s 00:00:01.01 Elapsed: 00:00:00.58
# Mc/sec: 1844.29
//
Query:       EEA19679.1  [L=493]
Description: cation diffusion facilitator, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.5e-25   90.2   8.2    1.9e-25   89.8   8.2    1.2  1  Cation_efflux  Cation efflux family
    4.4e-08   33.1   0.0      1e-07   32.0   0.0    1.5  1  ZT_dimer       Dimerisation domain of Zinc Transporter


Domain annotation for each model (and alignments):
>> Cation_efflux  Cation efflux family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.8   8.2   2.1e-29   1.9e-25       2     198 ..     208     398 ..     207     399 .. 0.91

  Alignments for each domain:
  == domain 1  score: 89.8 bits;  conditional E-value: 2.1e-29
  Cation_efflux   2 ilsllanlilalvelivglltnSlalladafhslsdlvsllllllalklsrkppderfpfGygrlevlgalvsgllllglavfllleaiqklikeg 97 
                    +++l+anlil++++++v l+t S+++la  + + +d++s+ +++ + +l+ +  + rfp G++rle+lg l+ +++++   +++ + +iq+l +e+
     EEA19679.1 208 YVNLIANLILLIAKIVVTLMTSSVSVLASLVDAALDFLSTAIVWSTTRLTGRRDKFRFPVGRQRLEPLGVLIFSVVMITSFFQVGILSIQRLADED 303
                    689***********************************************7777***************************************555 PP

  Cation_efflux  98 er.eihaglalvvalvslvvnlalllilrragrklrsaalkaaalhvlgDaltslgvlvsalvillfnlksgplaDpvaslligliilysalkllk 192
                       ++ +  al++++  ++++ ++++ +rr     ++++++a a+++++D++ +   +v  lv  + n     ++Dp+++l+++++++ ++ +++ 
     EEA19679.1 304 DTlVELTVPALIIMASTVAIKGLCWIWCRRI----NNSNVQALAQDAMTDVVFNTFSIVFPLVGTFANSR---YFDPLGGLFLSCYVIGNWAGTAS 392
                    5505556778899999999999999999987....9****************999999999999998666...7****************999999 PP

  Cation_efflux 193 eslseL 198
                    e +  L
     EEA19679.1 393 EHIAHL 398
                    887765 PP

>> ZT_dimer  Dimerisation domain of Zinc Transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.0   0.0   1.1e-11     1e-07      18      77 ..     421     480 ..     405     481 .. 0.90

  Alignments for each domain:
  == domain 1  score: 32.0 bits;  conditional E-value: 1.1e-11
                 S-EEEEEEEEE-S----EEEEEEEE-TTS-HHHHHHHHHHHHHHHHHH-TT--EEEEEEE CS
    ZT_dimer  18 gvkgvhdlrtrksGskifvdlhievdgdlsvkeaHeiadevekrikeefpgvadvliHve 77 
                  ++ +++l + +sG+++ v+++i++dg++s++++H+i + ++  +++ + +v + ++H++
  EEA19679.1 421 CIRWIQNLEAYYSGDRLNVEVDIVLDGHTSLHDSHDIGESLQYMLESTVANVDRAFVHLD 480
                 477789999*************************************************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (493 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       756  (0.0421663); expected 358.6 (0.02)
Passed bias filter:                      494  (0.0275531); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.74u 0.37s 00:00:01.10 Elapsed: 00:00:00.58
# Mc/sec: 2577.92
//
Query:       EEA19680.1  [L=1106]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        2.4    8.4   7.0        2.3    8.5   3.3    2.9  2  XhlA      Haemolysin XhlA


Domain annotation for each model (and alignments):
>> XhlA  Haemolysin XhlA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.1      0.12   2.2e+03      21      46 ..     455     480 ..     448     483 .. 0.79
   2 ?    8.5   3.3   0.00013       2.3       7      48 ..     487     530 ..     481     532 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.12
        XhlA  21 dkleekaaeaeekiknleedlkkles 46 
                 ++l+e  + ++ + ++l ++l +l++
  EEA19680.1 455 QRLDEQLDQVQGQRESLRNQLQQLQQ 480
                 36888888888888999999988886 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00013
        XhlA   7 erietkldnlee..rvdkleekaaeaeekiknleedlkklesnq 48 
                  r+++++ ++e+  ++ +l + ++  e+++ +l ++l+k+ +++
  EEA19680.1 487 LRLDEQVQEHEQleELRRLGQQERHIEQRLRELRHQLEKIRDTL 530
                 58899999999999899***********************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1106 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2600  (0.145016); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                       133  (0.00741815); expected 17.9 (0.001)
Passed Fwd filter:                        41  (0.0022868); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 1.78u 0.44s 00:00:02.22 Elapsed: 00:00:00.63
# Mc/sec: 5273.31
//
Query:       EEA19681.1  [L=564]
Description: 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.2e-46  158.0   0.0    4.5e-46  157.5   0.0    1.2  1  HMGL-like  HMGL-like
    3.7e-23   82.1   0.0    6.7e-23   81.3   0.0    1.4  1  ECH_1      Enoyl-CoA hydratase/isomerase
    2.5e-19   70.0   0.0    3.9e-19   69.3   0.0    1.3  1  ECH_2      Enoyl-CoA hydratase/isomerase


Domain annotation for each model (and alignments):
>> HMGL-like  HMGL-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  157.5   0.0   7.5e-50   4.5e-46       2     263 ..       9     290 ..       8     291 .. 0.93

  Alignments for each domain:
  == domain 1  score: 157.5 bits;  conditional E-value: 7.5e-50
                 -EEEE-TTTHHHHTSSS---HHHHHHHHHHHHHHT-SEE--TSGGGT.T..HHHHHHHS---TT-B............--EE-SSHHHHHHHHH....T CS
   HMGL-like   2 vkivdttLRDGeqalkaalsveeklaiakaLdeagvdeiEvgfpaased..dfevvraiakavkkar..........ilalvrarekdikaavealkga 88 
                 v+iv++ +RDG q++k+a+ +e k ++++ L +ag+++iE++  +++ +  +++++++i +++ + +           l++++++ k ++ a +     
  EEA19681.1   9 VRIVEVGPRDGLQSIKDAVPTETKTELIQRLWRAGLRSIELTSIVSTRKvpQLADCQEILNNPAIRSltedseasglRLPVLTPNLKGLDIALS----R 103
                 89***************************************6666664333788999999999888455556778888999*************....* PP

                 T-SEEEEEEES-HHHHHHHHSSTHHHHHHHHHHHHHHHHHTT-E......TTT-BTTTBS--HHHHHHHHHHHHHHT-SEEEEEETTS---HHHHHHHH CS
   HMGL-like  89 gakrvhvfiatselhlkaklkkdreevakkaeeavkaarslgkd......velsledasrtdleflaevveaaeeaGatriniaDtvGvltPneaaeli 181
                 g+k+v vfi+++e + +a+++++ e+ ++ka+++ + a ++g+       + +  ++ + t++  +++ v+++ ++G++++++ Dt G+ tP ++a li
  EEA19681.1 104 GVKEVAVFISATEGFSQANINCSVEQGVEKARAVAQKAIEAGIAvrgyvsCIFVDPYDGPTNPSSVLRCVQELLQMGCYEVSLGDTTGAGTPAKVATLI 202
                 ********************************************99888888888999***************************************** PP

                 HHHHHHS-.GGGEEEEEB-TTS-HHHHHHHHHHTT--EEEEBTTS--......SSBBB-BHHHHHHHHHHTT-B----HHHHHHHHHH CS
   HMGL-like 182 salkervkdkvilsvHcHndlGlAvantlaAveaGadrvdgtvnGlG......eraGnaaleelvaalealgvdtgldlqklrsiaal 263
                 ++l ++      l+ H+H+++G+Avan l A+  G+++ d++v GlG      ++ Gn+++ee+v + +++g++tg++l++l ++ + 
  EEA19681.1 203 RYLEKNGVSLRNLAGHFHDTYGQAVANVLQAYICGIRVFDASVGGLGgcpfapGAKGNVSTEEVVFMFQNAGIQTGVNLEELVATGNW 290
                 ****9988899***********************************************************************999875 PP

>> ECH_1  Enoyl-CoA hydratase/isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.3   0.0   1.1e-26   6.7e-23       7     127 ..     361     484 ..     355     550 .. 0.79

  Alignments for each domain:
  == domain 1  score: 81.3 bits;  conditional E-value: 1.1e-26
                 EEEEE--CGCTTEE-HHHHHHHHHHHHHHHHSTTECEEEEEEBTSEEEEEB-HHHHHHHHCHHHHHHHCCHH...HHHHHHHHSSSEEEEEE-SEEETH CS
       ECH_1   7 aviklnrPeavNalsaelltEliqalekleddksvravvLtGgdkaFaaGadlkemaeeekakqallkeevl...elwtklytvpkpviaavnGaaigG 102
                 ++i+lnrP++ N l+  +lt li+ ++    ++sv  vv+tG + +F+ G  +k    e+ + +a+ +++++   +l++ + + pkpvia +nG+a g+
  EEA19681.1 361 LKITLNRPNKGNMLTRSMLTSLIKCFKAYHHNPSVSRVVITGTGSYFCTGVGMKRGRFENASSAAERNSSFDlliQLFEIIDEYPKPVIACLNGHACGA 459
                 68****************************************************998887644444444443112566677889*************** PP

                 HHHHHHHSSEEEEETTTEEE-GGGG CS
       ECH_1 103 GlelalacDiviaadnasfglnelk 127
                 G+ la acD +i+ ++a + l+ +k
  EEA19681.1 460 GVALAFACDERIIIQTATINLSPTK 484
                 ******************9998766 PP

>> ECH_2  Enoyl-CoA hydratase/isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.3   0.0   6.5e-23   3.9e-19       4     120 ..     363     478 ..     361     484 .. 0.94

  Alignments for each domain:
  == domain 1  score: 69.3 bits;  conditional E-value: 6.5e-23
                 EEE--GGGTT-B-HHHHHHHHHHHHHHCC-TT-SEEEEEESSSSECE--B--HHHHHHHHCS-THHHHHHHHHHHHHHHHHC-SS-EEEEE-BEEETHH CS
       ECH_2   4 itLnrpkalNaLslemvralkealkewekddevklvvlkgagekafCAGgDvralyeaakegkkeeeeffreeYklnyliatypkpvvalmdGivmGgG 102
                 itLnrp++ N L+ +m+++l +++k+++++++v+ vv++g+g   fC G  +++ + ++ ++++e+++ f    +l   i +ypkpv+a ++G + G G
  EEA19681.1 363 ITLNRPNKGNMLTRSMLTSLIKCFKAYHHNPSVSRVVITGTG-SYFCTGVGMKRGRFENASSAAERNSSFDLLIQLFEIIDEYPKPVIACLNGHACGAG 460
                 9***************************************88.9**********99999998878799******************************* PP

                 HHHHTTSSEEEE-TT-EE CS
       ECH_2 103 vGlsvhgsfrvvtertvf 120
                 v+l+  +  r++ +++++
  EEA19681.1 461 VALAFACDERIIIQTATI 478
                 ***********9888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (564 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       427  (0.0238162); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 3638.41
//
Query:       EEA19682.1  [L=495]
Description: MFS monocarboxylate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.6e-20   72.6  53.2    2.8e-20   72.6  49.1    2.0  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.014   15.3   3.2      0.014   15.3   3.2    4.2  4  DUF485    Protein of unknown function, DUF485
       0.13   11.1   1.6        0.2   10.6   1.6    1.1  1  STIL_N    SCL-interrupting locus protein N-terminus


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.6  49.1   4.7e-24   2.8e-20       6     352 ..     113     443 ..     106     444 .. 0.81
   2 !   14.3  12.7   2.4e-06     0.015      67     150 ..     375     462 ..     369     487 .. 0.72

  Alignments for each domain:
  == domain 1  score: 72.6 bits;  conditional E-value: 4.7e-24
       MFS_1   6 flsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrr.vlllglllfalglllll.fasslw.lllvlrvlqGlgaga 101
                 +++++++ +++ ++ ++++++l+  ps+i+++ ++ +++ ++   + Gr +d  G  + ++ +g+++ +l+ l+l+ +++ +w ++l   +++G+g+g+
  EEA19682.1 113 IVNTWGYVNAFGVFQSYYTTQLQELPSTISWIGSVQTFLVFFIGTFSGRATDA-GYFKfTWSCGMVIAVLS-LFLTsLCHEYWqIFLSQGLMSGIGCGL 209
                 566677777888888899**********************************9.65555************.6666477******************** PP

       MFS_1 102 lfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeeekgtgpaplvpaw 200
                 +f   +al+  +f k +r++a++ ++ag++ G ++ p+    l+  +g+ ++   l+++sl  ++ +l++l+++ p+r++             p+v+ w
  EEA19682.1 210 MFCPTIALLPTYFEK-HRALALAGAAAGSATGGLIIPIMVKSLLPKIGFAWTLRCLGFFSLATLLPGLFFLRQRLPPRATG------------PIVE-W 294
                 ***************.**********************************************9664334444444444443............5666.* PP

       MFS_1 201 kallkdpvlwillialllfffgfsg...lltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallav 296
                 +a++  p    +l+ ++++ff++ g    ++++ +++++ lg s +  ++ ll ++++vg++++++ g lsd +    +l+l ++l++++a+  + +a 
  EEA19682.1 295 EAFREVP----YLCFAFGMFFVILGlyvGFFYVSSFARDALGAS-VSASTDLLIVMSAVGLPSRIIPGILSDAFTG--PLNLLIPLAFCTAITAYGWAG 386
                 *******....66666666666666666888888899*******.77777779999***************99554..566666666666555555555 PP

       MFS_1 297 tssavllllvlvliGfglgfv...fpsllalasdlappeeagtasglfntagslggalg 352
                  ss + l++  v++G++ + v   fp +l+ ++d +  +++g  +g + t+ s+g++ g
  EEA19682.1 387 VSSIPGLYVWAVIYGITTAGVqglFPVALSSLTDDL--KKTGVRMGMVLTIVSFGALTG 443
                 556666666677777755555244777777777777..*****************9876 PP

  == domain 2  score: 14.3 bits;  conditional E-value: 2.4e-06
       MFS_1  67 lglllfalglllllfa..sslwlllvlrvlqGlgagalfpagaaliadwfpk.eergraigllsagfslGailgpllggllasslg......W 150
                 +   ++a++ +++ +a  ss++ l+v  v+ G++++++  +  ++++ ++ + ++ g  +g++ + +s+Ga+ g +++g+l+++        +
  EEA19682.1 375 F---CTAIT-AYG-WAgvSSIPGLYVWAVIYGITTAGVQGLFPVALSSLTDDlKKTGVRMGMVLTIVSFGALTGSPIAGALVQADQnrgpgeY 462
                 2...23333.222.34459999************************************************************55444544442 PP

>> DUF485  Protein of unknown function, DUF485
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   2.4      0.26   1.5e+03      19      67 ..     107     155 ..     100     165 .. 0.65
   2 ?   -0.9   0.3      0.28   1.6e+03      22      47 ..     174     202 ..     157     220 .. 0.52
   3 ?   15.3   3.2   2.4e-06     0.014      16      57 ..     305     345 ..     301     355 .. 0.87
   4 ?    0.4   0.1      0.11   6.5e+02      39      69 ..     356     385 ..     352     396 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.26
      DUF485  19 pltaiflvvYfgfvllvafapdllatkvgegnitvglllgllqivltfl 67 
                 +l+ +++v   g+v +++++++  +t++ e   t+ ++  +  ++++f+
  EEA19682.1 107 ILAHFVIVNTWGYVNAFGVFQSYYTTQLQELPSTISWIGSVQTFLVFFI 155
                 4555666666677777777777777777754666666655555555554 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.28
      DUF485  22 aiflvvYfgfv...llvafapdllatkvg 47 
                 + ++++ +++    l+  + + +l++ ++
  EEA19682.1 174 CGMVIAVLSLFltsLCHEYWQIFLSQGLM 202
                 22222222222000334455556666665 PP

  == domain 3  score: 15.3 bits;  conditional E-value: 2.4e-06
      DUF485  16 fafpltaiflvvYfgfvllvafapdllatkvgegnitvglll 57 
                 faf + +++l++Y+gf  +++fa+d l+++v+  ++ + +++
  EEA19682.1 305 FAFGMFFVILGLYVGFFYVSSFARDALGASVS-ASTDLLIVM 345
                 99*****************************9.557766665 PP

  == domain 4  score: 0.4 bits;  conditional E-value: 0.11
      DUF485  39 pdllatkvgegnitvglllgllqivltfllt 69 
                 p++l+  ++ g +++ ++l++   +++   +
  EEA19682.1 356 PGILSDAFT-GPLNLLIPLAFCTAITAYGWA 385
                 677788888.9**********9999887655 PP

>> STIL_N  SCL-interrupting locus protein N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   1.6   3.3e-05       0.2     347     393 ..      14      60 ..       3      63 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 3.3e-05
                 XXXXXXXXXXXXXXXXXXXXXXX--S----SS---XXXXXXXXXXXX CS
      STIL_N 347 ssesaspanklsvsdhdsgveDedlsPrpsPsPhpvsqqvkriePsv 393
                    ++ ++ +l ++ hd + +D++ sP p+Ps +++s + ++++P +
  EEA19682.1  14 VQVDSRQQDELNINQHDNYEKDKQRSPSPTPSAYTTSDNDNELQPTI 60 
                 4445555799**********************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (495 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       736  (0.0410508); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.42
# Mc/sec: 3548.91
//
Query:       EEA19683.1  [L=146]
Description: pterin-4-alpha-carbinolamine dehydratase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.2e-20   72.1   0.0    3.8e-20   71.9   0.0    1.1  1  Pterin_4a  Pterin 4 alpha carbinolamine dehydratase
  ------ inclusion threshold ------
      0.011   15.6   0.0      0.016   15.2   0.0    1.1  1  DUF4957    Domain of unknown function (DUF4957)


Domain annotation for each model (and alignments):
>> Pterin_4a  Pterin 4 alpha carbinolamine dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.9   0.0   4.2e-24   3.8e-20       8      90 ..      44     126 ..      33     127 .. 0.87

  Alignments for each domain:
  == domain 1  score: 71.9 bits;  conditional E-value: 4.2e-24
   Pterin_4a   8 iqkllaelpgWr.leeaeelerefkfkdfeeaiafvnrvaalaeeenHhpdilvsynkvtvrltThdaggltenDfklAakide 90 
                 +q+ll e+++W+ +ee+  +++ + fk+++++++f++ v+  ++++nHh++i+v++++v++++tTh  +glt++D+++A+ +d+
  EEA19683.1  44 LQSLL-EEKQWNlDEEGMGVAKMYYFKTYTKCLDFTQVVGIRSKSKNHHATITVKSGSVRIHWTTHVPRGLTQKDIDMAQYCDQ 126
                 34444.448***6448889***************************************************************97 PP

>> DUF4957  Domain of unknown function (DUF4957)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   0.0   1.8e-06     0.016       3      50 ..      71     120 ..      68     137 .. 0.85

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1.8e-06
     DUF4957   3 Ytlsgeidfskkvtirgvdkanhpkitlgkgnasistga....sLkiknldl 50 
                 Yt  + +df++ v ir+++k+ h++it++ g+++i  ++    +L+ k++d+
  EEA19683.1  71 YT--KCLDFTQVVGIRSKSKNHHATITVKSGSVRIHWTThvprGLTQKDIDM 120
                 44..789****************************98888888888888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (146 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       469  (0.0261587); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 1023.86
//
Query:       EEA19684.1  [L=378]
Description: C6 transcription factor (Fcr1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.5e-08   33.9  12.0      4e-08   33.2  12.0    1.3  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
        6.8    6.6  12.3        9.3    6.1  12.3    1.2  1  TFIIA     Transcription factor IIA, alpha/beta subunit


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.2  12.0   4.5e-12     4e-08       1      36 [.      26      60 ..      26      63 .. 0.89

  Alignments for each domain:
  == domain 1  score: 33.2 bits;  conditional E-value: 4.5e-12
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfyses 36
                +aCd+Cr kK+KCd+  P C++C+  n+ C+f +++
  EEA19684.1 26 KACDRCRLKKSKCDGASP-CGRCRADNAICVFGERK 60
                59****************.************55544 PP

>> TFIIA  Transcription factor IIA, alpha/beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1  12.3     0.001       9.3      53     221 ..     135     330 ..     118     372 .. 0.50

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.001
       TFIIA  53 eeaqspqfvlqlpqslkqalqasaaaasqapastsqslpslvipagksvqslta...nssaataatfslpakleppvqipagvtlqtasgqlykvnvqa 148
                 + +q +q+  q+++ l q + +s       ++  ++s p+ + + +++++s+++       ++++  ++p +++++  + a  +l+++ +  y+ + +a
  EEA19684.1 135 NVEQMQQKLWQQNAGLMQRQESSDG-----SSDIAHSPPTTTLNLNANAHSYHQhrhHHMVNNHSRRHHPYSVSQYADTLARHQLPPTPPGSYSPSSAA 228
                 3344455555555566555543333.....222222233333333333333332233344456677777888888888888888888888888888899 PP

       TFIIA 149 sgaqqiaaqplqqvvqq.......sqgsaaqssvaalqaq.sqqaqalaepqqq.lekq.qqqqqqqqqqqqqqqvqqqqqe................. 220
                 s++qq+ + p+ +  +        + +sa+ + ++ ++++  +++++  +  qq +++   qq+qqq+q+q + +++++  +                 
  EEA19684.1 229 SSQQQMSSLPIIKP-EPllittsaGLSSAIPTPTSTISPNsAPNFST--LLAQQgINPIsLQQHQQQPQPQTPWTTSSNDLNfddldligggsgsgnqf 324
                 99999998888887.32355333333333333333333332222222..22222122112222223333333223333333255555555555444444 PP

       TFIIA 221 .....e 221
                       
  EEA19684.1 325 tplfeD 330
                 444440 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (378 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       916  (0.0510904); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.25s 00:00:00.74 Elapsed: 00:00:00.41
# Mc/sec: 2748.71
//
Query:       EEA19685.1  [L=329]
Description: aldose 1-epimerase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.3e-60  203.6   0.1    5.2e-60  203.3   0.1    1.0  1  Aldose_epim  Aldose 1-epimerase


Domain annotation for each model (and alignments):
>> Aldose_epim  Aldose 1-epimerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  203.3   0.1   2.9e-64   5.2e-60      12     301 .]       6     325 ..       2     325 .. 0.95

  Alignments for each domain:
  == domain 1  score: 203.3 bits;  conditional E-value: 2.9e-64
                  EEEECTCTTEEEEEEETT.STEESB-B-STHHHHHHSC..CSSCEECSS-SEEETTEEE.ETTEEEECCCCBTTTCEETBSGGG...SB-EEEEEEE. CS
  Aldose_epim  12 sakislyGAtllslkvpdkeqrevllgsddaeeylkds..yfgatlgrvanRianGeFe.ldGkpyqlpqneegknplHGgarg...reWeveevke. 102
                    ++  +GA +++++v++   ++++ g+++ e+y+k +  yfgat+gr+anR ++G  e ++G++y+l++ +  +n+lHGg +g   r++e +++ + 
   EEA19685.1   6 AFTFLPLGAIIQEFNVDG---TNIVQGFKTQEDYVKYNapYFGATIGRFANRLKDGLLEnVNGQTYTLEKTN-APNALHGGSKGwdkRIFEGPTTVTr 99 
                  568899************...8**********************************99768***********.*********************9999 PP

                  ..TTEEEEEEEEEEETCHCSTSEEEEEEEEEEETTEE...EEEEEEEEESS...S-EEEEEEEEEEEETSSC.TCTGGEEEEEEEEEEEECTTSGEEE CS
  Aldose_epim 103 ..ddgvtvslvlkpdgeegypgdlevrvtytLnedne...lkieyeatndg...kptpfnltnHtYFnlsge.sidshelqieadeylevdeeliptg 191
                    ++++ +++ + +++eegypg+levrv yt ++++    l+ eyea+  g   ++t +n+tnH+YFn+s   +i +++ ++++d +l++d+++ip g
   EEA19685.1 100 ngKESILFKYLS-KHEEEGYPGTLEVRVWYTASKEDGrtvLETEYEAELVGdevEETAVNITNHSYFNISDGpDITGTKAKLATDWHLPFDSTSIPLG 196
                  999*********.8889***************98887799********99999*****************77************************** PP

                  EEEECTTCCCCCCSSEEHCSSETEEEEEEEESSC............SEEEEEETTTTEEEEEEEETTSSEEEEEECTTTT........SEECCEEESS CS
  Aldose_epim 192 elkdvkgtpfdfrqpkaigedlkglDhayllksk............lkaviidpdkksgiklevsttepalvvytgnflk........kylsreglal 269
                   +   ++ p    +   ++  + ++D+++l +              l++ ++  +++++++lev++tepa+++ytgnf +           +++g+++
   EEA19685.1 197 GMDHFTKVPV--AEQFILQGAQTEIDDCFLMERDpskvpldtrplpLNLLAEFSHDNTKLHLEVYSTEPAFQFYTGNFIDvpavnglpARGKYAGFCV 292
                  *********9..55555544444********99999****************************************************899******* PP

                  ECTCETCCCECHHHT.-EEEHTTTEEEEEEEEE CS
  Aldose_epim 270 etqmlpdepnhpefp.sivlkpGesysaetsys 301
                  e+++++++pn pe++   vlk+Ge y a+++y+
   EEA19685.1 293 EPSRYVNAPNVPEWRnMAVLKKGEIYGAKMVYK 325
                  ***************99*************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (329 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       356  (0.0198561); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 2233.56
//
Query:       EEA19686.1  [L=1717]
Description: hypothetical protein PMAA_004650 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.4e-11   41.8   0.0    1.6e-10   41.0   0.0    1.3  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    1.7e-07   31.4   0.3    5.7e-06   26.5   0.0    2.9  3  rve              Integrase core domain
    0.00023   21.0   0.2    0.00075   19.3   0.2    1.8  1  gag_pre-integrs  GAG-pre-integrase domain
  ------ inclusion threshold ------
       0.15   12.3   0.1        0.8    9.9   0.1    2.3  2  PAC4             Proteasome assembly chaperone 4
       0.88    9.7   8.7       0.47   10.6   0.1    3.6  3  Integrase_H2C2   Integrase zinc binding domain


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.0   0.0   4.6e-14   1.6e-10       7     178 ..    1208    1383 ..    1204    1440 .. 0.81

  Alignments for each domain:
  == domain 1  score: 41.0 bits;  conditional E-value: 4.6e-14
       RVT_2    7 slPkdrkaigsrWvftkkkddlkevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeee.lvvhqldvdsafLnae..ldeevyvkqP 100 
                  + P + +  g r+v   k++  +++  k+rlv+q ++ k ++++  + +P i+ +s rL+l + + ++ +  +  dv  a+++++  l+ e y++ P
  EEA19686.1 1208 DIPLEARIYGFRFVDEVKNKGTDKAFEKSRLVVQAYNDK-DKEFVLTQSPTIQRSSQRLILCIGTSKDgVRFWIRDVTQAYIQSTtkLNREFYIRIP 1303
                  568889999*********9999**************987.567999*****************876651556677*******987336788****** PP

       RVT_2  101 pGfeidreeekvykLnkslyGlkqapllWnekidk.vLkklgferseaesGly.vrgtgegklivalyvddlliagsdik 178 
                  p         +  ++ + lyG+  a+  W+++ ++   ++lg+e s+    l  +    +g  ++++  dd li++++  
  EEA19686.1 1304 PELRHYFPGCEFLRVVRPLYGIPEAGNHWFRTYHEhHTTHLGMETSTYDPCLLhCCDPKQGFGVIGMQTDDTLIVADEAF 1383
                  ****99888999*****************99886615678899999998876515555666689**********998764 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0         3   1.1e+04      71      98 ..     498     529 ..     493     531 .. 0.78
   2 ?    1.4   0.0     0.094   3.4e+02      30      91 ..     757     824 ..     753     829 .. 0.76
   3 !   26.5   0.0   1.6e-09   5.7e-06       7     117 ..     846     949 ..     841     951 .. 0.78

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 3
         rve  71 lsDngseytsk....afrefladlgirvsftr 98 
                 ++D  ++ +      a+ +f++++  ++++ r
  EEA19686.1 498 HTDEERTAARArykpAWDKFIQQYEGTPDMER 529
                 6676666654478889999**99999998876 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.094
         rve  30 vddfsrlilaealsdemdastvlalleravarfggve.......pervlsDngseytskafrefladlg 91 
                 + d+s + ++ +  de++  +++  l+r  +rfg+          +r  +D  +e++ +++ +f+++ +
  EEA19686.1 757 IWDYSLMSYITQSFDEDQCFLTATELRRLHRRFGHPSvgrlhktLLRAGYDTNPEMI-EKINRFCHHCQ 824
                 679999**********55555555555555566655599999888889999999999.88888888865 PP

  == domain 3  score: 26.5 bits;  conditional E-value: 1.6e-09
         rve   7 lwqvDvtvvripdgggkayllvvvddfsrlilaealsdem..dastvlalleravarfggvepervlsDngseytskafrefladlgirvsftrpgrpq 103
                  + vD+++++    g  + +l++vd ++r+  a+ l + +  ++ ++l++l+  ++ + g  p+ +++D g+ ++sk+f+ ++++lg+     ++   +
  EEA19686.1 846 SIIVDIMYIN----G--KPVLHIVDEATRFNAACWLISISarATWDALRMLW--IDTYLGP-PDFIVTDAGKNFVSKEFTHLASSLGTITVSVPVEAHW 935
                 5667888888....3..5688999**99997666555552004444444444..6666666.**************************999999999** PP

         rve 104 dnGkvErfhrtlkd 117
                 + G vEr h  l++
  EEA19686.1 936 SIGAVERYHAVLRR 949
                 *********99987 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.2   2.1e-07   0.00075      22      63 ..     780     824 ..     764     825 .. 0.76

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 2.1e-07
  gag_pre-integrs  22 ssinlWHrRLGHpsfsrlkkLfkkgllpglki..sk.sevCeaCq 63 
                      +++++ HrR+GHps++rl+k   +   + +++  +k +++C++Cq
       EEA19686.1 780 TELRRLHRRFGHPSVGRLHKTLLRAGYDTNPEmiEKiNRFCHHCQ 824
                      678899************9988544444444333555889****9 PP

>> PAC4  Proteasome assembly chaperone 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0       4.7   1.7e+04      27      42 ..     365     380 ..     347     392 .. 0.66
   2 ?    9.9   0.1   0.00022       0.8      32      70 ..     543     583 ..     524     586 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 4.7
        PAC4  27 plgslvvAmpsrtnkk 42 
                 +l++l +++p+  + +
  EEA19686.1 365 KLQDLFYCLPDELQTQ 380
                 5799999999988733 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.00022
        PAC4  32 vvAmpsrtnkktptisTtLlgdg.sde..aserlAqrLArRl 70 
                  +++p+rt+ + pt++T  ++   +d   +s++lA+ LA R 
  EEA19686.1 543 QYSLPDRTK-NEPTTATGYFTVAaTDHneFSSSLASELANRS 583
                 699*****9.7799999999777553355**********995 PP

>> Integrase_H2C2  Integrase zinc binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.1       0.1   3.7e+02      25      42 ..     294     311 ..     292     313 .. 0.86
   2 ?   10.6   0.1   0.00013      0.47      10      53 ..     782     827 ..     777     830 .. 0.89
   3 ?   -0.1   1.0      0.29     1e+03      10      23 ..    1333    1347 ..    1327    1351 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.1
  Integrase_H2C2  25 tlerlrrryyWpgmrkdv 42 
                     +l+ ++  yyW ++++ +
      EEA19686.1 294 MLKDVALSYYWDNIDQWI 311
                     7889999*******9977 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00013
  Integrase_H2C2  10 lkeaHdsagHlGiektlerlrrryy..WpgmrkdvkkyvksCetCq 53 
                     l+++H   gH+++ +  ++l r  y   p m +++++++++C+t  
      EEA19686.1 782 LRRLHRRFGHPSVGRLHKTLLRAGYdtNPEMIEKINRFCHHCQTYG 827
                     899****************99999866799************9875 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.29
  Integrase_H2C2   10 lkeaHds.agHlGie 23  
                      ++ +H++ + HlG+e
      EEA19686.1 1333 FRTYHEHhTTHLGME 1347
                      799**********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1717 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       724  (0.0403815); expected 358.6 (0.02)
Passed bias filter:                      526  (0.0293379); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.93u 0.33s 00:00:01.26 Elapsed: 00:00:00.49
# Mc/sec: 10556.11
//
Query:       EEA19687.1  [L=1452]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.2e-97  319.8  19.9    1.1e-16   61.2   0.0    8.2  7  Ank_2      Ankyrin repeats (3 copies)
    6.5e-75  238.1   1.2    0.00076   19.7   0.0   16.4 16  Ank_3      Ankyrin repeat
    1.3e-73  242.5   3.1    1.1e-09   38.6   0.0   10.8 11  Ank_4      Ankyrin repeats (many copies)
    1.6e-69  227.5   8.8    0.00078   19.8   0.0   15.6 15  Ank        Ankyrin repeat
      4e-65  215.0  11.2    2.9e-05   24.3   0.0   15.3 15  Ank_5      Ankyrin repeats (many copies)
    4.1e-11   42.6   0.0    7.1e-11   41.8   0.0    1.3  1  PNP_UDP_1  Phosphorylase superfamily
     0.0018   18.1   1.3         69    3.1   0.0    5.4  6  DUF1191    Protein of unknown function (DUF1191)
     0.0029   17.5   0.0     0.0068   16.3   0.0    1.6  1  NACHT      NACHT domain
     0.0034   17.2   3.9         56    3.7   0.0    6.8 10  PEGA       PEGA domain


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.3   0.0   4.4e-19   8.7e-16       1      83 []     950    1042 ..     950    1042 .. 0.90
   2 !   51.8   2.2   4.6e-17   9.2e-14       1      83 []    1050    1144 ..    1050    1144 .. 0.84
   3 !   57.3   1.0   8.6e-19   1.7e-15       2      82 ..    1119    1210 ..    1118    1211 .. 0.87
   4 !   38.3   0.0   7.7e-13   1.5e-09      26      83 .]    1215    1279 ..    1208    1279 .. 0.88
   5 !   56.8   0.0   1.2e-18   2.5e-15       1      83 []    1287    1381 ..    1287    1381 .. 0.89
   6 !   58.3   0.0   4.4e-19   8.7e-16       4      83 .]    1324    1415 ..    1324    1415 .. 0.89
   7 !   61.2   0.0   5.5e-20   1.1e-16       1      79 [.    1355    1445 ..    1355    1449 .. 0.87

  Alignments for each domain:
  == domain 1  score: 58.3 bits;  conditional E-value: 4.4e-19
       Ank_2    1 LhlAakngnlelvklLlegadpn..k.ngktaLhyAakngnleivklLleh....ad...ndgrtpLhyAarsghleivklLlekgadinlkd 83  
                  LhlA+k g++++vk Ll  + +n  + ++ taLh+A ++g+++iv+l+l+     +d   ++g tpL +A+ +gh ++v +L+e++adi+++d
  EEA19687.1  950 LHLASKLGYYDIVKSLLGICHVNslDvEDCTALHHASSRGHIDIVSLILKTkgaiVDpfsKSGVTPLWFASANGHDNVVSILIENKADIETTD 1042
                  8*****9999*******667788654789********************9668896677799***************************9987 PP

  == domain 2  score: 51.8 bits;  conditional E-value: 4.6e-17
       Ank_2    1 LhlAakngnlelvklLl.egadpn..k..ngktaLhyAakngnleivklLleh......adnd..grtpLhyAarsghleivklLlekgadinlkd 83  
                  L +Aa++g++++v +L+ ++a+++  +   ++t+L  Aa++g+ ++v+lL+++      + ++  g+tpL  A+++gh +iv lL++++a+i+++d
  EEA19687.1 1050 LLQAALKGHDSVVSILIkNKANLEarNnpHDQTPLLNAAEKGHDNVVSLLIKNqanieaT-DTliGQTPLLKAIENGHDNIVSLLIKNKANIEARD 1144
                  679*****999******87766655524688********************977554422.3366*********************9999*99887 PP

  == domain 3  score: 57.3 bits;  conditional E-value: 8.6e-19
       Ank_2    2 hlAakngnlelvklLl.egadpn..k..ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinlk 82  
                    A++ng++++v lL+ ++a+++  +   ++t+L  Aa++g+ +iv+lLl++       +  g+tpL  Aa++gh+ +v+lL+ +ga+i++k
  EEA19687.1 1119 LKAIENGHDNIVSLLIkNKANIEarDnlHDQTPLLQAAEKGHDNIVSLLLKNkanieaCNPRGQTPLGQAAENGHYSTVELLVRNGANIEAK 1210
                  67999**999******88888777635889********************977565555588*********************99***9987 PP

  == domain 4  score: 38.3 bits;  conditional E-value: 7.7e-13
       Ank_2   26 gktaLhyAakngnleivklLleh......ad.ndgrtpLhyAarsghleivklLlekgadinlkd 83  
                   +t+L  A+++g+  +v++L+ +       d ++g+tpL  Aa++gh+ +v++L  +ga+i+++d
  EEA19687.1 1215 SQTPLCQATEKGHYSVVEFLVRNganieeRDiQYGQTPLCQAAEKGHYSVVEFLTRNGAKIEARD 1279
                  48*******************9885544444999*********************99****9987 PP

  == domain 5  score: 56.8 bits;  conditional E-value: 1.2e-18
       Ank_2    1 LhlAakngnlelvklLl.egadpn..k..ngktaLhyAakngnleivklLleh......ad.ndgrtpLhyAarsghleivklLlekgadinlkd 83  
                  L  Aa+n+++++v++L+ +ga ++  +   g+t+L  Aak+g+  +v++L  +      +d + g+tpL  Aa++gh+ +v++L+ +ga+i+++d
  EEA19687.1 1287 LCKAAENDHYSVVEFLVrNGASIEarDdlYGQTPLCQAAKKGHYSVVEFLTRNganieaIDtRRGQTPLCQAAENGHFSVVEFLVRNGANIEARD 1381
                  5679***999********99998876369**********************9775555544888*********************99****9987 PP

  == domain 6  score: 58.3 bits;  conditional E-value: 4.4e-19
       Ank_2    4 AakngnlelvklLl.egadpn..k..ngktaLhyAakngnleivklLleh.....ad..ndgrtpLhyAarsghleivklLlekgadinlkd 83  
                  Aak+g++++v++L  +ga+++  +   g+t+L  Aa+ng+  +v++L+ +     a+   +g+tpL  Aa++gh+ +v++L+ +ga+i+++d
  EEA19687.1 1324 AAKKGHYSVVEFLTrNGANIEaiDtrRGQTPLCQAAENGHFSVVEFLVRNganieARddLYGQTPLCQAAENGHFSVVEFLVRNGANIEARD 1415
                  8999*99*******999999986368**********************9775555224666*********************99****9987 PP

  == domain 7  score: 61.2 bits;  conditional E-value: 5.5e-20
       Ank_2    1 LhlAakngnlelvklLl.egadpn..k..ngktaLhyAakngnleivklLleh.....ad..ndgrtpLhyAarsghleivklLlekgadi 79  
                  L +Aa+ng++++v++L+ +ga+++  +   g+t+L  Aa+ng+  +v++L+ +     a+   +g+tpL+ Aa +gh+ iv++L+ +g+ +
  EEA19687.1 1355 LCQAAENGHFSVVEFLVrNGANIEarDdlYGQTPLCQAAENGHFSVVEFLVRNganieARddLYGQTPLYQAANKGHYSIVEFLIRNGSRM 1445
                  679***************99999886369**********************9775555224666*********99**********888765 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       7.4   1.5e+04       5      26 ..     740     761 ..     740     762 .. 0.79
   2 !    6.7   0.0    0.0069        14       4      27 ..     948     971 ..     945     973 .. 0.86
   3 !   13.3   0.0   4.6e-05     0.093       3      28 ..     979    1004 ..     977    1006 .. 0.89
   4 !   11.2   0.0   0.00023      0.45       2      30 ..    1012    1039 ..    1011    1040 .. 0.93
   5 !   11.6   0.0   0.00018      0.35       2      29 ..    1046    1072 ..    1045    1074 .. 0.90
   6 !   13.1   0.0   5.7e-05      0.11       2      30 ..    1080    1107 ..    1079    1108 .. 0.91
   7 !   15.5   0.0   9.4e-06     0.019       2      30 ..    1114    1141 ..    1114    1142 .. 0.93
   8 !   14.0   0.0   2.8e-05     0.056       2      30 ..    1148    1175 ..    1147    1176 .. 0.91
   9 !   18.4   0.0   1.1e-06    0.0021       2      30 ..    1181    1208 ..    1180    1209 .. 0.94
  10 !   10.7   0.0   0.00034      0.69       3      29 ..    1216    1241 ..    1214    1243 .. 0.92
  11 !   13.9   0.0   3.2e-05     0.063       1      30 [.    1248    1276 ..    1248    1277 .. 0.93
  12 !   14.9   0.0   1.5e-05     0.029       2      30 ..    1283    1310 ..    1282    1311 .. 0.93
  13 !   15.0   0.0   1.4e-05     0.027       1      30 [.    1316    1344 ..    1316    1345 .. 0.94
  14 !   18.9   0.0   7.3e-07    0.0015       2      30 ..    1351    1378 ..    1350    1379 .. 0.94
  15 !   19.7   0.0   3.8e-07   0.00076       1      30 [.    1384    1412 ..    1384    1413 .. 0.95
  16 !   18.9   0.0     7e-07    0.0014       1      26 [.    1418    1442 ..    1418    1443 .. 0.93

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 7.4
       Ank_3   5 pLhlAarsgnleivkfLlenkg 26 
                 p+ +++r+++ ++ ++L +++g
  EEA19687.1 740 PMDHCVRFAHSSVKQYLTKHRG 761
                 677999******7777777665 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0069
       Ank_3   4 tpLhlAarsgnleivkfLlenkga 27 
                  pLhlA + g ++ivk Ll ++++
  EEA19687.1 948 PPLHLASKLGYYDIVKSLLGICHV 971
                 69*****************96554 PP

  == domain 3  score: 13.3 bits;  conditional E-value: 4.6e-05
       Ank_3    3 etpLhlAarsgnleivkfLlenkgad 28  
                  +t+Lh+A + g+++iv ++l+ kga 
  EEA19687.1  979 CTALHHASSRGHIDIVSLILKTKGAI 1004
                  7********************88875 PP

  == domain 4  score: 11.2 bits;  conditional E-value: 0.00023
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                  G tpL +A  +g+ ++v  L+e + ad+ 
  EEA19687.1 1012 GVTPLWFASANGHDNVVSILIE-NKADIE 1039
                  78********************.8*9985 PP

  == domain 5  score: 11.6 bits;  conditional E-value: 0.00018
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadv 29  
                   +tpL +Aa+ g+ ++v  L++ + a++
  EEA19687.1 1046 DQTPLLQAALKGHDSVVSILIK-NKANL 1072
                  69********************.78886 PP

  == domain 6  score: 13.1 bits;  conditional E-value: 5.7e-05
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                   +tpL  Aa+ g+ ++v +L++ + a++ 
  EEA19687.1 1080 DQTPLLNAAEKGHDNVVSLLIK-NQANIE 1107
                  69********************.899985 PP

  == domain 7  score: 15.5 bits;  conditional E-value: 9.4e-06
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                  G+tpL  A+++g+ +iv +L++ + a++ 
  EEA19687.1 1114 GQTPLLKAIENGHDNIVSLLIK-NKANIE 1141
                  89********************.799885 PP

  == domain 8  score: 14.0 bits;  conditional E-value: 2.8e-05
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                   +tpL +Aa+ g+ +iv +Ll+ + a++ 
  EEA19687.1 1148 DQTPLLQAAEKGHDNIVSLLLK-NKANIE 1175
                  69********************.799885 PP

  == domain 9  score: 18.4 bits;  conditional E-value: 1.1e-06
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                  G+tpL +Aa++g+++ v++L++ +ga++ 
  EEA19687.1 1181 GQTPLGQAAENGHYSTVELLVR-NGANIE 1208
                  9*************99******.8**996 PP

  == domain 10  score: 10.7 bits;  conditional E-value: 0.00034
       Ank_3    3 etpLhlAarsgnleivkfLlenkgadv 29  
                  +tpL +A + g++++v+fL++ +ga++
  EEA19687.1 1216 QTPLCQATEKGHYSVVEFLVR-NGANI 1241
                  89*******************.8**98 PP

  == domain 11  score: 13.9 bits;  conditional E-value: 3.2e-05
       Ank_3    1 nGetpLhlAarsgnleivkfLlenkgadvn 30  
                  +G+tpL +Aa+ g++++v+fL + +ga + 
  EEA19687.1 1248 YGQTPLCQAAEKGHYSVVEFLTR-NGAKIE 1276
                  79*********************.899885 PP

  == domain 12  score: 14.9 bits;  conditional E-value: 1.5e-05
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                  G+tpL  Aa+++++++v+fL++ +ga + 
  EEA19687.1 1283 GQTPLCKAAENDHYSVVEFLVR-NGASIE 1310
                  9*********************.8*9985 PP

  == domain 13  score: 15.0 bits;  conditional E-value: 1.4e-05
       Ank_3    1 nGetpLhlAarsgnleivkfLlenkgadvn 30  
                  +G+tpL +Aa+ g++++v+fL + +ga++ 
  EEA19687.1 1316 YGQTPLCQAAKKGHYSVVEFLTR-NGANIE 1344
                  79*********************.8**996 PP

  == domain 14  score: 18.9 bits;  conditional E-value: 7.3e-07
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                  G+tpL +Aa++g++++v+fL++ +ga++ 
  EEA19687.1 1351 GQTPLCQAAENGHFSVVEFLVR-NGANIE 1378
                  9*********************.8**996 PP

  == domain 15  score: 19.7 bits;  conditional E-value: 3.8e-07
       Ank_3    1 nGetpLhlAarsgnleivkfLlenkgadvn 30  
                  +G+tpL +Aa++g++++v+fL++ +ga++ 
  EEA19687.1 1384 YGQTPLCQAAENGHFSVVEFLVR-NGANIE 1412
                  79*********************.8**996 PP

  == domain 16  score: 18.9 bits;  conditional E-value: 7e-07
       Ank_3    1 nGetpLhlAarsgnleivkfLlenkg 26  
                  +G+tpL++Aa  g+++iv+fL++ +g
  EEA19687.1 1418 YGQTPLYQAANKGHYSIVEFLIR-NG 1442
                  79*********************.55 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0         9   1.8e+04       7      25 ..     914     932 ..     911     939 .. 0.82
   2 !   25.5   0.2   7.2e-09   1.4e-05       2      54 ..     947     997 ..     946     998 .. 0.88
   3 !   22.0   0.0   8.9e-08   0.00018       3      54 ..    1014    1065 ..    1011    1067 .. 0.86
   4 !   25.2   0.0   8.7e-09   1.7e-05       3      55 .]    1082    1134 ..    1081    1134 .. 0.96
   5 !   32.9   0.0   3.5e-11   6.9e-08       3      55 .]    1150    1201 ..    1149    1201 .. 0.96
   6 !   27.9   0.0   1.3e-09   2.6e-06       3      54 ..    1217    1268 ..    1204    1269 .. 0.95
   7 !   14.0   0.0     3e-05     0.059      24      55 .]    1272    1303 ..    1270    1303 .. 0.90
   8 !   35.5   0.0   5.4e-12   1.1e-08       3      54 ..    1285    1336 ..    1283    1337 .. 0.97
   9 !   18.2   0.0   1.4e-06    0.0028      23      55 .]    1339    1371 ..    1338    1371 .. 0.94
  10 !   38.6   0.0   5.4e-13   1.1e-09       3      55 .]    1353    1405 ..    1351    1405 .. 0.97
  11 !   38.2   0.0   7.3e-13   1.4e-09       3      55 .]    1387    1439 ..    1387    1439 .. 0.98

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 9
       Ank_4   7 yaaisgrlelvrlLlekga 25 
                 +a+++ +++l+ + l++g+
  EEA19687.1 914 WAVKERHEPLLSIALDSGK 932
                 7889999999999999886 PP

  == domain 2  score: 25.5 bits;  conditional E-value: 7.2e-09
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgad.inaqdnrsGetalhiAakrgnveilklL 54 
                 l++Lh a + g +++v++Ll  g+  +n   + ++ talh+A +rg+++i+ l 
  EEA19687.1 947 LPPLHLASKLGYYDIVKSLL--GIChVNSL-DVEDCTALHHASSRGHIDIVSLI 997
                 789****************9..43338887.999*****************885 PP

  == domain 3  score: 22.0 bits;  conditional E-value: 8.9e-08
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54  
                  t+L  a + g+  +v +L+e++adi  +dn  ++t+l  Aa++g+ +++  L
  EEA19687.1 1014 TPLWFASANGHDNVVSILIENKADIETTDNQHDQTPLLQAALKGHDSVVSIL 1065
                  89**************************555577**********95555555 PP

  == domain 4  score: 25.2 bits;  conditional E-value: 8.7e-09
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  t+L +aa++g+  +v lL+ + a+i a+d   G+t+l +A+ +g+ +i+ lL+
  EEA19687.1 1082 TPLLNAAEKGHDNVVSLLIKNQANIEATDTLIGQTPLLKAIENGHDNIVSLLI 1134
                  7999************************9999*************99999987 PP

  == domain 5  score: 32.9 bits;  conditional E-value: 3.5e-11
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  t+L +aa++g+  +v lLl ++a+i a+ n +G+t+l  Aa +g+++ ++lL+
  EEA19687.1 1150 TPLLQAAEKGHDNIVSLLLKNKANIEAC-NPRGQTPLGQAAENGHYSTVELLV 1201
                  7999************************.888*******************96 PP

  == domain 6  score: 27.9 bits;  conditional E-value: 1.3e-09
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54  
                  t+L +a ++g++ +v++L+ +ga+i ++d  +G+t+l  Aa +g+++++++L
  EEA19687.1 1217 TPLCQATEKGHYSVVEFLVRNGANIEERDIQYGQTPLCQAAEKGHYSVVEFL 1268
                  78999999********************6667*******************9 PP

  == domain 7  score: 14.0 bits;  conditional E-value: 3e-05
       Ank_4   24 gadinaqdnrsGetalhiAakrgnveilklLl 55  
                  ga i a+d r+G+t+l +Aa + +++++++L+
  EEA19687.1 1272 GAKIEARDIRRGQTPLCKAAENDHYSVVEFLV 1303
                  66778898899*******************96 PP

  == domain 8  score: 35.5 bits;  conditional E-value: 5.4e-12
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54  
                  t+L +aa+  ++ +v++L+ +ga+i a+d+ +G+t+l  Aak+g+++++++L
  EEA19687.1 1285 TPLCKAAENDHYSVVEFLVRNGASIEARDDLYGQTPLCQAAKKGHYSVVEFL 1336
                  89*************************************************9 PP

  == domain 9  score: 18.2 bits;  conditional E-value: 1.4e-06
       Ank_4   23 kgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  +ga+i a d r+G+t+l  Aa +g+++++++L+
  EEA19687.1 1339 NGANIEAIDTRRGQTPLCQAAENGHFSVVEFLV 1371
                  6899999999*********************96 PP

  == domain 10  score: 38.6 bits;  conditional E-value: 5.4e-13
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  t+L +aa+ g++ +v++L+ +ga+i a+d+ +G+t+l  Aa +g+++++++L+
  EEA19687.1 1353 TPLCQAAENGHFSVVEFLVRNGANIEARDDLYGQTPLCQAAENGHFSVVEFLV 1405
                  89*************************************************96 PP

  == domain 11  score: 38.2 bits;  conditional E-value: 7.3e-13
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  t+L +aa+ g++ +v++L+ +ga+i a+d+ +G+t+l+ Aa +g+++i+++L+
  EEA19687.1 1387 TPLCQAAENGHFSVVEFLVRNGANIEARDDLYGQTPLYQAANKGHYSIVEFLI 1439
                  79**************************************************8 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.8   0.1   6.2e-05      0.12       5      31 ..     949     975 ..     949     976 .. 0.89
   2 !   15.5   0.0   8.9e-06     0.018       3      25 ..     979    1003 ..     977    1009 .. 0.87
   3 !   15.7   0.0   7.9e-06     0.016       2      32 .]    1012    1043 ..    1011    1043 .. 0.92
   4 !   11.5   0.2   0.00016      0.32       3      32 .]    1047    1077 ..    1045    1077 .. 0.92
   5 !   11.4   0.1   0.00017      0.34       3      31 ..    1081    1110 ..    1079    1111 .. 0.90
   6 !   18.5   0.1   9.7e-07    0.0019       2      32 .]    1114    1145 ..    1113    1145 .. 0.94
   7 !   12.5   0.1   8.1e-05      0.16       3      31 ..    1149    1178 ..    1147    1179 .. 0.90
   8 !   14.3   0.0   2.1e-05     0.043       2      31 ..    1181    1211 ..    1180    1211 .. 0.94
   9 !    8.3   0.0    0.0017       3.4       3      31 ..    1216    1245 ..    1214    1246 .. 0.88
  10 !   11.5   0.0   0.00017      0.33       1      31 [.    1248    1279 ..    1248    1280 .. 0.91
  11 !   16.4   0.0   4.7e-06    0.0095       2      32 .]    1283    1314 ..    1282    1314 .. 0.95
  12 !   13.4   0.0   4.1e-05     0.083       1      31 [.    1316    1347 ..    1316    1348 .. 0.90
  13 !   19.0   0.0   6.9e-07    0.0014       2      32 .]    1351    1382 ..    1350    1382 .. 0.95
  14 !   19.8   0.0   3.9e-07   0.00078       1      32 []    1384    1416 ..    1384    1416 .. 0.95
  15 !   12.9   0.0   5.8e-05      0.11       1      24 [.    1418    1442 ..    1418    1447 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 6.2e-05
                 HHHHHHHHTTHHHHHHHHTT.TSTTCBT CS
         Ank   5 PLHlAatngkkriiklLLhG.Anlnald 31 
                 PLHlA+  g  +i+k LL G + +n+ld
  EEA19687.1 949 PLHLASKLGYYDIVKSLL-GiCHVNSLD 975
                 9*****999999******.976799988 PP

  == domain 2  score: 15.5 bits;  conditional E-value: 8.9e-06
                  BBHHHHHHHHTTHHHHHHHH..TTT CS
         Ank    3 nTPLHlAatngkkriiklLL..hGA 25  
                  +T+LH A+++g+ +i++l+L  +GA
  EEA19687.1  979 CTALHHASSRGHIDIVSLILktKGA 1003
                  8****************99985587 PP

  == domain 3  score: 15.7 bits;  conditional E-value: 7.9e-06
                  SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAnlnaldn 32  
                  G TPL  A+ ng+ ++++ L+ + A++  +dn
  EEA19687.1 1012 GVTPLWFASANGHDNVVSILIeNKADIETTDN 1043
                  99*******************778**998886 PP

  == domain 4  score: 11.5 bits;  conditional E-value: 0.00016
                  BBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank    3 nTPLHlAatngkkriiklLL.hGAnlnaldn 32  
                   TPL  Aa  g+ ++++ L+ + Anl a++n
  EEA19687.1 1047 QTPLLQAALKGHDSVVSILIkNKANLEARNN 1077
                  69******9***********667******97 PP

  == domain 5  score: 11.4 bits;  conditional E-value: 0.00017
                  BBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    3 nTPLHlAatngkkriiklLL.hGAnlnald 31  
                   TPL  Aa  g+ ++++lL+ + An+ a+d
  EEA19687.1 1081 QTPLLNAAEKGHDNVVSLLIkNQANIEATD 1110
                  6999999*99**********667****998 PP

  == domain 6  score: 18.5 bits;  conditional E-value: 9.7e-07
                  SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAnlnaldn 32  
                  G TPL  A+ ng+ +i++lL+ + An+ a+dn
  EEA19687.1 1114 GQTPLLKAIENGHDNIVSLLIkNKANIEARDN 1145
                  99*******************667*******8 PP

  == domain 7  score: 12.5 bits;  conditional E-value: 8.1e-05
                  BBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    3 nTPLHlAatngkkriiklLL.hGAnlnald 31  
                   TPL  Aa  g+ +i++lLL + An+ a +
  EEA19687.1 1149 QTPLLQAAEKGHDNIVSLLLkNKANIEACN 1178
                  6*******************667**99876 PP

  == domain 8  score: 14.3 bits;  conditional E-value: 2.1e-05
                  SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAnlnald 31  
                  G TPL  Aa ng+ + ++lL+ +GAn+ a++
  EEA19687.1 1181 GQTPLGQAAENGHYSTVELLVrNGANIEAKT 1211
                  99*******************99****9986 PP

  == domain 9  score: 8.3 bits;  conditional E-value: 0.0017
                  BBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    3 nTPLHlAatngkkriiklLL.hGAnlnald 31  
                   TPL  A   g+ +++++L+ +GAn+  +d
  EEA19687.1 1216 QTPLCQATEKGHYSVVEFLVrNGANIEERD 1245
                  599999999999********99***98776 PP

  == domain 10  score: 11.5 bits;  conditional E-value: 0.00017
                  TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    1 dGnTPLHlAatngkkriiklLL.hGAnlnald 31  
                  +G TPL  Aa  g+ +++++L  +GA + a+d
  EEA19687.1 1248 YGQTPLCQAAEKGHYSVVEFLTrNGAKIEARD 1279
                  69********99*******77788****9999 PP

  == domain 11  score: 16.4 bits;  conditional E-value: 4.7e-06
                  SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAnlnaldn 32  
                  G TPL  Aa n++ +++++L+ +GA++ a+d+
  EEA19687.1 1283 GQTPLCKAAENDHYSVVEFLVrNGASIEARDD 1314
                  99*******************99******996 PP

  == domain 12  score: 13.4 bits;  conditional E-value: 4.1e-05
                  TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    1 dGnTPLHlAatngkkriiklLL.hGAnlnald 31  
                  +G TPL  Aa  g+ +++++L  +GAn+ a d
  EEA19687.1 1316 YGQTPLCQAAKKGHYSVVEFLTrNGANIEAID 1347
                  69*****************77788****8876 PP

  == domain 13  score: 19.0 bits;  conditional E-value: 6.9e-07
                  SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAnlnaldn 32  
                  G TPL  Aa ng+ +++++L+ +GAn+ a+d+
  EEA19687.1 1351 GQTPLCQAAENGHFSVVEFLVrNGANIEARDD 1382
                  99*******************99*******96 PP

  == domain 14  score: 19.8 bits;  conditional E-value: 3.9e-07
                  TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank    1 dGnTPLHlAatngkkriiklLL.hGAnlnaldn 32  
                  +G TPL  Aa ng+ +++++L+ +GAn+ a+d+
  EEA19687.1 1384 YGQTPLCQAAENGHFSVVEFLVrNGANIEARDD 1416
                  69********************99*******96 PP

  == domain 15  score: 12.9 bits;  conditional E-value: 5.8e-05
                  TSBBHHHHHHHHTTHHHHHHHH.TT CS
         Ank    1 dGnTPLHlAatngkkriiklLL.hG 24  
                  +G TPL  Aa+ g+ +i+++L+ +G
  EEA19687.1 1418 YGQTPLYQAANKGHYSIVEFLIrNG 1442
                  69********************777 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.3   0.0     0.003         6      19      36 ..     949     966 ..     944     970 .. 0.92
   2 !   10.9   0.0   0.00022      0.44       9      36 ..     971     998 ..     968    1006 .. 0.81
   3 !   14.0   0.0   2.4e-05     0.048      14      53 ..    1010    1050 ..    1000    1050 .. 0.92
   4 !   10.0   0.0   0.00044      0.87      13      46 ..    1043    1076 ..    1041    1077 .. 0.90
   5 !   11.5   0.1   0.00015       0.3      12      46 ..    1076    1110 ..    1072    1112 .. 0.90
   6 !    9.7   0.0   0.00053       1.1      15      47 ..    1113    1145 ..    1110    1146 .. 0.93
   7 !   20.6   0.0     2e-07   0.00039      13      53 ..    1145    1185 ..    1143    1186 .. 0.94
   8 !   11.2   0.0   0.00019      0.37      13      47 ..    1178    1212 ..    1178    1217 .. 0.90
   9 !   14.2   0.0   2.1e-05     0.043      12      47 ..    1211    1246 ..    1200    1248 .. 0.82
  10 !   14.7   0.0   1.4e-05     0.028      15      46 ..    1248    1279 ..    1246    1282 .. 0.87
  11 !   17.1   0.0   2.6e-06    0.0051      15      46 ..    1282    1313 ..    1277    1315 .. 0.91
  12 !   19.7   0.0   3.9e-07   0.00078      12      46 ..    1313    1347 ..    1312    1350 .. 0.88
  13 !   22.7   0.0   4.3e-08   8.6e-05      12      46 ..    1348    1381 ..    1339    1382 .. 0.85
  14 !   24.3   0.0   1.5e-08   2.9e-05      12      47 ..    1381    1416 ..    1377    1418 .. 0.93
  15 !   18.6   0.0   8.5e-07    0.0017      12      39 ..    1415    1442 ..    1413    1451 .. 0.87

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.003
       Ank_5  19 pLhvAakygaadvvrlLl 36 
                 pLh+A+k g+ d+v+ Ll
  EEA19687.1 949 PLHLASKLGYYDIVKSLL 966
                 9***************99 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00022
       Ank_5   9 vnrldgggntpLhvAakygaadvvrlLl 36 
                 vn ld +  t+Lh+A+++g+ d+v l+l
  EEA19687.1 971 VNSLDVEDCTALHHASSRGHIDIVSLIL 998
                 566666666***************8888 PP

  == domain 3  score: 14.0 bits;  conditional E-value: 2.4e-05
       Ank_5   14 gggntpLhvAakygaadvvrlLlargadlnltdsrG.ltal 53  
                  + g+tpL +A+ +g+ +vv +L+++ ad+ +td++  +t+l
  EEA19687.1 1010 KSGVTPLWFASANGHDNVVSILIENKADIETTDNQHdQTPL 1050
                  6799******************************9888886 PP

  == domain 4  score: 10.0 bits;  conditional E-value: 0.00044
       Ank_5   13 dgggntpLhvAakygaadvvrlLlargadlnltd 46  
                  +++ +tpL +Aa +g+ +vv +L+++ a+l +++
  EEA19687.1 1043 NQHDQTPLLQAALKGHDSVVSILIKNKANLEARN 1076
                  67788*********************99999888 PP

  == domain 5  score: 11.5 bits;  conditional E-value: 0.00015
       Ank_5   12 ldgggntpLhvAakygaadvvrlLlargadlnltd 46  
                  ++++ +tpL +Aa++g+ +vv lL++++a++ +td
  EEA19687.1 1076 NNPHDQTPLLNAAEKGHDNVVSLLIKNQANIEATD 1110
                  577778************************99998 PP

  == domain 6  score: 9.7 bits;  conditional E-value: 0.00053
       Ank_5   15 ggntpLhvAakygaadvvrlLlargadlnltds 47  
                   g+tpL  A+++g+ ++v lL+++ a++ ++d+
  EEA19687.1 1113 IGQTPLLKAIENGHDNIVSLLIKNKANIEARDN 1145
                  589************************999986 PP

  == domain 7  score: 20.6 bits;  conditional E-value: 2e-07
       Ank_5   13 dgggntpLhvAakygaadvvrlLlargadlnltdsrGltal 53  
                  + + +tpL +Aa++g+ ++v lLl++ a++ +++ rG+t+l
  EEA19687.1 1145 NLHDQTPLLQAAEKGHDNIVSLLLKNKANIEACNPRGQTPL 1185
                  56778***********************************8 PP

  == domain 8  score: 11.2 bits;  conditional E-value: 0.00019
       Ank_5   13 dgggntpLhvAakygaadvvrlLlargadlnltds 47  
                  +++g+tpL +Aa++g+ + v+lL+ +ga++ ++++
  EEA19687.1 1178 NPRGQTPLGQAAENGHYSTVELLVRNGANIEAKTG 1212
                  67899************************999886 PP

  == domain 9  score: 14.2 bits;  conditional E-value: 2.1e-05
       Ank_5   12 ldgggntpLhvAakygaadvvrlLlargadlnltds 47  
                  +  +++tpL++A ++g+ +vv++L+ +ga++  +d 
  EEA19687.1 1211 TGLYSQTPLCQATEKGHYSVVEFLVRNGANIEERDI 1246
                  556888***********************9988875 PP

  == domain 10  score: 14.7 bits;  conditional E-value: 1.4e-05
       Ank_5   15 ggntpLhvAakygaadvvrlLlargadlnltd 46  
                  +g+tpL++Aa++g+ +vv++L  +ga + ++d
  EEA19687.1 1248 YGQTPLCQAAEKGHYSVVEFLTRNGAKIEARD 1279
                  899******************98888777776 PP

  == domain 11  score: 17.1 bits;  conditional E-value: 2.6e-06
       Ank_5   15 ggntpLhvAakygaadvvrlLlargadlnltd 46  
                  +g+tpL+ Aa++ + +vv++L+ +ga++ ++d
  EEA19687.1 1282 RGQTPLCKAAENDHYSVVEFLVRNGASIEARD 1313
                  688************************99998 PP

  == domain 12  score: 19.7 bits;  conditional E-value: 3.9e-07
       Ank_5   12 ldgggntpLhvAakygaadvvrlLlargadlnltd 46  
                   d +g+tpL++Aak+g+ +vv++L  +ga++ + d
  EEA19687.1 1313 DDLYGQTPLCQAAKKGHYSVVEFLTRNGANIEAID 1347
                  5899********************99999886655 PP

  == domain 13  score: 22.7 bits;  conditional E-value: 4.3e-08
       Ank_5   12 ldgggntpLhvAakygaadvvrlLlargadlnltd 46  
                  + ++g+tpL++Aa++g+++vv++L+ +ga++ ++d
  EEA19687.1 1348 T-RRGQTPLCQAAENGHFSVVEFLVRNGANIEARD 1381
                  3.4677************************99998 PP

  == domain 14  score: 24.3 bits;  conditional E-value: 1.5e-08
       Ank_5   12 ldgggntpLhvAakygaadvvrlLlargadlnltds 47  
                   d +g+tpL++Aa++g+++vv++L+ +ga++ ++d+
  EEA19687.1 1381 DDLYGQTPLCQAAENGHFSVVEFLVRNGANIEARDD 1416
                  6899***************************99985 PP

  == domain 15  score: 18.6 bits;  conditional E-value: 8.5e-07
       Ank_5   12 ldgggntpLhvAakygaadvvrlLlarg 39  
                   d +g+tpL +Aa++g+ ++v++L+ +g
  EEA19687.1 1415 DDLYGQTPLYQAANKGHYSIVEFLIRNG 1442
                  6899*********************444 PP

>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.8   0.0   3.6e-14   7.1e-11       2     233 ..      22     316 ..      21     324 .. 0.79

  Alignments for each domain:
  == domain 1  score: 41.8 bits;  conditional E-value: 3.6e-14
                 EEEEESSHHHHHHHHHH...EEEEEEEEEE.TTEEEEEEEETTEEEEEEE--...SSHHHHHHHHHHHHHHHC--SEE.EEEEEEEES...STTT-TT- CS
   PNP_UDP_1   2 iaiivgspgevellaes...pleetpfgregrgfkfvtGtlkgkpvvivstG...iGkpnaavvaeirllkefgvkai.iriGtaGgl...npdlkvGD 90 
                 ia i + p e++   +     + +++  ++    ++++G+++ ++++i++      G+++aa + +  +   f + ++ +++G+ Gg+   ++d+++GD
  EEA19687.1  22 IAWISALPTEMAVAEAMldeRYPDLQTPPN-DDNTYIFGRMHSHNIIIACLPagvYGTTSAA-TVASQIRTTFPSLRFgLMVGIGGGVaseDADIRLGD 118
                 667778887777666665554555555555.779****************999977******.4444444456555554999******999999***** PP

                 EEEEEE......EEESSSCCGCCTHHCC............................................TCCCCTTSSEE--HHHHHHHHH..... CS
   PNP_UDP_1  91 vvipdd......ainfdgrsplygpkee............................................gqyfpdsydapadpelrallke..... 134
                 vv+++       +i++d++ +                                                   + y++++ ++++ ++  ++l+      
  EEA19687.1 119 VVVSKPtgtfggVIQYDYGKA------LhdgcferigmlnkpplvlltavstlqaahmlrpsripelisemvMKYPIMKDKFTYPSDAQDMLFDpksdh 211
                 ******555555566666666......2334466999***********************************999999999999999999999966655 PP

                 ....CHHTTT...................TTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTBETTCTCH CS
   PNP_UDP_1 135 ....aaealg...................ikvhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArelgipfaairvvsdlaaggadaeat 210
                     +                        + +h+G++a+++++  + + +++l ++lg+ + eME+a +       + p+++ir++ d+a+        
  EEA19687.1 212 adsgN----TcancdtsrqvkrvtrhshdPAIHYGLIASGNQVMKDGQLRDSLAQKLGVLCFEMEAAGLME-----NFPCLVIRGICDYADS------- 294
                 55541....04555666777777788889******************99999*************987643.....8***********7777....... PP

                 .HCCCHHHHHHHHHHHHHHHHHH CS
   PNP_UDP_1 211 heeveefaqeaaknaaalllall 233
                    +++ ++ aa +aaa +++ll
  EEA19687.1 295 -HKNKQWQPYAAATAAAYAKELL 316
                 .5666666666666666666665 PP

>> DUF1191  Protein of unknown function (DUF1191)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0     0.035        69     166     181 ..    1216    1231 ..    1199    1232 .. 0.82
   2 ?    1.3   0.0      0.13   2.6e+02     167     181 ..    1251    1265 ..    1236    1266 .. 0.84
   3 ?   -2.8   0.0       2.2   4.5e+03     167     181 ..    1285    1299 ..    1270    1301 .. 0.79
   4 ?    1.6   0.0       0.1     2e+02     167     181 ..    1319    1333 ..    1300    1335 .. 0.84
   5 ?    2.3   0.0     0.062   1.2e+02     167     181 ..    1353    1367 ..    1335    1368 .. 0.77
   6 ?    1.7   0.0     0.096   1.9e+02     167     181 ..    1387    1401 ..    1372    1402 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.035
     DUF1191  166 ssnvCavssqGhfalv 181 
                  ++  C+++++Gh+++v
  EEA19687.1 1216 QTPLCQATEKGHYSVV 1231
                  5678***********9 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.13
     DUF1191  167 snvCavssqGhfalv 181 
                  +  C++ ++Gh+++v
  EEA19687.1 1251 TPLCQAAEKGHYSVV 1265
                  568***********9 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 2.2
     DUF1191  167 snvCavssqGhfalv 181 
                  +  C++ ++ h+++v
  EEA19687.1 1285 TPLCKAAENDHYSVV 1299
                  568***********9 PP

  == domain 4  score: 1.6 bits;  conditional E-value: 0.1
     DUF1191  167 snvCavssqGhfalv 181 
                  +  C++ ++Gh+++v
  EEA19687.1 1319 TPLCQAAKKGHYSVV 1333
                  568***********9 PP

  == domain 5  score: 2.3 bits;  conditional E-value: 0.062
     DUF1191  167 snvCavssqGhfalv 181 
                  +  C++ ++Ghf++v
  EEA19687.1 1353 TPLCQAAENGHFSVV 1367
                  678***********9 PP

  == domain 6  score: 1.7 bits;  conditional E-value: 0.096
     DUF1191  167 snvCavssqGhfalv 181 
                  +  C++ ++Ghf++v
  EEA19687.1 1387 TPLCQAAENGHFSVV 1401
                  568***********9 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   3.4e-06    0.0068       2     129 ..     410     569 ..     409     585 .. 0.77

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 3.4e-06
                 CEEEEC-TTTCHHHH........HHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-.......-HCHHHCCCCTS--SSS-C................. CS
       NACHT   2 lvilqGeaGsGKTtL........lqklalawaegklpqgafklvFflslrelsrsgna....rsladllfsqlpepaapvse................. 71 
                 +++  G+ GsGKT+         l  +++a++ ++ +      vFf ++ e  +s +a     s++++l++ +   +   +e                 
  EEA19687.1 410 YLWCSGKIGSGKTMIalvalgfpLTAVVDAAKYRNSELP-TATVFFYCQNEQDESLQApailSSFIKQLCEFMRRTSNSFPEgalqelqkffgndrivp 507
                 68999*********8333333334677777777776665.59999999999999888855555555555555555555555598889999999999999 PP

                 .......CHHHHCCSCCCEEEEEE-STT-SS-TCH.........HHHHH.CTTTTT--EEEEEEEC CS
       NACHT  72 .......vwavllelperlLlilDglDelvtdlgqkekqpvrtlLseli.rkkllpeasllltvrp 129
                         + ++  +   +  ++Dg+D l + +++    ++ +l+++++  +k+l ++++ll +r 
  EEA19687.1 508 dfedlkdLFMHIFYQVPNTIYVVDGIDMLDRNNSK----RLLKLIQSIFcGRKSLEGSRILLLSRD 569
                 99999998888888888888***********8877....999999887536889999999998886 PP

>> PEGA  PEGA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.1       3.3   6.6e+03      43      62 ..     669     688 ..     668     690 .. 0.87
   2 ?   -0.7   0.0      0.67   1.3e+03      21      35 ..    1112    1126 ..    1102    1130 .. 0.81
   3 ?   -2.8   0.1       3.1   6.1e+03      23      37 ..    1181    1195 ..    1178    1197 .. 0.88
   4 ?   -1.7   0.0       1.4   2.8e+03      21      38 ..    1213    1230 ..    1202    1231 .. 0.74
   5 ?    2.7   0.0     0.059   1.2e+02      13      38 ..    1239    1264 ..    1235    1265 .. 0.80
   6 ?   -3.2   0.0         4   7.9e+03      12      38 ..    1272    1298 ..    1270    1299 .. 0.75
   7 ?    3.7   0.0     0.028        56      11      38 ..    1305    1332 ..    1303    1333 .. 0.89
   8 ?   -2.7   0.0         3   5.9e+03      19      38 ..    1347    1366 ..    1338    1367 .. 0.72
   9 ?    0.5   0.0       0.3   5.9e+02      11      38 ..    1373    1400 ..    1371    1401 .. 0.85
  10 ?    2.4   0.0     0.075   1.5e+02      11      38 ..    1407    1434 ..    1405    1435 .. 0.88

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 3.3
        PEGA  43 eGYedlektvtvtagetvkl 62 
                 e Y+   +++++++++tvk+
  EEA19687.1 669 ETYQYCIQRINLQDNRTVKV 688
                 67888999*********998 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.67
        PEGA   21 ylGkTPvtlsleaGn 35  
                   +G+TP+  ++e+G 
  EEA19687.1 1112 LIGQTPLLKAIENGH 1126
                  68**********997 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 3.1
        PEGA   23 GkTPvtlsleaGnys 37  
                  G+TP+  + e+G ys
  EEA19687.1 1181 GQTPLGQAAENGHYS 1195
                  9*******99*9997 PP

  == domain 4  score: -1.7 bits;  conditional E-value: 1.4
        PEGA   21 ylGkTPvtlsleaGnysl 38  
                   + +TP+  + e+G ys+
  EEA19687.1 1213 LYSQTPLCQATEKGHYSV 1230
                  4559************98 PP

  == domain 5  score: 2.7 bits;  conditional E-value: 0.059
        PEGA   13 atVyidGkylGkTPvtlsleaGnysl 38  
                  a++     ++G+TP+  + e+G ys+
  EEA19687.1 1239 ANIEERDIQYGQTPLCQAAEKGHYSV 1264
                  5555555689**************98 PP

  == domain 6  score: -3.2 bits;  conditional E-value: 4
        PEGA   12 GatVyidGkylGkTPvtlsleaGnysl 38  
                  Ga++       G+TP+  + e+  ys+
  EEA19687.1 1272 GAKIEARDIRRGQTPLCKAAENDHYSV 1298
                  556655566679****99999988887 PP

  == domain 7  score: 3.7 bits;  conditional E-value: 0.028
        PEGA   11 eGatVyidGkylGkTPvtlsleaGnysl 38  
                  +Ga++      +G+TP+  + ++G ys+
  EEA19687.1 1305 NGASIEARDDLYGQTPLCQAAKKGHYSV 1332
                  78999998999***************98 PP

  == domain 8  score: -2.7 bits;  conditional E-value: 3
        PEGA   19 GkylGkTPvtlsleaGnysl 38  
                      G+TP+  + e+G  s+
  EEA19687.1 1347 DTRRGQTPLCQAAENGHFSV 1366
                  4577*****99999998887 PP

  == domain 9  score: 0.5 bits;  conditional E-value: 0.3
        PEGA   11 eGatVyidGkylGkTPvtlsleaGnysl 38  
                  +Ga++      +G+TP+  + e+G  s+
  EEA19687.1 1373 NGANIEARDDLYGQTPLCQAAENGHFSV 1400
                  78888888889******99999998887 PP

  == domain 10  score: 2.4 bits;  conditional E-value: 0.075
        PEGA   11 eGatVyidGkylGkTPvtlsleaGnysl 38  
                  +Ga++      +G+TP+  +  +G ys+
  EEA19687.1 1407 NGANIEARDDLYGQTPLYQAANKGHYSI 1434
                  78888888889***************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1452 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       389  (0.0216967); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.93u 0.36s 00:00:01.29 Elapsed: 00:00:00.52
# Mc/sec: 8435.47
//
Query:       EEA19688.1  [L=255]
Description: rhamnogalacturonan acetylesterase RgaE [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.9e-12   48.0   0.7    2.3e-12   47.7   0.7    1.1  1  Lipase_GDSL_2  GDSL-like Lipase/Acylhydrolase family
    7.5e-06   26.1   0.0    9.4e-06   25.7   0.0    1.1  1  Lipase_GDSL    GDSL-like Lipase/Acylhydrolase
  ------ inclusion threshold ------
      0.056   13.8   0.0        5.3    7.4   0.0    2.5  2  DUF1330        Domain of unknown function (DUF1330)
      0.094   12.8   0.0        1.3    9.1   0.0    2.4  2  NLPC_P60       NlpC/P60 family


Domain annotation for each model (and alignments):
>> Lipase_GDSL_2  GDSL-like Lipase/Acylhydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.7   0.7   5.1e-16   2.3e-12       2     178 ..      27     224 ..      26     225 .. 0.81

  Alignments for each domain:
  == domain 1  score: 47.7 bits;  conditional E-value: 5.1e-16
                    EESHHHH.TCTTBCCHCHHCCCCCCCHHHTT-EEEEE.EEHCCH-H..HHHHHHHH.CTGGG-T.SEEEEE--CCCCCTT--HHHHHHH....... CS
  Lipase_GDSL_2   2 lGDSiTa.GygadgggrsypaylarllaarlgldvvnnlgvsGattallrllerlr.dllrlkp.dlvtiliGtNDlgrgvpaaaaaand...... 88 
                     GDS +a G    ggg + +++ ++++a+ l l+v n  ++ G++  +++ +++++  +++++p d v+i +G+ND g  +p +  ++++      
     EEA19688.1  27 AGDSTMArG----GGGSGTDGW-GQYIASYLSLNVSN-QAIAGRSARSYAREGHFNtIASEIQPgDFVVIEFGHNDGGSIAPIDNGRTDCpgngte 116
                    5******55....788999999.99999999999999.******66559999999999999999************65555555555555666688 PP

                    ...................HHHHHHHHCCC...GEEECEEEEE-TTT-TTSTCCHHHHHHHHHHHHHHHHHHCT-EEE-H....HHHHHHCCCCCG CS
  Lipase_GDSL_2  89 ..................nleelidalraaapgarilvlgplpptpeaaadarelnaviaaynealrevaaeegvpfvDl....hdaladsgerla 162
                                       le+  ++ +a+  ga ++ +   p++p + +  +++  +   y+e ++ev    gv +vD     ++++ d g + +
     EEA19688.1 117 tcsttyngvaetvltfpaYLEKAANTFKAK--GAHVIIASQTPNNPWETGTFAYSPNRFWGYAEPAAEV---SGVKYVDHggyvASIFKDLGVTTV 207
                    888889999999997777777777777777..9999989999999999999999777778887777777...589999998888888888887777 PP

                    GBBTTS..SSB-HHHHH CS
  Lipase_GDSL_2 163 dlladdg.lHPnaaGyr 178
                    d +++++  H + aG +
     EEA19688.1 208 DSYYPNDhTHTSVAGAK 224
                    76666666999999976 PP

>> Lipase_GDSL  GDSL-like Lipase/Acylhydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.7   0.0   2.1e-09   9.4e-06       1     200 []      24     230 ..      24     230 .. 0.75

  Alignments for each domain:
  == domain 1  score: 25.7 bits;  conditional E-value: 2.1e-09
                  EEEEESHHHH...TTTHHHHHHHCCCCEECCCTTC.GCEEEEEEECTTHHHHHHHCCHECTTTECHHHHHCTTS.EEEEE--CTCC............ CS
                  xxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxx............ RF
  Lipase_GDSL   1 ivafGDSltd...Gdgaatlntiqlktpknlnefdlaldrianignkgasdnelqqllnkyplkseqlkalhpd.lviislGtNDs............ 82 
                  i++ GDS ++   G +++ ++   + ++ +ln          n+++ g s +  ++       +   + + +p   v+i++G+ND             
   EEA19688.1  24 IYLAGDSTMArggGGSGTDGWGQYIASYLSLNVS--------NQAIAGRSARSYAREG----HFNTIASEIQPGdFVVIEFGHNDGgsiapidngrtd 109
                  7789*******99778888888888888888764........3333333333333333....2233445666666*********************** PP

                  ......-EECSSCTTTCEEHHHHHHHHHHHHHHHHHHHHTTEEEEEEE-SSTCHCTCCCCHCCHH.HHHHHHHHHHHHHHHHHHHCTEEEECHHHHHH CS
                  ......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Lipase_GDSL  83 ......nlgkkstdaakkeaeeyiknlreaikelkeegapkaivvlvsppglgpqeekdakklge.kgnefvgeynqrlndlaekdgfavvDlydelq 173
                        + ++ +++ + +++  + + l++a +  k   a++a+v++ s+ + +p    +++++    +n+f g+       +ae +g+++vD+     
   EEA19688.1 110 cpgngtETCSTTYNGVAETVLTFPAYLEKAANTFK---AKGAHVIIASQTPNNP----WETGTFAySPNRFWGYAE----PAAEVSGVKYVDHGGYVA 196
                  ******9*************************666...888***********99....444433303444444443....6899999*****988888 PP

                  HTHCCGCHCH............TSSSB-HHHHHHHHHHH CS
                  xxxxxxxxxx............xxxxxxxxxxxxxxxxx RF
  Lipase_GDSL 174 glsgieqlka............DglHpsekgyeklaell 200
                  +   ++   +            D++H s +g + +a+++
   EEA19688.1 197 SI--FK---DlgvttvdsyypnDHTHTSVAGAKVVAQAF 230
                  87..22...2333556677777*************9986 PP

>> DUF1330  Domain of unknown function (DUF1330)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.0    0.0012       5.3      23      58 ..      57      92 ..      46      96 .. 0.89
   2 ?    3.6   0.0     0.019        86      16      41 ..     132     157 ..     128     163 .. 0.88

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0012
     DUF1330 23 aeaalakyggrflvrggkvevlEGdeeptrlvvieF 58
                +++a+a  ++r  +r+g+++++  + +p ++vvieF
  EEA19688.1 57 SNQAIAGRSARSYAREGHFNTIASEIQPGDFVVIEF 92
                578999999*************************** PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.019
     DUF1330  16 ykeYaalaeaalakyggrflvrggkv 41 
                 + +Y ++a++++++ g++++++++++
  EEA19688.1 132 FPAYLEKAANTFKAKGAHVIIASQTP 157
                 568****************9998876 PP

>> NLPC_P60  NlpC/P60 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.0   0.00028       1.3       8      62 ..      35      92 ..      21     101 .. 0.75
   2 ?    0.8   0.0      0.11   4.8e+02      13      38 ..     188     213 ..     173     235 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00028
                --BTTEB-HHHHHHHHHHTTT----SSHHHH...CCCSEE..EEGGG--TTEEEEESG CS
    NLPC_P60  8 GkspsgfDCsglvryafakagielprssgeq...eaagkkkeiskselkrGDLvffkt 62
                G+ +sg+D +g   +++ + +++ +  +g+    +a + + + ++se+++GD+v+++ 
  EEA19688.1 35 GGGGSGTDGWGQYIASYLSLNVSNQAIAGRSarsYAREGHFNTIASEIQPGDFVVIEF 92
                4455699999988888887777655544444444666666679***********9986 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.11
                 EB-HHHHHHHHHHTTT----SSHHHH CS
    NLPC_P60  13 gfDCsglvryafakagielprssgeq 38 
                  +D  g+v ++f++ g++  +s +  
  EEA19688.1 188 YVDHGGYVASIFKDLGVTTVDSYYPN 213
                 57889999999999999887776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (255 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       437  (0.0243739); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.43
# Mc/sec: 1790.21
//
Query:       EEA19689.1  [L=249]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.3e-30  104.4  16.0    3.3e-30  104.4  16.0    2.9  3  PP28      Casein kinase substrate phosphoprotein PP28
  ------ inclusion threshold ------
        1.6    8.0  45.4       0.11   11.8  11.2    2.1  2  Nop53     Nop53 (60S ribosomal biogenesis)


Domain annotation for each model (and alignments):
>> PP28  Casein kinase substrate phosphoprotein PP28
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    3.8   3.8    0.0085        77      20      49 ..      58      95 ..      40      98 .. 0.65
   2 !  104.4  16.0   3.7e-34   3.3e-30       1      85 []     125     212 ..     125     212 .. 0.92
   3 ?   -0.8   1.3      0.24   2.2e+03      22      37 ..     216     232 ..     211     241 .. 0.53

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.0085
        PP28 20 e........kkaekpkelsRrEreaiekqkakeryekl 49
                e        +++ +p+e++R +r a+ k+k+++  +k 
  EEA19689.1 58 EssddgapgTSKVAPEEMTREQRKAAAKAKKEAAIRKR 95
                13445667666667889999999888888887777665 PP

  == domain 2  score: 104.4 bits;  conditional E-value: 3.7e-34
        PP28   1 NPNrvkkkknqklaealdee...kkaekpk.elsRrEreaiekqkakeryeklhaegkTeeakaDLaRLalireqReeaaakreaekee 85 
                 NPN+++k+++q++a +   +   k + k++ +lsRrErea+e+q+a+ery+klh egkT+ea+aD++RL+l+re+Re+++a+reaekee
  EEA19689.1 125 NPNHSAKSRSQAMAPPPVVDappK-KPKNTeQLSRREREALEAQQARERYMKLHMEGKTDEARADMERLKLVRERREAEKARREAEKEE 212
                 9*************9877777854.445555********************************************************96 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 0.24
        PP28  22 kaekpk.elsRrEreai 37 
                 ++++++ e+s rE+   
  EEA19689.1 216 QQQARQdEISEREKKLR 232
                 23333336666665444 PP

>> Nop53  Nop53 (60S ribosomal biogenesis)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8  11.2   1.2e-05      0.11     242     306 ..      41      96 ..      22     101 .. 0.62
   2 ?    2.3  26.1    0.0095        86     247     361 ..     111     233 ..      98     240 .. 0.46

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 1.2e-05
       Nop53 242 ekdegleeeeeeeeeeeeeeeeeeeesee.eeklnapvkkkpkrKTkaqRnkekrrkeeekeekee 306
                  +d      e ++eee++++eeee +s++ +  ++   k++p+ +T++qR+ ++++k+e + +k++
  EEA19689.1  41 PED------ETSSEEEDDSSEEEE-SSDDgAPGTS---KVAPEEMTREQRKAAAKAKKEAAIRKRN 96 
                 233......222222222232222.2222233344...8899****************99888765 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.0095
       Nop53 247 leeeeeeeeeeeeeeeeeeeesee..........eeklnapvkkkpkrKTkaqRn..kekrrkeeekeekeekkekkkeaqlerlkeikkevaekeker 333
                 ++e+e++++e+ +++ + +    +               ++++k++++  +++R+   +++++e+  +   e k  + +a++erlk ++++ ++++++r
  EEA19689.1 111 EDEDEDDDDEALPANPNHSA---KsrsqamapppVVDAPPKKPKNTEQLSRREREalEAQQARERYMKLHMEGKTDEARADMERLKLVRERREAEKARR 206
                 11222222222222222222...1233345664433333334444444444444422233333334445556666677889999998877765555555 PP

       Nop53 334 aeaaearkkekrkkkaekkklkrrklgk 361
                 ++++e+r  +++++++++ + + +kl  
  EEA19689.1 207 EAEKEER-DAQQQARQDEISEREKKLRE 233
                 5544444.44444455555555555543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (249 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2415  (0.134698); expected 358.6 (0.02)
Passed bias filter:                      652  (0.0363657); expected 358.6 (0.02)
Passed Vit filter:                       128  (0.00713927); expected 17.9 (0.001)
Passed Fwd filter:                        49  (0.002733); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.90u 0.36s 00:00:01.26 Elapsed: 00:00:00.47
# Mc/sec: 1581.61
//
Query:       EEA19690.1  [L=604]
Description: integral membrane protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.1e-86  287.8   9.4    7.4e-86  287.3   9.4    1.2  1  UNC-50    UNC-50 family
    1.1e-26   94.4   0.0    1.6e-26   93.8   0.0    1.3  1  PhyH      Phytanoyl-CoA dioxygenase (PhyH)


Domain annotation for each model (and alignments):
>> UNC-50  UNC-50 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  287.3   9.4   8.3e-90   7.4e-86       1     214 [.     350     592 ..     350     595 .. 0.97

  Alignments for each domain:
  == domain 1  score: 287.3 bits;  conditional E-value: 8.3e-90
      UNC-50   1 vlrrlfkfkqlDfetAlwemlhLiiaPkkvyrsiyyrkqtknqyaRdDPafliLlvlllllsaiawglayssslleilklilvmvlvdfllvglliatv 99 
                 +++rlfkf+q+Dfe+A+wem++L+iaPkkv++s+yy+ +tkn+++R+DP+f++Ll+++lll+a+awglays+s+ +i++l + +v+v+f++++l+i+t+
  EEA19690.1 350 FFKRLFKFPQMDFEMAIWEMTSLLIAPKKVFKSMYYHVKTKNTWHRPDPSFTYLLSFFLLLTALAWGLAYSPSFGSIFRLSILFVFVHFIGTSLFISTI 448
                 79************************************************************************************************* PP

      UNC-50 100 lwllvnrlllksek...........................seqdvewaYcFDvhlnaflpilvllyvlqllllplilkkk..fvslllgntlylvaig 169
                  +++v r++  +                             +++++e++YcFDv+ +af+p+++ lyv+q+lllpl++++   f+ ++lgntlyl a++
  EEA19690.1 449 AYFIVGRIFGPNGAaasltglsrgsrmprrgaaqglfaqpgEKEHIEFGYCFDVSNRAFFPLYLHLYVIQFLLLPLLTRNPpnFLTTFLGNTLYLSALL 547
                 **********666667788888889999999**********************************************998888**************** PP

      UNC-50 170 yYfyitflGYnalpflkktevlllpllllavlylitlllgfnvak 214
                 yY+yitflGYnalpfl++te+lllp+l+l +l+l++l++g+nv +
  EEA19690.1 548 YYTYITFLGYNALPFLHNTELLLLPILVLSILWLVSLIAGWNVIT 592
                 ******************************************965 PP

>> PhyH  Phytanoyl-CoA dioxygenase (PhyH)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.8   0.0   1.8e-30   1.6e-26       3     211 .]      34     215 ..      32     215 .. 0.79

  Alignments for each domain:
  == domain 1  score: 93.8 bits;  conditional E-value: 1.8e-30
                 HHSEEEETTSS-HHHHHHHHHHHHHHHHHCHTTCCSEEEEECEEESTTCCCEECCCHHCHHHHTTHHHHHHHHHHHHTSCEEEEEEEEEEEEEEEE-TT CS
        PhyH   3 edGylviegflsaeevealraeiealldralesgdkidfffeekaaadedglleksinkvghflhprkvadlvrailgqdvyvaavlqsmyqdifkqpk 101
                 ++Gy++++++l++e v++lr+e++++     e++   + +fe++ + +   ll ks+ + +  l + +v +l + +l  + y      s     + q +
  EEA19690.1  34 QNGYVALDNLLTEEDVQSLREEVDRM---TGENPRTGRHMFEGRDTVRIYSLLNKSRKFDKCCLFD-RVLALNEYFLM-KGY----TISAT--STIQIN 121
                 89***********************8...6666666666777766666667773555555555554.44444444443.444....45555..888999 PP

                 TCB-EEEEE-SGGGST.EES.GCCEEEEEEESS-B-TTBT-EEEETTGGGS-CCGTCCHHCSGCCTTSCCCTTTGHGSCEEEE.BTTTEEEEEETTSEE CS
        PhyH 102 iGgevqpwHqDstflp.tdp.eesvvgvwialedateenGclrfiPGSHkweegplrrrlpeddteaeddeakkedeeeavpvevkaGdavlfhgrllH 198
                 +G++ q  H+D+ + +  +p ++  v+++ia++d+t+enG++ ++PGSH+w+ +       + +t+           eeavp++ kaG+++ f g+++H
  EEA19690.1 122 PGEKPQLFHHDDGYTYlPRPrPPMGVAIMIAIDDFTAENGATLMVPGSHLWDSK-------RRPTM-----------EEAVPMVGKAGTVFYFLGTTWH 202
                 99999******999997555789****************************555.......23344...........569******************* PP

                 EE-TB.SSSXEEE CS
        PhyH 199 gsgaNrsdksRra 211
                  +g N+++k+Rra
  EEA19690.1 203 CGGSNMTNKPRRA 215
                 ***********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (604 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       578  (0.0322383); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.27s 00:00:00.86 Elapsed: 00:00:00.43
# Mc/sec: 4191.00
//
Query:       EEA19691.1  [L=549]
Description: hypothetical protein PMAA_004700 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.4e-08   33.7   0.7    2.4e-08   33.7   0.7    2.2  2  CorA           CorA-like Mg2+ transporter protein
  ------ inclusion threshold ------
      0.065   13.0   0.2       0.15   11.8   0.2    1.6  1  Arg_repressor  Arginine repressor, DNA binding domain
      0.074   11.7   1.0       0.11   11.2   1.0    1.2  1  EMP70          Endomembrane protein 70
      0.084   12.7   2.5       0.13   12.1   1.2    1.9  2  HSBP1          Heat shock factor binding protein 1
       0.17   10.6   0.0       0.17   10.6   0.0    2.0  2  DUF2207        Predicted membrane protein (DUF2207)
        3.4    6.3   5.1         12    4.5   5.3    1.8  2  Presenilin     Presenilin
        3.9    6.7   5.8         10    5.4   5.8    1.7  1  DUF4407        Domain of unknown function (DUF4407)
        5.6    7.3   9.2       0.26   11.6   1.6    2.6  3  DUF349         Domain of Unknown Function (DUF349)


Domain annotation for each model (and alignments):
>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1      0.53   1.2e+03     103     142 ..     168     207 ..     150     221 .. 0.66
   2 !   33.7   0.7   1.1e-11   2.4e-08     147     290 ..     282     444 ..     257     448 .. 0.58

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.53
        CorA 103 gkpkspgellyrlldeivdrlfellekleeeldeledele 142
                 +++ksp+e+++  +++ +d+ + l e    ++++  +e +
  EEA19691.1 168 HGDKSPFEIFADSINRAADSENSLFERFVNQVERNKNESR 207
                 5667777777777777777766666666666555555554 PP

  == domain 2  score: 33.7 bits;  conditional E-value: 1.1e-11
        CorA 147 keilrelaqlrrrlvklrralapnrevlk.........rllakaddkllddedkeylrdlldeler...........llemlealrerles...lqdty 222
                 +++l+e+ +++ +l  ++ ++a+++ v +         r+la ++++l+++       d+l+ele            + ++l+  ++ ++    + +  
  EEA19691.1 282 AKLLGEVKDIQDELHMFKAVVADQESVWNtltglggndRRLA-ENKSLMERGS----ADILEELEEmnrlvdsietsVKDTLNLEQNGINIteaMVSRQ 375
                 567777778888888888888888888875555555553333.2333333222....222222222222333333366666666665554300033444 PP

        CorA 223 ssllserlNrvmkvLTvltaiflPlTlitGiyGmNfkglP.....elewsygypfvlllglmallailllfwf 290
                  + +s r+ r +  +T++t++flP++++t+++  N+         +l ++   +f+  + ++++++i+l +++
  EEA19691.1 376 LTEQSTRQGRSIMAFTIVTIFFLPMSFLTSMFALNVTSFQhdasgNLLYQP--TFI--FPIIFCVSIGLGIMI 444
                 4444555******************************65544433222333..333..444444444444433 PP

>> Arg_repressor  Arginine repressor, DNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.2   6.9e-05      0.15      28      47 ..     359     378 ..     349     385 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 6.9e-05
                    HHHTTT----HHHHHHHHHH CS
  Arg_repressor  28 lLkeeGidvtQatvSRdLke 47 
                     L+++Gi++t a vSR L+e
     EEA19691.1 359 NLEQNGINITEAMVSRQLTE 378
                    599***************99 PP

>> EMP70  Endomembrane protein 70
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   1.0   4.8e-05      0.11     325     385 ..     383     442 ..     366     483 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 4.8e-05
       EMP70 325 ggekwkkntlltalllpgllflvffllnlilwakessgalpfgtlvlllllwflisvPlvl 385
                 +g+++   t++t ++lp+ +++ +f ln++ + +++sg l  +  ++++ + f++s+ l +
  EEA19691.1 383 QGRSIMAFTIVTIFFLPMSFLTSMFALNVTSFQHDASGNLLYQ-PTFIFPIIFCVSIGLGI 442
                 56688888*******************************9855.55677788899988765 PP

>> HSBP1  Heat shock factor binding protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0         2   4.5e+03       6      19 ..      93     106 ..      92     112 .. 0.83
   2 ?   12.1   1.2   5.8e-05      0.13      22      47 ..     333     358 ..     326     362 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 2
       HSBP1   6 vVenlLqqlqdkFq 19 
                 vVe +++ql + ++
  EEA19691.1  93 VVEGIFNQLREQME 106
                 79999999988776 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 5.8e-05
       HSBP1  22 sdqilsriDdMssriDdLEksiadlm 47 
                 s +il+ +++M + +D++E+s++d  
  EEA19691.1 333 SADILEELEEMNRLVDSIETSVKDTL 358
                 899*******************9976 PP

>> DUF2207  Predicted membrane protein (DUF2207)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   1.9      0.25   5.6e+02     315     381 ..     157     223 ..     123     236 .. 0.54
   2 ?   10.6   0.0   7.6e-05      0.17     348     423 ..     334     444 ..     258     461 .. 0.66

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.25
     DUF2207 315 ldpyEkalldlLfdkseegkslkeikkyakkskkkakkfkkalkkwksavkkkergyfdkkgkkklk 381
                 l+p + +ll++  dks  ++  ++i++ a++++++ ++f +++++ k++ ++++++  +++ k+k+k
  EEA19691.1 157 LSPLQGNLLQMHGDKSPFEIFADSINRAADSENSLFERFVNQVERNKNESRREKSKEHNNNDKQKTK 223
                 4555555555554444333335556666666555555555555555555555333333333333332 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 7.6e-05
     DUF2207 348 k....kakkfkkalkkwksavkk..............kergyfdkkgkkklkklsalglgliilglilillallllvll.................lvf 411
                 +    + +++++ +++++ +vk+                ++ +++++ ++  ++ a+ ++ i+++ + +l ++++l+++                 + +
  EEA19691.1 334 AdileELEEMNRLVDSIETSVKDtlnleqnginiteaMVSRQLTEQSTRQGRSIMAFTIVTIFFLPMSFLTSMFALNVTsfqhdasgnllyqptfiFPI 432
                 24556899999999999999999999999999999984444444444444445555555555555555666666666668899***7777766655333 PP

     DUF2207 412 llilllilllia 423
                 ++ ++++l++++
  EEA19691.1 433 IFCVSIGLGIMI 444
                 333333333333 PP

>> Presenilin  Presenilin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   5.3    0.0053        12     231     305 ..     198     270 ..     159     309 .. 0.45
   2 ?   -2.3   0.0      0.61   1.4e+03     233     236 ..     472     475 ..     429     542 .. 0.53

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.0053
  Presenilin 231 evaeseeeeeaekkkeeasesskeeeseeesseksaqsse....seeeseeesseaessaeesseekeseessesseee 305
                 +v+ +++e+++ek+ke++++++++++  ++++++          s  + +++ s+ +s++   se k see++e ++++
  EEA19691.1 198 QVERNKNESRREKSKEHNNNDKQKTKLVSKTKQQG----LkgkgS--TGKNQCSHGHSKTGDGSEAKYSEETDEMNQAN 270
                 22222222222222222222222111111111111....112111..11111111111111111111111111111111 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 0.61
  Presenilin 233 aese 236
                 ++++
  EEA19691.1 472 NPHH 475
                 1111 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   5.8    0.0045        10     103     256 ..     176     349 ..     173     356 .. 0.56

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.0045
     DUF4407 103 iFekeIdaelaeeqqeeakelkeqlaaa..ltaelaeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaake............ 187
                 iF ++I++  ++e++  ++ +++  +++  ++ e +++ +++++ ++++ ++ ++   + +  +   +++++ g + + G+g +ak             
  EEA19691.1 176 IFADSINRAADSENSLFERFVNQVERNKneSRREKSKEHNNNDKQKTKLVSKTKQQGLKGKGST--GKNQCSHGHS-KTGDGSEAKYseetdemnqane 271
                 7888887777666665544443333333333344444444444444444444444333333333..4444555544.6777777776555555555444 PP

     DUF4407 188 .....kkaqldaaqaelaelkakld....................atarlaalraelaeleaerakeraasqaaaaaddGllarlealdrltke 256
                      +                  d                      a++++  ++l++l  + ++ ++++  ++++++++l++le ++rl ++
  EEA19691.1 272 hedweAIY----------------DaakllgevkdiqdelhmfkaVVADQESVWNTLTGLGGNDRRLAENKSLMERGSADILEELEEMNRLVDS 349
                 44444333................2444444444444555587776777777777888887777777777788888999999999999998765 PP

>> DUF349  Domain of Unknown Function (DUF349)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   1.6   0.00012      0.26       6      44 ..     192     230 ..     189     243 .. 0.90
   2 ?   -0.9   0.2      0.91     2e+03      27      63 ..     266     292 ..     255     302 .. 0.45
   3 ?   -3.4   0.0       5.6   1.3e+04      38      47 ..     336     345 ..     334     359 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00012
      DUF349   6 FraacdafferrkahfeeqdaereenlekKealieeaea 44 
                 F+  ++++++++++ + e+ +e+ +n ++K++l+ + ++
  EEA19691.1 192 FERFVNQVERNKNESRREKSKEHNNNDKQKTKLVSKTKQ 230
                 78889*****************************99887 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.91
      DUF349  27 ereenlekKealieeaealaksttdwksa......tkrlkelq 63 
                 + ++n                  +dw++         ++k++q
  EEA19691.1 266 MNQANE---------------H-EDWEAIydaaklLGEVKDIQ 292
                 333332...............2.24433322222244444444 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 5.6
      DUF349  38 lieeaealak 47 
                 ++ee+e+++ 
  EEA19691.1 336 ILEELEEMNR 345
                 6777777633 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (549 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1751  (0.097663); expected 358.6 (0.02)
Passed bias filter:                      591  (0.0329634); expected 358.6 (0.02)
Passed Vit filter:                        71  (0.00396006); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.69u 0.26s 00:00:00.95 Elapsed: 00:00:00.45
# Mc/sec: 3648.66
//
Query:       EEA19692.1  [L=1096]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.4e-87  287.6  15.4    4.9e-14   52.7   0.3    9.0 10  Ank_2      Ankyrin repeats (3 copies)
      2e-73  239.9   3.4      2e-05   24.8   0.0   16.4 16  Ank        Ankyrin repeat
    2.8e-67  222.3  10.2    9.1e-08   32.5   0.0   14.7 16  Ank_4      Ankyrin repeats (many copies)
    4.4e-60  199.0  11.3    1.4e-06   28.5   0.2   13.5 13  Ank_5      Ankyrin repeats (many copies)
    1.6e-55  178.6   1.1    2.3e-05   24.4   0.0   16.8 17  Ank_3      Ankyrin repeat
  ------ inclusion threshold ------
       0.15   12.1   0.0        1.7    8.8   0.0    2.7  3  DUF5624    Domain of unknown function (DUF5624)


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.7   0.3   1.6e-17   4.9e-14       2      75 ..      62     154 ..      61     160 .. 0.78
   2 !   43.7   0.2     1e-14     3e-11       7      74 ..     156     233 ..     153     241 .. 0.78
   3 !   52.2   0.0   2.3e-17     7e-14      24      81 ..     247     310 ..     237     312 .. 0.84
   4 !   21.0   0.0   1.3e-07   0.00039      27      82 ..     315     380 ..     308     381 .. 0.74
   5 !   46.6   0.0   1.3e-15   3.8e-12      10      83 .]     364     447 ..     357     447 .. 0.86
   6 !   34.2   0.4   9.7e-12   2.9e-08      24      73 ..     414     476 ..     408     479 .. 0.76
   7 !   41.6   0.1   4.7e-14   1.4e-10      24      81 ..     448     517 ..     442     519 .. 0.78
   8 !   33.4   0.0   1.7e-11     5e-08       8      81 ..     467     553 ..     462     554 .. 0.76
   9 !   38.5   0.0   4.4e-13   1.3e-09      11      81 ..     540     610 ..     526     611 .. 0.85
  10 !    5.3   0.0    0.0099        29      53      80 ..     740     766 ..     701     781 .. 0.71

  Alignments for each domain:
  == domain 1  score: 52.7 bits;  conditional E-value: 1.6e-17
       Ank_2   2 hlAakngnlelvklLl.egadpn....k.ngktaLhyAakngnleivklLle..h...........adndgrtpLhyAarsghleivklLlek 75 
                   Aa++gn e+v+ Ll ++ +++    + +g++aLh+Aak+g+ ++v+ Ll+  +            dn+g+t+Lh+A++++  e+v+ Ll+ 
  EEA19692.1  62 LAAARDGNEEVVRDLLqKEEEIKinatDvDGRSALHLAAKSGHQKVVQELLKtsNrigiihqlwnlKDNYGETALHLASSYDWKEVVQELLNA 154
                 457778999*******85544444254389*********************95515666668866555***********99999*******42 PP

  == domain 2  score: 43.7 bits;  conditional E-value: 1e-14
       Ank_2   7 ngnlelvklLl.egadpnkngktaLhyAakngnleivklLleh.............adndgrtpLhyAarsghleivklLle 74 
                 +g +e+++ Ll ++++    g+taLh+A  +g++e+v+ Ll++              +n+g t+Lh+A++ gh+e++k Ll+
  EEA19692.1 156 YG-TEIINDLLiSKTK---SGRTALHLASAGGYKEVVQELLNAsdrtgttkdllisKENEGSTALHLASWRGHEEAIKELLN 233
                 44.5788888845555...57********************9556667665555433399*********99**********4 PP

  == domain 3  score: 52.2 bits;  conditional E-value: 2.3e-17
       Ank_2  24 k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinl 81 
                 + +g+taLh+A+k+ + e vk Ll+       ++ +g+tpL+ A++++h+ iv+lL+e+gadi++
  EEA19692.1 247 DeDGRTALHIACKGRD-ESVKVLLDRkaeislQTANGKTPLMEAIWHSHESIVELLVENGADIKT 310
                 248**********876.99*****955567665589**************************975 PP

  == domain 4  score: 21.0 bits;  conditional E-value: 1.3e-07
       Ank_2  27 ktaLhyAakng.nl.eivklLleh......adndgrtpLhyAars...ghleivklLlekgadinlk 82 
                  ++L +Aa +g ++ +iv++Ll++       d dg+ p+h A +     +l +vklL+ +ga+++++
  EEA19692.1 315 YSIL-TAAYYGpKTdKIVQYLLDKdldvneKDPDGWAPIHTALWVksdASLAVVKLLISRGANPEAQ 380
                 4444.566666455589*****988674444499********966654489*******99**99887 PP

  == domain 5  score: 46.6 bits;  conditional E-value: 1.3e-15
       Ank_2  10 lelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinlkd 83 
                 l +vklL+  ga+p+  + ++kt+Lh+A ++ n e+++l+le+      ad++g tpLh+ a+ +++e+++lL+ek  +++++d
  EEA19692.1 364 LAVVKLLIsRGANPEaqNsWKKTPLHLALEERNQETIRLILENsqnvdiADEEGLTPLHVGAERQNEEAIELLVEKSTNLEATD 447
                 469*****9999998853799********************977676666699*********99**********9988887776 PP

  == domain 6  score: 34.2 bits;  conditional E-value: 9.7e-12
       Ank_2  24 k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAars......ghleivklLl 73 
                 + +g+t+Lh+ a+++n+e+++lL+e+      +d++grt+LhyA+++      +   iv  Ll
  EEA19692.1 414 DeEGLTPLHVGAERQNEEAIELLVEKstnleaTDKKGRTALHYAIQNkkvnksNCKSIVTTLL 476
                 348*********************97767776669**********996554433566666666 PP

  == domain 7  score: 41.6 bits;  conditional E-value: 4.7e-14
       Ank_2  24 kngktaLhyAakn......gnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinl 81 
                 k+g+taLhyA++n      +++ iv +Ll++       + dg+tpLh+A+ +g leivkl l ++ ++n+
  EEA19692.1 448 KKGRTALHYAIQNkkvnksNCKSIVTTLLNNytpidaPNADGETPLHWAVLYGGLEIVKLILRRNPNVNA 517
                 379*********944433333347*****977896665599***********99********77778876 PP

  == domain 8  score: 33.4 bits;  conditional E-value: 1.7e-11
       Ank_2   8 gnlelvklLleg.adpn..k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAars....ghleivklLlekgadinl 81 
                 +  ++v  Ll++ + ++  + +g+t+Lh+A+ +g leivkl+l         d + +t+Lh A r+    ++ +i + Ll k+adi +
  EEA19692.1 467 NCKSIVTTLLNNyTPIDapNaDGETPLHWAVLYGGLEIVKLILRRnpnvnaYDHSKETALHKAHRCfvkeDRGRITEELL-KKADIGA 553
                 4347999999552333443369*********************85566445558899******99888876779999999.5588876 PP

  == domain 9  score: 38.5 bits;  conditional E-value: 4.4e-13
       Ank_2  11 elvklLlegadpn.k..ngktaLhyAakngnleivklLlehadndgrtpLhyAarsghleivklLlekgadinl 81 
                  + + Ll++ad++ k   g+taLh A ++g   + + ++++ d    tpLh+A+++gh +++k+Ll++ ad+++
  EEA19692.1 540 RITEELLKKADIGaKcdAGQTALHKASEAG---CTEEFIDARDTFTFTPLHLASKNGHGDTIKILLDYRADVEA 610
                 5889999898988734699**********9...7789**9988999********************99999976 PP

  == domain 10  score: 5.3 bits;  conditional E-value: 0.0099
       Ank_2  53 grtpLhyAarsghleivklLlekgadin 80 
                   ++L++Aa +g++ +v +Ll  ++++ 
  EEA19692.1 740 DDSVLQWAAYHGYYVVVYWLLR-NSEPR 766
                 4567778887788777777773.34444 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.028        83       9      31 ..      64      89 ..      61      90 .. 0.72
   2 !   17.0   0.0   1.9e-06    0.0058       1      23 [.      91     114 ..      91     130 .. 0.84
   3 !   18.1   0.0   8.8e-07    0.0026       1      23 [.     131     155 ..     131     165 .. 0.84
   4 !   18.5   0.0   6.6e-07     0.002       2      25 ..     172     194 ..     171     202 .. 0.87
   5 !   18.2   0.0   8.1e-07    0.0024       2      23 ..     212     235 ..     211     248 .. 0.77
   6 !   18.5   0.0   6.6e-07     0.002       1      31 [.     249     279 ..     249     280 .. 0.87
   7 !   21.2   0.0   9.4e-08   0.00028       1      28 [.     281     309 ..     281     314 .. 0.88
   8 ?   -1.8   0.0       1.8   5.3e+03      16      27 ..     329     341 ..     319     345 .. 0.64
   9 !   14.2   0.0   1.5e-05     0.044       1      31 [.     347     381 ..     347     382 .. 0.78
  10 !   10.6   0.0   0.00021      0.64       3      31 ..     385     414 ..     384     415 .. 0.87
  11 !   11.5   0.0   0.00011      0.32       2      32 .]     417     448 ..     416     448 .. 0.92
  12 !   15.8   0.0   4.9e-06     0.015       2      23 ..     450     478 ..     449     487 .. 0.79
  13 !   24.8   0.0   6.5e-09     2e-05       1      31 [.     488     519 ..     488     520 .. 0.87
  14 ?    1.3   0.0      0.19   5.6e+02       4      29 ..     524     553 ..     522     556 .. 0.71
  15 ?    5.0   0.0     0.012        36       2      22 ..     558     575 ..     557     580 .. 0.86
  16 !   20.1   0.0   2.1e-07   0.00064       3      29 ..     583     610 ..     583     611 .. 0.92

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.028
                HHHHTTHHHHHHHH.TT..TSTTCBT CS
         Ank  9 AatngkkriiklLL.hG..Anlnald 31
                Aa+ g+++++++LL +     +na+d
  EEA19692.1 64 AARDGNEEVVRDLLqKEeeIKINATD 89
                668899********533345688888 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 1.9e-06
                 TSBBHHHHHHHHTTHHHHHHHH.T CS
         Ank   1 dGnTPLHlAatngkkriiklLL.h 23 
                 dG+++LHlAa  g+  ++++LL  
  EEA19692.1  91 DGRSALHLAAKSGHQKVVQELLkT 114
                 8*********999999*****943 PP

  == domain 3  score: 18.1 bits;  conditional E-value: 8.8e-07
                 TSBBHHHHHHHHTTHHHHHHHH..T CS
         Ank   1 dGnTPLHlAatngkkriiklLL..h 23 
                 +G T+LHlA++++ k+++++LL  +
  EEA19692.1 131 YGETALHLASSYDWKEVVQELLnaS 155
                 69********************532 PP

  == domain 4  score: 18.5 bits;  conditional E-value: 6.6e-07
                 SBBHHHHHHHHTTHHHHHHHHTTT CS
         Ank   2 GnTPLHlAatngkkriiklLLhGA 25 
                 G+T+LHlA+ +g k+++++LL  A
  EEA19692.1 172 GRTALHLASAGGYKEVVQELL-NA 194
                 9********9999********.33 PP

  == domain 5  score: 18.2 bits;  conditional E-value: 8.1e-07
                 SBBHHHHHHHHTTHHHHHHHH..T CS
         Ank   2 GnTPLHlAatngkkriiklLL..h 23 
                 G T+LHlA+++g+++ ik+LL  +
  EEA19692.1 212 GSTALHLASWRGHEEAIKELLntN 235
                 89******************9532 PP

  == domain 6  score: 18.5 bits;  conditional E-value: 6.6e-07
                 TSBBHHHHHHHHTTHHHHHHHHTT.TSTTCBT CS
         Ank   1 dGnTPLHlAatngkkriiklLLhG.Anlnald 31 
                 dG+T+LH+A+  g  + +k LL++ A++ +++
  EEA19692.1 249 DGRTALHIAC-KGRDESVKVLLDRkAEISLQT 279
                 8*********.79999******6559998876 PP

  == domain 7  score: 21.2 bits;  conditional E-value: 9.4e-08
                 TSBBHHHHHHHHTTHHHHHHHH.TTTSTT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hGAnln 28 
                 +G TPL+ A++  +++i++lL+ +GA++ 
  EEA19692.1 281 NGKTPLMEAIWHSHESIVELLVeNGADIK 309
                 7*********99**********99***94 PP

  == domain 8  score: -1.8 bits;  conditional E-value: 1.8
                 HHHHHHH.TTTST CS
         Ank  16 riiklLL.hGAnl 27 
                  i+++LL +  ++
  EEA19692.1 329 KIVQYLLdKDLDV 341
                 49*****333344 PP

  == domain 9  score: 14.2 bits;  conditional E-value: 1.5e-05
                 TSBBHHHHHHHHTT...HHHHHHHH.TTTSTTCBT CS
         Ank   1 dGnTPLHlAatngk...kriiklLL.hGAnlnald 31 
                 dG+ P H A + ++   + ++klL+ +GAn+ a++
  EEA19692.1 347 DGWAPIHTALWVKSdasLAVVKLLIsRGANPEAQN 381
                 8999999986444444466******779*****98 PP

  == domain 10  score: 10.6 bits;  conditional E-value: 0.00021
                 BBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   3 nTPLHlAatngkkriiklLL.hGAnlnald 31 
                  TPLHlA  + + + i+l+L ++ n+++ d
  EEA19692.1 385 KTPLHLALEERNQETIRLILeNSQNVDIAD 414
                 5*****99888899***9998788998876 PP

  == domain 11  score: 11.5 bits;  conditional E-value: 0.00011
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlnaldn 32 
                 G TPLH+ a + +++ i+lL+ ++ nl a+d+
  EEA19692.1 417 GLTPLHVGAERQNEEAIELLVeKSTNLEATDK 448
                 99*******99**********8899****995 PP

  == domain 12  score: 15.8 bits;  conditional E-value: 4.9e-06
                 SBBHHHHHHHHTT......HHHHHHHH.T CS
         Ank   2 GnTPLHlAatngk......kriiklLL.h 23 
                 G+T+LH+A++n+k      k+i+  LL +
  EEA19692.1 450 GRTALHYAIQNKKvnksncKSIVTTLLnN 478
                 9********8888999999*****99943 PP

  == domain 13  score: 24.8 bits;  conditional E-value: 6.5e-09
                 TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hGAnlnald 31 
                 dG TPLH+A+ +g+++i+kl+L +  n+na d
  EEA19692.1 488 DGETPLHWAVLYGGLEIVKLILrRNPNVNAYD 519
                 8******************9995457888855 PP

  == domain 14  score: 1.3 bits;  conditional E-value: 0.19
                 BHHHHH..H....HHTTHHHHHHHHTTTSTTC CS
         Ank   4 TPLHlA..a....tngkkriiklLLhGAnlna 29 
                 T+LH A  +     +g  ri+++LL+ A++ a
  EEA19692.1 524 TALHKAhrCfvkeDRG--RITEELLKKADIGA 553
                 9999864437766444..69999997788865 PP

  == domain 15  score: 5.0 bits;  conditional E-value: 0.012
                 SBBHHHHHHHHTTHHHHHHHH CS
         Ank   2 GnTPLHlAatngkkriiklLL 22 
                 G T+LH A+  g   ++++++
  EEA19692.1 558 GQTALHKASEAG---CTEEFI 575
                 99*******999...999888 PP

  == domain 16  score: 20.1 bits;  conditional E-value: 2.1e-07
                 BBHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   3 nTPLHlAatngkkriiklLL.hGAnlna 29 
                 +TPLHlA+ ng+ + ik LL ++A++ a
  EEA19692.1 583 FTPLHLASKNGHGDTIKILLdYRADVEA 610
                 7*******99**********779**987 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.5   0.0   1.2e-09   3.4e-06       5      55 .]      61     112 ..      59     112 .. 0.87
   2 !   23.3   0.1   2.4e-08   7.2e-05       2      44 ..      93     141 ..      93     152 .. 0.81
   3 !   22.5   0.0   4.1e-08   0.00012       3      55 .]     134     192 ..     132     192 .. 0.85
   4 !   12.5   0.0   5.8e-05      0.17      30      55 .]     207     232 ..     199     232 .. 0.84
   5 !   24.0   0.0   1.4e-08   4.2e-05       2      46 ..     213     261 ..     212     263 .. 0.85
   6 !   32.5   0.0     3e-11   9.1e-08       1      55 []     250     302 ..     250     302 .. 0.97
   7 !   11.6   0.0   0.00011      0.32      15      44 ..     329     357 ..     314     360 .. 0.89
   8 !   16.3   0.0   3.7e-06     0.011      12      44 ..     362     393 ..     358     398 .. 0.89
   9 !   31.7   0.0   5.3e-11   1.6e-07       3      55 .]     386     437 ..     386     437 .. 0.97
  10 !   31.8   0.0   5.2e-11   1.6e-07       2      48 ..     418     463 ..     417     465 .. 0.95
  11 !   28.8   0.0   4.4e-10   1.3e-06       1      54 [.     450     508 ..     450     509 .. 0.94
  12 !   22.1   0.0   5.7e-08   0.00017       3      42 ..     491     529 ..     489     535 .. 0.96
  13 !   10.1   0.0   0.00032      0.96       4      46 ..     525     569 ..     524     574 .. 0.79
  14 !   10.7   0.0   0.00021      0.64      27      55 .]     575     602 ..     572     602 .. 0.90
  15 !    9.5   0.0   0.00051       1.5       3      29 ..     584     610 ..     582     628 .. 0.72
  16 ?    4.9   0.0     0.014        41       6      55 .]     707     760 ..     702     760 .. 0.68

  Alignments for each domain:
  == domain 1  score: 27.5 bits;  conditional E-value: 1.2e-09
       Ank_4   5 LhyaaisgrlelvrlLlek..gadinaqdnrsGetalhiAakrgnveilklLl 55 
                 L +aa +g++e+vr Ll+k   + ina+ + +G++alh Aak g+ ++++ Ll
  EEA19692.1  61 LLAAARDGNEEVVRDLLQKeeEIKINAT-DVDGRSALHLAAKSGHQKVVQELL 112
                 557889***********8833466****.****************99998776 PP

  == domain 2  score: 23.3 bits;  conditional E-value: 2.4e-08
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgad.......inaqdnrsGetalhiAak 44 
                 ++aLh aa+sg+ ++v+ Ll +          +n   +++Getalh A +
  EEA19692.1  93 RSALHLAAKSGHQKVVQELLKTSNRigiihqlWNLK-DNYGETALHLASS 141
                 689*****************7666666767777776.**********986 PP

  == domain 3  score: 22.5 bits;  conditional E-value: 4.1e-08
       Ank_4   3 taLhyaaisgrlelvrlLl..ekgad.inaq...dnrsGetalhiAakrgnveilklLl 55 
                 taLh a ++   e+v+ Ll  ++g + in     + +sG+talh A  +g++e+++ Ll
  EEA19692.1 134 TALHLASSYDWKEVVQELLnaSYGTEiINDLlisKTKSGRTALHLASAGGYKEVVQELL 192
                 89*****************55468888555554467*******************9886 PP

  == domain 4  score: 12.5 bits;  conditional E-value: 5.8e-05
       Ank_4  30 qdnrsGetalhiAakrgnveilklLl 55 
                 ++ ++G talh A +rg+ e++k Ll
  EEA19692.1 207 SKENEGSTALHLASWRGHEEAIKELL 232
                 56788*****************9886 PP

  == domain 5  score: 24.0 bits;  conditional E-value: 1.4e-08
       Ank_4   2 ltaLhyaaisgrlelvrlLl..ekgad...inaqdnrsGetalhiAakrg 46 
                 +taLh a   g++e+++ Ll  ++g     +n   +++G+talhiA+k+ 
  EEA19692.1 213 STALHLASWRGHEEAIKELLntNYGLRseyLNLK-DEDGRTALHIACKGR 261
                 689999999***********55457777777776.************975 PP

  == domain 6  score: 32.5 bits;  conditional E-value: 3e-11
       Ank_4   1 eltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++taLh a+ +gr e+v+ Ll+++a+i  q  ++G t+l  A+++++ +i++lL+
  EEA19692.1 250 GRTALHIAC-KGRDESVKVLLDRKAEISLQ-TANGKTPLMEAIWHSHESIVELLV 302
                 589******.********************.**********************96 PP

  == domain 7  score: 11.6 bits;  conditional E-value: 0.00011
       Ank_4  15 elvrlLlekgadinaqdnrsGetalhiAak 44 
                 ++v++Ll+k+ d+n+ d++ G+ ++h A++
  EEA19692.1 329 KIVQYLLDKDLDVNEKDPD-GWAPIHTALW 357
                 679*************666.******9985 PP

  == domain 8  score: 16.3 bits;  conditional E-value: 3.7e-06
       Ank_4  12 grlelvrlLlekgadinaqdnrsGetalhiAak 44 
                   l +v+lL+++ga++ aq n+   t+lh A+ 
  EEA19692.1 362 ASLAVVKLLISRGANPEAQ-NSWKKTPLHLALE 393
                 56789**************.***********94 PP

  == domain 9  score: 31.7 bits;  conditional E-value: 5.3e-11
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 t+Lh a ++ + e++rl+le+ ++++   +++G+t+lh +a r n e+++lL+
  EEA19692.1 386 TPLHLALEERNQETIRLILENSQNVDIA-DEEGLTPLHVGAERQNEEAIELLV 437
                 79*************************8.**********************96 PP

  == domain 10  score: 31.8 bits;  conditional E-value: 5.2e-11
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnv 48 
                 lt+Lh  a+ +++e+++lL+ek  ++ a+ ++ G+talh+A+++ +v
  EEA19692.1 418 LTPLHVGAERQNEEAIELLVEKSTNLEAT-DKKGRTALHYAIQNKKV 463
                 89***************************.************99765 PP

  == domain 11  score: 28.8 bits;  conditional E-value: 4.4e-10
       Ank_4   1 eltaLhyaai......sgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54 
                 ++taLhya++      s++  +v  Ll++   i+a  n++Get+lh A++ g +ei+kl 
  EEA19692.1 450 GRTALHYAIQnkkvnkSNCKSIVTTLLNNYTPIDAP-NADGETPLHWAVLYGGLEIVKLI 508
                 589************************99999***8.***************99999986 PP

  == domain 12  score: 22.1 bits;  conditional E-value: 5.7e-08
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiA 42 
                 t+Lh+a+ +g le+v+l+l +++++na  + s etalh+A
  EEA19692.1 491 TPLHWAVLYGGLEIVKLILRRNPNVNAY-DHSKETALHKA 529
                 89*****************99******9.*********99 PP

  == domain 13  score: 10.1 bits;  conditional E-value: 0.00032
       Ank_4   4 aLhyaai....sgrlelvrlLlekgadinaqdnrsGetalhiAakrg 46 
                 aLh+a      + r ++ + Ll k+adi a   + G+talh+A   g
  EEA19692.1 525 ALHKAHRcfvkEDRGRITEELL-KKADIGAK-CDAGQTALHKASEAG 569
                 6666666766777777788888.99*****9.667********8765 PP

  == domain 14  score: 10.7 bits;  conditional E-value: 0.00021
       Ank_4  27 inaqdnrsGetalhiAakrgnveilklLl 55 
                 i+a+ +   +t+lh A k+g+ + +k Ll
  EEA19692.1 575 IDAR-DTFTFTPLHLASKNGHGDTIKILL 602
                 6788.88999*************999987 PP

  == domain 15  score: 9.5 bits;  conditional E-value: 0.00051
       Ank_4   3 taLhyaaisgrlelvrlLlekgadina 29 
                 t+Lh a + g+ +++++Ll+++ad+ a
  EEA19692.1 584 TPLHLASKNGHGDTIKILLDYRADVEA 610
                 577777777777777777777777655 PP

  == domain 16  score: 4.9 bits;  conditional E-value: 0.014
       Ank_4   6 hyaai.sgrlelvrlLlekgadinaq...dnrsGetalhiAakrgnveilklLl 55 
                  +a++ + ++ l++ L  k + +n+    ++  +++ l+ Aa++g++ ++ +Ll
  EEA19692.1 707 WWAMEpERHHSLLAELKGKAKPLNKDeasLDLADDSVLQWAAYHGYYVVVYWLL 760
                 566666666667777775544444411113555999***************997 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.0   1.5e-09   4.5e-06       4      56 .]      79     139 ..      76     139 .. 0.90
   2 !   12.3   0.0   5.3e-05      0.16      10      40 ..     126     154 ..     122     158 .. 0.87
   3 !   13.4   0.0   2.5e-05     0.075      12      49 ..     168     199 ..     162     207 .. 0.81
   4 !   14.7   0.0   9.7e-06     0.029      11      43 ..     207     237 ..     202     243 .. 0.81
   5 !   26.3   0.0   2.2e-09   6.6e-06       9      53 ..     243     286 ..     238     286 .. 0.96
   6 !   14.3   0.0   1.3e-05     0.039      12      48 ..     280     314 ..     275     323 .. 0.85
   7 !    9.1   0.0   0.00053       1.6      31      56 .]     330     355 ..     328     355 .. 0.95
   8 !   22.7   0.0   3.1e-08   9.2e-05       1      55 [.     370     423 ..     370     423 .. 0.96
   9 !    8.5   0.0   0.00085       2.5       7      27 ..     441     461 ..     435     464 .. 0.81
  10 !   28.5   0.2   4.6e-10   1.4e-06       1      56 []     475     529 ..     475     529 .. 0.91
  11 !   10.0   0.0   0.00029      0.86       7      32 ..     549     574 ..     545     576 .. 0.86
  12 !   19.0   0.0   4.2e-07    0.0013      10      43 ..     576     609 ..     575     611 .. 0.90
  13 ?    2.7   0.0     0.057   1.7e+02      18      37 ..     742     764 ..     729     780 .. 0.74

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 1.5e-09
       Ank_5   4 hg.padvnrldgggntpLhvAakygaadvvrlLl.......argadlnltdsrGltaldlA 56 
                 +   + +n++d +g ++Lh+Aak g++ vv++Ll         ++ +nl+d++G+tal+lA
  EEA19692.1  79 KEeEIKINATDVDGRSALHLAAKSGHQKVVQELLktsnrigIIHQLWNLKDNYGETALHLA 139
                 55567789****************************98888889***************98 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 5.3e-05
       Ank_5  10 nrldgggntpLhvAakygaadvvrlLlarga 40 
                 n +d++g+t+Lh+A++y   +vv++Ll  +a
  EEA19692.1 126 NLKDNYGETALHLASSYDWKEVVQELL--NA 154
                 78999*************999999999..54 PP

  == domain 3  score: 13.4 bits;  conditional E-value: 2.5e-05
       Ank_5  12 ldgggntpLhvAakygaadvvrlLlargadlnltdsrG 49 
                 + + g t+Lh+A+ +g+ +vv++Ll      n+ d  G
  EEA19692.1 168 KTKSGRTALHLASAGGYKEVVQELL------NASDRTG 199
                 567889*******************......5555555 PP

  == domain 4  score: 14.7 bits;  conditional E-value: 9.7e-06
       Ank_5  11 rldgggntpLhvAakygaadvvrlLlargadln 43 
                  ++++g t+Lh+A+++g+ + +++Ll  + +++
  EEA19692.1 207 SKENEGSTALHLASWRGHEEAIKELL--NTNYG 237
                 5789999*******************..33333 PP

  == domain 5  score: 26.3 bits;  conditional E-value: 2.2e-09
       Ank_5   9 vnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltal 53 
                 +n +d++g t+Lh+A+k g+ + v++Ll+r a + l++++G+t+l
  EEA19692.1 243 LNLKDEDGRTALHIACK-GRDESVKVLLDRKAEISLQTANGKTPL 286
                 6999*************.**************************8 PP

  == domain 6  score: 14.3 bits;  conditional E-value: 1.3e-05
       Ank_5  12 ldgggntpLhvAakygaadvvrlLlargadlnltdsr 48 
                  +g+  tpL+ A+++ + ++v+lL+++gad+++  ++
  EEA19692.1 280 ANGK--TPLMEAIWHSHESIVELLVENGADIKTHSNN 314
                 4555..**************************98876 PP

  == domain 7  score: 9.1 bits;  conditional E-value: 0.00053
       Ank_5  31 vvrlLlargadlnltdsrGltaldlA 56 
                 +v++Ll+  +d n +d +G+ +++ A
  EEA19692.1 330 IVQYLLDKDLDVNEKDPDGWAPIHTA 355
                 79********************9987 PP

  == domain 8  score: 22.7 bits;  conditional E-value: 3.1e-08
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldl 55 
                 L+++g a++ +++ ++ tpLh+A + ++++ +rl+l++ ++ ++ d++Glt+l++
  EEA19692.1 370 LISRG-ANPEAQNSWKKTPLHLALEERNQETIRLILENSQNVDIADEEGLTPLHV 423
                 78899.**********************************************985 PP

  == domain 9  score: 8.5 bits;  conditional E-value: 0.00085
       Ank_5   7 advnrldgggntpLhvAakyg 27 
                  ++ ++d++g t+Lh+A+ + 
  EEA19692.1 441 TNLEATDKKGRTALHYAIQNK 461
                 68899************9865 PP

  == domain 10  score: 28.5 bits;  conditional E-value: 4.6e-10
       Ank_5   1 Llehg.padvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 Ll++  p+d  + dg+  tpLh+A+ yg +++v+l+l r+ + n++d + +tal+ A
  EEA19692.1 475 LLNNYtPIDAPNADGE--TPLHWAVLYGGLEIVKLILRRNPNVNAYDHSKETALHKA 529
                 7888889999888877..*****************************8889999876 PP

  == domain 11  score: 10.0 bits;  conditional E-value: 0.00029
       Ank_5   7 advnrldgggntpLhvAakygaadvv 32 
                 ad+ +++  g+t+Lh A+++g+ + +
  EEA19692.1 549 ADIGAKCDAGQTALHKASEAGCTEEF 574
                 889999****************9876 PP

  == domain 12  score: 19.0 bits;  conditional E-value: 4.2e-07
       Ank_5  10 nrldgggntpLhvAakygaadvvrlLlargadln 43 
                 +++d + +tpLh+A+k+g+ d +++Ll+++ad  
  EEA19692.1 576 DARDTFTFTPLHLASKNGHGDTIKILLDYRADVE 609
                 5789999************************975 PP

  == domain 13  score: 2.7 bits;  conditional E-value: 0.057
       Ank_5  18 tpLhvAakygaadvvrlLl...a 37 
                 ++L +Aa++g+  vv +Ll   +
  EEA19692.1 742 SVLQWAAYHGYYVVVYWLLrnsE 764
                 8999***************5443 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0     0.026        78       5      25 ..      60      79 ..      57      87 .. 0.81
   2 !   12.6   0.0   5.5e-05      0.16       1      23 [.      91     113 ..      91     120 .. 0.90
   3 !   13.2   0.0   3.4e-05       0.1       1      23 [.     131     153 ..     131     160 .. 0.89
   4 !    8.5   0.0    0.0011       3.4       2      23 ..     172     193 ..     171     196 .. 0.94
   5 !    6.0   0.0    0.0076        23       1      24 [.     211     235 ..     211     238 .. 0.88
   6 !   13.5   0.0   2.7e-05     0.081       1      29 [.     249     275 ..     249     277 .. 0.91
   7 !   13.8   0.0   2.2e-05     0.067       1      29 [.     281     308 ..     281     310 .. 0.95
   8 !    8.2   0.0    0.0015       4.5       3      30 ..     314     342 ..     312     343 .. 0.86
   9 ?    2.9   0.0     0.075   2.2e+02       2      30 ..     348     378 ..     347     379 .. 0.69
  10 !    6.9   0.0    0.0039        12       3      30 ..     385     411 ..     383     412 .. 0.87
  11 !    9.6   0.0   0.00052       1.5       1      28 [.     416     442 ..     416     445 .. 0.88
  12 !    7.3   0.0    0.0029       8.8       2      23 ..     450     477 ..     449     484 .. 0.71
  13 !   24.4   0.0   7.6e-09   2.3e-05       1      31 []     488     517 ..     488     517 .. 0.95
  14 ?   -3.9   0.0         6   1.8e+04       3       9 ..     523     529 ..     522     529 .. 0.86
  15 ?    4.6   0.0     0.023        67       2      16 ..     558     572 ..     557     577 .. 0.84
  16 !   15.7   0.0   5.2e-06     0.016       4      30 ..     584     609 ..     581     610 .. 0.93
  17 ?    3.3   0.0     0.056   1.7e+02       4      24 ..     742     762 ..     740     766 .. 0.89

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.026
       Ank_3  5 pLhlAarsgnleivkfLlenk 25
                 L  Aar gn e+v+ Ll+ k
  EEA19692.1 60 KLLAAARDGNEEVVRDLLQ-K 79
                6889**************9.4 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 5.5e-05
       Ank_3   1 nGetpLhlAarsgnleivkfLle 23 
                 +G+++LhlAa+sg+ ++v+ Ll+
  EEA19692.1  91 DGRSALHLAAKSGHQKVVQELLK 113
                 69*******************98 PP

  == domain 3  score: 13.2 bits;  conditional E-value: 3.4e-05
       Ank_3   1 nGetpLhlAarsgnleivkfLle 23 
                 +Get+LhlA +++  e+v+ Ll+
  EEA19692.1 131 YGETALHLASSYDWKEVVQELLN 153
                 79********************9 PP

  == domain 4  score: 8.5 bits;  conditional E-value: 0.0011
       Ank_3   2 GetpLhlAarsgnleivkfLle 23 
                 G+t+LhlA   g  e+v+ Ll+
  EEA19692.1 172 GRTALHLASAGGYKEVVQELLN 193
                 9*******************98 PP

  == domain 5  score: 6.0 bits;  conditional E-value: 0.0076
       Ank_3   1 nGetpLhlAarsgnleivkfLle.n 24 
                 +G t+LhlA   g+ e +k Ll+ n
  EEA19692.1 211 EGSTALHLASWRGHEEAIKELLNtN 235
                 599*******************944 PP

  == domain 6  score: 13.5 bits;  conditional E-value: 2.7e-05
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadv 29 
                 +G+t+Lh+A++  + + vk Ll+ + a++
  EEA19692.1 249 DGRTALHIACKGRDES-VKVLLD-RKAEI 275
                 69**************.******.88877 PP

  == domain 7  score: 13.8 bits;  conditional E-value: 2.2e-05
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadv 29 
                 nG tpL++A+ + + +iv++L+e +gad+
  EEA19692.1 281 NGKTPLMEAIWHSHESIVELLVE-NGADI 308
                 79*********************.8***9 PP

  == domain 8  score: 8.2 bits;  conditional E-value: 0.0015
       Ank_3   3 etpLhlAarsgnle..ivkfLlenkgadvn 30 
                 ++ + +Aa +g+ +  iv++Ll+ k  dvn
  EEA19692.1 314 NYSILTAAYYGPKTdkIVQYLLD-KDLDVN 342
                 677889*******668*******.999999 PP

  == domain 9  score: 2.9 bits;  conditional E-value: 0.075
       Ank_3   2 GetpLh..lAarsgnl.eivkfLlenkgadvn 30 
                 G+ p+h  l ++s+   ++vk+L+  +ga++ 
  EEA19692.1 348 GWAPIHtaLWVKSDASlAVVKLLIS-RGANPE 378
                 6667775544555555369******.9**986 PP

  == domain 10  score: 6.9 bits;  conditional E-value: 0.0039
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvn 30 
                  tpLhlA++  n e ++++le +  +v+
  EEA19692.1 385 KTPLHLALEERNQETIRLILE-NSQNVD 411
                 69***********99******.677776 PP

  == domain 11  score: 9.6 bits;  conditional E-value: 0.00052
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgad 28 
                 +G tpLh+ a+ +n e +++L+e k  +
  EEA19692.1 416 EGLTPLHVGAERQNEEAIELLVE-KSTN 442
                 599*******************9.6666 PP

  == domain 12  score: 7.3 bits;  conditional E-value: 0.0029
       Ank_3   2 GetpLhlAarsgnl......eivkfLle 23 
                 G+t+Lh+A+ + ++      +iv  Ll+
  EEA19692.1 450 GRTALHYAIQNKKVnksnckSIVTTLLN 477
                 9*********999866554336766666 PP

  == domain 13  score: 24.4 bits;  conditional E-value: 7.6e-09
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvna 31 
                 +GetpLh+A+++g leivk++l+ ++++vna
  EEA19692.1 488 DGETPLHWAVLYGGLEIVKLILR-RNPNVNA 517
                 69*********************.9999996 PP

  == domain 14  score: -3.9 bits;  conditional E-value: 6
       Ank_3   3 etpLhlA 9  
                 et+Lh A
  EEA19692.1 523 ETALHKA 529
                 7****87 PP

  == domain 15  score: 4.6 bits;  conditional E-value: 0.023
       Ank_3   2 GetpLhlAarsgnle 16 
                 G+t+Lh A ++g++e
  EEA19692.1 558 GQTALHKASEAGCTE 572
                 9**********9986 PP

  == domain 16  score: 15.7 bits;  conditional E-value: 5.2e-06
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadvn 30 
                 tpLhlA ++g+ + +k Ll+ + adv 
  EEA19692.1 584 TPLHLASKNGHGDTIKILLD-YRADVE 609
                 9*******************.9***96 PP

  == domain 17  score: 3.3 bits;  conditional E-value: 0.056
       Ank_3   4 tpLhlAarsgnleivkfLlen 24 
                 + L +Aa +g + +v +Ll+n
  EEA19692.1 742 SVLQWAAYHGYYVVVYWLLRN 762
                 789****************94 PP

>> DUF5624  Domain of unknown function (DUF5624)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       2.8   8.3e+03      26      47 ..     139     160 ..     135     168 .. 0.75
   2 ?    8.8   0.0   0.00056       1.7      29      91 ..     182     249 ..     173     258 .. 0.74
   3 ?   -1.4   0.0      0.77   2.3e+03      64      92 ..     592     620 ..     585     652 .. 0.71

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 2.8
                 TT-THHHHHHHHHHHHHHHHHH CS
     DUF5624  26 lgdeswrsaaekLlekikavre 47 
                 +++ +w++ +++Ll++   +  
  EEA19692.1 139 ASSYDWKEVVQELLNASYGTEI 160
                 45678*******9998766655 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.00056
                 THHHHHHHHHHHHHHHH...HHHH..-SS-HHHHS--GGGGGGHHHHHHHHHHHHHHHHHHHHHHHTT CS
     DUF5624  29 eswrsaaekLlekikav...revn..seelwrdkiaveafqgreekiaalvdYalslteeylervled 91 
                   +++ +++Ll++  ++   +++   +e+     +++++++g+ee+i++l++    l +eyl+   ed
  EEA19692.1 182 GGYKEVVQELLNASDRTgttKDLLisKENEGSTALHLASWRGHEEAIKELLNTNYGLRSEYLNLKDED 249
                 458888888888766651115544646666778899****************9999999999865554 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.77
                 GGGHHHHHHHHHHHHHHHHHHHHHHHTTS CS
     DUF5624  64 qgreekiaalvdYalslteeylervleda 92 
                 +g+ ++i+ l+dY  ++ +++ ++ +e +
  EEA19692.1 592 NGHGDTIKILLDYRADVEARLATTSKEPN 620
                 689999*******9999988766655443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1096 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       907  (0.0505884); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.85u 0.32s 00:00:01.17 Elapsed: 00:00:00.49
# Mc/sec: 6676.59
//
Query:       EEA19693.1  [L=323]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.7e-22   78.3   0.1    1.1e-21   77.4   0.0    1.5  2  Methyltransf_23  Methyltransferase domain
    1.6e-10   41.0   0.0    5.8e-10   39.2   0.0    1.8  1  Methyltransf_31  Methyltransferase domain
    3.8e-10   40.4   0.0    1.9e-09   38.1   0.0    2.2  2  Methyltransf_25  Methyltransferase domain
    3.1e-07   31.1   0.0    1.4e-06   29.0   0.0    2.1  1  Methyltransf_12  Methyltransferase domain
    6.8e-07   29.8   0.0      9e-06   26.3   0.0    2.3  2  Methyltransf_11  Methyltransferase domain
    0.00029   21.0   0.0    0.00044   20.4   0.0    1.3  1  FtsJ             FtsJ-like methyltransferase
     0.0093   16.0   0.4      0.087   12.9   0.1    2.3  2  TagF_N           TagF N-terminal domain, Type VI secretion sy
     0.0097   15.5   0.0      0.022   14.3   0.0    1.7  1  MTS              Methyltransferase small domain
  ------ inclusion threshold ------
      0.015   14.8   1.1      0.071   12.6   0.0    2.5  3  Methyltransf_4   Putative methyltransferase
      0.069   11.9   0.5       0.11   11.2   0.5    1.3  1  Tektin           Tektin family
       0.11   11.9   0.0       0.15   11.4   0.0    1.3  1  PrmA             Ribosomal protein L11 methyltransferase (Prm
       0.14   11.5   0.0       0.45    9.8   0.0    1.8  2  Ubie_methyltran  ubiE/COQ5 methyltransferase family
       0.19   11.6   0.1        2.2    8.2   0.0    2.2  2  TrmB             Sugar-specific transcriptional regulator Trm


Domain annotation for each model (and alignments):
>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.4   0.0     8e-25   1.1e-21      20     163 ..      83     236 ..      57     238 .. 0.85
   2 ?   -3.1   0.0       4.6   6.3e+03     146     156 ..     283     293 ..     248     298 .. 0.64

  Alignments for each domain:
  == domain 1  score: 77.4 bits;  conditional E-value: 8e-25
  Methyltransf_23  20 lraggrvLdiGcGtGillevlrengf..svtgvDlspeaveiaekakkaqkdqfdeqeaaepqgkfdlIvlrevlehvpdppellrqiatllkp 111
                        ++  vLd+G+GtG+++  +++     +v+g+Dlsp++ +   ++++ ++   d ++ +  + kfd+I++r + ++++d+  ll+q+ ++l++
       EEA19693.1  83 PHPPRHVLDFGTGTGSWAIDFADLHPdsHVVGIDLSPIQPSN--TPPNCRFFVDDIESPWTFDSKFDFIHARAMSGSIRDWDTLLQQALENLNE 174
                      467889***************88866679*********9998..69999999999*************************************** PP

  Methyltransf_23 112 gGylllseplasl.......kedrllldw.lylvpag.rhi.sffsarslkelleeaGlevv 163
                      +G+++l+e+ a         +++++++ w + l++a+ r++  + s ++lk  le+ G+ +v
       EEA19693.1 175 DGVIELQEYEAAYksddgtlERTEAIRTWqRQLNEASeRVGqPMNSVETLKARLEKCGFVDV 236
                      ********9877678888888888889994455555555557888999***********877 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 4.6
  Methyltransf_23 146 fsarslkelle 156
                      +s++++++l+e
       EEA19693.1 283 WSSDEMRQLME 293
                      66677777776 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.2   0.0   4.2e-13   5.8e-10       6     132 ..      88     203 ..      83     227 .. 0.82

  Alignments for each domain:
  == domain 1  score: 39.2 bits;  conditional E-value: 4.2e-13
  Methyltransf_31   6 rvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielArenaqklgldnveFeqgdiee.leklledekfDlilsnevlnaladpdkileeie 98 
                      +vlD G+GtG  ++ +a  l p+++vvGiD s+  i+ +++        n++F + die+     +  +kfD+i++++    + d d  l+++ 
       EEA19693.1  88 HVLDFGTGTGSWAIDFA-DLHPDSHVVGIDLSP--IQPSNT------PPNCRFFVDDIESpWT--FD-SKFDFIHARAMSGSIRDWDTLLQQAL 169
                      79***************.889***********9..788877......689**********666..55.9************************* PP

  Methyltransf_31  99 rvlkpggilliedprllaelpakveeeskayevv 132
                      ++l+++g++ ++++ ++++ ++   e  +a +++
       EEA19693.1 170 ENLNEDGVIELQEYEAAYKSDDGTLERTEAIRTW 203
                      *************996666664444444333333 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.1   0.0   1.4e-12   1.9e-09       1      97 []      89     176 ..      89     176 .. 0.86
   2 ?   -1.7   0.0       3.5   4.9e+03      32      62 ..     205     235 ..     198     243 .. 0.73

  Alignments for each domain:
  == domain 1  score: 38.1 bits;  conditional E-value: 1.4e-12
                      EEEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHHTTTTEEEEESBCCGBSSSTTTEEEEEEESTGGGSSHHHHHHHHHHHHHHEE CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlgkakvtgvDiseemleaareraeeeglnvefvqgdaedlpfedgsfDlvvssgalhhlsdedlekalkeiarvLk 94 
                      vLd+G+GtG +++++a+  ++++v+g+D+s+ +  ++        +n++f + d+e+    d++fD+++++ a++  s +d++++l+++ + L+
       EEA19693.1  89 VLDFGTGTGSWAIDFADLHPDSHVVGIDLSPIQPSNT-------PPNCRFFVDDIESPWTFDSKFDFIHAR-AMS-GSIRDWDTLLQQALENLN 173
                      9*****************889**********987754.......3577*******99777778*******6.544.3556999******99999 PP

                      EEE CS
  Methyltransf_25  95 pgG 97 
                      ++G
       EEA19693.1 174 EDG 176
                      888 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 3.5
                      HHHHHHHHHHHHTTTTEEEEESBCCGBSSST CS
  Methyltransf_25  32 emleaareraeeeglnvefvqgdaedlpfed 62 
                      ++l++a er+ +   +ve +++ +e++ f d
       EEA19693.1 205 RQLNEASERVGQPMNSVETLKARLEKCGFVD 235
                      5677888888766558888888888877655 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.0   0.0     1e-09   1.4e-06       1      99 []      90     178 ..      90     178 .. 0.91

  Alignments for each domain:
  == domain 1  score: 29.0 bits;  conditional E-value: 1e-09
  Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvelealdlldldgg.ssfDlvvasnvlhhlkdirevldnirklL 93 
                      L++G+GtGs +  +++ +pd++++g+D+sp +             n   n++++++d+++     s+fD ++a      ++d++ +l+++ + L
       EEA19693.1  90 LDFGTGTGSWAIDFADLHPDSHVVGIDLSPIQP-----------SNTPPNCRFFVDDIESPWTFdSKFDFIHARAMSGSIRDWDTLLQQALENL 172
                      8*****************************999...........4455688999888876666689**************************** PP

  Methyltransf_12  94 kpgGrl 99 
                      + +G++
       EEA19693.1 173 NEDGVI 178
                      ***986 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.3   0.0   6.5e-09     9e-06       1      94 [.      90     178 ..      90     180 .. 0.89
   2 ?    0.9   0.0      0.52   7.2e+02      20      59 ..     196     235 ..     183     241 .. 0.79

  Alignments for each domain:
  == domain 1  score: 26.3 bits;  conditional E-value: 6.5e-09
                      EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-EEEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHHHEEEEE CS
  Methyltransf_11   1 LdvGcGtGrlaealakrg..arvvgvDlskemlklakekaseeglkvefvvadaeklpfednsfDlvvssevlhhvedpekalkeiaRvLkpgG 92 
                      Ld+G+GtG+ a ++a+    ++vvg+Dls+ +       +++++ +++f v d+e+    d++fD++ ++ +   + d++ +l+++   L  +G
       EEA19693.1  90 LDFGTGTGSWAIDFADLHpdSHVVGIDLSPIQP------SNTPP-NCRFFVDDIESPWTFDSKFDFIHARAMSGSIRDWDTLLQQALENLNEDG 176
                      8**************88899**********998......33344.499*******9645578*************************9999999 PP

                      EE CS
  Methyltransf_11  93 ll 94 
                      ++
       EEA19693.1 177 VI 178
                      86 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.52
                      EEEEEES-HHHHHHHHHHCCHHT-EEEETTEECCCTSS-T CS
  Methyltransf_11  20 rvvgvDlskemlklakekaseeglkvefvvadaeklpfed 59 
                      r+ ++ +++++l+ a+e++ ++ ++ve ++a++ek  f d
       EEA19693.1 196 RTEAIRTWQRQLNEASERVGQPMNSVETLKARLEKCGFVD 235
                      5667778889999999999999999999999999988766 PP

>> FtsJ  FtsJ-like methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.0   3.2e-07   0.00044      15      77 ..      79     143 ..      58     188 .. 0.80

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 3.2e-07
                 HHT-S-TT-EEEECT-TTSHHHHHHCCT.T.-SEEEEEESSSSHHH...TTEEEECS-CCCSSHHH CS
        FtsJ  15 kfklfkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpmapl...pgvttiqgditdpetie 77 
                 + +l +p ++v+D g ++G+w+   +   +++++vv++Dl p++p    p+++++  di +p t +
  EEA19693.1  79 RTRLPHPPRHVLDFGTGTGSWAIDFADL-HPDSHVVGIDLSPIQPSntpPNCRFFVDDIESPWTFD 143
                 3333345578***********9998888.567***********7777789*********9997766 PP

>> TagF_N  TagF N-terminal domain, Type VI secretion system-associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.9   0.1   6.3e-05     0.087       9      40 ..     145     176 ..     142     190 .. 0.84
   2 ?    1.1   0.0      0.28   3.8e+02      92     134 ..     188     230 ..     183     231 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 6.3e-05
                 -SS-EEES--HHHHHHHHHHHHHHHHHHHHHH CS
      TagF_N   9 kgDFvkrrlprallaawdeWlqaglaalreel 40 
                 k DF+++r+ +  ++ wd  lq++l++l+e+ 
  EEA19693.1 145 KFDFIHARAMSGSIRDWDTLLQQALENLNEDG 176
                 67*************************99876 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.28
                 -TTB-HHHHHTS-SHHHHHHHHHHHHTTSTT--HHHHHHHHHT CS
      TagF_N  92 eaeeasaallaaaeewfealealllsaldeelsvealeaalaa 134
                 ++++ + +  +a ++w ++l+++  ++ +   sve+l+a+l++
  EEA19693.1 188 KSDDGTLERTEAIRTWQRQLNEASERVGQPMNSVETLKARLEK 230
                 555666678889999***********9999999***9999975 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   1.6e-05     0.022      28      64 ..      83     118 ..      59     180 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 1.6e-05
                 HCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESB CS
         MTS  28 pkelsgkvlDlGcGaGvlgaalakespeaevtlvdvd 64 
                 p+   ++vlD+G+G+G  ++ +a+ +p+ +v+ +d +
  EEA19693.1  83 PH-PPRHVLDFGTGTGSWAIDFADLHPDSHVVGIDLS 118
                 33.5568*********************999888865 PP

>> Methyltransf_4  Putative methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   5.1e-05     0.071       5      34 ..      89     118 ..      86     122 .. 0.92
   2 ?   -1.0   0.1      0.77   1.1e+03      98     116 ..     163     181 ..     161     222 .. 0.78
   3 ?   -2.8   0.3       2.6   3.6e+03      83      91 ..     247     255 ..     246     256 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 5.1e-05
                     EEEET-TTSHHHHHHHHHSTTSEEEEEES- CS
  Methyltransf_4   5 vleiGcGkGeflvalAkknPdknflGiEir 34 
                     vl+ G+G G++ ++ A  +Pd  ++Gi+++
      EEA19693.1  89 VLDFGTGTGSWAIDFADLHPDSHVVGIDLS 118
                     79*************************975 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.77
                     HHHHHHHHHEEEEEEEEEE CS
  Methyltransf_4  98 ellkelarvLkkgGvlela 116
                     +ll+++ + L++ Gv+el+
      EEA19693.1 163 TLLQQALENLNEDGVIELQ 181
                     6889999999999999887 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 2.6
                     ---SGGGGG CS
  Methyltransf_4  83 PwfKkrhhK 91 
                     Pw+K r+ K
      EEA19693.1 247 PWPKDRRLK 255
                     *****9876 PP

>> Tektin  Tektin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.5   7.9e-05      0.11      42      86 ..     187     231 ..     157     232 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 7.9e-05
      Tektin  42 adsnkrLeeRiediefwkeeLekeleelkeeieaLeeekrrleka 86 
                 ++s++   eR+e i+ w+++L+++ e++ + ++++e+ k rlek+
  EEA19693.1 187 YKSDDGTLERTEAIRTWQRQLNEASERVGQPMNSVETLKARLEKC 231
                 555666679**********************************96 PP

>> PrmA  Ribosomal protein L11 methyltransferase (PrmA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00011      0.15     161     196 ..      85     121 ..      75     180 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00011
        PrmA 161 egeevlDvGtGSGiLaiaaakLga.kkvvavDiDevA 196
                 + ++vlD+GtG+G  ai  a L   ++vv++D+ ++ 
  EEA19693.1  85 PPRHVLDFGTGTGSWAIDFADLHPdSHVVGIDLSPIQ 121
                 5679**************9999862689*****9975 PP

>> Ubie_methyltran  ubiE/COQ5 methyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0   0.00033      0.45      38      81 ..      76     118 ..      62     123 .. 0.79
   2 ?   -2.0   0.0       1.3   1.8e+03     201     217 ..     221     237 ..     214     244 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00033
                      HHHHH--S--TTEEEEES-TT-HHHHHHHHHHHHHHEEEEEES- CS
  Ubie_methyltran  38 fveklvavkrgakvlDvagGtgDlafklsdsvgekgkvvvlDin 81 
                       ++++  ++++++vlD  +Gtg +a++++d  +   +vv++D++
       EEA19693.1  76 HLHRTRLPHPPRHVLDFGTGTGSWAIDFADL-HPDSHVVGIDLS 118
                      556667788899****************996.556678888887 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.3
                      HHHHHHHHHHTTEEEEE CS
  Ubie_methyltran 201 qetlkeliedaGfksve 217
                       etlk+ +e+ Gf  v+
       EEA19693.1 221 VETLKARLEKCGFVDVR 237
                      68999999999999987 PP

>> TrmB  Sugar-specific transcriptional regulator TrmB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.43   5.9e+02      40      56 ..     166     182 ..     163     188 .. 0.80
   2 ?    8.2   0.0    0.0016       2.2      26      60 ..     208     242 ..     204     246 .. 0.88

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.43
                 HHHHHHHHHCTSEEEES CS
        TrmB  40 YevLrsLedkGlVerek 56 
                 +++L++L + G++e ++
  EEA19693.1 166 QQALENLNEDGVIELQE 182
                 67899999999999876 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.0016
                 CHHCCCTTSSCHCHHHHHHHHHHCTSEEEESSTTT CS
        TrmB  26 deiaeelgvprskvYevLrsLedkGlVerekgrpk 60 
                 +e +e++g p ++v     +Le++G+V++++  +k
  EEA19693.1 208 NEASERVGQPMNSVETLKARLEKCGFVDVRDDAYK 242
                 57799***********************9987665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (323 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       722  (0.04027); expected 358.6 (0.02)
Passed bias filter:                      668  (0.0372581); expected 358.6 (0.02)
Passed Vit filter:                        70  (0.00390429); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 2145.54
//
Query:       EEA19694.1  [L=419]
Description: alpha methylacyl-CoA racemase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.6e-51  173.8   0.0    7.5e-51  173.4   0.0    1.2  1  CoA_transf_3  CoA-transferase family III


Domain annotation for each model (and alignments):
>> CoA_transf_3  CoA-transferase family III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  173.4   0.0   4.2e-55   7.5e-51       1     323 [.      12     347 ..      12     391 .. 0.81

  Alignments for each domain:
  == domain 1  score: 173.4 bits;  conditional E-value: 4.2e-55
  CoA_transf_3   1 LaGvrVldlsqvlaGplatslLAdlGAeVIkvEppk.kgDpaRkvgpsee.kgesayflavnrnKrsvalDlkseegrellkrLvakADVvieNfrp 95 
                   LaG++Vl+l+ + ++p+ +++LAdlG +V++++pp  k  p+ + +     ++++ +  ++ r K s+ +D++ ++ r++++rL++ ADV+i+++r+
    EEA19694.1  12 LAGLKVLELAGIAMAPFTGMVLADLGCDVVRIDPPAkKTTPTKNNNT--TpQKQKRWIDSLCRHKSSIIVDFEFAASRQAFLRLLDAADVLIDSYRA 106
                   89*********************************533344444333..3579******************************************** PP

  CoA_transf_3  96 gvlerl.glgyeelrainPrLiyasvsgyGqsG.pkakrpgyDlvaqaasGlmsltge..pdgp...............PvkvgvplgDivtgll.a 172
                   g  er+ g+++eel ++ PrLiya+v+gy +    +a+  g+  ++ a+sG +    +  p  p                  + ++l+D+ +g + +
    EEA19694.1 107 GLFERMiGMSAEELCRRYPRLIYARVTGYSRYDkRYANALGHENNFVAVSGALPALQHasP--PssttatpssnedstiLRPTVNYLADFGGGSMaC 201
                   ***9966************************76599**************98877433122..2234556566666554344556789997775515 PP

  CoA_transf_3 173 availaallarertGkGqvidvslleaalallapqlley.latgevperqgnrdpaaapygvyrtkdg.wvaiaaatdkqwaalckalgrpelaedp 267
                   +v+ilaa+++r++ GkGq +d+s  +++  l  + l+    ++ ++p        +a+ +++yrt+dg +++++  +d+ +++l++ lg +      
    EEA19694.1 202 VVGILAAVIHRNASGKGQIVDASVQQGTRYLATFPLQRRnGQPDNEPP--LTGVNDAPWSDAYRTADGkYMMVSSIEDALYERLIRGLGLDP----A 292
                   678*******************98888877777777665444444444..4444455779*****************************985....3 PP

  CoA_transf_3 268 rfatnasrlenraeldaelaewlaertaaewlellaaagvpaapvntleevlddpq 323
                   +  ++++r +n   +++ la+++ ++++ +w  ++++ + +++pv ++++  ++++
    EEA19694.1 293 MVPDRTDR-RNWPGIRKVLAARFGSQSQGHWRSVFDRLQACVSPVLDVDDDEEEEE 347
                   66777776.889************************************98655544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (419 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       530  (0.029561); expected 358.6 (0.02)
Passed bias filter:                      498  (0.0277762); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 2821.05
//
Query:       EEA19695.1  [L=610]
Description: hypothetical protein PMAA_004740 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
  ------ inclusion threshold ------
      0.017   15.0   0.0      0.074   13.0   0.0    2.2  1  F-box-like  F-box-like


Domain annotation for each model (and alignments):
>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   4.1e-06     0.074       4      46 ..      15      55 ..      12      57 .. 0.91

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 4.1e-06
  F-box-like  4 LPdEiLlqIFsyLppsdLlrlalVCrrWrrvaldtplLWrrlv 46
                LP+E+L +I + L p d ++la ++r  ++     p+L++++ 
  EEA19695.1 15 LPHELLDKIVQGLFPGDVVSLAKTSRLMHQRM--IPFLYTQVI 55
                9************999************9998..789999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (610 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       291  (0.0162307); expected 358.6 (0.02)
Passed bias filter:                      283  (0.0157845); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.66u 0.28s 00:00:00.94 Elapsed: 00:00:00.51
# Mc/sec: 3620.13
//
Query:       EEA19696.1  [L=583]
Description: sugar transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   9.2e-122  407.1  20.9   1.4e-121  406.5  20.9    1.3  1  Sugar_tr  Sugar (and other) transporter
    2.3e-30  105.7  62.8    3.7e-25   88.6  35.8    2.2  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  406.5  20.9  1.6e-125  1.4e-121       2     451 ..      44     536 ..      43     537 .. 0.95

  Alignments for each domain:
  == domain 1  score: 406.5 bits;  conditional E-value: 1.6e-125
                 HHHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTS CS
    Sugar_tr   2 alvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgkn 100
                 +++++lg +++gYd gv+g++l + +f ++f    s++        +g++vs++ +Ga +G+lf g+l+d ++Rk+s+++a+++f  g+ lq  a+   
  EEA19696.1  44 CVFVSLGCMMYGYDQGVMGPILVMENFMNHFPGLMSSN--I-----QGWLVSALELGAWAGALFNGYLSDAISRKYSMMFAVLVFTLGTGLQSGAQ--- 132
                 899999********************999999988886..4.....49************************************************... PP

                 S-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-................................T CS
    Sugar_tr 101 svevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsn................................a 167
                 s   ++vgR++ G+g+G++s+++P+y++EiAp++lRg lvsl+ql+it+G  +a+++++g++++++                                +
  EEA19696.1 133 SPAYFFVGRIIGGFGIGMFSMVIPLYQAEIAPPELRGSLVSLQQLSITIGTTIAFWLDFGFSYIGSthcnpegiadpydskgnynydqnsghtctgqkT 231
                 9*************************************************************************************************9 PP

                 THHHHHHHCCHHHHHHHHHHGGGS---HHHHHHTT-HHHHHHHHHHHHHC....HHHHHHHHHHHHHHHHHHH..............HTTHHHHSH... CS
    Sugar_tr 168 dgwrillglqlvpallllilllflPESPrylvekgkeeeakevlaklrge....edadrelaeekdsleaeqeee.........kaswkellssktvrq 253
                 + wr++l+lql+pa +l+++l+f+P SPr+l+ k +e+ea+  l++lr      ++ + e+ e+k++    +++e          a wk l+   ++ +
  EEA19696.1 232 VSWRVPLALQLIPAWVLFFGLFFFPFSPRWLMLKHREDEARSALSRLRRLdpqdPLLTAEFLEIKAAVMFDEQTEaelvgsggiLAPWKALFAP-NMIK 329
                 **********************************************8888555666777888888777777666689*****999********9.99** PP

                 HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH...HHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH.....HHHHTTSS. CS
    Sugar_tr 254 rlligvvlqifqqltGinaimyysptifenlglsks...llvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilg...ivalllvaks. 345
                 r+++g ++++fqq+tGina++yy+p+if++ g+s +   ll+t+++g++++++t+ ++f+ d+fGR+t+l++Ga+gm+ic vi++   +v  ++ +k+ 
  EEA19696.1 330 RVFLGSGMMVFQQFTGINAVLYYAPQIFKSFGFSSTttdLLATGVTGILQIIFTLPSVFFLDKFGRKTFLIIGAIGMFICHVIVAsveGVYKPQWDKNe 428
                 **********************************99999**********************************************99877777777778 PP

                 ......CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--ST CS
    Sugar_tr 346 ...kaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetk 441
                       + vaivfi lf++ fa +wgpv wvl++E+fp s+Rs + ai++ +nw++nf+i+l+++ ++++++ ++++++fa++ + + +f++ f+petk
  EEA19696.1 429 hlaVTQGWVAIVFIWLFAVNFAYSWGPVAWVLAQEIFPASMRSRGVAIVASTNWMFNFIIGLTTKDMLDSMQ-YGTYIFFAIFSLGGGFFIWQFFPETK 526
                 99878899****************************************************************.************************** PP

                 T--CCCCGGG CS
    Sugar_tr 442 grtleeieel 451
                  +tlee++  
  EEA19696.1 527 DKTLEELDVF 536
                 ******9876 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.6  35.8   4.1e-29   3.7e-25       3     347 ..      49     484 ..      40     490 .. 0.80
   2 !   31.4  19.1     1e-11   9.2e-08       4     176 ..     338     526 ..     336     535 .. 0.75

  Alignments for each domain:
  == domain 1  score: 88.6 bits;  conditional E-value: 4.1e-29
       MFS_1   3 laaflsalarsilgpalplalaedlg......ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.sslw.lllvlrv 93 
                 l+ ++++++ ++ gp+l    +e++       +s   +g+l+++  lga++++l+ G+lsd ++r+  +++++l+f lg + l  + ++++ +++v+r+
  EEA19696.1  49 LGCMMYGYDQGVMGPILV---MENFMnhfpglMSSNIQGWLVSALELGAWAGALFNGYLSDAISRKYSMMFAVLVFTLG-TGLQ-SgAQSPaYFFVGRI 142
                 444555555566666665...455556666999999***************************9999************.6666.4499999******* PP

       MFS_1  94 lqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg...................................Wravfyil 157
                 + G+g g++  ++  + a+++p+e rg+ ++l ++++ +G+ ++  l   ++  ++                                   Wr++  + 
  EEA19696.1 143 IGGFGIGMFSMVIPLYQAEIAPPELRGSLVSLQQLSITIGTTIAFWLDFGFSYIGSthcnpegiadpydskgnynydqnsghtctgqktvsWRVPLALQ 241
                 ***************************************************95555******************************************* PP

       MFS_1 158 aivsllafvlfllllpeepperkrkspkeee....................................kgtgpaplvp......awkallkdpvlw.... 210
                  i + ++f  +l+++p +p+    k  ++e                                     +      lv       +wkal++++ +     
  EEA19696.1 242 LIPAWVLFF-GLFFFPFSPRWLMLKHREDEArsalsrlrrldpqdplltaefleikaavmfdeqteaE------LVGsggilaPWKALFAPNMIKrvfl 333
                 ******966.3477755555555554444445555566666799999999998899999995444443......3334666669********5532112 PP

       MFS_1 211 illialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavt............ 297
                    ++++  f+g++++l++ p +  + +g+s+  + +l+ ++++++ +i+ l + +++d++gr+++l+++ ++++++ +++a +               
  EEA19696.1 334 GSGMMVFQQFTGINAVLYYAPQI-FKSFGFSSTTTDLLATGVTGILQIIFTLPSVFFLDKFGRKTFLIIGAIGMFICHVIVASVEGVykpqwdknehla 431
                 223333333667777*******7.*******4466666778888888888*******************************9999999*****999888 PP

       MFS_1 298 ssavllllvlvl.iGf.glgfvfpsllalasdlappeeagtasglfn.tagsl 347
                  ++ ++++v++  + + ++    p +++la++ +p++++ + ++++  t + +
  EEA19696.1 432 VTQGWVAIVFIWlFAVnFAYSWGPVAWVLAQEIFPASMRSRGVAIVAsTNWMF 484
                 6666666644444444333334999***************9999988455544 PP

  == domain 2  score: 31.4 bits;  conditional E-value: 1e-11
       MFS_1   4 aaflsalarsilgpalplalaedlgispseigllltl.yalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllf.....ass........... 84 
                 ++f  ++++++++  +p  + +++g+s ++  ll+t+  ++++++++lp  ++ d+fGr+ +l++g+++++++ ++++++     + +           
  EEA19696.1 338 MVFQQFTGINAVLYYAP-QIFKSFGFSSTTTDLLATGvTGILQIIFTLPSVFFLDKFGRKTFLIIGAIGMFIChVIVASVegvykP-Qwdknehlavtq 434
                 56778888888888999.799************98886889********************************6666664433340.133344444444 PP

       MFS_1  85 .lw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGa.ilgpllggllasslgWravfyilaivsllafvlfllllpeep 176
                  +  ++++  +   +++ +  p++ +l+ ++fp + r+r+++++++++ +   i+g     +l  s    ++++++ai+sl ++ +++ ++pe++
  EEA19696.1 435 gWVaIVFIWLFAVNFAY-SWGPVAWVLAQEIFPASMRSRGVAIVASTNWMFNfIIGLTTKDMLD-SMQ-YGTYIFFAIFSLGGGFFIWQFFPETK 526
                 46656666666666665.44577889********************999999466655555555.554.58999999999999887555555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (583 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       580  (0.0323498); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.24s 00:00:00.83 Elapsed: 00:00:00.41
# Mc/sec: 4311.93
//
Query:       EEA19697.1  [L=456]
Description: vacuolar H+\/Ca2+ exchanger [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.3e-30  105.0  21.1    3.8e-15   56.2   5.2    2.2  2  Na_Ca_ex      Sodium/calcium exchanger protein


Domain annotation for each model (and alignments):
>> Na_Ca_ex  Sodium/calcium exchanger protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.9   8.0   5.1e-19   9.2e-15       3     150 ..     109     276 ..     107     277 .. 0.92
   2 !   56.2   5.2   2.1e-19   3.8e-15       3     150 ..     312     453 ..     310     454 .. 0.89

  Alignments for each domain:
  == domain 1  score: 54.9 bits;  conditional E-value: 5.1e-19
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCTHHHHHHHHHHHHHHHHHHHHHHHHHHTTT....HHHHHHHHHHHHHHHHHTHHHHHHHHHHBTTSSC CS
    Na_Ca_ex   3 fvlfilslllisvladflvssaeeiakslgisgsvlGltllAlgnslpElissiiaaltge....vdlaignvlGsnifnlllviGlialigslkvdse 97 
                 +++f+l +++i+++a++l  +  e+a   +  ++v+G++l +  +s+ E+i+ +i ++t++    +++  +++lGs+++nlll++Gl++++g+  +++e
  EEA19697.1 109 VWVFALNYIAIIPTANLLGFAGGELA---RKLPRVYGVLLETSLTSAVEIILFMILIKTDNsdelINVIQAAILGSILANLLLCLGLCFFFGG-LRRNE 203
                 799***********************...89999*************************88778999999***********************.77777 PP

                 ECCHHHHHHHHHHHHHHHHHHHTCHHHHH.....................HTEEHHHHHHHHHHHHHHHHHHHH CS
    Na_Ca_ex  98 slkldlgllllvallllllvlllllplfv.....................pgrltvleglvllllYalylvlsl 150
                 ++ l+  +  + + lll++ + ll+p ++                     ++++++ ++++ll +Y+++l+++l
  EEA19697.1 204 QI-LHEAVSEVGSGLLLVAGFGLLIPSAFhatlsgsvtdgtmtseelrdtTNKVSRATAVILLCAYFMFLWYNL 276
                 74.44458888888888889999999999999999***********************************9986 PP

  == domain 2  score: 56.2 bits;  conditional E-value: 2.1e-19
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCTHHHHHHHHHHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHHHTHHHHHHHHHHBTTSSCECCH CS
    Na_Ca_ex   3 fvlfilslllisvladflvssaeeiakslgisgsvlGltllAlgnslpElissiiaaltgevdlaignvlGsnifnlllviGlialigslkvdseslkl 101
                 ++++ +sl ++s++a flv+ + +i+   g+++ ++Gl+l++l+  + E++++i  a+ ++++ a+  +lG  i+  ll  +l++l+g+    +++++l
  EEA19697.1 312 LLAITASLTCVSLSAYFLVEKIPAIV-ERGVPDNFMGLILVPLVEKAAEHLTAIDEAWDNQINFALFHCLGPSIQTALLNAPLVVLVGW--GLGKEMDL 407
                 688999********************.58**********************************************************99..44455789 PP

                 HHHHHHHHHHHHHHHHHHTCHHHHHHTEEHHHHHHHHHHHHHHHHHHHH CS
    Na_Ca_ex 102 dlgllllvallllllvlllllplfvpgrltvleglvllllYalylvlsl 150
                 +++++++++l+l++lv+  +l    +g+ +++eg +++l+Y++++v  +
  EEA19697.1 408 NFEIFMVILLVLSILVVGNFLR---DGKSNYMEGGLCVLVYVIIAVTTW 453
                 9988777777776666665544...5******************99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (456 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       703  (0.0392102); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.48
# Mc/sec: 2867.05
//
Query:       EEA19698.1  [L=178]
Description: hypothetical protein PMAA_004770 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.093   12.1   2.2       0.71    9.2   0.1    2.1  2  DUF1616   Protein of unknown function (DUF1616)


Domain annotation for each model (and alignments):
>> DUF1616  Protein of unknown function (DUF1616)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.1   3.9e-05      0.71      81     121 ..       8      48 ..       1      69 [. 0.79
   2 ?    3.2   0.2    0.0027        48     225     261 ..     106     142 ..      79     147 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 3.9e-05
     DUF1616  81 irlepilvslslftlllalvAivrRsrlpeeerfsvplral 121
                 i +  ++vs  ++t+l ++ +++rR++  ee   +++ +++
  EEA19698.1   8 IIAIVVVVSALFVTILWTFSGYYRRTSAREEANVHISQEQY 48 
                 556678899999*******************9999976554 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.0027
     DUF1616 225 eeevevlerteldrrevtladnetweqelevepeatg 261
                 e ++++ e++ ld+ ++++a++e+ e++++++  ++ 
  EEA19698.1 106 EGTTNTNEKQSLDQGSANVAQQEKDESRVNYSTYEPA 142
                 455667799*****************99998877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (178 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       952  (0.0530983); expected 358.6 (0.02)
Passed bias filter:                      549  (0.0306208); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 1184.84
//
Query:       EEA19699.1  [L=295]
Description: hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      1e-24   87.6   0.0    1.7e-24   86.9   0.0    1.3  1  Abhydrolase_1    alpha/beta hydrolase fold
    1.5e-12   48.6   0.1    2.2e-12   48.0   0.1    1.2  1  Abhydrolase_6    Alpha/beta hydrolase family
    5.5e-07   29.1   0.0    0.00043   19.6   0.0    2.2  2  Hydrolase_4      Serine aminopeptidase, S33
  ------ inclusion threshold ------
      0.074   12.0   0.0       0.11   11.4   0.0    1.3  1  Chlorophyllase2  Chlorophyllase enzyme
        0.1   12.2   0.1       0.16   11.5   0.1    1.2  1  Peptidase_S15    X-Pro dipeptidyl-peptidase (S15 family)


Domain annotation for each model (and alignments):
>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.9   0.0   4.6e-28   1.7e-24       1     255 [.      33     277 ..      33     279 .. 0.85

  Alignments for each domain:
  == domain 1  score: 86.9 bits;  conditional E-value: 4.6e-28
                    SEEEEE-STTTCGGGGTTGHHHHHHHHTTSEEEEEEETTSTTSSSTTTGB.CHHSHHHHHHHHHHHHHHCTTSSEEEEEETHHHHHHHHHHHHHGG CS
  Abhydrolase_1   1 pvlvilhGlpgssdvwaerglapaLakdgfdvillDlrGvgySspapacinddygtasvaddldrildalgddkltlvGhSmGGmialayaaeype 96 
                    pvl++lhG+p ss+ +++  l+p La  +++vi++Dl+G+g+++ a        +++++a  +  ++d l + k+ +  +++G  +al++a++ pe
     EEA19699.1  33 PVLLLLHGFPSSSHQYRN--LIPLLAA-KYRVIAPDLPGFGFTEVAGV---YKHTFDNLALTILEFVDILSISKFSVYIFDYGAPTALTLALKRPE 122
                    79****************..******9.********************...5669999************************************** PP

                    GEEEEEEESECSSCCHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHHHHCCSCHHHHHHHHHHHHHHHCHHHCCHHHHHHHCHHHHHHHHHHHHHH CS
  Abhydrolase_1  97 rVkalvllgaidpaaslieaqrqqaksfpdffdgyaadcarnpagplladelaaleqrhrlvdalkfpdkskrfpssgsdnasslatgalksieqw 192
                      +a+++ ++         a +  +  f   ++ y a + + +a + +a  +a l+++     a k++ + +++p ++++++s++  +al+ + + 
     EEA19699.1 123 ALQAIITQNG--------NAYEDGLGDFWQPLREYWASGDKDNASTRAALAAAVLTYE-----ATKGQYTQGTLPGKTIAPESYTLDYALLQRPGN 205
                    **********........6666666666666777777777777777666666666666.....334577778888888888888888888888888 PP

                    HHCCHHHHHHHHHC..........THHHHSEEEEEEETTCSSSCHHHHHHHHHCHTSEEEEEEETCSSSHHHH CS
  Abhydrolase_1 193 pttdsaklllrlre..........lknvlaptlvisgtsDplvppkaledlaqllpkkrlvvisdagHlafle 255
                    ++ + + +++ +++          +++  +p l ++g +Dp++     e ++++lpk  +v++ dagH+a  +
     EEA19699.1 206 DNVQLDLFWDYQNNvknyprfqeyFRKSQVPLLAVWGKNDPIFIAPGAEAFKRDLPK-AEVHLLDAGHFAAET 277
                    888888888777777777777777667777***************************.***********9876 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.0   0.1   6.2e-16   2.2e-12       1     217 [.      35     282 ..      35     285 .. 0.58

  Alignments for each domain:
  == domain 1  score: 48.0 bits;  conditional E-value: 6.2e-16
                    EEEE--GC.....GCHHHHHHHHCCTCEEEEE--TTSTS-GGCS...--HHH.CHHHHHHHCCTT..TTSEEEEEETCHHHHHHHHHHCC...... CS
  Abhydrolase_6   1 vlllHGagssassWlvapLaallaagvhvlapDlpGhGrsdppp...ldled.ladlaalldelaagggpvvlvGHSlGGalalaaapla...... 86 
                    +lllHG++ss+++++  +L +llaa ++v+apDlpG+G+++ +    +++++ ++++++++d l  +  ++ +   ++G+  al    la      
     EEA19699.1  35 LLLLHGFPSSSHQYR--NLIPLLAAKYRVIAPDLPGFGFTEVAGvykHTFDNlALTILEFVDIL--SISKFSVYIFDYGAPTALT---LAlkrpea 123
                    79*******999998..*********************66555566677766334447777777..69999********987777...66555565 PP

                    ..EE.EEES-..----TTTS----TTHHHHHH..........TT-C..CCCHCCH.........S-HSCCCCHHHCCCCHCHCCCGHH.......H CS
  Abhydrolase_6  87 lvvg.vlldppptalpagllaaalelllalla..........llrl..lawlsre.........plprlfladedadaawrarlarla.......a 153
                    l  + +  ++   a+ +g l +++++l+ ++a          +  +  +a l++e              + +++ a ++++  +a l+       +
     EEA19699.1 124 L-QAiITQNG--NAYEDG-LGDFWQPLREYWAsgdkdnastrA--AlaAAVLTYEatkgqytqgT----LPGKTIAPESYTLDYALLQrpgndnvQ 209
                    3.22377777..333333.444444444333324344433331..02223332223335544442....222222225555555555533334443 PP

                    HCCHHC.HTTCCHHTT-TTGC.......EEEC.TT-C.HHHHCHHCCCHSTTEEETCE...SSS-HHHHSHHHH CS
  Abhydrolase_6 154 llaglg.llpaaawadlpvpl.......lvlg.geDp.lvprllerllaqagarlpvvlpgaGHlphleepdev 217
                    l+ +++ ++++ ++++  + +       l ++ ++Dp  +++ +e++ + +  + +v l +aGH+  + e +e+
     EEA19699.1 210 LDLFWDyQNNVKNYPRFQEYFrksqvplLAVWgKNDPiFIAPGAEAFKR-DLPKAEVHLLDAGHFAAETETEEI 282
                    3333333333444444444444444443555548888*77877899999.55555566899***9988666666 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.0   1.2e-07   0.00043       5     105 ..      33     128 ..      29     141 .. 0.84
   2 !    7.4   0.0   0.00065       2.3     184     224 ..     227     267 ..     207     279 .. 0.83

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 1.2e-07
  Hydrolase_4   5 avvvlvHGlaehsgryaelaeaLaaqGfavyalDhrGhGrsegkrghvpsfddyvdDlaafvekvkeehpelplfllGhSmGGliallyllrypdkva 102
                   v++l+HG+ ++s +y +l+  Laa  + v+a D  G+G +e + ++ + fd +   + +fv+ +      +++ ++    G+ +al+++l++p+ ++
   EEA19699.1  33 PVLLLLHGFPSSSHQYRNLIPLLAA-KYRVIAPDLPGFGFTEVAGVYKHTFDNLALTILEFVDILS----ISKFSVYIFDYGAPTALTLALKRPEALQ 125
                  5899****************98876.6***************99999999*999999999999888....4455555556778888888888888888 PP

  Hydrolase_4 103 gli 105
                  ++i
   EEA19699.1 126 AII 128
                  877 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.00065
  Hydrolase_4 184 eeraakitlPllllhGeaDkvvdpeasrelyerlgskdktl 224
                  +e   k ++Pll + G++D++    +++++ + l++++++l
   EEA19699.1 227 QEYFRKSQVPLLAVWGKNDPIFIAPGAEAFKRDLPKAEVHL 267
                  55566778**********************99999765554 PP

>> Chlorophyllase2  Chlorophyllase enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   2.9e-05      0.11      17      55 ..      32      69 ..      22     128 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 2.9e-05
  Chlorophyllase2 17 YpvllflhGylllnslYsqlLkhiashgfivvapqlykv 55
                      pvll+lhG+   ++ Y++l+  +a  ++ v+ap l  +
       EEA19699.1 32 APVLLLLHGFPSSSHQYRNLIPLLAA-KYRVIAPDLPGF 69
                     59********************9996.899***987654 PP

>> Peptidase_S15  X-Pro dipeptidyl-peptidase (S15 family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.1   4.5e-05      0.16     110     250 ..     108     256 ..     104     273 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 4.5e-05
                    HHHHHHHHHCTT--TTEEEEEEECE-S-TCCCCSECTTEEBCCHHHHHHHHHCCCCHHTSSS-STTHHHHHHHHHHCHCCCCCCTTHHH......T CS
  Peptidase_S15 110 YlGttqllaaatgvpalkaivpeaaisdlyddyyregGlvrapgglswedldllaealtsrradegdalkaaaryeaasdellaeldrq......t 199
                    Y++ t+l +a ++++al+ai+ + +  + y+      G +++p   +w++ d  ++ + +  a++  +++a +   +++  + + ++++       
     EEA19699.1 108 YGAPTALTLALKRPEALQAIITQNG--NAYE---DGLGDFWQPLREYWASGDKDNASTRAALAAAVLTYEATKGQYTQGTLPGKTIAPEsytldyA 198
                    9999*******************99..4555...45688999999999666666666666666666666666654555555555555554333322 PP

                    HHHHCCCC--SSSHHHHTT-HHHHH.......CT--S-EEEEEECCSSTTCCHHHHHH CS
  Peptidase_S15 200 pveselletgdydafWkdrnlseda.......dkvkapvllvgGwnDwnvkngaikly 250
                     + +   +  + d fW+ +n  +++       +k ++p+l v G nD +++    +++
     EEA19699.1 199 LLQRPGNDNVQLDLFWDYQNNVKNYprfqeyfRKSQVPLLAVWGKNDPIFIAPGAEAF 256
                    333444556667779999888886666677779**************88885544444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (295 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       298  (0.0166211); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 1957.13
//
Query:       EEA19700.1  [L=462]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.7e-11   43.1   0.0    3.9e-11   42.5   0.0    1.3  1  Glyco_hydro_30   Glycosyl hydrolase family 30 TIM-barrel doma
      3e-09   36.5   0.1    4.4e-09   36.0   0.1    1.4  1  Glyco_hydro_59   Glycosyl hydrolase family 59
    6.4e-08   32.7   0.6    1.8e-07   31.2   0.6    1.9  1  Glyco_hydro_30C  Glycosyl hydrolase family 30 beta sandwich d
     0.0032   17.1   2.1      0.013   15.1   0.0    2.6  3  Glyco_hydr_30_2  O-Glycosyl hydrolase family 30
  ------ inclusion threshold ------
        2.1    9.2   6.2        6.2    7.7   0.1    3.4  3  Big_7            Bacterial Ig domain


Domain annotation for each model (and alignments):
>> Glyco_hydro_30  Glycosyl hydrolase family 30 TIM-barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.5   0.0   1.1e-14   3.9e-11      81     180 ..     118     218 ..      50     237 .. 0.85

  Alignments for each domain:
  == domain 1  score: 42.5 bits;  conditional E-value: 1.1e-14
                     HHHHHHHHHH-SS-EEEEEES---GGGBTTSSSSSS-BBSS-TTSH....HHHHHHHHHHHHHHHHHHTT--ESEEESSSSGGGGGSTT-SSS-- CS
  Glyco_hydro_30  81 ipyikraqkynqdlkllaapwaapgwlkttkavkGkGalkGkagdi....yhkayakyfvkfleeyaksklsfwglsteneptaGsdkktklqsl 171
                       + k+a+kyn++l ++a  w+apg +kt ++ +  G + G  g +    + +aya y+v++++ y+ +++ +  l + nep       + ++s 
      EEA19700.1 118 FNLTKTALKYNPELYVYANAWSAPGCMKTVGTENDGGQICGVRGTNcthdWRQAYADYLVQYVKFYKAEGIDISLLGAWNEPDFNPVTYESMESD 212
                     567899*************************9999999887665432222789********************************999999**99 PP

                     B--HHHHHH CS
  Glyco_hydro_30 172 gftaetqrd 180
                     gf a+   d
      EEA19700.1 213 GFQAK---D 218
                     99874...4 PP

>> Glyco_hydro_59  Glycosyl hydrolase family 59
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.0   0.1   1.2e-12   4.4e-09      22     154 ..      62     210 ..      59     344 .. 0.85

  Alignments for each domain:
  == domain 1  score: 36.0 bits;  conditional E-value: 1.2e-12
  Glyco_hydro_59  22 eqrseiLdyLFkpkfgaslqilkveiGgdansts.Gtepshkrseeela.dverGyefwlakeAkkrnpdikldileWgaPgwlk.......... 104
                     e+++e+ ++LF+++ g  l+i++ +iG+   st   t p++   + +++ d +   +f l k A k np++ +++ +W+aPg +k          
      EEA19700.1  62 ENQEEVTKILFDENIGG-LSIVRNDIGSSLGSTIlPTCPATPAGPFNYHwDGSDSCQFNLTKTALKYNPELYVYANAWSAPGCMKtvgtendggq 155
                     67889**********96.***********99985357777777666653267899**************************************** PP

  Glyco_hydro_59 105 .......ksaekasektaeylkswlkgakktygldidyiaglrnekeydkdyvktlr 154
                            + +++++++ a+yl++++k   k  g+di+ + g++ne + +   ++++ 
      EEA19700.1 156 icgvrgtNCTHDWRQAYADYLVQYVKFY-KAEGIDISLL-GAWNEPDFNPVTYESME 210
                     ****99878899*************876.678*******.*9999987765555543 PP

>> Glyco_hydro_30C  Glycosyl hydrolase family 30 beta sandwich domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.2   0.6   5.1e-11   1.8e-07       1      63 [.     371     457 ..     371     459 .. 0.80

  Alignments for each domain:
  == domain 1  score: 31.2 bits;  conditional E-value: 5.1e-11
  Glyco_hydro_30C   1 GavRigtsgspsvssnvetvAFlnpDGsivvvilNrsessvtitvs...............dssk............skgslsvparSiv 63 
                      G+vRig+++s    +nv ++A+ n++G++ + ++N +    ++t++               d+s+            s+ + +vp+r+++
       EEA19700.1 371 GSVRIGATSSV---ENVYVSAYENKNGTVSIPVINAAHFPYEVTIDlkglkvgkrvstfltDNSHnvtlmdqsalhgSVLQATVPPRAVQ 457
                      9******9984...57*******************9888777777777999999888888833335555555557777788888999987 PP

>> Glyco_hydr_30_2  O-Glycosyl hydrolase family 30
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0      0.24   8.7e+02       3      49 ..      26      75 ..      24      87 .. 0.79
   2 !   15.1   0.0   3.6e-06     0.013     135     240 ..     151     258 ..     107     305 .. 0.68
   3 ?   -0.7   0.9      0.23   8.4e+02     328     354 ..     309     336 ..     299     342 .. 0.80

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.24
                     EEEEEEEEEEEE--EEEEE-T..TTHHHH.HHHS-HHHHHHHHHHHH--- CS
  Glyco_hydr_30_2  3 kisidlqeeyqtidsfgasDa..Wsakfv.GkkapeekknkiadlLfske 49
                     +i++++ ++yq++   g s a  W+++         e ++++  +Lf ++
       EEA19700.1 26 NIQVNAFQKYQEMIGGGCSGAfgWACQQFpTTGLTPENQEEVTKILFDEN 75
                     7999999******9999998766999755144466677888888888765 PP

  == domain 2  score: 15.1 bits;  conditional E-value: 3.6e-06
                      SSSSB-S-SSS-SS-TT-HHHHHHHHHHHHHHHHCTT--EEEEE--S-T-GGG--..SS-B----HHHHHHH.HHHHHHHHHHHT-S-EEEEEE CS
  Glyco_hydr_30_2 135 ngkavstkekelnlkadkiddfadflvkvadkfrkegvkfdylsPvnePqWdwge.gsqeGtpatnediaal.vrkLseklsekklktkivlge 226
                      n  +   + + +n  +d  +++ad+lv+ ++ ++ eg+++  l   neP ++  +  s e    + +d  ++   ++++++ + +++   ++g 
       EEA19700.1 151 NDGGQICGVRGTNCTHDWRQAYADYLVQYVKFYKAEGIDISLLGAWNEPDFNPVTyESMESDGFQAKDFLEIlYPTVKKAFPNLDISCCDATGA 244
                      444444455568999999*******************************998665456666666555554441456666666666666666666 PP

                      ESSGGGGS---.-T CS
  Glyco_hydr_30_2 227 agqldyLykkkese 240
                        + + Ly+ ++ +
       EEA19700.1 245 RQERNILYEVQQAG 258
                      67777777777644 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 0.23
                      HHHHHHHHHHHHHHHTS--SEE.EEEES CS
  Glyco_hydr_30_2 328 dlgLyvakvihnDLtlanasaW.qWWla 354
                        gL  a  +hn +t++++s + +WW a
       EEA19700.1 309 AEGLQWALYMHNAFTNSDTSGYnHWWCA 336
                      4567777778**********98579976 PP

>> Big_7  Bacterial Ig domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       2.8     1e+04      49      59 ..     103     113 ..      87     124 .. 0.77
   2 ?    3.1   0.5     0.046   1.6e+02      47      64 ..     293     311 ..     283     334 .. 0.88
   3 ?    7.7   0.1    0.0017       6.2      25      69 ..     377     435 ..     363     436 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 2.8
                 SSSEEEEEE-- CS
       Big_7  49 sapysltwttt 59 
                 ++p+++ w+ +
  EEA19700.1 103 AGPFNYHWDGS 113
                 58999999865 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.046
                 E-SSSEEEEEE--....SE CS
       Big_7  47 dtsapysltwttta.ltag 64 
                 d s+p+++tw+ +  l++g
  EEA19700.1 293 DGSGPWNTTWDVSGqLAEG 311
                 889********97766655 PP

  == domain 3  score: 7.7 bits;  conditional E-value: 0.0017
                 EE-SS-EEEEEEEETTEE.......EEEE-SSSEEEEEE-..........-...SEEEEEE CS
       Big_7  25 AsddggvskVefyvdgtl.g.....lgtdtsapysltwtt..........taltagthtlt 69 
                 A+  ++v++V ++++ ++ g     + + +  py++t++           t lt+++h++t
  EEA19700.1 377 AT--SSVENVYVSAYENKnGtvsipVINAAHFPYEVTIDLkglkvgkrvsTFLTDNSHNVT 435
                 44..4599****9999997789989889999999999999999999998544999999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (462 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       358  (0.0199677); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 3311.56
//
Query:       EEA19701.1  [L=451]
Description: fungal specific transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.3e-09   37.5   1.7    3.1e-09   36.2   1.7    1.7  1  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2   1.7   1.8e-13   3.1e-09       1     190 [.      28     205 ..      28     234 .. 0.83

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 1.8e-13
  Fungal_trans   1 ldrffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsL 97 
                   ld +f+ f+   pi+ +++fl+ +       +a + + l+ ++ ++ a + + +    + +++ +        l+a+ l   d    s+ l      
    EEA19701.1  28 LDKYFDLFNDANPIFSRENFLHRY------RKALCCQDLISTMTIITAKLIGFALEGPDLDARID------HLLSANHLE-LDIIGDSPTLDQMRKA 111
                   689*********************......88888888888888888888888888875666653......446777777.4555566669999999 PP

  Fungal_trans  98 lllelyektssdralherhhgvavrlarslgLhrnpsyvgkks.lwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddd 190
                    +l++ye+     ++ ++ +g   r+a+++g  + +      s +   +++e +++r lww+++ +D ++ l  G p+l++++ in++L  +++
    EEA19701.1 112 YILAFYEFHQFPGDQSWMRMGRLTRIAYRVGIDKLERLPTFYSdWAAISKAEMQEWRLLWWCIYKVDSYTNLAAGTPYLINKDFINTALLTSQS 205
                   9*******999999*****************8887777665555777777778889********************************877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (451 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       375  (0.0209158); expected 358.6 (0.02)
Passed bias filter:                      333  (0.0185733); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.23s 00:00:00.75 Elapsed: 00:00:00.40
# Mc/sec: 3370.35
//
Query:       EEA19702.1  [L=106]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.2e-38  128.3   4.0    1.1e-37  128.0   4.0    1.1  1  DUF3759   Protein of unknown function (DUF3759)


Domain annotation for each model (and alignments):
>> DUF3759  Protein of unknown function (DUF3759)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  128.0   4.0   5.9e-42   1.1e-37       2      87 ..      14      98 ..      12     102 .. 0.93

  Alignments for each domain:
  == domain 1  score: 128.0 bits;  conditional E-value: 5.9e-42
     DUF3759  2 ykqvyeeeehkaklshellagAAafeAvkayedhqrkeGkpvshafaKellAgfagaevdklvetkgldeidrekakreAkekaee 87
                y++++++ +h++++shel+agAA++eA+kaye+h++++G+p sha+aKellAgfaga++d+ vet+gld+id ekak eA++++++
  EEA19702.1 14 YQEYQST-KHESSFSHELIAGAASYEAAKAYERHCEANGQPASHAEAKELLAGFAGAFIDREVETRGLDFIDSEKAKYEARRHIDS 98
                4555555.6*************************************************************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (106 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       440  (0.0245412); expected 358.6 (0.02)
Passed bias filter:                      290  (0.0161749); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.34u 0.23s 00:00:00.57 Elapsed: 00:00:00.37
# Mc/sec: 849.04
//
Query:       EEA19703.1  [L=380]
Description: exosome complex exonuclease Rrp4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-13   48.8   1.4    1.2e-12   47.4   1.1    1.9  2  ECR1_N    Exosome complex exonuclease RRP4 N-terminal region
    1.4e-05   25.3   0.6    3.1e-05   24.2   0.6    1.6  1  KH_6      KH domain
     0.0098   16.5   2.0       0.53   10.9   0.1    2.9  3  EXOSC1    Exosome component EXOSC1/CSL4


Domain annotation for each model (and alignments):
>> ECR1_N  Exosome complex exonuclease RRP4 N-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.4   1.1     2e-16   1.2e-12       2      36 ..      54      90 ..      54      92 .. 0.87
   2 ?   -2.7   0.0       0.9   5.4e+03      25      36 ..     301     319 ..     292     320 .. 0.67

  Alignments for each domain:
  == domain 1  score: 47.4 bits;  conditional E-value: 2e-16
                E-TT-EEEETTTSEE-TTEEEETTEE.......EESSSEEEE CS
      ECR1_N  2 VtPGevlttdeefmrGhGTYvrggti.......yAsvaGtve 36
                V+PGe++t d+++mrGhGT+     +       +A+vaGtv+
  EEA19703.1 54 VVPGETVTNDPQWMRGHGTF-----TtpfstsiIATVAGTVS 90
                9*******************.....44555566********8 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 0.9
                 TEE.......EESSSEEEE CS
      ECR1_N  25 gti.......yAsvaGtve 36 
                 ++i       +A +aG ++
  EEA19703.1 301 NEIprqtrreIARLAGCIR 319
                 4455555666888999876 PP

>> KH_6  KH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.2   0.6   5.2e-09   3.1e-05      23      42 ..     250     269 ..     237     273 .. 0.79

  Alignments for each domain:
  == domain 1  score: 24.2 bits;  conditional E-value: 5.2e-09
        KH_6  23 gkagpfeiavGlNGriWvks 42 
                 + +g++ei++G+NG+iW+++
  EEA19703.1 250 NGGGDIEIILGVNGYIWISK 269
                 44599*************97 PP

>> EXOSC1  Exosome component EXOSC1/CSL4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.9   0.1   8.8e-05      0.53       1      26 [.     106     131 ..     106     134 .. 0.93
   2 ?    3.9   0.0     0.013        79      83     108 ..     151     176 ..     149     177 .. 0.91
   3 ?   -2.6   0.0       1.4   8.3e+03      42      58 ..     209     226 ..     196     255 .. 0.57

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 8.8e-05
                 -S-TT-EEEEEEEEEESSEEEEEEEE CS
      EXOSC1   1 lPkegdvVLarvtrlrkkqalveils 26 
                 +P++gd+V +r+++++ ++  v+i +
  EEA19703.1 106 MPEIGDLVVGRIVEVQARRWKVDIAA 131
                 6******************9999975 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.013
                 ECCSSSTT-GGCTEECTTEEEEEEEE CS
      EXOSC1  83 RatekdrvkviemfrpGDIvraqviS 108
                 R t  d+ ++ + f +GD+v a+v S
  EEA19703.1 151 RRTSADELQMRNFFVEGDLVVAEVQS 176
                 77899***************999987 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 1.4
                 TTSS--STS.TTSSCCHC CS
      EXOSC1  42 ngegavkei.eaggglds 58 
                 +g+++ k+  +a+++l++
  EEA19703.1 209 SGSAVSKKSsAAASNLAA 226
                 444444433233333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (380 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       482  (0.0268838); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.23s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2795.24
//
Query:       EEA19704.1  [L=127]
Description: ribosomal protein l7ae, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.9e-07   30.7   0.1    4.4e-07   29.5   0.1    1.5  1  Ribosomal_L7Ae  Ribosomal protein L7Ae/L30e/S12e/Gadd45 famil


Domain annotation for each model (and alignments):
>> Ribosomal_L7Ae  Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.5   0.1   2.5e-11   4.4e-07       5      74 ..      16      93 ..      12      97 .. 0.85

  Alignments for each domain:
  == domain 1  score: 29.5 bits;  conditional E-value: 2.5e-11
                    HHHHHHHHHTEEEESHHH.......HHHHHHTTTESEEEEETTSSSGGHHHHHH.HHHHHTTEEEEEESCHHHHHHHT CS
  Ribosomal_L7Ae  5 evlkkakkagklvlGlke.......vtkalergeaklvilAedvepeekkklle.alckekevpyvkvkskkeLGelv 74
                    + +++a +  +l++G++e        tk ++    + +++A d++p  ++kl+   lc+ek+vp v v  k +LG+++
      EEA19704.1 16 GIVQQATRYHQLKKGVNEddpaiptPTKNVNPSVSERIVMAGDISPLAITKLVRhLLCEEKNVPDVWVLRKTALGQAC 93
                    5678899999999999985554444599999999*****************98626899******************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (127 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       296  (0.0165096); expected 358.6 (0.02)
Passed bias filter:                      287  (0.0160076); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.26s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 930.31
//
Query:       EEA19705.1  [L=380]
Description: hypothetical protein PMAA_004840 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (380 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1278  (0.0712812); expected 358.6 (0.02)
Passed bias filter:                      523  (0.0291706); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.32s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 2473.16
//
Query:       EEA19706.1  [L=795]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-39  135.6   0.2    1.8e-39  135.0   0.2    1.3  1  CRAL_TRIO      CRAL/TRIO domain
    7.3e-11   42.1   0.1    2.5e-10   40.4   0.1    1.9  1  CRAL_TRIO_N    CRAL/TRIO, N-terminal domain
    2.4e-09   37.4   0.1    4.2e-09   36.7   0.1    1.3  1  CRAL_TRIO_2    Divergent CRAL/TRIO domain


Domain annotation for each model (and alignments):
>> CRAL_TRIO  CRAL/TRIO domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  135.0   0.2   3.1e-43   1.8e-39       4     159 .]     290     438 ..     287     438 .. 0.96

  Alignments for each domain:
  == domain 1  score: 135.0 bits;  conditional E-value: 3.1e-43
   CRAL_TRIO   4 leggkvgihgrDkegrpvlylrlgrfdpkklsleelvralvlvlerllkeleedgqvegvtvviDlkglslskmlwkpisllkkilkilqdnyperlgk 102
                  ++gk++ihg D+ grp++ +r++ +  +++s+e l r++v+++e++  +l +   ve++++++D++++s+ +m+   +  +k+++k++++ ype+l  
  EEA19706.1 290 FHMGKNIIHGVDRAGRPIIDIRVRLHRAEDQSVEVLERYIVHTIESVRMLLRP-PFVETAILIFDMTDFSMTNMD---YTPVKYFIKCIENLYPECLAA 384
                 5789*******************************************988888.9********************...********************* PP

   CRAL_TRIO 103 ilivnaPklfkfafklvkpfldektreKikfvspsnteatlekyidpeqlpkelGGt 159
                 i++++aP++f+ ++k++k++++ ++ +K++f+++    ++le++i+++++p+ lGGt
  EEA19706.1 385 IILHKAPWFFSGIWKMIKTWMSDSLVSKVHFTKTL---DDLERFIPRSNIPSDLGGT 438
                 ********************************664...56****************7 PP

>> CRAL_TRIO_N  CRAL/TRIO, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.4   0.1   4.1e-14   2.5e-10      26      53 ..     217     244 ..     193     245 .. 0.87

  Alignments for each domain:
  == domain 1  score: 40.4 bits;  conditional E-value: 4.1e-14
  CRAL_TRIO_N  26 redhddaclLRfLRArkwdvekAikrLe 53 
                  ++dh+da+lLRfLRArkwdv kA+ +L+
   EEA19706.1 217 KHDHPDAMLLRFLRARKWDVGKAFVMLV 244
                  459***********************97 PP

>> CRAL_TRIO_2  Divergent CRAL/TRIO domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.7   0.1     7e-13   4.2e-09       1     132 [.     304     438 ..     304     446 .. 0.82

  Alignments for each domain:
  == domain 1  score: 36.7 bits;  conditional E-value: 7e-13
  CRAL_TRIO_2   1 grpVfvfiaafllsskadldkllryvlhtladk...ivgke....yvlVyfhtglssenkpslswlkkvystlprrykknlkklyivhpstfvktllk 91 
                  grp++ ++ +   ++ ++ + l ry++ht+ +    +  ++     +l++++t++s  +++++  +k +++++++ y++ l +++++ + +f+  + k
   EEA19706.1 304 GRPIIDIRVRLHRAEDQSVEVLERYIVHTI-ESvrmLLRPPfvetAILIFDMTDFSM-TNMDYTPVKYFIKCIENLYPECLAAIILHKAPWFFSGIWK 399
                  567776766666567778999999999999.6657644444555589********97.***************************************6 PP

  CRAL_TRIO_2  92 tvlsafvsskfrkkveyvsrleeLarkidrtqllkslPegv 132
                  ++ + + s  +  kv++  +l +L r+i r +++++l+ g+
   EEA19706.1 400 MIKTWM-SDSLVSKVHFTKTLDDLERFIPRSNIPSDLG-GT 438
                  665555.66677*************************9.54 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (795 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1044  (0.0582297); expected 358.6 (0.02)
Passed bias filter:                      573  (0.0319594); expected 358.6 (0.02)
Passed Vit filter:                       125  (0.00697194); expected 17.9 (0.001)
Passed Fwd filter:                        50  (0.00278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.94u 0.32s 00:00:01.26 Elapsed: 00:00:00.53
# Mc/sec: 4474.90
//
Query:       EEA19707.1  [L=500]
Description: monocarboxylate permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-09   37.8   0.5    1.5e-09   37.3   0.5    1.2  1  Fungal_trans  Fungal specific transcription factor domain
     0.0063   16.7   4.6        1.8    8.8   0.2    3.1  2  YesK          YesK-like protein


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.3   0.5   1.7e-13   1.5e-09       2     209 ..      22     224 ..      21     258 .. 0.81

  Alignments for each domain:
  == domain 1  score: 37.3 bits;  conditional E-value: 1.7e-13
  Fungal_trans   2 drffsnfhpqfpilhkpsflpkt.ssenssksayasplll..lailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilq 95 
                   +++ + f + + +lh p+ l+++  +++++++ ++ + ++  l+++a+G  f++ ++++   s+       +++ + a+++i ++f +++  ++++q
    EEA19707.1  22 QSYMQTFGSIYRVLHIPKSLEEYeLYWSNPETSSQAHVVAklLLVMAIGTVFQPRQEAFVLRSSA------LQWIYVAQTWITTPFDKCRLTIEVIQ 112
                   78999999***************7444444444444444467*****************944333......4555677777788************* PP

  Fungal_trans  96 sLlllelyektssdralher..hhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddd 190
                    L +l ++     d ++  +       ++ a ++gLh + + +    +++ ++ e++ rr+lw ++  + ++ +++ G  pl+++s+ +   P + d
    EEA19707.1 113 -LQCLLIFARLVHDVDGDLLrlSAASLLQTAMQIGLHIDAEIND---FPNISPQEIQLRRNLWAMVLEIVVQMSVDSGGIPLIRASDYDFKSPVNMD 205
                   .6666666666666555555436777778999999999999999...89************************************************ PP

  Fungal_trans 191 dlwesddaseetlvetkls 209
                   d+ + ++++e+    + ++
    EEA19707.1 206 DMVFKNNMDEFVSFIQRPD 224
                   ********99987774444 PP

>> YesK  YesK-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.3   0.4   0.00028       2.5       3      36 ..     299     332 ..     297     369 .. 0.84
   2 !    8.8   0.2    0.0002       1.8      37      68 ..     401     432 ..     392     440 .. 0.87

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00028
        YesK   3 iigiitaillfavsyllkkrfpkkkygiilllil 36 
                 iig+i+  ll+ +s+++k+r p++k  + +++++
  EEA19707.1 299 IIGFIVLALLLPASMFIKSRLPPRKSSLFMPSAF 332
                 7999*********************999998875 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0002
        YesK  37 illslivvlysllvvGGweGmglgilgvsvli 68 
                 +++sl++v+     +G + Gmg+gi ++s li
  EEA19707.1 401 TSISLASVPKDPRNIGTYMGMGFGITAFSTLI 432
                 56888888888999**************9887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (500 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       613  (0.0341904); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.22s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 3719.78
//
Query:       EEA19708.1  [L=161]
Description: hypothetical protein PMAA_004870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (161 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       935  (0.0521501); expected 358.6 (0.02)
Passed bias filter:                      496  (0.0276647); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.35u 0.22s 00:00:00.56 Elapsed: 00:00:00.38
# Mc/sec: 1261.41
//
Query:       EEA19709.1  [L=713]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (713 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       397  (0.0221429); expected 358.6 (0.02)
Passed bias filter:                      353  (0.0196888); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.23s 00:00:00.68 Elapsed: 00:00:00.41
# Mc/sec: 5206.70
//
Query:       EEA19710.1  [L=1422]
Description: Sec7 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-26   93.7   0.0    2.3e-26   92.6   0.0    1.4  1  Sec7      Sec7 domain
    3.1e-19   69.5   0.0    1.4e-18   67.4   0.0    2.0  2  PH_9      Pleckstrin homology domain


Domain annotation for each model (and alignments):
>> Sec7  Sec7 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.6   0.0   2.5e-30   2.3e-26      54     158 ..     723     826 ..     691     846 .. 0.88

  Alignments for each domain:
  == domain 1  score: 92.6 bits;  conditional E-value: 2.5e-30
                 HHCSGGHHHHHHHHHHHCTS--TT--HHHHHHHHCCCS-B-SSHHHHHHHHHHHHHHHHHTTCTC.G-SHHHHHHHHHHHHHHHHHHC-TTSCCS--HH CS
        Sec7  54 ylgkekefnkevlkefvdlfdfsglrldeAlRlflssfrlpgEaqkierilekFaekyfeqnpev.fenadavfvLaysiimLntdlhnpqvkkkmtle 151
                 +lg+    +  ++k++++lf+++++++  AlR++++++ l+gE q+++r+l++++++++e np+  f+  d+v++++ys+++Lntdlh   +++kmt +
  EEA19710.1 723 WLGDAG--RAMIRKAYMELFNWTNMDILAALRSLCTKMALKGETQQVDRVLDALSTRWCECNPNHgFKAVDVVHTICYSLLLLNTDLHMADIDQKMTRN 819
                 666666..7789************************************************9996537999***************************** PP

                 HHHHCTT CS
        Sec7 152 dFiknnr 158
                 +F++n+ 
  EEA19710.1 820 QFVRNTL 826
                 ****975 PP

>> PH_9  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0      0.39   3.5e+03      26      48 ..     916     938 ..     912     950 .. 0.81
   2 !   67.4   0.0   1.5e-22   1.4e-18       1     119 []    1094    1226 ..    1094    1226 .. 0.97

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.39
        PH_9  26 WkevyavlkklvLylykdeeese 48 
                 +k +y  ++k+ L ly+   e+e
  EEA19710.1 916 LKDFYNSIQKQRLPLYNAPAEPE 938
                 789*************9866555 PP

  == domain 2  score: 67.4 bits;  conditional E-value: 1.5e-22
        PH_9    1 ykegivqrkllleskgkktplkkrgWkevyavlkklvLylykdeeesesaetedlks.............lknakllgkirlhhaLaek..asdYkk 82  
                  +keg ++ k++le   kk+  k+r+W+e++av++++ L l+ +  +s+s ++++++              ++na+ + k  l  ++a+   +++Y+k
  EEA19710.1 1094 AKEGSLKHKQHLEAVDKKA--KDRNWNECFAVIQRGWLRLFSFSANSKSMRLKSKQRqggggvvvgggnwMENAEEVWKFLLRQTIASAlpPPGYSK 1188
                  5899***************..******************************9998889******************************999****** PP

        PH_9   83 .kshvFrLqtadgaeylfqtsdakevqeWvdtiNyvAA 119 
                   ++hv +L + +ga+ lfq+++a+ v+e v+t Ny+ A
  EEA19710.1 1189 sRPHVWALSLPTGAVHLFQVGTAEIVREFVTTANYWSA 1226
                  ************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1422 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       567  (0.0316247); expected 358.6 (0.02)
Passed bias filter:                      287  (0.0160076); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.93u 0.34s 00:00:01.27 Elapsed: 00:00:00.54
# Mc/sec: 7928.61
//
Query:       EEA19711.1  [L=374]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.4e-81  274.6   4.4    1.4e-81  274.6   4.4    1.6  2  Ino80_Iec3  IEC3 subunit of the Ino80 complex, chromatin re-m


Domain annotation for each model (and alignments):
>> Ino80_Iec3  IEC3 subunit of the Ino80 complex, chromatin re-modelling
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  274.6   4.4     8e-86   1.4e-81       1     237 []      28     264 ..      28     264 .. 0.97
   2 ?   -2.3   0.7      0.33   5.9e+03      88     104 ..     287     304 ..     267     330 .. 0.48

  Alignments for each domain:
  == domain 1  score: 274.6 bits;  conditional E-value: 8e-86
  Ino80_Iec3   1 kSfkkKYrKlrvkFeekmkesesLikeeqkiedlskRLaeenDqLLdlLldlNnsaqipsslRydLslps..vpsllspeeaaipsleadakgaeaklk 97 
                 +SfkkK++Kl+vkFe +m+ese+L++e+++ied+sk+L+e nDqLL++L+++N+s+ ip++lRydLslp+  +p+++++e+++i+++++++++a+a+lk
  EEA19711.1  28 HSFKKKFAKLKVKFELEMRESEALVREQLRIEDVSKKLQETNDQLLEVLMEFNDSIYIPTNLRYDLSLPGetTPPMTPDEDDDIAPSTYTTTAAKAALK 126
                 6*********************************************************************999************************** PP

  Ino80_Iec3  98 eakeelaageitaedlreleeslkkskafapkkslasLlskvphtslea...peslkdlevgedkeeplgylspeeedeyllalDaklgdeslatstaa 193
                 ea++el+ageita+++r+le+ +k+s+af+p++++asL +  +h+  +a    +  ++l++++ +  ++ y++pe+e+eyllalDak+gd++     a+
  EEA19711.1 127 EARAELEAGEITADTYRRLEKGVKRSTAFRPSMQYASLRQIAQHSGSAAassASIFAELDEDSTTLLNMNYMTPEHEHEYLLALDAKMGDAA-----AE 220
                 ********************************************98888766666777777777889*************************.....99 PP

  Ino80_Iec3 194 aqlrrasekpslaererelelrNpvSvyNWLrkhqPkvFLqdne 237
                 +ql++ ++kp++a+rere++l+Np+SvyNWLr+++P vFLqdne
  EEA19711.1 221 VQLKQLPDKPTFADREREAILQNPNSVYNWLRRNTPYVFLQDNE 264
                 9*****************************************98 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 0.33
  Ino80_Iec3  88 dakgae.aklkeakeela 104
                 ++k  + a++k+a +e++
  EEA19711.1 287 SSKRSSlAASKQAAKEAK 304
                 111111222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (374 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1423  (0.0793686); expected 358.6 (0.02)
Passed bias filter:                      535  (0.0298399); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.30s 00:00:00.90 Elapsed: 00:00:00.50
# Mc/sec: 2266.76
//
Query:       EEA19712.1  [L=366]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.6e-80  270.5   4.1    2.6e-80  270.5   4.1    1.6  2  Ino80_Iec3  IEC3 subunit of the Ino80 complex, chromatin re-m


Domain annotation for each model (and alignments):
>> Ino80_Iec3  IEC3 subunit of the Ino80 complex, chromatin re-modelling
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  270.5   4.1   1.4e-84   2.6e-80       3     237 .]      22     256 ..      20     256 .. 0.96
   2 ?   -2.2   0.8       0.3   5.4e+03      87     104 ..     278     296 ..     258     322 .. 0.47

  Alignments for each domain:
  == domain 1  score: 270.5 bits;  conditional E-value: 1.4e-84
  Ino80_Iec3   3 fkkKYrKlrvkFeekmkesesLikeeqkiedlskRLaeenDqLLdlLldlNnsaqipsslRydLslps..vpsllspeeaaipsleadakgaeaklkea 99 
                 ++kK++Kl+vkFe +m+ese+L++e+++ied+sk+L+e nDqLL++L+++N+s+ ip++lRydLslp+  +p+++++e+++i+++++++++a+a+lkea
  EEA19712.1  22 YRKKFAKLKVKFELEMRESEALVREQLRIEDVSKKLQETNDQLLEVLMEFNDSIYIPTNLRYDLSLPGetTPPMTPDEDDDIAPSTYTTTAAKAALKEA 120
                 9*******************************************************************999**************************** PP

  Ino80_Iec3 100 keelaageitaedlreleeslkkskafapkkslasLlskvphtslea...peslkdlevgedkeeplgylspeeedeyllalDaklgdeslatstaaaq 195
                 ++el+ageita+++r+le+ +k+s+af+p++++asL +  +h+  +a    +  ++l++++ +  ++ y++pe+e+eyllalDak+gd++     a++q
  EEA19712.1 121 RAELEAGEITADTYRRLEKGVKRSTAFRPSMQYASLRQIAQHSGSAAassASIFAELDEDSTTLLNMNYMTPEHEHEYLLALDAKMGDAA-----AEVQ 214
                 ******************************************98888766666777777777889*************************.....999* PP

  Ino80_Iec3 196 lrrasekpslaererelelrNpvSvyNWLrkhqPkvFLqdne 237
                 l++ ++kp++a+rere++l+Np+SvyNWLr+++P vFLqdne
  EEA19712.1 215 LKQLPDKPTFADREREAILQNPNSVYNWLRRNTPYVFLQDNE 256
                 ****************************************98 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.3
  Ino80_Iec3  87 adakgae.aklkeakeela 104
                  ++k  + a++k+a +e++
  EEA19712.1 278 RSSKRSSlAASKQAAKEAK 296
                 1111111222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (366 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1452  (0.0809861); expected 358.6 (0.02)
Passed bias filter:                      550  (0.0306766); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 2398.01
//
Query:       EEA19713.1  [L=385]
Description: RNA binding protein Rnp24, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.8e-22   77.3   0.6    8.2e-13   48.0   0.0    3.4  2  RRM_1            RNA recognition motif. (a.k.a. RRM, RBD, or 
     0.0014   18.6   0.3       0.44   10.6   0.0    2.6  2  Nup35_RRM_2      Nup53/35/40-type RNA recognition motif
  ------ inclusion threshold ------
      0.025   14.2   0.9      0.025   14.2   0.9    1.9  2  Spt20            Spt20 family
      0.031   15.2  14.9      0.031   15.2  14.9    2.2  2  Spt5_N           Spt5 transcription elongation factor, acidic
      0.066   13.3   0.0       0.83    9.8   0.0    2.5  2  RRM_7            RNA recognition motif
       0.26    9.3  11.7       0.37    8.8  11.7    1.2  1  DNA_pol_phi      DNA polymerase phi
       0.66    9.2   7.6      0.026   13.8   1.1    1.8  2  ORC6             Origin recognition complex subunit 6 (ORC6)
        1.2    8.9  15.0       0.12   12.2   4.5    2.3  2  RR_TM4-6         Ryanodine Receptor TM 4-6
        2.6    7.4   4.9       0.23   10.9   0.2    1.5  2  GNAT_acetyltr_2  GNAT acetyltransferase 2
        2.8    8.0  26.1      0.065   13.3  14.5    2.3  2  YL1              YL1 nuclear protein
        3.5    6.1   6.0        6.1    5.3   6.0    1.3  1  RRN3             RNA polymerase I specific transcription init
        4.3    8.3  20.7       0.13   13.1   9.8    2.8  2  GEN1_C           Holliday junction resolvase Gen1 C-terminal 
        7.5    6.2  14.2      0.098   12.3   5.8    2.0  2  CCDC106          Coiled-coil domain-containing protein 106


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.3   0.1   1.4e-08     2e-05       1      69 [.      79     155 ..      79     156 .. 0.81
   2 !   48.0   0.0   5.9e-16   8.2e-13       1      57 [.     193     250 ..     193     254 .. 0.97

  Alignments for each domain:
  == domain 1  score: 24.3 bits;  conditional E-value: 1.4e-08
                 EEEESETTTSSHHHHHHHHHT.T....SCEEEEEEEEE....TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFsk.f....Gpiksiklvrd....etgkskgfafVeFeskedAekAlealngkklggrel 69 
                 +++gn p+++t+e++++++ + +      i++i ++         ++kgfa+V+F++k ++e+A+  l +k + gr++
  EEA19713.1  79 VWIGNMPFTATKEDVRKFLLDgCtfseATITRIHIPMGpsrgFIPQNKGFAYVDFANKKAMEEAIG-LSEKFIAGRRV 155
                 68999999999999999975522222256778888888855556689*******************.*******9986 PP

  == domain 2  score: 48.0 bits;  conditional E-value: 5.9e-16
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHH CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAle 57 
                 +fVgnL +d+t+e ++e+F ++G+i+++ l +    gk kg++ VeFe+ e+A++A +
  EEA19713.1 193 IFVGNLGFDATKEAVEEHFAPCGSITNVHLATFeDSGKCKGYGWVEFETIEAATHAAN 250
                 8*******************************99*********************975 PP

>> Nup35_RRM_2  Nup53/35/40-type RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.1     0.012        17      27      52 ..     108     142 ..      87     143 .. 0.78
   2 !   10.6   0.0   0.00032      0.44      13      50 ..     203     246 ..     199     248 .. 0.78

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.012
  Nup35_RRM_2  27 Ivkhyvp.........kevsvmyvkfesekdaekA 52 
                  I+++ +p         +++ ++yv f+++k+ e A
   EEA19713.1 108 ITRIHIPmgpsrgfipQNKGFAYVDFANKKAMEEA 142
                  67777777778888878899***********9988 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00032
  Nup35_RRM_2  13 lielVlehFasfGeIvkhyvp......kevsvmyvkfesekdae 50 
                  ++e V ehFa +G I++          k + + +v+fe+  +a 
   EEA19713.1 203 TKEAVEEHFAPCGSITNVHLAtfedsgKCKGYGWVEFETIEAAT 246
                  5678999**********555557788888889999999877776 PP

>> Spt20  Spt20 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.2      0.54   7.4e+02     132     149 ..      51      68 ..       8      82 .. 0.53
   2 ?   14.2   0.9   1.8e-05     0.025     126     173 ..     259     306 ..     239     331 .. 0.76

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.54
       Spt20 132 eqqqqqnekdsttteeke 149
                 e++++++e+d+++t++k+
  EEA19713.1  51 EKTEVKSETDTNETTTKN 68 
                 222222222222222222 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 1.8e-05
       Spt20 126 qqqqqqeqqqqqnekdsttteekekksksknnssksktttkkpkvyrt 173
                 ++++++e++ ++++ ++ +++e+ +k+k+++++sk+ tttkkp+++++
  EEA19713.1 259 EEEEEEEESDDDSSSEDGESDEEGEKKKKEKKKSKKVTTTKKPRMKKV 306
                 33334555555555566667777788888888899999*******987 PP

>> Spt5_N  Spt5 transcription elongation factor, acidic N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.3       6.8   9.4e+03      53      53 ..      49      49 ..       6      76 .. 0.54
   2 ?   15.2  14.9   2.3e-05     0.031      10      88 ..     259     346 ..     252     365 .. 0.54

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 6.8
                X CS
      Spt5_N 53 r 53
                 
  EEA19713.1 49 P 49
                1 PP

  == domain 2  score: 15.2 bits;  conditional E-value: 2.3e-05
                 XXXXXXXXXXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXXXXXX........XXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
      Spt5_N  10 ddeeeeeeeeeveggedd.fiaeeeaeeeeedserddrshreldrrr........qaeed.edaeeiaealeeRYgrsskkayrgeaee 88 
                 ++e eeeee++++   +d   +ee +++++e++++++    +  r +         ++ + e ae  a ++++R+g+ skk  +ge e 
  EEA19713.1 259 EEE-EEEEESDDDSSSEDgESDEEGEKKKKEKKKSKKVTTTKKPRMKkvwvnrllGRQLRmEFAEDAATRYKKRFGKDSKKGGDGENEG 346
                 222.2333333222222211122222222222222222222222222355555543333348899************999999998876 PP

>> RRM_7  RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0      0.53   7.3e+02       4      65 ..      79     141 ..      77     148 .. 0.52
   2 ?    9.8   0.0    0.0006      0.83       1      29 [.     190     218 ..     190     258 .. 0.81

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.53
       RRM_7   4 vFvGGlPiDiteeelka......tfkefgkvlvdwPkkaeskkkaaenskaakgyvflvfedeksvka 65 
                 v++G +P   t+e++ +      tf+e   +++  P  +           ++kg++++ f ++k++++
  EEA19713.1  79 VWIGNMPFTATKEDVRKflldgcTFSEATITRIHIPMGPSRGFIP-----QNKGFAYVDFANKKAMEE 141
                 566666666666666541111113333333333333333332222.....357888888888887765 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.0006
       RRM_7   1 srkvFvGGlPiDiteeelkatfkefgkvl 29 
                 sr++FvG l  D t+e++++ f   g+++
  EEA19713.1 190 SRRIFVGNLGFDATKEAVEEHFAPCGSIT 218
                 89********************9999864 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8  11.7   0.00027      0.37     641     700 ..     255     327 ..     240     349 .. 0.61

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00027
  DNA_pol_phi 641 ededeeddeeeeeeddeededseedddeeesdedeededdedvdeid...............elreklaealges 700
                    edee++eeee++dd+++ed e+d++ e+++++++++++  ++  +               +lr++ ae+  + 
   EEA19713.1 255 IPEDEEEEEEEESDDDSSSEDGESDEEGEKKKKEKKKSKKVTTT--KkprmkkvwvnrllgrQLRMEFAEDAATR 327
                  45666666666666666666666666666555555544444443..23577777777777776766666665554 PP

>> ORC6  Origin recognition complex subunit 6 (ORC6)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.7      0.88   1.2e+03      90     122 ..      29      65 ..       6      97 .. 0.54
   2 ?   13.8   1.1   1.9e-05     0.026     105     221 ..     164     311 ..     136     340 .. 0.79

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.88
        ORC6  90 satstPskspsspst....dpkslrkqlfsTPtKskt 122
                 sa++ Psk+  ++ +    dp + ++    T t ++t
  EEA19713.1  29 SAPEPPSKKALRKAKkkgiDPTEKTEVKSETDTNETT 65 
                 3344444443333333444333333333333333333 PP

  == domain 2  score: 13.8 bits;  conditional E-value: 1.9e-05
        ORC6 105 dpkslrkqlfsTPtKsktlktalsasksssplkrrrklaneedgeeeeed.apswvstsir.................................dsrpe 169
                 + +++++q+ +++tK  + +t+    + +s++    +l ++  +e  ee  ap  + t+ +                                  +++e
  EEA19713.1 164 EGRPTEHQQAGGATKAGAAATS---AHPPSRRIFVGNLGFDATKEAVEEHfAPCGSITNVHlatfedsgkckgygwvefetieaathaangfvkIPEDE 259
                 6788999999*****9999999...77889999999*****************99999999******************************97655555 PP

        ORC6 170 isrtlspskslgdesilfndss..ddekkseqksprkllkkkkdkisdediiel 221
                 +++++++s+   d+s+++ +s    ++kk+e+k+++k++ +kk +++++ +++l
  EEA19713.1 260 EEEEEEESD--DDSSSEDGESDeeGEKKKKEKKKSKKVTTTKKPRMKKVWVNRL 311
                 555544444..4444444444355889999999999999999999998766665 PP

>> RR_TM4-6  Ryanodine Receptor TM 4-6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   2.8     0.075     1e+02      65     122 ..      13      71 ..       3      94 .. 0.51
   2 ?   12.2   4.5   8.4e-05      0.12      94     144 ..     254     302 ..     167     363 .. 0.71

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.075
                 XXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXX CS
    RR_TM4-6  65 kseagLgDlseteaeespt.pelkkklaeeeeaeeekeeeeepeaeaeekadaengeke 122
                 +++  L D+ e e   s++ p  kk l +++++     e++e ++e+  ++++ ++ ke
  EEA19713.1  13 HKKRKLDDVPEIEIDVSAPePPSKKALRKAKKKGIDPTEKTEVKSETDTNETTTKNGKE 71 
                 33334777777766655433444444444444444444444444444222222222222 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 8.4e-05
                 XXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXX..........XXXXXXX CS
    RR_TM4-6  94 eeaeeekeeeeepeaeaeekadaengekeekekekeeeekeseeeeeekkk 144
                 ++ e+e+eeeee++ ++  ++d e+ e+ ek+k+  e++k++++ +++k+ 
  EEA19713.1 254 KIPEDEEEEEEEESDDDSSSEDGESDEEGEKKKK--EKKKSKKVTTTKKPR 302
                 3444444444444444444445444444444433..222222222222222 PP

>> GNAT_acetyltr_2  GNAT acetyltransferase 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   0.7       6.8   9.3e+03     138     140 ..      57      58 ..      35      76 .. 0.39
   2 ?   10.9   0.2   0.00016      0.23      87     179 ..     208     305 ..     197     310 .. 0.59

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 6.8
  GNAT_acetyltr_2 138 eee 140
                      + e
       EEA19713.1  57 S-E 58 
                      1.1 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00016
  GNAT_acetyltr_2  87 deefaslsGaRivRiAvhpel.qkmGYGsralelle...kyyegklssleeeeekeeeeeeekeeeee.klsleeeklkprkelpplllklsee 175
                      +e+fa    +  v +A+ ++  + +GYG    e +e   +  +g ++  e+eee+eeee+++ +++e+ ++++e ek k++k+  + ++++++ 
       EEA19713.1 208 EEHFAPCGSITNVHLATFEDSgKCKGYGWVEFETIEaatHAANGFVKIPEDEEEEEEEESDDDSSSEDgESDEEGEKKKKEKKKSKKVTTTKKP 301
                      5667766667778888866551568999866666551105556655555555555555544444444445666666666666666666666665 PP

  GNAT_acetyltr_2 176 kpek 179
                      +++k
       EEA19713.1 302 RMKK 305
                      5555 PP

>> YL1  YL1 nuclear protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   3.6      0.47   6.5e+02      79     125 ..      32      75 ..       4      95 .. 0.34
   2 ?   13.3  14.5   4.7e-05     0.065      42     110 ..     257     306 ..     237     380 .. 0.44

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.47
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...............xxxxxxxxxxx RF
         YL1  79 erkkrkkekkkrkaqkkkskkkkkkqkkkkkkkidp...............qakeprpkkks 125
                 e   +k+                   +k+kkk idp               ++k+ ++ k+s
  EEA19713.1  32 EPPSKKAL------------------RKAKKKGIDPtektevksetdtnetTTKNGKEGKRS 75 
                 22222111..................111111111111111111111111111122444444 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 4.7e-05
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         YL1  42 eeeeeensDsdfdsdeedeesdeeedeeegekelerqerkkr.....kkekkkrkaqkkkskkkkkkqkkkkkk 110
                 e+eeee ++   +++++d +s+++e +eegek+ ++++++k+     k            +++        kk+
  EEA19713.1 257 EDEEEE-EE---EESDDDSSSEDGESDEEGEKKKKEKKKSKKvtttkK------------PRM--------KKV 306
                 333332.12...122222233444455566664222222222322111............111........222 PP

>> RRN3  RNA polymerase I specific transcription initiation factor RRN3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   6.0    0.0044       6.1     239     274 ..     258     294 ..     236     311 .. 0.40

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0044
        RRN3 239 edddeddeesdlddlssdeeaeedee.kdeeeeslkk 274
                 ++++e++eesd+d+ s+d e +e+ e k++e+++ kk
  EEA19713.1 258 DEEEEEEEESDDDSSSEDGESDEEGEkKKKEKKKSKK 294
                 1111111112222222222222221111111111111 PP

>> GEN1_C  Holliday junction resolvase Gen1 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   1.4      0.41   5.7e+02      62      82 ..      30      53 ..       3      81 .. 0.58
   2 ?   13.1   9.8   9.7e-05      0.13      28      89 ..     251     311 ..     246     323 .. 0.70

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.41
      GEN1_C 62 e...eeasakkkrkkkpydPsepe 82
                +    +++a +k+kkk  dP+e+ 
  EEA19713.1 30 ApepPSKKALRKAKKKGIDPTEKT 53
                143345555666666666776654 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 9.7e-05
      GEN1_C  28 qlVaidlsgeegkreepagreglaededdedeeeeeeasakkkrkkkpydPseperiWipes 89 
                  +V+i +++ee+++ee ++++  +ed ++++e e++++++kk +k +++   + +++W+ + 
  EEA19713.1 251 GFVKIPEDEEEEEEEE-SDDDSSSEDGESDEEGEKKKKEKKKSKKVTTTKKPRMKKVWVNRL 311
                 5899999999999998.555555666555555554555555556666666667789999765 PP

>> CCDC106  Coiled-coil domain-containing protein 106
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   1.2       1.7   2.3e+03      79      88 ..      50      59 ..       7      79 .. 0.46
   2 ?   12.3   5.8   7.1e-05     0.098      76     124 ..     257     306 ..     238     337 .. 0.51

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.7
     CCDC106 79 sddsssdsse 88
                +++++ +s++
  EEA19713.1 50 TEKTEVKSET 59
                1111111111 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 7.1e-05
     CCDC106  76 seesddsssdssessessegsstekkkkkkkk.kekkkkkktkkrerkrv 124
                 ++e+++++ +s + s+s++g+s+e+  kkkk+ k+ kk + tkk   k+v
  EEA19713.1 257 EDEEEEEEEESDDDSSSEDGESDEEGEKKKKEkKKSKKVTTTKKPRMKKV 306
                 33333444444444444444444443333321133333333333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (385 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1752  (0.0977188); expected 358.6 (0.02)
Passed bias filter:                      774  (0.0431703); expected 358.6 (0.02)
Passed Vit filter:                       172  (0.0095934); expected 17.9 (0.001)
Passed Fwd filter:                        42  (0.00234257); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.76u 0.29s 00:00:01.05 Elapsed: 00:00:00.48
# Mc/sec: 2431.46
//
Query:       EEA19714.1  [L=693]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.8e-29  102.0   4.6    6.4e-29  100.8   4.6    1.6  1  Btz       CASC3/Barentsz eIF4AIII binding


Domain annotation for each model (and alignments):
>> Btz  CASC3/Barentsz eIF4AIII binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.8   4.6   3.6e-33   6.4e-29       4     114 ..     134     242 ..     131     255 .. 0.86

  Alignments for each domain:
  == domain 1  score: 100.8 bits;  conditional E-value: 3.6e-33
         Btz   4 eesqsgrepsaeekeeked..eerkrseaekkekeddsnPafvPkrGaFylHDdRtaeteangvrefeks.srvaglivaskvarrklkdaaeedrWtH 99 
                  +++ gr+psa+++e +++  +erkr+e+e++ k +d+nPafvP+rG F+lHD+R+ + +   v   +ks sr++gliv+++v  r+  d a++++WtH
  EEA19714.1 134 TKDKIGRTPSAPPTESRREtfAERKRREHEEYIKARDENPAFVPTRGGFFLHDKRSVDGPRSHV---NKSkSRPYGLIVDGNV-GRRKTD-ASDGQWTH 227
                 5678899**************************************************9885533...3455************.555444.4489**** PP

         Btz 100 Drfeevaseqapksr 114
                 D++++v+ +++p++ 
  EEA19714.1 228 DLHDTVVRDDRPTNS 242
                 ************973 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (693 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       334  (0.018629); expected 358.6 (0.02)
Passed bias filter:                      180  (0.0100396); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.50
# Mc/sec: 4203.74
//
Query:       EEA19715.1  [L=835]
Description: ZZ type zinc finger domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      4e-31  107.8   0.2    1.3e-30  106.1   0.2    2.0  1  N_BRCA1_IG  Ig-like domain from next to BRCA1 gene
    2.2e-23   81.8  49.7    1.7e-08   34.1   8.0    4.4  4  ZZ          Zinc finger, ZZ type
  ------ inclusion threshold ------
        1.3    9.4  46.4        0.7   10.3   5.5    4.5  4  C1_2        C1 domain


Domain annotation for each model (and alignments):
>> N_BRCA1_IG  Ig-like domain from next to BRCA1 gene
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.1   0.2   2.2e-34   1.3e-30       1     102 []     600     713 ..     600     713 .. 0.97

  Alignments for each domain:
  == domain 1  score: 106.1 bits;  conditional E-value: 2.2e-34
  N_BRCA1_IG   1 tipdgtvvppgteftktWrlrNtGseaWpagtklvfvgGdkmgs............asaeessvsvpavapgeevevsvelkaPskpgryisywrlate 87 
                 t++dgt+++p++ f++tW+l N G+++Wp gt++++vgGd+m++            a a++s+  v++vap e++++sv+lk+P++ g+ isywr++ +
  EEA19715.1 600 TVSDGTAMAPSQVFQQTWTLYNPGPTTWPVGTSVRYVGGDAMFNintehpssvvalAVAMSSNELVHPVAPSESADFSVTLKTPQRIGSSISYWRMKLP 698
                 899***************************************9669*********988899999*********************************** PP

  N_BRCA1_IG  88 dgseFGdrlwvdieV 102
                 +g+ FG++lw+d++V
  EEA19715.1 699 NGTPFGHKLWCDVKV 713
                 *************98 PP

>> ZZ  Zinc finger, ZZ type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.1   9.6   5.2e-06     0.031       6      35 ..     207     237 ..     203     242 .. 0.85
   2 !   25.4   7.4   1.5e-09   8.8e-06       4      44 ..     318     357 ..     316     358 .. 0.90
   3 !   34.1   8.0   2.9e-12   1.7e-08       2      43 ..     387     428 ..     386     430 .. 0.89
   4 !   25.7   1.4   1.2e-09   7.3e-06      15      43 ..     467     496 ..     460     498 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 5.2e-06
                 E-TTT-S..EESSEEEESSSS..S-EE-HHHH CS
          ZZ   6 tCdgCseapligvRyhclrcs..dYDLCqsCf 35 
                  C+ C+   +    yhc +c+  dYDLC +C 
  EEA19715.1 207 DCNNCGG-SIPSEHYHCGICDdgDYDLCLNCV 237
                 7******.777889******9455*******6 PP

  == domain 2  score: 25.4 bits;  conditional E-value: 1.5e-09
                 -EE-TTT-S..EESSEEEESSSSS-EE-HHHHHH.H---SS CS
          ZZ   4 kytCdgCseapligvRyhclrcsdYDLCqsCfsthkagkhk 44 
                 + tC+ C    +    +hc  c+dYDLC++C  + ++++h 
  EEA19715.1 318 ERTCNACFREFSESSMVHCDNCEDYDLCIGCLLK-NSHGHN 357
                 569******8889999*****************9.999996 PP

  == domain 3  score: 34.1 bits;  conditional E-value: 2.9e-12
                 SS-EE-TTT-S..EESSEEEESSSSS-EE-HHHHHH..H---S CS
          ZZ   2 hkkytCdgCseapligvRyhclrcsdYDLCqsCfst.hkagkh 43 
                 h++++CdgC +  ++gvR +cl+c+d+D C sC +t   ++++
  EEA19715.1 387 HHAAICDGCEK-RIVGVRHKCLSCPDWDYCWSCAKTaDQSHPQ 428
                 99*********.**********************997555544 PP

  == domain 4  score: 25.7 bits;  conditional E-value: 1.2e-09
                 EESSEEEESSSSS-EE-HHHHHH..H---S CS
          ZZ  15 ligvRyhclrcsdYDLCqsCfst.hkagkh 43 
                 + gvRy+c++c d+D C  C+    +++++
  EEA19715.1 467 ITGVRYKCAVCHDTDFCAACEALpTNTHNQ 496
                 679*****************9887777775 PP

>> C1_2  C1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   7.9    0.0002       1.2      19      47 .]     206     237 ..     188     237 .. 0.74
   2 ?   10.3   5.5   0.00012       0.7      13      46 ..     313     348 ..     306     349 .. 0.86
   3 ?    5.7   5.3    0.0031        18      11      47 .]     382     419 ..     370     419 .. 0.84
   4 ?    2.1   3.9     0.041   2.5e+02      24      46 ..     458     486 ..     424     487 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.0002
        C1_2  19 fnCsaCgrkidgffYsCseCd...fslhvrCa 47 
                   C+ Cg +i +++Y+C +Cd   + l+ +C+
  EEA19715.1 206 IDCNNCGGSIPSEHYHCGICDdgdYDLCLNCV 237
                 56999999998888******6677*******6 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00012
        C1_2  13 edssesfnCsaCgrk.idgffYsCseC.dfslhvrC 46 
                 ++  ++++C+aC r+ +++++ +C+ C d+ l++ C
  EEA19715.1 313 KEVADERTCNACFREfSESSMVHCDNCeDYDLCIGC 348
                 5667889********777777******88*****99 PP

  == domain 3  score: 5.7 bits;  conditional E-value: 0.0031
        C1_2  11 kgedssesfnCsaCgrkidgffYsCseC.dfslhvrCa 47 
                  g+ ++    C++C++ i g + +C  C d   + +Ca
  EEA19715.1 382 PGRHYHHAAICDGCEKRIVGVRHKCLSCpDWDYCWSCA 419
                 5677788889*******99*********9999999998 PP

  == domain 4  score: 2.1 bits;  conditional E-value: 0.041
        C1_2  24 Cgrk.....idgffYsCseC.dfslhvrC 46 
                 C+ k     i+g +Y+C  C d  ++  C
  EEA19715.1 458 CRGKpstsyITGVRYKCAVChDTDFCAAC 486
                 66665555567778***99*889999988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (835 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       922  (0.0514251); expected 358.6 (0.02)
Passed bias filter:                      459  (0.025601); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.64u 0.28s 00:00:00.92 Elapsed: 00:00:00.49
# Mc/sec: 5137.93
//
Query:       EEA19716.1  [L=534]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (534 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       484  (0.0269954); expected 358.6 (0.02)
Passed bias filter:                      384  (0.0214178); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 3796.31
//
Query:       EEA19717.1  [L=229]
Description: short chain type dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.7e-14   52.8   0.2      5e-14   52.4   0.2    1.1  1  adh_short_C2    Enoyl-(Acyl carrier protein) reductase
    1.6e-13   50.5   0.2    3.2e-13   49.6   0.3    1.4  1  adh_short       short chain dehydrogenase
    0.00038   20.0   0.0    0.00072   19.1   0.0    1.5  2  Epimerase       NAD dependent epimerase/dehydratase family
  ------ inclusion threshold ------
      0.013   15.4   0.2      0.019   14.9   0.2    1.5  1  NAD_binding_10  NAD(P)H-binding
      0.039   14.2   0.0        8.5    6.7   0.0    2.2  2  AAA_22          AAA domain
       0.08   12.0   0.0       0.11   11.5   0.0    1.3  1  RmlD_sub_bind   RmlD substrate binding domain
      0.097   12.3   0.2       0.89    9.2   0.1    2.2  2  ApbA            Ketopantoate reductase PanE/ApbA
      0.099   12.0   0.0       0.21   10.9   0.0    1.5  1  2-Hacid_dh_C    D-isomer specific 2-hydroxyacid dehydrogenase
       0.11   13.1   0.0       0.37   11.4   0.0    2.0  2  F420_oxidored   NADP oxidoreductase coenzyme F420-dependent


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.4   0.2   2.5e-17     5e-14       1     158 [.      10     168 ..      10     176 .. 0.89

  Alignments for each domain:
  == domain 1  score: 52.4 bits;  conditional E-value: 2.5e-17
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSE.E.EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHH CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneeakkrveelaeelgae.v.lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreef 95 
                   Ga   IG+a+ +++ ++G++v+l+ +  ++   +    +e++   + +++D +++++v++l+e+v++++g   +++ na ++ +  +   +++ e f
    EEA19717.1  10 GAGANIGQAVGRKFTANGYKVALASRTASD---TS--NQETKDGlFhFRVDLSNPTNVKTLFEQVQNSLGVPSVVIYNASHTVR-GETPFSITPEAF 100
                   77899*******************999998...33..3333333246*************************************.66668899**** PP

                   HHHHHHHTHHHHHHHHHHHH...HCTSC..CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHH CS
  adh_short_C2  96 draldvnlyslfllakaalp...lmkeg..gsivnlssvgaervvpnynaygaaKaalealtrylAve 158
                   +++l+v ++s+f+ a++a++    + ++   s + +     e+++++ +  ga K a  +l++++A++
    EEA19717.1 101 QETLNVITTSAFAAAQEAVRgfeTLPKSspKSFLFTGNALDEIIIQGMAPAGAGKSATAHLMKAAAAS 168
                   ********************8875555569***********************************975 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.6   0.3   1.6e-16   3.2e-13       2     165 ..       5     167 ..       4     173 .. 0.88

  Alignments for each domain:
  == domain 1  score: 49.6 bits;  conditional E-value: 1.6e-16
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGG.GCSHH CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfs.elsee 99 
                 ++lv Ga++ IG+a+ +++ ++G+kv++++r++++     +e k   + +++++vD+++ ++v++l+e++++ lg   v++ NA+ t +g++  +++ e
  EEA19717.1   5 IALVLGAGANIGQAVGRKFTANGYKVALASRTASDT--SNQETK---DGLFHFRVDLSNPTNVKTLFEQVQNSLGVPSVVIYNASHTVRGETPfSITPE 98 
                 79******************************9988..445555...459************************************5555444278999 PP

                 HHHHHHHHHTHHHHHHHHHHHHHHH...HCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHH CS
   adh_short 100 ewervievNltgvflltravlpaml...kqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslak 165
                 +++++++v  t++f +++++++ +    k+s  +  +++    +    g+a+ +A K a a+l++++a 
  EEA19717.1  99 AFQETLNVITTSAFAAAQEAVRGFEtlpKSSPKSFLFTGNALDEIIIQGMAPAGAGKSATAHLMKAAAA 167
                 9********************998877788888999999999999999999999999999999998775 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   3.6e-07   0.00072       1      66 [.       6      72 ..       6     137 .. 0.72
   2 ?   -2.6   0.0       1.6   3.1e+03      16      35 ..     169     188 ..     164     211 .. 0.73

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 3.6e-07
                EEEETTTSHHHHHHHHHHHHCTSEEEEEES-ST.TTTCHHCHHCEEEE--TT-HHHHHHHHHHHT-S CS
   Epimerase  1 ilVtGatGfiGsalvkallekgyevigldrlss.asntarledlelveldltdrsalerlfkeeqpd 66
                +lV+Ga   iG+a+ +++ ++gy+v   +r  s +sn++ ++ l   ++dl ++++++ lf+++q  
  EEA19717.1  6 ALVLGAGANIGQAVGRKFTANGYKVALASRTASdTSNQETKDGLFHFRVDLSNPTNVKTLFEQVQNS 72
                59**********************88887775404455555555889***************98744 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.6
                 HHHHHCTSEEEEEES-STTT CS
   Epimerase  16 kallekgyevigldrlssas 35 
                 +  lekgy+   +d ++s++
  EEA19717.1 169 ETYLEKGYTFYYVDERTSGG 188
                 66788899999888887765 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   0.2   9.5e-06     0.019       1      68 [.      10      83 ..      10     174 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 9.5e-06
                    TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHHCTTTCEEEE--TT-CCHHHHHHT......T-S.EEEES- CS
  NAD_binding_10  1 GAtGkvGrllvkellargghevtalvRnpeklaeleaeeglevvegdvtdvedlaealk......gad.aVvsal 68
                    GA  ++G+++ ++  a+ g++v +  R+++++++ e ++gl  + +d++++  ++  ++      g+  +V+ ++
      EEA19717.1 10 GAGANIGQAVGRKFTAN-GYKVALASRTASDTSNQETKDGLFHFRVDLSNPTNVKTLFEqvqnslGVPsVVIYNA 83
                    89999************.5**************99999*****************99993333333322444444 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.0    0.0087        17      39      68 ..      46      77 ..      21     105 .. 0.80
   2 ?    6.7   0.0    0.0042       8.5      12      48 ..     149     184 ..     144     221 .. 0.70

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0087
      AAA_22 39 rpevv..fvtlpsstsskdllrellralglel 68
                +++++  +v+l+++t+ k+l++++ + lg++ 
  EEA19717.1 46 KDGLFhfRVDLSNPTNVKTLFEQVQNSLGVPS 77
                44444559********************9875 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0042
      AAA_22  12 GesGtGKTtllrrlleqldeeakaeeerpevvfvtlp 48 
                 +++G+GK+ ++  ++  +  e + e+ + ++++v+  
  EEA19717.1 149 APAGAGKSATAHLMKAAAASETYLEK-GYTFYYVDER 184
                 79*************99865554443.4444444433 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   5.8e-05      0.11       4      61 ..       7      85 ..       5     119 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 5.8e-05
                   EEESTTSHHHHHHHHHCTTTSEEEEEE-TT................T--TTSHHHHHHHHHHH-.....-SEEEE---- CS
  RmlD_sub_bind  4 lvtGanGqlGseLakqlaeeglevlaltre................eldltdaeavaellkeak.....pdvvvnaAAy 61
                   lv+Ga+  +G+++ ++++++g++v   +r+                ++dl+++++v++l+++++     p+vv+  A +
     EEA19717.1  7 LVLGAGANIGQAVGRKFTANGYKVALASRTasdtsnqetkdglfhfRVDLSNPTNVKTLFEQVQnslgvPSVVIYNASH 85
                   89*******************9998888888999999999999999999999999999999987223334456655555 PP

>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.1   0.00045      0.89       2      37 ..       7      44 ..       6      81 .. 0.73
   2 ?    0.7   0.0      0.18   3.6e+02     119     147 ..     143     172 ..     133     175 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00045
                EEES-SH.HHHHHHHHHHHHTHCEEEE-SCH.HHHHHH CS
        ApbA  2 ailGaGa.iGsllaakLakagadvtlilrsr.rlealk 37
                ++lGaGa iG+ ++ k +++g++v l  r++    + +
  EEA19717.1  7 LVLGAGAnIGQAVGRKFTANGYKVALASRTAsDTSNQE 44
                69****88*********************995444322 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.18
                 EEEEEEEE-EEEEEETTEEEECS.--EEEE CS
        ApbA 119 rvlggvtthgatregpgevhhag.kgeiki 147
                  +++g+ + ga+++++ ++  a+   e+++
  EEA19717.1 143 IIIQGMAPAGAGKSATAHLMKAAaASETYL 172
                 589************999977764666666 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00011      0.21      41      75 ..       8      43 ..       4      56 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00011
                  EES-S.HHHHHHHHHHHHTT-EEEEESSSHHHHHCH CS
  2-Hacid_dh_C 41 iiGlG.rIGqavakrlkafgmkviaydrskkkeeee 75
                  ++G+G +IGqav ++++a g kv   +r+ ++++++
    EEA19717.1  8 VLGAGaNIGQAVGRKFTANGYKVALASRTASDTSNQ 43
                  7888856**********************9977732 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00019      0.37       4      43 ..       7      44 ..       4      70 .. 0.81
   2 ?   -2.7   0.0       4.8   9.5e+03      76      81 ..     102     107 ..      93     123 .. 0.41

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00019
                   EE.TTS.HHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHH CS
  F420_oxidored  4 ii.GaG.nmgealasgllaagaqpheivvansrnpekaeela 43
                   ++ GaG n+g+a+ ++++a+g   +++ +a sr+ +     +
     EEA19717.1  7 LVlGAGaNIGQAVGRKFTANG---YKVALA-SRTASDTSNQE 44
                   44499978*************...****88.99887766555 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 4.8
                    HHHHHC CS
  F420_oxidored  76 evlsel 81 
                    e+l+ +
     EEA19717.1 102 ETLNVI 107
                    222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (229 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       464  (0.0258799); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.37u 0.21s 00:00:00.57 Elapsed: 00:00:00.41
# Mc/sec: 1688.44
//
Query:       EEA19718.1  [L=962]
Description: alpha,alpha-trehalose-phosphate synthase subunit Tps2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.4e-148  495.5   0.0     2e-148  495.0   0.0    1.1  1  Glyco_transf_20  Glycosyltransferase family 20
    2.2e-82  275.7   0.0    7.5e-82  274.0   0.0    1.8  2  Trehalose_PPase  Trehalose-phosphatase
  ------ inclusion threshold ------
      0.017   14.8   0.0          1    9.0   0.0    2.2  2  Hydrolase_3      haloacid dehalogenase-like hydrolase


Domain annotation for each model (and alignments):
>> Glyco_transf_20  Glycosyltransferase family 20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  495.0   0.0  3.4e-152    2e-148      88     472 ..     290     673 ..     246     675 .. 0.95

  Alignments for each domain:
  == domain 1  score: 495.0 bits;  conditional E-value: 3.4e-152
                      HHHCCCHHHHCHHHHHTT-GG....G----HHHHHHHHHHHHHHHHHHHCC--TT-EEEEESGGGTTHHHHHHHCCTTSEEEEEE-S----HHH CS
  Glyco_transf_20  88 eeyyngfsksvLWpllHYklpdsseekefersawdaYvkvnklFAdkiveeikdgdliwvhDYhLmllPellRkkledakigfflHiPFPssei 181
                      ++ ++ ++++ L+pllHYk +  + + + er++w +Y+++n+lFAd+i+++++ gd++w+hDYhL+llP+llR++++++ igfflH+PFPsse+
       EEA19718.1 290 QSRWRRYAERELYPLLHYKQN-GPSDGRSERKWWTDYMRLNRLFADRIARIYQAGDIVWIHDYHLFLLPSLLRQRIPNIFIGFFLHSPFPSSEY 382
                      567889**************9.9999******************************************************************** PP

                      HTTSTTHHHHHHHHTTSSEEEESSHHHHHHHHHHHHHHSSEEEECTTEEEEETTEEEEEEE------HHHHHHHC.CSCHHHHHHHHHHHHT.T CS
  Glyco_transf_20 182 friLpvreeilegllgadliGFhtedyarhFlsccsrllgleveskrggveykgrkvsvkalpigidverlesal.kkesvsekvkelkerfen 274
                       r+L++r+e+l+g+lga++iGF+t++y rhF scc+r+lg e +    gv+++g +v v++++ gid +++++a+  +  ++e v+++k+ + +
       EEA19718.1 383 MRCLAKRKEVLTGVLGANMIGFQTYSYSRHFSSCCTRVLGFESNAA--GVDAYGAHVAVDVFATGIDAQNVQKAAfGSSGIEEVVANIKKLYAG 474
                      ***************************************9998888..8**********************9987257779***********99 PP

                      TSEEEEEEEEC-GGG-HHHHHHHHHHHHHH-GGGTTTEEEEEEEEB-STTSHH...HHHHHHHHHHHHHHHHHHH-BTTB-SEEEEES---HHH CS
  Glyco_transf_20 275 kkklilgvDrlDyikGvkqkllaferfLeeypelrgkvvlvqiavpsredvee...yqelekeveelvgrINgefgtldytPvvylersldfee 365
                      k k+i+g+DrlD+++Gv qkl+afe fLe+yp++r++vvl+q+++p++ + ++    +++ ++v+ lv  INg+fg+l++tPv+y+ + +++++
       EEA19718.1 475 K-KIIVGRDRLDSVRGVAQKLQAFEAFLEKYPHWRDQVVLIQVTSPTSMEEQKedpENKIGSQVSSLVSTINGRFGSLSFTPVQYYPQYISQQD 567
                      6.*******************************************9875554323478999********************************* PP

                      HHHHHHH-SEEEE--SSBSS-CHHHHHHHCSTTT--EEEEETTBGGGGT-TTTSEEE-TT-HHHHHHHHHHHHC--HHHHHHHHHHHHHHHHHT CS
  Glyco_transf_20 366 liallaaadvllvtslRdGmnlvakeyvvcqqekkgvLiLSeFaGaaqsLkdaailvNPwdieevaeaikeaLkmseeerkkrekkllkqvskh 459
                      ++ ll++adv l+ts+RdGmn++++eyv cqq+++g+LiLSeF+G+a++L++ ai +NPwd++ va ai++aL+ms ee+ +r+   +k+v+++
       EEA19718.1 568 YFCLLRVADVGLITSVRDGMNTTSLEYVLCQQGNHGPLILSEFSGTAAMLTS-AIHINPWDTTGVATAIDQALSMSAEEKLERHDVAYKHVTSN 660
                      ***************************************************6.6**************************************** PP

                      -HHHHHHHHHHHH CS
  Glyco_transf_20 460 dvqsWaesflsel 472
                      +v+ W ++f+++l
       EEA19718.1 661 TVSMWSQHFINRL 673
                      **********987 PP

>> Trehalose_PPase  Trehalose-phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0      0.15   9.2e+02     127     182 ..     456     510 ..     434     543 .. 0.69
   2 !  274.0   0.0   1.3e-85   7.5e-82       1     229 [.     707     939 ..     707     943 .. 0.94

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.15
                      .THHHHHHHHHHHHHHH.--EEEE-SSEEEEE-S---HHHHHHHHHHTS------- CS
  Trehalose_PPase 127 lqakelaehlesvltdkpdlevtqgkkvvevrpqgvsKGkaverlleslgsadsed 182
                      +  ++++e + ++ + +++ ++ +g++ +     ++ K++a e++le++++   ++
       EEA19718.1 456 FGSSGIEEVVANIKKLYAGKKIIVGRDRLDSVRGVAQKLQAFEAFLEKYPHW-RDQ 510
                      5555566666666666666666666666643333344999999**9999997.333 PP

  == domain 2  score: 274.0 bits;  conditional E-value: 1.3e-85
                      EEETBTTTB---SSGGG--B-TTHHHHHHHHHTTS-..EEEE-SS-HHH.HHHHH---SSEEEEGGGTEEE-TT--EEE-HHHHTTHHHHHHHH CS
  Trehalose_PPase   1 flDydGTlspivedpdaavpssellslLkkLasdpknvvaivSGrslke.eellvkvpelglaaeHGaeirspsgedwenqaevedlewlkevk 93 
                      ++DydGTl+piv+dp+aa+ps+++l+ +k La+dp+n v+i+SGr++++  e+++ +pelgl+aeHG++ir+p ++dwen a++ ++ew+k+v 
       EEA19718.1 707 MFDYDGTLTPIVKDPQAAIPSDRVLRNIKSLAADPRNSVWIISGRDQAFlDEWMGHIPELGLSAEHGCFIRKPRSDDWENLAAKFNMEWQKDVM 800
                      79******************************************************************************************** PP

                      HHHHHHHTTSTT-EEEEETTEEEEE-TT--TT....THHHHHHHHHHHHHHH.--EEEE-SSEEEEE-S---HHHHHHHHHHTS---.-----E CS
  Trehalose_PPase  94 eileektertpGsyiEekkfalsvHyrnadde..elqakelaehlesvltdkpdlevtqgkkvvevrpqgvsKGkaverlleslgsa.dseddf 184
                      ++++++tert+Gs+iE+k++al++Hyr+ad+e  ++qake+ +hle+++ +k+d+ev++gk+++evrp++v+KG +v+rll+++g   + +++f
       EEA19718.1 801 DVFQHYTERTQGSFIERKRVALTWHYRRADPEygAFQAKECRKHLENTVMKKFDVEVMTGKANLEVRPTFVNKGFIVTRLLNEYGRGpGDAPEF 894
                      *************************************************************************************999****** PP

                      EEEEE-SSTTHHHHTTS-TT...-EEEEE--TTS..---EES-SEEE CS
  Trehalose_PPase 185 vlciGDdrtDedmFsvlrktkesgvsievsavev..gskpskakysl 229
                      ++c GDd+tDedmF++lr+      +  +++v+v  +sk++ a + l
       EEA19718.1 895 IFCSGDDFTDEDMFRALRHS--DLPPEHIFSVTVgaSSKQTLAGWHL 939
                      *******************9..5555555555553334666666665 PP

>> Hydrolase_3  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0    0.0086        52       2      94 ..     707     806 ..     706     829 .. 0.70
   2 ?    9.0   0.0   0.00017         1     153     224 ..     837     913 ..     832     915 .. 0.81

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.0086
                  EEEIIIIIS-....TTS---.HHHHHHHHHHHH.TTSEEEEE-SS-HHHHHHHHHHCCCCSEEEEGGGTEE...ECTTTEEEEE--B-HHHHHHHHHH CS
  Hydrolase_3   2 alDlDGTLln....sdkkis.ektkeaikklke.kgikvviATGRslravlpvleelgldlpvialNGali...ddekgkilykstiskedvkeiikl 90 
                  ++D DGTL       +  i+ ++  + ik l +     v i +GR   ++ + + ++  +l + a +G++i   +  +++ l + +++ e  k++++ 
   EEA19718.1 707 MFDYDGTLTPivkdPQAAIPsDRVLRNIKSLAAdPRNSVWIISGRDQAFLDEWMGHIP-ELGLSAEHGCFIrkpRSDDWENL-AAKFNMEWQKDVMDV 802
                  79******66664433334449999999998765778999*************99998.789999******87544444444.555554444444444 PP

                  HHHT CS
  Hydrolase_3  91 lken 94 
                  ++++
   EEA19718.1 803 FQHY 806
                  4443 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00017
                  HHHHHHHHHHHHCTTTEEE.EEESTTEEEEEETT-SHHHHHHHHHHHCT--GGG....EEEEESSGGGHHHHHHSSE CS
  Hydrolase_3 153 kldelekelksklnkllti.tssskgyleimpkgvsKgtalkklakelnislee....viafGDgeNDieMLeaagl 224
                  + +e++k+l++ + k++++ + ++k +le+ p  v+Kg  +++l++e++  + +    +   GD+  D  M+ a  +
   EEA19718.1 837 QAKECRKHLENTVMKKFDVeVMTGKANLEVRPTFVNKGFIVTRLLNEYGRGPGDapefIFCSGDDFTDEDMFRALRH 913
                  568999999999999996615678899*********************99765511116667*********998766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (962 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       470  (0.0262145); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.74u 0.32s 00:00:01.06 Elapsed: 00:00:00.51
# Mc/sec: 5706.82
//
Query:       EEA19719.1  [L=162]
Description: hypothetical protein PMAA_004970 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (162 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       283  (0.0157845); expected 358.6 (0.02)
Passed bias filter:                      256  (0.0142785); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.35u 0.24s 00:00:00.59 Elapsed: 00:00:00.40
# Mc/sec: 1220.12
//
Query:       EEA19720.1  [L=118]
Description: hypothetical protein PMAA_004970 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (118 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       200  (0.0111551); expected 358.6 (0.02)
Passed bias filter:                      186  (0.0103743); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.29u 0.21s 00:00:00.50 Elapsed: 00:00:00.38
# Mc/sec: 920.53
//
Query:       EEA19721.1  [L=236]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.6e-08   32.0   0.0    1.1e-07   31.4   0.0    1.2  1  Macro_2   Macro-like domain


Domain annotation for each model (and alignments):
>> Macro_2  Macro-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.4   0.0   6.4e-12   1.1e-07      65     214 ..      48     205 ..       6     214 .. 0.68

  Alignments for each domain:
  == domain 1  score: 31.4 bits;  conditional E-value: 6.4e-12
     Macro_2  65 hsgekyaivspGnsfGylGGGfdlalfeyfG.....Gkpfetwfrkklgnryytv...Gsatvidltrcllediielrdgiryiihvptvvapsksifq 155
                 ++++   +vsp ns+G l GGfd a+   f       + +    ++ l ++++     G++t++ + r l +     r g + +   pt+ +p  + + 
  EEA19721.1  48 NDTKFDLMVSPANSYGILDGGFDDAISRTFClpqhdYRALTNVAQQILYEKWHGFappGTCTLVSMPRELRK---TNRWGCKVLALCPTMRTPGDARWD 143
                 24444579******************9999722111234445556678888886533377788877777666...7899999999************99 PP

     Macro_2 156 kaeklktGyepvfna.mwn....slmsapkdvdgliisGlctGyaGvpaeiscksmafalslym 214
                 ++    + +  + +   wn    s  +a +++d+++i+ l tG  Gv  e     + f l+l +
  EEA19721.1 144 REVVYECVWSLMCEIdRWNksvsSSSHAESKIDTILITPLATGTGGVSREKWA--LQFVLALKH 205
                 9877666665554322477422255678889****************987544..444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (236 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       373  (0.0208043); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.37u 0.21s 00:00:00.57 Elapsed: 00:00:00.42
# Mc/sec: 1694.69
//
Query:       EEA19722.1  [L=535]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
      0.057   13.6   0.0       0.65   10.2   0.0    2.4  1  PAP_assoc  Cid1 family poly A polymerase
       0.14   12.4   0.4        3.8    7.7   0.3    2.3  2  DUF1823    Domain of unknown function (DUF1823)


Domain annotation for each model (and alignments):
>> PAP_assoc  Cid1 family poly A polymerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   7.3e-05      0.65       2      58 ..     383     470 ..     382     472 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 7.3e-05
                 HHHHHHHHHHHHHHT--TTTEEEECSST-EEEHHHHCGCS-...............................SSEECESSSSEBEETT CS
   PAP_assoc   2 LGeLLigFFeyYgreFdyenvvisirtggiltkkekgwesa...............................eskernrfllaIeDPf 58 
                 L+e L+++++ Yg++ d ++++is ++ +++t ++ +                                   + ++    +l+I+DP 
  EEA19722.1 383 LAEQLLALLHTYGEQIDLTTTGISASPAEFFTGRSVRDRIRslnksgsnnsqlpdylrgqrglmaykihashKGNKGMARHLCIQDPT 470
                 6777999******************998887777776665566667777778899999999999999988887777788889999996 PP

>> DUF1823  Domain of unknown function (DUF1823)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.3   0.00042       3.8       3     108 ..      62     164 ..      60     168 .. 0.85
   2 ?    2.2   0.0     0.023     2e+02      42      67 ..     207     232 ..     192     248 .. 0.79

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00042
                 -HHHHHHHHHT-S-HHHHHHHHHHHHT--EETTTTEE--TTS-HHHHTT-SS---TTT--HHHHHHHHTS-GGGTTHHHHTT------GGG--HHHHHH CS
     DUF1823   3 seetllkileeeisDeevnelvwealgYrydeaeekwdasevapeWreeypeppdliesrpatvkltRsipkenkqllkeklgfkGykideltPrktRR 101
                 +++ l k le + +  + ++lvw++  Y+ d+ +e  + +e +++ +   pep ++ ++++ + ++tRs   + k +  ++++ +  ++  + P +  R
  EEA19722.1  62 NKNSLKKTLEAQRT-VNRERLVWKY--YVRDKPDEGKTGDERTDNAAGVTPEPKNIKKVNNGSREVTRSKKYKPKPSRGKEIEVAHVRLPWVIPLEDGR 157
                 55556666655433.23358***98..888999999999999*********************************999999999999999999999999 PP

                 HHHHHHH CS
     DUF1823 102 ataanwl 108
                 a+   wl
  EEA19722.1 158 AQRNPWL 164
                 9999998 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.023
                 TTS-HHHHTT-SS---TTT--HHHHH CS
     DUF1823  42 sevapeWreeypeppdliesrpatvk 67 
                 ++ +++ ++  p+pp+li+sr a  +
  EEA19722.1 207 DDLSSKIQSIVPNPPQLIGSRYAELA 232
                 56667778889**********88654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (535 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       470  (0.0262145); expected 358.6 (0.02)
Passed bias filter:                      439  (0.0244855); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.29s 00:00:00.89 Elapsed: 00:00:00.49
# Mc/sec: 3255.26
//
Query:       EEA19723.1  [L=371]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.2e-10   38.7   0.1    5.8e-07   29.1   0.1    2.2  1  LETM1     LETM1-like protein


Domain annotation for each model (and alignments):
>> LETM1  LETM1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.1   0.1   3.2e-11   5.8e-07      36     253 ..     162     365 ..     150     369 .. 0.77

  Alignments for each domain:
  == domain 1  score: 29.1 bits;  conditional E-value: 3.2e-11
       LETM1  36 gkeLsrrEreqlkrttaDllrlvPfsvfiivPfaelllpvllklFPnlLpstFeskkqkeeklkkrlkarlevakfLqetleeslkkkkkekkekaeel 134
                   +++r + ++++r+  D+ rl+Pf +++++   e++ +v++ l   + p t   +kq  + + krl+++   +  +q  l +++  + +e++  +++ 
  EEA19723.1 162 TLKITRSDFQLVRRAAYDIRRLIPFGLIFLI-CGEFTPLVVVLLGDAVTPYTCRIPKQLAKTRAKRLEQKGHAFAAVQGGLGSMK--PMREQDVMTWQA 257
                 55699*********************99999.678887777777777**********************************7663..233333344444 PP

       LETM1 135 keflkkvrsggepeevsneeilkvaklFkdeltLdnlsrkqlkalckllslqpfgtdnllryrlrkklreikedDkaikre.GvdsLseeeLqeacrsR 232
                  +f ++        ++s+e++l+ + +F                l+k ++  +   + + r rl+k ++ +  dD++i ++ Gvd Ls +eL+ a  +R
  EEA19723.1 258 LQFGSREFA----ATASAEQVLRACAVFG---------------LAKSHDQGAAWVSLIYRPRLQKWTEYLALDDQLIVQNgGVDYLSAQELKIAIDER 337
                 444433322....235899****999996...............55555555555567889*******************99***************** PP

       LETM1 233 G.lraa......glseeelreqLeqWle 253
                 G +++       g  e++ re+L+ Wl+
  EEA19723.1 338 GgFEPSadvrraGQVEKAEREWLKLWLK 365
                 9423223333335566666777777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (371 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       363  (0.0202465); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.47
# Mc/sec: 2349.16
//
Query:       EEA19724.1  [L=240]
Description: isochorismatase family hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.2e-16   61.4   0.0    5.1e-16   59.3   0.0    1.8  1  Isochorismatase  Isochorismatase family


Domain annotation for each model (and alignments):
>> Isochorismatase  Isochorismatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.3   0.0   2.9e-20   5.1e-16       1     174 [.      18     230 ..      18     231 .. 0.82

  Alignments for each domain:
  == domain 1  score: 59.3 bits;  conditional E-value: 2.9e-20
  Isochorismatase   1 talvviDmqndfv....eegvkeseeisavveninkllkaarkag............ipviftrdvheleevkgdlderkaaphfkpgttgael 78 
                      +alv+iD q  f     ++  +     + + +n   ll+a+r+a+            i+v+++                ++++    +t g + 
       EEA19724.1  18 SALVLIDNQAAFKhpthWGSSR---SNPSFEQNLTSLLEAFRTARqrswsstapiyiIHVFHSSL-------------SPDSKLHSSNTDGIKP 95 
                      69***********744433333...3444445666666666666655566654433333333333.............5557777888888888 PP

  Isochorismatase  79 vpelaple..gdvvvdKtrfsafagtdldeiLkelgiktivlaGiatdvCVeatardaldlGy............................... 139
                      ++   p +  +++v+ K+  s+f gt+l+ +L+e+g++++ +aG++td CV +t+r a++l +                               
       EEA19724.1  96 LDFAVPAAdgSEPVFWKSVNSSFIGTGLESFLREHGVRQVFFAGLTTDHCVSTTTRMAANLHVvdrissqgkqtdkvtvnpdgslpegvsidhg 189
                      88888888889*********************************************************************************** PP

  Isochorismatase 140 evvvvsDAvaals.....pel.hdaalkrlkqafatvitte 174
                      +vv+v+DA+a++      +e+ h+ ++++l + fa+v +t 
       EEA19724.1 190 RVVLVADATATFAkggfdAETiHAVSVASLGEEFADVFSTR 230
                      **********999888887777999999999****999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (240 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       387  (0.0215851); expected 358.6 (0.02)
Passed bias filter:                      344  (0.0191868); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.31s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 1631.47
//
Query:       EEA19725.1  [L=316]
Description: nicotinate-nucleotide pyrophosphorylase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.9e-48  164.4   0.2    1.7e-46  158.1   0.2    2.1  1  QRPTase_C  Quinolinate phosphoribosyl transferase, C-terminal
    7.7e-23   80.4   0.2    5.7e-22   77.6   0.0    2.4  2  QRPTase_N  Quinolinate phosphoribosyl transferase, N-terminal
  ------ inclusion threshold ------
      0.024   14.0   0.1      0.039   13.3   0.1    1.3  1  TMP-TENI   Thiamine monophosphate synthase


Domain annotation for each model (and alignments):
>> QRPTase_C  Quinolinate phosphoribosyl transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  158.1   0.2   2.9e-50   1.7e-46       1     169 []     115     312 ..     115     312 .. 0.97

  Alignments for each domain:
  == domain 1  score: 158.1 bits;  conditional E-value: 2.9e-50
                 HHHHHHHHHHHHHCT..SSEEEE-S---TTTHHHHHHHHHHTTSB--TSSTTTSEEE-HHHHHHHSS....................HHHHHHHHHHHH CS
   QRPTase_C   1 iAtltarmveaaksa..kvrildTRkttPglrllekyAvliGGgdnhrlgLsdmvlikdnhiaaags....................iveavksvreav 77 
                 iAt+t+++v+ ++s+  + ++++TRkttPg+rl+eky +liGG+d hr +Ls+m+++kdnh++a+ +                    i  av+++++a 
  EEA19725.1 115 IATKTSSLVQILRSHgwNGTLAGTRKTTPGFRLVEKYGILIGGADPHRHDLSSMIMLKDNHVWACANnvsntasaaegvsedaiaaaIPAAVQAAKSAG 213
                 9**************************************************************99999999***********99999999999999999 PP

                 TTTSEEEEEESSHHHHHHHHHHT-SEEEEES--HHHHHHHHHHHHHHSTT.......SEEEEESS--TTTHHHHHCTT-SEEEECHHCHTB----EEEE CS
   QRPTase_C  78 dkevkievevesleeleevleaeadiimLDnfsveelkkaveelkeknkr.......vlievSGgvtlenveeyaksgvdvisvgalthsvkalDislk 169
                 ++  k+evev+s ee++++++a+ad+imLDnf+++e+kka+ +lk  + +       +l+evSGg+t +n + + +++vd++s++++++++  +D+slk
  EEA19725.1 214 GFSTKVEVEVRSIEEANAAISAGADVIMLDNFTADEVKKAAAQLKTEWAEkgkprgtFLVEVSGGLTPDNAAGFVCEDVDILSTSSIHQGTGIVDFSLK 312
                 ******************************************9977776668899******************************************97 PP

>> QRPTase_N  Quinolinate phosphoribosyl transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.6   0.0   9.5e-26   5.7e-22      12      89 .]      37     113 ..      28     113 .. 0.96
   2 ?   -0.4   0.1      0.21   1.3e+03      25      51 ..     194     222 ..     180     240 .. 0.73

  Alignments for each domain:
  == domain 1  score: 77.6 bits;  conditional E-value: 9.5e-26
                 GCTTSEEEEEEEESSSEEE-SHHHHHHHHHHHTTTEEEESS-TT-EEETTEEEEEEEEEHHHHHHHHHHHHHHHHHHH CS
   QRPTase_N  12 ipeekkakaeiiakeegvvaGlevaeevfellpglevellvkDGervekgdvlleieGnarallsaERvaLnllqrlS 89 
                 + +e +++a+++ k++gvvaG+++++evf++l g++ve++v++Ge++++ + +++++G++r++l +ERvaLn+l r+S
  EEA19725.1  37 VVGESEGEARLLGKSAGVVAGVPFFNEVFSQL-GCSVEWHVSEGESITPIKQCATVRGPVRKILLGERVALNILARCS 113
                 678999**************************.*******************************************98 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.21
                 SSSEEE-SHHHHHHHHHHH..TTTEEEES CS
   QRPTase_N  25 keegvvaGlevaeevfell..pglevell 51 
                  e+++ a +++a +  + +   +++ve++
  EEA19725.1 194 SEDAIAAAIPAAVQAAKSAggFSTKVEVE 222
                 58899999999999999886633344443 PP

>> TMP-TENI  Thiamine monophosphate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.1   6.6e-06     0.039     101     171 ..     221     291 ..     203     299 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 6.6e-06
    TMP-TENI 101 lSvhsleeaeeaealgadYigvGpifpTdtKkdaeplgleglkelaealeiPvvaiGGitlenvaevleag 171
                 + v s+eea++a ++gad i++  + + + Kk a+ l  e +++ + + +  v + GG+t++n+a  +   
  EEA19725.1 221 VEVRSIEEANAAISAGADVIMLDNFTADEVKKAAAQLKTEWAEKGKPRGTFLVEVSGGLTPDNAAGFVCED 291
                 557899*********************************************************98766555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (316 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       593  (0.0330749); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2208.96
//
Query:       EEA19726.1  [L=316]
Description: nicotinate-nucleotide pyrophosphorylase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.9e-48  164.4   0.2    1.7e-46  158.1   0.2    2.1  1  QRPTase_C  Quinolinate phosphoribosyl transferase, C-terminal
    7.7e-23   80.4   0.2    5.7e-22   77.6   0.0    2.4  2  QRPTase_N  Quinolinate phosphoribosyl transferase, N-terminal
  ------ inclusion threshold ------
      0.024   14.0   0.1      0.039   13.3   0.1    1.3  1  TMP-TENI   Thiamine monophosphate synthase


Domain annotation for each model (and alignments):
>> QRPTase_C  Quinolinate phosphoribosyl transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  158.1   0.2   2.9e-50   1.7e-46       1     169 []     115     312 ..     115     312 .. 0.97

  Alignments for each domain:
  == domain 1  score: 158.1 bits;  conditional E-value: 2.9e-50
                 HHHHHHHHHHHHHCT..SSEEEE-S---TTTHHHHHHHHHHTTSB--TSSTTTSEEE-HHHHHHHSS....................HHHHHHHHHHHH CS
   QRPTase_C   1 iAtltarmveaaksa..kvrildTRkttPglrllekyAvliGGgdnhrlgLsdmvlikdnhiaaags....................iveavksvreav 77 
                 iAt+t+++v+ ++s+  + ++++TRkttPg+rl+eky +liGG+d hr +Ls+m+++kdnh++a+ +                    i  av+++++a 
  EEA19726.1 115 IATKTSSLVQILRSHgwNGTLAGTRKTTPGFRLVEKYGILIGGADPHRHDLSSMIMLKDNHVWACANnvsntasaaegvsedaiaaaIPAAVQAAKSAG 213
                 9**************************************************************99999999***********99999999999999999 PP

                 TTTSEEEEEESSHHHHHHHHHHT-SEEEEES--HHHHHHHHHHHHHHSTT.......SEEEEESS--TTTHHHHHCTT-SEEEECHHCHTB----EEEE CS
   QRPTase_C  78 dkevkievevesleeleevleaeadiimLDnfsveelkkaveelkeknkr.......vlievSGgvtlenveeyaksgvdvisvgalthsvkalDislk 169
                 ++  k+evev+s ee++++++a+ad+imLDnf+++e+kka+ +lk  + +       +l+evSGg+t +n + + +++vd++s++++++++  +D+slk
  EEA19726.1 214 GFSTKVEVEVRSIEEANAAISAGADVIMLDNFTADEVKKAAAQLKTEWAEkgkprgtFLVEVSGGLTPDNAAGFVCEDVDILSTSSIHQGTGIVDFSLK 312
                 ******************************************9977776668899******************************************97 PP

>> QRPTase_N  Quinolinate phosphoribosyl transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.6   0.0   9.5e-26   5.7e-22      12      89 .]      37     113 ..      28     113 .. 0.96
   2 ?   -0.4   0.1      0.21   1.3e+03      25      51 ..     194     222 ..     180     240 .. 0.73

  Alignments for each domain:
  == domain 1  score: 77.6 bits;  conditional E-value: 9.5e-26
                 GCTTSEEEEEEEESSSEEE-SHHHHHHHHHHHTTTEEEESS-TT-EEETTEEEEEEEEEHHHHHHHHHHHHHHHHHHH CS
   QRPTase_N  12 ipeekkakaeiiakeegvvaGlevaeevfellpglevellvkDGervekgdvlleieGnarallsaERvaLnllqrlS 89 
                 + +e +++a+++ k++gvvaG+++++evf++l g++ve++v++Ge++++ + +++++G++r++l +ERvaLn+l r+S
  EEA19726.1  37 VVGESEGEARLLGKSAGVVAGVPFFNEVFSQL-GCSVEWHVSEGESITPIKQCATVRGPVRKILLGERVALNILARCS 113
                 678999**************************.*******************************************98 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.21
                 SSSEEE-SHHHHHHHHHHH..TTTEEEES CS
   QRPTase_N  25 keegvvaGlevaeevfell..pglevell 51 
                  e+++ a +++a +  + +   +++ve++
  EEA19726.1 194 SEDAIAAAIPAAVQAAKSAggFSTKVEVE 222
                 58899999999999999886633344443 PP

>> TMP-TENI  Thiamine monophosphate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.1   6.6e-06     0.039     101     171 ..     221     291 ..     203     299 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 6.6e-06
    TMP-TENI 101 lSvhsleeaeeaealgadYigvGpifpTdtKkdaeplgleglkelaealeiPvvaiGGitlenvaevleag 171
                 + v s+eea++a ++gad i++  + + + Kk a+ l  e +++ + + +  v + GG+t++n+a  +   
  EEA19726.1 221 VEVRSIEEANAAISAGADVIMLDNFTADEVKKAAAQLKTEWAEKGKPRGTFLVEVSGGLTPDNAAGFVCED 291
                 557899*********************************************************98766555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (316 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       593  (0.0330749); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.51
# Mc/sec: 1876.20
//
Query:       EEA19727.1  [L=1499]
Description: anucleate primary sterigmata (ApsB), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.7e-23   80.6  11.3    6.7e-23   80.6  11.3   11.7 12  Cnn_1N          Centrosomin N-terminal motif 1
    2.5e-15   56.5  19.6    2.5e-15   56.5  19.6   11.4 14  Mto2_bdg        Micro-tubular organiser Mto1 C-term Mto2-bind
    0.00059   20.0   8.2    0.00059   20.0   8.2    7.2  8  Fib_alpha       Fibrinogen alpha/beta chain family
     0.0048   17.8   0.4     0.0048   17.8   0.4   12.5 13  PRKG1_interact  cGMP-dependent protein kinase interacting dom
  ------ inclusion threshold ------
       0.28   11.5   2.9        7.6    6.9   0.3    4.2  2  DUF2935         Domain of unknown function (DUF2935)


Domain annotation for each model (and alignments):
>> Cnn_1N  Centrosomin N-terminal motif 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.6  11.3   1.9e-26   6.7e-23       1      72 [.     453     524 ..     453     525 .. 0.99
   2 ?   -1.9   1.0       1.1   3.9e+03      41      64 ..     551     574 ..     537     584 .. 0.69
   3 ?    1.4   0.3     0.099   3.5e+02      33      58 ..     618     643 ..     608     646 .. 0.83
   4 ?    2.8   0.6     0.036   1.3e+02       9      52 ..     691     733 ..     687     743 .. 0.73
   5 !    8.2   0.9   0.00076       2.7      32      70 ..     769     807 ..     762     816 .. 0.83
   6 ?    3.2   7.3     0.027        98       4      71 ..     784     854 ..     784     856 .. 0.85
   7 ?   -2.1   5.1       1.2   4.5e+03      29      66 ..     837     874 ..     823     880 .. 0.67
   8 ?   -1.9   5.5       1.1   3.8e+03      35      69 ..     900     940 ..     879     959 .. 0.54
   9 ?   -4.4   7.6         5   1.8e+04      24      70 ..     994    1040 ..     955    1049 .. 0.54
  10 !    5.0   1.4    0.0074        27      23      70 ..    1057    1107 ..    1048    1110 .. 0.79
  11 ?   -3.0   1.0       2.3   8.3e+03      16      60 ..    1144    1188 ..    1133    1194 .. 0.60
  12 ?    0.2   4.0      0.24   8.5e+02      22      63 ..    1388    1432 ..    1387    1438 .. 0.89

  Alignments for each domain:
  == domain 1  score: 80.6 bits;  conditional E-value: 1.9e-26
      Cnn_1N   1 TlrEqeeqidkLkKENFdLKLriyfLeerleklseeqkeellkenielkveveslqkelkekkkllreaeka 72 
                 Tl+Eq+++id+L+KENFdLK+ri+fL+e+l+k+see ++e+++en+elk +  +lqke++ +k+ +r++ek+
  EEA19727.1 453 TLKEQSSTIDRLSKENFDLKMRIHFLNEALNKRSEEGIKEMISENVELKSDKIKLQKENQGMKRTIRNLEKQ 524
                 9*********************************************************************97 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 1.1
      Cnn_1N  41 llkenielkveveslqkelkekkk 64 
                  ++e+i l++++e+ + e+++++ 
  EEA19727.1 551 EEEELIFLRERIETYEVEIERLRT 574
                 456788899999999999988765 PP

  == domain 3  score: 1.4 bits;  conditional E-value: 0.099
      Cnn_1N  33 lseeqkeellkenielkveveslqke 58 
                  ++  +e++++en +l++e+  ++ e
  EEA19727.1 618 AETAAREQAEDENRKLRDEILRMKAE 643
                 4557899*************999876 PP

  == domain 4  score: 2.8 bits;  conditional E-value: 0.036
      Cnn_1N   9 idkLkKENFdLKLriyfLeerleklseeqkeellkenielkvev 52 
                 i+ LkKEN  L+ ++    + l+ ++  +ke l +e  +lk ++
  EEA19727.1 691 IELLKKENAELRREVSVQTSMLTSRNR-EKERLYQEIEDLKLQR 733
                 677888888888888777776666665.7788888877777766 PP

  == domain 5  score: 8.2 bits;  conditional E-value: 0.00076
      Cnn_1N  32 klseeqkeellkenielkveveslqkelkekkkllreae 70 
                 +ls++++e+l+  n el+++v +l+ e++ ++ +l+e  
  EEA19727.1 769 RLSDTERESLEVRNGELRDQVSTLKLENQGLRSQLDEYT 807
                 566788899999999999999999999999999998865 PP

  == domain 6  score: 3.2 bits;  conditional E-value: 0.027
      Cnn_1N   4 EqeeqidkLkKENFdLKLriyfLeerleklse...eqkeellkenielkveveslqkelkekkkllreaek 71 
                 E+  q+++Lk EN +L+ ++ +   +le+l++    +++++++e+  l++e+ +  +  +e++  l++++ 
  EEA19727.1 784 ELRDQVSTLKLENQGLRSQLDEYTAELEALDKayqADVDQAEEELQILQQERDQALQVAEEREAALQDLKA 854
                 6678999*************777777666666666999****************99999999999999865 PP

  == domain 7  score: -2.1 bits;  conditional E-value: 1.2
      Cnn_1N  29 rleklseeqkeellkenielkveveslqkelkekkkll 66 
                 +  + +ee   +l +   e ++e+ +l +el++k ++ 
  EEA19727.1 837 QALQVAEEREAALQDLKAEAQEEIDTLGDELDQKVEEC 874
                 23334446666777778899999999999999887765 PP

  == domain 8  score: -1.9 bits;  conditional E-value: 1.1
      Cnn_1N  35 e......eqkeellkenielkveveslqkelkekkkllrea 69 
                 e      e+ ++ l++   +++e+e+  +e+++++k l ea
  EEA19727.1 900 EgilrleEDAQSNLRKFKGVQQELEDSNREIESLEKNLFEA 940
                 13333334444444445555666666666666666666555 PP

  == domain 9  score: -4.4 bits;  conditional E-value: 5
      Cnn_1N   24 yfLeerleklseeqkeellkenielkveveslqkelkekkkllreae 70  
                  ++Le rl + + +      ke  e++  + +l +e  + k+++r+++
  EEA19727.1  994 KELETRLAEERHQREVVGSKEKQEVQRIMNDLNREASAAKDEIRRLK 1040
                  45555555555533333334444444444444444444444444444 PP

  == domain 10  score: 5.0 bits;  conditional E-value: 0.0074
      Cnn_1N   23 iyfLeerleklse...eqkeellkenielkveveslqkelkekkkllreae 70  
                  +++Le+ l +       ++ +ll++ i+l+ e+es   +l++ + +l+e e
  EEA19727.1 1057 LMELENGLREALGdlnGTRSSLLNSIIKLQKELESKSLDLESTRSKLDEKE 1107
                  4445554444333566799****************************9976 PP

  == domain 11  score: -3.0 bits;  conditional E-value: 2.3
      Cnn_1N   16 NFdLKLriyfLeerleklseeqkeellkenielkveveslqkelk 60  
                   Fd  L+ +   +r    +++ + +l++ + + + + +sl+++lk
  EEA19727.1 1144 SFDQALKSQQQASRTISQHNSRISDLESARSQDRKRYASLEQQLK 1188
                  555555555555555555556666666666666666666666665 PP

  == domain 12  score: 0.2 bits;  conditional E-value: 0.24
      Cnn_1N   22 riyfLeerleklse...eqkeellkenielkveveslqkelkekk 63  
                  r+ +Le rl++ ++    +++ + k + +   e+e+l+ el++ +
  EEA19727.1 1388 RLRELERRLKNERTarlADRDGARKRLEQRDAENEELRAELERER 1432
                  677899999999999999999*******************99865 PP

>> Mto2_bdg  Micro-tubular organiser Mto1 C-term Mto2-binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0         5   1.8e+04      31      43 ..     461     473 ..     459     476 .. 0.79
   2 ?   -3.0   0.2       2.7   9.5e+03      31      51 ..     490     511 ..     487     512 .. 0.71
   3 ?    1.8   0.2     0.087   3.1e+02       6      19 ..     518     532 ..     514     549 .. 0.75
   4 ?   -0.4   0.7      0.42   1.5e+03      33      49 ..     625     641 ..     619     643 .. 0.79
   5 !    5.3   0.1    0.0068        24      18      48 ..     675     708 ..     669     711 .. 0.69
   6 ?   -0.2   0.5      0.35   1.2e+03      27      46 ..     785     804 ..     767     807 .. 0.77
   7 ?   -3.0   0.2       2.7   9.8e+03      16      32 ..     844     861 ..     839     866 .. 0.63
   8 ?   -1.3   0.9      0.78   2.8e+03      20      45 ..     912     937 ..     904     940 .. 0.80
   9 ?   -0.9   1.0      0.58   2.1e+03       7      20 ..     994    1007 ..     971    1017 .. 0.76
  10 ?   -0.1   0.6      0.32   1.1e+03      11      35 ..    1037    1061 ..    1033    1076 .. 0.72
  11 ?   -0.6   0.4      0.49   1.7e+03      12      35 ..    1084    1107 ..    1082    1109 .. 0.90
  12 ?    1.2   0.6      0.13   4.6e+02      14      36 ..    1132    1154 ..    1126    1167 .. 0.83
  13 ?   -3.1   0.2       2.9     1e+04       7      15 ..    1181    1189 ..    1178    1196 .. 0.67
  14 !   56.5  19.6     7e-19   2.5e-15       3      52 .]    1386    1435 ..    1384    1435 .. 0.97

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 5
    Mto2_bdg  31 LeelkaeNrlLka 43 
                 ++ l +eN +Lk 
  EEA19727.1 461 IDRLSKENFDLKM 473
                 6778999999986 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 2.7
    Mto2_bdg  31 LeelkaeNrlLka.eLerdrsh 51 
                 ++e + eN +Lk  ++++++++
  EEA19727.1 490 IKEMISENVELKSdKIKLQKEN 511
                 6778889999986357777765 PP

  == domain 3  score: 1.8 bits;  conditional E-value: 0.087
    Mto2_bdg   6 LreLerqLkaer.ea 19 
                 +r Le+qLk ++  +
  EEA19727.1 518 IRNLEKQLKDSQsNK 532
                 589********9444 PP

  == domain 4  score: -0.4 bits;  conditional E-value: 0.42
    Mto2_bdg  33 elkaeNrlLkaeLerdr 49 
                 + + eNr+L+ e+ r +
  EEA19727.1 625 QAEDENRKLRDEILRMK 641
                 55789*****9997766 PP

  == domain 5  score: 5.3 bits;  conditional E-value: 0.0068
    Mto2_bdg  18 eaRlldrsgare...rLeelkaeNrlLkaeLerd 48 
                 ++Rl+ +s+      ++e lk+eN++L++e + +
  EEA19727.1 675 DRRLTVPSSTGStlvEIELLKKENAELRREVSVQ 708
                 5566666665432227899**********98765 PP

  == domain 6  score: -0.2 bits;  conditional E-value: 0.35
    Mto2_bdg  27 arerLeelkaeNrlLkaeLe 46 
                  r   + lk eN+ L+ +L 
  EEA19727.1 785 LRDQVSTLKLENQGLRSQLD 804
                 46777889999999999985 PP

  == domain 7  score: -3.0 bits;  conditional E-value: 2.7
    Mto2_bdg  16 ereaRlld.rsgarerLe 32 
                 erea+l d +  a+e+++
  EEA19727.1 844 EREAALQDlKAEAQEEID 861
                 778888773334666666 PP

  == domain 8  score: -1.3 bits;  conditional E-value: 0.78
    Mto2_bdg  20 RlldrsgarerLeelkaeNrlLkaeL 45 
                  l+  +g++++Le+ ++e ++L+ +L
  EEA19727.1 912 NLRKFKGVQQELEDSNREIESLEKNL 937
                 56667899*********999998766 PP

  == domain 9  score: -0.9 bits;  conditional E-value: 0.58
    Mto2_bdg    7 reLerqLkaereaR 20  
                  +eLe +L  er +R
  EEA19727.1  994 KELETRLAEERHQR 1007
                  57777777777555 PP

  == domain 10  score: -0.1 bits;  conditional E-value: 0.32
    Mto2_bdg   11 rqLkaereaRlldrsgarerLeelk 35  
                  r+Lk    aR  d    +erL el+
  EEA19727.1 1037 RRLKKTLSAREIDAATWKERLMELE 1061
                  6666666677777777777776664 PP

  == domain 11  score: -0.6 bits;  conditional E-value: 0.49
    Mto2_bdg   12 qLkaereaRlldrsgarerLeelk 35  
                  +L+ e e  +ld ++ r +L+e++
  EEA19727.1 1084 KLQKELESKSLDLESTRSKLDEKE 1107
                  5889999**************985 PP

  == domain 12  score: 1.2 bits;  conditional E-value: 0.13
    Mto2_bdg   14 kaereaRlldrsgarerLeelka 36  
                    er+aR+ d+ +  + L+ +++
  EEA19727.1 1132 DRERQARRADKHSFDQALKSQQQ 1154
                  569********999888877765 PP

  == domain 13  score: -3.1 bits;  conditional E-value: 2.9
    Mto2_bdg    7 reLerqLka 15  
                    Le+qLk 
  EEA19727.1 1181 ASLEQQLKD 1189
                  568999995 PP

  == domain 14  score: 56.5 bits;  conditional E-value: 7e-19
    Mto2_bdg    3 leRLreLerqLkaereaRlldrsgarerLeelkaeNrlLkaeLerdrshs 52  
                  ++RLreLer+Lk+er aRl dr gar+rLe+++aeN++L+aeLer+r+++
  EEA19727.1 1386 IQRLRELERRLKNERTARLADRDGARKRLEQRDAENEELRAELERERMRR 1435
                  89**********************************************85 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   6.2     0.041   1.5e+02      46     123 ..     506     574 ..     478     592 .. 0.49
   2 !   20.0   8.2   1.7e-07   0.00059      26     130 ..     810     914 ..     805     919 .. 0.92
   3 ?    1.8   0.6     0.071   2.5e+02      84     128 ..     911     954 ..     907     959 .. 0.78
   4 ?    2.0   5.8      0.06   2.2e+02      25     117 ..     960    1049 ..     957    1063 .. 0.84
   5 ?    3.2   3.7     0.026        92      38     129 ..    1016    1107 ..    1005    1109 .. 0.87
   6 ?    2.1   3.7     0.057     2e+02      25      88 ..    1130    1193 ..    1125    1201 .. 0.60
   7 ?   -3.5   0.1         3   1.1e+04      54      70 ..    1257    1273 ..    1245    1291 .. 0.44
   8 ?   -2.4   0.4       1.4   4.9e+03      55      89 ..    1361    1395 ..    1355    1402 .. 0.63

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.041
                 CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  46 eisnstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvLqnvlesneqkiqkLeq 123
                 +++++++ +++++++++++l++ q++k++ d+  + s         + +++ d +e+++ +L++ +e+ e++i++L++
  EEA19727.1 506 KLQKENQGMKRTIRNLEKQLKDSQSNKSGVDTEGETS---------EDDKRNDVEEEELIFLRERIETYEVEIERLRT 574
                 4455555555555555555555555554432222222.........22222222333333333333333333333333 PP

  == domain 2  score: 20.0 bits;  conditional E-value: 1.7e-07
                 CCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  26 llkyekdvkkdlekleneleeisnstkeaeelvkeikdslrekqkskkdn.dnvikksskeleeeilrlketidaqesnirvLqnvlesneqkiqkLeq 123
                 l+  +k ++ d+++ e+el+ ++++  +a ++ +e +  l++ +++++++ d++  ++ +++e e +r++ t+ +qe+n++ Lq  ++s ++ i +Le+
  EEA19727.1 810 LEALDKAYQADVDQAEEELQILQQERDQALQVAEEREAALQDLKAEAQEEiDTLGDELDQKVE-ECARMELTLRTQEENLKTLQAEMRSASEGILRLEE 907
                 5667888999******************************99999999888************.*********************************** PP

                 HHHHHHH CS
   Fib_alpha 124 didqker 130
                 d ++  r
  EEA19727.1 908 DAQSNLR 914
                 *988766 PP

  == domain 3  score: 1.8 bits;  conditional E-value: 0.071
                 HHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  84 keleeeilrlketidaqesnirvLqnvlesneqkiqkLeqdidqk 128
                 ++l+ +   +++++ +  ++i+ L ++l + + k+q+L ++i++ 
  EEA19727.1 911 SNLR-KFKGVQQELEDSNREIESLEKNLFEANGKVQRLTVQIESS 954
                 5666.6777788888888899999999999999999999888765 PP

  == domain 4  score: 2.0 bits;  conditional E-value: 0.06
                  CCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHH CS
   Fib_alpha   25 lllkyekdvkkdlekleneleeisnstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvLqnvlesneqk 117 
                  +l + +   k ++++l +el+ ++   +  +e +ke+++ l+e+ ++ +    v +k ++e+++ +++l+++ +a   +ir L+++l++ e +
  EEA19727.1  960 FLREEQDADKIRISELDSELKAYRIHLQVEKEKTKELETRLAEERHQRE---VVGSKEKQEVQRIMNDLNREASAAKDEIRRLKKTLSAREID 1049
                  666677777789*****************************99998887...78889999999888899999999999999999999877655 PP

  == domain 5  score: 3.2 bits;  conditional E-value: 0.026
                  CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha   38 ekleneleeisnstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvLqnvlesneqkiqkLeqdidqke 129 
                  +++++ +++++++ + a++ ++++k++l +++  ++  ++ + ++++ l+e   +l+ t ++  ++i +Lq+ les++ +++  +++ d+ke
  EEA19727.1 1016 QEVQRIMNDLNREASAAKDEIRRLKKTLSAREIDAATWKERLMELENGLREALGDLNGTRSSLLNSIIKLQKELESKSLDLESTRSKLDEKE 1107
                  67888999999999999999999999999999999988999999999999999999999999999999999999999988888777777765 PP

  == domain 6  score: 2.1 bits;  conditional E-value: 0.057
                  CCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha   25 lllkyekdvkkdlekleneleeisnstkeaeelvkeikdslrekqkskkdndnvikksskelee 88  
                  ll++ ++  + d ++  + l++ ++ +++++++ ++i+d   ++ +  k   ++ ++++++l e
  EEA19727.1 1130 LLDRERQARRADKHSFDQALKSQQQASRTISQHNSRISDLESARSQDRKRYASLEQQLKDQLSE 1193
                  5555555555555566666666666666666666666666666666666556666666666654 PP

  == domain 7  score: -3.5 bits;  conditional E-value: 3
                  HHHHHHHHHHHHHHHHH CS
   Fib_alpha   54 aeelvkeikdslrekqk 70  
                   ++ +++++  l+++ +
  EEA19727.1 1257 FRTRIRQVERDLTKEYQ 1273
                  23333333322222222 PP

  == domain 8  score: -2.4 bits;  conditional E-value: 1.4
                  HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
   Fib_alpha   55 eelvkeikdslrekqkskkdndnvikksskeleee 89  
                   +lv++ +++  +++ +++++dnv+ +  +ele++
  EEA19727.1 1361 TTLVETSSSTSSQRKPHDSEQDNVMIQRLRELERR 1395
                  44555555555566666666788888888888844 PP

>> PRKG1_interact  cGMP-dependent protein kinase interacting domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.1       1.8   6.5e+03      12      57 ..      90     133 ..      85     160 .. 0.56
   2 ?    3.1   4.7      0.05   1.8e+02      56     101 ..     476     522 ..     448     523 .. 0.60
   3 ?   -0.6  10.8      0.73   2.6e+03       9      82 ..     507     575 ..     491     591 .. 0.44
   4 ?    0.3   9.1      0.37   1.3e+03      16      90 ..     558     644 ..     548     647 .. 0.62
   5 ?    4.7   2.3     0.016        56       7      89 ..     624     704 ..     624     707 .. 0.82
   6 ?    4.8  10.1     0.015        54       6      93 ..     712     799 ..     692     801 .. 0.67
   7 ?  -11.2  22.9         5   1.8e+04      10      84 ..     793     857 ..     781     937 .. 0.58
   8 ?   -4.1  15.2         5   1.8e+04      17      88 ..     920     995 ..     909    1037 .. 0.64
   9 ?   -8.1  13.9         5   1.8e+04      11      56 ..    1013    1062 ..     987    1105 .. 0.61
  10 ?   -6.6  15.6         5   1.8e+04       5      74 ..    1116    1188 ..    1065    1197 .. 0.68
  11 ?   -3.9   0.1         5   1.8e+04      17      37 ..    1258    1278 ..    1252    1292 .. 0.64
  12 !   17.8   0.4   1.3e-06    0.0048       8      92 ..    1318    1402 ..    1311    1405 .. 0.89
  13 ?    1.5   2.3      0.15   5.4e+02       5      44 ..    1413    1438 ..    1402    1485 .. 0.51

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 1.8
  PRKG1_interact  12 enerLkreLeelekelselkseleklkqqrqesvskrssllelekr 57 
                     e+++++r+L ++e +     s+++ +++q+     + + l+ +  +
      EEA19727.1  90 EEKEMQRKLMDIESSFLPEPSTIDMAATQN--AGVDDTYLVGVPTQ 133
                     667778888888888888888777777553..33333333333333 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.05
  PRKG1_interact  56 krerrslerkisel.eeelkeleeLraenqrLkdEngALiRViskLs 101
                     +  +++l+++  e   e + e  eL++++ +L++En+ + R i  L 
      EEA19727.1 476 HFLNEALNKRSEEGiKEMISENVELKSDKIKLQKENQGMKRTIRNLE 522
                     333444444444432455677899***************99998775 PP

  == domain 3  score: -0.6 bits;  conditional E-value: 0.73
  PRKG1_interact   9 ekeenerLkreLeelekelselkseleklkqqrqesvskrssllelekrerrslerkiseleeelkeleeLrae 82 
                      ++en+ +kr++++lek+l++++s+ + +++  + ++s+  +  ++e++e   l ++i  +e    e+e+Lr+e
      EEA19727.1 507 LQKENQGMKRTIRNLEKQLKDSQSNKSGVDT--EGETSEDDKRNDVEEEELIFLRERIETYEV---EIERLRTE 575
                     2333333333333333333333333333221..123344444444444444444444443333...33444433 PP

  == domain 4  score: 0.3 bits;  conditional E-value: 0.37
  PRKG1_interact  16 LkreLeelekelselkseleklkqqrqe.......svskrssllelekrerrslerkisel.....eeelkeleeLraenqrLkdEn 90 
                     L++++e+ e e+++l++e    ++++++         ++r + +e+  re+r++ + + +      e+   e ++Lr e  r+k+E 
      EEA19727.1 558 LRERIETYEVEIERLRTESIVRESEKRRlaeivksMGENRPADSEAGAREEREMWKDMLDAetaarEQAEDENRKLRDEILRMKAEG 644
                     777777777777777765333222222245555544455666667777777777777766544444666688889999999999995 PP

  == domain 5  score: 4.7 bits;  conditional E-value: 0.016
  PRKG1_interact   7 eeekeenerLkreLeelekelselkseleklkqqrqesvskrssllelekrerrslerkis...eleeelkeleeLraenqrLkdE 89 
                     e++++en++L++e+ +++ e   + se  +       +  ++ s ++ + +++r  +r+++    + + l e+e L++en+ L+ E
      EEA19727.1 624 EQAEDENRKLRDEILRMKAEGIATGSEAGRFG-----RAGRKGSFISHSTTSERDHDRRLTvpsSTGSTLVEIELLKKENAELRRE 704
                     57889999999999999999999999888876.....346677777778888888888887665789999*************988 PP

  == domain 6  score: 4.8 bits;  conditional E-value: 0.015
  PRKG1_interact   6 YeeekeenerLkreLeelekelselkseleklkqqrqe............svskrssllelekrerrslerkiseleeelkele..eLraenqrL 86 
                      ++ ++e+erL +e+e+l+ + +              e            ++++r++  + ++ ++ + e ++s++e e  e++  eLr + + L
      EEA19727.1 712 LTSRNREKERLYQEIEDLKLQRR--------------EggrsiagdsifeRSASRAHARSSSRASNGTRESRLSDTERESLEVRngELRDQVSTL 792
                     33344455555555555555555..............45555555554448888888899999999999*******99987665237******** PP

  PRKG1_interact  87 kdEngAL 93 
                     k En+ L
      EEA19727.1 793 KLENQGL 799
                     ***9876 PP

  == domain 7  score: -11.2 bits;  conditional E-value: 5
  PRKG1_interact  10 keenerLkreLeelekelselkseleklkqqrqe....svskrssllelekrerrslerkiseleeelkeleeLraenq 84 
                     k en+ L+++L+e + el+ l +  +    q +e                   +++ ++ ++  ee    l++L+ae q
      EEA19727.1 793 KLENQGLRSQLDEYTAELEALDKAYQADVDQAEEelqiL--------------QQERDQALQVAEEREAALQDLKAEAQ 857
                     334444444444444444444333333222211112221..............12222222223444445555554444 PP

  == domain 8  score: -4.1 bits;  conditional E-value: 5
  PRKG1_interact  17 kreLeelekelselkseleklkqqrqe...svskrssllelekrerrslerkiseleeelkele.eLraenqrLkd 88 
                     ++eLe++++e+++l+++l +++ + q+   ++++++  + + ++e+ + + +isel++elk  + +L+ e+++ k+
      EEA19727.1 920 QQELEDSNREIESLEKNLFEANGKVQRltvQIESSQGEITFLREEQDADKIRISELDSELKAYRiHLQVEKEKTKE 995
                     4556666666666655555555443333234555555566677777777778888888887654355555555443 PP

  == domain 9  score: -8.1 bits;  conditional E-value: 5
  PRKG1_interact   11 eenerLkreLeelekelselkseleklkqq....rqesvskrssllelek 56  
                      +e+++ +r +++l++e s +k e+ +lk++    + +  + +++l+ele+
      EEA19727.1 1013 KEKQEVQRIMNDLNREASAAKDEIRRLKKTlsarEIDAATWKERLMELEN 1062
                      45566666666666666666666666664432211113333334444444 PP

  == domain 10  score: -6.6 bits;  conditional E-value: 5
  PRKG1_interact    5 LYeeekeenerLkreLeelekelselkseleklkqqrqe...svskrssllelekrerrslerkiseleeelk 74  
                      L e+   e+++L + L++ ++  +  k +++++ +++q+    +s+++s ++  ++ r++  ++++ le++lk
      EEA19727.1 1116 LLESHGLESRKLGDLLDRERQARRADKHSFDQALKSQQQasrTISQHNSRISDLESARSQDRKRYASLEQQLK 1188
                      5555556666666666666666666666666554443322325555555555556666666667777777776 PP

  == domain 11  score: -3.9 bits;  conditional E-value: 5
  PRKG1_interact   17 kreLeelekelselkselekl 37  
                      +++++++e++l++  ++le+ 
      EEA19727.1 1258 RTRIRQVERDLTKEYQSLEHN 1278
                      566777777777777766664 PP

  == domain 12  score: 17.8 bits;  conditional E-value: 1.3e-06
  PRKG1_interact    8 eekeenerLkreLeelekelselkseleklkqqrqesvskrssllelekrerrslerkiseleeelkeleeLraenqrLkdEngA 92  
                          ++e L + +++++  l ++ s+ +k + +++  +  +ss++ +e +++ s +rk  + e+++  +++Lr+   rLk+E  A
      EEA19727.1 1318 TTAIDQEPLASPVSRTQSTLVRSDSRGKKGTLSHSPPSMPQSSTTLVETSSSTSSQRKPHDSEQDNVMIQRLRELERRLKNERTA 1402
                      5566788999999999999*99***9999999988889999999999***********************************887 PP

  == domain 13  score: 1.5 bits;  conditional E-value: 0.15
  PRKG1_interact    5 LYeeekeenerLkreLeelekelselkseleklkqqrqes 44  
                        e+  +ene+L++eLe+               + +r+++
      EEA19727.1 1413 RLEQRDAENEELRAELER--------------ERMRRSTR 1438
                      335555555555555554..............44333332 PP

>> DUF2935  Domain of unknown function (DUF2935)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.3    0.0021       7.6      58      93 ..     992    1047 ..     791    1101 .. 0.72
   2 ?   -0.1   0.2       0.3   1.1e+03      40      90 ..    1142    1188 ..    1123    1205 .. 0.63

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0021
     DUF2935   58 v....................rasseleeavakLneealkltreliqFkkellekv 93  
                                       + ++e ++ +++Ln+ea ++ +e++++kk l  + 
  EEA19727.1  992 KtkeletrlaeerhqrevvgsKEKQEVQRIMNDLNREASAAKDEIRRLKKTLSARE 1047
                  04444444445555555555444455555556666666666666666666655443 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.3
     DUF2935   40 kkeFekllaeavelseglv..........rasseleeavakLneealkltreliqFkkell 90  
                  k++F++ l++++++s ++           +                 +  +++ ++ ++l+
  EEA19727.1 1142 KHSFDQALKSQQQASRTISqhnsrisdleS--------------ARSQDRKRYASLEQQLK 1188
                  788999999999988777444444444443..............43333333333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1499 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2307  (0.128674); expected 358.6 (0.02)
Passed bias filter:                      487  (0.0271627); expected 358.6 (0.02)
Passed Vit filter:                       131  (0.0073066); expected 17.9 (0.001)
Passed Fwd filter:                        62  (0.00345808); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 2.28u 0.45s 00:00:02.73 Elapsed: 00:00:00.73
# Mc/sec: 6158.84
//
Query:       EEA19728.1  [L=287]
Description: RAS small monomeric GTPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.8e-39  133.5   0.0    2.6e-37  127.9   0.0    2.2  1  Ras       Ras family
    2.9e-11   43.6   0.0    1.2e-10   41.6   0.0    2.0  2  Roc       Ras of Complex, Roc, domain of DAPkinase
    2.5e-05   23.8   0.1      0.021   14.3   0.0    2.2  2  Arf       ADP-ribosylation factor family
     0.0037   17.3   0.0     0.0074   16.4   0.0    1.5  1  MMR_HSR1  50S ribosome-binding GTPase
  ------ inclusion threshold ------
      0.089   12.3   0.1        1.4    8.4   0.0    2.6  2  GTP_EFTU  Elongation factor Tu GTP binding domain


Domain annotation for each model (and alignments):
>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.9   0.0   7.3e-41   2.6e-37       3     161 ..       8     189 ..       6     190 .. 0.95

  Alignments for each domain:
  == domain 1  score: 127.9 bits;  conditional E-value: 7.3e-41
                 EEEESTTSSHHHHHHHHHHSSCSSSCTTTSSEEEEEEEEEETTEEEEEEEEEETTSGGGHHHHHHHHTTESEEEEEEETTBHHHHHTHHHHHHHHHHHS CS
         Ras   3 vlvGdsavGKtslllrfvkdkFkeeyesTigvdfytkeievdgkevkleiwDTAGqeefkslrelyyrdaegillvyditsresfenvkkwveeikrva 101
                  + Gd+++GK+s++lr v++++ +ey++Ti +d+y+ + ++dg+++ l+i DTAGqee++ l  ++  +++++l+vydit++ s+e ++ +++ i   a
  EEA19728.1   8 TICGDGGCGKSSITLRLVRSQWMHEYDPTI-EDSYSVTRNIDGTDYFLSITDTAGQEEYRGLWAASNLKSDAFLMVYDITHQPSLEALDYFMDMIDIEA 105
                 689***************************.*************************************************************9998888 PP

                 T........................TTSEEEEEEETTTGGGG-SS-HHHHHHHHHHHTSEEEEEBTTTTCTHHHHHHHHHHHHH CS
         Ras 102 e........................envpivLvGnKvDleekravsteegeelakelglkfletSAktnenveeafeellreil 161
                 e                           + ++ GnK+Dl++ ra+s+++g e+a+++g+ f+etSA++  n+ee+f  ++r++ 
  EEA19728.1 106 EqrlednqrimkelgsearnlqvgmPPPVKIIAGNKCDLKDARAISARDGLEYARKHGCGFMETSAREIVNIEETFALIVRRVV 189
                 888999************98887765567899************************************************9875 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.6   0.0   3.4e-14   1.2e-10       2     104 ..       7     103 ..       6     115 .. 0.84
   2 ?   -1.4   0.0      0.72   2.6e+03     108     119 ..     132     143 ..     100     144 .. 0.68

  Alignments for each domain:
  == domain 1  score: 41.6 bits;  conditional E-value: 3.4e-14
                 EEEESSTTSSHHHHHHCHCT-CCC-EEETTTTEEEEEEECGGSGGCTTBTTTTCEEEEEEEE-SGGCTTTT-HHHHCTSCEEEEEEEGHHH...HCHHH CS
         Roc   2 vvlvGdsgvGKtsllkrfvedkfsekekstigvdfltkevtkikgvendkkvkkvklniWDtaGqerfrslhplylreaalailvydsrss...enlke 97 
                 + ++Gd+g GK+s+  r+v+++  +++++ti  +++ ++  +i+g       +++ l+i DtaGqe++r l      +++++++vyd +++   e l++
  EEA19728.1   7 ITICGDGGCGKSSITLRLVRSQWMHEYDPTIEDSYSVTR--NIDG-------TDYFLSITDTAGQEEYRGLWAASNLKSDAFLMVYDITHQpslEALDY 96 
                 689*****************************9997764..5666.......4578*******************************664422367777 PP

                 HHHHHHH CS
         Roc  98 Wlkelkk 104
                  ++ ++ 
  EEA19728.1  97 FMDMIDI 103
                 7777665 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.72
                 SS-EEEEEE-TT CS
         Roc 108 kspvilvgnkiD 119
                   + i+ gnk+D
  EEA19728.1 132 PPVKIIAGNKCD 143
                 344589999999 PP

>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   5.8e-06     0.021      15      94 ..       5      88 ..       1      95 [. 0.82
   2 !    7.8   0.0   0.00056         2      87     133 ..      99     150 ..      89     188 .. 0.75

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 5.8e-06
                EEEEEEESTTSSHHHHHHHHHHSSCEE.CSSSSSEE...EEEEEETTEEEEEEEE-SSGGGGGGGGGGCTTESEEEEEEETT-C CS
         Arf 15 lrilllGLDnaGKtTilkklkleelvt.tvPTigfn...veeleiknlkftvwDvGGqeklRplWknYfektdavifvvDsadr 94
                + i + G  + GK+ i  +l   + ++   PTi      ++++   ++ +++ D  Gqe+ R lW     k da + v D +++
  EEA19728.1  5 VSITICGDGGCGKSSITLRLVRSQWMHeYDPTIEDSysvTRNIDGTDYFLSITDTAGQEEYRGLWAASNLKSDAFLMVYDITHQ 88
                66788888899*****99999888665389**9854211567888999**************************9999998876 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.00056
                 EEEETT-CTTHHHHHHHHHHHCTSGCCTTSEE.....EEEEE-TTSTTSS-H CS
         Arf  87 fvvDsadreRleeakeeLkalleeeelkeval.....lvlaNKqDlpealse 133
                  ++D   ++Rle+ ++ +k+l +e ++ +v +     ++ +NK Dl++a   
  EEA19728.1  99 DMIDIEAEQRLEDNQRIMKELGSEARNLQVGMpppvkIIAGNKCDLKDARAI 150
                 57999999**************999988774434444999******998643 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0   2.1e-06    0.0074       2      97 ..       7      98 ..       6     127 .. 0.68

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 2.1e-06
                EEEEESTTSSHHHHHHHHHTS......TEEESSSTTSSSSEEEEEEEETTEEEEEEECGGCSSHHHHHHHHHHHHHHHHCTSEEEEEEETT..TTCSHHHH CS
    MMR_HSR1  2 vaivGrpNvGKStLinaltge......kaivsdkpgtTrdinegrvklkgkeielvDtpGliegaseekglgkaflaleeadlillvvdas..eeklkpld 94
                + i G    GKS++  +l+++         ++d   +Tr+i    +      + ++Dt+G  e   e +gl  a  ++ ++d++l+v d++    +l++ld
  EEA19728.1  7 ITICGDGGCGKSSITLRLVRSqwmheyDPTIEDSYSVTRNIDGTDYF-----LSITDTAG-QE---EYRGLWAA--SNLKSDAFLMVYDIThqP-SLEALD 95
                7899999************9544433456888888899988888664.....89******.44...23344333..356789******998530.333333 PP

                HHH CS
    MMR_HSR1 95 eel 97
                  +
  EEA19728.1 96 YFM 98
                222 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0     0.097   3.5e+02       4      25 ..       5      26 ..       3      33 .. 0.86
   2 ?    8.4   0.0    0.0004       1.4      65     106 ..      46      88 ..      31     226 .. 0.80

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.097
                EEEEEEESTTSSHHHHHHHHHH CS
    GTP_EFTU  4 rnigiighvDhGKtTLtdrLly 25
                + i+i+g+   GK+++t rL+ 
  EEA19728.1  5 VSITICGDGGCGKSSITLRLVR 26
                5799*************99986 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0004
                 T.TCSSEEEEEEEESSSGGGHHHHHHHHHT-SEEEEEEETTTB CS
    GTP_EFTU  65 k.etkkylinliDtPGHvdFskevirglrvlDgavlvvdaveG 106
                 + ++++y +++ Dt G +++     ++  + D  ++v d+++ 
  EEA19728.1  46 NiDGTDYFLSITDTAGQEEYRGLWAASNLKSDAFLMVYDITHQ 88 
                 336899*********************************9965 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (287 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       693  (0.0386525); expected 358.6 (0.02)
Passed bias filter:                      486  (0.0271069); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.49
# Mc/sec: 1745.96
//
Query:       EEA19729.1  [L=963]
Description: GATA transcription factor LreA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    4.6e-28   97.5   0.0    3.2e-16   59.5   0.0    3.5  3  PAS_9      PAS domain
    4.3e-23   81.4   0.0    2.3e-13   50.2   0.0    3.9  4  PAS_3      PAS fold
    3.2e-16   59.3   0.0    3.3e-07   30.3   0.0    3.6  3  PAS        PAS fold
    9.9e-15   53.9   9.6    1.7e-14   53.1   8.9    1.9  2  GATA       GATA zinc finger
    3.9e-09   36.6   0.0    3.2e-05   24.0   0.0    3.0  3  PAS_11     PAS domain
    1.4e-08   35.0   0.0     0.0056   16.9   0.0    3.4  3  PAS_4      PAS fold
     0.0032   17.4   0.0      0.058   13.4   0.0    2.4  2  PAS_8      PAS domain
  ------ inclusion threshold ------
       0.57   10.1   3.6        1.2    9.1   3.6    1.6  1  Nudix_N_2  Nudix N-terminal


Domain annotation for each model (and alignments):
>> PAS_9  PAS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.5   0.0   1.4e-19   3.2e-16       3     103 ..     335     449 ..     333     450 .. 0.86
   2 !   21.6   0.0   8.6e-08   0.00019      11      80 ..     535     603 ..     525     622 .. 0.84
   3 !   12.1   0.0   7.6e-05      0.17      10      73 ..     653     715 ..     648     730 .. 0.82

  Alignments for each domain:
  == domain 1  score: 59.5 bits;  conditional E-value: 1.4e-19
       PAS_9   3 gilidnpdg...rilyaNeaalrllGyspeevlgksitdlf.............vtdpeanerlraaleqgrkkerevevvlirkngetfwvlltaspv 85 
                 +++++++ +   +i+y+++a++rl+Gy++ e+lg++++ l+             + d+++  rl++ +++    e +v ++++rk g+ f++llt++p+
  EEA19729.1 335 AFILCDMTChddPIVYVSDAFERLTGYTKHEILGRNCRFLQspdgkvdpgmkrkYVDDQTVWRLKEKIQARA--EVQVSMINYRKGGQSFMNLLTMIPI 431
                 5665444444549****************************9888888888777777777777777777777..************************* PP

       PAS_9  86 kdddgelvgiivilrDit 103
                 +++   +++++++++D+ 
  EEA19729.1 432 HWNTTDYRFYVGFQVDLV 449
                 ****************85 PP

  == domain 2  score: 21.6 bits;  conditional E-value: 8.6e-08
       PAS_9  11 grilyaNeaalrllGyspeevlgksitdlfvtdpeanerlraaleqgrk.kerevevvlirkngetfwvll 80 
                 g  ly +++  rll y+p e++g+si+ ++  +p++   + + l+q ++ ++ +v + ++rkn +++w++ 
  EEA19729.1 535 GLFLYLSQSSSRLLEYDPSELVGQSISSVC--HPSDIAPVTRELKQSTTgSPVSVIYRFRRKNSGYVWFES 603
                 5456999***********************..8888888888888888899*****************874 PP

  == domain 3  score: 12.1 bits;  conditional E-value: 7.6e-05
       PAS_9  10 dgrilyaNeaalrllGyspeevlgksitdlfvtdpeanerlraaleqgrk.kerevevvlirkng 73 
                 +g+ l+++  a+ ll  +p e++gk i d++   ++++ +l +ale  r+  + ++  ++++k g
  EEA19729.1 653 SGMFLFVSSNARVLLDRTPGEMVGKGIQDFM--RSDSRGELGKALEVARTgRQATFKHEIRHKRG 715
                 68899**************************..99999999999998887756666666665555 PP

>> PAS_3  PAS fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       5.4   1.2e+04      26      40 ..       9      23 ..       5      31 .. 0.84
   2 !   13.5   0.0     3e-05     0.068       1      22 [.     348     369 ..     348     378 .. 0.87
   3 !   50.2   0.0     1e-16   2.3e-13       2      80 ..     538     614 ..     537     621 .. 0.91
   4 !   13.0   0.0   4.2e-05     0.094       2      74 ..     657     726 ..     656     740 .. 0.87

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 5.4
       PAS_3 26 wldlvhpeDrervre 40
                +++ + p+D+e++r+
  EEA19729.1  9 YASQIPPQDQEQARR 23
                678899*****9997 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 3e-05
       PAS_3   1 iiyvserveeilGyspeellgk 22 
                 i+yvs+++e+++Gy+++e+lg+
  EEA19729.1 348 IVYVSDAFERLTGYTKHEILGR 369
                 58******************99 PP

  == domain 3  score: 50.2 bits;  conditional E-value: 1e-16
       PAS_3   2 iyvserveeilGyspeellgkveswldlvhpeDrervrealqealkkgepyegeyRirrkdGeyrwveararvi.rdeng 80 
                 +y+s++ +++l y+p+el g+  s+ +++hp D++ v ++l+++  +g+p+++ yR+rrk+ +y+w+e++++ +    +g
  EEA19729.1 538 LYLSQSSSRLLEYDPSELVGQ--SISSVCHPSDIAPVTRELKQST-TGSPVSVIYRFRRKNSGYVWFESYGSLHiEPGKG 614
                 799******************..*********************7.************************9988555555 PP

  == domain 4  score: 13.0 bits;  conditional E-value: 4.2e-05
       PAS_3   2 iyvserveeilGyspeellgkveswldlvhpeDrervrealqealkkgepyegeyRirrkdGeyrwveararv 74 
                 ++vs + + +l+ +p e+ gk   + d++  + r ++ +al+ ++++g++ ++ + ir+k G++   ++  ++
  EEA19729.1 657 LFVSSNARVLLDRTPGEMVGK--GIQDFMRSDSRGELGKALE-VARTGRQATFKHEIRHKRGHVLQAQTILFP 726
                 7999999**************..******************8.66788889***********99777766555 PP

>> PAS  PAS fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   6.1e-06     0.014      21      50 ..     346     375 ..     334     445 .. 0.79
   2 !   30.3   0.0   1.5e-10   3.3e-07       4     111 ..     518     623 ..     515     625 .. 0.89
   3 !    9.3   0.0   0.00048       1.1      19      81 ..     652     714 ..     650     759 .. 0.85

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 6.1e-06
                 SBEEEECHHHHHHHSSTHHHCTTSBGGGGB CS
         PAS  21 grilyvNaaaeellGlsreevlgkslldli 50 
                   i+yv++a+e+l+G++  e+lg++   l 
  EEA19729.1 346 DPIVYVSDAFERLTGYTKHEILGRNCRFLQ 375
                 569*********************976544 PP

  == domain 2  score: 30.3 bits;  conditional E-value: 1.5e-10
                 HHHHHHSSSEEEEEETTSBEEEECHHHHHHHSSTHHHCTTSBGGGGBSTTHHHHHHHHHHHHHHHTT-ECCCCEEEEC..TTSSEEEEEEEEEEEEETT CS
         PAS   4 raileslpdpifvvDedgrilyvNaaaeellGlsreevlgkslldliheeddaelaelleqlleqgeesrageisfkl..rdgrpihlevraspvrdag 100
                 r ile+++d i v+  +g +ly +++  +ll ++++e++g+s++ + h+     + + +++ l+q++ ++ + +  ++  ++ +++++e   s  +++g
  EEA19729.1 518 RVILENADDVIHVLSLRGLFLYLSQSSSRLLEYDPSELVGQSISSVCHPS----DIAPVTRELKQSTTGSPVSVIYRFrrKNSGYVWFESYGSLHIEPG 612
                 789*****************************************999999....677778777777777777777777779***********9999999 PP

                 EEEEEEEEEEE CS
         PAS 101 geilgflgvlr 111
                 + ++++++v+r
  EEA19729.1 613 KGRKCLILVGR 623
                 98889998887 PP

  == domain 3  score: 9.3 bits;  conditional E-value: 0.00048
                 TTSBEEEECHHHHHHHSSTHHHCTTSBGGGGBSTTHHHHHHHHHHHHHHHTT-ECCCCEEEEC CS
         PAS  19 edgrilyvNaaaeellGlsreevlgkslldliheeddaelaelleqlleqgeesrageisfkl 81 
                  +g +l+v+++a+ ll  ++ e++gk + d++  +++ el ++le ++  ++     ei+ k+
  EEA19729.1 652 ISGMFLFVSSNARVLLDRTPGEMVGKGIQDFMRSDSRGELGKALEVARTGRQATFKHEIRHKR 714
                 57999****************************998778888888888888888888887666 PP

>> GATA  GATA zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0       3.7   8.3e+03       8      19 ..     800     811 ..     800     812 .. 0.84
   2 !   53.1   8.9   7.6e-18   1.7e-14       1      34 [.     892     925 ..     892     927 .. 0.96

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 3.7
        GATA   8 kTplWRrgpdgn 19 
                 +T+  R gp+++
  EEA19729.1 800 NTSSVRAGPEQK 811
                 69999****975 PP

  == domain 2  score: 53.1 bits;  conditional E-value: 7.6e-18
        GATA   1 CsnCgttkTplWRrgpdgnksLCnaCGlyykkkg 34 
                 C+nCgt++Tp+WRrgp+g++ LCn+CGl+++k++
  EEA19729.1 892 CANCGTRNTPEWRRGPSGHRDLCNSCGLRWAKQN 925
                 *******************************986 PP

>> PAS_11  PAS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.1       3.9   8.8e+03      78     103 ..     387     413 ..     385     414 .. 0.81
   2 !   24.0   0.0   1.4e-08   3.2e-05       9      89 ..     532     607 ..     526     620 .. 0.86
   3 !    9.1   0.0   0.00061       1.4       2      91 ..     644     728 ..     643     748 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 3.9
      PAS_11  78 dkfvkvktksklfkn.qksneqdfima 103
                  k+v  +t+++l+++ q   e+++ m+
  EEA19729.1 387 RKYVDDQTVWRLKEKiQARAEVQVSMI 413
                 589999999999998888888888775 PP

  == domain 2  score: 24.0 bits;  conditional E-value: 1.4e-08
      PAS_11   9 didgkIisvDtsaLrasfslglekeelvgrsiydLchpqdlstlkshlrevissngeatsslyRLrlsqdkfvkvktkskl 89 
                 ++ g ++ + +   ++s  l +  +elvg si   chp d   +++ l++ +  +g   s +yR+r ++  +v+    + l
  EEA19729.1 532 SLRGLFLYLSQ---SSSRLLEYDPSELVGQSISSVCHPSDIAPVTRELKQST--TGSPVSVIYRFRRKNSGYVWFESYGSL 607
                 56666777777...88888999****************************88..9*******************8776665 PP

  == domain 3  score: 9.1 bits;  conditional E-value: 0.00061
      PAS_11   2 eqfttrldidgkIisvDtsaLrasfslglekeelvgrsiydLchpqdlstlkshlrevissngeatsslyRLrlsqdkfvkvktksklfk 91 
                 + ++t+++i+g ++ v +   +a + l  +  e+vg+ i+d++  + + +l ++l+     +g++++    +r +++++++++t +   +
  EEA19729.1 644 NDLWTKISISGMFLFVSS---NARVLLDRTPGEMVGKGIQDFMRSDSRGELGKALEVAR--TGRQATFKHEIRHKRGHVLQAQTILFPGD 728
                 5689**************...*********************************97666..77777888889999999999999776655 PP

>> PAS_4  PAS fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.0     0.034        75      17      41 ..     348     372 ..     334     408 .. 0.85
   2 !   16.9   0.0   2.5e-06    0.0056       1      87 [.     521     606 ..     521     624 .. 0.82
   3 !   10.3   0.0   0.00029      0.66      12      83 ..     651     720 ..     644     740 .. 0.76

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.034
       PAS_4  17 vlyaNaaaaelfgappeellGktla 41 
                 ++y++ a+++l g++ +e+lG+ ++
  EEA19729.1 348 IVYVSDAFERLTGYTKHEILGRNCR 372
                 89********************998 PP

  == domain 2  score: 16.9 bits;  conditional E-value: 2.5e-06
       PAS_4   1 ldslpdalavldpdgrvlyaNaaaaelfgappeellGktlaellpeedaarleralrrvlegeepiefleelllpgeerhyelrllP 87 
                 l++  d+++vl+  g +ly+++++ +l+ ++p el+G++  ++  ++d a++ r l++  +g  p++     ++  ++ ++  ++  
  EEA19729.1 521 LENADDVIHVLSLRGLFLYLSQSSSRLLEYDPSELVGQSISSVCHPSDIAPVTRELKQSTTG-SPVSVIYRFRRKNSGYVWFESYGS 606
                 78999***************************************************998887.577777777775555555555555 PP

  == domain 3  score: 10.3 bits;  conditional E-value: 0.00029
       PAS_4  12 dpdgrvlyaNaaaaelfgappeellGktlaellpeedaarleralrrvlegeepiefleelllpgeerhyel 83 
                 +  g +l+++ +a+ l+ ++p e++Gk  ++++  +++++l  al+ + +g + ++f +e ++ +++++++ 
  EEA19729.1 651 SISGMFLFVSSNARVLLDRTPGEMVGKGIQDFMRSDSRGELGKALEVARTG-RQATFKHEIRH-KRGHVLQA 720
                 566778899999999**************************9999755555.55555555555.45555554 PP

>> PAS_8  PAS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.0   2.6e-05     0.058      14      46 ..     336     372 ..     331     391 .. 0.77
   2 ?    1.0   0.0       0.2   4.6e+02       5      46 ..     519     561 ..     516     582 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 2.6e-05
       PAS_8  14 iavvd....lgdrivdvNqaalellGys.adlkgellg 46 
                  +++d    ++  iv+v +a+++l+Gy+  +++g  ++
  EEA19729.1 336 FILCDmtchDDP-IVYVSDAFERLTGYTkHEILGRNCR 372
                 566555555779.***************9999998774 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.2
       PAS_8   5 alfesspdgiavvd.lgdrivdvNqaalellGys.adlkgellg 46 
                  ++e+++d i v+  +g ++++  q+  +ll y+  +l g+ + 
  EEA19729.1 519 VILENADDVIHVLSlRG-LFLYLSQSSSRLLEYDpSELVGQSIS 561
                 58899999999887444.5***************9999998884 PP

>> Nudix_N_2  Nudix N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   3.6   0.00053       1.2       3      29 ..     892     918 ..     890     919 .. 0.96

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00053
                 -TTT--B-EEE--TT-SS-EEEETTTT CS
   Nudix_N_2   3 CsqCGtpvelripdgDnreRlvCpaCg 29 
                 C +CGt+ + +   g + +R  C++Cg
  EEA19729.1 892 CANCGTRNTPEWRRGPSGHRDLCNSCG 918
                 **************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (963 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       606  (0.0338); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.72u 0.31s 00:00:01.03 Elapsed: 00:00:00.46
# Mc/sec: 6296.94
//
Query:       EEA19730.1  [L=937]
Description: GATA transcription factor LreA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    4.1e-28   97.7   0.0      3e-16   59.5   0.0    3.5  3  PAS_9      PAS domain
    4.1e-23   81.5   0.0    2.2e-13   50.3   0.0    3.8  4  PAS_3      PAS fold
    2.9e-16   59.5   0.0    3.1e-07   30.4   0.0    3.6  3  PAS        PAS fold
    4.2e-15   55.1   7.4    7.5e-15   54.2   6.7    1.8  2  GATA       GATA zinc finger
    3.6e-09   36.8   0.0    3.1e-05   24.1   0.0    3.0  3  PAS_11     PAS domain
    1.3e-08   35.1   0.0     0.0054   17.0   0.0    3.4  3  PAS_4      PAS fold
      0.003   17.5   0.0      0.056   13.5   0.0    2.4  2  PAS_8      PAS domain
  ------ inclusion threshold ------
       0.17   12.6   0.0        9.7    6.9   0.0    2.8  2  PAS_2      PAS fold
       0.55   10.2   3.6        1.1    9.2   3.6    1.6  1  Nudix_N_2  Nudix N-terminal


Domain annotation for each model (and alignments):
>> PAS_9  PAS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.5   0.0   1.5e-19     3e-16       3     103 ..     335     449 ..     333     450 .. 0.86
   2 !   21.7   0.0   9.3e-08   0.00019      11      80 ..     535     603 ..     525     622 .. 0.84
   3 !   12.2   0.0   8.3e-05      0.16      10      73 ..     653     715 ..     648     730 .. 0.82

  Alignments for each domain:
  == domain 1  score: 59.5 bits;  conditional E-value: 1.5e-19
       PAS_9   3 gilidnpdg...rilyaNeaalrllGyspeevlgksitdlf.............vtdpeanerlraaleqgrkkerevevvlirkngetfwvlltaspv 85 
                 +++++++ +   +i+y+++a++rl+Gy++ e+lg++++ l+             + d+++  rl++ +++    e +v ++++rk g+ f++llt++p+
  EEA19730.1 335 AFILCDMTChddPIVYVSDAFERLTGYTKHEILGRNCRFLQspdgkvdpgmkrkYVDDQTVWRLKEKIQARA--EVQVSMINYRKGGQSFMNLLTMIPI 431
                 5665444444549****************************9888888888777777777777777777777..************************* PP

       PAS_9  86 kdddgelvgiivilrDit 103
                 +++   +++++++++D+ 
  EEA19730.1 432 HWNTTDYRFYVGFQVDLV 449
                 ****************85 PP

  == domain 2  score: 21.7 bits;  conditional E-value: 9.3e-08
       PAS_9  11 grilyaNeaalrllGyspeevlgksitdlfvtdpeanerlraaleqgrk.kerevevvlirkngetfwvll 80 
                 g  ly +++  rll y+p e++g+si+ ++  +p++   + + l+q ++ ++ +v + ++rkn +++w++ 
  EEA19730.1 535 GLFLYLSQSSSRLLEYDPSELVGQSISSVC--HPSDIAPVTRELKQSTTgSPVSVIYRFRRKNSGYVWFES 603
                 5456999***********************..8888888888888888899*****************874 PP

  == domain 3  score: 12.2 bits;  conditional E-value: 8.3e-05
       PAS_9  10 dgrilyaNeaalrllGyspeevlgksitdlfvtdpeanerlraaleqgrk.kerevevvlirkng 73 
                 +g+ l+++  a+ ll  +p e++gk i d++   ++++ +l +ale  r+  + ++  ++++k g
  EEA19730.1 653 SGMFLFVSSNARVLLDRTPGEMVGKGIQDFM--RSDSRGELGKALEVARTgRQATFKHEIRHKRG 715
                 68899**************************..99999999999998887756666666665555 PP

>> PAS_3  PAS fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       5.9   1.2e+04      26      40 ..       9      23 ..       5      31 .. 0.84
   2 !   13.5   0.0   3.3e-05     0.066       1      22 [.     348     369 ..     348     378 .. 0.87
   3 !   50.3   0.0   1.1e-16   2.2e-13       2      80 ..     538     614 ..     537     621 .. 0.91
   4 !   13.1   0.0   4.6e-05     0.091       2      74 ..     657     726 ..     656     740 .. 0.87

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 5.9
       PAS_3 26 wldlvhpeDrervre 40
                +++ + p+D+e++r+
  EEA19730.1  9 YASQIPPQDQEQARR 23
                678899*****9997 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 3.3e-05
       PAS_3   1 iiyvserveeilGyspeellgk 22 
                 i+yvs+++e+++Gy+++e+lg+
  EEA19730.1 348 IVYVSDAFERLTGYTKHEILGR 369
                 58******************99 PP

  == domain 3  score: 50.3 bits;  conditional E-value: 1.1e-16
       PAS_3   2 iyvserveeilGyspeellgkveswldlvhpeDrervrealqealkkgepyegeyRirrkdGeyrwveararvi.rdeng 80 
                 +y+s++ +++l y+p+el g+  s+ +++hp D++ v ++l+++  +g+p+++ yR+rrk+ +y+w+e++++ +    +g
  EEA19730.1 538 LYLSQSSSRLLEYDPSELVGQ--SISSVCHPSDIAPVTRELKQST-TGSPVSVIYRFRRKNSGYVWFESYGSLHiEPGKG 614
                 799******************..*********************7.************************9988555555 PP

  == domain 4  score: 13.1 bits;  conditional E-value: 4.6e-05
       PAS_3   2 iyvserveeilGyspeellgkveswldlvhpeDrervrealqealkkgepyegeyRirrkdGeyrwveararv 74 
                 ++vs + + +l+ +p e+ gk   + d++  + r ++ +al+ ++++g++ ++ + ir+k G++   ++  ++
  EEA19730.1 657 LFVSSNARVLLDRTPGEMVGK--GIQDFMRSDSRGELGKALE-VARTGRQATFKHEIRHKRGHVLQAQTILFP 726
                 7999999**************..******************8.66788889***********99777766555 PP

>> PAS  PAS fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   6.7e-06     0.013      21      50 ..     346     375 ..     334     445 .. 0.79
   2 !   30.4   0.0   1.6e-10   3.1e-07       4     111 ..     518     623 ..     515     625 .. 0.89
   3 !    9.4   0.0   0.00052         1      19      81 ..     652     714 ..     650     759 .. 0.85

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 6.7e-06
                 SBEEEECHHHHHHHSSTHHHCTTSBGGGGB CS
         PAS  21 grilyvNaaaeellGlsreevlgkslldli 50 
                   i+yv++a+e+l+G++  e+lg++   l 
  EEA19730.1 346 DPIVYVSDAFERLTGYTKHEILGRNCRFLQ 375
                 569*********************976544 PP

  == domain 2  score: 30.4 bits;  conditional E-value: 1.6e-10
                 HHHHHHSSSEEEEEETTSBEEEECHHHHHHHSSTHHHCTTSBGGGGBSTTHHHHHHHHHHHHHHHTT-ECCCCEEEEC..TTSSEEEEEEEEEEEEETT CS
         PAS   4 raileslpdpifvvDedgrilyvNaaaeellGlsreevlgkslldliheeddaelaelleqlleqgeesrageisfkl..rdgrpihlevraspvrdag 100
                 r ile+++d i v+  +g +ly +++  +ll ++++e++g+s++ + h+     + + +++ l+q++ ++ + +  ++  ++ +++++e   s  +++g
  EEA19730.1 518 RVILENADDVIHVLSLRGLFLYLSQSSSRLLEYDPSELVGQSISSVCHPS----DIAPVTRELKQSTTGSPVSVIYRFrrKNSGYVWFESYGSLHIEPG 612
                 789*****************************************999999....677778777777777777777777779***********9999999 PP

                 EEEEEEEEEEE CS
         PAS 101 geilgflgvlr 111
                 + ++++++v+r
  EEA19730.1 613 KGRKCLILVGR 623
                 98889998887 PP

  == domain 3  score: 9.4 bits;  conditional E-value: 0.00052
                 TTSBEEEECHHHHHHHSSTHHHCTTSBGGGGBSTTHHHHHHHHHHHHHHHTT-ECCCCEEEEC CS
         PAS  19 edgrilyvNaaaeellGlsreevlgkslldliheeddaelaelleqlleqgeesrageisfkl 81 
                  +g +l+v+++a+ ll  ++ e++gk + d++  +++ el ++le ++  ++     ei+ k+
  EEA19730.1 652 ISGMFLFVSSNARVLLDRTPGEMVGKGIQDFMRSDSRGELGKALEVARTGRQATFKHEIRHKR 714
                 57999****************************998778888888888888888888887666 PP

>> GATA  GATA zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0       4.1   8.1e+03       8      19 ..     800     811 ..     800     812 .. 0.84
   2 !   54.2   6.7   3.8e-18   7.5e-15       1      33 [.     892     924 ..     892     926 .. 0.97

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 4.1
        GATA   8 kTplWRrgpdgn 19 
                 +T+  R gp+++
  EEA19730.1 800 NTSSVRAGPEQK 811
                 69999****975 PP

  == domain 2  score: 54.2 bits;  conditional E-value: 3.8e-18
        GATA   1 CsnCgttkTplWRrgpdgnksLCnaCGlyykkk 33 
                 C+nCgt++Tp+WRrgp+g++ LCn+CGl+++k+
  EEA19730.1 892 CANCGTRNTPEWRRGPSGHRDLCNSCGLRWAKQ 924
                 ******************************995 PP

>> PAS_11  PAS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.1       4.3   8.5e+03      78     103 ..     387     413 ..     385     414 .. 0.81
   2 !   24.1   0.0   1.5e-08   3.1e-05       9      89 ..     532     607 ..     526     620 .. 0.86
   3 !    9.1   0.0   0.00067       1.3       2      91 ..     644     728 ..     643     748 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 4.3
      PAS_11  78 dkfvkvktksklfkn.qksneqdfima 103
                  k+v  +t+++l+++ q   e+++ m+
  EEA19730.1 387 RKYVDDQTVWRLKEKiQARAEVQVSMI 413
                 589999999999998888888888775 PP

  == domain 2  score: 24.1 bits;  conditional E-value: 1.5e-08
      PAS_11   9 didgkIisvDtsaLrasfslglekeelvgrsiydLchpqdlstlkshlrevissngeatsslyRLrlsqdkfvkvktkskl 89 
                 ++ g ++ + +   ++s  l +  +elvg si   chp d   +++ l++ +  +g   s +yR+r ++  +v+    + l
  EEA19730.1 532 SLRGLFLYLSQ---SSSRLLEYDPSELVGQSISSVCHPSDIAPVTRELKQST--TGSPVSVIYRFRRKNSGYVWFESYGSL 607
                 56666777777...88888999****************************88..9*******************8776665 PP

  == domain 3  score: 9.1 bits;  conditional E-value: 0.00067
      PAS_11   2 eqfttrldidgkIisvDtsaLrasfslglekeelvgrsiydLchpqdlstlkshlrevissngeatsslyRLrlsqdkfvkvktksklfk 91 
                 + ++t+++i+g ++ v +   +a + l  +  e+vg+ i+d++  + + +l ++l+     +g++++    +r +++++++++t +   +
  EEA19730.1 644 NDLWTKISISGMFLFVSS---NARVLLDRTPGEMVGKGIQDFMRSDSRGELGKALEVAR--TGRQATFKHEIRHKRGHVLQAQTILFPGD 728
                 5689**************...*********************************97666..77777888889999999999999776655 PP

>> PAS_4  PAS fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.0     0.037        73      17      41 ..     348     372 ..     334     408 .. 0.85
   2 !   17.0   0.0   2.7e-06    0.0054       1      87 [.     521     606 ..     521     624 .. 0.82
   3 !   10.3   0.0   0.00032      0.64      12      83 ..     651     720 ..     644     740 .. 0.76

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.037
       PAS_4  17 vlyaNaaaaelfgappeellGktla 41 
                 ++y++ a+++l g++ +e+lG+ ++
  EEA19730.1 348 IVYVSDAFERLTGYTKHEILGRNCR 372
                 89********************998 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 2.7e-06
       PAS_4   1 ldslpdalavldpdgrvlyaNaaaaelfgappeellGktlaellpeedaarleralrrvlegeepiefleelllpgeerhyelrllP 87 
                 l++  d+++vl+  g +ly+++++ +l+ ++p el+G++  ++  ++d a++ r l++  +g  p++     ++  ++ ++  ++  
  EEA19730.1 521 LENADDVIHVLSLRGLFLYLSQSSSRLLEYDPSELVGQSISSVCHPSDIAPVTRELKQSTTG-SPVSVIYRFRRKNSGYVWFESYGS 606
                 78999***************************************************998887.577777777775555555555555 PP

  == domain 3  score: 10.3 bits;  conditional E-value: 0.00032
       PAS_4  12 dpdgrvlyaNaaaaelfgappeellGktlaellpeedaarleralrrvlegeepiefleelllpgeerhyel 83 
                 +  g +l+++ +a+ l+ ++p e++Gk  ++++  +++++l  al+ + +g + ++f +e ++ +++++++ 
  EEA19730.1 651 SISGMFLFVSSNARVLLDRTPGEMVGKGIQDFMRSDSRGELGKALEVARTG-RQATFKHEIRH-KRGHVLQA 720
                 566778899999999**************************9999755555.55555555555.45555554 PP

>> PAS_8  PAS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.0   2.8e-05     0.056      14      46 ..     336     372 ..     331     391 .. 0.77
   2 ?    1.0   0.0      0.22   4.4e+02       5      46 ..     519     561 ..     516     582 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.8e-05
       PAS_8  14 iavvd....lgdrivdvNqaalellGys.adlkgellg 46 
                  +++d    ++  iv+v +a+++l+Gy+  +++g  ++
  EEA19730.1 336 FILCDmtchDDP-IVYVSDAFERLTGYTkHEILGRNCR 372
                 566555555779.***************9999998774 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.22
       PAS_8   5 alfesspdgiavvd.lgdrivdvNqaalellGys.adlkgellg 46 
                  ++e+++d i v+  +g ++++  q+  +ll y+  +l g+ + 
  EEA19730.1 519 VILENADDVIHVLSlRG-LFLYLSQSSSRLLEYDpSELVGQSIS 561
                 58899999999887444.5***************9999998884 PP

>> PAS_2  PAS fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.15     3e+02      31      72 ..     540     581 ..     530     605 .. 0.83
   2 ?    6.9   0.0    0.0049       9.7      29      78 ..     657     706 ..     652     724 .. 0.81

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.15
                 EETTHHHHCSS-CCCCTTTCCCCCSECTTHHHHCCHS-CCCH CS
       PAS_2  31 vSeNaaemLglteekllgtdlralltassaalLekalsarei 72 
                 +S+  + +L+  + +l+g+ ++++ ++s +a + + l++ + 
  EEA19730.1 540 LSQSSSRLLEYDPSELVGQSISSVCHPSDIAPVTRELKQSTT 581
                 68888999*********************9999988887665 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0049
                 EEEETTHHHHCSS-CCCCTTTCCCCCSECTTHHHHCCHS-CCCHCCCCCE CS
       PAS_2  29 lqvSeNaaemLglteekllgtdlralltassaalLekalsareisllnpi 78 
                 l vS Na+ +L+ t+ + +g+ +++ +++ s   L kal+ ++      +
  EEA19730.1 657 LFVSSNARVLLDRTPGEMVGKGIQDFMRSDSRGELGKALEVARTGRQATF 706
                 569**********************************9998776654444 PP

>> Nudix_N_2  Nudix N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   3.6   0.00057       1.1       3      29 ..     892     918 ..     890     919 .. 0.96

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00057
                 -TTT--B-EEE--TT-SS-EEEETTTT CS
   Nudix_N_2   3 CsqCGtpvelripdgDnreRlvCpaCg 29 
                 C +CGt+ + +   g + +R  C++Cg
  EEA19730.1 892 CANCGTRNTPEWRRGPSGHRDLCNSCG 918
                 **************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (937 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       580  (0.0323498); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.68u 0.29s 00:00:00.97 Elapsed: 00:00:00.44
# Mc/sec: 6362.84
//
Query:       EEA19731.1  [L=1775]
Description: phospholipase D1 (PLD1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.1e-15   55.2   0.2    2.6e-07   30.5   0.1    2.7  2  PLDc      Phospholipase D Active site motif
    5.6e-13   48.9   0.0    1.8e-06   27.9   0.0    3.2  2  PLDc_2    PLD-like domain
      1e-08   35.1   0.2    4.8e-08   33.0   0.0    2.3  2  PX        PX domain


Domain annotation for each model (and alignments):
>> PLDc  Phospholipase D Active site motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.5   0.1   4.4e-11   2.6e-07       2      28 .]     907     933 ..     906     933 .. 0.96
   2 !   22.2   0.0   1.9e-08   0.00012       6      28 .]    1217    1239 ..    1212    1239 .. 0.92

  Alignments for each domain:
  == domain 1  score: 30.5 bits;  conditional E-value: 4.4e-11
                 TBEE---EEEETTTEEEEE---SSHHH CS
        PLDc   2 mgthHqKivivDdrvafvGgaNLcdgr 28 
                 ++ hH+K  i+D+++afvGg +Lc gr
  EEA19731.1 907 FWAHHEKLCIIDHTLAFVGGIDLCFGR 933
                 79**********************997 PP

  == domain 2  score: 22.2 bits;  conditional E-value: 1.9e-08
                  ---EEEETTTEEEEE---SSHHH CS
        PLDc    6 HqKivivDdrvafvGgaNLcdgr 28  
                  H+K ++vDdr a++G+aN++ ++
  EEA19731.1 1217 HAKCMVVDDRAAIIGSANINERS 1239
                  ********************996 PP

>> PLDc_2  PLD-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0   6.7e-07     0.004       4     100 ..     815     928 ..     812     942 .. 0.70
   2 !   27.9   0.0     3e-10   1.8e-06       3     119 ..    1086    1255 ..    1084    1259 .. 0.56

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 6.7e-07
      PLDc_2   4 liksAkksidiatyyf...........vsdreildallk.aakrgvkvrilldskkddagavdeaslkelkellleagvevrvfet.......llgslH 83 
                 +i++Ak+ i+i    +           +s+++ ld+ll+ +a++gvkv +++ ++++ ++++ + +  +++ l l+ ++ v+ +         +    H
  EEA19731.1 815 AINQAKDVIYIHDWWLspelymrrpaaISQKWRLDRLLQrKAQEGVKVFVIMYRNIN-SAVPIDSEYTKFSLLDLHPNIFVQRSPNqfrqntfF-WAHH 911
                 6777777777777766666666666666777779999888*************9776.444444555555555555555555543234434432.577* PP

      PLDc_2  84 aKlylidgktvivGSsN 100
                 +Kl++id++ ++vG+  
  EEA19731.1 912 EKLCIIDHTLAFVGGID 928
                 **************975 PP

  == domain 2  score: 27.9 bits;  conditional E-value: 3e-10
      PLDc_2    3 qliksAkksidiatyyf.............vsdreildallkaakrgvkvr..illdskkd.................................... 48  
                  +li+++++ ++i +++f                +++++++++a+++g + r  i+++  ++                                    
  EEA19731.1 1086 KLIEQSEHFVYIENQFFissceidgtkienLIGDALVERIIRASRNGENWRavIIIPL-IPgfqntvdseggtsvrlimqcqyrticrgetsifgrl 1181
                  5667777777777777744444444433333333347777777777766553233332.33666777777777777777776555555555555544 PP

      PLDc_2   49 ......dagavdeaslkelkellleagvevrvfetll.......gslHaKlylidgktvivGSsNltkrgl..dlnlElnvviedk 119 
                                   +++ + l++  ++      +         +HaK++++d++ +i+GS+N+++r++  +++ E++  + d 
  EEA19731.1 1182 raegieP--------EDYIQFFSLRTWGKIGP----NkqlvteqLYIHAKCMVVDDRAAIIGSANINERSMlgSRDSECAALVRDT 1255
                  3333321........22222222222222222....01223334689************************777777777777766 PP

>> PX  PX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.0   0.0     8e-12   4.8e-08       7     112 ..     447     637 ..     442     638 .. 0.93
   2 ?   -2.9   0.0       1.1   6.6e+03      42      64 ..     975     997 ..     973    1003 .. 0.89

  Alignments for each domain:
  == domain 1  score: 33.0 bits;  conditional E-value: 8e-12
                 EEEEEEEE..TTSSEEEEEEEEEETTS..SSEEEEEEEHHHHHHHHHHHHHHHT............TSTSTSSSTSGSSSSS................. CS
          PX   7 svlerets..gskkhsyylyevelktg..akewtvkRrYsdFeeLhskLlrkfp............rvkiPplPkkvlfgsv................. 72 
                 ++++++ +   +++h ++ +e e+++g  + +w ++R  +dF +Lh k + +              +  +P +P++  ++                   
  EEA19731.1 447 QITDSRFDshSGDRHLVFRIELEYGSGmtRMKWIIHRALRDFANLHLKYKLQIGtqkyiqlksqdsGHLLPRFPRSAFPYLRgvrgldsereeeeedgg 545
                 44444333348899999999****999*******************998888889999*******************99877***************** PP

                 ...................................................CTTSHHHHHHHHHHHHHHHHHHHTSCHHHH.SHHHHHHHHS CS
          PX  73 ...................................................rkkdeefiekrrkgLeeyLqrllnhpelrn.sevlteFLev 112
                                                                    + + ++  e++r++Le+yLq++++   +r+ s+ l +FLe 
  EEA19731.1 546 gyetgaevtsgnearrkmkkrrssfamtgrrsstgvtlendapagegaaaaTGERRSYSERQRRKLENYLQKMIRFLIFRPdSNRLCKFLEL 637
                 **************************************************98888999********************************96 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.1
                 HHHHHHHHHHHHHHTTSTSTSSS CS
          PX  42 sdFeeLhskLlrkfprvkiPplP 64 
                 +dF++L +  ++ ++r ++P +P
  EEA19731.1 975 QDFYDLDKPYEEMYDRNIVPRMP 997
                 79*****************9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1775 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       716  (0.0399353); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.93u 0.28s 00:00:01.21 Elapsed: 00:00:00.46
# Mc/sec: 11676.82
//
Query:       EEA19732.1  [L=361]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    0.00097   19.8   0.1     0.0012   19.5   0.1    1.3  1  Abhydrolase_6  Alpha/beta hydrolase family
     0.0035   16.7   0.0     0.0094   15.2   0.0    1.9  1  Hydrolase_4    Serine aminopeptidase, S33


Domain annotation for each model (and alignments):
>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.1   1.4e-07    0.0012      26     125 ..      88     219 ..      63     341 .. 0.58

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 1.4e-07
                    T...CEEEEE--TTSTS-GGCS..................--HHH.CHHHHHHHCCTT..........TTSEEEEEETCHHHHHHHHHHCC...EE CS
  Abhydrolase_6  26 g...vhvlapDlpGhGrsdppp..................ldled.ladlaalldelaa........gggpvvlvGHSlGGalalaaapla.lvvg 90 
                    +      +++D+++hG+++++                     ++  ++d++ l+d l+a        +    +++G SlGG+  ++++ +  ++ +
     EEA19732.1  88 RgliA--VTFDARNHGSRETDRlsnevwrtgnenhasdmfSVYSGtAEDISTLIDFLPAyifptsqhSIATHFALGISLGGHTTWLTLVHEpRITT 181
                    15432..67*******5544444444444444333333323333355999999999999999997654444499********99994444434334 PP

                    .EEES-.......----TTT......S----TTHHHHHHTT-CCCCH CS
  Abhydrolase_6  91 .vlldppp.....talpagl......laaalelllallallrllawl 125
                     v++ ++p     ++++a+l      l++  ++           ++l
     EEA19732.1 182 gVVIVGMPdyialMTDRARLsklstyLQPSDAPG---------SQFL 219
                    6999996655543222222233222211111111.........1222 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0     1e-06    0.0094      29     210 ..      87     287 ..      48     300 .. 0.67

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1e-06
  Hydrolase_4  29 aqGfavyalDhrGhGrse...........gkrghvpsfddy....vdDlaafvekv......keehpelplfllGhSmGGliallyllrypdkvagli 105
                  ++G   +++D+r hG  e           g+  h +++ ++     +D++++++ +       ++h+ + +f lG S+GG ++ l l ++p+  +g++
   EEA19732.1  87 KRGLIAVTFDARNHGSREtdrlsnevwrtGNENHASDMFSVysgtAEDISTLIDFLpayifpTSQHSIATHFALGISLGGHTTWLTLVHEPRITTGVV 184
                  567777777888888777778888887775555444433321111578888886652222224577778**********************9677*99 PP

  Hydrolase_4 106 lsaPalkikaklkappllklllkllgkllpklqvsnnlkadslsrdpevvaayeadplvhgkitvrlllelldamkrleeraakitlPllllhGeaDk 203
                  +++    i+ +++  +l kl   l  + +p  q+      ++ s+  evv++ +   +++g+i  +l ++ +++++  + +       +l ++G+ Dk
   EEA19732.1 185 IVGMPDYIALMTDRARLSKLSTYLQPSDAPGSQF--LGSRHFPSSLLEVVRKRDPAAFLTGGIPDSLPRDEYNLQSIETINRYLGGKRILCMSGATDK 280
                  9996655555444556666667777777777777..34566666666666666666666666666666666655444333334344566666666666 PP

  Hydrolase_4 204 vvdpeas 210
                  +v+++ +
   EEA19732.1 281 LVPYRLT 287
                  6666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (361 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       367  (0.0204696); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.24s 00:00:00.70 Elapsed: 00:00:00.39
# Mc/sec: 2780.58
//
Query:       EEA19733.1  [L=887]
Description: DNA helicase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.6e-56  190.5   0.0      8e-56  188.9   0.0    1.9  1  Helicase_C_2  Helicase C-terminal domain
    1.2e-51  174.8   1.0      3e-51  173.5   1.0    1.7  1  DEAD_2        DEAD_2
     0.0028   17.4   0.5     0.0074   16.0   0.0    1.9  2  HBB           Helical and beta-bridge domain
  ------ inclusion threshold ------
       0.56    9.6   4.5        1.1    8.7   0.5    3.0  3  DUF4349       Domain of unknown function (DUF4349)


Domain annotation for each model (and alignments):
>> Helicase_C_2  Helicase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  188.9   0.0   1.8e-59     8e-56       1     170 [.     657     865 ..     657     866 .. 0.90

  Alignments for each domain:
  == domain 1  score: 188.9 bits;  conditional E-value: 1.8e-59
  Helicase_C_2   1 llellevvpggvlvffpSyklleevverlke...........eleskkieifvee....keesrekvleeykek..kkkgaillavcrGklsEGidf 80 
                   ++++++v+p+gv+vffpSy++l++v +++++              +k ++i+ e+    ke++++++l ey++k  +++ga+ll+v++G+lsEGi+f
    EEA19733.1 657 IANICAVIPDGVVVFFPSYDYLNQVLNAWRKpnktggavsifAEIEKYKPIVYESnnhkKESNTDDTLLEYSKKveSGSGALLLSVVGGRLSEGINF 753
                   689****************************544444333332244444555555899888899********9556********************* PP

  Helicase_C_2  81 sddllraviivglPfpnpkdpeveakreyldekgk......................knsgkewylpealravnQaiGRliRhkdDygaivllDeRf 155
                   sd+l+r v+ivglPfpn+++  ++ak  +++++                        k +g++++++ ++ravnQ+iGR+iRh++Dy+aivl+D+R+
    EEA19733.1 754 SDKLGRGVLIVGLPFPNIHSAVWKAKIGHIEKQTYakltqnetelpvsrrreaetaaKAAGRDFFENSCMRAVNQCIGRAIRHRNDYAAIVLIDRRY 850
                   ********************************98899******************99999************************************* PP

  Helicase_C_2 156 akeeireklpkwlre 170
                   ++++i+ klp+w+r+
    EEA19733.1 851 ETQRIQGKLPTWIRQ 865
                   *************97 PP

>> DEAD_2  DEAD_2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  173.5   1.0   6.8e-55     3e-51       1     176 []     224     417 ..     224     417 .. 0.90

  Alignments for each domain:
  == domain 1  score: 173.5 bits;  conditional E-value: 6.8e-55
                 EEESSHHHHHHHHHHHHHHHHHCH......H...........HS---EEEE--CCCC-SCHHCCCHHCCCCHHHHHHHHHCCHHCCHTTTTTT-SCCCC CS
      DEAD_2   1 ycsRThsqleqvvkelkklesykk......k...........kekvkvviLgSRknlCineevkkekkekavneaCkelkkkkaeekeekCsffenlee 82 
                 ycsRThsql+q+ +el++++  ++      +           +e +k+++LgSRk+lCin++v++  + +a+ne+C+el+++ +++ +++Cs+  ++e+
  EEA19733.1 224 YCSRTHSQLSQFAQELRRVNLPSSlpslqeSaegekqehtelEEVIKHLTLGSRKQLCINPRVSNLGNATAINERCMELQQSGVAA-DKRCSYLPTKES 321
                 9*****************964443555555155666778888999**************************************876.999***988844 PP

                 HHHH...HHHHHHC---CHHHHHHHHHCT--HHHHHHHHHCCTSEEEEEHHHHTSCCCHHHHHT..GCGCEEEECTCCCHHHHHHHCC-EEEECHHH CS
      DEAD_2  83 lkkl...kkllleevvdiedlvelgeklklCPYylsrelledadiiilpYqyLldekireslkgislknsivilDEAhNiedvceeaasveiseesl 176
                    l   ++++l++v died++++g++l +CPYy++r+++++++ii+lpY +Ll+++ re+l+ +sl++ ivi+DEAhN+ d + +++sv+++ e+l
  EEA19733.1 322 EGMLfdfRDRVLSTVQDIEDISQVGKQLAICPYYAARKAIDQCEIITLPYPLLLQRSSREALD-LSLRDHIVIIDEAHNLMDAISNLHSVSVTLEQL 417
                 43336679******************************************************9.9***************************99886 PP

>> HBB  Helical and beta-bridge domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   0.5       2.6   1.1e+04       5      42 ..     107     144 ..     104     152 .. 0.73
   2 !   16.0   0.0   1.7e-06    0.0074      91     157 ..     532     599 ..     516     629 .. 0.83

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 2.6
                 HCCCCHHCCCCCCCHHHHHHHHHCCCCHHHHSTTTECC CS
         HBB   5 aketdepklqdeysrLvegLreaeeereeeyvleeepi 42 
                 ak++ ++ l ++ + L   L+++ +e+e+++ l+++  
  EEA19733.1 107 AKKERTQALTQKWRELEARLARIRKEEERRRKLAQNAA 144
                 77888888999999998999999888886666665544 PP

  == domain 2  score: 16.0 bits;  conditional E-value: 1.7e-06
                 HHHHHHHHHHHHTS.TTTEEEEEE.STT.EECCCCS-TCCHHH.HHHHCHCCCCCCTS-SSHHHHHHH CS
         HBB  91 lsrlaefllawlssdeedYvrlvskeegesLeavcldPskalr.flkerlssllmsgtltpleeysdi 157
                 l ++++f+l+ ++  +e  ++l + + g  L    ldP++++r  + e ++++l  gt++p+ +ysd 
  EEA19733.1 532 LFQVQSFILTLMNPSDEGQLFLNKADGGVLLRYLLLDPTSHFRdIVDEARTVILAGGTMSPMSDYSDH 599
                 457999**********************************997478999****************986 PP

>> DUF4349  Domain of unknown function (DUF4349)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.5   0.00024       1.1      77     114 ..     108     145 ..      96     150 .. 0.91
   2 ?   -1.6   0.0      0.35   1.6e+03      20      55 ..     192     227 ..     187     256 .. 0.72
   3 ?    0.3   0.0     0.087   3.9e+02      25      46 ..     498     519 ..     493     531 .. 0.71

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00024
     DUF4349  77 rstsaeDVTeqyvDleaRlkaleasedrllallekaks 114
                 ++++++ +T+++  leaRl+  +++e+r ++l ++a++
  EEA19733.1 108 KKERTQALTQKWRELEARLARIRKEEERRRKLAQNAAR 145
                 6789999**************************99976 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.35
     DUF4349  20 vaairelveeagGyvesssersgtegdersasltlR 55 
                  a+  +l ++++G+v  +++++g+++++ + ++  R
  EEA19733.1 192 SASTVALLDRFKGRVTGQKDNEGDNENQTRIYYCSR 227
                 677788999999***999977777777766666555 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.087
     DUF4349  25 elveeagGyvesssersgtegd 46 
                 +l+++++Gyve+ ++++g+ ++
  EEA19733.1 498 KLARKVDGYVENANNQDGKVNN 519
                 78999*********55544333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (887 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1030  (0.0574488); expected 358.6 (0.02)
Passed bias filter:                      534  (0.0297841); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.80u 0.26s 00:00:01.06 Elapsed: 00:00:00.46
# Mc/sec: 5767.03
//
Query:       EEA19734.1  [L=834]
Description: chitin synthase activator (Chs3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-20   72.8  21.0    1.9e-07   31.5   0.0    7.1  6  Sel1      Sel1 repeat
     0.0064   16.3   0.6       0.05   13.4   0.0    2.8  3  TPR_1     Tetratricopeptide repeat
  ------ inclusion threshold ------
        1.6    9.0   0.0        1.6    9.0   0.0    3.9  4  TPR_2     Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> Sel1  Sel1 repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.2   9.2e-05      0.55       8      38 .]     227     256 ..     220     256 .. 0.89
   2 !    4.9   0.0    0.0078        46       2      34 ..     258     284 ..     257     288 .. 0.74
   3 !   21.7   0.5     4e-08   0.00024       1      34 [.     289     321 ..     289     322 .. 0.92
   4 !    5.6   1.1    0.0047        28       1      37 [.     373     408 ..     373     409 .. 0.90
   5 !    8.1   0.0   0.00073       4.4       2      37 ..     411     446 ..     410     447 .. 0.78
   6 !   31.5   0.0   3.2e-11   1.9e-07       2      38 .]     449     483 ..     448     483 .. 0.93

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 9.2e-05
        Sel1   8 GmfylylnGl.gvpkDpekAiewyekAAeqGd 38 
                 Gm++  ++G+ g   D+++A++ y +AAe+G+
  EEA19734.1 227 GMWL--EFGKfGYRVDKKEAFRSYSRAAEKGY 256
                 8888..****77999***************96 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.0078
        Sel1   2 eAmyrLGmfylylnGlgvpkDpekAiewyekAA 34 
                  A yr+G ++  ++       p kAi++yek  
  EEA19734.1 258 RAEYRMG-MQ--FESS---NEPAKAIRHYEKGV 284
                 6999999.56..7774...3477*******975 PP

  == domain 3  score: 21.7 bits;  conditional E-value: 4e-08
        Sel1   1 aeAmyrLGmfylylnGl.gvpkDpekAiewyekAA 34 
                 ++++yrLGm+   l G+ g  +D+ek++e+ ++AA
  EEA19734.1 289 SASYYRLGMMI--LLGQhGQRQDYEKGLEYIRLAA 321
                 689*****777..****999**************9 PP

  == domain 4  score: 5.6 bits;  conditional E-value: 0.0047
        Sel1   1 aeAmyrLGmfylylnGl.gvpkDpekAiewyekAAeqG 37 
                 a A+ ++G   +y+ G+ g + Dp + +++  +AA+qG
  EEA19734.1 373 AKAQVKMG--AAYELGQlGCEFDPALSLHYNALAARQG 408
                 689*****..777****77888**************99 PP

  == domain 5  score: 8.1 bits;  conditional E-value: 0.00073
        Sel1   2 eAmyrLGmfylylnGl.g.vpkDpekAiewyekAAeqG 37 
                 eA ++     ++l G  g  +k+ e A+ + ++AA+ G
  EEA19734.1 411 EAEMAIS--KWFLCGHeGlFEKNDETAFTYAQRAAQSG 446
                 6666666..6777777765778*************987 PP

  == domain 6  score: 31.5 bits;  conditional E-value: 3.2e-11
        Sel1   2 eAmyrLGmfylylnGlgvpkDpekAiewyekAAeqGd 38 
                  A ++LG  y+y+ G  vp D+++A++wy kAA+ G+
  EEA19734.1 449 TAEFALG--YFYEVGIHVPVDIQEARRWYAKAAASGN 483
                 699****..777**********************997 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.0   8.3e-06      0.05       1      28 [.     257     284 ..     257     288 .. 0.93
   2 ?   -3.0   0.0       1.3   7.6e+03       3       9 ..     291     297 ..     290     298 .. 0.77
   3 ?   -1.6   0.1      0.46   2.7e+03      14      23 ..     307     316 ..     304     322 .. 0.65

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 8.3e-06
                 HHHHHHHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_1   1 akalynlGnayfklgkydeAleyyekAL 28 
                 a+a y++G+ + + +++ +A+ +yek +
  EEA19734.1 257 ARAEYRMGMQFESSNEPAKAIRHYEKGV 284
                 7999*********************976 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.3
                 HHHHHHH CS
       TPR_1   3 alynlGn 9  
                 ++y+lG+
  EEA19734.1 291 SYYRLGM 297
                 6999996 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 0.46
                 TT-HHHHHHH CS
       TPR_1  14 lgkydeAley 23 
                  ++y++ ley
  EEA19734.1 307 RQDYEKGLEY 316
                 5566666666 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.3       1.5   8.7e+03      17      29 ..     241     253 ..     240     254 .. 0.84
   2 ?    9.0   0.0   0.00027       1.6       2      28 ..     258     284 ..     257     288 .. 0.89
   3 ?   -0.1   0.1      0.23   1.4e+03      13      29 ..     306     322 ..     304     327 .. 0.79
   4 ?    1.1   0.4     0.092   5.5e+02      16      28 ..     467     479 ..     467     481 .. 0.86

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 1.5
       TPR_2  17 yeeAleafekAle 29 
                  +eA + + +A e
  EEA19734.1 241 KKEAFRSYSRAAE 253
                 689*9****9987 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00027
       TPR_2   2 ealynlGlayyklgdyeeAleafekAl 28 
                 +a y++G+  + ++++++A++++ek +
  EEA19734.1 258 RAEYRMGMQFESSNEPAKAIRHYEKGV 284
                 6679********************976 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.23
       TPR_2  13 klgdyeeAleafekAle 29 
                 +++dye+ le+ + A +
  EEA19734.1 306 QRQDYEKGLEYIRLAAQ 322
                 57899999999998877 PP

  == domain 4  score: 1.1 bits;  conditional E-value: 0.092
       TPR_2  16 dyeeAleafekAl 28 
                 d +eA++++ kA 
  EEA19734.1 467 DIQEARRWYAKAA 479
                 579********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (834 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       512  (0.0285571); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.69u 0.30s 00:00:00.99 Elapsed: 00:00:00.48
# Mc/sec: 5198.15
//
Query:       EEA19735.1  [L=147]
Description: TBP interacting domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.086   12.9   1.3       0.19   11.8   1.3    1.6  1  Med9      RNA polymerase II transcription mediator complex su
       0.25   11.7   1.8       0.44   10.9   0.1    2.0  2  TSC22     TSC-22/dip/bun family
       0.51   10.5   2.9        6.3    7.0   0.5    2.2  2  bZIP_1    bZIP transcription factor


Domain annotation for each model (and alignments):
>> Med9  RNA polymerase II transcription mediator complex subunit 9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   1.3   3.2e-05      0.19       7      65 ..       3      69 ..       1      86 [. 0.73

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3.2e-05
        Med9  7 ydilksi.ekdp........nlsskdletktgelrhkLkkarelirelpgidrsveeqeaeieeleeq 65
                y++++++  +d+        n+ +kd+e k++ l+ + k  re ++++  +   +   +++i++lee+
  EEA19735.1  3 YHAIQQVdANDTtgtkgrdpNQPTKDFEEKISVLKIREKDLREKLATINAV-IPIPILKDQIANLEEK 69
                667777753333555555669**************************9874.4566666666666654 PP

>> TSC22  TSC-22/dip/bun family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.2      0.25   1.5e+03      14      31 ..      31      48 ..      27      52 .. 0.70
   2 ?   10.9   0.1   7.3e-05      0.44      18      43 ..      58      83 ..      56      88 .. 0.87

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.25
       TSC22 14 EeVevLkekIkeLeerns 31
                E + vLk + k+L e+ +
  EEA19735.1 31 EKISVLKIREKDLREKLA 48
                667777777778877765 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 7.3e-05
       TSC22 18 vLkekIkeLeernseleeENslLkal 43
                +Lk++I++Lee+ + l ++ s+L a 
  EEA19735.1 58 ILKDQIANLEEKKALLSSQVSTLSAE 83
                7****************999998765 PP

>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.1     0.012        70      29      53 ..      27      51 ..      23      54 .. 0.86
   2 ?    7.0   0.5    0.0011       6.3      26      54 ..      61      89 ..      59      93 .. 0.83

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.012
                HHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1 29 eeLerrvkaLekeNksLkseleelk 53
                +  e++ ++L+   k+L+++l +++
  EEA19735.1 27 KDFEEKISVLKIREKDLREKLATIN 51
                67799***************98875 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0011
                HHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1 26 aeieeLerrvkaLekeNksLkseleelkk 54
                 +i++Le++ + L+++ ++L+ e+++ ++
  EEA19735.1 61 DQIANLEEKKALLSSQVSTLSAEMQKSSD 89
                57899999999999999999999988776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (147 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       815  (0.0454571); expected 358.6 (0.02)
Passed bias filter:                      522  (0.0291148); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.41
# Mc/sec: 1084.05
//
Query:       EEA19736.1  [L=602]
Description: spindle poison sensitivity protein Scp3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.6e-11   43.1   9.3    2.7e-06   27.1   1.9    2.5  2  zf-CCCH    Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    7.3e-10   38.4   9.3    4.1e-06   26.5   2.2    2.5  2  zf-CCCH_4  CCCH-type zinc finger
    8.6e-09   35.2  16.4    4.7e-05   23.3   1.8    2.4  2  zf_CCCH_4  Zinc finger domain
      2e-08   34.9   5.2    0.00088   19.9   0.3    2.7  2  Torus      Torus domain
    1.1e-05   25.6   0.1    2.4e-05   24.5   0.1    1.5  1  zf-CCCH_3  Zinc-finger containing family
     0.0087   16.5  14.1        0.2   12.2   3.2    2.4  2  zf-CCCH_2  RNA-binding, Nab2-type zinc finger


Domain annotation for each model (and alignments):
>> zf-CCCH  Zinc finger C-x8-C-x5-C-x3-H type (and similar)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.1   1.9   9.2e-10   2.7e-06       2      26 ..      56      79 ..      55      80 .. 0.93
   2 !   19.9   0.9   1.7e-07    0.0005       4      25 ..      87     107 ..      85     108 .. 0.87

  Alignments for each domain:
  == domain 1  score: 27.1 bits;  conditional E-value: 9.2e-10
                HCHCBCHHHHHS--TTGGG-SSBSC CS
     zf-CCCH  2 ktelCrffmrtGyCkyGdrCkFaHg 26
                k+++C+ff++ G+C+ G++C+F H+
  EEA19736.1 56 KHVPCKFFRQ-GACQAGPACPFLHS 79
                889***9999.*************8 PP

  == domain 2  score: 19.9 bits;  conditional E-value: 1.7e-07
                 HCBCHHHHHS--TTGGG-SSBS CS
     zf-CCCH   4 elCrffmrtGyCkyGdrCkFaH 25 
                 ++C++f + G Ck+G++C  aH
  EEA19736.1  87 APCKYFTK-GNCKFGAKCALAH 107
                 79******.*********7555 PP

>> zf-CCCH_4  CCCH-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.7   2.8e-06    0.0083       1      21 [.      58      78 ..      58      79 .. 0.96
   2 !   26.5   2.2   1.4e-09   4.1e-06       2      21 ..      88     107 ..      87     107 .. 0.95

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 2.8e-06
   zf-CCCH_4  1 rlCpyfakGsCrfGdnCrFsH 21
                ++C++f +G C  G+ C F+H
  EEA19736.1 58 VPCKFFRQGACQAGPACPFLH 78
                69******************* PP

  == domain 2  score: 26.5 bits;  conditional E-value: 1.4e-09
   zf-CCCH_4   2 lCpyfakGsCrfGdnCrFsH 21 
                 +C+yf+kG+C+fG +C  +H
  EEA19736.1  88 PCKYFTKGNCKFGAKCALAH 107
                 9***************9998 PP

>> zf_CCCH_4  Zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.3   1.8   1.6e-08   4.7e-05       1      19 []      60      78 ..      60      78 .. 1.00
   2 !   17.1   7.1   1.4e-06    0.0043       1      15 [.      89     103 ..      89     104 .. 0.98

  Alignments for each domain:
  == domain 1  score: 23.3 bits;  conditional E-value: 1.6e-08
   zf_CCCH_4  1 CkfflqGtCkkGdkCrFaH 19
                Ckff qG C+ G +C+F+H
  EEA19736.1 60 CKFFRQGACQAGPACPFLH 78
                ******************* PP

  == domain 2  score: 17.1 bits;  conditional E-value: 1.4e-06
   zf_CCCH_4   1 CkfflqGtCkkGdkC 15 
                 Ck+f +G+Ck+G+kC
  EEA19736.1  89 CKYFTKGNCKFGAKC 103
                 *************** PP

>> Torus  Torus domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.4   2.4e-06    0.0071      65      93 ..      52      80 ..      41      88 .. 0.86
   2 !   19.9   0.3   2.9e-07   0.00088      69      98 ..      85     114 ..      79     120 .. 0.84

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 2.4e-06
                HHSTT--B-HHHHHT--SSGGG-SSB-S- CS
       Torus 65 dkekesyfClfFarGlCakGkkCeylHrl 93
                +k+++++ C fF +G C+ G  C +lH+ 
  EEA19736.1 52 TKNTKHVPCKFFRQGACQAGPACPFLHST 80
                56778899*******************75 PP

  == domain 2  score: 19.9 bits;  conditional E-value: 2.9e-07
                 T--B-HHHHHT--SSGGG-SSB-S---SS- CS
       Torus  69 esyfClfFarGlCakGkkCeylHrlPteed 98 
                 +s  C +F++G C+ G+kC+  H lP+ + 
  EEA19736.1  85 DSAPCKYFTKGNCKFGAKCALAHILPDGRR 114
                 5678**********************8765 PP

>> zf-CCCH_3  Zinc-finger containing family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.5   0.1   8.2e-09   2.4e-05       5      75 ..      57     128 ..      53     158 .. 0.86

  Alignments for each domain:
  == domain 1  score: 24.5 bits;  conditional E-value: 8.2e-09
   zf-CCCH_3   5 gddcyffyystctkGdscpfrheeaalGsetvctlWqegrc.lrevckfrhmeidkkrkeipcywenqpaGc 75 
                    c ff    c+ G  cpf h+  a      c+++ +g+c + ++c + h+  d +r + p y  + ++G 
  EEA19736.1  57 HVPCKFFRQGACQAGPACPFLHSTDAAIDSAPCKYFTKGNCkFGAKCALAHILPDGRRVNRPNYGGQGAGGG 128
                 557*******************9988889999*********6789*******99999999999977766665 PP

>> zf-CCCH_2  RNA-binding, Nab2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.2   3.2   6.7e-05       0.2       1      17 [.      59      78 ..      59      78 .. 0.98
   2 !    9.7   3.3    0.0004       1.2       1      14 [.      88     104 ..      88     107 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 6.7e-05
   zf-CCCH_2  1 pCrffpn..C.tnpkCpFaH 17
                pC+ff    C  +p CpF H
  EEA19736.1 59 PCKFFRQgaCqAGPACPFLH 78
                9*****************99 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.0004
   zf-CCCH_2   1 pCrffpn..C.tnpkCp 14 
                 pC++f +  C +++kC 
  EEA19736.1  88 PCKYFTKgnCkFGAKCA 104
                 9***************5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (602 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       918  (0.051202); expected 358.6 (0.02)
Passed bias filter:                      334  (0.018629); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.70u 0.32s 00:00:01.02 Elapsed: 00:00:00.54
# Mc/sec: 3362.01
//
Query:       EEA19737.1  [L=968]
Description: RSC complex subunit (RSC1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      3e-38  129.8   7.3    4.4e-19   68.3   1.1    2.5  2  Bromodomain  Bromodomain
    1.2e-18   67.1   0.9    3.4e-18   65.6   0.9    1.8  1  BAH          BAH domain
    0.00039   18.9   4.4    0.00039   18.9   4.4    2.1  2  CDC45        CDC45-like protein
  ------ inclusion threshold ------
       0.17   11.5   1.7       0.35   10.4   1.7    1.4  1  GCIP         Grap2 and cyclin-D-interacting


Domain annotation for each model (and alignments):
>> Bromodomain  Bromodomain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.3   1.1   9.7e-23   4.4e-19      12      82 ..     106     176 ..      94     178 .. 0.94
   2 !   64.4   0.6   1.7e-21   7.4e-18      13      83 ..     298     368 ..     283     369 .. 0.92

  Alignments for each domain:
  == domain 1  score: 68.3 bits;  conditional E-value: 9.7e-23
                  TCGGGGCSTT-GCCSTTHHHH.SS---HHHHHHHHHTT--SSHHHHHHHHHHHHHHHHHHSHTTSHHHHHH CS
  Bromodomain  12 klaepFlepvdpeefpdyyavikkPldLstIkkklesnkYksladfeadlkllfsNarkyngegsviyela 82 
                  ++++ F++ v+++ +pdyy++ik+P+ Ls +k+k+++++Y+++++f  d+ l+ +Na++yn+++s+ y +a
   EEA19737.1 106 DPSRLFHRSVNKRYVPDYYDIIKEPMALSILKQKINKREYTKFEQFVRDCALITHNAQTYNRPESQAYRDA 176
                  48899***************************************************************998 PP

  == domain 2  score: 64.4 bits;  conditional E-value: 1.7e-21
                  CGGGGCSTT-GCCSTTHHHH.SS---HHHHHHHHHTT--SSHHHHHHHHHHHHHHHHHHSHTTSHHHHHHH CS
  Bromodomain  13 laepFlepvdpeefpdyyavikkPldLstIkkklesnkYksladfeadlkllfsNarkyngegsviyelae 83 
                    ++F++ +d++ +pdy+  i++P+ +  Ik+k +++kY+s++ f+ d+  +f+Na+ yn+++s+iy++ae
   EEA19737.1 298 KVRHFERLPDKAMYPDYFMEIREPMAIDSIKRKSKRKKYHSVDHFMRDVDTMFNNAKSYNEPNSQIYKDAE 368
                  6789*****************************************************************98 PP

>> BAH  BAH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.6   0.9   7.7e-22   3.4e-18       4     122 .]     410     526 ..     407     526 .. 0.96

  Alignments for each domain:
  == domain 1  score: 65.6 bits;  conditional E-value: 7.7e-22
                 ETTGEEEEEETTSTTEEEEEEEEEEEEETTSTCEEEEEEEEEEECGGGS.TTTTHCCCTTEEEEEEEEEEEEGGGEEEEEEEEEHHHHCTECCHCHHCS CS
         BAH   4 avGdfVyfddtstdepyqirrIeeLkenakneeaeatvlvdwflrpeet.ksalklrqkrElfltrqseilplaairgkcrVvllsdleeaqnylpkkl 101
                 +vGd+V +++ ++  ++ +++I + ++++  e   ++v+++w++rpe+t +  +k ++++E+  t q+ ++ +++++ +c V+ +++++  +++    +
  EEA19737.1 410 KVGDWVHIQNPNDVTKPIVAQIYRTWQDSEGE---KWVNACWYYRPEQTvHHFEKHFYPNEVVKTGQYRDHRIDEVIDRCFVMFFTRYNRGRPRGFPLD 505
                 79**********9******************9...***********************************************************95556 PP

                 TTEEEEEEEEETTTTEEEE-S CS
         BAH 102 ddtFycslvydptaktfkkdk 122
                 +++++c+  y++++ +++k+k
  EEA19737.1 506 KEIYVCEARYNEEKHKLNKIK 526
                 779**************9987 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   4.4   8.7e-08   0.00039     138     242 ..     218     371 ..     173     377 .. 0.66
   2 ?   -0.4   5.1      0.06   2.7e+02     162     225 ..     837     901 ..     821     937 .. 0.63

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 8.7e-08
       CDC45 138 eeeeeddddeeeeeeeeedeedeeedeeeskkkrksksdeeeesddddersrkrrrse......................................... 195
                 e+    ddde++e ++e+de+d+++d++ ++++r+    ++++s+++d++ rk+r +                                          
  EEA19737.1 218 ED----DDDEDDE-DDEDDEDDDSDDGDGRRRRRR-GPGRKNASQNQDQEVRKKRGRPprvdtpmearikavlkglrkfkdnsgqlkvrhferlpdkam 310
                 11....1111112.112222222222322222222.333333333333333433333347789999999999*************************** PP

       CDC45 196 ...............psakklrrqlkkerrkyeavlekyysqgtsygesvsslmYsLaselg 242
                                + ++k++r++ +  ++  + +++ +++ +sy e+ s ++Y+ a++l+
  EEA19737.1 311 ypdyfmeirepmaidSIKRKSKRKKYHSVDHFMRDVDTMFNNAKSYNEPNS-QIYKDAEDLQ 371
                 *******99999887666777777778888888899999********9987.5676666665 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.06
       CDC45 162 edeeeskkkrksksdeeee..sddddersrkrrrsepsakklrrqlkkerrkyeavlekyysqgts 225
                 ++ee++k++r+++++++++    d+de++ kr r + +++   ++l+++ +k  + l+k+ ++gts
  EEA19737.1 837 AREEQRKRRREEEQQRQQDamAIDTDEQQPKRPRLD-TETVNPSRLNNLISKTVSLLAKNITTGTS 901
                 344444455554444444456556666677777777.33444444666666666666666666665 PP

>> GCIP  Grap2 and cyclin-D-interacting
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   1.7   7.8e-05      0.35     130     178 ..     178     262 ..     171     308 .. 0.65

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 7.8e-05
                 HHHHH.HHHHHHHHHH...............................S-------------........-----TTS--HHHHHH CS
        GCIP 130 lvkDa.leEmkellee...........................edeeedededdldddede........ergnqdrklseeekev 178
                 ++kD+ + E+k+l+e                            +de+ + dedd+ddd d+        ++  +++  +++++ev
  EEA19737.1 178 VIKDVfIGEFKKLVESgiitaeaaempdlgeipeadplpieddDDEDDEDDEDDEDDDSDDgdgrrrrrRGPGRKNASQNQDQEV 262
                 6777634677777777777777777778888888899999754333333344444555444888888874444444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (968 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1624  (0.0905795); expected 358.6 (0.02)
Passed bias filter:                      595  (0.0331865); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.05u 0.38s 00:00:01.43 Elapsed: 00:00:00.59
# Mc/sec: 4953.19
//
Query:       EEA19738.1  [L=335]
Description: OTU-like cysteine protease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      6e-06   26.8   0.0    9.9e-06   26.1   0.0    1.3  1  OTU       OTU-like cysteine protease


Domain annotation for each model (and alignments):
>> OTU  OTU-like cysteine protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.1   0.0   5.5e-10   9.9e-06       3      84 ..     140     217 ..     138     248 .. 0.81

  Alignments for each domain:
  == domain 1  score: 26.1 bits;  conditional E-value: 5.5e-10
                 SS-HHHHHHHHCCCSS.SHCCHHHHHHHHHCHHHHHHTSSHHCCHHHHCCHHH.HHHHTTSTTHHHHHHHHHHHHHHCTS-EE CS
         OTU   3 DGnCLlravsqqlwgvsdelrkakvseLreklaeylrehseelelfleeeeeg.ylkeiektaawggeleifalahiLrrpIi 84 
                 D  CL+rav  +++     +  ++  eLr+ +a+ ++ + + ++ ++ e++   y++ i+++  wgg +e+ +l++ + + I 
  EEA19738.1 140 DNSCLFRAVGGAIM-----GGMDTMTELRSIVAQTIQAQPDVYSDVVLEKKRDdYCRWIQSENSWGGGIELSILSKHFGVEIC 217
                 557**********9.....55567788**********99999887665554435**********************9998885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (335 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       992  (0.0553294); expected 358.6 (0.02)
Passed bias filter:                      743  (0.0414412); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.73u 0.37s 00:00:01.10 Elapsed: 00:00:00.58
# Mc/sec: 1744.21
//
Query:       EEA19739.1  [L=439]
Description: oxysterol binding protein (Orp8), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.6e-54  183.4   0.3    1.4e-44  152.5   0.0    2.2  2  Oxysterol_BP  Oxysterol-binding protein


Domain annotation for each model (and alignments):
>> Oxysterol_BP  Oxysterol-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  152.5   0.0   7.9e-49   1.4e-44       3     272 ..      22     358 ..      20     368 .. 0.81
   2 !   25.5   3.9   2.9e-10   5.2e-06     318     356 ..     366     405 ..     360     424 .. 0.82

  Alignments for each domain:
  == domain 1  score: 152.5 bits;  conditional E-value: 7.9e-49
                   HCCHTTSTT.-BCCCS..---GGGEEEEEHHHHHHHCCTTCHHHHHHHC.SSHHHHHHHHHHHHHHCCCGCTSTSSSEEE---TT-EEEEEETTCEE CS
  Oxysterol_BP   3 wsilkkciG.kDLski..slPvffneplSlLqrlaedleyselLdkaakeddsleRlayVaaFalSsyastikrrlkKPFNPlLGEtfelvredkgf 96 
                   +sil+k +G  D+ ++  slP +++ep+  L+ + ++l  +e++ ++ ++dd+l R++ V++F++++  ++ik++ +KP+N  LGE f+ ++e  ++
    EEA19739.1  22 LSILRKFVGvADIASVrfSLPAQLLEPTPNLE-YWNYLDRPETFASIGTSDDDLGRMLEVLRFWFTKDLKYIKGKPCKPYNSTLGEFFRAYWEVDNT 117
                   7999999995589877669************9.789********************************************************66444 PP

                   ........................EEEEEEEETTTTEEEEEEEE..CTEEEEEEEEEEEEE-SSEEEEEE-SE...EEEEEEEESEEEEEEE--EEE CS
  Oxysterol_BP  97 ........................rfiaEQVsHhPpvsAfhaes..egweldgeikvkskflgkslevkpeGt...ahlellkksgehYtwtkptti 164
                                            f++EQ+sHhPpvsAf++++  +g++ +g  +++ kf+g+s++v p  +   ++++l ++++e+Y++t+p ++
    EEA19739.1 118 aapvlpsskptngavsttdgsakvCFLTEQTSHHPPVSAFYIDCpqRGVSARGFDQISAKFTGTSIRVGPGQHnlgIFVNLANRDNEEYQLTHPAAH 214
                   456666666677777777777777********************9999********************9933211145666799************* PP

                   EE-TTTTS-EEEEEEEEEEEETTT--EEEEEEE---SSS---SSEEEEEEEE..............TTS-EEEEEEEETTTEEEE...........E CS
  Oxysterol_BP 165 vhniivgklwvelsgeveitnhstgdkakleFkkkglfsskksnkvegkvkd..............kkkevlyeisGkwdeelyi...........k 236
                   +++++ g+l++ + ++++it  +t  k++l++ + g++ sk++ +veg++++               +++vl++i+G w e++y+           +
    EEA19739.1 215 LSGLLRGSLYISVADSCYITCPKTRIKVILQYLEDGWV-SKAHSRVEGVIFRydpdndtkmkvkdvPSNDVLARINGCWREQIYYtltaaatsgsgS 310
                   ********************999***************.59999**999986667778888887788899***************666655444441 PP

                   ETTSTTS--EEEEETT...................-....BSXXGCGSSTTBCCCCCCH CS
  Oxysterol_BP 237 kkktekkeeeedasek...................s....kvkekeeqeefeseklWka 272
                              ++s++                   +    +v ++e q ++es+k W+ 
    EEA19739.1 311 -----------SISSRssttsefnkpqllidlvplTivpkSVPPEEIQLSNESRKFWSG 358
                   ...........333222222223333344445544145557777778888888888875 PP

  == domain 2  score: 25.5 bits;  conditional E-value: 2.9e-10
                   T-HHHHHHHHHHHHHHHHHHHHHHCCTT.----SSEEEEE CS
  Oxysterol_BP 318 gdideAeeeKkrlEekQRerrkereekk.ewkpkwFekek 356
                   +++ +A++ K+++Ee+QR++++ere+k+ +wkp++F+   
    EEA19739.1 366 KQFGQATKLKQEIEERQRAKAAEREAKSeKWKPRFFTDAV 405
                   67889*******************665537******9776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (439 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       588  (0.032796); expected 358.6 (0.02)
Passed bias filter:                      469  (0.0261587); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.70u 0.40s 00:00:01.10 Elapsed: 00:00:00.59
# Mc/sec: 2241.63
//
Query:       EEA19740.1  [L=439]
Description: oxysterol binding protein (Orp8), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.6e-54  183.4   0.3    1.4e-44  152.5   0.0    2.2  2  Oxysterol_BP  Oxysterol-binding protein


Domain annotation for each model (and alignments):
>> Oxysterol_BP  Oxysterol-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  152.5   0.0   7.9e-49   1.4e-44       3     272 ..      22     358 ..      20     368 .. 0.81
   2 !   25.5   3.9   2.9e-10   5.2e-06     318     356 ..     366     405 ..     360     424 .. 0.82

  Alignments for each domain:
  == domain 1  score: 152.5 bits;  conditional E-value: 7.9e-49
                   HCCHTTSTT.-BCCCS..---GGGEEEEEHHHHHHHCCTTCHHHHHHHC.SSHHHHHHHHHHHHHHCCCGCTSTSSSEEE---TT-EEEEEETTCEE CS
  Oxysterol_BP   3 wsilkkciG.kDLski..slPvffneplSlLqrlaedleyselLdkaakeddsleRlayVaaFalSsyastikrrlkKPFNPlLGEtfelvredkgf 96 
                   +sil+k +G  D+ ++  slP +++ep+  L+ + ++l  +e++ ++ ++dd+l R++ V++F++++  ++ik++ +KP+N  LGE f+ ++e  ++
    EEA19740.1  22 LSILRKFVGvADIASVrfSLPAQLLEPTPNLE-YWNYLDRPETFASIGTSDDDLGRMLEVLRFWFTKDLKYIKGKPCKPYNSTLGEFFRAYWEVDNT 117
                   7999999995589877669************9.789********************************************************66444 PP

                   ........................EEEEEEEETTTTEEEEEEEE..CTEEEEEEEEEEEEE-SSEEEEEE-SE...EEEEEEEESEEEEEEE--EEE CS
  Oxysterol_BP  97 ........................rfiaEQVsHhPpvsAfhaes..egweldgeikvkskflgkslevkpeGt...ahlellkksgehYtwtkptti 164
                                            f++EQ+sHhPpvsAf++++  +g++ +g  +++ kf+g+s++v p  +   ++++l ++++e+Y++t+p ++
    EEA19740.1 118 aapvlpsskptngavsttdgsakvCFLTEQTSHHPPVSAFYIDCpqRGVSARGFDQISAKFTGTSIRVGPGQHnlgIFVNLANRDNEEYQLTHPAAH 214
                   456666666677777777777777********************9999********************9933211145666799************* PP

                   EE-TTTTS-EEEEEEEEEEEETTT--EEEEEEE---SSS---SSEEEEEEEE..............TTS-EEEEEEEETTTEEEE...........E CS
  Oxysterol_BP 165 vhniivgklwvelsgeveitnhstgdkakleFkkkglfsskksnkvegkvkd..............kkkevlyeisGkwdeelyi...........k 236
                   +++++ g+l++ + ++++it  +t  k++l++ + g++ sk++ +veg++++               +++vl++i+G w e++y+           +
    EEA19740.1 215 LSGLLRGSLYISVADSCYITCPKTRIKVILQYLEDGWV-SKAHSRVEGVIFRydpdndtkmkvkdvPSNDVLARINGCWREQIYYtltaaatsgsgS 310
                   ********************999***************.59999**999986667778888887788899***************666655444441 PP

                   ETTSTTS--EEEEETT...................-....BSXXGCGSSTTBCCCCCCH CS
  Oxysterol_BP 237 kkktekkeeeedasek...................s....kvkekeeqeefeseklWka 272
                              ++s++                   +    +v ++e q ++es+k W+ 
    EEA19740.1 311 -----------SISSRssttsefnkpqllidlvplTivpkSVPPEEIQLSNESRKFWSG 358
                   ...........333222222223333344445544145557777778888888888875 PP

  == domain 2  score: 25.5 bits;  conditional E-value: 2.9e-10
                   T-HHHHHHHHHHHHHHHHHHHHHHCCTT.----SSEEEEE CS
  Oxysterol_BP 318 gdideAeeeKkrlEekQRerrkereekk.ewkpkwFekek 356
                   +++ +A++ K+++Ee+QR++++ere+k+ +wkp++F+   
    EEA19740.1 366 KQFGQATKLKQEIEERQRAKAAEREAKSeKWKPRFFTDAV 405
                   67889*******************665537******9776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (439 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       588  (0.032796); expected 358.6 (0.02)
Passed bias filter:                      469  (0.0261587); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.31s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 2985.80
//
Query:       EEA19741.1  [L=1182]
Description: condensin complex component cnd1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.1e-62  208.6   0.4    1.6e-61  207.0   0.4    1.9  1  Cnd1_N        non-SMC mitotic condensation complex subunit 1,
    2.7e-49  167.3   3.3    7.6e-44  149.6   0.9    3.8  3  Cnd1          non-SMC mitotic condensation complex subunit 1
    9.1e-12   45.2   3.7    3.1e-05   24.3   0.0    5.3  5  HEAT_2        HEAT repeats
    1.4e-09   37.4   9.1      0.058   13.7   0.0    6.6  6  HEAT          HEAT repeat
    4.3e-07   28.9   5.6       0.18   10.3   0.1    4.3  3  Adaptin_N     Adaptin N terminal region
    1.9e-05   24.8   0.3       0.21   11.8   0.0    4.1  3  RTP1_C1       Required for nuclear transport of RNA pol II C-
    0.00042   19.6   4.5    0.00084   18.6   0.8    3.3  3  Cnd3          Nuclear condensing complex subunits, C-term dom
    0.00087   19.7  10.6       0.32   11.6   0.0    5.6  6  HEAT_EZ       HEAT-like repeat
  ------ inclusion threshold ------
       0.11   12.9   1.9        7.1    7.0   0.0    4.2  5  Cohesin_HEAT  HEAT repeat associated with sister chromatid co


Domain annotation for each model (and alignments):
>> Cnd1_N  non-SMC mitotic condensation complex subunit 1, N-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  207.0   0.4     8e-65   1.6e-61       2     166 .]      87     250 ..      86     250 .. 0.95

  Alignments for each domain:
  == domain 1  score: 207.0 bits;  conditional E-value: 8e-65
      Cnd1_N   2 klksklldlllsglsallesvesdlessdeadsvashknaLemygfllqwlvealekessskssaasasargrkkk.kkkkkkkeeawdweaqrerile 99 
                 k++sk+ldl++sgl+++++ ++ dle +de+++v++hk++Lemygfllqw ++a+e ++++k+++a++++  ++k+ k+k+++ke++wdw++q++  +e
  EEA19741.1  87 KSLSKILDLIVSGLAVEADIIHCDLE-ADEQEAVQQHKQLLEMYGFLLQWALSAVEVKAAEKPATAAPAR-RTGKSgKSKQSAKEGNWDWTPQIQISME 183
                 7899**********************.788***********************************99885.4455557********************* PP

      Cnd1_N 100 liakvlelklsrlfqttserdeFislftrpaysllEneallKdksirdaifkvlclavkkhghalaa 166
                 +++kvl+lkl ++f tts+rd+F++lftr +y l+Ene+++K+ +ir+++fkvlc+avk+hgha++a
  EEA19741.1 184 TMCKVLKLKLGKIFLTTSDRDTFVNLFTRSVYLLFENEQRVKNMAIRMHAFKVLCIAVKHHGHAFGA 250
                 ****************************************************************986 PP

>> Cnd1  non-SMC mitotic condensation complex subunit 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   1.2e-05     0.024      19      87 ..     370     441 ..     366     452 .. 0.87
   2 ?   -0.1   0.0      0.44   8.7e+02      33      57 ..     957     983 ..     955     996 .. 0.85
   3 !  149.6   0.9   3.8e-47   7.6e-44       1     162 []     998    1158 ..     998    1158 .. 0.98

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.2e-05
        Cnd1  19 veylvepLrkrLkDedpyVRktaaivvakL..ilndmvkekgflsel.aklleDenprVvanalaalteise 87 
                 + ++ + L++r+ D +py R  a+ v  +L  +++++ k ++  +el a+ leD++++V+ na+ +l  + +
  EEA19741.1 370 INAFFDVLEERFLDINPYCRCRAIQVYMRLcdLDQKFPKRRQKAAELaARSLEDKSSNVRRNAIKLLARLVS 441
                 677888999*********************999999***9997666615799************99987765 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.44
        Cnd1  33 edpyVRktaaivvakL..ilndmvkek 57 
                 +dp  + +a +++akL  ++ ++++++
  EEA19741.1 957 PDPNLQAQATLCMAKLmcVSSEYCEKN 983
                 5888999*********99999999876 PP

  == domain 3  score: 149.6 bits;  conditional E-value: 3.8e-47
        Cnd1    1 liRalairtlg..cirvpnlveylvepLrkrLkDedpyVRktaaivvakLilndmvkekgflselaklleDenprVvanalaalteiseksenaiyn 95  
                  ++R++a+++lg  ++++++l++++++ L++rL+D+d+ V++t++++++ Lil++ vk+kg+l e+ak+leD+++r+ ++a++++te+++k+ na+yn
  EEA19741.1  998 IVRSNAVIALGdmAVCFNHLIDENTDFLYRRLNDSDASVKRTCLMTLTFLILAGQVKVKGQLGEMAKCLEDDDKRIADLARMFFTELATKD-NAVYN 1093
                  69*****************************************************************************************.***** PP

        Cnd1   96 llpdiisklsdalnecsewgqitilefLlsyipkdkqeaeslveklcprlqhansavvlaaikviLs 162 
                   + di+s ls +  +++e + + i++fL+ +++k+k+ a++l++kl++rl+ ++++++++++++ Ls
  EEA19741.1 1094 HFVDIFSLLS-SERNLEESSLRRIIKFLAGFVEKEKH-AKQLADKLAARLTRCETERQWNDVAYALS 1158
                  **********.6799**********************.*************************9985 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0      0.11   2.1e+02       3      40 ..     329     377 ..     327     405 .. 0.60
   2 !   13.8   0.3   2.8e-05     0.057       8      54 ..     420     467 ..     413     475 .. 0.89
   3 ?   -1.7   0.0         2     4e+03      59      81 ..     693     715 ..     646     719 .. 0.74
   4 ?   -2.6   0.0       3.8   7.6e+03      18      37 ..     771     796 ..     760     805 .. 0.41
   5 !   24.3   0.0   1.6e-08   3.1e-05       1      55 [.     984    1044 ..     955    1077 .. 0.54

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.11
      HEAT_2   3 aLlqalendpdpevrraairaLg....rignp...........ealpaLvell 40 
                 +L ++l +++++ +r a+i++ g    +               + ++a++++l
  EEA19741.1 329 LLAKQL-DSESYTLRCAIIEVCGnliaD---LskeeerdgsskSQINAFFDVL 377
                 578899.999999999999999964441...2222334444433344444444 PP

  == domain 2  score: 13.8 bits;  conditional E-value: 2.8e-05
      HEAT_2   8 lendpdpevrraairaLgrignpealpaLve.llededpavRraaaea 54 
                   +d++ +vrr+ai+ L+r+ ++  +  ++   l ++d+a R +a+ea
  EEA19741.1 420 SLEDKSSNVRRNAIKLLARLVSTHPFSVMHGgQLAHKDWAARLEAVEA 467
                 4489**************************9788************97 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 2
      HEAT_2  59 gdpealpaLkellddddddvvRe 81 
                 ++  ++ +L +l++ ++d vvRe
  EEA19741.1 693 QRRGSIIVLGMLALAEPDIVVRE 715
                 45668888999999999999997 PP

  == domain 4  score: -2.6 bits;  conditional E-value: 3.8
      HEAT_2  18 raairaLg.....rig.npealpaLv 37 
                  aai ++      ++g  ++a+ a+ 
  EEA19741.1 771 LAAITEISsdskeWYGvAEQAISAIY 796
                 34444433322221211123333333 PP

  == domain 5  score: 24.3 bits;  conditional E-value: 1.6e-08
      HEAT_2    1 ldaLlqalendpdpevrraairaLg......rignpealpaLvellededpavRraaaeaL 55  
                  l++L+ ++e+++dp vr +a++aLg      +   +e  + L + l+d+d+ v r+  ++L
  EEA19741.1  984 LPLLITIMERSEDPIVRSNAVIALGdmavcfNHLIDENTDFLYRRLNDSDASVKRTCLMTL 1044
                  3556666666666666666666666333322222235566666666666666666666666 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.1     0.028        55       3      28 ..     328     353 ..     327     356 .. 0.90
   2 !   12.4   0.0   7.3e-05      0.14       7      30 ..     419     442 ..     405     443 .. 0.91
   3 ?   -2.7   0.1       5.3   1.1e+04       9      23 ..     453     467 ..     452     467 .. 0.86
   4 ?   -0.8   0.0       1.3   2.7e+03      11      30 ..     781     801 ..     772     801 .. 0.79
   5 !   13.7   0.0   2.9e-05     0.058       2      28 ..     984    1011 ..     984    1014 .. 0.93
   6 !    6.3   0.0     0.007        14       4      25 ..    1024    1045 ..    1023    1048 .. 0.88

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.028
                 HHHHHHHT-SSHHHHHHHHHHHHHHH CS
        HEAT   3 PlllkllsDpspeVReaAakaLgala 28 
                  ll k l ++s   R+a ++ +g+l+
  EEA19741.1 328 TLLAKQLDSESYTLRCAIIEVCGNLI 353
                 68999******************997 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 7.3e-05
                 HHHT-SSHHHHHHHHHHHHHHHHC CS
        HEAT   7 kllsDpspeVReaAakaLgalaev 30 
                 + l+D+s++VR++A+k L++l++ 
  EEA19741.1 419 RSLEDKSSNVRRNAIKLLARLVST 442
                 579******************985 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 5.3
                 HT-SSHHHHHHHHHH CS
        HEAT   9 lsDpspeVReaAaka 23 
                 l ++++  R  A++a
  EEA19741.1 453 LAHKDWAARLEAVEA 467
                 6799******99986 PP

  == domain 4  score: -0.8 bits;  conditional E-value: 1.3
                 -SSHH.HHHHHHHHHHHHHHC CS
        HEAT  11 Dpspe.VReaAakaLgalaev 30 
                 ++++  V e A+ a+ al+++
  EEA19741.1 781 SKEWYgVAEQAISAIYALSKH 801
                 3777779999*******9986 PP

  == domain 5  score: 13.7 bits;  conditional E-value: 2.9e-05
                  HHHHHHHH.T-SSHHHHHHHHHHHHHHH CS
        HEAT    2 lPlllkll.sDpspeVReaAakaLgala 28  
                  lPll++ + ++++p VR++A+ aLg++a
  EEA19741.1  984 LPLLITIMeRSEDPIVRSNAVIALGDMA 1011
                  799999999*****************98 PP

  == domain 6  score: 6.3 bits;  conditional E-value: 0.007
                  HHHHHHT-SSHHHHHHHHHHHH CS
        HEAT    4 lllkllsDpspeVReaAakaLg 25  
                  +l + l+D++++V ++++ +L+
  EEA19741.1 1024 FLYRRLNDSDASVKRTCLMTLT 1045
                  67889*************9996 PP

>> Adaptin_N  Adaptin N terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.7   0.1   0.00027      0.54     192     303 ..     329     448 ..     277     454 .. 0.67
   2 ?    0.8   0.0     0.067   1.3e+02     155     196 ..     772     816 ..     758     831 .. 0.78
   3 !   10.3   0.1   9.1e-05      0.18     126     177 ..     957    1008 ..     952    1020 .. 0.92

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00027
                 HHHCCHHHHHHCS-HHHHHHHHHHHCC---SSHHHH..........HHHHHHHCGGCGCSSCHHHHHHHHHCCHCCCCST....HHHCCHHCHHHHHHS CS
   Adaptin_N 192 klvrrLcnllteldpwlqvkiiklltrlarqepeersk........kellesllnllqssnnaVlletvnlivelapkne....livlavnaLvrllss 278
                 +l+++L+    + +  l + ii++  +l++   +e+++        + +++ l++++   n++    +++++++l + ++     +++a++   r l++
  EEA19741.1 329 LLAKQLD----SESYTLRCAIIEVCGNLIADLSKEEERdgssksqiNAFFDVLEERFLDINPYCRCRAIQVYMRLCDLDQkfpkRRQKAAELAARSLED 423
                 4444433....3344466777777666666544444334455677777788888888888888888888888855555555557778888888888888 PP

                 SCCTCHHHHHCHHHHHHHHXXTTTT CS
   Adaptin_N 279 kdenlryvaLrtllkivkkepkavq 303
                 k  n+r  a++ l+++v+++p +v 
  EEA19741.1 424 KSSNVRRNAIKLLARLVSTHPFSVM 448
                 8888888888888888888876665 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.067
                 HHHHHCTT-SS..HHHHHHHHHHHHHHHCCCCCCC.HHHHHHHCC CS
   Adaptin_N 155 eeikellsdkd..pgvvlaAvalleeikkndrlll.kllpklvrr 196
                   i+e+ sd++  +gv   A+++++ + k+++ l+ ++++  +r 
  EEA19741.1 772 AAITEISSDSKewYGVAEQAISAIYALSKHPDVLCsDIIRRKTRE 816
                 56777777777799*************888888787998877665 PP

  == domain 3  score: 10.3 bits;  conditional E-value: 9.1e-05
                  SSHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHCT.T-SSHHHHHHHHHHHH CS
   Adaptin_N  126 rspyvrkkAalailklykkdpdllrkqlveeikell.sdkdpgvvlaAvalle 177 
                  ++p ++ +A l+++kl+ ++++ ++k+ ++ ++ ++  ++dp+v ++Av +l 
  EEA19741.1  957 PDPNLQAQATLCMAKLMCVSSEYCEKN-LPLLITIMeRSEDPIVRSNAVIALG 1008
                  789999********************9.********88999********9985 PP

>> RTP1_C1  Required for nuclear transport of RNA pol II C-terminus 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   0.0    0.0001      0.21      10      76 ..     383     448 ..     327     453 .. 0.91
   2 ?   -2.7   0.0       3.2   6.5e+03      13      70 ..     959    1013 ..     955    1018 .. 0.59
   3 !    7.8   0.0    0.0018       3.6       6      71 ..    1027    1106 ..    1024    1144 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.0001
     RTP1_C1  10 dpllpvrahglvlLrkliekkskeavldiekilkllleaLkdedsYvYLnaikgLvaLadvfpeevl 76 
                 d  + +r ++++   +l+   + +  +  +k ++l  ++L+d+ s v  naik+L+ L++++p +v+
  EEA19741.1 383 DINPYCRCRAIQVYMRLCDLDQ-KFPKRRQKAAELAARSLEDKSSNVRRNAIKLLARLVSTHPFSVM 448
                 5567788888888888887776.67889999*******************************98887 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 3.2
     RTP1_C1   13 lpvrahglvlLrkliekkskeavldiekilkllleaLkdedsYvYLnaikgLvaLadv 70  
                  + ++a++ + ++kl+  +s+  +++++ +++++ +    ed+ v  na+ +L  +a  
  EEA19741.1  959 PNLQAQATLCMAKLMCVSSEYCEKNLPLLITIMER---SEDPIVRSNAVIALGDMAVC 1013
                  66677777777777777664444444444444432...56666777777777776655 PP

  == domain 3  score: 7.8 bits;  conditional E-value: 0.0018
     RTP1_C1    6 kdlqdpllpvrahglvlLrkliekkske..............avldiekilkllleaLkdedsYvYLnaikgLvaLadvf 71  
                  + l+d+ + v+  +l++L+ li + + +              + + i  +++++++ L+ +d  vY + + +++ L +  
  EEA19741.1 1027 RRLNDSDASVKRTCLMTLTFLILAGQVKvkgqlgemakcledDDKRIADLARMFFTELATKDNAVYNHFVDIFSLLSSER 1106
                  6799********************998899***********99999**********************999999988754 PP

>> Cnd3  Nuclear condensing complex subunits, C-term domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.1      0.41   8.2e+02     142     142 ..     347     347 ..     208     446 .. 0.59
   2 ?   -0.9   0.0      0.38   7.6e+02      48     101 ..     394     450 ..     372     468 .. 0.67
   3 !   18.6   0.8   4.2e-07   0.00084      39     174 ..     958    1089 ..     944    1149 .. 0.82

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.41
                 H CS
        Cnd3 142 e 142
                 e
  EEA19741.1 347 E 347
                 2 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.38
                 HHHHHHHTT-H...HHHHHHHHHHHHHHHHS-HHHHHHHHHHHHHHHHHH-CGGGGG CS
        Cnd3  48 kcLglfclldk...klakenlklflqalskgneelkiialkaifDllllhglevldk 101
                      +c ld+   k  +++ +l  ++l+ + ++++  a+k +  l+++h+++v+  
  EEA19741.1 394 QVYMRLCDLDQkfpKRRQKAAELAARSLEDKSSNVRRNAIKLLARLVSTHPFSVMHG 450
                 555555555553333344555566666666677888888888888888888887755 PP

  == domain 3  score: 18.6 bits;  conditional E-value: 4.2e-07
                  SHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHS.-HHHHHHHHHHHHHHHHHH-CGGGGGGHH..............HHHHHHHHHHC-TT-H CS
        Cnd3   39 eaairelglkcLglfclldkklakenlklflqalskg.neelkiialkaifDllllhglevldkekkedsdeeeeesessksllkllykaLdsednp 134 
                  +++++ ++  c++ +++++ +++++nl+l++++++++ ++ ++  a+ a+ D++  +   ++d+                   +++ly+ L+++ ++
  EEA19741.1  958 DPNLQAQATLCMAKLMCVSSEYCEKNLPLLITIMERSeDPIVRSNAVIALGDMAVCFNH-LIDE------------------NTDFLYRRLNDS-DA 1034
                  8999*******************************887999****************98.5543..................357888888654.58 PP

                  HHHHHHHHHHHHHHHHH--..............SHHHHHHHHHHHHH-GG.GTT- CS
        Cnd3  135 elqaiaaeglcKLllagil..............tdselLsrLvllyFnpe.teen 174 
                  +++ +    l  L+lag +              +d++ ++ L  ++F +  t++n
  EEA19741.1 1035 SVKRTCLMTLTFLILAGQVkvkgqlgemakcleDDDKRIADLARMFFTELaTKDN 1089
                  8888888888888888888777777777777755556888888888877755554 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0         3   5.9e+03      28      55 .]     325     352 ..     314     352 .. 0.67
   2 ?    3.9   0.2      0.04        80      35      55 .]     419     439 ..     414     439 .. 0.86
   3 ?   -0.5   0.2      0.92   1.8e+03      30      55 .]     724     745 ..     692     745 .. 0.55
   4 !   11.6   0.0   0.00016      0.32       3      54 ..     961    1009 ..     959    1010 .. 0.72
   5 !    6.3   0.0     0.007        14      25      53 ..    1017    1045 ..    1014    1047 .. 0.86
   6 ?   -2.6   0.0       4.2   8.4e+03      32      45 ..    1061    1074 ..    1057    1077 .. 0.76

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 3
     HEAT_EZ  28 eilpaLlalLnddsdeVRaaAagaLgnl 55 
                 + + +L++ L ++s + R+a +  +gnl
  EEA19741.1 325 KQMTLLAKQLDSESYTLRCAIIEVCGNL 352
                 5577778888555447799988888876 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.04
     HEAT_EZ  35 alLnddsdeVRaaAagaLgnl 55 
                 + L+d+s++VR +A+  L++l
  EEA19741.1 419 RSLEDKSSNVRRNAIKLLARL 439
                 5789************99986 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 0.92
     HEAT_EZ  30 lpaLlalLnddsdeV.RaaAagaLgnl 55 
                 l +L+      sd+V   +++ aL+++
  EEA19741.1 724 LGELG-----RSDLVlARYTCVALRRM 745
                 45566.....88888888888888876 PP

  == domain 4  score: 11.6 bits;  conditional E-value: 0.00016
     HEAT_EZ    3 vRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLgn 54  
                  +++ A +++    +  ++  + + ++ lp+L+  ++ ++d  VR +A++aLg 
  EEA19741.1  961 LQAQATLCM----AKLMCVSSEYCEKNLPLLITIMERSEDpIVRSNAVIALGD 1009
                  566666666....34455677788899********55555388********95 PP

  == domain 5  score: 6.3 bits;  conditional E-value: 0.007
     HEAT_EZ   25 lvpeilpaLlalLnddsdeVRaaAagaLg 53  
                  l++e  ++L ++Lnd++++V+ +++ +L+
  EEA19741.1 1017 LIDENTDFLYRRLNDSDASVKRTCLMTLT 1045
                  5677788999**************99997 PP

  == domain 6  score: -2.6 bits;  conditional E-value: 4.2
     HEAT_EZ   32 aLlalLnddsdeVR 45  
                  +++++L+dd++++ 
  EEA19741.1 1061 EMAKCLEDDDKRIA 1074
                  57899999999875 PP

>> Cohesin_HEAT  HEAT repeat associated with sister chromatid cohesion
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0       3.1   6.1e+03       8      23 ..      59      74 ..      58      75 .. 0.86
   2 ?   -3.1   0.0       5.1     1e+04      19      29 ..     373     383 ..     367     385 .. 0.89
   3 ?    1.9   0.1      0.14   2.8e+02      25      42 .]     419     436 ..     418     436 .. 0.90
   4 ?   -3.1   0.0       5.1     1e+04       8      20 ..     799     811 ..     798     812 .. 0.84
   5 ?    7.0   0.0    0.0036       7.1      25      39 ..    1027    1041 ..    1013    1044 .. 0.88

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 3.1
                  HH-GGGGGSHHHHHHH CS
  Cohesin_HEAT  8 ekdpsiLsapevldti 23
                   ++p +L +p++ d++
    EEA19741.1 59 AANPEMLMRPSFFDSL 74
                  689*********9987 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 5.1
                   HHHHHHHHHHS CS
  Cohesin_HEAT  19 vldtiarrltD 29 
                   + d++++r++D
    EEA19741.1 373 FFDVLEERFLD 383
                   8899*****99 PP

  == domain 3  score: 1.9 bits;  conditional E-value: 0.14
                   HHHHSS-HHHHHHHHHHH CS
  Cohesin_HEAT  25 rrltDsspsVRdAaLell 42 
                   r l+D s+ VR  a++ll
    EEA19741.1 419 RSLEDKSSNVRRNAIKLL 436
                   789*********999997 PP

  == domain 4  score: -3.1 bits;  conditional E-value: 5.1
                   HH-GGGGGSHHHH CS
  Cohesin_HEAT   8 ekdpsiLsapevl 20 
                   +k+p++L +++++
    EEA19741.1 799 SKHPDVLCSDIIR 811
                   899****999886 PP

  == domain 5  score: 7.0 bits;  conditional E-value: 0.0036
                    HHHHSS-HHHHHHHH CS
  Cohesin_HEAT   25 rrltDsspsVRdAaL 39  
                    rrl+Ds++sV+ ++L
    EEA19741.1 1027 RRLNDSDASVKRTCL 1041
                    8**********9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1182 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       927  (0.0517039); expected 358.6 (0.02)
Passed bias filter:                      554  (0.0308997); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.91u 0.34s 00:00:01.25 Elapsed: 00:00:00.50
# Mc/sec: 7173.05
//
Query:       EEA19742.1  [L=516]
Description: cell cycle protein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      3e-42  144.8   0.0    1.9e-39  135.6   0.0    2.9  2  Pkinase         Protein kinase domain
    5.6e-10   38.9   0.0    8.5e-06   25.2   0.0    3.1  3  Pkinase_Tyr     Protein tyrosine kinase
      0.002   18.1   0.1       0.45   10.4   0.0    2.6  3  APH             Phosphotransferase enzyme family
  ------ inclusion threshold ------
      0.013   14.3   0.0      0.034   12.9   0.0    1.6  2  Pkinase_fungal  Fungal protein kinase
        6.9    6.5  10.5       0.33   10.8   4.3    1.8  2  Sigma70_ner     Sigma-70, non-essential region


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.1   0.0    0.0034        12       2      19 ..     105     122 ..     104     128 .. 0.85
   2 !  135.6   0.0   5.4e-43   1.9e-39      18     264 .]     166     476 ..     162     476 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0034
                 EEEEEEEEESSEEEEEEE CS
     Pkinase   2 ekleklGeGsfGkVykav 19 
                 + ++++GeG+f++Vyka 
  EEA19742.1 105 RLINRIGEGTFSTVYKAE 122
                 56789***********96 PP

  == domain 2  score: 135.6 bits;  conditional E-value: 5.4e-43
                 EEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHS.CTTB--EEEEEEESSEEEEEEE--TTEBHHHHHHHHSS--HHHHHHHHHHHHHHHHHHH CS
     Pkinase  18 aveketgkivAvKkikkekakkkkekkvlrEikilkklk.hpnivrlyevfeekdelylvleyveggeladllerkgslseeeakkiakqilegleylH 115
                 +++k++ + vA+Kki + +       ++++E+++l+ l+ +  ++ l+ +f+++d+++ vl y +++++   ++   ++  +++++++++++++l+++H
  EEA19742.1 166 GKKKKKPRYVALKKIYVTSSPL----RIQNELELLHDLRgSTSVCPLITAFRHQDQVVAVLPYFPHTDFRIQYR---TFMVRDMRHYFQSLFTALAFVH 257
                 67889999*******9997665....578************************************987766665...7********************* PP

                 HTTEE-SS-SGGGEEEE.TTTEEEE-SGTTSEESSSSCS.........................................BCTTTSCGGGS-HHHH.TT CS
     Pkinase 116 skgiiHrDlKpeNiLid.ekgelKitDFGlakelesssk.........................................ltsfvgtseYlAPEvl.ke 171
                 ++gi+HrD+Kp N+L++ e +   ++DFGla++  s+ +                                           ++ gt+ ++APEvl k 
  EEA19742.1 258 KHGILHRDIKPTNFLYNpELRRGVLVDFGLAERQGSDYTgpclctnpaqvrqmrlqssyytnqpahqqngypkndprparRANRAGTRGFRAPEVLfKC 356
                 *****************7777799*************99****************************************999**************999 PP

                 SCBSHHHHHHHHHHHHHHHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCT..SHH...HHHTTS...............................-HHH CS
     Pkinase 172 neyskkvDvWslGvilyelltgkppfsgekgkekvekeldqlekilkilg..etkeklpeasei...............................seea 237
                 ++ ++k+D+Ws+Gvil++ll ++ pf ++ ++       + l +++ i+g   +k +   + +i                               +++ 
  EEA19742.1 357 TSQTTKIDMWSAGVILLTLLGRRFPFFNSADDV------EALIEMASIFGvrRMKYAASLHGQIfetniptigekgygweklviwsscvedltesEQQG 449
                 999************************555544......333334444443233334444444466778888999*******************9999* PP

                 HHHHHHHT-SSGCCSTTHHHHHTSGGG CS
     Pkinase 238 kdllkkllkkdpkkRltaeellqhpyl 264
                 ++ll+ l++ +p+kRl+a+e+lqh+++
  EEA19742.1 450 IRLLSGLMELNPNKRLSAKEALQHEFF 476
                 *************************98 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0     0.025        88       2      19 ..     105     122 ..     104     134 .. 0.85
   2 !   25.2   0.0   2.4e-09   8.5e-06      22     153 ..     166     291 ..     155     307 .. 0.85
   3 !    7.6   0.0   0.00057         2     170     198 ..     346     375 ..     329     397 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.025
                  EEEEEEEEESSEEEEEEE CS
  Pkinase_Tyr   2 elgkklGeGafGkVvegt 19 
                  +l +++GeG+f++V++++
   EEA19742.1 105 RLINRIGEGTFSTVYKAE 122
                  57889**********996 PP

  == domain 2  score: 25.2 bits;  conditional E-value: 2.4e-09
                  TTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS.-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHTCTTTSBHHHHHHHHHHHHHHHHH CS
  Pkinase_Tyr  22 gekekkevkVavKtlkeeateeekeelleeakimkkl.khpnivkllgvctkeepllivteyvkgGdLlkfLrkkekekltlkdllsfalqvAkGmey 118
                  g+k+kk   Va+K++      ++  ++ +e++++++l     +  l+ +  ++++++ v+ y ++ d++        +++ ++d+ ++ + +  ++++
   EEA19742.1 166 GKKKKKPRYVALKKIYV---TSSPLRIQNELELLHDLrGSTSVCPLITAFRHQDQVVAVLPYFPHTDFRIQY-----RTFMVRDMRHYFQSLFTALAF 255
                  378888999***99933...334679***********88999***********************9987544.....46799**************** PP

                  HHHTTEEEST-SGGGEEEEETT.EEEE-STTTHEET CS
  Pkinase_Tyr 119 LeskklvHrdlaarNvLlsenk.vvkisDfGLardi 153
                  ++++ ++Hrd+   N L + +     + DfGLa++ 
   EEA19742.1 256 VHKHGILHRDIKPTNFLYNPELrRGVLVDFGLAERQ 291
                  ******************9765266789*****976 PP

  == domain 3  score: 7.6 bits;  conditional E-value: 0.00057
                  GGS-HHHHHHSE.EEHHHHHHHHHHHHHHH CS
  Pkinase_Tyr 170 kWmapEslkekk.ftsksDvWsfGvllwEi 198
                   + apE+l++++  t+k D+Ws Gv+l  +
   EEA19742.1 346 GFRAPEVLFKCTsQTTKIDMWSAGVILLTL 375
                  578*****99986899*********99755 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.3   0.1    0.0044        16      26      85 ..     179     236 ..     165     259 .. 0.73
   2 !   10.4   0.0   0.00013      0.45     165     196 ..     258     288 ..     241     291 .. 0.82
   3 ?   -3.5   0.0       2.2   7.7e+03      49      66 ..     344     361 ..     336     367 .. 0.77

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0044
                 EEE-TTS-HHHHHHHHHHHHHHHHTT-B--B-CTTBS-EEETTEEEEEEE----EE-SS...H CS
         APH  26 rrnpparaaeeirrevallrlLakagvpvPevlagdtddeeigllfalieyvpgrsllr...k 85 
                 +++ ++ ++ +i++e++ll+ L+++   +P + a+     ++  ++a+++y p ++++    +
  EEA19742.1 179 KIYVTS-SPLRIQNELELLHDLRGSTSVCPLITAF----RHQDQVVAVLPYFPHTDFRIqyrT 236
                 455556.8999************998889999995....788889999999999998875554 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00013
                 -EEEE-SS-SGGGEEEC..TTEEEEE---TT- CS
         APH 165 ptvllHgDlhpgNllvdpddgrvtGviDfeda 196
                 ++++lH+D++p N+l +p+  r   ++Df++a
  EEA19742.1 258 KHGILHRDIKPTNFLYNPELRRG-VLVDFGLA 288
                 689**************665553.599**988 PP

  == domain 3  score: -3.5 bits;  conditional E-value: 2.2
                 HTT-B--B-CTTBS-EEE CS
         APH  49 kagvpvPevlagdtddee 66 
                  +g+++Pevl  +t+++ 
  EEA19742.1 344 TRGFRAPEVLFKCTSQTT 361
                 567799****99999875 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.1      0.33   1.2e+03     213     247 ..      47      81 ..      40     179 .. 0.72
   2 ?   12.9   0.0   9.6e-06     0.034     324     386 ..     257     353 ..     239     369 .. 0.74

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.33
  Pkinase_fungal 213 ekdddiaeiRkgldvtka.ekfrskrkvvsssssqe 247
                     e++d+ ++iR++ +  ++ +k ++ ++  ++  +++
      EEA19742.1  47 EAKDTKHHIRDDANEDNDeKKYDK-DEHYEDEDEEP 81 
                     566777888888888888444444.44344333333 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 9.6e-06
  Pkinase_fungal 324 lkagiLHrDiSenNilitdskkegerkglLiDLDlakelsddssesgare........................................rtGTl 378
                     +k giLHrDi   N l +     + r+g+L+D+ la   + d +    +                                         r GT+
      EEA19742.1 257 HKHGILHRDIKPTNFLYN----PELRRGVLVDFGLAERQGSDYTGP--CLctnpaqvrqmrlqssyytnqpahqqngypkndprparranRAGTR 345
                     499************999....679***********9988544433..22234555566666666677777777777777777777777777777 PP

  Pkinase_fungal 379 eFmaievl 386
                      F a evl
      EEA19742.1 346 GFRAPEVL 353
                     77777776 PP

>> Sigma70_ner  Sigma-70, non-essential region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   4.3   9.3e-05      0.33      34      89 ..      48     102 ..      28     141 .. 0.73
   2 ?   -1.8   0.4      0.65   2.3e+03      35      51 ..     492     508 ..     453     514 .. 0.60

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 9.3e-05
  Sigma70_ner  34 eeeeeeeeeedeeeeeeeeddd..eeeseseaadeeelkeealekfeelreqyeklrk 89 
                  +++++    +d++e+++e   +  +++++ e++dee+  + ++e +++l++++  ++k
   EEA19742.1  48 AKDTKHHIRDDANEDNDE---KkyDKDEHYEDEDEEPVDPSVREDMKRLEDTFTGISK 102
                  333333332332222222...13568899***********************998887 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.65
  Sigma70_ner  35 eeeeeeeeedeeeeeee 51 
                  +eee e++++++ +e++
   EEA19742.1 492 DEEEGESTAEQQPQEDA 508
                  22332222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (516 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       802  (0.044732); expected 358.6 (0.02)
Passed bias filter:                      504  (0.0281109); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.63u 0.31s 00:00:00.94 Elapsed: 00:00:00.51
# Mc/sec: 3071.66
//
Query:       EEA19743.1  [L=242]
Description: protein-L-isoaspartate O-methyltransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-61  208.3   0.0    4.1e-61  206.4   0.0    1.7  1  PCMT             Protein-L-isoaspartate(D-aspartate) O-methyl
    1.2e-05   25.2   0.0    1.7e-05   24.7   0.0    1.3  1  Methyltransf_31  Methyltransferase domain
    8.9e-05   23.1   0.0    0.00038   21.1   0.0    1.9  2  Methyltransf_25  Methyltransferase domain
    0.00026   20.8   0.0    0.00044   20.1   0.0    1.2  1  Methyltransf_23  Methyltransferase domain
    0.00036   20.5   0.0     0.0006   19.8   0.0    1.3  1  Methyltransf_32  Methyltransferase domain
     0.0074   15.9   0.0      0.013   15.1   0.0    1.3  1  MetW             Methionine biosynthesis protein MetW
  ------ inclusion threshold ------
      0.017   15.9   0.0       0.06   14.1   0.0    1.9  2  Methyltransf_12  Methyltransferase domain
      0.062   14.0   0.0       0.23   12.1   0.0    1.9  2  Methyltransf_11  Methyltransferase domain
       0.14   11.8   0.0       0.19   11.4   0.0    1.2  1  GCD14            tRNA methyltransferase complex GCD14 subunit
       0.19   11.2   0.0       0.32   10.5   0.0    1.4  1  MTS              Methyltransferase small domain


Domain annotation for each model (and alignments):
>> PCMT  Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  206.4   0.0   2.3e-64   4.1e-61       2     208 ..       9     240 ..       8     242 .] 0.91

  Alignments for each domain:
  == domain 1  score: 206.4 bits;  conditional E-value: 2.3e-64
                 HHHHHHHHHHHTTS---HHHHHHHHHS-GGGGSSCGGGGGTTSSS-EEEETTEEE--HHHHHHHHHHTT..--TT-EEEEES-TTSHHHHHHHHHHCTT CS
        PCMT   2 kkealieelkkkgviksdkvaealeevdReefvpesfkekaYedaplsigynatiSaphmvalalelle..lkkgarvLevGsGsGyltavlarlvgek 98 
                 ++ +lie+l   g+ik+++v +a++ vdR++++p+    ++Y d+p++igy+atiSaphm+a a+e+l   l++g+rvL++GsGsGylt v+a+l+ + 
  EEA19743.1   9 TNTELIENLWGAGLIKDKRVKKAMLGVDRDHYAPS----SPYSDSPQPIGYGATISAPHMHAHACEYLIdfLRPGSRVLDIGSGSGYLTHVIANLITDP 103
                 5789*******************************....9****************************999************************9875 PP

                 C........EEEEEESBHHHHHHHHHHHHHCTTC.......SEEEEES-GGGTTGGG-SEEEEEESSBBSS--HHHHHTEEEEEEEEEEESB.SSS... CS
        PCMT  99 g........rvvsierikelveeakrnlkkldle.......nvivvvgDGrkGyeekaPYdaihvgaaapeiPealidQLkeGGrlvvPvge.eee... 178
                          +v++ie+i+elv+ ++ n++k++         +v++ + DGrkG+++  PYdaihvgaaa e+  +l+dQL+  Gr+ +Pv++ ++e   
  EEA19743.1 104 SspptdadgHVIGIEHIQELVDLSRDNMNKSEDGrnflssgKVQFLCEDGRKGWPQGGPYDAIHVGAAAVELHATLVDQLQAPGRMFIPVESeSREggl 202
                 556666666********************9987778999***************************************************975222333 PP

                 ........EEEEEEEEETTTEEEEEEEEEE---B-BCC CS
        PCMT 179 ........Qvlklvdkkadgkvvikkleevrfvpltdk 208
                         Q++ +vdkkadg+vv +k+ +v +vpltd 
  EEA19743.1 203 rqvgmgtgQYIWVVDKKADGTVVKEKVFAVSYVPLTDA 240
                 3344444499**************************85 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.0   9.5e-09   1.7e-05       3      51 ..      78     134 ..      76     167 .. 0.85

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 9.5e-09
  Methyltransf_31   3 kglrvlDlGCGtGeltfelae.....elgp.....kaevvGiDiseeaielArenaqkl 51 
                       g rvlD+G+G+G+lt+++a         +     +++v+Gi+  +e + l+r n  k 
       EEA19743.1  78 PGSRVLDIGSGSGYLTHVIANlitdpS--SpptdaDGHVIGIEHIQELVDLSRDNMNKS 134
                      5789****************8666552..033555788***************987764 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.1   0.0   2.1e-07   0.00038       1      71 [.      82     169 ..      82     187 .. 0.80
   2 ?   -1.1   0.0       1.8   3.3e+03       4      19 ..     205     220 ..     204     233 .. 0.74

  Alignments for each domain:
  == domain 1  score: 21.1 bits;  conditional E-value: 2.1e-07
                      EEEET-TTSHHHHHHHCTS......T...SSEEEEEESSHHHHHHHHHHHHH....TTT....TEEEEESBCCGBSSSTTTEEEEEEE CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrl......g...kakvtgvDiseemleaareraee....egl....nvefvqgdaedlpfedgsfDlvvss 71 
                      vLd+G G+G lt  +a+ +      +   +++v+g++  +e+++  r ++++    +++    +v+f++ d ++   + g +D++++ 
       EEA19743.1  82 VLDIGSGSGYLTHVIANLItdpsspPtdaDGHVIGIEHIQELVDLSRDNMNKsedgRNFlssgKVQFLCEDGRKGWPQGGPYDAIHVG 169
                      9***************99666555414569*****************9999866553337888*********99777889****9983 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 1.8
                      ET-TTSHHHHHHHCTS CS
  Methyltransf_25   4 lGcGtGrltlalakrl 19 
                      +G GtG+++  + k+ 
       EEA19743.1 205 VGMGTGQYIWVVDKKA 220
                      899***9887777664 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   0.0   2.4e-07   0.00044      14      87 ..      70     167 ..      62     170 .. 0.81

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 2.4e-07
  Methyltransf_23  14 erllpklraggrvLdiGcGtGillevlre................ngf.svt.gvDlspeaveiae......kakkaqkdqfdeqeaaepqgkf 83 
                      e l + lr+g+rvLdiG G+G+l+ v++                  g  ++  +vDls+ + ++ e      +  k q+ ++d  + +++ g +
       EEA19743.1  70 EYLIDFLRPGSRVLDIGSGSGYLTHVIANlitdpsspptdadghvIGIeHIQeLVDLSRDNMNKSEdgrnflSSGKVQFLCEDGRKGWPQGGPY 163
                      566667899******************887888888887776665444433348888888888877***99999999999999999999***** PP

  Methyltransf_23  84 dlIv 87 
                      d I+
       EEA19743.1 164 DAIH 167
                      *998 PP

>> Methyltransf_32  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.0   3.4e-07    0.0006      26      74 ..      79     134 ..      64     147 .. 0.80

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 3.4e-07
  Methyltransf_32  26 altvvDvGaGkgYLsfvlal.....kek...eyklkvvgidakeelvekaekraekl 74 
                        +v+D+G+G gYL+ v+a      + +   +   +v+gi+  +elv+ +++  +k 
       EEA19743.1  79 GSRVLDIGSGSGYLTHVIANlitdpS-SpptDADGHVIGIEHIQELVDLSRDNMNKS 134
                      5689***************9997652.1454699************99888777665 PP

>> MetW  Methionine biosynthesis protein MetW
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   7.3e-06     0.013       5      33 ..      70      98 ..      67     104 .. 0.88

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 7.3e-06
        MetW  5 eliaelikpgsrvldlGcGdGellellke 33
                e++ ++++pgsrvld+G+G G l +++++
  EEA19743.1 70 EYLIDFLRPGSRVLDIGSGSGYLTHVIAN 98
                5678899****************998765 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   3.3e-05      0.06       1      72 [.      83     168 ..      83     185 .. 0.58
   2 ?   -1.3   0.0       2.1   3.8e+03       3      17 ..     205     219 ..     204     226 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 3.3e-05
  Methyltransf_12   1 LeiGcGtGsllrallekl.........pdieytgvDispsaiedakeklakre....nnnnnnvelealdlldldgg......ssfDlvva 72 
                      L+iG+G+G l++++++ +          d +++g++  ++ ++  +  ++k e     ++  +v++  +d      +      + +D++++
       EEA19743.1  83 LDIGSGSGYLTHVIANLItdpsspptdADGHVIGIEHIQELVDLSRDNMNKSEdgrnFLSSGKVQFLCEDG-----RkgwpqgGPYDAIHV 168
                      8****************977777777744444444444444433333333333000033333333333333.....134555888888875 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 2.1
  Methyltransf_12   3 iGcGtGsllrallek 17 
                      +G GtG+++ ++ +k
       EEA19743.1 205 VGMGTGQYIWVVDKK 219
                      899*****9999887 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   0.00013      0.23       1      54 [.      83     155 ..      83     184 .. 0.80
   2 ?   -1.4   0.0       2.1   3.8e+03       3      18 ..     205     220 ..     204     235 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00013
                      EEET-TTSHHHHHHH..........HTT..SEEEEEES-HHHHHHHHHHCCHHT-........EEEETTEECCC CS
  Methyltransf_11   1 LdvGcGtGrlaeala..........krg..arvvgvDlskemlklakekaseegl........kvefvvadaek 54 
                      Ld+G+G+G+l+  +a               ++v+g++  +e+++l++++ ++++         kv+f+++d +k
       EEA19743.1  83 LDIGSGSGYLTHVIAnlitdpssppT-DadGHVIGIEHIQELVDLSRDNMNKSEDgrnflssgKVQFLCEDGRK 155
                      8**************88877666552.1579************9998888888777889999999999999987 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 2.1
                      ET-TTSHHHHHHHHTT CS
  Methyltransf_11   3 vGcGtGrlaealakrg 18 
                      vG+GtG++   + k++
       EEA19743.1 205 VGMGTGQYIWVVDKKA 220
                      8999999987766554 PP

>> GCD14  tRNA methyltransferase complex GCD14 subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00011      0.19      38      87 ..      76     133 ..      69     159 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00011
       GCD14  38 lkpGsvvvesGtGsgslshaiartva.....Pt...Ghlftfefheqraekareefre 87 
                 l+pGs+v++ G Gsg l+h ia  ++     Pt   Gh+  +e+ ++ ++ +r+++++
  EEA19743.1  76 LRPGSRVLDIGSGSGYLTHVIANLITdpsspPTdadGHVIGIEHIQELVDLSRDNMNK 133
                 79*******************9987532222223337888888777777777777665 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00018      0.32      23      55 ..      72     102 ..      63     132 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00018
                 HHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC CS
         MTS  23 LletlpkelsgkvlDlGcGaGvlgaalakespe 55 
                 L++ l      +vlD+G+G G+l+ ++a+   +
  EEA19743.1  72 LIDFLRP--GSRVLDIGSGSGYLTHVIANLITD 102
                 6666665..668*************99987665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (242 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       351  (0.0195772); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 1679.85
//
Query:       EEA19744.1  [L=522]
Description: DnaJ and TPR domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.1e-21   76.7   0.5    3.9e-21   74.9   0.5    2.0  1  DnaJ        DnaJ domain
      2e-17   63.4   0.2    0.00015   22.2   0.3    4.1  3  TPR_19      Tetratricopeptide repeat
    3.3e-17   61.2   2.7     0.0018   18.2   0.0    7.2  7  TPR_2       Tetratricopeptide repeat
    4.2e-16   58.0   0.0    7.2e-06   25.6   0.0    6.1  6  TPR_1       Tetratricopeptide repeat
    1.1e-14   54.3   2.6    4.2e-05   23.6   0.3    4.8  4  TPR_9       Tetratricopeptide repeat
    1.1e-12   47.6   5.1      0.074   13.9   0.0    6.9  7  TPR_14      Tetratricopeptide repeat
    1.9e-12   46.3   2.6     0.0075   16.4   0.0    6.9  6  TPR_8       Tetratricopeptide repeat
      7e-09   35.1   0.6        0.6   10.3   0.0    5.3  5  TPR_7       Tetratricopeptide repeat
    6.2e-08   33.2   3.0     0.0012   19.5   0.0    5.2  5  TPR_16      Tetratricopeptide repeat
    1.5e-07   31.5   7.5     0.0098   16.1   1.4    4.8  6  ANAPC3      Anaphase-promoting complex, cyclosome, subunit 3
    1.6e-07   30.9   0.0      0.015   15.0   0.0    4.9  5  TPR_11      TPR repeat
    1.7e-07   31.4   9.8          2    9.2   0.0    8.2  8  TPR_6       Tetratricopeptide repeat
    1.4e-05   25.1   0.0      0.032   14.6   0.0    4.4  3  TPR_17      Tetratricopeptide repeat
    4.2e-05   23.7   5.6      0.066   13.5   0.0    4.9  4  TPR_12      Tetratricopeptide repeat
    0.00068   19.3   0.0     0.0052   16.4   0.0    2.4  4  HrpB1_HrpK  Bacterial type III secretion protein (HrpB1_HrpK)
  ------ inclusion threshold ------
      0.014   14.2   0.0       0.42    9.3   0.0    2.7  3  PknG_TPR    Protein kinase G tetratricopeptide repeat
      0.027   14.8   2.4        1.9    8.9   0.0    4.0  4  TPR_20      Tetratricopeptide repeat
      0.031   14.5   1.4      0.082   13.2   0.3    2.3  2  KORA        TrfB plasmid transcriptional repressor
      0.043   13.4   2.8      0.045   13.3   0.6    1.9  2  GCIP        Grap2 and cyclin-D-interacting
      0.063   13.4   3.9        2.5    8.2   0.0    4.1  5  Fis1_TPR_C  Fis1 C-terminal tetratricopeptide repeat
      0.086   11.5   0.0       0.13   10.9   0.0    1.2  1  Med15       ARC105 or Med15 subunit of Mediator complex non-f
       0.12   12.5   1.1         33    4.5   0.0    3.2  3  HAD_2       Haloacid dehalogenase-like hydrolase
       0.25   11.1   1.2          1    9.2   0.1    2.5  2  ClpS        ATP-dependent Clp protease adaptor protein ClpS
        7.5    6.9   5.9    1.1e+02    3.2   0.5    3.3  3  DsrD        Dissimilatory sulfite reductase D (DsrD)


Domain annotation for each model (and alignments):
>> DnaJ  DnaJ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.9   0.5   5.3e-24   3.9e-21       1      63 []     400     466 ..     400     466 .. 0.92

  Alignments for each domain:
  == domain 1  score: 74.9 bits;  conditional E-value: 5.3e-24
                 HHHHHHTSSTTG-HHHHHHHHHHHHHHHSTTTS....CCHHHHHHHHHHHHHHHHHHTSHHHHHHHH CS
        DnaJ   1 dyYeiLgvskdasedeIkkaYrklalkyHPDkn....pkdpeaeekFkeineAyevLsdpekRkqYD 63 
                 dyY+iLgvs+da++ +Ik+aYr+l + +HPDk      ++++ae k   ineAyevLsdpe R+++D
  EEA19744.1 400 DYYKILGVSRDADDRTIKRAYRQLTKIHHPDKAmsqgVSKEDAETKMASINEAYEVLSDPELRARFD 466
                 8******************************99554444459999********************99 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.0   1.3e-06   0.00096       2      62 ..      42     101 ..      41     109 .. 0.91
   2 !   16.6   0.0   1.1e-05    0.0085       2      58 ..     184     241 ..     183     250 .. 0.92
   3 !   22.2   0.3     2e-07   0.00015       9      67 ..     330     388 ..     326     390 .. 0.94

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 1.3e-06
      TPR_19   2 laegdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpddarya 62 
                 la g + +Ala++ +a + dp n     +    +l+lg+ ++A++  ++++e +pd  + a
  EEA19744.1  42 LATGSPRDALAYFDAAVARDPTNYLTIFQRGATYLSLGRDTQAIDDFNRVLELKPD-FDGA 101
                 68899**************************************************9.4444 PP

  == domain 2  score: 16.6 bits;  conditional E-value: 1.1e-05
      TPR_19   2 laegdyaeAlalleqalqedpknaearllL.AeallalgqldeAealLdalpeedpdd 58 
                 ++ gd +eAl  l+ +lq +p++ e  l+    + ++lg+++ A+a + + + +dpd+
  EEA19744.1 184 FEKGDIQEALGDLAHILQISPGSVEPHLQIsSTLFYSLGDYERAIAQIRKCLHSDPDS 241
                 578*************************998999999******************996 PP

  == domain 3  score: 22.2 bits;  conditional E-value: 2e-07
      TPR_19   9 eAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpddaryasLlAk 67 
                  A  + + +lq +p+++  +l+ A+ ++   +++ A+++L ++ e+ + + +++ Ll+k
  EEA19744.1 330 KAKTYCADILQLKPHSLHGLLYQAQTYIDEDEFERAINTLTTAKEHHQSSREVQELLQK 388
                 577888999************99*********************************987 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.1   0.0   0.00023      0.17       8      34 .]      38      64 ..      32      64 .. 0.92
   2 !   18.2   0.0   2.4e-06    0.0018       5      33 ..      69      97 ..      66      98 .. 0.94
   3 ?   -2.2   0.1       8.2   6.1e+03      18      27 ..     140     149 ..     133     159 .. 0.59
   4 ?    6.3   0.0     0.016        12       7      33 ..     179     205 ..     175     206 .. 0.90
   5 !   11.7   0.0    0.0003      0.23      11      33 ..     218     240 ..     215     241 .. 0.91
   6 ?   -1.2   0.0         4     3e+03      18      33 ..     329     344 ..     327     345 .. 0.88
   7 ?    5.0   0.0     0.041        31       4      28 ..     349     373 ..     347     377 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00023
       TPR_2  8 GlayyklgdyeeAleafekAleldPnn 34
                ++++++ g + +Al++f++A++ dP+n
  EEA19744.1 38 AKSHLATGSPRDALAYFDAAVARDPTN 64
                78999********************98 PP

  == domain 2  score: 18.2 bits;  conditional E-value: 2.4e-06
       TPR_2  5 ynlGlayyklgdyeeAleafekAleldPn 33
                +++G  y+ lg+  +A+++f+++lel P+
  EEA19744.1 69 FQRGATYLSLGRDTQAIDDFNRVLELKPD 97
                89**************************8 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 8.2
       TPR_2  18 eeAleafekA 27 
                 + A++a e+A
  EEA19744.1 140 QTAEKAAEQA 149
                 4455555555 PP

  == domain 4  score: 6.3 bits;  conditional E-value: 0.016
       TPR_2   7 lGlayyklgdyeeAleafekAleldPn 33 
                 +  + +++gd +eAl ++   l++ P+
  EEA19744.1 179 RSHCRFEKGDIQEALGDLAHILQISPG 205
                 678899******************996 PP

  == domain 5  score: 11.7 bits;  conditional E-value: 0.0003
       TPR_2  11 yyklgdyeeAleafekAleldPn 33 
                  y lgdye+A++  +k+l  dP+
  EEA19744.1 218 FYSLGDYERAIAQIRKCLHSDPD 240
                 699***************99998 PP

  == domain 6  score: -1.2 bits;  conditional E-value: 4
       TPR_2  18 eeAleafekAleldPn 33 
                 ++A+ ++   l+l P+
  EEA19744.1 329 KKAKTYCADILQLKPH 344
                 79***********997 PP

  == domain 7  score: 5.0 bits;  conditional E-value: 0.041
       TPR_2   4 lynlGlayyklgdyeeAleafekAl 28 
                 l ++++ y+  +++e+A++ +  A 
  EEA19744.1 349 LLYQAQTYIDEDEFERAINTLTTAK 373
                 7799**************9988875 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.4   0.0    0.0027         2      10      34 .]      40      64 ..      34      64 .. 0.88
   2 !   25.6   0.0   9.6e-09   7.2e-06       5      34 .]      69      98 ..      66      98 .. 0.95
   3 ?    1.8   0.0      0.32   2.4e+02      10      32 ..     182     204 ..     181     206 .. 0.82
   4 !   11.8   0.0   0.00021      0.16      10      33 ..     217     240 ..     216     241 .. 0.93
   5 ?   -1.7   0.0         4     3e+03      18      33 ..     329     344 ..     324     345 .. 0.85
   6 ?    1.6   0.0      0.36   2.7e+02       6      30 ..     351     375 ..     348     379 .. 0.82

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0027
                HHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1 10 ayfklgkydeAleyyekALelnPnn 34
                 ++  g + +Al+y++ A+  +P+n
  EEA19744.1 40 SHLATGSPRDALAYFDAAVARDPTN 64
                567778899**************98 PP

  == domain 2  score: 25.6 bits;  conditional E-value: 9.6e-09
                HHHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1  5 ynlGnayfklgkydeAleyyekALelnPnn 34
                +++G++y++lg+  +A+++++++Lel P++
  EEA19744.1 69 FQRGATYLSLGRDTQAIDDFNRVLELKPDF 98
                689*************************97 PP

  == domain 3  score: 1.8 bits;  conditional E-value: 0.32
                 HHHHTT-HHHHHHHHHHHHHHST CS
       TPR_1  10 ayfklgkydeAleyyekALelnP 32 
                 + f++g+ +eAl +    L++ P
  EEA19744.1 182 CRFEKGDIQEALGDLAHILQISP 204
                 77999******988888888777 PP

  == domain 4  score: 11.8 bits;  conditional E-value: 0.00021
                 HHHHTT-HHHHHHHHHHHHHHSTT CS
       TPR_1  10 ayfklgkydeAleyyekALelnPn 33 
                 ++++lg+y+ A++  +k+L  +P+
  EEA19744.1 217 LFYSLGDYERAIAQIRKCLHSDPD 240
                 689****************99998 PP

  == domain 5  score: -1.7 bits;  conditional E-value: 4
                 HHHHHHHHHHHHHSTT CS
       TPR_1  18 deAleyyekALelnPn 33 
                 ++A  y+   L+l P+
  EEA19744.1 329 KKAKTYCADILQLKPH 344
                 7999999999999997 PP

  == domain 6  score: 1.6 bits;  conditional E-value: 0.36
                 HHHHHHHHTT-HHHHHHHHHHHHHH CS
       TPR_1   6 nlGnayfklgkydeAleyyekALel 30 
                   +++y    +++ A+     A e+
  EEA19744.1 351 YQAQTYIDEDEFERAINTLTTAKEH 375
                 56899***********988888765 PP

>> TPR_9  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.6   0.3   5.7e-08   4.2e-05       6      71 ..      42     107 ..      39     150 .. 0.91
   2 !   12.3   0.0   0.00019      0.14       8      61 ..     152     205 ..     145     212 .. 0.85
   3 ?    5.7   0.0     0.023        17      38      63 ..     217     242 ..     216     247 .. 0.89
   4 !    8.8   0.0    0.0024       1.8      11      65 ..     328     382 ..     323     390 .. 0.84

  Alignments for each domain:
  == domain 1  score: 23.6 bits;  conditional E-value: 5.7e-08
       TPR_9   6 ireedweralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalapdapdaeairaq 71 
                 +       ala+ +  ++ +P     ++ RG  +  lG+  +A++d+++ l+l pd + a + r++
  EEA19744.1  42 LATGSPRDALAYFDAAVARDPTNYLTIFQRGATYLSLGRDTQAIDDFNRVLELKPDFDGALLQRSR 107
                 56666788***********************************************76655555544 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 0.00019
       TPR_9   8 eedweralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalapd 61 
                 + dwe +   +   ++ a+ +  +rr R  ++++ G++++Al dL + l+++p 
  EEA19744.1 152 KGDWETCVSQSSVAIMKASVALNLRRLRSHCRFEKGDIQEALGDLAHILQISPG 205
                 56777777777777777889999***************************9994 PP

  == domain 3  score: 5.7 bits;  conditional E-value: 0.023
       TPR_9  38 llaqlGclsaAladLeaylalapdap 63 
                 l + lG+++ A+a    +l+ +pd  
  EEA19744.1 217 LFYSLGDYERAIAQIRKCLHSDPDSK 242
                 6799*******************976 PP

  == domain 4  score: 8.8 bits;  conditional E-value: 0.0024
       TPR_9  11 weralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalapdapda 65 
                 + +a  ++  +l+l+P++ + ++  ++ +   + ++ A++ L ++ ++  + +++
  EEA19744.1 328 SKKAKTYCADILQLKPHSLHGLLYQAQTYIDEDEFERAINTLTTAKEHHQSSREV 382
                 5678889999*********************************999887655544 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.3   0.1   0.00015      0.12       8      35 ..      38      65 ..      34      70 .. 0.89
   2 !   13.9   0.0   9.9e-05     0.074       6      43 ..      70     107 ..      66     108 .. 0.92
   3 ?    1.1   0.1       1.3   9.3e+02      11      31 ..     133     153 ..     132     160 .. 0.80
   4 ?    1.7   0.0      0.85   6.3e+02       6      39 ..     178     211 ..     172     215 .. 0.78
   5 ?    7.0   0.0     0.016        12      10      34 ..     217     241 ..     207     244 .. 0.83
   6 ?    0.1   0.0       2.8   2.1e+03      16      43 ..     327     354 ..     323     355 .. 0.82
   7 ?    5.7   0.0     0.042        31       4      41 ..     349     386 ..     346     391 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 0.00015
      TPR_14  8 aeallalGdpdeAiallrralalaPdda 35
                a+ +la G p++A+a++++a+a++P++ 
  EEA19744.1 38 AKSHLATGSPRDALAYFDAAVARDPTNY 65
                677999*******************985 PP

  == domain 2  score: 13.9 bits;  conditional E-value: 9.9e-05
      TPR_14   6 alaeallalGdpdeAiallrralalaPddaeawlllaq 43 
                 ++++ +l lG+  +Ai+ ++r+l+l Pd++ a+l+  +
  EEA19744.1  70 QRGATYLSLGRDTQAIDDFNRVLELKPDFDGALLQRSR 107
                 7899****************************998766 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 1.3
      TPR_14  11 llalGdpdeAiallrralala 31 
                 + +l++ ++A++++++a a++
  EEA19744.1 133 YVELDEAQTAEKAAEQAEAKG 153
                 567889999999999998864 PP

  == domain 4  score: 1.7 bits;  conditional E-value: 0.85
      TPR_14   6 alaeallalGdpdeAiallrralalaPddaeawl 39 
                 ++ +  ++ Gd +eA+  l  +l+  P++ e +l
  EEA19744.1 178 LRSHCRFEKGDIQEALGDLAHILQISPGSVEPHL 211
                 4455557889****************99987665 PP

  == domain 5  score: 7.0 bits;  conditional E-value: 0.016
      TPR_14  10 allalGdpdeAiallrralalaPdd 34 
                 +++ lGd+++Aia  r++l  +Pd+
  EEA19744.1 217 LFYSLGDYERAIAQIRKCLHSDPDS 241
                 46799*************9999986 PP

  == domain 6  score: 0.1 bits;  conditional E-value: 2.8
      TPR_14  16 dpdeAiallrralalaPddaeawlllaq 43 
                 + ++A +++ ++l+l P ++  +l+ aq
  EEA19744.1 327 NSKKAKTYCADILQLKPHSLHGLLYQAQ 354
                 567999***********99877777666 PP

  == domain 7  score: 5.7 bits;  conditional E-value: 0.042
      TPR_14   4 llalaeallalGdpdeAiallrralalaPddaeawlll 41 
                 ll  a+ +   +++++Ai+ l  a +++ +++e++ ll
  EEA19744.1 349 LLYQAQTYIDEDEFERAINTLTTAKEHHQSSREVQELL 386
                 67889*******************99999999998665 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0      0.16   1.2e+02       8      34 .]      38      64 ..      32      64 .. 0.86
   2 !   16.4   0.0     1e-05    0.0075       5      33 ..      69      97 ..      67      98 .. 0.94
   3 ?    0.4   0.0       1.4     1e+03       5      17 ..     184     196 ..     178     204 .. 0.61
   4 !   14.7   0.0   3.6e-05     0.027       6      33 ..     212     240 ..     207     241 .. 0.84
   5 ?   -0.7   0.0         3   2.2e+03      17      32 ..     328     343 ..     327     345 .. 0.87
   6 ?    3.2   0.0      0.17   1.3e+02       8      27 ..     353     372 ..     352     374 .. 0.89

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.16
                HHHHHHTT-HHHHHHHHHHHHHHHHH. CS
       TPR_8  8 gsiylklgdyeeAkeyyekaleldpdn 34
                ++ +l +g    A +y+  a+  dp+n
  EEA19744.1 38 AKSHLATGSPRDALAYFDAAVARDPTN 64
                677888999999************986 PP

  == domain 2  score: 16.4 bits;  conditional E-value: 1e-05
                HHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8  5 ynlgsiylklgdyeeAkeyyekaleldpd 33
                ++ g +yl+lg+  +A+  ++++lel+pd
  EEA19744.1 69 FQRGATYLSLGRDTQAIDDFNRVLELKPD 97
                78899***********************8 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 1.4
                 HHHHHHHHHTT-H CS
       TPR_8   5 ynlgsiylklgdy 17 
                 + +g+i + lgd+
  EEA19744.1 184 FEKGDIQEALGDL 196
                 4555666666654 PP

  == domain 4  score: 14.7 bits;  conditional E-value: 3.6e-05
                 HHHHHH.HHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   6 nlgsiy.lklgdyeeAkeyyekaleldpd 33 
                 +++s++  +lgdye A++ ++k+l  dpd
  EEA19744.1 212 QISSTLfYSLGDYERAIAQIRKCLHSDPD 240
                 666666699***************99997 PP

  == domain 5  score: -0.7 bits;  conditional E-value: 3
                 HHHHHHHHHHHHHHHH CS
       TPR_8  17 yeeAkeyyekaleldp 32 
                  ++Ak y+   l+l+p
  EEA19744.1 328 SKKAKTYCADILQLKP 343
                 689*****99999999 PP

  == domain 6  score: 3.2 bits;  conditional E-value: 0.17
                 HHHHHHTT-HHHHHHHHHHH CS
       TPR_8   8 gsiylklgdyeeAkeyyeka 27 
                 +++y++  ++e A+ ++  a
  EEA19744.1 353 AQTYIDEDEFERAINTLTTA 372
                 89************999776 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.0      0.19   1.4e+02       6      33 ..      38      63 ..      33      65 .. 0.83
   2 !    8.7   0.0    0.0025       1.9       3      34 ..      69     100 ..      67     102 .. 0.87
   3 ?   -2.4   0.0       9.1   6.8e+03      12      19 ..     186     193 ..     179     200 .. 0.63
   4 !   10.3   0.0   0.00081       0.6       9      35 ..     218     242 ..     211     243 .. 0.86
   5 ?    6.7   0.1     0.011       8.6       2      27 ..     349     372 ..     349     382 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.19
       TPR_7  6 arlysrlGdyeeAielyeqsLaltkdpe 33
                a  + + G  ++A+ ++ +  a+++dp+
  EEA19744.1 38 AKSHLATGSPRDALAYFDA--AVARDPT 63
                66777888889********..*****97 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.0025
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLaltkdped 34 
                 ++ + +y +lG+  +Ai+ + ++L+l  d ++
  EEA19744.1  69 FQRGATYLSLGRDTQAIDDFNRVLELKPDFDG 100
                 56789*****************9999988766 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 9.1
       TPR_7  12 lGdyeeAi 19 
                  Gd +eA+
  EEA19744.1 186 KGDIQEAL 193
                 56666665 PP

  == domain 4  score: 10.3 bits;  conditional E-value: 0.00081
       TPR_7   9 ysrlGdyeeAielyeqsLaltkdpeda 35 
                 + +lGdye+Ai   ++   l++dp+ +
  EEA19744.1 218 FYSLGDYERAIAQIRK--CLHSDPDSK 242
                 5679************..999999865 PP

  == domain 5  score: 6.7 bits;  conditional E-value: 0.011
       TPR_7   2 LlnLarlysrlGdyeeAielyeqsLa 27 
                 Ll+ a++y ++ ++e+Ai  ++   a
  EEA19744.1 349 LLYQAQTYIDEDEFERAINTLTT--A 372
                 6788***************9988..4 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0   1.6e-06    0.0012       4      66 ..      38      97 ..      35      98 .. 0.94
   2 ?   -0.6   0.3       2.9   2.2e+03       7      27 ..     133     153 ..     131     154 .. 0.80
   3 ?    1.3   0.0      0.73   5.5e+02      40      56 ..     179     196 ..     168     206 .. 0.64
   4 ?    6.6   0.0     0.016        12       7      29 ..     218     240 ..     215     247 .. 0.62
   5 ?   -0.6   0.0       2.8   2.1e+03       3      26 ..     352     375 ..     351     398 .. 0.72

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 1.6e-06
      TPR_16  4 araalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraalraapd 66
                a+++l+ g ++dA+a+++aa++rd   P ++   + +g  +l +gr + A++ +++ l+  pd
  EEA19744.1 38 AKSHLATGSPRDALAYFDAAVARD---PTNYLTIFQRGATYLSLGRDTQAIDDFNRVLELKPD 97
                8899********************...98888*******************999999999886 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 2.9
      TPR_16   7 alragdyddAaaaleaalkrd 27 
                 ++++ + + A++a+e+a +++
  EEA19744.1 133 YVELDEAQTAEKAAEQAEAKG 153
                 677778889999999998876 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.73
      TPR_16  40 lgdaalrqgrlaeAa.al 56 
                 +  +++++g+ +eA+ +l
  EEA19744.1 179 RSHCRFEKGDIQEALgDL 196
                 445667777777776333 PP

  == domain 4  score: 6.6 bits;  conditional E-value: 0.016
      TPR_16   7 alragdyddAaaaleaalkrdps 29 
                 ++ +gdy++A+a+ +  l +dp+
  EEA19744.1 218 FYSLGDYERAIAQIRKCLHSDPD 240
                 56666666666666666666633 PP

  == domain 5  score: -0.6 bits;  conditional E-value: 2.8
      TPR_16   3 laraalragdyddAaaaleaalkr 26 
                 +a+ +++  ++++A++ l++a + 
  EEA19744.1 352 QAQTYIDEDEFERAINTLTTAKEH 375
                 688899999999999999666444 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0      0.24   1.8e+02       6      49 ..      48      91 ..      32     103 .. 0.71
   2 ?   -1.3   0.0       3.5   2.6e+03      37      77 ..     153     194 ..     142     199 .. 0.76
   3 !   11.5   0.0   0.00035      0.26      31      63 ..     216     249 ..     208     266 .. 0.84
   4 !   16.1   1.4   1.3e-05    0.0098       9      74 ..     333     400 ..     325     408 .. 0.79
   5 ?    2.0   0.1      0.33   2.4e+02      26      58 ..     385     418 ..     379     435 .. 0.76
   6 ?   -0.7   0.0       2.2   1.7e+03      39      79 ..     416     456 ..     412     458 .. 0.72

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.24
                HHHHHHHHHHH.HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCT CS
      ANAPC3  6 knAiflaerllaaetespedayllAlclylngqykrAyellrka 49
                ++A+ +++ ++a+++ ++  ++  + +++++g+ ++A++ +++ 
  EEA19744.1 48 RDALAYFDAAVARDPTNYLTIFQRGATYLSLGRDTQAIDDFNRV 91
                46777777777777777777777777777777777777766665 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 3.5
                 T-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHH CS
      ANAPC3  37 gqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAia 77 
                 g+++++    + a  ++s  l+ r l  +c ++ + ++eA+ 
  EEA19744.1 153 GDWETCVSQSSVAiMKASVALNLRRLRSHCRFEKGDIQEALG 194
                 677777777777777777777788888888888888888875 PP

  == domain 3  score: 11.5 bits;  conditional E-value: 0.00035
                 HHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHH CS
      ANAPC3  31 lclylngqykrAyellrka.klnskslgcrylfA 63 
                   +y++g+y+rA+  +rk+  +++ s+ c  lf 
  EEA19744.1 216 TLFYSLGDYERAIAQIRKClHSDPDSKSCSRLFR 249
                 568**************************99986 PP

  == domain 4  score: 16.1 bits;  conditional E-value: 1.3e-05
                 HHHHHHHH.HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCTSHHHC-H...HHHHHHHHHHHHTT-HHH CS
      ANAPC3   9 iflaerllaaetespedayllAlclylngqykrAyellrkaklnsksl...gcrylfAqcllkLkkyee 74 
                   +a+ l+  +++s+  +++ A+++    +++rA++ l +ak+ ++s    + ++ +Aq+llk +k ++
  EEA19744.1 333 TYCADILQ-LKPHSLHGLLYQAQTYIDEDEFERAINTLTTAKEHHQSSrevQELLQKAQVLLKRSKQKD 400
                 44566666.9*******************************7777777777778888888888777665 PP

  == domain 5  score: 2.0 bits;  conditional E-value: 0.33
                 HHHHHHHHHHTT-HHHHHHHHHCT.SHHHC-HHH CS
      ANAPC3  26 ayllAlclylngqykrAyellrka.klnskslgc 58 
                 ++ +A++l+++++ k  y++l  + + ++++++ 
  EEA19744.1 385 LLQKAQVLLKRSKQKDYYKILGVSrDADDRTIKR 418
                 5667999999999999999998886666666544 PP

  == domain 6  score: -0.7 bits;  conditional E-value: 2.2
                 HHHHHHHHHCTSHHHC-HHHHHHHHHHHHHTT-HHHHHHHH CS
      ANAPC3  39 ykrAyellrkaklnskslgcrylfAqcllkLkkyeeAiaaL 79 
                  krAy+ l k    +k +   + +  +  k+ +++eA+ +L
  EEA19744.1 416 IKRAYRQLTKIHHPDKAMSQGVSKEDAETKMASINEAYEVL 456
                 68888888888666666666666777777888888888877 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.0      0.14     1e+02      13      42 .]      50      79 ..      48      79 .. 0.91
   2 !   15.0   0.0     2e-05     0.015       2      31 ..      73     102 ..      72     105 .. 0.88
   3 ?    0.5   0.0      0.65   4.9e+02       5      31 ..     184     210 ..     182     213 .. 0.75
   4 !    7.6   0.0     0.004         3       4      21 ..     218     235 ..     216     241 .. 0.77
   5 ?   -0.4   0.0       1.3   9.7e+02       3      20 ..     355     372 ..     353     374 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.14
      TPR_11 13 AieaYkkAlkldPdnaeayynLGlayykqG 42
                A++ + +A++ dP+n    + +G++y+ +G
  EEA19744.1 50 ALAYFDAAVARDPTNYLTIFQRGATYLSLG 79
                7888899*******************9988 PP

  == domain 2  score: 15.0 bits;  conditional E-value: 2e-05
      TPR_11   2 dayyeqGkyeeAieaYkkAlkldPdnaeay 31 
                   y ++G+ ++Ai ++++ l+l+Pd+  a+
  EEA19744.1  73 ATYLSLGRDTQAIDDFNRVLELKPDFDGAL 102
                 5799*********************97665 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.65
      TPR_11   5 yeqGkyeeAieaYkkAlkldPdnaeay 31 
                 +e+G++ eA+ ++   l+++P ++e +
  EEA19744.1 184 FEKGDIQEALGDLAHILQISPGSVEPH 210
                 89*******977766667776666666 PP

  == domain 4  score: 7.6 bits;  conditional E-value: 0.004
      TPR_11   4 yyeqGkyeeAieaYkkAl 21 
                 +y++G+ye Ai++ +k l
  EEA19744.1 218 FYSLGDYERAIAQIRKCL 235
                 9**********9866655 PP

  == domain 5  score: -0.4 bits;  conditional E-value: 1.3
      TPR_11   3 ayyeqGkyeeAieaYkkA 20 
                  y +  ++e Ai+ + +A
  EEA19744.1 355 TYIDEDEFERAINTLTTA 372
                 689999******998766 PP

>> TPR_6  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.0      0.06        45       7      32 ..      38      63 ..      33      64 .. 0.91
   2 !    7.5   0.0    0.0097       7.2       4      29 ..      69      94 ..      67      97 .. 0.89
   3 ?    0.5   0.0       1.6   1.2e+03       9      33 .]     182     206 ..     178     206 .. 0.82
   4 !    9.2   0.0    0.0027         2       9      33 .]     217     241 ..     211     241 .. 0.91
   5 ?   -0.7   0.1         4     3e+03       8      29 ..     246     267 ..     245     268 .. 0.84
   6 ?    0.4   0.0       1.8   1.3e+03       9      29 ..     322     341 ..     321     345 .. 0.81
   7 ?    4.4   0.0     0.092        68       3      26 ..     349     372 ..     347     379 .. 0.87
   8 ?    0.1   0.0       2.2   1.6e+03      15      29 ..     412     426 ..     386     430 .. 0.76

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.06
                HHHHHHHHHHHHHHHHHHHHHHH-TT CS
       TPR_6  7 alsyrklgdtdkAlealerlikeYPd 32
                a+s++++g +++Al++++  + + P+
  EEA19744.1 38 AKSHLATGSPRDALAYFDAAVARDPT 63
                89999999**************9996 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0097
                HHHHHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6  4 yklalsyrklgdtdkAlealerlike 29
                ++++  y++lg+ ++A++ ++r+++ 
  EEA19744.1 69 FQRGATYLSLGRDTQAIDDFNRVLEL 94
                889999***99************986 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 1.6
                 HHHHHHHHHHHHHHHHHHHHH-TT- CS
       TPR_6   9 syrklgdtdkAlealerlikeYPdS 33 
                 ++++ gd ++Al  l  +++  P+S
  EEA19744.1 182 CRFEKGDIQEALGDLAHILQISPGS 206
                 889988*****99888888877776 PP

  == domain 4  score: 9.2 bits;  conditional E-value: 0.0027
                 HHHHHHHHHHHHHHHHHHHHH-TT- CS
       TPR_6   9 syrklgdtdkAlealerlikeYPdS 33 
                 ++++lgd+++A++  ++++ + PdS
  EEA19744.1 217 LFYSLGDYERAIAQIRKCLHSDPDS 241
                 678899******************9 PP

  == domain 5  score: -0.7 bits;  conditional E-value: 4
                 HHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   8 lsyrklgdtdkAlealerlike 29 
                 +++rk +++ k+l  l+++ ++
  EEA19744.1 246 RLFRKEKQYVKSLNKLQEFKEK 267
                 5788888**********99876 PP

  == domain 6  score: 0.4 bits;  conditional E-value: 1.8
                 HHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   9 syrklgdtdkAlealerlike 29 
                  yr++ ++ kA+++  ++++ 
  EEA19744.1 322 IYRAM-NSKKAKTYCADILQL 341
                 6999*.*******99888875 PP

  == domain 7  score: 4.4 bits;  conditional E-value: 0.092
                 HHHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   3 lyklalsyrklgdtdkAlealerl 26 
                 l+++a+ y+  ++ ++A+ +l   
  EEA19744.1 349 LLYQAQTYIDEDEFERAINTLTTA 372
                 899******999*******99876 PP

  == domain 8  score: 0.1 bits;  conditional E-value: 2.2
                 HHHHHHHHHHHHHHH CS
       TPR_6  15 dtdkAlealerlike 29 
                 d ++ ++a+++l k 
  EEA19744.1 412 DDRTIKRAYRQLTKI 426
                 566778899999987 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   4.3e-05     0.032       2      33 ..      54      85 ..      47      86 .. 0.94
   2 ?   -1.2   0.0       4.6   3.5e+03       2      23 ..      88     109 ..      87     120 .. 0.73
   3 ?    4.8   0.0     0.056        42       6      33 ..     200     228 ..     196     229 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 4.3e-05
      TPR_17  2 ylkaleldPnnadaynnLAelllknGdlmtAr 33
                +  a+++dP+n    ++++ ++l++G+  +A+
  EEA19744.1 54 FDAAVARDPTNYLTIFQRGATYLSLGRDTQAI 85
                7899**********************999886 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 4.6
      TPR_17   2 ylkaleldPnnadaynnLAell 23 
                 + ++lel P+   a+ ++ ++ 
  EEA19744.1  88 FNRVLELKPDFDGALLQRSRIK 109
                 6899*****9988887776665 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.056
      TPR_17   6 leldPnnadaynnLAell.lknGdlmtAr 33 
                 l++ P +++++ +   +l +++Gd+++A+
  EEA19744.1 200 LQISPGSVEPHLQISSTLfYSLGDYERAI 228
                 78899999999***998758********8 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.0   8.9e-05     0.066      10      75 ..      38      95 ..      30      97 .. 0.86
   2 ?   -1.9   0.0       5.7   4.3e+03      26      41 ..     142     155 ..     135     167 .. 0.62
   3 !    8.0   0.1    0.0048       3.6       8      72 ..     178     235 ..     170     236 .. 0.73
   4 ?   -0.5   0.2       2.1   1.6e+03      10      35 ..     353     378 ..     345     393 .. 0.66

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 8.9e-05
      TPR_12 10 aavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaia 75
                a  +++ g   +Al+++++a+++      p+++l   t +  g +y+ lgr  +A++ ++++l+++
  EEA19744.1 38 AKSHLATGSPRDALAYFDAAVARD-----PTNYL---TIFQRGATYLSLGRDTQAIDDFNRVLELK 95
                677888999999999999998888.....88866...6999**********************997 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 5.7
      TPR_12  26 lekaleiarrllGpdh 41 
                  eka e+a++   +d+
  EEA19744.1 142 AEKAAEQAEAK--GDW 155
                 46666666666..555 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.0048
      TPR_12   8 nlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrly.ralgryeeAlelleeal 72 
                  + ++ ++ g+ +eAl  l + l+i      p +   ++    ++ ++ + lg+ye A++  +++l
  EEA19744.1 178 LRSHCRFEKGDIQEALGDLAHILQIS-----PGS---VEPHLQISSTLfYSLGDYERAIAQIRKCL 235
                 467889999****************9.....433...55555666664378899998888777765 PP

  == domain 4  score: -0.5 bits;  conditional E-value: 2.1
      TPR_12  10 aavlrrlgrydeAlellekaleiarr 35 
                 a+++    +++ A+  l +a e +++
  EEA19744.1 353 AQTYIDEDEFERAINTLTTAKEHHQS 378
                 55566666666666666666666554 PP

>> HrpB1_HrpK  Bacterial type III secretion protein (HrpB1_HrpK)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       3.3   2.5e+03      10      45 ..      30      65 ..      27     117 .. 0.68
   2 ?   -3.0   0.0       6.9   5.2e+03      20      66 ..      78     120 ..      66     131 .. 0.68
   3 ?   -2.3   0.0       4.3   3.2e+03      41      82 ..     203     245 ..     171     249 .. 0.54
   4 !   16.4   0.0   6.9e-06    0.0052       5      86 ..     306     387 ..     304     419 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 3.3
  HrpB1_HrpK 10 lvggLievlslalasedtedaellLdalrvLrPeva 45
                 v+ Li+ +   la++ + da +  da  +  P + 
  EEA19744.1 30 PVASLISSAKSHLATGSPRDALAYFDAAVARDPTNY 65
                577888888888888888888877777665555544 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 6.9
  HrpB1_HrpK  20 lalasedtedaellLdalrvLrPevaeldllegvlliergrweeAlr 66 
                 l+ ++++++d +++L+    L+P +  + l    +  +  +w++A  
  EEA19744.1  78 LGRDTQAIDDFNRVLE----LKPDFDGALLQRSRIKSRSADWTGAKE 120
                 5555566666666664....677777777777777777777777755 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 4.3
  HrpB1_HrpK  41 rPevaeldl.legvlliergrweeAlrlLreveaeasgtpyak 82 
                 +P  +e +l +   l  + g++e A+  +r+  ++ +  + ++
  EEA19744.1 203 SPGSVEPHLqISSTLFYSLGDYERAIAQIRKCLHSDPDSKSCS 245
                 3433333321344445555666666666666665555555555 PP

  == domain 4  score: 16.4 bits;  conditional E-value: 6.9e-06
  HrpB1_HrpK   5 qcskelvggLievlslalasedtedaellLdalrvLrPevaeldllegvlliergrweeAlrlLreveaeasgtpyakaLlA 86 
                 ++++el + Liev+ +  ++ +++ a++  + +  L+P+     l++++ +i + ++e A+ +L + ++++++   +++Ll 
  EEA19744.1 306 NAPNELYASLIEVTCEIYRAMNSKKAKTYCADILQLKPHSLHGLLYQAQTYIDEDEFERAINTLTTAKEHHQSSREVQELLQ 387
                 56789999**************************************************************999999998875 PP

>> PknG_TPR  Protein kinase G tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.0   0.00056      0.42      91     157 ..      28      94 ..       9      98 .. 0.88
   2 ?    1.1   0.0      0.17   1.3e+02     134     171 ..     179     216 ..     136     239 .. 0.84
   3 ?   -1.1   0.0      0.81   6.1e+02     246     301 ..     355     410 ..     310     430 .. 0.61

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00056
                 CC-SHHHHHHHHHHHHCT-HHHHHHHHHHHHHHH---HHHHHHHHHHHHHHT-HHHHHHHHHHHHHH CS
    PknG_TPR  91 seslevpLaevrahldlGdveearelLdeleeeveedWrldWyrglaeLlegdyeeAaaeFdevlaa 157
                    +   +  ++ hl  G +++a +++d+  ++ ++++ + + rg + L+ g+ ++A+++F++vl++
  EEA19744.1  28 DLPVASLISSAKSHLATGSPRDALAYFDAAVARDPTNYLTIFQRGATYLSLGRDTQAIDDFNRVLEL 94 
                 445566677899****************************************************986 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.17
                 HHHHHHHHT-HHHHHHHHHHHHHHSTT-SHHHHHHHHH CS
    PknG_TPR 134 rglaeLlegdyeeAaaeFdevlaalpGEiaPklaLAat 171
                 r+ ++  +gd +eA  +  ++l++ pG + P l ++ t
  EEA19744.1 179 RSHCRFEKGDIQEALGDLAHILQISPGSVEPHLQISST 216
                 55677788888999999999999999999998887766 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 0.81
                 ----HHHHHHHHHHHHTS-TTSCCHHHHHHHHHHHHHHHCTT---SSSEETTEESS CS
    PknG_TPR 246 aeldeadlreaarrveaLpedeeralqlrvlVlgaALdWlragkassetlLgvpft 301
                   +de+++++a + +++ +e+++ + +++ l + a +   r++++   ++Lgv+ +
  EEA19744.1 355 TYIDEDEFERAINTLTTAKEHHQSSREVQELLQKAQVLLKRSKQKDYYKILGVSRD 410
                 34555556666665555555555555555554444444333444444566666554 PP

>> TPR_20  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.0    0.0025       1.9       8      56 ..      51      99 ..      46     125 .. 0.89
   2 ?    2.1   0.0      0.32   2.4e+02      32      85 ..     183     235 ..     161     238 .. 0.67
   3 ?   -0.4   0.2         2   1.5e+03      29      53 ..     353     377 ..     339     426 .. 0.71
   4 ?   -1.9   0.1         6   4.4e+03      35      55 ..     413     433 ..     375     442 .. 0.59

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0025
      TPR_20  8 laeleaalaanpddldarldlAlallaagryeeAleqLleilkrdrkwe 56
                la ++aa+a +p+++ + ++    +l+ gr  +A++ + ++l+ + +++
  EEA19744.1 51 LAYFDAAVARDPTNYLTIFQRGATYLSLGRDTQAIDDFNRVLELKPDFD 99
                677899*******************************999999888774 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.32
      TPR_20  32 llaagryeeAleqLleilkrdrkweddaarkqllkifealgsqdplvakyRrkL 85 
                  +++g+ +eAl  L +il+   +  + +  +    +f +lg+ + ++a+ R+ L
  EEA19744.1 183 RFEKGDIQEALGDLAHILQISPGSVEPHL-QISSTLFYSLGDYERAIAQIRKCL 235
                 56788889999999988887766533322.333456666666666666666655 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 2
      TPR_20  29 AlallaagryeeAleqLleilkrdr 53 
                 A+ ++ + + e A++ L +  ++++
  EEA19744.1 353 AQTYIDEDEFERAINTLTTAKEHHQ 377
                 6777777777777777766544443 PP

  == domain 4  score: -1.9 bits;  conditional E-value: 6
      TPR_20  35 agryeeAleqLleilkrdrkw 55 
                     + A  qL +i   d++ 
  EEA19744.1 413 DRTIKRAYRQLTKIHHPDKAM 433
                 334455555555555555555 PP

>> KORA  TrfB plasmid transcriptional repressor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0       4.3   3.2e+03       3      37 ..     251     286 ..     250     290 .. 0.74
   2 ?   13.2   0.3   0.00011     0.082       3      67 ..     359     431 ..     357     443 .. 0.73

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 4.3
        KORA   3 eeeFeeiikgleelaeq.tveiargvLVegkkqadv 37 
                 e+++ + +++l+e++e+     a ++LV  k  + +
  EEA19744.1 251 EKQYVKSLNKLQEFKEKrKFTNAINILVGTKDESGM 286
                 688888899999998751557788999988877766 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 0.00011
        KORA   3 eeeFeeiikgleelae...qtveiar.....gvLVegkkqadvatelgltkqavsqavkrvwaahaereepag 67 
                 e eFe++i+ l + +e   + +e+       +vL +  kq+d+ + lg+++ a  + +kr++   ++ + p++
  EEA19744.1 359 EDEFERAINTLTTAKEhhqSSREVQEllqkaQVLLKRSKQKDYYKILGVSRDADDRTIKRAYRQLTKIHHPDK 431
                 678888888885444311123333212222389***************************9998888777765 PP

>> GCIP  Grap2 and cyclin-D-interacting
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.1      0.98   7.3e+02     155     221 ..     135     202 ..      79     233 .. 0.67
   2 ?   13.3   0.6   6.1e-05     0.045     108     190 ..     263     397 ..     257     452 .. 0.78

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.98
                 --------.-----TTS--HHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHH--TT...-HHHHHHHHHH CS
        GCIP 155 dldddede.ergnqdrklseeekevikavlkllkatval.lkklsrsiteegkkdskeqvaqldklldl 221
                 +ld+ ++  ++++q +   + e  v + +++++ka+val l++l+ s  + +k d +e +  l ++l++
  EEA19744.1 135 ELDEAQTAeKAAEQAEAKGDWETCVSQSSVAIMKASVALnLRRLR-SHCRFEKGDIQEALGDLAHILQI 202
                 333333334555666666667777778888888888877344443.33335566666666666666655 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 6.1e-05
                 TTTTS-S.SHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.................................................S----------- CS
        GCIP 108 alkklpk.dNktAilraieevlglvkDaleEmkellee.............................................edeeedededdlddde 160
                 ++k+  k +N   il+  +  +g+++D+ e++ke+ e+                                                   ++++++d+de
  EEA19744.1 263 EFKEKRKfTNAINILVGTKDESGMIDDVKEDVKEAREAgyihpnapnelyaslievtceiyramnskkaktycadilqlkphsLHGLLYQAQTYIDEDE 361
                 6777777799999*******************************************************9999999999999985567778888899998 PP

                 --......-----TTS--HHHHHHHHHHHHHHHHHH CS
        GCIP 161 de......ergnqdrklseeekevikavlkllkatv 190
                  e      +++++  + s e +e++++++ llk ++
  EEA19744.1 362 FEraintlTTAKEHHQSSREVQELLQKAQVLLKRSK 397
                 886665555555555666666666666666664333 PP

>> Fis1_TPR_C  Fis1 C-terminal tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       6.6   4.9e+03      19      34 ..      49      64 ..      48      65 .. 0.89
   2 ?   -2.3   0.0       6.3   4.7e+03      24      45 ..      88     109 ..      75     113 .. 0.71
   3 ?    8.2   0.0    0.0033       2.5      12      40 ..     219     247 ..     218     257 .. 0.88
   4 ?    2.9   0.0      0.16   1.2e+02      12      33 ..     323     344 ..     322     348 .. 0.87
   5 ?   -1.0   0.0       2.6     2e+03      15      29 ..     373     387 ..     360     392 .. 0.56

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 6.6
                HHHHHHHHHHHHTTS- CS
  Fis1_TPR_C 19 eArryvdalLeiEPen 34
                +A+ y da  + +P n
  EEA19744.1 49 DALAYFDAAVARDPTN 64
                6999******999998 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 6.3
                 HHHHHHHTTS-HHHHHHHHHHH CS
  Fis1_TPR_C  24 vdalLeiEPenrQaqsLkelie 45 
                  +++Le+ P++  a+  ++ i+
  EEA19744.1  88 FNRVLELKPDFDGALLQRSRIK 109
                 5788999999988776666655 PP

  == domain 3  score: 8.2 bits;  conditional E-value: 0.0033
                 HHHT-HHHHHHHHHHHHHHTTS-HHHHHH CS
  Fis1_TPR_C  12 yklgeYseArryvdalLeiEPenrQaqsL 40 
                 y lg+Y++A   ++ +L+ +P+ +    L
  EEA19744.1 219 YSLGDYERAIAQIRKCLHSDPDSKSCSRL 247
                 679******************98876666 PP

  == domain 4  score: 2.9 bits;  conditional E-value: 0.16
                 HHHT-HHHHHHHHHHHHHHTTS CS
  Fis1_TPR_C  12 yklgeYseArryvdalLeiEPe 33 
                 y+  + ++A+ y+  +L++ P 
  EEA19744.1 323 YRAMNSKKAKTYCADILQLKPH 344
                 6777789***********9996 PP

  == domain 5  score: -1.0 bits;  conditional E-value: 2.6
                 T-HHHHHHHHHHHHH CS
  Fis1_TPR_C  15 geYseArryvdalLe 29 
                 +e+ ++ r v+ lL+
  EEA19744.1 373 KEHHQSSREVQELLQ 387
                 455555555555555 PP

>> Med15  ARC105 or Med15 subunit of Mediator complex non-fungal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00018      0.13     517     568 ..     413     463 ..     408     466 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00018
       Med15 517 eqLYrekyrqltkYiePlkrmiakiendeddikdlskmkklLeilsnPssri 568
                 ++  +  yrqltk   P k m ++++++ d   +++++++  e+ls+P  r+
  EEA19744.1 413 DRTIKRAYRQLTKIHHPDKAMSQGVSKE-DAETKMASINEAYEVLSDPELRA 463
                 5666788********************9.7779***************9986 PP

>> HAD_2  Haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.0     0.044        33       4      68 ..      97     161 ..      97     196 .. 0.92
   2 ?    2.5   0.0      0.18   1.4e+02     141     172 ..     270     301 ..     228     303 .. 0.85
   3 ?    2.3   0.2       0.2   1.5e+02      44     148 ..     345     456 ..     313     479 .. 0.61

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.044
       HAD_2   4 DlDgTlldteeliiqafnelleeyglselseeelrkliglslrellrklgeseeeeekieellrk 68 
                 D+Dg ll ++ +   ++  + ++++l +  ++   ++++l+  ++ +k++e+ e ++++e+ +++
  EEA19744.1  97 DFDGALLQRSRIKSRSADWTGAKEDLVKAGKKSSPEYVELDEAQTAEKAAEQAEAKGDWETCVSQ 161
                 9***************************************************9999988877665 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.18
       HAD_2 141 iekaleklklkkeeviyvGDsptDieaakkag 172
                 + +a++ l  +k+e  ++ D + D++ a++ag
  EEA19744.1 270 FTNAINILVGTKDESGMIDDVKEDVKEAREAG 301
                 56777778888999999999999999999998 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.2
       HAD_2  44 slrellrklgeseeeee...kieellrkyneekkk.kevkpydgvkelLeeLkeagyk..lgivTsksreaveekleqlgiesyFdvi....vtsedve 132
                 sl+ ll++++   +e+e    i++l    ++++   +  ++++ ++ lL+  k+++y   lg+  + +++++++  +ql   ++ d+     v++ed+e
  EEA19744.1 345 SLHGLLYQAQTYIDEDEferAINTLTTAKEHHQSSrEVQELLQKAQVLLKRSKQKDYYkiLGVSRDADDRTIKRAYRQLTKIHHPDKAmsqgVSKEDAE 443
                 455555555555554445558888854444444445666788899999999888887434888888888888888888776655444411114455555 PP

       HAD_2 133 kkKPdpeviekalekl 148
                  k    ++i++a e l
  EEA19744.1 444 TK---MASINEAYEVL 456
                 55...66666666655 PP

>> ClpS  ATP-dependent Clp protease adaptor protein ClpS
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0         3   2.2e+03      54      77 ..     326     349 ..     320     351 .. 0.78
   2 ?    9.2   0.1    0.0014         1      32      68 ..     415     451 ..     409     459 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 3
                 E-HHHHHHHHHHHHH......TT- CS
        ClpS  54 gtreiaetkveqverlarreghpL 77 
                 ++ ++a+t+++++ +l+ ++ h+L
  EEA19744.1 326 MNSKKAKTYCADILQLKPHSLHGL 349
                 577899999999999777777777 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.0014
                 -HHHHHHHHHHHHHHSEEEEEEE-HHHHHHHHHHHHH CS
        ClpS  32 skeeAteimlevhreGravvgvgtreiaetkveqver 68 
                 + ++A +  +++h+  +a+ +  ++e+aetk++ +++
  EEA19744.1 415 TIKRAYRQLTKIHHPDKAMSQGVSKEDAETKMASINE 451
                 56899999*************************9998 PP

>> DsrD  Dissimilatory sulfite reductase D (DsrD)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.5      0.15   1.1e+02      15      43 ..     250     278 ..     242     283 .. 0.86
   2 ?    2.8   0.0      0.19   1.4e+02      11      29 ..     327     344 ..     319     347 .. 0.79
   3 ?    1.5   0.2       0.5   3.7e+02      11      42 ..     394     423 ..     382     427 .. 0.70

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.15
                 SS-EEHHHHHHH-TTS-HHHHHHHHHHHH CS
        DsrD  15 KskfYfkDlekalPdakpreiKkvvneLV 43 
                 K k Y+k l+k+   + +r+  +++n LV
  EEA19744.1 250 KEKQYVKSLNKLQEFKEKRKFTNAINILV 278
                 99**********9778889999***9999 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.19
                 SCCCSS-EEHHHHHHH-TT CS
        DsrD  11 kkkkKskfYfkDlekalPd 29 
                 ++ kK+k Y  D+ ++ P 
  EEA19744.1 327 NS-KKAKTYCADILQLKPH 344
                 33.49********999985 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.5
                 SCCCSS-EEHHHHHHH-TTS-HHHHHHHHHHH CS
        DsrD  11 kkkkKskfYfkDlekalPdakpreiKkvvneL 42 
                 k++ K k Y k l     da  r+iK++  +L
  EEA19744.1 394 KRS-KQKDYYKILGVS-RDADDRTIKRAYRQL 423
                 333.777787755554.5*********99888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (522 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1373  (0.0765798); expected 358.6 (0.02)
Passed bias filter:                      725  (0.0404373); expected 358.6 (0.02)
Passed Vit filter:                       103  (0.00574488); expected 17.9 (0.001)
Passed Fwd filter:                        24  (0.00133861); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              24  [number of targets reported over threshold]
# CPU time: 0.67u 0.32s 00:00:00.99 Elapsed: 00:00:00.49
# Mc/sec: 3233.09
//
Query:       EEA19745.1  [L=421]
Description: mitochondrial translation release factor (RF-1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.6e-50  170.5   0.0    1.8e-49  168.3   0.0    2.0  2  PCRF      PCRF domain
    1.6e-33  115.0   1.5    3.3e-33  114.1   1.5    1.5  1  RF-1      RF-1 domain


Domain annotation for each model (and alignments):
>> PCRF  PCRF domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  168.3   0.0     2e-53   1.8e-49      25     193 .]      67     241 ..      43     241 .. 0.94
   2 ?   -0.5   0.0      0.11   9.8e+02      74     115 ..     314     354 ..     277     371 .. 0.68

  Alignments for each domain:
  == domain 1  score: 168.3 bits;  conditional E-value: 2e-53
                 SSTTHHHHHTHHHHHHHHHHHHHTTTHHH...HT.......-S-..-GGGTHHHHHHHHHH..HHHHHT-..SSSTTSEEEEEEEE-SSTHHHHHHHHH CS
        PCRF  25 kklskelaeleeivealeeleealedleeakelle...edeelaelaeeeleelekeleeleeelkklLlpkdendeknaileiraGaGGdeaalfaed 120
                 +k++k+l el+++++a++++++++e+++e+++l++   +d+el++la e+l++++++l  ++++lk+ L+p+++  + +++leir+GaGGdea lfa +
  EEA19745.1  67 TKVAKRLGELAPVAQAVKDWDKTHETITELNSLISdpeTDSELRSLALEDLDQTQTQLPIVSDKLKSALIPRHPFAALPCLLEIRPGAGGDEAGLFAYE 165
                 5899******************************4477999********************************************************** PP

                 HHHHHHHHHHTTT-EEEEEEEEESSS....SEEEEEEEEESTTHHHHHGGG-EEEEEEEE-TTSSS--EEEEEEEE CS
        PCRF 121 LlrmYtryaerkgwkvevldaseeea...gGikevtleiegegaYgkLkfEsGvHRvqRvpetesqgrihTStatV 193
                 LlrmY+++++rkg +++++++  eea     ++e+++eie +g Y+ L++E GvHRvqRvp+te++gr hTS+++V
  EEA19745.1 166 LLRMYQNFCSRKGLRTSIVKQDMEEAisnDRLSEAVVEIETPGSYDILRTEIGVHRVQRVPATEAKGRTHTSAVSV 241
                 ********************99988877779*******************************************98 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.11
                 HHHHHHHHH..HHHHHT-..SSSTTSEEEEEEEE-SSTHHHH CS
        PCRF  74 elekeleeleeelkklLlpkdendeknaileiraGaGGdeaa 115
                 + +++ +++ + l+  L  + ++ +++ ++++r Ga G  a+
  EEA19745.1 314 Q-HANRKKAWQLLRAKLAERRREAREEEMVKLRRGAMGGVAK 354
                 3.3333444467788888888888888888888887555555 PP

>> RF-1  RF-1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.1   1.5   3.6e-37   3.3e-33       5     116 .]     266     375 ..     262     375 .. 0.83

  Alignments for each domain:
  == domain 1  score: 114.1 bits;  conditional E-value: 3.6e-37
                 CE--GGGEEEEEE---SSSSSSGCSSSCEEEEEETTTTEEEEEEECSSSHHHHHHHHHHHHHHHHHHHHHHHCCCCCHTTTTT-.S.-S---S.--ECE CS
        RF-1   5 ieidekdleidtfrssGaGGQnVNktesaVrlthlptgvivvecqeeRsqekNrekAlerLkaklkekeleeekeeekkrrvkkekkkigtgs.sekiR 102
                   +++++++ + +r+sGaGGQ+VNktesa+rlth+ptg ++v++q++Rsq++Nr+kA+++L+akl+e+++e ++ee  k r +     ++++   +k R
  EEA19745.1 266 YYVNPQEVKSEKMRASGAGGQHVNKTESAIRLTHIPTG-LTVSMQDSRSQHANRKKAWQLLRAKLAERRREAREEEMVKLR-RGAMGGVAKMGrGDKVR 362
                 5689**********************************.8*************************8865555555444444.33444444444466*** PP

                 EEECGCTTEEEETT CS
        RF-1 103 tynkkpqsrvkdhr 116
                 tyn+ +qsr++dhr
  EEA19745.1 363 TYNF-SQSRCTDHR 375
                 ****.99******9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (421 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       803  (0.0447878); expected 358.6 (0.02)
Passed bias filter:                      545  (0.0303977); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.24s 00:00:00.73 Elapsed: 00:00:00.38
# Mc/sec: 3350.45
//
Query:       EEA19746.1  [L=298]
Description: mitochondrial tricarboxylate transporter (Ctp), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.7e-52  174.7   4.5    3.3e-23   81.4   0.2    4.0  4  Mito_carr  Mitochondrial carrier protein
  ------ inclusion threshold ------
       0.17   11.2   0.0       0.26   10.6   0.0    1.3  1  AgrB       Accessory gene regulator B


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4   0.0   2.3e-09     2e-05       4      38 ..      15      49 ..      12      56 .. 0.89
   2 !   12.2   0.0   1.5e-05      0.13      64      96 ..      65      97 ..      62      98 .. 0.93
   3 !   56.1   0.1     3e-19   2.7e-15       5      95 ..     103     193 ..      99     195 .. 0.91
   4 !   81.4   0.2   3.6e-27   3.3e-23       2      91 ..     200     286 ..     199     290 .. 0.94

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 2.3e-09
                HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC CS
   Mito_carr  4 svlkellaGglagavatlvttPldvvKtrlqtqkk 38
                s l++++aG++agav+  +t+P +++Ktr q++++
  EEA19746.1 15 SSLRSIIAGATAGAVEIAITYPAEFAKTRSQLNRR 49
                67899**************************9875 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 1.5e-05
                GGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCTT CS
   Mito_carr 64 lyrGllpnllrvapasalkfvlyetlkrlllkk 96
                 y G++  +++++ +++++fv+++++k ll+++
  EEA19746.1 65 WYAGCTTLMIGNSLKAGIRFVAFDKFKALLQDE 97
                69***************************9876 PP

  == domain 3  score: 56.1 bits;  conditional E-value: 3e-19
                 HHHHHHHHHHHHHH.HHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCT CS
   Mito_carr   5 vlkellaGglagav.atlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlllk 95 
                   ++++aG  ag + + l++tP++ +Kt+l  ++ks++ + ++ +l+  k i +e G+rg+++Gl+p+  r+a +sa++f++y t+k++++ 
  EEA19746.1 103 GPRTVIAGFGAGFTeSILAVTPFESIKTQLIDDRKSANPRMRG-FLQGSKIIAQERGIRGFFQGLVPTTARQAANSAVRFSSYTTIKQFVQG 193
                 56899*********555789****************9987655.*******************************************99875 PP

  == domain 4  score: 81.4 bits;  conditional E-value: 3.6e-27
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   2 elsvlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkr 91 
                 +l+vl+++++Gg+ag++++ vt+Pld+vKtr+q+ + ++++++    + ++ +i+k+eG++ l++G+lp+l r + + ++ f++ye++ +
  EEA19746.1 200 KLGVLSTFAIGGVAGIITVYVTQPLDTVKTRMQSLEARKNYKN---SIACFVQIVKNEGVLTLWSGALPRLARLIMSGGIVFTMYEKMMD 286
                 578999****************************999998877...788*************************************9976 PP

>> AgrB  Accessory gene regulator B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   2.9e-05      0.26      92     148 ..     187     248 ..     176     282 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 2.9e-05
        AgrB  92 lakllslsls....lllillliilliisliiilllaPvdtpnkpisskekkkklki.lsiiv 148
                 + ++++ +      l +++++ i  + ++i++++  P dt + +++s e +k++k  ++++v
  EEA19746.1 187 IKQFVQGYAApgekLGVLSTFAIGGVAGIITVYVTQPLDTVKTRMQSLEARKNYKNsIACFV 248
                 4455555555666667778888889999*********************9999999444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (298 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       421  (0.0234815); expected 358.6 (0.02)
Passed bias filter:                      389  (0.0216967); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.41u 0.23s 00:00:00.64 Elapsed: 00:00:00.37
# Mc/sec: 2424.84
//
Query:       EEA19747.1  [L=498]
Description: DEAD-box RNA helicase Dhh1/Vad1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.3e-43  146.6   0.1    8.9e-43  146.1   0.1    1.2  1  DEAD             DEAD/DEAH box helicase
    3.4e-28   98.2   1.0    6.2e-27   94.1   0.4    2.5  3  Helicase_C       Helicase conserved C-terminal domain
     0.0018   18.3   0.0     0.0033   17.4   0.0    1.4  1  ResIII           Type III restriction enzyme, res subunit
  ------ inclusion threshold ------
       0.15   11.4   0.0       0.35   10.2   0.0    1.5  1  CMS1             U3-containing 90S pre-ribosomal complex subu
       0.49   11.1  15.1          1   10.1  15.1    1.4  1  GRP              Glycine rich protein family


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  146.1   0.1   2.5e-46   8.9e-43       2     174 ..      70     233 ..      69     235 .. 0.96

  Alignments for each domain:
  == domain 1  score: 146.1 bits;  conditional E-value: 2.5e-46
                 HHHHHHHHHHHTTCEEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTCSE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   2 diQaeaiplilgggdvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngvdi 100
                 +iQ+e+ip +l+g+d+l++a+ G+GKT+af+ip l+++    ++t+++ali++PtreLa qt + +k+++k+++++v++++gg+   d++ +l+ +v+i
  EEA19747.1  70 PIQEETIPVALTGRDILARAKNGTGKTAAFIIPTLERIN--PKSTKTQALILVPTRELALQTSQVCKTLGKHLGINVMVTTGGTGLMDDIIRLNDTVHI 166
                 8*************************************5..699999**********************************************888*** PP

                 EEEEHHHHHHHHHCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD 101 vvgtpgrlddllstgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlpkdvk 174
                 +vgtpgr++dl s+g  +ls++ ++V+DEad+ll+ +f + i+++l+         +++rqv+++SAT+p  vk
  EEA19747.1 167 IVGTPGRVLDLASKGVADLSECPTFVMDEADKLLSPEFTPVIEQLLSFH-------PKDRQVMLFSATFPMIVK 233
                 ********************************************99999.......67899*******996655 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0      0.12   4.2e+02      12      49 ..     109     150 ..      98     163 .. 0.75
   2 ?   -2.6   0.0       1.9   6.8e+03       7      38 ..     209     238 ..     206     250 .. 0.69
   3 !   94.1   0.4   1.7e-30   6.2e-27       4     111 .]     271     377 ..     268     377 .. 0.89

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.12
                 HTTTTSEEEEEESSHH.HHHH...HHHHHHHTTSTEEEESTT CS
  Helicase_C  12 leeeggkilifvntid.rlek...vklllekkgikvavlhge 49 
                  ++ + ++li v+t++  l+    +k l ++ gi+v v +g 
  EEA19747.1 109 PKSTKTQALILVPTRElALQTsqvCKTLGKHLGINVMVTTGG 150
                 56778999********84433446777766669999988876 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.9
                 HHHHHHTTTTSEEEEEESSHHHHHHHHHHHHH CS
  Helicase_C   7 lellkleeeggkilifvntidrlekvklllek 38 
                  +ll+++ +++++++f+ t  ++  vk ++ k
  EEA19747.1 209 EQLLSFHPKDRQVMLFSATFPMI--VKSFKDK 238
                 45567778889999999998877..4666444 PP

  == domain 3  score: 94.1 bits;  conditional E-value: 1.7e-30
                 HHHHHHHHHTTTTSEEEEEESSHHHHHHHHHHHHHT...TSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSSHHH CS
  Helicase_C   4 eallellkleeeggkilifvntidrlekvklllekk...gikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprnvts 99 
                 ++l  l+ ++ + ++++if+n+++r+   +ll +k    g+++ + h+++ q +r++++++f++g ++ L+++d + rGidi+ vn+Vinfd+p+n ++
  EEA19747.1 271 HCLNTLF-SKLQINQSIIFCNSTNRV---ELLAKKItelGYSCFYSHARMLQHNRNRVFHDFRNGVCRNLVCSDLLTRGIDIQAVNVVINFDFPKNAET 365
                 4455555.889999************...55544445579*********************************************************** PP

                 HHHHHTTSSSTT CS
  Helicase_C 100 yiqriGRtgRag 111
                 y +riGR gR+g
  EEA19747.1 366 YLHRIGRSGRFG 377
                 **********86 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.0   9.2e-07    0.0033      27     169 ..      85     228 ..      61     230 .. 0.76

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 9.2e-07
                 EEEEESTTSTHHHHH.HHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG......GEEEESSS-B--.......-SEEEEEHHHHHHTH.... CS
      ResIII  27 glikmaTGtGKTlva.aklierllkkgkeekflflvprkslleqtleefkkflseayke..igkkvsgdkkkakekdstnkkilvttiqsldadseeee 122
                 +l  +  GtGKT    + + er+  k  + ++l+lvp+++l  qt +  k + +    +  +++  +g  +++  + +++ +i+v t  ++        
  EEA19747.1  85 ILARAKNGTGKTAAFiIPTLERINPKSTKTQALILVPTRELALQTSQVCKTLGKHLGINvmVTTGGTGLMDDI-IRLNDTVHIIVGTPGRVLDLA---- 178
                 6677788******99899999*****9999****************888777665543344444455555555.567899999999999888777.... PP

                 ....HHHTTT-SEEEEETGGGTTS.TTTHHHHHT-.....--SEEEEEESS- CS
      ResIII 123 eeseellrdrfdviiiDEaHrlgakkswreilekf.....keavllglTATp 169
                   +  ++ ++ + +++DEa +l +  +++ ++e++     k+  ++ ++AT+
  EEA19747.1 179 -SKGVADLSECPTFVMDEADKLLS-PEFTPVIEQLlsfhpKDRQVMLFSATF 228
                 .67888888888999999999998.655555444434444556677788887 PP

>> CMS1  U3-containing 90S pre-ribosomal complex subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   9.7e-05      0.35     145     209 ..     121     195 ..     114     198 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 9.7e-05
        CMS1 145 alkklqtkdskvakLFakhikleesvty.........lk.ksrigiavGtpgRildLleeeslsvdeLkrivlDa 209
                 ++++l  + s+v k  +kh+ ++  vt+         ++ +  + i vGtpgR+ldL  +++  ++e    v+D 
  EEA19747.1 121 PTRELALQTSQVCKTLGKHLGINVMVTTggtglmddiIRlNDTVHIIVGTPGRVLDLASKGVADLSECPTFVMDE 195
                 5677777788888888999888888876333322222231346899****************9999999999885 PP

>> GRP  Glycine rich protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1  15.1   0.00028         1      39      78 ..     437     490 ..     428     495 .. 0.60

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00028
         GRP  39 evkdekyggg..gkh............ggGgygggggggngGGGykgggGgygg 78 
                 e+++ ++ g+  g+h            g+Ggy g gg+g+  GGy++ +G+ gg
  EEA19747.1 437 ETQQREQQGYrqGNHhpggrynnnagrGRGGYRGRGGQGQRRGGYQNPHGHDGG 490
                 233333322200333455555567888888888888888888888888886655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (498 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       535  (0.0298399); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.41
# Mc/sec: 3660.46
//
Query:       EEA19748.1  [L=1143]
Description: DNA repair protein Rad18, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-20   73.7  10.6      1e-19   70.9  10.6    2.4  1  SMC_N         RecF/RecN/SMC N terminal domain
      4e-17   63.4   6.6      4e-17   63.4   6.6    5.5  3  AAA_23        AAA domain
    2.3e-11   44.0  12.9    2.3e-11   44.0  12.9    3.7  2  AAA_15        AAA ATPase domain
    3.5e-07   30.3  14.3    3.2e-06   27.2   1.8    4.2  4  AAA_21        AAA domain, putative AbiEii toxin, Type IV TA s
    9.5e-06   25.9   0.7    0.00013   22.2   0.0    2.8  2  SMC_hinge     SMC proteins Flexible Hinge Domain
     0.0007   19.3   0.0     0.0016   18.1   0.0    1.6  1  AAA_29        P-loop containing region of AAA domain
  ------ inclusion threshold ------
      0.073   13.6   0.1      0.073   13.6   0.1    5.9  3  ABC_tran      ABC transporter
       0.16   12.4   1.0         22    5.5   0.0    3.7  3  DUF5104       Domain of unknown function (DUF5104)
        0.2   12.1   9.8        2.4    8.6   0.1    3.7  3  Caskin-tail   C-terminal region of Caskin
        3.5    6.4  86.1      0.029   13.3  12.8    5.7  6  Spc7          Spc7 kinetochore protein


Domain annotation for each model (and alignments):
>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.9  10.6   5.8e-23     1e-19       2     196 ..     102    1110 ..     101    1118 .. 0.96

  Alignments for each domain:
  == domain 1  score: 70.9 bits;  conditional E-value: 5.8e-23
                  EEEEEEESETTEECEEEEEETTSSEEEEEESTTSSHHHHHHHHHHHCTT.TTTTTTCHCCCCCC--BTTCSSTTEEEEEEEEEETTEE..SSSSS.S CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxx.x RF
       SMC_N    2 lkrleienFksyagktvilpfsksftaivGpNGSGKsnlldAilFvLGersakklrseklsdlihkskekasvkkaeveitfdnedkk..lkiek.e 95  
                  ++r+   nF     ++ ++++ + +++ivG+NGSGKs +l A+  +LG +++ + r ++l++ i++       ++a++ + ++n+++   ++ e  +
  EEA19748.1  102 IERVDCFNFMCH--EHFSVDLGPLINFIVGKNGSGKSAILTALTLCLGAKASVTNRGQSLKSFIKE-----GKESATIIVRIKNQGDGayMPNEYgK 191 
                  566667777766..79999**********************************************8.....55667777777777776333333314 PP

                  CEEEEEEEETTSEEEEEETTEE.....E-HHHHHHHHHCTT-STT.................................................... CS
                  xxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxx.................................................... RF
       SMC_N   96 evsisrrvkrkgeseykingke.....vtkkevsellesagiske.................................................... 135 
                  ++ ++r+ +++g+s +ki+ +       +k ++  +    +++++                                                    
  EEA19748.1  192 SIIVERSFSKSGTSGFKIKSEAgkiisTKKGDLDAITDYFNLQIDnpmnvlsqdmarqflsssspaekykffvkgvqleqldndyrviegyidqmke 288 
                  5999**************77651111134578888888888888899************************************************** PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19748.1  289 rlevqredlkvlrgnkekaqrrlelsdqrntlrqrirnlraqmawaqvenqerirdriqeeiakldgqiasaesataifdrkyeeaereletatell 385 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19748.1  386 nstkealskaqdesqvlkdanaqdmaehhdikaeqrridqsvkslnsaiealkqqiadenkrladiaggdiarrqeelahrraeadeaeeklnqhqg 482 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19748.1  483 gfkdlqdavrdadqivkqvtapiqkqkreidqaetllrslskdrgqalsgfsekmpqllnaiareksfnqrpvgpvgnhvrlkkpewsavieqslnn 579 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19748.1  580 tlnsfivtskkdmnilmqimqrlncvmpiligsngaidttanepdkrfdtilsvleidedivrrqliinhaieqivlienveeaskilfeggrvrnv 676 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19748.1  677 rrclcidardrrrgvtlsygrtgepsqapiapyvgrprmksdidsqikfqqdhiqalkrelnelqskhtasqaelqrrmlaltehktkenelrieqq 773 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19748.1  774 rlsdaadaledalekdqvvdgkletlqntlkeregeqklavnslddakaaldsmrekllkqrkaisakdaeikplednvaiaeserlkvetqrravl 870 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA19748.1  871 neknhayervtdlkqerdarignkeemntrvtnyieqaslvsprvpvdegetadsldkkleklskdldrydqqmgatreeiagdllnaskavkaaet 967 
                  ************************************************************************************************* PP

                  ...............................................................................CS-HHHHHHHHHHHHHHH CS
                  ...............................................................................xxxxxxxxxxxxxxxxxx RF
       SMC_N  136 ...............................................................................lLSgGektLvalaLlfAi 153 
                                                                                                 +LSgGek+ + + Ll+++
  EEA19748.1  968 syqsterlekelkrsinyrrerwkvfrahissrakaqftyllsersfrgrllmdheaklldlqvepditknnaggrgtkTLSGGEKSFSQICLLLSL 1064
                  ************************************************************************************************* PP

                  HCCS--SEEEECTTTTTS-HHHHHHHHHHHH...HHCTTSEEEEE- CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxx RF
       SMC_N  154 qkvkpaplyllDeidaaLDeknvkkvaellk...eksknaQfivis 196 
                   ++  +p+ +lDe+d  +D+ n+k   ++l    ++s   Qfi i+
  EEA19748.1 1065 WEAMGSPIRCLDEFDVYMDHINRKSSIDMLMlaaRRSIGRQFILIT 1110
                  *************************999987433444458999998 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.4   6.6   2.2e-20     4e-17       6     175 ..     109     330 ..     104     358 .. 0.55
   2 ?  -18.8  33.3        10   1.8e+04      70     198 ..     304     447 ..     302     526 .. 0.62
   3 ?  -20.5  32.1        10   1.8e+04     133     183 ..     757     807 ..     668     992 .. 0.60

  Alignments for each domain:
  == domain 1  score: 63.4 bits;  conditional E-value: 2.2e-20
      AAA_23   6 nfrsfrdqeidFskgltlItGpNGaGKTTildAiklaLygetprlsrksgrgfeksdveiesegkvkayveltfe.nkdgry.......trsiererel 96 
                 nf++++++++d+++ ++ I+G+NG+GK++il A++l+L+ +++ ++r+    + ks ++   egk +a + ++++   dg y         ++er++++
  EEA19748.1 109 NFMCHEHFSVDLGPLINFIVGKNGSGKSAILTALTLCLGAKASVTNRG---QSLKSFIK---EGKESATIIVRIKnQGDGAYmpneygkSIIVERSFSK 201
                 9***************************************98866663...33455555...4444444333344044555599999888999999999 PP

      AAA_23  97 skkkgkttkkaklellei.deleqfisellgskki...........ilnlilflgqer......................................fee 145
                 s ++g ++k ++++++++ +   + i+++++ + +           +          +                                      +  
  EEA19748.1 202 SGTSGFKIKSEAGKIISTkKGDLDAITDYFNLQIDnpmnvlsqdmaR----------QflsssspaekykffvkgvqleqldndyrviegyidqmkE-- 288
                 99999999999999999974445666665555433323333333331..........1222222333344444443333333333333333322110.. PP

      AAA_23 146 fel..............kdkkerleelekeleeledekkllekl 175
                   +              k+k +r  el+++ ++l ++++ l+++
  EEA19748.1 289 --RlevqredlkvlrgnKEKAQRRLELSDQRNTLRQRIRNLRAQ 330
                 ..111122222222222222224444444444444444444444 PP

  == domain 2  score: -18.8 bits;  conditional E-value: 10
      AAA_23  70 kvkayveltfenkdgrytrsiererelskkkgkttkkaklelleideleqfisellgskkiilnlilflgqerfeefelkdkkerleelekeleelede 168
                 k ka+ +l++++++++    +++++ + + ++   + ++ e ++++ +e++ +   ++  +++   +f  + +++e el++  e l++ +++l +++de
  EEA19748.1 304 KEKAQRRLELSDQRNT----LRQRIRNLRAQMAWAQVENQERIRDRIQEEIAKLDGQIASAESATAIFDRKYEEAERELETATELLNSTKEALSKAQDE 398
                 5566677777777774....5444444444445555555555555555555555555555555555555555555556666666666666666666666 PP

      AAA_23 169 kkllekl...................eqekekekeleeleeeleeilke 198
                  + l++                    +  k+ + ++e+l++++ + +k 
  EEA19748.1 399 SQVLKDAnaqdmaehhdikaeqrridQSVKSLNSAIEALKQQIADENKR 447
                 6666666666666666555444444434444444555555555554444 PP

  == domain 3  score: -20.5 bits;  conditional E-value: 10
      AAA_23 133 nlilflgqerfeefelkdkkerleelekeleeledekkllekleqekekek 183
                  l   + +e++ ++e+++ +++ ++le++le+ + ++ +le+l++ +++++
  EEA19748.1 757 ALTEHKTKENELRIEQQRLSDAADALEDALEKDQVVDGKLETLQNTLKERE 807
                 111111111122222222222222222222222222223333322222222 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.0  12.9   1.3e-14   2.3e-11       3     273 ..     102     507 ..     101     543 .. 0.76
   2 ?  -10.1  16.3        10   1.8e+04     154     235 ..     760     859 ..     713    1006 .. 0.49

  Alignments for each domain:
  == domain 1  score: 44.0 bits;  conditional E-value: 1.3e-14
      AAA_15   3 IkkikikNFRslkdveidlseeltvliGkNnsGKSsilealdlFlnnkekknkkvikiekedleifeniseskdikIdvef.................. 83 
                 I+++   NF +++++++dl + +++++GkN+sGKS il al l l  k     +v++  ++  +  ++ +es +i ++++                   
  EEA19748.1 102 IERVDCFNFMCHEHFSVDLGPLINFIVGKNGSGKSAILTALTLCLGAK----ASVTNRGQSLKSFIKEGKESATIIVRIKNqgdgaympneygksiive 196
                 6777778***************************************99....56667777777777777777777777777777777777777777777 PP

      AAA_15  84 ...........................................................................................aek..eka 89 
                                                                                                            +     ++
  EEA19748.1 197 rsfsksgtsgfkikseagkiistkkgdldaitdyfnlqidnpmnvlsqdmarqflsssspaekykffvkgvqleqldndyrviegyidqmkE-RleVQR 294
                 777999999999999999999999999999999999999***************************************99999999988641.254556 PP

      AAA_15  90 keyektlkskekkkadlllkkkesdlkktikdkklklkknelsdekisvekkks.......kkelpkekeeklekekeelkidkedlkklikkleeslk 181
                 ++  ++  +kek ++ l+l + ++ l ++i++   +  + ++ ++    + +++                 ++e+  + ++ + e++++ +++ +e l+
  EEA19748.1 295 EDLKVLRGNKEKAQRRLELSDQRNTLRQRIRNLRAQMAWAQVENQERIRDRIQEeiakldgQ-------IASAESATAIFDRKYEEAERELETATELLN 386
                 66666777888888888999999999999999999999988888888888888845555553.......444444444444444444444444444444 PP

      AAA_15 182 kee............elknvlksaiiklllisakRnvsdedsekkssllgklkekileealqekl.....................eeelteklkeiqe 247
                 + +            +++ + ++ ++  ++  ++R ++++ +   +s++++lk++i +e  +++l                      +e +ekl++ q 
  EEA19748.1 387 STKealskaqdesqvLKDANAQDMAEHHDIKAEQRRIDQSVKSL-NSAIEALKQQIADE--NKRLadiaggdiarrqeelahrraeADEAEEKLNQHQG 482
                 44444444558898888999999999999999999999988777.9***********98..466779*****888777777777776677777777777 PP

      AAA_15 248 klkeidkklaeelkkilkkkidkikk 273
                  +k++++ +  ++ +i+k+    i+k
  EEA19748.1 483 GFKDLQDAV-RDADQIVKQVTAPIQK 507
                 777777776.4444444444444332 PP

  == domain 2  score: -10.1 bits;  conditional E-value: 10
      AAA_15 154 klekekeelkidkedlkklikkleeslkkeeelknvlksaiiklllisakRnvsdedsekkssllgklkekileealqekl.................. 234
                 +++++++el i+++ l +  + le  l+k+++++ +l+ ++ +l+  + +++   +  +  + +l++  ek+l++ +   +                  
  EEA19748.1 760 EHKTKENELRIEQQRLSDAADALEDALEKDQVVDGKLETLQNTLKEREGEQKLAVNSLDDAKAALDSMREKLLKQRK---Aisakdaeikplednvaia 855
                 34444455555555555555555555555543333333333333333333333333333333333333333333211...1111222222222222222 PP

      AAA_15 235 ...e 235
                    +
  EEA19748.1 856 eseR 859
                 2221 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.2   1.8   1.8e-09   3.2e-06       1     108 [.     124     237 ..     124     378 .. 0.80
   2 ?   -1.0   0.3      0.69   1.2e+03     120     218 ..     762     866 ..     734     890 .. 0.70
   3 ?    0.2   0.1      0.29   5.1e+02      84     142 ..     959    1017 ..     914    1024 .. 0.77
   4 !    8.6   0.0   0.00081       1.5     237     296 ..    1048    1110 ..    1046    1111 .. 0.87

  Alignments for each domain:
  == domain 1  score: 27.2 bits;  conditional E-value: 1.8e-09
      AAA_21   1 lnvliGpNgsGKSnLLdaldllarl.drdvegltdelsggggirkipslldlydpeipfefeieeflsqgvryryglrlersqv.....eeklssvetl 93 
                 +n+++G+NgsGKS +L al l  ++ ++  +++++ +s +++ ++ +  + ++   +++++  +e +++ ++ r + + + s++     + k++s +++
  EEA19748.1 124 INFIVGKNGSGKSAILTALTLCLGAkASVTNRGQSLKSFIKEGKESATIIVRIKNQGDGAYMPNEYGKSIIVERSFSKSGTSGFkikseAGKIISTKKG 222
                 79***********************99999999999999999999999999*********************************888886666666666 PP

      AAA_21  94 lesgllldkrsleee 108
                  ++ ++++    ++ 
  EEA19748.1 223 DLDAITDYFNLQIDN 237
                 666666555544444 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.69
      AAA_21 120 ggvsvfslkelsvsepndlqfgkaltditsrawsllllldglrke......rigllnifadyfgfakekrllqrlvrslklveielsdlgegeeliasv 212
                 +++ ++ ++e  + ++ ++  ++al ++     +l+ l++ l ++      + + l+++++ +  ++ek l qr   s k++ei++   ++++ ++++ 
  EEA19748.1 762 KTKENELRIEQQRLSDAADALEDALEKDQVVDGKLETLQNTLKERegeqklAVNSLDDAKAALDSMREKLLKQRKAISAKDAEIKPLEDNVAIAESERL 860
                 444455555555555555555555555555555555555555555666777888999999999999999999999999999999998888877777777 PP

      AAA_21 213 derlre 218
                 ++  ++
  EEA19748.1 861 KVETQR 866
                 766666 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.29
      AAA_21   84 eeklssvetllesgllldkrsleeedvfnpeargirggvsvfslkelsvsepndlqfgk 142 
                  +  +++ et  +s++ l k+ +++++    +++ +r+ +s++  +++++  +++ ++g+
  EEA19748.1  959 SKAVKAAETSYQSTERLEKELKRSINYRRERWKVFRAHISSRAKAQFTYLLSERSFRGR 1017
                  5566778889999999999999999999999*999999999999999999888887765 PP

  == domain 4  score: 8.6 bits;  conditional E-value: 0.00081
      AAA_21  237 lSdGtkrll..alltallralkkgsllliDEpEngLHPkllrrllellkelsr..ngaQviltT 296 
                  lS G k++   +ll++l++a ++ ++ ++DE++  +++   ++ +++l +++r   g Q+il T
  EEA19748.1 1048 LSGGEKSFSqiCLLLSLWEAMGS-PIRCLDEFDVYMDHINRKSSIDMLMLAARrsIGRQFILIT 1110
                  68899999777************.**************99999999996666656688998887 PP

>> SMC_hinge  SMC proteins Flexible Hinge Domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.2   0.0   7.3e-08   0.00013       4     116 ..     554     666 ..     551     667 .. 0.83
   2 ?    0.6   0.1      0.37   6.6e+02      31      61 ..     810     840 ..     807     878 .. 0.72

  Alignments for each domain:
  == domain 1  score: 22.2 bits;  conditional E-value: 7.3e-08
   SMC_hinge   4 vlGrladlievd.egyekAveaalgnrlqalvvedeetakkiieflkkknagratflpldrikqknkadgandknsgavplidlvevdde.lrkal..r 98 
                  +G++++ ++++ +++ + +e+ l n l++++v ++++   +++ +++     + +l  ++   +  a+++++   +    ++++e d+  +r+ l  +
  EEA19748.1 554 PVGPVGNHVRLKkPEWSAVIEQSLNNTLNSFIVTSKKDMNILMQIMQRL-NCVMPILIGSNGAIDTTANEPDK---RFDTILSVLEIDEDiVRRQLiiN 648
                 589*************************************999999999.56666666655333333333333...899***********988866569 PP

   SMC_hinge  99 yllgdtlvvdsldeAeel 116
                 +++ ++++ ++++eA ++
  EEA19748.1 649 HAIEQIVLIENVEEASKI 666
                 ***************998 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.37
   SMC_hinge  31 qalvvedeetakkiieflkkk.nagratflpl 61 
                 q l v + ++ak++++ +++k  + r ++ ++
  EEA19748.1 810 QKLAVNSLDDAKAALDSMREKlLKQRKAI-SA 840
                 568999*********99999943444333.33 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   9.1e-07    0.0016      16      50 ..     115     150 ..     102     155 .. 0.74

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 9.1e-07
      AAA_29  16 tieidlkg.atlltGpsGsGKSTllDAiqalLvpak 50 
                  +++dl   + +++G++GsGKS++l A++  L ++ 
  EEA19748.1 115 HFSVDLGPlINFIVGKNGSGKSAILTALTLCLGAKA 150
                 455555556899*************99988776654 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   4.1e-05     0.073      15      35 ..     126     146 ..     115     189 .. 0.75
   2 ?   -9.9  13.1        10   1.8e+04      58      80 ..     308     380 ..     275     549 .. 0.60
   3 ?   -2.1   8.7       2.8   5.1e+03      58     125 ..     980    1066 ..     714    1078 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 4.1e-05
                 EEEESTTSSHHHHHHHHTTSS CS
                 xxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  15 aivGenGaGKStLlkllagll 35 
                  ivG+nG+GKS +l +l+  l
  EEA19748.1 126 FIVGKNGSGKSAILTALTLCL 146
                 69*************998655 PP

  == domain 2  score: -9.9 bits;  conditional E-value: 10
                 CHCEEEE-SS--S-TTSBHHHH..................................................H CS
                 xxxxxxxxxxxxxxxxxxxxxx..................................................x RF
    ABC_tran  58 rkeigvlpqepqlfpeltvren..................................................e 80 
                 +++++   q ++l +++++ +                                                   +
  EEA19748.1 308 QRRLELSDQRNTLRQRIRNLRAqmawaqvenqerirdriqeeiakldgqiasaesataifdrkyeeaereleT 380
                 3333333344333333332222233333332222222233335544444444444444333333322222220 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 2.8
                  CHCEEEE-SS--S-TTSBHHHH..................HHHTCHHHHHHHSTTGGTTCBGESTTSGGS-HHHHH..HHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxx..................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxx RF
    ABC_tran   58 rkeigvlpqepqlfpeltvren..................esdeeiekalsklglkelkdtvvksspssLSgGqkq..rvalarallk 125 
                  +++i +  +  ++f+ + + ++                   +d e++ +  +++ + +k++  ++++++LSgG+k+   ++l  +l++
  EEA19748.1  980 KRSINYRRERWKVFRAH-ISSRakaqftyllsersfrgrlLMDHEAKLLDLQVEPDITKNNAGGRGTKTLSGGEKSfsQICLLLSLWE 1066
                  23333333332222222.2222333344433333333334333333333333333334455555556999999998445555555554 PP

>> DUF5104  Domain of unknown function (DUF5104)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.0     0.012        22      21      64 ..     334     377 ..     321     392 .. 0.78
   2 ?   -1.7   0.0       2.2   3.9e+03      24      55 ..     436     467 ..     419     483 .. 0.74
   3 ?    2.7   0.1      0.09   1.6e+02      23      72 ..     934     983 ..     923    1000 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.012
     DUF5104  21 kalkesddldeeidelidfykGdivsyeeasssseessesgktk 64 
                  ++++++ + + i+e i +++G+i s e+a++  + ++e+ +++
  EEA19748.1 334 AQVENQERIRDRIQEEIAKLDGQIASAESATAIFDRKYEEAERE 377
                 4568999*************************999666655544 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 2.2
     DUF5104  24 kesddldeeidelidfykGdivsyeeasssse 55 
                 + ++++ +e ++l d   Gdi + +e+ ++  
  EEA19748.1 436 ALKQQIADENKRLADIAGGDIARRQEELAHRR 467
                 45778889999999999999999999888877 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.09
     DUF5104  23 lkesddldeeidelidfykGdivsyeeasssseessesgktktktlsaiy 72 
                 +k+ d  d+++ ++ + + Gd+++  +a++  e+s++s ++ +k+l+  +
  EEA19748.1 934 SKDLDRYDQQMGATREEIAGDLLNASKAVKAAETSYQSTERLEKELKRSI 983
                 466677899************************99999888886666554 PP

>> Caskin-tail  C-terminal region of Caskin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.1    0.0013       2.4       1      27 [.     420     446 ..     420     454 .. 0.92
   2 ?    5.3   3.2     0.015        27       1      52 [.     772     826 ..     772     832 .. 0.87
   3 ?   -2.7   0.0       4.5   8.1e+03       6      33 ..     921     946 ..     920     957 .. 0.70

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0013
  Caskin-tail   1 qqrleqtsasLaaaLkavEkkikqees 27 
                  q+r++q+  sL++a++a  ++i++e++
   EEA19748.1 420 QRRIDQSVKSLNSAIEALKQQIADENK 446
                  89*********************9987 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.015
  Caskin-tail   1 qqrleqtsasLaaaL...kavEkkikqeesessssaaevksaknILdDIgnMFDd 52 
                  qqrl ++  +L+ aL   ++v+ k+++ +++ +    e+k a+n LdD     D 
   EEA19748.1 772 QQRLSDAADALEDALekdQVVDGKLETLQNTLKEREGEQKLAVNSLDDAKAALDS 826
                  8**************66669******99999998999***********8776665 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 4.5
  Caskin-tail   6 qtsasLaaaLkavEkkikqeesessssa 33 
                  +t  sL++ L+   k +   +++    a
   EEA19748.1 921 ETADSLDKKLEKLSKDLDRYDQQMG--A 946
                  6888999999998888888888766..3 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6  18.4   0.00042      0.76     136     269 ..     278     411 ..     275     416 .. 0.85
   2 ?   13.3  12.8   1.6e-05     0.029     154     259 ..     412     521 ..     404     542 .. 0.87
   3 ?   -1.4   0.0      0.46   8.2e+02     131     181 ..     568     618 ..     568     631 .. 0.82
   4 ?    1.7   9.2     0.052        93     196     262 ..     725     791 ..     714     795 .. 0.77
   5 ?    2.9  18.0     0.023        42     147     261 ..     771     884 ..     765     897 .. 0.67
   6 ?   -0.3   5.2      0.21   3.8e+02     170     257 ..     924     986 ..     879    1015 .. 0.56

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00042
        Spc7 136 llegLkegleenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLe.elreelaelkaeieekkkelaelqeqleele 233
                  +eg  ++++e+le  +ed ++L  ++e++++ l el+ ++++l++++++l+++ +  +  ++e+++  ++ee+a+l+ +i++ +  +a   ++ ee e
  EEA19748.1 278 VIEGYIDQMKERLEVQREDLKVLRGNKEKAQRRL-ELSDQRNTLRQRIRNLRAQMAWAQVENQERIRdRIQEEIAKLDGQIASAESATAIFDRKYEEAE 375
                 67888999**********************9976.699999************7776666668888635899999999999999999999999999999 PP

        Spc7 234 ekieelkeqkseleeeiaeaervleeckgwsesevs 269
                  ++e+++e  ++++e++++a++  +  k+ ++++  
  EEA19748.1 376 RELETATELLNSTKEALSKAQDESQVLKDANAQDMA 411
                 999999999999999999999888888888877765 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 1.6e-05
        Spc7 154 dkelLekqeeeldellpeleeekaeleeeleklqeaaeeles....idkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkselee 248
                 +   +++++  +d+ +++l++  ++l++++++++++ ++++       +eeL+  r e +e+++++++++   ++lq+ + + ++ ++++++ +++ + 
  EEA19748.1 412 EHHDIKAEQRRIDQSVKSLNSAIEALKQQIADENKRLADIAGgdiaRRQEELAHRRAEADEAEEKLNQHQGGFKDLQDAVRDADQIVKQVTAPIQKQKR 510
                 556789999999999999***************9999999886654559************************************************** PP

        Spc7 249 eiaeaervlee 259
                 ei +ae +l+ 
  EEA19748.1 511 EIDQAETLLRS 521
                 *****998765 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.46
        Spc7 131 eWRmqllegLkegleenlegleedkelLekqeeeldellpeleeekaelee 181
                 eW     ++L ++l++ + + ++d + L++ ++ l+ ++p l     ++  
  EEA19748.1 568 EWSAVIEQSLNNTLNSFIVTSKKDMNILMQIMQRLNCVMPILIGSNGAIDT 618
                 6777778899999999999****************9999988766666655 PP

  == domain 4  score: 1.7 bits;  conditional E-value: 0.052
        Spc7 196 idkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaervleeckg 262
                  +++ +++l++el+el+++  + ++el+++   l+e ++k +el+ + ++l ++  + e+ le+ + 
  EEA19748.1 725 FQQDHIQALKRELNELQSKHTASQAELQRRMLALTEHKTKENELRIEQQRLSDAADALEDALEKDQV 791
                 5678888888888888888888888888888888888888888888888888888888888887765 PP

  == domain 5  score: 2.9 bits;  conditional E-value: 0.023
        Spc7 147 nlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkse 245
                 + + l + ++ Le+  e+ + +  +le+ +++l+e+  +++ a+++l++  k+ L ++re+l ++ + i++k +e++ l+++++  e++  ++++q++ 
  EEA19748.1 771 EQQRLSDAADALEDALEKDQVVDGKLETLQNTLKEREGEQKLAVNSLDD-AKAALDSMREKLLKQRKAISAKDAEIKPLEDNVAIAESERLKVETQRRA 868
                 4455555566666666666666666666666666555555555554443.5888999999999999999999999999999999888888888888888 PP

        Spc7 246 leeeiaeaervleeck 261
                 + +e ++a + +   k
  EEA19748.1 869 VLNEKNHAYERVTDLK 884
                 8777776654444433 PP

  == domain 6  score: -0.3 bits;  conditional E-value: 0.21
        Spc7 170 peleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaervl 257
                 ++l                          ++Le+l ++l++ ++++ + ++e+a    +  +  ++ e+  ++ ++le+e++++ +++
  EEA19748.1 924 DSL-------------------------DKKLEKLSKDLDRYDQQMGATREEIAGDLLNASKAVKAAETSYQSTERLEKELKRSINYR 986
                 333.........................344555555555555555544444443333333333333333333333333333333322 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1143 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2229  (0.124324); expected 358.6 (0.02)
Passed bias filter:                      583  (0.0325172); expected 358.6 (0.02)
Passed Vit filter:                       128  (0.00713927); expected 17.9 (0.001)
Passed Fwd filter:                        71  (0.00396006); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 1.95u 0.36s 00:00:02.31 Elapsed: 00:00:00.62
# Mc/sec: 5558.61
//
Query:       EEA19749.1  [L=477]
Description: glutamate carboxypeptidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.5e-33  114.2   0.0    8.3e-33  113.8   0.0    1.1  1  Peptidase_M20  Peptidase family M20/M25/M40
    2.3e-13   50.0   0.0    4.1e-13   49.2   0.0    1.4  1  M20_dimer      Peptidase dimerisation domain
  ------ inclusion threshold ------
      0.038   13.7   0.0      0.085   12.5   0.0    1.6  1  Peptidase_M28  Peptidase family M28


Domain annotation for each model (and alignments):
>> Peptidase_M20  Peptidase family M20/M25/M40
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.8   0.0   1.4e-36   8.3e-33       1     205 [.      94     467 ..      94     469 .. 0.88

  Alignments for each domain:
  == domain 1  score: 113.8 bits;  conditional E-value: 1.4e-36
                    EEEEES-BSSTTCGGGSSS.TTSEE.ETTTEEESTTTTTTHHHHHHHHHHHHHHHHHTTT-SSEEEEEEESTTSSTTTHHHHHHHHHH.TTTCESE CS
                    xxxxxxxxxxxxxxxxxxx.xxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxx RF
  Peptidase_M20   1 llgsHlDvVpeeetdgwtt.pfslt.eedGklyGrGaddmkggvlaalealralkdegikpkgtivllfqpdEEggrgGakallegle.erekvda 93 
                    l+++H+Dv+p+ ++dgw t pf+lt +e++++yGrG++d+kg vl++l +++a+k++gi+ + ++   f++ EE g++G   ++e +e +++  d 
     EEA19749.1  94 LVYGHYDVQPALKEDGWATePFELTiDEKDRMYGRGSTDDKGPVLGWLNVIEAHKKAGIEFPVNLLCCFEGMEEYGSEGLDDFIE-AEaKAFFKDT 188
                    689*******777789*********97779********************************************888999*****.3323333333 PP

                    EEEEEEESSSBTCHSTETEEEE.......................................................................... CS
                    xxxxxxxxxxxxxxxxxxxxxx.......................................................................... RF
  Peptidase_M20  94 vfelhieepgileagklaigvv.......................................................................... 115
                       + i++  +l  +k  + ++                                                                          
     EEA19749.1 189 DA-VCISDNYWLGTEK--PCLTyglrgcnyyavtisgpgqdlhsgvfggsahepmtdlvtvfsklvdsqgsiqipglmdlvapvtaeeeklypnis 281
                    22.4455444444333..4444677788888888888888888888899*********************************************** PP

                    ...........................................................................................EEEEE CS
                    ...........................................................................................xxxxx RF
  Peptidase_M20 116 ...........................................................................................kveve 120
                                                                                                               + +v+
     EEA19749.1 282 ysmddlheslgsktsihatkertlmarwrypslsihgiegafsapgaktvipakvigkfsirtvpnmesedvtrlvkdyinsefaklgsknTLDVS 377
                    ******************************************************************************************779*** PP

                    EEEEESHEEEC.CHHHHHHHHHHHHHHHTSCEEEEEES...SSBHTHHHHTTTEEEEE..EESSGGCTTSTTTEEEHHHHHHHHHHHHHHH CS
                    xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_M20 121 lleggapvtln.dsplvkalaeaaeelfgekvelivsg...pggtdarffagiptvmi..fgpgsglaHspnEyvdledlekgikvlarll 205
                    l ++g+ ++++  +  + a+++a++++fg++++++  g   p +  +    g  +v++  +g + + aHs nE++d +++ +g+k+l ++l
     EEA19749.1 378 LMHDGKWWVASpKHWNFTAASKAVQQVFGVEPDMTREGgsiPVTLTFEQATGK-NVLLlpMGSSTDAAHSINEKLDKSNYIQGTKLLGAYL 467
                    99*********55555*************998888555477777777777777.66443888666*********************99887 PP

>> M20_dimer  Peptidase dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.2   0.0   6.8e-17   4.1e-13       2     106 ..     209     366 ..     208     368 .. 0.95

  Alignments for each domain:
  == domain 1  score: 49.2 bits;  conditional E-value: 6.8e-17
                 EB-EEEEEEEE..EE-B-EEGG.-TTTTB-HHHHHHHHHHCSCTTEEC................................................... CS
   M20_dimer   2 ghkGlaggkit..vkgkagHsg.apgagaNAieklarllaeledeegdia..............................................eer 51 
                 g++G   + +t    g+++Hsg ++g +  +++ l+ + ++l d +g+i+                                              +  
  EEA19749.1 209 GLRGCNYYAVTisGPGQDLHSGvFGGSAHEPMTDLVTVFSKLVDSQGSIQipglmdlvapvtaeeeklypnisysmddlheslgsktsihatkertLMA 307
                 56666666666559************************************************************************************* PP

                 TCCTCCCCCEECCE-C....CCCEESSEEEEEEEEEHHHHHHHHHHHHHHHHHHTSCCS CS
   M20_dimer  52 slprttlnvtgiegGs....aknvipdeaeakidiRllpgedpeevleeieeilekeap 106
                 ++++++l++ gieg +    ak+vip+++  k++iR++p+++ e+v   +++++++e +
  EEA19749.1 308 RWRYPSLSIHGIEGAFsapgAKTVIPAKVIGKFSIRTVPNMESEDVTRLVKDYINSEFA 366
                 ******************************************************99865 PP

>> Peptidase_M28  Peptidase family M28
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   1.4e-05     0.085       2      93 ..      80     190 ..      79     218 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.4e-05
                    EEEEESTTCE.SEEEEEEEE--B-TTT...............TCC..T---TTTTHHHHHHHHHHHHHCHHGGCCSSEEEEEEEESSCSGSSHHHH CS
  Peptidase_M28   2 viatlegkat.devlllgAHyDsvgvg...............rgp..ifvGAdDnAsgvaalLelarvlaasgsrpkrgvrflffdaEEagllGSk 79 
                    via++ g+++ ++++l+ +HyD  +                 +++     G +D+  +v   L+++++ ++ g +   ++   f + EE+g  G +
     EEA19749.1  80 VIARY-GNDPnKRTILVYGHYDVQPALkedgwatepfeltidEKDrmYGRGSTDDKGPVLGWLNVIEAHKKAGIEFPVNLLCCFEGMEEYGSEGLD 174
                    78888.5555478**********9988999***99999999733355668*********************99999***************99999 PP

                    HHHH..HHCCCTTEEE CS
  Peptidase_M28  80 afak..akpelkkiaa 93 
                     f++  ak   k+++a
     EEA19749.1 175 DFIEaeAKAFFKDTDA 190
                    9997533335555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (477 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       324  (0.0180713); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 3346.79
//
Query:       EEA19750.1  [L=149]
Description: 60S ribosomal protein L20, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-34  119.7   4.4    1.6e-34  119.5   4.4    1.1  1  MRP-L20   Mitochondrial ribosomal protein subunit L20
  ------ inclusion threshold ------
      0.055   13.5   0.9      0.076   13.0   0.9    1.2  1  Neugrin   Neugrin


Domain annotation for each model (and alignments):
>> MRP-L20  Mitochondrial ribosomal protein subunit L20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.5   4.4   1.7e-38   1.6e-34      56     164 .]      38     145 ..      15     145 .. 0.86

  Alignments for each domain:
  == domain 1  score: 119.5 bits;  conditional E-value: 1.7e-38
     MRP-L20  56 laakeskassk....sselPpvlkkksekekkyhltkedieeirrLraeDPekwsrkkLakkFgcsklfvsmvteapk..ekkkeveaeleavkerWge 148
                 +++++     +     ++lP+++k  ++  +kyhlt +d++eirrLr+ DP++wsr+kLa+kF+cs  f++mv+e+ +  +k+++++++leavk+rWg 
  EEA19750.1  38 VQHES-----TlsiaPEDLPWATKAPKR--QKYHLTVDDVKEIRRLRTLDPVAWSRWKLARKFDCSARFINMVCEPIPqeQKQEIHRKVLEAVKSRWGV 129
                 33333.....0333389******88777..9*******************************************865434888999999********** PP

     MRP-L20 149 krriaredRkkRkelw 164
                 +rriaredR+ Rke w
  EEA19750.1 130 TRRIAREDRELRKEAW 145
                 ***************9 PP

>> Neugrin  Neugrin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.9   8.5e-06     0.076       6      68 ..      57     119 ..      54     141 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 8.5e-06
     Neugrin   6 aPeRr...LtWeaieqiRYLkeefpeeWtvprLaeGFdvstDvirRvlkskfvPtlerklkqDakv 68 
                 aP+R+   Lt + + +iR L+   p  W+  +La  Fd s+  i  v     +P +e+k     kv
  EEA19750.1  57 APKRQkyhLTVDDVKEIRRLRTLDPVAWSRWKLARKFDCSARFINMVCEP--IP-QEQKQEIHRKV 119
                 777744449*******************************9999888643..33.44555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (149 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       585  (0.0326287); expected 358.6 (0.02)
Passed bias filter:                      383  (0.021362); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.23s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1101.50
//
Query:       EEA19751.1  [L=591]
Description: cystathionine gamma-synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.8e-32  110.9   0.0    6.3e-32  110.5   0.0    1.1  1  Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
     0.0012   18.1   0.0     0.0018   17.5   0.0    1.3  1  Aminotran_1_2    Aminotransferase class I and II


Domain annotation for each model (and alignments):
>> Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.5   0.0     7e-36   6.3e-32      61     381 ..     263     583 ..     252     584 .. 0.87

  Alignments for each domain:
  == domain 1  score: 110.5 bits;  conditional E-value: 7e-36
                      HHHHHT-SEEEEESSHHHHHHHHHHTTS-T.TE.EEEEESTSSHHHHHHHHHTHHHTTCEEEEESTTSHHHHHHHCCT..TEEEEEEESS-TTT CS
  Cys_Met_Meta_PP  61 iaaLeggeaalavssGmaAiaaailallka.Gd.eivvsddlYggtqrllkkvlkklgievkfvdtsdleelekaike..ntklvylEtptnpl 150
                      ia L + + ++++++Gm++i+++ ++ll+a G  + ++    Y  t ++l+k  +  +i + +   +++++le+ +++  +  ++++E p+npl
       EEA19751.1 263 IAGLTE-NDVFLYPTGMSSIFNTHRTLLNAkGPlKSICFGFPYTDTLKILEKWGPG-CIFYGHGSSDEIQDLESRLEKgeRFLALFTEFPGNPL 354
                      555554.468999***************9954315677777777777777776554.47777788899999**999986688899********* PP

                      T----HHHHHHHHHHTT-EEEEEGTTTHTTTS-GGGGT-SEEEEETTTTTTCSSS--EEEEEESSCHHHHHHHHH.HHHHHT-B--HHHHHHHH CS
  Cys_Met_Meta_PP 151 lkvvDiekiaklakkagvlvvvDntfaspllqrplklgaDivvhSaTKylgGhsdvvaGvivvkgkeelkkelkf.lqnalGavlspfdawlll 243
                      l  +D+++i +la k +  vvvD t+ s ++++ l++ aD+vv S +K  +G s+v++G +v + +    + lk+ ++ +    + + da  l 
       EEA19751.1 355 LTSPDLKRIRELANKYDFYVVVDETIGSFINVNVLQH-ADVVVSSLSKIFSGDSNVMGGSAVLNPQGLHYQFLKKaFTTDYEDNVWAEDAVFLE 447
                      ************************************8.9**********************9988444334333326688999999******** PP

                      HHHTTHHHHHHHHHHHHHHHHHHHHTSTTEEEEE-TTS.TTSTTHHHHHHHSSSG-SEEEEEESSHHHHHHHHHHC-SSSEECSS-SSSS-EEE CS
  Cys_Met_Meta_PP 244 rGlkTLslRlerhqenAlkvAefLekhpkvekvyYpgl.pshpqhelakkqlkgaggvlsFelkseeekakkfvdnlklfslaeslGgveslie 336
                      r  +    R+e+ + +   v e L+++p v++vyYp   p+  +++  ++ + g+gg++s + +++ + a +f d+l++++   slG   + ++
       EEA19751.1 448 RNSRDFISRIEKINTTTEFVTEILQTSPLVKEVYYPKYsPTRLNYDALRHPTGGYGGLFSITFHTT-KDAIAFFDALEVMK-GPSLGTNFT-LS 538
                      ************************************7537899****************9999988.779********986.78**97655.69 PP

                      ETTTTTTTTSCHHHHHHTTS-TTEEEEE--SS-HHHHHHHHHHHH CS
  Cys_Met_Meta_PP 337 lpasmthasipkeereaagvtddliRlsvGiEdvdDliaDlkqal 381
                      +p++   +  +++   +  v  dliR+svG+Ed ++l a +k+al
       EEA19751.1 539 CPYTLLAHYAEADWASSFNVPFDLIRVSVGLEDPEELGARFKRAL 583
                      99999999999999999*************************998 PP

>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   0.0     2e-07    0.0018     132     223 ..     329     403 ..     323     472 .. 0.86

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 2e-07
                    HHHHHHHHTTHHCTTETEEEEEEESS-TTT--B--HHHHHHHHHHHHHTTEEEEEEETTTTCBSSSSHTHHHHGGSTTSTTEEEEEESSSTT CS
  Aminotran_1_2 132 lealeealkeapegnkktkvilvesphNPtGtvatleeleklldlakkynlllfvDeaYagfvfgsldavatranveeepnllivgslsKaf 223
                    +++le  l++  e+      +++e p NP  t ++l+ +++l   a+ky ++++vDe+ + f            nv ++ + ++v+slsK f
     EEA19751.1 329 IQDLESRLEK-GERFL---ALFTEFPGNPLLTSPDLKRIREL---ANKYDFYVVVDETIGSFINV---------NVLQHAD-VVVSSLSKIF 403
                    6889999998.44555...9*********9999999999999...************97777664.........6777666.8999999988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (591 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       414  (0.0230911); expected 358.6 (0.02)
Passed bias filter:                      400  (0.0223102); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.42
# Mc/sec: 4254.52
//
Query:       EEA19752.1  [L=1110]
Description: pre-rRNA processing protein Utp22 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-57  193.8   0.3    3.8e-57  193.1   0.3    1.4  1  Nrap_D4   Nrap protein nucleotidyltransferase domain 4
    7.9e-54  181.8   0.4    1.6e-53  180.8   0.1    1.7  2  Nrap_D5   Nrap protein PAP/OAS1-like domain 5
    3.1e-42  143.9   0.5    2.2e-40  137.9   0.0    3.3  3  Nrap_D2   Nrap protein PAP/OAS-like domain
    9.7e-42  142.6   0.2    1.8e-41  141.7   0.2    1.5  1  Nrap      Nrap protein domain 1
    1.4e-41  142.2   0.0    9.1e-41  139.6   0.0    2.1  2  Nrap_D3   Nrap protein domain 3
    2.1e-29  102.4   0.0    6.4e-29  100.9   0.0    1.9  1  Nrap_D6   Nrap protein domain 6
  ------ inclusion threshold ------
      0.032   14.5   0.0       0.28   11.4   0.0    2.2  2  DUF948    Bacterial protein of unknown function (DUF948)


Domain annotation for each model (and alignments):
>> Nrap_D4  Nrap protein nucleotidyltransferase domain 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  193.1   0.3   1.5e-60   3.8e-57       2     212 ..     621     815 ..     620     816 .. 0.93

  Alignments for each domain:
  == domain 1  score: 193.1 bits;  conditional E-value: 1.5e-60
                 HHHTS--SSTTGGGS-TT--HHHHHHHHHHHHHHHHHHT-.--SS-EEEEEE-SGGGGT--SS---TT.......-.....TTSTEEEEEEE---TTS- CS
     Nrap_D4   2 ldsllrlkkassseqsstseeafssvikaFdeLekdlrsLedLPLsirsvqpaspalRytsvfppvpvklsppkaaksskeylepidvvlqfEsSgkWP 100
                 +d+ l+    + +++++++++ f+s+++aF++L+ + +s++dLPL++r++qpasp lR+t+v    p      k+       l+p+d+ lq+EsS+kWP
  EEA19752.1 621 FDETLQ----QLAGSEKQTAAMFQSIRDAFQSLQSSFQSMDDLPLQVRHLQPASPFLRSTAVISD-P------KD-----IGLTPVDINLQLESSTKWP 703
                 777777....444567888899***************************************9776.5......23.....489**************** PP

                 SSHHHHHHHHHHHHHHHHHHH.HH-TTS.EEEEEE-------...EEEEEE-TTS-EEEEEEE-TTHHHHHHHHH...HHS-TTHHHHHHHHHHHHHHH CS
     Nrap_D4 101 ddleAiqkvKaAFllkiaeeLeekksei.karvgldnssekianqayLdvlkesgfaFrlrilherEltllerqlkdkglakkereeaaealaklerrf 198
                 d+l+Aiq++K+AFll+i+e L+ ++ ++ + rvgl+n+s+++ n+a+Ld+ +++g+ Frlr +herE+tller+lk++gl+++ +e+  +al +++++f
  EEA19752.1 704 DNLDAIQMTKVAFLLRIGEALK-DDGNVtSFRVGLENESRRFINRAFLDIAHTTGIQFRLRLHHEREATLLERKLKESGLSPQYKEDIGAALFEYKKTF 801
                 **********************.6777769********9999********************************************************* PP

                 TTHHHHHHHHHHHH CS
     Nrap_D4 199 vhlprhtsaiaglc 212
                 +h+pr+t+ +++l+
  EEA19752.1 802 IHSPRLTQVVQTLS 815
                 ***********997 PP

>> Nrap_D5  Nrap protein PAP/OAS1-like domain 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.0       3.4   8.6e+03      78     104 ..     631     657 ..     602     663 .. 0.71
   2 !  180.8   0.1   6.2e-57   1.6e-53       1     160 [.     818     976 ..     818     978 .. 0.94

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 3.4
                 -----HHHHHHHHHHHHHHHHH-TTSS CS
     Nrap_D5  78 sekltaeeikeietrfealrksdpamn 104
                 sek ta+ +++i+++f++l++s ++m 
  EEA19752.1 631 SEKQTAAMFQSIRDAFQSLQSSFQSMD 657
                 455666777777777777777766665 PP

  == domain 2  score: 180.8 bits;  conditional E-value: 6.2e-57
                 -TTHHHHHHHHHHHHHHTT-T.TTS-HHHHHHHHHHHHHS-TTS----SHHHHHHHHHHHHHH--TTT--EE----------HHHHHHHHHHHHHHHHH CS
     Nrap_D5   1 fpaysptvrLvkrWlashlLleghvseelvELlvakvFlqpapysvPssaetGFlrvLelLarwdWkeepLivdlnesekltaeeikeietrfealrks 99 
                 +p++sptvrL+k+W++s+lLl +hv+ee+vELl+++v+++ +p+++Pss +tGF+r+L+lL++w+W++epLi+ +     lt e++k+ietrf a+r++
  EEA19752.1 818 YPLLSPTVRLMKHWFNSQLLL-SHVTEEFVELLAINVYVSIHPWASPSSLMTGFYRTLSLLSKWNWQQEPLILGMG---GLTGEDVKTIETRFLAWRNI 912
                 799******************.****************************************************99...7******************* PP

                 -TTSSS----EE-SS-TTS-TTT.--HH...HHHHHHHHHHHHHHHHHHH.....-SSHHH.HT CS
     Nrap_D5 100 dpamnktalfvatekDkegtlwt.kekpskvvaaRltaLAkaalelleekevse.kldvks.lF 160
                 dpam+k+ ++va++ D++g++wt +ekp kvva ++t+LAkaa+e+l++++ +e + ++++ lF
  EEA19752.1 913 DPAMKKVSMIVASDLDHDGVTWTlNEKPPKVVAGHITRLAKAAVEALKQQHGKEdRPSLENlLF 976
                 *************************************************976655333333355 PP

>> Nrap_D2  Nrap protein PAP/OAS-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.9   0.0   8.6e-44   2.2e-40       1     151 [.     322     460 ..     322     461 .. 0.92
   2 ?    1.1   0.0      0.11   2.9e+02      56      82 ..     864     890 ..     823     908 .. 0.69
   3 ?    0.2   0.1      0.23   5.8e+02      94     122 ..     993    1021 ..     970    1026 .. 0.80

  Alignments for each domain:
  == domain 1  score: 137.9 bits;  conditional E-value: 8.6e-44
                 THHHHHHHHHHHHHHTT--SS--TS-S-SHHHHHHHHHHHTSBBSTTS-BSS-TT--HHHHHHHHHHHHHHS--SS-EEEE-------BEEES-.--SS CS
     Nrap_D2   1 afkdAclLlkvWlrqRgfgssirkaggfggfewamllalllqgggkkgrkklskslssyqlfkavlqfLastdltkkpiflgaskseeskkeseeefsk 99 
                 +++dA lL+++Wlrq+gf s+i+k ggfg+few +ll ll++ggg +g+ +l +s+ssyq+fka++qfL  +dl  +p++l  s    + + +  +   
  EEA19752.1 322 SMRDASLLGQTWLRQHGFASTIEK-GGFGSFEWMLLLGLLFEGGGANGKPILLPSYSSYQVFKAAMQFLVARDL-MQPLSLFVS----DVELPAGG--- 411
                 589*********************.*************************************************.557777332....23445555... PP

                 ...--EEETTT--BTTTT--HHHHHHHHHHHHHHHHHHT-SSS--HHHHHT- CS
     Nrap_D2 100 afepvlvdpsgklNllakmtassydlLqqeAketlelLddsssdqFdslFlt 151
                    pv++d +++lN+l+kmt +sy+lL++e+++tl+lL++++ d+F+++F+ 
  EEA19752.1 412 ---PVFFDGKRGLNILYKMTIGSYKLLRHECSLTLSLLNETRFDNFEKVFIF 460
                 ...***********************************************96 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.11
                 --HHHHHHHHHHHHHHS--SS-EEEE- CS
     Nrap_D2  56 lssyqlfkavlqfLastdltkkpiflg 82 
                  s +  f  +l  L++++++++p++lg
  EEA19752.1 864 SSLMTGFYRTLSLLSKWNWQQEPLILG 890
                 5566678889*************9994 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.23
                  -.--SS...--EEETTT--BTTTT--HHH CS
     Nrap_D2   94 eeefskafepvlvdpsgklNllakmtass 122 
                  +++ +k+ +p++   +g +Nl+++ +ass
  EEA19752.1  993 SKKSKKHNQPQFANLKGLVNLASSSEASS 1021
                  334467889************99877665 PP

>> Nrap  Nrap protein domain 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  141.7   0.2     7e-45   1.8e-41       1     151 [.     174     318 ..     174     319 .. 0.92

  Alignments for each domain:
  == domain 1  score: 141.7 bits;  conditional E-value: 7e-45
                 EEEEEE--GGG--TTTTSTTHHHHHHHHHHHHHHHHHHHHHHHTGTEEEEEEEGGG-TT-EEEEEEE---.----GGGTEEEEEEEE--TTSS-GGGGS CS
        Nrap   1 VDlavemPkslfqekDylnlRyfyKRalYLavlaaelskskkkedlvkvsfeylngdelkpiLvirpkkeaekkfskskfririipvapsdlfklskls 99 
                 VD+av++P++lfq+kDy n++yf+KRa+++a++aa+l+++ k    ++++++y++gd l+pi+v++p+++a++++ k+ +riri+++++++lf++++++
  EEA19752.1 174 VDIAVTIPSTLFQPKDYRNYKYFQKRAFFIACIAASLREA-K--LPFSIQYNYQDGDLLRPIIVLEPTENASEDSPKQPIRIRILTAVEDELFPVTRTL 269
                 9************************************885.3..358**********************99***9************************ PP

                 TTS--S----........---------HHHHHHHHHTT-HHHHHHHHHHHHH CS
        Nrap 100 psknnirvetlkeekesseeeetlppTPlYNssilsdllleehlkllhkakk 151
                 ps+nn++++  +   ++ +++++++++P+YNs+++ ++++ ++ k l++  k
  EEA19752.1 270 PSRNNVQTAGAE---DEPQSNDENKSSPYYNSALRFESTVIPYQKWLQTSLK 318
                 *******65533...33456677899*********************98776 PP

>> Nrap_D3  Nrap protein domain 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.6   0.0   3.6e-44   9.1e-41      33     160 .]     486     609 ..     449     609 .. 0.86
   2 ?   -0.4   0.0      0.42   1.1e+03       4      24 ..     982    1002 ..     979    1020 .. 0.67

  Alignments for each domain:
  == domain 1  score: 139.6 bits;  conditional E-value: 3.6e-44
                 HHHHHHHHHHHHHHHHHGGGEEEEEEEEE.T-EE-TTSSS-BSSS-SEEEEEEEE-TTTTT-SEEEEEE-S--HHHHHHHHHHGGGEEEEE-TTS-EEE CS
     Nrap_D3  33 aeeallskvssvlkkaLgdRvkliaikle.eeewsiekkkskeakeskleiglllnpenaerlvdkGPsaedkeeaaeFreFWgekselRrFkDGsIle 130
                  + +++++++++l+++LgdR+k+i++ ++  ++ ++++k+ +e + ++++igl+lnpen++rlvd+GP+ae +eea++Fr+FWg+k+elRrF+DG+Ile
  EEA19752.1 486 LSVSYQNHIYDILERSLGDRAKVICLWSDsPSPQPLKSKSLNEPHFQQISIGLILNPENSNRLVDHGPAAEMQEEATAFRSFWGDKAELRRFRDGNILE 584
                 5678899********************88556999999999********************************************************** PP

                 EEE----SSS...-HHHHHHHHHHHHHT-T CS
     Nrap_D3 131 svvWeksskserrsiveqIvkyiLkrhlki 160
                 s+vW  s++    s++ qI+ y L+rhlki
  EEA19752.1 585 SLVW--SDQG---SVIDQILVYSLSRHLKI 609
                 ****..3333...7*************986 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.42
                  HSSEEEEEE--HHH-SS---H CS
     Nrap_D3    4 kfDlvlriklseekakekkee 24  
                   +D v++++++++k+k+++++
  EEA19752.1  982 PYDFVIHLNNPSKKSKKHNQP 1002
                  69*********5544433332 PP

>> Nrap_D6  Nrap protein domain 6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.9   0.0   2.5e-32   6.4e-29       1     135 []     980    1105 ..     980    1105 .. 0.91

  Alignments for each domain:
  == domain 1  score: 100.9 bits;  conditional E-value: 2.5e-32
                  --S-SEEEEEE-SS--TTTT.......TB---------------..GGGGGGS-HHHHHHHHHHHHHTTTEEEEE-S-HHEEEEEEE-GGGSS-EE- CS
     Nrap_D6    1 ledYDvvihLkpkvlprlseavaekspgakkkskfkNlderaes..dkllvkfdpvqllleeLeraygdtllffydklggdvigglwnpsvlkprkf 95  
                  l+ YD+vihL+++  +++++          ++++f Nl+   +   ++     d +  +l+eL+ +y++ +lffy++ + +vi+glw+p+++++r+f
  EEA19752.1  980 LSPYDFVIHLNNPSKKSKKH----------NQPQFANLKGLVNLasSSEASSRDITMSYLSELQTIYEHCILFFYGH-EENVIAGLWKPTSTTSRPF 1065
                  689*********88887544..........37899999987665557888889***********************9.55***************** PP

                  -TT--S-EEESSSS..EEEE-HHHHHHHHHHHHGGGEEEE CS
     Nrap_D6   96 kvnlgystkpvakekkevelNkeaileeiarlGggLvksi 135 
                  +++ +yst+p ++ ++ v+lNke+ l+eiarlGg Lv si
  EEA19752.1 1066 NLKTAYSTRPAHNGTADVTLNKESTLNEIARLGGSLVHSI 1105
                  *************************************998 PP

>> DUF948  Bacterial protein of unknown function (DUF948)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0      0.49   1.3e+03      33      65 ..      78     110 ..      74     125 .. 0.70
   2 ?   11.4   0.0   0.00011      0.28      21      87 ..     600     666 ..     597     667 .. 0.93

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.49
      DUF948  33 atieelekqvdpilkevedllakvnelledvne 65 
                 + +++l+ + d+++  v+d l+ ++++l++v e
  EEA19752.1  78 ELLAGLRPDYDKLVSTVQDNLRRIRDILQQVPE 110
                 556677777888888888888888888888865 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00011
      DUF948  21 llklkktldeaaatieelekqvdpilkevedllakvnelledvneklekvdplteavadlgesvsel 87 
                 + +l++ l+  +++i+ ++++ d++l+++++  +++ ++ + +++  +++++ ++++ dl  +v++l
  EEA19752.1 600 VYSLSRHLKISRHSIKCIGDEFDETLQQLAGSEKQTAAMFQSIRDAFQSLQSSFQSMDDLPLQVRHL 666
                 56788999999*************************************************9999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1110 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       560  (0.0312343); expected 358.6 (0.02)
Passed bias filter:                      474  (0.0264376); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.78u 0.29s 00:00:01.07 Elapsed: 00:00:00.44
# Mc/sec: 7584.72
//
Query:       EEA19753.1  [L=1250]
Description: nuclear envelope pore membrane protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1250 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       442  (0.0246528); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.78u 0.33s 00:00:01.11 Elapsed: 00:00:00.47
# Mc/sec: 7911.61
//
Query:       EEA19754.1  [L=355]
Description: ubiquitin hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.1e-37  128.9   0.0    1.3e-33  116.5   0.0    2.2  2  Peptidase_C12  Ubiquitin carboxyl-terminal hydrolase, family 
  ------ inclusion threshold ------
      0.084   12.5   0.1        0.2   11.2   0.1    1.6  1  CSTF_C         Transcription termination and cleavage factor 


Domain annotation for each model (and alignments):
>> Peptidase_C12  Ubiquitin carboxyl-terminal hydrolase, family 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.1   2.4e-05      0.22      16      41 ..      36      61 ..      29      63 .. 0.87
   2 !  116.5   0.0   1.4e-37   1.3e-33      84     210 ..      62     201 ..      60     203 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 2.4e-05
                   HHHT--S..EEEE--S.SHHHTTS-- CS
  Peptidase_C12 16 eklGvkgvqfeevyslddellaslpv 41
                   e +Gv+gv+++ev+sld+e+++slp 
     EEA19754.1 36 EPFGVQGVKIQEVVSLDEEMIDSLPH 61
                   569*************999**99985 PP

  == domain 2  score: 116.5 bits;  conditional E-value: 1.4e-37
                    -STTGHHHHHHHHHHHH..STS--.-TTSHHHHHHHHHTTS-HHHHHHHHHT-HHHHHHHTTSC......................---SSTHH.H CS
  Peptidase_C12  84 tiqnaCgtiAlLhvllNlekeaeeielgseLkkfkeftkelspeergealenseeireahnsfa....................segqteapee.e 158
                    t++naC+ +AlL+++ N++    +i+lg++L++fkeft+ ++p+ rg+a+ n ++i+++hnsfa                    s  + + +++ +
     EEA19754.1  62 TADNACASVALLNIVNNID----DITLGDTLASFKEFTMPFTPALRGDAIANFDFIKRIHNSFArsmdilnsdislkdeavvskS--SRRIDDSaS 151
                    789**************88....89*************************************************99999998542..222222255 PP

                    HS--EEEEEEEEETTEEEEE-TTS.S-EEEEE--T..TTHHHH.HHHHHHHT CS
  Peptidase_C12 159 edvafHFiafvpvngklyeLDGlkegPidlgeveeeeedledavrkviqeri 210
                    +++afHFiafvp+ g+++++DGl+++P dl++++  + d+ ++vr+++ +++
     EEA19754.1 152 NEAAFHFIAFVPALGRVWKFDGLERQPQDLAPCT--NGDWLKQVRSHLIDKM 201
                    667******************************4..68**777776655444 PP

>> CSTF_C  Transcription termination and cleavage factor C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.1   2.3e-05       0.2       9      26 ..      45      62 ..      45      63 .. 0.94

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 2.3e-05
      CSTF_C  9 lqQVLqLseeqIaaLPpd 26
                +q V +L+ee I++LP++
  EEA19754.1 45 IQEVVSLDEEMIDSLPHT 62
                899*************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (355 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       311  (0.0173462); expected 358.6 (0.02)
Passed bias filter:                      295  (0.0164538); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 2392.40
//
Query:       EEA19755.1  [L=354]
Description: ubiquitin hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.8e-54  184.1   0.0    3.5e-54  183.7   0.0    1.1  1  Peptidase_C12  Ubiquitin carboxyl-terminal hydrolase, family 


Domain annotation for each model (and alignments):
>> Peptidase_C12  Ubiquitin carboxyl-terminal hydrolase, family 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  183.7   0.0     2e-58   3.5e-54      14     210 ..       1     200 [.       1     202 [. 0.86

  Alignments for each domain:
  == domain 1  score: 183.7 bits;  conditional E-value: 2e-58
                    HHHHHT--S..EEEE--S.SHHHTTS-..--EEEEEEE.----------.---------..T...TS------STTGHHHHHHHHHHHH..STS-- CS
  Peptidase_C12  14 lleklGvkgvqfeevyslddellaslp..vyglillfkyieeeeeeeerekeeeekdeeeeevsekvfFakQtiqnaCgtiAlLhvllNlekeaee 107
                    +l+++Gv+gv+++ev+sld+e+++slp  vygli+lf++ e++  e+++  +         +  + ++Fa+Qt++naC+ +AlL+++ N++    +
     EEA19755.1   1 MLREFGVQGVKIQEVVSLDEEMIDSLPkpVYGLIFLFRWHEDN-PEKQE--A---------SCPDGLWFANQTADNACASVALLNIVNNID----D 80 
                    689***************999*****556**********9888.33332..2.........23467***********************88....8 PP

                    .-TTSHHHHHHHHHTTS-HHHHHHHHHT-HHHHHHHTTSC......................---SSTHH.HHS--EEEEEEEEETTEEEEE-TTS CS
  Peptidase_C12 108 ielgseLkkfkeftkelspeergealenseeireahnsfa....................segqteapee.eedvafHFiafvpvngklyeLDGlk 182
                    i+lg++L++fkeft+ ++p+ rg+a+ n ++i+++hnsfa                    s  + + +++ ++++afHFiafvp+ g+++++DGl+
     EEA19755.1  81 ITLGDTLASFKEFTMPFTPALRGDAIANFDFIKRIHNSFArsmdilnsdislkdeavvskS--SRRIDDSaSNEAAFHFIAFVPALGRVWKFDGLE 174
                    9*************************************************99999998542..222222255667********************* PP

                    .S-EEEEE--T..TTHHHH.HHHHHHHT CS
  Peptidase_C12 183 egPidlgeveeeeedledavrkviqeri 210
                    ++P dl++++  + d+ ++vr+++ +++
     EEA19755.1 175 RQPQDLAPCT--NGDWLKQVRSHLIDKM 200
                    *********4..68**777776655444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (354 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       333  (0.0185733); expected 358.6 (0.02)
Passed bias filter:                      318  (0.0177366); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2517.31
//
Query:       EEA19756.1  [L=293]
Description: hypothetical protein PMAA_005290 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (293 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       461  (0.0257125); expected 358.6 (0.02)
Passed bias filter:                      361  (0.020135); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 1988.10
//
Query:       EEA19757.1  [L=476]
Description: dihydrolipoamide succinyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.5e-80  270.0   0.0    2.1e-80  269.5   0.0    1.2  1  2-oxoacid_dh     2-oxoacid dehydrogenases acyltransferase (ca
    7.8e-19   67.3   2.5    1.5e-18   66.4   2.5    1.5  1  Biotin_lipoyl    Biotin-requiring enzyme
    8.8e-05   22.3   0.2     0.0024   17.6   0.1    2.4  2  Biotin_lipoyl_2  Biotin-lipoyl like
     0.0002   22.0   0.3      0.033   14.9   0.1    2.5  2  HlyD_3           HlyD family secretion protein
     0.0092   15.9   0.2       0.32   11.0   0.0    2.6  2  RnfC_N           RnfC Barrel sandwich hybrid domain
  ------ inclusion threshold ------
      0.099   12.5   0.4       0.21   11.5   0.4    1.5  1  GCV_H            Glycine cleavage H-protein
       0.38   10.3   1.3        0.5    9.9   1.3    1.1  1  Pneumo_att_G     Pneumovirinae attachment membrane glycoprote
        2.1    7.0   3.6        2.9    6.6   3.6    1.1  1  Presenilin       Presenilin
          3    7.6   9.7        4.2    7.1   9.7    1.1  1  RR_TM4-6         Ryanodine Receptor TM 4-6


Domain annotation for each model (and alignments):
>> 2-oxoacid_dh  2-oxoacid dehydrogenases acyltransferase (catalytic domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  269.5   0.0   1.1e-83   2.1e-80       3     233 .]     243     475 ..     241     475 .. 0.98

  Alignments for each domain:
  == domain 1  score: 269.5 bits;  conditional E-value: 1.1e-83
                   XXXXXXXXXXXXXXXXXXXXXX.XXXEEEEEEEEE-HHHHHHHHHHHHHHHHTT-----HHHHHHHHHHHHHHH-GGGG-EE.EES..EEEE--SS- CS
  2-oxoacid_dh   3 eeervplsgirkaiakrlteskqeiphftlsdevdvtallelrkelkekeakeekakltlldflikavalAlkefPelnasvdeee..keivvkkhv 97 
                   ee+rv+++++r +ia+rl++s+++++ +t+++evd+++l+e+rk +k++  k++ +kl +++ + +a++lA+k+ P++nas+++ +  ++iv++++v
    EEA19757.1 243 EERRVKMNRMRLRIAERLKQSQNTAASLTTFNEVDMSSLMEFRKLYKDDVLKKTGVKLGFMSAFSRACVLAMKDLPAVNASIEGPNggDTIVYRDYV 339
                   799***********************************************98888***************************87777789******* PP

                   -EEEE--------EEEE--GGG--HHHHHHHHHHHHHHHTTT---GGGTSS-SEEEE---------------TT-SEEEEE---.B--TTSTT-HT- CS
  2-oxoacid_dh  98 niGvAvatprGLlvPviknadkkslleiakelkelaekaregklkpedleggtftisNlGmlGvtsftPiinppqvaIlgvgrikerpvvkegelvv 194
                   +i+vAvat++GL++Pv++na+ ++l+ i+k++++l +kar++kl+ ed+ ggtftisN G++G+ ++tPiin pq+a+lg+++ikerpvv++g+++v
    EEA19757.1 340 DISVAVATEKGLVTPVVRNAEGMDLVGIEKAIADLGKKARDNKLTIEDMAGGTFTISNGGVFGSLMGTPIINLPQTAVLGLHAIKERPVVVNGKVEV 436
                   ************************************************************************************************* PP

                   --EEEEEEEEETTT--HHHHHHHHHHHHHTT-HHXXXXX CS
  2-oxoacid_dh 195 rkvmtlslsaDHRvidGaeaarFlntlkkllenpeelll 233
                   r++m+l l++DHR++dG ea+ Fl ++k+++e+p ++ll
    EEA19757.1 437 RPMMYLALTYDHRLLDGREAVTFLVKVKEYIEDPRRMLL 475
                   ************************************985 PP

>> Biotin_lipoyl  Biotin-requiring enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.4   2.5   7.3e-22   1.5e-18       3      73 .]      98     169 ..      96     169 .. 0.98

  Alignments for each domain:
  == domain 1  score: 66.4 bits;  conditional E-value: 7.3e-22
                    EEESSSEEEEEE..ECSESSSTTCEE-TTSEEEEEECTTEEEEEEBSSSEEEEEESSTTTEEE-TTCEEEEE CS
  Biotin_lipoyl   3 iksPmiGesveeg.vvevlvkvGdkVkagqvlaeveamKmemeieapkaGvvkeilvkeGdtvevgdllaki 73 
                    +k+P+++es++eg   ++ ++vGd V+ ++ +a++e++K  + ++ap++G++ke+lv+e dtv+vg++++k+
     EEA19757.1  98 VKVPEMAESITEGtLKQFSKQVGDFVERDEEIATIETDKIDVAVNAPESGTIKELLVSEEDTVTVGQPIVKL 169
                    89********************************************************************97 PP

>> Biotin_lipoyl_2  Biotin-lipoyl like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.0     0.015        30      10      43 ..     109     142 ..     103     145 .. 0.88
   2 !   17.6   0.1   1.2e-06    0.0024       3      35 ..     139     171 ..     138     172 .. 0.94

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.015
  Biotin_lipoyl_2  10 sGrVaqlnVkdGqrVkaGdvLaelDsralqlala 43 
                       G+++q   + G+ V+    +a++++++ ++a++
       EEA19757.1 109 EGTLKQFSKQVGDFVERDEEIATIETDKIDVAVN 142
                      68889999999*****************999986 PP

  == domain 2  score: 17.6 bits;  conditional E-value: 1.2e-06
  Biotin_lipoyl_2   3 vsIaapvsGrVaqlnVkdGqrVkaGdvLaelDs 35 
                      v + ap sG++++l+V + + V  G+ ++ l++
       EEA19757.1 139 VAVNAPESGTIKELLVSEEDTVTVGQPIVKLEP 171
                      78999************************9986 PP

>> HlyD_3  HlyD family secretion protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.016        32       8      35 ..     110     136 ..     106     142 .. 0.82
   2 !   14.9   0.1   1.7e-05     0.033       2      32 ..     141     171 ..     140     178 .. 0.92

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.016
      HlyD_3   8 Gvvvelnveegevvqagdelleiippdt 35 
                 G++++ + ++g++v++ +e+++i   d+
  EEA19757.1 110 GTLKQFSKQVGDFVERDEEIATIET-DK 136
                 88999999***************94.44 PP

  == domain 2  score: 14.9 bits;  conditional E-value: 1.7e-05
      HlyD_3   2 lrApvdGvvvelnveegevvqagdelleiip 32 
                 ++Ap +G+++el v+e++ v+ g++++++ p
  EEA19757.1 141 VNAPESGTIKELLVSEEDTVTVGQPIVKLEP 171
                 89*************************9987 PP

>> RnfC_N  RnfC Barrel sandwich hybrid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.0   0.00016      0.32      45      79 ..     116     151 ..     100     153 .. 0.88
   2 ?    3.2   0.0     0.041        82      43      60 ..     151     168 ..     150     173 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00016
      RnfC_N  45 lvkvgdkVlkGqkiaeaeg.fvsapvhasvsGtVka 79 
                   +vgd V++ + ia+ e+  + ++v a+ sGt+k+
  EEA19757.1 116 SKQVGDFVERDEEIATIETdKIDVAVNAPESGTIKE 151
                 5689***********9987788************97 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.041
      RnfC_N  43 kplvkvgdkVlkGqkiae 60 
                 ++lv+++d+V+ Gq i +
  EEA19757.1 151 ELLVSEEDTVTVGQPIVK 168
                 679************976 PP

>> GCV_H  Glycine cleavage H-protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.4   0.00011      0.21      39      73 ..     117     151 ..      97     162 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00011
                 --TT-EE-TT-EEEEEEESS-EEEEE-SSSEEEEE CS
       GCV_H  39 pevgtkvkkgeslaavEsvKaasevyapvsGevve 73 
                 ++vg+ v+ +e++a++E+ K    v ap sG++ e
  EEA19757.1 117 KQVGDFVERDEEIATIETDKIDVAVNAPESGTIKE 151
                 789******************************88 PP

>> Pneumo_att_G  Pneumovirinae attachment membrane glycoprotein G
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   1.3   0.00025       0.5     214     308 ..     147     241 ..     125     321 .. 0.64

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00025
  Pneumo_att_G 214 astesvltedtatskssepqleprpsqrGkst.sdkeassttsqdsstrgdskkhtqrrktppatenrrsilstatppettkiqetrkptpkptae 308
                    +++ +l ++  t + ++p ++ +p + G+++  +k+ ++ ++++++t++   k + +   p+ +e  ++  +   p +t +++e++ +tp +   
    EEA19757.1 147 GTIKELLVSEEDTVTVGQPIVKLEPGSGGEAAeKPKHEPAPEKKEEKTEASPSKPETKEAAPSKPEPVKEK-QPERPKPTEPRKEAEPSTPAQAGG 241
                   55666666666777777777777776668765268999999999999999888877777766666655555.9999**********9999987654 PP

>> Presenilin  Presenilin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   3.6    0.0014       2.9     245     326 ..     184     302 ..     145     303 .. 0.42

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.0014
  Presenilin 245 keeasesskeeeseeesseksaqsse.....seeeseeesseaessaeesseekeseessesseeeeeeeeeeeeses..................... 317
                 + + +++++++e++ +++e+++ + +     +   +++ ++++++++++++e+++ +++  ++e++ + +       +                     
  EEA19757.1 184 EPAPEKKEEKTEASPSKPETKEAAPSkpepvK---EKQPERPKPTEPRKEAEPSTPAQAGGREERRVKMN-------Rmrlriaerlkqsqntaasltt 272
                 11111111111111111111111111221211...11111111111111111111111111111111111.......0112223344445556667778 PP

  Presenilin 318 .....................eergvkLGL 326
                                      +++gvkLG+
  EEA19757.1 273 fnevdmsslmefrklykddvlKKTGVKLGF 302
                 888888888888888888887778999997 PP

>> RR_TM4-6  Ryanodine Receptor TM 4-6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   9.7    0.0021       4.2      22     172 ..     127     275 ..     106     282 .. 0.71

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0021
                 XXXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXX CS
    RR_TM4-6  22 eeeesleedlaeaageeeeedllsdvfgldlkkeggqykvvakkseagLgDlseteaeesptpelkkklaeeeeaeeekeeeeepeaeaeekadaenge 120
                 ee +++e+d  ++a+++ e+ ++++++    +++  +      k e+g g    ++++++p+pe+k++++e++ ++ e++e+  +++e+ ++++ e+ +
  EEA19757.1 127 EEIATIETDKIDVAVNAPESGTIKELLVS--EEDTVTVGQPIVKLEPGSGGEAAEKPKHEPAPEKKEEKTEASPSKPETKEAAPSKPEPVKEKQPERPK 223
                 34444455555667777777777776543..33333333344667777777777777777789999999999999999999999999999999888888 PP

                 XXXXXXX..........XXXXXXXXXXXXXXXXXXXXXXXXX-HHHHHHHHH CS
    RR_TM4-6 121 keekekekeeeekeseeeeeekkkkkkakskkkeeaeaeesellkklevyqt 172
                  +e +ke e ++ +++   ee + k ++++ + +e  ++++++ ++l ++++
  EEA19757.1 224 PTEPRKEAEPSTPAQAGGREERRVKMNRMRLRIAERLKQSQNTAASLTTFNE 275
                 8888888777777777777888888888888999999999999998888875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (476 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       876  (0.0488594); expected 358.6 (0.02)
Passed bias filter:                      528  (0.0294495); expected 358.6 (0.02)
Passed Vit filter:                        79  (0.00440627); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.64u 0.28s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 3198.76
//
Query:       EEA19758.1  [L=99]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.9e-10   39.3   0.5    6.5e-10   38.9   0.5    1.2  1  Complex1_LYR  Complex 1 protein (LYR family)


Domain annotation for each model (and alignments):
>> Complex1_LYR  Complex 1 protein (LYR family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.9   0.5   3.6e-14   6.5e-10       3      58 ..       6      62 ..       4      63 .. 0.86

  Alignments for each domain:
  == domain 1  score: 38.9 bits;  conditional E-value: 3.6e-14
  Complex1_LYR  3 vLsLYRalLRearkfpdyntreyf...rrriRdeFrknkhvtDpekieellkkgreeLe 58
                  + sLYR+ L+ a  +++   r+ +   + +iR  F++nk+v+Dp++ + ll++ +++Le
    EEA19758.1  6 AASLYRRSLKLA--LDWAVHRHIWrgqAVYIRSLFDANKDVRDPRQQKLLLRETEKLLE 62
                  679*********..55555555555559*****************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (99 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       319  (0.0177924); expected 358.6 (0.02)
Passed bias filter:                      279  (0.0155614); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.45
# Mc/sec: 666.48
//
Query:       EEA19759.1  [L=133]
Description: histone H2A [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.3e-21   74.4   2.8    7.6e-21   73.6   2.8    1.4  1  Histone_H2A_C  C-terminus of histone H2A
    2.8e-17   63.3   0.0    3.8e-17   62.9   0.0    1.2  1  Histone        Core histone H2A/H2B/H3/H4
      1e-05   25.7   0.0    1.3e-05   25.3   0.0    1.2  1  CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) a


Domain annotation for each model (and alignments):
>> Histone_H2A_C  C-terminus of histone H2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.6   2.8   1.3e-24   7.6e-21       1      35 []      93     127 ..      93     127 .. 0.97

  Alignments for each domain:
  == domain 1  score: 73.6 bits;  conditional E-value: 1.3e-24
  Histone_H2A_C   1 EELnkLLggVTIAqGGVLPnIhkvLLpkktkkkkk 35 
                    EELnkLLg+VTIAqGGVLPnIh++LLpkkt k+ k
     EEA19759.1  93 EELNKLLGHVTIAQGGVLPNIHQNLLPKKTPKSGK 127
                    9******************************9976 PP

>> Histone  Core histone H2A/H2B/H3/H4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.9   0.0   6.4e-21   3.8e-17      51     129 ..      13      90 ..       7      92 .. 0.96

  Alignments for each domain:
  == domain 1  score: 62.9 bits;  conditional E-value: 6.4e-21
                 HHHHHHXXSXXSXHHHHHHHHHHHH.TTSSSXEEXHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTXSEEXHHHHHHHHH CS
     Histone  51 irkyqkstdlliqklpfaRvvreivksekedlrisaeavlalqealEallvelfeeAnllakhaKRvTitpkDiqlArr 129
                  +++q+++ + + ++p+ Rv+r ++k     +r+ a a+++l+++lE+l +e++e+A+++a+++K+ +i p+++qlA+r
  EEA19759.1  13 SKNSQSRSSKAGLAFPVGRVHRLLRK-GNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIR 90 
                 6899*********************9.9999***********************************************9 PP

>> CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) and archaeal histone
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.3   0.0   2.2e-09   1.3e-05       3      65 .]      27      89 ..      25      89 .. 0.97

  Alignments for each domain:
  == domain 1  score: 25.3 bits;  conditional E-value: 2.2e-09
                   XXHHHHHHHHHCCTTXS-B-HHHHHHHHHHHHHHHHHHHHHHHHHHCCTTSSCE-HHHHHHHH CS
  CBFD_NFYB_HMF  3 LPiarvkkImksdpdarkiakdAkeliaecveefieelaseAaeickkekrKtikaehiklAv 65
                   +P+ rv +++++ + a+++   A++++a ++e  + e+++ A   + ++k+  i + h++lA+
     EEA19759.1 27 FPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAI 89
                   9***********************************************************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (133 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       269  (0.0150036); expected 358.6 (0.02)
Passed bias filter:                      228  (0.0127168); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.42u 0.28s 00:00:00.70 Elapsed: 00:00:00.44
# Mc/sec: 914.19
//
Query:       EEA19760.1  [L=220]
Description: histone H2A [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.7e-17   61.6   0.0    1.4e-16   61.1   0.0    1.1  1  Histone        Core histone H2A/H2B/H3/H4
    5.8e-15   54.7   0.2    1.1e-14   53.8   0.2    1.5  1  Histone_H2A_C  C-terminus of histone H2A
    2.7e-05   24.3   0.0      4e-05   23.8   0.0    1.3  1  CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) a


Domain annotation for each model (and alignments):
>> Histone  Core histone H2A/H2B/H3/H4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.1   0.0   2.3e-20   1.4e-16      51     129 ..      13      90 ..       8      92 .. 0.96

  Alignments for each domain:
  == domain 1  score: 61.1 bits;  conditional E-value: 2.3e-20
                 HHHHHHXXSXXSXHHHHHHHHHHHH.TTSSSXEEXHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTXSEEXHHHHHHHHH CS
     Histone  51 irkyqkstdlliqklpfaRvvreivksekedlrisaeavlalqealEallvelfeeAnllakhaKRvTitpkDiqlArr 129
                  +++q+++ + + ++p+ Rv+r ++k     +r+ a a+++l+++lE+l +e++e+A+++a+++K+ +i p+++qlA+r
  EEA19760.1  13 SKNSQSRSSKAGLAFPVGRVHRLLRK-GNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIR 90 
                 6899*********************9.9999***********************************************9 PP

>> Histone_H2A_C  C-terminus of histone H2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.8   0.2   1.9e-18   1.1e-14       1      23 [.      93     115 ..      93     118 .. 0.96

  Alignments for each domain:
  == domain 1  score: 53.8 bits;  conditional E-value: 1.9e-18
  Histone_H2A_C   1 EELnkLLggVTIAqGGVLPnIhk 23 
                    EELnkLLg+VTIAqGGVLPnIh+
     EEA19760.1  93 EELNKLLGHVTIAQGGVLPNIHQ 115
                    9*********************8 PP

>> CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) and archaeal histone
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.0   6.7e-09     4e-05       3      65 .]      27      89 ..      25      89 .. 0.97

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 6.7e-09
                   XXHHHHHHHHHCCTTXS-B-HHHHHHHHHHHHHHHHHHHHHHHHHHCCTTSSCE-HHHHHHHH CS
  CBFD_NFYB_HMF  3 LPiarvkkImksdpdarkiakdAkeliaecveefieelaseAaeickkekrKtikaehiklAv 65
                   +P+ rv +++++ + a+++   A++++a ++e  + e+++ A   + ++k+  i + h++lA+
     EEA19760.1 27 FPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAI 89
                   9***********************************************************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (220 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       382  (0.0213063); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.42u 0.24s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 1587.28
//
Query:       EEA19761.1  [L=140]
Description: histone H2B [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.5e-21   77.1   0.6    1.9e-21   76.8   0.6    1.1  1  Histone        Core histone H2A/H2B/H3/H4
    0.00021   21.5   0.0    0.00021   21.5   0.0    1.8  2  CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) a
    0.00042   20.8   0.0     0.0007   20.0   0.0    1.3  1  TFIID_20kDa    Transcription initiation factor TFIID subunit 
  ------ inclusion threshold ------
      0.038   14.0   0.2      0.045   13.8   0.2    1.1  1  YscO-like      YscO-like protein
      0.044   13.4   0.1       0.11   12.2   0.1    1.6  1  RP-C           Replication protein C N-terminal domain


Domain annotation for each model (and alignments):
>> Histone  Core histone H2A/H2B/H3/H4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.8   0.6   5.3e-25   1.9e-21      18     130 ..       3     114 ..       1     115 [. 0.85

  Alignments for each domain:
  == domain 1  score: 76.8 bits;  conditional E-value: 5.3e-25
                 XXXXXXXXHT..TS-SSSSB--TTT-XTTH.HHHHHHHHHHHXXSXXSXHHHHHHHHHHHH.TTSSSXEEXHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
     Histone  18 ekkvsakker..kasskskkkkkrryrpgt.valkeirkyqkstdlliqklpfaRvvreivksekedlrisaeavlalqealEallvelfeeAnllakh 113
                 +k+ ++k+ +  ka++ +++++k+ + ++t  a + ++k++ +t++++++ ++++v++++++    d +is +a+ +l+++++++++++++eA++la +
  EEA19761.1   3 PKAAEKKPSTggKAPAGKAPAEKKEAGKKTaTAATGEKKKRGKTRKETYSSYIYKVLKQVHP----DTGISTRAMSILNSFVNDIFERVATEASKLASY 97 
                 555555555577666666666666665555167889999999********************....********************************* PP

                 TTXSEEXHHHHHHHHHH CS
     Histone 114 aKRvTitpkDiqlArrl 130
                 +K++Ti +++iq+ +rl
  EEA19761.1  98 NKKSTISSREIQTSVRL 114
                 *************9997 PP

>> CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) and archaeal histone
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.6       2.3   8.3e+03      43      56 ..      20      33 ..      18      37 .. 0.70
   2 !   21.5   0.0   5.9e-08   0.00021       8      64 ..      55     111 ..      53     112 .. 0.93

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 2.3
                   HHHHHHCCTTSSCE CS
  CBFD_NFYB_HMF 43 eAaeickkekrKti 56
                   +A  + k++++Kt 
     EEA19761.1 20 KAPAEKKEAGKKTA 33
                   56666788899985 PP

  == domain 2  score: 21.5 bits;  conditional E-value: 5.9e-08
                    HHHHHHCC.TTXS-B-HHHHHHHHHHHHHHHHHHHHHHHHHHCCTTSSCE-HHHHHHH CS
  CBFD_NFYB_HMF   8 vkkImksd.pdarkiakdAkeliaecveefieelaseAaeickkekrKtikaehiklA 64 
                    + k++k+  pd++ i+  A  +++ +v    e++a+eA+++++ +k+ ti+   i+  
     EEA19761.1  55 IYKVLKQVhPDTG-ISTRAMSILNSFVNDIFERVATEASKLASYNKKSTISSREIQTS 111
                    779*****88888.*************************************9999876 PP

>> TFIID_20kDa  Transcription initiation factor TFIID subunit A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   0.0   1.9e-07    0.0007       7      60 ..      57     110 ..      53     115 .. 0.93

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 1.9e-07
                  HHHHCC-SS----HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-SEE-HHHHHH CS
  TFIID_20kDa   7 dLvqqvdsetkldedvedlLleiaddFvesvtkfacklakhRksdklevrDiql 60 
                    ++qv ++t +      +L   ++d  e v + a+kla + k +++++r iq 
   EEA19761.1  57 KVLKQVHPDTGISTRAMSILNSFVNDIFERVATEASKLASYNKKSTISSREIQT 110
                  6799************************************************95 PP

>> YscO-like  YscO-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.2   1.3e-05     0.045      20     109 ..      23     110 ..      15     132 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.3e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHH---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   YscO-like  20 AEkvvkdkkkaLekEkeklrkleeerdkvkkhkkaKvaqlree.ldkGttsdkikkmkryikvvkeelkqeekkvekQkekVkvAerkvEq 109
                 AEk  + kk a ++  ek +k+ + r ++   ++ Kv  l+++  d G ++ ++ +++++++ + e+++ e+ k+++ ++k ++ +r++  
  EEA19761.1  23 AEKKEAGKKTATAATGEK-KKRGKTRKETYSSYIYKV--LKQVhPDTGISTRAMSILNSFVNDIFERVATEASKLASYNKKSTISSREIQT 110
                 444444444444433333.333444445555555555..55541599***************************************99876 PP

>> RP-C  Replication protein C N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.1     3e-05      0.11      15      83 ..      39     110 ..      25     115 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 3e-05
        RP-C  15 eaieakkkg...vdkwqllralkeakaalgvsdralavLdaLlsftpeddlseearlivfpsNaqLs.ralgl 83 
                 e+ ++ k     +  + +++ lk+  +  g+s ra+++L+ +++   e+  +e ++l  +    ++s r+++ 
  EEA19761.1  39 EKKKRGK-TrkeTYSSYIYKVLKQVHPDTGISTRAMSILNSFVNDIFERVATEASKLASYNKKSTISsREIQT 110
                 2222222.0223778899**************************99999999999999888888888777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (140 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       969  (0.0540465); expected 358.6 (0.02)
Passed bias filter:                      434  (0.0242066); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.43
# Mc/sec: 968.64
//
Query:       EEA19762.1  [L=489]
Description: autophagy cysteine endopeptidase Atg4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-97  326.7   0.0    1.5e-97  326.3   0.0    1.1  1  Peptidase_C54  Peptidase family C54
  ------ inclusion threshold ------
       0.02   14.3   0.0      0.054   13.0   0.0    1.7  2  Peptidase_C78  Peptidase family C78


Domain annotation for each model (and alignments):
>> Peptidase_C54  Peptidase family C54
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  326.3   0.0  1.7e-101   1.5e-97       4     275 ..     153     441 ..     150     442 .. 0.95

  Alignments for each domain:
  == domain 1  score: 326.3 bits;  conditional E-value: 1.7e-101
  Peptidase_C54   4 flkdfesriwltYRkeFppieks........................gltsDaGWGCmlRsgQmllaqalllhllgrdwrreeksekkeeetyrki 75 
                    fl+dfes+iw+tYR++Fppi++s                        g+tsD+GWGCm+RsgQmlla+al +  lgrdwrr      +++++ +k+
     EEA19762.1 153 FLDDFESKIWMTYRSNFPPIARSedanaaqamtlsvrlrsqltehhqGFTSDTGWGCMIRSGQMLLANALAISRLGRDWRRV-----SHTTEENKL 243
                    99********************9**********************************************************5.....33455679* PP

  Peptidase_C54  76 lslFlDkpsapfSihrlvkigk.slgkkvgeWfgPstvaqilkklvekakeeaglkvyvaqdssvvykddvkklakeskkekeekkwkpvlilvpl 170
                    lslF+D+p apfSihr+v++g+  +gk++geWfgPs++a+++++l e +++ ag++vyv++ds+ vy+d++k++a +     +  +++p+lil+++
     EEA19762.1 244 LSLFADDPAAPFSIHRFVRHGAlYCGKHPGEWFGPSATATCIQALSE-EYKVAGMNVYVSSDSTYVYEDKFKAVAYN-----QPGHMRPTLILLGT 333
                    **********************99***********************.88889******************866655.....57788********* PP

  Peptidase_C54 171 rlGldkvnpkyvealkellklkqsvGiiGGrpksslYfvgvqedkliyLDPHtvqeav...edeaeseeelssfhckkprklsiskldpslllgfl 263
                    rlG+d+++p+y + l++llkl+qs+Gi+GGrp+ss+Yf+gvq++ ++yLDPH++++a+    d+a+++e+++s+h++++r+++i+++dps+l+gfl
     EEA19762.1 334 RLGIDRITPVYRKGLEDLLKLPQSLGIAGGRPSSSHYFIGVQNSFFFYLDPHHTRPALphkVDSAYTQEQVDSCHTRRLRRIHIDDMDPSMLVGFL 429
                    *********************************************************98886789******************************* PP

  Peptidase_C54 264 ckdeedfedlve 275
                    ++de+d+ d+++
     EEA19762.1 430 IRDENDWIDWKR 441
                    *********986 PP

>> Peptidase_C78  Peptidase family C78
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   6.1e-06     0.054       9      39 ..     192     222 ..     185     320 .. 0.81
   2 ?   -2.4   0.0       0.3   2.7e+03     169     185 ..     378     394 ..     346     415 .. 0.66

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 6.1e-06
                    --BE--TCSSS--TTTTHHHHHHHHHHHHHH CS
  Peptidase_C78   9 syevdhyqskledkGwgCgYRnlQmllSwll 39 
                    s  ++h+q  + d+GwgC  R+ Qmll   l
     EEA19762.1 192 SQLTEHHQGFTSDTGWGCMIRSGQMLLANAL 222
                    445677799999**************97655 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.3
                    EEEEE--S--SSS-.HH CS
  Peptidase_C78 169 nlLvlDPhftgaeeikk 185
                     +  lDPh+t+++  +k
     EEA19762.1 378 FFFYLDPHHTRPALPHK 394
                    46678999998775333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (489 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       712  (0.0397122); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.44
# Mc/sec: 3325.64
//
Query:       EEA19763.1  [L=534]
Description: R3H and G-patch domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    8.2e-14   51.3   0.0    1.6e-13   50.4   0.0    1.5  1  R3H         R3H domain
    5.7e-10   38.9   1.8    7.2e-10   38.6   0.3    2.1  2  G-patch     G-patch domain
    0.00086   19.3   0.3    0.00086   19.3   0.3    2.7  2  G-patch_2   G-patch domain
  ------ inclusion threshold ------
        7.8    7.1   8.7       0.17   12.4   0.4    2.3  3  Rotamase_3  PPIC-type PPIASE domain


Domain annotation for each model (and alignments):
>> R3H  R3H domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.4   0.0   3.6e-17   1.6e-13       9      60 .]     368     419 ..     363     419 .. 0.96

  Alignments for each domain:
  == domain 1  score: 50.4 bits;  conditional E-value: 3.6e-17
                 HHHHHHH-S--EEE-----SHHHHHHHHHHHHSSEEEEEE--SS-SEEEEEE CS
         R3H   9 klaefvkdtgrslefppmssyeRriiHelaeaygleseSvGeepkRrvvvtk 60 
                 +l +f+++++ sl +ppm + +Rr+iHela+a  l+s+S+G+++ R  v++k
  EEA19763.1 368 ELKSFLQSQSDSLDLPPMKKNHRRVIHELANALALKSQSRGKGNARFPVLYK 419
                 6899**********************************************97 PP

>> G-patch  G-patch domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.1       3.1   1.4e+04      16      23 ..     184     193 ..     184     195 .. 0.65
   2 !   38.6   0.3   1.6e-13   7.2e-10       2      43 ..     492     534 .]     491     534 .] 0.97

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 3.1
     G-patch  16 pGqGLG..kk 23 
                 p  GLG  k+
  EEA19763.1 184 PEDGLGltKE 193
                 5679996554 PP

  == domain 2  score: 38.6 bits;  conditional E-value: 1.6e-13
     G-patch   2 sniGvkmLqkmGWkpGqGLG.kkeqGiaePieakikkdraGlG 43 
                 +n+G  mL+kmGW+ G+ LG  +++Gi +P+   +k  raGlG
  EEA19763.1 492 DNKGRAMLEKMGWSSGTALGaLNNKGILQPVVHVVKNTRAGLG 534
                 79****************************************8 PP

>> G-patch_2  G-patch domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   1.0      0.56   2.5e+03      40      57 ..     333     362 ..     319     366 .. 0.53
   2 !   19.3   0.3   1.9e-07   0.00086      15      56 ..     492     534 .]     486     534 .] 0.84

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.56
   G-patch_2  40 r...........vkpeepkrRpg.rlGLGa 57 
                 +           ++ ++ +rR + + G G+
  EEA19763.1 333 EreklraegllgKNKKKLDRRGKdKSGFGT 362
                 134455555555566666777666777776 PP

  == domain 2  score: 19.3 bits;  conditional E-value: 1.9e-07
   G-patch_2  15 eeFGaAlLrGMGWkegqgigknkkgr.vkpeepkrRpgrlGLG 56 
                 ++ G A+L  MGW+ g++ g  +++   +p++   + +r+GLG
  EEA19763.1 492 DNKGRAMLEKMGWSSGTALGALNNKGiLQPVVHVVKNTRAGLG 534
                 6779***************9855554499999999999****9 PP

>> Rotamase_3  PPIC-type PPIASE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.1      0.64   2.9e+03      11      58 ..     114     160 ..     105     169 .. 0.66
   2 ?   12.4   0.4   3.8e-05      0.17      27      66 ..     228     268 ..     218     271 .. 0.83
   3 ?   -3.5   0.3       3.3   1.5e+04      29      44 ..     327     343 ..     314     349 .. 0.50

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.64
  Rotamase_3  11 sakdsvkvshIlistkgkesrseeeakakadsllaalk.egadFaalAk 58 
                 +++++++ s+I +s++  ++r++ +ak k +++ + +  + + Fa+ +k
  EEA19763.1 114 QDPENLQDSYIGLSLSR-QTRNKRNAK-KNNKIKKSIWdDDSVFADYVK 160
                 56777778888888755.555655554.557777777656666766655 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 3.8e-05
  Rotamase_3  27 g.kesrseeeakakadsllaalkegadFaalAkeySdDpas 66 
                 + +e+++e+e  +  d++++++++ga+F++l +++ +D  s
  EEA19763.1 228 DdDEDSDETEDSSMLDDIISQIRRGASFKELEAHWANDDMS 268
                 246778888889*******************9999998765 PP

  == domain 3  score: -3.5 bits;  conditional E-value: 3.3
  Rotamase_3  29 esrseeea.kakadsll 44 
                 +  ++ e+ k +a+ ll
  EEA19763.1 327 KAAKKREReKLRAEGLL 343
                 22222222255555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (534 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       995  (0.0554967); expected 358.6 (0.02)
Passed bias filter:                      448  (0.0249875); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.46
# Mc/sec: 3502.79
//
Query:       EEA19764.1  [L=522]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    5.2e-24   84.1   0.5    1.3e-23   82.9   0.5    1.7  1  DnaJ         DnaJ domain
    3.5e-11   43.1  12.3    7.5e-08   32.5   3.7    2.5  2  zf-met       Zinc-finger of C2H2 type
    6.6e-11   42.2  14.6    1.1e-08   35.2   7.5    2.5  2  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
    3.6e-07   30.4  10.4    0.00088   19.6   2.1    2.5  2  zf-C2H2_2    C2H2 type zinc-finger (2 copies)
    2.1e-06   28.0   7.0      0.013   16.2   0.8    2.9  2  zf-C2H2_4    C2H2-type zinc finger
    2.6e-05   24.4   9.6      0.046   14.2   1.1    2.7  2  zf-C2H2      Zinc finger, C2H2 type
  ------ inclusion threshold ------
       0.03   14.3   0.0        0.1   12.5   0.0    1.9  1  RPT          A repeated domain in UCH-protein
      0.068   13.2  11.7      0.046   13.7   3.4    2.4  2  zf-C2H2_6    C2H2-type zinc finger
        1.5    9.1   4.6        1.3    9.3   0.8    2.3  2  LIM          LIM domain


Domain annotation for each model (and alignments):
>> DnaJ  DnaJ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.9   0.5   6.3e-27   1.3e-23       1      63 []      23      86 ..      23      86 .. 0.95

  Alignments for each domain:
  == domain 1  score: 82.9 bits;  conditional E-value: 6.3e-27
                HHHHHHTSSTTG-HHHHHHHHHHHHHHHSTTTSCCHH.HHHHHHHHHHHHHHHHTSHHHHHHHH CS
        DnaJ  1 dyYeiLgvskdasedeIkkaYrklalkyHPDknpkdp.eaeekFkeineAyevLsdpekRkqYD 63
                dyYe+Lgv++da +deIkkaYr++al++HPD+n ++    ++ F e++ AyevLsdp++R++YD
  EEA19764.1 23 DYYELLGVERDAADDEIKKAYRRKALELHPDRNYGQVeATTKLFAEVQCAYEVLSDPQERAWYD 86
                8********************************9999455667********************9 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.5   3.7   3.7e-11   7.5e-08       1      25 []     319     343 ..     319     343 .. 0.98
   2 !   15.3   1.4   9.6e-06     0.019       3      21 ..     485     503 ..     484     503 .. 0.95

  Alignments for each domain:
  == domain 1  score: 32.5 bits;  conditional E-value: 3.7e-11
      zf-met   1 fyCelCnvtfnsesqlksHlqGKkH 25 
                 f+C +Cn+ f+s++q+++H ++KkH
  EEA19764.1 319 FECVVCNKLFKSQKQFEAHEKSKKH 343
                 89*********************** PP

  == domain 2  score: 15.3 bits;  conditional E-value: 9.6e-06
      zf-met   3 CelCnvtfnsesqlksHlq 21 
                 C  C+ +f+s++ql sHl+
  EEA19764.1 485 CTHCQAMFSSRTQLFSHLR 503
                 *****************97 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.2   7.5   5.3e-12   1.1e-08       2      26 ..     319     343 ..     318     344 .. 0.97
   2 !   11.1   0.6    0.0002      0.39       1      22 [.     482     503 ..     482     507 .. 0.89

  Alignments for each domain:
  == domain 1  score: 35.2 bits;  conditional E-value: 5.3e-12
                  CBBTTTTBBBSSHHHHHCCTTSHHH CS
  zf-C2H2_jaz   2 fYCvlCdKyFksenaldnHlkSKkH 26 
                  f+Cv+C+K Fks++++++H+kSKkH
   EEA19764.1 319 FECVVCNKLFKSQKQFEAHEKSKKH 343
                  99*********************** PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.0002
                  ECBBTTTTBBBSSHHHHHCCTT CS
  zf-C2H2_jaz   1 qfYCvlCdKyFksenaldnHlk 22 
                  q  C +C+ +F+s  +l  Hl+
   EEA19764.1 482 QNKCTHCQAMFSSRTQLFSHLR 503
                  568*************998887 PP

>> zf-C2H2_2  C2H2 type zinc-finger (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   2.1   4.4e-07   0.00088      39      81 ..     308     349 ..     279     357 .. 0.85
   2 !   15.2   1.3   9.9e-06      0.02      48      82 ..     480     514 ..     461     522 .] 0.80

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 4.4e-07
   zf-C2H2_2  39 lleylrekieekleClyCekefkslealreHmkkkgHckinee 81 
                 +++  ++++e+ +eC++C+k fks++++++H k+k+H k  ++
  EEA19764.1 308 FFSSSESEVEH-FECVVCNKLFKSQKQFEAHEKSKKHIKAVKQ 349
                 55566677887.*************************997554 PP

  == domain 2  score: 15.2 bits;  conditional E-value: 9.9e-06
   zf-C2H2_2  48 eekleClyCekefkslealreHmkkkgHckineee 82 
                 + +++C +C+  f+s+ +l +H+++ gH + ++++
  EEA19764.1 480 DAQNKCTHCQAMFSSRTQLFSHLREIGHAQPAQSR 514
                 5589************************9965433 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.7   2.9e-05     0.057       1      22 [.     319     340 ..     319     342 .. 0.94
   2 !   16.2   0.8   6.7e-06     0.013       2      21 ..     484     503 ..     483     505 .. 0.94

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2.9e-05
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlkt 22 
                 f+C +C+k F+s+k++  H k+
  EEA19764.1 319 FECVVCNKLFKSQKQFEAHEKS 340
                 89*****************997 PP

  == domain 2  score: 16.2 bits;  conditional E-value: 6.7e-06
   zf-C2H2_4   2 kCpiCgksFsskkaLlrHlk 21 
                 kC++C++ Fss+++L +Hl+
  EEA19764.1 484 KCTHCQAMFSSRTQLFSHLR 503
                 8*****************98 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   1.1   2.3e-05     0.046       1      22 [.     319     340 ..     319     343 .. 0.90
   2 !   14.0   1.8   2.6e-05     0.052       2      23 .]     484     507 ..     484     507 .. 0.91

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 2.3e-05
                 EEETTTTEEESSHHHHHHHHHC CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirt 22 
                 ++C +C+k Fk++ ++++H ++
  EEA19764.1 319 FECVVCNKLFKSQKQFEAHEKS 340
                 89*****************886 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 2.6e-05
                 EETTTTEEESSHHHHHHHHHC..C CS
     zf-C2H2   2 kCpdCgksFkrksnLkrHirt..H 23 
                 kC++C  +F+++ +L +H+r   H
  EEA19764.1 484 KCTHCQAMFSSRTQLFSHLREigH 507
                 7******************97555 PP

>> RPT  A repeated domain in UCH-protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   5.2e-05       0.1       6      32 ..      25      52 ..      25      60 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 5.2e-05
         RPT  6 yklLgidentdDdviitayqvkl.eddp 32
                y+lLg+++++ Dd+i +ay+ k  e +p
  EEA19764.1 25 YELLGVERDAADDEIKKAYRRKAlELHP 52
                99******************99744344 PP

>> zf-C2H2_6  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   3.4   2.3e-05     0.046       1      24 [.     318     341 ..     318     344 .. 0.89
   2 ?    4.1   1.3     0.025        49       3      22 ..     484     503 ..     484     507 .. 0.94

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 2.3e-05
   zf-C2H2_6   1 vheCsvCsksFpslqaLggHkksH 24 
                 ++eC vC+k F+s++  + H ks 
  EEA19764.1 318 HFECVVCNKLFKSQKQFEAHEKSK 341
                 79*************999999884 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.025
   zf-C2H2_6   3 eCsvCsksFpslqaLggHkk 22 
                 +C+ C + F+s + L  H++
  EEA19764.1 484 KCTHCQAMFSSRTQLFSHLR 503
                 7*****************98 PP

>> LIM  LIM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.8   0.00068       1.3      25      46 ..     317     339 ..     315     344 .. 0.80
   2 ?    0.5   0.2      0.37   7.4e+02      28      41 ..     484     498 ..     483     504 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00068
                 TTSB-TTT-SB-CTT..CEEETT CS
         LIM  25 eCFtCsdCqkeLkegs.fyekdg 46 
                 e+F C +C+k +k+++ f  +++
  EEA19764.1 317 EHFECVVCNKLFKSQKqFEAHEK 339
                 8*************995544444 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.37
                 B-TTT-SB-CTT..C CS
         LIM  28 tCsdCqkeLkegs.f 41 
                 +C++Cq  +++++ +
  EEA19764.1 484 KCTHCQAMFSSRTqL 498
                 699999999988754 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (522 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1982  (0.110547); expected 358.6 (0.02)
Passed bias filter:                      664  (0.037035); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.64u 0.28s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 3506.97
//
Query:       EEA19765.1  [L=578]
Description: F-box only protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.2e-29  100.9   0.1    1.1e-28   99.7   0.1    1.7  1  YccV-like        Hemimethylated DNA-binding protein YccV like
    5.4e-16   58.5   0.0      1e-15   57.7   0.0    1.5  1  Transglut_core2  Transglutaminase-like superfamily
    5.5e-10   39.0   1.2    1.1e-09   38.0   1.2    1.6  1  F-box-like       F-box-like
    4.2e-07   30.4   0.3    8.7e-07   29.4   0.3    1.5  1  Elongin_A        RNA polymerase II transcription factor SIII 
    7.8e-07   28.8   0.2    1.8e-06   27.6   0.2    1.7  1  F-box            F-box domain
  ------ inclusion threshold ------
        0.1   12.6   2.3        3.6    7.6   2.3    2.6  1  F-box-like_2     F-box-like domain


Domain annotation for each model (and alignments):
>> YccV-like  Hemimethylated DNA-binding protein YccV like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.7   0.1   3.5e-32   1.1e-28       1      97 [.     468     563 ..     468     564 .. 0.92

  Alignments for each domain:
  == domain 1  score: 99.7 bits;  conditional E-value: 3.5e-32
   YccV-like   1 vkyrvGqvvrhkrygyrGVivgwdeecaaseewiekigveelsegrnqpfYhvlvdtedsekvsvrYvaeenlelikssep.....iehpeigkyFkrf 94 
                 vkyrvGqv+ h+ry+y+++i+gwd+ec+a+eew++++g+++l++gr+q+fYh l  +ed+   s+rYvaeenl++i+++ +     +    +gk+Fkr+
  EEA19765.1 468 VKYRVGQVFIHRRYDYQAIITGWDAECDAGEEWVRRMGIDQLQAGRKQSFYHAL--VEDR---SIRYVAEENLQIITPTMSdlssrLL-AIAGKHFKRW 560
                 79****************************************************..7777...689***********98889888544.459******* PP

   YccV-like  95 dga 97 
                 d++
  EEA19765.1 561 DED 563
                 985 PP

>> Transglut_core2  Transglutaminase-like superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.7   0.0   3.3e-19     1e-15       2     153 ..     190     359 ..     189     361 .. 0.83

  Alignments for each domain:
  == domain 1  score: 57.7 bits;  conditional E-value: 3.3e-19
  Transglut_core2   2 avlaeLdalaaevrae...lsseraaaekleaLnellyeelgFagned..dyydprnslldqVLerrr..GiPislsvvylevArrlglplegv 88 
                      +++++Ld++a+++ ++   ++s  ++++++  ++++l  +++++g +   +y+++++ +l   L+     ++P++ + +y+ +A+r+gl+++++
       EEA19765.1 190 DIRDMLDTIAENISQQvpdIRSL-TPRQRTVSIASYLL-THNYTGIRAgrEYHNLEHNFLGLALRDQGhnSLPLISATIYCAIAQRFGLNAQPC 281
                      6889************5543333.44445555666654.66666655444**************986555************************ PP

  Transglut_core2  89 gfPghflvrvg..............espegevliDPfnaGrllskedleellraalgaeaeltreflapasnrdvltRl 153
                      gfP h+lv +                +p+ ++++DP+ +   + ++dl++ l+ ++ a++  +++fl + s +d++ R+
       EEA19765.1 282 GFPFHVLVIILpavgfdldgreildGNPGSPMYMDPWRSDIEVPVADLQRQLNMYG-AQMVSQSQFLGKTSMSDIVWRC 359
                      *********9999999999998887777788*******999***********7775.5599*************99885 PP

>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.0   1.2   3.8e-13   1.1e-09       2      47 ..       6      50 ..       5      51 .. 0.92

  Alignments for each domain:
  == domain 1  score: 38.0 bits;  conditional E-value: 3.8e-13
  F-box-like  2 srLPdEiLlqIFsyLppsdLlrlalVCrrWrrvaldtplLWrrlvl 47
                ++LPdEiL  I+++ +p + l+l ++Crr+r +++  plLWr+ + 
  EEA19765.1  6 DDLPDEILHLILHHSEPAQCLALERTCRRFRGITNE-PLLWRHYCQ 50
                79***********999999**************965.5*****996 PP

>> Elongin_A  RNA polymerase II transcription factor SIII (Elongin) subunit A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.4   0.3   2.9e-10   8.7e-07       3      73 ..       4      81 ..       3      86 .. 0.88

  Alignments for each domain:
  == domain 1  score: 29.4 bits;  conditional E-value: 2.9e-10
   Elongin_A  3 dvGdvpyellrpiLekctpeqLreiEensphlaeetde..lWkklikrdfpeeskekste..pkep.....kswrelYek 73
                +++d+p e+l  iL++ +p q   +E  + ++ + t+e  lW++ ++  f+ +++++++e     +       w+elY +
  EEA19765.1  4 SLDDLPDEILHLILHHSEPAQCLALERTCRRFRGITNEplLWRHYCQSRFQYWDEKHNIEekL--RappstVGWKELYAE 81
                5799*****************************9999888******************99550..34455589*****86 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.6   0.2   6.1e-10   1.8e-06       2      47 ..       4      49 ..       3      50 .. 0.96

  Alignments for each domain:
  == domain 1  score: 27.6 bits;  conditional E-value: 6.1e-10
                HHHHS-HHHHHHHHHTS-HHHHHHHCTT-HHHHHHHTTHHHHHHHH CS
       F-box  2 tlsrLPsevlrhILerLplsdllalrrVSkgwrilidsdrlwcksi 47
                +l++LP+e+l+ IL + ++   lal r+++++r +++++ lw++++
  EEA19765.1  4 SLDDLPDEILHLILHHSEPAQCLALERTCRRFRGITNEPLLWRHYC 49
                689****************************************988 PP

>> F-box-like_2  F-box-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   2.3    0.0012       3.6      20      44 ..       3      27 ..       1      69 [. 0.64

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0012
  F-box-like_2 20 ltllDlPdellelifkgCkdpayep 44
                  ++l DlPde+l+li+++   ++  +
    EEA19765.1  3 ASLDDLPDEILHLILHHSEPAQCLA 27
                  5788**********99987443333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (578 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       393  (0.0219198); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.48
# Mc/sec: 3616.61
//
Query:       EEA19766.1  [L=299]
Description: C-4 methyl sterol oxidase Erg25, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.9e-25   89.1  17.3    2.9e-25   89.1  17.3    2.2  2  FA_hydroxylase  Fatty acid hydroxylase superfamily


Domain annotation for each model (and alignments):
>> FA_hydroxylase  Fatty acid hydroxylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.6      0.15   2.8e+03      48      48 ..      40      40 ..      12      83 .. 0.52
   2 !   89.1  17.3   1.6e-29   2.9e-25       2     133 .]     140     276 ..     139     276 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.15
  FA_hydroxylase 48 h 48
                     
      EEA19766.1 40 F 40
                    1 PP

  == domain 2  score: 89.1 bits;  conditional E-value: 1.6e-29
  FA_hydroxylase   2 llallledfveYwvHrllHrvkllwrrlHkvHHsseaptalaalrahpleallla.lllllll...lllg..plsalllvlvlaallelliHsgl 90 
                     ++++++ed+++Y+ Hr+lH+ + l++ +Hk+HH+++ap  laa++a+p+e++ll+  ++  ++   ++ g  ++ ++++++vl+ ++++  Hsg 
      EEA19766.1 140 AIFFVMEDTWHYFSHRALHWGP-LYKAIHKIHHQYSAPFGLAAEYASPIEVMLLGfGTVGCPIvwcAFTGdlHILTMYIWIVLRLFQAIDAHSG- 232
                     789****************865.9******************************9655554442225555788888888***************. PP

  FA_hydroxylase  91 hvslgwllerl...latpraHrlHHskneegnfgvllslwDrlfgT 133
                      ++++w l+++    a++ +H++HH+k+  gnf++++++wD+++ T
      EEA19766.1 233 -YEFPWSLHHFlpfWAGADHHDVHHEKFI-GNFASSFRWWDYVLDT 276
                     .999999955545569*************.************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (299 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       512  (0.0285571); expected 358.6 (0.02)
Passed bias filter:                      297  (0.0165653); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2115.00
//
Query:       EEA19767.1  [L=320]
Description: C-4 methyl sterol oxidase Erg25, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.4e-25   88.9  17.3    3.4e-25   88.9  17.3    2.4  3  FA_hydroxylase  Fatty acid hydroxylase superfamily


Domain annotation for each model (and alignments):
>> FA_hydroxylase  Fatty acid hydroxylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.1     0.094   1.7e+03      92     121 ..      18      47 ..       6      60 .. 0.61
   2 ?   -1.1   0.5      0.13   2.3e+03      42      42 ..      55      55 ..      21      99 .. 0.57
   3 !   88.9  17.3   1.9e-29   3.4e-25       2     133 .]     161     297 ..     160     297 .. 0.87

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.094
  FA_hydroxylase  92 vslgwllerllatpraHrlHHskneegnfg 121
                      sl++ + ++++tp++ + H ++  ++n +
      EEA19767.1  18 NSLDRNSTLFSTTPETYWSHFEEISKYNVH 47 
                     455555567778888888888777755433 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.13
  FA_hydroxylase 42 l 42
                    +
      EEA19767.1 55 W 55
                    1 PP

  == domain 3  score: 88.9 bits;  conditional E-value: 1.9e-29
  FA_hydroxylase   2 llallledfveYwvHrllHrvkllwrrlHkvHHsseaptalaalrahpleallla.lllllll...lllg..plsalllvlvlaallelliHsgl 90 
                     ++++++ed+++Y+ Hr+lH+ + l++ +Hk+HH+++ap  laa++a+p+e++ll+  ++  ++   ++ g  ++ ++++++vl+ ++++  Hsg 
      EEA19767.1 161 AIFFVMEDTWHYFSHRALHWGP-LYKAIHKIHHQYSAPFGLAAEYASPIEVMLLGfGTVGCPIvwcAFTGdlHILTMYIWIVLRLFQAIDAHSG- 253
                     789****************865.9******************************9655554442225555788888888***************. PP

  FA_hydroxylase  91 hvslgwllerl...latpraHrlHHskneegnfgvllslwDrlfgT 133
                      ++++w l+++    a++ +H++HH+k+  gnf++++++wD+++ T
      EEA19767.1 254 -YEFPWSLHHFlpfWAGADHHDVHHEKFI-GNFASSFRWWDYVLDT 297
                     .999999955545569*************.************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (320 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       583  (0.0325172); expected 358.6 (0.02)
Passed bias filter:                      349  (0.0194657); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.47
# Mc/sec: 2066.76
//
Query:       EEA19768.1  [L=216]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.8e-13   50.3   0.1    3.3e-13   49.5   0.1    1.4  1  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
    1.3e-05   24.9   0.1    4.2e-05   23.2   0.1    1.9  1  HTH_psq      helix-turn-helix, Psq domain
     0.0009   19.3   0.2     0.0051   16.9   0.1    2.3  2  HTH_28       Helix-turn-helix domain
     0.0031   17.5   0.6       0.31   11.1   0.1    3.0  3  HTH_29       Winged helix-turn helix
  ------ inclusion threshold ------
      0.019   15.0   0.2      0.038   14.0   0.2    1.5  1  DUF2089      Protein of unknown function (DUF2089)
      0.022   14.6   0.3       0.61   10.0   0.1    2.5  2  HTH_23       Homeodomain-like domain
        0.5   10.6   2.7         18    5.6   0.8    2.8  2  HTH_17       Helix-turn-helix domain


Domain annotation for each model (and alignments):
>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.5   0.1   1.3e-16   3.3e-13       2      63 ..      70     127 ..      69     130 .. 0.89

  Alignments for each domain:
  == domain 1  score: 49.5 bits;  conditional E-value: 1.3e-16
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT.S-- CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh.glk 63 
                  +++E++L++Wi +l++rg p++ +l++++A+ l s+      +d ++S++W++rF +Rh ++k
   EEA19768.1  70 QYEEESLQKWILDLDKRGLPPRPSLVQDMANLLVSQ-----REDEHVSEKWVYRFVNRHpEVK 127
                  679*****************************9633.....5899**************5555 PP

>> HTH_psq  helix-turn-helix, Psq domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.2   0.1   1.6e-08   4.2e-05       2      40 ..      16      55 ..      15      58 .. 0.89

  Alignments for each domain:
  == domain 1  score: 23.2 bits;  conditional E-value: 1.6e-08
     HTH_psq  2 pealaaAleavvnGk.mSirkAArkYgiPrsTLwrrkrgk 40
                + ++ +A+ +  +G   Sir+A r+Y+++++TL+rr+ g+
  EEA19768.1 16 EGKMLLAISDLKKGRiKSIREAVRIYNVSYTTLRRRLAGI 55
                67889999999999988*******************9887 PP

>> HTH_28  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.1     2e-06    0.0051       5      33 ..      22      52 ..      20      56 .. 0.90
   2 ?   -1.8   0.0       1.4   3.6e+03      13      25 ..     150     165 ..     145     167 .. 0.68

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 2e-06
      HTH_28  5 iikllaaGh..svreaArelgisrrtvyrWi 33
                +i  l++G+  s+rea r++++s++t++r +
  EEA19768.1 22 AISDLKKGRikSIREAVRIYNVSYTTLRRRL 52
                78889999999*****************987 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 1.4
      HTH_28  13 h..svreaArelgi.s 25 
                 h  +v +a +e+gi s
  EEA19768.1 150 HfdRVQAAIQEYGIlS 165
                 4457888888888855 PP

>> HTH_29  Winged helix-turn helix
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.1   0.1   0.00012      0.31       3      31 ..      21      50 ..      19      53 .. 0.86
   2 ?   -1.2   0.0      0.82   2.1e+03      20      40 ..      67      87 ..      57      93 .. 0.72
   3 ?    2.9   0.0     0.043   1.1e+02      24      35 ..     111     122 ..     110     127 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00012
      HTH_29  3 qallllaeGvs.tvsqiAkllglsrrtvyr 31
                +a+  l++G   +++++++++++s++t +r
  EEA19768.1 21 LAISDLKKGRIkSIREAVRIYNVSYTTLRR 50
                5677778877789***************99 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.82
      HTH_29 20 kllglsrrtvyrwlkrfeegG 40
                k++++ + + ++w+ + ++ G
  EEA19768.1 67 KMTQYEEESLQKWILDLDKRG 87
                677777777788887777766 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.043
      HTH_29  24 lsrrtvyrwlkr 35 
                 +s+++vyr+++r
  EEA19768.1 111 VSEKWVYRFVNR 122
                 79********98 PP

>> DUF2089  Protein of unknown function (DUF2089)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.2   1.5e-05     0.038      48      97 ..      27      82 ..       7      89 .. 0.68

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1.5e-05
     DUF2089 48 arGnlkevek...elgisYpTvrnrldeileaLgyeeeeeee.e.e.eeerkeile 97
                ++G++k++ +     ++sY+T+r rl  i  + + ++++++  + e e+ +k il+
  EEA19768.1 27 KKGRIKSIREavrIYNVSYTTLRRRLAGIEYRAEKRANSHKMtQyEeESLQKWILD 82
                57888877651115689************998888877664433222444555554 PP

>> HTH_23  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.1   0.00024      0.61      17      38 ..      31      52 ..      18      61 .. 0.81
   2 ?    2.1   0.0     0.072   1.8e+02      28      40 ..     110     122 ..     107     125 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00024
      HTH_23 17 GlsvreIAreLgvsrrTvyrwl 38
                 +s+re+ r+++vs+ T++r l
  EEA19768.1 31 IKSIREAVRIYNVSYTTLRRRL 52
                589****************965 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.072
      HTH_23  28 gvsrrTvyrwlkr 40 
                 +vs+ +vyr ++r
  EEA19768.1 110 HVSEKWVYRFVNR 122
                 89*******9988 PP

>> HTH_17  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.8     0.007        18       3      46 ..      33      79 ..      33      83 .. 0.62
   2 ?    3.8   0.0     0.026        66      13      25 ..     111     123 ..     110     138 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.007
      HTH_17  3 tveEaAelLgvsrstvyr.li.....rrgelpaakiGrrwriprsdleew 46
                ++ Ea ++ +vs +t++r l+      +++   +k      + +++l++w
  EEA19768.1 33 SIREAVRIYNVSYTTLRRrLAgieyrAEKRANSHKM---TQYEEESLQKW 79
                689**************6144333332333333333...55666666666 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.026
      HTH_17  13 vsrstvyrlirrg 25 
                 vs++ vyr+++r+
  EEA19768.1 111 VSEKWVYRFVNRH 123
                 9*********998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (216 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       641  (0.0357521); expected 358.6 (0.02)
Passed bias filter:                      458  (0.0255452); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.46
# Mc/sec: 1418.40
//
Query:       EEA19769.1  [L=326]
Description: aspergillopepsin A precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.1e-33  115.1   0.0    5.2e-33  114.8   0.0    1.1  1  Asp             Eukaryotic aspartyl protease
    0.00097   19.7   0.1        1.5    9.5   0.0    2.8  3  Asp_protease_2  Aspartyl protease
  ------ inclusion threshold ------
       0.18   12.0   0.1          7    6.8   0.1    2.8  3  TAXi_N          Xylanase inhibitor N-terminal


Domain annotation for each model (and alignments):
>> Asp  Eukaryotic aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.8   0.0   8.7e-37   5.2e-33       2     228 ..      84     306 ..      83     314 .. 0.89

  Alignments for each domain:
  == domain 1  score: 114.8 bits;  conditional E-value: 8.7e-37
                 EEEEEEETTTTEEEEEEEETT--SEEEEBTTESTSHCHHTSS-B-GGG-TT-EEEEEEEEEECTTS.EEEEEEEEEEEEETTEEEEEEEEEEEEE.ESS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxx RF
         Asp   2 YfgeisiGtpeqkftvifDTGSsdlWVpsskckkssackshstydpskSstykkngkslsisYGdg.svsGflsqdtvkvggltvknqefgeatk.epg 98 
                 Y+++i+iG     ++v++DTGS++lW    ++     + +h ty+ +  +     g+++s   G++  ++G ++ d++k+g l+ + q+++ +++ ep+
  EEA19769.1  84 YLTPIQIGAD--ILQVTLDTGSANLWGYTAQTP---CVGFHATYNTQ--TGILMPGYHWSTINGNQiILKGRVFLDKIKLGHLSFPYQAVQVVDTiEPV 175
                 99******98..89************9888876...4689****987..566779****88889998************************99872455 PP

                 HHHT..TSSSSEEEE-S-GGGSCGG...SCCHHHHHHHTTSSSSSEEEEEE-STTSSEEEEEESSEEGGGEEEEEEEEEESS.TSSTEEEEEEEEETTE CS
                 xxxx..xxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx RF
         Asp  99 stfl..aakfdGiLGlgfkeisvee...atpvfdnlvsqglikepvfsvylnreeeeggeivfGgvDeskykGsltyvpvts.kgywqielesvtvggk 191
                 s +l  + + dGi+Gl+f++ ++ +   ++++fdn++    +++p+f+vyl   +++ g++ +G +D+skykG+l++  v+  +g w+i ++++++gg+
  EEA19769.1 176 SAMLdpYRRHDGIIGLAFSSRNTIQpiqQKTFFDNIKP--YLNSPLFAVYLK--HRAPGSYDLGWIDPSKYKGQLFWRVVDDsRGLWTIAVDGFSIGGD 270
                 5554224569**********999998888899***875..6**********5..9*************************986899************* PP

                 EEEEEEEEEEEEETTCSSEEEEHHHHHHHHHHHTTEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp 192 tvlcssgcqailDtGTsllalptsivekiakaigakk 228
                 ++ +s  + a +DtGT+l+ l++++v+++ k+i +++
  EEA19769.1 271 SS-SSIPFPATIDTGTTLVLLQEDVVREYYKKIPGSY 306
                 *9.999*************************998765 PP

>> Asp_protease_2  Aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0      0.93   5.6e+03      10      20 ..      95     105 ..      87     113 .. 0.78
   2 !    9.5   0.0   0.00026       1.5      45      90 .]     136     193 ..     117     193 .. 0.84
   3 !    7.0   0.0    0.0016       9.3       8      34 ..     275     301 ..     264     307 .. 0.80

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.93
  Asp_protease_2  10 vrfllDTGast 20 
                     +++ lDTG+ +
      EEA19769.1  95 LQVTLDTGSAN 105
                     477899*9975 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00026
  Asp_protease_2  45 sgagge..vkarlvrldslklggltlknvpalvld..........lgeeidglLGmdf 90 
                     s+++g+    + +v ld++klg l+++ +++ v+d          + +++dg++G+ f
      EEA19769.1 136 STINGNqiILKGRVFLDKIKLGHLSFPYQAVQVVDtiepvsamldPYRRHDGIIGLAF 193
                     577777323568899********************9988888865557889****876 PP

  == domain 3  score: 7.0 bits;  conditional E-value: 0.0016
  Asp_protease_2   8 kpvrfllDTGasttlispelaeklglk 34 
                      p+ + +DTG + +l+ ++++++   k
      EEA19769.1 275 IPFPATIDTGTTLVLLQEDVVREYYKK 301
                     488999**************9987665 PP

>> TAXi_N  Xylanase inhibitor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.1    0.0012         7       1      28 [.      84     109 ..      84     139 .. 0.76
   2 ?    0.5   0.0       0.1   6.2e+02     130     153 ..     183     206 ..     146     226 .. 0.84
   3 ?    0.4   0.0      0.11   6.5e+02      12      34 ..     275     297 ..     267     318 .. 0.78

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0012
      TAXi_N   1 YlvsisiGtppqplklvvDtGsdltWvq 28 
                 Yl+ i+iG     l++++DtGs  +W  
  EEA19769.1  84 YLTPIQIGAD--ILQVTLDTGSANLWGY 109
                 999999*998..88999*********43 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.1
      TAXi_N 130 agadGilGLGrgklSlvsqlaskg 153
                 ++ dGi+GL++++   ++ +++k+
  EEA19769.1 183 RRHDGIIGLAFSSRNTIQPIQQKT 206
                 4579*****999988877777664 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.11
      TAXi_N  12 qplklvvDtGsdltWvqCkpcka 34 
                  p+ +++DtG  l+ +q +  ++
  EEA19769.1 275 IPFPATIDTGTTLVLLQEDVVRE 297
                 58999*********999766655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (326 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       384  (0.0214178); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.24s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2341.64
//
Query:       EEA19770.1  [L=182]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0025   18.5   0.1     0.0055   17.4   0.1    1.7  1  zf-RVT    zinc-binding in reverse transcriptase


Domain annotation for each model (and alignments):
>> zf-RVT  zinc-binding in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.1   3.1e-07    0.0055      51      80 ..      96     124 ..      66     127 .. 0.82

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 3.1e-07
      zf-RVT  51 lkrgiesssrCqlCgqeeEtieHlfleCpf 80 
                 + r  +++s  + Cgq+ Et+eH +++C++
  EEA19770.1  96 N-RIGAVDSDLCACGQASETVEHFLFRCTK 124
                 3.44445777789***************75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (182 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       541  (0.0301746); expected 358.6 (0.02)
Passed bias filter:                      381  (0.0212505); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.29s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1216.19
//
Query:       EEA19771.1  [L=506]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.9e-20   71.4   0.0    3.7e-19   69.0   0.0    2.1  2  DDE_1          DDE superfamily endonuclease
    6.7e-15   54.9   1.0    7.5e-14   51.5   0.0    2.8  3  HTH_Tnp_Tc5    Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
      0.025   14.7   1.3       0.21   11.7   0.6    2.5  2  Med9           RNA polymerase II transcription mediator compl
      0.059   12.9   0.0       0.19   11.3   0.0    1.9  1  HTH_24         Winged helix-turn-helix DNA-binding
       0.12   12.2   0.0       0.29   11.0   0.0    1.7  1  LexA_DNA_bind  LexA DNA binding domain


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.0   0.0     1e-22   3.7e-19       2     174 ..     203     370 ..     202     371 .. 0.88
   2 ?   -1.0   0.0      0.34   1.2e+03     119     168 ..     449     496 ..     443     501 .. 0.78

  Alignments for each domain:
  == domain 1  score: 69.0 bits;  conditional E-value: 1e-22
       DDE_1   2 erltvllcanaagsekLkplvigkaksprafkngektkkkldveyksnrkawltssifeeWLkvfdkrle..aekrkilLlldssrshetvel.lesel 97 
                 ++l+ +++ ++a+++k++p++i+ +k + ++++  k  k+ d+ +++ +k+   ++i  eWL++fdk ++  a ++  lL +d++++h t e+ + +++
  EEA19771.1 203 RELVSTIEGISATGNKIPPMLIFTGKAILESWF--KYLKEEDWLITIGDKGYSNDTIAYEWLQHFDKHTReqAGNNFRLLFMDNHDAHITSEFlSYCDK 299
                 5788999**************************..999********************************98889999***************99**** PP

       DDE_1  98 qniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksa 174
                  +i ++ +P++++++lqPld   + + K+  rr+++ ++  +    +k        d+l++i++ +  a++++ i+++
  EEA19771.1 300 YKILAIAFPPHTTHILQPLDGLPFMQYKRIHRRAINDQAHLGGYFYDK-------IDFLANIARVRAeALTPRVIRNG 370
                 ********************9999999999999888777665555555.......66666666666656666666665 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.34
       DDE_1 119 gvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwnavsk 168
                 g+   lK+ +   l qa ++ q++ +   ++l+ l+a k  kk+  +v++
  EEA19771.1 449 GIRRSLKKIFDGSLTQADIKDQQQAQI--ERLQTLNARKSAKKSKRQVQV 496
                 566778888888888888887776665..788889999999998888775 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.5   0.0   2.1e-17   7.5e-14       2      61 ..      64     123 ..      63     130 .. 0.93
   2 ?   -3.3   0.0       2.7   9.7e+03       9      25 ..     148     166 ..     146     168 .. 0.76
   3 ?    0.7   0.1      0.15   5.5e+02      28      56 ..     231     265 ..     225     269 .. 0.64

  Alignments for each domain:
  == domain 1  score: 51.5 bits;  conditional E-value: 2.1e-17
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHTS CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRhg 61 
                  +++E+a++ W+++l+ rgip++ ++i+++A++++++ + + ++ ++++ +W++rF+kR+g
   EEA19771.1  64 DDQERAIILWMNDLDDRGIPPSVRMIKNYAEKVHQNMHPNADSLPQLGDRWVYRFLKRLG 123
                  79********************************88899999****************94 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 2.7
                  HHHHHHH..C-CT---SCH CS
  HTH_Tnp_Tc5   9 leWirql..rergipitge 25 
                  + W+ +l  + +++ it +
   EEA19771.1 148 QTWFDRLeiAIQNYKITPS 166
                  5799988888888888865 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 0.15
                  HHHHHHHH......HHSSSCT-TT-S--CHHHHHH CS
  HTH_Tnp_Tc5  28 rekAqela......slaadlgepdfkaSkgWldrF 56 
                   e + +++       ++ d+g+++ +  ++Wl++F
   EEA19771.1 231 LESWFKYLkeedwlITIGDKGYSNDTIAYEWLQHF 265
                  55555555544445445777888888888899988 PP

>> Med9  RNA polymerase II transcription mediator complex subunit 9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0      0.28     1e+03      37      51 ..     201     215 ..     200     218 .. 0.87
   2 ?   11.7   0.6   5.7e-05      0.21      18      70 ..     430     486 ..     408     490 .. 0.80

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.28
        Med9  37 karelirelpgidrs 51 
                 + rel+++++gi+ +
  EEA19771.1 201 SSRELVSTIEGISAT 215
                 679*********987 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 5.7e-05
        Med9  18 nlsskdletktgelrhkLkkarelirelpgidrs....veeqeaeieeleeqlakKr 70 
                 ++s+k+++t+++e+ + +  +r  ++++ + + +    +++q+a+ie l+  +a+K 
  EEA19771.1 430 QRSIKKVDTQLNEISDAIPGIRRSLKKIFDGSLTqadiKDQQQAQIERLQTLNARKS 486
                 6999************************9966552233689999****999999886 PP

>> HTH_24  Winged helix-turn-helix DNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   5.4e-05      0.19       9      38 ..      17      46 ..      11      47 .. 0.94

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 5.4e-05
      HTH_24  9 LelLqknprisqreLAerlglSpstvnrrl 38
                Le+L+knp+  ++ LA++ g+  + ++rr+
  EEA19771.1 17 LEILRKNPKQKIKPLARQFGVDYQRLRRRV 46
                9************************99997 PP

>> LexA_DNA_bind  LexA DNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0     8e-05      0.29       2      32 ..      60      90 ..      59      94 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 8e-05
                   X---HHHHHHHHHHHHHHHHHSS---HHHHH CS
  LexA_DNA_bind  2 kkLTerQrevldlikasieetgypPsireia 32
                   k LT+ Q++ + l  + ++++g pPs+r i 
     EEA19771.1 60 KRLTDDQERAIILWMNDLDDRGIPPSVRMIK 90
                   689****9988888899***********986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (506 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       954  (0.0532099); expected 358.6 (0.02)
Passed bias filter:                      692  (0.0385967); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.45
# Mc/sec: 3342.41
//
Query:       EEA19772.1  [L=497]
Description: pogo transposable element, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.8e-27   95.0   0.0    5.9e-27   94.4   0.0    1.3  1  DDE_1        DDE superfamily endonuclease
    1.6e-12   47.3   0.0    5.8e-12   45.5   0.0    2.1  1  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
    0.00034   20.3   0.1    0.00097   18.8   0.0    1.8  2  HTH_psq      helix-turn-helix, Psq domain
  ------ inclusion threshold ------
      0.035   13.9   0.0       0.18   11.5   0.0    2.0  2  DDE_3        DDE superfamily endonuclease
      0.093   12.5   0.3       0.29   10.9   0.2    1.9  2  HTH_DeoR     DeoR-like helix-turn-helix domain


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.4   0.0   1.7e-30   5.9e-27       2     134 ..     205     340 ..     204     371 .. 0.95

  Alignments for each domain:
  == domain 1  score: 94.4 bits;  conditional E-value: 1.7e-30
       DDE_1   2 erltvllcanaagsekLkplvigkaksprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrle..aekrkilLlldssrshetvel.lese 96 
                 ++++++++++ + s   +pl+i+k+ + +a ++ +    + d++++ + k+w+ ++++ +WL k+f++ ++   ++ + lL+ld++ sh t e+   +e
  EEA19772.1 205 REWVTVVECVGSSSIIVPPLIIFKSRHNQAEWY-TDPILPPDWSITHSPKGWTFDELGLQWLeKIFEPFTRplTVGAYRLLILDGHSSHLTPEFdRACE 302
                 78999****************************.99999************************************************************ PP

       DDE_1  97 lqniklvflPassasllqPldqgvvselKarYrrqllq 134
                 ++ni + +lPa+s+ +lqPld+gv+s lK+ Y  ++ +
  EEA19772.1 303 KSNIITCCLPAHSSYILQPLDVGVFSVLKRLYGTAVEN 340
                 ********************************988766 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.5   0.0   1.6e-15   5.8e-12       2      63 ..      67     128 ..      66     131 .. 0.92

  Alignments for each domain:
  == domain 1  score: 45.5 bits;  conditional E-value: 1.6e-15
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT.S-- CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh.glk 63 
                  p +E aL++Wi  l +rg p+++e+ re+A+ l+ + +d+++p++k++ +W+d F++R+ +lk
   EEA19772.1  67 PTEEIALRNWILSLERRGLPPRREMAREMANVLLAE-RDKTKPPKKVGINWIDSFLSRNpDLK 128
                  78999***************************9966.8999*****************97776 PP

>> HTH_psq  helix-turn-helix, Psq domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.0   2.7e-07   0.00097       5      44 ..      16      56 ..      13      57 .. 0.88
   2 ?   -2.7   0.0       1.4     5e+03       8      24 ..     435     452 ..     433     453 .. 0.84

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 2.7e-07
     HTH_psq  5 laaAleavvnGk.mSirkAArkYgiPrsTLwrrkrgkyslk 44
                +++ ++av n+k  +ir+ Ar+++++  TL++r++g++++k
  EEA19772.1 16 ISLSIDAVKNKKtKTIRQTARLFDVSEATLRNRLKGGITSK 56
                56668999999988**********************99876 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 1.4
     HTH_psq   8 AleavvnGk.mSirkAAr 24 
                 Al+  ++G+ ++++ AA 
  EEA19772.1 435 ALDQLLKGAlITMHNAAI 452
                 8888999*9999999995 PP

>> DDE_3  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0      0.34   1.2e+03       2      44 ..     169     214 ..     168     236 .. 0.76
   2 ?   11.5   0.0     5e-05      0.18      65     117 ..     262     316 ..     256     332 .. 0.91

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.34
       DDE_3   2 vvfiDEsgfqlgt.vrrrawakkGkr.er.leeygrrgrvnligal 44 
                 ++ +DE+gf  g    ++  +  +++ +  + + g+r+ v+++  +
  EEA19772.1 169 IYNFDETGFAMGIgATAKVIYSSDRQgKPsIIQPGNREWVTVVECV 214
                 6778999999888888888888888874458888888888887655 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 5e-05
       DDE_3  65 aeflerlletalqak....kivlilDnasiHkseslrelveeeadrlellylPpySP 117
                  ++le++ e+++++        lilD++s H   ++ ++ e+   ++ +  lP++S+
  EEA19772.1 262 LQWLEKIFEPFTRPLtvgaYRLLILDGHSSHLTPEFDRACEK--SNIITCCLPAHSS 316
                 5799999999999888888899********************..************8 PP

>> HTH_DeoR  DeoR-like helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.2     8e-05      0.29       6      33 ..      20      47 ..      15      51 .. 0.88
   2 ?   -4.0   0.0       3.8   1.4e+04      44      52 ..     330     338 ..     329     340 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 8e-05
    HTH_DeoR  6 lellkqqgklsveelvellgvSeaTiRR 33
                ++ +k++ + ++ + + l++vSeaT R+
  EEA19772.1 20 IDAVKNKKTKTIRQTARLFDVSEATLRN 47
                678999*********************7 PP

  == domain 2  score: -4.0 bits;  conditional E-value: 3.8
    HTH_DeoR  44 ltRthGGav 52 
                 l+R +G av
  EEA19772.1 330 LKRLYGTAV 338
                 89****886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (497 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       574  (0.0320152); expected 358.6 (0.02)
Passed bias filter:                      502  (0.0279993); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 3231.01
//
Query:       EEA19773.1  [L=359]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.9e-13   49.0   0.2    1.9e-12   47.6   0.0    1.9  2  RNase_H   RNase H
  ------ inclusion threshold ------
          2    8.2   6.8       0.14   11.8   1.2    2.1  2  DUF2934   Protein of unknown function (DUF2934)


Domain annotation for each model (and alignments):
>> RNase_H  RNase H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.6   0.0   2.1e-16   1.9e-12       3     143 .]      41     183 ..      39     183 .. 0.74
   2 ?   -3.1   0.1      0.91   8.2e+03     100     100 ..     227     227 ..     203     254 .. 0.42

  Alignments for each domain:
  == domain 1  score: 47.6 bits;  conditional E-value: 2.1e-16
                 SEEEEEEEEEECTTTCEEEEEEECTT...EEEEEEECCCCHHHHHHHHHHHHHHHTT.SC..............SEEEEEES-HHHHHHHHCCCHHHHH CS
     RNase_H   3 avvvYtDGsclgnpgeggagavlykeg.arnisapleeaqtnnraELsAvieaLkalksd..............ekvniytDSkYvvkgitqwvhrwkk 86 
                 ++ +YtDGs  g +g+ gag+v+++ g +r+ +  +++      aEL+ +++aL+a ++                 + iytD + ++k++ +       
  EEA19773.1  41 DIQIYTDGS--GHNGQIGAGMVVPGMGiTRKAYLGTTGSFLVYAAELRGIVMALEAIQQYsqqriararnrwlgRGIRIYTDNQAALKALIR------- 130
                 5789*****..779999999999977655566666667778899***********8765555667777776676777788888777775554....... PP

                 TTSSSETTSSBHTTHHHHHHHHHCHC.SSEEEEEE-SCCSSSTHHHHHHHHHHHHHHT CS
     RNase_H  87 nawkttseqkpvknkdlaellkelak.kkkvqlkwvkgHaGvpkgNemaDrlAkeaae 143
                    ++ +++ ++  +d  ++l+ + + + +v+++w++gH+Gv +gNe+aDr+Akeaae
  EEA19773.1 131 ---PRMASG-QIYLRDALKILTWCENnNITVSFHWIPGHEGV-EGNEAADRAAKEAAE 183
                 ...222333.25555777777444444778************.7***********985 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 0.91
                 T CS
     RNase_H 100 n 100
                  
  EEA19773.1 227 R 227
                 1 PP

>> DUF2934  Protein of unknown function (DUF2934)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.4       1.3   1.2e+04       9      18 ..     105     114 ..     104     114 .. 0.82
   2 ?   11.8   1.2   1.6e-05      0.14      15      32 ..     182     199 ..     172     201 .. 0.86

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 1.3
     DUF2934   9 rAYelWErrG 18 
                 rA  +W  rG
  EEA19773.1 105 RARNRWLGRG 114
                 8999998887 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 1.6e-05
     DUF2934  15 ErrGrpeGrdeedWleAE 32 
                  ++G+  Grd+ +Wl+A 
  EEA19773.1 182 AEQGYVQGRDHIHWLAAV 199
                 578**************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (359 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       491  (0.0273858); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.23s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2518.40
//
Query:       EEA19774.1  [L=551]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      1e-12   47.9   0.0    3.7e-12   46.1   0.0    2.0  1  HTH_Tnp_Tc5     Tc5 transposase DNA-binding domain
     0.0083   15.8   0.1       0.29   10.8   0.0    3.0  4  DDE_1           DDE superfamily endonuclease
      0.009   16.6   0.6      0.069   13.8   0.1    2.7  2  Tn7_Tnp_TnsA_C  TnsA endonuclease C terminal


Domain annotation for each model (and alignments):
>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.1   0.0   6.2e-16   3.7e-12       2      63 ..      64     125 ..      63     128 .. 0.92

  Alignments for each domain:
  == domain 1  score: 46.1 bits;  conditional E-value: 6.2e-16
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHTS-- CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRhglk 63 
                  +++E a++ Wi +l+ rg p+t ++ir++A+++ ++ + +   ++k++ +W++rF+kR++++
   EEA19774.1  64 DDQESAIIIWIDDLDDRGLPPTVHMIRNYAENVPQNMHPNAANHPKLGDRWVHRFLKRLPPA 125
                  79*******************************97778888999**************9875 PP

>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       0.8   4.8e+03      51      71 ..     103     123 ..      95     134 .. 0.73
   2 ?    1.3   0.0      0.04   2.4e+02       4      35 ..     206     236 ..     202     260 .. 0.67
   3 !   10.8   0.0   4.8e-05      0.29      84     135 ..     259     311 ..     258     333 .. 0.87
   4 ?   -2.2   0.1      0.48   2.9e+03     107     145 ..     423     449 ..     404     487 .. 0.47

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 0.8
       DDE_1  51 kawltssifeeWLkvfdkrle 71 
                 +a    +++ +W ++f krl 
  EEA19774.1 103 NAANHPKLGDRWVHRFLKRLP 123
                 666677889999999999876 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.04
       DDE_1   4 ltvllcanaagsekLkplvigkaksprafkng 35 
                 +tv+ + naag   ++p +i+ +k + ++++ 
  EEA19774.1 206 VTVIEGLNAAG-SAIPPFLIFTGKVILESWFQ 236
                 55555556665.579***********999992 PP

  == domain 3  score: 10.8 bits;  conditional E-value: 4.8e-05
       DDE_1  84 srshetvel.leselqniklvflPassasllqPldqgvvselKarYrrqllqa 135
                 +++h + e+   + +++i  + +Pa++++llqPld   + + K+  rr+++++
  EEA19774.1 259 HTAHLIREFmDYCLEHKIVPFRFPAHTTHLLQPLDGMPFLHYKRIHRRAINEQ 311
                 6789999998889999*******************998888888888887766 PP

  == domain 4  score: -2.2 bits;  conditional E-value: 0.48
       DDE_1 107 assasllqPldqgvvselKarYrrqllqalleeqnrlsk 145
                     sl + +d +              qa ++eq++ + 
  EEA19774.1 423 GIRRSLKKIFDGSL------------TQAHIKEQQQEQI 449
                 44444444444444............4444433333222 PP

>> Tn7_Tnp_TnsA_C  TnsA endonuclease C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.8   0.1   1.1e-05     0.069      25      60 ..       5      40 ..       2      47 .. 0.91
   2 ?   -1.4   0.0      0.66   3.9e+03      12      42 ..     114     142 ..     113     155 .. 0.58

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.1e-05
  Tn7_Tnp_TnsA_C 25 seeeleelaelllerlrenpdttlrellkelDkeys 60
                    +++e+e+++++ le+l++np++++ +l+ e+D +y+
      EEA19774.1  5 QYKEEESRIQKALESLQKNPKQKIAHLAREFDVDYH 40
                    567889***************************997 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.66
  Tn7_Tnp_TnsA_C  12 wlhpyrried..ddlseeeleelaelllerlre 42 
                     w+h++ ++ +  ++++    ++++  l ++l+e
      EEA19774.1 114 WVHRFLKRLPpaYKIQ----KQKTIDLKRHLAE 142
                     7777776533333333....4555555555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (551 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1215  (0.0677673); expected 358.6 (0.02)
Passed bias filter:                      623  (0.0347482); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.69u 0.32s 00:00:01.01 Elapsed: 00:00:00.51
# Mc/sec: 3253.53
//
Query:       EEA19775.1  [L=532]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      1e-13   50.6   0.0    3.1e-05   23.6   0.0    3.4  3  HTH_23          Homeodomain-like domain
    4.6e-13   49.6   8.5    5.9e-06   26.8   0.1    5.2  5  HTH_32          Homeodomain-like domain
    2.8e-11   43.5   0.1    5.7e-10   39.3   0.0    3.1  3  HTH_Tnp_Tc3_2   Transposase
    1.6e-07   31.2   0.0    5.1e-07   29.6   0.0    1.8  1  DDE_3           DDE superfamily endonuclease
    3.9e-07   29.6   1.0      0.038   13.7   0.1    2.9  3  Sigma70_r4_2    Sigma-70, region 4
    9.9e-07   28.8   2.3       0.12   12.6   0.0    4.0  4  HTH_28          Helix-turn-helix domain
    3.2e-06   26.9   0.6       0.17   11.8   0.0    3.0  3  TrmB            Sugar-specific transcriptional regulator TrmB
    4.2e-05   23.4   0.1       0.49   10.4   0.0    2.6  2  HRDC            HRDC domain
    0.00019   21.4   0.0        3.3    7.8   0.0    4.2  3  HTH_29          Winged helix-turn helix
     0.0034   17.6   0.8        3.7    7.9   0.1    2.5  2  KORA            TrfB plasmid transcriptional repressor
     0.0034   17.5   0.0        7.7    6.8   0.0    3.2  3  HTH_17          Helix-turn-helix domain
       0.01   16.0   1.9        3.2    8.0   0.3    2.7  2  DUF1492         Protein of unknown function (DUF1492)
  ------ inclusion threshold ------
      0.011   15.9   0.2        8.3    6.6   0.0    2.5  2  DUF2773         Protein of unknown function (DUF2773)
      0.014   15.1   4.5        2.5    7.8   0.1    3.2  4  DUF835          Protein of unknown function (DUF835)
      0.027   14.7   0.0         17    5.7   0.0    2.7  2  Fe_dep_repress  Iron dependent repressor, N-terminal DNA bind
      0.052   13.4   0.0         24    4.8   0.0    3.2  3  HTH_IclR        IclR helix-turn-helix domain
      0.077   13.0   0.0         27    4.8   0.0    3.1  3  HTH_Crp_2       Crp-like helix-turn-helix domain
      0.085   12.6   0.1         16    5.1   0.0    2.4  2  DUF1681         Protein of unknown function (DUF1681)
      0.089   12.3   2.7         14    5.3   0.1    3.3  3  Sigma70_r4      Sigma-70, region 4
      0.099   12.5   0.4         39    4.2   0.0    3.2  3  MarR_2          MarR family
       0.11   12.6   2.3         18    5.5   0.2    3.3  3  HTH_7           Helix-turn-helix domain of resolvase


Domain annotation for each model (and alignments):
>> HTH_23  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.6   0.0   3.6e-08   3.1e-05       3      48 ..       7      53 ..       5      55 .. 0.93
   2 !   22.7   0.0   6.9e-08   5.9e-05       4      48 ..     107     152 ..     104     154 .. 0.92
   3 ?   -1.1   0.0       2.2   1.9e+03      28      39 ..     206     217 ..     204     220 .. 0.88

  Alignments for each domain:
  == domain 1  score: 23.6 bits;  conditional E-value: 3.6e-08
      HTH_23  3 sereRlrillllae.GlsvreIAreLgvsrrTvyrwlkryreeGleg 48
                s++ R++i+ l+   ++ ++++A +L+++r  vy++++r +e+G ++
  EEA19775.1  7 SVETRAQIVALVMIaKMKPQDVAILLNIPRVSVYQIVQRAKEHGYDP 53
                7899*********88************************99999776 PP

  == domain 2  score: 22.7 bits;  conditional E-value: 6.9e-08
      HTH_23   4 ereRlrillllae.GlsvreIAreLgvsrrTvyrwlkryreeGleg 48 
                 ++ R++i+ l+   ++ ++++A +L+++r  vy++++r +e+G ++
  EEA19775.1 107 VETRAQIVALVMIaKMKPQDVAILLNIPRVSVYQIVQRAKEHGYDP 152
                 679*********88************************99999776 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 2.2
      HTH_23  28 gvsrrTvyrwlk 39 
                 g+s++ v r lk
  EEA19775.1 206 GISESSVLRLLK 217
                 9********998 PP

>> HTH_32  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0       2.9   2.5e+03      30      53 ..       7      29 ..       3      37 .. 0.74
   2 !   20.7   0.1   5.7e-07   0.00049       1      59 [.      38     105 ..      38     132 .. 0.90
   3 !   26.8   0.1   6.9e-09   5.9e-06       1      73 []     137     216 ..     137     216 .. 0.91
   4 ?    0.4   0.0       1.2   1.1e+03      26      54 ..     230     257 ..     223     271 .. 0.68
   5 ?    1.8   0.1      0.45   3.8e+02      14      28 ..     353     369 ..     339     380 .. 0.77

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 2.9
      HTH_32 30 sdevrariiallreeprWsprqla 53
                s e+ra+i+al+    ++ p+ +a
  EEA19775.1  7 SVETRAQIVALV-MIAKMKPQDVA 29
                6699******99.54466666666 PP

  == domain 2  score: 20.7 bits;  conditional E-value: 5.7e-07
      HTH_32   1 TvsrwlkRyneeGle.gLkdr.........prrgrprklsdevrariiallreeprWsprqlaarlaer 59 
                 +v+  ++R +e+G++  + +r          r+grp+ ++++ +a iia + ++ r + ++ a++la +
  EEA19775.1  38 SVYQIVQRAKEHGYDpTVNPRiehehvannTRSGRPKVVTEAIEASIIASI-TKDRAGREKSAEYLAYE 105
                 5999*************************9999******************.55599999999999444 PP

  == domain 3  score: 26.8 bits;  conditional E-value: 6.9e-09
      HTH_32   1 TvsrwlkRyneeGle.gLkdr.........prrgrprklsdevrariiallreeprWsprqlaarlaeregvkvShstvyriL 73 
                 +v+  ++R +e+G++  + +r          r+grp+ ++++ +a iia + ++ r + ++ a++la +    +S+s+v r+L
  EEA19775.1 137 SVYQIVQRAKEHGYDpTVNPRiehehvannTRSGRPKVVTEAIEASIIASI-TKDRAGREKSAEYLAYEA--GISESSVLRLL 216
                 5999*************************9999******************.5559**********4444..7******9987 PP

  == domain 4  score: 0.4 bits;  conditional E-value: 1.2
      HTH_32  26 prklsdevrariiallreeprWsprqlaa 54 
                 p  l+d  +++ +a + e+ +W+++    
  EEA19775.1 230 PG-LTDKMKQARLAFALEHQHWTLEDFKN 257
                 33.66666666666665888***998665 PP

  == domain 5  score: 1.8 bits;  conditional E-value: 0.45
      HTH_32  14 legLkdrprrgrpr..k 28 
                 ++ L+ rprrgr++  k
  EEA19775.1 353 FSRLQLRPRRGRKPnfK 369
                 567888999**998554 PP

>> HTH_Tnp_Tc3_2  Transposase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       2.8   2.4e+03      36      60 ..      40      64 ..      33      66 .. 0.74
   2 ?   -1.2   0.0       2.8   2.4e+03      36      60 ..     139     163 ..     132     165 .. 0.74
   3 !   39.3   0.0   6.6e-13   5.7e-10       4      72 .]     183     249 ..     180     249 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 2.8
  HTH_Tnp_Tc3_2 36 rrrLrkaglkkrkprkkplLskknr 60
                    ++ ++a+ +++ p+  p + ++++
     EEA19775.1 40 YQIVQRAKEHGYDPTVNPRIEHEHV 64
                   5566777778888999999888886 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 2.8
  HTH_Tnp_Tc3_2  36 rrrLrkaglkkrkprkkplLskknr 60 
                     ++ ++a+ +++ p+  p + ++++
     EEA19775.1 139 YQIVQRAKEHGYDPTVNPRIEHEHV 163
                    5566777778888999999888886 PP

  == domain 3  score: 39.3 bits;  conditional E-value: 6.6e-13
  HTH_Tnp_Tc3_2   4 IvrlvrkdPr...itlreLanelkeeGksvsreTirrrLrkaglkkrkprkkplLskknrkaRLeFAkehln 72 
                    I+  ++kd+    ++++ La e       +s + + r L+ + ++k+kp+ kp+L+ k+++aRL+FA+eh++
     EEA19775.1 183 IIASITKDRAgreKSAEYLAYEA-----GISESSVLRLLKLNSFNKCKPTVKPGLTDKMKQARLAFALEHQH 249
                    56666666655559999999999.....89****************************************85 PP

>> DDE_3  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.6   0.0     6e-10   5.1e-07      74     133 ..     391     448 ..     362     458 .. 0.86

  Alignments for each domain:
  == domain 1  score: 29.6 bits;  conditional E-value: 6e-10
       DDE_3  74 talqakkivlilDnasiHkseslrelveeeadrlellylPpySPelNpiEivwsklkrel 133
                 ++++  ++++  Dna+ H   + +e+ +   ++++ l +P +SP+lN iE  w +lk++ 
  EEA19775.1 391 CKRSRPGTIVMEDNAPAHAHFHQKEIYSF--HDVQRLPWPGNSPDLNAIEPTWFWLKKRT 448
                 333333899*****************999..**************************975 PP

>> Sigma70_r4_2  Sigma-70, region 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.7   0.1   4.5e-05     0.038      14      53 ..      10      49 ..       9      49 .. 0.93
   2 !   13.7   0.1   4.5e-05     0.038      14      53 ..     109     148 ..     108     148 .. 0.93
   3 ?   -2.7   0.0       5.7   4.9e+03      33      43 ..     198     212 ..     198     216 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 4.5e-05
                  HHHHHHHHHHTS---HHHHHHHHT--HHHHHHHHHHHHHH CS
  Sigma70_r4_2 14 rqreifllryleglsykEIAellgisegtVksrlsRArkk 53
                   + +i+ l  +  ++ +++A ll+i+ ++V++ ++RA+++
    EEA19775.1 10 TRAQIVALVMIAKMKPQDVAILLNIPRVSVYQIVQRAKEH 49
                  67899999999**************************986 PP

  == domain 2  score: 13.7 bits;  conditional E-value: 4.5e-05
                   HHHHHHHHHHTS---HHHHHHHHT--HHHHHHHHHHHHHH CS
  Sigma70_r4_2  14 rqreifllryleglsykEIAellgisegtVksrlsRArkk 53 
                    + +i+ l  +  ++ +++A ll+i+ ++V++ ++RA+++
    EEA19775.1 109 TRAQIVALVMIAKMKPQDVAILLNIPRVSVYQIVQRAKEH 148
                   67899999999**************************986 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 5.7
                   HHHH....T--HHHH CS
  Sigma70_r4_2  33 Aell....gisegtV 43 
                   Ae+l    gise++V
    EEA19775.1 198 AEYLayeaGISESSV 212
                   677777779***999 PP

>> HTH_28  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.0   0.00014      0.12       2      46 ..      11      56 ..      10      74 .. 0.80
   2 !   12.6   0.0   0.00014      0.12       2      46 ..     110     155 ..     109     173 .. 0.80
   3 ?    0.3   0.0      0.92   7.8e+02      14      34 ..     197     217 ..     189     219 .. 0.79
   4 ?   -2.9   0.8       9.1   7.7e+03      44      51 ..     358     365 ..     353     366 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 0.00014
      HTH_28  2 Rleiiklla.aGhsvreaArelgisrrtvyrWikryeegGiagLvp 46
                R++i+ l++ a +   ++A +l+i r +vy+ ++r  e+G +  v+
  EEA19775.1 11 RAQIVALVMiAKMKPQDVAILLNIPRVSVYQIVQRAKEHGYDPTVN 56
                99*****777******************************886665 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 0.00014
      HTH_28   2 Rleiiklla.aGhsvreaArelgisrrtvyrWikryeegGiagLvp 46 
                 R++i+ l++ a +   ++A +l+i r +vy+ ++r  e+G +  v+
  EEA19775.1 110 RAQIVALVMiAKMKPQDVAILLNIPRVSVYQIVQRAKEHGYDPTVN 155
                 99*****777******************************886665 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.92
      HTH_28  14 svreaArelgisrrtvyrWik 34 
                 s+  +A e gis+++v r++k
  EEA19775.1 197 SAEYLAYEAGISESSVLRLLK 217
                 666678889*******99998 PP

  == domain 4  score: -2.9 bits;  conditional E-value: 9.1
      HTH_28  44 Lvprrrrp 51 
                 L+prr+r+
  EEA19775.1 358 LRPRRGRK 365
                 78999987 PP

>> TrmB  Sugar-specific transcriptional regulator TrmB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   0.0    0.0002      0.17      15      50 ..      15      50 ..      13      52 .. 0.91
   2 !   11.8   0.0    0.0002      0.17      15      50 ..     114     149 ..     112     151 .. 0.91
   3 ?   -1.6   0.0         3   2.5e+03      23      43 ..     196     216 ..     194     217 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.0002
                HHHHHHCCCHHCHHCCCTTSSCHCHHHHHHHHHHCT CS
        TrmB 15 laLlklgpatadeiaeelgvprskvYevLrsLedkG 50
                +aL++  +++ +++a  l++pr +vY+++++ ++ G
  EEA19775.1 15 VALVMIAKMKPQDVAILLNIPRVSVYQIVQRAKEHG 50
                5899999**********************9977666 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 0.0002
                 HHHHHHCCCHHCHHCCCTTSSCHCHHHHHHHHHHCT CS
        TrmB  15 laLlklgpatadeiaeelgvprskvYevLrsLedkG 50 
                 +aL++  +++ +++a  l++pr +vY+++++ ++ G
  EEA19775.1 114 VALVMIAKMKPQDVAILLNIPRVSVYQIVQRAKEHG 149
                 5899999**********************9977666 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 3
                 CHHCHHCCCTTSSCHCHHHHH CS
        TrmB  23 atadeiaeelgvprskvYevL 43 
                 ++a+ +a e+g+++s+v + L
  EEA19775.1 196 KSAEYLAYEAGISESSVLRLL 216
                 678889999******998776 PP

>> HRDC  HRDC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.4   0.0   0.00058      0.49      31      61 ..      16      46 ..      12      48 .. 0.89
   2 !   10.4   0.0    0.0006      0.51      31      61 ..     115     145 ..     112     147 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00058
                HHHHHHHH---SHHHHHTSTTT-HHHHHHHH CS
        HRDC 31 tLleiAeklPttleeLlqiegvgkrklekyg 61
                +L++iA+ +P++++ Ll+i+ v+ +++ + +
  EEA19775.1 16 ALVMIAKMKPQDVAILLNIPRVSVYQIVQRA 46
                79*********************99987765 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.0006
                 HHHHHHHH---SHHHHHTSTTT-HHHHHHHH CS
        HRDC  31 tLleiAeklPttleeLlqiegvgkrklekyg 61 
                 +L++iA+ +P++++ Ll+i+ v+ +++ + +
  EEA19775.1 115 ALVMIAKMKPQDVAILLNIPRVSVYQIVQRA 145
                 79*********************99987765 PP

>> HTH_29  Winged helix-turn helix
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.8   0.0    0.0038       3.3       1      63 []      11      82 ..      11      82 .. 0.80
   2 !    7.8   0.0    0.0038       3.3       1      63 []     110     181 ..     110     181 .. 0.80
   3 ?   -0.9   0.0         2   1.7e+03      19      35 ..     202     218 ..     196     219 .. 0.87

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0038
      HTH_29  1 RaqallllaeGvstvsqiAkllglsrrtvyrwlkrfeegGlaa..........lldrrrsgrprnrlseeqea 63
                Raq+++l+  + + ++++A ll++ r +vy ++ r  e+G +             ++ rsgrp+ +++e+ ea
  EEA19775.1 11 RAQIVALVMIAKMKPQDVAILLNIPRVSVYQIVQRAKEHGYDPtvnpriehehVANNTRSGRPK-VVTEAIEA 82
                77778777777667999999********************888555566667766667789997.78888886 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0038
      HTH_29   1 RaqallllaeGvstvsqiAkllglsrrtvyrwlkrfeegGlaa..........lldrrrsgrprnrlseeqea 63 
                 Raq+++l+  + + ++++A ll++ r +vy ++ r  e+G +             ++ rsgrp+ +++e+ ea
  EEA19775.1 110 RAQIVALVMIAKMKPQDVAILLNIPRVSVYQIVQRAKEHGYDPtvnpriehehVANNTRSGRPK-VVTEAIEA 181
                 77778777777667999999********************888555566667766667789997.78888886 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 2
      HTH_29  19 Akllglsrrtvyrwlkr 35 
                 A   g+s+++v r lk+
  EEA19775.1 202 AYEAGISESSVLRLLKL 218
                 77789********9996 PP

>> KORA  TrfB plasmid transcriptional repressor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.5   0.1    0.0057       4.9      20      55 ..      11      46 ..       5      55 .. 0.91
   2 !    7.9   0.1    0.0044       3.7      19      55 ..     109     145 ..     100     154 .. 0.90

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0057
        KORA 20 tveiargvLVegkkqadvatelgltkqavsqavkrv 55
                  +i+  v++ + k +dva  l + +  v q+v+r+
  EEA19775.1 11 RAQIVALVMIAKMKPQDVAILLNIPRVSVYQIVQRA 46
                5699******************************97 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0044
        KORA  19 qtveiargvLVegkkqadvatelgltkqavsqavkrv 55 
                    +i+  v++ + k +dva  l + +  v q+v+r+
  EEA19775.1 109 TRAQIVALVMIAKMKPQDVAILLNIPRVSVYQIVQRA 145
                 4579*******************************97 PP

>> HTH_17  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.8   0.0     0.009       7.7       2      24 ..      23      45 ..      23      48 .. 0.90
   2 !    6.8   0.0     0.009       7.7       2      24 ..     122     144 ..     122     147 .. 0.90
   3 ?   -2.6   0.0       7.6   6.5e+03      14      27 ..     472     485 ..     470     492 .. 0.62

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.009
      HTH_17  2 ltveEaAelLgvsrstvyrlirr 24
                ++++++A lL++ r +vy+ ++r
  EEA19775.1 23 MKPQDVAILLNIPRVSVYQIVQR 45
                7899**************98875 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.009
      HTH_17   2 ltveEaAelLgvsrstvyrlirr 24 
                 ++++++A lL++ r +vy+ ++r
  EEA19775.1 122 MKPQDVAILLNIPRVSVYQIVQR 144
                 7899**************98875 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 7.6
      HTH_17  14 srstvyrlirrgel 27 
                  +++++ ++ r ++
  EEA19775.1 472 PQHHIQAWVERIPF 485
                 55666777766555 PP

>> DUF1492  Protein of unknown function (DUF1492)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.1     0.012        10      62      96 ..      13      47 ..       5      49 .. 0.88
   2 !    8.0   0.3    0.0037       3.2      32      96 ..      78     146 ..      74     148 .. 0.69

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.012
     DUF1492 62 svLrmvyidkltvwqvidklnisrstyyrllrvav 96
                 ++ +v i k++ ++v   lni r   y++ + a+
  EEA19775.1 13 QIVALVMIAKMKPQDVAILLNIPRVSVYQIVQRAK 47
                58899***********************9998886 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0037
     DUF1492  32 ediekktaeaikkklelqrlidk...lensdsrs.vLrmvyidkltvwqvidklnisrstyyrllrvav 96 
                 e+ie++    i k +  ++  ++    e  ++r+ ++ +v i k++ ++v   lni r   y++ + a+
  EEA19775.1  78 EAIEASIIASITKDRAGREKSAEylaYEAVETRAqIVALVMIAKMKPQDVAILLNIPRVSVYQIVQRAK 146
                 66666666666665544433322111345555543899************************9998886 PP

>> DUF2773  Protein of unknown function (DUF2773)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   0.0      0.01       8.6       8      40 ..      15      47 ..      10      62 .. 0.81
   2 ?    6.6   0.0    0.0097       8.3       8      40 ..     114     146 ..     108     161 .. 0.82

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.01
     DUF2773  8 PalllaaeiePedrilainnPrlavdvkkarlk 40
                 al++ a+++P+d  + +n Pr++v     r k
  EEA19775.1 15 VALVMIAKMKPQDVAILLNIPRVSVYQIVQRAK 47
                5899*******************9975555555 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0097
     DUF2773   8 PalllaaeiePedrilainnPrlavdvkkarlk 40 
                  al++ a+++P+d  + +n Pr++v     r k
  EEA19775.1 114 VALVMIAKMKPQDVAILLNIPRVSVYQIVQRAK 146
                 5899*******************9975555555 PP

>> DUF835  Protein of unknown function (DUF835)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.2     0.005       4.2      19      86 ..      14      81 ..       3      87 .. 0.81
   2 ?    7.8   0.1    0.0029       2.5      16      86 ..     110     180 ..      94     186 .. 0.78
   3 ?   -1.1   0.0       1.7   1.4e+03      36      70 ..     204     238 ..     194     241 .. 0.81
   4 ?   -2.4   0.0       4.4   3.7e+03      18      42 ..     328     352 ..     319     400 .. 0.75

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.005
      DUF835 19 gvkvlaitRenpkkirekvkienvkviwltkveeentvsPtnlekltetivkflkeaekgvvliDgle 86
                 v +++i   +p++++  ++i+ v+v+ + +  +e   +Pt  ++++++ v + ++ ++  v+ + +e
  EEA19775.1 14 IVALVMIAKMKPQDVAILLNIPRVSVYQIVQRAKEHGYDPTVNPRIEHEHVANNTRSGRPKVVTEAIE 81
                46789999999*****999***************************8766555555555667767766 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0029
      DUF835  16 vkegvkvlaitRenpkkirekvkienvkviwltkveeentvsPtnlekltetivkflkeaekgvvliDgle 86 
                   + v +++i   +p++++  ++i+ v+v+ + +  +e   +Pt  ++++++ v + ++ ++  v+ + +e
  EEA19775.1 110 RAQIVALVMIAKMKPQDVAILLNIPRVSVYQIVQRAKEHGYDPTVNPRIEHEHVANNTRSGRPKVVTEAIE 180
                 4455788999999******999***************************8766555555555667767766 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 1.7
      DUF835  36 kvkienvkviwltkveeentvsPtnlekltetivk 70 
                 + +i++++v+ l k ++ n+ +Pt  + lt+++++
  EEA19775.1 204 EAGISESSVLRLLKLNSFNKCKPTVKPGLTDKMKQ 238
                 55788889999999999999999999999998775 PP

  == domain 4  score: -2.4 bits;  conditional E-value: 4.4
      DUF835  18 egvkvlaitRenpkkirekvkienv 42 
                  ++++ +i R++++  re+ +++n+
  EEA19775.1 328 AEKELQIINRDREQAAREEWELNNT 352
                 4467778888888887777777665 PP

>> Fe_dep_repress  Iron dependent repressor, N-terminal DNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.0     0.019        17      22      51 ..      22      51 ..      20      56 .. 0.93
   2 ?    5.7   0.0     0.019        17      22      51 ..     121     150 ..     119     155 .. 0.93

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.019
                    SB-HHHHHHHHTS-HHHHHHHHHHHHHTTS CS
  Fe_dep_repress 22 vvktkdlaerLnvspssVsemlkkLekdGy 51
                    + k++d+a  Ln+   sV + +++ ++ Gy
      EEA19775.1 22 KMKPQDVAILLNIPRVSVYQIVQRAKEHGY 51
                    57899************************9 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.019
                     SB-HHHHHHHHTS-HHHHHHHHHHHHHTTS CS
  Fe_dep_repress  22 vvktkdlaerLnvspssVsemlkkLekdGy 51 
                     + k++d+a  Ln+   sV + +++ ++ Gy
      EEA19775.1 121 KMKPQDVAILLNIPRVSVYQIVQRAKEHGY 150
                     57899************************9 PP

>> HTH_IclR  IclR helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0       0.2   1.7e+02      19      47 ..      23      51 ..      11      51 .. 0.91
   2 ?    2.2   0.0      0.18   1.6e+02      19      47 ..     122     150 ..     106     150 .. 0.90
   3 ?    4.8   0.0     0.028        24      21      40 ..     198     217 ..     190     218 .. 0.81

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.2
                -BHHHHHHHHTS-HHHHHHHHHHHHHTTS CS
    HTH_IclR 19 ltlselArrtglpkStvhRlLqtLvelGy 47
                ++ +++A  + +p+ +v+ ++q   e+Gy
  EEA19775.1 23 MKPQDVAILLNIPRVSVYQIVQRAKEHGY 51
                88899****************99888887 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.18
                 -BHHHHHHHHTS-HHHHHHHHHHHHHTTS CS
    HTH_IclR  19 ltlselArrtglpkStvhRlLqtLvelGy 47 
                 ++ +++A  + +p+ +v+ ++q   e+Gy
  EEA19775.1 122 MKPQDVAILLNIPRVSVYQIVQRAKEHGY 150
                 88899****************99888887 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.028
                 HHHHHHHHTS-HHHHHHHHH CS
    HTH_IclR  21 lselArrtglpkStvhRlLq 40 
                    lA ++g++ S+v RlL+
  EEA19775.1 198 AEYLAYEAGISESSVLRLLK 217
                 556999************95 PP

>> HTH_Crp_2  Crp-like helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.0     0.049        42      21      50 ..      22      51 ..       6      61 .. 0.88
   2 ?    4.8   0.0     0.032        27      21      50 ..     121     150 ..      97     160 .. 0.81
   3 ?   -1.5   0.0       2.9   2.5e+03      25      43 ..     199     217 ..     196     218 .. 0.87

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.049
                EHHHHHHHHHTTSSHHHHHHHHHHHHHTTS CS
   HTH_Crp_2 21 pltqeelAsmlGltretvsrilseLkregl 50
                ++  ++ A +l++ r++v +i ++ k++g+
  EEA19775.1 22 KMKPQDVAILLNIPRVSVYQIVQRAKEHGY 51
                67789*******************999995 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.032
                 EHHHHHHHHHTTSSHHHHHHHHHHHHHTTS CS
   HTH_Crp_2  21 pltqeelAsmlGltretvsrilseLkregl 50 
                 ++  ++ A +l++ r++v +i ++ k++g+
  EEA19775.1 121 KMKPQDVAILLNIPRVSVYQIVQRAKEHGY 150
                 78889*******************999995 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 2.9
                 HHHHHHTTSSHHHHHHHHH CS
   HTH_Crp_2  25 eelAsmlGltretvsrils 43 
                 e lA   G++ ++v r+l+
  EEA19775.1 199 EYLAYEAGISESSVLRLLK 217
                 6799999*********997 PP

>> DUF1681  Protein of unknown function (DUF1681)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.0     0.019        16       4      52 ..      30      84 ..      28     117 .. 0.75
   2 ?    5.0   0.0     0.022        19       4      52 ..     129     183 ..     127     220 .. 0.79

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.019
     DUF1681  4 vllvakevhvYkippltsskgyraadwtl......ekeiftgrlrvlekgekvdi 52
                +ll +++v vY+i  +++++gy             ++++ +gr +v++++ +++i
  EEA19775.1 30 ILLNIPRVSVYQIVQRAKEHGYDPTVNPRiehehvANNTRSGRPKVVTEAIEASI 84
                78999*****************866554455555677788888888888766665 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.022
     DUF1681   4 vllvakevhvYkippltsskgyraadwtl......ekeiftgrlrvlekgekvdi 52 
                 +ll +++v vY+i  +++++gy             ++++ +gr +v++++ +++i
  EEA19775.1 129 ILLNIPRVSVYQIVQRAKEHGYDPTVNPRiehehvANNTRSGRPKVVTEAIEASI 183
                 78999*****************866544445555677777788888877766655 PP

>> Sigma70_r4  Sigma-70, region 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.1     0.016        14      11      45 ..      13      47 ..       9      49 .. 0.86
   2 ?    5.3   0.1     0.016        14      11      45 ..     112     146 ..     108     148 .. 0.86
   3 ?   -1.0   0.1       1.5   1.3e+03      16      40 ..     191     215 ..     180     217 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.016
                HHHHHHHTTT--HHHHHHHHTS-HHHHHHHHHHHH CS
  Sigma70_r4 11 evlelrfgeglTleEIgerlgiSrerVrqiekrAl 45
                +++ l+   ++  ++++  l+i+r  V qi  rA 
  EEA19775.1 13 QIVALVMIAKMKPQDVAILLNIPRVSVYQIVQRAK 47
                788888888888899******************96 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.016
                 HHHHHHHTTT--HHHHHHHHTS-HHHHHHHHHHHH CS
  Sigma70_r4  11 evlelrfgeglTleEIgerlgiSrerVrqiekrAl 45 
                 +++ l+   ++  ++++  l+i+r  V qi  rA 
  EEA19775.1 112 QIVALVMIAKMKPQDVAILLNIPRVSVYQIVQRAK 146
                 788888888888899******************96 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 1.5
                 HHTTT--HHHHHHHHTS-HHHHHHH CS
  Sigma70_r4  16 rfgeglTleEIgerlgiSrerVrqi 40 
                 r g++ + e ++ + giS++ V ++
  EEA19775.1 191 RAGREKSAEYLAYEAGISESSVLRL 215
                 558888999999999****998665 PP

>> MarR_2  MarR family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.0     0.051        43      22      50 ..      23      51 ..       9      51 .. 0.83
   2 ?    4.2   0.0     0.046        39      22      50 ..     122     150 ..     102     150 .. 0.83
   3 ?   -0.3   0.0       1.2     1e+03      17      43 ..     191     217 ..     179     218 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.051
                EEHHHHHHHHTSSHHHHHHHHHHHHHTTS CS
      MarR_2 22 ltvgelarrlglsksavsrilkrLvaaGL 50
                + ++++a  l++++ +v +i++r+ ++G+
  EEA19775.1 23 MKPQDVAILLNIPRVSVYQIVQRAKEHGY 51
                567899999******************98 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.046
                 EEHHHHHHHHTSSHHHHHHHHHHHHHTTS CS
      MarR_2  22 ltvgelarrlglsksavsrilkrLvaaGL 50 
                 + ++++a  l++++ +v +i++r+ ++G+
  EEA19775.1 122 MKPQDVAILLNIPRVSVYQIVQRAKEHGY 150
                 467899999******************98 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 1.2
                 TTTSEEEHHHHHHHHTSSHHHHHHHHH CS
      MarR_2  17 rpgrdltvgelarrlglsksavsrilk 43 
                 r gr+ ++  la + g+s s+v r+lk
  EEA19775.1 191 RAGREKSAEYLAYEAGISESSVLRLLK 217
                 5555448999999*********99997 PP

>> HTH_7  Helix-turn-helix domain of resolvase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.2     0.021        18      13      41 ..      13      42 ..       3      45 .. 0.76
   2 ?    4.9   0.1     0.033        29      21      41 ..     121     141 ..     108     144 .. 0.82
   3 ?   -1.0   0.0       2.3     2e+03      27      42 ..     201     216 ..     196     218 .. 0.77

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.021
                GGGSSTTTT.--STTTSSSS---SSSS--S CS
       HTH_7 13 rvvkLleeG.isiskIAkevnisRsTvYRy 41
                ++v+L+    ++ +++A+ +ni R +vY++
  EEA19775.1 13 QIVALVMIAkMKPQDVAILLNIPRVSVYQI 42
                56666553338889**************98 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.033
                 T--STTTSSSS---SSSS--S CS
       HTH_7  21 GisiskIAkevnisRsTvYRy 41 
                 +++ +++A+ +ni R +vY++
  EEA19775.1 121 KMKPQDVAILLNIPRVSVYQI 141
                 477799*************98 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 2.3
                 TSSSS---SSSS--SS CS
       HTH_7  27 IAkevnisRsTvYRyl 42 
                 +A e +is s+v R l
  EEA19775.1 201 LAYEAGISESSVLRLL 216
                 5778889999998865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (532 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       783  (0.0436723); expected 358.6 (0.02)
Passed bias filter:                      525  (0.0292822); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                        21  (0.00117129); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              21  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.43
# Mc/sec: 3714.73
//
Query:       EEA19776.1  [L=780]
Description: lipid A export ATP-binding/permease protein msbA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      1e-16   61.7   0.0    1.8e-16   60.9   0.0    1.4  1  ABC_tran      ABC transporter
    1.1e-06   28.5   3.9    6.4e-06   26.0   3.8    1.9  1  ABC_membrane  ABC transporter transmembrane region
  ------ inclusion threshold ------
       0.14   11.5   0.0       0.25   10.7   0.0    1.3  1  DnaB_C        DnaB-like helicase C terminal domain
       0.14   11.6   0.0       0.19   11.2   0.0    1.2  1  SMC_N         RecF/RecN/SMC N terminal domain


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.9   0.0   4.1e-20   1.8e-16       3     136 ..     440     574 ..     438     575 .. 0.87

  Alignments for each domain:
  == domain 1  score: 60.9 bits;  conditional E-value: 4.1e-20
                 EEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.......HHHTCHHHHHHHSTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxxx RF
    ABC_tran   3 nvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren.......esdeeiekalsklgl 94 
                 +v ++l++ge++   G  G GK+ L+++++g+ + t G+i            ++++kei++++qep l + +t+r+         + e+ +++++  gl
  EEA19776.1 440 DVCIDLNRGEIIICAGAVGRGKTILAMAILGEAHLTTGTI------------RVSSKEIAYCSQEPWLPS-VTIRDAisgggldLDLEWYNTVIDACGL 525
                 57789***********************************............7999*********77755.55****9999998556667777777777 PP

                 GG.......TTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 xx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  95 ke.......lkdtvvksspssLSgGqkqrvalarallkkpkllllDEpt 136
                 +         + t +++++ +LSgGqkqr+alara+ ++ ++l+lD+p+
  EEA19776.1 526 VPdfttfarGDMTLIEDNGINLSGGQKQRIALARAVYSRHRILVLDDPF 574
                 7767777776778888888*****************************7 PP

>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0   3.8   1.4e-09   6.4e-06      41     270 ..     156     372 ..     142     375 .. 0.88

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 1.4e-09
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHHHHSCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane  41 nvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsffdtnsvGellsrltndvsklrdglgeklglffqslltfvgglivmf 137
                    +++ +  +++l++++++  +++ +n +   ++ +l + + +  l++++  f +  + +l   +++d+++++++  +++ ++ + l +++g+++++ 
    EEA19776.1 156 QKFASTSSIVYLGMAVSGPTYQHQINRLRVMTRGALISLVHHQSLHMSTTGFKDSEAPTL---VSSDIDNIESFGETFHETWARLLEVIIGTMLLAA 249
                   6788888999****************************************9999999999...99******************************** PP

                   HHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane 138 ylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirtVkafgreeyflekfekaleeakkagikkaianglligitqll 234
                    +gw      +a+lpl+i+++     + + ++  e  ++ k+ + +  +l gi+ +k +g+e+++++ +   + e+  ++++   +   +++ +++l
    EEA19776.1 250 QIGW------FAFLPLVIVFA-----FRRHAEGLECGHTQKRLATVAAALGGIKSLKMMGMEDAVQSLISYLRSEEIGSSKRLRWILVTNNASANAL 335
                   ****......57888888776.....46788889999999************************************988888888888888888888 PP

                   HHHHHHHHH.HHHHHHHHTTSSTHHHHHHHHHHHHHH CS
  ABC_membrane 235 gllsyalal.wfGttlvisgelsvgdlvvflslfail 270
                   g ++ +l+l +++ tl   g l  +++++ ++l++++
    EEA19776.1 336 GIFAPVLTLiLYALTLENGGVLRADEVFTSVALLTMV 372
                   8887777774577777777999999988888887765 PP

>> DnaB_C  DnaB-like helicase C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   5.5e-05      0.25      12      55 ..     441     483 ..     432     493 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 5.5e-05
                 HCTSBXTTXEEEEEEXTTSSHHHHHHHHHHHHHHCSTSEEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      DnaB_C  12 ltsGlqkgdliiiAarpsmGktalalniaenaavkeklpvavfs 55 
                 +   l++g++ii A+  + Gkt la+ i  +a  ++  ++ v s
  EEA19776.1 441 VCIDLNRGEIIICAGAVGRGKTILAMAILGEAHLTTG-TIRVSS 483
                 556799**********************988775333.344444 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   4.1e-05      0.19     135     185 ..     304     591 ..      99     620 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 4.1e-05
                 T.................................................................................................. CS
                 x.................................................................................................. RF
       SMC_N 135 e.................................................................................................. 135
                 +                                                                                                  
  EEA19776.1 304 Qslisylrseeigsskrlrwilvtnnasanalgifapvltlilyaltlenggvlradevftsvalltmvthpanmvmtlipqaiaimanfdrvqsyvsq 402
                 044444444444444777777777777777777777777777777777777777777777777777777777777777777777777777777777777 PP

                 ................................................................................................... CS
                 ................................................................................................... RF
       SMC_N 136 ................................................................................................... 135
                                                                                                                    
  EEA19776.1 403 psiqdkreysaesnvrklasiqnvsitspstsltllldvcidlnrgeiiicagavgrgktilamailgeahlttgtirvsskeiaycsqepwlpsvtir 501
                 777777777777777777777777888888888888888888889999999999999999999999999999999999999999999999999999999 PP

                 ............................................CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHH CS
                 ............................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 136 ............................................lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellke 185
                                                             +LSgG+k+ +ala       ++++ + +lD+  +a+Dek v  + ++l +
  EEA19776.1 502 daisgggldldlewyntvidacglvpdfttfargdmtliedngiNLSGGQKQRIALA----RAVYSRHRILVLDDPFSAIDEKTVDCIIDRLLS 591
                 99999999999999999999999999999999999999999999*******987765....45789999***************9998877654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (780 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       565  (0.0315132); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.72u 0.29s 00:00:01.01 Elapsed: 00:00:00.48
# Mc/sec: 4892.52
//
Query:       EEA19777.1  [L=839]
Description: lipid A export ATP-binding/permease protein msbA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-16   61.5   0.0    2.1e-16   60.7   0.0    1.5  1  ABC_tran      ABC transporter
      9e-07   28.8   3.5    5.5e-06   26.2   3.4    2.0  1  ABC_membrane  ABC transporter transmembrane region
  ------ inclusion threshold ------
       0.15   11.3   0.0       0.27   10.5   0.0    1.3  1  DnaB_C        DnaB-like helicase C terminal domain
       0.16   11.4   0.0        0.2   11.1   0.0    1.2  1  SMC_N         RecF/RecN/SMC N terminal domain


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.7   0.0   4.6e-20   2.1e-16       3     136 ..     499     633 ..     497     634 .. 0.87

  Alignments for each domain:
  == domain 1  score: 60.7 bits;  conditional E-value: 4.6e-20
                 EEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.......HHHTCHHHHHHHSTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxxx RF
    ABC_tran   3 nvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren.......esdeeiekalsklgl 94 
                 +v ++l++ge++   G  G GK+ L+++++g+ + t G+i            ++++kei++++qep l + +t+r+         + e+ +++++  gl
  EEA19777.1 499 DVCIDLNRGEIIICAGAVGRGKTILAMAILGEAHLTTGTI------------RVSSKEIAYCSQEPWLPS-VTIRDAisgggldLDLEWYNTVIDACGL 584
                 57789***********************************............7999*********77755.55****9999998556667777777777 PP

                 GG.......TTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 xx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  95 ke.......lkdtvvksspssLSgGqkqrvalarallkkpkllllDEpt 136
                 +         + t +++++ +LSgGqkqr+alara+ ++ ++l+lD+p+
  EEA19777.1 585 VPdfttfarGDMTLIEDNGINLSGGQKQRIALARAVYSRHRILVLDDPF 633
                 7767777776778888888*****************************7 PP

>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.2   3.4   1.2e-09   5.5e-06      41     270 ..     215     431 ..     201     434 .. 0.88

  Alignments for each domain:
  == domain 1  score: 26.2 bits;  conditional E-value: 1.2e-09
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHHHHSCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane  41 nvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsffdtnsvGellsrltndvsklrdglgeklglffqslltfvgglivmf 137
                    +++ +  +++l++++++  +++ +n +   ++ +l + + +  l++++  f +  + +l   +++d+++++++  +++ ++ + l +++g+++++ 
    EEA19777.1 215 QKFASTSSIVYLGMAVSGPTYQHQINRLRVMTRGALISLVHHQSLHMSTTGFKDSEAPTL---VSSDIDNIESFGETFHETWARLLEVIIGTMLLAA 308
                   6788888999****************************************9999999999...99******************************** PP

                   HHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane 138 ylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirtVkafgreeyflekfekaleeakkagikkaianglligitqll 234
                    +gw      +a+lpl+i+++     + + ++  e  ++ k+ + +  +l gi+ +k +g+e+++++ +   + e+  ++++   +   +++ +++l
    EEA19777.1 309 QIGW------FAFLPLVIVFA-----FRRHAEGLECGHTQKRLATVAAALGGIKSLKMMGMEDAVQSLISYLRSEEIGSSKRLRWILVTNNASANAL 394
                   ****......57888888776.....46788889999999************************************988888888888888888888 PP

                   HHHHHHHHH.HHHHHHHHTTSSTHHHHHHHHHHHHHH CS
  ABC_membrane 235 gllsyalal.wfGttlvisgelsvgdlvvflslfail 270
                   g ++ +l+l +++ tl   g l  +++++ ++l++++
    EEA19777.1 395 GIFAPVLTLiLYALTLENGGVLRADEVFTSVALLTMV 431
                   8887777774577777777999999988888887765 PP

>> DnaB_C  DnaB-like helicase C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0     6e-05      0.27      12      55 ..     500     542 ..     491     552 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 6e-05
                 HCTSBXTTXEEEEEEXTTSSHHHHHHHHHHHHHHCSTSEEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      DnaB_C  12 ltsGlqkgdliiiAarpsmGktalalniaenaavkeklpvavfs 55 
                 +   l++g++ii A+  + Gkt la+ i  +a  ++  ++ v s
  EEA19777.1 500 VCIDLNRGEIIICAGAVGRGKTILAMAILGEAHLTTG-TIRVSS 542
                 556799**********************988775333.344444 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   4.4e-05       0.2     135     185 ..     361     650 ..     106     679 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 4.4e-05
                 T.................................................................................................. CS
                 x.................................................................................................. RF
       SMC_N 135 e.................................................................................................. 135
                                                                                                                    
  EEA19777.1 361 Avqslisylrseeigsskrlrwilvtnnasanalgifapvltlilyaltlenggvlradevftsvalltmvthpanmvmtlipqaiaimanfdrvqsyv 459
                 044444444444444447777777777777777777777777777777777777777777777777777777777777777777777777777777777 PP

                 ................................................................................................... CS
                 ................................................................................................... RF
       SMC_N 136 ................................................................................................... 135
                                                                                                                    
  EEA19777.1 460 sqpsiqdkreysaesnvrklasiqnvsitspstsltllldvcidlnrgeiiicagavgrgktilamailgeahlttgtirvsskeiaycsqepwlpsvt 558
                 777777777777777777777778888888888888888888888899999999999999999999999999999999999999999999999999999 PP

                 ..............................................CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHH CS
                 ..............................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 136 ..............................................lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellke 185
                                                               +LSgG+k+ +ala       ++++ + +lD+  +a+Dek v  + ++l +
  EEA19777.1 559 irdaisgggldldlewyntvidacglvpdfttfargdmtliedngiNLSGGQKQRIALA----RAVYSRHRILVLDDPFSAIDEKTVDCIIDRLLS 650
                 9999999999999999999999999999999999999999999999*******987765....45789999***************9998877654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (839 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       668  (0.0372581); expected 358.6 (0.02)
Passed bias filter:                      449  (0.0250432); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.74u 0.31s 00:00:01.05 Elapsed: 00:00:00.48
# Mc/sec: 5260.37
//
Query:       EEA19778.1  [L=190]
Description: DUF652 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.6e-38  130.4   1.0    6.8e-38  129.1   0.4    1.8  2  Fcf1      Fcf1
    1.4e-12   47.9   0.4    4.8e-12   46.2   0.1    1.8  2  PIN_9     PIN like domain


Domain annotation for each model (and alignments):
>> Fcf1  Fcf1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0      0.17   1.5e+03      26      52 ..       7      38 ..       2      82 .. 0.68
   2 !  129.1   0.4   7.6e-42   6.8e-38       1      99 []      87     183 ..      87     183 .. 0.98

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.17
                -HHHHHHHTTSEEE----.....SS---HHHH CS
        Fcf1 26 lkealkiaktferlkCnh.....kkptsaddC 52
                +++  ++ + +  + C       +k +++dd 
  EEA19778.1  7 VRKFAQVKRAITLRDCRLnpqepEKDKKKDDN 38
                44555555567777776644444444444444 PP

  == domain 2  score: 129.1 bits;  conditional E-value: 7.6e-42
                 HHCTS-EEEEEEHHHHHHHHHCT..-HHHHHHHT.T.SEEE----SS---HHHHHHHHH-BTB-TT-EEEE-S-HHHHHHHHTSTT--EEEEE--EEEE CS
        Fcf1   1 ktLqakvkpliTqCviaeleklgkklkealkiak.t.ferlkCnhkkptsaddClvsvvkkkknkkryivAtqDkdlrrrlrkipgvPilyikrsvmvl 97 
                 ++L+ak++p+iT+Cv+aeleklg+k++ al+iak + fer kC+h ++t+addClv++v  k  ++ yivAt+Dkdl+rr+rkipgvPi+ ++r ++v+
  EEA19778.1  87 DCLYAKCTPVITDCVLAELEKLGQKYRLALRIAKdPrFERIKCDH-RGTYADDCLVDRVI-K--HRVYIVATNDKDLKRRIRKIPGVPIMNVARGKYVI 181
                 79********************************978********.9*************.4..9********************************** PP

                 -- CS
        Fcf1  98 Ek 99 
                 E+
  EEA19778.1 182 ER 183
                 96 PP

>> PIN_9  PIN like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0      0.15   1.3e+03      49      82 ..       4      41 ..       2      50 .. 0.64
   2 !   46.2   0.1   5.3e-16   4.8e-12       1     111 [.      64     172 ..      64     178 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.15
       PIN_9 49 kgkertaakvalsLaer.ceiveae...eekaDdaile 82
                k+k r+ a+v ++++ r c++  +e   ++k Dd +++
  EEA19778.1  4 KKKVRKFAQVKRAITLRdCRLNPQEpekDKKKDDNVVR 41
                55667777777777555577766665555567776665 PP

  == domain 2  score: 46.2 bits;  conditional E-value: 5.3e-16
       PIN_9   1 vilDtnaLmipvqfgvdifeelerll.gsvelvvpkavleELerlakagkgkertaakvalsL.aerceiveaeeekaDdailelakeldaavlvTnDr 97 
                 v++Dtn+L   vq +++++  +   l  +   v+ + vl+ELe+l     +k r a ++a++   er+++ ++++ +aDd +++   + ++ +++TnD+
  EEA19778.1  64 VLVDTNFLSHSVQHKLEVIPTMMDCLyAKCTPVITDCVLAELEKL----GQKYRLALRIAKDPrFERIKC-DHRGTYADDCLVDRVIKHRVYIVATNDK 157
                 799****************9999888899****************....778999******985566665.555699********************** PP

       PIN_9  98 eLkkrlle.kgipvi 111
                 +Lk+r+++  g+p++
  EEA19778.1 158 DLKRRIRKiPGVPIM 172
                 ******983467766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (190 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       491  (0.0273858); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1264.26
//
Query:       EEA19779.1  [L=604]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.5e-92  308.9   0.0    3.4e-92  308.4   0.0    1.2  1  XPG_I_2   XPG domain containing
    0.00021   21.6   0.0     0.0005   20.4   0.0    1.6  1  XPG_I     XPG I-region


Domain annotation for each model (and alignments):
>> XPG_I_2  XPG domain containing
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  308.4   0.0   3.8e-96   3.4e-92       2     249 .]     158     437 ..     157     437 .. 0.99

  Alignments for each domain:
  == domain 1  score: 308.4 bits;  conditional E-value: 3.8e-96
     XPG_I_2   2 ppfmvpavieaLknrw.........................kakditevvpgEADkfcAvlA.rklgcaVLTsDSDLlvhdlgeegsvifldsielssr 74 
                 +pfmv+av+e+Lk+rw                         +++dite+++gEAD+fcA+lA ++ g+a+LTsDSDLl++d+g+e+++if+d+i+++++
  EEA19779.1 158 NPFMVSAVVEDLKSRWthsemslylprnlidiykannnqyhPWSDITEIITGEADVFCAALAsQNPGAAILTSDSDLLLFDIGPESTIIFFDTIRVEDA 256
                 89************************************************************************************************8 PP

     XPG_I_2  75 vkkaepk.sklsiratkyrpaeiakklgvpslqllAfelnrdphlklaelvkrakssskvaeksseyvaflkeye.essevksatsanalqlldprvse 171
                 ++k  p+  +++i+a+ky+p +ia++lg+p+l++lA+eln++p++klaelv+rak++s+++ k+s+yv+fl+ey+ ++  +++ ++a+alq+ld+r+se
  EEA19779.1 257 GNKIVPTeLPMTIKAMKYHPPSIADRLGIPALSYLAHELNQSPRSKLAELVRRAKIASDLTPKTSAYVSFLEEYDlQNFLQYDPSEAHALQNLDTRISE 355
                 899999989******************************************************************99********************** PP

     XPG_I_2 172 Lllqleqa.aafnkeeeapevYlpflvedhsrrcaWeegkdiRllAysllnls...skgerketvlEylrkgqriakeevel 249
                 L++q++++ ++f+++++a+++Ylpflvedhsr+caW+e+ ++R+lAysllnl+   ++g+r ++v+E++r+g+r++ ++++l
  EEA19779.1 356 LFVQCLWTnNNFQDQRQALHIYLPFLVEDHSRKCAWAESVEFRRLAYSLLNLNgalTTGSRLTAVIECVRRGRRLCLDNIDL 437
                 ********************************************************99*******************99987 PP

>> XPG_I  XPG I-region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.0   5.5e-08    0.0005      12      41 ..     209     238 ..     206     276 .. 0.87

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 5.5e-08
                 S-HHHHHHHHHHTTSSSEEE-SSSHHHHTT CS
       XPG_I  12 gEAEAqcayLqkkglvdaviseDsDlllFG 41 
                 gEA+  ca+L++++   a+++ DsDlllF 
  EEA19779.1 209 GEADVFCAALASQNPGAAILTSDSDLLLFD 238
                 8****************************5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (604 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       402  (0.0224218); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.27s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 3836.66
//
Query:       EEA19780.1  [L=1022]
Description: snoRNA binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    8.8e-73  244.6   0.0    1.4e-72  244.0   0.0    1.2  1  Utp21        Utp21 specific WD40 associated putative domain
    2.8e-16   59.6  28.4    0.00023   21.9   0.4   10.6 10  WD40         WD domain, G-beta repeat
    3.2e-14   53.0   0.1      0.028   14.7   0.0    6.2  6  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
     0.0098   14.9   0.3        0.2   10.5   0.0    3.0  3  PALB2_WD40   Partner and localizer of BRCA2 WD40 domain
  ------ inclusion threshold ------
      0.049   13.1   0.0       0.29   10.5   0.0    2.2  2  DUF5046      Domain of unknown function (DUF5046)
      0.089   12.7   0.0       0.38   10.6   0.0    2.1  2  eIF2A        Eukaryotic translation initiation factor eIF2A
        0.1   12.5   0.0       0.21   11.5   0.0    1.4  1  Bys1         Blastomyces yeast-phase-specific protein


Domain annotation for each model (and alignments):
>> Utp21  Utp21 specific WD40 associated putative domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  244.0   0.0   5.4e-76   1.4e-72      10     233 .]     789    1019 ..     782    1019 .. 0.89

  Alignments for each domain:
  == domain 1  score: 244.0 bits;  conditional E-value: 5.4e-76
                  ..XX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXX-HHHHHHHHTT------. CS
       Utp21   10 eeedadvkspsseqlsedLiTLSlvpksrwqtLlnLDlIKeRnkPkeapkkpekaPFFLptlaglegkfasekedeeseedeeeeeeeesrilkldk 106 
                  ++ed+d ++ s eql++d++TLS+vp++ wqtL+nLD++++RnkPke+ k+pekaPFFLp+l++++               ++++e+e+  i+k+  
  EEA19780.1  789 DDEDQDKTAISFEQLDRDMTTLSIVPRATWQTLINLDIVRARNKPKEPAKAPEKAPFFLPSLQDDQSAAPIA-------GIDDQKESERMPISKSIL 878 
                  344545555555***************************************************988876655.......445555555566666654 PP

                  ------HHHHHHHHHHSS--HHHHHHHHH-S-HHHHHT----...----S-SHHHHHHHHHHHHHTTTS-HHHHHHHHHHHHHHTTTTTTT-SH... CS
       Utp21  107 lgteseftklLeegsetgdysefleyLkslspsaidleirsL...esaesleelvafvkaltarLksrrdfeLvqailsvfLkvHgdviaeeeee.. 198 
                  ++++s  +klL++gs+++++s+f++y+kslsp +idleirsL     ++ + elv+fv+alt+rL  ++dfeLv+a+++vfLkvH d+i  + e   
  EEA19780.1  879 SQQDSPVSKLLRSGSNNKNFSPFIDYFKSLSPGKIDLEIRSLnvqLLRDGYCELVSFVDALTERLCLKKDFELVNAWMAVFLKVHSDLICGDGELat 975 
                  5689**************************************7766789******************************************998799 PP

                  ..........HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT CS
       Utp21  199 .........elkealeelkeeqeeewerldelvkyclgvvgflr 233 
                           +l++al  +k+eqe+e++rl+el++yc+g+vgflr
  EEA19780.1  976 vssdedlvsTLRTALMGWKKEQESEAKRLSELMGYCRGIVGFLR 1019
                  ******************************************98 PP

>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.2      0.24   6.3e+02      21      38 .]     149     165 ..     136     165 .. 0.81
   2 !    9.1   0.0   0.00099       2.5       6      38 .]     188     216 ..     184     216 .. 0.69
   3 ?    0.5   0.0      0.53   1.4e+03       8      38 .]     277     317 ..     269     317 .. 0.61
   4 ?    3.9   0.0     0.044   1.1e+02       8      37 ..     335     367 ..     322     367 .. 0.75
   5 !    9.1   0.1     0.001       2.6       2      33 ..     379     419 ..     378     421 .. 0.90
   6 ?    0.9   0.1      0.37   9.6e+02      12      34 ..     535     557 ..     526     561 .. 0.78
   7 !   17.6   0.1     2e-06    0.0052       8      38 .]     587     618 ..     579     618 .. 0.91
   8 ?    1.8   0.0       0.2   5.1e+02      12      36 ..     630     659 ..     620     661 .. 0.71
   9 !   21.9   0.4   9.1e-08   0.00023       7      38 .]     674     703 ..     666     703 .. 0.85
  10 ?    3.6   0.1     0.053   1.4e+02       9      29 ..     707     735 ..     705     745 .. 0.73

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.24
                 TSSEEEEEETTSEEEEEE CS
        WD40  21 dgawlasGsdDgtvriWd 38 
                  g+w++ ++  +++ +W+
  EEA19780.1 149 FGSWIIGCC-ERSIQVWK 165
                 589*99556.*******6 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.00099
                 EEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   6 tltGHssvtslafspdgawlasGsdDgtvriWd 38 
                 ++tGH  v+ +  + + + ++ G +Dgtv +W+
  EEA19780.1 188 VFTGH--VCNM--PTYLNKIFVGRYDGTVELWN 216
                 799**..5555..222244556*88*******8 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.53
                 ESSSSEEEEEEETTSSE..........EEEEE.TTSEEEEEE CS
        WD40   8 tGHssvtslafspdgaw..........lasGs.dDgtvriWd 38 
                 + H ++ts++f  dg            +a++s + g v +Wd
  EEA19780.1 277 KSH-PITSISFRTDGMGagedgrmagvMATASmYSGDVTLWD 317
                 467.89999866666545555555554444442477777776 PP

  == domain 4  score: 3.9 bits;  conditional E-value: 0.044
                 ESSSS....EEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   8 tGHss....vtslafspdgawlasGsdDgtvriW 37 
                 t++ s    v+ + f + ++ ++s+++D+ ++ W
  EEA19780.1 335 TAQ-SsdsgVNKIEFLDGQPVIVSSGRDNALKTW 367
                 344.1346799999*********9999**99988 PP

  == domain 5  score: 9.1 bits;  conditional E-value: 0.001
                 EEEEEEESS.SSEEEEE........EETTSSEEEEEETTSE CS
        WD40   2 qclrtltGH.ssvtsla........fspdgawlasGsdDgt 33 
                 ++l++  GH   v+sl+         ++ g+wl+s+s+D++
  EEA19780.1 379 RPLHSRGGHaAAVCSLRflpsasdgSDSIGKWLLSASRDRS 419
                 5899999**777*****999999999999999*****9*97 PP

  == domain 6  score: 0.9 bits;  conditional E-value: 0.37
                 SEEEEEEETTSSEEEEEETTSEE CS
        WD40  12 svtslafspdgawlasGsdDgtv 34 
                  v s+a s  g++ a Gs  g +
  EEA19780.1 535 EVKSVAISNCGTFAAVGSAGGII 557
                 499**********9999976665 PP

  == domain 7  score: 17.6 bits;  conditional E-value: 2e-06
                 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +GH + +t+la +  ++ ++s++ Dg++++Wd
  EEA19780.1 587 SGHtKAITGLAIDNLNRNVVSCGLDGKLKFWD 618
                 6**999*************************9 PP

  == domain 8  score: 1.8 bits;  conditional E-value: 0.2
                 S.....EEEEEEETTSSEEE.EEETTSEEEE CS
        WD40  12 s.....vtslafspdgawla.sGsdDgtvri 36 
                 +     +t+l+fs+ + + a s++ D ++r+
  EEA19780.1 630 WapmtaITGLRFSSINELAAlSCD-DLSIRV 659
                 155555999999999999654777.*99998 PP

  == domain 9  score: 21.9 bits;  conditional E-value: 9.1e-08
                 EESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   7 ltGHssvtslafspdgawlasGsdDgtvriWd 38 
                 ++G+  ++++ fs dg+w++++s+D  +r+Wd
  EEA19780.1 674 CRGQ--INDFVFSIDGRWIIAASMDSIIRVWD 703
                 5677..99999999******99*********9 PP

  == domain 10  score: 3.6 bits;  conditional E-value: 0.053
                 SS.SS.......EEEEEEETTSSEEEEEE CS
        WD40   9 GH.ss.......vtslafspdgawlasGs 29 
                 GH  +        t+lafs  g +la+++
  EEA19780.1 707 GHlVDifrvpttCTALAFSGTGEYLATAH 735
                 66644444434458999*********986 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.0   2.6e-05     0.066      32      89 ..     217     286 ..     201     289 .. 0.77
   2 !   11.6   0.0    0.0001      0.26      34      82 ..     529     577 ..     504     586 .. 0.88
   3 ?    4.2   0.0     0.021        55      33      89 ..     585     641 ..     577     643 .. 0.87
   4 !    8.0   0.0    0.0014       3.6      39      76 ..     634     671 ..     629     677 .. 0.92
   5 !   14.7   0.0   1.1e-05     0.028       2      81 ..     640     718 ..     639     727 .. 0.89
   6 ?   -1.1   0.0      0.97   2.5e+03      41      59 ..     719     737 ..     715     754 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.6e-05
  ANAPC4_WD40  32 l..........eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksek..avtclgW 89 
                  +          +++++d  v++++  p  +l+a+ay  g+v l ++ s +v+ sl+++++k   +t++++
   EEA19780.1 217 VssgkllyrfsPATAKDDAVTAIEATPVLSLIAIAYRSGTVVLRNVDSDEVLMSLNASTSKshPITSISF 286
                  3333444444788999*************************************99988776556777766 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 0.0001
  ANAPC4_WD40  34 edkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksek 82 
                  e++++ ev+s+a ++ g++ av+ + g + +++ +sg+  + ++ +s+k
   EEA19780.1 529 ETSDGTEVKSVAISNCGTFAAVGSAGGIIDVYNLQSGQRRQRFPPSSSK 577
                  67899**********************************9999988775 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.021
  ANAPC4_WD40  33 eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                  +++++ + +++La  + ++  +    dg++++ d +sg+++  l+ +  +a+t l +
   EEA19780.1 585 SASGHTKAITGLAIDNLNRNVVSCGLDGKLKFWDFNSGHLLADLDWAPMTAITGLRF 641
                  66788999************99999******************99999988888876 PP

  == domain 4  score: 8.0 bits;  conditional E-value: 0.0014
  ANAPC4_WD40  39 sevrsLaWkpdgklLavaysdgevrlldaesgkvvhsl 76 
                    +++L+++  ++l a +++d ++r++d e++kvv++l
   EEA19780.1 634 TAITGLRFSSINELAALSCDDLSIRVVDLETKKVVREL 671
                  5799******************************9875 PP

  == domain 5  score: 14.7 bits;  conditional E-value: 1.1e-05
  ANAPC4_WD40   2 swcptmDLiAlatedgellvfRlngqrvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvkse 81 
                  ++++ ++L Al  +d +++v  l+ ++v+     +  ++++++ ++ dg+ +  a  d+ +r+ d  +g++v  ++v ++
   EEA19780.1 640 RFSSINELAALSCDDLSIRVVDLETKKVVRE-LWGCRGQINDFVFSIDGRWIIAASMDSIIRVWDLPTGHLVDIFRVPTT 718
                  6788899********************9987.578899*********************************998887665 PP

  == domain 6  score: -1.1 bits;  conditional E-value: 0.97
  ANAPC4_WD40  41 vrsLaWkpdgklLavaysd 59 
                   ++La++  g+ La a++ 
   EEA19780.1 719 CTALAFSGTGEYLATAHAG 737
                  5899**********99873 PP

>> PALB2_WD40  Partner and localizer of BRCA2 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0      0.29   7.5e+02      54      73 ..     153     172 ..     150     177 .. 0.83
   2 !   10.5   0.0   7.9e-05       0.2     201     313 ..     211     322 ..     202     338 .. 0.78
   3 ?   -0.5   0.0      0.18   4.6e+02     193     223 ..     690     720 ..     684     730 .. 0.78

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.29
  PALB2_WD40  54 ivtacesavslWksldakqW 73 
                 i++ ce ++ +Wk  + +++
  EEA19780.1 153 IIGCCERSIQVWKNPSFEHY 172
                 99***********8776665 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 7.9e-05
  PALB2_WD40 201 niviWnlktGqllkkieigesyqasvclkaysdsG.llfvvlshphakesesakkpvfkliainPktarsvevllytlPeGqtGryleGdvkdqlaaav 298
                  + +Wn+ +G+ll +++   + +++v       +  l ++ ++   +  +    ++   l+ +n  t++s  + + ++ +   G   +G + + +a+a 
  EEA19780.1 211 TVELWNVSSGKLLYRFSPATAKDDAVTA--IEATPvLSLIAIAYRSGTVVLRNVDSDEVLMSLNASTSKSHPITSISFRTDGMGAGEDGRMAGVMATAS 307
                 5779999999999999998888887753..33333033445566666666666677777999*****************9999**************** PP

  PALB2_WD40 299 ltsGaiavWdlllgh 313
                 + sG +++Wdl  g 
  EEA19780.1 308 MYSGDVTLWDLNNGG 322
                 ***********9863 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 0.18
  PALB2_WD40 193 llgttvlnniviWnlktGqllkkieigesyq 223
                 ++++++++ i +W+l tG l++ +++  +++
  EEA19780.1 690 IIAASMDSIIRVWDLPTGHLVDIFRVPTTCT 720
                 5667777778899999999998888877665 PP

>> DUF5046  Domain of unknown function (DUF5046)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0      0.65   1.7e+03     146     170 ..     252     276 ..     201     329 .. 0.58
   2 ?   10.5   0.0   0.00011      0.29      77     136 ..     586     647 ..     577     685 .. 0.80

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.65
     DUF5046 146 edyetiairlygaqGlvsdlaisaa 170
                  +  t+ +r  +++ ++  l +s++
  EEA19780.1 252 YRSGTVVLRNVDSDEVLMSLNASTS 276
                 2223333333333333333333333 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00011
     DUF5046  77 etGektpvy..dvdardktvavyatdgilrvydkttGalltdvevepveeqqsvrvsavgeG 136
                 ++G  +++    +d  +++v    +dg l+ +d ++G ll+d + +p+     +r s++ e 
  EEA19780.1 586 ASGHTKAITglAIDNLNRNVVSCGLDGKLKFWDFNSGHLLADLDWAPMTAITGLRFSSINEL 647
                 6899999997789999****************************999988888887777665 PP

>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.0         4     1e+04     123     136 ..     610     623 ..     604     632 .. 0.74
   2 ?   10.6   0.0   0.00015      0.38     101     163 ..     676     736 ..     658     750 .. 0.87

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 4
                 SS-EEEEEETTTTE CS
       eIF2A 123 laGeleiwdvkkkk 136
                 l G+l++wd ++ +
  EEA19780.1 610 LDGKLKFWDFNSGH 623
                 78999999977654 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00015
                 ES--EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE-T.T--EEEE-TTSSEEEEEE- CS
       eIF2A 101 qkrNtiffspkgklvllaGfgnlaGeleiwdvkkkkkiakaeaa.natlvewspdgryvlTatt 163
                  + N  +fs  g+ ++ a + ++   + +wd  + + +  ++ + ++t + +s +g+y++Ta  
  EEA19780.1 676 GQINDFVFSIDGRWIIAASMDSI---IRVWDLPTGHLVDIFRVPtTCTALAFSGTGEYLATAHA 736
                 5789******************9...********999999998626799************976 PP

>> Bys1  Blastomyces yeast-phase-specific protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   8.3e-05      0.21      96     134 ..     325     363 ..     309     377 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 8.3e-05
        Bys1  96 ggnpfeghkltlkssddrcpriewpegiptgvssgscgs 134
                  g   + h +t +ssd ++ +ie+ +g p  vssg   +
  EEA19780.1 325 TGVLRSAHDMTAQSSDSGVNKIEFLDGQPVIVSSGRDNA 363
                 4555678***************************97655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1022 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       454  (0.0253221); expected 358.6 (0.02)
Passed bias filter:                      403  (0.0224776); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.73u 0.29s 00:00:01.02 Elapsed: 00:00:00.44
# Mc/sec: 6976.92
//
Query:       EEA19781.1  [L=1345]
Description: actin cytoskeleton organization and biogenesis protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
   1.1e-112  377.1   0.0   1.5e-112  376.7   0.0    1.2  1  His_Phos_2  Histidine phosphatase superfamily (branch 2)
    1.5e-37  127.6   0.0    3.3e-37  126.5   0.0    1.6  1  PPIP5K2_N   Diphosphoinositol pentakisphosphate kinase 2 N-te
    9.7e-06   25.3   0.0    2.4e-05   24.0   0.0    1.5  1  RimK        RimK-like ATP-grasp domain


Domain annotation for each model (and alignments):
>> His_Phos_2  Histidine phosphatase superfamily (branch 2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  376.7   0.0  2.6e-116  1.5e-112       1     383 []     687    1281 ..     687    1281 .. 0.98

  Alignments for each domain:
  == domain 1  score: 376.7 bits;  conditional E-value: 2.6e-116
                  EEEEEEEEEE--SBB-SHHHHHHHHHHHHHHHH......................................HHCHHTGCCGGGGT............ CS
  His_Phos_2    1 eLksvvvviRHGdRtPkqkvkksvtspiflsllkkhke.............................Klkqlktalekkghfpgtyrkv........ 60  
                  +Lk++v+viRH+dRtPkqk+k ++ s+ f++ll +h+e                             Klk+lk +lekkg++pgt+ ++        
  EEA19781.1  687 KLKGMVAVIRHADRTPKQKFKFTFHSQPFVDLLRGHEEevvikgeaalasvaaavrvsmeqgledmdKLKLLKVSLEKKGNWPGTKVQIkpmfrkrr 783 
                  69*********************************************************************************************** PP

                  .....................................................................--SSSTTS.B-HHHHHHHHHHHHHHHHH CS
  His_Phos_2   61 ................................................................eveklqlilkwggelthaGrkqaeelGrqfrqr 93  
                                                                                    +klql++kwgge+tha+r+qa++lG  +r +
  EEA19781.1  784 peemsggieppsspqvknaplpedpatasqespsdseklarsqtrsdsisgptfsrfsaaendlILDKLQLVIKWGGEPTHAARYQAQDLGMTMRDD 880 
                  ***************************************************************999******************************* PP

                  CHTCCHTTSS--TTEEEEEESSHHHHHHHHHHHHHHCHCCC---S-TTSTTGGG-TTTTCCCEEEHHHHCCCCHHCTTSHHTCHHHC.......HHH CS
  His_Phos_2   94 YplgLlrlhltykdlkirassegRviaSAaafakGllglegeltdllskdkdllddsnaakdlldeakkklkelltegaeacpafew.......pik 183 
                   + ++++++l  +d+ i++sse Rv +SA+++a  +l++++  +d+++++kdllddsnaakd++d++kkklk ll+eg+ a+++f+w       p  
  EEA19781.1  881 LK-LMNKEAL--NDVRIFTSSEPRVSTSAQIWACSFLDEKELPEDFIQVRKDLLDDSNAAKDVMDKVKKKLKLLLREGS-APSQFTWpkdnfpePSV 973 
                  **.*****99..*************************9999999***********************************.***************** PP

                  TGGHCHHHHCHCCCCCHHHHHHHCHHH.........................CTTEEEE-HHHHHHHHHHHHHHHHHHCT-TTGGGCTH..HCHHHH CS
  His_Phos_2  184 vakrvdelvkylkedmdeniakrleql.........................cpgesnllakerwdklercfyeknkfdiskicdlydemkydalhn 255 
                  v  +v++l+ky++ +m++n+  rl                            c+ge+  l+kerw+kl+ +f++++k d+ski++lyd+mk dalhn
  EEA19781.1  974 VLATVVQLMKYHRVVMRHNFH-RLARSdivdvpgnppknpdspsvdsiqgrwCTGEDAELFKERWEKLFAEFCDTEKVDPSKISELYDSMKFDALHN 1069
                  *********************.665555778889999999999****************************************************** PP

                  HH......................................................................................HHHHHHHHH CS
  His_Phos_2  256 ry......................................................................................lkdleelyk 266 
                  r+                                                                                      l++l+elyk
  EEA19781.1 1070 RQflewvfippdgfkvkeqsglpsqqliesdkfeektdngtlaeiisfkkralsivesrrfgrledaydnyfklhgnpnskrkksderLVKLRELYK 1166
                  ************************************************************************************************* PP

                  C.............TTTCCCCHHHHHHHHHHHHHHHCTSSSEECCSCCCECS-SEEEEEE-HHHHHHHHHHC...TTTTTBTTB.SSS.TTT..HCC CS
  His_Phos_2  267 lakv.....ipqEygigpeeklkiGllllnpllkkilndlqrtreeatperhvrlrlyfthdshiysllnaL...glpeelagedslaaldrlsasp 355 
                  lakv     +pqEygi+++ekl+iGll+++pll++i +dl + +     + +++ ++yft++shiy+lln++   g+ +++++           a+p
  EEA19781.1 1167 LAKVlfdyiTPQEYGIKDSEKLEIGLLTSLPLLREIVRDLEEVQ----ASPDAKSFFYFTKESHIYTLLNCIlegGIQTKIKRR----------AIP 1249
                  ********************************************....99**********************************..........*** PP

                  CS-CT-EEEEEEEEE.TCTTT...EEEEEEEC CS
  His_Phos_2  356 elpymsqivfelyed.ssekk...fyvrllls 383 
                  el+y+sqi+felye+ +se++   +++r+++s
  EEA19781.1 1250 ELDYLSQICFELYEAkDSETDtfsYSIRISIS 1281
                  **************754444457799**9875 PP

>> PPIP5K2_N  Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  126.5   0.0   5.6e-41   3.3e-37       2      90 .]     224     312 ..     223     312 .. 0.99

  Alignments for each domain:
  == domain 1  score: 126.5 bits;  conditional E-value: 5.6e-41
   PPIP5K2_N   2 kvgvcamekkakskpmkeilerlekfeelevvifeeevileepveeWPlcdvlisfyskgfPlekaieYaklrkpflindleaqelllD 90 
                 ++gvca++ ka+skp ++il+rl++ ++l+v++f+++vil+e ve+WP+cd+li+f+s+gfPl+kai+Yaklrkpf++ndl +q++l+D
  EEA19781.1 224 RIGVCALDVKARSKPSQNILTRLQSKGDLDVIVFGDKVILDEAVENWPVCDFLIAFFSDGFPLDKAIAYAKLRKPFCVNDLPMQKILWD 312
                 69**************************************************************************************9 PP

>> RimK  RimK-like ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.0   0.0   3.9e-09   2.4e-05      76     165 ..     452     543 ..     442     559 .. 0.90

  Alignments for each domain:
  == domain 1  score: 24.0 bits;  conditional E-value: 3.9e-09
                 -EEEEE--SS-SEEEEEEEETTEEEEEEEEE-..-SSS----TTTT-EEEE----HHHHHHHHHHHHHCT-SEEEEEEEEETTEEEEEEEES CS
        RimK  76 ilvqeyieeaenediRvlvvddevvaalrrvs..keGdFRsnlhrGgvaeklqlseeekelAikaakamelvvaGvDllrakrgllvlEvns 165
                  l  +++   + ed++   v+ +   a  r+s   +G  R n h        +l++ee  +A k+++  +  ++G D+lr  +  +v++vn 
  EEA19781.1 452 YLYEQFLRVDNAEDVKAYTVGPDFCHAETRKSpvVDGVVRRNTHGKELRYITNLTKEEAAMAAKISNGFGQRICGFDMLRVGDRSYVIDVNG 543
                 58899********************99999874469********9999999****************************************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1345 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       701  (0.0390987); expected 358.6 (0.02)
Passed bias filter:                      512  (0.0285571); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.90u 0.32s 00:00:01.22 Elapsed: 00:00:00.51
# Mc/sec: 7890.08
//
Query:       EEA19782.1  [L=998]
Description: lipase/serine esterase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.8e-41  139.8   0.0    2.8e-39  134.9   0.0    2.7  1  DUF676    Putative serine esterase (DUF676)


Domain annotation for each model (and alignments):
>> DUF676  Putative serine esterase (DUF676)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  134.9   0.0   1.5e-43   2.8e-39       3     214 ..     273     550 ..     271     554 .. 0.88

  Alignments for each domain:
  == domain 1  score: 134.9 bits;  conditional E-value: 1.5e-43
      DUF676   3 kkdhLvVlvHGlqgn.saDlelikeqleki.......................keklpeekieflmsennesktfkgidvlgerlaeevlevvkkkkdk 77 
                    hLv+l+HGl++n +aD+ ++ke + ++                       +++ ++e ++++++ +n+++t+ gi++lg+rla++vl +++ ++  
  EEA19782.1 273 RRIHLVILTHGLHSNlGADMLYLKESIDAAaeeakrakkdstecqagsdhetrSDEEEDEEVIVRGFPGNVTRTERGIQYLGKRLAKYVLLMTYPDQPY 371
                 568*****************7777766666666667777777777887776656666777*****************************9887654444 PP

      DUF676  78 .................................nkkiSfvghSlGgliaraaiaklkekemtlkeaikglepvtfitlasPhLGvlysskslinlglal 143
                                                   + iSf+ghSlGgli+++aia+++++    +e+++ ++p++f++la+P+LG+  ++++        
  EEA19782.1 372 lptkkkkrknnpnsspgteidynpwdirpsdcqVTSISFIGHSLGGLIQTYAIAYIQKHS---PEFFERIKPINFVALATPFLGLSNENPV-------- 459
                 4555556789*********************99789*******************99654...579*************************........ PP

      DUF676 144 leklkkslsmeqlgltGrdLflk.........................ddkdeknsllykllkdekdlkliealklFkrrvlyanvvndrivplas 214
                   +++ +l+++ +g+tG+dL l                           ++  +++ l+++l   ++ +++   ++F++r++y+nvvnd+ivpl++
  EEA19782.1 460 --YVRFALDLGLVGKTGQDLGLSwmspkvrsrwdaiiskfagssspsqQEQAPASKPLLRILPAGPAHQVL---QRFRNRTVYSNVVNDGIVPLRT 550
                 ..*******************************************999888899999****9999955555...56******************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (998 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       595  (0.0331865); expected 358.6 (0.02)
Passed bias filter:                      440  (0.0245412); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.70u 0.30s 00:00:01.00 Elapsed: 00:00:00.44
# Mc/sec: 6760.57
//
Query:       EEA19783.1  [L=298]
Description: inositol monophosphatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.2e-65  221.8   0.0    1.4e-65  221.5   0.0    1.0  1  Inositol_P  Inositol monophosphatase family


Domain annotation for each model (and alignments):
>> Inositol_P  Inositol monophosphatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  221.5   0.0     8e-70   1.4e-65       2     267 ..      11     288 ..      10     294 .. 0.87

  Alignments for each domain:
  == domain 1  score: 221.5 bits;  conditional E-value: 8e-70
                 CHHHHHHHHHHHHHHHHHHHHHTTTSEEEESTTTCCHHHHHHHHHHHHHHHHHHHHHHHHSTTSEEEHHCHHHHCCCT.SSSSSEEEEEEEEETHHHHH CS
  Inositol_P   2 leevtkaavelaakagevlreefsenelvieekskegeedlvtaadeaveelilealaekfpshkilgeetlakgekseltedgltwivDPiDGTknFv 100
                 l+e+ ++ +e+a++ag+v++ +++ +  + +  sk+++ dlvt++d+ave+++ ++l++k+p+ ++ geet+++ +   lt++ +t+ivDPiDGT+nFv
  EEA19783.1  11 LREIHDVLIEIAFEAGKVITNSLP-TITSTD--SKKNSSDLVTEYDKAVEAMVSTRLKAKYPNYDFHGEETYSPDH--PLTDN-PTFIVDPIDGTTNFV 103
                 6889999****************9.444444..3458***************************************..9****.*************** PP

                 HT-SG-EEEEEEEETTEEEEEEEEETTTTEEECEETTTEEEETC.EEEEECTTS.....EGGGTEEEEEESSSSSSHHHHCHHHHHHHCCCCCH..... CS
  Inositol_P 101 rgipqvaVsigllvegkpvlGviaqPllgqlysaakgkGaflng.eklplsrap.....piseallvtlfavssrkdtseasllekvesavsae..... 188
                 +g+p  ++s+g++ + kpv+Gv+++ ++++lys+ kg+Gafln   +lpl++++     +  ++ l++l+++s+r+ ++    l+   s+ +++     
  EEA19783.1 104 HGFPSSCISLGFAIDRKPVVGVVYNAFTSTLYSGIKGQGAFLNRtTPLPLKQGDkletlDGLDKALIALEWGSERSGPNWDVKLKTFASLGKTReagga 202
                 ********************************************999******9999996666668899**********98888888877777799*** PP

                 ...EEEBESSHHHHHHHHHHTSTSEEEEEC.EBHHHHHHHHHHHHHTTEEEEESSSC.......SSSTTSSEEEEESCHHHHHHHHHHH CS
  Inositol_P 189 ...gvrsvgssalklaavaeGkadaylefgrekkWDhAAGeaileeaGGvvtdakge.......grlllargiiaanqkelaellaaav 267
                    ++rs+gs+al+++ava+G +d y+e g ++ WD++AG++ileeaGG+++  +++       gr++ a ++     ++ ++ l++++
  EEA19783.1 203 mvhSIRSLGSAALNICAVASGVLDLYWEGG-CWAWDVCAGWIILEEAGGIMVGGNQGdwtpaidGRVYTAVRPSP--DGKGQKELVEEL 288
                 ******************************.*********************99999555444444444433322..334444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (298 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       295  (0.0164538); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.46
# Mc/sec: 1960.23
//
Query:       EEA19784.1  [L=705]
Description: DNA-binding protein HGH1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.6e-69  231.6   0.1      7e-68  228.1   0.0    2.4  3  DUF383    Domain of unknown function (DUF383)
    1.7e-21   75.8   3.6    8.7e-21   73.5   3.1    2.6  2  DUF384    Domain of unknown function (DUF384)
    1.6e-12   47.5  35.1    5.7e-06   26.5  15.7    2.6  2  IBR       IBR domain, a half RING-finger domain
     0.0049   16.6   0.0     0.0085   15.8   0.0    1.4  1  DUF2158   Uncharacterized small protein (DUF2158)


Domain annotation for each model (and alignments):
>> DUF383  Domain of unknown function (DUF383)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       1.1   4.9e+03      73     111 ..     341     376 ..     336     397 .. 0.62
   2 !  228.1   0.0   1.6e-71     7e-68       1     189 [.     416     603 ..     416     604 .. 0.95
   3 ?    0.6   0.0     0.086   3.9e+02      42      69 ..     639     666 ..     605     672 .. 0.64

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 1.1
      DUF383  73 dylayvfanlsqlpegRelllepqesdkelplqkllpft 111
                  y+    anl+++ +    l +++   +  p++ l   +
  EEA19784.1 341 TYIDPAAANLTVFSSSQPTLFKKE---NLQPIKDLKILV 376
                 567777778888777777777775...345666555555 PP

  == domain 2  score: 228.1 bits;  conditional E-value: 1.6e-71
      DUF383   1 kildskslladlacmLLsNltkeesiaaqlleaklkvsqtpeessksvkalekLldlfvkgatkdlnksanydylayvfanlsqlpegRelllepqesd 99 
                 k++++++++ad ++mLL+Nl+k +s ++ ++  +l+++++ ++ s+s++al++Lld+fvkga+ +lnk anydylayvfa+ls+++egR++++++q++d
  EEA19784.1 416 KVTNKNEPNADDIAMLLANLAKADSFSR-II--SLTRKKA-DDVSTSTNALDQLLDCFVKGADGALNKAANYDYLAYVFADLSKTEEGRKFFTTKQDYD 510
                 689***********************99.66..5766664.5899****************************************************** PP

      DUF383 100 kelplqkllpftehksiirRgGvastiKNccFekeahklLlseee...vdllpylllpLagpeeldeedqekLpeelqllpedKeRepdsdir 189
                  ++p++kll+fteh+s irR+Gva tiKN+cF+ ++h++L+seee   ++llpy+llp++gpee+ +++++++ ++lqllp+dK+Re+d++i+
  EEA19784.1 511 GVIPVTKLLVFTEHTSDIRRRGVAWTIKNVCFDVQSHPMLISEEEdegANLLPYILLPIMGPEEYPDDESSEMLPDLQLLPPDKRRETDNQII 603
                 ******************************************866778*******************************************98 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.086
      DUF383  42 eessksvkalekLldlfvkgatkdlnks 69 
                  e+++  +a ++L++++++g++ ++n+ 
  EEA19784.1 639 VENEEVREACDRLVQVLMRGEEGEVNEA 666
                 23447778999*******9999999876 PP

>> DUF384  Domain of unknown function (DUF384)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0      0.81   3.6e+03       5      18 ..     493     506 ..     492     509 .. 0.78
   2 !   73.5   3.1   1.9e-24   8.7e-21       1      54 [.     609     662 ..     609     663 .. 0.98

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.81
      DUF384   5 LcatrhgReyLRsk 18 
                 L +t++gR+++  k
  EEA19784.1 493 LSKTEEGRKFFTTK 506
                 678*****998665 PP

  == domain 2  score: 73.5 bits;  conditional E-value: 1.9e-24
      DUF384   1 sLllLcatrhgReyLRskgvYpilRelhkaekdeeveeaierlVqvLirdEsee 54 
                 +LllL++tr+ R+ +R+++vYpi+Re+h a+++eev+ea++rlVqvL+r E++e
  EEA19784.1 609 TLLLLTTTREVRDKMRQVQVYPIIRECHSAVENEEVREACDRLVQVLMRGEEGE 662
                 8**************************************************975 PP

>> IBR  IBR domain, a half RING-finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.3  11.4   1.4e-09   6.5e-06      15      62 .]      57     112 ..      41     112 .. 0.75
   2 !   26.5  15.7   1.3e-09   5.7e-06      12      62 .]     124     170 ..     114     170 .. 0.83

  Alignments for each domain:
  == domain 1  score: 26.3 bits;  conditional E-value: 1.4e-09
         IBR  15 dpnlkwCprpdCeaiiekseg..cks......vtCskCgfefCfnCkkewHegl.sC 62 
                  +++ +Cp++ C+++i++s+     +       +Cs+C+ + C+ C+  wH++  +C
  EEA19784.1  57 AKDRYYCPSQRCGKWIKQSNVikD-QhgkpkyGRCSHCRIKVCCICRGRWHGSRgEC 112
                 45689***********87777652.134555588*****************975555 PP

  == domain 2  score: 26.5 bits;  conditional E-value: 1.3e-09
         IBR  12 lesdpnlkwCprpdCeaiieksegcksvtCskCgfefCfnCkkewHeglsC 62 
                 + +++ ++ C   +C++i+e ++gc+++tC+ C+ efC++C ++w   ++C
  EEA19784.1 124 MAKENGWQRCY--NCSSIVELKDGCNHMTCR-CKAEFCMRCAAKWKT-CDC 170
                 4455569***9..******************.*************85.555 PP

>> DUF2158  Uncharacterized small protein (DUF2158)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   1.9e-06    0.0085       4      41 ..     138     178 ..     135     191 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 1.9e-06
     DUF2158   4 dVVkLKsGGpeMTVtaaGgviaapg...eslkCqWFdgege 41 
                 ++V+LK G  +MT   ++++ +  +   +   C WF+ +  
  EEA19784.1 138 SIVELKDGCNHMTCRCKAEFCMRCAakwKTCDCPWFNHDVP 178
                 69*************9998877776656788999**98765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (705 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       727  (0.0405488); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.27s 00:00:00.90 Elapsed: 00:00:00.43
# Mc/sec: 4870.07
//
Query:       EEA19785.1  [L=703]
Description: transcription initiation factor IIF subunit alpha, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.6e-07   28.8  58.4    9.7e-07   27.7   9.9    2.9  2  TFIIF_alpha   Transcription initiation factor IIF, alpha subu


Domain annotation for each model (and alignments):
>> TFIIF_alpha  Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.7   9.9   5.4e-11   9.7e-07      94     190 ..     237     328 ..     179     342 .. 0.84
   2 !    3.5  45.8    0.0012        22     243     419 ..     318     517 ..     313     553 .. 0.48

  Alignments for each domain:
  == domain 1  score: 27.7 bits;  conditional E-value: 5.4e-11
                  CTTSXEEEEESSTTS..EEEEEEEXSSSSSSEEEEEEEEETTSEEEEEEEEEEEEEEEGGCSTXXSSTTTHHHHHHHXSSSXSHHHHHHXXXXXX.. CS
  TFIIF_alpha  94 lddqPWiLevggkeggqkkfrGireGgvsenasyyvltkapdgafeAypvneWynFnpvaryktLtleeAEeeferRkktlngfslmlkkalkkgea 190
                   ++ PW +e   +  +++ + G  e + se  + +vl     g+++  p+++Wy+F   + +ktLt+eeAE+ ++++ k    f   ++ a++++e 
   EEA19785.1 237 EEALPWHME---DFDNKNTWMGNYEAALSETYAMFVLES--TGKMRMVPIDKWYRFSARNAFKTLTIEEAEKFMSKKIKDPRWFMEKQQEAVRQKEL 328
                  4788****9...3334578**********7666666666..99*********************************999999999988888888765 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.0012
                  XXXXXXXXXXX.....XXXXXXXXXXXXX.XXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  TFIIF_alpha 243 Kkkkkaknkkk.ldddkkkkrgsdddadeydsddGddegrEld.yisDdsasendpeeredkkseEeeekkeieqdedeeekeeekkeeegklskkkk 338
                  K +++a  +k+ ++  k++k+   +++      dG+d + E+d + +D++ +    ee+ed+k+ E+  k+++ +++  + kee++ +ee+  +k++k
   EEA19785.1 318 K-QQEAVRQKElDAYAKQRKVYRGKEVSV-AGLDGNDMDFEEDrFADDEEVDAGLFEEDEDTKAAEQRIKQDQLKANVFNLKEEKDYDEEEMREKREK 413
                  4.667888888445555555555555555.56678888777772555555555567899999999999999988877666666666666666666666 PP

                  XXXXXXXXX........XXX..XX........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXX.. CS
  TFIIF_alpha 339 kakklkkkk........kekdkkd........SddeedsddsDideedsvslvkakKkkekkkeekvdsnessagnsrparpspeqkdskskrkaa.. 418
                  +a+k  +kk        +++ + +        Sd+e++++dsD ++e+     +++ +k  +ke++ +s+ s ++++ ++rp  ++    + +ka+  
   EEA19785.1 414 EARKVIGKKvrkalqrrEKNFDYSsgsdvnpySDEESSDEDSDAENEKEEDKKTEE-EKALAKEKEKESGASTKASTPSGRPKHTD----ALKKASgi 506
                  66555444411111110222122211111111233333333333333332221111.12223444444555555555555554443....33333334 PP

                  ........... CS
  TFIIF_alpha 419 ..........s 419
                            s
   EEA19785.1 507 grkrigspnlS 517
                  43334444332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (703 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1787  (0.0996709); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.95u 0.35s 00:00:01.29 Elapsed: 00:00:00.51
# Mc/sec: 4159.41
//
Query:       EEA19786.1  [L=2090]
Description: fatty acid synthase beta subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.7e-158  527.2   0.0   2.6e-158  526.6   0.0    1.3  1  DUF1729          Domain of unknown function (DUF1729)
    2.9e-90  303.0   0.0    6.8e-89  298.5   0.0    2.5  2  Acyl_transf_1    Acyl transferase domain
    4.9e-54  182.1   0.0    1.8e-53  180.3   0.0    2.0  1  FAS_meander      Fatty acid synthase meander beta sheet domai
    6.9e-40  137.3   0.0    1.7e-39  136.0   0.0    1.7  2  SAT              Starter unit:ACP transacylase in aflatoxin b
    2.6e-39  134.2   0.0    9.8e-39  132.3   0.0    2.0  2  FAS_N            N-terminal domain in fatty acid synthase sub
    7.8e-38  128.8   0.0    1.7e-37  127.7   0.0    1.6  1  MaoC_dehydratas  MaoC like domain
    3.8e-21   75.6   0.0    1.1e-20   74.2   0.0    1.8  1  MaoC_dehydrat_N  N-terminal half of MaoC dehydratase


Domain annotation for each model (and alignments):
>> DUF1729  Domain of unknown function (DUF1729)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  526.6   0.0    1e-161  2.6e-158       1     353 []     738    1087 ..     738    1087 .. 0.99

  Alignments for each domain:
  == domain 1  score: 526.6 bits;  conditional E-value: 1e-161
     DUF1729    1 piilqwtggraGGHHSledleaplletYakiRkqkNvvlvvGsGlgdaedsieyltGeWskelglppmPvdgillgsavmvakEaktseevkqlive 97  
                  p+ilqwtggr+GGHHS+ed+++p+l++Y++iRk++N+vlv+GsG+g +ed+++yltG+Ws+++g+ppmP+dg ++gs++m+akEa+ts ++k++i +
  EEA19786.1  738 PVILQWTGGRGGGHHSFEDFHQPILAMYSRIRKCSNIVLVAGSGFGGSEDTYPYLTGTWSSKFGYPPMPFDGCMFGSRMMTAKEAHTSLNAKKAIAA 834 
                  79*********************************************************************************************** PP

     DUF1729   98 tpGvkdeeWeatykkpaGgvvsvrSelgepihkianraaklwkeldetifsleavekrkaalekkrdeiierlnkdyakpwfavdeegelveleemt 194 
                  +pGv+d++We+ty+kp+Ggv++v Se+gepihk+a+r++ +w eld++if l +++kr+ +l+k+rd+ii++ln d++k+wf+ ++ ge+v+le+mt
  EEA19786.1  835 APGVDDAQWEQTYQKPTGGVITVLSEMGEPIHKLATRGVLFWSELDKKIFAL-DKAKRVPELKKNRDWIIKKLNDDFQKVWFGRNAAGETVDLEDMT 930 
                  ****************************************************.9******************************************* PP

     DUF1729  195 YsevvrRlveLaflksrkewidpswkklfqdllqrveeRltaeehgeaesllesvealedPaeavetllaaypsaeaqlltaeDvawflqlvqrrgi 291 
                  Y+evv+R+veL+++k++++wid+s+kkl+ d+++rve R+t+++   ++sll+++++l++P+ +v+++l ayp+a++ql++a+Dv++fl l+qrrg+
  EEA19786.1  931 YTEVVHRMVELMYVKHESRWIDESHKKLTGDFIRRVEGRFTSTD--GQASLLQNYSELNQPYPTVDKILSAYPEAATQLINAQDVQHFLLLCQRRGQ 1025
                  ****************************************6664..788999********************************************* PP

     DUF1729  292 KPvpFvPvldedfeaffkkdslwqsedldavvdqdaqrviilqgpvavryitkvdepvkeil 353 
                  KPvpFvP lde+fe++fkkdslwqsedl+av +qd+ r+ ilqgp+av+y+++vdep+keil
  EEA19786.1 1026 KPVPFVPSLDENFEFWFKKDSLWQSEDLEAVYGQDVGRTAILQGPMAVKYVNTVDEPIKEIL 1087
                  ************************************************************98 PP

>> Acyl_transf_1  Acyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0     0.072   1.8e+02      87     112 ..     282     307 ..     220     340 .. 0.76
   2 !  298.5   0.0   2.7e-92   6.8e-89       2     317 ..    1692    2064 ..    1691    2065 .. 0.96

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.072
                    EEE-TTHHHHHHHHCCSSSHHHHHHH CS
  Acyl_transf_1  87 vvGHSlGElAaavvagalsseealla 112
                      GHS+G + aa+ a+a + ee ++a
     EEA19786.1 282 TTGHSQGVVTAAAIAAAKTWEEFAKA 307
                    56*********999999998886665 PP

  == domain 2  score: 298.5 bits;  conditional E-value: 2.7e-92
                     EEE--TT---TTTTCCHHHC-HHHHHHHHHHHHHCCHHHT--HHHHHHS--T.......................................... CS
  Acyl_transf_1    2 fvfsGqGsQwaGMGmeLlktskafaaviaradeafksqygfsvldvlrnnpe.......................................... 53  
                     +vf+GqGsQ++GMGm+L+++s+++++v++rad++f ++ygfs+ d+++nnp+                                          
     EEA19786.1 1692 YVFTGQGSQEQGMGMDLYASSEVAKEVWDRADKHFLENYGFSIIDIVKNNPKeltiyfggprgkairqnymsmtfetvnadgsiksekifkevd 1785
                     9********************************************************************************************* PP

                     ............TGGGSHHHHHHHHHHHHHHHHHHHHHTT..-TTSEEEE-TTHHHHHHHHCCSSSHHHHHHHHHHHHHHHHHHTS-EECCEEC CS
  Acyl_transf_1   54 ............glldaiqfvqpaLaavqialaellkskG..vrpaavvGHSlGElAaavvagalsseeallavvlrsrlmmqlagpgdmaave 133 
                                 gll+a+qf+qpaL+++++a +e+++skG  +r+  ++GHSlGE++a+++++ ++++e+l++vv++++l+mq+a+++d+ +++
     EEA19786.1 1786 ektnsytyrspaGLLSATQFTQPALTLMEKASFEDMRSKGlvQRDSSFAGHSLGEYSALAALAEVMPIESLVSVVFYRGLTMQVAVERDEQGRS 1879
                     *****************************************999************************************************** PP

                     S.HHHHHHH..TT.EEEEEEECCCCECCEEHHHHHHHHHHHHHCC.CCEEECCCEECTTCCCCCCCCHHHHHHHHCCCHHCHHTTBEHCCCHHH CS
  Acyl_transf_1  134 laeeeeklrcqddvvgavansprrvvisgsqealrelvervskegvgalvenvnvavhspqvdaiadalasaladiaprkpkvakisstsldes 227 
                     +             + ++a +p+r+  +++++al++ ve++s+ + g+l e+vn++v + q++a++d +a++++++ ++  k +ki++  l + 
     EEA19786.1 1880 N-------------YSMCAVNPSRISKTFNEQALQYCVENISEVT-GWLLEIVNYNVANMQYVAAGDLRALDTLTNLLNVLKAQKIDIQALMQT 1959
                     *.............*******************************.*****************************************9999888 PP

                     .....HHHCHHHHHHHHHHHCHCCHCCHHTTS.SSECC-CCEECSSSSCCHCCCCCCCHH.......GGG-TCCCCCCTEETTSS-..HHHCHH CS
  Acyl_transf_1  228 .....serelsaeywvanlrspvrfaeavlsa.aetiplvfveispHslllaalektlks.......aedvksatlvGklkrdltd..flvtfl 306 
                          ++++l++++++  +    ++ + vl++ ++tipl ++++++Hs+ l+ ++k+++s       +  + + +l+Gk+++++t+  f  t++
     EEA19786.1 1960 msledVKEHLVQIIHECVKLTEAKPTPIVLERgFATIPLRGIDVPFHSTFLRSGVKPFRSfllkkinKTTIDPSKLIGKYIPNVTArpFEITKE 2053
                     45555556666666666666666666678999************************************************************** PP

                     HHHHHHHHCT- CS
  Acyl_transf_1  307 yllakahltgs 317 
                     y+ +++ ltgs
     EEA19786.1 2054 YFEDVYRLTGS 2064
                     *********97 PP

>> FAS_meander  Fatty acid synthase meander beta sheet domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  180.3   0.0   6.9e-57   1.8e-53       2     146 .]    1152    1296 ..    1151    1296 .. 0.99

  Alignments for each domain:
  == domain 1  score: 180.3 bits;  conditional E-value: 6.9e-57
  FAS_meander    2 selpseeewlellageelsWlralltsetivqgkklveNPlrrllaprkgqlveieeadspektvvtvkeakesgelkkaveiklsedkeIsvtli 97  
                   ++lp+ ++w+++lag+++sW++a++t+e++vqg+++ +NPl+rllap++g++vei ++++pekt+++v+e+++s++l+k+veik+ + keI++t++
   EEA19786.1 1152 ATLPDLDSWMQILAGRNYSWRHAFFTTEVFVQGQRFETNPLKRLLAPTRGMYVEIVSPEDPEKTIISVREPSQSSKLVKTVEIKMVGPKEIALTMF 1247
                   689********************************************************************************************* PP

  FAS_meander   98 eertaegesvpLeleFeYkpetglapIhEvmegrndrikeFYwklWfge 146 
                   e rtaeg+ +pL+++F+Y+petg+apI+Evme rndrikeFY++ Wfge
   EEA19786.1 1248 EGRTAEGTVIPLTFRFTYHPETGYAPIREVMEHRNDRIKEFYYRAWFGE 1296
                   ***********************************************97 PP

>> SAT  Starter unit:ACP transacylase in aflatoxin biosynthesis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  136.0   0.0   6.6e-43   1.7e-39       2     238 ..     172     424 ..     171     426 .. 0.88
   2 ?   -3.2   0.0       2.1   5.4e+03      92     129 ..    1818    1856 ..    1798    1881 .. 0.74

  Alignments for each domain:
  == domain 1  score: 136.0 bits;  conditional E-value: 6.6e-43
         SAT   2 lFGDq.tad.vlpeLrkLlqakenplLrsFLekasealraeisrlpaaerkslp...rf.tslqellerysesglkspalssallciaqlaqfivy... 91 
                 +FG+q + + +++eLr+++  ++ +++++++ + +e l+   +  p a +  +p   ++ ++l++  +++++++l s+++s++l++++qla+++v+   
  EEA19786.1 172 VFGGQgNIEeYFDELREVY-TTYPAFVEDLVSSTAELLQSLSR-DPDAVK-LYPkglDIlQWLHDRDSQPDTDYLVSAPVSLPLIGLVQLAHYMVTckv 267
                 8****97777*********.88999999988877777776655.454444.455678666************************************887 PP

         SAT  92 leenpeeypspestylvGlCtGllaAaavacskslseLvplaveavrvafrlGlevar...........vaarleegsssssesWslavtglseeelek 179
                 l+++p e+ ++  ++ +G+++G++ Aaa+a++k+++e+ ++a +a++++f++Gl++++            ++++e  + + + +++l++++l+++++++
  EEA19786.1 268 LGRQPGELLER-ISGTTGHSQGVVTAAAIAAAKTWEEFAKAAKDAITLLFWIGLRSQQayprtslapstLQDSIE--NGEGTPTPMLSIRDLQRAAVQE 363
                 79999999976.56********************************************99888886666666666..4444566*************** PP

         SAT 180 alaefneekglppasrvyisavssss.vtisGpPstl...eallksskakkkkkksklpiyap 238
                 +++++n++ +  + +++ is+v+s + ++++GpP +l   +  l++ ka + ++++++p++++
  EEA19786.1 364 HIDATNQHLP--QDRHIAISLVNSARnFVVTGPPISLyglNLRLRKVKAPTGLDQNRVPFTQR 424
                 *******998..89**********999************9********************987 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.1
         SAT   92 leenpeeypspestylvGlCtGllaAaav.acskslseL 129 
                  +e+ ++++  + ++  +G++ G  +A a+ a    +++L
  EEA19786.1 1818 FEDMRSKGLVQRDSSFAGHSLGEYSALAAlAEVMPIESL 1856
                  45555666666688999*****99997652544555555 PP

>> FAS_N  N-terminal domain in fatty acid synthase subunit beta
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.3   0.0   3.8e-42   9.8e-39       1     127 [.      20     145 ..      20     147 .. 0.92
   2 ?   -2.2   0.0       1.5   3.8e+03      27      69 ..     904     949 ..     898     973 .. 0.71

  Alignments for each domain:
  == domain 1  score: 132.3 bits;  conditional E-value: 3.8e-42
       FAS_N   1 slrplslthgslevsilvpaslylaaeqLrdeFtatlvapseeleqeeeplseieLlakFLgyvaksiestesstsqf.edvlklvleefessyLkknd 98 
                 slrpl+lthgsle+s+lvp+sl+++a+qL+d+F+a+l+ p++el+q++ep+s++eL+a++ g+va+++++ ++   ++  +vlk+vl+efe+++L++nd
  EEA19786.1  20 SLRPLILTHGSLEFSFLVPTSLHFQAAQLKDTFNASLPPPTDELAQDDEPSSVLELVARYVGHVAQEVDEGDQDAHPTnVEVLKVVLNEFERAFLRGND 118
                 89*******************************************************************76655555549******************* PP

       FAS_N  99 ihalvsnLpsettllakke.viraYykala 127
                 +ha+v  L    ++ akk  v++aYy+a+a
  EEA19786.1 119 VHAVVATLS---GISAKKIaVVKAYYAARA 145
                 *********...56666655********97 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.5
       FAS_N  27 eqLrdeFtatlvaps.eeleqeeeplseieLlakF..Lgyvaksie 69 
                 ++L+d+F++    ++  ++  + e+++  e + +   L yv+++  
  EEA19786.1 904 KKLNDDFQKVWFGRNaAGETVDLEDMTYTEVVHRMveLMYVKHESR 949
                 6899*****7776664777788899999999988744567776655 PP

>> MaoC_dehydratas  MaoC like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.7   0.0   6.8e-41   1.7e-37       2     122 ..    1547    1676 ..    1546    1677 .. 0.98

  Alignments for each domain:
  == domain 1  score: 127.7 bits;  conditional E-value: 6.8e-41
                       TCCCTTSEEEEEEEEEEE.........HHHHHHHHHHHT---GGGT-HHHHHHTTTSSSB--HHHHHHHHHHHHHHHHSTTEGGGEEEEEEE CS
  MaoC_dehydratas    2 fqnaigekvetekeitvt.........eadialyalvsgDlnpiHvdpefAkkagfggpIahGmltlaivaklveeelgdnvvarvgeikvr 84  
                       ++++i+++v++e++i+++         +a++++ya+vsgD+npiHv++ f+ +a+++g+I+hGm+++a+v++lve++++dn++ rv++++v 
       EEA19786.1 1547 NGSSIEQPVNFENPIPLSgktplelraPASNENYARVSGDYNPIHVSRVFSTYAKLPGTITHGMYSSAAVRSLVETWAADNNIGRVRSYHVN 1638
                       56789*************************************************************************************** PP

                       E-S--BTTCEEEEEEEEEEEEEEEEEEEEEEEEEEEEE CS
  MaoC_dehydratas   85 FtkpVlpgdtlkvelevvgkrdvrktkkvevtkevtee 122 
                        +++Vlp+d + v+le+ g++++rk++kvev+++ tee
       EEA19786.1 1639 LVGMVLPNDAIAVKLEHIGMIAGRKIVKVEVRNKDTEE 1676
                       *********************************99986 PP

>> MaoC_dehydrat_N  N-terminal half of MaoC dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.2   0.0   4.1e-24   1.1e-20       4     131 ..    1306    1429 ..    1304    1430 .. 0.93

  Alignments for each domain:
  == domain 1  score: 74.2 bits;  conditional E-value: 4.1e-24
  MaoC_dehydrat_N    4 GaefepvkaevereavrefakavgetnpayldeeaaraagyrsliaPptflivlatkap..ell.ealgidlsrllhgeqefey...hepir 89  
                       +a f++ + +v+++av +f++avg+t +a++++  +      +  aP++f+iv+++ka    ++ + +++dl +l+h+++ f++   +ep++
       EEA19786.1 1306 TAIFDGGRETVTAQAVADFVHAVGNTGEAFVNRPGQ------DTYAPMDFAIVVGWKAItkPIFpRRIDGDLLKLVHLSNGFRMvpgAEPLK 1391
                       6668999****************************8......9*************886664446999****************99999*** PP

  MaoC_dehydrat_N   90 aGDelttesriadvydkkgvGalefivvettvtnqrGepvat 131 
                       +GD l t+++i++v ++   +++++++v+ t+  ++G+p+++
       EEA19786.1 1392 VGDVLDTTAQINAVINQ---DSGKMVEVCGTIK-RDGKPIMH 1429
                       ****************9...68***********.******98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2090 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       601  (0.0335211); expected 358.6 (0.02)
Passed bias filter:                      572  (0.0319036); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 1.22u 0.32s 00:00:01.54 Elapsed: 00:00:00.52
# Mc/sec: 12144.07
//
Query:       EEA19787.1  [L=1859]
Description: fatty acid synthase alpha subunit FasA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      3e-77  258.8   0.0      8e-77  257.5   0.0    1.8  1  FAS_I_H          Fatty acid synthase type I helical domain
    3.1e-76  255.2   0.0    6.5e-76  254.2   0.0    1.6  1  Fas_alpha_ACP    Fatty acid synthase subunit alpha Acyl carri
    2.8e-22   79.5   0.0    5.1e-22   78.7   0.0    1.4  1  ketoacyl-synt    Beta-ketoacyl synthase, N-terminal domain
    1.9e-18   66.7   0.0    4.6e-18   65.4   0.0    1.6  1  ACPS             4'-phosphopantetheinyl transferase superfami
    6.7e-11   42.2   0.0    1.9e-10   40.8   0.0    1.8  1  Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
     0.0074   16.2   0.0      0.022   14.7   0.0    1.8  1  KR               KR domain


Domain annotation for each model (and alignments):
>> FAS_I_H  Fatty acid synthase type I helical domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  257.5   0.0   2.7e-80     8e-77       1     202 [.     325     526 ..     325     527 .. 0.99

  Alignments for each domain:
  == domain 1  score: 257.5 bits;  conditional E-value: 2.7e-80
     FAS_I_H   1 tkkqnelvrqqlevlaryLgvdseasereaaessaevaelqaeLdlweaEhgdeylkgikpiFdakKaRrydSaWNwarqdilklyydllqgrlkdvdr 99 
                 tk+q++l++qqle+ a yL+ d +a+++++++s +  ++lqa+Ldlw+ Ehgd y++gi p+Fd +KaR+ydS+WNwarqd+l++yyd+++g+lk vdr
  EEA19787.1 325 TKDQRALFKQQLEAIAHYLKLDLRAGDKAHLASVESSKALQAQLDLWQVEHGDVYASGIAPAFDSLKARIYDSSWNWARQDALSMYYDIIFGKLKAVDR 423
                 689************************************************************************************************ PP

     FAS_I_H 100 eiksrlqrilnRadenlvdlvqyllkkakassgekyaaakelgekllknarsalsaapvyvelseptaPrttidekGnieYeEvpragvqeledyveel 198
                 ei s++ ri+nR+++ l+d++qy+l+++++++ge+y++akelg++l++n+++ l +apvy++++ pt+P+ttid +Gni+YeEvpra+v++le+yv+++
  EEA19787.1 424 EIVSQCIRIMNRSNPLLLDFMQYHLDNCPTERGETYQLAKELGQQLFENCKEVLGHAPVYKDVAIPTGPQTTIDSRGNISYEEVPRASVRKLEHYVKQM 522
                 *************************************************************************************************** PP

     FAS_I_H 199 ksGs 202
                 ++G+
  EEA19787.1 523 AEGG 526
                 **97 PP

>> Fas_alpha_ACP  Fatty acid synthase subunit alpha Acyl carrier domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  254.2   0.0   2.2e-79   6.5e-76       1     162 []     136     297 ..     136     297 .. 0.99

  Alignments for each domain:
  == domain 1  score: 254.2 bits;  conditional E-value: 2.2e-79
  Fas_alpha_ACP   1 eDepvkavdivraivaqklkkkldevplsksikdlvgGkStlqNEilgdLqaEfgslpekaedlpleelaealqesfsGklGkqssslisrlvssk 96 
                    +D pv+a+divr++vaqklkk+l+++p+sk+ikdlvgGkStlqNEilgdL++Efgs+pek+ed+pl+el++++q++f+G+lGkqsssl++rlvssk
     EEA19787.1 136 DDVPVSATDIVRTLVAQKLKKSLADIPVSKAIKDLVGGKSTLQNEILGDLGKEFGSTPEKPEDTPLDELGASMQATFNGQLGKQSSSLVARLVSSK 231
                    69********************************************************************************************** PP

  Fas_alpha_ACP  97 mpggfnlaairkyLekrwglgpgrqdsvlllavtsePakRlgseaeAkafldsvvqkyakkagisL 162
                    mpggfn++a+rkyLe+rwglgpgrqd++llla+t+ePa+Rlgs+a+Aka+ld +++kya++agisL
     EEA19787.1 232 MPGGFNITAVRKYLETRWGLGPGRQDGALLLALTAEPASRLGSDADAKAYLDGIANKYAAHAGISL 297
                    ****************************************************************98 PP

>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.7   0.0   1.7e-25   5.1e-22      50     252 ..    1152    1362 ..    1138    1363 .. 0.83

  Alignments for each domain:
  == domain 1  score: 78.7 bits;  conditional E-value: 1.7e-25
                     STTEEE-BSS.EEE..STTEGGTTSTHHHHHHHCTS-HHHHHHHHHHHHHHHHHTS-HHTC.....TTGGEEEEEEESSTHHHHHHHHHHHTT. CS
  ketoacyl-synt   50 paraagkiktklggfldvddfdpeffgispreaeamdpqqrllleaawealedagltpeel.....dgsrvgvfiGvgagdyaalaaldedgs. 137 
                     ++ +ag+i+t          +d++ +g++++  +++dp++ ++l++++e l ++g+t+        + s+vg++iG+g g ++al+ +++d   
     EEA19787.1 1152 DRLVAGQIPT---------GWDAKRYGVPDDIIDQVDPVTLYVLVCTAESLLSSGITDPYEfykyvHLSEVGNCIGSGVGGTSALRGMYKDRYl 1236
                     5667777777.........799**********************************77666577766667**********99776666655544 PP

                     GGGSCTTHHHHHSTTHHHHHHHHH.HT--SSEEEEESGGGHHHHHHHHHHHHHHTTS-SEEEEEEEE---SHHHHHHHHHTTBB-TT.SG.... CS
  ketoacyl-synt  138 evkaspkavgavlanviagrisya.lglrGpsvtvdtACsSslvavhaavqslrsgeadvalaGGvellltpeavagfsaagllspd.gr.... 225 
                     ++ +  ++++    n++a+ +++  l  +Gp  +++ AC++s   ++  ++ +++g+a v+l+GG + ++++e+ + f+++g++s+  +     
     EEA19787.1 1237 DKPVQKDILQESFVNTMAAWVNMLlLSSTGPIKSPVGACATSVESLDIGYDTIVEGKARVVLVGGFD-DFQEEGSYEFANMGATSNAkEEfkrg 1329
                     34444456666899*********999*****************************************.99999999******777764334556 PP

                     ...GGTTBTTB...-SB-BB-EEEEEEEEECHH CS
  ketoacyl-synt  226 ...ckafdpka...dGfvlGEGvGavvLkrled 252 
                        +  ++p     +Gf+ ++G+G+ vL++++ 
     EEA19787.1 1330 rtpQDMSRPTSttrNGFMESQGCGIQVLMTAQL 1362
                     56655555555777**************98875 PP

>> ACPS  4'-phosphopantetheinyl transferase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.4   0.0   1.5e-21   4.6e-18       1     113 [.    1741    1854 ..    1741    1855 .. 0.89

  Alignments for each domain:
  == domain 1  score: 65.4 bits;  conditional E-value: 1.5e-21
                  EEEEEEEEHHHHH.HHH-----HHHHHS-HHHHHHHTT--HHHHHHHHHHHHHHHHHHHHHTTS-SSS.S--GGG-EEEE-TTS-EEEE-S-SSEEE CS
        ACPS    1 gvGiDieklsrlrkrvkrrgakilkrifteeErkllkssdeearaelfarlWaaKEAllKalgpglrk.lldfksievledstgrptlellseakkk 96  
                  +vG+D+e++++++     +++ +++r fte+E++++++++++++   fa+ W+aKEA++K+lg + +    ++k+ie+l d++g+p ++l++ a+  
  EEA19787.1 1741 QVGVDVEDVEAIN-I---ENDTFIERNFTEREQAYCRKAPSPQA--SFAGKWSAKEAVFKSLGVQSKGaGAPLKDIEILADANGVPVVTLHGSAAEA 1831
                  59*****777777.4...8999*********************9..****************9998445**************************99 PP

                  EEEEE-..........SSEEEEE CS
        ACPS   97 awkleslkid......kdyviav 113 
                  a   ++++++      ++ +iav
  EEA19787.1 1832 AKLAGVKSVNvsishsDSQAIAV 1854
                  99999988887777777777766 PP

>> Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.8   0.0   6.3e-14   1.9e-10      30     117 ..    1495    1584 ..    1466    1585 .. 0.88

  Alignments for each domain:
  == domain 1  score: 40.8 bits;  conditional E-value: 6.3e-14
                       HHHHHHHHT--GGGEEEEE-SS-SSHHHHHHHHHHHHHHHGGGGG..SCTSEEE-THHHH-B-GGGHHHHHHHHHHHHHHHTEE--BTT- CS
  Ketoacyl-synt_C   30 iekalaeagvdpedvdyveahgtgtplgDpiElealkkvfgekar..kqplavgSvKsniGHleaAaGvaelikvvlalkhgvipptlnl 117 
                       ++ ala+ g++ +d d+ + hgt+t ++D++E   + + + + +r   + +    +K ++GH ++AaG+  +  ++++l+ g +p + n 
       EEA19787.1 1495 LRGALATWGLTIDDLDVASFHGTSTVANDKNESDVICQQLTHLGRkkGNAVLGIFQKYLTGHPKGAAGAWMMNGCLQVLNSGLVPGNRNA 1584
                       789**********************************9999999975333333469******************************9986 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   7.4e-06     0.022       4      79 ..     651     728 ..     649     743 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 7.4e-06
                 EEET.TTSHHHHHHHHHHHHHHS-EEEEE-SS...--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHS CS
          KR   4 litG.GlGgLGlelarwlaekgarhlvllsRsa.aadedskaliaelealgaevevvaaDvsdkdavealleeikaee 79 
                 l+tG G+G++G  + + l++ ga+ +v +sR + +++e  +++ a+  a+g +  vv+    +k++veal++ i +++
  EEA19787.1 651 LMTGaGAGSIGADVLQGLISGGAKVVVTTSRFSrEVTEYYQSMYARYGARGSQLVVVPFNQGSKQDVEALVDYIYDSK 728
                 6788579************************7537788889999***************************9987766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1859 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       741  (0.0413297); expected 358.6 (0.02)
Passed bias filter:                      530  (0.029561); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.10u 0.33s 00:00:01.43 Elapsed: 00:00:00.53
# Mc/sec: 10584.74
//
Query:       EEA19788.1  [L=1084]
Description: N2,N2-dimethylguanosine tRNA methyltransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.7e-113  379.6   0.0      1e-99  334.3   0.0    2.1  2  TRM            N2,N2-dimethylguanosine tRNA methyltransferase
    1.1e-38  132.2   4.1    5.8e-29  101.0   2.4    2.5  2  DUF1691        Protein of unknown function (DUF1691)
    1.1e-05   25.3   0.0    1.9e-05   24.5   0.0    1.3  1  Met_10         Met-10+ like-protein
  ------ inclusion threshold ------
        0.2   11.2   0.0        0.4   10.2   0.0    1.4  1  MTS            Methyltransferase small domain


Domain annotation for each model (and alignments):
>> TRM  N2,N2-dimethylguanosine tRNA methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  334.3   0.0  2.3e-103     1e-99      14     317 ..     427     838 ..     411     847 .. 0.91
   2 !   43.3   0.0   6.1e-15   2.7e-11     313     376 .]     878     939 ..     849     939 .. 0.89

  Alignments for each domain:
  == domain 1  score: 334.3 bits;  conditional E-value: 2.3e-103
                 --TT--SS--GGGHHHHHHHHHH...HHHHHHHH-S-.............................................................. CS
         TRM  14 vskkeeVFYNPvqefnRDlsvlvirqlellkkklgek.............................................................. 50 
                 ++++  VFYNP+q+fnRDlsvl+i+ ++  +  l ++                                                              
  EEA19788.1 427 FEQQVSVFYNPIQQFNRDLSVLAIKVFAKHHVALIQQqnankklrrkkakgkkrkredgeetlgaggeeggevtkkhhgdgqeqgadeivsavvppete 525
                 88999*******************9555555444444488889******************************************************** PP

                 ...........EEEEESS-TTSHHHHHHHHH-S-EEEEEEE-S-HHHHHHHHHHHHHTT--GGEEEE-S-HHHHHC..........--SS-EEEEEE-- CS
         TRM  51 ...........ikvldaLsasGlRaiRfalEvpgvkevlaNDisekAvelikeNvklneveeivvineddAnvlla..........ekkkrfdviDlDP 128
                            +++ldaLsa+GlRa+R+a+E+p++ +++ ND+s  Ave ik N+k+neve+iv +n +dA++ ++           + k+f+viDlDP
  EEA19788.1 526 adpasttkpvkFQILDALSATGLRALRYAKEIPEATRIVSNDLSAAAVEAIKLNIKYNEVENIVRPNVGDARAYMYslqgennandGNGKKFNVIDLDP 624
                 ****************************************************************************9*999988777889********* PP

                 SS--GGGHHHHHHHEEEEEEEEEEE--HHHHTT.SSHHHHHHHHSSB---STTHHHHHHHHHHHHHHHHHHTTTEEEEEEEEEEETTEEEEEEEEEE-H CS
         TRM 129 fGspapfldsavqsvkekglLlvTaTDtavLaG.aspekclrkYgavalkselcHEvalRillkavareaakYekavepllslsadfYvrvfvkvktga 226
                 +Gs+  fld+avq+v+++g+L+vT+TD av a   +pek ++ Yg+ +++    HEv+lR++l+a+a++aakY   vepllsls+d+Y rvfv+v++++
  EEA19788.1 625 YGSAGMFLDAAVQAVNDGGMLCVTCTDAAVFAStGYPEKTYALYGGIPVRLPHGHEVGLRLILHAIASAAAKYGLSVEPLLSLSIDYYARVFVRVHKSP 723
                 ********************************989**************************************************************** PP

                 HHHHHHHTTEEEEEEE.TTT...............--EEEE--GGG--.................SB-TTT-SBEEEEEEEE-S-S--HHHHHHHHHHH CS
         TRM 227 akvkkvleklglvlhC.sgC...............lseekvkglakfk.................aecehcgaklhlaGPlwlgplkdkefveevleea 292
                 ++vk++ + ++l++ C sgC               +           k                   cehcg k+hlaGP+w gpl++ +f++++l+ +
  EEA19788.1 724 IEVKALSSTTMLMYSCdSGCgawttqyltntkvktA-----------KdghvhtnyclgqapttsPCCEHCGFKTHLAGPMWGGPLHNPDFIQKILDLI 811
                 ****************77899887776544433321...........13335566777788887799******************************** PP

                 CT..-TTS..-HHHHHHHHHHHHHHS- CS
         TRM 293 ekekeeel..kkrvkklLklikeElld 317
                  + +++++    r++++L+++ eE ld
  EEA19788.1 812 PEVDPKTYrtLYRIEGMLTTALEEDLD 838
                 **9988886678************776 PP

  == domain 2  score: 43.3 bits;  conditional E-value: 6.1e-15
                 HHHS--SS-EEHHHHHHHHT-SS---HHHHHHH....TT-EE-TTSTTEEE-SS-HHHHHHHHH CS
         TRM 313 eElldaplyydlsqlasvlklsvpplkkvvsalkelgfevsrtHakpkaikTnapleavvevlr 376
                  E  + p++ +ls+la+vl++++ p + ++ al+ lg++++r+H++p++++T+ap+++++e++r
  EEA19788.1 878 RE--KYPFFVSLSALAKVLHTQTVPINLFRGALHGLGYRTTRSHTRPNSVRTDAPWDVLWEIMR 939
                 45..789*******************************************************97 PP

>> DUF1691  Protein of unknown function (DUF1691)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.4   0.0   1.1e-10     5e-07       1      83 [.      88     168 ..      88     181 .. 0.78
   2 !  101.0   2.4   1.3e-32   5.8e-29       1     105 [.     186     308 ..     186     310 .. 0.95

  Alignments for each domain:
  == domain 1  score: 30.4 bits;  conditional E-value: 1.1e-10
     DUF1691   1 pllglHvlvnrivPllv.gdsskvgllyvahglarspplslleyaaLvgsgvlHivsGlakwlgllrilkki.......kkkkrrrrwlii 83 
                 ++++lH++++ ++Pl     ss++ +l + + +++sp l   e +++   +v+Hi+sG+a     lr +++        +  +rr+++++i
  EEA19788.1  88 VFFALHAVNTSLIPLATrSLSSSDSFLLLTRPIYQSPSL---EPVMVALPIVAHIASGIA-----LRSIRTRrrakkygA--ERRSQRYLI 168
                 59***************99*******************9...******************.....432222222233232..333333555 PP

  == domain 2  score: 101.0 bits;  conditional E-value: 1.3e-32
     DUF1691   1 pllglHvlvnrivPllv.gdsskvgllyvahglarspplslleyaaLvgsgvlHivsGlakwlgll...............rilkki..kkkkrrrrwl 81 
                 pllglHv vnr++Pl   g+ss+vgl+yvahg+arsp++++l y ++v+++v+H+v+Gla+w+g++               +il+++  ++ krrr+++
  EEA19788.1 186 PLLGLHVGVNRVIPLGIdGGSSSVGLGYVAHGFARSPVFWNLFYFLFVATSVWHLVGGLATWMGIRvttirtergsisktaGILGETreERDKRRRNKW 284
                 799**********************************************************************998888887777779989999999** PP

     DUF1691  82 iingiaaakaalglaGglgvvkrg 105
                 +++gia ++aa++laG+lg+v+r+
  EEA19788.1 285 LVHGIAGLTAAVWLAGALGIVGRA 308
                 *********************997 PP

>> Met_10  Met-10+ like-protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.5   0.0   4.1e-09   1.9e-05     121     198 ..     557     646 ..     538     647 .. 0.82

  Alignments for each domain:
  == domain 1  score: 24.5 bits;  conditional E-value: 4.1e-09
                 HTTSSEEEEEES-HHHHHHHHHHHHHTT-TTCEEEEES-GGG---TT-EE...........EEE.E--TTTGGGGHHHHHHHEEEEEEEE CS
      Met_10 121 yskakrvlaidlnPesvkylkeniklNkvekvvkpileDgrevireqlad...........rvv.mnlpksaieFldkvlaalkdggvih 198
                   +a r++++dl  ++v+ +k nik N+ve++v+p  +D+r ++ + + +            v+ ++   sa  Fld++++a++dgg+ +
  EEA19788.1 557 IPEATRIVSNDLSAAAVEAIKLNIKYNEVENIVRPNVGDARAYMYSLQGEnnandgngkkfNVIdLDPYGSAGMFLDAAVQAVNDGGMLC 646
                 357899************************************9985555556779***998555355667999*************9988 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   8.9e-05       0.4      33      84 ..     537     589 ..     529     601 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 8.9e-05
                 SEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGCEEE CS
         MTS  33 gkvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenleanklevev 84 
                  ++lD  + +G+ ++  ake pea+ ++  d +a+A+e+ k n++ n++e  v
  EEA19788.1 537 FQILDALSATGLRALRYAKEIPEATrIVSNDLSAAAVEAIKLNIKYNEVENIV 589
                 5789999999*************999**********************98333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1084 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       566  (0.031569); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.80u 0.28s 00:00:01.08 Elapsed: 00:00:00.47
# Mc/sec: 6970.16
//
Query:       EEA19789.1  [L=216]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
     0.0037   17.7   1.2     0.0071   16.7   1.2    1.5  1  zf-C2H2      Zinc finger, C2H2 type
     0.0061   16.9   0.3      0.011   16.2   0.3    1.4  1  zf-met       Zinc-finger of C2H2 type
  ------ inclusion threshold ------
      0.019   15.3   1.9      0.029   14.7   1.9    1.3  1  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
      0.022   15.6   0.4      0.046   14.6   0.4    1.5  1  Rotamase_2   PPIC-type PPIASE domain
      0.035   14.2   0.3       0.13   12.4   0.0    1.9  2  DUF3592      Protein of unknown function (DUF3592)
      0.073   13.4   0.2       0.11   12.8   0.2    1.2  1  zf-C2H2_2    C2H2 type zinc-finger (2 copies)
      0.084   12.8   0.1       0.15   12.0   0.1    1.4  1  zf-LYAR      LYAR-type C2HC zinc finger
      0.092   13.6   0.5       0.21   12.5   0.5    1.6  1  zf-C2H2_4    C2H2-type zinc finger


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   1.2   3.2e-06    0.0071       1      20 [.      23      42 ..      23      47 .. 0.91

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 3.2e-06
                EEETTTTEEESSHHHHHHHH CS
     zf-C2H2  1 ykCpdCgksFkrksnLkrHi 20
                ++C+ C+ks++r  ++++Hi
  EEA19789.1 23 FTCTLCNKSYSRHPEYEAHI 42
                89*****************9 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.3   4.7e-06     0.011       1      20 [.      23      42 ..      23      44 .. 0.93

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 4.7e-06
      zf-met  1 fyCelCnvtfnsesqlksHl 20
                f+C lCn++++    +++H 
  EEA19789.1 23 FTCTLCNKSYSRHPEYEAHI 42
                89*****************7 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   1.9   1.3e-05     0.029       2      27 .]      23      50 ..      22      50 .. 0.91

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.3e-05
                 CBBTTTTBBBSSHHHHHCCTTS..HHHH CS
  zf-C2H2_jaz  2 fYCvlCdKyFksenaldnHlkS..KkHK 27
                 f C lC+K ++ +  +++H+ S  ++H+
   EEA19789.1 23 FTCTLCNKSYSRHPEYEAHIGSydHQHR 50
                 99******************88888886 PP

>> Rotamase_2  PPIC-type PPIASE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.4     2e-05     0.046      10      93 ..      38     161 ..      36     169 .. 0.63

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 2e-05
  Rotamase_2  10 Yeankdefskpegktle...lavvkdqvaaeaalalakagaekdfaalakgnskkaadlgifesa.................snlpe............ 76 
                 Yea++ +++ + +k+l+   ++  ++ +a  a++a+ ka+ae+ +  +  gns + a++   + a                 +                
  EEA19789.1  38 YEAHIGSYDHQHRKRLQdlkQLSRDPNAAERARKAERKADAEAGLVRVDPGNSSTSATTVTGSTAggggfkkggfkssfttvK---Gpaasamstaapv 133
                 ********999997777666666667777777788888888888999888888775554422222344444444444444430...1444455555556 PP

  Rotamase_2  77 ...........elakaafalkpgevsgp 93 
                            ++ + ++++++ +vsgp
  EEA19789.1 134 rknvlggddddDVGDVIDNTNKPNVSGP 161
                 6677777777777777777777777776 PP

>> DUF3592  Protein of unknown function (DUF3592)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0      0.49   1.1e+03      98     111 ..      80      93 ..      27     131 .. 0.55
   2 ?   12.4   0.0   5.6e-05      0.13      81     109 ..     167     201 ..     153     215 .. 0.70

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.49
     DUF3592  98 avqvyynPsnPtqa 111
                 a  v+++P n + +
  EEA19789.1  80 AGLVRVDPGNSSTS 93 
                 44566666665554 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 5.6e-05
     DUF3592  81 gsdn......vgdyaaqlyraGnavqvyynPsnPt 109
                 gsd+      v +    +yr G+a q+yy+P +Pt
  EEA19789.1 167 GSDSrklgtdVESDTDDEYRNGDAEQAYYDPLKPT 201
                 444444444444555555****************8 PP

>> zf-C2H2_2  C2H2 type zinc-finger (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.2     5e-05      0.11      47      79 ..      20      51 ..      12      63 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 5e-05
   zf-C2H2_2 47 ieekleClyCekefkslealreHmkkkgHckin 79
                +++ ++C +C+k+ +   ++++H+ + +H+  +
  EEA19789.1 20 LNS-FTCTLCNKSYSRHPEYEAHIGSYDHQHRK 51
                555.9*******************999998764 PP

>> zf-LYAR  LYAR-type C2HC zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.1   6.5e-05      0.15       1      18 [.      23      41 ..      23      43 .. 0.96

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 6.5e-05
     zf-LYAR  1 fsCiDCsktFdg.deykaH 18
                f+C  C+k++++  ey+aH
  EEA19789.1 23 FTCTLCNKSYSRhPEYEAH 41
                9***********9****** PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.5   9.5e-05      0.21       1      20 [.      23      42 ..      23      45 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 9.5e-05
   zf-C2H2_4  1 fkCpiCgksFsskkaLlrHl 20
                f+C++C+ks+s++ ++  H+
  EEA19789.1 23 FTCTLCNKSYSRHPEYEAHI 42
                89********9999999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (216 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       574  (0.0320152); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1447.40
//
Query:       EEA19790.1  [L=376]
Description: pyruvate dehydrogenase E1 beta subunit PdbA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.8e-47  161.3   0.0    5.3e-47  159.8   0.0    1.7  2  Transket_pyr     Transketolase, pyrimidine binding domain
    2.2e-35  121.3   0.1    6.9e-35  119.6   0.0    1.9  2  Transketolase_C  Transketolase, C-terminal domain


Domain annotation for each model (and alignments):
>> Transket_pyr  Transketolase, pyrimidine binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  159.8   0.0   5.9e-51   5.3e-47       2     176 ..      49     224 ..      48     226 .. 0.98
   2 ?   -1.6   0.0       0.2   1.8e+03      20      45 ..     337     362 ..     325     368 .. 0.79

  Alignments for each domain:
  == domain 1  score: 159.8 bits;  conditional E-value: 5.9e-51
                   EEEHHHHHHHHHHHHHCTTTTEEEEESSTH..HHHTTCHCCHHEGGTTEGEEE--S-HHHHHHHHHHHHHHCTTEEEEEEEEHHHHGGG..HHGGHH CS
  Transket_pyr   2 kiawrkaeaealaellkedpevvligaDva..ggtfsvrkgllhdqgegrvidsgisEqavlgfavGaalagpllviveaqFgdFangA..qiyadq 94 
                   ++++r+a++ealae+l+ +++v+++g++va  +g ++v+ gll+ +g++rvid++i+E++++g avGaalag l +++e++ ++Fa++A  qi++++
    EEA19790.1  49 EVTVRDALNEALAEELESNEKVFVMGEEVAqyNGAYKVTRGLLDRFGPKRVIDTPITEAGFTGLAVGAALAG-LHPVCEFMTFNFAMQAidQIINSA 144
                   6899**************************99****************************************.9*********************** PP

                   HHHCHHHHHT--EEEEESBSGGGSTTGTTTSBSSHHHHHHTSTTEEEE--SSHHHHHHHHHHHHHSSS.SEEEEEE-SSEEC CS
  Transket_pyr  95 airsgeakgklkvgvvtrlpigvgedGpehqsaeleaflrlipglkvvrPsdpaetkhllrrairredrkPvvlrlpksllr 176
                   a+++++++g +++++++r p g+    ++++s+   a++ +ipglkvv+P +++++k+ll++ ir  d++Pvv+++++ l+ 
    EEA19790.1 145 AKTHYMSGGIQPCNITFRGPNGFAAGVAAQHSQDYSAWYGAIPGLKVVAPWSAEDAKGLLKASIR--DPNPVVFLENELLYG 224
                   *****************************************************************..99********99986 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.2
                   TTTEEEEESSTHHHHTTCHCCHHEGG CS
  Transket_pyr  20 dpevvligaDvaggtfsvrkgllhdq 45 
                    p v+++gaDv      + +++ ++q
    EEA19790.1 337 APAVRVTGADVPTPYAQKLEEMSFPQ 362
                   5789******9988777777777776 PP

>> Transketolase_C  Transketolase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0      0.46   4.1e+03      68      87 ..      44      63 ..      38      79 .. 0.74
   2 !  119.6   0.0   7.7e-39   6.9e-35       1     124 []     243     366 ..     243     366 .. 0.99

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.46
                     EEEESTTSHHHHHHHHHHHC CS
  Transketolase_C 68 eeavkrgGigsevaaalaee 87
                      ea+k++ + +++++alaee
       EEA19790.1 44 SEASKEVTVRDALNEALAEE 63
                     57777777777777777774 PP

  == domain 2  score: 119.6 bits;  conditional E-value: 7.7e-39
                      TEEEEEETTSSEEEEEETTHHHHHHHHHHHHHTT.TTCEEEEE-SEEESHHHHHHHHHHHHHSEEEEEEEEESTTSHHHHHHHHHHHCCCTTCS CS
  Transketolase_C   1 gkaeilregkdvtlvayGsmveealeAaeeLeke.gisaeVvdlrtvkplDketilesvkktgrlvvveeavkrgGigsevaaalaeeafdgld 93 
                      gka+i+r+gkd+t+v+ ++ v  +l+Aa++L+++ g++aeV++lr+vkplD eti +s+kktgr++ ve + ++ G++se++a+ +e +fd+l 
       EEA19790.1 243 GKAKIERSGKDLTIVTLSRCVGLSLQAAADLKEKyGVEAEVINLRSVKPLDVETIIKSLKKTGRFMAVESGFPMYGVSSELLAVAMEYGFDYLT 336
                      89*******************************9************************************************************ PP

                      SEEEEEEE-SSSSSSGHHHHHHHTT-SHHHH CS
  Transketolase_C  94 apvkrvggpdviepgsaeelekafgldaeki 124
                      ap +rv+g dv++p++ ++le++  ++++ i
       EEA19790.1 337 APAVRVTGADVPTPYA-QKLEEMSFPQPDTI 366
                      ****************.99*********987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (376 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       456  (0.0254337); expected 358.6 (0.02)
Passed bias filter:                      434  (0.0242066); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2612.58
//
Query:       EEA19791.1  [L=611]
Description: Ser/Thr protein phosphatase family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.1e-12   46.1   3.0    8.8e-12   45.9   1.2    1.9  2  Metallophos    Calcineurin-like phosphoesterase
  ------ inclusion threshold ------
      0.017   15.3   0.0      0.062   13.5   0.0    1.8  2  5_nucleotid_C  5'-nucleotidase, C-terminal domain


Domain annotation for each model (and alignments):
>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.9   1.2   9.9e-16   8.8e-12       2     203 ..      42     266 ..      41     267 .. 0.69
   2 ?   -1.1   0.0      0.25   2.3e+03     100     172 ..     311     357 ..     280     380 .. 0.52

  Alignments for each domain:
  == domain 1  score: 45.9 bits;  conditional E-value: 9.9e-16
                  EEEEEESBTB...........TTCCTHHHHHHHHHHHHHHHTTESEEEEE.ST......SSSSSHHHHHHHHH.HHHHHHHTSEEEEEC-TTS..... CS
  Metallophos   2 rilvigDlHl...........algggqlddllkllddllreekpdlvlla.GD......lvdrgdlekellel.laalvkypipvylllGNHe..... 75 
                  ++l+++D+H+           +   g++ +++  +++++++++ dl+++  GD      l+d +d+  ++l+  l++         l  GNHe     
   EEA19791.1  42 NFLHTTDTHGwlaghlqepsySADWGDYVSFASHMREIAESQGSDLLVIDtGDrvegngLYDASDPKGKYLYEiLKQQHI----DLLSSGNHElykkn 135
                  79*******************9999*************9999******999**555555555555555555553555555....29999****77777 PP

                  ...........CHHHHHHHHHHHHHHH.HHHHEHHHCEEETSEEEEEETTE....EEEEEEESECEEETHHHHHHHHHHHSCHHHHCC.HHHHHHHHH CS
  Metallophos  76 ...........gfeeellnkygylgif.sepwrsdaevfnnlplaslgsgs....lkvlllhGgspellvsldklgslnleleapepg.dewlkdlek 156
                             gf++++  ++ ++    s++    +  f  l   +   g+    + +l+++ g      + ++    + ++ +++   + w+++  +
   EEA19791.1 136 tsdaeflttvpGFRDSYIASNIDIIDPrSGDLVPLGPRFRKLTTKV--QGYrimaFGFLFDFTG------NYNNT---KVQRVEDT-VkETWFQEAIR 221
                  7777777777655553333333333333444444455554444444..2223344678888888......22222...22222222.23789999999 PP

                  HTTCSEEEEEESSESSCSSSCSCCHHHHHHHHHHTTESEEEE.ESSSS CS
  Metallophos 157 rekadwvivlgHsplyrgsgylfgdealedllkkygvdlvis.GHtHv 203
                   e+ d  ivlgH+p+  + +y    ++++    ++++ + ++ GH H 
   EEA19791.1 222 DEDIDLFIVLGHVPVR-SEEYEAVHREIR--NVRGNITIQFFgGHLHI 266
                  9***************.888888888888..669999997666***96 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.25
                  CEEETSEEEEEETTEEEEEEEESECEEETHHHHHHHHHHHSCHHHHCC.HHHHHHHHHHTTCSEEEEEESSESS CS
  Metallophos 100 evfnnlplaslgsgslkvlllhGgspellvsldklgslnleleapepg.dewlkdlekrekadwvivlgHsply 172
                  + f+++   +l ++   ++++hG                        +  +++++  +r   d ++v+g  p  
   EEA19791.1 311 NLFSYYHHTGLNET--SFQTDHGR-----------------------NvSQMIQQ--ARHALDLDFVHGCAPKD 357
                  23333333333333..44444444.......................04556666..66666666666666655 PP

>> 5_nucleotid_C  5'-nucleotidase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0      0.39   3.5e+03      77     114 ..     108     156 ..     106     186 .. 0.67
   2 ?   13.5   0.0   6.9e-06     0.062      34      68 ..     390     424 ..     360     460 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.39
                    EHHHHHHHHHH...........HTTTTTS--TT-EEEE.SEEEEE-TTS CS
  5_nucleotid_C  77 tGaqlkeaLen..........esvsaskaasgrflqvs.Glrytydlsk 114
                    +G+ l e+L++           + +++++++ +fl +  G+r  y +s+
     EEA19791.1 108 KGKYLYEILKQqhidllssgnHELYKKNTSDAEFLTTVpGFRDSYIASN 156
                    7999999999888888888876667777777778755556665555554 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 6.9e-06
                    STT--EEEEEGGG----BTTTEEEHHHHHHHS-S- CS
  5_nucleotid_C  34 aagadialangggiradlpaGditvkdlltvlpfg 68 
                    a +  +a++n g+ir+d+++G+ t++  + v pf 
     EEA19791.1 390 AGKSAFAIVNTGAIRFDIFKGPFTQDSTFIVSPFT 424
                    444569****************************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (611 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       403  (0.0224776); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.23s 00:00:00.77 Elapsed: 00:00:00.39
# Mc/sec: 4663.77
//
Query:       EEA19792.1  [L=421]
Description: mitochondrial enoyl reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.4e-16   59.0   0.0    7.4e-16   58.3   0.0    1.3  1  ADH_zinc_N  Zinc-binding dehydrogenase
     0.0036   17.2   0.0      0.009   15.9   0.0    1.8  1  ADH_N       Alcohol dehydrogenase GroES-like domain


Domain annotation for each model (and alignments):
>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.3   0.0   8.2e-20   7.4e-16       1     120 [.     226     356 ..     226     369 .. 0.87

  Alignments for each domain:
  == domain 1  score: 58.3 bits;  conditional E-value: 8.2e-20
                 HHHHHHHHHHHHTT-EEEEEESSHHHHHHHHHT.......TESEEEET....TTCHHHHHHHHHT..TTSSEEEEEESSCSHHHHHHHHHCEEEEEEEE CS
  ADH_zinc_N   1 gvGlaavqlAkalGaeviavdsseeklelakkl.......Gadeviny....keadlverikelt..ggegvdvvfecvGsgatleaalkllkpgGrlv 86 
                 gvG aa+qlA+ +G+++  v +++e+le  + l       Ga++v+++    ++ ++   +k+lt  g++++ ++++cvG g+  +a  k+l+p+  lv
  EEA19792.1 226 GVGRAAIQLARVWGIKTLNVIRQRENLEETEALkkdllnlGATAVVTEaellSK-EFRGIVKQLTndGKQPIRLALNCVG-GENASAMAKVLAPDSHLV 322
                 8**************************7777777777888********888744.5888888888554899*********.****************** PP

                 ECSC.TSSEEEEEHHHHHHTT-EEEEE-SSCHHHH CS
  ADH_zinc_N  87 vvGg.gkgeeefdlrnlllkeksilGsllgslree 120
                 ++G+ + ++  ++ + l++k++ + G+++++ + +
  EEA19792.1 323 TYGAmSRKPVALPSGLLIFKNLVFDGFWVSR-WGD 356
                 ****6666666******************99.444 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0     1e-06     0.009       3      65 ..      89     160 ..      87     190 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 1e-06
                 EEEEEEEEEEE-HHHHHHHTTS........TTTTSSSS.EE---EEEEEEEEESTT-CS--TT-EEEE-SEE CS
       ADH_N   3 evlikvkaagiCgsDlhilkgg........kelevklp.lilGHEivGeveevgpevkklkvGdrVvvepli 65 
                 +v +++ a+ ++  D+  ++g         + l ++ p  i G E + ev ++gp+v++lk+Gd Vv++ + 
  EEA19792.1  89 QVNLRLLACPLNPADINQIQGVypakpaftNILGTAEPtAIGGNEGAFEVLSTGPQVQSLKKGDWVVMKRTG 160
                 68888899999999999999887887777744444444377789***********************98765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (421 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      451  (0.0251548); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.23s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 3115.60
//
Query:       EEA19793.1  [L=516]
Description: glutamyl-tRNA amidotransferase, A subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   6.7e-118  394.5   0.3   8.2e-118  394.2   0.3    1.0  1  Amidase          Amidase
  ------ inclusion threshold ------
      0.075   12.8   0.2        7.5    6.4   0.1    3.0  3  Eno-Rase_NADH_b  NAD(P)H binding domain of trans-2-enoyl-CoA 


Domain annotation for each model (and alignments):
>> Amidase  Amidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  394.2   0.3  9.1e-122  8.2e-118      33     451 .]      38     502 ..      12     502 .. 0.94

  Alignments for each domain:
  == domain 1  score: 394.2 bits;  conditional E-value: 9.1e-122
                 HT---TTT......TTTT-EEEEETTB--TTSB--TTSGGGTT-B-SS--HHHHHHHHTT-EEEEEE--SGGG-SSSSTT-TT---BB...TTCTCCB- CS
     Amidase  33 akldkkrargkekgpLhGvPisvKDnidvkgvpttaGskalenypaekDatvverLkkaGavilgkTnmdefamgsstensvfgptrN...Pwdksrtp 128
                 + +d +r++g++k+pL G  i++KDni+++ +ptt++s++le++ +++Datv++ L++aGa+i gkTn+def+mgs + +s fgp++N    +d s ++
  EEA19793.1  38 RDADIRRENGTSKSPLDGRLIAIKDNICTRSLPTTCASRMLEKFSSPFDATVIKSLENAGAIIGGKTNLDEFGMGSHSTHSHFGPVKNyfeTVDGSLSA 136
                 567788889*******************************************************************************444446678** PP

                 -SSSHHHHHHHHTTSSSCEEEEESSSTTHHHHHHCTSEEEE--TTSC--TTB--SSTTT-EEEEEESSHHHHHHHHHHHBS--TT-TTS----...... CS
     Amidase 129 GGSSGGsAAavAaglvplaiGtDtGGSiRiPAsfcglvGlKPtygrvSragvvalessldvvGplarsvedlalllrvilgedpkdstssvip...... 221
                 GGSSGGsA+avA +++ +a+GtDtGGS+R+PA+++g+vG+KP+yg++Sr+gv+a+++sld+vG+la++ +++  ++  +  +d +d+ts++        
  EEA19793.1 137 GGSSGGSAVAVATDQCYAALGTDTGGSVRLPAAYTGVVGFKPSYGLISRWGVIAYANSLDTVGILAKRTSTVHEVFNILNHHDGQDPTSLSTAtrsria 235
                 ******************************************************************************************988999999 PP

                 HHHHHHHHCTT---TT-EEEEEGGGCSS---CCHHHHHHHHHHHHHCTT-EEEEEE-CCGGGHHHHHHHHHHHHHHHHTTT-SSSSS.---SS-S.... CS
     Amidase 222 eesedlaeelkkslkglriGvvkedgvasldpevqravekalkaLeeaGhevvevelpsleealslyylilvaeassnlarylgvry.erlsetk.... 315
                  ++ +l +++  s+++lriGv+ e++ +++   v++a ++al++Le++Gh++ +++lps ++als+yy +++aeassnla+y+g+ry +r+++++    
  EEA19793.1 236 TAVSQLHSSSRLSSRPLRIGVPIEYNLTEMASTVREAWLSALRTLEQQGHTLHPISLPSTKHALSAYYVLAPAEASSNLAKYDGIRYgKRADGPDkgee 334
                 8888999999999***************************************************************************77776662222 PP

                 .CCCCCCCHHHHCCS-HHHHHHHHHHHHHCSCCCCCCCHHHHHHHHHHHHHHHHHHCCC....................BSEEEEESSSSS--BCCCCC CS
     Amidase 316 .vlsellpksraellgeevkrrielgnyalsaeasskyylkaqkvrrllrrefakafee....................lDvllsPtaptpaprlgekd 393
                  +++ l++++r e++g+ev+rri lg++ lsa+a ++y+ +aq+vrrl++++f+ +f                      +Dv++ Pt+++ +p+l   +
  EEA19793.1 335 gSKDYLYSRTRGEGFGDEVRRRILLGSFSLSADAMDNYFVQAQRVRRLVQNDFDHIFALknplgddaevenqasptetkVDVIIGPTTASLPPSLASVT 433
                 246789****************************************************99************************************999 PP

                 HHH....CSHHHHHGCCTTT...HHHHHTT--EEEEECCCCT...........TECEEEEEEESTT-HHHHH CS
     Amidase 394 kti....dsytvlynlldftavvvpvnlaglpalsvpagksed..........glPvGvqvigkafqeetlL 451
                 ++       ++ +y  +++t   vp++laglpa+svp+  + +             vG+q+ig+++++  +L
  EEA19793.1 434 EDQdaavSAPLHSYVTDVCT---VPASLAGLPAVSVPISVTSTgesqedgklaFNKVGIQIIGQYGDDDLVL 502
                 98888888899999999999...****************99888999999887557************9997 PP

>> Eno-Rase_NADH_b  NAD(P)H binding domain of trans-2-enoyl-CoA reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0     0.013   1.2e+02       6      37 ..      60      91 ..      58     120 .. 0.75
   2 ?    6.4   0.1   0.00083       7.5      45      77 ..     173     206 ..     165     208 .. 0.87
   3 ?   -1.5   0.0      0.24   2.2e+03      10      33 ..     390     413 ..     387     422 .. 0.76

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.013
                     EETTEESS--HHHHHHHHHHHHHHHHHS---- CS
  Eno-Rase_NADH_b  6 irgficltahPaGcaknveeqieyvksqkkie 37
                     i+++ic+ + P+ ca  + e+ +   +++ i+
       EEA19793.1 60 IKDNICTRSLPTTCASRMLEKFSSPFDATVIK 91
                     799************99988877655555555 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.00083
                      EESTSSHHHHHHHHH.HHHSS--EEEEEE----- CS
  Eno-Rase_NADH_b  45 viGaStGYGLAsria.aafgagadtigVsfekea 77 
                      v+G   +YGL sr   +a++   dt+g+   + +
       EEA19793.1 173 VVGFKPSYGLISRWGvIAYANSLDTVGILAKRTS 206
                      7888889******9768999********987765 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 0.24
                      EESS--HHHHHHHHHHHHHHHHHS CS
  Eno-Rase_NADH_b  10 icltahPaGcaknveeqieyvksq 33 
                      i+   +P G  ++ve+q + ++++
       EEA19793.1 390 IFALKNPLGDDAEVENQASPTETK 413
                      555678999999999998877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (516 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       400  (0.0223102); expected 358.6 (0.02)
Passed bias filter:                      349  (0.0194657); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.24s 00:00:00.75 Elapsed: 00:00:00.40
# Mc/sec: 3889.46
//
Query:       EEA19794.1  [L=655]
Description: histone-lysine N-methyltransferase (Bre2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (655 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       725  (0.0404373); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.45
# Mc/sec: 4379.89
//
Query:       EEA19795.1  [L=507]
Description: rRNA processing protein Bystin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.3e-131  437.4   0.0   3.6e-131  436.8   0.0    1.3  1  Bystin    Bystin


Domain annotation for each model (and alignments):
>> Bystin  Bystin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  436.8   0.0    2e-135  3.6e-131       4     290 ..     166     485 ..     163     487 .. 0.94

  Alignments for each domain:
  == domain 1  score: 436.8 bits;  conditional E-value: 2e-135
      Bystin   4 rktLadlilekieekeaekesklekee...eeeeeeeldpkvvevYekvgelLsrYksGklpkafkilpslknWeellaltePekWtpnavyeatrifv 99 
                   +Ladlil+ki++ ea+++ + ++ +   ++e+++++++k +evYekvg++LsrYksG+lpk+fkilp+l++W +ll +t+P++Wt+navy+ trif+
  EEA19795.1 166 GINLADLILQKIAAYEANQSGDGQQIKgggAPEDAVQIPAKALEVYEKVGMILSRYKSGPLPKPFKILPTLPQWPTLLDITRPDTWTANAVYAGTRIFI 264
                 579**************999776666667899******************************************************************* PP

      Bystin 100 snlkekkaqrflelvllprvrddieenkkLnvhlyeaLkkalykpaaffkgillPLvesgtctlreaaivgsvlakvsipvlhsaaallklael..... 193
                 s+ k++ aq+f+++vll+rvrd+i+e++kLnvh+y+aLkkalykpa+ffkg+l+PL+++gtctlrea+iv+sv+a+vsipvlhsaaall+l+e+     
  EEA19795.1 265 SS-KPAIAQQFINMVLLERVRDEIHETRKLNVHVYNALKKALYKPACFFKGLLFPLIATGTCTLREAHIVSSVIARVSIPVLHSAAALLRLCEIaaeqt 362
                 **.************************************************************************************************ PP

      Bystin 194 ......eysgatslfirvlldKkyaLpykvvdalvfhFlrfree...........kre..........lpvlwhqsllvfaqrYknditedqkeaLldl 265
                       e +gat++firv+l+KkyaLpykv+dalvfhFlrfr++           + +          lpvlwhqsllvfaqrY+nditedq+eaLldl
  EEA19795.1 363 saslssEGTGATNMFIRVFLEKKYALPYKVIDALVFHFLRFRAMdnnedsmmvdgN-RqsaaaamnykLPVLWHQSLLVFAQRYRNDITEDQREALLDL 460
                 ******************************************77444444444441.04555666666******************************* PP

      Bystin 266 lkkkkhkkitpeirrellasksrgv 290
                 l +++hk+i+pe+rrella+++rgv
  EEA19795.1 461 LLVRGHKEIGPEVRRELLAGRGRGV 485
                 **********************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (507 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       806  (0.0449551); expected 358.6 (0.02)
Passed bias filter:                      542  (0.0302304); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.43
# Mc/sec: 3581.25
//
Query:       EEA19796.1  [L=367]
Description: rRNA processing protein Bystin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.1e-131  438.5   0.0   1.2e-131  438.3   0.0    1.0  1  Bystin    Bystin


Domain annotation for each model (and alignments):
>> Bystin  Bystin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  438.3   0.0  6.9e-136  1.2e-131       4     290 ..      26     345 ..      23     347 .. 0.94

  Alignments for each domain:
  == domain 1  score: 438.3 bits;  conditional E-value: 6.9e-136
      Bystin   4 rktLadlilekieekeaekesklekee...eeeeeeeldpkvvevYekvgelLsrYksGklpkafkilpslknWeellaltePekWtpnavyeatrifv 99 
                   +Ladlil+ki++ ea+++ + ++ +   ++e+++++++k +evYekvg++LsrYksG+lpk+fkilp+l++W +ll +t+P++Wt+navy+ trif+
  EEA19796.1  26 GINLADLILQKIAAYEANQSGDGQQIKgggAPEDAVQIPAKALEVYEKVGMILSRYKSGPLPKPFKILPTLPQWPTLLDITRPDTWTANAVYAGTRIFI 124
                 579**************999776666667899******************************************************************* PP

      Bystin 100 snlkekkaqrflelvllprvrddieenkkLnvhlyeaLkkalykpaaffkgillPLvesgtctlreaaivgsvlakvsipvlhsaaallklael..... 193
                 s+ k++ aq+f+++vll+rvrd+i+e++kLnvh+y+aLkkalykpa+ffkg+l+PL+++gtctlrea+iv+sv+a+vsipvlhsaaall+l+e+     
  EEA19796.1 125 SS-KPAIAQQFINMVLLERVRDEIHETRKLNVHVYNALKKALYKPACFFKGLLFPLIATGTCTLREAHIVSSVIARVSIPVLHSAAALLRLCEIaaeqt 222
                 **.************************************************************************************************ PP

      Bystin 194 ......eysgatslfirvlldKkyaLpykvvdalvfhFlrfree...........kre..........lpvlwhqsllvfaqrYknditedqkeaLldl 265
                       e +gat++firv+l+KkyaLpykv+dalvfhFlrfr++           + +          lpvlwhqsllvfaqrY+nditedq+eaLldl
  EEA19796.1 223 saslssEGTGATNMFIRVFLEKKYALPYKVIDALVFHFLRFRAMdnnedsmmvdgN-RqsaaaamnykLPVLWHQSLLVFAQRYRNDITEDQREALLDL 320
                 ******************************************77444444444441.04555666666******************************* PP

      Bystin 266 lkkkkhkkitpeirrellasksrgv 290
                 l +++hk+i+pe+rrella+++rgv
  EEA19796.1 321 LLVRGHKEIGPEVRRELLAGRGRGV 345
                 **********************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (367 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       337  (0.0187964); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.40
# Mc/sec: 2755.78
//
Query:       EEA19797.1  [L=429]
Description: bZIP transcription factor HacA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.8e-11   42.1  16.2    6.8e-11   42.1  16.2    2.6  3  bZIP_2    Basic region leucine zipper
    2.9e-06   27.3  16.9    2.9e-06   27.3  16.9    1.9  2  bZIP_1    bZIP transcription factor
     0.0024   18.3  14.4     0.0024   18.3  14.4    1.9  2  bZIP_Maf  bZIP Maf transcription factor
  ------ inclusion threshold ------
        0.1   13.1  14.5       0.12   12.9  12.9    2.0  2  APG6_N    Apg6 coiled-coil region


Domain annotation for each model (and alignments):
>> bZIP_2  Basic region leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.1  16.2   1.5e-14   6.8e-11       2      54 .]      81     134 ..      77     134 .. 0.96
   2 !    5.8   1.0    0.0031        14      33      54 .]     127     148 ..     127     148 .. 0.91
   3 ?   -3.2   1.3       2.1   9.3e+03      15      27 ..     399     411 ..     391     415 .. 0.76

  Alignments for each domain:
  == domain 1  score: 42.1 bits;  conditional E-value: 1.5e-14
                 XXXXXXXXX.XXXXXXXX-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_2   2 ddeyrerRr.kNreAarrsRekkkakeeeleervkeLeeeNaqLrqkveqLeke 54 
                 ++++r +R  +Nr+Aa++sRe+k+++ e+le + +++e++N++L+q+++q+e+e
  EEA19797.1  81 KEQRRIERVlRNRAAAQTSRERKRLEVEKLEGEKQRMEQQNQFLLQRLAQMEAE 134
                 6788999*********************************************98 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0031
                 HHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_2  33 rvkeLeeeNaqLrqkveqLeke 54 
                 r+ ++e+eN++L  +v+qL +e
  EEA19797.1 127 RLAQMEAENNRLNLQVAQLSAE 148
                 6789***************887 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 2.1
                 XXXX-HHHHHHHH CS
      bZIP_2  15 AarrsRekkkake 27 
                 A +rs+  +k+++
  EEA19797.1 399 ALKRSKSQRKQMK 411
                 5588888888865 PP

>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3  16.9   6.5e-10   2.9e-06       1      62 [.      80     141 ..      80     143 .. 0.95
   2 ?   -4.2   1.5         4   1.8e+04      51      59 ..     402     410 ..     397     413 .. 0.45

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 6.5e-10
                 XXXXXXXXXX--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1   1 ekelKrekrkqkNReaArrsRqRKqaeieeLerrvkaLekeNksLkseleelkkevekLksk 62 
                 eke +r  r ++NR aA+ sR+RK+ e+e+Le + + +e++N+ L ++l +++ e++ L  +
  EEA19797.1  80 EKEQRRIERVLRNRAAAQTSRERKRLEVEKLEGEKQRMEQQNQFLLQRLAQMEAENNRLNLQ 141
                 7999*************************************************999988766 PP

  == domain 2  score: -4.2 bits;  conditional E-value: 4
                 HHHHHHHHH CS
      bZIP_1  51 elkkevekL 59 
                 + k +++++
  EEA19797.1 402 RSKSQRKQM 410
                 333333333 PP

>> bZIP_Maf  bZIP Maf transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3  14.4   5.4e-07    0.0024      22      91 ..      77     145 ..      67     146 .. 0.88
   2 ?   -3.0   0.5       2.4   1.1e+04      58      64 ..     402     408 ..     387     418 .. 0.46

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 5.4e-07
    bZIP_Maf  22 teeeverLKqrRRrlKNrgyakscrkrrlqqkeelekekeeleeelerlqqelsrlrqekdalkrkneql 91 
                 te+e  + +++ R l+Nr +a+++r+r+  + e+le ek+++e++++ l q+l+ +++e+++l  + +ql
  EEA19797.1  77 TEDEK-EQRRIERVLRNRAAAQTSRERKRLEVEKLEGEKQRMEQQNQFLLQRLAQMEAENNRLNLQVAQL 145
                 44444.44777799*************************************************9999887 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 2.4
    bZIP_Maf  58 kekeele 64 
                 ++k++ +
  EEA19797.1 402 RSKSQRK 408
                 2222111 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9  12.9   2.7e-05      0.12      21      91 ..      79     149 ..      72     153 .. 0.89
   2 ?   -3.0   0.0       2.3     1e+04      84      99 ..     397     412 ..     383     422 .. 0.51

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.7e-05
      APG6_N  21 aekerdaYeeflkklkkekkeeekqdeeleeleeeleklekeeeelleeLkelekereeleaelaaleeel 91 
                  eke +  e+ l++  + +++ e+++ e+e+le e +++e++ + ll+ L+++e+e+ +l+ ++a+l++e 
  EEA19797.1  79 DEKEQRRIERVLRNRAAAQTSRERKRLEVEKLEGEKQRMEQQNQFLLQRLAQMEAENNRLNLQVAQLSAEI 149
                 477788888888888888888777999*****************************************997 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 2.3
      APG6_N  84 laaleeelealeeeee 99 
                  +al++ ++++++ ++
  EEA19797.1 397 KRALKRSKSQRKQMKR 412
                 4444444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (429 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1423  (0.0793686); expected 358.6 (0.02)
Passed bias filter:                      483  (0.0269396); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.49
# Mc/sec: 2656.04
//
Query:       EEA19798.1  [L=215]
Description: SNF7 family protein Fti1/Did2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0014   18.3   9.1     0.0019   17.8   9.1    1.2  1  Snf7      Snf7
  ------ inclusion threshold ------
      0.016   15.5   1.4      0.016   15.5   1.4    2.4  2  DUF4157   Domain of unknown function (DUF4157)


Domain annotation for each model (and alignments):
>> Snf7  Snf7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   9.1   2.1e-07    0.0019       2     170 ..      10     175 ..       9     186 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 2.1e-07
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTT-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
        Snf7   2 airsLrkaerkldkkqeslekkikkleaelkklakkgnkdralllLKqkkryekqldqldnqlanleqvslaienlksnkevlnamkqgakamkamnkk 100
                 a+ +++ + ++l+k+  + e   k ++a++ k  k  + + a++ +   +r  k   +l++  a+ + +  +++ ++s+ ++ +++  + + + a++k 
  EEA19798.1  10 ARTNVKLHSNRLKKEALRAEATYKSEKAKADKAMKNREFQIARIHAGSAVREKKRQVNLKAEAARADVIINELKAAQSTRDTSRTLALASRGLDAASKS 108
                 5667778899********************99999999999999999999999999999999999999******************************* PP

                 TCCHHHHHHHHHHHHHHHHHTCHHHHHHHHHTT-.GGTTHHHHHHHHHHHHHHHHHCSH.HHHHHHHTXXX CS
        Snf7 101 vdidkidklmdeiedqmekaeeisEalsrsldda.deedEeeleaeLdaLeqelgdeelldesvklpevPs 170
                 v+++ +     ++   +e  ++ s+a+s+  + + ++e+ +e e e+d++ ++l+d+     +v+l ++ +
  EEA19798.1 109 VNLEHLLAHANNFLARSEDFKIASNAISDVAQGVsQQEYGAEGESEVDRMMEQLADDA----GVDLRNALD 175
                 *******************************998988888888888888888877777....444444443 PP

>> DUF4157  Domain of unknown function (DUF4157)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.5   1.4   1.7e-06     0.016       7      66 ..      36      96 ..      30      96 .. 0.88
   2 ?   -3.6   0.2       1.6   1.4e+04      61      67 ..     111     117 ..     104     117 .. 0.71

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1.7e-06
     DUF4157  7 raemerafgad.lsdVrvhtgsaaaraaralgAqAfTlgndivfaageyqpesaagrella 66
                +a++ +a+ +  ++ +r+h gsa ++  r+++ +A +   d+++++ + ++++++  ++la
  EEA19798.1 36 KAKADKAMKNReFQIARIHAGSAVREKKRQVNLKAEAARADVIINELKAAQSTRDTSRTLA 96
                567777888666*********************************9999999998888776 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 1.6
     DUF4157  61 grellaH 67 
                  ++llaH
  EEA19798.1 111 LEHLLAH 117
                 4789998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (215 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1043  (0.0581739); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.46
# Mc/sec: 1404.35
//
Query:       EEA19799.1  [L=465]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.3e-28   99.1  28.6      8e-15   54.6  10.4    2.1  2  MFS_1       Major Facilitator Superfamily
    3.4e-06   26.2  24.3    0.00037   19.5  24.3    3.2  1  Sugar_tr    Sugar (and other) transporter
    2.8e-05   22.8  24.3     0.0049   15.5   9.2    3.2  4  MFS_2       MFS/sugar transport protein
    6.1e-05   22.1  14.1      0.008   15.1   2.7    2.4  3  MFS_1_like  MFS_1 like family
     0.0052   16.4   0.1     0.0052   16.4   0.1    2.3  3  DUF1624     Protein of unknown function (DUF1624)
  ------ inclusion threshold ------
       0.28    9.9   8.1       0.36    9.6   0.3    2.6  3  LacY_symp   LacY proton/sugar symporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.7   9.9   4.1e-17   1.2e-13       6     187 ..      29     224 ..      24     253 .. 0.83
   2 !   54.6  10.4   2.7e-18     8e-15       2     183 ..     270     452 ..     269     462 .. 0.83

  Alignments for each domain:
  == domain 1  score: 50.7 bits;  conditional E-value: 4.1e-17
       MFS_1   6 flsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlga..... 99 
                 f+  +a++  +++l   + ++l is + igl +tl  +g ++ s++l  ++dr+Gr+ vlllg ++++ ++++++++ ++w+ll++ vl  +       
  EEA19799.1  29 FVRLFAYGGSTLILA-SYLSSLDISDDRIGLFMTLTLVGDVFISFFLTLFADRLGRKAVLLLGSAMMCGSGVAFALSGNYWVLLLAAVLGVISPggnei 126
                 788899999999999.666999************************************99999999999966666679999777777765554400024 PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg..........Wravfyilaivsllafvlfllllpeepperkrkspkee 187
                 g + ++  + ia++++ke+ +  ++++s+   +G++lg+++ g+++++l            r+vf++ a+v++  f+l + l    ++++k++  +  
  EEA19799.1 127 GPFRAVEESTIAHITAKEHMSDIYAWYSLIGTAGTALGMMVCGWVMTLLQetkqwdfvpaCRVVFIMYAGVGATKFLLTMGLSKSVEVQKKKEDNAAT 224
                 6688889999***********************************************9999*************999666655555555555544444 PP

  == domain 2  score: 54.6 bits;  conditional E-value: 2.7e-18
       MFS_1   2 llaaflsalarsilgpalpl.alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlga 99 
                 ll++ l ++++s+++++    +  + +g+s  e+g l+++ ++ +a+++l++++++ rfG  r+++++ l ++++l+ +++ +++ +l+   ++  +++
  EEA19799.1 270 LLLFGLDSFGSSLASLSWITyYFRRKFGMSDGELGSLFSITSVIQAISMLLASSIAKRFGNVRTMVFTHLPSCIFLATMSL-PNSLPLAMTLLIGRACT 367
                 678889999999999999999******************************************************333335.77776777777777777 PP

       MFS_1 100 .galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivslla..fvlfllllpeepperkrks 183
                   + ++   a++a+  p ++r+  +g +++    ++ l+pll g+l+ss+    +f+i++ + +    ++l  + + + ++e++rk+
  EEA19799.1 368 qNMDVAPRSAFLAEALPADQRTAIMGTINVVKTTASSLAPLLTGILSSSGKLWISFVIAGCMKIAYdlGIL--ATFGAMDREHRRKA 452
                 5888999****************************************887755779999988888766556..44444444444443 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5  24.3   1.2e-07   0.00037      44     428 ..      52     431 ..      34     442 .. 0.72

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 1.2e-07
                 ...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHH.....HHHHHHHTTS-SCCHH CS
    Sugar_tr  44 ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasv.....lvPmyisEiApkklRg 137
                 s+ ++gl++ ++lvG ++ s+f+ l++dr+GRk +ll ++++++ ++v  a++    +++vl+++ vl  i+ G+  +     +   +i+ i+ k++ +
  EEA19799.1  52 SDDRIGLFMTLTLVGDVFISFFLTLFADRLGRKAVLLLGSAMMCGSGVAFALSG---NYWVLLLAAVLGVISPGGNEIgpfraVEESTIAHITAKEHMS 147
                 56689*************************************************...9*******9998777766654111115566777777999999 PP

                 HHHHHHHHHHHHHHHHHHHH.HHHHHTSS-TTHHHHHHHCCHHH....HHHHHHHGGGS---HHHHHHTT-HHHHHHHHHHHHHCHHHHHHHHHHHHHH CS
    Sugar_tr 138 alvslyqlaitfGilvaaif.glglnktsnadgwrillglqlvp....allllilllflPESPrylvekgkeeeakevlaklrgeedadrelaeekdsl 231
                  +  +y l  t+G  ++ ++ g+++   +++++w +  +  +v+     +    +ll++  S+   v+k+ke+ a +  ++  ++++   + +e  +s 
  EEA19799.1 148 DIYAWYSLIGTAGTALGMMVcGWVMTLLQETKQWDFVPACRVVFimyaGVGATKFLLTMGLSKSVEVQKKKEDNAATAPSE--TDPLLGSNGQETEESV 244
                 9999*****999999998752677788888999988887777661111222233445555555555555555555555555..3333333333333332 PP

                 HHHHH.........HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH...HHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHH CS
    Sugar_tr 232 eaeqeee....kaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsks...llvtiivgvvnfvatfvaiflvdrfGRRtllllG 323
                    ++++         el++ +t    ll+ ++l++f      +++  +  ++ ++ g+s+     l+  i++v+++++ + a  + +rfG  ++++  
  EEA19799.1 245 VPPKQKKlfflPGVEAELVGLVT---SLLLLFGLDSFGSS--LASLSWITYYFRRKFGMSDGelgSLF-SITSVIQAISMLLASSIAKRFGNVRTMV-- 335
                 22222222223333333333333...56666666555444..4567777778**********543333.3678888888888888999999866555.. PP

                 HHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHH CS
    Sugar_tr 324 aagmaicfvilgivalllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvf 422
                  ++ +  +++l+  ++ l+++      +a+++++  ++  ++ ++p  ++l +E  p + R++ +    +v+ +a+ l  ll+ i+ ++ +  ++ +v 
  EEA19799.1 336 -FTHLPSCIFLA--TMSLPNS----LPLAMTLLIGRACTQNMDVAPRSAFL-AEALPADQRTAIMGTINVVKTTASSLAPLLTGILSSSGK-LWISFVI 425
                 .45556666776..6678888....79*********************888.9*********************************99999.9999999 PP

                 HHHHHH CS
    Sugar_tr 423 aglavl 428
                 ag++ +
  EEA19799.1 426 AGCMKI 431
                 999866 PP

>> MFS_2  MFS/sugar transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   9.2   1.7e-06    0.0049     254     383 ..      48     174 ..      21     181 .. 0.77
   2 !    5.2   1.1    0.0021       6.3     302     347 ..     160     216 ..     138     225 .. 0.63
   3 !   14.5   3.1   3.2e-06    0.0097     234     333 ..     275     372 ..     261     413 .. 0.76
   4 ?   -0.9   0.1      0.15   4.5e+02     107     180 ..     363     429 ..     354     460 .. 0.55

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1.7e-06
       MFS_2 254 vlg.ngsaasvfllvvtisallgiplwqplakrlgkkntyllgalltivllvlvlllqpsnlllflvllviagfgvgvaallpwsmladvvDygelktG 351
                  l+ +++ + +f++++ ++ +  +++   +a rlg+k++ llg++ ++ ++ ++++l  +n++++l+++v++ ++ g+  + p      +v++++    
  EEA19799.1  48 SLDiSDDRIGLFMTLTLVGDVFISFFLTLFADRLGRKAVLLLGSA-MMCGSGVAFAL-SGNYWVLLLAAVLGVISPGGNEIGPF----RAVEESTIAHI 140
                 45558899999*************************998888876.56788888889.9*****99999999999776666665....45555555544 PP

       MFS_2 352 krregv..ffavlsfisklatgiglgvsgllLsa 383
                 + +e++  ++a +s+i  ++t++g++v g++ ++
  EEA19799.1 141 TAKEHMsdIYAWYSLIGTAGTALGMMVCGWVMTL 174
                 55555555**********************9886 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0021
       MFS_2 302 llvlvlll...........qpsnlllflvllviagfgvgvaallpwsmladvvDyge 347
                 +++l +++           ++++ ++++ +++i + gvg+  +l+++ l+ +v++  
  EEA19799.1 160 GTALGMMVcgwvmtllqetKQWDFVPACRVVFIMYAGVGATKFLLTMGLSKSVEVQK 216
                 333333333333334445578888888888888888888888888887777777665 PP

  == domain 3  score: 14.5 bits;  conditional E-value: 3.2e-06
       MFS_2 234 llaalalgvlnglllYyltyvlg.ngsaasvfllvvtisallgiplwqplakrlgkkntyllgalltivllvlvlllqpsnlllflvllviagfgvgva 331
                 l  + + +   ++  Yy++   g ++ +   ++ ++ + ++++++l++ +akr+g+ +t+++  l   ++l+ + l    n l++ + l+i+  +++ +
  EEA19799.1 275 LDSFGSSLASLSWITYYFRRKFGmSDGELGSLFSITSVIQAISMLLASSIAKRFGNVRTMVFTHLPSCIFLATMSLP---NSLPLAMTLLIGRACTQNM 370
                 333444466789999****9999977777777777888888****************99999999999888888776...5555555555555555555 PP

       MFS_2 332 al 333
                  +
  EEA19799.1 371 DV 372
                 55 PP

  == domain 4  score: -0.9 bits;  conditional E-value: 0.15
       MFS_2 107 lrilytlfeipyvslvpvltkdydeRtsltsvrsflsvlggvlaailafllvlilgglkserkgylifaliial 180
                  r ++  ++++  s   + +   d+Rt +++  +++++ ++ la +l+++l    ++   + k ++ f++ +++
  EEA19799.1 363 GRACTQNMDVAPRSAFLAEALPADQRTAIMGTINVVKTTASSLAPLLTGIL----SS---SGKLWISFVIAGCM 429
                 555555566655555555556667777777777777776666666666555....33...34555555555554 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.0   6.7   1.1e-05     0.033     239     373 ..      33     171 ..      20     173 .. 0.85
   2 !   15.1   2.7   2.7e-06     0.008     136     310 ..     136     351 ..     128     367 .. 0.72
   3 !   10.0   1.0   9.5e-05      0.28      19      86 ..     285     351 ..     267     429 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 1.1e-05
  MFS_1_like 239 mswgiienFlflYLkelgasntllGslvalgvvaeiplfffaeklleklGhvklliiallayilrfllyaiienawlvlpievLhgis.....fgllwa 332
                 +++g     l  YL++l+ s   +G +++l+ v+ + + ff     ++lG   +l+++  ++    +  a+  n w++l++ vL  is     +g + a
  EEA19799.1  33 FAYGGSTLILASYLSSLDISDDRIGLFMTLTLVGDVFISFFLTLFADRLGRKAVLLLGSAMMCGSGVAFALSGNYWVLLLAAVLGVISpggneIGPFRA 131
                 455555555899***************************************************999999999************988833333456677 PP

  MFS_1_like 333 aaveyvskiapksleatgqgllsglyfglGralGsliGGll 373
                 +  + +++i+ k++ + + + +s +   +G+alG +++G +
  EEA19799.1 132 VEESTIAHITAKEHMSDIYAWYSLI-GTAGTALGMMVCGWV 171
                 7778999999999999999999988.57899***9999976 PP

  == domain 2  score: 15.1 bits;  conditional E-value: 2.7e-06
  MFS_1_like 136 tlkel..gedrkd.yGrqrlfGsvGyaifafitGilidhysvnllp......ysallyvlaallvisllvvlilnetekesklkvtksl.......... 215
                 t+ ++  +e+  d y+   l G+ G a+ +++ G++++ ++ +  +      ++++++++a++  + +l+ + l +    +k k  +            
  EEA19799.1 136 TIAHItaKEHMSDiYAWYSLIGTAGTALGMMVCGWVMTLLQETK-QwdfvpaCRVVFIMYAGVGATKFLLTMGLSKSVEVQKKKEDNAAtapsetdpll 233
                 55555444444556888888899999999999999998877643.235666*999*******9999999877666554444444443335679****** PP

  MFS_1_like 216 .................qvllnilknpeviifllvalilgmswgiienF.....lflYL.kelgasntllGslvalgvvaeiplfffaeklleklGhvk 291
                                  + ++    + e++++++ +l+l  + ++  +      ++ Y+  + g s   lGsl  ++ v + +  ++a+ + +++G v+
  EEA19799.1 234 gsngqeteesvvppkqkKLFFLPGVEAELVGLVTSLLLLFGLDSFGSSLaslswITYYFrRKFGMSDGELGSLFSITSVIQAISMLLASSIAKRFGNVR 332
                 *****999999997754222222345566666666666554444433335555488888899***********************************99 PP

  MFS_1_like 292 lliiallayilrfllyaii 310
                  +++++l   + +  +++ 
  EEA19799.1 333 TMVFTHLPSCIFLATMSLP 351
                 9999998877777766665 PP

  == domain 3  score: 10.0 bits;  conditional E-value: 9.5e-05
  MFS_1_like  19 lPYltiylk.skglkaseigiitlilpltsilsppiwgvlaDrfgkrkkvvilslllsavlflsllfip 86 
                 l ++t y++ + g++  e g + +i  +++ +s ++ + +a rfg   ++v ++ l s+++++ +  +p
  EEA19799.1 285 LSWITYYFRrKFGMSDGELGSLFSITSVIQAISMLLASSIAKRFGNVRTMV-FTHLPSCIFLATMS-LP 351
                 347889998567999999999999999999999999999999999988866.44555666655444.44 PP

>> DUF1624  Protein of unknown function (DUF1624)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.8       1.6   4.8e+03     102     135 ..      59      95 ..      25     119 .. 0.53
   2 !   16.4   0.1   1.7e-06    0.0052      10      70 ..     160     220 ..     158     226 .. 0.93
   3 ?   -1.4   0.2      0.47   1.4e+03      84     136 ..     310     363 ..     282     391 .. 0.56

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 1.6
     DUF1624 102 FGiLhlia...lalllallflrlpkalllllallila 135
                 F  L l++   ++  l+l+  rl+++++lll+ +++ 
  EEA19799.1  59 FMTLTLVGdvfISFFLTLFADRLGRKAVLLLGSAMMC 95 
                 4444444433355555555555555555555544444 PP

  == domain 2  score: 16.4 bits;  conditional E-value: 1.7e-06
     DUF1624  10 GiAlilMiifHflfdLeffgylavslatsglwvvfarliaslFlfiaGvslvlahskslrw 70 
                 G Al +M+   +++ L++ + ++   a   ++ ++a++ a+ Fl+ +G+s ++ ++k+++ 
  EEA19799.1 160 GTALGMMVCGWVMTLLQETKQWDFVPACRVVFIMYAGVGATKFLLTMGLSKSVEVQKKKED 220
                 89**********************99999*************************9998765 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.47
     DUF1624  84 allitaatylllpdsfivFGiLhlialalllallf.lrlpkalllllallilal 136
                   +i+a+++ll  +    FG    +    l   +f ++++  + l la+ +l++
  EEA19799.1 310 TSVIQAISMLLASSIAKRFGNVRTMVFTHLPSCIFlATMSLPNSLPLAMTLLIG 363
                 444444444433333334444444443333333332333333444433444333 PP

>> LacY_symp  LacY proton/sugar symporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.3   0.00012      0.36     248     321 ..      43     116 ..      38     121 .. 0.85
   2 ?   -2.4   0.1      0.52   1.5e+03     143     182 ..     153     193 ..     130     201 .. 0.75
   3 ?    4.2   0.5    0.0049        15      28      79 ..     286     337 ..     269     363 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00012
   LacY_symp 248 kslfespeaGtrvfGyvttagellnalimfiaplivnriGaknalliagvimsvrilgsafattalevvilkll 321
                 +s+++s +      G   t   + +  i f+  l+ +r+G k  ll+++++m+   ++ a++ + + + +  +l
  EEA19799.1  43 ASYLSSLDISDDRIGLFMTLTLVGDVFISFFLTLFADRLGRKAVLLLGSAMMCGSGVAFALSGNYWVLLLAAVL 116
                 5677777777777899999999999***************************9999999999998888877666 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.52
   LacY_symp 143 arvfGclGyalcaslaGilfsidpslvfw.lasgfalilll 182
                   ++G+ G al+ +++G ++++ ++ + w ++  + +++++
  EEA19799.1 153 YSLIGTAGTALGMMVCGWVMTLLQETKQWdFVPACRVVFIM 193
                 55678899999999999888888777777566677777766 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.0049
   LacY_symp  28 plfpvwlkevlglsktetGivfsvislfsilfqplfGlisdklGlkkellwv 79 
                 ++++ +++ + g+s++e+G +fs+ s++  + + l   i  ++G  + ++++
  EEA19799.1 286 SWITYYFRRKFGMSDGELGSLFSITSVIQAISMLLASSIAKRFGNVRTMVFT 337
                 455667788899***************9999999999999999988887776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (465 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       613  (0.0341904); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.62u 0.28s 00:00:00.90 Elapsed: 00:00:00.46
# Mc/sec: 3056.47
//
Query:       EEA19800.1  [L=521]
Description: Fasciclin domain family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.2e-45  153.5   1.9    3.6e-25   88.7   0.1    2.2  2  Fasciclin  Fasciclin domain


Domain annotation for each model (and alignments):
>> Fasciclin  Fasciclin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.3   0.3   6.6e-22   1.2e-17       4     128 .]     201     327 ..     198     327 .. 0.84
   2 !   88.7   0.1     2e-29   3.6e-25       2     128 .]     341     488 ..     340     488 .. 0.86

  Alignments for each domain:
  == domain 1  score: 64.3 bits;  conditional E-value: 6.6e-22
                 HHHHHHHHTT.TCCCCCTCSSSSEEEEEE-HHHHCCCHHHHHHHHHTCHHHHHHHHHTTEEESSS-HHHHHHHHEEEEC.CTTSS.....EEEEEEEGG CS
   Fasciclin   4 stfvslleka.glaeeLnkkdgglTvFaPtneAfaklppellakllndkkklkeiLkyHvvpetvsssalkkasetlat.llega.....klrvniekg 95 
                   f +++++  +++e Ln++  ++T+F+P ++Af+ +  ++ +    +k+     L+yH+ pe ++  ++ +  +t++t + e +     + r++++ +
  EEA19800.1 201 RIFTRIINQYdEVVEYLNSTSANYTIFVPIDAAFKGIHDKHHNI---SKETILHWLEYHISPEVFTFHDFFNV-QTVPTlSHE-KtkgkfPQRISTSLT 294
                 57889999987899****9999************8884444443...89***********************9.*****4333.358878445555444 PP

                 TTEEEETTEEEEEEEEEEESSEEEEEESS-TSX CS
   Fasciclin  96 ngtvtvngkarvvrsdieatngvihvidkvLlp 128
                 ++ +t+n  ++v+rsdi atng+ih +dk+++p
  EEA19800.1 295 RKGLTLNFYSHVIRSDIYATNGIIHAVDKLIIP 327
                 8889999999*********************98 PP

  == domain 2  score: 88.7 bits;  conditional E-value: 2e-29
                 GGHHHHHHHHTTTCCCCCT.CSSS...SEEEEEE-HHHHCCCHHHHHHHHHT..CHHHHHHHHHTTEEES.SS-HHHHHHH......HEE......... CS
   Fasciclin   2 dlstfvsllekaglaeeLn.kkdg...glTvFaPtneAfaklppellaklln..dkkklkeiLkyHvvpe.tvsssalkka......set......... 78 
                  +st+  +l k+gl ++L+ +      + T+FaPtn+Afaklp++ +a+l++  ++k+lk++LkyHvvp+  v ++a ++a      + +         
  EEA19800.1 341 LFSTLDLALVKTGLIDKLDpS--TlkiSGTIFAPTNQAFAKLPAKVNAFLFSpvGQKYLKALLKYHVVPGhIVFTDAHYNAksddgeE-Stliskkqfd 436
                 69****************652..345699*****************************************555788888875666550.0556666677 PP

                 EECCTTSSEEEEEEE..GGTTEEEETTEEEEEEEEEEESSEEEEEESS-TSX CS
   Fasciclin  79 latllegaklrvnie..kgngtvtvngkarvvrsdieatngvihvidkvLlp 128
                 l+t l+++++ ++i+  +  + +tvn+ a v  ++++   gvih ++++L+p
  EEA19800.1 437 LPTYLNKKPIAIDIRnfHRLTLMTVNNHAPVSVPNVPVREGVIHLVSSILIP 488
                 ***************776667999999***********************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (521 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       670  (0.0373696); expected 358.6 (0.02)
Passed bias filter:                      525  (0.0292822); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.27s 00:00:00.88 Elapsed: 00:00:00.45
# Mc/sec: 3474.36
//
Query:       EEA19801.1  [L=328]
Description: C2H2 finger domain protein (Kin17), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.7e-51  171.5   4.5    6.7e-51  171.5   4.5    1.8  2  Kin17_mid    Domain of Kin17 curved DNA-binding protein
  ------ inclusion threshold ------
      0.011   16.1   3.6      0.021   15.2   3.6    1.5  1  zf-met       Zinc-finger of C2H2 type
      0.013   15.8   2.7       0.03   14.6   2.7    1.7  1  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
      0.087   13.2   0.4      0.087   13.2   0.4    2.4  3  zf-C2H2_2    C2H2 type zinc-finger (2 copies)


Domain annotation for each model (and alignments):
>> Kin17_mid  Domain of Kin17 curved DNA-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  171.5   4.5   1.5e-54   6.7e-51       1     126 []      52     177 ..      52     177 .. 0.99
   2 ?   -2.0   0.5      0.71   3.2e+03      96     116 ..     289     309 ..     281     314 .. 0.54

  Alignments for each domain:
  == domain 1  score: 171.5 bits;  conditional E-value: 1.5e-54
   Kin17_mid   1 rqleliaentkkvieeyskeFekdFlklLrtrhgekkveankvYqeyiqdkdHvhmNaTkwtsLteFvkyLgkegkvkveetekgllisyidrspeale 99 
                 rq++li+en+k+ i++ys eF+++F++lLrt+hgekkv++n++Yq++i++k+H+hmNaTkwtsLt+F  yLg+eg+ +veetekgl+is+id+ pe+l+
  EEA19801.1  52 RQMLLIGENSKAAIDKYSAEFQREFIELLRTTHGEKKVHVNHFYQQVISNKSHIHMNATKWTSLTQFAAYLGREGIARVEETEKGLFISWIDNRPETLK 150
                 89************************************************************************************************* PP

   Kin17_mid 100 rkeklekkekaekedeereekllekqi 126
                 r+e+  kke+++k deere+kl+++q+
  EEA19801.1 151 RREAVMKKERQDKGDEEREQKLIQQQV 177
                 *************************97 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.71
   Kin17_mid  96 ealerkeklekkekaekedee 116
                 ++++++e + k+e + +e+++
  EEA19801.1 289 QKVSQQEMIMKREMEAMEQKK 309
                 445555555555554444444 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   3.6   4.7e-06     0.021       1      25 []      26      50 ..      26      50 .. 0.95

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 4.7e-06
      zf-met  1 fyCelCnvtfnsesqlksHlqGKkH 25
                +yC  C + + +e+ +k+H q+  H
  EEA19801.1 26 WYCQPCEKACRDENGFKCHVQSESH 50
                9********************9777 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   2.7   6.6e-06      0.03       2      26 ..      26      50 ..      25      51 .. 0.96

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 6.6e-06
                 CBBTTTTBBBSSHHHHHCCTTSHHH CS
  zf-C2H2_jaz  2 fYCvlCdKyFksenaldnHlkSKkH 26
                 +YC+ C+K + +en ++ H+ S +H
   EEA19801.1 26 WYCQPCEKACRDENGFKCHVQSESH 50
                 8*********************999 PP

>> zf-C2H2_2  C2H2 type zinc-finger (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.4   1.9e-05     0.087      43      92 ..      12      68 ..       5      75 .. 0.75
   2 ?   -0.9   0.2      0.47   2.1e+03      67      92 ..      96     118 ..      80     124 .. 0.62
   3 ?   -2.7   0.0       1.7   7.6e+03      26      48 ..     284     306 ..     276     311 .. 0.68

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.9e-05
   zf-C2H2_2 43 lrekiee......kleClyCekefkslealreHmkkkgHckine.eeeeekkeiekf 92
                +++ki++      ++ C  Cek +++ + ++ H+++++H + +    e++k++i+k+
  EEA19801.1 12 ISNKIKSkgltrlRWYCQPCEKACRDENGFKCHVQSESHVRQMLlIGENSKAAIDKY 68
                5566666666666899***********************997764344455666655 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.47
   zf-C2H2_2  67 reHmkkkgHckineeeeeekkeiekf 92 
                 ++ +++k+H  +n +   +++ + +f
  EEA19801.1  96 QQVISNKSHIHMNAT---KWTSLTQF 118
                 445567777777653...45555555 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 1.7
   zf-C2H2_2  26 fipereylvdleglleylrekie 48 
                 f+p+++++ ++e +++   e +e
  EEA19801.1 284 FVPQQQKVSQQEMIMKREMEAME 306
                 67777777777777666555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (328 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2017  (0.112499); expected 358.6 (0.02)
Passed bias filter:                      543  (0.0302861); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.49
# Mc/sec: 2028.18
//
Query:       EEA19802.1  [L=680]
Description: chromatin remodeling complex subunit (Arp9), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.2e-23   80.7   0.0    3.6e-20   72.0   0.0    2.9  3  Actin     Actin


Domain annotation for each model (and alignments):
>> Actin  Actin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.0   0.0     2e-24   3.6e-20      62     193 ..     143     274 ..      90     299 .. 0.79
   2 !    4.1   0.0   0.00079        14     306     351 ..     449     495 ..     385     513 .. 0.87
   3 ?    0.4   0.0     0.011   1.9e+02     389     404 ..     661     676 ..     636     678 .. 0.87

  Alignments for each domain:
  == domain 1  score: 72.0 bits;  conditional E-value: 2e-24
       Actin  62 rspvedGvvedwdaveelwehvlkeelkvdpeehpllltepplnppkqrekalEivfEkfkvpalylaksavlsafasgkstglvvDsGasvtsvvpVl 160
                  +p+++G+++dw  + +l+ehv+   l+   ++  l+++ep++ ++ +re +++ vfEkfk pa++l++sa  + +a+g  t+ vvD+G++++ v++Vl
  EEA19802.1 143 IYPIQNGHIVDWPCFLALLEHVYNT-LSPPFHTPILIISEPAW-SARDREILTQFVFEKFKPPAFCLMDSALAACYAYGTITATVVDVGYGKANVTAVL 239
                 58*******************9976.66555555555666666.5678*************************************************** PP

       Actin 161 dGyvLk..kairrsdlgGkaLteqlkellssknve 193
                 +  v +  ++i+    gG+++t+ l+ell  k ++
  EEA19802.1 240 EAAVQEngRGIALEGCGGETMTDRLEELLAPKGFT 274
                 *9987633689999**************9987544 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.00079
       Actin 306 selivaainacdvdl.rpeLlanivvtGGnsllpglteRlekelaql 351
                 +  i+++i a++    r++L  n +v G+ s ++g+   l + ++q+
  EEA19802.1 449 AAQIHHTILAVPDATkRSDLWDNLIVIGNGSRIRGFVPALLSTITQK 495
                 566888999997666599******************98887777775 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.011
       Actin 389 vskqEYeEqGssvver 404
                 + ++EY+E+G+s+++ 
  EEA19802.1 661 LPRSEYNENGPSAIHE 676
                 5699*********996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (680 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1065  (0.059401); expected 358.6 (0.02)
Passed bias filter:                      648  (0.0361426); expected 358.6 (0.02)
Passed Vit filter:                        86  (0.0047967); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.83u 0.28s 00:00:01.10 Elapsed: 00:00:00.48
# Mc/sec: 4298.58
//
Query:       EEA19803.1  [L=462]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      2e-38  132.3  29.1      2e-38  132.3  29.1    1.4  1  MFS_1          Major Facilitator Superfamily
  ------ inclusion threshold ------
       0.12   12.5   0.0       0.37   10.9   0.0    1.9  1  Epiglycanin_C  Mucin, catalytic, TM and cytoplasmic tail regi
          4    7.2   5.8         20    5.0   0.2    3.3  2  FixS           Cytochrome oxidase maturation protein cbb3-typ


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.3  29.1   3.3e-42     2e-38       5     339 ..      49     404 ..      45     418 .. 0.77

  Alignments for each domain:
  == domain 1  score: 132.3 bits;  conditional E-value: 3.3e-42
       MFS_1   5 aflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlgagal 102
                 +++++++++  ++a p  +a+dl  +p  +++  +++ +++++++l++++ls+ fGr++++ ++++++++   +++++++   ++ ++r++ Gl++  +
  EEA19803.1  49 TLIVTFSSTSMLIATP-EIATDLSTTPEILNITNAGVLVAMGLSALIWSPLSNLFGRKKIYNVAIFFMFVP-SIGAVVAPDLaTFTAMRLMGGLTGTYF 145
                 4555555555555555.9*****************************************************.66663455555**************** PP

       MFS_1 103 fpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllll..peepperkrkspkeee....kgtgpap 195
                 + ag+++i+d+f +  rg+a+g++++g+ +G++lgp +ggl+++   Wr ++++  ++s +++vl l+++  + +++e   +++ke++    + ++  p
  EEA19803.1 146 MVAGQTIITDIFEPLSRGQATGFFMVGSVAGPALGPCIGGLIVTFSHWRNIYWLQVAMSGFGLVLSLIVIpsVKREVEVIQVNGKEKLsffdALQKFNP 244
                 **************************************************************8874444444444444444444444466655555555 PP

       MFS_1 196 lvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrlsdr.............lgrrrrlllal 281
                 l   +++ll+++ l++ +++ +l++   +g+l+ +   ++ +++l++ l++gl++ +++++++++++++grl+dr             l+  r +   +
  EEA19803.1 245 LGV-FRQLLRPNILLADVTCGCLAA-TQYGILASVRHVINPRFNLTTPLISGLFYIAPGMGFFVGSIVGGRLADRtvkryiakrngirLPGDRLNSGLI 341
                 555.********5552233333332.4444666666678*******66***************************877777777777655588888888 PP

       MFS_1 282 lllllaalglallavt.....ssavllllvlvliGfglgfvfpsllalasdlappeeagtasg 339
                 +l++++ ++l+l+++         +l +++ v +G+gl  +f +l+++++++ p++ a  + +
  EEA19803.1 342 GLFVILPISLLLFGWGlqesiGGLALPIVAAVWAGVGLMGTFNALNTYTAEVNPAKTAEVICS 404
                 888888888888888874322333333335555999999999999999999988766665554 PP

>> Epiglycanin_C  Mucin, catalytic, TM and cytoplasmic tail region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   6.2e-05      0.37      17      61 ..      75     119 ..      63     166 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 6.2e-05
  Epiglycanin_C  17 eiiLitLvavvvavGllvgLsfCvrnllslrnladtavyrPhghn 61 
                    ei+ it + v+va+Gl++ +   + nl+ ++++ ++a++    ++
     EEA19803.1  75 EILNITNAGVLVAMGLSALIWSPLSNLFGRKKIYNVAIFFMFVPS 119
                    8999**********************************9887777 PP

>> FixS  Cytochrome oxidase maturation protein cbb3-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.2    0.0034        20      10      24 ..      82      96 ..      76     100 .. 0.86
   2 ?    2.7   1.2     0.018     1e+02       3      18 ..     343     358 ..     342     359 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0034
        FixS 10 SlllgllalaaFlWa 24
                + +l++++l a++W+
  EEA19803.1 82 AGVLVAMGLSALIWS 96
                779***********8 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.018
        FixS   3 LylLiplSlllgllal 18 
                 L++ +p+Slll + +l
  EEA19803.1 343 LFVILPISLLLFGWGL 358
                 899********98775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (462 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       497  (0.0277205); expected 358.6 (0.02)
Passed bias filter:                      248  (0.0138323); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.22s 00:00:00.75 Elapsed: 00:00:00.41
# Mc/sec: 3419.16
//
Query:       EEA19804.1  [L=245]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.8e-33  116.2   1.2    2.3e-33  115.8   1.2    1.2  1  DUF3328   Domain of unknown function (DUF3328)


Domain annotation for each model (and alignments):
>> DUF3328  Domain of unknown function (DUF3328)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.8   1.2   1.3e-37   2.3e-33       3     220 .]      28     230 ..      15     230 .. 0.75

  Alignments for each domain:
  == domain 1  score: 115.8 bits;  conditional E-value: 1.3e-37
     DUF3328   3 prkrssawrrl..lllvlllllllllllilssllsssekkaakkkspsspspaldaieyelkqfklgskeapsiyrgepsp.evdaaWddllkleaili 98 
                 p++ s +w  +  +l ++l +++ +++lils ++   + k        sp p+ +   y+ ++ +  ++ ++si+ +        ++W +l+ ++   +
  EEA19804.1  28 PETDSANWTHYkhHLRLFLEIFMAVVILILSIRSIYDKDKD---MNGRSPVPIFPLKTYTFNENS--KYMNESIFSSSDATlKTLHNWIELSAVGRGYV 121
                 66777778777552222222222333333332222222222...34679**********999988..999****9988877688****55555555555 PP

     DUF3328  99 preelrrlgkdpaaelevedkseggyiaglevfHqLHCLnllrkalypeyygypglsegeeeedrvHleHCidiLrqsimChaDvtlitfnwvkgtkgp 197
                   e+  ++g ++    ++e  +  + +++++vfHqLHCL+ l +a+++ +      + + ++e+ +H +HC+d+LrqsimC aD+tl++      +++ 
  EEA19804.1 122 QIEQDDAIGLSE--PYSIEAHWTTEPVYMMSVFHQLHCLSYLVQAYQSAFA-----GTALTQELAHHSSHCFDYLRQSIMCAADTTLEG------KTES 207
                 555544444444..3366667777**********************99999.....777777789***********************4......4899 PP

     DUF3328 198 vpdfntehqCrdfealldWaeen 220
                  p+++ +hqC+d++all+Wa+e+
  EEA19804.1 208 GPGWGSTHQCKDYDALLKWANEH 230
                 9********************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (245 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       530  (0.029561); expected 358.6 (0.02)
Passed bias filter:                      424  (0.0236488); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.31s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1601.20
//
Query:       EEA19805.1  [L=603]
Description: hexokinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.2e-49  168.1   0.0    3.1e-49  167.6   0.0    1.2  1  Hexokinase_1  Hexokinase
    7.6e-39  133.6   0.0      5e-38  130.9   0.0    2.0  1  Hexokinase_2  Hexokinase


Domain annotation for each model (and alignments):
>> Hexokinase_1  Hexokinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  167.6   0.0   3.4e-53   3.1e-49       2     199 .]      10     256 ..       9     256 .. 0.90

  Alignments for each domain:
  == domain 1  score: 167.6 bits;  conditional E-value: 3.4e-53
                   HHHHHHHH---HHHHHHHHHHHHHHHHHHHS.S....STS--EE----S---S--EEEEEEEEESSSEEEEEEEEEESSS................. CS
  Hexokinase_1   2 leeilkqfelsdeklkelvdrfleemekgLakek...eslkmlptyvtrlPtGkekGtylAlDlGgtnlRvllveLlges................. 78 
                   l+++l+++++sd++l++++++f ++++++La ++   ++ ++ p +vtrlP Gke+G+ylA+D+G t+l+v+++eLlge+                 
    EEA19805.1  10 LRDFLSPLQTSDAQLYDVACSF-SHVFRDLAANNgdiDDESFSPVPVTRLPVGKEHGRYLAVDVGITTLKVAFIELLGEDenkgypytrprsmsnmi 105
                   5799******************.********8874442256************************************44444455555555555566 PP

                   ......-EEEEEEE.EE--GGGGGSBHHHHHHHHHHHHHHHHHHH....ST..T-..S-EEEEEEE-SSEE-SBTT--EE-S--TT---TT-TTSBH CS
  Hexokinase_1  79 ......kveitqek.ykipeelktgtaeeLFdfiakciaefleeegeekkeekee..eelplGftFSFPveqtsldegtlirwtKgfaikdvegkdv 166
                         +v++t ek ++i+e+lk+++ +eLF +i++ciae+++++  +++ ++ e  + +++G+ +  P++q+sl+ +tl++++Kgf+i ++   d+
    EEA19805.1 106 rqvghsRVRRTLEKaWRIEERLKQDEPHELFLWIGNCIAEVVKDDLLSNAGSDVEqpAFIETGIALGLPIRQDSLEAATLMQTGKGFTI-GTDL-DL 200
                   666666*****************************************998887668899******************************.6666.** PP

                   HHHHHHHHHHTT......................-S.EEEEEEE-HHHHHHHHHHH CS
  Hexokinase_1 167 vqllqealerkg......................lp.vkvvalvNDTvgtllslaY 199
                   +q + +++er++                      lp +k++al+ND+v+tllsl+Y
    EEA19805.1 201 RQSILQGYERHTrrrsdsedeettraakrqrhyiLPqLKIIALTNDAVATLLSLSY 256
                   *********************************8755*****************99 PP

>> Hexokinase_2  Hexokinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  130.9   0.0   5.6e-42     5e-38       2     239 ..     268     599 ..     267     600 .. 0.87

  Alignments for each domain:
  == domain 1  score: 130.9 bits;  conditional E-value: 5.6e-42
                   EEEEESSSEEEEEEEEGGG-GGGTTTS.....-TTSEEEEE--GGGTTT.T-S.S-..--HHHHHHHHHSSSTTS-HHHHCCSHHHHHHHHHHHHHH CS
  Hexokinase_2   2 iGlIlGtGtNacyleklsnieklegkk.....eksgemviNtEwgafgd.egk.lpllrtkyDkeldeespnpgeqlfEkmiSGmYLGelvrlvlld 91 
                   +G++l+ G+Na++ + ls+++  +g +     +++ + ++ tEw  +       ++ ++tk+D  ld++s++pg+q++E+m++G+Y+Gel+r + ld
    EEA19805.1 268 MGIVLDEGCNATIPMTLSDLHPSKGRNilsqePTAAQTLVSTEWTLYSAsAPLrEHGILTKWDLLLDARSTRPGFQPLEYMTGGRYIGELIRIICLD 364
                   9********************77777799999888999********99865557999**************************************** PP

                   HHC.T.SSSC.....CCCSTTSS-THHHHHHHC--BTT-HHHHHHHHHCCS....................---..-HHHHHHHHHHHHHHHHHHHH CS
  Hexokinase_2  92 lieek.llfkgkse.klktpysldteflseieedesedleevrevleellg....................lesv.teedleivrevceavsrRaar 165
                   ++ +  ++ ++  +  l ++y l+te++  i +  +  l+++ ++l++ ++                    +  + t e ++++re +++v +R+a+
    EEA19805.1 365 YFVNVlGIAEKYLPsPLTQSYALRTETIISIISA-QLPLQTLVNTLNHSHAttaaaagnidflppppypteW--SwTIETANALRETAQSVQTRSAA 458
                   **8754666444336********99999888865.5557777777777555677888899999988854333..15********************* PP

                   HHCHHHHHHHHH-....................................................................SSEEEEEESHHHHHST CS
  Hexokinase_2 166 lvAagiaallkklgk...............................................................eekekvtvgvdGslyekyp 199
                   lvAa++++ll   ++                                                                  e+ +v++ G+++++yp
    EEA19805.1 459 LVAAATVGLLASNHEvslqdpnipssisasqfsietqflstspsksfhefsfglpssssskisagggggndgrrrdwfGGPEELVVACIGGIIQHYP 555
                   ***********977789999**********************************************9999988888884456788************ PP

                   THHHHHHHHHHHH.HT--S....-SEEEEE---TTTHHHHHHHH CS
  Hexokinase_2 200 kfrerlqealrel.lgeepe...kkvklklaedGsgvGAAliaa 239
                   +++e +q+++++l ++  p+   k+v l+ a dG ++GA+++a 
    EEA19805.1 556 NYKENCQRYIDRLlIKGGPQeggKSVFLREATDGVIIGAGVLAG 599
                   *************5333333778******************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (603 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       467  (0.0260472); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.26s 00:00:00.87 Elapsed: 00:00:00.46
# Mc/sec: 3933.71
//
Query:       EEA19806.1  [L=142]
Description: CBF/NF-Y family transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.5e-18   66.1   0.5    6.2e-18   64.9   0.5    1.6  1  CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) a
      1e-06   29.1   1.0    1.3e-06   28.8   0.1    1.6  2  Histone        Core histone H2A/H2B/H3/H4
  ------ inclusion threshold ------
      0.018   15.1   0.1      0.024   14.7   0.1    1.2  1  SPOB_ab        Sporulation initiation phospho-transferase B, 
       0.02   14.9   0.0       0.03   14.3   0.0    1.3  1  Bromo_TP       Bromodomain associated
       0.05   13.8   0.5      0.065   13.4   0.5    1.2  1  DUF5333        Family of unknown function (DUF5333)


Domain annotation for each model (and alignments):
>> CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) and archaeal histone
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.9   0.5   1.7e-21   6.2e-18       2      65 .]      13      79 ..      12      79 .. 0.96

  Alignments for each domain:
  == domain 1  score: 64.9 bits;  conditional E-value: 1.7e-21
                   XXXHHHHHHHHHCC..TTXS-.B-HHHHHHHHHHHHHHHHHHHHHHHHHHCCTTSSCE-HHHHHHHH CS
  CBFD_NFYB_HMF  2 eLPiarvkkImksd..pdark.iakdAkeliaecveefieelaseAaeickkekrKtikaehiklAv 65
                   +LP+a+v+kI+ +   p++++ +akdA++l+ ec++efi+ ++seA++i +ke +Kti+ eh+++A+
     EEA19806.1 13 SLPKATVQKIITEIlpPSTGQtFAKDARDLLMECCVEFITLISSEANDISEKEAKKTIACEHVEKAL 79
                   7*************97777778*******************************************97 PP

>> Histone  Core histone H2A/H2B/H3/H4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.8   0.1   3.7e-10   1.3e-06      52     129 ..       4      80 ..       1      82 [. 0.95
   2 ?   -1.6   0.1      0.88   3.2e+03      12      15 ..     105     108 ..      94     129 .. 0.48

  Alignments for each domain:
  == domain 1  score: 28.8 bits;  conditional E-value: 3.7e-10
                 HHHHHXXSXXSXHHHHHHHHHHHH.TTSSSXEEXHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTXSEEXHHHHHHHHH CS
     Histone  52 rkyqkstdlliqklpfaRvvreivksekedlrisaeavlalqealEallvelfeeAnllakhaKRvTitpkDiqlArr 129
                 r+ + + dl  +k+ ++++++ei +  ++++ + ++a ++l e +  +++ + +eAn ++++  ++Ti  ++++ A+r
  EEA19806.1   4 REFSANDDLSLPKATVQKIITEILP-PSTGQTFAKDARDLLMECCVEFITLISSEANDISEKEAKKTIACEHVEKALR 80 
                 5667899*****************9.**************************************************98 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.88
                 XXEE CS
     Histone  12 sekt 15 
                 +ek+
  EEA19806.1 105 REKK 108
                 1111 PP

>> SPOB_ab  Sporulation initiation phospho-transferase B, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   0.1   6.7e-06     0.024      32     112 ..      38     122 ..      25     123 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 6.7e-06
                 GGHHHHHHHHHHHHHHHHHHB-SSS-EEEEEEE..--SSSSEE.EEE.EEES-B.S-GGGHHHHHH..H-BTTBEEEEEEE-SSEE CS
     SPOB_ab  32 aydekLvelvrklfslldeavsqssenhlliti..eldengvr.lff.DfqGvl.tkleelekllkkleeeesvevkefevteeel 112
                 ++ + L+e++ ++++l+   ++  se ++  ti  e+ e+ +r l f D+ G + +  ee +++lk   e++++++++  +t eel
  EEA19806.1  38 DARDLLMECCVEFITLISSEANDISEKEAKKTIacEHVEKALRdLGFgDYIGEVlAVAEEHKEALKT-REKKASKMEQSGLTAEEL 122
                 556789********************9999999666666555436566****885789999999995.999999*99999999886 PP

>> Bromo_TP  Bromodomain associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   8.5e-06      0.03       7      73 ..      18      84 ..      13      87 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 8.5e-06
                HHHHHHHHHHHHHT-SEE-HHHHHHHHHHHHHHHHHHHHHHHHHHTTSS-SS--HHHHHHHHHHTT- CS
    Bromo_TP  7 llkvvvsqileeaGfdsaeesaLEtLteiaqkYirelgeqaksfaehagRseptlkDvvltLqelgi 73
                + +++++ il  +    + + a ++L+e   ++i+ ++ +a+  +e +++ +   + v+ +L +lg+
  EEA19806.1 18 TVQKIITEILPPSTGQTFAKDARDLLMECCVEFITLISSEANDISEKEAKKTIACEHVEKALRDLGF 84
                55677777775443388899999******************************************98 PP

>> DUF5333  Family of unknown function (DUF5333)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.5   1.8e-05     0.065      21      86 ..      53     120 ..      37     136 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 1.8e-05
     DUF5333  21 eirkeCdsisarllkalseleslkakarelGYse..aeieayvddkaekarlraeaeaylaakGvkag 86 
                  i++e ++is +  k     e++++ +r+lG+++   e+ a+ ++++e  + r+++++ ++++G++a+
  EEA19806.1  53 LISSEANDISEKEAKKTIACEHVEKALRDLGFGDyiGEVLAVAEEHKEALKTREKKASKMEQSGLTAE 120
                 689999***************************9445999************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (142 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1055  (0.0588432); expected 358.6 (0.02)
Passed bias filter:                      519  (0.0289475); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 968.30
//
Query:       EEA19807.1  [L=155]
Description: CBF/NF-Y family transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.5e-16   58.6   0.8    1.4e-15   57.3   0.8    1.7  1  CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) a
    0.00019   21.8   0.1    0.00019   21.8   0.1    1.7  2  Histone        Core histone H2A/H2B/H3/H4
  ------ inclusion threshold ------
      0.023   14.8   0.1      0.031   14.4   0.1    1.2  1  SPOB_ab        Sporulation initiation phospho-transferase B, 
      0.026   14.5   0.0      0.038   14.0   0.0    1.3  1  Bromo_TP       Bromodomain associated
      0.058   13.6   0.5      0.082   13.1   0.5    1.3  1  DUF5333        Family of unknown function (DUF5333)


Domain annotation for each model (and alignments):
>> CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) and archaeal histone
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.3   0.8   3.9e-19   1.4e-15       5      65 .]      29      92 ..      28      92 .. 0.95

  Alignments for each domain:
  == domain 1  score: 57.3 bits;  conditional E-value: 3.9e-19
                   HHHHHHHHHCC..TTXS-.B-HHHHHHHHHHHHHHHHHHHHHHHHHHCCTTSSCE-HHHHHHHH CS
  CBFD_NFYB_HMF  5 iarvkkImksd..pdark.iakdAkeliaecveefieelaseAaeickkekrKtikaehiklAv 65
                   ia+v+kI+ +   p++++ +akdA++l+ ec++efi+ ++seA++i +ke +Kti+ eh+++A+
     EEA19807.1 29 IATVQKIITEIlpPSTGQtFAKDARDLLMECCVEFITLISSEANDISEKEAKKTIACEHVEKAL 92
                   79*********97777778*******************************************97 PP

>> Histone  Core histone H2A/H2B/H3/H4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   0.1   5.2e-08   0.00019      65     129 ..      30      93 ..       7      95 .. 0.94
   2 ?   -1.9   0.2       1.1   3.9e+03      12      15 ..     118     121 ..     107     141 .. 0.48

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 5.2e-08
                 HHHHHHHHHHH.TTSSSXEEXHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTXSEEXHHHHHHHHH CS
     Histone  65 lpfaRvvreivksekedlrisaeavlalqealEallvelfeeAnllakhaKRvTitpkDiqlArr 129
                 + ++++++ei +  ++++ + ++a ++l e +  +++ + +eAn ++++  ++Ti  ++++ A+r
  EEA19807.1  30 ATVQKIITEILP-PSTGQTFAKDARDLLMECCVEFITLISSEANDISEKEAKKTIACEHVEKALR 93 
                 678999999999.**************************************************98 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 1.1
                 XXEE CS
     Histone  12 sekt 15 
                 +ek+
  EEA19807.1 118 REKK 121
                 1111 PP

>> SPOB_ab  Sporulation initiation phospho-transferase B, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.1   8.5e-06     0.031      32     112 ..      51     135 ..      38     136 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 8.5e-06
                 GGHHHHHHHHHHHHHHHHHHB-SSS-EEEEEEE..--SSSSEE.EEE.EEES-B.S-GGGHHHHHH..H-BTTBEEEEEEE-SSEE CS
     SPOB_ab  32 aydekLvelvrklfslldeavsqssenhlliti..eldengvr.lff.DfqGvl.tkleelekllkkleeeesvevkefevteeel 112
                 ++ + L+e++ ++++l+   ++  se ++  ti  e+ e+ +r l f D+ G + +  ee +++lk   e++++++++  +t eel
  EEA19807.1  51 DARDLLMECCVEFITLISSEANDISEKEAKKTIacEHVEKALRdLGFgDYIGEVlAVAEEHKEALKT-REKKASKMEQSGLTAEEL 135
                 556789********************9999999666666555436566****885789999999995.999999*99999999886 PP

>> Bromo_TP  Bromodomain associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   1.1e-05     0.038       8      73 ..      32      97 ..      25     100 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1.1e-05
                HHHHHHHHHHHHT-SEE-HHHHHHHHHHHHHHHHHHHHHHHHHHTTSS-SS--HHHHHHHHHHTT- CS
    Bromo_TP  8 lkvvvsqileeaGfdsaeesaLEtLteiaqkYirelgeqaksfaehagRseptlkDvvltLqelgi 73
                 +++++ il  +    + + a ++L+e   ++i+ ++ +a+  +e +++ +   + v+ +L +lg+
  EEA19807.1 32 VQKIITEILPPSTGQTFAKDARDLLMECCVEFITLISSEANDISEKEAKKTIACEHVEKALRDLGF 97
                5667777775443388889999******************************************98 PP

>> DUF5333  Family of unknown function (DUF5333)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.5   2.3e-05     0.082      21      86 ..      66     133 ..      50     149 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2.3e-05
     DUF5333  21 eirkeCdsisarllkalseleslkakarelGYse..aeieayvddkaekarlraeaeaylaakGvkag 86 
                  i++e ++is +  k     e++++ +r+lG+++   e+ a+ ++++e  + r+++++ ++++G++a+
  EEA19807.1  66 LISSEANDISEKEAKKTIACEHVEKALRDLGFGDyiGEVLAVAEEHKEALKTREKKASKMEQSGLTAE 133
                 689999***************************9445999********9***************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (155 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1209  (0.0674327); expected 358.6 (0.02)
Passed bias filter:                      601  (0.0335211); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.47
# Mc/sec: 1001.64
//
Query:       EEA19808.1  [L=256]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-39  135.9   0.0    1.3e-39  135.6   0.0    1.0  1  adh_short     short chain dehydrogenase
    2.3e-23   83.0   0.0    2.8e-23   82.7   0.0    1.1  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
    8.7e-10   38.8   0.0    1.2e-09   38.4   0.0    1.1  1  KR            KR domain
  ------ inclusion threshold ------
      0.089   12.2   0.0       0.41   10.1   0.0    2.0  1  Epimerase     NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  135.6   0.0     3e-43   1.3e-39       1     193 [.       4     194 ..       4     196 .. 0.93

  Alignments for each domain:
  == domain 1  score: 135.6 bits;  conditional E-value: 3e-43
                 SEEEEESTTSHHHHHHHHHHHHT..T-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHH.SSESEEEE---S.S--SSGGG CS
   adh_short   1 kvvlvtGassGIGraiakelake..GakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkkl.gkldvLvnNAGi.tgsgpfse 95 
                 k+++vtGas+G+G+ai+k l++     ++++++rs e+l+++++++ ++   + +i++D+td++   ++ve a  k+ g+ld Lv N Gi  +++ + +
  EEA19808.1   4 KTIIVTGASRGLGLAISKYLLTTtpPNNIIALARSVEPLQALKNQFPDN---VEYIAGDLTDQTIGARAVELALTKFgGHLDGLVLNHGIlGQVSVIGK 99 
                 79*****************997632578888**************9987...*************************99***********777777778 PP

                 CSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHHCTH CS
   adh_short  96 lseeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakelrek 193
                  ++e w+  ++vNl++++  t a+lpa l++s G+I+++sS a+  +  g+a+Y+A+Kaa++ ++ +l++e  +  ++ +a+ PG+vdT+m++e+re+
  EEA19808.1 100 ADAELWKHGFDVNLFSLVAFTTAALPA-LRKSHGKIIFTSSGAATSATTGWACYGATKAALNYFALALSQEEPD--VTSIALRPGMVDTEMQREIRED 194
                 88888**********************.67***************************************99877..9******************997 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.7   0.0   6.3e-27   2.8e-23       1     224 [.      10     241 ..      10     247 .. 0.83

  Alignments for each domain:
  == domain 1  score: 82.7 bits;  conditional E-value: 6.3e-27
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSEE..EE--TTSHHHHHHHHHHHHHHH.SSEEEEEE-----EGCSS-GGGH-HHH CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneeakkrveelaeelgaev..lecDVtdeeqvealveevvekf.gklDilvnnagiapklkgpfletsree 94 
                   Ga +g+G ai k l        +  l ++  + +++l+++++ +v  ++ D td++  +++ve +  kf g+lD+lv n gi  +  + + +++ e 
    EEA19808.1  10 GASRGLGLAISKYLLTTTPPNNIIALARSV-EPLQALKNQFPDNVeyIAGDLTDQTIGARAVELALTKFgGHLDGLVLNHGILGQ-VSVIGKADAEL 104
                   677788888887776665444444444443.4599*******88777**********************99**************.7888889**** PP

                   HHHHHHHHTHHHHHHHHHHHHHCTSC.CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTTHHH... CS
  adh_short_C2  95 fdraldvnlyslfllakaalplmkeg.gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikgfde... 187
                   +++ +dvnl sl++++ aalp+++++ g+i+ +ss +a+ ++++ + yga+Kaal+ ++ +l  +  +  ++  a  pg+++T+++++i++ ++   
    EEA19808.1 105 WKHGFDVNLFSLVAFTTAALPALRKShGKIIFTSSGAATSATTGWACYGATKAALNYFALAL--SQEEPDVTSIALRPGMVDTEMQREIREDHAkkg 199
                   *********************666655*****************************996555..4555669999999************98443233 PP

                   .....HHHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--S CS
  adh_short_C2 188 .....lleelearaplgrlgtpeevaeaalfLasdeasyitG 224
                         l + e+ +  g+l +pe+ +++++ L+ d+ +  +G
    EEA19808.1 200 elppgALTRYEEAYRDGKLLKPEQPGNVMARLVLDAPKELSG 241
                   444447888899999999999999999999999888776666 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.4   0.0   2.6e-13   1.2e-09       2     176 ..       5     179 ..       4     182 .. 0.91

  Alignments for each domain:
  == domain 1  score: 38.4 bits;  conditional E-value: 2.6e-13
                 EEEEETTTSHHHHHHHHHHHHHH.S-EEEEE-SS..--HHHHHHHHHHHHT.T-EEEE----TT-HHHHHHHHHHHHHHS.S---EEEE-------.-- CS
          KR   2 tylitGGlGgLGlelarwlaekg.arhlvllsRsaaadedskaliaeleal.gaevevvaaDvsdkdavealleeikaee.ppikGvihaAgvlrd.kl 96 
                 t ++tG+  gLGl++++ l+     ++++ l+Rs        + +++l+++   +ve++a D++d++  ++++e + +++ + + G +   g+l + + 
  EEA19808.1   5 TIIVTGASRGLGLAISKYLLTTTpPNNIIALARSV-------EPLQALKNQfPDNVEYIAGDLTDQTIGARAVELALTKFgGHLDGLVLNHGILGQvSV 96 
                 679*****************99989*********3.......466777777577***********************9999******999999975267 PP

                 TTT--HHHHHHHHTTTTHHHHHHHHHTTT...S--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHHHHHTEEEEEE- CS
          KR  97 leemtaedleqvlapKvkGawnLhelled...esldffvlfSSiagllgsagqanYaaaNaflDalaeyrrsqglpavsinwg 176
                 + + +ae +++ +   +  +    ++  +   +s   ++++SS a++  ++g a Y a+ a l+ +a   ++++  ++si++ 
  EEA19808.1  97 IGKADAELWKHGFDVNLFSLVAFTTAALPalrKSHGKIIFTSSGAATSATTGWACYGATKAALNYFALALSQEEPDVTSIALR 179
                 889999**************99999887778899999*******************************************986 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   9.2e-05      0.41       1      59 [.       6      69 ..       6     194 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 9.2e-05
                EEEETTTSHHHHHHHHHHHHCT..SEEEEEES-STTTTCHHCHHC.....EEEE--TT-HHHHHHH CS
   Epimerase  1 ilVtGatGfiGsalvkallekg..yevigldrlssasntarledl.....elveldltdrsalerl 59
                i+VtGa+  +G a+ k+ll+ +   ++i+l+r  +    ++l++      e + +dltd++  +r+
  EEA19808.1  6 IIVTGASRGLGLAISKYLLTTTppNNIIALARSVEP--LQALKNQfpdnvEYIAGDLTDQTIGARA 69
                89*******************99666****999443..3333333578889********9854444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (256 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       388  (0.0216409); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.51u 0.30s 00:00:00.81 Elapsed: 00:00:00.48
# Mc/sec: 1593.52
//
Query:       EEA19809.1  [L=289]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.1e-34  116.8   0.0      1e-33  116.5   0.0    1.1  1  adh_short     short chain dehydrogenase
    1.4e-22   80.4   0.0    1.7e-22   80.1   0.0    1.1  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
      1e-06   28.8   0.0    1.5e-06   28.3   0.0    1.1  1  KR            KR domain


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.5   0.0   1.7e-37     1e-33      10     193 ..      46     227 ..      44     229 .. 0.93

  Alignments for each domain:
  == domain 1  score: 116.5 bits;  conditional E-value: 1.7e-37
                 SHHHHHHHHHHHHT..T-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHH.SSESEEEE---S.S--SSGGGCSHHHHHHH CS
   adh_short  10 sGIGraiakelake..GakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkkl.gkldvLvnNAGi.tgsgpfselseeewerv 104
                  G+G+ai+k l++     ++++++rs e+l+++++++ ++   + +i++D+td++   ++ve a  k+ g+ld Lv N Gi  +++ + + ++e w+  
  EEA19809.1  46 TGLGLAISKYLLTTtpPNNIIALARSVEPLQALKNQFPDN---VEYIAGDLTDQTIGARAVELALTKFgGHLDGLVLNHGIlGQVSVIGKADAELWKHG 141
                 69********997632578888**************9987...*************************99***********77777777888888**** PP

                 HHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHHCTH CS
   adh_short 105 ievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakelrek 193
                 ++vNl++++  t a+lpa l++s G+I+++sS a+  +  g+a+Y+A+Kaa++ ++ +l++e  +  ++ +a+ PG+vdT+m++e+re+
  EEA19809.1 142 FDVNLFSLVAFTTAALPA-LRKSHGKIIFTSSGAATSATTGWACYGATKAALNYFALALSQEEPD--VTSIALRPGMVDTEMQREIRED 227
                 ******************.67***************************************99877..9******************997 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.1   0.0   2.9e-26   1.7e-22      32     224 ..      73     274 ..      47     280 .. 0.86

  Alignments for each domain:
  == domain 1  score: 80.1 bits;  conditional E-value: 2.9e-26
                   HHHHHHHHHTTSEE..EE--TTSHHHHHHHHHHHHHHH.SSEEEEEE-----EGCSS-GGGH-HHHHHHHHHHHTHHHHHHHHHHHHHCTSC.CEEE CS
  adh_short_C2  32 krveelaeelgaev..lecDVtdeeqvealveevvekf.gklDilvnnagiapklkgpfletsreefdraldvnlyslfllakaalplmkeg.gsiv 124
                   + +++l+++++ +v  ++ D td++  +++ve +  kf g+lD+lv n gi  +  + + +++ e +++ +dvnl sl++++ aalp+++++ g+i+
    EEA19809.1  73 EPLQALKNQFPDNVeyIAGDLTDQTIGARAVELALTKFgGHLDGLVLNHGILGQ-VSVIGKADAELWKHGFDVNLFSLVAFTTAALPALRKShGKII 168
                   4578999999988667**********************99**************.7888889*************************666655**** PP

                   EEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTTHHH........HHHHHHHHSTTSS-B-HHHHHHHHHH CS
  adh_short_C2 125 nlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikgfde........lleelearaplgrlgtpeevaeaalf 213
                    +ss +a+ ++++ + yga+Kaal+ ++ +l  +  +  ++  a  pg+++T+++++i++ ++         l + e+ +  g+l +pe+ +++++ 
    EEA19809.1 169 FTSSGAATSATTGWACYGATKAALNYFALAL--SQEEPDVTSIALRPGMVDTEMQREIREDHAkkgelppgALTRYEEAYRDGKLLKPEQPGNVMAR 263
                   *************************996555..4555669999999************984432334444478888999999999999999999999 PP

                   HCSGGGTT--S CS
  adh_short_C2 214 LasdeasyitG 224
                   L+ d+ +  +G
    EEA19809.1 264 LVLDAPKELSG 274
                   99888776666 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.3   0.0   2.5e-10   1.5e-06      11     176 ..      47     212 ..      45     215 .. 0.91

  Alignments for each domain:
  == domain 1  score: 28.3 bits;  conditional E-value: 2.5e-10
                 HHHHHHHHHHHHHH.S-EEEEE-SS..--HHHHHHHHHHHHT.T-EEEE----TT-HHHHHHHHHHHHHHS.S---EEEE-------.--TTT--HHHH CS
          KR  11 gLGlelarwlaekg.arhlvllsRsaaadedskaliaeleal.gaevevvaaDvsdkdavealleeikaee.ppikGvihaAgvlrd.klleemtaedl 105
                 gLGl++++ l+     ++++ l+Rs        + +++l+++   +ve++a D++d++  ++++e + +++ + + G +   g+l + + + + +ae +
  EEA19809.1  47 GLGLAISKYLLTTTpPNNIIALARSV-------EPLQALKNQfPDNVEYIAGDLTDQTIGARAVELALTKFgGHLDGLVLNHGILGQvSVIGKADAELW 138
                 8**********999899********3.......466777777577***********************9999******999999975267889999*** PP

                 HHHHTTTTHHHHHHHHHTTT...S--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHHHHHTEEEEEE- CS
          KR 106 eqvlapKvkGawnLhelled...esldffvlfSSiagllgsagqanYaaaNaflDalaeyrrsqglpavsinwg 176
                 ++ +   +  +    ++  +   +s   ++++SS a++  ++g a Y a+ a l+ +a   ++++  ++si++ 
  EEA19809.1 139 KHGFDVNLFSLVAFTTAALPalrKSHGKIIFTSSGAATSATTGWACYGATKAALNYFALALSQEEPDVTSIALR 212
                 ***********99999887778899999*******************************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (289 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       331  (0.0184617); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.43u 0.22s 00:00:00.65 Elapsed: 00:00:00.38
# Mc/sec: 2273.69
//
Query:       EEA19810.1  [L=441]
Description: FAD dependent oxidoreductase superfamily [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.4e-44  151.0   0.2    7.3e-44  150.8   0.2    1.0  1  DAO             FAD dependent oxidoreductase
    6.9e-05   22.2   0.1       0.23   10.6   0.0    2.2  2  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    0.00068   20.2   0.2      0.053   14.1   0.0    2.6  2  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
     0.0034   17.6   0.2     0.0076   16.4   0.2    1.6  1  NAD_binding_8   NAD(P)-binding Rossmann-like domain
  ------ inclusion threshold ------
      0.021   14.1   0.3       0.37   10.0   0.0    2.2  2  FAD_binding_3   FAD binding domain
        0.1   11.4   0.1         11    4.7   0.0    2.1  2  Trp_halogenase  Tryptophan halogenase


Domain annotation for each model (and alignments):
>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  150.8   0.2   2.5e-47   7.3e-44       2     352 .]       3     426 ..       2     426 .. 0.74

  Alignments for each domain:
  == domain 1  score: 150.8 bits;  conditional E-value: 2.5e-47
                 EEEECTSHHHHHHHHHH........HHTT..EEEEESSSSTTSSGGGSSEEEEESSSSTHHSTHHHHHHHHHHHHHH.HHHHHHHSSTTSEEEEEEEEE CS
         DAO   2 vviiGGGiiGlstAyeL........arrg..VtllekgdiagsgaSgrnsgllhsglrylpeaselarlslealeel.releeelgididyrrtGllsl 89 
                  viiGGGi+G+s+A++L        a +g  + ++e+++++ sgaSg ++g+++  +  ++ a  l +ls+e+++ l +e++++++  ++y + + lsl
  EEA19810.1   3 TVIIGGGIMGASVAHYLgdpssssnALQGheIHVIESSSQLFSGASGYAAGFIAKDWFAPALA-PLGKLSYELHKKLaAEYDGNRR--WGYMPGTALSL 98 
                 69***************9999887766779***********9***************744444.5667777777777777777644..****9999999 PP

                 ESS............HHHHHH.HHHHHHHH.HHTTTTE.EEEEHHHHHHHSTTSTTTSEEEEETTE.EEEEHHHHHHHHHHHHHHTT-EEEESECEEEE CS
         DAO  90 aad............eeelea.ldkllall.leaglda.elldaeevrelepalpgllgalfypdt.gqvdpakltaalaraaealGveilegtevtgl 172
                   +               +++ +++l+a++ +   l+  e+l++++ ++le         + + dt gqvdp +l+++l ++  a+Gv+ ++ ++v+++
  EEA19810.1  99 DVNttdngnggtgydW-LRDGsSRALAASGtKTVKLEKpEWLTKQKEERLE--------VISDEDTvGQVDPLRLCHFLHETTTARGVKWHNPAQVVSV 188
                 7432222222222221.1222122333333544455444888886344444........34444545*******************************9 PP

                 EEEE...TCEEEEE...EECT.EEEEEEEEEEE--GGGHHHH.HTT.CTT...T.SEEEEEEEEEEEEEECCTHSTGSGCSEEEEE........EEETT CS
         DAO 173 eeed...gkvwgve...rttp.gendaadavVnaaGawsdll.gll.kel...d.lpispvrgqvlvlkplseklvspaailpvpe........tdddg 250
                    d   + ++ v     +t+ +   a++ +V++aG+w++l+ ++l +     d + +s + g++l ++ +  ++++++ ++              d+g
  EEA19810.1 189 TT-DpatNCISSVTvlnSETQtEYSIACRNLVICAGPWTSLVyKTLfPSAsttDsPHVSSLAGYSLLVRSPRHTMLHEHDQYKGQThavfttvsEEDGG 286
                 44.335755555555564444333347899**********998777755566744888**********666666766656666655777889999**** PP

                 TTEEEEEETTSEEEE.EESSE....EETTCSS.TSCSHHHHHHHHHHHHHHSGGG..........CGEE..EEEEEEEEE.TTSSEEEEEEE....... CS
         DAO 251 rgvyvtprkdgrvlv.Ggtad....eesgddd.pevdeedidellealrklfPql..........gdvl..rkwaGlrpl.pdglpligetp....... 323
                 ++++++ r + ++++ G + +    +++++++    de++ ++l++ + +++ +l          +d++  r+  ++rp    glp++ ++        
  EEA19810.1 287 FSPEIFSRQGAEIYIaGLNSTeiplPTGAEGSkEIMDEQQMAKLRKVAVRFLGKLaadneepineDDLEtlREGLCFRPVsNTGLPIVSRVKdellgek 385
                 ********999****5555548887555444445678888888*********774444444555444554478889***53799******7799***** PP

                 ............TEEEEEEEEECTTTHHHHHHHHHHHHHHH CS
         DAO 324 ............gvkglylatGhsghGltlapatGkllael 352
                             +  g+++ tGh+ +G++++++tGk++a++
  EEA19810.1 386 invrsdttavgrEIGGVFIGTGHGPWGISQSLGTGKVIADM 426
                 **********98777************************97 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.5   0.0   0.00018      0.53       3     178 ..       3      44 ..       1      78 [. 0.64
   2 !   10.6   0.0   7.8e-05      0.23     168     236 ..     147     223 ..     125     231 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00018
                  EEEE--SHHHHHHHHHHHH........HTS-EEEEETTHCHHHCSHHHHCHHHHHHHHHHHHHHHHHCHHHHCCCCHCCTCEEEEESCEEEEETEEEC CS
                  xxxxxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2   3 vvviGgGpAGlaaaltlaq........agakvtlvelegtclnggcllskallgvaedaeiasevvkklnqgielllgeevvkidpgkkkvklekkke 92 
                   v+iGgG+ G ++a++l+         +                                                                      
   EEA19810.1   3 TVIIGGGIMGASVAHYLGDpssssnalQ---------------------------------------------------------------------- 30 
                  4555555555555555555444444433...................................................................... PP

                  TCEEEEEESEEEE---EEE-BCTCTTC.TTBEECCSECHHHHHHCCSS-TSEEEEES-SHHHHHHHHHHHHHT-EEEEEESSSSSS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  93 gdeekiaydklvlAtGssprdlgipGvaenvgklvrtldsaealklkllpkrivvvGgGyiGvElAaalaklgkevtlveardrll 178
                                                                                          g+e++++e  ++l 
   EEA19810.1  31 ------------------------------------------------------------------------GHEIHVIESSSQLF 44 
                  ........................................................................44555555555544 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 7.8e-05
                  EEEEESSSSSSTTS-HHHHHHHHHHHHHTTEEEEESCEEEEEEETTE.....EEEEEETTSCE...EEESEEEE-S- CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxx...xxxxxxxxxxx RF
  Pyr_redox_2 168 vtlveardrllraldkelsaaleealekeGvevklgtsvkeidgnge.....klevvledgee...idadlvvvavG 236
                    ++ + d++ +  + +l  +l+e  +++Gv+++  ++v+ ++ ++      +++v +++ ++   i+++ +v+++G
   EEA19810.1 147 LEVISDEDTVGQVDPLRLCHFLHETTTARGVKWHNPAQVVSVTTDPAtncisSVTVLNSETQTeysIACRNLVICAG 223
                  567777888877777889999************************999998766644444444678*********99 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.1   0.0   1.8e-05     0.053       2      35 ..       3      44 ..       2      58 .. 0.85
   2 ?    3.3   0.0      0.04   1.2e+02      24      72 ..     146     194 ..     137     204 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 1.8e-05
                EEEECSSHHHHHHHHHH.......HH.TTSEEEEEESSSSSS CS
   Pyr_redox  2 vvvvGgGyiglElAgal.......ae.lgkkVtvversdkll 35
                 v++GgG  g  +A +l       ++  g++++v+e s++l 
  EEA19810.1  3 TVIIGGGIMGASVAHYLgdpssssNAlQGHEIHVIESSSQLF 44
                79*******************998552569*********998 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.04
                 EEEEEESSSSSSTTSSHHHHHHHHHHHHHTTEEEECSEEEEEEEEETTS CS
   Pyr_redox  24 kVtvversdkllrllDeeaskilqeklekngievllntkveeiegsedg 72 
                 +  v+  +d++ ++ +  +   l+e  +++g++ +  ++v+++++++ +
  EEA19810.1 146 RLEVISDEDTVGQVDPLRLCHFLHETTTARGVKWHNPAQVVSVTTDPAT 194
                 567788888888666778899999999*****************99864 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.2   2.6e-06    0.0076       1      31 [.       5      43 ..       5      60 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 2.6e-06
                   EE--SHHHHHHHHHHHC........CTEEEEEE-SSSSS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLak........agfdvlllekrdrl 31
                   I+G+G+ G++ A++L +        +g++++++e++++l
     EEA19810.1  5 IIGGGIMGASVAHYLGDpssssnalQGHEIHVIESSSQL 43
                   9**************96555554445*********9985 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.1     0.032        95       4      21 ..       3      20 ..       1      41 [. 0.90
   2 ?   10.0   0.0   0.00012      0.37      94     169 ..     151     229 ..     113     295 .. 0.75

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.032
                   EEEE--SHHHHHHHHHHH CS
  FAD_binding_3  4 VlIVGaGpaGlmlallLs 21
                   ++I+G+G  G++ a+ L 
     EEA19810.1  3 TVIIGGGIMGASVAHYLG 20
                   78************9996 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00012
                    HCST-CEE--HHHHHHHHHHHHHHHTEEETCSEEEECCEECCCC...CCCEEEECCTTEEEEEEEEEEEE--GTT-HHH CS
  FAD_binding_3  94 sspervtvypqteleriLvehaeerglqvrfktevesleqdeeg...vtaevrdketgeeetvrakYlvGaDGgrStvr 169
                    s   +v  +   +l   L e  ++rg++ +  ++v+s++ d  +    + +v+++et++e+ + ++ lv + G ++   
     EEA19810.1 151 SDEDTVGQVDPLRLCHFLHETTTARGVKWHNPAQVVSVTTDPATnciSSVTVLNSETQTEYSIACRNLVICAGPWTSLV 229
                    44455555555667788999*******************99877332467888********************986443 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.1    0.0038        11       3      34 ..       4      40 ..       2      47 .. 0.75
   2 ?    4.7   0.0    0.0038        11     150     208 ..     158     223 ..     113     242 .. 0.70

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.0038
                    EEE--SHHHHHHHHHH......HHHTTTSSEEEEEE-S CS
  Trp_halogenase  3 vivGGGtaGwlaAaal......akalkgklevtlvese 34
                    vi+GGG+ G  +A +l      ++al+g +e+ ++es+
      EEA19810.1  4 VIIGGGIMGASVAHYLgdpsssSNALQG-HEIHVIESS 40
                    9***************333322235533.999999986 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.0038
                     EE-HHHHHHHHHHHHHHCT-EEEE.--EEEEEE-T.TS-EEEEEETT.....S-EEE-SEEEE-SG CS
  Trp_halogenase 150 hldaalyakfLrrvaearGvtrve.gkvvevqlde.dgrveslrled.....greveadlfiDcsG 208
                     ++d  ++ +fL++  +arGv+  + ++vv+v++d+ ++ ++s+++ +     + ++  +  + c G
      EEA19810.1 158 QVDPLRLCHFLHETTTARGVKWHNpAQVVSVTTDPaTNCISSVTVLNsetqtEYSIACRNLVICAG 223
                     88999999************9654399********9999999986443223344444444455555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (441 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       352  (0.019633); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.49u 0.25s 00:00:00.74 Elapsed: 00:00:00.40
# Mc/sec: 3322.79
//
Query:       EEA19811.1  [L=344]
Description: DNA repair protein Nse1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-71  240.7   1.1    1.6e-71  240.2   1.1    1.2  1  SMC_Nse1      Nse1 non-SMC component of SMC5-6 complex
    3.9e-14   52.7   9.6    6.1e-14   52.0   9.6    1.3  1  zf-RING-like  RING-like domain
     0.0017   18.6   7.7     0.0027   18.0   7.7    1.3  1  zf-RING_2     Ring finger domain
      0.006   16.7   0.0      0.016   15.3   0.0    1.7  1  AbiEi_4       Transcriptional regulator, AbiEi antitoxin
     0.0069   16.5   0.0      0.013   15.6   0.0    1.6  1  DUF2161       Putative PD-(D/E)XK phosphodiesterase (DUF2161)
  ------ inclusion threshold ------
      0.017   15.1   2.3      0.029   14.4   2.3    1.3  1  zf-ANAPC11    Anaphase-promoting complex subunit 11 RING-H2 f
       0.05   14.3   2.9      0.098   13.3   2.2    1.8  2  FYDLN_acid    Protein of unknown function (FYDLN_acid)
       0.17   12.1   2.5       0.38   10.9   2.5    1.6  1  zf-HC5HC2H_2  PHD-zinc-finger like domain
       0.44   10.8   6.0        1.3    9.3   6.1    1.7  1  zf-HC5HC2H    PHD-like zinc-binding domain
       0.59   10.3   4.3        1.6    9.0   4.2    1.7  1  FANCL_C       FANCL C-terminal domain
       0.68    9.6   4.2        1.1    8.9   4.2    1.3  1  Zn_ribbon_17  Zinc-ribbon, C4HC2 type
        1.6    8.6   6.3        2.8    7.9   6.3    1.4  1  zf-C3HC4_2    Zinc finger, C3HC4 type (RING finger)
        2.4    8.1   6.5        4.2    7.3   6.5    1.4  1  zf-C3HC4      Zinc finger, C3HC4 type (RING finger)
        7.1    7.1   6.3         61    4.2   0.0    3.6  3  VlpA_repeat   Mycoplasma hyorhinis VlpA repeat
        9.6    6.5   8.5    1.1e+02    3.1   8.5    2.5  1  CTU2          Cytoplasmic tRNA 2-thiolation protein 2


Domain annotation for each model (and alignments):
>> SMC_Nse1  Nse1 non-SMC component of SMC5-6 complex
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  240.2   1.1   1.3e-74   1.6e-71       1     194 []      14     217 ..      14     217 .. 0.91

  Alignments for each domain:
  == domain 1  score: 240.2 bits;  conditional E-value: 1.3e-74
    SMC_Nse1   1 nralLQallargilteeelkkvlaailsae..eevspeditqedleeyiakinealspldyeirsvrhqlg.........k...ervyyalVNttsdee 85 
                 nra+LQa++ar+++t++e+k+vlaai+sa+  +ev +editq+dl++yia++n+a+sp+d+eirs++ q+          +    ++ yalVNttsd+ 
  EEA19811.1  14 NRAFLQAFMARSTMTFDEAKPVLAAIFSAQenREVLAEDITQADLNSYIAAANSAISPFDLEIRSAKPQIAldnannntgSantAQIVYALVNTTSDPL 112
                 7*****************************8888888**********************************87776655505567777*********** PP

    SMC_Nse1  86 tklATtfsaeeiafiKrlldamfetsntrrlevmaitesqavvlelarilaaaraerrstelsqeeaaadkgLtaseaeklLkrLveegWleksreGfy 184
                 t+lATt++++eiaf+Krlldamfet+ntrr+e+m+++++qa  ++la++ + +++++ ste++++ ++a+++Lt  +ae++L+rLveegW+eks++Gfy
  EEA19811.1 113 TQLATTYTVDEIAFVKRLLDAMFETHNTRRSEAMVLSNIQA--IQLAKVSS-SSSNSPSTENANQ-SGAAQSLTIPQAETMLARLVEEGWFEKSAKGFY 207
                 *****************************************..*****444.4344446665554.68******************************* PP

    SMC_Nse1 185 sLdlRallEL 194
                 sL++R l+EL
  EEA19811.1 208 SLSPRGLMEL 217
                 *********9 PP

>> zf-RING-like  RING-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.0   9.6   5.1e-17   6.1e-14       1      43 []     241     283 ..     241     283 .. 1.00

  Alignments for each domain:
  == domain 1  score: 52.0 bits;  conditional E-value: 5.1e-17
  zf-RING-like   1 CeaCkeivtqGvrCsnesCnvrlHvdCfqhyirthsskkCpkC 43 
                   C+aC++i+t+G+rCsn++C+ rlH+ C+++++r ++s++Cp C
    EEA19811.1 241 CAACRDIITVGQRCSNRDCTGRLHDTCVRNFFRMQQSERCPVC 283
                   ******************************************* PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   7.7   2.2e-06    0.0027       3      44 .]     241     284 ..     239     284 .. 0.91

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 2.2e-06
   zf-RING_2   3 CpICleelssadsvlllpCgHvfhreClerwlrssst..CPlCr 44 
                 C+ C + ++ ++++   +C    h +C+++++r +++  CP+C+
  EEA19811.1 241 CAACRDIITVGQRCSNRDCTGRLHDTCVRNFFRMQQSerCPVCK 284
                 9**************999*999********977777777****7 PP

>> AbiEi_4  Transcriptional regulator, AbiEi antitoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   1.4e-05     0.016      26      46 ..     187     207 ..     184     210 .. 0.89

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 1.4e-05
     AbiEi_4  26 psalrrLvrkGwLvrlrrGvY 46 
                 +++l+rLv++Gw ++ ++G+Y
  EEA19811.1 187 ETMLARLVEEGWFEKSAKGFY 207
                 467****************** PP

>> DUF2161  Putative PD-(D/E)XK phosphodiesterase (DUF2161)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   1.1e-05     0.013      79     114 ..     178     214 ..     140     216 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 1.1e-05
     DUF2161  79 kkatgeekaakiLrkny.YgWFerverGvYrlteaGr 114
                 ++  + ++a+++L++ +  gWFe+ ++G Y+l++ G 
  EEA19811.1 178 AQSLTIPQAETMLARLVeEGWFEKSAKGFYSLSPRGL 214
                 44455678899998877358**************995 PP

>> zf-ANAPC11  Anaphase-promoting complex subunit 11 RING-H2 finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   2.3   2.4e-05     0.029      25      81 ..     234     287 ..     214     291 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 2.4e-05
                 TTT-SBTTS--TTCSTTTTTS-EEEBTTS-EEEHHHHHHHHHHHSTSSB-TTTSSB- CS
  zf-ANAPC11  25 GicrvsfdGtcpsckfpGddcplvlGkckhnfhlhcilkwletetskglcpmcrqtf 81 
                    r++f  +c +  + G+ c+     c+  +h+ c+ +++  ++s+ +cp+c+  +
  EEA19811.1 234 RGKRIKFCAACRDIITVGQRCSN--RDCTGRLHDTCVRNFFRMQQSE-RCPVCKADW 287
                 346999***************95..68***************99985.8****9876 PP

>> FYDLN_acid  Protein of unknown function (FYDLN_acid)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       7.4   8.8e+03      62      62 ..     180     180 ..     147     233 .. 0.56
   2 ?   13.3   2.2   8.2e-05     0.098      13      90 ..     265     341 ..     259     344 .] 0.62

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 7.4
  FYDLN_acid  62 e 62 
                 +
  EEA19811.1 180 S 180
                 1 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 8.2e-05
  FYDLN_acid  13 pscgakFYDLnkdPivcpkcgeefepeevlksraaaaeaeea.kkkkeeeedeedeeeeedvsdedadeeeeedddddv 90 
                  +c + F+ ++++   cp c++ ++ ++ + +ra +++++    ++++++++++++  ++ +++ +++++e e+d+d +
  EEA19811.1 265 DTCVRNFFRMQQS-ERCPVCKADWPGDKYVGERAITTTEQYMqGRRRSANTAAARQSGVNGQTNGETEDDEGEEDED-E 341
                 6788888888776.58************9777777666555424555555666666666655554444444333332.2 PP

>> zf-HC5HC2H_2  PHD-zinc-finger like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   2.5   0.00032      0.38      56      87 ..     239     270 ..     226     288 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00032
  zf-HC5HC2H_2  56 ekCllCkkrkGaciqCskkeCktafHvtCala 87 
                   + C+ C++   +  +Cs+++C+   H tC ++
    EEA19811.1 239 KFCAACRDIITVGQRCSNRDCTGRLHDTCVRN 270
                   67*******99999***************986 PP

>> zf-HC5HC2H  PHD-like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   6.1    0.0011       1.3      36      68 ..     238     270 ..     226     285 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.0011
  zf-HC5HC2H  36 klkCylCkkkvGaciqCskkkCkkafHvtCake 68 
                  + C  C++ + +  +Cs+++C+ + H tC ++
  EEA19811.1 238 IKFCAACRDIITVGQRCSNRDCTGRLHDTCVRN 270
                 467***************************976 PP

>> FANCL_C  FANCL C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   4.2    0.0013       1.6      19      48 ..     250     279 ..     236     286 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.0013
                 --B--S-TT----B-SGGGHHHHHHHHSSS CS
     FANCL_C  19 pdisCdnekCnkkfHsaCLkeWlrslkesr 48 
                   + C n  C+ + H +C+ +++r +++ r
  EEA19811.1 250 VGQRCSNRDCTGRLHDTCVRNFFRMQQSER 279
                 4578********************998876 PP

>> Zn_ribbon_17  Zinc-ribbon, C4HC2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   4.2   0.00095       1.1       4      47 ..     238     282 ..     235     285 .. 0.84

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00095
  Zn_ribbon_17   4 lksCayCe.lavkgrvvlcgvCeHvlHasCarewfenddlaeCps 47 
                   +k Ca C  +   g+ +    C   lH  C+r+ f +++++ Cp+
    EEA19811.1 238 IKFCAACRdIITVGQRCSNRDCTGRLHDTCVRNFFRMQQSERCPV 282
                   678999962555577778899**********************97 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   6.3    0.0023       2.8       2      40 .]     241     283 ..     240     283 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0023
  zf-C3HC4_2   2 CpiCldmlkdpsvvt..pCgHvfCqkCilr..sLeekneCPlC 40 
                 C+ C d +  + +     C  + +  C++    ++++++CP+C
  EEA19811.1 241 CAACRDIITVGQRCSnrDCTGRLHDTCVRNffRMQQSERCPVC 283
                 999999999998877779*9999999999866689999***** PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   6.5    0.0035       4.2       1      41 []     241     283 ..     241     283 .. 0.90

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0035
                 -TTT-S--SS-E...E-TTS--B-CHHHHHHHHCTSSB--TTT CS
    zf-C3HC4   1 CpiCleeakepn..elleCkHsfCskCirkilksrkkvkCPlC 41 
                 C+ C + ++  +     +C+ +++ +C+r+  + ++++ CP+C
  EEA19811.1 241 CAACRDIITVGQrcSNRDCTGRLHDTCVRNFFRMQQSERCPVC 283
                 999999998888667889***************999999**** PP

>> VlpA_repeat  Mycoplasma hyorhinis VlpA repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.0     0.051        61       2      10 ..     137     145 ..     136     146 .. 0.90
   2 ?    3.3   0.5     0.098   1.2e+02       2      10 ..     169     177 ..     168     178 .. 0.90
   3 ?   -0.1   0.2       1.3   1.5e+03       6       9 ..     275     278 ..     274     279 .. 0.92

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.051
  VlpA_repeat   2 TENTQQSEA 10 
                  T NT  SEA
   EEA19811.1 137 THNTRRSEA 145
                  89******9 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.098
  VlpA_repeat   2 TENTQQSEA 10 
                  TEN  QS A
   EEA19811.1 169 TENANQSGA 177
                  9******87 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 1.3
  VlpA_repeat   6 QQSE 9  
                  QQSE
   EEA19811.1 275 QQSE 278
                  ***9 PP

>> CTU2  Cytoplasmic tRNA 2-thiolation protein 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   8.5     0.092   1.1e+02      41      91 ..     266     323 ..     137     343 .. 0.74

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.092
        CTU2  41 e.......letsekCalCglplddkakewkrtitiselseteseeekeelekakeeee 91 
                 +       +++se+C++C+++   ++   +r+it +e+  + ++++ ++  + ++  +
  EEA19811.1 266 TcvrnffrMQQSERCPVCKADWPGDKYVGERAITTTEQYMQGRRRSANTAAARQSGVN 323
                 04444555899***********888888899999988886666655333332222211 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (344 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       933  (0.0520386); expected 358.6 (0.02)
Passed bias filter:                      496  (0.0276647); expected 358.6 (0.02)
Passed Vit filter:                        76  (0.00423894); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 2251.59
//
Query:       EEA19812.1  [L=1039]
Description: alpha,alpha-trehalose glucohydrolase TreA/Ath1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.8e-32  112.2   0.0    6.2e-32  111.1   0.0    1.6  1  Glyco_hydro_65N  Glycosyl hydrolase family 65, N-terminal dom
    2.2e-23   82.8   5.9    1.9e-18   66.5   1.5    2.3  2  Glyco_hydro_65m  Glycosyl hydrolase family 65 central catalyt
    0.00019   21.2   0.1    0.00055   19.8   0.1    1.9  1  Glyco_hydro_65C  Glycosyl hydrolase family 65, C-terminal dom
     0.0028   17.8   2.8      0.024   14.8   0.4    3.0  2  F5_F8_type_C     F5/8 type C domain
  ------ inclusion threshold ------
      0.015   15.8   0.1        8.5    7.0   0.0    3.0  3  F420_oxidored    NADP oxidoreductase coenzyme F420-dependent


Domain annotation for each model (and alignments):
>> Glyco_hydro_65N  Glycosyl hydrolase family 65, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.1   0.0   1.7e-35   6.2e-32       9     227 ..      77     341 ..      73     342 .. 0.81

  Alignments for each domain:
  == domain 1  score: 111.1 bits;  conditional E-value: 1.7e-35
                      --HHHHHHT-EE-SSEEE----TT...TT--.....................-EEETT-EE-T........T.....SSS-EE----EEEEEEE CS
  Glyco_hydro_65N   9 eeglrEslftlGNGylGtRgafee...eysdp....................gtyiaGvYdreiseeanGyp.....eeneelvnlpdwlglrl 74 
                      ++g++Es+ +++NGy+G+++a  +   e                        ++ +aG+Yd ++++++ ++p      +   +  +p+w gl l
       EEA19812.1  77 DQGHYESRGSVANGYIGLNVAGAGpffE---LdtavegdvingwplfsrrqtFAGLAGFYDLQPTTNGTNFPwlyqyGDDSVISGVPHWGGLVL 167
                      599*******************994331...033445567777889999999999********7755555442221122235779********* PP

                      EETTEE.--G..GGSEEEEEEEEEETTTTEEEEEEEEE-TTS.-EEEEEEEEEE-SSSTTEEEEEEEEEESS--EEEEEEEEEETT--B..... CS
  Glyco_hydro_65N  75 rvdgee.ldl..degeildyereLdlreGvltrsltwrspag.kevrveserfvsladrhlaairlevtplnfsgevevesgldgdvan.ekh. 162
                       ++g+e ld+  d+++i+dy+ + d+++Gvl+++++w++++   ++++ ++ f+++ d+++a++rl++tp  ++g  +v++++dg+ a+ +++ 
       EEA19812.1 168 DLGGGEyLDAtvDNATISDYTTTYDYKAGVLSWDYKWSPKNSsGSFQIGYKIFANKLDVNQAVVRLSITPS-ANGSASVVNVIDGYSAVrTDFv 260
                      **9988877755778***********************999899**************************6.8****************63335 PP

                      ........EEEEETTSS.......-EEEEEEEEEEEETTEE--SEE.......SEEEEEEEEEE-TT-EEEEEEEEEEEET CS
  Glyco_hydro_65N 163 .kdprka.levrtresg.......itvavaartrveasgeklevee.......ekiaqtlsvelkagetvtleKyvavats 227
                       ++++++ +++++++ g       i  a+  +  +++s+++l +++       ++iaq+++v+++ag+t+ ++K+v+ a++
       EEA19812.1 261 sSGNESDvIFTAVKPVGvnnvtawIYAALDGDDAFDFSSATLVNDKpyvhnndSSIAQSVNVKFTAGTTIAITKFVGAAST 341
                      4333333799999999977777776666666666666666666655999999*************************9986 PP

>> Glyco_hydro_65m  Glycosyl hydrolase family 65 central catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.5   1.5   5.2e-22   1.9e-18      17     209 ..     433     621 ..     422     639 .. 0.83
   2 !   18.2   0.3   2.5e-07   0.00091     269     334 ..     640     708 ..     622     724 .. 0.75

  Alignments for each domain:
  == domain 1  score: 66.5 bits;  conditional E-value: 5.2e-22
  Glyco_hydro_65m  17 rldvgakGltGegYrGhvfWDtElfvlPlylltepevarnlLeyRynrleaArekAkek..........glkGAlyPwesasdGeEesqelhln 100
                      + +++  Glt + Y G+vfWD+++++ P + ++ pe a+ + +yR++   +A  +Ak +              A+y w s++ G  ++      
       EEA19812.1 433 DWSISVGGLTSDSYAGQVFWDADVWMQPGLVAAFPESAKRITNYRVAIYAQALANAKTAytssqnqssfSSDAAIYSWTSGRYG-NCT------ 519
                      4468889**************************************987777777776431111111111345899*******99.666...... PP

  Glyco_hydro_65m 101 irsgewepdaseeeiHvnaaiayavvqYveatgDeefleeeglellvetarfWasraeldkdkgryeidgviGPdEYeenvdnNaytnliaawn 194
                       +   w       e+H+n++i   +v+ + ++gD++  +++ + +   +a ++ ++ + +     y++++++ PdEY +nvd   yt ++  ++
       EEA19812.1 520 ATGPCWD-----YEYHLNGDIGISLVNQWVVSGDTKTFQNTHFPIYNSIATLYGDLLKKNG--SYYTLTNMTDPDEYANNVDAGGYTMTLISQT 606
                      3444777.....9*******************************************99887..79***************************** PP

  Glyco_hydro_65m 195 lelalealeeleeea 209
                      l+ a    +++   +
       EEA19812.1 607 LSNANTFRKQFGLDE 621
                      ***999999887764 PP

  == domain 2  score: 18.2 bits;  conditional E-value: 2.5e-07
  Glyco_hydro_65m 269 lkaegdkvlesqviKQaDvllllyllke..efseeqikanldfYeprtv.hdSslSalvhaivaaelgk 334
                       + e++ +++s ++KQaDv+l+++ l++  +++++     ld+Y  + + ++  +  ++++iva ++  
       EEA19812.1 640 VTLEYTTMNNSVAVKQADVILSTFPLDYtkNYTTSAALNDLDYYALKQSpDGPGMTYAIFSIVANDVSP 708
                      578999*******************765116777788889****8766615678999999999988865 PP

>> Glyco_hydro_65C  Glycosyl hydrolase family 65, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.1   1.5e-07   0.00055       1      47 [.     782     828 ..     782     832 .. 0.86

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 1.5e-07
                      ----TT-SEEEEE.EEETTEEEEEEEESSEEEEEEESSSTEEEEETTE CS
  Glyco_hydro_65C   1 PrLPeeWdglsFr.lryRGrrLrVrvtpeevtvtlesgepltievyGe 47 
                      P+LP+++ ++++r +++RG+ ++ + + +++t++  + +  ++  +++
       EEA19812.1 782 PNLPPQIPSVKYRtFYWRGWPIQAASNYTHTTIQRAT-TVTPLSTADK 828
                      9********************************9885.5555555555 PP

>> F5_F8_type_C  F5/8 type C domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.1     0.095   3.4e+02      63      86 ..     610     636 ..     604     661 .. 0.65
   2 !   14.8   0.4   6.6e-06     0.024       8      73 ..     887     950 ..     878     994 .. 0.74

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.095
                   EEEEEEEEESS.SSSEEEEEEECE..E CS
  F5_F8_type_C  63 vksykiqvsdd.getWttvkdekv..p 86 
                   + +++ q+ +d ++tWt+ +d+     
    EEA19812.1 610 ANTFRKQFGLDeNKTWTEMADNILviR 636
                   5677778999989*******9443332 PP

  == domain 2  score: 14.8 bits;  conditional E-value: 6.6e-06
                   SSTTTGGGGGGSSSTTSSEEESSSSTTEEEEEEE..EEEEEEEEEEEEECSSTTSSEEEEEEEEEESS CS
  F5_F8_type_C   8 esgewpaaaaldGnkntaWsssssddkqwlqvdL..gkpkkidgvvtqgrqdggnayvksykiqvsdd 73 
                   +++++ +  a+dG  +t+W ++ + + + l+vdL   ++ +++g+ ++++     a ++++++   + 
    EEA19812.1 887 YQPGQYPISAVDGAASTKWQPKFAANVSSLTVDLtaSNANTVSGFYFDWA----QAPPTNVTVVLHNS 950
                   4455567889**********9999999*******777789**********....56666666666555 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   0.0    0.0087        31      54      81 ..     258     285 ..     235     293 .. 0.81
   2 ?   -3.9   0.0         5   1.8e+04       8      22 ..     533     547 ..     533     551 .. 0.87
   3 ?    7.0   0.0    0.0024       8.5      47      81 ..     641     675 ..     593     681 .. 0.75

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.0087
                    CHHHHHHH-SEEEE-S-HHHHHHHHHHC CS
  F420_oxidored  54 dneeaaeeadvvvlavkpedveevlsel 81 
                    d     +e+dv++ avkp  v +v + +
     EEA19812.1 258 DFVSSGNESDVIFTAVKPVGVNNVTAWI 285
                    55566689***********999998755 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 5
                    SHHHHHHHHHHHHTT CS
  F420_oxidored   8 Gnmgealasgllaag 22 
                    G++g +l+++++ +g
     EEA19812.1 533 GDIGISLVNQWVVSG 547
                    899********9998 PP

  == domain 3  score: 7.0 bits;  conditional E-value: 0.0024
                    C-EEECECHHHHHHH-SEEEE-S-HHHHHHHHHHC CS
  F420_oxidored  47 gvkvtavdneeaaeeadvvvlavkpedveevlsel 81 
                      + t+++n+ a+++adv++ +++  ++++  +++
     EEA19812.1 641 TLEYTTMNNSVAVKQADVILSTFPLDYTKNYTTSA 675
                    378899******************99998876665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1039 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       605  (0.0337442); expected 358.6 (0.02)
Passed bias filter:                      382  (0.0213063); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.74u 0.30s 00:00:01.04 Elapsed: 00:00:00.46
# Mc/sec: 6836.71
//
Query:       EEA19813.1  [L=237]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (237 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       373  (0.0208043); expected 358.6 (0.02)
Passed bias filter:                      301  (0.0167884); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.25s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 1676.04
//
Query:       EEA19814.1  [L=945]
Description: subtilisin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.6e-25   87.8   0.0    1.5e-24   86.8   0.0    1.3  1  Peptidase_S8  Subtilase family


Domain annotation for each model (and alignments):
>> Peptidase_S8  Subtilase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.8   0.0   8.2e-29   1.5e-24       4     271 ..     658     884 ..     657     915 .. 0.81

  Alignments for each domain:
  == domain 1  score: 86.8 bits;  conditional E-value: 8.2e-29
                   -EEEEECS-B-TT-TTTGGGEEE..EEEE---TTSG.GGEETT..-SS-TT-SC-SSS....HHHHHHHHHH-B..SSSSSB-SSTTSEEEEEE-SS CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8   4 vlvavlDtGvdpshpdlsvttdgerklvdvideegagfngads..ettstnwarddngnsieHGthvAGiaaanapeegekngvapgakilsvkvld 98 
                   v++a+lDtG+d++hpd+ + t++              + g+ +  ++  +++ +d ng    HGt +AG+ +             p+a+++ +k+ d
    EEA19814.1 658 VKIAILDTGIDQTHPDIDACTEQ--------------IKGQYNwtNEKFPKHVDDHNG----HGTFTAGLLLEY----------LPDAELYIAKISD 726
                   79**************9944444..............444444004444566666667....*********999..........9***********9 PP

                   TTSB-HH..HHHHHHHHHHHH.CT-SEEEE-EE.SCETTCHHCHHHHHHHHHHHH.CCT-EEEEE--SS-T-HHEEE-TTCEECTTTSTTCEEEEEE CS
                   xxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8  99 tsggsmetgteliraieeaae.dkvdvinmslg.estslpktgrsiealainravnkkgvlvviSaGNngktgsslqagspvgtpstsknvitvgay 193
                   ++  s    +++++ai++a+   +vd+i+ms+g  + + +++++     ai +a  ++ +l+ ++a N+g       a+ +  +p+  +nvi + ++
    EEA19814.1 727 GNPCSP---ENIAKAIDYAIDeWNVDIISMSFGfPTREIKDYDKLEG--AIHKAY-SNHTLLFAAASNSG-------ANLDRAYPARDENVICIHST 810
                   999999...89**********99**********44445566666555..999999.8899999999****.......9*********9********* PP

                   STTSSB-TT--B-TT.......-EEEE-S-CCCCCCCCCHHHTTTHHEEEE-SHHHCHHHHHHHHHHHHHHHTT--HH CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8 194 ttegkiapfSsrGpssdgklkpdivapGgnivstwsrqsnnsaglssyqsmsGTSmAsPnaagaaAlllsalpkltpe 271
                   + +g+ + fS +  +        ++  G+++ s+w+ +  ++ ++ +++++sGTS+A+P a ++aA ll++   + p+
    EEA19814.1 811 DANGNRSKFSPTALAD----ALNLATVGEAVESSWPLRLCEGNNSLGTKYKSGTSFATPIAVSIAAFLLQYVRTYVPD 884
                   **********666643....467777777777******977777777***********************87774443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (945 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       557  (0.031067); expected 358.6 (0.02)
Passed bias filter:                      465  (0.0259356); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.69u 0.31s 00:00:01.00 Elapsed: 00:00:00.45
# Mc/sec: 6363.46
//
Query:       EEA19815.1  [L=1425]
Description: protein phosphatase-1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.5e-35  122.4   0.1    6.7e-35  121.4   0.1    1.5  1  Metallophos  Calcineurin-like phosphoesterase
    5.1e-18   64.3   0.4    8.6e-12   44.5   0.0    3.0  3  TPR_10       Tetratricopeptide repeat
    2.4e-13   50.3   1.5      7e-13   48.8   1.5    1.9  1  STPPase_N    Serine-threonine protein phosphatase N-terminal 
      2e-11   44.0   0.0    5.3e-11   42.7   0.0    1.8  1  TPR_12       Tetratricopeptide repeat
    1.8e-05   24.5   0.1      0.079   13.0   0.0    2.8  2  TPR_7        Tetratricopeptide repeat
     0.0002   21.2  12.6    0.00057   19.7  12.6    1.8  1  PHD          PHD-finger
  ------ inclusion threshold ------
      0.019   15.3   0.0        5.1    7.7   0.0    2.8  2  TPR_17       Tetratricopeptide repeat
       0.13   12.2   0.1        7.5    6.6   0.0    2.6  2  TPR_1        Tetratricopeptide repeat
       0.14   12.3   0.1        6.1    7.2   0.0    2.7  2  TPR_2        Tetratricopeptide repeat
       0.35   10.8  11.2       0.49   10.4   9.2    2.3  2  Prok-RING_1  Prokaryotic RING finger family 1
       0.36   10.4   6.0       0.91    9.1   6.0    1.7  1  PHD_2        PHD-finger


Domain annotation for each model (and alignments):
>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.4   0.1   4.1e-38   6.7e-35       2     201 ..    1172    1363 ..    1171    1366 .. 0.93

  Alignments for each domain:
  == domain 1  score: 121.4 bits;  conditional E-value: 4.1e-38
                   EEEEEESBTBTTCCTHHHHHHHHHHHH..HHHTTESEEEEESTSSSSS..HHHHHHHHHHHHHHHHTSEEEEEC-TTS........CHHHHHHHHH CS
  Metallophos    2 rilvigDlHlalgggqlddllkllddl..lreekpdlvllaGDlvdrg..dlekellellaalvkypipvylllGNHe........gfeeellnky 85  
                   ++ ++gD+H     gq+ dll++++    +++ +++l+l  GD+vdrg  +le+ +l ll++++kyp++++ll+GNHe        gf +e++++ 
   EEA19815.1 1172 PVKIVGDIH-----GQYTDLLRMFELSgyPPN-ENYLFL--GDYVDRGksGLET-ILLLLCYKLKYPDNFFLLRGNHEcanitrlgGFFDECKRRC 1258
                   5789*****.....**********66664666.99****..*******778888.77779********************9999999999999997 PP

                   HHHHHHHHHHEHHHCEEETSEEEEEETTEEEEEEEESE.CEEETHHHHHHHHHHHSCHHHHCC...HHHHHHHHHHTTCSEEEEEESSESSCSSSC CS
  Metallophos   86 gylgifsepwrsdaevfnnlplaslgsgslkvlllhGg.spellvsldklgslnleleapepg...dewlkdlekrekadwvivlgHsplyrgsgy 177 
                          ++w+++++vfn+lp+a+ + +  k++++hGg sp l  + ++++++ +++++p+ g   d++++d       + +i   +  ++rg +y
   EEA19815.1 1259 N-----VKIWKTFVDVFNCLPVAAVVAD--KIFCVHGGlSPSL-SHMNDIRGIARPTDVPDYGlltDLLWSD-------PALIDEDWESNERGVSY 1339
                   7.....99********************..********65555.****************************.......999999999******** PP

                   SCCHHHHHHHHHHTTESEEEEESS CS
  Metallophos  178 lfgdealedllkkygvdlvisGHt 201 
                   +fg ++++++l k++ dl++++H 
   EEA19815.1 1340 VFGKNVIREFLTKFDFDLICRAHM 1363
                   ***********************7 PP

>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0       8.9   1.5e+04      27      41 ..     656     670 ..     650     670 .. 0.78
   2 !   44.5   0.0   5.3e-15   8.6e-12       1      41 [.     672     712 ..     672     713 .. 0.98
   3 !   16.9   0.1   2.7e-06    0.0044       1      23 [.     714     736 ..     714     740 .. 0.89

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 8.9
      TPR_10  27 ealairrrllGpdHP 41 
                 + +++++ +l+++ P
  EEA19815.1 656 QLIEAWKTVLEAENP 670
                 678999999998766 PP

  == domain 2  score: 44.5 bits;  conditional E-value: 5.3e-15
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHP 41 
                 t++s+ NLa ++r++gr++eAe+l  +++++r+ +lG++HP
  EEA19815.1 672 TMTSMENLASTYRNQGRWNEAEKLEVQVMETRKTVLGAEHP 712
                 789*************************************9 PP

  == domain 3  score: 16.9 bits;  conditional E-value: 2.7e-06
      TPR_10   1 tAsslnNLanalrqrgrydeAea 23 
                 t++s+ NLa ++r++gr++e e+
  EEA19815.1 714 TLTSMANLASTYRNQGRWNEVEK 736
                 89****************99555 PP

>> STPPase_N  Serine-threonine protein phosphatase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.8   1.5   4.3e-16     7e-13       1      47 [.    1124    1169 ..    1124    1170 .. 0.92

  Alignments for each domain:
  == domain 1  score: 48.8 bits;  conditional E-value: 4.3e-16
   STPPase_N    1 vDdiIerLlevrgkpggkkvqLseaEIrqlCakareiFLsQPtLLeL 47  
                  +Dd+I+rL++   + ++++++++++EIr lCa +re++LsQP+LLeL
  EEA19815.1 1124 LDDMIQRLIAS-PRAASRTLCIRNEEIRTLCAVSRELLLSQPVLLEL 1169
                  7********83.477779****************************9 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.7   0.0   3.2e-14   5.3e-11       2      65 ..     672     735 ..     658     738 .. 0.94

  Alignments for each domain:
  == domain 1  score: 42.7 bits;  conditional E-value: 3.2e-14
      TPR_12   2 vatalnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAl 65 
                 ++t++ nla+++r +gr+ eA++l  +++e ++ +lG +hp t+t++ nL+ +yr +gr+ e +
  EEA19815.1 672 TMTSMENLASTYRNQGRWNEAEKLEVQVMETRKTVLGAEHPSTLTSMANLASTYRNQGRWNEVE 735
                 567777*****************************************************99866 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.0   0.0   4.8e-05     0.079       3      31 ..     677     705 ..     675     710 .. 0.78
   2 !    8.7   0.0    0.0012       1.9       2      19 ..     718     735 ..     717     737 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 4.8e-05
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLaltkd 31 
                  nLa++y+++G++ eA++l  q+++++k 
  EEA19815.1 677 ENLASTYRNQGRWNEAEKLEVQVMETRKT 705
                 59**************9986666666555 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.0012
       TPR_7   2 LlnLarlysrlGdyeeAi 19 
                   nLa++y+++G++ e +
  EEA19815.1 718 MANLASTYRNQGRWNEVE 735
                 57************9876 PP

>> PHD  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7  12.6   3.5e-07   0.00057       2      51 ..     747     790 ..     746     791 .. 0.89

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 3.5e-07
                 BTTTTSTTSTTSCEEEETTTSCEEETTTSSSTHSHHSHHSSTBSSTTTHT CS
         PHD   2 CavCkkksdeeeelvqCdgCkrwfHqkClkppleseekpegewlCekCke 51 
                 C +C   +d+++++++C++C++ +H++C+  +++   +p+ e +C  C++
  EEA19815.1 747 C-ICAF-DDHDGDIIFCESCETYQHTECYYHDQN---VPH-EHFCADCSP 790
                 8.****.9*********************99977...444.79*****86 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.0    0.0031       5.1      14      34 .]     674     694 ..     662     694 .. 0.85
   2 ?    4.4   0.0     0.035        57      15      30 ..     717     732 ..     711     736 .. 0.87

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0031
      TPR_17  14 daynnLAelllknGdlmtArq 34 
                  ++ nLA +++++G++ +A++
  EEA19815.1 674 TSMENLASTYRNQGRWNEAEK 694
                 6899**************985 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.035
      TPR_17  15 aynnLAelllknGdlm 30 
                 ++ nLA +++++G++ 
  EEA19815.1 717 SMANLASTYRNQGRWN 732
                 799**********976 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   0.0    0.0046       7.5       6      22 ..     678     694 ..     677     695 .. 0.94
   2 ?    2.7   0.0     0.076   1.2e+02       6      20 ..     720     734 ..     717     737 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.0046
                 HHHHHHHHTT-HHHHHH CS
       TPR_1   6 nlGnayfklgkydeAle 22 
                 nl+ +y+++g+++eA++
  EEA19815.1 678 NLASTYRNQGRWNEAEK 694
                 9**************97 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.076
                 HHHHHHHHTT-HHHH CS
       TPR_1   6 nlGnayfklgkydeA 20 
                 nl+ +y+++g+++e 
  EEA19815.1 720 NLASTYRNQGRWNEV 734
                 9**********9985 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   0.0    0.0037       6.1       6      22 ..     678     694 ..     675     695 .. 0.90
   2 ?    1.9   0.0      0.18     3e+02       5      19 ..     719     733 ..     717     737 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0037
       TPR_2   6 nlGlayyklgdyeeAle 22 
                 nl+  y+++g+++eA++
  EEA19815.1 678 NLASTYRNQGRWNEAEK 694
                 89*************98 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.18
       TPR_2   5 ynlGlayyklgdyee 19 
                  nl+  y+++g+++e
  EEA19815.1 719 ANLASTYRNQGRWNE 733
                 589**********98 PP

>> Prok-RING_1  Prokaryotic RING finger family 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.0       8.2   1.3e+04      34      45 ..      14      25 ..      13      30 .. 0.81
   2 ?   10.4   9.2    0.0003      0.49      12      38 ..     749     776 ..     744     787 .. 0.77

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 8.2
  Prok-RING_1 34 CyekagkCvnee 45
                 C++ + +C++++
   EEA19815.1 14 CFNAFQQCLEKS 25
                 999999998765 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.0003
  Prok-RING_1  12 kelke.edDiVvCpeCgtpyHraCyeka 38 
                   ++++ + Di+ C  C t +H +Cy + 
   EEA19815.1 749 CAFDDhDGDIIFCESCETYQHTECYYHD 776
                  45554157*****************875 PP

>> PHD_2  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   6.0   0.00056      0.91       4      35 ..     758     788 ..     756     789 .. 0.88

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00056
       PHD_2   4 llsCdkCsvaVHasCYGvskesdgeeWlCrrC 35 
                 +++C +C++  H +CY   ++  + e  C+ C
  EEA19815.1 758 IIFCESCETYQHTECYYHDQNVPH-EHFCADC 788
                 8***************88888777.8999999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1425 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       758  (0.0422779); expected 358.6 (0.02)
Passed bias filter:                      479  (0.0267165); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.88u 0.32s 00:00:01.20 Elapsed: 00:00:00.48
# Mc/sec: 8918.99
//
Query:       EEA19816.1  [L=529]
Description: aromatic-L-amino-acid decarboxylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   8.2e-102  340.7   0.0     1e-101  340.4   0.0    1.1  1  Pyridoxal_deC    Pyridoxal-dependent decarboxylase conserved 
      7e-06   25.5   0.0    2.4e-05   23.8   0.0    1.6  1  Beta_elim_lyase  Beta-eliminating lyase
  ------ inclusion threshold ------
       0.11   12.7   0.0       0.35   11.1   0.0    1.9  2  AAA_22           AAA domain
       0.13   11.4   0.0       0.76    8.9   0.0    2.0  2  Aminotran_1_2    Aminotransferase class I and II


Domain annotation for each model (and alignments):
>> Pyridoxal_deC  Pyridoxal-dependent decarboxylase conserved domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  340.4   0.0  2.3e-105    1e-101       1     373 [.      35     430 ..      35     432 .. 0.92

  Alignments for each domain:
  == domain 1  score: 340.4 bits;  conditional E-value: 2.3e-105
                    TTTTGGGSCSSHHSSHH.HHHHHHHHHHCTGGGS--TTSTTBHCSSH....HHHHHHHHHHHHHT-BTSSTTTSHHHHHHHHHHHHHHHHHTT--G CS
  Pyridoxal_deC   1 PeylkrlldeaapekaesleqilediekilapgvttwhspefhkllpagnslisllgdlLadainkngftweesPaltelevvvldwlaellglpe 96 
                    P+yl+++++e+ p +++++ +i  die  ++pg+t+w+sp+f +++pa+  ++s+lg++ ++a n   f+w  sPa+tele++++dw+a+ lglp 
     EEA19816.1  35 PGYLRPQIPENPPVEPQEWSEIQADIESKIQPGLTHWQSPNFMAFFPAAVTYPSILGEMYSAAFNAPAFNWICSPACTELETIIMDWVAKALGLPG 130
                    9*********************************************************************************************** PP

                    GGTCC.T..-EEEEESSHHHHHHHHHHHHHHHHHHHH......HHHTTTS.HHHH...HCCEEEEEETTS-HHHHHHHHHHT-EEEEE-..-BTTT CS
  Pyridoxal_deC  97 eflek.e..gggvlqvgssestllallAartkvikem......kekgkelkeaei...ldklvlytsdqahssvekaalvlgvklrvip..ldeng 178
                     fl++ e  ggg++q ++ses    l+Aar++  +e+      k+ g +  e  +    ++lv+  sdqahss+ kaalv+g + r++p  l++n+
     EEA19816.1 131 CFLSTsEnrGGGIIQGTASESAATMLIAARERRARELtlaegvKDDGSREYEDRLcahRARLVALSSDQAHSSIAKAALVAGTRFRSVPakLEDNM 226
                    ****9659***********************999886222222555555555555222579***************************8335799* PP

                    BB-HHHHHHHHHHHH.CTT.EEEEEEEEBS-TTT-BB--HHHHHHHHHH....CT-EEEEE-TTGGGGGGSGGGGG.GGTTGGGESEEEEECCCCT CS
  Pyridoxal_deC 179 klrgaalekaieedk.ekGlipffvvatlGttvlgaFddlkelgdicek....ydlwlHvDAAyaGsaficpeirh.llkgieradSitvnphKll 268
                    ++ g++l++ + +++ e+Gl+pff++ tlGtt+++a d   el+ ++++      +w+H+DAAyaG+a++  e++h   +  e +dS+++n hK+l
     EEA19816.1 227 EMTGDSLRAVLTKVEeEEGLVPFFITFTLGTTNSCAVDRFAELKAVLNEkeswRRIWVHIDAAYAGAALVVDEYQHiAQNFAEGVDSFNMNMHKWL 322
                    *********999875268*******************************999889*********************6667789************* PP

                    S--SS-EEEEESSCCGCHHHH-EEECCCT.TT..TTTSEECCCGSSSSSGHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTT.EEE CS
  Pyridoxal_deC 269 lvlldcsalivkdkealqqalqleaeYLehed..sdvaadlgtkaiplsrrvrilklwfvlralGveglqnqirksvelakyleklirkder.fei 361
                    lv++d+s+l+v+++++l++al + ++YL+++    +   d+++++i l+rr+r+lk+wfv+r++G +g++++i+k + l+  ++++++ + + fei
     EEA19816.1 323 LVNFDASCLFVRNRTDLTNALDITPTYLRNPYseTGTVIDYRNWQISLGRRFRSLKIWFVMRSYGLNGMKAHIHKGLALGGLFTEKVKSRPDlFEI 418
                    *****************************877678999********************************************************** PP

                    CSTTBSSEEEEE CS
  Pyridoxal_deC 362 vaevelglVcFr 373
                    v+++ ++l + r
     EEA19816.1 419 VTKPDFALTVLR 430
                    ***999887766 PP

>> Beta_elim_lyase  Beta-eliminating lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.0   5.4e-09   2.4e-05      52     241 ..     129     382 ..     108     400 .. 0.67

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 5.4e-09
                      E.............ES-HHHHHHHHHHHH--TTEEEEEETT-HHHHSST.THHHHC...C--EEEEE-EBTT...................... CS
  Beta_elim_lyase  52 f.............vpqGtaAnsillkillqrgeevivtepahihfdet.gaiael...agvklrdlknkea...................... 106
                      +             + qGta++s + ++++ r+        a +  d   + ++       ++l+ l +++a                      
       EEA19816.1 129 PgcflstsenrgggIIQGTASESAATMLIAARERRARELTLAEGVKDDGsREYEDRlcaHRARLVALSSDQAhssiakaalvagtrfrsvpakl 222
                      4444555555555566777777777777776655544444455544444344333222244455555555555666666666666666666666 PP

                      ...TBE-HHHHHHHS--S-TTS-EEEEEEEESSBTTTTTB---HHHHHHHHHHHHHCT....-EEEEEETTHHHHH...HHHTS-CHHHHTTSS CS
  Beta_elim_lyase 107 ...GkmdlekleaaikevgaheekiklisltvTnntagGqvvsleelrevaaiakkyg....iplhlDgARfanaa...kslgeivkemfsyvD 190
                          +m+ ++l+a++++v++   + +l+   +T      +   ++  +e++a+ ++++    i +h+D+A  a aa    + ++i+++ +++vD
       EEA19816.1 223 ednMEMTGDSLRAVLTKVEE---EEGLVPFFITFTLGTTNSCAVDRFAELKAVLNEKEswrrIWVHIDAAY-AGAAlvvDEYQHIAQNFAEGVD 312
                      666788899********666...777777777777744666788999*******99999999********5.55555989999*********** PP

                      EEEEESSSTT--SS-EEEEE-HH........................HHHHHHHHHHHHT---SSTHHHHH CS
  Beta_elim_lyase 191 svtmslkKdllanvGgvlafrddel....................edylaerveqrkylggglrqagvlaa 241
                      s+ m + K ll+n ++ ++f ++                         +++r +q   lg ++r+  +  +
       EEA19816.1 313 SFNMNMHKWLLVNFDASCLFVRNRTdltnalditptylrnpysetGTVIDYRNWQI-SLGRRFRSLKIWFV 382
                      ***************65555555445788888888888888887655666665554.56777776666555 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       2.2   9.8e+03      55      75 ..     116     135 ..     103     159 .. 0.68
   2 ?   11.1   0.0   7.8e-05      0.35      71     118 ..     271     326 ..     197     352 .. 0.74

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 2.2
      AAA_22  55 dl.lrellralglelkaerlss 75 
                 ++ + ++++algl++    ls+
  EEA19816.1 116 TIiMDWVAKALGLPGCF--LST 135
                 44488999999999888..333 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 7.8e-05
      AAA_22  71 erlsseellealeqalraravielliiDEaqhlr....s......eealeeLrsllnl 118
                 + l+++e +++++ +++a+++ ++l++DE qh+     +      +++ ++L  l+n+
  EEA19816.1 271 AVLNEKESWRRIWVHIDAAYAGAALVVDEYQHIAqnfaEgvdsfnMNMHKWL--LVNF 326
                 467899999********99999**********97655414555556666666..5554 PP

>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.12   5.5e+02     208     236 ..     111     136 ..      91     167 .. 0.74
   2 ?    8.9   0.0   0.00017      0.76      91     195 ..     189     295 ..     177     324 .. 0.76

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.12
                    TTSTTEEEEEESSSTTSSGGG-EEEEEEE CS
  Aminotran_1_2 208 eeepnllivgslsKafGlaGeRvGyilgn 236
                     +e +++i+  ++Ka+Gl+G    +++ +
     EEA19816.1 111 CTELETIIMDWVAKALGLPG---CFLSTS 136
                    556678999999********...555554 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.00017
                    TTT-EEEEEESS-THHHHHHHHTTSEEEEEEBEETTTTEE-HHHHHHHHTTHHCTTE.TEEEEEEESS-TTT--B--HHHHHHHHHHHHHT.TEEE CS
  Aminotran_1_2  91 npgdeilvpdptyasyknilrlsggevvryplyseedfhldlealeealkeapegnk.ktkvilvesphNPtGtvatleeleklldlakky.nlll 184
                     +  + l++d+ ++s+ +++  +g  ++++p + e++++++ ++l + l++  e++   + +i ++    ++ +v   +el+++l+ +++  ++++
     EEA19816.1 189 RARLVALSSDQAHSSIAKAALVAGTRFRSVPAKLEDNMEMTGDSLRAVLTKVEEEEGlVPFFITFTLGTTNSCAVDRFAELKAVLNEKESWrRIWV 284
                    55567899*******************************************888776433444444444445555578889999888776558999 PP

                    EEEETTTTCBS CS
  Aminotran_1_2 185 fvDeaYagfvf 195
                     +D aYag ++
     EEA19816.1 285 HIDAAYAGAAL 295
                    99999998766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (529 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       579  (0.032294); expected 358.6 (0.02)
Passed bias filter:                      510  (0.0284455); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.45
# Mc/sec: 3511.66
//
Query:       EEA19817.1  [L=214]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.5e-10   39.1   0.0      3e-09   36.5   0.0    2.1  2  Cupin_2       Cupin domain
     0.0049   16.5   0.0       0.01   15.5   0.0    1.5  1  Cupin_3       Protein of unknown function (DUF861)
  ------ inclusion threshold ------
      0.018   14.9   0.0      0.034   14.0   0.0    1.5  1  AraC_binding  AraC-like ligand binding domain


Domain annotation for each model (and alignments):
>> Cupin_2  Cupin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.1      0.13   7.9e+02      11      23 ..      20      31 ..      15      34 .. 0.74
   2 !   36.5   0.0     5e-13     3e-09       3      71 .]      95     163 ..      93     163 .. 0.91

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.13
                EEEECSSSEEEEE CS
     Cupin_2 11 apshrHpgedeff 23
                +  h+H+ge ++f
  EEA19817.1 20 ITTHNHDGE-AIF 31
                567999998.655 PP

  == domain 2  score: 36.5 bits;  conditional E-value: 5e-13
                 EEEETTEEEEEECSSSEEEEEEEEESEEEEEEC.TEEEEEETTEEEEE-TT-EEEEEE-SSS.-EEEEEEE CS
     Cupin_2   3 velppGesapshrHpgedeffyVleGegeltvd.geeveleaGdsvyfpagtpHrfrNtgde.parllvvy 71 
                 + ++p  ++p+hr      f++VleGe+ l +d g++ +l++Gd v + +gt H frN++d   +rll+v+
  EEA19817.1  95 IDMQPLKETPMHRTVTI-DFGIVLEGEVDLVLDsGQKRTLRQGD-VSIQRGTAHSFRNRSDSrWCRLLFVF 163
                 67899899999998888.*************88799********.699*************9899999886 PP

>> Cupin_3  Protein of unknown function (DUF861)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   1.7e-06      0.01      28      53 ..     113     138 ..     102     144 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1.7e-06
                 EEEEEECEEEEEETTTEEEEEETTEE CS
     Cupin_3  28 fcyileGevkvtpeggetvelraGDl 53 
                 f  +leGev+++ ++g++++lr+GD+
  EEA19817.1 113 FGIVLEGEVDLVLDSGQKRTLRQGDV 138
                 4579*********************8 PP

>> AraC_binding  AraC-like ligand binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   5.8e-06     0.034       7      70 ..      94     157 ..      88     167 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 5.8e-06
                   EETTSTT-SEEEETT-SEEEEEEEEE-EEEEETTEE.EEE-TT-EEEE-TTS-EEEEE-TTSEEE CS
  AraC_binding   7 ieagypdhsfpphvhdeyvihyvteGtgrlrlngrt.ydlgpGdlfLlppgepHdyesdsedgwe 70 
                      + p  ++p h+  +  +++v+eG++ l l+ ++   l++Gd+  +++g+ H+++  s+ +w 
    EEA19817.1  94 VIDMQPLKETPMHRTVTIDFGIVLEGEVDLVLDSGQkRTLRQGDVS-IQRGTAHSFRNRSDSRWC 157
                   5667788999********************9998887*******98.799*******99998886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (214 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       315  (0.0175693); expected 358.6 (0.02)
Passed bias filter:                      240  (0.0133861); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.41
# Mc/sec: 1549.23
//
Query:       EEA19818.1  [L=704]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.7e-07   29.8  13.4    9.6e-07   28.8  13.4    1.5  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
    2.8e-05   23.3   0.1      5e-05   22.5   0.1    1.4  1  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.8  13.4   1.1e-10   9.6e-07       2      33 ..      28      57 ..      27      61 .. 0.94

  Alignments for each domain:
  == domain 1  score: 28.8 bits;  conditional E-value: 1.1e-10
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfy 33
                +C++CrkkK KCd+++  CsnC++++ +C  y
  EEA19818.1 28 SCQSCRKKKLKCDRQQA-CSNCRSRRIPCH-Y 57
                9****************.***********8.5 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5   0.1   5.5e-09     5e-05      24     190 ..     199     371 ..     170     450 .. 0.76

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 5.5e-09
  Fungal_trans  24 t.ssenssksayaspllllailalGalfsesetkesnssltses.qefiafplraeilihedfsspssslwilq.sLlllelyektssdralher.h 116
                   +  s++s   + ++ +ll++ila +++f++  t+  ++++ +++ +e+i   l a++l+  d+   ++ ++ lq sLl +++     +d++   + h
    EEA19818.1 199 KaPSSSSAAVNLNHLALLFSILAAASYFQSLGTNAASAKQVENRcHEYI--TLVAAALTRSDYINYPT-VEGLQaSLLVIQFLPNDGQDTPVRALfH 292
                   245556666888999*******************999999998866666..44445555559999999.*****6677777777777777777779* PP

  Fungal_trans 117 hgvavrlarslgLhrnpsyvgkks..lwklweeeaesrrRlwwaaFylDktialklGrpp...llddsqinlpLPcddd 190
                   +g+ v+ +r++gL +  s  +k       +++ + e  rRl+w + + D ++a   G +    l +   + l +P + +
    EEA19818.1 293 MGTLVNQCRQMGLFQIDSAQNKAFrkAHGYDPVDVELKRRLAWLVSSSDWFLAYLGGPQEgsyLVHPAHMALDMPANIS 371
                   *************998888875448966666666**********98888888876665555444555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (704 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       744  (0.041497); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.42
# Mc/sec: 5022.24
//
Query:       EEA19819.1  [L=438]
Description: MFS monocarboxylate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-30  106.8  74.4    1.4e-26   93.3  47.3    2.0  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.3  47.3   7.8e-31   1.4e-26       5     351 ..      49     391 ..      45     393 .. 0.81
   2 !   27.4  19.2   8.4e-11   1.5e-06      46     166 ..     301     421 ..     299     434 .. 0.78

  Alignments for each domain:
  == domain 1  score: 93.3 bits;  conditional E-value: 7.8e-31
       MFS_1   5 aflsalarsilgpalplalaedlg..ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlgag 100
                 af+s   ++++g++   +++e+l    s s ig++ ++  ++ +++sl++Gr+ d fG+  +l+lg +++++++++++++  +w ++l+  vl G+g  
  EEA19819.1  49 AFCSVGFINAFGVFQA-YYSETLLsnKSNSDIGWIGAINNFFLFAGSLVTGRILDMFGAVVMLWLGSTTTVFSIMMISICKEYWqFILAQGVLLGVGNT 146
                 4444444454444444.55555431157788******************************************555556699**99************* PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllgglla..sslgWravfyilaivsllafvlfllllpeepperkrkspkeeekgtgpaplv 197
                 +l+  ++al+ + f+k + ++a+g+  ag+slG ++ p++  +l+   s+g+ ++  i++++++  ++ f + + +++ ++k +++        +   +
  EEA19819.1 147 LLVCPAIALVGQSFKK-KLAFALGVTIAGSSLGGVIWPVVVHALLqkPSIGFGWTLRIAGLIMIPILI-FSCMFSRPAFASKENRQGGN----DNGTKT 239
                 ****************.*************************99966677799999999999999755.77888888888888877777....333333 PP

       MFS_1 198 p....awkallkdpvlwillialllfffgfsg...lltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaal 289
                 p     w+++ +++     l+++++fff+++g    +++++ y   + g+s   l+ ++++++  ++++++++ g ++d++gr  ++l +   ++ + +
  EEA19819.1 240 PrqtwDWSIVARKQ----TLFTACGFFFIYFGmfmPFFYTTEY-ALTQGFS-SNLSFYTVSIINGASLFGRIIPGMVADKYGR--FNLCIAMTTFSGII 330
                 333566********....6666666655555543366666667.8888888.456666678888888888**********999..77777777777888 PP

       MFS_1 290 glallavtssavllllvlvl.iGfglgfvfpsllalasdlappeeagtasglfntagslggal 351
                 +l+++ vt  +v+++++++l +Gf++g + ++ +a+a++ a+p   gt++g+++   sl+++ 
  EEA19819.1 331 ALCWTTVT--SVAGIVIFALaYGFTSGGILSLQQACAAQIASPTTIGTVVGFIMASTSLSALA 391
                 88888888..88888888888*************************************99876 PP

  == domain 2  score: 27.4 bits;  conditional E-value: 8.4e-11
       MFS_1  46 avaslplGrlsdrfGrrrvlllglllfalglllll.fasslwlllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggl 143
                 +++ ++ G ++d++Gr  + +++ +++++ +l+++ + +s+  ++++ +  G+++g+++++ +a +a++++++  g ++g+++a++sl+a+   ++gg+
  EEA19819.1 301 LFGRIIPGMVADKYGRFNLCIAMTTFSGIIALCWTtV-TSVAGIVIFALAYGFTSGGILSLQQACAAQIASPTTIGTVVGFIMASTSLSALASTPIGGA 398
                 56777779********995555555555552444423.77778******************************************************** PP

       MFS_1 144 lasslgWravfyilaivsllafv 166
                 l++ +g+ ++ +  ++ +l+++ 
  EEA19819.1 399 LIEDYGYLSLSIYSGVSLLFGAS 421
                 **999987766666665555533 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (438 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       635  (0.0354175); expected 358.6 (0.02)
Passed bias filter:                      220  (0.0122706); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.49
# Mc/sec: 2711.50
//
Query:       EEA19820.1  [L=608]
Description: serine peptidase, family S28, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.7e-49  167.7   3.2    1.8e-40  139.1   0.1    2.4  3  Peptidase_S28  Serine carboxypeptidase S28
  ------ inclusion threshold ------
       0.25   11.1   1.2       0.46   10.2   1.2    1.4  1  HipN           Hsp70-interacting protein N N-terminal domain


Domain annotation for each model (and alignments):
>> Peptidase_S28  Serine carboxypeptidase S28
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.1   0.1     2e-44   1.8e-40       7     226 ..      78     311 ..      74     315 .. 0.80
   2 !   28.6   0.5   6.7e-11     6e-07     307     397 ..     438     533 ..     408     542 .. 0.81
   3 ?   -3.4   0.0      0.34     3e+03     400     417 ..     557     574 ..     552     577 .. 0.82

  Alignments for each domain:
  == domain 1  score: 139.1 bits;  conditional E-value: 2e-44
  Peptidase_S28   7 dasnkrtfqqryfvndqfyknggpiflyiGgegslsas.wvsng...eilklAkefgAlvlslEHRfYGqSiPvk....dlstenlrylsseqaLa 94 
                    d++   t+++ry+v+ ++yk ggp+fly  ge s+ +s + + g   ++ ++ +efg+l +  EHR+YG+S P++    d+  en +yl+ +qa+a
     EEA19820.1  78 DNHTIGTYKNRYWVTTKYYKPGGPVFLYDVGESSAYNSaQHMLGeaaFFKEFLEEFGGLGIVWEHRYYGESLPMGpinaDTPAENFKYLTHTQAIA 173
                    6667789*********************88887764441444445878999**********************86332266678************ PP

  Peptidase_S28  95 Dlasfikalk.....qkfklsssskwitfGgSYsgsLaawarkkyPelvvgavaSSaPllakvdfkeylevvetslakvage.cakaveqgfaeve 184
                    D+ +f + ++     ++    + ++wi+ GgSYsg+ aa++r  yP+ +++a aSSaP++a  d + y+e+v + + +++ + ca+  + ++++v+
     EEA19820.1 174 DIPYFAQDFSrpelpSQDLSPKGTPWIMIGGSYSGMRAAFTRDEYPQSIYAAYASSAPVQARADMSAYFEQVYRGMVSNGYHgCAQDLHAAMSYVD 269
                    *******999421112333446789******************************************************9988************8 PP

  Peptidase_S28 185 ell.ktkegrqalkeelqlcskldektdkdvakffsniasefq 226
                    + l + +    ++ ++l l +  + +++ d+    + i+++fq
     EEA19820.1 270 SQLaLDGIPSDDV-KKLFLGEGGEINSNGDFTAALAYIYGTFQ 311
                    6550555566666.44444455555556777777777777766 PP

  == domain 2  score: 28.6 bits;  conditional E-value: 6.7e-11
  Peptidase_S28 307 drqWlyqtCtEfgfyqttds....eaqlfgskvpvelyidlCedvFgasynskkvsqa..vkatnskYGgadnpkatnvvfvnGalDPWhalglkk 396
                    + +W++q C+  gf+q+ +       +l ++  ++ + ++ C   F  ++++ ++  a   +atn++ Gg   ++ +n +++ G++DPW+ l+  +
     EEA19820.1 438 SIAWTWQYCSQWGFFQSDNItpnpTHGLLSTYQSLAYNQEICHRQFPRAAEAGFLPGAptTEATNDDTGG-WLIRPSNTYWSGGEFDPWRTLSPLS 532
                    679*************987665545556666667777789*******9999999966511689*******.9********************9554 PP

  Peptidase_S28 397 s 397
                    +
     EEA19820.1 533 T 533
                    4 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 0.34
  Peptidase_S28 400 ssvvpllikgaahcaDmy 417
                     ++  +++++a hc+D++
     EEA19820.1 557 REIFGYVMQNAMHCFDFN 574
                    5788999********985 PP

>> HipN  Hsp70-interacting protein N N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   1.2   5.1e-05      0.46      28      39 ..     124     135 ..     120     136 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 5.1e-05
        HipN  28 aFFKefleslGa 39 
                 aFFKefle++G+
  EEA19820.1 124 AFFKEFLEEFGG 135
                 8**********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (608 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       285  (0.015896); expected 358.6 (0.02)
Passed bias filter:                      262  (0.0146132); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.42
# Mc/sec: 4323.61
//
Query:       EEA19821.1  [L=512]
Description: chlorohydrolase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-72  245.2   0.0    1.3e-72  245.0   0.0    1.0  1  Amidohydro_1     Amidohydrolase family
    1.7e-11   44.3   0.5      9e-09   35.3   0.0    2.3  2  Amidohydro_3     Amidohydrolase family
  ------ inclusion threshold ------
       0.11   12.7   0.0       0.41   10.8   0.0    2.0  1  tRNA_int_end_N2  tRNA-splicing endonuclease subunit sen54 N-t
       0.18   11.1   0.0       0.28   10.5   0.0    1.3  1  A_deaminase      Adenosine/AMP deaminase


Domain annotation for each model (and alignments):
>> Amidohydro_1  Amidohydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  245.0   0.0   2.9e-76   1.3e-72       2     344 .]     103     508 ..     102     508 .. 0.96

  Alignments for each domain:
  == domain 1  score: 245.0 bits;  conditional E-value: 2.9e-76
                   EEE-EEEEEEECETTECSSS....GHHHHH..................STTHHHHHHHHHHHHHHHHTTEEEEEEEEHSSTHHHHHHHHHHHTSSSE CS
  Amidohydro_1   2 vlPGlIDaHvHleqsllrga....tledwl..................vppetaaealesgiktalksGtttvadmgattstgiealleaaeelplg 76 
                    +PG+ID+H+H++q+++ g+    tl+dwl                  v p +a+ +++++i+++l++Gttt+ ++ +++++++++l+  + +   g
    EEA19821.1 103 FFPGFIDTHIHASQYPNAGIfgssTLLDWLkkytfpmeksfgaigegkVAPPQAYTVYNKVISRTLSHGTTTASYFATVHVPATNLLAALCYRR--G 197
                   58**********************************************88888************************************88887..* PP

                   EEEEEESSEGGS..........GCCCSHHHHHHHHHHHHHHHHHHCTTTCEEEEEEECGTCCSHHHHHHHHHHHHHHH..TTEEEEEETSSCHHHHH CS
  Amidohydro_1  77 lrilggkvsldr..........gsaetskasreklkagaaetikgkadgvvkvalapheapafsdeelkealkeakkr..dlpvaiHaletkgeved 161
                   +r+++g+v++d+           s e s   ++++++++    +++++++v ++++p++ap++s+e+l  + k+a+ +   l++++H++e+k+ev  
    EEA19821.1 198 QRAFVGRVCMDNlvfcpedyhdASSEESVSATKEVIEYI--HALDPEGKLVAPIVTPRFAPTCSNEALCGLGKLAASYtpPLHIQTHISENKNEVLL 292
                   *********************977788888999999998..8889*********************************8889999999********* PP

                   HHHHHTTTEEEETTTTSTCCHHTTTHCCEEEHCTCEEEHHHHHHHHHHHHHHCEEHHHHHHHHSEHHHHHHHHHHHHTSCEEEEEECTTSSCCGGHH CS
  Amidohydro_1 162 aeaafgetiehgthlevaeslglldeiklilahgvhltpteaellkerlkeagvahcpfsnsilrsgrealrkaldeGvkvglgtDgaasgnslnll 258
                   +++ f+   e++++ +v+e+ +ll++ ++ilah vhltp+e++l+k+r  +a+++hcp+sns l+sg +++r ++deG+ vglgtD ++ g s+++l
    EEA19821.1 293 VKELFQ---ESEGYAHVYEESALLTP-RTILAHAVHLTPEEMALVKAR--DAKISHCPASNSALGSGHCPVRTLMDEGITVGLGTD-VSGGYSPSIL 382
                   ******...*****************.*********************..************************************.********** PP

                   HHHHHHHHHHHHCCTT....TTHCHCHHHHHHHHHTHHHHHHTT-TTTSSSS-TTSB--EEEECCCT.............................. CS
  Amidohydro_1 259 eelrlalklqrgllye....deegglslkealrmaTingAkalglddkvGsievGkdADlvvvdldi.............................. 321
                   e+ r+a++++r++  +     ++  ls++eal++aT +gA+++ ++d++G +e+G ++D+ +++l +                              
    EEA19821.1 383 ESSRQACLVSRLVSSQadvtTGRETLSVEEALYLATRGGAQVVDMADQIGGFEKGMYFDAQLIELGPvvesvsseadcegvteeakedmgnvdvfgw 479
                   *************999988877888****************************************5556778899999******************* PP

                   ......CGGGTTTCTSEEEEEEEETTEEE CS
  Amidohydro_1 322 ......laafvglkkdgnvkkvivkGklv 344
                         +a++v + +d+nv+ v+v+G+lv
    EEA19821.1 480 enweekIAKWVWNGDDRNVRAVWVSGRLV 508
                   **************************997 PP

>> Amidohydro_3  Amidohydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.1   0.1   0.00069       3.1       8      21 ..     101     114 ..      99     123 .. 0.81
   2 !   35.3   0.0     2e-12     9e-09     311     472 ..     319     508 ..     299     509 .. 0.76

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.00069
  Amidohydro_3   8 rlvlPGFvDsHtHl 21 
                   ++ +PGF+D H+H 
    EEA19821.1 101 GFFFPGFIDTHIHA 114
                   6678*********3 PP

  == domain 2  score: 35.3 bits;  conditional E-value: 2e-12
  Amidohydro_3 311 lehaegvtesqiervaalqvaagvqpvfnfedelldsrlgperargstpvkellnagvkvalgsD..apvgpfdpwprigaavmrktrrgg.evlrp 404
                   l+ha  +t+++++ v+a  + ++ +p++n            + ++g+ pv++l++ g++v lg+D     +p    ++ +a++ ++ ++ + +v++ 
    EEA19821.1 319 LAHAVHLTPEEMALVKARDAKISHCPASNS-----------ALGSGHCPVRTLMDEGITVGLGTDvsGGYSPSILESSRQACLVSRLVSSQaDVTTG 404
                   566666789999999999999999999988...........6677889*****************644444444445668999999999999***** PP

  Amidohydro_3 405 deelsleealalyTrgpAkalgledrkGtLevGadADlvvld...........adpldvdppelaear............................. 461
                   +e ls+eeal l Trg+A+++ + d  G+ e+G++ D  +++           ad            +                             
    EEA19821.1 405 RETLSVEEALYLATRGGAQVVDMADQIGGFEKGMYFDAQLIElgpvvesvsseADCEG---------Vteeakedmgnvdvfgwenweekiakwvwn 492
                   *********************************9877777775544444443333333.........133444445677888888888888888888 PP

  Amidohydro_3 462 .....vrltvvdGrvv 472
                        vr+++v+Gr v
    EEA19821.1 493 gddrnVRAVWVSGRLV 508
                   8888888888888877 PP

>> tRNA_int_end_N2  tRNA-splicing endonuclease subunit sen54 N-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   9.3e-05      0.41      48      69 ..     402     423 ..     375     425 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 9.3e-05
  tRNA_int_end_N2  48 rrgrlwLlpeEaLYLvErGsld 69 
                      + gr  L  eEaLYL+ rG  +
       EEA19821.1 402 TTGRETLSVEEALYLATRGGAQ 423
                      78999*************9655 PP

>> A_deaminase  Adenosine/AMP deaminase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   6.2e-05      0.28     219     277 ..     320     372 ..     299     388 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 6.2e-05
                  CE-GGGGGSHHHHHHHHHCT-EEEE-HHHHCCCSST-TTTT-CHHHHHHTT-EEEE--B CS
  A_deaminase 219 gHGvrlrkdpvLqyllalaqiplevcPlSNvalgafleyaenPlkeflerglnvslntD 277
                  +H v+l   p+ ++l   +  ++  cP+SN al       + P+++++++g+ v l+tD
   EEA19821.1 320 AHAVHLT--PEEMALVKARDAKISHCPASNSAL----GSGHCPVRTLMDEGITVGLGTD 372
                  5555554..333566777788899*********....77899****************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (512 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       433  (0.0241508); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 3486.37
//
Query:       EEA19822.1  [L=1073]
Description: glycine dehydrogenase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.3e-174  581.1   0.0   4.4e-162  539.8   0.0    2.6  2  GDC-P            Glycine cleavage system P-protein
    6.1e-08   32.3   0.5    2.4e-07   30.3   0.2    2.0  2  Beta_elim_lyase  Beta-eliminating lyase
     0.0053   15.3   0.1       0.16   10.4   0.0    2.1  2  Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
     0.0085   15.4   0.3      0.024   14.0   0.1    1.7  2  DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family


Domain annotation for each model (and alignments):
>> GDC-P  Glycine cleavage system P-protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  539.8   0.0  9.9e-166  4.4e-162       1     430 []      86     551 ..      86     551 .. 0.92
   2 !   38.5   0.0   1.4e-13   6.2e-10      31     283 ..     571     842 ..     562     846 .. 0.71

  Alignments for each domain:
  == domain 1  score: 539.8 bits;  conditional E-value: 9.9e-166
                 HHH-SS-HHHHHHHHHHHT..-SSHHHHHHHHS-GGGB--S-------..................--HHHHHHHHHHHHTTB--.-EE--BTTB---- CS
       GDC-P   1 erhigpsekdqkemLetlG..lkslddliekavPkeiklkkelkleap..................ksEeellaelekiasknkv.vksfiGaGyydti 78 
                 +rhigps  + kemL+tl   ++sld+++++ +P++i  kk+l ++ p                    E+++l+ l++  ++  +  ksfiG Gyy ti
  EEA19822.1  86 RRHIGPSPDAAKEMLATLSppAASLDEFVKQVLPADILSKKDLVITPPkvsaateetlyrdpvdggLGESDMLKLLDEYRKNISMaGKSFIGGGYYPTI 184
                 69****************75589*******************9999999*****************************7665555689*********** PP

                 --HHHHHHTTT-HHHHS--S-SSGGG-HHHHHHHHHHHHHHHHHHT-SEE-S-BS-HHHHHHHHHHHH.....HHH-SSS--EEEEETTS-HHHHHHHH CS
       GDC-P  79 lPaviqrnilenpewytaYtPYqaEisqGrLeallnfqtlvadltGldianasllDegtAaaEAvlla.....araskkkakkvvvdkkvhpqtlevlk 172
                 +P+vi+rnilenp+wyt+YtPYq+EisqGrLe+llnfqtl++dltGl++anas+lDegtAaaEA++++     ++++kk  k +vv++ +h+qt +v++
  EEA19822.1 185 VPPVILRNILENPAWYTSYTPYQPEISQGRLESLLNFQTLTTDLTGLPVANASVLDEGTAAAEAMTMSlatapMAKQKKAGKSFVVSHLCHEQTVAVMR 283
                 *******************************************************************8222223345666899**************** PP

                 HHHGGGT-EEEEE-GGG--S-......S-EEEEEEEES-TTSB----HHHHHHHHHTT-EEEEEE-TTGGGTB--HHHHT-SEEEEE-TTTT---GGG- CS
       GDC-P 173 trakglgieivevdlteekvtd...kekevagvlvqypnteGriedlkelvekakkkkslvvvaadllaLtllkpPgelgaDivvGsaqrfGvPlgyGG 268
                  ra+g+gi++v+ d+ +++++    + +++ gvl qyp+teG + d+++l +++++   +++va+dllaLt+lk+Pge+gaDi++Gsaqr+GvP+g+GG
  EEA19822.1 284 SRAEGFGINLVIGDILADDAKLvkeQGDNLIGVLAQYPDTEGGVLDFESLGKTVHELGGTFSVATDLLALTVLKAPGEFGADIAFGSAQRLGVPMGFGG 382
                 *************9987765543337789********************************************************************** PP

                 ---EEEEE-GGGGGG--S-EEEEEEBTTS-EEEEEE-CCGSHHCCHHHCS-S--S--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT.. CS
       GDC-P 269 PhagffAvkeklkRkiPGRlvGvskDaegkralrlalqtREqHirRdkAtsniCtaqaLlAnlaalyavyhGkeglkeiarrihkkteilakelkkk.l 366
                 Pha+ffA+++k+kRk+PGRl+GvskD+ g+ralrlalqtREqHirR+kAtsniCtaqaLlAn++a+ya+yhG++glk ia+ri++ t++l+++l     
  EEA19822.1 383 PHAAFFATTDKYKRKMPGRLIGVSKDRLGNRALRLALQTREQHIRREKATSNICTAQALLANMSAMYAIYHGPQGLKVIAQRIMAMTALLREKLLGLgY 481
                 ********************************************************************************************9977644 PP

                 T-EE.....--SSBSSEEEEE--T.TTHHHHHHHHHHTTEE-EEESTTEEEEE--TT--HHHHHHHHHHH CS
       GDC-P 367 eeel.....kkkkffdtllievee.kaaekvlkkaekeglnlrkvelktvgialdEtvtkedieallkvl 430
                 +  +     ++  +fdtl++e+ + ++ae +l+ a+++++ +r+v  ++++++ldEtv k++++++l+v+
  EEA19822.1 482 NVPVrsntgDEGVLFDTLTVELPDsASAESLLAAAKSAKIYFRQVGPNKIALSLDETVGKSELRQILQVF 551
                 44441111134579**********677777**************************************97 PP

  == domain 2  score: 38.5 bits;  conditional E-value: 1.4e-13
                 S-GGGB--S-------.....--HHHHHHHHHHHHTTB--.-EE--BTTB------HHHHHHTTT-HHHHS--S-SS.GGG-HHHHHHHHHHHHHHHHH CS
       GDC-P  31 vPkeiklkkelkleap.....ksEeellaelekiasknkv.vksfiGaGyydtilPaviqrnilenpewytaYtPYq.aEisqGrLeallnfqtlvadl 122
                 vP+++  +++  l++p     +sE+++l+ ++++ sk+   ++s+i  G   ++l a+ +   ++ pe+  +  P+  a++ +G  + + +  + +ad+
  EEA19822.1 571 VPASL-ERTSAYLTHPvfntyHSETDMLRYIHHLESKDLSlAHSMIPLGSCTMKLNATTEMIPISWPEFS-QIHPFMpADAVKGYTQMIDDVEQQLADI 667
                 66666.34444455555666699**************998899**************9999889999985.55666516899***************** PP

                 HT-SEE-S-BS-HHHHHHHHHHH..HHHH-S....SS--EEEEETTS-HHHHHHHHHHHGGGT-EEEEE-GGG-.-S-.............S-EEEEEE CS
       GDC-P 123 tGldianasllDegtAaaEAvll..aarask....kkakkvvvdkkvhpqtlevlktrakglgieivevdltee.kvtd..........kekevagvlv 204
                 tG+  a+  +  ++ A +E + l  +++ +     ++++  ++  + h  +       a   g+++v+ ++ ++ +  d          +++++a++++
  EEA19822.1 668 TGM--AEVTVQPNSGAQGEFAGLrlIKKYQEsvsgGNRNICLIPVSAHGTNP----ASAAMAGFKVVTIKCDTKtGNLDiedlkakcekHKDDLAAIMI 760
                 **7..78888899999999766611222222111123344444444333221....2222333333333221110111134455555557889****** PP

                 EES-TTSB---.-HHHHHHHHHTT-EEEEE.E-TTGGGTB--HHHHT-SEE.EEE-TTTT---GGG----EEEEE-GGGGGG CS
       GDC-P 205 qypnteGried.lkelvekakkkkslvvva.adllaLtllkpPgelgaDiv.vGsaqrfGvPlgyGGPhagffAvkeklkRk 283
                  yp+t+G  e+ +ke+ + ++k+   v +  a++ a   l +Pge+gaD+  +   + f +P g GGP +g + v+e+l   
  EEA19822.1 761 TYPSTFGVFEPgVKEVCDIVHKHGGQVYMDgANMNAQIGLCSPGEIGADVChLNLHKTFCIPHGGGGPGVGPIGVAEHLRPF 842
                 **********999***********999987155556666***********84667889*************99999887655 PP

>> Beta_elim_lyase  Beta-eliminating lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0      0.28   1.3e+03      98     135 ..     317     355 ..     240     357 .. 0.68
   2 !   30.3   0.2   5.4e-11   2.4e-07      24     206 ..     647     825 ..     639     826 .. 0.75

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.28
                      EEEE-EBTTTBE-HHHHHHHS--S-T.TS-EEEEEEEES CS
  Beta_elim_lyase  98 lrdlknkeaGkmdlekleaaikevga.heekiklisltv 135
                      l + +  e G +d+e+l + ++e g  ++  + l+ ltv
       EEA19822.1 317 LAQYPDTEGGVLDFESLGKTVHELGGtFSVATDLLALTV 355
                      333344444999999999999999888999888888886 PP

  == domain 2  score: 30.3 bits;  conditional E-value: 5.4e-11
                      --CCCT--HHHHHHHHHHHHHTT-SEEEEES.-HHHHHHHHHHHH--TTEEEEEETT.........-HHHHSSTTHHHHCC--EEEEE-EBTT. CS
  Beta_elim_lyase  24 GdesYgedktvnrLedavaelfgkeaalfvp.qGtaAnsillkillqrgeevivtep.........ahihfdetgaiaelagvklrdlknkea. 106
                       d++ g  + + ++e+++a+++g++ +   p +G +++   l+++ ++++e + + +         ah+   ++ a a++ag k++++k + + 
       EEA19822.1 647 ADAVKGYTQMIDDVEQQLADITGMAEVTVQPnSGAQGEFAGLRLI-KKYQESVSGGNrniclipvsAHG---TNPASAAMAGFKVVTIKCDTKt 736
                      578889999999***********9988776637999998777655.57777777777244443333333...3355566777777777755555 PP

                      TBE-HHHHHHHS--S-TTS-EEEEEEEESSBTTTTTB---HHHHHHHHHHHHHCT-EEEEEETTHHHHHHHHTS-CHHHHTTSSEEEEESSSTT CS
  Beta_elim_lyase 107 GkmdlekleaaikevgaheekiklisltvTnntagGqvvsleelrevaaiakkygiplhlDgARfanaakslgeivkemfsyvDsvtmslkKdl 200
                      G++d+e+l+a+ ++   h+++ ++i++t       G  v    ++ev +i++k+g ++ +DgA +  +a+   +++ e+  ++D++ + l K  
       EEA19822.1 737 GNLDIEDLKAKCEK---HKDDLAAIMITYPSTF--G--VFEPGVKEVCDIVHKHGGQVYMDGANM--NAQIGLCSPGEI--GADVCHLNLHKTF 819
                      **************...999********99997..5..55668********************65..555666777777..4677777777777 PP

                      --SS-E CS
  Beta_elim_lyase 201 lanvGg 206
                      +++ Gg
       EEA19822.1 820 CIPHGG 825
                      777665 PP

>> Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.4   0.0   3.6e-05      0.16      73     196 ..     239     371 ..     220     374 .. 0.78
   2 !    2.6   0.0    0.0089        40     112     192 ..     729     811 ..     708     817 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 3.6e-05
                      ESSHHHHHHHHHHTTS........-TTEEEEEESTSSHHHHHHHHHTHHHTTCEEEEEST.TSHHHHHHHCCTTEEEEEEESS-TTTT----HH CS
  Cys_Met_Meta_PP  73 vssGmaAiaaailall........kaGdeivvsddlYggtqrllkkvlkklgievkfvdt.sdleelekaikentklvylEtptnpllkvvDie 157
                      +  G+aA +a+ ++l+        kaG+  vvs+ +++ t +++++ ++ +gi+  + d  +d ++l k   +n   v+   p +    v+D+e
       EEA19822.1 239 LDEGTAAAEAMTMSLAtapmakqkKAGKSFVVSHLCHEQTVAVMRSRAEGFGINLVIGDIlADDAKLVKEQGDNLIGVLAQYP-DTEGGVLDFE 331
                      44555555555555542222222267999*****************************9856777888888888888888877.56789***** PP

                      HHHHHHHHTT.-EEEEEGTTTHTTTS-GGGGT-SEEEEET CS
  Cys_Met_Meta_PP 158 kiaklakkag.vlvvvDntfaspllqrplklgaDivvhSa 196
                      ++ k++++ g +  v    +a  +l  p ++gaDi   Sa
       EEA19822.1 332 SLGKTVHELGgTFSVATDLLALTVLKAPGEFGADIAFGSA 371
                      *********97777777788888************99997 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.0089
                      HHHTTCEEEEESTTSHHHHHHHCCTTEEEEEEESS-TTTT----HHHHHHHHHHTT-EEEEEGTTTHT..TTS-GGGGT-SEE CS
  Cys_Met_Meta_PP 112 lkklgievkfvdtsdleelekaikentklvylEtptnpllkvvDiekiaklakkagvlvvvDntfasp..llqrplklgaDiv 192
                      + k   ++   d +dl++  ++ k+   ++ +  p+   +  + +++++++++k+g  v +D + +     l+ p + gaD+ 
       EEA19822.1 729 TIKCDTKTGNLDIEDLKAKCEKHKDDLAAIMITYPSTFGVFEPGVKEVCDIVHKHGGQVYMDGANMNAqiGLCSPGEIGADVC 811
                      45555555566666666666666778888888889998899999******************98776656799********96 PP

>> DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       0.4   1.8e+03     240     306 ..     460     525 ..     408     533 .. 0.71
   2 !   14.0   0.1   5.3e-06     0.024      25     146 ..     657     792 ..     645     826 .. 0.87

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.4
                      HHHHH.HHHHHHHHHHHHTCCCCEESCGGTTSSSEEESCEEEEEHCCHHHCHHHHHHHHHHCCEE-B- CS
  DegT_DnrJ_EryC1 240 lvarR.reiaelykeeLaelegtaelttpketkkhawhlyavlveeeaevkrdelvealkeegigtrv 306
                      ++a+R  ++++l++e+L +l+++++++ ++ ++   +  ++v ++++  ++ + l++a k+++i +r 
       EEA19822.1 460 VIAQRiMAMTALLREKLLGLGYNVPVRSNTGDEGVLFDTLTVELPDS--ASAESLLAAAKSAKIYFRQ 525
                      44444145678899999999999999888888867777788888877..5788999999999887765 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 5.3e-06
                      HHHHHHHHHHHHT.-SEEEEESSHHHHHHHHHHH.......TTTT..TT-EEEEESSS-THHHHHHHHTT-EEEEE-B-TTTSSB-GGGCGGG- CS
  DegT_DnrJ_EryC1  25 veeFEkafaaylg.vkhaiavssGtaAlhlaLra.......lgvg..pgdeVIvpsltFvatanavlelgakpvfvDvdpdtynidpaaieaai 108
                      +++ E+++a+ +g ++  +  +sG ++   +Lr        +  +  +++ +++p     +  ++++ +g k+v +  d +t n+d ++++a+ 
       EEA19822.1 657 IDDVEQQLADITGmAEVTVQPNSGAQGEFAGLRLikkyqesV--SggNRNICLIPVSAHGTNPASAAMAGFKVVTIKCDTKTGNLDIEDLKAKC 748
                      67889********77888999***********9966655333..244788899999888888899999************************** PP

                      -TTE...EEEEEB..-GGGB--.-HHHHHHHHHHCT-EEEEE-T CS
  DegT_DnrJ_EryC1 109 tert...kaIlpV..hlyGqva.dmdalkaiaakhglkvieDaA 146
                      ++     +aI++    ++G +   ++++ +i +khg  v  D A
       EEA19822.1 749 EKHKddlAAIMITypSTFGVFEpGVKEVCDIVHKHGGQVYMDGA 792
                      **99999999987557999999899**********999999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1073 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       478  (0.0266607); expected 358.6 (0.02)
Passed bias filter:                      448  (0.0249875); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.80u 0.33s 00:00:01.13 Elapsed: 00:00:00.48
# Mc/sec: 6722.06
//
Query:       EEA19823.1  [L=569]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-20   71.9   2.1    4.3e-20   71.9   2.1    1.9  2  MFS_1     Major Facilitator Superfamily
    6.1e-12   45.1   1.1    3.7e-10   39.3   0.0    3.1  3  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.9   2.1   4.8e-24   4.3e-20      31     345 ..     114     493 ..      64     499 .. 0.75
   2 ?   -1.7   0.0      0.12   1.1e+03     160     187 ..     522     551 ..     515     559 .. 0.54

  Alignments for each domain:
  == domain 1  score: 71.9 bits;  conditional E-value: 4.8e-24
       MFS_1  31 pseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa..sslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigll 126
                 + +++l +t+ +++a v++lp+G + drfG+r + ++g l++++g+ll+ fa  ++ +   +++ ++ +lg+ ++f  +   ia  fpk + g  ++l+
  EEA19823.1 114 ELQLNLFFTVASITANVSALPIGTMLDRFGPRICNIIGCLCLVIGSLLMYFAfnIPEFdGYVIGNLFLSLGGTCIFVPA-FQIANAFPK-KSGVIVALI 210
                 567999***************************************7777788553334459999999999965555444.457888999.999999999 PP

       MFS_1 127 sagfslGailgpllggllasslg..Wravfyilaivsllafv.lfllllpeepperkrkspkeee.................................. 188
                 +++f ++a++  l+  + ++  +   r  +++l+ +s+ +f+ l  ++l+ ++p +  +  +e+                                   
  EEA19823.1 211 TGAFDASAAVF-LFYRIAYETTNraIRPEYFFLGYLSVPLFIfLEQMFLLPTKPYKTVFQLEEKIeaardpsrdihesdeeisddnevasiraarrkkr 308
                 99999999777.66666665555669999***********99544445544444444444444447888888888899999999999999999999999 PP

       MFS_1 189 .....................kgtgpaplvp.awkallkdpvl......willialllfffgfsg..lltllplylqevlgls...........gllla 246
                                      ++ ++++++  +w+ l+  pv       w++li+ll+   ++++  + +++ ++ + ++ +            +l+ +
  EEA19823.1 309 qnklknidkvlgglderqqreEQEEERHATArVWGVLHGEPVQkqfmspWFILITLLT---VLQMlrMNYFIATI-RAQYEYMldseaqaeninNLFDV 403
                 999999999999999988888444444444467********77665455544444444...55555777777775.66666666788998888888888 PP

       MFS_1 247 glllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfntag 345
                 +  l+++++++    +++g l+d+l+   +l+l+++l++++ ++ +l  v     ++++ +vl+ +   ++++++  +a+++++ +  g+++g++  ++
  EEA19823.1 404 A--LPIGGVIS---TPFIGLLLDHLSVPSTLTLIVFLTTAVGVLNCLPYVW----AGYVTVVLFVLLRPLYYSAMSDYATKVFGFSTFGRVYGAIICIS 493
                 8..88888888...9*********999666666666666666666666665....55556666667899999999999999999888899888886555 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.12
       MFS_1 160 vsllafv..lfllllpeepperkrkspkee 187
                 + +l+f+   +l+++++ +++r+  +++e 
  EEA19823.1 522 LVVLSFIigTILVVFVQVESRRWLAAETEA 551
                 333333322122666666666666666655 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.3   0.0   4.1e-14   3.7e-10      43     246 ..     102     319 ..      60     329 .. 0.69
   2 ?    0.4   0.1     0.026   2.3e+02      19      95 ..     373     445 ..     358     461 .. 0.80
   3 !    1.9   0.0    0.0087        78     173     210 ..     522     556 ..     512     568 .. 0.66

  Alignments for each domain:
  == domain 1  score: 39.3 bits;  conditional E-value: 4.1e-14
                 H.............HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS CS
    Sugar_tr  43 e..........ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiA 131
                 e          +++++ l++ ++++ a +++l +g++ drfG + + +i+++++vig++l+++a +  ++  +++g +++  ++G+++++vP ++  +A
  EEA19823.1 102 EledgvdvcfkQELQLNLFFTVASITANVSALPIGTMLDRFGPRICNIIGCLCLVIGSLLMYFAFNIPEFDGYVIGNLFL--SLGGTCIFVPAFQIANA 198
                 24455555555789999************************************************99**********995..789************** PP

                 -SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHH.HHHCCHHHHHHHHHHGGGS---HHHHHHTT-HH..HHHHHHHHHHHC...HHHHHHH CS
    Sugar_tr 132 pkklRgalvslyqlaitfGilvaaifglglnktsnadgwri.llglqlvpallllilllflPESPrylvekgkee..eakevlaklrge...edadrel 224
                  +k+ g +v l   a  +   v  +   ++++t+ a +  + +lg  +vp  ++l  +++lP  P+ +v + +e+  +a+   +++ ++     +d e+
  EEA19823.1 199 FPKKSGVIVALITGAFDASAAVFLFYRIAYETTNRAIRPEYfFLGYLSVPLFIFLEQMFLLPTKPYKTVFQLEEKieAARDPSRDIHESdeeISDDNEV 297
                 ********9886655554444433333333444443333330344444444455556788886666666555544415555444444442224556666 PP

                 HHHHHHHHHHHH.....HTTHH CS
    Sugar_tr 225 aeekdsleaeqeeekaswkell 246
                 a + ++ +++++++ + ++++l
  EEA19823.1 298 ASIRAARRKKRQNKLKNIDKVL 319
                 6666666666555555555555 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.026
                 GGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH- CS
    Sugar_tr  19 igafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaa 95 
                 +++f++ + +++++ l+++ ++++       l+  ++ +G++i+  f+gll d ++  ++l  +++l+ + +vl+ +
  EEA19823.1 373 MNYFIATIRAQYEYMLDSEAQAEN----INNLFDVALPIGGVISTPFIGLLLDHLSVPSTLTLIVFLTTAVGVLNCL 445
                 778888888788887777776555....5778888999999999999999999999999999999998888887765 PP

  == domain 3  score: 1.9 bits;  conditional E-value: 0.0087
                 HHHCCHHHHHHHHHHGGGS---HHHHHHTT-HHHHHHH CS
    Sugar_tr 173 llglqlvpallllilllflPESPrylvekgkeeeakev 210
                 l+ l++++    ++++++  ES r+l   ++ e+ +  
  EEA19823.1 522 LVVLSFIIG--TILVVFVQVESRRWLAAETEAEQQR-L 556
                 555666666..3444455559******999777654.3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (569 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1061  (0.0591779); expected 358.6 (0.02)
Passed bias filter:                      554  (0.0308997); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.31s 00:00:00.96 Elapsed: 00:00:00.43
# Mc/sec: 3969.01
//
Query:       EEA19824.1  [L=156]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.9e-20   71.4   0.0    1.1e-19   71.0   0.0    1.2  1  Methyltransf_25  Methyltransferase domain
    1.9e-16   60.2   0.0    2.5e-16   59.8   0.0    1.1  1  Methyltransf_31  Methyltransferase domain
    5.5e-15   55.8   0.0    8.1e-15   55.2   0.0    1.2  1  Methyltransf_11  Methyltransferase domain
    2.3e-11   43.8   0.0    2.8e-11   43.5   0.0    1.1  1  Methyltransf_23  Methyltransferase domain
    1.3e-09   38.7   0.0    1.9e-09   38.1   0.0    1.3  1  Methyltransf_12  Methyltransferase domain
    2.5e-08   33.5   0.0    3.1e-08   33.3   0.0    1.1  1  Ubie_methyltran  ubiE/COQ5 methyltransferase family
    6.9e-07   29.2   0.0    8.2e-07   29.0   0.0    1.1  1  PCMT             Protein-L-isoaspartate(D-aspartate) O-methyl
    7.4e-07   28.9   0.0    9.2e-07   28.6   0.0    1.1  1  MTS              Methyltransferase small domain
    4.7e-06   26.1   0.0    4.9e-06   26.0   0.0    1.1  1  CMAS             Mycolic acid cyclopropane synthetase
    0.00031   20.7   0.0    0.00043   20.2   0.0    1.2  1  Methyltransf_18  Methyltransferase domain
    0.00064   19.8   0.0    0.00078   19.5   0.0    1.1  1  Methyltransf_32  Methyltransferase domain
     0.0028   17.1   0.0     0.0031   17.0   0.0    1.1  1  PrmA             Ribosomal protein L11 methyltransferase (Prm
     0.0042   16.6   0.0     0.0052   16.3   0.0    1.2  1  Methyltransf_4   Putative methyltransferase
     0.0073   16.0   0.0       0.15   11.7   0.0    2.0  1  UPF0020          Putative RNA methylase family UPF0020
     0.0096   15.0   0.0      0.013   14.6   0.0    1.1  1  RrnaAD           Ribosomal RNA adenine dimethylase
     0.0097   16.0   0.0      0.012   15.8   0.0    1.1  1  FtsJ             FtsJ-like methyltransferase
  ------ inclusion threshold ------
      0.019   14.6   0.0      0.026   14.2   0.0    1.1  1  Methyltr_RsmB-F  16S rRNA methyltransferase RsmB/F
      0.054   13.6   0.3        3.4    7.8   0.0    2.4  2  SepRS_C          O-phosphoseryl-tRNA synthetase C-terminal do
      0.062   12.9   0.1      0.088   12.4   0.1    1.4  1  MetW             Methionine biosynthesis protein MetW
      0.068   12.8   0.0      0.078   12.6   0.0    1.1  1  TPMT             Thiopurine S-methyltransferase (TPMT)
       0.09   12.3   0.0       0.14   11.7   0.0    1.3  1  Methyltransf_15  RNA cap guanine-N2 methyltransferase
       0.16   10.8   0.0        0.2   10.6   0.0    1.3  1  Methyltransf_9   Protein of unknown function (DUF1698)
       0.22   11.0   0.0        3.6    7.0   0.0    2.3  2  CheR             CheR methyltransferase, SAM binding domain


Domain annotation for each model (and alignments):
>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.0   0.0   1.4e-22   1.1e-19       1      86 [.      44     135 ..      44     139 .. 0.93

  Alignments for each domain:
  == domain 1  score: 71.0 bits;  conditional E-value: 1.4e-22
                      EEEET-TTSHHHHHHHCTS.TSSEEEEEESSHHHHHHHHHHHHHTTT......TEEEEESBCCGBSSSTTTEEEEEEESTGGGSSHHHHHHHH CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrl.gkakvtgvDiseemleaareraeeegl......nvefvqgdaedlpfedgsfDlvvssgalhhlsdedlekal 86 
                      +Ld+GcG+G++t  +ak + g ++v+g+Dis e l++a+e a+e+++      +v f+qg++  lp++ ++fD+v+ss+++ h++++dl+++l
       EEA19824.1  44 ILDVGCGPGTITTGFAKYVsG-GSVVGIDISTEVLQNAKESAAEANVptegpgSVVFEQGNILGLPYHGDTFDIVYSSQVFGHFPPPDLPELL 135
                      8******************55.********************9966667777*************************988********99987 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.8   0.0   3.2e-19   2.5e-16       2      91 ..      39     130 ..      38     136 .. 0.87

  Alignments for each domain:
  == domain 1  score: 59.8 bits;  conditional E-value: 3.2e-19
  Methyltransf_31   2 dkglrvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielArenaqklgld.....nveFeqgdieeleklledekfDlilsnevlnaladp 90 
                      +kg r+lD+GCG G++t  +a +  +++ vvGiDis e+++ A+e a++ ++       v Feqg+i  l+  ++ ++fD++ s +v+ +++ p
       EEA19824.1  39 EKGDRILDVGCGPGTITTGFA-KYVSGGSVVGIDISTEVLQNAKESAAEANVPtegpgSVVFEQGNILGLP--YHGDTFDIVYSSQVFGHFPPP 129
                      7999*****************.77899******************6655544334444*************..99************9998876 PP

  Methyltransf_31  91 d 91 
                      d
       EEA19824.1 130 D 130
                      5 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.2   0.0     1e-17   8.1e-15       1      81 [.      45     135 ..      45     138 .. 0.93

  Alignments for each domain:
  == domain 1  score: 55.2 bits;  conditional E-value: 1e-17
                      EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-......EEEETTEECCCTSS-TT-EEEEEEES-CCC-..CCHHHHH CS
  Methyltransf_11   1 LdvGcGtGrlaealakrg..arvvgvDlskemlklakekaseegl......kvefvvadaeklpfednsfDlvvssevlhhv..edpekal 81 
                      LdvGcG G ++  +ak++  ++vvg+D+s+e+l+ ake a e+++      +v f ++++  lp+  ++fD+v+ss+v+ h+  +d+ ++l
       EEA19824.1  45 LDVGCGPGTITTGFAKYVsgGSVVGIDISTEVLQNAKESAAEANVptegpgSVVFEQGNILGLPYHGDTFDIVYSSQVFGHFppPDLPELL 135
                      8**************99999****************99999999999999*99*****************************776666665 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.5   0.0   3.6e-14   2.8e-11       4     102 ..      22     135 ..      19     148 .. 0.74

  Alignments for each domain:
  == domain 1  score: 43.5 bits;  conditional E-value: 3.6e-14
  Methyltransf_23   4 qreeelsdklerllpklraggrvLdiGcGtGillevlrengf..svtgvDlspeaveiaekakkaqkdqfdeqeaaepqg.............. 81 
                      q+ + +    ++llp  ++g r+Ld+GcG G+ +  +++++   sv+g+D+s e  + a       k+++   ea +p +              
       EEA19824.1  22 QQSRTAESYAAFLLPHIEKGDRILDVGCGPGTITTGFAKYVSggSVVGIDISTEVLQNA-------KESA--AEANVPTEgpgsvvfeqgnilg 106
                      55666667778899999**************9999999997777********8633333.......3333..3333333344455555556666 PP

  Methyltransf_23  82 ......kfdlIvlrevlehvp..dppell 102
                            +fd++++++v++h+p  d+pell
       EEA19824.1 107 lpyhgdTFDIVYSSQVFGHFPppDLPELL 135
                      666667***************66678877 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.1   0.0   2.5e-12   1.9e-09       1      86 [.      45     135 ..      45     139 .. 0.75

  Alignments for each domain:
  == domain 1  score: 38.1 bits;  conditional E-value: 2.5e-12
  Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakre..nnnnnnvelealdlldldgg.ssfDlvvasnvlhhl..kdirevl 86 
                      L++GcG G+++  ++++ ++ +++g+Dis++++++ake  a+ +   +    v +e+ ++l l+   ++fD+v++s+v+ h+  +d+ e+l
       EEA19824.1  45 LDVGCGPGTITTGFAKYVSGGSVVGIDISTEVLQNAKESAAEANvpTEGPGSVVFEQGNILGLPYHgDTFDIVYSSQVFGHFppPDLPELL 135
                      8********************************5555554443311334445566666655444449***************766666665 PP

>> Ubie_methyltran  ubiE/COQ5 methyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.3   0.0   3.9e-11   3.1e-08      46     121 ..      39     118 ..      23     137 .. 0.88

  Alignments for each domain:
  == domain 1  score: 33.3 bits;  conditional E-value: 3.9e-11
                      --TTEEEEES-TT-HHHHHHHHHHHHHHEEEEEES-HHHHHHHHHHHHHHTSS.....TEEEEE--TTT-TTS-T-EEEEE CS
  Ubie_methyltran  46 krgakvlDvagGtgDlafklsdsvgekgkvvvlDinenmLkvgekklkeegki.....nieflqanaeeLpfeddsfDvvt 121
                       +g ++lDv +G g ++  +++ v   g vv++Di+ ++L+ +++ + e  +      ++ f q+n   Lp++ d+fD+v 
       EEA19824.1  39 EKGDRILDVGCGPGTITTGFAKYVS-GGSVVGIDISTEVLQNAKESAAEANVPtegpgSVVFEQGNILGLPYHGDTFDIVY 118
                      5799******************995.799*************99998887665667779*******************985 PP

>> PCMT  Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.0   0.0     1e-09   8.2e-07      68     120 ..      34      86 ..       5     110 .. 0.75

  Alignments for each domain:
  == domain 1  score: 29.0 bits;  conditional E-value: 1e-09
                 HTT.--TT-EEEEES-TTSHHHHHHHHHHCTTCEEEEEESBHHHHHHHHHHHHH CS
        PCMT  68 lle.lkkgarvLevGsGsGyltavlarlvgekgrvvsierikelveeakrnlkk 120
                 ll  ++kg+r+L+vG+G G  t  +a++v   g vv+i+ + e+ ++ak+   +
  EEA19824.1  34 LLPhIEKGDRILDVGCGPGTITTGFAKYVSG-GSVVGIDISTEVLQNAKESAAE 86 
                 333599***********************86.55**********9998875443 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.6   0.0   1.2e-09   9.2e-07      20      81 ..      31      90 ..      25     116 .. 0.90

  Alignments for each domain:
  == domain 1  score: 28.6 bits;  conditional E-value: 1.2e-09
                HHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC CS
         MTS 20 sklLletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle 81
                +++Ll +++k   +++lD+GcG G +++ +ak  +  +v+ +d++++ l+ ake +++ ++ 
  EEA19824.1 31 AAFLLPHIEK--GDRILDVGCGPGTITTGFAKYVSGGSVVGIDISTEVLQNAKESAAEANVP 90
                5799999999..778***************************************99998876 PP

>> CMAS  Mycolic acid cyclopropane synthetase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0   0.0   6.3e-09   4.9e-06      58     111 ..      36      90 ..      10     133 .. 0.79

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 6.3e-09
                 TT--TT-EEEEES-TTSHHHHHHHHHH.--EEEEEES-HHHHHHHHHHHHTS-SS CS
        CMAS  58 lelkpGmtlLdiGcGWGslvrravery.dvkvvglTlSkeqaklakkrvdeldle 111
                  ++++G+++Ld+GcG G++++  ++   + +vvg+ +S+e  + ak++ +e+++ 
  EEA19824.1  36 PHIEKGDRILDVGCGPGTITTGFAKYVsGGSVVGIDISTEVLQNAKESAAEANVP 90 
                 3799*************99887665433789****************99988765 PP

>> Methyltransf_18  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.0   5.6e-07   0.00043      11      63 ..      37      89 ..      32     102 .. 0.93

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 5.6e-07
  Methyltransf_18 11 lvekgsrvaDiGtDHgylpiylvkegkakkviasDinegplekakeniekagl 63
                     ++ekg+r++D+G+  g ++   +k     +v+ +Di+++ l++ake++++a++
       EEA19824.1 37 HIEKGDRILDVGCGPGTITTGFAKYVSGGSVVGIDISTEVLQNAKESAAEANV 89
                     699********************************************999887 PP

>> Methyltransf_32  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0   9.9e-07   0.00078      24      75 ..      39      88 ..      21     104 .. 0.84

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 9.9e-07
  Methyltransf_32 24 sgaltvvDvGaGkgYLsfvlalkekeyklkvvgidakeelvekaekraeklg 75
                     ++  +++DvG+G g  +   a      + +vvgid+++e+ ++a++ a++ +
       EEA19824.1 39 EKGDRILDVGCGPGTITTGFAK--YVSGGSVVGIDISTEVLQNAKESAAEAN 88
                     44689***********999988..3479******************998876 PP

>> PrmA  Ribosomal protein L11 methyltransferase (PrmA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0   3.9e-06    0.0031     158     210 ..      37      90 ..      24     119 .. 0.81

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 3.9e-06
        PrmA 158 lvkegeevlDvGtGSGiLaiaaak.LgakkvvavDiDevAvkvakeNaelNkve 210
                 ++++g+++lDvG+G G ++ + ak +   +vv++Di    ++ ake a+  +v 
  EEA19824.1  37 HIEKGDRILDVGCGPGTITTGFAKyVSGGSVVGIDISTEVLQNAKESAAEANVP 90 
                 578999**********9999866527889***************9998776665 PP

>> Methyltransf_4  Putative methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   6.6e-06    0.0052       5      48 ..      44      87 ..      40     113 .. 0.92

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 6.6e-06
                    EEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHC CS
  Methyltransf_4  5 vleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieal 48
                    +l++GcG G+++   Ak     +++Gi+i+++v++++ +++++ 
      EEA19824.1 44 ILDVGCGPGTITTGFAKYVSGGSVVGIDISTEVLQNAKESAAEA 87
                    79**********************************99988876 PP

>> UPF0020  Putative RNA methylase family UPF0020
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.7   0.0    0.0002      0.15      78     127 ..      66     119 ..      17     125 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.0002
                 -EEEEES-HHHHHHHHHHHHHTT-G....GGEEEEE--GGG--STTS---EEEE CS
     UPF0020  78 klygsDldrrvvqgareNaekagvg....dliefsqadaakLrlkegevdvivt 127
                 +++g+D+  +v+q a+e a +a+v     +++ f+q ++  L+   + +d++ +
  EEA19824.1  66 SVVGIDISTEVLQNAKESAAEANVPtegpGSVVFEQGNILGLPYHGDTFDIVYS 119
                 489*******************99633336899*********966668998866 PP

>> RrnaAD  Ribosomal RNA adenine dimethylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   1.7e-05     0.013      28      70 ..      38      82 ..      31      90 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 1.7e-05
                GGTTSEEEEES-TTTCCHHHHHCC-..SEEEEE-S-HHHHHHHHC CS
      RrnaAD 28 leekltvleigpGkGilTeeLakra..kqvvvlElderLakllqk 70
                +e+ + +l++g G+G  T+ +ak++   +vv + + ++ ++  ++
  EEA19824.1 38 IEKGDRILDVGCGPGTITTGFAKYVsgGSVVGIDISTEVLQNAKE 82
                67999********************88888888777766666555 PP

>> FtsJ  FtsJ-like methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   1.5e-05     0.012      19      58 ..      38      87 ..      18     117 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 1.5e-05
                S-TT-EEEECT-TTSHHHHHHCCT.T.-SEEEEEESSSS...........H CS
        FtsJ 19 fkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm...........a 58
                +++g++++D+g++PG  +   ++ +  +g vv++D+              a
  EEA19824.1 38 IEKGDRILDVGCGPGTITTGFAKYVS-GGSVVGIDISTEvlqnakesaaeA 87
                46899*******************97.5********655476666555442 PP

>> Methyltr_RsmB-F  16S rRNA methyltransferase RsmB/F
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   3.3e-05     0.026       7      52 ..      39      83 ..      32      91 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 3.3e-05
                     -TT-EEEESS-TTSHHHHHHHHHTTTTSEEEEEESSCCCHHHHHHH CS
  Methyltr_RsmB-F  7 qeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaen 52
                     +++++ilD+ ++PG  Tt  a+   + g vv +d+++e l++ +e 
       EEA19824.1 39 EKGDRILDVGCGPGTITTGFAKY-VSGGSVVGIDISTEVLQNAKES 83
                     6789******************9.78999******99988887765 PP

>> SepRS_C  O-phosphoseryl-tRNA synthetase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0     0.098        76       4      30 ..      61      88 ..      61      89 .. 0.87
   2 ?    7.8   0.0    0.0044       3.4       7      15 ..     101     110 ..      97     119 .. 0.78

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.098
                EEETTEEEEEE.S-TTTCCHHHHSEEEE CS
     SepRS_C  4 yVYdGnIlGvP.dtekwkearenGvsTG 30
                yV  G+++G+  +te  + a+e  ++++
  EEA19824.1 61 YVSGGSVVGIDiSTEVLQNAKESAAEAN 88
                8999******999999999999888776 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0044
                 TTEEEEEE.S CS
     SepRS_C   7 dGnIlGvP.d 15 
                 +GnIlG+P  
  EEA19824.1 101 QGNILGLPyH 110
                 7*******55 PP

>> MetW  Methionine biosynthesis protein MetW
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   0.00011     0.088       9      48 ..      36      76 ..      29     130 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00011
        MetW  9 elikpgsrvldlGcGdGellellke.ekqvdgrGleldeeg 48
                  i++g r+ld+GcG G++ + +++   + +  G+++++e 
  EEA19824.1 36 PHIEKGDRILDVGCGPGTITTGFAKyVSGGSVVGIDISTEV 76
                57999*************98766430223333566666554 PP

>> TPMT  Thiopurine S-methyltransferase (TPMT)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0    0.0001     0.078      34     109 ..      37     116 ..       7     126 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 0.0001
                 T-S--EEEEEET-TT-HHHHHH-B..TTEEEEEE-S-HHHHHHHHHHHTTSGGGGGEEEE--.............-TTT- CS
        TPMT  34 kakaglrvlvPlCGkaldlvwlAe..qgrevvGvelselAvekffeeanlepkvkelsgvkeysagei.el.lcgdvFtl 109
                 + ++g r+l  +CG ++  + +A+   g +vvG+++s   ++++ e a +    +e  g  ++++g+i +l + gd F++
  EEA19824.1  37 HIEKGDRILDVGCGPGTITTGFAKyvSGGSVVGIDISTEVLQNAKESAAEANVPTEGPGSVVFEQGNIlGLpYHGDTFDI 116
                 456778999999*****9999*9855699**************8777777555566666666667776334478888875 PP

>> Methyltransf_15  RNA cap guanine-N2 methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00019      0.14       3      42 ..      43      84 ..      41      93 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00019
  Methyltransf_15  3 vilDlfsGaGGnviqfalv..fekviaieinleklacaqhNa 42
                      ilD+ +G G  +  fa++  + +v++i+i++e l+ a++ a
       EEA19824.1 43 RILDVGCGPGTITTGFAKYvsGGSVVGIDISTEVLQNAKESA 84
                     69****************977789*********999988765 PP

>> Methyltransf_9  Protein of unknown function (DUF1698)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00025       0.2     107     152 ..      34      78 ..      10     135 .. 0.68

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00025
                     HGGGS.--TT-EEEEET-TTSHHHHHHHHC.T-SEEEEE---HHHHH CS
  Methyltransf_9 107 vlphlsdlkgrtildvGcgnGyhlwrmvge.gaklvvGidPselfli 152
                     +lph+   kg +ildvGcg G      +      +vvGid s+  l 
      EEA19824.1  34 LLPHI--EKGDRILDVGCGPGTITTGFAKYvSGGSVVGIDISTEVLQ 78 
                     68999..5899**********88766554313457889988776654 PP

>> CheR  CheR methyltransferase, SAM binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.0    0.0046       3.6      65      83 ..      65      83 ..      16      91 .. 0.75
   2 ?    2.0   0.0      0.15   1.2e+02     119     157 ..      96     134 ..      83     150 .. 0.81

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0046
                EEEEEEESSCHHHHHHHHT CS
        CheR 65 vkilAtDidlkvlekAkag 83
                 +++++Di+++vl++Ak+ 
  EEA19824.1 65 GSVVGIDISTEVLQNAKES 83
                479*************986 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.15
                 TEEEEE--TTT-SGGG--EEEEEE-SSGGGC-CHHHHHH CS
        CheR 119 lvkFeklnllekksvlgklDvifcrnvliYfdeetqekv 157
                  v Fe+ n+l      + +D++ +  v+  f +++  ++
  EEA19824.1  96 SVVFEQGNILGLPYHGDTFDIVYSSQVFGHFPPPDLPEL 134
                 699*******95556678*********999988876665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (156 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       376  (0.0209716); expected 358.6 (0.02)
Passed bias filter:                      361  (0.020135); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                        23  (0.00128284); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              23  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1059.57
//
Query:       EEA19825.1  [L=341]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      2e-05   24.7   0.6       0.17   12.1   0.0    3.3  2  Pentapeptide_4  Pentapeptide repeats (9 copies)
  ------ inclusion threshold ------
       0.57   10.2  15.7       0.77    9.7   5.5    3.0  3  CfAFP           Choristoneura fumiferana antifreeze protein (


Domain annotation for each model (and alignments):
>> Pentapeptide_4  Pentapeptide repeats (9 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.1   1.7    0.0028        25      19      44 ..     100     125 ..      27     157 .. 0.62
   2 !   12.1   0.0   1.8e-05      0.17      14      64 ..     179     229 ..     172     234 .. 0.83

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0028
  Pentapeptide_4  19 searlrdcnFtecrlsnvnFdecnls 44 
                       ++ ++c +t++  +  ++++cn+s
      EEA19825.1 100 QRSEVHGCAITDSTVDRSTLNNCNVS 125
                     22333333333333333333333332 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 1.8e-05
  Pentapeptide_4  14 snvnFsearlrdcnFtecrlsnvnFdecnlsdvdfaevdlkrasFsgcnlk 64 
                     +++++++a +  ++ + +++s++   +c+++ +df+++ l +  +++ +l 
      EEA19825.1 179 ERTELKTAVITKSRVERSKISDCDVMDCVIERTDFQGMILQYGIWKRGDLV 229
                     578888899999999999999999999999999999999888888877775 PP

>> CfAFP  Choristoneura fumiferana antifreeze protein (CfAFP)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   1.8    0.0091        82      37     105 ..      31      94 ..      26      97 .. 0.74
   2 ?    9.7   5.5   8.6e-05      0.77      41     106 ..      85     158 ..      56     176 .. 0.60
   3 ?    6.7   0.3   0.00077       6.9      38      79 ..     172     213 ..     149     219 .. 0.80

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.0091
       CfAFP  37 stltncyidnselessictrsqysdayvkksvttdcnidksqlygttctgsrydGvyitsstttgtris 105
                 st+ nc   n    ++ ++rs  s++ v++ v ++         +tt  +   +G++i  st  +++i+
  EEA19825.1  31 STIKNCTFKNLSA-TTNISRSIVSESTVMQEVESSP----MSSDLTTAKAKSKKGMHIGRSTIDNSQIL 94 
                 7888898888777.7778888888888877665443....23345777777779999999999999886 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 8.6e-05
       CfAFP  41 ncyidnsel.essictrsqy.....sdayvkksvttdcnid.ksqlygttctgsrydGvy.itsstttgtrisG 106
                    idns++ +ss + rs+      +d+ v +s+  +cn++ +s++  tt  ++++ G + +  s  +++ ++G
  EEA19825.1  85 RSTIDNSQIlNSSNVQRSEVhgcaiTDSTVDRSTLNNCNVSaQSHIERTTAKTTKFIGPKrVERSEFSDSVVLG 158
                 34566666656666666654111114566667777888885367888888888888774314455555555555 PP

  == domain 3  score: 6.7 bits;  conditional E-value: 0.00077
       CfAFP  38 tltncyidnselessictrsqysdayvkksvttdcnidksql 79 
                 ++    i+++el+++++t+s+ + +++ ++ + dc i+++++
  EEA19825.1 172 VAGKAVIERTELKTAVITKSRVERSKISDCDVMDCVIERTDF 213
                 45567899999*********9999999999999999998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (341 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       601  (0.0335211); expected 358.6 (0.02)
Passed bias filter:                      249  (0.0138881); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.37s 00:00:01.00 Elapsed: 00:00:00.57
# Mc/sec: 1806.37
//
Query:       EEA19826.1  [L=238]
Description: hypothetical protein PMAA_005940 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (238 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       461  (0.0257125); expected 358.6 (0.02)
Passed bias filter:                      357  (0.0199119); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.65u 0.33s 00:00:00.98 Elapsed: 00:00:00.59
# Mc/sec: 1223.55
//
Query:       EEA19827.1  [L=559]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.6e-07   29.6   7.2    1.2e-06   28.5   7.2    1.6  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
     0.0068   15.3   0.2      0.022   13.6   0.0    1.9  3  Glyco_hydro_71  Glycosyl hydrolase family 71
  ------ inclusion threshold ------
        0.6    9.9   2.9       0.95    9.3   2.9    1.2  1  FCP1_C          FCP1, C-terminal


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.5   7.2   2.1e-10   1.2e-06       1      36 [.      12      47 ..      12      51 .. 0.92

  Alignments for each domain:
  == domain 1  score: 28.5 bits;  conditional E-value: 2.1e-10
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfyses 36
                ++C  C k K++Cd  +P+Cs+C k+++ C++++ +
  EEA19827.1 12 RSCHGCVKVKRRCDLLFPECSRCFKKGVRCQYINIP 47
                59*****************************88765 PP

>> Glyco_hydro_71  Glycosyl hydrolase family 71
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   0.1      0.82   4.9e+03      87     107 ..      79      99 ..      65     117 .. 0.56
   2 ?   -2.5   0.0      0.29   1.7e+03      75     114 ..     202     240 ..     195     261 .. 0.75
   3 !   13.6   0.0   3.7e-06     0.022     229     292 ..     447     504 ..     439     522 .. 0.76

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 0.82
  Glyco_hydro_71  87 ashpaqlkvngkplvSTFeGe 107
                     +++++q k+++ ++v T + e
      EEA19827.1  79 QQQQQQRKIHNAVVVGTIKAE 99 
                     233333444445666665555 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.29
  Glyco_hydro_71  75 pksevislikkyashpaqlkvngkplvSTFeGeknaedwa 114
                     p +e+++l + y++ +  +++ +++ +STF  ++  + ++
      EEA19827.1 202 PVREIRALCALYENDSDDYQL-SSVKLSTFLQHQIFSLIQ 240
                     447899999999999999999.889999998887643333 PP

  == domain 3  score: 13.6 bits;  conditional E-value: 3.7e-06
  Glyco_hydro_71 229 NDygEShYigplkekkaqdgsskyvegmpHdgwrdllkyyiaayKtgskkpaitedklvlwyRp 292
                     ND   S+ i    + + q+      + +  +++r++l+ +i+ayK+g  k +i++ +l++w+R 
      EEA19827.1 447 NDAPHSDLITRRIT-HLQT---LLSSLHAYHAYRETLPAIIDAYKSG--KLTIEKGQLTFWARS 504
                     66666666655222.3333...4444456789***************..47***********97 PP

>> FCP1_C  FCP1, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   2.9   0.00016      0.95     170     247 ..      66     143 ..      56     148 .. 0.60

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00016
                 XXXXXXXXX....XXX.XXX...XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXSHHH CS
      FCP1_C 170 kkkeeeeeeeeeeeqe.rkpealeakeeeklastssserslaesvprGhkRkleeedaasesskessnedeegssseaD 247
                 +k +++++++++++q+ ++++ ++a    + +++  + ++++  v r  kR ++  d as++ + ss+ d  gss + D
  EEA19827.1  66 TKLTNTRHHQQHQQQQqQQRKIHNAVVVGTIKAEIVQANNTETIVVRLPKRTMSSSDVASDERSVSSD-DSIGSSPNSD 143
                 444444444444433313334444444444555666666666667**************998887765.5677776666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (559 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1010  (0.0563333); expected 358.6 (0.02)
Passed bias filter:                      566  (0.031569); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.79u 0.38s 00:00:01.17 Elapsed: 00:00:00.57
# Mc/sec: 2947.13
//
Query:       EEA19828.1  [L=224]
Description: hypothetical protein PMAA_005960 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (224 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       265  (0.0147805); expected 358.6 (0.02)
Passed bias filter:                      257  (0.0143343); expected 358.6 (0.02)
Passed Vit filter:                        10  (0.000557756); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.57u 0.33s 00:00:00.89 Elapsed: 00:00:00.54
# Mc/sec: 1241.14
//
Query:       EEA19829.1  [L=538]
Description: high affinity methionine permease [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.7e-87  292.3  40.1    5.7e-87  292.3  40.1    1.3  1  AA_permease_2  Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  292.3  40.1   3.2e-91   5.7e-87       1     422 [.      56     488 ..      56     491 .. 0.91

  Alignments for each domain:
  == domain 1  score: 292.3 bits;  conditional E-value: 3.2e-91
  AA_permease_2   1 lsllsafalvigsvigsgifvkn.....laasggpalilwvwiavligslavllvyaElssalprsgGiyvytkaafgkkvaflsawfnwfayvpv 91 
                    l+ ls+++lv+g++ig+gif ++      ++s+g++l++wv++  l+   a+l v +E+++++prsgG+++y++a+++k+   ++ +f++ a++++
     EEA19829.1  56 LGVLSTTFLVVGRIIGTGIFSTPssvtaELGSVGASLMFWVLGLFLAA--AGLCVWLEFACMIPRSGGEKNYLEAVYKKPKLLITIFFAVQAIALG 149
                    789*********************99999999*******999999997..9**************************9999999999999999886 PP

  AA_permease_2  92 l.asilsvaasyllnalgpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfssl..stetdtffp 184
                    + as+++v+a+y+l+a++ ++  + w  ++iai+++++++l++ + +k++ +  n+++ +ki ++l++++++g+++++gg  s +  +    + f+
     EEA19829.1 150 FtASGCVVFAQYILTAADVTV--TEWGKRGIAIGVIVFITLFHTFLPKWGVRGMNVITGIKI-IVLLFIVVTGWVVLGGGVKSVPdpHASFRNAFA 242
                    62677***********98877..5567***********************************.8***************99997766555555555 PP

  AA_permease_2 185 ngwpg...vllgllivlwsfdGfesaanvseevkk..kdvpkaifigllivlvlyllvniaflgvvpddeianlsnlgsvaalffeavggkvvaii 275
                    + + +   ++ +l+ vl +++G+++a++v++ev+   ++v++a+++glli+++ly++ nia++++ +++e+a+++ +  +aa f+ +v+g +++++
     EEA19829.1 243 GSNHSgnlYATALFKVLNAYAGWSNAMYVLNEVRDpvRTVKIAGPLGLLICGILYIFANIAYYAAATPEEVAKSGVT--IAAFFMYKVFGHAAQRA 336
                    54443333799*********************888789**********************************97764..6**************** PP

  AA_permease_2 276 vvilialsllgaintavigssrvlealardgvlP..rffakvnkfgspiraiiltaivslillllfllassaaynfllsvsslgliisyllliiga 369
                    +++l+a+s++g+++t+++++srv+++la++gv+P  rf+a++++fgsp++++ l++i s+i+++++ +  ++aynf+l++  +++ ++++l+++g+
     EEA19829.1 337 LSVLLAISAFGNVLTVTFAQSRVNQELAKEGVIPfpRFWASSWPFGSPSAGLLLHFIPSFIVIVAIPF--GDAYNFILDLEGYPSSVVNFLVVFGL 430
                    ************************************************************99999999..58************************ PP

  AA_permease_2 370 lilrkkrphlkr.pgk.ilvaiigalfllfllvalffppkgpatqssliyt...iilt 422
                    ++lr+k+ph  r ++  +++a++++    f lva+f+ p g +  +sl y+   ++++
     EEA19829.1 431 FYLRFKEPHTHRsFKVwWPIAAFFMAAQGFQLVAPFLRPPGGKGDTSLPYWlyaVVGI 488
                    **********99655447*************************999988886434444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (538 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       902  (0.0503096); expected 358.6 (0.02)
Passed bias filter:                      386  (0.0215294); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.46
# Mc/sec: 3504.72
//
Query:       EEA19830.1  [L=65]
Description: hypothetical protein PMAA_005980 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (65 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       249  (0.0138881); expected 358.6 (0.02)
Passed bias filter:                      204  (0.0113782); expected 358.6 (0.02)
Passed Vit filter:                         6  (0.000334653); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.43
# Mc/sec: 453.51
//
Query:       EEA19831.1  [L=499]
Description: beta-1,6-glucanase Neg1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.7e-27   95.2   4.6    2.7e-26   92.4   4.6    2.2  1  Glyco_hydro_30   Glycosyl hydrolase family 30 TIM-barrel doma
    3.3e-08   33.6   0.9    9.7e-08   32.1   0.9    1.8  1  Glyco_hydro_30C  Glycosyl hydrolase family 30 beta sandwich d
  ------ inclusion threshold ------
      0.016   14.4   7.2      0.017   14.3   0.7    2.8  2  Glyco_hydro_59   Glycosyl hydrolase family 59


Domain annotation for each model (and alignments):
>> Glyco_hydro_30  Glycosyl hydrolase family 30 TIM-barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.4   4.6   4.6e-30   2.7e-26       1     348 []      75     425 ..      75     425 .. 0.79

  Alignments for each domain:
  == domain 1  score: 92.4 bits;  conditional E-value: 4.6e-30
                     --EEEEE--HHHHHHHHTS-HHHHHHHHHHHHSTTTT---EEEEEES--SSSSS.---ST-S..TT-TT-TT----HHHHTTHHHHHHHHHHH-S CS
  Glyco_hydro_30   1 ikGfGstlsdasganlkslsdkladlllkqyfsdeGlnlqigrvpiastdfssr.vytyddt..addyslanfsltkedtklkipyikraqkynq 92 
                     i GfG++++da+   + +ls      ll+  ++ +G ++ ++r  i s+d+s+  vytydd+  a d s+  f++    t +   ++ + + +++
      EEA19831.1  75 ITGFGAAVTDATVTSFNTLSSANLSQLLNVLMTSTGADFSLMRHTIGSSDLSGDpVYTYDDNggAVDTSMSGFNIGDRGTAMA-EMLATMKSLQP 168
                     78********************99****************************8549*****9445799*******99988775.5677778999* PP

                     S-EEEEEES---GGGBTTSSSS........SS-BBSS-TTS..........HHHHHHHHHHHHHHHHHHHTT--ESEEESSSSGGGGGSTT-SSS CS
  Glyco_hydro_30  93 dlkllaapwaapgwlkttkavk........GkGalkGkagd..........iyhkayakyfvkfleeyaksklsfwglsteneptaGsdkktklq 169
                     +lk+l + w+ p+w+k ++ ++        G+ + + + +d           y   +a+yfvk++++y+  + ++ +++ +nep   s+++++  
      EEA19831.1 169 NLKVLGSSWSPPAWMKLNNRLDkstknttlGQSITNNTLDDghsgtgvgsaGYSSEFAQYFVKYIQAYTALGANIDAITIQNEPL-NSQSGYPT- 261
                     ***************97654321111111255554433333212212222258999****************************5.46777775. PP

                     --B--HHHHHHHHHHTHHHHHHTSTT.TTSEEEEEEEEGGGTTHHHHHHHTSHHHHTTEEEEEEEETTTS-HHHHHHHHHHHSTTSEEEEEEEES CS
  Glyco_hydro_30 170 slgftaetqrdfikrdlGpalaassagknvkllilddnrgnlpkwadvvlndkdaakyvsGiavhayqdaeadkhldethkkfpnvlllgtease 264
                      + +    q  +i+  +Gpala++  g +  +   ddn + +p + + vl+   a++yv+ +a h y  ++  + l++ ++k pnv  + te   
      EEA19831.1 262 -MYMLDSEQGSLIQSYVGPALASA--GLKTAIWAYDDN-TDVPSFPQNVLD--TASQYVNTVAWHCYASSNDWSVLTNFKNKNPNVTQYMTECWT 350
                     .55567789************976..558889999998.579********6..589*********************************999744 PP

                     S-STTS-SS-TT-HHHHHHHHHHHHHHHHTTEEEEEEEESEB-TTS---TT--..-B--SEEEEGGGTEEEE-HHHHHHHHHHTTS CS
  Glyco_hydro_30 265 GskskdqsvdyGsfdraadyasdildnlnnwvvGwternlvldaeGGpswvsd..fvdapviafialaqfykqpmfyalahfskfi 348
                                G++  + +++   +  l+nw  G   + l  ++  Gp   ++  ++   +++     ++  q  +y +a +skfi
      EEA19831.1 351 P--------PSGKWYHSSNFT---MGPLQNWASGVMAWTLGTNSSYGPHLSEGgcHTCQGLVTVNDDGTYTLQLAYYLMAQYSKFI 425
                     3........457777776665...56677888888888899999999998876223444556666666777788899999999997 PP

>> Glyco_hydro_30C  Glycosyl hydrolase family 30 beta sandwich domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.1   0.9   1.6e-11   9.7e-08      14      64 ..     439     493 ..     429     494 .. 0.87

  Alignments for each domain:
  == domain 1  score: 32.1 bits;  conditional E-value: 1.6e-11
  Glyco_hydro_30C  14 s....snvetvAFlnpDGsivvvilNrsessvtitvsdsskskgslsvparSivT 64 
                      +    +++++vA lnpDG+++vvi N+ +s+v ++v+++s+++ s  vp +S+vT
       EEA19831.1 439 TrsgvGGIQSVASLNPDGTRTVVIQNTLSSDVYVNVTTTSGQEWSGIVPTQSVVT 493
                      2333479********************88**********999999999******9 PP

>> Glyco_hydro_59  Glycosyl hydrolase family 59
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.7   2.9e-06     0.017      78     143 ..     158     252 ..      77     266 .. 0.83
   2 ?    1.6   0.8     0.022   1.3e+02      72     130 ..     323     386 ..     308     398 .. 0.71

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2.9e-06
  Glyco_hydro_59  78 wlakeAkkrnpdikldileWgaPgwlk...............................ksaekasektaeylkswlkgakktygldidyiaglrn 141
                      +++  k+ +p++k+ + +W+ P+w+k                                 ++ +s++ a+y+++++++     g +id i  ++n
      EEA19831.1 158 EMLATMKSLQPNLKVLGSSWSPPAWMKlnnrldkstknttlgqsitnntlddghsgtgVGSAGYSSEFAQYFVKYIQAY-TALGANIDAI-TIQN 250
                     578899**********************999999999999999999999999999887667889999999999999876.7799999999.8888 PP

  Glyco_hydro_59 142 ek 143
                     e 
      EEA19831.1 251 EP 252
                     85 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.022
  Glyco_hydro_59  72 erGyefwlakeAkkrnpdikldile.WgaP..gwlkksaekasektaey...lkswlkgakktyg 130
                     +   ++ ++++ k++np+++ ++ e W+ P  +w + s+++++    ++   ++ w  g +++yg
      EEA19831.1 323 ASSNDWSVLTNFKNKNPNVTQYMTEcWTPPsgKWYH-SSNFTMGPLQNWasgVMAWTLGTNSSYG 386
                     56678***************9999769988444886.4555544444442225666667666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (499 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       557  (0.031067); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.49
# Mc/sec: 3065.43
//
Query:       EEA19832.1  [L=634]
Description: glutaminyl-tRNA synthetase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.2e-94  315.4   0.0    4.6e-94  314.8   0.0    1.2  1  tRNA-synt_1c     tRNA synthetases class I (E and Q), catalyti
      1e-27   97.2   0.0      3e-27   95.6   0.0    1.8  1  tRNA-synt_1c_C   tRNA synthetases class I (E and Q), anti-cod
  ------ inclusion threshold ------
      0.059   13.5   0.0         14    5.7   0.1    2.4  2  PseudoU_synth_2  RNA pseudouridylate synthase


Domain annotation for each model (and alignments):
>> tRNA-synt_1c  tRNA synthetases class I (E and Q), catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  314.8   0.0   7.7e-98   4.6e-94       3     313 ..      95     406 ..      93     407 .. 0.96

  Alignments for each domain:
  == domain 1  score: 314.8 bits;  conditional E-value: 7.7e-98
                   EEEE---SSSS-BHHHHHHHHHHHHHHHHTT-EEEEE....E--SSCCC--HHHHHHHHHHHHHTT---SSEEEEGGGGHHHHHHHHHHHHHTTSEE CS
  tRNA-synt_1c   3 rtRfaPePtGyLHiGhakaallnylfAknnnGkfilR....ieDTdperekeeaeesiledlkwlgikwdekptyqsdrfdelkkyaeeLikkGkAY 95 
                   +tRf+PeP+G+LH+Ghaka+ +n++fA++++G   +R    ++DT+pe e+e +++si++ ++wlg+k+ + +ty+sd f++l+++ae+Li+  kAY
    EEA19832.1  95 VTRFPPEPNGFLHLGHAKAIAINFGFARYHGGV-TVRipfvFDDTNPEAEEEIYFTSIIDVVEWLGFKP-HAITYSSDNFQRLYDLAEKLIEIEKAY 189
                   69**************************99885.44533337***************************.99************************* PP

                   EE-STHHHHHHHHCCSS....HSS-TTTTS-HHHHHHHHHHHHHTTHSTTTS-EEEESSBTTSS.GGGSSTEEEEEEESGGGSBTTTBTSTSEEE-H CS
  tRNA-synt_1c  96 vcectkeeleeereeqe....klgskerdrydeenlklfeeemkkgkaegekavvRlkideess.vefrDlvrgriklepqeihdlvivksdiyPtY 187
                   vc+c++ e++ +r+ ++    ++ +++ ++ ++ nl+ f ++m++gk++ ++a +R+k+d  s   + +Dl ++r+  +p   h+++++k+ iyPtY
    EEA19832.1 190 VCHCNEAEIKLQRGGEKgtspRYRCAHAEQDVQTNLQKF-RDMRDGKYQPQAAFLRMKQDITSGnPQNWDLAAYRVLSKP---HHRTGDKWVIYPTY 282
                   *************987788889999**************.9*******************99888***************...************** PP

                   HHHHHHHHHHTT-SEEEEEGGGGCCHHHHHHHHHHTT-S.-EEEEEE--EEETTSB-SHHHHHHHHHTTSSSSTT-TTSCBHHHHHHCTB-HHHHHH CS
  tRNA-synt_1c 188 dfavvidDaleeithvlrteefldntpkyiwllealglevppfiheylrlnlekkklSKRklsllvdekqvkewddlreallnflrrlGwtpekere 284
                   df+++i+D++e+ith+l+t+ef++++++y wl + l+l+ +p+++ey rln++++ +SKR l+ l+d k+v++wdd+r+ +l +lrr+G++p ++ +
    EEA19832.1 283 DFTHCIVDSIEGITHSLCTTEFQQSRESYEWLNKTLSLY-EPMQREYGRLNVTGTIMSKRGLKKLIDGKHVRGWDDPRLYTLIALRRRGVPPGAILS 378
                   ***************************************.********************************************************* PP

                   HHHHHCCCSSS.EEEEHHHHHHHHHHHHH CS
  tRNA-synt_1c 285 lftreeliksfdlnresksleafdrkkLe 313
                   ++++ ++++s    ++ k++e  +r++Le
    EEA19832.1 379 FINELGVTTSN-SLIQLKRFEQSVRNYLE 406
                   **********9.88999999999988876 PP

>> tRNA-synt_1c_C  tRNA synthetases class I (E and Q), anti-codon binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.6   0.0     5e-31     3e-27       2     157 ..     410     577 ..     409     581 .. 0.93

  Alignments for each domain:
  == domain 1  score: 95.6 bits;  conditional E-value: 5e-31
  tRNA-synt_1c_C   2 pRymaVldpvkvtienlpeg..keeelevplhpknpelgtrkvpfskeiyiereD........akrlkpgeevrLke.lynikveevekdesgev 85 
                     pR+m+Vl+p++v+ie+ ++   +e  l++p+ pk p  gt+ + +++++yi+r+D        ++rl+pg++v L +  y i+++ ++kd++g+v
      EEA19832.1 410 PRLMMVLEPLRVVIEDADSLesSERDLTIPFSPKIPAFGTHPLRLTSTVYIDRSDfrevdskdYFRLAPGKTVGLLQmPYPITATTFSKDADGNV 504
                     9**************9844445999*************************************************99968**************** PP

  tRNA-synt_1c_C  86 telkleydgesleearkkkgiihWvsaeeaveaevrlYdrLfkeee.de...dfl..lnpdslkvleeglaepalanl 157
                     te+++ +++e +    k+k+ i+Wv++  + +aevr+   Lfk+e+ ++    fl  + p+s++++ ++l+ep +++ 
      EEA19832.1 505 TEVRAVFQKEGK----KPKTYIQWVPE-GSRKAEVRVHTALFKSEDpASvegGFLndISPNSETIYPDALLEPGFEEI 577
                     ********9777....**********5.89999**********9997778988889********99*******99875 PP

>> PseudoU_synth_2  RNA pseudouridylate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.1    0.0023        14      61     132 ..     169     235 ..     164     277 .. 0.74
   2 ?    5.2   0.0    0.0033        20     112     159 ..     494     539 ..     461     540 .. 0.87

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0023
  PseudoU_synth_2  61 seaanklakafeerk.vrKkYlalvfgapeeeegaikkkiskdtekqegarrkaeeldgkkavtylkvlksgs 132
                      s+  ++l ++ e+   ++K+Y+++++    e+e +++   +k    + ++r+  +e+d +    +++ ++ g+
       EEA19832.1 169 SDNFQRLYDLAEKLIeIEKAYVCHCN----EAEIKLQRGGEK--GTSPRYRCAHAEQDVQTNLQKFRDMRDGK 235
                      5555666665555545*********7....777777777777..88888899999999999999998888883 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0033
  PseudoU_synth_2 112 kaeeldgkkavtylkvlksgsseksakvslveleletGrkhQiRvhla 159
                      +++ +d+   vt ++ + ++  e +++ ++++ ++e  rk ++Rvh a
       EEA19832.1 494 TTFSKDADGNVTEVRAVFQK--EGKKPKTYIQWVPEGSRKAEVRVHTA 539
                      66778888888888888888..8999********************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (634 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       850  (0.0474092); expected 358.6 (0.02)
Passed bias filter:                      624  (0.0348039); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.43
# Mc/sec: 4471.32
//
Query:       EEA19833.1  [L=827]
Description: DUF1212 domain membrane protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.6e-74  248.8  18.9    1.5e-67  227.5   5.5    2.4  2  ThrE           Putative threonine/serine exporter
    2.8e-11   43.7  10.1    2.8e-11   43.7  10.1    3.2  2  ThrE_2         Threonine/Serine exporter, ThrE
  ------ inclusion threshold ------
       0.01   15.9   0.3       0.24   11.5   0.1    2.3  2  AIRS_C         AIR synthase related protein, C-terminal domai
       0.18   11.0   0.1        2.9    7.1   0.0    2.2  2  Peptidase_U57  YabG peptidase U57


Domain annotation for each model (and alignments):
>> ThrE  Putative threonine/serine exporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  227.5   5.5   3.4e-71   1.5e-67       1     240 [.     378     628 ..     378     629 .. 0.94
   2 !   26.9   5.5   6.3e-10   2.8e-06     114     198 ..     657     741 ..     647     753 .. 0.88

  Alignments for each domain:
  == domain 1  score: 227.5 bits;  conditional E-value: 3.4e-71
        ThrE   1 dlilrlGeiLlesGaetyrvedtmkriaralgleevevfvtptsiivsvdeeeesittvrrv.rsrgvnleklsevnelsreiaageisleeaeerLde 98 
                 ++++ l+++L+++Ga+t+r+e++m+++ar+l++ +++++++p ++iv +d+  + +t+++ v   +gv+l++l+++++++++++++ i++eea+++L+e
  EEA19833.1 378 RFLMGLCRALMKFGAPTHRLEEYMQMTARVLEV-DAQFLYLPGCMIVAFDDSTTRTTEFKLVrVAQGVDLSRLADTHSVYKNVVHDMIGVEEATKQLEE 475
                 68999****************************.9**************766666666999999*********************************** PP

        ThrE  99 Ierskpryprwlvvlaaglaaaafallf.ggdwidflvaflagllggllrlll.akrglnsfvleavaaflasllallavslglgln.........pda 186
                 I+++kpr+p+w+ v+++gla+a++++++ ++++id++++fl+g+++g+++l++ +k+ l+s+v+e++a +l+s++a++++s+ +g+          ++ 
  EEA19833.1 476 IMNRKPRFPTWFLVFMYGLASATVGPFAfQARPIDMPISFLLGCMLGFMQLVMaQKSALYSNVFEVCATVLTSFFARAFGSIRWGIIdgkqqylfcFSG 574
                 **************************998************************99**************************8443333445677768** PP

        ThrE 187 iiigsillLvPGlpltnavrDllsgdlvsGlaRlveailialaiafGivlalsl 240
                 i++++i+l++PG+ +++++++l+s+++++G++R+v+ai+++l++++Gi++++++
  EEA19833.1 575 IAQSAIALILPGFLVLCSSLELQSHQMIAGSIRMVYAIIYSLFLGYGITVGVTI 628
                 ***************************************************987 PP

  == domain 2  score: 26.9 bits;  conditional E-value: 6.3e-10
        ThrE 114 aaglaaaafallfggdwidflvaflagllggllrlll.akrglnsfvleavaaflasllallavslglglnpdaiiigsillLvPG 198
                 ++  +   ++++ +g++++++v+++++++g++++++  +++g ns v+++++af++++l+ l  +l ++ +++++i+ +i +LvP 
  EEA19833.1 657 FVVAMTIWIVVINQGKFKQAPVMMVIAFVGYVVNYFStKRIGSNSEVANTLGAFVIGILGNLYSRL-WHGHAATAILPAIFVLVPS 741
                 4555666778888***********************98999********************99997.78999*************5 PP

>> ThrE_2  Threonine/Serine exporter, ThrE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.9   9.2         4   1.8e+04      24     127 ..     512     626 ..     489     628 .. 0.56
   2 !   43.7  10.1   6.3e-15   2.8e-11       6     128 ..     659     812 ..     654     813 .. 0.79

  Alignments for each domain:
  == domain 1  score: -4.9 bits;  conditional E-value: 4
      ThrE_2  24 lvagllGav.gwlvylllmelgvsialasflaalaigllsellArriktPv.....tvfli.....pgllplvPGlaaYktvlslvqgnleeavengie 111
                 +++ llG++ g++  +++++     ++  ++a+++ +++++ ++ +    +      +f +     +++  + PG  +  + l+l ++++      ++ 
  EEA19833.1 512 PISFLLGCMlGFMQLVMAQKSALYSNVFEVCATVLTSFFARAFGSIRWGIIdgkqqYLFCFsgiaqSAIALILPGFLVLCSSLELQSHQMIAGSIRMVY 610
                 555555544144433333345555566666666666666666654432211111012222200010345667788888888888888888888888888 PP

      ThrE_2 112 alliagalavGlvlvs 127
                 a++  + l  G+++  
  EEA19833.1 611 AIIYSLFLGYGITVGV 626
                 8888888888877765 PP

  == domain 2  score: 43.7 bits;  conditional E-value: 6.3e-15
      ThrE_2   6 fiaalgfavifnvpkrallvagllGavgwlvylllme.lgvsialasflaalaigllsellArriktPvtvflipgllplvP.GlaaYktvlslv.... 98 
                 +  ++   vi++ + ++ +v+ +++ vg++v+++ ++ +g++ ++a+ l+a++ig+l++l++r+ +  + + + p+++ lvP Glaa  +++s +    
  EEA19833.1 659 VAMTIWIVVINQGKFKQAPVMMVIAFVGYVVNYFSTKrIGSNSEVANTLGAFVIGILGNLYSRLWHGHAATAILPAIFVLVPsGLAASGSLISGIasad 757
                 555666677888888*******************99999*******************************************75555556666553444 PP

      ThrE_2  99 .........qgn.................leeavengiealliagalavGlvlvsl 128
                          + n                  + +++ g+ ++++a+++ vGl+++ l
  EEA19833.1 758 qirsnvstpK-NqtstggggepgvvsatsNTSVFNLGFGMVQVAIGITVGLFMAAL 812
                 4433334441.0444555555666666559999*******************9876 PP

>> AIRS_C  AIR synthase related protein, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.1     0.051   2.3e+02      63      80 ..     250     267 ..     247     273 .. 0.86
   2 ?   11.5   0.1   5.4e-05      0.24      35      83 ..     300     348 ..     255     353 .. 0.78

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.051
                 EEEE--TTHHHHHHHHHH CS
      AIRS_C  63 aahDvTgGGLlgalaema 80 
                 a++ ++gGG+lg+l  + 
  EEA19833.1 250 AMTRMSGGGVLGNLLKLY 267
                 8999**********8875 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 5.4e-05
                 TSEHHHHHHHHHHHHHHHHHHHHHTTECEEEE--TTHHHHHHHHHHHTT CS
      AIRS_C  35 avqlgdvlleptliyvkralaalkglvkaahDvTgGGLlgalaemapas 83 
                  + ++ + +e+ ++y k++    + l+ aa ++T+ G +++ ++m+ a+
  EEA19833.1 300 TSGVSTPKREKVKWYNKDKNKSTSSLIGAASHLTAAGAANHSNRMMSAA 348
                 555888999999999999999999*********************9886 PP

>> Peptidase_U57  YabG peptidase U57
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.0     0.039   1.7e+02      43      87 ..     183     226 ..     180     260 .. 0.64
   2 ?    7.1   0.0   0.00064       2.9      22     120 ..     314     421 ..     309     429 .. 0.77

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.039
  Peptidase_U57  43 dapldDLekveeeevkekkkkleekveeslkkllkerkeeeekkk 87 
                    +ap++DL+  ++++ +++++++ ++++e+ + + +e ++++++++
     EEA19833.1 183 NAPVSDLTDDHRKTEEDRQRDQAHSTSEAHRLV-REMTQHHTEQR 226
                    689999998777766666666555555555555.33333322222 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.00064
  Peptidase_U57  22 ikkeeekkiaiLkGlevRliadapldDLekveeeevkekkkkleekveeslkkllkerkeeee.........kkkkkekkekekeeafelpgkvLh 108
                     +k+++k++  L G    l+a    +  + + ++  k++k+  + + e++++ +++  +  ++         +  k  + +++ ee+++++++vL 
     EEA19833.1 314 YNKDKNKSTSSLIGAASHLTAAGAANHSNRMMSAASKRRKQGGKPRLEDEIRVTVHIAEIIARhrflmglcrALMKFGAPTHRLEEYMQMTARVLE 409
                    56788888999999999999988888888888888888888888888888887744433333344666777655566667778899********** PP

  Peptidase_U57 109 lDgdeeYlekcl 120
                    +D++  Yl  c+
     EEA19833.1 410 VDAQFLYLPGCM 421
                    ********9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (827 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1157  (0.0645323); expected 358.6 (0.02)
Passed bias filter:                      515  (0.0287244); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.77u 0.30s 00:00:01.07 Elapsed: 00:00:00.49
# Mc/sec: 5072.21
//
Query:       EEA19834.1  [L=267]
Description: hypothetical protein PMAA_006020 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0034   17.0   0.1      0.012   15.2   0.1    1.8  1  SLT       Transglycosylase SLT domain
  ------ inclusion threshold ------
      0.044   13.9   1.2      0.064   13.3   0.1    1.7  2  STG       Simian taste bud-specific gene product family


Domain annotation for each model (and alignments):
>> SLT  Transglycosylase SLT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.1   1.4e-06     0.012       2      99 ..     121     232 ..     120     244 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1.4e-06
                 HHHHHHHHHTS-HHHHHHHHHHHHTT-TT-B-...TTSEBTTTTBETTTHHHHHHHHT...-SHHHHCSHHHHHHHHHHHHHHHHHTTTT......... CS
         SLT   2 liikaekkygvepsllaaiaqvESgfnpkAvs...ksgavGLmQimpstakrlglrvk...lsedelldPeknisagakyLkslykqyng......... 85 
                 +i++ +++  v+ ++++ai+++ES++  +A     +++  GLmQ    t + +g +     + ++ lld +  +++g   L+sl+++y +         
  EEA19834.1 121 AIQQVARQTFVDHRFILAIIMQESKGCLRAPTtnwGVNNPGLMQDHGGTGTCYGVNPCpreSIVQMLLDGTSGTETGDG-LASLLDRYVTagedggmsq 218
                 57778888999***************999988778999******99999999887655776777888888888888843.4444444444444699988 PP

                 HHHHHHHHHHH-HH CS
         SLT  86 slllalaAYNaGeg 99 
                   ++a+ AYN+G  
  EEA19834.1 219 VFYKAARAYNSGSV 232
                 88999999999976 PP

>> STG  Simian taste bud-specific gene product family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.1      0.12   1.1e+03      53      76 ..      72      96 ..      59     130 .. 0.70
   2 ?   13.3   0.1   7.1e-06     0.064     133     200 ..     112     181 ..      88     198 .. 0.70

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.12
         STG 53 gsgvqkwppsegLps.mdsWpsedp 76
                gs    wp+s +  s +d W++ +p
  EEA19834.1 72 GSVAAGWPSSSQWVSfQDMWETSKP 96
                4555678887776652567877666 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 7.1e-06
         STG 133 dsesrrllrsnvLGaqgeilaqrPlwslinrirkpll..pghPWGtLnPsvsWGgGgpGtGWGtrpmpyp 200
                 d e  +l ++ +  a++  + +r + ++i +  k  l  p++ WG  nP++    Gg+Gt +G+ p p  
  EEA19834.1 112 DEEITNLHEAIQQVARQTFVDHRFILAIIMQESKGCLraPTTNWGVNNPGLMQDHGGTGTCYGVNPCPRE 181
                 445555555555555555555666666666666655544899************************9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (267 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       632  (0.0352502); expected 358.6 (0.02)
Passed bias filter:                      547  (0.0305092); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 1755.73
//
Query:       EEA19835.1  [L=868]
Description: exo-beta-1,3-glucanase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.6e-53  180.0  14.4      2e-45  155.3   4.5    2.6  3  Pectate_lyase_3  Pectate lyase superfamily protein
     0.0042   16.7   2.6       0.14   11.9   0.1    2.8  2  End_N_terminal   N terminal extension of bacteriophage endosi
     0.0094   16.1   1.0       0.16   12.1   0.4    2.3  2  DUF1080          Domain of Unknown Function (DUF1080)
  ------ inclusion threshold ------
      0.041   13.2   0.1      0.077   12.3   0.1    1.3  1  Lectin_leg-like  Legume-like lectin family
          4    7.5   8.1        7.7    6.6   8.1    1.4  1  Herpes_capsid    Gammaherpesvirus capsid protein


Domain annotation for each model (and alignments):
>> Pectate_lyase_3  Pectate lyase superfamily protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  155.3   4.5   5.6e-49     2e-45       1     215 []     160     378 ..     160     378 .. 0.97
   2 ?   -3.6   0.1       2.2   7.9e+03     136     155 ..     405     424 ..     388     446 .. 0.67
   3 !   31.5   0.4     4e-11   1.5e-07       9     203 ..     507     718 ..     496     730 .. 0.54

  Alignments for each domain:
  == domain 1  score: 155.3 bits;  conditional E-value: 5.6e-49
                      SEEGGGGT---EEEEE-HHHHHHHH...............HTSS-EEE-SEEEEESS-EEE-SSEEEEES-TTTEEEEE-TT-SS--SEEES-T CS
  Pectate_lyase_3   1 frnVkdyGakgDGvtDdtaaiqkais.........casatttgavVYfPaGtYlvsspiilksgvqLvGdgngrpvlkaaaafvgaglidgdpy 85 
                      +r+V +yGa++DG+ ++t a+q+ai+          +++t+ +a V++P G Y + +++ l+ g+ +vGd+ +rp++ka+++fvg++l++g++ 
       EEA19835.1 160 YRDVIEYGARNDGSGNQTEALQNAIDtdgmggsreGKGSTNMPAEVFLPGGVYTLGGTLTLRLGTIIVGDPLNRPIIKASPDFVGTSLVNGQDP 253
                      589********************************9*******************************************************999 PP

                      TT-..-EEEEEEEEEEEGGGG-SS---SSEEE..ES-EEEEEEEEEEES-SSEEE-SSS---TT---SS--EEEEES-EEES-SS-SEEES-EE CS
  Pectate_lyase_3  86 vsggsealiatnnfyrqirnlkiditavapga..tgihwqtaqatslenvefemseasgtkhqgifiengsggflndlvfsglgdigiavgnqq 177
                      +sg       + +f++ +rn++id+ta++p+   t+++w  aq+ sl nv+++m+++s + h gi ++ gs+  ++d++++g g+igi+ +nqq
       EEA19835.1 254 ASG-----HPETVFLVAMRNVIIDTTAIDPSItfTALQWGIAQGCSLGNVDINMPQGS-NGHIGIHLNGGSTIAVTDVTING-GGIGIQDSNQQ 340
                      977.....4678****************88887799**********************.9**********************.*********** PP

                      EEEES-EEE-S--SEEE-TT-EEEEEEEEEESSSEEEE CS
  Pectate_lyase_3 178 ftvrnitfnnattgievlwgwgwtlknvkinncegGid 215
                      ++++ni fn++ tg+ +  g +++l++ +++nc+ Gid
       EEA19835.1 341 VNFKNIRFNGCRTGFAATGGFTVVLQAATFENCGLGID 378
                      **********************************9996 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 2.2
                      EEE-SSS---TT---SS--E CS
  Pectate_lyase_3 136 emseasgtkhqgifiengsg 155
                      ++s++ g+ +++i+ien+++
       EEA19835.1 405 DSSNDPGNRNSQIVIENHNS 424
                      44555567777777777765 PP

  == domain 3  score: 31.5 bits;  conditional E-value: 4e-11
                      ---EEEEE-HHHHHHHH......HTSS-EEE-SEEEEESS-EEE-SSEEEEES-TTTEEEEE-TT-......SS--SEEES-TTT-.......- CS
  Pectate_lyase_3   9 akgDGvtDdtaaiqkaiscasatttgavVYfPaGtYlvsspiilksgvqLvGdgngrpvlkaaaaf......vgaglidgdpyvsg.gs....e 91 
                      +kgDGvtDd+  +++++   ++ ++ +v YfP G Yl++ ++ ++ g  +vG++   +vl +a+++       +  +     y ++ g+    +
       EEA19835.1 507 VKGDGVTDDSTSLNAIL--RDNAANCRVSYFPYGVYLLRDTLFIPPGSRIVGQA--WAVLSGAGGAftdpwnPRPVVR--VGYPGDvGVaeiqN 594
                      79***************..8888888899************************9..5555555544333332111111..12221121123334 PP

                      EEEEEEEEEEEGGGG-SS---SSEEE.....ES-EEEEEEEEEEES-SSEEE-SSS---TT---SS--E...EEE........ES-EEES-SS- CS
  Pectate_lyase_3  92 aliatnnfyrqirnlkiditavapga.....tgihwqtaqatslenvefemseasgtkhqgifiengsg...gfl........ndlvfsglgdi 169
                         +++ ++ +++ l i++ + +pg      t + +    +t+++n  ++ +     ++  +f++ + +   +++         d   +g g  
       EEA19835.1 595 MRFTVSEVLPGAKILEINMAGSSPGDvglwnTLTTVGGTADTTVSNSCVNQDA---RTCMAVFMHVHLSgtsSTYienhwgwtADHNLDG-GPS 684
                      55566777777888888888888888444433333444445555555333222...4466666544433222111221111123444444.444 PP

                      SEEE.S-EEEEEES-EEE-S--SEEE-TT-EEEEE CS
  Pectate_lyase_3 170 giav.gnqqftvrnitfnnattgievlwgwgwtlk 203
                      +i + g   + +++ + +    g++++ +w + ++
       EEA19835.1 685 AIIIaGGRGILIESTKATW-LVGTSFEHNWLYQYN 718
                      4444345555555555554.555555555554444 PP

>> End_N_terminal  N terminal extension of bacteriophage endosialidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.5     0.014        51       1      32 [.     168     199 ..     168     204 .. 0.92
   2 !   11.9   0.1   3.8e-05      0.14       2      25 ..     508     531 ..     507     534 .. 0.88

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.014
                     ---EEEEE-HHHHHHHHHHS-TTS-EE-TT-E CS
  End_N_terminal   1 akGDGvtdDtdalsevlaaapvgkkidGrGlt 32 
                     a  DG  + t+al++++ +   g   +G+G t
      EEA19835.1 168 ARNDGSGNQTEALQNAIDTDGMGGSREGKGST 199
                     567****************9999999***998 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 3.8e-05
                     --EEEEE-HHHHHHHHHHS-TTS- CS
  End_N_terminal   2 kGDGvtdDtdalsevlaaapvgkk 25 
                     kGDGvtdD  +l+++l + +++ +
      EEA19835.1 508 KGDGVTDDSTSLNAILRDNAANCR 531
                     8***************99888766 PP

>> DUF1080  Domain of Unknown Function (DUF1080)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.1   0.4   4.4e-05      0.16     139     184 ..     308     348 ..     298     349 .. 0.90
   2 ?    2.1   0.0     0.049   1.8e+02      40     129 ..     358     449 ..     348     451 .. 0.63

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 4.4e-05
                 TEEEEEETTEEEEEEETTSHHHHHHSSBEEEEECCCSTEEEEEEEE CS
     DUF1080 139 drvtvwlNGvlvldftdldaetekgkkgpIaLqdhgaeveFRniki 184
                  ++ + lNG  ++ +td +      + g I++qd +++v F+ni+ 
  EEA19835.1 308 GHIGIHLNGGSTIAVTDVTI-----NGGGIGIQDSNQQVNFKNIRF 348
                 5677889*************.....79*****************96 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.049
                 ESSS--EEESSEBSSEEEEEEEEEETTTEEEEEEEESCTTTSSGGGTSCEEEEE-TTTHSTCCCSTTSBTTT...........BTTB--SSS--S--TT CS
     DUF1080  40 gkgggflitkkefgdfeLklefkiseggnSGillrsqkeekgkdavagyevqildsekekganrstGslyde...........eskqvkpkakaakppg 127
                 ++g+++++ +  f+++ L +++  +++  S + l s+        ++g+ v+ +ds+++  + ++  +++ e            +++ + + +a++ +g
  EEA19835.1 358 TGGFTVVLQAATFENCGLGIDMT-KNSLGSMVVLDST------STNTGMLVKFHDSSND--PGNRNSQIVIEnhnsdgqfplaSTSDGRTVLNAQNHVG 447
                 56667777778999999999999.8888888888888......7778888888888877..33333333322233333333323334446666666666 PP

                 SE CS
     DUF1080 128 eW 129
                 +W
  EEA19835.1 448 TW 449
                 66 PP

>> Lectin_leg-like  Legume-like lectin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.1   2.1e-05     0.077      66     145 ..     360     438 ..     349     446 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 2.1e-05
                      EEEEESS--SS-S-EEEEEEESSSSSCCSBTTB-SS-EEEEEEEE-S-TSCTTTSS-SSEEEEEEEESSC---GGGTTTT CS
  Lectin_leg-like  66 sFrvtgseselegdglaiwytsergkegpvFgskdkfdGlailldtydndngpdkknkptisamlndgsleydhekdgka 145
                       F v+ +    e+ gl i  t+++     v  s+    G+ + +   +nd g  ++ +++i    +dg+++++ + dg++
       EEA19835.1 360 GFTVVLQAATFENCGLGIDMTKNSLGSMVVLDSTSTNTGMLVKFHDSSNDPGN-RNSQIVIENHNSDGQFPLASTSDGRT 438
                      6888888889999*****************************88777888876.7999*******************986 PP

>> Herpes_capsid  Gammaherpesvirus capsid protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   8.1    0.0021       7.7     106     166 ..      70     131 ..      37     133 .. 0.79

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.0021
  Herpes_capsid 106 taegttgGgsdssasGasGgsastls.SgpsssaaasglssgasStsdtasravadskapps 166
                     ++g t  +s s +s a+  +ast+  S +++s a    + ++sS sd+    + +++++p+
     EEA19835.1  70 LGPGVTFTTSRSRGSTAPAWAASTAMgSNNQGSMASTTHGVSSSSPSDVNYCVGNQQSQQPT 131
                    47888899999*9999999999886527778888999999999******9999999999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (868 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       316  (0.0176251); expected 358.6 (0.02)
Passed bias filter:                      205  (0.011434); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.64u 0.27s 00:00:00.91 Elapsed: 00:00:00.45
# Mc/sec: 5789.19
//
Query:       EEA19836.1  [L=377]
Description: sterol 24-c-methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      6e-30  103.4   0.8      1e-29  102.6   0.8    1.4  1  Sterol_MT_C      Sterol methyltransferase C-terminal
    9.1e-22   77.5   0.0    1.9e-21   76.5   0.0    1.6  1  Methyltransf_11  Methyltransferase domain
    9.7e-20   71.1   0.0    2.9e-19   69.6   0.0    1.8  1  Methyltransf_25  Methyltransferase domain
    2.3e-18   66.5   0.0    3.4e-18   65.9   0.0    1.3  1  Methyltransf_31  Methyltransferase domain
    2.6e-13   49.9   0.0    3.9e-13   49.3   0.0    1.2  1  CMAS             Mycolic acid cyclopropane synthetase
    6.4e-12   45.6   0.0    1.1e-11   44.9   0.0    1.4  1  Methyltransf_23  Methyltransferase domain
    2.5e-10   40.1   0.0    4.1e-10   39.4   0.0    1.2  1  Ubie_methyltran  ubiE/COQ5 methyltransferase family
    3.6e-09   37.3   0.0    9.3e-09   35.9   0.0    1.7  1  Methyltransf_12  Methyltransferase domain
      7e-06   24.9   0.0    9.4e-06   24.4   0.0    1.1  1  Methyltransf_29  Putative S-adenosyl-L-methionine-dependent m
    0.00066   19.5   0.0     0.0011   18.7   0.0    1.3  1  PCMT             Protein-L-isoaspartate(D-aspartate) O-methyl
     0.0018   17.6   0.0     0.0028   17.0   0.0    1.3  1  Methyltransf_2   O-methyltransferase domain
     0.0021   17.5   0.0     0.0042   16.5   0.0    1.4  1  PrmA             Ribosomal protein L11 methyltransferase (Prm
  ------ inclusion threshold ------
      0.017   14.8   0.0      0.026   14.1   0.0    1.3  1  MetW             Methionine biosynthesis protein MetW
      0.026   14.1   0.0       0.04   13.5   0.0    1.3  1  Methyltransf_15  RNA cap guanine-N2 methyltransferase
      0.033   13.7   0.0      0.065   12.8   0.0    1.4  1  MTS              Methyltransferase small domain
      0.047   13.4   0.0        0.1   12.3   0.0    1.7  1  UPF0020          Putative RNA methylase family UPF0020
      0.055   13.4   0.1      0.085   12.8   0.1    1.2  1  TSC21            TSC21 family
      0.062   13.3   0.6       0.18   11.8   0.0    1.9  2  Methyltransf_32  Methyltransferase domain
      0.085   12.3   0.0       0.17   11.3   0.0    1.5  1  TehB             Tellurite resistance protein TehB
       0.12   11.5   0.0       0.18   10.8   0.0    1.2  1  RrnaAD           Ribosomal RNA adenine dimethylase


Domain annotation for each model (and alignments):
>> Sterol_MT_C  Sterol methyltransferase C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.6   0.8   1.1e-32     1e-29       1      66 []     312     377 .]     312     377 .] 0.98

  Alignments for each domain:
  == domain 1  score: 102.6 bits;  conditional E-value: 1.1e-32
  Sterol_MT_C   1 ltvfrmtkvGrfithnlvkvleflglapkGtqkvaefLekAadsLvaGGkegiFTPmylfvaRKPl 66 
                  ltv+rmt++Gr ++h +++v+e+l+l+pkGtqk+a++L+ Aad+LvaGG++++FTPmyl+v+RKP+
   EEA19836.1 312 LTVLRMTRLGRGFMHRFMGVMEKLWLMPKGTQKTADSLALAADCLVAGGEKKLFTPMYLMVGRKPE 377
                  699**************************************************************6 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.5   0.0   2.1e-24   1.9e-21       1      94 [.     132     228 ..     132     230 .. 0.98

  Alignments for each domain:
  == domain 1  score: 76.5 bits;  conditional E-value: 2.1e-24
                      EEET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-..EEEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHHHEEEE CS
  Methyltransf_11   1 LdvGcGtGrlaealakrg.arvvgvDlskemlklakekaseegl..kvefvvadaeklpfednsfDlvvssevlhhvedpekalkeiaRvLkpg 91 
                      LdvGcG G  a+++ k +  +vvg++ +++++++a + a +egl  k++f+++d+ ++pf+dnsfD+v++ e+  h + +e + +ei RvLkpg
       EEA19836.1 132 LDVGCGVGGPAREIVKFAgVNVVGFNNNDYQIQRATRYAAQEGLsdKLTFQKGDFMQMPFPDNSFDAVYAIEATVHAPSLEGVYSEICRVLKPG 225
                      8**************9889*************************************************************************** PP

                      EEE CS
  Methyltransf_11  92 Gll 94 
                      G++
       EEA19836.1 226 GVF 228
                      *97 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.6   0.0   3.2e-22   2.9e-19       1      97 []     131     226 ..     131     226 .. 0.95

  Alignments for each domain:
  == domain 1  score: 69.6 bits;  conditional E-value: 3.2e-22
                      EEEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHHTTT..TEEEEESBCCGBSSSTTTEEEEEEESTGGGSSHHHHHHHHHHHHHH CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlgkakvtgvDiseemleaareraeeegl..nvefvqgdaedlpfedgsfDlvvssgalhhlsdedlekalkeiarv 92 
                      vLd+GcG G  ++++ k  g  +v+g+  ++ ++++a + a++egl  +++f++gd+ ++pf+d+sfD+v+++ a  h   + le +++ei+rv
       EEA19836.1 131 VLDVGCGVGGPAREIVKFAG-VNVVGFNNNDYQIQRATRYAAQEGLsdKLTFQKGDFMQMPFPDNSFDAVYAIEATVH--APSLEGVYSEICRV 221
                      9***************9987.***************************************************988444..5689********** PP

                      EEEEE CS
  Methyltransf_25  93 LkpgG 97 
                      LkpgG
       EEA19836.1 222 LKPGG 226
                      ****9 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.9   0.0   3.7e-21   3.4e-18       2     122 ..     126     243 ..     125     276 .. 0.87

  Alignments for each domain:
  == domain 1  score: 65.9 bits;  conditional E-value: 3.7e-21
  Methyltransf_31   2 dkglrvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielArenaqklgld.nveFeqgdieeleklledekfDlilsnevlnaladpdkil 94 
                      ++g++vlD+GCG G  + e+    + + +vvG+ ++   i++A+  a++ gl+  ++F++gd+ +++  + d++fD + + e+  + ++++ ++
       EEA19836.1 126 KEGMKVLDVGCGVGGPAREIV--KFAGVNVVGFNNNDYQIQRATRYAAQEGLSdKLTFQKGDFMQMP--FPDNSFDAVYAIEATVHAPSLEGVY 215
                      689******************..456799**********************999*************..************************* PP

  Methyltransf_31  95 eeiervlkpggilliedprllaelpakv 122
                       ei+rvlkpgg++ + +  + +e++   
       EEA19836.1 216 SEICRVLKPGGVFGVYEWLMTDEYDNDN 243
                      ************9876665555555444 PP

>> CMAS  Mycolic acid cyclopropane synthetase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.3   0.0   4.3e-16   3.9e-13      10     189 ..      78     253 ..      68     290 .. 0.77

  Alignments for each domain:
  == domain 1  score: 49.3 bits;  conditional E-value: 4.3e-16
                 HHHHHTS-HHHHCTTS-TT---S----SSTT--HHHHHHHHHHHHHTTTT--TT-EEEEES-TTSHHHHHHHHHH--EEEEEES-HHHHHHHHHHHHTS CS
        CMAS  10 ikahYDlsndffalfldptmtYsCAyferddmtLeeAqlaKldlileklelkpGmtlLdiGcGWGslvrraverydvkvvglTlSkeqaklakkrvdel 108
                  ++ Y l+ d+++   + +  + C  f + +  + +A  +  + + + ++lk+Gm++Ld+GcG G+ +r+ v+  +v+vvg    + q ++a +  +++
  EEA19836.1  78 TRHYYNLATDLYEYGWGSSFHF-C-RFAHGEP-FRQAIARHEHYLAHSMGLKEGMKVLDVGCGVGGPAREIVKFAGVNVVGFNNNDYQIQRATRYAAQE 173
                 5666788888888877777666.4.3444433.678888888889999*************************************************** PP

                 -SSS-EEEEES-GGG---...--SEEEEES-GGGTSGGGHHHHHHHHHHHS-TT-EEEEEEEEE--HHHHHCTTCCCHHHHHHT CS
        CMAS 109 dlerkvevklldyedlde...kvdrvvsvgafehvgkenydtffkklkkllkedGllllhtitslhkkelaerglklkfidkei 189
                 +l++k + +  d+ +++     +d+v +++a+ h    +++  ++++ ++lk++G++ +    ++++  + +++   + i+  i
  EEA19836.1 174 GLSDKLTFQKGDFMQMPFpdnSFDAVYAIEATVH--APSLEGVYSEICRVLKPGGVFGVYEWLMTDEYDNDNQEH--REIRLGI 253
                 ***************9653458999999998766..678999999************999888887776664442..3355555 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.9   0.0   1.2e-14   1.1e-11      20     163 ..     125     280 ..     102     282 .. 0.77

  Alignments for each domain:
  == domain 1  score: 44.9 bits;  conditional E-value: 1.2e-14
  Methyltransf_23  20 lraggrvLdiGcGtGillevlren.gfsvtgvDlspeaveiae.........kakkaqkdqfdeqeaaepqgkfdlIvlrevlehvpdppellr 103
                      l++g++vLd+GcG+G  ++++ ++ g++v+g+  ++ ++++a           + + qk  f  ++ ++p+++fd ++++e + h p+++ + +
       EEA19836.1 125 LKEGMKVLDVGCGVGGPAREIVKFaGVNVVGFNNNDYQIQRATryaaqeglsDKLTFQKGDF--MQMPFPDNSFDAVYAIEATVHAPSLEGVYS 216
                      78999**********888888666599***************99999999754444455555..8999************************** PP

  Methyltransf_23 104 qiatllkpgGylllseplaslkedrllld...wlylvpagrhi.sffsarslkelleeaGlevv 163
                       i + lkpgG++ + e+l  ++ d++ ++   +++  ++g+ i ++   ++  ++ ++aG+e++
       EEA19836.1 217 EICRVLKPGGVFGVYEWLMTDEYDNDNQEhreIRLGIEQGDGIsNMVKVSEGLDAIKAAGFELL 280
                      ***********99999887775555444433365555555333377777777777777777765 PP

>> Ubie_methyltran  ubiE/COQ5 methyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.4   0.0   4.6e-13   4.1e-10      38     153 ..     118     232 ..     110     239 .. 0.87

  Alignments for each domain:
  == domain 1  score: 39.4 bits;  conditional E-value: 4.6e-13
                      HHHHH--S--TTEEEEES-TT-HHHHHHHHHHHHHHEEEEEES-HHHHHHHHHHHHHHTSS.TEEEEE--TTT-TTS-T-EEEEEEES-GGG-S CS
  Ubie_methyltran  38 fveklvavkrgakvlDvagGtgDlafklsdsvgekgkvvvlDinenmLkvgekklkeegki.nieflqanaeeLpfeddsfDvvtvsfGlrnvt 130
                      ++ + ++ k+g kvlDv +G g  a ++ + +g   +vv+ + n+  ++ + + + +eg + ++ f +++ +++pf d+sfD v         +
       EEA19836.1 118 YLAHSMGLKEGMKVLDVGCGVGGPAREIVKFAGV--NVVGFNNNDYQIQRATRYAAQEGLSdKLTFQKGDFMQMPFPDNSFDAVYAIEATVHAP 209
                      56678999******************99999874..577888888888899999999999989*******************865555555689 PP

                      -HHHHHHHHHHHEEEEEEEEEEE CS
  Ubie_methyltran 131 DklkaLkeayrvlkpGGrlvvle 153
                        + +  e+ rvlkpGG + v e
       EEA19836.1 210 SLEGVYSEICRVLKPGGVFGVYE 232
                      999***************99887 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.9   0.0     1e-11   9.3e-09       1      99 []     132     228 ..     132     228 .. 0.92

  Alignments for each domain:
  == domain 1  score: 35.9 bits;  conditional E-value: 1e-11
  Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvelealdlldldgg.ssfDlvvasnvlhhlkdirevldnirklL 93 
                      L++GcG+G  +r++ +   +++++g   +  +i +++++ a++e++  +++++++ d  + + + +sfD+v+a+++  h + ++ v ++i ++L
       EEA19836.1 132 LDVGCGVGGPAREIVKF-AGVNVVGFNNNDYQI-QRATRYAAQEGL-SDKLTFQKGDFMQMPFPdNSFDAVYAIEATVHAPSLEGVYSEICRVL 222
                      8*************988.***************.778888887764.589*******99888779***************************** PP

  Methyltransf_12  94 kpgGrl 99 
                      kpgG++
       EEA19836.1 223 KPGGVF 228
                      ****86 PP

>> Methyltransf_29  Putative S-adenosyl-L-methionine-dependent methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4   0.0   1.1e-08   9.4e-06     117     223 ..     127     236 ..      94     255 .. 0.76

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 1.1e-08
  Methyltransf_29 117 kvrtvlDvGCgvasfgaylls.rdvltlslapkDeh.eaqvqfaLeRgvpailavlgt..krlpyPsrsfdlihCsrCridwteedgilllevd 206
                      +  +vlDvGCgv   +  +++  +v  + +  +D   +    +a   g+   l+      +++p+P +sfd +      ++  + +g++  e+ 
       EEA19836.1 127 EGMKVLDVGCGVGGPAREIVKfAGVNVVGFNNNDYQiQRATRYAAQEGLSDKLTFQKGdfMQMPFPDNSFDAVYAIEATVHAPSLEGVY-SEIC 219
                      44579*********9999998468999******9752566799******9988876432389*************************98.7*** PP

  Methyltransf_29 207 RvlRpgGyfvlsappvy 223
                      Rvl+pgG f +    ++
       EEA19836.1 220 RVLKPGGVFGVYEWLMT 236
                      *******8844333333 PP

>> PCMT  Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   1.2e-06    0.0011      69     156 ..     119     209 ..     108     230 .. 0.71

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 1.2e-06
                 TT....--TT-EEEEES-TTSHHHHHHHHHHCTTCEEEEEESBHHHHHHHHHHHHHCTTC.SEEEEES-GGGTTGGG-SEEEEEESSBBSS-- CS
        PCMT  69 le....lkkgarvLevGsGsGyltavlarlvgekgrvvsierikelveeakrnlkkldle.nvivvvgDGrkGyeekaPYdaihvgaaapeiP 156
                 l     lk+g++vL+vG+G G  +  + ++ g   +vv+ +     +++a+r   +++l+ +++++ gD  +   +   +da++   a+ + P
  EEA19836.1 119 LAhsmgLKEGMKVLDVGCGVGGPAREIVKFAGV--NVVGFNNNDYQIQRATRYAAQEGLSdKLTFQKGDFMQMPFPDNSFDAVYAIEATVHAP 209
                 444444***************998655555554..57****999999999999988888779*******987666666789887654444333 PP

>> Methyltransf_2  O-methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0   3.1e-06    0.0028      60     130 ..     125     198 ..      85     250 .. 0.81

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 3.1e-06
                     GGG-SEEEEET-TTSHHHHHHHHH-TT-EEEEEE-HH.HHHHHHHHS.-----TTEEEEES-TTTS---..--SE CS
  Methyltransf_2  60 leglkslvDvGGGtGalakaivsayPtikvivfDlpe.VveaAkehl.sageeervefvgGdffkdslP..eaDa 130
                     l++  +++DvG G+G  a++iv ++ +++v+ f   +  +++A ++  + g++++++f++Gdf++ + P  + Da
      EEA19836.1 125 LKEGMKVLDVGCGVGGPAREIV-KFAGVNVVGFNNNDyQIQRATRYAaQEGLSDKLTFQKGDFMQMPFPdnSFDA 198
                     77777899*************8.599*****9998762599999998788999***********99999433455 PP

>> PrmA  Ribosomal protein L11 methyltransferase (PrmA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   4.6e-06    0.0042     159     257 ..     125     229 ..     116     240 .. 0.88

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 4.6e-06
        PrmA 159 vkegeevlDvGtGSGiLaiaaakLgakkvvavDiDevAvkvakeNaelNkveaklevalseellk....eekadviv...aNILaevlielaedikklv 250
                 +keg +vlDvG+G G  a   +k++  +vv+   ++  ++ a + a++ ++++kl+ +++++ ++    ++++d +    a + a  l   +++i++++
  EEA19836.1 125 LKEGMKVLDVGCGVGGPAREIVKFAGVNVVGFNNNDYQIQRATRYAAQEGLSDKLT-FQKGDFMQmpfpDNSFDAVYaieATVHAPSLEGVYSEICRVL 222
                 78999**************************************************5.577888866777788887762226899999************ PP

        PrmA 251 kegglli 257
                 k+gg++ 
  EEA19836.1 223 KPGGVFG 229
                 ****985 PP

>> MetW  Methionine biosynthesis protein MetW
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   2.9e-05     0.026      11      84 ..     125     204 ..     114     225 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 2.9e-05
        MetW  11 ikpgsrvldlGcGdGellellkeekqvdgrGleldeegvaecv....akGls..viqgdldkdlenfedksfdyvvlsqt 84 
                 +k+g +vld+GcG G   + + +  +v+  G ++++  +++++    + Gls  +  +  d     f+d+sfd v    +
  EEA19836.1 125 LKEGMKVLDVGCGVGGPAREIVKFAGVNVVGFNNNDYQIQRATryaaQEGLSdkLTFQKGDFMQMPFPDNSFDAVYAIEA 204
                 67899*********9999999999***********99999865333378997224445555556779******9864443 PP

>> Methyltransf_15  RNA cap guanine-N2 methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   4.5e-05      0.04       3      60 ..     130     188 ..     128     246 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 4.5e-05
  Methyltransf_15   3 vilDlfsGaGGnviqfalv.fekviaieinleklacaqhNaevYgvsdkitlvlgdvfe 60 
                       +lD+ +G GG + ++ +  + +v++ + n  +++ a++ a   g sdk+t+ +gd+++
       EEA19836.1 130 KVLDVGCGVGGPAREIVKFaGVNVVGFNNNDYQIQRATRYAAQEGLSDKLTFQKGDFMQ 188
                      58*********8877655435679999******************************98 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   7.3e-05     0.065      26     101 ..     122     199 ..     116     202 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 7.3e-05
                 HCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTT.STTS-EEEE CS
         MTS  26 tlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvlee.veekkfdli 101
                  +  ++  kvlD+GcG+G  + ++ k+    +v+ ++++ + ++ a++ +++++l+  +++ + d ++  +++++fd++
  EEA19836.1 122 SMGLKEGMKVLDVGCGVGGPAREIVKFAGV-NVVGFNNNDYQIQRATRYAAQEGLSdkLTFQKGDFMQMpFPDNSFDAV 199
                 555556789****************98776.788888888889999888888888878889999988751458888876 PP

>> UPF0020  Putative RNA methylase family UPF0020
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   0.00011       0.1      77     125 ..     151     199 ..     102     225 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00011
                 --EEEEES-HHHHHHHHHHHHHTT-GGGEEEEE--GGG--STTS---EE CS
     UPF0020  77 lklygsDldrrvvqgareNaekagvgdliefsqadaakLrlkegevdvi 125
                 ++++g++++   +q+a + a + g++d+ +f++ d+ +++ +++++d++
  EEA19836.1 151 VNVVGFNNNDYQIQRATRYAAQEGLSDKLTFQKGDFMQMPFPDNSFDAV 199
                 4599************************************9999**988 PP

>> TSC21  TSC21 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.1   9.5e-05     0.085      45     116 ..       9      80 ..       2     117 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 9.5e-05
       TSC21  45 dtqlrekefyrpipspnpkledGypafkrpymtardlGlpGffppqdrvataedearftsicpsvypaskal 116
                 ++  r+ +f +++  +  ++e G++a++ +   a++l +  +f   d++a+ae+ +     ++  y++ +  
  EEA19836.1   9 ENHQRDADFNKAMHGKSSQIEGGWSAMRAKDNKAQQLAVDEYFKHWDNKAAAEETEATREARRAEYATLTRH 80 
                 45678999*******************************************999988888888888765443 PP

>> Methyltransf_32  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.4       1.7   1.5e+03      65     104 ..       8      58 ..       3      84 .. 0.49
   2 ?   11.8   0.0    0.0002      0.18      24      93 ..     126     190 ..     109     250 .. 0.85

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 1.7
  Methyltransf_32  65 ekaekraeklgkkfnkrlsfaelsieeatssktltkkve...........a 104
                      +++ +r++ ++k+++ + s++e+  +   +++ + +++            a
       EEA19836.1   8 QENHQRDADFNKAMHGKSSQIEGGWSAMRAKDNKAQQLAvdeyfkhwdnkA 58 
                      445555555555555555555444444433333333222445554443331 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 0.0002
  Methyltransf_32  24 sgaltvvDvGaGkgYLsfvlalkekeyklkvvgidakeelvekaekraeklgkkfnkrlsfaelsieeat 93 
                      ++ ++v+DvG+G g  ++ +       +++vvg++ ++  +++a + a++ g  ++++l f++++  +  
       EEA19836.1 126 KEGMKVLDVGCGVGGPAREIVK---FAGVNVVGFNNNDYQIQRATRYAAQEG--LSDKLTFQKGDFMQMP 190
                      56789*********99998888...78***********************99..9999999999877765 PP

>> TehB  Tellurite resistance protein TehB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00019      0.17      31      79 ..     128     177 ..     111     240 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00019
                 S-EEEEES-TTSHHH.HHHHHTT-EEEEEES-HHHHHHHHHHHHHTT-TT CS
        TehB  31 pgkvldlgcgqgrns.lylsllgydvtawdknensiafleeikekenlkn 79 
                   kvld+gcg g  +   ++  g +v  +++n+  i+   + + +e l++
  EEA19836.1 128 GMKVLDVGCGVGGPArEIVKFAGVNVVGFNNNDYQIQRATRYAAQEGLSD 177
                 579*******987651578999****************999999999864 PP

>> RrnaAD  Ribosomal RNA adenine dimethylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0    0.0002      0.18      27      94 ..     124     195 ..     116     220 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.0002
                 -GGTTSEEEEES-TTTCCHHHHHCC-.SEEEEE-.S-HHHHHHHHCHTT..TCCCEEEE-S-CCGHHHHHHH CS
      RrnaAD  27 nleekltvleigpGkGilTeeLakra.kqvvvlE.lderLakllqkkls..kdeklkvvhqDflkfetpeev 94 
                  l+e ++vl++g G+G   +e++k a  +vv +  +d ++   ++ + +  ++ kl+  + Df+++ +p + 
  EEA19836.1 124 GLKEGMKVLDVGCGVGGPAREIVKFAgVNVVGFNnNDYQIQRATRYAAQegLSDKLTFQKGDFMQMPFPDNS 195
                 689***********************9788777615666666666655578999***********9999865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (377 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       649  (0.0361983); expected 358.6 (0.02)
Passed bias filter:                      483  (0.0269396); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              20  [number of targets reported over threshold]
# CPU time: 0.59u 0.30s 00:00:00.88 Elapsed: 00:00:00.51
# Mc/sec: 2240.77
//
Query:       EEA19837.1  [L=386]
Description: pre-RNA splicing factor Slt11, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.4e-08   33.7   0.0    4.1e-08   32.9   0.0    1.4  1  RRM_1            RNA recognition motif. (a.k.a. RRM, RBD, or 
    0.00029   20.6   0.0    0.00049   19.9   0.0    1.3  1  RRM_occluded     Occluded RNA-recognition motif
    0.00041   20.3   0.0    0.00068   19.6   0.0    1.3  1  Nup35_RRM_2      Nup53/35/40-type RNA recognition motif
  ------ inclusion threshold ------
        1.5    9.4  12.0        0.6   10.7   5.1    2.5  2  FoP_duplication  C-terminal duplication domain of Friend of P


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.9   0.0   9.2e-12   4.1e-08       1      69 [.     247     311 ..     247     312 .. 0.90

  Alignments for each domain:
  == domain 1  score: 32.9 bits;  conditional E-value: 9.2e-12
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTT.EEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealng.kklggrel 69 
                 lf++++  d+ e+e++++F++fG+ +s+  ++        +afV+++++ +Ae+A  +++g   ++g++l
  EEA19837.1 247 LFITGVEDDLPEHEVRTFFEQFGQLRSLICSH-----RAHCAFVNYATRASAEAAALQCQGkAIIKGCPL 311
                 89***********************6666666.....7***********************778888876 PP

>> RRM_occluded  Occluded RNA-recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   0.0   1.1e-07   0.00049       4      70 ..     247     313 ..     244     321 .. 0.91

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 1.1e-07
  RRM_occluded   4 isllplsDtvnkariralveekegeikkivLvpdheGAivefkdekiagkasLaLdgsef.egkklrc 70 
                   + + ++ D   + ++r+++e+  g+++ +++    ++A+v ++ +++a  a+L+ +g+ + +g  lr+
    EEA19837.1 247 LFITGVEDDLPEHEVRTFFEQF-GQLRSLICSHRAHCAFVNYATRASAEAAALQCQGKAIiKGCPLRV 313
                   5577899***************.**********************************99746877765 PP

>> Nup35_RRM_2  Nup53/35/40-type RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.0   1.5e-07   0.00068       5      52 ..     248     296 ..     245     297 .. 0.92

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 1.5e-07
  Nup35_RRM_2   5 aVsGydteli.elVlehFasfGeIvkhyvpkevsvmyvkfesekdaekA 52 
                   ++G++ +l   +V+ +F++fG+     ++ + + ++v ++++ +ae A
   EEA19837.1 248 FITGVEDDLPeHEVRTFFEQFGQLRSLICSHRAHCAFVNYATRASAEAA 296
                  6899999997689*********************************988 PP

>> FoP_duplication  C-terminal duplication domain of Friend of PRMT1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   5.1   0.00013       0.6      13      43 ..     196     227 ..     180     237 .. 0.62
   2 ?    2.5   0.6     0.049   2.2e+02      15      40 ..     328     353 ..     319     368 .. 0.54

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00013
  FoP_duplication  13 grggrrgrgrggrggrggrgrgrggrgg.rkk 43 
                      + ++r++ ++g+ g++ggrg+grggr+   ++
       EEA19837.1 196 SDSRRGAPFNGRGGRGGGRGGGRGGRAFpPTT 227
                      34455555666666667777777777654444 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.049
  FoP_duplication  15 ggrrgrgrggrggrggrgrgrggrgg 40 
                       ++r+ + g++    +r++g+g+r+ 
       EEA19837.1 328 ERKRNAREGRQLVPPSRSGGQGQRAI 353
                      33444444444445566666666554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (386 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       995  (0.0554967); expected 358.6 (0.02)
Passed bias filter:                      516  (0.0287802); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.41
# Mc/sec: 2800.87
//
Query:       EEA19838.1  [L=113]
Description: mitochondrial complex I protein Fmp36, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.5e-06   26.6   1.9    5.6e-06   26.3   0.4    1.8  2  Complex1_LYR    Complex 1 protein (LYR family)
     0.0019   18.2   0.1     0.0024   17.9   0.1    1.2  1  MOSC            MOSC domain
  ------ inclusion threshold ------
       0.16   12.7   1.4       0.21   12.3   1.4    1.4  1  Complex1_LYR_2  Complex1_LYR-like


Domain annotation for each model (and alignments):
>> Complex1_LYR  Complex 1 protein (LYR family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.3   0.4   9.4e-10   5.6e-06       3      53 ..       8      62 ..       6      63 .. 0.83
   2 ?   -1.0   0.0      0.31   1.9e+03      23      46 ..      80     101 ..      67     111 .. 0.68

  Alignments for each domain:
  == domain 1  score: 26.3 bits;  conditional E-value: 9.4e-10
  Complex1_LYR  3 vLsLYRalLRearkfpdyntreyf..rrriRdeFrknkh..vtDpekieellkkg 53
                  ++s YR+lLR++r   ++++r  +  r+++R++F ++k   v  p +i+++l+ +
    EEA19838.1  8 AISAYRQLLRATRIAFKDDYRILLaaRSEARKQFNAHKRtaVDTPMQIQHALETA 62
                  7899********76666665555555************************99865 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.31
  Complex1_LYR  23 reyfrrriRdeFrknkhvtDpeki 46 
                    + +  ri de ++  +  D +ki
    EEA19838.1  80 DAKWELRIHDEIERGDN--DSVKI 101
                   45666677777766554..55555 PP

>> MOSC  MOSC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.1   3.9e-07    0.0024       2      71 ..      19      95 ..      18     113 .] 0.75

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 3.9e-07
                XX---GGGGSEEEEETHHHHHHHHHS..GGG.........GG-STTTT--SEEES-.......-TTT-BTT-E.EEETT CS
        MOSC  2 rkihggdekavllisresldalneelkegrs.........veldpgrfreNivvggaaafeEdtwkelrigdrrfrlgg 71
                ++i ++d+  +ll++r++ ++  +  k +++         +   ++ +r Niv g+ +a++Ed   elri+d+ ++ g+
  EEA19838.1 19 TRIAFKDDYRILLAARSEARKQFNAHK-RTAvdtpmqiqhALETASILRHNIVQGIRDAEKEDAKWELRIHDE-IERGD 95
                6899**********9999988733332.2224667779986677789***********************998.55444 PP

>> Complex1_LYR_2  Complex1_LYR-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   1.4   3.6e-05      0.21       2      47 ..       9      59 ..       8     100 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 3.6e-05
  Complex1_LYR_2  2 lsLYrrllrelrel.ppelr..slgdayvraefrrhk........hlknpeeialfl 47
                    +s Yr+llr+ r   + + r   + +   r++f++hk        +      i+  l
      EEA19838.1  9 ISAYRQLLRATRIAfKDDYRilLAARSEARKQFNAHKrtavdtpmQ------IQHAL 59
                    799********975444444778999999999***99554444443......54443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (113 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       481  (0.026828); expected 358.6 (0.02)
Passed bias filter:                      300  (0.0167327); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.41u 0.25s 00:00:00.65 Elapsed: 00:00:00.43
# Mc/sec: 797.46
//
Query:       EEA19839.1  [L=444]
Description: ribosome associated DnaJ chaperone Zuotin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.6e-30  106.0   9.2    1.6e-30  106.0   9.2    3.3  3  RAC_head    Ribosome-associated complex head domain
    1.4e-18   66.7   3.9    2.2e-18   66.1   1.9    2.5  2  DnaJ        DnaJ domain
  ------ inclusion threshold ------
        0.8    9.6   5.9        1.7    8.5   5.9    1.5  1  CemA        CemA family


Domain annotation for each model (and alignments):
>> RAC_head  Ribosome-associated complex head domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.2         3   1.8e+04      74      82 ..     117     125 ..     110     138 .. 0.49
   2 ?  -12.8  15.0         3   1.8e+04      12      18 ..     317     323 ..     253     341 .. 0.65
   3 !  106.0   9.2   2.7e-34   1.6e-30       1      97 [.     344     441 ..     344     442 .. 0.95

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 3
                 HHHHHHHHH CS
    RAC_head  74 vkavfkeev 82 
                 +k++  ++v
  EEA19839.1 117 IKRAHRKKV 125
                 333333333 PP

  == domain 2  score: -12.8 bits;  conditional E-value: 3
                 HHHHHHH CS
    RAC_head  12 KKekral 18 
                  Kek +l
  EEA19839.1 317 EKEKAKL 323
                 2222222 PP

  == domain 3  score: 106.0 bits;  conditional E-value: 2.7e-34
                 XXXXXXXX-HHHHHHHHHHHHHHHTGGGSSSS--.HHHHHHHHHHHHHHHHH--HHHHHHHHHHHTT-.--HHHHHHHHHHHHHHHHHTTSS-GGG-- CS
    RAC_head   1 KKaKeaaKkalKKekralrgavkdanYFadgeaekakvidkvLedvdllieklddeeLaelaekleaa.kdaeevkavfkeevkelveagklkeeklk 97 
                 KK KeaaK+a+KK+kr+lr++vkd+nYFa+g  ++a+++d+vL+dvd++++k+++eeLa+la+kl+ a +da++vka++ ee+k+l+++gklke+++k
  EEA19839.1 344 KKSKEAAKNAAKKNKRVLRNSVKDVNYFAEGGDASAAQVDNVLNDVDAIMAKISLEELATLAAKLTTAgTDAAAVKAAYVEEAKRLIGEGKLKEAEIK 441
                 9***************************77777779999***************************9956************************9987 PP

>> DnaJ  DnaJ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.1   1.9   3.6e-22   2.2e-18       1      63 []      98     166 ..      98     166 .. 0.91
   2 ?   -2.9   0.0       1.3   7.9e+03      13      26 ..     414     427 ..     410     429 .. 0.75

  Alignments for each domain:
  == domain 1  score: 66.1 bits;  conditional E-value: 3.6e-22
                 HHHHHHTSSTT...G-HHHHHHHHHHHHHHHSTTTS..CCHH.HHHHHHHHHHHHHHHHTSHHHHHHHH CS
        DnaJ   1 dyYeiLgvskd...asedeIkkaYrklalkyHPDkn..pkdp.eaeekFkeineAyevLsdpekRkqYD 63 
                 d+Y++Lg+sk    a++++Ik+a+rk++l++HPDk+  ++++ e++  Fk+i++A+e+L dp+kR+qYD
  EEA19839.1  98 DHYAVLGLSKYrykATSEQIKRAHRKKVLRHHPDKKaaAGQSdENDSFFKCIQKATEILLDPTKRRQYD 166
                 89********98889*******************8855444468888*********************9 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.3
                 -HHHHHHHHHHHHH CS
        DnaJ  13 sedeIkkaYrklal 26 
                 +++ +k+aY + a+
  EEA19839.1 414 DAAAVKAAYVEEAK 427
                 66789999998876 PP

>> CemA  CemA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   5.9   0.00029       1.7      35     117 ..     289     371 ..     272     374 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00029
        CemA  35 vdrflekeqaelflnkeleeealeelkefeekleleeligeapelseeeieeelkekaeelakeyreesseaiknifadlvsl 117
                 +++f++ ++a    ++  +e   ++++e++ek +lee  +++++ +  + e+e ++k +e ak++ +++++ ++n + d+ ++
  EEA19839.1 289 IKKFRQAKRAGKDKKRLEKEAEAKRIAEEKEKAKLEEERKKKEAEEAAKAEREANKKSKEAAKNAAKKNKRVLRNSVKDVNYF 371
                 5667755555555555556666899***************************************************9998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (444 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2884  (0.160857); expected 358.6 (0.02)
Passed bias filter:                      593  (0.0330749); expected 358.6 (0.02)
Passed Vit filter:                       164  (0.00914719); expected 17.9 (0.001)
Passed Fwd filter:                        41  (0.0022868); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 1.02u 0.38s 00:00:01.40 Elapsed: 00:00:00.54
# Mc/sec: 2494.52
//
Query:       EEA19840.1  [L=379]
Description: aryl-alcohol dehydrogenase Aad14, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.1e-69  233.4   0.0    3.5e-69  233.2   0.0    1.0  1  Aldo_ket_red  Aldo/keto reductase family
  ------ inclusion threshold ------
      0.093   12.4   0.0       0.25   11.0   0.0    1.7  1  Phage_tail_X  Phage Tail Protein X


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  233.2   0.0     4e-73   3.5e-69       1     293 [.      26     337 ..      26     338 .. 0.97

  Alignments for each domain:
  == domain 1  score: 233.2 bits;  conditional E-value: 4e-73
                   .EEEE-SSS-ST......TS-HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH-TTTGGG-EEEEEE.........--SSSTTSSSS-H CS
  Aldo_ket_red   1 elglGtwqlgsk.....eeiskeealellrraleaGinffDtAevYgkgqseellGealkksrkkreeviiatKv.........dlrdaeiksglsk 83 
                   +l+lG++++g+      + ++ke +++ll+ ++eaG nf+Dt++ Y++ qse+++G ++ + rk+r++++iatK          ++++ ++++g s+
    EEA19840.1  26 PLVLGGMSIGDAwaggmGSMDKEASFKLLDCYFEAGGNFIDTSNNYQDEQSEQWIGDWMTA-RKNRDQLVIATKYttgyknyelGKGKTPNHVGNSR 121
                   699*******99*************************************************.*********************************** PP

                   HHHHHHHHHHHHHHT-S-EEEEEE-S--TTS-.HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHH....HHTTT--EEEEE-B-BTT-HHHHTTHH CS
  Aldo_ket_red  84 eniresleeslkrLgtdyvDllllHrpdpslpsieevldaleelvkeGkiraiGvSnfsveqleka....kkkkkvkivavqveynllreleeegll 176
                    +++ s+++slk+L+tdy+D+l+lH+ d  ++ +ee++d l+ lv++Gk+ ++G+S  +++ ++++    ++++k++++++q ++n++ +++e++++
    EEA19840.1 122 RSLHMSVRDSLKKLQTDYIDILYLHWYDQLTS-VEEIMDSLHILVEQGKVLYLGISDSPAWLVSACnyyaRAHGKTPFSIYQGRWNVMLRDFEREII 217
                   ********************************.**************************************************************** PP

                   HHHHHTT-EEEEBSTTGGGTTGTTTSS---SSSCCC-------..TS-HHHHHHHHHHHHHHHHTT-.-HHHHHHHHHTTSTT-SEEEE--SSHHHH CS
  Aldo_ket_red 177 elckkkgvpliaysplggGlltgkyqseedkedkeprkdlkrd..ertsknldaaeelselakehgv.slaqlalryalsqpavgivipgasnieql 270
                   ++++  g++l ++ +lggG +++++  ee+k ++e  + l  +  e+ +k+ +  e+l ++a+eh+  s++++al+y++s+ +++++i+g ++ie+l
    EEA19840.1 218 PMARYFGMALAPWDVLGGGKFQSRKALEERKSQGEGLRTLFGSsgEQSEKETKISEALAKVAEEHNTdSVQAIALAYVMSKAPRVFPIVGGRKIEHL 314
                   **********************999999999887776665444799******************9999***************************** PP

                   HHHHGGGG----HHHHHHHHHHH CS
  Aldo_ket_red 271 ednldalelklseeevaeldell 293
                   + n++al++kl+++++++l++++
    EEA19840.1 315 KSNIEALKIKLTPQQIEQLESVV 337
                   *******************9975 PP

>> Phage_tail_X  Phage Tail Protein X
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   2.8e-05      0.25       6      47 ..     135     175 ..     131     176 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 2.8e-05
                   -TT-SHHHHHHHTTS--TTTHHHHHHHSTTTTTT-S---TTE CS
  Phage_tail_X   6 tqgdtlDalcwryYGrtlgvveavleaNPgLAelgpvLphGt 47 
                    q d +D l +++Y ++++v e++++  + L e g vL  G+
    EEA19840.1 135 LQTDYIDILYLHWYDQLTSV-EEIMDSLHILVEQGKVLYLGI 175
                   599*************9999.*****************9997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (379 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       606  (0.0338); expected 358.6 (0.02)
Passed bias filter:                      536  (0.0298957); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.48
# Mc/sec: 2393.10
//
Query:       EEA19841.1  [L=538]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (538 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       445  (0.0248201); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.48
# Mc/sec: 3344.10
//
Query:       EEA19842.1  [L=1850]
Description: DEAD/DEAH box helicase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.5e-16   60.6   0.0    8.3e-16   58.2   0.0    2.1  2  DEAD        DEAD/DEAH box helicase
    1.2e-10   41.7   0.0    3.8e-10   40.0   0.0    1.9  1  ResIII      Type III restriction enzyme, res subunit
    8.3e-07   29.3   0.0    2.9e-06   27.6   0.0    2.0  1  Helicase_C  Helicase conserved C-terminal domain
  ------ inclusion threshold ------
      0.042   13.3   0.0      0.082   12.3   0.0    1.4  1  PhoH        PhoH-like protein
       0.11   12.4   0.2       0.77    9.6   0.0    2.3  2  GH115_C     Gylcosyl hydrolase family 115 C-terminal domain
       0.91    9.3   7.9        2.1    8.1   7.9    1.6  1  AChE_tetra  Acetylcholinesterase tetramerisation domain
        2.1    8.5   4.4         19    5.3   3.4    2.8  2  TFR_dimer   Transferrin receptor-like dimerisation domain


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.2   0.0   3.2e-19   8.3e-16       3     170 ..     787     947 ..     785     952 .. 0.79
   2 ?   -1.2   0.0      0.59   1.5e+03     118     135 ..     997    1014 ..     978    1034 .. 0.83

  Alignments for each domain:
  == domain 1  score: 58.2 bits;  conditional E-value: 3.2e-19
                 HHHHHHHHHHTTCEEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTST...SEEEEEETTSSHHHHHHHHHTTC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   3 iQaeaiplilgggdvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyid...lrvlliiggvaardqlskldngv 98 
                  Q+ ++++i ++++ ++ a+T +GKT + + ++ qi+   k+++    ++v+Pt++L++q++ ++  ++++      +++++   +++++ +++   ++
  EEA19842.1 787 WQRDVLDQIDQKKSTFIVAPTSAGKTFISFYAMKQIL---KEDDDGVLVYVAPTKALVNQIAAEVMARFSKSYpenATAKSVWAIHTRDHRINNP-LTC 881
                 5999******************************999...678888*****************99888885321222222333333333333333.46* PP

                 SEEEEEHHHHHHHH...HCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBS CS
                 xxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  99 divvgtpgrlddll...stgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlp 170
                 +i+++ p  l+ +l   s+ +  + +++ +++DE++++ + + +  ++++l   p      +    +i+lSAT+ 
  EEA19842.1 882 QILITVPHILQIMLlapSNANTWTPRLKRIIFDEIHCIGQAEDGIVWEQLLLLAP-----CP----IIALSATVG 947
                 ************8878755555699999*************99999999777773.....33....9*****985 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.59
                  HCTTEEEEEEETHHHHHH CS
                  xxxxxxxxxxxxxxxxxx RF
        DEAD  118 nlsqvrflVlDEadrlld 135 
                  +ls ++ l lDEad++  
  EEA19842.1  997 KLSGLSHLGLDEADGMEL 1014
                  599999999******975 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.0   0.0   1.5e-13   3.8e-10      14     169 ..     790     946 ..     781     948 .. 0.75

  Alignments for each domain:
  == domain 1  score: 40.0 bits;  conditional E-value: 1.5e-13
                 HHT......TTSEEEEEESTTSTHHHHHHHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG.......GEEEESSS-B--.......-SEEEE CS
      ResIII  14 nlleklkskrdkrglikmaTGtGKTlvaaklierllkkgkeekflflvprkslleqtleefkkflseayke...igkkvsgdkkkakekdstnkkilvt 109
                 ++l+++  +++k  +i+++T +GKT++++ +++++lk+ +    + ++p+k+l++q   e++  +s+ y e   ++ ++   +++++ ++  +++il+t
  EEA19842.1 790 DVLDQI--DQKKSTFIVAPTSAGKTFISFYAMKQILKEDDDGVLVYVAPTKALVNQIAAEVMARFSKSYPEnatAKSVWAIHTRDHRINNPLTCQILIT 886
                 444555..599999***********************999989999************88777777776665654444444444443346778888888 PP

                 EHHHHHHTH........HHHTTT-S......EEEEETGGGTTS.T...TTHHHHHT---SEEEEEESS- CS
      ResIII 110 tiqsldadseeeeeeseellrdrfd......viiiDEaHrlgakk...swreilekfkeavllglTATp 169
                   + l+  +         + ++++        ii+DE H +g+++    w+++l    ++ +++l+AT 
  EEA19842.1 887 VPHILQIML--------LAPSNANTwtprlkRIIFDEIHCIGQAEdgiVWEQLLLL-APCPIIALSATV 946
                 888888777........223333223345569**********975788****6555.7899*******6 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.6   0.0   1.1e-09   2.9e-06      27     111 .]    1278    1363 ..    1259    1363 .. 0.83

  Alignments for each domain:
  == domain 1  score: 27.6 bits;  conditional E-value: 1.1e-09
                  HHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSS.HHHHHHHHTTSSSTT CS
  Helicase_C   27 drlekvklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprn.vtsyiqriGRtgRag 111 
                  +r e+ k+l    +  + v+h+ ++ + r+     f+kg  +v+iat  ++ Gi++p+ ++V+  d  +    ++ q++GR+gR g
  EEA19842.1 1278 KRREMPKWLIDALERGIGVHHAGMNRKYRQICEVLFRKGFLRVVIATGTLALGINMPCKTVVFSGDSVFLtALNFRQAAGRAGRRG 1363
                  4444456665555788999***********************************************9965379***********75 PP

>> PhoH  PhoH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   3.2e-05     0.082       8      58 ..     787     837 ..     783     847 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 3.2e-05
                 HHHHHHHHHHH-SEEEEE--TTSSTTHHHHHHHHHHHHTTS-SEEEEEE-S CS
        PhoH   8 eQkeylealkkndivfaiGpaGtGKtylavalavealkkkkvkriiltrpa 58 
                  Q+++l+++++++ +f+++p+ +GKt+++  +  ++lk+++   ++++ p+
  EEA19842.1 787 WQRDVLDQIDQKKSTFIVAPTSAGKTFISFYAMKQILKEDDDGVLVYVAPT 837
                 599**************************9888888888777777777665 PP

>> GH115_C  Gylcosyl hydrolase family 115 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.0    0.0003      0.77     102     149 ..     771     821 ..     762     823 .. 0.88
   2 ?   -2.0   1.4       1.1   2.9e+03     107     139 ..    1187    1220 ..    1161    1222 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0003
                 EETTTT-.....-HHHHHHHHHHS-EEEEEEEEE...-SEEEEEEEEE-ST CS
     GH115_C 102 vdlvpde.eagslpegWekavadnvrkrttevtv..lkpGkhtLkiwavdp 149
                 +d  pd+ +++ +p+ W++ v+d++ ++++++ v  +++Gk  + ++a+++
  EEA19842.1 771 IDSLPDPrTPDFNPDRWQRDVLDQIDQKKSTFIVapTSAGKTFISFYAMKQ 821
                 5666666678899*******************9999**********99875 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.1
                  T-.....-HHHHHHHHHHS-EEEEEEEEE.-SEE CS
     GH115_C  107 de.eagslpegWekavadnvrkrttevtvlkpGk 139 
                   + +++s+ ++W+++  ++ ++++ + t  ++G+
  EEA19842.1 1187 TSsKWKSDMDKWNEWRKQESKTKNQKTTKATKGQ 1220
                  2236788999999999999999999999988887 PP

>> AChE_tetra  Acetylcholinesterase tetramerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   7.9   0.00083       2.1       2      23 ..    1179    1200 ..    1178    1211 .. 0.87

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00083
  AChE_tetra    2 EaEqeWkaefhRWssyMmdWkn 23  
                  EaE++Wka    W+s M++W+ 
  EEA19842.1 1179 EAEKNWKATSSKWKSDMDKWNE 1200
                  9*******************75 PP

>> TFR_dimer  Transferrin receptor-like dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.0      0.27     7e+02      18      60 ..     950     986 ..     941     994 .. 0.76
   2 ?    5.3   3.4    0.0076        19       3      40 ..    1174    1211 ..    1173    1219 .. 0.75

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.27
   TFR_dimer  18 eefdkwadkwedvggaessllavrkrrkiNdklmrferafldp 60 
                 +ef++w ++ +      ++  +  k+ ++N++++++ +   +p
  EEA19842.1 950 NEFNSWLQRAQ-----DTNGHDL-KMIQYNHRYSDLRKYVYHP 986
                 79999999988.....4445555.4569******998876665 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0076
   TFR_dimer    3 ldpLeeaikkfkkaaeefdkwadkwedvggaessllav 40  
                  l++L+ea k++k +++++++ +dkw+++ + es+ +++
  EEA19842.1 1174 LTQLQEAEKNWKATSSKWKSDMDKWNEWRKQESKTKNQ 1211
                  6899**********************853333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1850 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       774  (0.0431703); expected 358.6 (0.02)
Passed bias filter:                      468  (0.026103); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 1.02u 0.28s 00:00:01.30 Elapsed: 00:00:00.47
# Mc/sec: 11837.03
//
Query:       EEA19843.1  [L=425]
Description: O-methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.8e-28   98.2   0.0    5.7e-28   97.7   0.0    1.2  1  Methyltransf_2   O-methyltransferase domain
    0.00014   21.7   0.0    0.00027   20.8   0.0    1.4  1  Methyltransf_31  Methyltransferase domain
     0.0039   17.9   0.0      0.011   16.5   0.0    1.8  1  Methyltransf_25  Methyltransferase domain
     0.0079   15.8   0.0      0.016   14.7   0.0    1.4  1  MTS              Methyltransferase small domain
  ------ inclusion threshold ------
       0.02   15.6   0.0      0.048   14.4   0.0    1.7  1  Methyltransf_12  Methyltransferase domain


Domain annotation for each model (and alignments):
>> Methyltransf_2  O-methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.7   0.0   1.6e-31   5.7e-28      25     207 ..     200     398 ..     180     400 .. 0.84

  Alignments for each domain:
  == domain 1  score: 97.7 bits;  conditional E-value: 1.6e-31
                     HHHHHTSSHHHHHHHHHHHHTTHHHHHHHHHHSS-GGG-.....SEEEEET-TTSHHHHHHHHH-TT-EEEEEE-HHHHHHHHHHS.----.... CS
  Methyltransf_2  25 lfeaikrdeeerakfnkglqessslvakkvleafdlegl.....kslvDvGGGtGalakaivsayPtikvivfDlpeVveaAkehl.sage.... 109
                     +f++  + +e  ++f  +++ +s+   + + + f  + l     +++vDvGG  G +  + ++ yP++k iv DlpeV+  A ++l s+++    
      EEA19843.1 200 TFQYLSEHKERATRFAFAMATTSKASLDALSTDFPWSDLsttsgSVVVDVGGSKGHVSLHLARIYPHLKFIVQDLPEVIDGAADQLlSSEAnnda 294
                     68888888888888999999999888888888876555511122469*********************************988887544331122 PP

                     .-TTEEEEES-TTTS.-----SEEEEESSGGGS-HHHHHHHHHHHHHH--TT-EEEEEE----TTS---HHHHHH....HHHHHHCSS-----HH CS
  Methyltransf_2 110 .eervefvgGdffkd.slPeaDaillkrvlhDwsdekcvklLkrvkkalpagGkvivveavlgadpsgeletelv....dlimlvqteGkeRtea 198
                      + r+efv  d+f++ ++ +aD++l+  vlhDw d+ c  +++++  al+ g k+++ + vl++ ++  l +e++    d im+   + +eR++ 
      EEA19843.1 295 lKGRIEFVPHDMFEEqPVKNADIYLFRYVLHDWGDKYCIDVIRNLIPALKRGAKIVIQDHVLPEPGTMGLLQEMQmrsmDAIMMSLFNSREREAD 389
                     2579*********641566*********************************************9999988888888888999999********* PP

                     HHHHHHHHC CS
  Methyltransf_2 199 eyeellsea 207
                     e+++l+s+a
      EEA19843.1 390 EWRDLFSQA 398
                     ******987 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8   0.0   7.5e-08   0.00027       3     119 ..     242     366 ..     240     399 .. 0.72

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 7.5e-08
  Methyltransf_31   3 kglrvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielAre.....naqklgld.nveFeqgdieeleklledekfDlilsnevlnalad. 89 
                      +g +v+D+G  +G+ ++ la +++p+ +++  D  +e+i  A       +a +  l+ ++eF   d++e +     ++ D+ l + vl++  d 
       EEA19843.1 242 SGSVVVDVGGSKGHVSLHLA-RIYPHLKFIVQDL-PEVIDGAADqllssEANNDALKgRIEFVPHDMFEEQPV---KNADIYLFRYVLHDWGDk 330
                      7889****************.*******998776.566666665576667778888889**********5533...68**********888772 PP

  Methyltransf_31  90 .pdkileeiervlkpggilliedpr........llaelp 119
                       + +++++++ +lk g  ++i+d+         l   l 
       EEA19843.1 331 yCIDVIRNLIPALKRGAKIVIQDHVlpepgtmgL---LQ 366
                      25678********************555553331...22 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0     3e-06     0.011       1      96 [.     246     346 ..     246     346 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 3e-06
                      EEEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHHTTT.......TEEEEESBC.CGBSSSTTTEEEEEEESTGGGSSHHHHHHHH CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlgkakvtgvDiseemleaareraeeegl.......nvefvqgda.edlpfedgsfDlvvssgalhhlsdedlekal 86 
                      v+d+G  +G+++l+la+ +++ k++  D+ e    aa + +++ ++       ++efv +d+ e+ p ++   D+ + +++lh + d+   +++
       EEA19843.1 246 VVDVGGSKGHVSLHLARIYPHLKFIVQDLPEVIDGAADQLLSS-EAnndalkgRIEFVPHDMfEEQPVKN--ADIYLFRYVLHDWGDKYCIDVI 336
                      89****************9889999999865554444444443.22234467799999999966677665..9999999999999999999999 PP

                      HHHHHHEEEE CS
  Methyltransf_25  87 keiarvLkpg 96 
                      +++  +Lk g
       EEA19843.1 337 RNLIPALKRG 346
                      9999999976 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   4.5e-06     0.016      20     100 ..     231     317 ..     214     323 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 4.5e-06
                 HHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.E.E.....EEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEE CS
         MTS  20 sklLletlpkelsgkvlDlGcGaGvlgaalakespeae.v.....tlvdvdarAlesakenleanklevevvasdvleeveekkfdl 100
                 +++  + l+++    v+D+G   G ++++la+ +p+++ +     +++d  a  l s+++n  a k ++e+v +d++ee + k+ d+
  EEA19843.1 231 TDFPWSDLSTTSGSVVVDVGGSKGHVSLHLARIYPHLKfIvqdlpEVIDGAADQLLSSEANNDALKGRIEFVPHDMFEEQPVKNADI 317
                 555567788878888*********************99533433446788888999999999999999**********998777775 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   1.3e-05     0.048       1      98 [.     247     348 ..     247     349 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.3e-05
  Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnn..nvelealdlldldggssfDlvvasnvlhhl..kdirevldnir 90 
                      +++G+  G+++ +l++  p++++++ D+ +    +a + l+++ nn++   ++e+   d +++++ +  D+ +   vlh +  k   +v++n+ 
       EEA19843.1 247 VDVGGSKGHVSLHLARIYPHLKFIVQDLPEVIDGAADQLLSSEANNDALkgRIEFVPHDMFEEQPVKNADIYLFRYVLHDWgdKYCIDVIRNLI 340
                      59**************************99999999999998888887622577888888888888***************988888******* PP

  Methyltransf_12  91 klLkpgGr 98 
                       +Lk g++
       EEA19843.1 341 PALKRGAK 348
                      ****9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (425 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       516  (0.0287802); expected 358.6 (0.02)
Passed bias filter:                      502  (0.0279993); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.48
# Mc/sec: 2687.96
//
Query:       EEA19844.1  [L=1099]
Description: H /K ATPase alpha subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.6e-41  140.1   4.0    1.2e-39  135.7   1.6    2.5  2  E1-E2_ATPase     E1-E2 ATPase
    7.8e-38  130.0   1.3    7.8e-38  130.0   1.3    2.9  3  Cation_ATPase_C  Cation transporting ATPase, C-terminus
    1.4e-21   77.8   0.0    6.2e-19   69.1   0.0    3.0  1  Hydrolase        haloacid dehalogenase-like hydrolase
    5.2e-14   52.1   0.0    9.8e-14   51.2   0.0    1.5  1  Cation_ATPase    Cation transport ATPase (P-type)
    1.2e-12   47.3   0.1      5e-12   45.3   0.0    2.1  2  Cation_ATPase_N  Cation transporter/ATPase, N-terminus
     0.0036   17.1   0.0     0.0075   16.0   0.0    1.4  1  Hydrolase_3      haloacid dehalogenase-like hydrolase
     0.0065   16.9   1.0      0.032   14.7   1.0    2.2  1  DUF2231          Predicted membrane protein (DUF2231)
     0.0091   15.8   6.8      0.016   15.0   0.2    2.9  3  DUF2157          Predicted membrane protein (DUF2157)
  ------ inclusion threshold ------
       0.59    9.5   4.5       0.42   10.0   0.2    2.4  2  TMEM43           Transmembrane protein 43


Domain annotation for each model (and alignments):
>> E1-E2_ATPase  E1-E2 ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.0     0.014        28     117     156 ..     154     194 ..     105     202 .. 0.63
   2 !  135.7   1.6   6.1e-43   1.2e-39       2     180 ..     220     418 ..     219     419 .. 0.95

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.014
                   HHHHHHHHHHHHHHHHHHHS-STTTSSTT.HHHHHHHHHHH CS
  E1-E2_ATPase 117 klgkvlvpvvlliallvflialllgksla.eallralallv 156
                    ++k + ++ l+ ++lvf+ +  lg+++a   l  a++ll 
    EEA19844.1 154 YFFKGFGVILLAGCILVFVSWKPLGDPPAvANLALAIVLLA 194
                   3567799999999********99999998533333444443 PP

  == domain 2  score: 135.7 bits;  conditional E-value: 6.1e-43
                   SS--EEEEE.-TTS-EEEEGGG--TTSEEEEETT-B--SEEEEEEE-S..EEE-TTTS---S-EE-..........G-TTEE-TT-EEEE-EEEEEE CS
  E1-E2_ATPase   2 llpptakvi.rdgteeeidakelvpGDivllkagdrvpaDgrivegsa..evdesaLTGEslpvek..........ekgdmvfsGtvvvsgeakavV 85 
                   +lp+++ vi ++g++++i+a+e+vpGD++++kag++ paD+r v+ s+   +d s+LTGEs+pv            e+++   +Gt  vsg+a a+V
    EEA19844.1 220 MLPESCIVIrNAGNQVNIPAAEIVPGDVIQIKAGNKLPADVRFVHVSNdaYFDRSILTGESVPVNGtidateenylETQNIGLQGTHCVSGNALAIV 316
                   67999999967789*******************************99889***********************9999******************** PP

                   EE-TTTSTTTTTSTTS--------HHHHHHHHHHHHHHHHHHHHHHHHHHS-STTTSSTT.......HHHHHHHHHHHHHS-TTHHHHHHHHHHHHH CS
  E1-E2_ATPase  86 tatgedtelgkiarlveeakskktplqkkldklgkvlvpvvlliallvflialllgksla.......eallralallvaaiPcaLplavplalalga 175
                   + tg +t +g+ia+l++e+k+  t l+k++  +++ +v+++l+++++v++++ ++ ++         + ++  +++++a+iP++Lp+ ++ +l++ a
    EEA19844.1 317 VSTGDNTVFGRIAKLASEPKPGLTLLEKEVLHFVALIVAIMLTMIIVVIIVWATWLRKDHpgwinvpTLIVDCVSVAIAFIPEGLPISITASLTITA 413
                   ************************************************9999998777777889**888888***********************99 PP

                   HHHHH CS
  E1-E2_ATPase 176 rrlak 180
                   + + k
    EEA19844.1 414 NIMRK 418
                   99987 PP

>> Cation_ATPase_C  Cation transporting ATPase, C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.4      0.81   1.6e+03      59      78 ..     186     205 ..     150     227 .. 0.62
   2 ?    2.1   0.8      0.07   1.4e+02     128     162 ..     348     382 ..     331     402 .. 0.62
   3 !  130.0   1.3   3.9e-41   7.8e-38       1     181 [.     882    1084 ..     882    1085 .. 0.91

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.81
  Cation_ATPase_C  59 llqalvtllvffltlllfgi 78 
                      l +a+v l+vff+ + ++++
       EEA19844.1 186 LALAIVLLAVFFIQAGFNAW 205
                      44455555555555544433 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.07
  Cation_ATPase_C 128 lllaillslllqvlivyvpglnavfgtaplsleew 162
                       ++a++++++l+++iv + + +++++   +++ ++
       EEA19844.1 348 HFVALIVAIMLTMIIVVIIVWATWLRKDHPGWINV 382
                      45566666666666666666666666666666655 PP

  == domain 3  score: 130.0 bits;  conditional E-value: 3.9e-41
  Cation_ATPase_C    1 plplsaiqiLwinLvtDllpalaLaleppekdimkrpPr.kkkepliskkmlrri.liqgllqalvtllvffltll...........lf... 76  
                       p++ls+ +++ i  +tD  +a++La+e+pe+d++ rpPr ++k++l+++k+++++ +++g++q+++++ + +++l+           +f   
       EEA19844.1  882 PQVLSSFLMIVICCFTDCAAATVLAYEKPEADVLLRPPRnPRKDKLVDWKLMLHAyGVIGIIQTICSFSMSYWYLQrngipfsslwfGFgav 973 
                       789********************************************************************999996666666655511545 PP

  Cation_ATPase_C   77 ..gisekenklssnyaqtmaFitlvlsqifnalnlrsrreslfkfsglf....snkllllaillslllqvlivyvpglnavfgtaplsleew 162 
                         gi+e++ + + n a++++Fi lv++q+fn++++r+rr s+f+    f    +n ll+ ai+++l+++++ +y+p l++v++t+ +++e++
       EEA19844.1  974 paGIDEEYYSNKLNEASSIYFINLVVMQWFNLMAIRTRRLSIFSHPPAFnketQNILLFPAIIFALGIAAFWLYIPRLQSVLDTTGVPAEHY 1065
                       556666665555899*****************************88888999999************************************* PP

  Cation_ATPase_C  163 lialllalvvllvdelvKl 181 
                       ++ ++++l +l++de +K 
       EEA19844.1 1066 FLPAAFGLGLLIMDEGRKA 1084
                       ****************996 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.1   0.0   3.1e-22   6.2e-19       2     210 .]     436     813 ..     435     813 .. 0.82

  Alignments for each domain:
  == domain 1  score: 69.1 bits;  conditional E-value: 3.1e-22
                 SEEEEESBTTTBCHHHHHHHHHHHH.................................CHHHHHHHHHH..HHCHHHHHHHHHHHHH....HHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxx.................................xxxxxxxxxxx..xxxxxxxxxxxxxxxx....xxxxxxxx RF
   Hydrolase   2 ktvvfDkdGTLttgepsvedvivsa.................................alalaaaletg..sehpigkalvaaakar....sgaltgfa 61 
                  +++ Dk+GTLt+ ++ v+d+  s                                  a +  aa e    +e+pi+   + +a  r     g++++++
  EEA19844.1 436 SVICSDKTGTLTRNKMFVTDCAISTsvfnspmtardetvlkgkstgvhqlralsglcnAAEFDAAAENMplNERPIFGDATDQAILRfselLGPVSEIR 534
                 5899****************9999988878787777777777777777766666555544444444444777777777776666666666655556666 PP

                 H.........ETTTE.....................................................HHHHTHHHHHHHHHCHHHHHHHHHHHHHHCH CS
                 x.........xxxxx.....................................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase  62 t.........figrg.....................................................ayaigkpewltaldippdlgaaigsaqsqgr 98 
                 +         f   +                                                     + a g+++ l+a+    + +   +++  +g+
  EEA19844.1 535 RlwkktwelaF---NsrnklmirtftvaeskgfglalspvesmqfkpedtlltikgapdiliercgylVTADGSVQTLDAE-TLRQIKGIKDEWSNKGK 629
                 65445555552...0444666666666666677799999999999999999999999999999999998888888888888.77888999999999999 PP

                 HHHHH.............................TTHHHHHHHHHHTHHBHTTHHHHHHHHHHTTEEEEEEESSEHHHHHHHHHHTT....GGGE.SEE CS
                 xxxxx.............................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxx.xxx RF
   Hydrolase  99 tvall.............................qaralavftiadplkvkpeaaeavasLkaagievvlltgdnpetaeraanqlG....ddyf.dav 163
                  v+ll                             +  +++++ i dp  +++e+  +v++L++agi+++++tgd+  ta ++a+q+G     +   +  
  EEA19844.1 630 RVILLarkvivaqdimttpgsheyeseimrqaksDLILVGLVGIVDP--PREEIPAVVKTLRRAGIRIFMVTGDFGLTALAIARQCGivsaSRVEdATA 726
                 99999*************************999999***********..**************************************998744443344 PP

                 EEHHCES....STTT....................................SHHHHHHHHHHHTSTGGGEEEEESSHHHHHHHHHTT CS
                 xxxxxxx....xxxx....................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase 164 iasdiet....vakp....................................spegkvaaireLqgkpeevamVGDgvnDaaalaaAg 210
                 +++++++    v kp                                     pe+k++++re+q + e v m GDgvnDa+ l+aA+
  EEA19844.1 727 LQRYNSGremiVDKPehtpsaivisgsellslndtqwdqlcgyqeivfartTPEQKLRIVREFQSREEIVGMTGDGVNDAPSLKAAD 813
                 4444444788899999999*********************************************88888*****************8 PP

>> Cation_ATPase  Cation transport ATPase (P-type)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.2   0.0   4.9e-17   9.8e-14       2      90 ..     491     598 ..     490     599 .. 0.95

  Alignments for each domain:
  == domain 1  score: 51.2 bits;  conditional E-value: 4.9e-17
  Cation_ATPase   2 lcNsaaf...sensekdevkllGnktEsALlvlaeklgldteelreetkkvqeipFnssrKrmsvvlkle.................pekkvrlyv 77 
                    lcN a+f    en++ +e+ ++G++t++A+l++ e l   ++e+r+ +kk  e+ Fns +K m+  ++                   + +  +l++
     EEA19844.1 491 LCNAAEFdaaAENMPLNERPIFGDATDQAILRFSELL-GPVSEIRRLWKKTWELAFNSRNKLMIRTFTVAeskgfglalspvesmqfKPEDTLLTI 585
                    8********99**************************.9************************9777766788**************9999***** PP

  Cation_ATPase  78 KGApeiilkrCth 90 
                    KGAp+i+++rC++
     EEA19844.1 586 KGAPDILIERCGY 598
                    ***********97 PP

>> Cation_ATPase_N  Cation transporter/ATPase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.3   0.0   2.5e-15     5e-12       1      67 [.     103     169 ..     103     171 .. 0.80
   2 ?   -2.3   0.1       1.8   3.7e+03      33      60 ..     981    1008 ..     979    1008 .. 0.87

  Alignments for each domain:
  == domain 1  score: 45.3 bits;  conditional E-value: 2.5e-15
  Cation_ATPase_N   1 ehalsleevlekLetdlenGLtqaeaaerlkkyGpNelkekkkkslwvkllkqftnplvilLlvaal 67 
                      +h+ls   + ++L++d  +GL+++++++rl++yG+N+l++ +++ +++ +   f+ + vilL  + l
       EEA19844.1 103 WHTLSTTSLEKRLQVDVAHGLSSDQIQQRLREYGKNVLSPTPHRWFMQVFGYFFKGFGVILLAGCIL 169
                      99************************************55555555555555556666666666655 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1.8
  Cation_ATPase_N   33 yGpNelkekkkkslwvkllkqftnplvi 60  
                       y +N+l+e     ++ +++ q+ n++ i
       EEA19844.1  981 YYSNKLNEASSIYFINLVVMQWFNLMAI 1008
                       557999999999999*********9976 PP

>> Hydrolase_3  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   3.8e-06    0.0075     204     243 ..     794     833 ..     783     839 .. 0.86

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 3.8e-06
                  GGEEEEESSGGGHHHHHHSSEEEEETTS-HHHHHHSSEEE CS
  Hydrolase_3 204 eeviafGDgeNDieMLeaaglgvAmgnaseevkkaAdyvt 243
                  e v   GDg ND + L+aa++g+A+g++s+ +++a+d+v 
   EEA19844.1 794 EIVGMTGDGVNDAPSLKAADIGIALGSGSDIAIEASDMVL 833
                  555567*******************************996 PP

>> DUF2231  Predicted membrane protein (DUF2231)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   1.0   1.6e-05     0.032      21      89 ..     324     397 ..     309     401 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.6e-05
     DUF2231  21 laGlvelllaepsi..rakktallHa...vggvlllalivaltvWrfvlrlreeeqvsplylalslvvvvlllv 89 
                 ++G +  l+ ep++  +  +   lH+   +++++l+++iv++ vW  +lr++++  +++  l+++ v v++ ++
  EEA19844.1 324 VFGRIAKLASEPKPglTLLEKEVLHFvalIVAIMLTMIIVVIIVWATWLRKDHPGWINVPTLIVDCVSVAIAFI 397
                 66666666666666664455555665112689999********************************9999876 PP

>> DUF2157  Predicted membrane protein (DUF2157)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.2   8.1e-06     0.016       9     101 ..     123     221 ..     119     230 .. 0.86
   2 ?    3.3   0.5     0.032        63      66     110 ..     352     396 ..     345     400 .. 0.69
   3 ?   -3.2   0.0       3.3   6.5e+03      53      63 ..    1040    1050 ..    1023    1057 .. 0.55

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 8.1e-06
     DUF2157   9 Iteeqaqallaryeaeeresarrrsf....leallvlGalllglGlilfvAan.Wqglsrlvkfllllvllllslllg.avlwrdrrvpprlgeallll 101
                 ++++q q+ l++y+++   +++ r f    + ++ + G++ll+  +++fv++    + + ++ ++l++vll+++++ + + +w+d  ++++++ + ++l
  EEA19844.1 123 LSSDQIQQRLREYGKNVLSPTPHRWFmqvfGYFFKGFGVILLAGCILVFVSWKpLGDPPAVANLALAIVLLAVFFIQAgFNAWQDWSSSRVMASITAML 221
                 5677888888889988888887777788889999999*************998889999*************************998888888777766 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.032
     DUF2157  66 kfllllvllllslllgavlwrdrrvpprlgeallllaalllgaai 110
                  ++ +++ +++++++++ +w ++++p ++    l++ ++ + +a+
  EEA19844.1 352 LIVAIMLTMIIVVIIVWATWLRKDHPGWINVPTLIVDCVSVAIAF 396
                 345555555666666688888888888988888888888777665 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 3.3
     DUF2157   53 fvAanWqglsr 63  
                   +Aa+W  ++r
  EEA19844.1 1040 GIAAFWLYIPR 1050
                  24556666655 PP

>> TMEM43  Transmembrane protein 43
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.2   0.00021      0.42     184     239 ..     144     194 ..     129     203 .. 0.78
   2 ?   -0.0   0.7      0.24   4.8e+02     221     246 ..     346     371 ..     323     374 .. 0.61

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00021
      TMEM43 184 lltwllRllGfllmflglllllsplsvlvslipllgelvglglalvalllslslsl 239
                  + w++ ++G++   +g++ll+ ++ v+vs+ pl     g   a+++l+l+++l  
  EEA19844.1 144 PHRWFMQVFGYFFKGFGVILLAGCILVFVSWKPL-----GDPPAVANLALAIVLLA 194
                 579******************************9.....44444555555544433 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 0.24
      TMEM43 221 lvglglalvalllslslsllvialaw 246
                 ++ ++  +va++l++++ ++++   w
  EEA19844.1 346 VLHFVALIVAIMLTMIIVVIIVWATW 371
                 33444445555555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1099 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       779  (0.0434492); expected 358.6 (0.02)
Passed bias filter:                      470  (0.0262145); expected 358.6 (0.02)
Passed Vit filter:                        64  (0.00356964); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.80u 0.28s 00:00:01.08 Elapsed: 00:00:00.45
# Mc/sec: 7375.71
//
Query:       EEA19845.1  [L=329]
Description: bZIP transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.3e-09   35.8   7.6    1.7e-08   34.4   7.6    1.7  1  bZIP_1    bZIP transcription factor
  ------ inclusion threshold ------
      0.086   13.3   0.3       0.23   11.9   0.3    1.7  1  ParB      ParB family
       0.15   12.2  10.9          9    6.5   9.7    2.8  2  bZIP_2    Basic region leucine zipper
          4    7.7   7.6       0.29   11.4   1.4    2.0  2  HALZ      Homeobox associated leucine zipper


Domain annotation for each model (and alignments):
>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.4   7.6   3.7e-12   1.7e-08       2      61 ..      99     161 ..      98     164 .. 0.88

  Alignments for each domain:
  == domain 1  score: 34.4 bits;  conditional E-value: 3.7e-12
                 XXXXXXXXX--HHHHHHHHHHHHHHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1   2 kelKrekrkqkNReaArrsRqRKqaeieeLerrvk...aLekeNksLkseleelkkevekLks 61 
                 +el   kr+++NR a+r++RqRK+ +i +Le +vk   +L++  k+L+ e+ +l++ + +L+s
  EEA19845.1  99 RELSTSKRAEQNRAAQRAFRQRKEGYIRQLEAQVKdykVLSESYKALQAENYQLREYIISLQS 161
                 677789**************************995443899999999******9999988876 PP

>> ParB  ParB family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.3   5.1e-05      0.23       8      44 ..     131     167 ..     126     177 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 5.1e-05
        ParB   8 tlaDYklLlkvaeklekkdvelseliekvkeeiekvq 44 
                  ++DYk+L++ ++ l++++ +l e i ++++++ + q
  EEA19845.1 131 QVKDYKVLSESYKALQAENYQLREYIISLQSRLIDSQ 167
                 689**************************99976634 PP

>> bZIP_2  Basic region leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   9.7     0.002         9       4      46 ..     101     154 ..      98     162 .. 0.70
   2 ?   -3.0   0.0       1.8   8.1e+03      12      17 ..     258     263 ..     257     273 .. 0.79

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.002
                 XXXXXXX.XXXXXXXX-HHHHHHHHHHHHHHHHH..........HHHHHHHHHH CS
      bZIP_2   4 eyrerRr.kNreAarrsRekkkakeeeleervke..........LeeeNaqLrq 46 
                  ++ +R  +Nr+A r +R++k  + ++le +vk+          L++eN qLr+
  EEA19845.1 101 LSTSKRAeQNRAAQRAFRQRKEGYIRQLEAQVKDykvlsesykaLQAENYQLRE 154
                 57889999*********************9998733322222224555555555 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.8
                 XXXXXX CS
      bZIP_2  12 NreAar 17 
                 Nr+A++
  EEA19845.1 258 NRIAVA 263
                 9***97 PP

>> HALZ  Homeobox associated leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.5      0.38   1.7e+03      21      36 ..      26      41 ..      22      42 .. 0.82
   2 ?   11.4   1.4   6.4e-05      0.29       5      41 ..     133     162 ..     126     164 .. 0.73

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.38
        HALZ 21 ydsLkkenekLkaelq 36
                +d+L++  + L+++ q
  EEA19845.1 26 HDQLLAAQQHLQSQGQ 41
                7999999999999965 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 6.4e-05
        HALZ   5 rDYdvLKasYdaLksdydsLkkenekLkaelqeLkek 41 
                 +DY+vL  sY aL+       +en +L+  + +L ++
  EEA19845.1 133 KDYKVLSESYKALQ-------AENYQLREYIISLQSR 162
                 79999999999999.......8888887777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (329 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1352  (0.0754086); expected 358.6 (0.02)
Passed bias filter:                      603  (0.0336327); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.59u 0.30s 00:00:00.88 Elapsed: 00:00:00.44
# Mc/sec: 2224.75
//
Query:       EEA19846.1  [L=755]
Description: chromatin remodeling complex subunit (Arp5), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      5e-57  193.4   0.0    3.6e-54  183.9   0.0    2.3  1  Actin       Actin
  ------ inclusion threshold ------
          9    5.5   8.5         21    4.3   8.5    1.5  1  CorA        CorA-like Mg2+ transporter protein


Domain annotation for each model (and alignments):
>> Actin  Actin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  183.9   0.0     4e-58   3.6e-54       3     402 ..      56     744 ..      54     747 .. 0.85

  Alignments for each domain:
  == domain 1  score: 183.9 bits;  conditional E-value: 4e-58
       Actin   3 evsavVlDnGssttraGyagedaPkavipslvgkprgrkvea.klyvgdealt.krpelevrspv..edGvvedwdaveelwehvlkeelkvd....pe 93 
                 ++sa+V+DnGs+t++aG++ +++P+ ++p ++ ++r+rk ++   ++g +a+    +  ++r+      +vv +wd++e ++++v+ + l vd    + 
  EEA19846.1  56 SSSAIVIDNGSHTVKAGWSFDKFPRFMLPPVMSRYRDRKLNKaCQFIGYDAYVdATTRGQLRYAFdpGTSVVGNWDVMEGVLDYVFLK-LGVDgsqgSV 153
                 579***********************************988755678888555356666666666226779***************98.6666556679 PP

       Actin  94 ehpllltepplnppkqrekalEivfEkfkvpalylaksavlsafasgkstglvvDsGasvtsvvpVldGyvLkkairrsdlgGkaLteqlkellssknv 192
                 + p+++tep  n +  r  + Ei+fE ++vp++  + +  +s  ++  +tglvv s +++t+v+pVl+  +L    +r++ gG + +e+l +l++ k  
  EEA19846.1 154 DRPIVMTEPIANLTYPRRMMNEILFECYGVPSVAYGIDSLFSYRYNHGKTGLVVSSSHTSTHVIPVLNSKALLSNATRLNWGGMQASEYLLKLMRLK-Y 251
                 9**************************************99987777779**********************************************5.5 PP

       Actin 193 evtprylikkkkvveaessae................keelekltesyk.tleeeevleeiKesvcevsedpeg.....deekss........sspeks 261
                    p  +i+++     ++                      le+ ++  +  + e+ v+e+ +e++ +++e +++     +e++++        +     
  EEA19846.1 252 PTFPARMIEHQMEDLVHKLCYvstdyneelshfldwtG--LEDRDYVVQyPFTEHVVVEKTQEELDKIAERKKEsgrrlQEQAAKmrleklmkK----- 343
                 55566666655432222221134555444666655331..333333322134566667777777777777666666555222222555545442..... PP

       Actin 262 YeLPDg............................................................................................. 267
                                                                                                                    
  EEA19846.1 344 -----Eqeleyykdlqqklasqtkkevrrileaedmkdethlertirdlersikrsrnkdlgvdeteenpeeatfpmldipdeeldeaglkekrhqrlm 437
                 .....033333333445566667777777777777788888888888888888888888888888888888888888888888**************** PP

       Actin 268 ................................................................................................... 267
                                                                                                                    
  EEA19846.1 438 ksnmearqrakaekeaekarieeeqrldderrendfeawigerraardallqkikererlkadlgnrkslasqmrmktlanlaadgpkkrrrggddddf 536
                 *************************************************************************************************** PP

       Actin 268 ................................................................................seiklgeeRfkvpEiLFdp 286
                                                                                                 ++i l+ eR +vpE+ F+p
  EEA19846.1 537 gaddadwgvyrqvatgeqsddeeeedlgvtlktledqllqydpdfthehtldaqsdwtkslvhvflrgpwpfdlesqreaHQIHLNVERIRVPEVVFQP 635
                 ******************************************************************************999****************** PP

       Actin 287 sligsesaleeekskllgiselivaaina..cdvdlrpeLlanivvtGGnsllpglteRlekelaqlaskgvkvkiiapeeerkysaWiGGSiLAslg. 382
                 s++g ++a         g+ e++ + +n+  +  + r  Ll+ + +tGGn+l++g++eRl +el  +++++  + ++++  ++   aW G++ +As+g 
  EEA19846.1 636 SIAGVDQA---------GLVEIAADILNQrfTAEEDRTRLLKDVFLTGGNTLFKGFEERLRTELVGVLPTNAPLHVRRAV-DPVLDAWKGAAQWASTGs 724
                 ********.........**********9833345669*******************************************.****************95 PP

       Actin 383 tfqqlwvskqEYeEqGssvv 402
                 ++    +s++EY+E+Gs++ 
  EEA19846.1 725 ELATWSISRAEYQEKGSEYL 744
                 666677**********9976 PP

>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   8.5    0.0023        21     119     204 ..     306     394 ..     304     408 .. 0.77

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.0023
        CorA 119 ivdrlfellekleeeldeledeledstkkeilrelaqlrrrlvkl....rralapnrevlkrllakaddklldded.keylrdlldelerl 204
                 +v++  e+l+k+ e+ +e  ++l+++  k  l++l++ +++l ++    ++ ++++++ + r+l+   +++ d+++ ++ +rdl+  ++r+
  EEA19846.1 306 VVEKTQEELDKIAERKKESGRRLQEQAAKMRLEKLMKKEQELEYYkdlqQKLASQTKKEVRRILE--AEDMKDETHlERTIRDLERSIKRS 394
                 79999****************************************88886666666666758888..333333333024466666666664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (755 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1828  (0.101958); expected 358.6 (0.02)
Passed bias filter:                      541  (0.0301746); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.84u 0.37s 00:00:01.21 Elapsed: 00:00:00.52
# Mc/sec: 4348.94
//
Query:       EEA19847.1  [L=72]
Description: DASH complex subunit Dad4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.1e-32  111.8   6.8    1.2e-32  111.7   6.8    1.0  1  DASH_Dad4  DASH complex subunit Dad4
     0.0083   16.3   0.5     0.0094   16.1   0.5    1.1  1  GM_CSF     Granulocyte-macrophage colony-stimulating factor
  ------ inclusion threshold ------
      0.051   13.8   3.8      0.077   13.2   3.8    1.3  1  DASH_Dad1  DASH complex subunit Dad1


Domain annotation for each model (and alignments):
>> DASH_Dad4  DASH complex subunit Dad4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.7   6.8     2e-36   1.2e-32       1      71 []       1      71 [.       1      71 [. 0.99

  Alignments for each domain:
  == domain 1  score: 111.7 bits;  conditional E-value: 2e-36
   DASH_Dad4  1 MeNPheeqqsalLsRIiknvekLnesvvelnkeleeinkkNknvelvsqlwenYqrnvqfnLeatgelkeP 71
                Me+Phe+qqs lLsRIi+n+ekLne+v+ lnk+l+e+n +N+nvelv+q+++nYq+nv f+Leat++ k+P
  EEA19847.1  1 MESPHEHQQSLLLSRIITNIEKLNEAVMVLNKSLQEVNVQNMNVELVAQMFKNYQSNVLFHLEATDNIKDP 71
                *********************************************************************98 PP

>> GM_CSF  Granulocyte-macrophage colony-stimulating factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.5   1.6e-06    0.0094      11      51 ..      15      55 ..       6      63 .. 0.87

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 1.6e-06
                -TTHHHHHHHHHHHHHHH----HHHHTSEEEEESS--BSSS CS
      GM_CSF 11 rpwkhvdaikealsllnessdlaavlneevevvseefdlqe 51
                r    ++ ++ea+ +ln+s +  +v n +ve+v+++f+  +
  EEA19847.1 15 RIITNIEKLNEAVMVLNKSLQEVNVQNMNVELVAQMFKNYQ 55
                66678999*****************************8755 PP

>> DASH_Dad1  DASH complex subunit Dad1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   3.8   1.3e-05     0.077       3      50 ..       6      53 ..       5      58 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.3e-05
   DASH_Dad1  3 erqRdrliqeIaesmeevlnnlnaLNRsLEeviavgkeFesVaaLWss 50
                e q ++l++ I +++e++ + +  LN+sL ev+      e Va++ ++
  EEA19847.1  6 EHQQSLLLSRIITNIEKLNEAVMVLNKSLQEVNVQNMNVELVAQMFKN 53
                7899***************************99766666666666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (72 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1469  (0.0819343); expected 358.6 (0.02)
Passed bias filter:                      601  (0.0335211); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.45
# Mc/sec: 478.27
//
Query:       EEA19848.1  [L=193]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-14   53.5   0.2    2.4e-14   52.8   0.2    1.4  1  YL1_C     YL1 nuclear protein C-terminal domain


Domain annotation for each model (and alignments):
>> YL1_C  YL1 nuclear protein C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.8   0.2   1.4e-18   2.4e-14       1      28 [.     143     170 ..     143     171 .. 0.96

  Alignments for each domain:
  == domain 1  score: 52.8 bits;  conditional E-value: 1.4e-18
       YL1_C   1 yCdITGlpAkYrDPkTgLpYanveaykv 28 
                 yCd TGlpA+Y+DPkT+L+Y+n e++ v
  EEA19848.1 143 YCDLTGLPAPYTDPKTRLRYHNREIFGV 170
                 9*************************77 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (193 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       697  (0.0388756); expected 358.6 (0.02)
Passed bias filter:                      430  (0.0239835); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 1381.54
//
Query:       EEA19849.1  [L=336]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
      0.016   15.9   0.1      0.034   14.9   0.1    1.5  1  Complex1_LYR_2  Complex1_LYR-like
      0.029   15.3   0.0      0.054   14.4   0.0    1.4  1  2OG-FeII_Oxy_3  2OG-Fe(II) oxygenase superfamily


Domain annotation for each model (and alignments):
>> Complex1_LYR_2  Complex1_LYR-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   0.1   3.8e-06     0.034      23      56 ..     288     327 ..     255     334 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 3.8e-06
  Complex1_LYR_2  23 gdayvraefrrhk.....hlk.npeeialflknqreYael 56 
                     + +++r+++r+ +      l+ + + +++fl++qreY ++
      EEA19849.1 288 LEERIRDQLRKVRerkraSLEfDTKGVKEFLREQREYIDT 327
                     4444444444432344559******************996 PP

>> 2OG-FeII_Oxy_3  2OG-Fe(II) oxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   6.1e-06     0.054      10      93 ..     175     249 ..     167     252 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 6.1e-06
                     -EEEEE-SS----TT.-.EEEEEEEEE....ET-B--EEE..........-.--TT-EEEEE-..B-TEEE--B.-SS-EEEEEE CS
  2OG-FeII_Oxy_3  10 qeykpHvDnfekeegsgqrrltvllyLnekeseeGGelelyekdkeavkik.pkkgrlvlFesdellpHevlpvtkggeRlsltg 93 
                       + +H+D+           + ++ +L++ +   GGe +++  +++ +k++ p +g +v+ + + + +H++l+ + g eR+++ +
      EEA19849.1 175 TAFAWHYDSV---------PFVCVTMLSDCTGMVGGETAVRLGEDKVMKVRgPTQGCAVIMQGRYI-EHQALKARGGAERITMIT 249
                     5689999964.........356666665535689***999888888888889***********877.7*****97766***9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (336 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       676  (0.0377043); expected 358.6 (0.02)
Passed bias filter:                      569  (0.0317363); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.47
# Mc/sec: 2155.54
//
Query:       EEA19850.1  [L=648]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      5e-47  160.5   8.1    1.2e-46  159.3   6.4    1.9  2  Fungal_trans_2   Fungal specific transcription factor domain
  ------ inclusion threshold ------
      0.057   12.7   0.0        0.1   11.9   0.0    1.3  1  MIS13            Mis12-Mtw1 protein family
       0.11   12.8   2.5       0.39   11.1   0.1    2.7  3  Siah-Interact_N  Siah interacting protein, N terminal


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0     0.031   1.9e+02     189     229 ..       5      50 ..       3      85 .. 0.78
   2 !  159.3   6.4     2e-50   1.2e-46       1     376 [.     185     638 ..     185     642 .. 0.90

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.031
  Fungal_trans_2 189 lmGcsnslilliseisrLarekrsarkd.....seleplsileeas 229
                     ++G+s+ l ++i+ +   + e+ +++ +     s+++ ++ile+++
      EEA19850.1   5 IVGLSSALAYIIANVLLKDDERARHTAQiisstSNTSLNAILEQID 50 
                     68***********************999665554444444444443 PP

  == domain 2  score: 159.3 bits;  conditional E-value: 2e-50
  Fungal_trans_2   1 elldyyldnvapllspvpes.snpfrkvllplalsnk..............allhallalsafhl....qskgpkds.....lereakrykslal 71 
                     +lld y +++ +++ pv     +p+ ++++p  +++               +l+ a+l +safhl     ++    +     ++   ++++ +a 
      EEA19850.1 185 HLLDRYRNSLITSFLPVRKYhTSPWESIHVPKVHEALgeamvsgevthakmGLFFAVLGASAFHLhmqtYNM----GmydqrWKVLGENFRLRAR 275
                     589****************99********************************************6644334....334559************* PP

  Fungal_trans_2  72 kelqealaelsstlsrnekykdiLaaiLllcsieissgdvsdwrvhLeaatsliksrggskasssslsskarfllrifayldilssttlg..... 161
                     k+l+ +la+ls+t++  e+  d++ a  ++  i ++s + +d  ++L+   +li+ +g      s++s ++r l++if y+ ++++t        
      EEA19850.1 276 KRLRLSLANLSTTMP-AEQVADTILAFTSMYTISVVSAQLEDTYIYLREINRLIAIYGME---LSRISTTLRILHNIFYYIQTMQDTVGVfsggn 366
                     ***************.********************************************...***********************9999***** PP

  Fungal_trans_2 162 ..........................rgpsfpseeyekllen....kkeesdsgldplmGcsnslilliseisrLarekrsarkd..seleplsi 224
                                                ++ ++s+  +++l+     ++++s+s ++ ++ ++ sl++lis++++L+ e ++  +   + ++ +s+
      EEA19850.1 367 lirspslrakrsilvdsvnsdsghwsLKGFPSSDTASSILDAcvceDDSSSQSLFERVFSVPISLFQLISRVTALVHETEEVANNgtTHTNLSSL 461
                     **9999999999999999999999964444444444444444554334444555888**************************998888899999 PP

  Fungal_trans_2 225 leeaseleqrllswkprssdlepdldeterassls....................kdl.telfrlaaliylyrlvlglpps..spevqelvkkll 296
                     +  +++le+++ +w  + s++++d  + +++++l+                    +++  e+++ a l+y+yr+v++++p   +++v ++v +l+
      EEA19850.1 462 SYTVNQLETEIWDWNANVSSTSKDALSPSPTTCLHeipfsspapldtrnqpiespLHHyIEAMHSAVLVYFYRCVRKVDPLmiQHLVDKVVESLT 556
                     9999**************************************************96667**********************88888888888888 PP

  Fungal_trans_2 297 ellellpsspvaiasLlWplFiaGceavdeddRdfvrrrleele.qsrlgnvrrarqvleevWrrrd.dgeekidWrdvmek 376
                      ++el ++s+  ++  +W+lF+aGce  +++ R+ v+++++    +++++ +++a q   evW+ rd  ++ + +W +v+++
      EEA19850.1 557 LCTELRQQSNDPSSDTCWALFVAGCEVLNPATRKRVKDLFAIERsRTGIRMFEKASQAAMEVWSVRDrRKNRHLSWSTVLKE 638
                     888888888889***************************9887778999******************66666999***9944 PP

>> MIS13  Mis12-Mtw1 protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   1.7e-05       0.1     125     207 ..     390     499 ..     378     542 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 1.7e-05
                 CCHHHHHHCHHHTHCSTTGCCC.SXXX...............................XXSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH... CS
       MIS13 125 dWeareeeeeedendteltklF.ednd...........................kkklpnaknieneenlailkekikalknEikeWaklladskdpdk 195
                  W  + ++  ++   + l ++  ed+                            + + + a+n +   nl+ l+  +++l+ Ei  W++ ++ +++ ++
  EEA19850.1 390 HWSLKGFPSSDT-ASSILDACVcEDDSssqslfervfsvpislfqlisrvtalvHETEEVANNGTTHTNLSSLSYTVNQLETEIWDWNANVSSTSKDAL 487
                 599999999999.889999999888888999999999*************99999999999999**************************988777666 PP

                 HH.HHHHHHTT- CS
       MIS13 196 eiqkekklvdse 207
                 ++ + + l + +
  EEA19850.1 488 SPSPTTCLHEIP 499
                 665555544433 PP

>> Siah-Interact_N  Siah interacting protein, N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.2       0.9   5.4e+03       5      24 ..      74      93 ..      72     106 .. 0.75
   2 ?    0.0   0.0      0.18   1.1e+03      31      70 ..     463     506 ..     460     511 .. 0.57
   3 ?   11.1   0.1   6.5e-05      0.39      17      35 ..     584     602 ..     582     626 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 0.9
  Siah-Interact_N  5 elqkDlEElkkLlekAtRkr 24
                     +++k +EEl + ++  +++r
       EEA19850.1 74 NTKKEVEELESVISGNRKAR 93
                     77888888888777666665 PP

  == domain 2  score: 0.0 bits;  conditional E-value: 0.18
  Siah-Interact_N  31 aeirKleteilklkekqkakaqqksq....lleeekpaasvapi 70 
                        +  letei   + + +++++   +    +  +e p +s ap 
       EEA19850.1 463 YTVNQLETEIWDWNANVSSTSKDALSpsptTCLHEIPFSSPAPL 506
                      567789****7666665555544333444444555566555555 PP

  == domain 3  score: 11.1 bits;  conditional E-value: 6.5e-05
  Siah-Interact_N  17 lekAtRkrVkdlLsaeirK 35 
                      l+ AtRkrVkdl+++e+++
       EEA19850.1 584 LNPATRKRVKDLFAIERSR 602
                      678*************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (648 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       736  (0.0410508); expected 358.6 (0.02)
Passed bias filter:                      548  (0.030565); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.45
# Mc/sec: 4282.97
//
Query:       EEA19851.1  [L=139]
Description: Got1 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.5e-14   52.3  13.1    8.3e-14   52.0  13.1    1.1  1  Got1      Got1/Sft2-like family


Domain annotation for each model (and alignments):
>> Got1  Got1/Sft2-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.0  13.1   4.6e-18   8.3e-14       6     111 ..      19     114 ..      13     116 .. 0.90

  Alignments for each domain:
  == domain 1  score: 52.0 bits;  conditional E-value: 4.6e-18
        Got1   6 lls...llglpllflkprkFallytlGnilflastafLiGpkkqlkkmfskerliativyllsllltLyaalvlkstlltllfvivqllallwyllsyi 101
                 + +   + g++++f+     + ++++Gnilfl++++++iG++k++ ++ ++ +l +t+++ +++ll+L+ +++       l++++v+l+++l+++ +++
  EEA19851.1  19 GGGlflFGGVLMFFD-----RSMLAMGNILFLIGLTLIIGIQKTIAFFSRPAKLRGTAAFAGGILLILF-RWP-------LIGFCVELYGILILFGDFL 104
                 3336669999*****.....99***********************************************.***.......******************* PP

        Got1 102 Pggrsalkkv 111
                  ++ +++  v
  EEA19851.1 105 VTIGQFVGGV 114
                 9999998766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (139 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       460  (0.0256568); expected 358.6 (0.02)
Passed bias filter:                      232  (0.0129399); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.27s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 966.36
//
Query:       EEA19852.1  [L=1002]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.9e-16   59.7   0.0    8.1e-16   58.6   0.0    1.6  1  AAA              ATPase family associated with various cellul
     0.0031   17.8   1.4       0.11   12.8   1.4    2.6  1  AAA_22           AAA domain
     0.0031   17.9   0.0     0.0075   16.7   0.0    1.6  1  AAA_16           AAA ATPase domain
  ------ inclusion threshold ------
      0.011   15.8   0.0      0.027   14.5   0.0    1.7  1  AAA_5            AAA domain (dynein-related subfamily)
      0.024   14.4   0.0      0.049   13.4   0.0    1.4  1  AAA_30           AAA domain
      0.028   14.5   0.0      0.068   13.3   0.0    1.6  1  Torsin           Torsin
      0.041   13.5   0.2       0.58    9.8   0.2    2.3  2  Drf_FH3          Diaphanous FH3 Domain
       0.05   14.3   0.2       0.14   12.8   0.2    1.7  1  Phage_int_SAM_2  Phage integrase, N-terminal
      0.059   13.7   0.0       0.15   12.4   0.0    1.6  1  AAA_19           AAA domain
      0.065   12.9   0.0       0.11   12.1   0.0    1.3  1  Sigma54_activat  Sigma-54 interaction domain
      0.071   13.3   0.1       0.35   11.0   0.1    2.2  1  AAA_33           AAA domain


Domain annotation for each model (and alignments):
>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.6   0.0     5e-19   8.1e-16       1     129 [.     778     896 ..     778     899 .. 0.91

  Alignments for each domain:
  == domain 1  score: 58.6 bits;  conditional E-value: 5e-19
                 EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTS..TSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTT CS
         AAA   1 vllyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakeka..kpsilfiDEidalaksrsgseseeeervvnqLlteldgvk 97 
                 +ll+G pGtGKT +a++va+ ++ +++++ + ++       +++++++++++a +      +++++DE+d + ++r + ++ +++ +v ++l++l+ ++
  EEA19852.1 778 ILLHGGPGTGKTFTAESVAELAEKPLYRVTCGDIG-----TKPEEVENYMESALHLGkiWDCVVLLDEADVFLQER-NLSDLQRNALVTVFLRVLEYYD 870
                 69********************************9.....789999999999877775545***************.7789999999*********999 PP

                 TSSSTEEEEEEESSGGGSTHHHHSTTSSEEEE CS
         AAA  98 kkeskvivigatnrpdkldpallrgRfdrkie 129
                       i+i+++nr+ +ld+a+  +R++  ++
  EEA19852.1 871 G-----ILILTSNRVGTLDEAFK-SRIQASLH 896
                 9.....*****************.9*987765 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.8   1.4   6.8e-05      0.11       7      51 ..     777     812 ..     771     866 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 6.8e-05
      AAA_22   7 ilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsst 51 
                  ++++G +GtGKT++++ ++e +         ++++++vt+   +
  EEA19852.1 777 TILLHGGPGTGKTFTAESVAELA---------EKPLYRVTCGDIG 812
                 689******************99.........7888888887655 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   4.6e-06    0.0075      21      52 ..     772     833 ..     766     930 .. 0.58

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 4.6e-06
      AAA_16  21 sgrpelvllsGesGvGKsslvrellralekd..............................g 52 
                 +g +  +ll+G +G+GK+  ++++++ +ek                               +
  EEA19852.1 772 KGNGLTILLHGGPGTGKTFTAESVAELAEKPlyrvtcgdigtkpeevenymesalhlgkiwD 833
                 466689*******************8887777655544444444444444444444444432 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.0   1.7e-05     0.027       2      62 ..     778     840 ..     777     911 .. 0.68

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 1.7e-05
                 EEEE--SSSSHHHHHHHGGGGBS--EEEEE--T.T--HHHHH--B--..........------ CS
       AAA_5   2 vlLvGppGtgKselaerlaaalnreveyvqltr.dtteedlkgrreik.ngttslvdsplvra 62 
                 +lL G pGtgK++ ae++a++ ++++  v + + +t++e++   +e +   ++ +   +l ++
  EEA19852.1 778 ILLHGGPGTGKTFTAESVAELAEKPLYRVTCGDiGTKPEEVENYMESAlHLGKIWDCVVLLDE 840
                 79********************88887777654378888887777755555555555555555 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0     3e-05     0.049      19      49 ..     776     806 ..     767     809 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 3e-05
      AAA_30  19 rvavltGpAGtGKttalkalreaweaaggrv 49 
                 ++ +l+G++GtGKt++ ++++e++e+  +rv
  EEA19852.1 776 LTILLHGGPGTGKTFTAESVAELAEKPLYRV 806
                 46689******************99876666 PP

>> Torsin  Torsin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   4.2e-05     0.068      46      75 ..     768     797 ..     732     808 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 4.2e-05
                 T-SS-SS-EEEEEEE-TTSSHHHHHHHHHH CS
      Torsin  46 enekpkkpLvlsfhGwtGtGknfvaeiiae 75 
                   e+    L++ +hG +GtGk f ae +ae
  EEA19852.1 768 MIEDKGNGLTILLHGGPGTGKTFTAESVAE 797
                 345566789****************99886 PP

>> Drf_FH3  Diaphanous FH3 Domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.2   0.00035      0.58      84     180 ..      90     187 ..      82     198 .. 0.89
   2 ?    0.4   0.0      0.25   4.1e+02      84     118 ..     434     466 ..     429     482 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00035
                 CSHHHHHHHHHHHHHHHHHHHHHHHHHT.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
     Drf_FH3  84 eneeLddqlqafeeerneDeeellerae.dktvdlddpeelfellknkvkdteaepyllsilqhlllirddeeekesylklleelvsqivlqrtkidp 180
                 e  +++++   f++  neD++e  +  + ++  +++d+ ++++l     ++   ++ +ls+ +h +l +d+++e     k l +++sq++ +  + ++
  EEA19852.1  90 EQTKVTKASSDFDDYYNEDYDEQGDNDNlTHLTHIEDNGRIYQLKDFAQQEILINDPFLSASKHTTLSEDRTSESGWNKKRLAAVLSQVSRHPPPAKN 187
                 56678888899*****************9****************99*******************************************99655444 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.25
                 CSHHHHHHHHHHHHHHHHHHHHHHHHHTXXXXXXX CS
     Drf_FH3  84 eneeLddqlqafeeerneDeeelleraedktvdld 118
                  ++e+++++q++++ +  D+++l  +++ +t +++
  EEA19852.1 434 ASDEMRRAIQNYLNRQP-DFKQLFPSFD-VTKEIS 466
                 689**********9999.*****99999.555555 PP

>> Phage_int_SAM_2  Phage integrase, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.2   8.7e-05      0.14      49      88 ..     924     963 ..     901     965 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 8.7e-05
  Phage_int_SAM_2  49 lKarHieayieerlaeeiskrtlqNemaalRsvlrkaGrk 88 
                      +    ie yi+e  ++e+  r ++N +++ R ++r+ Gr+
       EEA19852.1 924 IDFDDIECYISELAEQEMNGRQIRNSITTARQLARFKGRN 963
                      556679********************************96 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   9.4e-05      0.15      11      34 ..     776     799 ..     767     806 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 9.4e-05
      AAA_19  11 kvllvtaGpGtGKTrvlkhivall 34 
                  ++l+ +GpGtGKT + + + +l+
  EEA19852.1 776 LTILLHGGPGTGKTFTAESVAELA 799
                 57899**********998877665 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0     7e-05      0.11      22      62 ..     775     812 ..     755     827 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 7e-05
                      SS-EEEECSTTSSHHHHHHHHHHHSTTTTS-EEEEETTTS- CS
  Sigma54_activat  22 dlsvlitGesGtGKellaraiheaskrkekpfvavncaaip 62 
                       l++l++G  GtGK++ a+++ e  +   kp+ +v c++i 
       EEA19852.1 775 GLTILLHGGPGTGKTFTAESVAELAE---KPLYRVTCGDIG 812
                      489****************9987755...999999999983 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.1   0.00021      0.35       2      91 ..     778     912 ..     778     959 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00021
      AAA_33   2 vllvGlpGsGKstlaerllkklg..avllssdt..........................................lrrrlfgtdqqskt.......... 46 
                 +ll+G pG+GK++ ae++++      ++++  +                                          l            +          
  EEA19852.1 778 ILLHGGPGTGKTFTAESVAELAEkpLYRVTCGDigtkpeevenymesalhlgkiwdcvvlldeadvflqernlsdL------------Qrnalvtvflr 864
                 689**************96332244666665444666666666666666666666666655544444333332221............02223344444 PP

      AAA_33  47 ...dytrvldrlyqilnelarkalsagrnvildatnlsrrer.arflkl 91 
                    +y  +l  + +++ +++++a ++++++ l  +nl+r++r + +++l
  EEA19852.1 865 vleYYDGILILTSNRV-GTLDEAFKSRIQASLHYPNLNRSQRhKIWRNL 912
                 4435555666666666.77777777777777777777776664344444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1002 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       606  (0.0338); expected 358.6 (0.02)
Passed bias filter:                      513  (0.0286129); expected 358.6 (0.02)
Passed Vit filter:                        74  (0.00412739); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.78u 0.34s 00:00:01.12 Elapsed: 00:00:00.47
# Mc/sec: 6435.48
//
Query:       EEA19853.1  [L=373]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (373 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       463  (0.0258241); expected 358.6 (0.02)
Passed bias filter:                      410  (0.022868); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.47
# Mc/sec: 2373.35
//
Query:       EEA19854.1  [L=365]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.7e-11   43.8   0.0    7.9e-11   41.7   0.0    2.0  1  PNP_UDP_1  Phosphorylase superfamily


Domain annotation for each model (and alignments):
>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.7   0.0   4.4e-15   7.9e-11       2     220 ..      15     302 ..      14     314 .. 0.74

  Alignments for each domain:
  == domain 1  score: 41.7 bits;  conditional E-value: 4.4e-15
                 EEEEESSHHHHHHHHHHEEEEEEEEEE..TTEEEEEEEETTEEEEEEE--.SSHHHHHHHHHHHHHHHC.--SEEEEEEEEEES.....STTT-TT-EE CS
   PNP_UDP_1   2 iaiivgspgevellaespleetpfgre.grgfkfvtGtlkgkpvvivstG.iGkpnaavvaeirllkef.gvkaiiriGtaGgl.....npdlkvGDvv 92 
                 +a+i++++ e +++ +   e +p  ++      +++G+++ ++vvi+s   iG  +aa   +  ll +f +v+  + iG+ Gg+       d+++GDvv
  EEA19854.1  15 VACICPMGVEQAPVEALLDEIHPSLPTsLDKNSYTLGRMGIHNVVIASMPdIGNNSAA-SVANQLLNDFrSVRFSLLIGVGGGVpnvrnGIDIRLGDVV 112
                 89******888888888677777887788999**************99999*******.777777777846666699*******6664444577***** PP

                 EEEE......EEESSSCCGCCTHHCC....................................................TCCCCTTSSEE--HHHHHHHH CS
   PNP_UDP_1  93 ipdd......ainfdgrsplygpkee....................................................gqyfpdsydapadpelrallk 133
                 +++       +++fd + +l++ + e                                                    g             +  ++l+
  EEA19854.1 113 VSKPsglfggVVQFDRGKTLTNDRFErtgvldrppnillatvarlealhlrvdseipnhlqemiqkyprmkrgnyiyqG-------------SENDRLF 198
                 ****777777799*****99999999999************99998888888888888888886555554444433332.............3333333 PP

                 H....CHHTTT.......................TTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHT.T--EEEEEEEEETTTBE CS
   PNP_UDP_1 134 e....aaealg.......................ikvhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArel.gipfaairvvsdlaagg 204
                 +    +                            + +h+G++++++++  + + +++l ++l+++++eME+a +      +   p++++r++ d+a+ +
  EEA19854.1 199 QatyeH----TggqdcercdsakvlvreprpdinPVIHYGTIGSSNTVIKDAQTRDELRNTLNIQCLEMEAAGL------MeSFPCLVVRGICDYADSH 287
                 332221....133334444455566666688888************************************9765......4259999999999966664 PP

                 TTCTCH.HCCCHHHHH CS
   PNP_UDP_1 205 adaeatheeveefaqe 220
                   + ++   + ++a++
  EEA19854.1 288 KNKRWQ-PYAAAVAAA 302
                 444443.333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (365 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       383  (0.021362); expected 358.6 (0.02)
Passed bias filter:                      367  (0.0204696); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2559.94
//
Query:       EEA19855.1  [L=264]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.3e-25   87.4   0.2    1.6e-12   47.8   0.0    2.4  2  Ank_2     Ankyrin repeats (3 copies)
      1e-23   83.4   1.2    3.7e-09   36.9   0.0    4.2  5  Ank_4     Ankyrin repeats (many copies)
    1.1e-21   74.5   2.7    0.00036   20.7   0.0    6.1  6  Ank_3     Ankyrin repeat
    4.8e-20   71.0   2.6     0.0017   18.7   0.0    5.9  5  Ank       Ankyrin repeat
    2.1e-14   53.4   0.2    1.1e-05   25.6   0.0    4.3  4  Ank_5     Ankyrin repeats (many copies)


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.8   0.0   4.5e-16   1.6e-12       6      80 ..       8      85 ..       2      87 .. 0.86
   2 !   37.5   0.1   7.6e-13   2.7e-09       1      80 [.      95     185 ..      94     187 .. 0.84

  Alignments for each domain:
  == domain 1  score: 47.8 bits;  conditional E-value: 4.5e-16
       Ank_2  6 kn.gnlelvklLl.egadpnkngktaLhyAakngnleivklLleh.ad.....ndgrtpLhyAarsghleivklLlekgadin 80
                 +     +vklL+ +ga+++     aL  A+++ +++i++lLle+ a+     ++ +tpL++A+++ ++++v+lLl++gadi+
  EEA19855.1  8 ADiR---IVKLLMdNGARAD--SPMALCSAVRSKDIDIIRLLLENgANpnherYQDETPLQIACFNEQPNVVELLLQYGADIK 85
                4334...9*****9999987..58********************8855547778899************************96 PP

  == domain 2  score: 37.5 bits;  conditional E-value: 7.6e-13
       Ank_2   1 LhlAak.ngnlelvklLl.egadpn.k...ngktaLhyAakngnleivklLleh.ad.....ndgrtpLhyAarsghleivklLlekgadin 80 
                 L+lAa  +g+ e++++L+ +gad+n     +g t Lh+Aa+ g++++v +L+++ ad        +++L +A  + +++i+ lLl+kgad++
  EEA19855.1  95 LQLAAAtFGSVETLRILIaNGADVNqRggaFG-TSLHAAAHFGDVDMVDYLIAQgADihaegLMFKSVLRHALGNAYTDIFVLLLKKGADME 185
                 56788846*99**************6256798.*******************9884444335445699****99999********99**986 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.28     1e+03      11      26 ..       7      22 ..       1      26 [. 0.78
   2 !   35.2   0.0   3.5e-12   1.3e-08       4      55 .]      28      78 ..      27      78 .. 0.95
   3 !   36.9   0.0     1e-12   3.7e-09       7      55 .]      98     145 ..      94     145 .. 0.91
   4 !   22.7   0.1   3.1e-08   0.00011       3      54 ..     127     177 ..     126     178 .. 0.74
   5 ?   -0.6   0.0      0.61   2.2e+03       5      27 ..     162     184 ..     159     195 .. 0.66

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.28
       Ank_4 11 sgrlelvrlLlekgad 26
                s ++++v+lL ++ga 
  EEA19855.1  7 SADIRIVKLLMDNGAR 22
                778999****999986 PP

  == domain 2  score: 35.2 bits;  conditional E-value: 3.5e-12
       Ank_4  4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55
                aL +a+ s +++++rlLle+ga++n+    ++et+l+iA+ ++++++++lLl
  EEA19855.1 28 ALCSAVRSKDIDIIRLLLENGANPNHE-RYQDETPLQIACFNEQPNVVELLL 78
                5889999*******************5.99999******************8 PP

  == domain 3  score: 36.9 bits;  conditional E-value: 1e-12
       Ank_4   7 yaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +aa +g +e++r+L+++gad+n +  +   t lh Aa +g+v+++ +L+
  EEA19855.1  98 AAATFGSVETLRILIANGADVNQR-GGAFGTSLHAAAHFGDVDMVDYLI 145
                 4555********************.99999******************8 PP

  == domain 4  score: 22.7 bits;  conditional E-value: 3.1e-08
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGe...talhiAakrgnveilklL 54 
                 t Lh+aa++g++++v++L+++gadi+a    +G+   + l +A+ + + +i+ lL
  EEA19855.1 127 TSLHAAAHFGDVDMVDYLIAQGADIHA----EGLmfkSVLRHALGNAYTDIFVLL 177
                 67**********************987....344333466666666666666555 PP

  == domain 5  score: -0.6 bits;  conditional E-value: 0.61
       Ank_4   5 LhyaaisgrlelvrlLlekgadi 27 
                 L +a     +++  lLl kgad 
  EEA19855.1 162 LRHALGNAYTDIFVLLLKKGADM 184
                 55555566777778899899885 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0      0.43   1.5e+03      12      27 ..       7      21 ..       2      24 .. 0.71
   2 !   14.2   0.1   1.4e-05      0.05       9      31 .]      32      53 ..      27      53 .. 0.93
   3 !   20.4   0.0   1.3e-07   0.00046       3      29 ..      59      84 ..      57      86 .. 0.95
   4 !    9.2   0.0   0.00057         2       9      30 ..      99     119 ..      94     120 .. 0.89
   5 !   20.7   0.0     1e-07   0.00036       4      31 .]     127     153 ..     126     153 .. 0.95
   6 ?    3.2   0.0     0.053   1.9e+02       4      28 ..     160     183 ..     159     184 .. 0.87

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.43
       Ank_3 12 sgnleivkfLlenkga 27
                s+++ ivk+L + +ga
  EEA19855.1  7 SADIRIVKLLMD-NGA 21
                445557****99.787 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 1.4e-05
       Ank_3  9 AarsgnleivkfLlenkgadvna 31
                A+rs +++i+++Lle +ga++n+
  EEA19855.1 32 AVRSKDIDIIRLLLE-NGANPNH 53
                99*************.8****96 PP

  == domain 3  score: 20.4 bits;  conditional E-value: 1.3e-07
       Ank_3  3 etpLhlAarsgnleivkfLlenkgadv 29
                etpL +A+ +  +++v++Ll+ +gad+
  EEA19855.1 59 ETPLQIACFNEQPNVVELLLQ-YGADI 84
                8********************.****8 PP

  == domain 4  score: 9.2 bits;  conditional E-value: 0.00057
       Ank_3   9 AarsgnleivkfLlenkgadvn 30 
                 Aa +g++e ++ L+  +gadvn
  EEA19855.1  99 AATFGSVETLRILIA-NGADVN 119
                 9999***99******.8****9 PP

  == domain 5  score: 20.7 bits;  conditional E-value: 1e-07
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadvna 31 
                 t Lh Aa++g++++v++L+   gad++a
  EEA19855.1 127 TSLHAAAHFGDVDMVDYLIA-QGADIHA 153
                 89******************.9***985 PP

  == domain 6  score: 3.2 bits;  conditional E-value: 0.053
       Ank_3   4 tpLhlAarsgnleivkfLlenkgad 28 
                 + L +A+ ++ ++i  +Ll+ kgad
  EEA19855.1 160 SVLRHALGNAYTDIFVLLLK-KGAD 183
                 56889999999999999999.9998 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.5   2.3e-05     0.083       6      29 ..      29      53 ..       2      55 .. 0.89
   2 !   18.7   0.0   4.7e-07    0.0017       4      27 ..      60      84 ..      58      86 .. 0.92
   3 !   13.2   0.0   2.6e-05     0.092       5      30 ..      94     121 ..      92     122 .. 0.91
   4 !   16.6   0.1   2.3e-06    0.0082       4      29 ..     127     153 ..     127     155 .. 0.93
   5 ?    0.1   0.0      0.38   1.4e+03      15      26 ..     171     183 ..     161     186 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 2.3e-05
                HHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank  6 LHlAatngkkriiklLL.hGAnlna 29
                L  A++ ++ +ii+lLL +GAn+n 
  EEA19855.1 29 LCSAVRSKDIDIIRLLLeNGANPNH 53
                55577777789******99****96 PP

  == domain 2  score: 18.7 bits;  conditional E-value: 4.7e-07
                BHHHHHHHHTTHHHHHHHH.TTTST CS
         Ank  4 TPLHlAatngkkriiklLL.hGAnl 27
                TPL +A+ n ++++++lLL +GA++
  EEA19855.1 60 TPLQIACFNEQPNVVELLLqYGADI 84
                *******9999********77**97 PP

  == domain 3  score: 13.2 bits;  conditional E-value: 2.6e-05
                 HHHHHH.HHTTHHHHHHHH.TTTSTTCB CS
         Ank   5 PLHlAa.tngkkriiklLL.hGAnlnal 30 
                 PL lAa t+g+++ ++ L+ +GA++n++
  EEA19855.1  94 PLQLAAaTFGSVETLRILIaNGADVNQR 121
                 8998888************99*****86 PP

  == domain 4  score: 16.6 bits;  conditional E-value: 2.3e-06
                 BHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnlna 29 
                 T LH Aa++g+++++ +L+ +GA+++a
  EEA19855.1 127 TSLHAAAHFGDVDMVDYLIaQGADIHA 153
                 56*****************99***998 PP

  == domain 5  score: 0.1 bits;  conditional E-value: 0.38
                 HHHHHHHH.TTTS CS
         Ank  15 kriiklLL.hGAn 26 
                 ++i  lLL +GA+
  EEA19855.1 171 TDIFVLLLkKGAD 183
                 5688899988*99 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.0   3.1e-09   1.1e-05       1      56 []      44      98 ..      44      98 .. 0.98
   2 !    6.9   0.0    0.0023       8.1      23      45 ..      99     121 ..      99     124 .. 0.93
   3 !   19.5   0.2   2.5e-07   0.00091       1      43 [.     111     152 ..     111     154 .. 0.84
   4 ?    0.1   0.0       0.3   1.1e+03      22      42 ..     164     184 ..     159     195 .. 0.76

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 3.1e-09
       Ank_5  1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56
                Lle+g a++n+++   +tpL +A+ +  ++vv+lLl +gad++   +r++ +l+lA
  EEA19855.1 44 LLENG-ANPNHERYQDETPLQIACFNEQPNVVELLLQYGADIKSGGGRYEIPLQLA 98
                89***.************************************************98 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0023
       Ank_5  23 AakygaadvvrlLlargadlnlt 45 
                 Aa  g+ + +r+L+a+gad n++
  EEA19855.1  99 AATFGSVETLRILIANGADVNQR 121
                 8999*****************97 PP

  == domain 3  score: 19.5 bits;  conditional E-value: 2.5e-07
       Ank_5   1 Llehgpadvnrldgggn.tpLhvAakygaadvvrlLlargadln 43 
                 L+++g advn + g  + t Lh Aa+ g  d+v +L+a gad+ 
  EEA19855.1 111 LIANG-ADVNQRGGA-FgTSLHAAAHFGDVDMVDYLIAQGADIH 152
                 78999.888775443.35********************999986 PP

  == domain 4  score: 0.1 bits;  conditional E-value: 0.3
       Ank_5  22 vAakygaadvvrlLlargadl 42 
                 +A  + + d++ lLl+ gad 
  EEA19855.1 164 HALGNAYTDIFVLLLKKGADM 184
                 566778899999999999985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (264 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       368  (0.0205254); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 1724.25
//
Query:       EEA19856.1  [L=1166]
Description: NACHT domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-38  131.7   8.1    7.6e-11   42.4   0.0    6.2  7  Ank_2         Ankyrin repeats (3 copies)
    1.9e-28   98.5   2.1    2.6e-06   27.8   0.0    8.6 10  Ank_4         Ankyrin repeats (many copies)
    9.5e-27   90.1   2.8     0.0071   16.8   0.0   11.3 11  Ank_3         Ankyrin repeat
    1.3e-24   85.5   9.0     0.0033   17.8   0.0    9.7  9  Ank           Ankyrin repeat
    2.7e-20   72.2   3.3     0.0046   17.2   0.0    8.7  9  Ank_5         Ankyrin repeats (many copies)
      1e-07   32.0   0.0    2.8e-07   30.6   0.0    1.7  1  NACHT         NACHT domain
    4.9e-06   26.1   0.5    1.4e-05   24.6   0.1    2.0  2  Helo_like_N   Fungal N-terminal domain of STAND proteins
    2.7e-05   24.4   0.1    0.00011   22.5   0.0    2.1  1  AAA_22        AAA domain
    0.00014   21.9   1.5       0.17   11.9   0.5    3.5  2  AAA_14        AAA domain
    0.00014   22.2   0.0      0.013   15.9   0.0    2.7  2  RNA_helicase  RNA helicase
    0.00015   22.2   0.1      0.001   19.5   0.0    2.2  2  AAA_16        AAA ATPase domain
  ------ inclusion threshold ------
      0.014   16.0   0.0       0.03   14.8   0.0    1.6  1  AAA_18        AAA domain
      0.018   14.2   0.1      0.051   12.8   0.1    1.7  1  NB-ARC        NB-ARC domain
      0.025   15.0   0.0      0.063   13.7   0.0    1.8  1  AAA           ATPase family associated with various cellular 
      0.044   13.8   0.0      0.098   12.7   0.0    1.5  1  TsaE          Threonylcarbamoyl adenosine biosynthesis protei
      0.069   13.1   0.0       0.14   12.0   0.0    1.5  1  ATPase_2      ATPase domain predominantly from Archaea
       0.11   12.0   0.0       0.28   10.7   0.0    1.6  1  AAA_25        AAA domain


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0      0.23   2.4e+02      27      79 ..     704     770 ..     694     774 .. 0.76
   2 ?    5.7   0.0     0.021        22      38      81 ..     756     804 ..     754     806 .. 0.76
   3 !   22.8   0.0   9.7e-08    0.0001       1      80 [.     780     888 ..     780     890 .. 0.84
   4 !   29.0   0.0   1.1e-09   1.2e-06      27      80 ..     901     955 ..     890     958 .. 0.90
   5 !   42.4   0.0   7.2e-14   7.6e-11       1      81 [.     932    1024 ..     932    1026 .. 0.84
   6 !   39.0   0.6   8.8e-13   9.3e-10       1      82 [.     967    1058 ..     967    1059 .. 0.85
   7 !   34.9   0.2   1.6e-11   1.7e-08       3      82 ..    1002    1091 ..    1000    1092 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.23
       Ank_2  27 ktaLhyAakngnleivklLleh..adndgrtpLhyAarsg............hleivklLlekgadi 79 
                 k++L +Aa +g + ++k + e   +d + + +L  A r +            +l++ klL+e+gad+
  EEA19856.1 704 KSPLNTAAAYGFIPLLKRIFESgeIDITSNAVLNDALRASylgvtfprpprpNLDVTKLLIEHGADF 770
                 5788888888877777777776677777777888888874444777777777889999999999986 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.021
       Ank_2  38 nleivklLleh.ad.....ndgr.tpLhyAarsghleivklLlekgadinl 81 
                 nl++ klL+eh ad     +  + + Lh A+ +g ++++k  le g+d+n 
  EEA19856.1 756 NLDVTKLLIEHgADfasdsR--YaNTLHGASYYGIYDLMKAELEAGVDVNS 804
                 568899****9944544333..3366*****99******988888999986 PP

  == domain 3  score: 22.8 bits;  conditional E-value: 9.7e-08
       Ank_2   1 LhlAakngnlelvklLl.egadpn.k..ngktaLhyAakngnl.e..................ivklLleh.ad.....ndgrtpLhyAarsghleivk 70 
                 Lh A+++g ++l+k  l +g+d+n +  +  +aL +A+ + +  +                  ++k+Lleh a+      +  tpL+++++ g + +vk
  EEA19856.1 780 LHGASYYGIYDLMKAELeAGVDVNsQggKYASALDAAIAGRHSlNflqggtrlgqyletiepsCIKTLLEHdANpnvcrGSSGTPLMLSSSIGDIVVVK 878
                 899***997799999999*****97466779999999887654359999999*******99999******99554464423449*****977******* PP

       Ank_2  71 lLlekgadin 80 
                 +Ll +gad+n
  EEA19856.1 879 ILLAHGADPN 888
                 ********98 PP

  == domain 4  score: 29.0 bits;  conditional E-value: 1.1e-09
       Ank_2  27 ktaLhyAakngnleivklLleh.adndgrtpLhyAarsghleivklLlekgadin 80 
                 ++ L  A+ + +l +vklL+eh a  +    L +A++s++l+ivk+Lle+ga++n
  EEA19856.1 901 RSCLSSACYSKDLRVVKLLVEHgASVHSSCSLAVACWSSQLDIVKYLLENGASPN 955
                 789999****************98888899**********************998 PP

  == domain 5  score: 42.4 bits;  conditional E-value: 7.2e-14
       Ank_2    1 LhlAakngnlelvklLl.egadpn..k...ngktaLhyAakngnleivklLleh.ad.....ndgrtpLhyAarsghleivklLlekgadinl 81  
                  L +A+ + +l++vk+Ll +ga pn  +   +  ++L++A++n ++ iv+lLl++ ad     ++  +pL  Aa  g+  i ++L+ekg+++n+
  EEA19856.1  932 LAVACWSSQLDIVKYLLeNGASPNgsNdecDVGSPLQIACSNSSEAIVELLLKYgADvhlgrSHAGSPLNEAAIAGSVSITNMLIEKGVNVNM 1024
                  67899997799******9998888862466556**********9999******88554455566669***********************997 PP

  == domain 6  score: 39.0 bits;  conditional E-value: 8.8e-13
       Ank_2    1 LhlAakngnlelvklLl.egadpn...kngktaLhyAakngnleivklLleh...ad...ndgrtpLhyAarsghleivklLlekgadinlk 82  
                  L++A++n +  +v+lLl +gad++   +   ++L  Aa++g++ i  +L+e+   ++    +  t+L++Aa  g +++v+ L+ +ga++n++
  EEA19856.1  967 LQIACSNSSEAIVELLLkYGADVHlgrSHAGSPLNEAAIAGSVSITNMLIEKgvnVNmvaGHHGTALQAAANMGEIDVVECLIHNGANVNIQ 1058
                  7899**98778************98754556********************88554465333449******88**********99****986 PP

  == domain 7  score: 34.9 bits;  conditional E-value: 1.6e-11
       Ank_2    3 lAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh...ad.ndgr..tpLhyAarsghleivklLlekgadinlk 82  
                   Aa  g+ ++ + L+ +g+++n     + taL++Aa  g +++v+ L+ +   ++ + g   t+L++A ++ h ++v lLl +gad+++k
  EEA19856.1 1002 EAAIAGSVSITNMLIeKGVNVNmvAgHHGTALQAAANMGEIDVVECLIHNganVNiQCGFfkTALQAAFSWPHVNTVTLLLRSGADVDVK 1091
                  699999999******99999998636667**********9999*****76855447556556*******************99****987 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       9.3   9.8e+03       7      27 ..     709     730 ..     705     734 .. 0.74
   2 ?    3.8   0.0     0.089        94      13      28 ..     756     771 ..     750     781 .. 0.82
   3 ?    3.2   0.0      0.13   1.4e+02       5      47 ..     780     821 ..     776     827 .. 0.78
   4 !   12.6   0.0   0.00015      0.16      16      55 .]     843     881 ..     840     881 .. 0.94
   5 ?    1.0   0.0      0.65   6.9e+02      16      28 ..     876     888 ..     874     888 .. 0.93
   6 !   12.8   0.1   0.00013      0.14       2      30 ..     901     929 ..     901     937 .. 0.91
   7 !   27.8   0.0   2.5e-09   2.6e-06       9      55 .]     934     983 ..     927     983 .. 0.89
   8 !   19.1   0.0   1.4e-06    0.0015       4      55 .]     999    1049 ..     996    1049 .. 0.92
   9 !   21.0   0.1   3.5e-07   0.00037       2      55 .]    1030    1082 ..    1029    1082 .. 0.94
  10 !    6.9   0.0    0.0094       9.9       3      35 ..    1064    1095 ..    1063    1101 .. 0.86

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 9.3
       Ank_4   7 yaaisgrlelvrlLlekg.adi 27 
                  aa++g ++l+++++e+g +di
  EEA19856.1 709 TAAAYGFIPLLKRIFESGeIDI 730
                 6777888899999999975776 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.089
       Ank_4  13 rlelvrlLlekgadin 28 
                 +l++ +lL+e+gad  
  EEA19856.1 756 NLDVTKLLIEHGADFA 771
                 89************64 PP

  == domain 3  score: 3.2 bits;  conditional E-value: 0.13
       Ank_4   5 LhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgn 47 
                 Lh a ++g ++l +  le g+d+n q  +   +al+ A+ + +
  EEA19856.1 780 LHGASYYGIYDLMKAELEAGVDVNSQ-GGKYASALDAAIAGRH 821
                 67777777788888889*********.777779***9997765 PP

  == domain 4  score: 12.6 bits;  conditional E-value: 0.00015
       Ank_4  16 lvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +++ Lle++a++n +  +s  t+l    ++g++ ++k Ll
  EEA19856.1 843 CIKTLLEHDANPNVC-RGSSGTPLMLSSSIGDIVVVKILL 881
                 89************9.****************99999886 PP

  == domain 5  score: 1.0 bits;  conditional E-value: 0.65
       Ank_4  16 lvrlLlekgadin 28 
                 +v++Ll++gad+n
  EEA19856.1 876 VVKILLAHGADPN 888
                 699********98 PP

  == domain 6  score: 12.8 bits;  conditional E-value: 0.00013
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaq 30 
                 +++L +a++s +l++v+lL+e+ga+++ +
  EEA19856.1 901 RSCLSSACYSKDLRVVKLLVEHGASVHSS 929
                 5899*********************9876 PP

  == domain 7  score: 27.8 bits;  conditional E-value: 2.5e-09
       Ank_4   9 ai..sgrlelvrlLlekgadinaqdnrsGe..talhiAakrgnveilklLl 55 
                 ++  s++l++v++Lle+ga++n + n++++  ++l+iA+++++  i++lLl
  EEA19856.1 934 VAcwSSQLDIVKYLLENGASPNGS-NDECDvgSPLQIACSNSSEAIVELLL 983
                 335599*****************9.99999889*****************8 PP

  == domain 8  score: 19.1 bits;  conditional E-value: 1.4e-06
       Ank_4    4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  +L  aai+g + +   L+ekg+++n++  + + tal+ Aa +g +++++ L+
  EEA19856.1  999 PLNEAAIAGSVSITNMLIEKGVNVNMV-AGHHGTALQAAANMGEIDVVECLI 1049
                  66679**********************.66699****************997 PP

  == domain 9  score: 21.0 bits;  conditional E-value: 3.5e-07
       Ank_4    2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                   taL +aa++g +++v+ L+ +ga++n q  +   tal+ A ++ +v+ + lLl
  EEA19856.1 1030 GTALQAAANMGEIDVVECLIHNGANVNIQ-CGFFKTALQAAFSWPHVNTVTLLL 1082
                  589**************************.88888***************9997 PP

  == domain 10  score: 6.9 bits;  conditional E-value: 0.0094
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsG 35  
                  taL +a++  ++ +v lLl +gad++  ++  G
  EEA19856.1 1064 TALQAAFSWPHVNTVTLLLRSGADVDVKSPY-G 1095
                  78999**************99*****98665.4 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.0     0.045        47       4      29 ..     705     730 ..     703     732 .. 0.89
   2 ?    1.7   0.0      0.53   5.6e+02      14      29 ..     756     770 ..     752     772 .. 0.84
   3 ?    0.4   0.0       1.5   1.5e+03       9      30 ..     783     803 ..     780     804 .. 0.86
   4 ?    0.4   0.0       1.4   1.5e+03      17      30 ..     843     855 ..     835     856 .. 0.83
   5 !   10.9   0.0   0.00056      0.59       4      30 ..     863     888 ..     862     889 .. 0.96
   6 !    8.8   0.0    0.0026       2.7       3      30 ..     901     927 ..     899     928 .. 0.92
   7 !    7.4   0.0    0.0077       8.1       8      30 ..     934     955 ..     929     956 .. 0.83
   8 !   16.8   0.0   6.7e-06    0.0071       4      30 ..     965     990 ..     964     991 .. 0.95
   9 !   12.8   0.0   0.00013      0.14       4      30 ..     998    1023 ..     997    1024 .. 0.96
  10 !   10.3   0.1   0.00086      0.91       4      31 .]    1031    1057 ..    1028    1057 .. 0.94
  11 ?   -0.6   0.0       3.1   3.3e+03       5      30 ..    1065    1089 ..    1063    1090 .. 0.73

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.045
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadv 29 
                 +pL +Aa +g ++++k ++e   +d+
  EEA19856.1 705 SPLNTAAAYGFIPLLKRIFESGEIDI 730
                 8*****************99777776 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.53
       Ank_3  14 nleivkfLlenkgadv 29 
                 nl++ k+L+e +gad+
  EEA19856.1 756 NLDVTKLLIE-HGADF 770
                 567899****.9**97 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 1.5
       Ank_3   9 AarsgnleivkfLlenkgadvn 30 
                 A  +g ++++k+ le  g+dvn
  EEA19856.1 783 ASYYGIYDLMKAELE-AGVDVN 803
                 77789999*******.9****9 PP

  == domain 4  score: 0.4 bits;  conditional E-value: 1.4
       Ank_3  17 ivkfLlenkgadvn 30 
                  +k Lle + a++n
  EEA19856.1 843 CIKTLLE-HDANPN 855
                 499****.9***99 PP

  == domain 5  score: 10.9 bits;  conditional E-value: 0.00056
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadvn 30 
                 tpL+l  + g++ +vk Ll  +gad+n
  EEA19856.1 863 TPLMLSSSIGDIVVVKILLA-HGADPN 888
                 9*******************.9****9 PP

  == domain 6  score: 8.8 bits;  conditional E-value: 0.0026
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvn 30 
                 ++ L  A+ s +l +vk+L+e +ga v+
  EEA19856.1 901 RSCLSSACYSKDLRVVKLLVE-HGASVH 927
                 78999****************.9*9986 PP

  == domain 7  score: 7.4 bits;  conditional E-value: 0.0077
       Ank_3   8 lAarsgnleivkfLlenkgadvn 30 
                 +A+ s  l+ivk+Lle +ga +n
  EEA19856.1 934 VACWSSQLDIVKYLLE-NGASPN 955
                 677778899*******.8**999 PP

  == domain 8  score: 16.8 bits;  conditional E-value: 6.7e-06
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadvn 30 
                 +pL +A+++ + +iv++Ll+ +gadv+
  EEA19856.1 965 SPLQIACSNSSEAIVELLLK-YGADVH 990
                 79******************.****97 PP

  == domain 9  score: 12.8 bits;  conditional E-value: 0.00013
       Ank_3    4 tpLhlAarsgnleivkfLlenkgadvn 30  
                  +pL +Aa +g+++i  +L+e kg++vn
  EEA19856.1  998 SPLNEAAIAGSVSITNMLIE-KGVNVN 1023
                  7*******************.9****9 PP

  == domain 10  score: 10.3 bits;  conditional E-value: 0.00086
       Ank_3    4 tpLhlAarsgnleivkfLlenkgadvna 31  
                  t+L  Aa  g +++v+ L+  +ga+vn+
  EEA19856.1 1031 TALQAAANMGEIDVVECLIH-NGANVNI 1057
                  99******************.8****97 PP

  == domain 11  score: -0.6 bits;  conditional E-value: 3.1
       Ank_3    5 pLhlAarsgnleivkfLlenkgadvn 30  
                  +L  A +  +++ v +Ll+  gadv+
  EEA19856.1 1065 ALQAAFSWPHVNTVTLLLR-SGADVD 1089
                  5555556666767999***.8***98 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0     0.071        75      14      26 ..     756     769 ..     741     774 .. 0.86
   2 ?    4.9   0.0     0.039        41      15      29 ..     841     856 ..     811     857 .. 0.72
   3 !   17.8   0.0   3.1e-06    0.0033       4      29 ..     863     889 ..     863     890 .. 0.95
   4 !   10.7   0.0   0.00054      0.57       4      28 ..     902     927 ..     900     931 .. 0.86
   5 !    7.9   0.0    0.0043       4.6       8      28 ..     934     955 ..     927     959 .. 0.81
   6 !   13.5   0.0   7.4e-05     0.078       4      28 ..     965     990 ..     965     992 .. 0.92
   7 ?    3.4   0.0      0.11   1.1e+02       5      29 ..     999    1024 ..     998    1026 .. 0.84
   8 !   11.4   0.1   0.00033      0.35       4      30 ..    1031    1058 ..    1031    1059 .. 0.88
   9 ?    6.3   0.0     0.014        15       4      30 ..    1064    1091 ..    1063    1092 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.071
                 THHHHHHHH.TTTS CS
         Ank  14 kkriiklLL.hGAn 26 
                 +++++klL+ hGA+
  EEA19856.1 756 NLDVTKLLIeHGAD 769
                 578*********98 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.039
                 HHHHHHHH.TTTSTTC CS
         Ank  15 kriiklLL.hGAnlna 29 
                 +++ik LL h An+n 
  EEA19856.1 841 PSCIKTLLeHDANPNV 856
                 78************95 PP

  == domain 3  score: 17.8 bits;  conditional E-value: 3.1e-06
                 BHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnlna 29 
                 TPL+l +++g+  ++k LL hGA++n 
  EEA19856.1 863 TPLMLSSSIGDIVVVKILLaHGADPNF 889
                 9****99******************95 PP

  == domain 4  score: 10.7 bits;  conditional E-value: 0.00054
                 BHHHHHHHHTTHHHHHHHH.TTTSTT CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnln 28 
                 ++L  A++ +++r++klL+ hGA+++
  EEA19856.1 902 SCLSSACYSKDLRVVKLLVeHGASVH 927
                 56888998888************986 PP

  == domain 5  score: 7.9 bits;  conditional E-value: 0.0043
                 HHHHHTTHHHHHHHH.TTTSTT CS
         Ank   8 lAatngkkriiklLL.hGAnln 28 
                 +A++  +++i+k+LL +GA++n
  EEA19856.1 934 VACWSSQLDIVKYLLeNGASPN 955
                 466556688******99***99 PP

  == domain 6  score: 13.5 bits;  conditional E-value: 7.4e-05
                 BHHHHHHHHTTHHHHHHHH.TTTSTT CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnln 28 
                 +PL +A++n ++ i++lLL +GA+++
  EEA19856.1 965 SPLQIACSNSSEAIVELLLkYGADVH 990
                 69*****9999********88***96 PP

  == domain 7  score: 3.4 bits;  conditional E-value: 0.11
                  HHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank    5 PLHlAatngkkriiklLL.hGAnlna 29  
                  PL  Aa  g+++i+ +L+ +G n+n+
  EEA19856.1  999 PLNEAAIAGSVSITNMLIeKGVNVNM 1024
                  67767768999*******99****97 PP

  == domain 8  score: 11.4 bits;  conditional E-value: 0.00033
                  BHHHHHHHHTTHHHHHHHH.TTTSTTCB CS
         Ank    4 TPLHlAatngkkriiklLL.hGAnlnal 30  
                  T+L  Aa+ g  ++++ L+ +GAn+n++
  EEA19856.1 1031 TALQAAANMGEIDVVECLIhNGANVNIQ 1058
                  99999**778888******559****97 PP

  == domain 9  score: 6.3 bits;  conditional E-value: 0.014
                  BHHHHHHHHTTHHHHHHHH.TTTSTTCB CS
         Ank    4 TPLHlAatngkkriiklLL.hGAnlnal 30  
                  T+L  A +  +++ + lLL +GA+++ +
  EEA19856.1 1064 TALQAAFSWPHVNTVTLLLrSGADVDVK 1091
                  6777654788999******99***9865 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.0      0.52   5.5e+02      18      36 ..     705     723 ..     696     730 .. 0.88
   2 !    7.4   0.0    0.0053       5.6       2      54 ..     764     814 ..     763     816 .. 0.79
   3 !   17.2   0.0   4.4e-06    0.0046       1      43 [.     847     888 ..     847     889 .. 0.89
   4 ?    2.4   0.0      0.19     2e+02      11      42 ..     901     926 ..     894     931 .. 0.83
   5 !   15.7   0.0   1.4e-05     0.014       1      49 [.     919     961 ..     919     970 .. 0.82
   6 !    8.5   0.0    0.0023       2.5      18      53 ..     965    1000 ..     958    1003 .. 0.81
   7 !   13.9   0.1   4.9e-05     0.052       1      54 [.     982    1034 ..     982    1036 .. 0.88
   8 !    8.0   0.1    0.0035       3.7       1      54 [.    1015    1067 ..    1015    1069 .. 0.93
   9 ?    5.2   0.0     0.026        27       1      54 [.    1048    1100 ..    1048    1102 .. 0.94

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.52
       Ank_5  18 tpLhvAakygaadvvrlLl 36 
                 +pL++Aa yg  +++++++
  EEA19856.1 705 SPLNTAAAYGFIPLLKRIF 723
                 79**********9999988 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0053
       Ank_5   2 lehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltald 54 
                 +ehg ad  ++d +  + Lh A++yg  d+++  l+ g+d n + + + +ald
  EEA19856.1 764 IEHG-ADF-ASDSRYANTLHGASYYGIYDLMKAELEAGVDVNSQGGKYASALD 814
                 6666.222.33333349**************************9999999998 PP

  == domain 3  score: 17.2 bits;  conditional E-value: 4.4e-06
       Ank_5   1 Llehg.padvnrldgggntpLhvAakygaadvvrlLlargadln 43 
                 Lleh+ + +v+r   g  tpL+++++ g   vv++Lla+gad+n
  EEA19856.1 847 LLEHDaNPNVCRGSSG--TPLMLSSSIGDIVVVKILLAHGADPN 888
                 89***77777776666..************************98 PP

  == domain 4  score: 2.4 bits;  conditional E-value: 0.19
       Ank_5  11 rldgggntpLhvAakygaadvvrlLlargadl 42 
                 r      ++L  A++   ++vv+lL+++ga+ 
  EEA19856.1 901 R------SCLSSACYSKDLRVVKLLVEHGASV 926
                 4......78999****************9976 PP

  == domain 5  score: 15.7 bits;  conditional E-value: 1.4e-05
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrG 49 
                 L+ehg a+v  ++      L vA++   +d+v++Ll++ga++n  ++++
  EEA19856.1 919 LVEHG-ASVHSSC-----SLAVACWSSQLDIVKYLLENGASPNGSNDEC 961
                 67787.7777775.....89************************99987 PP

  == domain 6  score: 8.5 bits;  conditional E-value: 0.0023
       Ank_5   18 tpLhvAakygaadvvrlLlargadlnltdsrGltal 53  
                  +pL +A+++ +  +v+lLl++gad  l  s+  ++l
  EEA19856.1  965 SPLQIACSNSSEAIVELLLKYGADVHLGRSHAGSPL 1000
                  8999****88888888888******99998887777 PP

  == domain 7  score: 13.9 bits;  conditional E-value: 4.9e-05
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltald 54  
                  Ll++g adv   + +  +pL+ Aa +g+ ++ ++L++ g++ n+  ++  tal+
  EEA19856.1  982 LLKYG-ADVHLGRSHAGSPLNEAAIAGSVSITNMLIEKGVNVNMVAGHHGTALQ 1034
                  89999.77777777766***************************9999888886 PP

  == domain 8  score: 8.0 bits;  conditional E-value: 0.0035
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltald 54  
                  L+e+g ++vn   g+  t+L  Aa+ g  dvv+ L+ +ga+ n++++  +tal+
  EEA19856.1 1015 LIEKG-VNVNMVAGHHGTALQAAANMGEIDVVECLIHNGANVNIQCGFFKTALQ 1067
                  78999.99999999988******************************9999997 PP

  == domain 9  score: 5.2 bits;  conditional E-value: 0.026
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltald 54  
                  L+++g a+vn ++g+  t+L  A +  + + v lLl  gad +++  +G+t++d
  EEA19856.1 1048 LIHNG-ANVNIQCGFFKTALQAAFSWPHVNTVTLLLRSGADVDVKSPYGSTLVD 1100
                  78899.9****998888**********************************998 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.6   0.0   2.7e-10   2.8e-07       2     131 ..     253     397 ..     252     428 .. 0.70

  Alignments for each domain:
  == domain 1  score: 30.6 bits;  conditional E-value: 2.7e-10
                 CEEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC.-SEEEEEETTTTTTS-...-HCHHHCCCCTS--SSS-C......................CHHHHC CS
       NACHT   2 lvilqGeaGsGKTtLlqklalawaegklpqga.fklvFflslrelsrsgnarsladllfsqlpepaapvse......................vwavll 77 
                 l++l G  G+GKT+L   +a+++ +    + +   + F++++ ++++++ +  + + + +ql e + ++s                       v+ +++
  EEA19856.1 253 LLWLYGTVGCGKTILSSNVAEDLSTHSASEPNkALVYFYFKMDDTTKRSLE-NMLRAIIRQLFENSNCQSGalellyeqqnsqnsitetqllpVFREMA 350
                 79*********************9877655544799999999999999888.55555555555555666553444666666666666666666666666 PP

                 CSCCCEEEEEE-STT-SS-TCH.........HHHHHCTTTTT--EEEEEEECCC CS
       NACHT  78 elperlLlilDglDelvtdlgqkekqpvrtlLselirkkllpeasllltvrpra 131
                 +  +    +lD+lDe+++ ++     +  + ++++       + +lllt+r ++
  EEA19856.1 351 STLDNFYVVLDALDECQNRNDL---FNFLEEIGTWQDV----NIHLLLTSRDER 397
                 6666666**********98887...4444444444444....555666655554 PP

>> Helo_like_N  Fungal N-terminal domain of STAND proteins
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.6   0.1   1.3e-08   1.4e-05       1      59 [.       1      59 [.       1      74 [. 0.89
   2 ?   -3.7   0.0         6   6.4e+03     151     173 ..     291     313 ..     281     337 .. 0.66

  Alignments for each domain:
  == domain 1  score: 24.6 bits;  conditional E-value: 1.3e-08
  Helo_like_N  1 adplsiasgvlalvtfalqssksLyetvksfrsrdktvreLkeeleaLeevLesLeeva 59
                 +dplsi+++++a+++++   s+  ++ vks ++ + ++  L++e+  L+ vL++L++v 
   EEA19856.1  1 MDPLSISASIIAVIQITTVVSTHCMQYVKSAKNVEGELLILVREIGGLKIVLDTLKHVL 59
                 69******************************************************954 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 6
  Helo_like_N 151 ykeliedttsdLeehLedidekl 173
                  y ++  +t+  Le+ L+ i ++l
   EEA19856.1 291 YFKMDDTTKRSLENMLRAIIRQL 313
                  55566667777777777766555 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5   0.0     1e-07   0.00011       5     121 ..     251     385 ..     247     397 .. 0.65

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 1e-07
      AAA_22   5 agilvvtGesGtGKTtllrrlleqldeeakaeeerpevv...fvtlpsstsskdllrellralglelka..................erlsseelleal 82 
                  ++l ++G +G+GKT l  +++e l  +++ e +++ v+   +++ + + s++++lr++ r+l ++ +                    + ++  +++ +
  EEA19856.1 251 GSLLWLYGTVGCGKTILSSNVAEDLSTHSASEPNKALVYfyfKMDDTTKRSLENMLRAIIRQLFENSNCqsgalellyeqqnsqnsiTETQLLPVFREM 349
                 567889*******************99998888888877533344444447777777777777754433778888888766555544444444444555 PP

      AAA_22  83 eqalraravielliiDEaqhlrs.eealeeLrsllnlsrk 121
                 +  l++ +v +l  +DE q+ +   + lee+ ++++    
  EEA19856.1 350 ASTLDNFYV-VLDALDECQNRNDlFNFLEEIGTWQD---V 385
                 555555555.77777777776324555555555554...4 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.0     0.058        61      53     111 ..      25      88 ..      11      98 .. 0.73
   2 !   11.9   0.5   0.00016      0.17       5      63 ..     254     320 ..     251     406 .. 0.68

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.058
      AAA_14  53 lelileklke.ekktylflDEiqevpewekalkslvdeg.....knldvivtGSnskllskeiat 111
                 ++++++  k+ e++ +++  Ei  ++ + ++lk+++d+g     +nl++  +GS+s   s ++++
  EEA19856.1  25 MQYVKSA-KNvEGELLILVREIGGLKIVLDTLKHVLDRGkelhdRNLQLQGSGSSSASTSANTNN 88 
                 4555554.334789999999*****************6533444678888888888887776665 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 0.00016
      AAA_14   5 lvitGaRrvGKTtllkqlikell.....vkkesilyinldderdkkladpekllelilek.lke...e 63 
                 l + G   +GKT l  +++++l       +++  +y+ ++ ++++k++ + ++l++i ++ +++   +
  EEA19856.1 254 LWLYGTVGCGKTILSSNVAEDLSthsasEPNKALVYFYFKMDDTTKRSLE-NMLRAIIRQlFENsncQ 320
                 67889999**********99988999997777777777777666555544.34444444423333342 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   1.2e-05     0.013       1      36 [.     254     290 ..     254     335 .. 0.81
   2 ?    3.1   0.0      0.11   1.2e+02      26      60 ..    1109    1142 ..    1085    1152 .. 0.71

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 1.2e-05
  RNA_helicase   1 iwlyGpsgeGKStlakeLakallkkl.klkkkdsvys 36 
                   +wlyG  g+GK+ l+ ++a++l++++  +++k  vy+
    EEA19856.1 254 LWLYGTVGCGKTILSSNVAEDLSTHSaSEPNKALVYF 290
                   6**********************99866777777776 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.11
  RNA_helicase   26 lklkkkdsvysrnpeddfwdgYtgqevvvidDfgq 60  
                    l + + +++y+  +++++w g ++++ + + Df +
    EEA19856.1 1109 LCEVHIEQYYT-RTSQSMWRGVRRPANTSFTDFDA 1142
                    34444455555.78999***************987 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0   9.7e-07     0.001      21     148 ..     248     367 ..     239     392 .. 0.74
   2 ?   -0.5   0.1       1.4   1.4e+03     106     161 ..     456     534 ..     404     538 .. 0.69

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 9.7e-07
      AAA_16  21 sgrpelvllsGesGvGKsslvrellralekd......ggif.lrgkcdqlesaipysalaqalareellrqlldeaesaeleawrekleealaavpela 112
                 s+ ++l+ l+G  G+GK+ l   +++ l+++      ++++ ++ k d+  +++++   ++a+ r +l++  + ++ + el + ++  + +++      
  EEA19856.1 248 SSPGSLLWLYGTVGCGKTILSSNVAEDLSTHsasepnKALVyFYFKMDDT-TKRSLENMLRAIIR-QLFENSNCQSGALELLYEQQNSQNSIT------ 338
                 443499********************999999999985555588888888.33333345555545.666666666777777777777776666...... PP

      AAA_16 113 gaeasrllellkrllallsrderplvlvlDdlqwad 148
                    +++ll +++++++ l +    +++vlD l+  +
  EEA19856.1 339 ---ETQLLPVFREMASTLDN----FYVVLDALDECQ 367
                 ...68888888888866655....******999654 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 1.4
      AAA_16 106 a.....................avpelagaea...srllellkrllallsrderplvlvlDdlqwadeaslql.laaLlrl 161
                 +                       p+l+ a+    + l+++ +++l+++++ e    + l  ++w+ ++   l +++L++l
  EEA19856.1 456 TtksdgmfqwvvcqlealvkciRPPQLRKALNslpETLYDTYAEMLDKIHE-EN-YEVALRMFHWLLFSNKPLsIEELAEL 534
                 344555555555555555566533444444445669999999999999998.77.99999999999999999999999875 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.8   0.0   2.9e-05      0.03       2      90 ..     255     349 ..     254     369 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 2.9e-05
      AAA_18   2 lltGtpGvGKttlakeLskrlgfgvnlrdvakenglllevdpealdeskrldedkldklldaleenss..........aleegknlvidghlaelesea 90 
                 +l Gt G+GKt l+ ++++ l  ++++ +   +   ++++  +  d +kr  e++l +++++l ens+           +++ +n + + +l   + e+
  EEA19856.1 255 WLYGTVGCGKTILSSNVAEDL--STHSASEPNKALVYFYFKMD--DTTKRSLENMLRAIIRQLFENSNcqsgalellyEQQNSQNSITETQLLPVFREM 349
                 589*****************9..99999999999999999999..99******************9998777777776666666666666666666554 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.1   4.8e-05     0.051      21     146 ..     252     402 ..     242     431 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 4.8e-05
                 EEEEEEESTTSSHHHHHHHHCCSHCCCCCCBTEEEEE....................EEESXXHHHHHHHXXHHHHHCCCTTSSSS-STTSHHHHHHHH CS
      NB-ARC  21 lvvalvGmgGvGKttlakqilnksdevegrFdsvawv....................vvsktdkseeiletilkeLslseddleekeeveslkrklvrl 99 
                  ++ l+G  G+GKt+l++++ +++++     +  a v                     + + ++ ++ +   l+ L+++++ +++ +e + l   ++r 
  EEA19856.1 252 SLLWLYGTVGCGKTILSSNVAEDLSTHSASEPNKALVyfyfkmddttkrslenmlraIIRQLFENSNCQSGALELLYEQQNSQNSITETQ-LLP-VFRE 348
                 56889******************8888877777777778999999999999999998889999999999999998888877777777776.444.4444 PP

                 CCCT..TEEEEEEEE-SHHH.......H.....HHHHCHTTSEEEEEESBC.CCCCC CS
      NB-ARC 100 Lltk..rfllvlDDVweeed.......wdkigvvlparenrlrvllTTRde.evana 146
                 + +   +f +vlD   e ++       +++ig     ++  ++ llT+Rde ++++ 
  EEA19856.1 349 MASTldNFYVVLDALDECQNrndlfnfLEEIG---TWQDVNIHLLLTSRDErDITET 402
                 44444788888875544444334633333333...3466888888999885256555 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   5.9e-05     0.063       2      35 ..     255     298 ..     254     403 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 5.9e-05
                 EEESSTTSSHHHHHHHHHHHHTHE..........EEEEETTTCS CS
         AAA   2 llyGppGtGKTllakavakelgve..........fleisgsell 35 
                  lyG+ G+GKT+l + va++l+++          ++ +++ + +
  EEA19856.1 255 WLYGTVGCGKTILSSNVAEDLSTHsasepnkalvYFYFKMDDTT 298
                 59******************975544455555554444444444 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   9.3e-05     0.098       6      59 ..     229     291 ..     224     299 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 9.3e-05
                 HHHHHHHHHHHCH.........TEEEEEEESTTSSHHHHHHHHHHHTT------TTTTSEEEE CS
        TsaE   6 etealgkklakal.........gdvilLeGdLGaGKTtlvrglakalgveevkSPTFtlveeY 59 
                  t++ g+ l +           g+++ L+G +G+GKT l+ ++a+ l  ++ + P  +lv  Y
  EEA19856.1 229 RTKNTGSWLLQREqytdwksspGSLLWLYGTVGCGKTILSSNVAEDLSTHSASEPNKALVYFY 291
                 5666666665533444444444567*********************98877777766666666 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   0.00013      0.14      17      71 ..     248     312 ..     244     375 .. 0.71

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00013
    ATPase_2  17 repneiyfiYGpegsGKtaLlkeiienledkdk......yviyyialreesiskldefie....e 71 
                 ++p + + +YG  g+GKt L  +++e l+ ++        v +y+++ +    +l+++++    +
  EEA19856.1 248 SSPGSLLWLYGTVGCGKTILSSNVAEDLSTHSAsepnkaLVYFYFKMDDTTKRSLENMLRaiirQ 312
                 56788899********************8777677888889999999988888888875544441 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00026      0.28      32     154 ..     250     366 ..     235     374 .. 0.61

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00026
      AAA_25  32 agelallaGapgtGKttlaldlalavatGkpwlgpvapeqgkVlyvsaEdsedelrrRlravgeal.........rddarllvldlagveslpLfakdr 121
                  g+l  l+G  g+GKt l +++a +++t +   +p  ++     y   +d   +++r l+ +++a+          + +            l L+++++
  EEA19856.1 250 PGSLLWLYGTVGCGKTILSSNVAEDLSTHS-ASEP--NKALVYFYFKMDD---TTKRSLENMLRAIirqlfensnCQSGA-----------LELLYEQQ 331
                 589999*********************955.3332..2444444445555...555555555555532225544423333...........44444433 PP

      AAA_25 122 ggtl..ltadvdaleaaieevegvrlvviDplsra 154
                 +++   ++ ++  + +++ ++ +   vv+D l+++
  EEA19856.1 332 NSQNsiTETQLLPVFREMASTLDNFYVVLDALDEC 366
                 33333234445555555555555557999988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1166 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       662  (0.0369234); expected 358.6 (0.02)
Passed bias filter:                      552  (0.0307881); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              17  [number of targets reported over threshold]
# CPU time: 0.87u 0.30s 00:00:01.17 Elapsed: 00:00:00.47
# Mc/sec: 7435.50
//
Query:       EEA19857.1  [L=131]
Description: hypothetical protein PMAA_006250 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.4e-33  113.5   0.1    8.1e-33  113.4   0.1    1.0  1  Profilin  Profilin


Domain annotation for each model (and alignments):
>> Profilin  Profilin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.4   0.1   4.5e-37   8.1e-33       1     125 [.       1     129 [.       1     131 [] 0.96

  Alignments for each domain:
  == domain 1  score: 113.4 bits;  conditional E-value: 4.5e-37
                 HHHHHHHHCCCHHCSSESEEEEEETTSSSEEEEETTGG--HHHHHHHHHHHHSTCHHHHH-EEETTEEEEEEEEET..TE..EEEEETTEEEEEEE-SS CS
    Profilin   1 msWqayvdesllgtgkvdkAaIigadggsvwaasegfkvtpeevkaivkafkdpsklqsnGvtiggekYlviradd..es..iygkkgkegvvivktkq 95 
                 msW++y++++++g+g+vdkA Ii+++g+++w +s++ +++pee+++i+ af+d+s++ ++G+t++g+kY++ + d+  ++  +++ kgkeg++++k+ q
  EEA19857.1   1 MSWDGYLSQHIVGSGHVDKAIIIDQTGQAIWGKSSETQLSPEEMNKIAFAFNDSSNAEKEGITVEGRKYFFSKIDEldNIpvLHCAKGKEGIIAAKCSQ 99 
                 9**************************************************************************65455769999************* PP

                 EEEEEEE-TTS-HHHHHHHHHHHHHHHHHC CS
    Profilin  96 alviavydegvqpgnankavekladyLisa 125
                  +++ +y+e+   g+a + ++  a++Li +
  EEA19857.1 100 SILVSHYPESSPVGTAIDFIQGQAKHLIAN 129
                 ***************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (131 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       495  (0.0276089); expected 358.6 (0.02)
Passed bias filter:                      465  (0.0259356); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.29s 00:00:00.71 Elapsed: 00:00:00.45
# Mc/sec: 879.30
//
Query:       EEA19858.1  [L=457]
Description: hypothetical protein PMAA_006260 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      9e-50  169.9   0.1    1.3e-49  169.4   0.1    1.2  1  DDE_Tnp_1_7  Transposase IS4


Domain annotation for each model (and alignments):
>> DDE_Tnp_1_7  Transposase IS4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  169.4   0.1   7.2e-54   1.3e-49       2     310 ..      69     426 ..      68     447 .. 0.89

  Alignments for each domain:
  == domain 1  score: 169.4 bits;  conditional E-value: 7.2e-54
  DDE_Tnp_1_7   2 pvelFelflpdkilerivkatNayakqk.........kkwleltaeElkaFlGllllmglvrlpsvedyWstkdfyg....npllseiMsreRFeeil 86 
                  p+++F+lf+++++++ +++ tN+ya  k         ++w+ +t  ElkaF+G+++ mg  + p+++dyW+++++ +    n++ls +++  RFe++ 
   EEA19858.1  69 PYQIFSLFFTEDLFKVLADNTNMYAYAKlsknmnphhRNWRSTTPGELKAFVGAQIYMGFTKEPQLKDYWDEEKHNKsvhaNHPLSNYITCFRFEQLK 166
                  9**********************************************************************9995555678***************** PP

  DDE_Tnp_1_7  87 salhladn........................stkkaekdklkkvrelidslnermqkvyrpsqtlvldeslvlfkgrvpfkqylpgkprkvgiklhv 160
                  + +h++++                        s+++ +    +kv  ++d l +  +++y ps+++++de +v  +gr +    +p+kp   g+k++v
   EEA19858.1 167 RFFHISEPsevpggfistyyrpepteeeelqlSEEQLSGIWWHKVHTVFDILRKASKNLYIPSSNISIDEAMVCSHGRSSHTYKMPNKPISQGFKIFV 264
                  ***********************9999888664444488999******************************************************** PP

  DDE_Tnp_1_7 161 lcdsqtgyilalelyegearnlrl..srelgktnalvlrLleplqgkg..rvvvmdnfftslellqeLakkgtyavGtlkknrsglPkeltqklpkge 254
                  l+d   gy + +++  ++++ ++    +el+kt ++v +L+++l + +  + +++dn+fts++l+++L++ ++ a Gt +  ++++P+ l++ ++ g+
   EEA19858.1 265 LAD--HGYCYYFYPASRTKGVVEVgmAKELTKTGQMVYELVQTLPKDNktYDLYLDNYFTSVNLFKALREIQVGARGTTRP-HKEFPNLLKKLKDLGS 359
                  ***..9**********999877653378****************965555*******************************.77***88876666666 PP

  DDE_Tnp_1_7 255 llaryg......gplmllkwndrkkvkllstyss....qklveskersgqki.karpklvedYnqal 310
                     +++      +++  ++w d++ v+ l+t+++    ++ +e+ +r+ qk+    p +++++ ++ 
   EEA19858.1 360 YIPYHKvcaipvNDVLCVAWQDNNIVLALTTIHTvdqtDDYIERTRRRPQKTsTNGPLVHKEFGEQA 426
                  666666666666**********************887666699999999998667888888877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (457 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       447  (0.0249317); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.44
# Mc/sec: 3109.45
//
Query:       EEA19859.1  [L=652]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (652 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       531  (0.0296168); expected 358.6 (0.02)
Passed bias filter:                      297  (0.0165653); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.61u 0.29s 00:00:00.89 Elapsed: 00:00:00.49
# Mc/sec: 4012.60
//
Query:       EEA19860.1  [L=2022]
Description: DEAD/DEAH box helicase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
     2e-130  433.5   0.2    4.4e-80  268.6   0.1    2.3  2  Sec63         Sec63 Brl domain
    1.2e-51  174.9   0.4    2.4e-26   92.5   0.6    3.2  3  DEAD          DEAD/DEAH box helicase
    6.2e-22   78.4   0.0    8.7e-11   42.1   0.0    2.7  2  ResIII        Type III restriction enzyme, res subunit
    2.3e-16   60.1   0.0    1.6e-06   28.4   0.0    4.5  4  Helicase_C    Helicase conserved C-terminal domain
    1.5e-08   35.0   0.3    0.00034   20.9   0.0    3.6  2  AAA_22        AAA domain
    7.9e-08   32.2   0.2     0.0042   16.8   0.2    2.5  2  AAA_30        AAA domain
    4.5e-07   30.3   0.8     0.0041   17.4   0.7    2.9  2  AAA_19        AAA domain
     0.0024   18.0   0.0     0.0082   16.3   0.0    1.9  1  Helicase_PWI  N-terminal helicase PWI domain
  ------ inclusion threshold ------
       0.02   14.6   0.1        5.5    6.7   0.0    3.4  3  IstB_IS21     IstB-like ATP binding protein
      0.083   12.3   0.3         17    4.7   0.0    3.5  4  TniB          Bacterial TniB protein
       0.11   12.0   0.0         13    5.3   0.0    2.5  2  AAA_7         P-loop containing dynein motor region
          2    8.8   4.2        7.8    6.8   0.0    3.7  4  AAA_16        AAA ATPase domain


Domain annotation for each model (and alignments):
>> Sec63  Sec63 Brl domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  268.6   0.1   2.9e-83   4.4e-80       2     256 ..     792    1096 ..     791    1097 .. 0.98
   2 !  162.8   0.0   5.6e-51   8.4e-48       1     253 [.    1633    1991 ..    1633    1993 .. 0.91

  Alignments for each domain:
  == domain 1  score: 268.6 bits;  conditional E-value: 2.9e-83
                  CHHHHHHHHHT--HHHHHHHHHHS-TT--HHHHHHHHHTSGGGGGS---TTHHHHHHHHH.HTSSS--SSSTTSHHHHHHHHHHHHHTT---SSHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       Sec63    2 telGriaShYyisyetiklfneslkpnttlkdlLeilssasEFeeipvReeEkkelkkLl.ekvpikvkediespeaKvniLlqayisrlklegsdl 97  
                  +++GriaS++y+  ++i++fne+++p+ +++d+L+++s++ EF++i+ Re+E kel++L  e ++ +v++d +s++aK+niLlq+yisr kle+++l
  EEA19860.1  792 KDVGRIASQFYVLQTSIEIFNEMMRPRASEADVLKMISMSGEFDNIQARENESKELDRLReEALQTEVEGDNDSSHAKTNILLQSYISRAKLEDFAL 888 
                  689*********************************************************6679********************************* PP

                  HHHHHHHHHHHHHHHHHHHHHHHHTTBHHHHHHHHHHHHHHHHTS-TT................................................. CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................................................. RF
       Sec63   98 vsDlkyilqnairilralveillskgwlslalslleLskmveqrlwds................................................. 145 
                  vsDl+y++q+  ri+ral+ i+l+++w   ++ ll+++k++e+++w++                                                 
  EEA19860.1  889 VSDLAYVAQQSARICRALFMIALNRRWGYQCQVLLSMCKSIEKQIWPFqhpfhqfdlpmpimknldeklptssiesmrdmepaeighlvhnhrmgnt 985 
                  **********************************************999************************************************ PP

                  .......S--EEEEEEECEBTTSEEEEEEEEEESSSS-SCTSSS-CH..TSBEEEEEEEEETTTTEEEEEEEEEESSTTTTTEEEEEEEEEEE-.SS CS
                  .......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       Sec63  146 .......lPkleieaevqpitrsklrvevtiereeeeskpdfpwdkk..gksekfwlvvedsendellaikrvtlekkklastqevkleftvplsep 233 
                         +P+l++eae+ p+ r++lr+++++        p+f+w+++  g se+ w++ve+s+++e++++++++l++kkl +   ++l+ft+pls+p
  EEA19860.1  986 lsklldnFPTLTVEAEIAPLNRDVLRIRLSLY-------PEFTWNDRhhGASEGYWIWVENSDTSEIYHHEYFILSRKKLYD--DHELNFTIPLSDP 1073
                  ********************************.......************************************9998775..999********** PP

                  CCEEEEEEEEESSSSS-EEEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxx RF
       Sec63  234 gpkqltvrlisdswlgldqevti 256 
                  +p q++vr++sd+wlg+++  ++
  EEA19860.1 1074 LPAQIYVRAMSDRWLGAETVTPV 1096
                  ******************99887 PP

  == domain 2  score: 162.8 bits;  conditional E-value: 5.6e-51
                  ECHHHHHHHHHT--HHHHHHHHHHS-TT--HHHHHHHHHTSGGGGGS---TTHHHHHHHHHHTSSS--......SSSTTSHHHHHHHHHHHHHTT-- CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxx RF
       Sec63    1 ptelGriaShYyisyetiklfneslkpnttlkdlLeilssasEFeeipvReeEkkelkkLlekvpikv......kediespeaKvniLlqayisrlk 91  
                  +t  G+i+S+Yy+s++ti+ ++++  ++ + +++L  ++sa+EF+e+pvR++E+  +++L++++pi+       +  + +p+ K+++Llqay+sr++
  EEA19860.1 1633 STPFGKIMSYYYLSHKTIRYLMSHAIRQPSFEQVLAWMCSATEFDELPVRHNEDLVNAELAKNLPISSlpegmgDLPMWDPHIKAFLLLQAYMSRID 1729
                  5889**************************************************************9999887668899****************** PP

                  -SSHHHHHHHHHHHHHHHHHHHHHHHHHHHTTBHHHHHHHHHHHHHHHHTS-TT........................................... CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........................................... RF
       Sec63   92 legsdlvsDlkyilqnairilralveillskgwlslalslleLskmveqrlwds........................................... 145 
                  l+ sd+v D++++l+++iri++a +++l++ g+l ++  +++L +++++++w+                                            
  EEA19860.1 1730 LPISDYVGDQTSVLDQGIRIIQASIDVLAELGYLPACRMMMTLLQCIKSARWPEdhplsilpgiepeiltaavasnetkknkrastnspdslvalss 1826
                  ****************************************************888****************************************** PP

                  ...................................S--EEEEEEECEBTTSEEEEEEEEEESSS..S-S.....CTSSS-CHTSBEEEEEEEEETT. CS
                  ...................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxx.....xxxxxxxxxxxxxxxxxxxxxx. RF
       Sec63  146 ...................................lPkleieaevqpitrsklrvevtiereee..esk.....pdfpwdkkgksekfwlvvedse. 199 
                                                     lP+l+i  +v+    s+ ++++++ r++   +s+     p+fp+ +   +e+ +l+v  s+ 
  EEA19860.1 1827 mrpativqalnetlsstptfrplathqvdkivtsaLPRLSI--SVS--DISPKSITISLARQNTplTSDfkihaPRFPKPQ---TEGYFLIVTASSg 1916
                  ****************************************9..333..33445566667755556633346678*******...9999999996552 PP

                  ..TTEEEEEEEEEESSTTTTTEEEEE....................EEEEEE-.SSCCEEEEEEEEESSSSS-EEE CS
                  ..xxxxxxxxxxxxxxxxxxxxxxxx....................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       Sec63  200 ..ndellaikrvtlekkklastqevk....................leftvplsepgpkqltvrlisdswlgldqe 253 
                    n ella+krv+  + + ++++e++                    + ++ p+ +    ++ v ++sds++g++ +
  EEA19860.1 1917 egNGELLALKRVSWFNPQARNNTEHSrgqrrnngitakatvkfpneFLLSSPT-DAATRKVDVLIVSDSYIGMEWK 1991
                  2267*******9999988888888889*****************998888866.6669***************986 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.5   0.6   1.6e-29   2.4e-26       5     172 ..     283     465 ..     279     469 .. 0.85
   2 ?   -3.1   0.0       3.8   5.7e+03     154     169 ..     612     625 ..     600     628 .. 0.69
   3 !   78.4   0.0   3.6e-25   5.4e-22       2     168 ..    1142    1305 ..    1141    1312 .. 0.86

  Alignments for each domain:
  == domain 1  score: 92.5 bits;  conditional E-value: 1.6e-29
                 HHHHHHHH.TTCEEEEEESTTSSHHHHHHHHHHHHHHHS...............TTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSH CS
                 xxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   5 aeaiplil.gggdvlvaaeTGsGKTlaflipvlqivyet...............kgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaa 87 
                 +  ++ ++ + +++l++a+TG+GKT a+++ +l++++++                + +  k+++v+P+++La ++ ++l k++  ++++v  ++g + +
  EEA19860.1 283 SLLYDVAYkTSENMLICAPTGAGKTDAAMLTILNAIAKNvtpnpleepdatefvVQLDDFKIVYVAPMKALAAEVTEKLGKRLAWLGIKVRELTG-DMQ 380
                 555555553558************************99899998888888877767777**************************9999986655.555 PP

                 HHHHHHHHTTCSEEEEEHHHHHHHH..HCTSSH.CTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  88 rdqlskldngvdivvgtpgrlddll..stgkln.lsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlpkd 172
                   +++    +++i+v+tp+++d ++  stg  + +++vr+l++DE+++l d+ ++  i++++++++++ +++++  +++ lSATlp+ 
  EEA19860.1 381 LTKREI--VETQIIVTTPEKWDVVTrkSTGDTElVQKVRLLIIDEVHMLHDE-RGAVIESLVARTERQVESTQSLIRIVGLSATLPNY 465
                 444444..589***********9888877777779****************9.************999999997789********954 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 3.8
                 TTSTTTSEEEEEESSB CS
                 xxxxxxxxxxxxxxxx RF
        DEAD 154 cdgklqrqvivlSATl 169
                 ++g+   +v++++ATl
  EEA19860.1 612 AEGH--IKVLCCTATL 625
                 4444..55*******9 PP

  == domain 3  score: 78.4 bits;  conditional E-value: 3.6e-25
                  HHHHHHHHHHH.TTCEEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTT.STSEEEEEETTSSHHHHHHHHHT CS
                  xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD    2 diQaeaiplil.gggdvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkky.idlrvlliiggvaardqlskldn 96  
                  ++Q + +++++ +  +vl+  +TGsGKT a  +++  ++   ++++g k+++++P+++L+++ +++++k++ + ++l+++ ++g +++  + +++ +
  EEA19860.1 1142 PMQTQLFHTLYhTSANVLLGSPTGSGKTVACELAMWWAF---RERPGSKVVYIAPMKALVRERVQDWRKRITTaMGLKLVELTG-DNT-PDTRTI-R 1232
                  789999999994556*********************888...68***************************9878888875555.555.466777.7 PP

                  TCSEEEEEHHHHHHHH....HCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESS CS
                  xxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   97 gvdivvgtpgrlddll....stgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSAT 168 
                  ++di+++tp+++d +     ++g+  ++qv+++++DE++ l  + +++ ++ i+++++ i ++ k + +++ +S  
  EEA19860.1 1233 DADIIITTPEKWDGISrswqTRGY--VRQVSLVIIDEIHLLGGD-RGPILEIIVSRMNYIASQSKGSVRLMGMSTA 1305
                  9*************9977543444..*****************8.********************88887777754 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.3   0.0     3e-11   4.5e-08      21     170 ..     283     463 ..     258     464 .. 0.79
   2 !   42.1   0.0   5.8e-14   8.7e-11      22     147 ..    1153    1274 ..    1120    1305 .. 0.81

  Alignments for each domain:
  == domain 1  score: 33.3 bits;  conditional E-value: 3e-11
                 .........TTSEEEEEESTTSTHHHHHHHHHHHH-S.......................-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B CS
      ResIII  21 s.......krdkrglikmaTGtGKTlvaaklierllkkgkee..................kflflvprkslleqtleefkkflseaykeigkkvsgdkk 94 
                 s       k  +++li ++TG+GKT  a+ +i +   k+                     k++ ++p k+l     e++ k l      +  +++gd +
  EEA19860.1 283 SllydvayKTSENMLICAPTGAGKTDAAMLTILNAIAKNVTPnpleepdatefvvqlddfKIVYVAPMKALAAEVTEKLGKRLAWLG-IKVRELTGDMQ 380
                 14444555788999***********999888888887766557999******99999999999999999999999998877776543.36677888888 PP

                 --.......-SEEEEEHHHHHHTH........HHHTTT-SEEEEETGGGTTS......T.....TTHHHHHT---SEEEEEESS-S CS
      ResIII  95 kakekdstnkkilvttiqsldadseeeeeeseellrdrfdviiiDEaHrlgak.....k.....swreilekfkeavllglTATpe 170
                    ++++ +++i+vtt ++ d     ++++ ++ l ++  ++iiDE+H l+++     +     + r++    +   ++gl+AT++
  EEA19860.1 381 LT-KREIVETQIIVTTPEKWDVVT--RKSTGDTELVQKVRLLIIDEVHMLHDErgaviEslvarTERQVESTQSLIRIVGLSATLP 463
                 88.9999**************999..44556666777788************86555415555466667666667999******86 PP

  == domain 2  score: 42.1 bits;  conditional E-value: 5.8e-14
                  .TTSEEEEEESTTSTHHHHHHHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--.......-SEEEEEHHHHHHTH CS
      ResIII   22 krdkrglikmaTGtGKTlvaaklierllkkgkeekflflvprkslleqtleefkkflseaykeigkkvsgdkkkakekdstnkkilvttiqsldads 118 
                  +   ++l+  +TG+GKT+ +  +++  +++++ +k++ ++p k+l+    ++++k + +a   +  +++gd+     + + +++i++tt ++ d +s
  EEA19860.1 1153 HTSANVLLGSPTGSGKTVACELAMWWAFRERPGSKVVYIAPMKALVRERVQDWRKRITTAMGLKLVELTGDNTPD-TRTIRDADIIITTPEKWDGIS 1248
                  6678999*************88888888889999***********************999765777799999998.9999***************** PP

                  ........HHHTTT-SEEEEETGGGTTS. CS
      ResIII  119 eeeeeeseellrdrfdviiiDEaHrlgak 147 
                     ++++++    +  ++iiDE H lg++
  EEA19860.1 1249 ---RSWQTRGYVRQVSLVIIDEIHLLGGD 1274
                  ...8899999999999********99986 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0         2     3e+03      18      61 ..     343     390 ..     335     402 .. 0.71
   2 !   25.1   0.0   1.2e-08   1.8e-05      31     109 ..     578     668 ..     515     670 .. 0.65
   3 ?   -2.3   0.0       3.7   5.5e+03      13      38 ..     773     800 ..     764     825 .. 0.65
   4 !   28.4   0.0   1.1e-09   1.6e-06      33     109 ..    1419    1505 ..    1357    1507 .. 0.69

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 2
                 EEEEEESSHHHHHH.HHHHHHHT...TSTEEEESTTSTHHHHHHHHHH CS
  Helicase_C  18 kilifvntidrlek.vklllekk...gikvavlhgelpqnereeileq 61 
                 ki+ +++ +  + + ++ l ++    gikv  l+g+++  +re + +q
  EEA19860.1 343 KIVYVAPMKALAAEvTEKLGKRLawlGIKVRELTGDMQLTKREIVETQ 390
                 555555566633223555533336779**********99999977766 PP

  == domain 2  score: 25.1 bits;  conditional E-value: 1.2e-08
                 H..HHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEE....ESSSSSSH........HHHHHHHTTSSS CS
  Helicase_C  31 k..vklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVi....nfdlprnv........tsyiqriGRtgR 109
                    ++ l+  ++  + ++h+ l+ ++r+ + + f +g+++vL +t  ++ G+++p + +Vi     ++++            ++ q  GR+gR
  EEA19860.1 578 GarARELRDLFAAGFGAHHAGLTRSDRNLMERMFAEGHIKVLCCTATLAWGVNLPAAAVVIkgtqLYSAQ--EgkfvdlgiLDVLQIFGRAGR 668
                 13344445556888999********************************************555444444..033445555999*******99 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 3.7
                 TTTTSEEEEEESSHHHHHH..HHHHHHH CS
  Helicase_C  13 eeeggkilifvntidrlek..vklllek 38 
                   ++++++if +++++l    v  + ++
  EEA19860.1 773 VLQKSQMIIFNERTEELRAkdVGRIASQ 800
                 5678999999999996643334444333 PP

  == domain 4  score: 28.4 bits;  conditional E-value: 1.1e-09
                  HHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEE....ESSSS......SSHHHHHHHHTTSSS CS
  Helicase_C   33 klllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVi....nfdlp......rnvtsyiqriGRtgR 109 
                  + l+e  ++ +  +h+ l  ++r+ + e f ++++++L+at+ ++ G+++p   +V+     fd++       ++t++ q+ GR+gR
  EEA19860.1 1419 DALREALSFGIGLHHAGLVESDRQLAEELFANNKIQILVATSTLAWGVNLPAHLVVVkgtqYFDAKiegykdMDLTDVLQMLGRAGR 1505
                  3345555999999**************************************555555555555555767654557************ PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.9   0.7    0.0011       1.7       6     115 ..     294     441 ..     289     456 .. 0.56
   2 !   20.9   0.0   2.3e-07   0.00034      13     131 ..    1163    1303 ..    1153    1307 .. 0.82

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0011
      AAA_22   6 gilvvtGesGtGKTtllrrlleqldeeakaee.......................erpevvfvtlpsstsskdllrellralglelka........... 70 
                   +++++++G+GKT  +     ++ ++++ +                        +               k l+ e+ ++lg +l             
  EEA19860.1 294 ENMLICAPTGAGKTDAAMLTILNA-IAKNVTPnpleepdatefvvqlddfkivyvA-------------PMKALAAEVTEKLGKRLAWlgikvreltgd 378
                 568999999999997766655555.3333333678665544444444333333331.............344444444444444333355555555555 PP

      AAA_22  71 ................erlsseellealeqalrarav........ielliiDEaqhlr..seealeeLrsl 115
                                             ++ + ++++        ++lliiDE++ l   + +++e L+ +
  EEA19860.1 379 mqltkreivetqiivtT--------PEKWDVVTRKSTgdtelvqkVRLLIIDEVHMLHdeRGAVIESLVAR 441
                 44444434333333321........4444445555446667777779*********965447777777555 PP

  == domain 2  score: 20.9 bits;  conditional E-value: 2.3e-07
      AAA_22   13 esGtGKTtllrrlleqldeeakaeeerpevvfvtlpsst...sskdllrellralglelka....................erlsseellealeqal 86  
                  ++G+GKT+ ++  + ++    + e+++++vv++ + +       +d ++++  a+gl+l +                     + + + + +  +   
  EEA19860.1 1163 PTGSGKTVACELAMWWA----FRERPGSKVVYIAPMKALvreRVQDWRKRITTAMGLKLVEltgdntpdtrtirdadiiitTPEKWDGISRSWQTRG 1255
                  89********9998887....67778888885555554455499999**************999999999999888888865555555556666666 PP

      AAA_22   87 raravielliiDEaqhlr..seealeeLrsllnl..srkgvqliLvGtp 131 
                    r+v +l+iiDE++ l   +  +le ++s++n   s+++ ++ L+G+ 
  EEA19860.1 1256 YVRQV-SLVIIDEIHLLGgdRGPILEIIVSRMNYiaSQSKGSVRLMGMS 1303
                  66666.9**********7766***************9999999999985 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.2   2.8e-06    0.0042       2     104 ..     278     431 ..     277     457 .. 0.71
   2 !   12.7   0.0   5.1e-05     0.076       3     101 ..    1141    1272 ..    1140    1301 .. 0.70

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 2.8e-06
      AAA_30   2 lnaeQaaavealltsgdrvavltGpAGtGKt.talkalreaweaa.g..................grviglAptgkaAkvLaeelg.......ieasti 73 
                 ln  Q+ + + + ++++  +++ +p G+GKt  a+ ++ +a++++                    ++++ +Ap ++ A++++e+lg       i+ + +
  EEA19860.1 278 LNRMQSLLYDVAYKTSE-NMLICAPTGAGKTdAAMLTILNAIAKNvTpnpleepdatefvvqlddFKIVYVAPMKALAAEVTEKLGkrlawlgIKVREL 375
                 56667666666666554.79999********5234444555555524788********************************98884443322233322 PP

      AAA_30  74 akllkrlk............................grarlepg.tllivDEagmvdtkq 104
                    +  ++                            + ++l ++ +lli+DE+ m+  + 
  EEA19860.1 376 ---TGDMQltkreivetqiivttpekwdvvtrkstgD-TELVQKvRLLIIDEVHMLHDER 431
                 ...22222555778888899999999999999***64.5566666**********96544 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 5.1e-05
      AAA_30    3 naeQaaavealltsgdrvavltGpAGtGKttalkal.reaweaa.ggrviglAptgkaAkv.La............eelgieastiakllkrlk... 81  
                  n+ Q +++ +l ++++  ++l  p G+GKt a + +   a++++ g +v+ +Ap ++  ++ ++            +           l++ ++   
  EEA19860.1 1141 NPMQTQLFHTLYHTSA-NVLLGSPTGSGKTVACELAmWWAFRERpGSKVVYIAPMKALVRErVQdwrkrittamglK-----------LVELTGdnt 1225
                  6789999999988886.66777789*******99886566677779*********9999875773333333222220...........222222344 PP

      AAA_30   82 ...........................grarlepgtllivDEagmvd 101 
                                              r  +++ +l+i+DE+ +++
  EEA19860.1 1226 pdtrtirdadiiittpekwdgisrswqTRGYVRQVSLVIIDEIHLLG 1272
                  444455555566667788889999985333455559******98775 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.7   2.8e-06    0.0041       9     129 ..     292     442 ..     287     457 .. 0.68
   2 !    9.7   0.0   0.00066      0.98       7     112 ..    1152    1269 ..    1144    1289 .. 0.79

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 2.8e-06
      AAA_19   9 kekvllvtaGpGtGKTrvlkhivallvelggvkp................eeillvaftgrAakelrerlaalgae...............atTiHrla 76 
                 +++++l+ a+ G GKT   +  +  +++ +  +                  +i+ va+ +  a e++e+l   g++                 T  ++ 
  EEA19860.1 292 TSENMLICAPTGAGKTDAAMLTILNAIAKNVTPNpleepdatefvvqlddFKIVYVAPMKALAAEVTEKL---GKRlawlgikvreltgdmQLTKREI- 386
                 6789************87665555555544333358999*****************************99...4444456555554444442222222. PP

      AAA_19  77 lldfddlltealelle............eaeeekklqeee.llivDEfqdvdelqyrLlkallgek 129
                  +        + +++             ++ +++ + ++  lli+DE+ ++ +   ++++ l+ ++
  EEA19860.1 387 -V--------ETQIIVttpekwdvvtrkSTGDTELV-QKVrLLIIDEVHMLHDERGAVIESLVART 442
                 .2........22222234445556666444445555.5555***********99999988888655 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.00066
      AAA_19    7 alkekvllvtaGpGtGKTrvlkhivallvelggvkpeeillvaftgrAakelrerlaalgaeatTiHrlalldfddlltealelle........... 92  
                  ++++ ++l+  + G+GKT   + ++ ++ +++  +  +++ +a+ + A   +rer++   +++tT  +l l+++++++t     ++           
  EEA19860.1 1152 YHTSANVLLGSPTGSGKTVACELAMWWAFRER--PGSKVVYIAPMK-A--LVRERVQDWRKRITTAMGLKLVELTGDNTPDTRTIRdadiiittpek 1243
                  5677788889999****988777777777766..669******975.4..4688999999********99999998888888888888888889999 PP

      AAA_19   93 ......eaeeekklqeee.llivDEfq 112 
                        + +++  + ++  l+i+DE+ 
  EEA19860.1 1244 wdgisrSWQTRGYV-RQVsLVIIDEIH 1269
                  99998755566677.55559****986 PP

>> Helicase_PWI  N-terminal helicase PWI domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   5.5e-06    0.0082      11      77 ..      85     152 ..      81     163 .. 0.90

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 5.5e-06
  Helicase_PWI  11 dafWLqrelkkiykDae..eaqelaeevleiLkseadelrelEnkLvelldydkfdliklllknrekiv 77 
                   d  WL+ ++++  + ++  +++ l ++++ +L+s++ +  el+ +L e++++d +dl+  ++++r+ i+
    EEA19860.1  85 DHSWLESRCQQLAAQKSglDSEALLQQIVALLASDSGD-DELQMSLAEIIGFDDLDLVIDIITHRQDIL 152
                   677999999998886554589999***********766.9**************************997 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   0.0    0.0037       5.5      38      74 ..     284     320 ..     271     323 .. 0.75
   2 ?   -1.3   0.0       1.1   1.6e+03     106     121 ..     413     428 ..     404     446 .. 0.76
   3 ?    3.2   0.0     0.043        65      45      87 ..    1153    1198 ..    1137    1217 .. 0.73

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0037
   IstB_IS21  38 LatlsfiekkenivllGpsGvGKshlaialgveavra 74 
                 L  +   +++en++++ p+G+GK+  a+    +a+++
  EEA19860.1 284 LLYDVAYKTSENMLICAPTGAGKTDAAMLTILNAIAK 320
                 4444445789**************9887666666655 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.1
   IstB_IS21 106 llkvdllilDdlgllp 121
                 ++kv+lli+D++ +l+
  EEA19860.1 413 VQKVRLLIIDEVHMLH 428
                 6799*******97664 PP

  == domain 3  score: 3.2 bits;  conditional E-value: 0.043
   IstB_IS21   45 ekkenivllGpsGvGKshlaialgve.avr..aglsvlfvr.vedLv 87  
                  ++++n++l  p+G GK+ +a+ l++  a r   g +v+++  +++Lv
  EEA19860.1 1153 HTSANVLLGSPTGSGKT-VACELAMWwAFRerPGSKVVYIApMKALV 1198
                  4678999999******9.68888875244433688888875244554 PP

>> TniB  Bacterial TniB protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0     0.056        84      19      50 ..     277     308 ..     271     349 .. 0.86
   2 ?    4.7   0.0     0.012        17     119     132 ..     415     428 ..     394     440 .. 0.86
   3 ?   -3.3   0.0       3.3   4.9e+03      36      53 ..    1156    1173 ..    1145    1173 .. 0.84
   4 ?   -0.9   0.0      0.61   9.1e+02     119     131 ..    1259    1271 ..    1256    1307 .. 0.72

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.056
        TniB  19 ilerLeeLleypkrkrmpnlllvGdsnnGKtm 50 
                  l+r+++Ll     k  +n+l++ ++  GKt 
  EEA19860.1 277 SLNRMQSLLYDVAYKTSENMLICAPTGAGKTD 308
                 68899999999999999**************6 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.012
        TniB 119 kvrvLiiDEihnll 132
                 kvr+LiiDE+h l 
  EEA19860.1 415 KVRLLIIDEVHMLH 428
                 89*********875 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 3.3
        TniB   36 pnlllvGdsnnGKtmive 53  
                   n+ll +++  GKt+ +e
  EEA19860.1 1156 ANVLLGSPTGSGKTVACE 1173
                  6999**********9875 PP

  == domain 4  score: -0.9 bits;  conditional E-value: 0.61
        TniB  119 kvrvLiiDEihnl 131 
                  +v ++iiDEih l
  EEA19860.1 1259 QVSLVIIDEIHLL 1271
                  7899******965 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0     0.024        36      23      58 ..     283     319 ..     279     328 .. 0.77
   2 ?    5.3   0.0    0.0086        13      23      51 ..    1145    1173 ..    1142    1181 .. 0.89

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.024
       AAA_7  23 syllelllknkkpvllvGptGtGKtviikd.llkkld 58 
                 s l +   k + ++l++ ptG GKt  ++  +l+++ 
  EEA19860.1 283 SLLYDVAYKTSENMLICAPTGAGKTDAAMLtILNAIA 319
                 56778889999**************776664666665 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0086
       AAA_7   23 syllelllknkkpvllvGptGtGKtviik 51  
                  + l+++l + + +vll  ptG+GKtv ++
  EEA19860.1 1145 TQLFHTLYHTSANVLLGSPTGSGKTVACE 1173
                  5689999******************9875 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.1       3.6   5.4e+03      80     106 ..      91     117 ..       9     151 .. 0.62
   2 ?    6.8   0.0    0.0052       7.8       9     164 ..     278     444 ..     276     453 .. 0.68
   3 ?   -3.7   0.1       8.8   1.3e+04      91     140 ..     844     889 ..     831     901 .. 0.55
   4 ?    0.7   0.0       0.4   5.9e+02      24      45 ..    1155    1176 ..    1144    1273 .. 0.78

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 3.6
      AAA_16  80 ellrqlldeaesaeleawrekleeala 106
                 + ++ql+++++  + ea  +++ + la
  EEA19860.1  91 SRCQQLAAQKSGLDSEALLQQIVALLA 117
                 334444444333333333333333333 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.0052
      AAA_16   9 leqLlsalervrsgrpelvllsGesGvGKsslv.rellralekdggiflrgkcdqlesaipysalaqalareellrqlldeaesaeleawrekleeala 106
                 l++++s+l +v+  ++e++l+  + G GK+  +  ++l+a+ k+    ++ +  + + a++   ++ +l   + ++ +  ++ +a++++  ekl ++la
  EEA19860.1 278 LNRMQSLLYDVAYKTSENMLICAPTGAGKTDAAmLTILNAIAKN----VTPNPLEEPDATE---FVVQL---DDFKIVYVAPMKALAAEVTEKLGKRLA 366
                 6788999999999999**************88878888899998....5555555544444...45555...334444444445677888888888888 PP

      AAA_16 107 ....avpelagaea...............srllellkrllallsrder.................plvlvlDdlqwadeaslqllaaLlrlles 164
                      v+el+g+                                  e+                   +l++D+++ + ++  +++++L++++e+
  EEA19860.1 367 wlgiKVRELTGDMQltkreivetqiivttP----------------EKwdvvtrkstgdtelvqkVRLLIIDEVHMLHDERGAVIESLVARTER 444
                 888888888888884444444444444442................333444444445555554269999999999999999999999988775 PP

  == domain 3  score: -3.7 bits;  conditional E-value: 8.8
      AAA_16  91 saeleawrekleealaavpelagaeasrllellkrllallsrderplvlv 140
                 s+el++ re+ +++  +v  + ++++   + ll++ +++++  e+ + lv
  EEA19860.1 844 SKELDRLREEALQT--EVEGDNDSSHAKTNILLQSYISRAKL-ED-FALV 889
                 33444444322221..22333333337777777777766665.55.5555 PP

  == domain 4  score: 0.7 bits;  conditional E-value: 0.4
      AAA_16   24 pelvllsGesGvGKsslvrell 45  
                  + +vll  + G+GK+   + ++
  EEA19860.1 1155 SANVLLGSPTGSGKTVACELAM 1176
                  36899999*******9876554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2022 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       653  (0.0364214); expected 358.6 (0.02)
Passed bias filter:                      542  (0.0302304); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 1.06u 0.31s 00:00:01.37 Elapsed: 00:00:00.47
# Mc/sec: 12833.13
//
Query:       EEA19861.1  [L=199]
Description: SNARE protein Ykt6, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.7e-14   52.7   0.6    5.5e-14   51.7   0.6    1.5  1  Synaptobrevin  Synaptobrevin
    4.7e-14   52.2   0.0    9.1e-14   51.3   0.0    1.5  1  Longin         Regulated-SNARE-like domain


Domain annotation for each model (and alignments):
>> Synaptobrevin  Synaptobrevin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.7   0.6   6.1e-18   5.5e-14       2      58 ..     137     193 ..     136     197 .. 0.96

  Alignments for each domain:
  == domain 1  score: 51.7 bits;  conditional E-value: 6.1e-18
                    XXHHHHHHHHHHCCCCHHCCHHHHCHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHH CS
  Synaptobrevin   2 ndklakikaevdevkdimkeNidkvlergekldeLvdktenLqssaqqFkkqarklk 58 
                    +d+++ki++e+d++k ++++ i++vlergek+d+Lv k++ L+++++ F +qa+k++
     EEA19861.1 137 ADSIMKIQQELDQTKIVLHKTIESVLERGEKIDSLVAKSDGLSAQSKMFYTQAKKQN 193
                    799***************************************************987 PP

>> Longin  Regulated-SNARE-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.3   0.0     1e-17   9.1e-14       2      75 ..      45     115 ..      44     123 .. 0.83

  Alignments for each domain:
  == domain 1  score: 51.3 bits;  conditional E-value: 1e-17
      Longin   2 klilkkishss.pqkltythdsytfhylaedgltylviadesyprrlaFafLeeikreFlakygtaktadaadlr 75 
                 k+++++    + +q++t++++sytfh +++dg++ ++++d++yp  +a ++L++i +eF++k+++ ++  +++l+
  EEA19861.1  45 KTVAERT---KpGQRQTIEEKSYTFHSMSRDGIAGVIVSDSEYPPLVAQQLLSKITDEFISKHPH-SEYANTNLP 115
                 6778885...2479**************************************************6.443444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (199 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       878  (0.0489709); expected 358.6 (0.02)
Passed bias filter:                      506  (0.0282224); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.29s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1336.16
//
Query:       EEA19862.1  [L=168]
Description: MGMT family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.6e-23   80.4   0.0    1.2e-22   79.8   0.0    1.3  1  DNA_binding_1  6-O-methylguanine DNA methyltransferase, DNA b
  ------ inclusion threshold ------
      0.026   14.4   0.0        4.1    7.4   0.0    2.3  2  DUF4224        Domain of unknown function (DUF4224)


Domain annotation for each model (and alignments):
>> DNA_binding_1  6-O-methylguanine DNA methyltransferase, DNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.8   0.0   1.4e-26   1.2e-22       4      81 .]      12     125 ..       9     125 .. 0.98

  Alignments for each domain:
  == domain 1  score: 79.8 bits;  conditional E-value: 1.4e-26
                    HHHHHHHTTS-TT-BEEHHHHHHHTT.TSCHHHHHHHHHTSS...................................BTTTSGGGGEEBTTSBCCT CS
  DNA_binding_1   4 qrVwellrqIpyGkvttYgeiAkllgkpkaaraVgqalaanp...................................lailvPcHRVvgadgklgg 64 
                    ++V+e++++Ip G+vttYg+iA+llg p++ar+Vg +l+++p                                   ++ +vP++RVv+++g++++
     EEA19862.1  12 NAVYEAVQEIPLGSVTTYGHIARLLGYPRRARQVGICLKHLPsnrtnrtsaadgagddesgqeedendeqgeiyhhfHDDNVPWQRVVNSRGTISH 107
                    68**************************************************************************99****************** PP

                    T.TTCHHHHHHHHHHTTS CS
  DNA_binding_1  65 y.agglerkralLeaEgv 81 
                    +  g+++r++ +L++Egv
     EEA19862.1 108 RgPGSASRQAIALRHEGV 125
                    *8899***********97 PP

>> DUF4224  Domain of unknown function (DUF4224)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.0    0.0035        31       7      20 ..      32      45 ..      31      47 .. 0.90
   2 ?    7.4   0.0   0.00046       4.1      16      36 ..     113     133 ..     112     135 .. 0.91

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.0035
     DUF4224  7 laeLTGykrrsaQa 20
                +a L Gy+rr++Q+
  EEA19862.1 32 IARLLGYPRRARQV 45
                6889*********6 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.00046
     DUF4224  16 rsaQakwLranGipfvvradG 36 
                  s+Qa +Lr +G+ + ++a G
  EEA19862.1 113 ASRQAIALRHEGVTVEQDAMG 133
                 59**************99977 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (168 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       512  (0.0285571); expected 358.6 (0.02)
Passed bias filter:                      425  (0.0237046); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.32s 00:00:00.79 Elapsed: 00:00:00.48
# Mc/sec: 1047.00
//
Query:       EEA19863.1  [L=360]
Description: cell cycle control protein (Cwf26), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.7e-49  166.8   5.3    3.7e-49  166.8   5.3    3.0  3  Bud13     Pre-mRNA-splicing factor of RES complex
  ------ inclusion threshold ------
        4.4    7.3  16.1       0.43   10.6   7.4    2.4  2  Nop16     Ribosome biogenesis protein Nop16


Domain annotation for each model (and alignments):
>> Bud13  Pre-mRNA-splicing factor of RES complex
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.1      0.47   4.3e+03      75      85 ..      23      33 ..       6      39 .. 0.55
   2 ?   -4.3  10.4         2   1.8e+04      18      68 ..     142     192 ..      64     202 .. 0.76
   3 !  166.8   5.3   4.2e-53   3.7e-49       1     144 [.     205     343 ..     205     344 .. 0.95

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.47
       Bud13 75 eelkekerwdD 85
                ++ ++k++++D
  EEA19863.1 23 KKKRKKNKHHD 33
                33334444444 PP

  == domain 2  score: -4.3 bits;  conditional E-value: 2
       Bud13  18 reaeaekkkkeeeekeekkkewgkGlvqkeekekrleelekekkkplarya 68 
                 +++e+e++++ee+  ++ +  ++ Gl +  ++ +  +++e+ kk +la  +
  EEA19863.1 142 QDMEEEEEEEEEDGGQRMESGARAGLQTAAQTAAMVAAQERRKKAELAAFQ 192
                 333444444444444555555666777777777777777777777776544 PP

  == domain 3  score: 166.8 bits;  conditional E-value: 4.2e-53
       Bud13   1 etvyRdktgrkidleekreaeaekkkkeeeekeekkkewgkGlvqkeekekrleelekekkkplaryaddedlneelkekerwdDPmaaflkkkkkkkk 99 
                 et+yRd++gr+i++++kr aea+k+++e+++ e+ +k++ +G+vq++ ke+r+e+l++++++plar+ +dedlneel++++rw+DP+a+fl++kk+  +
  EEA19863.1 205 ETIYRDASGRIINVAMKR-AEARKAAEEAAKAEQAAKDALMGDVQRQAKEERMEQLRSARAMPLARTIEDEDLNEELRQQDRWNDPAAQFLTTKKAGVS 302
                 7***************99.99***********************************************************************8884444 PP

       Bud13 100 kkskkkkpkykgpaappNRfgIkPGyrWDGvdRsnGfEkklfeal 144
                 k +   +p ykg  ++pNR+gI+PG+rWDGvdR+nGfEk++f+a+
  EEA19863.1 303 K-T--GRPLYKG-GFAPNRYGIRPGHRWDGVDRGNGFEKEWFQAR 343
                 4.3..49****9.9****************************986 PP

>> Nop16  Ribosome biogenesis protein Nop16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   1.5      0.03   2.7e+02      78     146 ..      23      95 ..       7     168 .. 0.46
   2 ?   10.6   7.4   4.8e-05      0.43      68     153 ..     178     263 ..     158     285 .. 0.50

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.03
       Nop16  78 kkkleeeesdekklskgearieRDeeGkivkviegk.kkkeneledpleeleedeekeeeee.....kkkktevv 146
                 kkk +++++++   s g + i+ D++   ++   g+ +++e + ++p     +++++++ ++     kk++ +vv
  EEA19863.1  23 KKKRKKNKHHDPLTSGGDGLIIADDDPPSLRAAAGDlNDNEYDENSPYIL--DSSASRALSAefkkkKKSSWKVV 95 
                 33334456667777788888888888888888888322222222222211..11111111112233322233333 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 4.8e-05
       Nop16  68 skanekeekekkklee....eesdekklskgearieRDeeGkivkviegkkkkeneledpleeleedeekeeeee..kkkktevvkeLekea 153
                 +++++ ++ + +        ++ ++++ + g   i RD++G+i++v +++ +++ +  ++  ++e+ +++    +  +++k+e  ++L + +
  EEA19863.1 178 AAQER-RK-KAE---LaafqASVKQQQQEGGGETIYRDASGRIINVAMKR-AEARKAAEEAAKAEQAAKDALMGDvqRQAKEERMEQLRSAR 263
                 22211.11.122...1334333444444445557**************93.33333333333322222222111133444555555555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (360 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1593  (0.0888505); expected 358.6 (0.02)
Passed bias filter:                      437  (0.0243739); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.69u 0.39s 00:00:01.08 Elapsed: 00:00:00.59
# Mc/sec: 1837.56
//
Query:       EEA19864.1  [L=585]
Description: serine protein kinase Sky1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.8e-40  137.9   0.0    4.5e-22   78.7   0.1    2.2  2  Pkinase         Protein kinase domain
    3.5e-14   52.7   0.2    1.1e-09   38.0   0.0    2.2  2  Pkinase_Tyr     Protein tyrosine kinase
  ------ inclusion threshold ------
      0.061   12.1   0.3      0.085   11.6   0.3    1.5  1  Pkinase_fungal  Fungal protein kinase


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.7   0.1   7.5e-26   4.5e-22       1     132 [.     112     254 ..     112     265 .. 0.86
   2 !   57.1   0.0   2.9e-19   1.8e-15     137     264 .]     392     552 ..     382     552 .. 0.83

  Alignments for each domain:
  == domain 1  score: 78.7 bits;  conditional E-value: 7.5e-26
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHS........CTTB--EEEEEEE....SSEEEEEEE--TTEBHHH CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklk........hpnivrlyevfee....kdelylvleyveggelad 87 
                 y++++klG G f++V   +++++gk+vA+K+++         ++++ Eik+l+k+          +++v l+++fe+      ++++v+e++ ++ l  
  EEA19864.1 112 YVVVRKLGWGHFSTVWLSRDTTNGKHVALKVVRSAAHYT---ETAIDEIKLLNKIVqanpshpgRKHVVSLLDSFEHkgpnGVHVCMVFEVLGEN-LLG 206
                 67899***************************9987776...568******9997545566333469*********9888889********9966.777 PP

                 HHH..HHSS--HHHHHHHHHHHHHHHHHHH.HTTEE-SS-SGGGEEEE CS
     Pkinase  88 lle..rkgslseeeakkiakqilegleylH.skgiiHrDlKpeNiLid 132
                 l++  +++ +++  +++i+kq+l gl+ylH + giiH DlKpeN+Li+
  EEA19864.1 207 LIKrwNHRGIPMPLVRQITKQVLLGLDYLHrECGIIHTDLKPENVLIE 254
                 777688889*********************6667*************8 PP

  == domain 2  score: 57.1 bits;  conditional E-value: 2.9e-19
                 EEE-SGTTSEESSSSCSBCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHHHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCT....SHH...HHHT CS
     Pkinase 137 lKitDFGlakelessskltsfvgtseYlAPEvlkeneyskkvDvWslGvilyelltgkppfsgekgkekvekeldqlekilkilg....etkeklpeas 231
                 +Ki+D+G a+ + ++  +t+ + t++Y++PEv+ + + ++++DvWs++++++el+tg  +f  ++g++ + k+ d++ +i+++lg        + ++ +
  EEA19864.1 392 VKIADLGNACWVGHH--FTNDIQTRQYRSPEVILGAKWGASTDVWSMACMVFELITGDYLFDPQSGTK-YGKDDDHIAQIIELLGnfprSLCISGRWSQ 487
                 9*********99985..799******************************************666665.888888889999999977652223333333 PP

                 TS................................-HHHHHHHHHHT-SSGCCSTTHHHHHTSGGG CS
     Pkinase 232 ei................................seeakdllkkllkkdpkkRltaeellqhpyl 264
                 ei                                  ++ ++l  +l+  p++R  a  + +h++l
  EEA19864.1 488 EIfnrrgelrnihrlrhwalpdvlrekyhftseeAIQISEFLLPMLELMPEDRANAGGMSNHEFL 552
                 348888999999*******************4444445578999**************9999986 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.0   0.0   1.8e-13   1.1e-09       4     144 ..     115     261 ..     112     285 .. 0.81
   2 !   12.6   0.0     1e-05     0.062     142     202 ..     392     446 ..     387     460 .. 0.78

  Alignments for each domain:
  == domain 1  score: 38.0 bits;  conditional E-value: 1.8e-13
                  EEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS.-....B...TTB--EEEEEESSSS....EEEEEE--TTEBHH CS
  Pkinase_Tyr   4 gkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkkl.k....h...pnivkllgvctkeep....llivteyvkgGdLl 89 
                   +klG G+f++V+  + +    ++  +Va+K++++ a+ +  e  ++e+k+++k+ +    h   +++v+ll    +++p    +++v+e + + +Ll
   EEA19864.1 115 VRKLGWGHFSTVWLSRDT----TNGKHVALKVVRSAAHYT--ETAIDEIKLLNKIvQanpsHpgrKHVVSLLDSFEHKGPngvhVCMVFEVLGE-NLL 205
                  689**********99887....88999******7776666..7888999999887543333333369*********888778779999998865.788 PP

                  HHHHHTCTTTSBHHHHHHHHHHHHHHHHHHHHTT.EEEST-SGGGEEEEETTEEEE CS
  Pkinase_Tyr  90 kfLrkkekekltlkdllsfalqvAkGmeyLeskk.lvHrdlaarNvLlsenkvvki 144
                    +++ +++ + +  + +++ qv  G++yL+++  ++H dl   NvL++ ++v +i
   EEA19864.1 206 GLIKRWNHRGIPMPLVRQITKQVLLGLDYLHRECgIIHTDLKPENVLIEIGDVEQI 261
                  8888888***********************987549************98666555 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 1e-05
                  EEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSEEEHHHHHHHHHHHHHHHHTTS CS
  Pkinase_Tyr 142 vkisDfGLardiekddeyvkkeeaklpvkWmapEslkekkftsksDvWsfGvllwEiftlg 202
                  vki+D G a  +      ++ ++     ++ +pE++   k   ++DvWs + +++E++t g
   EEA19864.1 392 VKIADLGNACWV-----GHHFTNDIQTRQYRSPEVILGAKWGASTDVWSMACMVFELIT-G 446
                  566666666655.....22333444556899**************************99.5 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.3   1.4e-05     0.085     312     342 ..     225     275 ..      10     411 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 1.4e-05
  Pkinase_fungal 312 lrDaIkghrsLflkagiLHrDiSenNilit....................d 342
                      ++++ g+  L++++gi+H D   +N+li                     d
      EEA19864.1 225 TKQVLLGLDYLHRECGIIHTDLKPENVLIEigdveqivktyvkeeqktekD 275
                     35688999*********************9888888888888865443331 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (585 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       645  (0.0359752); expected 358.6 (0.02)
Passed bias filter:                      460  (0.0256568); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.66u 0.33s 00:00:00.99 Elapsed: 00:00:00.50
# Mc/sec: 3546.42
//
Query:       EEA19865.1  [L=140]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (140 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       293  (0.0163422); expected 358.6 (0.02)
Passed bias filter:                      224  (0.0124937); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.41u 0.24s 00:00:00.64 Elapsed: 00:00:00.43
# Mc/sec: 984.06
//
Query:       EEA19866.1  [L=947]
Description: hypothetical protein PMAA_006340 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.9e-16   58.8   0.0      3e-09   37.3   0.0    2.4  2  Ank_2     Ankyrin repeats (3 copies)
    6.3e-12   44.6   0.0       0.03   14.9   0.0    4.9  4  Ank_3     Ankyrin repeat
      1e-10   41.6   0.3     0.0019   18.4   0.0    3.9  4  Ank_5     Ankyrin repeats (many copies)
      4e-10   40.0   0.0    5.2e-05   23.7   0.0    4.1  4  Ank_4     Ankyrin repeats (many copies)
    2.7e-08   33.9   0.2       0.26   11.8   0.0    3.9  3  Ank       Ankyrin repeat


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.3   0.0   8.4e-13     3e-09       9      81 ..     109     198 ..     101     200 .. 0.77
   2 !   19.0   0.0   4.3e-07    0.0015       9      81 ..     231     318 ..     218     320 .. 0.76

  Alignments for each domain:
  == domain 1  score: 37.3 bits;  conditional E-value: 8.4e-13
       Ank_2   9 nlelvklLl....egadpn....k..ngktaLhyAakngnleivklLle.h..ad......ndgrtpLhyAarsghleivklLlekgadinl 81 
                 n + v+ Ll    +   +n    +   g++++h+Aa  g ++i+kl+l+ h  ++       +  tpLh A+   h+ i+++Ll  ga++++
  EEA19866.1 109 NVHGVRRLLmedpS--QVNarlpDdsGGWSPIHLAACLGRTKIMKLILQtHlkVNpnmrsvVSQATPLHQAIIGRHPGIAEMLLRAGAQVDA 198
                 45778888865332..333436525799********************95477444355667799********99*********88*99986 PP

  == domain 2  score: 19.0 bits;  conditional E-value: 4.3e-07
       Ank_2   9 nlelvklLl.egadpn.k...ngktaLhyAakngnleivklLle....h........adndgrtpLhyAarsghleivklLlekgadinl 81 
                 +  +++ Ll +gad   +    g ++++ A  +  +ei+k++ e    +         dnd +t L++A+     e vk+Ll +g+d+ +
  EEA19866.1 231 DERIIEMLLrAGADYLhNsggRGYSIVFKASAH--VEILKIFFEtipaEdakhlaniRDNDRQTLLFHAVNRVDVEKVKYLLSRGVDPRV 318
                 345999***99988644247899*****99885..5*******95555155568555559999*******66679*******99*99876 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   8.2e-06      0.03       2      30 ..     134     163 ..     133     164 .. 0.93
   2 !   11.3   0.0   0.00012      0.43       3      30 ..     171     197 ..     169     198 .. 0.91
   3 ?    2.7   0.0     0.077   2.8e+02       4      29 ..     214     245 ..     212     247 .. 0.67
   4 !    9.6   0.0   0.00042       1.5       3      30 ..     291     317 ..     289     318 .. 0.93

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 8.2e-06
       Ank_3   2 GetpLhlAarsgnleivkfLle.nkgadvn 30 
                 G++p+hlAa  g+++i+k++l+ +  +++n
  EEA19866.1 134 GWSPIHLAACLGRTKIMKLILQtHLKVNPN 163
                 9*********************99999988 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00012
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvn 30 
                  tpLh+A+   ++ i+++Ll+  ga v+
  EEA19866.1 171 ATPLHQAIIGRHPGIAEMLLR-AGAQVD 197
                 6********************.899887 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.077
       Ank_3   4 tpLhlAarsgnl......e.ivkfLlenkgadv 29 
                 +pL lA++++        e i+++Ll+  gad 
  EEA19866.1 214 SPLELAVEQCVSqvtkddErIIEMLLR-AGADY 245
                 566666666666444443247******.89996 PP

  == domain 4  score: 9.6 bits;  conditional E-value: 0.00042
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvn 30 
                 +t+L++A+   ++e vk+Ll  +g+d++
  EEA19866.1 291 QTLLFHAVNRVDVEKVKYLLS-RGVDPR 317
                 8************99******.9***97 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.12   4.2e+02      31      56 .]     112     141 ..      96     141 .. 0.74
   2 ?    3.6   0.0     0.025        89      11      45 ..     130     165 ..     123     167 .. 0.72
   3 !   15.0   0.0   6.4e-06     0.023      17      40 ..     171     194 ..     153     200 .. 0.78
   4 !   18.4   0.0   5.4e-07    0.0019      10      53 ..     284     327 ..     278     329 .. 0.93

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.12
       Ank_5  31 vvrlLl...argadlnltdsrG.ltaldlA 56 
                  vr+Ll     +++++l d++G +++++lA
  EEA19866.1 112 GVRRLLmedPSQVNARLPDDSGgWSPIHLA 141
                 56666654444678889999999**99998 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.025
       Ank_5  11 rldgggntpLhvAakygaadvvrlLl..argadlnlt 45 
                 +  gg+ +p+h+Aa  g+  +++l+l     +++n++
  EEA19866.1 130 DDSGGW-SPIHLAACLGRTKIMKLILqtHLKVNPNMR 165
                 333444.999999999999999999977666666665 PP

  == domain 3  score: 15.0 bits;  conditional E-value: 6.4e-06
       Ank_5  17 ntpLhvAakygaadvvrlLlarga 40 
                  tpLh+A+ ++++ ++++Ll  ga
  EEA19866.1 171 ATPLHQAIIGRHPGIAEMLLRAGA 194
                 3*******************4444 PP

  == domain 4  score: 18.4 bits;  conditional E-value: 5.4e-07
       Ank_5  10 nrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltal 53 
                 n +d++++t L +A++++  + v++Ll rg+d+++++ +G+ta+
  EEA19866.1 284 NIRDNDRQTLLFHAVNRVDVEKVKYLLSRGVDPRVRCVSGQTAY 327
                 77888889***********************************8 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.8   0.0    0.0014         5      18      43 ..     114     142 ..     100     144 .. 0.80
   2 !   23.7   0.0   1.4e-08   5.2e-05       2      55 .]     135     190 ..     134     190 .. 0.94
   3 ?   -1.0   0.0       0.8   2.9e+03      10      43 ..     225     261 ..     212     270 .. 0.71
   4 !    9.2   0.0   0.00052       1.9       3      38 ..     292     326 ..     290     339 .. 0.87

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0014
       Ank_4  18 rlLl.ekgadinaq..dnrsGetalhiAa 43 
                 r+Ll e   ++na+  d++ G++++h Aa
  EEA19866.1 114 RRLLmEDPSQVNARlpDDSGGWSPIHLAA 142
                 5444487888****767777*******97 PP

  == domain 2  score: 23.7 bits;  conditional E-value: 1.4e-08
       Ank_4   2 ltaLhyaaisgrlelvrlLlek..gadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++++h aa  gr+++ +l+l++  ++++n+++  s+ t+lh A+ + ++ i+++Ll
  EEA19866.1 135 WSPIHLAACLGRTKIMKLILQThlKVNPNMRSVVSQATPLHQAIIGRHPGIAEMLL 190
                 689*****************96579******99*********************98 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 0.8
       Ank_4  10 i...sgrlelvrlLlekgadinaqdnrsGetalhiAa 43 
                 +   + ++++++ Ll  gad  + + ++G + + +A 
  EEA19866.1 225 SqvtKDDERIIEMLLRAGADYLHNSGGRGYSIVFKAS 261
                 1555788999999998899988876677777777774 PP

  == domain 4  score: 9.2 bits;  conditional E-value: 0.00052
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGeta 38 
                 t+L++a++  ++e v++Ll++g+d+  +   sG+ta
  EEA19866.1 292 TLLFHAVNRVDVEKVKYLLSRGVDPRVR-CVSGQTA 326
                 78999999999999**********9999.8889986 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   0.0   7.1e-05      0.26       2      30 ..     134     165 ..     133     167 .. 0.84
   2 !   11.4   0.0    0.0001      0.36       4      30 ..     172     199 ..     171     200 .. 0.86
   3 !    6.1   0.0    0.0048        17       4      26 ..     214     244 ..     212     249 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 7.1e-05
                 SBBHHHHHHHHTTHHHHHHHH..T.TTSTTCB CS
         Ank   2 GnTPLHlAatngkkriiklLL..h.GAnlnal 30 
                 G++P HlAa+ g + i kl+L  h   n+n++
  EEA19866.1 134 GWSPIHLAACLGRTKIMKLILqtHlKVNPNMR 165
                 99*******899999***99975556999986 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.0001
                 BHHHHHH...HHTTHHHHHHHH.TTTSTTCB CS
         Ank   4 TPLHlAa...tngkkriiklLL.hGAnlnal 30 
                 TPLH A+   ++g   i+++LL  GA ++a+
  EEA19866.1 172 TPLHQAIigrHPG---IAEMLLrAGAQVDAR 199
                 9*****9666666...******889*99986 PP

  == domain 3  score: 6.1 bits;  conditional E-value: 0.0048
                 BHHHHHH.......HHTTHHHHHHHH.TTTS CS
         Ank   4 TPLHlAa.......tngkkriiklLL.hGAn 26 
                 +PL lA+       t +++rii++LL  GA+
  EEA19866.1 214 SPLELAVeqcvsqvTKDDERIIEMLLrAGAD 244
                 577788666677778899********77998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (947 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       482  (0.0268838); expected 358.6 (0.02)
Passed bias filter:                      416  (0.0232026); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.74u 0.34s 00:00:01.08 Elapsed: 00:00:00.53
# Mc/sec: 5417.57
//
Query:       EEA19867.1  [L=359]
Description: hypothetical protein PMAA_006350 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.9e-22   77.6   0.0    3.9e-21   75.6   0.0    1.8  1  Pkinase          Protein kinase domain
    1.8e-17   63.5   0.0    1.3e-15   57.4   0.0    2.1  2  Pkinase_Tyr      Protein tyrosine kinase
  ------ inclusion threshold ------
      0.042   12.8   0.0      0.061   12.3   0.0    1.2  1  Pox_ser-thr_kin  Poxvirus serine/threonine protein kinase
      0.062   12.6   0.0       0.13   11.6   0.0    1.5  1  Kdo              Lipopolysaccharide kinase (Kdo/WaaP) family
      0.096   11.4   0.0       0.15   10.8   0.0    1.3  1  Pkinase_fungal   Fungal protein kinase


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.6   0.0   1.1e-24   3.9e-21      42     255 ..      60     349 ..      33     358 .. 0.65

  Alignments for each domain:
  == domain 1  score: 75.6 bits;  conditional E-value: 1.1e-24
                 H.....................HHHHHHHHHHHHHS...CTTB--EEEEEEE........SSEEEEEEE--TTEBHHHHHH.....HHSS--HH..... CS
     Pkinase  42 e.....................kkvlrEikilkklk...hpnivrlyevfee........kdelylvleyveggeladlle.....rkgslsee..... 98 
                 +                      ++++Eikil++     h+niv+l +   +           +++ l + +  +l+d+ +     +      +     
  EEA19867.1  60 HalaleedfvflkgrdafyarvGAMTQEIKILAREPiygHRNIVHLHSLAWDempdiglfAPMMIVELAWSQAPTLEDYFStrqnqQ-----RRdfddw 153
                 44555555555555555555556789******9976667********9888767777653333333344445555999999544433.....3334555 PP

                 ..HHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTE.....EEE-SGTTSEE.SSSSCS.........BCTTTS...CGGGS-HHHH.......T CS
     Pkinase  99 ..eakkiakqilegleylHskgiiHrDlKpeNiLidekge.....lKitDFGlake.lesssk.........ltsfvg...tseYlAPEvl.......k 170
                   ++ ++++ i+ gl+ lH+ +++H DlKp+NiL+ ++ e      Ki+DFG+a   l    +             vg   t+e+ APE+l       k
  EEA19867.1 154 gtDCYSLIADIADGLAMLHHCEVLHSDLKPSNILLFQDSEekglvAKIGDFGFADVdLVLARSldpaagsmvG---VGrgqTREWAAPEMLqsctmriK 249
                 88999******************************96666689999*******97533333334578664422...324469*********76665442 PP

                 T..SCBSHHHHHHHHHHHH.HHHHHSS-STTTSSHHHHHHHHHHT...HHHHHHHCT.....SHH...HHHTTS....-HHHHHHHHHHT-SSGCCSTT CS
     Pkinase 171 e..neyskkvDvWslGvil.yelltgkppfsgekgkekvekeldq...lekilkilg.....etkeklpeasei....seeakdllkkllkkdpkkRlt 254
                 +  + +  + D++s G+++ y +l+gk p +  +++ +  +e ++     ki ++l+     e++++++  se        ++d ++++++ dp+ R++
  EEA19867.1 250 RlaSTVPVARDIYSFGLLIaYIVLNGKSPRQLVQSDGNSIEEQNEeldRLKIDDLLQarieeEVRLHWKSGSERedenRMIVLDQIREIVTADPTARPS 348
                 1324456788******9872567899999886665554444333322235555555566655344444444333443255567889999999**99998 PP

                 H CS
     Pkinase 255 a 255
                  
  EEA19867.1 349 S 349
                 5 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.0   0.0    0.0071        25       5      48 ..      12      62 ..       8      72 .. 0.78
   2 !   57.4   0.0   3.6e-19   1.3e-15      47     245 ..      83     320 ..      69     331 .. 0.79

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.0071
                 EEEEEESSEEEEEEEEET.......TTTSSEEEEEEEEESTTSSHHHHHHH CS
  Pkinase_Tyr  5 kklGeGafGkVvegtlkg.......ekekkevkVavKtlkeeateeekeel 48
                 + lG+Ga  +V+   ++          ++++ kVavK +++e+   ++++l
   EEA19867.1 12 EYLGRGATMEVFAVDYSPqenkgseAGRSTTRKVAVKRVSREHAPVRNHAL 62
                 6799*******999999888888877788999******9776665544444 PP

  == domain 2  score: 57.4 bits;  conditional E-value: 3.6e-19
                  HHHHHHHHHHT..S.-BTTB--EEEEEESSSS......EEEEEE--..TTEBHHHHHHHTCTTTSB.H....HHHHHHHHHHHHHHHHHHHTTEEEST CS
  Pkinase_Tyr  47 elleeakimkk..l.khpnivkllgvctkeep......llivteyv..kgGdLlkfLrkkekeklt.l....kdllsfalqvAkGmeyLeskklvHrd 128
                  ++++e+ki+ +  +  h+niv+l+ +  +e p       ++++e++  +  +L+++  ++++++ + +    +d +s+++++A+G++ L++ +++H d
   EEA19867.1  83 AMTQEIKILARepIyGHRNIVHLHSLAWDEMPdiglfaPMMIVELAwsQAPTLEDYFSTRQNQQRRdFddwgTDCYSLIADIADGLAMLHHCEVLHSD 180
                  6889999998644359************998889999978888875226669*****98833332212222257899********************* PP

                  -SGGGEEEEE.....TTEEEE-STT.......THEETTTSSEEEETTSSTSGGGGS-HHHHHHSE.........EEHHHHHHHHHHHHHHHHTTSSGT CS
  Pkinase_Tyr 129 laarNvLlse.....nkvvkisDfG.......LardiekddeyvkkeeaklpvkWmapEslkekk.........ftsksDvWsfGvllwEiftlgesp 205
                  l   N+Ll +     + v+ki+DfG       Lar++       +  ++    +W apE+l++++         + ++ D++sfG l+  i+ +g+sp
   EEA19867.1 181 LKPSNILLFQdseekGLVAKIGDFGfadvdlvLARSLDPAAGSMVGVGRGQTREWAAPEMLQSCTmrikrlastVPVARDIYSFGLLIAYIVLNGKSP 278
                  ********87666657799******44444444556655555577777788899*********9988889887778899******************* PP

                  TTTS..HHHHHHHHHHTTEES-BBTTSBHHHHHHHHHHT-SS CS
  Pkinase_Tyr 206 ypgl..kneevleklkegkrlekpekcpeelyelmkkcweed 245
                   + +  + +++ e+ +e  rl+  +  ++++ e ++  w++ 
   EEA19867.1 279 RQLVqsDGNSIEEQNEELDRLKIDDLLQARIEEEVRLHWKSG 320
                  988853456677777999999999999999999888888765 PP

>> Pox_ser-thr_kin  Poxvirus serine/threonine protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   1.7e-05     0.061     299     318 ..     175     194 ..     168     212 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.7e-05
  Pox_ser-thr_kin 299 nflhvDlkPdniLifdskek 318
                        lh DlkP niL+f+++e+
       EEA19867.1 175 EVLHSDLKPSNILLFQDSEE 194
                      469************87544 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   3.6e-05      0.13     123     157 ..     160     194 ..     137     205 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 3.6e-05
         Kdo 123 llkavgrliaklhragvnHadlyaknillqqeeee 157
                 l+ +++   a lh  +v H dl + nill q+ ee
  EEA19867.1 160 LIADIADGLAMLHHCEVLHSDLKPSNILLFQDSEE 194
                 678899999********************998733 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   4.1e-05      0.15     312     358 ..     161     211 ..     155     265 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 4.1e-05
  Pkinase_fungal 312 lrDaIkghrsLflkagiLHrDiSenNilitdskke.......gerkglLiDLDl 358
                     ++D   g+  L+ ++++LH D    Nil+ ++ +e       g+     +D+Dl
      EEA19867.1 161 IADIADGLAMLH-HCEVLHSDLKPSNILLFQDSEEkglvakiGDF--GFADVDL 211
                     6788889999**.****************9665553555532222..2344444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (359 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       377  (0.0210274); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.54u 0.32s 00:00:00.86 Elapsed: 00:00:00.49
# Mc/sec: 2223.39
//
Query:       EEA19868.1  [L=531]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.4e-07   29.0   0.0      1e-06   28.3   0.0    1.3  1  Pkinase      Protein kinase domain
    5.3e-05   22.6   0.0    8.2e-05   22.0   0.0    1.2  1  Pkinase_Tyr  Protein tyrosine kinase
     0.0098   15.8   0.0      0.021   14.7   0.0    1.6  1  MAT1-1-2     Mating type protein 1-1-2 of unknown function


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.3   0.0   1.7e-10     1e-06      70     211 ..     273     439 ..     246     478 .. 0.70

  Alignments for each domain:
  == domain 1  score: 28.3 bits;  conditional E-value: 1.7e-10
                 SSEEEEEEE--TTEBHHHHHH...HHSS--HHHHH.HHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTE..............EEE-SGTTSEESSS CS
     Pkinase  70 kdelylvleyveggeladlle...rkgslseeeak.kiakqilegleylHskgiiHrDlKpeNiLidekge..............lKitDFGlakeles 150
                 k+e+ l+l y  g ++ + l+   + + l++ +++ ++++q+++++ y H  g++H+ + pe iLi ++++              l +t F la+e++ 
  EEA19868.1 273 KREVQLFLKYPAGLDMPKTLRwalTMTPLPSINTRlELCRQLATAIFYTHTSGLVHKSIRPESILIFQEQQspehanlkkdstgvLFLTGFQLAREATP 371
                 566666666666666666666554444455555555899***************************9633334555555555666*************9 PP

                 SCSBCTTTSCGG.....GS-HHHH.TTSCBSHHHHHHHHHHHHHHHHHSS..-STTTSSHHHHHHHHHH CS
     Pkinase 151 sskltsfvgtse.....YlAPEvl.keneyskkvDvWslGvilyelltgk..ppfsgekgkekvekeld 211
                 ++ ++s  g ++     Y  P     +++y+ + D++slG+ l+e+       +f  +++   +++e+ 
  EEA19868.1 372 NT-VSSTQGNQNweydiYTHPSRHtPGTRYTMAHDIYSLGINLLEIALWDsfLIFDTHERARIFNNEAL 439
                 98.8888887771222244554445789***************99876441145665555555555544 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.0   0.0   1.4e-08   8.2e-05      62     199 ..     259     417 ..     238     435 .. 0.81

  Alignments for each domain:
  == domain 1  score: 22.0 bits;  conditional E-value: 1.4e-08
                  TB--EEEEEE...SSSSEEEEEE--TTEBHHHHHHHT..CTTTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEE..............TT CS
  Pkinase_Tyr  62 nivkllgvct...keepllivteyvkgGdLlkfLrkk..ekekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlse..............nk 140
                  ++++ +g  +    ++++ + ++y +g d+ k Lr     ++  ++++ l+++ q+A ++ y ++  lvH+ ++   +L+ +              + 
   EEA19868.1 259 HVLQSVGYAYspsPKREVQLFLKYPAGLDMPKTLRWAltMTPLPSINTRLELCRQLATAIFYTHTSGLVHKSIRPESILIFQeqqspehanlkkdsTG 356
                  6666666666444444577777777777777777766434555688999*******************************9999*********99999 PP

                  EEEE-STTTHEETTTSSEEEETTSSTSGGGGS..-HHHHHHSEEEHHHHHHHHHHHHHHHH CS
  Pkinase_Tyr 141 vvkisDfGLardiekddeyvkkeeaklpvkWm..apEslkekkftsksDvWsfGvllwEif 199
                  v  ++ f Lar+ + +   +++++++  +  +  +      +++t + D++s G+ l Ei+
   EEA19868.1 357 VLFLTGFQLAREATPNTVSSTQGNQNWEYDIYthPSRHTPGTRYTMAHDIYSLGINLLEIA 417
                  9************777777777777777665411334445567****************96 PP

>> MAT1-1-2  Mating type protein 1-1-2 of unknown function
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   3.6e-06     0.021      67     105 ..     359     398 ..     321     401 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 3.6e-06
    MAT1-1-2  67 vlgGhvklkdegkkllvkv.geenWrsaplwHPlrkvPGs 105
                  l G+   +++  + ++   g++nW  +   HP r++PG+
  EEA19868.1 359 FLTGFQLAREATPNTVSSTqGNQNWEYDIYTHPSRHTPGT 398
                 55666544445555555556*******************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (531 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       597  (0.033298); expected 358.6 (0.02)
Passed bias filter:                      555  (0.0309554); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.61u 0.32s 00:00:00.93 Elapsed: 00:00:00.48
# Mc/sec: 3317.36
//
Query:       EEA19869.1  [L=401]
Description: phosphoric ester hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.7e-10   41.1   5.6    1.8e-09   38.4   5.6    2.1  1  Metallophos    Calcineurin-like phosphoesterase
    3.9e-06   27.2   0.9    4.2e-05   23.8   0.5    2.1  2  Metallophos_2  Calcineurin-like phosphoesterase superfamily d


Domain annotation for each model (and alignments):
>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.4   5.6     2e-13   1.8e-09       2     202 ..      54     292 ..      53     294 .. 0.59

  Alignments for each domain:
  == domain 1  score: 38.4 bits;  conditional E-value: 2e-13
                  EEEEEESBTBTTCCTHHHHHHHHHHHHHHHTTESEEEEESTSSSSSHHHHHHHHHHHHHHHH.TSEEEEEC-TTS....................... CS
  Metallophos   2 rilvigDlHlalgggqlddllkllddllreekpdlvllaGDlvdrgdlekellellaalvky.pipvylllGNHe....................... 75 
                  r+++i+D+H          +l++  d+   ++ dl+++aGDl ++g++ + ++  +++l  + + ++++++GNH+                       
   EEA19869.1  54 RVVCISDTH----------TLEW-PDI---PDGDLLIHAGDLCNDGSVRE-IQGTVNWLKTLpHRHKIVIAGNHDsyfdprsrleedrdkvssslani 136
                  788888888..........4443.355...577*************5555.5555555555422466********99999999999999999999999 PP

                  .....................................CHHHHHHHHHHHHHHHHHHHEHHHCEEETSEEEEEETTE.EEEEEEESECEEETHHHHHHH CS
  Metallophos  76 .....................................gfeeellnkygylgifsepwrsdaevfnnlplaslgsgs.lkvlllhGgspellvsldklg 135
                                                           + ++k++++ ++ +  ++ + ++ ++ l      +  ++l ++G  p  + ++++lg
   EEA19869.1 137 ssstasirsvdididdfeggridwshhtqtedydyaaD---DRSEKEDDQREDIHYLQHSSVTLTFPGLTPT---QrSRTLNIYGA-PQ-IPTPMPLG 226
                  99998888888877777765554444443332221111...2222222222222222222333322222222...23356666665.33.35666666 PP

                  HHHHSCHHHHCCHHHHHHHHHHTTCSEEEEEESSESS..CSSSCSCCHHHHH......HHHHHTTESEEEEESSS CS
  Metallophos 136 slnleleapepgdewlkdlekrekadwvivlgHsply..rgsgylfgdeale......dllkkygvdlvisGHtH 202
                   +  ++ +p+  ++ +       +++++i+++H p+y  r      g++             + ++ l ++GH+H
   EEA19869.1 227 PEHAFTYPPQ--QDAWTG---TIPTETDILVTHTPPYthR----DLGPNFSIgcpyllGEVWRVRPILHVFGHVH 292
                  6666666666..555555...5***************551....333333333433221122344788899**99 PP

>> Metallophos_2  Calcineurin-like phosphoesterase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.5   4.7e-09   4.2e-05       2     115 ..      54     179 ..      53     197 .. 0.62
   2 ?    1.5   0.0     0.033     3e+02      91     130 ..     247     294 ..     227     303 .. 0.80

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 4.7e-09
  Metallophos_2   2 klaiiSDlHsnldaleavlealkevgvdaiihaGDl.eeeep...e.vleellela..pvlaVrGNnD.........eevveedvlreaaelgtdl 81 
                    +++ iSD+H     + +++++  +   d++ihaGDl ++++    + ++++l+ l     +++ GN+D         e        +   +++ +l
     EEA19869.1  54 RVVCISDTH-----TLEWPDI-PDG--DLLIHAGDLcNDGSVreiQgTVNWLKTLPhrHKIVIAGNHDsyfdprsrlE--------EDRDKVSSSL 133
                    6889*****.....7888887.555..8*******97444443223588888887798999*******6665554431........3344444444 PP

  Metallophos_2  82 .......peeaelel.....agekvlliHgdpl.gvkdalaellkea 115
                            + + +++     +g +++  H+++   +++a  ++++e+
     EEA19869.1 134 anissstASIRSVDIdiddfEGGRIDWSHHTQTeDYDYAA-DDRSEK 179
                    333333333333333445557888*******874333333.333332 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.033
  Metallophos_2  91 gekvlliHgdpl.......gvkdalaellkeaeegsd.vvvcGHtHvp 130
                    ++++l++H  p+       + + +  +ll e + ++  + v+GH H +
     EEA19869.1 247 ETDILVTHTPPYthrdlgpNFSIGCPYLLGEVWRVRPiLHVFGHVHFA 294
                    4559999998889999988888888888888888888899******65 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (401 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       419  (0.02337); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.47
# Mc/sec: 2544.67
//
Query:       EEA19870.1  [L=497]
Description: mitochondrial cytochrome b2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   2.2e-125  418.3   0.1   2.7e-125  418.0   0.1    1.1  1  FMN_dh        FMN-dependent dehydrogenase
    3.9e-24   84.6   0.0    8.1e-24   83.6   0.0    1.5  1  Cyt-b5        Cytochrome b5-like Heme/Steroid binding domain
    3.7e-08   32.9   0.0    6.3e-08   32.1   0.0    1.3  1  Glu_synthase  Conserved region in glutamate synthase
    0.00026   20.1   0.0    0.00052   19.1   0.0    1.6  1  IMPDH         IMP dehydrogenase / GMP reductase domain
    0.00052   19.5   0.3     0.0012   18.3   0.1    1.6  2  NMO           Nitronate monooxygenase
  ------ inclusion threshold ------
      0.019   14.4   0.0        4.4    6.7   0.0    2.4  2  G3P_antiterm  Glycerol-3-phosphate responsive antiterminator
        0.1   12.0   2.3        1.2    8.5   0.2    2.5  3  His_biosynth  Histidine biosynthesis protein


Domain annotation for each model (and alignments):
>> FMN_dh  FMN-dependent dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  418.0   0.1    1e-128  2.7e-125       1     347 [.     119     462 ..     119     463 .. 0.93

  Alignments for each domain:
  == domain 1  score: 418.0 bits;  conditional E-value: 1e-128
                 HHCCS-HHHHHHHH--STTSHHHHHHHHGGGGEEE---SSSS-SS-B--EEETTEEESSSEEE--BSTGGGTSTTHHHHHHHHHHHHTS-EEEETT-SS CS
      FMN_dh   1 ArkrlpkkafayvaggagdevtlrenraaferirlrprvlrdvskvdlsttllGqklslPvliaPvglaklahpdgelalaraaakagipfvlstvast 99 
                 Ar+ +++ a+ay+++ga+de+t+ren++af+++ +rprvl+dv+kvd stt+lG k s+P+++ +++l kl hp+ge+ l+raa+++++++++ t+as+
  EEA19870.1 119 ARQVMKNTAWAYYSSGADDEITMRENHTAFHKVWFRPRVLVDVEKVDFSTTMLGSKTSVPFYVTATALGKLGHPEGEVVLTRAAHNHEVIQMIPTLASC 217
                 8999*********************************************************************************************** PP

                 -HHHHHHHHT..T-EEEEEE-CSSHHHHHHHHHHHHHCTESEEEEESSTSS---BHHHHHCT--BSTT-T.G.TTGGGSTSGSCCTTH..THHHHHHCC CS
      FMN_dh 100 sleevaaaae..gplwfqlyvpkdrelteellkraeaagykalvltvDtpvlgkRerdlrngfslppklklrnllqelakpewaaealkkasaaaefvg 196
                 s++e+++a +  + +w qlyv+kdr++t++++++ae+ g+kal++tvD+p lg+Re+d+r++fs   +         +++ ++  +   ++++aa+ ++
  EEA19870.1 218 SFDEIVDARKgdQVQWLQLYVNKDRAITKKIVEHAEKRGCKALFITVDAPQLGRREKDMRVKFSDTGS---------NVQASGGDSID-RSQGAARAIS 306
                 *****996442259***********************************************8865555.........22222222222.334456889* PP

                 CHB-TC--HHHHHHHHHHHSSEEEEEEE-SHHHHHHHHHTTESEEEE--GGGTSSTT---HHHCHHHHHHHH.......SS-EEEESS--SHHHHHHHH CS
      FMN_dh 197 kqldpsltwddikwlreqtklplvvKGvltaedakraveaGvdgivvSNHGGRqldgapatidvLpeiveavgg.....rievlvDgGirrGsDvlkAl 290
                 +++dpsl+w+di w+++ tk+p+++KGv+++ed+ raveaGv+g+v+SNHGGRqld+ap++i++L e++  +++     +ie+++DgGirrG+D++kAl
  EEA19870.1 307 SFIDPSLSWKDIPWFKSITKMPILLKGVQCVEDVLRAVEAGVQGVVLSNHGGRQLDFAPSAIEILAEVMPILRErgwenKIEIFIDGGIRRGTDIIKAL 405
                 ********************************************************************888874455559******************* PP

                 HTT-SEEEESHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT-SBHHHHHCGGEE CS
      FMN_dh 291 alGAdavllGRpflyglaagGeeGvervleilraelertmallGvksvaeldrslls 347
                 +lGA++v++GRpfly+++++G+eGver++++l++ele +m+l+G+++va+l++++++
  EEA19870.1 406 CLGATGVGIGRPFLYAMSTYGQEGVERAFQLLKDELEMNMRLIGAATVADLNPTMVD 462
                 ******************************************************996 PP

>> Cyt-b5  Cytochrome b5-like Heme/Steroid binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.6   0.0   3.2e-27   8.1e-24       3      72 ..       7      76 ..       5      78 .. 0.94

  Alignments for each domain:
  == domain 1  score: 83.6 bits;  conditional E-value: 3.2e-27
                HHHTTTECTTEEEEEETTEEEECTTTCCCSTTCSHHHHTTTTSBBHHHHHHTTGGCHHHHHHHHG.GEEEE CS
      Cyt-b5  3 eelskhngkndlwvairgkVYDvskflskhpGgesailkyaGkDateafksvvhsekdaekllkk.ylvGk 72
                +e+s+hn+k+++wv+++gk YDv++fl +hpGg+++ilkyaGkDate+f+ + h  + + k+l++  ++G 
  EEA19870.1  7 QEVSQHNNKDSCWVIVHGKAYDVTEFLPEHPGGQKIILKYAGKDATEEFEPI-HPRDTLDKYLDSsKHLGP 76
                79**************************************************.9999999**999888876 PP

>> Glu_synthase  Conserved region in glutamate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.1   0.0   2.5e-11   6.3e-08     259     310 ..     371     422 ..     362     426 .. 0.93

  Alignments for each domain:
  == domain 1  score: 32.1 bits;  conditional E-value: 2.5e-11
                   HHHHHHHHHHTT-GGG-EEEEESS--SHHHHHHHHHHT-SEEE-SHHHHHHT CS
  Glu_synthase 259 laevdqtlkeeglrdrvsliadGglktgadvvkalalGAdavgigtaalial 310
                   laev   l+e g  +++++++dGg++ g+d++kal lGA  vgig+  l a+
    EEA19870.1 371 LAEVMPILRERGWENKIEIFIDGGIRRGTDIIKALCLGATGVGIGRPFLYAM 422
                   899999****************************************999998 PP

>> IMPDH  IMP dehydrogenase / GMP reductase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0     2e-07   0.00052     205     239 ..     384     418 ..     366     458 .. 0.87

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 2e-07
                 TCT-EEEEES---SHHHHHHHHHTT-SEEEESCCC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       IMPDH 205 kagvpviaDGGikysgdivkAlaaGadavmlGsll 239
                 ++++++  DGGi+   di+kAl++Ga  v +G+ +
  EEA19870.1 384 ENKIEIFIDGGIRRGTDIIKALCLGATGVGIGRPF 418
                 45699*************************99865 PP

>> NMO  Nitronate monooxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0         1   2.6e+03     260     299 ..     241     284 ..     230     305 .. 0.77
   2 !   18.3   0.1   4.6e-07    0.0012     145     231 ..     336     424 ..     321     450 .. 0.74

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 1
         NMO 260 aRalatelleelee....akiatlalpeahelakkiraalveag 299
                  Ra+  +++e+ e+    a   t++ p+ + + k +r + ++ g
  EEA19870.1 241 DRAITKKIVEHAEKrgckALFITVDAPQLGRREKDMRVKFSDTG 284
                 69999999999998776666677788888888888888877763 PP

  == domain 2  score: 18.3 bits;  conditional E-value: 4.6e-07
         NMO 145 svkearkvearGaDalivqGpeaGGhqGtpevgdkglfaLvpqvldavd.......iPviAaGGiidrrgvaaaLalGAsgvqigtrfLltkes 231
                  v+++  + ++G   +++  ++ GG q ++++     ++++++v+  +        i +   GGi ++ ++  aL+lGA gv ig  fL +   
  EEA19870.1 336 CVEDVLRAVEAGVQGVVL--SNHGGRQLDFAPS---AIEILAEVMPILRergwenkIEIFIDGGIRRGTDIIKALCLGATGVGIGRPFLYAMST 424
                 555556666666666665..4677777777774...55555555555555666778999999***************************98665 PP

>> G3P_antiterm  Glycerol-3-phosphate responsive antiterminator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.0    0.0053        14     124     170 ..     311     356 ..     299     357 .. 0.89
   2 ?    6.7   0.0    0.0017       4.4     115     169 ..     363     416 ..     359     420 .. 0.84

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0053
                   SGGGHHHHCTSTTS...EEEEESS--SHHHHHHHCTT.SSEEEE--H CS
  G3P_antiterm 124 PglvpkvikeikkelkipiiaGGLietkedveealkaGaiavstsnk 170
                   P+l  k i  +k+ +k+pi+  G ++  edv +a++aG+++v  sn+
    EEA19870.1 311 PSLSWKDIPWFKSITKMPILLKG-VQCVEDVLRAVEAGVQGVVLSNH 356
                   66777778999999*********.78899*************99985 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0017
                   HT-SEEEEESGGGHHHHCTSTTS...EEEEESS--SHHHHHHHCTT.SSEEEE-- CS
  G3P_antiterm 115 skpdavevlPglvpkvikeikkelkipiiaGGLietkedveealkaGaiavstsn 169
                     p a+e+l  ++p + ++  ++ ki+i+  G i+   d+ +al  Ga++v  ++
    EEA19870.1 363 FAPSAIEILAEVMPILRERGWEN-KIEIFIDGGIRRGTDIIKALCLGATGVGIGR 416
                   5799*********9777766665.999999999*****************98766 PP

>> His_biosynth  Histidine biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       1.3   3.3e+03     149     167 ..     245     263 ..     221     292 .. 0.57
   2 ?    2.3   0.0     0.038        96     197     219 ..     331     353 ..     320     356 .. 0.76
   3 ?    8.5   0.2   0.00048       1.2      72     102 ..     385     415 ..     372     425 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1.3
                   HHHHHHHHHHTT-SEEEEE CS
  His_biosynth 149 avelakkleelgageillt 167
                   + ++++ +e++g++++ +t
    EEA19870.1 245 TKKIVEHAEKRGCKALFIT 263
                   3445555555555554433 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.038
                   ESS--SHHHHHHHHHTTCSEEEE CS
  His_biosynth 197 sGGvgsledlkelksegvdaviv 219
                     Gv+ +ed+ +++++gv++v++
    EEA19870.1 331 LKGVQCVEDVLRAVEAGVQGVVL 353
                   45899999999999999999986 PP

  == domain 3  score: 8.5 bits;  conditional E-value: 0.00048
                   -SSEEEEESSSSSHHHHHHHHHCT-SEEEES CS
  His_biosynth  72 vfipvqvGGGIrsledveelleagadkviig 102
                    +i++ ++GGIr+  d+ ++l +ga  v ig
    EEA19870.1 385 NKIEIFIDGGIRRGTDIIKALCLGATGVGIG 415
                   479999******************9999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (497 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       446  (0.0248759); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.62u 0.31s 00:00:00.93 Elapsed: 00:00:00.49
# Mc/sec: 3058.30
//
Query:       EEA19871.1  [L=314]
Description: ras-like GTP-binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.8e-40  137.6   0.0      4e-37  127.3   0.0    2.0  2  Ras          Ras family
    2.1e-30  105.4   0.0    3.2e-30  104.8   0.0    1.3  1  Roc          Ras of Complex, Roc, domain of DAPkinase
      5e-11   42.4   0.0    8.5e-11   41.6   0.0    1.4  1  Arf          ADP-ribosylation factor family
    8.9e-06   25.8   0.1    1.4e-05   25.2   0.1    1.3  1  MMR_HSR1     50S ribosome-binding GTPase
     0.0043   17.5   0.0      0.007   16.8   0.0    1.4  1  AAA_16       AAA ATPase domain
      0.008   15.6   0.0      0.013   14.9   0.0    1.3  1  SRPRB        Signal recognition particle receptor beta subuni
     0.0083   16.0   0.2       0.02   14.8   0.3    1.7  2  RsgA_GTPase  RsgA GTPase
  ------ inclusion threshold ------
      0.027   14.7   0.1       0.14   12.4   0.1    2.1  2  AAA_22       AAA domain
      0.028   13.8   0.0      0.038   13.3   0.0    1.2  1  Gtr1_RagA    Gtr1/RagA G protein conserved region
      0.069   12.9   0.0       0.12   12.0   0.0    1.5  1  AAA_24       AAA domain
       0.09   12.8   0.0       0.14   12.2   0.0    1.3  1  Dynamin_N    Dynamin family
       0.12   11.9   0.1       0.19   11.2   0.1    1.3  1  AAA_7        P-loop containing dynein motor region
       0.17   11.4   0.1       0.29   10.7   0.1    1.4  1  cobW         CobW/HypB/UreG, nucleotide-binding domain
       0.22   11.4   0.0       0.31   10.9   0.0    1.3  1  ATPase_2     ATPase domain predominantly from Archaea


Domain annotation for each model (and alignments):
>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.3   0.0   3.1e-40     4e-37       1     130 [.       8     154 ..       8     167 .. 0.89
   2 !    8.4   0.0    0.0011       1.5     139     160 ..     207     228 ..     190     230 .. 0.90

  Alignments for each domain:
  == domain 1  score: 127.3 bits;  conditional E-value: 3.1e-40
                 EEEEEESTTSSHHHHHHHHHHSSCS.SSCTTTSSEEEEEEEE..EETTEEEEEEEEEETTSGGGHHHHHHHHTTESEEEEEEETTBHHHHHTHHHHHHH CS
         Ras   1 KlvlvGdsavGKtslllrfvkdkFk.eeyesTigvdfytkei..evdgkevkleiwDTAGqeefkslrelyyrdaegillvyditsresfenvkkwvee 96 
                 K+v++G+++vGKtsl++r+vk++F+  + +sT+g+ f tk++  +++++ v+l+iwDTAGqe+f+s+ +lyyr+a+++ll+ydit+++sf++++ w++e
  EEA19871.1   8 KIVVLGSQGVGKTSLVNRYVKNSFEpAKITSTVGASFVTKRVldTTSDTIVRLQIWDTAGQERFRSISRLYYRGANACLLCYDITDENSFKEMTGWLQE 106
                 9***********************8256789*********99434558899************************************************ PP

                 HHHHST..........TTSEEEEEEETTTGGG....G-SS-HHHHHHH CS
         Ras  97 ikrvae..........envpivLvGnKvDlee....kravsteegeel 130
                 +k+             + ++i +vG+K+D+      +r+v +e+  ++
  EEA19871.1 107 LKQNLGhsndvgaggdSPLVIHVVGTKSDIVAlepsRRKVPFERTIAY 154
                 ***9988999999998889999*******9988888788877776554 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0011
                 EEEBTTTTCTHHHHHHHHHHHH CS
         Ras 139 letSAktnenveeafeellrei 160
                  e+SAk+ e+vee+f  ++r++
  EEA19871.1 207 HEISAKDGEGVEEVFRVIARKL 228
                 59*****************997 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.8   0.0   2.5e-33   3.2e-30       1     109 [.       8     114 ..       8     136 .. 0.83

  Alignments for each domain:
  == domain 1  score: 104.8 bits;  conditional E-value: 2.5e-33
                 EEEEESSTTSSHHHHHHCHCT-CCC-EE.ETTTTEEEEEEECGGSGGCTTBTTTTCEEEEEEEE-SGGCTTTT-HHHHCTSCEEEEEEE...GHHHHCH CS
         Roc   1 KvvlvGdsgvGKtsllkrfvedkfseke.kstigvdfltkevtkikgvendkkvkkvklniWDtaGqerfrslhplylreaalailvyd...srssenl 95 
                 K+v++G +gvGKtsl++r+v+++f++ + +st+g++f+tk+v   +++  ++  + v+l+iWDtaGqerfrs+ +ly+r+a++++l+yd   ++s++++
  EEA19871.1   8 KIVVLGSQGVGKTSLVNRYVKNSFEPAKiTSTVGASFVTKRVL--DTT--SD--TIVRLQIWDTAGQERFRSISRLYYRGANACLLCYDitdENSFKEM 100
                 9***********************9765389*********984..442..22..4699******************************96545567888 PP

                 HHHHHHHHHHCSSS CS
         Roc  96 keWlkelkkvagks 109
                   Wl+elk++ g+s
  EEA19871.1 101 TGWLQELKQNLGHS 114
                 99******997765 PP

>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.6   0.0   6.7e-14   8.5e-11      12     109 ..       4     109 ..       1     137 [. 0.84

  Alignments for each domain:
  == domain 1  score: 41.6 bits;  conditional E-value: 6.7e-14
                 TTEEEEEEEESTTSSHHHHHHHHHHSSCEE..CSSSSSEEEEEEEE......TTEEEEEEEE-SSGGGGGGGGGGCTTESEEEEEEETT-CTTHHHHHH CS
         Arf  12 kkelrilllGLDnaGKtTilkklkleelvt..tvPTigfnveelei......knlkftvwDvGGqeklRplWknYfektdavifvvDsadreRleeake 102
                 + e++i++lG  + GKt +++++ +++++   ++ T+g    + ++        +++++wD  Gqe+ R++ + Y++  +a + + D +d++ ++e+  
  EEA19871.1   4 SLEAKIVVLGSQGVGKTSLVNRYVKNSFEPakITSTVGASFVTKRVldttsdTIVRLQIWDTAGQERFRSISRLYYRGANACLLCYDITDENSFKEMTG 102
                 5689********************99886533888888654333223344446799****************************************998 PP

                 HHHHHCT CS
         Arf 103 eLkalle 109
                  L++l +
  EEA19871.1 103 WLQELKQ 109
                 8888755 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   0.1   1.1e-08   1.4e-05       1     101 [.       8     104 ..       8     137 .. 0.67

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 1.1e-08
                 EEEEEESTTSSHHHHHHHHHTS...TEEESSST...TSSSSEEEEEEEETT.EEEEEEECGGCSSHHHHHHHHHHHHHHHHCTSEEEEEEETT.TTCSH CS
    MMR_HSR1   1 evaivGrpNvGKStLinaltge...kaivsdkp...gtTrdinegrvklkg.keielvDtpGliegaseekglgkaflaleeadlillvvdas.eeklk 91 
                 +++++G   vGK++L+n+ +++    a+++++    ++T+ +   + +     +++++Dt+G  e   + +++++ + +   a++ ll+ d++ e+++ 
  EEA19871.1   8 KIVVLGSQGVGKTSLVNRYVKNsfePAKITSTVgasFVTKRVLDTTSD--TiVRLQIWDTAG-QE---RFRSISRLYYR--GANACLLCYDITdENSF- 97 
                 589*****************9655545555554344899999888877..4479********.44...22244444443..46677777776631222. PP

                 HHHHHHHHHH CS
    MMR_HSR1  92 pldeeleell 101
                    +e+  +l
  EEA19871.1  98 ---KEMTGWL 104
                 ...3333333 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.0   5.4e-06     0.007      27      88 ..       9      77 ..       2     170 .. 0.69

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 5.4e-06
      AAA_16 27 vllsGesGvGKsslv.rellralekd......ggiflrgkcdqlesaipy.salaqalareellrqllde 88
                +++ G +GvGK+slv r +++++e +      g+ f++ +  + +s++   +++++++ + e +r + + 
  EEA19871.1  9 IVVLGSQGVGKTSLVnRYVKNSFEPAkitstvGASFVTKRVLDTTSDTIVrLQIWDTAGQ-ERFRSISRL 77
                689************666666777778888887777777777776663332557776644.666665544 PP

>> SRPRB  Signal recognition particle receptor beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0     1e-05     0.013       4      64 ..       7      73 ..       4      87 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1e-05
                -EEEEE-STTSSHHHHHHHHHHSS---B-.--S..S-EEETTG......GGTT-SEEEETT-GCCSH CS
       SRPRB  4 pavllvGlsdsGKTslftrLttdsvkktv.tSq..essaalkv...ksekgskltliDfPGheklrq 64
                 +++++G +  GKTsl +r  ++s++++  tS   +s ++++v   +s+   +l++ D  G+e++r+
  EEA19871.1  7 AKIVVLGSQGVGKTSLVNRYVKNSFEPAKiTSTvgASFVTKRVldtTSDTIVRLQIWDTAGQERFRS 73
                57999******************666543134443444455555548888899999********996 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.3   1.5e-05      0.02      99     122 ..       7      29 ..       1      73 [. 0.75
   2 ?   -3.6   0.0         7     9e+03      81     100 ..     208     227 ..     200     229 .. 0.70

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 1.5e-05
                  TSEEEEECSTTSSHHHHHHHHCTT CS
  RsgA_GTPase  99 dktsvlvGqSGvGKStLinallpe 122
                   k +v++G+ GvGK++L+n+ + +
   EEA19871.1   7 AK-IVVLGSQGVGKTSLVNRYVKN 29 
                  44.5678************99887 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 7
                  E--TTTHTTHHHHHHHCTTS CS
  RsgA_GTPase  81 lvsaktkegleelkellkdk 100
                   +sak++eg+ee+ ++++ k
   EEA19871.1 208 EISAKDGEGVEEVFRVIARK 227
                  57888888888887777665 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   0.00011      0.14       8      48 ..       9      48 ..       5     124 .. 0.68
   2 ?   -1.1   0.0       1.6     2e+03      46      79 ..     210     240 ..     204     247 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00011
      AAA_22  8 lvvtGesGtGKTtllrrlleqldeeakaee....erpevvfvtlp 48
                +vv G  G+GKT l++r++++  e ak++           fvt  
  EEA19871.1  9 IVVLGSQGVGKTSLVNRYVKNSFEPAKITStvgaS-----FVTKR 48
                7999**************99875444444443330.....33333 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 1.6
      AAA_22  46 tlpsstsskdllrellralglelkaerlsseell 79 
                  ++ +++ ++++r ++r+l +++++   ++ el+
  EEA19871.1 210 SAKDGEGVEEVFRVIARKLVEQRNK---QLNELM 240
                 5566667888999999999988887...544444 PP

>> Gtr1_RagA  Gtr1/RagA G protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0     3e-05     0.038       1      63 [.       8      73 ..       8     117 .. 0.72

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 3e-05
   Gtr1_RagA  1 kvLLmGksgsGKtsmrsiiFdn.yl.ardtlrlgatidveks.evrflgnltlnlwDcgGqeafve 63
                k++ +G +g GKts+ +   +n +  a+ t ++ga+  +++  +      + l++wD  Gqe+f  
  EEA19871.1  8 KIVVLGSQGVGKTSLVNRYVKNsFEpAKITSTVGASFVTKRVlDTTSDTIVRLQIWDTAGQERFRS 73
                7899**********98776655144144556677665444431233445579**********9864 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   9.6e-05      0.12       2      22 ..       6      26 ..       5      62 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 9.6e-05
      AAA_24  2 klkiliyGpsgiGKTtlakel 22
                ++ki++ G++g+GKT+l++++
  EEA19871.1  6 EAKIVVLGSQGVGKTSLVNRY 26
                589***************998 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00011      0.14       1      29 [.       9      37 ..       9      84 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00011
                EEEEEBTTTTHHHHHHHHHTS--S---SS CS
   Dynamin_N  1 iavvGsqSsGKSSvlnaLlgedilprgpn 29
                i+v+Gsq  GK+S++n  ++  + p + +
  EEA19871.1  9 IVVLGSQGVGKTSLVNRYVKNSFEPAKIT 37
                89******************999996544 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.1   0.00015      0.19      34      65 ..       7      38 ..       2      58 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00015
       AAA_7 34 kpvllvGptGtGKtviikd.llkkldkekylsl 65
                 ++++ G++G+GKt+++++ + +++++ k++  
  EEA19871.1  7 AKIVVLGSQGVGKTSLVNRyVKNSFEPAKIT-S 38
                678999*************444555544443.3 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.1   0.00023      0.29       3      55 ..       9      59 ..       7      62 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00023
                EEEEESTTCCHHHHHHHHHCT--SS-EEEEESS-SSCHCCCCCCHCCCT.EEE CS
        cobW  3 tvltGflGsGKTtLlnhllenraglklavivNefgevsiDaellretgveive 55
                +v+ G+ G GKT+L+n++++n  + + a i+  +g   + +++l++t++ iv 
  EEA19871.1  9 IVVLGSQGVGKTSLVNRYVKN--SFEPAKITSTVGASFVTKRVLDTTSDTIVR 59
                6899***************87..666677777776666666666666666665 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00024      0.31      23      44 ..       9      30 ..       2     108 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00024
    ATPase_2 23 yfiYGpegsGKtaLlkeiienl 44
                +++ G++g+GKt+L+++ ++n+
  EEA19871.1  9 IVVLGSQGVGKTSLVNRYVKNS 30
                799****************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (314 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       527  (0.0293937); expected 358.6 (0.02)
Passed bias filter:                      482  (0.0268838); expected 358.6 (0.02)
Passed Vit filter:                        81  (0.00451782); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.61u 0.30s 00:00:00.90 Elapsed: 00:00:00.50
# Mc/sec: 1904.57
//
Query:       EEA19872.1  [L=474]
Description: alpha,alpha-trehalose-phosphate synthase subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   4.3e-164  546.7   0.0     5e-164  546.5   0.0    1.0  1  Glyco_transf_20  Glycosyltransferase family 20
      0.006   16.3   0.1      0.012   15.3   0.0    1.5  2  Glyco_transf_5   Starch synthase catalytic domain
  ------ inclusion threshold ------
       0.15   11.5   0.3       0.79    9.2   0.0    2.2  3  Glycos_transf_1  Glycosyl transferases group 1


Domain annotation for each model (and alignments):
>> Glyco_transf_20  Glycosyltransferase family 20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  546.5   0.0  8.3e-168    5e-164       2     473 ..       8     470 ..       7     471 .. 0.97

  Alignments for each domain:
  == domain 1  score: 546.5 bits;  conditional E-value: 8.3e-168
                      -EEEEEEE-SECEEE-S.SCG..EEECCGSSHHHHHCCCHHCCC-EEEEEEECCES-CCC..HCCCCHHHCCCCCEEEEEE-HHHHHHHCCCHH CS
  Glyco_transf_20   2 klvvvsnrlplklereseeekeeyelkkssgglvsalkglkeetevvwvgwlgvevdeseeakekvskeleekfsvvpvflsdekveeyyngfs 95 
                      +l+vvsnrlpl+++r++ +++  y+ ++ssgglv++l+gl +++e++w+gw+g++++e + ++e++ ++    ++++pvfl++e + ++yngfs
       EEA19872.1   8 NLIVVSNRLPLSVKRSE-DGS--YHSSMSSGGLVTSLSGLTKTAEFRWFGWPGMSPKEPD-EQEEIRRS-LGAHNAIPVFLDEELAYKHYNGFS 96 
                      689************98.787..999*******************************999.66777655.566789****************** PP

                      HHCHHHHHTT-GG....G----HHHHHHHHHHHHHHHHHHHCC--TT-EEEEESGGGTTHHHHHHHCCTT....SEEEEEE-S----HHHHTTS CS
  Glyco_transf_20  96 ksvLWpllHYklpdsseekefersawdaYvkvnklFAdkiveeikdgdliwvhDYhLmllPellRkkled....akigfflHiPFPsseifriL 185
                      +++LWp+lHY+        +++++aw+aY+kvn++FAd i++ ++++dliwvhDYhLmllP+llR+++ +    a igf lH+PFP+se  ++L
       EEA19872.1  97 NQILWPILHYQSG-----VTYDEEAWEAYKKVNEIFADYIADAAQEEDLIWVHDYHLMLLPKLLRERMAKkkrqACIGFSLHTPFPPSESLKVL 185
                      **********999.....9************************************************99888899******************* PP

                      TTHHHHHHHHTTSSEEEESSHHHHHHHHHHHHHHSSEEEECTTEEEEETTEEEEEEE------HHHHHHHCCSCHHHHHHHHHHHHT.TTSEEE CS
  Glyco_transf_20 186 pvreeilegllgadliGFhtedyarhFlsccsrllgleveskrggveykgrkvsvkalpigidverlesalkkesvsekvkelkerfenkkkli 279
                      pv ++il+g l+++l+GFht+dy ++F ++c+ ll+++ + +  ++ yk+r v+++ +++gid+++++++lk+++v+++++ l+er+++ +++i
       EEA19872.1 186 PVAKDILQGTLSSTLVGFHTDDYRKNFTESCEYLLNARSQDS--AILYKDRLVKTGRFTVGIDPDKFNETLKQDEVQSRIHDLNERYKD-VQVI 276
                      ***********************************8887777..89*****************************************77.8*** PP

                      EEEEEC-GGG-HHHHHHHHHHHHHH-GGGTTTEEEEEEEEB-STTSHHHHHHHHHHHHHHHHHHHHH-BTTB-SEEEEES---HHHHHHHHHH- CS
  Glyco_transf_20 280 lgvDrlDyikGvkqkllaferfLeeypelrgkvvlvqiavpsredveeyqelekeveelvgrINgefgtldytPvvylersldfeeliallaaa 373
                      +gvDrlDyikG++qkl+ fe+fL++yp+++gkv+l+q+avpsredv+eyq+le  ++ +vg+INg+f++ +y+P++yl+rs++f el+al+++a
       EEA19872.1 277 VGVDRLDYIKGLTQKLHGFEQFLTDYPKWQGKVILIQVAVPSREDVKEYQDLETAISCQVGKINGKFSKPEYSPIIYLHRSIPFTELTALYSIA 370
                      ********************************************************************************************** PP

                      SEEEE--SSBSS-CHHHHHHHCSTTT--EEEEETTBGGGGT-TTTSEEE-TT-HHHHHHHHHHHHC--HHHHHHHHHHHHHHHHHT-HHHHHHH CS
  Glyco_transf_20 374 dvllvtslRdGmnlvakeyvvcqqekkgvLiLSeFaGaaqsLkdaailvNPwdieevaeaikeaLkmseeerkkrekkllkqvskhdvqsWaes 467
                      d++l ts RdGmnlva+ey++cq++++gvL LSeFaGa+  ++d+++   P +i+e+a+ i+++L+ms+eerk r  kl k v  +++++W +s
       EEA19872.1 371 DMCLLTSSRDGMNLVAFEYIACQEQRNGVLALSEFAGASVFMADGTVQFHPANIKEMAQCIHKGLTMSKEERKVRYDKLKKFVHMNTSAKWGQS 464
                      ********************************************************************************************** PP

                      HHHHHH CS
  Glyco_transf_20 468 flselk 473
                      f++el+
       EEA19872.1 465 FVTELS 470
                      ***996 PP

>> Glyco_transf_5  Starch synthase catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0     2e-06     0.012      98     158 ..     108     163 ..      58     187 .. 0.78
   2 ?   -3.9   0.0       1.5   8.9e+03      52      92 ..     262     303 ..     252     308 .. 0.51

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 2e-06
  Glyco_transf_5  98 eg.lYgdkgedyednaerfalfsraalelleklgwkpdvihahDWhtalvpallkelykerg 158
                     +g  Y +  e +e  ++   +f+  +++++++    +d+i +hD+h +l+p ll+e  ++++
      EEA19872.1 108 SGvTYDE--EAWEAYKKVNEIFADYIADAAQE----EDLIWVHDYHLMLLPKLLRERMAKKK 163
                     3456744..67777777777999999999999....9*******************965443 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 1.5
  Glyco_transf_5  52 eleevaelskaaedevevev...ekvkvaklkkdgvdvyfldnp 92 
                     +++++ e +k++  +v v+v    ++k  + k +g + ++ d p
      EEA19872.1 262 RIHDLNERYKDV--QVIVGVdrlDYIKGLTQKLHGFEQFLTDYP 303
                     344444433333..333332224666666666666666666665 PP

>> Glycos_transf_1  Glycosyl transferases group 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0      0.95   5.7e+03     133     150 ..     105     122 ..     103     135 .. 0.74
   2 ?   -1.1   0.0       0.2   1.2e+03      10      41 ..     268     299 ..     259     310 .. 0.69
   3 ?    9.2   0.0   0.00013      0.79      81     116 ..     358     393 ..     347     448 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 0.95
                      TTTSEEEE-TT-HHHHHH CS
  Glycos_transf_1 133 dgetGllvkpnnaealae 150
                      ++++G+ ++++ +ea+++
       EEA19872.1 105 HYQSGVTYDEEAWEAYKK 122
                      888999999998888754 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.2
                      TTTTT-EEEEEESS-TTTTTHHHHHHHHHCCC CS
  Glycos_transf_1  10 gknekkkiilsvgrlekeKgvdllikafallk 41 
                      + +++  +i+ v rl++ Kg+++ ++ f+++ 
       EEA19872.1 268 ERYKDVQVIVGVDRLDYIKGLTQKLHGFEQFL 299
                      55566677778888888888887777777665 PP

  == domain 3  score: 9.2 bits;  conditional E-value: 0.00013
                      CHSSSHHHHHHCESEEEEEESSBSS-HHHHHHHHTT CS
  Glycos_transf_1  81 vsredleellknadifvlpsisEgfGivllEAmaag 116
                      ++ ++l +l+++ad+ +l+s ++g+ +v+ E++a+ 
       EEA19872.1 358 IPFTELTALYSIADMCLLTSSRDGMNLVAFEYIACQ 393
                      5567899***************************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (474 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       584  (0.0325729); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.59u 0.27s 00:00:00.86 Elapsed: 00:00:00.45
# Mc/sec: 3194.61
//
Query:       EEA19873.1  [L=341]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.8e-15   56.3   0.0    5.2e-15   55.4   0.0    1.4  1  adh_short     short chain dehydrogenase
      5e-11   42.8   0.1    8.5e-11   42.1   0.1    1.3  1  KR            KR domain
    1.5e-07   31.2   0.1    5.9e-07   29.3   0.0    1.8  2  adh_short_C2  Enoyl-(Acyl carrier protein) reductase


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.4   0.0   8.7e-19   5.2e-15       2     125 ..      33     158 ..      32     165 .. 0.88

  Alignments for each domain:
  == domain 1  score: 55.4 bits;  conditional E-value: 8.7e-19
                 EEEEESTTSHHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHT....TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGG CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvv.vdrseekleevakelkee....gakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfse 95 
                 + +vtG   G+G + ++++ k Ga+ ++ + rs +k e++ +e+ +     ++++ ++++D+ ++e+++++ ++++  l ++d + +NAGi    ++ +
  EEA19873.1  33 TYIVTGSNTGLGFESSRHINKLGAEKLImAVRSISKGETARAEILRStgreESSIEVWELDMGSHESIKNFAARVATTLPRVDGVLANAGI----MVDK 127
                 569*********************999967788888888888877666555788*************************************....5777 PP

                 CSHHH.HHHHHHHHTHHHHHHHHHHHHHHHH CS
   adh_short  96 lseee.wervievNltgvflltravlpamlk 125
                 +   e  e+++++N++g+fll ++++p++ +
  EEA19873.1 128 FRVVEgDESMLAINVVGIFLLFALLVPKLRD 158
                 7777767899*****************9874 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.1   0.1   1.4e-14   8.5e-11       2      95 ..      33     127 ..      32     140 .. 0.89

  Alignments for each domain:
  == domain 1  score: 42.1 bits;  conditional E-value: 1.4e-14
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHH.HHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE-------- CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedska.liaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdk 95 
                 ty++tG   gLG e +r++ + ga++l++  Rs ++ e+++a  +++  + + ++ev ++D  +++++++  +++ ++ p++ Gv+  Ag++ dk
  EEA19873.1  33 TYIVTGSNTGLGFESSRHINKLGAEKLIMAVRSISKGETARAeILRSTGREESSIEVWELDMGSHESIKNFAARVATTLPRVDGVLANAGIMVDK 127
                 8********************************77666666515556666689**************************************9886 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.3   0.0   9.8e-11   5.9e-07       4     119 ..      41     158 ..      38     166 .. 0.80
   2 ?   -0.9   0.0      0.16   9.8e+02     121     158 ..     190     226 ..     172     232 .. 0.68

  Alignments for each domain:
  == domain 1  score: 29.3 bits;  conditional E-value: 9.8e-11
                   TSHHHHHHHHHHHTT-E.EEEEESSGGH.HHHHHHHHHHTTSE...E..EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HH CS
  adh_short_C2   4 sgIGraiAkalaeeGae.vvltdlneea.kkrveelaeelgae...v..lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsre 93 
                    g+G++  +++++ Gae ++++ ++ ++ + + +e+ +++g+e   +   e+D  + e++++++++v+ ++ ++D+++ nagi+ + k +++e +  
    EEA19873.1  41 TGLGFESSRHINKLGAEkLIMAVRSISKgETARAEILRSTGREessIevWELDMGSHESIKNFAARVATTLPRVDGVLANAGIMVD-KFRVVEGD-- 134
                   799*************855555555555677777888888844355355************************************9.55555444.. PP

                   HHHHHHHHHTHHHHHHHHHHHHHCTS CS
  adh_short_C2  94 efdraldvnlyslfllakaalplmke 119
                     + +l++n+ ++fll   ++p +++
    EEA19873.1 135 --ESMLAINVVGIFLLFALLVPKLRD 158
                   ..56899*******999999886665 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.16
                   CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHH CS
  adh_short_C2 121 gsivnlssvgaervvpnynaygaaKaalealtrylAve 158
                   g+ +  +   + ++ +  + y+++K  ++  +r lA +
    EEA19873.1 190 GRGIFNALNDS-KTANIGDRYNVSKLLVIYACRELADK 226
                   55555554433.4444446899*********9999976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (341 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       277  (0.0154498); expected 358.6 (0.02)
Passed bias filter:                      259  (0.0144459); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.24s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2412.09
//
Query:       EEA19874.1  [L=814]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      7e-15   54.8   0.1    1.8e-14   53.4   0.1    1.7  1  Fungal_trans   Fungal specific transcription factor domain
    5.6e-06   26.4  12.0    9.3e-06   25.7  12.0    1.4  1  Zn_clus        Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.038   13.9   0.0      0.075   12.9   0.0    1.4  1  Caroten_synth  Carotenoid biosynthesis protein
       0.15   11.7   0.0       0.28   10.9   0.0    1.3  1  Yip1           Yip1 domain
        8.3    6.2   8.5       0.15   12.0   0.4    2.2  3  Myc_N          Myc amino-terminal region


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.4   0.1     5e-18   1.8e-14      13     194 ..     223     421 ..     212     491 .. 0.75

  Alignments for each domain:
  == domain 1  score: 53.4 bits;  conditional E-value: 5e-18
  Fungal_trans  13 pilhkpsflpkt...................ssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeili...hedfssp 87 
                   pi+h  +f ++                    +++n++k++    +ll++ila  a+ ++   +++++s  + +      plr ++++   + +++  
    EEA19874.1 223 PIIHTIKFQNEVnpppkavheimllttqyekFWHNPTKAPPLWVGLLFSILACVASVQQAMLSTTETSNQQPA--LPVKPLRSKTVQcliMGNYTNA 317
                   6777766666666666677777777776576777777777777788899999999999999999999999988..6679*****9998774444444 PP

  Fungal_trans  88 ssslwilqsL..lllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqin 182
                   +s  ++l++L   ll +y    ++    + ++g+ +rla ++g hr+p+   +    k +++e e+rrR w a+  lD++i++++G p++++ +  +
    EEA19874.1 318 NS--YALETLvmYLLGTYIGKPDSSFDGWFLMGTIIRLAMRMGYHRDPNTQTD---SKITPFEGEMRRRRWHAILQLDTLISFQMGMPSMIPPEFCD 409
                   44..666655223344555555568*************************995...6999999**************************99**9999 PP

  Fungal_trans 183 lpLPcddddlwe 194
                   ++ P + +d+++
    EEA19874.1 410 TESPRNLNDEDI 421
                   999987664433 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.7  12.0   2.6e-09   9.3e-06       1      35 [.      20      55 ..      20      60 .. 0.89

  Alignments for each domain:
  == domain 1  score: 25.7 bits;  conditional E-value: 2.6e-09
                SS-HHHHHCT---STSSSS-HHHHHCT..HHHCCCCT CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkkln..leCtfyse 35
                ++C++Cr +K KC+++ P C +C+k+   ++C++ s+
  EEA19874.1 20 TSCEQCRIRKAKCNRELP-CESCIKRDerATCKYASN 55
                69****************.*******9999**96655 PP

>> Caroten_synth  Carotenoid biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   2.1e-05     0.075     132     170 ..     331     369 ..     325     378 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.1e-05
  Caroten_synth 132 GafygvPlqNflGWlltglvlvlvlellwrkkaleerre 170
                    G + g P + f GW+l+g+++ l++++ +++++ +++ +
     EEA19874.1 331 GTYIGKPDSSFDGWFLMGTIIRLAMRMGYHRDPNTQTDS 369
                    89**************************99987766655 PP

>> Yip1  Yip1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   7.9e-05      0.28       9      90 ..     251     357 ..     247     364 .. 0.67

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 7.9e-05
        Yip1   9 frrlkkeppilrapdlallllalltlllgllaslnlgqtlasg......................eevqgltlssllgaiiggylgl....llglllla 81 
                 +++++++p   + p++ +ll+ +l+ + ++ +++  ++ ++++                        +++ +l +l+++++g+y+g     + g++l++
  EEA19874.1 251 YEKFWHNPT-KAPPLWVGLLFSILACVASVQQAMLSTTETSNQqpalpvkplrsktvqclimgnyTNANSYALETLVMYLLGTYIGKpdssFDGWFLMG 348
                 566666666.444555555555555555555553333333333444777888999999999666655556666677777777777669999******** PP

        Yip1  82 lllhliakl 90 
                  ++ l++++
  EEA19874.1 349 TIIRLAMRM 357
                 *****8886 PP

>> Myc_N  Myc amino-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.4   4.1e-05      0.15     223     258 ..     154     186 ..      29     243 .. 0.67
   2 ?   -1.9   0.0      0.67   2.4e+03      41      55 ..     418     432 ..     407     457 .. 0.75
   3 ?   -3.8   0.8       2.6   9.3e+03     201     209 ..     684     692 ..     635     716 .. 0.42

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 4.1e-05
       Myc_N 223 ssdskalssseedvlsesdeeeeeeeeeeeeidVVt 258
                  ++s+ ++s e+dv    ++eee+eeeeeeeid V 
  EEA19874.1 154 LAQSDIMTSPEDDVD---THEEEQEEEEEEEIDLVL 186
                 223322222222222...234455568899***995 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.67
       Myc_N  41 sEDiWKKFELLPTPp 55 
                  EDiW   E LP  +
  EEA19874.1 418 DEDIWPAIETLPPSR 432
                 69*******998433 PP

  == domain 3  score: -3.8 bits;  conditional E-value: 2.6
       Myc_N 201 aalaldppa 209
                 +++ ++pp+
  EEA19874.1 684 SKKKNQPPT 692
                 111111111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (814 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1007  (0.056166); expected 358.6 (0.02)
Passed bias filter:                      658  (0.0367003); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.71u 0.30s 00:00:01.01 Elapsed: 00:00:00.46
# Mc/sec: 5354.32
//
Query:       EEA19875.1  [L=730]
Description: plasma membrane channel protein (Aqy1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
   1.4e-108  363.7  11.8   1.6e-108  363.4  11.8    1.1  1  Anoctamin  Calcium-activated chloride channel
  ------ inclusion threshold ------
      0.021   14.0   5.7      0.043   13.0   5.7    1.4  1  MASE1      MASE1
       0.22   10.4  11.6        1.6    7.6  11.6    2.2  1  MFS_1      Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> Anoctamin  Calcium-activated chloride channel
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  363.4  11.8  2.7e-112  1.6e-108       1     447 [.     169     642 ..     169     644 .. 0.89

  Alignments for each domain:
  == domain 1  score: 363.4 bits;  conditional E-value: 2.7e-112
   Anoctamin   1 IrdyFGekiAlYFawlgfytsallppavlGlllflyglatitlfdneltvvfalfmviWatlflelWkrreaelaykWgtsdfeeeeeprpefrgelkr 99 
                 Ird FGe++++YF +l+ y+++l++pa++G+  +l+           +++v+a+++++W+++f+e+Wkr+e +la++W++s+++    ++ +f+ e + 
  EEA19875.1 169 IRDKFGEQVGFYFTFLQTYFRFLFFPALFGFSSWLML--------GYYSPVYAVINCVWCVVFVEYWKRQELDLALRWQVSGVSVLSSRNRSFKPESEV 259
                 9**********************************51........249********************************99999999999***99988 PP

   Anoctamin 100 espvtgeeefyyppwkrrlfrllvslplvllliclavvgvlilrclalqelvssvke..lls....flptvlnlvlililnevykklaiwltdlEnhrt 192
                 +++ tge ++++p++k rl r+l+++p+   +++++ +g +i +c+a+++++s+v++  l +    f+ptvl+  +++i + + ++la++lt +En++t
  EEA19875.1 260 RDEATGELRPVFPWTK-RLQRQLLQIPFA--FLAVIALGAVIATCFAIEIFISEVYNgpL-KsylvFIPTVLLSSILPIASTILTQLAKRLTIFENYET 354
                 789*********8888.99**********..5567999999999*************951.34666********************************* PP

   Anoctamin 193 qseyekslilKvflfqfvnsylslfyiaFvkgkflkypgkylr................rseecdeegcleelkeqLaiilvtkqllnnilevllPylk 275
                 ++e++ ++i K+ +++f++syl +f++aFv+ +f++++ +yl+                + ++ + ++++++l++q++++ vt q++n++le++lP++ 
  EEA19875.1 355 KEEHDVAFIQKMLVINFITSYLAIFLTAFVYIPFAHVIVPYLDvfratvrpfispedekTIHHSEFKIDPNRLQKQVIYFAVTAQIVNFFLETVLPFIL 453
                 ********************************************************9988889999******************************995 PP

   Anoctamin 276 eklkk.......kkk......esekdekeeeeskkltqaekeyelkkyedlfddYlemviqfGyvtlFsaafPlapllallnniieirldafklvtelr 361
                 ++l++       + k       s+  +++++e ++l+++++e++l++y+ ++dd  +mviqfGy++lFs+++Pl+p+ +l+nn++e+r+d+fk+++e++
  EEA19875.1 454 QRLSSrykkyseE-KaigrekASAAYDDHPDEVEFLKKVREEADLPEYD-TTDDLRQMVIQFGYLSLFSTVWPLVPVSFLFNNWLELRSDFFKICKEFK 550
                 4444433334431.1455555788888888999***************7.78*********************************************** PP

   Anoctamin 362 RpvperaesiGiWqkilealgvlavitnallialtsd...pek..dteqylsvlaarlafvvvlehvvlllkyliavlipdi..pkwvkeeik 447
                 Rpvpera++iG+W++ l +l++++ it  +l+ l  +   +++  +++ ++  +  + ++++  eh++l+++y ++ ++ +i  p+  +e+i+
  EEA19875.1 551 RPVPERADTIGPWLDTLGLLAWIGSITSPALVYLARSqglDSGdcTSSSHIRGWVFMTTIFF-SEHIYLAVRYAVEKTMAKIemPSIAQERIQ 642
                 ********************************444432332235444556666666666666.**************9999876777777766 PP

>> MASE1  MASE1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   5.7   7.2e-06     0.043     178     296 ..     273     380 ..     267     383 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 7.2e-06
       MASE1 178 lsafveqdlaplaakllllfalllllllvllllllllpfednsplayLllppvlwaAfrfgvrgaslallllavllilftaqgqgpfvqdsgaessaai 276
                 +   ++++l ++ +++l ++al  +++  ++  ++++++++  ++ yL+++p++ +   +++ + +l     + l+   t+     f +++  e++ + 
  EEA19875.1 273 WTKRLQRQLLQIPFAFLAVIALGAVIATCFAIEIFISEVYNGPLKSYLVFIPTVLLSSILPIASTIL-----TQLAKRLTI-----FENYETKEEHDVA 361
                 4455678999*********************************************************.....888888888.....8888888888889 PP

       MASE1 277 llqlflavlalvaLlvsaai 296
                 ++q +l++ +++++ ++++ 
  EEA19875.1 362 FIQKMLVINFITSY-LAIFL 380
                 *************9.77765 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6  11.6   0.00027       1.6     118     297 ..     176     389 ..     169     407 .. 0.64

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.00027
       MFS_1 118 ergraigllsagfslGa.ilgpllggllasslgWravfyilaivsllafvlfllll............................peepperkrkspkee 187
                 + g+++ +l++ f + +     +++++l+  lg+ ++  + a++ ++++v   +++                            + +++e         
  EEA19875.1 176 QVGFYFTFLQTYFRFLFfPALFGFSSWLM--LGYYSP--VYAVINCVWCV---VFVeywkrqeldlalrwqvsgvsvlssrnrsFKPESEV-------- 259
                 67777777777544444244455666666..666666..55677777766...33345568888888888888777554433332222222........ PP

       MFS_1 188 e..kgtgpaplvpawkallkdpvlw...illialllfffgfsglltllplylqevlglsglllaglllallalvgail...allagrlsdr........ 270
                 +  +  + +p++p w++ l ++ l    ++l++++l+  ++ ++ + + +++ ev++ +  l ++l++  + l++ il   + ++++l++r        
  EEA19875.1 260 RdeATGELRPVFP-WTKRLQRQLLQipfAFLAVIALG--AVIATCFAIEIFISEVYNGP--LKSYLVFIPTVLLSSILpiaSTILTQLAKRltifenye 353
                 2445566688888.99999999662332344444444..5566777778888*******..44444444444444444444678889998899999999 PP

       MFS_1 271 .........lgrrrrlllallllllaalglallavt 297
                          ++++  ++++ + l++++ ++++++++
  EEA19875.1 354 tkeehdvafIQKMLVINFITSYLAIFLTAFVYIPFA 389
                 999988888888888888888888888888888887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (730 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       667  (0.0372023); expected 358.6 (0.02)
Passed bias filter:                      402  (0.0224218); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.80u 0.34s 00:00:01.14 Elapsed: 00:00:00.57
# Mc/sec: 3827.54
//
Query:       EEA19876.1  [L=475]
Description: nuclear envelope protein Brr6, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.6e-40  138.0   3.1      2e-40  137.6   3.1    1.1  1  Brr6_like_C_C  Di-sulfide bridge nucleocytoplasmic transport 
  ------ inclusion threshold ------
          6    7.1   6.7        6.9    6.9   4.2    2.2  2  DUF5542        Family of unknown function (DUF5542)


Domain annotation for each model (and alignments):
>> Brr6_like_C_C  Di-sulfide bridge nucleocytoplasmic transport domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.6   3.1   2.3e-44     2e-40       2     131 ..     231     359 ..     230     361 .. 0.98

  Alignments for each domain:
  == domain 1  score: 137.6 bits;  conditional E-value: 2.3e-44
  Brr6_like_C_C   2 sylqllfnlllvllllylvisfvltikkDiekkleekkaellaeieeCkkeYeeNkCdpetrvpaleekCeewekCmnrdpeskverakvsaetla 97 
                    ++lql++nl+l++l++++v+sfvltik+Di++++++k++++l ei++C++ Y +N C+  +r pal++ C++we+Cm++dp+  v+ra+vs++t+ 
     EEA19876.1 231 YWLQLVWNLILFSLVTWVVVSFVLTIKQDIDHAADAKRNDILTEISTCRELYAQNSCNMASRPPALNDVCNNWERCMDQDPTR-VARATVSVQTIS 325
                    79*******************************************************************************99.************ PP

  Brr6_like_C_C  98 eiinsfvepislktllfllllllivlfvsnvafg 131
                     ii +fv++is+k++ ++ll++++++++sn++f 
     EEA19876.1 326 AIITGFVDAISFKAFSYFLLTITTITIASNWSFI 359
                    *******************************995 PP

>> DUF5542  Family of unknown function (DUF5542)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0      0.18   1.6e+03       9      53 ..     174     218 ..     168     220 .. 0.78
   2 ?    6.9   4.2   0.00077       6.9      45      66 ..     230     252 ..     222     254 .. 0.85

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.18
     DUF5542   9 dgrdGlreRrGlgeagrqqqnrevrpqsganglpkhsYWLdlWLF 53 
                 ++ d +  R G     + ++++ + + s + + p+ s W  ++ F
  EEA19876.1 174 YDSDRPSSREGNQPPSKFEKKNTESASSSSIQPPQGSTWAHFFAF 218
                 566777888888888888888888888999999999999887766 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.00077
     DUF5542  45 sYWLdl.WLFiLfDlvlFiFvYl 66 
                 sYWL+l W  iLf lv ++ v +
  EEA19876.1 230 SYWLQLvWNLILFSLVTWVVVSF 252
                 9***966*********9998866 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (475 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       774  (0.0431703); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.72u 0.37s 00:00:01.08 Elapsed: 00:00:00.58
# Mc/sec: 2486.95
//
Query:       EEA19877.1  [L=177]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (177 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       559  (0.0311785); expected 358.6 (0.02)
Passed bias filter:                      381  (0.0212505); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.60u 0.33s 00:00:00.93 Elapsed: 00:00:00.55
# Mc/sec: 975.80
//
Query:       EEA19878.1  [L=156]
Description: hypothetical protein PMAA_006460 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (156 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       462  (0.0257683); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.29s 00:00:00.78 Elapsed: 00:00:00.48
# Mc/sec: 971.06
//
Query:       EEA19879.1  [L=174]
Description: acetyltransferase, GNAT family, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.5e-15   55.6   0.0    6.9e-15   55.3   0.0    1.2  1  Acetyltransf_1   Acetyltransferase (GNAT) family
    6.7e-08   32.4   0.0    1.1e-07   31.7   0.0    1.3  1  FR47             FR47-like protein
    1.7e-05   24.8   0.0    2.3e-05   24.3   0.0    1.2  1  Acetyltransf_10  Acetyltransferase (GNAT) domain
    3.1e-05   24.3   0.0    4.5e-05   23.8   0.0    1.3  1  Acetyltransf_7   Acetyltransferase (GNAT) domain
     0.0002   22.1   0.0    0.00024   21.8   0.0    1.1  1  Acetyltransf_3   Acetyltransferase (GNAT) domain
  ------ inclusion threshold ------
      0.029   14.5   0.0       0.16   12.1   0.0    1.9  1  Acetyltransf_4   Acetyltransferase (GNAT) domain


Domain annotation for each model (and alignments):
>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.3   0.0   2.3e-18   6.9e-15      36     116 ..      64     150 ..      25     151 .. 0.82

  Alignments for each domain:
  == domain 1  score: 55.3 bits;  conditional E-value: 2.3e-18
                     EEEEET....TEEEEEEEEEEEET..TSTTEEEEEEEEESGGGTTSSHHHHHHHHHHHHHHHTTESEEEEEEETTEHHHHHHHHH.TT CS
  Acetyltransf_1  36 lvaeed....geliGfisllkipd..ekggvayieslaVspeyrgkGlGsaLlealeerareegikkivlaveedndaairlYek.lG 116
                     + a+ +    + ++G++ ++ ++    + + +y+e+l+V p +rgkG+G aL ++l++++ + g+k++++ v ++n+++i++Y k  G
      EEA19879.1  64 YTALVIppgsEVPVGMALYFYNYStwRSAPGIYLEDLYVQPVARGKGYGLALFKYLAKEVVRIGGKRLEWSVLKWNEPSIKFY-KaIG 150
                     333333333477**************9999*****************************************************.5476 PP

>> FR47  FR47-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.7   0.0   3.7e-11   1.1e-07      22      80 ..      95     154 ..      86     161 .. 0.87

  Alignments for each domain:
  == domain 1  score: 31.7 bits;  conditional E-value: 3.7e-11
                 SSEEEEEE-GGG-SSSHHHHHHHHHHHHHHH.S-S-EEEEEETT-HHHHHHHHHHT-EEE CS
        FR47  22 gelgalqvlpehrrrGlgsrlvkalakeiae.rgktvllvvvasNtpsirlyeklGfeki 80 
                  +l  l+v+p +r++G+g  l k lake+++  gk +   v   N+psi++y+++G +++
  EEA19879.1  95 IYLEDLYVQPVARGKGYGLALFKYLAKEVVRiGGKRLEWSVLKWNEPSIKFYKAIGAREM 154
                 57889**************************7777777888888************9987 PP

>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.3   0.0   7.8e-09   2.3e-05      40     108 ..      74     153 ..      48     160 .. 0.85

  Alignments for each domain:
  == domain 1  score: 24.3 bits;  conditional E-value: 7.8e-09
  Acetyltransf_10  40 gkivGviel.rdgs........hisllfVdpeyrgqGigkaLleaveeeaekdgikl.eltvnasp.yavpfYeklGFka 108
                      + +vG++ + ++ s        +++ l+V+p +rg+G+g aL++++ +e+ + g+k  e +v + +   ++fY+ +G ++
       EEA19879.1  74 EVPVGMALYfYNYStwrsapgiYLEDLYVQPVARGKGYGLALFKYLAKEVVRIGGKRlEWSVLKWNePSIKFYKAIGARE 153
                      55677776667777777777889**************************999999999999999998********99665 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.0   1.5e-08   4.5e-05      16      73 ..      78     150 ..      59     150 .. 0.65

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 1.5e-08
                     EEEEEEEES........TCTEEEEE-GGGTTSSHHHHHHHH..TT....SEEEEEEEEE..THHHHHHHHHHTT CS
  Acetyltransf_7  16 Gfialslld........aeitrlaVdpeyrgkGiGraLlea..ae....kgiileqlel..naekaikfYeklG 73 
                     G++ +  +          +++ l+V p +rgkG+G aL ++  +e     g +le + l  n+ ++ikfY+  G
      EEA19879.1  78 GMALYFYNYstwrsapgIYLEDLYVQPVARGKGYGLALFKYlaKEvvriGGKRLEWSVLkwNE-PSIKFYKAIG 150
                     5444444445555655556666******************75421333322223422333333.89****9877 PP

>> Acetyltransf_3  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   0.0   8.2e-08   0.00024       3     137 ..       6     151 ..       5     152 .. 0.74

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 8.2e-08
  Acetyltransf_3   3 lLrplteeDlealfe.lrsdpevmry.lpe....pltleeaeewlera..waeeseeegygwaivlkdtgv.iGsv.glrdleeedee..aelg. 84 
                     ++r +te+D++ +++ +r+  + +++   +    p++l ++ ++ +++   +++++++ y+ +++ ++++v +G++  +++++ ++ +  + l+ 
      EEA19879.1   6 TIRLATEKDVDYILQfIRELADYEKAlD-QveatPASLLATLSFPDSSpeSQQKKKGSTYTALVIPPGSEVpVGMAlYFYNYSTWRSApgIYLEd 99 
                     5889999998888884555555777642.2322355555566666555555555555557766656777788****7777999998877744444 PP

  Acetyltransf_3  85 ymlapsfwgkGyateavralleyafeelglerlvavidkeNeaSirvleklGf 137
                     ++++p ++gkGy+    + l + +  + g +rl++ + k Ne Si+ ++ +G 
      EEA19879.1 100 LYVQPVARGKGYGLALFKYLAKEV-VRIGGKRLEWSVLKWNEPSIKFYKAIGA 151
                     788899**************9999.788899******************9996 PP

>> Acetyltransf_4  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   5.4e-05      0.16      81     133 ..      99     150 ..       7     161 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 5.4e-05
  Acetyltransf_4  81 svylaerdnnkeglgrelidaleqvlkeqnienllaeiaspnensiqfhkalG 133
                       y++   ++ +g+g +l ++l +   + + ++l+ ++ + ne+si+f+ka+G
      EEA19879.1  99 DLYVQ-PVARGKGYGLALFKYLAKEVVRIGGKRLEWSVLKWNEPSIKFYKAIG 150
                     45775.678999****************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (174 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       345  (0.0192426); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.45
# Mc/sec: 1153.55
//
Query:       EEA19880.1  [L=1178]
Description: vesicle-mediated transport protein (Imh1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.1e-16   59.5   0.4    5.1e-16   58.3   0.4    1.7  1  GRIP            GRIP domain
    8.2e-05   22.0  20.7    8.2e-05   22.0  20.7   10.4 10  GAS             Growth-arrest specific micro-tubule binding
    0.00065   17.4  53.7    0.00065   17.4  53.7    4.8  5  DUF3584         Protein of unknown function (DUF3584)
    0.00067   18.6 165.2     0.0043   16.0  21.9    8.6  8  Spc7            Spc7 kinetochore protein
     0.0022   18.2  25.8     0.0022   18.2  25.8   10.0  8  Tropomyosin_1   Tropomyosin like
     0.0031   17.6  15.8     0.0031   17.6  15.8   10.6  9  CENP-F_leu_zip  Leucine-rich repeats of kinetochore protein C
     0.0043   16.4  12.6     0.0043   16.4  12.6    7.2  5  DUF4763         Domain of unknown function (DUF4763)
     0.0085   16.3  11.9     0.0085   16.3  11.9   12.1 13  Seryl_tRNA_N    Seryl-tRNA synthetase N-terminal domain
  ------ inclusion threshold ------
      0.011   15.7   1.7      0.011   15.7   1.7   12.0 12  Cep57_CLD_2     Centrosome localisation domain of PPC89
      0.018   14.8   0.9      0.018   14.8   0.9   15.7 17  DivIC           Septum formation initiator
      0.078   13.2  97.3      0.031   14.5   5.0    9.0  8  Fib_alpha       Fibrinogen alpha/beta chain family
       0.39   11.1 160.1        1.2    9.5   9.7    8.7  8  Fez1            Fez1


Domain annotation for each model (and alignments):
>> GRIP  GRIP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.3   0.4   3.4e-19   5.1e-16       5      44 .]    1132    1171 ..    1128    1171 .. 0.95

  Alignments for each domain:
  == domain 1  score: 58.3 bits;  conditional E-value: 3.4e-19
        GRIP    5 eYLKNVllqFLeskeaserkqLvpVlstlLkfspeEeqkl 44  
                   YLKNVllqFLe+k+++ +kqL+pVl++lL+f++ +eqk+
  EEA19880.1 1132 IYLKNVLLQFLEQKDKNYQKQLIPVLAMLLHFDRTDEQKW 1171
                  5**************************************8 PP

>> GAS  Growth-arrest specific micro-tubule binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.6      0.07     1e+02      83     136 ..     114     167 ..      98     180 .. 0.85
   2 ?    2.5  13.2     0.055        82      47     121 ..     194     268 ..     189     270 .. 0.91
   3 ?    2.1  27.0      0.07     1e+02      34     171 ..     253     392 ..     252     402 .. 0.81
   4 ?    3.5   0.9     0.026        39      30      88 ..     404     462 ..     402     469 .. 0.88
   5 !   10.1  12.0   0.00024      0.37      47     130 ..     563     646 ..     546     661 .. 0.75
   6 !   22.0  20.7   5.5e-08   8.2e-05      28     142 ..     663     777 ..     660     781 .. 0.96
   7 ?    2.5   9.0     0.053        79      36      88 ..     786     838 ..     778     840 .. 0.82
   8 !    6.0   5.5    0.0046       6.9      31      81 ..     844     894 ..     840     899 .. 0.92
   9 !    9.6  16.7   0.00036      0.54      53     138 ..     919    1005 ..     896    1013 .. 0.87
  10 !    5.7   8.8    0.0056       8.4      81     130 ..    1011    1060 ..    1001    1064 .. 0.63

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.07
         GAS  83 dkqslknlkarlkelekelkdlkwehevleqrfekvekerdelykkfeaaiqev 136
                 +k++ ++ k + +e+ ++  +l  e +++  r++k+e+ +++l+k +++a   v
  EEA19880.1 114 KKEAGEEGKDKATESAEKPPELPIEVRSKLRRLDKIESRYNDLHKAYKMAHARV 167
                 47777888999999999999*************************999987766 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.055
         GAS  47 kelseisqenkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkelekelkdlkwehevleqrfekveke 121
                   l+++s +n  l+++Lk+++ +++  +k+l++ ek  ++     a lke+++  k l+++ e ++ + ek e+e
  EEA19880.1 194 EYLNQMSLKNDMLMDELKRVTSDRDDFKKKLATAEKATKEALDEVATLKEQKQSEKGLEEKEEKKKTETEKPESE 268
                 568999******************************9999999999******************99999987765 PP

  == domain 3  score: 2.1 bits;  conditional E-value: 0.07
         GAS  34 eieelkkkeer..nekelseisqenkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkelekelkdlkwehevleqrfekvekerdelykkfe 130
                 e ee+kk e++   + ++    +e  rl+ ++++ +ee+e+L  ++   +k k +l+ +++  +++   l++++ e e l++  +k e+e +el+++ +
  EEA19880.1 253 EKEEKKKTETEkpESEDFFSFDNEIPRLESEVQEKQEEIEKLSTEV---DKLKRDLTVARESTESMVITLESTTRELEGLRDFKDKHESELEELKSTKQ 348
                 55566655544115778999999***********999999998765...6777899******************************************* PP

         GAS 131 aaiqevqqktglknllLekklkalqe...elEkkeaqleevlaa 171
                 + i++++ k +  +  +ek  ++l+e   +l +k ++++ + ++
  EEA19880.1 349 KEIDDIKSKLESAESAVEKSTTELSEvkrQLTEKSEEIDRLKTE 392
                 ******************98766665222677777777666554 PP

  == domain 4  score: 3.5 bits;  conditional E-value: 0.026
         GAS  30 slKeeieelkkkeernekelseisqenkrlkepLkkaeeeveeLrkqlknyekdkqslk 88 
                 +l e+i  ++k ++ +ek+l  i+   ++lk ++k  ee +  Lr +l+  +++  +l+
  EEA19880.1 404 ELNEKISLIEKDKADKEKRLGVIEGLVNKLKSQVKDGEETISSLRTDLAGKSNQVGELE 462
                 6889999999999999****************************999998888877776 PP

  == domain 5  score: 10.1 bits;  conditional E-value: 0.00024
         GAS  47 kelseisqenkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkelekelkdlkwehevleqrfekvekerdelykkfe 130
                  ++++++++ ++l+e+L++ e+ +++L+++lk  +  k+++++l+ +l +  +e  + k + + l  + +++e++r +++k+  
  EEA19880.1 563 ADVAALEKKIEELTEQLTEKEAAIDRLHAKLKGEDDLKEEIESLRDELLNIGQEHVEAKDQVKTLLVEKAALEEARAKIEKEVV 646
                 5688999*************************9999999999999888776666666666666666555555555555555443 PP

  == domain 6  score: 22.0 bits;  conditional E-value: 5.5e-08
         GAS  28 IkslKeeieelkkkeernekelseisqenkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkelekelkdlkwehevleqrfekvekerdely 126
                  + lK e eelk k +  ek+ls+++q   +  + L+ +++ +++L  +lkn + + ++lk +k++l++    +k+l+ +he l+ +++++++++ + +
  EEA19880.1 663 HTDLKAEFEELKHKSTTLEKDLSAAQQLAASRFKDLTDLKNTMQKLSPELKNLRAESAELKTTKEELNKKVADFKKLENKHEDLRAEVKSLKSSIADRE 761
                 578************************************************************************************************ PP

         GAS 127 kkfeaaiqevqqktgl 142
                 ++ ++  q+++q+t+ 
  EEA19880.1 762 NEVKTLNQKIRQETDS 777
                 **********999975 PP

  == domain 7  score: 2.5 bits;  conditional E-value: 0.053
         GAS  36 eelkkkeernekelseisqenkrlkepLkkaeeeveeLrkqlknyekdkqslk 88 
                    k   ++ e + +++ +  +r +  L +a+ee+++Lr+++++ e++  +l+
  EEA19880.1 786 SVVKSDLRQSETRKQQAVETQERTSRDLSRAQEELKNLRAKMREVEEKSTQLD 838
                 55677778888888999999999999999999999999999999999888876 PP

  == domain 8  score: 6.0 bits;  conditional E-value: 0.0046
         GAS  31 lKeeieelkkkeernekelseisqenkrlkepLkkaeeeveeLrkqlknye 81 
                 l+eei+ + ++ ++++ ++  +  + +++  ++k+a+e +e L+++l++ +
  EEA19880.1 844 LREEIQLKTAQHASAQSLMTSMRDQTSEMAMQMKEARERCESLEEELAEAH 894
                 899******************************************999876 PP

  == domain 9  score: 9.6 bits;  conditional E-value: 0.00036
         GAS   53 sqenkrlkepLkkaeeeveeLrkqlknyekdkq.slknlkarlkelekelkdlkwehevleqrfekvekerdelykkfeaaiqevqq 138 
                   ++ ++ ke L++a ee+++ + ++++  + ++ +l++lk++++e+ek lk+ + ++e le      ++ rd+l+ + e++ qev++
  EEA19880.1  919 DAKVRDFKERLEAAIEERDKAEDEANTMGRRRArELEELKTKVRETEKALKAAENDKEELEYAQRDWKRRRDDLELQAERSAQEVKE 1005
                  4678999********************98877537**********************************************999987 PP

  == domain 10  score: 5.7 bits;  conditional E-value: 0.0056
         GAS   81 ekdkqslknlkarlkelekelkdlkwehevleqrfekvekerdelykkfe 130 
                   + + +l++++++++e+eke ++l+ + e  + r+ek+ k+ ++l+++f 
  EEA19880.1 1011 VQLRDALDESERQVREMEKEKSELRRSIEETNNRLEKLRKANKALTDEFS 1060
                  33455677777777777777777777777777777777777777777765 PP

>> DUF3584  Protein of unknown function (DUF3584)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6  34.7   1.2e-05     0.018     177     460 ..     141     433 ..     138     463 .. 0.71
   2 ?   -5.0  12.0       2.5   3.7e+03     282     369 ..     525     612 ..     491     625 .. 0.69
   3 !   17.4  53.7   4.3e-07   0.00065     247     534 ..     617     898 ..     609     903 .. 0.92
   4 ?   -2.6  29.7      0.45   6.7e+02     377     519 ..     914    1052 ..     898    1069 .. 0.41
   5 ?   -1.0   0.1      0.16   2.4e+02     521     553 ..    1141    1173 ..    1133    1175 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.2e-05
     DUF3584 177 srlrhidklvkav..iekelkfetlksmivaileealadgvvpeksrlkkqdveeWiediqalaa.iekvrpeieklqeefeqleslelrLsllkgelk 272
                 s+lr +dk+ +    + k+ k+   + ++++++e    +++ p +s   ++  +e+++++ + ++ ++ + ++++    +f++     +++   + + +
  EEA19880.1 141 SKLRRLDKIESRYndLHKAYKMAHARVLLIESFES-ALRENTPLTSIGDPKALTEYLNQMSLKNDmLMDELKRVTSDRDDFKKKLATAEKATKEALDEV 238
                 5677778877654226899***************9.556669*9***************9877652566666676666666655554444444333333 PP

     DUF3584 273 adeerlaekqe..evqeakaelkqqlrtled..elkeaidelnqelsaakaklaakeselealeeqkkkyed......adieklkadldqlpsirsele 361
                 a+ ++ +++ +  e +e+k++ +++  + ed   + ++i +l++e++++++++++ + e+++l+++     +        +e+   +l+ l  +++++e
  EEA19880.1 239 ATLKEQKQSEKglEEKEEKKKTETEKPESEDffSFDNEIPRLESEVQEKQEEIEKLSTEVDKLKRDLTVAREstesmvITLESTTRELEGLRDFKDKHE 337
                 333333333220122333333333333444423577888999999999999999999999999887654433111112579****************** PP

     DUF3584 362 eleeeldaltek.hqdvqekydrrkqkikeeleeeleklkerleaireekdrlkaaieealealesqlrkqleaqkeelneeekelesrlselklrlds 459
                    eel+   +k + d+++k++  +++++++  +el++ k +l + +ee drlk+++ +a ++++ +   +l+++++ +++++++ e+rl+  + ++++
  EEA19880.1 338 SELEELKSTKQKeIDDIKSKLESAESAVEKST-TELSEVKRQLTEKSEEIDRLKTEAANATSQVNTS---ELNEKISLIEKDKADKEKRLGVIEGLVNK 432
                 999999988654389***********998876.56777788888999*********99999999854...34577778888888888888777777665 PP

     DUF3584 460 a 460
                  
  EEA19880.1 433 L 433
                 4 PP

  == domain 2  score: -5.0 bits;  conditional E-value: 2.5
     DUF3584 282 qeevqeakaelkqqlrtledelkeaidelnqels.aakaklaakeselealeeqkkkyedadieklkadldqlpsirseleeleeelda 369
                  +  +++k+++k+  +++e+ +ke+ +e + e    + a++aa e+++e+l eq  + ++a i++l+a+l  ++ +++e+e l  el  
  EEA19880.1 525 GAGGKKKKNKKKKGKQAEEAPIKETPEEPETEAAmIETADVAALEKKIEELTEQLTE-KEAAIDRLHAKLKGEDDLKEEIESLRDELLN 612
                 344556666666677777777888777766554414567888888888888888877.5677888888888888888888877776644 PP

  == domain 3  score: 17.4 bits;  conditional E-value: 4.3e-07
     DUF3584 247 ieklqeefeqleslelrLsllkgelkadeerlaekqeevqeakaelkqqlrtledelkeaidelnqelsaakaklaakeselealeeqkkkyedadiek 345
                   + + ++++l +  + L    ++++++  +l+ + +   + + +l++ l+++ +elk ++ +l+++lsaa++  a   ++l  l++  +k    ++ +
  EEA19880.1 617 HVEAKDQVKTLLVEKAALEEARAKIEKEVVELRMNHASASADSDKLHTDLKAEFEELKHKSTTLEKDLSAAQQLAASRFKDLTDLKNTMQKL-SPELKN 714
                 556678899999999999999***************************************************99999999*****9999985.678*** PP

     DUF3584 346 lkadldqlpsirseleeleeeldaltekhqdvqekydrrkqkikeeleeeleklkerleaireekdrlkaaieealealesqlrkqleaqkeelneeek 444
                 l+a+  +l  +++el++  ++++ l++kh+d+ ++ + +k+ i ++ e+e+++l+++   ir+e d  + ++ee l+ ++s lr q e  k+++ e ++
  EEA19880.1 715 LRAESAELKTTKEELNKKVADFKKLENKHEDLRAEVKSLKSSIADR-ENEVKTLNQK---IRQETDS-RLKAEESLSVVKSDLR-QSETRKQQAVETQE 807
                 *******************************************876.5678888888...9999999.7788999*********.99999999999999 PP

     DUF3584 445 elesrlselklrldsatate.Eeleqieeadealekaqeelekaeaevealqaeeeqlrkkrdeadealqkaerrleqlrqaleeleeqls 534
                 +  + ls+++  l++  a+  E  e+ ++ d++l+  +ee++  +a+  ++q+  + +r +  e   ++++a++r e l ++l+e+++ l+
  EEA19880.1 808 RTSRDLSRAQEELKNLRAKMrEVEEKSTQLDRELSGLREEIQLKTAQHASAQSLMTSMRDQTSEMAMQMKEARERCESLEEELAEAHRLLT 898
                 *************99998751666778999*********************************************************9987 PP

  == domain 4  score: -2.6 bits;  conditional E-value: 0.45
     DUF3584  377 vqekydrrkqkikeeleeeleklkerleaireekdrlkaaieealealesqlrkqleaqkeelneeekelesrlselklrldsatateEeleq.iee 472 
                  ++ ++d+++   ke+le+++e++++      +e+++   +   +le+l+ + r + e++ ++++++++ele +    k r+d+   + E + q  +e
  EEA19880.1  914 IEGRTDAKVRDFKERLEAAIEERDKA----EDEANTMGRRRARELEELKTKVR-ETEKALKAAENDKEELEYAQRDWKRRRDDLELQAERSAQeVKE 1005
                  33333333333333333333333222....33333333333444555555555.4444444444444444444444444444444444443330223 PP

     DUF3584  473 adealekaqeelekaeaevealqaeeeqlrkkrdeadealqkaerrl 519 
                    +a+ + + +l ++e +v++ ++e+ +lr   +e +++l+k +++ 
  EEA19880.1 1006 VRQAMVQLRDALDESERQVREMEKEKSELRRSIEETNNRLEKLRKAN 1052
                  33344444444444444444444444444444444333333333222 PP

  == domain 5  score: -1.0 bits;  conditional E-value: 0.16
     DUF3584  521 qlrqaleeleeqlsPqagsLlefLrkeapdWee 553 
                   l q++++ ++ql+P    Ll+f r+++++W +
  EEA19880.1 1141 FLEQKDKNYQKQLIPVLAMLLHFDRTDEQKWMN 1173
                  567889999**********************76 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.4  20.3    0.0095        14     144     265 ..     206     334 ..     198     336 .. 0.78
   2 !   16.0  21.9   2.9e-06    0.0043     142     254 ..     292     404 ..     288     409 .. 0.75
   3 ?    2.5   0.9     0.037        55     147     235 ..     408     464 ..     402     473 .. 0.48
   4 !    5.4  19.5    0.0049       7.3     157     280 ..     564     682 ..     548     682 .. 0.82
   5 !   15.8  19.2   3.3e-06     0.005     139     255 ..     661     776 ..     658     781 .. 0.87
   6 !   11.2  23.2   8.2e-05      0.12     143     261 ..     780     901 ..     778     910 .. 0.92
   7 ?   -0.9  15.6      0.38   5.7e+02     158     252 ..     911    1005 ..     903    1010 .. 0.61
   8 !    5.7  11.3    0.0038       5.7     209     264 ..     997    1052 ..     982    1062 .. 0.77

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.0095
        Spc7 144 leenlegleedkelLekqeeeldellpeleeekaeleeeleklqe.......aaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleek 235
                 l ++l+ +++d++  +k+ + ++++ +e   e a+l+e+ ++++        +++e e+ ++e+  ++ +e+ +l++e++ek++e+++l +++++l+ +
  EEA19880.1 206 LMDELKRVTSDRDDFKKKLATAEKATKEALDEVATLKEQKQSEKGleekeekKKTETEKPESEDFFSFDNEIPRLESEVQEKQEEIEKLSTEVDKLKRD 304
                 4566677777777777777777776666666666666666555544444545777777888999*********************************** PP

        Spc7 236 ieelkeqkseleeeiaeaervleeckgwse 265
                 ++ ++e+ +++   +++  r le  +++++
  EEA19880.1 305 LTVARESTESMVITLESTTRELEGLRDFKD 334
                 *********999999999999998888775 PP

  == domain 2  score: 16.0 bits;  conditional E-value: 2.9e-06
        Spc7 142 egleenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelk 240
                 e+l+ ++++l++d ++  ++ e +   l+++++e + l++  +k +++ eel+s +++e+  ++++l+++++ +e+  +el+e+++ql+e++e+i+ lk
  EEA19880.1 292 EKLSTEVDKLKRDLTVARESTESMVITLESTTRELEGLRDFKDKHESELEELKSTKQKEIDDIKSKLESAESAVEKSTTELSEVKRQLTEKSEEIDRLK 390
                 34455555555555555555555555555555555555555555555777778899******************************************* PP

        Spc7 241 eqkseleeeiaeae 254
                 ++ +++ ++++ +e
  EEA19880.1 391 TEAANATSQVNTSE 404
                 ******99998765 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.037
        Spc7 147 nlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleek 235
                 +++ +e+dk+  ek+                                  + +  +++l++++++ +++i++++++la + +q+ ele+ 
  EEA19880.1 408 KISLIEKDKADKEKRLG--------------------------------VIEGLVNKLKSQVKDGEETISSLRTDLAGKSNQVGELEKI 464
                 33333333333333333................................3344455555555555555555555555555555555554 PP

  == domain 4  score: 5.4 bits;  conditional E-value: 0.0049
        Spc7 157 lLekqeeeldellpeleeekaeleeeleklqeaaeelesid.keeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeae 254
                  +++ e++++el ++l+e++a++ + ++kl+      e+ d kee+e+lr+el ++ +e  e k+++++l  ++++lee+ ++++++  el+ + a+a 
  EEA19880.1 564 DVAALEKKIEELTEQLTEKEAAIDRLHAKLKG-----ED-DlKEEIESLRDELLNIGQEHVEAKDQVKTLLVEKAALEEARAKIEKEVVELRMNHASAS 656
                 44444555555555555555555555555555.....22.359******************************************************** PP

        Spc7 255 rvleeckgwsesevsrlkeevkalee 280
                    ++ +   + e ++lk +  +le+
  EEA19880.1 657 ADSDKLHTDLKAEFEELKHKSTTLEK 682
                 ********************999985 PP

  == domain 5  score: 15.8 bits;  conditional E-value: 3.3e-06
        Spc7 139 gLkegleenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekie 237
                 +L + l+ ++e+l++ +++Lek+ + +++l  +  +  ++l+++++kl  + ++l + +++eL++++eel++  a+ +++++++++l++++++l+++i+
  EEA19880.1 661 KLHTDLKAEFEELKHKSTTLEKDLSAAQQLAASRFKDLTDLKNTMQKLSPELKNLRA-ESAELKTTKEELNKKVADFKKLENKHEDLRAEVKSLKSSIA 758
                 688889999999999999999999999999999999999999999999987777655.78999999999999999999999999999999999999999 PP

        Spc7 238 elkeqkseleeeiaeaer 255
                 + +++ ++l+++i+++ +
  EEA19880.1 759 DRENEVKTLNQKIRQETD 776
                 999999999999998765 PP

  == domain 6  score: 11.2 bits;  conditional E-value: 8.2e-05
        Spc7 143 gleenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeeles..id.keeLeelreelaelkaeieekkkelaelqeqleeleekiee 238
                 ++ee l+ +++d ++ e +++++ e  +++++  ++ +eel++l+++ +e+e+   +   eL  lree++   a+ ++ +  ++++++q  e + +++e
  EEA19880.1 780 KAEESLSVVKSDLRQSETRKQQAVETQERTSRDLSRAQEELKNLRAKMREVEEksTQlDRELSGLREEIQLKTAQHASAQSLMTSMRDQTSEMAMQMKE 878
                 57899999**************************************88888775444688*************************************** PP

        Spc7 239 lkeqkseleeeiaeaervleeck 261
                 ++e++++leee+aea r+l e+ 
  EEA19880.1 879 ARERCESLEEELAEAHRLLTERS 901
                 *****************998764 PP

  == domain 7  score: -0.9 bits;  conditional E-value: 0.38
        Spc7  158 LekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiae 252 
                  L++ e   d+ + +++e+ ++  ee +k +++a+ +      eLeel+ +++e ++ +++ +++ +el+    + + + ++l+ q ++  +e++e
  EEA19880.1  911 LNEIEGRTDAKVRDFKERLEAAIEERDKAEDEANTMGRRRARELEELKTKVRETEKALKAAENDKEELEYAQRDWKRRRDDLELQAERSAQEVKE 1005
                  55555555555666666666666677777777777777777777777777777777777766666666665555555555555555555555554 PP

  == domain 8  score: 5.7 bits;  conditional E-value: 0.0038
        Spc7  209 aelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaervleeckgws 264 
                  ++  +e++e ++ + +l++ l+e+e ++ e++++ksel+  i+e ++ le+ ++ +
  EEA19880.1  997 ERSAQEVKEVRQAMVQLRDALDESERQVREMEKEKSELRRSIEETNNRLEKLRKAN 1052
                  45567888888888888888888888888888888888888888888888777654 PP

>> Tropomyosin_1  Tropomyosin like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4  19.9     0.026        39      24      96 ..     338     423 ..     329     424 .. 0.81
   2 ?    4.0   4.7     0.035        52       3      74 ..     387     460 ..     385     471 .. 0.80
   3 ?   -2.2  14.6       2.8   4.1e+03      57     118 ..     545     608 ..     529     621 .. 0.63
   4 ?    5.3  11.6     0.013        20       4      77 ..     665     738 ..     661     742 .. 0.90
   5 !   18.2  25.8   1.5e-06    0.0022      12     125 ..     739     849 ..     734     865 .. 0.91
   6 ?    4.8  17.1     0.019        29      11      99 ..     815     900 ..     812     921 .. 0.83
   7 ?   -3.4  12.5       6.7     1e+04      34     104 ..     866     930 ..     848     950 .. 0.48
   8 !    7.8  35.7    0.0024       3.5      12     142 ..     918    1049 ..     906    1050 .. 0.88

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.026
  Tropomyosin_1  24 KeleqenlekeqeiksLtkknqqleeevekleeklkeakekaeesekk..ktnne...........altrkiqlLEeeleesdkkL 96 
                     ele+ +  k +ei +++ k++ +e+ vek  ++l+e+k+++ e++++  + + e           +l+ ki l+E +  + +k+L
     EEA19880.1 338 SELEELKSTKQKEIDDIKSKLESAESAVEKSTTELSEVKRQLTEKSEEidRLKTEaanatsqvntsELNEKISLIEKDKADKEKRL 423
                    478999999******************************98877654311333334578889999999999999999988888876 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.035
  Tropomyosin_1   3 nsLkleaeeaqeka..eeleekvKeleqenlekeqeiksLtkknqqleeevekleeklkeakekaeesekkktn 74 
                      Lk+ea +a  ++  +el+ek+   e+++ +ke+ +  ++  +++l ++v   ee+++  ++ +  ++++  +
     EEA19880.1 387 DRLKTEAANATSQVntSELNEKISLIEKDKADKEKRLGVIEGLVNKLKSQVKDGEETISSLRTDLAGKSNQVGE 460
                    68999*99998876226889999999********9999999999999999999999999888877766666555 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 2.8
  Tropomyosin_1  57 klkeakekaeesekkktnne..altrkiqlLEeeleesdkkLkettekLretdvkaeelERkvk 118
                     +ke+ e+ e ++    +++  al++ki+ L e+l e ++ +     kL+  d   ee+E  + 
     EEA19880.1 545 PIKETPEEPETEAAMIETADvaALEKKIEELTEQLTEKEAAIDRLHAKLKGEDDLKEEIESLRD 608
                    4555555555554444444466777777777777777777777777777777766666665444 PP

  == domain 4  score: 5.3 bits;  conditional E-value: 0.013
  Tropomyosin_1   4 sLkleaeeaqekaeeleekvKeleqenlekeqeiksLtkknqqleeevekleeklkeakekaeesekkktnnea 77 
                     Lk+e ee ++k   le+++ +++q + ++ +++++L++ +q+l  e+ +l ++  e k+++ee +kk ++  +
     EEA19880.1 665 DLKAEFEELKHKSTTLEKDLSAAQQLAASRFKDLTDLKNTMQKLSPELKNLRAESAELKTTKEELNKKVADFKK 738
                    69**************************************************9999999999998888766555 PP

  == domain 5  score: 18.2 bits;  conditional E-value: 1.5e-06
  Tropomyosin_1  12 aqekaeeleekvKeleqenlekeqeiksLtkknqqleeevekleeklkeakekaeesekkktnnealtrkiqlLEeeleesdkkLkettekLretd 107
                      +k+e+l+++vK+l ++  ++e+e+k L++k++q  +   k+ee+l+ +k+ + +se++k+++ + + +      +l +++++Lk+   k+re++
     EEA19880.1 739 LENKHEDLRAEVKSLKSSIADRENEVKTLNQKIRQETDSRLKAEESLSVVKSDLRQSETRKQQAVETQERTS---RDLSRAQEELKNLRAKMREVE 831
                    5789*****************************99999999*********************9999998886...6******************** PP

  Tropomyosin_1 108 vkaeelERkvkaLeqerd 125
                     k+ +l+R+   L +e +
     EEA19880.1 832 EKSTQLDRELSGLREEIQ 849
                    **********99988866 PP

  == domain 6  score: 4.8 bits;  conditional E-value: 0.019
  Tropomyosin_1  11 eaqekaeeleekvKeleqenlekeqeiksLtkknqqleeevekleeklkeakekaeesekkktnnealtrkiqlLEeeleesdkkLket 99 
                     aqe  ++l++k++e e+++++ + e++ L + +q+  ++   +++ ++ ++++ +e +   ++  +   + + LEeel e+ + L+e 
     EEA19880.1 815 RAQEELKNLRAKMREVEEKSTQLDRELSGLREEIQLKTAQHASAQSLMTSMRDQTSEMA---MQMKEARERCESLEEELAEAHRLLTER 900
                    68999999**************************9999998888887777776666554...4455567899********999999874 PP

  == domain 7  score: -3.4 bits;  conditional E-value: 6.7
  Tropomyosin_1  34 eqeiksLtkknqqleeevekleeklkeakekaeesekkktnnealtrkiqlLEeeleesdkkLkettekLr 104
                     ++ +++  +++++ e +e lee+l ea++ + e ++   + e++ r ++ +E   +   +k+++  e+L+
     EEA19880.1 866 RDQTSEMAMQMKEARERCESLEEELAEAHRLLTERSR---EGETMRRLLNEIEGRTD---AKVRDFKERLE 930
                    4445555555566666666666666666555554433...34445444444443333...33333333332 PP

  == domain 8  score: 7.8 bits;  conditional E-value: 0.0024
  Tropomyosin_1   12 aqekaeeleekvKeleqenlekeqeiksLtkknqqleeevekleeklkeakekaeesekkktnne....altrkiqlLEeeleesdkkLkette 101 
                       +k+ + +e++ ++ +e+ + e+e + + ++      e+e+l++k++e++++++++e++k + e      +r+ + LE ++e+s +++ke  +
     EEA19880.1  918 TDAKVRDFKERLEAAIEERDKAEDEANTMGRRRA---RELEELKTKVRETEKALKAAENDKEELEyaqrDWKRRRDDLELQAERSAQEVKEVRQ 1008
                     456999999******9**********99998865...68999999999999999999999988888877999********************** PP

  Tropomyosin_1  102 kLretdvkaeelERkvkaLeqerdewekkyeeleekykeak 142 
                      + +   + +e+ER+v+++e+e+ e  + +ee+++++++ +
     EEA19880.1 1009 AMVQLRDALDESERQVREMEKEKSELRRSIEETNNRLEKLR 1049
                     ************************************99987 PP

>> CENP-F_leu_zip  Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   1.2       6.3   9.4e+03      42     107 ..     113     178 ..      96     181 .. 0.63
   2 ?   -0.6  14.4      0.84   1.3e+03      56     124 ..     191     265 ..     184     269 .. 0.71
   3 !    9.5  11.1   0.00062      0.92       8      72 ..     280     344 ..     274     346 .. 0.83
   4 ?    4.3  23.1     0.025        37       3     113 ..     334     447 ..     332     465 .. 0.89
   5 ?    2.7   2.6     0.076   1.1e+02      51      78 ..     562     589 ..     538     595 .. 0.70
   6 ?   -2.4  22.6       2.9   4.3e+03       5     111 ..     582     685 ..     569     689 .. 0.58
   7 ?    3.4  23.2     0.049        74      22     132 ..     666     786 ..     663     794 .. 0.59
   8 ?    3.7  10.5     0.038        57      35     100 ..     924     993 ..     919     994 .. 0.87
   9 !   17.6  15.8   2.1e-06    0.0031      28     108 ..     977    1057 ..     976    1063 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 6.3
  CENP-F_leu_zip  42 kvileaEtskaevetlkeeieelaeelreleldLvalrsekeeLekelqkkqervseLeslnssle 107
                     + +   E+ k ++ +  e+  el  e r     L+++ s  ++L+k  +    rv   es +s l+
      EEA19880.1 113 EKKEAGEEGKDKATESAEKPPELPIEVRSKLRRLDKIESRYNDLHKAYKMAHARVLLIESFESALR 178
                     444455555555555556666666666666667788888888888888888888887777777665 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.84
  CENP-F_leu_zip  56 tlkeeieelaeelreleldLvalrsekeeLekelqkkq.......ervseLeslnsslenlleekEqekvqmkees 124
                     +l e +++++ +   l  +L+ ++s++++ +k+l +         ++v +L++ + + e+ leekE++k+ + e+ 
      EEA19880.1 191 ALTEYLNQMSLKNDMLMDELKRVTSDRDDFKKKLATAEkatkealDEVATLKEQK-QSEKGLEEKEEKKKTETEKP 265
                     5677788899999999999999999999999998654311111113455555444.57999*****9999888875 PP

  == domain 3  score: 9.5 bits;  conditional E-value: 0.00062
  CENP-F_leu_zip   8 vlekLKeserkadsLkdkvenLerelemseenqekvileaEtskaevetlkeeieelaeelrele 72 
                     ++++ +e +++ ++L   v++L+r+l  + e+ e++++  E+   e+e+l++ +++ ++el+el+
      EEA19880.1 280 LESEVQEKQEEIEKLSTEVDKLKRDLTVARESTESMVITLESTTRELEGLRDFKDKHESELEELK 344
                     67788889999999999999999999999999999999999999999999998888888888876 PP

  == domain 4  score: 4.3 bits;  conditional E-value: 0.025
  CENP-F_leu_zip   3 kkklhvlekLKeserka.dsLkdkvenLerelemseenqekvileaEtskaevetlkeeieelae..elreleldLvalrsekeeLekelqkkqe 94 
                     +k+++ le+LK +++k+ d +k k e+ e+ +e s  ++++v+++  ++ +e+  lk+e  + ++  +++el+ +++ + ++k + ek l     
      EEA19880.1 334 DKHESELEELKSTKQKEiDDIKSKLESAESAVEKSTTELSEVKRQLTEKSEEIDRLKTEAANATSqvNTSELNEKISLIEKDKADKEKRLGVIEG 428
                     6889999****9987655*****************************************9998762256788999******************** PP

  CENP-F_leu_zip  95 rvseLeslnsslenlleek 113
                      v+ L+s   + e++++ +
      EEA19880.1 429 LVNKLKSQVKDGEETISSL 447
                     *******999999998765 PP

  == domain 5  score: 2.7 bits;  conditional E-value: 0.076
  CENP-F_leu_zip  51 kaevetlkeeieelaeelreleldLval 78 
                      a v +l+++ieel+e+l+e e+ ++ l
      EEA19880.1 562 TADVAALEKKIEELTEQLTEKEAAIDRL 589
                     3455568888888888888888777665 PP

  == domain 6  score: -2.4 bits;  conditional E-value: 2.9
  CENP-F_leu_zip   5 klhvlekLKeserkadsLkdkvenLerelemseenqekvileaEtskaevetlkeeieelaeelreleldLvalrsekeeLekelqkkqervseL 99 
                     k+ + ++L +  + +d Lk+ +e+L  el +++++  +++ ++ t   e  +l+e   ++++e  el+++ ++ + + ++L+ +l+    + +eL
      EEA19880.1 582 KEAAIDRLHAKLKGEDDLKEEIESLRDELLNIGQEHVEAKDQVKTLLVEKAALEEARAKIEKEVVELRMNHASASADSDKLHTDLKA---EFEEL 673
                     333444455555556666666666666666666666666666666666666666666666666666666666666788888777765...45666 PP

  CENP-F_leu_zip 100 eslnsslenlle 111
                     +    +le+ l+
      EEA19880.1 674 KHKSTTLEKDLS 685
                     666666666665 PP

  == domain 7  score: 3.4 bits;  conditional E-value: 0.049
  CENP-F_leu_zip  22 LkdkvenLerelemseenqekvileaEtskaevetlkeeieelaeelreleldLvalrsekeeLekel..........qkkqervseLeslnssl 106
                     Lk   e+L+    ++e++++++   a +  + +  lk+ +++l+ el++l+++ ++l+  keeL+k++          ++ + +v++L+s+  + 
      EEA19880.1 666 LKAEFEELKHKSTTLEKDLSAAQQLAASRFKDLTDLKNTMQKLSPELKNLRAESAELKTTKEELNKKVadfkklenkhEDLRAEVKSLKSSIADR 760
                     55556666667777777777777666666677777777777777777777777777777777777654221000000044455666666666666 PP

  CENP-F_leu_zip 107 enlleekEqekvqmkeeskaaveeLq 132
                     en ++ + q+ +q+ ++  +a e+L+
      EEA19880.1 761 ENEVKTLNQKIRQETDSRLKAEESLS 786
                     66666666666666666656656555 PP

  == domain 8  score: 3.7 bits;  conditional E-value: 0.038
  CENP-F_leu_zip  35 mseenqekvileaEtskaevetl....keeieelaeelreleldLvalrsekeeLekelqkkqervseLe 100
                     + +e +e++i e +++  e++t+      e+eel+++ re e  L+a  ++keeLe   +++++r ++Le
      EEA19880.1 924 DFKERLEAAIEERDKAEDEANTMgrrrARELEELKTKVRETEKALKAAENDKEELEYAQRDWKRRRDDLE 993
                     5678999999999999999999733335799**************************9999999999998 PP

  == domain 9  score: 17.6 bits;  conditional E-value: 2.1e-06
  CENP-F_leu_zip   28 nLerelemseenqekvileaEtskaevetlkeeieelaeelreleldLvalrsekeeLekelqkkqervseLeslnsslen 108 
                      +Le    + ++ +++++l+aE s +ev+++++ + +l+  l e e ++ ++ +ek eL +++++ ++r + L ++n  l+ 
      EEA19880.1  977 ELEYAQRDWKRRRDDLELQAERSAQEVKEVRQAMVQLRDALDESERQVREMEKEKSELRRSIEETNNRLEKLRKANKALTD 1057
                      56777777888999************************************************************9988775 PP

>> DUF4763  Domain of unknown function (DUF4763)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0  11.7       1.2   1.8e+03      15     152 ..     338     473 ..     311     484 .. 0.68
   2 ?   -2.5  20.4       1.6   2.5e+03      11     164 ..     584     732 ..     528     734 .. 0.82
   3 ?    2.8   4.3     0.041        61      89     150 ..     723     784 ..     716     790 .. 0.81
   4 ?   -3.3  23.4         3   4.4e+03      18     155 ..     790     915 ..     777     916 .. 0.70
   5 !   16.4  12.6   2.9e-06    0.0043      56     154 ..     952    1055 ..     919    1063 .. 0.78

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.2
     DUF4763  15 q...klsqvsqseqldveeeisseselpaeqeeeeeel..dLdeiydelekiKqrvlelrskLalnvpecPeidecvdedlelelltseqpeileLqrn 108
                 +   +l++ +q+e  d++++++s +++ ++  +e +e+  +L+e  +e++++K+ +    s++ ++       +  ++ +l +++  +++  +  +   
  EEA19880.1 338 SeleELKSTKQKEIDDIKSKLESAESAVEKSTTELSEVkrQLTEKSEEIDRLKTEAANATSQVNTS-------ELNEKISLIEKDKADKEKRLGVIEGL 429
                 144566777788888888888888877654445555544478888888888888888888777776.......77777777777777777777777777 PP

     DUF4763 109 nhkLrqqlaelqqhlkasrkslkelreslcqekkrlrklqkrln 152
                   kL+ q+++ ++   + r++l    +++ ++ k ++     l+
  EEA19880.1 430 VNKLKSQVKDGEETISSLRTDLAGKSNQVGELEKIVKFVDDGLG 473
                 77777777777777777777777777777666666655555555 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 1.6
     DUF4763  11 leveqklsqvsqseqldveeeisseselpaeqeeeeeeldLdeiydelekiKqrvlelrskLalnvpecPeidecvdedlelelltseqpeileLqrnn 109
                 +++     + + ++  d++eei+s  ++    +  +e ++ ++  + l   K+ ++e r k+  +v e      +++ d ++   +  + e  eL++++
  EEA19880.1 584 AAIDRLHAKLKGED--DLKEEIESLRDELL--NIGQEHVEAKDQVKTLLVEKAALEEARAKIEKEVVELRMNHASASADSDKLHTD-LKAEFEELKHKS 677
                 44444555555555..77778877776655..357888888888888888899999999999999988887777777776666555.899999****** PP

     DUF4763 110 hkLrqqlaelqqhlkasrkslkelreslcqekkrlrklqkrlneldsfkrklehe 164
                   L   l+ +qq   +  k+l++l++ ++++   l++l+++  el+  k++l ++
  EEA19880.1 678 TTLEKDLSAAQQLAASRFKDLTDLKNTMQKLSPELKNLRAESAELKTTKEELNKK 732
                 *********999999999*********************9999999999988775 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.041
     DUF4763  89 dlelelltseqpeileLqrnnhkLrqqlaelqqhlkasrkslkelreslcqekkrlrklqkr 150
                 ++ +e+l+++  + ++L  ++  Lr ++++l+++    ++++k l+++++qe+    k +++
  EEA19880.1 723 KTTKEELNKKVADFKKLENKHEDLRAEVKSLKSSIADRENEVKTLNQKIRQETDSRLKAEES 784
                 455556666899999************************************98876666655 PP

  == domain 4  score: -3.3 bits;  conditional E-value: 3
     DUF4763  18 sqvsqseqldveeeisseselpaeqe...eeeeeldLdeiydelekiKqrvlelrskLalnvpecPeidecvdedlelelltseqpeileLqrnnhkLr 113
                 s+ +qse             + ++q+   +e  + dL+ +++el+ +++++ e+++k     +e       ++ +l++ ++ s q     ++ +++ + 
  EEA19880.1 790 SDLRQSE-------------TRKQQAvetQERTSRDLSRAQEELKNLRAKMREVEEKSTQLDRELS--GLREEIQLKTAQHASAQSLMTSMRDQTSEMA 873
                 3333333.............2233322012233345555555555555555555555332222222..788999999999999999************* PP

     DUF4763 114 qqlaelqqhlkasrkslkelreslcqekkrlrklqkrlneld 155
                  q++e+ +++++ +++l e ++ l +  + ++ +++ lne++
  EEA19880.1 874 MQMKEARERCESLEEELAEAHRLLTERSREGETMRRLLNEIE 915
                 ***************************************975 PP

  == domain 5  score: 16.4 bits;  conditional E-value: 2.9e-06
     DUF4763   56 delekiKqrvlelrskLalnvpecPei......decvdedlelelltseqpeileLqrnnhkLrqqlaelqqhlkasrkslkelreslcqekkrlrk 146 
                   ele++K++v e ++ L+    ++ e+       +   +dlel++ +   +e++e++++ ++Lr  l+e +++ ++++k+ +elr+s+ + ++rl+k
  EEA19880.1  952 RELEELKTKVRETEKALKAAENDKEELeyaqrdWKRRRDDLELQAER-SAQEVKEVRQAMVQLRDALDESERQVREMEKEKSELRRSIEETNNRLEK 1047
                  46777777777777777777666665544443345566777777777.899********************************************** PP

     DUF4763  147 lqkrlnel 154 
                  l+k  ++l
  EEA19880.1 1048 LRKANKAL 1055
                  *9987765 PP

>> Seryl_tRNA_N  Seryl-tRNA synthetase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.7       2.3   3.4e+03      50      91 ..     102     129 ..      92     163 .. 0.48
   2 ?   -1.0  10.7       1.4     2e+03      11      83 ..     189     262 ..     176     269 .. 0.58
   3 ?    5.1   8.8     0.017        25      17      98 ..     254     341 ..     249     343 .. 0.78
   4 ?    1.9  10.7      0.17   2.6e+02      30     101 ..     325     397 ..     318     402 .. 0.70
   5 ?    1.4   3.7      0.25   3.8e+02      45     100 ..     398     454 ..     389     461 .. 0.74
   6 ?   -1.6  10.1       2.1   3.1e+03      66     103 ..     553     592 ..     486     596 .. 0.73
   7 ?    4.9   6.8      0.02        30      40     101 ..     567     628 ..     563     630 .. 0.92
   8 ?    1.8   9.9      0.18   2.7e+02      29      94 ..     615     688 ..     597     700 .. 0.66
   9 !   16.3  11.9   5.7e-06    0.0085      30      99 ..     704     773 ..     689     777 .. 0.87
  10 ?    3.9  12.0     0.042        63      13      99 ..     802     892 ..     791     899 .. 0.78
  11 ?    0.4   5.6      0.49   7.3e+02      32      98 ..     870     944 ..     865     949 .. 0.65
  12 ?   -1.5   9.7       1.9   2.9e+03      35      97 ..     919     982 ..     916     988 .. 0.87
  13 ?   -1.5  13.0       1.9   2.9e+03      11      98 ..     978    1060 ..     975    1063 .. 0.75

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 2.3
                   HHHHHHHHHCCCCCCTTS-TCCCCCCCHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N  50 aerNelskeIgkakkkkedaeeliaevkelkeelkaleaelk 91 
                   +e  e+  + g++k+++              ee k++ +e +
    EEA19880.1 102 NEGAEAEGKDGEKKEAG--------------EEGKDKATESA 129
                   33333333334444444..............33333322222 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 1.4
                   HHHHHHHHCCCT.CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTTS-TCCCCCCCHHHHHHH CS
  Seryl_tRNA_N  11 peavkeklkkRg.edkadvdelleldekrrelqveleelqaerNelskeIgkakkkkedaeeliaevkelkeel 83 
                   p+a+ e l++   + + ++del  + + r   +++l  + +  +e+  e++ +k++k+  + l ++ ++ k+e+
    EEA19880.1 189 PKALTEYLNQMSlKNDMLMDELKRVTSDRDDFKKKLATAEKATKEALDEVATLKEQKQSEKGLEEKEEKKKTET 262
                   55555555544445556667777777777777777777777777777777777766633333333333333333 PP

  == domain 3  score: 5.1 bits;  conditional E-value: 0.017
                   HHCCCT..CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTT....S-TCCCCCCCHHHHHHHHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N  17 klkkRg..edkadvdelleldekrrelqveleelqaerNelskeIgkakkkk....edaeeliaevkelkeelkaleaelkeleaele 98 
                   k +k++   +k + +++++ d++  +l++e++e q+e  +ls e+ k+k++     e +e+++   ++   el+ l +  ++ e+ele
    EEA19880.1 254 KEEKKKteTEKPESEDFFSFDNEIPRLESEVQEKQEEIEKLSTEVDKLKRDLtvarESTESMVITLESTTRELEGLRDFKDKHESELE 341
                   44444445788999************************************98777677777777777777777777666666666665 PP

  == domain 4  score: 1.9 bits;  conditional E-value: 0.17
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTT.S-TCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N  30 elleldekrrelqveleelqaerNelskeIgkakkkk.edaeeliaevkelkeelkaleaelkeleaelekll 101
                   el  l + + ++++eleel++ + +    I+++ ++     e+   e +e+k +l ++++e + l++e  +++
    EEA19880.1 325 ELEGLRDFKDKHESELEELKSTKQKEIDDIKSKLESAeSAVEKSTTELSEVKRQLTEKSEEIDRLKTEAANAT 397
                   4555555566778888888888887777777777777556666777888888888888888888887776665 PP

  == domain 5  score: 1.4 bits;  conditional E-value: 0.25
                   HHHHHHHHHHHHHHCCCCCCTTS-TCCCCC.CCHHHHHHHHHHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N  45 leelqaerNelskeIgkakkkkedaeelia.evkelkeelkaleaelkeleaelekl 100
                    +   +e Ne    I+k k++ke++  +i+  v++lk ++k+ e++ + l+++l  +
    EEA19880.1 398 SQVNTSELNEKISLIEKDKADKEKRLGVIEgLVNKLKSQVKDGEETISSLRTDLAGK 454
                   4445567777778888888888777777763589************99999988765 PP

  == domain 6  score: -1.6 bits;  conditional E-value: 2.1
                   T..S-TCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCT CS
  Seryl_tRNA_N  66 k..edaeeliaevkelkeelkaleaelkeleaelekllla 103
                      e a    a+v++l +++++l+++l+e ea+++ l ++
    EEA19880.1 553 PetEAAMIETADVAALEKKIEELTEQLTEKEAAIDRLHAK 592
                   2444555555667777777777777777777777776554 PP

  == domain 7  score: 4.9 bits;  conditional E-value: 0.02
                   HHHHHHHHHHHHHHHHHHHCCCCCCTTS-TCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N  40 elqveleelqaerNelskeIgkakkkkedaeeliaevkelkeelkaleaelkeleaelekll 101
                   +l++++eel ++  e  ++I ++ +k +  ++l++e+++l +el ++ +e  e+++++++ll
    EEA19880.1 567 ALEKKIEELTEQLTEKEAAIDRLHAKLKGEDDLKEEIESLRDELLNIGQEHVEAKDQVKTLL 628
                   688999******************999999***************************99987 PP

  == domain 8  score: 1.8 bits;  conditional E-value: 0.18
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTT........S-TCCCCCCCHHHHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N  29 delleldekrrelqveleelqaerNelskeIgkakkkk........edaeeliaevkelkeelkaleaelkele 94 
                   +e +e+ ++ ++l ve  +l + r ++ ke+ ++  ++        +  ++l+ae +elk +  +le++l++++
    EEA19880.1 615 QEHVEAKDQVKTLLVEKAALEEARAKIEKEVVELRMNHasasadsdKLHTDLKAEFEELKHKSTTLEKDLSAAQ 688
                   45667777888888888888888888888888777777443333333444556666666666666666665554 PP

  == domain 9  score: 16.3 bits;  conditional E-value: 5.7e-06
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTTS-TCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N  30 elleldekrrelqveleelqaerNelskeIgkakkkkedaeeliaevkelkeelkaleaelkeleaelek 99 
                   ++ +l  + ++l++e  el++ + el+k+++  kk +++ e+l+aevk+lk  +++ e+e+k+l++++ +
    EEA19880.1 704 TMQKLSPELKNLRAESAELKTTKEELNKKVADFKKLENKHEDLRAEVKSLKSSIADRENEVKTLNQKIRQ 773
                   456788999********************************************************99876 PP

  == domain 10  score: 3.9 bits;  conditional E-value: 0.042
                   HHHHHHCCCTCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTTS-TCCCCCCCH....HHHHHHHHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N  13 avkeklkkRgedkadvdelleldekrrelqveleelqaerNelskeIgkakkkkedaeeliaevk....elkeelkaleaelkeleaelek 99 
                   av+ + ++ ++ +   +el  l +k+re++ +  +l +e   l +eI+ + ++++ a++l+ +++    e+  ++k++ ++ + le+el +
    EEA19880.1 802 AVETQERTSRDLSRAQEELKNLRAKMREVEEKSTQLDRELSGLREEIQLKTAQHASAQSLMTSMRdqtsEMAMQMKEARERCESLEEELAE 892
                   555555555577888899************************************9999998877611115566667777777777777765 PP

  == domain 11  score: 0.4 bits;  conditional E-value: 0.49
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTT........S-TCCCCCCCHHHHHHHHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N  32 leldekrrelqveleelqaerNelskeIgkakkkk........edaeeliaevkelkeelkaleaelkeleaele 98 
                    e+  +++e++ + e+l +e  e+ +   + ++++        e   +  a+v++ ke+l+a+ +e +++e+e +
    EEA19880.1 870 SEMAMQMKEARERCESLEEELAEAHRLLTERSREGetmrrllnEIEGRTDAKVRDFKERLEAAIEERDKAEDEAN 944
                   566666777777777777777777777777777774444444334445667788888888888888888887766 PP

  == domain 12  score: -1.5 bits;  conditional E-value: 1.9
                   HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTT.S-TCCCCCCCHHHHHHHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N  35 dekrrelqveleelqaerNelskeIgkakkkk.edaeeliaevkelkeelkaleaelkeleael 97 
                   d+k r  + +le++ +er ++  e   + ++   + eel+ +v+e  + lka+e++ +ele ++
    EEA19880.1 919 DAKVRDFKERLEAAIEERDKAEDEANTMGRRRaRELEELKTKVRETEKALKAAENDKEELEYAQ 982
                   89999999999999999999999988888877899999***************99999998665 PP

  == domain 13  score: -1.5 bits;  conditional E-value: 1.9
                    HHHHHHHHCCCTCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTTS-TCCCCCCCHHHHHHHHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N   11 peavkeklkkRgedkadvdelleldekrrelqveleelqaerNelskeIgkakkkkedaeeliaevkelkeelkaleaelkeleaele 98  
                    +e  ++ +k+R+ d++++++     ++ +e+++++ +l+    e  +++ ++ k+k   +el+ +++e +++l++l ++ k+l++e+ 
    EEA19880.1  978 LEYAQRDWKRRR-DDLELQA-ERSAQEVKEVRQAMVQLRDALDESERQVREMEKEK---SELRRSIEETNNRLEKLRKANKALTDEFS 1060
                    566666776664.5555544.44557889999999999999999999999999866...88888889999999999998888888865 PP

>> Cep57_CLD_2  Centrosome localisation domain of PPC89
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   6.7   9.8e-05      0.15       6      66 ..     190     256 ..     189     257 .. 0.92
   2 ?   15.7   1.7   7.7e-06     0.011      10      66 ..     275     331 ..     273     332 .. 0.94
   3 ?    5.9   7.9    0.0091        14       1      54 [.     340     393 ..     337     410 .. 0.89
   4 ?   -3.0   0.0       5.4     8e+03       2      20 ..     441     459 ..     441     463 .. 0.73
   5 ?    2.3  10.2      0.12   1.8e+02      20      61 ..     566     610 ..     562     640 .. 0.85
   6 ?    1.1   1.2      0.29   4.4e+02      41      65 ..     653     677 ..     621     679 .. 0.81
   7 ?   -3.8   8.9       9.8   1.5e+04       7      66 ..     679     717 ..     660     744 .. 0.61
   8 ?    0.3   4.1       0.5   7.4e+02       1      35 [.     739     777 ..     739     794 .. 0.81
   9 ?   -0.7   3.7         1   1.6e+03      35      59 ..     808     832 ..     782     838 .. 0.77
  10 ?    9.0   6.8     0.001       1.5       1      55 [.     837     891 ..     837     902 .. 0.94
  11 ?   -2.2   8.5         3   4.5e+03       3      63 ..     920     980 ..     918     985 .. 0.88
  12 ?    1.6   9.0       0.2     3e+02       5      48 ..    1010    1053 ..    1006    1062 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 9.8e-05
  Cep57_CLD_2   6 ktLqnrLdsltrklqvheeelkrLnkERdsalrqLgvAyeelneLkaevealrkE......Lkeqra 66 
                  k+L + L++++ k+ +  +elkr+ ++Rd + ++L  A   + e  +ev +l+++      L+e+++
   EEA19880.1 190 KALTEYLNQMSLKNDMLMDELKRVTSDRDDFKKKLATAEKATKEALDEVATLKEQkqsekgLEEKEE 256
                  689999************************************************9888777777765 PP

  == domain 2  score: 15.7 bits;  conditional E-value: 7.7e-06
  Cep57_CLD_2  10 nrLdsltrklqvheeelkrLnkERdsalrqLgvAyeelneLkaevealrkELkeqra 66 
                  n+  +l++++q+ +ee+++L++E d   r L vA+e +++    +e+  +EL+  r+
   EEA19880.1 275 NEIPRLESEVQEKQEEIEKLSTEVDKLKRDLTVARESTESMVITLESTTRELEGLRD 331
                  666799**********************************************98875 PP

  == domain 3  score: 5.9 bits;  conditional E-value: 0.0091
  Cep57_CLD_2   1 LeaevktLqnrLdsltrklqvheeelkrLnkERdsalrqLgvAyeelneLkaev 54 
                  Le  ++t q + d + +kl+++e++ ++  +E +++ rqL ++ ee++ Lk e 
   EEA19880.1 340 LEELKSTKQKEIDDIKSKLESAESAVEKSTTELSEVKRQLTEKSEEIDRLKTEA 393
                  55666666999****************************************995 PP

  == domain 4  score: -3.0 bits;  conditional E-value: 5.4
  Cep57_CLD_2   2 eaevktLqnrLdsltrklq 20 
                  e ++++L+++L   + +++
   EEA19880.1 441 EETISSLRTDLAGKSNQVG 459
                  678999**99976666555 PP

  == domain 5  score: 2.3 bits;  conditional E-value: 0.12
  Cep57_CLD_2  20 qvheeelkrLnk...ERdsalrqLgvAyeelneLkaevealrkEL 61 
                  ++ e  +++L     E + a+ +L+ ++   ++Lk+e e+lr EL
   EEA19880.1 566 AALEKKIEELTEqltEKEAAIDRLHAKLKGEDDLKEEIESLRDEL 610
                  566666677766667*****************************5 PP

  == domain 6  score: 1.1 bits;  conditional E-value: 0.29
  Cep57_CLD_2  41 gvAyeelneLkaevealrkELkeqr 65 
                   +A  ++++L+  + a  +ELk++ 
   EEA19880.1 653 ASASADSDKLHTDLKAEFEELKHKS 677
                  5788999999999999999999985 PP

  == domain 7  score: -3.8 bits;  conditional E-value: 9.8
  Cep57_CLD_2   7 tLqnrLdsltrklqvheeelkrLnkERd.salrqLgv.AyeelneLkaevealrkELkeqra 66 
                  tL                       E d sa++qL    + +l +Lk+    l  ELk  ra
   EEA19880.1 679 TL-----------------------EKDlSAAQQLAAsRFKDLTDLKNTMQKLSPELKNLRA 717
                  23.......................5552345555554666666666666666666665554 PP

  == domain 8  score: 0.3 bits;  conditional E-value: 0.5
  Cep57_CLD_2   1 LeaevktLqnrLdsltrklqvheeelkrLnk....ERds 35 
                  Le   + L+ + +sl + ++  e e k+Ln+    E ds
   EEA19880.1 739 LENKHEDLRAEVKSLKSSIADRENEVKTLNQkirqETDS 777
                  56667789999************9999999866666665 PP

  == domain 9  score: -0.7 bits;  conditional E-value: 1
  Cep57_CLD_2  35 salrqLgvAyeelneLkaevealrk 59 
                  +  r L++A eel +L+a+ +  ++
   EEA19880.1 808 RTSRDLSRAQEELKNLRAKMREVEE 832
                  5567788888888888887766554 PP

  == domain 10  score: 9.0 bits;  conditional E-value: 0.001
  Cep57_CLD_2   1 LeaevktLqnrLdsltrklqvheeelkrLnkERdsalrqLgvAyeelneLkaeve 55 
                  L++e + L+++    t + +++++++ +++   +++++q  +A+e++++L +e+ 
   EEA19880.1 837 LDRELSGLREEIQLKTAQHASAQSLMTSMRDQTSEMAMQMKEARERCESLEEELA 891
                  7899999*********************************************985 PP

  == domain 11  score: -2.2 bits;  conditional E-value: 3
  Cep57_CLD_2   3 aevktLqnrLdsltrklqvheeelkrLnkERdsalrqLgvAyeelneLkaevealrkELke 63 
                  a v   ++rL+ + ++  ++e+e +++ + R + l  L  + +e+++     e +++EL++
   EEA19880.1 920 AKVRDFKERLEAAIEERDKAEDEANTMGRRRARELEELKTKVRETEKALKAAENDKEELEY 980
                  56666789999999999****************************9999999999999985 PP

  == domain 12  score: 1.6 bits;  conditional E-value: 0.2
  Cep57_CLD_2    5 vktLqnrLdsltrklqvheeelkrLnk...ERdsalrqLgvAyeeln 48  
                     +L++ Ld  +r++ + e e+ +L++   E ++ l +L+ A   + 
   EEA19880.1 1010 MVQLRDALDESERQVREMEKEKSELRRsieETNNRLEKLRKA---NK 1053
                   568************************666666666666655...44 PP

>> DivIC  Septum formation initiator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   3.0       2.4   3.6e+03      45      55 ..     208     218 ..     190     256 .. 0.53
   2 ?   -2.5   2.2         3   4.5e+03      17      42 ..     239     264 ..     221     270 .. 0.66
   3 ?   14.8   0.9   1.2e-05     0.018      18      53 ..     269     304 ..     264     311 .. 0.87
   4 ?    0.6   0.7      0.32   4.8e+02      14      53 ..     321     346 ..     314     369 .. 0.51
   5 ?    4.2   2.8     0.024        36      13      48 ..     366     401 ..     358     414 .. 0.80
   6 ?    0.5   0.3      0.35   5.3e+02      16      52 ..     399     435 ..     396     469 .. 0.73
   7 ?    3.2   1.9     0.049        74      25      51 ..     564     590 ..     560     598 .. 0.70
   8 ?    3.8   4.3     0.034        50      21      63 ..     598     639 ..     593     643 .. 0.87
   9 ?   -0.7   0.2      0.82   1.2e+03      28      46 ..     665     683 ..     641     697 .. 0.66
  10 ?    6.7   1.4     0.004         6      17      50 ..     703     736 ..     694     738 .. 0.80
  11 ?    4.9   6.9     0.015        22      22      52 ..     725     755 ..     721     784 .. 0.71
  12 ?    1.5   3.0      0.17   2.5e+02      16      51 ..     810     845 ..     794     851 .. 0.74
  13 ?    1.9   0.6      0.13   1.9e+02      12      50 ..     855     893 ..     848     910 .. 0.81
  14 ?   -2.1   0.1       2.2   3.3e+03      23      50 ..     919     946 ..     917     955 .. 0.75
  15 ?   -2.0   8.9         2     3e+03      14      61 ..     949     996 ..     943    1005 .. 0.87
  16 ?    1.2   3.2      0.22   3.2e+02      15      50 ..     999    1034 ..     994    1037 .. 0.56
  17 ?    6.0   1.6    0.0069        10      20      49 ..    1032    1061 ..    1029    1066 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 2.4
                 HHHCC-XXXXX CS
       DivIC  45 aevkdLksded 55 
                 +e+k+ +sd+d
  EEA19880.1 208 DELKRVTSDRD 218
                 44444444332 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 3
                 XHHHHHHHHHHHHHHHHHHHHHHHHH CS
       DivIC  17 laykqlkqeiaalqaelaklkaenee 42 
                  ++k++kq  + l+++ +k+k e e+
  EEA19880.1 239 ATLKEQKQSEKGLEEKEEKKKTETEK 264
                 45556666666666666666666655 PP

  == domain 3  score: 14.8 bits;  conditional E-value: 1.2e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC-XXX CS
       DivIC  18 aykqlkqeiaalqaelaklkaeneeLeaevkdLksd 53 
                 ++++ ++ei +l+ e++++++e+e+L  ev++Lk d
  EEA19880.1 269 DFFSFDNEIPRLESEVQEKQEEIEKLSTEVDKLKRD 304
                 567899***************************754 PP

  == domain 4  score: 0.6 bits;  conditional E-value: 0.32
                 XXXXHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC-XXX CS
       DivIC  14 kgllaykqlkqeiaalqaelaklkaeneeLeaevkdLksd 53 
                 ++              ++el+ l++ +++ e+e+++Lks+
  EEA19880.1 321 ST--------------TRELEGLRDFKDKHESELEELKST 346
                 44..............444555555555555555555432 PP

  == domain 5  score: 4.2 bits;  conditional E-value: 0.024
                 XXXXXHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
       DivIC  13 kkgllaykqlkqeiaalqaelaklkaeneeLeaevk 48 
                 +k+   ++++k++++++ +e+++lk e ++ +++v+
  EEA19880.1 366 EKSTTELSEVKRQLTEKSEEIDRLKTEAANATSQVN 401
                 566777888888888888888888888888888776 PP

  == domain 6  score: 0.5 bits;  conditional E-value: 0.35
                 XXHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC-XX CS
       DivIC  16 llaykqlkqeiaalqaelaklkaeneeLeaevkdLks 52 
                 +++ ++l+++i  ++++ a + ++    e  v++Lks
  EEA19880.1 399 QVNTSELNEKISLIEKDKADKEKRLGVIEGLVNKLKS 435
                 6677778888888888877777777777777777765 PP

  == domain 7  score: 3.2 bits;  conditional E-value: 0.049
                 HHHHHHHHHHHHHHHHHHHHHHHCC-X CS
       DivIC  25 eiaalqaelaklkaeneeLeaevkdLk 51 
                 ++aal++++++l+++  e ea +++L+
  EEA19880.1 564 DVAALEKKIEELTEQLTEKEAAIDRLH 590
                 677777777777777777777777774 PP

  == domain 8  score: 3.8 bits;  conditional E-value: 0.034
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHCC-XXXXXXXXXXXXX CS
       DivIC  21 qlkqeiaalqaelaklkaeneeLeaevkdLksdedyieerARs 63 
                 +lk+ei+ l +el ++ +e  e +++vk L   e +  e AR 
  EEA19880.1 598 DLKEEIESLRDELLNIGQEHVEAKDQVKTLL-VEKAALEEARA 639
                 699***************************5.66666666776 PP

  == domain 9  score: -0.7 bits;  conditional E-value: 0.82
                 HHHHHHHHHHHHHHHHHHH CS
       DivIC  28 alqaelaklkaeneeLeae 46 
                 +l+ae ++lk +   Le+ 
  EEA19880.1 665 DLKAEFEELKHKSTTLEKD 683
                 4444444444444444443 PP

  == domain 10  score: 6.7 bits;  conditional E-value: 0.004
                 XHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC- CS
       DivIC  17 laykqlkqeiaalqaelaklkaeneeLeaevkdL 50 
                 +++++l  e++ l ae a+lk ++eeL+++v+d 
  EEA19880.1 703 NTMQKLSPELKNLRAESAELKTTKEELNKKVADF 736
                 5778888888888888888888888888888876 PP

  == domain 11  score: 4.9 bits;  conditional E-value: 0.015
                 HHHHHHHHHHHHHHHHHHHHHHHHHHCC-XX CS
       DivIC  22 lkqeiaalqaelaklkaeneeLeaevkdLks 52 
                 +k+e++++ a+ +kl ++ e+L aevk Lks
  EEA19880.1 725 TKEELNKKVADFKKLENKHEDLRAEVKSLKS 755
                 6677777777777777777777777777764 PP

  == domain 12  score: 1.5 bits;  conditional E-value: 0.17
                 XXHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC-X CS
       DivIC  16 llaykqlkqeiaalqaelaklkaeneeLeaevkdLk 51 
                  +++++ ++e++ l a++ ++ ++  +L++e++ L+
  EEA19880.1 810 SRDLSRAQEELKNLRAKMREVEEKSTQLDRELSGLR 845
                 456677777777777777777777777777777664 PP

  == domain 13  score: 1.9 bits;  conditional E-value: 0.13
                 XXXXXXHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC- CS
       DivIC  12 gkkgllaykqlkqeiaalqaelaklkaeneeLeaevkdL 50 
                 +++ ++ + +++ +  +   ++++ +++ e+Le+e+++ 
  EEA19880.1 855 HASAQSLMTSMRDQTSEMAMQMKEARERCESLEEELAEA 893
                 5566666789999**********************9876 PP

  == domain 14  score: -2.1 bits;  conditional E-value: 2.2
                 HHHHHHHHHHHHHHHHHHHHHHHHHCC- CS
       DivIC  23 kqeiaalqaelaklkaeneeLeaevkdL 50 
                 ++++ + ++ l++  +e+++ e+e + +
  EEA19880.1 919 DAKVRDFKERLEAAIEERDKAEDEANTM 946
                 5677777888888888888888887765 PP

  == domain 15  score: -2.0 bits;  conditional E-value: 2
                 XXXXHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC-XXXXXXXXXXX CS
       DivIC  14 kgllaykqlkqeiaalqaelaklkaeneeLeaevkdLksdedyieerA 61 
                 +  + + +lk ++ + ++ l++  +++eeLe   +d+k  +d +e +A
  EEA19880.1 949 RRARELEELKTKVRETEKALKAAENDKEELEYAQRDWKRRRDDLELQA 996
                 5567789999***************************99998888777 PP

  == domain 16  score: 1.2 bits;  conditional E-value: 0.22
                  XXXHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC- CS
       DivIC   15 gllaykqlkqeiaalqaelaklkaeneeLeaevkdL 50  
                  + + +k+++q +++l + l++   + +e+e+e ++L
  EEA19880.1  999 SAQEVKEVRQAMVQLRDALDESERQVREMEKEKSEL 1034
                  445555566666666666666666666666655555 PP

  == domain 17  score: 6.0 bits;  conditional E-value: 0.0069
                  HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC CS
       DivIC   20 kqlkqeiaalqaelaklkaeneeLeaevkd 49  
                  ++l++ i++ ++ l+kl++ n++L++e ++
  EEA19880.1 1032 SELRRSIEETNNRLEKLRKANKALTDEFSR 1061
                  6899*********************99765 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   9.3    0.0038       5.7      24     127 ..     204     307 ..     202     314 .. 0.85
   2 ?   14.5   5.0   2.1e-05     0.031      26     129 ..     340     448 ..     328     501 .. 0.84
   3 ?    4.2   0.9     0.031        46      65     124 ..     532     592 ..     518     596 .. 0.81
   4 ?    2.5   7.2       0.1   1.5e+02      31     121 ..     597     715 ..     593     728 .. 0.46
   5 ?   10.0  10.3   0.00049      0.73      24     129 ..     664     775 ..     654     777 .. 0.77
   6 ?   10.7  15.4    0.0003      0.44      31     130 ..     737     839 ..     726     843 .. 0.91
   7 ?    3.7   4.7     0.044        65      30     122 ..     834     926 ..     832     938 .. 0.81
   8 ?    1.1  11.0      0.27   4.1e+02      52     130 ..     955    1036 ..     906    1044 .. 0.76

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0038
                 HCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  24 dlllkyekdvkkdlekleneleeisnstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvLqnvlesneqkiqkLe 122
                 d+l +  k v+ d ++ +++l+++++ tkea + v ++k++ ++++  ++++++  ++ +k   e+   ++++i + es++++ q+ +e+++ ++ kL+
  EEA19880.1 204 DMLMDELKRVTSDRDDFKKKLATAEKATKEALDEVATLKEQKQSEKGLEEKEEKKKTETEKPESEDFFSFDNEIPRLESEVQEKQEEIEKLSTEVDKLK 302
                 67777888999999**************************99988888877755555555555559********************************9 PP

                 HHHHH CS
   Fib_alpha 123 qdidq 127
                  d + 
  EEA19880.1 303 RDLTV 307
                 98765 PP

  == domain 2  score: 14.5 bits;  conditional E-value: 2.1e-05
                 CCCCCCCCCHHHCCCCCCCCCCC....CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  26 llkyekdvkkdlekleneleeis....nstkeaeelvkeikdslrekqkskkdndnvikks.skeleeeilrlketidaqesnirvLqnvlesneqkiq 119
                 l++ +++ +k++++++++le+++    +st+e +e+ ++++++ +e  + k++  n+++++ ++el+e+i+ +++   ++e+++ v+ +++++++++++
  EEA19880.1 340 LEELKSTKQKEIDDIKSKLESAEsaveKSTTELSEVKRQLTEKSEEIDRLKTEAANATSQVnTSELNEKISLIEKDKADKEKRLGVIEGLVNKLKSQVK 438
                 66777788899999999999865111156666666666666666666666777788888872589******************************9999 PP

                 HHHHHHHHHH CS
   Fib_alpha 120 kLeqdidqke 129
                 + e+ i++++
  EEA19880.1 439 DGEETISSLR 448
                 9888888765 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.031
                 HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH.HHHCCHHHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  65 lrekqkskkdndnvikksskeleeeilrlke.tidaqesnirvLqnvlesneqkiqkLeqd 124
                  ++k+k k+ ++  ik+  +e e+e + ++   + a e++i++L++ l ++e  i +L  +
  EEA19880.1 532 KNKKKKGKQAEEAPIKETPEEPETEAAMIETaDVAALEKKIEELTEQLTEKEAAIDRLHAK 592
                 45566666667999999999999999999862577778******************99876 PP

  == domain 4  score: 2.5 bits;  conditional E-value: 0.1
                 CCCCHHHCCCCCCCCCCCCHHHHHHHHHHHH...HHHHHHHHHHHHH.........................HHHHHHHHHHHHHHCCCHHHHHHHCCH CS
   Fib_alpha  31 kdvkkdlekleneleeisnstkeaeelvkei...kdslrekqkskkd.........................ndnvikksskeleeeilrlketidaqe 101
                  d+k+++e+l++el +i +++ ea++ vk++   k  l+e+ ++ ++                         + + +k+ s++le++ +  ++   + +
  EEA19880.1 597 DDLKEEIESLRDELLNIGQEHVEAKDQVKTLlveKAALEEARAKIEKevvelrmnhasasadsdklhtdlkaEFEELKHKSTTLEKDLSAAQQLAASRF 695
                 566666666666666666666666666666522222222322222224555555433322222222222211122333444455555555555555555 PP

                 HHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha 102 snirvLqnvlesneqkiqkL 121
                 + +  L+n++++++ ++++L
  EEA19880.1 696 KDLTDLKNTMQKLSPELKNL 715
                 55555555555555555555 PP

  == domain 5  score: 10.0 bits;  conditional E-value: 0.00049
                 HCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH...HHHHHHHHHHHHHCCCHHHHHHHCCH...HHHHHHHHHHHHHHH CS
   Fib_alpha  24 dlllkyekdvkkdlekleneleeisnstkeaeelvkeikdslrekqkskkdn...dnvikksskeleeeilrlketidaqe...snirvLqnvlesneq 116
                 + l+   +++k++ ++le++l+ +++   + ++  +++k+++++   + k+    +  +k  ++el+++++++k+  +++e    +++ L++ + + e+
  EEA19880.1 664 TDLKAEFEELKHKSTTLEKDLSAAQQLAASRFKDLTDLKNTMQKLSPELKNLraeSAELKTTKEELNKKVADFKKLENKHEdlrAEVKSLKSSIADREN 762
                 567777788899999999999999998888877777666666655444443233388899999999999999998888887655689999999999999 PP

                 HHHHHHHHHHHHH CS
   Fib_alpha 117 kiqkLeqdidqke 129
                 +++ L+q+i q +
  EEA19880.1 763 EVKTLNQKIRQET 775
                 9999999999876 PP

  == domain 6  score: 10.7 bits;  conditional E-value: 0.0003
                 CCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHH...HHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  31 kdvkkdlekleneleeisnstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvL...qnvlesneqkiqkLeqdid 126
                 k+++++ e+l+ e++++++s  + e+ vk++++++r++  s  + ++ ++ ++++l++  +r ++ + +qe++ r L   q+ l++++ k+ + e++++
  EEA19880.1 737 KKLENKHEDLRAEVKSLKSSIADRENEVKTLNQKIRQETDSRLKAEESLSVVKSDLRQSETRKQQAVETQERTSRDLsraQEELKNLRAKMREVEEKST 835
                 567788899**********************************99**************************777776555899**************** PP

                 HHHH CS
   Fib_alpha 127 qker 130
                 q+ r
  EEA19880.1 836 QLDR 839
                 9987 PP

  == domain 7  score: 3.7 bits;  conditional E-value: 0.044
                 CCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  30 ekdvkkdlekleneleeisnstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvLqnvlesneqkiqkLe 122
                  ++++++l+ l++e++  + ++ +a++l+++++d++ e   + k+  +  +++++el e +  l e+  + e+  r L ++  + + k+ + +
  EEA19880.1 834 STQLDRELSGLREEIQLKTAQHASAQSLMTSMRDQTSEMAMQMKEARERCESLEEELAEAHRLLTERSREGETMRRLLNEIEGRTDAKVRDFK 926
                 5788999*************************************99999******99988888877776666666666666666666665555 PP

  == domain 8  score: 1.1 bits;  conditional E-value: 0.27
                  HHHHHHHHHHHHHHHHHHHHHHHH...HHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha   52 keaeelvkeikdslrekqkskkdn...dnvikksskeleeeilrlketidaqesnirvLqnvlesneqkiqkLeqdidqker 130 
                  +e ++ v+e+++ l+++++ k++    ++  k+ +++le + +r  +++++  + + +L++ l++ e+++ ++e++ ++++r
  EEA19880.1  955 EELKTKVRETEKALKAAENDKEELeyaQRDWKRRRDDLELQAERSAQEVKEVRQAMVQLRDALDESERQVREMEKEKSELRR 1036
                  3444445555555555554444433337788888999999999999999999999999999999999999999888777665 PP

>> Fez1  Fez1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2  12.4     0.036        54      20     139 ..     122     257 ..     110     276 .. 0.79
   2 ?    3.6  24.3     0.052        77      33     149 ..     238     377 ..     235     379 .. 0.59
   3 ?    3.1  20.9     0.075   1.1e+02      33     136 ..     316     443 ..     314     562 .. 0.67
   4 ?    3.7  18.2      0.05        75      32     144 ..     564     684 ..     557     713 .. 0.48
   5 ?    6.6  14.4    0.0066       9.9      17     109 ..     682     777 ..     677     786 .. 0.76
   6 ?    8.2  25.1    0.0021       3.2      43     150 ..     788     896 ..     778     913 .. 0.81
   7 ?   -3.4  29.3       7.6   1.1e+04      26     155 ..     857     979 ..     849    1009 .. 0.63
   8 ?    9.5   9.7   0.00083       1.2      24     102 ..     996    1072 ..     991    1153 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.036
        Fez1  20 kdsqaevtqklsei.valkaqlrelrakleekeeeikeleesleektlelevcenelqrk...................kseaellrekvekleeelke 98 
                 kd  +e ++k  e+ ++++++lr l  k+e++ + ++++ + ++ + l +e  e+ l+++                   + ++++l ++++++ ++  +
  EEA19880.1 122 KDKATESAEKPPELpIEVRSKLRRLD-KIESRYNDLHKAYKMAHARVLLIESFESALRENtpltsigdpkalteylnqmSLKNDMLMDELKRVTSDRDD 219
                 77788888888887688888888764.67888888888888888999999999999999999999999999999999888899999999********** PP

        Fez1  99 lreelselsleeeeaalesdeakaqrqeaeeleelkrever 139
                 ++++l+++++ ++ea  e  + k+q+q+++ lee ++   +
  EEA19880.1 220 FKKKLATAEKATKEALDEVATLKEQKQSEKGLEEKEE---K 257
                 *******999999999999999999988544443332...2 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.052
        Fez1  33 ivalkaqlrelrakleekeeeikeleesleektlelevcenelqrkkseaellrekvekleeelkelreelselsleeeeaa................. 114
                 + +lk q ++ ++ leekee+ k+  e+    +++    +ne+ r +se++ ++e++ekl++e+ +l+++l+ + +++e+++                 
  EEA19880.1 238 VATLKEQ-KQSEKGLEEKEEKKKTETEKP--ESEDFFSFDNEIPRLESEVQEKQEEIEKLSTEVDKLKRDLTVARESTESMVitlesttreleglrdfk 333
                 4455543.555555666655544433333..33446677888888888998889999999999999998888876666555577777777777766666 PP

        Fez1 115 .......lesdeakaqrqe.....aeeleelkreverlraeLkeerq 149
                        +   e k  +q+     +++le+ ++ ve+  +eL+e ++
  EEA19880.1 334 dkheselE---ELKSTKQKeiddiKSKLESAESAVEKSTTELSEVKR 377
                 65553331...333222223334466666677777777777766665 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.075
        Fez1  33 ivalkaqlrelrakleekeeeikeleesleektlelevcenelqrk.......kseaellrekvekleeelkelreelselsleeeeaa.......les 117
                 +++l +++rel+   + k+++ +elee  ++k++e++ ++++l+ +       ++e + ++ ++++ +ee+ +l++e+++++++ ++++       +e+
  EEA19880.1 316 VITLESTTRELEGLRDFKDKHESELEELKSTKQKEIDDIKSKLESAesaveksTTELSEVKRQLTEKSEEIDRLKTEAANATSQVNTSElnekislIEK 414
                 577788888888877888888888888888888885544444444433333225555555555555556666666655554443333333333322222 PP

        Fez1 118 deakaqrqe............aeeleelkre 136
                 d+a   +++            ++++++ +++
  EEA19880.1 415 DKA--DKEKrlgvieglvnklKSQVKDGEET 443
                 221..11112234444433333333333333 PP

  == domain 4  score: 3.7 bits;  conditional E-value: 0.05
        Fez1  32 eivalkaqlrelrakleekeeeikeleesleek...tlelevcenelqrk..............kseaellrekvekleeelkelreelselsleeeea 113
                 ++ al  ++ el+++l+eke++i++l+++l+     ++e+e + +el +                 e+  l+e   k+e+e+ elr + +++s+++++ 
  EEA19880.1 564 DVAALEKKIEELTEQLTEKEAAIDRLHAKLKGEddlKEEIESLRDELLNIgqehveakdqvktlLVEKAALEEARAKIEKEVVELRMNHASASADSDKL 662
                 566777777788888888888888887777644111345555555555553333444333333344444455555555555555555444444333333 PP

        Fez1 114 a....lesdeakaqrqeaeeleelkreverlraeL 144
                 +    +             e eelk++   l++ L
  EEA19880.1 663 HtdlkA-------------EFEELKHKSTTLEKDL 684
                 333331.............2222222222222222 PP

  == domain 5  score: 6.6 bits;  conditional E-value: 0.0066
        Fez1  17 qQLkdsqaevtqklseivalkaqlrelrakleek...eeeikeleesleektlelevcenelqrkkseaellrekvekleeelkelreelselsle 109
                 + L  +q+  +++ +++  lk++++ l+ +l++     +e+k+++e+l++k ++ +++en+ +  ++e++ l+  +   e+e+k l +++++ + +
  EEA19880.1 682 KDLSAAQQLAASRFKDLTDLKNTMQKLSPELKNLraeSAELKTTKEELNKKVADFKKLENKHEDLRAEVKSLKSSIADRENEVKTLNQKIRQETDS 777
                 567778888899999999999999999877665500045566667888889999999999999999999999999999999999999988875543 PP

  == domain 6  score: 8.2 bits;  conditional E-value: 0.0021
        Fez1  43 lrakleekeeeikeleesleektlelevcenelqrkkseaellrekvekleeelkelreelselsleeeeaalesdeakaqrqe.aeeleelkreverl 140
                 ++++l+++e++ +++ e+ e  +++l + ++el++ +++   ++ek ++l++el++lree++ +++++++a++ +++++ q +e a +++e +++ e l
  EEA19880.1 788 VKSDLRQSETRKQQAVETQERTSRDLSRAQEELKNLRAKMREVEEKSTQLDRELSGLREEIQLKTAQHASAQSLMTSMRDQTSEmAMQMKEARERCESL 886
                 6889*******************************************************9999888777777666666666555456778888888888 PP

        Fez1 141 raeLkeerqk 150
                 ++eL+e ++ 
  EEA19880.1 887 EEELAEAHRL 896
                 8888877664 PP

  == domain 7  score: -3.4 bits;  conditional E-value: 7.6
        Fez1  26 vtqklseivalkaqlrelrakleekeeeikeleesleektlelevcenelqrk.kseaellrekvekleeelkelreelselsleeeeaalesdeakaq 123
                  +q      +l +++r+ ++++  + +e++e  eslee  +e +++  e +r+ ++   ll+e  +++++++++++e+l+++ +e+++a+ e+++  + 
  EEA19880.1 857 SAQ------SLMTSMRDQTSEMAMQMKEARERCESLEEELAEAHRLLTERSREgETMRRLLNEIEGRTDAKVRDFKERLEAAIEERDKAEDEANT--MG 947
                 443......34444555555555555555555555555555556655565555456678899999999999999999999977666665444433..55 PP

        Fez1 124 rqeaeeleelkreverlraeLkeerqkkeeqa 155
                 r++a+eleelk +v + +++Lk  ++ kee +
  EEA19880.1 948 RRRARELEELKTKVRETEKALKAAENDKEELE 979
                 55667888888888888888888777776652 PP

  == domain 8  score: 9.5 bits;  conditional E-value: 0.00083
        Fez1   24 aevtqklseivalkaqlrelrakleekeeeikeleesleektlelevcenelqrkkseaellrekvekleeelkelree 102 
                  ae  + ++e+ +++  + +lr +l+e+e++++e+e++ +e  +++e+ +n+l++ ++ ++ l ++ +++ ++ ++  ++
  EEA19880.1  996 AE--RSAQEVKEVRQAMVQLRDALDESERQVREMEKEKSELRRSIEETNNRLEKLRKANKALTDEFSRAGTPQNGNGTA 1072
                  44..346899999******************************************999999999999988877766554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1178 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3537  (0.197278); expected 358.6 (0.02)
Passed bias filter:                      716  (0.0399353); expected 358.6 (0.02)
Passed Vit filter:                       343  (0.019131); expected 17.9 (0.001)
Passed Fwd filter:                       220  (0.0122706); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 6.24u 0.39s 00:00:06.63 Elapsed: 00:00:01.13
# Mc/sec: 3166.10
//
Query:       EEA19881.1  [L=173]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.7e-08   34.6  12.2    2.3e-08   34.2  12.2    1.1  1  MARVEL          Membrane-associating domain
  ------ inclusion threshold ------
      0.085   13.2   2.8      0.066   13.5   1.3    1.6  1  FA_hydroxylase  Fatty acid hydroxylase superfamily
        0.1   12.3   0.3       0.16   11.6   0.3    1.3  1  RasGAP          GTPase-activator protein for Ras-like GTPase
        3.1    8.1  10.4       0.29   11.3   0.8    2.5  3  DUF2069         Predicted membrane protein (DUF2069)


Domain annotation for each model (and alignments):
>> MARVEL  Membrane-associating domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.2  12.2     5e-12   2.3e-08       6     142 ..      13     132 ..      10     134 .. 0.86

  Alignments for each domain:
  == domain 1  score: 34.2 bits;  conditional E-value: 5e-12
      MARVEL   6 lgilrilqlvfaiiilgliasliakldqllgspssalnfavfvavfsflyalfllvlylfknsaftsilwplidlivdalaallwlvafialaaglrdi 104
                 l+ +r +q++ ++i+lg+ a+++     +++++ +   f ++++v+s+++++ ++v        f   l  ++  ++d +++ lwl+af++ a+  +  
  EEA19881.1  13 LLGIRTMQWASSVIALGIYAYFV-----HHQRSGTNPIFNLVISVLSVVFFIPAFVS------PFMTVLSKWVA-LIDMVFSYLWLTAFVLAAQSYNY- 98 
                 6789*******************.....44455666689999999999999999999......87888888875.56*******************99. PP

      MARVEL 105 scafesnqysasltvrcgqaqaavafgflavllfaasa 142
                    ++ ++ +a ++vr +   aa  f+fla+++ ++ +
  EEA19881.1  99 ---GD-VYLKAPSGVRVSIKHAAESFTFLAFIFTFFGL 132
                 ...44.688889999*****************998865 PP

>> FA_hydroxylase  Fatty acid hydroxylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   1.3   1.5e-05     0.066      32      89 ..      35      93 ..      24     118 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 1.5e-05
  FA_hydroxylase 32 vHHsseaptalaalrahplealllallllllllllgplsalll.vlvlaallelliHsg 89
                    vHH+ + ++++ +l  ++l++++++  ++ +++ + + +++l+ +++   +l+ ++ ++
      EEA19881.1 35 VHHQRSGTNPIFNLVISVLSVVFFIPAFVSPFMTVLSKWVALIdMVFSYLWLTAFVLAA 93
                    8************************9999999999877777774444444444444444 PP

>> RasGAP  GTPase-activator protein for Ras-like GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.3   3.6e-05      0.16     156     179 ..      43      66 ..      24      72 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 3.6e-05
      RasGAP 156 eeilnligsflflrfliPaivnPk 179
                 + i+nl++s+l  +f+iPa+v+P 
  EEA19881.1  43 NPIFNLVISVLSVVFFIPAFVSPF 66 
                 568*******************96 PP

>> DUF2069  Predicted membrane protein (DUF2069)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.8   6.5e-05      0.29      51      96 ..      16      61 ..      11      65 .. 0.91
   2 ?    5.5   4.1    0.0044        20      58     101 ..      51      94 ..      49      97 .. 0.92
   3 ?   -2.2   0.0         1   4.7e+03      56      64 ..     122     130 ..     112     144 .. 0.52

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 6.5e-05
     DUF2069 51 aytyaWasflillYfvegvvralsdegerllallevllslllfvaa 96
                 +t++Was +i l +  + v+   ++++ ++ l+  +ls+++f+ a
  EEA19881.1 16 IRTMQWASSVIALGIYAYFVHHQRSGTNPIFNLVISVLSVVFFIPA 61
                59***********9999999999999999**************966 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.0044
     DUF2069  58 sflillYfvegvvralsdegerllallevllslllfvaallyar 101
                 s l++++f+ + v+ + +  ++++al+ +++s l+++a++l a+
  EEA19881.1  51 SVLSVVFFIPAFVSPFMTVLSKWVALIDMVFSYLWLTAFVLAAQ 94 
                 78999*********************************999875 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 1
     DUF2069  56 WasflillY 64 
                 +++f+  ++
  EEA19881.1 122 FLAFIFTFF 130
                 333333332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (173 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       730  (0.0407162); expected 358.6 (0.02)
Passed bias filter:                      302  (0.0168442); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.43u 0.28s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 1220.89
//
Query:       EEA19882.1  [L=125]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.9e-08   33.1   7.9    6.2e-08   32.8   7.9    1.1  1  MARVEL          Membrane-associating domain
  ------ inclusion threshold ------
      0.016   15.6   0.8      0.018   15.4   0.8    1.2  1  FA_hydroxylase  Fatty acid hydroxylase superfamily
      0.052   13.2   0.2       0.08   12.6   0.2    1.3  1  RasGAP          GTPase-activator protein for Ras-like GTPase
       0.34   11.1   8.0       0.15   12.3   0.8    2.1  2  DUF2069         Predicted membrane protein (DUF2069)


Domain annotation for each model (and alignments):
>> MARVEL  Membrane-associating domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.8   7.9   1.4e-11   6.2e-08       6     134 ..      13     124 ..      10     125 .] 0.84

  Alignments for each domain:
  == domain 1  score: 32.8 bits;  conditional E-value: 1.4e-11
      MARVEL   6 lgilrilqlvfaiiilgliasliakldqllgspssalnfavfvavfsflyalfllvlylfknsaftsilwplidlivdalaallwlvafialaaglrdi 104
                 l+ +r +q++ ++i+lg+ a+++     +++++ +   f ++++v+s+++++ ++v        f   l  ++  ++d +++ lwl+af++ a+  +  
  EEA19882.1  13 LLGIRTMQWASSVIALGIYAYFV-----HHQRSGTNPIFNLVISVLSVVFFIPAFVS------PFMTVLSKWVA-LIDMVFSYLWLTAFVLAAQSYNY- 98 
                 6789*******************.....44455666689999999999999999999......87888888875.56*****************9998. PP

      MARVEL 105 scafesnqysasltvrcgqaqaavafgfla 134
                    ++ ++ +a ++vr +   aa  f+fla
  EEA19882.1  99 ---GD-VYLKAPSGVRVSIKHAAESFTFLA 124
                 ...34.577778888889999999999987 PP

>> FA_hydroxylase  Fatty acid hydroxylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.4   0.8   4.1e-06     0.018      32      89 ..      35      93 ..      20     118 .. 0.77

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 4.1e-06
  FA_hydroxylase 32 vHHsseaptalaalrahplealllallllllllllgplsalll.vlvlaallelliHsg 89
                    vHH+ + ++++ +l  ++l++++++  ++ +++ + + +++l+ +++   +l+ ++ ++
      EEA19882.1 35 VHHQRSGTNPIFNLVISVLSVVFFIPAFVSPFMTVLSKWVALIdMVFSYLWLTAFVLAA 93
                    8************************9999999999877777774544444444454444 PP

>> RasGAP  GTPase-activator protein for Ras-like GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.2   1.8e-05      0.08     156     179 ..      43      66 ..      21      73 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.8e-05
      RasGAP 156 eeilnligsflflrfliPaivnPk 179
                 + i+nl++s+l  +f+iPa+v+P 
  EEA19882.1  43 NPIFNLVISVLSVVFFIPAFVSPF 66 
                 568*******************96 PP

>> DUF2069  Predicted membrane protein (DUF2069)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.8   3.3e-05      0.15      51      96 ..      16      61 ..      10      65 .. 0.91
   2 ?    6.4   4.1    0.0023        10      58     101 ..      51      94 ..      49      97 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 3.3e-05
     DUF2069 51 aytyaWasflillYfvegvvralsdegerllallevllslllfvaa 96
                 +t++Was +i l +  + v+   ++++ ++ l+  +ls+++f+ a
  EEA19882.1 16 IRTMQWASSVIALGIYAYFVHHQRSGTNPIFNLVISVLSVVFFIPA 61
                59***********9999999999999999**************966 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.0023
     DUF2069  58 sflillYfvegvvralsdegerllallevllslllfvaallyar 101
                 s l++++f+ + v+ + +  ++++al+ +++s l+++a++l a+
  EEA19882.1  51 SVLSVVFFIPAFVSPFMTVLSKWVALIDMVFSYLWLTAFVLAAQ 94 
                 78999*********************************999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (125 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       886  (0.0494171); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.43u 0.24s 00:00:00.67 Elapsed: 00:00:00.40
# Mc/sec: 941.68
//
Query:       EEA19883.1  [L=402]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.8e-19   68.6   0.1      5e-19   67.8   0.1    1.4  1  zinc_ribbon_10  Predicted integral membrane zinc-ribbon metal
  ------ inclusion threshold ------
       0.13   11.4   0.7        3.2    6.9   0.0    2.1  2  Zip             ZIP Zinc transporter


Domain annotation for each model (and alignments):
>> zinc_ribbon_10  Predicted integral membrane zinc-ribbon metal-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.8   0.1   5.6e-23     5e-19       1      54 []     253     309 ..     253     309 .. 0.93

  Alignments for each domain:
  == domain 1  score: 67.8 bits;  conditional E-value: 5.6e-23
  zinc_ribbon_10   1 wfDrvldvLvGddetsaknryalICskChshnGlap...keeleevkyrCpkCgaln 54 
                     w+Dr++dvL+G+dets knr+ lIC++C+ +nG+ap   k+  e  ++rC +Cga+n
      EEA19883.1 253 WYDRLMDVLLGEDETSPKNRLVLICQNCRLVNGQAPpgiKSLGELGRWRCGSCGAWN 309
                     9***********************************9955555555**********8 PP

>> Zip  ZIP Zinc transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.0   0.00036       3.2      76     171 ..      75     165 ..      30     248 .. 0.83
   2 ?   -0.5   3.9     0.063   5.7e+02     117     178 ..     325     386 ..     305     397 .. 0.61

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.00036
         Zip  76 plagllvllGflllllveklltmivekksshkektpkkasssssesaakksvsndkveeseekedhvaeadtdadskeelrngkqeksesekeqas 171
                  +  ++vl+G +++++v  + + +++      +++ ++ + +s ++++ +++++ kv ++ +++++  e+ + ++ k +++n+++++++++  q++
  EEA19883.1  75 YWEWGAVLGGPFVVYTVRTVGSRMFDY-----RINRSQNYLDSLNKQRDETIEKLKVATKYNSTQQLLEKYGGESPKPKTANKNGGTKKKDNDQQQ 165
                 6777899*************9999999.....9999999999999999999999999999999888777666655555555555555554444433 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.063
         Zip 117 sssesaakksvsndkveeseekedhvaeadtdadskeelrngkqeksesekeqaseeedkek 178
                 + +e + + ++ +d+++ see+ d +   +++ + +  ++ +kqe  + ++e++ +++++++
  EEA19883.1 325 EVTEDRQAAKMADDEMSASEENDDGELISKEEGEDEGDEQSEKQEEIQTIPEKTGTTQSEPQ 386
                 44455666667777777777775555555555555555555555555555555554444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (402 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1776  (0.0990574); expected 358.6 (0.02)
Passed bias filter:                      748  (0.0417201); expected 358.6 (0.02)
Passed Vit filter:                        86  (0.0047967); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.32s 00:00:00.95 Elapsed: 00:00:00.46
# Mc/sec: 2623.23
//
Query:       EEA19884.1  [L=600]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.5e-08   33.4   9.9    7.7e-08   32.3   9.9    1.5  1  Zn_clus      Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
       0.33    9.3   1.4       0.57    8.5   1.4    1.3  1  Herpes_pp85  Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV U
       0.57    9.7   2.5        1.3    8.6   2.5    1.5  1  SR-25        Nuclear RNA-splicing-associated protein


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.3   9.9   1.3e-11   7.7e-08       1      36 [.      12      46 ..      12      49 .. 0.94

  Alignments for each domain:
  == domain 1  score: 32.3 bits;  conditional E-value: 1.3e-11
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfyses 36
                ++Cd+C+ ++++C +++P+Cs+C + + +Ct y++s
  EEA19884.1 12 TGCDTCKIRRIRCTEEHPQCSKCTSTGRKCT-YTDS 46
                58*****************************.9876 PP

>> Herpes_pp85  Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   1.4   9.6e-05      0.57     466     514 ..     359     407 ..     336     413 .. 0.67

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 9.6e-05
  Herpes_pp85 466 egrdlfadvfrrpvtdaaasssassssssasPnsvslpsdrssst.rtrv 514
                   ++  f  ++    t + +sss ssssss  P+ v+   + s +t  +r 
   EEA19884.1 359 LHKHAFEKILDYADTISSSSSSSSSSSSSVPPP-VAAAGAISHTTiGERQ 407
                  455567777777777777777766666666555.5777777777654444 PP

>> SR-25  Nuclear RNA-splicing-associated protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   2.5   0.00021       1.3      67      80 ..     374     387 ..     344     398 .. 0.59

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00021
       SR-25  67 ssssssssssssss 80 
                  sssssssssssss
  EEA19884.1 374 ISSSSSSSSSSSSS 387
                 22222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (600 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       595  (0.0331865); expected 358.6 (0.02)
Passed bias filter:                      403  (0.0224776); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.27s 00:00:00.89 Elapsed: 00:00:00.43
# Mc/sec: 4152.87
//
Query:       EEA19885.1  [L=1546]
Description: Patatin-like serine hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-28   99.0   0.6    2.7e-17   62.6   0.0    5.6  6  cNMP_binding  Cyclic nucleotide-binding domain
    4.2e-17   63.0   7.2    4.2e-12   46.7   2.8    3.4  3  Patatin       Patatin-like phospholipase


Domain annotation for each model (and alignments):
>> cNMP_binding  Cyclic nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.8   0.0    0.0016        15       2      39 ..     222     257 ..     221     266 .. 0.88
   2 ?    1.6   0.0     0.033   2.9e+02      66      87 ..     415     436 ..     408     438 .. 0.91
   3 !   12.3   0.0   1.5e-05      0.13       2      30 ..     728     756 ..     727     781 .. 0.83
   4 !    9.4   0.0   0.00012       1.1      41      89 .]     805     853 ..     797     853 .. 0.86
   5 !   62.6   0.0     3e-21   2.7e-17       2      89 .]     882     969 ..     881     969 .. 0.94
   6 ?   -3.4   0.0       1.2     1e+04      59      75 ..    1097    1113 ..    1095    1114 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0016
                   EEE-TT-EEE-TTSB-SEEEEEEES-EEEEEEETTS.E CS
  cNMP_binding   2 rsfkagevifrqGdpadslyivlsGevrvyrlsedgke 39 
                   r++ age+++ + ++  ++++v+ G v+++ +s  g+e
    EEA19885.1 222 RKLMAGETLLLEEEK--GFCLVVDGLVQIFVKSIRGNE 257
                   78899*********9..5***********988888877 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.033
                   EEESSTEEEEEEEHHHHHHHHH CS
  cNMP_binding  66 vvAltdsellalprddflellq 87 
                   ++A+ d++++ +p+++f++l +
    EEA19885.1 415 ARAMVDTTIAIIPASAFRRLTR 436
                   79****************9965 PP

  == domain 3  score: 12.3 bits;  conditional E-value: 1.5e-05
                   EEE-TT-EEE-TTSB-SEEEEEEES-EEE CS
  cNMP_binding   2 rsfkagevifrqGdpadslyivlsGevrv 30 
                   +sf++g+v+++qG++  +ly+v+ G + v
    EEA19885.1 728 VSFPQGSVLVEQGERNPGLYYVIDGFLDV 756
                   79*************99********9988 PP

  == domain 4  score: 9.4 bits;  conditional E-value: 0.00012
                   EEEEE-TTEEESHHHHHHTS--SSEEEESSTEEEEEEEHHHHHHHHHH- CS
  cNMP_binding  41 vlavlgpGdlfGelalltgeprtatvvAltdsellalprddflellqqd 89 
                    l  ++pG + G ++ +   ++ ++vvA+td+ l +lpr++++++ +++
    EEA19885.1 805 SLYLIKPGGMQGYVGSVASYRSFTDVVAKTDVYLGFLPRATLERIAERY 853
                   5677899999999999976678889*******************98875 PP

  == domain 5  score: 62.6 bits;  conditional E-value: 3e-21
                   EEE-TT-EEE-TTSB-SEEEEEEES-EEEEEEETTS.EEEEEEE-TTEEESHHHHHHTS--SSEEEESSTEEEEEEEHHHHHHHHHH- CS
  cNMP_binding   2 rsfkagevifrqGdpadslyivlsGevrvyrlsedgkevvlavlgpGdlfGelalltgeprtatvvAltdsellalprddflellqqd 89 
                   +++ ag+vi +qGd  d +yivl G++r +   + gk +vl+++g+G+ +Gel+++t+++r+at+ A+ d+el+++pr+ f++l q++
    EEA19885.1 882 VQVTAGQVIHHQGDDSDAIYIVLNGRLRSVLEGKGGKIRVLGEYGQGESVGELEVMTESTRPATLHAIRDTELAKFPRSLFNSLAQEH 969
                   5789*************************9666677779********************************************99986 PP

  == domain 6  score: -3.4 bits;  conditional E-value: 1.2
                    TS--SSEEEESSTEEEE CS
  cNMP_binding   59 geprtatvvAltdsell 75  
                    ++p+t t++++ d+ ll
    EEA19885.1 1097 NSPWTQTCITQADCILL 1113
                    57999*********998 PP

>> Patatin  Patatin-like phospholipase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.1       0.3   2.7e+03     106     106 ..     518     518 ..     411     714 .. 0.56
   2 !   46.7   2.8   4.6e-16   4.2e-12       1      49 [.    1243    1290 ..    1243    1301 .. 0.94
   3 !   16.4   0.0   8.7e-07    0.0078     152     200 ..    1355    1403 ..    1349    1406 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.3
     Patatin 106 l 106
                 +
  EEA19885.1 518 I 518
                 0 PP

  == domain 2  score: 46.7 bits;  conditional E-value: 4.6e-16
     Patatin    1 LvlsGGGsrgafslgalkaLkkelgerfdiisGtSaGAiialllalgrd 49  
                  Lvl+GGG+rg++++g++ka+ +e+g+ +di++GtS+G++i++l+a   d
  EEA19885.1 1243 LVLGGGGARGIAHVGVIKAI-EEAGIPIDIVGGTSIGSFIGALYARDAD 1290
                  8*******************.**********************998755 PP

  == domain 3  score: 16.4 bits;  conditional E-value: 8.7e-07
     Patatin  152 nglytedddddvdladavraSsafPglfppvsldgelyvDGGilsNvPi 200 
                   + ++ ++   + +++ vraS+++ gl+pp   +g l++DGG ++N+ +
  EEA19885.1 1355 ISKSRNEFHSSGYVWRYVRASMSLAGLLPPLCDEGSLLLDGGYVDNLTV 1403
                  5566777778999*********************************866 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1546 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       707  (0.0394333); expected 358.6 (0.02)
Passed bias filter:                      434  (0.0242066); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.86u 0.29s 00:00:01.14 Elapsed: 00:00:00.43
# Mc/sec: 10810.23
//
Query:       EEA19886.1  [L=608]
Description: beta-glucosidase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.3e-73  245.7   1.7    1.6e-70  237.8   1.7    2.6  1  Glyco_hydro_1  Glycosyl hydrolase family 1
  ------ inclusion threshold ------
       0.48    8.9   1.5        2.5    6.5   0.0    2.0  2  Herpes_UL6     Herpesvirus UL6 like


Domain annotation for each model (and alignments):
>> Glyco_hydro_1  Glycosyl hydrolase family 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  237.8   1.7   1.8e-74   1.6e-70       4     441 ..     150     593 ..     148     603 .. 0.85

  Alignments for each domain:
  == domain 1  score: 237.8 bits;  conditional E-value: 1.8e-74
                    GS-TT-EEEEE--HHHHH--TTSTT---BHHHHHHHHGGGSTTS---SSTT-HHHHHHHHHHHHHHTT-SEEEEE--HHHHSTTS..TT---HHHH CS
  Glyco_hydro_1   4 tfpedFlwgaataayqiEGawnedGkgesiwDtftetpgkvlegsngdvacdsYhrykeDvallkelgvkayrfSisWpRilPkG..egeinekGl 97 
                    +fpe+F++g+a +a qiEGa   +G+ +si ++    p    +     v+ + Y  yk+D++ l+ +gvk y fSisW RilP     + ine+G+
     EEA19886.1 150 NFPEGFTFGVAGSAAQIEGAIGLEGRAPSILEKML--PDTKPQ---DYVTNENYYLYKRDIQRLASIGVKYYSFSISWGRILPFTvpGSPINEQGI 240
                    6*****************************99544..322333...4478899******************************9887899****** PP

                    HHHHHHHHHHHHTT-EEEEEEESS--BHHHH.............HH-GGG-SHHHHHHHHHHHHHHHHHTTT--EEEEEE-HHHHHHHHHTSS-ST CS
  Glyco_hydro_1  98 ayYerLidelleagieplvTlyHwdlPqaLq.............deGgwenrsiidafkeyaevvfkrfgdkvklwlTfnEpnvvallgyltgefa 180
                    ++Y+ Lid +l  g+ p+vT+ H+d+P  +              ++Gg+ n++ ++ f +y +++f++f d+v +w+T+nEp +  +         
     EEA19886.1 241 KHYNDLIDYVLLVGMVPIVTMLHFDTPLYFLnasagyvtpdigyQNGGYWNEEFVNSFVNYGKILFTHFADRVPFWVTINEPLLYGF--------- 327
                    ***************************764312222222222224689999*******************************86532......... PP

                    T-S-TTTHHHHHHHHHHHHHHHHHHHHHHHT.TT-EEEEEEEEEEEEESSSSHHHH.HHHHHHHHHHTHHHHHHHHHS.S--HHHHHHHGGG..S- CS
  Glyco_hydro_1 181 PgkkdleaayeaaHnlllaharavklykeva.qkgkigivlnlslaeplseseedk.eaaeraleflngwfldpvvkG.dYpeemkellrergalp 273
                             ++   n++ aha+ ++ y+++   +gk+g+ l+ +  +p++++++ + eaa+r  ++++g f+ p++ G +Yp+++ ++l      +
     EEA19886.1 328 --------NFTGLDNVVHAHAELYHFYHDTLnGTGKVGLKLSDNFGVPKNPENQTEiEAANRFNDMQLGVFAYPICLGqQYPTSILNTLPGA---K 412
                    ........2445668899***********98689*****************999877********************836999888877655...8 PP

                    ---HHHHHHHTT--SEEEEEEEEEEEEEE--...-STT---SSGGGGG-.............SBSS-B-SSSS-B-HHHHHHHHHHHHHTS----E CS
  Glyco_hydro_1 274 eiteedkellkgkadflglnyYtsrlvknkeseeaslskteekkleeev.............dpslpktdigwiiepeglrkllellkkeYqklpi 356
                     + ++++e l +++df+g++ Yt  +++    e ++  ++++  +++ +               +  +++++  i+p+ lr  l++l + Y+ +pi
     EEA19886.1 413 PLSKNELEYLGKTTDFIGIDAYTAAVISVPG-EGIEKCAKQNMATNSLYpycvtqetvntygWDIGYRSQSYVYITPIYLRPYLSYLWNTYK-TPI 506
                    899**********************998766.44444444444444444888998888776644556777778888***************9.9** PP

                    EEEE----EE-BSSS...HHH--HHHHHHHHHHHHHHHHHH.HTT--EEEEEEE-SB----GGGTTSEE--SEEEETTTTTEEEE-HHH CS
  Glyco_hydro_1 357 yiteNGlgakdeiee...gkveDdkRidYlkehlnevkkai.edgvdlkgYvawsllDnfewaegyskrfGlvyvdrnetleRtpkkSa 441
                     ++e G ++  e +     ++ D+ R +Y+ ++++ev ++i edgv++ g +aws++Dn e    y ++fG+  v+  +t+eR  kkS+
     EEA19886.1 507 ILSEFGFPVYAESTRdlvDQLYDSPRSQYYLSFMSEVLRSIwEDGVNVIGAIAWSFMDNWEF-GDYAQQFGMQVVN-RTTQERWFKKSF 593
                    *******99887766699999*************************************9875.45***********.99********97 PP

>> Herpes_UL6  Herpesvirus UL6 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.0   0.00028       2.5     112     136 ..     236     260 ..     230     270 .. 0.90
   2 ?    1.1   0.4     0.012   1.1e+02     514     557 ..     491     538 ..     476     543 .. 0.78

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.00028
  Herpes_UL6 112 qskgnssyerYvDWivtvGlVPvvr 136
                 +++g ++y+  +D++  vG+VP+v 
  EEA19886.1 236 NEQGIKHYNDLIDYVLLVGMVPIVT 260
                 678899*****************96 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.012
  Herpes_UL6 514 vgPflesilkltrlelvtese....vslsleeiaealykksrlavYle 557
                 + P+l+ + + ++  ++  ++       s  +++++ly++ r + Yl+
  EEA19886.1 491 LRPYLSYLWNTYKTPIILSEFgfpvYAESTRDLVDQLYDSPRSQYYLS 538
                 67888888888888877666533324689*****************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (608 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       390  (0.0217525); expected 358.6 (0.02)
Passed bias filter:                      315  (0.0175693); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.42
# Mc/sec: 4351.34
//
Query:       EEA19887.1  [L=1556]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.8e-40  138.5   0.0    4.9e-40  137.7   0.0    1.3  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    4.5e-08   32.8   0.1    1.4e-07   31.2   0.1    1.8  1  gag_pre-integrs  GAG-pre-integrase domain
    5.9e-07   29.7   0.1    1.1e-05   25.6   0.0    2.6  2  rve              Integrase core domain
    0.00017   21.3   0.8       0.12   12.2   0.0    3.3  2  rve_3            Integrase core domain


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.7   0.0   1.1e-43   4.9e-40      12     241 ..    1076    1303 ..    1067    1304 .. 0.91

  Alignments for each domain:
  == domain 1  score: 137.7 bits;  conditional E-value: 1.1e-43
       RVT_2   12 rkaigsrWvftkkkddl.kevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeeelvvhqldvdsafLnaeldee.vyvkqPpGfeid 106 
                     +g+rWvft k d+     +ykarlv++G  q+    +d++++  i  +++r l+ala+  ++v++q d+ +a+Lna +d++  +++ P G + d
  EEA19887.1 1076 YELLGTRWVFTYKLDSAgFLLRYKARLVIRGDLQM---SWDDTYSATISSKAIRALIALATAFGYVMWQHDMITAYLNAGIDKNgYFIRMPQGLKGD 1169
                  5669*********99887899**********9997...599******************************************98999******999 PP

       RVT_2  107 reeekvykLnkslyGlkqapllWnekidkvLkklgferseaesGlyvrgtgegklivalyvddll..iagsdikiledvkkelakkfklkdlgkvsk 201 
                    ++   +L k+lyGlkq+pllW+++ + +L +lgf++++ e  l+  +   + +i+  yvdd++     ++  + +++  +l +k+  + +g++s 
  EEA19887.1 1170 --PDIWLRLRKALYGLKQSPLLWQQEFTATLIQLGFKQISEEVCLFKNK---DGIILFFYVDDVVtlFRPEQEALAKELWDRLMNKYPARAMGDLSW 1261
                  ..9******************************************9887...55999******972134566778899******************* PP

       RVT_2  202 fLGieiaq..eaggiklsladyiakvvkkfeltdaktvatPl 241 
                  fLG  +++  e +   l++  yi++v+k  +l ++k   tP 
  EEA19887.1 1262 FLGTRVIRdkEDEASYLCQDSYIEEVAKRYNLDTSKRPSTPC 1303
                  ******9943455678*******************9999985 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.2   0.1   3.2e-11   1.4e-07      20      65 ..     483     528 ..     459     530 .. 0.82

  Alignments for each domain:
  == domain 1  score: 31.2 bits;  conditional E-value: 3.2e-11
  gag_pre-integrs  20 nkssinlWHrRLGHpsfsrlkkLfkkgllpglkisksevCeaCqlg 65 
                      +k s+++WH+RLGHp+ + +++L ++   + ++    ++Ce+C ++
       EEA19887.1 483 SKASLERWHKRLGHPNDEVINHLKDSVTGAEVDTTTRPICESCKIS 528
                      57899*******************98888888999999*****976 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.0   2.4e-09   1.1e-05       3     111 ..     544     649 ..     542     656 .. 0.86
   2 ?    0.8   0.0      0.12   5.5e+02      56      94 ..    1456    1497 ..    1430    1506 .. 0.77

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 2.4e-09
         rve   3 rpgelwqvDvtvvripdgggkayllvvvddfsrlilaealsdemdastvlalleravarfggvepervlsDngseytskafrefladlgirvsftrpgr 101
                 +p e+ + D+  ++  +++g ++++++ +  s+   a+++ ++   s+++   e+  ar+g + ++++++D  ++   + f + +++ gi++  ++p++
  EEA19887.1 544 APWEIAHFDIIPMS-ESWDGMKWCIHFYCLQSGDHEAVHVHSKRVLSSAVIDFEKEKARQGLK-IKVFHTDGERSLN-EMFIAHIRNEGIQLHQSAPYS 639
                 688999*****888.7888899**********9999999999977777777777788888887.9******776655.9******************** PP

         rve 102 pqdnGkvErf 111
                 pq+nG +Er 
  EEA19887.1 640 PQQNGPAERS 649
                 ********97 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.12
         rve   56 eravarfggvepervlsDngseytsk....afrefladlgirv 94  
                  e a+++  +++p ++ +Dn  ++++     a+++ l++ +i+ 
  EEA19887.1 1456 E-AIEFDPEQGPITIECDNRQTVRAMikheAIQTRLRHVDIHN 1497
                  3.667777777*********99998788899999999988875 PP

>> rve_3  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.7   0.2    0.0029        13      40      57 ..     149     166 ..     136     169 .. 0.86
   2 !   12.2   0.0   2.6e-05      0.12       2      22 ..     629     649 ..     628     656 .. 0.92

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0029
       rve_3  40 aearekleawredYNteR 57 
                 ++ ++++++w+e YN++R
  EEA19887.1 149 KQFNAWIKSWIETYNRAR 166
                 67899**********999 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 2.6e-05
       rve_3   2 gielsyiapgkPqqNglvEsf 22 
                 gi+l+ +ap++PqqNg +E++
  EEA19887.1 629 GIQLHQSAPYSPQQNGPAERS 649
                 9******************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1556 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       723  (0.0403257); expected 358.6 (0.02)
Passed bias filter:                      470  (0.0262145); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.96u 0.31s 00:00:01.27 Elapsed: 00:00:00.52
# Mc/sec: 9050.55
//
Query:       EEA19888.1  [L=708]
Description: RNA polymerase II mediator complex component SRB4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   3.1e-114  382.3   6.7     5e-114  381.5   6.7    1.3  1  Med17     Subunit 17 of Mediator complex


Domain annotation for each model (and alignments):
>> Med17  Subunit 17 of Mediator complex
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  381.5   6.7  2.8e-118    5e-114      37     458 ..      17     434 ..       4     438 .. 0.94

  Alignments for each domain:
  == domain 1  score: 381.5 bits;  conditional E-value: 2.8e-118
                 SS-CCHHHCCHHCCCHCCHHHHHHCHHHHHHHCCHHHHHSS-S---GGGTTCHHHHHHHHHGGG...SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
       Med17  37 evfgqekLaqliprIlqergefrdlsEesLreeiekekqqkeekdeeeeeeeeeeekkeDaedklltqeefaklrkemiekinlAknesslaLdfisLL 135
                 ++ ++ +L   i +I+++rg+fr+++E+sL+eei + k+++++k++e+eeee+++ek+++  d +  q+ + k r e+i+   +A+ e+++aLdfisLL
  EEA19888.1  17 KTTKKDNLPIRIAQINAQRGSFRNITEQSLQEEITAHKEKSKDKASENEEEEDQDEKNVNEVDATERQDLLYKKRAEIIQFAAQAHMETQFALDFISLL 115
                 34678999999*******************************999999999999999999877788999****************************** PP

                 CTTCHCCCCHCCSSHHHCCCTHCCHCCCCCHHHHHHHHSHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTCCCCCCCEEEEEC CS
       Med17 136 lSkvressaassmSpfLkkvvppgSLnadkvpkpkktkkeklelevlnkGwklksLneardllkkaaakLkkevekEhkyWkeiqnisnkdvgwklrdk 234
                 lSk  +++a  s+Sp+Lk++vp+gSLn+d v +p+k++++ ++++++++Gwk++s + +++ l kaa++L++ev +E+kyW+++  +s+kd+gwk+++ 
  EEA19888.1 116 LSKHAPRQAETSISPYLKQNVPLGSLNIDVVRAPQKSQSALRDSQNVARGWKMESFDASATRLLKAASRLESEVAAETKYWDQV--LSIKDKGWKVCRL 212
                 ************************************************************************************..************* PP

                 CCCCCCEEEECCCCCHCC-..SEEEEEEEECTTTCCEEEC-SSSSSSEEEEEEEEEC.TTTSSEEEEEE----..SS----TTCHHHHHHHHHHHHHHH CS
       Med17 235 stgerslgvkygyedsgstfkdrgiAeLrrndegsklllvpllgskekflrVriftkieseddyilsgessld..eslkesdsdirkqieeakktiFek 331
                 + +++ lgv+yg+ ++++tf+drg+A Lrr d+g  +l+ +l+ s+ +++rVr+      +++++++g+ssl+       sd++++k+i + ++t+Fe+
  EEA19888.1 213 PRERQVLGVQYGFMEAAPTFRDRGLASLRRADDGTLVLDKGLVPSRARAVRVRV------KKQGKITGSSSLSqfVAAAVSDDSVEKTILQSRDTLFEE 305
                 ******************************************************......6789999999999887888999***************** PP

                 HHHHHHHHHHHHCCCCTEEECCCCEEEEC.SSCCCEEEEECCCCEGGGTSTTTTTT..TTHHHHHHCHHHHHHHHHHHHHHHHHHC..CTCCCHCTSSS CS
       Med17 332 ELfyelkkEaqqLisygVeiennkiviel.pnekleielvslddsslvnheqdapk..sndkranlilitlrllLvvifkknlrkr..lasskttakas 425
                 ELf+el++Ea+ L+s gV++ ++ i +e+ p e++ +++v+++d ++ ++   a++  +n+  a+ i+ +lr+lL++++++nlr+r   +++    +++
  EEA19888.1 306 ELFHELTREARVLVSSGVTTHKDMIEFEYePGEQILLDIVDMNDIKPDSEMDSAENgtVNNLEAKAIAHALRILLSYAHRQNLRRRsqFPPPL---TKQ 401
                 ********************************************99998877777699****************************7666666...444 PP

                 SSCHHCTTTCHHHHHHHHHHHHHHHHHHHHHCC CS
       Med17 426 rslpkdillLrPilgklrhenyvdllrkilkkl 458
                 +++ +++ lLrPil++++h  +v +l+++l+++
  EEA19888.1 402 PRATPQYQLLRPILSYMQHDAHVRSLQSFLQDV 434
                 445559************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (708 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1520  (0.0847788); expected 358.6 (0.02)
Passed bias filter:                      613  (0.0341904); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.73u 0.31s 00:00:01.04 Elapsed: 00:00:00.48
# Mc/sec: 4440.46
//
Query:       EEA19889.1  [L=420]
Description: IMP-specific 5'-nucleotidase (Isn1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.7e-197  655.6   0.0   3.1e-197  655.5   0.0    1.0  1  ISN1      IMP-specific 5'-nucleotidase


Domain annotation for each model (and alignments):
>> ISN1  IMP-specific 5'-nucleotidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  655.5   0.0  1.7e-201  3.1e-197       1     411 []       1     405 [.       1     405 [. 1.00

  Alignments for each domain:
  == domain 1  score: 655.5 bits;  conditional E-value: 1.7e-201
        ISN1   1 mtsryrveyalkshrrdefiewikgllavpfvlhsqseavaeeeekseakvaeevkrryaeilkdvekliddkielqkekkkekskLklLvPsigkfft 99 
                 mt+ryrveyalk+hrrd++iewikgllavpfvlhsq++ +++ee  + a+va+++++ryaei++dve li+d+i++++++   kskLklLvP+ig+fft
  EEA19889.1   1 MTTRYRVEYALKTHRRDQLIEWIKGLLAVPFVLHSQPTVIFHEEGVKLAAVATATQKRYAEIMHDVELLINDHIHHENANLPGKSKLKLLVPAIGQFFT 99 
                 9************************************************************************************************** PP

        ISN1 100 kLpleeaflvedkkraissrrlvaPsfnDvrlilntaqilaltkakklklvtfDGDvtlydDGksleednpvikrllkllkkdvkvgivtaaGyteaek 198
                 +L le+af+++d++r+is+rr+vaPsfnDvrl+lntaq++ l+++++++l+tfDGDvtly+DG +l++d+pv++rl+kll ++ k+givtaaGyte ++
  EEA19889.1 100 PLLLEDAFIYQDQRRHISRRRFVAPSFNDVRLTLNTAQLMGLVRSSAISLLTFDGDVTLYEDGCCLVDDDPVLPRLMKLLGQGKKIGIVTAAGYTEPSH 198
                 *************************************************************************************************** PP

        ISN1 199 yeerlkGLldalkaseelteeqkenllvmGgesnylfryseeskellklvereeWllpemkaWseedikalldvaekalrelakklklpatilrkerav 297
                 y+ rlkGLlda++++++lt++qk+ l+vmGgesn+lfry++++++ll++v+r+eWll+em++W+++di++lldvae++lre++++l+lpa++lrkerav
  EEA19889.1 199 YYVRLKGLLDAVRNDTSLTPDQKSGLIVMGGESNFLFRYDQSADHLLTYVPRSEWLLDEMHTWDDKDIEQLLDVAEASLRECVSNLSLPAMVLRKERAV 297
                 *************************************************************************************************** PP

        ISN1 298 GivpsekevklareqLeevvlvvqkklelseaareikfcafnGGsDvfvDiGdkslGvevlqkyfgkeekaeikkeetlhvGDqflsaganDfkarlaa 396
                 G++p++ ++k++reqLee+vlvvq+++e+s+++++++fcafnGG+Dvf+DiGdks+Gv+++q+yfg+     i+++ tlhvGDqflsaganDfkar+a+
  EEA19889.1 298 GVYPTK-GHKMHREQLEETVLVVQNMVERSDVGKKLPFCAFNGGNDVFIDIGDKSWGVRACQRYFGG-----IDRSMTLHVGDQFLSAGANDFKARTAC 390
                 *****9.************************************************************.....999************************ PP

        ISN1 397 ttvWiasPaetvell 411
                 tt+Wia+Paetv+ll
  EEA19889.1 391 TTAWIANPAETVQLL 405
                 ************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (420 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       483  (0.0269396); expected 358.6 (0.02)
Passed bias filter:                      462  (0.0257683); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.50
# Mc/sec: 2549.46
//
Query:       EEA19890.1  [L=293]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.5e-09   37.0   0.4    7.2e-08   33.1   0.4    2.3  1  DUF4646   Domain of unknown function (DUF4646)
  ------ inclusion threshold ------
       0.16   12.1   0.0        1.1    9.4   0.0    2.0  1  Erf4      Golgin subfamily A member 7/ERF4 family


Domain annotation for each model (and alignments):
>> DUF4646  Domain of unknown function (DUF4646)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.1   0.4     8e-12   7.2e-08      21     125 .]      62     186 ..      47     186 .. 0.68

  Alignments for each domain:
  == domain 1  score: 33.1 bits;  conditional E-value: 8e-12
     DUF4646  21 slesrkkeledgFpelaPpskavphpl.vthdVseedWkrFledikaaaalstaek...............iaagv...aplal.....slg.llgllv 94 
                  + s+ + l++gF+        +p  l  + ++s+edW+rF+++i+++a+ls ++                i++g+   +p ++     +    ++ lv
  EEA19890.1  62 QIPSKTSRLTSGFE--------YPSILgSNYNISKEDWERFTHEITESAKLSSSQWstvigaglgimavggIMVGFfgaIPAVIvakrkRAAqESKNLV 152
                 57788899******........555663678*********************999999*9999999999995555455544444222222222333333 PP

     DUF4646  95 skaiekkmkk....kkegsvgelieqWnesfFkpR 125
                 +  +e++ ++      e+++   i+ Wne+fFkpR
  EEA19890.1 153 RA-MENQQQDeeeeGDENTLSFKINEWNETFFKPR 186
                 33.333333211223345566679**********9 PP

>> Erf4  Golgin subfamily A member 7/ERF4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.0   0.00012       1.1      21     104 ..      76     190 ..      66     197 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00012
        Erf4  21 lppeL.sgy.iseeefeeiinkiNeilaeafspysvrnildnvlglltly.lwslvlk.......thykkklkk......................... 84 
                 +p++L s+y is+e++e++ ++i e  + + s  ++++++   lg++ ++ ++  ++        ++ k+                             
  EEA19890.1  76 YPSILgSNYnISKEDWERFTHEITESAKLSSS--QWSTVIGAGLGIMAVGgIMVGFFGaipavivAKRKRA--Aqesknlvramenqqqdeeeegdent 170
                 77777345589************977666666..6999999999988766433333334665543333333..24477777788888888999999999 PP

        Erf4  85 lekyieelNeelfkerglki 104
                 l+  i+e+Ne++fk+rg+ i
  EEA19890.1 171 LSFKINEWNETFFKPRGIMI 190
                 99999999999999999865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (293 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1079  (0.0601818); expected 358.6 (0.02)
Passed bias filter:                      678  (0.0378158); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.32s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 1860.25
//
Query:       EEA19891.1  [L=285]
Description: conserved mitochondrial protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (285 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       283  (0.0157845); expected 358.6 (0.02)
Passed bias filter:                      275  (0.0153383); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 2002.89
//
Query:       EEA19892.1  [L=370]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (370 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       288  (0.0160634); expected 358.6 (0.02)
Passed bias filter:                      279  (0.0155614); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.48u 0.24s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2616.80
//
Query:       EEA19893.1  [L=420]
Description: aspergillopepsin A precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-48  165.2   0.2    2.9e-48  164.9   0.2    1.1  1  Asp       Eukaryotic aspartyl protease
     0.0052   16.6   0.0       0.13   12.1   0.0    2.5  3  TAXi_C    Xylanase inhibitor C-terminal
  ------ inclusion threshold ------
      0.012   15.8   0.4        1.3    9.2   0.0    2.6  3  TAXi_N    Xylanase inhibitor N-terminal
       0.19   11.3   0.0       0.33   10.5   0.0    1.4  1  BCLP      Beta-casein like protein


Domain annotation for each model (and alignments):
>> Asp  Eukaryotic aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  164.9   0.2   6.5e-52   2.9e-48       2     314 ..      84     410 ..      83     411 .. 0.89

  Alignments for each domain:
  == domain 1  score: 164.9 bits;  conditional E-value: 6.5e-52
                 EEEEEEETTTTEEEEEEEETT--SEEEEBTTESTSHCHHTSS-B-GGG-.TT-EEEEEEEEEECTTS.E.......EEEEEEEEEEEETTEEEEEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxx.x.......xxxxxxxxxxxxxxxxxxxxxxx RF
         Asp   2 YfgeisiGtpeqkftvifDTGSsdlWVpsskckkssackshstydpskS.stykkngkslsisYGdg.s.......vsGflsqdtvkvggltvknqefg 91 
                 +++++ iGtp+q++ +i+D GS dl V s++++ s    + ++y+p kS s++k +g+s++i YG+g +        sG ++ d v++gg+t + q+++
  EEA19893.1  84 WISTVLIGTPPQELDLILDSGSWDLIVYSTQSDPSDLPANITLYNPDKSlSSRKLEGYSFDIIYGNGdTetegdieCSGDVFLDVVTIGGVTAPSQAVE 182
                 57899*****************************999**********99677889*********987533333333579999***************** PP

                 EEEEESSHHHTTSSSSEEEE-S-GGGSCGG...SCCHHHHHHHTTSSSSSEEEEEE-STTSSEEEEEESSEEGGGEEEEEEEEEESS....TSSTEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxx RF
         Asp  92 eatkepgstflaakfdGiLGlgfkeisvee...atpvfdnlvsqglikepvfsvylnreeeeggeivfGgvDeskykGsltyvpvts....kgywqiel 183
                 +  + ++ +++ a   Gi+G++++++++++   ++++f+ ++++  +++p+f   l    ++ +++ fG++++s ++G +t+ +v++    +g+w+i++
  EEA19893.1 183 SIVNYTSGFATLA-ATGIVGMALSKNNTVKplkQQTFFSSIKHE--LEKPLFVADLY--LKADSHLDFGYLNKSLIEGPVTWADVDTddsqQGWWSITI 276
                 9998888655555.99************9999888889998887..9*****98885..78999*********************99898899****** PP

                 EEEEETTEEEEEEEEEEEEEETTCSSEEEEHHHHHHHHHHHTTEEEETT.CEEEEETTGGGGSEEEEEEETTEEEEEEGGGGEEEESSSTTSEEEESE. CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx. RF
         Asp 184 esvtvggktvlcssgcqailDtGTsllalptsivekiakaigakksese.geyvvdCdslsslpdisftiggakitvpvselvlkeeeseesqCilgl. 280
                 + ++vg+++   + ++q i+DtGT+ l ++++iv ++ +++ ++ +++e   +++ Cds  +lpd+++ti+g+ +t+p s l l+  +s  ++C+ ++ 
  EEA19893.1 277 DAYQVGSEKP-VEGEFQTIIDTGTTNLLFQNDIVGAYYDQVPGSVNSTEfAAFLIPCDS--HLPDFTVTISGRPFTIPGSLLNLEAINS--TTCVGNIq 370
                 ********99.99****************************9987766426789****7..************************9975..68****98 PP

                 ......EECCTSSSEEEEHHHHTTEEEEEETTTTEEEEEE CS
                 ......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp 281 ......vseeegdlwiLGdvFlrsayvvfdldnnrvglAe 314
                       +    ++   LG +F+  + + fdl+  rvg+A+
  EEA19893.1 371 vvpastIGGIVQPNACLGATFMLPYLTAFDLGSLRVGFAQ 410
                 8665544445678999***********************8 PP

>> TAXi_C  Xylanase inhibitor C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0      0.87   3.9e+03      20      49 ..     189     218 ..     182     230 .. 0.71
   2 ?    1.5   0.0     0.051   2.3e+02      28      49 ..     288     309 ..     273     329 .. 0.77
   3 !   12.1   0.0   2.9e-05      0.13      90     160 ..     334     409 ..     329     410 .. 0.93

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.87
                 ----EE-S----SEEE-SSSSSEEE-HHHH CS
      TAXi_C  20 asaldldktgsggtvlstgtpytvletdvY 49 
                 ++  +l++tg  g+ ls  +++  l+++ +
  EEA19893.1 189 SGFATLAATGIVGMALSKNNTVKPLKQQTF 218
                 555566899999999999998888877654 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.051
                 ----SEEE-SSSSSEEE-HHHH CS
      TAXi_C  28 tgsggtvlstgtpytvletdvY 49 
                 +g+ +t+++tgt+   +++d+ 
  EEA19893.1 288 EGEFQTIIDTGTTNLLFQNDIV 309
                 68899********999999885 PP

  == domain 3  score: 12.1 bits;  conditional E-value: 2.9e-05
                 S----EEEEESSS-EEEE-GGGGEEE-SSSEEEE-EEE-......-S--SSSEEE-HHHHBTS-EEEETTTTEEEEE CS
      TAXi_C  90 pavPtitlvleggaewtisgenllvkveggvvClafves......gvagesavviGglqlednllvFDleksrlgFs 160
                 +++P++t+    g+ +ti+g+ l +++ ++++C++ ++       g   ++++ +G+  +  +l  FDl + r+gF+
  EEA19893.1 334 SHLPDFTVTIS-GRPFTIPGSLLNLEAINSTTCVGNIQVvpastiGGIVQPNACLGATFMLPYLTAFDLGSLRVGFA 409
                 57899999999.89*********************99999999998889999************************8 PP

>> TAXi_N  Xylanase inhibitor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.0   0.00029       1.3       3      52 ..      86     136 ..      84     144 .. 0.69
   2 ?    4.1   0.1     0.011        48      91     154 ..     159     218 ..     135     229 .. 0.71
   3 ?   -2.8   0.0       1.4   6.4e+03      13      33 ..     290     310 ..     282     335 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00029
      TAXi_N   3 vsisiGtppqplklvvDtGs.dltWvqCkpckacssqkkpvfdpsksstyk 52 
                  ++ iGtppq+l l++D Gs dl+    +   +  + + ++++p ks +++
  EEA19893.1  86 STVLIGTPPQELDLILDSGSwDLIVYSTQSDPSDLPANITLYNPDKSLSSR 136
                 5789****************4444433333333466666666666666665 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.011
      TAXi_N  91 sssGvlatdtltlsstdgksvkvp.nlvfGCgksnlgglaa.gadGilGLGrgklSlvsqlaskgs 154
                 + sG++  d++t+     ++v+ p + v + ++  ++g+a+  a+Gi+G++ +k   v+ l++++ 
  EEA19893.1 159 ECSGDVFLDVVTI-----GGVTAPsQAVESIVN-YTSGFATlAATGIVGMALSKNNTVKPLKQQTF 218
                 5577888888888.....555555333334444.4555555379**************99998853 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 1.4
      TAXi_N  13 plklvvDtGsdltWvqCkpck 33 
                 +++ ++DtG   + +q +   
  EEA19893.1 290 EFQTIIDTGTTNLLFQNDIVG 310
                 577899999888877765554 PP

>> BCLP  Beta-casein like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   7.5e-05      0.33      33      86 ..     172     226 ..     160     239 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 7.5e-05
        BCLP  33 kkavtleyavsnviavvsgllsi.isGivaivlsrnlknkklqwallvlsllaal 86 
                    ++ + av +++  +sg+ +  ++Giv + ls+n + k+l+   + +s+   l
  EEA19893.1 172 GGVTAPSQAVESIVNYTSGFATLaATGIVGMALSKNNTVKPLKQQTFFSSIKHEL 226
                 5566778899**********987368******************99999987665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (420 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       384  (0.0214178); expected 358.6 (0.02)
Passed bias filter:                      339  (0.0189079); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.44
# Mc/sec: 2861.61
//
Query:       EEA19894.1  [L=256]
Description: 3-hydroxyacyl-CoA dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.7e-23   82.0   0.0    7.5e-15   54.9   0.0    2.1  2  adh_short        short chain dehydrogenase
    1.6e-22   80.2   0.1    1.1e-14   54.6   0.0    2.1  2  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
  ------ inclusion threshold ------
      0.064   13.1   0.0        2.1    8.2   0.0    2.1  2  Ligase_CoA       CoA-ligase
       0.12   12.7   0.0       0.19   12.0   0.0    1.3  1  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   0.0   2.1e-09   9.3e-06       6      63 ..      18      77 ..      16      82 .. 0.95
   2 !   54.9   0.0   1.7e-18   7.5e-15     103     191 ..      82     177 ..      78     180 .. 0.89

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 2.1e-09
                ESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT..TSEEEEEE-TTTSHHH CS
   adh_short  6 tGassGIGraiakelakeGakvvvvdrseekleevakelkee..gakalaiqvDvtdree 63
                +G+++GIGr++++ +++ Ga v + d+ e++ + + + ++++  + +a +++vDvt++++
  EEA19894.1 18 IGGARGIGRNLVELCVQHGAYVCFGDIDEKAGHDIQEAINADrdSPSAKFVRVDVTNYQS 77
                69***************************************999999*********9987 PP

  == domain 2  score: 54.9 bits;  conditional E-value: 1.7e-18
                 HHHHHHTHHHHHHHHHHHHHHH....HCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHG..GGT.EEEEEEEESSBSSHHHHHHC CS
   adh_short 103 rvievNltgvflltravlpaml....kqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakela..ptg.irvnavaPGlvdTdmakelr 191
                  v++vNl g + ++r +  ++     +++  +   vsSvag+++++g+  Y AsK++v gl+rsl+k ++  +t+ irvna++P +++T+m++ ++
  EEA19894.1  82 TVLDVNLLGCIYCARIASVYLRqnrsENQDRSLTLVSSVAGFKESPGLFLYQASKHGVLGLMRSLRKYISlpTTNnIRVNAICPWMTETGMVAGIE 177
                 589*****************998888888889**********************************9875323446***************98776 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.0   5.7e-09   2.6e-05       1      55 [.      19      77 ..      19      82 .. 0.78
   2 !   54.6   0.0   2.5e-18   1.1e-14      97     232 ..      82     216 ..      80     218 .. 0.88

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 5.7e-09
                  TTTTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHH.HTT...SEEEE--TTSHHH CS
  adh_short_C2  1 GaasgIGraiAkalaeeGaevvltdlneeakkrveelae.elg...aevlecDVtdeeq 55
                  G a+gIGr +++++ ++Ga v++ d++e+a ++++e+ + + +   a+++++DVt+ ++
    EEA19894.1 19 GGARGIGRNLVELCVQHGAYVCFGDIDEKAGHDIQEAINaDRDspsAKFVRVDVTNYQS 77
                  669***************************5555555540444332336******9876 PP

  == domain 2  score: 54.6 bits;  conditional E-value: 2.5e-18
                   HHHHHHTHHHHHHHHHHHHHCTSC......CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGG...GTEEEEEEEE--BHCTGGGGSTT CS
  adh_short_C2  97 raldvnlyslfllakaalplmkeg......gsivnlssvgaervvpnynaygaaKaalealtrylAvelgp...kgiRvNavspgpikTlaasgikg 184
                   ++ldvnl +++++a+ a  +++++       s+  +ssv++ +  p+   y+a+K+++ +l+r+l + +     ++iRvNa++p +++T +++gi+ 
    EEA19894.1  82 TVLDVNLLGCIYCARIASVYLRQNrsenqdRSLTLVSSVAGFKESPGLFLYQASKHGVLGLMRSLRKYISLpttNNIRVNAICPWMTETGMVAGIE- 177
                   689***************977766678888899999*****************************8776533349********************8. PP

                   HHHHHHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEESTT CS
  adh_short_C2 185 fdelleelearaplgrlgtpeevaeaalfLasdeasyitGqtlvvDgG 232
                       + + +a+ p ++   p +va++++  +sd   + +G+ ++v gG
    EEA19894.1 178 ----EGWRKANLPTNQ---PLDVAKVIAGVVSDP--GLNGTSMYVEGG 216
                   ....445566677776...9************97..9**********9 PP

>> Ligase_CoA  CoA-ligase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   0.0   0.00046       2.1      65     123 ..      72     128 ..      65     137 .. 0.82
   2 ?    2.8   0.0     0.021        95      64     123 ..     145     205 ..     141     214 .. 0.89

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.00046
                 HHHHHS-TT-SEEEEEEEESSSEHHHHHHHHHHHHHHTT...--S-EEEEEECTTHH.. CS
  Ligase_CoA  65 lkklaadpevkvilldivlGygahedpaaellkaikeakaegrelpvvarvaGteadpq 123
                 ++++++ p + v+ +++ lG   ++ +a+ +l++ ++ + + r l +v++vaG ++ p+
  EEA19894.1  72 VTNYQSAPPTTVLDVNL-LGCIYCARIASVYLRQNRSEN-QDRSLTLVSSVAGFKESPG 128
                 56677777777777765.7889************99987.9************998876 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.021
                 HHHHHHS-TT-SEEEEEEEESSSEHHHHHHHHHHHHHHTT....--S-EEEEEECTTHH.. CS
  Ligase_CoA  64 alkklaadpevkvilldivlGygahedpaaellkaikeaka.egrelpvvarvaGteadpq 123
                  l+k+ + p+++ i ++ +  +++++ ++a++ + +++a+  ++++l v   +aG   dp+
  EEA19894.1 145 SLRKYISLPTTNNIRVNAICPWMTETGMVAGIEEGWRKANLpTNQPLDVAKVIAGVVSDPG 205
                 688999999******************************8888888888889999999975 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   4.3e-05      0.19       6      61 ..      20      77 ..      16     103 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 4.3e-05
                     -.SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHH....TTTCEEEEE--TTTHHH CS
  Sacchrp_dh_NADP  6 a.GsvGqavaellarhfdvdaeitvadrskeklealaaka....lgvrfeaialdaenyea 61
                     +  ++G+ ++el+++h+ +   ++  d +++  + + +++     +++++++ +d+ ny++
       EEA19894.1 20 GaRGIGRNLVELCVQHGAY---VCFGDIDEKAGHDIQEAInadrDSPSAKFVRVDVTNYQS 77
                     4479*************99...88888888887777766699999**************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (256 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       400  (0.0223102); expected 358.6 (0.02)
Passed bias filter:                      387  (0.0215851); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 1847.96
//
Query:       EEA19895.1  [L=177]
Description: metallo-beta-lactamase domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.1e-14   54.0   0.7      4e-14   53.1   0.7    1.4  1  Lactamase_B      Metallo-beta-lactamase superfamily
     0.0024   17.4   0.0     0.0025   17.4   0.0    1.2  1  Lactamase_B_2    Beta-lactamase superfamily domain
  ------ inclusion threshold ------
      0.035   13.9   0.0      0.047   13.5   0.0    1.2  1  N6-adenineMlase  Probable N6-adenine methyltransferase


Domain annotation for each model (and alignments):
>> Lactamase_B  Metallo-beta-lactamase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.1   0.7   6.7e-18     4e-14       5     158 ..      16     175 ..      13     177 .] 0.87

  Alignments for each domain:
  == domain 1  score: 53.1 bits;  conditional E-value: 6.7e-18
                  SSEEEEEEETTCEEEES-..-SCHHHHHHHHHHHHHTSGGGGEEEEE-SBSSHHHHTTGGGCTTHHCCEETCCEHHHHCCHCHHHHHHHHHCCHH... CS
  Lactamase_B   5 pvnsyliegdggviLiDt..GtsteaaraalelaalglkpkdvdavilTHlHlDHiGglgglveatdvpvgavaeeapalfmeeaddaasrkgll... 97 
                  ++ + li g ++++L+D+  +++ +++   + +++    +  ++av++TH+H+DH++ ++ + ea++ +++  a +  a++++e dd   +++++   
   EEA19895.1  16 SSVTSLIIGTKEAVLFDPpfLIPDANDTVTW-IKKTLMADHTLKAVFVTHHHPDHFFSANPILEAFPEASFFAAPYVLAGINREYDDKVNYWPSIfgr 112
                  5666777789999999987777777777777.8999999999******************************************************99 PP

                  ..TTCHCGCCEEEEETTTEECCCTEEEEEHECTTSTSCCEEEEEETTCCEEEECTTTSSHHCC CS
  Lactamase_B  98 ..lagvsadkpdvdeeeldgnaggrralyvtggpghghghgvveygggkvlftGDallagetg 158
                    ++  ++++p + +    ++ ++ +     + +g + +h +++++ +++l++GD++++++ +
   EEA19895.1 113 enIPLQPRKDPFEYTFFVLDGNPESPVHLLGPVQGDSVDHTIFWLPKERTLICGDTVYRPSPP 175
                  99777777777777777777777888888899999999********************99876 PP

>> Lactamase_B_2  Beta-lactamase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.0   4.2e-07    0.0025      29      75 ..      55     100 ..      29     173 .. 0.74

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 4.2e-07
                    .SEEEEE-SS--HHHHGGGGCCCC.C--EEEEEEEEHHHHHHCCTTCG CS
  Lactamase_B_2  29 ppidaVllthaHyDHlaglltlre.lrpkklplyapkgvlavleanfv 75 
                    + ++aV++th H DH+  +  + e +   ++ ++a + vla ++++ +
     EEA19895.1  55 HTLKAVFVTHHHPDHFFSANPILEaFP--EASFFAAPYVLAGINREYD 100
                    479*************65666666253..4789999999998887755 PP

>> N6-adenineMlase  Probable N6-adenine methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   7.9e-06     0.047      86     122 ..      23      63 ..       5      84 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 7.9e-06
  N6-adenineMlase  86 kgkfdviviDPPFlseeclkklaktaklllk....klilct 122
                       g+ + +++DPPFl  +   +++ + k+l++    k +++t
       EEA19895.1  23 IGTKEAVLFDPPFLIPDANDTVTWIKKTLMAdhtlKAVFVT 63 
                      577889***************99999999888777666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (177 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       221  (0.0123264); expected 358.6 (0.02)
Passed bias filter:                      211  (0.0117686); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.40u 0.29s 00:00:00.69 Elapsed: 00:00:00.43
# Mc/sec: 1236.50
//
Query:       EEA19896.1  [L=621]
Description: pogo transposable element, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.5e-24   85.0   0.0    9.1e-24   84.1   0.0    1.5  1  DDE_1         DDE superfamily endonuclease
    8.9e-09   35.3   0.3    3.1e-08   33.5   0.3    2.0  1  HTH_Tnp_Tc5   Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
      0.024   14.8   0.1       0.53   10.5   0.0    2.7  3  Pcc1          Transcription factor Pcc1
      0.066   12.2   1.4        0.1   11.6   1.4    1.2  1  Amidase       Amidase


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.1   0.0     2e-27   9.1e-24       2     175 .]     193     368 ..     192     368 .. 0.89

  Alignments for each domain:
  == domain 1  score: 84.1 bits;  conditional E-value: 2e-27
       DDE_1   2 erltvllcanaagsekLkplvigkak..sprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrleaekrk..ilLlldssrshetvel.le 94 
                 +++ ++++++ a++  + p +i+ ak  +++ ++    ++++  + +  ++ +w+ ++++ +WL +vfdk ++++ ++   lL+ld+++sh t+ + + 
  EEA19896.1 193 REWITTIGCICANGTAISPALIYMAKsgNLQDSWLQDFDAEQHRCFFATSESGWTNNEVGFAWLvNVFDKETKSQASRgwRLLILDGHGSHVTMRFiEY 291
                 678999****************9665226888999999***********************************666652267**************999 PP

       DDE_1  95 selqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                 ++++ i l+++Pa+s+++lqPld+ ++s+l + Y +ql + +++  +        lt +d+++   ++w+  +++e+i saf
  EEA19896.1 292 CDKNRILLAIFPAHSTHTLQPLDVAIFSPLSTAYTEQL-RRFINDCQGFTR----LTKRDFFRLFWASWEaTFTSENILSAF 368
                 **********************************8765.556666655555....9**************99******9987 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.5   0.3     7e-12   3.1e-08       2      60 ..      59     108 ..      58     115 .. 0.91

  Alignments for each domain:
  == domain 1  score: 33.5 bits;  conditional E-value: 7e-12
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh 60 
                  +e+ + L++Wi+ql+erg p+t++++ + A+e+         + + ++k+W  r++k h
   EEA19896.1  59 KEQSRTLIKWINQLTERGLPPTNSMLENFAREI---------SGKEPGKNWASRWLKAH 108
                  68999****************************.........67889**********99 PP

>> Pcc1  Transcription factor Pcc1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00012      0.53      12      50 ..       5      43 ..       1      59 [. 0.88
   2 ?    0.7   0.0      0.13   5.8e+02      49      66 ..     405     422 ..     402     423 .. 0.91
   3 ?   -2.5   0.1       1.3   5.9e+03      12      37 ..     556     584 ..     553     609 .. 0.58

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00012
                HHHHHHHHHHHHHCHC-TTECEEEEEEETTEEEEEEEES CS
        Pcc1 12 rlAsialrtLqvDkelsplavkrslslegnvLqveykAt 50
                +lA  alr+L++D++++ + v r++ ++++ L  +++  
  EEA19896.1  5 ELALEALRSLKPDEKPNISLVARTYGVNQSNLSKRFRGV 43
                78888********9999888***********99998875 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.13
                 ESSHHHHHHHHHHHHHHH CS
        Pcc1  49 AttnrmLRvavngflesl 66 
                 A++ r LR  v+g++e+l
  EEA19896.1 405 AEDWRRLRKLVQGVFEDL 422
                 9999************98 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 1.3
                 HHHHHHHHHHHHH..CHC-TTE.CEEEEE CS
        Pcc1  12 rlAsialrtLqvD..kelspla.vkrsls 37 
                 +lA+ a   Lq D  + +s ++  k+++s
  EEA19896.1 556 ELAKLAHLQLQNDvlATPSAPKrAKKQVS 584
                 67888888888886544444444444443 PP

>> Amidase  Amidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   1.4   2.2e-05       0.1     309     395 ..     498     588 ..     470     611 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 2.2e-05
                 ---SS-SCCCCCCCHHHHCCS-HHHHHHHHHHHHHCSCCCCCCCHHHHHHHHH.HHHHHHHHHCCC...BSEEEEESSSSS--BCCCCCHH CS
     Amidase 309 erlsetkvlsellpksraellgeevkrrielgnyalsaeasskyylkaqkvrr.llrrefakafee...lDvllsPtaptpaprlgekdkt 395
                 +  + ++  +++  k+ +++l+++ k + +    ++ +e++++ +++a++ +r   ++e+ak+ +     Dvl++P+ap+ a+++  k+ +
  EEA19896.1 498 KDEQAAQEQARKDDKKLQQELTKQAKEQEKAERAQIRQEKQEQRLQEATEKQRlKDEQELAKLAHLqlqNDVLATPSAPKRAKKQVSKQVK 588
                 2333344445666667777777777777777777777777777777777666656667777765557778*************99888754 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (621 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3079  (0.171733); expected 358.6 (0.02)
Passed bias filter:                      875  (0.0488036); expected 358.6 (0.02)
Passed Vit filter:                       171  (0.00953762); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.91u 0.32s 00:00:01.23 Elapsed: 00:00:00.50
# Mc/sec: 3770.92
//
Query:       EEA19897.1  [L=132]
Description: hypothetical protein PMAA_006640 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.065   13.4   0.5       0.14   12.3   0.1    1.8  2  DUF596    Protein of unknown function, DUF596


Domain annotation for each model (and alignments):
>> DUF596  Protein of unknown function, DUF596
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.1     8e-06      0.14      17      39 ..      72      94 ..      58     111 .. 0.80
   2 ?   -1.5   0.1      0.16   2.8e+03      42      49 ..     124     131 ..     107     132 .] 0.63

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 8e-06
                --HHHHHHHHHHH--SSSEE--T CS
      DUF596 17 GtteelvemfrksfPesdeeldl 39
                 t  el e f++sfPe +++ld+
  EEA19897.1 72 ATVDELYEFFKNSFPEANKNLDF 94
                4789****************995 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.16
                 EE.HHHHH CS
      DUF596  42 vdaeglWf 49 
                    +g+Wf
  EEA19897.1 124 QSLQGYWF 131
                 34579998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (132 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       568  (0.0316805); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.24s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 973.94
//
Query:       EEA19898.1  [L=804]
Description: 6-phosphofructokinase alpha subunit [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   3.3e-192  637.0   0.7     2e-105  352.2   0.1    2.1  2  PFK       Phosphofructokinase
  ------ inclusion threshold ------
      0.017   14.7   0.1      0.081   12.6   0.1    2.2  2  DAGK_cat  Diacylglycerol kinase catalytic domain


Domain annotation for each model (and alignments):
>> PFK  Phosphofructokinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  352.2   0.1  2.3e-109    2e-105       1     283 [.      27     333 ..      27     334 .. 0.97
   2 !  283.5   0.1   1.9e-88   1.7e-84       1     283 [.     415     710 ..     415     711 .. 0.91

  Alignments for each domain:
  == domain 1  score: 352.2 bits;  conditional E-value: 2.3e-109
                 EEEEEEESS--TTHHHHHHHHHHHHHHTT-EEEEETTHHHHHHTT..-EEEE-SGGGTT-TT--S-TT-----GGGGSHHHHHHHHHHHHHHT--EEEE CS
         PFK   1 riailtsGGdapGmNaairavvrtaikkglevygireGfeGliee..eiekltledvsgilsegGtiLgsaRskefkeregrkkaaenlkklgidaLvv 97 
                 ria+ltsGGdapGmN a+ravvr+ai++g+e ++++eG+eGl+ +   i+++++edv+g+ls gGt +gsaRs +f+er gr +aa+n++ +gidaLvv
  EEA19898.1  27 RIAVLTSGGDAPGMNGAVRAVVRMAIHSGCEAFAVHEGYEGLVAGgdFIKQMHWEDVRGWLSLGGTRIGSARSMKFRERAGRLEAAKNMVLKGIDALVV 125
                 7******************************************99866679************************************************ PP

                 EESHHHHHHHHHHHHT..T.....................--EEEEEEETT---TT-S--EEHHHHHHHHHHHHHHHHHHHHHHT-EEEEEES-TT-TH CS
         PFK  98 iGGdgslkganklseerkgllee.................lkivgiPkTidNDipgtdytiGfdTAlntiveaidklkstakshkrvfvvEvmGrncGw 179
                 +GGdgsl+ga+ +++e++gll+e                 l+ivg++++idND+ gtd tiG++++l++i++a+d++ +ta+sh+r fv+EvmGr+cGw
  EEA19898.1 126 CGGDGSLTGADLFRSEWPGLLKElvqvgqlteeqvfpyttLNIVGLVGSIDNDLSGTDATIGCYSSLTRICDAVDDVFDTASSHQRGFVIEVMGRHCGW 224
                 *********************99**************************************************************************** PP

                 HHHHHHHHHT-SEEE-TTS---HH...HHHHHHHHHHT.T-S-EEEEEESSS..S-.....HHHHHHHHHHHHSS-EEEEE-GGGGG-S---HHHHHHH CS
         PFK 180 lAlmaglaggadvilipEepfdie...eliekikklrkkgkkksiivvaEgakdkeg..iiaeelakeieektgievrvtvlGhlqrGgspsafDrila 273
                 lAlma++++gad+++ipE p+      +++++i+k r++gk+++i++vaEga+d++   i+++ +++++++++g+++rvtvlGh+qrGg+++a+Dr+l+
  EEA19898.1 225 LALMAAISTGADWVFIPEMPPRDGwedDMCASITKTRERGKRRTIVIVAEGAQDRQLnkISSNAVKDLLSNRLGLDTRVTVLGHTQRGGPACAYDRWLS 323
                 *******************99744778**************************76557799************************************** PP

                 HHHHHHHHHH CS
         PFK 274 trlGikavel 283
                 t+ G++av++
  EEA19898.1 324 TLQGVEAVKA 333
                 ********97 PP

  == domain 2  score: 283.5 bits;  conditional E-value: 1.9e-88
                 EEEEEEESS--TTHHHHHHHHHHHHHHTT-EEEEETTHHHHHHTT.......-EEEE-SGGGTT-TT--S-TT-----GGGGSHHHHHHHHHHHHHHT- CS
         PFK   1 riailtsGGdapGmNaairavvrtaikkglevygireGfeGliee.......eiekltledvsgilsegGtiLgsaRskefkeregrkkaaenlkklgi 92 
                 riai+++G++a GmN a+ra+v +++++g++ +++++Gf Gl+++       +++++t+ + +++ +egG+ +g++R  +    e++++ a+ ++k+++
  EEA19898.1 415 RIAIIHVGAPAGGMNPATRAAVGYCLTRGHKAIAVHNGFPGLCRHyddkpisSVREITWLESDDWVNEGGSEIGTNRGLPG---EDLEATARAFEKHKF 510
                 7*****************************************7765556655677999**********************6...459************ PP

                 -EEEEEESHHHHHHHHHHHHT..T.....--EEEEEEETT---TT-S--EEHHHHHHHHHHHHHHHHHHHHHH.T-EEEEEES-TT-THHHHHHHHHHT CS
         PFK  93 daLvviGGdgslkganklseerkgllee.lkivgiPkTidNDipgtdytiGfdTAlntiveaidklkstaksh.krvfvvEvmGrncGwlAlmaglagg 189
                 daL++iGG++++++a++l++ r+ ++++ ++iv++P+Ti+N++pgt+y++G+dT+lnt++  +d+++++a+s+ +rvfvvE++G+++G++A+ agla g
  EEA19898.1 511 DALFIIGGFEAFTAASQLRKGREFYSAFkIPIVVLPATISNNVPGTEYSLGSDTCLNTLIMFCDAIRQSASSSrRRVFVVETQGGKSGYIATTAGLAIG 609
                 *******************9986666557********************************************9************************* PP

                 -SEEE-TTS---HHHHHHHHHHHH.....T.T-S-E..EEEEESSS..S-...HHHHHHHH.HHHHSS.-EEEEE-GGGGG-S---HHHHHHHHHHHHH CS
         PFK 190 advilipEepfdieeliekikklr.....kkgkkks..iivvaEgakdkegiiaeelakei.eektgi.evrvtvlGhlqrGgspsafDrilatrlGik 279
                 a +++ipEe ++i+ l+++i+ lr     ++g +++  ii+++E a++   ++++ +a++i ee+ g  e+r++v+Gh q+Gg+ps++Dri a r++ik
  EEA19898.1 610 AAAVYIPEEGINIKMLSQDIEFLRasftaDRGANRAgkIILRNETASQ--TYTTQVIADMIkEEARGRfESRAAVPGHFQQGGKPSPMDRIRALRMAIK 706
                 ************************88876334333366********86..5689999999954444435****************************** PP

                 HHHH CS
         PFK 280 avel 283
                 ++++
  EEA19898.1 707 CMQH 710
                 *986 PP

>> DAGK_cat  Diacylglycerol kinase catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.1     9e-06     0.081      38      68 ..     102     132 ..      69     135 .. 0.78
   2 ?   -2.6   0.0      0.45     4e+03      44      64 ..     498     518 ..     493     547 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 9e-06
                 --STTHHHHHHHHHHHCC-SEEEEEESHHHH CS
    DAGK_cat  38 teepgdakelakeakeegvdlivvaGGDGtv 68 
                   e+    e ak++  +g+d++vv+GGDG +
  EEA19898.1 102 FRERAGRLEAAKNMVLKGIDALVVCGGDGSL 132
                 445555678999*****************87 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 0.45
                 HHHHHHHHHHCC-SEEEEEES CS
    DAGK_cat  44 akelakeakeegvdlivvaGG 64 
                  ++ a+  +++++d+++++GG
  EEA19898.1 498 LEATARAFEKHKFDALFIIGG 518
                 566788888889999999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (804 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       475  (0.0264934); expected 358.6 (0.02)
Passed bias filter:                      454  (0.0253221); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.87u 0.33s 00:00:01.20 Elapsed: 00:00:00.58
# Mc/sec: 4146.29
//
Query:       EEA19899.1  [L=295]
Description: cell wall integrity and stress response component 1 precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      1e-05   24.6  10.1    1.6e-05   24.0  10.1    1.2  1  VSP           Giardia variant-specific surface protein
    0.00023   21.3  10.5    0.00042   20.5  10.5    1.4  1  Podoplanin    Podoplanin
     0.0015   18.3   0.1     0.0023   17.7   0.1    1.3  1  DUF4448       Protein of unknown function (DUF4448)
     0.0049   16.3   2.1     0.0049   16.3   2.1    2.1  2  SKG6          Transmembrane alpha-helix domain
  ------ inclusion threshold ------
      0.025   13.6  33.6      0.032   13.2  33.6    1.1  1  DUF5585       Family of unknown function (DUF5585)
      0.026   14.5  32.2      0.042   13.8  32.2    1.3  1  Mucin         Mucin-like glycoprotein
       0.16   12.1  17.2       0.33   11.2  17.2    1.5  1  AJAP1_PANP_C  AJAP1/PANP C-terminus
       0.66    9.8   2.5        1.5    8.7   0.4    2.3  2  LapA_dom      Lipopolysaccharide assembly protein A domain


Domain annotation for each model (and alignments):
>> VSP  Giardia variant-specific surface protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.0  10.1   6.9e-09   1.6e-05     274     390 ..     106     225 ..      73     229 .. 0.51

  Alignments for each domain:
  == domain 1  score: 24.0 bits;  conditional E-value: 6.9e-09
         VSP 274 tcldGyvks.sdacakc.dsscetctGaattcktcatG..yyksatkevactssesdkgvtGvkdclscappssdkGsvlcylikdsgstnksGlstGa 368
                   + G+  + + + ++  +++  t + ++tt  t ++      s+t+ ++ t++ s  + t  +   s a  +s    +   l     ++  sGls+Ga
  EEA19899.1 106 PTTWGQSAAaAWSSSLAaAATATTSSSSSTTISTSTSTtsSSISTTAATSSTTTASSATTTSATTLTSAATITSAAPQIATPLS---TAVSSSGLSSGA 201
                 444444443222222220222333333333333322220022222223333333333444555554555555555555555554...46889******* PP

         VSP 369 iaGisvavvvvvgGlvG..flcww 390
                 iaGi+v +v+ v  l+G   + ww
  EEA19899.1 202 IAGIAVGAVIGVVALLGmgIFFWW 225
                 ********9998888762156777 PP

>> Podoplanin  Podoplanin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5  10.5   1.9e-07   0.00042      55     147 ..     125     218 ..      95     227 .. 0.61

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 1.9e-07
                 XXXXXXXXXXXXXXXXXXXX-----GGG-XXXXXXXXXXXXXXXXXX.XXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Podoplanin  55 aseepyesglttlvptstesvtdlrledlptaestvkakeesqsttt.lnvvtshst.ekvgeetettvekdGLatvtLvgiivGvllaigfigg 147
                 a+   ++s+ +t ++tst  +++      +t+ +t++   ++ s+tt ++++t +s   ++    +t+v   GL+  ++ gi vG ++++  + g
  EEA19899.1 125 ATAT-TSSSSSTTISTSTSTTSSSISTTAATSSTTTASSATTTSATTlTSAATITSAaPQIATPLSTAVSSSGLSSGAIAGIAVGAVIGVVALLG 218
                 2222.223333346666655555555555555555555555555555233444444357889999********************9998754443 PP

>> DUF4448  Protein of unknown function (DUF4448)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.1     1e-06    0.0023      76     186 ..      83     229 ..      44     232 .. 0.57

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 1e-06
     DUF4448  76 k.............ksffssdwlpnsdGfypltvdeewlkgkkser......vti.vlvslqpdnvkd.................eveikkGpkVsltk 137
                               + ++++++ p ++G  +    ++ l    + +      +ti + +s++++++++                  +++++        
  EEA19899.1  83 LddgstvlylscffNVAHNTSQSPTTWGQSAAAAWSSSLAAAATATtsssssTTIsTSTSTTSSSISTtaatsstttassatttsATTLTSA------- 174
                 24555555555555555555556666665555555555555322221111113333333333333322444443333233333333333333....... PP

     DUF4448 138 kedlk..........kledkeseegkkaekyalaialPvvvvvlvlgligfvlwnrkkr 186
                     +          +  +++++++  +++++  ia+  v++v++l+ +g+++w+r+++
  EEA19899.1 175 ----AtitsaapqiaTPLSTAVSSSGLSSGAIAGIAVGAVIGVVALLGMGIFFWWRNRN 229
                 ....144555565666668899*******************999999999999988764 PP

>> SKG6  Transmembrane alpha-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.4   1.1         6   1.3e+04       2       9 ..     129     136 ..     128     137 .. 0.48
   2 !   16.3   2.1   2.2e-06    0.0049       2      38 .]     193     229 ..     192     229 .. 0.82

  Alignments for each domain:
  == domain 1  score: -4.4 bits;  conditional E-value: 6
        SKG6   2 sdssnsnt 9  
                 ++ss+s+t
  EEA19899.1 129 TSSSSSTT 136
                 55444443 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 2.2e-06
        SKG6   2 sdssnsntvaIavaVaVPVaViiivLlailifvrRRk 38 
                 s+s++s+++  ++aV+  ++V++++  +i++++r R+
  EEA19899.1 193 SSSGLSSGAIAGIAVGAVIGVVALLGMGIFFWWRNRN 229
                 6778888888889999888999999999999999886 PP

>> DUF5585  Family of unknown function (DUF5585)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2  33.6   1.4e-05     0.032      87     202 ..     101     210 ..      90     257 .. 0.60

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.4e-05
     DUF5585  87 tdvsePvtsegaadgvassalttaasstsssaassaPttvasstslsapraevsrtnasvsartaiassvaaassiPttaassavstlvpvsgtvtsav 185
                      P+t + +a ++ ss l++aa++t+ss      tt+++st  s+  +++s+t+a++s+ ta ++++++a++   +a+ ++++  + +++ +t+  
  EEA19899.1 101 NTSQSPTTWGQSAAAAWSSSLAAAATATTSSSS---STTISTST--STTSSSISTTAATSSTTTASSATTTSATTLTSAATITSAAPQI-ATPLSTAVS 193
                 444579999998888888888888877754444...45555554..4444444444444443333333333333222222222222222.444444444 PP

     DUF5585 186 atghPslstalaqvpss 202
                 ++g  s + a ++v+++
  EEA19899.1 194 SSGLSSGAIAGIAVGAV 210
                 44444444444444444 PP

>> Mucin  Mucin-like glycoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8  32.2   1.9e-05     0.042      15     106 ..      92     186 ..      87     217 .. 0.68

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.9e-05
       Mucin  15 LcCCasvCvtang....eGqsdaavveaaegqskltttttttkppttttttttasttittkttkattttttttttttateaPsdavttaeaPtttt 106
                 L C   v  + ++     Gqs aa+ +++ +    t+tt +  ++t +t t+t+s++i+t++++++ttt++++ttt+at   s a+ t+ aP   t
  EEA19899.1  92 LSCFFNVAHNTSQspttWGQSAAAAWSSSLAAA-ATATTSSSSSTTISTSTSTTSSSISTTAATSSTTTASSATTTSATTLTSAATITSAAPQIAT 186
                 555555555444422223455444444444433.35555666778888889999999999999999***999999999999999999999997654 PP

>> AJAP1_PANP_C  AJAP1/PANP C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2  17.2   0.00015      0.33      16     105 ..     119     217 ..     101     230 .. 0.52

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00015
  AJAP1_PANP_C  16 sktvpnitlstkasrtttvatttstttrltqrtltvvttpeprrlsttess.vse.......gkt.vkppkilgdtsGlavhqiititvslimviaa 103
                   s+ +  +t++t +s +tt++t+tstt+++ ++t ++  t+++   +tt+++  ++       + + ++p  +   +sGl+   i  i+v  ++ + a
    EEA19899.1 119 SSLAAAATATTSSSSSTTISTSTSTTSSSISTTAATSSTTTASSATTTSATtLTSaatitsaAPQiATPLSTAVSSSGLSSGAIAGIAVGAVIGVVA 215
                   4444555555555566666666666654444433333333222222222220222111111122202333444556689888888888877766666 PP

  AJAP1_PANP_C 104 li 105
                   l+
    EEA19899.1 216 LL 217
                   64 PP

>> LapA_dom  Lipopolysaccharide assembly protein A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.1      0.29   6.6e+02       2      10 ..      11      19 ..      10      28 .. 0.91
   2 ?    8.7   0.4   0.00069       1.5      28      52 ..     206     234 ..     194     239 .. 0.69

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.29
    LapA_dom  2 NtqpVtvnf 10
                N+q Vt+n+
  EEA19899.1 11 NSQDVTLNY 19
                9*******9 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.00069
    LapA_dom  28 giGallgwllsl....wsylrlrrelrrl 52 
                 ++Ga++g+++ l    ++++r+r ++++ 
  EEA19899.1 206 AVGAVIGVVALLgmgiFFWWRNRNANKSS 234
                 55555555555543337888999888865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (295 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2063  (0.115065); expected 358.6 (0.02)
Passed bias filter:                      649  (0.0361983); expected 358.6 (0.02)
Passed Vit filter:                       127  (0.0070835); expected 17.9 (0.001)
Passed Fwd filter:                        28  (0.00156172); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.89u 0.38s 00:00:01.27 Elapsed: 00:00:00.59
# Mc/sec: 1503.76
//
Query:       EEA19900.1  [L=336]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (336 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       621  (0.0346366); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.65u 0.34s 00:00:00.99 Elapsed: 00:00:00.56
# Mc/sec: 1805.95
//
Query:       EEA19901.1  [L=662]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.6e-135  451.8   0.2     2e-135  451.5   0.2    1.1  1  DUF2264   Uncharacterized protein conserved in bacteria (DUF2


Domain annotation for each model (and alignments):
>> DUF2264  Uncharacterized protein conserved in bacteria (DUF2264)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  451.5   0.2  1.1e-139    2e-135       1     352 [.      24     373 ..      24     374 .. 0.98

  Alignments for each domain:
  == domain 1  score: 451.5 bits;  conditional E-value: 1.1e-139
     DUF2264   1 tRadwvealeklldpllpylspgkarvklpgeegahfdekaaqlEgfaRplwglapllaggdeeteegklrerylkglaagtdpespeywgeiedldgQ 99 
                 +R++++++l++lldpl+p++sp karv++pg +g +fd++aa++Eg++Rplwgla+llagg++  +  ++++ +++g++ag+dp+speywg+ +d d Q
  EEA19901.1  24 DRESVQQLLRTLLDPLQPFFSPAKARVRVPGGTGVRFDQTAADVEGICRPLWGLAFLLAGGGS--Y--AHTDAWIEGIKAGMDPQSPEYWGNPRDND-Q 117
                 699*********************************************************999..6..79*************************88.* PP

     DUF2264 100 rlVeaaalalaLllapeqlwekldeeekenlvewLk.qlrekempdnNWllFrvlvelaLkkvgeeydeerleedlekleefylgdGwysDGpe..rql 195
                 r+Ve++ l++a+++ap q+w++++ee k+n+ +wL  ++++kemp++NWl+Frv+++l+Lk+++ +y+ee+l++d+++le fy++ Gw++DGpe  +q+
  EEA19901.1 118 RMVEMCPLGVAFAIAP-QFWQSISEEDKRNVEQWLGnSINTKEMPNTNWLWFRVFANLGLKMNNGKYSEEKLQQDIKHLEGFYRSGGWSNDGPEgiHQM 215
                 ****************.5*****************99********************************************************5559** PP

     DUF2264 196 DYYs.sfaiqlyqllylkllaaeedperaekfrerarrfaedferlfdadGaaipfGRSltYRfAaaaplwaaalla..elpaplspgqvrglllrvlr 291
                 DYYs sfaiq++ql+y+kl a +edp+ra++f+erar  a d++++fd++G+aipfGRS++YRfA+++ +w a+++a  elpapl++g+v+g++lr++r
  EEA19901.1 216 DYYSsSFAIQFLQLIYAKL-AGAEDPDRAKEFKERARLLALDLVHYFDEEGRAIPFGRSMIYRFAVVS-FWGALAYAdvELPAPLTWGMVKGIVLRHFR 312
                 *******************.89999*******************************************.********99******************** PP

     DUF2264 292 wwleskgafdedGlltlGfagpnmelaenYnspgSpYwalkaflaLalpadhpfWtaeeep 352
                 ww +++++++++G+lt+G+ +pnm++ae+YnspgSpYwa+ af++La+p++hpfWt+ee p
  EEA19901.1 313 WWQSQPQIWSSSGTLTIGYSYPNMYMAESYNSPGSPYWACVAFICLAVPQSHPFWTSEEMP 373
                 **********************************************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (662 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       404  (0.0225333); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.75u 0.34s 00:00:01.09 Elapsed: 00:00:00.54
# Mc/sec: 3686.95
//
Query:       EEA19902.1  [L=465]
Description: cell wall glycosyl hydrolase Dfg5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   3.6e-162  540.0  19.6   4.3e-162  539.8  19.6    1.0  1  Glyco_hydro_76  Glycosyl hydrolase family 76
  ------ inclusion threshold ------
      0.022   13.9  11.7       0.29   10.2   0.2    2.9  3  Glyco_hydro_88  Glycosyl Hydrolase Family 88


Domain annotation for each model (and alignments):
>> Glyco_hydro_76  Glycosyl hydrolase family 76
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  539.8  19.6  4.8e-166  4.3e-162       1     365 [.      34     400 ..      34     401 .. 0.99

  Alignments for each domain:
  == domain 1  score: 539.8 bits;  conditional E-value: 4.8e-166
                     SXHHHHHHHHHHHHHHCETTECCTCTCBSCES-GHHHHHHHHHHHHHHHHHCTTCCCHHHHHHHHHCCCTCEE-SSSTTCTCSSEHHHHHHHHHH CS
  Glyco_hydro_76   1 siksaaatiakgllkyYkgnesggtpgnlpdpyywWeagalfgalidywrltgdstyndlitqallaqagenydympanqsrtegnDDqafwgla 95 
                     siksaa+++a+++++yY+g+++g++pgnlpdpyywWeaga+fgal+dyw +tgdst+n+++tqall+qa+++ ++mp+nq++tegnDDqafwg+a
      EEA19902.1  34 SIKSAAKAVATEMMTYYTGYRPGDNPGNLPDPYYWWEAGAMFGALVDYWAYTGDSTWNSITTQALLWQASPDANFMPKNQTMTEGNDDQAFWGMA 128
                     79********************************************************************************************* PP

                     HHHHHHH......H--HHHHHHHHHHHHHHHHCB-SCSCCS-BBSEC..ESS--SEEEHHHHHHHHHHHHHHHHHH--CHHHHHHHHHHHHHHHH CS
  Glyco_hydro_76  96 amtaaernfpep.tdepswLalAqavfntqasrwdeetcgGGlrWqiftwnsgydyknsisngplfqlaarLarytgnetYlewAekvwdWvedv 189
                     am+aaernfp+p +d+p+wLalAqavfn qa rwd ++cgGGlrWqiftwn+g  ykn+isng++f++a+rLa+ytgn+tY++wA+k w+W++dv
      EEA19902.1 129 AMSAAERNFPNPpPDQPQWLALAQAVFNSQALRWDLTSCGGGLRWQIFTWNNGFGYKNTISNGGFFNIASRLAKYTGNHTYADWADKSWQWIVDV 223
                     *********************************************************************************************** PP

                     SCSBTTTS-B-SEEETTTCCEEEE---HHHHHHHHHHHHHHHHHHH.--HHHHHHHHHHHHHHHHHCEEC.TTEEEEEE-TTSTTCCTTHHHHHH CS
  Glyco_hydro_76 190 gliddedwlvyDgasvednctdinklqwtYnqGtylsgaaylynaT.gdekWldrvkgllnatlstffpd.gnilyevacepsekcnnDqrsFkg 282
                     g++ + +++++Dga++ ++c++ n+++wtYn+G+yl gaa +yn+T g++ W+drv ++lnat+ +f +d +n++ye+ace+  +c+ DqrsFk+
      EEA19902.1 224 GFL-TPEYRFWDGADDATDCNSYNQIEWTYNSGVYLLGAANMYNYTnGSDIWRDRVLEILNATKVFFSTDpENVMYERACETVGTCQVDQRSFKA 317
                     ***.***********************************************************8888888************999********** PP

                     HHHHHHHHHH..SHHHHHHHHHHHHHHHHHHHTTTB...TTTSB-TTTTTSSCCHHHHHHHHCCHHH............HHHH CS
  Glyco_hydro_76 283 ilarwlaltaqlapetadtiepllrasaeaaakscsggsdgttcglkwlkgtwdgdaglgeqmsaleviqallveekkaplta 365
                     +++rw+a+t+q+ap+t+d i+p lrasa aaak+c+gg +gt cgl+w+ ++wdg+ glgeqmsalev+q++l++e+++p+t+
      EEA19902.1 318 YFSRWMAATTQMAPFTYDIIMPRLRASALAAAKTCTGGPNGTSCGLRWTDQEWDGSRGLGEQMSALEVVQSNLIHEVAPPVTD 400
                     *****************************************************************************999986 PP

>> Glyco_hydro_88  Glycosyl Hydrolase Family 88
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   1.1   4.2e-05      0.38       3      67 ..      40     107 ..      38     135 .. 0.72
   2 ?   -0.1   0.3     0.043   3.9e+02      31      61 ..     190     220 ..     171     225 .. 0.69
   3 ?   10.2   0.2   3.2e-05      0.29      21      50 ..     244     273 ..     230     312 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 4.2e-05
                     HHHHHHHHHHTTT--CCT...SSTTCCE.HHHHHHHHHHHHHHHHH--HHHHHHHHHHHHHCCCTTS- CS
  Glyco_hydro_88   3 kkvngsfikkkeegkvie...lkkenewewtnGvflsglleayeatgdkeyldyakawadslideggk 67 
                     k v+ ++++ ++ ++  +   + ++  + w+ G+++++l++++ +tgd++  +++++   ++   +++
      EEA19902.1  40 KAVATEMMTYYTGYRPGDnpgNLPDPYYWWEAGAMFGALVDYWAYTGDSTWNSITTQALLWQASPDAN 107
                     55667777777777777755534555566*********************999999876666655555 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.043
                     HHHHHHHHHHHHHHH--HHHHHHHHHHHHHC CS
  Glyco_hydro_88  31 nGvflsglleayeatgdkeyldyakawadsl 61 
                     nG f++   +++++tg+ +y d+a++  ++ 
      EEA19902.1 190 NGGFFNIASRLAKYTGNHTYADWADKSWQWI 220
                     4445555558899999999999998866655 PP

  == domain 3  score: 10.2 bits;  conditional E-value: 3.2e-05
                     SSTTCCE.HHHHHHHHHHHHHHHHH--HHH CS
  Glyco_hydro_88  21 lkkenewewtnGvflsglleayeatgdkey 50 
                       ++ ew ++ Gv+l g +++y++t+ +++
      EEA19902.1 244 SYNQIEWTYNSGVYLLGAANMYNYTNGSDI 273
                     456789********************9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (465 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       391  (0.0218082); expected 358.6 (0.02)
Passed bias filter:                      280  (0.0156172); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.71u 0.33s 00:00:01.04 Elapsed: 00:00:00.58
# Mc/sec: 2408.21
//
Query:       EEA19903.1  [L=239]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        1.7    8.5   2.7        2.3    8.0   2.7    1.2  1  RIFIN     Rifin


Domain annotation for each model (and alignments):
>> RIFIN  Rifin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   2.7   0.00013       2.3     114     249 ..      63     205 ..      60     237 .. 0.43

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00013
       RIFIN 114 gLgggvapsvGllggiavaawkkaa..laaaieaaie.....ageaagikaviellkkllklselkekkleslitatnyknvtslvkaikeeyeescll 205
                 +Lgg +   ++ +gg ++ +w + +  +a+ ++aa++     ag+a  ++   +   + +  +  +e++  s   a+++++ +s++   ++   +s ++
  EEA19903.1  63 NLGGQLGSDLSSIGGSITSGWGSFThsIATYTSAAASdysrwAGDASSLASDASVQATSWAARAATETNSASASIASQFASDASIIADNESSAASSLAS 161
                 677777778888888888887544422444444444444444222222222211111112222222222223323455555555555444443333333 PP

       RIFIN 206 klkkskaaltsakekekkeasskekikkkvekivekaekkaaaa 249
                  ++++ a++t +++ + +++ ++++ + +++++ +++   a+aa
  EEA19903.1 162 RASNTVAHVTGMSTVTGATTLTNSAGSATATSTFTSTHAGATAA 205
                 33333333222222222222222222222222222222221111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (239 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1027  (0.0572815); expected 358.6 (0.02)
Passed bias filter:                      278  (0.0155056); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.66u 0.36s 00:00:01.02 Elapsed: 00:00:00.55
# Mc/sec: 1300.94
//
Query:       EEA19904.1  [L=374]
Description: aquaporin [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.5e-46  157.7  14.8      5e-46  157.2  14.8    1.1  1  MIP            Major intrinsic protein
  ------ inclusion threshold ------
       0.32   11.8   8.5       0.24   12.2   6.1    2.0  2  Orthopox_C10L  Orthopoxvirus C10L protein


Domain annotation for each model (and alignments):
>> MIP  Major intrinsic protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  157.2  14.8   5.5e-50     5e-46       8     227 .]      45     260 ..      39     260 .. 0.91

  Alignments for each domain:
  == domain 1  score: 157.2 bits;  conditional E-value: 5.5e-50
                 HHHHHHHHHHHHHHHHHHHH.HHHCCCSSCSSSSTTSS.HHHHHHHHHHHHHHHHHHHHHHHCHT-S-SHHHHHHHHHTTSSSHHHHHHHHHHHHHHHH CS
         MIP   8 lravlAEflatlllvfigvg.salnvkkkvsslaslvs.vtleavalafglalavlvylaagiSGaHlNPavTlallvarkisllrailYivaQllGai 104
                 + a++ Ef++t++++f+g   ++++   + +  +s ++  +l+ ++l+fg++l+v v ++  + G+ +NPavTlal++++ ++++r+++ +++Q++ +i
  EEA19904.1  45 MIAAIGEFVGTFMFLFFGFVgAQVANTPAPEP-GSGPDtSKLLYISLVFGFSLTVNVWAFYRVTGGMFNPAVTLALFLVGGLPAIRGVFVVISQIVAGI 142
                 567899************87588866655554.55555589********************************************************** PP

                 HHHHHHHHHCHHHHHHTTTTSSSSSTTSSHHHHHHHHHHHHHHHHHHHHHHCSTTSSSSTCHGHHHHHHHHHHHHHHHHHHHHST-SSHHHHHHHHHHH CS
         MIP 105 vaaallklltkglesraglfanslkpglsagqalvvEiiltfvLvlvvfaltddkrkvslgelaplaigllvaliilvgipltGaamNpArslgpavvl 203
                 +aaa++++l+ g         n+l  g++++q+l++E++lt +Lv+v++ l+  k+k +   lap+ igl+++l++l gi++tGa++N Arslgpavv 
  EEA19904.1 143 CAAAVVSALFPGP----LNVENTLGGGTNVAQGLFIEMFLTSQLVFVIIMLAVVKHKST--FLAPVGIGLTLFLCHLTGIYFTGASLNFARSLGPAVVN 235
                 ************6....555667889**********************99998887776..89************************************ PP

                 THS.TTTTHHHHHHHHHHHHHHHHH CS
         MIP 204 nkf.edhwvylvGPliGailgalvY 227
                 ++f +++w+y++GP++G+ l++  Y
  EEA19904.1 236 HSFpHYFWIYFLGPMLGSCLASSFY 260
                 **85789*************99776 PP

>> Orthopox_C10L  Orthopoxvirus C10L protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   6.1   2.7e-05      0.24      47      79 ..     289     321 ..     283     325 .. 0.84
   2 ?   -1.7   0.0      0.59   5.3e+03      14      37 ..     330     353 ..     321     365 .. 0.56

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2.7e-05
  Orthopox_C10L  47 kkhvgggsggifGgssgvkgGvkGGvnGGvngG 79 
                    ++     +gg  G s+gv+ Gv  GvnG vng 
     EEA19904.1 289 RQLSSSTTGGDLGVSNGVSNGVSNGVNGDVNGS 321
                    566677889999******************985 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.59
  Orthopox_C10L  14 GtykgfandpgGavkrpkslssGg 37 
                     + + +a  + G + + k  +sGg
     EEA19904.1 330 TNISETAAINSGYADKNKNEASGG 353
                    455555555555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (374 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       664  (0.037035); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.31s 00:00:00.90 Elapsed: 00:00:00.51
# Mc/sec: 2198.61
//
Query:       EEA19905.1  [L=568]
Description: MFS sugar transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   5.6e-116  388.1  29.7   1.2e-115  386.9  29.7    1.5  1  Sugar_tr  Sugar (and other) transporter
    1.2e-19   70.5  45.2    4.4e-15   55.5  21.3    2.1  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
        1.9    8.5   8.2        1.9    8.6   3.6    2.8  2  DUF5391   Family of unknown function (DUF5391)


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  386.9  29.7  2.1e-119  1.2e-115       2     452 .]      39     521 ..      38     521 .. 0.93

  Alignments for each domain:
  == domain 1  score: 386.9 bits;  conditional E-value: 2.1e-119
                 HHHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTS CS
    Sugar_tr   2 alvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgkn 100
                 a++a+lggll+gY+ gv +++lt+++f ++ g+++++s+k+      g+++si+ +Ga +G l++g+l+++++Rk+++li +++f+ g ++q +a + +
  EEA19905.1  39 AMFACLGGLLYGYNQGVFSGVLTMTAFGNHMGAYTTDSTKK------GWLTSILELGAWFGTLYSGFLAEVLSRKYAILINTAIFILGVIIQCTAVSSS 131
                 6899*********************************9887......8*************************************************** PP

                 S-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-......TTHHHHHHHCCHHHHHHHHHHGGGS-- CS
    Sugar_tr 101 svevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsn......adgwrillglqlvpallllilllflPE 193
                     +++gR+++G+gvG  s++vPmy +E Ap+++Rg lvsl+q++i fGil+++++++g+n++++      +  w i+l lqlvpa++l+++++f+P 
  EEA19905.1 132 GANSILAGRFITGMGVGSLSMIVPMYNAECAPPEIRGLLVSLQQFSIEFGILISFWIDYGTNYIGGtgdsqsDAAWLIPLCLQLVPAVILFAGMIFMPF 230
                 ***********************************************************************999************************* PP

                 -HHHHHHTT-HHHHHHHHHHHHHC........HHHHHHHHHHHHHHHHHHH............................HTTHHHHSH...HHHHHHHH CS
    Sugar_tr 194 SPrylvekgkeeeakevlaklrge........edadrelaeekdsleaeqeee.......................kaswkellssktvrqrlligvvl 261
                 SPr+lv++++e+ea +v+a l g         e  + e+ e+k++       e                        + +++l++++ +++r++++ v+
  EEA19905.1 231 SPRWLVHHDREDEAHRVIAMLHGGsgtsaaidEVIELEFLEIKAQSMF----EkrstaekfphlqeqtpwntfklqFVAIGSLFKTMPMFRRVIVATVT 325
                 ********************8888344444433333344444444333....14555889******8888777777777778888877*********** PP

                 HHHHHHTTHHHHHHHTTTHHHHSS-THH...HHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS.......CHHHH CS
    Sugar_tr 262 qifqqltGinaimyysptifenlglsks...llvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgivalllvaks....kaasivai 353
                 ++fqq tGina++yy+p+if  lgls+    ll+t++vg+v f++t+  +  vdr+GR+++l+ Ga+ m i  +i++ + +++++ +    kaa+ +ai
  EEA19905.1 326 MFFQQWTGINAVLYYAPSIFGALGLSNNttsLLATGVVGIVMFLTTIPMMVYVDRIGRKPVLIAGAIAMGINHLIIA-IIFAIEQDQwpthKAAGWAAI 423
                 ***************************9999*********************************************9.8888888888999******** PP

                 HHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 354 vfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 v++ lf+  f+++wgp+ w++v+E+ p+s R+ ++a+ + +nw+ nf++++++p +  ++  +++f++f+++ ++++ fv++fvpetk +tlee++ +f
  EEA19905.1 424 VMVWLFAGNFGWSWGPCAWIIVAEVWPLSARPYGIALGASSNWMNNFIVGQVTPDMITHMR-YGTFIFFGVMTLVGAAFVWMFVPETKQLTLEEMDVIF 521
                 *************************************************************.*********************************9987 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.5  21.3   7.3e-19   4.4e-15       2     257 ..      43     367 ..      42     369 .. 0.80
   2 !   26.9  25.6   3.6e-10   2.1e-06       5     175 ..     327     509 ..     319     519 .. 0.78

  Alignments for each domain:
  == domain 1  score: 55.5 bits;  conditional E-value: 7.3e-19
       MFS_1   2 llaaflsalarsilgpalpl.alaedlg...ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll..fa..sslwlllvlr 92 
                 +l+++l++++ ++++ +l++ a +++ g    + +  g+l+++  lga++++l  G+l++ ++r+  +l+  ++f+lg +++    +  s+   +l++r
  EEA19905.1  43 CLGGLLYGYNQGVFSGVLTMtAFGNHMGaytTDSTKKGWLTSILELGAWFGTLYSGFLAEVLSRKYAILINTAIFILG-VIIQctAVssSGANSILAGR 140
                 688899999999999999876776664444488899**************************9999************.555533324544447***** PP

       MFS_1  93 vlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg.........Wravfyilaivsllafvlfllllpeepperkrk 182
                 +++G+g g+l  ++  + a+ +p+e rg+ ++l + ++ +G+++   +       +g         W  +  +  + ++++f  +++++p +p+     
  EEA19905.1 141 FITGMGVGSLSMIVPMYNAECAPPEIRGLLVSLQQFSIEFGILISFWIDYGTNYIGGtgdsqsdaaWLIPLCLQLVPAVILFA-GMIFMPFSPRWLVHH 238
                 **************************************************9997777*****999999999999999999877.335554444444444 PP

       MFS_1 183 spkeee............................................kgtgpaplvp......awkallkdpvlw.....illialllfffgfsgl 226
                   ++e                                             + ++++p+ +      a+++l+k  +++     + +++++  ++g++++
  EEA19905.1 239 DREDEAhrviamlhggsgtsaaidevielefleikaqsmfekrstaekfpHLQEQTPWNTfklqfvAIGSLFKTMPMFrrvivATVTMFFQQWTGINAV 337
                 44444488899999999999999999999999999999999999999999555555555555677756666666666556566788888888999999* PP

       MFS_1 227 ltllplylqevlgls.glllaglllallalvg 257
                 l++ p++    lgls +  +++l+ +++++v+
  EEA19905.1 338 LYYAPSI-FGALGLSnN-TTSLLATGVVGIVM 367
                 ******7.*******63.44454566666665 PP

  == domain 2  score: 26.9 bits;  conditional E-value: 3.6e-10
       MFS_1   5 aflsalarsilgpalplalaedlgispseigllltl.yalgaavaslplGrlsdrfGrrrvlllglllfalg.lllll.fa...........sslwlll 89 
                 +f   +++++++  +p  +  +lg+s  + +ll+t+ ++++++++++p+++ +dr+Gr++vl++g++++++  l++++ fa           +++ +++
  EEA19905.1 327 FFQQWTGINAVLYYAP-SIFGALGLSNNTTSLLATGvVGIVMFLTTIPMMVYVDRIGRKPVLIAGAIAMGINhLIIAIiFAieqdqwpthkaAGWAAIV 424
                 3333444444555556.999************88887999********************************666666875555555556656666788 PP

       MFS_1  90 vlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGa.ilgpllggllasslgWravfyilaivsllafvlfllllpee 175
                  +++++G ++ +  p + +++a+++p + r+ +i+l ++++ +   i+g +   +++ +    ++f+++++++l+++ ++++++pe+
  EEA19905.1 425 MVWLFAGNFGWSWGPCAWIIVAEVWPLSARPYGIALGASSNWMNNfIVGQVTPDMIT-HMR-YGTFIFFGVMTLVGAAFVWMFVPET 509
                 888888888777889999**************************9666666666777.544.478***********99855555544 PP

>> DUF5391  Family of unknown function (DUF5391)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.1     0.071   4.3e+02     101     119 ..     110     128 ..      83     138 .. 0.69
   2 ?    8.6   3.6   0.00031       1.9      41      98 ..     352     407 ..     319     435 .. 0.79

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.071
     DUF5391 101 lsdseassllgvivlcias 119
                 +  ++a ++lgvi+ c a+
  EEA19905.1 110 ILINTAIFILGVIIQCTAV 128
                 3345678899999999886 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.00031
     DUF5391  41 nqfnslgmwksiGiillfylvplllyilgikalrfvmailcgvGllidlvllavvfls 98 
                 n+  sl     +Gi++++  +p+++y+  i    +++a  +++G+     ++a +f +
  EEA19905.1 352 NNTTSLLATGVVGIVMFLTTIPMMVYVDRIGRKPVLIAGAIAMGIN--HLIIAIIFAI 407
                 555666667789*****************99999999999999984..4445555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (568 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       693  (0.0386525); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 3769.08
//
Query:       EEA19906.1  [L=308]
Description: beta-alanine synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.4e-21   74.6   0.0      1e-20   74.4   0.0    1.1  1  Peptidase_M20  Peptidase family M20/M25/M40
    3.1e-05   23.8   0.0    5.4e-05   23.1   0.0    1.4  1  M20_dimer      Peptidase dimerisation domain


Domain annotation for each model (and alignments):
>> Peptidase_M20  Peptidase family M20/M25/M40
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.4   0.0   1.1e-24     1e-20      88     205 ..      67     294 ..      29     296 .. 0.91

  Alignments for each domain:
  == domain 1  score: 74.4 bits;  conditional E-value: 1.1e-24
                    TTCESEEEEEEEESSSBTCHSTETEEEE.................................................................... CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxx.................................................................... RF
  Peptidase_M20  88 rekvdavfelhieepgileagklaigvv.................................................................... 115
                    ++++ a felhie+++ile  + +igvv                                                                    
     EEA19906.1  67 GYPLSAHFELHIEQGPILEHTNRSIGVVqgsqayrwlsftisgrdahtgttplsarrdpllaasrmiassneiaqrygalastgifkipsnastnt 162
                    6789999***************************************************************************************** PP

                    .......................................EEEEEEE..EEESHEEECCHHHHHHHHHHHHHHH.TSCEEEEEESSSBHTHHHH.TT CS
                    .......................................xxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxx.xx RF
  Peptidase_M20 116 .......................................kvevell..eggapvtlndsplvkalaeaaeelf.gekvelivsgpggtdarff.ag 168
                                                            v++ +    ++a+v+++ + +++a+++aa +l+   k+++i+sg +g+d  +   +
     EEA19906.1 163 iasevtftldirhpddtvvdtvqaeclesfnkiaaqdgkGVSFAWQidTDSAAVRFD-ENCINAVRAAAHNLVgPGKYMDITSG-AGHDGVYTsRR 256
                    **************************************7477777733666666666.***************52469999***.********555 PP

                    TEEEEEEESS.GGCTTSTTTEEEHHHHHHHHHHHHHHH CS
                    xxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_M20 169 iptvmifgpg.sglaHspnEyvdledlekgikvlarll 205
                     pt mif+p+ +g +H+p+Ey++led++ g+++l +++
     EEA19906.1 257 CPTTMIFVPCrDGVSHNPEEYCSLEDCAIGTQALLEAV 294
                    5*********66**********************9987 PP

>> M20_dimer  Peptidase dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.1   0.0     6e-09   5.4e-05       6     108 ..     100     199 ..      95     200 .. 0.88

  Alignments for each domain:
  == domain 1  score: 23.1 bits;  conditional E-value: 6e-09
                 EEEEEEEEE-B-EEGG.-TTTTB-.HHHHHHHHHHCSCTTEEC.....TCCTCCCCCEECCE-C...CCCEESSEEEEEEEEEHHHHHHHHHHHHHHHH CS
   M20_dimer   6 laggkitvkgkagHsg.apgagaN.AieklarllaeledeegdiaeerslprttlnvtgiegGs...aknvipdeaeakidiRllpgedpeevleeiee 99 
                 + +   t+ g+++H g  p  ++  ++ +++r++a+ ++  ++        + +l+ tgi       ++n+i++e+++++diR ++   +++v++e  e
  EEA19906.1 100 YRWLSFTISGRDAHTGtTPLSARRdPLLAASRMIASSNEIAQR--------YGALASTGIFKIPsnaSTNTIASEVTFTLDIRHPDDTVVDTVQAECLE 190
                 5688899*********999887656***************877........5599999999988899****************************9999 PP

                 HHTSCCSTT CS
   M20_dimer 100 ilekeaped 108
                  ++k a++d
  EEA19906.1 191 SFNKIAAQD 199
                 999988775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (308 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       321  (0.017904); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2146.30
//
Query:       EEA19907.1  [L=344]
Description: D-mandelate dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.8e-41  140.8   0.0    4.6e-41  140.1   0.0    1.4  1  2-Hacid_dh_C    D-isomer specific 2-hydroxyacid dehydrogenase
    1.5e-10   40.8   0.0      2e-10   40.4   0.0    1.2  1  2-Hacid_dh      D-isomer specific 2-hydroxyacid dehydrogenase
    8.9e-08   32.5   0.0    1.6e-07   31.6   0.0    1.4  1  NAD_binding_2   NAD binding domain of 6-phosphogluconate dehy
    8.9e-06   26.2   0.0    1.9e-05   25.1   0.0    1.6  1  F420_oxidored   NADP oxidoreductase coenzyme F420-dependent
    0.00084   19.7   0.0      0.014   15.8   0.0    2.4  2  UDPG_MGDP_dh_C  UDP-glucose/GDP-mannose dehydrogenase family,
     0.0089   15.1   0.0      0.015   14.3   0.0    1.3  1  PDH             Prephenate dehydrogenase
  ------ inclusion threshold ------
       0.25   11.5   0.9        2.4    8.4   0.0    2.7  3  DUF4242         Protein of unknown function (DUF4242)


Domain annotation for each model (and alignments):
>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.1   0.0   1.8e-44   4.6e-41       3     178 .]     126     306 ..     124     306 .. 0.90

  Alignments for each domain:
  == domain 1  score: 140.1 bits;  conditional E-value: 1.8e-44
                   HHHHHHTTHHHHHHHHHTT...CC...HTTCCGSBS-GTTSEEEEES-SHHHHHHHHHHH.HTT-EEEEESSSHHHHHCHHHHTCEEC.SHHHHHHH CS
  2-Hacid_dh_C   3 lllallrrlaeadeevreg...ew...ksekallgkelsgktvGiiGlGrIGqavakrlk.afgmkviaydrskkkeeeeeelgvelv.sleellae 91 
                   ++l++ r+l++   + ++g   +w   +++++l+  + +gkt+G+iGlG+IG ++a+++  afgmk++++d+++k+ e+e++ +++++ s eel+++
    EEA19907.1 126 HILNVFRNLKWSLVAAHSGsaeQWqeaHKNTQLTAWNPRGKTLGMIGLGNIGYTIAEKAYrAFGMKILYHDPYRKSAEQERAIEATYCaSNEELVSQ 222
                   688888998888777766644477776667788889********************99977**************99988888885555******** PP

                   -SEEEE-S--STTTTTSBSHHHHHCSTTTEEEEESS-GGGB-HHHHHHHHHTTSCCEEEES--SSSSSGTCHHHHHSTTEEE-SS-T CS
  2-Hacid_dh_C  92 sDivslhlpltpetrhlinaeelakmkkgailiNtaRGglvdeeaLleaLksgkiagaalDvfeeeplpedspllelpnviltPHia 178
                    D+v+l++p     +++i+ae l+++++g+ +iN+aRG+lvdeea+++aL+sgk+++++lDv ++ep  +  +++++ nv lt H+a
    EEA19907.1 223 VDCVVLAMPFG--GKEIIDAELLSHFRDGSRFINIARGKLVDEEAVIAALESGKLHAVGLDVQYNEPHVHP-KMATMRNVALTCHTA 306
                   *********86..579*****************************************************77.99***********97 PP

>> 2-Hacid_dh  D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.4   0.0     8e-14     2e-10      51     134 .]      71     338 ..      33     338 .. 0.96

  Alignments for each domain:
  == domain 1  score: 40.4 bits;  conditional E-value: 8e-14
                 BSHHHHHHH.TT--EEEESSSSCTTB-HHHHHHTT-EEEE-TTTTHHHHHHHH.............................................. CS
                 xxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.............................................. RF
  2-Hacid_dh  51 vtaevleal.pkLkviaragvGvDnvDldaakerGilVtnvpgystesvAElt.............................................. 102
                  ++e+   l +++kv a ag+G+D  D+d ++ +Gil +n  ++s+e+vA+++                                              
  EEA19907.1  71 WDKELVPLLpESVKVFASAGAGYDWADVDVLADHGILYCNGAAASSEAVADTAiyhilnvfrnlkwslvaahsgsaeqwqeahkntqltawnprgktlg 169
                 577888888899*************************************************************************************** PP

                 ................................................................................................... CS
                 ................................................................................................... RF
  2-Hacid_dh 103 ................................................................................................... 102
                                                                                                                    
  EEA19907.1 170 miglgnigytiaekayrafgmkilyhdpyrksaeqeraieatycasneelvsqvdcvvlampfggkeiidaellshfrdgsrfiniargklvdeeavia 268
                 *************************************************************************************************** PP

                 ......................................T-BHHHHHHHHHHHHHHHHHHHTTCCGTTBCS CS
                 ......................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  2-Hacid_dh 103 ......................................aaTeeaqeniaeeaaenlvaflkgespanavn 134
                                                       +   +++    + a+en+++++ g++p +avn
  EEA19907.1 269 alesgklhavgldvqynephvhpkmatmrnvaltchtaGGAMDTVLGFERLAMENCERVILGQEPLTAVN 338
                 ************************************99999999*********************99998 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.6   0.0   6.2e-11   1.6e-07       2     114 ..     168     280 ..     167     286 .. 0.92

  Alignments for each domain:
  == domain 1  score: 31.6 bits;  conditional E-value: 6.2e-11
                    EEEE--SHHHHHHHHHHHHT.T-EEEEE-SSHHHHHHHHHTTEEE-SSHHHHHHHCSEEEE-SSSHHHHHHHHHS.HCCC--TT-EEEE-S---HH CS
  NAD_binding_2   2 igfiGlGvMGsnmalnllka.gykvavynrtkekveelvaegakaaesieelvasldvvitmvkagkavdevieg.llealkkgdilidgstsspe 95 
                    +g+iGlG++G  +a++  +a g+k+  ++  ++++e+  a +a+ ++s eelv+++d+v++ ++ g   +e+i+  ll++++ g+ +i+ +  +  
     EEA19907.1 168 LGMIGLGNIGYTIAEKAYRAfGMKILYHDPYRKSAEQERAIEATYCASNEELVSQVDCVVLAMPFGG--KEIIDAeLLSHFRDGSRFINIARGKLV 261
                    8***************97554********999999999999***********************986..6888888******************** PP

                    HHHHHHHHHHHTT-EEEEE CS
  NAD_binding_2  96 dtrelakelkekglkflda 114
                    d + + ++l++ +l+ ++ 
     EEA19907.1 262 DEEAVIAALESGKLHAVGL 280
                    *************999986 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1   0.0   7.5e-09   1.9e-05       2      92 ..     168     253 ..     167     258 .. 0.81

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 7.5e-09
                    EEEETTSHHHHHHHHHHHHT.TS-GGCEEEEEESSCCCHHHHHHHHC-EEECECHHHHHHH-SEEEE-S-HHHHHHHHHHCGHHHHTTSEEE CS
  F420_oxidored   2 igiiGaGnmgealasgllaa.gaqpheivvansrnpekaeelaeelgvkvtavdneeaaeeadvvvlavkpedveevlselakdalkgklvi 92 
                    +g iG Gn+g ++a+++ +a g    +i+   +    k +e +++++++ +a +nee++++ d vvla+++   e + +el ++   g+ +i
     EEA19907.1 168 LGMIGLGNIGYTIAEKAYRAfG---MKIL--YHDPYRKSAEQERAIEATYCA-SNEELVSQVDCVVLAMPFGGKEIIDAELLSHFRDGSRFI 253
                    799*************999934...6676..4777777889999********.*****************9877777666666665555555 PP

>> UDPG_MGDP_dh_C  UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   5.4e-06     0.014      28      74 ..     187     230 ..     179     242 .. 0.90
   2 ?    0.9   0.0      0.23   5.9e+02      25      54 ..     274     299 ..     266     328 .. 0.80

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 5.4e-06
                     HCTSEEEEE-SSTHHCCCCHHGGBTCCEEES-CHHHHTT-SEEEE-S CS
  UDPG_MGDP_dh_C  28 eegaevkiyDPkvkeeaveaeleekgvevvdsleealkgadaivilt 74 
                     + g+++ ++DP+ k++++e+   + ++++++s ee ++++d++v++ 
      EEA19907.1 187 AFGMKILYHDPYRKSAEQER---AIEATYCASNEELVSQVDCVVLAM 230
                     56999*************99...5679*****************986 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.23
                     HHHHCTSEEEEE-SSTHHCCCCHHGGBTCC CS
  UDPG_MGDP_dh_C  25 eLleegaevkiyDPkvkeeaveaeleekgv 54 
                     +L++ g +v++ +P+v ++ + +    ++v
      EEA19907.1 274 KLHAVGLDVQYNEPHVHPKMATM----RNV 299
                     57778999*********998887....333 PP

>> PDH  Prephenate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   5.9e-06     0.015      10      73 ..     188     250 ..     181     268 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 5.9e-06
                 --SEEEEE-SSHHHHHHHHHTTSSSEEES-GGGGCCGSEEEE-S-GGGHHHHHHHHHHHS-TT- CS
         PDH  10 fkvtvigydideekaeaalelglvdeatddieavkeadivvlavPvevilevlkelaphlkeda 73 
                 f  ++   d   ++ae+ +++++ ++a ++ e v++ d vvla+P    + + +el +h + + 
  EEA19907.1 188 FGMKILYHDPYRKSAEQERAIEATYCASNE-ELVSQVDCVVLAMPFGGKEIIDAELLSHFRDGS 250
                 557888999999*****************6.***************999999999998887765 PP

>> DUF4242  Protein of unknown function (DUF4242)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   0.0   0.00093       2.4      25      62 ..      84     122 ..      79     124 .. 0.85
   2 ?   -1.4   0.0         1   2.7e+03      11      23 ..     144     156 ..     134     160 .. 0.77
   3 ?   -0.9   0.0      0.74   1.9e+03      12      34 ..     201     224 ..     194     228 .. 0.70

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00093
                 HHHGG..GT-EEEEEEEETTTTEEEEEEE-S-HHHHHHH CS
     DUF4242  25 avlael.egvqwlrsyvtedkgkvfClyeApdeeavreh 62 
                 +v a    g  w    v +d+g  +C   A + eav  +
  EEA19907.1  84 KVFASAgAGYDWADVDVLADHGILYCNGAAASSEAVADT 122
                 55566667899*************************876 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 1
                 --HHHHHHHHHHH CS
     DUF4242  11 itaeelaaaaaks 23 
                  +ae++++a+++ 
  EEA19907.1 144 GSAEQWQEAHKNT 156
                 4789999999875 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 0.74
                 -HHHHHHHHHHHHHHHGG..GT-E CS
     DUF4242  12 taeelaaaaakslavlael.egvq 34 
                 +ae+ +a+ a+++a  +el  +v 
  EEA19907.1 201 SAEQERAIEATYCASNEELvSQVD 224
                 677777888888887777666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (344 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       375  (0.0209158); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2387.31
//
Query:       EEA19908.1  [L=455]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.081   13.3   3.5        3.6    8.1   0.3    2.5  2  REV1_C           DNA repair protein REV1 C-terminal domain
        2.1    8.1   6.1       0.58    9.9   0.2    2.6  3  Sulfotransfer_4  Sulfotransferase domain


Domain annotation for each model (and alignments):
>> REV1_C  DNA repair protein REV1 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.2    0.0024        21      43      82 ..     147     186 ..     122     188 .. 0.85
   2 ?    8.1   0.3    0.0004       3.6      16      81 ..     206     269 ..     199     278 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0024
      REV1_C  43 avavlkwlrvlleeeeeskeeeageaWekafrevkeavqe 82 
                 ++++  w+++ +  + +++   ++ +W++a+ ++ke+v++
  EEA19908.1 147 IEQIFIWMKQTVSPSYHKTCIAVTANWKEAYINLKEQVNQ 186
                 45677799999998888999999***************96 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0004
      REV1_C  16 egPneeDvealakyLkkvv..eeerdlekavavlkwlrvlleeeeeskeeeageaWekafre.vkeavq 81 
                  +P  +D+ea  +  ++++  +e + +  a +vl w  + l+       +  ++aW +a++  ++e+++
  EEA19908.1 206 LKPSTRDLEAWITKWEELLleAERKSMVIADDVLDWSTRFLDAI-----RPLDDAWTTAYEItIEEKIE 269
                 57999*****99999999988888********************.....9**********853666665 PP

>> Sulfotransfer_4  Sulfotransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.3     0.066   5.9e+02     125     172 ..     140     185 ..     121     207 .. 0.54
   2 ?    9.9   0.2   6.5e-05      0.58      97     175 ..     210     293 ..     208     299 .. 0.77
   3 ?   -1.9   0.0      0.26   2.4e+03     143     174 ..     378     411 ..     350     446 .. 0.65

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.066
  Sulfotransfer_4 125 lldpllellaklvellralvrrlfgagsdaedeeaakeayeehnervr 172
                      + ++ +++ ++++ +++++v+  ++++    +++++keay + +e+v 
       EEA19908.1 140 WSEQ-KKAIEQIFIWMKQTVSPSYHKT-CIAVTANWKEAYINLKEQVN 185
                      4433.4444555555555555555553.33555555555555555554 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 6.5e-05
  Sulfotransfer_4  97 eRdpekWlksmkktllalrsetls...rllalldpllellaklvellralvrrlfgag.s.daedeeaakeayeehnervrevv 175
                      +Rd e+W ++++++ll++ ++ +     +l + +++l++ ++l +++ ++++  ++++    + +++++++a+++  +++r+  
       EEA19908.1 210 TRDLEAWITKWEELLLEAERKSMViadDVLDWSTRFLDAIRPLDDAWTTAYEITIEEKiEdGTLTRRELANAFRRNLRKIRNRR 293
                      8**************999988554344788888889999999999999999999888754234566777777777777777655 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 0.26
  Sulfotransfer_4 143 lvrrlfgag.s.daedeeaakeayeehnervrev 174
                      l+++l  ++   ++  + +ak++ e+h + v+++
       EEA19908.1 378 LFKNLAPEEfIpRWGPRMRAKKFAEDHPDLVKKI 411
                      4443333332234566667777777777777664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (455 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1145  (0.063863); expected 358.6 (0.02)
Passed bias filter:                      461  (0.0257125); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.42
# Mc/sec: 3229.97
//
Query:       EEA19909.1  [L=307]
Description: NmrA-like family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.1e-06   26.2   0.0    0.00019   21.1   0.0    2.8  2  NmrA            NmrA-like family
  ------ inclusion threshold ------
      0.025   14.5   0.0      0.076   12.9   0.0    1.7  2  NAD_binding_10  NAD(P)H-binding


Domain annotation for each model (and alignments):
>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.04   3.6e+02       1      18 [.       5      22 ..       5      37 .. 0.89
   2 !   21.1   0.0   2.1e-08   0.00019      83     224 ..      53     221 ..      40     235 .. 0.65

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.04
                EEESSTTSHHHHHHHHHH CS
        NmrA  1 IlviGaTGrqGksvvral 18
                I ++ a+G++G+s+v++l
  EEA19909.1  5 IDIFPAAGALGGSIVKHL 22
                56899**********987 PP

  == domain 2  score: 21.1 bits;  conditional E-value: 2.1e-08
                 HHHHHHHHHHS-SEEEEEE---GG.GT.SSS..---TTTHHHHHHHHHHHHC......................TS-EEEEEE-EEGGG-BSSS-SS-B CS
        NmrA  83 kklvdAakeaGvkhfiySslgddndrsnaee..pavphfdsKaeieeyvral......................gipytfvyagffmenflsllaqlkv 157
                  k +dAa + Gvkh++ySsl+ + + s+ ++    + h d+ a  +e    l                       i ++f++++    +++      + 
  EEA19909.1  53 RKAIDAALHSGVKHIFYSSLAFAGNLSKSSDalVMRAHLDTEAYLQE----LgrtrapdftftilreglyhesfPIYTSFFRPQEVIDVITDENTRRQS 147
                 5789***************9988877754440034555555555555....444448866666666666666555556666666666666666666666 PP

                 EEE-TTS.-EEEEESS-TTS-EE-HHHHHHHHHHHHHHH.HHH...H..TTEEEEE-S.EEE-HHHHHHHHHHH CS
        NmrA 158 gdtappedkvtllgpgnpkavlldaeeDiGafvikilkd.prk...l..kgkriklag.ntlsgneivelfekk 224
                 g  + +e +++++ +g++ +v   + +D G++ +ki+k   ++   +   ++ + l+g ++l++ne+v+++ek 
  EEA19909.1 148 GGGDHGEIQIKIPHDGSAPGVAWANRDDLGEASAKIVKLyMQNplgFpfTNSTLLLSGpKVLTLNEVVAVLEKL 221
                 66667777788888888888888999999999888887532221112222333333332567777777777775 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0     0.053   4.8e+02       2      38 ..      10      47 ..      10      54 .. 0.83
   2 ?   12.9   0.0   8.4e-06     0.076      77     145 ..      48     117 ..      28     145 .. 0.72

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.053
                    TTSHHHHHHHHHHHHC-.T-EEEEEETTHHHCHHHHCT CS
  NAD_binding_10  2 AtGkvGrllvkellarg.ghevtalvRnpeklaeleae 38
                    A G  G  +vk+l +     ++ +++R+p+ lae++++
      EEA19909.1 10 AAGALGGSIVKHLSSLIpASSLILVARRPDTLAEYSRQ 47
                    7899999999999998877889999******9998754 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 8.4e-06
                     H...HHHHHHHHHHCT--EEEEEEETTTTSGCGCHHHHHHHHCCHHHHHHHHHHHHH..HHHSSSEEEEEEE-C CS
  NAD_binding_10  77 g...aknivdaakeagvkRfvlvsaigvgdevpgefgewnkellkaylaakraaeel..lrasgldwTivrpgg 145
                     g   +++++daa  +gvk++ + s + +g+   ++ +     +++a l+  ++  el   ra ++++Ti+r g 
      EEA19909.1  48 GavaHRKAIDAALHSGVKHIFYSSLAFAGN-LSKSSDA---LVMRAHLDTEAYLQELgrTRAPDFTFTILREGL 117
                     145599****************99999995.2333322...34555555444444443356689******9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (307 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       368  (0.0205254); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.47
# Mc/sec: 1944.16
//
Query:       EEA19910.1  [L=1257]
Description: hypothetical protein PMAA_006770 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-38  132.7   0.2    2.9e-38  131.9   0.2    1.4  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    1.3e-05   24.9   0.0    3.5e-05   23.6   0.0    1.6  1  gag_pre-integrs  GAG-pre-integrase domain
  ------ inclusion threshold ------
      0.019   14.5   0.0      0.037   13.5   0.0    1.4  1  RVT_1            Reverse transcriptase (RNA-dependent DNA pol
      0.064   13.2   0.0       0.15   11.9   0.0    1.6  1  Flg_hook         Flagellar hook-length control protein FliK
      0.096   13.0   3.2       0.26   11.6   3.2    1.7  1  Orthopox_F14     Orthopoxvirus F14 protein


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  131.9   0.2   8.2e-42   2.9e-38       9     234 ..     761     983 ..     752     989 .. 0.91

  Alignments for each domain:
  == domain 1  score: 131.9 bits;  conditional E-value: 8.2e-42
       RVT_2   9 PkdrkaigsrWvftkkkddl.kevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeeelvvhqldvdsafLnaeldeevyvkqPpGfeid 106
                  k+++ +   W++  k+d++ + vk karlv++G  q    d  +++a  +   s r ++a+aa  +l + q d   af+na+ldee++++  pG+   
  EEA19910.1 761 AKGKQILDCMWIYVYKQDKKgRLVKCKARLVVRG-DQEKRDDMRDTYAATLAARSFRTFMAIAARFNLELKQYDAVNAFVNAKLDEEIFMRMAPGYR-- 856
                 577888999********999899***********.577889******************************************************96.. PP

       RVT_2 107 reeekvykLnkslyGlkqapllWnekidkvLkklgferseaesGlyvrgtgegklivalyvddlliagsdikil..edvkkelakkfklkdlgkvskfL 203
                  e++k+y+Lnk+lyGl+++pllW+++++++L klgf+  + e    +++     +++  yvdd+++a ++++ l  + + ++l +k++++   +++ fL
  EEA19910.1 857 -ESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFRAVPHEPCCMLKS----GVMLFFYVDDIVVAYKKSRQLeaNSILNQLRAKYNISGGEDLEWFL 950
                 .46****************************************999999....78999*********9999877225799******************* PP

       RVT_2 204 Gieiaq..eaggiklsladyiakvvkkfeltda 234
                 G+ i++  ++  i ls+a yi k++k ++ ++a
  EEA19910.1 951 GMRIIRdrSNKMIWLSQATYIDKIAKLADTQQA 983
                 ****986568889***********998876655 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.6   0.0   9.7e-09   3.5e-05      19      44 ..     163     188 ..     146     209 .. 0.77

  Alignments for each domain:
  == domain 1  score: 23.6 bits;  conditional E-value: 9.7e-09
  gag_pre-integrs  19 knkssinlWHrRLGHpsfsrlkkLfk 44 
                        k ++n+WH RLGHp+ + lk+L+ 
       EEA19910.1 163 ERKADANRWHARLGHPGPEVLKHLAG 188
                      35899*******************96 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0     1e-05     0.037     115     185 ..     848     932 ..     819     942 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 1e-05
                 ...........TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T................TEEECTTEEEEEESSHHH..HHHHHH CS
       RVT_1 115 svrv.nge.eskgryekkglpqGsvlSPllfnlfmnellrelrkra..........kgvtllrYaDDililskskee..lqelle 185
                  +r+  g  es+++y+ +    G+  SPll++  +++ l +l  ra          +gv l  Y+DDi++++k+  +  ++++l+
  EEA19910.1 848 FMRMaPGYrESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFRAvphepccmlkSGVMLFFYVDDIVVAYKKSRQleANSILN 932
                 444444455789999999999****************9999999999***************************88844444454 PP

>> Flg_hook  Flagellar hook-length control protein FliK
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   4.3e-05      0.15      34      69 ..    1143    1178 ..    1135    1194 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 4.3e-05
                  ETTEEEEEEEE-SCHHHHHHHHTHHHHHHHHHCCTT CS
    Flg_hook   34 rggqlsvqltaenpetrelLeqnlprLreaLaaaGl 69  
                  r +  ++++  +n++t+ lLe+++prLr+ L+   +
  EEA19910.1 1143 RFQTPTLHVYCDNQQTLGLLEKDAPRLRTKLRHVDI 1178
                  55566899**********************987544 PP

>> Orthopox_F14  Orthopoxvirus F14 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   3.2   7.3e-05      0.26      32      70 ..     440     477 ..     429     480 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 7.3e-05
  Orthopox_F14  32 idedditellniltelGcdvdfdedfsdiaddvleslie 70 
                   +  ++it ll  l +lG d dfd++++d+ d + + +++
    EEA19910.1 440 VSTQEITRLLTKL-DLGTDADFDDEYADLIDHITDVVFD 477
                   5667888888776.79***************99887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1257 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       468  (0.026103); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.78u 0.28s 00:00:01.06 Elapsed: 00:00:00.43
# Mc/sec: 8713.84
//
Query:       EEA19911.1  [L=258]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.4e-20   70.9   2.7    1.8e-10   40.6   0.6    2.3  2  Con-6     Conidiation protein 6
  ------ inclusion threshold ------
      0.079   12.7   0.6        2.2    8.1   0.0    2.3  2  RTP1_C2   Required for nuclear transport of RNA pol II C-term
        7.1    5.6   6.9         10    5.1   6.9    1.4  1  FAM199X   Protein family FAM199X


Domain annotation for each model (and alignments):
>> Con-6  Conidiation protein 6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.1   0.1     6e-11   3.6e-07      12      32 ..     152     172 ..     134     173 .. 0.93
   2 !   40.6   0.6   3.1e-14   1.8e-10       1      34 []     220     253 ..     220     253 .. 0.97

  Alignments for each domain:
  == domain 1  score: 30.1 bits;  conditional E-value: 6e-11
       Con-6  12 tLsNPnvSeeAKehAkeeLek 32 
                 tL+NPnvS  AKehA+++Le+
  EEA19911.1 152 TLNNPNVSASAKEHARHVLED 172
                 9******************97 PP

  == domain 2  score: 40.6 bits;  conditional E-value: 3.1e-14
       Con-6   1 dpenvirGyKAtLsNPnvSeeAKehAkeeLeklg 34 
                 +++nv rGyKA+ +N   ++++++hA+  Le++g
  EEA19911.1 220 NRTNVVRGYKAAAHNKANTDQGRQHARSALEDMG 253
                 689******************************8 PP

>> RTP1_C2  Required for nuclear transport of RNA pol II C-terminus 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.2     0.018   1.1e+02      22      31 ..     163     172 ..     161     172 .. 0.89
   2 ?    8.1   0.0   0.00037       2.2      22      31 ..     242     251 ..     241     252 .. 0.93

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.018
     RTP1_C2  22 ReHArdvLEe 31 
                 +eHAr vLE+
  EEA19911.1 163 KEHARHVLED 172
                 8*******96 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.00037
     RTP1_C2  22 ReHArdvLEe 31 
                 R+HAr++LE+
  EEA19911.1 242 RQHARSALED 251
                 9********8 PP

>> FAM199X  Protein family FAM199X
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   6.9    0.0017        10     198     244 ..      88     135 ..      34     168 .. 0.78

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0017
     FAM199X 198 eswkrssyssastsgvsaasssnasmvss.assstasvgssaansaan 244
                 +++  + +++++t+ vs+ass+ as   + + ++t+s +ss+++  a 
  EEA19911.1  88 DPFCNALFNATATAAVSSASSTGASSTGTrTGTATGSSASSTSSPGAA 135
                 667778889999999999999999876551344555555555443333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (258 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       879  (0.0490267); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.24s 00:00:00.70 Elapsed: 00:00:00.40
# Mc/sec: 1918.39
//
Query:       EEA19912.1  [L=369]
Description: transposable element tc1 transposase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.3e-12   45.3   0.2    2.1e-11   43.8   0.2    1.8  1  DDE_3          DDE superfamily endonuclease
    6.3e-10   39.2   0.5    1.7e-09   37.8   0.5    1.7  1  HTH_Tnp_Tc3_2  Transposase
     0.0015   18.3   1.6     0.0062   16.3   0.2    2.7  3  HTH_23         Homeodomain-like domain
     0.0077   16.2   0.0      0.022   14.7   0.0    1.8  1  HTH_12         Ribonuclease R winged-helix domain
     0.0092   15.7   0.1      0.023   14.5   0.1    1.6  1  HTH_38         Helix-turn-helix domain
     0.0093   16.4   0.1         13    6.3   0.0    3.4  4  DUF4350        Domain of unknown function (DUF4350)
  ------ inclusion threshold ------
      0.014   16.0  11.1       0.14   12.8   0.6    3.7  4  HTH_32         Homeodomain-like domain
      0.034   13.8   1.2          7    6.4   0.1    3.0  2  HTH_33         Winged helix-turn helix
      0.042   13.9   0.0        9.1    6.5   0.0    3.0  3  HTH_7          Helix-turn-helix domain of resolvase
       0.18   12.0   0.0       0.35   11.1   0.0    1.4  1  DUF2774        Protein of unknown function (DUF2774)
       0.21   11.3   0.5       0.54   10.0   0.0    2.0  2  Sigma70_r4_2   Sigma-70, region 4


Domain annotation for each model (and alignments):
>> DDE_3  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.8   0.2   1.3e-14   2.1e-11      77     145 ..     260     324 ..     244     325 .. 0.84

  Alignments for each domain:
  == domain 1  score: 43.8 bits;  conditional E-value: 1.3e-14
       DDE_3  77 qakkivlilDnasiHkseslrelveeeadrlellylPpySPelNpiEivwsklkrellkrrsfksldeL 145
                 q++ + l  D+ + H s++ ++ ++e   ++  +y+P+ SP+lNpiE vw+++k+++++  ++++ ++L
  EEA19912.1 260 QSIYLQLMQDGNPGHASKETKKELQE--RNIYPIYWPAFSPDLNPIEAVWNWMKDWIQE--QYPNDEQL 324
                 3335567779999*************..******************************9..66666665 PP

>> HTH_Tnp_Tc3_2  Transposase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.8   0.5     1e-12   1.7e-09       8      72 .]     102     163 ..      98     163 .. 0.92

  Alignments for each domain:
  == domain 1  score: 37.8 bits;  conditional E-value: 1e-12
  HTH_Tnp_Tc3_2   8 vrkdPritlreLanelkeeGksvsreTirrrLrkaglkkrkprkkplLskknrkaRLeFAkehln 72 
                     ++ +r+ + ++++el      + ++   r L+k g+  +k+ +kp+Ls ++++ RL++A+eh+n
     EEA19912.1 102 SKRTRRMPYYKVIREL---DLPIGATALARALKKRGYTRCKALRKPPLSDEHKRVRLAWALEHVN 163
                    5778888888999999...999999999***********************************97 PP

>> HTH_23  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.2   3.8e-06    0.0062       5      35 ..      37      67 ..      33      74 .. 0.91
   2 ?   -1.1   0.1       1.1   1.8e+03      34      41 ..     306     313 ..     304     320 .. 0.80
   3 ?   -4.0   0.0         9   1.5e+04       3      15 ..     351     363 ..     351     367 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 3.8e-06
      HTH_23  5 reRlrillllaeGlsvreIAreLgvsrrTvy 35
                ++R+ril l   G ++ +IA +L++++ +v+
  EEA19912.1 37 DDRIRILTLREAGFTYLQIASQLHITHDQVQ 67
                68*************************9998 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 1.1
      HTH_23  34 vyrwlkry 41 
                 v++w k +
  EEA19912.1 306 VWNWMKDW 313
                 9*****99 PP

  == domain 3  score: -4.0 bits;  conditional E-value: 9
      HTH_23   3 sereRlrilllla 15 
                 s++ R++++ l+ 
  EEA19912.1 351 SMQARCQAVILAE 363
                 5788999887765 PP

>> HTH_12  Ribonuclease R winged-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   1.4e-05     0.022       5      36 ..     112     142 ..     110     144 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.4e-05
      HTH_12   5 kilaesdkpigakeiaeeLkkrgydigeravR 36 
                 k++ e d piga ++a  Lkkrgy    +a+R
  EEA19912.1 112 KVIRELDLPIGATALARALKKRGYTR-CKALR 142
                 6999********************86.67777 PP

>> HTH_38  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.1   1.4e-05     0.023       4      31 ..      33      60 ..      31      64 .. 0.91

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 1.4e-05
      HTH_38  4 hLsleeReeIerllaeGlslreIArrLg 31
                +L+ ++R +I +l+++G ++ +IA +L+
  EEA19912.1 33 RLNRDDRIRILTLREAGFTYLQIASQLH 60
                8999*********************997 PP

>> DUF4350  Domain of unknown function (DUF4350)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.3   0.0     0.008        13       2      52 ..      13      66 ..      12      69 .. 0.76
   2 ?   -1.3   0.0       1.8     3e+03      46      60 ..      86     100 ..      82     101 .. 0.83
   3 ?    5.6   0.0     0.014        22       4      27 ..     120     144 ..     119     152 .. 0.84
   4 ?   -2.6   0.0       4.7   7.7e+03      30      46 ..     255     271 ..     244     283 .. 0.54

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.008
     DUF4350  2 kspnGtralaelLeaqGvevrrvrkp.fd..alegedgtllvvapdlrlteeel 52
                ++p+G+r +a+  e++ +++r  r+       l +++ t+l +a++l++t++++
  EEA19912.1 13 AAPEGAREAASGGESKPYSTRLNRDDrIRilTLREAGFTYLQIASQLHITHDQV 66
                68999999999999999999755554233345555677*************887 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.8
     DUF4350  46 rlteeelaallewva 60 
                  l+ee+++++ +w +
  EEA19912.1  86 KLSEEDVDRVIDWIS 100
                 6899********976 PP

  == domain 3  score: 5.6 bits;  conditional E-value: 0.014
     DUF4350   4 pnGtralaelLeaqGvev.rrvrkp 27 
                 p G+ ala+ L+++G++  ++ rkp
  EEA19912.1 120 PIGATALARALKKRGYTRcKALRKP 144
                 6799************986666665 PP

  == domain 4  score: -2.6 bits;  conditional E-value: 4.7
     DUF4350  30 alegedgtllvvapdlr 46 
                 +l + ++ +l + +d++
  EEA19912.1 255 RLNRQQSIYLQLMQDGN 271
                 44444555555555554 PP

>> HTH_32  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.0    0.0083        14      15      68 ..      16      65 ..      11      71 .. 0.74
   2 ?   12.8   0.6   8.8e-05      0.14      18      56 ..      76     130 ..      68     137 .. 0.66
   3 ?    2.6   0.7      0.13   2.1e+02      17      56 ..     130     173 ..     121     181 .. 0.67
   4 ?   -2.8   0.1       6.4     1e+04      53      60 ..     311     318 ..     306     336 .. 0.47

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0083
      HTH_32 15 egLkdrprrg..rpr..klsdevrariiallreeprWsprqlaarlaeregvkvShst 68
                eg ++++++g  +p   +l+ + r ri+ l+ e+  +++ q+a +l       + h +
  EEA19912.1 16 EGAREAASGGesKPYstRLNRDDRIRILTLR-EA-GFTYLQIASQL------HITHDQ 65
                566666666664553778*************.77.8********99......333433 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 8.8e-05
      HTH_32  18 kdrprrgrprklsdevrariiallreep.................rWsprqlaarl 56 
                  +++ rgr++kls+e ++r+i+++   +                   ++  la++l
  EEA19912.1  76 TPKKARGRTPKLSEEDVDRVIDWIS-SSkrtrrmpyykvireldlPIGATALARAL 130
                 588999******************4.332455444444444333333555555555 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.13
      HTH_32  17 Lkdrprrg........rprklsdevrariiallreeprWsprqlaarl 56 
                 Lk r   g        +p+ lsde+++  +a++ e+  W+ +q  + l
  EEA19912.1 130 LKKR---GytrckalrKPP-LSDEHKRVRLAWALEHVNWTIEQWNRIL 173
                 4444...222223341444.999999999999977889*999976655 PP

  == domain 4  score: -2.8 bits;  conditional E-value: 6.4
      HTH_32  53 aarlaere 60 
                  ++++e++
  EEA19912.1 311 KDWIQEQY 318
                 33443333 PP

>> HTH_33  Winged helix-turn helix
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.1     0.012        20      19      54 ..      58      93 ..      44      97 .. 0.85
   2 ?    6.4   0.1    0.0043         7      23      53 ..     122     152 ..     110     155 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.012
      HTH_33 19 gvsysvsgvyrlLkrlGfsyqkPrprapkqdpeaqe 54
                ++++++ +v    + +  +++k+r r pk ++e ++
  EEA19912.1 58 QLHITHDQVQYTCQSQQATPKKARGRTPKLSEEDVD 93
                567888999999999999**************9987 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.0043
      HTH_33  23 svsgvyrlLkrlGfsyqkPrprapkqdpeaq 53 
                   + + r Lk+ G++  k+ +++p  d++++
  EEA19912.1 122 GATALARALKKRGYTRCKALRKPPLSDEHKR 152
                 55677899********************986 PP

>> HTH_7  Helix-turn-helix domain of resolvase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.0    0.0056       9.1       7      37 ..      35      65 ..      33      66 .. 0.84
   2 ?    3.9   0.0     0.036        58       1      15 [.      82      96 ..      82     100 .. 0.94
   3 ?   -3.4   0.0       6.7   1.1e+04      21      35 ..     195     209 ..     193     210 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0056
                -HHHHGGGGSSTTTT--STTTSSSS---SSS CS
       HTH_7  7 skndinrvvkLleeGisiskIAkevnisRsT 37
                +++d  r+++L+e+G +  +IA ++ i+  +
  EEA19912.1 35 NRDDRIRILTLREAGFTYLQIASQLHITHDQ 65
                56666799*****************999655 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.036
                S---SS-HHHHGGGG CS
       HTH_7  1 GRpsklskndinrvv 15
                GR +kls++d +rv+
  EEA19912.1 82 GRTPKLSEEDVDRVI 96
                9************97 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 6.7
                 T--STTTSSSS---S CS
       HTH_7  21 GisiskIAkevnisR 35 
                 G+   +++ ++ ++R
  EEA19912.1 195 GEELDDTCLRTSVAR 209
                 666678899999998 PP

>> DUF2774  Protein of unknown function (DUF2774)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00021      0.35       3      31 ..      39      67 ..      37      83 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00021
     DUF2774  3 kvqvhflhesgknFveIAkkldirakdva 31
                ++++ +l+e+g+ + +IA +l i+  +v 
  EEA19912.1 39 RIRILTLREAGFTYLQIASQLHITHDQVQ 67
                578999*****************988775 PP

>> Sigma70_r4_2  Sigma-70, region 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00033      0.54      17      40 ..      41      63 ..      32      69 .. 0.77
   2 ?   -2.3   0.3       2.3   3.8e+03      45      53 ..     124     132 ..     123     132 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00033
                  HHHHHHHTS---HHHHHHHHT--H CS
  Sigma70_r4_2 17 eifllryleglsykEIAellgise 40
                  +i++l ++ g++y +IA++l+i+ 
    EEA19912.1 41 RILTL-REAGFTYLQIASQLHITH 63
                  46666.89*************985 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 2.3
                   HHHHHHHHH CS
  Sigma70_r4_2  45 srlsRArkk 53 
                   ++l+RA+kk
    EEA19912.1 124 TALARALKK 132
                   6799***98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (369 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       577  (0.0321825); expected 358.6 (0.02)
Passed bias filter:                      455  (0.0253779); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.41
# Mc/sec: 2677.69
//
Query:       EEA19913.1  [L=374]
Description: alpha-ketoglutarate-dependent taurine dioxygenase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.4e-49  167.7   0.0    5.3e-49  167.4   0.0    1.1  1  TauD      Taurine catabolism dioxygenase TauD, TfdA family


Domain annotation for each model (and alignments):
>> TauD  Taurine catabolism dioxygenase TauD, TfdA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  167.4   0.0   2.9e-53   5.3e-49       3     267 ..      80     352 ..      78     353 .. 0.89

  Alignments for each domain:
  == domain 1  score: 167.4 bits;  conditional E-value: 2.9e-53
        TauD   3 kpltpkfgae..gvdlsdleslddelkeelrellaeygvvvfrgfpl...speqqlefarrfGplygtpgrgtntkygevld..vssvyesadian.la 93 
                  +++p++g    gv+l++   l+d+ k+el  l+ae++vv f++++l    pe+q +f+r fG+   +p +g+ + y++ ++  ++ + ++ ++     
  EEA19913.1  80 SHIQPCIGSIveGVQLNK---LSDAAKDELALLIAERKVVAFPDQDLidaGPEEQYSFMRHFGKPNYQPISGSMKGYPGFHIihRDGNVDEINRFLeQR 175
                 678888999866777777...88899*************************************9999999************65333333333333344 PP

        TauD  94 yttllwHtDlsylesppgiqlLhcleapatGGetpfvDgraaynaLpeelpellegltavrvyyhyrggglrteqelpavdkhprtghpvvrthpvltg 192
                 +tt lwH D sy+ +pp +++L  l+ p  GG+t f+ + aay++L+++ ++++++l+av++ ++++       +    +++  ++ hp+vr+hpv tg
  EEA19913.1 176 TTTTLWHQDVSYEIQPPAYVMLGLLQGPDVGGDTVFAATDAAYKRLSPTFQSFIDNLKAVHTSAKMIA--HARLTGGLVRKDPVESVHPLVRVHPV-TG 271
                 55666***************************************************************..77777777788888999********8.** PP

        TauD 193 rkallvnppfatrieglgtpeskelldaleelledp.eftyrfqwqeGdlvifdNrrvlHgrt.af...deg.eeRhllrc 267
                 +k+l++n  f t+i+gl++pe++ l d+l ++l    +f+ r++wq+  +v+fdNr++ H++  ++   d g ++Rh+ r+
  EEA19913.1 272 EKCLFINGEFITKIQGLKEPEFRVLQDFLMQHLITGhDFQARVRWQPRTVVMFDNRSTIHSAIvDYldeDHGaKPRHIFRL 352
                 ***********************************56*****************************965222467999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (374 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       331  (0.0184617); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2697.77
//
Query:       EEA19914.1  [L=566]
Description: extracellular lipase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.3e-81  273.7   0.0    4.2e-81  273.3   0.0    1.0  1  COesterase     Carboxylesterase family
      3e-05   24.0   0.2       0.16   11.8   0.0    2.2  2  Abhydrolase_3  alpha/beta hydrolase fold


Domain annotation for each model (and alignments):
>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  273.3   0.0   4.7e-85   4.2e-81      10     509 ..      40     554 ..      31     557 .. 0.84

  Alignments for each domain:
  == domain 1  score: 273.3 bits;  conditional E-value: 4.7e-85
                 EEEEEEEEEESTCSEEEEEEEEESSB---GGGTTS--BE----SSEEECBS---BESEECSSSSSCGHHCHHH..............BES---EEEEEE CS
  COesterase  10 GkvrGkrvklksekevdaFlGiPYAepPvgelRFkkPepaepwtgvrdAtkfspaCpqnaeksekeekeleaw..............vsEDCLyLnvyt 94 
                  ++ G +       +vd+F GiP+A+pP+g+lR k+P++ ++  g + At  +++Cpq     + ++ +                    EDCL++nv  
  EEA19914.1  40 ATIVGASSG-----TVDVFNGIPFAKPPTGPLRLKPPVALTSGLGKVTATGIAQSCPQMFFSDSLNSLT-GILgtlinlpllqditdAGEDCLTVNVIR 132
                 555555555.....9************************99999**************98666665543.3336899********************** PP

                 ESSSSSTTSSEEEEEEE--STTTS-BGCGS-THHHHHHH.....TSEEEEE----HHHHH-B-SS..TTSBS-HHHHHHHHHHHHHHHHGGGGTEEEEE CS
  COesterase  95 PkekkeakkklPVlVwihGggfqtgsaseydgsaLaaeg.....nvivVtinYRlGvlGFlstgd..eeapGNvGllDqvlALrWVkenIasFGGdper 186
                 Pk +   ++klPVl+wi+Gggf+ g  s+ydg++++++       +i V++nYR+G +GFl+ ++   + + N+GllDq+l L+WV +nIa+FGGdp +
  EEA19914.1 133 PKGA-GPTSKLPVLFWIFGGGFELGGTSTYDGTSIVENAiakgtPIIFVAVNYRVGGFGFLAGKEilADGSSNLGLLDQRLGLQWVADNIAQFGGDPTK 230
                 *996.788888*************************999999999******************996677777*************************** PP

                 EEEEEETHHHHHHHHHHHSGGGTT......SBSEEEEES--TTSTTTSBSH.HHHHHHHHHHHTTS-CSSHHHHHHHHHCS-HHHHHHCCGG..SSSSS CS
  COesterase 187 vtlfGesAGaasvsllllsplsrg......lfkraIlqSGsalspwaiqkk.arkrakklakkvgckassskelveclrsksaeelldaqek..aleas 276
                 vt++GesAG+ sv  ++l     +      lf+ aI+ SGs +    ++   a+k+ + + +++gc  s ++++++clr  ++++ l+a ++  ++   
  EEA19914.1 231 VTIWGESAGSISVLDQMLLYDGDNtykgqpLFRGAIMDSGSIVPTNPVDGGaAQKVYDSVVSAAGC--SRASDTLNCLRGLDYTTYLNAANSvpGILSY 327
                 *************98888755554456677*************9999999989999**********..788899****************999977788 PP

                 STTC-SSS-B--SSSSSS-HHHHHHCGC..CSEEEEEEETTTTHHHHCCHSTTTSSSSHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHS....... CS
  COesterase 277 ssklvsfaPvvdgdflpekPeellkseg..kvplliGvnkdegllflaylldkeksvkkkeeklsesllkdelyleaekkeelseaikeeyt....... 366
                 +s  +s  P  dg++l+++Pe l+k+ +  +vp++iG  +deg+lf+ ++ +         +++++  + +++++   +++++ e + + y        
  EEA19914.1 328 NSVALSYLPRPDGKILTDSPEILVKNGKyaPVPMIIGDQEDEGTLFALFQSNL-------TTTQQVIDYLQNVFFSYDGNKTIVEGLVKAYPddatfgs 419
                 8899999*******************88*******************965443.......223333333344444444466666666666655555666 PP

                 ..TTTSSTCHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHTT-S.....EEEEEEE--STTSSSTTTGSSBTTTTHHHHTTGGGTSGCSS-HHHHHHHHH CS
  COesterase 367 ..deadrddaeksrkallelltdvlfkapvlrtaklhasrgsp.....vYlYsfdyrnssskkpkwmgvvhgdeleyvfglpllekeeftkedeklsrk 458
                    + +r++    +k+l+++l+d++f++  +++++l  ++ +p      Yl s+dy +      + +g+ hg+++  vf   +  ++         s+ 
  EEA19914.1 420 pfRTGTRNNWYPQYKRLAAILGDAVFTLTRRAFLNLA-NAANPsipswSYLSSYDYGT------PIIGTGHGTDILQVFYGIVP-DY--------ASAA 502
                 6577888888889999**************9999999.55554456556666677766......59*************76665.44........599* PP

                 HHHHHHHHHHHSSTTS.TTSS----B.TTTBEEEEESSSSS.EEEESTTHHHH CS
  COesterase 459 mmtywtnFaktgnPnk.eeeekWpkytkeeekylkinlkpk.rvkkklkeeev 509
                 + +y  +F+++ +Pn  ++ ++Wp+  +  +k++++n +   ++++  +++++
  EEA19914.1 503 IWSYYLSFIYNLDPNAnTTYPAWPRW-STGNKLINFNANSAaTITDDFRQTQY 554
                 ***************98999******.66677777777765456666666665 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.1   0.0     6e-05      0.54       2      39 ..     146     186 ..     145     188 .. 0.84
   2 !   11.8   0.0   1.8e-05      0.16      56      82 ..     214     240 ..     206     271 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 6e-05
                    EEE--STTTS--TTTT..HHHH.HHHHHHHTSEEEEEE--- CS
  Abhydrolase_3   2 vyfHGGGfvlgsldth..dalc.relakelgavvvsvdYrl 39 
                    +++ GGGf lg+ +t+  ++++ + +ak + ++ v+v+Yr 
     EEA19914.1 146 FWIFGGGFELGGTSTYdgTSIVeNAIAKGTPIIFVAVNYRV 186
                    7899************7644442689**************6 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 1.8e-05
                    HHHHHHTHHHHTETTCEEEEEEETHHH CS
  Abhydrolase_3  56 lrwlaeqawelgadpsrivlaGdSaGG 82 
                    l+w+a++ +++g dp+++++ G+SaG 
     EEA19914.1 214 LQWVADNIAQFGGDPTKVTIWGESAGS 240
                    89*****99****************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (566 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       298  (0.0166211); expected 358.6 (0.02)
Passed bias filter:                      262  (0.0146132); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3919.97
//
Query:       EEA19915.1  [L=411]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (411 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       472  (0.0263261); expected 358.6 (0.02)
Passed bias filter:                      449  (0.0250432); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 2685.38
//
Query:       EEA19916.1  [L=444]
Description: hypothetical protein PMAA_006830 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (444 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       688  (0.0383736); expected 358.6 (0.02)
Passed bias filter:                      454  (0.0253221); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.47
# Mc/sec: 2861.30
//
Query:       EEA19917.1  [L=310]
Description: enoyl-CoA hydratase/isomerase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.7e-39  133.5   0.0    9.9e-39  133.1   0.0    1.1  1  ECH_1     Enoyl-CoA hydratase/isomerase
    4.3e-29  102.1   0.0    6.1e-27   95.0   0.0    1.9  2  ECH_2     Enoyl-CoA hydratase/isomerase


Domain annotation for each model (and alignments):
>> ECH_1  Enoyl-CoA hydratase/isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  133.1   0.0   1.1e-42   9.9e-39       4     250 ..      32     286 ..      29     287 .. 0.93

  Alignments for each domain:
  == domain 1  score: 133.1 bits;  conditional E-value: 1.1e-42
                 TTEEEEEE--CGCTTEE-HHHHHHHHHHHHHHHHSTTECEEEEEEBTSEEEEEB-HHHHHHHHC.......HHHHHHHCCHHHHHHHHHHSSSEEEEEE CS
       ECH_1   4 agvaviklnrPeavNalsaelltEliqalekleddksvravvLtGgdkaFaaGadlkemaeeek.......akqallkeevlelwtklytvpkpviaav 95 
                   v+++klnrP++ Na+++e+++Eli a +++e d  +++vv+tG++ aF+aGadl+              +k ++ +        ++ ++ kp+i a+
  EEA19917.1  32 TKVVLLKLNRPRQFNAVTNEMIEELITAYKYFEADDRIKVVVVTGSGPAFCAGADLRVGFSTLLddvkkdpSKIESHRDGGGRVALAIHNCSKPTIMAI 130
                 67999**************************************************9987654333221222566667777778899************* PP

                 -SEEETHHHHHHHHSSEEEEETTTEEE-GGGGGTS--CTTCHHHHHHHHHHHHHHHHHHHT-EEEHHHHHHCTSSSEEESG.GGHHHHHHHHHHHHHHS CS
       ECH_1  96 nGaaigGGlelalacDiviaadnasfglnelklGlipgaggtqilarkvGkskAeeilllgkkisaqealkvGlvdkvvpe.eqlleealelaeklaek 193
                 nG a+g G+ l l + i++a  +++++ ++++ Gl  +a+ +++l++ vG s+A ++l +g  + a + l   l + ++p  ++ +  al++ae +a +
  EEA19917.1 131 NGPAVGFGITLTLPATIRVACASSKISFAFSRRGLSMEACSSFFLPKLVGTSRALHLLTTGATYLASDPLLSNLFSDILPTpQETVASALKIAEDIAAN 229
                 *********************************************************************************9999************** PP

                 CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTSHHHHHHHHHHHTCSH----- CS
       ECH_1 194 spaalrqlkealnakledalaeqleaeaklfestfskddikeGlqaflEkrkpefed 250
                  +++   ++  l   + +  +e+  +e+klf  +  ++d+ eG+++fl kr+ +f++
  EEA19917.1 230 TSTVSTKVMRDLIYRAPRSVEEAHLLESKLFLRMLISKDSAEGMKSFLQKRNVDFRG 286
                 *****************99999999********99999***************9986 PP

>> ECH_2  Enoyl-CoA hydratase/isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.0   0.0   6.8e-31   6.1e-27       3     174 ..      36     211 ..      34     225 .. 0.89
   2 !    5.5   0.1    0.0012        11     250     311 ..     220     280 ..     211     290 .. 0.82

  Alignments for each domain:
  == domain 1  score: 95.0 bits;  conditional E-value: 6.8e-31
                 EEEE--GGGTT-B-HHHHHHHHHHHHHHCC-TT-SEEEEEESSSSECE--B--HHHHHHHHCS...-THH.HHHHHHHHHHHHHHHC-SS-EEEEE-BE CS
       ECH_2   3 vitLnrpkalNaLslemvralkealkewekddevklvvlkgagekafCAGgDvralyeaakeg...kkee.eeffreeYklnyliatypkpvvalmdGi 97 
                 +++Lnrp+++Na++ em+++l  a+k +e+dd++k+vv++g+g  afCAG D+r   ++  ++   + ++ e+      ++  +i++++kp++  ++G 
  EEA19917.1  36 LLKLNRPRQFNAVTNEMIEELITAYKYFEADDRIKVVVVTGSG-PAFCAGADLRVGFSTLLDDvkkDPSKiESHRDGGGRVALAIHNCSKPTIMAINGP 133
                 689**************************************88.8*********9888888874322223577777889******************** PP

                 EETHHHHHHTTSSEEEE-TT-EEE--GGGGT----TTHHHHHHCSST.THHHHHHHH---B-HHHHHHTTS--EE--G CS
       ECH_2  98 vmGgGvGlsvhgsfrvvtertvfAmPEtaIGlfPDvGgsyfLsrlpg.elGlylalTGarlkgadalaaglathyvps 174
                 ++G G+ l++ +++rv++ +++++    + Gl  +   s+fL++l g + +l+l  TGa+  ++d l  +l + ++p+
  EEA19917.1 134 AVGFGITLTLPATIRVACASSKISFAFSRRGLSMEACSSFFLPKLVGtSRALHLLTTGATYLASDPLLSNLFSDILPT 211
                 *********************************************77588*************999999888877776 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.0012
                 HHHHHHHH.HS-HHHHHHHHHHHHHHTTT--HHHHHHHHHHHHHHHHHHSSHHHHHHHHTTS- CS
       ECH_2 250 kktletlk.krsPtslkvtleqlrrgrklsslaevlrmElrlalrllaekDfveGvrallvdk 311
                  k++e ++ + s +s kv+  ++ r+ +   ++e+   E +l lr+l +kD +eG ++ l ++
  EEA19917.1 220 LKIAEDIAaNTSTVSTKVMRDLIYRAPRS--VEEAHLLESKLFLRMLISKDSAEGMKSFLQKR 280
                 45555555267899999999999999987..8************************9988655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (310 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       431  (0.0240393); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2159.49
//
Query:       EEA19918.1  [L=237]
Description: hypothetical protein PMAA_006850 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (237 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       336  (0.0187406); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.25s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1600.23
//
Query:       EEA19919.1  [L=162]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.5e-10   39.7   0.0    5.3e-10   39.4   0.0    1.0  1  Bys1      Blastomyces yeast-phase-specific protein


Domain annotation for each model (and alignments):
>> Bys1  Blastomyces yeast-phase-specific protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.4   0.0     3e-14   5.3e-10       9     144 ..      20     156 ..      13     162 .] 0.82

  Alignments for each domain:
  == domain 1  score: 39.4 bits;  conditional E-value: 3e-14
        Bys1   9 dlgsafvlvycnfsvaldveagevstrkildgrsydyynekyrggsgdgvsltlsht.egrdssnsettfrykladdnstveyslgnsggnpfeghklt 106
                  +g+a v+  c+ sv+l v    v    il+   +  y e  r+  g g+ + ++   +g  s   +  f y +  +   v y l n  g+pfeg  ++
  EEA19919.1  20 AIGNAAVINNCDRSVYLWVIDPAVGQEIILEP--HSSYIEMIRPSPG-GIEFKITEIpHGLFSNSPRLIFTYDMNYG--EVWYGLCNLFGDPFEGDEVA 113
                 68***********************9999986..5678999999776.777777665156666667999***99765..699*************9876 PP

        Bys1 107 ...lkssddrcpriewpegiptgvs..sgscgssenliltlcp 144
                    +++++ +c  + wp+g+p g    +  cg + +l l lc 
  EEA19919.1 114 vipINPTGHSCDVLRWPNGLPPGGQtpATMCGENTDLHLNLCG 156
                 22268899*************9865125789**********94 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (162 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       374  (0.0208601); expected 358.6 (0.02)
Passed bias filter:                      352  (0.019633); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.44
# Mc/sec: 1100.36
//
Query:       EEA19920.1  [L=295]
Description: hypothetical protein PMAA_006870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (295 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       450  (0.025099); expected 358.6 (0.02)
Passed bias filter:                      204  (0.0113782); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.24s 00:00:00.70 Elapsed: 00:00:00.41
# Mc/sec: 2173.03
//
Query:       EEA19921.1  [L=126]
Description: hypothetical protein PMAA_006880 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.3e-12   46.9  13.8    4.3e-12   46.5  13.8    1.2  1  Hydrophobin  Fungal hydrophobin


Domain annotation for each model (and alignments):
>> Hydrophobin  Fungal hydrophobin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.5  13.8   2.4e-16   4.3e-12       1      80 []      36     122 ..      36     122 .. 0.80

  Alignments for each domain:
  == domain 1  score: 46.5 bits;  conditional E-value: 2.4e-16
  Hydrophobin   1 C.ntgevqCCnsvqkakdssavkkllgllglelkdlt..gqvgltCspin..vvgvgggssC.tqqpvCCennsfnglin..lgCtpi 80 
                  C ++++v+CC++v+++++s +v + l++ g++ +d +  gqvgltC+pi+  ++    g+ C  + ++CCen+s++gl+n  lgCt i
   EEA19921.1  36 CsAGTSVHCCDTVDSTDNS-NVLNQLNAAGIDHSDAKqkGQVGLTCTPITtsLIDAINGNVCqGAVTACCENTSQTGLVNlnLGCTII 122
                  756788********88665.66667788888777766559*********7556777779***446689***********9889**976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (126 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       659  (0.0367561); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.34u 0.24s 00:00:00.58 Elapsed: 00:00:00.37
# Mc/sec: 1015.97
//
Query:       EEA19922.1  [L=441]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-23   83.3   0.4      2e-23   82.7   0.4    1.3  1  DUF3425   Domain of unknown function (DUF3425)
      0.002   18.2   9.9      0.037   14.1   5.3    2.3  2  bZIP_1    bZIP transcription factor
      0.003   17.6  14.5      0.055   13.6   4.4    2.4  2  bZIP_2    Basic region leucine zipper
  ------ inclusion threshold ------
       0.19   10.3   0.0       0.26    9.9   0.0    1.1  1  GP120     Envelope glycoprotein GP120


Domain annotation for each model (and alignments):
>> DUF3425  Domain of unknown function (DUF3425)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.7   0.4   4.4e-27     2e-23       1     123 [.     303     427 ..     303     428 .. 0.94

  Alignments for each domain:
  == domain 1  score: 82.7 bits;  conditional E-value: 4.4e-27
     DUF3425   1 ddlprfpispseeaveklpenlrPtelQlriaHpveidvlpwpelRdrllrafqeeeidedeffrdvvs.tlivWsieeeelet.....aeissaelsa 93 
                 +++++++ +p+ +++++l ++ +P ++Ql+ +H   id+++wp++R +++r++ +  +d  e+f+ +   ++++W++++++le+     +++++++ + 
  EEA19922.1 303 YNYSKWRAAPTPATFARLAPFQHPLPIQLEQDHFGGIDMIVWPQMRVNMIRHWGK--VDLLEVFDFLSAcMKVRWPWNKDMLERdaddnLQLREDFRQI 399
                 6799***********************************************9988..999999998854499*********9999**9999999**999 PP

     DUF3425  94 gdvtdlegWelkesFfrkYpylvdglelei 123
                   + +++gW l+ +F+++Yp+l++g+++e 
  EEA19922.1 400 --FSSEAGWGLTAEFIDRYPMLLEGMDVEA 427
                 ..***********************99986 PP

>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.1   5.3   8.2e-06     0.037       7      36 ..      14      43 ..      12      50 .. 0.91
   2 !    6.0   0.1    0.0028        12      28      56 ..      71      99 ..      69     104 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 8.2e-06
                XXXX--HHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  7 ekrkqkNReaArrsRqRKqaeieeLerrvk 36
                ek++++ R a++  R+++q ++ eLe+rv 
  EEA19922.1 14 EKKRLRDRKAQQTLREKRQNRMLELETRVT 43
                8***************************96 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.0028
                HHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1 28 ieeLerrvkaLekeNksLkseleelkkev 56
                + +L + v+ L  eN  L+++ e+l+ +v
  EEA19922.1 71 MTKLLDTVERLRLENNRLRERQESLRRMV 99
                5678899*****************99886 PP

>> bZIP_2  Basic region leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.6   4.4   1.2e-05     0.055       4      39 ..      12      47 ..       9      48 .. 0.88
   2 !    9.2   2.5   0.00027       1.2      27      53 ..      71      97 ..      69      98 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 1.2e-05
                XXXXXXXXXXXXXXX-HHHHHHHHHHHHHHHHHHHH CS
      bZIP_2  4 eyrerRrkNreAarrsRekkkakeeeleervkeLee 39
                +++++R + r A ++ Rek+  ++ ele rv + e+
  EEA19922.1 12 SSEKKRLRDRKAQQTLREKRQNRMLELETRVTFCEK 47
                4566777************************99876 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00027
                HHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_2 27 eeeleervkeLeeeNaqLrqkveqLek 53
                + +l ++v++L+ eN++Lr+++e+L++
  EEA19922.1 71 MTKLLDTVERLRLENNRLRERQESLRR 97
                5677899*****************985 PP

>> GP120  Envelope glycoprotein GP120
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0   5.7e-05      0.26     326     406 ..      21     105 ..       5     157 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 5.7e-05
                 HHHHHHHHHH.....SHSTSEEEE.HHHTTBSHHHHTEEEEETTEEEEECTTTTS-HHH....HHHHHHHXEEEEESEEEGSSSS CS
       GP120 326 kevksklveqprykgindtkkiiftkqsaGsdpevvtmstncrGeflycnstqllnwve....dknqtersycrikqiintwqkv 406
                 ++ +++l+e+ + + ++ + ++ f+ ++ G+d +v +  ++  Ge    ++t+ll+ ve    ++n+ +  +  +++++  w+  
  EEA19922.1  21 RKAQQTLREKRQNRMLELETRVTFCEKNHGGDAQVKLDPVQDEGESQALDMTKLLDTVErlrlENNRLRERQESLRRMVGSWDSS 105
                 56789*****99999999**************************************87733334566666677888888888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (441 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       613  (0.0341904); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3079.03
//
Query:       EEA19923.1  [L=537]
Description: MFS multidrug transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.6e-47  161.5  32.7    2.6e-47  161.5  32.7    1.5  1  MFS_1     Major Facilitator Superfamily
    1.1e-08   34.4  21.5    5.8e-08   32.0  21.4    2.1  1  Sugar_tr  Sugar (and other) transporter
     0.0028   16.0   1.3     0.0028   16.0   1.3    2.2  3  OATP      Organic Anion Transporter Polypeptide (OATP) family
  ------ inclusion threshold ------
       0.31   10.3  19.6       0.01   15.2  10.2    2.6  3  MFS_4     Uncharacterised MFS-type transporter YbfB


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  161.5  32.7   5.9e-51   2.6e-47       4     352 ..     100     487 ..      97     492 .. 0.81

  Alignments for each domain:
  == domain 1  score: 161.5 bits;  conditional E-value: 5.9e-51
       MFS_1   4 aaflsalarsilgpalplalaedlg.ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgaga 101
                 ++++s la+s+++pal+   a d++  +++ +++ +t+y lg+ ++ l+l++ls+ +Grr vl ++  +f+++ + +++++++ +l+v+r+l+G+g+++
  EEA19923.1 100 MTLVSPLASSMFAPALT-SAAADFHvTNVTLLSFSVTIYLLGYTFGPLVLAPLSEIYGRRIVLSCANWFFVVWQIGCALSPNISALIVFRLLAGIGGSG 197
                 7899*************.9999*99566777******************************************77677779999*************** PP

       MFS_1 102 lfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee............ 188
                  +++ga +iad+fp +er+ra++l+s+g  lG++ gp+ gg++ + +gWr+v+++l iv+  + v  ++ ++ +++  +    ++ e            
  EEA19923.1 198 CITLGAGVIADLFPMRERARATALWSMGPLLGPVAGPICGGFIGETIGWRWVYWLLLIVAGALSV--GIEILNRETYARVLIRWKMEklakelgrddlr 294
                 ***************************************************************88..35555555555555555555567777777777 PP

       MFS_1 189 ...........kgtgpaplvp...awkallkdpvlw....illialllfffgfsg...lltllplylqevlgls.glllaglllallalvgailallag 265
                             +t      p   +++ l+++  l+    i+++ ++++++++ +   ++t++p  + +++++s g l+++++++++a ++++  +++g
  EEA19923.1 295 sgyeseqqsrnRQT------PgqvLIQGLKRPVILFckspIVFLLCIYMSLVYGLlylFFTTIPAVFETQYNFSpG-LSGLAYIGIGAGFFLG-LIIVG 385
                 77777655443222......133344455555544355444444444444444445559999**999*******86.6666556666655544.599** PP

       MFS_1 266 rlsdr............lgrrrrlllallllllaalglallavtssavllllvlvl....iGfglgfvfpsllalasdlappeeagtasglfntagslg 348
                    dr            + ++ rl  ++++ ++a +++++ +++ +++++++v ++    +G+++   f ++++++ d++   +a++a++  + ++sl 
  EEA19923.1 386 TTNDRivlkmmknnggkYEPEMRLPTMIIFSAIAPISFFWYSWSADKHVHWIVPIIgmfpYGLAMMGLFLPIQTYVIDSYQ-TYAASAVACLTATRSLF 483
                 *9*******99999999999************************9*****9977777777999777778888888888885.78888888888888877 PP

       MFS_1 349 galg 352
                 gal 
  EEA19923.1 484 GALL 487
                 7765 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.0  21.4   1.3e-11   5.8e-08      44     209 ..     126     287 ..      94     524 .. 0.69

  Alignments for each domain:
  == domain 1  score: 32.0 bits;  conditional E-value: 1.3e-11
                 ...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHH CS
    Sugar_tr  44 ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvsl 142
                   +l++++v i+l+G ++G l++ +l++++GR+ +l +a+ +fv+ ++ +a+++   ++ +liv R+l+Gig  ++ +l    i+ + p + R + + l
  EEA19923.1 126 NVTLLSFSVTIYLLGYTFGPLVLAPLSEIYGRRIVLSCANWFFVVWQIGCALSP---NISALIVFRLLAGIGGSGCITLGAGVIADLFPMRERARATAL 221
                 5678999***********************************************...****************9999999******************9 PP

                 HHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHG.GGS---HHHHHHTT-HH.HHHH CS
    Sugar_tr 143 yqlaitfGilvaaifglglnktsnadgwrillglqlvpallllill.lflPESPrylvekgkee.eake 209
                 + ++  +G + + i+g ++ +t +   wr+  +l l+ a +l++++ ++ +E+    +++ k e  ake
  EEA19923.1 222 WSMGPLLGPVAGPICGGFIGETIG---WRWVYWLLLIVAGALSVGIeILNRETYARVLIRWKMEkLAKE 287
                 999999999999999988888877...*****************9966667884333333333323333 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.1       0.5   2.2e+03     169     200 ..      93     124 ..      86     134 .. 0.80
   2 !   16.0   1.3   6.3e-07    0.0028     135     354 ..     184     387 ..     162     400 .. 0.70
   3 ?   -3.1   0.3      0.38   1.7e+03     502     518 ..     506     522 ..     497     524 .. 0.70

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 0.5
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 169 ylgilyalrilGpalGfllGslllklyvdids 200
                 +l+++++++++ p    +++ +l++   d++ 
  EEA19923.1  93 LLALMSSMTLVSPLASSMFAPALTSAAADFHV 124
                 57899999999999999998888888888754 PP

  == domain 2  score: 16.0 bits;  conditional E-value: 6.3e-07
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 135 fflaqlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllklyvdidseisltpkdprWvgaWWlgflilgvllllaaipl 233
                 +++  ll+GiG++  +tlG   i D    ++ +   +++++  +lGp+ G ++G+++ ++   i            W   +Wl  +++g+l + + i+ 
  EEA19923.1 184 LIVFRLLAGIGGSGCITLGAGVIADLFPMRERARATALWSMGPLLGPVAGPICGGFIGET---I-----------GWRWVYWLLLIVAGALSVGIEILN 268
                 566689*************************************************88872...3...........477779*********999999774 PP

                 .xxxxxxxxxxxxxxxxxxxxxxxx.....x...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 234 .ffFPkelpkkkeerakkkseeesa.....e...kkeekkkkeksksseeeelkslkdfpkalkrllknpifllvilssvfeillvaGfitFlpkylEt 323
                    + + l      r k ++ +++      +   ++e+++ ++++          ++ + + +   +k+pi +l+++   + + l+  f+t +p   Et
  EEA19923.1 269 rETYARVLI-----RWKMEKLAKELgrddlRsgyESEQQSRNRQTP-----GQVLIQGLKRPVILFCKSPIVFLLCIYMSLVYGLLYLFFTTIPAVFET 357
                 134555543.....22222222222222122221222222222222.....23467777778888999999999888888888888899999******* PP

                 xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxx RF
        OATP 324 qFslsaseAnllt.GvvvipgaalGillgGll 354
                 q++ s+  + l   G+    g+ lG+++ G  
  EEA19923.1 358 QYNFSPGLSGLAYiGI--GAGFFLGLIIVGTT 387
                 *****99887752022..23445555555554 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 0.38
                 xxxxxxxxxxxxxxxxx RF
        OATP 502 lllirllgliPgPiifG 518
                 ll +  l+++P Pi+f 
  EEA19923.1 506 LLGFVALAFVPIPILFT 522
                 44455789******995 PP

>> MFS_4  Uncharacterised MFS-type transporter YbfB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2  10.2   2.2e-06      0.01      14     162 ..     113     261 ..      87     276 .. 0.79
   2 ?    1.2   0.1     0.041   1.8e+02      79     139 ..     326     386 ..     296     398 .. 0.71
   3 ?   -2.3   0.3      0.47   2.1e+03     199     225 ..     445     472 ..     426     513 .. 0.56

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 2.2e-06
       MFS_4  14 piLPallaegqls.lsqagllaaaNylGYLvGallaafalsagaeRlrllagllatvllllamaltesfaaflliRflaGvasAvvlvfgsslvlahaa 111
                 p L    a+ +++ ++ +++  ++ +lGY  G l+ a   +    R++l ++ +  v+  + +al  +++a+++ R+laG+++   + +g+ ++     
  EEA19923.1 113 PALTSAAADFHVTnVTLLSFSVTIYLLGYTFGPLVLAPLSEIYGRRIVLSCANWFFVVWQIGCALSPNISALIVFRLLAGIGGSGCITLGAGVIADLFP 211
                 5555555555554245567778999*********99888888899999**********************************************99999 PP

       MFS_4 112 aarrervgallfaGvGlGiavsgllvllllqlglsassl.Wlalavlsavll 162
                   +r+r  al   G+ lG +++ ++  ++  +  ++ ++ Wl+  +++ +l 
  EEA19923.1 212 MRERARATALWSMGPLLGPVAGPICGGFIG-ETIGWRWVyWLL-LIVAGALS 261
                 99999999*9999**999877766654433.333344441443.33333333 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.041
       MFS_4  79 esfaaflliRflaGvasAvvlvfgsslvlahaaaarrervgallfaGvGlGiavsgllvll 139
                 +s ++fll  +++ v + + l f++  ++ +++   ++ + +l + G+G+G  ++ ++v  
  EEA19923.1 326 KSPIVFLLCIYMSLVYGLLYLFFTTIPAVFETQYNFSPGLSGLAYIGIGAGFFLGLIIVGT 386
                 555555555555556666677777777788889999999************9998777755 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 0.47
       MFS_4 199 aYglaGfGY.iitatFlvaiardgagga 225
                  Ygla +G+  ++ t++++  ++ a++a
  EEA19923.1 445 PYGLAMMGLfLPIQTYVIDSYQTYAASA 472
                 4555555531333455554444433332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (537 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       759  (0.0423336); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.30s 00:00:00.93 Elapsed: 00:00:00.44
# Mc/sec: 3638.08
//
Query:       EEA19924.1  [L=269]
Description: DUF1445 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.9e-34  117.3   0.3    1.5e-16   60.7   0.0    2.2  2  DUF1445   Protein of unknown function (DUF1445)


Domain annotation for each model (and alignments):
>> DUF1445  Protein of unknown function (DUF1445)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.7   0.0   8.2e-21   1.5e-16       1      52 [.     145     196 ..     145     199 .. 0.95
   2 !   55.1   0.1   4.1e-19   7.4e-15      99     143 .]     200     249 ..     197     249 .. 0.93

  Alignments for each domain:
  == domain 1  score: 60.7 bits;  conditional E-value: 8.2e-21
     DUF1445   1 VaFliGcSfsfeeaLleaglpvrhveqgrnvpmYktniplapagvfsgklvv 52 
                 +aFliGcSfsfe+aL++agl + h+e++r+v+mY+t+ipl pag f+g+  v
  EEA19924.1 145 IAFLIGCSFSFEQALAQAGLRICHQEDSRTVAMYQTSIPLLPAGIFHGSSYV 196
                 69**********************************************9665 PP

  == domain 2  score: 55.1 bits;  conditional E-value: 4.1e-19
     DUF1445  99 GdaveieegevPvFWacgvtpqeavmsa....kl.elvithapghmlvtD 143
                 Gda++++egevPvFW+cgvtpq av++a     + ++v++h+pghmlvtD
  EEA19924.1 200 GDAQVVREGEVPVFWGCGVTPQFAVEKAlerdAIaGTVMSHKPGHMLVTD 249
                 9************************99988765679*************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (269 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       323  (0.0180155); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1812.02
//
Query:       EEA19925.1  [L=642]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.1e-10   40.6   1.0    3.8e-10   39.8   0.5    1.7  2  DUF659         Protein of unknown function (DUF 659)
    3.2e-06   26.8   0.1    1.1e-05   25.2   0.1    1.9  1  Dimer_Tnp_hAT  hAT family C-terminal dimerisation region
  ------ inclusion threshold ------
      0.065   12.8   0.1       0.12   11.9   0.1    1.4  1  DUF2110        Uncharacterized protein conserved in archaea (
       0.23   12.0   6.9       0.87   10.1   6.9    2.0  1  APG6_N         Apg6 coiled-coil region


Domain annotation for each model (and alignments):
>> DUF659  Protein of unknown function (DUF 659)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.8   0.5   8.6e-14   3.8e-10       1     144 [.     123     275 ..     123     288 .. 0.82
   2 ?   -3.5   0.0       1.9   8.5e+03      94     125 ..     317     348 ..     308     352 .. 0.60

  Alignments for each domain:
  == domain 1  score: 39.8 bits;  conditional E-value: 8.6e-14
      DUF659   1 PsseeLrgtlLqeeveeikkkvkeikkswektgcsillDgwtdkkgrslinflvscpkGtvFlksvdassekktaeylaelldkvieevgaen...... 93 
                 P+++++ g+lL e ++e   ++k+i    + ++++i++D+++++++++++ +++++p+++      d+++e+ +a+++ e l + +e++ a+       
  EEA19925.1 123 PDRHRIGGSLLTELYTES--YTKTIGIWRQIQHLNITVDETSNINHQRVMVITITTPQRSWLYCLKDMENERLNAKNITEWLLHQLEALLATLfdgdid 219
                 89999*********9998..4554444445577**************************9999999***********9999999999855544444455 PP

      DUF659  94 ...Vvqvitdnasnykkagklleekyp..tifwtpcaahclnlmledilklkwvke 144
                    + +  td+ s ++ +++ l++k p  + f++pc +h+l+l+++d+l +k  + 
  EEA19925.1 220 wkcINSLSTDTCSTMRLVWEILQRKSPlqHAFMIPCDSHGLQLIFKDLLDMKVSQA 275
                 555********************8765328*******************9765443 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 1.9
      DUF659  94 Vvqvitdnasnykkagklleekyptifwtpca 125
                 + +vit   s+y+   ++ e k + i+w  ++
  EEA19925.1 317 IASVITRWGSQYNLINSVNELKESLIQWAQSV 348
                 67788888887774433333344456666555 PP

>> Dimer_Tnp_hAT  hAT family C-terminal dimerisation region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   0.1   2.3e-09   1.1e-05      11      83 ..     496     563 ..     478     565 .. 0.91

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 2.3e-09
                    ---TT....--HHHHHHHTTTTSHHHHHHHHHHHTS-S-TTTTHHHHHHTHHHHH-TTT---HHHHHHHHHHH CS
  Dimer_Tnp_hAT  11 vlrrkeksefdvlewwkensskyPnlsklardvLsipvssaasErsFstlgkvllesrnsleplnveallcie 83 
                    ++     +e +++ +w e  +  P l  +a ++    + s+++Er+Fs +   +++ rn+l  + ve+ll+++
     EEA19925.1 496 CW-----EESEITIFWLEAADIAPKLASFANRLIHTVANSVTAERAFSLMNLQHTKIRNRLSVEQVEKLLFLQ 563
                    33.....4689************************************************************97 PP

>> DUF2110  Uncharacterized protein conserved in archaea (DUF2110)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.1   2.8e-05      0.12      95     168 ..     127     200 ..     124     210 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 2.8e-05
     DUF2110  95 ripkdelkpLgegspeqiaerFGlvqhlpleveveeveeeekeiearltdeqvdrlyewkkgkedrlivnsatr 168
                 ri  + l++L++ s ++ +  +  +qhl ++v+ +++ ++++ +  ++t  q+  ly +k ++++rl++ ++t 
  EEA19925.1 127 RIGGSLLTELYTESYTKTIGIWRQIQHLNITVDETSNINHQRVMVITITTPQRSWLYCLKDMENERLNAKNITE 200
                 566778999************************9998888899999************************9996 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   6.9   0.00019      0.87      65     125 ..     554     614 ..     538     621 .. 0.92

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00019
      APG6_N  65 elleeLkelekereeleaelaaleeelealeeeeerfwreynelqlelleleeeldsleaq 125
                 e +e+L  l+ ++ +l+++l++    +++le+ee++  r y+e++le ++  + l+s++ +
  EEA19925.1 554 EQVEKLLFLQINEYQLQEKLNEEPTPEQQLEDEEAESARVYREQSLEFSSILNNLNSMDQK 614
                 56789999************************************************99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (642 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       981  (0.0547158); expected 358.6 (0.02)
Passed bias filter:                      581  (0.0324056); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.65u 0.26s 00:00:00.91 Elapsed: 00:00:00.44
# Mc/sec: 4414.76
//
Query:       EEA19926.1  [L=358]
Description: G protein complex alpha subunit GanA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   4.6e-108  361.5   0.2   5.3e-108  361.3   0.2    1.0  1  G-alpha       G-protein alpha subunit
    1.9e-12   47.0   0.2    5.3e-08   32.5   0.0    2.8  2  Arf           ADP-ribosylation factor family
    1.3e-07   31.3   0.3     0.0002   20.8   0.0    2.3  2  Gtr1_RagA     Gtr1/RagA G protein conserved region
     0.0073   16.5   0.2        2.7    8.2   0.0    3.2  3  Roc           Ras of Complex, Roc, domain of DAPkinase
  ------ inclusion threshold ------
      0.032   13.6   0.0      0.056   12.9   0.0    1.4  1  TniB          Bacterial TniB protein
       0.04   13.6   0.1      0.097   12.4   0.1    1.6  1  AAA_29        P-loop containing region of AAA domain
      0.066   13.3   0.0        8.4    6.5   0.0    2.5  2  MMR_HSR1      50S ribosome-binding GTPase
       0.11   11.8   0.1       0.28   10.5   0.0    1.6  2  FtsK_SpoIIIE  FtsK/SpoIIIE family


Domain annotation for each model (and alignments):
>> G-alpha  G-protein alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  361.3   0.2  2.4e-111  5.3e-108       2     354 .]      17     348 ..      16     348 .. 0.95

  Alignments for each domain:
  == domain 1  score: 361.3 bits;  conditional E-value: 2.4e-111
                 XXXXXXXXXXXXXXXXXXE..EEEEEEEESTTSSHHHHHHHHHHHCS----HHHHHCCHHHHHHHHHHHHHHHHHHHHHTT.......HHHC-SS-SCC CS
     G-alpha   2 rtssaidkslkaerkarkkkrevkllllGqseSGKsTilkqlkllykkgfseeelatwraviqlnivrsiktilealesleselsesfelqelkerldp 100
                 r++  idk++++++k+  +  +vk+lllG++eSGKsTi+kq+++++ +gf e+e+++ ravi++n+v ++k ++++++++++e+    e++++++    
  EEA19926.1  17 RINAGIDKQIRSDKKTYDR--TVKMLLLGAGESGKSTIIKQMRIIHSGGFPEDERRQNRAVIYSNLVVAFKVLMDIMQTQKIEF----EKESNQALGIF 109
                 67899********999999..**********************************************************99999....56666666666 PP

                 CS-HCHHHH..........HHCCHHC-HCHHHHHHHHCCSHHHHHHHCCGCCTT--TTHHHHHCTHHHHCSTT----CHHHHCS-----SEEEEEEECT CS
     G-alpha 101 lkkveasliaklssateeeqeiefnpraevgedikaLwndpgiqelyerrnkiklednaeyFlddleritspdYlptddDilkarlktvGisetkfevd 199
                 l k ea+  +        ++e +     e+ e++ +Lw+d g+q+ ++r +++ l dn++yF+++l+r+++p +lp ++D+l++rl+t+Gi+et fe++
  EEA19926.1 110 LAKTEADV-D--------TDEAFADL--EIKEAMTELWSDSGVQKAVARGHEFALHDNLHYFFNSLDRLFTPGWLPDNQDMLHSRLRTTGITETLFELG 197
                 66666664.3........25556666..*********************************************************************** PP

                 -TEEEEEEEE-SSHHHHHGTCCCTTTECEEEEEEEGGGTT-B-SS-TTSBHHHHHHHHHHCCCC-GGGTTSEEEEEEE-HHHHHHHCCCS-GGGCCTT- CS
     G-alpha 200 sklefrivdvgGqrserkkWvpffddvdaiiFlvslsefdqvlyedekvnrleeslklFkeicnnkllkntpiiLflnKlDileeKlkkgklskyfpsy 298
                  +l+fr++dvgGqrserkkW+++f++v++++F+v+ls++dq l ed++ n+++e++ lF+++ n +++k++pi+LflnK+D+++ Kl  ++++k+fp+y
  EEA19926.1 198 -QLNFRMMDVGGQRSERKKWIHCFEGVQCLLFMVALSGYDQSLLEDQNANQMHEAMMLFESLANGEWFKRKPIMLFLNKMDLFRTKLPLSPINKHFPDY 295
                 .************************************************************************************************** PP

                 -H.CCHHHHHHHHHHHHHHCCCCCCESGGSCEEEEEE-TT-HHHHHHHHHHHHHHH CS
     G-alpha 299 egrkndlesvlkylrnkFeeihkeksnnrrkiythftsatdtkevqkviesvrdti 354
                 +g++ d+++++ky+ ++F++i++    ++r+iy+h+t+atdt+ ++ +++sv+d+i
  EEA19926.1 296 SGSSTDFDTAAKYFADRFRSINR---MPDREIYIHYTNATDTTLLKATMDSVQDMI 348
                 *********************88...7888************************98 PP

>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.6   0.1   6.4e-05      0.14       7      35 ..      29      57 ..      24      62 .. 0.85
   2 !   32.5   0.0   2.4e-11   5.3e-08      43     129 ..     184     280 ..     176     348 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 6.4e-05
                GGTT.TTEEEEEEEESTTSSHHHHHHHHH CS
         Arf  7 klklkkkelrilllGLDnaGKtTilkklk 35
                  k++++ +++lllG  ++GK+Ti+k+++
  EEA19926.1 29 DKKTYDRTVKMLLLGAGESGKSTIIKQMR 57
                5567799******************9975 PP

  == domain 2  score: 32.5 bits;  conditional E-value: 2.4e-11
                 SSSSSEEEEEEEETTEEEEEEEE-SSGGGGGGGGGGCTTESEEEEEEETT..-CT........THHHHHHHHHHHCTSGCCTTSEEEEEEE-TTSTT CS
         Arf  43 vPTigfnveeleiknlkftvwDvGGqeklRplWknYfektdavifvvDsa..dre........RleeakeeLkalleeeelkevallvlaNKqDlpe 129
                   T+g +    e  +l+f++ DvGGq++ R+ W + fe ++ ++f+v  +  d++         ++ea   +++l + e  k+ +++++ NK+Dl  
  EEA19926.1 184 LRTTGITETLFELGQLNFRMMDVGGQRSERKKWIHCFEGVQCLLFMVALSgyDQSlledqnanQMHEAMMLFESLANGEWFKRKPIMLFLNKMDLFR 280
                 56888888888999********************************964322332111122226777777778888888899************965 PP

>> Gtr1_RagA  Gtr1/RagA G protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.5   0.0   0.00052       1.2       1      33 [.      38      73 ..      38     111 .. 0.80
   2 !   20.8   0.0   8.7e-08    0.0002      42     179 ..     194     351 ..     177     357 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00052
   Gtr1_RagA  1 kvLLmGksgsGKtsmrs...iiFdnylardtlrlga 33
                k+LL+G ++sGK+++ +   ii++   ++d +r + 
  EEA19926.1 38 KMLLLGAGESGKSTIIKqmrIIHSGGFPEDERRQNR 73
                89************9754448888888888877555 PP

  == domain 2  score: 20.8 bits;  conditional E-value: 8.7e-08
   Gtr1_RagA  42 vrflgnltlnlwDcgGqeafveeylssqkeeifrnvgvliyVfDve.......sreleedletlkeilealrq..yspeakvfvlihKmDliqederee 131
                 +  lg+l++ ++D+gGq++  ++       + f+ v+ l++++  +       +++  +++++   ++e l +    ++  +  +++KmDl + +   +
  EEA19926.1 194 F-ELGQLNFRMMDVGGQRSERKKW-----IHCFEGVQCLLFMVALSgydqsllEDQNANQMHEAMMLFESLANgeWFKRKPIMLFLNKMDLFRTKLPLS 286
                 3.5899***********9987775.....799***********99988877764456666777777777776511568899****************** PP

   Gtr1_RagA 132 ifeerkeeireeiekleke.................eiqffaTSiwdeslykAfssivqklipnl 179
                  ++++  +++  ++++++                  ei ++ T   d +l kA    vq++i + 
  EEA19926.1 287 PINKHFPDYSGSSTDFDTAakyfadrfrsinrmpdrEIYIHYTNATDTTLLKATMDSVQDMIIQK 351
                 **********99998887788999999999999*99*******************9999999654 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.2   0.0    0.0012       2.7       1      19 [.      38      56 ..      38      80 .. 0.92
   2 ?    0.4   0.1      0.31     7e+02      20      69 ..      94     144 ..      87     163 .. 0.67
   3 ?    3.7   0.0      0.03        67      52     119 ..     195     277 ..     164     278 .. 0.60

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0012
                EEEEESSTTSSHHHHHHCH CS
         Roc  1 KvvlvGdsgvGKtsllkrf 19
                K++l+G +++GK++++k++
  EEA19926.1 38 KMLLLGAGESGKSTIIKQM 56
                89**************985 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.31
                 CT-CCC-EEETTTTEEEEEEECG.GSGGCTTBTTTTCEEEEEEEE-SGGCT CS
         Roc  20 vedkfsekekstigvdfltkevt.kikgvendkkvkkvklniWDtaGqerf 69 
                 ++ +f++++++ +g+ ++++e+  ++++   d ++k+   ++W  +G ++ 
  EEA19926.1  94 QKIEFEKESNQALGIFLAKTEADvDTDEAFADLEIKEAMTELWSDSGVQKA 144
                 556799999999999888776531334445677788888899966665444 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.03
                 TTTCEEEEEEEE-SGGCTTT.T-HHHHCTSCEEEEE....EE.....GHHHHCHHHHHHHHHHHCS.....SS-EEEEEE-TT CS
         Roc  52 kvkkvklniWDtaGqerfrs.lhplylreaalailv....yd.....srssenlkeWlkelkkvag.....kspvilvgnkiD 119
                 ++ ++++++ D++Gq   r+   +++   + l+++v    yd     +++ ++++e +  +++ a+     ++p++l  nk+D
  EEA19926.1 195 ELGQLNFRMMDVGGQRSERKkWIHCFEGVQCLLFMValsgYDqslleDQNANQMHEAMMLFESLANgewfkRKPIMLFLNKMD 277
                 4567899999****988876356666665555555533334444432222334444444444333211222678888888888 PP

>> TniB  Bacterial TniB protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   2.5e-05     0.056      31      75 ..      32      78 ..      13      93 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.5e-05
        TniB 31 krkrmpnlllvGdsnnGKtmivekFarlhppe..kdedaekvpvlvv 75
                + +r+ ++ll+G  + GK++i+++ +  h+    +de+++++ v++ 
  EEA19926.1 32 TYDRTVKMLLLGAGESGKSTIIKQMRIIHSGGfpEDERRQNRAVIYS 78
                467999********************999877324566778888886 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   4.3e-05     0.097      24      39 ..      38      53 ..      26      63 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 4.3e-05
      AAA_29 24 atlltGpsGsGKSTll 39
                 +ll G+ +sGKST++
  EEA19926.1 38 KMLLLGAGESGKSTII 53
                58*************9 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0     0.017        38       2      19 ..      39      56 ..      38     112 .. 0.89
   2 ?    6.5   0.0    0.0037       8.4      33     114 .]     186     275 ..     175     275 .. 0.66

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.017
                EEEEESTTSSHHHHHHHH CS
    MMR_HSR1  2 vaivGrpNvGKStLinal 19
                ++++G   +GKSt+i+++
  EEA19926.1 39 MLLLGAGESGKSTIIKQM 56
                5789999********987 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0037
                 SSSEEEEEEEETTEEEEEEECGGCSSHHHHHHHHHHHHHHHHC.TSEEEEEEETT......TTCSHHHHHHHHHHHHH.............TTSEEEEE CS
    MMR_HSR1  33 TrdinegrvklkgkeielvDtpGliegaseekglgkaflalee.adlillvvdas......eeklkpldeeleellee.............akkplilv 111
                 T+ i+e  ++l++ +++++D+ G        ++++k++    e ++ +l++v +s            +d++ +++ e              ++kp++l 
  EEA19926.1 186 TTGITETLFELGQLNFRMMDVGG-Q------RSERKKWIHCFEgVQCLLFMVALSgydqslL-----EDQNANQMHEAmmlfeslangewfKRKPIMLF 272
                 667777777888899********.3......3455555554454789999998775543221.....34444444333555566777788888888888 PP

                 EES CS
    MMR_HSR1 112 lnk 114
                 lnk
  EEA19926.1 273 LNK 275
                 887 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00013      0.28      27      59 ..      22      56 ..       7      59 .. 0.76
   2 ?   -2.9   0.0       1.5   3.4e+03       2      38 ..     239     276 ..     238     277 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00013
                  TS-EEEEEGGGS-...SEEEE--TTSSHHHHHHHH CS
  FtsK_SpoIIIE 27 sgnplvldlkkma..shllvaGatgsGKStalntL 59
                  +++ + +d k+      +l++Ga +sGKSt ++ +
    EEA19926.1 22 IDKQIRSDKKTYDrtVKMLLLGAGESGKSTIIKQM 56
                  666666777666666779************99876 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.5
                   HHHHHTSHHHHT---TTEEEEEEET.TS-EEEEEGGGS CS
  FtsK_SpoIIIE   2 Llevleskkfrtessqlpvalgkei.sgnplvldlkkm 38 
                   Lle+++ ++++++ + ++ +   e+  ++p++l+l+km
    EEA19926.1 239 LLEDQNANQMHEAMMLFESLANGEWfKRKPIMLFLNKM 276
                   78888899999999999999999998999999998887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (358 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       514  (0.0286686); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.51u 0.24s 00:00:00.75 Elapsed: 00:00:00.41
# Mc/sec: 2624.32
//
Query:       EEA19927.1  [L=368]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-10   40.4  19.5      2e-10   40.4  19.5    1.8  2  DUF1713   Mitochondrial domain of unknown function (DUF1713)
  ------ inclusion threshold ------
        4.4    8.3   4.8          2    9.3   0.7    2.4  3  TT_ORF2   TT viral ORF2


Domain annotation for each model (and alignments):
>> DUF1713  Mitochondrial domain of unknown function (DUF1713)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.5       1.4   1.3e+04      20      26 ..       6      12 ..       6      12 .. 0.80
   2 !   40.4  19.5   2.2e-14     2e-10       2      33 .]     336     367 ..     335     367 .. 0.97

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 1.4
     DUF1713 20 lrKrtRf 26
                lr+++R+
  EEA19927.1  6 LRRAMRT 12
                7999995 PP

  == domain 2  score: 40.4 bits;  conditional E-value: 2.2e-14
     DUF1713   2 dSVlrKRrkKMkKHKyKKlrKrtRflrrklgk 33 
                 +SV+r+R++KMkKHK+KKl+++tR+lrrkl+k
  EEA19927.1 336 ISVRRQRKLKMKKHKFKKLLRKTRTLRRKLDK 367
                 69****************************98 PP

>> TT_ORF2  TT viral ORF2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.7   0.00023         2      34      97 ..      52     110 ..      48     122 .. 0.73
   2 ?   -1.7   0.0       0.6   5.4e+03      52      73 ..     250     271 ..     223     280 .. 0.58
   3 ?   -1.8   0.1      0.63   5.7e+03      54      76 ..     333     355 ..     321     364 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00023
     TT_ORF2  34 kHlidlatqlsleepqgkrpkrklilrqspalpaakeekkklakwlettgedaetgpseegdgt 97 
                 +H  + ++  s ++++++ + r++++  s++ pa++ +  k+++ +   g+ a++g +  gd t
  EEA19927.1  52 QHQRRYSSSSSKPPVPPNDGSRPIDASSSQQAPANPSAGRKVKESQ---GRKAGAGAA--GDVT 110
                 56677788889999******************99998886655554...555555332..4443 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.6
     TT_ORF2  52 rpkrklilrqspalpaakeekk 73 
                 +p+ + +++++  l+aa+++ +
  EEA19927.1 250 PPAAPEPYNPEDVLEAAEAATG 271
                 3333335555555555555443 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 0.63
     TT_ORF2  54 krklilrqspalpaakeekkkla 76 
                   ++++r++++l+++k + kkl+
  EEA19927.1 333 MYTISVRRQRKLKMKKHKFKKLL 355
                 55788999999999998887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (368 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       993  (0.0553851); expected 358.6 (0.02)
Passed bias filter:                      434  (0.0242066); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.24s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 2660.41
//
Query:       EEA19928.1  [L=159]
Description: vacuolar ATP synthase 16 kDa proteolipid subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.9e-35  120.4  34.6    1.2e-21   76.8  15.5    2.1  2  ATP-synt_C   ATP synthase subunit C


Domain annotation for each model (and alignments):
>> ATP-synt_C  ATP synthase subunit C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.9  11.1   1.6e-17   2.9e-13       1      60 []      16      75 ..      16      75 .. 0.97
   2 !   76.8  15.5   6.7e-26   1.2e-21       1      60 []      92     151 ..      92     151 .. 0.99

  Alignments for each domain:
  == domain 1  score: 49.9 bits;  conditional E-value: 1.6e-17
                HHHHHHH.GGGHHHHHHHHHHHHHHHHHHHHSGHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ATP-synt_C  1 lgaglavGlsalgsGigiGkagsagiravarnpklftksliilafaeaialygLivalil 60
                lg+  a++++++g+++g++kag + +++ +++p+l+++ ++++++a++ia+ygL+v++++
  EEA19928.1 16 LGCTSAIVFTCFGAAYGTAKAGVGVCGMAVLRPDLIVRNIVPIVMAGIIAIYGLVVSVLI 75
                6788899**************************************************997 PP

  == domain 2  score: 76.8 bits;  conditional E-value: 6.7e-26
                 HHHHHHH.GGGHHHHHHHHHHHHHHHHHHHHSGHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ATP-synt_C   1 lgaglavGlsalgsGigiGkagsagiravarnpklftksliilafaeaialygLivalil 60 
                 lgaglavGl++l++G++iG++g+ag+r++a++p+l++++++il+fae+++lygLival++
  EEA19928.1  92 LGAGLAVGLAGLAAGFAIGIVGDAGVRGSAQQPRLYVGMILILIFAEVLGLYGLIVALLM 151
                 7*********************************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (159 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       700  (0.0390429); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.23s 00:00:00.62 Elapsed: 00:00:00.37
# Mc/sec: 1285.84
//
Query:       EEA19929.1  [L=117]
Description: vacuolar ATP synthase 16 kDa proteolipid subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.3e-28   99.1  26.1    5.8e-22   77.8  15.5    2.1  2  ATP-synt_C   ATP synthase subunit C
  ------ inclusion threshold ------
        0.4   10.4   4.1       0.52   10.0   4.1    1.1  1  Tetraspanin  Tetraspanin family
        8.6    6.4   6.8        3.3    7.7   0.3    2.4  3  SH           Viral small hydrophobic protein


Domain annotation for each model (and alignments):
>> ATP-synt_C  ATP synthase subunit C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.5   2.9     5e-10     3e-06      30      60 .]       3      33 ..       1      33 [. 0.94
   2 !   77.8  15.5   9.7e-26   5.8e-22       1      60 []      50     109 ..      50     109 .. 0.99

  Alignments for each domain:
  == domain 1  score: 27.5 bits;  conditional E-value: 5e-10
                HHSGHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ATP-synt_C 30 arnpklftksliilafaeaialygLivalil 60
                +++p+l+++ ++++++a++ia+ygL+v++++
  EEA19929.1  3 VLRPDLIVRNIVPIVMAGIIAIYGLVVSVLI 33
                689**************************97 PP

  == domain 2  score: 77.8 bits;  conditional E-value: 9.7e-26
                 HHHHHHH.GGGHHHHHHHHHHHHHHHHHHHHSGHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ATP-synt_C   1 lgaglavGlsalgsGigiGkagsagiravarnpklftksliilafaeaialygLivalil 60 
                 lgaglavGl++l++G++iG++g+ag+r++a++p+l++++++il+fae+++lygLival++
  EEA19929.1  50 LGAGLAVGLAGLAAGFAIGIVGDAGVRGSAQQPRLYVGMILILIFAEVLGLYGLIVALLM 109
                 7*********************************************************97 PP

>> Tetraspanin  Tetraspanin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   4.1   8.7e-05      0.52       5     105 ..       8     112 ..       7     116 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 8.7e-05
                  XXXXXXXXXXXXXXXXXXXXXXXX..XXX.....................X..XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
                  xxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Tetraspanin   5 lfffnllfwligivllavGvwlrl..khaeaalacllsesaedpailaill..ivvGvllfllgflGcigalkenkcllltfsllllvlfllelaagi 98 
                  l++ n++ ++++ ++ ++G+ + +   ++++++  l++   +  a la++l  +++G+++ ++g +G+ g+ ++ +   ++ ++l++  +l + ++++
   EEA19929.1   8 LIVRNIVPIVMAGIIAIYGLVVSVliANDLNQRLPLYTGFIQLGAGLAVGLagLAAGFAIGIVGDAGVRGSAQQPRLYVGMILILIFAEVLGLYGLIV 105
                  56789999999999999995555557778788888888888888888877722455669999999999999999999999999999888888888888 PP

                  XXX--HH CS
                  xxxxxxx RF
  Tetraspanin  99 lgfvfsd 105
                   ++++s 
   EEA19929.1 106 ALLMNSR 112
                  6555544 PP

>> SH  Viral small hydrophobic protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.3     0.028   1.7e+02       3      32 ..       3      32 ..       1      36 [. 0.80
   2 ?   -2.8   0.1       1.1   6.5e+03       7      14 ..      42      49 ..      39      50 .. 0.77
   3 ?    7.7   0.3   0.00056       3.3       3      30 ..      79     106 ..      78     111 .. 0.90

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.028
          SH  3 aiqPPlyPtflllillsliitlyvwiisti 32
                 ++P l    ++ i+++ ii++y  ++s +
  EEA19929.1  3 VLRPDLIVRNIVPIVMAGIIAIYGLVVSVL 32
                56777777788889999******9999975 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1.1
          SH  7 PlyPtfll 14
                Ply  f+ 
  EEA19929.1 42 PLYTGFIQ 49
                99999975 PP

  == domain 3  score: 7.7 bits;  conditional E-value: 0.00056
          SH   3 aiqPPlyPtflllillsliitlyvwiis 30 
                 a qP ly  ++l+++++ ++ ly  i++
  EEA19929.1  79 AQQPRLYVGMILILIFAEVLGLYGLIVA 106
                 77*********************99986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (117 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       666  (0.0371465); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.37u 0.26s 00:00:00.63 Elapsed: 00:00:00.39
# Mc/sec: 890.00
//
Query:       EEA19930.1  [L=198]
Description: hypothetical protein PMAA_006960 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (198 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       411  (0.0229238); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.26s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1482.70
//
Query:       EEA19931.1  [L=510]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (510 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       430  (0.0239835); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.59u 0.26s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 3251.71
//
Query:       EEA19932.1  [L=57]
Description: stress response RCI peptide, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.7e-25   86.5   8.6    1.1e-24   86.4   8.6    1.0  1  Pmp3      Proteolipid membrane potential modulator


Domain annotation for each model (and alignments):
>> Pmp3  Proteolipid membrane potential modulator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.4   8.6   6.1e-29   1.1e-24       1      48 [.       7      54 ..       7      55 .. 0.98

  Alignments for each domain:
  == domain 1  score: 86.4 bits;  conditional E-value: 6.1e-29
        Pmp3  1 dillillaiilPPlaValksGcsadllinilLtllgylPgviHAfyii 48
                di++i+ aiilPP++V+l++Gc+adllini+Lt+lgy+Pg+iHA+yii
  EEA19932.1  7 DICKIIFAIILPPVGVFLERGCGADLLINICLTILGYIPGIIHALYII 54
                89*********************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (57 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       272  (0.015171); expected 358.6 (0.02)
Passed bias filter:                      174  (0.00970495); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.26s 00:00:00.64 Elapsed: 00:00:00.43
# Mc/sec: 400.31
//
Query:       EEA19933.1  [L=793]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00029   20.9   7.3     0.0006   19.9   7.3    1.5  1  CFEM      CFEM domain
  ------ inclusion threshold ------
        2.9    7.4   3.3        5.1    6.6   3.3    1.3  1  Stevor    Subtelomeric Variable Open Reading frame


Domain annotation for each model (and alignments):
>> CFEM  CFEM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   7.3   6.7e-08    0.0006       3      65 ..      49     119 ..      47     120 .. 0.75

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 6.7e-08
                 TTS-GGGTCGGG---TT..SS..S-TT-HHHHH.H-HHHHHHHH....HHHHHH--THHHHHHHHHHHHHH CS
        CFEM   3 salPkCaqdClaeavkk..ss.gCakddtaCiC.tnaklqseit....dCvtaaCtaeealaavnaasslC 65 
                 +++P Ca +C++e +++   +  C ++d++C+C tn++   +i     +C+ ++C+ + +++  ++  ++C
  EEA19933.1  49 DSIPPCALPCVQEFIRTqyAAgICCSTDLDCLCrTNTTSGLTIGevslACIVGSCPSDIVSTEGSVGYAIC 119
                 689**********997756556799********8666654444322247******9987777666666666 PP

>> Stevor  Subtelomeric Variable Open Reading frame
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   3.3   0.00056       5.1     157     261 ..     161     267 ..     144     271 .. 0.59

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.00056
      Stevor 157 svgsvlltliglaaakaaavaa.kvalsaealkklasslsilnlfsesslesalkaavsaaaasdlagtaasaassafepygiaalvllilavvliiLY 254
                 s +s+ lt++++  + +  + + ++ ++a+a+++++  ++ l  f ++   s +  a+sa +as++a++ +s++s a+   +ia  + +i  v++ iL+
  EEA19933.1 161 SGASTALTTVAVSSTPSGSTLVtTARITATATAATTLPITALTTFPSTVTLSGI-PATSAPTASSAAAKSTSLSSPAVIGVSIASGISVIFLVAVAILF 258
                 334555666666555555444422233333333333334444444333333333.55666777777888889999999999999998888888888888 PP

      Stevor 255 i..wlyrRR 261
                     l+rRR
  EEA19933.1 259 CgrKLRRRR 267
                 733466666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (793 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       810  (0.0451782); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.70u 0.31s 00:00:01.01 Elapsed: 00:00:00.48
# Mc/sec: 4987.66
//
Query:       EEA19934.1  [L=461]
Description: phosphatidyl synthase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.9e-23   80.7   0.0    1.5e-22   79.6   0.0    1.6  1  Hydrolase_6     Haloacid dehalogenase-like hydrolase
    1.4e-12   47.4   0.0    1.9e-11   43.9   0.0    2.8  2  Hydrolase_like  HAD-hyrolase-like
  ------ inclusion threshold ------
      0.088   13.1   0.0          6    7.1   0.0    2.8  3  Hydrolase       haloacid dehalogenase-like hydrolase
      0.088   12.7   0.0       0.32   10.9   0.0    1.8  2  Lipase_3        Lipase (class 3)


Domain annotation for each model (and alignments):
>> Hydrolase_6  Haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.6   0.0   3.3e-26   1.5e-22       1     101 []      99     204 ..      99     204 .. 0.96

  Alignments for each domain:
  == domain 1  score: 79.6 bits;  conditional E-value: 3.3e-26
                  EEEESTTTSEETTEE-TTHHHHHHHHHHTT.....-EEEEEE---SS-HHHHHHHH.HHTT----GGGEEEHHHHHHHHHHHHSXXXEEEEESX..HH CS
  Hydrolase_6   1 flfDidGvLwrgdkaipgaaealnalraag.....kpvvllTNnsskseeeyakkl.eklgvditeeqvvtsataaaeylkkrkadkkvlvige..eg 90 
                  f+fDidGvL+rg+++ip+a+ea+++l+ ++     +p++++TN+++k+eee++ +l ++l++++++ q+++ +t+++e+ +k    ++vlv+g+  e+
   EEA19934.1  99 FAFDIDGVLIRGGRVIPEAVEAMKVLNGENefgikVPYIFVTNGGGKTEEERCLDLsRQLELEVSPGQFICGHTPMREMAEK---YNTVLVVGGvgEK 193
                  78******************************************************999**********************9...8999999985568 PP

                  HHHHHHHTTXE CS
  Hydrolase_6  91 lreelkeagfk 101
                  +re+++ +gfk
   EEA19934.1 194 CREVAEGYGFK 204
                  *********97 PP

>> Hydrolase_like  HAD-hyrolase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0      0.64   2.9e+03      43      57 ..     181     195 ..     178     208 .. 0.76
   2 !   43.9   0.0   4.2e-15   1.9e-11       2      75 .]     330     420 ..     329     420 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.64
                     -EEEEESSSSS-TTT CS
  Hydrolase_like  43 wksvLVltGvtrped 57 
                     +++vLV  Gv ++ +
      EEA19934.1 181 YNTVLVVGGVGEKCR 195
                     6899**999988755 PP

  == domain 2  score: 43.9 bits;  conditional E-value: 4.2e-15
                     .STTSSHHHHHHHHHH..........---GGGEEEEES-TTTHHHHHHHCT-EE.........EEESSSSS-TTTHHHHHHHHT---SEEES- CS
  Hydrolase_like   2 lgKPepemydfalevl..........gsdpeevlmiGDrlatDiagAnnaGwks.........vLVltGvtrpedleepehkptyvaddlaea 75 
                     +gKP+ ++++fa + l          + +p+ v+++GD++++Di+g n++ ++          +LV+tGv++++  +   + p+ +a+++ +a
      EEA19934.1 330 FGKPQLGTFEFATRLLrqwrrdthgiNRAPDTVYFVGDTPESDIRGTNEYNAHAasgdaewfsILVKTGVFQEGTIP--RYPPNKIANNVLDA 420
                     69**************9999999988888*******************999665555555555**********9977..678********986 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.0    0.0013         6       3      26 ..      98     121 ..      97     163 .. 0.84
   2 ?   -1.4   0.0      0.53   2.4e+03     133     176 ..     179     221 ..     174     229 .. 0.71
   3 ?    2.4   0.0     0.037   1.6e+02     163     204 ..     320     374 ..     294     380 .. 0.69

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0013
                 EEEEESBTTTBCHHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase   3 tvvfDkdGTLttgepsvedvivsa 26 
                 +++fD+dG+L++g +++ ++++  
  EEA19934.1  98 AFAFDIDGVLIRGGRVIPEAVEAM 121
                 689**********98887777766 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.53
                 TTEEEEEEESSEHHHHHHHHHHTTGGGE.SEEEEHHCES.STTTSH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxx.xxxxxx RF
   Hydrolase 133 agievvlltgdnpetaeraanqlGddyf.daviasdiet.vakpsp 176
                  ++++vl+ g+  e  +++a+ +G   f d+v  +di +  a+  p
  EEA19934.1 179 EKYNTVLVVGGVGEKCREVAEGYG---FkDVVTPGDIIKtNAETTP 221
                 467899999999999999999999...6566655555544555555 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.037
                 EEEHHCES..STTTSHHHHHHHHHHHT..........STGGGEEEEESSHH.HHH CS
                 xxxxxxxx..xxxxxxxxxxxxxxxxx..........xxxxxxxxxxxxxx.xxx RF
   Hydrolase 163 viasdiet..vakpspegkvaaireLq..........gkpeevamVGDgvn.Daa 204
                 v +++ +t  ++kp    ++ a r L+            p  v +VGD++  D+ 
  EEA19934.1 320 VTGKELTTiaFGKPQLGTFEFATRLLRqwrrdthginRAPDTVYFVGDTPEsDIR 374
                 444444446688887777777777775566777775556999*******999986 PP

>> Lipase_3  Lipase (class 3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   7.1e-05      0.32      74     134 ..     306     362 ..     305     365 .. 0.85
   2 ?   -1.8   0.0      0.56   2.5e+03      31      58 ..     409     437 ..     373     447 .. 0.56

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 7.1e-05
                 HHHHHHHHHHHHHHHTT-SS---EEEEEES----B-HHHHHHHHT-TTEEEEEEEETT--G CS
    Lipase_3  74 LGgalAlLaaldlvengenekkkvtvvtfGqPrvgnkefaklvdsqlnkkvlrvvntnDiv 134
                 +G+  A+L al+ + +g    k++t ++fG+P+ g  efa+++ +q +   + +    D v
  EEA19934.1 306 MGALRASLEALYKAVTG----KELTTIAFGKPQLGTFEFATRLLRQWRRDTHGINRAPDTV 362
                 57778999999999999....89*******************9999888777777777765 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.56
                 TT-EEEHHHHHHHHS-HHHHHHHHHHH.H CS
    Lipase_3  31 eggkvhsgfleayeeslreqvlkelkr.l 58 
                    k+ +  l+a+++ ++ ++ k +k+ +
  EEA19934.1 409 PPNKIANNVLDAVKFGMQREFAKAVKEhV 437
                 45567777777777777777777777644 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (461 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       425  (0.0237046); expected 358.6 (0.02)
Passed bias filter:                      386  (0.0215294); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.56u 0.24s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3225.73
//
Query:       EEA19935.1  [L=393]
Description: hypothetical protein PMAA_007010 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      0.001   19.3   0.0     0.0018   18.5   0.0    1.4  1  BTB       BTB/POZ domain


Domain annotation for each model (and alignments):
>> BTB  BTB/POZ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.0     1e-07    0.0018      29     103 ..     119     201 ..     110     209 .. 0.81

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 1e-07
                 HHHHH-HHHHHHHTST......TTTTCCCEEEEETTSGHHHHHHHHHHHHHSEEEC-...CGGGHHHHHHHHHHHT-HHHHHHH CS
         BTB  29 vLaarSpyFkalftsk......eieessvseielddvepeafealLefiYtgeleit...seenleelLaaadllqiprlkkac 103
                  L  +Sp+Fk+++t+       + ++ + +ei  +  + eaf +lL++i+++  +++   + ++l+++  + d++q+++ ++  
  EEA19935.1 119 HLTVASPVFKSILTGPwkesatYLQKGT-VEILAEGWDIEAFLILLRVIHCQFNQVPrklTLDMLAKVAVIVDYYQCKEAVRFF 201
                 58899***********887775544444.47999******************99999877778888888888999999987765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (393 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       441  (0.024597); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 2612.58
//
Query:       EEA19936.1  [L=480]
Description: lipase/serine esterase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.6e-50  170.2   0.0    6.7e-50  169.6   0.0    1.2  1  DUF676         Putative serine esterase (DUF676)
    9.3e-06   25.6   0.0    1.6e-05   24.9   0.0    1.4  1  Palm_thioest   Palmitoyl protein thioesterase
    1.9e-05   25.4   0.0    2.6e-05   25.0   0.0    1.3  1  Abhydrolase_6  Alpha/beta hydrolase family
     0.0023   17.7   0.0     0.0057   16.4   0.0    1.6  1  PGAP1          PGAP1-like protein
     0.0025   17.7   0.0     0.0045   16.9   0.0    1.4  1  Lipase_3       Lipase (class 3)
     0.0097   15.4   0.0      0.016   14.8   0.0    1.3  1  Lipase_2       Lipase (class 2)
  ------ inclusion threshold ------
       0.18   11.4   0.2          4    7.0   0.1    2.3  2  Abhydrolase_1  alpha/beta hydrolase fold


Domain annotation for each model (and alignments):
>> DUF676  Putative serine esterase (DUF676)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  169.6   0.0   2.6e-53   6.7e-50       3     215 ..      38     238 ..      36     243 .. 0.92

  Alignments for each domain:
  == domain 1  score: 169.6 bits;  conditional E-value: 2.6e-53
      DUF676   3 kkdhLvVlvHGlqgnsaDlelikeqlekikeklpeekieflmsennesktfkgidvlgerlaeevlevvkkkkdk...nkkiSfvghSlGgliaraaia 98 
                 k+dhL+VlvHGl+gn+++l +++ ++++  ++ ++++ ++++++n+ + t++gi++ ger+++e+ +++++ + k   ++k+S+vg+SlGgl+ar+ai+
  EEA19936.1  38 KPDHLCVLVHGLWGNPSHLDYVASAIRE--RHGKDKVYILAAQRNSGTYTYDGIELGGERVVHEIEDTLDQLSAKghsITKLSVVGYSLGGLVARYAIG 134
                 689*************************..5456667777777788899**************************9*999******************* PP

      DUF676  99 klkekemtlkeaikglepvtfitlasPhLGvlysskslinlglalleklkkslsmeqlgltGrdLflkddkdeknsllykllkdekdlkliealklFkr 197
                 +l++     ++++++lepv+f+t+ sPh+Gv+   k        + ++++++l +++++ +Gr+Lf++dd + + + l+ +l+d +   +i+ l++Fk+
  EEA19936.1 135 LLEA-----NGTLDKLEPVNFTTFVSPHVGVRSPIKG-------WPSHMWNVLGARTISISGRQLFMIDDFRGTGKPLLSVLADPN-SIFIKGLAKFKN 220
                 9983.....46899***********************.......99999999*******************************997.667788****** PP

      DUF676 198 rvlyanvvndrivplase 215
                 r +yan+vndr+ +++++
  EEA19936.1 221 RSVYANIVNDRSTVFYTT 238
                 ****************94 PP

>> Palm_thioest  Palmitoyl protein thioesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.9   0.0   6.3e-09   1.6e-05       3     109 ..      44     175 ..      43     244 .. 0.71

  Alignments for each domain:
  == domain 1  score: 24.9 bits;  conditional E-value: 6.3e-09
  Palm_thioest   3 viwhGldsaesnmqklaeliekli.gtyvknveigesea.......edrkasffgnlndqveavckklelangfhaiGfSQGglflRaliercddkk 91 
                   v++hGl  + s ++ +a++i++++ + +v++++ ++++        e   + ++++++d +++  +k +  ++  ++G+S Ggl++R  i   + + 
    EEA19936.1  44 VLVHGLWGNPSHLDYVASAIRERHgKDKVYILAAQRNSGtytydgiELGGERVVHEIEDTLDQLSAKGHSITKLSVVGYSLGGLVARYAIGLLEANG 140
                   889***4444449***********54888888855444467777778889999999999999988884456899*****************998777 PP

  Palm_thioest  92 n.....vrnlislggpqaGvfg............l 109
                   +       n+ ++ +p+ Gv              l
    EEA19936.1 141 TldklePVNFTTFVSPHVGVRSpikgwpshmwnvL 175
                   689988669***********985554444444330 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.0   0.0     1e-08   2.6e-05       2     104 ..      44     162 ..      43     294 .. 0.60

  Alignments for each domain:
  == domain 1  score: 25.0 bits;  conditional E-value: 1e-08
                    EEE--GC.....G.C.HHHHHHHHCCT.CEEEEE--TTSTS-GGCS--HHH........CHHHHHHHCCTT.....TTSEEEEEETCHHHHHHHHH CS
  Abhydrolase_6   2 lllHGagssassW.l.vapLaallaag.vhvlapDlpGhGrsdpppldled........ladlaalldelaa...gggpvvlvGHSlGGalalaaa 83 
                    +l+HG+++++s+  + ++ ++++ +++ v +la ++ + G +    ++++         +++++++ld l a   +  +  +vG+SlGG++a  a 
     EEA19936.1  44 VLVHGLWGNPSHLdYvASAIRERHGKDkVYILAAQR-NSG-T----YTYDGielggervVHEIEDTLDQLSAkghSITKLSVVGYSLGGLVARYAI 133
                    9****9999888854444554433333754465555.889.7....8887744444443466677777777666667777**********888855 PP

                    HCC.............EEEEES-..----TTT CS
  Abhydrolase_6  84 pla...........lvvgvlldppptalpagl 104
                     l+           ++++ +++p +   + + 
     EEA19936.1 134 GLLeangtldklepVNFTTFVSPHV---GVRS 162
                    5557778888887777778888832...2222 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0   2.2e-06    0.0057      46     111 ..      72     135 ..      41     160 .. 0.73

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 2.2e-06
       PGAP1  46 ldfftvdfneelsaldGrtlldqaeylndaIkyIlslysssekeptsviliGHSmGGivaraaltl 111
                 +  +++  n      dG  l    e + + I+  l++ s++ + +t++ ++G S+GG+var a+ l
  EEA19936.1  72 VYILAAQRNSGTYTYDGIELG--GERVVHEIEDTLDQLSAKGHSITKLSVVGYSLGGLVARYAIGL 135
                 555555555555566666665..4556677888899999**********************99866 PP

>> Lipase_3  Lipase (class 3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.0   1.8e-06    0.0045      45     108 ..      94     159 ..      25     167 .. 0.85

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 1.8e-06
                 S-HHHHHHHHHHHHHHHTT-.EEEEEEEETHHHHHHHHHHHHHHHTT-SS.---EEEEEES----B CS
    Lipase_3  45 eslreqvlkelkrllekype.ysivvtGHSLGgalAlLaaldlvengene.kkkvtvvtfGqPrvg 108
                 e +  +++++l++l +k  + +++ v+G SLGg +A  a   l +ng  +  ++v+  tf +P vg
  EEA19936.1  94 ERVVHEIEDTLDQLSAKGHSiTKLSVVGYSLGGLVARYAIGLLEANGTLDkLEPVNFTTFVSPHVG 159
                 6788899999***999988769***************99999999998777899**********99 PP

>> Lipase_2  Lipase (class 2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   6.1e-06     0.016      76     131 ..     116     172 ..     107     264 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 6.1e-06
    Lipase_2  76 kvdivahsmGvpiaRkailGgkcvdtnedLg.epltskvdtfvsvaganaGlllcas 131
                 k ++v++s+G+ +aR+ai   ++  t ++L  +++t  v   v+v+++ +G+     
  EEA19936.1 116 KLSVVGYSLGGLVARYAIGLLEANGTLDKLEpVNFTTFVSPHVGVRSPIKGWPSHMW 172
                 789***************999999999999625899************999987665 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.0     0.055   1.4e+02      55      79 ..      51      76 ..      13      77 .. 0.83
   2 ?    7.0   0.1    0.0016         4      68      90 ..     110     132 ..      96     136 .. 0.79

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.055
                   SHHHHHHHHH.HHHHHCTTSSEEEEE CS
  Abhydrolase_1 55 gtasvaddld.rildalgddkltlvG 79
                   g+ s+ d++  +i++++g dk+++++
     EEA19936.1 51 GNPSHLDYVAsAIRERHGKDKVYILA 76
                   5667899999999**********985 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0016
                    HHCTTSSEEEEEETHHHHHHHHH CS
  Abhydrolase_1  68 dalgddkltlvGhSmGGmialay 90 
                      + + kl +vG+S+GG++a+++
     EEA19936.1 110 KGHSITKLSVVGYSLGGLVARYA 132
                    5578899************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (480 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       797  (0.0444531); expected 358.6 (0.02)
Passed bias filter:                      692  (0.0385967); expected 358.6 (0.02)
Passed Vit filter:                        74  (0.00412739); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.62u 0.31s 00:00:00.93 Elapsed: 00:00:00.47
# Mc/sec: 3068.89
//
Query:       EEA19937.1  [L=592]
Description: RNA exonuclease Rex3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        2.7    7.9   5.9       0.47   10.3   1.3    2.0  2  BTK       BTK motif


Domain annotation for each model (and alignments):
>> BTK  BTK motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.2       0.1   1.8e+03       1       5 [.     326     330 ..     326     331 .. 0.89
   2 ?   10.3   1.3   2.6e-05      0.47      14      29 ..     354     369 ..     348     370 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.1
         BTK   1 kYHPg 5  
                 +YHPg
  EEA19937.1 326 TYHPG 330
                 7***8 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 2.6e-05
         BTK  14 CCkqtdktapGCtpvt 29 
                 CC++t  t +GCt+ +
  EEA19937.1 354 CCNETVGTSAGCTKAE 369
                 *************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (592 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       549  (0.0306208); expected 358.6 (0.02)
Passed bias filter:                      413  (0.0230353); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.43
# Mc/sec: 4109.67
//
Query:       EEA19938.1  [L=124]
Description: 60S ribosomal protein L22, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.5e-47  160.5   0.2    1.8e-47  160.2   0.2    1.0  1  Ribosomal_L22e  Ribosomal L22e protein family


Domain annotation for each model (and alignments):
>> Ribosomal_L22e  Ribosomal L22e protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  160.2   0.2     1e-51   1.8e-47       1     109 []      13     121 ..      13     121 .. 0.98

  Alignments for each domain:
  == domain 1  score: 160.2 bits;  conditional E-value: 1e-51
  Ribosomal_L22e   1 kkklkftidcskpvedkildvaefekfLkerikvngktgnlgdkveieregkskvtvtsevkfskrylkyltkkyLkkkqlrdwlrvvasskesY 95 
                     k++ kf+i++s+p++dki+dv++fekfL++rikv+g++gnlgd+v+i+++g+ k++v+++++fs+rylkyltkk+Lkk+qlrdwlrvv++sk  Y
      EEA19938.1  13 KVTSKFIINASQPASDKIFDVSAFEKFLHDRIKVEGRVGNLGDNVQISQSGDGKIEVVAHIPFSGRYLKYLTKKFLKKQQLRDWLRVVSTSKGVY 107
                     5789******************************************************************************************* PP

  Ribosomal_L22e  96 eLryfnieedeeee 109
                     eLr++n+ +de++e
      EEA19938.1 108 ELRFYNVVSDEADE 121
                     **********9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (124 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       593  (0.0330749); expected 358.6 (0.02)
Passed bias filter:                      465  (0.0259356); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.29s 00:00:00.75 Elapsed: 00:00:00.47
# Mc/sec: 788.28
//
Query:       EEA19939.1  [L=1043]
Description: Pfs, NACHT and Ankyrin domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.6e-43  147.2   9.0    9.7e-17   61.3   2.0    4.9  6  Ank_2         Ankyrin repeats (3 copies)
    3.4e-36  123.2   7.6    2.5e-10   40.7   0.5    6.4  6  Ank_4         Ankyrin repeats (many copies)
    4.1e-26   90.7   2.1    1.9e-08   34.4   0.0    4.1  5  Ank_5         Ankyrin repeats (many copies)
    1.4e-24   83.5   3.6     0.0006   20.1   0.1    7.8  7  Ank_3         Ankyrin repeat
    1.6e-20   72.6   4.7     0.0017   18.7   0.0    6.4  5  Ank           Ankyrin repeat
    4.7e-09   35.9   0.0      9e-09   34.9   0.0    1.5  1  PNP_UDP_1     Phosphorylase superfamily
    0.00016   22.1   0.0    0.00073   20.0   0.0    2.1  1  AAA_16        AAA ATPase domain
      0.002   18.1   0.0     0.0054   16.7   0.0    1.7  1  NACHT         NACHT domain
     0.0022   18.2   0.0     0.0089   16.3   0.0    2.1  1  AAA_22        AAA domain
  ------ inclusion threshold ------
       0.13   11.4   0.0        1.6    7.9   0.0    2.3  2  NB-ARC        NB-ARC domain
       0.16   11.8   0.0       0.37   10.6   0.0    1.5  1  AAA_29        P-loop containing region of AAA domain
       0.23   11.9   0.3       0.86   10.0   0.0    2.0  2  RNA_helicase  RNA helicase
        0.3   10.3   1.6        8.6    5.5   0.4    2.3  2  KAP_NTPase    KAP family P-loop domain


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       5.9   8.1e+03      11      48 ..     355     363 ..     349     408 .. 0.60
   2 !    8.9   0.0    0.0016       2.2      28      75 ..     808     863 ..     779     872 .. 0.66
   3 !   33.0   0.0   4.9e-11   6.8e-08       3      77 ..     812     912 ..     809     918 .. 0.71
   4 !   45.5   0.0   6.1e-15   8.4e-12      10      83 .]     871     951 ..     863     951 .. 0.82
   5 !   61.3   2.0     7e-20   9.7e-17       1      83 []     925    1017 ..     925    1017 .. 0.88
   6 !   33.8   0.1   2.7e-11   3.7e-08      27      74 ..     988    1041 ..     985    1043 .] 0.83

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 5.9
       Ank_2  11 elvklLlegadpnkngktaLhyAakngnleivklLleh 48 
                 +++++Ll                             +h
  EEA19939.1 355 KTCQWLL-----------------------------NH 363
                 2333333.............................32 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.0016
       Ank_2  28 taLhyAakngnleivklLle.h........adndgrtpLhyAarsghleivklLlek 75 
                 + L++ a +g+ ++v++ l+ h         +++   pL++A  sg+ e+v  Ll+ 
  EEA19939.1 808 SLLYILADKGYPNLVRTWLKdHsqwqipihRERYR-YPLFAALASGNNETVAALLNT 863
                 66788888888888866665345655553222433.488888888888888888832 PP

  == domain 3  score: 33.0 bits;  conditional E-value: 4.9e-11
       Ank_2   3 lAakngnlelvklLl.egadpn...k..ngktaLhyAakngnleivklLleh.................ad...ndgrtpLhyAarsghleivklLlek 75 
                 + a +g+++lv+  l  ++      +    + +L++A  +gn+e+v +Ll+                   d   +++rtpL +Aa++g+l+iv lLle 
  EEA19939.1 812 ILADKGYPNLVRTWLkDHSQWQipiHreRYRYPLFAALASGNNETVAALLNTassmmngtditeglknrKDlkeYKNRTPLSWAAQEGRLDIVTLLLET 910
                 5556677778888883222222333145779*******************94455666666656654441155688*********************98 PP

       Ank_2  76 ga 77 
                 g 
  EEA19939.1 911 GL 912
                 75 PP

  == domain 4  score: 45.5 bits;  conditional E-value: 6.1e-15
       Ank_2  10 lelvklLlegadpnk.ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinlkd 83 
                 +++ + L + +d+++ +++t+L +Aa++g l+iv lLle        d  grt L  Aa++gh+ ++klL+ekga+in+ d
  EEA19939.1 871 TDITEGLKNRKDLKEyKNRTPLSWAAQEGRLDIVTLLLETglvideSDGGGRTGLSRAAENGHEAVAKLLIEKGANINISD 951
                 445555655566663589*********************77885555577****************************987 PP

  == domain 5  score: 61.3 bits;  conditional E-value: 7e-20
       Ank_2    1 LhlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinlkd 83  
                  L  Aa+ng+  + klL+ +ga++n  +    taLh+A +n ++ +++lL+e+      +d++  t+LhyA  +g++ +++lL+ekgad+n+ d
  EEA19939.1  925 LSRAAENGHEAVAKLLIeKGANINisDgSRSTALHHALQNRHEAMARLLIEKgadiniIDESRSTALHYALGNGYEAVARLLIEKGADVNMSD 1017
                  678*****888999999*99***98537889***********999******8866555558899***********9999***********987 PP

  == domain 6  score: 33.8 bits;  conditional E-value: 2.7e-11
       Ank_2   27 ktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLle 74  
                   taLhyA  ng++ +++lL+e+       d++  t+Lh+A+++g++ +v+lL e
  EEA19939.1  988 STALHYALGNGYEAVARLLIEKgadvnmSDESRSTALHHASQNGYEAVVRLLSE 1041
                  69*********97888****98866444447788***********999999975 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0       2.7   3.7e+03      11      23 ..     351     363 ..     345     368 .. 0.82
   2 ?    5.2   0.0     0.024        34       4      23 ..     844     863 ..     841     873 .. 0.88
   3 !   35.2   0.0   9.3e-12   1.3e-08       1      55 []     888     941 ..     888     941 .. 0.98
   4 !   35.2   0.4   9.8e-12   1.3e-08       5      55 .]     925     974 ..     925     974 .. 0.96
   5 !   40.7   0.5   1.8e-13   2.5e-10       2      55 .]     955    1007 ..     954    1007 .. 0.97
   6 !   40.2   0.0   2.6e-13   3.6e-10       2      54 ..     988    1039 ..     987    1039 .. 0.97

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 2.7
       Ank_4  11 sgrlelvrlLlek 23 
                 ++  +++++Ll++
  EEA19939.1 351 DNYKKTCQWLLNH 363
                 788999*****98 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.024
       Ank_4   4 aLhyaaisgrlelvrlLlek 23 
                 +L++a +sg+ e+v+ Ll++
  EEA19939.1 844 PLFAALASGNNETVAALLNT 863
                 79****************86 PP

  == domain 3  score: 35.2 bits;  conditional E-value: 9.3e-12
       Ank_4   1 eltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++t+L +aa++grl++v lLle+g  i+++ ++ G+t l +Aa +g+  ++klL+
  EEA19939.1 888 NRTPLSWAAQEGRLDIVTLLLETGLVIDES-DGGGRTGLSRAAENGHEAVAKLLI 941
                 689**************************9.***********************8 PP

  == domain 4  score: 35.2 bits;  conditional E-value: 9.8e-12
       Ank_4   5 LhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 L +aa+ g++ +++lL+ekga+in + ++s  talh+A+++ +  +++lL+
  EEA19939.1 925 LSRAAENGHEAVAKLLIEKGANINIS-DGSRSTALHHALQNRHEAMARLLI 974
                 56899********************9.**9********************8 PP

  == domain 5  score: 40.7 bits;  conditional E-value: 1.8e-13
       Ank_4    2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  +taLh+a +  ++ ++rlL+ekgadin   ++s  talh+A+ +g+  +++lL+
  EEA19939.1  955 STALHHALQNRHEAMARLLIEKGADINII-DESRSTALHYALGNGYEAVARLLI 1007
                  79**************************8.**9*******************98 PP

  == domain 6  score: 40.2 bits;  conditional E-value: 2.6e-13
       Ank_4    2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54  
                  +taLhya   g + ++rlL+ekgad+n++ ++s  talh+A ++g+  +++lL
  EEA19939.1  988 STALHYALGNGYEAVARLLIEKGADVNMS-DESRSTALHHASQNGYEAVVRLL 1039
                  79**************************9.99999***************998 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.2   0.0   6.3e-05     0.086      14      51 ..     886     923 ..     877     928 .. 0.84
   2 !   22.9   0.0   5.5e-08   7.6e-05       1      56 []     907     961 ..     907     961 .. 0.93
   3 !   34.4   0.0   1.4e-11   1.9e-08       1      56 []     940     994 ..     940     994 .. 0.98
   4 !   34.4   0.0   1.4e-11   1.9e-08       1      56 []     973    1027 ..     973    1027 .. 0.97
   5 !   16.4   0.0   6.3e-06    0.0087       1      35 [.    1006    1039 ..    1006    1042 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 6.3e-05
       Ank_5  14 gggntpLhvAakygaadvvrlLlargadlnltdsrGlt 51 
                  +  tpL +Aa  g++d+v lLl+ g+ ++  d+ G+t
  EEA19939.1 886 YKNRTPLSWAAQEGRLDIVTLLLETGLVIDESDGGGRT 923
                 3344********************99999999999987 PP

  == domain 2  score: 22.9 bits;  conditional E-value: 5.5e-08
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 Lle g   ++ +dggg t L  Aa++g+  v++lL++ ga++n+ d++ +tal++A
  EEA19939.1 907 LLETG-LVIDESDGGGRTGLSRAAENGHEAVAKLLIEKGANINISDGSRSTALHHA 961
                 67777.7777799****************************************998 PP

  == domain 3  score: 34.4 bits;  conditional E-value: 1.4e-11
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 L+e+g a++n +dg + t+Lh+A  +++  ++rlL++ gad+n+ d++ +tal++A
  EEA19939.1 940 LIEKG-ANINISDGSRSTALHHALQNRHEAMARLLIEKGADINIIDESRSTALHYA 994
                 89999.*************************************************9 PP

  == domain 4  score: 34.4 bits;  conditional E-value: 1.4e-11
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56  
                  L+e+g ad+n  d+ + t+Lh+A  +g+  v+rlL++ gad n+ d++ +tal++A
  EEA19939.1  973 LIEKG-ADINIIDESRSTALHYALGNGYEAVARLLIEKGADVNMSDESRSTALHHA 1027
                  89999.***********************************************998 PP

  == domain 5  score: 16.4 bits;  conditional E-value: 6.3e-06
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlL 35  
                  L+e+g advn +d+ + t+Lh+A+ +g+  vvrlL
  EEA19939.1 1006 LIEKG-ADVNMSDESRSTALHHASQNGYEAVVRLL 1039
                  89999.********************999999987 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0       1.8   2.5e+03      13      27 ..     351     366 ..     348     368 .. 0.75
   2 ?    3.7   0.0      0.09   1.2e+02       2      23 ..     841     862 ..     840     865 .. 0.90
   3 !   10.9   0.0   0.00043      0.59       2      23 ..     888     909 ..     887     915 .. 0.91
   4 !   17.3   0.0   3.6e-06     0.005       2      31 .]     921     949 ..     920     949 .. 0.96
   5 !   20.1   0.1   4.4e-07    0.0006       4      31 .]     956     982 ..     954     982 .. 0.96
   6 !   17.9   0.0   2.2e-06    0.0031       4      31 .]     989    1015 ..     987    1015 .. 0.95
   7 ?    5.5   0.0     0.025        34       4      23 ..    1022    1041 ..    1020    1043 .] 0.91

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 1.8
       Ank_3  13 gnle.ivkfLlenkga 27 
                 +n++  +++Ll+++g 
  EEA19939.1 351 DNYKkTCQWLLNHPGY 366
                 5664469*****9885 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.09
       Ank_3   2 GetpLhlAarsgnleivkfLle 23 
                 +++pL+ A+ sgn e v +Ll+
  EEA19939.1 841 YRYPLFAALASGNNETVAALLN 862
                 689***********99999997 PP

  == domain 3  score: 10.9 bits;  conditional E-value: 0.00043
       Ank_3   2 GetpLhlAarsgnleivkfLle 23 
                 ++tpL +Aa  g+l+iv +Lle
  EEA19939.1 888 NRTPLSWAAQEGRLDIVTLLLE 909
                 79*******************9 PP

  == domain 4  score: 17.3 bits;  conditional E-value: 3.6e-06
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvna 31 
                 G+t L +Aa++g+ +++k+L+e kga++n+
  EEA19939.1 921 GRTGLSRAAENGHEAVAKLLIE-KGANINI 949
                 899*******************.9****97 PP

  == domain 5  score: 20.1 bits;  conditional E-value: 4.4e-07
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadvna 31 
                 t+Lh+A+ + + +++++L+e kgad+n+
  EEA19939.1 956 TALHHALQNRHEAMARLLIE-KGADINI 982
                 9*******************.9*****7 PP

  == domain 6  score: 17.9 bits;  conditional E-value: 2.2e-06
       Ank_3    4 tpLhlAarsgnleivkfLlenkgadvna 31  
                  t+Lh+A+ +g  +++++L+e kgadvn+
  EEA19939.1  989 TALHYALGNGYEAVARLLIE-KGADVNM 1015
                  9*******************.9****95 PP

  == domain 7  score: 5.5 bits;  conditional E-value: 0.025
       Ank_3    4 tpLhlAarsgnleivkfLle 23  
                  t+Lh+A  +g  ++v++L e
  EEA19939.1 1022 TALHHASQNGYEAVVRLLSE 1041
                  9************9999976 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.0   0.00094       1.3       3      24 ..     889     911 ..     888     915 .. 0.90
   2 !   15.8   0.0     1e-05     0.014       2      31 ..     921     951 ..     920     951 .. 0.91
   3 !   16.2   0.2   7.6e-06      0.01       4      31 ..     956     984 ..     955     985 .. 0.94
   4 !   18.7   0.0   1.2e-06    0.0017       4      31 ..     989    1017 ..     988    1018 .. 0.90
   5 !    7.8   0.0    0.0036       4.9       4      21 ..    1022    1039 ..    1021    1042 .. 0.92

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00094
                 BBHHHHHHHHTTHHHHHHHH.TT CS
         Ank   3 nTPLHlAatngkkriiklLL.hG 24 
                 +TPL +Aa++g ++i+ lLL  G
  EEA19939.1 889 RTPLSWAAQEGRLDIVTLLLeTG 911
                 6********9*********9666 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 1e-05
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlnald 31 
                 G+T L +Aa ng++ ++klL+ +GAn+n+ d
  EEA19939.1 921 GRTGLSRAAENGHEAVAKLLIeKGANINISD 951
                 7788999**************99*****976 PP

  == domain 3  score: 16.2 bits;  conditional E-value: 7.6e-06
                 BHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnlnald 31 
                 T+LH A +n ++ +++lL+ +GA++n+ d
  EEA19939.1 956 TALHHALQNRHEAMARLLIeKGADINIID 984
                 9******99999*******99*****987 PP

  == domain 4  score: 18.7 bits;  conditional E-value: 1.2e-06
                  BHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    4 TPLHlAatngkkriiklLL.hGAnlnald 31  
                  T+LH+A  ng + +++lL+ +GA++n+ d
  EEA19939.1  989 TALHYALGNGYEAVARLLIeKGADVNMSD 1017
                  9****99888899******99*****877 PP

  == domain 5  score: 7.8 bits;  conditional E-value: 0.0036
                  BHHHHHHHHTTHHHHHHH CS
         Ank    4 TPLHlAatngkkriiklL 21  
                  T+LH A++ng + +++lL
  EEA19939.1 1022 TALHHASQNGYEAVVRLL 1039
                  9**************976 PP

>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.9   0.0   6.5e-12     9e-09      18     231 ..      68     301 ..      51     306 .. 0.71

  Alignments for each domain:
  == domain 1  score: 34.9 bits;  conditional E-value: 6.5e-12
                 H...EEEEEEEEEE.TTEEEEEEEETTEEEEEEE--...SSHHHHHHHHHHHHHHHC--SEE..EEEEEEEES..STTT-TT-EEEEEEEEESSSCCGC CS
   PNP_UDP_1  18 s...pleetpfgregrgfkfvtGtlkgkpvvivstG...iGkpnaavvaeirllkefgvkai..iriGtaGgl..npdlkvGDvvipddainfdgrspl 106
                       e++p  ++  +  +v+G++k++++vi +      G +naa + ++ l   f +k +  +++G+ Gg+  + d+++GDvv+ ++++++d++   
  EEA19939.1  68 MlddVHESLPRNPD-DTNSYVLGSIKRRNIVISCLPagqYGIVNAA-TVATNLKRTF-PKILmtLMVGIGGGVpsKGDIRLGDVVVGTRIMQYDLGKIV 163
                 33335666777777.99***************99999999******.8888888899.66663379*******99999**************8888876 PP

                 CTHHCCTCCCCTTSSEE--HHHHHHHHHCHHTTT...............................TTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEE CS
   PNP_UDP_1 107 ygpkeegqyfpdsydapadpelrallkeaaealg...............................ikvhrGvvatadgfyaeteaelrllrrlgadave 174
                    k e   +p ++ +     l+ ++ ++++a++                               ik+h+G++a+++++      +++  r+l + + e
  EEA19939.1 164 ADGKFERTAVPKVQSP-----LLGTALNHLRAKHelnasripsilqqkleryielypgvcdppgtIKIHYGAIASGNQVMKHGITRDNVARELDIICFE 257
                 6644442333333333.....33333332222222333334477777777888888899999*********************999999********** PP

                 SSHHHHHHHHHHTT--EEEEEEEEETTTBETTCTCH.HCCCHHHHHHHHHHHHHHHH CS
   PNP_UDP_1 175 MEtaavaqlArelgipfaairvvsdlaaggadaeatheeveefaqeaaknaaallla 231
                 ME+a    +     ip++ +r++ d+ +           +ee ++ aa +aaa +++
  EEA19939.1 258 MEAAGTMDI-----IPCLPVRGICDYSDS--------HKNEEWQRYAAATAAAYARE 301
                 **9877665.....999999999993333........33444444444444444444 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   0.0   5.3e-07   0.00073      25     154 ..     380     503 ..     370     520 .. 0.62

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 5.3e-07
      AAA_16  25 elvllsGesGvGKsslvrellralekd.......ggiflrgkcdqlesaipysalaqalareellrqlldeaesaeleawrekleeala.....avpel 111
                 + + +sG +G GKs++++ ++  ++++         +f++++  +le+       ++   r +ll qll+e        +r+ l+++l      ++++ 
  EEA19939.1 380 GFLWISGKPGAGKSTIMKFAYSNMKRAcradvktASFFFNARGGSLER------STSGMYR-SLLLQLLEE--------YRD-LQTVLDnpdilPQNQE 462
                 5789*************9999988877666665423333333333322......3333323.333333333........222.2333331222233333 PP

      AAA_16 112 agaeasrllellkrllallsrderplvlvlDdlqwadeaslql 154
                 ++   + l +l++++++ l + +r +  ++D l+  de++ + 
  EEA19939.1 463 DCPPLNILKDLFRDAISVLGQ-RR-FTCFVDALDECDEQQVMD 503
                 4444499*********88887.66.************977665 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   3.9e-06    0.0054       3      96 ..     382     499 ..     381     528 .. 0.69

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 3.9e-06
                 EEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-.......-HCHHHCCCCTS--SSS-C...............CHHHHCCSCCC CS
       NACHT   3 vilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgna....rsladllfsqlpepaapvse...............vwavllelper 82 
                 +++ G++G GK+t ++   + +++ +   ++   +Ff++ r  s +  +    rsl  +l +++ +++   ++               + + l + + +
  EEA19939.1 382 LWISGKPGAGKSTIMKFAYSNMKRACRADVK-TASFFFNARGGSLERSTsgmyRSLLLQLLEEYRDLQTVLDNpdilpqnqedcpplnILKDLFRDAIS 479
                 79*************9999999999988876.9999999998777777733445555555555555544444466666666666666633333333333 PP

                 EE......EEEE-STT-SS- CS
       NACHT  83 lL......lilDglDelvtd 96 
                 +L        +D+lDe+ ++
  EEA19939.1 480 VLgqrrftCFVDALDECDEQ 499
                 33666655667999999875 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   6.5e-06    0.0089       4     125 ..     378     522 ..     373     530 .. 0.76

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 6.5e-06
      AAA_22   4 tagilvvtGesGtGKTtllrrlleqldeeakaeeerpevv..fvtlpsst...sskdllrellralglelka...................erlsseel 78 
                 ++g+l + G +G+GK+t ++   ++ +++    +++++++  f+++ +++   s + ++r ll +l +e  +                   + + +++l
  EEA19939.1 378 HHGFLWISGKPGAGKSTIMKFAYSNMKRA-C--RADVKTAsfFFNARGGSlerSTSGMYRSLLLQLLEEYRDlqtvldnpdilpqnqedcpPLNILKDL 473
                 899*****************988887432.2..245555566888888888899999999999999988888999999999999999999878888888 PP

      AAA_22  79 l.ealeqalraravielliiDEaqhlrs.eealeeLrsllnl.srkgvql 125
                 + +a+    ++r++  +  +DE +   + ++++e++ +l +  +++++q+
  EEA19939.1 474 FrDAISVLGQRRFTCFVDALDECDEQ-QvMDMVEFFEDLGEQaKDHNIQF 522
                 87777777777777222357777775.56777777777766565777766 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   0.0    0.0011       1.6      22      45 ..     381     404 ..     368     409 .. 0.86
   2 ?    0.4   0.0      0.21   2.9e+02      39      70 ..     772     802 ..     769     810 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0011
                 EEEEEESTTSSHHHHHHHHCCSHC CS
      NB-ARC  22 vvalvGmgGvGKttlakqilnksd 45 
                 ++ ++G++G GK+t++k ++++++
  EEA19939.1 381 FLWISGKPGAGKSTIMKFAYSNMK 404
                 7899*************9998855 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.21
                 HHCCSHCCCCCCBTEEEEEEEESXXHHHHHHH CS
      NB-ARC  39 qilnksdevegrFdsvawvvvsktdkseeile 70 
                 +++ + +e  ++F++v w+ + +++++++i e
  EEA19939.1 772 EVVVQ-NEFLSEFPIVSWIKMNNHFEKHTIRE 802
                 55556.678899***************99976 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00027      0.37      20      39 ..     377     396 ..     370     399 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00027
      AAA_29  20 dlkgatlltGpsGsGKSTll 39 
                 + +g+  ++G+ G+GKST++
  EEA19939.1 377 QHHGFLWISGKPGAGKSTIM 396
                 5568899***********97 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00062      0.86       1      22 [.     382     403 ..     382     424 .. 0.79
   2 ?   -1.6   0.1       2.6   3.6e+03      42      82 ..     491     533 ..     486     540 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00062
  RNA_helicase   1 iwlyGpsgeGKStlakeLakal 22 
                   +w++G++g GKSt++k   +++
    EEA19939.1 382 LWISGKPGAGKSTIMKFAYSNM 403
                   6**************9755544 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 2.6
  RNA_helicase  42 dfwdgYtgqevvvidDfgqvkdee.nps.dlaelirlvsstpy 82 
                   d +d +++q+v+ + +f ++  e+ +++ + + ++     +py
    EEA19939.1 491 DALDECDEQQVMDMVEFFEDLGEQaKDHnIQFRICFSSRHYPY 533
                   6678899999999999999986665555366666666556665 PP

>> KAP_NTPase  KAP family P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0     0.028        38      24      48 ..     383     407 ..     360     465 .. 0.72
   2 ?    5.5   0.4    0.0062       8.6     172     200 ..     483     511 ..     467     525 .. 0.78

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.028
  KAP_NTPase  24 gLygkWGsGKssllnkledelkefa 48 
                  ++gk G+GKs++ ++  +++k   
  EEA19939.1 383 WISGKPGAGKSTIMKFAYSNMKRAC 407
                 689999***************9884 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.0062
  KAP_NTPase 172 qkrlVvviDdLDrceteevlqlleavkll 200
                 q+r   ++D+LD c+ ++v+ + e  + l
  EEA19939.1 483 QRRFTCFVDALDECDEQQVMDMVEFFEDL 511
                 688999**************999877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1043 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       607  (0.0338558); expected 358.6 (0.02)
Passed bias filter:                      581  (0.0324056); expected 358.6 (0.02)
Passed Vit filter:                        76  (0.00423894); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.82u 0.29s 00:00:01.10 Elapsed: 00:00:00.44
# Mc/sec: 7083.00
//
Query:       EEA19940.1  [L=156]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      6e-05   23.0   0.1    8.3e-05   22.6   0.1    1.2  1  Bys1      Blastomyces yeast-phase-specific protein


Domain annotation for each model (and alignments):
>> Bys1  Blastomyces yeast-phase-specific protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.6   0.1   4.6e-09   8.3e-05      84     144 ..      89     154 ..      66     156 .] 0.80

  Alignments for each domain:
  == domain 1  score: 22.6 bits;  conditional E-value: 4.6e-09
        Bys1  84 dnstveyslgnsggnpfeghklt...lkssddrcpriewpegiptgvs..sgscgssenliltlcp 144
                 +   + y l n  g+pfe   +t   l++++ rc  i wp+g+  g      +c  + n+ ltlc 
  EEA19940.1  89 GTNGMFYVLNNEFGDPFEYFPVTatpLNPTGPRCDPIHWPNGLNPGGHtpVRTCPLNTNFRLTLCG 154
                 4456779************999855678999***********97665412578************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (156 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       283  (0.0157845); expected 358.6 (0.02)
Passed bias filter:                      261  (0.0145574); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.24s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 1107.29
//
Query:       EEA19941.1  [L=241]
Description: hypothetical protein PMAA_007070 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    7.9e-05   22.8   0.1    0.00015   21.8   0.1    1.4  2  Dynamin_N  Dynamin family


Domain annotation for each model (and alignments):
>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   0.1   8.6e-09   0.00015     110     167 ..      48     112 ..      46     113 .. 0.88
   2 ?   -3.1   0.0       0.4   7.1e+03      25      40 ..     120     135 ..     117     174 .. 0.67

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 8.6e-09
                 -B-SSSGTTS......HHHHHHH.STTEEEEEEEETTS-CCC-CHHHHHHHHSTTBTTEEEEEE- CS
   Dynamin_N 110 Gldsvnkrdq......elvkeyi.kkadiilavtsanhdlsnsealflarevdpkgkrtivvltk 167
                 Gl+s+ ++++      elv++y+ ++++iil v++a++d+   +  + a+  d+  +rt++++ k
  EEA19941.1  48 GLISMSENEEdvkviqELVDSYLeNSRTIILTVVPASSDINIRDIIQRAHPFDKTRQRTVGIIIK 112
                 6666666665667888**********************************************966 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 0.4
                 ---SSS---S-EEEEE CS
   Dynamin_N  25 prgpnptTrrplelql 40 
                  +g++p T+r+ +l+ 
  EEA19941.1 120 NVGTEPRTARLWVLEV 135
                 5677777777776654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (241 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       572  (0.0319036); expected 358.6 (0.02)
Passed bias filter:                      509  (0.0283898); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.28s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 1712.61
//
Query:       EEA19942.1  [L=1545]
Description: WD-repeat protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      5e-81  264.5  22.1    4.1e-10   40.1   0.1   13.1 12  WD40            WD domain, G-beta repeat
    1.3e-41  140.8   0.0    5.6e-05   23.4   0.0   11.8 12  ANAPC4_WD40     Anaphase-promoting complex subunit 4 WD40 dom
      1e-14   54.2   0.0      0.024   13.6   0.0    6.7  6  Ge1_WD40        WD40 region of Ge1, enhancer of mRNA-decappin
    5.5e-14   52.3   0.1    8.5e-06   25.5   0.0    2.4  2  PQQ_2           PQQ-like domain
      4e-08   32.9   3.2      0.068   12.5   0.0    7.0  8  Nbas_N          Neuroblastoma-amplified sequence, N terminal
    4.7e-08   32.8   1.5         26    4.9   0.0    8.5  8  PD40            WD40-like Beta Propeller Repeat
    1.2e-06   28.4   0.0      0.014   15.0   0.0    4.8  5  SGL             SMP-30/Gluconolactonase/LRE-like region
    1.2e-06   28.6   0.0    2.6e-06   27.4   0.0    1.5  1  NACHT           NACHT domain
    2.5e-06   26.9   0.1    1.2e-05   24.7   0.1    1.9  1  PNP_UDP_1       Phosphorylase superfamily
    2.9e-06   27.8   0.0      2e-05   25.1   0.0    2.2  2  AAA_16          AAA ATPase domain
      5e-05   22.9   6.9        6.4    6.5   0.0    6.8  7  Proteasome_A_N  Proteasome subunit A N-terminal signature
    0.00048   18.6   0.0       0.69    8.2   0.0    3.8  4  Frtz            WD repeat-containing and planar cell polarity
     0.0011   18.4   0.0        8.3    5.6   0.0    4.3  4  WD40_like       WD40-like domain
     0.0013   17.3   0.0       0.62    8.5   0.0    3.2  3  Cytochrom_D1    Cytochrome D1 heme domain
     0.0078   16.1   0.1      0.018   15.0   0.1    1.5  1  APS_kinase      Adenylylsulphate kinase
  ------ inclusion threshold ------
       0.16   11.7   0.0       0.39   10.4   0.0    1.6  1  AAA_30          AAA domain
       0.17   12.0   0.2       0.36   10.9   0.2    1.5  1  K1              K1 glycoprotein
       0.18   11.0   0.0       0.31   10.2   0.0    1.3  1  KAP_NTPase      KAP family P-loop domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.1   0.1   4.1e-13   4.1e-10       4      38 .]     911     946 ..     908     946 .. 0.93
   2 !   38.3   0.0   1.5e-12   1.5e-09       3      38 .]     952     988 ..     950     988 .. 0.91
   3 !   30.7   0.0   3.8e-10   3.8e-07       6      38 .]    1016    1051 ..    1012    1051 .. 0.88
   4 !   30.1   0.1     6e-10     6e-07      12      38 .]    1070    1096 ..    1060    1096 .. 0.90
   5 !   10.2   0.2    0.0012       1.2      12      38 .]    1114    1140 ..    1103    1140 .. 0.83
   6 !   10.3   0.1    0.0011       1.1       6      38 .]    1151    1178 ..    1146    1178 .. 0.87
   7 !   16.9   0.0   8.8e-06    0.0088      13      38 .]    1195    1219 ..    1184    1219 .. 0.90
   8 !   34.0   0.0   3.4e-11   3.4e-08       6      37 ..    1228    1260 ..    1223    1261 .. 0.90
   9 !   14.8   0.0   4.1e-05     0.041      17      38 .]    1285    1306 ..    1265    1306 .. 0.81
  10 !   20.0   0.0   9.4e-07   0.00093       5      38 .]    1314    1354 ..    1310    1354 .. 0.83
  11 !    9.4   0.0     0.002         2       5      38 .]    1362    1395 ..    1358    1395 .. 0.84
  12 !   12.5   0.0   0.00022      0.21      13      38 .]    1411    1435 ..    1398    1435 .. 0.82

  Alignments for each domain:
  == domain 1  score: 40.1 bits;  conditional E-value: 4.1e-13
                 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 l+tl+GH +sv s+afsp+g+++as+s+Dgt+++Wd
  EEA19942.1 911 LQTLEGHsGSVVSVAFSPNGRLIASSSYDGTIKLWD 946
                 789****77799***********************9 PP

  == domain 2  score: 38.3 bits;  conditional E-value: 1.5e-12
                 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 + +tl+ H   v s+afsp+g++l+sGs+Dgt+++Wd
  EEA19942.1 952 LKHTLESHkERVESIAFSPNGRLLVSGSYDGTIKLWD 988
                 6799****555*************************9 PP

  == domain 3  score: 30.7 bits;  conditional E-value: 3.8e-10
                  EEESS.SS..EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    6 tltGH.ss..vtslafspdgawlasGsdDgtvriWd 38  
                  t+  H ++  ++s+afspdg +lasG  Dg+v++Wd
  EEA19942.1 1016 TFVHHtGPppISSVAFSPDGELLASGANDGSVKFWD 1051
                  6767755588****************99*******9 PP

  == domain 4  score: 30.1 bits;  conditional E-value: 6e-10
                  SEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   12 svtslafspdgawlasGsdDgtvriWd 38  
                   v s++fspdg++la+Gs Dgt+++Wd
  EEA19942.1 1070 RVDSVCFSPDGRLLAAGSSDGTIKLWD 1096
                  5889*************99*******9 PP

  == domain 5  score: 10.2 bits;  conditional E-value: 0.0012
                  SEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   12 svtslafspdgawlasGsdDgtvriWd 38  
                   v  +afspd ++las++ Dg+  +Wd
  EEA19942.1 1114 AVFRMAFSPDARLLASCHIDGSNGLWD 1140
                  38999****************988887 PP

  == domain 6  score: 10.3 bits;  conditional E-value: 0.0011
                  EEESSSSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    6 tltGHssvtslafspdgawlasGsdDgtvriWd 38  
                   l+GH    s++f pdg +la G  D ++ +Wd
  EEA19942.1 1151 GLSGH----SVCFAPDGGLLAIGY-DISIELWD 1178
                  57788....8899***********.*******9 PP

  == domain 7  score: 16.9 bits;  conditional E-value: 8.8e-06
                  EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   13 vtslafspdgawlasGsdDgtvriWd 38  
                  v s+afspd+++las++  +++++Wd
  EEA19942.1 1195 VLSVAFSPDSRLLASAD-GNSIKLWD 1219
                  789**********9777.*******9 PP

  == domain 8  score: 34.0 bits;  conditional E-value: 3.4e-11
                  EEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS
        WD40    6 tltGHss.vtslafspdgawlasGsdDgtvriW 37  
                  +l +H + v+s+afspdg++las+s+D+t+++W
  EEA19942.1 1228 ILNAHADmVYSVAFSPDGQLLASCSRDRTIKLW 1260
                  6789*668************************* PP

  == domain 9  score: 14.8 bits;  conditional E-value: 4.1e-05
                  EEETTSSEEEEE.ETTSEEEEEE CS
        WD40   17 afspdgawlasG.sdDgtvriWd 38  
                   fs+d+++lasG s  gtvr+Wd
  EEA19942.1 1285 IFSHDNRLLASGvS-EGTVRLWD 1306
                  39**********77.*******9 PP

  == domain 10  score: 20.0 bits;  conditional E-value: 9.4e-07
                  EEEESS.SS......EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    5 rtltGH.ss......vtslafspdgawlasGsdDgtvriWd 38  
                  +tl+G   +      vtslafsp+g++la+G+ ++ + iWd
  EEA19942.1 1314 HTLKGPsADlrmrssVTSLAFSPNGQMLAAGTNNHIIDIWD 1354
                  677777433777777****************9999999998 PP

  == domain 11  score: 9.4 bits;  conditional E-value: 0.002
                  EEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    5 rtltGH.ssvtslafspdgawlasGsdDgtvriWd 38  
                  ++l+ H   v s+ fsp++++la Gs    + +Wd
  EEA19942.1 1362 HSLELHvRAVGSITFSPNSQLLAIGS-RYEINLWD 1395
                  67777866689999************.99999998 PP

  == domain 12  score: 12.5 bits;  conditional E-value: 0.00022
                  EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   13 vtslafspdgawlasGsdDgtvriWd 38  
                    s+af pd+++l+sGs   ++++Wd
  EEA19942.1 1411 LQSIAFLPDSKLLVSGS-TAHIKFWD 1435
                  6799*************.*******9 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0   2.3e-06    0.0023      35      81 ..     915     961 ..     892     962 .. 0.89
   2 !   19.1   0.0   1.2e-06    0.0012      35      73 ..     957     995 ..     954    1004 .. 0.89
   3 !   13.4   0.0   7.2e-05     0.072      40      79 ..    1025    1064 ..    1016    1067 .. 0.86
   4 !   20.4   0.0   4.7e-07   0.00047      28      76 ..    1059    1106 ..    1056    1115 .. 0.85
   5 ?    4.5   0.0     0.044        43      30      70 ..    1107    1144 ..    1103    1156 .. 0.84
   6 ?    0.0   0.0       1.1   1.1e+03      42      58 ..    1155    1171 ..    1139    1178 .. 0.84
   7 ?    0.3   0.0      0.89   8.9e+02      41      67 ..    1195    1220 ..    1191    1226 .. 0.79
   8 !   14.3   0.0   3.7e-05     0.037      37      81 ..    1232    1276 ..    1213    1283 .. 0.85
   9 !    8.7   0.0    0.0022       2.2      45      77 ..    1285    1317 ..    1277    1325 .. 0.88
  10 !   23.4   0.0   5.6e-08   5.6e-05      38      89 ..    1326    1376 ..    1320    1379 .. 0.90
  11 ?    4.6   0.0     0.039        39      40      81 ..    1370    1410 ..    1367    1421 .. 0.85
  12 ?    0.5   0.0      0.75   7.5e+02      51      66 ..    1527    1542 ..    1523    1545 .] 0.82

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 2.3e-06
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvkse 81 
                  ++++++v s+a++p+g+l+a +  dg+++l d  +g + h+l+ ++e
   EEA19942.1 915 EGHSGSVVSVAFSPNGRLIASSSYDGTIKLWDPDTGALKHTLESHKE 961
                  567899***********************************999875 PP

  == domain 2  score: 19.1 bits;  conditional E-value: 1.2e-06
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdgevrlldaesgkvv 73 
                  ++++++v+s+a++p+g+lL+ +  dg+++l d+ +g + 
   EEA19942.1 957 ESHKERVESIAFSPNGRLLVSGSYDGTIKLWDSDTGALK 995
                  568999****************************99865 PP

  == domain 3  score: 13.4 bits;  conditional E-value: 7.2e-05
  ANAPC4_WD40   40 evrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvk 79  
                    ++s+a++pdg+lLa + +dg+v++ d  +g + + l++k
   EEA19942.1 1025 PISSVAFSPDGELLASGANDGSVKFWDPATGALERILQTK 1064
                   5899***********************9999876666555 PP

  == domain 4  score: 20.4 bits;  conditional E-value: 4.7e-07
  ANAPC4_WD40   28 rvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhsl 76  
                   r+ ++ ++ e ++v s++++pdg+lLa + sdg+++l d  +g + h++
   EEA19942.1 1059 RILQT-KSRELHRVDSVCFSPDGRLLAAGSSDGTIKLWDPVTGVLNHTM 1106
                   66666.6778889**************************9999888775 PP

  == domain 5  score: 4.5 bits;  conditional E-value: 0.044
  ANAPC4_WD40   30 wtleedkedsevrsLaWkpdgklLavaysdgevrlldaesg 70  
                   w+    ++++ v  +a++pd +lLa  + dg+  l d  +g
   EEA19942.1 1107 WDY---SNKGAVFRMAFSPDARLLASCHIDGSNGLWDPVTG 1144
                   555...788999*******************9888877666 PP

  == domain 6  score: 0.0 bits;  conditional E-value: 1.1
  ANAPC4_WD40   42 rsLaWkpdgklLavays 58  
                   +s+++ pdg lLa++y+
   EEA19942.1 1155 HSVCFAPDGGLLAIGYD 1171
                   5899**********985 PP

  == domain 7  score: 0.3 bits;  conditional E-value: 0.89
  ANAPC4_WD40   41 vrsLaWkpdgklLavaysdgevrllda 67  
                   v s+a++pd +lLa a  + +++l d 
   EEA19942.1 1195 VLSVAFSPDSRLLASADGN-SIKLWDL 1220
                   7899**********98764.5676665 PP

  == domain 8  score: 14.3 bits;  conditional E-value: 3.7e-05
  ANAPC4_WD40   37 edsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvkse 81  
                   +   v s+a++pdg+lLa    d +++l + ++g + h+l++ + 
   EEA19942.1 1232 HADMVYSVAFSPDGQLLASCSRDRTIKLWETSTGALKHTLNALEG 1276
                   566799*********************************998776 PP

  == domain 9  score: 8.7 bits;  conditional E-value: 0.0022
  ANAPC4_WD40   45 aWkpdgklLavaysdgevrlldaesgkvvhsls 77  
                    +++d++lLa ++s+g+vrl d  +g + h+l+
   EEA19942.1 1285 IFSHDNRLLASGVSEGTVRLWDPATGILKHTLK 1317
                   5899******************99998888775 PP

  == domain 10  score: 23.4 bits;  conditional E-value: 5.6e-08
  ANAPC4_WD40   38 dsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89  
                    s+v+sLa++p+g++La ++++  + + d  +g+v hsl+ +   av ++++
   EEA19942.1 1326 RSSVTSLAFSPNGQMLAAGTNNHIIDIWDLTTGTVKHSLELHVR-AVGSITF 1376
                   579************************************99988.4777776 PP

  == domain 11  score: 4.6 bits;  conditional E-value: 0.039
  ANAPC4_WD40   40 evrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvkse 81  
                    v s+ ++p+ +lLa++    e++l d+ +g++ h+++ ++ 
   EEA19942.1 1370 AVGSITFSPNSQLLAIGS-RYEINLWDMATGTLKHTVEENRA 1410
                   68899***********96.579*************9987765 PP

  == domain 12  score: 0.5 bits;  conditional E-value: 0.75
  ANAPC4_WD40   51 klLavaysdgevrlld 66  
                     La+++++g+v+++ 
   EEA19942.1 1527 GALAIGCENGRVQVIT 1542
                   579*********9986 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.1   0.0   0.00028      0.27     184     214 ..     914     945 ..     901     950 .. 0.90
   2 ?    4.0   0.0     0.021        21     185     215 ..     957     988 ..     946     993 .. 0.84
   3 !   13.6   0.0   2.4e-05     0.024     187     215 ..    1023    1051 ..     996    1059 .. 0.80
   4 !    9.1   0.0   0.00057      0.57     189     215 ..    1070    1096 ..    1057    1105 .. 0.85
   5 !    7.2   0.0    0.0021       2.1     186     215 ..    1231    1261 ..    1204    1269 .. 0.89
   6 ?   -0.4   0.0      0.43   4.3e+02     184     217 ..    1323    1356 ..    1308    1368 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00028
    Ge1_WD40 184 ieehs.liveaafspdGtalatasedGevkff 214
                 +e hs  +v+ afsp+G  +a +s dG++k++
  EEA19942.1 914 LEGHSgSVVSVAFSPNGRLIASSSYDGTIKLW 945
                 6778879***********************99 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.021
    Ge1_WD40 185 eehs.liveaafspdGtalatasedGevkffq 215
                 e+h   + + afsp+G  l   s dG++k++ 
  EEA19942.1 957 ESHKeRVESIAFSPNGRLLVSGSYDGTIKLWD 988
                 55543788899******************995 PP

  == domain 3  score: 13.6 bits;  conditional E-value: 2.4e-05
    Ge1_WD40  187 hsliveaafspdGtalatasedGevkffq 215 
                   + i++ afspdG  la  ++dG vkf+ 
  EEA19942.1 1023 PPPISSVAFSPDGELLASGANDGSVKFWD 1051
                  247999*********************95 PP

  == domain 4  score: 9.1 bits;  conditional E-value: 0.00057
    Ge1_WD40  189 liveaafspdGtalatasedGevkffq 215 
                   + +  fspdG  la+ s+dG++k++ 
  EEA19942.1 1070 RVDSVCFSPDGRLLAAGSSDGTIKLWD 1096
                  466789******************995 PP

  == domain 5  score: 7.2 bits;  conditional E-value: 0.0021
    Ge1_WD40  186 ehs.liveaafspdGtalatasedGevkffq 215 
                   h+ ++ + afspdG  la +s d ++k++ 
  EEA19942.1 1231 AHAdMVYSVAFSPDGQLLASCSRDRTIKLWE 1261
                  455478899*******************996 PP

  == domain 6  score: -0.4 bits;  conditional E-value: 0.43
    Ge1_WD40  184 ieehsliveaafspdGtalatasedGevkffqvy 217 
                  ++  s +++ afsp+G  la+ +++ ++  + + 
  EEA19942.1 1323 LRMRSSVTSLAFSPNGQMLAAGTNNHIIDIWDLT 1356
                  5667889999***********9999988888765 PP

>> PQQ_2  PQQ-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.5   0.0   8.5e-09   8.5e-06      16     201 ..     906    1098 ..     883    1175 .. 0.74
   2 !   24.3   0.1     2e-08     2e-05      15     232 ..    1216    1440 ..    1202    1441 .. 0.72

  Alignments for each domain:
  == domain 1  score: 25.5 bits;  conditional E-value: 8.5e-09
       PQQ_2   16 lWrvdlar...plgggvsravlsggtlfva.tgggrlvaldaatGkvlWettl.egpvvgaplvaegrvvvva.sdgqlialdaedGkrlWstqqrs 106 
                   W  dl++    +g+ vs a+ ++g+l++  ++ g++  +d+ tG+++ + +  +++v ++ +  +gr++v    dg++   d+++G ++++ +++ 
  EEA19942.1  906 GWGPDLQTlegHSGSVVSVAFSPNGRLIASsSYDGTIKLWDPDTGALKHTLEShKERVESIAFSPNGRLLVSGsYDGTIKLWDSDTGALKYT-VDDP 1001
                  45554433333488888889999999998878999*****************9888888888777777755554999***************.7777 PP

       PQQ_2  107 ..........eepaelrssaspava......gdtvvvgessgklvaldpkdGkvlWerelaaprgtselsrvgdisgrpvvaegtVyassgqgrlla 187 
                                        +++          v++ ++g+l a  + dG+v    +      t +l+r+ ++ +r +   ++V++s  +grlla
  EEA19942.1 1002 hgrsffeinnP--------NGATFVhhtgppPISSVAFSPDGELLASGANDGSVKFWDPA-----TGALERILQTKSRELHRVDSVCFSP-DGRLLA 1084
                  35555555431........33333334444322256666688888888888887433322.....3346677777777777777777777.666777 PP

       PQQ_2  188 ldlatgrrl.wskei 201 
                     + g  + w +++
  EEA19942.1 1085 AGSSDGTIKlW-DPV 1098
                  75555553336.334 PP

  == domain 2  score: 24.3 bits;  conditional E-value: 2e-08
       PQQ_2   15 elWrvdl.arp........lgggvsrav.lsggtlfvatgggrlvaldaatGkvlWettl.egpvvga...plvaegrvvvva.sdgqlialdaedG 96  
                  +lW +d+ a++             s a+ ++g+ l++ ++ +++  ++++tG+++ +  + eg++  +    +  ++r+++   s+g+++  d ++G
  EEA19942.1 1216 KLWDLDMgAPEpilnahadM--VYSVAFsPDGQLLASCSRDRTIKLWETSTGALKHTLNAlEGQLEWStlvIFSHDNRLLASGvSEGTVRLWDPATG 1310
                  56777773331444444332..2222440455566666******************9776588888778866777888877777777********** PP

       PQQ_2   97 krlWstqqrseepaelrssaspava...gdtvvvgessgklvaldpkdGkvlWerel.aaprgtselsrvgdisgrpvvaegtVyassgqgrllald 189 
                   ++++  +  + ++++rss ++      g+ +++g+ +  + + d+++G v  + el  +         vg+i+ +p +   +++a++  +++  +d
  EEA19942.1 1311 ILKHT-LKGPSADLRMRSSVTSLAFspnGQMLAAGTNNHIIDIWDLTTGTVKHSLELhVR--------AVGSITFSPNS---QLLAIGSRYEINLWD 1395
                  *****.77777888876665554445*************************777766333........24445555544...69999999998888* PP

       PQQ_2  190 latgr...rlwske.issinglpildgdllyvvsagelialdratGa 232 
                  +atg    +  ++       +  ++d +ll+ +s++++  +d+ tGa
  EEA19942.1 1396 MATGTlkhT-VEENrALQSIA-FLPDSKLLVSGSTAHIKFWDYTTGA 1440
                  *****6321.23332333455.7999999999999********9997 PP

>> Nbas_N  Neuroblastoma-amplified sequence, N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.17   1.7e+02     231     258 ..     920     947 ..     913     963 .. 0.81
   2 ?    0.1   0.0      0.42   4.2e+02     229     260 ..     960     991 ..     952    1012 .. 0.77
   3 ?   -1.2   0.0         1     1e+03     234     257 ..    1028    1051 ..    1017    1058 .. 0.74
   4 ?    4.3   0.0     0.021        21     224     270 ..    1063    1110 ..    1057    1114 .. 0.77
   5 !   12.5   0.0   6.8e-05     0.068     228     257 ..    1111    1140 ..    1101    1148 .. 0.89
   6 ?    2.3   0.0     0.085        85     228     259 ..    1232    1263 ..    1227    1273 .. 0.85
   7 ?    4.1   0.0     0.025        25      48      71 ..    1283    1306 ..    1275    1316 .. 0.86
   8 ?   -1.4   0.0       1.2   1.2e+03     229     259 ..    1326    1356 ..    1308    1365 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.17
      Nbas_N 231 gvfkmslspdgtllavihfsgklsiwdi 258
                  v  +++sp+g l+a   + g + +wd 
  EEA19942.1 920 SVVSVAFSPNGRLIASSSYDGTIKLWDP 947
                 5788999*******************84 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.42
      Nbas_N 229 kdgvfkmslspdgtllavihfsgklsiwdips 260
                 k+ v  +++sp+g ll    + g + +wd  +
  EEA19942.1 960 KERVESIAFSPNGRLLVSGSYDGTIKLWDSDT 991
                 566778899*******************9655 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 1
      Nbas_N  234 kmslspdgtllavihfsgklsiwd 257 
                   +++spdg lla     g++  wd
  EEA19942.1 1028 SVAFSPDGELLASGANDGSVKFWD 1051
                  456777777777777777777776 PP

  == domain 4  score: 4.3 bits;  conditional E-value: 0.021
      Nbas_N  224 rkaeekdgvfkmslspdgtllavihfsgklsiwd.ipslkqrgeweqe 270 
                   k++e   v  + +spdg lla+    g + +wd +  + +++ w+ +
  EEA19942.1 1063 TKSRELHRVDSVCFSPDGRLLAAGSSDGTIKLWDpVTGVLNHTMWDYS 1110
                  5566777777889999**999999999999999856667777777765 PP

  == domain 5  score: 12.5 bits;  conditional E-value: 6.8e-05
      Nbas_N  228 ekdgvfkmslspdgtllavihfsgklsiwd 257 
                  +k  vf+m++spd  lla  h+ g+  +wd
  EEA19942.1 1111 NKGAVFRMAFSPDARLLASCHIDGSNGLWD 1140
                  5778*************************8 PP

  == domain 6  score: 2.3 bits;  conditional E-value: 0.085
      Nbas_N  228 ekdgvfkmslspdgtllavihfsgklsiwdip 259 
                    d v+ +++spdg lla       + +w+  
  EEA19942.1 1232 HADMVYSVAFSPDGQLLASCSRDRTIKLWETS 1263
                  6799***************9999999999865 PP

  == domain 7  score: 4.1 bits;  conditional E-value: 0.025
      Nbas_N   48 rvawshdctllayaestgtvrvfd 71  
                   v +shd  lla   s gtvr++d
  EEA19942.1 1283 LVIFSHDNRLLASGVSEGTVRLWD 1306
                  4889******************99 PP

  == domain 8  score: -1.4 bits;  conditional E-value: 1.2
      Nbas_N  229 kdgvfkmslspdgtllavihfsgklsiwdip 259 
                  +  v  +++sp+g +la+      + iwd+ 
  EEA19942.1 1326 RSSVTSLAFSPNGQMLAAGTNNHIIDIWDLT 1356
                  667888999*********9999999999986 PP

>> PD40  WD40-like Beta Propeller Repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.2     0.092        92      15      28 ..     925     938 ..     918     945 .. 0.79
   2 ?    3.4   0.0     0.075        74      12      24 ..     964     976 ..     958     976 .. 0.84
   3 ?    3.4   0.0     0.077        76      10      24 ..    1025    1039 ..    1018    1039 .. 0.77
   4 ?    2.1   0.0       0.2     2e+02      16      24 ..    1076    1084 ..    1075    1084 .. 0.91
   5 ?   -0.4   0.0       1.2   1.2e+03      15      24 ..    1199    1208 ..    1197    1208 .. 0.86
   6 ?    4.9   0.0     0.026        26      15      24 ..    1240    1249 ..    1236    1254 .. 0.84
   7 ?    2.5   0.0      0.15   1.5e+02      15      24 ..    1333    1342 ..    1329    1342 .. 0.88
   8 ?    0.1   0.0      0.85   8.4e+02      12      25 ..    1372    1385 ..    1371    1388 .. 0.86

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.092
                 EE-TTSSEEEEEEE CS
        PD40  15 sfSPDGkrlaFsSd 28 
                 +fSP+G+ +a sS+
  EEA19942.1 925 AFSPNGRLIASSSY 938
                 8*******997666 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.075
                 EEEEE-TTSSEEE CS
        PD40  12 gaPsfSPDGkrla 24 
                 ++++fSP+G+ l+
  EEA19942.1 964 ESIAFSPNGRLLV 976
                 789******9885 PP

  == domain 3  score: 3.4 bits;  conditional E-value: 0.077
                  .EEEEEE-TTSSEEE CS
        PD40   10 negaPsfSPDGkrla 24  
                  ++ + +fSPDG  la
  EEA19942.1 1025 PISSVAFSPDGELLA 1039
                  677889*****8776 PP

  == domain 4  score: 2.1 bits;  conditional E-value: 0.2
                  E-TTSSEEE CS
        PD40   16 fSPDGkrla 24  
                  fSPDG+ la
  EEA19942.1 1076 FSPDGRLLA 1084
                  9*****986 PP

  == domain 5  score: -0.4 bits;  conditional E-value: 1.2
                  EE-TTSSEEE CS
        PD40   15 sfSPDGkrla 24  
                  +fSPD + la
  EEA19942.1 1199 AFSPDSRLLA 1208
                  8****99886 PP

  == domain 6  score: 4.9 bits;  conditional E-value: 0.026
                  EE-TTSSEEE CS
        PD40   15 sfSPDGkrla 24  
                  +fSPDG+ la
  EEA19942.1 1240 AFSPDGQLLA 1249
                  8******998 PP

  == domain 7  score: 2.5 bits;  conditional E-value: 0.15
                  EE-TTSSEEE CS
        PD40   15 sfSPDGkrla 24  
                  +fSP+G++la
  EEA19942.1 1333 AFSPNGQMLA 1342
                  8*******97 PP

  == domain 8  score: 0.1 bits;  conditional E-value: 0.85
                  EEEEE-TTSSEEEE CS
        PD40   12 gaPsfSPDGkrlaF 25  
                  g+++fSP+ + la+
  EEA19942.1 1372 GSITFSPNSQLLAI 1385
                  579******99986 PP

>> SGL  SMP-30/Gluconolactonase/LRE-like region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.0      0.14   1.4e+02      43     101 ..     922     976 ..     911     985 .. 0.61
   2 !   15.0   0.0   1.4e-05     0.014       6     138 ..     986    1137 ..     966    1141 .. 0.71
   3 ?    0.6   0.0      0.34   3.4e+02     139     188 ..    1198    1245 ..    1197    1254 .. 0.79
   4 ?    0.9   0.0      0.29   2.9e+02       7      74 ..    1285    1362 ..    1282    1372 .. 0.72
   5 ?    1.3   0.0      0.22   2.1e+02      23      79 ..    1390    1448 ..    1374    1458 .. 0.76

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.14
         SGL  43 vGaiaprkdgrlvvasksglall..dlasgeletladeeedekpllrfNDgvvdpdGrlwf 101
                 v++++  ++grl++ s+++  +   d+++g+l+  +++      + r+  ++++p+Grl +
  EEA19942.1 922 VSVAFS-PNGRLIASSSYDGTIKlwDPDTGALKHTLESH-----KERVESIAFSPNGRLLV 976
                 455555.67777777766544333477777777777662.....34555666666666544 PP

  == domain 2  score: 15.0 bits;  conditional E-value: 1.4e-05
         SGL    6 vwdeeegaLlwv..Dilgqrihrldpatgketvldtpe.svGaiaprkdgrlvv.asksglall.dlasgeletladeeedekpllrfNDgvvdpdG 97  
                  +wd ++gaL ++  D  g++ +++++ +g++ v++t   +++++a  +dg+l++ ++++g + + d+a+g+le +++  +++ +l+r+  + ++pdG
  EEA19942.1  986 LWDSDTGALKYTvdDPHGRSFFEINNPNGATFVHHTGPpPISSVAFSPDGELLAsGANDGSVKFwDPATGALERILQT-KSR-ELHRVDSVCFSPDG 1080
                  57777777766555556666777777777777777766688888887999988854555555556************9.455.8************* PP

         SGL   98 rlwfGtmgdeeakgeev...............galyrldpdgklervl.ddltipNG 138 
                  rl +   +d++ k  ++               ga++r+  +  +++++  ++  +NG
  EEA19942.1 1081 RLLAAGSSDGTIKLWDPvtgvlnhtmwdysnkGAVFRMAFSPDARLLAsCHIDGSNG 1137
                  *88877777666655556666667777777777777766664443333245666666 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.34
         SGL  139 lawspdgktlYlaDsltrkiwaydvdaeggklsnrrvfadlkkgegepDG 188 
                  +a+spd++ l  aD    k+w  d+ a+++ l++   ++    +   pDG
  EEA19942.1 1198 VAFSPDSRLLASADGNSIKLWDLDMGAPEPILNAHADMVYSVAFS--PDG 1245
                  69***********************99999776666554333333..666 PP

  == domain 4  score: 0.9 bits;  conditional E-value: 0.29
         SGL    7 wdeeegaLlwvDilgqrihrldpatgketv........ldtpesvGaiaprkdgrlvvasksglall..dlasgelet 74  
                   +  +++Ll + + ++++  +dpatg  ++        l++ +sv+++a  ++g++++a +++ ++   dl++g+++ 
  EEA19942.1 1285 IFSHDNRLLASGVSEGTVRLWDPATGILKHtlkgpsadLRMRSSVTSLAFSPNGQMLAAGTNNHIIDiwDLTTGTVKH 1362
                  556789999999999999999999998887777777666666677777776887777754433332224888888765 PP

  == domain 5  score: 1.3 bits;  conditional E-value: 0.22
         SGL   23 rihrldpatgketvldtpe..svGaiaprkd.grlvvasksglalldlasgeletladee 79  
                  +i+ +d+atg+ +++  ++    +++++ +d + lv +s+ ++ ++d+++g+le ++d++
  EEA19942.1 1390 EINLWDMATGTLKHTVEENraLQSIAFL-PDsKLLVSGSTAHIKFWDYTTGALEHIIDSF 1448
                  6777888877655433333458888888.55378888999999999*******9999985 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.4   0.0   2.7e-09   2.6e-06       3     132 ..     380     525 ..     379     553 .. 0.75

  Alignments for each domain:
  == domain 1  score: 27.4 bits;  conditional E-value: 2.7e-09
                 EEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-......-HCHHHCCCCTS--SSS-C........CHHHHCCSCCCEE...... CS
       NACHT   3 vilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgna...rsladllfsqlpepaapvse........vwavllelperlL...... 84 
                  +l+G aG GK+t  + +a+  +++ l +     +Ff++ +e  r +++   +++a++lf+  pe  +++ +          + l e+++rl       
  EEA19942.1 380 FWLNGLAGTGKSTISRTVARNFQKQGLLG----ASFFFKRGEGDRGNATrffPTIARQLFAGIPEVCDAILQvikdhpriSAKPLKEQFDRLIkqplad 474
                 59************************988....589999999999877788888888888888888888888666666664444444444444777777 PP

                 ............EEEE-STT-SS-TCH.........HHHHHCTTTTT--EEEEEEECCCH CS
       NACHT  85 ............lilDglDelvtdlgqkekqpvrtlLselirkkllpeasllltvrpral 132
                             +++D+lDe++ +++       r+ +++l r     + ++++t+rp+  
  EEA19942.1 475 lyqlkgqrpplvIVIDALDECEGENDI------RVIIQQLPRS---VCLRFFITSRPELP 525
                 799999999999**********96666......4444443333...33456889998766 PP

>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.1   1.2e-08   1.2e-05       3     221 ..      10     265 ..       8     282 .. 0.65

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 1.2e-08
                 EEEESSHHHHHHHHHHEEEEEEEEEE.....TTEEEEEEEETTEEEEEEE--...SSHHHHHHHHHHHHHHHC.--SEEEEEEEEEES..STTT-TT-E CS
   PNP_UDP_1   3 aiivgspgevellaespleetpfgre....grgfkfvtGtlkgkpvvivstG...iGkpnaavvaeirllkef.gvkaiiriGtaGgl..npdlkvGDv 91 
                 + i++ + e+ + ++  l++++ ++e    +   ++++G+++g++vvi+       G+++aa   +  +l++f ++   +++G+ Gg+  ++d+++GD+
  EEA19942.1  10 GWICALETEYVAARAF-LDTKHTRPEklspNDNNHYTLGEIGGHKVVIAVVPdreYGTSSAA-EVARDMLHSFpNIQFGLMVGIGGGVplKHDIRLGDI 106
                 5678888777777777.5555555557888999*********************88******.99999***9965555699999999999********* PP

                 EEEEEEEESSSCCGCCTHHCC.........................TCCCCTTSSEE--HHHHHHHHHCHHTTT......................... CS
   PNP_UDP_1  92 vipddainfdgrsplygpkee.........................gqyfpdsydapadpelrallkeaaealg......................... 140
                 ++++   ++ g+ ++ + ke                                               ++ e++g                         
  EEA19942.1 107 IVSSPRNGHGGLLQYDFGKELqgkefhqtgflnqpppilrtavaglQ--------------------AQYEEEGhqlkeriqsllegnkrlkrkyerpp 185
                 *****767777777666666677777655555555555444444331....................32233333333333333344444445556544 PP

                 ....TTEEEEEEEEESESS-CHHHHHH........HHHHTC-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTBETTCTCH.HCCCHHHHHH CS
   PNP_UDP_1 141 ....ikvhrGvvatadgfyaeteaelr........llrrlgadaveMEtaavaqlArelgipfaairvvsdlaaggadaeatheeveefaqea 221
                     + ++ G   +  +   +   +++        +  ++ + + eME+a +      ++ p+++ir+v d+a+ + ++e+        +  a
  EEA19942.1 186 fesdRLYESGFAHSDPQANCDELCDISklillsimIATSQDVLCFEMEAAGLI-----NHFPCLVIRGVCDYADSHKSKEW--------QGYA 265
                 44446666666666666666664444455545564555555999999999875.....89999999999996666333333........2222 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0       1.9   1.9e+03      54      95 ..     244     290 ..     237     335 .. 0.66
   2 !   25.1   0.0     2e-08     2e-05      24     146 ..     377     494 ..     359     523 .. 0.68

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 1.9
      AAA_16  54 iflrgkcdqlesa.....ipysalaqalareellrqlldeaesaele 95 
                 +++rg cd  +s        y+a a a+ +++ll+q+  +  ++e++
  EEA19942.1 244 LVIRGVCDYADSHkskewQGYAAMAAAAYARDLLNQIVPQRVDSERR 290
                 56778888774443445566777555555779999998884443332 PP

  == domain 2  score: 25.1 bits;  conditional E-value: 2e-08
      AAA_16  24 pelvllsGesGvGKsslvrellralekd.....ggiflrgkcdqlesaipysa.laqalareellrqlldeaesaeleawrekleealaavpelagaea 116
                  ++  l G +G+GKs++ r+++r ++k+      ++f rg+ d+   a+++ + +a++l +   + +++d+   +   ++++   + l+          
  EEA19942.1 377 KCIFWLNGLAGTGKSTISRTVARNFQKQgllgaSFFFKRGEGDRG-NATRFFPtIARQL-F-AGIPEVCDA-ILQVIKDHPRISAKPLK---------- 461
                 3788999*********************88843233355555554.4445444455555.3.445555555.33355555555555555.......... PP

      AAA_16 117 srllellkrll.allsrder..plvlvlDdlqw 146
                 +++ +l+k+ l +l++ +++  plv+v+D l+ 
  EEA19942.1 462 EQFDRLIKQPLaDLYQLKGQrpPLVIVIDALDE 494
                 88888888888766665444446********95 PP

>> Proteasome_A_N  Proteasome subunit A N-terminal signature
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0     0.064        64       8      14 ..     926     932 ..     924     933 .. 0.90
   2 ?    4.1   0.0     0.037        37       8      15 ..     968     975 ..     965     975 .. 0.89
   3 ?    3.0   0.0     0.086        85       7      15 ..    1030    1038 ..    1027    1038 .. 0.83
   4 !    6.5   0.0    0.0065       6.4       8      15 ..    1076    1083 ..    1073    1083 .. 0.91
   5 ?    3.0   0.0     0.084        84       8      15 ..    1241    1248 ..    1238    1248 .. 0.87
   6 ?   -2.9   0.0       5.8   5.8e+03       8      12 ..    1334    1338 ..    1333    1339 .. 0.88
   7 ?   -3.5   0.1       9.2   9.2e+03       7      10 ..    1375    1378 ..    1374    1379 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.064
  Proteasome_A_N   8 FSPdGRL 14 
                     FSP GRL
      EEA19942.1 926 FSPNGRL 932
                     ******9 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.037
  Proteasome_A_N   8 FSPdGRLf 15 
                     FSP GRL+
      EEA19942.1 968 FSPNGRLL 975
                     ******96 PP

  == domain 3  score: 3.0 bits;  conditional E-value: 0.086
  Proteasome_A_N    7 tFSPdGRLf 15  
                       FSPdG L+
      EEA19942.1 1030 AFSPDGELL 1038
                      5*****985 PP

  == domain 4  score: 6.5 bits;  conditional E-value: 0.0065
  Proteasome_A_N    8 FSPdGRLf 15  
                      FSPdGRL+
      EEA19942.1 1076 FSPDGRLL 1083
                      ******96 PP

  == domain 5  score: 3.0 bits;  conditional E-value: 0.084
  Proteasome_A_N    8 FSPdGRLf 15  
                      FSPdG L+
      EEA19942.1 1241 FSPDGQLL 1248
                      *****995 PP

  == domain 6  score: -2.9 bits;  conditional E-value: 5.8
  Proteasome_A_N    8 FSPdG 12  
                      FSP G
      EEA19942.1 1334 FSPNG 1338
                      ****9 PP

  == domain 7  score: -3.5 bits;  conditional E-value: 9.2
  Proteasome_A_N    7 tFSP 10  
                      tFSP
      EEA19942.1 1375 TFSP 1378
                      9*** PP

>> Frtz  WD repeat-containing and planar cell polarity effector protein Fritz
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.0     0.053        53     261     295 ..     962     996 ..     919    1001 .. 0.78
   2 ?    2.8   0.0      0.03        30     262     327 ..    1026    1096 ..    1023    1108 .. 0.67
   3 ?   -1.5   0.0      0.58   5.7e+02     258     335 ..    1191    1269 ..    1189    1306 .. 0.64
   4 !    8.2   0.0   0.00069      0.69     257     341 ..    1324    1408 ..    1319    1424 .. 0.85

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.053
        Frtz 261 qvislafnpdedkLllGceDssviLydeerkitkl 295
                 +v s af+p+   L+ G+ D+++ L+d++++  k+
  EEA19942.1 962 RVESIAFSPNGRLLVSGSYDGTIKLWDSDTGALKY 996
                 56778888888888888888888888888776655 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.03
        Frtz  262 vislafnpdedkLllGceDssviLydeerkitklv.ka...ev.vPsliswhpdsaillvasergelqifD 327 
                  + s+af+pd + L  G++D+sv ++d  ++  + + ++   e+ + + + + pd+ +l  +s+ g ++++D
  EEA19942.1 1026 ISSVAFSPDGELLASGANDGSVKFWDPATGALERIlQTksrELhRVDSVCFSPDGRLLAAGSSDGTIKLWD 1096
                  67888999999999999999999988766543222133001331346677778888888888888888877 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 0.58
        Frtz  258 lraqvislafnpdedkLllGceDssviLydeerkitklv...kaevvPsliswhpdsaillvasergelqifDlaLspiri 335 
                  l   v s+af+pd  +Ll  +  +s+ L+d +++  + +   +a++v   +++ pd+ +l  +s    +++++ +  ++++
  EEA19942.1 1191 LSYLVLSVAFSPDS-RLLASADGNSIKLWDLDMGAPEPIlnaHADMV-YSVAFSPDGQLLASCSRDRTIKLWETSTGALKH 1269
                  55566777777754.45555555567777777766543221144444.446666777777666666666666655555554 PP

  == domain 4  score: 8.2 bits;  conditional E-value: 0.00069
        Frtz  257 PlraqvislafnpdedkLllGceDssviLydeerkitklv.kaevvP.sliswhpdsaillvasergelqifDlaLspiriqllsed 341 
                   +r+ v slaf+p+ + L  G+++  + ++d ++++ k   + +v+    i++ p+s +l ++s r e+ ++D+a  ++++ +  e+
  EEA19942.1 1324 RMRSSVTSLAFSPNGQMLAAGTNNHIIDIWDLTTGTVKHSlELHVRAvGSITFSPNSQLLAIGS-RYEINLWDMATGTLKHTV-EEN 1408
                  699******************************9998877678887625799999999999986.78*********9998853.455 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       1.6   1.6e+03     117     145 ..     786     814 ..     775     846 .. 0.83
   2 !    5.6   0.0    0.0083       8.3       3      66 ..     921     985 ..     919     997 .. 0.89
   3 ?    2.8   0.0     0.062        62       3      43 ..    1236    1276 ..    1234    1301 .. 0.86
   4 ?    4.0   0.0     0.027        27       3      59 ..    1329    1385 ..    1327    1438 .. 0.69

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 1.6
   WD40_like 117 llgqsseIkeikiennkiysLsesafivf 145
                  + + ++I++++i+ + +y+  + +f+ +
  EEA19942.1 786 WIHHITKILDVIIQVGHVYAFLQVHFLHW 814
                 467899**************999999876 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0083
   WD40_like   3 iYsidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvklldddlilv.vtlDGtil 66 
                 + s+ +s++g li+  + d ++++ + +++ ++  +es ++ v  + +  +  +lv ++ DGti 
  EEA19942.1 921 VVSVAFSPNGRLIASSSYDGTIKLWDPDTGALKHTLESHKERVESIAFSPNGRLLVsGSYDGTIK 985
                 66999**************************************99999999977773699***94 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.062
   WD40_like    3 iYsidiskkgslilyGgkddkctvlkleslesvsivesfed 43  
                  +Ys+ +s++g+l++  ++d ++++ ++ ++ ++  ++ +e 
  EEA19942.1 1236 VYSVAFSPDGQLLASCSRDRTIKLWETSTGALKHTLNALEG 1276
                  9****************************999888877765 PP

  == domain 4  score: 4.0 bits;  conditional E-value: 0.027
   WD40_like    3 iYsidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvklldddlilvv 59  
                  + s+ +s++g++++ G +++ + + +l +++++ ++e     v  + +  + ++l  
  EEA19942.1 1329 VTSLAFSPNGQMLAAGTNNHIIDIWDLTTGTVKHSLELHVRAVGSITFSPNSQLLAI 1385
                  6688999**********************9999988876666655555555555555 PP

>> Cytochrom_D1  Cytochrome D1 heme domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.5   0.0   0.00062      0.62      31     109 ..     914     992 ..     909    1001 .. 0.82
   2 ?    1.2   0.0       0.1     1e+02      14      63 ..    1044    1096 ..    1040    1106 .. 0.78
   3 ?    2.9   0.0     0.033        33      12      62 ..    1210    1260 ..    1204    1330 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00062
                   EE-STTEEEEEE-TT.SSEEEEEETTSEEEEEESSSSSEEEEEE-SSEE.EEEEE--TTSEEEEEEEETTEEEEEETTT- CS
  Cytochrom_D1  31 letgyalHisrvfasdgRyvyvigRDgkvtliDLwakeivaevkiGlna.rsvavSqddryvivgnYlPgqlvildaetL 109
                   le++    +s+ f+++gR++   + Dg+++l D  +    ++++   +   s+a S ++r+++ g+Y  g++++ d++t 
    EEA19942.1 914 LEGHSGSVVSVAFSPNGRLIASSSYDGTIKLWDPDTGALKHTLESHKERvESIAFSPNGRLLVSGSYD-GTIKLWDSDTG 992
                   555555568999*****************9999988888888888777526899*************6.89999999985 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.1
                    GTEEEEEETTT-SEEEEEE-ST.TEEE..EEE-TT.SSEEEEEETTSEEEEEE CS
  Cytochrom_D1   14 agkvalldgdskeilavletgy.alHi..srvfasdgRyvyvigRDgkvtliD 63  
                    +g+v+  d  +     +l+t+  +lH   s+ f++dgR++   + Dg+++l D
    EEA19942.1 1044 DGSVKFWDPATGALERILQTKSrELHRvdSVCFSPDGRLLAAGSSDGTIKLWD 1096
                    67777777777777777777642678444999****************99987 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.033
                    GGGTEEEEEETTT-SEEEEEE-STTEEEEEE-TT.SSEEEEEETTSEEEEE CS
  Cytochrom_D1   12 rdagkvalldgdskeilavletgyalHisrvfasdgRyvyvigRDgkvtli 62  
                    +d  +++l d d      +l+++ ++  s+ f++dg ++   +RD +++l 
    EEA19942.1 1210 ADGNSIKLWDLDMGAPEPILNAHADMVYSVAFSPDGQLLASCSRDRTIKLW 1260
                    56678999999999999999*************************887654 PP

>> APS_kinase  Adenylylsulphate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.1   1.8e-05     0.018       3      31 ..     378     406 ..     376     412 .. 0.92

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.8e-05
                 EEEEEESSTTSSHHHHHHHHHHHHHHTT- CS
  APS_kinase   3 vvvwltGlsgsGKstianalekkLvekgi 31 
                 +++wl Gl+g+GKsti+++++++ +++g 
  EEA19942.1 378 CIFWLNGLAGTGKSTISRTVARNFQKQGL 406
                 899*********************99984 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   0.00039      0.39      17      46 ..     376     405 ..     371     414 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00039
      AAA_30  17 gdrvavltGpAGtGKttalkalreaweaag 46 
                 g+ +  l+G AGtGK+t+ +++++ ++++g
  EEA19942.1 376 GKCIFWLNGLAGTGKSTISRTVARNFQKQG 405
                 56677899**************99998887 PP

>> K1  K1 glycoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.2   0.00036      0.36      42     101 ..     793     852 ..     781     862 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00036
          K1  42 tlfvmkevkstylyiqehllvfmtlvaligtmcgilgtiifahcqkqrdsnktvpqqlqd 101
                  l v+ +v   y ++q h+l +m +++ +g +  ++g i + +   q d n  + + l+d
  EEA19942.1 793 ILDVIIQVGHVYAFLQVHFLHWMEVMCTLGLVSEVIGGINILKSTLQDDDNLQISEFLDD 852
                 5778899999*****************************************999988887 PP

>> KAP_NTPase  KAP family P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   0.00031      0.31     170     189 ..     477     499 ..     379     506 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00031
  KAP_NTPase 170 a...lqkrlVvviDdLDrcetee 189
                 +   +  +lV+viD+LD ce e+
  EEA19942.1 477 QlkgQRPPLVIVIDALDECEGEN 499
                 24449999************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1545 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       522  (0.0291148); expected 358.6 (0.02)
Passed bias filter:                      515  (0.0287244); expected 358.6 (0.02)
Passed Vit filter:                        89  (0.00496402); expected 17.9 (0.001)
Passed Fwd filter:                        18  (0.00100396); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              18  [number of targets reported over threshold]
# CPU time: 1.13u 0.35s 00:00:01.48 Elapsed: 00:00:00.56
# Mc/sec: 8281.93
//
Query:       EEA19943.1  [L=701]
Description: protease S8 tripeptidyl peptidase I, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.4e-47  160.8   0.0    5.8e-47  159.6   0.0    1.6  2  Pro-kuma_activ  Pro-kumamolisin, activation domain
    0.00015   21.2   0.3    0.00028   20.2   0.3    1.4  1  Peptidase_S8    Subtilase family
  ------ inclusion threshold ------
        0.1   13.0   0.0       0.29   11.6   0.0    1.7  1  SecD-TM1        SecD export protein N-terminal TM region


Domain annotation for each model (and alignments):
>> Pro-kuma_activ  Pro-kumamolisin, activation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  159.6   0.0   9.7e-51   5.8e-47       2     140 ..      40     180 ..      39     182 .. 0.98
   2 ?   -2.9   0.0       1.2   7.4e+03     100     131 ..     277     307 ..     267     317 .. 0.71

  Alignments for each domain:
  == domain 1  score: 159.6 bits;  conditional E-value: 9.7e-51
  Pro-kuma_activ   2 gwtkrgraasstllpvrigLkqnnlekledflmdvsdpkspnygkhltaeevaelfapseeaidaVrnwLessgiaasr..hsdtkgwiafsatv 94 
                     +wtkr+r++ ++llp+rigL+q+nle+++++l dvs+p+s+nygkh+t+eev + f+ps++++++V+ wL+++gi+ +r  hsd++gw+af at 
      EEA19943.1  40 RWTKRDRVPRDKLLPMRIGLAQSNLEEMYQHLLDVSHPDSANYGKHWTPEEVIKAFQPSDKTVESVKTWLTDNGISSKRitHSDNRGWLAFFATP 134
                     8********************************************************************************************** PP

  Pro-kuma_activ  95 aqverllktsfeaYshkkgssslarcdeyslPealknyvdyihptd 140
                      ++erllkt+f+ ++   ++  + +cdey++P +lk++vd+++p  
      EEA19943.1 135 DEAERLLKTEFHEFEDSVTGGIMPACDEYHVPHHLKEHVDFVTPGI 180
                     ***************999************************9975 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.2
  Pro-kuma_activ 100 llktsfeaYshkkgssslarcdeyslPealkn 131
                     +++++++ Y+++     + ++ ++++P+  + 
      EEA19943.1 277 IFESELQFYTQQ-DLDLFFANFTPHIPKGTHP 307
                     799999999965.5666666677888887665 PP

>> Peptidase_S8  Subtilase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.3   4.7e-08   0.00028     122     261 ..     415     631 ..     398     642 .. 0.83

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 4.7e-08
                   -SEEEE-EE.SCETTCHHCHHHHHHHHHHHH.CC.T-EEEEE--SS-T-HH............EEE-TTCEECTTTSTTCEEEEEES.......... CS
                   xxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx............xxxxxxxxxxxxxxxxxxxxxxxx.......... RF
  Peptidase_S8 122 vdvinmslg.estslpktgrsiealainravnkk.gvlvviSaGNngktgs............slqagspvgtpstsknvitvgayt.......... 194
                     vi++s+g ++ +lp ++++ +  ++++a+    gv + +++G +g ++             s+ +  +   p t+  v+ vga++          
    EEA19943.1 415 TNVISVSYGgQEVDLPLSYQRRQ--CLEYAKLGLqGVSFLFASGDSGVSNYpnsgdgptgcigSKLNVFNPTWPNTCPYVTNVGATKvypgktvwdp 509
                   459******66777888888777..7777776666************5555667767888776666666666799999******************* PP

                   .......................................................................TTSSB-TT--B-TT.......-EEEE CS
                   .......................................................................xxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8 195 .......................................................................tegkiapfSsrGpssdgklkpdivap 220
                                                                                          + g    + +      g+  pd++a 
    EEA19943.1 510 esavfdpagypysanyssgggfsnvfpipdyqrkavatffkkhnppypyysalapetndiqqmididslvgNTGG--IYNRI-----GRGVPDVAAN 599
                   **********************************************************88887766666333333..33333.....34449***** PP

                   -S-CCCCCCCCCHHHTTTHHEEEE-SHHHCHHHHHHHHHHH CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8 221 GgnivstwsrqsnnsaglssyqsmsGTSmAsPnaagaaAll 261
                   G n +  ++  +        y +  GTS+++P  a+++  +
    EEA19943.1 600 GDN-IMVYNGGN--------YSLSGGTSASTPIFAAVINRI 631
                   ***.88899999........99***********99998766 PP

>> SecD-TM1  SecD export protein N-terminal TM region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   4.9e-05      0.29      44      83 ..      96     136 ..      90     147 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 4.9e-05
    SecD-TM1  44 kvdeatlskveqaLkeagievksielenes.llvrfestdq 83 
                 + +++t+++v++ L+++gi+ k+i+ ++++  l+ f+++d+
  EEA19943.1  96 QPSDKTVESVKTWLTDNGISSKRITHSDNRgWLAFFATPDE 136
                 6688999*****************77666537888887775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (701 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       324  (0.0180713); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.64u 0.26s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 4634.24
//
Query:       EEA19944.1  [L=155]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.2e-07   30.2   0.0    5.8e-07   29.7   0.0    1.2  1  Ribonucleas_3_3  Ribonuclease-III-like
    1.9e-05   25.3   0.0    8.6e-05   23.1   0.0    1.9  1  Ribonuclease_3   Ribonuclease III domain


Domain annotation for each model (and alignments):
>> Ribonucleas_3_3  Ribonuclease-III-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.7   0.0   6.5e-11   5.8e-07      20     120 ..      43     138 ..      34     144 .. 0.82

  Alignments for each domain:
  == domain 1  score: 29.7 bits;  conditional E-value: 6.5e-11
  Ribonucleas_3_3  20 ghNerLefLGdavLklsvseyllekaekdegeltklraslvseeslaeiAkelgLgkvlrlrkgeeetegsgrekvladaleAliGAiyldkga 113
                      ++N+rL++ Gd++ + ++ +  +e +   +++ t  r++++ +  l + ++++gL+ +l l+ g++e   s    ++a+ +eA++GA++ld+g 
       EEA19944.1  43 PKNTRLAVYGDSAAAHYMCRRWVEMPL-TKEQWTGIRKHVLGNSILGRTGIRMGLNYCLNLNPGTTE--VS--HDMMATSVEAILGAVHLDGGD 131
                      78***********99999988877765.55677888889**********************664444..33..4599**************998 PP

  Ribonucleas_3_3 114 evaqefv 120
                      ++  +++
       EEA19944.1 132 QALASVM 138
                      8877665 PP

>> Ribonuclease_3  Ribonuclease III domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.1   0.0   9.5e-09   8.6e-05       2     105 .]      47     130 ..      46     130 .. 0.91

  Alignments for each domain:
  == domain 1  score: 23.1 bits;  conditional E-value: 9.5e-09
                     HHHHHHHHHHHHHHHHHHHHHCTTSSHHHHHHHHHHHTSHHHHHHHHHCTTCHCCHCHH..............HHCCSTTCHCTSHHHHHHHHHH CS
  Ribonuclease_3   2 rLeflGDavlklaittylfetypdahegrlsklrsklvsnenlarlakklglpkflrasefdpprnwlppgyklsddekedddadkvladvvEAl 96 
                     rL+  GD+   ++++++ +e  p + +++ + +r+ ++ n  l r + ++gl+  l+                l+ +  e   +   +a+ vEA+
      EEA19944.1  47 RLAVYGDSAAAHYMCRRWVE-MP-LTKEQWTGIRKHVLGNSILGRTGIRMGLNYCLN----------------LNPGTTE--VSHDMMATSVEAI 121
                     9*******************.89.9999****************************9................5555554..56689******** PP

                     HHHHHHHCT CS
  Ribonuclease_3  97 iGaiyldsg 105
                     +Ga++ld+g
      EEA19944.1 122 LGAVHLDGG 130
                     ******987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (155 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       351  (0.0195772); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.39u 0.24s 00:00:00.63 Elapsed: 00:00:00.39
# Mc/sec: 1204.87
//
Query:       EEA19945.1  [L=455]
Description: RING finger protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.3e-12   47.7  18.4    3.7e-11   43.1   1.0    3.6  3  IBR             IBR domain, a half RING-finger domain
     0.0019   18.0   7.1     0.0019   18.0   7.1    2.6  2  zf-C3HC4        Zinc finger, C3HC4 type (RING finger)
  ------ inclusion threshold ------
      0.025   14.3   8.8        3.8    7.3   5.7    3.3  3  DNA_RNApol_7kD  DNA directed RNA polymerase, 7 kDa subunit
        0.2   11.3   0.1        0.2   11.3   0.1    3.6  4  Sgf11           Sgf11 (transcriptional regulation protein)
        1.2    9.9   8.0        9.8    6.9   0.8    3.5  3  zf-ISL3         zinc-finger of transposase IS204/IS1001/IS109
        1.2    9.3   6.6       0.74   10.0   0.3    2.6  2  TRAF6_Z2        TNF receptor-associated factor 6 zinc finger 
        3.1    8.0  10.5        5.3    7.2   1.9    3.3  3  UPF0547         Uncharacterised protein family UPF0547
        3.6    8.0  12.3       0.11   12.9   4.6    2.4  2  DUF3280         Protein of unknown function (DUF2380)
        4.6    7.5  11.0        2.2    8.5   0.7    3.7  3  zf-RING_7       C4-type zinc ribbon domain
        5.3    7.2  14.2        3.1    8.0   1.0    3.7  3  zf-UDP          Zinc-binding RING-finger
        6.6    6.5  16.5         12    5.6  16.5    1.4  1  RR_TM4-6        Ryanodine Receptor TM 4-6


Domain annotation for each model (and alignments):
>> IBR  IBR domain, a half RING-finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   4.1       3.5   5.7e+03      26      46 ..     174     201 ..     138     203 .. 0.69
   2 !   43.1   1.0   2.3e-14   3.7e-11       1      62 []     218     279 ..     218     279 .. 0.91
   3 !   15.2   0.4   1.2e-05     0.019      11      40 ..     399     427 ..     389     437 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 3.5
         IBR  26 Ceaiieksegcks........vtCskCgf 46 
                 C+  i+ks + ++        ++C++C++
  EEA19945.1 174 CNICISKSIK-SDletriwdqIRCPECQT 201
                 4433333333.113345666678888875 PP

  == domain 2  score: 43.1 bits;  conditional E-value: 2.3e-14
         IBR   1 ekyeklklkkslesdpnlkwCprpdCeaiiekseg..cksvtCskCgfefCfnCkkewHeglsC 62 
                 e+ye+l++++ + sd+n++wC   +C+    +++g  +  v+C +Cgf+ C+ +  +wH+gl+C
  EEA19945.1 218 ERYERLSFRSAVGSDENFIWCQ--QCDFGQLHEKGasEPIVRCLNCGFRSCYLHAGPWHSGLTC 279
                 79*******************9..***999888885344499********************** PP

  == domain 3  score: 15.2 bits;  conditional E-value: 1.2e-05
         IBR  11 sles.dpnlkwCprpdCeaiieksegcksvt 40 
                 s+e+ ++++k+Cp  +Ce++iek+ gc+++t
  EEA19945.1 399 SMETmKQTTKQCP--GCERPIEKNRGCDHMT 427
                 466767789****..************9986 PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   7.1   1.2e-06    0.0019       1      41 []     146     199 ..     146     199 .. 0.94
   2 ?   -0.2   0.4      0.58   9.4e+02      33      41 .]     405     413 ..     398     425 .. 0.78

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 1.2e-06
                 -TTT-S--SS-E......E-TTS--..B-CHHHHHHHHC......TSSB--TTT CS
    zf-C3HC4   1 CpiCleeakepn.....elleCkHs..fCskCirkilks......rkkvkCPlC 41 
                 C+iC e +++++      ++ C H+  +C+ Ci+k +ks        +  CP+C
  EEA19945.1 146 CNICVEDFSNTVtrpawISIACAHEpsVCNICISKSIKSdletriWDQIRCPEC 199
                 ************************999**************998866677***9 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.58
                 TSSB--TTT CS
    zf-C3HC4  33 rkkvkCPlC 41 
                 +++++CP C
  EEA19945.1 405 QTTKQCPGC 413
                 566779988 PP

>> DNA_RNApol_7kD  DNA directed RNA polymerase, 7 kDa subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.1     0.006       9.8      16      23 ..     192     199 ..     183     205 .. 0.79
   2 ?   -1.3   0.1       1.2   1.9e+03      16      23 ..     234     241 ..     231     249 .. 0.81
   3 ?    7.3   5.7    0.0023       3.8      17      29 ..     255     267 ..     237     268 .. 0.79

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.006
                     S----SSS CS
  DNA_RNApol_7kD  16 dpiRCkeC 23 
                     d+iRC eC
      EEA19945.1 192 DQIRCPEC 199
                     89****** PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.2
                     S----SSS CS
  DNA_RNApol_7kD  16 dpiRCkeC 23 
                       i C++C
      EEA19945.1 234 NFIWCQQC 241
                     56889999 PP

  == domain 3  score: 7.3 bits;  conditional E-value: 0.0023
                     ----SSS-----B CS
  DNA_RNApol_7kD  17 piRCkeCGhRilY 29 
                     ++RC +CG+R+ Y
      EEA19945.1 255 IVRCLNCGFRSCY 267
                     58********988 PP

>> Sgf11  Sgf11 (transcriptional regulation protein)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.2       2.3   3.7e+03       4      10 ..     143     149 ..     141     150 .. 0.84
   2 ?   -1.6   0.2       1.3   2.1e+03       5      11 ..     194     200 ..     193     200 .. 0.82
   3 ?    3.7   0.1     0.029        47       3      11 ..     254     262 ..     252     264 .. 0.87
   4 ?   11.3   0.1   0.00012       0.2       6      23 ..     409     426 ..     404     427 .. 0.86

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 2.3
                 EEE-TTT CS
       Sgf11   4 yvtCpnC 10 
                 +++C++C
  EEA19945.1 143 LTSCNIC 149
                 679**** PP

  == domain 2  score: -1.6 bits;  conditional E-value: 1.3
                 EE-TTTS CS
       Sgf11   5 vtCpnCg 11 
                 ++Cp C+
  EEA19945.1 194 IRCPECQ 200
                 58****5 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.029
                 -EEE-TTTS CS
       Sgf11   3 eyvtCpnCg 11 
                 + v+C+nCg
  EEA19945.1 254 PIVRCLNCG 262
                 789*****7 PP

  == domain 4  score: 11.3 bits;  conditional E-value: 0.00012
                 E-TTTSSEEEGGGHHHHH CS
       Sgf11   6 tCpnCgRqiaasRFApHL 23 
                 +Cp C+R+i  +R + H+
  EEA19945.1 409 QCPGCERPIEKNRGCDHM 426
                 8************88886 PP

>> zf-ISL3  zinc-finger of transposase IS204/IS1001/IS1096/IS1165
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0     0.037        60       2      15 ..     193     206 ..     192     219 .. 0.79
   2 ?    6.9   0.8     0.006       9.8       3      37 ..     236     270 ..     235     270 .. 0.94
   3 ?    0.5   0.6      0.61     1e+03       4      11 ..     409     416 ..     406     434 .. 0.76

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.037
     zf-ISL3   2 phrCPnCgsktvvk 15 
                 ++rCP+C+    ++
  EEA19945.1 193 QIRCPECQTLLIYD 206
                 689****9876666 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.006
     zf-ISL3   3 hrCPnCgsktvvkhgkkerrvrhlpiggkrvyLrl 37 
                 ++C +C    ++ +g +e +vr l++g + +yL++
  EEA19945.1 236 IWCQQCDFGQLHEKGASEPIVRCLNCGFRSCYLHA 270
                 69****999************************96 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.61
     zf-ISL3   4 rCPnCgsk 11 
                 +CP+C ++
  EEA19945.1 409 QCPGCERP 416
                 7****987 PP

>> TRAF6_Z2  TNF receptor-associated factor 6 zinc finger 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   1.3      0.23   3.8e+02       5      10 ..     195     200 ..     193     202 .. 0.85
   2 ?   10.0   0.3   0.00045      0.74       5      23 ..     409     427 ..     408     429 .. 0.94

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.23
    TRAF6_Z2   5 eCPQCQ 10 
                  CP CQ
  EEA19945.1 195 RCPECQ 200
                 6***** PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00045
    TRAF6_Z2   5 eCPQCQraFQKnqlkeHil 23 
                  CP C r+  Kn+  +H++
  EEA19945.1 409 QCPGCERPIEKNRGCDHMT 427
                 5****************98 PP

>> UPF0547  Uncharacterised protein family UPF0547
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.2     0.016        25       2       8 ..     195     201 ..     194     203 .. 0.76
   2 ?   -1.3   0.1       1.5   2.5e+03      16      22 ..     257     263 ..     255     264 .. 0.80
   3 ?    7.2   1.9    0.0033       5.3       1      10 [.     408     417 ..     408     420 .. 0.92

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.016
     UPF0547   2 vCPeCea 8  
                 +CPeC++
  EEA19945.1 195 RCPECQT 201
                 5888876 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.5
     UPF0547  16 fCphCGy 22 
                 +C  CG+
  EEA19945.1 257 RCLNCGF 263
                 6988**9 PP

  == domain 3  score: 7.2 bits;  conditional E-value: 0.0033
     UPF0547   1 KvCPeCeakv 10 
                 K+CP+Ce+++
  EEA19945.1 408 KQCPGCERPI 417
                 9******987 PP

>> DUF3280  Protein of unknown function (DUF2380)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.2       1.4   2.3e+03      65      65 ..     119     119 ..      65     158 .. 0.52
   2 ?   12.9   4.6     7e-05      0.11      18      91 ..     358     435 ..     344     445 .. 0.63

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 1.4
     DUF3280  65 k 65 
                 +
  EEA19945.1 119 R 119
                 2 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 7e-05
     DUF3280  18 adqtaeearRlaavteqlreaLaesgryevvdlapaaaeie.....kesnlrkCngceadiArklgAdlvlvgevqKvS 91 
                 ++q++ee++R ++ ++q +e+++++ + +++  a ++ e +      ++  ++C gce+ i ++ g d++ + +v+K  
  EEA19945.1 358 ERQRTEEEERARETKRQ-QEKIRKEDQERLLMDARRQRENAlsmetMKQTTKQCPGCERPIEKNRGCDHMTYSVVRKFK 435
                 33355555555544444.444444444444433333333333565545559*************************975 PP

>> zf-RING_7  C4-type zinc ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.7    0.0013       2.2       4      33 .]     173     203 ..     171     203 .. 0.83
   2 ?    3.5   0.7     0.051        83      20      30 ..     251     262 ..     231     262 .. 0.83
   3 ?   -0.0   0.1      0.65   1.1e+03      23      31 ..     407     415 ..     388     415 .. 0.60

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.0013
                 TT--B--CCHHHHHCCS..TB-EE-TTT--EE CS
   zf-RING_7   4 GChmelppqvlselrag..devvtCpeCGRIL 33 
                  C++ ++ +  s+l     d+ ++CpeC+ +L
  EEA19945.1 173 VCNICISKSIKSDLETRiwDQ-IRCPECQTLL 203
                 688888888889998888887.******9776 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.051
                 S.TB-EE-TTT- CS
   zf-RING_7  20 g.devvtCpeCG 30 
                 + + +v+C +CG
  EEA19945.1 251 AsEPIVRCLNCG 262
                 2477*******9 PP

  == domain 3  score: -0.0 bits;  conditional E-value: 0.65
                 -EE-TTT-- CS
   zf-RING_7  23 vvtCpeCGR 31 
                   +Cp C R
  EEA19945.1 407 TKQCPGCER 415
                 358**9977 PP

>> zf-UDP  Zinc-binding RING-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   1.0    0.0019       3.1      10      59 ..     145     202 ..     139     212 .. 0.81
   2 ?    1.2   0.9      0.25   4.1e+02      11      38 ..     238     266 ..     231     271 .. 0.70
   3 ?    5.1   0.4     0.015        25      46      68 ..     403     425 ..     385     428 .. 0.82

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0019
      zf-UDP  10 iCqiCgddvgltedgelFvacnecafp.vcrpcyeyerk........dgnqsCPqCktr 59 
                  C+iC +d   t++   ++ +     p vc  c +   k        d    CP+C+t 
  EEA19945.1 145 SCNICVEDFSNTVTRPAWISIACAHEPsVCNICISKSIKsdletriwDQ-IRCPECQTL 202
                 6*************999987765544449999*9999888888877654.68****995 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.25
      zf-UDP  11 CqiCg.ddvgltedgelFvacnecafpvc 38 
                 Cq C   ++  +   e+ v c +c+f  c
  EEA19945.1 238 CQQCDfGQLHEKGASEPIVRCLNCGFRSC 266
                 66664234555666789999999999766 PP

  == domain 3  score: 5.1 bits;  conditional E-value: 0.015
      zf-UDP  46 rkdgnqsCPqCktrykrlkgspr 68 
                  k+ ++ CP C+   ++++g+ +
  EEA19945.1 403 MKQTTKQCPGCERPIEKNRGCDH 425
                 46899**************9975 PP

>> RR_TM4-6  Ryanodine Receptor TM 4-6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6  16.5    0.0074        12      27     135 ..     301     402 ..     278     444 .. 0.48

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0074
                 XXXXXXX...XXXXXXXXXXXXXXXXXXXXXXXX...XXXX..XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXX CS
    RR_TM4-6  27 leedlaeaageeeeedllsdvfgldlkkeggqykvvakkse..agLgDlseteaeesptpelkkklaeeeeaeeekeeeeepeaeaeekadaengekee 123
                    ++++  ++e++ +  +++ + d++ke++ +k  ++++   ag  +l+e e          ++++++ ++eee+++e+++++e+++k+d+e+     
  EEA19945.1 301 SDLEMTRRLQGEQDLEAAQEISNRDQRKEEERQKRRHREERekAGAAQLMEAER---------RRKERQRTEEEERARETKRQQEKIRKEDQERLLMDA 390
                 223455566667777778888888855555444333333220022222222222.........222233455555555555555555555555544433 PP

                 XXXX........ CS
    RR_TM4-6 124 kekekeeeekes 135
                 +++++++ + e+
  EEA19945.1 391 RRQRENALSMET 402
                 333322222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (455 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2523  (0.140722); expected 358.6 (0.02)
Passed bias filter:                      651  (0.0363099); expected 358.6 (0.02)
Passed Vit filter:                       159  (0.00886831); expected 17.9 (0.001)
Passed Fwd filter:                        37  (0.0020637); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.76u 0.31s 00:00:01.07 Elapsed: 00:00:00.45
# Mc/sec: 3054.25
//
Query:       EEA19946.1  [L=410]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (410 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       763  (0.0425568); expected 358.6 (0.02)
Passed bias filter:                      604  (0.0336884); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.42
# Mc/sec: 2940.63
//
Query:       EEA19947.1  [L=543]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.2e-09   34.8   0.0    3.7e-08   32.0   0.0    1.9  2  HSP70          Hsp70 protein
    0.00027   20.5   0.0     0.0027   17.2   0.0    2.1  2  BcrAD_BadFG    BadF/BadG/BcrA/BcrD ATPase family
  ------ inclusion threshold ------
      0.026   13.4   0.0       0.36    9.6   0.0    2.1  2  MreB_Mbl       MreB/Mbl protein
       0.12   12.0   0.0       0.44   10.2   0.0    1.7  2  Peptidase_M22  Glycoprotease family


Domain annotation for each model (and alignments):
>> HSP70  Hsp70 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.1     0.027   1.2e+02       1      16 [.      10      25 ..      10      58 .. 0.68
   2 !   32.0   0.0   8.3e-12   3.7e-08     111     370 ..      94     366 ..      50     382 .. 0.79

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.027
                EEEEEEXSSEEEEEEE CS
       HSP70  1 viGiDLGttnsvvavm 16
                v+GiD Gtt++ va  
  EEA19947.1 10 VVGIDFGTTYTGVAGP 25
                79********999844 PP

  == domain 2  score: 32.0 bits;  conditional E-value: 8.3e-12
                 HHHHHHHHHHHHHHHHHHHTSBE.EEEEEEEXTTXXHHHHHHHHHHHHHTTXEE...EEEEEHHHHHHHH..HHTCCSS..SCEEEEEEEEXSSXEEEE CS
       HSP70 111 eqisamvLkklketaeaylgkkv.tdavitvPaYfndaqRqatkdAgkiAGLnv...lRivNepTAaala..YGldkkd..kernvlvyDlGggtfdvS 201
                  ++   vL  l ++  a++ +++  + ++tvPa + +a ++ t  A + AGL++   + +v ep Aaa+    Gld +        ++ D Gggt d  
  EEA19947.1  94 AEVYNHVLYTLEQKIGAVILRTIpVEFCLTVPAIWSEAAKEKTLKACQKAGLKSaseILLVSEPEAAAIFalHGLDPHGltVGDSFVICDAGGGTVDLI 192
                 4677788888888888888777645899************************983224689*******94348999988887788999*********99 PP

                 EEEEET..TEEEEEE.EEEETTXSHHHH.HHHHHHHHHHHHHHHHSXXGGGSHHHHHHHHHHHHHHHHHTTTSSCSEEEEEEEEEETTT....EEEEEE CS
       HSP70 202 ilelek..Gvfevka.TagDthlGGedf.DealvehlveefkkkegidlskdkkalqrlkeaaekaKkeLSsskqteinleietvdedg....kdlsek 292
                   ++++   +++v   Tag   l G  f  ++ ++++ +++ ++ g d +  ++a +r  + + k     S   +   ++++  + +d+       + +
  EEA19947.1 193 SYRIKSlyPILQVEEiTAGTGGLCGSVFlNRRFIDFIKRKLSRQPGWDDEVLSEASERFDT-VIKQQYLPSRDGDDGYPVPVPGLANDQrvgiRRGKFT 290
                 8999862269999755999999***9995678**************************965.67777888988899999***99999654223344678 PP

                 EEHHHHHHHHHHHHHHTHHHHHHHHHHCTEEGGGCSEEEEESGGGGSHHHHHHHHHHTT.CHHBSSSHTTTHHHHHHHH CS
       HSP70 293 lsRakfeelvedllertlepvekalkdaklkkeeidevvlvGGstRiPkvqelvkelfg.kepsktvnpDeavaiGAAv 370
                 ++++ ++++ e+++++++  v+  ++ ++      ++v+lvGG      ++e+++e +   e  +  n+  a+ +GA +
  EEA19947.1 291 IQKNDMHDIFEPIIHKIILFVQDQIRLSGG---KAKSVLLVGGFGQNTYLKERLRESLPnIEVLQPPNAWTAIVRGAVM 366
                 899999999999999999999988775555...556899****999999999888876546777777777777777766 PP

>> BcrAD_BadFG  BadF/BadG/BcrA/BcrD ATPase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.0      0.05   2.2e+02       1      54 [.      11      99 ..      11     219 .. 0.70
   2 !   17.2   0.0   6.1e-07    0.0027     192     266 ..     297     367 ..     292     368 .. 0.87

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.05
                 EEEEE-SSEEEEEEEETTTEEEEEEEE--.....................................TTS-HHH.........HHHHHHHHH CS
  BcrAD_BadFG  1 vGiDgGsTttkavlmdekgevlgrgitns.....................................anlesvrfeaaekvleealtealer 54
                 vGiD G+T t ++    + +vlg     s                                     +n++ v+++ ae+   + l e+ + 
   EEA19947.1 11 VGIDFGTTYTGVA--GPRRDVLGSNEGESsvkvptqlrytpqgtewgfqipstvernhwfklglqeNNTSDVGQKSAEGLTTDYLAEVYNH 99
                 89***99988644..4444577777766667777777777777777777777777777777777766666677777666666666666555 PP

  == domain 2  score: 17.2 bits;  conditional E-value: 6.1e-07
                  HHHHHHHHHHHHHHHHHHHHTT---SS.EEEESGGGG-HHHHHHH.....HHHH-S-EE--GGGGGHHHHHHHHH CS
  BcrAD_BadFG 192 edIlaglhraialrvialisrsggvtdevtltGGvakneaavkelrklvkenygevkininpdsiytgalGAalf 266
                   dI++ + ++i+l v  +i+ sgg  + v+l+GG+ +n      l++ + e+  + ++ ++p +  + + GA+++
   EEA19947.1 297 HDIFEPIIHKIILFVQDQIRLSGGKAKSVLLVGGFGQN----TYLKERLRESLPNIEVLQPPNAWTAIVRGAVMM 367
                  69************************************....445566788888888889999999999999987 PP

>> MreB_Mbl  MreB/Mbl protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.0   8.1e-05      0.36      96     159 ..     120     191 ..      88     233 .. 0.79
   2 ?    1.3   0.0     0.026   1.2e+02     273     318 ..     321     367 ..     276     375 .. 0.75

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 8.1e-05
                 EEEEE-SS--HHHHHHHHHHHHHTT...-SEEEEEEHHHHHHHHT..T--...TTSSS-EEEEEE-SS-EEE CS
    MreB_Mbl  96 vvicvPsgiteverrAvkeaakkaG...arevllieeplaAAiGa..glp...veepsgnmvvdiGggttev 159
                   ++vP   +e  ++   +a++kaG   a+e+ll++ep aAAi a  gl+   ++   + +++d Gggt ++
  EEA19947.1 120 FCLTVPAIWSEAAKEKTLKACQKAGlksASEILLVSEPEAAAIFAlhGLDphgLTVGDSFVICDAGGGTVDL 191
                 5677888889999999999999999777899************88555552223444567899******885 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.026
                 HHH-EEEESGGGGSBTHHHHHHHHH.SS-EEE-SSTTTHHHHHHHHT CS
    MreB_Mbl 273 vdrgivltGGgallkgldkllseet.glpvkvaedpltcvakGtgkv 318
                   ++++l+GG ++   l++ l+e++ +++v    ++ t++++G+ ++
  EEA19947.1 321 KAKSVLLVGGFGQNTYLKERLRESLpNIEVLQPPNAWTAIVRGAVMM 367
                 458899***************9997689***************9876 PP

>> Peptidase_M22  Glycoprotease family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0      0.34   1.5e+03     180     227 ..      84     151 ..      28     161 .. 0.62
   2 ?   10.2   0.0   9.9e-05      0.44     221     259 ..     317     355 ..     271     359 .. 0.79

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.34
                    E.CHHHHHHHHHH.ST.T...............HHHHHHHHHHHHHHHHHHHHHHHHHH...CTBSEE CS
  Peptidase_M22 180 sfsGlktavlkel.ek.e...............vedlaasfqeavvdhlvekteralkl...pkakel 227
                    s  Gl t+ l e+ ++                   +++  + +   + + ekt +a+++   ++a+e+
     EEA19947.1  84 SAEGLTTDYLAEVyNHvLytleqkigavilrtiPVEFCLTVPAIWSEAAKEKTLKACQKaglKSASEI 151
                    44444444444443222134445556666666666777777777777777777777777444444444 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 9.9e-05
                    H..CTBSEEEEESGGGGXHHHHHCHCCHHHHTTSEEEXXXH CS
  Peptidase_M22 221 l..pkakelvilGGvaankrLrealeeeaeelglkliiPpl 259
                    l   kak+++++GG+++n +L+e+l+e  + ++++++ Pp+
     EEA19947.1 317 LsgGKAKSVLLVGGFGQNTYLKERLRE--SLPNIEVLQPPN 355
                    355799*******************84..447899999985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (543 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       425  (0.0237046); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3690.53
//
Query:       EEA19948.1  [L=352]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      0.002   18.4   0.0     0.0028   18.0   0.0    1.4  1  PhyH      Phytanoyl-CoA dioxygenase (PhyH)
  ------ inclusion threshold ------
      0.049   12.4   0.0       0.43    9.3   0.0    2.3  2  DUF1479   Protein of unknown function (DUF1479)


Domain annotation for each model (and alignments):
>> PhyH  Phytanoyl-CoA dioxygenase (PhyH)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   3.1e-07    0.0028     121     209 ..     173     272 ..      71     274 .. 0.79

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 3.1e-07
                 GCCEEEEEEESS-B-TTBT-EEEETTGGGS-CCGTCCHHCSGCCTTS.............CCCTTTGHGSCEEEE.BTTTEEEEEETTSEEEE-TB.SS CS
        PhyH 121 eesvvgvwialedateenGclrfiPGSHkweegplrrrlpeddteae.............ddeakkedeeeavpvevkaGdavlfhgrllHgsgaNrsd 206
                 e ++v+  + l +  ++ G+l +  GS     + + ++  ++ + ++               ++ +++  ++v v  ++Gd++l+++r++H ++  +s+
  EEA19948.1 173 EFNCVQGILNLLPNGPQDGGLTVFEGSSAL--YTELWKHFDHKKGETgwnpqafqfiddeMSQWLESKGCKWVKVCAQPGDLLLWDSRCIHYGAVPSST 269
                 566777777777777888888888888766..333344444444444667777799976545555666679********************98766666 PP

                 SXE CS
        PhyH 207 ksR 209
                   R
  EEA19948.1 270 NDR 272
                 655 PP

>> DUF1479  Protein of unknown function (DUF1479)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.0     0.031   2.7e+02      64     102 ..      39      77 ..       3      95 .. 0.74
   2 ?    9.3   0.0   4.8e-05      0.43     324     381 ..     247     303 ..     165     310 .. 0.89

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 0.031
                 -HHHHHHHHHHTEEEEETSS-HHHHHHHHHHHHHHHHHT CS
     DUF1479  64 saefsaeikrrGvlvvrgvvpeeeaeewkeeikeYlekn 102
                 + + + e++++G  vv + +p+e+a  + e+  ++le+ 
  EEA19948.1  39 TPNWLVELHTKGWTVVPQTIPRERALIYAEKAYRWLESW 77 
                 46667789999*************999999999988865 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 4.8e-05
                 B-TT-EEEEETT--EEE-SBCSSSS-EEEEE--B-EESHHHHHHHHHHHHHHHHT--- CS
     DUF1479 324 leaGDyvvWhcdlihavdkehegkkdssvlYipavPltqknaeylarqrkaflrgkpp 381
                  ++GD ++W + +ih    ++++++d+   Yi   P ++  ae  +r  +af +g++ 
  EEA19948.1 247 AQPGDLLLWDSRCIHY-GAVPSSTNDRFAAYICYKPASNVSAEDKKRRLEAFKNGQST 303
                 589************7.5678889999999************************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (352 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       270  (0.0150594); expected 358.6 (0.02)
Passed bias filter:                      255  (0.0142228); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2563.95
//
Query:       EEA19949.1  [L=478]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    6.3e-13   48.5   0.0    1.9e-12   46.9   0.0    1.8  1  PNP_UDP_1  Phosphorylase superfamily


Domain annotation for each model (and alignments):
>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.9   0.0   1.1e-16   1.9e-12       1     181 [.      53     338 ..      53     374 .. 0.87

  Alignments for each domain:
  == domain 1  score: 46.9 bits;  conditional E-value: 1.1e-16
                 CEEEEESSHHHHHHHHHH.....EEEEEEEEEE..TTEEEEEEEETTEEEEEEE--.SSHHHHHHHHHHHHHHHC--SEEEEEEEEEES.....STTT- CS
   PNP_UDP_1   1 kiaiivgspgevellaes.....pleetpfgre.grgfkfvtGtlkgkpvvivstG.iGkpnaavvaeirllkefgvkaiiriGtaGgl.....npdlk 87 
                 +iaii++ p e++++ +        +  p+g++ g + +++tG +++++vv+v +  +Gk+na  va+   +   ++k  + +G++G       ++++ 
  EEA19949.1  53 EIAIICALPLEYDAVVDAfdgfwNDDGDPYGKVvGDQNTYTTGWIGQHNVVLVVCSdVGKVNATSVATSCSMSFTQIKLAFLVGICGVAprttdRNEIL 151
                 59*******************9989999999999***********999998887777*******888888888779*************8988878899 PP

                 TT-EEEEEEEEESSSCCGCCTHHCC.................................................................TCCCCTTSS CS
   PNP_UDP_1  88 vGDvvipddainfdgrsplygpkee.................................................................gqyfpdsyd 121
                 +GDv+i d+++ +d++ ++  +                                                                     + +  ++ 
  EEA19949.1 152 LGDVIIGDQIVAYDFGKRYADELKLkssltfkttdkshsvrrfmntmqtdhyrelllrratdhlqtvrdrysskygspqrsedrlftpeyRHKHHKPRT 250
                 ************9999996655555999***********************************************999999999999888666666666 PP

                 EE--HHHHHHHHH........CHHTTT....................TTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHH CS
   PNP_UDP_1 122 apadpelrallke........aaealg....................ikvhrGvvatadgfyaeteaelrllrrlgadaveMEtaava 181
                  p + e++++ k          +e+lg                    + +h Gv+a+ad++  + ++++ + +++g+ a eME+   +
  EEA19949.1 251 CPICDECTTTSKSvcevalasICEDLGcdsdqliprqrlangdvpqsPVLHWGVFASADTVLKSARDRDWIAEKYGVIAFEMEATGAC 338
                 6677777777777887777664444447778888888888999****************************************87655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (478 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       857  (0.0477997); expected 358.6 (0.02)
Passed bias filter:                      601  (0.0335211); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3235.43
//
Query:       EEA19950.1  [L=503]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
     0.0082   16.4   0.0        1.2    9.5   0.0    2.5  2  AAA_22        AAA domain
  ------ inclusion threshold ------
      0.017   15.5   0.0        1.3    9.3   0.0    2.3  2  AAA_16        AAA ATPase domain
      0.044   13.1   0.0      0.081   12.2   0.0    1.3  1  Zeta_toxin    Zeta toxin
       0.05   13.7   0.0         11    6.0   0.0    2.2  2  DUF87         Helicase HerA, central domain
       0.08   12.3   0.0       0.14   11.5   0.0    1.3  1  FtsK_SpoIIIE  FtsK/SpoIIIE family


Domain annotation for each model (and alignments):
>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.5   0.0   0.00032       1.2       6      28 ..      91     113 ..      87     184 .. 0.86
   2 ?    4.4   0.0     0.011        41      91     130 ..     331     377 ..     292     380 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00032
      AAA_22   6 gilvvtGesGtGKTtllrrlleq 28 
                  +++++G  G+GK+++l  +le+
  EEA19950.1  91 LSTFICGSQGSGKSHTLSCVLES 113
                 5789************9998876 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.011
      AAA_22  91 v..ielliiDEaqh.lr....seealeeLrsllnlsrkgvqliLvGt 130
                 +   +++ +DEa++ l     s++   +L s + l+r++ + iL+ t
  EEA19950.1 331 TdvGRVVALDEAHKyLKgsidSQNFTDTLLSTVRLQRHLGARILIST 377
                 344579********997855548888888888777788888888766 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.0   0.00037       1.3      22      48 ..      88     114 ..      84     140 .. 0.84
   2 ?    3.9   0.0     0.017        61      91     164 ..     251     365 ..     203     375 .. 0.69

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00037
      AAA_16  22 grpelvllsGesGvGKsslvrellral 48 
                  +p ++++ G +G+GKs  + ++l++ 
  EEA19950.1  88 TSPLSTFICGSQGSGKSHTLSCVLESC 114
                 578999*****************9865 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.017
      AAA_16  91 saeleawrekleeala.......................................avpelagaeasrllellkrllallsrderplvlvlDdlqwade. 149
                  ++le+ +++le+  +                                       ++p ++++ a +l++++ ++++   + +   v+ lD++++    
  EEA19950.1 251 PSQLEPLKQRLETLESfmphqqvrlaqnskkskgkaqmkgsswtpkpsqltivdlSCPCITPDTACSLFNVCFEIFMEQNT-DVGRVVALDEAHKYLKg 348
                 34555555555554446666666666666777777778888889999999899999999999999***********66666.4448********65554 PP

      AAA_16 150 ..aslqllaaLlrlles 164
                   +s+++ ++Ll+++  
  EEA19950.1 349 siDSQNFTDTLLSTVRL 365
                 44777777777766555 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   2.3e-05     0.081      14      39 ..      88     113 ..      76     124 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2.3e-05
  Zeta_toxin  14 erPklillgGqpGAGKselaellkde 39 
                  +P + ++ G++G+GKs++++ + ++
  EEA19950.1  88 TSPLSTFICGSQGSGKSHTLSCVLES 113
                 6899****************998876 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.0    0.0031        11      28      50 ..      95     117 ..      86     136 .. 0.84
   2 ?    5.4   0.0    0.0049        17      86     209 ..     181     306 ..     148     317 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.0031
       DUF87  28 ilgsTGsGKSntvavLleellek 50 
                 i gs GsGKS+t +  le+ l +
  EEA19950.1  95 ICGSQGSGKSHTLSCVLESCLLS 117
                 78999*********999998764 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.0049
       DUF87  86 kdkelkinpwsldpeelldlleeddkpaaav..qrsvleealdqakakeekeklssdepveklleelkkekeelrklknqaiarlldkledllrkggsf 182
                   ++l+i+ +sl+ + +ldl+ + ++++ ++      ++++l++++   ++++++s    + ++++l    ++l  ++ +  ++ l++le+++ +++ +
  EEA19950.1 181 HVEPLQIDQSSLNTKRMLDLMAV-GQEKGPIplYMHTVQRILREMR--LLQQETDSGFDYYMFKKKLL--GADLLPSQLEPLKQRLETLESFMPHQQVR 274
                 56789999999999999999999.4444344335667899999999..99999999888888888998..44444445555556668999999999999 PP

       DUF87 183 .....snsstdliallleklekegkitiidls 209
                      ++s+ +   +   +  k++++ti+dls
  EEA19950.1 275 laqnsKKSKGKAQMKGSSWTPKPSQLTIVDLS 306
                 988765666666777788999*********98 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   3.8e-05      0.14      27      70 ..      78     121 ..      65     124 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 3.8e-05
                   TS-EEEEEGGGS-.SEEEE--TTSSHHHHHHHHHHHHHTT--TT CS
  FtsK_SpoIIIE  27 sgnplvldlkkmashllvaGatgsGKStalntLilSlatthtPe 70 
                    ++p v+  ++++  + ++G++gsGKS +l   + S ++ +++ 
    EEA19950.1  78 KNDPRVFLNITSPLSTFICGSQGSGKSHTLSCVLESCLLSSNAG 121
                   67777777778888899*************99999988877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (503 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       509  (0.0283898); expected 358.6 (0.02)
Passed bias filter:                      476  (0.0265492); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.43
# Mc/sec: 3509.74
//
Query:       EEA19951.1  [L=217]
Description: hypothetical protein PMAA_007170 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00054   20.6   0.0    0.00092   19.9   0.0    1.5  1  dsrm      Double-stranded RNA binding motif


Domain annotation for each model (and alignments):
>> dsrm  Double-stranded RNA binding motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   0.0   5.1e-08   0.00092      31      67 .]     178     213 ..     153     213 .. 0.87

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 5.1e-08
                 EEEEEEEEETTEEEEEEEESSHHHHHHHHHHHHHHHH CS
        dsrm  31 pkFvvtvkvngklygsGvgsnKKeAeqsAAedalekL 67 
                 p+ ++t+ ++  +  +G+g++KK A ++AA++++ kL
  EEA19951.1 178 PRMKATISFGALEA-TGIGRTKKIAGHLAAKEICDKL 213
                 56678888866666.*******************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (217 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       230  (0.0128284); expected 358.6 (0.02)
Passed bias filter:                      224  (0.0124937); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.43
# Mc/sec: 1522.51
//
Query:       EEA19952.1  [L=517]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.7e-20   71.7   3.7      1e-19   70.3   3.7    1.8  1  OTT_1508_deam  OTT_1508-like deaminase


Domain annotation for each model (and alignments):
>> OTT_1508_deam  OTT_1508-like deaminase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.3   3.7   5.7e-24     1e-19       1      63 [.     355     416 ..     355     417 .. 0.92

  Alignments for each domain:
  == domain 1  score: 70.3 bits;  conditional E-value: 5.7e-24
  OTT_1508_deam   1 vHAEvqlleyleeekdkekqepryIgcSKpaCylCelylrahgkatlkvreshgklydkWrlP 63 
                    vHAE+q++e++ +++ +   ++r+I+cSKpaC++Cely+++h+ a+++v++sh k++ +W++P
     EEA19952.1 355 VHAEIQVMEHFCQSQLAFAFNDRFIACSKPACLCCELYFKHHP-ARIVVPSSHRKVWTNWSPP 416
                    8************8866555599*******************9.9999**************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (517 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       800  (0.0446204); expected 358.6 (0.02)
Passed bias filter:                      601  (0.0335211); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.41
# Mc/sec: 3807.50
//
Query:       EEA19953.1  [L=47]
Description: hypothetical protein PMAA_007190 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (47 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       273  (0.0152267); expected 358.6 (0.02)
Passed bias filter:                      206  (0.0114898); expected 358.6 (0.02)
Passed Vit filter:                         5  (0.000278878); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.27s 00:00:00.69 Elapsed: 00:00:00.46
# Mc/sec: 304.52
//
Query:       EEA19954.1  [L=402]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
  ------ inclusion threshold ------
      0.022   14.8   3.7      0.052   13.5   3.7    1.6  1  TMF_DNA_bd  TATA element modulatory factor 1 DNA binding


Domain annotation for each model (and alignments):
>> TMF_DNA_bd  TATA element modulatory factor 1 DNA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   3.7   2.9e-06     0.052       3      47 ..      29      73 ..      28      77 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.9e-06
  TMF_DNA_bd  3 lekklkeKDeqIaqLmeEGekLskkelklnntikkLrkknkelek 47
                l k+++eK++q+ +L +E+e  +++ l+   ++ +L+++nk l+ 
  EEA19954.1 29 LIKTIDEKEDQVRKLNYELEHERDSRLRYQHKVRELQEDNKTLDG 73
                5799*************************************9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (402 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       938  (0.0523175); expected 358.6 (0.02)
Passed bias filter:                      636  (0.0354733); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.30s 00:00:00.89 Elapsed: 00:00:00.49
# Mc/sec: 2474.07
//
Query:       EEA19955.1  [L=56]
Description: hypothetical protein PMAA_007210 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (56 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       207  (0.0115455); expected 358.6 (0.02)
Passed bias filter:                      162  (0.00903564); expected 358.6 (0.02)
Passed Vit filter:                         8  (0.000446204); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.35u 0.25s 00:00:00.60 Elapsed: 00:00:00.41
# Mc/sec: 412.51
//
Query:       EEA19956.1  [L=232]
Description: recombination hotspot-binding protein (Translin), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.3e-51  173.5   0.1    6.6e-51  173.2   0.1    1.0  1  Translin    Translin family
  ------ inclusion threshold ------
      0.098   12.7   0.0       0.57   10.3   0.0    2.0  2  GMP_synt_C  GMP synthase C terminal domain


Domain annotation for each model (and alignments):
>> Translin  Translin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  173.2   0.1   7.3e-55   6.6e-51       3     205 .]      21     227 ..      20     227 .. 0.87

  Alignments for each domain:
  == domain 1  score: 173.2 bits;  conditional E-value: 7.3e-55
                 HHHHHHHHHHHHHHHHHHHHHHHTTGSST.TT....HHHHHHH.H....HHHHHHHHHHTTSS..........GHHHHGGGTH.HHHHHHHHHHHHHHH CS
    Translin   3 reriikasrditaaskkiifllhrvrsek.te....aqdkkakik....keakeklkeiakllasvaeelqgsnayrYqrqisgglqeliealsfahYl 92 
                 r+++ ++++ + ++ ++++++l+r++s++ +        ++a+++    ke  +          ++ae  +++++y+Y+  +s++lq+l+  + ++ +l
  EEA19956.1  21 RDELHEIVQSLARKGRTTQAILSRAHSTPsKDikpvL--DDAATQilaqKEDVS----------RLAEIANKHPFYKYNGVWSRELQNLVYYIELCAWL 107
                 9*************************99944454221..222222212333333..........444444556************************** PP

                 H..........HSS---HHHHHHHTT.---S..SSSSS---HHHHHHHHHHHHHHHHHHHHHHHCTT--S.HHHHHHHHHHHHHHHHHTS----HH... CS
    Translin  93 e..........tqtLitleevqkilealken..eedafhltpedYllGlfdLtgELmRfainsvalgdkeekplqilkflrelragfellnlkndsakd 179
                 +          +++++t+eev++ l  +++n  +ed+fhlt+e+Yll+l+++++EL+R+a+nsv+lgd++ +pl+i +f+++l+agf+llnlknd+   
  EEA19956.1 108 GglteyknsssKTSFLTIEEVGNFLD-IPVNlkDEDKFHLTIEEYLLSLISMVEELSRLAVNSVTLGDYH-RPLEINNFIKDLFAGFQLLNLKNDI--- 201
                 *********99999***********9.678888************************************9.************************9... PP

                 HHHHHTTHHHHHHHHHHHHHHHHHHT CS
    Translin 180 lrkKldvlkqsvkKvEdvvYdlsvRg 205
                 lrk+ d++k+svkKvEdvvYdls+R+
  EEA19956.1 202 LRKRSDGIKYSVKKVEDVVYDLSLRN 227
                 ************************96 PP

>> GMP_synt_C  GMP synthase C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.15   1.3e+03      59      85 ..      55      80 ..      32      83 .. 0.79
   2 ?   10.3   0.0   6.3e-05      0.57      53      83 ..     194     224 ..     184     228 .. 0.90

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.15
                HHHHHHHHHHHHHSTT---EEEE---T CS
  GMP_synt_C 59 evLekissrivnevkgvnrvvyditsk 85
                 vL++ +++i+ + ++v+r+  +i++k
  EEA19956.1 55 PVLDDAATQILAQKEDVSRLA-EIANK 80
                478899999999999999974.55555 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 6.3e-05
                 B----HHHHHHHHHHHHHHSTT---EEEE-- CS
  GMP_synt_C  53 vaelpyevLekissrivnevkgvnrvvydit 83 
                 + +l+ ++L+k s+ i  +vk+v  vvyd++
  EEA19956.1 194 LLNLKNDILRKRSDGIKYSVKKVEDVVYDLS 224
                 568999***********************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (232 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       669  (0.0373138); expected 358.6 (0.02)
Passed bias filter:                      520  (0.0290033); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.30s 00:00:00.76 Elapsed: 00:00:00.50
# Mc/sec: 1400.07
//
Query:       EEA19957.1  [L=197]
Description: glutathione peroxidase Hyr1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.7e-39  132.3   0.0    7.1e-39  131.7   0.0    1.3  1  GSHPx     Glutathione peroxidase
    0.00047   20.1   0.0    0.00093   19.1   0.0    1.5  1  AhpC-TSA  AhpC/TSA family
  ------ inclusion threshold ------
      0.086   12.5   0.1       0.14   11.8   0.0    1.5  2  Redoxin   Redoxin


Domain annotation for each model (and alignments):
>> GSHPx  Glutathione peroxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  131.7   0.0   1.2e-42   7.1e-39       1     108 []       7     117 ..       7     117 .. 0.95

  Alignments for each domain:
  == domain 1  score: 131.7 bits;  conditional E-value: 1.2e-42
                 GGGBEEEBTTSSEEEGGGGTTSEEEEEEEESSSTTHHHHHHHHHHHHHHGGG...TEEEEEEEE-TTTT---S-GGGHHHTSSHTTT-SSEEB--BBSS CS
       GSHPx   1 iyelsakdidgekvkleklrgkvvlivnvaskCglteqykeleelqkrykdk...glvilgfPCnqfgkqepgsdeeikkfrqgkyevtfellekievn 96 
                 +y++s+ d++g++ +l  ++gkvvl+vn askCg+t+q+  le+l+k  + k    ++ilgfPCnqfg+q+pgs++ei+ f+q +y+vtf++l ki+vn
  EEA19957.1   7 FYDFSPPDKKGNPYPLTDYKGKVVLVVNTASKCGFTPQFAGLEKLYKSIEAKhpgAFTILGFPCNQFGNQDPGSNDEIQSFCQVNYGVTFPVLGKIDVN 105
                 7*********************************************9987553337******************************************* PP

                 STTB-HHHHHHH CS
       GSHPx  97 Gekedplykflk 108
                 G+k++pl++++k
  EEA19957.1 106 GSKAEPLFEWIK 117
                 **********97 PP

>> AhpC-TSA  AhpC/TSA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   1.6e-07   0.00093       5      58 ..       7      58 ..       4     106 .. 0.77

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 1.6e-07
                ----EEESTTCEEEECHHHTTSEEEEEEESTST-CCHHHHHHHHHHCHHHCCCT CS
    AhpC-TSA  5 apdfelknadgetvslsdykgkpvvlffypkdwcpvCttelpalaklyeefker 58
                + df+ ++++g+++ l+dykgk+v+++ +++  c ++  +   l+kly+ ++++
  EEA19957.1  7 FYDFSPPDKKGNPYPLTDYKGKVVLVVNTAS-KCGFT-PQFAGLEKLYKSIEAK 58
                569******************6666666666.88876.78999****9999977 PP

>> Redoxin  Redoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   2.4e-05      0.14       6      54 ..       7      51 ..       2      98 .. 0.81
   2 ?   -3.0   0.0      0.89   5.3e+03      59      65 ..     171     177 ..     136     191 .. 0.52

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 2.4e-05
                B---ECCEETTCEEEEEHHHHTTSEEEEEEESTTT-HHHHHTHHHHHTH CS
     Redoxin  6 aPdftlplaatdgnsvslsefkgkkvvvnfvpgafcPtCsaehpylekl 54
                + df+ p+  ++gn++ l ++kgk+v+v+  ++  c+  +++   lekl
  EEA19957.1  7 FYDFSPPD--KKGNPYPLTDYKGKVVLVVNTAS-KCGF-TPQFAGLEKL 51
                55788777..9****************999999.8875.4444455555 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.89
                 HCSTTTE CS
     Redoxin  59 kekgvdv 65 
                   kgv+v
  EEA19957.1 171 DVKGVEV 177
                 3344444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (197 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       352  (0.019633); expected 358.6 (0.02)
Passed bias filter:                      316  (0.0176251); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.41u 0.23s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1484.72
//
Query:       EEA19958.1  [L=113]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-30  105.0   0.2    2.1e-30  104.7   0.2    1.1  1  Pcc1      Transcription factor Pcc1


Domain annotation for each model (and alignments):
>> Pcc1  Transcription factor Pcc1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.7   0.2   1.1e-34   2.1e-30       1      74 []      14     100 ..      14     100 .. 0.91

  Alignments for each domain:
  == domain 1  score: 104.7 bits;  conditional E-value: 1.1e-34
                 EEEEEEE-SSHHHHHHHHHHHHHHCHC-TTECEEEEEEETT..............EEEEEEEESSHHHHHHHHHHHHHHHHHHHHHHH CS
        Pcc1   1 sltisvpfpterlAsialrtLqvDkelsplavkrslslegn..............vLqveykAttnrmLRvavngfleslglvletme 74 
                 sl is+p+pt+rlAs+al+++qvD+elspl v+r++ l  +              vL+++y+AttnrmLRv+vngf++ lg+vl+++e
  EEA19958.1  14 SLVISIPLPTNRLASAALQAIQVDQELSPL-VRRDFALISPnpdanddadeasktVLETTYRATTNRMLRVSVNGFMDTLGVVLGVIE 100
                 689***************************.*******55556666666667777*******************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (113 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       318  (0.0177366); expected 358.6 (0.02)
Passed bias filter:                      283  (0.0157845); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.24s 00:00:00.62 Elapsed: 00:00:00.41
# Mc/sec: 833.65
//
Query:       EEA19959.1  [L=605]
Description: protein-tyrosine phosphatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.1e-43  146.9   0.0    1.7e-40  138.7   0.0    2.5  2  DSPn            Dual specificity protein phosphatase, N-termi
    6.2e-16   58.4   0.1    1.6e-15   57.1   0.0    1.7  2  DSPc            Dual specificity phosphatase, catalytic domai
    3.4e-06   26.8   0.0    5.9e-06   26.0   0.0    1.3  1  Y_phosphatase   Protein-tyrosine phosphatase
  ------ inclusion threshold ------
       0.17   11.5   0.0       0.33   10.5   0.0    1.4  1  Y_phosphatase2  Tyrosine phosphatase family


Domain annotation for each model (and alignments):
>> DSPn  Dual specificity protein phosphatase, N-terminal half
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.7   0.0   3.7e-44   1.7e-40       2     141 .]      15     182 ..      14     182 .. 0.89
   2 !    5.5   0.0    0.0049        22      67     107 ..     323     360 ..     302     368 .. 0.70

  Alignments for each domain:
  == domain 1  score: 138.7 bits;  conditional E-value: 3.7e-44
        DSPn   2 iikdrLyfatlkkkpketen.............................vhyfsiddelvYenFyaDFGPlnlaqlyrfcvkvnkkLkskelskkkivh 71 
                  i+drLy+a+++++p+  +                               +yf++dd+l Y+ F+aDFGPl++++lyrf+v+ +++L ++++++k +v+
  EEA19959.1  15 YIQDRLYLASYSSTPDPYAAfpfptqasspskrsakasqspvraakhkfPVYFTVDDTLLYNAFHADFGPLHIGHLYRFAVHFHEILGDPANAEKPVVF 113
                 688999999877544443333445556667777778888888999888899************************************************ PP

        DSPn  72 ytsadekkranaafLigaYavivlklspeealkplasqekppllpFrDaslgectyeltlldclkglekA 141
                 y++ d+++ranaa+L+++Y+v+++++ p+ al+p+a++ +pp++pFrDa+++++++ l+++d+++g++kA
  EEA19959.1 114 YSKPDPRSRANAACLVACYMVLIQSWPPHLALAPIAQA-DPPYMPFRDAGYSQADFILNIQDVVYGVWKA 182
                 *************************************6.9*****************************8 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.0049
        DSPn  67 kkivhytsadekkranaafLigaYavivlklspeealkpla 107
                 k+i ++++a      ++ +LigaY++  ++++++e+++ ++
  EEA19959.1 323 KNIAVHCKA---GLGRTGCLIGAYLIYRHGFTANEIIAFMR 360
                 444444444...3456789****************998776 PP

>> DSPc  Dual specificity phosphatase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.1       1.7   7.6e+03      88      98 ..     126     136 ..     123     144 .. 0.81
   2 !   57.1   0.0   3.6e-19   1.6e-15      34     127 ..     278     375 ..     258     380 .. 0.83

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 1.7
                 HHHHHHHHHHH CS
        DSPc  88 atliiaYlmkt 98 
                 a+l+++Y+   
  EEA19959.1 126 ACLVACYMVLI 136
                 99*****9765 PP

  == domain 2  score: 57.1 bits;  conditional E-value: 3.6e-19
                 CCTTTTSEEEEEC.CESSTTSCCGGGHHHHHHHHHHH....HHTT-EEEEEESSSSSHHHHHHHHHHHHHHTSCHHHHHHHHHHHSTT-SSTHHHHHHH CS
        DSPc  34 alkkseieklrip.vedehetkiskyleeavefidka....kqkgkkvlVHCqaGisRSatliiaYlmktknlslneayeflkerrpaispnagfirqL 127
                 +++ s ++ l i  ++   e+ +++ l+ + +fi+ a    + ++k+++VHC+aG+ R+++li aYl++++++++ne + f++  rp ++    ++++L
  EEA19959.1 278 LYCPSYFTALGINhIDMIFEDGTCPPLPLVRRFIKMAhemiAVQKKNIAVHCKAGLGRTGCLIGAYLIYRHGFTANEIIAFMRFMRPGMVVG-PQQHWL 375
                 4556677778888666689999999999999***9885666679******************************************999887.555555 PP

>> Y_phosphatase  Protein-tyrosine phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0   0.0   1.3e-09   5.9e-06     157     225 ..     309     372 ..     297     377 .. 0.82

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 1.3e-09
                    HHHHHHHHHHSTTSS-EEEECSSSSHHHHHHHHHHHHHHHHHHHSEEEHHHHHHHHHTTSTTSS-SHHH CS
  Y_phosphatase 157 klirkvekskeaksgpvvVhCsaGvgRtgtfvaldillqqleaeeevdvlqivkelrkqRpgmvqtleq 225
                    ++i+++++    +++ + VhC+aG gRtg+++ + +++++  +       +i+  +r +Rpgmv   +q
     EEA19959.1 309 RFIKMAHEMIAVQKKNIAVHCKAGLGRTGCLIGAYLIYRHGFT-----ANEIIAFMRFMRPGMVVGPQQ 372
                    67777777778889*******************9998876555.....788999999999999977766 PP

>> Y_phosphatase2  Tyrosine phosphatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   7.3e-05      0.33      71     111 ..     303     342 ..     274     368 .. 0.73

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 7.3e-05
                     G----HHHHHHHHHHHH-GGG-SEEEE-SSSSSHHHHHHHH CS
  Y_phosphatase2  71 lveiksdllkkalklllnkenypvllhckrGkhrtglvigc 111
                       +++   +k+a + ++ +++ ++ +hck G  rtg++ig+
      EEA19959.1 303 PLPLVRRFIKMAHE-MIAVQKKNIAVHCKAGLGRTGCLIGA 342
                     55555555555544.5678889*****************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (605 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       602  (0.0335769); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.58u 0.26s 00:00:00.84 Elapsed: 00:00:00.43
# Mc/sec: 4214.94
//
Query:       EEA19960.1  [L=88]
Description: hypothetical protein PMAA_007270 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (88 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       559  (0.0311785); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.37u 0.26s 00:00:00.63 Elapsed: 00:00:00.41
# Mc/sec: 642.47
//
Query:       EEA19961.1  [L=894]
Description: alpha-glucosidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   3.3e-146  487.9   8.1   4.6e-146  487.5   8.1    1.2  1  Glyco_hydro_31   Glycosyl hydrolases family 31
    1.2e-37  128.7   0.1      2e-37  127.9   0.1    1.4  1  NtCtMGAM_N       N-terminal barrel of NtMGAM and CtMGAM, malt
    1.2e-10   41.6   0.4    5.1e-10   39.5   0.4    2.2  1  Gal_mutarotas_2  Galactose mutarotase-like
  ------ inclusion threshold ------
        0.1   12.4   0.0       0.23   11.2   0.0    1.5  1  AMP_N            Aminopeptidase P, N-terminal domain


Domain annotation for each model (and alignments):
>> Glyco_hydro_31  Glycosyl hydrolases family 31
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  487.5   8.1    1e-149  4.6e-146       1     440 []     243     770 ..     243     770 .. 0.94

  Alignments for each domain:
  == domain 1  score: 487.5 bits;  conditional E-value: 1e-149
                     EEEE-SSHHHHHHHHHHHH-------GGGGSEEEE-TT--SHHHHHHHHHHHHHTT--EEEEEESCGGSBTTCCTB-.TTTSS..-HHHHHHHHH CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxx RF
  Glyco_hydro_31   1 yvflGptpkevvkqyteltGrpalpPrwalGfhqsrygykdeeeveevvdkfreagiPldvivlDidymdkrkdftwdkerFp..dpkemvdelh 93 
                     y+++Gp p++v++qy+ ++G+pa + +w++Gfhq++ygy+d  +v+ev+ ++++a+iPl+++++Didymd r+++++d++rFp  + +e+v++lh
      EEA19961.1 243 YFLSGPAPADVARQYAGVVGTPAQQSYWTYGFHQCKYGYQDVMWVAEVAYNYSQANIPLETMWTDIDYMDLRRTWNLDPDRFPlhKMQELVAYLH 337
                     9**********************************************************************************9555******** PP

                     HTT-EEEEEE-SEE.E.-TTSHHHHHHHHTTSBECCCCCS.TCEC.TSSEEEEB-TTSHHHHHHHHHHHHHHHCT...CT--EEEE-STTTB.SC CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxx RF
  Glyco_hydro_31  94 ekgvklvvivdpaiskqeeeyeafdegkekgvflknkdgs.ykgk.wpgstafpDftnpearewwkkelkkflld...lgvdglwiDmnepsnfe 183
                     +++++++++vdp +s ++  ++ ++ +++ +v++k ++g+ ++ + wpg+++++D+++p+a+++w+ ++++f+ d   +gvdg+wiDmnep+nf+
      EEA19961.1 338 NHDQQYIMMVDPPVSLND--SASYNAAVDLDVLIKYDNGTtFVATmWPGAVSYVDWFHPNAQSYWTGQIESFFDDqsgVGVDGMWIDMNEPANFC 430
                     ************998766..888************99999955556**************************99789****************** PP

                     CCCHH.HHCCCTS..........................................................................CETTCC.. CS
                     xxxxx.xxxxxxx..........................................................................xxxxxx.. RF
  Glyco_hydro_31 184 egsds.eekeake..........................................................................tkaags.. 201
                      +++s + + a +                                                                          ++   +  
      EEA19961.1 431 GYPCSnPVQVAIDendppappplrttwdpipgfpsdfqppgatsektkrdttsanmtgllgrdllypgyriangvgsltvgtiwtdlSQ---Ygg 522
                     ****9777777669*********************************************************************865444...344 PP

                     ..HHHHCCCHHHHHHHHHHHHHHHHTTTST-EEEESSEETTGGGCTEEE--S-BSSHHHHHHHHHHHHHH.HTTT--SEEEECT-SG.HCHHHHH CS
                     ..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx.xxxxxxx RF
  Glyco_hydro_31 202 ..hydvhnlygllmakatyeglkekkpkkrpfiltRstfaGsqryaahWsGdnassWeslresipallsf.slsGvpfwgaDigGFe.ntteely 292
                       +yd+hnly+ +m + +++gl +++p++rpfi++RstfaG +  ++hW+Gdnas+W ++  si + ++f s++++p++gaD++GF+ +tte l+
      EEA19961.1 523 yvQYDTHNLYASYMIERSRQGLLSRRPSERPFIISRSTFAGDGTRGGHWTGDNASTWAHYLLSIFQNMEFaSIFQMPMVGADVCGFNdDTTETLC 617
                     69********************************************************************9****************999***** PP

                     HHHHHHHTTSSSEEE--STTSS--SHHHHCHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHH---S.EE-HHHH-TT-CCCCC--S-EEETTTEEE CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_31 293 aRWvqlGafsPffrnHsskdakrqepwafgeeveeaarkaielRyrLlPylYtlfyeahetglpv.vrplflefpedektfdiddqfmfGdsLLv 386
                     aRW++lGa++Pf+rnH++ +ak+qe+++++  v++aa+kai  R +Ll+ylYt+fy+++ +g+p  + plf+e+p+d++t di++qf+fG+s+Lv
      EEA19961.1 618 ARWAMLGAWYPFYRNHADISAKYQEFYRWPL-VTAAAQKAIAARFQLLDYLYTAFYQQTVDGSPTtIIPLFFEYPNDPATLDISYQFFFGPSILV 711
                     *****************************99.*******************************96599*************************** PP

                     ----STT-SEEEEEE-.SSEEEETTT--EEES...SEEEEEE.--TTSS-EEEETTEEE CS
                     xxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxx...xxxxxxx.xxxxxxxxxxxxxxxx RF
  Glyco_hydro_31 387 aPvleeeatsvevyLP.ggkWydfwtgekyeg...gqtvelt.apldeiplfvraGaIi 440
                     +Pv+ e+++sv++yLP ++ +ydfwtge+++    ++t++l+ +++++ip+++r+G+I+
      EEA19961.1 712 SPVTVEGSQSVSLYLPpQDIFYDFWTGERVTPngdSNTLNLDnVTYTDIPVHIRGGSIV 770
                     ****999*********999********999885332233333223567**********7 PP

>> NtCtMGAM_N  N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.9   0.1   4.5e-41     2e-37       2     116 .]      39     151 ..      38     151 .. 0.92

  Alignments for each domain:
  == domain 1  score: 127.9 bits;  conditional E-value: 4.5e-41
  NtCtMGAM_N   2 ltadlklagsacsvygndieelkleveyetddrlrvkItdannkryevpeellprpssssssssksdnkelevsvtnepFgfkvtRkstgevlfdtsgg 100
                 +t dl lagsac++yg+d+++lkl vey+td+rl+vkI+d+n++ y++p ++l+ ps +   +s+s++++l +++tn+pF+f+++R s+ge++f+tsg+
  EEA19961.1  39 ITGDLILAGSACNTYGEDLSHLKLLVEYQTDSRLHVKIYDENEQVYQIPRSILNPPSGQ--RDSSSRRSQLVFEYTNNPFSFAIQRSSNGETIFNTSGT 135
                 6899***********************************************99888744..344555557***************************** PP

  NtCtMGAM_N 101 plvfedqflqlstklp 116
                 +l+f+ q+++l+t+lp
  EEA19961.1 136 NLIFQSQYVRLRTSLP 151
                 **************98 PP

>> Gal_mutarotas_2  Galactose mutarotase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.5   0.4   1.1e-13   5.1e-10       3      63 ..     155     217 ..     153     219 .. 0.89

  Alignments for each domain:
  == domain 1  score: 39.5 bits;  conditional E-value: 1.1e-13
                      EEEEEES-SS-SS-TTE..EEEE-----TS-HCC.CTS-SCEEEEEEEE..TCEEEEEE--SSSE CS
  Gal_mutarotas_2   3 hvyGlGEkagplnlrgt..ryrlwntdafgyeaessdplYgsiPfmisl..segyGvfvdnpaet 63 
                       +yG+GE ++++++ +t    +lwn+ +    ++s  +lY s+P++i++  ++++Gvf+ n+  +
       EEA19961.1 155 YIYGIGEDSDSFRRETTgyTRTLWNVGQAFLPTHS--NLYSSHPIYIEMrgGQAHGVFLSNSNGM 217
                      79***************5566*****999888886..**************999*******9766 PP

>> AMP_N  Aminopeptidase P, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0     5e-05      0.23      66     105 ..     720     759 ..     708     763 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 5e-05
                 ...EEEE----HHHHHHH----HHHHHHHHHT-SEEEEGG CS
       AMP_N  66 hkstLfvprkdpekelWdGarlgleeakelfgvdeaepid 105
                 +   L++p++d  +  W+G+r ++++  ++++ d++ ++d
  EEA19961.1 720 QSVSLYLPPQDIFYDFWTGERVTPNGDSNTLNLDNVTYTD 759
                 4678*******************************98876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (894 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       299  (0.0166769); expected 358.6 (0.02)
Passed bias filter:                      256  (0.0142785); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.64u 0.29s 00:00:00.93 Elapsed: 00:00:00.45
# Mc/sec: 5911.09
//
Query:       EEA19962.1  [L=516]
Description: serine carboxypeptidase (CpdS), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.7e-77  261.6   0.4    2.3e-77  261.2   0.4    1.1  1  Peptidase_S10  Serine carboxypeptidase


Domain annotation for each model (and alignments):
>> Peptidase_S10  Serine carboxypeptidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  261.2   0.4   1.3e-81   2.3e-77       9     414 ..      73     497 ..      66     501 .. 0.85

  Alignments for each domain:
  == domain 1  score: 261.2 bits;  conditional E-value: 1.3e-81
                    SEEEEEEEECSTTTTEEEEEEEEE-SS..GTTTS-EEEEE--TTTB-THHHHHHTTSSEEEETTTTSEEEE-TT-GGGCSEEEEE--STTSTT-EE CS
  Peptidase_S10   9 fkqysGYldveeeedkslFYwfvesek..npeedplvlWLnGGPGCsSldGlleElGPfrvnkdstkkleenpysWnkvanvlfldqPvGvGFSys 102
                     ++y+G l+ + + ++slF+wf+ + +  +++++++++WLnGGPGCsSl Gll+E+GPf ++ ++ +++++npys ++++nv+++dqP+G+GFS  
     EEA19962.1  73 GESYAGLLKNTPSGQSSLFFWFFPTANpnQNNKKEITIWLNGGPGCSSLVGLLQENGPFLWQ-SGVYQPVRNPYSFHNLTNVVYIDQPAGTGFSPG 167
                    489*********************9987667788****************************.668****************************** PP

                    TTSSGS--SHHHHHHHHHHHHHHHHHHSTCGTTSEEEEEEETTHHHHHHHHHHHHHTHCCH--SSTSEEEEEEEESE-SBHHHHHCCHHH...HHH CS
  Peptidase_S10 103 ntksdvktddeevaedlyefLkkffekfpeyksrdfyitGESYaGhyvPalakeilkknkkekkkkinLkGlligNglideaeqvnsyve...fay 195
                     ++ +   ++ +va+++ +f k+f+++f    + ++yitGESYaG+y+P++a+ ++k+n+++    +nLkG+ i ++ i++ + + +++     ++
     EEA19962.1 168 PSTVQ---NEVDVANQFKDFWKRFIDTFGMQGY-KVYITGESYAGQYIPYIAEGFIKQNDTQ---YFNLKGIQINDPSINDDSVMIYAPAvaaLNH 256
                    99988...9*******************97766.9************************996...9**************9887776666666444 PP

                    HTTSSH..HHHHHHHHHHHEET...................HHHHHHHHHHHHHHHHHHHHH..HHHHCHCEETTETTSEETTSSEEHHHCTTCCC CS
  Peptidase_S10 196 ehglis..eeeyeslkkacekk...................eeleqesekcanllekaskva..vekenkglnvynileeccklkaelkksstdaq 268
                    + +++   ++ +++++   + k                       + ++  a+  +++++++  ++  n ++n+y+++  c               
     EEA19962.1 257 YSSVFGlnDTFMKHINA-ADAKcgytdflnkaltypppspfP---NLHKANAAGCDTWDQIVtaATLVNPCFNIYHLTDFC----------PFLWD 338
                    44443321222222222.222234558888889999995554...4444444444444443333444678********999..........34667 PP

                    CTTTTTCHHHHHHHHTSHHHHHHTT--TTSSS--SB-H.HHHHHCTCCC-SBCHHHHHHHHHTT-EEEEEEETT-STT-HHHHHHHHHHTECTTEC CS
  Peptidase_S10 269 ggedpydesyvekylnkkeVrkalhvnasvkkweecnd.svfeqleddisksveeileellesglrvliynGdvDlicnvlgteawikklelsgkk 363
                    ++  p + +  ++y+n++ V+ alhv+    +++ c + ++   ++d + +s+   l++++e++ +vli  G +D++  + g+ a+i++++++g++
     EEA19962.1 339 EMGFPSEAQGPNNYFNQAAVQAALHVQ--HTDYSVCGEtNI-FPNGDGSVPSALGPLPRVIEATNNVLIGHGWYDYLLFMNGSLATIQNMTWNGAQ 431
                    88899999*****************86..679****98456.67799999********************************************** PP

                    CSCCCEEEE...............TTTCESEEEEEEEETTEEEEEETT--SSHHHHSHHHHHHHHH CS
  Peptidase_S10 364 efrpwevsp...............kkengqvaGyvkeyenltfltvkgaGHmvPedkpeealqlle 414
                    +fr   +++               ++ +g + G  ++ ++ltf +v+g+GH+ P++ p +a++ le
     EEA19962.1 432 GFRFPPTEAlyvpyeagslvdpvtWSGGGGILGTAHTERGLTFSSVYGSGHEIPQYVPGAAYRQLE 497
                    **98888778899***********************************************998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (516 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       433  (0.0241508); expected 358.6 (0.02)
Passed bias filter:                      387  (0.0215851); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.42
# Mc/sec: 3691.07
//
Query:       EEA19963.1  [L=149]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-47  161.5   0.0    1.4e-47  161.4   0.0    1.0  1  Tautomerase_3  Putative oxalocrotonate tautomerase enzyme


Domain annotation for each model (and alignments):
>> Tautomerase_3  Putative oxalocrotonate tautomerase enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  161.4   0.0   7.8e-52   1.4e-47       1     137 []       1     138 [.       1     138 [. 0.98

  Alignments for each domain:
  == domain 1  score: 161.4 bits;  conditional E-value: 7.8e-52
                    --EEEEEE-TTSS-HHHHHHHHHHHHHHHHHTT--GGG-EEEEEE--TTSEEETTEE-SS.EEEEEEEEETTSS-SHHH..HHHHHHHHHHHHHHH CS
  Tautomerase_3   1 MPlwkiyhpkntftkeekealakkiteiYtsvglPaFyvnvlFieieaedffvGgesrkkpfvritvehiArtlesees..rekllkavdevlkpv 94 
                    MP+wkiyh++nt+t+e+k++l+++it++YtsvglPaFyvn+++++++++dffvGg++++k +++i+v hiAr+++s+e+    +l + ++e+lkp+
     EEA19963.1   1 MPYWKIYHSPNTLTEEDKTTLSASITSYYTSVGLPAFYVNIFYLPLASSDFFVGGKPVSK-KLAIEVLHIARQWDSTETdrAVRLKNGITEILKPY 95 
                    ************************************************************.***************99976778999********* PP

                    HGGGT-EEEEEEEEE-GGG-EETTB----TT-HHHHHHHHHTS CS
  Tautomerase_3  95 iadkglelefhveeterelwkinGlvpPppgseaekewveenr 137
                    ++dkg+++ef+v + + +lw+inG+ pP+  +++++e ve+nr
     EEA19963.1  96 TTDKGVQVEFCVVQGPPQLWRINGIDPPEGVDASNEELVERNR 138
                    ****************************************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (149 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       346  (0.0192983); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.30s 00:00:00.74 Elapsed: 00:00:00.47
# Mc/sec: 944.38
//
Query:       EEA19964.1  [L=312]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      3e-17   62.8  10.2    2.7e-10   40.1   0.8    2.7  3  DUF3112   Protein of unknown function (DUF3112)


Domain annotation for each model (and alignments):
>> DUF3112  Protein of unknown function (DUF3112)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.1     0.078   1.4e+03      53      68 ..      32      47 ..       5      80 .. 0.72
   2 !   28.3   0.8   5.8e-11     1e-06       1      83 [.     125     206 ..     125     213 .. 0.89
   3 !   40.1   0.8   1.5e-14   2.7e-10     154     218 .]     216     281 ..     211     281 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.078
     DUF3112 53 assvliilysllaval 68
                +s+v+++ly l a++ 
  EEA19964.1 32 VSCVFLVLYILAAASH 47
                5566666666555543 PP

  == domain 2  score: 28.3 bits;  conditional E-value: 5.8e-11
     DUF3112   1 PvtGsrklfwvvmlllylvvigvvvmtivasvvpylyflsekhyemckkvvkassvliilysllavalillayllkptkkdek 83 
                 P  G++kl ++v l+ yl++  v++m iv++ v   y+l++ + ++c+ +  a s  ++++sll +al +   + ++++ +e+
  EEA19964.1 125 PRFGWTKLVHNVFLVNYLLIPCVLIMVIVTT-VYAHYTLDSGALKSCRDALLAVSSYMVFFSLLPLALAIGIAMAPKGTDREN 206
                 889***********************99986.5678*******************************9877777777776666 PP

  == domain 3  score: 40.1 bits;  conditional E-value: 1.5e-14
     DUF3112 154 iliiilttlllligavlRavsvfldrtkveespifk.pvvmYilfgllEvivnvlylvgRvDlRFY 218
                 + i+ +t++ll++ga +Ra++ f+  + +++   f+ + ++Yi+++ lEv+v   +l++R+D RF+
  EEA19964.1 216 LWIVGVTSFLLCLGATFRAAVNFMPPRPATNPYSFQgRACFYIFYFTLEVLVVYTFLFTRIDKRFW 281
                 6799*********************996666655552899*************************5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (312 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       715  (0.0398795); expected 358.6 (0.02)
Passed bias filter:                      339  (0.0189079); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2176.45
//
Query:       EEA19965.1  [L=506]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    3.7e-35  121.5  34.4    4.9e-35  121.1  34.4    1.2  1  MFS_1       Major Facilitator Superfamily
      6e-09   34.9  14.8    1.3e-07   30.5   5.3    2.4  3  TRI12       Fungal trichothecene efflux pump (TRI12)
    3.3e-08   32.8   9.8    3.3e-08   32.8   9.8    3.1  3  Sugar_tr    Sugar (and other) transporter
  ------ inclusion threshold ------
      0.027   14.0   2.2        2.2    7.8   0.0    3.5  3  ATP-synt_Z  Putative AtpZ or ATP-synthase-associated
        1.8    8.8   6.8          2    8.6   0.7    2.9  2  DUF4418     Domain of unknown function (DUF4418)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.1  34.4   1.4e-38   4.9e-35       4     353 .]      72     454 ..      69     454 .. 0.79

  Alignments for each domain:
  == domain 1  score: 121.1 bits;  conditional E-value: 1.4e-38
       MFS_1   4 aaflsalarsilgpalpl..alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.sslw.lllvlrvlqGlg 98 
                 +af ++++ +++++++p    ++ dlg+s  + + l++l  +  + a l++ +ls+rfGrr+++l++l++++++  +++ a s+ +  ++++r+l +++
  EEA19965.1  72 VAFHAMFGTFTAAAIIPAyfDISLDLGVSINTTSYLTSLQIAILGGAPLFWKPLSNRFGRRPIFLISLIGSLVC-NIGC-AkSPDYaSMAACRALVAFF 168
                 5555555555555555543378****************************************************.5555.33666669*********** PP

       MFS_1  99 agalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee........k 189
                  + + ++g a++ + f k++r++++g++++ + lG+ + p + g++a+ +++r++++ilai+  + f l +++ pe++   +++ p+  +         
  EEA19965.1 169 ISPAGALGSAVVMECFFKRDRAKYMGVWTLLVTLGVPVSPFIFGFVAQRVSYRWIYWILAIINGVQFFLCIFFQPETRYIGGWDGPVSSGfrqkywsfR 267
                 ******************************************************************998788888888888888888888999888887 PP

       MFS_1 190 gtgpaplvp.....awkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrlsdrlgr.......... 273
                 +  p+p++      +++++ ++ v+  + + + +f f+  + ++ +p +lq  +gl+ + ++gl +  l ++++ +  l+g lsd + r          
  EEA19965.1 268 RIDPTPFTLyefvkPLTMVTRPTVMIPAAAYAMVFLFVSVMCTVEIPQLLQLKFGLD-AQSLGLQFLSLIIGSVLGEQLGGPLSDSWMRwkarrqggqh 365
                 77777777788888888888888885344444444446666999*************.67888777777777777788******995555667777777 PP

       MFS_1 274 ...rrrlllallllllaalglallavt..ssavllll.....vlvliGfglgfv.fpsllalasdlappeeagtasglfntagslggalgp 353
                    + rl+l+++++lla +g++++ v   +s++ ++      +++++ fg  +v +++++++++ ++   ea+++  ++++++++ g++gp
  EEA19965.1 366 aaaEHRLWLSYIGFLLAIAGIVVFLVQtqNSPAGHWNvtpiiGVAIAAFGNQVVtTVLITYAVDTNH--TEAASVGVFITFVRQIWGFIGP 454
                 8887777777777777777777777777544444444444445555666555553444455555555..88888888888**********8 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.5   5.3   3.5e-11   1.3e-07      58     217 ..      81     241 ..      58     251 .. 0.73
   2 ?   -3.5   0.3       0.7   2.5e+03     287     327 ..     274     313 ..     274     317 .. 0.82
   3 !   11.1   0.1   2.5e-05     0.091     237     293 ..     372     426 ..     354     437 .. 0.83

  Alignments for each domain:
  == domain 1  score: 30.5 bits;  conditional E-value: 3.5e-11
       TRI12  58 fvlqasasalpnilqdvgqsensslfst.lwttgqavsilvmgrltdrfgrrpfvilthilglvgaivgctatkfntllaamtllgvaagpaga..spl 153
                 f   a   a  +i  d+g s n++ + t l       + l    l++rfgrrp+ +++ i  lv  i  + +  + ++ a+ +l+     paga  s  
  EEA19965.1  81 FTAAAIIPAYFDISLDLGVSINTTSYLTsLQIAILGGAPLFWKPLSNRFGRRPIFLISLIGSLVCNIGCAKSPDYASMAACRALVAFFISPAGAlgSA- 178
                 44445555667788899999987665551444455566788999*********999988888888775555678999999999999999999874233. PP

       TRI12 154 fvge..lmsnktkflgllivsipvvvtsglspylgqrlaiqgswrwifyiyiitsaiavllivvwy 217
                 +v e  +  +++k++g+ ++ +    +  +sp++   +a + s+rwi++i  i+  +   l +  +
  EEA19965.1 179 VVMEcfFKRDRAKYMGVWTLLVTLG-VP-VSPFIFGFVAQRVSYRWIYWILAIINGVQFFLCIF-F 241
                 334411456899****998766443.33.799999999999*************9998877654.3 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 0.7
       TRI12 287 falyevygkpvrpivppalfkdtrgfvcillissimgamnl 327
                 f+lye + kp   +  p+++  +  +  ++l  s+m ++++
  EEA19965.1 274 FTLYE-FVKPLTMVTRPTVMIPAAAYAMVFLFVSVMCTVEI 313
                 67888.67999999999999999999999999999987765 PP

  == domain 3  score: 11.1 bits;  conditional E-value: 2.5e-05
       TRI12 237 akldwigiilvivgvslfllgvswggkpnspwnsakviglissglgslvvfalyevy 293
                   l +ig +l i+g+ +fl+       p   wn + +ig+  +  g+ vv ++   y
  EEA19965.1 372 LWLSYIGFLLAIAGIVVFLVQ--TQNSPAGHWNVTPIIGVAIAAFGNQVVTTVLITY 426
                 46899*************965..5678*******************99998765555 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.8   9.8   9.3e-12   3.3e-08     281     441 ..      94     246 ..      51     249 .. 0.72
   2 ?   -0.7   0.0      0.14   4.9e+02      48      75 ..     328     355 ..     323     358 .. 0.85
   3 !    3.6   8.4    0.0068        24     331     429 ..     381     480 ..     372     488 .. 0.75

  Alignments for each domain:
  == domain 1  score: 32.8 bits;  conditional E-value: 9.3e-12
                 HHHSS-THH..HHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHH CS
    Sugar_tr 281 fenlglsks..llvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfalgwgpvpwvlvsE 377
                   +lg+s     + t + +++   a +++ +l+ rfGRR+++l++++g ++c +  +       ++     +++++++   +a+f    g +   +v E
  EEA19965.1  94 SLDLGVSINttSYLTSLQIAILGGAPLFWKPLSNRFGRRPIFLISLIGSLVCNIGCA-------KS---PDYASMAACRALVAFFISPAGALGSAVVME 182
                 444555444446777777777888888888888888888888888888888887776.......22...367777777777777777777777888888 PP

                 HSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--ST CS
    Sugar_tr 378 lfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetk 441
                  f ++ R+k + + + +  l   +  ++f +++++++  +++++ a+++ + ++ + ff pet 
  EEA19965.1 183 CFFKRDRAKYMGVWTLLVTLGVPVSPFIFGFVAQRVSYRWIYWILAIINGVQFFLCIFFQPETR 246
                 8888888888888888888888888888888888888888888888888888888888888885 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.14
                 HHHHHHTHHHHHHHHHHHHHHHHHHTTH CS
    Sugar_tr  48 sglivsiflvGaiiGslfagllgdrfGR 75 
                 +gl + ++++G+++G  ++g+l+d + R
  EEA19965.1 328 LGLQFLSLIIGSVLGEQLGGPLSDSWMR 355
                 6788999****************98755 PP

  == domain 3  score: 3.6 bits;  conditional E-value: 0.0068
                 HHHHH..HHHHTTSS......CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHH CS
    Sugar_tr 331 fvilgivalllvaks...kaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfagla 426
                 ++i giv++l+++++     +++  i+++a+ +a+ +  +++v+  ++ ++  ++  s++  i++ v  ++ f+  + fp ++e++g +++  v a+l+
  EEA19965.1 381 LAIAGIVVFLVQTQNspaGHWNVTPIIGVAI-AAFGNQVVTTVLITYAVDTNHTEAASVGVFITF-VRQIWGFIGPFWFPDMFEKVGVAKSAGVAAALL 477
                 3344455555555555754555666666665.4888899*********************98865.6779*****************999988888887 PP

                 HHH CS
    Sugar_tr 427 vlf 429
                 v +
  EEA19965.1 478 VGV 480
                 755 PP

>> ATP-synt_Z  Putative AtpZ or ATP-synthase-associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0      0.28     1e+03       4      18 ..     108     122 ..     106     125 .. 0.87
   2 ?    7.8   0.0   0.00062       2.2      26      48 ..     368     390 ..     363     393 .. 0.89
   3 ?    3.3   0.1     0.016        58       2      28 ..     474     500 ..     473     502 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.28
  ATP-synt_Z   4 lsllvsvaGaalLaw 18 
                 +sl +++ G+a L w
  EEA19965.1 108 TSLQIAILGGAPLFW 122
                 68999******9998 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.00062
  ATP-synt_Z  26 tnsqLWmVPvGLvLlvTpvivwl 48 
                 ++++LW+  +G++L++  ++v+l
  EEA19965.1 368 AEHRLWLSYIGFLLAIAGIVVFL 390
                 6789*****************98 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.016
  ATP-synt_Z   2 allsllvsvaGaalLawWavayhptns 28 
                 a+l++ vs++  +lL w   a+++t++
  EEA19965.1 474 AALLVGVSLIPTMLLQWRGQAWRRTEK 500
                 578999****************99975 PP

>> DUF4418  Domain of unknown function (DUF4418)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.7     0.061   2.2e+02      28      50 ..     175     202 ..     135     240 .. 0.63
   2 ?    8.6   0.7   0.00056         2      40      81 ..     376     417 ..     371     440 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.061
     DUF4418  28 m.....MkChytgqaelgvGivllvlgl 50 
                 +     M+C++    + ++G+ +l+++l
  EEA19965.1 175 LgsavvMECFFKRDRAKYMGVWTLLVTL 202
                 2333669999888888888888777765 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.00056
     DUF4418  40 gvGivllvlgllalfvkkkklrrglsiavillgvlviliptv 81 
                 ++G +l+++g++ ++v++++  +g + ++ ++gv+++++ ++
  EEA19965.1 376 YIGFLLAIAGIVVFLVQTQNSPAGHWNVTPIIGVAIAAFGNQ 417
                 79**************************99999999776544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (506 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       742  (0.0413855); expected 358.6 (0.02)
Passed bias filter:                      350  (0.0195214); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.56u 0.30s 00:00:00.86 Elapsed: 00:00:00.45
# Mc/sec: 3379.35
//
Query:       EEA19966.1  [L=521]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.046   13.6   0.5      0.083   12.8   0.5    1.3  1  DUF2637   Protein of unknown function (DUF2637)


Domain annotation for each model (and alignments):
>> DUF2637  Protein of unknown function (DUF2637)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.5   4.7e-06     0.083      80     154 ..     197     274 ..     181     283 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 4.7e-06
     DUF2637  80 wiNgiea....tdvtlkvvaaalslaanvafelvlaaarrrieeragllaakappelrllralvpplatlaatrrvkal 154
                 wiN+++     t   +  +  a+sla+ va+ ++ ++ + r+  r+ +++  +p +l  l+  +++ at + t +v+++
  EEA19966.1 197 WINALNLasiaTCALPSAIGFAVSLAIMVATNIAMETQA-RYRTRQTQQRILPPSGLYCLVMRWDSSATNRRTTNVDLN 274
                 788777766655666788999************999985.777777777777789**************9999998773 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (521 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       595  (0.0331865); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.42
# Mc/sec: 3736.16
//
Query:       EEA19967.1  [L=327]
Description: chitinase 1 precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.9e-21   75.1   2.1    3.1e-20   73.1   2.1    1.7  1  Glyco_hydro_18  Glycosyl hydrolases family 18


Domain annotation for each model (and alignments):
>> Glyco_hydro_18  Glycosyl hydrolases family 18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.1   2.1   1.8e-24   3.1e-20       3     227 ..      33     264 ..      31     305 .. 0.72

  Alignments for each domain:
  == domain 1  score: 73.1 bits;  conditional E-value: 1.8e-24
                     EEEEEGGGGGSS.G.CSHTTTESEEEEEEEEEEE................TTTEEEESSTTHH..........HHHHHHHHHHHHTSTT-EEEEE CS
                     xxxxxxxxxxxx.x.xxxxxxxxxxxxxxxxxxx................xxxxxxxxxxxxx..........xxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18   3 vgYysswesygn.n.ylpsaklthiiyaFakidg................engkvvvsdwedl..........gnfeqlkklkkkknpgvkvlls 69 
                      +Y++   +++  + +   + ++++++aF++ ++                +          +           +  + ++++ + ++ ++ v++s
      EEA19967.1  33 TVYWGAEDATTTlSdVCSDDSYQIVNLAFVSYFNgdggyptlslstldgpS----------QAqqdagatslqDGSSLVDAIQACQSSEKLVIMS 117
                     67887666554433336699***********99999999555555554440..........444555555554344466777777777999**** PP

                     EEETTTTTHHHHHHTSH.HHHHHHHHHHHHHH...........HHCT...-SEEEEEES-TTTSTCHHHHHHHHHHHHHHHHHHHHHHTSTTCEE CS
                     xxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxx...........xxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18  70 iGGwtdssgfslaastd.asrkkfadsvvsll...........rkyg...fDGiDidweypggnpedkenytallkelrealdkakategkkllL 149
                     +GG+ +   +s+++ +  ++++++ad ++sl+           r++g   +DG+Did e  g    d ++y++++++lr+ + +++    k+++L
      EEA19967.1 118 LGGDVG---YSDVTFSGdDQANEVADMLWSLFgggtdesinplRPFGdvkLDGFDIDNE-SG----DPTGYSTFVSRLRSNFAQDS---SKTYYL 201
                     *****7...77776554499********************9997777888*********.43....699***********999554...799*** PP

                     EEEEESSHHHHHHHCHHHHHHHHTSEEEEETTTSSS....TTSSBE--SS-SSBTCSSHHHHHHHHHHTT--GGGEEEEEES CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18 150 saavpasasdlskgydlpkiakylDyvnvmtYDfhg....swdnvtghhaplydaslnvdeavkeylkagvpakklvlGvpf 227
                     +aa+++ ++d   +    ++ + lDyv+v++Y+  +    +                   +av+++  +g+  +kl++G  +
      EEA19967.1 202 TAAPQCVYPDK--S-IPLDVCQQLDYVWVQFYNNGDcdvaQ---------------SGFIDAVQNWS-EGIGDAKLFIGAIA 264
                     **********3..2.34556899*********777633320...............23333444444.23446666666554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (327 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       389  (0.0216967); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.30s 00:00:00.79 Elapsed: 00:00:00.47
# Mc/sec: 2109.69
//
Query:       EEA19968.1  [L=537]
Description: maltose permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-88  297.1  18.5    2.6e-88  296.9  18.5    1.0  1  Sugar_tr  Sugar (and other) transporter
    1.3e-16   60.5  28.0    4.3e-16   58.8  22.2    2.5  3  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  296.9  18.5   2.9e-92   2.6e-88       6     452 .]      58     511 ..      53     511 .. 0.93

  Alignments for each domain:
  == domain 1  score: 296.9 bits;  conditional E-value: 2.9e-92
                 HHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TG CS
    Sugar_tr   6 alggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvev 104
                 +++ +++gYd+ ++ +f+++++fa+++g ++s+++++ ++ +++ + + ++vG+i+G ++ g++++r+G++ +++++ + +   +++ ++a    ++e 
  EEA19968.1  58 STAIIMEGYDVVLMQSFYAFPEFANRYGHKTSDGDYQITAPWQSGLSNGANVGEILGLFINGIVSERYGYRFTMIVSLTALTCFIFIPFFAS---NIET 153
                 55669*****************************99999*****************************************************...9*** PP

                 GGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHH.HTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHHTT CS
    Sugar_tr 105 livgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglgl.nktsnadgwrillglqlvpallllilllflPESPrylvekg 202
                 l vg +l+Gi++G++++l++ y+sE++p  lRg+l+++ ++++ +G+l+aa++  gl n++++ + +ri+++lq+++++ l+++++++PESP++lv k+
  EEA19968.1 154 LEVGEILMGIPWGVFQTLTTAYASEVCPVVLRGYLTTYVNVCWGIGQLIAAGVLRGLlNRSDQ-WAYRIPFALQWIWPVPLIVGICLAPESPWWLVRKD 251
                 *********************************************************666666.*********************************** PP

                 -HHHHHHHHHHHHHC....HHHHHHHHHHHHHHHHHHH..........HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH..H CS
    Sugar_tr 203 keeeakevlaklrge....edadrelaeekdsleaeqeee.....kaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsks..l 290
                 + +ea++ l +l  +    +d + ++++ ++++ +++  e      +s+   ++    ++r+ i++v++++q+l+G +a+m ys+++f+++gls s  +
  EEA19968.1 252 RVDEAQKALLRLTSQrpniSDSTFDVDQTIAMMVHTDALErrltsGTSYLDCFRGS-DLRRTEIVCVTWAIQNLCG-AAFMGYSSYFFRQAGLSVSysF 348
                 ***********877777886777777777777777766556666866666666663.69*****************.9****************9999* PP

                 HHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH...HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHH CS
    Sugar_tr 291 lvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilg.ivalllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskal 388
                  +++ +++v ++ +f+++f++ ++GRRtl+l G++ m+i ++i+g  +++  +++    + v+  +++ ++ l+ +++g+v + +v+E+ + ++R+k++
  EEA19968.1 349 DMSMALYAVAIIGVFASWFFMTHWGRRTLYLSGLVSMCIILLIIGlVAVDDKSTN---SGWVIGSLLLAYTLLYDITVGTVAFSIVAEIPSCRLRTKTI 444
                 *********************************************4444444444...5899999999******************************* PP

                 HHHHHHHHHHHHHHHHHHHHHHCHHH...T-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 389 aiavavnwlanflisllfpiiteaig...ggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                  +  ++ +++ ++ ++++p++++ ++   +g+ ++++ag + l +++++f +pe kgrt+ee++ lf
  EEA19968.1 445 VLGRNLYNVIGIINGVITPYMLNPSTwnwKGKAGFFWAGSCFLCLVWTYFRLPEPKGRTFEELDLLF 511
                 ***********************9999999********************************99766 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.1     0.078     7e+02     193     241 ..      35      87 ..      20     115 .. 0.57
   2 !   58.8  22.2   4.8e-20   4.3e-16      40     322 ..     106     427 ..      51     441 .. 0.75
   3 !    5.0   0.7    0.0011        10     108     188 ..     429     510 ..     422     528 .. 0.64

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.078
       MFS_1 193 paplvpawkallkdpvl..willialllfffgfsg.......lltllplylqevlgls 241
                 +++l+  w+a++  p    w    ++l++++++ g        ++ +p +   ++g +
  EEA19968.1  35 EHNLTL-WQAIRLYPKAigW---SIFLSTAIIMEGydvvlmqSFYAFPEF-ANRYGHK 87 
                 445555.9999999977344...333333333333333433344444444.5555554 PP

  == domain 2  score: 58.8 bits;  conditional E-value: 4.8e-20
       MFS_1  40 lyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailg. 137
                 +  +g +++ ++ G +s+r+G r +++++l+++  ++++++fas++ +l v+ +l+G+  g++ ++  a+++++ p   rg  + ++++++++G +++ 
  EEA19968.1 106 GANVGEILGLFINGIVSERYGYRFTMIVSLTALTCFIFIPFFASNIETLEVGEILMGIPWGVFQTLTTAYASEVCPVVLRGYLTTYVNVCWGIGQLIAa 204
                 4667889999999*******************999999999989999************************************************8884 PP

       MFS_1 138 pllgglla..sslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......................................kgtgpap 195
                  +l gll   +++ +r +f +  i  + ++v +++l pe+p    rk  ++e                                        +gt    
  EEA19968.1 205 GVLRGLLNrsDQWAYRIPFALQWIWPVPLIV-GICLAPESPWWLVRKDRVDEAqkallrltsqrpnisdstfdvdqtiammvhtdalerrltSGTSYLD 302
                 7777777754455577777777766666655.3355544444444444444435555566788899999999999999999998888887777777777 PP

       MFS_1 196 lvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrls.drlgrrrrlllallllllaalglal 293
                 ++   + l++   +  +++ ++ + +g +++ + + ++   + gls + ++  ++++l++v++i+  +a+++  +++grr+  l +l+++ +++l++ l
  EEA19968.1 303 CFR-GSDLRRTEIV--CVTWAIQNLCGAAFMGYSSYFF--RQAGLS-VSYSFDMSMALYAVAIIGV-FASWFFmTHWGRRTLYLSGLVSMCIILLIIGL 394
                 777.9999999977..8888888876666666666665..556666.4444444666666666654.5555555************************* PP

       MFS_1 294 lavt...ssavllllvlvl.iGfglgfvfpsll 322
                 +av    +++ +++ +l+l +++ + +++++++
  EEA19968.1 395 VAVDdksTNSGWVIGSLLLaYTLLYDITVGTVA 427
                 ***999888888888776664444444433332 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.0011
       MFS_1 108 aliadwfpkeergraigllsagfslGailgpllggllasslgWrav...fyilaivsllafvlfllllpeepperkrkspkeee 188
                 +++a++ + + r++ i l    +++  i+  ++ ++++    W +     ++ a+ ++l+  l++ +++ ++p+ +++++ +++
  EEA19968.1 429 SIVAEIPSCRLRTKTIVLGRNLYNVIGIINGVITPYMLNPSTWNWKgkaGFFWAGSCFLC--LVWTYFRLPEPKGRTFEELDLL 510
                 555555555566666666666666666666666666664444555422477777777777..6789999999999998888774 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (537 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       825  (0.0460148); expected 358.6 (0.02)
Passed bias filter:                      436  (0.0243181); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.25s 00:00:00.83 Elapsed: 00:00:00.40
# Mc/sec: 3992.12
//
Query:       EEA19969.1  [L=442]
Description: O-methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.4e-19   70.2   0.0    2.8e-19   69.3   0.0    1.4  1  Methyltransf_2   O-methyltransferase domain
  ------ inclusion threshold ------
      0.017   14.9   0.0      0.062   13.1   0.0    1.9  1  Methyltransf_31  Methyltransferase domain
      0.024   14.2   0.0      0.049   13.2   0.0    1.5  1  Sigma70_r4       Sigma-70, region 4
      0.094   12.2   0.0       0.67    9.4   0.0    2.2  2  CheR             CheR methyltransferase, SAM binding domain
       0.18   11.9   0.0        2.6    8.2   0.0    2.3  2  Sigma70_r3       Sigma-70 region 3


Domain annotation for each model (and alignments):
>> Methyltransf_2  O-methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.3   0.0   7.8e-23   2.8e-19      38     207 ..     236     417 ..     221     419 .. 0.84

  Alignments for each domain:
  == domain 1  score: 69.3 bits;  conditional E-value: 7.8e-23
                     HHHHHHHTTHHHHHHHHHH.SS-GGG-..SEEEEET-TTSHHHHHHHHH-TT-EEEEEE-HHHHHHHHHHS-----TTEEEEES-TTTS---.-- CS
  Methyltransf_2  38 kfnkglqessslvakkvle.afdlegl..kslvDvGGGtGalakaivsayPtikvivfDlpeVveaAkehlsageeervefvgGdffkdslP.ea 128
                       +++ +  s + +++ l+ ++d  +l   +++D+GG +G  a   ++a+P+++++v D pe   + +  l ++++erv f+  dff  + P +a
      EEA19969.1 236 EAMQAAAAASGVAVNEYLRdNYDWASLgeAKVIDMGGSSGHDAFVLAKAFPKLSLVVQDRPELEPSFRALLPQELSERVLFQPHDFF-TPQPvKA 329
                     33455556677777777753688776622579************************************999****************.88888** PP

                     SEEEEESSGGGS-HHHHHHHHHHHHHH--TT-EEEEEE--...--TTS---HHHHHH......HHHHHHCSS-----HHHHHHHHHHC CS
  Methyltransf_2 129 DaillkrvlhDwsdekcvklLkrvkkalpagGkvivveav...lgadpsgeletelv......dlimlvqteGkeRteaeyeellsea 207
                     D++++k++ hDw d+ + k+L+++   l++g ++++ e+v   l+a+++ +l    +      dl m+  ++  eRt +e+++++++a
      EEA19969.1 330 DVYVVKQIFHDWPDKYVIKILENIAPHLKSGSRLVMFESVfpsLDAEGKYPLPPAAMrmlaatDLQMITFANAVERTLEEWHAVVKKA 417
                     ***************************************965556666655433322344889********************99987 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   1.7e-05     0.062       5     114 ..     265     375 ..     262     418 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.7e-05
  Methyltransf_31   5 lrvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielArenaqklgldnveFeqgdiee.leklledekfDlilsnevlnaladp..dkile 95 
                       +v+D G  +G+++f+la +++pk  +v  D+ e    + r+ + +  +++v F+  d+++  +      k D+ + ++++++ +d+   kile
       EEA19969.1 265 AKVIDMGGSSGHDAFVLA-KAFPKLSLVVQDRPE-LEPSFRALLPQELSERVLFQPHDFFTpQP-----VKADVYVVKQIFHDWPDKyvIKILE 351
                      689***************.999999988888755.444557788889999***********556.....569**************96579*** PP

  Methyltransf_31  96 eiervlkpggilliedpr.....l 114
                      +i   lk+g++l++ +       +
       EEA19969.1 352 NIAPHLKSGSRLVMFESVfpsldA 375
                      **************9988555552 PP

>> Sigma70_r4  Sigma-70, region 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   1.4e-05     0.049      20      45 ..     106     131 ..      97     133 .. 0.91

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.4e-05
                 T--HHHHHHHHTS-HHHHHHHHHHHH CS
  Sigma70_r4  20 glTleEIgerlgiSrerVrqiekrAl 45 
                   T++EI er  +++e Vr+i+++A+
  EEA19969.1 106 SATYSEIVERTKLPEEVVRRILRYAF 131
                 68**********************98 PP

>> CheR  CheR methyltransferase, SAM binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0      0.18   6.5e+02      31      53 ..     263     285 ..     247     297 .. 0.81
   2 ?    9.4   0.0   0.00019      0.67     113     173 ..     307     365 ..     295     370 .. 0.87

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.18
                 SSEEEEEES-TTTHHHHHHHHHH CS
        CheR  31 krvriwsagcssGeEpYslAmll 53 
                  + ++   g ssG+ ++ lA ++
  EEA19969.1 263 GEAKVIDMGGSSGHDAFVLAKAF 285
                 67789999*********999765 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.00019
                 -HHHHTTEEEEE--TTT-SGGG--EEEEEE-SSGGGC-CHHHHHHHHHHHCCEEEEEEEEE CS
        CheR 113 kkeikelvkFeklnllekksvlgklDvifcrnvliYfdeetqekvlerfaeklkpgglLll 173
                  +e+ e+v F++++ ++  + + k Dv + + ++     +   k+le++a +lk g++L++
  EEA19969.1 307 PQELSERVLFQPHDFFT--PQPVKADVYVVKQIFHDWPDKYVIKILENIAPHLKSGSRLVM 365
                 5899*************..666678999999999988899999***************986 PP

>> Sigma70_r3  Sigma-70 region 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0      0.15   5.5e+02      42      66 ..      68      92 ..      66      96 .. 0.87
   2 ?    8.2   0.0   0.00073       2.6      18      44 ..     104     130 ..     102     137 .. 0.89

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.15
                HHHXXXEETTXBSSSSTTXBSTTTX CS
  Sigma70_r3 42 eaarepvSldlpvgeeedtelgdll 66
                 +  e+ Sl +p++++ dt  +d+l
  EEA19969.1 68 AMGPESYSLLHPIFNNHDTMVMDVL 92
                567899*************999987 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.00073
                 SSXXXHHHHHHHHTXXHHHHHHHHHHH CS
  Sigma70_r3  18 grePtpeEiAeeLglseekVrevleaa 44 
                 g ++t  Ei e+++l+ee Vr++l+ a
  EEA19969.1 104 GGSATYSEIVERTKLPEEVVRRILRYA 130
                 568999******************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (442 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       401  (0.022366); expected 358.6 (0.02)
Passed bias filter:                      384  (0.0214178); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 2957.67
//
Query:       EEA19970.1  [L=235]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.7e-06   25.5   2.4    1.6e-05   24.6   2.4    1.5  1  FAD_binding_4  FAD binding domain
  ------ inclusion threshold ------
       0.26   10.0   0.1       0.33    9.6   0.1    1.1  1  RdRP_3         Viral RNA dependent RNA polymerase


Domain annotation for each model (and alignments):
>> FAD_binding_4  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.6   2.4   1.8e-09   1.6e-05      28     138 ..       2     101 ..       1     102 [. 0.84

  Alignments for each domain:
  == domain 1  score: 24.6 bits;  conditional E-value: 1.8e-09
                    EEESSSTTEESTTCSCCEEEEEETTS--EEEEETTTTEEEEETTSBHHHHHHHHHHHTTECSSGGGTTCGSBHHHTTTTT-EETTEEGG--HHGTE CS
  FAD_binding_4  28 lvrGgGssllgqavatggvvldlsrlnrileideeegtatveaGvtlgdlvealaakglllglepgsgipgtvGGaiatnagGygsekyGlirdnv 123
                    ++rGgG++  g       +v+++ + +++l+++  ++ +++ +G   ++++  +  + + +++  g + ++++ G+  ++++G  s ++G+++ n+
     EEA19970.1   2 TIRGGGHDSYGR------TVVST-AAQSFLDHN--RQSCRAWSGNYSHRAASSA--RWRRAQHTDGWVGSVGMVGWSCGGGYGLSSGTWGMVAANI 86 
                    566666665554......58999.788877777..7999*******99999988..667777778889999999********************** PP

                    EEEEEEETTSEEEEE CS
  FAD_binding_4 124 lglevvladGevvrl 138
                    lg++v+ adG+++++
     EEA19970.1  87 LGAKVMQADGHIIDT 101
                    ************987 PP

>> RdRP_3  Viral RNA dependent RNA polymerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.1   3.7e-05      0.33     354     403 ..      23      72 ..      18      92 .. 0.90

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 3.7e-05
                 EEE-TTS-EEEEEEE-SHHHHHHHHHHHH-SCESHHHHHHHTTTSHHHHH CS
      RdRP_3 354 vdgekygmvrnpltslskdplslaswetakpvkswlgaigecglaltggv 403
                 +++++   +r ++   s ++ s a+w++a++   w+g++g+ g++  gg+
  EEA19970.1  23 FLDHNRQSCRAWSGNYSHRAASSARWRRAQHTDGWVGSVGMVGWSCGGGY 72 
                 566678899***********************************998886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (235 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       348  (0.0194099); expected 358.6 (0.02)
Passed bias filter:                      278  (0.0155056); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.27s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1728.87
//
Query:       EEA19971.1  [L=116]
Description: hypothetical protein PMAA_007380 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (116 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       319  (0.0177924); expected 358.6 (0.02)
Passed bias filter:                      303  (0.0169); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.28s 00:00:00.68 Elapsed: 00:00:00.46
# Mc/sec: 764.90
//
Query:       EEA19972.1  [L=358]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      1e-08   35.2   0.0    1.8e-08   34.4   0.0    1.4  1  Abhydrolase_2  Phospholipase/Carboxylesterase


Domain annotation for each model (and alignments):
>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.4   0.0     1e-12   1.8e-08       4     146 ..     103     263 ..     100     275 .. 0.76

  Alignments for each domain:
  == domain 1  score: 34.4 bits;  conditional E-value: 1e-12
                    EEEE--SS---EEEEEE--TT--S.........HHHHHHHH.TT--TTEEEEEE---EEE-GGGTT-EEE-SS-B--SSTTS.-B-HH..HHHHHH CS
  Abhydrolase_2   4 aevvspkdkaqavviflHGlGdsg.........hawaeaakteaalpnikfifphgpelpvtlnggmrmpaWfdlvglspek.kedea..gikksa 87 
                    + v +p+  ++++ i lHG G+sg           + +     ++lp   ++fp +  + +t        +Wfd ++ ++ + ++d +  g  +s+
     EEA19972.1 103 PYVHAPQGLHTNTAIILHGRGSSGpefaedflfSQTLDGKGLASRLPGWRWVFPTSCTRWSTRFEED-IHSWFDAYSQTDINeRSDLQlpGLRESV 197
                    56899999****************8888654443344444567899************998876666.58*****998887744433222778888 PP

                    HHHHHHHHHHHHTT.--GGGEEEEEETHHHHHHHHHHHT-SS......--SEEEEES---TTGGGT CS
  Abhydrolase_2  88 ekleelidaelkkg.ipssriiigGFSqGaalalylaltlpk......klggivafsgalplsqkl 146
                      + e+i+ e       +sri +gG SqG a a  + l  +       ++gg ++f g++p +  +
     EEA19972.1 198 VDILEVIERETGLLdGRASRIYLGGISQGMATASWTLLCRTAigqhqePIGGFLGFCGWIPFANRM 263
                    888888888877767889***********8887665554332233345************988766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (358 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       254  (0.014167); expected 358.6 (0.02)
Passed bias filter:                      242  (0.0134977); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 2418.10
//
Query:       EEA19973.1  [L=554]
Description: MFS multidrug transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-35  123.1  51.7    1.8e-32  112.7  29.5    2.4  3  MFS_1     Major Facilitator Superfamily
    0.00081   18.1  20.4      0.058   12.0  11.6    2.4  2  ATG22     Vacuole effluxer Atg22 like
     0.0016   18.6   0.7     0.0016   18.6   0.7    2.1  2  Pox_A14   Poxvirus virion envelope protein A14
     0.0077   16.8   0.0      0.013   16.0   0.0    1.3  1  FliG_N    FliG N-terminal domain
  ------ inclusion threshold ------
      0.097   12.5   1.2       0.98    9.3   0.2    3.4  2  LapA_dom  Lipopolysaccharide assembly protein A domain


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.7  29.5     5e-36   1.8e-32       2     271 ..      48     301 ..      47     306 .. 0.87
   2 !   22.1   8.3   1.7e-08   5.9e-05     196     352 ..     309     466 ..     300     467 .. 0.82
   3 ?   -3.5   0.1       1.1   3.8e+03      32      49 ..     521     538 ..     497     542 .. 0.61

  Alignments for each domain:
  == domain 1  score: 112.7 bits;  conditional E-value: 5e-36
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgag 100
                 ++a+fls+   +i++++l   ++++l    +   +++t y l++  +  +++ lsd +Gr+ ++++gl++f+l+++l+ ++s++  l+v+r++qG+ga+
  EEA19973.1  48 WIALFLSTVETTIVSTSLV-SITNALS-GFDKRDWIVTSYLLTYTGFLTIYAKLSDILGRKTMFIVGLASFSLFSILCGISSNIVELIVFRAFQGFGAS 144
                 89*****************.9999999.899999****************************************66666568888************** PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeeekgtgpaplvpa 199
                 +++++ ++++  + p+ + +++i+l+s+ f+l++++gpl gg++++s+ W +vf+++a++++la  ++++ lp +  + +  s+ke       ++ ++ 
  EEA19973.1 145 GIYSMTLVIAPTIIPPGQMPKYIALISTVFALASVVGPLMGGAITESGQWKWVFLFNAPAGFLASAVIIFTLPSTSNPGSQLSTKET-----SQQKLS- 237
                 ****************************************************************88655555555555555555555.....566666. PP

       MFS_1 200 wkallkdpvlwillialllfffgfsg.lltllplylqevlglsglllaglllallalvgailallagrlsdrl 271
                 +k l++      ++ ++ll +   s+ l++ + + +  ++g++   ++ ++  +++++++++++++  ++++ 
  EEA19973.1 238 LKNLRRID----YIGVALLLA--ASIlLVFAFES-AGIQYGWN--SITIIVTLIFGFAIFFSFIIWEMWLQKR 301
                 69999999....888888884..44414444444.5*******..89999999999999999****9998775 PP

  == domain 2  score: 22.1 bits;  conditional E-value: 1.7e-08
       MFS_1 196 lvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglall 294
                 ++p   ++lk++   ++++a+++ +f f+++++ +p  +q v+ +s   + +++  l+ l++ +la +a+ l++  g+ ++ +l ++++++  +g+ l+
  EEA19973.1 309 IFP--PQILKSRITASMFAASFFLGFPFTSVVINIPQRAQAVYAFS--SQHAGITLLPLLLTSPLATVASGLLTSNGKVPPVYLVMAGAVTQIIGMGLT 403
                 445..4566666444677777777789999*******9********..777778888888888998888888878799999999999999999999999 PP

       MFS_1 295 avt.....ssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfntagslggalg 352
                         + ++  + + +++G+g+g++ +++l+la  +a ++     +g+ + ++ l+g +g
  EEA19973.1 404 CSLptdtlKFPSQQYGFEAIMGIGFGLTLSTILTLAPLVADERDLPVTMGALTQIRVLSGTFG 466
                 8886666666666666*************************99999******99999999887 PP

  == domain 3  score: -3.5 bits;  conditional E-value: 1.1
       MFS_1  32 seigllltlyalgaavas 49 
                  +++++l++++++a+++s
  EEA19973.1 521 NQQNIVLAVFSAAALFSS 538
                 345555555555555544 PP

>> ATG22  Vacuole effluxer Atg22 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0  11.6   1.6e-05     0.058     351     458 ..     107     205 ..      47     220 .. 0.72
   2 !   11.0   1.3   3.4e-05      0.12     200     258 ..     244     307 ..     217     335 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 1.6e-05
       ATG22 351 ktllaiivlfeliplyGllGiilgkiGlkqpwEfyvlavvyglvlgglssysRslfseLiPrGkEaaFFsLyaitdkgssvigplivglItDrtgnirs 449
                 +++++ ++ f+l+ +   +          + +E+ v+ ++ g+  +g++s+  ++   +iP+G+  ++ +L +++   +sv+gpl+ g+It+  g+ + 
  EEA19973.1 107 TMFIVGLASFSLFSILCGI--------SSNIVELIVFRAFQGFGASGIYSMTLVIAPTIIPPGQMPKYIALISTVFALASVVGPLMGGAITE-SGQWKW 196
                 4444444444444332222........35679**********************************************************96.589999 PP

       ATG22 450 afvflavLl 458
                  f+f+a   
  EEA19973.1 197 VFLFNAPAG 205
                 999998544 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 3.4e-05
       ATG22 200 igylgailvqiisilivialgsta.....tfslrlalllvGlwWliftipaalllkkrpgpplp 258
                 i y+g  l+++ sil+v+a +s       +    ++ l+ G+  ++  i++ ++l+kr+ + ++
  EEA19973.1 244 IDYIGVALLLAASILLVFAFESAGiqygwNSITIIVTLIFGFAIFFSFIIWEMWLQKRQDHFSE 307
                 78*******************98899986666667777888888888899********987655 PP

>> Pox_A14  Poxvirus virion envelope protein A14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.1       3.7   1.3e+04      59      74 ..     110     125 ..     106     135 .. 0.58
   2 !   18.6   0.7   4.3e-07    0.0016      13      73 ..     243     302 ..     236     319 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 3.7
     Pox_A14  59 llglllfsmygrkCka 74 
                 ++gl  fs +   C +
  EEA19973.1 110 IVGLASFSLFSILCGI 125
                 5566666666666644 PP

  == domain 2  score: 18.6 bits;  conditional E-value: 4.3e-07
     Pox_A14  13 tvliaGiiLLilacifafvdfskststtdkawralsi.vsFilgivillglllfsmygrkCk 73 
                  + ++G++LL +a i+  + f  ++   ++ w +++i v+ i g +i  + ++++m+ +k +
  EEA19973.1 243 RIDYIGVALLLAASILLVFAFESAGI--QYGWNSITIiVTLIFGFAIFFSFIIWEMWLQKRQ 302
                 56689***********9999998888..899****962689****************88765 PP

>> FliG_N  FliG N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   3.7e-06     0.013       2      65 ..     461     524 ..     460     537 .. 0.89

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 3.7e-06
                 XXHHHHHHHHHHHCXHHHHHHHHTTSXHHHHHHHHHHHHCHTTXXHHHHHHHHHHHHHHHHCCC CS
      FliG_N   2 LsgvqkaAilllaLgeeeaaevlkhLdeeeiekltkeiaslksvskeeveaVleefleeleaqe 65 
                 Lsg+   Ai   +L +  ++++   Ld++e++++++++  +ks+s+ +  +V   f e +++q+
  EEA19973.1 461 LSGTFGLAISATVLNDHVTSRLSTTLDPQELAAISNSLGAIKSLSPTQQSEVRVAFAEGFNQQN 524
                 56666678888999999*******************************************9875 PP

>> LapA_dom  Lipopolysaccharide assembly protein A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.2   0.00027      0.98      20      47 ..     274     301 ..     273     305 .. 0.82
   2 ?   -3.3   0.0       2.3   8.3e+03      25      37 ..     326     339 ..     323     346 .. 0.64

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00027
    LapA_dom  20 sllllvafgiGallgwllslwsylrlrr 47 
                 s+ ++v++++G+ + + + +w ++ ++r
  EEA19973.1 274 SITIIVTLIFGFAIFFSFIIWEMWLQKR 301
                 6789*****************6664444 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 2.3
    LapA_dom  25 vafgiGa.llgwll 37 
                 ++f++G+ +  +++
  EEA19973.1 326 ASFFLGFpFTSVVI 339
                 67888885555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (554 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       706  (0.0393775); expected 358.6 (0.02)
Passed bias filter:                      302  (0.0168442); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 3688.18
//
Query:       EEA19974.1  [L=275]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      1e-55  188.9   3.7    1.2e-55  188.7   3.7    1.0  1  Glyco_hydro_cc  Glycosyl hydrolase catalytic core
  ------ inclusion threshold ------
       0.06   12.6   2.4      0.092   12.0   2.4    1.2  1  Glyco_hydro_72  Glucanosyltransferase


Domain annotation for each model (and alignments):
>> Glyco_hydro_cc  Glycosyl hydrolase catalytic core
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  188.7   3.7   1.3e-59   1.2e-55       2     239 .]      30     272 ..      29     272 .. 0.89

  Alignments for each domain:
  == domain 1  score: 188.7 bits;  conditional E-value: 1.3e-59
  Glyco_hydro_cc   2 layn.....adasddkllsaksskisWyYnwsskpsselssaalefvPmlwgaksad.tdalanvksaakenskylLgFNePDlks..qsnmspe 88 
                     l+yn      da+ ++++ a ss+++W+Y+w+  ps +ls   +efvPmlwg  s d  d++++v+ a   +   +LgFNePDl+   +sn+ p+
      EEA19974.1  30 LVYNnnnvyGDATYANDFFAISSQVTWAYDWGY-PSHNLSLV-FEFVPMLWGLPSGDaPDWTDAVQMA---GTVNILGFNEPDLTYsgSSNLLPA 119
                     5555555555677788889*************8.77888776.9***********9989999999999...9999*********8778******* PP

  Glyco_hydro_cc  89 eAaklwkqliqplrekgvklvsPavaatns......eegle.....WldeFleacskdckvdflavHwY.......kgd.feelkehieelheay 164
                     +Aa+ ++++++ lr ++v+++ P v ++n       +   +     W++ F+ +c+ dc++df ++HwY       +++ ++ +++++++++++ 
      EEA19974.1 120 AAAQRYITYMERLR-STVRIGVPNVLWNNYdstssgG---DyssrvWTSYFMGNCT-DCHFDFACIHWYqdcepgnSESgADWFTSNVTDAYNTL 209
                     ************54.79**********9998885542...345678**********.****************9974445899************ PP

  Glyco_hydro_cc 165 nkpiWvTEfalqsesgdasqeetkeflnevlawldsqeyVeryawfgfrsevsnvgannaLldenG.eltelgsaY 239
                     ++p+W+TEf     ++ ++++++ +fl++v++wld q+yVerya+fg        +  ++Lld+ G +l+ +g+aY
      EEA19974.1 210 QLPLWITEF-----QCYGNDDQQVSFLQSVMPWLDTQDYVERYAYFG--------VFPDYLLDDAGdALSAAGHAY 272
                     *********.....699******************************........7789999999999****9998 PP

>> Glyco_hydro_72  Glucanosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   2.4     1e-05     0.092     191     257 ..     160     228 ..     149     238 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 1e-05
                     HHHHHHHTTBTT-..--S-EEEEE----..SS--HHHHSHHHH.HHHHTT-SS-EEEEEE---SSSS--- CS
  Glyco_hydro_72 191 rvelaeylaCgdeddkadffglnmyeWC..gkssfktsGyder.tkefenysiPlflseyGCnkvtprkf 257
                     rv  ++y+  + +d + df  +  y+ C  g+s+  +  ++++ t++++ +++Pl+++e+ C  + +++ 
      EEA19974.1 160 RVW-TSYFMGNCTDCHFDFACIHWYQDCepGNSESGADWFTSNvTDAYNTLQLPLWITEFQCYGNDDQQV 228
                     544.46776666667*************7777877777786652688***************88877664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       353  (0.0196888); expected 358.6 (0.02)
Passed bias filter:                      273  (0.0152267); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1844.06
//
Query:       EEA19975.1  [L=241]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (241 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       323  (0.0180155); expected 358.6 (0.02)
Passed bias filter:                      297  (0.0165653); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.29s 00:00:00.72 Elapsed: 00:00:00.44
# Mc/sec: 1645.63
//
Query:       EEA19976.1  [L=314]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.5e-34  118.5   0.1    3.4e-34  118.0   0.1    1.1  1  adh_short     short chain dehydrogenase
    7.3e-24   84.6   0.0    1.1e-23   84.0   0.0    1.1  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
    1.7e-11   44.4   0.4    8.8e-10   38.8   0.4    2.2  1  KR            KR domain
    0.00025   20.6   0.1    0.00046   19.7   0.0    1.5  2  Epimerase     NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.0   0.1   7.6e-38   3.4e-34       2     189 ..      59     242 ..      58     246 .. 0.93

  Alignments for each domain:
  == domain 1  score: 118.0 bits;  conditional E-value: 7.6e-38
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCSHHH CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfselseee 100
                 ++l+tG+s+GIG a+a+ la++G +vvv+d  + +     +  k+    ++++++D+t+ +eve +  ++  ++g   ++v+NAGi + +p  e ++++
  EEA19976.1  59 IILITGGSNGIGAACAQMLASKGTQVVVLDVLPLTY----EAPKN----LHYYRCDLTNFDEVESVAVTVTREVGAPTCVVANAGICRGKPLLEATKRD 149
                 79**************************99985544....55555....89************************************************ PP

                 HHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGT....EEEEEEEESSBSSHHHHH CS
   adh_short 101 wervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptg....irvnavaPGlvdTdmake 189
                 +e ++ vN  g++++++++lp + +++ G+ v v+S++g+ + agv+ Y+A+Kaa  ++ + l+ el+       +r+++v P +v+T+m + 
  EEA19976.1 150 IELTFGVNSLGLLWTIKTFLPPLAEKNHGHFVIVASQTGHLATAGVVDYAATKAAALAIYEGLQTELRHVYkapaVRISCVSPSAVSTKMFTG 242
                 *******************************************************99999888888876544677***************875 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.0   0.0   2.4e-27   1.1e-23       3     185 ..      66     246 ..      64     255 .. 0.89

  Alignments for each domain:
  == domain 1  score: 84.0 bits;  conditional E-value: 2.4e-27
                   TTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSEEEE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHHHHH CS
  adh_short_C2   3 asgIGraiAkalaeeGaevvltdlneeakkrveelaeelgaevlecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreefdral 99 
                    +gIG+a+A+ la++G +vv+ d+         e  +  + ++++cD t+ ++ve+++ +v++++g   ++v nagi++   +p+le+++ +++ ++
    EEA19976.1  66 SNGIGAACAQMLASKGTQVVVLDVLPLTY----E--APKNLHYYRCDLTNFDEVESVAVTVTREVGAPTCVVANAGICRG--KPLLEATKRDIELTF 154
                   58*********************999872....2..2223457*************************************..*************** PP

                   HHHTHHHHHHHHHHHH.HCTSC.CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGG....GTEEEEEEEE--BHCTGGGGSTTH CS
  adh_short_C2 100 dvnlyslfllakaalp.lmkeg.gsivnlssvgaervvpnynaygaaKaalealtrylAvelgp....kgiRvNavspgpikTlaasgikgf 185
                    vn  +l+ ++k +lp l++++ g  v ++s  ++ ++++   y+a+Kaa  a+   l  el +      +R+ +vsp+++ T++ +gik  
    EEA19976.1 155 GVNSLGLLWTIKTFLPpLAEKNhGHFVIVASQTGHLATAGVVDYAATKAAALAIYEGLQTELRHvykaPAVRISCVSPSAVSTKMFTGIKLP 246
                   ****************8666667***************************99999988888765433368******************9854 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.8   0.4     2e-13   8.8e-10       3     158 ..      60     207 ..      59     230 .. 0.88

  Alignments for each domain:
  == domain 1  score: 38.8 bits;  conditional E-value: 2e-13
                 EEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT-- CS
          KR   3 ylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklleemt 101
                  litGG  g+G + a++la+kg + +vl                   +   + +++++D+++ d+ve++  ++++e ++ + v+  Ag+ r k+l e t
  EEA19976.1  60 ILITGGSNGIGAACAQMLASKGTQVVVLDVLP------------LTYEAPKNLHYYRCDLTNFDEVESVAVTVTREVGAPTCVVANAGICRGKPLLEAT 146
                 59********************9999984333............334445689************************9********************* PP

                 HHHHHHHHTTTTHHH.HHHHHHTTT...S--SEEEEEEEHHHHH--TT-HHHHHHHHHHHH CS
          KR 102 aedleqvlapKvkGa.wnLhelled...esldffvlfSSiagllgsagqanYaaaNaflDa 158
                 + d+e  +     G+ w ++++l++   ++  +fv+++S  g l +ag ++Yaa+ a   a
  EEA19976.1 147 KRDIELTFGVNSLGLlWTIKTFLPPlaeKNHGHFVIVASQTGHLATAGVVDYAATKAAALA 207
                 ************996488888887788899************************9876555 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.0     1e-07   0.00046       1      59 [.      60     116 ..      60     140 .. 0.83
   2 ?   -3.3   0.0       1.1   5.1e+03     141     154 ..     197     210 ..     186     219 .. 0.76

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 1e-07
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHCEEEE--TT-HHHHHHH CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledlelveldltdrsalerl 59 
                 il+tG++  iG+a ++ l++kg +v++ld l+     ++ ++l+ +++dlt+ +++e +
  EEA19976.1  60 ILITGGSNGIGAACAQMLASKGTQVVVLDVLPL--TYEAPKNLHYYRCDLTNFDEVESV 116
                 8******************************44..4445556699********999876 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 1.1
                 HHHHHHHHHHHHHH CS
   Epimerase 141 pYaaaKlageklve 154
                  Yaa+K+a+  + e
  EEA19976.1 197 DYAATKAAALAIYE 210
                 69999999887766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (314 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       408  (0.0227564); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.30s 00:00:00.84 Elapsed: 00:00:00.48
# Mc/sec: 1972.83
//
Query:       EEA19977.1  [L=542]
Description: cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-75  254.1   0.0      3e-75  253.7   0.0    1.1  1  p450      Cytochrome P450
  ------ inclusion threshold ------
       0.13   11.2   0.0       0.24   10.3   0.0    1.5  1  SDH_sah   Serine dehydrogenase proteinase


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  253.7   0.0   3.4e-79     3e-75      40     456 ..     102     529 ..      61     536 .. 0.84

  Alignments for each domain:
  == domain 1  score: 253.7 bits;  conditional E-value: 3.4e-79
                 EETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHHHHHHHHHTSHSTTTHHHHHHHHHHHHHHHHHCCCCHCS. CS
        p450  40 klgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkklRrfltptltsfgklsleelveeeaedlveklrkkagess. 137
                  + +k+v ++++p+a  evl++k+ +fs+ ++   l++  ++ +g g++ a+ge++kk+R++l+p++++   + l +++ e +  l ++l+++ + s+ 
  EEA19977.1 102 MMFNKEVLFVTSPKALSEVLVQKNYDFSKPYK---LRQGLGRILGIGLIIAEGEEHKKQRKLLMPAFLHRHVKDLYPIFWEKSTSLAAELEQNIKRSGq 197
                 455799******************99999644...55556799*************************995558*****************99999988 PP

                 ...EEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHH......HHHCHHHHCCCCCH.HHTCCSCHHHHHHHHHHHHHHHHHHHHHHH CS
        p450 138 ...elditellskaaldvigsilFgarfdlledeklselvkaveelss......llskssvqllllfp.llkylptkllrklkeavkklkdlldkliee 226
                    ++d++++l++ +ld++g   +g++fd+l ++++ e+v+a + +++      l   ++  ++  ++ ++  l  k    + +a+++l d+ ++li++
  EEA19977.1 198 ssqVFDVADWLARTTLDILGAAGLGREFDTLHNPDN-EIVRAYRGVFEqkppkgL---FRILMFIAKQqIINLLNIKRSDSIGAATEVLTDVSRRLIKD 292
                 899****************************99965.999999999986553321...34444444556777777777778888888888888888888 PP

                 HHHCHCHC......SCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHCCTTT.......T CS
        p450 227 rretldsa......kksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklreEidevlgdkr.......e 312
                 +r++  ++       + rrd l++ l++      + +++d+ l + +l++l+aG++Tt++ ++wa+y L  +P+vq++lreE++ +l+          +
  EEA19977.1 293 KRDEKVQDskdsvdRSVRRDILSVALDS------G-NFTDNMLENHLLTFLAAGHETTATSMTWAIYALCLYPHVQQRLREEVRATLPVGTmrgantvP 384
                 8877777745544444666666666666......3.8*************************************************944444699**** PP

                 -HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEETTEEE-TT-EEEEEHHHHHT-TTTS.SSTTS--GGGGB-TTS...CTESSCTT--TTEE CS
        p450 313 ptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirgylipkGtevivnlyalhrdpevf.pnPeeFdpeRFldekg...nskrksfaflPFGa 407
                 +t + + +lpyl av++E +R +p++  l+ R++ kd++i + +ipkGt++ +++ al+ ++e++ +n+  Fdp+R+ + ++        +f+f+ F  
  EEA19977.1 385 ITAELIDSLPYLHAVCNELFRVYPPAG-LTRRVAVKDTSILDQHIPKGTVIAISMRALNISKELWgENAFAFDPDRWMKPNQansGGGLTNFSFMTFLH 482
                 ***************************.999**************************************************9887445899******** PP

                 GGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGEEESSCSSEEES CS
        p450 408 GpRnCiGerlArmelklflatlLqnFevelqpetdpppileksglllpp 456
                 GpR+CiG+++Ar e   +la l+ +Fe+el  +t+ +   e+ gl+ +p
  EEA19977.1 483 GPRSCIGQGFARGEFACLLAALVGTFEMELE-DTTSELVIET-GLTSRP 529
                 *****************************95.5555555554.355444 PP

>> SDH_sah  Serine dehydrogenase proteinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   2.7e-05      0.24     165     229 ..     261     326 ..     253     375 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 2.7e-05
     SDH_sah 165 asilkvvekkeakdiddktliladiakkaikqveefvyellkdkydeekakei.akklteGrwthd 229
                   i++ ++ k ++ i   t +l+d++++ ik+ ++  ++  kd +d    ++i +  l +G++t +
  EEA19977.1 261 QQIINLLNIKRSDSIGAATEVLTDVSRRLIKDKRDEKVQDSKDSVDRSVRRDIlSVALDSGNFTDN 326
                 679999999**************************************9999873678999*99965 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (542 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       547  (0.0305092); expected 358.6 (0.02)
Passed bias filter:                      410  (0.022868); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.29s 00:00:00.85 Elapsed: 00:00:00.43
# Mc/sec: 3750.95
//
Query:       EEA19978.1  [L=501]
Description: cytochrome P450 monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-72  244.8   0.0    1.9e-72  244.5   0.0    1.0  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  244.5   0.0   1.1e-76   1.9e-72      12     448 ..      57     479 ..      44     492 .. 0.87

  Alignments for each domain:
  == domain 1  score: 244.5 bits;  conditional E-value: 1.1e-76
                 CHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHHHHHHHHHTSHS CS
        p450  12 nllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkklRrfltptltsfg 110
                   +ql  ++ +  ++++l+ kyg+i r+ + + ++   +g++a ke+++ ++  +++r +++  +t +    +  +++a+++++ +lR++l +++ ++ 
  EEA19978.1  57 MKQQL--SGRFPFIVHELHLKYGEIIRIAPTELSF---TGADAWKEIYGFRNGLPENR-KDPGENT-DADKSHPTIINADRKTHGSLRKLLSNAFSDK- 147
                 33333..36677789************99877654...6799***************9.6677666.67899999***********************. PP

                 TT.THHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHH.HHHCHHHHCCCCCH.HHTCCSCHHH CS
        p450 111 kl.sleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelss.llskssvqllllfp.llkylptkll 206
                  l   e+++  +++ lv +l++ a++ + +di+++++++++d+ig ++F ++fd+l++++   +  ++ ++++ ++  +  + l+ f  + ++++  + 
  EEA19978.1 148 VLkGQEPVLLHYIDLLVSRLQEVADKEEPVDIVRWFNYVTFDIIGHLAFYEPFDCLKNND---YHPWMSMIFNaIVYVHYIRTLQRFIdIRSIILAIMP 243
                 77789*************************************************999996...455555555544444555666666656667777777 PP

                 HHHHHHHHHHHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHH CS
        p450 207 rklkeavkklkdlldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklreEide 305
                 +++ e +k  ++l++++++ r+    +      df+++ll+a+  +kg+  l+  +l+a++  + +aG++Tt++ ls ++y+L ++P v++kl  E++ 
  EEA19978.1 244 KRIVERRKWHIGLVEEKVKRRKTHHPDY----IDFMSHLLQAE--EKGH--LTLPDLVANANLMVIAGSETTATILSGTIYYLCTHPRVMQKLLDEVRG 334
                 7777777778999999988777666666....9*********6..6665..************************************************ PP

                 HCCTTTT-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS.CEEETTEEE-TT-EEEEEHHHHHT-TTTSSSTTS--GGGGB-TTS.CTESSCTT- CS
        p450 306 vlgdkreptyddlqklpyldavikEtLRlhpvvplllpRevtk.dvvirgylipkGtevivnlyalhrdpevfpnPeeFdpeRFldekg.nskrksfaf 402
                  +++++++ ++ +++l+y +avi E++Rl+p++  + pR ++     i g  +p +t + +  ya+ r+p  f++Pe + peR+lde+g  ++   +a 
  EEA19978.1 335 SFESSDQINIARISQLKYINAVIDESFRLYPPAAGSHPRITPPeGANILGQWLPGNTSMGMAQYAVFRSPYNFKDPEIYLPERWLDEEGpYKNDRREAL 433
                 **999**********************************997559********************************************95558999** PP

                 -TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGEEES CS
        p450 403 lPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdpppile 448
                  PF++GpRnCiG++lA  e++l+la++L nF++el pe + +p+++
  EEA19978.1 434 QPFSFGPRNCIGRNLANIEMRLILAKVLFNFDFELTPECANWPKDQ 479
                 ************************************9988888875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (501 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       458  (0.0255452); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.32s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 3227.82
//
Query:       EEA19979.1  [L=957]
Description: geranylgeranyl pyrophosphate synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.6e-64  216.3   0.0    7.7e-64  215.2   0.0    1.6  2  polyprenyl_synt  Polyprenyl synthetase
     0.0013   18.4   0.3      0.027   14.2   0.0    3.0  3  Prenyltrans      Prenyltransferase and squalene oxidase repea
  ------ inclusion threshold ------
       0.04   13.0   0.0       0.12   11.5   0.0    1.8  2  SQHop_cyclase_N  Squalene-hopene cyclase N-terminal domain


Domain annotation for each model (and alignments):
>> polyprenyl_synt  Polyprenyl synthetase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.0      0.82   4.9e+03     143     182 ..     198     237 ..     197     238 .. 0.70
   2 !  215.2   0.0   1.3e-67   7.7e-64       2     255 ..     667     907 ..     666     908 .. 0.96

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 0.82
                      HHHHHHHHTH.HHCHHHHHHHHHHTTHHHHHHHHHHHHHHH CS
  polyprenyl_synt 143 yleivkyKTa.ylfalpvalaallagasdeelealkdigle 182
                      ++++ ++K   + +a p   aa++ +  +++ +++++++++
       EEA19979.1 198 FNKVSHHKVNgSFMASPSSTAAYMMHS-TQWDDECEHYLRH 237
                      667888888856667777777777775.5556888888876 PP

  == domain 2  score: 215.2 bits;  conditional E-value: 1.3e-67
                      HHHHHHHHHHHHSSS--HHHHHHHHHHHHHSCGHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-SEETTEE-HHHCTCHHHHHHHHHHHHHHHH CS
  polyprenyl_synt   2 elleealeylveagGKrlRpllvllaaealkeeeeelekaavlawivellhaasLvhDDimDdsetRRGqpcahrlvGnklAindgdfllaraf 95 
                      e+l  +++yl + +GK++R+ l+  ++ +lk++e   +++ v+ ++v +lh+asL++DDi+D+s++RRGqp+ah+++G+++A+n+g++++++a+
       EEA19979.1 667 EILLGPFNYLESLPGKNMRSQLIQSFNTWLKVPE---RSLTVIIKVVSMLHTASLLIDDIQDQSILRRGQPVAHSIFGTAQAMNSGNYVYFLAL 757
                      5677899************************888...7999***************************************************** PP

                      HHHHHHHSTTHHHHHHHHHHHHHHHHHHHHHHHHTTTTTCCC.SHHHHHHHHHHHTHHHCHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHH CS
  polyprenyl_synt  96 ellaklfekslellelfsevllqtveGqlldleeekdddlskfsleeyleivkyKTaylfalpvalaallagasdeelealkdiglelGlaFQi 189
                      + ++kl  +++++++++   l+++++Gq+++l ++  d+l ++++e+yl++v +KT++lf l+v+l+++ a ++    +++  +++ lG++FQi
       EEA19979.1 758 REVQKL--QNPKAISIYVGSLVDLHRGQGMELFWR--DSLMCPTEEQYLDMVANKTGGLFCLAVQLMQAEATVQ----ADFIPLVRLLGIIFQI 843
                      ******..99**********************999..9*******************************99983....5799************ PP

                      HHHHHHHHS-HHHHSS-TSHHHHTT---HHHHHHHHCT-HHHHHHHHHHTTSSHHHHHHHHHHHHH CS
  polyprenyl_synt 190 qDDylDlfgdpevlgKpagtDiqegkctlpilkalelaspeqrkvlkeilgkkaekeedvkealel 255
                       DDyl+l +++++ +K +++D++egk+++pi++ ++ a+p +r +l +il++k+++++ +++al++
       EEA19979.1 844 CDDYLNLKSTAYADNKGLCEDLTEGKFSFPIIHSIR-ANPGNR-QLINILKQKPREDDIKRYALSY 907
                      ************************************.****98.9*********888888888776 PP

>> Prenyltrans  Prenyltransferase and squalene oxidase repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.0   4.5e-06     0.027       8      22 ..      57      71 ..      54      77 .. 0.90
   2 ?   -0.6   0.0      0.19   1.2e+03       3      12 ..     375     384 ..     373     385 .. 0.87
   3 ?   -0.8   0.0      0.22   1.3e+03      12      22 ..     448     458 ..     446     475 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 4.5e-06
                 HHHHHHSHTTS-BBS CS
  Prenyltrans  8 efLlscQnedGGwgg 22
                 e++ls+Q edGGw  
   EEA19979.1 57 EYILSHQLEDGGWEM 71
                 8************86 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.19
                  HHHHHHHHHH CS
  Prenyltrans   3 vekavefLls 12 
                  +eka++fL++
   EEA19979.1 375 IEKAIRFLYK 384
                  8*******87 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 0.22
                  HHSHTTS-BBS CS
  Prenyltrans  12 scQnedGGwgg 22 
                  + Q + G+wg+
   EEA19979.1 448 KDQKPGGSWGS 458
                  55779999996 PP

>> SQHop_cyclase_N  Squalene-hopene cyclase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   1.9e-05      0.12      34      70 ..      39      75 ..      24      90 .. 0.77
   2 ?   -3.8   0.0      0.89   5.3e+03      50      67 ..     442     459 ..     439     470 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 1.9e-05
  SQHop_cyclase_N 34 llreflgeddeeeeekiakylrsqqredGgWelypgg 70
                     ++ ++++e ++ +  ++ +y++s+q edGgWe+y  +
       EEA19979.1 39 MISKTVDEHKAWLFPECFEYILSHQLEDGGWEMYASE 75
                     445666888888999999***************9865 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 0.89
  SQHop_cyclase_N  50 iakylrsqqredGgWely 67 
                      i   +++ q++ G+W+  
       EEA19979.1 442 ISSTVLKDQKPGGSWGST 459
                      556678888888988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (957 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       527  (0.0293937); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.73u 0.30s 00:00:01.03 Elapsed: 00:00:00.47
# Mc/sec: 6060.25
//
Query:       EEA19980.1  [L=329]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.8e-51  174.0   0.0    1.5e-50  172.3   0.0    1.7  1  Y_phosphatase3  Tyrosine phosphatase family
    4.5e-05   23.1   0.0    0.00068   19.2   0.0    2.1  2  Y_phosphatase2  Tyrosine phosphatase family
    0.00052   19.6   0.0     0.0019   17.8   0.0    1.8  2  Y_phosphatase   Protein-tyrosine phosphatase
  ------ inclusion threshold ------
       0.16   11.0   0.0       0.21   10.5   0.0    1.1  1  RapA_C          RNA polymerase recycling family C-terminal
       0.19   12.1   0.0       0.35   11.2   0.0    1.5  1  DUF2492         Protein of unknown function (DUF2492)


Domain annotation for each model (and alignments):
>> Y_phosphatase3  Tyrosine phosphatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  172.3   0.0   4.3e-54   1.5e-50       3     230 ..      40     325 ..      38     327 .. 0.87

  Alignments for each domain:
  == domain 1  score: 172.3 bits;  conditional E-value: 4.3e-54
  Y_phosphatase3   3 legvsNfRDlGg.....................yptadgrk..vrpgvlyRsaelsklteadlakLad.lgirtviDLRspeErea...eap... 67 
                     ++gv NfR+lGg                       t +g++  +rpg+++Rsa+ s++++a++a+La+ l i+ ++D+Rs++E++    + p   
      EEA19980.1  40 VSGVANFRELGGypcdtvppapasngsphnaseA-TLQGSHssIRPGFIFRSAQPSQINPAGIATLAHeLSIQVIFDFRSQTEIQLvttHYPdsl 133
                     789**************************99852.44444446*************************9**************766654444665 PP

  Y_phosphatase3  68 ..legaryvhlpv...................eeaaeeekeeeeaeetlaelYrelle..sakkayrkvfealad.ee.pvlfHCtaGKDRTGvl 137
                       ++ ++++++pv                    +++++++++ ++ + +  +Y+++++  + + ++rk+ e++++  + p+lfHCt GKDRTGv+
      EEA19980.1 134 leIPCTTRYSVPVfnegdyspaslvkkygvspDPVTHSASSTSANPAGFVPAYEAIARsaAENGSFRKITEHIIQhPDqPILFHCTLGKDRTGVF 228
                     5544448888888999******99*999885425678888889999999*********5544589**********6448**************** PP

  Y_phosphatase3 138 aalllsllGvdeedivaDYlltneyleelrerlkakleeellaea...leellsvrpeyleaalda.ieekygsvegYlreelglseeeiealre 228
                     aalllsl+Gv+ e+iv+DY++t+e++ + re+l ++l ++ +a++   +e +++++pe+++++ld+ +++k+gs+++Y+ +++gl+e e+++l +
      EEA19980.1 229 AALLLSLCGVSTEKIVEDYAMTTEGFGAWREHLIKRLLQRKDAATrqdAEFIIASHPETMKSFLDDvVRAKFGSARNYFVQQCGLTEYEVDKLIH 323
                     ********************************9999988865555788999*************985799**********************988 PP

  Y_phosphatase3 229 rl 230
                      l
      EEA19980.1 324 TL 325
                     77 PP

>> Y_phosphatase2  Tyrosine phosphatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.0     0.053   1.9e+02      13      41 ..      86     114 ..      77     139 .. 0.68
   2 !   19.2   0.0   1.9e-07   0.00068      78     131 ..     198     251 ..     178     275 .. 0.89

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.053
                     TEEEESS--HHHHHHHHHCT-SEEEE-SS CS
  Y_phosphatase2  13 elyrssyprasnfsflksLkLktiislsp 41 
                      ++rs++p+++n   + +L     i+++ 
      EEA19980.1  86 FIFRSAQPSQINPAGIATLAHELSIQVIF 114
                     69*********977766665444444444 PP

  == domain 2  score: 19.2 bits;  conditional E-value: 1.9e-07
                     HHHHHHHHHH-GGG-SEEEE-SSSSSHHHHHHHHHHHHTTB-HHHHHHHHHHHH CS
  Y_phosphatase2  78 llkkalklllnkenypvllhckrGkhrtglvigclRklqkWslasilnEyrrFs 131
                     + +k+ + ++++  +p+l hc+ Gk rtg+  + l  l + s+ +i+++y + +
      EEA19980.1 198 SFRKITEHIIQHPDQPILFHCTLGKDRTGVFAALLLSLCGVSTEKIVEDYAMTT 251
                     56778889999***************************************8755 PP

>> Y_phosphatase  Protein-tyrosine phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   5.3e-07    0.0019     167     203 ..     208     244 ..     183     280 .. 0.78
   2 ?   -1.5   0.0      0.42   1.5e+03      39      58 ..     274     291 ..     270     300 .. 0.77

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 5.3e-07
                    STTSS-EEEECSSSSHHHHHHHHHHHHHHHHHHHSEE CS
  Y_phosphatase 167 eaksgpvvVhCsaGvgRtgtfvaldillqqleaeeev 203
                    ++ ++p++ hC  G  Rtg+f+al + l+ +++e+ v
     EEA19980.1 208 QHPDQPILFHCTLGKDRTGVFAALLLSLCGVSTEKIV 244
                    5679************************999998764 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.42
                    TEEEEEEEEE---GGGHHHH CS
  Y_phosphatase  39 kkekkyIatQgPlkstvedF 58 
                    +++ ++I++ +P  +t+++F
     EEA19980.1 274 RQDAEFIIASHP--ETMKSF 291
                    46899*******..788887 PP

>> RapA_C  RNA polymerase recycling family C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0     6e-05      0.21     141     199 ..     249     308 ..     239     318 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 6e-05
                 T--TT-S--S--EE-S-HHHHTTS-S---STTSTHHH.HHHHHHTT--SSSSB--S-S-S CS
      RapA_C 141 mlveafpglpedGltvTfdRetAlareDvqFltwehP.lvrgaldlilsselGnaavall 199
                 m +e f   +e  +   ++R+ A +r D++F+   hP  +++ ld +++ ++G+a   ++
  EEA19980.1 249 MTTEGFGAWREHLIKRLLQRKDAATRQDAEFIIASHPeTMKSFLDDVVRAKFGSARNYFV 308
                 666777777777777889*******************678999**********9976655 PP

>> DUF2492  Protein of unknown function (DUF2492)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   9.9e-05      0.35      11      55 ..     279     325 ..     260     327 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 9.9e-05
     DUF2492  11 lllasgesytkasLkeaieekFGeearFht..CsaedltadeLiefL 55 
                  ++as+ +  k+ L + +++kFG++  ++   C  ++ ++d+Li+ L
  EEA19980.1 279 FIIASHPETMKSFLDDVVRAKFGSARNYFVqqCGLTEYEVDKLIHTL 325
                 5778888889999***************9555************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (329 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       462  (0.0257683); expected 358.6 (0.02)
Passed bias filter:                      430  (0.0239835); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.48
# Mc/sec: 2058.97
//
Query:       EEA19981.1  [L=520]
Description: aldehyde dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-77  261.5   0.0    1.3e-77  261.2   0.0    1.0  1  Aldedh    Aldehyde dehydrogenase family


Domain annotation for each model (and alignments):
>> Aldedh  Aldehyde dehydrogenase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  261.2   0.0   7.5e-82   1.3e-77      22     462 .]       5     437 ..       2     437 .. 0.90

  Alignments for each domain:
  == domain 1  score: 261.2 bits;  conditional E-value: 7.5e-82
                 EEE-B-HHHHHHHHHHHHHHHHHHTTS-HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH---HHHHHH.HHHHHHHHHHHHHHHHHHHSEEE.....EEE CS
      Aldedh  22 kvpaataedvdaavaaAkeafkawaklpaeeRaeiLrkaadlleerkeelaeletletGkplaeara.eveeaidvlryyaelaeklegev.....lps 114
                 kv + taed+++   +  ++f++ ++ +++ R+  L+++  +le++++e+++++  +   +  e++  + + a + + y  +++++ + +      +  
  EEA19981.1   5 KVLHDTAEDIQNLHTNLVNTFESGKTKDLAWRKWQLKQLWWMLEDNEKEFTAAMKEDLNRSSIESMItDFAGARKDILYHLQHIDQWAADEplgdtFVA 103
                 56677889999999999999999999999999999**********************999999999889999999999999998885553323332333 PP

                 CTTEEEEEEEEE-SEEEEEE-SSSCCHHHHHHHHHHHHTT-EEEEEE-TTSHHHHHHHHHHHHHTTS-TTSEEE--SSTCCHHHHHHH-TTESEEEEES CS
      Aldedh 115 segklalvrrePlGvvgaItPWNfPlllaawklapalaaGNtvvlKPaeetplsalllaelfeeaglPkgvlnvvtgsgsevgealvehpevdkvsftG 213
                 ++ +la +r+ePlGvv++I +WNfPlll+++ l++a+ aG++ ++KP+e  p + +ll +l+ +  l+k ++ vv+g  +e+ + l    +++++ ftG
  EEA19981.1 104 KQLRLARIRKEPLGVVLIIGAWNFPLLLVLQPLIAAITAGCCAIIKPSELIPSCQALLKHLIPK-YLDKSAIGVVCGAVAETTSLLEL--RFNHIFFTG 199
                 48999***********************************************************.9***********99998888865..8******** PP

                 -HHHHHHHHHHHHCTTSEEEEEE---EEEEE-TTSHHHHHHHHHHHHHHGGGGTSTTSEEEEEEEHHHHHHHHHHHHHHHHT--BS-TTSTT-SB---S CS
      Aldedh 214 stevgrkiakaaaknlkrvtlElGGknplivledaDldkaveaivkgafgnaGQvCiaasrllvqesiydefveklveaakklkvgdpldedtdvGPli 312
                 s +vgr + +aaaknl+++tlElGG+ p+i++++a++d+a++ ++++ f+n+GQ+C +++ ++v  s+yd+f+e l+  ++++  g+  +  +d  +++
  EEA19981.1 200 SATVGRIVSAAAAKNLTPLTLELGGQCPAIICKSANIDRAAKCVAFSKFLNSGQICLSVNHVFVDPSVYDQFTECLKYWIQTFLNGQL-T--VD-TAIV 294
                 *********************************************************************************9977775.3..34.478* PP

                 SHHHHHHHHHHHHHHHHTTSEEEE-TTE.SB-SSSTTEE--EEEES-TTTSHHHHS---SSEEEEEEESSHHHHHHHHHSSSEESEEEEE-SBHHHHHH CS
      Aldedh 313 seaqlekvekyveeakeegaklllGgereeaglekgyfvePtvlanvtpdmriaqeEiFGPVlsvikfkdeeeaieiaNdteyGLaagvftkdleraer 411
                 ++++++++ +++ +++    ++ +Gg    +g+++   +ePtv+ +v+ +++++++EiFGP+ ++ik  d+  a  +  +    La ++f++d +++++
  EEA19981.1 295 NPSHFDRLLNLICNTEG---RIFYGG----TGNRETRRMEPTVVLDVDINDTLLRDEIFGPICPIIKS-DFRSAYIATKQKGHPLAMYIFSNDKSEVQE 385
                 ***********987655...9*****....688999******************************96.566676677788999*************** PP

                 HHHHS-SSEEEESSSST--TTT.SEB--CGGGEES-BSHHHHHHHTEEEEEE CS
      Aldedh 412 vaerleaGnvyiNdsttgaaea.lpfgGvkqSglGreggkegleeytevktv 462
                 v ++ + G v++Nd + +a  + +pfgGv+ Sg+G  +g++g++ +t+ +tv
  EEA19981.1 386 VLDNTNSGGVTVNDVILHAGFSgAPFGGVGSSGHGYYHGAYGFNSFTHFRTV 437
                 ***************655555458************************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (520 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       617  (0.0344135); expected 358.6 (0.02)
Passed bias filter:                      531  (0.0296168); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.49
# Mc/sec: 3218.58
//
Query:       EEA19982.1  [L=782]
Description: benzoate 4-monooxygenase cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.6e-46  157.5   0.0    6.4e-46  157.0   0.0    1.1  1  p450             Cytochrome P450
    1.3e-05   25.1   0.0    2.7e-05   24.1   0.0    1.4  1  Methyltransf_23  Methyltransferase domain
     0.0003   20.6   0.0     0.0011   18.8   0.0    1.8  1  Methyltransf_31  Methyltransferase domain
    0.00032   21.3   0.0     0.0015   19.2   0.0    2.2  2  Methyltransf_25  Methyltransferase domain


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  157.0   0.0   1.4e-49   6.4e-46      26     441 ..      70     484 ..      50     502 .. 0.81

  Alignments for each domain:
  == domain 1  score: 157.0 bits;  conditional E-value: 1.4e-49
                 HHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSST.TCGHHHHHHHHHHHHHHHTSHSTT.THHHHHHHHH CS
        p450  26 lrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvl.fangekwkklRrfltptltsfgkl.sleelveeea 122
                 ++ ++kkyg+++r+ +   ++v++++p  +  vl+ k+   + +  +a+++    p k ++++   n +k+ + Rr +  +   + +l  +e+ +++++
  EEA19982.1  70 HEVIHKKYGDVVRVGP---KTVFINDPAGIPVVLGFKDRLEKTDSVNAFMQ----PGKPTSIVgIRNEQKHASYRRPIQGAYSLS-SLkLYEPAIDDMI 160
                 6678********9865...589***************74444443333333....566555551556699999999999999999.5555********* PP

                 HHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHH......HHHCHHHHCCCCCHHHTCCSCHHHHHHHHHHHH CS
        p450 123 edlveklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelss......llskssvqllllfpllkylptkllrklkeavkk 215
                 ++l   +++k+ +++++++t++   + +d+i++i+Fga+++ l++ k+  +  ++++ ++      +l ++++ l+ +++    +    ++k+ke    
  EEA19982.1 161 NKLTSIFDEKCRSKTVINVTQWCHFFSYDTIMNITFGAPLGFLDNAKD--MYGLIANQVKhvayvrVL-TQWPGLDYVIRTNP-IV-VAFKKHKES--P 252
                 *****************************************9888874..333333332211111144.55666666655332.22.355666644..6 PP

                 HHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHCCTTTT-H CS
        p450 216 lkdlldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklreEidevlgdkrept 314
                 ++ ++ + i++  e+   ++  +r++l+++++ak+ + +   ++d++++  + +  +aG+   s +l  +L +La++P  q++l+eEi +  ++  +++
  EEA19982.1 253 FFRFAVQRIRQEVEKPTADEVPKRTLLQHFVDAKSRYPD--IVDDTQIRLYCATNSLAGSLSPSRVLDCVLSWLAQHPGEQDRLYEEIVKNTREF-PVS 348
                 7778888877777777777789***********944444..6*********************************************98888664.8** PP

                 HHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS.CEEETT.EEE-TT-EEEEEHHHHHT-TTTS.SSTTS--GGGGB-TTS........CTESSCTT- CS
        p450 315 yddlqklpyldavikEtLRlhpvvplllpRevtk.dvvirg.ylipkGtevivnlyalhrdpevf.pnPeeFdpeRFldekg........nskrksfaf 402
                  +d  ++pyl  vi+E  Rlh+  ++ ++R+v     ++++ ++ip+ +++ ++  ++    + f ++P++F+peR+ ++kg        +    + a 
  EEA19982.1 349 LEDTVNMPYLGGVIREGYRLHHGGDIAIERKVGPsGATLPDgRFIPAYYDIAMSSPSIRV-CSAFgEEPHVFKPERWMRAKGesdddwkaRRTYMDKAD 446
                 ********************************6548999988****************99.55555*******************99987444677899 PP

                 -TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTST CS
        p450 403 lPFGaGpRnCiGerlArmelklflatlLqnFevelqpet 441
                 l F+ G R+CiG+ + ++el+ ++a+++ +F++el  +t
  EEA19982.1 447 LTFSQGSRACIGKSFTHLELFKVVASVMGQFKLEL-AGT 484
                 **********************************8.444 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.0     6e-09   2.7e-05      19     124 ..     542     656 ..     519     686 .. 0.70

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 6e-09
  Methyltransf_23  19 k.lraggrvLdiGcGtGillevlren...gfsvtgvDlspeaveiaekakkaqkdqfdeqeaae..pqgkfdlIvlrevlehvpdpp...ellr 103
                      + ++++ rvLd G+++G++l  l+++    + ++g D+ +   +  +k++++  + +   + ++   q++fdl+++r++   ++dp     +++
       EEA19982.1 542 NfNQPNVRVLDCGTADGYWLYDLSKQldpSAALIGTDIGSFPLDSFPKPRNMTLSIHSYKDPWPasWQNSFDLVHMRFCVAGLKDPNearIAID 635
                      2367788****************9994433488888885433333334444444444333444333556****************885557899 PP

  Methyltransf_23 104 qiatllkpgGylllseplasl 124
                      ++  l+kpgG++ l +++ s+
       EEA19982.1 636 RLICLVKPGGWIQLVDSTLSS 656
                      9999********999986655 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.0   2.4e-07    0.0011       3     107 ..     546     647 ..     544     668 .. 0.82

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 2.4e-07
  Methyltransf_31   3 kglrvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielArenaqklgldnveFeqgdiee.leklledekfDlilsnevlnaladpdki.. 93 
                       ++rvlD+G++ G+ ++ l ++l p a ++G Di  + + +  +        n+++++ +  +  + +++ ++fDl++ +  ++ l+dp+++  
       EEA19982.1 546 PNVRVLDCGTADGYWLYDLSKQLDPSAALIGTDIGSFPLDSFPK------PRNMTLSIHSYKDpWPASWQ-NSFDLVHMRFCVAGLKDPNEAri 632
                      699************************************99988......689**********9996699.9****999866667777665411 PP

  Methyltransf_31  94 .leeiervlkpggil 107
                       + +++ ++kpgg +
       EEA19982.1 633 aIDRLICLVKPGGWI 647
                      155666666676655 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       3.5   1.6e+04      63      90 ..     315     339 ..     302     343 .. 0.69
   2 !   19.2   0.0   3.3e-07    0.0015       1      97 []     550     645 ..     550     645 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 3.5
                      TTEEEEEEESTGGGSSHHHHHHHHHHHH CS
  Methyltransf_25  63 gsfDlvvssgalhhlsdedlekalkeia 90 
                      +  D+v+s+ a +h    +++++++ei 
       EEA19982.1 315 RVLDCVLSWLA-QHPG--EQDRLYEEIV 339
                      56799999755.6644..4557777775 PP

  == domain 2  score: 19.2 bits;  conditional E-value: 3.3e-07
                      EEEET-TTSHHHHHHHCTS.TSSEEEEEESSHHHHHHHHHHHHHTTTTEEEEESBCCG.BSS.STTTEEEEEEEST.GGGSSHHHHHHHHHHHH CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrl.gkakvtgvDiseemleaareraeeeglnvefvqgdaed.lpf.edgsfDlvvssga.lhhlsdedlekalkeia 90 
                      vLd+G+  G ++ +l+k+l ++a ++g+Di +  l+   +       n+++  ++ +d +p   ++sfDlv+++++   + ++++++ a++++ 
       EEA19982.1 550 VLDCGTADGYWLYDLSKQLdPSAALIGTDIGSFPLDSFPKPR-----NMTLSIHSYKDpWPAsWQNSFDLVHMRFCvAGLKDPNEARIAIDRLI 638
                      9******************769**************999877.....7888888887767753678**********666677788899****** PP

                      HHEEEEE CS
  Methyltransf_25  91 rvLkpgG 97 
                       ++kpgG
       EEA19982.1 639 CLVKPGG 645
                      ******9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (782 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       414  (0.0230911); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.69u 0.29s 00:00:00.98 Elapsed: 00:00:00.48
# Mc/sec: 4917.34
//
Query:       EEA19983.1  [L=142]
Description: hypothetical protein PMAA_007500 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (142 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       175  (0.00976072); expected 358.6 (0.02)
Passed bias filter:                      172  (0.0095934); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.26s 00:00:00.64 Elapsed: 00:00:00.42
# Mc/sec: 1017.91
//
Query:       EEA19984.1  [L=197]
Description: hypothetical protein PMAA_007510 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (197 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       336  (0.0187406); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.28s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1313.34
//
Query:       EEA19985.1  [L=378]
Description: hypothetical protein PMAA_007520 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.1e-05   23.5   0.0      5e-05   22.3   0.0    1.6  2  Fungal_trans_2  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.3   0.0   2.8e-09     5e-05      61     131 ..      89     154 ..      50     183 .. 0.89
   2 ?   -2.2   0.0     0.074   1.3e+03     313     326 ..     310     323 ..     232     358 .. 0.58

  Alignments for each domain:
  == domain 1  score: 22.3 bits;  conditional E-value: 2.8e-09
  Fungal_trans_2  61 reakrykslalkelqealaelsstlsrnekykdiLaaiLllcsieissgdvsdwrvhLeaatsliksrggs 131
                      ea  y++++++ lq  ++ l+ +ls     + +++a+L    ++ +s +  +w +h+++  ++i++rggs
      EEA19985.1  89 PEAITYYTKSVRSLQGRIESLEDRLS-----EGVIVAVLEFAYYDFVSQNLPRWLIHMNGFHAIIARRGGS 154
                     67889*********************.....***************************************9 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.074
  Fungal_trans_2 313 lWplFiaGceavde 326
                     lW l ia+ +a  e
      EEA19985.1 310 LWVLAIAALAADGE 323
                     35555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (378 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       412  (0.0229795); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2558.76
//
Query:       EEA19986.1  [L=107]
Description: hypothetical protein PMAA_007530 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.1e-18   65.8   0.0    4.5e-18   65.7   0.0    1.0  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
    9.2e-09   35.0   0.0    1.3e-08   34.6   0.0    1.3  1  adh_short     short chain dehydrogenase


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.7   0.0     5e-22   4.5e-18     136     234 .]       4     105 ..       1     105 [. 0.93

  Alignments for each domain:
  == domain 1  score: 65.7 bits;  conditional E-value: 5e-22
                   TTTTHHHHHHHHHHHHHHHHHHHHGG.GTEEEEEEEE--BHCTGGGGSTTHHH..HHHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEE CS
  adh_short_C2 136 pnynaygaaKaalealtrylAvelgp.kgiRvNavspgpikTlaasgikgfde..lleelearaplgrlgtpeevaeaalfLasdeasyitGqtlvv 229
                   + yn+yg++Kaal  lt  +A e+g+ +gi+vN+v pg+++T++  + ++f++  +   ++     +r+ t+e++++ +l ++s++a++it q++ +
    EEA19986.1   4 AAYNVYGTSKAALDYLTAVWAGEFGKsRGITVNSVGPGLVETDIIPHDPEFRKvaVDPMVDLTRAAHRASTIEDIGDSVLLIVSEKARWITAQHVSA 100
                   679**********************999****************99999999844566778888899999*************************** PP

                   STTGG CS
  adh_short_C2 230 DgGlt 234
                    gG+t
    EEA19986.1 101 SGGIT 105
                   ***87 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.6   0.0   1.4e-12   1.3e-08     141     187 ..       1      48 [.       1      56 [. 0.91

  Alignments for each domain:
  == domain 1  score: 34.6 bits;  conditional E-value: 1.4e-12
                 SB-TTBHHHHHHHHHHHHHHHHHHHHHGGGT.EEEEEEEESSBSSHHH CS
   adh_short 141 vpvagvaaYsAsKaavagltrslakelaptg.irvnavaPGlvdTdma 187
                 +p+a + +Y++sKaa++ lt  +a e+ +++ i+vn+v PGlv+Td+ 
  EEA19986.1   1 MPLAAYNVYGTSKAALDYLTAVWAGEFGKSRgITVNSVGPGLVETDII 48 
                 678999*********************98877*************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (107 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       196  (0.010932); expected 358.6 (0.02)
Passed bias filter:                      178  (0.00992805); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.34u 0.26s 00:00:00.60 Elapsed: 00:00:00.39
# Mc/sec: 820.06
//
Query:       EEA19987.1  [L=768]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.5e-24   84.3   0.0    1.4e-23   83.4   0.0    1.5  1  DDE_1          DDE superfamily endonuclease
    6.9e-18   64.8   1.5    1.3e-17   63.9   1.5    1.4  1  adh_short      short chain dehydrogenase
    1.8e-16   60.4   0.9    4.1e-16   59.3   0.9    1.5  1  adh_short_C2   Enoyl-(Acyl carrier protein) reductase
    1.2e-08   34.8   0.3    4.1e-08   33.1   0.3    2.0  1  HTH_Tnp_Tc5    Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
      0.013   15.6   0.1       0.22   11.7   0.0    2.6  3  Pcc1           Transcription factor Pcc1
      0.071   12.1   1.6       0.11   11.4   1.6    1.2  1  Amidase        Amidase
       0.25   11.4   2.6       0.32   11.0   0.6    2.2  2  AdoHcyase_NAD  S-adenosyl-L-homocysteine hydrolase, NAD bindi


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.4   0.0   5.6e-27   1.4e-23       2     175 .]     340     515 ..     339     515 .. 0.89

  Alignments for each domain:
  == domain 1  score: 83.4 bits;  conditional E-value: 5.6e-27
       DDE_1   2 erltvllcanaagsekLkplvigkak..sprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrleaekrk..ilLlldssrshetvel.le 94 
                 +++ ++++++ a++  + p +i+ ak  +++ ++    ++++  + +  ++ +w+ ++++ +WL +vfdk ++++ ++   lL+ld+++sh t+ + + 
  EEA19987.1 340 REWITTIGCICANGTAISPALIYMAKsgNLQDSWLQDFNAEQHRCFFATSESGWTNNEVGFAWLvNVFDKETKSQASRgwRLLILDGHGSHVTMRFiEY 438
                 678999****************96652268889999999**********************************666652267**************999 PP

       DDE_1  95 selqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                 ++++ i l+++Pa+s+++lqPld+ ++s+l + Y +ql + +++  +        lt +d+++   ++w+  +++e+i saf
  EEA19987.1 439 CDKNRILLAIFPAHSTHTLQPLDVAIFSPLSTAYTEQL-RRFINDCQGFTR----LTKRDFFRLFWASWEaTFTSENILSAF 515
                 **********************************8765.556666655555....9**************99******9987 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.9   1.5   5.2e-21   1.3e-17       1     115 [.      11     131 ..      11     142 .. 0.90

  Alignments for each domain:
  == domain 1  score: 63.9 bits;  conditional E-value: 5.2e-21
                 SEEEEESTTS..HHHHHHHHHHHHTT-EEEE...EESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHH..SSESEEEE---SS--SS CS
   adh_short   1 kvvlvtGass..GIGraiakelakeGakvvv...vdrseekleevakelkeegakalaiqvDvtdreevealvekavkkl..gkldvLvnNAGitgsgp 92 
                 kv++vtG ++  GIG  ia +la++Ga v++    ++s +++e+va++++++g ka++i++ v  ++ ++alve   + +  +++d+LvnNAG+ + g+
  EEA19987.1  11 KVAIVTGSGRenGIGAGIAFALARNGAAVTInyvSESSTQRAEAVAQKIRDQGGKATVIRASVD-EQGAKALVEGTLEAFetDHVDILVNNAGVGHIGS 108
                 89****986444*****************986524566789999*****************996.8999*********99889**************** PP

                 GGGCSHHHHHHHHHHHTHHHHHH CS
   adh_short  93 fselseeewervievNltgvfll 115
                 + +++ e+++ ++evN+ g++ +
  EEA19987.1 109 TVDITPEQIRHTFEVNVYGPMFM 131
                 *******************9987 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.3   0.9   1.6e-19   4.1e-16       4     110 ..      22     132 ..      17     154 .. 0.86

  Alignments for each domain:
  == domain 1  score: 59.3 bits;  conditional E-value: 1.6e-19
                   TSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSE.....EEE--TTSHHHHHHHHHHHHHHH..SSEEEEEE-----EGCSS-GGGH-HH CS
  adh_short_C2   4 sgIGraiAkalaeeGaevvltdlneeakkrveelaeelgae.....vlecDVtdeeqvealveevvekf..gklDilvnnagiapklkgpfletsre 93 
                   +gIG++iA ala++Ga v + +++e++ +r+e++a+++  +     v+++ V de+  +alve + e f  +++Dilvnnag+ +   g++++++ e
    EEA19987.1  22 NGIGAGIAFALARNGAAVTINYVSESSTQRAEAVAQKIRDQggkatVIRASV-DEQGAKALVEGTLEAFetDHVDILVNNAGVGHI--GSTVDITPE 115
                   8**************************9899888888763322223588887.67779***********999**************..********* PP

                   HHHHHHHHHTHHHHHHH CS
  adh_short_C2  94 efdraldvnlyslflla 110
                   +++++++vn+y+ + + 
    EEA19987.1 116 QIRHTFEVNVYGPMFMK 132
                   *************9985 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.1   0.3   1.6e-11   4.1e-08       2      60 ..     206     255 ..     205     262 .. 0.91

  Alignments for each domain:
  == domain 1  score: 33.1 bits;  conditional E-value: 1.6e-11
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh 60 
                  +e+ + L++Wi+ql+erg p+t++++ + A+e+         + + ++k+W  r++k h
   EEA19987.1 206 KEQSRTLIKWINQLTERGLPPTNSMLENFAREI---------SGKEPGKNWASRWLKAH 255
                  68999****************************.........67889**********99 PP

>> Pcc1  Transcription factor Pcc1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   8.4e-05      0.22       4      50 ..     144     190 ..     141     205 .. 0.88
   2 ?    0.4   0.0      0.29   7.4e+02      49      66 ..     552     569 ..     549     570 .. 0.91
   3 ?   -3.3   0.1       4.1   1.1e+04      12      35 ..     703     729 ..     700     753 .. 0.59

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 8.4e-05
                 EEEE-SSHHHHHHHHHHHHHHCHC-TTECEEEEEEETTEEEEEEEES CS
        Pcc1   4 isvpfpterlAsialrtLqvDkelsplavkrslslegnvLqveykAt 50 
                 is    + +lA  alr+L++D++++ + v r++ ++++ L  +++  
  EEA19987.1 144 ISTNMASYELALEALRSLKPDEKPNISLVARTYGVNQSNLSKRFRGV 190
                 6667778899999********9999888***********99998875 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.29
                 ESSHHHHHHHHHHHHHHH CS
        Pcc1  49 AttnrmLRvavngflesl 66 
                 A++ r LR  v+g++e+l
  EEA19987.1 552 AEDWRRLRKLVQGVFEDL 569
                 9999************98 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 4.1
                 HHHHHHHHHHHHH..CHC-TTE.CEEE CS
        Pcc1  12 rlAsialrtLqvD..kelspla.vkrs 35 
                 +lA+ a   Lq D  + +s ++  k++
  EEA19987.1 703 ELAKLAHLQLQNDvlATPSAPKrAKKQ 729
                 677777777887755333333333333 PP

>> Amidase  Amidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   1.6   4.5e-05      0.11     309     396 ..     645     736 ..     617     759 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 4.5e-05
                 ---SS-SCCCCCCCHHHHCCS-HHHHHHHHHHHHHCSCCCCCCCHHHHHHHHH.HHHHHHHHHCCC...BSEEEEESSSSS--BCCCCCHHH CS
     Amidase 309 erlsetkvlsellpksraellgeevkrrielgnyalsaeasskyylkaqkvrr.llrrefakafee...lDvllsPtaptpaprlgekdkti 396
                 +  + ++  +++  k+ +++l+++ k + +    ++ +e++++ +++a++ +r   ++e+ak+ +     Dvl++P+ap+ a+++  k+ ++
  EEA19987.1 645 KDEQAAQEQARKDDKKLQQELTKQAKEQEKAERAQIRQEKQEQRLQEATEKQRlKDEQELAKLAHLqlqNDVLATPSAPKRAKKQVSKQVKV 736
                 2333344445666667777777777777777777777777777777777666656667777765557778*************998887655 PP

>> AdoHcyase_NAD  S-adenosyl-L-homocysteine hydrolase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.6   0.00013      0.32      20     110 ..       7     107 ..       2     126 .. 0.59
   2 ?   -1.8   0.1       1.1   2.9e+03      99     145 ..     697     750 ..     681     760 .. 0.51

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00013
                    --TTSEEEEE--SH...HHHHHHHHHHHCT-EEEEE-S-HHHHHHHHC.......TT-EE--HHHCTTT-SEEEE-SSSSSSB-HHHHCCS-TTEE CS
  AdoHcyase_NAD  20 llaGkvavvaGyGd...vGkGcaaslkglGarvivtevdPicalqaam.......eGfevvtleevvkkadivvtttGnkdiitlehlkkmkddai 105
                     laGkva+v+G G    +G G a +l   Ga v++  v   ++ +a         +G + + +   v++      + G+ +  +++h++ + ++a 
     EEA19987.1   7 SLAGKVAIVTGSGRengIGAGIAFALARNGAAVTINYVSESSTQRAEAvaqkirdQGGKATVIRASVDEQGAKALVEGTLEAFETDHVDILVNNAG 102
                    48**********9544499***************99887665554443000111123333334444444333344444444444444444444444 PP

                    EEE-S CS
  AdoHcyase_NAD 106 vcniG 110
                    v+ iG
     EEA19987.1 103 VGHIG 107
                    44444 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 1.1
                    CS-TTEEEEE-SSTTTTBTHHHHHTT.......T-EEEEEETTEEEEE-TTS-E CS
  AdoHcyase_NAD  99 kmkddaivcniGhfdseidvaalean.......alkkeevkpqvdrvtlkdgkk 145
                    ++kd+  ++ + h + + dv a  +          k+++vk+q +  t ++g  
     EEA19987.1 697 RLKDEQELAKLAHLQLQNDVLATPSApkrakkqVSKQVKVKAQPEAHTEDNGVV 750
                    555666666666666655554432221000000334445555555555555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (768 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2991  (0.166825); expected 358.6 (0.02)
Passed bias filter:                      878  (0.0489709); expected 358.6 (0.02)
Passed Vit filter:                       160  (0.00892409); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 1.00u 0.30s 00:00:01.30 Elapsed: 00:00:00.47
# Mc/sec: 4952.82
//
Query:       EEA19988.1  [L=415]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.7e-05   24.2   3.2      0.041   13.1   1.2    2.3  2  FAD_binding_3   FAD binding domain
    3.1e-05   24.1   0.5    8.7e-05   22.7   0.5    1.8  1  NAD_binding_8   NAD(P)-binding Rossmann-like domain
    0.00035   20.3   0.7    0.00064   19.4   0.7    1.4  1  DAO             FAD dependent oxidoreductase
    0.00061   19.1   1.0     0.0011   18.2   0.7    1.4  1  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    0.00073   19.5   0.3     0.0032   17.4   0.3    2.1  2  NAD_binding_9   FAD-NAD(P)-binding
  ------ inclusion threshold ------
      0.012   14.3   0.4       0.02   13.6   0.4    1.3  1  HI0933_like     HI0933-like protein
      0.022   13.6   0.9      0.065   12.1   0.5    1.9  2  Trp_halogenase  Tryptophan halogenase
      0.041   14.5   0.5      0.086   13.4   0.5    1.5  1  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
      0.043   13.1   0.2      0.073   12.3   0.2    1.3  1  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.1   1.2   2.1e-05     0.041       3      62 ..      11      73 ..       9     129 .. 0.74
   2 !   11.1   0.0   8.7e-05      0.17     155     315 ..     130     304 ..     120     318 .. 0.56

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2.1e-05
                   EEEEE--SHHHHHHHHHHHH...TTHHEEEEESSSSSCCSSS--EEEHHHHHHHHHTT-HHHH CS
  FAD_binding_3  3 dVlIVGaGpaGlmlallLse...aGvrvvlvekrsttvvlpradglnqrtmellrqlGledri 62
                    V+I+G+Gp Gl +a  Ls      v v++ ek ++  + + +  +   + ++l+ lG   ++
     EEA19988.1 11 RVAIIGGGPGGLATAIALSAlsnVQVHVTVYEKARELREIGAGLNIGYNSWRVLELLGARSEV 73
                   79*************998751113355788888888777777777777777777777766555 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 8.7e-05
                    EEEEEE--GTT-HHHHHH....TGGEEEE...EEEEEEEEEEEEEEC.-SCCCTTC...CEEEEECCTTEE........EEEECCE.TEEEEEEEE CS
  FAD_binding_3 155 akYlvGaDGgrStvrktl....giefege...etvyeagvldvlfda.dlsdivep...lvlilsaesrgv........mviPlen.tlerfyvqv 230
                    a+ +vG DG rS vr+t+     i+f+g+   +t+++  +++ l d    ++++++   +v                  + iP ++  +  + ++v
     EEA19988.1 130 ADLVVGGDGIRSVVRQTAfpdhNIKFTGTtiwRTLVPRSFISHLTDIpTCTSWWHGtagHV---------YfspvddpsERIPENQdVEISARFLV 216
                    899*************973322344444411123333344444444434444444455422.........22333333378888887666666666 PP

                    ECCE-GGGS...CCCHHHHHH...HHHHHHHHTTSSCEE.EEEEEEEEEEEEEEESSSEE.TTEEE-GGGTEEE-STTSHHHHHHHHHHHHHH CS
  FAD_binding_3 231 earaekeer...sekfteeev...karlreivgektldv.eieevsawtvaqrvaekyrk.grvflaGDAaHihpPtgGqGlNtaiqDavnLa 315
                    + +++ ++r     ++t+e+v    +++++ v e+  +v + ++++    a    +k++  +++ l+GDA      + G G   a++D   La
     EEA19988.1 217 DPETDTAKRwnwGVDTTNENVeahFTNYDARVREALSHVpKGSWKEFSAFAGPRLNKLHAwNKLVLIGDAS-----AFGSGAAFAMEDGWILA 304
                    66555555445644555544400044556666666666655666666666666666666525888888884.....45666666666655555 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   0.5   4.4e-08   8.7e-05       1      30 [.      14      46 ..      14      54 .. 0.90

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 4.4e-08
                   EE--SHHHHHHHHHHHCC...TEEEEEE-SSSS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLaka...gfdvlllekrdr 30
                   I+G+G +Gl++A +L+     +++v+++ek++ 
     EEA19988.1 14 IIGGGPGGLATAIALSALsnvQVHVTVYEKARE 46
                   9**************99555788*******976 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.7   3.2e-07   0.00064       1      33 [.      11      48 ..      11      66 .. 0.88

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 3.2e-07
                EEEEECTSHHHHHHHHHHHHTT.....EEEEESSSSTT CS
         DAO  1 dvviiGGGiiGlstAyeLarrg.....Vtllekgdiag 33
                +v+iiGGG  Gl+tA +L++       Vt++ek++++ 
  EEA19988.1 11 RVAIIGGGPGGLATAIALSALSnvqvhVTVYEKARELR 48
                59****************877558899******98865 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.7   5.8e-07    0.0011       2      32 ..      11      44 ..      10      57 .. 0.83

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 5.8e-07
                 SEEEE--SHHHHHHHHHHHH...HTS-EEEEETT CS
                 xxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxx RF
  Pyr_redox_2  2 dvvviGgGpAGlaaaltlaq...agakvtlvele 32
                 +v++iGgGp+Gla+a+ l++    ++ vt++e+ 
   EEA19988.1 11 RVAIIGGGPGGLATAIALSAlsnVQVHVTVYEKA 44
                 79******************85448888888744 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.3   1.6e-06    0.0032       1      35 [.      13      45 ..      13      53 .. 0.90
   2 ?   -3.4   0.0       4.2   8.3e+03     119     150 ..     102     134 ..      88     134 .. 0.66

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 1.6e-06
  NAD_binding_9  1 aivGaGprGlavlerLlarakkkspleitlfdpse 35
                   ai+G+Gp Gla++ +L a +    ++++t+++++ 
     EEA19988.1 13 AIIGGGPGGLATAIALSALS--NVQVHVTVYEKAR 45
                   8******************7..**********954 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 4.2
  NAD_binding_9 119 vhraevvdleeradgq.avlladgaslaadaVv 150
                     +r+e v +e+ ++g   +  +dg++  ad Vv
     EEA19988.1 102 QLRKELVLIENVPEGGaNLNFSDGTEAFADLVV 134
                    456677777777777526666888888888886 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.4     1e-05      0.02       2      35 ..      11      47 ..      10      54 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 1e-05
                 SEEEE--SHHHHHHHHHH...HHTT--EEEE-SSSSS CS
  HI0933_like  2 dviviGgGaAGlmaAisa...akrgkrVlllekakkl 35
                 +v++iGgG+ Gl +Ai++   ++ + +V+++eka++l
   EEA19988.1 11 RVAIIGGGPGGLATAIALsalSNVQVHVTVYEKAREL 47
                 699************9986567788999****99875 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.5   3.2e-05     0.065       1      34 [.      11      44 ..      11      55 .. 0.87
   2 ?   -1.9   0.0      0.56   1.1e+03     189     218 ..     119     148 ..     108     158 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 3.2e-05
                    EEEEE--SHHHHHHHHHHHHHTTTSSEEEEEE-S CS
  Trp_halogenase  1 kivivGGGtaGwlaAaalakalkgklevtlvese 34
                    ++ i+GGG+ G  +A+al+   + +++vt+ e++
      EEA19988.1 11 RVAIIGGGPGGLATAIALSALSNVQVHVTVYEKA 44
                    699*******************999*****9986 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.56
                     EEEETTS-EEE-SEEEE-SGGG-IIIIIIT CS
  Trp_halogenase 189 slrledgreveadlfiDcsGfrgllieqaL 218
                     +l+ +dg+e  adl++   G r+ + + a+
      EEA19988.1 119 NLNFSDGTEAFADLVVGGDGIRSVVRQTAF 148
                     78899*****************99888776 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.5   4.3e-05     0.086       1      35 [.      11      48 ..      11      56 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 4.3e-05
                EEEEECSSHHHHHHHHHHHHTT...SEEEEEESSSSSS CS
   Pyr_redox  1 kvvvvGgGyiglElAgalaelg...kkVtvversdkll 35
                +v+++GgG  gl  A al++l     +Vtv e + +l+
  EEA19988.1 11 RVAIIGGGPGGLATAIALSALSnvqVHVTVYEKARELR 48
                79****************77764447999999888887 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.2   3.7e-05     0.073       2      21 ..      14      33 ..      13      48 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 3.7e-05
  Pyr_redox_3  2 IiGaGPaGlaaaielkkagl 21
                 IiG+GP Gla+ai+l  +  
   EEA19988.1 14 IIGGGPGGLATAIALSALSN 33
                 9************9987544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (415 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       581  (0.0324056); expected 358.6 (0.02)
Passed bias filter:                      525  (0.0292822); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 2843.55
//
Query:       EEA19989.1  [L=73]
Description: hypothetical protein PMAA_007560 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (73 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       240  (0.0133861); expected 358.6 (0.02)
Passed bias filter:                      220  (0.0122706); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.32u 0.24s 00:00:00.56 Elapsed: 00:00:00.38
# Mc/sec: 579.56
//
Query:       EEA19990.1  [L=1690]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.2e-11   41.8   0.0    1.6e-10   41.0   0.0    1.3  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    1.5e-07   31.6   0.3    5.6e-06   26.5   0.0    3.0  3  rve              Integrase core domain
    0.00022   21.0   0.2    0.00073   19.3   0.2    1.8  1  gag_pre-integrs  GAG-pre-integrase domain
  ------ inclusion threshold ------
       0.13   12.4   0.0       0.74   10.0   0.0    2.3  2  PAC4             Proteasome assembly chaperone 4
        0.8    9.9   8.7       0.46   10.6   0.1    3.6  3  Integrase_H2C2   Integrase zinc binding domain


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.0   0.0   4.5e-14   1.6e-10       7     178 ..    1200    1375 ..    1196    1432 .. 0.81

  Alignments for each domain:
  == domain 1  score: 41.0 bits;  conditional E-value: 4.5e-14
       RVT_2    7 slPkdrkaigsrWvftkkkddlkevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeee.lvvhqldvdsafLnae..ldeevyvkqP 100 
                  + P + +  g r+v   k++  +++  k+rlv+q ++ k ++++  + +P i+ +s rL+l + + ++ +  +  dv  a+++++  l+ e y++ P
  EEA19990.1 1200 DIPLEARIYGFRFVDEVKNKGTDKAFEKSRLVVQAYNDK-DKEFVLTQSPTIQRSSQRLILCIGTSKDgVRFWIRDVTQAYIQSTtkLNREFYIRIP 1295
                  568889999*********9999**************987.567999*****************876651556677*******987336788****** PP

       RVT_2  101 pGfeidreeekvykLnkslyGlkqapllWnekidk.vLkklgferseaesGly.vrgtgegklivalyvddlliagsdik 178 
                  p         +  ++ + lyG+  a+  W+++ ++   ++lg+e s+    l  +    +g  ++++  dd li++++  
  EEA19990.1 1296 PELRHYFPGCEFLRVVRPLYGIPEAGNHWFRTYHEhHTTHLGMETSTYDPCLLhCCDPKQGFGVIGMQTDDTLIVADEAF 1375
                  ****99888999*****************99886615678899999998876515555666689**********998764 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0       2.3   8.4e+03      71      98 ..     490     521 ..     486     524 .. 0.80
   2 ?    1.5   0.0     0.092   3.3e+02      30      91 ..     749     816 ..     745     821 .. 0.76
   3 !   26.5   0.0   1.6e-09   5.6e-06       7     117 ..     838     941 ..     833     943 .. 0.78

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 2.3
         rve  71 lsDngseytsk....afrefladlgirvsftr 98 
                 ++D  ++ +      a+ +f++++  ++++ r
  EEA19990.1 490 HTDEERTAARArykpAWDKFIQQYEGTPDMER 521
                 6777776664478899********99998877 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.092
         rve  30 vddfsrlilaealsdemdastvlalleravarfggve.......pervlsDngseytskafrefladlg 91 
                 + d+s + ++ +  de++  +++  l+r  +rfg+          +r  +D  +e++ +++ +f+++ +
  EEA19990.1 749 IWDYSLMSYITQSFDEDQCFLTATELRRLHRRFGHPSvgrlhktLLRAGYDTNPEMI-EKINRFCHHCQ 816
                 679999**********55555555555555566655599999888889999999999.88888888865 PP

  == domain 3  score: 26.5 bits;  conditional E-value: 1.6e-09
         rve   7 lwqvDvtvvripdgggkayllvvvddfsrlilaealsdem..dastvlalleravarfggvepervlsDngseytskafrefladlgirvsftrpgrpq 103
                  + vD+++++    g  + +l++vd ++r+  a+ l + +  ++ ++l++l+  ++ + g  p+ +++D g+ ++sk+f+ ++++lg+     ++   +
  EEA19990.1 838 SIIVDIMYIN----G--KPVLHIVDEATRFNAACWLISISarATWDALRMLW--IDTYLGP-PDFIVTDAGKNFVSKEFTHLASSLGTITVSVPVEAHW 927
                 5667888888....3..5688999**99997666555552004444444444..6666666.**************************999999999** PP

         rve 104 dnGkvErfhrtlkd 117
                 + G vEr h  l++
  EEA19990.1 928 SIGAVERYHAVLRR 941
                 *********99987 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.2     2e-07   0.00073      22      63 ..     772     816 ..     756     817 .. 0.76

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 2e-07
  gag_pre-integrs  22 ssinlWHrRLGHpsfsrlkkLfkkgllpglki..sk.sevCeaCq 63 
                      +++++ HrR+GHps++rl+k   +   + +++  +k +++C++Cq
       EEA19990.1 772 TELRRLHRRFGHPSVGRLHKTLLRAGYDTNPEmiEKiNRFCHHCQ 816
                      678899************9988544444444333555889****9 PP

>> PAC4  Proteasome assembly chaperone 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0       4.6   1.7e+04      27      42 ..     356     371 ..     338     383 .. 0.66
   2 ?   10.0   0.0   0.00021      0.74      32      70 ..     535     575 ..     512     578 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 4.6
        PAC4  27 plgslvvAmpsrtnkk 42 
                 +l++l +++p+  + +
  EEA19990.1 356 KLQDLFYCLPDELQTQ 371
                 5799999999988733 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00021
        PAC4  32 vvAmpsrtnkktptisTtLlgdg.sde..aserlAqrLArRl 70 
                  +++p+rt+ + pt++T  ++   +d   +s++lA+ LA R 
  EEA19990.1 535 QYSLPDRTK-NEPTTATGYFTVAaTDHneFSSSLASELANRS 575
                 69******9.7799999999777553355**********995 PP

>> Integrase_H2C2  Integrase zinc binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.1       0.1   3.6e+02      25      42 ..     285     302 ..     283     304 .. 0.86
   2 ?   10.6   0.1   0.00013      0.46      10      53 ..     774     819 ..     769     822 .. 0.89
   3 ?   -0.1   1.0      0.28     1e+03      10      23 ..    1325    1339 ..    1319    1343 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.1
  Integrase_H2C2  25 tlerlrrryyWpgmrkdv 42 
                     +l+ ++  yyW ++++ +
      EEA19990.1 285 MLKDVALSYYWDNIDQWI 302
                     7889999*******9977 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00013
  Integrase_H2C2  10 lkeaHdsagHlGiektlerlrrryy..WpgmrkdvkkyvksCetCq 53 
                     l+++H   gH+++ +  ++l r  y   p m +++++++++C+t  
      EEA19990.1 774 LRRLHRRFGHPSVGRLHKTLLRAGYdtNPEMIEKINRFCHHCQTYG 819
                     899****************99999866799************9875 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.28
  Integrase_H2C2   10 lkeaHds.agHlGie 23  
                      ++ +H++ + HlG+e
      EEA19990.1 1325 FRTYHEHhTTHLGME 1339
                      799**********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1690 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       717  (0.0399911); expected 358.6 (0.02)
Passed bias filter:                      529  (0.0295053); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.91u 0.31s 00:00:01.22 Elapsed: 00:00:00.44
# Mc/sec: 11604.02
//
Query:       EEA19991.1  [L=373]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    0.00068   19.1   2.5    0.00068   19.1   2.5    1.8  2  DUF2353          Uncharacterized coiled-coil protein (DUF2353
     0.0022   18.2   4.9     0.0076   16.5   4.9    1.9  1  HALZ             Homeobox associated leucine zipper
     0.0029   17.3   0.7     0.0029   17.3   0.7    2.5  2  Retrotran_gag_2  gag-polypeptide of LTR copia-type
  ------ inclusion threshold ------
      0.021   15.1   8.2        0.2   11.9   0.2    2.6  3  Retrotrans_gag   Retrotransposon gag protein
      0.076   13.2   0.1       0.18   12.0   0.1    1.6  1  VP9              VP9 protein
       0.13   12.3   3.2        0.3   11.1   3.2    1.6  1  FtsL             Cell division protein FtsL
        0.2   11.5   2.0       0.43   10.4   0.5    2.3  2  DASH_Dam1        DASH complex subunit Dam1
       0.27   11.5   5.0        1.2    9.5   1.4    2.5  2  Spc24            Spc24 subunit of Ndc80
        0.3   11.2   2.9       0.67   10.0   2.9    1.5  1  DUF4337          Domain of unknown function (DUF4337)
       0.66   10.9  10.1       0.11   13.4   3.4    2.6  2  PRKG1_interact   cGMP-dependent protein kinase interacting do
       0.79    9.5   5.0        2.1    8.2   5.0    1.8  1  DivIC            Septum formation initiator
        1.1    9.0   8.1       0.75    9.5   4.0    2.2  2  TetR             Bacterial transcriptional repressor
        1.5    6.7   6.8      0.074   11.0   1.2    1.6  2  V_ATPase_I       V-type ATPase 116kDa subunit family
        2.7    8.7  11.6       0.59   10.8   6.3    2.3  2  HIP1_clath_bdg   Clathrin-binding domain of Huntingtin-intera
        5.2    7.1  14.4       0.33   11.0   6.2    2.1  2  UPF0242          Uncharacterised protein family (UPF0242) N-t
        5.5    6.9  10.1        6.7    6.7   3.5    3.6  4  Takusan          Takusan


Domain annotation for each model (and alignments):
>> DUF2353  Uncharacterized coiled-coil protein (DUF2353)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   2.5   6.1e-07   0.00068      51     170 ..      75     196 ..      42     201 .. 0.80
   2 ?   -2.6   0.9       2.4   2.7e+03     140     181 ..     259     301 ..     243     308 .. 0.75

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 6.1e-07
     DUF2353  51 akaadlkeekekekklsqlleesreenkalkleveeLrqklkeaqgDiklLReqlarqrlglk.dedlletrhssaeereelvkqlEklkekiqqlerd 148
                    ++ +e+  ++ +l + +   + e k+ ++++e+L+++ +e++ D +++R  +ar +l+++ + ++++++  +a +r     +l k  +     e  
  EEA19991.1  75 ILYQEHEEDLAEKDDLKEEFDALKAEHKKVRKNMEQLQSQHQELEADRDMFRDAFARVQLRVSiEPGTAGATANHATDRTPKSTKLPKGSKLSDGAEPT 173
                 333344556888999999999999999999999999999999999999999999999888776245778888888999999999999999999999999 PP

     DUF2353 149 lka.vldekeelvterdaykeKa 170
                 +++ ++d +  l  +rd+y +  
  EEA19991.1 174 FESwLIDMRASLDNNRDHYETPG 196
                 98735799999999999998755 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 2.4
     DUF2353 140 ekiqqlerdlkavldekeelvterdaykeK.aerLnqeLnviL 181
                 +k + ++ +l + +   ++ + e  ++k+  +++Ln e+++++
  EEA19991.1 259 KKDTRFQDFLADFTQLAQDSELEISSWKNElYRKLNFEMQHAV 301
                 5666777778888888888888888888872456999988876 PP

>> HALZ  Homeobox associated leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   4.9   6.7e-06    0.0076       9      40 ..      89     120 ..      86     122 .. 0.94

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 6.7e-06
        HALZ   9 vLKasYdaLksdydsLkkenekLkaelqeLke 40 
                  LK  +daLk+++  ++k  e+L+++ qeL +
  EEA19991.1  89 DLKEEFDALKAEHKKVRKNMEQLQSQHQELEA 120
                 6*****************************86 PP

>> Retrotran_gag_2  gag-polypeptide of LTR copia-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.8      0.51   5.7e+02      42      80 ..      81     117 ..      66     130 .. 0.57
   2 !   17.3   0.7   2.6e-06    0.0029      28      80 ..     227     277 ..     224     289 .. 0.93

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.51
  Retrotran_gag_2  42 ekksaankltlrkklfslkmkegesvadhinkleelvne 80 
                      e++  a k  l++++ +lk + + +v++ +++l++  +e
       EEA19991.1  81 EED-LAEKDDLKEEFDALKAEHK-KVRKNMEQLQSQHQE 117
                      333.3555555555544443333.555555555554444 PP

  == domain 2  score: 17.3 bits;  conditional E-value: 2.6e-06
  Retrotran_gag_2  28 ktakevWdkLkelyekksaankltlrkklfslkmkegesvadhinkleelvne 80 
                      ++a +++++Lk+++   ++ nk+  + kl+ l+mk+++  +d+++++++l+++
       EEA19991.1 227 TDAEDMFEHLKTIFLDVNRVNKA--KDKLYILQMKKDTRFQDFLADFTQLAQD 277
                      5799**************99996..8************************987 PP

>> Retrotrans_gag  Retrotransposon gag protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   2.4     0.012        13      26      82 ..      67     121 ..      51     133 .. 0.81
   2 ?   11.9   0.2   0.00018       0.2       6      78 ..     205     279 ..     200     321 .. 0.75
   3 ?   -2.7   0.0       6.4   7.2e+03      27      54 ..     310     337 ..     297     338 .. 0.74

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.012
  Retrotrans_gag  26 sesWkdlkkaflktflpserkdqleeelsslrQgtesvreYvtrfktladqldevlt 82 
                     +++ k+++  ++++ ++ ++kd+l+ee+  l+ ++++vr+ ++++++  ++l+   +
      EEA19991.1  67 MHIMKQYRILYQEHEEDLAEKDDLKEEFDALKAEHKKVRKNMEQLQSQHQELE--AD 121
                     558889999999999****************************9999988887..44 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 0.00018
  Retrotrans_gag   6 slegaAkswlkslvarsida.sesWkdlkkaflktflpserkdqleeelsslrQ.gtesvreYvtrfktladqld 78 
                      +eg+A+++l +  +++  + ++  +d+ +++++ fl+ +r ++++++l  l+  ++  ++++++ f++la++ +
      EEA19991.1 205 MCEGRASKHLLPRMRDDSPNpFTDAEDMFEHLKTIFLDVNRVNKAKDKLYILQMkKDTRFQDFLADFTQLAQDSE 279
                     56778777776665555555544555555555555555555577777777777777***************9876 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 6.4
  Retrotrans_gag  27 esWkdlkkaflktflpserkdqleeels 54 
                     + W+ + +a  kt    e+ ++++++++
      EEA19991.1 310 MGWAAFVNACYKTANRLEQINLAKDRIQ 337
                     4588888888888888888888888776 PP

>> VP9  VP9 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.1   0.00016      0.18      14      72 ..     230     284 ..     226     289 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00016
         VP9  14 tekYEevlltfeavesvrkSelrdgvfiVrlkdkkvlklknGlkrLreLtgDntLkiel 72 
                  + +E++ + f  v++v k+  +d+++i ++k++    +++ l    +L +D+ L+i +
  EEA19991.1 230 EDMFEHLKTIFLDVNRVNKA--KDKLYILQMKKDTR--FQDFLADFTQLAQDSELEISS 284
                 6789999999*******997..8********99875..7899**************986 PP

>> FtsL  Cell division protein FtsL
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   3.2   0.00026       0.3      32      70 ..      68     106 ..      66     122 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00026
        FtsL  32 lithqtRqlvselekllserdkLeeewrnLlLEestlsa 70 
                 +i  q+R+l++e e+ l e+d+L+ee++ L+ E +++++
  EEA19991.1  68 HIMKQYRILYQEHEEDLAEKDDLKEEFDALKAEHKKVRK 106
                 67889****************************998776 PP

>> DASH_Dam1  DASH complex subunit Dam1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.5   0.00038      0.43       1      30 [.      90     119 ..      90     130 .. 0.91
   2 ?   -1.5   0.0       2.1   2.3e+03      17      34 ..     231     248 ..     226     260 .. 0.66

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00038
   DASH_Dam1   1 lepafaeLaDsletLdknledLqqihesLs 30 
                 l+++f  L+ + ++++kn+e+Lq+ h++L+
  EEA19991.1  90 LKEEFDALKAEHKKVRKNMEQLQSQHQELE 119
                 56899**********************997 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 2.1
   DASH_Dam1  17 knledLqqihesLsdfNe 34 
                 + +e+L+ i  +++++N+
  EEA19991.1 231 DMFEHLKTIFLDVNRVNK 248
                 557777777777777765 PP

>> Spc24  Spc24 subunit of Ndc80
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   1.4     0.001       1.2      12      48 ..      86     122 ..      67     138 .. 0.76
   2 ?    3.0   0.1      0.11   1.2e+02      26      70 ..     245     300 ..     225     338 .. 0.69

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.001
       Spc24  12 elsdleselesleselaelkeeleeleeeseekeser 48 
                 e +dl++e ++l++e ++ ++++e+l+++ +e e++r
  EEA19991.1  86 EKDDLKEEFDALKAEHKKVRKNMEQLQSQHQELEADR 122
                 5578888999999999999999999999988833322 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.11
       Spc24  26 elaelkeeleeleeesee.......keser...vedetl....lklklYrsLGielekd 70 
                 + ++ k++l  l++++         +       ++d+ l     k +lYr+L +e++  
  EEA19991.1 245 RVNKAKDKLYILQMKKDTrfqdflaD---FtqlAQDSELeissWKNELYRKLNFEMQHA 300
                 45666666666777666644444332...044344555566779999*****9998654 PP

>> DUF4337  Domain of unknown function (DUF4337)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   2.9    0.0006      0.67      67     125 ..      74     133 ..      61     140 .. 0.66

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.0006
     DUF4337  67 k..aeelaaavdkkiakykkkiarykkekkeikkkAkeleaerdeaneasdkfdlasalLq 125
                 +   +e++++  ++++++k++ +  k+e k+++k+ ++l+++ +e+++  d f  a a +q
  EEA19991.1  74 RilYQEHEEDL-AEKDDLKEEFDALKAEHKKVRKNMEQLQSQHQELEADRDMFRDAFARVQ 133
                 34334444444.5788888888888888888888888888888888888888865544444 PP

>> PRKG1_interact  cGMP-dependent protein kinase interacting domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   3.4    0.0001      0.11       2      50 ..      73     124 ..      72     139 .. 0.80
   2 ?    0.7   0.4      0.89     1e+03       4      49 ..     252     297 ..     250     343 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 0.0001
  PRKG1_interact   2 YkkLY...eeekeenerLkreLeelekelselkseleklkqqrqesvskrss 50 
                     Y+ LY   ee ++e++ Lk+e + l+ e +++++++e+l++q+qe  ++r  
      EEA19991.1  73 YRILYqehEEDLAEKDDLKEEFDALKAEHKKVRKNMEQLQSQHQELEADRDM 124
                     88888322345689**************************998886666654 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.89
  PRKG1_interact   4 kLYeeekeenerLkreLeelekelselkseleklkqqrqesvskrs 49 
                     kLY  + ++  r ++ L + ++  ++++ e+++ k++  ++++ + 
      EEA19991.1 252 KLYILQMKKDTRFQDFLADFTQLAQDSELEISSWKNELYRKLNFEM 297
                     7888889999999999999999999999999888866333333222 PP

>> DivIC  Septum formation initiator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   5.0    0.0019       2.1      18      64 ..      86     133 ..      72     139 .. 0.80

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0019
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC-XXXXXXX.XXXXXXX CS
       DivIC  18 aykqlkqeiaalqaelaklkaeneeLeaevkdLksdedyi.eerARse 64 
                    +lk+e +al+ae +k+++  e+L+++ ++L+ d+d+  ++ AR +
  EEA19991.1  86 EKDDLKEEFDALKAEHKKVRKNMEQLQSQHQELEADRDMFrDAFARVQ 133
                 567899999999999999999999999999999989998623456655 PP

>> TetR  Bacterial transcriptional repressor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   4.0   0.00067      0.75      27      87 ..      63     123 ..      43     137 .. 0.76
   2 ?    0.9   0.1      0.31   3.4e+02      53     121 ..     235     310 ..     217     317 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00067
                 HHHHHHHHHHTHHHHHSHHHHHHC-HHHHHHHHHHHHHHHHHHHHHHHHHHHTTSB---GH CS
        TetR  27 lealfelmwrYRFlyrDlaellsrnpeLakryrqlleelqaqlrellqelveagllqadde 87 
                  +  + +m +YR ly+  +e l++ ++L++++ +l +e+++  +++ q   + + l+ad +
  EEA19991.1  63 YRRQMHIMKQYRILYQEHEEDLAEKDDLKEEFDALKAEHKKVRKNMEQLQSQHQELEADRD 123
                 4667899*************************99988887655555554455566666665 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.31
                 HHHHHHHHHHHHHHHHHHHHHHHHHHTTSB---GHHHHHHHHHHHHHHHCHHHHHH.......HHSS-----HHCH CS
        TetR  53 eLakryrqlleelqaqlrellqelveagllqaddeeleaLadniwlvatyWlsfqr.......araeskalteaal 121
                 +L++ + ++++  +a+ +  + +++++  +q   +++++La+   l +++W ++++       ++a  k+ +e+ +
  EEA19991.1 235 HLKTIFLDVNRVNKAKDKLYILQMKKDTRFQDFLADFTQLAQDSELEISSWKNELYrklnfemQHAVMKEADEEGM 310
                 5666666666666666666667788888888778889999999999999999988876666655555555555555 PP

>> V_ATPase_I  V-type ATPase 116kDa subunit family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   1.2   6.6e-05     0.074      50     117 ..      66     133 ..      29     180 .. 0.78
   2 ?   -2.0   0.4      0.56   6.3e+02      11      60 ..     240     301 ..     224     355 .. 0.46

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 6.6e-05
  V_ATPase_I  50 ekavikeeeaeesleapeekeldeleeelekleeelkelnenleklkkelnelvelkavlekakefle 117
                 + +++k+ ++  ++++++ +e d+l+ee++ l++e k++++n+e+l+++++el+  + +++ a + ++
  EEA19991.1  66 QMHIMKQYRILYQEHEEDLAEKDDLKEEFDALKAEHKKVRKNMEQLQSQHQELEADRDMFRDAFARVQ 133
                 5566667777888899999999********************************99999887655554 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.56
  V_ATPase_I  11 frDlnedvnafqrkfvkevrrcdemerklrfleeeieklekavikeeea............e 60 
                 f D+n+  +a ++ ++ ++++    +  l  +++  ++ e ++ + +++            +
  EEA19991.1 240 FLDVNRVNKAKDKLYILQMKKDTRFQDFLADFTQLAQDSELEISSWKNElyrklnfemqhaV 301
                 44444444444444444444444444444444443333222222222213333333222221 PP

>> HIP1_clath_bdg  Clathrin-binding domain of Huntingtin-interacting protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   6.3   0.00053      0.59       6      67 ..      64     124 ..      62     139 .. 0.85
   2 ?    0.0   0.2       1.2   1.3e+03      16      47 ..     273     304 ..     246     338 .. 0.72

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00053
  HIP1_clath_bdg   6 rKnAevtkqlsvarqaqeeverekkeleeelerlkeeaerkleeqkeelekLkreleakrae 67 
                     r++  ++kq     q++ee  +ek++l+ee+++lk+e+ +k+++  e+l++ ++elea r+ 
      EEA19991.1  64 RRQMHIMKQYRILYQEHEEDLAEKDDLKEEFDALKAEH-KKVRKNMEQLQSQHQELEADRDM 124
                     6777899999************************9986.57888888999999999988765 PP

  == domain 2  score: 0.0 bits;  conditional E-value: 1.2
  HIP1_clath_bdg  16 svarqaqeeverekkeleeelerlkeeaerkl 47 
                     + a+ +  e+   k+el ++l+   ++a +k+
      EEA19991.1 273 QLAQDSELEISSWKNELYRKLNFEMQHAVMKE 304
                     34555555666667766666665555555554 PP

>> UPF0242  Uncharacterised protein family (UPF0242) N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   6.2   0.00029      0.33      81     138 ..      59     127 ..      11     135 .. 0.77
   2 ?    0.9   1.1      0.36   4.1e+02     125     170 ..     263     307 ..     227     310 .. 0.67

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00029
     UPF0242  81 d...........eglktkeealeelqeeeeeLkeeldakeeelerlkeenqqLqekleaiaedfeelkl 138
                             +++++  ++ ee  +e+++Lkee+da + e ++ +++ +qLq++ ++  +d ++++ 
  EEA19991.1  59 FdfvyrrqmhimKQYRILYQEHEEDLAEKDDLKEEFDALKAEHKKVRKNMEQLQSQHQELEADRDMFRD 127
                 155555555555667777889999999********************************9999999886 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.36
     UPF0242 125 kleaiaedfeelkleleeqLaekqellqeyqetieeqrsvlekrqd 170
                 + ++  +df +l +++e ++   ++ l   + ++e q++v+++ ++
  EEA19991.1 263 RFQDFLADFTQLAQDSELEISSWKNELYR-KLNFEMQHAVMKEADE 307
                 33444458999999998888876655533.4589999999988665 PP

>> Takusan  Takusan
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.1      0.82   9.1e+02      50      78 ..      63      91 ..      42      95 .. 0.69
   2 ?    6.7   3.5     0.006       6.7      56      83 ..      90     117 ..      71     119 .. 0.81
   3 ?    1.7   0.2      0.22   2.4e+02      29      29 ..     282     282 ..     219     306 .. 0.55
   4 ?    0.9   0.0      0.38   4.2e+02      31      49 ..     284     302 ..     280     333 .. 0.75

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.82
     Takusan 50 drpsvrlnpeyekLklqhekvMsdlqklq 78
                +r+ + +  +y +L  +he+ +++ ++l+
  EEA19991.1 63 YRRQMHIMKQYRILYQEHEEDLAEKDDLK 91
                44556666777777777777777766665 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.006
     Takusan  56 lnpeyekLklqhekvMsdlqklqneise 83 
                 l+ e+  Lk +h+kv   +++lq ++ e
  EEA19991.1  90 LKEEFDALKAEHKKVRKNMEQLQSQHQE 117
                 677999********************98 PP

  == domain 3  score: 1.7 bits;  conditional E-value: 0.22
     Takusan  29 i 29 
                 i
  EEA19991.1 282 I 282
                 2 PP

  == domain 4  score: 0.9 bits;  conditional E-value: 0.38
     Takusan  31 reRdELrdiLalytegsln 49 
                 + ++EL++ L++ ++  + 
  EEA19991.1 284 SWKNELYRKLNFEMQHAVM 302
                 4466666666666655544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (373 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1728  (0.0963802); expected 358.6 (0.02)
Passed bias filter:                      693  (0.0386525); expected 358.6 (0.02)
Passed Vit filter:                       135  (0.0075297); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              16  [number of targets reported over threshold]
# CPU time: 0.64u 0.27s 00:00:00.91 Elapsed: 00:00:00.44
# Mc/sec: 2528.27
//
Query:       EEA19992.1  [L=1336]
Description: retrovirus polyprotein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.2e-33  113.5   0.1    1.1e-32  112.4   0.1    1.6  1  RT_RNaseH       RNase H-like domain found in reverse transcri
    7.1e-33  112.6   0.0    1.6e-32  111.5   0.0    1.6  1  RT_RNaseH_2     RNase H-like domain found in reverse transcri
    8.9e-30  103.9   0.0    1.5e-29  103.1   0.0    1.4  1  RVT_1           Reverse transcriptase (RNA-dependent DNA poly
    3.4e-14   52.7   0.4    7.5e-14   51.6   0.4    1.6  1  Integrase_H2C2  Integrase zinc binding domain
    1.5e-13   51.0   0.0    3.4e-13   49.8   0.0    1.7  1  rve             Integrase core domain
  ------ inclusion threshold ------
      0.017   15.3   0.0      0.046   13.9   0.0    1.8  1  zf-H2C2         H2C2 zinc finger
      0.086   12.6   0.0       0.17   11.7   0.0    1.4  1  RVP_2           Retroviral aspartyl protease


Domain annotation for each model (and alignments):
>> RT_RNaseH  RNase H-like domain found in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.4   0.1   4.5e-36   1.1e-32       2     105 .]     563     670 ..     562     670 .. 0.94

  Alignments for each domain:
  == domain 1  score: 112.4 bits;  conditional E-value: 4.5e-36
                 TTS-EEEEEEECTEEEEEEEEEETTE..EEEEEEEEEE--HHHHTS-HHHHHHHHHHHHHHHHHHHHTS..--..EEEE-SS--TTTTT----.---HH CS
   RT_RNaseH   2 pskpfiletDAsddgigavLsqreedgeerpiafaSrklsgaernystiekellAivaalkkfrhylqg..rk..ftvitDhknlkyllskkslngrla 96 
                 p+ p+ letDAsd +++av sq ++dg+++p+a++Sr++++ae ny++++ke+lAiv alk++r  l g  r+  f++++Dh +l+y++++k+l++r+a
  EEA19992.1 563 PELPCRLETDASDGVVAAVFSQLQDDGQWHPVAYYSRTMNSAEFNYDIYDKEMLAIVDALKEWRAELIGlqREerFEILSDHLALQYFMTTKKLTSRQA 661
                 7899************************************************************99876642247************************ PP

                 HHHHHC-XX CS
   RT_RNaseH  97 rWaleLsey 105
                 rW++ L++y
  EEA19992.1 662 RWCELLNQY 670
                 *******99 PP

>> RT_RNaseH_2  RNase H-like domain found in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.5   0.0   6.3e-36   1.6e-32       1      95 [.     537     631 ..     537     639 .. 0.97

  Alignments for each domain:
  == domain 1  score: 111.5 bits;  conditional E-value: 6.3e-36
  RT_RNaseH_2   1 WteeqekafeklkealtsapvLahpdpdkpfiletDaSdtgigavLsqedddgkerpiafaSrklskaernysttekellAivwalkkfrhyllg 95 
                  Wt e+++afeklk+ l+sap+L h++p++p+ letDaSd  ++av sq +ddg+++p+a++Sr++++ae ny++++ke+lAiv alk++r  l g
   EEA19992.1 537 WTGECREAFEKLKKYLASAPILCHYRPELPCRLETDASDGVVAAVFSQLQDDGQWHPVAYYSRTMNSAEFNYDIYDKEMLAIVDALKEWRAELIG 631
                  ******************************************************************************************99998 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.1   0.0   5.7e-33   1.5e-29       2     222 .]     327     486 ..     326     486 .. 0.97

  Alignments for each domain:
  == domain 1  score: 103.1 bits;  conditional E-value: 5.7e-33
                 E-TT.S-EEE.......-THHHHCTB--.........-------HHHH.............HCCHTS--EEEEEEBCCGCCCSBB-GGGGGGG-EEET. CS
       RVT_1   2 pKkgpgsyRp.isllsvdykalnkliakrLkdvlekllsenqpgfrpgrstldavedllkalkkkkkaklllklDlkkaFdsvpleellrkltafkvpt 99 
                  K+g g+ R  +     dy++ln+l++k         + +++p +++               ++ ++a++++klD++++F++++++ +++ lt+f+++ 
  EEA19992.1 327 EKPG-GGLRFcV-----DYRKLNQLTKK---------DRYPLPLIDEV-------------FERLNRARIFTKLDIRQGFHRIRMHPESEDLTTFRCR- 396
                 5999.9****55.....***********.........***********.............8999*********************************. PP

                 ........................TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T......TEEECTTEEEEEESSHHHHHHHHHHHHHHHHHTT--B CS
       RVT_1 100 klinliksflstrsfsvrvngeeskgryekkglpqGsvlSPllfnlfmnellrelrkrakgvtllrYaDDililskskeelqelleaveewlkesglki 198
                                         +g y +k++p+G++++P++f++++n+l++++  +    +l++++DD+li+s+++ e++ +++ v e+l e+gl+ 
  EEA19992.1 397 ------------------------YGTYKYKVMPFGLTNGPATFQRLVNDLFMDCLDQ----FLIAFVDDLLIYSENEIEHEIHVKRVLERLCEAGLQA 467
                 ........................9*******************************95....9************************************ PP

                 EGGG-EEE.....ESSEEETTEEE CS
       RVT_1 199 npeKtklvlftvkseevkyLGvtl 222
                 + +K+++       ++ k+LG++l
  EEA19992.1 468 AIHKCEFH-----VTRTKFLGFIL 486
                 ********.....8*******975 PP

>> Integrase_H2C2  Integrase zinc binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.6   0.4   2.9e-17   7.5e-14       4      57 ..     798     853 ..     796     854 .. 0.96

  Alignments for each domain:
  == domain 1  score: 51.6 bits;  conditional E-value: 2.9e-17
  Integrase_H2C2   4 slrkeilkeaHds..agHlGiektlerlrrryyWpgmrkdvkkyvksCetCqrrkp 57 
                     +lr ++l+e+H +  + H+G +k++ ++r+ryyW + +kdv++yv++C  C+++++
      EEA19992.1 798 DLRARLLDEIHRQpsTVHPGKNKMKILVRERYYWETWNKDVESYVDNCMMCKHTNT 853
                     699*************************************************9997 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.8   0.0   1.3e-16   3.4e-13       3     118 ..     870     983 ..     868     984 .. 0.97

  Alignments for each domain:
  == domain 1  score: 49.8 bits;  conditional E-value: 1.3e-16
         rve   3 rpgelwqvDvtvvripdgggkayllvvvddfsrlilaealsdemdastvlalleravarfggvepervlsDngseytskafrefladlgirvsftrpgr 101
                 rp +++++D+ +++ pd+ g   ++vvvd  s+  +  ++ ++ da  +++l+ + v  + g+ p+ ++sD+g++++s+ + e+ + l i+v ++ +++
  EEA19992.1 870 RPWQHISMDFITYP-PDKAGYDTVFVVVDRLSKTPISTPCHKNVDARELARLWIKYVYPRTGL-PDSIVSDRGPQFVSEFWGEVYRILSIKVVLSTAAH 966
                 899***********.9***********************************************.*********************************** PP

         rve 102 pqdnGkvErfhrtlkde 118
                 +q+ G  E ++++l ++
  EEA19992.1 967 AQTDGQTEIANQYLSQR 983
                 *************9886 PP

>> zf-H2C2  H2C2 zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   1.8e-05     0.046       5      39 .]     815     849 ..     812     849 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.8e-05
     zf-H2C2   5 HlGinkltallarkYhwlgiketvseVissCkaCq 39 
                 H G nk++ l++++Y+w    + v+  + +C  C+
  EEA19992.1 815 HPGKNKMKILVRERYYWETWNKDVESYVDNCMMCK 849
                 99***************999999999999998886 PP

>> RVP_2  Retroviral aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   6.5e-05      0.17      90     128 ..      50      88 ..       9      94 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 6.5e-05
       RVP_2  90 giefladlilLdlkdlDviLgmdWLsknkanidcaekkv 128
                 ++++ +  ++++l + DviLg  W +k+ +  dca++++
  EEA19992.1  50 RRQLDVPFLIVNLGKHDVILGRLWFAKYGVLPDCANRQL 88 
                 4567788899999***********************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1336 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       680  (0.0379274); expected 358.6 (0.02)
Passed bias filter:                      527  (0.0293937); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.87u 0.29s 00:00:01.15 Elapsed: 00:00:00.52
# Mc/sec: 7785.15
//
Query:       EEA19993.1  [L=142]
Description: hypothetical protein PMAA_007600 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
     0.0024   18.5   0.3     0.0039   17.9   0.3    1.3  1  zf-RVT      zinc-binding in reverse transcriptase
  ------ inclusion threshold ------
      0.066   13.3   0.1      0.085   13.0   0.1    1.1  1  zf-RRPl_C4  Putative ribonucleoprotein zinc-finger pf C4 type


Domain annotation for each model (and alignments):
>> zf-RVT  zinc-binding in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.3   4.4e-07    0.0039      58      80 ..      52      74 ..      41      78 .. 0.82

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 4.4e-07
      zf-RVT 58 ssrCqlCgqeeEtieHlfleCpf 80
                +s+ ++Cgq+ Et+eH +++C++
  EEA19993.1 52 HSNLCVCGQASETVEHFLFRCTK 74
                566779***************86 PP

>> zf-RRPl_C4  Putative ribonucleoprotein zinc-finger pf C4 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.1   9.5e-06     0.085      48      94 ..      49      96 ..      28     105 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 9.5e-06
  zf-RRPl_C4 48 islrdkLCtkCkeknekeke.ircetfeeylkklklCkeCkervekvl 94
                ++ +++LC   + +++ e+  +rc++++  ++ ++ C+e k+ + ++ 
  EEA19993.1 49 RAAHSNLCVCGQASETVEHFlFRCTKWTAMREGMNQCTESKRGNLSFF 96
                566789**9889999988889*******************99988775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (142 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       363  (0.0202465); expected 358.6 (0.02)
Passed bias filter:                      271  (0.0151152); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.24s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 1002.99
//
Query:       EEA19994.1  [L=317]
Description: hypothetical protein PMAA_007610 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      4e-11   42.8   0.1      1e-10   41.4   0.1    1.8  1  Exo_endo_phos_2  Endonuclease-reverse transcriptase
    0.00099   19.6   5.7     0.0023   18.4   5.7    1.6  1  DUF16            Protein of unknown function DUF16
     0.0027   17.9   5.4     0.0046   17.2   5.4    1.3  1  Fib_alpha        Fibrinogen alpha/beta chain family
  ------ inclusion threshold ------
      0.024   14.5   2.9      0.039   13.8   2.9    1.3  1  Dynactin_p22     Dynactin subunit p22
      0.048   13.3   2.7       0.56    9.8   2.8    2.0  2  Phage_GPO        Phage capsid scaffolding protein (GPO) serin
       0.18   12.4   3.6        0.6   10.8   3.6    2.0  1  SlyX             SlyX
       0.33   11.3   3.8       0.72   10.2   3.8    1.6  1  BLOC1_2          Biogenesis of lysosome-related organelles co
        0.5    9.7   3.3       0.77    9.1   3.3    1.2  1  FAM76            FAM76 protein
        3.7    8.1   6.6        6.5    7.3   1.9    2.9  3  GlutR_dimer      Glutamyl-tRNAGlu reductase, dimerisation dom


Domain annotation for each model (and alignments):
>> Exo_endo_phos_2  Endonuclease-reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.4   0.1   5.3e-14     1e-10      54     118 ..     163     228 ..     124     229 .. 0.89

  Alignments for each domain:
  == domain 1  score: 41.4 bits;  conditional E-value: 5.3e-14
  Exo_endo_phos_2  54 sargeeLiefleehslsllnllksg.ptfkssngsstiDltltsdnlals..kleleeedlgSDHrpi 118
                      + ++e L+++++ehsl+  +ll++g +t++s + ++tiDl+l+s++la++  k  ++ +++gSDH++i
       EEA19994.1 163 QGEAEVLVDYMTEHSLQ--SLLPRGtKTWHSGDLETTIDLVLASTELAEEmvKYGIHYTNHGSDHQAI 228
                      68999************..999999688888777****************99999999*******998 PP

>> DUF16  Protein of unknown function DUF16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   5.7   1.1e-06    0.0023      29      89 ..      65     125 ..      36     143 .. 0.80

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 1.1e-06
                 -..BHHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHHHHHHHHH.......HHHHHH CS
       DUF16  29 kdsnkqrLkkieakvdklgeqinkleqkvekqgekikelkveqkaqgeelnkvdetlelil 89 
                 kd n   Lkki + +++  ++++ l++++ +qg+ ike+++ + aq+  +++++  +e i 
  EEA19994.1  65 KDGNRDMLKKIGQYLESTYQEVKGLKEIIIEQGKMIKEQSEMIRAQSSTIQALQTQVEAIE 125
                 5569999999999999999999999999999999999999999999999997777777663 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   5.4   2.3e-06    0.0046      48     138 ..      40     134 ..      28     138 .. 0.79

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 2.3e-06
                 CCHHHHHH.HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH...HCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSB-EE CS
   Fib_alpha  48 snstkeae.elvkeikdslrekqkskkdndnvikksskele...eeilrlketidaqesnirvLqnvlesneqkiqkLeqdidqkerkCkepCkd 138
                 ++s +++e + vk+    ++ekq+ k++n  ++kk+ + le   +e+  lke i++q + i++  ++++++++ iq L++++++ e++  e Ck+
  EEA19994.1  40 KKSMTQVElTAVKKAAGLIEEKQSGKDGNRDMLKKIGQYLEstyQEVKGLKEIIIEQGKMIKEQSEMIRAQSSTIQALQTQVEAIESQSIEECKQ 134
                 4444444414577788889999999999988888888888822245667899********************************99999999997 PP

>> Dynactin_p22  Dynactin subunit p22
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   2.9   1.9e-05     0.039      35     129 ..      52     145 ..      30     153 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.9e-05
  Dynactin_p22  35 akvqkklssavskrekikellkkleelekyLdpeyedseelpde..vKleliLaeedeLkktaalleqlqeLkpvldseeikdvpelkekLekLsqi 129
                   +k+   +++  s+++  +++l   +++ +yL+++y++ + l++      ++i ++ + ++ + + ++ lq   + ++s++i++ ++l e+L++++  
    EEA19994.1  52 KKAAGLIEEKQSGKDGNRDML---KKIGQYLESTYQEVKGLKEIiiEQGKMIKEQSEMIRAQSSTIQALQTQVEAIESQSIEECKQLWEQLNTIASA 145
                   555555555555555555554...55789*********998887433567888888899999*******************************9875 PP

>> Phage_GPO  Phage capsid scaffolding protein (GPO) serine peptidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   2.8   0.00028      0.56     161     266 ..      44     157 ..      27     162 .. 0.78
   2 ?    0.9   0.0      0.14   2.8e+02     148     173 ..     273     298 ..     263     312 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00028
   Phage_GPO 161 talefeeeeeeee....geslferikallskkkksddarfadveeavelvAeevkelsekveallaleaelaalkkeveklka....eleaLkekLskt 251
                 t++e+++ ++ +     ++s  +  + +l+k  +  + + ++v+   e + e+ k ++e+ e   a+++ ++al+++ve  ++    e+++L e+L++ 
  EEA19994.1  44 TQVELTAVKKAAGlieeKQSGKDGNRDMLKKIGQYLESTYQEVKGLKEIIIEQGKMIKEQSEMIRAQSSTIQALQTQVEAIESqsieECKQLWEQLNTI 142
                 4555555555544444345555667889999999999999999999999999999999999988899999999999998877656668999******99 PP

   Phage_GPO 252 dakekqrpeatGeeg 266
                  +   +   atG+++
  EEA19994.1 143 ASAPAKATYATGGNQ 157
                 999999999999765 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.14
   Phage_GPO 148 kqspenlftaavetalefeeeeeeee 173
                 +q+ + l+t+ +e++l+++ +++ + 
  EEA19994.1 273 QQQTDHLMTVVIEAVLKLTPKAKPSP 298
                 7899**************98887665 PP

>> SlyX  SlyX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   3.6    0.0003       0.6      12      47 ..      93     128 ..      82     150 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.0003
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT- CS
        SlyX  12 lafqedtieeLndvvaeqqqqidrlqrqlrllaerl 47 
                 +  q ++i+e ++++ +q  +i++lq+q+++++ + 
  EEA19994.1  93 IIEQGKMIKEQSEMIRAQSSTIQALQTQVEAIESQS 128
                 667889999999999999999999999999988775 PP

>> BLOC1_2  Biogenesis of lysosome-related organelles complex-1 subunit 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   3.8   0.00036      0.72       3      79 ..      50     126 ..      49     144 .. 0.93

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00036
     BLOC1_2   3 mfekvskyleaeleatvedyklLeklNeaasekykklkdvaaslekkleklnekyeelqpylqqidqiekqvteLee 79 
                 +++k++ ++e++ ++   + ++L+k+ +  ++ y+++k   + + ++ + ++e++e ++ + + i+++++qv+ +e+
  EEA19994.1  50 AVKKAAGLIEEKQSGKDGNRDMLKKIGQYLESTYQEVKGLKEIIIEQGKMIKEQSEMIRAQSSTIQALQTQVEAIES 126
                 578889999999999999999****************************************************9996 PP

>> FAM76  FAM76 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   3.3   0.00039      0.77     178     272 ..      38     137 ..       9     148 .. 0.74

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00039
       FAM76 178 khkkrssrlevskleeek.....laeekesnetskksldsnssdhlvavtqLkeeiaslkkqleqkdqellekdkkitelkaellekekelreklkele 271
                  +kk+ +++e +++++       +++ k +n+++ k++ +       +v+ Lke i +  k+++++ +++ ++  +i +l+++ +  e++  e  k+l 
  EEA19994.1  38 TSKKSMTQVELTAVKKAAglieeKQSGKDGNRDMLKKIGQYLESTYQEVKGLKEIIIEQGKMIKEQSEMIRAQSSTIQALQTQVEAIESQSIEECKQLW 136
                 22333334445555422233333556677777777789999999999***************************************9999888777765 PP

       FAM76 272 k 272
                 +
  EEA19994.1 137 E 137
                 5 PP

>> GlutR_dimer  Glutamyl-tRNAGlu reductase, dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.2      0.21   4.2e+02      23      55 ..      30      63 ..      21      91 .. 0.73
   2 ?    7.3   1.9    0.0033       6.5      12      49 ..      99     137 ..      89     150 .. 0.72
   3 ?   -1.2   0.0       1.4   2.8e+03      46      75 ..     156     187 ..     135     205 .. 0.68

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.21
                 HHHHHHHHHHHHHHHHHHHHHHHS-S...----- CS
  GlutR_dimer 23 vptIkalrekaeeireeeleralkkla.ldgedr 55
                 +++I+a+r++ +++ + el+ ++k  + +++++ 
   EEA19994.1 30 SDIISAVRTSKKSMTQVELTAVKKAAGlIEEKQS 63
                 6789999999999999999999998887666664 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0033
                  HHHHHHHHH.HHHHHHHHHHHHHHHHHHHHHHHHHS-S. CS
  GlutR_dimer  12 efeawlksl.evvptIkalrekaeeireeeleralkkla 49 
                   ++++ +   + + tI+al++++e+i  + +e++++  +
   EEA19994.1  99 MIKEQSEMIrAQSSTIQALQTQVEAIESQSIEECKQLWE 137
                  44444444404579******************9998766 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 1.4
                  S-S...-------.-TTHHHHHHHHHHHHHHH CS
  GlutR_dimer  46 kkla.ldgedree.lekltrslvnkllhepta 75 
                  ++++  ++ ++e+ ++ +t++  + ll   t+
   EEA19994.1 156 NQISpARQGEAEVlVDYMTEHSLQSLLPRGTK 187
                  55555666778888899998888888866555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (317 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1451  (0.0809303); expected 358.6 (0.02)
Passed bias filter:                      719  (0.0401026); expected 358.6 (0.02)
Passed Vit filter:                        89  (0.00496402); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.59u 0.31s 00:00:00.89 Elapsed: 00:00:00.50
# Mc/sec: 1921.18
//
Query:       EEA19995.1  [L=356]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.7e-09   36.0   0.0    1.1e-08   35.3   0.0    1.3  1  APH             Phosphotransferase enzyme family
    0.00094   18.8   0.0     0.0014   18.3   0.0    1.2  1  Choline_kinase  Choline/ethanolamine kinase
  ------ inclusion threshold ------
      0.023   14.1   0.0      0.045   13.1   0.0    1.4  1  Kdo             Lipopolysaccharide kinase (Kdo/WaaP) family
       0.13   11.8   0.1       0.19   11.3   0.1    1.1  1  MASE3           Membrane-associated sensor domain


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.3   0.0   2.5e-12   1.1e-08     163     209 ..     262     315 ..     237     350 .. 0.82

  Alignments for each domain:
  == domain 1  score: 35.3 bits;  conditional E-value: 2.5e-12
                 SS-EEEE-SS-SGGGEEEC.........TTEEEEE---TT-EEEECCHHHHCCH CS
         APH 163 elptvllHgDlhpgNllvd.......pddgrvtGviDfedaglgpplyDlavll 209
                   + v++H Dl+p+N+lvd       +++++vtG++D+e++g+ p  +D   + 
  EEA19995.1 262 GHKIVFTHADLNPRNILVDrmvqpdgSRGWKVTGIVDWETSGYYPEYWDYTKAM 315
                 35789*********************9******************999987665 PP

>> Choline_kinase  Choline/ethanolamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   3.1e-07    0.0014     140     186 ..     260     314 ..     238     328 .. 0.80

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 3.1e-07
                     CHGG-EEEE-S--SGGGEEE.........-CTTEEEE--GTT-EEEEHHHHHHHH CS
  Choline_kinase 140 elespvvfcHnDlqegNill........nkeekklvlIDFEYagynyrgfDlanh 186
                     +  +++vf H Dl ++Nil+        +   k   ++D+E +gy +  +D    
      EEA19995.1 260 RRGHKIVFTHADLNPRNILVdrmvqpdgSRGWKVTGIVDWETSGYYPEYWDYTKA 314
                     45678***************99*999854444555699*********99997665 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0     1e-05     0.045     121     154 ..     249     282 ..     236     300 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1e-05
         Kdo 121 rallkavgrliaklhragvnHadlyaknillqqe 154
                 +++l+  g ++++ h++   Hadl+++nil++  
  EEA19995.1 249 NQTLRYSGDAARRGHKIVFTHADLNPRNILVDRM 282
                 56677779999999*****************865 PP

>> MASE3  Membrane-associated sensor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   4.3e-05      0.19     154     212 ..      88     146 ..      75     150 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 4.3e-05
       MASE3 154 llalllllrrrkkfekkvlrlllaalvllilsellftlyvsvydilnllGHlfkilsfy 212
                 l+  + ++   kkf    l +++ +l++  ls +++ + +   +il ++GHl ++++++
  EEA19995.1  88 LCKSIRYFELTKKFAADRLPCVSGSLICRSLSYFFVQFQQAHRGILSITGHLTRVFGVI 146
                 667788889999*******************************************9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (356 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       266  (0.0148363); expected 358.6 (0.02)
Passed bias filter:                      252  (0.0140554); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.66u 0.31s 00:00:00.97 Elapsed: 00:00:00.56
# Mc/sec: 1930.33
//
Query:       EEA19996.1  [L=509]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (509 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       711  (0.0396564); expected 358.6 (0.02)
Passed bias filter:                      559  (0.0311785); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.71u 0.29s 00:00:01.00 Elapsed: 00:00:00.53
# Mc/sec: 2900.67
//
Query:       EEA19997.1  [L=233]
Description: hypothetical protein PMAA_007640 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (233 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       597  (0.033298); expected 358.6 (0.02)
Passed bias filter:                      403  (0.0224776); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.48
# Mc/sec: 1466.85
//
Query:       EEA19998.1  [L=216]
Description: hypothetical protein PMAA_007650 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
       0.71   10.3   6.9        3.9    7.9   0.2    2.4  2  E2F_CC-MB  E2F transcription factor CC-MB domain


Domain annotation for each model (and alignments):
>> E2F_CC-MB  E2F transcription factor CC-MB domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   1.8    0.0021        37      10      55 ..      15      60 ..       7      65 .. 0.82
   2 ?    7.9   0.2   0.00022       3.9       6      54 ..     101     156 ..      98     169 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0021
   E2F_CC-MB 10 eeeqkLDelieklteqlknltedeknqlaYvtyedirsiasfkeqt 55
                +++ +L e++e ++e+ ++  e++++++++ ++ d+ + a+   q+
  EEA19998.1 15 QMQYRLIEQMEAMQEKQERRDEEKERRYLFREQRDLLTQAQAPHQM 60
                5667888999999999999988888889********9988777666 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.00022
   E2F_CC-MB   6 esleeeeqkLDelieklteqlknl.tedeknq......laYvtyedirsiasfkeq 54 
                 +s+e+ e++ D+l++++  +++++ +ed k++        + ++  ir++++++++
  EEA19998.1 101 SSMESGEDEYDTLMKFFAWKINSIkNEDRKEKwkraqtIIFTNDWSIRELRQMEDD 156
                 689999******************88888887888888888888888888887775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (216 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1408  (0.078532); expected 358.6 (0.02)
Passed bias filter:                      503  (0.0280551); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 1466.45
//
Query:       EEA19999.1  [L=636]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      4e-37  128.0   0.2    6.9e-37  127.2   0.2    1.4  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    2.8e-35  121.5   0.0    4.1e-35  121.0   0.0    1.2  1  adh_short        short chain dehydrogenase
    1.7e-10   40.8   0.0    3.4e-10   39.8   0.0    1.5  1  DDE_3            DDE superfamily endonuclease
    5.1e-07   29.8   1.4      2e-06   27.8   0.1    2.1  2  KR               KR domain
  ------ inclusion threshold ------
      0.012   15.6   0.0      0.023   14.7   0.0    1.4  1  ADH_zinc_N       Zinc-binding dehydrogenase
      0.014   14.8   0.0      0.028   13.8   0.0    1.4  1  DUF1776          Fungal family of unknown function (DUF1776)
      0.027   15.1   0.4      0.095   13.3   0.1    2.1  2  HTH_32           Homeodomain-like domain
      0.035   14.0   0.1       0.07   13.0   0.1    1.5  1  3HCDH_N          3-hydroxyacyl-CoA dehydrogenase, NAD binding
       0.21   10.7   0.0        0.3   10.2   0.0    1.2  1  Polysacc_synt_2  Polysaccharide biosynthesis protein


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.2   0.2   3.5e-40   6.9e-37       1     232 [.      22     279 ..      22     280 .. 0.87

  Alignments for each domain:
  == domain 1  score: 127.2 bits;  conditional E-value: 3.5e-40
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGH....HHHHHHHHHHTT.SEE....EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EG...... CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneea....kkrveelaeelg.aev....lecDVtdeeqvealveevvekfgklDilvnnagiapk...... 82 
                   GaasgIG+ iA+ +  +Ga+ +l d+ne+a    k++++ la+ lg +++     + D ++ee v+++v++++ ++++lD+l+++agi         
    EEA19999.1  22 GAASGIGHMIARGCTINGANTILIDVNEDAlekvKAELQGLASTLGwNSLkielGHGDLSSEEGVKKVVDTIKTSHESLDCLIHCAGIRFMndityt 118
                   9***************************99522234455566666652224477899******************************9766668888 PP

                   .......CSS-GGGH-HHHHHHHHHHHTHHHHHHHHHHHH....HCTSC....CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTE CS
  adh_short_C2  83 .......lkgpfletsreefdraldvnlyslfllakaalp....lmkeg....gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgi 164
                          l++ +l+++ +++++++ vn+ + ++l+  ++     +++ +    gs++  ss ++    +   +y+++Kaa+ +l+r +A+e+++  i
    EEA19999.1 119 pgdglskLEAATLSAPYQGWEKVFRVNVLAPYYLTAGLVTllgaAAA-QgdgkGSVIMFSSPASVHNHQFVPIYQTSKAAVDHLVRIMAAEFADFYI 214
                   88999999999999********************9999995443233.25889***********99999999************************* PP

                   EEEEEEE--BHCTGGGGSTTHHHHHHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEESTT CS
  adh_short_C2 165 RvNavspgpikTlaasgikgfdelleelearaplgrlgtpeevaeaalfLasdeasyitGqtlvvDgG 232
                   RvNa+spg++   ++    +      +l+a+ap gr+g+ e++  +al+L+s++ s++  +++ + gG
    EEA19999.1 215 RVNAISPGIVPSGMTP---DDGTSNLRLAAKAPAGRAGNEEDMVGTALWLMSKAGSFMDEKVIRAEGG 279
                   ***********88865...44566678899****************************9999999888 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.0   0.0     2e-38   4.1e-35       2     188 ..      17     230 ..      16     236 .. 0.91

  Alignments for each domain:
  == domain 1  score: 121.0 bits;  conditional E-value: 2e-38
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT.......TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---S...... CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee.......gakalaiqvDvtdreevealvekavkklgkldvLvnNAGi...... 87 
                 +v +tGa+sGIG+ ia+ +  +Ga+++++d +e++le+v++el+ +       + k+   ++D++++e v+++v++++  +++ld+L+++AGi      
  EEA19999.1  17 WVAITGAASGIGHMIARGCTINGANTILIDVNEDALEKVKAELQGLastlgwnSLKIELGHGDLSSEEGVKKVVDTIKTSHESLDCLIHCAGIrfmndi 115
                 799*****************************************9876666656679999*************************************** PP

                 .........S--SSGGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHH.....HCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTE CS
   adh_short  88 .........tgsgpfselseeewervievNltgvflltravlpaml.....kqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgi 172
                          +  +++ +   + we+v+ vN+ +++ lt+ +++ +         +G+++  sS a+      v+ Y +sKaav++l+r +a e+a+  i
  EEA19999.1 116 tytpgdglsKLEAATLSAPYQGWEKVFRVNVLAPYYLTAGLVTLLGaaaaqGDGKGSVIMFSSPASVHNHQFVPIYQTSKAAVDHLVRIMAAEFADFYI 214
                 ****999743334444444555******************999987888878899******************************************** PP

                 EEEEEEESSBSSHHHH CS
   adh_short 173 rvnavaPGlvdTdmak 188
                 rvna+ PG+v ++m+ 
  EEA19999.1 215 RVNAISPGIVPSGMTP 230
                 ***********99986 PP

>> DDE_3  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.8   0.0   1.7e-13   3.4e-10       2      74 ..     559     634 ..     558     636 .] 0.95

  Alignments for each domain:
  == domain 1  score: 39.8 bits;  conditional E-value: 1.7e-13
       DDE_3   2 vvfiDEsgfqlgt.vrrrawakkGkrer.leeygrrgrvnligaldekgglaf.vtfeetlnaedfaeflerllet 74 
                 +vf+DEs f+++t +r++a+a++G +++ +++ +r++++++++a++ +g l +  + ++++na df ++le+ +++
  EEA19999.1 559 LVFLDESIFNEKTgWRQHAYAPIGDDAEiDANINRGKTWSICAAMTLEGYLPCtGIKDGYYNAGDFTDWLETKIDS 634
                 89************************887************************99****************98875 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.1     1e-09     2e-06       4      92 ..      19     110 ..      17     129 .. 0.86
   2 ?    0.3   0.1      0.28   5.5e+02     131     164 ..     173     206 ..     156     213 .. 0.88

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 1e-09
                 EEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHT.T-...EEEE----TT-HHHHHHHHHHHHHHSS---EEEE----- CS
          KR   4 litGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaeleal.ga...evevvaaDvsdkdavealleeikaeeppikGvihaAgvl 92 
                  itG++ g+G  +ar    +ga+++++   +  a e+ ka+++ l+++ g    ++e+ + D+s+++ v++++++ik++++++   ih+Ag+ 
  EEA19999.1  19 AITGAASGIGHMIARGCTINGANTILIDVNE-DALEKVKAELQGLASTlGWnslKIELGHGDLSSEEGVKKVVDTIKTSHESLDCLIHCAGIR 110
                 69***********************999888.66777777777777754434449************************************85 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.28
                 EEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHH CS
          KR 131 fvlfSSiagllgsagqanYaaaNaflDalaeyrr 164
                 +++fSS a++  ++    Y++  a +D l++  +
  EEA19999.1 173 VIMFSSPASVHNHQFVPIYQTSKAAVDHLVRIMA 206
                 79************9999***9999999998765 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   0.0   1.2e-05     0.023       1      66 [.      26      93 ..      26     115 .. 0.66

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.2e-05
                HHHHHHHHHHHHTT-EEEEEESSHHHHHHHHH.T.TESEEEETTTC.HHHHHHHHHTTTSSEEEEEESS CS
  ADH_zinc_N  1 gvGlaavqlAkalGaeviavdsseeklelakk.l.Gadevinykea.dlverikeltggegvdvvfecv 66
                g+G++    + + Ga++i +d++e+ le++k  l G   ++ + +  +++    +l  +egv+ v++++
  EEA19999.1 26 GIGHMIARGCTINGANTILIDVNEDALEKVKAeLqGLASTLGW-NSlKIELGHGDLSSEEGVKKVVDTI 93
                8*****************************9875467777777.2224444444444444444444443 PP

>> DUF1776  Fungal family of unknown function (DUF1776)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   1.4e-05     0.028     112     199 ..     134     223 ..     129     243 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.4e-05
     DUF1776 112 plsswaselnerllspiltlqallplltsra...kqkakiivvnpsissslnlpfhapEalvssalsalfevLkrelrphnidvtqikLGn 199
                 p + w++++  ++l+p+ ++ +l++ll ++a     k  +i+++ s  s  n +f ++  +   a+++l++++++e ++  i v  i  G+
  EEA19999.1 134 PYQGWEKVFRVNVLAPYYLTAGLVTLLGAAAaqgDGKGSVIMFS-SPASVHNHQFVPIYQTSKAAVDHLVRIMAAEFADFYIRVNAISPGI 223
                 5689************************9888877788888887.55667799**************************999999998776 PP

>> HTH_32  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.1   4.8e-05     0.095      21      72 ..     469     521 ..     458     522 .. 0.80
   2 ?    0.4   0.1      0.53   1.1e+03      37      54 ..     518     534 ..     518     542 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 4.8e-05
      HTH_32  21 prr.grprklsdevrariiallreeprW.sprqlaarlaeregvkvShstvyri 72 
                  r  gr rklsd+ +++i + l +e  W   ++++ +l  ++ v+vS st+ r+
  EEA19999.1 469 YRTlGRARKLSDADEDAIFEYLLHE-PWrQQDEVRFWLYYERDVDVSTSTICRL 521
                 56679*****************555.6835566888**7777899******875 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.53
      HTH_32  37 iiallreeprWsprqlaa 54 
                 i++l  +++rWs +ql +
  EEA19999.1 518 ICRLF-KRRRWSRKQLKR 534
                 67788.556*****9986 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.1   3.5e-05      0.07       2      70 ..      18      96 ..      17     107 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 3.5e-05
                EEEE--.SCCHHHHHHHHHHTT-EEEEE-S-HHHHHHHHHHHHH........HHHCCTTTTSS-..........HHHHCCCHHCEEEE CS
     3HCDH_N  2 vaviGa.GtmGagiaavfasagleVvlvdiseealekalekiek........sleklvekgklk..........eeeveaalarisft 70
                va+ Ga   +G+ ia  +  +g ++ l+d++e+alek++++++         sl         k          ee v++++++i+++
  EEA19999.1 18 VAITGAaSGIGHMIARGCTINGANTILIDVNEDALEKVKAELQGlastlgwnSL---------KielghgdlssEEGVKKVVDTIKTS 96
                7888874459******************************99973333322222.........2223333344566666666666665 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   0.00015       0.3       1      85 [.      18     107 ..      18     124 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00015
                      EEEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH.........-TTEEEE....E--TT-HHHHHHHTT..T.....-SEEEE-- CS
  Polysacc_synt_2   1 vlvtGagGsiGselvrqilkkkpkkiillerdElklyeieke...leeelkkkklkveivpvigdvrdkerlekaleelk.....vdvvfhaA 85 
                      v +tGa+  iG+ + r ++ + ++  il++ +E +l +++ e   l ++l  ++lk+e     gd+  +e ++k+++++k      d+++h+A
       EEA19999.1  18 VAITGAASGIGHMIARGCTINGAN-TILIDVNEDALEKVKAElqgLASTLGWNSLKIE--LGHGDLSSEEGVKKVVDTIKtshesLDCLIHCA 107
                      67**********999888776665.5678*************4333334444445444..556899999988888876541111145666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (636 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       453  (0.0252663); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.62u 0.28s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 4290.42
//
Query:       EEA20000.1  [L=522]
Description: cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.8e-35  122.6   0.1    2.6e-20   72.6   0.1    2.1  2  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.5   0.0     3e-17   5.4e-13       4     278 ..      51     314 ..      48     320 .. 0.77
   2 !   72.6   0.1   1.5e-24   2.6e-20     323     436 ..     345     457 ..     314     466 .. 0.87

  Alignments for each domain:
  == domain 1  score: 48.5 bits;  conditional E-value: 3e-17
                 ESEHHCCHCHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTT..CGH..HHHHHH CS
        p450   4 ptplplvgnllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlf..ang..ekwkkl 98 
                 p+   l g+l qlg  ++  +  ++ +    pif+l++g++ +++l++ ea++e  ik++   s++ d+++++t+++    ++ ++  +++  e++kk+
  EEA20000.1  51 PNGDLLAGHLYQLGD-DHATRSETWTNTYGWPIFQLRMGRRWAIMLNSFEAAREWIIKNQ---SATLDRPWFHTFHGVISATSAATigTSPwdERTKKQ 145
                 555678899999995.555554455555556****************************7...555677888887765555444431122345666666 PP

                 HHHHHHHHTSH.STTTHHHHHHHHHHHHHHHHHCCCCHCSEEETHHHH..HHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCC CS
        p450  99 Rrfltptltsf.gklsleelveeeaedlveklrkkagesselditell..skaaldvigsilFgarfdlledeklselvkaveelssllskssvqllll 194
                 Rr++  ++t++  +++l+++++ e+  ++ ++  ++++ s  di +++   + al+ +++ ++g rf++ +d++l++++    ++ s+ s++s+   ++
  EEA20000.1 146 RRVV-GSFTTGpSIQKLRNMLDMETCAMISAIYYDSQKGS-NDIMPHIypKRLALNLMTMFCYGTRFSTTTDPMLLQILSDASTIASFRSTNSTTQ-DF 241
                 6655.5566665888*****************99999985.66666663379*********************************99887777555.55 PP

                 CHHHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHH CS
        p450 195 fpllkylptkllrklkeavkklkdlldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTt 278
                 +p l+y+  + + +      ++++   +l+++ r+t+    + +r+ ++a+ll++    +++ l++ ++++ ++ l+ +G++T 
  EEA20000.1 242 IPHLRYVSRNGRND------TAIQARARLLNKVRDTVTLF-SGPRKSVAAMLLTD----NQEGLTQLDIKTILGGLMSGGFETL 314
                 55588887544444......55788889999999999998.68999999999995....3347********************6 PP

  == domain 2  score: 72.6 bits;  conditional E-value: 1.5e-24
                 HHHHHHHHHHHHSCSSTTEEEEESSSCEEETTEEE-TT-EEEEEHHHHHT-TTTS.SSTTS--GGGGB-TTSCTESSCTT--TTEEGGGS-TTHHHHHH CS
        p450 323 yldavikEtLRlhpvvplllpRevtkdvvirgylipkGtevivnlyalhrdpevf.pnPeeFdpeRFldekgnskrksfaflPFGaGpRnCiGerlArm 420
                 y    +kE+LR++p++ ll   ++ k+   +g  ipkG  v +n++a++rdp+ + p++++F+peR+ +++   k+++ +++ FGaG+R+C   ++   
  EEA20000.1 345 YICGLVKEALRFYPPLKLLPAWQTYKEFNYQGAEIPKGVLVYINAQAINRDPATYgPDADQFRPERWVENTY--KVPPPYHFSFGAGARMCTAVNFSNR 441
                 667789***********99999************************************************88..6****************99999999 PP

                 HHHHHHHHHHHHEEEE CS
        p450 421 elklflatlLqnFeve 436
                  l  ++ +l+  F+++
  EEA20000.1 442 VLYAMFLRLIVSFKIT 457
                 9999999998888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (522 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       515  (0.0287244); expected 358.6 (0.02)
Passed bias filter:                      460  (0.0256568); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.26s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3573.18
//
Query:       EEA20001.1  [L=430]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-29  103.9   0.5    6.5e-29  101.3   0.5    1.9  1  Amidohydro_1  Amidohydrolase family
    4.8e-11   42.8   2.6    3.5e-06   26.8   0.3    2.6  2  Amidohydro_3  Amidohydrolase family


Domain annotation for each model (and alignments):
>> Amidohydro_1  Amidohydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.3   0.5   7.2e-33   6.5e-29       1     334 [.      62     419 ..      62     422 .. 0.88

  Alignments for each domain:
  == domain 1  score: 101.3 bits;  conditional E-value: 7.2e-33
                   EEEE-EEEEEEECETTECSSS..GHHHHH.STTHHHHHHHHHHHHHHHHTTEEEEEEEEHSSTH.HHHHHHHHHHT.SSSEEEEEEESSEGGS.... CS
  Amidohydro_1   1 ivlPGlIDaHvHleqsllrga..tledwl.vppetaaealesgiktalksGtttvadmgattst.giealleaaee.lplglrilggkvsldr.... 88 
                   +v+PGl+DaH+H++   + ++   l++ + ++  +  +   ++++tal +G tt +d g    + +++ l++a+ + l lg+r++++  +l+     
    EEA20001.1  62 YVMPGLVDAHTHIFLH-SYDEvgALQQKRdESMTERVVRGVNHCRTALLAGYTTYRDLGSEGMQeSDANLRDAIARgLTLGPRLFVATKVLAStgsf 157
                   69***********833.333357677777999999*************************999999999999988899*********999999**** PP

                   .....................GCCCSHHHHHHHHHHHHHHHHHHCTTTCEEEEEEECGTCCSHHH.....................HHHHHHHHHHH CS
  Amidohydro_1  89 .....................gsaetskasreklkagaaetikgkadgvvkvalapheapafsde.....................elkealkeakk 143
                                        g+++++ a+r++++ag a++ik++ad +    ++ +++ +  +                      e+ ++++ea+ 
    EEA20001.1 158 ecrtensagghcvptscdavdGVEQCRQAVRRRIAAG-ADIIKFFADYRRR--IMRAPPKQQHPYipgvlhppkdpnpdymvfsqeEMNMIVSEAAL 251
                   *************************************.8**********66..666656666666689***************************** PP

                   HTTEEEEEETSSCHHHHHHHHHHTTTEEEETTTTSTCCHHTTTHCCEEEHCTCEEEHHHHHHHHHHHHHHCEEHHHHHHHHSEHHHHHHHHHHHHTS CS
  Amidohydro_1 144 rdlpvaiHaletkgevedaeaafgetiehgthlevaeslglldeiklilahgvhltpteaellkerlkeagvahcpfsnsilrsgrealrkaldeGv 240
                   +++pv++H++ ++g+  +a++a+++tieh++++ +       +  k +l+++v l pt a+   e+l             + ++ ++++++a++ Gv
    EEA20001.1 252 AGAPVSAHCCTLEGAL-AAIEAGANTIEHAYFTTD-------EMFKHMLEKNVILVPTLAIA--EKLH----------TKRFDQILRNVKRAHEFGV 328
                   ***************9.999***************.......56699***********3333..3311..........33578999999***999** PP

                   CEEEEEECT..TSSCCGGHHHHHHHHHHHHHHCCTTTTHCHCHHHHHHHHHTHHHHHHTT-T...TTSSSS-TTSB--EEEECCCT......CGGGT CS
  Amidohydro_1 241 kvglgtDga..asgnslnlleelrlalklqrgllyedeegglslkealrmaTingAkalgld...dkvGsievGkdADlvvvdldi......laafv 326
                   + + g D    ++g+++   +el l++           e+g++++++l+ +T +g + +g d   ++ G +e+G +AD++++d d+      l +++
    EEA20001.1 329 HLACGGDTGtySHGDNA---RELELMI-----------EAGIPVADVLESCTVGGWEDCGGDlcgRRFGWFEEGTQADIIALDEDPaqladaLRKIN 411
                   *******7778999999...*******...........99**************9975553222249*****************6667778899999 PP

                   TTCTSEEE CS
  Amidohydro_1 327 glkkdgnv 334
                   ++ kd +v
    EEA20001.1 412 FVMKDAKV 419
                   99988766 PP

>> Amidohydro_3  Amidohydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.3   3.9e-10   3.5e-06       3      26 ..      56      79 ..      55     107 .. 0.80
   2 !   15.8   0.1   8.3e-07    0.0074     249     455 ..     215     406 ..      79     422 .. 0.73

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 3.9e-10
  Amidohydro_3  3 iDakGrlvlPGFvDsHtHlagggv 26
                  +D++G++v+PG+vD+HtH++ + +
    EEA20001.1 56 VDLRGKYVMPGLVDAHTHIFLHSY 79
                  8*****************987764 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 8.3e-07
  Amidohydro_3 249 ltepyf...........tgwpdfedealaelvaaadergldvaihaigdaavddvldafeaaaekngnqdrrrlehaegvtesqiervaalqvaagv 334
                    ++py              ++ f++e+++++v++a+ +g +v  h+ + + +    +     a + g +   ++eha ++t++  + + + +v+   
    EEA20001.1 215 QQHPYIpgvlhppkdpnPDYMVFSQEEMNMIVSEAALAGAPVSAHCCTLEGAL---A-----AIEAGAN---TIEHAYFTTDEMFKHMLEKNVILVP 300
                   45566678888888888888899999999999999999999999998766655...2.....3344455...8999999999999999999998887 PP

  Amidohydro_3 335 qpvfnfedelldsrlgperargs.tpvkellnagvkvalgsDapvgpfdpwprigaavmrktrrggevlrpdeelsleealalyTrgpAkalg..le 428
                    ++        +++l ++r++++  +vk+  + gv++a g D     +  +++   a  +        l ++  +++ ++l  +T g+++ +g  l+
    EEA20001.1 301 TLAI-------AEKLHTKRFDQIlRNVKRAHEFGVHLACGGD-----TGTYSHGDNAREL-------ELMIEAGIPVADVLESCTVGGWEDCGgdLC 378
                   7333.......467889999999999****************.....2222222222222.......356999*****************9995567 PP

  Amidohydro_3 429 drk.GtLevGadADlvvldadpldvdpp 455
                    r+ G+ e+G +AD++ ld dp+++ ++
    EEA20001.1 379 GRRfGWFEEGTQADIIALDEDPAQLADA 406
                   7999********************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (430 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       408  (0.0227564); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 2952.26
//
Query:       EEA20002.1  [L=105]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-15   57.4   8.4    1.2e-15   57.3   8.4    1.0  1  MFS_1         Major Facilitator Superfamily
    7.8e-06   25.0   5.8    9.4e-06   24.7   5.8    1.1  1  Sugar_tr      Sugar (and other) transporter
     0.0056   15.6   3.3     0.0062   15.4   3.3    1.0  1  MFS_1_like    MFS_1 like family
  ------ inclusion threshold ------
      0.054   12.0   3.7      0.061   11.9   3.7    1.1  1  MFS_2         MFS/sugar transport protein
        0.1   12.1   2.2       0.12   11.9   2.2    1.2  1  L6_membrane   L6 membrane protein
       0.18   11.9   0.1       0.22   11.6   0.1    1.1  1  Spore_III_AF  Stage III sporulation protein AF (Spore_III_AF)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.3   8.4   4.2e-19   1.2e-15      46     147 ..       2     103 ..       1     105 [] 0.93

  Alignments for each domain:
  == domain 1  score: 57.3 bits;  conditional E-value: 4.2e-19
       MFS_1  46 avaslplGrlsdrfGrrrvlllglllfalg.lllllfasslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllgg 142
                 a+ ++++   sd fG r  l++++++f+lg +l++   ++ + +l+   ++ G+g+g+lf ++ +++ad++p +e  +++++++++++lG+ +gp++gg
  EEA20002.1   2 AAVQPLYRQASDIFGKRVPLIISIAMFILGsGLCGG--ANNTaMLIHIKAFGGVGGGGLFVMVDIIVADLVPLRESQKYMSMVMGTSALGTFVGPIIGG 98 
                 6778999999********************888888..56666******************************************************** PP

       MFS_1 143 llass 147
                 ++as 
  EEA20002.1  99 AIASK 103
                 **975 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   5.8   3.1e-09   9.4e-06      69     161 ..      11     100 ..       7     105 .] 0.94

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 3.1e-09
                 HHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Sugar_tr  69 lgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglgl 161
                 ++d+fG++  l+i++++f+ g+ l++ a+   ++ +li  + + G+g G+  v+v + ++ + p +   + +s+     ++G +v+ i+g ++
  EEA20002.1  11 ASDIFGKRVPLIISIAMFILGSGLCGGAN---NTAMLIHIKAFGGVGGGGLFVMVDIIVADLVPLRESQKYMSMVMGTSALGTFVGPIIGGAI 100
                 689**************************...99****************************************************9998776 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   3.3   2.1e-06    0.0062     285     373 ..      13     100 ..       7     105 .] 0.94

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 2.1e-06
  MFS_1_like 285 eklGhvklliiallayilrfllyaiienawlvlpievLhgisfgllwaaaveyvskiapksleatgqgllsglyfglGralGsliGGll 373
                 +++G ++ lii++ ++il   l +  +n+ +++ i ++ g+  g l++++   v++++p +   ++++++ g+   lG+++G +iGG++
  EEA20002.1  13 DIFGKRVPLIISIAMFILGSGLCGGANNTAMLIHIKAFGGVGGGGLFVMVDIIVADLVPLRESQKYMSMVMGT-SALGTFVGPIIGGAI 100
                 68999999*************************************************************9998.89***********97 PP

>> MFS_2  MFS/sugar transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   3.7     2e-05     0.061     276     378 ..       5      98 ..       1     104 [. 0.75

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 2e-05
       MFS_2 276 iplwqplakrlgkkntyllgalltivllvlvlllqpsnlllflvllviagfgvgvaallpwsmladvvDygelktGkrregvffavlsfisklatgigl 374
                  pl   +   +gk+   ++++++ i+++ l+  +  +n+++++ + + +g+g g+++++++ ++ad+v   e          ++++++ +s l+t +g 
  EEA20002.1   5 QPLYRQASDIFGKRVPLIISIAMFILGSGLCGGA--NNTAMLIHIKAFGGVGGGGLFVMVDIIVADLVPLRE-------SQKYMSMVMGTSALGTFVGP 94 
                 5677777888999999999999999999888877..******************************994433.......44455555555555555555 PP

       MFS_2 375 gvsg 378
                 ++ g
  EEA20002.1  95 IIGG 98 
                 4444 PP

>> L6_membrane  L6 membrane protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   2.2     4e-05      0.12      26      99 ..      25      99 ..      15     105 .] 0.72

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 4e-05
  L6_membrane 26 illlfpngktey.lkeekiskevwlfgGilGgGllvllpaivilllgkkracscgnrckmllsillavlg.vlGal 99
                 i +++ +      +++  +  +++ fgG+ GgGl+v++  iv+ l+  +++ +   ++ m +s+l + +g ++G++
   EEA20002.1 25 IAMFILGSGLCGgANNTAMLIHIKAFGGVGGGGLFVMVDIIVADLVPLRES-QKYMSMVMGTSALGTFVGpIIGGA 99
                 55555554444446778888899**************99999999988874.356677777888888777544444 PP

>> Spore_III_AF  Stage III sporulation protein AF (Spore_III_AF)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.1   7.2e-05      0.22       3      42 ..      59      98 ..      58     104 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 7.2e-05
  Spore_III_AF  3 ivllatfvemlLPnkkmkkYvklvlGLllilailsPvlsl 42
                  +v++  +v  l+P  + +kY+ +v+G   + +++ P++++
    EEA20002.1 59 FVMVDIIVADLVPLRESQKYMSMVMGTSALGTFVGPIIGG 98
                  6777789999***************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (105 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       293  (0.0163422); expected 358.6 (0.02)
Passed bias filter:                      153  (0.00853366); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.47
# Mc/sec: 675.01
//
Query:       EEA20003.1  [L=486]
Description: dimethylaniline monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.9e-17   63.5   0.0    3.4e-16   59.4   0.0    2.1  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
    9.9e-13   47.3   0.0    7.6e-12   44.4   0.0    2.0  2  FMO-like       Flavin-binding monooxygenase-like
      1e-11   44.6   0.0    6.6e-11   41.9   0.0    1.9  2  K_oxygenase    L-lysine 6-monooxygenase (NADPH-requiring)
    4.3e-08   32.8   0.0    3.1e-06   26.6   0.0    2.2  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    2.6e-05   24.0   0.0    0.00028   20.6   0.0    2.4  3  DAO            FAD dependent oxidoreductase
  ------ inclusion threshold ------
      0.026   15.1   0.1       0.58   10.8   0.0    2.3  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
      0.041   13.9   0.0         11    6.0   0.0    2.7  2  NAD_binding_9  FAD-NAD(P)-binding


Domain annotation for each model (and alignments):
>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.4   0.0   1.3e-19   3.4e-16      74     198 ..      77     215 ..      24     241 .. 0.80
   2 ?    1.9   0.0     0.043   1.1e+02     215     274 ..     319     373 ..     309     396 .. 0.68

  Alignments for each domain:
  == domain 1  score: 59.4 bits;  conditional E-value: 1.3e-19
  Pyr_redox_3  74 keeklsrkealeYlrevaksfel..piklfeeVesvkk.edegfevetske......tyeAkkviiAtGefdkPnklnipGeek.lvk..hyskv.ke 158
                  ++e++ ++++ +Yl+ +a +f +  +i  +++V s+++  d+g ev++++e       y++kk+++AtG  ++Pn++ + G+e+ +v   h + + +e
   EEA20003.1  77 DNEHIPAATLHKYLTDYALKFGVfsRIVFNTHVLSIEQtRDDGWEVKAQSEgtkgeiIYQSKKIVMATGLTSQPNMPVFTGQESfNVPlfHAKDFcRE 174
                  5889999**************98778************67999***988765656678*************************843332233333323 PP

  Pyr_redox_3 159 fhkya.gqkvvViGgknSavDaAlelvrkgaeVtvvtrgse 198
                  ++ ++  ++v+V+Gg  Sa+D+A+ +v++ga+V +++r + 
   EEA20003.1 175 AAITKvANHVAVVGGAKSAFDIAYAFVQEGAQVDLIIRPNG 215
                  3333347899***************************9874 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.043
  Pyr_redox_3 215 enrleelvkeekikvlfnaevkeikekeeeykvktedgkkvevkddvvlatGykpd..lsfl 274
                   n + +l+k+++i+v++  e+++++e+    +v+ ++g+     d  + atG+k    ++fl
   EEA20003.1 319 TNFF-DLIKNGAIRVHEA-EINQLSER----TVHLSTGEL-LPADALICATGWKKGssVNFL 373
                  4444.5788888998887.55555553....677888755.556999*****9875224555 PP

>> FMO-like  Flavin-binding monooxygenase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.4   0.0     3e-15   7.6e-12      53     211 ..      48     209 ..      38     221 .. 0.83
   2 ?    0.2   0.0     0.077     2e+02     349     398 ..     420     469 ..     414     482 .. 0.77

  Alignments for each domain:
  == domain 1  score: 44.4 bits;  conditional E-value: 3e-15
    FMO-like  53 iyksvvsnsskemscfsdfplpedy.....pnflhnsklleylklfakefdllkyiqfkttvcsvkkrpdfstsGqwevvtekegkkesavfda..vmv 144
                 +y  + sn       ++d+p+ e        ++++   l +yl  +a +f+++  i f+t+v+s++++ d      wev +++eg k   ++++  +++
  EEA20003.1  48 LYPGLKSNNMLGSYEYPDYPMLEATygvkdNEHIPAATLHKYLTDYALKFGVFSRIVFNTHVLSIEQTRDD----GWEVKAQSEGTKGEIIYQSkkIVM 142
                 6666667777777789****99875122223466667789**************************99885....5***************98644777 PP

    FMO-like 145 ctGhhvnphlplesfpGiekfkGqyfhsrdykepevfk..gkrvlviGlGnsggdiavelsrtaeqvll 211
                  tG   +p++p+  f G e f   +fh++d+ + ++ +     v v+G   s+ dia    +  +qv l
  EEA20003.1 143 ATGLTSQPNMPV--FTGQESFNVPLFHAKDFCREAAITkvANHVAVVGGAKSAFDIAYAFVQEGAQVDL 209
                 99*********6..*****************988887623479***************99999999865 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.077
    FMO-like 349 vslykkvfpa.nlekptlaiiGliqplGsilptvelqarwavrvlkGlkkl 398
                 + ly+ + p+ +++k  +a  G + ++    + + +qa w+   + G  k 
  EEA20003.1 420 LRLYRFMVPTgTFQKRNIAFAGAVSTVS-TSTCASIQALWISAFFDGQLKR 469
                 67999999974689*********98875.556789**********996543 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.9   0.0   2.6e-14   6.6e-11      89     226 ..      77     214 ..      71     224 .. 0.84
   2 ?    0.2   0.0      0.13   3.3e+02     306     341 ..     333     365 ..     314     366 .. 0.70

  Alignments for each domain:
  == domain 1  score: 41.9 bits;  conditional E-value: 2.6e-14
  K_oxygenase  89 etflpsRkefedYlrWvasqle..eqvrfgeeveevepdeeeeeelltveskd.aegeeeelearnlvlgvG..tepkiPevleklegkervvHssey 181
                   +++++ +  ++Yl   a ++   +++ f+++v ++e+ +++    ++v+ ++  +  e  ++++++v+++G  ++p++P ++ + + +  ++H++++
   EEA20003.1  77 DNEHIPAATLHKYLTDYALKFGvfSRIVFNTHVLSIEQTRDD---GWEVKAQSeGTKGEIIYQSKKIVMATGltSQPNMPVFTGQESFNVPLFHAKDF 171
                  5677777888999999999988667799**********9986...46777644333335789**********8889******99999889******** PP

  K_oxygenase 182 lerkeellakkriaVvGsGqSaaeifedllrrqkkvelklvtrse 226
                   ++ + ++ ++++aVvG+ +Sa +i++  +++ +  +++l++r +
   EEA20003.1 172 CREAAITKVANHVAVVGGAKSAFDIAYAFVQEGA--QVDLIIRPN 214
                  ****99************************9988..788887765 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.13
  K_oxygenase 306 aeaegkgeveltlrneesgeeetlevdavvlATGYr 341
                   eae +   +l+ r  +  + e l +da+++ATG++
   EEA20003.1 333 HEAEIN---QLSERTVHLSTGELLPADALICATGWK 365
                  444433...6666666777889999*********97 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.6   0.0   1.2e-09   3.1e-06      57     172 ..      68     211 ..      14     218 .. 0.64
   2 ?    3.9   0.0      0.01        27      78     238 ..     340     365 ..     286     400 .. 0.60

  Alignments for each domain:
  == domain 1  score: 26.6 bits;  conditional E-value: 1.2e-09
                  H.......................HHHHCHHHHCCCCHCCTCEEEEESC.EEEEETEEEC..TCEEEEEESEEEE---..EEE-BCTCTTC.TTBEEC CS
                  x.......................xxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxx..xxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  57 s.......................evvkklnqgielllgeevvkidpgk.kkvklekkke..gdeekiaydklvlAtG..ssprdlgipGvaenvgkl 126
                                          +   k++   + + +++v++i++ +    ++++++e  + e  ++ +k+v+AtG  s+p+ +   G +  ++ l
   EEA20003.1  68 MleatygvkdnehipaatlhkyltDYALKFGVFSRIVFNTHVLSIEQTRdDGWEVKAQSEgtKGEIIYQSKKIVMATGltSQPNMPVFTGQESFNVPL 165
                  1555555555555555555555553333344344445556677776444333333333342255556666********87799999999**9999888 PP

                  CSECHHHHHHCCSS-TSEEEEES-SHHHHHHHHHHHHHT-EEEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 127 vrtldsaealklkllpkrivvvGgGyiGvElAaalaklgkevtlve 172
                   ++ d +++    ++ ++++vvGg   + ++A a+ + g++v l+ 
   EEA20003.1 166 FHAKDFCREAAITKVANHVAVVGGAKSAFDIAYAFVQEGAQVDLII 211
                  8888888888889999*************************99885 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.01
                  EEESCEEEEETEEECTCEEEEEESEEEE---EEE-BCTCTTC.TTBEECCSECHHHHHHCCSS-TSEEEEES-SHHHHHHHHHHHHHT-EEEEEESSS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  78 idpgkkkvklekkkegdeekiaydklvlAtGssprdlgipGvaenvgklvrtldsaealklkllpkrivvvGgGyiGvElAaalaklgkevtlveard 175
                  +   +++v+l     + +e + +d+l+ AtG                                                                   
   EEA20003.1 340 L--SERTVHL-----STGELLPADALICATGW------------------------------------------------------------------ 364
                  1..1123333.....55666666666666664.................................................................. PP

                  SSSTTS-HHHHHHHHHHHHHTTEEEEESCEEEEEEETTEEEEEEETTSCEEEESEEEE-S-EE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 176 rllraldkelsaaleealekeGvevklgtsvkeidgngeklevvledgeeidadlvvvavGvr 238
                                                                                +
   EEA20003.1 365 --------------------------------------------------------------K 365
                  ..............................................................2 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0      0.65   1.7e+03       8      36 ..      14      42 ..      14      47 .. 0.71
   2 !   20.6   0.0   1.1e-07   0.00028     133     207 ..      71     152 ..      25     247 .. 0.70
   3 ?    0.1   0.0      0.19   4.8e+02     156     203 ..     325     364 ..     300     393 .. 0.73

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.65
                SHHHHHHHHHHH.HTTEEEEESSSSTTSSG CS
         DAO  8 GiiGlstAyeLa.rrgVtllekgdiagsga 36
                Gi+ + t  +L  +++V++le+++ +g g+
  EEA20003.1 14 GITASKTYIQLHpEHKVLVLEAEKTCG-GT 42
                5666667777753444*******8888.66 PP

  == domain 2  score: 20.6 bits;  conditional E-value: 1.1e-07
                 EEEEETTEEEEEHHHHHHHHHHHHHHTT-..EEEESECEEEEEEEETCEEEEE...EECTEEE.EEEEEEEE--GGGHH.HH CS
         DAO 133 galfypdtgqvdpakltaalaraaealGv..eilegtevtgleeedgkvwgve...rttpgen.daadavVnaaGawsd.ll 207
                 + ++++d  ++ +a l ++l + a + Gv  +i+++t v ++e++++++w+v+   + t+ge+  + +++V+a+G+ s+  +
  EEA20003.1  71 ATYGVKDNEHIPAATLHKYLTDYALKFGVfsRIVFNTHVLSIEQTRDDGWEVKaqsEGTKGEIiYQSKKIVMATGLTSQpNM 152
                 44567787888888888888889*****999***********9988899***88774455444334377******9988644 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.19
                 HHHTT-EEEESECEEEEEEEETCEEEEEEECTEEEEEEEEEEE--GGG CS
         DAO 156 aealGveilegtevtgleeedgkvwgverttpgendaadavVnaaGaw 203
                 +++++++++e  e+  l+e+    +++   t ge   ada++ a+G w
  EEA20003.1 325 IKNGAIRVHEA-EINQLSER---TVHL--ST-GELLPADALICATG-W 364
                 44444566665.88888653...5555..44.766456*******9.4 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0      0.17   4.3e+02      43      78 ..      87     124 ..      83     128 .. 0.73
   2 ?   10.8   0.0   0.00023      0.58       1      30 [.     183     212 ..     183     222 .. 0.95

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.17
                 HHHHHHHHHHTTE..EEECSEEEEEEEEETTS.EEEEEE CS
   Pyr_redox  43 skilqeklekngi..evllntkveeiegsedg.vesvkl 78 
                  k+l+++  k g+  ++++nt v +ie++ d  +e vk 
  EEA20003.1  87 HKYLTDYALKFGVfsRIVFNTHVLSIEQTRDDgWE-VKA 124
                 566777777777655799*********87776566.765 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00023
                 EEEEECSSHHHHHHHHHHHHTTSEEEEEES CS
   Pyr_redox   1 kvvvvGgGyiglElAgalaelgkkVtvver 30 
                 +v+vvGg  ++ + A a+ + g++V ++ r
  EEA20003.1 183 HVAVVGGAKSAFDIAYAFVQEGAQVDLIIR 212
                 79************************9987 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.0    0.0097        25      84     154 ..      74     145 ..      12     147 .. 0.76
   2 ?    6.0   0.0    0.0041        11      99     154 ..     317     363 ..     312     365 .. 0.79

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0097
  NAD_binding_9  84 eldpddfvpRalyGrYlrdlfeellarlpegvtvevhraevvdleera.dgqavll....adgas.laadaVvLAlG 154
                    ++++++++p a + +Yl+d++ ++   ++      v++++v+++e+++ dg++v      ++g+  ++ +++v+A+G
     EEA20003.1  74 GVKDNEHIPAATLHKYLTDYALKFGV-FS----RIVFNTHVLSIEQTRdDGWEVKAqsegTKGEIiYQSKKIVMATG 145
                    56788888888888999998888873.33....3467889999988662556666632223344346999*****99 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.0041
  NAD_binding_9  99 YlrdlfeellarlpegvtvevhraevvdleeradgqavlladgaslaadaVvLAlG 154
                    Y++++f+ + +       ++vh+ae+ +l+er    +v+l++g+ l ada++ A+G
     EEA20003.1 317 YQTNFFDLIKNG-----AIRVHEAEINQLSER----TVHLSTGELLPADALICATG 363
                    555555554443.....489999999999876....899****************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (486 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       389  (0.0216967); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.43
# Mc/sec: 3356.34
//
Query:       EEA20004.1  [L=663]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.5e-06   27.0  10.6    7.4e-06   26.0  10.6    1.5  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
      6e-06   25.5   0.0    1.1e-05   24.6   0.0    1.3  1  Fungal_trans    Fungal specific transcription factor domain
  ------ inclusion threshold ------
      0.044   13.3   0.0      0.076   12.6   0.0    1.3  1  Glyco_hydro_cc  Glycosyl hydrolase catalytic core


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0  10.6   1.2e-09   7.4e-06       1      28 [.      16      44 ..      16      51 .. 0.89

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 1.2e-09
                SS-HHHHHCT---STSSSS-HHHHHCT..H CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkkln..l 28
                +aC +Cr  K KCd ++P C++C+ ++   
  EEA20004.1 16 TACVQCRVSKKKCDSRQP-CQKCVAKGepD 44
                69****************.*****998555 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.6   0.0   1.8e-09   1.1e-05      32     173 ..     208     334 ..     187     345 .. 0.85

  Alignments for each domain:
  == domain 1  score: 24.6 bits;  conditional E-value: 1.8e-09
  Fungal_trans  32 sayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLlllelyektssdralherhhgvavrlarslg 128
                      ++++ll +++a+Ga+++  ++  ++         +++f  ++ i +  +   +++ ++   ++ l++++ ++ ++r+ + +++g+a ++++ lg
    EEA20004.1 208 PETNHDILLDLMIAIGAQCQARTNTDNHVA-------MLHFKRAQIIAF--SDMLQAPTVNLARAFALMAFFMLGACNRNPALMYVGIASNISVILG 295
                   445999************999999998333.......566666666777..5555555579999********************************* PP

  Fungal_trans 129 LhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrp 173
                   Lh  +sy +      l++e++e+r  +  ++ +lD ++ ++lGrp
    EEA20004.1 296 LHSPESYQQ------LPVEKREARLQTGKSIRVLDLICNTILGRP 334
                   *******99......*********999999999999999999998 PP

>> Glyco_hydro_cc  Glycosyl hydrolase catalytic core
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   1.3e-05     0.076      50      93 ..     554     611 ..     530     651 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.3e-05
  Glyco_hydro_cc  50 ksadtdalanvksa........akenskylLgFNePDlks......qsnmspeeAakl 93 
                      s+ +da+an+++         +++n++ +L+F+eP+ ++      q+nmsp++ a+ 
      EEA20004.1 554 LSNFADAIANYQRKsrmkrlrlENSNVERILAFDEPNDQQpvafqtQTNMSPSRVASV 611
                     5555666666666677777788899************988899999*******99875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (663 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       786  (0.0438396); expected 358.6 (0.02)
Passed bias filter:                      558  (0.0311228); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.69u 0.34s 00:00:01.03 Elapsed: 00:00:00.51
# Mc/sec: 3896.76
//
Query:       EEA20005.1  [L=321]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.1e-57  193.9   0.0    3.7e-57  193.6   0.0    1.0  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
    7.2e-47  159.4   0.0    9.4e-47  159.0   0.0    1.1  1  adh_short     short chain dehydrogenase
    6.6e-14   52.2   0.0    9.9e-14   51.6   0.0    1.3  1  KR            KR domain
      0.002   18.6   0.0     0.0043   17.6   0.0    1.6  1  HATPase_c     Histidine kinase-, DNA gyrase B-, and HSP90-lik
  ------ inclusion threshold ------
      0.032   13.3   0.0      0.065   12.2   0.0    1.4  1  3Beta_HSD     3-beta hydroxysteroid dehydrogenase/isomerase f
       0.15   11.3   0.0       0.24   10.6   0.0    1.2  1  DUF43         Branched-chain polyamine synthase A C-terminal 


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  193.6   0.0   1.2e-60   3.7e-57       1     234 []      68     308 ..      68     308 .. 0.94

  Alignments for each domain:
  == domain 1  score: 193.6 bits;  conditional E-value: 1.2e-60
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSE.E.EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHH CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneeakkrveelaeelgae.v.lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreef 95 
                   G a+gIG+a+ +a+ae G +v++ d++++   + ++l +++g++ + +++DV+ e+++ +++++v+e+f+++D+lv +agia +  +pf+e +++ef
    EEA20005.1  68 GGAQGIGFAVTRAIAEMGGNVAVLDIQDSPVPEFHSLSQKFGTRlLyIKTDVRIEASIFEAFAKVEETFKTIDGLVPAAGIAID--KPFIEQTWDEF 162
                   669***************************99************637*************************************..*********** PP

                   HHHHHHHTHHHHHHHHHHHH.HCTSC..CEEEEEEEGGGTSBSTTTT..HHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTTHHH CS
  adh_short_C2  96 draldvnlyslfllakaalp.lmkeg..gsivnlssvgaervvpnyn..aygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikgfde 187
                    r+ ++n++++f +++ + + l+k+g  gs+v ++s +a++++p+y   +y+a+K+a+  ++++lAvel+p++iRvN++spg+++ +++++++ +++
    EEA20005.1 163 TRINEINVRGTFFICQMLTKhLIKQGrpGSMVLIASQSAHIALPGYRmaVYNASKGAVLMFSKALAVELAPYNIRVNTISPGFVDSDMTRNVRASKS 259
                   ********************8888889*******************999******************************************998555 PP

                   .HH.HHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEESTTGG CS
  adh_short_C2 188 .ll.eelearaplgrlgtpeevaeaalfLasdeasyitGqtlvvDgGlt 234
                    ++ +++    p++rl t+++   a+++L+sd+a+++t +++ + gGl+
    EEA20005.1 260 kMEgQQMWLAPPMRRLSTQNDLTGAVIYLLSDAAQFTTAADIPITGGLH 308
                   133133455678***********************************98 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  159.0   0.0   3.2e-50   9.4e-47       4     193 ..      65     257 ..      62     259 .. 0.95

  Alignments for each domain:
  == domain 1  score: 159.0 bits;  conditional E-value: 3.2e-50
                 EEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCSHHHHH CS
   adh_short   4 lvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfselseeewe 102
                 +vtG+++GIG a+ +++a++G +v+v+d++++++ e ++  ++ g+++l+i++Dv+ ++++ ++++k+++ ++++d Lv  AGi+ ++pf e + +e+ 
  EEA20005.1  65 IVTGGAQGIGFAVTRAIAEMGGNVAVLDIQDSPVPEFHSLSQKFGTRLLYIKTDVRIEASIFEAFAKVEETFKTIDGLVPAAGIAIDKPFIEQTWDEFT 163
                 8*********************************9999988888******************************************************* PP

                 HHHHHHTHHHHHHHHHHHHHHH.HCTTEEEEEEEEGGGTSB-T..TBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHHCTH CS
   adh_short 103 rvievNltgvflltravlpaml.kqssGrIvnvsSvagkvpva..gvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakelrek 193
                 r+ e+N+ g+f ++++++++++ +++ G+ v ++S+ ++ +++   +a+Y AsK+av +++++la elap++irvn++ PG+vd+dm++++r+ 
  EEA20005.1 164 RINEINVRGTFFICQMLTKHLIkQGRPGSMVLIASQSAHIALPgyRMAVYNASKGAVLMFSKALAVELAPYNIRVNTISPGFVDSDMTRNVRAS 257
                 ********************9977889***********7766511689*****************************************99875 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.6   0.0   3.3e-17   9.9e-14       2     144 ..      63     206 ..      62     225 .. 0.84

  Alignments for each domain:
  == domain 1  score: 51.6 bits;  conditional E-value: 3.3e-17
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHT.T-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaeleal.gaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdkllee 99 
                 +y++tGG+ g+G +++r +ae g +  vl   + +  +    ++++l+++ g++  +++ Dv  ++++ ++++++++++++i G + aAg++ dk++ e
  EEA20005.1  63 SYIVTGGAQGIGFAVTRAIAEMGGNVAVLDIQD-S--P-VP-EFHSLSQKfGTRLLYIKTDVRIEASIFEAFAKVEETFKTIDGLVPAAGIAIDKPFIE 156
                 6**********************8776665555.2..2.33.244555555************************************************ PP

                 --HHHHHHHHTTTTHHHHHHHHHTTT.....S--SEEEEEEEHHHHH--T CS
          KR 100 mtaedleqvlapKvkGawnLhelled.....esldffvlfSSiagllgsa 144
                 +t ++++++ +  v+G+  + ++l++      +   +vl++S ++ +  +
  EEA20005.1 157 QTWDEFTRINEINVRGTFFICQMLTKhlikqGRPGSMVLIASQSAHIALP 206
                 *****************988877766555446777888888888876655 PP

>> HATPase_c  Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   1.4e-06    0.0043      56      95 ..      49      98 ..      15     124 .. 0.74

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 1.4e-06
                GTCS..TTCH..HCSTCHTSTSSSHHHHHHHHHHHHTTTEEEE.......E CS
   HATPase_c 56 klfe..kfsq..ddstkrggggtGlGlsivkklvelmgGeiwv.......e 95
                +lf+  +f++   +s+ ++gg  G+G+++ ++++e mgG++ v        
  EEA20005.1 49 RLFTksSFTDlkGRSYIVTGGAQGIGFAVTRAIAE-MGGNVAVldiqdspV 98
                78877667779989*********************.****99977654440 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   2.2e-05     0.065       1     106 [.      65     183 ..      65     187 .. 0.68

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2.2e-05
   3Beta_HSD   1 vvtGgaGFlGralvkeLvrleelkevrvlDlresp..elleelskvnvkk.viegDvtdkdkleealegvdvvihl.aslvdvag.k..........lt 84 
                 +vtGga  +G a+ +++ +++   +v vlD+++sp  e ++ ++k++++  +i++Dv+ ++++ ea  +v+  + +  +lv+ ag            ++
  EEA20005.1  65 IVTGGAQGIGFAVTRAIAEMG--GNVAVLDIQDSPvpEFHSLSQKFGTRLlYIKTDVRIEASIFEAFAKVEETFKTiDGLVPAAGiAidkpfieqtwDE 161
                 69******************9..59*******9962266777888888879*******99999999888776665423333333311111111111134 PP

   3Beta_HSD  85 edeimkvnvkGTrnvleacvka 106
                 + +i ++nv+GT  + ++ +k+
  EEA20005.1 162 FTRINEINVRGTFFICQMLTKH 183
                 5567777777777776666655 PP

>> DUF43  Branched-chain polyamine synthase A C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   7.9e-05      0.24      38     103 ..      54     121 ..      44     151 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 7.9e-05
                 HHTT-STT-EEEEES-TT-HHHHH..HHHT--SEEEEE-S-HHHHHHHHHHHHHHT--EEEE---TTS CS
       DUF43  38 yerGDLegkeilvlGdDDLtslal..aLtglpkkvvvvDiDeRlikfiervakelglkieaivyDlrk 103
                  +  DL+g+  +v G    ++ a+  a++++  +v+v+Di +  +   + ++++ g  +  i+ D+r 
  EEA20005.1  54 SSFTDLKGRSYIVTGGAQGIGFAVtrAIAEMGGNVAVLDIQDSPVPEFHSLSQKFGTRLLYIKTDVRI 121
                 5678***********88877766533899***********9999999999*******99999999984 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (321 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       431  (0.0240393); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 2149.02
//
Query:       EEA20006.1  [L=146]
Description: hypothetical protein PMAA_007730 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.7e-07   30.9   0.1      4e-07   30.4   0.1    1.3  1  Helicase_C  Helicase conserved C-terminal domain


Domain annotation for each model (and alignments):
>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.4   0.1   2.2e-11     4e-07      18     110 ..      28     133 ..      20     134 .. 0.70

  Alignments for each domain:
  == domain 1  score: 30.4 bits;  conditional E-value: 2.2e-11
                 EEEEEESSHHHHHH......HHHHHHHT...TSTEEEESTTSTHHHHHHHHHHHH..TTSSSEEEESGGGTSSSTSTTESEEEESSSS..SSHHHHHHH CS
  Helicase_C  18 kilifvntidrlek......vklllekk...gikvavlhgelpqnereeileqfn..kgesdvLiatdvaerGidipkvnlVinfdlp..rnvtsyiqr 103
                 k++if+   + l        +++l ek       + ++  +    ++++++++f+  k +++++ a + ++ G++i +v++Vi   +p  +n+ +  q 
  EEA20006.1  28 KMIIFIDDLEVLTYillrknADILDEKAvriTKVIRPYFTRGAEYDKDQTFAEFKdeKSKTRIIFAITSLGIGVNIIDVKYVIYWRFPisFNMLDTYQK 126
                 566666666644211222233344333344322233333345667889*******7666777************************999899******* PP

                 HTTSSST CS
  Helicase_C 104 iGRtgRa 110
                 +GR gR+
  EEA20006.1 127 AGRGGRG 133
                 ******6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (146 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       374  (0.0208601); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.44
# Mc/sec: 997.96
//
Query:       EEA20007.1  [L=152]
Description: hypothetical protein PMAA_007740 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
     0.0024   18.0   5.8     0.0037   17.4   5.8    1.3  1  Nup54       Nucleoporin complex subunit 54
  ------ inclusion threshold ------
       0.18    9.7   0.9       0.19    9.6   0.9    1.0  1  V_ATPase_I  V-type ATPase 116kDa subunit family
       0.38    9.6   7.9        0.5    9.2   7.9    1.0  1  Spc7        Spc7 kinetochore protein
        1.3    9.6   4.9        4.1    8.0   1.2    2.3  2  TipAS       TipAS antibiotic-recognition domain
        3.1    8.0  11.3       0.35   11.0   5.7    2.0  2  DMPK_coil   DMPK coiled coil domain like


Domain annotation for each model (and alignments):
>> Nup54  Nucleoporin complex subunit 54
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   5.8     1e-06    0.0037      60     135 ..      29     121 ..      23     126 .. 0.73

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 1e-06
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-SS---S................SHHHHHHHHHHHHHHHS-H..HH.HHHHHH CS
       Nup54  60 eeleqkhqletsvrlekakkrhvelshRllrllrkleilrsrgyalda................eEeelrarletleaqlndp..aqlkgrvne 135
                 ++l+ + ++++s +l +a ++++els ++ rl+r++e l+ rg +++                 e e ++a  e + +ql+++  a  +  ++e
  EEA20007.1  29 NKLK-ESEQKISRELSEALSQQAELSAKIARLFRQQEFLKERGVNMKShnqkvleildsenpptEAEVAAADAEIMREQLESHvlAATSEELDE 121
                 5666.78899**********************************99886666666666666666555555555555555555444444555555 PP

>> V_ATPase_I  V-type ATPase 116kDa subunit family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.9   5.3e-05      0.19      63     135 ..      20      92 ..       2     142 .. 0.69

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 5.3e-05
  V_ATPase_I  63 leapeekeldeleeelekleeelkelnenleklkkelnelvelkavlekakefleeeeeeeeeeeseeeeeek 135
                 ++ ++e+e ++l+e+ +k+ +el+e  +++ +l+++  +l  +++ l++    +++++++  e  ++e+  ++
  EEA20007.1  20 RRFHSEREWNKLKESEQKISRELSEALSQQAELSAKIARLFRQQEFLKERGVNMKSHNQKVLEILDSENPPTE 92 
                 556789999**************************************99999998774444443332222221 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   7.9   0.00014       0.5     145     243 ..      25     123 ..      22     128 .. 0.93

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00014
        Spc7 145 eenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqk 243
                 e++ ++l+e +++++++ +e+ +   el+++ a+l ++ e l+e+  +++s +++ Le l +e    +ae+++  +e+ + q +   l+++ eel+e  
  EEA20007.1  25 EREWNKLKESEQKISRELSEALSQQAELSAKIARLFRQQEFLKERGVNMKSHNQKVLEILDSENPPTEAEVAAADAEIMREQLESHVLAATSEELDELF 123
                 66778999***************************************************************************9999999999998865 PP

>> TipAS  TipAS antibiotic-recognition domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   1.2    0.0012       4.1      26      63 ..      24      60 ..      19      69 .. 0.76
   2 ?    2.8   0.3     0.047   1.7e+02      37      71 ..      73     108 ..      61     132 .. 0.53

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0012
                XXXXXXXXXXXXXXXXXXXXXX..XXXXXXXXXXXXXX CS
       TipAS 26 skedweelkaelkelfaklaaalaagkdpdseeaqela 63
                s+ +w++lk+ ++++ ++l +al+++ +  s+++ +l+
  EEA20007.1 24 SEREWNKLKESEQKISRELSEALSQQ-AELSAKIARLF 60
                7899******************9544.45555555555 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.047
                 XXXXXXXXXXX..XXXXXXXXXXXXXXXX.XXXXXX CS
       TipAS  37 lkelfaklaaalaagkdpdseeaqelaee.hralie 71 
                 +k  ++k+ + l+++ +p+ +e+ ++ +e +r+ +e
  EEA20007.1  73 MKSHNQKVLEILDSENPPTEAEVAAADAEiMREQLE 108
                 555666666777777777777776653330333333 PP

>> DMPK_coil  DMPK coiled coil domain like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   5.7   9.7e-05      0.35      18      59 ..      26      67 ..      23      69 .. 0.92
   2 ?   -0.4   0.3      0.36   1.3e+03       7      47 ..      99     110 ..      91     124 .. 0.57

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 9.7e-05
   DMPK_coil 18 eeLekvkaanlafeskLkeaEkknreLeeeleqLkkemEelr 59
                +e +k k+++++ ++ L ea ++  eL +++++L ++ E l+
  EEA20007.1 26 REWNKLKESEQKISRELSEALSQQAELSAKIARLFRQQEFLK 67
                799*******************************99988776 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.36
   DMPK_coil   7 eaEirakQslqeeLekvkaanlafeskLkeaEkknreLeee 47 
                 +                             aE    +Le++
  EEA20007.1  99 D-----------------------------AEIMREQLESH 110
                 3.............................44444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (152 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1672  (0.0932567); expected 358.6 (0.02)
Passed bias filter:                      859  (0.0479112); expected 358.6 (0.02)
Passed Vit filter:                        89  (0.00496402); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 1018.51
//
Query:       EEA20008.1  [L=152]
Description: hypothetical protein PMAA_007740 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
     0.0024   18.0   5.8     0.0037   17.4   5.8    1.3  1  Nup54       Nucleoporin complex subunit 54
  ------ inclusion threshold ------
       0.18    9.7   0.9       0.19    9.6   0.9    1.0  1  V_ATPase_I  V-type ATPase 116kDa subunit family
       0.38    9.6   7.9        0.5    9.2   7.9    1.0  1  Spc7        Spc7 kinetochore protein
        1.3    9.6   4.9        4.1    8.0   1.2    2.3  2  TipAS       TipAS antibiotic-recognition domain
        3.1    8.0  11.3       0.35   11.0   5.7    2.0  2  DMPK_coil   DMPK coiled coil domain like


Domain annotation for each model (and alignments):
>> Nup54  Nucleoporin complex subunit 54
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   5.8     1e-06    0.0037      60     135 ..      29     121 ..      23     126 .. 0.73

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 1e-06
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-SS---S................SHHHHHHHHHHHHHHHS-H..HH.HHHHHH CS
       Nup54  60 eeleqkhqletsvrlekakkrhvelshRllrllrkleilrsrgyalda................eEeelrarletleaqlndp..aqlkgrvne 135
                 ++l+ + ++++s +l +a ++++els ++ rl+r++e l+ rg +++                 e e ++a  e + +ql+++  a  +  ++e
  EEA20008.1  29 NKLK-ESEQKISRELSEALSQQAELSAKIARLFRQQEFLKERGVNMKShnqkvleildsenpptEAEVAAADAEIMREQLESHvlAATSEELDE 121
                 5666.78899**********************************99886666666666666666555555555555555555444444555555 PP

>> V_ATPase_I  V-type ATPase 116kDa subunit family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.9   5.3e-05      0.19      63     135 ..      20      92 ..       2     142 .. 0.69

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 5.3e-05
  V_ATPase_I  63 leapeekeldeleeelekleeelkelnenleklkkelnelvelkavlekakefleeeeeeeeeeeseeeeeek 135
                 ++ ++e+e ++l+e+ +k+ +el+e  +++ +l+++  +l  +++ l++    +++++++  e  ++e+  ++
  EEA20008.1  20 RRFHSEREWNKLKESEQKISRELSEALSQQAELSAKIARLFRQQEFLKERGVNMKSHNQKVLEILDSENPPTE 92 
                 556789999**************************************99999998774444443332222221 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   7.9   0.00014       0.5     145     243 ..      25     123 ..      22     128 .. 0.93

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00014
        Spc7 145 eenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqk 243
                 e++ ++l+e +++++++ +e+ +   el+++ a+l ++ e l+e+  +++s +++ Le l +e    +ae+++  +e+ + q +   l+++ eel+e  
  EEA20008.1  25 EREWNKLKESEQKISRELSEALSQQAELSAKIARLFRQQEFLKERGVNMKSHNQKVLEILDSENPPTEAEVAAADAEIMREQLESHVLAATSEELDELF 123
                 66778999***************************************************************************9999999999998865 PP

>> TipAS  TipAS antibiotic-recognition domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   1.2    0.0012       4.1      26      63 ..      24      60 ..      19      69 .. 0.76
   2 ?    2.8   0.3     0.047   1.7e+02      37      71 ..      73     108 ..      61     132 .. 0.53

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0012
                XXXXXXXXXXXXXXXXXXXXXX..XXXXXXXXXXXXXX CS
       TipAS 26 skedweelkaelkelfaklaaalaagkdpdseeaqela 63
                s+ +w++lk+ ++++ ++l +al+++ +  s+++ +l+
  EEA20008.1 24 SEREWNKLKESEQKISRELSEALSQQ-AELSAKIARLF 60
                7899******************9544.45555555555 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.047
                 XXXXXXXXXXX..XXXXXXXXXXXXXXXX.XXXXXX CS
       TipAS  37 lkelfaklaaalaagkdpdseeaqelaee.hralie 71 
                 +k  ++k+ + l+++ +p+ +e+ ++ +e +r+ +e
  EEA20008.1  73 MKSHNQKVLEILDSENPPTEAEVAAADAEiMREQLE 108
                 555666666777777777777776653330333333 PP

>> DMPK_coil  DMPK coiled coil domain like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   5.7   9.7e-05      0.35      18      59 ..      26      67 ..      23      69 .. 0.92
   2 ?   -0.4   0.3      0.36   1.3e+03       7      47 ..      99     110 ..      91     124 .. 0.57

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 9.7e-05
   DMPK_coil 18 eeLekvkaanlafeskLkeaEkknreLeeeleqLkkemEelr 59
                +e +k k+++++ ++ L ea ++  eL +++++L ++ E l+
  EEA20008.1 26 REWNKLKESEQKISRELSEALSQQAELSAKIARLFRQQEFLK 67
                799*******************************99988776 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.36
   DMPK_coil   7 eaEirakQslqeeLekvkaanlafeskLkeaEkknreLeee 47 
                 +                             aE    +Le++
  EEA20008.1  99 D-----------------------------AEIMREQLESH 110
                 3.............................44444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (152 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1672  (0.0932567); expected 358.6 (0.02)
Passed bias filter:                      859  (0.0479112); expected 358.6 (0.02)
Passed Vit filter:                        89  (0.00496402); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 1073.53
//
Query:       EEA20009.1  [L=152]
Description: hypothetical protein PMAA_007740 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
     0.0024   18.0   5.8     0.0037   17.4   5.8    1.3  1  Nup54       Nucleoporin complex subunit 54
  ------ inclusion threshold ------
       0.18    9.7   0.9       0.19    9.6   0.9    1.0  1  V_ATPase_I  V-type ATPase 116kDa subunit family
       0.38    9.6   7.9        0.5    9.2   7.9    1.0  1  Spc7        Spc7 kinetochore protein
        1.3    9.6   4.9        4.1    8.0   1.2    2.3  2  TipAS       TipAS antibiotic-recognition domain
        3.1    8.0  11.3       0.35   11.0   5.7    2.0  2  DMPK_coil   DMPK coiled coil domain like


Domain annotation for each model (and alignments):
>> Nup54  Nucleoporin complex subunit 54
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   5.8     1e-06    0.0037      60     135 ..      29     121 ..      23     126 .. 0.73

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 1e-06
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-SS---S................SHHHHHHHHHHHHHHHS-H..HH.HHHHHH CS
       Nup54  60 eeleqkhqletsvrlekakkrhvelshRllrllrkleilrsrgyalda................eEeelrarletleaqlndp..aqlkgrvne 135
                 ++l+ + ++++s +l +a ++++els ++ rl+r++e l+ rg +++                 e e ++a  e + +ql+++  a  +  ++e
  EEA20009.1  29 NKLK-ESEQKISRELSEALSQQAELSAKIARLFRQQEFLKERGVNMKShnqkvleildsenpptEAEVAAADAEIMREQLESHvlAATSEELDE 121
                 5666.78899**********************************99886666666666666666555555555555555555444444555555 PP

>> V_ATPase_I  V-type ATPase 116kDa subunit family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.9   5.3e-05      0.19      63     135 ..      20      92 ..       2     142 .. 0.69

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 5.3e-05
  V_ATPase_I  63 leapeekeldeleeelekleeelkelnenleklkkelnelvelkavlekakefleeeeeeeeeeeseeeeeek 135
                 ++ ++e+e ++l+e+ +k+ +el+e  +++ +l+++  +l  +++ l++    +++++++  e  ++e+  ++
  EEA20009.1  20 RRFHSEREWNKLKESEQKISRELSEALSQQAELSAKIARLFRQQEFLKERGVNMKSHNQKVLEILDSENPPTE 92 
                 556789999**************************************99999998774444443332222221 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   7.9   0.00014       0.5     145     243 ..      25     123 ..      22     128 .. 0.93

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00014
        Spc7 145 eenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqk 243
                 e++ ++l+e +++++++ +e+ +   el+++ a+l ++ e l+e+  +++s +++ Le l +e    +ae+++  +e+ + q +   l+++ eel+e  
  EEA20009.1  25 EREWNKLKESEQKISRELSEALSQQAELSAKIARLFRQQEFLKERGVNMKSHNQKVLEILDSENPPTEAEVAAADAEIMREQLESHVLAATSEELDELF 123
                 66778999***************************************************************************9999999999998865 PP

>> TipAS  TipAS antibiotic-recognition domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   1.2    0.0012       4.1      26      63 ..      24      60 ..      19      69 .. 0.76
   2 ?    2.8   0.3     0.047   1.7e+02      37      71 ..      73     108 ..      61     132 .. 0.53

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0012
                XXXXXXXXXXXXXXXXXXXXXX..XXXXXXXXXXXXXX CS
       TipAS 26 skedweelkaelkelfaklaaalaagkdpdseeaqela 63
                s+ +w++lk+ ++++ ++l +al+++ +  s+++ +l+
  EEA20009.1 24 SEREWNKLKESEQKISRELSEALSQQ-AELSAKIARLF 60
                7899******************9544.45555555555 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.047
                 XXXXXXXXXXX..XXXXXXXXXXXXXXXX.XXXXXX CS
       TipAS  37 lkelfaklaaalaagkdpdseeaqelaee.hralie 71 
                 +k  ++k+ + l+++ +p+ +e+ ++ +e +r+ +e
  EEA20009.1  73 MKSHNQKVLEILDSENPPTEAEVAAADAEiMREQLE 108
                 555666666777777777777776653330333333 PP

>> DMPK_coil  DMPK coiled coil domain like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   5.7   9.7e-05      0.35      18      59 ..      26      67 ..      23      69 .. 0.92
   2 ?   -0.4   0.3      0.36   1.3e+03       7      47 ..      99     110 ..      91     124 .. 0.57

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 9.7e-05
   DMPK_coil 18 eeLekvkaanlafeskLkeaEkknreLeeeleqLkkemEelr 59
                +e +k k+++++ ++ L ea ++  eL +++++L ++ E l+
  EEA20009.1 26 REWNKLKESEQKISRELSEALSQQAELSAKIARLFRQQEFLK 67
                799*******************************99988776 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.36
   DMPK_coil   7 eaEirakQslqeeLekvkaanlafeskLkeaEkknreLeee 47 
                 +                             aE    +Le++
  EEA20009.1  99 D-----------------------------AEIMREQLESH 110
                 3.............................44444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (152 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1672  (0.0932567); expected 358.6 (0.02)
Passed bias filter:                      859  (0.0479112); expected 358.6 (0.02)
Passed Vit filter:                        89  (0.00496402); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 1101.05
//
Query:       EEA20010.1  [L=176]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-15   56.5   0.0    5.1e-15   56.0   0.0    1.3  1  HsbA      Hydrophobic surface binding protein A


Domain annotation for each model (and alignments):
>> HsbA  Hydrophobic surface binding protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.0   0.0   2.8e-19   5.1e-15      10     118 ..      42     145 ..      33     147 .. 0.89

  Alignments for each domain:
  == domain 1  score: 56.0 bits;  conditional E-value: 2.8e-19
                 HHHHHHHHHHHHHHH--S.H...HHHHHHHHHHHHHHHHHHHHHHHTS----HHHHHHHHHHHHHCHHHHHHHHHHHHHTHHHHHHHT-HHHHHHHHHH CS
        HsbA  10 tistavtaldtavnafnG.g.asalpilsasnalvsaikkattdaqasapltdeealalaqavqtLepdvkaaldaliaKkpafdkagltslvlssLqd 106
                 +i         av++f++   + +  i  +++ +++ai++++    + +plt+ ea al+ +   L+ +v+ al +li K+  + +agl+++v ++L++
  EEA20010.1  42 DI-------RLAVDKFKNdIfLAIPDIPGDFDVIINAIQQGMGRLGTEPPLTPFEARALIIPSMPLKEHVEEALRNLIGKRGIMVTAGLKPQVAQDLRR 133
                 44.......44566665543455899************************************************************************* PP

                 HHHHHHHHHHHH CS
        HsbA 107 lkaasdaLsdal 118
                 lkaa+++Ls  +
  EEA20010.1 134 LKAAAEQLSSIV 145
                 *********877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (176 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       380  (0.0211947); expected 358.6 (0.02)
Passed bias filter:                      349  (0.0194657); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.28s 00:00:00.71 Elapsed: 00:00:00.44
# Mc/sec: 1202.68
//
Query:       EEA20011.1  [L=58]
Description: hypothetical protein PMAA_007760 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (58 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       392  (0.021864); expected 358.6 (0.02)
Passed bias filter:                      267  (0.0148921); expected 358.6 (0.02)
Passed Vit filter:                         5  (0.000278878); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.33u 0.25s 00:00:00.58 Elapsed: 00:00:00.39
# Mc/sec: 449.02
//
Query:       EEA20012.1  [L=220]
Description: hypothetical protein PMAA_007770 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.7e-19   68.3   0.3    1.1e-18   67.8   0.3    1.3  1  HsbA           Hydrophobic surface binding protein A
  ------ inclusion threshold ------
       0.16   11.7   0.0       0.26   11.0   0.0    1.3  1  Dimer_Tnp_Tn5  Transposase Tn5 dimerisation domain


Domain annotation for each model (and alignments):
>> HsbA  Hydrophobic surface binding protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.8   0.3   1.2e-22   1.1e-18       7     117 ..      38     152 ..      32     155 .. 0.95

  Alignments for each domain:
  == domain 1  score: 67.8 bits;  conditional E-value: 1.2e-22
                 HHHHHHHHHHHHHHHHHH--SH..HHHHHHHHHHHHHHHHHHHH..HHHTS----HHHHHHHHHHHHH...CHHHHHHHHHHHHHTHHHHHHHT-HHHH CS
        HsbA   7 dittistavtaldtavnafnGgasalpilsasnalvsaikkatt..daqasapltdeealalaqavqt...LepdvkaaldaliaKkpafdkagltslv 100
                 +i+ i+t +++++t +++++Gg ++ +il+ +n++++ +k ++t  d q++ plt +e l+l++++++   Le+  k a+++li Kk+ +  +gl+s  
  EEA20012.1  38 VINIINTTTSDFNTRIQSYQGG-DLSSILEGCNQVTQIMKLGATilDQQTTKPLTNNEWLSLLSHMEKkggLEDMLKMAINTLILKKSLILDSGLGSKL 135
                 7888*****************5.8********************99*********************6699**************************** PP

                 HHHHHHHHHHHHHHHHH CS
        HsbA 101 lssLqdlkaasdaLsda 117
                    L ++++as +L++ 
  EEA20012.1 136 GLALYSQQMASIDLGAK 152
                 **************986 PP

>> Dimer_Tnp_Tn5  Transposase Tn5 dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   2.9e-05      0.26       7      43 ..      72     108 ..      68     131 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 2.9e-05
  Dimer_Tnp_Tn5   7 rrlkelaeaveeldaelvleqdewrilylnlnkrggr 43 
                     ++++l+ ++ ++++++ l+++ew  l   ++k+gg 
     EEA20012.1  72 TQIMKLGATILDQQTTKPLTNNEWLSLLSHMEKKGGL 108
                    679*************************99***9985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (220 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       385  (0.0214736); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.41
# Mc/sec: 1596.86
//
Query:       EEA20013.1  [L=786]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    6.6e-10   39.4   0.2      2e-09   37.9   0.2    1.8  1  OrsD        Orsellinic acid/F9775 biosynthesis cluster protei
     0.0079   15.8   0.0       0.11   12.1   0.0    2.5  2  zf-C2H2_12  Zinc-finger C2H2-type
  ------ inclusion threshold ------
      0.033   14.2   2.9      0.056   13.5   0.9    2.5  2  zf-BED      BED zinc finger


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.9   0.2   3.4e-13     2e-09       8     114 .]      21     116 ..      17     116 .. 0.89

  Alignments for each domain:
  == domain 1  score: 37.9 bits;  conditional E-value: 3.4e-13
        OrsD   8 eyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgLpvyeGyrCrakakC.kyltrslktl 105
                 ++r+liC++C +a+ p+++++H  ++h+    e+++ l e++      rq d   +e++ v +++      p L +y+G+ C     C +y t +l++l
  EEA20013.1  21 NFRLLICESCGFALGPNQASSHFWEKHQVS-VEQRHGLTEYL------RQHD--FQEPASVAPRPRGASEHPALRTYNGLAC---RLCeTYYTINLDNL 107
                 5799********************998887.666899**999......8888..789999999999999999**********...56736********* PP

        OrsD 106 rkHlqkkhg 114
                  kHl+++h+
  EEA20013.1 108 LKHLRHQHP 116
                 ******995 PP

>> zf-C2H2_12  Zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0     0.084     5e+02      19      38 ..      21      40 ..      11      65 .. 0.68
   2 !   12.1   0.0   1.9e-05      0.11      21      55 ..      89     122 ..      86     132 .. 0.85

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.084
  zf-C2H2_12 19 qrrglvCmvCgeslaslkls 38
                + r l+C  Cg +l   + s
  EEA20013.1 21 NFRLLICESCGFALGPNQAS 40
                56789*****9998766554 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 1.9e-05
  zf-C2H2_12  21 rglvCmvCgeslaslklstikrHIrqvHPeslsls 55 
                 +gl C  C+ + ++++l+++ +H r++HP+  + s
  EEA20013.1  89 NGLACRLCE-TYYTINLDNLLKHLRHQHPDRPRSS 122
                 79******7.579****************976655 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0      0.49   2.9e+03      19      43 ..      27      47 ..      25      48 .. 0.60
   2 ?   13.5   0.9   9.3e-06     0.056      17      44 .]      91     116 ..      80     116 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.49
                ETTTTEE----SSTHHHHHHHHHS- CS
      zf-BED 19 CryCgkilsrgggttnLkrHLrrkH 43
                C  Cg+ l    g +  ++H + kH
  EEA20013.1 27 CESCGFAL----GPNQASSHFWEKH 47
                66677665....4556666666666 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 9.3e-06
                 -EETTTTEE----SSTHHHHHHHHHS-H CS
      zf-BED  17 avCryCgkilsrgggttnLkrHLrrkHp 44 
                   Cr C+  ++   +  nL +HLr++Hp
  EEA20013.1  91 LACRLCETYYTI--NLDNLLKHLRHQHP 116
                 57**********..8************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (786 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       679  (0.0378716); expected 358.6 (0.02)
Passed bias filter:                      531  (0.0296168); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.68u 0.34s 00:00:01.02 Elapsed: 00:00:00.47
# Mc/sec: 4979.05
//
Query:       EEA20014.1  [L=404]
Description: hypothetical protein PMAA_007790 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.024   12.8  20.3      0.033   12.3  20.3    1.1  1  AF-4      AF-4 proto-oncoprotein
        0.1   10.9   1.7       0.12   10.6   1.7    1.1  1  CDC45     CDC45-like protein
       0.17   11.3   4.2       0.21   11.0   4.2    1.1  1  SDA1      SDA1
        3.1    7.5   5.0        4.5    6.9   5.0    1.3  1  CCDC106   Coiled-coil domain-containing protein 106
        4.6    5.3   6.5        5.8    5.0   6.5    1.1  1  Nop14     Nop14-like family


Domain annotation for each model (and alignments):
>> AF-4  AF-4 proto-oncoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3  20.3   9.1e-06     0.033     451     613 ..      58     217 ..      34     238 .. 0.50

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 9.1e-06
        AF-4 451 pssapqstpesvesahsssaeSeSsSeSeSSSeSDSesEs.sssdseanepprtatpepeppatnkWqLdnwlnkvnqlassqeessaessseteeses 548
                 +++++ +++e++ sa  s ++S S S S+S S+S S+s s s sds+   ++ +   +p + ++ +   d      + +as + + ++ s+s+++++ +
  EEA20014.1  58 HARQN-NRQEASDSASDSASDSASDSASDSASDSASDSASdSASDSASDSASDPGR-DPGSDSASDPGRDPARDPARDPASDPAS-HSASHSAIHDRPN 153
                 33322.22333445555555555555555544444443332334444333333322.4555555555555555544566666655.5577777776666 PP

        AF-4 549 pkkeskeqsqgkskssssevvees.seskpkakskaeqkkseekqdkrskqkspaqkeseepntrk 613
                  +++++  +++ ++++s++++ ++ s+   k+  ++++ ++ +k  +r +   p++   + p +r+
  EEA20014.1 154 GCPNNRPRTSHFTSPNSHHIAIPTpSPGPRKRAISHHSIPPMAK--RRAHPIFPSTAYYQGPMQRQ 217
                 66777777777777776666655413333344444444444444..33333344444444444444 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   1.7   3.4e-05      0.12     117     185 ..      49     120 ..      27     212 .. 0.53

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 3.4e-05
       CDC45 117 eeereayealeeeeesdeede.eeeeeddddeeeeeeeeedeedeeedeeeskkkrksksdeeee......sdddd 185
                 +e+ ea++   ++++ +e ++  +++ +d+ +++ +++ +d+ +++++++ s++ + s s    +      sd+++
  EEA20014.1  49 CEDGEAICDHARQNNRQEASDsASDSASDSASDSASDSASDSASDSASDSASDSASDSAS----DpgrdpgSDSAS 120
                 333344444444444432211122222222222222222221111111111111111222....122223322222 PP

>> SDA1  SDA1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   4.2   5.8e-05      0.21      81     151 ..      61     118 ..      41     200 .. 0.50

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 5.8e-05
        SDA1  81 eeekkekreeeeedsddeddeedwevesdddseedseggwidvesdeeeieesdesedeeeeeeeeeekee 151
                 +++++e++    ++ +  d+ +d+  +s++ds++d        +sd+++ + sd+ +d++++  ++ ++++
  EEA20014.1  61 QNNRQEAS----DSAS--DSASDSASDSASDSASD-------SASDSASDSASDSASDSASDPGRDPGSDS 118
                 11111111....1111..11111111111111111.......12222211112211122111111112221 PP

>> CCDC106  Coiled-coil domain-containing protein 106
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   5.0    0.0012       4.5      56     100 ..      56     100 ..      36     159 .. 0.66

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0012
     CCDC106  56 skskksekkaeksesessssseesddsssdssessessegsstek 100
                 + + ++++++e s+s+s s+s+++ ds+sds   s+s+++s ++ 
  EEA20014.1  56 CDHARQNNRQEASDSASDSASDSASDSASDSASDSASDSASDSAS 100
                 444444444555555555555544444444443333333333222 PP

>> Nop14  Nop14-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   6.5    0.0016       5.8     325     398 ..      46     109 ..      29     171 .. 0.41

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0016
       Nop14 325 leeeeeeeefglgkglkataeeeeeededdfeedddlveseseeeeeeeeedeeeeedeeeeeeeeededdlsd 398
                 +++ e+ e++   ++ +   +++ +e +d+ ++++++++s+s +++      +++++d+ +++ +++ +d++sd
  EEA20014.1  46 RQQCEDGEAIC--DHAR---QNNRQEASDSASDSASDSASDSASDS-----ASDSASDSASDSASDSASDSASD 109
                 44333333222..1111...11111111111111111111111111.....11111111111111111111111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (404 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1104  (0.0615762); expected 358.6 (0.02)
Passed bias filter:                      581  (0.0324056); expected 358.6 (0.02)
Passed Vit filter:                        97  (0.00541023); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.69u 0.31s 00:00:01.00 Elapsed: 00:00:00.47
# Mc/sec: 2593.87
//
Query:       EEA20015.1  [L=156]
Description: hypothetical protein PMAA_038840 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (156 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       505  (0.0281667); expected 358.6 (0.02)
Passed bias filter:                      440  (0.0245412); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.30s 00:00:00.76 Elapsed: 00:00:00.48
# Mc/sec: 986.50
//
Query:       EEA20016.1  [L=235]
Description: hypothetical protein PMAA_038850 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.4e-07   30.8   0.2    1.8e-07   30.4   0.2    1.2  1  DUF3435         Protein of unknown function (DUF3435)
  ------ inclusion threshold ------
       0.11   12.5   0.6       0.24   11.5   0.6    1.6  1  zf-Sec23_Sec24  Sec23/Sec24 zinc finger


Domain annotation for each model (and alignments):
>> DUF3435  Protein of unknown function (DUF3435)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.4   0.2   2.1e-11   1.8e-07     315     382 ..       3      68 ..       1      91 [. 0.86

  Alignments for each domain:
  == domain 1  score: 30.4 bits;  conditional E-value: 2.1e-11
     DUF3435 315 kgtelyeelekakrelrnerqrlrrelkkkireeFkeeqpvidierqlsGkaldeevkedledeqlvp 382
                 +g + y++++ +k+ l+ + ++  r+l k+i+ee++ + pv  i++q+sG++ d++ ++d ++e+   
  EEA20016.1   3 QGEPIYNDYQAVKASLAATIRKKERALLKQIQEEYDMNAPVLAIQQQMSGEQFDDDDDDDDDKEG--A 68 
                 6677899*************************************************666666665..3 PP

>> zf-Sec23_Sec24  Sec23/Sec24 zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.6   2.7e-05      0.24      24      36 ..     160     172 ..     154     174 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 2.7e-05
  zf-Sec23_Sec24  24 wiCnfCnhknevp 36 
                     w+C fC  +n++p
      EEA20016.1 160 WQCVFCLASNDLP 172
                     ************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (235 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       716  (0.0399353); expected 358.6 (0.02)
Passed bias filter:                      542  (0.0302304); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 1520.11
//
Query:       EEA20017.1  [L=219]
Description: hypothetical protein PMAA_038860 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.7e-11   43.7   0.0    4.9e-11   42.9   0.0    1.4  1  Acetyltransf_1   Acetyltransferase (GNAT) family
    3.1e-11   43.3   0.0    1.1e-10   41.5   0.0    1.8  2  Acetyltransf_10  Acetyltransferase (GNAT) domain
    1.5e-09   38.1   0.0    3.7e-09   36.9   0.0    1.6  2  Acetyltransf_7   Acetyltransferase (GNAT) domain
    0.00038   20.5   0.0    0.00076   19.6   0.0    1.5  1  Acetyltransf_9   Acetyltransferase (GNAT) domain
    0.00099   19.0   0.0     0.0017   18.2   0.0    1.4  1  FR47             FR47-like protein
     0.0044   17.1   0.0     0.0083   16.2   0.0    1.4  1  Acetyltransf_CG  GCN5-related N-acetyl-transferase


Domain annotation for each model (and alignments):
>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.9   0.0   1.7e-14   4.9e-11      14     117 .]      47     198 ..      30     198 .. 0.80

  Alignments for each domain:
  == domain 1  score: 42.9 bits;  conditional E-value: 1.7e-14
                     HHHHHHHHHH.HHHHHHSTTCEEEEEEETTEEEEEE..................................................EEEEEET.. CS
  Acetyltransf_1  14 ppnedaseee.feesfsleaegllvaeedgeliGfi..................................................sllkipd.. 55 
                     +++  + ++e       + a++  v++ dg+++Gf+                                                  ++++     
      EEA20017.1  47 IQWTVEGLREtL---QTRSAGFRKVCLADGTPVGFAgwsleqtipeksmagvkcisekrtqpikcsedgywhpstldvkswvevskMFRQEKRrv 138
                     334444444422...2234556667889********99999999999999999999999999999999888888888888887776444444488 PP

                     ..TSTTEEEEEEEEESGGGTTSSHHHHHHHHHHHHHHHTTESEEEEEEETTEHHHHHHHHHTTE CS
  Acetyltransf_1  56 ..ekggvayieslaVspeyrgkGlGsaLlealeerareegikkivlaveedndaairlYeklGF 117
                       ++++ + +  + V+p+y+++G+Gs+Ll+   e+a ++g +  +l    +  aai lY+k+GF
      EEA20017.1 139 laNRKNIWRLTMISVNPAYQRQGIGSLLLQWGTEEADRHGWDS-FL---ISSPAAITLYTKFGF 198
                     88888999999********************************.78...68899*********9 PP

>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       0.6   1.8e+03      20      47 ..      52      80 ..      38      89 .. 0.72
   2 !   41.5   0.0   3.8e-14   1.1e-10      50     117 ..     144     209 ..     130     214 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.6
  Acetyltransf_10 20 ealreri.eegealllvaeeggkivGvie 47
                     e lre + + ++ +  v+  +g++vG+++
       EEA20017.1 52 EGLRETLqTRSAGFRKVCLADGTPVGFAG 80
                     66777774467777788999999999985 PP

  == domain 2  score: 41.5 bits;  conditional E-value: 3.8e-14
  Acetyltransf_10  50 dgshisllfVdpeyrgqGigkaLleaveeeaekdgikleltvnaspyavpfYeklGFkavgeeqeenG 117
                      + ++++++ V+p+y++qGig+ Ll+   eea+++g   +  + +sp+a+ +Y k+GF++vge+ + +G
       EEA20017.1 144 NIWRLTMISVNPAYQRQGIGSLLLQWGTEEADRHGW--DSFLISSPAAITLYTKFGFQVVGEVHTSKG 209
                      344999*************************77744..799*********************999988 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       2.6   7.7e+03       8      22 ..      69      83 ..      64      93 .. 0.72
   2 !   36.9   0.0   1.2e-12   3.7e-09      26      75 ..     147     199 ..     124     200 .. 0.73

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 2.6
                    EEETTEEEEEEEEEE CS
  Acetyltransf_7  8 aeddgkivGfialsl 22
                    +  dg +vGf++ sl
      EEA20017.1 69 CLADGTPVGFAGWSL 83
                    445799999987555 PP

  == domain 2  score: 36.9 bits;  conditional E-value: 1.2e-12
                     CTEEEEE-GGGTTSSHHHHHHHH..TT...SEEEEEEEEE.THHHHHHHHHHTTEE CS
  Acetyltransf_7  26 eitrlaVdpeyrgkGiGraLlea..ae...kgiileqlel.naekaikfYeklGFe 75 
                      +t + V+p+y+++GiG+ Ll+   +e   +g   + + l ++++ai +Y k+GF+
      EEA20017.1 147 RLTMISVNPAYQRQGIGSLLLQWgtEEadrHG---WDSFLiSSPAAITLYTKFGFQ 199
                     344499****************7542234445...23455455599*********8 PP

>> Acetyltransf_9  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.0   2.5e-07   0.00076      76     127 ..     148     200 ..     137     201 .. 0.92

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 2.5e-07
                     EEEEEE-CCGTTS-HHHHHHHHHHHHHHHTT.--EEEE--SSHHHHHTTT-EE CS
  Acetyltransf_9  76 vtgVavapehrgrgvlskLlaraleemreeg.qplsllfPssipiYrrfGyei 127
                     +t+++v+p ++++g+ s Ll+   ee++ +g +++ +  P++i++Y +fG+++
      EEA20017.1 148 LTMISVNPAYQRQGIGSLLLQWGTEEADRHGwDSFLISSPAAITLYTKFGFQV 200
                     799*************************99648999999************87 PP

>> FR47  FR47-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0   5.9e-07    0.0017      22      80 ..     146     201 ..     131     206 .. 0.89

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 5.9e-07
                 SSEEEEEE-GGG-SSSHHHHHHHHHHHHHHHS-S-EEEEEETT-HHHHHHHHHHT-EEE CS
        FR47  22 gelgalqvlpehrrrGlgsrlvkalakeiaergktvllvvvasNtpsirlyeklGfeki 80 
                   l ++ v+p  +r+G gs+l +  ++e  + g +++l+  +   ++i ly+k Gf++ 
  EEA20017.1 146 WRLTMISVNPAYQRQGIGSLLLQWGTEEADRHGWDSFLISSP---AAITLYTKFGFQVV 201
                 5799*********************************98665...8**********986 PP

>> Acetyltransf_CG  GCN5-related N-acetyl-transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   2.8e-06    0.0083      21      58 ..     142     179 ..     130     186 .. 0.91

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 2.8e-06
  Acetyltransf_CG  21 kegvldfthTeVpeelrGkGiAkkLvkaalddareegl 58 
                      +++++ +t + V+++++++Gi++ L +   ++a ++g+
       EEA20017.1 142 RKNIWRLTMISVNPAYQRQGIGSLLLQWGTEEADRHGW 179
                      5679999*****************************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (219 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       362  (0.0201908); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.49u 0.31s 00:00:00.80 Elapsed: 00:00:00.49
# Mc/sec: 1332.16
//
Query:       EEA20018.1  [L=219]
Description: hypothetical protein PMAA_038860 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.7e-11   43.7   0.0    4.9e-11   42.9   0.0    1.4  1  Acetyltransf_1   Acetyltransferase (GNAT) family
    3.1e-11   43.3   0.0    1.1e-10   41.5   0.0    1.8  2  Acetyltransf_10  Acetyltransferase (GNAT) domain
    1.5e-09   38.1   0.0    3.7e-09   36.9   0.0    1.6  2  Acetyltransf_7   Acetyltransferase (GNAT) domain
    0.00038   20.5   0.0    0.00076   19.6   0.0    1.5  1  Acetyltransf_9   Acetyltransferase (GNAT) domain
    0.00099   19.0   0.0     0.0017   18.2   0.0    1.4  1  FR47             FR47-like protein
     0.0044   17.1   0.0     0.0083   16.2   0.0    1.4  1  Acetyltransf_CG  GCN5-related N-acetyl-transferase


Domain annotation for each model (and alignments):
>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.9   0.0   1.7e-14   4.9e-11      14     117 .]      47     198 ..      30     198 .. 0.80

  Alignments for each domain:
  == domain 1  score: 42.9 bits;  conditional E-value: 1.7e-14
                     HHHHHHHHHH.HHHHHHSTTCEEEEEEETTEEEEEE..................................................EEEEEET.. CS
  Acetyltransf_1  14 ppnedaseee.feesfsleaegllvaeedgeliGfi..................................................sllkipd.. 55 
                     +++  + ++e       + a++  v++ dg+++Gf+                                                  ++++     
      EEA20018.1  47 IQWTVEGLREtL---QTRSAGFRKVCLADGTPVGFAgwsleqtipeksmagvkcisekrtqpikcsedgywhpstldvkswvevskMFRQEKRrv 138
                     334444444422...2234556667889********99999999999999999999999999999999888888888888887776444444488 PP

                     ..TSTTEEEEEEEEESGGGTTSSHHHHHHHHHHHHHHHTTESEEEEEEETTEHHHHHHHHHTTE CS
  Acetyltransf_1  56 ..ekggvayieslaVspeyrgkGlGsaLlealeerareegikkivlaveedndaairlYeklGF 117
                       ++++ + +  + V+p+y+++G+Gs+Ll+   e+a ++g +  +l    +  aai lY+k+GF
      EEA20018.1 139 laNRKNIWRLTMISVNPAYQRQGIGSLLLQWGTEEADRHGWDS-FL---ISSPAAITLYTKFGF 198
                     88888999999********************************.78...68899*********9 PP

>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       0.6   1.8e+03      20      47 ..      52      80 ..      38      89 .. 0.72
   2 !   41.5   0.0   3.8e-14   1.1e-10      50     117 ..     144     209 ..     130     214 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.6
  Acetyltransf_10 20 ealreri.eegealllvaeeggkivGvie 47
                     e lre + + ++ +  v+  +g++vG+++
       EEA20018.1 52 EGLRETLqTRSAGFRKVCLADGTPVGFAG 80
                     66777774467777788999999999985 PP

  == domain 2  score: 41.5 bits;  conditional E-value: 3.8e-14
  Acetyltransf_10  50 dgshisllfVdpeyrgqGigkaLleaveeeaekdgikleltvnaspyavpfYeklGFkavgeeqeenG 117
                      + ++++++ V+p+y++qGig+ Ll+   eea+++g   +  + +sp+a+ +Y k+GF++vge+ + +G
       EEA20018.1 144 NIWRLTMISVNPAYQRQGIGSLLLQWGTEEADRHGW--DSFLISSPAAITLYTKFGFQVVGEVHTSKG 209
                      344999*************************77744..799*********************999988 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       2.6   7.7e+03       8      22 ..      69      83 ..      64      93 .. 0.72
   2 !   36.9   0.0   1.2e-12   3.7e-09      26      75 ..     147     199 ..     124     200 .. 0.73

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 2.6
                    EEETTEEEEEEEEEE CS
  Acetyltransf_7  8 aeddgkivGfialsl 22
                    +  dg +vGf++ sl
      EEA20018.1 69 CLADGTPVGFAGWSL 83
                    445799999987555 PP

  == domain 2  score: 36.9 bits;  conditional E-value: 1.2e-12
                     CTEEEEE-GGGTTSSHHHHHHHH..TT...SEEEEEEEEE.THHHHHHHHHHTTEE CS
  Acetyltransf_7  26 eitrlaVdpeyrgkGiGraLlea..ae...kgiileqlel.naekaikfYeklGFe 75 
                      +t + V+p+y+++GiG+ Ll+   +e   +g   + + l ++++ai +Y k+GF+
      EEA20018.1 147 RLTMISVNPAYQRQGIGSLLLQWgtEEadrHG---WDSFLiSSPAAITLYTKFGFQ 199
                     344499****************7542234445...23455455599*********8 PP

>> Acetyltransf_9  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.0   2.5e-07   0.00076      76     127 ..     148     200 ..     137     201 .. 0.92

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 2.5e-07
                     EEEEEE-CCGTTS-HHHHHHHHHHHHHHHTT.--EEEE--SSHHHHHTTT-EE CS
  Acetyltransf_9  76 vtgVavapehrgrgvlskLlaraleemreeg.qplsllfPssipiYrrfGyei 127
                     +t+++v+p ++++g+ s Ll+   ee++ +g +++ +  P++i++Y +fG+++
      EEA20018.1 148 LTMISVNPAYQRQGIGSLLLQWGTEEADRHGwDSFLISSPAAITLYTKFGFQV 200
                     799*************************99648999999************87 PP

>> FR47  FR47-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0   5.9e-07    0.0017      22      80 ..     146     201 ..     131     206 .. 0.89

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 5.9e-07
                 SSEEEEEE-GGG-SSSHHHHHHHHHHHHHHHS-S-EEEEEETT-HHHHHHHHHHT-EEE CS
        FR47  22 gelgalqvlpehrrrGlgsrlvkalakeiaergktvllvvvasNtpsirlyeklGfeki 80 
                   l ++ v+p  +r+G gs+l +  ++e  + g +++l+  +   ++i ly+k Gf++ 
  EEA20018.1 146 WRLTMISVNPAYQRQGIGSLLLQWGTEEADRHGWDSFLISSP---AAITLYTKFGFQVV 201
                 5799*********************************98665...8**********986 PP

>> Acetyltransf_CG  GCN5-related N-acetyl-transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   2.8e-06    0.0083      21      58 ..     142     179 ..     130     186 .. 0.91

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 2.8e-06
  Acetyltransf_CG  21 kegvldfthTeVpeelrGkGiAkkLvkaalddareegl 58 
                      +++++ +t + V+++++++Gi++ L +   ++a ++g+
       EEA20018.1 142 RKNIWRLTMISVNPAYQRQGIGSLLLQWGTEEADRHGW 179
                      5679999*****************************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (219 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       362  (0.0201908); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 1449.01
//
Query:       EEA20019.1  [L=219]
Description: hypothetical protein PMAA_038860 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.7e-11   43.7   0.0    4.9e-11   42.9   0.0    1.4  1  Acetyltransf_1   Acetyltransferase (GNAT) family
    3.1e-11   43.3   0.0    1.1e-10   41.5   0.0    1.8  2  Acetyltransf_10  Acetyltransferase (GNAT) domain
    1.5e-09   38.1   0.0    3.7e-09   36.9   0.0    1.6  2  Acetyltransf_7   Acetyltransferase (GNAT) domain
    0.00038   20.5   0.0    0.00076   19.6   0.0    1.5  1  Acetyltransf_9   Acetyltransferase (GNAT) domain
    0.00099   19.0   0.0     0.0017   18.2   0.0    1.4  1  FR47             FR47-like protein
     0.0044   17.1   0.0     0.0083   16.2   0.0    1.4  1  Acetyltransf_CG  GCN5-related N-acetyl-transferase


Domain annotation for each model (and alignments):
>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.9   0.0   1.7e-14   4.9e-11      14     117 .]      47     198 ..      30     198 .. 0.80

  Alignments for each domain:
  == domain 1  score: 42.9 bits;  conditional E-value: 1.7e-14
                     HHHHHHHHHH.HHHHHHSTTCEEEEEEETTEEEEEE..................................................EEEEEET.. CS
  Acetyltransf_1  14 ppnedaseee.feesfsleaegllvaeedgeliGfi..................................................sllkipd.. 55 
                     +++  + ++e       + a++  v++ dg+++Gf+                                                  ++++     
      EEA20019.1  47 IQWTVEGLREtL---QTRSAGFRKVCLADGTPVGFAgwsleqtipeksmagvkcisekrtqpikcsedgywhpstldvkswvevskMFRQEKRrv 138
                     334444444422...2234556667889********99999999999999999999999999999999888888888888887776444444488 PP

                     ..TSTTEEEEEEEEESGGGTTSSHHHHHHHHHHHHHHHTTESEEEEEEETTEHHHHHHHHHTTE CS
  Acetyltransf_1  56 ..ekggvayieslaVspeyrgkGlGsaLlealeerareegikkivlaveedndaairlYeklGF 117
                       ++++ + +  + V+p+y+++G+Gs+Ll+   e+a ++g +  +l    +  aai lY+k+GF
      EEA20019.1 139 laNRKNIWRLTMISVNPAYQRQGIGSLLLQWGTEEADRHGWDS-FL---ISSPAAITLYTKFGF 198
                     88888999999********************************.78...68899*********9 PP

>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       0.6   1.8e+03      20      47 ..      52      80 ..      38      89 .. 0.72
   2 !   41.5   0.0   3.8e-14   1.1e-10      50     117 ..     144     209 ..     130     214 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.6
  Acetyltransf_10 20 ealreri.eegealllvaeeggkivGvie 47
                     e lre + + ++ +  v+  +g++vG+++
       EEA20019.1 52 EGLRETLqTRSAGFRKVCLADGTPVGFAG 80
                     66777774467777788999999999985 PP

  == domain 2  score: 41.5 bits;  conditional E-value: 3.8e-14
  Acetyltransf_10  50 dgshisllfVdpeyrgqGigkaLleaveeeaekdgikleltvnaspyavpfYeklGFkavgeeqeenG 117
                      + ++++++ V+p+y++qGig+ Ll+   eea+++g   +  + +sp+a+ +Y k+GF++vge+ + +G
       EEA20019.1 144 NIWRLTMISVNPAYQRQGIGSLLLQWGTEEADRHGW--DSFLISSPAAITLYTKFGFQVVGEVHTSKG 209
                      344999*************************77744..799*********************999988 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       2.6   7.7e+03       8      22 ..      69      83 ..      64      93 .. 0.72
   2 !   36.9   0.0   1.2e-12   3.7e-09      26      75 ..     147     199 ..     124     200 .. 0.73

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 2.6
                    EEETTEEEEEEEEEE CS
  Acetyltransf_7  8 aeddgkivGfialsl 22
                    +  dg +vGf++ sl
      EEA20019.1 69 CLADGTPVGFAGWSL 83
                    445799999987555 PP

  == domain 2  score: 36.9 bits;  conditional E-value: 1.2e-12
                     CTEEEEE-GGGTTSSHHHHHHHH..TT...SEEEEEEEEE.THHHHHHHHHHTTEE CS
  Acetyltransf_7  26 eitrlaVdpeyrgkGiGraLlea..ae...kgiileqlel.naekaikfYeklGFe 75 
                      +t + V+p+y+++GiG+ Ll+   +e   +g   + + l ++++ai +Y k+GF+
      EEA20019.1 147 RLTMISVNPAYQRQGIGSLLLQWgtEEadrHG---WDSFLiSSPAAITLYTKFGFQ 199
                     344499****************7542234445...23455455599*********8 PP

>> Acetyltransf_9  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.0   2.5e-07   0.00076      76     127 ..     148     200 ..     137     201 .. 0.92

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 2.5e-07
                     EEEEEE-CCGTTS-HHHHHHHHHHHHHHHTT.--EEEE--SSHHHHHTTT-EE CS
  Acetyltransf_9  76 vtgVavapehrgrgvlskLlaraleemreeg.qplsllfPssipiYrrfGyei 127
                     +t+++v+p ++++g+ s Ll+   ee++ +g +++ +  P++i++Y +fG+++
      EEA20019.1 148 LTMISVNPAYQRQGIGSLLLQWGTEEADRHGwDSFLISSPAAITLYTKFGFQV 200
                     799*************************99648999999************87 PP

>> FR47  FR47-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0   5.9e-07    0.0017      22      80 ..     146     201 ..     131     206 .. 0.89

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 5.9e-07
                 SSEEEEEE-GGG-SSSHHHHHHHHHHHHHHHS-S-EEEEEETT-HHHHHHHHHHT-EEE CS
        FR47  22 gelgalqvlpehrrrGlgsrlvkalakeiaergktvllvvvasNtpsirlyeklGfeki 80 
                   l ++ v+p  +r+G gs+l +  ++e  + g +++l+  +   ++i ly+k Gf++ 
  EEA20019.1 146 WRLTMISVNPAYQRQGIGSLLLQWGTEEADRHGWDSFLISSP---AAITLYTKFGFQVV 201
                 5799*********************************98665...8**********986 PP

>> Acetyltransf_CG  GCN5-related N-acetyl-transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   2.8e-06    0.0083      21      58 ..     142     179 ..     130     186 .. 0.91

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 2.8e-06
  Acetyltransf_CG  21 kegvldfthTeVpeelrGkGiAkkLvkaalddareegl 58 
                      +++++ +t + V+++++++Gi++ L +   ++a ++g+
       EEA20019.1 142 RKNIWRLTMISVNPAYQRQGIGSLLLQWGTEEADRHGW 179
                      5679999*****************************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (219 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       362  (0.0201908); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1544.15
//
Query:       EEA20020.1  [L=205]
Description: hypothetical protein PMAA_038870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (205 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       420  (0.0234257); expected 358.6 (0.02)
Passed bias filter:                      343  (0.019131); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1441.23
//
Query:       EEA20021.1  [L=330]
Description: hypothetical protein PMAA_038880 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (330 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       894  (0.0498633); expected 358.6 (0.02)
Passed bias filter:                      645  (0.0359752); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.48u 0.24s 00:00:00.72 Elapsed: 00:00:00.39
# Mc/sec: 2558.87
//
Query:       EEA20022.1  [L=478]
Description: mitochondrial chaperone bcs1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.6e-32  111.2   0.1    1.1e-31  110.3   0.1    1.5  1  BCS1_N          BCS1 N terminal
    6.3e-16   59.0   0.0    1.2e-15   58.1   0.0    1.5  1  AAA             ATPase family associated with various cellula
  ------ inclusion threshold ------
      0.058   13.1   0.4       0.32   10.7   0.0    2.3  3  Cytidylate_kin  Cytidylate kinase
      0.077   12.3   0.0       0.13   11.6   0.0    1.3  1  ATPase          KaiC
       0.15   12.4   0.1        2.5    8.5   0.1    2.4  1  AAA_17          AAA domain


Domain annotation for each model (and alignments):
>> BCS1_N  BCS1 N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.3   0.1   3.1e-35   1.1e-31       4     187 .]      57     214 ..      53     214 .. 0.91

  Alignments for each domain:
  == domain 1  score: 110.3 bits;  conditional E-value: 3.1e-35
      BCS1_N   4 llaaarrllselaslirrrflvsveissdDeaydwvlaWlsaqpasrrsrelsvetrtksrssdssaeedededeeedgkkkkplrylPavgtthlfry 102
                 ++ +ar+++++  +li+++f+ +v++   Deay++v+aW+ +qp+ ++  +l+v+++t++  +d        ++      +kkpl+y P+ g +  f+y
  EEA20022.1  57 FAIFARYAYRHTNDLINKYFTYTVHVYYYDEAYEMVIAWIYRQPFAKEVDSLMVRVKTRDVVQD--------QS-----LRKKPLSYSPWDG-SFSFWY 141
                 4557899**************************************************9998522........12.....2378*********.7***** PP

      BCS1_N 103 kgrllavtRereekssdsetgapeetltltclgrsreilkeLleearelalkkqegktviyraaagsggeWrrvasRpkRplstV 187
                 k+++l ++  ++           +e+++++ +g s++i+ +Ll e+re++lk +++k+ +++++   ggeW+ ++ Rp R++stV
  EEA20022.1 142 KNHRLTLHCHKR---------DHHEEISISSIGTSPKIVMDLLGECREQYLKLSQRKVPVFQPE---GGEWKLTGLRPARDISTV 214
                 ********8882.........249**************************************88...*****************9 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.1   0.0   3.4e-19   1.2e-15       2     130 ..     252     377 ..     251     379 .. 0.89

  Alignments for each domain:
  == domain 1  score: 58.1 bits;  conditional E-value: 3.4e-19
                 EEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTS.EEEEEETGGGHHHHH.......TTCCCHHHHHHHHHHHHH CS
         AAA   2 llyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakp.silfiDEidalaksr.......sgseseeeervvnqLlte 92 
                 ll GppGtGK+++++++a   + +++ +++s+l           ++ lf+++     p + ++++++da++ +r       ++++  ++   ++ Ll++
  EEA20022.1 252 LLDGPPGTGKSSFCHSIAGLYELDIYILNLSSLG-------DGGLARLFTQLP----PrCLVLLEDVDAVGLDRkdtgaqqTQKDVAHHGVSLSGLLNV 339
                 899*******************************.......9999999*8863....45***************999885444455556677899**** PP

                 HHHTTTSSSTEEEEEEESSGGGSTHHHHS.TTSSEEEET CS
         AAA  93 ldgvkkkeskvivigatnrpdkldpallr.gRfdrkiei 130
                 +dgv + e+  ++i+ tn++d+ld+al+r gR+d+ i +
  EEA20022.1 340 IDGVGSPEG-RVLIMSTNYIDHLDKALIRpGRVDKTIVF 377
                 ******877.999**********************9976 PP

>> Cytidylate_kin  Cytidylate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0      0.61   2.2e+03     157     183 ..     102     129 ..      97     132 .. 0.75
   2 ?   -2.1   0.0      0.76   2.7e+03     120     130 ..     209     219 ..     204     237 .. 0.72
   3 ?   10.7   0.0     9e-05      0.32       3      20 ..     253     270 ..     252     296 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.61
                     ---HHHHHHHHHHHHHH.HHCTSSS-S- CS
  Cytidylate_kin 157 svsleellaeikeRDkl.DkerevgpLk 183
                     ++++++l+ ++k RD + D++ + +pL 
      EEA20022.1 102 AKEVDSLMVRVKTRDVVqDQSLRKKPLS 129
                     56789999*******7537777777776 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.76
                     SSIIIIISTT- CS
  Cytidylate_kin 120 RDigtvvfpda 130
                     RDi+tv++ d+
      EEA20022.1 209 RDISTVIMDDT 219
                     88999888775 PP

  == domain 3  score: 10.7 bits;  conditional E-value: 9e-05
                     EE-STTSSHHHHHHHHHH CS
  Cytidylate_kin   3 iDGPagsGKssvaralae 20 
                     +DGP g+GKss ++ +a 
      EEA20022.1 253 LDGPPGTGKSSFCHSIAG 270
                     7**************996 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   3.6e-05      0.13       9      37 ..     233     266 ..     216     269 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 3.6e-05
      ATPase   9 Deilk.....gGipegrvvlitGepGtGKtifal 37 
                 De ++     +Gip  r +l+ G pGtGK+ f+ 
  EEA20022.1 233 DEQTQewytaRGIPYTRGYLLDGPPGTGKSSFCH 266
                 55444566669*******************9986 PP

>> AAA_17  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.1    0.0007       2.5       2      26 ..     255     281 ..     255     390 .. 0.53

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.0007
                 E-TTSSHHHHHHHHHHHH..TEEEEEH CS
      AAA_17   2 GgPGsGKgtqceklveky..gfthlsa 26 
                 G+PG GK+  c  ++  y  ++ +l+ 
  EEA20022.1 255 GPPGTGKSSFCHSIAGLYelDIYILNL 281
                 99************9876333333443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (478 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       579  (0.032294); expected 358.6 (0.02)
Passed bias filter:                      500  (0.0278878); expected 358.6 (0.02)
Passed Vit filter:                        70  (0.00390429); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.42
# Mc/sec: 3412.28
//
Query:       EEA20023.1  [L=76]
Description: hypothetical protein PMAA_038900 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.015   14.2   5.5      0.016   14.1   5.5    1.0  1  FemAB            FemAB family
        0.1   12.0  16.5        0.1   12.0  16.5    1.0  1  GBP_C            Guanylate-binding protein, C-terminal domain
       0.19   11.6  27.2        0.2   11.5  27.2    1.0  1  ARGLU            Arginine and glutamate-rich 1
       0.35   10.8  17.4       0.38   10.7  17.4    1.1  1  MRP-S26          Mitochondrial ribosome subunit S26
       0.51    8.8  10.5       0.53    8.7  10.5    1.0  1  Borrelia_P83     Borrelia P83/100 protein
        1.2    9.2  11.9        1.3    9.1  11.9    1.1  1  MAS20            MAS20 protein import receptor
        1.5    8.1  13.8        1.6    8.0  13.8    1.0  1  U79_P34          HSV U79 / HCMV P34
        1.5    9.1  10.1        1.5    9.1  10.1    1.0  1  Vfa1             AAA-ATPase Vps4-associated protein 1
          2    8.1  13.2        2.1    8.1  13.2    1.1  1  DUF4637          Domain of unknown function (DUF4637)
        2.4    7.5   6.2        2.4    7.5   6.2    1.0  1  GNAT_acetyltr_2  GNAT acetyltransferase 2
        2.5    7.6  22.2        2.6    7.6  22.2    1.1  1  DDRGK            DDRGK domain
        5.7    7.0  14.2        6.4    6.8  14.2    1.1  1  UPF0242          Uncharacterised protein family (UPF0242) N-t
          6    6.1  21.9          7    5.8  21.9    1.2  1  Radial_spoke_3   Radial spoke protein 3
        6.8    5.5  11.8          7    5.4  11.8    1.0  1  NARP1            NMDA receptor-regulated protein 1
        7.1    5.2   8.4          7    5.2   8.4    1.0  1  TT_ORF1          TT viral orf 1
        7.8    5.4  11.8        7.5    5.5  11.8    1.0  1  DUF3987          Protein of unknown function (DUF3987)
          8    5.7  11.1          8    5.7  11.1    1.1  1  DUF4407          Domain of unknown function (DUF4407)
        9.3    6.1  17.8        9.8    6.0  17.8    1.1  1  eIF3_subunit     Translation initiation factor eIF3 subunit
        9.3    5.5  10.3        9.8    5.5  10.3    1.0  1  Rtf2             Rtf2 RING-finger


Domain annotation for each model (and alignments):
>> FemAB  FemAB family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   5.5   1.7e-05     0.016     255     324 ..       3      74 ..       1      76 [] 0.87

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 1.7e-05
       FemAB 255 ekklakleekleknpe..kkkkkklkelekqlaslekelkeaeefiekdgeevvlaaalflcfdqevvylys 324
                 +++l++l+++le++ +  ++++++ +e+e+  ++ e++ +eae+++e+++++++l+  ++  f + +++++s
  EEA20023.1   3 QQELDELRKHLEEERRrrEEAERRQEEAERRQEEAERRREEAERQQEEAERNLNLEIQHSPNFSTRATNISS 74 
                 6788888888888877789999999********************999999999999999999998888887 PP

>> GBP_C  Guanylate-binding protein, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0  16.5   0.00011       0.1     195     253 ..       2      60 ..       1      72 [. 0.92

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00011
       GBP_C 195 tdkaltakekeieaeqakaeaaeaekelleekqkeeeqrmeakeksleehvkqLkekle 253
                 ++++l++  k+ e+e+ ++e+ae+ +e+ e +q+e e+r e+ e+++ee  ++L+  ++
  EEA20023.1   2 SQQELDELRKHLEEERRRREEAERRQEEAERRQEEAERRREEAERQQEEAERNLNLEIQ 60 
                 6899*************************************************987665 PP

>> ARGLU  Arginine and glutamate-rich 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5  27.2   0.00022       0.2      63     120 ..       3      60 ..       1      71 [. 0.82

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00022
       ARGLU  63 eaeleeekrkeeeerkkreelerileenkrkveeaqrklaEerlaeleekrrlkeerq 120
                 ++el e ++  eeer++ree er  ee +r+ eea+r+++E + ++ e++r l+ e q
  EEA20023.1   3 QQELDELRKHLEEERRRREEAERRQEEAERRQEEAERRREEAERQQEEAERNLNLEIQ 60 
                 6888999999999999999999999999999999999999888888888887776665 PP

>> MRP-S26  Mitochondrial ribosome subunit S26
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7  17.4    0.0004      0.38      85     142 ..      10      68 ..       3      76 .] 0.78

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.0004
     MRP-S26  85 NaelaelReerlkkeaee.kkeeilerieekeqkeeekkekaeeevlqekeesktFITe 142
                  + l+e+R  r ++e+ + + e+++e++e++++++e ++e+ae++++ e++ s++F T+
  EEA20023.1  10 RKHLEEERRRREEAERRQeEAERRQEEAERRREEAERQQEEAERNLNLEIQHSPNFSTR 68 
                 566777787777777655055667788888888899999*****************997 PP

>> Borrelia_P83  Borrelia P83/100 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7  10.5   0.00056      0.53     221     306 ..      15      53 ..       2      73 .. 0.44

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00056
  Borrelia_P83 221 eldkkqkdadkakkkadtaednadkqrkevreklqeaknlpepadvsskkedkkvaeekkreiekaqkeikkkdeeakkakdakae 306
                   e  ++ ++a++ +++a++++++a+++r+e++++++e                                               +  
    EEA20023.1  15 EERRRREEAERRQEEAERRQEEAERRREEAERQQEE-----------------------------------------------AER 53 
                   223333333333333333333333333333333333...............................................212 PP

>> MAS20  MAS20 protein import receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1  11.9    0.0014       1.3      24      88 ..       8      68 ..       3      76 .] 0.69

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0014
       MAS20 24 efkkklrerrkkqakaakeeeeaekaekkkkealeeakeelptdaeevekfFleevqlGEellaq 88
                e +k+l+e+r+++++a++++eeae++++++    e+ +ee  +++ee e+ +  e+q   + +++
  EEA20023.1  8 ELRKHLEEERRRREEAERRQEEAERRQEEA----ERRREEAERQQEEAERNLNLEIQHSPNFSTR 68
                679999999999997766665555555444....3445557788888888888888877666665 PP

>> U79_P34  HSV U79 / HCMV P34
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0  13.8    0.0017       1.6     152     207 ..      10      62 ..       2      72 .. 0.50

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0017
     U79_P34 152 rkkaddeqrkrsgkqkekrkvedidkkkedekrkeeerkksdedkssdkkeelded 207
                 rk+ ++e+r+r   + e r+ e+ ++++e+ +r++ee  +++e+ + + + e+++ 
  EEA20023.1  10 RKHLEEERRRR--EEAE-RRQEEAERRQEEAERRREEAERQQEEAERNLNLEIQHS 62 
                 44455555555..4444.44455555555444444444444444444444444444 PP

>> Vfa1  AAA-ATPase Vps4-associated protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1  10.1    0.0016       1.5      69     128 ..       3      62 ..       1      75 [. 0.61

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0016
        Vfa1  69 eeeiekvkkeyeekqkkkkekekkkkekdkkdkdkkkekekdkkkekekeeekkkelkka 128
                 ++e+++++k++ee++++++e+e++++e+++++++ +  +e+ + +++e+e++++ e++++
  EEA20023.1   3 QQELDELRKHLEEERRRREEAERRQEEAERRQEEAERRREEAERQQEEAERNLNLEIQHS 62 
                 789999*******99999988887765554444444444433333333344444444443 PP

>> DUF4637  Domain of unknown function (DUF4637)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1  13.2    0.0022       2.1       6      52 ..      10      56 ..       3      74 .. 0.70

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0022
     DUF4637  6 kkeleeleareveeeeaeeeseeedeeedraeeesaaegeeesreae 52
                +k+lee + r +e+e+ +ee e  +ee +r +ee+++++ee++r+++
  EEA20023.1 10 RKHLEEERRRREEAERRQEEAERRQEEAERRREEAERQQEEAERNLN 56
                67777777777777777777777777777777777777777766654 PP

>> GNAT_acetyltr_2  GNAT acetyltransferase 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   6.2    0.0026       2.4     115     167 ..       4      56 ..       1      74 [. 0.68

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0026
  GNAT_acetyltr_2 115 ralellekyyegklssleeeeekeeeeeeekeeeeeklsleeeklkprkelpp 167
                      + l++l+k++e++ ++ ee+e+++ee e+++ee+e++ ++ e++++++++  +
       EEA20023.1   4 QELDELRKHLEEERRRREEAERRQEEAERRQEEAERRREEAERQQEEAERNLN 56 
                      67999*******99999999999888888877666644444444444333333 PP

>> DDRGK  DDRGK domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6  22.2    0.0028       2.6      25      74 ..       4      52 ..       1      67 [. 0.56

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0028
                XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       DDRGK 25 eeereerkkleekreeerkekeekeeekekkkeeeerkkeeekerkeqee 74
                +e  e rk+lee+r ++r+e+e+++ee+e+++ee+er++ee ++++e++e
  EEA20023.1  4 QELDELRKHLEEER-RRREEAERRQEEAERRQEEAERRREEAERQQEEAE 52
                44445555555555.55566666666666655555555555555555444 PP

>> UPF0242  Uncharacterised protein family (UPF0242) N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8  14.2    0.0068       6.4      78     124 ..       7      57 ..       1      72 [. 0.53

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0068
     UPF0242  78 teld...eglktkeealeelqeeeeeLkeeldakeeelerlkeenq.qLqe 124
                  el+   e+ +  +e+ e +qee e+++ee + + ee er +ee + +L+ 
  EEA20023.1   7 DELRkhlEEERRRREEAERRQEEAERRQEEAERRREEAERQQEEAErNLNL 57 
                 222233333345555666666666666666666666666666554433333 PP

>> Radial_spoke_3  Radial spoke protein 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8  21.9    0.0075         7     152     213 ..       3      61 ..       1      76 [] 0.56

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0075
  Radial_spoke_3 152 EeELaalreqqrafeelRnaelaevqrLeeqekrlreekerrlkqqkealkkeketaekiaa 213
                      +EL +lr++ ++  e+R  e ae +r ee+e+r++e + rr + ++++ ++e++++ +i+ 
      EEA20023.1   3 QQELDELRKHLEE--ERRRREEAE-RRQEEAERRQEEAERRREEAERQQEEAERNLNLEIQH 61 
                     5678888777654..344444443.4555666666555555556666666666666666654 PP

>> NARP1  NMDA receptor-regulated protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4  11.8    0.0075         7     406     457 ..       2      51 ..       1      67 [. 0.52

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.0075
                 -HHHHHHHHHHHHHHHHHHHHHHHHHHHHH--.......------------- CS
       NARP1 406 seaerkklrkkakkaekkaekeeaekaekekekkaaekkakkedeeakkede 457
                 s++e   lrk++  +++++e++e +++e+e+++++a  ++++e+ e ++e+ 
  EEA20023.1   2 SQQELDELRKHLEEERRRREEAERRQEEAERRQEEA--ERRREEAERQQEEA 51 
                 666777777776666666655555544444433333..33333333333222 PP

>> TT_ORF1  TT viral orf 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   8.4    0.0075         7      19      52 ..      17      48 ..       4      72 .. 0.42

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.0075
     TT_ORF1 19 rrrrrvrrrrrrrrvRRRrrgrrrrrrrrrrrrr 52
                rrrr+ ++rr+ +  RR +   +rr r    r++
  EEA20023.1 17 RRRREEAERRQEEAERR-QEEAERR-REEAERQQ 48
                22222222222222222.1122222.22222222 PP

>> DUF3987  Protein of unknown function (DUF3987)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5  11.8    0.0079       7.5      67     113 ..       5      53 ..       1      72 [. 0.56

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0079
     DUF3987  67 lreeyeeelkeyeaekkaweaelealekkaakak..eakaeealaelea 113
                 + +e +++l+e +++++++e+++e++e++ ++a+  +++ae++++e+e+
  EEA20023.1   5 ELDELRKHLEEERRRREEAERRQEEAERRQEEAErrREEAERQQEEAER 53 
                 5566666666666666666666666666633333323333333333332 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7  11.1    0.0085         8     189     238 ..       3      51 ..       1      71 [. 0.54

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0085
     DUF4407 189 kaqldaaqaelaelkakldatarlaalraelaeleaerakeraasqaaaa 238
                 +++ld++++ l+e +++++ +a++ + +ae+ + eaer++e+a+ q+++a
  EEA20023.1   3 QQELDELRKHLEEERRRRE-EAERRQEEAERRQEEAERRREEAERQQEEA 51 
                 4566666666666665544.333333333333334444444444444333 PP

>> eIF3_subunit  Translation initiation factor eIF3 subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0  17.8      0.01       9.8      69     115 ..       9      54 ..       2      67 .. 0.78

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.01
  eIF3_subunit  69 kkqkiaekeerrkaeeeeaeeeeeleeedeaarkerlrkaeeesDlk 115
                   + + ++e++ rr++e+e+ +ee+e  +e+ + r+e++++++ee++ +
    EEA20023.1   9 LRKHLEEER-RRREEAERRQEEAERRQEEAERRREEAERQQEEAERN 54 
                   445556655.6777777888899999999999999999999999866 PP

>> Rtf2  Rtf2 RING-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5  10.3      0.01       9.8     171     233 ..       2      64 ..       1      75 [. 0.55

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.01
        Rtf2 171 tkeelellkarleeekakkkkkkkakkkkkakakgskaeaeaaskssseasesskagkkkekk 233
                 +++el++l+++leee+ +++++  ++++ + ++++++ + e+a+++++ea+ + + + +++ +
  EEA20023.1   2 SQQELDELRKHLEEERRRREEAERRQEEAERRQEEAERRREEAERQQEEAERNLNLEIQHSPN 64 
                 6789999*****999888666555555555444444444455445444444333333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (76 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3087  (0.172179); expected 358.6 (0.02)
Passed bias filter:                     1251  (0.0697752); expected 358.6 (0.02)
Passed Vit filter:                       314  (0.0175135); expected 17.9 (0.001)
Passed Fwd filter:                        50  (0.00278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              19  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.43
# Mc/sec: 526.15
//
Query:       EEA20024.1  [L=659]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      2e-06   27.9   1.5    7.5e-06   26.0   0.0    2.5  2  APH             Phosphotransferase enzyme family
    1.7e-05   24.5   0.0    0.00019   21.1   0.0    2.2  2  Choline_kinase  Choline/ethanolamine kinase
     0.0019   17.6   0.1     0.0039   16.6   0.1    1.5  1  Kdo             Lipopolysaccharide kinase (Kdo/WaaP) family
  ------ inclusion threshold ------
      0.012   15.0   0.0      0.024   14.0   0.0    1.4  1  Pkinase         Protein kinase domain
       0.09   12.4   0.0       0.15   11.6   0.0    1.3  1  WaaY            Lipopolysaccharide core biosynthesis protein 


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.6       0.2   7.2e+02     110     143 ..     280     311 ..      92     322 .. 0.62
   2 !   26.0   0.0   2.1e-09   7.5e-06     138     199 ..     560     614 ..     507     617 .. 0.79

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.2
                 -STTTB-SHHCHTCCHHHHHHCHHHCCCGCCTCC CS
         APH 110 paalpladflaqdlellrqlesatarllaselld 143
                  a +  +++ a++ + +rqle +    +  +ll+
  EEA20024.1 280 RALRTSPRDMAWRNWAARQLETW--EMVYDDLLE 311
                 22345556677777788888877..555555555 PP

  == domain 2  score: 26.0 bits;  conditional E-value: 2.1e-09
                 GCCTCCHHHHHHHHHHHHHHHH--SSS-EEEE-SS-SGGGEEEC..TTEEEEE---TT-EEE CS
         APH 138 aselldlleeleeqvlaalaallpgelptvllHgDlhpgNllvdpddgrvtGviDfedaglg 199
                 ++++++  ++l +q +++ ++  +     ++lH D+ pgN+++++d++rv  +iDfe+a++ 
  EEA20024.1 560 QHKFDE--AQLIAQ-AETSLRAIH---NLGVLHSDPIPGNMIWNEDNQRV-MFIDFERARYQ 614
                 333333..444443.444455555...799**************888888.9*******985 PP

>> Choline_kinase  Choline/ethanolamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0      0.09   3.2e+02      29      83 ..      12      66 ..       5     126 .. 0.77
   2 !   21.1   0.0   5.4e-08   0.00019     144     179 ..     581     616 ..     555     618 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.09
                    HHHHTTSSS-EEEEETTEEEEE--TCEE--TTGGGCHHHHHHHHHHHHHHTTCHH CS
  Choline_kinase 29 llserglgpklygifenGrieefiesrtlstedlrepeiskkiAkklaelHslel 83
                     + er++ p l  + ++  i + +++++l+   ++ +++ +++A+ ++el ++  
      EEA20024.1 12 FITERHFTPLLALRESGKEIMKRMHGSELDIGYFQRESVESRVASVIEELYASRQ 66
                    567899999999999999999999********************99999987766 PP

  == domain 2  score: 21.1 bits;  conditional E-value: 5.4e-08
                     -EEEE-S--SGGGEEE.-CTTEEEE--GTT-EEEEH CS
  Choline_kinase 144 pvvfcHnDlqegNillnkeekklvlIDFEYagynyr 179
                     ++   H D ++gN++ n++++++++IDFE a y  r
      EEA20024.1 581 NLGVLHSDPIPGNMIWNEDNQRVMFIDFERARYQKR 616
                     46677************************9999866 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.1   1.1e-06    0.0039     122     174 ..     567     616 ..     541     628 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 1.1e-06
         Kdo 122 allkavgrliaklhragvnHadlyaknillqqeeeeeaeiwliDldkarlrlr 174
                 +l+ +  +  + +h++gv H d  + n+ +++++   +++++iD+++ar + r
  EEA20024.1 567 QLIAQAETSLRAIHNLGVLHSDPIPGNMIWNEDN---QRVMFIDFERARYQKR 616
                 445555567899******************9997...9**********98765 PP

>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   6.7e-06     0.024     101     149 ..     566     615 ..     541     629 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 6.7e-06
                 HHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTE.EEE-SGTTSEESS CS
     Pkinase 101 kkiakqilegleylHskgiiHrDlKpeNiLidekge.lKitDFGlakele 149
                  ++++q  ++l+ +H+ g++H D  p N++ +e+++ ++ +DF  a+  +
  EEA20024.1 566 AQLIAQAETSLRAIHNLGVLHSDPIPGNMIWNEDNQrVMFIDFERARYQK 615
                 456778889999********************66666******9998766 PP

>> WaaY  Lipopolysaccharide core biosynthesis protein (WaaY)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   4.3e-05      0.15     139     186 ..     567     614 ..     537     620 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 4.3e-05
        WaaY 139 evkakikqsieklhqlgmvsgdphrgnfivkkdevriidlsgkrasae 186
                 ++ a+ ++s++++h+lg++  dp  gn+i ++d+ r++ +   ra  +
  EEA20024.1 567 QLIAQAETSLRAIHNLGVLHSDPIPGNMIWNEDNQRVMFIDFERARYQ 614
                 46788999************************9999877666666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (659 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       664  (0.037035); expected 358.6 (0.02)
Passed bias filter:                      480  (0.0267723); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.67u 0.28s 00:00:00.95 Elapsed: 00:00:00.48
# Mc/sec: 4170.00
//
Query:       EEA20025.1  [L=161]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0012   18.8   0.0     0.0013   18.7   0.0    1.2  1  APH       Phosphotransferase enzyme family


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   7.4e-08    0.0013      42     105 ..      61     121 ..      11     142 .. 0.74

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 7.4e-08
                 HHHHHHHHTT-B--B-CTTBS-EEETTEEEEEEE----EE-SS...HHHHHHHHHHHHHHHHHHCCH CS
         APH  42 allrlLakagvpvPevlagdtddeeigllfalieyvpgrsllr...klsaaqlpellealgeflaal 105
                   +++++++ ++vP+v+ +   ++e+g+ f+++ yvpg+ l++   + + +++p++     + +a+l
  EEA20025.1  61 FAYKNVNQNIIRVPRVYRF--VQDELGRGFLFMDYVPGQKLSDldlTVHTEIIPRI----TDIIAHL 121
                 23466666655*******8..77777777**************5555455555554....4444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (161 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       432  (0.024095); expected 358.6 (0.02)
Passed bias filter:                      389  (0.0216967); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.30s 00:00:00.76 Elapsed: 00:00:00.47
# Mc/sec: 1034.04
//
Query:       EEA20026.1  [L=332]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-08   34.4  19.8    2.4e-08   33.3  19.2    1.9  1  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.3  19.2   1.3e-12   2.4e-08       4     164 ..      42     199 ..      38     286 .. 0.86

  Alignments for each domain:
  == domain 1  score: 33.3 bits;  conditional E-value: 1.3e-12
       MFS_1   4 aaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlgaga 101
                 +++ls+++++ +++a+p  ++++++ ++  +g+  +++ + +  +++++G     f+ + v+ ++ +++++g+ll+   +    +l+v+r+++Glg+++
  EEA20026.1  42 VLILSSIDMN-IATAVP-SIGDHFH-TVVDVGWYSSAFRICQRSFQFVFGKGYKLFSIKTVFSFANAISIAGSLLCGP-ARTSiMLIVVRAVAGLGSAG 136
                 4445555555.588888.9******.******************************9999************777773.66666*************** PP

       MFS_1 102 lfpagaaliadwfpkeergraigllsagfslGailg.pllggllasslgWravfyilaivslla 164
                 l++++ +++++++p +++++ +g++++ +   +++   +  +++a   +   vfyi+a+++++a
  EEA20026.1 137 LLSGCFIILVQLSPLRRQPMFTGVMGGVAKPRYAIRtTPRWSYCA-VSWLAMVFYINAPLGVVA 199
                 *************************99887777554366666666.333556688888888887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (332 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       564  (0.0314574); expected 358.6 (0.02)
Passed bias filter:                      353  (0.0196888); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.47
# Mc/sec: 2116.47
//
Query:       EEA20027.1  [L=775]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (775 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       491  (0.0273858); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.72u 0.37s 00:00:01.08 Elapsed: 00:00:00.56
# Mc/sec: 4154.29
//
Query:       EEA20028.1  [L=568]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.7e-12   44.8   0.7    6.8e-11   42.0   0.0    2.9  3  HTH_Tnp_Tc5     Tc5 transposase DNA-binding domain
    7.7e-08   32.2   0.1    1.7e-07   31.1   0.1    1.6  1  DDE_1           DDE superfamily endonuclease
  ------ inclusion threshold ------
       0.32   10.7   0.0       0.32   10.7   0.0    2.8  3  CheR_N          CheR methyltransferase, all-alpha domain
        3.8    7.5   7.9       0.51   10.3   1.6    2.6  2  Myb_DNA-bind_7  Myb DNA-binding like


Domain annotation for each model (and alignments):
>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.0   0.0   1.5e-14   6.8e-11       3      61 ..      72     128 ..      70     133 .. 0.88
   2 ?   -1.8   0.1      0.76   3.4e+03       6      19 ..     215     228 ..     214     231 .. 0.79
   3 ?   -2.6   0.2       1.3     6e+03      25      37 ..     524     536 ..     510     540 .. 0.68

  Alignments for each domain:
  == domain 1  score: 42.0 bits;  conditional E-value: 1.5e-14
                  HHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT..S CS
  HTH_Tnp_Tc5   3 elEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh..g 61 
                   +E+a++ Wi+ql+  g p+t+++i   A +++ +     +p+ +++ +W++ F+kR+  g
   EEA20028.1  72 AEERAVKAWIEQLDIIGTPPTNRMITGCADAILAR----ANPHRTVGPNWVYGFLKRLpdG 128
                  68*****************************9633....579***************9555 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.76
                  HHHHHHHHHHC-CT CS
  HTH_Tnp_Tc5   6 kaLleWirqlrerg 19 
                  ++L eW+++l ++ 
   EEA20028.1 215 NHLEEWYQHLEKED 228
                  6799****997665 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 1.3
                  HHHHHHHHHHHHH CS
  HTH_Tnp_Tc5  25 elirekAqelasl 37 
                  ++ +e+A ++a++
   EEA20028.1 524 RQAKETASRIAQN 536
                  4558899988854 PP

>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.1   0.1   3.7e-11   1.7e-07      47     171 ..     232     353 ..     212     357 .. 0.79

  Alignments for each domain:
  == domain 1  score: 31.1 bits;  conditional E-value: 3.7e-11
       DDE_1  47 ksnrkawltssifeeWLkvfdkrle..aekrkilLlldssrshetvel.leselqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnr 142
                   ++ +   s+++ eW+++f   ++  a ++  lL +d++++h t el + + +++i + ++P++++++lqPld + +++ K+    ++++++ ++   
  EEA20028.1 232 AFSKAGYSNSELIFEWIHHFAIETKkyAGSSWRLLFMDNFDAHITYELyEFCISKKILVYTFPPNTTHILQPLDGVPFQNYKHFHGVEVNNQARAGGVV 330
                 55666777899999*******999988889999***************999***********************9999999999998888888777666 PP

       DDE_1 143 lskeqkkltlldalkfikkAwn.avsketi 171
                  +k        d+l ++ k ++  ++k+ i
  EEA20028.1 331 FDK-------YDFLFNLPKVREqTFTKKII 353
                 666.......55555555555555555555 PP

>> CheR_N  CheR methyltransferase, all-alpha domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   7.1e-05      0.32      12      52 ..     175     215 ..     174     216 .. 0.87
   2 ?   -3.1   1.7       1.5   6.5e+03      26      35 ..     440     449 ..     440     450 .. 0.85
   3 ?   -5.8   2.2         4   1.8e+04      29      39 ..     513     523 ..     513     524 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 7.1e-05
                 HTT-EE--SSTHHHHHTHHHHHHHTTT-SSSHHHHHHTSHS CS
      CheR_N  12 ertGidlsdyKrallkrRlsrRmralglksfeeYldlLrsd 52 
                 ++tG+   + K+ ++  Rl++++r+l++   e +++lL ++
  EEA20028.1 175 DETGFRVGQGKKETVVTRLANLVRELQVLLHENLFHLLTKN 215
                 78************************987777777777765 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 1.5
                 HHTHHHHHHH CS
      CheR_N  26 lkrRlsrRmr 35 
                 l+rR++r m+
  EEA20028.1 440 LERRVRRIMK 449
                 7999999995 PP

  == domain 3  score: -5.8 bits;  conditional E-value: 4
                 HHHHHHHTTT- CS
      CheR_N  29 RlsrRmralgl 39 
                 R++ R r++++
  EEA20028.1 513 RIEERARKRRI 523
                 88999998876 PP

>> Myb_DNA-bind_7  Myb DNA-binding like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.5      0.38   1.7e+03      40      69 ..       4      33 ..       1      44 [. 0.70
   2 ?   10.3   1.6   0.00011      0.51      39      70 ..     502     533 ..     497     546 .. 0.83

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.38
  Myb_DNA-bind_7 40 rtrrqlKlKFkkEerknpeliekalkkrke 69
                    +t ++  + +kkEe   ++  ++ ++++++
      EEA20028.1  4 KTPKKDPETYKKEEDAIKNAYQSYIQNKNQ 33
                    555555567899998888888888888876 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00011
  Myb_DNA-bind_7  39 krtrrqlKlKFkkEerknpeliekalkkrkel 70 
                      r  +++K+K++ Eer ++++i++a ++ +++
      EEA20028.1 502 ARRAEEIKKKWRIEERARKRRIRQAKETASRI 533
                     68889*******************97776664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (568 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1222  (0.0681577); expected 358.6 (0.02)
Passed bias filter:                      592  (0.0330191); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.78u 0.32s 00:00:01.10 Elapsed: 00:00:00.56
# Mc/sec: 3039.52
//
Query:       EEA20029.1  [L=356]
Description: acetyl xylan esterase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.5e-19   69.7   1.2      4e-19   69.0   1.2    1.3  1  Esterase_phd  Esterase PHB depolymerase
    5.8e-13   48.5  12.8    5.8e-13   48.5  12.8    2.6  2  CBM_1         Fungal cellulose binding domain
    2.4e-08   33.7   1.6    3.8e-08   33.1   1.2    1.5  2  Peptidase_S9  Prolyl oligopeptidase family
     0.0011   18.0   0.8     0.0018   17.2   0.2    1.6  2  COesterase    Carboxylesterase family
  ------ inclusion threshold ------
      0.051   13.6   6.4       0.11   12.5   6.4    1.6  1  DUF3439       Domain of unknown function (DUF3439)


Domain annotation for each model (and alignments):
>> Esterase_phd  Esterase PHB depolymerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.0   1.2   1.1e-22     4e-19       5     200 ..      38     240 ..      34     249 .. 0.80

  Alignments for each domain:
  == domain 1  score: 69.0 bits;  conditional E-value: 1.1e-22
  Esterase_phd   5 lylppGarrgamplvvmlhGctqsveefaaGtrmnlladklGvvvlypeqslranaqkcwnwyk..dtdraGrGeaavvvalvdalvdehrvdaarv 99 
                   +y+p         ++v +h c  s+ ++         ad++G++++yp  ++     +c++ y      ++G  ++  +v +v+ +++ ++ d++++
    EEA20029.1  38 IYVPSTLAS-KPAVIVAMHPCGGSATQYYGMYDYHSPADQYGYILIYPSATRD---YNCFDAYSsaSLTHNGGSDSLSIVNMVKYVISTYGADPSKI 130
                   677775443.33467899***********999****************98865...5688888844456778889999******************* PP

  Esterase_phd 100 yvaGlsaGaaladllalhypdvfaavalhsGlalGe.....aadvisaldvmrrGlrqapaaavdalveagaypg....lpal.vvqGdadtvvavk 186
                   y++G s+Ga ++++la  ypdvfaa ++ sG+++ +     aad   + ++  +G  q  +    a v+   ypg     p l v +G ad+v++  
    EEA20029.1 131 YMTGSSSGAIMTNVLAGAYPDVFAAGSVFSGMPYAClygagAADPRMSNQTCSQGQIQHTGQQWAAFVHN-GYPGytgqYPRLqVWHGTADNVISYA 226
                   **********************************994443344444555667788889999999999988.5666222346665889****999887 PP

  Esterase_phd 187 naeslvvalrrlsG 200
                   +  + v +  +  G
    EEA20029.1 227 DLGEEVSQWSTVMG 240
                   77776666666655 PP

>> CBM_1  Fungal cellulose binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.2         1   3.6e+03       5       9 ..      57      61 ..      56      67 .. 0.75
   2 !   48.5  12.8   1.6e-16   5.8e-13       1      29 []     324     352 ..     324     352 .. 0.98

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1
       CBM_1  5 CGGig 9 
                CGG++
  EEA20029.1 57 CGGSA 61
                9*975 PP

  == domain 2  score: 48.5 bits;  conditional E-value: 1.6e-16
       CBM_1   1 lwgQCGGigWtGpTtCvsgatCtyqNeyY 29 
                 +w+QCGGig+tG+TtC+s++tC+++N+yY
  EEA20029.1 324 HWAQCGGIGYTGCTTCASPYTCQKMNDYY 352
                 5**************************** PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.0       2.1   7.5e+03       7      26 ..      41      60 ..      39      64 .. 0.84
   2 !   33.1   1.2   1.1e-11   3.8e-08      30     160 ..      94     226 ..      68     231 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 2.1
                  HHHHHCCT-EEEEE--TTSS CS
  Peptidase_S9  7 lqlladrGyvvvvanirGsg 26
                  +++la++  v+v++++ G++
    EEA20029.1 41 PSTLASKPAVIVAMHPCGGS 60
                  67889999999999999986 PP

  == domain 2  score: 33.1 bits;  conditional E-value: 1.1e-11
                   CHHHHTTSGGGGHHHHHHHHHHHHHHHHTTS--GGGEEEEEETHHHHHHHHHHHH-GGG-SEEEEESE---CCCHHCSTTSTHHHCCCC--TTTCHH CS
  Peptidase_S9  30 eafhdagkrklgqnefdDfiaaaealakegyvdserlaitGgSyGGyltgaalnqrpdlFkaavaevpvvdvlrydsdtdllteeymewgnpeenee 126
                   +a+  a   ++g  +   ++++++++++++ +d++++++tG S G  +t+++++  pd+F+a+    ++     y        +++ +++++ + + 
    EEA20029.1  94 DAYSSASLTHNGGSDSLSIVNMVKYVISTYGADPSKIYMTGSSSGAIMTNVLAGAYPDVFAAGSVFSGMPYACLYGAGA--ADPRMSNQTCS-QGQI 187
                   5666666777888888889********************************************9999999999999885..55588887777.5555 PP

                   HHHHHHHH-CGGG--.....---EEEEEEETT-SSS-TH CS
  Peptidase_S9 127 gykelspyspldnvk.....aypplLlihGlaDdrvppa 160
                   ++  ++ ++ ++n       +yp+l + hG+aD+ + +a
    EEA20029.1 188 QHTGQQWAAFVHNGYpgytgQYPRLQVWHGTADNVISYA 226
                   56677777777776688889*************988775 PP

>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.2   5.1e-07    0.0018      88     202 ..      34     145 ..      21     153 .. 0.87
   2 ?   -2.7   0.0      0.54   1.9e+03     459     496 ..     190     231 ..     175     237 .. 0.75

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 5.1e-07
                 -EEEEEEESSSSSTTSSEEEEEEE--.STTTS-BGCGS-THHHHHHHTSEEEEE----HHHHH-B-SSTTSBS-HHHHHHHHHHHHHHHHGGGGTEEEE CS
  COesterase  88 LyLnvytPkekkeakkklPVlVwihG.ggfqtgsaseydgsaLaaegnvivVtinYRlGvlGFlstgdeeapGNvGllDqvlALrWVkenIasFGGdpe 185
                 L + +y+P+++    +k  V+V +h+ gg  t+   +yd ++ a++ + i++  +       F + ++ +++ N G  D    +++Vk  I+++G dp+
  EEA20029.1  34 LQMYIYVPSTL---ASKPAVIVAMHPcGGSATQYYGMYDYHSPADQYGYILIYPSATRDYNCFDAYSSASLTHNGG-SDSLSIVNMVKYVISTYGADPS 128
                 78889999754...44448999999757777777788999999999999999999999999999999999999966.8********************* PP

                 EEEEEEETHHHHHHHHH CS
  COesterase 186 rvtlfGesAGaasvsll 202
                 ++   G+s+Ga + ++l
  EEA20029.1 129 KIYMTGSSSGAIMTNVL 145
                 ************99887 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 0.54
                 HHHHHHHHHHHSSTTS....TTSS----B.TTTBEEEEESSS CS
  COesterase 459 mmtywtnFaktgnPnk....eeeekWpkytkeeekylkinlk 496
                 + + w+ F+ +g P       + + W  + ++  +y +++++
  EEA20029.1 190 TGQQWAAFVHNGYPGYtgqyPRLQVWHGTADNVISYADLGEE 231
                 567899999999998877777777777777776666666655 PP

>> DUF3439  Domain of unknown function (DUF3439)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   6.4     3e-05      0.11      47      71 ..     291     315 ..     253     320 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 3e-05
     DUF3439  47 ttttttttttttmpttttlptttkm 71 
                  t  tttttt tmp+t+t p tt  
  EEA20029.1 291 ITGGTTTTTTKTMPSTSTTPPTTTS 315
                 46779999999***99887766654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (356 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       512  (0.0285571); expected 358.6 (0.02)
Passed bias filter:                      257  (0.0143343); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2458.17
//
Query:       EEA20030.1  [L=241]
Description: transposable element tc3 transposase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.1e-16   60.0   0.0    3.5e-16   59.3   0.0    1.4  1  DDE_3          DDE superfamily endonuclease
    2.3e-08   34.1   2.1    3.1e-08   33.7   1.0    1.8  2  HTH_Tnp_Tc3_2  Transposase
  ------ inclusion threshold ------
      0.094   12.9   0.0       0.16   12.1   0.0    1.5  1  rve            Integrase core domain


Domain annotation for each model (and alignments):
>> DDE_3  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.3   0.0   5.9e-20   3.5e-16      63     135 ..     113     186 ..      66     193 .. 0.76

  Alignments for each domain:
  == domain 1  score: 59.3 bits;  conditional E-value: 5.9e-20
       DDE_3  63 dfaeflerlletalqak...kivlilDnasiHkseslrelveeeadrlellylPpySPelNpiEivwsklkrellk 135
                 ++a++++++  ++l +    + ++  Dna++H+++ +r+l++e   ++e++ +PpySP+lNpiE++w ++k+ +++
  EEA20030.1 113 ITATVIRQTYMNQLPELlenGDIFMQDNAPVHTAHIIRDLLRE--MQVEVMIWPPYSPDLNPIENLWAIMKTIIRQ 186
                 444466666666555445559**********************..***************************9987 PP

>> HTH_Tnp_Tc3_2  Transposase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.7   1.0   5.2e-12   3.1e-08      30      71 ..       3      44 ..       1      45 [. 0.96
   2 ?   -3.3   0.0       1.9   1.2e+04      13      37 ..      96     120 ..      91     121 .. 0.71

  Alignments for each domain:
  == domain 1  score: 33.7 bits;  conditional E-value: 5.2e-12
  HTH_Tnp_Tc3_2 30 vsreTirrrLrkaglkkrkprkkplLskknrkaRLeFAkehl 71
                   +s++Tirr+ ++  ++k+  r +p++ ++n+++RL++A+++ 
     EEA20030.1  3 CSKTTIRRVFHNLYMRKWLQRDRPEILPQNAEKRLQWAQRYA 44
                   8**************************************997 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 1.9
  HTH_Tnp_Tc3_2  13 ritlreLanelkeeGksvsreTirr 37 
                    r++l  L+++ +++G  + ++ ir+
     EEA20030.1  96 RTSLVPLTSDGSSRGGGITATVIRQ 120
                    5777778888877777777777765 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   2.8e-05      0.16      67     107 ..     133     173 ..      67     182 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 2.8e-05
         rve  67 pervlsDngseytskafrefladlgirvsftrpgrpqdnGk 107
                  +++  Dn++  t++ +r++l++++++v   +p++p+ n +
  EEA20030.1 133 GDIFMQDNAPVHTAHIIRDLLREMQVEVMIWPPYSPDLNPI 173
                 688999******************************99974 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (241 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       481  (0.026828); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.47u 0.30s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1584.01
//
Query:       EEA20031.1  [L=967]
Description: 3-hydroxyacyl-CoA dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.6e-25   88.5   0.0      8e-25   87.8   0.0    1.4  1  3HCDH_N         3-hydroxyacyl-CoA dehydrogenase, NAD binding 
    4.5e-22   78.5   0.0    1.2e-21   77.1   0.0    1.8  1  3HCDH           3-hydroxyacyl-CoA dehydrogenase, C-terminal d
    2.6e-05   24.2   7.1    2.6e-05   24.2   7.1    1.8  2  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
    5.7e-05   22.8   0.0     0.0071   16.0   0.0    3.1  3  ApbA            Ketopantoate reductase PanE/ApbA
  ------ inclusion threshold ------
      0.017   14.3   0.0      0.033   13.4   0.0    1.4  1  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
      0.018   15.6   0.0      0.049   14.2   0.0    1.8  1  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
      0.021   14.2   0.0       0.04   13.3   0.0    1.4  1  2-Hacid_dh_C    D-isomer specific 2-hydroxyacid dehydrogenase
      0.091   12.8   0.0       0.45   10.5   0.0    2.2  3  HSDR_N_2        Type I restriction enzyme R protein N terminu
       0.13   12.3   0.0       0.23   11.4   0.0    1.4  1  NAD_Gly3P_dh_N  NAD-dependent glycerol-3-phosphate dehydrogen


Domain annotation for each model (and alignments):
>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.8   0.0     4e-28     8e-25       2     178 ..     692     864 ..     691     866 .. 0.86

  Alignments for each domain:
  == domain 1  score: 87.8 bits;  conditional E-value: 4e-28
                 EEEE--SCCHHHHHHHHHHTT-EEEEE-S-HHHHHHHHHHHHHHHHCCTTTTSS-HHHHCCCHHCEEEES..-HHHHH.C-SEEEE-S-SSHHHHHHHH CS
     3HCDH_N   2 vaviGaGtmGagiaavfasagleVvlvdiseealekalekieksleklvekgklkeeeveaalarisftt..dleeav.dadlviEavvEnlelKrkvf 97 
                 v ++GaGt G+ +a++  s+g +V+l+d++e++l ++ e +++ l++       + + +++   +i++++   l++a  +a l iE+v+En++lKr v+
  EEA20031.1 692 VVILGAGTQGRRLAYMWSSTGKPVHLIDRQEKQLSEGVEYVQQ-LRS-------SPSAISKNWGNITTSSphGLSTALqKAWLAIECVPENIDLKRTVI 782
                 889**************************************97.332.......333445556666655411456666699****************** PP

                 HHHHCCS-TTSEEEE--SSS-HHHHCCCS..SSGGGEEEEEE-SSTTT--EEEEEE-TT--HHHHHHHHHHHHHTT-EEEEEC CS
     3HCDH_N  98 aelekiakpdailasnTSslsiselaeal..krperviglHFfnPpplmkLvEvvrgekTseetvatvvelakkigktpvvvk 178
                  el+++a++++i+asn+Ss  i e+ e l  k p+r++ +H + Pp++ + +E++ ++kT++ +++++   +k+ g  p +vk
  EEA20031.1 783 GELDALAPEQTIIASNSSSYVIGEIIEPLslKCPSRILSAHCYWPPET-PAIEIMGHDKTDPFVLEQMLSQCKEHGFSPYHVK 864
                 **************************9653379************995.99*******************9999998887776 PP

>> 3HCDH  3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.1   0.0   6.2e-25   1.2e-21       1      97 []     869     965 ..     869     965 .. 0.99

  Alignments for each domain:
  == domain 1  score: 77.1 bits;  conditional E-value: 6.2e-25
                 TTTHHHHHHHHHHHHHHHHHTTSS-HHHHHHHHHHHHHHSSCHHHHHHHHHHHHHHHHHHHHHHHTTTHGGHH-HHHHHHHHTT--BGGGTBSSSBC CS
       3HCDH   1 GFvvnRvlapllneavrlveegvaspediDaamrlglGlpmGpfelldlvgldvakkilevlaeelgerayapsplleklveagrlgrktgkgfyky 97 
                 G++ nR+ a++ +e++  ++egva+p++iDa++++ l  p Gp el+dlvgldv+++i +++a+  ++   +p + l k++e+g+lg k+g+gfy+y
  EEA20031.1 869 GYIYNRIWAAIKRETLLTLHEGVATPKEIDAIFKDVLKTPKGPCELMDLVGLDVVLDIERHYADSRKDLPLEPREYLGKMIENGKLGLKNGRGFYNY 965
                 9**********************************************************************************************98 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.2   7.1   1.3e-08   2.6e-05       2      33 ..      22      63 ..      21      68 .. 0.91
   2 ?   -4.0   0.1       8.9   1.8e+04      20      24 ..     212     216 ..     210     219 .. 0.70

  Alignments for each domain:
  == domain 1  score: 24.2 bits;  conditional E-value: 1.3e-08
                S-HHHHHCT---STSSSS...........-HHHHHCTHHHCCC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPa...........CsnCkklnleCtfy 33
                +Cd Crk +v Cda+k+            C++C+ ++ +Ct +
  EEA20031.1 22 SCDACRKSRVACDAMKGRsaltsptwmnsCTRCQNRGRHCT-F 63
                9*************88888899999****************.4 PP

  == domain 2  score: -4.0 bits;  conditional E-value: 8.9
                 -HHHH CS
     Zn_clus  20 CsnCk 24 
                 C++C 
  EEA20031.1 212 CQECD 216
                 77775 PP

>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0      0.58   1.2e+03      27      54 ..     428     454 ..     421     469 .. 0.79
   2 !   16.0   0.0   3.6e-06    0.0071       1      48 [.     692     741 ..     692     797 .. 0.76
   3 ?    2.6   0.0     0.047        94      76     116 ..     863     902 ..     862     911 .. 0.91

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.58
                 E-SCHHHHHHHHHCEEEEETTCEEEEEE CS
        ApbA  27 ilrsrrlealkknGlrltseggeeilrp 54 
                 +++++  ea++ +G+++t+e+ ++i+  
  EEA20031.1 428 VFHEE-TEAWRAQGIHITEERANQIIAS 454
                 66666.899***********96666555 PP

  == domain 2  score: 16.0 bits;  conditional E-value: 3.6e-06
                 EEEES-SHHHHHHHHHHHHHTHCEEEE-SCH.HHHHHHHHCEEEEETT.C CS
        ApbA   1 iailGaGaiGsllaakLakagadvtlilrsr.rlealkknGlrltseg.g 48 
                 ++ilGaG +G+ la++ + +g +v+li+r++ +l + ++   +l+s+   
  EEA20031.1 692 VVILGAGTQGRRLAYMWSSTGKPVHLIDRQEkQLSEGVEYVQQLRSSPsA 741
                 68****************************98887766665555555544 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.047
                 SSGGGHHHHHHHHGGGECTCEEEEEESSSSCHHHHHTTTST CS
        ApbA  76 vKayqteealeeikplldpntvvlllqNGlgheeelrealp 116
                 vKa++  +  ++i ++++++ + l+l++G+ + +e++++++
  EEA20031.1 863 VKATSIGYIYNRIWAAIKRE-TLLTLHEGVATPKEIDAIFK 902
                 89999999999********8.9***************9994 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   1.7e-05     0.033     128     178 ..     669     725 ..     653     736 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 1.7e-05
                  SECHHHHHHCCSS-T......SEEEEES-SHHHHHHHHHHHHHT-EEEEEESSSSSS CS
                  xxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 128 rtldsaealklkllp......krivvvGgGyiGvElAaalaklgkevtlveardrll 178
                  r  ++a  ++  ++       + +v+ G+G  G  lA ++++ gk v+l+++ ++ l
   EEA20031.1 669 RQQAEASFIRNSKMArskflrEAVVILGAGTQGRRLAYMWSSTGKPVHLIDRQEKQL 725
                  44444555555555455555599*****************************99877 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   2.5e-05     0.049       2      35 ..     692     725 ..     691     736 .. 0.91

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 2.5e-05
                 EEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSS CS
   Pyr_redox   2 vvvvGgGyiglElAgalaelgkkVtvversdkll 35 
                 vv++G+G+ g  lA +++  gk V++++r++k l
  EEA20031.1 692 VVILGAGTQGRRLAYMWSSTGKPVHLIDRQEKQL 725
                 8*****************************9987 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0     2e-05      0.04       9      83 ..     656     732 ..     650     743 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 2e-05
                   TTHHHHHHHHHTTCC......HTTCCGSBS-GTTSEEEEES-SHHHHHHHHHHHHTT-EEEEESSSHHHHHCHHHHTCEEC CS
  2-Hacid_dh_C   9 rrlaeadeevregew......ksekallgkelsgktvGiiGlGrIGqavakrlkafgmkviaydrskkkeeeeeelgvelv 83 
                   + l++a+++v++ +        +++++  ++  ++ v i+G+G  G+++a + ++ g  v  +dr++k+ +    +gve+v
    EEA20031.1 656 KLLPQASKSVQTVRQqaeasfIRNSKMARSKFLREAVVILGAGTQGRRLAYMWSSTGKPVHLIDRQEKQLS----EGVEYV 732
                   444444444433322222333677888888999999******************************88544....344444 PP

>> HSDR_N_2  Type I restriction enzyme R protein N terminus (HSDR_N)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       4.6   9.2e+03      17      37 ..     498     518 ..     495     521 .. 0.79
   2 ?   10.5   0.0   0.00023      0.45       4      90 ..     667     754 ..     666     772 .. 0.91
   3 ?   -2.1   0.0       1.9   3.8e+03      48      69 ..     762     783 ..     755     789 .. 0.81

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 4.6
    HSDR_N_2  17 lgypkeliavekelqlgskkk 37 
                 l y   lia e ++q++s k 
  EEA20031.1 498 LTYHDLLIACERRIQFFSHKT 518
                 67999999*******886554 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00023
    HSDR_N_2   4 wvRqklikyLveelgypkeliavekelqlg.skkkraDivvykkdkkpllivecKapsvkiseevleqlksYlealkaeylvvtNgle 90 
                 +vRq+    ++++ + +++++ +e  + lg ++++r  + ++++++kp+ +++  +++++   e ++ql s  +a++ +++ +t ++ 
  EEA20031.1 667 TVRQQAEASFIRNSKMARSKFLREAVVILGaGTQGRRLAYMWSSTGKPVHLIDRQEKQLSEGVEYVQQLRSSPSAISKNWGNITTSSP 754
                 69**************************998899999999999999**********************************99997665 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 1.9
    HSDR_N_2  48 kkpllivecKapsvkiseevle 69 
                 +k++l++ec  +++ ++ +v+ 
  EEA20031.1 762 QKAWLAIECVPENIDLKRTVIG 783
                 5799*********999877665 PP

>> NAD_Gly3P_dh_N  NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00012      0.23       2      37 ..     692     727 ..     691     799 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00012
                     EEEE--SHHHHHHHHHHHTTT--EEEE-S-HHHHHH CS
  NAD_Gly3P_dh_N   2 iavlGaGswGtalAkvlaenghevrlwvreeeliee 37 
                     + +lGaG  G  lA + +++g++v+l+ r+e+++ e
      EEA20031.1 692 VVILGAGTQGRRLAYMWSSTGKPVHLIDRQEKQLSE 727
                     89*****************************66543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (967 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       592  (0.0330191); expected 358.6 (0.02)
Passed bias filter:                      497  (0.0277205); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.72u 0.31s 00:00:01.03 Elapsed: 00:00:00.46
# Mc/sec: 6343.86
//
Query:       EEA20032.1  [L=494]
Description: MFS nicotinic acid transporter Tna1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.8e-37  126.8  31.4    1.1e-36  126.5  31.4    1.1  1  MFS_1          Major Facilitator Superfamily
  ------ inclusion threshold ------
       0.46   10.2   3.5        1.9    8.3   2.2    2.6  2  DUF3188        Protein of unknown function (DUF3188)
        1.8    7.5  25.9        0.2   10.7  12.7    2.3  2  Acyl_transf_3  Acyltransferase family
        2.8    7.7   0.0        2.8    7.7   0.0    3.7  4  FeoB_C         Ferrous iron transport protein B C terminus
        5.4    7.2  12.6       0.06   13.4   1.9    2.9  3  MASE2          MASE2 domain
        8.9    5.0  18.7          1    8.1   4.1    2.7  3  MFS_1_like     MFS_1 like family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  126.5  31.4   3.7e-40   1.1e-36       2     352 ..      47     423 ..      46     424 .. 0.79

  Alignments for each domain:
  == domain 1  score: 126.5 bits;  conditional E-value: 3.7e-40
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgag 100
                 + +++l++l+r+++g a  + + +dl++++++++l lt+++++++++ lp   l  ++ + r+l l ++++++ ++l+ +++++  llv+r++ G++++
  EEA20032.1  47 ATLYLLAFLDRGNIGNAKIEGMLTDLHMTGQQYSLSLTVFFFTYVAFELPSNLLLKKLRPSRLLPLLMFAWGIVMTLMGIVQNYHGLLVCRIFLGVAEA 145
                 67899*************99999***********************************9999************777775466558************* PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg......Wravfyilaivsllafvlfllllpeepperkrkspkeee..... 188
                 +l+p++a++i+ w+p+++     +l+ +++s++ ++  ll+  +a   g      Wr++f++ +++++ + +++ + + + p + k  +++e+e     
  EEA20032.1 146 GLYPGIAYYITLWYPRDRAQYRQALFFSAASVAGAFSGLLAYGIAKMNGvggyagWRWIFILEGLLTVAVSLIAPFAIHDFPETAKFLTEEEREliiti 244
                 ****************999999********************9998888899999*****************9888888888888888887777***** PP

       MFS_1 189 .......kgtgpaplvpawkallkdpvl.....w...illialllfffgfsglltllplylqevlgls.glllaglllallalvgailallagrlsdrl 271
                        +g ++a +++  ++++++ v+     w   + l++  ++++ ++g++++lp++  ++lg++ +  +a ll   +++ +a++a+ a++lsdr 
  EEA20032.1 245 lrnqttgEGFVHADVIQEETKFRARYVIdaltdWqiyLGLFMYWGITCPLYGISFFLPSI-IKDLGYTsS--TAQLLTVPIYITAAVVAIGAAWLSDRR 340
                 **99999888888888844455555555777787744444444444667777*******7.*******52..3333366666666667999*****995 PP

       MFS_1 272 grrrrlllallllllaalglallavt.ssavllllvlvliGfglgfv.fpsllalasdlappeeagtasglfntagslggalg 352
                 + r + ll++ +l+++ +++++++     + +++l+++++ +g   +  + ++ +a++la+  ++++ ++l   +g+ +ga++
  EEA20032.1 341 KQRSPFLLFFMSLIAIGFIVVIASSGrGAPGVVYLGVFIAVVGIYPAfPGNVTWIAVNLAGDYKRAAGMALHIGLGNMAGAMA 423
                 55444444444444444444444444466666666666666655555155555566677799999999999998888888765 PP

>> DUF3188  Protein of unknown function (DUF3188)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0      0.62   1.8e+03      18      48 ..     311     341 ..     304     343 .. 0.69
   2 ?    8.3   2.2   0.00063       1.9       3      42 ..     351     385 ..     351     388 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.62
     DUF3188  18 rqgsdrlqslPallvGlgLivsgavgrgrrr 48 
                 ++++  l  +P+  + +++ +  a +  rr+
  EEA20032.1 311 TSSTAQLLTVPIYITAAVVAIGAAWLSDRRK 341
                 6777788999999997777666665555554 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.00063
     DUF3188   3 plLillgllillysqrqgsdrlqslPallvGlgLivsgav 42 
                 + Li++g+++++ s+  g+ ++ +l     G ++ v+g++
  EEA20032.1 351 MSLIAIGFIVVIASSGRGAPGVVYL-----GVFIAVVGIY 385
                 67***********************.....9999999987 PP

>> Acyl_transf_3  Acyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7  12.7   6.6e-05       0.2     115     264 ..      70     213 ..      32     234 .. 0.71
   2 ?    2.5   5.3     0.021        62     121     198 ..     285     383 ..     255     467 .. 0.52

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 6.6e-05
                    xxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxx....xxxxx RF
  Acyl_transf_3 115 fdetkglmfllfefpatghlWfLwal..fvlylllplllrllrkvrkshlllllilllllslvfir.helfgpatsvgllplpsvla....llffl 203
                                  ++tg+ ++L++   f+ y+++ l  +ll k  ++ +ll l++++  +++++  ++  +    v   +l    +     l+ +
     EEA20032.1  70 T-----------DLHMTGQQYSLSLTvfFFTYVAFELPSNLLLKKLRPSRLLPLLMFAWGIVMTLMgIVQNYHGLLVCRIFL----GvaeaGLYPG 150
                    3...........5678888886665543777777777777777777777776665555544444440444444444444444....34466***** PP

                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxx RF
  Acyl_transf_3 204 fGalladaddrdrnlsrglkislllsllllalillalfgqtdg..gglvasvliqsaslllvs 264
                    + +++  +++rdr + r+ ++  ++s+++++ +lla++  + +  gg+  + +i++   ll +
     EEA20032.1 151 IAYYITLWYPRDRAQYRQALFFSAASVAGAFSGLLAYGIAKMNgvGGYAGWRWIFILEGLLTV 213
                    *****************************************8888777777777766655554 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.021
                    xxxxxxxxxxxxxxxxxxxx...............xxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Acyl_transf_3 121 lmfllfefpatghlWfLwal...............fvlylllpll......lrllrkvrkshlllllilllllslvfirhelfgpatsvgllplps 195
                    +m++++ +p++g + fL+ +               + +y+++++       l   rk+r+++ll++  l+++ + v+i   + g + +v+l  + +
     EEA20032.1 285 FMYWGITCPLYGISFFLPSIikdlgytsstaqlltVPIYITAAVVaigaawLSDRRKQRSPFLLFFMSLIAIGFIVVIASSGRGAPGVVYLGVFIA 380
                    244444444444444444444444444443333332222222222223322333344444444444444444444444444444444444444444 PP

                    xxx RF
  Acyl_transf_3 196 vla 198
                    v +
     EEA20032.1 381 VVG 383
                    433 PP

>> FeoB_C  Ferrous iron transport protein B C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   1.4       2.2   6.6e+03       3      14 ..     113     124 ..     112     127 .. 0.77
   2 ?    7.7   0.0   0.00094       2.8       4      33 ..     322     348 ..     320     349 .. 0.89
   3 ?   -0.7   1.8      0.38   1.1e+03       2      15 ..     351     364 ..     348     366 .. 0.68
   4 ?   -2.5   0.2       1.5   4.3e+03       8      19 ..     444     455 ..     443     460 .. 0.47

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 2.2
      FeoB_C   3 slYllgilvall 14 
                 ++++ gi+++l+
  EEA20032.1 113 LMFAWGIVMTLM 124
                 688999999874 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.00094
      FeoB_C   4 lYllgilvallvalllkkttlkgepspfvm 33 
                 +Y++  +va+ +a+l  +   ++++spf++
  EEA20032.1 322 IYITAAVVAIGAAWLSDR---RKQRSPFLL 348
                 79**************99...577899975 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 0.38
      FeoB_C   2 fslYllgilvallv 15 
                 +sl+++g++v++++
  EEA20032.1 351 MSLIAIGFIVVIAS 364
                 57777777777765 PP

  == domain 4  score: -2.5 bits;  conditional E-value: 1.5
      FeoB_C   8 gilvallvalll 19 
                 g++va ++a l+
  EEA20032.1 444 GFCVAGIIAVLI 455
                 455554444433 PP

>> MASE2  MASE2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   1.9     2e-05      0.06      11      78 ..     116     186 ..     105     190 .. 0.80
   2 ?    0.1   0.5      0.29   8.7e+02      12      43 ..     356     387 ..     347     424 .. 0.68
   3 ?   -3.9   0.1       5.3   1.6e+04      10      22 ..     443     455 ..     440     458 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 2e-05
       MASE2  11 llgaliiaaglleqhfs..lalllllvlnallwPhlayllar.rsrdplrteqrlLliDallgGlwialmg 78 
                 ++g ++ + g++++++   +  ++l v+ a l+P +ay+++    rd  + +q+l +  a ++G++ +l+ 
  EEA20032.1 116 AWGIVMTLMGIVQNYHGllVCRIFLGVAEAGLYPGIAYYITLwYPRDRAQYRQALFFSAASVAGAFSGLLA 186
                 3444455566777777744556789999**************9999********************99985 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.29
       MASE2  12 lgaliiaaglleqhfslalllllvlnallwPh 43 
                 +g+++++a+  ++   +++l + ++ + ++P 
  EEA20032.1 356 IGFIVVIASSGRGAPGVVYLGVFIAVVGIYPA 387
                 56666666666666666666666666667886 PP

  == domain 3  score: -3.9 bits;  conditional E-value: 5.3
       MASE2  10 lllgaliiaagll 22 
                 l+++++ i+a+l+
  EEA20032.1 443 LGFCVAGIIAVLI 455
                 5677888888876 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   3.3    0.0037        11     261     371 ..      78     188 ..      49     194 .. 0.87
   2 ?    8.1   4.1   0.00034         1       8      83 ..     284     362 ..     278     370 .. 0.84
   3 ?   -2.0   0.0      0.41   1.2e+03     356     374 ..     410     427 ..     398     437 .. 0.80

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.0037
  MFS_1_like 261 llGslvalgvvaeiplfffaeklleklGhvklliiallayilrfllyaiienawlvlpievLhgisfgllwaaaveyvskiapksleatgqgllsglyf 359
                   +  +++  +  + + + ++ ll+kl  ++ll + ++a  +   l++i++n   +l+  ++ g++ + l+  ++ y+    p+  +   q+l+ ++  
  EEA20032.1  78 QYSLSLTVFFFTYVAFELPSNLLLKKLRPSRLLPLLMFAWGIVMTLMGIVQNYHGLLVCRIFLGVAEAGLYPGIAYYITLWYPRDRAQYRQALFFSAAS 176
                 555555555566666666678899999999999999*************************************************************** PP

  MFS_1_like 360 glGralGsliGG 371
                  +G ++G l+ G
  EEA20032.1 177 VAGAFSGLLAYG 188
                 *******88766 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.00034
  MFS_1_like   8 yFfffaalgsllP...YltiylkskglkaseigiitlilpltsilsppiwgvlaDrfgkrkkvvilslllsavlflsll 83 
                 +F++++++  l+    +l   +k+ g++ s  +++t+ + +t+ + +   ++l+Dr ++r + +++ + l a+ f++++
  EEA20032.1 284 LFMYWGITCPLYGisfFLPSIIKDLGYTSSTAQLLTVPIYITAAVVAIGAAWLSDRRKQRSPFLLFFMSLIAIGFIVVI 362
                 6777777665543333777788999**************************************************9775 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 0.41
  MFS_1_like 356 glyfglGralGsliGGllw 374
                 +l++glG+  G++++  ++
  EEA20032.1 410 ALHIGLGNMAGAMAS-NFY 427
                 6899********998.444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (494 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       757  (0.0422221); expected 358.6 (0.02)
Passed bias filter:                      428  (0.0238719); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 3275.79
//
Query:       EEA20033.1  [L=847]
Description: endoglucanase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-11   44.6  12.7    3.6e-11   42.8  12.7    2.1  1  CBM_1     Fungal cellulose binding domain
    0.00073   19.2  41.8       0.56   10.4   0.2    9.4  9  BNR       BNR/Asp-box repeat
  ------ inclusion threshold ------
       0.28   11.5  14.4       0.21   11.9   0.6    5.1  4  Kelch_3   Galactose oxidase, central domain
        1.9    8.7  11.3        7.1    7.0   0.1    6.1  8  BNR_6     BNR-Asp box repeat


Domain annotation for each model (and alignments):
>> CBM_1  Fungal cellulose binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.8  12.7   8.1e-15   3.6e-11       2      29 .]     809     836 ..     808     836 .. 0.98

  Alignments for each domain:
  == domain 1  score: 42.8 bits;  conditional E-value: 8.1e-15
       CBM_1   2 wgQCGGigWtGpTtCvsgatCtyqNeyY 29 
                 +gQCGG+ +tGpT+C sg+tCt +N+yY
  EEA20033.1 809 YGQCGGSEYTGPTVCPSGWTCTFYNDYY 836
                 9*************************** PP

>> BNR  BNR/Asp-box repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.8   0.3     0.002       8.8       2      11 ..     123     132 ..     122     133 .. 0.89
   2 !    7.0   1.8    0.0017       7.7       1      11 [.     174     184 ..     174     185 .. 0.89
   3 !    6.2   0.1    0.0032        14       2      10 ..     242     250 ..     241     251 .. 0.87
   4 ?   -3.0   0.1       3.4   1.5e+04       1       7 [.     276     282 ..     276     283 .. 0.87
   5 !    5.9   0.1    0.0038        17       1      12 []     346     357 ..     346     357 .. 0.90
   6 !   10.4   0.2   0.00013      0.56       2      11 ..     518     527 ..     517     528 .. 0.91
   7 !    7.4   0.3    0.0012       5.6       1      12 []     599     610 ..     599     610 .. 0.91
   8 ?   -0.5   1.3       0.5   2.3e+03       1      11 [.     642     652 ..     642     653 .. 0.89
   9 ?   -1.3   0.0      0.92   4.1e+03       3      11 ..     693     701 ..     691     702 .. 0.76

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.002
                 EESSTTSS-E CS
         BNR   2 yStDgGktWs 11 
                  StD G tW+
  EEA20033.1 123 RSTDSGTTWQ 132
                 6********8 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0017
                 EEESSTTSS-E CS
         BNR   1 yyStDgGktWs 11 
                 + StD G tWs
  EEA20033.1 174 WKSTDYGVTWS 184
                 56********8 PP

  == domain 3  score: 6.2 bits;  conditional E-value: 0.0032
                 EESSTTSS- CS
         BNR   2 yStDgGktW 10 
                  S DgG tW
  EEA20033.1 242 KSEDGGVTW 250
                 599****** PP

  == domain 4  score: -3.0 bits;  conditional E-value: 3.4
                 EEESSTT CS
         BNR   1 yyStDgG 7  
                 y+S+ +G
  EEA20033.1 276 YISYSNG 282
                 8999999 PP

  == domain 5  score: 5.9 bits;  conditional E-value: 0.0038
                 EEESSTTSS-EE CS
         BNR   1 yyStDgGktWsk 12 
                 + S D G tWs+
  EEA20033.1 346 WRSLDSGATWSP 357
                 68********95 PP

  == domain 6  score: 10.4 bits;  conditional E-value: 0.00013
                 EESSTTSS-E CS
         BNR   2 yStDgGktWs 11 
                 +StD+G tWs
  EEA20033.1 518 ISTDFGLTWS 527
                 8********9 PP

  == domain 7  score: 7.4 bits;  conditional E-value: 0.0012
                 EEESSTTSS-EE CS
         BNR   1 yyStDgGktWsk 12 
                 y+StDgG +++k
  EEA20033.1 599 YTSTDGGVSFTK 610
                 89*******986 PP

  == domain 8  score: -0.5 bits;  conditional E-value: 0.5
                 EEESSTTSS-E CS
         BNR   1 yyStDgGktWs 11 
                 ++St+ G t++
  EEA20033.1 642 WHSTNSGSTFT 652
                 78*******97 PP

  == domain 9  score: -1.3 bits;  conditional E-value: 0.92
                 ESSTTSS-E CS
         BNR   3 StDgGktWs 11 
                 + D G +W+
  EEA20033.1 693 TEDIGVNWQ 701
                 55679***8 PP

>> Kelch_3  Galactose oxidase, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.0      0.25   1.1e+03      27      40 ..     126     147 ..     121     152 .. 0.79
   2 ?   11.9   0.6   4.7e-05      0.21       2      43 ..     273     315 ..     272     317 .. 0.84
   3 ?    4.3   1.5     0.012        53      11      34 ..     362     383 ..     355     392 .. 0.82
   4 ?   -3.6   0.2       3.5   1.6e+04       9      22 ..     826     836 ..     825     837 .. 0.81

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 0.25
     Kelch_3  27 dtn.tWaei.......aslppa 40 
                 d++ tW+e+       +++p+ 
  EEA20033.1 126 DSGtTWQETvlpfkvgGNMPGR 147
                 4445***998999999999986 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 4.7e-05
     Kelch_3   2 drlyifGGlgddgqdrl.ndvyvydldtntWaeiaslppaRag 43 
                  +lyi+  +g++  d++ ++v+ y+++t+ W+ i+++p+a ++
  EEA20033.1 273 KTLYISYSNGAGPYDGTnGTVHKYNISTGVWTDISPTPMASTN 315
                 579*******6555555899****************9999765 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.012
     Kelch_3  11 gddgqdrlndvyvydldtntWaei 34 
                 +  g ++ln +y yd+++  W ++
  EEA20033.1 362 N--GYPNLNYYYNYDISNAPWLQD 383
                 4..8899**************986 PP

  == domain 4  score: -3.6 bits;  conditional E-value: 3.5
     Kelch_3   9 Glgddgqdrlndvy 22 
                 G++    +++nd+y
  EEA20033.1 826 GWT---CTFYNDYY 836
                 666...899***99 PP

>> BNR_6  BNR-Asp box repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0         3   1.3e+04       3      13 ..     123     133 ..     122     134 .. 0.81
   2 ?    7.0   0.1    0.0016       7.1       1      11 [.     173     183 ..     173     186 .. 0.90
   3 ?   -1.4   0.0      0.83   3.7e+03       2      11 ..     241     250 ..     240     251 .. 0.81
   4 ?    2.6   0.0     0.043   1.9e+02       1      11 [.     345     355 ..     345     358 .. 0.92
   5 ?    0.9   0.0      0.15   6.5e+02       3      11 ..     518     526 ..     518     529 .. 0.87
   6 ?   -2.8   0.1       2.3     1e+04       2      13 ..     599     610 ..     599     611 .. 0.80
   7 ?   -1.4   0.0       0.8   3.6e+03       1      14 []     641     654 ..     641     654 .. 0.89
   8 ?   -2.8   0.0       2.3     1e+04       5      11 ..     723     729 ..     723     730 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 3
       BNR_6   3 rSeDfGknfkq 13 
                 rS D G ++ +
  EEA20033.1 123 RSTDSGTTWQE 133
                 89999999954 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0016
       BNR_6   1 LyrSeDfGknf 11 
                 L++S D+G ++
  EEA20033.1 173 LWKSTDYGVTW 183
                 8********99 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.83
       BNR_6   2 yrSeDfGknf 11 
                 ++SeD G ++
  EEA20033.1 241 FKSEDGGVTW 250
                 89***77777 PP

  == domain 4  score: 2.6 bits;  conditional E-value: 0.043
       BNR_6   1 LyrSeDfGknf 11 
                 ++rS D G+++
  EEA20033.1 345 IWRSLDSGATW 355
                 9*******999 PP

  == domain 5  score: 0.9 bits;  conditional E-value: 0.15
       BNR_6   3 rSeDfGknf 11 
                 +S DfG ++
  EEA20033.1 518 ISTDFGLTW 526
                 699***999 PP

  == domain 6  score: -2.8 bits;  conditional E-value: 2.3
       BNR_6   2 yrSeDfGknfkq 13 
                 y+S D G +f++
  EEA20033.1 599 YTSTDGGVSFTK 610
                 899998988865 PP

  == domain 7  score: -1.4 bits;  conditional E-value: 0.8
       BNR_6   1 LyrSeDfGknfkqi 14 
                 L+ S + G +f+qi
  EEA20033.1 641 LWHSTNSGSTFTQI 654
                 799999999**997 PP

  == domain 8  score: -2.8 bits;  conditional E-value: 2.3
       BNR_6   5 eDfGknf 11 
                 +++G +f
  EEA20033.1 723 SNYGRVF 729
                 69**999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (847 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       861  (0.0480228); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.75u 0.33s 00:00:01.08 Elapsed: 00:00:00.48
# Mc/sec: 5286.28
//
Query:       EEA20034.1  [L=512]
Description: cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-45  156.2   0.0    1.5e-45  155.8   0.0    1.1  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  155.8   0.0   8.6e-50   1.5e-45      86     444 ..     129     492 ..     103     507 .. 0.80

  Alignments for each domain:
  == domain 1  score: 155.8 bits;  conditional E-value: 8.6e-50
                 SSTTCGHHHHHHHHHHHHHHHTSHSTTTHHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHH CS
        p450  86 gvlfangekwkklRrfltptltsfgklsleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelssll 184
                 g +++ +++ k ++++lt++l +       +lv+e+ e l++++ ++++e + +++ + +   ++ + ++i +g+++   +++ l++  ++v  ++ + 
  EEA20034.1 129 GHILDFPAHVKLIHKVLTRELPNL----TDNLVQEIEEGLLKNWGSDTEEWQGVEVWDTVLMLVTRTFNKISVGNPLC-ADQRYLNNTRRYVTSIHAIS 222
                 555555678888888888888877....7899********************************************88.77776544444444443333 PP

                 HCHHHHCCCCCH.HHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHC...SCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHH CS
        p450 185 skssvqllllfp.llkylptkllrklkeavkklkdlldklieerretldsa...kksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTts 279
                 +  +v +   +p +  +l  + +  + +   ++  l++ ++ee + ++++    +++r+ f+  ++++   ++ + +l+ e + a ++++ faG++T+s
  EEA20034.1 223 AVIRVLPSWAKPlIGPILSIPCWFLYWRGKGFAMPLIKSYLEEAQMEINTYgkfSNKRNVFAMWIVQEAIRSQIPRELDPETIYARLMTMNFAGIHTSS 321
                 2223333333332223333444444444444445555555555555555448864455555555555543444449*********************** PP

                 HHHHHHHHHHHHSHHHHHHHHHHHHHHCCTTT.T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS..CEEETTEEE-TT-EEEEEHHHHHT-TT CS
        p450 280 stlswaLyeLaknPevqeklreEidevlgdkr.eptyddlqklpyldavikEtLRlhpvvplllpRevtk..dvvirgylipkGtevivnlyalhrdpe 375
                  t+   L+  + +P+v ++++ E+ ++ ++++ + t   + +l+++d+v++E++Rl+ +++ +l Rev++   + ++g+++pkGt++ + ++ +hrd+e
  EEA20034.1 322 FTTVNLLLDSLSRPNVFSMMKIEVSTTYQQNKcKWTKPAVDNLKFTDNVLRESMRLSGPIV-RLIREVKSenGILLNGVSLPKGTKIATDMHNMHRDEE 419
                 ****************************88776999*************************.999***99778999*********************** PP

                 TSSSTTS--GGGGB-TTS....CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGG CS
        p450 376 vfpnPeeFdpeRFldekg....nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdpp 444
                 +++++++F+p R ++ +g    +    s+ flPFG G++ C+G+ +A +e+kl++at++ ++++++ +++ p+
  EEA20034.1 420 IYKDANTFNPFRLNPFTGrpmpPAVETSENFLPFGHGRHGCPGRYFASHEIKLIIATIIMKYNIKFLDKRPPN 492
                 **********************66699**************************************97654443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (512 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       475  (0.0264934); expected 358.6 (0.02)
Passed bias filter:                      436  (0.0243181); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.46
# Mc/sec: 3344.15
//
Query:       EEA20035.1  [L=533]
Description: maltose permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.5e-69  233.8  23.1    4.1e-69  233.6  23.1    1.0  1  Sugar_tr         Sugar (and other) transporter
    7.8e-21   74.4  35.7      6e-14   51.7  18.8    2.7  3  MFS_1            Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.044   14.0   0.8        0.1   12.8   0.8    1.6  1  Phage_holin_7_1  Mycobacterial 2 TMS Phage Holin (M2 Hol) Fam
       0.13   12.4  16.3       0.14   12.3   1.4    3.4  3  DUF3792          Protein of unknown function (DUF3792)


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  233.6  23.1   9.2e-73   4.1e-69       1     452 []      60     513 ..      60     513 .. 0.92

  Alignments for each domain:
  == domain 1  score: 233.6 bits;  conditional E-value: 9.2e-73
                 HHHHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH.....HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TT CS
    Sugar_tr   1 valvaalggllfgYdtgvigafltllkfaknfglsksksskee..ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaak 97 
                 +a++++++ +++ +d+++ + f+++ +f+k fg+ +  ++      ++ ++ ++ + + Ga+iG ++ag++++r+G++++ + + vl+ + ++++++a+
  EEA20035.1  60 WAFTMCFTIVMESFDMFLNSNFVAQKAFQKTFGVLTDAATGTYaiPTKSQSSLFQAGQCGAFIGVFLAGPITNRIGYRWTTVLGLVLMNATIFISFFAN 158
                 58999****************************988776544468888888889999****************************************** PP

                 TTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HH CS
    Sugar_tr  98 gknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPr 196
                    s+ vl++++v+ G+++Gl+ + +P y+sE+ p  lR+a++   q+++++G+++ ++ ++++nk ++ + wr++l+lq++++  llil+l++PESP+
  EEA20035.1 159 ---SLTVLVISQVFEGVPWGLFIANSPAYASEVVPLPLRSAVTATLQMSWSIGQIIVSVATYATNKRTDYWAWRLPLALQWLFPTPLLILVLLAPESPW 254
                 ...*************************************************************555555***************************** PP

                 HHHHTT-HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH.......HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH..HH CS
    Sugar_tr 197 ylvekgkeeeakevlaklrgeedadrelaeekdsleaeqeee..kaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsks..ll 291
                 +l+ +g+++ea +++++l ++++a ++  ++++ + + +e+     ++  l++  t ++r++i++ + + q++ G n i + ++ +fe++g+s +  + 
  EEA20035.1 255 WLIRRGRKQEALRSIERLGKKPEAAPKSLAMIERTVKIEEQLggAPTLFDLFRG-TDLRRTTIICSMYASQNFAG-NLIANQATFFFEQAGISSDgaFK 351
                 *********************999999999999999984444655555666666.47******************.*********************** PP

                 HHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHH CS
    Sugar_tr 292 vtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalai 390
                  +++ ++++ va  +++fl++ fGRRt++l G+a+   +++ilg  +  +++++   +    ++ +l  ++fa  +gp+ + +++E+++ ++R++ + +
  EEA20035.1 352 LSLVNSCLQLVANACSWFLSSWFGRRTIYLYGTAVNVTLLIILG-LVGSVEQNN-NTNLTQAALGILISFVFAGAMGPISYTIIAETSSVRLRALSTGV 448
                 *******************************************9.444444442.345555666667778899999*********************** PP

                 HHHHHHHHHHHHHHHHHHHHCHHH...T-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 391 avavnwlanflisllfpiiteaig...ggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                   a+  +a + + +l   ++++ g   +g++++v+++ a++  ++ +ff+pe k+r+  e + lf
  EEA20035.1 449 GRAAYYVAEIPMIYLSSKMLNTTGwnlAGKCGYVWGCTAAFCWVMAYFFLPELKHRSYRETDILF 513
                 ***********************99********************************99988765 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.1   0.2    0.0041        19     198     240 ..      43      93 ..       6     106 .. 0.66
   2 !   51.7  18.8   1.3e-17     6e-14       2     257 ..      65     363 ..      64     372 .. 0.68
   3 !   26.9  12.5   4.6e-10   2.1e-06      22     183 ..     337     509 ..     314     527 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.0041
       MFS_1 198 p...awkallkdpvlw.illialllfffgfsglltllpl.......ylqevlgl 240
                     +w+a +++p  w +l++   +f++++ ++ ++l +       + q+++g 
  EEA20035.1  43 HemgVWEAAKSHP--WaCLWAFTMCFTIVMESFDMFLNSnfvaqkaF-QKTFGV 93 
                 0344699******..98788888888888888888888854333333.444444 PP

  == domain 2  score: 51.7 bits;  conditional E-value: 1.3e-17
       MFS_1   2 llaaflsalarsilgpalpl.alaedlg...........ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.l 87 
                 ++++++ ++++++ + ++ + a ++++g           i   +++ l+ +   ga+++++++G++++r+G r++ +lgl+l+ +++++ +f +++  +
  EEA20035.1  65 CFTIVMESFDMFLNSNFVAQkAFQKTFGvltdaatgtyaIPTKSQSSLFQAGQCGAFIGVFLAGPITNRIGYRWTTVLGLVLMNATIFISFF-ANSLtV 162
                 67888999999999999999999999998877777776655555666777888899******************************666668.55555* PP

       MFS_1  88 llvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg...Wrav....fyilaivsllafv..lfllllpeepp 177
                 l+++ v+ G+  g++++++ a++++++p + r+ +++ l++++s+G i+  ++  +         Wr++    +++ +++++l+++     ++l ++ +
  EEA20035.1 163 LVISQVFEGVPWGLFIANSPAYASEVVPLPLRSAVTATLQMSWSIGQIIVSVATYATNKRTDywaWRLPlalqWLFPTPLLILVLLapESPWWLIRRGR 261
                 **************************************************9999999877778788888444433444444444333323344444444 PP

       MFS_1 178 erkrkspkeee.....................kgtgpaplvp...........awkallkdpvlwillialllfffgfsglltllplylqevlgls..g 242
                 + +  +++e++                     +        +             + l++     i+ + +  +f+g+ ++ + +++   e+ g+s  g
  EEA20035.1 262 KQEALRSIERLgkkpeaapkslamiertvkieE--------QlggaptlfdlfRGTDLRRTTI--ICSMYASQNFAGNLIANQATFF--FEQAGISsdG 348
                 444444444435555555555544444443331........0333332112222222333332..2444444445555555555555..6999999887 PP

       MFS_1 243 lllaglllallalvg 257
                 ++ ++l+ + l+lv+
  EEA20035.1 349 AFKLSLVNSCLQLVA 363
                 788777777777776 PP

  == domain 3  score: 26.9 bits;  conditional E-value: 4.6e-10
       MFS_1  22 alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa........sslwlllvlrvlqGlgagalfpagaaliad 112
                 +  e+ gis + +  l  + + +++va+    +ls  fGrr ++l g ++ +  l++l ++        ++l+  +++ +++ ++aga+ p+++++ia+
  EEA20035.1 337 FFFEQAGISSDGAFKLSLVNSCLQLVANACSWFLSSWFGRRTIYLYGTAVNVTLLIILGLVgsveqnnnTNLTQAALGILISFVFAGAMGPISYTIIAE 435
                 4444444444443225555666777777777777777*****************55555634567776555668888888999999************* PP

       MFS_1 113 wfpkeergraigllsagfslGailgpllggllasslgWrav...fyilaivsllafvlfllllpeepperkrks 183
                  ++ + r++ +g+  a++ ++ i    l++ ++   gW ++    y+ +  ++++ v+++++lpe ++++ r++
  EEA20035.1 436 TSSVRLRALSTGVGRAAYYVAEIPMIYLSSKMLNTTGWNLAgkcGYVWGCTAAFCWVMAYFFLPELKHRSYRET 509
                 **********************************************************99**999988887765 PP

>> Phage_holin_7_1  Mycobacterial 2 TMS Phage Holin (M2 Hol) Family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.8   2.2e-05       0.1       3      51 ..     376     426 ..     375     446 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 2.2e-05
  Phage_holin_7_1   3 rktiyllGalvta.llgillisGvlddesaadlidivvav.vsvlvaaala 51 
                      r+tiyl G++v   ll il + G++++++ ++l ++  ++  s + a+a++
       EEA20035.1 376 RRTIYLYGTAVNVtLLIILGLVGSVEQNNNTNLTQAALGIlISFVFAGAMG 426
                      89********98515555556777777777777776666523444555554 PP

>> DUF3792  Protein of unknown function (DUF3792)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   1.4   3.1e-05      0.14      48      90 ..     119     160 ..     105     178 .. 0.86
   2 ?    5.6   3.8    0.0039        18      37     111 ..     352     426 ..     335     429 .. 0.82
   3 ?    0.8   0.1      0.12   5.4e+02      60      81 ..     476     497 ..     461     505 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 3.1e-05
     DUF3792  48 svfigGflagkkakkkgllnGllvGllyflillllsllikksg 90 
                 ++fig flag ++++ g+ +  ++Gl+++  ++++s+++ +s 
  EEA20035.1 119 GAFIGVFLAGPITNRIGYRWTTVLGLVLMNATIFISFFA-NSL 160
                 78*****************************99999998.333 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0039
     DUF3792  37 lsililiililsvfigGflagkkakkkgllnGllvGllyflillllsllikksgsafslkllikllllllagaiG 111
                 ls++++++ +++ ++  fl++   ++  +l+G +v + + +il l++++ +++++ ++ ++l  l+  ++aga+G
  EEA20035.1 352 LSLVNSCLQLVANACSWFLSSWFGRRTIYLYGTAVNVTLLIILGLVGSVEQNNNTNLTQAALGILISFVFAGAMG 426
                 67777778888888888888888899999*************999999997777777888888888888999988 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.12
     DUF3792  60 akkkgllnGllvGllyflilll 81 
                 a+k g+++G+ ++++ ++ +++
  EEA20035.1 476 AGKCGYVWGCTAAFCWVMAYFF 497
                 6788999999999998877554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (533 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       714  (0.0398237); expected 358.6 (0.02)
Passed bias filter:                      385  (0.0214736); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.59u 0.25s 00:00:00.84 Elapsed: 00:00:00.41
# Mc/sec: 3947.68
//
Query:       EEA20036.1  [L=342]
Description: proline-specific permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.8e-41  140.6  20.1    3.2e-34  118.3  17.1    2.8  2  AA_permease    Amino acid permease
    7.8e-09   34.9  19.8    5.4e-08   32.1  14.4    2.4  2  AA_permease_2  Amino acid permease
  ------ inclusion threshold ------
        7.5    7.0   7.7       0.63   10.5   2.2    2.0  2  DUF983         Protein of unknown function (DUF983)


Domain annotation for each model (and alignments):
>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.0   1.5e-08   9.2e-05      50      85 ..       8      43 ..       4      50 .. 0.94
   2 !  118.3  17.1   5.4e-38   3.2e-34     244     421 ..     128     304 ..     104     309 .. 0.95

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 1.5e-08
  AA_permease 50 geiatngpksggfytyasrflgpelGfviGlnylfs 85
                 ge+ + +p  gg  ++a rf+++elGf++G++y+++
   EEA20036.1  8 GEMKSQFPIQGGQFALADRFVSRELGFATGILYWYN 43
                 89********************************97 PP

  == domain 2  score: 118.3 bits;  conditional E-value: 5.4e-38
  AA_permease 244 tifYvlsllligllvprndlgllndsasaaspfvifikesgvsvlaplinaviltaalssansslysasRvlyslakdglaPkvlkkvskrgvPlrai 341
                   ++Yv+s++++gll + +dl+l  +s  a+spfvi+ik++g+++l+++ina+ilt+a+ss+ + l+++sR+ly la +g+aPk++ k  k g P++++
   EEA20036.1 128 NVIYVCSAFMVGLLASPSDLSLNLSSTAAKSPFVIAIKNAGIPALPSIINAAILTSAWSSGCADLFVSSRTLYGLAARGHAPKIFLKTRKDGLPWVSV 225
                  589****************99888788789******************************************************************** PP

  AA_permease 342 llsmiisllalllaslnlaapivfnfllaisaliglivwlliilsylrfRkalkyqgrsieelgfkaallplgvilvlaa 421
                  +++ ++sll++++as   +  +vf ++++++a+ g+i w++i+ ++lr+ k lk++ +  + l+f++ ++p  +  vl++
   EEA20036.1 226 IFCGAFSLLSFMAASKGEE-GTVFGYFSNMTAICGMISWTCILWTSLRWHKGLKVHVHIFNTLSFITTYFPIPFFAVLFF 304
                  ***********99999888.9**************************************************998888886 PP

>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.5   0.1    0.0011       6.5      53      87 ..       9      43 ..       1      49 [. 0.87
   2 !   32.1  14.4   9.1e-12   5.4e-08     239     405 ..     136     305 ..     118     324 .. 0.73

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0011
  AA_permease_2 53 El.ssalprsgGiyvytkaafgkkvaflsawfnwfa 87
                   E+ s  +p  gG++  + ++ ++ ++f +++++w+ 
     EEA20036.1  9 EMkSQ-FPIQGGQFALADRFVSRELGFATGILYWYN 43
                   77677.9***************************96 PP

  == domain 2  score: 32.1 bits;  conditional E-value: 9.1e-12
  AA_permease_2 239 iaflgvvpddei..anlsn.lgsvaalffeavggkvvaiivvilialsllgaintavigssrvlealardgvlPrffakvnkfgspiraiiltaiv 331
                    + +    +++ +  + +s+   s++ +  +++g +++ +i++++i  s++ ++++ ++ ssr+l+ la  g  P+ f k++k g p++++i+   +
     EEA20036.1 136 FMVGLLASPSDLslNLSSTaAKSPFVIAIKNAGIPALPSIINAAILTSAWSSGCADLFVSSRTLYGLAARGHAPKIFLKTRKDGLPWVSVIFCGAF 231
                    43333333333312333333345799999****9************************************************************** PP

  AA_permease_2 332 slillllfllas....saaynfllsvsslgliisyllliigalilrkkrphl....krpgkilvaiigalfllfllvalffp 405
                    sl+ +   ++as    ++ + + +++++++ +is++ ++ + l + k  ++     ++     +++i + f + ++++lff 
     EEA20036.1 232 SLLSF---MAASkgeeGTVFGYFSNMTAICGMISWTCILWTSLRWHKGLKVHvhifNT-----LSFITTYFPIPFFAVLFFA 305
                    *7665...44444679999*****************9998888777777743222233.....3333333333333443333 PP

>> DUF983  Protein of unknown function (DUF983)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.2       1.8   1.1e+04      53      72 ..     121     140 ..     106     144 .. 0.48
   2 ?   10.5   2.2   0.00011      0.63      32      80 ..     255     303 ..     249     308 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 1.8
      DUF983  53 plwvhlliwlpltlllslll 72 
                    v ++ ++ ++ +++++l
  EEA20036.1 121 MASVETANVIYVCSAFMVGL 140
                 33344444444444444444 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00011
      DUF983  32 ilivghlvvplallvevayepplwvhlliwlpltlllsllllrplKGal 80 
                 + i g++  +++l++ ++++  l+vh+ i+ +l ++++ ++++++  ++
  EEA20036.1 255 TAICGMISWTCILWTSLRWHKGLKVHVHIFNTLSFITTYFPIPFFAVLF 303
                 568999*********************************9999876555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       404  (0.0225333); expected 358.6 (0.02)
Passed bias filter:                      240  (0.0133861); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2356.05
//
Query:       EEA20037.1  [L=113]
Description: hypothetical protein PMAA_039040 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-24   85.5   0.4    3.1e-24   85.1   0.4    1.1  1  GCR1_C    Transcriptional activator of glycolytic enzymes
  ------ inclusion threshold ------
      0.041   13.5   0.1      0.078   12.6   0.1    1.5  2  Arnt_C    Aminoarabinose transferase C-terminal domain


Domain annotation for each model (and alignments):
>> GCR1_C  Transcriptional activator of glycolytic enzymes
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.1   0.4   3.4e-28   3.1e-24       1      77 [.       4      79 ..       4      81 .. 0.98

  Alignments for each domain:
  == domain 1  score: 85.1 bits;  conditional E-value: 3.4e-28
      GCR1_C  1 fklsreiktVedlwnEykeglngkpsikslekkygkrWrkdskesklfsrRkkiidfierlieeegitreeavkile 77
                ++lsr+i+tV++lw+E+  gl+g+p ++ +e++yg+rWr dske+ +f rRk+iid+i   +++ gi+ ++a++ +e
  EEA20037.1  4 YQLSRTIQTVRELWTEWAIGLDGQPAVRIIEEQYGARWRADSKERVMFGRRKIIIDEIYARTRD-GISLNKAIEAVE 79
                89**************************************************************.**********99 PP

>> Arnt_C  Aminoarabinose transferase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.1   8.7e-06     0.078      27      73 ..       4      50 ..       1      57 [. 0.85
   2 ?   -2.5   0.0      0.44     4e+03      81      84 ..      94      97 ..      76     112 .. 0.52

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 8.7e-06
                HHHT---EEE.S--GGGHHHHHHSGGGSB-SHHHHHHHHHCS-S-EEE CS
      Arnt_C 27 FYlkrtvilv.eykdelefGlkqepekwiptleaFaarWredkkalal 73
                + l rt++ v e + e ++Gl+ +p   i+  e++ arWr+d+k+ ++
  EEA20037.1  4 YQLSRTIQTVrELWTEWAIGLDGQPAVRII-EEQYGARWRADSKERVM 50
                779*******7789***********99995.589******99877555 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.44
                HHTT CS
      Arnt_C 81 eLka 84
                +L +
  EEA20037.1 94 KLLK 97
                2222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (113 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       405  (0.0225891); expected 358.6 (0.02)
Passed bias filter:                      316  (0.0176251); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.38u 0.28s 00:00:00.66 Elapsed: 00:00:00.41
# Mc/sec: 824.76
//
Query:       EEA20038.1  [L=327]
Description: dihydrodipicolinate synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.8e-33  113.6   0.0      9e-33  113.2   0.0    1.1  1  DHDPS     Dihydrodipicolinate synthetase family


Domain annotation for each model (and alignments):
>> DHDPS  Dihydrodipicolinate synthetase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.2   0.0     5e-37     9e-33       4     288 ..       9     316 ..       7     317 .. 0.78

  Alignments for each domain:
  == domain 1  score: 113.2 bits;  conditional E-value: 5e-37
                 EEEEE----B-TTSSB-HHHHHHHHHHHHHCT-SEEE..ESSCCCTGGGS-HHHHHHHHH...HHHHHHT.TSSEEEEE---SSHHHHHHHHHCCCCCT CS
       DHDPS   4 giitalvtpfdedgkldkealrklieflinkgvdglv..vaGttGEsatlsteekeqlve...iaveaak.gripviagvGsnstseaiklakkaeeaG 96 
                 g+ ++l t fd ++++d  +++   ++l+n  + g+v   aG+ GE+  ls +e+++l++    + ++a+ ++ p++agvG+ st+e iklak a +aG
  EEA20038.1   9 GVYAPLPTFFDDNQEIDYVSYK---NHLLNLATKGMVpvCAGSLGEAVHLSFDERIALIQfirATLDEAGlTSTPIVAGVGGLSTRETIKLAKAASKAG 104
                 6788899999******999998...5777878888752267889***********998761115666666679************************** PP

                 -SEEEEE---SS---....HHHHHHHHHHHHHCHSS-EEEEE-HHHH.SHHHHHHHHHHHHT.STTEEEEEE-SS-C...........THHHHHHCCCS CS
       DHDPS  97 adgvlavtPYYnkps....qeglyqhfkaiieatdlpvilYnvpsrt.gadlspetvkrLae.lenivgvKeavgdl...........eevikikkevg 178
                 ad+ +++ P Y+  s     +++ q++  i e    p++lYn+p+ + g+d+  +++ ++++  +n+ gvK + g             +++ ki ++  
  EEA20038.1 105 ADAGMVILPAYYAASlntdSQQVVQYYVDICEGSPIPLLLYNFPANAgGQDMPSAVISEIINkAPNLCGVKLTCGGSigklvrltaeiQANPKINETRA 203
                 ***999999777554222268999*******9999*********976379*********9998********9876444555666554455555555555 PP

                 TTSEEEES-GGGHHHHHHTT-SEEEESCHHCHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHCCCC......SCCHHHHHHHHCT.TSSSBB.--TT CS
       DHDPS 179 kdlviysGddelllsalslGadGvisvtsniagermrqlikalkeGdlaeaaelnekllplikilfae......pnvilvktalell.GlvveatlrkP 270
                   ++++ G  + l + ++ G++G +s + n+a+  +  l ++l+   l    e  +++ +l +il ++      + ++ +k+al+ l G  v +  rkP
  EEA20038.1 204 FPFLLLDGLIADLTPWMQCGGHGTVSGIPNFAPAASMRLWELLNTKSL--TTEETAECTRLQAILSNAdvaavpGGIRAMKYALNKLhGYGVAP--RKP 298
                 6799****99999****************************9998444..34444455555555544433222344566788886541666666..*** PP

                 S--S-HHHHHHHHHHHHH CS
       DHDPS 271 ltpleeeekeeleallka 288
                 l+pl+e+e ++++++l++
  EEA20038.1 299 LLPLKESEGQAFMDILRE 316
                 *************99975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (327 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       406  (0.0226449); expected 358.6 (0.02)
Passed bias filter:                      387  (0.0215851); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.24s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2386.05
//
Query:       EEA20039.1  [L=214]
Description: hypothetical protein PMAA_039060 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (214 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       246  (0.0137208); expected 358.6 (0.02)
Passed bias filter:                      229  (0.0127726); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.27s 00:00:00.67 Elapsed: 00:00:00.41
# Mc/sec: 1576.16
//
Query:       EEA20040.1  [L=155]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-25   89.8   0.0    1.6e-25   89.5   0.0    1.0  1  DUF3830   Protein of unknown function (DUF3830)


Domain annotation for each model (and alignments):
>> DUF3830  Protein of unknown function (DUF3830)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.5   0.0   8.7e-30   1.6e-25      15     143 ..      20     138 ..       8     140 .. 0.95

  Alignments for each domain:
  == domain 1  score: 89.5 bits;  conditional E-value: 8.7e-30
                 -TTTSHHHHHHHHHH--EEEE-EE-SSSSSEEEEEEE--SSS---S-SEESS--TTEEEEEEEEHHHHSSTTT---EEEE-SSS---EETTTEE--EEE CS
     DUF3830  15 ledkAPetcaavwealplssdviHakyagneiyvllpefaatelpaENaTvtPipGdvvlfsfektelgnpgygyelaifygrgnlllngdvGwvpgnv 113
                 +e +AP+t a ++++lp ++++iH++++g+  +++l e +   +  EN+T++P+ G ++l+         pg + e++ ++ +g+  +++++G +++n+
  EEA20040.1  20 FESDAPKTNALFRSLLPYHQKLIHVRWSGEGLWIPLGETK-FGVSYENHTSHPSAGQILLY---------PGGISETEFLFCYGGVSFASKMGSLAANH 108
                 5788***********************************9.9*******************.........9**************************** PP

                 EEEEEESHHHHHHHHHHHHHH--TT-EEEE CS
     DUF3830 114 fativegldelaeacedilreGakgvtlsl 143
                 f t++eg ++l++ +e +l++Ga++v + +
  EEA20040.1 109 FLTVKEGNENLKALGELVLWKGAQDVVFEV 138
                 *************************98865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (155 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       275  (0.0153383); expected 358.6 (0.02)
Passed bias filter:                      272  (0.015171); expected 358.6 (0.02)
Passed Vit filter:                        10  (0.000557756); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.27s 00:00:00.67 Elapsed: 00:00:00.41
# Mc/sec: 1133.65
//
Query:       EEA20041.1  [L=337]
Description: alpha-ketoglutarate-dependent 2,4-dichlorophenoxyacetate dioxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-47  162.3   0.6    2.4e-47  162.0   0.6    1.1  1  TauD      Taurine catabolism dioxygenase TauD, TfdA family
  ------ inclusion threshold ------
      0.022   14.6   0.0      0.036   13.9   0.0    1.2  1  DPRP      Deoxyribodipyrimidine photo-lyase-related protein


Domain annotation for each model (and alignments):
>> TauD  Taurine catabolism dioxygenase TauD, TfdA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  162.0   0.6   2.7e-51   2.4e-47       8     267 ..      42     316 ..      33     317 .. 0.87

  Alignments for each domain:
  == domain 1  score: 162.0 bits;  conditional E-value: 2.7e-51
        TauD   8 kfgae..gvdlsdleslddelkeelrellaeygvvvfrgfplspeqqlefarrfGplygtpgrgtntkygevld............vssvyesadianl 92 
                 +fgae  gvd++++  + +e++++l +l ++ygv++fr ++l+++ +++f++ +G++   +  +  + + +++             ++ v++++ +++ 
  EEA20041.1  42 AFGAEvsGVDWENP--VPAETVAQLVALQDKYGVLIFRETGLDNARHIAFSQQLGESLEVNPFYYGRENDRLGEpllfdvgnieldRTLVKNESRRWHH 138
                 39***9999***99..77889**********************************4444444444444444444444779999999888888******9 PP

        TauD  93 ayttllwHtDlsylesppgiqlLhcleapatGGe.tpfvDgraaynaLpeelpellegltavrvyyhyrg...gglrteqelpavdkhprtghpvvrth 187
                 +  ++lwHtD+sy+++ +++++L ++ +p +GG  t f+D+r+ay +Lpe+ ++++e l ++++  h+r+        + ++ + + +p++ h +v+t 
  EEA20041.1 139 SLGNALWHTDSSYHQQRSKYSILLSHGNPVKGGSwTHFADTRRAYADLPETKKKEIEDLIVEHDLWHSRKlasPIVYGDPLPHELAAKPPAYHRLVQTA 237
                 99****************************9987699*********************************998444445566677889*********** PP

        TauD 188 pvltgrkallvnppfatrieglgtpeskelldaleelledpeftyrfqwqe.GdlvifdNrrvlHgrtafdeg.eeRhllrc 267
                 p   gr++l+   ++a+ i g + +es++l+ +l +++++p+++++++w   Gd+v +dNr  +H++ ++ e+ + R ++r 
  EEA20041.1 238 P--NGRRTLYLA-AHAKLILGQSFEESQKLIWELIDHCTQPKYVFSMEWLSgGDMVWWDNRQSMHRANPYTEDmAARDVRRS 316
                 *..8********.************************************998******************444466787775 PP

>> DPRP  Deoxyribodipyrimidine photo-lyase-related protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0     4e-06     0.036     133     185 ..     132     186 ..     127     203 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 4e-06
                 HHHHHHC..C-SS--HHHHHHHHHHHHTTTEETTE.EG.GGSS--GGGS------- CS
        DPRP 133 efkewak..grkklrmedFYremRkrlgiLmdedgkPv.GGkWnfDaeNRkklpkk 185
                 e ++w++  g+  ++ ++ Y+++R +++iL+++ + Pv GG W+  a+ R+ + + 
  EEA20041.1 132 ESRRWHHslGNALWHTDSSYHQQRSKYSILLSHGN-PVkGGSWTHFADTRRAYADL 186
                 5566666556677788899************8655.7559****999999887665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (337 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       410  (0.022868); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.39
# Mc/sec: 2569.24
//
Query:       EEA20042.1  [L=1505]
Description: aminohydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.3e-21   76.0   0.0      8e-21   74.7   0.0    1.7  1  Amidohydro_1  Amidohydrolase family
    7.8e-12   45.4   0.0    2.9e-06   27.0   0.0    2.3  2  Amidohydro_3  Amidohydrolase family
      5e-06   26.5   0.1    1.3e-05   25.1   0.1    1.8  1  NACHT         NACHT domain
     0.0028   18.1   0.0     0.0093   16.4   0.0    1.9  1  Goodbye       fungal STAND N-terminal Goodbye domain
  ------ inclusion threshold ------
       0.14   12.6   0.0       0.33   11.4   0.0    1.7  1  RNA_helicase  RNA helicase
       0.15   12.4   0.1       0.33   11.3   0.1    1.5  1  Urease_alpha  Urease alpha-subunit, N-terminal domain


Domain annotation for each model (and alignments):
>> Amidohydro_1  Amidohydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.7   0.0   2.7e-24     8e-21       1     344 []      57     456 ..      57     456 .. 0.70

  Alignments for each domain:
  == domain 1  score: 74.7 bits;  conditional E-value: 2.7e-24
                   EEEE-EEEEEEECETTECSSSGHHHHHSTTHHHHHHHHHHHHHHHHTTEEEEEEEEHSSTHHHHHHHHHHHTS.SSEEEEEEESSEGGS...GCCCS CS
  Amidohydro_1   1 ivlPGlIDaHvHleqsllrgatledwlvppetaaealesgiktalksGtttvadmgattstgiealleaaeel.plglrilggkvsldr...gsaet 93 
                   +v+PG++DaHvHl+   l+g+            a  + sg + a+ +Gttt++++   +  +++ +l+a+ e+    + +  + +sl       +++
    EEA20042.1  57 YVMPGGVDAHVHLSEPQLFGK---------GRPADDFSSGSRSAVAGGTTTIIAFASQDR-SDPSVLNALNEAqQKAQDASYCDYSLHLlisNPTQQ 143
                   69************9999666.........66789**********************655.555555555553011233333333332233322233 PP

                   HHHHHHHHHHHHHHHHHHCTTTCEE.EEEEECGTCCSHHHHHHHHHHHHHHHTTEEEEEETSSCHHHHHHHHHHTTTEEEETTTTSTCC...HHTTT CS
  Amidohydro_1  94 skasreklkagaaetikgkadgvvk.valapheapafsdeelkealkeakkrdlpvaiHaletkgevedaeaafgetiehgthlevaes...lglld 186
                    +          +e+   +++gv +  + + +e  ++ d+++ ++l  a+k  +  +iHa + +    ++ ++  ++     + + a s   +   +
    EEA20042.1 144 AL----------EEFAVLRERGVSSiKIYMTYEVLQLRDNQILDILLQARKDLITTMIHAENGDMLT-WMTEQLERRRLL-APKYHATSrpqILESE 228
                   33..........3344444556666678899*****************************6666665.888888866655.3333333344444444 PP

                   HCCEEEHCTCEEE.HHHHHHHHHHHHHHCEEHHHHHHHH............................................SEHHHHHHHHHHHH CS
  Amidohydro_1 187 eiklilahgvhlt.pteaellkerlkeagvahcpfsnsi............................................lrsgrealrkalde 238
                    ++ ++a   +++ p     l+ +     v++  ++nsi                                             + ++e ++k +++
    EEA20042.1 229 ATNRAIALSQLVEtPI----LIVH-----VSSPLAANSIraaqtsglpvfaetcpqylfltrkgldqpgfegakcvcsppprdGEADLESIWKGIEN 316
                   4444444444444322....2222.....222333333333333333333333455556677788899999999999999999************** PP

                   TSCEEEEEECT..........................TSSCCGGHHHHHHHHHHHHHHCCTTTTHCHCHHHHHHHHHTHHHHHHTT-TTTSSSS-TT CS
  Amidohydro_1 239 GvkvglgtDga..........................asgnslnlleelrlalklqrgllyedeegglslkealrmaTingAkalglddkvGsievG 309
                   G++ +l++D++                            + ++ +  e+rlal l        +++ ls+ ++++++++n+Ak +gl+ ++G++ +G
    EEA20042.1 317 GTFTILSSDHCpfiyddnidgkksaisedaplgrfryIPNGCPGV--ETRLALVL--------SADRLSPQKFVEVTSTNPAKLYGLYPQKGALLPG 403
                   ******************988877766665554444433344433..35555522........3678****************************** PP

                   .SB--EEEECCCT...................CGGGTTTCTSEEEEEEEETTEEE CS
  Amidohydro_1 310 .kdADlvvvdldi...................laafvglkkdgnvkkvivkGklv 344
                     dADl+++   +                   +++++g++ + +++ + v+G++v
    EEA20042.1 404 lSDADLTIWY--PpsslepfpvtnsalhhnvdYTPYEGQTVSQWPRYTLVRGEVV 456
                   889******4..4456777999999***************************997 PP

>> Amidohydro_3  Amidohydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.0   0.0   9.7e-10   2.9e-06       1      29 [.      49      77 ..      49     127 .. 0.77
   2 !   16.1   0.0     2e-06    0.0059     405     472 ..     371     456 ..     341     457 .. 0.92

  Alignments for each domain:
  == domain 1  score: 27.0 bits;  conditional E-value: 9.7e-10
  Amidohydro_3  1 eviDakGrlvlPGFvDsHtHlagggvnlr 29
                  +viDa+G++v+PG+vD+H Hl + ++   
    EEA20042.1 49 RVIDAQGAYVMPGGVDAHVHLSEPQLFGK 77
                  69******************998875554 PP

  == domain 2  score: 16.1 bits;  conditional E-value: 2e-06
  Amidohydro_3 405 deelsleealalyTrgpAkalgledrkGtLevG.adADlvvld....adpldvdppelaear.............vrltvvdGrvv 472
                     +ls ++ +  ++++pAk++gl   kG L +G  dADl+++      +p+ v+ ++l++ +             +r+t+v+G+vv
    EEA20042.1 371 ADRLSPQKFVEVTSTNPAKLYGLYPQKGALLPGlSDADLTIWYppssLEPFPVTNSALHHNVdytpyegqtvsqwPRYTLVRGEVV 456
                   56899999*************************779******99999*************999********************998 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1   0.1   4.5e-09   1.3e-05       2     163 ..     829    1007 ..     828    1010 .. 0.81

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 4.5e-09
                  CEEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-...-HCHHHCCCCTS--SSS-CCHHHHCCSCCCEE.............. CS
       NACHT    2 lvilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgnarsladllfsqlpepaapvsevwavllelperlL.............. 84  
                  +++  G+ GsGK+++ + l++++  + +++      +f++ +++++s ++r++   l +q++e   +v+++    +e++ + L              
  EEA20042.1  829 TLVFFGKLGSGKSVFTANLIEDLLLNIPKG---ATAYFICRHDVTESLQSRTIVGSLIRQWLEFM-NVENILD-AMEQQVQSLanetdldglltvfc 920 
                  67888*******************999887...468888888888888889999********975.5556333.34444444458888999999999 PP

                  .............EEEE-STT-SS-TCH.........HHHHHCTTTTT--EEEEEEECCCHHHHCTTSSCE......EEEE--TCCHHHHHHHHCT CS
       NACHT   85 .............lilDglDelvtdlgqkekqpvrtlLselirkkllpeasllltvrpralrdleeqleea....ivlevegfsesrrkqlvrkyf 163 
                                ++DglD++++     ekq v + L+++ +    ++ +l+lt+r++    l ++l ++    ++ +  +++e++++ ++++ +
  EEA20042.1  921 kflapkwqgkpmfVVIDGLDDCAE----REKQTVIQYLHDWAEN---STLRLFLTTRSELE--LTSLLIDKhfphRSKMQLSLQENDIADYINDEL 1007
                  9999999*****99*********9....5667**********99...8999*******988..666666666666566667889999888887765 PP

>> Goodbye  fungal STAND N-terminal Goodbye domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0   3.1e-06    0.0093      14     119 ..     572     672 ..     554     673 .. 0.85

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 3.1e-06
     Goodbye  14 kdlkdealkelssvedllkqieaekdkfeefrekkeklkealkkilspiqllggiaaqgasmaFgPaslcfnAvsyLikaakkvseiydaieeLfeels 112
                 ++lk ++ +++  + +l+++i+++++     r+   + + ++ ++++ ++ +g++++ g ++    as   +Av + ++ a +++++ ++ ++Lf+e++
  EEA20042.1 572 RNLKSKHHPDAIDIVRLTAEIDRSSQ---LTRKCVGTRFANVLRAIQAFTSIGDVVVGGSQNI--MASGLWAAVRFTLQLATNYTSFLEKFSTLFMEIG 665
                 56666666777777788888888888...667888889999999999999999***9999999..788899**************************** PP

     Goodbye 113 dflerle 119
                  ++ r++
  EEA20042.1 666 RSAPRYQ 672
                 9988875 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00011      0.33       2      36 ..     831     865 ..     830     912 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00011
  RNA_helicase   2 wlyGpsgeGKStlakeLakallkklklkkkdsvys 36 
                   +++G+ g GKS+++ +L+++ll ++ +  +  +++
    EEA20042.1 831 VFFGKLGSGKSVFTANLIEDLLLNIPKGATAYFIC 865
                   799*******************7774444444444 PP

>> Urease_alpha  Urease alpha-subunit, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   0.00011      0.33      64     102 ..       4      42 ..       2      54 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00011
  Urease_alpha  64 ealDlvitnavilDatgivkadigikdgrivaiGkagnp 102
                   +a D+v+ + +++ a+ + + di+ikdg+i+ ++ a   
    EEA20042.1   4 SAFDCVVLDGMVVTAADVGRYDIAIKDGKIALLAPARSL 42 
                   578***************************998877655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1505 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       567  (0.0316247); expected 358.6 (0.02)
Passed bias filter:                      490  (0.02733); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.89u 0.31s 00:00:01.20 Elapsed: 00:00:00.52
# Mc/sec: 8656.63
//
Query:       EEA20043.1  [L=822]
Description: oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.4e-24   86.2   0.1    3.7e-24   85.6   0.1    1.3  1  Peptidase_M20  Peptidase family M20/M25/M40
    8.2e-12   46.0   0.1    1.9e-11   44.9   0.1    1.5  1  GFO_IDH_MocA   Oxidoreductase family, NAD-binding Rossmann fo
    2.4e-05   24.2   0.0    5.1e-05   23.2   0.0    1.5  1  M20_dimer      Peptidase dimerisation domain
  ------ inclusion threshold ------
      0.013   15.2   0.0      0.025   14.3   0.0    1.5  1  Peptidase_M28  Peptidase family M28
      0.015   14.8   0.1      0.036   13.6   0.1    1.6  1  Homez          Homeodomain leucine-zipper encoding, Homez


Domain annotation for each model (and alignments):
>> Peptidase_M20  Peptidase family M20/M25/M40
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.6   0.1     1e-27   3.7e-24       2     206 ..      80     420 ..      79     421 .. 0.92

  Alignments for each domain:
  == domain 1  score: 85.6 bits;  conditional E-value: 1e-27
                    EEEES-BSSTTCGGGSSSTTSEEETTTEEESTTTTTTHHHHHHHHHHHHHHHHHTTT-SSEEEEEEESTTSSTT...........THHHHHHHHHH CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...........xxxxxxxxxxx RF
  Peptidase_M20   2 lgsHlDvVpeeetdgwttpfslteedGklyGrGaddmkggvlaalealralkdegikpkgtivllfqpdEEggr...........gGakallegle 86 
                    +gsHlD++p     g           G+++G        gv+aal++lr +k+ +ik+  +i  + +++EEg+r           +G+++l e   
     EEA20043.1  80 MGSHLDSQP----AG-----------GRFDGI------LGVIAALQVLRVIKEYNIKTYAPIAAIDWTNEEGSRfpkmcsgsgvwSGTEKLSE--- 151
                    68*******....67...........999999......*********************************9889999955555555555555... PP

                    T.........................................TTCESEEEEEEEESSSBTCHSTETEEEE.......................... CS
                    x.........................................xxxxxxxxxxxxxxxxxxxxxxxxxxxx.......................... RF
  Peptidase_M20  87 e.........................................rekvdavfelhieepgileagklaigvv.......................... 115
                                                                ++ a felhie++++le+ ++++gvv                          
     EEA20043.1 152 ChalvpielqsisqsadspesinmateleriqylgktqcshsHNPLSAHFELHIEQGPLLERTRKKVGVVegvqgmrwysincrgkeahagatrma 247
                    044445666688889999999999999**************999*****************999******************************** PP

                    .................................................................................EEEEEEEEEESHEEE CS
                    .................................................................................xxxxxxxxxxxxxxx RF
  Peptidase_M20 116 .................................................................................kvevelleggapvtl 130
                                                                                                     +v++++ +  +  ++
     EEA20043.1 248 dradalvvlakfavkveelakkhdafgtvgvmrtktnsintvpggafctldlrhwsddtldlieselrtllkqqeeevpgiEVSMDRTWCKKNIRF 343
                    ******************************************************************************998888888899999999 PP

                    CCHHHHHHHHHHHHHHHTSC.EEEEEESSSBHTHHHHTTT.EEEEEEESSG.GCTTSTTTEEEHHHHHHHHHHHHHHHH CS
                    xxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxx.xxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_M20 131 ndsplvkalaeaaeelfgek.velivsgpggtdarffagi.ptvmifgpgs.glaHspnEyvdledlekgikvlarlle 206
                    + +  ++ +++aa +++ e+ v++++s  +g+d++  a++ pt+mif+p++ g++H+p E++ +ed+  g+ +l ++++
     EEA20043.1 344 D-QVARRCVRDAACATVDESlVMDMISY-AGHDSAETAHVvPTAMIFVPSKkGISHNPAEFTTEEDCDIGAHTLLKAVL 420
                    9.99999999999998877769999999.********8888*******9966*********************999886 PP

>> GFO_IDH_MocA  Oxidoreductase family, NAD-binding Rossmann fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.9   0.1   5.2e-15   1.9e-11      26     118 ..     468     568 ..     446     570 .. 0.89

  Alignments for each domain:
  == domain 1  score: 44.9 bits;  conditional E-value: 5.2e-15
                   E...EEEEEECSSHHHHHHHHHHTTHE.....EESSHHHHHTCTTESEEEE-S-GGGHHHHHHHHHHTT-EEEEESSS-SSHHHHHHHHHHHHHHTS CS
  GFO_IDH_MocA  26 e...evvalldpdaeraeavaesfgve.....aysdleelladpeidavivatpngtheelakaaleagkhvllEKPlattveeakelvelaekkgk 114
                       +++al++++  +a+ + ++++++     ay + ++l+adp++++v+ +t+ ++h+e ++  ++a k+v++E P+a +++ ++elv++ + +g+
    EEA20043.1 468 KdlfQITALCNSSVDAAKSAIQQYHLDpsavkAYGNPADLAADPDVELVLCITRVDKHYETILPSIKAEKSVFIEWPIASSIANIEELVAAYQANGN 564
                   2445****************9999999998889**************************************************************99 PP

                   -EEE CS
  GFO_IDH_MocA 115 lvsv 118
                   + +v
    EEA20043.1 565 KSQV 568
                   8766 PP

>> M20_dimer  Peptidase dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.2   0.0   1.4e-08   5.1e-05       4     107 ..     225     324 ..     223     326 .. 0.82

  Alignments for each domain:
  == domain 1  score: 23.2 bits;  conditional E-value: 1.4e-08
                 -EEEEEEEEEE-B-EEGG-TTTTB-..HHHHHHHHHHCSCTTEEC.....TCCTCCCCCEECCE-C.CCCEESSEEEEEEEEEHHHHHHHHHHHHHHHH CS
   M20_dimer   4 kGlaggkitvkgkagHsgapgagaN..AieklarllaeledeegdiaeerslprttlnvtgiegGs.aknvipdeaeakidiRllpgedpeevleeiee 99 
                  G+ ++ i ++gk +H+ga   ++   A+  la++  + e++ ++       +  t  v++ +  + ++n++p+ a +++d+R    ++++ ++ e+++
  EEA20043.1 225 QGMRWYSINCRGKEAHAGATRMADRadALVVLAKFAVKVEELAKKHD-----AFGT--VGVMRTKTnSINTVPGGAFCTLDLRHWSDDTLDLIESELRT 316
                 7999**************6666654459**************66533.....4444..4444444459******************************* PP

                 HHTSCCST CS
   M20_dimer 100 ilekeape 107
                 +l+++ +e
  EEA20043.1 317 LLKQQEEE 324
                 **998765 PP

>> Peptidase_M28  Peptidase family M28
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   7.1e-06     0.025       1      95 [.      63     156 ..      63     198 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 7.1e-06
                    EEEEEESTTCE.SEEEEEEEE--B-TTTTCCT---TTTTHHHHHHHHHHHHHCHHGGCCSSEEEEEEEESSCSG.....SSHHHHHHHHHHCCCTT CS
  Peptidase_M28   1 Nviatlegkat.devlllgAHyDsvgvgrgpifvGAdDnAsgvaalLelarvlaasgsrpkrgvrflffdaEEa.....gllGSkafakakpelkk 90 
                    N+ a l+g+++  + + +g+H+Ds +        G  D   gv a L+++rv+++ + +    +  + ++ EE       + GS  +   +++l++
     EEA20043.1  63 NIFAILPGENNsIQPIGMGSHLDSQPA---G---GRFDGILGVIAALQVLRVIKEYNIKTYAPIAAIDWTNEEGsrfpkMCSGSGVWS-GTEKLSE 151
                    899999988876779***********6...5...7789999**************998999************988888888888777.5555665 PP

                    EEEEE CS
  Peptidase_M28  91 iaavl 95 
                    ++a++
     EEA20043.1 152 CHALV 156
                    55555 PP

>> Homez  Homeodomain leucine-zipper encoding, Homez
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   9.9e-06     0.036      11      48 ..       8      46 ..       2      51 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 9.9e-06
       Homez 11 iqPLekYysqhgllqekDldkLckkskl.saqqVrdWFa 48
                +  L++Y sq gll +    +Lc++s   s  qVrdWF 
  EEA20043.1  8 VWDLIQYTSQWGLLNDGGEVGLCRESLTnSDRQVRDWFV 46
                556999********************653889******6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (822 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       479  (0.0267165); expected 358.6 (0.02)
Passed bias filter:                      460  (0.0256568); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.64u 0.30s 00:00:00.94 Elapsed: 00:00:00.47
# Mc/sec: 5312.45
//
Query:       EEA20044.1  [L=245]
Description: DUF341 family oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.4e-25   87.5   0.0    1.5e-24   86.9   0.0    1.3  1  FSH1      Serine hydrolase (FSH1)


Domain annotation for each model (and alignments):
>> FSH1  Serine hydrolase (FSH1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.9   0.0   8.4e-29   1.5e-24       6     209 ..       2     229 ..       1     232 [. 0.84

  Alignments for each domain:
  == domain 1  score: 86.9 bits;  conditional E-value: 8.4e-29
        FSH1   6 kiLcLhGytqsgeiFraktsalrkllkk.lnvelvyldaplelaekadlpkseseeeekseeeeesraWfrkkde........................ 79 
                 + LcLhG   + +  + +++ lrk+l++ + +++++++ap+ +++++ ++++            + + W+  +                          
  EEA20044.1   2 QFLCLHGAIGNVDNISIQLEPLRKELESdQAATFHFINAPVTVDPPEGFTEY--------FGPGPHYRWMDDEGAgeesminrirrlpsgqnpedvmrs 92 
                 57*************************97889***********999989877........555555555555554555555555556666667777777 PP

        FSH1  80 ....kneyegleesldavkdyikengpfdGiiGFSqGaalaal.laslleellkeashpslkfailvsGfkleepkyeeyy.eedki..qtptLhvlGe 170
                     +++ ++ e  ++++ d+++e+ ++ Gi+G+S+G+a+aa+ ++ ++++l+ke +  ++k+ai++ G  + +p+ e    +e++i   +ptLh++G 
  EEA20044.1  93 latsDKAWRNRETVMQYLYDTLEEHPEVEGIVGYSEGSAMAATlILDEVHRLHKEGRPRRIKCAIFFTGWPPVSPDNELVLsDESEIilDVPTLHIVGA 191
                 77777899999999**************************975167888888888788889***********99987776675555568********** PP

        FSH1 171 lDtvvdeerseaLaeafkns.skvlkHpggHfvPnkkeyv 209
                 +D       + aL+++++ + ++++    gH +P++ + +
  EEA20044.1 192 NDPYRY--GALALYNVCDADtANMFDTGKGHTIPRTGKVI 229
                 ***999..99*********99*************987765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (245 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       401  (0.022366); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 1618.52
//
Query:       EEA20045.1  [L=2263]
Description: polyketide synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.1e-71  240.4   0.0    3.6e-71  239.7   0.0    1.4  1  ketoacyl-synt    Beta-ketoacyl synthase, N-terminal domain
    1.4e-65  220.6   0.2    4.3e-65  219.0   0.1    2.0  2  KR               KR domain
    2.1e-47  162.2   0.1    5.3e-47  160.9   0.0    1.7  2  Acyl_transf_1    Acyl transferase domain
    4.7e-46  157.4   0.0    7.6e-46  156.7   0.0    1.3  1  PS-DH            Polyketide synthase dehydratase
    4.3e-39  133.2   0.2    2.4e-38  130.8   0.1    2.5  1  Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
    5.7e-19   68.3   0.7    1.6e-18   66.9   0.0    2.1  2  adh_short        short chain dehydrogenase
      3e-16   59.9   0.0      9e-16   58.3   0.0    1.8  1  KAsynt_C_assoc   Ketoacyl-synthetase C-terminal extension
    6.3e-14   52.1   0.0    3.3e-13   49.8   0.0    2.2  2  ADH_zinc_N       Zinc-binding dehydrogenase
      1e-13   52.5   0.0      5e-13   50.2   0.0    2.2  2  ADH_zinc_N_2     Zinc-binding dehydrogenase
    1.1e-10   41.5   0.0    3.9e-10   39.7   0.0    1.9  2  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    2.9e-06   27.1   0.4    8.2e-06   25.7   0.4    1.8  1  ADH_N            Alcohol dehydrogenase GroES-like domain
    3.2e-06   27.4   1.3      1e-05   25.8   1.3    2.0  1  PP-binding       Phosphopantetheine attachment site
     0.0046   16.4   0.0     0.0096   15.3   0.0    1.4  1  Thiolase_N       Thiolase, N-terminal domain
  ------ inclusion threshold ------
       0.01   15.0   0.0      0.022   13.9   0.0    1.5  1  Polysacc_synt_2  Polysaccharide biosynthesis protein
       0.02   14.8   0.6      0.073   12.9   0.6    2.0  1  ACP_syn_III      3-Oxoacyl-[acyl-carrier-protein (ACP)] synth
      0.091   12.1   0.0       0.16   11.3   0.0    1.4  1  GDP_Man_Dehyd    GDP-mannose 4,6 dehydratase


Domain annotation for each model (and alignments):
>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  239.7   0.0   3.2e-74   3.6e-71       3     253 .]      31     281 ..      29     281 .. 0.94

  Alignments for each domain:
  == domain 1  score: 239.7 bits;  conditional E-value: 3.2e-74
                    -EEEEEEEEEBTTBSS.HHHHHHHHHTT---EEES-TTSSCGTTSBTSSTTEEE-BSS.EEE..S..TTEGGTTSTHHHHHHHCTS-HHHHHHHHH CS
  ketoacyl-synt   3 pvaivGmgarfPggnd.veefwelLlegrdaiselpadrwdadklydpparaagkiktklggfld..vddfdpeffgispreaeamdpqqrlllea 95 
                    ++ai+G ++r+Pg+++ + ++wel  ++r++ s++p+dr+  +++++p++   g  +   g+fl+  +++fd+ ff+i+++ea++mdpqqrllle+
     EEA20045.1  31 RIAIIGYACRLPGAVSsPTDLWELCTRKRSGWSPIPKDRFASEAFHHPNPSKVGSFNPGGGYFLKddISHFDAPFFNITAQEATSMDPQQRLLLEC 126
                    8***************9*****************************88888888888889****99****************************** PP

                    HHHHHHHHTS-HHTCTTGGEEEEEEESSTHHHHHHHHHHHTTGGGSCTTHHHHHSTTHHHHHHHHHHT--SSEEEEESGGGHHHHHHHHHHHHHHT CS
  ketoacyl-synt  96 awealedagltpeeldgsrvgvfiGvgagdyaalaaldedgsevkaspkavgavlanviagrisyalglrGpsvtvdtACsSslvavhaavqslrs 191
                    ++ea+e+ag+++e+l+g++vgvf+G + +dy+ +++ d ++     +  a+g+ +++  ++risy +++rGps+tvdtACsSslva+haavqslrs
     EEA20045.1 127 SYEAIESAGIPKESLSGRNVGVFVGGNLADYELHNVRDVET--IPMYQ-ATGC-APSLQSNRISYYFDFRGPSFTVDTACSSSLVALHAAVQSLRS 218
                    *******************************6444444333..55666.8998.****************************************** PP

                    TS-SEEEEEEEE---SHHHHHHHHHTTBB-TTSGGGTTBTTB.-SB-BB-EEEEEEEEECHHH CS
  ketoacyl-synt 192 geadvalaGGvellltpeavagfsaagllspdgrckafdpka.dGfvlGEGvGavvLkrleda 253
                    ge+  al+ G  l + p  ++++s+ +l++++g++ afd++a +Gf +GEG+++v+Lk+l+da
     EEA20045.1 219 GESTEALVAGCRLNIVPDLFVSMSMSQLFNDEGKTYAFDNRAtSGFARGEGAAVVLLKPLDDA 281
                    ************************************************************997 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.0       9.4   1.1e+04      76      98 ..     282     304 ..     278     308 .. 0.79
   2 !  219.0   0.1   3.8e-68   4.3e-65       1     179 [.    1897    2075 ..    1897    2076 .. 0.99

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 9.4
                 HHHSS---EEEE---------TT CS
          KR  76 kaeeppikGvihaAgvlrdklle 98 
                  ++++pi+ vi   gv++d+  +
  EEA20045.1 282 IRDKDPIRAVIVNSGVSQDGRTQ 304
                 46778************998765 PP

  == domain 2  score: 219.0 bits;  conditional E-value: 3.8e-68
                  SEEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------T CS
          KR    1 gtylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdkll 97  
                  +tylitGG+GgLG+++a+w+  kgar++vl+sRs+ ++++ +ali+el++ g++v v a+Dvs++++ve ll+   ++ pp++Gv+h A+vlrd l+
  EEA20045.1 1897 ATYLITGGTGGLGRSMAKWMSTKGARNIVLVSRSGFVNDKLEALIRELASEGTQVLVKACDVSSRADVEGLLNGELTHLPPVRGVVHGAMVLRDILF 1993
                  79**************************************************************************99******************* PP

                  TT--HHHHHHHHTTTTHHHHHHHHHTTTS--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHHHHHTEEEEEE--BT CS
          KR   98 eemtaedleqvlapKvkGawnLhelledesldffvlfSSiagllgsagqanYaaaNaflDalaeyrrsqglpavsinwglwa 179 
                  e+mt ed+++v a Kv+GawnLh+ l++++ldff+++SSiag++g++gqa+Y+aaN flD++++yr+sqglp+ si++ +++
  EEA20045.1 1994 ENMTLEDFQSVSACKVEGAWNLHHSLAQSPLDFFITLSSIAGVVGNRGQAAYSAANVFLDGFMQYRQSQGLPGKSIDLAAVT 2075
                  ******************************************************************************9886 PP

>> Acyl_transf_1  Acyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  160.9   0.0   4.7e-50   5.3e-47       2     299 ..     567     882 ..     566     900 .. 0.84
   2 ?   -2.7   0.0       2.9   3.3e+03     160     189 ..    1930    1959 ..    1928    1962 .. 0.88

  Alignments for each domain:
  == domain 1  score: 160.9 bits;  conditional E-value: 4.7e-50
                    EEE--TT---TTTTCCHHHC-HHHHHHHHHHHHHCCH.HHT--HHHHHHS-.-TTGGGSHHHHHHHHHHHHHHHHHHHHHTT-TTSEEEE-TTHHH CS
  Acyl_transf_1   2 fvfsGqGsQwaGMGmeLlktskafaaviaradeafks.qygfsvldvlrnn.peglldaiqfvqpaLaavqialaellkskGvrpaavvGHSlGEl 95 
                    +vf+GqG+Qwa MG  L+++ ++f+a+i++ad  +++ ++ +s+ + +++   ++++d  + +qp+ +a+qial+ ll s G rp  vvGHS GE+
     EEA20045.1 567 YVFTGQGAQWAQMGCTLMNEYPIFKAAIRQADDCLRQlHAEWSLEEEIKKDlANSQIDTPELSQPGCTAIQIALVILLDSWGIRPNYVVGHSSGEI 662
                    9**********************************984689***99887761447899999*********************************** PP

                    HHHHHCCSSSHHHHHHHHHHHHHHHHHH...T..S-EECCEECS...HHHHHHH....TT.EEEEEEECCCCECCEEHHHHHHHHHHHHHCC.CCE CS
  Acyl_transf_1  96 Aaavvagalsseeallavvlrsrlmmql...a..gpgdmaavel..aeeeeklr..cqddvvgavansprrvvisgsqealrelvervskegvgal 182
                    Aa  +aga  +   +   + r+++++ l   +  + g+m av+    +++++l+       ++a++nsp +v++sg   a++el   ++ ++++ +
     EEA20045.1 663 AASFAAGAYDLQATMALSYYRGQMTRLLketHpsLRGGMIAVGAgaRTVRPMLKmlHAGYATVACVNSPASVTVSGDIPAIEELESILQTRQIFNR 758
                    ********9888777777777766543322234478*******9987778888754667789********************************** PP

                    EECCCEECTTCCCCCCCCHHHHHHHHCCCHHC...HHTTBEHCCCHHHHHHCHHHHHHHHHHHCHCCHCCHHTTS..SSEC.C-CCEECSSSSCCH CS
  Acyl_transf_1 183 venvnvavhspqvdaiadalasaladiaprkp...kvakisstsldesserelsaeywvanlrspvrfaeavlsa..aeti.plvfveispHslll 272
                    + +++va hs  +++i +a    + +i p+ +    v + ss+  + +++  l a+yw +nl spv+f +a+ ++   + + p+  +e+ pH+ l 
     EEA20045.1 759 RLKIDVAYHSDHMKKISEAYFTSIEHIQPNSAlqnDVIFFSSVLGRVAEPSALNAAYWIQNLTSPVLFPDALEQMckQDGGyPNLLIEVGPHAALK 854
                    **************************9998653337888999999999**************************986454437899*********9 PP

                    CCCCCCCHHGGG-TCCCC..CCTEETTSS CS
  Acyl_transf_1 273 aalektlksaedvksatl..vGklkrdlt 299
                      + + lk+  +  +a++  ++++ r  +
     EEA20045.1 855 GPIGDILKN-LGLTPARIayAPTIVRKEN 882
                    988888885.5555554411455555555 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 2.9
                     CCEEHHHHHHHHHHHHHCC.CCEEECCCEE CS
  Acyl_transf_1  160 isgsqealrelvervskegvgalvenvnva 189 
                     +++ +++l++l+++++ eg ++lv++ +v 
     EEA20045.1 1930 SGFVNDKLEALIRELASEGTQVLVKACDVS 1959
                     57899**************99999999886 PP

>> PS-DH  Polyketide synthase dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  156.7   0.0   6.8e-49   7.6e-46       3     259 ..     953    1232 ..     951    1270 .. 0.84

  Alignments for each domain:
  == domain 1  score: 156.7 bits;  conditional E-value: 6.8e-49
                  TB.-EE--.-SS-EEEEEEE-S-SS.TTTSEEETTEEB--TTHHHHHHHHHHHHTS---.....-EEEEEEEE----.B--SS-EEEEEEEEE-TTS CS
       PS-DH    3 llGsrvrsasdkevvfrnrlrlaelpwLrDHrvdgkvvlPgagylemaleAarqltges....kavelrdvsilkalvlpedepvevqlslepeedg 95  
                  +lG     ++d e+++rn +rl+++pwLrDH+++g vv+P  gyl+maleAa++ + +     +a+e+r+v++++alvl++d  ve ++sl+p ++g
  EEA20045.1  953 VLGVMANYSNDMEPTWRNIMRLDDMPWLRDHKMQGMVVYPLSGYLAMALEAAARRAHQRnitfAAFEFREVVVESALVLNDDIDVETTISLRPYDEG 1049
                  5676677789****************************************999988777899******************999***********888 PP

                  -E.......EEEEEEE-SS-TT.EEEEEEEEEE-----...........--B--HHHHHHHS-SEE....E-HHHHHHHHHHHSEEE-GGG--EEEE CS
       PS-DH   96 ad...rawvefeifSregggeewtehatGtvrlaegaa...........aaavdlealqarcaepaslrsvssaefYerlaargleyGpsFqglral 178 
                  +    + w ef+i+S++++ + w +h++G v ++++             + +  +++  +++  + s++ v++ ++Y+ l++ g +yGp+F+gl++ 
  EEA20045.1 1050 TRgasDVWDEFKIHSWSSQRG-WIKHCHGLVGVRNSFYgdasgvfgsglKNRSHIQNQ-KSKILSCSTNHVPEGRLYQVLTDLGADYGPTFKGLENC 1144
                  77**999*************8.**********98776688899999777666666666.44444556789*************************** PP

                  EEETTEEEEEE---....GGGSSTTTT-SB-HHHHHHHHHHG..GG----------EEEEEEEEEEE-S....-BTS--EEEEEE..- CS
       PS-DH  179 wrgdgealaelrlp....eelaggesayvlhPallDaalQllaaalsaeaekadaaylPvaierlrvyr.pssaageelwvharl..e 259 
                  +++ +   a+l +      + ++ +s++++hPa lD +l+l+   l+  +   +++y+P+ i++  ++   s ++g+++++  +   +
  EEA20045.1 1145 YADSNHSHAHLYIRdttsLMPKNFQSPLFVHPAFLDGLLHLVWPILGHGRMTLETLYMPTLIKHAIISSdISLTPGQHVRAFGTGspN 1232
                  **9999999999985544444445555999**********998888777899***************999999999999998887553 PP

>> Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  130.8   0.1   2.2e-41   2.4e-38       2     117 ..     290     406 ..     289     407 .. 0.98

  Alignments for each domain:
  == domain 1  score: 130.8 bits;  conditional E-value: 2.2e-41
                      EEEEEEEEEE--STSSSTSTTHHHHHHHHHHHHHHHT--GGGEEEEE-SS-SSHHHHHHHHHHHHHHHGGGGG.SCTSEEE-THHHH-B-GGGH CS
  Ketoacyl-synt_C   2 avikgsavnsdgahnsltapngeaqaraiekalaeagvdpedvdyveahgtgtplgDpiElealkkvfgekar.kqplavgSvKsniGHleaAa 94 
                      avi++s+v++dg+++++t+png+aq+++i+++++ea+++ped + ve+hgtgt++gDpiE++a+++++g++++ k+pl++gSvKsn+GHle+A+
       EEA20045.1 290 AVIVNSGVSQDGRTQGITSPNGRAQEELIRRVYNEAHIEPEDCGFVEMHGTGTKVGDPIEATAVHAALGHGRSpKNPLYIGSVKSNVGHLEGAS 383
                      9*********************************************************************999********************* PP

                      HHHHHHHHHHHHHHTEE--BTT- CS
  Ketoacyl-synt_C  95 Gvaelikvvlalkhgvipptlnl 117
                      Gv++lik++++l h+ + p++ +
       EEA20045.1 384 GVVSLIKAAMMLDHDLLLPNADF 406
                      *******************9876 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.1       3.1   3.5e+03       3      33 ..    1690    1721 ..    1688    1732 .. 0.79
   2 !   66.9   0.0   1.4e-21   1.6e-18       3     164 ..    1899    2060 ..    1897    2079 .. 0.92

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 3.1
                  EEEESTTSHHHHHHHHHHHHTT-EEEE.EESC CS
   adh_short    3 vlvtGassGIGraiakelakeGakvvv.vdrs 33  
                  vl+  +++G+G+a  +     Ga+++v v+++
  EEA20045.1 1690 VLIHAGAGGVGQAAIQLAQMVGADIYVtVGSH 1721
                  89999*******99999988999999944444 PP

  == domain 2  score: 66.9 bits;  conditional E-value: 1.4e-21
                  EEEESTTSHHHHHHHHHHHHTT-EEEE.EESC...HHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGG CS
   adh_short    3 vlvtGassGIGraiakelakeGakvvv.vdrs...eekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfse 95  
                   l+tG+++G+Gr +ak + ++Ga+ +v v+rs   ++kle+++ el +eg+++l+ ++Dv++r++ve l++    +l ++  +v++A + ++  f++
  EEA20045.1 1899 YLITGGTGGLGRSMAKWMSTKGARNIVlVSRSgfvNDKLEALIRELASEGTQVLVKACDVSSRADVEGLLNGELTHLPPVRGVVHGAMVLRDILFEN 1995
                  59**********************9998999755579************************************************************ PP

                  CSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHH CS
   adh_short   96 lseeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrsla 164 
                  ++ e++++v ++ + g+ +l +++++          ++ sS+ag v++ g+aaYsA+  +++g+++  +
  EEA20045.1 1996 MTLEDFQSVSACKVEGAWNLHHSLAQS----PLDFFITLSSIAGVVGNRGQAAYSAANVFLDGFMQYRQ 2060
                  **********************99888....44689****************************98655 PP

>> KAsynt_C_assoc  Ketoacyl-synthetase C-terminal extension
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.3   0.0   8.1e-19     9e-16       2      84 ..     410     504 ..     410     534 .. 0.85

  Alignments for each domain:
  == domain 1  score: 58.3 bits;  conditional E-value: 8.1e-19
  KAsynt_C_assoc   2 npeipaleegrlkVvteptpwpggi..vgvNsfGfGGsnvHviLksnk.......kekrkeesk...........eeslprLlvlsgrteeavea 76 
                     n +ip l+e+++kVvt++ pwp+g   ++v+ +GfGG+n+Hv+L++++               +           ++++++L+ +s++++e++++
      EEA20045.1 410 NVNIP-LTEWNMKVVTSTRPWPRGKkfISVSNYGFGGTNAHVVLEKAPltlnlpdA-------TstdaddnlhmyNDPKHKLIFISANDKESLQQ 496
                     6789*.******************99**********************77755431.......2233456788999******************* PP

  KAsynt_C_assoc  77 llekleeh 84 
                      ++++  +
      EEA20045.1 497 RIKDFGIY 504
                     99987655 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.8   0.0   2.9e-16   3.3e-13       1      97 [.    1698    1798 ..    1698    1829 .. 0.83
   2 ?   -1.7   0.0       2.4   2.7e+03      70      93 ..    1884    1907 ..    1870    1944 .. 0.78

  Alignments for each domain:
  == domain 1  score: 49.8 bits;  conditional E-value: 2.9e-16
                  HHHHHHHHHHHHTT-EEEEEESSHHHHHHHHH.TT..ESEEEETTTC.HHHHHHHHHTTTSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSC..T CS
  ADH_zinc_N    1 gvGlaavqlAkalGaeviavdsseeklelakk.lG..adevinykea.dlverikeltggegvdvvfecvGsgatleaalkllkpgGrlvvvGg..g 91  
                  gvG+aa+qlA + Ga ++++++s++k+ ++ + +    d+++ + ++ ++  +++++tg egvdvv++ ++ g+ l+++ ++l+p Gr+  +G    
  EEA20045.1 1698 GVGQAAIQLAQMVGADIYVTVGSHDKRSFLIQrYNipEDRILYS-RDnSFGPAVRRATGNEGVDVVLNSLA-GDLLRESWDCLAPFGRFIEIGKadI 1792
                  9**************************99888676547888887.6559**********************.*********************7554 PP

                  SSEEEE CS
  ADH_zinc_N   92 kgeeef 97  
                  ++++ +
  EEA20045.1 1793 TKNSRL 1798
                  444433 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 2.4
                  HHHHHHHHCEEEEEEEEECSCTSS CS
  ADH_zinc_N   70 atleaalkllkpgGrlvvvGggkg 93  
                   +l+++++ll+++ +  + Gg +g
  EEA20045.1 1884 VSLKTSVNLLQKNATYLITGGTGG 1907
                  678999999999999999998333 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.2   0.0   4.5e-16     5e-13      13     133 .]    1749    1873 ..    1736    1873 .. 0.83
   2 ?   -2.2   0.0       7.3   8.2e+03      35      99 ..    1886    1946 ..    1879    1954 .. 0.60

  Alignments for each domain:
  == domain 1  score: 50.2 bits;  conditional E-value: 4.5e-16
                    THHHHH-TT-EEEEEES-HHHHH.HHHHHHEEEEEEEEE--.--.S-EEE-CHHHCTTT-EEEE--GGG...-....-HHHHHHHHHHHHHHH-- CS
  ADH_zinc_N_2   13 dfeaatggegvDvvldtvggealleaslkvlpggGrlvsig.gpplsaallkpakkrkgrsvkyeflfsmkas...aqadileelaalieeGklr 103 
                    ++++atg+egvDvvl++++g+ l ++s+++l++ Gr+++ig ++++++  l+  k++ + ++  + l+++ ++     +++l+++++l+ e++++
    EEA20045.1 1749 AVRRATGNEGVDVVLNSLAGDLL-RESWDCLAPFGRFIEIGkADITKNSRLEMLKFEHNVTFASVDLTKVAKFrpkLMKRLLNDVCRLLGENTIK 1842
                    3449999**************98.*******999*******6666555555555557777777777777666688888999************** PP

                    --EEEE.EEGGGHHHHHHHHHSS--SSEEEE CS
  ADH_zinc_N_2  104 pvvdrv.fpleeaaeAhrylesgrarGKiVl 133 
                    p    + + ++e+   +r+l++g+ +GK V+
    EEA20045.1 1843 PIYPITkYAISEVEAGLRALQTGKNMGKSVV 1873
                    **99888*********************998 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 7.3
                    H.HHHHHHEEEEEEEEE----.S-EEE-CHHHCTTT-EEEE--GGG...-.-HHHHHHHHHHHHH CS
  ADH_zinc_N_2   35 lleaslkvlpggGrlvsiggpplsaallkpakkrkgrsvkyeflfsmkasaqadileelaaliee 99  
                    l + s+++l+++++++  gg+    + ++ +++  +++++++++  ++ +   d le+l + +++
    EEA20045.1 1886 L-KTSVNLLQKNATYLITGGT-GGLGRSMAKWMSTKGARNIVLVS-RSGF-VNDKLEALIRELAS 1946
                    4.7888999777998555543.34444555555666777776666.6666.55557777666555 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0         4   4.5e+03       5      60 ..    1745    1802 ..    1744    1816 .. 0.72
   2 !   39.7   0.0   3.5e-13   3.9e-10       4     154 ..    1906    2058 ..    1903    2065 .. 0.83

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 4
                    SHHHHHHHHHHHTT-EEEEEESSGGH.HHHHHHHHHHTTSE..EEE--TTSHHHHHHHH CS
  adh_short_C2    5 gIGraiAkalaeeGaevvltdlneea.kkrveelaeelgae..vlecDVtdeeqvealv 60  
                    + G a+ +a  +eG +vvl  l  ++ +++ + la  +g+   + ++D+t+++ +e l 
    EEA20045.1 1745 SFGPAVRRATGNEGVDVVLNSLAGDLlRESWDCLAP-FGRFieIGKADITKNSRLEMLK 1802
                    67778888899999****999999996666665555.6655235899999888887665 PP

  == domain 2  score: 39.7 bits;  conditional E-value: 3.5e-13
                    TSHHHHHHHHHHHTT-E.EEEEESSGGHHHHHHHHHHHTTSE.....EEE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-H CS
  adh_short_C2    4 sgIGraiAkalaeeGae.vvltdlneeakkrveelaeelgae.....vlecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsr 92  
                     g+Gr +Ak +  +Ga+ +vl+ ++   ++++e+l +el +e     v +cDV+++++ve l +    ++  + ++v+ a + ++    f++++ 
    EEA20045.1 1906 GGLGRSMAKWMSTKGARnIVLVSRSGFVNDKLEALIRELASEgtqvlVKACDVSSRADVEGLLNGELTHLPPVRGVVHGAMVLRD--ILFENMTL 1998
                    599*************866666654443555555555544333222459**********************************99..******** PP

                    HHHHHHHHHHTHHHHHHHHHHHHHCTSCCEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHH CS
  adh_short_C2   93 eefdraldvnlyslfllakaalplmkeggsivnlssvgaervvpnynaygaaKaalealtry 154 
                    e+f+ + + ++ ++++l + +++   +    ++lss+++ ++  +++ay+aa   l ++++y
    EEA20045.1 1999 EDFQSVSACKVEGAWNLHHSLAQS--PLDFFITLSSIAGVVGNRGQAAYSAANVFLDGFMQY 2058
                    *****************9987653..3378**********************9999888776 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.7   0.4   7.3e-09   8.2e-06       2      70 ..    1581    1644 ..    1580    1659 .. 0.87

  Alignments for each domain:
  == domain 1  score: 25.7 bits;  conditional E-value: 7.3e-09
                  TEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS--TT-EEEE-SEEE-SSS CS
       ADH_N    2 gevlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkklkvGdrVvvepliscgeC 70  
                  + v i+v+a+gi+  D+ +  g    + ++p  +G E +G+v +vg++v ++  G+rV++ p  + ++ 
  EEA20045.1 1581 DSVEIEVQATGINFKDVVVSMG----QLNQP-YIGVECSGIVTSVGKNVVDVLPGQRVMAMPEGAYSTY 1644
                  789**************99999....68889.68*************************9887665554 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   1.3     9e-09     1e-05       2      67 .]    2188    2253 ..    2187    2253 .. 0.94

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 9e-09
  PP-binding    2 klrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaayl 67  
                  +l + +a vl +++e++d +t  ++lGlDSl+a+e+ +++ +e +  + + +l+   +l  l++++
  EEA20045.1 2188 ALAAKLAIVLSMAPEDMDISTRVSSLGLDSLVAIEIRNWIAREVDANVQVLELLSSESLTKLSELI 2253
                  678888999**************************************************9999876 PP

>> Thiolase_N  Thiolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   8.6e-06    0.0096      77     112 ..     194     229 ..     183     231 .. 0.92

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 8.6e-06
                 EEEEEEHGGGHHHHHHHHHHHHHHTTSHSEEEEEEE CS
  Thiolase_N  77 pavtvnkvcsSglkavalaaqsiaageadvvvagGv 112
                 p+ tv+ +csS+l a+++a+qs+++ge+  +++ G+
  EEA20045.1 194 PSFTVDTACSSSLVALHAAVQSLRSGESTEALVAGC 229
                 788************************998888885 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0     2e-05     0.022       2      74 ..    1900    1969 ..    1899    2002 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 2e-05
                       EEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH......-TTEEEE....E--TT-HHHHHHHTT CS
  Polysacc_synt_2    2 lvtGagGsiGselvrqilkkkpkkiillerdElklyeiekeleeelkkkklkveivpvigdvrdkerlekale 74  
                       l+tG++G +G+++ + + +k +++i+l++r+ +  +++e  ++ el+++ +  ++++  +dv  ++ +e +l+
       EEA20045.1 1900 LITGGTGGLGRSMAKWMSTKGARNIVLVSRSGFVNDKLEALIR-ELASEGT--QVLVKACDVSSRADVEGLLN 1969
                       8********************************9999999765.4444444..45567888888888877665 PP

>> ACP_syn_III  3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.6   6.5e-05     0.073       2      34 ..     197     229 ..     196     284 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 6.5e-05
                  EEE-GGGHHHHHHHHHHHHHHTTS-SEEEEEEE CS
  ACP_syn_III   2 DlnaaCsgfvyalsvAdaliesgaakrvLviga 34 
                   + +aCs+ ++al+ A + ++sg+  ++Lv g 
   EEA20045.1 197 TVDTACSSSLVALHAAVQSLRSGESTEALVAGC 229
                  5789**************************996 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00015      0.16       1      71 [.    1900    1968 ..    1900    1972 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00015
                     EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHH CS
  GDP_Man_Dehyd    1 LiTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkgDltDssslerll 71  
                     LiTG++G  G  +a+++ +kg + +++v rs  +n +++e+l ++  +   +++ +  +D++ ++ +e ll
     EEA20045.1 1900 LITGGTGGLGRSMAKWMSTKGARNIVLVSRSGFVN-DKLEALIRELAS-EGTQVLVKACDVSSRADVEGLL 1968
                     9************************9998877655.999999987654.4567888888999888888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2263 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       422  (0.0235373); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              16  [number of targets reported over threshold]
# CPU time: 1.10u 0.29s 00:00:01.39 Elapsed: 00:00:00.50
# Mc/sec: 13694.26
//
Query:       EEA20046.1  [L=159]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-20   73.2   0.0    2.4e-20   72.9   0.0    1.1  1  SnoaL_4   SnoaL-like domain


Domain annotation for each model (and alignments):
>> SnoaL_4  SnoaL-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.9   0.0   1.3e-24   2.4e-20       3     126 ..      15     142 ..      13     143 .. 0.92

  Alignments for each domain:
  == domain 1  score: 72.9 bits;  conditional E-value: 1.3e-24
                 HHHHHHHHHHHHHHHHHHHTT-HHHHHTTEEEEEEEEETTS..--EESHHHHHHHHHSHHHHHH-EEEEE---EEEE..ETTEEEEEEEEEEEEEETTE CS
     SnoaL_4   3 ledreaIrdlvarygyylDtkdweeladlFtedavvdytgvgegvlegrdairaalrealdgfaltqHllsnpliel..dgdtAtgrayllatlvrdgd 99 
                 l+ r+aI d+++r +  lDt+d e++++ Ft+ a++ ++     v eg  ai++ +++ +  +++t+H+l+n +i++   g++A +++++la+++r+g+
  EEA20046.1  15 LSGRDAIADVLYRLVLGLDTNDSELFDSAFTPTATFAIND---KVSEGLPAIHTDCFDGI-TKLDTTHFLTNIRITIddSGKKAAATSSALAQHYRGGK 109
                 67799**********************************6...8***************8.899*************644699***************7 PP

                 E....EEEE..EEEEEEEEEEE..TTEEEEEEE CS
     SnoaL_4 100 g....grqvlaggryedelvre..dggWrisrr 126
                 g     +++lag  y ++lv++  ++ W+i+ +
  EEA20046.1 110 GlepnQPRLLAGSLYYVDLVKDetSDLWKIHDF 142
                 776668999*************66778***987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (159 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       307  (0.0171231); expected 358.6 (0.02)
Passed bias filter:                      287  (0.0160076); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.44
# Mc/sec: 1075.89
//
Query:       EEA20047.1  [L=235]
Description: hypothetical protein PMAA_039140 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.22   11.8   0.1       0.36   11.1   0.1    1.3  1  TSLP      Thymic stromal lymphopoietin


Domain annotation for each model (and alignments):
>> TSLP  Thymic stromal lymphopoietin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.1     2e-05      0.36      93     124 ..      23      52 ..      13      53 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 2e-05
                 --------H.....HHHHHHHHHHHHHHHHHH CS
        TSLP  93 tqamkkrkkrevttnkCleqvsqllelWrrfs 124
                 +q+m    kr+ t+ kC+e  +q+l++Wrr +
  EEA20047.1  23 IQSMD--LKRDSTEPKCRELQTQILNMWRRIW 52 
                 55554..7899******************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (235 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       539  (0.030063); expected 358.6 (0.02)
Passed bias filter:                      479  (0.0267165); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.30s 00:00:00.83 Elapsed: 00:00:00.50
# Mc/sec: 1406.05
//
Query:       EEA20048.1  [L=216]
Description: hypothetical protein PMAA_039150 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00017   20.6   0.1       0.07   12.0   0.1    2.2  2  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.1   3.9e-06      0.07       6      61 ..      65     125 ..      60     129 .. 0.82
   2 !    6.9   0.0   0.00014       2.5     172     206 ..     129     163 ..     124     169 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 3.9e-06
                 HHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH........HHHHHHHTHHHHHHH CS
    Sugar_tr   6 alggllfgYdtgvigafltllkfaknfglsksksskee.....ssvlsglivsiflvGaii 61 
                 +++++lf Ydt  +g++ltl++f +nf  ++++++  +         + ++ +++ +G ++
  EEA20048.1  65 CISSFLFAYDTRAVGGVLTLQAFDTNFRDTNAQATRINynlftPVEFMAWCWCCYRLGPAV 125
                 7899***********************9999998887777776666677777777777666 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.00014
                 HHHHCCHHHHHHHHHHGGGS---HHHHHHTT-HHH CS
    Sugar_tr 172 illglqlvpallllilllflPESPrylvekgkeee 206
                 i++gl lv   l+ + +l++ ES r+l +kg +  
  EEA20048.1 129 IPIGLLLVRGGLIGLEMLLVKESVRWLEKKGSQRN 163
                 899999************************98874 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (216 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       361  (0.020135); expected 358.6 (0.02)
Passed bias filter:                      264  (0.0147247); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.46
# Mc/sec: 1417.61
//
Query:       EEA20049.1  [L=215]
Description: biphenyl-2,3-diol 1,2-dioxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    6.3e-07   29.6   0.0    9.1e-07   29.1   0.0    1.3  1  Glyoxalase  Glyoxalase/Bleomycin resistance protein/Dioxygena


Domain annotation for each model (and alignments):
>> Glyoxalase  Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.1   0.0   5.1e-11   9.1e-07       3     128 .]      19     140 ..      17     140 .. 0.89

  Alignments for each domain:
  == domain 1  score: 29.1 bits;  conditional E-value: 5.1e-11
                 EEEE..EEESHHHHHHHHHHHHHTSEEEEEEEEEESTEEEEEEEEETTTSEEEEEEEECCTTSCTHHCCBSC.....TSEEEEEEEEEHCHHHHHHHHH CS
  Glyoxalase   3 dhva..llvgdleksldFYtkvLGfklvkktdnteeteglriaffhaggghielvlneapsgaakhvkkiee.....tvhhvafialdvedvgkaldrl 94 
                 +hv+   + + ++ +++FY ++L++ +  +++        +iaf+  ++ h+ +++  +p+   ++     +     +  h+af++++  ++++ +  l
  EEA20049.1  19 AHVVfrTAPDKYKTMVNFYMQILNAIIRHEDP-------GKIAFLSFDEEHHRIAILAVPGIITPSP----TdipraGLDHIAFTYKSLTELAQLYVSL 106
                 566643344568889**************999.......99*********************99999....4445669********************* PP

                 HHTTGEEEEEEECHHCTEEEEEEEEETTSEEEEE CS
  Glyoxalase  95 keagvkvvaepgrhyfgalysfyfrDpdGillei 128
                 +++     +++     g   s y rDp G+++e+
  EEA20049.1 107 RDRQSDPLKPIWSINHGPTTSLYYRDPQGNKIEM 140
                 ****9999999999999999999*********95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (215 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       332  (0.0185175); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1513.62
//
Query:       EEA20050.1  [L=118]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.7e-33  114.0   0.1    4.4e-33  113.7   0.1    1.0  1  MPC       Mitochondrial pyruvate carriers
  ------ inclusion threshold ------
      0.013   15.5   0.1        6.1    7.0   0.0    2.3  2  LAB_N     Lipid A Biosynthesis N-terminal domain


Domain annotation for each model (and alignments):
>> MPC  Mitochondrial pyruvate carriers
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.7   0.1   4.9e-37   4.4e-33       4     102 ..      11     111 ..       8     117 .. 0.93

  Alignments for each domain:
  == domain 1  score: 113.7 bits;  conditional E-value: 4.9e-37
         MPC   4 rflnsetgkk..tvhFWaPvlkwglviaglsDlkrpaekiSltqnlaLlatgliwtryslvikPkNyllaavnfvlelvglvqvsRilkyrlskkdekk 100
                 r+ +++t+++  ++hFW+P++++g++ia++sD+++++e iS++++ a+++ +++ +rysl+++PkNyll+a+++v+  ++ +q++R++++++ ++++ +
  EEA20050.1  11 RIRSNKTLDYfcSTHFWGPASNFGIPIAAVSDIQKDPEIISGRMTGAFIVCSALLMRYSLAVRPKNYLLFAMHTVNVGAQSIQMMRFVNHWYLQERTPE 109
                 5667888888999********************************************************************************999877 PP

         MPC 101 ea 102
                 ++
  EEA20050.1 110 AV 111
                 65 PP

>> LAB_N  Lipid A Biosynthesis N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.0   0.00068       6.1      20      67 ..      14      61 ..       5      65 .. 0.79
   2 ?    6.6   0.0   0.00091       8.2       5      28 ..      89     112 ..      85     115 .. 0.87

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.00068
       LAB_N 20 sekkkksvlpvlFWvlSllGslllliYailrkDpvlilgqslglviyi 67
                s+k+    ++++FW      ++ + + + ++kDp +i g ++g++i +
  EEA20050.1 14 SNKTLDYFCSTHFWGPASNFGIPIAAVSDIQKDPEIISGRMTGAFIVC 61
                666666677888887666666777778889***************976 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.00091
       LAB_N   5 gqllFtlRfvvQwiasekkkksvl 28 
                 +q + ++Rfv  w++ e++ + v+
  EEA20050.1  89 AQSIQMMRFVNHWYLQERTPEAVV 112
                 789999************999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (118 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       342  (0.0190752); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.36u 0.26s 00:00:00.62 Elapsed: 00:00:00.40
# Mc/sec: 884.15
//
Query:       EEA20051.1  [L=596]
Description: phenol 2-monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.7e-77  260.4   0.0    3.4e-77  260.1   0.0    1.1  1  FAD_binding_3   FAD binding domain
    1.3e-45  155.4   0.0    3.3e-45  154.1   0.0    1.7  2  Phe_hydrox_dim  Phenol hydroxylase, C-terminal dimerisation d
  ------ inclusion threshold ------
      0.011   15.0   0.2      0.018   14.3   0.2    1.3  1  Thi4            Thi4 family
      0.016   14.3   0.0       0.19   10.7   0.0    2.1  1  SE              Squalene epoxidase
      0.033   13.8   0.3       0.73    9.4   0.3    2.3  3  DAO             FAD dependent oxidoreductase
      0.069   11.9   0.1       0.13   11.0   0.1    1.3  1  MCRA            MCRA family
      0.086   11.9   1.4       0.17   11.0   1.4    1.4  1  FAD_binding_2   FAD binding domain
       0.12   12.6   0.4       0.63   10.3   0.1    2.3  3  NAD_binding_8   NAD(P)-binding Rossmann-like domain


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  260.1   0.0   1.5e-80   3.4e-77       2     348 ..       6     365 ..       5     366 .. 0.89

  Alignments for each domain:
  == domain 1  score: 260.1 bits;  conditional E-value: 1.5e-80
                    EEEEEE--SHHHHHHHHHHHHTTHH...EEEEESSSSSCCSSS--EEEHHHHHHHHHTT-HHHHHHHSEECCCCEEEEEEE..........CCCCC CS
  FAD_binding_3   2 tdVlIVGaGpaGlmlallLseaGvr...vvlvekrsttvvlpradglnqrtmellrqlGledrilaegapnelmgealyne..........lsdtp 84 
                    +++++ GaG aGl +a+++++aG+      ++e+ +  ++ ++adg+++rt+e++++ Gl + +++e    ++ +  +++e          l +t 
     EEA20051.1   6 VPIIVCGAGSAGLCAATFMASAGIPaehIKILERNAGPMEIGQADGVQCRTVEVFESFGLSEPLIKES--YHVLEVCFWAEkedsgatpkqLVRT- 98 
                    78899*******************888788*************************************9..5666666666635555554444444. PP

                    EEEEEHHCHHCST-CEE--HHHHHHHHHHHHHHHT.EEETCSEEEECCEECCCCCCCEEE......ECCTTEEEEEEEEEEEE--GTT-HHHHHHT CS
  FAD_binding_3  85 karadlelesspervtvypqteleriLvehaeerg.lqvrfktevesleqdeegvtaevr......dketgeeetvrakYlvGaDGgrStvrktlg 173
                    ++ ad     s+    +++q +++ +L+++   ++ ++v+ + +v +++ d +g ++++          +g e+t+ra+Y+ G+DG++Stvr++lg
     EEA20051.1  99 RRTADTMPGLSHHPHVILNQARMNGMLLKKMHDEAgMEVEYGWNVSNVTVDFKG-DPDFPcvvvakRGIEGPETTMRARYVLGCDGAHSTVRRSLG 193
                    55555554799999999*********9999877666***********9999999.443332333446678999*********************** PP

                    GGEEEEEEEEEEEEEEEEEEC-SCCCTTCCEEEEECCTTEEEEEECCE.TEEEEEEEEECCE-GGGSCCCHHHHHHHHHHHHHHTTSSCEE.EEEE CS
  FAD_binding_3 174 iefegeetvyeagvldvlfdadlsdiveplvlilsaesrgvmviPlen.tlerfyvqvearaekeersekfteeevkarlreivgektldv.eiee 267
                     +++g +t+  +gv+dv ++++++di+++  + l+++s+ +m+iP+e  +l+rfy+ ++a++      + ++ e++++ +++i++++t+d  e  +
     EEA20051.1 194 YKMIGDSTDAVWGVMDVYPQTNFPDIRKK--ATLHTKSGNLMIIPREGdALVRFYIELQAGT----IAKSVSLEDLHRTAKQIFAPYTMDIaETMW 283
                    *****************************..7888888889*******88888888888776....788999******************99**** PP

                    EEEEEEEEEEESSSEET.TEEE-GGGTEEE-STTSHHHHHHHHHHHHHHHHHHHHHTTSS-GGGGHHHHHHHHHHHHHHHHH CS
  FAD_binding_3 268 vsawtvaqrvaekyrkg.rvflaGDAaHihpPtgGqGlNtaiqDavnLawkLaavlkGeAkeelLdtYeeerravaqavvdf 348
                     sa+ ++qr++++++k+ r+fl GDA+H+h+P++GqG+N+++qD +nL+wkLaa lkG+A +++LdtY  er++va+++++f
     EEA20051.1 284 WSAYSIGQRLVDHFHKDyRIFLTGDACHTHSPKAGQGMNVSLQDGYNLGWKLAAILKGQAPSSILDTYCLERQKVAADLIEF 365
                    *******************************************************************************998 PP

>> Phe_hydrox_dim  Phenol hydroxylase, C-terminal dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0         4   9.1e+03     117     143 ..     256     283 ..     249     302 .. 0.66
   2 !  154.1   0.0   1.5e-48   3.3e-45       1     166 []     395     562 ..     395     562 .. 0.98

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 4
  Phe_hydrox_dim 117 keieledlPevlrpfdeklgldy.ekvy 143
                     k+++ledl++  ++   ++ +d  e+++
      EEA20051.1 256 KSVSLEDLHRTAKQIFAPYTMDIaETMW 283
                     5677888888777776666666655554 PP

  == domain 2  score: 154.1 bits;  conditional E-value: 1.5e-48
  Phe_hydrox_dim   1 FtsGvgveYqpsllvaevkskqnlatglrpGrrlpsakVvrvaDanpvdlqdeipsdGrfRilvfagdlsdaeqksrlsaladalsskesflsrf 95 
                     +t+G++++Y++s+++++++s+++la+gl++G+r+ps +Vvr++Da+ ++l + +p+dGr+Ri+vfagd+s++++++rl++lad+lss+   +sr+
      EEA20051.1 395 YTAGLTAKYDDSVFTSTARSRSELARGLTVGMRFPSTQVVRLCDARAMQLVRAFPADGRWRIVVFAGDISTPTCSERLNNLADFLSSEAGPVSRI 489
                     89***********************************************************************************999999**** PP

  Phe_hydrox_dim  96 tpadadvdsvievllihaaprkeieledlPevlrpfdeklgl.dyekvyvddesyhe.dgaaYekyGidkkrG 166
                     tp++ad+dsvie +l+ +++  +ie +++Pe + p+++k+ + d  k +vd esy++ +g+ Ye+y idk++G
      EEA20051.1 490 TPSTADPDSVIEAILVLHSESGQIEQDQIPEHFTPVNGKWCIkDLFKTFVDCESYNSgHGHTYETYQIDKTEG 562
                     ******************************************999*********99966**********9987 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.2   7.9e-06     0.018      16      51 ..       4      41 ..       1      53 [. 0.88

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 7.9e-06
                TEEEEEEE--SHHHHHHHHHHHHC..TTS-EEEEESSS CS
        Thi4 16 aesDvvivGaGssGLtaayylakk..pdlkvailersv 51
                ++  +++ GaGs+GL aa  +a +  p  ++ iler+ 
  EEA20051.1  4 VKVPIIVCGAGSAGLCAATFMASAgiPAEHIKILERNA 41
                56679*****************9989999999999975 PP

>> SE  Squalene epoxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   8.6e-05      0.19       7     209 ..     180     377 ..     174     384 .. 0.56

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 8.6e-05
          SE   7 vcDGifsklRkels.dnkvevtssfvGlvlk..naelpkknkghvilgkpsp.vllYqisstetRilveikskklPs.iangelkeylkeevaPqlPke 100
                  cDG +s +R++l  +   + t+   G++    ++++p+ +k   + +k+   +++ + +   +R  +e+++ ++ + ++ ++l++  k+  aP+  + 
  EEA20051.1 180 GCDGAHSTVRRSLGyKMIGDSTDAVWGVMDVypQTNFPDIRKKATLHTKSGNlMIIPREGDALVRFYIELQAGTIAKsVSLEDLHRTAKQIFAPYTMDI 278
                 566666666666664444555555556544311333333333333333333203333334444555555555554431233444444444444443333 PP

          SE 101 lrksfkkaleegklrsmpnkflpasknekkGlillGDalnmRHPltggGmtvalnDivllskllkpledlsdeekvleelksfyvkRkeldavvnvLsi 199
                  +  + +a +         ++l  + ++   + l GDa     P  g Gm v l+D + l   l  +      ++ ++ l+++ ++R++++a +     
  EEA20051.1 279 AETMWWSAYS-------IGQRLVDHFHKDYRIFLTGDACHTHSPKAGQGMNVSLQDGYNLGWKLAAI---LKGQAPSSILDTYCLERQKVAADLIEFDR 367
                 3222222222.......234555556666778999*********************99999888888...44556677888888888888886666666 PP

          SE 200 alyslfaads 209
                  + s+f++++
  EEA20051.1 368 FFSSIFSSKK 377
                 6667776665 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.3   0.00032      0.73       2      30 ..       8      41 ..       7      51 .. 0.90
   2 ?    1.4   0.0     0.084   1.9e+02     114     259 ..      94     238 ..      48     287 .. 0.61
   3 ?   -3.4   0.0       2.4   5.4e+03      44      76 ..     422     452 ..     410     503 .. 0.64

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00032
                EEEECTSHHHHHHHHHHHHTT.....EEEEESSS CS
         DAO  2 vviiGGGiiGlstAyeLarrg.....Vtllekgd 30
                +++ G+G +Gl++A + a +g     + +le++ 
  EEA20051.1  8 IIVCGAGSAGLCAATFMASAGipaehIKILERNA 41
                89****************9999999******994 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.084
                 EEEEHHHHHHHSTTSTTTSEEEEETTEEEEEHHHHHHHHHHHH.HHTT-EEEESECEEEEEEEETCEEEEE...EECT.EEE.E....EEEEEEE--GG CS
         DAO 114 elldaeevrelepalpgllgalfypdtgqvdpakltaalaraa.ealGveilegtevtgleeedgkvwgve...rttp.gen.d....aadavVnaaGa 202
                 +l++ +++++  p      g  + p+  +++ a++   l++++  ++G e+ +g +v ++  +  k+   +   ++++ g++      +a++v  + Ga
  EEA20051.1  94 QLVRTRRTADTMP------GLSHHPH-VILNQARMNGMLLKKMhDEAGMEVEYGWNVSNVTVDF-KGDPDFpcvVVAKrGIEgPettmRARYVLGCDGA 184
                 4554444555554......3346777.8999999999999997577789999999999985533.2222233442223355432454545889999999 PP

                 GHH..HHHTT..CTT.TSEEEEEEEEEEEEEECCTHSTGSGCSEEEEEEEETTTTEEEEEET CS
         DAO 203 wsd..llgll..kel.dlpispvrgqvlvlkplseklvspaailpvpetdddgrgvyvtprk 259
                 +s+      l  k + d  + +v g + v+ p ++   +p+ i      ++ ++ + ++pr+
  EEA20051.1 185 HSTvrR--SLgyKMIgD-STDAVWGVMDVY-PQTN---FPD-IRKKATLHTKSGNLMIIPRE 238
                 997431..233333322.225555555555.4333...332.22222256666666666765 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 2.4
                 EESSSSTHHSTHHHHHHHH.HHHHHHHHHHHHHS CS
         DAO  44 lhsglrylpeaselarlsl.ealeelreleeelg 76 
                 l+ g+r +p+  +++rl+  +a+++ r++ ++ g
  EEA20051.1 422 LTVGMR-FPST-QVVRLCDaRAMQLVRAFPAD-G 452
                 445556.6665.77888876777887887776.3 PP

>> MCRA  MCRA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.1   5.7e-05      0.13       6      39 ..      10      42 ..       6      64 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 5.7e-05
                EE--SHHHHHHHHHHHHTT---GGGEEEE-SS-- CS
        MCRA  6 lvGsGiasLaaAvyLirdakvpgenihileelkv 39
                + G+G a+L aA+++   a++p+e+i+ile+++ 
  EEA20051.1 10 VCGAGSAGLCAATFMA-SAGIPAEHIKILERNAG 42
                67************85.799**********9864 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   1.4   7.5e-05      0.17       2      22 ..       8      28 ..       7      32 .. 0.93

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 7.5e-05
                   EEEE--SHHHHHHHHHHHHTT CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaG 22
                   +iV+G+G AGL+AA+ +a aG
     EEA20051.1  8 IIVCGAGSAGLCAATFMASAG 28
                   79****************999 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.1   0.00028      0.63       2      30 ..      11      42 ..      10      56 .. 0.88
   2 ?   -3.3   0.0       4.9   1.1e+04      41      53 ..     133     145 ..     117     148 .. 0.71
   3 ?   -1.9   0.0       1.8   4.1e+03      32      66 ..     546     590 ..     539     592 .. 0.65

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00028
                   E--SHHHHHHHHHHHCCTE...EEEEE-SSSS CS
  NAD_binding_8  2 vGaGlsGlvaAylLakagf...dvlllekrdr 30
                    GaG +Gl+aA ++a ag+   ++ +le++ +
     EEA20051.1 11 CGAGSAGLCAATFMASAGIpaeHIKILERNAG 42
                   6****************888788999998765 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 4.9
                    TTCEECTS---EE CS
  NAD_binding_8  41 pgvrvdygahifh 53 
                     g+ v+yg+++ +
     EEA20051.1 133 AGMEVEYGWNVSN 145
                    4688999998765 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 1.8
                    SGGG-EECE......TT....CEECTS---EEETTHHHHCHHHHC CS
  NAD_binding_8  32 GGraasyev......pg....vrvdygahifhgsgyypnvrrllr 66 
                    +G+ ++ye       +g    vr d+  +i+ +  +y+ ++r+++
     EEA20051.1 546 SGHGHTYETyqidktEGavviVRPDHYISIISSLIDYDTINRFFE 590
                    677777777666544337666666777777777666888888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (596 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       366  (0.0204139); expected 358.6 (0.02)
Passed bias filter:                      356  (0.0198561); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.44
# Mc/sec: 4085.68
//
Query:       EEA20052.1  [L=326]
Description: hypothetical protein PMAA_039190 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (326 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       700  (0.0390429); expected 358.6 (0.02)
Passed bias filter:                      338  (0.0188521); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.41
# Mc/sec: 2405.19
//
Query:       EEA20053.1  [L=533]
Description: amino acid permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.2e-63  214.0  54.4      4e-63  213.7  54.4    1.0  1  AA_permease_2  Amino acid permease
    7.7e-20   70.9  40.0      1e-19   70.6  40.0    1.0  1  AA_permease    Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  213.7  54.4   4.4e-67     4e-63       3     423 ..      56     501 ..      54     506 .. 0.88

  Alignments for each domain:
  == domain 1  score: 213.7 bits;  conditional E-value: 4.4e-67
  AA_permease_2   3 llsafalvigsvigsgifvkn...laasggpalilwvwiavligslavllvyaElssalprsgGiyvytkaaf....gkkvaflsawfnwfayvpv 91 
                     ls +al+++++++  +++++   ++++ggp++++w+++ ++ g la+++ +aE++s  p  g +y++t+ +      +++ ++ +w++ fa+  +
     EEA20053.1  56 SLSILALSVTLLASWEGLASTfsaSLLNGGPSSLVWGLLLSFTGTLAMAFSLAEMASICPIAGAQYHWTALFAptaiRPFITWMQGWATIFAWQSS 151
                    578888999999775555555555999*******************************************99755668****************** PP

  AA_permease_2  92 lasilsvaasyllnal...gpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfsslstetdtffp 184
                    ++si+ ++a+  ++++   +p+++ ++w++ l+++a++++ +++n+ gi+ +  +q ++gi+++++  +i++ ++li++ ++  ++     +t+++
     EEA20053.1 152 TTSIFLLVAKQVQGLIilnYPSYNATRWQSTLLMWAFTAFSFAVNVWGIRLLPLLQLFGGIFHVVF--FIALSVPLILLAPRSTPEF--VFKTVMS 243
                    *****9999988777544368*******************************************64..567778*****99999964..5556777 PP

  AA_permease_2 185 n.gwpgv....llgllivlwsfdGfesaanvseevkk..kdvpkaifigllivlvlyllvniaflgvvpddeianlsnlgsv.aalffeavggkvv 272
                    + gw  +      g+l+v+++f Gf++a+++seev++  + vp+ i+ +++i +vl +++ + +l+ ++d + a    +g + +a+f+ a+++  +
     EEA20053.1 244 EgGWENNgiswCIGMLTVTYCFLGFDGAVHMSEEVRNpaRVVPRIIVQSVVINGVLAFGFVLILLFFIGDVNAALDTASGFPsIAIFYTATNSEKA 339
                    76888533355779999*****************9988688******************************9987666666658********99** PP

  AA_permease_2 273 aiivvilialsllgaintavigssrvlealardgvlP..rffakvn.kfgspiraiiltaivslillllfllassaaynfllsvsslgliisylll 365
                    a++++ +i+ + l++ +++v+++sr+ +a+ardg+lP  +ff++++ +f+ p+ +i l++ v+++l+ l+ ++s++a+ ++l++s+++l+isyl++
     EEA20053.1 340 ATAMQCGITAIGLISSIGVVASVSRLTWAFARDGGLPfsKFFSQIDnRFHVPFHSIGLVCGVAVLLS-LINIGSTTALGAILALSTCSLYISYLIP 434
                    **********************************************9****************7776.5556679********************* PP

  AA_permease_2 366 iigalilrkkrphlkr....pgk......ilvaiigalfllfllvalffppkgpatqssliytiiltv 423
                    i+++++ r++    k     +         +v+i +++f  f++v++ fp+  p+t ++++y+  +++
     EEA20053.1 435 ITLLVFRRFDTSGTKVkwgpW-TmgpwvgLVVNIYSIVFGMFIIVFTPFPSMLPVTAENMNYSGPVFG 501
                    **********88664433541.245544579********************************55544 PP

>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.6  40.0   1.1e-23     1e-19      19     471 ..      77     520 ..      64     527 .. 0.78

  Alignments for each domain:
  == domain 1  score: 70.6 bits;  conditional E-value: 1.1e-23
  AA_permease  19 lgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgpelGfviGlnylfswitvlaleltaasiliqfwelvtdlpkawvt 116
                   +  l ++Gp +++ ++ll+++ +++++ sl+e+a++ p +g+ y++ + f   +   +i ++    w+t +a +  + si++  ++ v+ l+ + + 
   EEA20053.1  77 FSASLLNGGPSSLVWGLLLSFTGTLAMAFSLAEMASICPIAGAQYHWTALFAPTAIRPFITWM--QGWATIFAWQSSTTSIFLLVAKQVQGLIILNYP 172
                  5677889**************************************987776666666666666..556677777777777777777666666633333 PP

  AA_permease 117 ........gavflvvlliinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkgagfrflgdngsifknnlppgfakeeegafknfisvfv 206
                          +++++ ++++++++ + +  +   +l l+ +i  + f+i + ++l+  +p           + ++fk  +++g     e +  ++++++ 
   EEA20053.1 173 synatrwqSTLLMWAFTAFSFAVNVWGIRLLPLLQLFGGIFHVVFFIALSVPLILLAPRST--------PEFVFKTVMSEG---GWENNGISWCIGML 259
                  7777788988888888888888888888877788888888888888888555555554444........335566666666...22223479****** PP

  AA_permease 207 ivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasaaspfvifikesgvsvlaplinaviltaalssa 304
                  +v   f G+   + +++Ev++P++ +P+ i q v++ +++  +++l++ + +++ +  l ++s    + + if + +++  +a+ + ++i +  l s+
   EEA20053.1 260 TVTYCFLGFDGAVHMSEEVRNPARVVPRIIVQSVVINGVLAFGFVLILLFFIGDVNAALDTASGF--PSIAIFYTATNSEKAATAMQCGITAIGLISS 355
                  ***************************************99999999999999999888886665..5****************************** PP

  AA_permease 305 nsslysasRvlyslakdglaP...kvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliilsylrfRkalkyqgr 399
                  ++ ++s sR+ +++a+dg +P   ++ +  ++ +vP  +i l++ +++l+ l++  ++    +   +la+s+ +  i +l+ i+ ++ fR+ + ++g 
   EEA20053.1 356 IGVVASVSRLTWAFARDGGLPfskFFSQIDNRFHVPFHSIGLVCGVAVLLSLINIGSTT---ALGAILALSTCSLYISYLIPITLLV-FRR-FDTSGT 448
                  ***********************5555566788************99999988776666...8888888888888888877777666.665.578888 PP

  AA_permease 400 sieelgfka..allplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfliilvgvklhvk 471
                  +++  + ++  +++    i+ +++ ++i++++ +   l+   + ++++++  ++  + +ll++  +  +k+++k
   EEA20053.1 449 KVKWGPWTMgpWVGLVVNIYSIVFGMFIIVFTPFPSMLP--VTAENMNYSGPVFGGMAILLVIDWFARGKDRFK 520
                  777766666334555555555555555555555555555..677778888888888888888777777776666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (533 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       726  (0.0404931); expected 358.6 (0.02)
Passed bias filter:                      291  (0.0162307); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 3702.90
//
Query:       EEA20054.1  [L=525]
Description: developmental regulator flbA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.7e-28   97.8   0.2    4.1e-27   94.8   0.0    2.3  2  RGS       Regulator of G protein signaling domain
      6e-17   61.5   0.1    9.7e-16   57.6   0.0    2.7  3  DEP       Domain found in Dishevelled, Egl-10, and Pleckstrin


Domain annotation for each model (and alignments):
>> RGS  Regulator of G protein signaling domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0      0.12   1.1e+03      47      60 ..     105     118 ..      93     129 .. 0.62
   2 !   94.8   0.0   4.6e-31   4.1e-27       1     115 [.     355     493 ..     355     495 .. 0.96

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.12
                 HHHHHHHHHHHTST CS
         RGS  47 kkkakeIyneylap 60 
                 k++a++I++++++ 
  EEA20054.1 105 KEMARSIFQNFIQA 118
                 34455555555543 PP

  == domain 2  score: 94.8 bits;  conditional E-value: 4.6e-31
                 -HHHHHTSHHHHHHHHHHHHHTTCTHHHHHHHHHHHHHTS.............SHHHHHHHHHHHHHHHHTSTTSTTSSTS-HHHHHHHHHHHCSS... CS
         RGS   1 sleslledqpgrslFreFlesefseenlsFwlaveefkka.............keqeelkkkakeIyneylapsspkelnidkklreelekrleke... 83 
                 +l+++l+d+++r lFre+l  +f+eenl+F+++v e+  +             ++ ++ ++ ++ +yn +lap+sp+elnid++lr+++ + ++     
  EEA20054.1 355 RLQYILNDPSLRLLFREYLAASFCEENLAFYQDVTEYVDNyrnskmsdelkdyHKLQDYIAGVFGLYNSFLAPGSPCELNIDHALRNRISSEMTGLsgd 453
                 6899**********************************************998888889999********************************999** PP

                 ........STTTTTTHHHHHHHHHHHHHHHHHHHHTSHHH CS
         RGS  84 ........qpsrklfeeaqeevfellekdsypkFlksely 115
                          +  +l + aq  +f+l+++ds+pkF++ + y
  EEA20054.1 454 ektvarnlDEVVNLCQLAQVTIFKLMASDSVPKFCRHPRY 493
                 ************************************9988 PP

>> DEP  Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.0      0.23   2.1e+03       2      24 ..      47      69 ..      46      74 .. 0.85
   2 ?   -0.5   0.0      0.14   1.3e+03      33      55 ..     102     124 ..      93     129 .. 0.82
   3 !   57.6   0.0   1.1e-19   9.7e-16       4      71 ..     231     308 ..     229     309 .. 0.97

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.23
                S-SCEEECTTEEESSE-HHHHHH CS
         DEP  2 vklkdrrkhlktypncftGseav 24
                ++l+ rr++++++  +ft +ea 
  EEA20054.1 47 LELSARRVRFTKVDFTFTVEEAL 69
                67899************988875 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.14
                 SSSHHHHHHHHHHHHHCTSCECS CS
         DEP  33 iedreeAvalgqlLldqgliehv 55 
                 ++  e A ++ q +++ +++e++
  EEA20054.1 102 TMAKEMARSIFQNFIQARFLEPL 124
                 556789999********999987 PP

  == domain 3  score: 57.6 bits;  conditional E-value: 1.1e-19
                 SCEEECTTEEESSE-HHHHHHHHHHHHTSSSSHHHHHHHHHHHHHCTSCECSSSSHCC..........--SSSSS-EE CS
         DEP   4 lkdrrkhlktypncftGseavdWLldnldiedreeAvalgqlLldqgliehvedkhqe..........FrdskqafYq 71 
                 ++d r+++++y+++ftG+ a+ WL+d+++++d +e+ +++++++++gli+ + +++++          F+++ qa+Y 
  EEA20054.1 231 MQDIRVNGRKYQYAFTGKSAINWLMDCCTTIDERETYSVCEQFIEHGLITAIVEDKSYiaekdqaalnFQPTRQAIYA 308
                 899**************************************************************************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (525 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       635  (0.0354175); expected 358.6 (0.02)
Passed bias filter:                      537  (0.0299515); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.43
# Mc/sec: 3706.60
//
Query:       EEA20055.1  [L=400]
Description: NAD binding Rossmann fold oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.4e-25   88.3   0.0      1e-24   87.6   0.0    1.3  1  GFO_IDH_MocA    Oxidoreductase family, NAD-binding Rossmann f
     0.0043   17.5   0.0     0.0086   16.5   0.0    1.4  1  Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domai
  ------ inclusion threshold ------
       0.04   14.6   0.0       0.07   13.8   0.0    1.3  1  NAD_binding_3   Homoserine dehydrogenase, NAD binding domain


Domain annotation for each model (and alignments):
>> GFO_IDH_MocA  Oxidoreductase family, NAD-binding Rossmann fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.6   0.0   1.7e-28     1e-24       9     116 ..      33     146 ..      28     150 .. 0.93

  Alignments for each domain:
  == domain 1  score: 87.6 bits;  conditional E-value: 1.7e-28
                   SHHHHHHHHHHHHTTTTE.....EEEEEECSSHHHHHHHHHHTTHE.EESSHHHHHTCTTESEEEE-S-GGGHHHHHHHHHHTT-EEEEESSS-SSH CS
  GFO_IDH_MocA   9 Gkigskhlrplnesqrle.....evvalldpdaeraeavaesfgve.aysdleelladpeidavivatpngtheelakaaleagkhvllEKPlattv 99 
                   G i + h++p    +++e      + a+ ++d e+a++ a++++++ ay ++++ll+d++id++++ tpng h+e a +al+agkhvl+EKP++ + 
    EEA20055.1  33 GVISTAHINPAAIIRPTEthpdvILHAIASRDLESAKQTARKYHFKkAYGSYQDLLDDSDIDIIYISTPNGMHYEWASKALRAGKHVLCEKPFTSNA 129
                   6788888888888888888888899************************************************************************ PP

                   HHHHHHHHHHHHHTS-E CS
  GFO_IDH_MocA 100 eeakelvelaekkgklv 116
                   eea +l+ela++kg ++
    EEA20055.1 130 EEAHRLIELAKEKGLVC 146
                   *************9876 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   1.4e-06    0.0086      17      93 ..      47     119 ..      43     121 .. 0.75

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 1.4e-06
                     HHHHCTSSEEEEEEEESTTTTTSBHHHHSGGGTTTECEBEEEGGGGGCTT-SEEEE-SCHHHHHHHHHHHHHTTSEE CS
  Semialdhyde_dh  17 rlLeehpevelvvllsssrsaGkklaeavkaleegkdlkvedvdeeelkevdivflalpagvskelapklaeagvkv 93 
                     r  e+hp+v l++++s++ +  k+ a++++   +++  +++d    + +++di+  ++p+g++ e+a k++ ag +v
      EEA20055.1  47 RPTETHPDVILHAIASRDLESAKQTARKYH--FKKAYGSYQD--LLDDSDIDIIYISTPNGMHYEWASKALRAGKHV 119
                     55578**********999955555555544..2344445555..4455799***********************987 PP

>> NAD_binding_3  Homoserine dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   1.2e-05      0.07      21     111 ..      54     143 ..      41     146 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.2e-05
                    EEEEEEEEESSEEE-TTHHHHHT--CB---HHHHHHHHS-EEEEE-S--HHHHTTHHHHHHTTEEEE-S--CGGG-HHHHHHHTSSSTTS- CS
  NAD_binding_3  21 elelvavadrdsllskdrkallasealtldlddliahldpdvvVEcasseavaelvlkaLkagkdvvtankgaladealyeeLreaaeang 111
                    ++ l a+a rd + +k+++++   ++ + + +dl+++ d+d++   ++     e + kaL+agk+v+ + k   ++ +  ++L+e+a+++g
     EEA20055.1  54 DVILHAIASRDLESAKQTARKYHFKKAYGSYQDLLDDSDIDIIYISTPNGMHYEWASKALRAGKHVL-CEKPFTSNAEEAHRLIELAKEKG 143
                    56688999999666777999*********************************************98.56666668899999999999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (400 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       515  (0.0287244); expected 358.6 (0.02)
Passed bias filter:                      462  (0.0257683); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.40
# Mc/sec: 3014.30
//
Query:       EEA20056.1  [L=351]
Description: cell wall organization protein/glutathione transferase (Gto3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-19   69.5   0.0    4.9e-19   68.4   0.0    1.6  1  GST_N_2   Glutathione S-transferase, N-terminal domain
    2.7e-11   43.3   0.0    7.6e-11   41.9   0.0    1.8  1  GST_C_2   Glutathione S-transferase, C-terminal domain
     0.0041   17.5   0.0        5.4    7.5   0.0    2.5  2  GST_N_3   Glutathione S-transferase, N-terminal domain
     0.0044   17.2   0.0     0.0097   16.1   0.0    1.6  1  GST_C_3   Glutathione S-transferase, C-terminal domain
  ------ inclusion threshold ------
      0.062   13.5   0.0       0.15   12.3   0.0    1.6  1  GST_C     Glutathione S-transferase, C-terminal domain


Domain annotation for each model (and alignments):
>> GST_N_2  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.4   0.0   1.4e-22   4.9e-19       1      69 [.      43     147 ..      43     148 .. 0.92

  Alignments for each domain:
  == domain 1  score: 68.4 bits;  conditional E-value: 1.4e-22
                 S-HHHHHHHHHHHHCT--EEEEEE..H...-TTSHHHHH.................................HHHCTTTSSSEEE-CTTE..EEESHHH CS
     GST_N_2   1 aCPwahRvlialalkglediisvv..vlepkgfekseef.................................prlnprgtVPvLwdkdgq..vineSse 62 
                 +CP+ahR+ ++++ kgl+++i+v+   + pkg++k+ +                                   ++++r++VP+Lwdk+++  v+neS+e
  EEA20056.1  43 FCPFAHRANLVRHIKGLQSAIDVSivRAYPKGDSKG-WPgwkfpaheqeyegatvdklfgseylhgvyfkddEDYKGRYSVPLLWDKKTNriVNNESAE 140
                 8**********************6558899999987.7789999999999************************************966679******* PP

                 HHHHHHH CS
     GST_N_2  63 Ilrylet 69 
                 Ilr+l t
  EEA20056.1 141 ILRWLPT 147
                 *****87 PP

>> GST_C_2  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.9   0.0   2.1e-14   7.6e-11       6      67 ..     202     271 ..     178     273 .. 0.89

  Alignments for each domain:
  == domain 1  score: 41.9 bits;  conditional E-value: 2.1e-14
                 HHHHHCCHCHHHCTTT---SS...CTTCS--HHHHHHHHHHHHHHHHHHS-......---TT-HHHHHHH CS
     GST_C_2   6 raleqldaaldaleahLadsp..flfGdqptlaDialapflvrlraagpgf......direaypnlraWl 67 
                  a+  ++ al +le+++ ++   +++G+++t  Di+l+++l+r+++++ ++      +ir++yp l+aWl
  EEA20056.1 202 KAVIPVFGALNVLEKLIYKKGgpYVLGAHLTELDIRLYATLIRFDTVYVQHfkcnlgTIRHDYPVLNAWL 271
                 466778899999***77766669************************99999*****************8 PP

>> GST_N_3  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.3   0.0    0.0017       6.1       1      25 [.      38      62 ..      38      81 .. 0.78
   2 !    7.5   0.0    0.0015       5.4      41      74 ..     116     152 ..     105     153 .. 0.78

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0017
                EES-TTSHHHHHHHHHHHHHT--EE CS
     GST_N_3  1 LygfpaSpyarrvrlaLnekglpve 25
                Ly   ++p+a r+ l+ + kgl+ +
  EEA20056.1 38 LYIGLFCPFAHRANLVRHIKGLQSA 62
                666789****************733 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0015
                 H-TT--SSEEETT..S-.EEESHHHHHHHHHHHH-GG CS
     GST_N_3  41 knplgkvPvLedd..ge.altdSlaIidyLeelypgp 74 
                 + +++ vP L d   ++ +  +S++I+++L ++++g 
  EEA20056.1 116 YKGRYSVPLLWDKktNRiVNNESAEILRWLPTAFNGT 152
                 558999****66533554667*********9999876 PP

>> GST_C_3  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0   2.7e-06    0.0097      20      83 ..     196     271 ..     175     283 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 2.7e-06
                 HHHHHHHHHHHCH..HHHHHHHHHCHGTSSSSTTS--HHHHHHHHHHHHHHHH..........TCC.CC-HHHHHHH CS
     GST_C_3  20 kkkefleerlpkf..lkyfekvlkkkgggylvgdklTyADlalfqvldgleea..........eal.kkfpklkaly 83 
                  ++++ +  +p f  l+++ek++ kkgg+y++g +lT  D+ l++ l  +  +               ++p l a+ 
  EEA20056.1 196 TQEDYDKAVIPVFgaLNVLEKLIYKKGGPYVLGAHLTELDIRLYATLIRFDTVyvqhfkcnlgT-IrHDYPVLNAWL 271
                 5566666666665558999**99988888****************9988887777666554422.246777777665 PP

>> GST_C  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   4.1e-05      0.15      18      89 ..     194     274 ..     153     276 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 4.1e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHHH..TSSSSSTTSSCHHHHHHHHHHH.....HHHHHTTTTT..TTTSHHHHHHHHHH CS
       GST_C  18 ekkeelvdealekvaevlsaleeelk..kqdylvGdkltlADialvpiln.....wlqrlglafg..qekfpnlkawleri 89 
                 ++ +e++d+a   v+ +l++le+ +   +  y+ G +lt  Di l++ l      ++q+++ ++g  + ++p l awl+++
  EEA20056.1 194 ATTQEDYDKAVIPVFGALNVLEKLIYkkGGPYVLGAHLTELDIRLYATLIrfdtvYVQHFKCNLGtiRHDYPVLNAWLTHL 274
                 5668899999999999*******99877889************8888777688999999999999*************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (351 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       314  (0.0175135); expected 358.6 (0.02)
Passed bias filter:                      280  (0.0156172); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2648.73
//
Query:       EEA20057.1  [L=324]
Description: cell wall organization protein/glutathione transferase (Gto3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.8e-19   69.8   0.0    4.1e-19   68.6   0.0    1.7  1  GST_N_2   Glutathione S-transferase, N-terminal domain
    2.2e-11   43.6   0.0    6.5e-11   42.1   0.0    1.8  1  GST_C_2   Glutathione S-transferase, C-terminal domain
     0.0037   17.4   0.0     0.0082   16.3   0.0    1.6  1  GST_C_3   Glutathione S-transferase, C-terminal domain
     0.0089   16.4   0.0        4.8    7.7   0.0    2.6  2  GST_N_3   Glutathione S-transferase, N-terminal domain
  ------ inclusion threshold ------
      0.051   13.8   0.0       0.13   12.5   0.0    1.7  1  GST_C     Glutathione S-transferase, C-terminal domain


Domain annotation for each model (and alignments):
>> GST_N_2  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.6   0.0   1.2e-22   4.1e-19       1      69 [.      16     120 ..      16     121 .. 0.92

  Alignments for each domain:
  == domain 1  score: 68.6 bits;  conditional E-value: 1.2e-22
                 S-HHHHHHHHHHHHCT--EEEEEE..H...-TTSHHHHH.................................HHHCTTTSSSEEE-CTTE..EEESHHH CS
     GST_N_2   1 aCPwahRvlialalkglediisvv..vlepkgfekseef.................................prlnprgtVPvLwdkdgq..vineSse 62 
                 +CP+ahR+ ++++ kgl+++i+v+   + pkg++k+ +                                   ++++r++VP+Lwdk+++  v+neS+e
  EEA20057.1  16 FCPFAHRANLVRHIKGLQSAIDVSivRAYPKGDSKG-WPgwkfpaheqeyegatvdklfgseylhgvyfkddEDYKGRYSVPLLWDKKTNriVNNESAE 113
                 8**********************6558899999987.7789999999999************************************966679******* PP

                 HHHHHHH CS
     GST_N_2  63 Ilrylet 69 
                 Ilr+l t
  EEA20057.1 114 ILRWLPT 120
                 *****87 PP

>> GST_C_2  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.1   0.0   1.8e-14   6.5e-11       6      67 ..     175     244 ..     151     246 .. 0.89

  Alignments for each domain:
  == domain 1  score: 42.1 bits;  conditional E-value: 1.8e-14
                 HHHHHCCHCHHHCTTT---SS...CTTCS--HHHHHHHHHHHHHHHHHHS-......---TT-HHHHHHH CS
     GST_C_2   6 raleqldaaldaleahLadsp..flfGdqptlaDialapflvrlraagpgf......direaypnlraWl 67 
                  a+  ++ al +le+++ ++   +++G+++t  Di+l+++l+r+++++ ++      +ir++yp l+aWl
  EEA20057.1 175 KAVIPVFGALNVLEKLIYKKGgpYVLGAHLTELDIRLYATLIRFDTVYVQHfkcnlgTIRHDYPVLNAWL 244
                 466778899999***77766669************************99999*****************8 PP

>> GST_C_3  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   2.3e-06    0.0082      20      83 ..     169     244 ..     147     256 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 2.3e-06
                 HHHHHHHHHHHCH..HHHHHHHHHCHGTSSSSTTS--HHHHHHHHHHHHHHHH..........TCC.CC-HHHHHHH CS
     GST_C_3  20 kkkefleerlpkf..lkyfekvlkkkgggylvgdklTyADlalfqvldgleea..........eal.kkfpklkaly 83 
                  ++++ +  +p f  l+++ek++ kkgg+y++g +lT  D+ l++ l  +  +               ++p l a+ 
  EEA20057.1 169 TQEDYDKAVIPVFgaLNVLEKLIYKKGGPYVLGAHLTELDIRLYATLIRFDTVyvqhfkcnlgT-IrHDYPVLNAWL 244
                 5566666666765558999**99988888****************9988887777666554422.246777777665 PP

>> GST_N_3  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.0   0.0    0.0045        16       6      25 ..      16      35 ..      14      54 .. 0.79
   2 !    7.7   0.0    0.0013       4.8      41      74 ..      89     125 ..      78     126 .. 0.78

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.0045
                TSHHHHHHHHHHHHHT--EE CS
     GST_N_3  6 aSpyarrvrlaLnekglpve 25
                ++p+a r+ l+ + kgl+ +
  EEA20057.1 16 FCPFAHRANLVRHIKGLQSA 35
                8****************733 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0013
                 H-TT--SSEEETT..S-.EEESHHHHHHHHHHHH-GG CS
     GST_N_3  41 knplgkvPvLedd..ge.altdSlaIidyLeelypgp 74 
                 + +++ vP L d   ++ +  +S++I+++L ++++g 
  EEA20057.1  89 YKGRYSVPLLWDKktNRiVNNESAEILRWLPTAFNGT 125
                 568999****66533554667*********9999876 PP

>> GST_C  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   3.5e-05      0.13      18      89 ..     167     247 ..     126     249 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 3.5e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHHH..TSSSSSTTSSCHHHHHHHHHHH.....HHHHHTTTTT..TTTSHHHHHHHHHH CS
       GST_C  18 ekkeelvdealekvaevlsaleeelk..kqdylvGdkltlADialvpiln.....wlqrlglafg..qekfpnlkawleri 89 
                 ++ +e++d+a   v+ +l++le+ +   +  y+ G +lt  Di l++ l      ++q+++ ++g  + ++p l awl+++
  EEA20057.1 167 ATTQEDYDKAVIPVFGALNVLEKLIYkkGGPYVLGAHLTELDIRLYATLIrfdtvYVQHFKCNLGtiRHDYPVLNAWLTHL 247
                 5668899999999999*******99877889************8888777688999999999999*************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (324 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       446  (0.0248759); expected 358.6 (0.02)
Passed bias filter:                      395  (0.0220313); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2251.00
//
Query:       EEA20058.1  [L=342]
Description: aldo/keto reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.4e-70  237.1   0.0    2.7e-70  236.9   0.0    1.0  1  Aldo_ket_red  Aldo/keto reductase family


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  236.9   0.0   1.5e-74   2.7e-70       1     290 [.      17     313 ..      17     317 .. 0.95

  Alignments for each domain:
  == domain 1  score: 236.9 bits;  conditional E-value: 1.5e-74
                   .EEEE-SSS-ST...TS-HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH-TTTGGG-EEEEEE....--SSSTTSSSS-HHHHHHHHH CS
  Aldo_ket_red   1 elglGtwqlgsk..eeiskeealellrraleaGinffDtAevYgkgqseellGealkksrkkreeviiatKv....dlrdaeiksglskeniresle 91 
                   e+g+G++++g+    + ++ee  +ll++a   G +f+DtA++Y    se+++G ++k++++kr+++++atK     d  ++++  + ++e i e++e
    EEA20058.1  17 EIGFGLMSIGGVygAAPNDEERSALLDHAHTIGERFWDTADIY--ADSEDVVGLWVKQNPEKRKDIFLATKFgiqfDPATYTQTLHSNPEYIKEACE 111
                   69*********9*9999**************************..*****************************7777777777777788******* PP

                   HHHHHHT-S-EEEEEE-S--TTS-.HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHHHHTTT--EEEEE-B-BTT...-HHHHTTHHHHHHHTT-E CS
  Aldo_ket_red  92 eslkrLgtdyvDllllHrpdpslpsieevldaleelvkeGkiraiGvSnfsveqlekakkkkkvkivavqveynll...releeegllelckkkgvp 185
                   +slkrL+t  +Dl+++Hr+d ++p ie++++a++el+ +Gkir++G+S++s+  l++a  +++++i+avq ey++     e+ + gl+++++++g++
    EEA20058.1 112 RSLKRLNTGWIDLYYCHRVDGKTP-IEKTVEAMVELKNQGKIRHLGLSEVSASTLRRA--HAVHPIAAVQLEYSPIaiePEDPKIGLIQTARELGIA 205
                   ************************.*******************************99..****************998889999************ PP

                   EEEBSTTGGGTTGTTTSS---SSSCCC-------...TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTSTT-SEEEE--SSHHHHHHHHGGGG- CS
  Aldo_ket_red 186 liaysplggGlltgkyqseedkedkeprkdlkrd...ertsknldaaeelselakehgvslaqlalryalsqpavgivipgasnieqlednldalel 279
                   ++aysp+g+G ++g y++ e+++  +p   +  +   e++++ ld++ +++++ak++g++  qla++++ls+   ++vipg+++i+ le+nl+ +++
    EEA20058.1 206 IVAYSPMGRGVISGGYKTAEEVHAIDPFLAMLPRfskENYPRILDMITAFEQVAKSKGCTTGQLAMAWVLSRGEDVFVIPGTRKIKYLEENLATQHI 302
                   ***********************999988887779************************************************************** PP

                   ---HHHHHHHH CS
  Aldo_ket_red 280 klseeevaeld 290
                   +l++ e ++l 
    EEA20058.1 303 TLTSAEEKTLS 313
                   99998877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       332  (0.0185175); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2345.16
//
Query:       EEA20059.1  [L=563]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.7e-09   36.6   7.4    6.8e-09   35.7   7.4    1.4  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.7   7.4   3.8e-13   6.8e-09       2      35 ..       9      42 ..       8      44 .. 0.93

  Alignments for each domain:
  == domain 1  score: 35.7 bits;  conditional E-value: 3.8e-13
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCT CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfyse 35
                +C +C+k++vKCd++kP+C+ C++l+l C  y+ 
  EEA20059.1  9 GCVTCKKRRVKCDEEKPECQTCQRLGLLCGGYKP 42
                6****************************98875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (563 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       499  (0.027832); expected 358.6 (0.02)
Passed bias filter:                      385  (0.0214736); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.39
# Mc/sec: 4363.15
//
Query:       EEA20060.1  [L=546]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-37  128.9  51.4      2e-37  128.9  51.4    2.3  2  MFS_1     Major Facilitator Superfamily
    3.8e-15   55.3  19.1      5e-15   54.9  19.1    1.1  1  TRI12     Fungal trichothecene efflux pump (TRI12)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  128.9  51.4   2.3e-41     2e-37       2     352 ..      50     451 ..      49     452 .. 0.82
   2 ?    0.4   0.1     0.027   2.4e+02     144     170 ..     500     527 ..     495     543 .. 0.59

  Alignments for each domain:
  == domain 1  score: 128.9 bits;  conditional E-value: 2.3e-41
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgag 100
                 ++a+fl+al+ +i+g+a+p  ++++++     +++ +++y+ +++ ++  +G +   f  ++++l+++++f lg+l++ +a+++ +l+v+r+++Glg++
  EEA20060.1  50 IIAVFLIALDQTIVGTAIP-KITDEFH-GLNDVSWYAAAYFMTFGSSQTSAGKVYKYFNLKWTFLISMFIFELGSLICGVAPNSNALIVGRAISGLGGA 146
                 689****************.*******.**********************************************88888668888************** PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee........... 188
                 +l  +g ++++  + + +r++++g+++++++++a+lgpl+gg++++ ++Wr++fyi+ +++ la++ +++++  ++ + ++  + +e+           
  EEA20060.1 147 GLSVGGTSILSLTVLPAKRPMMMGVIGMTYAVAAVLGPLIGGAFTDRISWRWCFYINLPIGGLAAISIFFFFHLPAAAVPPRITLTEKllhidpvgiil 245
                 ******************************************************************555666666666666666666668********* PP

       MFS_1 189 .....................kgtgpaplvp..................awkallkdpvl.....w...illialllfffgfsg...lltllplylqev 237
                                      +        +                  aw++ l    +     w   +l +++ + ff++ +   ll++lp+y+q+ 
  EEA20060.1 246 tmggitcfilalqyggnshpwN--------SnivigllvgfglmvialvAWEIWLGEYAMmlprlWkhrSLSTTASYQFFFMGSyiaLLYYLPIYFQSI 336
                 *************666555550........444445555555555555644444444433333335776333333333333333357************ PP

       MFS_1 238 lglsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllll.vlvliGfglgfvfpsllalasdlappeeag 335
                 lg s ++ +g+   ll l++a++al +g+++  +gr  + ++++++l+++a+gl+++  + +++  ++   +++G+ +++++   l++a+  a p+   
  EEA20060.1 337 LGAS-AIRSGVNNLLLVLAAAVFALAGGAVVIMTGRPQQVMFIGSILSTVAIGLIYTLDIGTSTPKWVgYQFFVGCSMAVAMMHGLSIAQAAADPKDLS 434
                 ****.55555555555555555578889988889999999999999999999999999995555555537788999999999999********99***9 PP

       MFS_1 336 tasglfntagslggalg 352
                 ++++   +++++gga++
  EEA20060.1 435 AVTANLLFFQTVGGAFS 451
                 9999999***9*99986 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.027
       MFS_1 144 la.sslgWravfyilaivsllafvlfll 170
                 l+   +g   +f+++ +++  a+++ l+
  EEA20060.1 500 LLaYMVGIKTAFVVAIAFCGTACLCSLA 527
                 3335667777777777777777775333 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.9  19.1   5.6e-19     5e-15       6     369 ..       8     367 ..       2     467 .. 0.70

  Alignments for each domain:
  == domain 1  score: 54.9 bits;  conditional E-value: 5.6e-19
       TRI12   6 hekgldlesqpddrlrakalatsadelpegyyrsprvvasfaafslnvvatyfvlqa.sasalpnilqdvgqsensslfstlwttgqavsilvmgrltd 103
                 + +g+  +s   d +r k  +   + l +  y     +  +a++s+  v    + q+   +a+p+i ++    ++ s +++ + +    s    g++  
  EEA20060.1   8 PREGVATNSSKADAFRDKGAT---KPLDDDDYPRGLTLVVLAGVSIIAVFLIALDQTiVGTAIPKITDEFHGLNDVSWYAAAYFMTFGSSQTSAGKVYK 103
                 567777888888888877533...44556666555566678888765555444445415789************************************* PP

       TRI12 104 rfgrr.pfvilthilglvgaivgctatkfntllaamtl..lgvaa.gpagasplfvgelmsnktkflgllivsipvvvtsglspylgqrlaiqgswrwi 198
                  f  +  f+i   i+ l   i g  a + n+l+   ++  lg a     g+s l +  l +++  ++g++ ++  v ++  l+p +g  ++ + swrw 
  EEA20060.1 104 YFNLKwTFLISMFIFELGSLICG-VAPNSNALIVGRAIsgLGGAGlSVGGTSILSLTVLPAKRPMMMGVIGMTYAVAAV--LGPLIGGAFTDRISWRWC 199
                 **966278888888877555555.5667788887555511444441456788888999999999999988777665544..79**************** PP

       TRI12 199 fyiyiitsaiavllivvwyyppsfaqlhgkkvrkreelakldwigiilvivgvslfllgvswggkpnspwnsakviglissglgslvv.falyevygkp 296
                 fyi + +  +a + i  +++ p+ a     +++  e+l ++d +giil + g++ f+l + +gg+   pwns  vigl+  g g +v+ +  +e++   
  EEA20060.1 200 FYINLPIGGLAAISIFFFFHLPAAAV--PPRITLTEKLLHIDPVGIILTMGGITCFILALQYGGNS-HPWNSNIVIGLLV-GFGLMVIaLVAWEIWL-G 293
                 **********************8764..6789999*****************************85.7*********996.7787776244578775.5 PP

       TRI12 297 vrpivppalfkdtrgfvcillissimgamnlslviiypqqvvnifgssl.kn.weetawmsatasfgtgagvvvl 369
                 +  ++ p l+k              mg+  ++l    p     i+g+s  +   ++   + a+a f    g vv+
  EEA20060.1 294 EYAMMLPRLWKHRSLSTTASYQFFFMGSY-IALLYYLPIYFQSILGASAiRSgVNNLLLVLAAAVFALAGGAVVI 367
                 67788889999866666666666778774.566666677777777766413314455556677777655554333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (546 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       633  (0.0353059); expected 358.6 (0.02)
Passed bias filter:                      244  (0.0136092); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.26s 00:00:00.86 Elapsed: 00:00:00.44
# Mc/sec: 3711.12
//
Query:       EEA20061.1  [L=536]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.1e-09   35.5  10.9    1.4e-08   34.7  10.9    1.3  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
    3.2e-07   29.5   0.5    4.6e-07   29.0   0.5    1.2  1  Fungal_trans_2  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.7  10.9   1.6e-12   1.4e-08       2      34 ..      15      47 ..      14      50 .. 0.93

  Alignments for each domain:
  == domain 1  score: 34.7 bits;  conditional E-value: 1.6e-12
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfys 34
                +C +C ++K+KCd+ kP C++C+k +l+C+ ys
  EEA20061.1 15 PCLTCQRRKIKCDRVKPDCQRCQKAGLQCEGYS 47
                8*****************************887 PP

>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.0   0.5   5.1e-11   4.6e-07       4     135 ..     122     253 ..     104     301 .. 0.74

  Alignments for each domain:
  == domain 1  score: 29.0 bits;  conditional E-value: 5.1e-11
  Fungal_trans_2   4 dyyldnvapllspvpessnpfrkvllplalsnk.....................allhallalsafhlqskgpkdslereakrykslalkelqea 77 
                     +                  +f++ +lp  +++                       l  al al+ ++    +++    +e++r+++ +l++++  
      EEA20061.1 122 S------------------YFLERYLPASMTSHrkfitpsswvrslpsllgrweVLDTALSALCLAYIGDVHQNYVHLHESQRLYNNVLQRISSM 198
                     4..................444555555554444555555555555555555536666666666666633333333689**************99 PP

  Fungal_trans_2  78 laelsstlsrnekykdiLaaiLllcsieissgdvsd...wrvhLeaatsliksrggskass 135
                     + +  +  +     + +L++++++ ++e ++++ ++   w  h ++a++l++ rg++  + 
      EEA20061.1 199 SLDSLKSAN-----EGVLTTTMIMAMYELFHSTYGRlqgWMFHVKGARRLLELRGPP-TKE 253
                     999999999.....9******************777788******************.222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (536 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       642  (0.0358079); expected 358.6 (0.02)
Passed bias filter:                      510  (0.0284455); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.29s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 3582.33
//
Query:       EEA20062.1  [L=343]
Description: quinone oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-13   51.3   0.0      2e-13   50.4   0.0    1.4  1  ADH_zinc_N    Zinc-binding dehydrogenase
      1e-10   41.4   0.0      2e-10   40.5   0.0    1.5  1  ADH_N         Alcohol dehydrogenase GroES-like domain
     0.0002   21.2   0.0    0.00045   20.1   0.0    1.5  1  ADH_N_2       N-terminal domain of oxidoreductase
     0.0002   22.4   0.0    0.00038   21.5   0.0    1.6  1  ADH_zinc_N_2  Zinc-binding dehydrogenase


Domain annotation for each model (and alignments):
>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.4   0.0   4.5e-17     2e-13       2      80 ..     172     247 ..     171     263 .. 0.86

  Alignments for each domain:
  == domain 1  score: 50.4 bits;  conditional E-value: 4.5e-17
                 HHHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTESEEEETTTC.HHHHHHHHHTTTSSEEEEEESSCSHHHHHHHHHCEE CS
  ADH_zinc_N   2 vGlaavqlAkalGaeviavdsseeklelakklGadevinykea.dlverikeltggegvdvvfecvGsgatleaalkllk 80 
                 vG++a+qlA a+G ev a++ss++  e++k+lGa +v++y ++ d+ ++i +    ++ d+v++c+G  ++  +++++l+
  EEA20062.1 172 VGSCAIQLAIAAGLEVAATASSKN-HEYVKSLGARHVFDY-NDpDVIKDITAVL--QPGDLVYDCIGGDQVRATCTEILQ 247
                 9*****************999996.7**************.6568888888888..699********6666666666665 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.5   0.0   4.5e-14     2e-10       2      62 ..      33      92 ..      32     114 .. 0.93

  Alignments for each domain:
  == domain 1  score: 40.5 bits;  conditional E-value: 4.5e-14
                TEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS--TT-EEEE- CS
       ADH_N  2 gevlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkklkvGdrVvve 62
                +ev+ikv++++++  D+ + ++ + le ++p++lG +++G+v+++g++v++++vG+rV+ +
  EEA20062.1 33 NEVVIKVAYTAMNPVDVVMQEN-APLELPYPFVLGVDLSGTVVALGSGVTRFQVGQRVTGH 92
                89***************99998.8**********************************865 PP

>> ADH_N_2  N-terminal domain of oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   0.0     1e-07   0.00045      18      92 ..      20      93 ..      12     104 .. 0.90

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 1e-07
     ADH_N_2 18 feleeeelpelkdGevlvralylSvDPymRgrmndaksyve.pvelgdvmrggavgeVveSknpdfkvGdlVvgll 92
                f++   + p++++ ev++++ y ++ P   ++ ++a   ++ p+ lg  + g++v+  + S   +f+vG+ V+g++
  EEA20062.1 20 FKIGPGPAPNPAENEVVIKVAYTAMNPVDVVMQENAPLELPyPFVLGVDLSGTVVA--LGSGVTRFQVGQRVTGHC 93
                77888899********************99888888777777*************9..79************9986 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.0   8.6e-08   0.00038       1      53 [.     202     258 ..     202     337 .. 0.74

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 8.6e-08
                   TT-SEEEETTSTTHH....HHH-TT-EEEEEES-HHHHH.HHHHHHE..EEEEEEEE-- CS
  ADH_zinc_N_2   1 lGAdevidyrtedfe....aatggegvDvvldtvggealleaslkvl..pggGrlvsig 53 
                   lGA +v+dy ++d+     a+++++  D+v+d++gg++  + + ++l   ggG+l ++ 
    EEA20062.1 202 LGARHVFDYNDPDVIkditAVLQPG--DLVYDCIGGDQVRATCTEILqqIGGGTLPTVR 258
                   8**************9886666555..************77777999865667776654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (343 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       293  (0.0163422); expected 358.6 (0.02)
Passed bias filter:                      274  (0.0152825); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 2259.90
//
Query:       EEA20063.1  [L=514]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.3e-62  208.0  38.8    7.8e-32  110.6  12.4    2.6  2  Chromate_transp  Chromate transporter
     0.0026   18.2   1.4     0.0085   16.5   1.4    2.0  1  DUF5533          Family of unknown function (DUF5533)


Domain annotation for each model (and alignments):
>> Chromate_transp  Chromate transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.6  12.4   8.7e-36   7.8e-32       3     143 ..      82     239 ..      80     315 .. 0.86
   2 !  102.9  18.4   2.1e-33   1.9e-29       3     156 ..     324     509 ..     322     510 .. 0.85

  Alignments for each domain:
  == domain 1  score: 110.6 bits;  conditional E-value: 8.7e-36
  Chromate_transp   3 lfl.fflkiGllifGGgyavipllreevverkgwlteeefldglalaqalPGPiavnlatfvGylilgvlGaliatlgfflPsfllilllapll 95 
                      lf+ ff+++Gl+++ G++a+i+l++e++v + +w+t ++f+ ++++ q+lPGP a++l++f+G+l +g lG+++a+++f+lP+f+l++l+++l+
       EEA20063.1  82 LFWfFFYNFGLFAWAGPVAQIALIKEKLVVQDKWITVARFQRVFSVYQVLPGPEATELCMFFGCLSAGKLGGFVAGIAFVLPGFILMVLASYLY 175
                      555167899*********************999********************************66*************************** PP

  Chromate_transp  96 eklrk.nplvkaaleglnaavvglilaaalslakk...............iallaflllllfkv 143
                      + l   n++++a++++++++v+++il a+  +a +               i++l+++l   +++
       EEA20063.1 176 SLLGMeNKYFNASFRAVQPVVAAMILRATHIIADHsvldhktrqikpilvIIALCTALNSALHI 239
                      **9668***********************97766677778888888866532333333333333 PP

  == domain 2  score: 102.9 bits;  conditional E-value: 2.1e-33
  Chromate_transp   3 lflfflkiGllifGGgyavipllreevverkgwlteeefldglalaqalPGPiavnlatfvGyl.......il.gvlGaliatlgfflPsflli 88 
                      lf   + +G+l+fGG+y++ip+++ e+v + gwl ++ fld++a++++lP P+ + +atfvG++       +  ++++++i t+g+++P+f+++
       EEA20063.1 324 LFILGIVAGCLSFGGAYTAIPIIQVEAVLKGGWLPAHVFLDCIAISNVLPAPL-TIFATFVGFQgglvaggLGeAFAASIIITVGILAPCFIFT 416
                      55566678*********************999*********************.5*********8887776445677799************** PP

  Chromate_transp  89 lllaplleklrknplvkaaleglnaavvglilaaalslakk.....................iallaflllllfkvs....pilvillaallg 156
                      ++ + llekl  n++++ +++gl+aav+g+i+ +a++++++                     ++l+++++ +l+k+     p+l+++++a++g
       EEA20063.1 417 IAGHSLLEKLVCNKILSDFFDGLCAAVIGVIAVIAIQILQSsigvptasseivssrsesalaAVLYILAIGALYKFTnkytPLLLVIIGAIAG 509
                      **********88************************998889999999999999999998873344444444444433344899999999987 PP

>> DUF5533  Family of unknown function (DUF5533)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   1.4   9.5e-07    0.0085      38     102 ..     249     314 ..     212     343 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 9.5e-07
     DUF5533  38 ydnfdiylrsrlmygllrlllylsaslltsl.lfvalsvlflleyvsirlllrlqyklsvlllllg 102
                    +    +s+l y+++ l ly  + llts  ++++ ++lf l+yv   +++ ++   s + l lg
  EEA20063.1 249 CASLSCSNKSKLAYSFISLGLYGIIFLLTSHgMWIIATILFTLQYVVYGVYVHFRGVPSPVSLALG 314
                 555677789*******************99658***************999999866666655555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (514 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       881  (0.0491383); expected 358.6 (0.02)
Passed bias filter:                      382  (0.0213063); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3484.52
//
Query:       EEA20064.1  [L=467]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.4e-07   31.5   9.3    3.2e-07   30.4   9.3    1.7  1  Zn_clus      Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
       0.16   12.3   0.2       0.16   12.3   0.2    2.0  2  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
         10    6.8   8.1       0.65   10.6   0.3    3.0  2  zf-C2H2      Zinc finger, C2H2 type


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.4   9.3   5.3e-11   3.2e-07       1      37 [.      55      91 ..      55      94 .. 0.91

  Alignments for each domain:
  == domain 1  score: 30.4 bits;  conditional E-value: 5.3e-11
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfysess 37
                +aC+ C k K +Cd  +P+Cs+C  ++l C + s+s 
  EEA20064.1 55 RACQACTKAKARCDTAFPHCSRCSARSLICHYASDSH 91
                69*****************************777765 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.2   2.6e-05      0.16       3      21 ..      22      40 ..      20      41 .. 0.91
   2 ?   -3.6   0.5       2.7   1.6e+04       4       7 ..      57      60 ..      56      62 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 2.6e-05
                 BBTTTTBBBSSHHHHHCCT CS
  zf-C2H2_jaz  3 YCvlCdKyFksenaldnHl 21
                  C +C+K F + ++l  H 
   EEA20064.1 22 SCLICAKEFYNKKSLVRHT 40
                 6*****************6 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 2.7
                 BTTT CS
  zf-C2H2_jaz  4 CvlC 7 
                 C++C
   EEA20064.1 57 CQAC 60
                 99*9 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.3   0.00011      0.65       2      20 ..      22      40 ..      21      42 .. 0.92
   2 ?   -2.4   2.5       1.5   8.7e+03       6      14 ..      67      75 ..      57      81 .. 0.66

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00011
                EETTTTEEESSHHHHHHHH CS
     zf-C2H2  2 kCpdCgksFkrksnLkrHi 20
                 C +C k F +k +L+rH 
  EEA20064.1 22 SCLICAKEFYNKKSLVRHT 40
                69****************7 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 1.5
                TTEEESSHH CS
     zf-C2H2  6 CgksFkrks 14
                C+  F++ s
  EEA20064.1 67 CDTAFPHCS 75
                666666544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (467 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       617  (0.0344135); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.58u 0.25s 00:00:00.83 Elapsed: 00:00:00.46
# Mc/sec: 3065.58
//
Query:       EEA20065.1  [L=203]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    0.00011   22.5   0.0    0.00015   22.0   0.0    1.2  1  Acetyltransf_1   Acetyltransferase (GNAT) family
  ------ inclusion threshold ------
       0.01   15.8   0.0      0.015   15.3   0.0    1.2  1  Acetyltransf_10  Acetyltransferase (GNAT) domain
      0.044   13.9   0.0       0.17   11.9   0.0    1.9  2  Acetyltransf_9   Acetyltransferase (GNAT) domain


Domain annotation for each model (and alignments):
>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.0   0.0   2.4e-08   0.00015      27     117 .]      79     169 ..      52     169 .. 0.79

  Alignments for each domain:
  == domain 1  score: 22.0 bits;  conditional E-value: 2.4e-08
                     HHHSTTC.EEEE.EEETTEEEEEEEEEEEET....TSTTEEEEEEEEESGGGTTSSHHHHHHHHHHHHHHHTTESEEEE.EEETTEHHHHHHHHH CS
  Acetyltransf_1  27 sfsleae.gllv.aeedgeliGfisllkipd....ekggvayieslaVspeyrgkGlGsaLlealeerareegikkivl.aveedndaairlYek 114
                     +   +++ +l +   +d++l+++  ++ +      + ++++y++ +a +pe+   G+ +a  e ++ rar+eg+   +l av+e   ++  +Ye 
      EEA20065.1  79 F---PPGaELPAsLNDDERLVAYRDMSAKAKkdylNGRKYWYLNMIARHPERKDPGVVRAIFEPYIARARDEGVPI-WLeAVTE---HSKQVYEH 166
                     3...333344444888999***997777777778899*************************************66.9966655...569***99 PP

                     TTE CS
  Acetyltransf_1 115 lGF 117
                     lGF
      EEA20065.1 167 LGF 169
                     **9 PP

>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.3   0.0   2.4e-06     0.015      51     117 ..     115     180 ..      88     182 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 2.4e-06
  Acetyltransf_10  51 gshisllfVdpeyrgqGigkaLleaveeeaekdgikleltvnasp.yavpfYeklGFkavgeeqeenG 117
                       +++ +++ +pe +  G+ +a++e ++++a+++ +   + ++a + + +++Ye+lGFk+v   +  +G
       EEA20065.1 115 YWYLNMIARHPERKDPGVVRAIFEPYIARARDE-GV-PIWLEAVTeHSKQVYEHLGFKTVVTLRMGAG 180
                      4578888889999999**************655.44.899999999*************987776665 PP

>> Acetyltransf_9  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0      0.28   1.7e+03       8      28 ..       8      28 ..       5      39 .. 0.81
   2 ?   11.9   0.0   2.9e-05      0.17      73     127 ..     115     171 ..      89     172 .. 0.85

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.28
                    GGHHHHHHHHHHHTT----H. CS
  Acetyltransf_9  8 edldevlellkyaFqdeespl 28
                    +d+  + +l+  aF ++++ +
      EEA20065.1  8 SDIRTISNLFTLAFRESPPTV 28
                    7899999*******9998875 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 2.9e-05
                     EEEEEEEEE-CCGTTS-HHHHHHHHHHHHHHHTT--EEEE--..SSHHHHHTTT-EE CS
  Acetyltransf_9  73 aagvtgVavapehrgrgvlskLlaraleemreegqplsllfP..ssipiYrrfGyei 127
                     + ++ ++a +pe +  gv++++ +  ++++r+eg+p+ l      s ++Y+++G+++
      EEA20065.1 115 YWYLNMIARHPERKDPGVVRAIFEPYIARARDEGVPIWLEAVteHSKQVYEHLGFKT 171
                     5678899*****************************987777555569******987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (203 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       329  (0.0183502); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.44
# Mc/sec: 1381.66
//
Query:       EEA20066.1  [L=253]
Description: hypothetical protein PMAA_039330 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (253 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       567  (0.0316247); expected 358.6 (0.02)
Passed bias filter:                      429  (0.0239277); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.39u 0.27s 00:00:00.66 Elapsed: 00:00:00.40
# Mc/sec: 1921.03
//
Query:       EEA20067.1  [L=221]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.8e-15   55.4   0.4    1.3e-14   54.2   0.4    1.6  1  DUF3425   Domain of unknown function (DUF3425)


Domain annotation for each model (and alignments):
>> DUF3425  Domain of unknown function (DUF3425)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.2   0.4   7.3e-19   1.3e-14      16     118 ..     132     218 ..     121     221 .] 0.88

  Alignments for each domain:
  == domain 1  score: 54.2 bits;  conditional E-value: 7.3e-19
     DUF3425  16 ek.lpenlrPtelQlriaHpveidvlpwpelRdrllrafqeeeidedeffrdvvstlivWsieeeeletaeissaelsagdvtdlegWelkesFfrkYp 113
                 +  +p +l+Pt lQl + Hp +id +p+pe+Rd+l++a +   ++e++f+rd+                 ++s++ ++ g  +d+  W + e F  k+ 
  EEA20067.1 132 DPsIPSTLQPTVLQLMTIHPTWIDRFPFPEMRDNLINAISL--VEEEDFLRDLF---------------CMSSFKIKPGGATWDPDAWIIGEAFRAKWG 213
                 4449*********************************8888..9*********5...............35688899*********************9 PP

     DUF3425 114 ylvdg 118
                  l+++
  EEA20067.1 214 FLFTE 218
                 99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (221 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       421  (0.0234815); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1480.65
//
Query:       EEA20068.1  [L=221]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.8e-15   55.4   0.4    1.3e-14   54.2   0.4    1.6  1  DUF3425   Domain of unknown function (DUF3425)


Domain annotation for each model (and alignments):
>> DUF3425  Domain of unknown function (DUF3425)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.2   0.4   7.3e-19   1.3e-14      16     118 ..     132     218 ..     121     221 .] 0.88

  Alignments for each domain:
  == domain 1  score: 54.2 bits;  conditional E-value: 7.3e-19
     DUF3425  16 ek.lpenlrPtelQlriaHpveidvlpwpelRdrllrafqeeeidedeffrdvvstlivWsieeeeletaeissaelsagdvtdlegWelkesFfrkYp 113
                 +  +p +l+Pt lQl + Hp +id +p+pe+Rd+l++a +   ++e++f+rd+                 ++s++ ++ g  +d+  W + e F  k+ 
  EEA20068.1 132 DPsIPSTLQPTVLQLMTIHPTWIDRFPFPEMRDNLINAISL--VEEEDFLRDLF---------------CMSSFKIKPGGATWDPDAWIIGEAFRAKWG 213
                 4449*********************************8888..9*********5...............35688899*********************9 PP

     DUF3425 114 ylvdg 118
                  l+++
  EEA20068.1 214 FLFTE 218
                 99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (221 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       421  (0.0234815); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.25s 00:00:00.64 Elapsed: 00:00:00.37
# Mc/sec: 1787.97
//
Query:       EEA20069.1  [L=294]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.6e-06   28.1   1.5    5.3e-06   26.4   1.5    2.0  1  WW          WW domain
  ------ inclusion threshold ------
        7.6    6.7  55.0         20    5.4  24.7    3.6  2  Extensin_2  Extensin-like region


Domain annotation for each model (and alignments):
>> WW  WW domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.4   1.5   5.9e-10   5.3e-06       1      31 []      15      45 ..      15      45 .. 0.99

  Alignments for each domain:
  == domain 1  score: 26.4 bits;  conditional E-value: 5.9e-10
                X-TTEEEEE-TTTT-EEEEETTT--EESS-- CS
          WW  1 LPpGWeeqwdpdsGrvYYyNheTgetqWekP 31
                LPp+W++qw p+ +++ ++N++Tg+ +W +P
  EEA20069.1 15 LPPDWKAQWVPEENQYMFINERTGQRSWHHP 45
                8*****************************9 PP

>> Extensin_2  Extensin-like region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -9.4  52.4         2   1.8e+04       3      58 .]      69     127 ..       7     145 .. 0.84
   2 ?    5.4  24.7    0.0022        20       3      57 ..     103     152 ..     103     162 .. 0.74

  Alignments for each domain:
  == domain 1  score: -9.4 bits;  conditional E-value: 2
  Extensin_2   3 ykspPppekss....Pppp..yvyksPPPpspykYksPPPpvykyksPpPpkkykYksPPPp 58 
                 y  pPp  + +    Pppp    y  PPPp +  Y  PPPp   y+ P+P     Y sP Pp
  EEA20069.1  69 YGGPPPGGRGYgggpPPPPpgSGYGGPPPPGGRGYGGPPPPS--YGGPSPA-GRGYGSPTPP 127
                 777888877777885333323459999999888999999994..5777777.5777777776 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.0022
  Extensin_2   3 ykspPppekssPppp.yvyksPPPpspykYksPPPpvykyksPpPpkkykYksPPP 57 
                 y  pPpp++  P p    y sP Pp++  Y s  Pp + y+ PpP+    Y  P P
  EEA20069.1 103 YGGPPPPSYGGPSPAgRGYGSPTPPQG--YGSGHPP-QGYGAPPPQ---GYGIPAP 152
                 778999999988887567999999976..5555555.337788887...5665555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (294 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2380  (0.132746); expected 358.6 (0.02)
Passed bias filter:                      726  (0.0404931); expected 358.6 (0.02)
Passed Vit filter:                       163  (0.00909142); expected 17.9 (0.001)
Passed Fwd filter:                        22  (0.00122706); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.70u 0.30s 00:00:01.00 Elapsed: 00:00:00.45
# Mc/sec: 1966.46
//
Query:       EEA20070.1  [L=154]
Description: allergenic cerato-platanin Asp F13 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.8e-38  129.2   1.9      1e-37  128.9   1.9    1.1  1  Cerato-platanin  Cerato-platanin


Domain annotation for each model (and alignments):
>> Cerato-platanin  Cerato-platanin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  128.9   1.9   5.6e-42     1e-37       1     117 [.      36     152 ..      36     154 .] 0.99

  Alignments for each domain:
  == domain 1  score: 128.9 bits;  conditional E-value: 5.6e-42
  Cerato-platanin   1 vsvsydtgyddanrsltvvscsdGsnGlitkywptqgavknfpriGGlsaiagwnsancGtcykityngktiyvlaidaagaGfniakkamdel 94 
                      vsv ydt yd+++  +++++csdG+nGl +k ++t g++++fp++G  ++i+gwns+ncG+cy+ityn+ ++yv+ +d++++ f +++ ++d+l
       EEA20070.1  36 VSVQYDTTYDNSAFPISKLACSDGPNGLQNKGYSTLGQLPDFPYVGASPTISGWNSPNCGACYNITYNSVSLYVMGVDSSTSAFVVSQATLDRL 129
                      79******************************************************************************************** PP

  Cerato-platanin  95 tngqaaelGrvdaeveevalsdc 117
                      t+gqa+ lG++ a  + v++s+c
       EEA20070.1 130 TGGQAVALGQITAYCDVVDSSHC 152
                      *********************** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (154 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       570  (0.0317921); expected 358.6 (0.02)
Passed bias filter:                      353  (0.0196888); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.25s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1138.54
//
Query:       EEA20071.1  [L=965]
Description: DUF221 domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-87  293.3  20.7    1.6e-87  293.3  20.7    2.0  3  RSN1_7TM  Calcium-dependent channel, 7TM region, putative pho
    1.3e-41  142.0   1.5    1.3e-41  142.0   1.5    2.2  2  RSN1_TM   Late exocytosis, associated with Golgi transport
    6.8e-34  117.6   1.6    1.3e-33  116.8   1.6    1.5  1  PHM7_cyt  Cytosolic domain of 10TM putative phosphate transpo
    1.6e-26   92.3   0.2    5.4e-26   90.6   0.2    1.9  1  PHM7_ext  Extracellular tail, of 10TM putative phosphate tran
  ------ inclusion threshold ------
      0.094   12.6   0.0       0.29   11.0   0.0    1.8  1  RRM_1     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom


Domain annotation for each model (and alignments):
>> RSN1_7TM  Calcium-dependent channel, 7TM region, putative phosphate
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       1.1   4.1e+03      51      75 ..     152     176 ..     149     179 .. 0.83
   2 ?   -3.8   0.4       1.8   6.3e+03     220     233 ..     285     298 ..     277     326 .. 0.62
   3 !  293.3  20.7   4.5e-91   1.6e-87       2     274 .]     522     794 ..     521     794 .. 0.99

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 1.1
    RSN1_7TM  51 svvtgllPtlllslllallpiilrl 75 
                 +++++llP+l+ + + + l +i+r+
  EEA20071.1 152 ALLSTLLPALVIAGFWFGLFLICRR 176
                 5788999999999999999888876 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 1.8
    RSN1_7TM 220 pfaliyfllgylvy 233
                 ++++iyf+  ++v 
  EEA20071.1 285 VMGIIYFTYVFFVV 298
                 45555665444432 PP

  == domain 3  score: 293.3 bits;  conditional E-value: 4.5e-91
    RSN1_7TM   2 klivtlllvlliifwiipvafvgllsnletltkvlpflkkilelskkllsvvtgllPtlllslllallpiilrllsklqGalsrselelsvvskyfaFl 100
                  ++v   +++liifw+ip a+vg++sn+++l++++pfl+++ +l+  + +++tgllP+++l+ll++l+p+i+rl+++ +G +s s++el ++s+ f+F+
  EEA20071.1 522 MFMVQGGIAALIIFWSIPAAIVGTISNVTYLANLIPFLGWLAHLPGFIEGIITGLLPSAALILLMSLVPPICRLCARKAGLPSLSRVELFTQSAHFCFQ 620
                 577888899********************************99999999************************************************** PP

    RSN1_7TM 101 vvnvFlvftlagtalslleeiidnptsipkllaeslpkasnFfityillqglagaaleLlqlvklilflikrkflsktprdlaerytkppsfdygteyp 199
                 vv+vFlv+t++++a++++++ii+np s+ +lla++lpkasnF+i+y+llqgl++++ +++q+ + ++f i  +f+ +tpr+l++r+t++  +++g+ +p
  EEA20071.1 621 VVQVFLVTTITSAASAAVSQIIKNPLSAKDLLAQNLPKASNFYISYFLLQGLSMSSAAVVQIMSALMFKILSMFFATTPRRLFKRWTQLAGVSWGSILP 719
                 *************************************************************************************************** PP

    RSN1_7TM 200 kvllifvialiYsviaPlilpfaliyfllgylvykyqllyvydtkyesgGklwpralnrllvglvlfqllliglf 274
                 +++++ vial+Ys+iaPlil fa i ++l y +y+y+ll+vyd   +++G ++pral++ll+g++l+++++iglf
  EEA20071.1 720 VFTNMGVIALTYSCIAPLILGFAFIGLFLVYQAYRYNLLFVYDLDIDTKGLIYPRALQHLLTGVYLAEICMIGLF 794
                 *************************************************************************98 PP

>> RSN1_TM  Late exocytosis, associated with Golgi transport
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  142.0   1.5   3.6e-45   1.3e-41       2     156 .]     153     301 ..     152     301 .. 0.97
   2 ?   -3.6   0.4       2.3   8.4e+03       2      23 ..     729     750 ..     728     756 .. 0.78

  Alignments for each domain:
  == domain 1  score: 142.0 bits;  conditional E-value: 3.6e-45
     RSN1_TM   2 lltslvinlvlalvflllFlilRkknkrvYaprtylkg..eeertpplpqkglfgWipallkisdeeilekaGLDayvflrflkmlikiflvlavlali 98 
                 ll++l+++lv+a++++ lFli+R++++r+Y+pr++l +  ++er+p+lp +g+++W+ a+++isd+++l++++LD+y+flrfl+ l+ i++ ++++ ++
  EEA20071.1 153 LLSTLLPALVIAGFWFGLFLICRRNQQRWYSPRSHLPNlhHHERSPELP-RGFLNWFGAFFQISDSHVLHHSSLDGYLFLRFLRNLCIICFAGIIILWP 250
                 799*********************************99*9999999999.************************************************* PP

     RSN1_TM  99 vLlPvnatggegedskesksgldklsisnvsegsnrlwahvvvayiftglvlyllyre 156
                 vLlPv+atgg+g+      s++d++s+snv     r++ahvv+ +i++ +v+++++re
  EEA20071.1 251 VLLPVHATGGAGN------SQMDQFSFSNV-VSPTRYYAHVVMGIIYFTYVFFVVTRE 301
                 *************......79*********.8999*******************9987 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 2.3
     RSN1_TM   2 lltslvinlvlalvflllFlil 23 
                 l+ s +  l+l+++f+ lFl+ 
  EEA20071.1 729 LTYSCIAPLILGFAFIGLFLVY 750
                 5677788899999999999875 PP

>> PHM7_cyt  Cytosolic domain of 10TM putative phosphate transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.8   1.6   3.5e-37   1.3e-33       1     175 [.     324     509 ..     324     510 .. 0.92

  Alignments for each domain:
  == domain 1  score: 116.8 bits;  conditional E-value: 3.5e-37
    PHM7_cyt   1 srTvlvtgiPkelrseeklkeffeelypgkvvesvqivrdvkkldklveerekavrkleaalskykkngkklpkkr....................... 76 
                 srTvl+ ++P++++se+kl++ f +      +++++i+ d+k+l+k v++r+k++ +le+a+ k++++++   + +                       
  EEA20071.1 324 SRTVLFMSVPESYKSEKKLRQVFGDS-----ICRIWITSDCKELNKKVDQRDKLAYSLEKAEIKLIRRANAA-RLKaevtkeknslnvcddyeladplt 416
                 79*********************864.....79***********************************9876.34469********************* PP

    PHM7_cyt  77 ......pthklgflglkligkkvdaidyyrekleeldeeieeerekv...kkkplgaaFvtfesersaaavakqakcaaqiqqssnptl.kpkkwtvel 165
                       p+h+++f+     gkkvd+++yyr++l    +e+ee+++k+   ++k l a+Fv+f+++++a+ +       +q+ ++++p++  p++  +  
  EEA20071.1 417 atkikrPMHRVSFF-----GKKVDSVQYYRSRLAVAIKEVEELQQKHrdgDAKYLTAVFVEFKTQSDAQVA-------LQTLSHHQPMHmTPRYAGIA- 502
                 ************87.....5***************************76666789************9987.......58999999988777777775. PP

    PHM7_cyt 166 APePrDviWe 175
                    Pr+viW+
  EEA20071.1 503 ---PREVIWS 509
                 ...******7 PP

>> PHM7_ext  Extracellular tail, of 10TM putative phosphate transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.6   0.2   1.5e-29   5.4e-26       1      89 [.     865     951 ..     865     955 .. 0.96

  Alignments for each domain:
  == domain 1  score: 90.6 bits;  conditional E-value: 1.5e-29
    PHM7_ext   1 FlkpeiyasyaalrkllpeeyneeeeeyeeelekkaYlhPavtskepllWiprDpagvSkqeieetekvigisdegaeldekgkvewte 89 
                 +++p+ y +ya lr+ +++++ +   ey e++ ++aY++P++t+++p lWiprDp g+S++ei++t+ +i isd+ga+ld ++k++w++
  EEA20071.1 865 WFHPNLYRDYADLRRKVRRDHIQI--EYLEKELADAYYEPCITAETPQLWIPRDPGGLSQEEIRHTSAIISISDHGAHLDVNNKIRWNK 951
                 9******************99877..9************************************************************64 PP

>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   8.1e-05      0.29      43      63 ..     470     490 ..     462     496 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 8.1e-05
                 EEEESSHHHHHHHHHHHTTEE CS
       RRM_1  43 fVeFeskedAekAlealngkk 63 
                 fVeF++++dA+ Al++l + +
  EEA20071.1 470 FVEFKTQSDAQVALQTLSHHQ 490
                 9***************99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (965 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       823  (0.0459033); expected 358.6 (0.02)
Passed bias filter:                      494  (0.0275531); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.70u 0.27s 00:00:00.97 Elapsed: 00:00:00.42
# Mc/sec: 6976.35
//
Query:       EEA20072.1  [L=98]
Description: hypothetical protein PMAA_039370 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (98 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       876  (0.0488594); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.41u 0.26s 00:00:00.67 Elapsed: 00:00:00.43
# Mc/sec: 686.78
//
Query:       EEA20073.1  [L=805]
Description: cell differentiation and development protein Fsr1/Pro11 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.2e-45  155.8   6.6    1.2e-45  155.8   6.6    2.5  2  Striatin     Striatin family
    1.9e-25   88.6  22.4    3.4e-05   24.5   0.5    7.8  8  WD40         WD domain, G-beta repeat
    6.2e-05   23.2   0.1       0.54   10.6   0.0    4.6  4  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
  ------ inclusion threshold ------
      0.041   13.8   0.0      0.077   12.9   0.0    1.4  1  eIF2A        Eukaryotic translation initiation factor eIF2A
      0.076   12.9   0.0       0.21   11.5   0.0    1.7  1  ADH_N_2      N-terminal domain of oxidoreductase
       0.16   10.9   0.0       0.37    9.7   0.0    1.6  1  Ge1_WD40     WD40 region of Ge1, enhancer of mRNA-decapping p
        0.8    9.5  14.1       0.36   10.7   0.1    2.4  2  DUF2570      Protein of unknown function (DUF2570)
        1.5    8.7  20.7        2.2    8.2  20.7    1.2  1  TFIIA        Transcription factor IIA, alpha/beta subunit


Domain annotation for each model (and alignments):
>> Striatin  Striatin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  155.8   6.6   5.5e-49   1.2e-45       1     153 [.      28     172 ..      28     174 .. 0.80
   2 ?    1.2   9.6      0.22     5e+02      57     137 ..     199     288 ..     192     316 .. 0.54

  Alignments for each domain:
  == domain 1  score: 155.8 bits;  conditional E-value: 5.5e-49
    Striatin   1 TLqgvlhFLQtEwhrherdRneweiEraEmkarIakLegerrgaenlkkdlvrrikmLEyalkqerakylklkegtsaakenkkkekeeeeaeeeekse 99 
                 TLqgv++FLQtEwhrherdRn+weiEraEmk+rI++Leg+ r++++l+++l++++kmLE alk+er+ + +l +g + ++ ++   ++e  a+e+ k+ 
  EEA20073.1  28 TLQGVMRFLQTEWHRHERDRNAWEIERAEMKSRIGRLEGDLRTSKRLHESLGKHVKMLEIALKKERETVRSLRNGEKLEEIRD---PKEV-ARESLKHI 122
                 9******************************************************************9777766666554322...2232.23333333 PP

    Striatin 100 eeskskekksakeslkkseaeeesesekrdeksrkksrqlLkqclqEityllti 153
                 +++++++++ + ++l++    +  +++ r++++r+ksr +L++c qE++y++++
  EEA20073.1 123 SQTNKTQTAFLVPELEN----DPAHADFRQDAEREKSRVYLSKCAQEVSYHVIP 172
                 33334444444444544....78999*************************986 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.22
    Striatin  57 mLEyalkqerakylklkegtsaakenkkkekeeeeaeeeekseeeskskekksakeslkks.............eaeeesesekrdeksrkksr 137
                  LE a +q+r+k++++    +++++n + +++  +++++ +++  ++  ++ s++++ +++              +++ s++ ++de+s ++s 
  EEA20073.1 199 SLEEAYHQQRQKQQQQ----QQQQNNIMVRESAMQNHQSMPANYAENPRSAISIAHAERRNlasqtqtnavenfPSDDLSNKGNSDESSLARSS 288
                 6999999999994443....22222223333333333333333333333333333333333455555666666633333444444444444443 PP

>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.7   0.1   3.8e-05     0.086       7      37 ..     385     420 ..     379     420 .. 0.86
   2 !   14.6   0.3   2.1e-05     0.047       6      37 ..     444     488 ..     439     489 .. 0.77
   3 !   16.0   0.3   7.2e-06     0.016       4      37 ..     496     547 ..     494     547 .. 0.90
   4 ?   -2.4   0.0       4.7   1.1e+04      16      38 .]     621     636 ..     610     636 .. 0.75
   5 ?   -0.4   0.1       1.2   2.6e+03       5      33 ..     650     673 ..     647     676 .. 0.68
   6 !    6.5   0.0    0.0073        16       8      38 .]     693     716 ..     686     716 .. 0.80
   7 !   22.8   0.0   5.2e-08   0.00012       1      38 []     720     758 ..     720     758 .. 0.93
   8 !   24.5   0.5   1.5e-08   3.4e-05       2      37 ..     763     803 ..     762     804 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 3.8e-05
                 EESS.SSEEEEE....EETTSSEEEEEETTSEEEEE CS
        WD40   7 ltGH.ssvtsla....fspdgawlasGsdDgtvriW 37 
                 l+GH + v+s+      sp+ + +++GsdDgt++ W
  EEA20073.1 385 LRGHlDVVRSVIftggGSPSEPEICTGSDDGTIKRW 420
                 89**5558***999999999999**********977 PP

  == domain 2  score: 14.6 bits;  conditional E-value: 2.1e-05
                 EEESS.SSEEEEE.......EETTSSE.....EEEEETTSEEEEE CS
        WD40   6 tltGH.ssvtsla.......fspdgaw.....lasGsdDgtvriW 37 
                 t +GH + vtsla       fs  g+      ++sG+ D ++r+W
  EEA20073.1 444 THRGHvGAVTSLAacpaspnFSNGGRAvgdgwVFSGGQDASIRVW 488
                 4589*888*****8777776444444477777899********** PP

  == domain 3  score: 16.0 bits;  conditional E-value: 7.2e-06
                 EEEEESS.SSEEEEE.................EETTSSEEEEEETTSEEEEE CS
        WD40   4 lrtltGH.ssvtsla.................fspdgawlasGsdDgtvriW 37 
                   tl+GH + v++l+                   pd  +lasG+ Dg + +W
  EEA20073.1 496 KATLDGHtDTVWGLCilpgtagsvfgdvcsnyGGPDRILLASGGADGRIIVW 547
                 6799***666***********999999999999999999************* PP

  == domain 4  score: -2.4 bits;  conditional E-value: 4.7
                 EEEETTSSEEEEEETTSEEEEEE CS
        WD40  16 lafspdgawlasGsdDgtvriWd 38 
                 +      ++++s s D ++ ++d
  EEA20073.1 621 V------NFVVSYS-DASILVYD 636
                 5......6777557.99999998 PP

  == domain 5  score: -0.4 bits;  conditional E-value: 1.2
                 EEEESS..SSEEEEEEETTSSEEEEE.ETTSE CS
        WD40   5 rtltGH..ssvtslafspdgawlasG.sdDgt 33 
                  t++G   ++v+s+        ++s  + Dgt
  EEA20073.1 650 ETYDGTpsTGVNSV--------VTSTiGFDGT 673
                 57888874449999........8753444888 PP

  == domain 6  score: 6.5 bits;  conditional E-value: 0.0073
                 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 tG  ++v ++        ++sG +D+ +r++d
  EEA20073.1 693 TGTsGGVEGV--------IISGYEDRYIRFFD 716
                 45544599**........***********998 PP

  == domain 7  score: 22.8 bits;  conditional E-value: 5.2e-08
                 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 gqc++t  +H s ++sl+ spdg+ l+s++ D ++r+W+
  EEA20073.1 720 GQCTYTMLAHpSAISSLSLSPDGRELVSAGHDASLRFWS 758
                 79999999**999*************98877*******5 PP

  == domain 8  score: 24.5 bits;  conditional E-value: 1.5e-08
                 EEEEEEESS...SS..EEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   2 qclrtltGH...ss..vtslafspdgawlasGsdDgtvriW 37 
                 +c++++t H    +  v+s+ +s+dg+w++sG+ Dg v+++
  EEA20073.1 763 SCTQEITSHrlmRGegVCSVVWSRDGRWVVSGGGDGVVKVF 803
                 6888889996652257****************88*****97 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0      0.25   5.6e+02      51      74 ..     621     644 ..     616     655 .. 0.84
   2 ?    4.7   0.0     0.016        36      52      87 ..     702     736 ..     698     737 .. 0.86
   3 !   10.6   0.0   0.00024      0.54      38      89 ..     730     784 ..     723     786 .. 0.85
   4 ?    4.5   0.1      0.02        44      38      66 ..     776     804 ..     773     805 .] 0.90

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.25
  ANAPC4_WD40  51 klLavaysdgevrlldaesgkvvh 74 
                    ++v+ysd ++ ++d  +g+ v 
   EEA20073.1 621 VNFVVSYSDASILVYDTRTGEEVV 644
                  5689****************9876 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.016
  ANAPC4_WD40  52 lLavaysdgevrlldaesgkvvhslsvksekavtcl 87 
                  ++  +y+d  +r++da+sg++  ++ ++ + a+++l
   EEA20073.1 702 VIISGYEDRYIRFFDANSGQCTYTMLAHPS-AISSL 736
                  7889******************99988877.47765 PP

  == domain 3  score: 10.6 bits;  conditional E-value: 0.00024
  ANAPC4_WD40  38 dsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksek...avtclgW 89 
                   s ++sL+ +pdg+ L+ a +d ++r+ + e+  + ++++ ++      v+++ W
   EEA20073.1 730 PSAISSLSLSPDGRELVSAGHDASLRFWSLEKRSCTQEITSHRLMrgeGVCSVVW 784
                  5789*******************************99999887654446777777 PP

  == domain 4  score: 4.5 bits;  conditional E-value: 0.02
  ANAPC4_WD40  38 dsevrsLaWkpdgklLavaysdgevrlld 66 
                  ++ v s+ W+ dg+  + +  dg v++++
   EEA20073.1 776 GEGVCSVVWSRDGRWVVSGGGDGVVKVFS 804
                  677999*******************9876 PP

>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   3.4e-05     0.077      58     159 ..     685     792 ..     654     799 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 3.4e-05
                 SSS.EEEEEE-TTSS-EEEEESSSSCEEEEEECS...CEEEEEEEEES--EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE-TT......-- CS
       eIF2A  58 kegpihdvaWspkskefaviyGkmpakvslfdlk...vkviskleeqkrNtiffspkgklvllaGfgnlaGeleiwdvkkkkkiakaeaan......at 147
                 +e  +h ++  + + e ++i G+ ++ + +fd +   +  ++  + ++  ++  sp g+ ++ aG      +l +w  +k+++ +++ +          
  EEA20073.1 685 EEAVVHGATGTSGGVEGVIISGYEDRYIRFFDANsgqCTYTMLAHPSAISSLSLSPDGRELVSAGHDA---SLRFWSLEKRSCTQEITSHRlmrgegVC 780
                 555577777777788889***************775577777777888899**************876...59**999966655554433211122255 PP

                 EEEE-TTSSEEE CS
       eIF2A 148 lvewspdgryvl 159
                 +v ws dgr+v+
  EEA20073.1 781 SVVWSRDGRWVV 792
                 678999999997 PP

>> ADH_N_2  N-terminal domain of oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   9.3e-05      0.21      43      82 ..     751     790 ..     743     802 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 9.3e-05
     ADH_N_2  43 DPymRgrmndaksyvepvelgdvmrggavgeVveSknpdf 82 
                 D+  R+++ +++s  ++++    mrg++v+ Vv S++ ++
  EEA20073.1 751 DASLRFWSLEKRSCTQEITSHRLMRGEGVCSVVWSRDGRW 790
                 999********************************98765 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.0   0.00016      0.37     180     223 ..     723     766 ..     701     789 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00016
    Ge1_WD40 180 gllkieehsliveaafspdGtalatasedGevkffqvyledeee 223
                 ++  + + s i++ ++spdG  l  a +d  ++f+ +     ++
  EEA20073.1 723 TYTMLAHPSAISSLSLSPDGRELVSAGHDASLRFWSLEKRSCTQ 766
                 4455666689*************************876555444 PP

>> DUF2570  Protein of unknown function (DUF2570)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.1   0.00016      0.36      23      90 ..      59     128 ..      50     137 .. 0.87
   2 ?    0.9   9.3      0.17   3.9e+02      35      79 ..     186     230 ..     181     242 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00016
     DUF2570  23 qkidsLraenkaqaqlieeqqkanqrLteqLeqerqavekqqk..ianelkakveeekeevktilkqesC 90 
                 ++i  L+ + ++  +l e   k  + L ++L++er  v+  ++  + +e++   e ++e +k i +++  
  EEA20073.1  59 SRIGRLEGDLRTSKRLHESLGKHVKMLEIALKKERETVRSLRNgeKLEEIRDPKEVARESLKHISQTNKT 128
                 689999999999999999999******************998632678****************988765 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.17
     DUF2570  35 qaqlieeqqkanqrLteqLeqerqavekqqkianelkakveeeke 79 
                 q +l  eqq   q L e+ +q rq  ++qq+++n++ ++ +  ++
  EEA20073.1 186 QGNLYGEQQLPQQSLEEAYHQQRQKQQQQQQQQNNIMVRESAMQN 230
                 5567779999*******************9999999877665554 PP

>> TFIIA  Transcription factor IIA, alpha/beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2  20.7   0.00097       2.2     108     285 ..     160     346 ..      80     405 .. 0.42

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.00097
       TFIIA 108 ssaataatfslpakleppvqipagvtlqtasgqlykvnvqasgaqqiaaqplqqvvqqsqgsaaqssvaalqaqsqqaqalaepqqq.lekqqqq.qqq 204
                 s+ a++ +      + p  + p  +t q  +g+ly     ++  qq ++++ +q+ q++q++++q+++  + ++   ++ +++p +   +++ +  + +
  EEA20073.1 160 SKCAQEVS----YHVIPASHPPPEFTSQDLQGNLYGE---QQLPQQSLEEAYHQQRQKQQQQQQQQNNIMVRES-AMQNHQSMPANYaENPRSAIsIAH 250
                 22122222....2223333335577777777776654...4444444444444443333333333333333332.122222222222111111111111 PP

       TFIIA 205 qqqqqqqqqvqqqqqe..esqqaqqasqe....qvag.sqvessqtdgaedaleeespv..legelsaeeeagaqkeelsreeidri.re......... 284
                  + ++ ++q+q++  e  +s   ++   +    + +  +++++sq+++++da +e      +++e +a  +         ++++d+i ++         
  EEA20073.1 251 AERRNLASQTQTNAVEnfPSDDLSN---KgnsdESSLaRSSQASQQQKPQDAPSE---TggWNFEEAAPTP---------DVQVDSIpHHrpdtdafpk 334
                 1122222222222222331111222...111122222234445555555544443...2345555544443.........3344444333444444444 PP

       TFIIA 285 ...........e 285
                             
  EEA20073.1 335 anfvppkspprG 346
                 566555544430 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (805 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1965  (0.109599); expected 358.6 (0.02)
Passed bias filter:                      687  (0.0383178); expected 358.6 (0.02)
Passed Vit filter:                        78  (0.00435049); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.82u 0.31s 00:00:01.12 Elapsed: 00:00:00.44
# Mc/sec: 5453.49
//
Query:       EEA20074.1  [L=470]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.9e-53  179.5   1.4    3.4e-53  178.7   1.4    1.4  1  PIG-P            PIG-P
  ------ inclusion threshold ------
       0.18   11.7   2.1       0.29   11.0   2.1    1.3  1  Glyco_trans_2_3  Glycosyl transferase family group 2
       0.33   11.3   9.8       0.58   10.5   9.8    1.3  1  DPM2             Dolichol phosphate-mannose biosynthesis regu


Domain annotation for each model (and alignments):
>> PIG-P  PIG-P
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  178.7   1.4   5.6e-57   3.4e-53       1     121 []     250     413 ..     250     413 .. 0.90

  Alignments for each domain:
  == domain 1  score: 178.7 bits;  conditional E-value: 5.6e-57
       PIG-P   1 treyygFvlyllstlafllyllwallPeevlhalgityypnryWalavpayllmlvlyiyvalaslnlevltppldsletivDeaa............. 86 
                 t+eyygFvlyl+s++afl+yllw++lP+++lh+lgi+yypnr+W+la+pa+l+m+++yiyvala++n+++lt+p++s+e+ivDeaa             
  EEA20074.1 250 TYEYYGFVLYLTSSFAFLMYLLWSYLPSPFLHQLGIYYYPNRWWSLAIPAWLVMFLVYIYVALACYNTGYLTLPMTSIENIVDEAAniavidgkgrrrl 348
                 79************************************************************************************8888888888888 PP

       PIG-P  87 ..............................kveeeeeeeelkeyaseetdavmDlpigeVnevlY 121
                                               ++ + +    +k+++ e+tdavmD+p+g+V+evlY
  EEA20074.1 349 ggseklkpgsatsqtmstaqnrrvpglassNSASGSGYLLWKDVWAESTDAVMDIPVGGVCEVLY 413
                 8887777777777777766666555555442277889999************************9 PP

>> Glyco_trans_2_3  Glycosyl transferase family group 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   2.1   4.8e-05      0.29     131     190 ..     228     308 ..     212     315 .. 0.59

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 4.8e-05
  Glyco_trans_2_3 131 raalrQrkRwayGc...el........eklillvrllgylgsllwsalp......lhlallllfslla....lalvlllll 190
                       aa++  +R a  +   ++        + +++l++++++l+ llws+lp      l +++++  +++     +++++l+++
       EEA20074.1 228 EAAVAKSARIATTVpraSPkvptyeyyGFVLYLTSSFAFLMYLLWSYLPspflhqLGIYYYPNRWWSLaipaWLVMFLVYI 308
                      5555666666666544411233333333456689999***********977755555555555555555543333333333 PP

>> DPM2  Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   9.8   9.8e-05      0.58       6      60 ..     255     308 ..     252     316 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 9.8e-05
        DPM2   6 GlllllvalllfvYYtiwvil.lPfvdedhvlhkyflpreyairipvillvvlllf 60 
                 G++l l++ + f+ Y +w  l  Pf+++      y+++r +++ ip+ l+++l+ +
  EEA20074.1 255 GFVLYLTSSFAFLMYLLWSYLpSPFLHQLG--IYYYPNRWWSLAIPAWLVMFLVYI 308
                 99****************87658***9877..6899************99988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (470 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       631  (0.0351944); expected 358.6 (0.02)
Passed bias filter:                      352  (0.019633); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3256.25
//
Query:       EEA20075.1  [L=357]
Description: oxidoreductase 2-nitropropane dioxygenase family, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.5e-32  113.3   3.9    1.7e-23   83.6   0.5    2.1  2  NMO           Nitronate monooxygenase
    4.4e-06   25.9   2.2    8.9e-05   21.6   2.2    2.2  1  IMPDH         IMP dehydrogenase / GMP reductase domain
    0.00018   20.6   0.4    0.00032   19.8   0.4    1.4  1  FMN_dh        FMN-dependent dehydrogenase
  ------ inclusion threshold ------
      0.074   12.2   0.5       0.23   10.5   0.5    1.7  1  Glu_synthase  Conserved region in glutamate synthase


Domain annotation for each model (and alignments):
>> NMO  Nitronate monooxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.9   0.2     4e-11   1.8e-07      10      52 ..      19      61 ..      15      71 .. 0.92
   2 !   83.6   0.5   3.7e-27   1.7e-23     140     248 ..     142     253 ..     129     268 .. 0.85

  Alignments for each domain:
  == domain 1  score: 30.9 bits;  conditional E-value: 4e-11
         NMO 10 ikppvvqpgmggiskarLaaavsnaGgLGvlasgyltaDrlak 52
                +kp +v ++m  +s+++La avs aGgLG++++g +t D +a+
  EEA20075.1 19 TKPFIVSAPMRIMSGPALAVAVSGAGGLGFIGTGAKTQDSMAD 61
                689999*********************************9975 PP

  == domain 2  score: 83.6 bits;  conditional E-value: 3.7e-27
         NMO 140 iptissvkearkvearG..aDalivqGpeaGGhqGtpevgdkglfaLvpqvldavd...iPviAaGGiidrrgvaaaLalGAsgvqigtrfLltkesda 233
                  + i++  ea+++ ++   +D+++vqG+e+GGh    ++++ gl++L p+v+d  +   iP+ AaGGi d+rg aaaL+lGAsg+ + trfL+++e   
  EEA20075.1 142 WIQIGTLAEAKQLLRSSelPDVIVVQGSESGGHGR--AKDGLGLISLFPEVADLAQgsqIPLFAAGGIADGRGAAAALCLGASGIVMETRFLAASETRI 238
                 4667888888888776666**************65..66669***********999999*************************************999 PP

         NMO 234 kdahkkklleakldd 248
                 +   ++ ++ a   +
  EEA20075.1 239 SRGYQNEVVRADDGA 253
                 887777777766555 PP

>> IMPDH  IMP dehydrogenase / GMP reductase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.6   2.2     2e-08   8.9e-05      37     242 ..      23     234 ..       7     247 .. 0.73

  Alignments for each domain:
  == domain 1  score: 21.6 bits;  conditional E-value: 2e-08
                 EEE-SSTTT-SHHHHHHHHHTTSEEEE-SSS-HHHHHHHHHH....HHTSTTSXB..XTTSXB-EEEEE-SSTTHHHHHHHHHHTT-SEEEEE-STSSS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       IMPDH  37 lvsaamdtvtesemAialareGgigvihknlsieeqaeevkk....vkrspnaak..dekgrllvgaavgvkedalervkalveagvdvlvvdsahghs 129
                 +vsa+m  +++  +A+a++ +Gg+g+i    ++++ ++ +++    v++s+  ++   ++  l +g +    +d+ e ++  +++   + +   a  + 
  EEA20075.1  23 IVSAPMRIMSGPALAVAVSGAGGLGFIGTGAKTQDSMADLREasisVRKSQVFSTlsSDDSVLPIGVGFQLWSDDVEIAADAIKELRPCAAWLFAPRNG 121
                 79*************************999999998888875222266665544422455667778887777887777666666554444444444443 PP

                 H.HHHHHHHHHHHHTTTSEEEEEEE-SHHHHHHHH.HTT-SEEEE-SS-STTBHHHHHCSB---HHHHHHHHHHHHCTCT-EEEEES---SHHHHHHHH CS
                 x.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       IMPDH 130 e.kvleavkeikkkveeveviaGnvataegakaLi.eagadavkvGiGpGsiCttrvvagvGvpqltAvaevaeaakkagvpviaDGGikysgdivkAl 226
                 +    +   +i+ + ++ + i   + t + ak+L+ + +   v v  G+ s    r   g+G   ++   eva+ a+  ++p+ a GGi   +  + Al
  EEA20075.1 122 QkDLDNWSLKIRIASPQTQ-IWIQIGTLAEAKQLLrSSELPDVIVVQGSESGGHGRAKDGLGL--ISLFPEVADLAQGSQIPLFAAGGIADGRGAAAAL 217
                 3044444557777776554.4456777666666651556677778899999999999999987..67789***************************** PP

                 HTT-SEEEES.CCCTTB CS
                 xxxxxxxxxx.xxxxxx RF
       IMPDH 227 aaGadavmlG.sllagt 242
                 ++Ga+ +++  ++la+ 
  EEA20075.1 218 CLGASGIVMEtRFLAAS 234
                 ****9766650555543 PP

>> FMN_dh  FMN-dependent dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.4   7.1e-08   0.00032     249     306 ..     176     233 ..     152     246 .. 0.81

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 7.1e-08
                 TSSTT---HHHCHHHHHHHH...SS-EEEESS--SHHHHHHHHHTT-SEEEESHHHHHH CS
      FMN_dh 249 RqldgapatidvLpeiveavgg.rievlvDgGirrGsDvlkAlalGAdavllGRpflyg 306
                 R  dg    i+  pe+++ ++g +i++++ gGi  G  ++ Al+lGA+++++   fl +
  EEA20075.1 176 RAKDG-LGLISLFPEVADLAQGsQIPLFAAGGIADGRGAAAALCLGASGIVMETRFLAA 233
                 44444.4568899***99999758************************99887666655 PP

>> Glu_synthase  Conserved region in glutamate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.5   5.2e-05      0.23     187     310 ..     122     234 ..     116     245 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 5.2e-05
                   HHHHHHHHHHHHHH-TTSEEEEEEE-STTHHHHHHHHHHTT-SEEEEE-TT.---SSEEHHHHHHB---HHHHHHHHHHHHHHTT-GGG-EEEEESS CS
  Glu_synthase 187 iedlaqliedLkevnkeakvsvKlvaeagvetiaagvakanadiilidGle.GGTGAspkssikhaGlPlelalaevdqtlkeeglrdrvsliadGg 282
                   ++dl +   +++ ++++ ++ + +++ a ++++    ++  +d+i+++G+e GG G +++      Gl l+   +ev     +    +++ l+a+Gg
    EEA20075.1 122 QKDLDNWSLKIRIASPQTQIWIQIGTLAEAKQLLR--SSELPDVIVVQGSEsGGHGRAKD------GLGLISLFPEVA----DLAQGSQIPLFAAGG 206
                   57888888889999999999999988776665544..89999*******86477887665......555555555554....4456789******** PP

                   --SHHHHHHHHHHT-SEEE-SHHHHHHT CS
  Glu_synthase 283 lktgadvvkalalGAdavgigtaalial 310
                   +  g+  + al lGA  + + t  l a 
    EEA20075.1 207 IADGRGAAAALCLGASGIVMETRFLAAS 234
                   ***************9999988887775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (357 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       332  (0.0185175); expected 358.6 (0.02)
Passed bias filter:                      283  (0.0157845); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 2452.76
//
Query:       EEA20076.1  [L=363]
Description: DNA repair protein Rad14, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-25   89.5   3.1    2.1e-25   88.4   3.1    1.6  1  XPA_C     XPA protein C-terminus
  ------ inclusion threshold ------
       0.01   15.8   8.6       0.01   15.8   8.6    2.2  2  XPA_N     XPA protein N-terminal


Domain annotation for each model (and alignments):
>> XPA_C  XPA protein C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.4   3.1   2.4e-29   2.1e-25       1      51 []     208     258 ..     208     258 .. 0.99

  Alignments for each domain:
  == domain 1  score: 88.4 bits;  conditional E-value: 2.4e-29
       XPA_C   1 kysLiTkTeakedYLLtdedLkdrelLkflkkkNPhnstwgdMkLYlklqV 51 
                 kys++TkTea+edYLLtd++Lkd++lL++lkk+NPh+stw+dM+LYl++qV
  EEA20076.1 208 KYSMLTKTEAREDYLLTDPELKDEDLLPHLKKPNPHKSTWNDMMLYLRFQV 258
                 8**********************99*************************9 PP

>> XPA_N  XPA protein N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.8   8.6   1.2e-06      0.01       3      31 ..     176     204 ..     174     204 .. 0.96
   2 ?    1.5   0.3     0.034   3.1e+02       2      10 ..     349     357 ..     348     360 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 1.2e-06
       XPA_N   3 kCdeCgkefldSyLldnFdysVCDkCRDk 31 
                  C eCg+ + d +  + F++ VC++C+Dk
  EEA20076.1 176 ACRECGSLEIDWKWEEAFKCCVCNTCKDK 204
                 6***************************8 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.034
       XPA_N   2 pkCdeCgke 10 
                 ++C eCg e
  EEA20076.1 349 KTCVECGME 357
                 68****965 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (363 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       978  (0.0545485); expected 358.6 (0.02)
Passed bias filter:                      360  (0.0200792); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.41
# Mc/sec: 2626.39
//
Query:       EEA20077.1  [L=242]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.6e-63  211.0   0.1    1.4e-62  210.4   0.1    1.3  1  Blt1      Blt1 N-terminal domain
    1.7e-22   78.7   0.3    3.4e-22   77.8   0.3    1.5  1  Blt1_C    Get5 carboxyl domain


Domain annotation for each model (and alignments):
>> Blt1  Blt1 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  210.4   0.1   1.6e-66   1.4e-62       1     150 []       6     161 ..       6     161 .. 0.97

  Alignments for each domain:
  == domain 1  score: 210.4 bits;  conditional E-value: 1.6e-66
        Blt1   1 FaksflaalDsrpvklsadhveDprsyparvpytLprlskphpempkkvkkaaapgssksitvhlksarnpalelsldnvalattsvkdlkeavqervk 99 
                 F++sfl+++D++p++l++d+v+Dp +++++vpytLprl+ ph++m+kk+k+aaapgs+ks+tv+lksarnp+le+sldnv+l+tt+++dl+eav++r++
  EEA20077.1   6 FTRSFLQSVDTKPIRLPYDYVADPVTTRLPVPYTLPRLQPPHSPMAKKIKTAAAPGSAKSVTVQLKSARNPVLEVSLDNVPLTTTTIHDLREAVRQRTV 104
                 9************************************************************************************************99 PP

        Blt1 100 eae..tkvpldkikiLykkkPv...sgktlaevlas.esevleggkevElgvmvlgG 150
                 +a+  ++ ++dkikiLykkkPv   +++tlae+l++ e+evl+ggk+vE+g+m++gG
  EEA20077.1 105 AADgtQSPAADKIKILYKKKPVggsAERTLAEILGDsEPEVLSGGKTVEFGIMIMGG 161
                 9999677789************77445********999******************9 PP

>> Blt1_C  Get5 carboxyl domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.8   0.3   3.8e-26   3.4e-22       2      50 ..     187     235 ..     186     236 .. 0.96

  Alignments for each domain:
  == domain 1  score: 77.8 bits;  conditional E-value: 3.8e-26
      Blt1_C   2 pkaavgpsgeeVLatEeFWdDLegFleqRvKDeeeaerlrgvFkeAWes 50 
                 +k+a+g+sg+eVL+tEeFW+DLegFle R+KD++e+ rl+g+Fk+AW++
  EEA20077.1 187 SKPAEGASGSEVLQTEEFWKDLEGFLELRTKDTVESLRLAGIFKRAWQA 235
                 799********************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (242 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       366  (0.0204139); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.29s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 1678.80
//
Query:       EEA20078.1  [L=764]
Description: nucleolar RNA methyltransferase (Nop2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.1e-73  244.2   0.0    1.6e-72  243.4   0.0    1.4  1  Methyltr_RsmB-F  16S rRNA methyltransferase RsmB/F
    4.6e-07   30.2   0.0    1.2e-06   28.9   0.0    1.7  1  Methyltr_RsmF_N  N-terminal domain of 16S rRNA methyltransfer
  ------ inclusion threshold ------
      0.023   14.8   0.0      0.045   13.8   0.0    1.4  1  FtsJ             FtsJ-like methyltransferase
        3.3    7.6   6.7       0.43   10.4   1.1    2.5  3  ANTAR            ANTAR domain


Domain annotation for each model (and alignments):
>> Methyltr_RsmB-F  16S rRNA methyltransferase RsmB/F
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  243.4   0.0   3.5e-76   1.6e-72       1     200 []     389     600 ..     389     600 .. 0.94

  Alignments for each domain:
  == domain 1  score: 243.4 bits;  conditional E-value: 3.5e-76
                      HHHH---TT-EEEESS-TTSHHHHHHHHHTTTTSEEEEEESSCCCHHHHHHHHHHTT--SEEEEES-CTC.CHHHHCC..EEEEEEEE--CCGG CS
  Methyltr_RsmB-F   1 allLapqeeetilDlcaaPGgKTthiaelmknkgtvvAvdankeRlkrvaenlkrLgvtntivleaDark.idkvlggelfDriLlDaPCsgtg 93 
                      +++Lapqe+e++lD+++aPGgKTt+i++lm+n+g vvA+da+k R+k ++ n++rLg++ntiv+++ +++ ++k+lgg  fDr+LlDaPC+gtg
       EEA20078.1 389 VMALAPQENERVLDMASAPGGKTTYISALMRNTGIVVANDASKVRTKGLIGNIHRLGCKNTIVCNYNGQEaFPKILGG--FDRVLLDAPCTGTG 480
                      589***************************************************************998637899998..************** PP

                      GTTT-TCHHHH--HHHHHHHHHHHHHHHHHHCCCE....EEEEEEEEEES--STTTTHHHHHHHHHH-TTEEEESSBSTTSTTSSECEEC.... CS
  Methyltr_RsmB-F  94 virrdpdvklrrkekdiaqlaklqkellsaaidll....kkgGvlvYsTCsvlveEneevieeaLkkredvelvetelsepkglklgeea.... 179
                      vi++dp+vk++++e+d+ ++ + q++ll aaid++    k+gG++vYsTCsv+veEne+v++++L+kr++v++v+t l ++    +        
       EEA20078.1 481 VISKDPSVKTNKTERDFLAIPHMQRQLLLAAIDSTdhhsKTGGYIVYSTCSVTVEENEQVVQYVLRKRPNVKIVDTGLGSFGSEGFTSYMgkkf 574
                      ***********************************99***************************************987765544444335566 PP

                      .....TSEEE-TTTTSS-SEEEEEEE CS
  Methyltr_RsmB-F 180 .....gtlrllPhtenkdgffiaklk 200
                            t+r++Ph+en+dgff+ klk
       EEA20078.1 575 dekmtLTRRYFPHRENVDGFFVCKLK 600
                      999999*****************996 PP

>> Methyltr_RsmF_N  N-terminal domain of 16S rRNA methyltransferase RsmF
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.9   0.0   2.6e-10   1.2e-06       9      89 ..     301     385 ..     295     386 .. 0.87

  Alignments for each domain:
  == domain 1  score: 28.9 bits;  conditional E-value: 2.6e-10
                      HHHHHGGGHHHHHHHHH-----EEE--TTS..TTHHHHHHH..-SS--B-.TT-TTEEES---....TTSHHHHTTS-EE--TTT CS
  Methyltr_RsmF_N   9 mkellgeeaeaflaaleeprkkglRvNtlKisveeleklse..efelepv.pwceeGfyleeeerp.gkhplheaGlyYiQEpSa 89 
                      m+ + + ea af++a e pr++ +R+Ntl++++++l+++    ++ l+pv  w++ G  + e++ p g +p++ aG y +Q +S+
       EEA20078.1 301 MSLFTPMEAFAFFEANEIPRPVVIRTNTLRTNRRTLAQALInrGVVLQPVgKWSKVGLQVFESAVPlGATPEYLAGHYILQAASS 385
                      3444455999**********************9999885544799*****77*******99998888*****************8 PP

>> FtsJ  FtsJ-like methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0     1e-05     0.045      21     147 ..     396     543 ..     377     555 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1e-05
                 TT-EEEECT-TTSHHHHHHCCT.T.-SEEEEEESSSS......HHHTTEEEE...CS-CCCSSHHHHHCHCHHHSSEEEEEE--S-SS-CHHHHHHHHH CS
        FtsJ  21 pgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm......aplpgvtti...qgditdpetiekikealserkvdlvvsDgapdvsgvhdldeylq 110
                 ++++v+D ++aPGg + +++  + ++g vva D  ++       ++ ++ +     ++ + +e+ +ki+      ++d v+ D     +gv ++d  ++
  EEA20078.1 396 ENERVLDMASAPGGKTTYISALMRNTGIVVANDASKVrtkgliGNIHRLGCKntiVCNYNGQEAFPKILG-----GFDRVLLDAPCTGTGVISKDPSVK 489
                 5678*******************989********999766444233333332112555555555555554.....477777776554455544444444 PP

                 ...............CCCCHHHHCCHCCCCECCCEEEECCCH..CCCHHHHHHH CS
        FtsJ 111 ...............sqLllaalelalkllkpggtfvlkifr..geeteallkq 147
                                 qLllaa+  + +  k+gg +v  ++    ee e++++ 
  EEA20078.1 490 tnkterdflaiphmqRQLLLAAIDSTDHHSKTGGYIVYSTCSvtVEENEQVVQY 543
                 455555666667765599****99999999999999987776555555566555 PP

>> ANTAR  ANTAR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.1       1.3   5.6e+03      14      31 ..      17      34 ..      15      35 .. 0.88
   2 ?   10.4   1.1   9.7e-05      0.43      22      44 ..     203     225 ..     200     226 .. 0.93
   3 ?   -3.0   0.0       1.5   6.8e+03      44      54 .]     331     341 ..     329     341 .. 0.76

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1.3
                HHHHHHHHHHHT--HHHH CS
       ANTAR 14 eqAkgiLmeryglsedeA 31
                +qA   L+++++  e+eA
  EEA20078.1 17 DQATINLIKKRKAAEAEA 34
                899999999999999998 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 9.7e-05
                 HHHT--HHHHHHHHHHHHCTTTS CS
       ANTAR  22 eryglsedeAfrlLrklSmdsnv 44 
                 e+++l e+eA + +++++m++n+
  EEA20078.1 203 EQRQLEEEEARQEMQDSAMQTNI 225
                 799******************96 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 1.5
                 S-HHHHHHHH- CS
       ANTAR  44 vklrevAeavv 54 
                 +  r++A+a++
  EEA20078.1 331 TNRRTLAQALI 341
                 56789999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (764 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1546  (0.086229); expected 358.6 (0.02)
Passed bias filter:                      473  (0.0263818); expected 358.6 (0.02)
Passed Vit filter:                        87  (0.00485247); expected 17.9 (0.001)
Passed Fwd filter:                        34  (0.00189637); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.01u 0.33s 00:00:01.34 Elapsed: 00:00:00.47
# Mc/sec: 4890.74
//
Query:       EEA20079.1  [L=512]
Description: acyl-CoA dehydrogenase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.9e-31  109.3   1.2    3.7e-31  108.4   1.2    1.5  1  Acyl-CoA_dh_1  Acyl-CoA dehydrogenase, C-terminal domain
    1.7e-21   76.1   0.1    4.8e-21   74.7   0.1    1.8  1  Cyt-b5         Cytochrome b5-like Heme/Steroid binding domain
    3.6e-17   62.3   0.3    7.3e-17   61.4   0.3    1.5  1  Acyl-CoA_dh_M  Acyl-CoA dehydrogenase, middle domain
    1.2e-07   32.1   0.3    2.4e-07   31.1   0.3    1.5  1  Acyl-CoA_dh_2  Acyl-CoA dehydrogenase, C-terminal domain
    9.9e-07   29.4   0.2      3e-06   27.8   0.0    2.0  2  Acyl-CoA_dh_N  Acyl-CoA dehydrogenase, N-terminal domain
  ------ inclusion threshold ------
      0.031   13.6   0.2       0.56    9.5   0.1    2.2  2  Corona_NS2A    Coronavirus NS2A protein


Domain annotation for each model (and alignments):
>> Acyl-CoA_dh_1  Acyl-CoA dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  108.4   1.2   1.2e-34   3.7e-31       1     148 [.     346     502 ..     346     504 .. 0.93

  Alignments for each domain:
  == domain 1  score: 108.4 bits;  conditional E-value: 1.2e-34
                    TBHHHHHTTTT--S-----..-SHHHHHHHHHHHHHHHTSB-CC-BGGGSHHHHHHHHHHHHHHHHHHHHHHHHHH--------......HHHHHH CS
  Acyl-CoA_dh_1   1 gkGfrvametlnheRlavaaaalglarraleealeyarrrkafgkplidhqlvreklaemaaeleaarllvyraaealdagkpd......raeasm 90 
                    +kGf v+m+++nheR ++aaa ++++r ++ee+l+++++r  f+k+li+++++r+kla+m  ++ea +++++ +++++ ++  +         +++
     EEA20079.1 346 DKGFVVIMSNFNHERYMMAAAVIRMCRVIVEECLKWCNQRLVFNKALIEQPAIRQKLAKMISQVEANQAWLESLTHQMCQMSYAqqakhlAGPIAL 441
                    58**************************************************************************87777777777888999*** PP

                    HHHHHHHHHHHHHHHHHHHHGGGTTS.GGGH..HHHHHHHTHHHHHSSS-HHHHHHHHHHH CS
  Acyl-CoA_dh_1  91 aKlfaselaqevadlamqllGgaGyl.eeyp..verlyrdarvlrigeGtseiqrniiarr 148
                    +K + ++ a e+a++a  ++Gg+G++  +++  +e++ r ++ + i++Gt+ei+ ++  r+
     EEA20079.1 442 LKSYSTQCAGEIASSATNIFGGRGLTqSGMGkiIENFNRGYKFDAILGGTEEILADLGVRQ 502
                    *************************95555589********************99987665 PP

>> Cyt-b5  Cytochrome b5-like Heme/Steroid binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.7   0.1   1.6e-24   4.8e-21       2      73 ..       8      77 ..       7      78 .. 0.95

  Alignments for each domain:
  == domain 1  score: 74.7 bits;  conditional E-value: 1.6e-24
                HHHHTTTECTTEEEEEETTEEEECTTTCCCSTTCSHHHHTTTTSBBHHHHHHTTGGCHHHHHHHHGGEEEEE CS
      Cyt-b5  2 leelskhngkndlwvairgkVYDvskflskhpGgesailkyaGkDateafksvvhsekdaekllkkylvGkl 73
                ++e++khn+ +d+wv+i+ kVYD+s+fl+ hpGg+ ++ + aGkDat++f +  h+++++ k+ k++++G+l
  EEA20079.1  8 RAEVAKHNTADDCWVIIDHKVYDLSDFLDAHPGGNVVLAQVAGKDATADFYQL-HRQEVLTKY-KDLCIGTL 77
                79***************************************************.888889***.77****87 PP

>> Acyl-CoA_dh_M  Acyl-CoA dehydrogenase, middle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.4   0.3   2.5e-20   7.3e-17       1      97 []     244     334 ..     244     334 .. 0.88

  Alignments for each domain:
  == domain 1  score: 61.4 bits;  conditional E-value: 2.5e-20
                    EEE---SS-SS-GGG---EE.EEETT.EEEEEEEEEEEETTTT-SEEEEEEETS-------EEEEEEE..GGGEEE-----BSS-TTS-EEEEEEE CS
  Acyl-CoA_dh_M   1 afalTEpqaGsdvasvktta.aerdggeyvlnGeKiwitnaaiatlalvlartekpdrarglslflvprdapgvsvrrieeklGlrglptgelvfe 95 
                    ++a+TE  aGsdva+++tta ++ dg+ y++nG+K witn++ ++++++ +r     +++g+s++l+pr  +gv  + i++++ +  + t+ ++f+
     EEA20079.1 244 CLAITEAFAGSDVAGLRTTAeKTADGKYYIVNGTKKWITNGMFSDYFVTGCR-----TKKGFSVILIPR-GEGVDTTLIKTSYSTA-AGTAFVQFD 332
                    9*******************88888888************************.....479********5.6789888887766554.568999999 PP

                    .. CS
  Acyl-CoA_dh_M  96 dv 97 
                    +v
     EEA20079.1 333 NV 334
                    86 PP

>> Acyl-CoA_dh_2  Acyl-CoA dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.1   0.3     8e-11   2.4e-07       2     113 ..     362     469 ..     361     472 .. 0.91

  Alignments for each domain:
  == domain 1  score: 31.1 bits;  conditional E-value: 8e-11
                    HHHHHHHHHHHHHHHHHHHHHHHHHCTTT-------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT----HHHHHHHHHHHHHHHHHHHHH CS
  Acyl-CoA_dh_2   2 giaavalGaAraalaefvelarervrassgekladdpatqlalaeaaarldAAralleraaaraealaaagkevtvedraearraaalavelaiaa 97 
                    ++aa+++ ++r  ++e +++ ++r    ++++l ++pa+ ++la++ ++++A +a le+ + ++ +++ a+++    +   +++ +++ ++ a ++
     EEA20079.1 362 MMAAAVIRMCRVIVEECLKWCNQRLV--FNKALIEQPAIRQKLAKMISQVEANQAWLESLTHQMCQMSYAQQA--KHLAGPIALLKSYSTQCAGEI 453
                    789***********************..***********************************8887444444..4668889999*********** PP

                    HHHHHHHCGGGGGBTT CS
  Acyl-CoA_dh_2  98 vdalfeaaGgsalrke 113
                    ++++ +++Gg++l+++
     EEA20079.1 454 ASSATNIFGGRGLTQS 469
                    *************987 PP

>> Acyl-CoA_dh_N  Acyl-CoA dehydrogenase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0     1e-09     3e-06       2      78 ..     114     203 ..     113     234 .. 0.83
   2 ?   -3.2   0.0       4.5   1.4e+04      54      74 ..     461     481 ..     450     496 .. 0.74

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 1e-09
                    HHHHHHHHHHHHHHHHHTHHHHHHHHHHT.SGHHHHHHHHHHTTCTSTTS-..GGGTS--S..........-HHHHHHHHHHHHHH-HHH CS
  Acyl-CoA_dh_N   2 eeqealrdtvrefaeeelaphaaewdeeg.efprelwkklaelGllgitvp..eeygGagl..........dyleaaivaeelaradagl 78 
                    e ++ l++++ref ++ + p a++ +++g  + +el++++ae  +l++ +   e   G+ l          d ++ +iv++e+ r +a +
     EEA20079.1 114 ESHRRLQKAIREFTDKYVTPEAQQKEKDGtYISQELIDRMAETNILAMRLGpgEHLHGRTLlggvvdgkefDSFHDMIVTQEMVRSSARG 203
                    78************************999788899***************8897777877667777777779*************87742 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 4.5
                    GTS--S-HHHHHHHHHHHHHH CS
  Acyl-CoA_dh_N  54 ygGagldyleaaivaeelara 74 
                    +gG+gl+   +  ++e + r+
     EEA20079.1 461 FGGRGLTQSGMGKIIENFNRG 481
                    789999888888888888874 PP

>> Corona_NS2A  Coronavirus NS2A protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0     0.044   1.3e+02      62     107 ..     143     193 ..     131     209 .. 0.80
   2 ?    9.5   0.1   0.00019      0.56     143     227 ..     329     417 ..     315     434 .. 0.66

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.044
                  HHHHHHHHHCGGGG-CEEEEEEE..EEETTEE...EEEEES-HHHHHHHHH CS
  Corona_NS2A  62 efaiqeildelvlyetdividnp..hmlGryl...vlevrGleelheevve 107
                   +  qe++d ++  +  ++   p  h+ Gr l   v++ + ++ +h+ +v 
   EEA20079.1 143 TYISQELIDRMAETNILAMRLGPgeHLHGRTLlggVVDGKEFDSFHDMIVT 193
                  46679*******99998887776669****98666789999******9995 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00019
                  EEEEEE---SS-TT-----EEEE-XXXXXXXXXXXXXX.............XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Corona_NS2A 143 yikeklylkhnnlltdedlelvklGaskidafyesels.............vwcaerlcykngaykssdikgyidldkirgeleiGilkvddeeawae 227
                   +  ++ +  +nll +ed  +v + ++  + +y + ++              wc +rl +          k  i    ir +l   i +v+ ++aw e
   EEA20079.1 329 VQFDNVKVPVENLLGEEDKGFVVIMSNFNHERYMMAAAvirmcrviveeclKWCNQRLVF---------NKALIEQPAIRQKLAKMISQVEANQAWLE 417
                  34444445669***************************5555555555554455555555.........55555555555555555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (512 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       803  (0.0447878); expected 358.6 (0.02)
Passed bias filter:                      678  (0.0378158); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.59u 0.24s 00:00:00.83 Elapsed: 00:00:00.40
# Mc/sec: 3804.73
//
Query:       EEA20080.1  [L=371]
Description: deoxyhypusine synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.2e-114  381.6   0.1     2e-113  378.4   0.1    1.9  1  DS        Deoxyhypusine synthase


Domain annotation for each model (and alignments):
>> DS  Deoxyhypusine synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  378.4   0.1  1.1e-117    2e-113       1     287 [.      59     351 ..      59     352 .. 0.96

  Alignments for each domain:
  == domain 1  score: 378.4 bits;  conditional E-value: 1.1e-117
          DS   1 ellesyekigfqatslgeaidilnkmrkdekctiflgltsnlissGlreiiadlvkeklvdvivtTaggieeDlikalgkktylgdfelddeeLrekgi 99 
                 el+++++++gfqa+++gea++i+n+mr+ ++           +  G+  ++ + +++k+v++ivtTagg+eeDlik+l++ tylg f++ ++ Lr +g+
  EEA20080.1  59 ELVSNMSTMGFQASAIGEAVRIINDMRAFRD---------PETGEGTTIFMGYTIQHKHVSAIVTTAGGVEEDLIKCLAP-TYLGVFSTPGAGLRAQGL 147
                 69************************65444.........44455666677788**************************.****************** PP

          DS 100 nRignllvpnenyckfedwvreildkleeeqk................vwspselikelGkeindeeSilywAykndipvfcpaltDgslGdqlllfhs 182
                 nRignl+vpn+nyc+fedw+ +ildk+ +eq+                +w+ps++i++lGkein+eeS++ywA+kndip+fcpaltDgslGd +l+fh+
  EEA20080.1 148 NRIGNLIVPNSNYCAFEDWLIPILDKMVDEQEdskvaaaksgdpddelHWTPSKIINRLGKEINNEESVCYWAWKNDIPIFCPALTDGSLGD-MLYFHT 245
                 ******************************999***********************************************************.****** PP

          DS 183 vk.ekkklkldivkDirelndialkakktgaiilGGGvpKhhilnanlmrngadyavyittaqefdGslsgatldEavSwgkikaeaksvkvyaDaTiv 280
                 +k ++k+l++div+D+r++n+++++ak++g+iilGGG++Khhi+na+lmrnga+ avyi+taqefdGs++ga++dEavSwgkika+a+svkvya+aT++
  EEA20080.1 246 FKtSPKRLRVDIVDDVRRINTMSVRAKRAGMIILGGGIVKHHIANACLMRNGAESAVYINTAQEFDGSDAGARPDEAVSWGKIKAGADSVKVYAEATVA 344
                 *99************************************************************************************************ PP

          DS 281 lPLlvaa 287
                 +PL+va+
  EEA20080.1 345 FPLIVAS 351
                 *****97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (371 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       365  (0.0203581); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2507.86
//
Query:       EEA20081.1  [L=1337]
Description: MATH and UCH domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-16   59.5  26.0    5.7e-06   25.9   0.6    4.5  4  MORN           MORN repeat
    6.9e-16   58.5   0.0    1.4e-15   57.5   0.0    1.4  1  UCH            Ubiquitin carboxyl-terminal hydrolase
    2.7e-10   40.0  10.8    4.3e-10   39.3  10.8    1.3  1  zf-C3HC4_3     Zinc finger, C3HC4 type (RING finger)
    3.7e-05   23.2   0.0    9.3e-05   21.9   0.0    1.6  1  USP7_ICP0_bdg  ICP0-binding domain of Ubiquitin-specific prot
  ------ inclusion threshold ------
      0.014   15.2  10.2      0.027   14.3  10.2    1.4  1  Prok-RING_4    Prokaryotic RING finger family 4
       0.68    9.9  11.4        1.3    9.0  11.4    1.5  1  zf-RING_5      zinc-RING finger domain


Domain annotation for each model (and alignments):
>> MORN  MORN repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   1.3   4.8e-06     0.014       1      22 [.    1193    1214 ..    1193    1215 .. 0.93
   2 !   25.9   0.6   1.9e-09   5.7e-06       1      23 []    1216    1238 ..    1216    1238 .. 0.97
   3 !   20.1   0.4   1.3e-07    0.0004       1      16 [.    1239    1254 ..    1239    1255 .. 0.96
   4 !   12.4   4.1   3.8e-05      0.11       1      18 [.    1263    1280 ..    1263    1281 .. 0.95

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 4.8e-06
        MORN    1 YeGeWknGkrhGkGvytwpdGd 22  
                  Y+Ge+++G  hGkG+ +  +G+
  EEA20081.1 1193 YSGEFSKGYYHGKGTHISDTGT 1214
                  9**************9999998 PP

  == domain 2  score: 25.9 bits;  conditional E-value: 1.9e-09
        MORN    1 YeGeWknGkrhGkGvytwpdGdr 23  
                  Y Ge+  G+rhG+G++ +p+Gd+
  EEA20081.1 1216 YVGEFIFGQRHGQGKMEYPSGDT 1238
                  99*******************96 PP

  == domain 3  score: 20.1 bits;  conditional E-value: 1.3e-07
        MORN    1 YeGeWknGkrhGkGvy 16  
                  YeG+W++++rhG+G++
  EEA20081.1 1239 YEGDWVEDQRHGQGTF 1254
                  ***************8 PP

  == domain 4  score: 12.4 bits;  conditional E-value: 3.8e-05
        MORN    1 YeGeWknGkrhGkGvytw 18  
                  Y G +k+GkrhGkG+ +w
  EEA20081.1 1263 YVGGYKDGKRHGKGISYW 1280
                  99************9988 PP

>> UCH  Ubiquitin carboxyl-terminal hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.5   0.0   4.8e-19   1.4e-15      20     243 ..     452     691 ..     446     701 .. 0.78

  Alignments for each domain:
  == domain 1  score: 57.5 bits;  conditional E-value: 4.8e-19
                 HTSHHHHHHHHTCHHCCSSTCCCCC-.TT.TTS.TTHHHHHHHHHHHHHH..SH-CCEE--HHHHHHHHHHSGGGTSSSTCEHHHHHHHHHHHHHHHHC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         UCH  20 fsipelrdyllsleevkkesrnkkelnesnplgkkgelakalkdlfkell..kskskavsPkklkktlsklaksfsgykqqDaqEflaflLdqlhedln 116
                 ++++++r++++s     ++++++ ++n      k + l +al++++  l   + ++++v ++k+++tl++l++        D+ Ef++ +  +l+ +l+
  EEA20081.1 452 VNLAPFRKIIQS----VDVQEHRRNCN-----VKPRPLCEALQEFLWRLRhqNPENQCVDTDKVTSTLRNLHEY-----SSDVVEFWERMRRTLEIELE 536
                 678888888888....34455554443.....4455799999999999999877899*************9999.....79****************** PP

                 C..........................HCCCHHHHHHCCCTTSHHHHHH-EEEEE..............................EEEEEEB-SEEEEE CS
                 x..........................xxxxxxxxxxxxxxxxxxxxxxxxxxxx..............................xxxxxxxxxxxxxx RF
         UCH 117 r..........................evaeekwkkhlkrndslitdlfegqlks..............................klklkrlPeiLiih 159
                                                                       +                              +   ++lP++L+++
  EEA20081.1 537 GtgaveelaqlfdsppvavsdpqgsnvT--------------------------HtlptqlitsvripvdkektiqgalgryfkeQSGKWSLPPVLHVE 609
                 *666665555554444444433333330..........................2333333335666666666666666666666************** PP

                 EESEEETEE...EEE--SEEB--SEEE-GGGBSS-BTTS-TCS-BEEEEEEEEEESCTTSEEEEEEEE.CTTTTEEEEEETTEEEEE- CS
                 xxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxx RF
         UCH 160 lkRfsynss...ksKlntkvefpeeldlssylaeekkkkteekkkYeLiavvvHsGslssGHYvayik.nekngkWykydDetvkevk 243
                 l+R ++++s   ++ l ++v+  e ldl++y+a++++++      Y+L+++v+H+G   sG+++++ +     +kW+ +dD + ++v+
  EEA20081.1 610 LNRQRFDQSarqWKLLYNRVDLDEVLDLAPYVASGQSSE------YDLYGFVIHRGRRTSGKFFSILRpGGPGSKWVAFDDGSHNRVE 691
                 ******999898888999***************999887......********************9994334566******9887775 PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.3  10.8   1.4e-13   4.3e-10       3      49 ..    1288    1330 ..    1286    1331 .. 0.94

  Alignments for each domain:
  == domain 1  score: 39.3 bits;  conditional E-value: 1.4e-13
                  SB-TTTSSSBS-EEETTEEEEEE-HHHHHHHHHTT-B-TTT--B--E CS
  zf-C3HC4_3    3 eeCviClerprnvvllpCgHlvlCeeCaekllkrkkkCpiCrrpiek 49  
                  ++C+iC+ +++++++++CgH+++C +Ca+++    + CpiCr+++ k
  EEA20081.1 1288 DLCQICYGEEQDALFYDCGHVCACVTCAREV----EICPICRKNVLK 1330
                  68*****************************....********9866 PP

>> USP7_ICP0_bdg  ICP0-binding domain of Ubiquitin-specific protease 7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.9   0.0   3.1e-08   9.3e-05      59     150 ..    1058    1145 ..     962    1169 .. 0.80

  Alignments for each domain:
  == domain 1  score: 21.9 bits;  conditional E-value: 3.1e-08
  USP7_ICP0_bdg   59 keddillFlKlfdpekqtLsyvghvyvskeskvsdlvpeineraglpsdtelllyEEikpnmieilklkqtlkkaelqdGdIicfqkelsee 150 
                     +  ++  F+ +fd+ekq L+ +g ++ s +++v   ++ei++ +g++ ++++l++  i ++ +  + +++t++   + dG+  ++  +l++e
     EEA20081.1 1058 SVPHVYYFIQIFDTEKQALKPAGAFISSLSDNV---MSEIRKNMGWEDNKDFLMWSRIDNTSVVAVSPSDTFS-MSVGDGHCFVVGDRLNKE 1145
                     4456888******************99977765...78**********************************5.568888887777766664 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3  10.2   8.9e-06     0.027       1      40 [.    1290    1328 ..    1290    1333 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 8.9e-06
  Prok-RING_4    1 CvlCgeqekkailepCgHl.vCkeCfdskdlssCPlCqrri 40  
                   C +C  +e++a +  CgH+  C +C  +   + CP+C++++
   EEA20081.1 1290 CQICYGEEQDALFYDCGHVcACVTCAREV--EICPICRKNV 1328
                   9******************99****8765..56*****997 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0  11.4   0.00045       1.3       2      44 .]    1290    1326 ..    1289    1326 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00045
   zf-RING_5    2 CnkCfeklskeekfyltsCgHi.fCekClkkllekeavCpiCrk 44  
                  C++C+    +e+++ +  CgH+ +C +C+++       CpiCrk
  EEA20081.1 1290 CQICYG---EEQDALFYDCGHVcACVTCAREVE----ICPICRK 1326
                  555555...5599*********88*********....*****97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1337 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1161  (0.0647554); expected 358.6 (0.02)
Passed bias filter:                      556  (0.0310112); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                        28  (0.00156172); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.17u 0.31s 00:00:01.48 Elapsed: 00:00:00.49
# Mc/sec: 8222.24
//
Query:       EEA20082.1  [L=2011]
Description: MYB DNA-binding domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-13   50.6   0.0    3.9e-10   39.8   0.0    2.4  2  Myb_DNA-binding  Myb-like DNA-binding domain
     0.0046   16.8   0.0     0.0046   16.8   0.0    3.2  4  Myb_DNA-bind_7   Myb DNA-binding like
     0.0097   16.1   0.2       0.63   10.3   0.1    2.6  2  Myb_DNA-bind_6   Myb-like DNA-binding domain


Domain annotation for each model (and alignments):
>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.8   0.0   6.5e-14   3.9e-10       3      44 ..     985    1026 ..     983    1028 .. 0.95
   2 !    8.5   0.0   0.00039       2.3       4      44 ..    1283    1323 ..    1280    1324 .. 0.84

  Alignments for each domain:
  == domain 1  score: 39.8 bits;  conditional E-value: 6.5e-14
                       SSBHHHHHHHHHHHHHHTTCHHHHHHHHTSS-HHHHHHHHHH CS
  Myb_DNA-binding    3 kWteeEdelLleavkkhGnrWkkIaerlggRtekqcrsrwrn 44  
                        +teeE++l+ +a+  + ++W kIa++l+gRt  qc+s++++
       EEA20082.1  985 DFTEEEHKLFTDAFMAYPKKWGKIADELPGRTYAQCISHYYM 1026
                       69**************************************97 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00039
                       SBHHHHHHHHHHHHHHTTCHHHHHHHHTSS-HHHHHHHHHH CS
  Myb_DNA-binding    4 WteeEdelLleavkkhGnrWkkIaerlggRtekqcrsrwrn 44  
                       W+  E   +  +++ +G +++ I++ + ++t+ ++++++++
       EEA20082.1 1283 WSVPEVRDFPILLAHFGRDFEGISNFMKTKTPIMVKNYYQR 1323
                       6666666666678899***********************95 PP

>> Myb_DNA-bind_7  Myb DNA-binding like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.8   1.5         3   1.8e+04      52      84 ..     820     852 ..     819     854 .. 0.68
   2 ?    0.7   0.2     0.085   5.1e+02       9      74 ..     984    1051 ..     978    1064 .. 0.81
   3 ?   -7.9   5.6         3   1.8e+04      68      82 ..    1138    1151 ..    1131    1157 .. 0.32
   4 !   16.8   0.0   7.7e-07    0.0046       3      51 ..    1275    1323 ..    1273    1344 .. 0.89

  Alignments for each domain:
  == domain 1  score: -4.8 bits;  conditional E-value: 3
  Myb_DNA-bind_7  52 Eerknpeliekalkkrkeldleefkeeaekeke 84 
                     E+ k  e+i++a+++    + ++ +e++++++e
      EEA20082.1 820 ENIKTHERIQEAIRNTVAKQRKDASEKNKRLRE 852
                     666778889999888887666666666666554 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.085
  Myb_DNA-bind_7    9 kkWskeetekFYkaLsqfGtDFsliaklfpkrtrrqlKlKF..kkEerknpeliekalkkrkeldlee 74  
                      ++ ++ee ++F +a   +   +  ia  +p+rt +q  + +   kEe k +++++k  +++++   ++
      EEA20082.1  984 DDFTEEEHKLFTDAFMAYPKKWGKIADELPGRTYAQCISHYymTKEEIKYKAKLNKRWRSQRRARKST 1051
                      56789999999999999999999999999999999988888556899999999999988888765554 PP

  == domain 3  score: -7.9 bits;  conditional E-value: 3
  Myb_DNA-bind_7   68 keldleefkeeaeke 82  
                      ++ + ++ +++ +++
      EEA20082.1 1138 QQ-QQQQQQQQQQQQ 1151
                      22.222222222222 PP

  == domain 4  score: 16.8 bits;  conditional E-value: 7.7e-07
  Myb_DNA-bind_7    3 rkrkktkkWskeetekFYkaLsqfGtDFsliaklfpkrtrrqlKlKFkk 51  
                         ++t+ Ws  e ++F   L  fG DF+ i+++++ +t   +K+ +++
      EEA20082.1 1275 GAMQPTSYWSVPEVRDFPILLAHFGRDFEGISNFMKTKTPIMVKNYYQR 1323
                      5668899**************************************9997 PP

>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.3   0.1   0.00011      0.63       1      41 [.     986    1026 ..     986    1043 .. 0.86
   2 ?    3.0   0.0      0.02   1.2e+02      11      44 ..    1293    1326 ..    1283    1335 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00011
  Myb_DNA-bind_6    1 WteeEdeiLlklvekygndWknIaealnrRtpkqcfdrwkn 41  
                      +teeE ++  +  ++y ++W +Ia++l+ Rt  qc  ++  
      EEA20082.1  986 FTEEEHKLFTDAFMAYPKKWGKIADELPGRTYAQCISHYYM 1026
                      799999999******************55******999876 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.02
  Myb_DNA-bind_6   11 klvekygndWknIaealnrRtpkqcfdrwknkLr 44  
                       l  ++g+d++ I++ ++ +tp  +++++++k++
      EEA20082.1 1293 ILLAHFGRDFEGISNFMKTKTPIMVKNYYQRKID 1326
                      566789***********99***********9775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2011 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1951  (0.108818); expected 358.6 (0.02)
Passed bias filter:                      677  (0.0377601); expected 358.6 (0.02)
Passed Vit filter:                       147  (0.00819901); expected 17.9 (0.001)
Passed Fwd filter:                        48  (0.00267723); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 1.99u 0.41s 00:00:02.40 Elapsed: 00:00:00.65
# Mc/sec: 9295.26
//
Query:       EEA20083.1  [L=343]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (343 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       648  (0.0361426); expected 358.6 (0.02)
Passed bias filter:                      488  (0.0272185); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.55u 0.26s 00:00:00.81 Elapsed: 00:00:00.47
# Mc/sec: 2187.95
//
Query:       EEA20084.1  [L=324]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (324 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       922  (0.0514251); expected 358.6 (0.02)
Passed bias filter:                      700  (0.0390429); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.30s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 2200.21
//
Query:       EEA20085.1  [L=1358]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.2e-36  124.1   0.8      1e-35  123.6   0.1    1.6  2  CHAT      CHAT domain
  ------ inclusion threshold ------
      0.017   15.4   0.2      0.017   15.4   0.2    3.7  4  TPR_12    Tetratricopeptide repeat
      0.025   14.4   0.3       0.33   10.9   0.1    2.9  2  TPR_1     Tetratricopeptide repeat
      0.044   13.8   1.0       0.38   10.9   0.1    2.9  2  MIT       MIT (microtubule interacting and transport) domain
      0.089   13.0   0.2       0.91    9.9   0.2    2.8  1  TPR_8     Tetratricopeptide repeat
      0.098   12.8   3.1       0.25   11.6   0.1    3.5  4  TPR_2     Tetratricopeptide repeat
       0.12   12.5   0.6          1    9.5   0.0    2.8  3  ArfGap    Putative GTPase activating protein for Arf
       0.18   11.2   4.1       0.31   10.4   0.2    2.7  2  SNAP      Soluble NSF attachment protein, SNAP


Domain annotation for each model (and alignments):
>> CHAT  CHAT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.1       2.4   5.4e+03      34      79 ..     833     883 ..     821     927 .. 0.61
   2 !  123.6   0.1   4.4e-39     1e-35       3     289 ..    1027    1348 ..    1025    1349 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 2.4
                 xxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxx RF
        CHAT  34 eLqliPfealvdpdg...rylleryavsyapsarl..lselrkaaasaasa 79 
                 +  ++P+++l + d    +   e++a+ ++ +ar+  l +   ++a+++s+
  EEA20085.1 833 AKLHLPLSILNSYDHshpQVSWEEHALLFMEEARArsLIDSLISSAQQQSD 883
                 555688888888888888888888888888888764444444444444443 PP

  == domain 2  score: 123.6 bits;  conditional E-value: 4.4e-39
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxx RF
        CHAT    3 saraLydlliaPleaeldgqsvrqlvivpdgeLqliPfealvdpdgrylleryavsyapsarllselrkaaasaasalq.....lvvgdpkfdaael 94  
                   + ++ d+l++P++a +  ++  q+++++++ L ++P++alv +  ++l+ + avs +ps+++l  l+k++a +a +       ++ gd + +    
  EEA20085.1 1027 LSGQISDVLLRPFAAII--REKSQIIFSLSQPLTAFPVSALVFDG-KPLVLHAAVSQTPSLTALYHLSKRRAASAMPTVsvftkALAGDQSSE---S 1117
                  567999******99999..9999*******************997.*********************99999999997677775444444433...4 PP

                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        CHAT   95 lrklvfpelpgteaEaeaiakllaegelkvllgeaatesalksalsrryrvvHfatHgvfnanpplqsglvlsaenseedglLtaeeilelnldgae 191 
                  +r  +   lp +  Ea  i+ l+++    +   +++++ +++++++   +++H+ tHg++na +pl s + +      + ++++++ i +   + a 
  EEA20085.1 1118 DRATKETFLPMAGVEAISISNLFST---WPIEASNLSRAQFRDHIQGHTSILHIGTHGTVNAGSPLLSSISIGE----DFRVIDMSPIQS---R-AN 1203
                  57777799***************99...89999************999************************74....889999999999...5.88 PP

                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxx............. RF
        CHAT  192 lVvLsACqtglgevidgegvlgLaralllaGarsviaslwpVddeatalLmkrfyqnlla..glskaeALreaqlkllsgkrdq............. 273 
                  l+v++AC +glg+ + g++vlg+++  l+ G ++ i++l++++d a+  Lm+ fy+++ +  gls+aeALr+aq+++l+ + ++             
  EEA20085.1 1204 LIVFAACLSGLGRATAGNDVLGFTHVVLGTGCQAYIGTLFEISDFASMILMTLFYRQIKDtlGLSLAEALRRAQVEFLHFDDEKatafldqlleawd 1300
                  *******************************************************************************998889************ PP

                  ................................xxxxxxxxxxxxxxxx RF
        CHAT  274 ................................kpshapyyWaaFiliG 289 
                                                      +p +Wa+F l+G
  EEA20085.1 1301 atsmtesgikspedfvpdgkylltlqkmmlpqIDWTSPIFWASFALMG 1348
                  *******************************955556**********9 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.4   0.2   7.6e-06     0.017      12      57 ..     317     360 ..     316     370 .. 0.73
   2 ?   -3.2   0.0       4.9   1.1e+04      18      58 ..     459     497 ..     458     500 .. 0.70
   3 ?   -1.8   0.2       1.7   3.9e+03      10      33 ..     774     797 ..     769     800 .. 0.79
   4 ?    0.2   0.1      0.41   9.2e+02       3      36 ..    1270    1302 ..    1268    1308 .. 0.80

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 7.6e-06
      TPR_12  12 vlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyra 57 
                 v  +l++ +eA++++e+ale+++ + +  + + a++   L+ +++a
  EEA20085.1 317 VKIALKDSEEAFRCYEEALELFETS-NS-SRGKAAVHLRLASILHA 360
                 667899****************877.34.44566666666666553 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 4.9
      TPR_12  18 rydeAlellekaleiarrllGpdhpltattlrnLgrlyral 58 
                 r+d A +++e a+  +++l  + ++ + ++l++ + l+ ++
  EEA20085.1 459 RFDTANACYECAYVCCTEL--GARLPAFIALFARAALQNEM 497
                 6778888888888888877..55666677777777766655 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 1.7
      TPR_12  10 aavlrrlgrydeAlellekaleia 33 
                 a++++   + + A+++l ka++++
  EEA20085.1 774 ATIYLNNAQPEVAFRMLLKARRLI 797
                 778888888888999988888776 PP

  == domain 4  score: 0.2 bits;  conditional E-value: 0.41
      TPR_12    3 atalnnlaavlrrlgrydeAlellekaleiarrl 36  
                  a al ++a+v++   + ++A ++l++ le++ ++
  EEA20085.1 1270 AEAL-RRAQVEFLHFDDEKATAFLDQLLEAWDAT 1302
                  6677.88888888788899**********99876 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.1   0.00015      0.33      14      32 ..     321     339 ..     318     341 .. 0.89
   2 ?   -1.0   0.0      0.82   1.8e+03      18      30 ..     377     389 ..     376     390 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00015
                 TT-HHHHHHHHHHHHHHST CS
       TPR_1  14 lgkydeAleyyekALelnP 32 
                 l++ +eA  +ye+ALel +
  EEA20085.1 321 LKDSEEAFRCYEEALELFE 339
                 8999************976 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.82
                 HHHHHHHHHHHHH CS
       TPR_1  18 deAleyyekALel 30 
                 ++A e+++k L+l
  EEA20085.1 377 QDASEHCDKSLTL 389
                 7899*******87 PP

>> MIT  MIT (microtubule interacting and transport) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.1   0.00017      0.38      18      39 ..     322     343 ..     320     362 .. 0.77
   2 ?   -0.4   0.1      0.54   1.2e+03       7      48 ..     874     917 ..     873     924 .. 0.68

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00017
         MIT  18 gnyeeAlelYkealelLlqalk 39 
                 ++ eeA+++Y+ealel+ +  +
  EEA20085.1 322 KDSEEAFRCYEEALELFETSNS 343
                 6889*************98765 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.54
         MIT   7 lvkkA.veeDnagnyeeAlelYk.ealelLlqalkekneerrel 48 
                 l++ A  ++D++g      + Yk  al +Ll + k+++ +++el
  EEA20085.1 874 LISSAqQQSDEEGRRRMSESIYKrRALTHLLSIHKRTENQDKEL 917
                 566776778888888888888873699******99633344443 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.2   0.00041      0.91      12      30 ..     319     337 ..     316     340 .. 0.90

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00041
                 HHTT-HHHHHHHHHHHHHH CS
       TPR_8  12 lklgdyeeAkeyyekalel 30 
                 + l+d eeA  +ye+alel
  EEA20085.1 319 IALKDSEEAFRCYEEALEL 337
                 679***************8 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       4.4     1e+04      10      25 ..      59      74 ..      58      75 .. 0.83
   2 ?   11.6   0.1   0.00011      0.25      13      33 ..     320     340 ..     317     341 .. 0.90
   3 ?   -3.5   0.0       7.6   1.7e+04      18      30 ..     377     389 ..     376     390 .. 0.86
   4 ?   -1.9   0.2       2.2     5e+03       6      29 ..    1274    1297 ..    1272    1298 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 4.4
       TPR_2 10 ayyklgdyeeAleafe 25
                +++ +g++++A  a++
  EEA20085.1 59 VHMLRGRLNDAYTALD 74
                79999*****998876 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 0.00011
       TPR_2  13 klgdyeeAleafekAleldPn 33 
                 +l+d eeA +++e+Alel ++
  EEA20085.1 320 ALKDSEEAFRCYEEALELFET 340
                 68999*************876 PP

  == domain 3  score: -3.5 bits;  conditional E-value: 7.6
       TPR_2  18 eeAleafekAlel 30 
                 ++A e+++k+l l
  EEA20085.1 377 QDASEHCDKSLTL 389
                 7999*****9987 PP

  == domain 4  score: -1.9 bits;  conditional E-value: 2.2
       TPR_2    6 nlGlayyklgdyeeAleafekAle 29  
                  +++++ +   d e+A +++++ le
  EEA20085.1 1274 RRAQVEFLHFDDEKATAFLDQLLE 1297
                  789999999999********9997 PP

>> ArfGap  Putative GTPase activating protein for Arf
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.0       5.4   1.2e+04      71     105 ..     625     662 ..     618     664 .. 0.73
   2 ?    9.5   0.0   0.00045         1      33     102 ..     826     889 ..     821     902 .. 0.71
   3 ?   -1.7   0.0       1.3     3e+03      50      72 ..     987    1009 ..     983    1014 .. 0.87

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 5.4
                 HTCHHHHHHHHTTTC-TTTSG...-TTCGHHHHHHHHH CS
      ArfGap  71 algNkkaneileaklpkeekr...skssskekreefir 105
                 al N+   +++ a ++ ++     + ++ ++ +++fi+
  EEA20085.1 625 ALDNDISDKFWAADMEFNQAIldgNMDKAESVMHDFIK 662
                 67788899999999987777776677777777777776 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00045
                 EEE-HHHHHHHCCS.TTT--EEETTTS---HHHHHHHHHTCHHHHHHHHTTTC-TTTSG-TTCGHHHHHH CS
      ArfGap  33 vflCieCsgvHrslgvhiskvrsltldkwedeelellkalgNkkaneileaklpkeekrskssskekree 102
                 v++C+eC+  H  l+  +s   s    +we++ l ++++   + + + l ++ ++++++      e r++
  EEA20085.1 826 VIICLECAKLHLPLSILNSYDHSHPQVSWEEHALLFMEEARARSLIDSLISSAQQQSDE------EGRRR 889
                 89************9999999999999**********9766555554444444333333......33333 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 1.3
                  T--EEETTTS---HHHHHHHHHT CS
      ArfGap   50 iskvrsltldkwedeelellkal 72  
                  ++++r +++ kw +e +++++ +
  EEA20085.1  987 TNNIRDIDIRKWATELMQIMRDM 1009
                  6899****************975 PP

>> SNAP  Soluble NSF attachment protein, SNAP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.2   0.00014      0.31     128     174 ..     321     368 ..     316     370 .. 0.87
   2 ?   -0.9   0.1      0.39   8.6e+02     215     248 ..    1269    1302 ..    1254    1306 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00014
                 T--HHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHH.HHHTT-HHHH CS
        SNAP 128 lgdlekAieaYekAaelyeqeeakalankcllkvAel.saelekyekA 174
                 l+d e+A ++Ye+A el+e+ +++     ++l++A++ +a+  +y+ A
  EEA20085.1 321 LKDSEEAFRCYEEALELFETSNSSRGKAAVHLRLASIlHARSYNYAPA 368
                 57999******************************7647777788765 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.39
                  HHHHHHGGG-----------HHHHHHHHHHHHTT CS
        SNAP  215 akralekyeeldpsFassrEakllkdlleaveeg 248 
                    +al + + +   F++ +   +l++llea ++ 
  EEA20085.1 1269 LAEALRRAQVEFLHFDDEKATAFLDQLLEAWDAT 1302
                  5678999999999*****************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1358 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       959  (0.0534888); expected 358.6 (0.02)
Passed bias filter:                      727  (0.0405488); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.97u 0.29s 00:00:01.26 Elapsed: 00:00:00.47
# Mc/sec: 8731.00
//
Query:       EEA20086.1  [L=555]
Description: peptidyl-prolyl cis-trans isomerase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.7e-36  124.8   0.0    7.7e-36  123.8   0.0    1.5  1  Pro_isomerase  Cyclophilin type peptidyl-prolyl cis-trans iso


Domain annotation for each model (and alignments):
>> Pro_isomerase  Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.8   0.0   4.3e-40   7.7e-36       2     158 .]      15     184 ..      14     184 .. 0.84

  Alignments for each domain:
  == domain 1  score: 123.8 bits;  conditional E-value: 4.3e-40
  Pro_isomerase   2 vdietsskGrivieLfadkaPktvenFlklvkegfYdgttFhRvikgfmvqgGdptgkts............ageqekkggesi.........rai 76 
                    v+++t   G+++i Lfa+++P +++nF++++ +g+Y  t+FhR+++gf++qgGdptg++s            +                      +
     EEA20086.1  15 VTLNTT-IGPLHISLFAKQTPLACKNFIQHCLDGYYTDTVFHRIVPGFVIQGGDPTGTGSggssifedpefeY----------DpeardpnekVVL 99 
                    678885.9*************************************************9995555555444332..........1333444444788 PP

  Pro_isomerase  77 pdEit.sklkhkrGalamartgkepnsagsqFfItlkeap.hldgkytvFGkVv.eGmdvvekiekvetde..erpkknvkivsaev 158
                    +dEi+ +  +++rG+++ma+++    + gsqFfItl++++ +++g++t+ G++  +++  v ki+++e  e  +rp+ +vk++ +ev
     EEA20086.1 100 RDEIHsRLRFNRRGLVGMAKSE--DGTYGSQFFITLANTErEMNGQCTMLGRIEgDSIYNVVKIAEAELVEgtDRPVFAVKVTGCEV 184
                    99999666677*********95..7***********99988*************98888888999988777799*********9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (555 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       660  (0.0368119); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 3791.99
//
Query:       EEA20087.1  [L=669]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (669 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       467  (0.0260472); expected 358.6 (0.02)
Passed bias filter:                      278  (0.0155056); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.41
# Mc/sec: 4922.64
//
Query:       EEA20088.1  [L=483]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
     0.0028   17.1   0.3       0.23   10.7   0.0    3.0  2  His_Phos_2  Histidine phosphatase superfamily (branch 2)


Domain annotation for each model (and alignments):
>> His_Phos_2  Histidine phosphatase superfamily (branch 2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.0   0.1    0.0007        13       7      26 ..      30      49 ..      24      50 .. 0.82
   2 !   10.7   0.0   1.3e-05      0.23      75     369 ..      47     330 ..      45     352 .. 0.57

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0007
                EEEE--SBB-SHHHHHHHHH CS
  His_Phos_2  7 vviRHGdRtPkqkvkksvts 26
                v  RHGdRt k++  +s+t+
  EEA20088.1 30 VFHRHGDRTSKSTPPASLTD 49
                678********999988876 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 1.3e-05
                 B-HHHHHHHHHHHHHHHHHCH........TCCHTTSS--TTEEEEEESSHHHHHHHHHHHHHHCHCCC---.....S-TTSTTGGG-TTTTCCCEEEHH CS
  His_Phos_2  75 lthaGrkqaeelGrqfrqrYp........lgLlrlhltykdlkirassegRviaSAaafakGllglegelt.....dllskdkdllddsnaakdlldea 160
                 lt  G+ +  + G +f+ rY         lg+  +  + ++l + a   +  + SAaa+++Gl+++ g  +     + + ++     ++    ++    
  EEA20088.1  47 LTDLGYHEILAAGSKFHDRYIadgsatqiLGIQSETVKLSQLAVSAPLDNVLQNSAAAWLQGLYPPVGGASnqtlrNGTVVEAPFNGYQLIPISITNSG 145
                 8999**********************76666666655559****99999999**************996655555544444555555555555555555 PP

                 HHCCCCHHCTTSHHTCHHHCHHHTGGHCHHHHCHCCCCCH..HHHHHHCHHHCTTEEEE-HHHH...HHHHHHHHHHHHHHCT-TTGGGCTH..HCHHH CS
  His_Phos_2 161 kkklkelltegaeacpafewpikvakrvdelvkylkedmd..eniakrleqlcpgesnllaker...wdklercfyeknkfdiskicdlydemkydalh 254
                   ++++ +++ + +c +     +     d  ++yl+++md  +++a+ +++++++  +l++k+    wd+l+  ++  + +d+   + + +e+  ++l 
  EEA20088.1 146 GGSEDNPWLQSSSSCNNALISSNEFFSSDIYMSYLNSTMDlyKSVAPAVNATFTES-QLSFKNAyviWDLLNVALIHNSTTDYPALSGVSNETMHELLV 243
                 55555555555555544433334444555555555555553344446666665554.666665411144444444444455555555555555555555 PP

                 HHHHHHHHHHHHC........TTTCCCCHHHHHHHHHHHHHHHCTSSSEECCSCCCECS-SEEEEEE-HHHHHHHHHHCTTTTTBTTB.SSS.TTT..H CS
  His_Phos_2 255 nrylkdleelyklakvipqEygigpeeklkiGllllnpllkkilndlqrtreeatperhvrlrlyfthdshiysllnaLglpeelagedslaaldrlsa 353
                  +  ++ +  y+           ++  +   G  l++++l  ++n +           ++rl ++f+   +  s +++ +lp  ++             
  EEA20088.1 244 LANIHEYNLAYNA----------SSTARAIAGAELASEVLLALNNTITSRA-------KARLNVQFGAYATFQSYFGLANLPAADPIF----------- 314
                 5554444444443..........4444555555555555555555555544.......455555555555555555555555544444........... PP

                 CCCS-CT-EEEEEEEE CS
  His_Phos_2 354 spelpymsqivfelye 369
                  ++++y+s++v el  
  EEA20088.1 315 YGIPDYASSMVWELVT 330
                 5555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (483 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       636  (0.0354733); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.24s 00:00:00.81 Elapsed: 00:00:00.42
# Mc/sec: 3484.16
//
Query:       EEA20089.1  [L=397]
Description: DNA replication factor C subunit Rfc3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.9e-17   62.1   0.0    1.3e-16   61.3   0.0    1.5  1  AAA              ATPase family associated with various cellul
    1.9e-16   60.2   0.0    7.3e-16   58.3   0.0    2.0  1  Rep_fac_C        Replication factor C C-terminal domain
    1.6e-11   44.3   1.4    3.4e-11   43.2   0.0    2.2  1  DNA_pol3_delta2  DNA polymerase III, delta subunit
    4.3e-09   36.6   0.0    9.5e-09   35.4   0.0    1.7  1  Rad17            Rad17 P-loop domain
    1.7e-07   31.1   0.1    5.6e-07   29.5   0.0    1.8  2  AAA_30           AAA domain
    6.6e-07   29.6   0.1    3.4e-06   27.3   0.0    2.3  2  AAA_assoc_2      AAA C-terminal domain
    1.1e-06   29.0   0.4    1.2e-05   25.6   0.1    2.8  2  AAA_22           AAA domain
    2.5e-06   27.5   0.2    8.3e-05   22.5   0.0    2.2  2  AAA_11           AAA domain
    2.5e-06   28.0   0.0    8.3e-06   26.3   0.0    1.8  1  AAA_16           AAA ATPase domain
      6e-06   26.3   0.0     0.0006   19.8   0.0    2.3  2  AAA_14           AAA domain
    1.4e-05   25.1   0.2    0.00018   21.5   0.1    2.8  2  AAA_5            AAA domain (dynein-related subfamily)
    3.8e-05   23.5   0.0    6.8e-05   22.7   0.0    1.3  1  AAA_24           AAA domain
    4.7e-05   23.2   0.0    0.00014   21.7   0.0    1.8  1  RuvB_N           Holliday junction DNA helicase RuvB P-loop d
    5.2e-05   23.6   0.1    0.00018   21.8   0.1    1.9  1  AAA_19           AAA domain
    8.8e-05   22.4   0.0    0.00017   21.5   0.0    1.4  1  DNA_pol3_delta   DNA polymerase III, delta subunit
    0.00014   21.7   0.2    0.00063   19.6   0.2    2.1  1  AAA_3            ATPase family associated with various cellul
    0.00018   21.6   0.0      0.047   13.7   0.0    2.3  2  ResIII           Type III restriction enzyme, res subunit
    0.00043   19.5   0.0     0.0008   18.6   0.0    1.4  1  DUF815           Protein of unknown function (DUF815)
     0.0012   19.4   0.0     0.0022   18.5   0.0    1.6  1  AAA_18           AAA domain
     0.0014   18.9   0.0     0.0032   17.7   0.0    1.6  1  AAA_28           AAA domain
     0.0022   17.5   0.0       0.35   10.3   0.0    2.3  2  PhoH             PhoH-like protein
     0.0028   17.1   0.0      0.025   14.0   0.0    2.2  2  TniB             Bacterial TniB protein
     0.0082   15.7   0.0      0.021   14.4   0.0    1.7  1  AAA_25           AAA domain
     0.0094   15.7   0.1       0.09   12.5   0.1    2.1  2  DEAD             DEAD/DEAH box helicase
  ------ inclusion threshold ------
       0.01   15.1   0.0      0.016   14.4   0.0    1.3  1  DUF2075          Uncharacterized conserved protein (DUF2075)
       0.01   15.7   0.0      0.019   14.9   0.0    1.4  1  TK               Thymidine kinase
      0.013   15.2   0.0      0.025   14.3   0.0    1.4  1  Sigma54_activat  Sigma-54 interaction domain
      0.015   15.8   0.0      0.027   15.0   0.0    1.4  1  ABC_tran         ABC transporter
      0.019   14.4   0.0      0.043   13.3   0.0    1.6  1  AAA_7            P-loop containing dynein motor region
       0.02   14.5   0.0      0.035   13.7   0.0    1.4  1  SRP54            SRP54-type protein, GTPase domain
      0.022   14.2   0.2       0.15   11.4   0.2    2.3  2  Mg_chelatase     Magnesium chelatase, subunit ChlI
      0.029   14.8   0.0      0.071   13.5   0.0    1.7  1  RNA_helicase     RNA helicase
      0.041   12.9   0.0       0.11   11.6   0.0    1.6  2  T2SSE            Type II/IV secretion system protein
      0.064   13.0   0.0       0.62    9.8   0.0    2.1  2  IstB_IS21        IstB-like ATP binding protein
      0.069   13.0   0.0       0.11   12.4   0.0    1.3  1  ATPase_2         ATPase domain predominantly from Archaea
      0.072   13.0   0.1        1.2    9.0   0.1    2.3  2  NTPase_1         NTPase
       0.15   11.7   0.0       0.25   10.9   0.0    1.3  1  F_actin_cap_B    F-actin capping protein, beta subunit


Domain annotation for each model (and alignments):
>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.3   0.0   2.6e-19   1.3e-16       1     130 [.      80     209 ..      80     211 .. 0.80

  Alignments for each domain:
  == domain 1  score: 61.3 bits;  conditional E-value: 2.6e-19
                 EEEESSTTSSHHHHHHHHHHHH......THEEEEEETTTCSSS.......STTHHHHHHHHHHHHHHHTS..TSEEEEEETGGGHHHHHTTCCCHHHHH CS
         AAA   1 vllyGppGtGKTllakavakel......gvefleisgsellsk.......yvgesekkirelfkeakeka..kpsilfiDEidalaksrsgseseeeer 84 
                 +llyGppGtGKT+++ a+a+ +       + +le+++s+ +            +s k+i  + + ake++  + + +++DE+da++ +           
  EEA20089.1  80 LLLYGPPGTGKTTTILALARRIygsknmRQMVLELNASDDRGIdvvreqiKTFASTKQIFSVAAPAKENSlgAFKLIILDEADAMTATA---------- 168
                 69*******************7433322477999999999933566655444455666666666678888*555***********9999.......... PP

                 HHHHHHHHHHHTTTSSSTEEEEEEESSGGGSTHHHHSTTSSEEEET CS
         AAA  85 vvnqLlteldgvkkkeskvivigatnrpdkldpallrgRfdrkiei 130
                  + +L + +++++    +  +++++n+ +kl+pall +R++r  + 
  EEA20089.1 169 -QMALRRIMEKYTA---NARFCIIANYTHKLSPALL-SRCTRFRFS 209
                 .*************...5789999************.999987665 PP

>> Rep_fac_C  Replication factor C C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.3   0.0   1.5e-18   7.3e-16       1      86 [.     293     378 ..     293     380 .. 0.97

  Alignments for each domain:
  == domain 1  score: 58.3 bits;  conditional E-value: 1.5e-18
                 --HHHHHHHHHHHHH.T-HHHHHHHHHHHHHHC---HHHHHHHHHHHGCCS..S-HHHHHHHHHHHHHHHHHHHCTH-HHHHHHHHH CS
   Rep_fac_C   1 phpteieeileacln.gdfeeaykklrellvekGysaediltqlhrvvkeqeelpeaqkleilellgeiekrlveGasehlqlsall 86 
                 php++i+ei+ ++l+ +d++ + +++++l++ kG++++dil+ l + + +  e+p+++++  le l+e+e rl+ G+se +q+ +l+
  EEA20089.1 293 PHPSDIREIMTTLLStSDVTSCLNTINTLKMSKGLALADILSALGEQLQTL-EVPAQTRISWLEGLAEVEWRLSGGGSEMVQTGGLV 378
                 8************99***********************************6.7*******************************998 PP

>> DNA_pol3_delta2  DNA polymerase III, delta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.2   0.0     7e-14   3.4e-11       2     162 ..      61     211 ..      60     212 .. 0.83

  Alignments for each domain:
  == domain 1  score: 43.2 bits;  conditional E-value: 7e-14
  DNA_pol3_delta2   2 qeealkilskalksgrlahayLfeGdegigkkelalnlakallceeknetkpcgecksckkieqgkhpDvivi...eteekersikldqireli 92 
                      ++++l  +++ + s rl h +L++G+ g+gk ++ l+la+++  +++ ++          ++ + + +D   i   +++ k    ++ qi ++ 
       EEA20089.1  61 HQDILATINRFIDSHRLPH-LLLYGPPGTGKTTTILALARRIYGSKNMRQ----------MVLELNASDDRGIdvvREQIK-TFASTKQIFSVA 142
                      6678888999999****99.799********************9999866..........555555555444411144444.466677787777 PP

  DNA_pol3_delta2  93 eelsrkpreskkkiiiiedaekmtksAaNalLktlEEPsenaifiLitsdtnklLktirSRcqelkfspl 162
                      + ++++   +  k+ii+++a+ mt+ A+ al +++E   +na f +i++ t+kl + + SRc  ++fspl
       EEA20089.1 143 APAKEN-SLGAFKLIILDEADAMTATAQMALRRIMEKYTANARFCIIANYTHKLSPALLSRCTRFRFSPL 211
                      766555.56899********************************************************98 PP

>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.4   0.0     2e-11   9.5e-09       5      81 ..      42     111 ..      38     194 .. 0.65

  Alignments for each domain:
  == domain 1  score: 35.4 bits;  conditional E-value: 2e-11
       Rad17   5 enelWfekykPekaeelavhkkkieevkewlkadvLesrkkriLLisGPsGCgkstvvkvLskel.giklrewlnpvs 81 
                 +n +W+eky+P  ++e+  h+  +  ++++++++ L++     LL+ GP+G gk+t++  L++   g k   ++  + 
  EEA20089.1  42 DNLPWVEKYRPSSLDEVQGHQDILATINRFIDSHRLPH-----LLLYGPPGTGKTTTILALARRIyGSK---NMRQMV 111
                 6779********************************97.....599***************97541433...222222 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.5   0.0   1.1e-09   5.6e-07      21     118 ..      80     182 ..      65     188 .. 0.74
   2 ?   -2.3   0.0       6.2     3e+03     153     182 ..     227     255 ..     223     258 .. 0.71

  Alignments for each domain:
  == domain 1  score: 29.5 bits;  conditional E-value: 1.1e-09
      AAA_30  21 avltGpAGtGKttalkal.reaweaag...grviglAptgkaAkvLaeelgieastiakllkrlk.grarlepgtllivDEagmvdtkqlaallkaaek 114
                  +l Gp+GtGKtt++ al r+++ +++   + + + A+  +  +v++e++ + ast + +  +   ++++l + +l+i DEa  + ++   al +++ek
  EEA20089.1  80 LLLYGPPGTGKTTTILALaRRIYGSKNmrqMVLELNASDDRGIDVVREQIKTFASTKQIFSVAAPaKENSLGAFKLIILDEADAMTATAQMALRRIMEK 178
                 4688*******99888776899998864433334789**************98888887775555755788888********76655555566666666 PP

      AAA_30 115 agak 118
                 + a 
  EEA20089.1 179 YTAN 182
                 5554 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 6.2
      AAA_30 153 evvRqkeseeraaalalregdaeealeala 182
                 e+vR++ ++  +   +l++gd+++al+ l+
  EEA20089.1 227 ENVRIQ-PQAIESLVRLSKGDMRRALNVLQ 255
                 567774.45555666788899999988776 PP

>> AAA_assoc_2  AAA C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.0     7e-09   3.4e-06       3      54 ..     227     289 ..     225     299 .. 0.76
   2 ?   -0.7   0.0       3.9   1.9e+03      67      77 ..     284     294 ..     277     333 .. 0.64

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 7e-09
                  X.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX............XXXXXXXXXXXXXX CS
  AAA_assoc_2   3 kklkleddalealaeladGDaRkaLnlLElaaeaaeak...........egkieitledleea 54 
                  ++++++++a+e l++l++GD+R+aLn+L+++ +++               +++ it +++ ++
   EEA20089.1 227 ENVRIQPQAIESLVRLSKGDMRRALNVLQACHASSIPLpmrnapkeqppPEHELITDDTIYNC 289
                  6899*************************9887765445666665555555555666666555 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 3.9
                  XXHHHHHHHHH CS
  AAA_assoc_2  67 dehYdliSAlh 77 
                  d  Y++i A h
   EEA20089.1 284 DTIYNCIAAPH 294
                  44444444433 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.1   2.5e-08   1.2e-05       7     117 ..      79     177 ..      74     197 .. 0.78
   2 ?   -0.7   0.0       3.3   1.6e+03      44      68 ..     289     313 ..     267     352 .. 0.58

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 2.5e-08
      AAA_22   7 ilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelkaerlsseellealeqalraravielliiDEaqhlrs 105
                 +l+++G++GtGKTt++  l+++    +  +++r  v++ +++ + + + +++++  +         ++   + +   +++  +++  l+i+DEa+ + +
  EEA20089.1  79 HLLLYGPPGTGKTTTILALARRI---YGSKNMRQMVLELNASDDRGIDVVREQIKTFAST------KQIFSVAAPAKENSLGAFK--LIILDEADAM-T 165
                 799*******************8...4455578888888888888888888888888873......4445666667777777777..**********.8 PP

      AAA_22 106 eealeeLrslln 117
                 ++a   Lr++++
  EEA20089.1 166 ATAQMALRRIME 177
                 888888888876 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 3.3
      AAA_22  44 fvtlpsstsskdllrellralglel 68 
                  + +p++++ +++++ ll+  ++  
  EEA20089.1 289 CIAAPHPSDIREIMTTLLSTSDVTS 313
                 6677777777777777777666433 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5   0.0   1.7e-07   8.3e-05      19      62 ..      79     117 ..      62     149 .. 0.67
   2 ?    3.0   0.1      0.15        73     191     223 ..     156     188 ..     126     189 .. 0.85

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 1.7e-07
      AAA_11  19 itliqGPPGtgKTktivellsqllsrrkseeeksakpriLvCap 62 
                   l+ GPPGtgKT+ti++l ++++       +++++  + + a+
  EEA20089.1  79 HLLLYGPPGTGKTTTILALARRIY-----GSKNMRQMVLELNAS 117
                 4799*******************4.....222333333333344 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.15
      AAA_11 191 evldeaeivltTlsgagsklleklakkfdvviI 223
                  +ldea+   +T + a ++ +ek++++ + +iI
  EEA20089.1 156 IILDEADAMTATAQMALRRIMEKYTANARFCII 188
                 479999999999999999999999999999998 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.3   0.0   1.7e-08   8.3e-06      17     127 ..      70     176 ..      58     202 .. 0.59

  Alignments for each domain:
  == domain 1  score: 26.3 bits;  conditional E-value: 1.7e-08
      AAA_16  17 ervrsgrpelvllsGesGvGKsslvrellralekd...ggiflrgkcdqlesaipysalaqalareellrqllde...aesaeleawrekleealaavp 109
                 + + s+r + +ll+G++G+GK++ + +l+r++ ++   +  +l+ ++ +  ++i    + +++++    +q+ +    a++++l+a++  +++++    
  EEA20089.1  70 RFIDSHRLPHLLLYGPPGTGKTTTILALARRIYGSknmRQMVLELNASDD-RGIDV--VREQIKTFASTKQIFSVaapAKENSLGAFKLIILDEAD--- 162
                 344577789*********************99999776555566666665.44443..44444444444444444222555555555555555544... PP

      AAA_16 110 elagaeasrllellkrll 127
                 +++         +l+r++
  EEA20089.1 163 AMT----ATAQMALRRIM 176
                 222....33333344444 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.0     0.068        33      68      90 ..      53      75 ..      10      81 .. 0.79
   2 !   19.8   0.0   1.2e-06    0.0006       5      98 ..      80     188 ..      77     212 .. 0.68

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.068
      AAA_14 68 lflDEiqevpewekalkslvdeg 90
                  lDE+q  +++  ++++++d++
  EEA20089.1 53 SSLDEVQGHQDILATINRFIDSH 75
                569*****************986 PP

  == domain 2  score: 19.8 bits;  conditional E-value: 1.2e-06
      AAA_14   5 lvitGaRrvGKTtllkqlikell...vkkesilyinldderd.....kkladpekllelileklke..........ekktylflDEiqev.pewekalk 84 
                 l++ G+  +GKTt +  l+++ +     ++ +l++n  d+r      ++++++++  +++     +             ++++lDE+  +  +++ al+
  EEA20089.1  80 LLLYGPPGTGKTTTILALARRIYgskNMRQMVLELNASDDRGidvvrEQIKTFASTKQIF-----SvaapakenslGAFKLIILDEADAMtATAQMALR 173
                 6899***************99998655556666666666555444432222222222222.....1233445566656788******9772578999** PP

      AAA_14  85 slvdeg.knldvivt 98 
                 ++++++  n ++++ 
  EEA20089.1 174 RIMEKYtANARFCII 188
                 ****88778888765 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0       2.6   1.2e+03      71      94 ..      55      77 ..      50      78 .. 0.90
   2 !   21.5   0.1   3.8e-07   0.00018       1      91 [.      79     178 ..      79     184 .. 0.69

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 2.6
                EESGGG--HHHHHHHHHHHHSSEE CS
       AAA_5 71 lDEveraesevlnsLlslleerrl 94
                lDEv+  ++++l++ ++ ++  rl
  EEA20089.1 55 LDEVQ-GHQDILATINRFIDSHRL 77
                89999.99*********9998876 PP

  == domain 2  score: 21.5 bits;  conditional E-value: 3.8e-07
                 EEEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--...........--------.......G-SEEEEESGGG--HHHHHHHHHHHH CS
       AAA_5   1 dvlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreik..ngttslvdsplvraar.......egeilvlDEveraesevlnsLlslle 90 
                 ++lL GppGtgK++ +  la+++  + ++ q+   ++++d +g   ++   +t + +++++  aa          ++++lDE + +   ++++L +++e
  EEA20089.1  79 HLLLYGPPGTGKTTTILALARRIYGSKNMRQMVLELNASDDRGIDVVReqIKTFASTKQIFSVAAPakenslgAFKLIILDEADAMTATAQMALRRIME 177
                 79*********************6666665555555555544444444323344444444444444666777777888899999888888888888877 PP

                 S CS
       AAA_5  91 e 91 
                 +
  EEA20089.1 178 K 178
                 5 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   0.0   1.4e-07   6.8e-05       5      85 ..      80     172 ..      78     185 .. 0.74

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 1.4e-07
      AAA_24   5 iliyGpsgiGKTtlakel........gpkplfidtekGlksldadkfpdieswedfldevvel....aaeladyktlviDtideleelclaev 85 
                 +l+yGp+g+GKTt+++ l          +  ++ ++++ ++  +   ++i++++  ++ +       +  l  +k +++D +d +   +   +
  EEA20089.1  80 LLLYGPPGTGKTTTILALarriygskNMRQMVLELNASDDRGIDVVREQIKTFASTKQIFSVAapakENSLGAFKLIILDEADAMTATAQMAL 172
                 79****************8888887766777777777666544444466777777777766669988888889*********99977665554 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.7   0.0   2.8e-07   0.00014       2      57 ..      51     101 ..      50     113 .. 0.88

  Alignments for each domain:
  == domain 1  score: 21.7 bits;  conditional E-value: 2.8e-07
      RuvB_N   2 rPksleeyigqekvkeklkifieaakkreealdhvllyGpPGlGkttlakiiakel 57 
                 rP+sl+e  g +++ ++++ fi++       l h+llyGpPG Gktt    +a+ +
  EEA20089.1  51 RPSSLDEVQGHQDILATINRFIDSH-----RLPHLLLYGPPGTGKTTTILALARRI 101
                 9*********************975.....589**************888877765 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   0.1   3.8e-07   0.00018       8     126 ..      75     176 ..      69     190 .. 0.68

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 3.8e-07
      AAA_19   8 lkekvllvtaGpGtGKTrvlkhivallvelggvkpeeillvaftgrAakelrerlaalgaeatTiHrlalldfddlltealelleeaeeekklqeeell 106
                 ++ ++ll+ ++pGtGKT+++ +  + +   +++    + l a   r  + +re++       +T+ +      +++ + a+      ++e+ l + +l+
  EEA20089.1  75 HRLPHLLLYGPPGTGKTTTILALARRIYGSKNMRQMVLELNASDDRGIDVVREQI-------KTFAST-----KQIFSVAAP-----AKENSLGAFKLI 156
                 5567899*******************99999887666778899999999999999.......555544.....222211222.....234555333477 PP

      AAA_19 107 ivDEfqdvdelqyrLlkall 126
                 i DE+  ++ +++  l++++
  EEA20089.1 157 ILDEADAMTATAQMALRRIM 176
                 77777777755555555554 PP

>> DNA_pol3_delta  DNA polymerase III, delta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.0   3.4e-07   0.00017      60     170 ..     155     255 ..     148     256 .. 0.86

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 3.4e-07
                     EEEEE--.....TT-S-TTHHHHHHHHTTT--SSEEEEEEES.S--HHHHHHHHHTTTEEEEEE----TTTHHHHHHHHHHHTT-EE-HHHHHHH CS
  DNA_pol3_delta  60 ivvlknpklltkesklnekllkeLeeylsnlpedtlLiliapkklderkklvklLkkkatvveaktlkeeelkkwiqkraqelglkiekealelL 154
                     +++l+ +      +  ++  + +L ++++++ ++  +++ia+       kl   L ++ t +++++lke +++  ++k+++++++ i+++a+e L
      EEA20089.1 155 LIILDEA------DAMTATAQMALRRIMEKYTANARFCIIAN----YTHKLSPALLSRCTRFRFSPLKEVDIRSLVDKVIEAENVRIQPQAIESL 239
                     4555555......55788888899999999999999999999....456777888888999********************************** PP

                     HHHHTT-HHHHHHHHH CS
  DNA_pol3_delta 155 lelvennlsaikqele 170
                     + l+ ++++++ + l+
      EEA20089.1 240 VRLSKGDMRRALNVLQ 255
                     ********99988775 PP

>> AAA_3  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.2   1.3e-06   0.00063       1      88 [.      79     178 ..      79     204 .. 0.73

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 1.3e-06
       AAA_3   1 hvllegvPGlaktllvkalakaldlefkriqftpdllPsdilGtevfeekekefefkkGpvfa.............nllladeinrappktqsalleam 86 
                 h+ll g PG++kt+++ ala+ +  + +  q+  +l  sd  G++v++e+ k+f  +k  +f+             +l++ de +  ++ +q al  +m
  EEA20089.1  79 HLLLYGPPGTGKTTTILALARRIYGSKNMRQMVLELNASDDRGIDVVREQIKTFASTKQ-IFSvaapakenslgafKLIILDEADAMTATAQMALRRIM 176
                 99************************9999******************99987765442.221011111111111246666777777777777776666 PP

       AAA_3  87 ee 88 
                 e 
  EEA20089.1 177 EK 178
                 65 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.7   0.0   9.7e-05     0.047      12      55 ..      64     108 ..      54     117 .. 0.76
   2 ?    5.5   0.0     0.031        15     123     160 ..     143     182 ..     113     189 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 9.7e-05
                 HHHHT.......TTSEEEEEESTTSTHHHHHHHHHHHH-S..... CS
      ResIII  12 ienll.eklkskrdkrglikmaTGtGKTlvaaklierllkkgkee 55 
                 i +++   ++s+r  ++l+  + GtGKT ++++l++r++ +++ +
  EEA20089.1  64 ILATInRFIDSHRLPHLLLYGPPGTGKTTTILALARRIYGSKNMR 108
                 3444414445577779*********************99987655 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.031
                 ....HHHTTT-SEEEEETGGGTTS.T..TTHHHHHT---S CS
      ResIII 123 eeseellrdrfdviiiDEaHrlgakk..swreilekfkea 160
                    +e++ ++f++ii DEa  ++a +  + r+i+ek+ ++
  EEA20089.1 143 APAKENSLGAFKLIILDEADAMTATAqmALRRIMEKYTAN 182
                 467889999**********999996456888998887665 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0   1.6e-06    0.0008      24     104 ..      52     131 ..      37     141 .. 0.72

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 1.6e-06
      DUF815  24 evklddLvgidkqkealventeqfleglpannvLLwGarGtGKSslvkallneyaeeg.Lr..lievekedlkelpklvellre 104
                 + +ld+++g    ++++++ +++f++ ++  ++LL+G  GtGK +++ al +++  ++ +r  ++e++ +d + ++ + e++++
  EEA20089.1  52 PSSLDEVQG----HQDILATINRFIDSHRLPHLLLYGPPGTGKTTTILALARRIYGSKnMRqmVLELNASDDRGIDVVREQIKT 131
                 444444444....45678899*****************************9997665544433667777777777766666665 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.0   4.6e-06    0.0022       2      42 ..      81     121 ..      80     180 .. 0.79

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 4.6e-06
      AAA_18   2 lltGtpGvGKttlakeLskrlgf.gvnlrdvakenglllevd 42 
                 ll G+pG+GKtt   +L++r  + + n r+++ e + ++++ 
  EEA20089.1  81 LLYGPPGTGKTTTILALARRI-YgSKNMRQMVLELNASDDRG 121
                 689*****************6.57777888777766655544 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0   6.6e-06    0.0032       3      61 ..      81     159 ..      79     174 .. 0.60

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 6.6e-06
      AAA_28   3 vitGgestGKTtlleaLa..............ar......gypvvpEaareileeklakgedalpwvedllafaervle 61 
                  + G+++tGKTt++ aLa              +       g+ vv+E   ++ + k+ +   a ++++ l af+  +l+
  EEA20089.1  81 LLYGPPGTGKTTTILALArriygsknmrqmvlELnasddrGIDVVREQIKTFASTKQIFSVAAPAKENSLGAFKLIILD 159
                 589***************4444444444333300334444666666666666666665555433333555555555555 PP

>> PhoH  PhoH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.3   0.0   0.00071      0.35      23      57 ..      81     115 ..      61     131 .. 0.86
   2 ?    4.8   0.0     0.034        17     122     145 ..     155     177 ..     151     197 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00071
                 EEE--TTSSTTHHHHHHHHHHHHTTS-SEEEEEE- CS
        PhoH  23 faiGpaGtGKtylavalavealkkkkvkriiltrp 57 
                    Gp GtGKt   +ala +++ +k++++++l  +
  EEA20089.1  81 LLYGPPGTGKTTTILALARRIYGSKNMRQMVLELN 115
                 678**************************999655 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.034
                 EEEE-SGGG--HHHHHHHHTTB-T CS
        PhoH 122 fvilDEAQnttkeqmkmfltRlGe 145
                 ++ilDEA  +t  + +m l R+ e
  EEA20089.1 155 LIILDEADAMTA-TAQMALRRIME 177
                 7******99885.67899998855 PP

>> TniB  Bacterial TniB protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.0   0.0   5.2e-05     0.025      21      58 ..      63     100 ..      48     141 .. 0.77
   2 ?    0.1   0.0      0.96   4.7e+02     120     143 ..     153     176 ..     149     180 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 5.2e-05
        TniB  21 erLeeLleypkrkrmpnlllvGdsnnGKtmivekFarl 58 
                 + L+ + ++ +++r p+lll+G++ +GKt+ +   ar+
  EEA20089.1  63 DILATINRFIDSHRLPHLLLYGPPGTGKTTTILALARR 100
                 557777888899*****************998666654 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.96
        TniB 120 vrvLiiDEihnllagsarkqrefl 143
                  +++i+DE + + a  + + r+++
  EEA20089.1 153 FKLIILDEADAMTATAQMALRRIM 176
                 589*******99988777666655 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.0   4.2e-05     0.021      37      59 ..      81     103 ..      68     169 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 4.2e-05
      AAA_25  37 llaGapgtGKttlaldlalavat 59 
                 ll+G+pgtGKtt  l la  +  
  EEA20089.1  81 LLYGPPGTGKTTTILALARRIYG 103
                 8*****************99874 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.1      0.44   2.1e+02      17      40 ..      80     102 ..      65     114 .. 0.72
   2 !   12.5   0.1   0.00019      0.09      81     149 ..     101     179 ..      91     187 .. 0.66

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.44
                 EEEEESTTSSHHHHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  17 vlvaaeTGsGKTlaflipvlqivy 40 
                 +l+ ++ G+GKT+  l  + +++y
  EEA20089.1  80 LLLYGPPGTGKTTTILALA-RRIY 102
                 6788999*****9965444.4554 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 0.00019
                 EETTSSHHHHHHHH....HTTCSEEEEEHHHHHHHH.......HCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHS CS
                 xxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  81 iiggvaardqlskl....dngvdivvgtpgrlddll.......stgklnlsqvrflVlDEadrlldqgfsdfinrilnql 149
                 i+g+++ r+ + +l    d+g+d+v    + +++           ++ +l  +++++lDEad +     +  ++ri+++ 
  EEA20089.1 101 IYGSKNMRQMVLELnasdDRGIDVVREQIKTFASTKqifsvaaPAKENSLGAFKLIILDEADAMTAT-AQMALRRIMEKY 179
                 5566666666666644433446666555544444333445556344446***************998.888888888765 PP

>> DUF2075  Uncharacterized conserved protein (DUF2075)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   3.4e-05     0.016       5     106 ..      81     170 ..      79     190 .. 0.64

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 3.4e-05
     DUF2075   5 lVtGvaGtGKtvvllnllael..eddeeertavylsvNhplvlvlrealakkeekkkkkeafeklssfinnlsefkkaeekkeepkedvvivDEAhrll 101
                 l  G +GtGKt   l+l+ ++  +++ ++    +     + ++v+re+++  +       + ++  s+          +++++   ++++i DEA  ++
  EEA20089.1  81 LLYGPPGTGKTTTILALARRIygSKNMRQMVLELNASDDRGIDVVREQIKTFA-------STKQIFSVAA-------PAKENSLGAFKLIILDEADAMT 165
                 6689*****************33333333333333344556678888885444.......2222222223.......3446777899999999999888 PP

     DUF2075 102 tksdq 106
                  ++++
  EEA20089.1 166 ATAQM 170
                 75444 PP

>> TK  Thymidine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   0.0   3.8e-05     0.019       5     100 ..      81     176 ..      79     194 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 3.8e-05
          TK   5 lilgpmfaGKsteLlrrvkr.yqlaekkvvvika.akdnRysegkvvthdgisleakksktssleeikeeleeedvdvvlvDEaqFfe.qdivelsekl 100
                 l++gp  +GK+t++l  ++r y  ++++ +v+   a d+R     v  +++++ ++k  ++ s++   +e +  +++ +++DEa  ++    + l +++
  EEA20089.1  81 LLYGPPGTGKTTTILALARRiYGSKNMRQMVLELnASDDRGID-VVREQIKTFASTK--QIFSVAAPAKENSLGAFKLIILDEADAMTaTAQMALRRIM 176
                 6899999*******99998847788999999886156777774.5777777777777..8888888888888889*********988844444444444 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   5.2e-05     0.025       9     120 ..      62     179 ..      56     184 .. 0.75

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 5.2e-05
                      HHHHHHHHHHCTSS..S-EEEECSTTSSHHH....HHHHHHHHSTTTTS-EEEEETTTS.-TTCHHHHH..HEBSSSSSTTTSS-BEHHHHHTT CS
  Sigma54_activat   9 kelleqikkvaktd..lsvlitGesGtGKel....laraiheaskrkekpfvavncaai.peelleseL..FGhekGaFtGAekekkGlfekad 93 
                      +++l++i+++++++   ++l+ G  GtGK++    lar i+  sk+ ++ ++++n ++    ++++ ++  F  +k  F+ A  +k+  + +  
       EEA20089.1  62 QDILATINRFIDSHrlPHLLLYGPPGTGKTTtilaLARRIYG-SKNMRQMVLELNASDDrGIDVVREQIktFASTKQIFSVAAPAKENSLGAF- 153
                      6777888888888766799**********9722225666665.5556777899999954255677665444********99988887555443. PP

                      TSEEEEETGGGS-HHHHHHHHHHHHHS CS
  Sigma54_activat  94 gGtlfLDeigelplelQekLlrvlqeg 120
                         + LDe   +++++Q  L r++++ 
       EEA20089.1 154 -KLIILDEADAMTATAQMALRRIMEKY 179
                      .3799*****************99986 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.0   0.0   5.5e-05     0.027      14      92 ..      80     175 ..      75     251 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 5.5e-05
                 EEEEESTTSSHHHHHHHHTTSS--..SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSB.HHHH..................HHHTCHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxx..................xxxxxxxxxxxx RF
    ABC_tran  14 vaivGenGaGKStLlkllagllkp..teGeilldgkdlkeqeleslrkeigvlpqepqlfpelt.vren..................esdeeiekalsk 91 
                 + + G+ G+GK+t + +la+      ++ ++ l+ + ++++ + ++r++i+++  ++q+f+    ++en                  +    ++ al++
  EEA20089.1  80 LLLYGPPGTGKTTTILALARRIYGskNMRQMVLELNASDDRGIDVVREQIKTFASTKQIFSVAApAKENslgafkliildeadamtaT----AQMALRR 174
                 5689***************9987744566778888999999*****************999999888889999999998876644331....2222222 PP

                 S CS
                 x RF
    ABC_tran  92 l 92 
                 +
  EEA20089.1 175 I 175
                 2 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0     9e-05     0.043      35      71 ..      79     116 ..      65     132 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 9e-05
       AAA_7  35 pvllvGptGtGKtviikdllkkld.kekylsltinfsa 71 
                 ++ll+Gp GtGKt++i  l +++  ++++  ++++++a
  EEA20089.1  79 HLLLYGPPGTGKTTTILALARRIYgSKNMRQMVLELNA 116
                 789***************77776646777777777766 PP

>> SRP54  SRP54-type protein, GTPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   7.2e-05     0.035       4      60 ..      80     141 ..      78     164 .. 0.67

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 7.2e-05
                 EEEEESTTSSHHHHHHHHHHHHHHT....TS-EEEEEESTSSTTHH.HHHHHHHHHTTEEEE CS
       SRP54   4 illvGlqGaGKTttlaKLaallkke....gkkvllvaaDtfRaaAv.eQLktlaeklgvpvi 60 
                 +ll G+ G+GKTtt+  La+++  +    ++ + l a D   +  v eQ+kt+a++ ++  +
  EEA20089.1  80 LLLYGPPGTGKTTTILALARRIYGSknmrQMVLELNASDDRGIDVVrEQIKTFASTKQIFSV 141
                 6899***************9764432222222235566665554433788888877776544 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.2    0.0003      0.15      24      43 ..      79      98 ..      55     184 .. 0.82
   2 ?   -1.6   0.0         3   1.4e+03     178     192 ..     188     202 ..     177     205 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.0003
  Mg_chelatase 24 nlllvGppGsGKtmlakrlp 43
                  +lll+GppG+GKt  + +l+
    EEA20089.1 79 HLLLYGPPGTGKTTTILALA 98
                  89**********98655543 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 3
  Mg_chelatase 178 ierYlsklsgplldR 192
                   i++Y++kls +ll R
    EEA20089.1 188 IANYTHKLSPALLSR 202
                   789*********999 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   0.00015     0.071       2      26 ..      81     105 ..      80     133 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 0.00015
  RNA_helicase   2 wlyGpsgeGKStlakeLakallkkl 26 
                   +lyGp+g+GK+t++  La+++ ++ 
    EEA20089.1  81 LLYGPPGTGKTTTILALARRIYGSK 105
                   79*****************999665 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   0.00022      0.11     104     156 ..      54     104 ..      38     132 .. 0.82
   2 ?   -3.0   0.0       6.2     3e+03      22      53 ..     211     242 ..     203     252 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00022
       T2SSE 104 tlddlgaeealkekiaevlrkavrerglilvsGgTgsGKttllyallkeinks 156
                 +ld+++ +++  ++i++++ +   +   +l+ G+ g+GKtt++ al   i  s
  EEA20089.1  54 SLDEVQGHQDILATINRFIDSH--RLPHLLLYGPPGTGKTTTILALARRIYGS 104
                 5677777777778888888887..66789**************9998887655 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 6.2
       T2SSE  22 pervkvrervdgielreveelekaalerlisr 53 
                   +v +r  vd++  +e  +++++a+e l++ 
  EEA20089.1 211 LKEVDIRSLVDKVIEAENVRIQPQAIESLVRL 242
                 55678888888888888888888888888765 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0    0.0013      0.62      42      70 ..      70     100 ..      52     121 .. 0.82
   2 ?    0.7   0.0      0.76   3.7e+02     103     133 ..     147     175 ..     123     194 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.0013
   IstB_IS21  42 sfiekke..nivllGpsGvGKshlaialgve 70 
                  fi+++    ++l Gp+G+GK+    al+++
  EEA20089.1  70 RFIDSHRlpHLLLYGPPGTGKTTTILALARR 100
                 467666533699**********999999875 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.76
   IstB_IS21 103 lkrllkvdllilDdlgllpldqaeaellfev 133
                  ++l +++l+ilD+    +     +  l ++
  EEA20089.1 147 ENSLGAFKLIILDEADAMTATA--QMALRRI 175
                 5678899******987665433..3334444 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   0.00022      0.11       8      83 ..      65     147 ..      62     196 .. 0.63

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00022
    ATPase_2   8 lkeleeilerepneiyfiYGpegsGKtaLlkeiienledkdkyviyyialreesiskldefieeeeekkklekal.......g 83 
                 l  +++ +++ + + +++YGp g GKt+ +  ++ +   ++  +  + +l+ ++   +d   e+ +   + ++ +        
  EEA20089.1  65 LATINRFIDSHRLPHLLLYGPPGTGKTTTILALARRIYGSKNMRQMVLELNASDDRGIDVVREQIKTFASTKQIFsvaapakE 147
                 5678888999999999*****************99997777777777777777777777763322222222222244344442 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.1    0.0024       1.2       1      23 [.      79     101 ..      79     113 .. 0.84
   2 ?    1.5   0.0      0.49   2.4e+02      79     122 ..     136     180 ..     116     222 .. 0.71

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.0024
                 EEEEE--TTSSHHHHHHHHHHHH CS
    NTPase_1   1 kvfiTGppGvGKtTlvkkvlell 23 
                 ++++ GppG+GKtT +  +++ +
  EEA20089.1  79 HLLLYGPPGTGKTTTILALARRI 101
                 67899**********99988876 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.49
                 HHHHHHHHHHHHHHHHHH-EEEE---STTGGG-HHHHH.HHHHHH CS
    NTPase_1  79 esfeelalealrkalseadviviDEiGkmElkskkfke.aveevL 122
                 +++ ++a++a +++l    +i++DE   m  +++   +  +e+  
  EEA20089.1 136 KQIFSVAAPAKENSLGAFKLIILDEADAMTATAQMALRrIMEKYT 180
                 5667788999999999999******99999888754440444433 PP

>> F_actin_cap_B  F-actin capping protein, beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00052      0.25      11      98 ..      20     117 ..      10     123 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00052
  F_actin_cap_B  11 lppkkveknlenlielvpdlaedllssvdqplkvakdkeegkeyllcdyNrdgdsYRSpwsnkYdpele..........dglvpseklrklEiean 96 
                       ++++++ +++++ +p  aed l  v++      d+ +g++ +l++ Nr  ds+R p+   Y p+ +            ++ s+++r++ +e+n
     EEA20089.1  20 FSSDNTNTKGKKIVADLPIGAEDNLPWVEKYRPSSLDEVQGHQDILATINRFIDSHRLPHLLLYGPPGTgktttilalaRRIYGSKNMRQMVLELN 115
                    55566666666777777777777788888888888899999***********************88776555555555569999******999988 PP

  F_actin_cap_B  97 ea 98 
                     +
     EEA20089.1 116 AS 117
                    75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       671  (0.0374254); expected 358.6 (0.02)
Passed bias filter:                      621  (0.0346366); expected 358.6 (0.02)
Passed Vit filter:                       111  (0.00619109); expected 17.9 (0.001)
Passed Fwd filter:                        37  (0.0020637); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              37  [number of targets reported over threshold]
# CPU time: 0.85u 0.36s 00:00:01.21 Elapsed: 00:00:00.58
# Mc/sec: 2050.07
//
Query:       EEA20090.1  [L=188]
Description: ARP2/3 complex subunit Arc18, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.2e-73  246.9   0.0    1.3e-73  246.7   0.0    1.0  1  P21-Arc    ARP2/3 complex ARPC3 (21 kDa) subunit
  ------ inclusion threshold ------
      0.023   14.8   0.1      0.042   13.9   0.1    1.4  1  Hormone_3  Pancreatic hormone peptide


Domain annotation for each model (and alignments):
>> P21-Arc  ARP2/3 complex ARPC3 (21 kDa) subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  246.7   0.0   1.5e-77   1.3e-73       1     174 []       1     188 []       1     188 [] 0.99

  Alignments for each domain:
  == domain 1  score: 246.7 bits;  conditional E-value: 1.5e-77
     P21-Arc   1 mpayhssfneeeevrlvgnlallplktkvrgpapka..............deeeediidealelFranvlfrnfeikgeaDrvLiYlilfisecLkklk 85 
                 mpayhs f +e+e  ++gn++llpl+t++rgpa+                ++e++d+ide+l+lFranvlfrnfeikg+aDr+LiY+ilf+secL k+k
  EEA20090.1   1 MPAYHSIFLDEAELPVIGNFPLLPLRTRTRGPAYVLpalppsesdldidpNSESYDCIDEILSLFRANVLFRNFEIKGPADRMLIYGILFLSECLGKVK 99 
                 9*********************************9999***********999*********************************************** PP

     P21-Arc  86 kstskeeaekelatlalenfaiPgdagfpLnslyekpkskeeadllrqYlkqlrqelalrllervyeddekpskwWlafakrkFmnksL 174
                 ++++ ++aek+l+++ale+faiPgda+fpLn+ +e+p+++++a++lrqYl+q+rqela+rll r+y  +e psk+Wl+fakrkFm+ksL
  EEA20090.1 100 PTMTARDAEKALINVALEQFAIPGDASFPLNQAFERPRDRQDAEQLRQYLSQVRQELAIRLLIRLYPGGEGPSKFWLSFAKRKFMGKSL 188
                 ******************************************************************9999*****************98 PP

>> Hormone_3  Pancreatic hormone peptide
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.1   4.7e-06     0.042       5      25 ..     134     154 ..     134     158 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 4.7e-06
                 XXXXTTS-HHHHHHHHHHHHH CS
   Hormone_3   5 erPgedaspEeLakYyaaLrh 25 
                 erP++   +E+L++Y++++r+
  EEA20090.1 134 ERPRDRQDAEQLRQYLSQVRQ 154
                 79*****************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (188 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       476  (0.0265492); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.36s 00:00:00.95 Elapsed: 00:00:00.56
# Mc/sec: 1006.99
//
Query:       EEA20091.1  [L=216]
Description: ARP2/3 complex subunit Arc18, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.4e-62  210.8   0.0    1.8e-62  210.4   0.0    1.1  1  P21-Arc    ARP2/3 complex ARPC3 (21 kDa) subunit
  ------ inclusion threshold ------
      0.028   14.5   0.1      0.051   13.6   0.1    1.4  1  Hormone_3  Pancreatic hormone peptide


Domain annotation for each model (and alignments):
>> P21-Arc  ARP2/3 complex ARPC3 (21 kDa) subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  210.4   0.0     2e-66   1.8e-62       1     159 [.       1     173 [.       1     177 [. 0.98

  Alignments for each domain:
  == domain 1  score: 210.4 bits;  conditional E-value: 2e-66
     P21-Arc   1 mpayhssfneeeevrlvgnlallplktkvrgpapka..............deeeediidealelFranvlfrnfeikgeaDrvLiYlilfisecLkklk 85 
                 mpayhs f +e+e  ++gn++llpl+t++rgpa+                ++e++d+ide+l+lFranvlfrnfeikg+aDr+LiY+ilf+secL k+k
  EEA20091.1   1 MPAYHSIFLDEAELPVIGNFPLLPLRTRTRGPAYVLpalppsesdldidpNSESYDCIDEILSLFRANVLFRNFEIKGPADRMLIYGILFLSECLGKVK 99 
                 9*********************************9999***********999*********************************************** PP

     P21-Arc  86 kstskeeaekelatlalenfaiPgdagfpLnslyekpkskeeadllrqYlkqlrqelalrllervyeddekpsk 159
                 ++++ ++aek+l+++ale+faiPgda+fpLn+ +e+p+++++a++lrqYl+q+rqela+rll r+y  +e psk
  EEA20091.1 100 PTMTARDAEKALINVALEQFAIPGDASFPLNQAFERPRDRQDAEQLRQYLSQVRQELAIRLLIRLYPGGEGPSK 173
                 ******************************************************************98888887 PP

>> Hormone_3  Pancreatic hormone peptide
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   5.7e-06     0.051       5      25 ..     134     154 ..     134     158 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 5.7e-06
                 XXXXTTS-HHHHHHHHHHHHH CS
   Hormone_3   5 erPgedaspEeLakYyaaLrh 25 
                 erP++   +E+L++Y++++r+
  EEA20091.1 134 ERPRDRQDAEQLRQYLSQVRQ 154
                 79*****************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (216 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       412  (0.0229795); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.34s 00:00:00.93 Elapsed: 00:00:00.54
# Mc/sec: 1206.25
//
Query:       EEA20092.1  [L=578]
Description: eukaryotic translation initiation factor 3, gamma subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   6.8e-122  406.3   0.2   8.5e-122  406.0   0.2    1.1  1  Gcd10p    Gcd10p family
  ------ inclusion threshold ------
       0.73   10.1   2.6       0.65   10.2   0.7    1.9  2  FF        FF domain


Domain annotation for each model (and alignments):
>> Gcd10p  Gcd10p family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  406.0   0.2  9.5e-126  8.5e-122       2     300 .]       5     378 ..       4     378 .. 0.98

  Alignments for each domain:
  == domain 1  score: 406.0 bits;  conditional E-value: 9.5e-126
      Gcd10p   2 IkpndhvllkLpsenlkivqvkpnttisLgKfgsfplnliigrpygltfeildkreeeeksrlrvvpaaeleaeslaeeeaeeeeeeee.......... 90 
                 ++p+++v+++L s+ +k+v+ +pntti LgK+gsf++n+i+grp++lt+e+ +++ee+  ++lrvvpaael+ae+l +e ++e++ + e          
  EEA20092.1   5 VQPDQWVAIRLSSDMYKLVKATPNTTILLGKYGSFYTNQILGRPFHLTYELSNESEED-GYSLRVVPAAELHAEALISEGSAEADGMIEeadpgnteqq 102
                 89**************************************************999765.556******************999888777999******* PP

      Gcd10p  91 .arsnreiiddgarQkLtkeeIeeLKkegtsagkeiIaklleshtafdqKTaFSqeKYlkrKkkKYlkrftvlpldvsllleyllekkdaqkilelree 188
                   r+nr+i+ddg++Q+Lt+eeIeeLK++ t+agkeiI+kllesh+++d+KTaFS++KY++rK+kKYlkrft+ pldv+ l+ey+le+k+a++i+elr+e
  EEA20092.1 103 pIRTNRDINDDGSAQTLTWEEIEELKQNATGAGKEIIDKLLESHSTIDKKTAFSLAKYKLRKEKKYLKRFTIVPLDVNILTEYMLEQKEASRIMELRQE 201
                 *************************************************************************************************** PP

      Gcd10p 189 tlglllslanvhagg.........ryLvvDdtgGLlvaalaeRmgi..................................................... 225
                 ++gll++++nvh++g         ryLvvDdtgGL+vaa+aeRmgi                                                     
  EEA20092.1 202 SIGLLGCWGNVHHSGnlenmdpsgRYLVVDDTGGLVVAAMAERMGIlystqddednedvddesglngkseettaapgqankkrtsgaqgakpqnqqrir 300
                 **************************************************************************************************9 PP

      Gcd10p 226 f.essakegtivliheneqpnlsllkyfnydaae..pehplkkhlktlswlqllepeedetyeeepeevseeelaelk 300
                   +++ak++ti++ih+++qpnlsllkyf+y+a+e  ++hpl +hlk+ +wlq+l+pe+d+ y+e+peev++++l++ k
  EEA20092.1 301 KqPMTAKQNTITVIHPHSQPNLSLLKYFGYEAEEpdESHPLFDHLKMATWLQILDPEADNIYSEKPEEVDDATLKTYK 378
                 559***************************9999999***********************************999876 PP

>> FF  FF domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       1.2     1e+04      20      27 ..     119     126 ..     117     127 .. 0.80
   2 ?   10.2   0.7   7.2e-05      0.65       8      37 ..     141     170 ..     140     173 .. 0.95

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 1.2
                 SSHHHHHH CS
          FF  20 stWseikk 27 
                  tW+ei++
  EEA20092.1 119 LTWEEIEE 126
                 69***986 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 7.2e-05
                 HHHHHCSSS-TTSSHHHHHHHCTTSCCCHH CS
          FF   8 eLLkehkeitpkstWseikkilenDpRYla 37 
                 +LL++h  i++k+ +s +k +l++++ Yl+
  EEA20092.1 141 KLLESHSTIDKKTAFSLAKYKLRKEKKYLK 170
                 69**************************75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (578 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       677  (0.0377601); expected 358.6 (0.02)
Passed bias filter:                      477  (0.0266049); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.77u 0.35s 00:00:01.12 Elapsed: 00:00:00.55
# Mc/sec: 3149.97
//
Query:       EEA20093.1  [L=868]
Description: DUF455 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.5e-20   72.2   0.0    6.9e-20   71.2   0.0    1.5  1  MINDY_DUB  MINDY deubiquitinase
  ------ inclusion threshold ------
       0.46    9.5   9.7       0.89    8.6   9.7    1.4  1  Roughex    Drosophila roughex protein


Domain annotation for each model (and alignments):
>> MINDY_DUB  MINDY deubiquitinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.2   0.0   7.7e-24   6.9e-20       1     113 [.     397     520 ..     397     523 .. 0.87

  Alignments for each domain:
  == domain 1  score: 71.2 bits;  conditional E-value: 7.7e-24
   MINDY_DUB   1 vNvLlLsgk.......iellpedreevsleeLlelladilldnnplnqeenlsellelLpklqtgldvnprF.....dgidsFektselalFdllnipL 87 
                 vN L+++ +       ++ l ++re++sl+ L+++l+d+l++ ++ ++  ++++l ++L++l+tg++vnpr+     + + sF +t++++l+d +++pL
  EEA20093.1 397 VNGLIMRSDrkaqppiVRAL-QTRENISLGLLIQALFDELVTYSN-EELPDIEALSRFLTMLHTGMNVNPRLtlgspTALGSFFETKDIQLYDSFKVPL 493
                 68888888888888877776.99*******************998.677789********************888887777****************** PP

   MINDY_DUB  88 vHGwlvdpqdaeaaeal.saksYneav 113
                 vHGw+++p++  +a+ +  a+ Y++++
  EEA20093.1 494 VHGWIAEPKSGVHASMVrVAQYYEDIQ 520
                 ********7777777773666677664 PP

>> Roughex  Drosophila roughex protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   9.7   9.9e-05      0.89     279     320 ..     681     736 ..     656     785 .. 0.49

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 9.9e-05
     Roughex 279 keedkd.............eqeqqaeqeeqaqqqaeeapvs.sdistalketnppa 320
                 ++ed+d             +q+qq +q++q+qqq++    s   +sta ++t p  
  EEA20093.1 681 EQEDADyayalslqfqeeaQQQQQQQQQQQQQQQPNSRSFStRAASTAARNTGPAH 736
                 23444455555555532212333334444455555544333145677777777543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (868 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1986  (0.11077); expected 358.6 (0.02)
Passed bias filter:                      609  (0.0339673); expected 358.6 (0.02)
Passed Vit filter:                        87  (0.00485247); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 1.16u 0.39s 00:00:01.54 Elapsed: 00:00:00.57
# Mc/sec: 4597.61
//
Query:       EEA20094.1  [L=800]
Description: heat shock transcription factor Hsf1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      9e-28   96.7   0.2      2e-27   95.6   0.2    1.6  1  HSF_DNA-bind    HSF-type DNA-binding
     0.0069   16.4   1.7        0.3   11.1   0.1    2.5  2  TMF_DNA_bd      TATA element modulatory factor 1 DNA binding
  ------ inclusion threshold ------
      0.013   16.0   0.0      0.031   14.8   0.0    1.6  1  Ets             Ets-domain
      0.048   13.4   0.2       0.28   10.9   0.1    2.3  2  Pex19           Pex19 protein family
      0.079   13.7   0.2      0.079   13.7   0.2    2.7  2  JHY             Jhy protein
      0.092   12.8   2.4        4.5    7.3   0.2    2.3  2  CENP-F_leu_zip  Leucine-rich repeats of kinetochore protein C
       0.11   11.9   1.5        7.6    5.8   0.3    2.7  2  Aminopep        Putative aminopeptidase
       0.11   13.0   1.6       0.34   11.4   0.2    2.3  2  APG6_N          Apg6 coiled-coil region
       0.12   13.1   0.9        1.1    9.9   0.2    2.7  2  DUF4404         Domain of unknown function (DUF4404)
       0.19   11.9   2.5       0.39   10.8   0.9    2.1  2  MRP-L28         Mitochondrial ribosomal protein L28
       0.26   11.1   0.6          1    9.2   0.6    2.0  1  TRAF_BIRC3_bd   TNF receptor-associated factor BIRC3 binding 


Domain annotation for each model (and alignments):
>> HSF_DNA-bind  HSF-type DNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.6   0.2   1.2e-30     2e-27       1      95 [.     148     250 ..     148     251 .. 0.87

  Alignments for each domain:
  == domain 1  score: 95.6 bits;  conditional E-value: 1.2e-30
                   HHHHHHHHHCT...TTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE.....---SSB....TTB--TTSEEEEESS--XX CS
  HSF_DNA-bind   1 FlkkLyklled...eelisWsedgksfvvkdkeefakevlpkyfkhsnfssFvrqLnlYgFrk.....vkrkee....kkkkkskvweFshenFkrg 85 
                   F++kL ++l++   +++i+Ws+dg+sf+v d++efa++++p++fkh++++sFvrqLn+YgF+k          +    +++k+++ +e+++++Fkrg
    EEA20094.1 148 FVQKLRSFLDEpqyADFIRWSDDGNSFIVLDEDEFARRLIPELFKHNKYASFVRQLNMYGFHKkvglsD----NsmraSERKNKSPSEYANPYFKRG 240
                   9********88667888**********************************************766432....13444666666777********** PP

                   XXXXXXXXXX CS
  HSF_DNA-bind  86 kpelLkkikr 95 
                   +p+lL  i++
    EEA20094.1 241 HPDLLWLIQK 250
                   *****99986 PP

>> TMF_DNA_bd  TATA element modulatory factor 1 DNA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.1   0.1   0.00018       0.3      10      65 ..     307     361 ..     303     368 .. 0.91
   2 ?    3.8   0.2     0.035        57      41      70 ..     579     608 ..     576     611 .. 0.64

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00018
  TMF_DNA_bd  10 KDeqIaqLmeEGekLskkelklnntikkLrkknkelekeikelkkkleklekelee 65 
                 KD q+a +  E++  + +++  + ti+kLr + ++l  + ++ +++ ++ e +++ 
  EEA20094.1 307 KD-QLAGVYRELQTIRQQQQIISSTISKLRREHEQLYAQAANFQEQHSRHENSINA 361
                 55.8899999**************************************99999875 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.035
  TMF_DNA_bd  41 knkelekeikelkkkleklekeleeleerl 70 
                 +++++ +ei++l k  +++++++++l+++l
  EEA20094.1 579 QLANTRNEIDNLMKMQAEQDRSVQNLTNLL 608
                 555666666666666666666666666655 PP

>> Ets  Ets-domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.8   0.0   1.9e-05     0.031       6      41 ..     152     186 ..     148     213 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 1.9e-05
         Ets   6 llelLedpskssiiaWtdkeegeFklvdpeevarlW 41 
                 l++ L++p++ ++i+W d+ + +F ++d++e+ar+ 
  EEA20094.1 152 LRSFLDEPQYADFIRWSDD-GNSFIVLDEDEFARRL 186
                 7889*************88.*************975 PP

>> Pex19  Pex19 protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.1   0.00017      0.28      67     136 ..     321     393 ..     264     393 .. 0.81
   2 ?   -1.2   0.0      0.89   1.5e+03       9      39 ..     582     610 ..     574     637 .. 0.61

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00017
       Pex19  67 esfqdiikkTlerLkesgdkvdaaa...eseeknsddllaqlLkqLeagadvegeggeeg.edlekmllgmmeq 136
                  + q+ii++T+++L+   +++ a+a   +++++  ++ ++++L  L     + + +g++g +++ + ++g+++q
  EEA20094.1 321 RQQQQIISSTISKLRREHEQLYAQAanfQEQHSRHENSINAILTFLATV-YNRSLQGHDGpQNIANSFSGIISQ 393
                 56799******************99999999999999****99999444.444455555568999999998876 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.89
       Pex19   9 qlekemeelmkelkeeeeeeaeedfeellkq 39 
                 ++++e+++lmk +  +e++   ++ ++ll+ 
  EEA20094.1 582 NTRNEIDNLMKMQ--AEQDRSVQNLTNLLQP 610
                 4455666666665..3333344444444443 PP

>> JHY  Jhy protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.2   4.9e-05     0.079      21     130 ..     190     349 ..     178     351 .. 0.87
   2 ?   -1.9   1.1       3.1   5.1e+03      84     114 ..     445     475 ..     428     506 .. 0.53

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 4.9e-05
         JHY  21 aerqkeYAkqvreqnkkeksanikadkknekkaenkdalsrkkaleYAKn........IpkPkkaakpketsseksakssleekkanpekekkvte... 108
                 +++ ++YA  vr+ n+   ++++  ++++   +e+k++++ + a  Y K+        I+kPk+a+ + ++     + ++++++ +++++ +++ +   
  EEA20094.1 190 LFKHNKYASFVRQLNMYGFHKKVGLSDNSMRASERKNKSPSEYANPYFKRghpdllwlIQKPKNAPGQGSK---GGKGAKIKTEDGDEHDADDLVDdig 285
                 78999***********9998888887888888888888888889999997667777779****99999888...6888999999999999999888999 PP

         JHY 109 ..........................................lselekLkqrHekekqavaalr 130
                                                            s + kL++ He+  +++a+++
  EEA20094.1 286 rderprlggqlaitnghdvmpkdqlagvyrelqtirqqqqiiSSTISKLRREHEQLYAQAANFQ 349
                 99999999999999999999999999999999999999999999***********999999986 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 3.1
         JHY  84 sseksakssleekkanpekekkvtelselek 114
                 s ++s+ + + ++k  +++ +++  ++e++ 
  EEA20094.1 445 SPAASNYDTVSNRKYSRQSSTPSHTIEEVQD 475
                 3344444444444444444444444444443 PP

>> CENP-F_leu_zip  Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   0.2    0.0027       4.5      52      97 ..     308     353 ..     305     369 .. 0.81
   2 ?    4.9   0.1     0.015        25      71     102 ..     576     607 ..     574     612 .. 0.87

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0027
  CENP-F_leu_zip  52 aevetlkeeieelaeelreleldLvalrsekeeLekelqkkqervs 97 
                      ++ ++  e+++++++ + +++ +++lr+e e+L  +  + qe+ s
      EEA20094.1 308 DQLAGVYRELQTIRQQQQIISSTISKLRREHEQLYAQAANFQEQHS 353
                     5667778899999999999999999999999999998888888755 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.015
  CENP-F_leu_zip  71 leldLvalrsekeeLekelqkkqervseLesl 102
                      +++L+++r+e ++L+k+  ++ + v++L +l
      EEA20094.1 576 YTAQLANTRNEIDNLMKMQAEQDRSVQNLTNL 607
                     6789*************999999999999765 PP

>> Aminopep  Putative aminopeptidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.018        29     168     223 ..     101     158 ..      96     173 .. 0.79
   2 ?    5.8   0.3    0.0047       7.6     198     251 ..     315     368 ..     303     388 .. 0.51

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.018
    Aminopep 168 dtafnEsfAtaVeregverwlaaegsaaareeaa..aekarreqfralvkatrerLea 223
                 + af  s At V ++g   w ++ ++ ++r+ +a  +++a+r+q   +v+++r+ L++
  EEA20094.1 101 NRAFEQSSATSVPESGGDGWGESIAELEQRALIAkrEAQAKRKQIPPFVQKLRSFLDE 158
                 6799*****************9988887766554114567889999999999988765 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0047
    Aminopep 198 eeaaaekarreqfralvkatrerLealYasdlsaeekraakaeileelraeyae 251
                 +e ++ +++++  ++ ++++r++ e+lYa++++ +e++++ ++ ++++ +  a+
  EEA20094.1 315 RELQTIRQQQQIISSTISKLRREHEQLYAQAANFQEQHSRHENSINAILTFLAT 368
                 233444444444455555555555555555554444444444444444333333 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.2   0.00021      0.34      70     118 ..     310     358 ..     299     370 .. 0.57
   2 ?   -1.1   0.1       1.6   2.6e+03      16      36 ..     578     598 ..     574     610 .. 0.50

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00021
      APG6_N  70 Lkelekereeleaelaaleeelealeeeeerfwreynelqlelleleee 118
                 L+ + +e + ++++ + ++++ ++l +e e+   +  ++q +++++e+ 
  EEA20094.1 310 LAGVYRELQTIRQQQQIISSTISKLRREHEQLYAQAANFQEQHSRHENS 358
                 4444445555555555555555555555555555555555555555544 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 1.6
      APG6_N  16 kqleqaekerdaYeeflkklk 36 
                  ql+++++e+d++++  ++ +
  EEA20094.1 578 AQLANTRNEIDNLMKMQAEQD 598
                 455555555555544443333 PP

>> DUF4404  Domain of unknown function (DUF4404)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.2    0.0007       1.1       9      79 ..     293     367 ..     290     369 .. 0.88
   2 ?   -0.3   0.0         1   1.7e+03      22      48 ..     576     602 ..     569     611 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.0007
     DUF4404   9 heeLeqnesldeetralLeslaedieellaeedaaaeeee....laerlneaverFeeeHPklagvlreildsLa 79 
                   +L+ ++  d   +++L+ + ++++ + ++++  +++ +      e+l  ++++F e+H + ++ ++ il  La
  EEA20094.1 293 GGQLAITNGHDVMPKDQLAGVYRELQTIRQQQQIISSTISklrrEHEQLYAQAANFQEQHSRHENSINAILTFLA 367
                 5678888888889999**********999999999998878887889999*********************9998 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 1
     DUF4404  22 tralLeslaedieellaeedaaaeeee 48 
                   a+L++ +++i +l++ +++++ + +
  EEA20094.1 576 YTAQLANTRNEIDNLMKMQAEQDRSVQ 602
                 578999999999999998888776644 PP

>> MRP-L28  Mitochondrial ribosomal protein L28
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0      0.86   1.4e+03      69      91 ..     123     145 ..     100     161 .. 0.79
   2 ?   10.8   0.9   0.00024      0.39      92     128 ..     314     350 ..     305     354 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.86
                 -HHHHHHHHHHHHHHHHHHHHHH CS
     MRP-L28  69 skeelerrallekqwaryrqqek 91 
                 s +ele+ral+ k+ a+ ++++ 
  EEA20094.1 123 SIAELEQRALIAKREAQAKRKQI 145
                 67889999999999888888765 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00024
                 HHHHHHHHHHHHHHHHHHHHHHHH-TTTCTTCS-XXT CS
     MRP-L28  92 ekdeqlirqqleaqeealeeLkkvseeLYeaAvkrde 128
                  ++ q+irqq + +  ++++L+++ e+LY++A + +e
  EEA20094.1 314 YRELQTIRQQQQIISSTISKLRREHEQLYAQAANFQE 350
                 5789*************************99976555 PP

>> TRAF_BIRC3_bd  TNF receptor-associated factor BIRC3 binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.6   0.00062         1      14      51 ..     325     362 ..     313     367 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00062
  TRAF_BIRC3_bd  14 atFEnIVsVLnrEverssttieaverqrrldqekieaL 51 
                    ++    +s L rE e+  ++++++++q+   ++ i+a+
     EEA20094.1 325 QIISSTISKLRREHEQLYAQAANFQEQHSRHENSINAI 362
                    555567899*************************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (800 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1113  (0.0620782); expected 358.6 (0.02)
Passed bias filter:                      723  (0.0403257); expected 358.6 (0.02)
Passed Vit filter:                        95  (0.00529868); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.93u 0.41s 00:00:01.34 Elapsed: 00:00:00.58
# Mc/sec: 4131.21
//
Query:       EEA20095.1  [L=357]
Description: aldo-keto reductase (AKR), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      2e-11   43.6   0.0      7e-11   41.9   0.0    1.8  2  Aldo_ket_red  Aldo/keto reductase family


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.9   0.0   3.9e-15     7e-11      14     184 ..      74     264 ..      65     274 .. 0.76
   2 ?   -3.3   0.0      0.22     4e+03      57      70 ..     318     331 ..     288     345 .. 0.68

  Alignments for each domain:
  == domain 1  score: 41.9 bits;  conditional E-value: 3.9e-15
                   TS-HHHHHHHHHHHHHTT--EEE--TT...-TTTHHHHHHHHHHHH-TTTGGG-EEEEEE....................--SSSTTSSSS-HHHHH CS
  Aldo_ket_red  14 eiskeealellrraleaGinffDtAev...YgkgqseellGealkksrkkreeviiatKv....................dlrdaeiksglskenir 87 
                   +++k+ ++el+ +al+ G++++DtA     Y++    + + +a+++  +kre++ i tK                     d  +a+i+s+l+  +  
    EEA20095.1  74 AWKKDRSAELVYTALKTGFRAVDTAAQpkhYREDLVGDGVRRAIAEGIVKREDLYIQTKYtpvsgqnphdmpydgslsitDQVKASIHSSLQNFR-- 168
                   6889*********************995556555555555558888**************88885555444433333222222222222222222.. PP

                   HHHHHHHHHHT-S-EEEEEE-S--TTS-.HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHH..HHTTT--EEEEE-B-BTT-HHHHTTHHHHHHHT CS
  Aldo_ket_red  88 esleeslkrLgtdyvDllllHrpdpslpsieevldaleelvkeGkiraiGvSnfsveqleka..kkkkkvkivavqveynllreleeegllelckkk 182
                      ++ l   +  y+D l lH p p+ ++  e++ a e +v    i ++G+Sn +   l+++  + + k+k+++vq+++    e+ + +l+++++++
    EEA20095.1 169 -IAKDDLNAVNGTYIDTLVLHSPLPTIVQTIEAWVAAESFVP-DVIHNLGISNCPLPVLKALctSPEIKIKPAVVQNRFYAD-EDYDVELRSFAREN 262
                   .234455666788****************************9.6*****************98888888999*****99766.77777888888777 PP

                   T- CS
  Aldo_ket_red 183 gv 184
                   ++
    EEA20095.1 263 DI 264
                   66 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 0.22
                   -TTTGGG-EEEEEE CS
  Aldo_ket_red  57 srkkreeviiatKv 70 
                   + ++ e++++++Kv
    EEA20095.1 318 EVHMAEDLRLSSKV 331
                   55677888888888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (357 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       341  (0.0190195); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.48
# Mc/sec: 2237.99
//
Query:       EEA20096.1  [L=584]
Description: extracellular lipase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.4e-87  294.7   0.0    1.9e-87  294.3   0.0    1.1  1  COesterase     Carboxylesterase family
    1.6e-07   31.4   0.0    3.6e-06   27.0   0.1    2.6  2  Abhydrolase_3  alpha/beta hydrolase fold
     0.0019   17.7   0.2     0.0036   16.8   0.2    1.4  1  Peptidase_S9   Prolyl oligopeptidase family


Domain annotation for each model (and alignments):
>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  294.3   0.0   3.2e-91   1.9e-87       3     497 ..      40     555 ..      38     568 .. 0.84

  Alignments for each domain:
  == domain 1  score: 294.3 bits;  conditional E-value: 3.2e-91
                 SEEEETTEEEEEEEEEESTCSEEEEEEEEESSB---GGGTTS--BE.----SSEEECBS---BESEECSSSSSCGHHCHHHBES---EEEEEEESSSSS CS
  COesterase   3 pvvetslGkvrGkrvklksekevdaFlGiPYAepPvgelRFkkPep.aepwtgvrdAtkfspaCpqnaeksekeekeleawvsEDCLyLnvytPkekke 100
                 p+v++++G   G  ++  +    d FlG+PY ++P+gelR + P+  +e+w g+r+At++sp+C+   + +        + +sEDCL++nv  P++   
  EEA20096.1  40 PTVTLKNGSYYGVHNSYYN---QDFFLGMPYTQAPLGELRLQVPQSlNETWAGTRNATQYSPECIGYGSDQWVLG----NDISEDCLTVNVVRPSN-IA 130
                 6788888888888888665...59**********************9******************9885433322....239************98.58 PP

                 TTSSEEEEEEE--STTTS-BGCG..S-THHHHHHH.....TSEEEEE----HHHHH-B-SSTTSBS..-HHHHHHHHHHHHHHHHGGGGTEEEEEEEEE CS
  COesterase 101 akkklPVlVwihGggfqtgsase..ydgsaLaaeg.....nvivVtinYRlGvlGFlstgdeeapG..NvGllDqvlALrWVkenIasFGGdpervtlf 190
                 a+ klPV++wihGggf +g +++  y++s+L+++       +i V++nYRl  +GFl  ++ +a G  N+G+ Dq+lAL+WV+enIa+FGGdp++vt+ 
  EEA20096.1 131 ADVKLPVVFWIHGGGFFEGGSRDprYNQSFLVQRSveigkPIIGVSVNYRLSGWGFLWGEEVAAAGvtNLGIRDQRLALHWVQENIAAFGGDPSKVTIH 229
                 99999****************9899*********9999999*****************9997777677******************************* PP

                 EETHHHHHHHHHHHSGGGT..TSBSEEEEES--TTSTTTSBSH..HHHHHHHHHHHTTS-CSSHHHHHHHHHCS-HHHHHHCCGGSSSSSSTTC-SSS- CS
  COesterase 191 GesAGaasvsllllsplsr..glfkraIlqSGsalspwaiqkk..arkrakklakkvgckassskelveclrsksaeelldaqekaleasssklvsfaP 285
                 GesAG+asv  +l+    r  glf+  I++SG +++ + + +      + +++ k +gc  ss+++++ clr+ ++e+l +  ++     s+   s + 
  EEA20096.1 230 GESAGGASVGTHLIAYGGRddGLFRASIAESGGPTALFYYVNAsaWEPNYQNIVKLAGC--SSASDTLACLRTIPTEQLSAIFNS-----SDVTASGGV 321
                 ***************8777679**********998888887777578899*********..88889*****************88.....788889999 PP

                 B--SSSSSS-HHHHHHCGC..CSEEEEEEETTTTHHHHCCHSTTTSSSSHHHHHHHHHHHHHHHHHHHCC..HHHHHHHHHHHHSTTTSSTCHHHHHHH CS
  COesterase 286 vvdgdflpekPeellkseg..kvplliGvnkdegllflaylldkeksvkkkeeklsesllkdelyleaek..keelseaikeeytdeadrddaeksrka 380
                 v+dgd++ e+  +l k+ +   vp+liG+n+deg+ f     +++++ k++    +   l++e++ + +k  +++ s  i +    ++   ++  ++++
  EEA20096.1 322 VIDGDIVAESATTLTKNGNfvRVPVLIGTNSDEGTAFGIPGINTTEEFKESLLYRTP-SLTKEVMDKIAKlyPDDPSLGIPSTLKGRPPPGSPFGRQWK 419
                 9*******99999999977******************99777764333333332222.22333333333355444455555555555555555555555 PP

                 .HHHHHHHHHTHHHHHHHHHHHHHTT-SEEEEEEE--STTSSSTTTGSSBTTTTHHHHTTGGGTSGCS..........S-HHHHHHHHHHHHHHHHHHH CS
  COesterase 381 .llelltdvlfkapvlrtaklhasrgspvYlYsfdyrnssskkpkwmgvvhgdeleyvfglpllekee..........ftkedeklsrkmmtywtnFak 468
                   +++ +d +++++ + +++++a++g p+Y Y+fd     +   +++g++h +e+ +vfg+   + +e          + +   +l+  m+t w +F+ 
  EEA20096.1 420 rSAAYGGDLTMHTGRRIATEAWARYGVPAYSYHFDVLV--NGVSEYIGSTHFQEIAFVFGNTAGQGYEnavsvnpfanEPATFDELASIMSTAWISFVH 516
                 0556668***************************9988..334689********************999*****9653222245799************ PP

                 HSSTTS..........TTSS----B.TTTBEEEEESSSS CS
  COesterase 469 tgnPnk..........eeeekWpkytkeeekylkinlkp 497
                   +Pn+          +e  +Wp y  ++   + +n + 
  EEA20096.1 517 DLDPNSnafsskkginKEGLRWPVYGRKNPANIAFNVNV 555
                 *************99999999****88888877777665 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.0   0.1     6e-10   3.6e-06       1      82 [.     138     235 ..     138     244 .. 0.75
   2 ?   -1.7   0.0      0.37   2.2e+03     116     145 ..     365     393 ..     325     401 .. 0.67

  Alignments for each domain:
  == domain 1  score: 27.0 bits;  conditional E-value: 6e-10
                    EEEE--STTTS--TTTT...HHHHHHHHHHHT..SEEEEEE---...........TTTS-TTHHHHHHHHHHHHHHHTHHHHTETTCEEEEEEETH CS
  Abhydrolase_3   1 lvyfHGGGfvlgsldth...dalcrelakelg..avvvsvdYrl...........APehpfPaavedalaalrwlaeqawelgadpsrivlaGdSa 80 
                    ++++HGGGf  g+++ +   ++++ + + e+g  ++ vsv+Yrl           A        + d   al+w++e+ +++g dps++++ G+Sa
     EEA20096.1 138 VFWIHGGGFFEGGSRDPrynQSFLVQRSVEIGkpIIGVSVNYRLsgwgflwgeevAAAGVTNLGIRDQRLALHWVQENIAAFGGDPSKVTIHGESA 233
                    689*******7766665566888888888887224558*****933333333333334444556899***********99**************** PP

                    HH CS
  Abhydrolase_3  81 GG 82 
                    GG
     EEA20096.1 234 GG 235
                    *9 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.37
                    TSHHHHHCHHTTTSSSSCHHHHHHHHHHHS CS
  Abhydrolase_3 116 esesikkaeeladgplltraaldlfwrlyl 145
                    ++e++ k++ l+++p lt++ +d +++ly 
     EEA20096.1 365 TTEEF-KESLLYRTPSLTKEVMDKIAKLYP 393
                    23444.233448889999*****9999995 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.2     6e-07    0.0036      29     116 ..     189     280 ..     172     291 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 6e-07
                   HCHHHHTTSGGGGHHHHHHHHHHHHHHHHTTS--GGGEEEEEETHHHHHHHHHH...H.H-GGG-SEEEEESE---CCCHHCSTTSTHHHCC CS
  Peptidase_S9  29 GeafhdagkrklgqnefdDfiaaaealakegyvdserlaitGgSyGGyltgaal...n.qrpdlFkaavaevpvvdvlrydsdtdllteeym 116
                   Ge+ + ag  +lg ++ +  + ++++ ++ +  d++++ i+G S+GG  +g+ l   + + + lF+a +ae +    l y+ + ++++++y+
    EEA20096.1 189 GEEVAAAGVTNLGIRDQRLALHWVQENIAAFGGDPSKVTIHGESAGGASVGTHLiayGgRDDGLFRASIAESGGPTALFYYVNASAWEPNYQ 280
                   67777777778888888888899999999999****************999755222447788**********9999999999887877776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (584 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       275  (0.0153383); expected 358.6 (0.02)
Passed bias filter:                      253  (0.0141112); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 3952.10
//
Query:       EEA20097.1  [L=288]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (288 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       421  (0.0234815); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.23s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2047.29
//
Query:       EEA20098.1  [L=137]
Description: hypothetical protein PMAA_039620 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-11   44.4   6.1    1.1e-11   44.3   6.1    1.0  1  Sugar_tr  Sugar (and other) transporter
    3.2e-05   23.0  14.1    4.6e-05   22.5  13.5    1.5  1  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.3   6.1   1.3e-15   1.1e-11      48     168 ..       2     132 ..       1     137 [] 0.85

  Alignments for each domain:
  == domain 1  score: 44.3 bits;  conditional E-value: 1.3e-15
                 HHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTT...SS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS...-SCCHH.HH CS
    Sugar_tr  48 sglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgk...nsvevlivgRvlvGigvGlasvlvPmyisEiA...pkklRg.al 139
                 ++ i +++l+Gai+G + +g+++d+++R+ +ll++++l+ +++++  +a +    n ++ +++ R ++G+gvG+++  +     E +    +++Rg ++
  EEA20098.1   2 QTRISNSLLIGAILGIIAFGYVTDMVSRRAGLLFTSFLVTVSTLMATLAVQVptsNLLWFFVIVRGICGFGVGGEYPPSAAAGLEESddfAPRYRGlIF 100
                 577899*******************************************966998999******************99988877766566677887257 PP

                 HHHHHHHHHHHHHHHHHHHHHHHTSS-...TT CS
    Sugar_tr 140 vslyqlaitfGilvaaifglglnktsn...ad 168
                 +s++ l++t+   +  i++l+  k sn   ++
  EEA20098.1 101 ISFTTLMVTLASPIQMIIYLICLKASNnnlSV 132
                 89999************999996666623443 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5  13.5   5.2e-09   4.6e-05      42     109 ..      10      83 ..       5     119 .. 0.85

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 5.2e-09
       MFS_1  42 algaavaslplGrlsdrfGrrr.vlllglllfalglllllfa.....sslw.lllvlrvlqGlgagalfpagaal 109
                  +ga+++++ +G+++d ++rr  +l++++l+++++ l++++a     s+l  +++++r ++G+g g+ +p +aa+
  EEA20098.1  10 LIGAILGIIAFGYVTDMVSRRAgLLFTSFLVTVST-LMATLAvqvptSNLLwFFVIVRGICGFGVGGEYPPSAAA 83 
                 6899*******************************.6666544567777666******************99885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (137 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       653  (0.0364214); expected 358.6 (0.02)
Passed bias filter:                      267  (0.0148921); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.41u 0.30s 00:00:00.71 Elapsed: 00:00:00.45
# Mc/sec: 913.44
//
Query:       EEA20099.1  [L=162]
Description: metabolite transport protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.3e-18   64.7   1.7    8.3e-18   64.5   1.7    1.0  1  Sugar_tr  Sugar (and other) transporter
    1.4e-07   30.8   9.8    1.8e-07   30.4   9.8    1.0  1  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.5   1.7   9.2e-22   8.3e-18     310     448 ..      10     143 ..       2     147 .. 0.91

  Alignments for each domain:
  == domain 1  score: 64.5 bits;  conditional E-value: 9.2e-22
                 HHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Sugar_tr 310 lvdrfGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfpi 408
                  +  +GRR++ ++G+ g+ i+ +i+g  ++ + +++     +++v++ l  a+  +g+g ++ +++sE fp+++R+ ++++++a   +   + + +f+ 
  EEA20099.1  10 GSNVVGRRYTGIIGFGGYVILGFIIG-GTYSQLSEH---IAAFVVLYGLLQAFGHMGPGVTIGLISSEAFPTAMRGMGYSVSTAFGRTGAAIGTECFTP 104
                 57789********************9.999999997...666777777888999********************************************* PP

                 HHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCC CS
    Sugar_tr 409 iteaigggyvflvfaglavlfiifvfffvpetkgrtleei 448
                 + +a g+  +f++ +g+ vl++ +v++f+pe   + lee 
  EEA20099.1 105 LEQAAGKSSIFYLAGGVGVLGM-IVYWFLPESGDLNLEEE 143
                 ******9999999999999876.689*****999999985 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.4   9.8     2e-11   1.8e-07      58     177 ..      13     137 ..       9     152 .. 0.83

  Alignments for each domain:
  == domain 1  score: 30.4 bits;  conditional E-value: 2e-11
       MFS_1  58 rfGrrrvlllglllfalglllll..fa...sslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgW 150
                  +Grr + ++g+ ++++ ++++   ++    ++  ++++  +lq++g  +   +++ + ++ fp   rg+++++ +a+   Ga++g      l +++g 
  EEA20099.1  13 VVGRRYTGIIGFGGYVILGFIIGgtYSqlsEHIAaFVVLYGLLQAFGHMGPGVTIGLISSEAFPTAMRGMGYSVSTAFGRTGAAIGTECFTPLEQAAGK 111
                 589***************666665763455667777888888999999777888888999999999********************888888999**** PP

       MFS_1 151 ravfyilaivsllafvlfllllpeepp 177
                 +++fy++++v++l+++ ++++lpe+  
  EEA20099.1 112 SSIFYLAGGVGVLGMI-VYWFLPESGD 137
                 **************88.6888877654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (162 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       502  (0.0279993); expected 358.6 (0.02)
Passed bias filter:                      338  (0.0188521); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.39u 0.22s 00:00:00.61 Elapsed: 00:00:00.37
# Mc/sec: 1311.24
//
Query:       EEA20100.1  [L=594]
Description: R3H domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-10   40.9   1.1    2.1e-10   40.4   0.1    1.8  2  R3H       R3H domain
    2.9e-06   27.0   0.1    5.1e-06   26.2   0.1    1.4  1  RRM_1     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom
  ------ inclusion threshold ------
       0.22   11.6   0.3       0.34   11.0   0.3    1.2  1  CAS_C     Crk-Associated Substrate C-terminal domain


Domain annotation for each model (and alignments):
>> R3H  R3H domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.4   0.1   3.5e-14   2.1e-10       4      60 .]     294     352 ..     291     352 .. 0.88
   2 ?   -4.0   0.1       2.6   1.6e+04      44      52 ..     390     398 ..     388     399 .. 0.78

  Alignments for each domain:
  == domain 1  score: 40.4 bits;  conditional E-value: 3.5e-14
                 HHHHHHHHHHHH-S.--EEE---.--SHHHHHHHHHHHHSSEEEEEE--SS-SEEEEEE CS
         R3H   4 lrvekklaefvkdt.grslefpp.mssyeRriiHelaeaygleseSvGeepkRrvvvtk 60 
                 l+++ ++  f +d  ++ l fp+ +++ +Rr +H+la+++gl++ S+G +++R+v+v++
  EEA20100.1 294 LQFYSQMLLFKEDMgREALIFPSnLTPVQRRTVHTLAHNMGLSHASRGTGEQRQVHVFR 352
                 567777788887763589***************************************86 PP

  == domain 2  score: -4.0 bits;  conditional E-value: 2.6
                 EEEEE--SS CS
         R3H  44 eseSvGeep 52 
                 es+S+G +p
  EEA20100.1 390 ESRSEGPGP 398
                 688888887 PP

>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.2   0.1   8.5e-10   5.1e-06       1      70 []     148     218 ..     148     218 .. 0.95

  Alignments for each domain:
  == domain 1  score: 26.2 bits;  conditional E-value: 8.5e-10
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrelk 70 
                 ++++n+p+ v++e+L +l+ + +        +   +g  +g af +F+s e+ +  ++ ln+ +l+gr+l+
  EEA20100.1 148 IVIKNIPFAVKKEQLVQLMTEMNLPLPYAFNYHfDNGVFRGLAFANFTSAEETATVIDMLNHFELQGRKLR 218
                 79*******************99998888888889*********************************986 PP

>> CAS_C  Crk-Associated Substrate C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.3   5.6e-05      0.34      14      95 ..     225     300 ..     199     304 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 5.6e-05
       CAS_C  14 vhLqskeevekqqkellkklkekekleklikeskesleqeqevtkpvendlssetpkkalssekksklsskdkqllafyseq 95 
                   Lq++e++e++++e + +l+e+   ++ i+ s+ +++   + ++   +++  ++p+ ++++  k  ++ +d q l+fys+ 
  EEA20100.1 225 LPLQERERIEREKRERRGQLEEQ---HRPIAASQLQTQ---SSMSSLASHIPATSPSPVSQRGPKLDVDLNDSQTLQFYSQM 300
                 56888888888888888777777...555555554444...23333445666677777778899999999*********985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (594 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       467  (0.0260472); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.26s 00:00:00.86 Elapsed: 00:00:00.45
# Mc/sec: 3929.97
//
Query:       EEA20101.1  [L=417]
Description: hypothetical protein PMAA_039650 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (417 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       585  (0.0326287); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 2732.63
//
Query:       EEA20102.1  [L=139]
Description: histone H2A [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.1e-16   61.4   0.0    1.4e-16   61.1   0.0    1.1  1  Histone        Core histone H2A/H2B/H3/H4
    1.7e-12   46.8   0.0    3.4e-12   45.9   0.0    1.5  1  Histone_H2A_C  C-terminus of histone H2A
    3.5e-05   24.0   0.0    4.9e-05   23.5   0.0    1.2  1  CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) a


Domain annotation for each model (and alignments):
>> Histone  Core histone H2A/H2B/H3/H4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.1   0.0   2.3e-20   1.4e-16      51     131 .]      21     101 ..      14     101 .. 0.94

  Alignments for each domain:
  == domain 1  score: 61.1 bits;  conditional E-value: 2.3e-20
                 HHHHHHXXSXXSXHHHHHHHHHHHH.TTSSSXEEXHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTXSEEXHHHHHHHHHHT CS
     Histone  51 irkyqkstdlliqklpfaRvvreivksekedlrisaeavlalqealEallvelfeeAnllakhaKRvTitpkDiqlArrlr 131
                  +++ +++++ + ++p  Rv r +++++++++r+ a+a ++++++lE+l++e++e+A+++ak+ K ++itp+++qlA+r++
  EEA20102.1  21 GKTQKSHSAKAGLQFPCGRVKRFLKNNTQNKMRVGAKAAVYVTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGD 101
                 5677888999999******************************************************************75 PP

>> Histone_H2A_C  C-terminus of histone H2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.9   0.0   5.7e-16   3.4e-12       1      34 [.     102     134 ..     102     135 .. 0.97

  Alignments for each domain:
  == domain 1  score: 45.9 bits;  conditional E-value: 5.7e-16
  Histone_H2A_C   1 EELnkLLggVTIAqGGVLPnIhkvLLpkktkkkk 34 
                    EEL++L++ +TIA+GGVLP I+ +LL k ++kkk
     EEA20102.1 102 EELDTLIR-ATIAYGGVLPRINRALLLKVEQKKK 134
                    9*******.***********************98 PP

>> CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) and archaeal histone
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   0.0   8.1e-09   4.9e-05       2      65 .]      34      98 ..      33      98 .. 0.96

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 8.1e-09
                   XXXHHHHHHHHHCC.TTXS-B-HHHHHHHHHHHHHHHHHHHHHHHHHHCCTTSSCE-HHHHHHHH CS
  CBFD_NFYB_HMF  2 eLPiarvkkImksd.pdarkiakdAkeliaecveefieelaseAaeickkekrKtikaehiklAv 65
                   ++P  rvk+ +k+  ++  ++   A ++++ ++e    e+++ A   +k+ k K i++ h++lA+
     EEA20102.1 34 QFPCGRVKRFLKNNtQNKMRVGAKAAVYVTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAI 98
                   69************888888*******************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (139 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       388  (0.0216409); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.45
# Mc/sec: 931.09
//
Query:       EEA20103.1  [L=188]
Description: phosphate transporter (Pho88), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.6e-82  274.0   0.2      4e-82  273.9   0.2    1.0  1  Pho88     Phosphate transport (Pho88)


Domain annotation for each model (and alignments):
>> Pho88  Phosphate transport (Pho88)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  273.9   0.2   2.2e-86     4e-82       1     182 []       1     184 [.       1     184 [. 0.97

  Alignments for each domain:
  == domain 1  score: 273.9 bits;  conditional E-value: 2.2e-86
       Pho88   1 mnpqvtnlviilvlmqvskkidfedpevllyvRilYvvsqliillvylyikskikkknDlttlkyvepasplskeeeklvttTvkdYDlaelkkllksi 99 
                 m++qvtnlviil++mqvsk+i+fe+p+vll vR+lY+vs+++il++yly++ski kk+Dlttlkyvepa++ s+ee+++vttTv++YD ++l++l++s+
  EEA20103.1   1 MAAQVTNLVIILGMMQVSKRIPFENPDVLLGVRALYIVSNVLILGIYLYVQSKISKKKDLTTLKYVEPAPMGSGEEPRPVTTTVMEYDKQQLRQLMRSQ 99 
                 899************************************************************************************************ PP

       Pho88 100 lmgvammafmhlymkytnPLllQsimplknllesnlvkihllgkpaegdLkRPFkaaagllgaa..eaktdkksiekaekagkgg 182
                 lmgv+mma+mhly+kytnPLl+Qsi+p+k++lesnlvkih+lgkpa+gdL+RPFkaaag++g    e k+dk+sie+aek+++gg
  EEA20103.1 100 LMGVGMMAVMHLYFKYTNPLLIQSILPVKSALESNLVKIHVLGKPATGDLQRPFKAAAGFMGMGqgEIKSDKASIENAEKNWRGG 184
                 ************************************************************843356**************99875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (188 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1305.11
//
Query:       EEA20104.1  [L=337]
Description: glyceraldehyde 3-phosphate dehydrogenase GpdA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.7e-69  230.5   0.0      1e-68  229.9   0.0    1.3  1  Gp_dh_C       Glyceraldehyde 3-phosphate dehydrogenase, C-ter
    1.3e-37  128.2   1.2    3.9e-37  126.6   0.3    2.1  2  Gp_dh_N       Glyceraldehyde 3-phosphate dehydrogenase, NAD b
     0.0027   17.8   0.1     0.0096   16.0   0.0    2.0  2  DapB_N        Dihydrodipicolinate reductase, N-terminus
  ------ inclusion threshold ------
       0.14   13.0   0.1        1.2   10.0   0.0    2.2  2  GFO_IDH_MocA  Oxidoreductase family, NAD-binding Rossmann fol


Domain annotation for each model (and alignments):
>> Gp_dh_C  Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  229.9   0.0   2.3e-72     1e-68       1     158 []     156     313 ..     156     313 .. 1.00

  Alignments for each domain:
  == domain 1  score: 229.9 bits;  conditional E-value: 2.3e-72
                 HHHHHHHHHHHHEEEEEEEEEEEECTTTSBSSSS--.SSTTTTSBTTCSSEEEE-THHHHHHHHSGGGTTTEEEEEEEESSSSEEEEEEEEEESSTS-H CS
     Gp_dh_C   1 LaplakvlndkfgikkglmttvhaytndQkllDgpskkdlrraraaaeniiptstgaakavglVlpelkgkldglAvrVPtpnvsvvdlvvelekevtv 99 
                 Laplak++nd+ g+++glmtt+h+yt++Qk++Dgps kd+r +r+aa+niip+stgaakavg+V+p l+gkl+g+++rVPt nvsvvdl++++ek+v++
  EEA20104.1 156 LAPLAKIVNDNWGLVEGLMTTIHSYTATQKTVDGPSAKDWRGGRTAAQNIIPSSTGAAKAVGKVIPALNGKLTGMSMRVPTSNVSVVDLTCRTEKPVSY 254
                 8************************************************************************************************** PP

                 HHHHHHHHHHHHTTTTTTEEEEHSHHHGGGGTTGCSSEEEEGGGCEEETTTEEEEEEEE CS
     Gp_dh_C 100 eevnaalkeaaegalkgilsyteeelvssDlvgdphssifdaketivveenlvkvvawy 158
                 +e++a++k+ aeg+lkgi++yte+++vs+D++g+++ss+fdak++i++++n++k+v+wy
  EEA20104.1 255 DEIKATVKKYAEGELKGIMGYTEDDVVSTDMNGNSNSSVFDAKAGIALNSNFIKLVSWY 313
                 **********************************************************9 PP

>> Gp_dh_N  Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  126.6   0.3   8.7e-41   3.9e-37       2     100 ..       4     103 ..       3     104 .. 0.98
   2 ?   -0.4   0.0      0.33   1.5e+03      49      92 ..     286     328 ..     258     331 .. 0.74

  Alignments for each domain:
  == domain 1  score: 126.6 bits;  conditional E-value: 8.7e-41
                 EEEEESTSHHHHHHHHHHHHHTTCEEEEEE-.TS-HHHHHHHHHEETTTEC-SS-EEEETTEEEETTEEEEEE--SSGGGS-CHHHTSSEEEE-SSS-- CS
     Gp_dh_N   2 kvainGfGRIGrlvlralleekelevvaind.ltdletlayllkyDsvhgrfkgeveaeeealvvngkkikvlaekdpeelpwkelgvdlVvestGvft 99 
                 kv+inGfGRIGr+v+r ++e+++ evva+nd +++++++ay+lkyD+ hg+fkg++e+e+++l+vngk++k+++e+dp++++w+e+g+ ++vestGvft
  EEA20104.1   4 KVGINGFGRIGRIVFRNVIEHDDAEVVAVNDpFIETHYAAYMLKYDTQHGQFKGTIEVEGSDLIVNGKRVKFYQERDPANIKWSETGAAYIVESTGVFT 102
                 9******************************99*****************************************************************9 PP

                 S CS
     Gp_dh_N 100 d 100
                 +
  EEA20104.1 103 T 103
                 8 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.33
                 TEC-SS-EEEETTEEEETTEEEEEE--SSGGGS-CHHHTSSEEE CS
     Gp_dh_N  49 hgrfkgeveaeeealvvngkkikvlaekdpeelpwkelgvdlVv 92 
                  g+ +++v   ++ + +n + ik+++  d +e  ++   vdl+v
  EEA20104.1 286 NGNSNSSVFDAKAGIALNSNFIKLVSWYD-NEWGYSRRVVDLIV 328
                 45555666666888999999999999888.78888888888876 PP

>> DapB_N  Dihydrodipicolinate reductase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   2.1e-06    0.0096       1      34 [.       3      35 ..       3      68 .. 0.88
   2 ?   -1.6   0.0      0.63   2.8e+03      42      65 ..      87     110 ..      71     146 .. 0.63

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 2.1e-06
                EEEEEETTTSHHHHHHHHHHHHSTTEEEEEEEET CS
      DapB_N  1 ikvavvGasGrmGkevvkaveeaedlelvaavdr 34
                +kv+++G+ Gr+G+ v + v e++d+e+va+ d 
  EEA20104.1  3 TKVGINGF-GRIGRIVFRNVIEHDDAEVVAVNDP 35
                59******.********************99765 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.63
                 TBHHHHSSSS--S-BEBSSHHHHH CS
      DapB_N  42 kdagellglgklgvavtddleevl 65 
                 ++ g +  ++++gv++t++ +++ 
  EEA20104.1  87 SETGAAYIVESTGVFTTTEKASAH 110
                 445555555555555554433332 PP

>> GFO_IDH_MocA  Oxidoreductase family, NAD-binding Rossmann fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00026       1.2       2      37 ..       4      38 ..       3      54 .. 0.89
   2 ?   -0.0   0.0      0.33   1.5e+03      91     116 ..     248     271 ..     246     275 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00026
                  EEEEETTSHHHHHHHHHHHHTTTTEEEEEEECSSHH CS
  GFO_IDH_MocA  2 rvaiiGaGkigskhlrplnesqrleevvalldpdae 37
                  +v+i G+G+ig+  +r++ e+ +++evva+ dp  e
    EEA20104.1  4 KVGINGFGRIGRIVFRNVIEH-DDAEVVAVNDPFIE 38
                  79*******************.********998665 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 0.33
                   EESSS-SSHHHHHHHHHHHHHHTS-E CS
  GFO_IDH_MocA  91 lEKPlattveeakelvelaekkgklv 116
                    EKP+  +++e+k+ v++ ++ + + 
    EEA20104.1 248 TEKPV--SYDEIKATVKKYAEGELKG 271
                   59***..9999999999888766655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (337 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       617  (0.0344135); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.47
# Mc/sec: 2164.79
//
Query:       EEA20105.1  [L=780]
Description: histone deacetylase HdaA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   3.5e-105  350.8   0.7   4.6e-105  350.4   0.7    1.1  1  Arb2           Arb2 domain
    4.6e-85  285.8   0.0    6.3e-85  285.3   0.0    1.2  1  Hist_deacetyl  Histone deacetylase domain


Domain annotation for each model (and alignments):
>> Arb2  Arb2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  350.4   0.7  5.1e-109  4.6e-105       1     257 [.     507     763 ..     507     765 .. 0.99

  Alignments for each domain:
  == domain 1  score: 350.4 bits;  conditional E-value: 5.1e-109
                 -HHHHHHHHHHHHHHHHH--EE---TTSSS----GGCEEE-TTGGG-SCEEEEEEE--EEE--C-TTCS-B-CCC-EEE-TCHHHHHHHHCTT-EEEEE CS
        Arb2   1 rlhdviReaqakkLaekyklvkLpilreklsksfenqvlatpnieeakkllvivHdppellaqpdpvtnklelhnsvlvdsvkkyidWavkqkygviDv 99 
                 r+hd+iR++qa++L+++ykl++L+i+r+++sksfenqvla+ n+++a +l+vi+Hdppe+++ ++p+tnkle+hn++++d vk+yi Wa++++y+viDv
  EEA20105.1 507 RFHDIIRQYQAQQLYNNYKLTSLWIYRSSISKSFENQVLASANYDRAVPLIVIFHDPPEMMGVHHPITNKLEPHNCWMADVVKDYIAWATQRNYAVIDV 605
                 78************************************************************************************************* PP

                 EE----.......--SSSS-HHHHHHHHHHHHHHHHHTTTTSSS.SEEEEEEECCHHHHHHHHHHHS.--TTTEEEEEEEECTS-------SSSTHHHH CS
        Arb2 100 nipkliteeeeeeskeeeeeesaasesqelllylwdnyielfesaekifllGvGdaysgvvkLlser.dvrsrvkavinFvaekslravksevdeslsd 197
                 nipk++t+++ +  k+eee+ ++ s+++el+ ylwdnyie++e a++if++GvGday gv++Ll++r ++++rv++vi+Fvae+++rav+s ++++ls+
  EEA20105.1 606 NIPKYVTTDTPDVGKYEEEDADRPSQTEELAGYLWDNYIEPNE-ATHIFFIGVGDAYYGVANLLINRdSIYQRVNSVISFVAENPVRAVASPTQTWLSR 703
                 ******9999999******************************.8**********************99****************************** PP

                 HHHHTEEEEE-TT-CCGTT-..----GGG--EEE-SSSSHHHHHHHCHHHHHHHHHCHT- CS
        Arb2 198 WYkknSlvfvskkhsvWkkeeskkvrkryGrvlrsdkeglnemleehleevtefildkle 257
                 WYk+nSlvfvs++h vW++e+++k++kryGr+lrs+k+glneml +h+ ev ++i ++++
  EEA20105.1 704 WYKDNSLVFVSHTHGVWHNENRRKPSKRYGRLLRSPKTGLNEMLLHHKPEVLTWIDERVN 763
                 *******************************************************99986 PP

>> Hist_deacetyl  Histone deacetylase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  285.3   0.0     7e-89   6.3e-85       1     307 []     145     458 ..     145     458 .. 0.94

  Alignments for each domain:
  == domain 1  score: 285.3 bits;  conditional E-value: 7e-89
                    SCCGTHHHHHHHHHHHHT.THHHHCCE..............EE-----HHHHTTTS-HHHHHHHHCHHHHCHHT.TTHCCHHHCCTSTSSSSSTHC CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxx.............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Hist_deacetyl   1 hpenpkRlsaileslaesvglldelel.............liqpseatkeellkvHskeYlelleslsnelkkkeeakekeleeiasklldddtpv 83 
                    hpe+p+R+  i++++ ++ gl+++  +              i++++atkee++ vH++e+ +++++++n  +++       lee       d++++
     EEA20105.1 145 HPEDPRRIYYIYKEICRA-GLVEDPDIvatprmlapvplkRIDARNATKEEVELVHTDEHYQFVSDTQNLPDETL----IMLEET-----RDSIYF 230
                    89***************8.99988877999999******9**************************998877776....333333.....467*** PP

                    TTTCCHHHHHHHHHHHHHHHHHHTTSSSEEEETTSS--TT-BTTB-BTTBSS-HHHHHHHHHHHCC-..SS-EEEEE-SSS--HHHHHHCTT-TTE CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Hist_deacetyl  84 spktlkaallavgavleavdavlsgsvkaafvlvrPpgHHakaseasGFClvNnvaiaikylqakhe..lkrvailDvDvHhGnGteeafysdpdv 177
                    +  t+  all++g+++e++ av++++vk+a++++rPpgHHa++++++GFCl+Nnv ia+k+ q++ +  +++++i+D+DvHhGnG ++afy+dp+v
     EEA20105.1 231 NRLTYASALLSAGGAIETCLAVATRKVKNAIAVIRPPGHHAEHDKTMGFCLFNNVSIAAKVCQRQLGeaCRKILIVDWDVHHGNGIQKAFYDDPNV 326
                    **************************************************************997665688************************* PP

                    EEEEEEE-.CCTSTT..SS--TT---SGGGTTSEEEEEE-T.T-BHHHHHHHHHHCHHHHHCCH--SEEEEEE-STTBTTSTT-S-BB-HHHHHHH CS
                    xxxxxxxx.xxxxxx..xxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Hist_deacetyl 178 ltlSiHry.egifyP..gtgaledlgegkgkgfnlnvplee.gtgdeeylkvfeeilrpvleefkPdlilvsaGfDalkgdplgelnlsvegykel 269
                    l++S+H y +g+fyP  ++g+++ +ge +g g+n+n+p++  g+gd +y+++f+++++p++ ef+Pdl++v  GfDa++gd+lg++ +++  y+++
     EEA20105.1 327 LYMSLHVYaDGKFYPggKEGNWDHVGEVAGLGKNINIPWPSqGMGDGDYMYAFQQVVMPIATEFDPDLVIVASGFDAAAGDELGGCFVTPACYSHM 422
                    ********88*****9889********************8769***************************************************** PP

                    HHHHCCCHGS-G.EEEEE-S---HHHHHHHHHHHHHHH CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Hist_deacetyl 270 tkklaeladkvkkvvllleGGYnlealaravtavlsal 307
                    t++l++la+  +kv ++leGGYn +++++++ av+++l
     EEA20105.1 423 THMLMTLAN--GKVAVCLEGGYNFRSISKSALAVTKTL 458
                    ********9..59*********************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (780 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       438  (0.0244297); expected 358.6 (0.02)
Passed bias filter:                      396  (0.0220871); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.70u 0.32s 00:00:01.02 Elapsed: 00:00:00.50
# Mc/sec: 4700.39
//
Query:       EEA20106.1  [L=1036]
Description: a-pheromone processing metallopeptidase Ste23 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.7e-97  324.1   0.8    1.4e-96  323.1   0.8    1.5  1  Peptidase_M16_M  Middle or third domain of peptidase_M16
    4.5e-35  121.3   0.1    1.6e-21   77.1   0.0    2.7  2  Peptidase_M16_C  Peptidase M16 inactive domain
    2.7e-30  105.3   7.9    1.2e-28  100.0   2.7    4.0  3  Peptidase_M16    Insulinase (Peptidase family M16)


Domain annotation for each model (and alignments):
>> Peptidase_M16_M  Middle or third domain of peptidase_M16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  323.1   0.8  2.3e-100   1.4e-96       1     278 [.     410     698 ..     410     699 .. 0.96

  Alignments for each domain:
  == domain 1  score: 323.1 bits;  conditional E-value: 2.3e-100
  Peptidase_M16_M   1 FrFkekeepsdyvsslaenmqk.yppedvlsgpylleeydpelikellssLtpenarivlvske...t.dekekwygteYsvekiseelleewk 89 
                      FrFk+k+++s+++s+l++ mqk +p+e++lsg++ll+++d++li + ls+L+ +n+r+++vs++   + d kekwygt Y+ eki++++l+e++
       EEA20106.1 410 FRFKQKSPASRFTSRLSSVMQKpLPREWLLSGNNLLRKFDADLITKALSYLRSDNFRLMIVSQHfpgDwDAKEKWYGTDYKEEKIPQDFLTEIR 503
                      9**************************************************************7686477************************ PP

  Peptidase_M16_M  90 sae......eneeLhLPepNpFiptdfslkkesesepakaPelirdtelvrlWykkDdtFkvPkasvrlklrsplasksprnavltelfvellk 177
                      +a       + ++Lh+P++N+Fipt++s++k++ ++pa+ P+lir ++ vr+WykkDd+F+vPka v+++lr+ l+ ++p n v ++l++el++
       EEA20106.1 504 NALasapseRVSDLHMPHKNEFIPTRLSVEKKEVAQPAPTPKLIRLDDHVRVWYKKDDRFWVPKATVHITLRNSLVWATPANHVKAKLYCELVR 597
                      774467888889*****************977566*********************************************************** PP

  Peptidase_M16_M 178 dslneylydAelAglsyslssskeglelsvsGYndklpvLlekvleklknfeikedrFevikekllrelknfklekpyqqarellsslleekaw 271
                      d+l ey+ydAelAgl+y+ls+s  gl++sv GYndk++vLlekv+ +++++ + +drF++ike+l+r+++n+++++py q+ +++++l+ ek+w
       EEA20106.1 598 DALVEYSYDAELAGLDYNLSASIFGLDVSVGGYNDKMSVLLEKVVTTMRDLVVLPDRFKIIKERLTRAYRNAEYQQPYYQVGDMTRYLTAEKTW 691
                      ********************************************************************************************** PP

  Peptidase_M16_M 272 tleelle 278
                       +e++++
       EEA20106.1 692 INEQYAA 698
                      ***9986 PP

>> Peptidase_M16_C  Peptidase M16 inactive domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.1   0.0   2.7e-25   1.6e-21       5     181 ..     226     404 ..     224     405 .. 0.93
   2 !   41.3   0.1   2.6e-14   1.5e-10       2     181 ..     703     882 ..     702     884 .. 0.82

  Alignments for each domain:
  == domain 1  score: 77.1 bits;  conditional E-value: 2.7e-25
                      HHHHHHHHHHSSGGGEEEEEEESS-HHHHHHHHHHHHTTSTHHSH.CSGSCTSSSSSGGGSSEEEEEEEESSSSSEEEEEEEEEECTCTHTTHH CS
  Peptidase_M16_C   5 edlkefykkfYrpenmvlaivGdvdheelvkliekyfgdlkaska.ppakptgepltpatlkkppvvlkkldeeqahlslafegpskendeddl 97 
                       ++ ef+kk+Y++++m+l++ G  + ++l++++ ++f+++++++  +++ + ++pl+  +l ++ + ++ +d  + +l ++f++++ +  ++ l
       EEA20106.1 226 SKFIEFHKKHYSANRMKLVVLGRESLDQLESWVVELFSEVQNKNLpQNRWDDVQPLSADQLCTQVFAKPVMD--SRSLDIYFPFLDEDELYETL 317
                      6899*************************************9998767778888999999999999999999..******************** PP

                      HHHHHHHHHHSSTTSHHHHHHHTTTTSESEEEEEEEEES.SCEEEEEEEEEECT...THHHHHHHHHHHHHHHHHHTS-HHHHHHHHH CS
  Peptidase_M16_C  98 alavlntlLgggmesrLytnlrekeglaysvsafndsyr.dsglfgisatadpe...nveevvevilkelrklkkeglteeelerakn 181
                      +  ++++l+g++  +++ + ++  +g+a + sa+ +s   +s +f+is+ ++ +   ++ e+v+ i+++++++k+  + ++  ++ +n
       EEA20106.1 318 PSRYISHLIGHEGPGSILSYIK-AKGWANGLSAGAMSVGpGSAFFTISVRLTEDgltHYKEIVKIIFQYIAMIKERAPEKWIYDEMQN 404
                      **********************.***********776667**********************************99888877777665 PP

  == domain 2  score: 41.3 bits;  conditional E-value: 2.6e-14
                      H-HHHHHHHHHHHSSGGGEEEEEEESS-HHHHHHHHHHHHTTSTHHSHCSGSCTSSSSSGGGSSEEEEEEEES...SS.SSEEEEEEEEEECTC CS
  Peptidase_M16_C   2 ltredlkefykkfYrpenmvlaivGdvdheelvkliekyfgdlkaskappakptgepltpatlkkppvvlkkl...de.eqahlslafegpske 91 
                      + ++d+ +f+ +  r++++++ ++G++  e+++k+  +    +  s   p+ +++++++   + ++ ++ +++   ++  ++++++++ +  ++
       EEA20106.1 703 IEADDVAAFFPQLLRQNHIEVLAHGNLYKEDALKM-TDIVENIMRSRTLPQSQWHVRRNIIFPPGSNYIYERQlkdPQnVNNCIEYYLFVGKIT 795
                      789***************************99999.5555555555555677777777766666555555555566443577777777777777 PP

                      THTTHHHHHHHHHHHHSSTTSHHHHHHHTTTTSESEEEEEEEEESSCEEEEEEEEEECTTHHH....HHHHHHHHHHHHHHHTS-HHHHHHHHH CS
  Peptidase_M16_C  92 ndeddlalavlntlLgggmesrLytnlrekeglaysvsafndsyrdsglfgisatadpenvee....vvevilkelrklkkeglteeelerakn 181
                      ++   ++l +l+++ ++      +++lr ke+l+y v ++ +  +  + +g  + +++e++++    +++ +l++++k  +e +teee+e +k+
       EEA20106.1 796 DEVLRAKLLLLAQMTEEP----AFDQLRSKEQLGYVVWSGAR--YSATTIGYRVIIQSERTAQylegRIDNFLAQFAKTLDE-MTEEEFESHKR 882
                      888888888888888888....******************88..5579***********88888889***************.********998 PP

>> Peptidase_M16  Insulinase (Peptidase family M16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.0   2.7     2e-32   1.2e-28       3     149 .]      33     199 ..      31     199 .. 0.98
   2 ?   -0.3   0.0      0.16   9.6e+02      70     108 ..     785     823 ..     778     829 .. 0.77
   3 ?    2.8   0.1     0.017     1e+02      60     118 ..     830     891 ..     819     902 .. 0.79

  Alignments for each domain:
  == domain 1  score: 100.0 bits;  conditional E-value: 2e-32
                    EEEE-TSSSEEEEEEEES-SGGGSCTTTTTHHHHHHHHTTSBBSSSCH.HHHHHHHHHTTCEEEEEEESSEEEEEEEEEGGG.............. CS
  Peptidase_M16   3 alesdppaktsavglvvdaGSryepkdlnGlAHllehmafkgTkkyps.nklaeeleklGgslnAttsrentvYyvevlskd.............. 83 
                    +l++dp +++++++  v++G ++++++++G+AH +eh++f+gT+kyp+ n++ ++l+++ gs+nA+t   +t+Y++ev+++               
     EEA20106.1  33 LLVHDPDTDKASASANVNVGNFSDEEAMPGMAHAVEHLLFMGTEKYPKeNAYNQYLASHSGSSNAYTGAIETNYFFEVAATGeskspesangeksa 128
                    789******************************************************************************999************ PP

                    ................HHHHHHHHHHHHHSBTTSHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHTTTSGGGSHSS-TH CS
  Peptidase_M16  84 ................lekaldvladvfkaplleesevererkvvekeveavdaepekvveenlhaaayrekalgrsllgpe 149
                                    l +ald++a++f+apl+ es+++r       e+ avd+e      +nl+++ +r  +l++sl++pe
     EEA20106.1 129 vsssttalskdsatspLYGALDRFAQFFIAPLFLESTLDR-------ELRAVDSEN----KKNLQSDVWRLMQLNKSLSNPE 199
                    ****************************************.......*********....*******************995 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.16
                    SSEEEEEEEEEGGGHHHHHHHHHHHHHSBTTSHHHHHHH CS
  Peptidase_M16  70 rentvYyvevlskdlekaldvladvfkaplleesevere 108
                     e+  +  +++++ l   l +la+++ +p++++   +++
     EEA20106.1 785 IEYYLFVGKITDEVLRAKLLLLAQMTEEPAFDQLRSKEQ 823
                    566667777777788888999**********99887775 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.017
                    TTCEEEEEEESSEEEEEEEEEGGGHHHHHH.HHHHHHHSB.TTSHHHHHHHHH.HHHHHHHH CS
  Peptidase_M16  60 lGgslnAttsrentvYyvevlskdlekald.vladvfkap.lleesevererk.vvekevea 118
                     G++++Att   + + + e ++++le+ +d +la++ k   +++e+e+e  +  +++k++e+
     EEA20106.1 830 SGARYSATTIGYRVIIQSERTAQYLEGRIDnFLAQFAKTLdEMTEEEFESHKRsIINKRLEK 891
                    699999********************9998345555555489*******9888455555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1036 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       776  (0.0432818); expected 358.6 (0.02)
Passed bias filter:                      601  (0.0335211); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.79u 0.30s 00:00:01.09 Elapsed: 00:00:00.47
# Mc/sec: 6658.67
//
Query:       EEA20107.1  [L=282]
Description: cleavage and polyadenylation specific factor 5 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-81  271.0   0.0    5.1e-81  270.8   0.0    1.1  1  NUDIX_2   Nucleotide hydrolase


Domain annotation for each model (and alignments):
>> NUDIX_2  Nucleotide hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  270.8   0.0   2.9e-85   5.1e-81       1     188 []      27     220 ..      27     220 .. 0.96

  Alignments for each domain:
  == domain 1  score: 270.8 bits;  conditional E-value: 2.9e-85
     NUDIX_2   1 keiklYplsnyefekkeklkekdksveeklkrlkesyekeglrrtveavllvhrhelphvLlLqielqefkLpggklksgedeiegLkrkLakklskek 99 
                 ++i+lYplsny+f++ke++ e+d sv ++lkrl+e+y+  g+rrt+e+vl++h+h++phvL+Lqi++++fkLpg++l++++dei g+k++L+++l++  
  EEA20107.1  27 QTIRLYPLSNYTFGTKENQPEEDPSVLARLKRLEEHYDLYGMRRTCEGVLVCHEHNHPHVLMLQIANAFFKLPGDYLHHDDDEIAGFKTRLNERLAPVG 125
                 589*********************************************************************************************664 PP

     NUDIX_2 100 ev......eeeievgellgewwrpnfesslypYlPahitrpkEliklylvtLpekckfavpknlkLlavpLfelyenaakygiaisslpqllsrf 188
                 ++      +e++evg++l++wwrpnfe+++yp+lP h+trpkE++klyl++Lp+k++++vpkn+kLlavpLfely+n+a+yg+++s++p+llsr+
  EEA20107.1 126 SQfsgegvNEDWEVGDTLAQWWRPNFETFMYPFLPGHVTRPKECKKLYLIQLPKKKVLSVPKNMKLLAVPLFELYDNTARYGPQLSAIPHLLSRY 220
                 33344444**************************************************************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (282 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       280  (0.0156172); expected 358.6 (0.02)
Passed bias filter:                      265  (0.0147805); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.46
# Mc/sec: 1854.77
//
Query:       EEA20108.1  [L=306]
Description: lipase precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    4.1e-27   94.8   0.1    5.9e-27   94.3   0.1    1.2  1  Lipase_3   Lipase (class 3)
    4.8e-07   29.7   0.2    1.1e-06   28.6   0.2    1.6  1  Lipase3_N  Lipase 3 N-terminal region
  ------ inclusion threshold ------
       0.16   11.1   0.1       0.21   10.6   0.1    1.1  1  DUF2048    Abhydrolase domain containing 18


Domain annotation for each model (and alignments):
>> Lipase_3  Lipase (class 3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.3   0.1   9.8e-31   5.9e-27       1     140 [.     104     245 ..     104     247 .. 0.96

  Alignments for each domain:
  == domain 1  score: 94.3 bits;  conditional E-value: 9.8e-31
                 EEEE----------------EEE-HHHH-GTT-EEEHHHHHHHHS-HHHHHHHHHHHHHHHTT-EEEEEEEETHHHHHHHHHHHHHHHTT-SS..---E CS
    Lipase_3   1 vvafRGtesakdwltdldfslteakellekeggkvhsgfleayeeslreqvlkelkrllekypeysivvtGHSLGgalAlLaaldlvengene..kkkv 97 
                 v+afRG  s+++ +t+ld++l+  + +    g+ vh+gf +++   +   +++el +   +   ++++vtGH  GgalA+Laa+ ++++      + +v
  EEA20108.1 104 VLAFRGARSIENGVTKLDTRLVGTSLCGATVGCLVHEGFQDSWD-PVSARITTELTNAQVATGFTTLIVTGHGVGGALATLAATRFRTTPIPGipAANV 201
                 79************************9999**************.************9999999*************************987799**** PP

                 EEEEES----B-HHHHHHHHT-TTE.EEEEEEETT--GGG-S-S CS
    Lipase_3  98 tvvtfGqPrvgnkefaklvdsqlnk.kvlrvvntnDivPrlppl 140
                 +++t+G+Prvgn+ fa++v+ q+   + +rv++t+D++P++p  
  EEA20108.1 202 QLFTYGSPRVGNTVFATFVTTQGAAaNNFRVTHTDDPIPKVPSR 245
                 ********************9999999***************75 PP

>> Lipase3_N  Lipase 3 N-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.6   0.2   1.8e-10   1.1e-06       3      75 ..       8      79 ..       4      80 .. 0.81

  Alignments for each domain:
  == domain 1  score: 28.6 bits;  conditional E-value: 1.8e-10
   Lipase3_N  3 sallalaaatwaektstesrevshtdsedfnfWeqyaaaayfypvprgakiikavycgklrcPevepaeatll 75
                +a++al a++ a +   e+  vs t +  +   eqy+aaay + ++ +a +++++ c  ++cP ve+++at++
  EEA20108.1  8 TAVAALTATATAGLLRREADVVSSTVLARLSLIEQYSAAAY-CTKNDIAAPGTPIACAPGNCPTVEQDLATVS 79
                555555555555555555667888888888999*******6.***************************9985 PP

>> DUF2048  Abhydrolase domain containing 18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.1   3.6e-05      0.21     165     205 ..     156     197 ..     151     231 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 3.6e-05
     DUF2048 165 vllhwlereGyGplgltGlSmGGhmaslaasnwp.kplvlvp 205
                 +l ++    G+  l +tG  +GG  a+laa+ +  +p++ +p
  EEA20108.1 156 ELTNAQVATGFTTLIVTGHGVGGALATLAATRFRtTPIPGIP 197
                 677888889**********************97525777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (306 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       339  (0.0189079); expected 358.6 (0.02)
Passed bias filter:                      267  (0.0148921); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.47
# Mc/sec: 1945.93
//
Query:       EEA20109.1  [L=369]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.1e-87  290.5   0.2    9.8e-87  290.2   0.2    1.1  1  DUF3431   Protein of unknown function (DUF3431)


Domain annotation for each model (and alignments):
>> DUF3431  Protein of unknown function (DUF3431)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  290.2   0.2   5.5e-91   9.8e-87       1     215 []     102     318 ..     102     318 .. 0.96

  Alignments for each domain:
  == domain 1  score: 290.2 bits;  conditional E-value: 5.5e-91
     DUF3431   1 lVvaklkeedtsWveeelpdlqtaiYvvddpsaeltvpankGreamaYltyiidnYdsLpdvvvFvhahraawhndaldydnaallrrlrleavqeeGY 99 
                 lVva++  ++t+W+ ++lpd++++iY+vdd+ a+ltv  nkGre+m+YltyiidnYd+Lpd+++F+h+hr++whnd++ yd + +++r++l++++  GY
  EEA20109.1 102 LVVASMVGDNTTWLYDSLPDWHKSIYIVDDKYADLTVTINKGRESMVYLTYIIDNYDHLPDYMLFIHSHRYQWHNDDPYYDGVPMIKRFQLPYLELIGY 200
                 8************************************************************************************************** PP

     DUF3431 100 vnlrckwepgCpaelkplekee..eekkeeealaeafaelfeeeevpevvaapcCaqFavsrerirkrpreeYvrlrqwlletelddelsGrvleylWh 196
                 vnlrc w  gCp+e++p++++   ++ ++  ++ + f+elf++ +vpe+va++cCaqF v+r +ir+rp+++Y+r++qwll+t+ldd++sGr++ey+Wh
  EEA20109.1 201 VNLRCAWVLGCPDEIHPMTDTLsdDTVHAGPYYFNGFKELFPGAKVPETVAVSCCAQFGVARWKIRERPKSDYERYKQWLLKTDLDDATSGRIMEYSWH 299
                 ******************844333445555599****************************************************************** PP

     DUF3431 197 ilFgkeavaCpdeeecycd 215
                 ++Fg+++++Cp+++ecyc+
  EEA20109.1 300 MIFGMDPIHCPNAAECYCN 318
                 ******************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (369 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       447  (0.0249317); expected 358.6 (0.02)
Passed bias filter:                      355  (0.0198003); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2566.25
//
Query:       EEA20110.1  [L=318]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.2e-77  258.8   0.1    5.5e-77  258.4   0.1    1.1  1  DUF3431   Protein of unknown function (DUF3431)


Domain annotation for each model (and alignments):
>> DUF3431  Protein of unknown function (DUF3431)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  258.4   0.1     3e-81   5.5e-77       1     197 [.     102     300 ..     102     306 .. 0.96

  Alignments for each domain:
  == domain 1  score: 258.4 bits;  conditional E-value: 3e-81
     DUF3431   1 lVvaklkeedtsWveeelpdlqtaiYvvddpsaeltvpankGreamaYltyiidnYdsLpdvvvFvhahraawhndaldydnaallrrlrleavqeeGY 99 
                 lVva++  ++t+W+ ++lpd++++iY+vdd+ a+ltv  nkGre+m+YltyiidnYd+Lpd+++F+h+hr++whnd++ yd + +++r++l++++  GY
  EEA20110.1 102 LVVASMVGDNTTWLYDSLPDWHKSIYIVDDKYADLTVTINKGRESMVYLTYIIDNYDHLPDYMLFIHSHRYQWHNDDPYYDGVPMIKRFQLPYLELIGY 200
                 8************************************************************************************************** PP

     DUF3431 100 vnlrckwepgCpaelkplekee..eekkeeealaeafaelfeeeevpevvaapcCaqFavsrerirkrpreeYvrlrqwlletelddelsGrvleylWh 196
                 vnlrc w  gCp+e++p++++   ++ ++  ++ + f+elf++ +vpe+va++cCaqF v+r +ir+rp+++Y+r++qwll+t+ldd++sGr++ey+Wh
  EEA20110.1 201 VNLRCAWVLGCPDEIHPMTDTLsdDTVHAGPYYFNGFKELFPGAKVPETVAVSCCAQFGVARWKIRERPKSDYERYKQWLLKTDLDDATSGRIMEYSWH 299
                 ******************844333445555599*****************************************************************9 PP

     DUF3431 197 i 197
                  
  EEA20110.1 300 S 300
                 5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (318 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       493  (0.0274974); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2201.55
//
Query:       EEA20111.1  [L=275]
Description: dephospho-CoA kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-43  148.6   0.0    1.9e-43  148.2   0.0    1.1  1  CoaE      Dephospho-CoA kinase
  ------ inclusion threshold ------
      0.014   15.5   0.0       0.11   12.6   0.0    2.2  1  AAA_33    AAA domain
      0.036   14.6   0.2       0.23   12.0   0.0    2.1  2  AAA_18    AAA domain
      0.054   13.2   0.0      0.096   12.4   0.0    1.4  1  HCV_env   Hepatitis C virus envelope glycoprotein E1


Domain annotation for each model (and alignments):
>> CoaE  Dephospho-CoA kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  148.2   0.0   4.3e-47   1.9e-43       1     167 [.       2     187 ..       2     197 .. 0.89

  Alignments for each domain:
  == domain 1  score: 148.2 bits;  conditional E-value: 4.3e-47
                 EEEEEEESTTSSHHHHHHHHHH..TT-EEEEHHHHHHHTTCCTHHHHHHHHHHHG...GGCB....TTSS..E-HHHHHHHHHTSHHHHH....HHHHH CS
        CoaE   1 livgltGgiasGKstvanlfad..lgvpivDaDlvArqvvepgsealkkiveeFg...eeil...dedGe..LdReaLrkkvFadpeekk....aLnal 85 
                 li+gltG ia+GKstv++l+++  +++pi+DaD++Ar+vvepg++ +k+iv++Fg   +++l   d+dG+  L+R aL+k+vF d ee+k    +Ln++
  EEA20111.1   2 LIIGLTGSIATGKSTVSSLLSSppHNLPIIDADVLARKVVEPGTAGYKAIVNYFGpstPDLLlpaDADGKqgLNRPALGKRVFGDSEERKrdrtILNKI 100
                 69*******************999*******************************77755652333457566***********999976533338**** PP

                 HHHHHHHHHHHHHHH--S...SEEEEE-TTTTTTTGGGGSSEEEEEE--.HHHHHHHHHHCC.TSTHHHHHHHHHHS--HHHHHHH- CS
        CoaE  86 lhPlirreikkelakles...kyvlldvPLLvEkqlekliervlvvdve.lelqveRlvard.gvseeevkaiiaaQlseeerlala 167
                 +hP++r+e+ k+l +++      v+ldvPLL+E++++ ++ +v+vv+v+ +  q++Rl ard  +++e++++++++Q + + +++ a
  EEA20111.1 101 VHPAVRWEVYKSLLYYYLrgnWAVVLDVPLLFESGMDVICGTVVVVAVKePAVQMSRLRARDpHLTAEDAENRVKSQGDVQGKVKKA 187
                 **************9998787799***********************972578*********99***************99999987 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   2.5e-05      0.11       4      93 ..       6     144 ..       3     193 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 2.5e-05
      AAA_33   4 lvGlpGsGKstlaerllkklg.avllssdt...........................................lrrrlfgtdqqsktdytrvldr.... 54 
                 l G  ++GKst++  l  + +   +++ d+                                           l +r+fg+ +++k+d+t +++     
  EEA20111.1   6 LTGSIATGKSTVSSLLSSPPHnLPIIDADVlarkvvepgtagykaivnyfgpstpdlllpadadgkqglnrpaLGKRVFGDSEERKRDRTILNKIvhpa 104
                 579999********9987777899999999888889999999999999999999999999999999999999888899996666665444433222223 PP

      AAA_33  55 .lyqilnelarkalsagrnvildatnlsrrerarflklar 93 
                   ++  + l+  +l+ +++v+ld ++l+++ ++ ++  + 
  EEA20111.1 105 vRWEVYKSLLYYYLRGNWAVVLDVPLLFESGMDVICGTVV 144
                 3555777888899999999999999999999865554443 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   5.1e-05      0.23       1      20 [.       4      23 ..       4      44 .. 0.88
   2 ?    0.3   0.0      0.22   9.9e+02      84     120 ..     130     166 ..      86     199 .. 0.65

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 5.1e-05
      AAA_18  1 IlltGtpGvGKttlakeLsk 20
                I+ltG +++GK+t++  Ls+
  EEA20111.1  4 IGLTGSIATGKSTVSSLLSS 23
                89****************86 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.22
      AAA_18  84 aeleseaakdikk.vvLtasp.eelleRlekRgyeeaki 120
                   +es ++++ ++ vv+ +++  + + Rl++R+  ++ +
  EEA20111.1 130 LLFESGMDVICGTvVVVAVKEpAVQMSRLRARD--PHLT 166
                 444444444444455555554466667777776..3333 PP

>> HCV_env  Hepatitis C virus envelope glycoprotein E1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   2.1e-05     0.096     158     186 ..     104     132 ..      90     137 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2.1e-05
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
     HCV_env 158 gahwgvlaglayfsmvgawakvlvvlllv 186
                    w v   l y+ + g+wa vl v ll+
  EEA20111.1 104 AVRWEVYKSLLYYYLRGNWAVVLDVPLLF 132
                 358********************997776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       452  (0.0252106); expected 358.6 (0.02)
Passed bias filter:                      386  (0.0215294); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 1985.06
//
Query:       EEA20112.1  [L=1085]
Description: lysine-specific histone demethylase Aof2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.6e-84  282.6   0.2    1.2e-72  245.7   0.0    2.3  2  Amino_oxidase  Flavin containing amine oxidoreductase
      1e-12   48.2   0.1    2.3e-12   47.1   0.1    1.6  1  SWIRM          SWIRM domain
    1.7e-08   34.5   0.0    3.9e-08   33.4   0.0    1.6  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
      0.001   19.5   2.1     0.0028   18.0   2.1    1.7  1  HMG_box        HMG (high mobility group) box
      0.002   17.8   1.1      0.002   17.8   1.1    1.9  2  DAO            FAD dependent oxidoreductase
     0.0063   16.5   0.1       0.04   13.9   0.0    2.2  2  NAD_binding_9  FAD-NAD(P)-binding
  ------ inclusion threshold ------
       0.02   14.1   0.4      0.075   12.3   0.0    1.9  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
      0.051   12.8   0.0      0.096   11.9   0.0    1.3  1  Thi4           Thi4 family
      0.065   12.5   0.4        1.5    8.0   0.0    2.2  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase


Domain annotation for each model (and alignments):
>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.7   0.0   5.9e-12   1.2e-08       1      64 [.     300     386 ..     300     446 .. 0.75
   2 !  245.7   0.0   5.8e-76   1.2e-72     158     452 .]     565     867 ..     542     867 .. 0.91

  Alignments for each domain:
  == domain 1  score: 34.7 bits;  conditional E-value: 5.9e-12
                    HHHHHHHHHH.........HHTTEEEEEEESSSSSBTTS-EEEET.........T..EEEESS--EEET..TTHHHHHHHHH.TTCC CS
  Amino_oxidase   1 laGLaaArqL.........lsaGfdVtvlEardrvGGRirtvrsd.........G..ylielGamwftg..agnpllellke.lgle 64 
                    +aGLa+ArqL         +   ++++vlE+r r+GGRi++++++         G   ++e+Ga+++ g   gnpl ++++  l l 
     EEA20112.1 300 VAGLACARQLeglyqqyrdKVTSLKIIVLEGRRRIGGRIYSHPLKshqkttlpkGlrPTAEMGAQIIVGfdRGNPLDAIIRSqLALR 386
                    69**********98876544444**********************8888777774669************99999988888734443 PP

  == domain 2  score: 245.7 bits;  conditional E-value: 5.8e-76
                    HHHHHHHHHHHHHHHHHCHTSTTTTCBHHHHTCCCCHHHHHTSCCCEETTHTHHHHHHHHHTTTTEEEETSEEEEEEEE......ETTCEEEEETT CS
  Amino_oxidase 158 drliepelfaklefasglfagdpselsaklalpllwelegfggslllprgGlsqlpealaeelrgldirlntrVkeikr......egdgvtvtled 247
                    d+ ++ +++a+le+a+++      +  ++l+ ++++  ++f+g++  + gG++qlp+ l++   +ld+r+n+ V +i++       + + tv++e+
     EEA20112.1 565 DMRLLNWHYANLEYANAT-----NLNALSLSGWDQDMGNEFEGEHSQVIGGYQQLPRGLWAFPTKLDVRTNETVVNITYdavgksKNRKTTVHTEN 655
                    555667************.....778899999***********************************************77755333348888888 PP

                    STEEEESEEEE-S-HHHHH..SSEEESCCSHHHHHHHHHSEEEEEEEEEEEESSGGSGCSTSE.CE..........CECCCEEETTTEEEEECCEC CS
  Amino_oxidase 248 gevveaDaVvvTvplgvlk..ailfsPplpdekaeairnlgfgsvnkvilefdrkfwednalg.qg..........vlvseltttlgeafissdfp 330
                    g   +aD+Vv T +lg+lk  +++f+P lpd+k  a+++lgfg++nkv+l fd++fw+ n  + +g           + ++ ++ +g+ +++  ++
     EEA20112.1 656 GPI-SADHVVYTGSLGTLKhrTVEFTPALPDWKIGAVDRLGFGVLNKVVLVFDQPFWDTNR-DmFGllreaevpgsMSQAHYSKNRGRFYLF--WN 747
                    885.*******************************************************98.445544456777577777777777777777..** PP

                    CCSTTTEEEEEEEEECHHHHHHHTTS-HHHHHHHHHHHHHHHHT.GTSSTCSEEEEEECCTETTTSSSEEE.BTTHHHHHHHHHHCHHCSTTEEE. CS
  Amino_oxidase 331 srappgkglvllvyvggdaaneleslsdeelvqavlrdLrklfg.eevpepkatlvtrWhtdplargsysyvsvgpghedydplakpegdprlffA 425
                      +++g ++ l+++++gdaa++ e+l+dee+v +vl++Lr++f+ + vp+p +t+vtrW++d+++rg+ysyv++ + + dyd  a+   +++l+fA
     EEA20112.1 748 CIKTSGIPV-LIALMAGDAAHQAEKLPDEEIVTEVLSELRNIFKsKTVPDPLETIVTRWKSDKFTRGTYSYVAADALPGDYDLIAQA--VGNLHFA 840
                    *******99.*****************************************************************************..******* PP

                    SGGGCTTTTTSHHHHHHHHHHHHHHHH CS
  Amino_oxidase 426 GehtsreypgtvegAilSGlraAaril 452
                    Ge+t+ ++p+tv+gA+lSGlraAa+i+
     EEA20112.1 841 GEATCATHPATVHGAYLSGLRAAAEIM 867
                    ************************995 PP

>> SWIRM  SWIRM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.1   0.1   1.1e-15   2.3e-12       5      89 .]     191     269 ..     186     269 .. 0.93

  Alignments for each domain:
  == domain 1  score: 47.1 bits;  conditional E-value: 1.1e-15
       SWIRM   5 wFdpdslhpiEkellselfngkdktpeeYlkiRnkiialyrenpkeyltvteaqkalkrrrltgidvnllsrihefLerwGlINf 89 
                  ++p +lh+ E+++l++++ +   + ++Yl+iRn i++l+++np   +t++ea  ++k    + +++ l+  ++e+L r+G+INf
  EEA20112.1 191 RLNPFALHKNEQNALQHHLCH--LHVTTYLNIRNGILRLWTRNPMISVTREEALGCAK----DFRWMGLADFAYEWLIRNGYINF 269
                 567889*************87..9*********************************9....5579******************9 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.4   0.0     2e-11   3.9e-08       1      62 [.     295     376 ..     295     381 .. 0.78

  Alignments for each domain:
  == domain 1  score: 33.4 bits;  conditional E-value: 2e-11
                    EE--SHHHHHHHHHHH......CC...TEEEEEE-SSSSSSGGG-EECE.........TT..CEECTS---EEETTHHHHCH CS
  NAD_binding_8   1 IvGaGlsGlvaAylLa......ka...gfdvlllekrdrlGGraasyev.........pg..vrvdygahifhgsgyypnvr 62 
                    IvGaG++Gl++A+ L       ++    +++ +le r+r+GGr++s  +         +g   +++ ga+i+ g+++ + + 
     EEA20112.1 295 IVGAGVAGLACARQLEglyqqyRDkvtSLKIIVLEGRRRIGGRIYSHPLkshqkttlpKGlrPTAEMGAQIIVGFDRGNPLD 376
                    9**************966654423345669*****************88666555553338899999999999988766665 PP

>> HMG_box  HMG (high mobility group) box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   2.1   1.4e-06    0.0028      20      59 ..    1007    1048 ..     999    1057 .. 0.80

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 1.4e-06
                  HHHSTTS-..HHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHH CS
     HMG_box   20 kaenPelk..naeiskklgekWkalseeeKkkYeekaekeka 59  
                  ++ nPe+k    ei   lg++W++  ee K++Y+e+    + 
  EEA20112.1 1007 ATNNPEAKaaRDEIRAVLGQMWREADEETKRPYQEQMVVNRR 1048
                  568999996667**********************98776665 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   1.1     1e-06     0.002       2      35 ..     293     336 ..     292     340 .. 0.81
   2 ?   -3.6   0.2       3.2   6.3e+03     162     201 ..     626     668 ..     625     677 .. 0.64

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 1e-06
                 EEEECTSHHHHHHHHHH.....HHTT.......EEEEESSSSTTSS CS
         DAO   2 vviiGGGiiGlstAyeL.....arrg.......Vtllekgdiagsg 35 
                 +vi+G+G++Gl++A++L     +          +++le ++++g g
  EEA20112.1 293 IVIVGAGVAGLACARQLeglyqQY-RdkvtslkIIVLEGRRRIG-G 336
                 8****************6665322.13678899*****999988.4 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 3.2
                 EEEESECEEEEEEEE......TCEEEEEEECT.EEEEEEEEEEE--G CS
         DAO 162 eilegtevtgleeed......gkvwgverttp.gendaadavVnaaG 201
                 +++++++v+++  +d      ++ ++v  +t+ g + +ad+vV +  
  EEA20112.1 626 DVRTNETVVNI-TYDavgkskNRKTTV--HTEnGPI-SADHVVYTGS 668
                 57888888888.333354555566777..4444765.5599998765 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   0.0     2e-05      0.04       1      44 [.     294     341 ..     294     350 .. 0.82
   2 ?   -0.7   0.0      0.63   1.2e+03     121     151 ..     630     665 ..     566     668 .. 0.74

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 2e-05
  NAD_binding_9   1 aivGaGprGlavlerLlara....kkkspleitlfdp.sepgagrvwrt 44 
                    +ivGaG++Gla++++L        +k ++l+i + +  + +g gr+++ 
     EEA20112.1 294 VIVGAGVAGLACARQLEGLYqqyrDKVTSLKIIVLEGrRRIG-GRIYSH 341
                    7***********99985554446888899********55668.***986 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.63
  NAD_binding_9 121 raevvdleera.....dgqavlladgaslaadaVvL 151
                    +++vv+++ +a     ++ + + +++  + ad+Vv 
     EEA20112.1 630 NETVVNITYDAvgkskNRKTTVHTENGPISADHVVY 665
                    445555544332221144566778888999999986 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   3.8e-05     0.075       3      22 ..     293     316 ..     291     356 .. 0.76
   2 ?   -1.2   0.1      0.46   9.1e+02     198     233 ..     625     665 ..     620     668 .. 0.61

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 3.8e-05
                  EEEE--SHHHHHHHHHHHH....H CS
                  xxxxxxxxxxxxxxxxxxx....x RF
  Pyr_redox_2   3 vvviGgGpAGlaaaltlaq....a 22 
                  +v++G+G+AGla+a++l      +
   EEA20112.1 293 IVIVGAGVAGLACARQLEGlyqqY 316
                  7999*********99998655443 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.46
                  EEEEESCEEEEEEETTE.....EEEEEETTSCEEEESEEEE CS
                  xxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 198 vevklgtsvkeidgnge.....klevvledgeeidadlvvv 233
                   +v+++++v++i+ +       + ++v++++  i ad vv+
   EEA20112.1 625 LDVRTNETVVNITYDAVgksknRKTTVHTENGPISADHVVY 665
                  46777777777777766654332225555555577777775 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   4.8e-05     0.096      20      56 ..     293     337 ..     288     341 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 4.8e-05
                 EEEE--SHHHHHHHHHHH.......HC.TTS-EEEEESSSS--TT CS
        Thi4  20 vvivGaGssGLtaayyla.......kk.pdlkvailersvspGGG 56 
                 +vivGaG +GL++a+ l         k   lk+++le +  +GG 
  EEA20112.1 293 IVIVGAGVAGLACARQLEglyqqyrDKvTSLKIIVLEGRRRIGGR 337
                 89*************985333333223478999999999999986 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   0.0   0.00075       1.5       1      18 [.     294     311 ..     294     350 .. 0.65
   2 ?    2.1   0.1     0.046        92      95     130 ..     624     665 ..     619     677 .. 0.78

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00075
  Pyr_redox_3   1 iIiGaGPaGlaaaielkk 18 
                  +I+GaG aGla+a +l+ 
   EEA20112.1 294 VIVGAGVAGLACARQLEG 311
                  7************99864 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.046
  Pyr_redox_3  95 elpiklfeeVesvk.....k.edegfevetsketyeAkkvii 130
                  +l+++++e+V +++     k ++++ +v+t+++ ++A++v+ 
   EEA20112.1 624 KLDVRTNETVVNITydavgKsKNRKTTVHTENGPISADHVVY 665
                  799999999988862222233567799************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1085 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       660  (0.0368119); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.81u 0.31s 00:00:01.12 Elapsed: 00:00:00.49
# Mc/sec: 6642.53
//
Query:       EEA20113.1  [L=527]
Description: O-methylsterigmatocystin oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-65  222.1   0.0    1.6e-65  221.7   0.0    1.1  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  221.7   0.0   8.7e-70   1.6e-65       1     439 [.      31     461 ..      31     474 .. 0.88

  Alignments for each domain:
  == domain 1  score: 221.7 bits;  conditional E-value: 8.7e-70
                 --SESEHHCCHCHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGH.HHHHHH CS
        p450   1 Ppgptplplvgnllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfang.ekwkkl 98 
                 P gp+ lp++gnl+ql r +  h ++++++k+yg ++++k g+++++++++   v+e+   kg   s+rp +  ++ +    ++ ++l+ ++ ++w+ +
  EEA20113.1  31 PNGPPTLPIIGNLHQLPR-RRAHLKYTEMAKEYGGLYTVKAGHHTIAIITDRRVVRELIEEKGPTASNRPSSYIIQRL--IGENDHLLTLQYgQTWRLI 126
                 899**************6.889999**************************************999999887777764..4555555555555****** PP

                 HHHHHHHHTSHSTT.THHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCCCH CS
        p450  99 Rrfltptltsfgkl.sleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelssllskssvqllllfp 196
                 R+++++++ ++  +   e +  + ae  v++lr+    +   +  ++  ++ +++++s+++g+r+ ++++     l ++ ++   ll+   + +++++p
  EEA20113.1 127 RKLVHQHFKDS--McDNEHVYLQHAE-GVQMLRDFIVDP--ENNMQHPRRYSCSIMTSTVYGVRIPSIKSAYMGHLYEMLDTFTALLELGATPPVDFYP 220
                 *********99..4344444444443.345555555555..3458999***********************99999999999999999999******** PP

                 HHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHH CS
        p450 197 llkylptkllrklkeavkklkdlldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPev 295
                 +lk    + lr+++ +   +        ++rr+  + ++ ++ +++d +l ++   ++   +s + l    + l  +G++T +  +  ++  + k Pe+
  EEA20113.1 221 FLKNNGIPPLRHVQTC-ACP------TRQNRRKGEEGEHPNTSSLMDKVLGER---DNL-GFSTHKLSFIGGGLVEGGSETPACMILTFIGAMTKWPEI 308
                 9999999999999966.433......334444444444456778999999997...555.8************************************** PP

                 HHHHHHHHHHHCCTTTT-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEETTEEE-TT-EEEEEHHHHHT-TTTSSSTTS--GGGGB-TTS. CS
        p450 296 qeklreEidevlgdkreptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirgylipkGtevivnlyalhrdpevfpnPeeFdpeRFldekg. 393
                 q+k + Eid v+g++r+pt++d + lpy+ a+ kE  R +pv+pl++p+ +  d  i+g+l+pkG + i+n+++l++d++++ nPe+FdpeRF ++k+ 
  EEA20113.1 309 QKKAQVEIDAVIGEDRSPTWADYACLPYVAAITKECVRWRPVAPLGMPHSLDADEWIDGRLLPKGATLILNIWGLNHDENHYRNPEVFDPERFYNNKEk 407
                 *************************************************************************************************9* PP

                 .........CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEEST CS
        p450 394 .........nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqp 439
                          +++ +s  +   GaG+R C G +lA+  +++++a lL  F++e  p
  EEA20113.1 408 vplaheymnKQDYNSRDHYSYGAGRRFCTGIHLAERDMFIAMAMLLWAFNFEK-P 461
                 ********977799*************************************95.3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (527 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       444  (0.0247643); expected 358.6 (0.02)
Passed bias filter:                      425  (0.0237046); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.33s 00:00:00.90 Elapsed: 00:00:00.49
# Mc/sec: 3246.36
//
Query:       EEA20114.1  [L=601]
Description: alpha-1,6-mannosyltransferase subunit (Ecm39), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-44  153.1  17.8    1.6e-44  152.8  17.8    1.1  1  Glyco_transf_22  Alg9-like mannosyltransferase family
  ------ inclusion threshold ------
        1.2    8.8   4.3       0.37   10.4   0.2    2.2  2  CPP1-like        Protein CHAPERONE-LIKE PROTEIN OF POR1-like


Domain annotation for each model (and alignments):
>> Glyco_transf_22  Alg9-like mannosyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  152.8  17.8   1.8e-48   1.6e-44      45     399 ..      65     437 ..      52     457 .. 0.84

  Alignments for each domain:
  == domain 1  score: 152.8 bits;  conditional E-value: 1.8e-48
  Glyco_transf_22  45 WEyspkygiRSylfllllalpyrllaelvadskiavlyapRlllallsalidyylfravcrkygseiakialllslsswglfvfstrtfsnsle 138
                      +++ +  g  + +f+ +lal   +  +++  +++   +++R++l+l++al+ ++ +r +++++g+ +a++ l+++ s+++++++ +rt+sn ++
       EEA20114.1  65 YDHFSFPGAVPRTFIGALALASASSPVVWFYENVDRQILVRAILGLFNALSLIVYARGIQKSLGNVTAYWYLIFQASQFHVAYYASRTLSNMFS 158
                      555566666677777777666666666666666666899******************************************************* PP

  Glyco_transf_22 139 mlltsialyllsellsrenksss........................nekylvavlliavlavliRptsallwlplvlflllrlvkkrsktflf 208
                        +t++al ll+  +  +++ +s                        + +y++a+++++v+++++R + all++   ++++l  + + ++ +  
       EEA20114.1 159 FCVTTLALRLLLP-GPDMIDAKSikstktsktqqtakatkttaaplpYARYRLALIFFTVAGIIFRSELALLLATNTIYYFLTQRIRIWQDI-- 249
                      ***********95.77777777788899*******************99********************************66666666665.. PP

  Glyco_transf_22 209 liialvllvlllvlvlviliDslfYgkf.vftplnflkyNvlsnlsslyGvhPwyfYllqnlpnilgvlllavllgllvllsrkvsr.llllll 300
                        +  +++ l++ l+++++iDs+f++ f ++++++ +k+Nv+s + s +Gv Pw+fY++++lp++l+  l  +++ ++ l++    r  l+l++
       EEA20114.1 250 --VPAGIIGLFVGLTATVAIDSYFWQDFpLWPEFSAFKFNVVSGQASAWGVDPWFFYFTSALPRLLLNPLTWLVCIPASLIAGTTRRvSLSLVV 341
                      ..8888888888899**********776489**********************************999888888999999655555555699** PP

  Glyco_transf_22 301 tilltLlvysllpHKElRFllpvlPlillsaavlltrlsresakvskklsllvllllfnvvlalllglvhqagvillv..evmseleetkrknr 392
                      + l ++++ys++pHKE RF+++++P ++  aa + +++    +++++k s+++ ll f++vl++l++++    ++l +  +  +  ++ +r++ 
       EEA20114.1 342 PSLAFVAIYSFQPHKEWRFIIYIIPALTAAAAQGAANI----WTRRGK-SIVYRLLSFSLVLSTLASFLFSTFILLPIssANYPGAQAIQRAHF 430
                      **************************999999988888....999999.899999999999999888877666665555655555666666666 PP

  Glyco_transf_22 393 kekkets 399
                      + ++ + 
       EEA20114.1 431 HGQGTQP 437
                      5555544 PP

>> CPP1-like  Protein CHAPERONE-LIKE PROTEIN OF POR1-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.2   4.1e-05      0.37      84     174 ..     189     279 ..     173     296 .. 0.71
   2 ?   -1.7   0.6      0.21   1.9e+03     117     133 ..     377     406 ..     312     410 .. 0.62

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 4.1e-05
   CPP1-like  84 lqesldtPssedlliraavflvlavltlvapaesvpalllalglgasiyflnrKekklgravlltlvgLvvGlllGsllasllqvdvalsg 174
                 +q++ ++ +++   ++ a + + +++  va+     +l+l l++ +  yfl+++ +     v  +++gL+vGl++  ++ s++ +d++l +
  EEA20114.1 189 TQQTAKATKTTAAPLPYARYRLALIFFTVAGIIFRSELALLLATNTIYYFLTQRIRIWQDIVPAGIIGLFVGLTATVAIDSYFWQDFPLWP 279
                 444444444444444444444444444444444478999999**************************************99988865544 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.21
   CPP1-like 117 s.............vpalllalglgasiyf 133
                 +              +++ l+l+++as++f
  EEA20114.1 377 AniwtrrgksivyrLLSFSLVLSTLASFLF 406
                 223333333445555666666666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (601 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       595  (0.0331865); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.31s 00:00:00.95 Elapsed: 00:00:00.49
# Mc/sec: 3709.55
//
Query:       EEA20115.1  [L=85]
Description: protein transport protein yos1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.5e-36  122.1   0.4    9.4e-36  121.9   0.4    1.0  1  Yos1      Yos1-like


Domain annotation for each model (and alignments):
>> Yos1  Yos1-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.9   0.4   5.3e-40   9.4e-36       1      80 []       5      85 .]       5      85 .] 0.98

  Alignments for each domain:
  == domain 1  score: 121.9 bits;  conditional E-value: 5.3e-40
        Yos1  1 LgslleaalLliNaiaiLsedRfLariglssssaesafges.eeasvkakiinliaavrtlmripLiviNilvivyelvlG 80
                +g+l+++++LliNa+a+LsedRfLarig+++++ e++fg+s +++s+ka+ +nli++vrt+mripLiviN+++ivyel+lG
  EEA20115.1  5 FGRLIYVTILLINAVAVLSEDRFLARIGWGRAQPEPGFGSSyDNSSIKARTVNLITSVRTVMRIPLIVINTVIIVYELILG 85
                689************************************999**************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (85 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       322  (0.0179597); expected 358.6 (0.02)
Passed bias filter:                      187  (0.01043); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.27s 00:00:00.67 Elapsed: 00:00:00.44
# Mc/sec: 577.09
//
Query:       EEA20116.1  [L=263]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.9e-12   46.2   0.0    9.2e-12   46.0   0.0    1.0  1  Abhydrolase_6  Alpha/beta hydrolase family
    1.2e-09   37.8   0.0    2.5e-09   36.8   0.0    1.5  1  Hydrolase_4    Serine aminopeptidase, S33
    4.7e-07   30.2   0.0    7.3e-07   29.5   0.0    1.3  1  Thioesterase   Thioesterase domain
    7.2e-06   26.0   0.5      0.096   12.5   0.0    2.1  2  Abhydrolase_2  Phospholipase/Carboxylesterase
    3.3e-05   23.7   1.2    0.00015   21.6   0.4    2.4  2  PGAP1          PGAP1-like protein
      5e-05   23.0   0.2    0.00013   21.6   0.2    1.7  2  LIDHydrolase   Lipid-droplet associated hydrolase
     0.0014   18.4   0.7     0.0091   15.8   0.1    2.3  3  Abhydrolase_5  Alpha/beta hydrolase family
     0.0027   17.2   1.5          1    8.8   0.0    2.4  2  Peptidase_S9   Prolyl oligopeptidase family
     0.0046   16.6   0.0       0.51    9.9   0.0    2.2  2  Abhydrolase_1  alpha/beta hydrolase fold
      0.007   16.1   0.1      0.024   14.3   0.1    1.7  1  FSH1           Serine hydrolase (FSH1)
     0.0087   15.6   0.8       0.21   11.1   0.1    2.2  2  PE-PPE         PE-PPE domain
  ------ inclusion threshold ------
      0.035   13.6   0.3      0.083   12.4   0.1    1.7  2  DUF676         Putative serine esterase (DUF676)
      0.038   13.6   0.0       0.07   12.8   0.0    1.5  1  Abhydrolase_8  Alpha/beta hydrolase
      0.051   13.4   1.0       0.38   10.6   0.1    2.3  2  Lipase_3       Lipase (class 3)
      0.078   12.4   0.1        6.4    6.1   0.0    2.1  2  Peptidase_S10  Serine carboxypeptidase
      0.082   12.4   0.0       0.12   11.8   0.0    1.3  1  DUF900         Alpha/beta hydrolase of unknown function (DUF9
       0.23   11.0   0.5         22    4.6   0.2    2.9  3  Esterase       Putative esterase


Domain annotation for each model (and alignments):
>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.0   0.0   8.7e-15   9.2e-12       1     219 [.       6     254 ..       6     255 .. 0.69

  Alignments for each domain:
  == domain 1  score: 46.0 bits;  conditional E-value: 8.7e-15
                    EEEE--GC.....GCHHHHHHHHCCT..CEEEEE--TTS.TS-GGCS--HHHCHHH.HHHHCCTT..TTSEEEEEETCHHHHHHHHHHCC...... CS
  Abhydrolase_6   1 vlllHGagssassWlvapLaallaag..vhvlapDlpGh.Grsdpppldledladl.aalldelaagggpvvlvGHSlGGalalaaapla...... 86 
                    ++ ++G+++s+s++    L   l+++  ++v++  l ++   ++ +p + ++ a++ + ++++l ++g++vv+vGHS+GG++a++   +       
     EEA20116.1   6 IVIVPGSFTSPSAYD--TLSSILNQQygYEVIVGTLQSTsRVPPEKPATMQEDAAYfRGIIESLSNQGKDVVVVGHSYGGIVATE---SVkkvtkp 96 
                    799***********7..6655566665678899999999323344445554445556667777777*******************...44555899 PP

                    .............EEEEES-..----TTTS----TTHHHHHHTT-C........CCCH.CCH.....S-HSCCCCHHHCCCCHCHCCCGHHHHCCH CS
  Abhydrolase_6  87 ...........lvvgvlldppptalpagllaaalelllallallrl........lawl.sre.....plprlfladedadaawrarlarlaallag 157
                               +v+ +++++ + + + + ++ +  +l +++  l++        + ++ + e     +++ ++l+de+   + +  ++++  ++++
     EEA20116.1  97 erqvqgmsaggVVRVIYVASLVAQIGETAIQVIGGQLGQAINILASlctfklgdYMYFdT-EagalyLYD-GLLSDEA--LEAAGKYTTVHSTASF 188
                    999999999976666*****5555555557777777777777555555555544333323.246674555.9999999..8888888888888888 PP

                    HCHTTCCHHTT-TTGCEEECTT-CHHHHCHHCCCH.......STTEEETCE...SSS-HHHHSHHHHHH CS
  Abhydrolase_6 158 lgllpaaawadlpvpllvlggeDplvprllerlla.......qagarlpvvlpgaGHlphleepdevae 219
                    l++ +  a+ ++pv++ ++ ++D +vp  l+r          ++ +++ ++  + GH+p+  +p+ +a+
     EEA20116.1 189 LDPSTNLAVDHVPVTY-IHTEKDIIVP--LQRQQEivetlksRNAKEVSTITINEGHMPQKLAPEVIAK 254
                    8877777888888888.8556666777..444444223333433333338888******9988888886 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.8   0.0   2.4e-12   2.5e-09       4     223 ..       3     232 ..       1     240 [. 0.77

  Alignments for each domain:
  == domain 1  score: 36.8 bits;  conditional E-value: 2.4e-12
  Hydrolase_4   4 kavvvlvHGlaehsgryaelaeaLaaq.GfavyalDhrGhGrsegkrghvpsfddyvdDlaafvekvk.eehpelplfllGhSmGGliallyl...lr 96 
                  k ++v+v+G   + ++y+ l   L++q G++v+     G  +s   r+  ++  ++ +D+a f   ++   ++++ ++++GhS GG++a++ +   ++
   EEA20116.1   3 KPTIVIVPGSFTSPSAYDTLSSILNQQyGYEVIV----GTLQS-TSRVPPEKPATMQEDAAYFRGIIEsLSNQGKDVVVVGHSYGGIVATESVkkvTK 95 
                  6788999999999999999999998876888875....66677.88888899999********999997778888******************77555 PP

  Hydrolase_4  97 ypdkvaglilsaPalkikaklkappllkl....llkllgkllpklqv....snnlkadslsrdpevvaayeadplv.hgkitvrlllelldamkrlee 185
                   +++v+g+  ++ ++++  ++ a+ ++++    ++ + g+l + + +       ++ d++  d+e  a+y  d l+  +++ +   ++ +  +++ ++
   EEA20116.1  96 PERQVQGMS-AGGVVRVI-YV-ASLVAQIgetaIQVIGGQLGQAINIlaslCTFKLGDYMYFDTEAGALYLYDGLLsDEALEAAGKYTTVHSTASFLD 190
                  566677653.34444443.22.23333321112222222222333335556556899***************************************** PP

  Hydrolase_4 186 raakit...lPllllhGeaDkvvdpeasrelyerlgsk.dkt 223
                    +++    +P+  +h e+D +v+ + ++e++e+l+s+  k+
   EEA20116.1 191 PSTNLAvdhVPVTYIHTEKDIIVPLQRQQEIVETLKSRnAKE 232
                  ***999999***************************994454 PP

>> Thioesterase  Thioesterase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.5   0.0     7e-10   7.3e-07       2      97 ..       5     103 ..       4     108 .. 0.86

  Alignments for each domain:
  == domain 1  score: 29.5 bits;  conditional E-value: 7e-10
                   EEEEE--TTCCSGGGHHHHHHCTTC.EEEEEEECSTTST.SHHHCTTCHHHHHHHHHHHHHHH-SSS.SEEEEEETHHHHHHHHHHHHHHHCT-SEE CS
  Thioesterase   2 pLflfppagGsasvfrslasklsdp.vvevlavqlpgre.rdepplesieelaaeyaealrqiqpeg.PyalfGhSlGgllAfevArqLesqGlavk 95 
                   +++++p+++ s s++ +l+s l+++   ev++ +l + +  + + + +++e aa++  ++++   +g  ++++GhS+Gg++A e  ++  +  ++v+
    EEA20116.1   5 TIVIVPGSFTSPSAYDTLSSILNQQyGYEVIVGTLQSTSrVPPEKPATMQEDAAYFRGIIESLSNQGkDVVVVGHSYGGIVATESVKKVTKPERQVQ 101
                   7899*********************966666666666655777788899999**************99**************998888777777777 PP

                   EE CS
  Thioesterase  96 sl 97 
                   ++
    EEA20116.1 102 GM 103
                   66 PP

>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.9   0.1   0.00013      0.14     104     143 ..      71     110 ..      38     145 .. 0.72
   2 !   12.5   0.0   9.1e-05     0.096     150     192 ..     192     236 ..     159     257 .. 0.68

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00013
                    GGGEEEEEETHHHHHHHHHHHT-SS--SEEEEES---TTG CS
  Abhydrolase_2 104 ssriiigGFSqGaalalylaltlpkklggivafsgalpls 143
                     ++++++G S G+++a++++++ +k+ + + ++s   + +
     EEA20116.1  71 GKDVVVVGHSYGGIVATESVKKVTKPERQVQGMSAGGVVR 110
                    479**********************999999998654444 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 9.1e-05
                    S-GGG.GG-EEEEEEETT-SSS-HHHHHHHHHHHHTTS-.GEEEE CS
  Abhydrolase_2 150 atavt.kklpilqiHgeeDpvvplalgkaakevlkkllk.kvelk 192
                     t+++  ++p+  iH e+D +vpl+ +++  e lk+ +  +v+  
     EEA20116.1 192 STNLAvDHVPVTYIHTEKDIIVPLQRQQEIVETLKSRNAkEVSTI 236
                    2333324899*************************9998444333 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.6   0.4   1.4e-07   0.00015      65     110 ..      53      91 ..       1     103 [. 0.77
   2 ?   -1.9   0.0       2.1   2.3e+03     172     203 ..     207     239 ..     174     253 .. 0.57

  Alignments for each domain:
  == domain 1  score: 21.6 bits;  conditional E-value: 1.4e-07
       PGAP1  65 lldqaeylndaIkyIlslysssekeptsviliGHSmGGivaraalt 110
                 +++ a y   +I+       s +++ ++v+++GHS+GGiva   ++
  EEA20116.1  53 MQEDAAYFRGIIE-------SLSNQGKDVVVVGHSYGGIVATESVK 91 
                 5555555444444.......4568899**************76665 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 2.1
       PGAP1 172 girdsmvpae.yssleelvpstnglsvattsip 203
                   +d++vp + ++ + e+++s n   v t +i+
  EEA20116.1 207 TEKDIIVPLQrQQEIVETLKSRNAKEVSTITIN 239
                 344444443212223333445555555555554 PP

>> LIDHydrolase  Lipid-droplet associated hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.6   0.2   1.3e-07   0.00013       2     149 ..       3     146 ..       2     222 .. 0.86
   2 ?   -0.5   0.0      0.71   7.5e+02     226     252 ..     202     231 ..     179     243 .. 0.76

  Alignments for each domain:
  == domain 1  score: 21.6 bits;  conditional E-value: 1.3e-07
  LIDHydrolase   2 kilivlipGNPGlveFYetFlsllseklnpelevlgishaGfeleeeekeakenekvfsLedQiehkedflkellekaksekdvklilvGHSvGaYi 98 
                   k++iv++pG     + Y t  s l+++    +ev++ ++++ +  + e       k  ++++   + + ++++l +     +++++++vGHS G  +
    EEA20116.1   3 KPTIVIVPGSFTSPSAYDTLSSILNQQ--YGYEVIVGTLQSTSRVPPE-------KPATMQEDAAYFRGIIESLSN-----QGKDVVVVGHSYGGIV 85 
                   6889999999999999***99999999..7899999999888888877.......999**************9864.....99************** PP

  LIDHydrolase  99 alevlkrlsers..........ikkvvlLfPtiediakSpngkkltkllaylpflalvvgl 149
                   a e +k++ + +          + +v+ +  ++ +i ++  + +  +l   +++la ++ +
    EEA20116.1  86 ATESVKKVTKPErqvqgmsaggVVRVIYVASLVAQIGETAIQVIGGQLGQAINILASLCTF 146
                   ******998877889*******999999999999999999999999998888888766655 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.71
  LIDHydrolase 226 lvfyfgkkDhWvpeetrdelkellge...e 252
                   ++ +  +kD  vp + ++e++e+l++   +
    EEA20116.1 202 VTYIHTEKDIIVPLQRQQEIVETLKSrnaK 231
                   667788999999999999999999885431 PP

>> Abhydrolase_5  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.1   8.7e-06    0.0091       2      77 ..       6      92 ..       5     105 .. 0.74
   2 ?   -0.7   0.0         1   1.1e+03      59      76 ..      98     115 ..      87     124 .. 0.72
   3 ?   -0.0   0.0      0.62   6.5e+02      89     133 ..     187     233 ..     166     244 .. 0.72

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 8.7e-06
  Abhydrolase_5  2 lifYpGakveaesYaelaeklaks.Gyevvlvkl.......Plnlavlgknka..eeiikeapkl.ekfvvgGhslGGvvasrfaae 77
                   +++ pG++  + +Y +l++ l ++ Gyev++  l       P   a + +++a  + ii++  ++ ++ vv Ghs GG+va++ +++
     EEA20116.1  6 IVIVPGSFTSPSAYDTLSSILNQQyGYEVIVGTLqstsrvpPEKPATMQEDAAyfRGIIESLSNQgKDVVVVGHSYGGIVATESVKK 92
                   78889*************9998655***9985432233334677899999998445799987665267999*********9987764 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 1
  Abhydrolase_5  59 fvvgGhslGGvvasrfaa 76 
                      v G s GGvv   ++a
     EEA20116.1  98 RQVQGMSAGGVVRVIYVA 115
                    458999*****9877765 PP

  == domain 3  score: -0.0 bits;  conditional E-value: 0.62
  Abhydrolase_5  89 sYPe.kdelselskkvlsivgteDgvlnvkslekakkfl.pkdtkvv 133
                    s+ +   +l    ++v  i +++D +++ ++ ++  ++l ++++k v
     EEA20116.1 187 SFLDpSTNLAVDHVPVTYIHTEKDIIVPLQRQQEIVETLkSRNAKEV 233
                    55444456777788899999999999999999988887734555544 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.8   0.5     0.004       4.2      64     101 ..      72     111 ..      57     124 .. 0.75
   2 !    8.8   0.0   0.00098         1     129     187 ..     184     243 ..     159     255 .. 0.82

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.004
                   GGEEEEEETHHHHHHHHHHH..H-GGG-SEEEEESE---C CS
  Peptidase_S9  64 erlaitGgSyGGyltgaaln..qrpdlFkaavaevpvvdv 101
                   + +++ G+SyGG ++   +    +p++   ++++ +vv v
    EEA20116.1  72 KDVVVVGHSYGGIVATESVKkvTKPERQVQGMSAGGVVRV 111
                   789*********9988777644566666666666666655 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.00098
                   HHHHHH-CGGG--.---EEEEEEETT-SSS-THHHHHHHHHHH--S-SEEEEEETTS-SS CS
  Peptidase_S9 129 kelspyspldnvk.aypplLlihGlaDdrvppaealklvaaLqkkgknvlllifpdegHg 187
                   +++s ++p +n++   +p+  ih ++D  vp++   ++v++L++++ +    i  +egH 
    EEA20116.1 184 STASFLDPSTNLAvDHVPVTYIHTEKDIIVPLQRQQEIVETLKSRNAKEVSTITINEGHM 243
                   45556666677667999**************************99999888888999994 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.9   0.0   0.00049      0.51      71      89 ..      70      88 ..       4     105 .. 0.74
   2 ?    5.1   0.0     0.014        15     212     251 ..     197     243 ..     146     249 .. 0.67

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00049
                   TTSSEEEEEETHHHHHHHH CS
  Abhydrolase_1 71 gddkltlvGhSmGGmiala 89
                     + +++vGhS+GG +a++
     EEA20116.1 70 QGKDVVVVGHSYGGIVATE 88
                   345677********99987 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.014
                    S...EEEEEEETTCSSSCHHHHHHHHHCHTS....EEEEEEETCSSS CS
  Abhydrolase_1 212 a...ptlvisgtsDplvppkaledlaqllpk....krlvvisdagHl 251
                    +   p+ +i++++D +vp + + ++ + l++    +   +  ++gH+
     EEA20116.1 197 VdhvPVTYIHTEKDIIVPLQRQQEIVETLKSrnakEVSTITINEGHM 243
                    2446***************7766666664443443333344566666 PP

>> FSH1  Serine hydrolase (FSH1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.1   2.2e-05     0.024      93     200 ..      63     242 ..      45     248 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2.2e-05
        FSH1  93 vkdyikengpfdGiiGFSqGaalaallaslleellkea................................shpslkfailvsGfkleepk......... 150
                 + + ++++g  + ++G S G+++a+  ++++ + +++                                   + ++++  ++ fkl + +         
  EEA20116.1  63 IIESLSNQGKDVVVVGHSYGGIVATESVKKVTKPERQVqgmsaggvvrviyvaslvaqigetaiqviggqLGQAINILASLCTFKLGDYMyfdteagal 161
                 556677788888899999999999999999998888778888888888887777777777777888777655566777777888887777999999999 PP

        FSH1 151 .......................yeeyy.eedki...qtptLhvlGelDtvvdeerseaLaeafkns....skvlkHpggH 200
                                         +++   ++++    +p+ +++ e+D +v+ +r ++++e+ k++      +++ + gH
  EEA20116.1 162 ylydgllsdealeaagkyttvhsTASFLdPSTNLavdHVPVTYIHTEKDIIVPLQRQQEIVETLKSRnakeVSTITINEGH 242
                 99999998888888888777654333336444446789***************************9887665666777777 PP

>> PE-PPE  PE-PPE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.1   0.1    0.0002      0.21      35      85 ..      59     104 ..       3     132 .. 0.76
   2 ?    3.2   0.1     0.054        57     155     196 ..     202     244 ..     196     260 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.0002
      PE-PPE  35 nLeaairaelaagekvvvfGySqgalvasnekarlaalsepaapdqlsfvl 85 
                  +   i++  + g++vvv+G S g++va++  ++ ++   p++  q++ + 
  EEA20116.1  59 YFRGIIESLSNQGKDVVVVGHSYGGIVATESVKKVTK---PER--QVQGMS 104
                 444555666669*******************999988...333..444444 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.054
      PE-PPE 155 ialvHtnyetevaeqlpanirtt.vnsrgakttyylipteelP 196
                 + ++Ht+ +  v+ q +++i +t  + + ++ +++ i++ ++P
  EEA20116.1 202 VTYIHTEKDIIVPLQRQQEIVETlKSRNAKEVSTITINEGHMP 244
                 5799*999999999*********5555556789999*999999 PP

>> DUF676  Putative serine esterase (DUF676)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   7.9e-05     0.083      68     106 ..      61      99 ..      53     119 .. 0.76
   2 ?   -2.0   0.0       1.9   2.1e+03      54      82 ..     209     234 ..     201     253 .. 0.64

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 7.9e-05
      DUF676  68 levvkkkkdknkkiSfvghSlGgliaraaiaklkekemt 106
                 + ++++ +++ k + +vghS Gg++a+  + k+ + e +
  EEA20116.1  61 RGIIESLSNQGKDVVVVGHSYGGIVATESVKKVTKPERQ 99 
                 556677777767799****************99987763 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.9
      DUF676  54 kgidvlgerlaeevlevvkkkkdknkkiS 82 
                 k+i v  +r  +e++e++k+++ k   +S
  EEA20116.1 209 KDIIVPLQR-QQEIVETLKSRNAK--EVS 234
                 555554444.46777777777766..333 PP

>> Abhydrolase_8  Alpha/beta hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   6.6e-05      0.07      97     131 ..      59      94 ..      35     108 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 6.6e-05
  Abhydrolase_8  97 llrdl.ratsvpgqhlallgHSYGSlvaslAlddaa 131
                    + r++ ++ s+ g+ + ++gHSYG +va+  +++++
     EEA20116.1  59 YFRGIiESLSNQGKDVVVVGHSYGGIVATESVKKVT 94 
                    4444414556899***************99988854 PP

>> Lipase_3  Lipase (class 3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.1   0.00036      0.38      52      80 ..      61      87 ..      20     103 .. 0.78
   2 ?    0.9   0.1      0.36   3.8e+02      55      84 ..     114     143 ..     104     151 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00036
                HHHHHHHHHHTT-EEEEEEEETHHHHHHH CS
    Lipase_3 52 lkelkrllekypeysivvtGHSLGgalAl 80
                +  +++l ++ +   +vv+GHS Gg +A+
  EEA20116.1 61 RGIIESLSNQGK--DVVVVGHSYGGIVAT 87
                555666777777..9**********9986 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.36
                 HHHHHHHTT-EEEEEEEETHHHHHHHHHHH CS
    Lipase_3  55 lkrllekypeysivvtGHSLGgalAlLaal 84 
                 + +l+++  e+ i v G  LG a+ +La+l
  EEA20116.1 114 VASLVAQIGETAIQVIGGQLGQAINILASL 143
                 5679999999*************9999976 PP

>> Peptidase_S10  Serine carboxypeptidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0     0.021        23     133     162 ..      69      98 ..      58     108 .. 0.83
   2 ?    6.1   0.0    0.0061       6.4     313     370 ..     181     238 ..     170     255 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.021
                    GTTSEEEEEEETTHHHHHHHHHHHHHTHCC CS
  Peptidase_S10 133 yksrdfyitGESYaGhyvPalakeilkknk 162
                     + +d+ ++G SY+G++    +k+++k + 
     EEA20116.1  69 NQGKDVVVVGHSYGGIVATESVKKVTKPER 98 
                    47799***********99888888877655 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.0061
                    TCCC-SBCHHHHHHHHHTT-EEEEEEETT-STT-HHHHHHHHHHTECTTECCSCCCEE CS
  Peptidase_S10 313 eddisksveeileellesglrvliynGdvDlicnvlgteawikklelsgkkefrpwev 370
                    + +++ s+ +  ++l  ++++v+ +  ++D+i+++  +++++++l+ + +ke ++ + 
     EEA20116.1 181 TVHSTASFLDPSTNLAVDHVPVTYIHTEKDIIVPLQRQQEIVETLKSRNAKEVSTITI 238
                    4566677888888999999***************************999999887766 PP

>> DUF900  Alpha/beta hydrolase of unknown function (DUF900)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   0.00012      0.12      79     132 ..      59     112 ..      48     129 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00012
      DUF900  79 alekllrylatkksakkihllaHSmGtwlvlealrqlaieade.pavea.kikevi 132
                  +  +++ l ++   k++ ++ HS G  +++e ++++ + +++ +++ a  + +vi
  EEA20116.1  59 YFRGIIESLSNQ--GKDVVVVGHSYGGIVATESVKKVTKPERQvQGMSAgGVVRVI 112
                 567788888888..9*********************99877763333335444555 PP

>> Esterase  Putative esterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.2     0.021        22     116     129 ..      72      86 ..      62      93 .. 0.80
   2 ?   -0.3   0.0      0.66   6.9e+02     111     132 ..      93     113 ..      87     117 .. 0.76
   3 ?    2.8   0.0     0.074        78     133     198 ..     172     248 ..     156     262 .. 0.69

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.021
                 C.EEEEEETHHHHHH CS
    Esterase 116 g.ravaGqSmGGlgA 129
                 +  +v+G+S GG +A
  EEA20116.1  72 KdVVVVGHSYGGIVA 86 
                 2499********998 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.66
                 SEECCCEEEEEETHHHHHHHHH CS
    Esterase 111 rtapdgravaGqSmGGlgALil 132
                  t+p+ r v G S GG++ +i+
  EEA20116.1  93 VTKPE-RQVQGMSAGGVVRVIY 113
                 45555.99********986665 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.074
                 HHCSTTTCCEEEEES--S-CC................HCHHHCTTCCHHHCC-CCCCHCHHCHTTSEEEEEEEECTTBCCCH CS
    Esterase 133 alkhpdrFgsvssfSpivnps................namWgqeekeawqendpvllakelsaslkalriyldvGtseddlg 198
                 al++ ++++ v s + +++ps                + ++        q+++++++  ++ + ++  +i +  G  +++l+
  EEA20116.1 172 ALEAAGKYTTVHSTASFLDPStnlavdhvpvtyihteKDIIV-----PLQRQQEIVETLKSRNAKEVSTITINEGHMPQKLA 248
                 788888999999999999999777777665444444333332.....24556666666666777777777777777776554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (263 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       815  (0.0454571); expected 358.6 (0.02)
Passed bias filter:                      602  (0.0335769); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              17  [number of targets reported over threshold]
# CPU time: 0.67u 0.39s 00:00:01.06 Elapsed: 00:00:00.58
# Mc/sec: 1372.34
//
Query:       EEA20117.1  [L=658]
Description: hypothetical protein PMAA_039800 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.14   12.5   0.0       0.36   11.1   0.0    1.7  1  AAA_22    AAA domain


Domain annotation for each model (and alignments):
>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0     2e-05      0.36      14     113 ..      99     236 ..      93     268 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 2e-05
      AAA_22  14 sGtGKTtllrrlleqldeeakaee....................erpevvfvtlpsst.........sskdl.lrellralglelkaerlsseell.ea 81 
                 +GtGK++ +++l++++    + ++                    e+p v+++t+ ++t          +k +  r+ll+ lg++ ++   + ++ + e 
  EEA20117.1  99 AGTGKSRNAAELHKTAFDCFNGTHfpkndddelarredelarllENPFVFHITMENGTsintsrdenPWKAIgSRMLLQLLGEPDNT---EWHQPFpED 194
                 6999999999999998555444448999999999999999999999999988888888888777778999999999******99999...444444444 PP

      AAA_22  82 leqalrarav....ielliiDEaqhlr..s....eealeeLr 113
                 + + + ++ +      ++i+D  ++++       +e l++L 
  EEA20117.1 195 VLDSVINQCDletrAIFIIVDGLHNVTrfGedawDETLTNLG 236
                 4444444444455479*********96551545555555553 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (658 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       550  (0.0306766); expected 358.6 (0.02)
Passed bias filter:                      492  (0.0274416); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.81u 0.38s 00:00:01.19 Elapsed: 00:00:00.60
# Mc/sec: 3301.97
//
Query:       EEA20118.1  [L=730]
Description: ubiquitin hydrolase CreB [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.7e-58  196.0   0.4    1.5e-57  195.0   0.4    1.5  1  UCH            Ubiquitin carboxyl-terminal hydrolase
    1.1e-27   97.5   2.9    2.5e-20   73.3   0.3    2.3  2  UCH_1          Ubiquitin carboxyl-terminal hydrolase
     0.0011   18.6   3.6      0.035   13.6   2.3    3.0  3  Peptidase_C98  Ubiquitin-specific peptidase-like, SUMO isopep
  ------ inclusion threshold ------
        7.7    6.8  19.0        1.1    9.6  12.2    2.5  2  Vfa1           AAA-ATPase Vps4-associated protein 1


Domain annotation for each model (and alignments):
>> UCH  Ubiquitin carboxyl-terminal hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  195.0   0.4   3.4e-61   1.5e-57       1     257 []      18     443 ..      18     443 .. 0.89

  Alignments for each domain:
  == domain 1  score: 195.0 bits;  conditional E-value: 3.4e-61
                 -EES-SSSTHHHHHHHHHHHTSHHHHHHHHTCHHCCSSTCCCCC....................................................... CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....................................................... RF
         UCH   1 tGlsNlGntCymnsvlQcLfsipelrdyllsleevkkesrnkke....................................................... 44 
                 +G++N GntCy+ns+lQcL+  +++r+ ++++ +++ +++ ++                                                        
  EEA20118.1  18 FGMENYGNTCYCNSILQCLYYSAPFRESVINYPKRTPIESLETAlaknlkyqspeaffeaeaaaakakhtagqsssrnagvapaqpqkpedkdspeykk 116
                 69************************8888877777777666667888888888888888888888888888888888888888888888888888888 PP

                 ............-.TT.TTS.TTHHHHHHHHHHHHHH..SH-CCEE--HHHHHHHHHHSGGGTSSSTCEHHHHHHHHHHHHHHHHCC............ CS
                 ............xxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............ RF
         UCH  45 ............lnesnplgkkgelakalkdlfkell..kskskavsPkklkktlsklaksfsgykqqDaqEflaflLdqlhedlnr............ 117
                              ++s + g+++ l+++lkd+f++++  +sk  +v P++++++l++++++f++ + qDa+Efl+ lL+++  ++++            
  EEA20118.1 117 kvaiqtlplletKDNSASYGMSESLFTSLKDIFESVVgsQSKLGIVRPHHFLEVLRRENEMFRTAMHQDAHEFLNLLLNEVVTNVEAesfkqienfpad 215
                 888877776554366667777778*************8877888******************************************************* PP

                 ...................HCCCHHH....HHHCCCTTSHHHHHH-EEEEE................................................ CS
                 ...................xxxxxxx....xxxxxxxxxxxxxxxxxxxxx................................................ RF
         UCH 118 ...................evaeekw....kkhlkrndslitdlfegqlks................................................ 145
                                      +         +++ + + ++++lfeg+l+s                                                
  EEA20118.1 216 ntdseqtvalmdsstpstrT-Q---VngstGSKTPNTTRWVHELFEGTLTSetqcltcekvsqrdevfldlsvdleqhssvtsclrkfsaeemlcernk 310
                 *************9987531.2...12345777778889************************************************************ PP

                 ..............EEEEEEB-SEEEEEEESEEETEE...EEE--SEEB--SEEE-GGGBSS-BTTS-TCS-BEEEEEEEEEES.CTTSEEEEEEEECT CS
                 ..............xxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxx RF
         UCH 146 ..............klklkrlPeiLiihlkRfsynss...ksKlntkvefpeeldlssylaeekkkkteekkkYeLiavvvHsG.slssGHYvayikne 226
                               ++k+krlP+iL +hlkRf+y+++    +Kl ++v +p  l l +++++ ++++    + YeL+avvvH+G ++ +GHYv++ik +
  EEA20118.1 311 fhcdncgglqeaekRMKIKRLPKILALHLKRFKYTEDlqrLQKLFHRVVYPYHLRLFNTTDDAEDPD----RLYELYAVVVHIGgGPYHGHYVSIIK-T 404
                 **********************************8888899***************99888666666....45************************.6 PP

                 TTTEEEEEETTEEEEE-HHCCCTT.........CEEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxx.........xxxxxxx RF
         UCH 227 kngkWykydDetvkevkeeeevls.........sayiLfY 257
                 ++  W+ +dDe v++v+++  v +          ay+LfY
  EEA20118.1 405 EDRGWLLFDDEMVEPVDKS-YVHNffgdrpglaCAYVLFY 443
                 6777*************87.6777888899999******* PP

>> UCH_1  Ubiquitin carboxyl-terminal hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4   0.1   4.3e-09   1.9e-05       2      30 ..      19      47 ..      18      58 .. 0.92
   2 !   73.3   0.3   5.6e-24   2.5e-20     124     318 ..     208     415 ..     110     417 .. 0.66

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 4.3e-09
                xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       UCH_1  2 GLEnhivnsYlNslLQvlyfipplrnlal 30
                G+En  +++Y+Ns+LQ+ly+  p+r+ ++
  EEA20118.1 19 GMENYGNTCYCNSILQCLYYSAPFRESVI 47
                9************************7765 PP

  == domain 2  score: 73.3 bits;  conditional E-value: 5.6e-24
                 x.....................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       UCH_1 124 s.....................................seeesaieqllgtkaettirclkCgseksrksstlvldlkyPkpsnekkeakvtfasilks 185
                 +                                      +++  +++l++ +++++++cl+C++ ++r++++l l++    +      +++++ s+l++
  EEA20118.1 208 QienfpadntdseqtvalmdsstpstrtqvngstgsktPNTTRWVHELFEGTLTSETQCLTCEKVSQRDEVFLDLSVDL--E------QHSSVTSCLRK 298
                 13333333333344444444444444444455677666677788999**************************987644..3......33566777777 PP

                 xxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       UCH_1 186 sler...ekttrawCekCkryqpteqrktvknlPpvLalnakle.eeeelelwktknwlpleiklsldedknleeklkeerekakaekeikvYeLqsvv 280
                 +  +    + ++  C++C   q  e+r ++k+lP++Lal++k++  +e+l+       l++ ++  +++ +     l+  +++++ae+  + YeL +vv
  EEA20118.1 299 FSAEemlCERNKFHCDNCGGLQEAEKRMKIKRLPKILALHLKRFkYTEDLQR------LQKLFHRVVYPYH-----LRLFNTTDDAEDPDRLYELYAVV 386
                 666633336799******************************9854554444......4444444444433.....3333344455677899******* PP

                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       UCH_1 281 vhigdskesghLvslvkvaekelerdppesqWylFNDf 318
                 vhig +  +gh+vs++k +         +  W+lF+D 
  EEA20118.1 387 VHIGGGPYHGHYVSIIKTE---------DRGWLLFDDE 415
                 ****7778*********63.........348******5 PP

>> Peptidase_C98  Ubiquitin-specific peptidase-like, SUMO isopeptidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0      0.28   1.3e+03       6      36 ..      22      52 ..      20     105 .. 0.66
   2 !   13.6   2.3   7.8e-06     0.035     118     217 ..     249     360 ..     246     364 .. 0.70
   3 ?    2.1   0.0     0.025   1.1e+02     226     248 ..     392     414 ..     376     427 .. 0.74

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.28
  Peptidase_C98  6 nkenlCWLDsllvalvhletlkkalselese 36
                   n  n C+ +s+l  l ++  +++++ +  ++
     EEA20118.1 22 NYGNTCYCNSILQCLYYSAPFRESVINYPKR 52
                   78899************99999998554333 PP

  == domain 2  score: 13.6 bits;  conditional E-value: 7.8e-06
  Peptidase_C98 118 dslaeklfkssfswefeCseCgvkkke.rve....ktl...ttftnvvpdwhplnA...vhlapCnkCkk.keqrrkmvlekvpsvlmlHFveGLp 201
                     +++++lf+ +++ e +C +C+  +++ +v       l   ++ t+ +  ++  +     +   C++C   +e +++m+++++p++l+lH      
     EEA20118.1 249 TRWVHELFEGTLTSETQCLTCEKVSQRdEVFldlsVDLeqhSSVTSCLRKFSAEEMlceRNKFHCDNCGGlQEAEKRMKIKRLPKILALHLKRFKY 344
                    579999***************87665514331111233111456666667765443111455689999863677899**************99999 PP

  Peptidase_C98 202 hndlekysfefegkqY 217
                    ++dl++++  f+   Y
     EEA20118.1 345 TEDLQRLQKLFHRVVY 360
                    9999999888887776 PP

  == domain 3  score: 2.1 bits;  conditional E-value: 0.025
  Peptidase_C98 226 kkelkHFvtwirnsdgsWlecDD 248
                       + H+v+ i+++d  Wl +DD
     EEA20118.1 392 GPYHGHYVSIIKTEDRGWLLFDD 414
                    44568*****************9 PP

>> Vfa1  AAA-ATPase Vps4-associated protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.5      0.19   8.5e+02     108     149 ..      86     141 ..      49     149 .. 0.36
   2 ?    9.6  12.2   0.00023       1.1      59     135 ..     531     606 ..     520     657 .. 0.65

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.19
        Vfa1 108 ekdkkkekek...........eeekkkelkkaeeelee......keeprvkkykLhkef 149
                 ++  ++++ +           e++ + e+kk+ +          +++ + ++y +++++
  EEA20118.1  86 HTAGQSSSRNagvapaqpqkpEDKDSPEYKKKVA---IqtlpllETKDNSASYGMSESL 141
                 1111111111111121111111111222211111...0112333344444455555555 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00023
        Vfa1  59 eeaakkkkeleeeiekvkkeyeekqkkkkekekkkkekdkkdkdkkkekekdkkkekekeeekkkelkkaeeeleek 135
                 +++a+kk e++++ e+ k+e e+k ++k++++++k  k k+ ++k ke+ k +++e ++  e++k++k++e++++++
  EEA20118.1 531 NTEASKKAEVQSRKERAKEEKERKAAEKEKEKADK-LKRKELEAKRKEDLKREDAEMKAVLELSKATKAEEDRKSST 606
                 55678888899999999988888877776544444.33445555555555555555555444444444444443331 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (730 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2123  (0.118412); expected 358.6 (0.02)
Passed bias filter:                      729  (0.0406604); expected 358.6 (0.02)
Passed Vit filter:                       126  (0.00702772); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.99u 0.41s 00:00:01.40 Elapsed: 00:00:00.59
# Mc/sec: 3714.43
//
Query:       EEA20119.1  [L=615]
Description: histidyl-tRNA synthetase, mitochondrial precursor [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.9e-34  119.3   0.0    2.3e-28   99.4   0.0    2.1  2  tRNA-synt_His    Histidyl-tRNA synthetase
    6.7e-13   48.6   0.0    1.4e-12   47.5   0.0    1.6  1  HGTP_anticodon   Anticodon binding domain
    3.9e-05   23.7   0.0    7.3e-05   22.8   0.0    1.5  1  tRNA-synt_2b     tRNA synthetase class II core domain (G, H, 
      0.006   16.1   0.0      0.011   15.3   0.0    1.3  1  HGTP_anticodon2  Anticodon binding domain of tRNAs


Domain annotation for each model (and alignments):
>> tRNA-synt_His  Histidyl-tRNA synthetase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.4   0.0     5e-32   2.3e-28       1     277 [.      89     374 ..      89     380 .. 0.85
   2 !   18.0   0.0   3.2e-07    0.0014     280     310 .]     415     447 ..     409     447 .. 0.92

  Alignments for each domain:
  == domain 1  score: 99.4 bits;  conditional E-value: 5e-32
                    T---EETCHHHHHHHHHHHHHHHHHHTT-EEEE--SEEEHHHHCTTSTCCHHHS-EEE-TTSSEEEE-SSSHHHHHHHHHHHHHTSS-EEEEEEEE CS
  tRNA-synt_His   1 glrdllpeeaekieelrrrlldlfeswGYelVspPllEyldslltgagedldqtfklvDqsgrllglRaDiTpqvaRiaahrlnrerplRlcYaGs 96 
                    g+rd   ++   + ++ ++++++f+++G     +P++E  + l  + ged++ ++ l Dq g+  +lR D+T+  aR  a +   +++ R++ a +
     EEA20119.1  89 GTRDWSGADTLIRDRIFSTITNVFRRHGGTALDTPVFELREILAGKYGEDSKLIYDLQDQGGEICSLRYDLTVPFARWLAMNPDIRSIKRYHIA-K 183
                    567777777788899999*****************************************************************99999998865.6 PP

                    EE.ESS-SS.TT--CCEEEEEEEEESS-..SHHHHHHHHHHHHHHHHHHCT.SSSEEEEEEETCHHHHHHHHTT--HHHHHHHHHHHHCT-HHHH. CS
  tRNA-synt_His  97 vl.rtrpdg.lgrsreplQvGaEliGae..gleadlEvlslllealeaaag.vkelrldlghvglvralleaaglsesleeallaalarkdlael. 186
                    v+ r +p+   gr re++Q+   + Ga+   +  d+Evl+++ e++e  +g   +++++++h ++++ ++e +g+++++ + + +a+++ d a   
     EEA20119.1 184 VYrRDQPAVaKGRMREFYQCDFDIAGANfdPMVPDAEVLKVINEVFE-DLGwQGKFTIKINHRKVLDGMFEVCGVPQDKIRPISSAVDKLDKAPWa 278
                    6615555554579**************8756677************8.9996799*******************************9999966441 PP

                    ...HHHHHCCTTHHHCCHCC....HCCHCCCHHHHCH..CCHCTHHHHHHHHHHHHHHHHHHHHHHHH-TTEEE-TT--TTTTT--SEEEEEEETT CS
  tRNA-synt_His 187 ...kelaaeaglkealrellkal.elygdaevleeal..ealaaapalqaaldeleelaallealakpevrvtlDlaelrgyeYytGlvFaayaeg 276
                       ke+++e+gl++a+++ ++++ + +g+++  +e+l  e+l a+ a+++ ++e+  l+++lea++    ++++Dl++ rg++YytG+++++++eg
     EEA20119.1 279 dvrKEMVEEKGLDAAVADKIEKYvSKKGRKDLYAELLkdEELMANAAAKQGIEEMGLLMDYLEAFG-VLDTISFDLSLARGLDYYTGVIYEVVTEG 373
                    1126789999*************6666665544444422457777778888888888888888887.569***********************998 PP

                    - CS
  tRNA-synt_His 277 v 277
                    +
     EEA20119.1 374 S 374
                    6 PP

  == domain 2  score: 18.0 bits;  conditional E-value: 3.2e-07
                    -SEEEEEECTTTGGG..T---EEEEEEEEHHHH CS
  tRNA-synt_His 280 aiarGGrYdelgaaf..grarpAtGfsldleal 310
                     ia GGrYd+l+++f  +++ p++G s+ ++++
     EEA20119.1 415 SIAAGGRYDNLVGMFspKAQIPCVGISFGVDRI 447
                    69*************9889**********9986 PP

>> HGTP_anticodon  Anticodon binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.5   0.0   3.2e-16   1.4e-12       1      92 [.     469     568 ..     469     570 .. 0.92

  Alignments for each domain:
  == domain 1  score: 47.5 bits;  conditional E-value: 3.2e-16
                     SEEEEESSSS..HHHHHHHHHHHHHHHHTTTSEEEEES.SSSTHHHHHHHHHHTT-SEEEEE-HHHHHHTEEEEEET......TTCEEEEEETTH CS
  HGTP_anticodon   1 qvvviplnek..aeeleeyakklaeeLraagirveldd.snesigkkireadllgipfavvvGekelekgtvtvrdr......dtreqervslde 86 
                     +v+v++++ k  +  ++++++++++ L+aag+++e+ +  + ++ ++++ a++ gipf v++Ge+el  g+v+++++       ++e + v++++
      EEA20119.1 469 DVYVMAFGGKgfTG-MLKERMEICKTLWAAGVKAEFSYkLKPKLPQQFKAAETSGIPFGVILGEDELAAGQVKIKEMglpeghPEKEGVLVDIKN 562
                     68999999988555.999********************9**************************************999876666778****** PP

                     HHHHHH CS
  HGTP_anticodon  87 lveklk 92 
                     lv+++k
      EEA20119.1 563 LVSEIK 568
                     *99997 PP

>> tRNA-synt_2b  tRNA synthetase class II core domain (G, H, P, S and T)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8   0.0   1.6e-08   7.3e-05      37     110 ..     176     284 ..     164     484 .. 0.75

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 1.6e-08
                   EEEEEEEEEEBTTTS.TBCTTTB-SEEEEEEEEEEESGGGHHHHHHHHHHHHHHHHHHTT.SCEEEEEEGTTSC....................... CS
                   xxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....................... RF
  tRNA-synt_2b  37 lklyqiqtkyRdEks.dsrGLlRvreFhqkdgyvfhaeaslddslrdlikaisriferlglefraiielmsaks....................... 109
                   +k y+i  +yR+ ++   +G  R+reF q d  + +a+ +    +++++k+i+++fe+lg + + +i+++++k                        
    EEA20119.1 176 IKRYHIAKVYRRDQPaVAKG--RMREFYQCDFDIAGANFDPMVPDAEVLKVINEVFEDLGWQGKFTIKINHRKVldgmfevcgvpqdkirpissavd 270
                   56799*********96677*..***************988888999*****************99**999976566666666666666666655555 PP

                   .............B CS
                   .............x RF
  tRNA-synt_2b 110 .............a 110
                                +
    EEA20119.1 271 kldkapwadvrkeM 284
                   55555555555440 PP

>> HGTP_anticodon2  Anticodon binding domain of tRNAs
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   2.4e-06     0.011       5     125 ..     467     593 ..     464     614 .. 0.66

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 2.4e-06
  HGTP_anticodon2   5 RcDVlVasfdks....iLrtsgvellqeLWahnIsAdlaldasksleelvskarddgvswiviikqqnkskskekplkvksle......kkedv 88 
                       +DV+V+ f  +    +L ++++e+ ++LWa +++A++ ++ +  l +  + a++ g+ + vi  +++ +     ++k+k++       +ke v
       EEA20119.1 467 EVDVYVMAFGGKgftgML-KERMEICKTLWAAGVKAEFSYKLKPKLPQQFKAAETSGIPFGVILGEDELAA---GQVKIKEMGlpeghpEKEGV 556
                      589999999864222155.89********************9999******************99976333...45999999733222234466 PP

  HGTP_anticodon2  89 dldldelvswlkqeirerekereesaksskssaessq 125
                       +d+++lvs +k  i+++++  e+s+  +++  es++
       EEA20119.1 557 LVDIKNLVSEIKLRIDKKNQGVETSTVIATDAVESTT 593
                      6778888877777777776333333333333233333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (615 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       557  (0.031067); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.79u 0.35s 00:00:01.14 Elapsed: 00:00:00.57
# Mc/sec: 3275.59
//
Query:       EEA20120.1  [L=512]
Description: ubiquinone biosynthesis monooxgenase (Coq6), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.3e-21   75.9   0.0    6.3e-19   68.4   0.0    2.9  1  FAD_binding_3   FAD binding domain
     0.0009   18.4   0.0     0.0014   17.7   0.0    1.3  1  SE              Squalene epoxidase
     0.0015   17.7   0.1     0.0043   16.2   0.0    1.7  2  Lycopene_cycl   Lycopene cyclase protein
     0.0034   17.4   0.0     0.0058   16.6   0.0    1.3  1  NAD_binding_9   FAD-NAD(P)-binding
     0.0081   15.4   0.0      0.011   14.9   0.0    1.2  1  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
       0.01   14.7   0.0       0.14   11.0   0.0    2.3  3  Trp_halogenase  Tryptophan halogenase
      0.019   14.1   0.0      0.034   13.3   0.0    1.4  1  K_oxygenase     L-lysine 6-monooxygenase (NADPH-requiring)
      0.023   14.9   0.1      0.058   13.6   0.1    1.7  1  NAD_binding_8   NAD(P)-binding Rossmann-like domain
       0.17   11.1   0.0       0.29   10.4   0.0    1.2  1  Thi4            Thi4 family


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.4   0.0   3.1e-22   6.3e-19       2     318 ..      42     437 ..      41     452 .. 0.74

  Alignments for each domain:
  == domain 1  score: 68.4 bits;  conditional E-value: 3.1e-22
                    EEEEEE--SHHHHHHHHHHHHTTHH....EEEEESS......SSSCCSS....S--EEEHHHHHHHHHTT-HHHHHHHSEECCCCEEEEEEE.... CS
  FAD_binding_3   2 tdVlIVGaGpaGlmlallLseaGvr....vvlvekr......sttvvlp....radglnqrtmellrqlGledrilaegapnelmgealyne.... 79 
                    +dV+ VG+GpaGl l   L+   v       l+e +      +++++ +    r + l+++++  l+++G ++ + +  ++     +++ ++    
     EEA20120.1  42 YDVVCVGGGPAGLALVAALRASPVTsnlrIALIESQdlnksrTWNSPSSefsnRCSSLTPTSVSFLQKIGAWKLVDNSRVQPYHEMQVWDGQtgsk 137
                    589*****************999988888666665411111134444448899*******************999888766665666666666666 PP

                    ...........CCCCCEEEEEHHCHHCST-CEE--HHHHHHHHHHHHHHHT.EEETCSEEEECCEECCCCCCCEEE............ECCTTEEE CS
  FAD_binding_3  80 ...........lsdtpkaradlelesspervtvypqteleriLvehaeerg.lqvrfktevesleqdeegvtaevr............dketgeee 151
                               ++d+   r   ++  +++ v  +     e + +++ +  g l++  +t v s+e+  +  +   +             +++    
     EEA20120.1 138 isfdwsvdtspFEDI---RSVATMTENANLVRGLLRRIQELDESSNGSDNGsLSIFSNTMVSSIENGSQAADGPNLsawpvvslkpspASSSSVSG 230
                    666654443333333...333333334444444444444444455666788899999999999988877766544447777778887766777778 PP

                    EEEEEEEEE--GTT-HHHHHHTGGEEEEEEEEEEEEEEEEEEC.-SCCCTTC..............CEEEEECCTTEE.................. CS
  FAD_binding_3 152 tvrakYlvGaDGgrStvrktlgiefegeetvyeagvldvlfda.dlsdivep..............lvlilsaesrgv.................. 214
                     + a+ l+GaDG +S+vr+ ++i+ +g + + + gv+ +l  + ++s++ +               +                             
     EEA20120.1 231 PIAARLLIGADGINSPVRSFADITTTGWDYD-RQGVVATLSLSeEFSSLPNIrtayqrflpslggpI----------Allplpnnkatlvwstkpe 315
                    99*************************9988.66666666555577743333444544444455441..........1555555555677888888 PP

                    ..................EEEECCE.TEEEEEEEEECCE-GGGSCCCHHHHHHHHHHHHHHTTSSCEEEEEEEEEEEEEEEEESSSEETTEEE-GG CS
  FAD_binding_3 215 ..................mviPlen.tlerfyvqvearaekeersekfteeevkarlreivgektldveieevsawtvaqrvaekyrkgrvflaGD 291
                                      +   + + t+  +++ ++  aek++ +++ t++  ++  ++ + +  +  +++ + +++++ r a++y + rv l+GD
     EEA20120.1 316 naaylkslpeealvaminAAF-RLSmTDLTYMLSIDPAAEKGQHQDELTWRTQHTPQPSYIPPLVTSIQPRTTASFPLRFRHASSYISPRVALVGD 410
                    8888*******9999554222.233466789999999999************9999999999999999**************************** PP

                    GTEEE-STTSHHHHHHHHHHHHHHHHH CS
  FAD_binding_3 292 AaHihpPtgGqGlNtaiqDavnLawkL 318
                    AaH+  P +GqGlN++i D+  L + +
     EEA20120.1 411 AAHVIHPLAGQGLNLGIGDVSSLSSTI 437
                    *********************998776 PP

>> SE  Squalene epoxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0   7.1e-07    0.0014     103     175 ..     376     452 ..     345     480 .. 0.78

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 7.1e-07
          SE 103 ksfkkaleegklrsmpnkflpasknekkGlillGDalnmRHPltggGmtvalnDivllskllkpl....edlsdeek 175
                 + + ++++ ++  s p +f  as+  +  + l+GDa  + HPl g G+  ++ D+  ls +++       d+ d  +
  EEA20120.1 376 PPLVTSIQPRTTASFPLRFRHASSYISPRVALVGDAAHVIHPLAGQGLNLGIGDVSSLSSTIEYAvnhgMDIGDYLA 452
                 55667778888889999999999999*********************************999876332334444444 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   2.1e-06    0.0043       1      49 [.      43      90 ..      43     102 .. 0.76
   2 ?   -2.0   0.0       0.7   1.4e+03     253     273 ..     400     420 ..     382     437 .. 0.83

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 2.1e-06
  Lycopene_cycl  1 DvvviGaGpAglslAarl..teakpglkvvlieaspsllfpnnyvWsdefe 49
                   Dvv +G+GpAgl+l a l       +l++ lie s++l     ++W    +
     EEA20120.1 43 DVVCVGGGPAGLALVAALraSPVTSNLRIALIE-SQDL--NKSRTWNSPSS 90
                   9************97777225557799*****6.5556..47779976555 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.7
  Lycopene_cycl 253 rleqkvlaiGaaaglvhPaTG 273
                     + ++v+ +G aa ++hP  G
     EEA20120.1 400 YISPRVALVGDAAHVIHPLAG 420
                    46677999**********887 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   2.9e-06    0.0058       2      45 ..      46      88 ..      45      98 .. 0.90

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 2.9e-06
  NAD_binding_9  2 ivGaGprGlavlerLlarakkkspleitlfdpsepgagrvwrtd 45
                    vG+Gp+Gla++++L a+   +s+l+i l++ + + + r w++ 
     EEA20120.1 46 CVGGGPAGLALVAALRASP-VTSNLRIALIESQDLNKSRTWNSP 88
                   59****************6.99*************999**9986 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   5.7e-06     0.011       1      31 [.      42      79 ..      42     122 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 5.7e-06
                 CSEEEE--SHHHHHHHHHHHH....HTS-EEEEE...T CS
                 xxxxxxxxxxxxxxxxxxxxx....xxxxxxxxx...x RF
  Pyr_redox_2  1 kdvvviGgGpAGlaaaltlaq....agakvtlve...l 31
                 +dvv +GgGpAGla+   l++    ++++++l+e   l
   EEA20120.1 42 YDVVCVGGGPAGLALVAALRAspvtSNLRIALIEsqdL 79
                 69************999999988988*******75443 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   6.9e-05      0.14       1      39 [.      43      82 ..      43     112 .. 0.75
   2 ?   -3.1   0.0       1.3   2.5e+03     192     215 ..     132     155 ..     118     166 .. 0.74
   3 ?    0.7   0.0     0.092   1.8e+02     311     350 ..     398     437 ..     381     454 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 6.9e-05
                    EEEEE--SHHHH.HHHHHHHHHTTTSSEEEEEE-SSS--- CS
  Trp_halogenase  1 kivivGGGtaGw.laAaalakalkgklevtlveseeigtv 39
                    ++v vGGG+aG  l+Aa+ a  ++ +l++ l+es+++ + 
      EEA20120.1 43 DVVCVGGGPAGLaLVAALRASPVTSNLRIALIESQDLNKS 82
                    699********824455555555566********998765 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 1.3
                     ETTS-EEE-SEEEE-SGGG-IIII CS
  Trp_halogenase 192 ledgreveadlfiDcsGfrgllie 215
                      ++g ++++d  +D s f+ +   
      EEA20120.1 132 GQTGSKISFDWSVDTSPFEDIRSV 155
                     466889999999999988876555 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 0.092
                     S-SEETTEEE-CCCTEE--CCCS-HHHHHHHHHHHHHHT- CS
  Trp_halogenase 311 kqawvknvvalGlasgfvePlestsihliqaalrrLlall 350
                     +++ ++ v ++G+a+  + Pl ++++ l   ++++L +++
      EEA20120.1 398 SSYISPRVALVGDAAHVIHPLAGQGLNLGIGDVSSLSSTI 437
                     5566778889******************999999998765 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   1.7e-05     0.034       2      37 ..      41      78 ..      40      87 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.7e-05
  K_oxygenase  2 ilDligiGiGpsnLsLailleevk..kelkalflerqp 37
                 i+D++++G Gp+ L+L+++l+  +  ++l++  +e q+
   EEA20120.1 41 IYDVVCVGGGPAGLALVAALRASPvtSNLRIALIESQD 78
                 89******************999988999999999875 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   2.9e-05     0.058       1      29 [.      46      78 ..      46      79 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 2.9e-05
                   EE--SHHHHHHHHHHHCC....TEEEEEE-SSS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLaka....gfdvlllekrd 29
                   +vG+G +Gl++ ++L+      ++++ l+e++d
     EEA20120.1 46 CVGGGPAGLALVAALRASpvtsNLRIALIESQD 78
                   59**************96555699******986 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   0.00014      0.29      18      50 ..      42      77 ..      35      86 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00014
                EEEEEE--SHHHHHHHHHHHHC...TTS-EEEEESS CS
        Thi4 18 sDvvivGaGssGLtaayylakk...pdlkvailers 50
                 Dvv vG+G++GL+    l  +    +l++a++e++
  EEA20120.1 42 YDVVCVGGGPAGLALVAALRASpvtSNLRIALIESQ 77
                59**********986666655422469******985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (512 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       455  (0.0253779); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.66u 0.28s 00:00:00.94 Elapsed: 00:00:00.49
# Mc/sec: 3122.97
//
Query:       EEA20121.1  [L=470]
Description: serine/threonine-rich protein adg2 precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (470 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1216  (0.0678231); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.45
# Mc/sec: 3114.31
//
Query:       EEA20122.1  [L=189]
Description: hypothetical protein PMAA_039850 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.4e-16   59.7  10.9    3.5e-16   59.2  10.9    1.3  1  zf-LITAF-like  LITAF-like zinc ribbon domain
  ------ inclusion threshold ------
        3.1    7.9   8.9         48    4.1   8.9    2.2  1  Elf1           Transcription elongation factor Elf1 like


Domain annotation for each model (and alignments):
>> zf-LITAF-like  LITAF-like zinc ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.2  10.9   3.9e-20   3.5e-16       2      69 ..     104     171 ..     103     172 .. 0.93

  Alignments for each domain:
  == domain 1  score: 59.2 bits;  conditional E-value: 3.9e-20
  zf-LITAF-like   2 eptqvdCpaCqqrvvTsveyksgkltwllalllclfgcllccliPfcvdslkdvehyCpnCgallgty 69 
                     p+q+dCp+C++ + T+v+++ ++ t ++a+l+cl++ ++ +++P ++ + ++veh+C+nC+++++++
     EEA20122.1 104 VPAQIDCPFCHTISLTNVTKTDSSQTTIAAVLCCLCCGIITVCLPSLLGWYQNVEHRCGNCKRKVAYK 171
                    599************************99999999988777778********************9975 PP

>> Elf1  Transcription elongation factor Elf1 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   8.9    0.0054        48      16      52 ..     102     140 ..      92     180 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.0054
        Elf1  16 kklptkFdCpfCnheksvevkldkkek..iaevsCkvCg 52 
                   +p + dCpfC+  +  +v+ + +++  ia v C  C 
  EEA20122.1 102 GDVPAQIDCPFCHTISLTNVTKTDSSQttIAAVLCCLCC 140
                 5578899******99777776666555676666666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (189 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       861  (0.0480228); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.29s 00:00:00.75 Elapsed: 00:00:00.46
# Mc/sec: 1234.86
//
Query:       EEA20123.1  [L=189]
Description: hypothetical protein PMAA_039850 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.4e-16   59.7  10.9    3.5e-16   59.2  10.9    1.3  1  zf-LITAF-like  LITAF-like zinc ribbon domain
  ------ inclusion threshold ------
        3.1    7.9   8.9         48    4.1   8.9    2.2  1  Elf1           Transcription elongation factor Elf1 like


Domain annotation for each model (and alignments):
>> zf-LITAF-like  LITAF-like zinc ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.2  10.9   3.9e-20   3.5e-16       2      69 ..     104     171 ..     103     172 .. 0.93

  Alignments for each domain:
  == domain 1  score: 59.2 bits;  conditional E-value: 3.9e-20
  zf-LITAF-like   2 eptqvdCpaCqqrvvTsveyksgkltwllalllclfgcllccliPfcvdslkdvehyCpnCgallgty 69 
                     p+q+dCp+C++ + T+v+++ ++ t ++a+l+cl++ ++ +++P ++ + ++veh+C+nC+++++++
     EEA20123.1 104 VPAQIDCPFCHTISLTNVTKTDSSQTTIAAVLCCLCCGIITVCLPSLLGWYQNVEHRCGNCKRKVAYK 171
                    599************************99999999988777778********************9975 PP

>> Elf1  Transcription elongation factor Elf1 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   8.9    0.0054        48      16      52 ..     102     140 ..      92     180 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.0054
        Elf1  16 kklptkFdCpfCnheksvevkldkkek..iaevsCkvCg 52 
                   +p + dCpfC+  +  +v+ + +++  ia v C  C 
  EEA20123.1 102 GDVPAQIDCPFCHTISLTNVTKTDSSQttIAAVLCCLCC 140
                 5578899******99777776666555676666666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (189 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       861  (0.0480228); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.48
# Mc/sec: 1172.01
//
Query:       EEA20124.1  [L=189]
Description: hypothetical protein PMAA_039850 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.4e-16   59.7  10.9    3.5e-16   59.2  10.9    1.3  1  zf-LITAF-like  LITAF-like zinc ribbon domain
  ------ inclusion threshold ------
        3.1    7.9   8.9         48    4.1   8.9    2.2  1  Elf1           Transcription elongation factor Elf1 like


Domain annotation for each model (and alignments):
>> zf-LITAF-like  LITAF-like zinc ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.2  10.9   3.9e-20   3.5e-16       2      69 ..     104     171 ..     103     172 .. 0.93

  Alignments for each domain:
  == domain 1  score: 59.2 bits;  conditional E-value: 3.9e-20
  zf-LITAF-like   2 eptqvdCpaCqqrvvTsveyksgkltwllalllclfgcllccliPfcvdslkdvehyCpnCgallgty 69 
                     p+q+dCp+C++ + T+v+++ ++ t ++a+l+cl++ ++ +++P ++ + ++veh+C+nC+++++++
     EEA20124.1 104 VPAQIDCPFCHTISLTNVTKTDSSQTTIAAVLCCLCCGIITVCLPSLLGWYQNVEHRCGNCKRKVAYK 171
                    599************************99999999988777778********************9975 PP

>> Elf1  Transcription elongation factor Elf1 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   8.9    0.0054        48      16      52 ..     102     140 ..      92     180 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.0054
        Elf1  16 kklptkFdCpfCnheksvevkldkkek..iaevsCkvCg 52 
                   +p + dCpfC+  +  +v+ + +++  ia v C  C 
  EEA20124.1 102 GDVPAQIDCPFCHTISLTNVTKTDSSQttIAAVLCCLCC 140
                 5578899******99777776666555676666666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (189 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       861  (0.0480228); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.29s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1269.51
//
Query:       EEA20125.1  [L=120]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00018   21.6   0.0    0.00023   21.2   0.0    1.1  1  BLUF      Sensors of blue-light using FAD
  ------ inclusion threshold ------
      0.036   13.6   0.0      0.042   13.4   0.0    1.0  1  GKAP      Guanylate-kinase-associated protein (GKAP) protein
       0.13   12.9   0.0       0.14   12.7   0.0    1.1  1  Cas_Cas6  CRISPR associated protein Cas6


Domain annotation for each model (and alignments):
>> BLUF  Sensors of blue-light using FAD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.0   3.8e-08   0.00023      23      78 ..      35      90 ..      19      94 .. 0.89

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 3.8e-08
                HHHHHHHHHHHTEEEEEEEETTEEEEEEEEEHHHHHHHHHHHHT-TTEEEEEEEEE CS
        BLUF 23 leesrenNkelgitGvLlydegvflQvLEGeeeaveelyerIkkDpRhkdvevlee 78
                 ++s ++N+++  t+ + yd++++l +L Ge+++ve++ ++I +++R +++ +  +
  EEA20125.1 35 TTQSPTHNANSTSTSTIQYDHETYLELLAGESNHVEKTANQIYEEERARELSLRAQ 90
                578999*****************************************999987666 PP

>> GKAP  Guanylate-kinase-associated protein (GKAP) protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0     7e-06     0.042     124     189 ..      19      86 ..       4      92 .. 0.72

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 7e-06
        GKAP 124 sslppPdpwlessnesssssle..esgrassacrrdgewFlkLlqaeterlegwCqqmereaeenels 189
                 +s  +P + l +++ ++++s++   +++++s+++ d e +l+Ll  e + +e+  +q+ +e++  els
  EEA20125.1  19 ASPSSPTSALTTTSPTTTQSPThnANSTSTSTIQYDHETYLELLAGESNHVEKTANQIYEEERARELS 86 
                 44445555554443333333332255667778*****************************9999997 PP

>> Cas_Cas6  CRISPR associated protein Cas6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   2.4e-05      0.14      30      93 ..      23      89 ..      12     113 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.4e-05
                TCEE.EEESS-BBEEEEEEETTCCEEEEE-TTSTTHHHHH...HHHHHHHHHHHHSS..SS---EEE CS
    Cas_Cas6 30 ssevvfktlSPivvrstkkengkkktyylspddeeFsell...kenlkkkykalygeekeeklsikp 93
                s +  + t SP + +s++++ ++++t +++ d+e + ell    + ++k  +++y+ee+ ++ls++ 
  EEA20125.1 23 SPTSALTTTSPTTTQSPTHNANSTSTSTIQYDHETYLELLageSNHVEKTANQIYEEERARELSLRA 89
                4445589********9988999999999999*********886566677799999999777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (120 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       890  (0.0496402); expected 358.6 (0.02)
Passed bias filter:                      514  (0.0286686); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.31s 00:00:00.82 Elapsed: 00:00:00.50
# Mc/sec: 715.57
//
Query:       EEA20126.1  [L=495]
Description: vacuolar targeting protein Atg24, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.6e-19   69.3   0.1    5.1e-19   68.3   0.1    1.5  1  PX            PX domain
    3.8e-14   52.8   3.7    7.8e-07   28.9   0.4    2.1  2  Vps5          Vps5 C terminal like
     0.0094   15.6   1.7       0.26   10.9   1.7    2.3  1  BAR           BAR domain
  ------ inclusion threshold ------
      0.035   14.0   0.2      0.074   12.9   0.0    1.6  2  Sec34         Sec34-like family
       0.12   13.1   1.3        2.3    9.0   0.0    2.8  3  Occludin_ELL  Occludin homology domain
       0.26   11.3   1.6        7.5    6.6   0.4    2.4  2  DUF1664       Protein of unknown function (DUF1664)


Domain annotation for each model (and alignments):
>> PX  PX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.3   0.1   1.7e-22   5.1e-19      14     112 ..      83     190 ..      71     191 .. 0.93

  Alignments for each domain:
  == domain 1  score: 68.3 bits;  conditional E-value: 1.7e-22
                 E.TTSSEEEEEEEEEETTS.....SSEEEEEEEHHHHHHHHHHHHHHHTTSTSTSSSTSGSSSSS...CTTSHHHHHHHHHHHHHHHHHHHTSCHHHHS CS
          PX  14 s.gskkhsyylyevelktg.....akewtvkRrYsdFeeLhskLlrkfprvkiPplPkkvlfgsv...rkkdeefiekrrkgLeeyLqrllnhpelrns 103
                 +  + k+ y+ y v+++t      ++ +tv+Rr++dF+ L++ L r++p++ +PplP+k+ + s+   +++ ++f+++r  +L ++++rl  hp+lr+ 
  EEA20126.1  83 EnDGTKDAYISYLVTTHTDfktfqKTDFTVRRRFRDFFFLYKTLYREYPACAVPPLPDKHKVESYvtgDRFGPDFTQRRAWSLHRFIKRLTLHPVLRRA 181
                 44567889999*****9999*******************************************99********************************** PP

                 HHHHHHHHS CS
          PX 104 evlteFLev 112
                 + l  FLe+
  EEA20126.1 182 PLLAVFLES 190
                 *******97 PP

>> Vps5  Vps5 C terminal like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.0   0.2     4e-09   1.2e-05       4     132 ..     215     341 ..     212     355 .. 0.90
   2 !   28.9   0.4   2.6e-10   7.8e-07     156     235 ..     395     474 ..     376     475 .. 0.89

  Alignments for each domain:
  == domain 1  score: 25.0 bits;  conditional E-value: 4e-09
        Vps5   4 lfkkltssisksstkfeEqDewFedkkqeldslesqLkkLykaiellvsqrkelasataelakslesLaslelskslsralsqla.eveerikellerq 101
                 +f+++ +++ ++ tk++ +D+ F++ +++ d+l++ L +++k +  + +   +l +   +la+   +L  le + +    l+ +a  v e+ + l   +
  EEA20126.1 215 IFDNFADTFVNAFTKVHKPDRRFIEVREKADKLDEDLNHVEKIVARVARREADLEADYVDLATQFRKLVPLEPEVE--MPLQVFAaSVDETSRGLKGLK 311
                 688999999999********************************************************99987655..567777526888888888999 PP

        Vps5 102 aeqdvltLgetideylrligsvksvfeqRvk 132
                  + d+ +Lg  +++   +i svks++++R +
  EEA20126.1 312 DHTDQNYLGS-LRDMEAYILSVKSLLKTREQ 341
                 9999*99997.699**************975 PP

  == domain 2  score: 28.9 bits;  conditional E-value: 2.6e-10
        Vps5 156 kaaksqqdklqqlkkeveelerkvqeaekeFeeisetikkElerFetervedfknvvekyLesaiesqkevielWetfls 235
                  +++s+++++++l+  ++el+r v++a++  e   e++ +E++ Fe+ ++ +f+ ++    e+ i   + vi+ We+f s
  EEA20126.1 395 DHEQSRRERIRKLELRIDELTREVDSAKTTSEMFDEEVVREVADFERIKAVEFRDSLGALAENHIGFYQGVINTWERFIS 474
                 4458899***********************************************************************87 PP

>> BAR  BAR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.9   1.7   8.8e-05      0.26     103     174 ..     298     370 ..     291     477 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 8.8e-05
         BAR 103 eavkklaqteeelekrvetnfldplrellekefkeiqkerkklehkrlDyDaakarlkklktkkskkakde..e 174
                 + v++ +  ++ l++ + +n l  lr +  +++  +++ +k +e+k+lD+ a  +  +k+ ++ ++ +++   +
  EEA20126.1 298 ASVDETSRGLKGLKDHTDQNYLGSLRDME-AYILSVKSLLKTREQKQLDFEALVEYRNKAVSDRDSLVTNPssA 370
                 556666777888999*************9.******************************99999888876552 PP

>> Sec34  Sec34-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   2.5e-05     0.074      11      87 ..     236     313 ..     227     340 .. 0.85
   2 ?   -3.9   0.0       3.7   1.1e+04      26      43 ..     411     428 ..     402     442 .. 0.50

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.5e-05
       Sec34  11 ecdelleqtdealeqLeeleekfksvsektsslheaceqlleeqkrleelaeeieekLkyFe.eldpitrkLnspgss 87 
                 ++ e+ e++d++ e+L+++e+ + +v+ +  +l+++  +l ++ ++l  l  e+e  L++F+ ++d+++r L+  + +
  EEA20126.1 236 RFIEVREKADKLDEDLNHVEKIVARVARREADLEADYVDLATQFRKLVPLEPEVEMPLQVFAaSVDETSRGLKGLKDH 313
                 55678899*****************************************************73689999988866665 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 3.7
       Sec34  26 Leeleekfksvsektssl 43 
                 ++el+ +++s ++ ++ +
  EEA20126.1 411 IDELTREVDSAKTTSEMF 428
                 333333333333333333 PP

>> Occludin_ELL  Occludin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.1       5.2   1.5e+04      16      30 ..     115     129 ..      96     133 .. 0.62
   2 ?    9.0   0.0   0.00078       2.3      54      97 ..     215     259 ..     194     263 .. 0.84
   3 ?    1.8   0.2      0.14   4.1e+02      29      69 ..     402     442 ..     396     450 .. 0.68

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 5.2
  Occludin_ELL  16 eFnkeYkeYkelhae 30 
                    F++ +  Yk+l++e
    EEA20126.1 115 RFRDFFFLYKTLYRE 129
                   455555555555554 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00078
  Occludin_ELL  54 eykkieeeilqeykklkk.dpeyqekkkrceyLkekLshiKklik 97 
                    +++ ++  ++ + k++k d+++ e +++ ++L e L+h+ k ++
    EEA20126.1 215 IFDNFADTFVNAFTKVHKpDRRFIEVREKADKLDEDLNHVEKIVA 259
                   66788899999*****999********************988775 PP

  == domain 3  score: 1.8 bits;  conditional E-value: 0.14
  Occludin_ELL  29 aeleevskkfseLerelkelkegsk.eykkieeeilqeykkl 69 
                   +++++++ ++ eL re++++k++s+   +++++e + +++++
    EEA20126.1 402 ERIRKLELRIDELTREVDSAKTTSEmFDEEVVRE-VADFERI 442
                   5677777788888888888888888444455555.5556555 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0      0.03        89      88     120 ..     236     268 ..     220     272 .. 0.79
   2 ?    6.6   0.4    0.0025       7.5      61     100 ..     404     443 ..     384     448 .. 0.86

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.03
     DUF1664  88 evtevredlseigedvesvkeavegleskleri 120
                    evre+ ++++ed+++v+++v  ++ + +++
  EEA20126.1 236 RFIEVREKADKLDEDLNHVEKIVARVARREADL 268
                 567899999999999999999998877665555 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0025
     DUF1664  61 krhLssridrvdkkldeqkeiskeikeevtevredlseig 100
                  r+L+ rid++ +++d+ k +s+  +eev +   d ++i+
  EEA20126.1 404 IRKLELRIDELTREVDSAKTTSEMFDEEVVREVADFERIK 443
                 58999************************98888887776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (495 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       760  (0.0423894); expected 358.6 (0.02)
Passed bias filter:                      547  (0.0305092); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.46
# Mc/sec: 3226.90
//
Query:       EEA20127.1  [L=80]
Description: hypothetical protein PMAA_039880 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (80 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       278  (0.0155056); expected 358.6 (0.02)
Passed bias filter:                      242  (0.0134977); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.34u 0.25s 00:00:00.59 Elapsed: 00:00:00.39
# Mc/sec: 621.66
//
Query:       EEA20128.1  [L=813]
Description: pheromone processing endoprotease KexB [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.7e-37  129.3   0.6    2.5e-37  128.8   0.6    1.2  1  Peptidase_S8  Subtilase family
    9.5e-25   86.5   0.7    1.8e-24   85.6   0.7    1.5  1  P_proprotein  Proprotein convertase P-domain


Domain annotation for each model (and alignments):
>> Peptidase_S8  Subtilase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  128.8   0.6   2.7e-41   2.5e-37       1     298 []     183     461 ..     183     461 .. 0.81

  Alignments for each domain:
  == domain 1  score: 128.8 bits;  conditional E-value: 2.7e-41
                   -TT-EEEEECS-B-TT-TTTGGGEEE..EEEE---TTSG.GGEETT-SS-TT-SC-SSS....HHHHHHHHHH-B..SSSSSB-SSTTSEEEEEE-S CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8   1 gkgvlvavlDtGvdpshpdlsvttdgerklvdvideegagfngadsettstnwarddngnsieHGthvAGiaaanapeegekngvapgakilsvkvl 97 
                   g gv+ a++D+G+d    dl++++  e + +         fn+ ds++  +   +d+      HGt++AG +aa  +++ + +g+a++ k++++++l
    EEA20128.1 183 GAGVVTAIVDDGLDMYSNDLKANYFAEGSWD---------FNE-DSPEPRPLLRDDK------HGTRCAGEVAAV-RNNVCGVGLAYDSKVAGIRIL 262
                   6899***********9999997766655543.........433.3333333333333......************.********************* PP

                   STTSB-HH..HHHHHHHHHHHHCT-SEEEE-EESCETTCHHCHHHHHH.......HHHHHH.CCT-EEEEE--SS-T-HHEEE-TTCEECTTTSTTC CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8  98 dtsggsmetgteliraieeaaedkvdvinmslgestslpktgrsieal.......ainravnkkgvlvviSaGNngktgsslqagspvgtpstsknv 187
                   +++       ++ ++ai++ ++ k d++++s+g + ++++t + +  l        i +++  kg+++v++aGN g +g+  +++ +++t+s +   
    EEA20128.1 263 SKPIDD----ADEAAAINYGFQ-KNDIYSCSWG-PRDDGETMEAPGILvrramvnGIVQGRGGKGSIYVFAAGNGGFYGD--NCNFDGYTNSIYS-- 349
                   999976....577899999999.9*********.*********999889999777666666688****************..**********999.. PP

                   EEEEEESTTSSB-TT--B-TT.......-EEEE-S-CCCCCCCCCHHHTTTHHEEEE-SHHHCHHHHHHHHHHHHHHHTT--HHHHHHHHHCCS-EE CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8 188 itvgayttegkiapfSsrGpssdgklkpdivapGgnivstwsrqsnnsaglssyqsmsGTSmAsPnaagaaAlllsalpkltpetvraallntAqdl 284
                   +tvga++ +g+  ++S+ ++++       +va+ + ++ ++ + +  + +++ +  + GTS+A P+++ga+Al ls  p+lt+++v+ +l+ t  ++
    EEA20128.1 350 VTVGAIDRQGQHPSYSEACSAQL------VVAYSSGGSDSIHTTDVGT-DSC-TSIHGGTSAAGPLVSGAIALALSVRPELTWRDVQYLLIETSVPI 438
                   *********************96......5555555333443333222.222.789**************************************999 PP

                   ..................SSSSSSTT CS
                   ............xxxxxxxxxxxxxx RF
  Peptidase_S8 285 ............gkadniesfaqGaG 298
                               gk     s+++G+G
    EEA20128.1 439 htdgdevqmtpiGK---EFSHQFGYG 461
                   88877774433222...244556665 PP

>> P_proprotein  Proprotein convertase P-domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.6   0.7     2e-28   1.8e-24       1      86 []     521     607 ..     521     607 .. 0.97

  Alignments for each domain:
  == domain 1  score: 85.6 bits;  conditional E-value: 2e-28
                   EEEEEEEEEEEESSGGGEEEEEE-TTS-EEEEE---TT---SS-EEEEEEEESTTTTS---EEEEEEEEE.SSTT--EEEEEEEEEE CS
  P_proprotein   1 lehvqvsvnithtrrgdlritLvsPsGtrsvLlnrrgkdksrsgfldwtfmsthlwgeraeGeWkLevkd.seeedtgtlkswkLrl 86 
                   +ehv+v++ni+htrrgdl+ +L  P+G +s+L  +r+kd + +g++dwtfms+++wge+ eG W + vkd   +e+tg +++w+++l
    EEA20128.1 521 IEHVTVTMNINHTRRGDLSTELRGPQGIVSHLSVPRNKDGAIAGYEDWTFMSVAHWGETGEGVWSVVVKDtVVNENTGVFTDWRMTL 607
                   69********************************************************************88899********9975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (813 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       600  (0.0334653); expected 358.6 (0.02)
Passed bias filter:                      508  (0.028334); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.74u 0.26s 00:00:01.00 Elapsed: 00:00:00.46
# Mc/sec: 5338.63
//
Query:       EEA20129.1  [L=1445]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    0.00029   20.0   0.0     0.0021   17.2   0.0    2.1  1  PhoD        PhoD-like phosphatase
  ------ inclusion threshold ------
      0.028   14.3   0.2      0.061   13.2   0.2    1.5  1  CAMSAP_CC1  Spectrin-binding region of Ca2+-Calmodulin


Domain annotation for each model (and alignments):
>> PhoD  PhoD-like phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   2.3e-07    0.0021      16     284 ..     776    1087 ..     753    1109 .. 0.56

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 2.3e-07
        PhoD   16 ayrelaee...edlDlvlhlGDyiYeyg..pgeyaseaaelgrevepp...........keivtladYReryaqyktdadlqaahaaapfivvwDDH 96  
                   +r++ +e     + ++l  GD +Y ++  +++ + e    + + ++p            +++  + Y + ya   +   ++ a+ ++p++ +wDDH
  EEA20129.1  776 LWRDVLNEhqtRPFHVMLGGGDQLYCDKvmQDSEQFE---EWTRIKNPhhknnaplspaFKAELESFYLNHYAACFSRGLFSLANCQIPMVNIWDDH 869 
                  566666654323678888889******8443333333...2222222223457889885444444557788899999999999************** PP

        PhoD   97 EvaNnswsggaenhqeetegdfekrkaaAlqAyfEw..mPireak...pgee............eriyrs..feyGdladlflLDtRqyrrdqavsy 174 
                   + +  + +    h   +   f+ + + A++ y+ +  + + e++   +               ++  rs  +++G+ ++++ +D R+ r +++v  
  EEA20129.1  870 DIIDG-FGS-YPDHL-MRSPVFSGLGNVAFKYYMLFqhQSLPEETeadE--PswllgadvgpyiKERSRSlfMSLGKGVSFLGIDCRTERMREEVVS 961 
                  ***99.544.34444.467777888888888775442233322212230..1333333333344222444114567778888888888888888755 PP

        PhoD  175 e.......gd.eleaaeaevkdpartlLGe....eQeqwLkaeLkasrar.WkvlaqqvlmskvdldaelaegalpvnlDawdGypaeRe.....rl 253 
                  e       ++  +e ++ +v ++   lLG     + + wL++ L++      k l+   l+s +  + +   + l    D w     + e     + 
  EEA20129.1  962 EhtydliwDRcYREIERGQV-KHLIVLLGVpiayPRLVWLENILSSRAMDpVKALTRAGLFSGFVNKFDGGVEILDDVDDHWTAKHHKTErtlliED 1057
                  54555444222222222222.3345667752222466777777765555567777777777777733222222244455666554443333333322 PP

        PhoD  254 letikeakirnvVvLtGDvHaawandldykd 284 
                  l+ ++++k  ++ +L+GDvH a+++++ y +
  EEA20129.1 1058 LQDLAAEKSVRITILGGDVHLAAIGQF-YSN 1087
                  223333344555567788887777777.544 PP

>> CAMSAP_CC1  Spectrin-binding region of Ca2+-Calmodulin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.2   6.8e-06     0.061      20      47 ..     216     244 ..     194     259 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 6.8e-06
  CAMSAP_CC1  20 rlkLEEKR.RaIEaqKrkiEaalarqRqk 47 
                 ++  EEKR R IEa+Kr  E + +r  q+
  EEA20129.1 216 GMSKEEKRaRVIEAEKRLREKMANRESQR 244
                 4555****888**************9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1445 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       676  (0.0377043); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.93u 0.35s 00:00:01.28 Elapsed: 00:00:00.53
# Mc/sec: 8174.03
//
Query:       EEA20130.1  [L=373]
Description: thioredoxin reductase Trr1/Trr2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.3e-51  173.9   0.1    5.3e-51  173.6   0.1    1.1  1  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    1.5e-18   67.1   0.1    6.6e-17   61.7   0.0    2.1  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
    3.5e-16   59.5   0.3    1.1e-13   51.5   0.1    2.7  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
    0.00012   21.5   0.4    0.00028   20.2   0.1    1.8  2  Thi4           Thi4 family
    0.00013   22.4   0.2       0.01   16.2   0.1    2.7  2  NAD_binding_7  Putative NAD(P)-binding
    0.00031   20.9   0.3       0.14   12.4   0.1    2.6  2  NAD_binding_8  NAD(P)-binding Rossmann-like domain
    0.00064   19.1   2.7        2.1    7.5   0.0    3.1  3  FAD_binding_3  FAD binding domain
     0.0019   17.4   0.0       0.21   10.7   0.0    2.9  3  K_oxygenase    L-lysine 6-monooxygenase (NADPH-requiring)
     0.0035   16.7   0.4       0.18   11.1   0.1    2.2  2  FAD_oxidored   FAD dependent oxidoreductase
  ------ inclusion threshold ------
      0.012   14.7   3.8        2.1    7.3   0.1    4.0  5  GIDA           Glucose inhibited division protein A
      0.023   14.3   4.3        3.6    7.1   0.0    3.6  4  DAO            FAD dependent oxidoreductase
       0.12   12.4   0.4         19    5.3   0.0    2.9  3  Shikimate_DH   Shikimate / quinate 5-dehydrogenase
        1.4    7.9   6.5       0.88    8.6   0.8    2.8  4  FAD_binding_2  FAD binding domain


Domain annotation for each model (and alignments):
>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  173.6   0.1   3.8e-54   5.3e-51       2     292 ..       5     308 ..       4     310 .. 0.92

  Alignments for each domain:
  == domain 1  score: 173.6 bits;  conditional E-value: 3.8e-54
                  SEEEE--SHHHHHHHHHHHHHTS-EEEEE...TTHCHHHCSHHHHCHHHHHHHHHHHHH.........HHHHCHHHHCCCCHCCTCEEEEESCEEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxx.........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2   2 dvvviGgGpAGlaaaltlaqagakvtlve...legtclnggcllskallgvaedaeias.........evvkklnqgielllgeevvkidpgkkkvkl 87 
                  +vv+iG+GpA+++aa++l++a+++ +++e   ++gt  +g+   ++ ++++++++  +           + k+++++i+  ++ +++++d+ k+ + l
   EEA20130.1   5 KVVIIGSGPAAHTAAIYLSRAELQPVMYEgmlAGGTAAGGQLTTTTDIENFPGFPTGIGgselmdnmrSQSKRFGTEII--TE-TITRVDFSKRPFRL 99 
                  8*******************************************************999**999887766666666654..33.67************ PP

                  TEEEC...TCEEEEEESEEEE---EEE-BCTCTTC.TTBEECCSECHHHHHHCCSS-TSEEEEES-SHHHHHHHHHHHHHT-EEEEEESSSSSSTTS- CS
                  xxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  88 ekkke...gdeekiaydklvlAtGssprdlgipGvaenvgklvrtldsaealklkllpkrivvvGgGyiGvElAaalaklgkevtlveardrllrald 182
                   k+ +   ++e   ++d++++AtG+++r+l++pG++++++ ++++++ +++     ++k + v+GgG  + E A++l+k+g++vt++ + d+l     
   EEA20130.1 100 WKEWSdgpDEEPAHTADAIIIATGANARRLDLPGEKQYWQNGISACAVCDGAVPIFRNKPLFVIGGGDSAAEEAMFLTKYGSHVTVLVRKDKLR---- 193
                  9887799888889999*****************************************************************************7.... PP

                  HHHHHHHHHHHHHT.TEEEEESCEEEEEEETTE........EEE.EEETTSCEEEESEEEE-S-EEES-HHCSHCCT-EEEETTEEE--TTS.BESST CS
                  xxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxx........xxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxx RF
  Pyr_redox_2 183 kelsaaleealeke.Gvevklgtsvkeidgnge........kle.vvledgeeidadlvvvavGvrpstelleeklglelderggivvdefl.rtnvp 269
                    +s+a++++l ++ +v+v+++++++++ g++         k++ vv++++e++da  +++avG  p t+l   k ++eld+ g+iv+ +    t+vp
   EEA20130.1 194 --ASKAMAKRLLANpKVTVRFNSVATQVLGEEGprglmthiKVKnVVTGEEETLDANGLFYAVGHDPATTL--VKGQVELDSEGYIVTQPGTsYTSVP 287
                  ..7888888888877***********************9887779************************99..59**************9984589** PP

                  TEEE-GGGCTECCSS--HHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 270 giyaiGDvaggkggpelaqaAvq 292
                  g++a+GDv+  ++++++a ++  
   EEA20130.1 288 GVFAAGDVQ--DKRYRQAITSAG 308
                  *********..777777776655 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.1     0.029        41       1      23 [.       7      29 ..       5      38 .. 0.87
   2 !   61.7   0.0   4.8e-20   6.6e-17     123     305 .]     113     293 ..      83     293 .. 0.81

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.029
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagled 23
                 +IiG GPa  +aai l +a+l+ 
   EEA20130.1  7 VIIGSGPAAHTAAIYLSRAELQP 29
                 79******999999999999964 PP

  == domain 2  score: 61.7 bits;  conditional E-value: 4.8e-20
  Pyr_redox_3 123 yeAkkviiAtGefdkPnklnipGeek...lvkhyskvk..efhkyagqkvvViGgknSavDaAlelvrkgaeVtvvtrgseiekeesdpsysl.kpdi 214
                   +A+ +iiAtG   + ++l+ pGe++   + +    v   ++  ++++ + ViGg++Sa++ A+ l ++g++Vtv++r+++++++++  +  l +p +
   EEA20130.1 113 HTADAIIIATGA--NARRLDLPGEKQywqNGISACAVCdgAVPIFRNKPLFVIGGGDSAAEEAMFLTKYGSHVTVLVRKDKLRASKAMAKRLLaNPKV 208
                  5799*******9..9**********744345555555322455678999***********************************99877775548*** PP

  Pyr_redox_3 215 enrleelvke..ekikvlfnaevkeikekeeeykvktedgkkvevkddvvlatGykpdlsflkkslfeldedgrpvlteeteetnvpglflaG 305
                    r++++ ++  +  +   +  ++ ik k    +v t ++++    +  ++a+G +p ++++k  ++eld++g++v ++ t  t vpg+f aG
   EEA20130.1 209 TVRFNSVATQvlG--EEGPRGLMTHIKVK----NVVTGEEET-LDANGLFYAVGHDPATTLVK-GQVELDSEGYIVTQPGTSYTSVPGVFAAG 293
                  *****98875321..22223334444443....444555344.556999***********999.9**************************99 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   0.0     0.023        31       1      22 [.       5      26 ..       5      33 .. 0.88
   2 !   51.5   0.1     8e-17   1.1e-13       3      79 ..     161     235 ..     159     242 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.023
                EEEEECSSHHHHHHHHHHHHTT CS
   Pyr_redox  1 kvvvvGgGyiglElAgalaelg 22
                kvv++G+G  +  +A +l++  
  EEA20130.1  5 KVVIIGSGPAAHTAAIYLSRAE 26
                79****************9865 PP

  == domain 2  score: 51.5 bits;  conditional E-value: 8e-17
                 EEECSSHHHHHHHHHHHHTTSEEEEEESSSSSSTTSSHHHHHHHHHHHHHT.TEEEECSEEEEEEEEETT..S.EEEEEEE CS
   Pyr_redox   3 vvvGgGyiglElAgalaelgkkVtvversdkllrllDeeaskilqeklekn.gievllntkveeiegsed..g.vesvklk 79 
                  v+GgG+++ E+A +l+++g++Vtv++r+dkl+      ask+++++l +n +++v++n++++++ g+e   g ++++k+k
  EEA20130.1 161 FVIGGGDSAAEEAMFLTKYGSHVTVLVRKDKLR------ASKAMAKRLLANpKVTVRFNSVATQVLGEEGprGlMTHIKVK 235
                 7********************************......*********9999*************9766433666666665 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.1     2e-07   0.00028      16      64 ..       2      47 ..       1      54 [. 0.90
   2 ?   -2.3   0.0       1.5   2.1e+03      93      94 ..     187     188 ..     158     248 .. 0.61

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 2e-07
                TEEEEEEE--SHHHHHHHHHHHHCTTS-EEEEESSSS--TTTTTTSTTB CS
        Thi4 16 aesDvvivGaGssGLtaayylakkpdlkvailersvspGGGawlGGqlf 64
                + s vvi+G+G++  taa yl+++ +l+ ++ e  ++  GG+  GGql 
  EEA20130.1  2 VHSKVVIIGSGPAAHTAAIYLSRA-ELQPVMYEGMLA--GGTAAGGQLT 47
                6789********************.*********997..8899999985 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1.5
                 ES CS
        Thi4  93 vk 94 
                 v+
  EEA20130.1 187 VR 188
                 22 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.0     0.066        91       8      32 ..       4      28 ..       1     128 [. 0.81
   2 !   16.2   0.1   7.5e-06      0.01       5      40 ..     155     190 ..     154     256 .. 0.83

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.066
  NAD_binding_7  8 kkvlvvGgGevAarkvrklleagak 32
                    kv+++G G+ A + +  l +a+ +
     EEA20130.1  4 SKVVIIGSGPAAHTAAIYLSRAELQ 28
                   689*********9988888887655 PP

  == domain 2  score: 16.2 bits;  conditional E-value: 7.5e-06
  NAD_binding_7   5 lkgkkvlvvGgGevAarkvrklleagakvtvvapev 40 
                    +++k   v+GgG+ Aa+ +  l ++g +vtv+  + 
     EEA20130.1 155 FRNKPLFVIGGGDSAAEEAMFLTKYGSHVTVLVRKD 190
                    689999*************************87774 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.4   0.1    0.0001      0.14       1      40 [.       8      51 ..       8      76 .. 0.76
   2 !    6.1   0.0    0.0091        13       1      26 [.     162     187 ..     162     198 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.0001
                   EE--SHHHHHHHHHHHCCTEEEEEE-S....SSSSSGGG-EECE CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllek....rdrlGGraasyev 40
                   I+G+G ++ +aA +L++a ++ + +e     ++  GG++++ ++
     EEA20130.1  8 IIGSGPAAHTAAIYLSRAELQPVMYEGmlagGTAAGGQLTTTTD 51
                   9******************9999999544435667777777655 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.0091
                    EE--SHHHHHHHHHHHCCTEEEEEE- CS
  NAD_binding_8   1 IvGaGlsGlvaAylLakagfdvllle 26 
                    ++G+G s++  A +L+k+g +v++l 
     EEA20130.1 162 VIGGGDSAAEEAMFLTKYGSHVTVLV 187
                    8**********************985 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.5   0.0    0.0015       2.1       3      23 ..       5      25 ..       3      35 .. 0.87
   2 ?    4.3   0.0     0.014        19       5      35 ..     161     191 ..     158     202 .. 0.83
   3 !    6.1   0.4     0.004       5.5     140     268 ..     232     358 ..     193     370 .. 0.70

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0015
                   EEEEE--SHHHHHHHHHHHHT CS
  FAD_binding_3  3 dVlIVGaGpaGlmlallLsea 23
                   +V+I+G+Gpa  ++a  Ls+a
     EEA20130.1  5 KVVIIGSGPAAHTAAIYLSRA 25
                   8*****************998 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.014
                    EEE--SHHHHHHHHHHHHTTHHEEEEESSSS CS
  FAD_binding_3   5 lIVGaGpaGlmlallLseaGvrvvlvekrst 35 
                     ++G+G + +  a++L+++G  v+++ + ++
     EEA20130.1 161 FVIGGGDSAAEEAMFLTKYGSHVTVLVRKDK 191
                    59********************999877543 PP

  == domain 3  score: 6.1 bits;  conditional E-value: 0.004
                    CEEEECCTTEEEEEEEE...EEEE--GTT-HHHHHHTGGEEE...EEEEEEEEEEEEEEEC.-SCCCTTCCEEEEECCTTEEEEEECCETEEEEEE CS
  FAD_binding_3 140 aevrdketgeeetvrak...YlvGaDGgrStvrktlgiefeg...eetvyeagvldvlfda.dlsdiveplvlilsaesrgvmviPlentlerfyv 228
                     +v++  tgeeet++a+   Y vG D + + v  ++ ++ eg   ++  +  +++  +f+a d++d +    +i+sa s+ ++ +  e+       
     EEA20130.1 232 IKVKNVVTGEEETLDANglfYAVGHDPATTLVKGQVELDSEGyivTQPGTSYTSVPGVFAAgDVQDKRYR-QAITSAGSGCIAALEAEK------- 319
                    3566889*********8888***************99997763336667778888889999999977776.899999999877666666....... PP

                    EEECCE-GGGSCCCHHHHHHHHHHHHHHTTSSCEEEEEEE CS
  FAD_binding_3 229 qvearaekeersekfteeevkarlreivgektldveieev 268
                     + a++e++e+++++++e+   r++ +v+e++++   +++
     EEA20130.1 320 -FLAEEEAGEEEPAVKTEVGQSRIEPAVAEQDAQSAQQKK 358
                    .445666666777777777777777777777666655544 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0      0.51   7.1e+02       5      21 ..       6      22 ..       3      32 .. 0.53
   2 !   10.7   0.0   0.00015      0.21     119     230 ..      87     194 ..      68     200 .. 0.64
   3 ?    2.4   0.0      0.05        68     112     161 ..     209     259 ..     199     266 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.51
  K_oxygenase  5 ligiGiGpsnLsLaill 21
                 +++iG Gp++ + ai l
   EEA20130.1  6 VVIIGSGPAAHTAAIYL 22
                 34455555444444444 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 0.00015
  K_oxygenase 119 veevepdeeeeeelltveskdaegeeeelearnlvlgvGtepk...iPevleklegkervvHsseylerkeellakkriaVvGsGqSaaeifedllrr 213
                  +++v+++++   ++l  e +d  +ee  ++a ++++++G ++    +P   +  +   + + +  +        ++k + V+G+G Saae ++ l++ 
   EEA20130.1  87 ITRVDFSKRP--FRLWKEWSDGPDEEPAHTADAIIIATGANARrldLPGEKQYWQ---NGISACAVCDGAVPIFRNKPLFVIGGGDSAAEEAMFLTKY 179
                  4444444433..3344444455566778888889999986664122454444443...34444444444445788999************99999887 PP

  K_oxygenase 214 qkkvelklvtrsealep 230
                   +  ++++++r+++l++
   EEA20130.1 180 GS--HVTVLVRKDKLRA 194
                  76..6777777777765 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.05
  K_oxygenase 112 qvrfgeeveevepdeeeeeelltveskd.aegeeeelearnlvlgvGtepk 161
                  +vrf++  ++v  +e  +  + ++++k+  +geee+l a+ l  +vG  p+
   EEA20130.1 209 TVRFNSVATQVLGEEGPRGLMTHIKVKNvVTGEEETLDANGLFYAVGHDPA 259
                  488999999999988876666677777779999999999999999999885 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.1   0.1   0.00013      0.18       2      68 ..       6      72 ..       5      98 .. 0.71
   2 ?    4.2   0.0     0.016        22      87     136 ..     193     247 ..     176     354 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00013
  FAD_oxidored  2 vvVvGGgpaGvaAAiaAaraGakvlLveergvlGGlltsglvatdignkaeeqvvtgi.areflerlr 68
                  vv++G+gpa  +AAi   ra  + ++ e     GG++++g ++t +  ++     tgi   e+++++r
    EEA20130.1  6 VVIIGSGPAAHTAAIYLSRAELQPVMYE-GMLAGGTAAGGQLTTTTDIENFPGFPTGIgGSELMDNMR 72
                  9**********************99986.667888888877755444332222333331245555554 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.016
  FAD_oxidored  87 evakavleemlaeagvtvllntrlveveke.gkr..iesvtveske.g.rktirA 136
                   ++ ka+++ +la+++vtv +n+++++v  e g+r  +++++v++   g ++t+ A
    EEA20130.1 193 RASKAMAKRLLANPKVTVRFNSVATQVLGEeGPRglMTHIKVKNVVtGeEETLDA 247
                   56788999999****************9974666789999998877666777766 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   0.1    0.0015       2.1       1      29 [.       5      40 ..       5      88 .. 0.77
   2 ?   -2.4   0.0       1.4   1.9e+03     140     153 ..     114     127 ..     109     141 .. 0.73
   3 ?    2.1   0.1      0.06        83       3      29 ..     161     187 ..     159     194 .. 0.86
   4 ?    2.9   0.0     0.033        45      82     147 ..     180     253 ..     167     269 .. 0.77
   5 ?    1.7   0.0     0.076   1.1e+02     353     391 ..     284     324 ..     275     325 .. 0.78

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0015
                CEEEE-SSHHHHHHHHHHHHTT--EEEE.......E CS
        GIDA  1 dviViGgGhAGceAAlaaarlGakvlLi.......t 29
                +v++iG G A   AA+ ++r+ ++ +++       t
  EEA20130.1  5 KVVIIGSGPAAHTAAIYLSRAELQPVMYegmlaggT 40
                69*********************9999977666663 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 1.4
                 EECEEEE--TT-BT CS
        GIDA 140 kakavviatGtflk 153
                 +a+a++iatG+  +
  EEA20130.1 114 TADAIIIATGANAR 127
                 5789******9444 PP

  == domain 3  score: 2.1 bits;  conditional E-value: 0.06
                 EEE-SSHHHHHHHHHHHHTT--EEEEE CS
        GIDA   3 iViGgGhAGceAAlaaarlGakvlLit 29 
                  ViGgG +  e A+ + + G +v+ ++
  EEA20130.1 161 FVIGGGDSAAEEAMFLTKYGSHVTVLV 187
                 7*********************98774 PP

  == domain 4  score: 2.9 bits;  conditional E-value: 0.033
                 -CCC-EEEEEE-HHHHHHHHHHHHHTSTTEEEEES-EEEEEECT.........TEEEEEEETTS-EEEECEEEE- CS
        GIDA  82 Gpavralraqvdrelyskevteklenepnleiieeeveelivee.........kkvkgvvtedgetikakavvia 147
                 G  v  l +  d+ + sk++ ++l ++p+++++ ++v+  ++ e          kvk vvt ++et+ a+    a
  EEA20130.1 180 GSHVTVL-VRKDKLRASKAMAKRLLANPKVTVRFNSVATQVLGEegprglmthIKVKNVVTGEEETLDANGLFYA 253
                 5556666.67799999****************9888865444444888888777888888888888877755555 PP

  == domain 5  score: 1.7 bits;  conditional E-value: 0.076
                 SSSBTEEE-CGGGTB-SHHHH...HHHHHHHHHHHHHHHCTS CS
        GIDA 353 kkvkgLflAGqinGteGYeEa...aaqGllAGinaarkakgk 391
                  +v+g+f+AG++     Y  a   a++G++A++ a + ++++
  EEA20130.1 284 TSVPGVFAAGDVQDKR-YRQAitsAGSGCIAALEAEKFLAEE 324
                 56999*******9998.7665221679******999877665 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.5     0.027        37       1      25 [.       5      31 ..       5      49 .. 0.79
   2 ?    7.1   0.0    0.0026       3.6     147     207 ..      66     129 ..      57     145 .. 0.70
   3 ?    0.1   0.0      0.36   4.9e+02       4      32 ..     162     192 ..     160     205 .. 0.82
   4 ?    1.9   0.1     0.095   1.3e+02     148     207 ..     194     263 ..     190     337 .. 0.63

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.027
                EEEEECTSHHHHHHHHHHHHTT..EEE CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..Vtl 25
                +vviiG+G +  ++A +L+r+    + 
  EEA20130.1  5 KVVIIGSGPAAHTAAIYLSRAElqPVM 31
                59****************997555444 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0026
                 HHHHHHHHHHHHTT-EEEESECEEEE..EEEETCEEEEE....EECTEEE.EEEEEEEE--GGGHHHH CS
         DAO 147 kltaalaraaealGveilegtevtgl..eeedgkvwgve....rttpgen.daadavVnaaGawsdll 207
                 +l+  ++++ ++ G ei+++ ++t++  +++  ++w+      +   +e  ++ada+++a+Ga ++ l
  EEA20130.1  66 ELMDNMRSQSKRFGTEIITE-TITRVdfSKRPFRLWKEWsdgpD---EEPaHTADAIIIATGANARRL 129
                 67888888889999999999.88888222222344544454443...4444568**********8754 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.36
                 EECTSHHHHHHHHHHHHTT..EEEEESSSST CS
         DAO   4 iiGGGiiGlstAyeLarrg..Vtllekgdia 32 
                 +iGGG   +  A++L++ g  Vt+l ++d +
  EEA20130.1 162 VIGGGDSAAEEAMFLTKYGshVTVLVRKDKL 192
                 99999999999*****9999*9999887655 PP

  == domain 4  score: 1.9 bits;  conditional E-value: 0.095
                 HHHHHHHHHHHTT.-EEEESECEEEE..EEEE.......TCEEEEEEECTEEEEEEEE..EEE--GGGHH..HH CS
         DAO 148 ltaalaraaealG.veilegtevtgl..eeed.......gkvwgverttpgendaada..vVnaaGawsd..ll 207
                 + +a+a+++ a+  v++++++ +t +  ee +       +kv++v  +t ge+++ da  +  a G+     l+
  EEA20130.1 194 ASKAMAKRLLANPkVTVRFNSVATQVlgEE-GprglmthIKVKNV--VT-GEEETLDAngLFYAVGHDPAttLV 263
                 56899999666644******8888864333.24455555566666..55.333334445588888876443233 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.013        19      12      39 ..       3      30 ..       1      32 [. 0.88
   2 ?   -0.5   0.0      0.83   1.1e+03      73      89 ..     112     128 ..     109     153 .. 0.79
   3 ?    3.4   0.0     0.054        75      11      69 ..     156     215 ..     149     221 .. 0.74

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.013
                  T-EEEEES-SHHHHHHHHHHHCCT-CEE CS
  Shikimate_DH 12 ekkvlliGaGemaelvakhLlakgvkkv 39
                  ++kv++iG G  a+ +a +L++++++ v
    EEA20130.1  3 HSKVVIIGSGPAAHTAAIYLSRAELQPV 30
                  579*****************99988766 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.83
                   HHT-SEEEE-SSSSS-S CS
  Shikimate_DH  73 laeadvvisataseepi 89 
                    + ad +i+at+++   
    EEA20130.1 112 AHTADAIIIATGANARR 128
                   5789*******998765 PP

  == domain 3  score: 3.4 bits;  conditional E-value: 0.054
                   TT-EEEEES-SHHHHHHHHHHHCCT-CEEEEEESS..HHHHHHHHHHHT.ET-EEEEGCGH CS
  Shikimate_DH  11 kekkvlliGaGemaelvakhLlakgvkkvvvaNRt..lerakelaeelkgeeiealkleel 69 
                   ++k   +iG G  a + a  L + g + v+v+ R   l+  k++a++l ++   +++++++
    EEA20130.1 156 RNKPLFVIGGGDSAAEEAMFLTKYGSH-VTVLVRKdkLRASKAMAKRLLANPKVTVRFNSV 215
                   567789************999988877.888888621345577888887766666666655 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.8   0.00064      0.88       2      31 ..       6      35 ..       5      48 .. 0.82
   2 ?   -2.0   0.0         1   1.4e+03       4      41 ..     162     199 ..     160     207 .. 0.83
   3 ?   -0.9   0.1      0.47   6.5e+02     146     200 ..     197     255 ..     181     281 .. 0.75
   4 ?    0.4   0.1      0.19   2.6e+02     386     406 ..     280     300 ..     239     311 .. 0.66

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00064
                   EEEE--SHHHHHHHHHHHHTTT-EEEEESS CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGlkvavveke 31
                   v++iGsG A  +AA+ +++a l+ ++ e +
     EEA20130.1  6 VVIIGSGPAAHTAAIYLSRAELQPVMYEGM 35
                   9******************99987766655 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1
                    EE--SHHHHHHHHHHHHTTT-EEEEESSSGGGSGGGG- CS
  FAD_binding_2   4 ViGsGlAGLaAAleaaeaGlkvavvekeqefggataws 41 
                    ViG+G +    A+ +++ G  v+v+  +++ + + a++
     EEA20130.1 162 VIGGGDSAAEEAMFLTKYGSHVTVLVRKDKLRASKAMA 199
                    99999999999999999999999888887777666655 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 0.47
                    HHHHHHHTCT.EEEEESEEEEEEEECTT...EEEEEEEEETTTTCEEEEEESEEEE--- CS
  FAD_binding_2 146 rlvesarkag.vdfqerteadeLivedg...rvtGavvenpesgrevrirakavvlatg 200
                    ++++++++++ v+++++  a++++ e+g    +t + v+n  +g+e+++ a+++  a g
     EEA20130.1 197 AMAKRLLANPkVTVRFNSVATQVLGEEGprgLMTHIKVKNVVTGEEETLDANGLFYAVG 255
                    45566666656999999999999999887777777777777888888888877666555 PP

  == domain 4  score: 0.4 bits;  conditional E-value: 0.19
                    TTEEESSBTEEE-STCEESSS CS
  FAD_binding_2 386 dadgqpipGLYAaGevaaggv 406
                    + + + +pG +AaG v    +
     EEA20130.1 280 GTSYTSVPGVFAAGDVQDKRY 300
                    4455789*******9975555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (373 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       546  (0.0304535); expected 358.6 (0.02)
Passed bias filter:                      413  (0.0230353); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.58u 0.32s 00:00:00.89 Elapsed: 00:00:00.46
# Mc/sec: 2447.01
//
Query:       EEA20131.1  [L=465]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.2e-74  249.7  10.2    2.1e-73  247.9  10.2    1.7  1  Dynamitin      Dynamitin
     0.0059   16.6   0.8     0.0059   16.6   0.8    3.4  4  Laminin_II     Laminin Domain II
  ------ inclusion threshold ------
      0.022   15.0   0.2        4.7    7.6   0.0    2.7  2  DUF948         Bacterial protein of unknown function (DUF948)
      0.045   14.0   5.9        4.7    7.5   0.2    3.6  3  Spc24          Spc24 subunit of Ndc80
      0.078   11.6   2.4       0.07   11.7   0.4    1.9  2  FapA           Flagellar Assembly Protein A
      0.098   12.4  18.7      0.073   12.8   1.6    4.4  5  DivIC          Septum formation initiator
       0.19   11.9  10.2          1    9.6   2.4    3.2  3  Jnk-SapK_ap_N  JNK_SAPK-associated protein-1
       0.33   11.6  10.0        3.2    8.4   1.1    4.1  3  SlyX           SlyX
       0.55   10.4   8.5      0.056   13.6   1.5    2.7  3  End3           Actin cytoskeleton-regulatory complex protein 
        1.3    8.9   7.3       0.35   10.8   1.4    2.7  3  MIP-T3_C       Microtubule-binding protein MIP-T3 C-terminal 
        1.7    8.6  10.1        2.9    8.0   0.1    4.2  4  FlxA           FlxA-like protein
          2    9.0  13.7        2.5    8.6   3.9    3.0  3  APG6_N         Apg6 coiled-coil region
        2.1    8.8   9.1       0.39   11.1   0.5    3.7  5  LPP            Lipoprotein leucine-zipper
        2.8    8.7   9.7        4.1    8.2   0.9    3.4  3  DUF2203        Uncharacterized conserved protein (DUF2203)
        9.3    6.3  13.3        1.5    8.9   2.8    3.5  3  TMF_DNA_bd     TATA element modulatory factor 1 DNA binding


Domain annotation for each model (and alignments):
>> Dynamitin  Dynamitin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  247.9  10.2   1.8e-76   2.1e-73       1     388 []      16     460 ..      16     460 .. 0.87

  Alignments for each domain:
  == domain 1  score: 247.9 bits;  conditional E-value: 1.8e-76
   Dynamitin   1 qpDvYETpDlpeddstekesskeseseeelese.diersslnpneArskF.kgkkvdakgvDFsdriskkertgykasssreyeladege......... 88 
                 +pDvYETpDl++  st+++++ +++s++++es+ di+r +ln++eAr  F + + v+a++vDFsd+i  k r+ yk++s ++++ +++g+         
  EEA20131.1  16 APDVYETPDLTDGASTVPTTTIRTNSDSDDESNpDIDRNNLNTDEARLHFlRASGVSAREVDFSDTIATK-RKAYKSRSGHRRRRHGDGTeeigdisds 113
                 79******************999988866655416***************7777888*************.*****9988888888777789******* PP

   Dynamitin  89 ...eketleqklqRLqrEveeleeEvekakeaakeseeeeldpvela.eqleslqkqLeeleellgedsaasltdaqealakrllsqleefkeskaask 183
                     +e++e kl+RL+rE eel++E++++++a +++   ++d+ +   + +++l+k L+++      +s+ + +++++ l+++l + ++  +  +a +k
  EEA20131.1 114 dadGQESFEWKLARLRRETEELKAELQRREQAGQNDGRGNNDEDDYGdDGISELSKALDSI----HYSSTRANATSDAVLSRKLAAAVNPSNDPNAIEK 208
                 **99*****************************999666666665555*************....3333334555677777777777776665555555 PP

   Dynamitin 184 kkeksnkityelyyapeq....eksqqlakiaelekRLaeLEklvGlsses...ldelsanlkprplletlsrLeaklslL.................. 257
                 k++          ++p+     ++s  l+ +a+++ RL+++E+++G+ss s   + + +a+ + +p+l++l+ L +++++L                  
  EEA20131.1 209 KNT----------SSPATltapSSSGLLEHAASFDTRLTMMEAALGISSGSnpfFAAKDAQPQLQPVLPALDHLTSQITALtgtlggptasytaattst 297
                 443..........33333333348999*********************9983333344455569****************************9999999 PP

   Dynamitin 258 .qtahLDaierRlksllaeldelaekreaiekadaeg...............................qekKIneLYellkrldplspilPavldRLrs 324
                   ta+L+++++R+k l+a++++la++r+ + +  a +                               q +KI++LY +l+++ +l p+lP+vl+RLrs
  EEA20131.1 298 tTTAQLESLSSRIKRLTADAENLANARRRAGEVAARAppdspsvggdastssgatevnntesitqreeQAAKIQALYATLPTIQSLHPLLPSVLERLRS 396
                 8899***********************87754444449************************************************************* PP

   Dynamitin 325 LraLHeeAaefsqtLteleeeqkeiseelkslkelLekveeslkenletvkkNvesleerikkL 388
                 Lra+H++Aae+s+tL+ le++q+e+s+e+++++e+L+ ve+++ e++ ++kkN+e +  ++++L
  EEA20131.1 397 LRAIHASAAEASETLDALEKDQAEMSKEIEQWREGLNIVEQKVRESEISMKKNIEYVGPWVEAL 460
                 *************************************************************987 PP

>> Laminin_II  Laminin Domain II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.1       3.6   4.3e+03      36      57 ..     153     174 ..     124     197 .. 0.46
   2 ?    2.0   0.0      0.16   1.9e+02      11      37 ..     295     321 ..     254     335 .. 0.61
   3 ?   -0.3   0.0      0.82   9.8e+02      32      79 ..     350     398 ..     345     403 .. 0.63
   4 !   16.6   0.8   4.9e-06    0.0059       3      54 ..     402     450 ..     400     464 .. 0.80

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 3.6
                 XXXXXXXXXXXXXXXXXXXXXX CS
  Laminin_II  36 inrsveetnekvkdankairdA 57 
                  n++ +  ++ +++++ka+++ 
  EEA20131.1 153 NNDEDDYGDDGISELSKALDSI 174
                 3333333333344444444444 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.16
                 XXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Laminin_II  11 takevleqlaplsqnlentkeklsein 37 
                 t + + +ql+ ls +++++ +++++++
  EEA20131.1 295 TSTTTTAQLESLSSRIKRLTADAENLA 321
                 333344444444444444444444444 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.82
                 XXXXXXXXXXXXXXXXXXXXXX..XXXXXXXXXXX--TTTTTGGGHHHHH CS
  Laminin_II  32 klseinrsveetnekvkdanka..irdArrsvkkLeklapqLldklkelk 79 
                  + e+n++ e +++  ++a k+  +      ++ L  l+p +l++l++l+
  EEA20131.1 350 GATEVNNT-ESITQREEQAAKIqaLYATLPTIQSLHPLLPSVLERLRSLR 398
                 55666666.55665555544440033444578889999999999998886 PP

  == domain 4  score: 16.6 bits;  conditional E-value: 4.9e-06
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Laminin_II   3 elaaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankai 54 
                 + aaea+et+ + +++ a++s+++e+++e l+ ++++v+e +    +++k i
  EEA20131.1 402 ASAAEASETLDALEKDQAEMSKEIEQWREGLNIVEQKVRESEI---SMKKNI 450
                 5799*********************************887654...344444 PP

>> DUF948  Bacterial protein of unknown function (DUF948)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.0     0.032        38      28      81 ..     269     321 ..     260     329 .. 0.71
   2 ?    7.6   0.0    0.0039       4.7      21      65 ..     397     441 ..     389     462 .. 0.77

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.032
      DUF948  28 ldeaaatieelekqvdpilkevedllakvnelledvneklekvdplteavadlg 81 
                 ld+++++i+ l+  +++ +   +++++ + + ++++++ + ++++lt+ +++l+
  EEA20131.1 269 LDHLTSQITALTGTLGGPTASYTAATTSTTT-TAQLESLSSRIKRLTADAENLA 321
                 6777777777777777777777666666666.6777777777777777777765 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0039
      DUF948  21 llklkktldeaaatieelekqvdpilkevedllakvnelledvne 65 
                 l+ +   + ea++t++ lek+  +++ke+e+  +  n + + v+e
  EEA20131.1 397 LRAIHASAAEASETLDALEKDQAEMSKEIEQWREGLNIVEQKVRE 441
                 5666778899*********************99999996666655 PP

>> Spc24  Spc24 subunit of Ndc80
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   0.2     0.004       4.7      15      44 ..     120     153 ..     115     194 .. 0.82
   2 ?    2.3   0.0      0.16   1.9e+02      10      43 ..     293     326 ..     287     378 .. 0.72
   3 ?    5.0   0.2     0.023        28       9      45 ..     407     443 ..     400     457 .. 0.81

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.004
       Spc24  15 dleselesleselaelkeeleeleeesee....k 44 
                 + e +l +l+ e +elk+el+  e+ +++    +
  EEA20131.1 120 SFEWKLARLRRETEELKAELQRREQAGQNdgrgN 153
                 56778999*****************999955431 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.16
       Spc24  10 akelsdleselesleselaelkeeleeleeesee 43 
                 a  ++ ++++lesl+s+ ++l +  e+l + + +
  EEA20131.1 293 ATTSTTTTAQLESLSSRIKRLTADAENLANARRR 326
                 5556666667777777777777766666655544 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.023
       Spc24   9 iakelsdleselesleselaelkeeleeleeeseeke 45 
                 +++ l+ le++  ++++e ++++e l+ +e++  e+e
  EEA20131.1 407 ASETLDALEKDQAEMSKEIEQWREGLNIVEQKVRESE 443
                 56789999*******************9999988833 PP

>> FapA  Flagellar Assembly Protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1      0.56   6.7e+02     389     413 ..     120     144 ..     103     159 .. 0.67
   2 ?   11.7   0.4   5.8e-05      0.07     331     421 ..     355     448 ..     292     454 .. 0.75

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.56
        FapA 389 klkeeleeleeelkelkeeleskke 413
                 +++ +l+ l++e +elk+el+++++
  EEA20131.1 120 SFEWKLARLRRETEELKAELQRREQ 144
                 4455566666666666666666532 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 5.8e-05
        FapA 331 depelkeklkeleeeleeleeeleklkkk.......ikklpklkaekqlesekkeqlkklletkeklkeeleeleeelkelkeeleskkeeakikvnk 421
                 ++ e + +++e   ++++l + l ++++        +++l++l+a  +  +e +e+l+ l++++ ++++e+e+ +e l+ ++++++++    +i+ +k
  EEA20131.1 355 NNTESITQREEQAAKIQALYATLPTIQSLhpllpsvLERLRSLRAIHASAAEASETLDALEKDQAEMSKEIEQWREGLNIVEQKVRES----EISMKK 448
                 222233333333333333344444444446667777999999999999999***********************************99....344444 PP

>> DivIC  Septum formation initiator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.5       0.1   1.2e+02      32      49 ..     124     141 ..     119     147 .. 0.83
   2 ?   -1.5   0.0       1.8   2.2e+03      42      59 ..     192     208 ..     190     209 .. 0.85
   3 ?    6.9   0.1    0.0043       5.1      28      60 ..     298     330 ..     290     334 .. 0.83
   4 ?   -1.4   0.2       1.7     2e+03      18      34 ..     359     375 ..     354     381 .. 0.52
   5 ?   12.8   1.6   6.1e-05     0.073      17      65 ..     395     442 ..     388     453 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.1
                 HHHHHHHHHHHHHHHHCC CS
       DivIC  32 elaklkaeneeLeaevkd 49 
                 +la+l+ e eeL+ae+++
  EEA20131.1 124 KLARLRRETEELKAELQR 141
                 688999999999999865 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1.8
                 HHHHHHCC-XXXXXXXXX CS
       DivIC  42 eLeaevkdLksdedyiee 59 
                 +L+a v+   +d+++ie+
  EEA20131.1 192 KLAAAVNPS-NDPNAIEK 208
                 788889999.8******8 PP

  == domain 3  score: 6.9 bits;  conditional E-value: 0.0043
                 HHHHHHHHHHHHHHHHHHHHCC-XXXXXXXXXX CS
       DivIC  28 alqaelaklkaeneeLeaevkdLksdedyieer 60 
                 + +a+l++l+ ++++L+a  ++L + + +  e+
  EEA20131.1 298 TTTAQLESLSSRIKRLTADAENLANARRRAGEV 330
                 6799*******************8766665555 PP

  == domain 4  score: -1.4 bits;  conditional E-value: 1.7
                 HHHHHHHHHHHHHHHHH CS
       DivIC  18 aykqlkqeiaalqaela 34 
                 ++ q +++ a++qa +a
  EEA20131.1 359 SITQREEQAAKIQALYA 375
                 44445555555554444 PP

  == domain 5  score: 12.8 bits;  conditional E-value: 6.1e-05
                 XHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC-XXXXXXXXXXXXXXX CS
       DivIC  17 laykqlkqeiaalqaelaklkaeneeLeaevkdLksdedyieerARsel 65 
                 ++++++++  a+  ++l++l ++++e+ +e+++++ + + +e++ R e 
  EEA20131.1 395 RSLRAIHASAAEASETLDALEKDQAEMSKEIEQWREGLNIVEQKVR-ES 442
                 67889999***********************************999.44 PP

>> Jnk-SapK_ap_N  JNK_SAPK-associated protein-1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.2     0.041        49      46      75 ..     119     148 ..      90     185 .. 0.82
   2 ?    1.8   0.0      0.21   2.5e+02      45      76 ..     296     327 ..     291     337 .. 0.70
   3 ?    9.6   2.4   0.00084         1      24      94 ..     380     453 ..     350     464 .. 0.70

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.041
  Jnk-SapK_ap_N  46 eeeeaeleelreeleqLeteyerekelrkr 75 
                    e+ e +l +lr+e+e+L+ e++r+ ++ ++
     EEA20131.1 119 ESFEWKLARLRRETEELKAELQRREQAGQN 148
                    455667889999999999999999887655 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.21
  Jnk-SapK_ap_N  45 neeeeaeleelreeleqLeteyerekelrkra 76 
                    +   +a+le l+  +++L+ + e+ +++r+ra
     EEA20131.1 296 STTTTAQLESLSSRIKRLTADAENLANARRRA 327
                    45566777777777777777777777777765 PP

  == domain 3  score: 9.6 bits;  conditional E-value: 0.00084
  Jnk-SapK_ap_N  24 vkgLmPkvVkvLElLesl...asrneeeeaeleelreeleqLeteyerekelrkraeeeleeiedqweeerkel 94 
                    +++L P++ +vLE L sl   ++  +e +++l+ l+++  ++ +e e+ +e  +  e+++ e e +++++ + +
     EEA20131.1 380 IQSLHPLLPSVLERLRSLraiHASAAEASETLDALEKDQAEMSKEIEQWREGLNIVEQKVRESEISMKKNIEYV 453
                    56677777777777665511155566666667777777777777777777777777777777777766665554 PP

>> SlyX  SlyX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.7      0.11   1.3e+02      33      59 ..     125     151 ..     122     158 .. 0.77
   2 ?    2.5   0.0      0.19   2.2e+02      29      65 ..     299     336 ..     292     336 .. 0.72
   3 ?    8.4   1.1    0.0027       3.2      12      54 ..     404     446 ..     395     452 .. 0.88

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.11
                 HHHHHHHHHHHHHT-XXXXXXXXXXXX CS
        SlyX  33 idrlqrqlrllaerlkeleessgasea 59 
                 ++rl+r+ ++l+ +l+ +e++ +++++
  EEA20131.1 125 LARLRRETEELKAELQRREQAGQNDGR 151
                 78999*******999988888775554 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.19
                 HHHHHHHHHHHHHHHHHT-XXXXXXXXXXXX.XXXXXX CS
        SlyX  29 qqqqidrlqrqlrllaerlkeleessgasea.eeepPP 65 
                    q++ l  ++++l+   ++l+++ +++++ +   PP
  EEA20131.1 299 TTAQLESLSSRIKRLTADAENLANARRRAGEvAARAPP 336
                 56788888888888888888888887755555666666 PP

  == domain 3  score: 8.4 bits;  conditional E-value: 0.0027
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT-XXXXXXX CS
        SlyX  12 lafqedtieeLndvvaeqqqqidrlqrqlrllaerlkeleess 54 
                  a   +t+++L +  ae  ++i++ ++ l+ ++++++e e s+
  EEA20131.1 404 AAEASETLDALEKDQAEMSKEIEQWREGLNIVEQKVRESEISM 446
                 677889******************************9998775 PP

>> End3  Actin cytoskeleton-regulatory complex protein END3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   1.5   4.7e-05     0.056      76     131 ..      99     157 ..      48     195 .. 0.73
   2 ?   -2.8   0.0       4.9   5.8e+03     105     121 ..     302     318 ..     284     331 .. 0.49
   3 ?   -0.3   0.4      0.83   9.9e+02     155     182 ..     414     440 ..     389     452 .. 0.56

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 4.7e-05
        End3  76 rlGvgsks...ekgtdfsatkgtdweevrLkreLaeLeeklekveeeaekrkekerees 131
                 r G g+++    + +d   ++  +w   rL+re +eL+++l++ e++ ++  +++++e+
  EEA20131.1  99 RHGDGTEEigdISDSDADGQESFEWKLARLRRETEELKAELQRREQAGQNDGRGNNDED 157
                 23333332333455666666788999********************9998755555544 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 4.9
        End3 105 eLaeLeeklekveeeae 121
                 +L+ L ++++++ ++ae
  EEA20131.1 302 QLESLSSRIKRLTADAE 318
                 33333333333333333 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.83
        End3 155 leegegkskeknlksvkedietveeqVe 182
                 le++ +++ +k++++ +e ++ ve+ V+
  EEA20131.1 414 LEKD-QAEMSKEIEQWREGLNIVEQKVR 440
                 2222.22223455555555555555554 PP

>> MIP-T3_C  Microtubule-binding protein MIP-T3 C-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.1      0.95   1.1e+03      17      59 ..     129     171 ..     112     179 .. 0.57
   2 ?   -0.7   0.0         1   1.2e+03      40      70 ..     291     321 ..     271     323 .. 0.78
   3 ?   10.8   1.4   0.00029      0.35      39     126 ..     378     464 ..     349     465 .] 0.71

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.95
    MIP-T3_C  17 kkelekekaeaeeeekeaslaessakkeravsaseiekLresi 59 
                 ++e+e+ kae ++ e++ +  ++ +++e +  +  i++L + +
  EEA20131.1 129 RRETEELKAELQRREQAGQNDGRGNNDEDDYGDDGISELSKAL 171
                 4555555555555555544445555555555555555555555 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 1
    MIP-T3_C  40 sakkeravsaseiekLresiQkltksvnPLg 70 
                 +a+ + ++  +++e+L + i  lt  +  L+
  EEA20131.1 291 TAATTSTTTTAQLESLSSRIKRLTADAENLA 321
                 4556778888999999999999998777665 PP

  == domain 3  score: 10.8 bits;  conditional E-value: 0.00029
    MIP-T3_C  39 ssakkeravsaseiekLresiQkltksvnPLgklldfiqdDidsMqrELemWrseyrqqaeelaeerrateealeplkaqlaeleeaI 126
                  + ++ + +  s +e+Lr s+  +  s+      ld+ + D   M +E+e+Wr+  +  ++++ e +   ++++e +   ++ le+ I
  EEA20131.1 378 PTIQSLHPLLPSVLERLR-SLRAIHASAAEASETLDALEKDQAEMSKEIEQWREGLNIVEQKVRESEISMKKNIEYVGPWVEALEKRI 464
                 455667777777777777.477888888888999********************9999999998888777777777776666666665 PP

>> FlxA  FlxA-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.16   1.9e+02      31      75 ..     105     149 ..     100     163 .. 0.68
   2 ?    8.0   0.1    0.0024       2.9       5      39 ..     289     323 ..     286     331 .. 0.85
   3 ?    1.5   0.3      0.24   2.8e+02      42      66 ..     354     378 ..     344     383 .. 0.52
   4 ?   -0.7   0.4       1.2   1.4e+03      31      45 ..     409     424 ..     396     449 .. 0.51

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.16
        FlxA  31 kqLkelsesdeltkeekkkqqqliqaQIqqlqaQIaqlqqqqaek 75 
                 +++ ++s+sd+  +e  + +   +  + + l+a++++ +q  +++
  EEA20131.1 105 EEIGDISDSDADGQESFEWKLARLRRETEELKAELQRREQAGQND 149
                 666677777666666666777777777777777777776655554 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0024
        FlxA   5 sasssssssgsasqiasLqkQiknlqkqLkelses 39 
                 s +++++s+++++q++sL   ik+l+   ++l++ 
  EEA20131.1 289 SYTAATTSTTTTAQLESLSSRIKRLTADAENLANA 323
                 5567889999999*************999999886 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.24
        FlxA  42 ltkeekkkqqqliqaQIqqlqaQIa 66 
                   ++e  +q+++  a+Iq+l+a + 
  EEA20131.1 354 VNNTESITQREEQAAKIQALYATLP 378
                 3334444555555555666655555 PP

  == domain 4  score: -0.7 bits;  conditional E-value: 1.2
        FlxA  31 kqLkelses.deltke 45 
                 + L+ l ++  e++ke
  EEA20131.1 409 ETLDALEKDqAEMSKE 424
                 3333333332222222 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.4     0.018        21      46      75 ..     115     144 ..      79     156 .. 0.65
   2 ?   -0.6   0.1       1.5   1.8e+03      75      95 ..     301     321 ..     288     333 .. 0.50
   3 ?    8.6   3.9    0.0021       2.5      50      98 ..     391     439 ..     348     449 .. 0.76

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.018
      APG6_N  46 deeleeleeeleklekeeeelleeLkelek 75 
                  +  e+ e +l++l++e eel +eL++ e+
  EEA20131.1 115 ADGQESFEWKLARLRRETEELKAELQRREQ 144
                 444556666677777777777777777665 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 1.5
      APG6_N  75 kereeleaelaaleeeleale 95 
                 ++ e+l + ++ l++ +e+l 
  EEA20131.1 301 AQLESLSSRIKRLTADAENLA 321
                 233333333333333333333 PP

  == domain 3  score: 8.6 bits;  conditional E-value: 0.0021
      APG6_N  50 eeleeeleklekeeeelleeLkelekereeleaelaaleeelealeeee 98 
                  e  ++l+++++  +e+ e L++lek ++e+ +e+++ +e l+ +e++ 
  EEA20131.1 391 LERLRSLRAIHASAAEASETLDALEKDQAEMSKEIEQWREGLNIVEQKV 439
                 44556799999**************************999888888765 PP

>> LPP  Lipoprotein leucine-zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       9.8   1.2e+04      11      27 ..     127     143 ..     124     148 .. 0.61
   2 ?   -0.9   0.0       1.8   2.2e+03      23      41 ..     164     182 ..     154     190 .. 0.61
   3 ?   -2.7   0.0       6.7     8e+03       2      12 ..     269     279 ..     269     282 .. 0.78
   4 ?   11.1   0.5   0.00033      0.39       6      40 ..     300     334 ..     297     335 .. 0.95
   5 ?    0.3   0.1      0.81   9.7e+02       7      28 ..     409     430 ..     404     437 .. 0.66

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 9.8
         LPP  11 qLkskvdqlssdvnsak 27 
                 +L ++ ++l+++++  +
  EEA20131.1 127 RLRRETEELKAELQRRE 143
                 56666667777666555 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 1.8
         LPP  23 vnsakaaaqaakeEAaRAN 41 
                 ++++++a++++     RAN
  EEA20131.1 164 ISELSKALDSIHYSSTRAN 182
                 4444555555555555555 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 6.7
         LPP   2 ldeLssqVsqL 12 
                 ld L+sq+ +L
  EEA20131.1 269 LDHLTSQITAL 279
                 57899999887 PP

  == domain 4  score: 11.1 bits;  conditional E-value: 0.00033
         LPP   6 ssqVsqLkskvdqlssdvnsakaaaqaakeEAaRA 40 
                 ++q+++L+s ++ l++d++++++a   a e AaRA
  EEA20131.1 300 TAQLESLSSRIKRLTADAENLANARRRAGEVAARA 334
                 5799******************************9 PP

  == domain 5  score: 0.3 bits;  conditional E-value: 0.81
         LPP   7 sqVsqLkskvdqlssdvnsaka 28 
                 + + +L+++++++s+++++ ++
  EEA20131.1 409 ETLDALEKDQAEMSKEIEQWRE 430
                 4556677777777777666554 PP

>> DUF2203  Uncharacterized conserved protein (DUF2203)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.2       0.3   3.6e+02      22      51 ..     125     156 ..     118     185 .. 0.64
   2 ?    2.9   0.2      0.14   1.7e+02      49      70 ..     297     318 ..     252     384 .. 0.55
   3 ?    8.2   0.9    0.0034       4.1       5      78 ..     380     448 ..     376     455 .. 0.77

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.3
     DUF2203  22 lralrkeleeleeeleeakaeaekse..aael 51 
                 l++lr+e eel++el++ +++ ++++   + +
  EEA20131.1 125 LARLRRETEELKAELQRREQAGQNDGrgNNDE 156
                 56788999999999999888876555542222 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.14
     DUF2203  49 aeleaeleeleaeieelveeie 70 
                 ++  a+le+l+++i++l++  e
  EEA20131.1 297 TTTTAQLESLSSRIKRLTADAE 318
                 3333333333333333332222 PP

  == domain 3  score: 8.2 bits;  conditional E-value: 0.0034
     DUF2203   5 leeAnalLpllkelleelralrkeleeleeeleeakaeaekseaaeleaeleeleaeieelveeieelGvevkd 78 
                 ++  + lLp + e+l+ lra  + ++e++e l++ +++     +ae+ +e+e+ ++ ++ + ++++e  + +k 
  EEA20131.1 380 IQSLHPLLPSVLERLRSLRAIHASAAEASETLDALEKD-----QAEMSKEIEQWREGLNIVEQKVRESEISMKK 448
                 55556789999999999999999999999988888877.....6777888888888887777777777777764 PP

>> TMF_DNA_bd  TATA element modulatory factor 1 DNA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.5      0.31   3.7e+02      54      72 ..     123     141 ..     115     145 .. 0.66
   2 ?    1.2   0.1      0.31   3.7e+02      47      67 ..     301     321 ..     294     329 .. 0.60
   3 ?    8.9   2.8    0.0012       1.5      30      72 ..     406     448 ..     398     449 .. 0.91

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.31
  TMF_DNA_bd  54 kkleklekeleeleerlke 72 
                  kl++l +e eel+++l++
  EEA20131.1 123 WKLARLRRETEELKAELQR 141
                 5667777777777776665 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.31
  TMF_DNA_bd  47 keikelkkkleklekeleele 67 
                  ++++l++++++l+ + e+l 
  EEA20131.1 301 AQLESLSSRIKRLTADAENLA 321
                 455566666666555555554 PP

  == domain 3  score: 8.9 bits;  conditional E-value: 0.0012
  TMF_DNA_bd  30 klnntikkLrkknkelekeikelkkkleklekeleeleerlke 72 
                 + ++t++ L k+ +e+ kei++  + l+ +e+++ e e ++k+
  EEA20131.1 406 EASETLDALEKDQAEMSKEIEQWREGLNIVEQKVRESEISMKK 448
                 6789********************************9999885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (465 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1151  (0.0641977); expected 358.6 (0.02)
Passed bias filter:                      597  (0.033298); expected 358.6 (0.02)
Passed Vit filter:                        70  (0.00390429); expected 17.9 (0.001)
Passed Fwd filter:                        27  (0.00150594); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.76u 0.32s 00:00:01.08 Elapsed: 00:00:00.49
# Mc/sec: 2868.46
//
Query:       EEA20132.1  [L=229]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (229 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       278  (0.0155056); expected 358.6 (0.02)
Passed bias filter:                      244  (0.0136092); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.44
# Mc/sec: 1577.30
//
Query:       EEA20133.1  [L=591]
Description: methylmalonate-semialdehyde dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
   5.3e-135  450.5   0.3   6.4e-135  450.2   0.3    1.1  1  Aldedh     Aldehyde dehydrogenase family
  ------ inclusion threshold ------
       0.15   11.0   0.0       0.23   10.5   0.0    1.2  1  LuxC       Acyl-CoA reductase (LuxC)
       0.58    8.9   2.3       0.83    8.4   2.3    1.1  1  DUF3537    Protein of unknown function (DUF3537)


Domain annotation for each model (and alignments):
>> Aldedh  Aldehyde dehydrogenase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  450.2   0.3  1.1e-138  6.4e-135       2     462 .]     105     569 ..     104     569 .. 0.98

  Alignments for each domain:
  == domain 1  score: 450.2 bits;  conditional E-value: 1.1e-138
                 ET-SSSE.EEEEETTTCEEEEEEE-B-HHHHHHHHHHHHHHHHHHTTS-HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH---HHHHHHHHHHHHHHHHH CS
      Aldedh   2 veseset.ievinPatgeviakvpaataedvdaavaaAkeafkawaklpaeeRaeiLrkaadlleerkeelaeletletGkplaearaeveeaidvlry 99 
                 v+s++++ i+ ++Pat++ +++vp++t e+++aava+A++af+aw+++++  R+ei+ k+ +l++++ ++la+ +tle+Gk++a+a+++v + ++v++ 
  EEA20133.1 105 VTSKATEwIDLHDPATNNLVTRVPQSTDEELKAAVASAEKAFPAWRATSIIARQEIMFKFVSLIRRDWDRLAASITLEQGKTFADAKGDVLRGLQVAET 203
                 66677566******************************************************************************************* PP

                 HHHHHHHHSEEEEEECTTEEEEEEEEE-SEEEEEE-SSSCCHHHHHHHHHHHHTT-EEEEEE-TTSHHHHHHHHHHHHHTTS-TTSEEE--SSTCCHHH CS
      Aldedh 100 yaelaeklegevlpssegklalvrrePlGvvgaItPWNfPlllaawklapalaaGNtvvlKPaeetplsalllaelfeeaglPkgvlnvvtgsgsevge 198
                 +++  ++l+g++l++++++++ ++rePlGvv+aI+P+NfP+++++w +  a ++GNt+v+KP+e+ p  a++lael++eag+P+gv+n+v+g  +++ +
  EEA20133.1 204 ACGITSQLTGDILEVAKDMETRSYREPLGVVAAICPFNFPAMIPLWCIPVATITGNTIVIKPSERDPGAAMILAELAREAGFPPGVINIVHG-AHKTVN 301
                 ***************99***************************************************************************.88999* PP

                 HHHH-TTESEEEEES-HHHHHHHHHHHHCTTSEEEEEE---EEEEE-TTSHHHHHHHHHHHHHHGGGGTSTTSEEEEEEEHHHHHHHHHHHHHHHHT-- CS
      Aldedh 199 alvehpevdkvsftGstevgrkiakaaaknlkrvtlElGGknplivledaDldkaveaivkgafgnaGQvCiaasrllvqesiydefveklveaakklk 297
                  ++++p ++++sf+G+++ g+ i+++ ++n krv++ lG+kn++ vl+d + ++a++ai+ +afg aGQ+C+a s l+   ++ +e++ +l+e+ak+l+
  EEA20133.1 302 FILDEPAIKAISFVGGNKAGEYIYTRGSANGKRVQANLGAKNHATVLPDSNKNHALNAIAGAAFGAAGQRCMALSTLVMVGET-KEWLPELAERAKQLQ 399
                 **************************999**********************************************99999888.89************* PP

                 BS-TTSTT-SB---SSHHHHHHHHHHHHHHHHTTSEEEE-TT.E.SB-SSSTTEE--EEEES-TTTSHHHHS---SSEEEEEEESSHHHHHHHHHSSSE CS
      Aldedh 298 vgdpldedtdvGPliseaqlekvekyveeakeegaklllGge.reeaglekgyfvePtvlanvtpdmriaqeEiFGPVlsvikfkdeeeaieiaNdtey 395
                 v  +++   d+GP+is+++ +++e+++++a++ega++ll+g+  + +++ +g++++Pt+++nvtpdm+++++EiFGPVl+ + ++++++ai++ N++ey
  EEA20133.1 400 VNGGFEAGADLGPVISPQSKKRIEDLIASAEKEGATILLDGRgYKPEKYPNGNWIAPTIITNVTPDMTCYKQEIFGPVLVCLNVETLDDAIALTNANEY 498
                 ******************************************9899***************************************************** PP

                 ESEEEEE-SBHHHHHHHHHHS-SSEEEESSSST--TTTSEB--CGGGEES....-BSHHHHHHHTEEEEEE CS
      Aldedh 396 GLaagvftkdleraervaerleaGnvyiNdsttgaaealpfgGvkqSglG....reggkegleeytevktv 462
                 G++a++ft++ + a r+ +++eaG+++iN ++ +   ++ f+G k+S  G     + gk gl++yt+ ktv
  EEA20133.1 499 GNGAAIFTTSGSCASRFQKNIEAGQLGINVPIPVPLPMFSFTGNKKSIAGggasTFYGKPGLQFYTQQKTV 569
                 ***********************************************99988888899***********97 PP

>> LuxC  Acyl-CoA reductase (LuxC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   3.8e-05      0.23      87     137 ..     228     278 ..     214     335 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 3.8e-05
        LuxC  87 aqprglvlhvlsgNvp.llpvmsilqglLvknvnllkvSssdpflaaallks 137
                 + p g+v  + + N p ++p++ i  + +++n +++k+S  dp++a+ l ++
  EEA20133.1 228 REPLGVVAAICPFNFPaMIPLWCIPVATITGNTIVIKPSERDPGAAMIL-AE 278
                 5799**********9945799**********************987655.44 PP

>> DUF3537  Protein of unknown function (DUF3537)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   2.3   0.00014      0.83     268     328 ..      29      89 ..      23     125 .. 0.66

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00014
     DUF3537 268 vvgllicLrsAakitHraqaitslaskWhalatiesaeaekeepsssaaelea.aksassld 328
                 v+g     +s a i+  +q+++s++s+ h+ +t++ ++++++  ++saa++++   +++  +
  EEA20133.1  29 VAGTWTTSKSMANISPLSQSVVSHTSRRHIHVTARRSSQQQQYGTQSAASTTTeYPTSH-EQ 89 
                 6667777789999*********************9988766655555554444222222.22 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (591 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       584  (0.0325729); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.44
# Mc/sec: 4027.80
//
Query:       EEA20134.1  [L=563]
Description: calnexin [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.3e-167  557.3  18.3   1.6e-167  557.0  18.3    1.1  1  Calreticulin    Calreticulin family
  ------ inclusion threshold ------
       0.29   11.5   5.5       0.74   10.2   5.5    1.7  1  MT0933_antitox  MT0933-like antitoxin protein


Domain annotation for each model (and alignments):
>> Calreticulin  Calreticulin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  557.0  18.3  1.8e-171  1.6e-167       1     367 []      52     419 ..      52     419 .. 0.99

  Alignments for each domain:
  == domain 1  score: 557.0 bits;  conditional E-value: 1.8e-171
  Calreticulin   1 fveqFeeeeelekrwikskakked....eeakYkgkwsveepkklkglegdkgLvlkskakhhaisaklekpiklkkkdLvvqYevklqeglecgga 93 
                   f+eqF++  +++krw++s+akked    e ++Y g+wsveep+++kg+egdkgLvlk+ a+hhaisak++k+i++k k+LvvqYevk q++l cgga
    EEA20134.1  52 FLEQFTD--DWDKRWTPSHAKKEDstseEDWAYVGEWSVEEPTVFKGIEGDKGLVLKNPAAHHAISAKFPKKIDNKGKTLVVQYEVKPQNSLICGGA 146
                   79****8..9**********99999999999****************************************************************** PP

  Calreticulin  94 yikLlseeeekdleefsdktpytimFGpdkcgstnkvhfilrkknpktgeieekhlkkppklkkdklthLytLilkpdntfeiridgkvvksgnlle 190
                   y+kLl+e+++ ++eefs+ +py imFGpdkcg+tnkvhfi+++knpktg++eekh+++pp  +++k+t++ytLi+kpd+tfei+i+g++vk+g+lle
    EEA20134.1 147 YLKLLQENKKLHAEEFSNASPYVIMFGPDKCGATNKVHFIFKHKNPKTGKYEEKHMTNPPVPHTEKTTSVYTLIVKPDQTFEILINGDNVKNGTLLE 243
                   ************************************************************************************************* PP

  Calreticulin 191 dfeppvnppkeidDpedkkPedWddrekipDpeavkPedwdekapekipdpeavkPedWledepelipdpeaekPedwdeeedgeweaplikNpkCe 287
                   df+p+vnppk+idDp+dkkP+dW+d++ki+Dpea+kPedwde+ap +i+d ea+kP+dWle+ep +i dpeaekPedwd+eedg+w+ap+i+Np+C+
    EEA20134.1 244 DFSPAVNPPKQIDDPKDKKPSDWVDEAKIADPEATKPEDWDEEAPFEIVDLEATKPDDWLENEPLTIADPEAEKPEDWDDEEDGDWIAPTIPNPACA 340
                   ************************************************************************************************* PP

  Calreticulin 288 easgCgkwkpplikNpkYkGkwkaplienpnYkGeWkprkipnpdyfedkkplkklepigaigfelwsmskdilfdniyi 367
                   ++sgCg+w++p++kNp+YkGkw+apli+np+YkG W+prki+np+yfedk+p +++ep+gaigfelw+m++dilfdniyi
    EEA20134.1 341 DVSGCGPWTAPMKKNPDYKGKWSAPLIDNPKYKGPWAPRKIANPEYFEDKTP-SNFEPMGAIGFELWTMQNDILFDNIYI 419
                   ****************************************************.99************************8 PP

>> MT0933_antitox  MT0933-like antitoxin protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   5.5   8.3e-05      0.74      17      48 ..     523     553 ..     521     554 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 8.3e-05
  MT0933_antitox  17 qgiDKAgdavddktGgKysdkIdkgqdaakda 48 
                     ++ +K + a+  +t++K +++++++ daak+a
      EEA20134.1 523 KAAEKGKAAAT-ATKEKTAQAVSSATDAAKGA 553
                     56788888888.******************87 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (563 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       593  (0.0330749); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3839.34
//
Query:       EEA20135.1  [L=254]
Description: class II aldolase/adducin domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.8e-45  153.3   0.0    8.1e-45  153.0   0.0    1.1  1  Aldolase_II  Class II Aldolase and Adducin N-terminal domain


Domain annotation for each model (and alignments):
>> Aldolase_II  Class II Aldolase and Adducin N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  153.0   0.0   4.5e-49   8.1e-45       3     185 ..      36     238 ..      34     239 .. 0.90

  Alignments for each domain:
  == domain 1  score: 153.0 bits;  conditional E-value: 4.5e-49
                  HHHHHHHHHHTTSSCTTBCEEEEEETSTTEEEEEBTSS-GGGHTGGGEEEEETTSCEEEEC......ECSSSTB-TTHHHHHHHHHH-TT-SEEEEE- CS
  Aldolase_II   3 laeasrllarrglvegtgGniSvrvpeedsflitpsgvdfeeltaedlvvvdldsgevveg......kekggkpssetplHlaiykarpdaravvHtH 94 
                  + e++r++++ g+v+gtgG +S+r+  +d+++i+psgv++e +++e+++v+++ + + +        k k++kps +tpl+l ++++   a++++HtH
   EEA20135.1  36 IPEMCRKFYTWGWVTGTGGGTSIRH--GDHIFIAPSGVQKELIQPENMFVMQFPTPKYPPSerkyirKPKNLKPSDCTPLFLTAFER--GAGCCIHTH 129
                  7899********************4..69***********************9544333224677777899***************8..********* PP

                  -HHHHHHHTCC................STSCHCCSSHHHHC.HSS.SEEEEES-SSTTCHHHHHHHHHHHH.H.S-SEEEETTTEEEEEESSHHHHHH CS
  Aldolase_II  95 spaavalsala................gkeglppltqeaaklllg.devpvipyaapgteelgealaealk.e.dakavllrnHGlltvGetleeAva 173
                  s++av++++l+                +++g+p+   ++++ + +  ++p+i++++++++++ e l++a++ + d+ avl+r+HG++++G+t ++A++
   EEA20135.1 130 SQWAVLVTLLVereygkegyfeisnieQIKGIPKGKGKGMHNYHDtLRIPIIENTPFEEDLT-EGLERAINaNpDTYAVLVRRHGIYVWGDTPAKAKT 226
                  ********766***************9999999977777777766899********997777.*******9647999********************* PP

                  HHHHHHHHHHHH CS
  Aldolase_II 174 laetleeaaeiq 185
                  ++e l+++++++
   EEA20135.1 227 QCESLDWLFQLA 238
                  *********987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (254 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       382  (0.0213063); expected 358.6 (0.02)
Passed bias filter:                      357  (0.0199119); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.30s 00:00:00.76 Elapsed: 00:00:00.46
# Mc/sec: 1645.51
//
Query:       EEA20136.1  [L=575]
Description: vacuolar protein sorting-associated protein Vps5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.3e-88  295.2   3.1    5.7e-88  294.4   3.1    1.3  1  Vps5      Vps5 C terminal like
    5.1e-25   87.6   0.0    1.3e-24   86.3   0.0    1.7  1  PX        PX domain
     0.0093   15.7   4.6       0.34   10.6   1.0    2.4  2  BAR_3     BAR domain of APPL family
  ------ inclusion threshold ------
       0.23   10.7   7.0      0.077   12.3   3.3    2.0  2  DUF3450   Protein of unknown function (DUF3450)


Domain annotation for each model (and alignments):
>> Vps5  Vps5 C terminal like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  294.4   3.1   1.3e-91   5.7e-88       4     234 ..     289     518 ..     285     520 .. 0.96

  Alignments for each domain:
  == domain 1  score: 294.4 bits;  conditional E-value: 1.3e-91
        Vps5   4 lfkkltssisksstkfeEqDewFedkkqeldslesqLkkLykaiellvsqrkelasataelakslesLaslelskslsralsqlaeveerikellerqa 102
                 ++++l+ s+     kf E+D+wF+d+k +ld+le+qLk L+kai+++v+qrk la+a++++++sl++La++els+ ls  l+ l+e++ ri+el+erqa
  EEA20136.1 289 MLSSLGISVGG-GGKFIEHDDWFHDRKLYLDALENQLKALMKAIDTVVAQRKGLAEAAGDFSASLHALAAVELSPVLSGPLEGLSELQLRIRELYERQA 386
                 44555555555.89************************************************************************************* PP

        Vps5 103 eqdvltLgetideylrligsvksvfeqRvklwqkwqsaeqelskkkeqleKlekaaksqqdklqqlkkeveelerkvqeaekeFeeisetikkElerFe 201
                 +qdvltLg+tidey+rligs+k++f+qR+k +++w+ ae+el+k+++++eKl +++ksqqd+++q++++v+++erkv++ +  Fe++++ +++ElerFe
  EEA20136.1 387 QQDVLTLGITIDEYIRLIGSIKTAFSQRQKSFHSWHAAEAELQKRRHTQEKLLRQGKSQQDRINQINADVADAERKVHQSRLLFEDMGRLMRNELERFE 485
                 *************************************************************************************************** PP

        Vps5 202 tervedfknvvekyLesaiesqkevielWetfl 234
                 +e+vedfk+ ve++Le a+e+qke+ielWe+fl
  EEA20136.1 486 KEKVEDFKSGVETFLEGAVEAQKELIELWESFL 518
                 *******************************98 PP

>> PX  PX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.3   0.0   2.9e-28   1.3e-24       2     112 ..     154     266 ..     153     267 .. 0.95

  Alignments for each domain:
  == domain 1  score: 86.3 bits;  conditional E-value: 2.9e-28
                 SEEEEEEEEEEEETTSSEEEEEEEEEETTS.....SSEEEEEEEHHHHHHHHHHHHHHHTTSTSTSSSTSGSSSSSCTTSHHHHHHHHHHHHHHHHHHH CS
          PX   2 dlaqvsvleretsgskkhsyylyevelktg.....akewtvkRrYsdFeeLhskLlrkfprvkiPplPkkvlfgsvrkkdeefiekrrkgLeeyLqrll 95 
                 +++ ++v ++++ g+  +s ++y++++kt      + e++v+RrY+dF + +++L ++ p+v++Pp P+k+ +g+   +d++f+e+rr++Le+++++++
  EEA20136.1 154 PTFNITVGDPHKVGDLTSSHIVYQIRTKTTskayrQPEFEVSRRYRDFLWIYNQLHSNNPGVVVPPPPEKQAVGR---FDTNFVESRRAALERMINKIA 249
                 56789999***999999999999999999999******************************************9...********************* PP

                 TSCHHHHSHHHHHHHHS CS
          PX  96 nhpelrnsevlteFLev 112
                  hp l+ + +l+ FLe+
  EEA20136.1 250 AHPILQHDADLKIFLES 266
                 ***************97 PP

>> BAR_3  BAR domain of APPL family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.6   1.0   7.5e-05      0.34      24     143 ..     317     431 ..     311     468 .. 0.60
   2 !    6.3   0.2    0.0016       7.1      89     124 ..     465     500 ..     459     513 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 7.5e-05
       BAR_3  24 leelekklkkllKlckrlieagkaysaaqkqfaqsLrelkkeskgdeetdesLkkfsellqelenehtilldqaqrsikkpLekFrkedlkevkekkkk 122
                 l+ le++lk l+K++  +++  k + +a   f+ sL+ l+    +  +++  L+ +sel   + + +++   qaq+  +  L   + e ++ +   k +
  EEA20136.1 317 LDALENQLKALMKAIDTVVAQRKGLAEAAGDFSASLHALAAVELS-PVLSGPLEGLSELQLRIRELYER---QAQQD-VLTLGITIDEYIRLIGSIKTA 410
                 789**********************************99876654.45555555555554444444443...33333.333444444455545555555 PP

       BAR_3 123 Fdkesekleaaleknaqlskk 143
                 F + ++++ +  +  a+l+k+
  EEA20136.1 411 FSQRQKSFHSWHAAEAELQKR 431
                 555555555544444444444 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0016
       BAR_3  89 ehtilldqaqrsikkpLekFrkedlkevkekkkkFd 124
                 + + l++ + r ++++Le+F ke+++ +k   + F 
  EEA20136.1 465 QSRLLFEDMGRLMRNELERFEKEKVEDFKSGVETFL 500
                 556799***********************9988886 PP

>> DUF3450  Protein of unknown function (DUF3450)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.1      0.31   1.4e+03      74     104 ..     317     347 ..     312     391 .. 0.59
   2 ?   12.3   3.3   1.7e-05     0.077      13     119 ..     406     517 ..     401     521 .. 0.85

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.31
     DUF3450  74 vasqeqeiasleeqieeieeierelvpllek 104
                 ++++e++++ l + i+ + + +++l     +
  EEA20136.1 317 LDALENQLKALMKAIDTVVAQRKGLAEAAGD 347
                 4555555555555555555555555544444 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 1.7e-05
     DUF3450  13 alaatldqalkeaekavaaaaqsqkk...idklddekqellaeyralkeeleslevyneqlerlvasqeqei.aslee.qieeieeierelvpllekmi 106
                 +++++++q +k   +++aa+a+ qk+   ++kl ++ ++ +++++++++ ++++e +  q + l +++ + + ++le+ ++e++e  +++++ +le  +
  EEA20136.1 406 SIKTAFSQRQKSFHSWHAAEAELQKRrhtQEKLLRQGKSQQDRINQINADVADAERKVHQSRLLFEDMGRLMrNELERfEKEKVEDFKSGVETFLEGAV 504
                 556778899999999*********97555789999***************************999999776525666656889**************** PP

     DUF3450 107 drLeqfveldlPf 119
                 ++ ++++el   f
  EEA20136.1 505 EAQKELIELWESF 517
                 ******9985555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (575 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1033  (0.0576162); expected 358.6 (0.02)
Passed bias filter:                      476  (0.0265492); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.60u 0.34s 00:00:00.94 Elapsed: 00:00:00.48
# Mc/sec: 3613.32
//
Query:       EEA20137.1  [L=112]
Description: hypothetical protein PMAA_039980 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (112 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       380  (0.0211947); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.47
# Mc/sec: 723.58
//
Query:       EEA20138.1  [L=189]
Description: 50S ribosomal protein L36, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.017   16.0   0.9      0.031   15.2   0.9    1.4  1  Pup       Pup-like protein


Domain annotation for each model (and alignments):
>> Pup  Pup-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   0.9   1.7e-06     0.031      13      49 ..     143     179 ..     130     187 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1.7e-06
         Pup  13 keeveeaeaeaeassevkerkeelsedvDdlLDeIDe 49 
                  ++ ++a a+a+a+++++++++el+e+ D+lLD I +
  EEA20138.1 143 MKQAQDAAADAAAEKATAQEEAELQEEEDSLLDLISS 179
                 2455788899999999999**************9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (189 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1282  (0.0715043); expected 358.6 (0.02)
Passed bias filter:                      608  (0.0339115); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 1342.73
//
Query:       EEA20139.1  [L=205]
Description: oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.1e-25   90.5   0.0    1.9e-25   89.7   0.0    1.4  1  Flavin_Reduct  Flavin reductase like domain


Domain annotation for each model (and alignments):
>> Flavin_Reduct  Flavin reductase like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.7   0.0   1.1e-29   1.9e-25       1     151 [.       1     197 [.       1     201 [. 0.74

  Alignments for each domain:
  == domain 1  score: 89.7 bits;  conditional E-value: 1.1e-29
                    HTTS-EE-EEEEE.EE..TTEEE......EEEESSEEEEETTT.TEEEEEEETTSHHHHHHHHHSEEEEEEEBC..CGHHHHHHTCS...SCCCCC CS
  Flavin_Reduct   1 mrrvaqpvavvttsvp..ptspl......gatlssftslsldP.plvafslrlpsstadalkeagefvinllse..sqealadafsqksgprtddk 85 
                    mr +++pva+vt+s p  +   +      g+t+ssf +++l+P p+++f++r ps+t+ a++++g+f ++ll++  s + la++fs+++ + + d+
     EEA20139.1   1 MRCIPHPVAIVTASSPspT--TNqkpiprGMTVSSFNTVTLHPkPIITFNVRQPSETLAAIQSSGRFLVHLLAPtaSMARLARNFSRGNVNVDLDR 94 
                    99************99651..444566669********************************************633355*******999666666 PP

                    CCCCCCEEECT.......................CCCS......EEETTCSEEEEEEEEE..EECCTTEEEEEEEEEEE.EESTTECTT....... CS
  Flavin_Reduct  86 sifagltwees.......................ptga......pallgalasleCqvvg..svelgdhelfigeVvav.kvgddadee....... 142
                      f+ ++ +e                        +          + ++  + leC+ +   sv++ dh +++g+V ++   g +a +e       
     EEA20139.1  95 --FEYIEHGEMdnnggstilpqlirrrinnndndN--EticddnKLEEDFTFILECEYLPekSVQVYDHMIVLGNVKRIiAPGPNALDEgkrhtre 186
                    ..556665555555555555555555444444431..044555477799*******9988668***************943333455454555555 PP

                    ..BEECCCCCE CS
  Flavin_Reduct 143 ..pLlywrrry 151
                       L+y++ r+
     EEA20139.1 187 dfCLMYADTRF 197
                    55566666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (205 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       393  (0.0219198); expected 358.6 (0.02)
Passed bias filter:                      359  (0.0200234); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.44
# Mc/sec: 1392.36
//
Query:       EEA20140.1  [L=1022]
Description: ubiquitination network signaling protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        1.7    8.9  11.5       0.85    9.9   2.5    2.9  3  DUF1612   Protein of unknown function (DUF1612)


Domain annotation for each model (and alignments):
>> DUF1612  Protein of unknown function (DUF1612)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0    0.0019        34      38      68 ..     310     340 ..     297     383 .. 0.78
   2 ?   -4.2   0.4         1   1.8e+04      79     100 ..     405     425 ..     399     439 .. 0.54
   3 ?    9.9   2.5   4.7e-05      0.85      57     116 ..     712     771 ..     689     785 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.0019
     DUF1612  38 aWeelevlqrqpwlgrlLaaalLrqrgktas 68 
                  ++++e+    +wl +lLa  +L q+g++ +
  EEA20140.1 310 EFRRMEPQTSPSWLRSLLAIHILAQAGTAMA 340
                 568999*99******************8754 PP

  == domain 2  score: -4.2 bits;  conditional E-value: 1
     DUF1612  79 avrrerrrardretRllailea 100
                 +++++rr+a++  +R + +  a
  EEA20140.1 405 NAKKRRRQANQVRSR-QPFWAA 425
                 455555555555554.344444 PP

  == domain 3  score: 9.9 bits;  conditional E-value: 4.7e-05
     DUF1612  57 aalLrqrgktasHLaalnlglkavrrerrrardretRllailealeaaaeaglkeldRls 116
                 + lL  r+ ++  La+l+  l ++ ++r r ++r+tRl    e + +a + gl e +R +
  EEA20140.1 712 EELLNARTSVSRDLATLESDLATAVQKRDRLQSRKTRLNEQYERIISANAQGLNERERRA 771
                 5789999************************************************99964 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1022 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2053  (0.114507); expected 358.6 (0.02)
Passed bias filter:                      584  (0.0325729); expected 358.6 (0.02)
Passed Vit filter:                        82  (0.0045736); expected 17.9 (0.001)
Passed Fwd filter:                        28  (0.00156172); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 1.19u 0.34s 00:00:01.53 Elapsed: 00:00:00.56
# Mc/sec: 5455.75
//
Query:       EEA20141.1  [L=311]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.8e-31  107.3   0.1    1.1e-30  106.7   0.1    1.3  1  4HBT_2       Thioesterase-like superfamily
    3.9e-05   23.9   0.0    0.00015   22.1   0.0    2.0  1  4HBT         Thioesterase superfamily
  ------ inclusion threshold ------
      0.053   12.8   0.2       0.19   11.0   0.1    1.8  2  Acyl-ACP_TE  Acyl-ACP thioesterase


Domain annotation for each model (and alignments):
>> 4HBT_2  Thioesterase-like superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.7   0.1   1.8e-34   1.1e-30       1     123 []     129     265 ..     129     265 .. 0.91

  Alignments for each domain:
  == domain 1  score: 106.7 bits;  conditional E-value: 1.8e-34
      4HBT_2   1 vrpndvDlnghlnnarylryleearvkfle..........rtglksrsiarrgiglilssahvryrrplkfpdrltvefrvid.....idaktliiehr 84 
                 v ++d+D +gh+nn++y+ry+e+arv++++          +t+ +++++ ++giglil+s++++y++p+++pd++tv++r+++      ++++++ e+ 
  EEA20141.1 129 VVWGDMDSMGHINNVAYVRYAETARVNLMHnyatnidpahQTE-WINTVGNKGIGLILQSIKIDYKFPMTWPDKITVYHRLTKdpsdtLNKSYFQQEAL 226
                 78***************************98877777754444.58999999*****************************777999************ PP

      4HBT_2  85 flsnadgkk..aarveerivvmdygk.rskkapvPpellkal 123
                 +ls  ++k+  aarv+e++ ++dy++ r k+++ P+++l+++
  EEA20141.1 227 ILS--ECKQrpAARVIEQNYLYDYTQlR-KTSTAPEFILRQF 265
                 ***..666666***************66.********99886 PP

>> 4HBT  Thioesterase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.1   0.0   2.5e-08   0.00015       1      57 [.     137     209 ..     137     210 .. 0.97

  Alignments for each domain:
  == domain 1  score: 22.1 bits;  conditional E-value: 2.5e-08
                 TSSB-HHHHHHHHHHHHHHHHHHTTST................TEEEEEEEEEEEESS-BBTTCEEEEEEEEE CS
        4HBT   1 gGvvhgGvylallDeaagaalrslggr................gilvvvvelsidflrpvrlgdeltvearvl 57 
                 +G++++ +y++++++a+  +++ ++                  gi++   +++id++ p++++d++tv+ r++
  EEA20141.1 137 MGHINNVAYVRYAETARVNLMHNYATNidpahqtewintvgnkGIGLILQSIKIDYKFPMTWPDKITVYHRLT 209
                 6*******************************************************************98877 PP

>> Acyl-ACP_TE  Acyl-ACP thioesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.1   3.2e-05      0.19     160     183 ..     128     150 ..     110     171 .. 0.81
   2 ?   -1.1   0.0      0.16   9.4e+02     195     217 ..     185     207 ..     181     238 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 3.2e-05
  Acyl-ACP_TE 160 kvrysDlDlnqHvNNvkYlewile 183
                   v + D+D  +H+NNv Y+ +  e
   EEA20141.1 128 DVVWGDMDSMGHINNVAYVRYA-E 150
                  57799*************9874.4 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.16
  Acyl-ACP_TE 195 lkkitlkYekevqlgdkveilte 217
                  l++i+++Y+ ++   dk+++  +
   EEA20141.1 185 LQSIKIDYKFPMTWPDKITVYHR 207
                  78899999988888888884433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (311 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       673  (0.037537); expected 358.6 (0.02)
Passed bias filter:                      441  (0.024597); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2212.71
//
Query:       EEA20142.1  [L=192]
Description: hypothetical protein PMAA_040030 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.9e-14   53.9   1.7    2.5e-14   53.6   1.7    1.0  1  Glyco_hydro_76  Glycosyl hydrolase family 76


Domain annotation for each model (and alignments):
>> Glyco_hydro_76  Glycosyl hydrolase family 76
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.6   1.7   1.4e-18   2.5e-14      87     220 ..      21     151 ..      11     154 .. 0.78

  Alignments for each domain:
  == domain 1  score: 53.6 bits;  conditional E-value: 1.4e-18
                     HHHHHHHHHHHHHHHH.......H--HHHHHHHHHHHHHHHHCB-SCSCCS-BBSEC..ESS--SEEEHHHHHHHHHHHHHHHHHH.--CH..HH CS
  Glyco_hydro_76  87 DDqafwglaamtaaernf.pep.tdepswLalAqavfntqasrwdeetcgGGlrWqiftwnsgydyknsisngplfqlaarLaryt.gnet..Yl 176
                     DD  + + a+ t+  +    +p + +p++L+lA +++n ++   d+  c GGl+W+        +y  si+n  +  laa La     +    Yl
      EEA20142.1  21 DDTTYNVNAICTWSVAIQeRAPhKMNPDYLNLAISIYNDISGGLDTP-C-GGLYWSK-----TETYIASIANELYIALAAGLANRVsSDLAgpYL 108
                     55555555555544332202335799********************8.4.99***75.....89*******************8774444456** PP

                     HHHHHHHHHHHHHSCSBTTTS-B-SEEETTTCCEE.EE---HHHH CS
  Glyco_hydro_76 177 ewAekvwdWvedvgliddedwlvyDgasvednctd.inklqwtYn 220
                     + A   wdW +++g++  +dwlv Dg+ ++++c+   nk+  t n
      EEA20142.1 109 DAAVTGWDWFVNIGVV-GDDWLVVDGV-DNNTCQPtGNKYSSTTN 151
                     ***************9.**********.66777542666666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (192 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       406  (0.0226449); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.25s 00:00:00.65 Elapsed: 00:00:00.43
# Mc/sec: 1337.54
//
Query:       EEA20143.1  [L=84]
Description: NADH-ubiquinone oxidoreductase complex 1/LYR family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.1e-08   33.6   0.0    4.9e-08   32.9   0.0    1.4  1  Complex1_LYR    Complex 1 protein (LYR family)
    1.8e-06   28.6   0.2    2.9e-06   27.9   0.2    1.4  1  Complex1_LYR_2  Complex1_LYR-like


Domain annotation for each model (and alignments):
>> Complex1_LYR  Complex 1 protein (LYR family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.9   0.0   5.5e-12   4.9e-08       1      55 [.       8      60 ..       8      64 .. 0.96

  Alignments for each domain:
  == domain 1  score: 32.9 bits;  conditional E-value: 5.5e-12
  Complex1_LYR  1 rqvLsLYRalLRearkfpdyntreyfrrriRdeFrknkhvtDpekieellkkgre 55
                  rqv++ Y+ lL  +r +p     +yfr +    F +  ++tDp++iee +k++++
    EEA20143.1  8 RQVIQVYKELLYLGREYPLGY--DYFRTKLHGAFAAKMNITDPKEIEEGIKRAEF 60
                  79*******************..***************************99985 PP

>> Complex1_LYR_2  Complex1_LYR-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.9   0.2   3.2e-10   2.9e-06       1      59 [.      10      67 ..      10      83 .. 0.86

  Alignments for each domain:
  == domain 1  score: 27.9 bits;  conditional E-value: 3.2e-10
  Complex1_LYR_2  1 vlsLYrrllrelrelppelrslgdayvraefrrhkhlknpeeialflknqreYaeller 59
                    v+++Y++ll + r ++p  + +++++++ +f ++ ++++p+ei + +k  + +++ +e 
      EEA20143.1 10 VIQVYKELLYLGR-EYPLGYDYFRTKLHGAFAAKMNITDPKEIEEGIKRAEFVKKEVEA 67
                    79**********9.99*****************88*********999999888887764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (84 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       394  (0.0219756); expected 358.6 (0.02)
Passed bias filter:                      225  (0.0125495); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.39u 0.26s 00:00:00.65 Elapsed: 00:00:00.43
# Mc/sec: 590.98
//
Query:       EEA20144.1  [L=448]
Description: SAM binding motif containing protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.7e-09   36.6   0.0    6.6e-08   33.2   0.0    2.3  1  Methyltransf_25  Methyltransferase domain
    8.8e-06   26.3   0.0    3.4e-05   24.4   0.0    2.0  1  Methyltransf_11  Methyltransferase domain
    0.00029   20.7   0.0    0.00094   19.0   0.0    1.8  2  Methyltransf_23  Methyltransferase domain
      0.003   17.3   0.0      0.008   16.0   0.0    1.7  1  Methyltransf_31  Methyltransferase domain
  ------ inclusion threshold ------
      0.015   14.7   0.0      0.079   12.3   0.0    1.9  1  Ubie_methyltran  ubiE/COQ5 methyltransferase family


Domain annotation for each model (and alignments):
>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.2   0.0   1.8e-11   6.6e-08       1      97 []     149     262 ..     149     262 .. 0.89

  Alignments for each domain:
  == domain 1  score: 33.2 bits;  conditional E-value: 1.8e-11
                      EEEET-TTSHHHHHHHCT..................S.TSSEEEEEESSHHHHHHHHHHHHHTTTTEEEEESBCCG..BSSSTTTEEEEEEEST CS
  Methyltransf_25   1 vLdlGcGtGrltlalakr..................l.gkakvtgvDiseemleaareraeeeglnvefvqgdaed..lpfedgsfDlvvssga 73 
                      +L+l+cG+G ++ a+++                     +  ++tg+Di + + +  r+ +     +++fv++d+++  lpf++++fD+v++  a
       EEA20144.1 149 ILELACGSGLWSHACHDYfleqdagdskspkgtlkdNkNTTSFTGLDIVSIAPDLRRKGV-----DWQFVRHDIRKppLPFPSDHFDFVFIKDA 237
                      89************9999999999999999987554234899******999999766655.....9********998899************99 PP

                      .GGGSSHHHHHHHHHHHHHHEEEEE CS
  Methyltransf_25  74 .lhhlsdedlekalkeiarvLkpgG 97 
                       l+    +++ ++l e  rvLk gG
       EEA20144.1 238 gLCQSATAQQIDLLGEPLRVLKRGG 262
                      999988889999************9 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4   0.0   9.4e-09   3.4e-05       2      95 ..     151     265 ..     150     266 .. 0.63

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 9.4e-09
                      EET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHHHHHCCHHT-.................EEEETTEECCC..TSS-TT-EEEEEEES.-CCC- CS
  Methyltransf_11   2 dvGcGtGrlaealakrg.arvvgvDlskemlklakekaseegl.................kvefvvadaek..lpfednsfDlvvsse.vlhhv 74 
                      +++cG+G+ + a+++++ ++  g   s++   + k+++++  +                   +fv+ d++k  lpf+++ fD+v+++   l+  
       EEA20144.1 151 ELACGSGLWSHACHDYFlEQDAGDSKSPK--GTLKDNKNTTSFtgldivsiapdlrrkgvDWQFVRHDIRKppLPFPSDHFDFVFIKDaGLCQS 242
                      66666666666666555322222222222..224444444433444444444444444444568******9889*************9534444 PP

                      ..CCHHHHHHHHHHHEEEEEEEE CS
  Methyltransf_11  75 ..edpekalkeiaRvLkpgGllv 95 
                        +++ ++l e  RvLk gG+l 
       EEA20144.1 243 atAQQIDLLGEPLRVLKRGGILE 265
                      678999**************985 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.0   0.0   2.6e-07   0.00094      18      86 ..     141     232 ..     123     292 .. 0.79
   2 ?   -1.9   0.0      0.72   2.6e+03       8      30 ..     418     441 ..     411     442 .. 0.71

  Alignments for each domain:
  == domain 1  score: 19.0 bits;  conditional E-value: 2.6e-07
  Methyltransf_23  18 pklraggrvLdiGcGtGillevlre.....................ngfsvtgvDlspeaveiaekakkaqkdqfdeqeaae.....pqgkfdl 85 
                       k+++++++L+++cG+G ++  + +                     n +s+tg D+ ++a ++++k   +q++ +d     +     p+++fd+
       EEA20144.1 141 LKDKRPKKILELACGSGLWSHACHDyfleqdagdskspkgtlkdnkNTTSFTGLDIVSIAPDLRRKGVDWQFVRHDIR---KpplpfPSDHFDF 231
                      4589***************998877566667777777766666665557**************986666666666444...3334559999999 PP

  Methyltransf_23  86 I 86 
                      +
       EEA20144.1 232 V 232
                      8 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.72
  Methyltransf_23   8 elsdklerllpkl.raggrvLdiG 30 
                      ++++ +  ll+k+  a+g++L++G
       EEA20144.1 418 WWAAMTTDLLQKNgLANGECLEVG 441
                      566666667766448999999999 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   2.2e-06     0.008       3     113 ..     145     270 ..     143     320 .. 0.77

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 2.2e-06
  Methyltransf_31   3 kglrvlDlGCGtGeltfelae..............elgpkae.........vvGiDiseeaielArenaqklgldnveFeqgdieelekl.led 72 
                      + +++l+l+CG+G  +++ ++                    +         ++G+Di    ++ A   ++++g+d  +F + di + + l +  
       EEA20144.1 145 RPKKILELACGSGLWSHACHDyfleqdagdskspkG-----TlkdnknttsFTGLDI----VSIAPD-LRRKGVD-WQFVRHDIRKPP-LpFPS 226
                      56899********99999999988876666544440.....2555555779*****9....555555.4568998.**********55.55999 PP

  Methyltransf_31  73 ekfDlilsnevl...naladpdkileeiervlkpggilliedpr 113
                      + fD+++ +++     a+a + + l+e  rvlk ggil + d +
       EEA20144.1 227 DHFDFVFIKDAGlcqSATAQQIDLLGEPLRVLKRGGILEVWDSD 270
                      ********988767889999999999***********9888777 PP

>> Ubie_methyltran  ubiE/COQ5 methyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   2.2e-05     0.079      44     158 ..     142     273 ..     136     280 .. 0.70

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 2.2e-05
                      -S--TTEEEEES-TT-HHHHHHHHHHHHHH..................EEEEEES-HHHHHHHHHHHHHHTSSTEEEEE--TTT..-TTS-T-E CS
  Ubie_methyltran  44 avkrgakvlDvagGtgDlafklsdsvgekg..................kvvvlDinenmLkvgekklkeegkinieflqanaee..Lpfeddsf 117
                       +kr++k+l++a+G+g ++ +  d   e+                     ++lD    +++++   l+++g+ + +f+  +  +  Lpf  d f
       EEA20144.1 142 KDKRPKKILELACGSGLWSHACHDYFLEQDagdskspkgtlkdnknttSFTGLD----IVSIA-PDLRRKGV-DWQFVRHDIRKppLPFPSDHF 229
                      579999************999888776655568889977777654333233333....33333.33555554.56777776654449******* PP

                      EEEEEE.S-GGG..-S-HHHHHHHHHHHEEEEEEEEEEEE---- CS
  Ubie_methyltran 118 Dvvtvs.fGlrn..vtDklkaLkeayrvlkpGGrlvvlefskve 158
                      D+v +   Gl    ++ +   L e  rvlk GG+l v +  +v 
       EEA20144.1 230 DFVFIKdAGLCQsaTAQQIDLLGEPLRVLKRGGILEVWDSDHVF 273
                      ***99537887611445556799************998877765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (448 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       368  (0.0205254); expected 358.6 (0.02)
Passed bias filter:                      267  (0.0148921); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.46
# Mc/sec: 2910.25
//
Query:       EEA20145.1  [L=685]
Description: transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.5e-20   71.6   0.0    2.3e-19   69.9   0.0    1.9  1  Exo_endo_phos  Endonuclease/Exonuclease/phosphatase family
    7.5e-13   48.5   1.9    1.5e-06   28.4   0.6    2.5  2  LRR_4          Leucine Rich repeats (2 copies)
    1.8e-12   46.8   7.3    6.4e-08   32.3   1.1    2.0  3  LRR_8          Leucine rich repeat
  ------ inclusion threshold ------
        4.3    8.3   4.4    1.7e+02    3.4   0.1    4.0  5  LRR_1          Leucine Rich Repeat


Domain annotation for each model (and alignments):
>> Exo_endo_phos  Endonuclease/Exonuclease/phosphatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.9   0.0   5.1e-23   2.3e-19       1     233 []     315     656 ..     315     656 .. 0.88

  Alignments for each domain:
  == domain 1  score: 69.9 bits;  conditional E-value: 5.1e-23
                    EEEEESTG...........CHHHHTHHHHHHHHHHHHHHCTTSEEEEEEEBSCTCHHHHHHHHHTTCEEEEECCH......ECSSSTTSSEEEEEE CS
                    xxxxxxxx...........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxx RF
  Exo_endo_phos   1 ltwNvngq...........aspalgssrrsdrladlltaydaDvlgLQEvdddelsriplllalggflgasstsp......tgggggggnggavls 79 
                    l++N++ +           +s al +  r d ++++++++daD+ +LQE+d + ++++   +++++ + + + ++      + +  ++ +g+a+++
     EEA20145.1 315 LSYNTLCDqsaspshygyvPSRALAWEFRRDLILNEIRSHDADIACLQEIDQGNYNEFFREQLAYNDYKGVYWPRgramgmHEEEAKTVDGCATFF 410
                    689999999999999999999*****************************************998888888888899999999999********** PP

                    CSTEEEEEEEEEEETSSSSGCEEEEEEEEEEEEEEECCCHHGHHHHHHHHHHHHHHHHHHHHHTTSEEEE.......................... CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......................... RF
  Exo_endo_phos  80 rfpltslfrrtfiefndlvaalrreplaakleqlniashrdhdlvrdlqllalllqvealnadrgapviv.......................... 149
                    + +   l   + i+f++  ++                 ++d  + r +q+ +    v   n+ +g ++iv                          
     EEA20145.1 411 KASKYILLDKQMINFGQTAVRRPDAK------------GQDDIYNRLWQKDHIAVVVFLENRMTGTRLIVvnahlywdpafkdvkliqtailmeei 494
                    ****9998888888777777777666............5667788888888888888888888888888899999999999999999999999999 PP

                    .....................................................EEE-SSSTSGGGBSCGHHHHHHCTTTH........H....... CS
                    .....................................................xxxxxxxxxxxxxxxxxxxxxxxxxxx........x....... RF
  Exo_endo_phos 150 .....................................................aGDfNarpsdddsrvlrtrglalapap........v....... 177
                                                                         +GDfN++p +  +++l+ +gl  a+                  
     EEA20145.1 495 tklsekyskfppctdktafrfseaedgareattpvepapsaeyssgdqiplliCGDFNSAPGEAAYNLLAHGGLTEAHPDlekrlygnLsrvgmth 590
                    99999999999999999999999999999999999999999999999999999*********************9999987777766505667888 PP

                    .....SSCESCETTTTTTTTTTTEB-BEEEEEEC.HHHCCEEEEEEECCHHEEC....TSSCSSSB CS
                    .....xxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxx....xxxxxxxx RF
  Exo_endo_phos 178 .....glyllgggptptyvtraggsrlDrilasp.alalfrsgvlppplalvrr....ealtlSDH 233
                          +y+  g+  +t+ t+ ++s lD+i++s+ al + +++   +++ l r     + + +SDH
     EEA20145.1 591 pfklkSAYSAIGELSFTNYTPDFNSILDYIWFSStALHVTGLLGEVDKEYLQRVpgfpNYHFPSDH 656
                    8899*****************************988888888888888777777***********9 PP

>> LRR_4  Leucine Rich repeats (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.4   0.6   3.4e-10   1.5e-06       3      42 ..     182     218 ..     181     220 .. 0.88
   2 !   18.7   0.0   3.9e-07    0.0018       1      36 [.     226     261 ..     226     268 .. 0.89

  Alignments for each domain:
  == domain 1  score: 28.4 bits;  conditional E-value: 3.4e-10
                 --EEE--SS---E-S-.HHH-TT--EEE-.-S-----GGGG CS
       LRR_4   3 LevLdLsnNqltdipl.leklpnLkeLdLsgNnlitdldeL 42 
                 L +L+LsnN+l+ +p+ +++l +L++Ld+s N     l+eL
  EEA20145.1 182 LNKLYLSNNKLKALPPaIGQLRSLTHLDVSAN----ELTEL 218
                 679*************7777*********999....76666 PP

  == domain 2  score: 18.7 bits;  conditional E-value: 3.9e-07
                 SS--EEE--SS---E-S-.HHH-TT--EEE-.-S--- CS
       LRR_4   1 pnLevLdLsnNqltdipl.leklpnLkeLdLsgNnli 36 
                 +nL++L+ ++N+++++p+ l+ l  L+ L + gN ++
  EEA20145.1 226 TNLRTLYAFDNHIRSLPFeLGYLYRLEMLGIYGN-PL 261
                 7*****************8778*********999.33 PP

>> LRR_8  Leucine rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.7   0.6   7.6e-10   3.4e-06       6      61 .]     162     215 ..     160     215 .. 0.90
   2 !   32.3   1.1   1.4e-11   6.4e-08       3      61 .]     182     238 ..     180     238 .. 0.97
   3 ?    3.0   0.1     0.019        84      24      61 .]     225     261 ..     222     261 .. 0.81

  Alignments for each domain:
  == domain 1  score: 26.7 bits;  conditional E-value: 7.6e-10
                 EE-TTS--SEE-TTSSTT-TT--EEE--SS---GGGGGGGTT--S-.EEE--SS-- CS
       LRR_8   6 LdLsnNrltslddeaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 
                 Ld ++  l +++   F+  + L+ L+LsnN+l+ l p a+ +L+sL++Ld+s N L
  EEA20145.1 162 LDFTSQGLRAISTALFN-YKFLNKLYLSNNKLKAL-PPAIGQLRSLTHLDVSANEL 215
                 66677889999999999.69***************.99****************87 PP

  == domain 2  score: 32.3 bits;  conditional E-value: 1.4e-11
                 -SEEE-TTS--SEE-TTSSTT-TT--EEE--SS---GGGGGGGTT--S-.EEE--SS-- CS
       LRR_8   3 LtsLdLsnNrltslddeaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 
                 L++L+LsnN+l++l++   + l++L++Ld s N+lt l p  +  L++Lr L+  +N++
  EEA20145.1 182 LNKLYLSNNKLKALPPAIGQ-LRSLTHLDVSANELTEL-PCEIGMLTNLRTLYAFDNHI 238
                 89**************9999.*****************.9*****************98 PP

  == domain 3  score: 3.0 bits;  conditional E-value: 0.019
                 -TT--EEE--SS---GGGGGGGTT--S-.EEE--SS-- CS
       LRR_8  24 lsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 
                 l+nL++L+  +N +++l p  +  L +L++L + gN+L
  EEA20145.1 225 LTNLRTLYAFDNHIRSL-PFELGYLYRLEMLGIYGNPL 261
                 67888888888888888.78888888999998888876 PP

>> LRR_1  Leucine Rich Repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0         4   1.8e+04       7      22 ..      55      80 ..      55      80 .. 0.65
   2 ?    3.4   0.1     0.038   1.7e+02       2      17 ..     182     197 ..     181     202 .. 0.75
   3 ?    3.1   0.0     0.049   2.2e+02       1      16 [.     204     219 ..     204     222 .. 0.84
   4 ?   -0.2   0.0      0.58   2.6e+03       1      16 [.     227     242 ..     227     246 .. 0.80
   5 ?   -3.5   0.0         4   1.8e+04       2      12 ..     251     261 ..     250     270 .. 0.76

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 4
       LRR_1  7 Lsnnpl..........lglppnsfqn 22
                Ls++p+          ++++p+++qn
  EEA20145.1 55 LSHQPNfpagalasttPHFTPSHIQN 80
                56777655666666667788888875 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.038
       LRR_1   2 LrhLdLsnnpllglpp 17 
                 L +L+Lsnn l  lpp
  EEA20145.1 182 LNKLYLSNNKLKALPP 197
                 668*******955554 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.049
       LRR_1   1 nLrhLdLsnnpllglp 16 
                 +L+hLd+s n l+ lp
  EEA20145.1 204 SLTHLDVSANELTELP 219
                 69********997665 PP

  == domain 4  score: -0.2 bits;  conditional E-value: 0.58
       LRR_1   1 nLrhLdLsnnpllglp 16 
                 nLr+L+  +n++ +lp
  EEA20145.1 227 NLRTLYAFDNHIRSLP 242
                 8*****9999885554 PP

  == domain 5  score: -3.5 bits;  conditional E-value: 4
       LRR_1   2 LrhLdLsnnpl 12 
                 L+ L + +npl
  EEA20145.1 251 LEMLGIYGNPL 261
                 77788899998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (685 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       574  (0.0320152); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.64u 0.30s 00:00:00.94 Elapsed: 00:00:00.47
# Mc/sec: 4347.16
//
Query:       EEA20146.1  [L=348]
Description: alpha/beta hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.7e-45  155.2   0.0    2.1e-45  154.9   0.0    1.1  1  Hydrolase_4      Serine aminopeptidase, S33
    3.3e-10   41.0   0.0    4.4e-10   40.5   0.0    1.1  1  Abhydrolase_6    Alpha/beta hydrolase family
    4.6e-08   33.0   0.1    1.2e-07   31.6   0.1    1.7  2  Abhydrolase_1    alpha/beta hydrolase fold
    0.00016   20.6   0.0    0.00037   19.5   0.0    1.5  2  Chlorophyllase2  Chlorophyllase enzyme
  ------ inclusion threshold ------
      0.011   15.3   0.0        2.9    7.3   0.0    2.2  2  Peptidase_S9     Prolyl oligopeptidase family
      0.034   13.8   0.0      0.063   12.9   0.0    1.5  1  Esterase         Putative esterase
      0.035   13.2   0.0      0.062   12.4   0.0    1.3  1  DUF1749          Protein of unknown function (DUF1749)
       0.13   12.1   0.0         50    3.6   0.0    3.1  3  Abhydrolase_2    Phospholipase/Carboxylesterase
       0.18   11.1   0.0       0.36   10.1   0.0    1.4  1  DUF915           Alpha/beta hydrolase of unknown function (DU


Domain annotation for each model (and alignments):
>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  154.9   0.0   1.1e-48   2.1e-45       2     239 .]      55     325 ..      54     325 .. 0.93

  Alignments for each domain:
  == domain 1  score: 154.9 bits;  conditional E-value: 1.1e-48
  Hydrolase_4   2 epkavvvlvHGlaehsgryaelaeaLaaqGfavyalDhrGhGrse....gkrghvpsfddyvdDlaafvekvk..eehpelplfllGhSmGGlially 93 
                   p+a++ + HG+ +h++ + e++ +La  Gf+v  +D+rG+Grs       rgh+ s++ +++Dl+ f++ +   ++++  plfl+GhSmGG+ +l y
   EEA20146.1  55 TPRAILAFYHGYSDHCNSFFEFFPNLASSGFEVRSVDQRGWGRSVinnrKLRGHFGSTTAVMADLHFFLQSLIpfTKESSVPLFLMGHSMGGMNVLYY 152
                  69**********************************************99*******************999965566666***************** PP

  Hydrolase_4  94 l.......lrypd..........kvaglilsaPalkikaklkappllklllkllgkllpklqvsnnlkadslsrdpevvaayeadplv..hgkitvrl 172
                  +       +   +          kvag+  +aP++ ++++ +++++++ + ++++ l+p++++ ++l+++++s++p+v++ +++d+ v  h++ t++ 
   EEA20146.1 153 AlnpespyH---HqqdstpttkvKVAGILSIAPLITVHPSSQPSKIVEYAGRIAKLLMPRMTMVQKLQPTWISKNPAVIDDLNNDKGVlfHNTGTLEG 247
                  *77666532...044689999888999999*********988*******************************************98778******** PP

  Hydrolase_4 173 llelldamkrleeraakit..........lPllllhGeaDkvvdpeasrelyerlgsk.dktlklypglyHellnEpd 239
                  l+++ld +++l+e  +k             Pl++ hG++D++++ + +++l+e l+   d t+k y+ + H+l+nEpd
   EEA20146.1 248 LAGMLDRGAWLNECYKKTIredyvyrgdvPPLWVGHGTDDRITWFDSTKKLVEGLHFLeDTTFKEYKDASHKLMNEPD 325
                  *************99988789*******778*************************988*****************97 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.5   0.0   2.2e-13   4.4e-10       5     217 ..      64     327 ..      59     330 .. 0.67

  Alignments for each domain:
  == domain 1  score: 40.5 bits;  conditional E-value: 2.2e-13
                    --GC......GCHHHHHHHHCCTCEEEEE--TTSTS-.........GGCS--HHH..CHHHHHHHCCTT......TTSEEEEEETCHHHHHHHHHH CS
  Abhydrolase_6   5 HGagss.assWlvapLaallaagvhvlapDlpGhGrs.........dpppldled..ladlaalldelaa....gggpvvlvGHSlGGalalaaap 84 
                    HG + +  s +   ++ +l+++g++v ++D +G Grs         +   ++ +    adl+ +l++l+     +  p +l+GHS+GG+ +l    
     EEA20146.1  64 HGYSDHcNSFFE--FFPNLASSGFEVRSVDQRGWGRSvinnrklrgH---FGSTTavMADLHFFLQSLIPftkeSSVPLFLMGHSMGGMNVLY--- 151
                    885544566666..88999****************776666554322...22222224999999999999998888888**********9999... PP

                    CC.....................EE.EEES-..----TTTS----TTHHHHHHTT-C.........CCCHCCH........S-HS...CCCCHHHC CS
  Abhydrolase_6  85 la...................lvvg.vlldppptalpagllaaalelllallallrl.........lawlsre........plpr...lfladeda 140
                    +a                    v+g + ++p  t+ p + ++ ++e++ +  +ll++         ++w s++           +   lf++    
     EEA20146.1 152 YAlnpespyhhqqdstpttkvKVAGiLSIAPLITVHPSSQPSKIVEYAGRIAKLLMPrmtmvqklqPTWISKNpaviddlnN--DkgvLFHN---- 241
                    888888999999*******987788888888667777777888888888777766655556666777888665555554331..12345555.... PP

                    CCCHCHCCCGHHHHCCHHC.....HTT.CCHHTT-TTGCEEEC..TT-C....HHHHCHHCCCH.STTEEETCE...SSS-HHHHSHHHH CS
  Abhydrolase_6 141 daawrarlarlaallaglg.....llp.aaawadlpvpllvlg..geDp....lvprllerlla.qagarlpvvlpgaGHlphleepdev 217
                     +   + la++++  a+l      + +    +++  +pl ++g  ++D+         l + l+ +++ ++ +++++a+H ++  epd v
     EEA20146.1 242 -TGTLEGLAGMLDRGAWLNecykkTIReDYVYRGDVPPL-WVGhgTDDRitwfDSTKKLVEGLHfLEDTTF-KEYKDASHKLMN-EPDGV 327
                    .77777777777777766654444333233555555555.5544366666654222334445556777777.99******6665.77766 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.6   0.1   6.3e-11   1.2e-07       5      93 ..      62     155 ..      59     193 .. 0.85
   2 ?   -2.2   0.0       1.3   2.6e+03     180     250 ..     251     318 ..     248     321 .. 0.66

  Alignments for each domain:
  == domain 1  score: 31.6 bits;  conditional E-value: 6.3e-11
                    EE-STTTCGGGGTTGHHHHHHHHTTSEEEEEEETTSTTSSSTTTGB.CHH.SHHHHHHHHHHHHHHC......TTSSEEEEEETHHHHHHHHHHHH CS
  Abhydrolase_1   5 ilhGlpgssdvwaerglapaLakdgfdvillDlrGvgySspapacinddy.gtasvaddldrildal......gddkltlvGhSmGGmialayaae 93 
                    + hG+ +  ++++e  ++p+La +gf+v  +D+rG g+S    ++   ++ +t +v +dl+++l++l         +l l+GhSmGGm +l+ya+ 
     EEA20146.1  62 FYHGYSDHCNSFFE--FFPNLASSGFEVRSVDQRGWGRSVINNRKLRGHFgSTTAVMADLHFFLQSLipftkeSSVPLFLMGHSMGGMNVLYYALN 155
                    67************..***********************8888887755535566888888888877333333346788***************86 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.3
                    HHHHHHHHHHHHHHHCCHHHHHHHHHCTHHHHSEEEEEEETTCSSSCH.HHHHHHHHC...HTSEEEEEEETCSS CS
  Abhydrolase_1 180 slatgalksieqwpttdsaklllrlrelknvlaptlvisgtsDplvpp.kaledlaql...lpkkrlvvisdagH 250
                    +l++ga+++  + +t  ++++++ +        p  v +gt+D+++ + ++  +l +    l + + + + da H
     EEA20146.1 251 MLDRGAWLNECYKKTIREDYVYRGDVP------PLWVGHGTDDRIT-WfDSTKKLVEGlhfLEDTTFKEYKDASH 318
                    677788888888888888888877776......7777777777766.4466666655556555566666666666 PP

>> Chlorophyllase2  Chlorophyllase enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0   1.8e-07   0.00037      18     161 ..      58     216 ..      51     235 .. 0.80
   2 ?   -2.8   0.0       1.2   2.3e+03      64      79 ..     330     345 ..     318     346 .. 0.72

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 1.8e-07
  Chlorophyllase2  18 pvllflhGylllnslYsqlLkhiashgfivvapqlyk.....vaeada.keiksaakvlnWlakgLesvlpeevepdlsklalsgHSrGgktaf 105
                      ++l f hGy+   + + + + ++as gf v ++         +++++      s+++v+  l+  L+s +p   e+ +  l l gHS Gg  ++
       EEA20146.1  58 AILAFYHGYSDHCNSFFEFFPNLASSGFEVRSVDQRGwgrsvINNRKLrGHFGSTTAVMADLHFFLQSLIPFTKESSV-PLFLMGHSMGGMNVL 150
                      6899******6666666899**********999544445554556666688899999999999999999996655554.588************ PP

  Chlorophyllase2 106 alalgkak...........tslkfsaligvdPvagaskskqtepkiLtyepesfnlkmpvlviGtgL 161
                        al+ ++           t++k++ ++ + P+  ++  +  ++ki++y  +  +l mp + +  +L
       EEA20146.1 151 YYALNPESpyhhqqdstptTKVKVAGILSIAPLITVH-PSSQPSKIVEYAGRIAKLLMPRMTMVQKL 216
                      ****988888878888776667***********9877.566789***************98776665 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1.2
  Chlorophyllase2  64 ksaakvlnWlakgLes 79 
                        ++ v++Wl+++L +
       EEA20146.1 330 AMTKDVTEWLEARLPK 345
                      567899****999875 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.0     0.004         8      62      83 ..     133     154 ..      72     171 .. 0.71
   2 ?    7.3   0.0    0.0014       2.9     142     207 ..     275     341 ..     254     345 .. 0.79

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.004
                   -GGGEEEEEETHHHHHHHHHHH CS
  Peptidase_S9  62 dserlaitGgSyGGyltgaaln 83 
                   +s  l+++G+S GG++++  + 
    EEA20146.1 133 SSVPLFLMGHSMGGMNVLYYAL 154
                   4556899*********998766 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0014
                   ---EEEEEEETT-SSS-THHHHHHHHHHH--S-SEEEEEETTS-SSTTSSHHHH..HHHHHHHHHHHH CS
  Peptidase_S9 142 aypplLlihGlaDdrvppaealklvaaLqkkgknvlllifpdegHgvgkprakv..eelarllaFlke 207
                     ppl + hG+ D  + + ++ klv+ L    +++ ++ ++d+ H + ++ + v  + +++++++l+ 
    EEA20146.1 275 DVPPLWVGHGTDDRITWFDSTKKLVEGLHFL-EDTTFKEYKDASHKLMNEPDGVgdAMTKDVTEWLEA 341
                   679999**********************953.456789999999977666665556677888888865 PP

>> Esterase  Putative esterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   3.2e-05     0.063     112     136 ..     129     156 ..     106     275 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 3.2e-05
                 EECCC...EEEEEETHHHHHHHHHHHCS CS
    Esterase 112 tapdg...ravaGqSmGGlgALilalkh 136
                 +++++     ++G+SmGG+  L++al+ 
  EEA20146.1 129 FTKESsvpLFLMGHSMGGMNVLYYALNP 156
                 44444445779**************984 PP

>> DUF1749  Protein of unknown function (DUF1749)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   3.1e-05     0.062     106     128 ..     136     158 ..     116     184 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 3.1e-05
     DUF1749 106 kvvlmGHstGsqdvlyYltssne 128
                  + lmGHs G  +vlyY+ ++++
  EEA20146.1 136 PLFLMGHSMGGMNVLYYALNPES 158
                 5689*************998754 PP

>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0      0.17   3.5e+02       9      34 ..      52      77 ..      49      85 .. 0.83
   2 ?    3.1   0.0     0.036        71     108     130 ..     138     160 ..     127     162 .. 0.86
   3 ?    3.6   0.0     0.025        50     159     203 ..     279     322 ..     271     327 .. 0.88

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.17
                   -SS---EEEEEE--TT--SHHHHHHH CS
  Abhydrolase_2  9 pkdkaqavviflHGlGdsghawaeaa 34
                   p+  ++a++ f HG+ d  ++++e +
     EEA20146.1 52 PEGTPRAILAFYHGYSDHCNSFFEFF 77
                   667789999********999998765 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.036
                    EEEEETHHHHHHHHHHHT-SS-- CS
  Abhydrolase_2 108 iigGFSqGaalalylaltlpkkl 130
                    +++G S+G++ +ly al  + ++
     EEA20146.1 138 FLMGHSMGGMNVLYYALNPESPY 160
                    799***********999877665 PP

  == domain 3  score: 3.6 bits;  conditional E-value: 0.025
                    EEEEEETT-SSS-HHHHHHHHHHHHTTS-GEEEEEETT--SS--H CS
  Abhydrolase_2 159 ilqiHgeeDpvvplalgkaakevlkkllkkvelksyeglaHside 203
                       +Hg++D +  +   k++ e l  +l++ ++k y++ +H+ ++
     EEA20146.1 279 LWVGHGTDDRITWFDSTKKLVEGLH-FLEDTTFKEYKDASHKLMN 322
                    5678***************999986.7778***********9876 PP

>> DUF915  Alpha/beta hydrolase of unknown function (DUF915)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   0.00018      0.36     107     123 ..     139     155 ..     135     173 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00018
      DUF915 107 avGhSmGglaltsYlee 123
                 ++GhSmGg+++++Y+ +
  EEA20146.1 139 LMGHSMGGMNVLYYALN 155
                 68************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (348 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       272  (0.015171); expected 358.6 (0.02)
Passed bias filter:                      264  (0.0147247); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.68u 0.36s 00:00:01.04 Elapsed: 00:00:00.61
# Mc/sec: 1726.53
//
Query:       EEA20147.1  [L=448]
Description: tRNA (adenine-N(1)-)-methyltransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.7e-06   26.5   0.0     0.0091   15.7   0.0    2.4  2  GCD14            tRNA methyltransferase complex GCD14 subunit
    0.00053   19.8   0.3     0.0014   18.4   0.1    1.8  2  GCD14_N          tRNA methyltransferase complex GCD14 subunit
  ------ inclusion threshold ------
      0.018   16.0   0.1       0.14   13.2   0.1    2.1  1  Methyltransf_24  Methyltransferase domain
      0.028   15.1   0.1        2.5    8.9   0.0    2.5  2  Methyltransf_25  Methyltransferase domain
      0.074   12.7   0.0       0.12   11.9   0.0    1.3  1  Methyltransf_28  Putative S-adenosyl-L-methionine-dependent m


Domain annotation for each model (and alignments):
>> GCD14  tRNA methyltransferase complex GCD14 subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.3   0.0   0.00046       1.6      40      63 ..     143     166 ..      97     170 .. 0.67
   2 !   15.7   0.0   2.5e-06    0.0091     118     181 ..     297     366 ..     285     430 .. 0.62

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00046
       GCD14  40 pGsvvvesGtGsgslshaiartva 63 
                 p   ++e+GtG gsl+  +ar+++
  EEA20147.1 143 PRLEILEAGTGHGSLTLHLARAIQ 166
                 334689****************97 PP

  == domain 2  score: 15.7 bits;  conditional E-value: 2.5e-06
       GCD14 118 fLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLrelg..fteietlevll.....rtyevrk 181
                  LD+P+  + i h++ al +++g l  f P i q+ ++++ +++ +  f+  +++e+ +     r ++vr 
  EEA20147.1 297 ILDMPSAHKRISHVVPAL-RRDGLLVVFMPSITQIGECVQLIQKEKlpFVMERVVELGMgisggRLWDVRM 366
                 69****************.8899*****************9987652255445555543222335555543 PP

>> GCD14_N  tRNA methyltransferase complex GCD14 subunit N-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.1     4e-07    0.0014       3      45 ..      39      80 ..      38      81 .. 0.88
   2 ?   -3.2   0.0       2.2   7.8e+03       6      13 ..     330     337 ..     329     340 .. 0.81

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 4e-07
     GCD14_N  3 pfraGdrVqLtDaKgrkhtitLepGgefhthrGaieHDdlIGr 45
                +fr+Gdr      +  ++t  L+ G+++   rG+++H+d+IG+
  EEA20147.1 39 VFREGDRAI-IQGRIPHITKPLKHGNRTEVARGYLNHNDIIGS 80
                589999975.55678899************************7 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.2
     GCD14_N   6 aGdrVqLt 13 
                  G+ VqL 
  EEA20147.1 330 IGECVQLI 337
                 69****97 PP

>> Methyltransf_24  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.1   3.8e-05      0.14       1     102 [.     148     321 ..     148     322 .. 0.57

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 3.8e-05
  Methyltransf_24   1 vEiGvysGvstlwllralrrnga..........................................grlvavdhdpg.................. 34 
                      +E G+ +G  tl+l+ra++++++                                                                       
       EEA20147.1 148 LEAGTGHGSLTLHLARAIQAANTnppaipqksqvrileerpvrsyeedaekleaqaanvedrtdaI---------Vqkawdqwrsqrravintv 232
                      799********************9******966666666554444444444444444444333330.........0222222322333333333 PP

  Methyltransf_24  35 .........aeeaaalare.......aglddrvrlikadseeala.sla..agsiDllfiDgghaa.........eavledleallprlapggv 100
                               ae       +         ++ +v+++++  e+ ++ +l+  +++  l+  Dg ++           ++ + + ++ p l+++g+
       EEA20147.1 233 dvspkfsahAE-------QvvrgfrrGIYAGNVDFHVGAVEDWIKdQLQrrRSPKGLFTGDGTAEPflsyaildmPSAHKRISHVVPALRRDGL 319
                      33222422222.......1222344477777788888888777663444665666777777776655655666655666667777777777777 PP

  Methyltransf_24 101 vl 102
                      ++
       EEA20147.1 320 LV 321
                      76 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.0   0.00068       2.5       1      26 [.     147     167 ..     147     230 .. 0.70
   2 ?    3.9   0.0     0.025        91      22      58 ..     227     268 ..     212     275 .. 0.80

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00068
                      EEEET-TTSHHHHHHHCTSTSSEEEE CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlgkakvtg 26 
                      +L++G+G+G ltl+la++++     +
       EEA20147.1 147 ILEAGTGHGSLTLHLARAIQ-----A 167
                      8***************9963.....3 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.025
                      SEEEEEESSHHHHHHHHHHHHH..TTT...TEEEEESBCCGB CS
  Methyltransf_25  22 akvtgvDiseemleaareraee..egl...nvefvqgdaedl 58 
                      a +  vD+s+++ ++a++ ++   +g+   nv+f++g +ed+
       EEA20147.1 227 AVINTVDVSPKFSAHAEQVVRGfrRGIyagNVDFHVGAVEDW 268
                      456679***********9997665555889********9997 PP

>> Methyltransf_28  Putative S-adenosyl-L-methionine-dependent methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   3.4e-05      0.12      16      92 ..     141     221 ..     132     241 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 3.4e-05
  Methyltransf_28  16 pskklrliElGpGkGtLmadvLrtlr..kflpefyea.leyhlvEaSpqlr.erQknrLkekakevkk...estvkslgvkveW 92 
                      + ++l+++E G G+G L  ++ r+++  +++p+ + +  ++ ++E  p    e+ +++L+ +a++v+     +  k++++   W
       EEA20147.1 141 QTPRLEILEAGTGHGSLTLHLARAIQaaNTNPPAIPQkSQVRILEERPVRSyEEDAEKLEAQAANVEDrtdAIVQKAWDQ---W 221
                      34569****************99999885556555555*******99976537788999998888877665455555555...5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (448 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       542  (0.0302304); expected 358.6 (0.02)
Passed bias filter:                      450  (0.025099); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.52u 0.30s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 3076.51
//
Query:       EEA20148.1  [L=805]
Description: phosphoesterase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-19   71.0   0.0    3.5e-19   69.9   0.0    1.6  1  HAD              haloacid dehalogenase-like hydrolase
    2.4e-16   60.9   0.2    4.6e-16   59.9   0.2    1.5  1  Metallophos      Calcineurin-like phosphoesterase
    0.00021   21.5   0.0     0.0023   18.1   0.0    2.2  1  Metallophos_2    Calcineurin-like phosphoesterase superfamily
  ------ inclusion threshold ------
       0.12   11.8   0.0         10    5.4   0.0    2.4  2  Put_Phosphatase  Putative Phosphatase


Domain annotation for each model (and alignments):
>> HAD  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.9   0.0   7.9e-23   3.5e-19       2     187 ..      21     202 ..      20     203 .. 0.84

  Alignments for each domain:
  == domain 1  score: 69.9 bits;  conditional E-value: 7.9e-23
         HAD   2 lfDfDgTLldgdslelllrfllrrgaprlwralreklllalfrellrldraglaelleallaglseelaaelerfvaevirpklldpgalellaahraa 100
                 + DfDgT++ +ds+++l++  l+      ++  r +  +++  ++  ++r++++ +l++   g+  e+++ l++ +      k ldp ++e++ +++++
  EEA20148.1  21 FTDFDGTITLKDSNDFLTD-NLGY-----GQVKRKQRNEDV-LTGRASFRDAFRDMLDSVKPGFG-ECIQILKENM------K-LDPYFVEFYYWAKEN 104
                 89*****************.7776.....444444445555.77778888999999999999995.5667777777......4.88************* PP

         HAD 101 GdrvvvvSgglrplvepll.aelg......adevlatelevdd..rltge....lglegkpvrgegkvaalrewlaaegegidleevvayGDspsDlpl 186
                 ++++vvvS+g+ p++  l  ++lg      + +++a+++e++d  +++      +++++++ +g++k  +++   +a+  +++++++ + GD++sDl +
  EEA20148.1 105 NVPIVVVSSGMAPIISGLFeELLGhkpdpkHLAIVANDVESRDgkDINSPggwqIKYHDDSHFGHDKSLEIKP--YAALPADKRPTLLYAGDGVSDLSA 201
                 *******************78999**99777778***********55555568899*****************..555556667778999*******99 PP

         HAD 187 l 187
                 +
  EEA20148.1 202 A 202
                 7 PP

>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.9   0.2     1e-19   4.6e-16       1     203 [.     477     726 ..     477     727 .. 0.67

  Alignments for each domain:
  == domain 1  score: 59.9 bits;  conditional E-value: 1e-19
                  EEEEEEESBTB.................TTCCTHHHHHHHHHHHHHHHTTESEEEEESTSSSSS...HHHHHHHHHHHHHHHHTSEEEEEC-TTS... CS
  Metallophos   1 lrilvigDlHl.................algggqlddllkllddllreekpdlvllaGDlvdrg...dlekellellaalvkypipvylllGNHe... 75 
                  ++i++ +DlHl                  + ++  +++l+++++ll+eekpdlv++ GD v++    d ++++ +++++lv+++ip++++ GNH+   
   EEA20148.1 477 FKIMQAADLHLttgtgacrdpvpeekvpGEKCEADPRTLDFVEKLLDEEKPDLVVFSGDEVNGEtskDAQSAVFKFVKPLVDRKIPYAAIFGNHDdeg 574
                  79**************************99999999999************************889999999***********************443 PP

                  CHHHHHHHHHHHHHHHHHHHEHH.......HCEEETSEEEE..EETTE...EEEEEEESECEEETHHHHHHHHHHHSCHHHHCC.HHHHHH...HHHH CS
  Metallophos  76 gfeeellnkygylgifsepwrsd.......aevfnnlplas..lgsgs...lkvlllhGgspellvsldklgslnleleapepg.dewlkd...lekr 157
                  +     l++ +  ++  e+ +s         + ++n+ + +    s++   l+++ll+ +      s ++ ++  +  +++ p   +w+k    + k+
   EEA20148.1 575 N-----LSRKQLMALLEELPYSVstagpddIDGVGNYIVEVmgRSSTHhsaLTLYLLDTH------SYSPDERHFRGYDWIKPSqIKWFKSmsqSLKK 661
                  1.....333333333322221111222222222222222221133333555445555555......55555555555555555559999999764444 PP

                  TTCSEEEEEE.....SSESS.......CSSSCSCCHHHHH..............HHHHHTTESEEEEESSSS CS
  Metallophos 158 ekadwvivlg.....Hsply.......rgsgylfgdeale..............dllkkygvdlvisGHtHv 203
                  ++ ++ + +      H+pl+       +        +                 d l + ++  v +GH+Hv
   EEA20148.1 662 KHSQYSHMHMdmafiHIPLPeyredtnT-------WKGNWleaptapafnsgfmDALVEQNILFVSCGHDHV 726
                  4444444444566668888866444442.......33333446666689999999999999**********7 PP

>> Metallophos_2  Calcineurin-like phosphoesterase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   5.1e-07    0.0023      21     130 ..     520     727 ..     478     762 .. 0.57

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 5.1e-07
  Metallophos_2  21 ealkevgvdaiihaGD......leeeep.......evleellela.pvlaVrGNnD........................................ 62 
                    + l+e+++d+++++GD                   ++++ l +++ p  a++GN+D                                        
     EEA20148.1 520 KLLDEEKPDLVVFSGDevngetS----KdaqsavfKFVKPLVDRKiPYAAIFGNHDdegnlsrkqlmalleelpysvstagpddidgvgnyivevm 611
                    34567889********5444430....133333336778888777***********7777777777777776666666666666666655555555 PP

  Metallophos_2  63 ............................eev.veedvlreaaelgtdlp.eeaelelagekvlliHgdpl....................gvkdal 108
                                                +++ ++    + ++ ++++l+ ++ + +   +++++iH   +                    + + ++
     EEA20148.1 612 grssthhsaltlylldthsyspderhfrGYDwIKPSQIKWFKSMSQSLKkKHSQYSHMHMDMAFIHIPLPeyredtntwkgnwleaptapAFNSGF 707
                    555555555555555555555554444422233334444444444444334444444445566666653366666666666655554333333333 PP

  Metallophos_2 109 aellkeaeegsd..vvvcGHtHvp 130
                    +++l e  +  +  +v cGH Hv 
     EEA20148.1 708 MDALVE--Q--NilFVSCGHDHVN 727
                    333333..2..2236666666666 PP

>> Put_Phosphatase  Putative Phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   0.0    0.0023        10       3      35 ..      20      52 ..      18     116 .. 0.72
   2 ?    3.6   0.0    0.0081        36     171     213 ..     188     227 ..     178     239 .. 0.83

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.0023
  Put_Phosphatase  3 vvfDFDktiidedsdnwvvdelpatelfeelre 35
                        DFD ti  +ds++ ++d l+  ++ ++ r+
       EEA20148.1 20 FFTDFDGTITLKDSNDFLTDNLGYGQVKRKQRN 52
                     456*******************99887665544 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.0081
  Put_Phosphatase 171 rliYvGDganDlCpvlklrekDvampRkgfpleklisenksll 213
                       l+Y GDg  Dl +    +e+D+ +++kg++l +  +++ + +
       EEA20148.1 188 TLLYAGDGVSDLSAA---AETDLLFAKKGHDLIRYCEREGMPF 227
                      689********9876...689*********9999888877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (805 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       505  (0.0281667); expected 358.6 (0.02)
Passed bias filter:                      484  (0.0269954); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.71u 0.31s 00:00:01.02 Elapsed: 00:00:00.47
# Mc/sec: 5107.05
//
Query:       EEA20149.1  [L=405]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.1e-05   26.1   0.0       0.16   12.7   0.0    2.7  3  NAD_binding_1  Oxidoreductase NAD-binding domain
    2.9e-05   24.2   0.0    7.8e-05   22.8   0.0    1.7  1  NAD_binding_6  Ferric reductase NAD binding domain


Domain annotation for each model (and alignments):
>> NAD_binding_1  Oxidoreductase NAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       1.6   1.4e+04      38      61 ..      44      67 ..      38      82 .. 0.57
   2 !   12.7   0.0   1.7e-05      0.16       1      23 [.     226     248 ..     226     271 .. 0.87
   3 !   10.7   0.0   7.3e-05      0.66      88     105 ..     367     384 ..     319     388 .. 0.81

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 1.6
                   CGSTTHHHHHHHHHHCTTEEEEEE CS
  NAD_binding_1 38 edllyreeleelakklpgrlkvva 61
                   +++ +  e++++a+ ++++l  v+
     EEA20149.1 44 RKHSIPHETRTAAEPRQNKLYTVR 67
                   555555666666665555544443 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 1.7e-05
                    EEEEGGGGHHHHHHHHHHHHHCT CS
  NAD_binding_1   1 miagGtGiaPvrsvlraileeak 23 
                    ++agG+Gi P+ s+l +++ee++
     EEA20149.1 226 FVAGGVGINPLISILSHLTEEQT 248
                    79*****************9943 PP

  == domain 3  score: 10.7 bits;  conditional E-value: 7.3e-05
                    HSSTTEEEEEECSHHHHH CS
  NAD_binding_1  88 lkkeethvyvCGppgMik 105
                      +e+t +y+CGpp+M +
     EEA20149.1 367 PRQEDTVYYICGPPPMTD 384
                    4699************86 PP

>> NAD_binding_6  Ferric reductase NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8   0.0   8.7e-09   7.8e-05       3     153 ..     223     388 ..     221     391 .. 0.76

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 8.7e-09
                    xxxxxxxxxxxxxxxxxxxxxxxxxx.........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxx........ RF
  NAD_binding_6   3 nvllvagGiGitpfisilkdllkksk.........kealktkkikliwvvressslewfkdvLneleeekse.gnieihiYlTseyea........ 80 
                     +++vagG+Gi p+isil +l +++           ++ +  +i +  ++    s    ++ L+++  +++  + ++ +  +T++ ++        
     EEA20149.1 223 KIVFVAGGVGINPLISILSHLTEEQTanptiplpeRSPNNPLHIRFLYSTQIPASSAPDEKTLDQILFLSRLrNIVQRTRTVTKQPSKirleldlf 318
                    689********************9999*******98888888999999999999998889999999999988444455555666655576666666 PP

                    .xxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  NAD_binding_6  81 .edasdqlissiegenseslk..qgvdavsgtrnvkihfgRPnlkevlkdiaskhknssvgvfvCGppklvkevkk 153
                     ++ s++   ++ g+ +++ k  ++v+  s++   ++h  R n +++  +      ++ +  ++CGpp +++e+ +
     EEA20149.1 319 lTNISSSAAAAQAGKVLNEVKdgSNVNDSSPLI--QVHSRRINKDDLDAKP----RQEDTVYYICGPPPMTDEFVQ 388
                    555555555555555555555777777777776..9999999988765555....888888999******999765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (405 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       348  (0.0194099); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2625.42
//
Query:       EEA20150.1  [L=327]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.4e-05   23.5   4.5    6.5e-05   23.0   4.5    1.3  1  MARVEL    Membrane-associating domain
    0.00014   21.6   1.5     0.0052   16.4   0.0    2.5  2  SUR7      SUR7/PalI family
  ------ inclusion threshold ------
      0.071   12.1   0.0      0.095   11.6   0.0    1.1  1  Amidase   Amidase
        0.4   10.3   3.5       0.51   10.0   0.0    2.3  2  NEMP      NEMP family


Domain annotation for each model (and alignments):
>> MARVEL  Membrane-associating domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.0   4.5   1.5e-08   6.5e-05      29     144 .]      37     188 ..      12     188 .. 0.78

  Alignments for each domain:
  == domain 1  score: 23.0 bits;  conditional E-value: 1.5e-08
      MARVEL  29 a...............................kldqllgspssalnfavfvavfsflyalfllvlylfknsaftsilwplidlivdalaallwlvafia 96 
                 +                               +++  + ++s   n+ + ++v+s +++l+ + +      ++ +++ p +  +v++++++l+++a+++
  EEA20150.1  37 HdtyttklwqdganngfnsapnqivyaltngrTYNVPIVWSSVVYNYDLIIGVLSTFIILAKVPV------HVLRFFYPPVSAVVHGILCILYIIAACF 129
                 4555666666666666666666666666666657778899999999999********99999999......889************************* PP

      MARVEL  97 laaglrdisca..........fe.snqysasltvrcgqaqaavafgflavllfaasavl 144
                  a   ++ s +           + s+ ys s+ + c+qa+a  a++++av+l+++ ++l
  EEA20150.1 130 QAGSDTTDSRHpqhgppwyitKScSVAYSRSNIGYCQQAKALFALTVVAVVLYFVETIL 188
                 *98777756668888877754228899999999**********************9886 PP

>> SUR7  SUR7/PalI family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   1.7     0.025   1.1e+02      97     168 ..      56     129 ..      33     136 .. 0.67
   2 !   16.4   0.0   1.2e-06    0.0052     108     142 ..     164     198 ..     151     220 .. 0.86

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.025
        SUR7  97 lPsnlrktlsk...lnnltkalfilhiialvlsfislvvgllaicvspdnsrllsflnlllsvlsflatllaall 168
                  P+++ ++l+    +n  + ++ +++   l++ ++s +++l  + v+      +  + +++  +  ++ ++aa+ 
  EEA20150.1  56 APNQIVYALTNgrtYNVPIVWSSVVYNYDLIIGVLSTFIILAKVPVHVLRFF-YPPVSAVVHGILCILYIIAACF 129
                 6777777776666688889999999988888888888888887753444444.6667777777777777777765 PP

  == domain 2  score: 16.4 bits;  conditional E-value: 1.2e-06
        SUR7 108 lnnltkalfilhiialvlsfislvvgllaicvspd 142
                 + +  kalf+l ++a+vl f++ ++++++++ s++
  EEA20150.1 164 YCQQAKALFALTVVAVVLYFVETILAIMSCFASQE 198
                 467789*************************6655 PP

>> Amidase  Amidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   2.1e-05     0.095     333     435 ..     184     283 ..     148     285 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 2.1e-05
                 HHHHHHHHHHHCSCCCCCCCHHHHHHHHHHHHHHHHHHCCC.BSEEEEESSSSS--BCCCCCHHHCSHHHHHGCCTTT...HHHHHTT--EEEEECCCC CS
     Amidase 333 vkrrielgnyalsaeasskyylkaqkvrrllrrefakafee.lDvllsPtaptpaprlgekdktidsytvlynlldftavvvpvnlaglpalsvpagks 430
                 v+  +  ++   s+e +++++++ q+++r+ +++ ++a++e  D++ sP++p pa++  + ++ + s++ +y     t   ++++ a++++l+ p+  s
  EEA20150.1 184 VETILAIMSCFASQE-EKDAWQRRQEEKREEKEAEDRALREyEDIINSPAFPPPAMPGAAYTP-GLSPQPMYSPFHQT--HFFQSQAQYQSLNDPSPSS 278
                 555566666666666.58889999999999***********77******99999999666654.58999999988888..7888888999998888888 PP

                 T.TEC CS
     Amidase 431 edglP 435
                  ++lP
  EEA20150.1 279 SSDLP 283
                 77877 PP

>> NEMP  NEMP family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   1.8       0.2   8.9e+02      23      54 ..      93     126 ..      76     135 .. 0.70
   2 ?   10.0   0.0   0.00011      0.51     150     224 ..     171     235 ..     162     261 .. 0.63

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.2
        NEMP  23 LfllAptlSrsvlFYY..ssgmalGillsllivl 54 
                 +++lA+   + + F+Y  +s+++ Gil+ l i++
  EEA20150.1  93 FIILAKVPVHVLRFFYppVSAVVHGILCILYIIA 126
                 4457777778888888767899999966665554 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00011
        NEMP 150 elalaalilllllknlpelvlsllkrklrkrklfplkkpkrrllteeEyreqgeketkkaleelreycrspecss 224
                  +al++++++l          + ++++l  +++f ++++k    +++E ++++++  ++al+e  + ++sp +++
  EEA20150.1 171 LFALTVVAVVL----------YFVETILAIMSCFASQEEKDAWQRRQEEKREEKEAEDRALREYEDIINSPAFPP 235
                 33333333333..........3333333333445555555555555555555556679*************9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (327 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1323  (0.0737911); expected 358.6 (0.02)
Passed bias filter:                      840  (0.0468515); expected 358.6 (0.02)
Passed Vit filter:                        83  (0.00462937); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.50
# Mc/sec: 1978.61
//
Query:       EEA20151.1  [L=670]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.5e-26   91.7   3.9    1.2e-24   86.8   0.1    3.2  3  T5orf172     T5orf172 domain
    3.1e-18   66.2   0.9    6.4e-16   58.8   0.3    2.7  2  MUG113       Meiotically up-regulated gene 113
  ------ inclusion threshold ------
      0.058   11.5   0.1      0.085   10.9   0.1    1.1  1  DNA_pol_phi  DNA polymerase phi


Domain annotation for each model (and alignments):
>> T5orf172  T5orf172 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0      0.65   3.9e+03      28      77 ..      89     132 ..      79     149 .. 0.64
   2 !    4.6   0.1    0.0081        48      44      80 ..     299     337 ..     279     348 .. 0.72
   3 !   86.8   0.1   2.1e-28   1.2e-24       1     102 [.     494     597 ..     494     602 .. 0.85

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.65
    T5orf172  28 rRlkelskyptkppselevvaekevrkvpnahrvErlihkeLadrryrvk 77 
                   l+  + +p+k+ +e++     ++ ++p ++r  +++ +++++r++ ++
  EEA20151.1  89 DELQGTK-DPSKQDEEFD-----THSPSPASRRTRSAARHKFQARNLSLE 132
                 4444444.4555544443.....456788888888888888888776665 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.0081
    T5orf172  44 levvae..kevrkvpnahrvErlihkeLadrryrvkcdc 80 
                  ++ ++  +++ +++  +r+E+ ih+ La+  +  +c++
  EEA20151.1 299 QKSREAslSKITPIEIRERLENDIHHCLASTTQGRRCKR 337
                 33322233778999999*************777666554 PP

  == domain 3  score: 86.8 bits;  conditional E-value: 2.1e-28
    T5orf172   1 gyvYiltnessegetillKIGrtsn.vqrRlkelskyptkppselevvae...kevrkvpnahrvErlihkeLad.rryrvkcdcgk.ehrEwFevsle 93 
                 g++Y+++++s++g+   lKIG+t+  +q+R+k++s++++k+++ +++ ++   +e  +v + +rvE+l+h eL++ rr++++c+ +  +hrEwFevsl+
  EEA20151.1 494 GIIYVYWQPSNFGH---LKIGCTTLdLQKRMKAWSNQCNKSMELYFP-NPndaQELVPVSHIYRVEKLVHMELKNlRRIEQSCPGCRqNHREWFEVSLD 588
                 79************...*******99*********766665555554.445778889******************8889999999999*******9977 PP

    T5orf172  94 evdevvrri 102
                  + evvr++
  EEA20151.1 589 LAVEVVRKW 597
                 777777666 PP

>> MUG113  Meiotically up-regulated gene 113
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.0   0.0    0.0064        38      35      54 ..     313     336 ..     283     366 .. 0.74
   2 !   58.8   0.3   1.1e-19   6.4e-16       1      77 []     508     597 ..     508     597 .. 0.96

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0064
      MUG113  35 pnahrlErllhleLkd....krlr 54 
                 +   rlE+++h+ L++    +r++
  EEA20151.1 313 EIRERLENDIHHCLASttqgRRCK 336
                 3679***********965444444 PP

  == domain 2  score: 58.8 bits;  conditional E-value: 1.1e-19
      MUG113   1 lKIGrTn.nverRlnelnrqcpskltllryyppss......pnahrlErllhleLkd.krlrdekcdc.....EwFevpaeslkavirkw 77 
                 lKIG+T+ ++++R++ +++qc   ++l+ + p +        +  r+E+l+h eLk+ +r+ + + +c     EwFev+++ + +v+rkw
  EEA20151.1 508 LKIGCTTlDLQKRMKAWSNQCNKSMELYFPNPNDAqelvpvSHIYRVEKLVHMELKNlRRIEQSCPGCrqnhrEWFEVSLDLAVEVVRKW 597
                 7********************9999999999988899**999***************9999999999999*******************9 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.1   1.4e-05     0.085     408     488 ..     276     357 ..     256     385 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 1.4e-05
  DNA_pol_phi 408 kewvqeilkflavlgffka.kssieetekkpspalsestrelcrerlfslLselssqsgsekdgeswlykllellktleksk 488
                  ++++q++l+ l  ++f  +  ++++  e++ s  +  ++re++++ + ++L++ +++   + ++es  +++++ l+++ k+k
   EEA20151.1 276 DDTIQHVLSLLSAQAFSASsPKEQKSREASLSKITPIEIRERLENDIHHCLASTTQGRRCKRTSESDSSQIIRSLDSITKIK 357
                  478999************9555556666666666666********************6666666666666666666666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (670 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       675  (0.0376485); expected 358.6 (0.02)
Passed bias filter:                      458  (0.0255452); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.45
# Mc/sec: 4495.33
//
Query:       EEA20152.1  [L=1173]
Description: copper-transporting ATPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.3e-51  172.7   1.1    5.3e-51  172.7   1.1    2.3  2  E1-E2_ATPase     E1-E2 ATPase
    3.8e-48  161.8   4.3    7.3e-12   45.6   0.1    4.9  5  HMA              Heavy-metal-associated domain
    3.5e-36  125.5   0.6    8.7e-36  124.2   0.6    1.7  1  Hydrolase        haloacid dehalogenase-like hydrolase
    5.9e-07   29.5   0.3    6.3e-05   22.8   0.1    2.3  2  Hydrolase_3      haloacid dehalogenase-like hydrolase
  ------ inclusion threshold ------
      0.035   14.0   3.2       0.38   10.6   0.1    3.1  3  Transketolase_C  Transketolase, C-terminal domain
      0.041   14.3   0.1       0.13   12.6   0.1    1.8  1  HAD              haloacid dehalogenase-like hydrolase
      0.076   13.3   1.4        8.1    6.8   0.0    4.3  6  EccE             Putative type VII ESX secretion system trans
      0.095   12.6   0.2       0.45   10.4   0.2    2.2  1  PASTA            PASTA domain
      0.099   12.5   1.6        4.4    7.1   0.3    2.8  3  CDCA             Cadmium carbonic anhydrase repeat
       0.25   11.4   2.6        5.9    7.0   0.2    2.6  2  MpPF26           M penetrans paralogue family 26


Domain annotation for each model (and alignments):
>> E1-E2_ATPase  E1-E2 ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.3       1.9   3.4e+03     116     150 ..     444     478 ..     434     490 .. 0.55
   2 !  172.7   1.1     3e-54   5.3e-51      12     180 ..     548     732 ..     539     733 .. 0.94

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 1.9
                   HHHHHHHHHHHHHHHHHHHHS-STTTSSTTHHHHH CS
  E1-E2_ATPase 116 dklgkvlvpvvlliallvflialllgkslaeallr 150
                   d l+   + ++++++++++l+a++  +  + + ++
    EEA20152.1 444 DVLVMLGTSAAFFFSVFTMLVAIFGSQHNRPSTVF 478
                   44555555666666666666666655555533333 PP

  == domain 2  score: 172.7 bits;  conditional E-value: 3e-54
                   TTS-EEEEGGG--TTSEEEEETT-B--SEEEEEEE-SEEE-TTTS---S-EE-G-TTEE-TT-EEEE-EEEEEEEE-TTTSTTTTTSTTS------- CS
  E1-E2_ATPase  12 dgteeeidakelvpGDivllkagdrvpaDgrivegsaevdesaLTGEslpvekekgdmvfsGtvvvsgeakavVtatgedtelgkiarlveeakskk 108
                    g ++ ++++ l++GD+vll++gd+v+aDg++++g + vdes++TGE++p+ k+kgd v++Gtv+ +g+++++Vt+ g+dt+l++i++lv++a+ ++
    EEA20152.1 548 QGGLKAVPTELLQVGDVVLLRPGDKVSADGVVIQGASHVDESMITGEARPINKKKGDAVIAGTVNGAGSLEFKVTRAGSDTQLSQIVKLVQNAQTSR 644
                   578899******************************************************************************************* PP

                   -HHHHHHHHHHHHHHHHHHHHHHHHHHS-STTTSSTT................HHHHHHHHHHHHHS-TTHHHHHHHHHHHHHHHHHH CS
  E1-E2_ATPase 109 tplqkkldklgkvlvpvvlliallvflialllgksla................eallralallvaaiPcaLplavplalalgarrlak 180
                   +p+q+++d +++++vp+++l++l++f+++++l + l                   l   ++++v a+PcaL+l +p+a+++g++  a+
    EEA20152.1 645 APIQRMADIVAGYFVPIIILLGLTTFVAWMILSHVLPhppkifnkpenggkimVCLKLCISVIVFACPCALGLSTPTAVMVGTGVGAE 732
                   *******************************777776777888999999988555555************************998776 PP

>> HMA  Heavy-metal-associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.6   0.1   4.1e-15   7.3e-12       1      62 []      24      85 ..      24      85 .. 0.97
   2 !   44.9   0.2   6.5e-15   1.2e-11       1      61 [.     111     171 ..     111     172 .. 0.95
   3 !   38.2   0.1   7.9e-13   1.4e-09       1      62 []     199     260 ..     199     260 .. 0.97
   4 !   31.0   0.0   1.4e-10   2.6e-07       6      61 ..     286     341 ..     281     342 .. 0.95
   5 ?   -2.6   0.0       4.4   7.8e+03      50      62 .]     918     930 ..     904     930 .. 0.75

  Alignments for each domain:
  == domain 1  score: 45.6 bits;  conditional E-value: 4.1e-15
         HMA  1 tvrvsgmhCagCaakvekvLselpgVesvkvdlatktvtVegdaestklrkiieaiekagyk 62
                tv+v+gm+C++C ++ve +++ ++g  +v+v+l+ ++++V +d+++++++k+ e ie+ g++
  EEA20152.1 24 TVKVDGMTCGACTSAVENAFKDVQGAGEVSVSLVMGRAVVHHDPTALPPSKVAELIEDRGFD 85
                799******************************************************98875 PP

  == domain 2  score: 44.9 bits;  conditional E-value: 6.5e-15
         HMA   1 tvrvsgmhCagCaakvekvLselpgVesvkvdlatktvtVegdaestklrkiieaiekagy 61 
                 t++++gm+C++C ++ve  L+ + g++sv+v+l + +++Ve+d + ++ ++i   ie+ g+
  EEA20152.1 111 TIAIEGMTCGACTSAVEGGLKDVAGIYSVNVSLLSERAVVEHDSTVVTASQIADIIEDRGF 171
                 689*******************************************999***999998665 PP

  == domain 3  score: 38.2 bits;  conditional E-value: 7.9e-13
         HMA   1 tvrvsgmhCagCaakvekvLselpgVesvkvdlatktvtVegdaestklrkiieaiekagyk 62 
                 tv+++gm+C++C ++v+ ++  ++g  + +++l + ++++++d+e ++ +ki   ie+ g++
  EEA20152.1 199 TVAIEGMTCGACTSSVTNAFNDVEGLVQFDISLLAERAVIVHDPEILSSEKIASMIEDVGFD 260
                 799*******************************************999********99986 PP

  == domain 4  score: 31.0 bits;  conditional E-value: 1.4e-10
         HMA   6 gmhCagCaakvekvLselpgVesvkvdlatktvtVegdaestklrkiieaiekagy 61 
                 g+  a++a++ e+vL+  pg++s+++d  t+++t+ ++++ + +r ++eaie+agy
  EEA20152.1 286 GLNGAASASSLEEVLKQKPGISSISIDILTSRATIIHNPTTIGIRSVVEAIEAAGY 341
                 7778999************************************************9 PP

  == domain 5  score: -2.6 bits;  conditional E-value: 4.4
         HMA  50 rkiieaiekagyk 62 
                  ++++a++k+gy+
  EEA20152.1 918 VAVVAALHKMGYH 930
                 56999******97 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  124.2   0.6   4.8e-39   8.7e-36       1     209 [.     749     995 ..     749     995 .. 0.85

  Alignments for each domain:
  == domain 1  score: 124.2 bits;  conditional E-value: 4.8e-39
                 SSEEEEESBTTTBCHHHHHHH.....HHHHHCHHHHHHHHHH......HHCHHHHHHHHHHHHH.........HHHHHHHHHETTTE............ CS
                 xxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxx.........xxxxxxxxxxxxxx............ RF
   Hydrolase   1 iktvvfDkdGTLttgepsved.....vivsaalalaaaletg......sehpigkalvaaakar.........sgaltgfatfigrg............ 67 
                 ++ +vfDk+GTLt+g++sv +     ++ s+++ ++   +++      sehp ++a+vaaak++          g +  f + +g+g            
  EEA20152.1 749 VNHIVFDKTGTLTEGKMSVAEtklepTWMSNDWRRKLWWQIVglaetnSEHPVARAIVAAAKQEmglmsddslNGTVGTFDATAGKGisatvepmssve 847
                 689***************999666665555577777777777788888*********************9988888899999***************** PP

                 ....HHHHTHHHHHHHH......HCHHHHHHHHHHHHHHCHHHHHH.............TTHHHHHHHHHHTHHBHTTHHHHHHHHHHTTEEEEEEESS CS
                 ....xxxxxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxx.............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase  68 ....ayaigkpewltal......dippdlgaaigsaqsqgrtvall.............qaralavftiadplkvkpeaaeavasLkaagievvlltgd 143
                      +++g++ +l+++        ++ +++  +++ +       +             ++++ + + + d   +k  a+ +va+L+++g+ v ++tgd
  EEA20152.1 848 rtrySVLMGNVIFLRSNgvnvpeSAESTVNDSASTEPK-------KddfagftqihvaiDGHYTGTISLRDA--LKSSAVAVVAALHKMGYHVSIVTGD 937
                 *****************875554222222222222222.......122335557777889************..************************* PP

                 EHHHHHHHHHHTTGGGESEEEEHHCES..STTTSHHHHHHHHHHHTSTGGGEEEEESSHHHHHHHHHT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase 144 npetaeraanqlGddyfdaviasdiet..vakpspegkvaaireLqgkpeevamVGDgvnDaaalaaA 209
                     a ++a+ lG          + +t   a++ p+gk+++i+ +q+ + +vamVGDg+nD++ala A
  EEA20152.1 938 TYPAALAVARALG----------IPKTsvKAGVVPSGKKEIIESYQAAGDKVAMVGDGINDSPALATA 995
                 *************..........555588*******************99***************976 PP

>> Hydrolase_3  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0     0.015        26      17      55 ..     914     952 ..     905     959 .. 0.87
   2 !   22.8   0.1   3.5e-08   6.3e-05     193     247 ..     966    1020 ..     962    1026 .. 0.92

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.015
                  -HHHHHHHHHHHHTTSEEEEE-SS-HHHHHHHHHHCCCC CS
  Hydrolase_3  17 sektkeaikklkekgikvviATGRslravlpvleelgld 55 
                  + +++++++ l++ g++v i TG  + a+l v+++lg+ 
   EEA20152.1 914 KSSAVAVVAALHKMGYHVSIVTGDTYPAALAVARALGIP 952
                  5677889999**************************986 PP

  == domain 2  score: 22.8 bits;  conditional E-value: 3.5e-08
                   HHHHHHCT--GGGEEEEESSGGGHHHHHHSSEEEEETTS-HHHHHHSSEEE--GG CS
  Hydrolase_3  193 kklakelnisleeviafGDgeNDieMLeaaglgvAmgnaseevkkaAdyvtksnn 247 
                   k++++ ++   ++v+ +GDg ND + L  a +g+A++++++ + +aAd v    +
   EEA20152.1  966 KEIIESYQAAGDKVAMVGDGINDSPALATALVGIALASGTDVAMEAADVVLMRSD 1020
                   7899********************************************9986655 PP

>> Transketolase_C  Transketolase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.0     0.062   1.1e+02      26      55 ..      74     103 ..      72     141 .. 0.76
   2 ?   10.6   0.1   0.00021      0.38      19      89 ..     154     224 ..     146     265 .. 0.85
   3 ?   -3.9   0.1       6.7   1.2e+04       9      28 ..     928     946 ..     917     950 .. 0.49

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.062
                      HHHHHHHTTTTCEEEEE-SEEESHHHHHHH CS
  Transketolase_C  26 eAaeeLekegisaeVvdlrtvkplDketil 55 
                      ++ae +e++g +aeV++    +  Dk++ +
       EEA20152.1  74 KVAELIEDRGFDAEVLSTDMPQTTDKKDHA 103
                      79****************999999999876 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00021
                      THHHHHHHHHHHHHTTTTCEEEEE-SEEESHHHHHHHHHHHHHSEEEEEEEEESTTSHHHHHHHHHHH.CCC CS
  Transketolase_C  19 smveealeAaeeLekegisaeVvdlrtvkplDketilesvkktgrlvvveeavkrgGigsevaaalae.eaf 89 
                      s+v +a ++a+ +e++g +a+V+d  + +p D    ++  +     v +e +++ g++ s v++a+++ e++
       EEA20152.1 154 STVVTASQIADIIEDRGFGASVLDTKSAEPSDSPSSNNTTQMMSTTVAIE-GMTCGACTSSVTNAFNDvEGL 224
                      78999***************************999997777776666665.577799999999999985554 PP

  == domain 3  score: -3.9 bits;  conditional E-value: 6.7
                      TSSEEEEEETTHHHHHHHHH CS
  Transketolase_C   9 gkdvtlvayGsmveealeAa 28 
                      g +v +v +G + + al++a
       EEA20152.1 928 GYHVSIV-TGDTYPAALAVA 946
                      4444444.355555555555 PP

>> HAD  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.1   7.3e-05      0.13      88     187 ..     915     992 ..     888     993 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 7.3e-05
         HAD  88 pgalellaahraaGdrvvvvSgglrplvepllaelgadevlatelevddrltgelglegkpvrgegkvaalrewlaaegegidleevvayGDspsDlpl 186
                   a++++aa ++ G++v +v+g   p + +++++lg    +         ++++       v  +gk   +++      + ++ ++v  +GD+++D p+
  EEA20152.1 915 SSAVAVVAALHKMGYHVSIVTGDTYPAALAVARALG----IPKT-----SVKAG-------VVPSGKKEIIES------YQAAGDKVAMVGDGINDSPA 991
                 5789999*999*************************....5551.....33333.......333334445555......55556668888888888888 PP

         HAD 187 l 187
                 l
  EEA20152.1 992 L 992
                 6 PP

>> EccE  Putative type VII ESX secretion system translocon, EccE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0       2.3   4.1e+03      42      72 ..      74     104 ..      72     115 .. 0.76
   2 ?    1.1   0.0      0.29   5.1e+02      35      62 ..     154     181 ..     139     204 .. 0.79
   3 ?   -2.2   0.0       3.1   5.5e+03      40      58 ..     247     265 ..     244     269 .. 0.88
   4 ?   -2.5   0.0       3.6   6.5e+03      41      76 ..     330     365 ..     322     370 .. 0.83
   5 ?   -2.4   0.0       3.5   6.3e+03      78      92 ..     518     541 ..     500     544 .. 0.65
   6 ?    6.8   0.0    0.0045       8.1      21      70 ..     898     947 ..     893     967 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 2.3
        EccE  42 RlakaLreqGirarvleaeeldaalaalavg 72 
                 ++a+ ++++G++a vl+ +  ++ ++  ++g
  EEA20152.1  74 KVAELIEDRGFDAEVLSTDMPQTTDKKDHAG 104
                 68889999*******9987666666655555 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.29
        EccE  35 aaaaaarRlakaLreqGirarvleaeel 62 
                   +++a+++a+ ++++G+ a+vl+ +  
  EEA20152.1 154 STVVTASQIADIIEDRGFGASVLDTKSA 181
                 45678899**************998765 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 3.1
        EccE  40 arRlakaLreqGirarvle 58 
                 ++++a+ +++ G++arvl+
  EEA20152.1 247 SEKIASMIEDVGFDARVLS 265
                 7899*************97 PP

  == domain 4  score: -2.5 bits;  conditional E-value: 3.6
        EccE  41 rRlakaLreqGirarvleaeeldaalaalavglaaa 76 
                 r +++a++ +G++a + + e+ +a l+ la  ++ +
  EEA20152.1 330 RSVVEAIEAAGYNALLSDFEDNNAQLESLAKTKEIQ 365
                 678999999999999999999999999998877655 PP

  == domain 5  score: -2.4 bits;  conditional E-value: 3.5
        EccE  78 a.........dvreewrtirtrdg 92 
                 +         +++eew++ +t+ g
  EEA20152.1 518 TiyedpiaaeKAAEEWNEKNTGAG 541
                 255555566678999*99998876 PP

  == domain 6  score: 6.8 bits;  conditional E-value: 0.0045
        EccE  21 alsaRgggtegaaraaaaaarRlakaLreqGirarvleaeeldaalaala 70 
                 a++ +  gt +++ a+ + a  +++aL++ G+ +++++ + ++aala++ 
  EEA20152.1 898 AIDGHYTGTISLRDALKSSAVAVVAALHKMGYHVSIVTGDTYPAALAVAR 947
                 5666667999***********************************99865 PP

>> PASTA  PASTA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.2   0.00025      0.45       6      52 ..     934     980 ..     930     987 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00025
                 TTTSBHHHHHHHHHHTT--CCCEEEECTCCGTTB..EEEECS-TTSEEC CS
       PASTA   6 vtGmsvdeAkatLkalGlkiktveetsddvpeGt..VisQsPeaGtevs 52 
                 vtG ++  A a ++alG++ + v+     vp+G+  +i+++ +aG +v 
  EEA20152.1 934 VTGDTYPAALAVARALGIPKTSVKA--GVVPSGKkeIIESYQAAGDKVA 980
                 89****************7666666..566666666**********994 PP

>> CDCA  Cadmium carbonic anhydrase repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0      0.91   1.6e+03      71      90 ..      30      49 ..      18      91 .. 0.76
   2 ?    7.1   0.3    0.0024       4.4      48     110 ..      94     170 ..      85     183 .. 0.83
   3 ?    2.7   0.0     0.057     1e+02      71     107 ..     205     255 ..     191     267 .. 0.71

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.91
        CDCA 71 lgCgflklwltgkladlasv 90
                + Cg++   +++ ++d++  
  EEA20152.1 30 MTCGACTSAVENAFKDVQGA 49
                89*****9999999999865 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0024
        CDCA  48 qeitqevkekghvpsvhgddhgelgCgflklwltgkladlasv..............rlakpgfsaeegaaiveaag 110
                  ++t++  ++g++ sv       + Cg++   ++g l+d+a +              + +    +a + a i+e  g
  EEA20152.1  94 PQTTDKKDHAGAQSSVTTIAIEGMTCGACTSAVEGGLKDVAGIysvnvsllseravvEHDSTVVTASQIADIIEDRG 170
                 567777788999****9999889******************998899999999988888888888999999988873 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.057
        CDCA  71 lgCgflklwltgkladlasv..............rlakpgfsaeegaaive 107
                 + Cg++   +t+ ++d++ +                ++  +s e+ a+++e
  EEA20152.1 205 MTCGACTSSVTNAFNDVEGLvqfdisllaeraviVHDPEILSSEKIASMIE 255
                 89***************9886666666666666544444445555555555 PP

>> MpPF26  M penetrans paralogue family 26
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.2    0.0033       5.9       4      62 ..     432     492 ..     429     494 .. 0.72
   2 ?    3.6   0.2     0.039        69      25     116 ..     662     713 ..     635     716 .. 0.58

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0033
      MpPF26   4 llkkikklsltiiilyllatv.lllvsllayiv.llskskllskeyeeesslleaelligv 62 
                 ++k++k  s t+ +l++l t  ++++s+ +++v +   + +  + + + s++l++ + +g 
  EEA20152.1 432 SFKSLKHRSPTMDVLVMLGTSaAFFFSVFTMLVaIFGSQHNRPSTVFDTSTMLITFITLGR 492
                 699*********9999988875566666655550555666777888888888888776665 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.039
      MpPF26  25 lllvsllayivllskskllskeyeeesslleaelligvllillidifyivnfileiiLiiKvselkkkhpefkkvklhtvLliigifilpif 116
                 ++l++l+++++ ++ s +l +  ++++++ ++                                         k+ ++ +L i +i++  ++
  EEA20152.1 662 IILLGLTTFVAWMILSHVLPHPPKIFNKPENG----------------------------------------GKIMVCLKLCISVIVFACPC 713
                 34444444455555555555555555555554........................................55555555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1173 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       630  (0.0351386); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.85u 0.30s 00:00:01.14 Elapsed: 00:00:00.50
# Mc/sec: 7119.85
//
Query:       EEA20153.1  [L=376]
Description: DNA repair protein Rad1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-88  295.4   0.0    3.6e-88  295.2   0.0    1.0  1  Rad1      Repair protein Rad1/Rec1/Rad17


Domain annotation for each model (and alignments):
>> Rad1  Repair protein Rad1/Rec1/Rad17
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  295.2   0.0     2e-92   3.6e-88       1     275 []       4     328 ..       4     328 .. 0.95

  Alignments for each domain:
  == domain 1  score: 295.2 bits;  conditional E-value: 2e-92
        Rad1   1 vfsAtlsnvseLatlLksiafkdkalvqissdGlkfivednrvlqaqafldkalFtsYtfenaqdd.......edeedeeedsvsfevsLsallecLni 92 
                 +fsA+++++ +L+tlL++i+f++ka +qi++dG++f+ve++rv+q+ +fld+alFt+Ytf++++ +       +dee+ e+ +++f +sL+alle+L+i
  EEA20153.1   4 IFSAVSNDAYHLYTLLRCIGFAEKARIQITPDGIRFSVEESRVMQGLVFLDRALFTTYTFNAPPLQnrngnalDDEESAEDIYPQFLISLTALLETLQI 102
                 6***********************************************************99999899*****9************************* PP

        Rad1  93 fgkndssskessssraskv.........asssakatscklsYkgeGsPLvliLeeagvtttcelsTyepe........edldleldrqevvlkvilkse 174
                 fg  d+s+++  +++              +++++ ++c l Y+ +GsPL ++L+e+gvtttcel+Tye +         ++d++l+r+++++k+i++s+
  EEA20153.1 103 FGIGDASQSSFLPNGS--LqntpsgaftSPALLLGRTCALRYSSPGSPLCITLSESGVTTTCELTTYESDdpsfgsagGEVDIPLQRDAIIMKIIMRSA 199
                 ******9875544443..2458899*9999***************************************9999999999******************** PP

        Rad1 175 lLhsalteLdat.skklkilassekkapvfalsak.gelgssevefpneks........................vlekfevs...sl.sessessYkf 243
                 +L++a++eLdat +++l+i+ass+ +ap+++ls++ g++++s+v+f+ +k+                        v+e+f+v+   s+ s ++e+ Y+f
  EEA20153.1 200 WLYNAINELDATnPTTLTISASSK-TAPFLSLSGSgGPFSESSVKFSTDKEkvdseanyknlqddgvkrarlapaVTETFQVNppsSMgSLVKEN-YRF 296
                 ***********************6.99********9*************************************************8885555555.*** PP

        Rad1 244 allkkaakalalssKvslrmdeaGlLslqfmi 275
                 al++ka++a+a++sKvs+r d +G+Lslqfmi
  EEA20153.1 297 ALIRKASRAMAAASKVSIRGDIQGVLSLQFMI 328
                 *******************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (376 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       287  (0.0160076); expected 358.6 (0.02)
Passed bias filter:                      276  (0.0153941); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2684.29
//
Query:       EEA20154.1  [L=76]
Description: hypothetical protein PMAA_040150 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.2e-21   74.7   8.7    5.9e-21   74.5   8.7    1.0  1  Ost5      Oligosaccharyltransferase subunit 5
  ------ inclusion threshold ------
      0.021   14.8   2.7      0.025   14.5   2.7    1.1  1  DUF485    Protein of unknown function, DUF485
        3.2    7.0   4.8        3.5    6.8   4.8    1.1  1  CorA      CorA-like Mg2+ transporter protein


Domain annotation for each model (and alignments):
>> Ost5  Oligosaccharyltransferase subunit 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.5   8.7   9.8e-25   5.9e-21       2      73 .]      13      76 .]      12      76 .] 0.98

  Alignments for each domain:
  == domain 1  score: 74.5 bits;  conditional E-value: 9.8e-25
        Ost5  2 pfsppvppslqptlafvllligllltalfflyevtstkkkrslvkelllalvASlflGfGvvflllavGVYV 73
                p++p+v ++ q+ ++f ll+i+lllt+lf+l+        rs+++ +ll+l+ASl++GfG+vf+++avGVYV
  EEA20154.1 13 PYYPIVAKDNQFAVGFALLFIALLLTGLFGLN--------RSFLNIPLLGLPASLAFGFGAVFMICAVGVYV 76
                9****************************999........9******************************9 PP

>> DUF485  Protein of unknown function, DUF485
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   2.7   4.2e-06     0.025       9      73 ..      17      76 .]      10      76 .] 0.79

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 4.2e-06
      DUF485  9 LvrkrrrfafpltaiflvvYfgfvllvafapdllatkvgegnitvglllgllqivltflltglYv 73
                +v+k ++fa+ ++++f++  +++  l+++++++l+ +++ g ++  l++g++ +++ + ++g+Yv
  EEA20154.1 17 IVAKDNQFAVGFALLFIA--LLLTGLFGLNRSFLNIPLL-G-LPASLAFGFGAVFM-ICAVGVYV 76
                678889999998888887..578899*************.8.88889999887554.45567776 PP

>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   4.8   0.00059       3.5     241     285 ..      28      74 ..      22      76 .] 0.75

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.00059
        CorA 241 taif.lPlTlitGiyGmN..fkglPelewsygypfvlllglmallail 285
                  a++ +   l+tG++G N  f ++P l+ +   +f +  ++m++++++
  EEA20154.1  28 FALLfIA-LLLTGLFGLNrsFLNIPLLGLPASLAFGFGAVFMICAVGV 74 
                 4555477.89********666679988888877888888888887775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (76 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       569  (0.0317363); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.38u 0.27s 00:00:00.65 Elapsed: 00:00:00.44
# Mc/sec: 522.43
//
Query:       EEA20155.1  [L=439]
Description: histone acetyltransferase (Gcn5), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.9e-24   83.5   0.7    1.8e-23   82.4   0.7    1.6  1  Bromodomain      Bromodomain
    3.5e-08   33.7   0.0    6.9e-08   32.7   0.0    1.5  1  Acetyltransf_1   Acetyltransferase (GNAT) family
      1e-06   28.7   0.0      2e-06   27.8   0.0    1.5  1  Acetyltransf_10  Acetyltransferase (GNAT) domain
    0.00048   20.5   0.1    0.00088   19.7   0.1    1.4  1  Acetyltransf_7   Acetyltransferase (GNAT) domain


Domain annotation for each model (and alignments):
>> Bromodomain  Bromodomain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.4   0.7   4.1e-27   1.8e-23       3      84 .]     333     414 ..     331     414 .. 0.97

  Alignments for each domain:
  == domain 1  score: 82.4 bits;  conditional E-value: 4.1e-27
                  HHHHHBHTTTCGGGGCSTT-GCCSTTHHHH.SS---HHHHHHHHHTT--SSHHHHHHHHHHHHHHHHHHSHTTSHHHHHHHH CS
  Bromodomain   3 kilsellehklaepFlepvdpeefpdyyavikkPldLstIkkklesnkYksladfeadlkllfsNarkyngegsviyelaek 84 
                  ++l+++ +h++a pF +pv+++e+pdyy+vik+P+dLst+++k e+  Y +++df  d+ l+f+N+rkyn+e+++++++a+k
   EEA20155.1 333 HLLNDMQNHSAAWPFVQPVNRDEVPDYYEVIKEPMDLSTMEEKHEKDLYPTPQDFIRDAMLIFDNCRKYNNETTPYAKSANK 414
                  6899***************************************************************************985 PP

>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.7   0.0   1.5e-11   6.9e-08      39     117 .]     149     223 ..     117     223 .. 0.83

  Alignments for each domain:
  == domain 1  score: 32.7 bits;  conditional E-value: 1.5e-11
                     EETTEEEEEEEEEEEETTSTTEEEEEEEEESGGGTTSSHHHHHHHHHHHHHHHT.TESEE.EEEEETTEHHHHHHHHHTTE CS
  Acetyltransf_1  39 eedgeliGfisllkipdekggvayieslaVspeyrgkGlGsaLlealeeraree.gikki.vlaveedndaairlYeklGF 117
                     ++  e++G i++++     ++ a+i ++a+s++ + kG+G +L+ +l ++++    +  + +l + +dn  ai++++k GF
      EEA20155.1 149 KHPLEVVGGITYRPFRG--RKFAEIVFCAISSDQQVKGYGAHLMSHLKDYVKATsDV--MhFL-TYADN-YAIGYFKKQGF 223
                     444579*******9999..9**********************************666..5356.66777.******88**9 PP

>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0   4.4e-10     2e-06      40     109 ..     152     226 ..     121     239 .. 0.81

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 4.4e-10
  Acetyltransf_10  40 gkivGvielrdgs.....hisllfVdpeyrgqGigkaLleaveeeaekdgikl.eltvnaspyavpfYeklGFkav 109
                       ++vG i++r  +     +i  ++++++++ +G+g+ L+ ++++++ k+ + + ++   a++ya+++++k+GF++ 
       EEA20155.1 152 LEVVGGITYRPFRgrkfaEIVFCAISSDQQVKGYGAHLMSHLKDYV-KATSDVmHFLTYADNYAIGYFKKQGFTKE 226
                      5677888664333456789999***********************9.6667778*******************875 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.1     2e-07   0.00088      12      75 ..     152     224 ..     136     225 .. 0.72

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 2e-07
                     TEEEEEEEEEEES....TCTEEEEE-GGGTTSSHHHHHHHH....TTSEEE.....EE.EEEETHHHHHHHHHHTTEE CS
  Acetyltransf_7  12 gkivGfialslld....aeitrlaVdpeyrgkGiGraLlea....aekgii.....le.qlelnaekaikfYeklGFe 75 
                      ++vG i + +      aei + a++ + + kG+G  L+ +    +    +     ++  ++ ++ +ai++++k GF+
      EEA20155.1 152 LEVVGGITYRPFRgrkfAEIVFCAISSDQQVKGYGAHLMSHlkdyV----KatsdvMHfLTYADN-YAIGYFKKQGFT 224
                     467888887777788777888899****************844331....122332343334444.9**********8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (439 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       585  (0.0326287); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 3053.40
//
Query:       EEA20156.1  [L=436]
Description: histone acetyltransferase (Gcn5), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.8e-24   83.6   0.7    1.8e-23   82.4   0.7    1.6  1  Bromodomain      Bromodomain
    3.5e-08   33.7   0.0    6.8e-08   32.8   0.0    1.5  1  Acetyltransf_1   Acetyltransferase (GNAT) family
      1e-06   28.7   0.0      2e-06   27.8   0.0    1.5  1  Acetyltransf_10  Acetyltransferase (GNAT) domain
    0.00047   20.5   0.1    0.00087   19.7   0.1    1.4  1  Acetyltransf_7   Acetyltransferase (GNAT) domain


Domain annotation for each model (and alignments):
>> Bromodomain  Bromodomain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.4   0.7     4e-27   1.8e-23       3      84 .]     333     414 ..     331     414 .. 0.97

  Alignments for each domain:
  == domain 1  score: 82.4 bits;  conditional E-value: 4e-27
                  HHHHHBHTTTCGGGGCSTT-GCCSTTHHHH.SS---HHHHHHHHHTT--SSHHHHHHHHHHHHHHHHHHSHTTSHHHHHHHH CS
  Bromodomain   3 kilsellehklaepFlepvdpeefpdyyavikkPldLstIkkklesnkYksladfeadlkllfsNarkyngegsviyelaek 84 
                  ++l+++ +h++a pF +pv+++e+pdyy+vik+P+dLst+++k e+  Y +++df  d+ l+f+N+rkyn+e+++++++a+k
   EEA20156.1 333 HLLNDMQNHSAAWPFVQPVNRDEVPDYYEVIKEPMDLSTMEEKHEKDLYPTPQDFIRDAMLIFDNCRKYNNETTPYAKSANK 414
                  6899***************************************************************************985 PP

>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.8   0.0   1.5e-11   6.8e-08      39     117 .]     149     223 ..     117     223 .. 0.83

  Alignments for each domain:
  == domain 1  score: 32.8 bits;  conditional E-value: 1.5e-11
                     EETTEEEEEEEEEEEETTSTTEEEEEEEEESGGGTTSSHHHHHHHHHHHHHHHT.TESEE.EEEEETTEHHHHHHHHHTTE CS
  Acetyltransf_1  39 eedgeliGfisllkipdekggvayieslaVspeyrgkGlGsaLlealeeraree.gikki.vlaveedndaairlYeklGF 117
                     ++  e++G i++++     ++ a+i ++a+s++ + kG+G +L+ +l ++++    +  + +l + +dn  ai++++k GF
      EEA20156.1 149 KHPLEVVGGITYRPFRG--RKFAEIVFCAISSDQQVKGYGAHLMSHLKDYVKATsDV--MhFL-TYADN-YAIGYFKKQGF 223
                     444579*******9999..9**********************************666..5356.66777.******88**9 PP

>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0   4.4e-10     2e-06      40     109 ..     152     226 ..     121     239 .. 0.81

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 4.4e-10
  Acetyltransf_10  40 gkivGvielrdgs.....hisllfVdpeyrgqGigkaLleaveeeaekdgikl.eltvnaspyavpfYeklGFkav 109
                       ++vG i++r  +     +i  ++++++++ +G+g+ L+ ++++++ k+ + + ++   a++ya+++++k+GF++ 
       EEA20156.1 152 LEVVGGITYRPFRgrkfaEIVFCAISSDQQVKGYGAHLMSHLKDYV-KATSDVmHFLTYADNYAIGYFKKQGFTKE 226
                      5677888664333456789999***********************9.6667778*******************875 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.1   1.9e-07   0.00087      12      75 ..     152     224 ..     136     225 .. 0.72

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 1.9e-07
                     TEEEEEEEEEEES....TCTEEEEE-GGGTTSSHHHHHHHH....TTSEEE.....EE.EEEETHHHHHHHHHHTTEE CS
  Acetyltransf_7  12 gkivGfialslld....aeitrlaVdpeyrgkGiGraLlea....aekgii.....le.qlelnaekaikfYeklGFe 75 
                      ++vG i + +      aei + a++ + + kG+G  L+ +    +    +     ++  ++ ++ +ai++++k GF+
      EEA20156.1 152 LEVVGGITYRPFRgrkfAEIVFCAISSDQQVKGYGAHLMSHlkdyV----KatsdvMHfLTYADN-YAIGYFKKQGFT 224
                     467888887777788777888899****************844331....122332343334444.9**********8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (436 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       579  (0.032294); expected 358.6 (0.02)
Passed bias filter:                      389  (0.0216967); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.30s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 2861.36
//
Query:       EEA20157.1  [L=364]
Description: RGS domain protein (Rax1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-12   47.7   0.0      3e-09   37.2   0.0    2.3  2  RGS       Regulator of G protein signaling domain


Domain annotation for each model (and alignments):
>> RGS  Regulator of G protein signaling domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.1   0.0   0.00017       3.1      14      37 ..      34      58 ..      27      90 .. 0.87
   2 !   37.2   0.0   1.7e-13     3e-09      43     112 ..     172     242 ..     153     247 .. 0.93

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00017
                HHHHHHHHTTCT.HHHHHHHHHHHH CS
         RGS 14 lFreFlesefse.enlsFwlaveef 37
                 F  ++++++++ ++l+Fwl+v++ 
  EEA20157.1 34 SFYIYMRDQQRSvDYLDFWLDVSQH 58
                5888999999999*********875 PP

  == domain 2  score: 37.2 bits;  conditional E-value: 1.7e-13
                 HHHHHHHHHHHHHHHTSTTSTTSSTS-HHHHHHHHHHHCSS.STTTTTTHHHHHHHHHHHHHHHHHHHHTS CS
         RGS  43 qeelkkkakeIyneylapsspkelnidkklreelekrleke.qpsrklfeeaqeevfellekdsypkFlks 112
                 + ++ + a++I+ +yl p+s++e+ +++++ +++ + +e + + ++++f++a+++vf+ +e+d++p Fl+ 
  EEA20157.1 172 RTDIRRSAEKILYTYLIPDSEREIVLPSDMLTSIIEMVERDgRDDPEVFDQAKDYVFQAMERDAFPGFLQA 242
                 5678899*******************************999899************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (364 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       544  (0.0303419); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 2522.37
//
Query:       EEA20158.1  [L=389]
Description: RGS domain protein (Rax1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-12   47.4   0.0    3.4e-09   37.0   0.0    2.3  2  RGS       Regulator of G protein signaling domain


Domain annotation for each model (and alignments):
>> RGS  Regulator of G protein signaling domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   0.0   0.00019       3.4      14      37 ..      34      58 ..      27      90 .. 0.87
   2 !   37.0   0.0   1.9e-13   3.4e-09      43     112 ..     172     242 ..     154     247 .. 0.93

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00019
                HHHHHHHHTTCT.HHHHHHHHHHHH CS
         RGS 14 lFreFlesefse.enlsFwlaveef 37
                 F  ++++++++ ++l+Fwl+v++ 
  EEA20158.1 34 SFYIYMRDQQRSvDYLDFWLDVSQH 58
                5888999999999*********875 PP

  == domain 2  score: 37.0 bits;  conditional E-value: 1.9e-13
                 HHHHHHHHHHHHHHHTSTTSTTSSTS-HHHHHHHHHHHCSS.STTTTTTHHHHHHHHHHHHHHHHHHHHTS CS
         RGS  43 qeelkkkakeIyneylapsspkelnidkklreelekrleke.qpsrklfeeaqeevfellekdsypkFlks 112
                 + ++ + a++I+ +yl p+s++e+ +++++ +++ + +e + + ++++f++a+++vf+ +e+d++p Fl+ 
  EEA20158.1 172 RTDIRRSAEKILYTYLIPDSEREIVLPSDMLTSIIEMVERDgRDDPEVFDQAKDYVFQAMERDAFPGFLQA 242
                 5678899*******************************999899************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (389 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       396  (0.0220871); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.31s 00:00:00.80 Elapsed: 00:00:00.45
# Mc/sec: 2598.60
//
Query:       EEA20159.1  [L=342]
Description: COP9 signalosome subunit 7 (CsnG), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
     0.0032   18.0   0.0     0.0065   17.0   0.0    1.5  1  PCI           PCI domain
     0.0098   15.8   0.3      0.016   15.1   0.3    1.3  1  CSN7a_helixI  COP9 signalosome complex subunit 7a helix I dom


Domain annotation for each model (and alignments):
>> PCI  PCI domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0   7.3e-07    0.0065      27      96 ..      83     153 ..      56     156 .. 0.89

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 7.3e-07
                 HHHHHHTTHHHHHHHHHHHHHHHHHHHHHHCESEEEHHHHHHHHTSSH.HHHHHHHHHHHHTTSSSEEEET CS
         PCI  27 eelladdglaqllesLekkvrerllrqvskiyssislerlaklldlsv.devEkilvklIrdgeirakidq 96 
                 +e+ + +gl  l ++   k+r+ +l ++s   + ++++ l ++l +++  ++E+++ ++I++ +i a++++
  EEA20159.1  83 QEYQETPGLPALNDEQALKLRLLSLLTLSSTIRPLTYQALMQALSIPTaAKLESLVTTAIYSSLIVARLSP 153
                 556677888889999999***********************************************999976 PP

>> CSN7a_helixI  COP9 signalosome complex subunit 7a helix I domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.3   1.8e-06     0.016       1      29 [.     175     203 ..     175     213 .. 0.95

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 1.8e-06
  CSN7a_helixI   1 DigaIistLqeWcdsCeaiLsciEtqver 29 
                   D++++is+L eW   C +i ++iE+ +++
    EEA20159.1 175 DVSTLISILSEWEGRCGDIINGIEAEIAK 203
                   99***********************9975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       430  (0.0239835); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2461.17
//
Query:       EEA20160.1  [L=1329]
Description: DNA repair protein Rad50 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      1e-36  127.3   3.2      1e-36  127.3   3.2    7.9  1  AAA_23        AAA domain
    8.6e-08   31.9   0.0    8.6e-08   31.9   0.0    3.4  1  SMC_N         RecF/RecN/SMC N terminal domain
    1.1e-07   31.9  65.9    0.00015   21.6  14.4    5.2  2  AAA_15        AAA ATPase domain
    4.9e-07   29.9  13.5     0.0023   17.8   0.0    4.3  2  AAA_21        AAA domain, putative AbiEii toxin, Type IV TA s
    2.1e-06   27.9   0.0    7.4e-06   26.1   0.0    2.0  1  SbcCD_C       Putative exonuclease SbcCD, C subunit
    0.00068   19.3   0.0     0.0014   18.3   0.0    1.4  1  AAA_29        P-loop containing region of AAA domain
     0.0097   16.2   2.7       0.15   12.3   0.2    3.7  2  Img2          Mitochondrial large subunit ribosomal protein (
  ------ inclusion threshold ------
      0.064   11.9   0.0      0.017   13.8  24.6    7.7  7  AAA_13        AAA domain
      0.068   13.6   0.0      0.068   13.6   0.0    5.6  5  AAA_16        AAA ATPase domain
       0.11   13.0   0.0       0.11   13.0   0.0    7.5  1  ABC_tran      ABC transporter
        0.5   10.6   0.0        0.5   10.6   0.0    5.5  6  DUF3896       Protein of unknown function (DUF3896)


Domain annotation for each model (and alignments):
>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.3   3.2   6.4e-40     1e-36       1     198 [.      35     274 ..      35     276 .. 0.75

  Alignments for each domain:
  == domain 1  score: 127.3 bits;  conditional E-value: 6.4e-40
      AAA_23   1 kLkienfrsf...rdqeidFskgltlItGpNGaGKTTildAiklaLygetprlsrksgrgfeksdveiesegkvkayveltfenkdgrytrsiererel 96 
                 kL+i ++rsf   r ++i+F+ +ltlI+G NG+GKTTi++++k+a++ge p+   +s++g++ +d+++  +++v a+v+l f+ ++g + +  +r+ +l
  EEA20160.1  35 KLSILGVRSFdntRSETIQFHTPLTLIVGYNGSGKTTIIECLKYATTGELPP---NSKGGAFIHDPKLCGDKEVLAQVKLAFKATSGAK-MVATRSLQL 129
                 79********7777789*******************************8665...55689***************************97.888889999 PP

      AAA_23  97 skkkgkttkkaklellei.............deleqfisellgskkiil.nlilflgqerfeefel....kdkke...rleelekeleeledekkllek 174
                 + kk+ +++k+ + +l +             +el+q+++++lg++k+il ++i+++++e+ +++++    k+k++   +  +++k+++ +++ +k++++
  EEA20160.1 130 TVKKTTRQQKTLEGQLLMvkdgertaissrvAELDQIMPQYLGVSKAILdSVIFCHQDESLWPMSEpsvlKKKFDeifEAMKYTKAIDNIKALRKKQNE 228
                 9888888888855554444677888888999******************77777777777888888766666666555333344444444444444444 PP

      AAA_23 175 l......................eqekekekeleeleeeleeilke 198
                 +                      ++  + ++e+e+l+ee   i +e
  EEA20160.1 229 ElakfkimeqhskedkdkadraeKRSIKLQEEIEALREETHRISQE 274
                 4555555554466555544444433334444777777777777666 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.9   0.0   5.3e-11   8.6e-08       2     108 ..      33     138 ..      32     164 .. 0.76

  Alignments for each domain:
  == domain 1  score: 31.9 bits;  conditional E-value: 5.3e-11
                 EEEEEEESETTEECEE.EEEETTSSEEEEEESTTSSHHHHHHHHHHHCTT.TTTTTTCHCCCCCC--.BTTCSSTTEEEEEEEEEETTEESSSSSSCEE CS
                 xxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N   2 lkrleienFksyagkt.vilpfsksftaivGpNGSGKsnlldAilFvLGersakklrseklsdlihk.skekasvkkaeveitfdnedkklkiekeevs 98 
                 + +l i +++s+ +++  +++f++ +t ivG NGSGK+ +++ +++    +      ++k  + ih  +  +++   a+v++ f+ ++ +  + + +++
  EEA20160.1  33 IDKLSILGVRSFDNTRsETIQFHTPLTLIVGYNGSGKTTIIECLKYATTGELP---PNSKGGAFIHDpKLCGDKEVLAQVKLAFKATSGAKMVATRSLQ 128
                 78999*******87651679**************************8764333...578889999997778899999*******988888566555554 PP

                 EEEEEETTSE CS
                 xxxxxxxxxx RF
       SMC_N  99 isrrvkrkge 108
                 +++++ + ++
  EEA20160.1 129 LTVKKTTRQQ 138
                 4444433333 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1  19.7   2.6e-07   0.00043       3     274 ..      33     481 ..      32     549 .. 0.52
   2 !   21.6  14.4   9.4e-08   0.00015      65     368 ..     938    1294 ..     920    1295 .. 0.64

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 2.6e-07
      AAA_15   3 IkkikikNFRslkd...veidlseeltvliGkNnsGKSsilealdlFlnnkekkn............................................ 54 
                 I+k++i   Rs+++    +i++   lt+++G N+sGK++i+e l++  + + + n                                            
  EEA20160.1  33 IDKLSILGVRSFDNtrsETIQFHTPLTLIVGYNGSGKTTIIECLKYATTGELPPNskggafihdpklcgdkevlaqvklafkatsgakmvatrslqltv 131
                 5566665556665522268999999*******************9999988666687788888888888887777777777777666666666665555 PP

      AAA_15  55 ................................................................................................... 54 
                                                                                                                    
  EEA20160.1 132 kkttrqqktlegqllmvkdgertaissrvaeldqimpqylgvskaildsvifchqdeslwpmsepsvlkkkfdeifeamkytkaidnikalrkkqneel 230
                 555555555555555555555555555555555555555555555555555555555555555554444444444444444444444444444444444 PP

      AAA_15  55 ..kkvikiekedleifeniseskdikIdvefaekekakeyektlkskekkkadlllkkkesdlkktikdkklklkknelsdekisvekkks........ 143
                   +k +   +++                                            k+k ++  k++ + + ++++ +  + +is e++++        
  EEA20160.1 231 akFKIMEQHSKED-------------------------------------------KDKADRAEKRSIKLQEEIEALREETHRISQEMRNAadladkaw 286
                 2222222222222...........................................2222222222222222222222222222222222222222222 PP

      AAA_15 144 ................kkelpkekeeklekekeelkidkedlkklikkleeslkkee.......................................... 184
                                 + e  + ++   +++                                                                    
  EEA20160.1 287 kesesyaqvigtlegkRIEARSVQSTIDNLKRH-----------------------Lvevdesdewlqstleqfesrqleyqqqedaqkerymdikeqi 362
                 222222222222222222222222222222222.......................0222222222222222222222222234444444444333333 PP

      AAA_15 185 .........................elknvlksaiiklllisakRnvsdedsekkssllgklkekileealqekl..eeelteklkeiqeklkeidkkl 256
                                          +     ++ i+++   ++ R ++d+++e k + +++ ++k ++e  q     ++e +++  e+q+ l++i +  
  EEA20160.1 363 esnrdqlglkqaevgkyendkdqfeRQIGRRENMIKEFARENNIRGFDDTLDEPKIDEFMRRMQKMVKEHTQALEraRKEGQSEVRETQNVLNQIAQRK 461
                 334466666666666666666665533334456666677788888888888888888888888888887655443666666667777777777665554 PP

      AAA_15 257 aeelk..kilkkkidkikkf 274
                 ++ ++  ++    i++ +k+
  EEA20160.1 462 SAFKEakNVARRQISDNDKE 481
                 43333445555555554333 PP

  == domain 2  score: 21.6 bits;  conditional E-value: 9.4e-08
      AAA_15   65 leifeniseskdikIdvefaek.ekakeyektlkskekkkadlllkkkesdlkktikdkklklkknelsdekisvekkkskkelpkekeeklekeke 160 
                  +++ e +  + + k+d        +ake+e  ++ ++   + ++l+  ++++k++i     +     l+++++++e+++++ +  +e++++ + e++
  EEA20160.1  938 IDQLEPEIAKAQAKLDDIS--RrAEAKERELQQALTRLSDRVNQLNLANDEIKSYIDRGGPEQ----LNKSRKELENIQQEIKKLEEQQSETTREIN 1028
                  4444444444444444333..233444444444445555555667777777788887777775....477777777888877778788888888888 PP

      AAA_15  161 elkidkedlkklikkleeslkkee.........................elknvlksaiiklllisakRnvsdedsekkssllgklkekileealqe 232 
                  +++ + +d +++ ++++ ++++ +                         ++k+  +   +k     a++ ++  + ++k++ l +l+          
  EEA20160.1 1029 KISAQLKDSDNTRRQYSDNISYRQscrlleevqreiqqleeqnaeidrsRFKEESERWTRKHNALAAQQASKMGEMKSKDDQLLQLL---------- 1115
                  888888888888888888888887554444333333333333333333322222233333333333333333333333333333333.......... PP

      AAA_15  233 kleeelteklkeiqeklkeidkklaeelk...................................kilkkkidkikkfnykgkkneeieik....... 287 
                             + ++++k++  ++    k                                   ++++ +++++ +  y g ++ +i i+       
  EEA20160.1 1116 ----------ADWNTDYKDAAANY----KeahikvettkaavddlgryggaldkaimkyhslkmEEINRIVEELWQRTYRGTDVDTILIRsdnenak 1198
                  ..........33333333333333....233345656666666666666666567888888888888888888888889998888888889999999 PP

      AAA_15  288 ...........ddeelplnknG...sGvqrllllillileaekkdekeeknvilliEEPEahLHpqaqkvlikllkelandnkt....QviitTHSp 366 
                              ++  +++++G    G++ l ++i+ ++ ae       +  +++++EP ++L  ++ ++l+++l +++++ ++    Q+i+ TH +
  EEA20160.1 1199 gnrsynyrvcmVKQGAEMDMRGrcsAGQRVLASIIIRLALAECF---GVNCGLIALDEPTTNLDRDNIRSLAESLHDIIKTRQQqanfQLIVITHDE 1292
                  9999999999*555555555542227******************...99**********************************9***********98 PP

      AAA_15  367 hi 368 
                   +
  EEA20160.1 1293 EF 1294
                  76 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   1.4e-06    0.0023       1      42 [.      58      90 ..      58     106 .. 0.74
   2 !    8.7  10.7   0.00086       1.4     219     301 ..    1084    1294 ..     791    1296 .. 0.73

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 1.4e-06
      AAA_21  1 lnvliGpNgsGKSnLLdaldllarldrdvegltdelsggggi 42
                l++++G NgsGK++++++l+++         +t el+++++ 
  EEA20160.1 58 LTLIVGYNGSGKTTIIECLKYA---------TTGELPPNSKG 90
                699****************998.........44555554444 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.00086
      AAA_21  219 r................................................................................................ 219 
                  +                                                                                                
  EEA20160.1 1084 Erwtrkhnalaaqqaskmgemkskddqllqlladwntdykdaaanykeahikvettkaavddlgryggaldkaimkyhslkmeeinriveelwqrty 1180
                  3555555555555555555555555555555555555555555555555555555555555555555555555555555555555555555666666 PP

      AAA_21  220 .......................gvvflengdgqelparel.SdGtkrllalltallralkkg...sllliDEpEngLHPkllrrllell......k 283 
                                         +++    ++g e ++r   S G++ l+ ++  l+ a   g   +l+++DEp ++L+   +r+l+e l      +
  EEA20160.1 1181 rgtdvdtilirsdnenakgnrsyNYRVCMVKQGAEMDMRGRcSAGQRVLASIIIRLALAECFGvncGLIALDEPTTNLDRDNIRSLAESLhdiiktR 1277
                  666666666666666666666666666667777777777777889999988888888888888999*********************9999977743 PP

      AAA_21  284 elsrngaQviltTHSpll 301 
                  + +  + Q+i+ TH+ ++
  EEA20160.1 1278 QQQ-ANFQLIVITHDEEF 1294
                  333.69********9776 PP

>> SbcCD_C  Putative exonuclease SbcCD, C subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.1   0.0   4.6e-09   7.4e-06      12      89 ..    1203    1271 ..    1194    1272 .. 0.85

  Alignments for each domain:
  == domain 1  score: 26.1 bits;  conditional E-value: 4.6e-09
     SbcCD_C   12 fevevr.dedgkekelsrssgtlSGGekqflaylalaaalaalyssaegrepalrlvfLDEAFsklDeesiatllelle 89  
                  ++++v   ++g+e    +++g+ S G++ +la++++ +ala  ++       +++l++LDE   +lD ++i++l e l+
  EEA20160.1 1203 YNYRVCmVKQGAE---MDMRGRCSAGQR-VLASIIIRLALAECFGV------NCGLIALDEPTTNLDRDNIRSLAESLH 1271
                  4444444467777...799*********.*****************......4********************999875 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   8.8e-07    0.0014      15      45 ..      50      79 ..      35      87 .. 0.76

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 8.8e-07
      AAA_29 15 htieidlkg.atlltGpsGsGKSTllDAiqal 45
                +ti+++     tl++G +GsGK+T++  +++ 
  EEA20160.1 50 ETIQFH--TpLTLIVGYNGSGKTTIIECLKYA 79
                455555..558***************888776 PP

>> Img2  Mitochondrial large subunit ribosomal protein (Img2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.3   0.2   9.4e-05      0.15      23      74 ..     814     871 ..     797     876 .. 0.78
   2 ?    1.5   0.2      0.23   3.8e+02      24      56 ..     887     919 ..     880     991 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 9.4e-05
        Img2  23 gtkkltvirkieGDiaalredLrkalee......lvkvnevtgkieikGdrveevkkf 74 
                  ++++t i +i+G+i+ lr++++++l+e      +  ++  ++ i   G+ ++ +k  
  EEA20160.1 814 LSRTVTSIVRIDGEIKSLRSQIAEVLSEqpqgdfSRVLEDIQNDIAAIGEKSRAIKLT 871
                 5789***********************9766654344555677777777777777655 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.23
        Img2  24 tkkltvirkieGDiaalredLrkaleelvkvne 56 
                 +k    +r ++G++a+  ++L+k  + l++v+e
  EEA20160.1 887 NKAELALRDVQGSLANASHELEKKTGLLARVEE 919
                 566667888888888888888887776555554 PP

>> AAA_13  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   3.9e-05     0.064       3      54 ..      42      94 ..      40     137 .. 0.79
   2 ?    0.7  25.2     0.098   1.6e+02     270     466 ..     196     403 ..     171     411 .. 0.64
   3 ?   -1.9  17.0       0.6   9.7e+02     298     460 ..     417     577 ..     403     590 .. 0.68
   4 ?    2.5  15.8     0.026        43      88     379 ..     553     836 ..     551     838 .. 0.70
   5 ?   13.8  24.6     1e-05     0.017     271     470 ..     837    1037 ..     829    1044 .. 0.81
   6 ?   -3.5   6.5       1.8   2.9e+03     115     401 ..    1060    1138 ..    1037    1180 .. 0.47
   7 ?    5.9   0.0    0.0025       4.1     528     605 ..    1247    1321 ..    1207    1327 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 3.9e-05
      AAA_13  3 rif.dfrgaeledfkriNliYGwNGaGKTtLSrllrslelgetepkfangsie 54
                r+f ++r ++++      li G NG+GKTt+ + l+  ++ge  p+ + g+++
  EEA20160.1 42 RSFdNTRSETIQFHTPLTLIVGYNGSGKTTIIECLKYATTGELPPNSKGGAFI 94
                56623334444444557799**********************99999998884 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.098
      AAA_13 270 kaaLeahFddefee.kqerLekliekveskkselleklkavsdeasensafeed....keelkaeaealeeqLkglqraleaKrkepfk...sve.les 359
                    L++ Fd+ fe+ k+ +  + i+ + +k++e+l+k+k + + ++e++  ++       +l++e+eal+e+   +++++ +  +   k   + e + +
  EEA20160.1 196 PSVLKKKFDEIFEAmKYTKAIDNIKALRKKQNEELAKFKIMEQHSKEDKDKADRaekrSIKLQEEIEALREETHRISQEMRNAADLADKawkESEsYAQ 294
                 455777777777652334444455555666666777775554442222211111112233444555555555444444444443222221002221344 PP

      AAA_13 360 vkakiesikklvaeineliakhNekvanleeekeeakkklelhlveeleseld..eykkkykklekaieklekelkeeeaelkkleeeikeLekqlrde 456
                 v + +e    +  +++ +i +  ++  +++e+ e +++ le+++  +le + +  + k+ y +++++ie++ ++l  ++ae+ k+e++  + e+q+   
  EEA20160.1 295 VIGTLEGKRIEARSVQSTIDNLKRHLVEVDESDEWLQSTLEQFESRQLEYQQQedAQKERYMDIKEQIESNRDQLGLKQAEVGKYENDKDQFERQIGRR 393
                 444445555567789999999999999999999999999999998766554443378899*************************************** PP

      AAA_13 457 kpaaeeinke 466
                 ++ ++e+++e
  EEA20160.1 394 ENMIKEFARE 403
                 *****99876 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 0.6
      AAA_13 298 kkselleklkavsdeasensafeedkeelkaeaealeeqLkg.lqraleaKrkepfksvelesvkakiesikklvaeineliakhNekvanleeekeea 395
                 k++e++ +++++++e +  +a e++++e ++e +++++ L++ +qr+   K  + +++ ++++ ++++     +v++  + i     +va le++kee+
  EEA20160.1 417 KIDEFMRRMQKMVKEHT--QALERARKEGQSEVRETQNVLNQiAQRKSAFKEAKNVARRQISDNDKEAA----SVQSRLNEIDVDEGTVAVLESQKEEV 509
                 55667777777777554..46777777777777777777777445555556666666677777777777....44444555777888999999999999 PP

      AAA_13 396 kkklelhlv....eeleseldeykkkykklekaieklekelkeeeaelkkleeeikeLekqlrdekpaa 460
                 ++ le+       ++ +++l+  ++++++le++ +kl++el + ++++  l ++ + ++k+l+d ++  
  EEA20160.1 510 QSRLERLKDvargAKWDKDLQDANTELRSLEDESTKLNQELIAGTKKAGDL-ARLAHMKKELKDRERQL 577
                 999988542345578888888888888888888888888877766665444.34455555555555544 PP

  == domain 4  score: 2.5 bits;  conditional E-value: 0.026
      AAA_13  88 Geesiekqekieklkkeikkleekleaaeaqlqkaekekkklekeledeawkkivkkknsalsealkglkyeekfkerllkelkkknrkaaellsdeel 186
                 G +++ + ++++  kke+k+ e++le+ +    +  ++    ++   d++ +  +++  +++ +++      e++ + + +el++         ++++ 
  EEA20160.1 553 GTKKAGDLARLAHMKKELKDRERQLETMSGAHGDRLSQ-LVSAQWSPDNLER-EYQNVVADVANSM---TLAERNRDGIGRELDQV------EFKLKDC 640
                 56666677777777777777777665544333222222.2222222233322.2233333333333...22333334444444443......4556677 PP

      AAA_13 187 kakletvesenlpelaplslssidldalekaeilkkkvvgkdseieeLienldladWVkqGlelheassdtCpFCgqplpae.....rkaaLeahFdde 280
                  a le+ ++e  + l++++ ++id d  e   il+++    d++ +++ + + +  + +  l   +++ + C+ C +p+++e     +k++Le  + ++
  EEA20160.1 641 RATLEKRKKERDQCLKKIR-DAIDDDPTEYLDILQTRQNHMDQTRKDVEQFAGMHGYFNMCLDALDQK-KMCRTCMRPFKNEtemrtFKNRLEGLIKKN 737
                 7777777777777777777.677777777788888888666899999999999999999999999999.9********998645545899********* PP

      AAA_13 281 feekqerLekliekveskkselleklkavsd.easensafeedkeelkaeaealeeqLkglqraleaKrkepfksvelesvkakiesikklvaeineli 378
                 f  + e+L+++ e++e+++  + + +++    ++++ ++ e++ e+++ ++e++ ++L++    ++++ ++  +  +l+++   i++i  +++++  +i
  EEA20160.1 738 FSSSDEDLKQAEEDYENAR-MVNTDYDTWLRlTETAIPELEKNEEQFQGQKEEILKKLESHDTTVDERAEKKREIESLSRTVTSIVRIDGEIKSLRSQI 835
                 ******************7.58889999998458888899********************999999998554443336777777788888888888888 PP

      AAA_13 379 a 379
                 a
  EEA20160.1 836 A 836
                 6 PP

  == domain 5  score: 13.8 bits;  conditional E-value: 1e-05
      AAA_13  271 aaLeahFddefeekqerLekliekveskkselleklkavsdeasensafeedkeelkaeaealeeqLkglqraleaKrkepfksvelesvkaki... 364 
                  + L +    +f +  e+++++i+ + +k++ ++    ++s+ +se+ ++++d ++++ +++ ++ +L +++ +le+K   +++  e+++++ak    
  EEA20160.1  837 EVLSEQPQGDFSRVLEDIQNDIAAIGEKSRAIKL---TISKLSSEKDQSRDDLNKAELALRDVQGSLANASHELEKKTGLLARVEEYKKSNAKQres 930 
                  4444444456777778888888888888775543...456666777889*****************************9999999998777766555 PP

      AAA_13  365 .esikklvaeineliakhNekvanleeekeeakkklelhlveeleseldeykkkykklekaiekl.ekelkeeeaelkkleeeikeLekqlrdekpa 459 
                   e++  ++++++  iak  +k +++ +++e+ + +l++  + +l + +++++ + ++++  i     ++l+++ +el+++++eik Le+q ++ ++ 
  EEA20160.1  931 iEKADRDIDQLEPEIAKAQAKLDDISRRAEAKERELQQ-ALTRLSDRVNQLNLANDEIKSYIDRGgPEQLNKSRKELENIQQEIKKLEEQQSETTRE 1026
                  5788999***********************99999999.555688999999888888887776541568999999********************** PP

      AAA_13  460 aeeinkeLkaf 470 
                  +++i  +Lk+ 
  EEA20160.1 1027 INKISAQLKDS 1037
                  *****999975 PP

  == domain 6  score: -3.5 bits;  conditional E-value: 1.8
      AAA_13  115 aeaqlqkaekekkklekeledeawkkivkkknsalsealkglkyeekfkerllkelkkknrkaaellsdeelkakletvesenlpelaplslssidl 211 
                   ++++q++e+++ + + +                                                                               
  EEA20160.1 1060 VQREIQQLEEQNAEIDRS------------------------------------------------------------------------------- 1077
                  222222222222222221............................................................................... PP

      AAA_13  212 dalekaeilkkkvvgkdseieeLienldladWVkqGlelheassdtCpFCgqplpaerkaaLeahFddefeekqerLekliekveskkselleklka 308 
                                                                                                                   
  EEA20160.1    - -------------------------------------------------------------------------------------------------    -
                  ................................................................................................. PP

      AAA_13  309 vsdeasensafeedkeelkaeaealeeqLkglqraleaKrkepfksvelesvkakiesikklvaeineliakhNekvanleeekeeakkklel 401 
                                             ++k+ +++ ++K + +++     + ++k+ ++k++ +++ +l a+ N   ++ +++ +ea  k+e 
  EEA20160.1 1078 ---------------------------RFKEESERWTRKHNALAA-----QQASKMGEMKSKDDQLLQLLADWNTDYKDAAANYKEAHIKVET 1138
                  ...........................122222222222222222.....2222223444444444444444444444444444444444443 PP

  == domain 7  score: 5.9 bits;  conditional E-value: 0.0025
      AAA_13  528 kivviDDPvSSLDsnslfivfsliksrl..lkkkkakQlfiLTHnleffkevkkntkrkrkkkeesfyllkk.sqksskik 605 
                  + + +D P   LD + + + +  + + +  ++++   Ql++ TH  ef++ ++ +      + ++ +y++ + ++++s+i+
  EEA20160.1 1247 GLIALDEPTTNLDRDNIRSLAESLHDIIktRQQQANFQLIVITHDEEFLHHMQCA------DFSDYYYRVSRnERQKSIIE 1321
                  5789999******999998888888888533555566*************99876......35566666665344455554 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.0   4.1e-05     0.068      24      47 ..      56      79 ..      43     115 .. 0.82
   2 ?   -0.8   0.3       1.1   1.8e+03      80     132 ..     234     284 ..     193     347 .. 0.64
   3 ?   -0.9   0.6       1.1   1.8e+03      53     116 ..     499     561 ..     433     595 .. 0.65
   4 ?    0.2   0.9      0.53   8.6e+02      76     134 ..     786     865 ..     746     894 .. 0.66
   5 ?    0.5   1.1      0.44   7.1e+02      60     126 ..    1041    1114 ..    1024    1123 .. 0.55

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 4.1e-05
      AAA_16 24 pelvllsGesGvGKsslvrellra 47
                ++l+l++G+ G+GK++++++l+ a
  EEA20160.1 56 TPLTLIVGYNGSGKTTIIECLKYA 79
                4899**************999844 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 1.1
      AAA_16  80 ellrqllde..aesaeleawrekleealaavpelagaeasrllellkrllallsr 132
                 ++++q   e  ++++ +e  + kl+e+++    + ++e +r+ ++++++++l+ +
  EEA20160.1 234 KIMEQHSKEdkDKADRAEKRSIKLQEEIE----ALREETHRISQEMRNAADLADK 284
                 33333333322222222222222222222....2223337777777777766654 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 1.1
      AAA_16  53 giflrgkcdqlesaipysa.laqalareellrqlldeaesaeleawrekleealaavpelagaea 116
                 + +l+ + ++ +s ++++  +a+ +++++ l++ ++e++s  le+ ++kl ++l a+ + ag++a
  EEA20160.1 499 VAVLESQKEEVQSRLERLKdVARGAKWDKDLQDANTELRS--LEDESTKLNQELIAGTKKAGDLA 561
                 4445555555566666655577777777777777777444..55555555555554444444433 PP

  == domain 4  score: 0.2 bits;  conditional E-value: 0.53
      AAA_16  76 lareellrqlldeaesaeleawrekleeala...........avpelagaea...........srllellkrllallsrde 134
                   +ee+l++l++++++ + +a +++  e+l+           ++++l++++a           sr+le +++ +a + +++
  EEA20160.1 786 Q-KEEILKKLESHDTTVDERAEKKREIESLSrtvtsivridgEIKSLRSQIAevlseqpqgdfSRVLEDIQNDIAAIGEKS 865
                 3.4566777777766655555555555555588887777777555555555555555557777777777777765544444 PP

  == domain 5  score: 0.5 bits;  conditional E-value: 0.44
      AAA_16   60 cdqlesaipysalaqalare.ellrqlldeaesaeleawrekleealaavpelagaea......srllellkrl 126 
                   +q++ +i+y +  ++l++  + ++ql+++ ++ ++++++e+ e++++  ++la+++a      ++  ++l +l
  EEA20160.1 1041 RRQYSDNISYRQSCRLLEEVqREIQQLEEQNAEIDRSRFKEESERWTRKHNALAAQQAskmgemKSKDDQLLQL 1114
                  44556679997766666332034555555555555666666666655566666666665555664444444444 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   6.6e-05      0.11      14      32 ..      59      77 ..      54     153 .. 0.91

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 6.6e-05
                EEEEESTTSSHHHHHHHHT CS
                xxxxxxxxxxxxxxxxxxx RF
    ABC_tran 14 vaivGenGaGKStLlklla 32
                + ivG nG+GK+t++++l 
  EEA20160.1 59 TLIVGYNGSGKTTIIECLK 77
                78*************9985 PP

>> DUF3896  Protein of unknown function (DUF3896)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.8       1.3   2.1e+03       7      48 ..     355     396 ..     351     409 .. 0.82
   2 ?   10.6   0.0   0.00031       0.5      14      49 ..     601     637 ..     597     640 .. 0.84
   3 ?   -2.4   0.1       3.3   5.4e+03      28      42 ..     644     658 ..     638     664 .. 0.73
   4 ?    1.2   0.8      0.25   4.1e+02      17      44 ..     786     813 ..     778     821 .. 0.89
   5 ?   -3.3   0.4       6.6   1.1e+04      17      44 ..     909     940 ..     904     945 .. 0.52
   6 ?   -1.2   1.7       1.4   2.3e+03      28      46 ..     999    1017 ..     997    1026 .. 0.85

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 1.3
     DUF3896   7 ynatkkyleekkqqlCkklssltlskkereqlkleidnyeyi 48 
                 y   k  +e  + ql  k +++   + +++q+ ++i   e +
  EEA20160.1 355 YMDIKEQIESNRDQLGLKQAEVGKYENDKDQFERQIGRRENM 396
                 666788999999999999999999999999999999877765 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00031
     DUF3896  14 leekkqqlCkkl.ssltlskkereqlkleidnyeyil 49 
                 le   q++   + +s+tl++++r+ + +e+d  e+ l
  EEA20160.1 601 LEREYQNVVADVaNSMTLAERNRDGIGRELDQVEFKL 637
                 788888876654389*****************99876 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 3.3
     DUF3896  28 ltlskkereqlklei 42 
                 l+  kker+q  + i
  EEA20160.1 644 LEKRKKERDQCLKKI 658
                 555689999965555 PP

  == domain 4  score: 1.2 bits;  conditional E-value: 0.25
     DUF3896  17 kkqqlCkklssltlskkereqlkleidn 44 
                 +k ++ kkl+s   +  er   k+ei+ 
  EEA20160.1 786 QKEEILKKLESHDTTVDERAEKKREIES 813
                 789999********************75 PP

  == domain 5  score: -3.3 bits;  conditional E-value: 6.6
     DUF3896  17 kkqqlCkklssltlsk.kereqlk...leidn 44 
                 kk  l  ++++ + s+ k+re +    ++id 
  EEA20160.1 909 KKTGLLARVEEYKKSNaKQRESIEkadRDIDQ 940
                 55555555555555533667666412244554 PP

  == domain 6  score: -1.2 bits;  conditional E-value: 1.4
     DUF3896   28 ltlskkereqlkleidnye 46  
                  l+ s+ke e +++ei   e
  EEA20160.1  999 LNKSRKELENIQQEIKKLE 1017
                  67799999***99998665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1329 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3380  (0.188521); expected 358.6 (0.02)
Passed bias filter:                      742  (0.0413855); expected 358.6 (0.02)
Passed Vit filter:                       185  (0.0103185); expected 17.9 (0.001)
Passed Fwd filter:                       103  (0.00574488); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 3.09u 0.43s 00:00:03.52 Elapsed: 00:00:00.80
# Mc/sec: 5039.67
//
Query:       EEA20161.1  [L=352]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0039   17.9   0.5      0.012   16.3   0.1    2.0  2  zf-RVT    zinc-binding in reverse transcriptase
  ------ inclusion threshold ------
       0.11   11.8   0.0       0.17   11.1   0.0    1.3  1  CNF1      Rho-activating domain of cytotoxic necrotizing fact
       0.12   12.6   0.1       0.29   11.3   0.1    1.7  1  RNase_H   RNase H


Domain annotation for each model (and alignments):
>> zf-RVT  zinc-binding in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0      0.82   4.9e+03       5      26 ..     137     158 ..     135     182 .. 0.70
   2 !   16.3   0.1     2e-06     0.012      49      80 ..     256     286 ..     242     290 .. 0.77

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.82
      zf-RVT   5 saYkllrekkekvklakliWks 26 
                 ++Ykl+++ + + +  + iW  
  EEA20161.1 137 RIYKLVQTLQRQGNAINAIWVP 158
                 6788888888888888888843 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 2e-06
      zf-RVT  49 nllkrgiesssrCqlCgqeeEtieHlfleCpf 80 
                  l++ g++ +s  + Cgq+ Et+eH +++C+ 
  EEA20161.1 256 YLNRIGAA-DSDLCACGQASETVEHFLFRCTQ 286
                 55666666.6666699**************75 PP

>> CNF1  Rho-activating domain of cytotoxic necrotizing factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   2.9e-05      0.17     139     194 ..     293     350 ..     285     352 .] 0.87

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 2.9e-05
        CNF1 139 GCttivavkegaLyfyhvGkd.eekgdWktareGvsalyqkhlamg.lasvsdsapns 194
                 G   ++  k g+L f+  Gk+  +   W+   + v+a ++  +a g l + ++++p++
  EEA20161.1 293 GMNQCTQTKRGNLSFFLGGKSrSDSDRWQPDMKAVQAAIKYAIATGrLEQEPEPEPQA 350
                 6678999*************9788889*************999987567778887765 PP

>> RNase_H  RNase H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   4.9e-05      0.29      41     126 ..      84     162 ..      43     174 .. 0.63

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 4.9e-05
                 CHHHHHHHHHHHHHHHTT.SC...SEEEEEES-HHHHHHHHCCCHHHHHTTSSSETTSSBHTTHHHHHHHHHCHC.SSEEEEEE-SCCSS CS
     RNase_H  41 qtnnraELsAvieaLkalksd...ekvniytDSkYvvkgitqwvhrwkknawkttseqkpvknkdlaellkelak.kkkvqlkwvkgHaG 126
                 q    aEL A+ +aL+          ++i +  + ++ +i           ++++++++ +++  +++l+++l +  ++++  wv++H+ 
  EEA20161.1  84 QNPYIAELGAIAAALERIPVRtcrRWITILSSNRSALAAIS----------QPRQQSGQKIIQ-RIYKLVQTLQRqGNAINAIWVPAHTD 162
                 33335899999999987433322222334444333333333..........344444445888.899999998985677*********75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (352 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       636  (0.0354733); expected 358.6 (0.02)
Passed bias filter:                      441  (0.024597); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 2381.45
//
Query:       EEA20162.1  [L=432]
Description: GATA transcription factor LreB [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.3e-15   56.7   5.9    2.2e-15   56.0   5.9    1.4  1  GATA          GATA zinc finger
    2.5e-13   50.1   0.0    5.1e-13   49.1   0.0    1.5  1  PAS_3         PAS fold
    2.3e-08   34.0   0.0    5.4e-08   32.8   0.0    1.6  1  PAS           PAS fold
    2.1e-07   31.1   0.0    9.5e-07   29.0   0.0    2.1  2  PAS_9         PAS domain
    7.5e-06   26.0   0.0    1.5e-05   25.1   0.0    1.4  1  PAS_11        PAS domain
    1.3e-05   25.4   0.0    3.3e-05   24.1   0.0    1.7  2  PAS_4         PAS fold
     0.0093   16.1   0.1       0.02   15.0   0.1    1.5  1  Zn-ribbon_8   Zinc ribbon domain
  ------ inclusion threshold ------
      0.079   12.5   0.7       0.88    9.1   0.1    2.7  2  TF_Zn_Ribbon  TFIIB zinc-binding
      0.096   12.7   0.1       0.73    9.9   0.0    2.4  2  FmdE          FmdE, Molybdenum formylmethanofuran dehydrogena
       0.13   12.2   2.1       0.14   12.1   0.1    2.0  2  DUF4428       Domain of unknown function (DUF4428)


Domain annotation for each model (and alignments):
>> GATA  GATA zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.0   5.9   1.2e-18   2.2e-15       1      36 []     386     421 ..     386     421 .. 0.97

  Alignments for each domain:
  == domain 1  score: 56.0 bits;  conditional E-value: 1.2e-18
        GATA   1 CsnCgttkTplWRrgpdgnksLCnaCGlyykkkglk 36 
                 C+ Cgt  +p+WR+gp+g+k+LCnaCGl+++kk++k
  EEA20162.1 386 CTDCGTLASPEWRKGPSGPKTLCNACGLRWAKKERK 421
                 *********************************975 PP

>> PAS_3  PAS fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.1   0.0   2.8e-16   5.1e-13       2      75 ..     113     184 ..     112     194 .. 0.94

  Alignments for each domain:
  == domain 1  score: 49.1 bits;  conditional E-value: 2.8e-16
       PAS_3   2 iyvserveeilGyspeellgkveswldlvhpeDrervrealqealkkgepyegeyRirrkdGeyrwveararvi 75 
                 +y+s+++e i+ y p +l g+  ++ ++vh +Dr  + ++++e++++g+++  ++R+r+ dGe + vea++ ++
  EEA20162.1 113 LYCSPAIEPITKYKPKDLGGR--FVSEFVHDDDRTSFIREFNESIATGHRLRYHFRFRKSDGEFTIVEASGHAH 184
                 8********************..************************************************988 PP

>> PAS  PAS fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.8   0.0     3e-11   5.4e-08       4     101 ..      93     189 ..      92     196 .. 0.86

  Alignments for each domain:
  == domain 1  score: 32.8 bits;  conditional E-value: 3e-11
                 HHHHHHSSSEEEEEETTSBEEEECHHHHHHHSSTHHHCTTSBGGGGBSTTHHHHHHHHHHHHHHHTT-ECCCCEEEECTTSSEEEEEEEEEEEEETTE CS
         PAS   4 raileslpdpifvvDedgrilyvNaaaeellGlsreevlgkslldliheeddaelaelleqlleqgeesrageisfklrdgrpihlevraspvrdagg 101
                 ++il  + d  +v+  dg++ly+++a+e ++ ++++++ g+ +++++h +d+  + +++ + +++g++ r +  +f++ dg+++ +e   +  +++++
  EEA20162.1  93 QRILAEMQDILIVLSPDGKVLYCSPAIEPITKYKPKDLGGRFVSEFVHDDDRTSFIREFNESIATGHRLR-YHFRFRKSDGEFTIVEASGHAHMSREK 189
                 789999*****************************************99998888888888887776555.567777789999999999988888876 PP

>> PAS_9  PAS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.0   0.0   5.3e-10   9.5e-07       4      82 ..     103     181 ..     100     193 .. 0.90
   2 ?   -1.9   0.0       2.2     4e+03      44      66 ..     226     247 ..     216     265 .. 0.57

  Alignments for each domain:
  == domain 1  score: 29.0 bits;  conditional E-value: 5.3e-10
       PAS_9   4 ilidnpdgrilyaNeaalrllGyspeevlgksitdlfvtdpeanerlraaleqgrk.kerevevvlirkngetfwvllta 82 
                  ++  pdg++ly+++a + ++ y+p+++ g+ +++++ +d+++ +++r++ e++ + +  ++   +++++ge   v+++ 
  EEA20162.1 103 LIVLSPDGKVLYCSPAIEPITKYKPKDLGGRFVSEFV-HDDDRTSFIREFNESIATgHRLRYHFRFRKSDGEFTIVEASG 181
                 34477********************************.*********************************999988776 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 2.2
       PAS_9  44 peanerlraaleqgrkkerevev 66 
                 + +n rl++ + +++ ke+e+e+
  EEA20162.1 226 KVENIRLNRRIADLK-KEEEEEL 247
                 555555555555555.3333332 PP

>> PAS_11  PAS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1   0.0   8.3e-09   1.5e-05       6      90 ..     104     184 ..     100     191 .. 0.91

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 8.3e-09
      PAS_11   6 trldidgkIisvDtsaLrasfslglekeelvgrsiydLchpqdlstlkshlrevissngeatsslyRLrlsqdkfvkvktksklf 90 
                 + l++dgk++ + +    ++  ++++ ++l gr + +++h +d+++  + + e i  +g+     +R+r s+++f  v + ++  
  EEA20162.1 104 IVLSPDGKVLYCSP---AIEPITKYKPKDLGGRFVSEFVHDDDRTSFIREFNESI-ATGHRLRYHFRFRKSDGEFTIVEASGHAH 184
                 67899*********...99999999999***************************.*******************9999988765 PP

>> PAS_4  PAS fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.0   1.8e-08   3.3e-05       3      76 ..      98     172 ..      96     193 .. 0.87
   2 ?   -3.5   0.0         7   1.3e+04      19      37 ..     231     249 ..     228     257 .. 0.77

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 1.8e-08
       PAS_4   3 slpdalavldpdgrvlyaNaaaaelfgappeellGktlaellpeedaarleralrrvlegeepiefleelll.pg 76 
                  ++d+l+vl+pdg+vly+++a++ + ++ p++l G+ + e++ ++d++ + r  ++ ++++++++ +   +  +g
  EEA20162.1  98 EMQDILIVLSPDGKVLYCSPAIEPITKYKPKDLGGRFVSEFVHDDDRTSFIREFNESIATGHRLRYHFRFRKsDG 172
                 6899*******************************************************9998877666555455 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 7
       PAS_4  19 yaNaaaaelfgappeellG 37 
                 ++N+++a+l + + eel+ 
  EEA20162.1 231 RLNRRIADLKKEEEEELRA 249
                 5788888888888888875 PP

>> Zn-ribbon_8  Zinc ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.1   1.1e-05      0.02       5      34 ..     383     413 ..     383     418 .. 0.85

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.1e-05
  Zn-ribbon_8   5 eYrCeeCghefe.vlqsisdapltaCPeCgs 34 
                  eY C++Cg+    ++++    p+t C +Cg 
   EEA20162.1 383 EYVCTDCGTLASpEWRKGPSGPKTLCNACGL 413
                  8*******88888888877999999****96 PP

>> TF_Zn_Ribbon  TFIIB zinc-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.1   0.00049      0.88      17      28 ..     381     392 ..     379     398 .. 0.86
   2 ?    0.1   0.1      0.33   5.9e+02      20      27 ..     406     413 ..     405     416 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00049
                   TTCEEESSSSBE CS
  TF_Zn_Ribbon  17 rgelvCtdCGlV 28 
                   + e+vCtdCG++
    EEA20162.1 381 TDEYVCTDCGTL 392
                   569*******75 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.33
                   EEESSSSB CS
  TF_Zn_Ribbon  20 lvCtdCGl 27 
                   ++C +CGl
    EEA20162.1 406 TLCNACGL 413
                   68*****8 PP

>> FmdE  FmdE, Molybdenum formylmethanofuran dehydrogenase operon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.1      0.95   1.7e+03     103     120 ..     239     256 ..     214     262 .. 0.59
   2 ?    9.9   0.0   0.00041      0.73      30      60 ..     306     341 ..     285     399 .. 0.72

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.95
                 GGGS-HHHHHHHHHHHHH CS
        FmdE 103 keekeeeeleeeleeaik 120
                  +++eeeel+ ++++ ++
  EEA20162.1 239 LKKEEEEELRAQQQWVLQ 256
                 223355566667666654 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.00041
                 T....SSSEEEEES-S.TCHHHHHHHHCS--TTTTS CS
        FmdE  30 g....deelvaivetd.sCldDAiqvltgctlGkgn 60 
                 +    d +l++i++ d s+  D+i +ltg ++G g 
  EEA20162.1 306 SmitlDNNLDTISRSDtSSVLDGIEMLTGLRYGEGE 341
                 14445899*******9999**************953 PP

>> DUF4428  Domain of unknown function (DUF4428)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.1     8e-05      0.14      13      27 ..     376     390 ..     372     399 .. 0.86
   2 ?   -2.2   0.2       2.2     4e+03      21      26 ..     406     411 ..     405     418 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 8e-05
     DUF4428  13 krlkleDgyvCkdCl 27 
                 kr+k+ D+yvC+dC 
  EEA20162.1 376 KRIKTTDEYVCTDCG 390
                 5699**********5 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 2.2
     DUF4428  21 yvCkdC 26 
                 ++C++C
  EEA20162.1 406 TLCNAC 411
                 589999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (432 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       614  (0.0342462); expected 358.6 (0.02)
Passed bias filter:                      476  (0.0265492); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.41
# Mc/sec: 3151.61
//
Query:       EEA20163.1  [L=397]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-09   36.4   3.2    1.7e-08   34.5   3.2    2.2  1  PPP4R2    PPP4R2


Domain annotation for each model (and alignments):
>> PPP4R2  PPP4R2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.5   3.2   9.2e-13   1.7e-08      90     251 ..     135     357 ..       5     396 .. 0.56

  Alignments for each domain:
  == domain 1  score: 34.5 bits;  conditional E-value: 9.2e-13
      PPP4R2  90 naaPFTiqRicELltdPkkyYkeldKFvrAleKnilVvStiepggkreseaeeeksnsesseniingvlseelnse....................... 165
                 ++ P T+qR+ EL   P ++Y++l  ++rA+++ + V S+ +            ++++e  + i ng+ s  +  +                       
  EEA20163.1 135 SKPPHTVQRLAELILRPTRQYRTLPAYLRAVDRVVSVSSCADIFPLP---RTGYSPDDELANGITNGARSSFMVTDeslgsdeslggalltpipwlrnh 230
                 457*************************************9644433...2234455555555555533222222234444455666666666666666 PP

      PPP4R2 166 .............................keedkansssqedsedvslvsipwvdekteselspfikeidsimsvnlgfedeeekeedd.........n 226
                                               +e++a    ++++  vs   +   +e++++++sp+ +ei    + +  + ++   ++ +         n
  EEA20163.1 231 dleavqaemiaegavplradaavtqgeliRQEQEAGLIATSQTPHVSSRYLTE-NEEDGENSSPQPEEIPHARGPSVLGVEDLGLQDGKgvemvlsdpN 328
                 66665555555555555555554444333222222222222222222222222.333333444444444433333333333322222223444433321 PP

      PPP4R2 227 eseesaseseeiteekdesvkvee.....k 251
                  +++++++se++++ + e  + +e      
  EEA20163.1 329 -NKSQEEKSEMDVSDSAEGLIPDEvvsetV 357
                 .11222222222222222222222444322 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       610  (0.0340231); expected 358.6 (0.02)
Passed bias filter:                      395  (0.0220313); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.30s 00:00:00.84 Elapsed: 00:00:00.47
# Mc/sec: 2561.66
//
Query:       EEA20164.1  [L=573]
Description: phosphoribosyl-aminoimidazole carboxylase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.1e-59  198.4   0.7    9.2e-59  197.3   0.7    1.6  1  AIRC             AIR carboxylase
    5.1e-53  179.1   0.0    1.1e-52  178.1   0.0    1.6  1  ATP-grasp        ATP-grasp domain
    4.6e-18   64.7   0.1    9.4e-18   63.7   0.1    1.6  1  PurK_C           Phosphoribosylaminoimidazole carboxylase C-t
    1.9e-05   24.3   0.2    5.3e-05   22.8   0.0    1.8  2  CPSase_L_D2      Carbamoyl-phosphate synthase L chain, ATP bi
    6.9e-05   22.5   0.4     0.0068   16.0   0.0    2.9  3  PrpR_N           Propionate catabolism activator
    9.6e-05   22.0   0.0    0.00057   19.5   0.0    2.1  1  Dala_Dala_lig_C  D-ala D-ala ligase C-terminus
      0.001   18.4   0.0     0.0022   17.3   0.0    1.5  1  AlaDh_PNT_C      Alanine dehydrogenase/PNT, C-terminal domain
     0.0012   18.2   0.0     0.0023   17.3   0.0    1.4  1  2-Hacid_dh_C     D-isomer specific 2-hydroxyacid dehydrogenas
     0.0048   16.8   0.1      0.014   15.3   0.1    1.8  1  3HCDH_N          3-hydroxyacyl-CoA dehydrogenase, NAD binding
     0.0094   16.1   0.0      0.027   14.6   0.0    1.8  1  NAD_binding_2    NAD binding domain of 6-phosphogluconate deh
  ------ inclusion threshold ------
      0.016   15.7   0.4      0.067   13.8   0.1    2.3  2  F420_oxidored    NADP oxidoreductase coenzyme F420-dependent
      0.055   14.0   0.1       0.29   11.6   0.0    2.1  2  XdhC_C           XdhC Rossmann domain
      0.056   13.5   0.0        5.9    7.0   0.0    3.2  4  Peptidase_M15_3  Peptidase M15
       0.06   13.4   0.1       0.21   11.6   0.0    2.1  2  ATP-grasp_3      ATP-grasp domain
       0.12   12.8   0.5         15    6.1   0.0    3.2  3  CoA_binding_2    CoA binding domain
       0.12   11.8   0.1        0.2   11.1   0.1    1.3  1  Epimerase        NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> AIRC  AIR carboxylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  197.3   0.7   8.2e-62   9.2e-59       2     145 ..     405     549 ..     404     552 .. 0.98

  Alignments for each domain:
  == domain 1  score: 197.3 bits;  conditional E-value: 8.2e-62
                 EEEEESSGGGHHHHHHHHHHHHH.TT-EEEEEE--TTTSHHHHHHHHHHCHTTTEEEEEEEEESS--HHHHHHHHSSS-EEEEEE--STTCCHHHHHHH CS
        AIRC   2 VgiimGSdsDlevmkkaaeilke.lgveyevrvvSahrtpeelleyaeeaeerglkviIagAGgaahLpgvvaslttlPVigvPvkskalkgldsllSi 99 
                 +g+imGSdsDl+++    ++l++ +g++ ev+++Sahrtpe ++eya++a++rg+kviIa+AGgaahLpg+ a++t lPVigvPvk +al+g+dsl+Si
  EEA20164.1 405 IGVIMGSDSDLKTLVPGLKLLRDyFGIDPEVDITSAHRTPEYMAEYASKAASRGIKVIIAAAGGAAHLPGMAAAHTALPVIGVPVKGSALDGVDSLYSI 503
                 89*******************999*************************************************************************** PP

                 HT--TTS--EE-SSTHHHHHHHHHHHHHTTT-HHHHHHHHHHHHHH CS
        AIRC 100 vqmPsgvpvatvaigkaknAallAaqilalkdeelaekleeyreel 145
                 vqmP+gvpvatv+i+++ nAallA++il+  +++l++k+eey ++ 
  EEA20164.1 504 VQMPRGVPVATVGINNSINAALLAVRILGSYEPALQRKVEEYATNA 549
                 ******************************************9875 PP

>> ATP-grasp  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  178.1   0.0   9.8e-56   1.1e-52       2     171 .]     113     284 ..     112     284 .. 0.95

  Alignments for each domain:
  == domain 1  score: 178.1 bits;  conditional E-value: 9.8e-56
                 HTTT--B-EEEEECCHH..HHHHHHHHH-SCEEEEESSS-CTTTTEEEECTCCGHHCHHHHCGTTCEEEEE----SEEEEEEEEEETTC-EEE--EEEE CS
   ATP-grasp   2 eklglpvprflaveske..eleeaaeelglpvvvKarrlgydGkGqsvvrseedleqalealkeekvivEefvpfekElsvlvvrsaeGetafypvvet 98 
                 +k  +p++++  + +++  el ++ e lg+p+++K+++l+ydG+G++ v+s+ed+++alealk++++++E++++f++El+v+vv++++  + +yp+vet
  EEA20164.1 113 SKYDIPMADYRELVENTpeELAKIGEYLGYPMMLKSKTLAYDGRGNYPVKSKEDIPEALEALKDRPLYAEKWAHFKMELAVIVVKTKDS-VLSYPTVET 210
                 57789*****988666556*********************************************************************8.********* PP

                 EEETTEEEEEEECEE.-SCHHHHHHHHHHHHHHHHHTSSEEEEEEEEEETTCTEEEEEEESS--GGGGGHHHHB CS
   ATP-grasp  99 vqedgilrlsvapae.vsekaqkkaeeiakkiveeLggvGvfavElFvledgellvnElapRpHnsGhvtldaa 171
                 vqed i++l++apa+ vs++++kka+e+a+++v++++g G+f+vE+F+led+++l+ E+a R+HnsGh+t++++
  EEA20164.1 211 VQEDSICKLVYAPARnVSDAINKKAQELARNAVAAFEGKGIFGVEMFLLEDDSILLCEIASRVHNSGHYTIEGC 284
                 *************9637888****************************************************98 PP

>> PurK_C  Phosphoribosylaminoimidazole carboxylase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.7   0.1   8.4e-21   9.4e-18       1      54 [.     312     369 ..     312     371 .. 0.92

  Alignments for each domain:
  == domain 1  score: 63.7 bits;  conditional E-value: 8.4e-21
      PurK_C   1 avMvNlLGedae....ekleellaipgahlHlYgKeearpgRKmGHitvvgdsaeele 54 
                 ++M+N++G +++    +  e++l+ip+a++HlY K  arpgRKmGH+tv+g+++ e+e
  EEA20164.1 312 SIMLNIIGGATSdshlRVAEHALSIPNASIHLYSKGAARPGRKMGHVTVTGATMYEAE 369
                 79*********8877777777********************************99887 PP

>> CPSase_L_D2  Carbamoyl-phosphate synthase L chain, ATP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8   0.0   4.7e-08   5.3e-05       4     186 ..     107     279 ..     104     295 .. 0.83
   2 ?   -3.4   0.1       4.9   5.5e+03      21      48 ..     441     468 ..     436     478 .. 0.76

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 4.7e-08
                  HHHHHHHHTT-BBSSEECSSBSSHHHHHHHHHHH-SSEEEEE.TTCCTTTTEEEESSHHHHHHHHHHHHHHHHHHHSTS-EEEEE--SSSEEEEEEEE CS
  CPSase_L_D2   4 sakealkkinvpvvpssaapvetleealaiakeigyPviika.afglGGkGmrvarneeelaelvkkalaeakaafgnkqvlvekslkgpkeiEvevl 100
                    k+ l+k ++p+++  + + +t ee  +i + +gyP+++k+ + +  G+G   ++++e++ e++++  +        + ++ ek+ +   e+ v v+
   EEA20164.1 107 DQKKHLSKYDIPMADYRELVENTPEELAKIGEYLGYPMMLKSkTLAYDGRGNYPVKSKEDIPEALEALKD--------RPLYAEKWAHFKMELAVIVV 196
                  567889999**********99********************846799**************998864443........45999999776666655555 PP

                  EETTS-EEEEEEEEECCECTCCCCEEEES-SS--HHHHHHHHHHHHHHHHHHT-EEEEEEEEEEETTTTEEEEEEEESS--CCHHH CS
  CPSase_L_D2 101 rDakgnvitvcerenslqlrtqkvievAPsqtLtdeerqalreaavkvvrevgvvgagtveflldpkskeyyviEvNtRlsvesal 186
                    +k+ v+   + e + +    k+ + AP++ ++d+  ++ +e a ++v + + +g   ve  l + ++++ + E+ +R+  +   
   EEA20164.1 197 -KTKDSVLSYPTVETVQEDSICKL-VYAPARNVSDAINKKAQELARNAVAAFEGKGIFGVEMFLLE-DDSILLCEIASRVHNSGHY 279
                  .57789999999999887777775.68*********999999999999999999999899966654.79999*******9987655 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 4.9
                  CSSBSSHHHHHHHHHHH-SSEEEEETTC CS
  CPSase_L_D2  21 aapvetleealaiakeigyPviikaafg 48 
                  +++ e + e  + a++ g  vii aa g
   EEA20164.1 441 HRTPEYMAEYASKAASRGIKVIIAAAGG 468
                  5556677788888889999999998876 PP

>> PrpR_N  Propionate catabolism activator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.0     0.051        57      52     113 ..      28      91 ..       9      93 .. 0.78
   2 ?   -2.1   0.0       2.3   2.5e+03     100     118 ..     159     177 ..     158     179 .. 0.87
   3 !   16.0   0.0   6.1e-06    0.0068       4      93 ..     434     531 ..     432     561 .. 0.76

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.051
      PrpR_N  52 eikvsgyDilralkqakklg..ekialvgfeniikglktlselldldieiytinseeeaeaavk 113
                 +i+v + D  +a ++    +    i+ ++ ++ +++l++ ++++  +ie+      e + ++vk
  EEA20164.1  28 NIEVHVLDAASAPAKQISAHdsHTIGHFNDQESVQELAKTCDVVTAEIEHVNTYALEAVASQVK 91 
                 6777777777776555444423479*************************99999998888886 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 2.3
      PrpR_N 100 ytinseeeaeaavkelkae 118
                 y+++s e++++a++ lk++
  EEA20164.1 159 YPVKSKEDIPEALEALKDR 177
                 789999*******999975 PP

  == domain 3  score: 16.0 bits;  conditional E-value: 6.1e-06
      PrpR_N   4 eldievvegdleeavelakeleaegvdviiSrGgtaell....rkhvsvPVveikvsgy..Dilralkqakklge..kialvgfeniikglktlsell 93 
                 e+di+  + + e  +e+a +++++g++vii++ g a+ l     +h+ +PV+ ++v+g   D + +l+++ +  +   +a vg +n i+++    ++l
  EEA20164.1 434 EVDITSAHRTPEYMAEYASKAASRGIKVIIAAAGGAAHLpgmaAAHTALPVIGVPVKGSalDGVDSLYSIVQMPRgvPVATVGINNSINAALLAVRIL 531
                 78899999999999*****************999999874544799*******999764337777777777766434688888888777766655555 PP

>> Dala_Dala_lig_C  D-ala D-ala ligase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0   5.1e-07   0.00057       4     172 ..     114     269 ..     111     272 .. 0.77

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 5.1e-07
                      HTT--B--EEEEETTHHCH-H-HHHHHHHHHC-SSEEEEESSSS.TTTTEEEESSGGGHHHHHHHHHTT-SCEEEEE--.ESEEEEEEEEETSS CS
  Dala_Dala_lig_C   4 aaGlpvvpyvvlekeeakeekkellekveeelgypvfVKpareG.SSvGvskveseeelkeaieeafkydekvlvEeai.egreievavlgnek 95 
                      + ++p+++y  l +++      e l+k+ e lgyp++ K+  +     G   v+s+e++ ea+e+   +d+    E++     e+ v v++  +
       EEA20164.1 114 KYDIPMADYRELVENTP-----EELAKIGEYLGYPMMLKSKTLAyDGRGNYPVKSKEDIPEALEAL--KDRPLYAEKWAhFKMELAVIVVKTKD 200
                      56677777766655444.....44569************987652568***************975..6999******9556799999998555 PP

                      CEEE.EEEEEE-SSSSS-HHHHHC.TT-EEESS----HHHHHHHHHHHHHHHHHTT--SEEEEEEEEETTTEEEEEEE CS
  Dala_Dala_lig_C  96 levs.evgeivvkkgfydyeakysddkaqlevpaklekeveekiqelalkaykaldlrGlaRvDfflteegeivlnEv 172
                         s +++e v+++++    +k +     +    ++++++++k qela +a +a +++G+  v +fl e+++i+l E+
       EEA20164.1 201 SVLSyPTVETVQEDSI----CKLV-----YAPARNVSDAINKKAQELARNAVAAFEGKGIFGVEMFLLEDDSILLCEI 269
                      4444044454444444....4443.....44456899***************************************98 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0     2e-06    0.0022      30      96 ..       7      72 ..       3      81 .. 0.90

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 2e-06
                 EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTTCECEEHCHHHHHHHHHHHH-SEEE CS
  AlaDh_PNT_C 30 kvlviGgGvaGlqAiatakglgakVtvlDvrparleqleslgakfvevlksqeellaeavkeadvvi 96
                 kv ++GgG  G    + a++l+ +V vlD  +a ++q+++  ++++  + +++e+++e +k++dvv 
   EEA20164.1  7 KVGILGGGQLGRMLTESANRLNIEVHVLDAASAPAKQISAHDSHTIG-HFNDQESVQELAKTCDVVT 72
                 899*************************************9999666.56778899********995 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0   2.1e-06    0.0023      38      98 ..       7      74 ..       2      81 .. 0.81

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 2.1e-06
                  EEEEES-SHHHHHHHHHHHHTT-EEEEESSSHHHHH.....CHHHHTC..EECSHHHHHHH-SEEEE- CS
  2-Hacid_dh_C 38 tvGiiGlGrIGqavakrlkafgmkviaydrskkkee.....eeeelgv..elvsleellaesDivslh 98
                  +vGi+G G++G+ + + ++ ++++v + d    + +     + ++ g   + +s++el +++D+v+  
    EEA20164.1  7 KVGILGGGQLGRMLTESANRLNIEVHVLDAASAPAKqisahDSHTIGHfnDQESVQELAKTCDVVTAE 74
                  89***************************9988777666543333333345679***********976 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.1   1.2e-05     0.014       1      72 [.       7      80 ..       7     112 .. 0.80

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 1.2e-05
                EEEEE--SCCHHHHHHHHHHTT-EEEEE-S-HHHHHHHHHHHHHHHHCCTTTTSS-..HHHHCCCHHCEEEES- CS
     3HCDH_N  1 kvaviGaGtmGagiaavfasagleVvlvdiseealekalekieksleklvekgklk..eeeveaalarisfttd 72
                kv+++G G++G+ +++ + + ++eV+++d +++ +++  ++ ++++ ++  +++++  +++++ + a+i+  + 
  EEA20164.1  7 KVGILGGGQLGRMLTESANRLNIEVHVLDAASAPAKQISAHDSHTIGHFNDQESVQelAKTCDVVTAEIEHVNT 80
                79******************************999999999999999998888888444455555555554443 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   2.5e-05     0.027       1      65 [.       7      77 ..       7     105 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 2.5e-05
                   EEEEE--SHHHHHHHHHHHHTT-EEEEE-SSHHHHHHHHHTT......EEE-SSHHHHHHHCSEEEE-SSS CS
  NAD_binding_2  1 kigfiGlGvMGsnmalnllkagykvavynrtkekveelvaeg......akaaesieelvasldvvitmvka 65
                   k+g++G G++G+ + +   + +++v+v +  ++ ++++ a+       ++  es++el++++dvv   +++
     EEA20164.1  7 KVGILGGGQLGRMLTESANRLNIEVHVLDAASAPAKQISAHDshtighFNDQESVQELAKTCDVVTAEIEH 77
                   69***********************************9999888888899999999999999999887764 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.1     6e-05     0.067       1      81 [.       7      90 ..       7     101 .. 0.73
   2 ?   -2.8   0.0       8.6   9.6e+03      33      48 ..     441     459 ..     431     471 .. 0.57

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 6e-05
                   EEEEETTSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC-EEECECHHHHHHH-SEEEE...-S-HHHHHHHHHHC CS
  F420_oxidored  1 kigiiGaGnmgealasgllaagaqpheivvansrnpekaeelaeelgvkvtavdneeaaeeadvvvl...avkpedveevlsel 81
                   k+gi+G+G++g+ l++ + + + + h +  a+ + ++  ++   ++g    + + +e+a+ +dvv      v ++++e+v+s++
     EEA20164.1  7 KVGILGGGQLGRMLTESANRLNIEVHVLDAASAPAKQISAHDSHTIGHFNDQESVQELAKTCDVVTAeieHVNTYALEAVASQV 90
                   79*******************966666665555555555666677777777779999999***995411145666666666666 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 8.6
                    ESSCCCHHHHHHHHC...- CS
  F420_oxidored  33 srnpekaeelaeelg...v 48 
                    +r+pe ++e a+++    +
     EEA20164.1 441 HRTPEYMAEYASKAAsrgI 459
                    6666666666655442333 PP

>> XdhC_C  XdhC Rossmann domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   0.00026      0.29       3      63 ..      10      85 ..       8     114 .. 0.70
   2 ?   -1.0   0.0       2.1   2.4e+03      13      65 ..     133     212 ..     127     236 .. 0.64

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00026
                EE--STTHHHHHHHHHHHTEEEEEEES-GGGG.........-GGG-TT-SE..............-EEEE--S-HHHHHHHHHH CS
      XdhC_C  3 ifGaghvaqalarlaaalgfrvtvvdpreefa.........tkerfpeade..............tavvvlthdhklDaealea 63
                i+G+g+ ++ l + a++l+++v+v+d+ ++ a         t                       t+ vv  +  +  + alea
  EEA20164.1 10 ILGGGQLGRMLTESANRLNIEVHVLDAASAPAkqisahdshT--------IghfndqesvqelakTCDVVTAEIEHVNTYALEA 85
                99*************************997664444444442........0333334445555555555555555555555555 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 2.1
                 HHHHHHHHTEEEEEEES-GGGG........-GGG-TT-SE...................-EEEE--S-HHHHHHHHHHHS CS
      XdhC_C  13 larlaaalgfrvtvvdpreefa........tkerfpeade...................tavvvlthdhklDaealeaal 65 
                 la++++ lg+ +++  +  ++         +ke++pea e                   +++vv t+d  l ++ +e++ 
  EEA20164.1 133 LAKIGEYLGYPMMLKSKTLAYDgrgnypvkSKEDIPEALEalkdrplyaekwahfkmelAVIVVKTKDSVLSYPTVETVQ 212
                 55666666665555554445553333334455555544447777777777777777777778888888777777777666 PP

>> Peptidase_M15_3  Peptidase M15
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0       9.5   1.1e+04       5      24 ..      61      80 ..      54      92 .. 0.61
   2 ?   -2.9   0.0       6.4   7.2e+03      27      50 ..     125     148 ..     107     149 .. 0.77
   3 ?    2.3   0.0      0.15   1.7e+02      60      72 ..     317     329 ..     287     342 .. 0.72
   4 ?    7.0   0.0    0.0052       5.9      28      58 ..     415     447 ..     397     459 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 9.5
  Peptidase_M15_3  5 vaelalsdkavrkgidnapt 24
                     v+ela++++ v+  i + +t
       EEA20164.1 61 VQELAKTCDVVTAEIEHVNT 80
                     55666666666666654443 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 6.4
  Peptidase_M15_3  27 avqkllaklealreklgkpivvtS 50 
                       v+++ ++l ++ e+lg p+++ S
       EEA20164.1 125 LVENTPEELAKIGEYLGYPMMLKS 148
                      377888899999999999999877 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.15
  Peptidase_M15_3  60 kvGGatdsqHltg 72 
                       +GGat++ Hl+ 
       EEA20164.1 317 IIGGATSDSHLRV 329
                      48********985 PP

  == domain 4  score: 7.0 bits;  conditional E-value: 0.0052
  Peptidase_M15_3  28 vqkllaklealreklgk..pivvtSgyRseevn 58 
                      ++ l+  l+ lr+++g    + +tS++R++e+ 
       EEA20164.1 415 LKTLVPGLKLLRDYFGIdpEVDITSAHRTPEYM 447
                      567888999*******9978*********9975 PP

>> ATP-grasp_3  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0       1.9   2.2e+03      37      99 ..      42     105 ..      37     151 .. 0.58
   2 ?   11.6   0.0   0.00019      0.21     112     159 ..     227     274 ..     102     276 .. 0.77

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 1.9
                  EESS-------B--SS--TTE.......EEEE---S.EEEEEEEEE.SSSEEEEEEEEEEEET. CS
  ATP-grasp_3  37 KprdGaggesvrvveekeeaeaaieevelvqefieG.kplSvsllsdgekvlvlavnrqlieka 99 
                  K +++ +++ +  ++++e+ ++  ++  +v + ie  + + +++++++ kv +   +  +i+++
   EEA20164.1  42 KQISAHDSHTIGHFNDQESVQELAKTCDVVTAEIEHvNTYALEAVASQVKVEPSWQSIRIIQNK 105
                  6666667777777777766666666666666666641345556666555555555444455443 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 0.00019
                  ----HHHHHHHHHHHHHTTSTT--EEEEEEE.EESS.SEEEEEEESS-- CS
  ATP-grasp_3 112 ietelkeevvelaeevvekleglaGyvGvDl.vlkdeepyviEvNPRlt 159
                  +    +++++ela+++v+++ + +G++Gv++ +l+d+ + + E+ +R+ 
   EEA20164.1 227 VSDAINKKAQELARNAVAAF-EGKGIFGVEMfLLEDDSILLCEIASRVH 274
                  3335599*************.99******9615788999999**99986 PP

>> CoA_binding_2  CoA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0       1.7   1.9e+03      29      83 ..     192     219 ..     159     258 .. 0.56
   2 ?    6.1   0.0     0.014        15      54      88 ..     433     467 ..     418     481 .. 0.86
   3 ?    2.8   0.1      0.14   1.6e+02      27      71 ..     481     525 ..     475     530 .. 0.85

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 1.7
                    -EEEESSS-SEETTEES----T....T--EEEE-S-HHHHGGGHHHHHHH--SEE CS
  CoA_binding_2  29 pvvpVnpkeeeilgekvyaslaedpepvdlvdvftppeatpeivkealalgakav 83 
                     v++V  +++++l  + +++++e                            +  +
     EEA20164.1 192 AVIVVK-TKDSVLSYPTVETVQE--------------------------DSICKL 219
                    344442.2345555455555543..........................332222 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.014
                    .T--EEEE-S-HHHHGGGHHHHHHH--SEEEE-TT CS
  CoA_binding_2  54 epvdlvdvftppeatpeivkealalgakavwlqpg 88 
                     +vd+ +  + pe ++e++ +a+++g+k+++  +g
     EEA20164.1 433 PEVDITSAHRTPEYMAEYASKAASRGIKVIIAAAG 467
                    68999999**********************99888 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.14
                    T--EEEESSS-SEETTEES----T....T--EEEE-S-HHHHGGG CS
  CoA_binding_2  27 glpvvpVnpkeeeilgekvyaslaedpepvdlvdvftppeatpei 71 
                     lpv+ V  k+++++g+++  s+ + p  v +++v ++ ++ +++
     EEA20164.1 481 ALPVIGVPVKGSALDGVDSLYSIVQMPRGVPVATVGINNSINAAL 525
                    4899***99***************747999999999998877766 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.1   0.00017       0.2       4      69 ..      11      72 ..       8      88 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00017
                ETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHCEEEE--TT-HHHHHHHHHHHT-SEEE CS
   Epimerase  4 tGatGfiGsalvkallekgyevigldrlssasntarledlelveldltdrsalerlfkeeqpdavi 69
                +G+ G++G+ l++  ++ ++ev++ld   sa +++  ++ + + + + d++++++l k   +d+v 
  EEA20164.1 11 LGG-GQLGRMLTESANRLNIEVHVLDAA-SAPAKQISAHDSHTIGHFNDQESVQELAK--TCDVVT 72
                555.************************.5566666666688999**********999..788885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (573 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       534  (0.0297841); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              16  [number of targets reported over threshold]
# CPU time: 0.67u 0.32s 00:00:00.99 Elapsed: 00:00:00.50
# Mc/sec: 3419.00
//
Query:       EEA20165.1  [L=222]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
       0.23   11.7   4.3        1.5    9.1   4.3    2.3  1  Polyketide_cyc2  Polyketide cyclase / dehydrase and lipid tra


Domain annotation for each model (and alignments):
>> Polyketide_cyc2  Polyketide cyclase / dehydrase and lipid transport
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   4.3   8.3e-05       1.5      12      51 ..      32      69 ..      23     221 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 8.3e-05
                     S-HHHHHHHHTTTTGGGGT-TTEEEEECSESTSSSTTTEE CS
  Polyketide_cyc2 12 appekVwalvsdfenwprWhpevarveleggggpargveg 51
                      +  kV+  + d ++wp+W   v+ +++++++ +   +  
       EEA20165.1 32 SSSTKVFNTLVDVSTWPKWNRWVPYCTIRYQPTT--TSTC 69
                     57789*********************99985555..3322 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (222 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       356  (0.0198561); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.27s 00:00:00.69 Elapsed: 00:00:00.42
# Mc/sec: 1579.13
//
Query:       EEA20166.1  [L=708]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
      0.026   14.8   5.1        2.1    8.7   2.5    3.1  2  DUF5082         Domain of unknown function (DUF5082)


Domain annotation for each model (and alignments):
>> DUF5082  Domain of unknown function (DUF5082)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   2.5   0.00011       2.1      21      89 ..      27      96 ..      17     134 .. 0.86
   2 ?    5.2   0.0    0.0013        24      13      51 ..     669     707 ..     658     708 .] 0.87

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00011
     DUF5082 21 aleekIerLkeaktklsdekeslkqkkkklekplnssesWkGkeennydgirs.nlessyqtyvdkldel 89
                a + +I rL  a ++l++  esl +++k+      ++  + G++++++ ++++ +  + yq++ d+ ++l
  EEA20166.1 27 AKQTQIMRLSLAQSTLDELVESLRNDQKARLRLGKHQTLYYGSKSQQFHSHLEsHRSELYQASADDQENL 96
                5689***************************************999999999878899999999999887 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0013
     DUF5082  13 aelrseiaaleekIerLkeaktklsdekeslkqkkkkle 51 
                  +l ++++ + ++++rLk++  +++  k++++++ + l+
  EEA20166.1 669 NSLVNQMDPTPSDLSRLKQMHARVQRMKKEIWDEDRRLR 707
                 678899999999*********************988775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (708 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1215  (0.0677673); expected 358.6 (0.02)
Passed bias filter:                      451  (0.0251548); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.77u 0.35s 00:00:01.12 Elapsed: 00:00:00.50
# Mc/sec: 4258.77
//
Query:       EEA20167.1  [L=709]
Description: YagE family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.1e-53  181.9   0.1    1.7e-53  181.3   0.1    1.3  1  DUF155      Uncharacterised ACR, YagE family COG1723
  ------ inclusion threshold ------
        0.2    9.9   3.4       0.29    9.4   3.4    1.1  1  CDC45       CDC45-like protein
        4.4    6.0   5.3        7.6    5.2   5.3    1.3  1  Presenilin  Presenilin
        6.9    7.3  12.3       0.53   10.9   3.5    2.6  3  Pex14_N     Peroxisomal membrane anchor protein (Pex14p) cons


Domain annotation for each model (and alignments):
>> DUF155  Uncharacterised ACR, YagE family COG1723
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  181.3   0.1   3.8e-57   1.7e-53       1     176 []     423     606 ..     423     606 .. 0.95

  Alignments for each domain:
  == domain 1  score: 181.3 bits;  conditional E-value: 3.8e-57
      DUF155   1 vfiFknGsvVfwgldeeeeknflnkllkflnees.......elpreeeqeteeleyvydeqsessrikgdvivlkskslleklaiShalaqSvkLdvlE 92 
                 +f+F++G+vVfw+++e++ek++l++l+   +           +  ee  etee+++ y++q +++r+++d+i+l+s++++ klaiSh++aqS+kL ++E
  EEA20167.1 423 MFVFSYGVVVFWNFTERQEKDILADLTFSSSGTGpqislatLPLAEEDFETEEFHFEYSTQISRPRVYNDMITLRSRDHMIKLAISHGIAQSTKLCFFE 521
                 6************************9977544449999998888888888************************************************* PP

      DUF155  93 esldellestekipkelakkgklklsrkellkktgellslrinlnlkselldtPdffWee.peleslyeavseyleikeRikiLn 176
                 e++++ +++ +++p++la +g+l ++r+e+++ +g+l+++r ++nl+s++ld+P+ffWe+ p+l +ly av+eyleik+Ri++Ln
  EEA20167.1 522 EAMSKEMTEAKDVPRRLAMTGTLGMKREEVFRILGRLFKSRVEVNLSSNMLDVPNFFWESePTLYPLYIAVREYLEIKPRIQVLN 606
                 *********************99***********************************666***********************9 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   3.4   6.4e-05      0.29     112     198 ..     323     400 ..     309     444 .. 0.37

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 6.4e-05
       CDC45 112 ieeeleeereayealeeeeesdeedeeeeeeddddeeeeeeeeedeedeeedeeeskkkrksksdeeeesddddersrkrrrse..psa 198
                 ie++   e+ +y++  + ee +        ++   ++++++e+e+++++++d++++++++ s++d++ +s+++++ s+ r+ ++  p++
  EEA20167.1 323 IERN---EQRDYHEEYYVEEHE--------HSVGGQGNQNNESEASDRNQNDHKSDSQDTASRTDNQPASSEQQTDSKPRQGHNppPTT 400
                 2221...111222222222221........11111111111111111111111111111111122222233333333333333321222 PP

>> Presenilin  Presenilin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   5.3    0.0017       7.6     253     297 ..     346     390 ..     316     445 .. 0.42

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.0017
  Presenilin 253 keeeseeesseksaqsseseeeseeesseaessaeesseekesee 297
                  + ++++es+ + +++++++++s++++s++++++++s+++++s++
  EEA20167.1 346 GQGNQNNESEASDRNQNDHKSDSQDTASRTDNQPASSEQQTDSKP 390
                 111111111111111111111111111111111111111111111 PP

>> Pex14_N  Peroxisomal membrane anchor protein (Pex14p) conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.5     0.091   4.1e+02      89     143 ..      33      87 ..       3      92 .. 0.44
   2 ?   -3.4   0.0         3   1.3e+04     107     128 ..     235     256 ..     222     271 .. 0.70
   3 ?   10.9   3.5   0.00012      0.53      37     124 ..     321     409 ..     318     436 .. 0.29

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.091
     Pex14_N  89 spspsppaqqqqqqyrpPivtypefltkppkppppPlrtwrdllitatalaglga 143
                 +p++   +  +  qy + i  +++    +++p+  P+ +++    +++a +g++a
  EEA20167.1  33 PPATRLITVDNVLQYASDIPSMQQRRPMQQRPQMRPRSRLSASTGIIGASSGASA 87 
                 1111122222223333444444333333445555566555555555555555555 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 3
     Pex14_N 107 ivtypefltkppkppppPlrtw 128
                    y e l k+++++++P++t 
  EEA20167.1 235 AKSYAERLPKARRAEKLPRVTA 256
                 4568888888888888888854 PP

  == domain 3  score: 10.9 bits;  conditional E-value: 0.00012
     Pex14_N  37 eEIeeaLkraereeease..sa.vaassaseqaqeesasssatpqpqaasqtsqsspspsppaqqqqqqy.......rpPivtypefltkppkppppP 124
                 eEIe+  +r+ +ee+  e  +  v +++++   ++es+ s+++++  ++ ++ ++s++ ++pa+++qq+         pP +t       ++ +p + 
  EEA20167.1 321 EEIERNEQRDYHEEYYVEehEHsVGGQGNQ---NNESEASDRNQNDHKSDSQDTASRTDNQPASSEQQTDskprqghNPPPTTS------SSTTPTTN 409
                 555555555333333322321122222222...111111111111111111111111111222222222221222223333332......22222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (709 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1223  (0.0682135); expected 358.6 (0.02)
Passed bias filter:                      679  (0.0378716); expected 358.6 (0.02)
Passed Vit filter:                        98  (0.005466); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.79u 0.35s 00:00:01.14 Elapsed: 00:00:00.51
# Mc/sec: 4158.89
//
Query:       EEA20168.1  [L=441]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.4e-19   67.8  27.4    3.5e-05   24.0   1.7    4.4  4  zf-C2H2          Zinc finger, C2H2 type
    6.9e-17   61.0  23.9    1.4e-06   28.5   1.5    5.4  5  zf-H2C2_2        Zinc-finger double domain
    2.9e-10   40.1  25.1      0.004   17.9   1.3    4.4  4  zf-C2H2_4        C2H2-type zinc finger
    1.3e-05   25.3   2.3       0.87    9.9   0.1    4.1  4  zf-C2H2_jaz      Zinc-finger double-stranded RNA-binding
    0.00052   20.3  12.1      0.044   14.2   0.2    3.9  4  zf-met           Zinc-finger of C2H2 type
     0.0088   16.7  10.5       0.14   12.8   0.6    3.2  3  FOXP-CC          FOXP coiled-coil domain
  ------ inclusion threshold ------
      0.015   15.4   0.4        2.5    8.2   0.0    2.2  2  zf-C2H2_aberr    Aberrant zinc-finger
      0.019   14.7   0.8      0.019   14.7   0.8    3.2  3  zf-C2H2_11       zinc-finger C2H2-type
      0.057   13.0   1.4        4.6    6.9   0.0    2.9  3  zf-MYST          MYST family zinc finger domain
       0.15   11.7   2.2        1.1    8.9   0.2    2.7  2  zf_UBZ           Ubiquitin-Binding Zinc Finger
       0.32   11.2   2.1         16    5.7   0.1    2.3  2  Yippee-Mis18     Yippee zinc-binding/DNA-binding /Mis18, cent
       0.98    9.7   4.7         17    5.7   0.0    3.0  3  LIM              LIM domain
        1.3    9.3   5.8        1.1    9.6   0.2    2.7  3  C1_4             TFIIH C1-like domain
        9.3    4.8   8.2       0.68    8.6   0.2    2.0  2  DUF4764          Domain of unknown function (DUF4764)


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   1.8   5.5e-07    0.0007       1      23 []     118     140 ..     118     140 .. 0.97
   2 !   18.3   0.1   1.7e-06    0.0022       2      23 .]     147     170 ..     146     170 .. 0.92
   3 !   24.0   1.7   2.8e-08   3.5e-05       1      23 []     176     198 ..     176     198 .. 0.96
   4 !   19.5   4.8   7.6e-07   0.00097       1      23 []     204     228 ..     204     228 .. 0.98

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 5.5e-07
                 EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirtH 23 
                 + C+ C k F r+s+L rH r+H
  EEA20168.1 118 FHCSTCQKGFARRSDLARHERIH 140
                 78*******************99 PP

  == domain 2  score: 18.3 bits;  conditional E-value: 1.7e-06
                 EET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2   2 kCp..dCgksFkrksnLkrHirtH 23 
                  C+  +Cgk F ++s L++H r+H
  EEA20168.1 147 ACDwpGCGKQFIQRSALTVHARVH 170
                 58888*****************99 PP

  == domain 3  score: 24.0 bits;  conditional E-value: 2.8e-08
                 EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirtH 23 
                 + C+ Cgk+F+++s+L rH+r+H
  EEA20168.1 176 HMCERCGKPFSDSSSLARHRRIH 198
                 67********************9 PP

  == domain 4  score: 19.5 bits;  conditional E-value: 7.6e-07
                 EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirtH 23 
                 ykCp   C k+F+r+  L+rH++ H
  EEA20168.1 204 YKCPyaNCQKTFTRRTTLTRHQNHH 228
                 9**********************99 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.1     0.015        20      13      25 ..     116     128 ..      99     129 .. 0.81
   2 !   16.7   0.0   5.6e-06    0.0072       1      24 [.     132     157 ..     132     159 .. 0.93
   3 !   22.2   0.7     1e-07   0.00013       1      22 [.     162     183 ..     162     186 .. 0.91
   4 !   28.5   1.5   1.1e-09   1.4e-06       1      26 []     190     217 ..     190     217 .. 0.93
   5 ?    0.9   1.6      0.56   7.2e+02       2      11 ..     221     230 ..     220     231 .. 0.92

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.015
   zf-H2C2_2  13 kpyeCplCdkaFk 25 
                 + ++C+ C k F+
  EEA20168.1 116 RVFHCSTCQKGFA 128
                 449*********8 PP

  == domain 2  score: 16.7 bits;  conditional E-value: 5.6e-06
   zf-H2C2_2   1 nLrrHirkHtgekpyeCp..lCdkaF 24 
                 +L rH r H g +p+ C+   C+k F
  EEA20168.1 132 DLARHERIHSGIRPHACDwpGCGKQF 157
                 589****************99***99 PP

  == domain 3  score: 22.2 bits;  conditional E-value: 1e-07
   zf-H2C2_2   1 nLrrHirkHtgekpyeCplCdk 22 
                 +L+ H r+Htgekp+ C+ C+k
  EEA20168.1 162 ALTVHARVHTGEKPHMCERCGK 183
                 6899****************99 PP

  == domain 4  score: 28.5 bits;  conditional E-value: 1.1e-09
   zf-H2C2_2   1 nLrrHirkHtgekpyeCp..lCdkaFkt 26 
                 +L rH r H g++py+Cp   C k+F++
  EEA20168.1 190 SLARHRRIHSGKRPYKCPyaNCQKTFTR 217
                 589***************999*****85 PP

  == domain 5  score: 0.9 bits;  conditional E-value: 0.56
   zf-H2C2_2   2 LrrHirkHtg 11 
                 L+rH+  Htg
  EEA20168.1 221 LTRHQNHHTG 230
                 89*******8 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   1.4     8e-05       0.1       1      23 [.     118     140 ..     118     141 .. 0.95
   2 !    8.0   0.2    0.0047         6       2      23 ..     147     170 ..     146     171 .. 0.87
   3 !   17.9   1.3   3.1e-06     0.004       1      23 [.     176     198 ..     176     199 .. 0.93
   4 !   14.9   2.9   2.8e-05     0.036       1      23 [.     204     228 ..     204     229 .. 0.91

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 8e-05
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlkth 23 
                 f C+ C+k F ++++L rH + h
  EEA20168.1 118 FHCSTCQKGFARRSDLARHERIH 140
                 89******************999 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0047
   zf-C2H2_4   2 kCpi..CgksFsskkaLlrHlkth 23 
                  C++  Cgk F  ++aL  H + h
  EEA20168.1 147 ACDWpgCGKQFIQRSALTVHARVH 170
                 577777**************9988 PP

  == domain 3  score: 17.9 bits;  conditional E-value: 3.1e-06
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlkth 23 
                 + C+ Cgk+Fs++++L rH + h
  EEA20168.1 176 HMCERCGKPFSDSSSLARHRRIH 198
                 57******************999 PP

  == domain 4  score: 14.9 bits;  conditional E-value: 2.8e-05
   zf-C2H2_4   1 fkCpi..CgksFsskkaLlrHlkth 23 
                 +kCp+  C+k+F+++++L rH + h
  EEA20168.1 204 YKCPYanCQKTFTRRTTLTRHQNHH 228
                 89*******************6655 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.9   0.1   0.00068      0.87       3      22 ..     119     138 ..     117     138 .. 0.91
   2 ?    0.1   0.0      0.85   1.1e+03       7      20 ..     153     166 ..     153     166 .. 0.89
   3 !    6.3   0.0    0.0092        12       2      21 ..     176     195 ..     175     196 .. 0.91
   4 ?    5.2   0.1     0.022        28       7      22 ..     211     226 ..     209     226 .. 0.94

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00068
                  BBTTTTBBBSSHHHHHCCTT CS
  zf-C2H2_jaz   3 YCvlCdKyFksenaldnHlk 22 
                   C +C+K F   ++l  H++
   EEA20168.1 119 HCSTCQKGFARRSDLARHER 138
                  5*****************86 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.85
                  TTBBBSSHHHHHCC CS
  zf-C2H2_jaz   7 CdKyFksenaldnH 20 
                  C K+F+  +al  H
   EEA20168.1 153 CGKQFIQRSALTVH 166
                  9*****99999888 PP

  == domain 3  score: 6.3 bits;  conditional E-value: 0.0092
                  CBBTTTTBBBSSHHHHHCCT CS
  zf-C2H2_jaz   2 fYCvlCdKyFksenaldnHl 21 
                  + C+ C K F+++++l  H 
   EEA20168.1 176 HMCERCGKPFSDSSSLARHR 195
                  78999*************97 PP

  == domain 4  score: 5.2 bits;  conditional E-value: 0.022
                  TTBBBSSHHHHHCCTT CS
  zf-C2H2_jaz   7 CdKyFksenaldnHlk 22 
                  C+K+F    +l  H++
   EEA20168.1 211 CQKTFTRRTTLTRHQN 226
                  **************87 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.2   3.4e-05     0.044       1      21 [.     118     138 ..     118     140 .. 0.94
   2 ?   -2.8   0.0       7.7   9.9e+03       6      19 ..     153     166 ..     153     168 .. 0.81
   3 ?    6.0   0.2     0.013        17       2      19 ..     177     194 ..     176     198 .. 0.91
   4 ?    6.3   0.9      0.01        13       6      21 ..     211     226 ..     211     229 .. 0.91

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 3.4e-05
      zf-met   1 fyCelCnvtfnsesqlksHlq 21 
                 f+C+ C++ f  +s+l  H +
  EEA20168.1 118 FHCSTCQKGFARRSDLARHER 138
                 89*****************87 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 7.7
      zf-met   6 CnvtfnsesqlksH 19 
                 C ++f  +s+l  H
  EEA20168.1 153 CGKQFIQRSALTVH 166
                 99999988888766 PP

  == domain 3  score: 6.0 bits;  conditional E-value: 0.013
      zf-met   2 yCelCnvtfnsesqlksH 19 
                 +Ce C + f++ s+l  H
  EEA20168.1 177 MCERCGKPFSDSSSLARH 194
                 6***************99 PP

  == domain 4  score: 6.3 bits;  conditional E-value: 0.01
      zf-met   6 CnvtfnsesqlksHlq 21 
                 C++tf+ +++l  H +
  EEA20168.1 211 CQKTFTRRTTLTRHQN 226
                 ************9987 PP

>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.8   0.6   0.00011      0.14       6      27 ..     147     168 ..     144     181 .. 0.85
   2 ?   -1.3   0.0       2.7   3.5e+03      12      26 ..     181     195 ..     174     199 .. 0.87
   3 !    9.4   0.2    0.0013       1.6       7      42 ..     206     241 ..     203     248 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 0.00011
     FOXP-CC   6 vCkWPgCekvledveeflkhln 27 
                  C+WPgC k + + ++++ h++
  EEA20168.1 147 ACDWPGCGKQFIQRSALTVHAR 168
                 7**************9999975 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 2.7
     FOXP-CC  12 Cekvledveeflkhl 26 
                 C k ++d++++ +h 
  EEA20168.1 181 CGKPFSDSSSLARHR 195
                 999********9995 PP

  == domain 3  score: 9.4 bits;  conditional E-value: 0.0013
     FOXP-CC   7 CkWPgCekvledveeflkhlnseHalddkstaqlrv 42 
                 C   +C+k ++  +++++h n++  + ++++aq+++
  EEA20168.1 206 CPYANCQKTFTRRTTLTRHQNHHTGTIEEAAAQTEA 241
                 8899*****************99999999***9986 PP

>> zf-C2H2_aberr  Aberrant zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   0.1     0.014        18     142     164 ..     147     169 ..     138     180 .. 0.86
   2 ?    8.2   0.0     0.002       2.5       1      25 [.     204     228 ..     200     249 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.014
  zf-C2H2_aberr 142 yCripGCgkrfkslmaYkYhckk 164
                     C  pGCgk+f +  a   h++ 
     EEA20168.1 147 ACDWPGCGKQFIQRSALTVHARV 169
                    5999********99999999865 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.002
  zf-C2H2_aberr   1 ykClykaCdlkyssvlglrrhlvey 25 
                    ykC+y +C+ ++ +  +l rh  + 
     EEA20168.1 204 YKCPYANCQKTFTRRTTLTRHQNHH 228
                    9**********99999999997664 PP

>> zf-C2H2_11  zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   1.0      0.26   3.3e+02       6      26 ..     119     139 ..     117     140 .. 0.90
   2 ?   14.7   0.8   1.5e-05     0.019       6      26 ..     177     197 ..     174     198 .. 0.93
   3 ?   -0.1   0.1      0.63   8.1e+02       9      23 ..     210     224 ..     205     226 .. 0.89

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.26
  zf-C2H2_11   6 qCleCGlcftSqlsLsRHlfI 26 
                  C  C   f+    L RH +I
  EEA20168.1 119 HCSTCQKGFARRSDLARHERI 139
                 69999999**********988 PP

  == domain 2  score: 14.7 bits;  conditional E-value: 1.5e-05
  zf-C2H2_11   6 qCleCGlcftSqlsLsRHlfI 26 
                  C  CG  f+ + sL RH++I
  EEA20168.1 177 MCERCGKPFSDSSSLARHRRI 197
                 5*******************9 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.63
  zf-C2H2_11   9 eCGlcftSqlsLsRH 23 
                  C   ft    L RH
  EEA20168.1 210 NCQKTFTRRTTLTRH 224
                 68899********** PP

>> zf-MYST  MYST family zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0     0.033        42      29      53 ..     114     138 ..      98     139 .. 0.84
   2 ?    6.9   0.0    0.0036       4.6      33      53 ..     176     196 ..     168     197 .. 0.90
   3 ?   -2.1   0.5       2.3     3e+03      38      53 ..     211     226 ..     204     227 .. 0.79

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.033
     zf-MYST  29 kekLyvCefClkYmksakelerHkk 53 
                  ++++ C  C k ++ +++l rH +
  EEA20168.1 114 APRVFHCSTCQKGFARRSDLARHER 138
                 5689*******************86 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0036
     zf-MYST  33 yvCefClkYmksakelerHkk 53 
                  +Ce+C k ++++++l rH++
  EEA20168.1 176 HMCERCGKPFSDSSSLARHRR 196
                 58*****************97 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 2.3
     zf-MYST  38 ClkYmksakelerHkk 53 
                 C k ++ +++l+rH++
  EEA20168.1 211 CQKTFTRRTTLTRHQN 226
                 7777889999999986 PP

>> zf_UBZ  Ubiquitin-Binding Zinc Finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.1      0.16   2.1e+02       3      20 ..     118     136 ..     117     137 .. 0.76
   2 ?    8.9   0.2   0.00088       1.1       5      19 ..     178     193 ..     175     195 .. 0.81

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.16
      zf_UBZ   3 ylCerCgkeipes.elqEH 20 
                 + C+ C+k +    +l+ H
  EEA20168.1 118 FHCSTCQKGFARRsDLARH 136
                 67******98876666666 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.00088
      zf_UBZ   5 CerCgkeipes.elqE 19 
                 CerCgk++++s +l+ 
  EEA20168.1 178 CERCGKPFSDSsSLAR 193
                 *********9866655 PP

>> Yippee-Mis18  Yippee zinc-binding/DNA-binding /Mis18, centromere assembly
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   0.2     0.018        23       2      24 ..     117     139 ..     116     176 .. 0.78
   2 ?    5.7   0.1     0.013        16       4      25 ..     177     209 ..     174     245 .. 0.67

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.018
                   EEEETTTS-EEEECCCEEEEECC CS
  Yippee-Mis18   2 vfqCkkCktilgdslqlvsegra 24 
                   vf+C++C++ ++  ++l  ++r 
    EEA20168.1 117 VFHCSTCQKGFARRSDLARHERI 139
                   8**********999999987664 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.013
                   EETTTS-EEEECCCEEEEECC...........C CS
  Yippee-Mis18   4 qCkkCktilgdslqlvsegra...........l 25 
                    C++C ++++ds++l  ++r            +
    EEA20168.1 177 MCERCGKPFSDSSSLARHRRIhsgkrpykcpyA 209
                   6**************996665445555555441 PP

>> LIM  LIM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.0     0.013        17      27      41 ..     118     133 ..     115     141 .. 0.77
   2 ?    3.5   0.1     0.068        87      27      40 ..     176     189 ..     151     204 .. 0.66
   3 ?    3.1   1.0     0.089   1.1e+02       1      40 [.     178     219 ..     178     229 .. 0.66

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.013
                 SB-TTT-SB-CTT..C CS
         LIM  27 FtCsdCqkeLkegs.f 41 
                 F Cs+Cqk ++++s +
  EEA20168.1 118 FHCSTCQKGFARRSdL 133
                 99******99988754 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.068
                 SB-TTT-SB-CTT. CS
         LIM  27 FtCsdCqkeLkegs 40 
                  +C+ C+k++++ s
  EEA20168.1 176 HMCERCGKPFSDSS 189
                 57999999988876 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.089
                 -TTT--BE-TTTEEEEETTEEEET..TTSB-..TTT-SB-CTT. CS
         LIM   1 CagCnkkiadrelvlkaldkvwHe..eCFtC..sdCqkeLkegs 40 
                 C++C+k+++d+  +  a+ ++ H   + ++C  ++Cqk++++++
  EEA20168.1 178 CERCGKPFSDSSSL--ARHRRIHSgkRPYKCpyANCQKTFTRRT 219
                 88888888877777..6777777422567775567888777776 PP

>> C1_4  TFIIH C1-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.2   0.00085       1.1      21      49 ..     113     141 ..      99     154 .. 0.84
   2 ?    0.4   0.3       0.6   7.7e+02       4      35 ..     152     185 ..     147     200 .. 0.72
   3 ?    0.6   1.2      0.53   6.8e+02       2      35 ..     178     215 ..     177     229 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00085
        C1_4  21 ltssryrCekCkndFCiDCDvFiHesLHn 49 
                  +  +++C +C++ F    D+  He +H+
  EEA20168.1 113 PAPRVFHCSTCQKGFARRSDLARHERIHS 141
                 55679**********************97 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.6
        C1_4   4 gCqkkfpklakkkkdee..ltssryrCekCkndF 35 
                 gC k+f +    + + +  + +  + Ce+C + F
  EEA20168.1 152 GCGKQFIQRSALTVHARvhTGEKPHMCERCGKPF 185
                 6777777766665554433556778899998776 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.53
        C1_4   2 CygCqkkfpklakkkkdee..ltssryrCe..kCkndF 35 
                 C  C k f  + + + +++  + +  y+C+  +C+++F
  EEA20168.1 178 CERCGKPFSDSSSLARHRRihSGKRPYKCPyaNCQKTF 215
                 77787877776665554443366778999744788887 PP

>> DUF4764  Domain of unknown function (DUF4764)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.2   0.00053      0.68     188     211 ..     115     138 ..     111     149 .. 0.91
   2 ?   -1.5   3.3       0.6   7.7e+02     191     266 ..     176     253 ..     159     277 .. 0.60

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00053
     DUF4764 188 PktFkCqtCeKSYIGkGGLARHyK 211
                 P+ F+C tC+K +  +  LARH +
  EEA20168.1 115 PRVFHCSTCQKGFARRSDLARHER 138
                 9*********************76 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.6
     DUF4764 191 FkCqtCeKSYIGkGGLARHyKLNPgHgelepevllsekan.gsvtlg.kveertisltspelstpallseegaesara 266
                   C+ C+K +     LARH ++  g    +     ++k     +tl+ +++++t ++++  + t a l+++ ++sara
  EEA20168.1 176 HMCERCGKPFSDSSSLARHRRIHSGKRPYKCPYANCQKTFtRRTTLTrHQNHHTGTIEEAAAQTEASLRQNREKSARA 253
                 469999999999999999999866654333333333333212222220233334444444444444444444555443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (441 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       668  (0.0372581); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                        21  (0.00117129); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.64u 0.31s 00:00:00.95 Elapsed: 00:00:00.53
# Mc/sec: 2511.89
//
Query:       EEA20169.1  [L=331]
Description: 3-demethylubiquinone-9 3-methyltransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.6e-17   63.1   0.0    4.1e-17   62.5   0.0    1.2  1  Methyltransf_23  Methyltransferase domain
    1.5e-13   51.2   0.0    3.4e-13   50.0   0.0    1.6  1  Methyltransf_11  Methyltransferase domain
      1e-11   45.4   0.0    3.5e-11   43.7   0.0    1.8  1  Methyltransf_25  Methyltransferase domain
    4.1e-11   43.5   0.0    8.9e-11   42.4   0.0    1.6  1  Methyltransf_12  Methyltransferase domain
    1.9e-08   34.2   0.0    2.7e-08   33.7   0.0    1.2  1  Methyltransf_31  Methyltransferase domain
     0.0011   18.3   0.0       0.14   11.4   0.0    2.1  2  CMAS             Mycolic acid cyclopropane synthetase
  ------ inclusion threshold ------
      0.024   14.1   0.0        4.2    6.8   0.0    2.1  2  CheR             CheR methyltransferase, SAM binding domain
      0.086   12.2   0.0       0.12   11.6   0.0    1.2  1  Ubie_methyltran  ubiE/COQ5 methyltransferase family


Domain annotation for each model (and alignments):
>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.5   0.0   1.8e-20   4.1e-17      19     156 ..      96     274 ..      80     276 .. 0.69

  Alignments for each domain:
  == domain 1  score: 62.5 bits;  conditional E-value: 1.8e-20
  Methyltransf_23  19 klraggrvLdiGcGtGillevlre................ngfsvtgvDlspeaveiae................kakkaqkdqfdeqeaae.. 78 
                      + r+g r+Ld+GcG Gi++e+l++                +  s++++D+s  +++ia+                                +  
       EEA20169.1  96 RSRPGLRYLDVGCGGGIFAESLARtlpssksasaglhprtKARSIVAIDPSTSLIKIARdhasndpavfehlqsgA---------------Fsy 174
                      578888****************886888888887777653334***************954444444333332220...............122 PP

  Methyltransf_23  79 ............pqgkfdlIvlrevlehvpd..ppellrqiatllkpgGylllseplasl...kedrllldwlyl...vpagrhi..sffsars 150
                                   ++ fd+I+l+ev+ehv++    + l++  +ll pgG+l+ s++++       ++++ + +++   vp g+h   +f +a +
       EEA20169.1 175 enttieslsqshGDKLFDVITLFEVIEHVDPhtSSSFLTHCLKLLQPGGWLIGSTIARTIpsfIVNKMVAEAPWPigvVPWGTHEwsKFVNAGE 268
                      233333333333666***************734569*******************998775442566655544433333333333337777777 PP

  Methyltransf_23 151 lkelle 156
                      l+ ++e
       EEA20169.1 269 LRGWVE 274
                      777766 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.0   0.0   1.5e-16   3.4e-13       1      95 [.     104     226 ..     104     227 .. 0.90

  Alignments for each domain:
  == domain 1  score: 50.0 bits;  conditional E-value: 1.5e-16
                      EEET-TTSHHHHHHH..........HTT.......SEEEEEES-HHHHHHHHHHCCHHT-........EEEETTEECCCT..SS-TT-EEEEEE CS
  Methyltransf_11   1 LdvGcGtGrlaeala..........krg.......arvvgvDlskemlklakekaseegl........kvefvvadaekl..pfednsfDlvvs 67 
                      LdvGcG+G++ae la            g       +++v++D+s+ ++k+a+++as+++          +++   ++e+l     d+ fD++++
       EEA20169.1 104 LDVGCGGGIFAESLArtlpssksasA-GlhprtkaRSIVAIDPSTSLIKIARDHASNDPAvfehlqsgAFSYENTTIESLsqSHGDKLFDVITL 196
                      8**************99988887750.255555689**********************999999999988899999999853499********* PP

                      ES-CCC-..CCHHHHHHHHHHHEEEEEEEE CS
  Methyltransf_11  68 sevlhhv..edpekalkeiaRvLkpgGllv 95 
                      +ev++hv  +  +++l  + ++L+pgG+l+
       EEA20169.1 197 FEVIEHVdpHTSSSFLTHCLKLLQPGGWLI 226
                      *******999*****************997 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.7   0.0   1.6e-14   3.5e-11       2      97 .]     104     223 ..     104     223 .. 0.86

  Alignments for each domain:
  == domain 1  score: 43.7 bits;  conditional E-value: 1.6e-14
                      EEET-TTSHHHHHHHCT..............STSSEEEEEESSHHHHHHHHHHHHHTTT........TEEEEESBCCGBSS..STTTEEEEEEE CS
  Methyltransf_25   2 LdlGcGtGrltlalakr..............lgkakvtgvDiseemleaareraeeegl........nvefvqgdaedlpf..edgsfDlvvss 71 
                      Ld+GcG G +++ la+                ++ +++++D+s +++++ar +a+++ +         +++++  +e+l++   d+ fD+++++
       EEA20169.1 104 LDVGCGGGIFAESLARTlpssksasaglhprTKARSIVAIDPSTSLIKIARDHASNDPAvfehlqsgAFSYENTTIESLSQshGDKLFDVITLF 197
                      8****************888888887754432499*******************984445555577788889999999985337889******8 PP

                      STGGGSSHHHHHHHHHHHHHHEEEEE CS
  Methyltransf_25  72 galhhlsdedlekalkeiarvLkpgG 97 
                       +++h++++    +l ++ ++L+pgG
       EEA20169.1 198 EVIEHVDPHTSSSFLTHCLKLLQPGG 223
                      77***********************9 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.4   0.0     4e-14   8.9e-11       1      99 []     104     225 ..     104     225 .. 0.81

  Alignments for each domain:
  == domain 1  score: 42.4 bits;  conditional E-value: 4e-14
  Methyltransf_12   1 LeiGcGtGsllrallekl..............pdieytgvDispsaiedakeklakrennnnnnvelealdlldldgg........ssfDlvva 72 
                      L++GcG G +++ l++ l              +  +++++D+s+s i+ a+ + + +++  +++++  a + +++  +        + fD++++
       EEA20169.1 104 LDVGCGGGIFAESLARTLpssksasaglhprtKARSIVAIDPSTSLIKIARDHAS-NDPAVFEHLQSGAFSYENTTIEslsqshgdKLFDVITL 196
                      8******************************8888999*********55555544.444455555555544444444466666888******** PP

  Methyltransf_12  73 snvlhhl..kdirevldnirklLkpgGrl 99 
                      ++v++h+   +  ++l ++ klL pgG+l
       EEA20169.1 197 FEVIEHVdpHTSSSFLTHCLKLLQPGGWL 225
                      *******955555**************97 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.7   0.0   1.2e-11   2.7e-08       3     113 ..      99     231 ..      97     267 .. 0.74

  Alignments for each domain:
  == domain 1  score: 33.7 bits;  conditional E-value: 1.2e-11
  Methyltransf_31   3 kglrvlDlGCGtGeltfelae....elgpkae..............vvGiDiseeaielArenaqklgldnveFeqgdieelekl.led..... 72 
                       glr+lD+GCG G ++  la+          +              +v iD s   i+ Ar +a++     +e  q+ +++ e++ +e      
       EEA20169.1  99 PGLRYLDVGCGGGIFAESLARtlpsS-----KsasaglhprtkarsIVAIDPSTSLIKIARDHASNDPA-VFEHLQSGAFSYENTtIESlsqsh 186
                      6899****************744440.....334566667777889****************7664333.455555555554444444445555 PP

  Methyltransf_31  73 ..ekfDlilsnevl..naladpdkileeiervlkpggilliedpr 113
                        + fD+i+ +ev+   +   + ++l    ++l+pgg l+ +++ 
       EEA20169.1 187 gdKLFDVITLFEVIehVDPHTSSSFLTHCLKLLQPGGWLIGSTIA 231
                      55************7444456678899999*******99987776 PP

>> CMAS  Mycolic acid cyclopropane synthetase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.8   0.0    0.0066        15      61      80 ..      98     117 ..      94     124 .. 0.82
   2 !   11.4   0.0   6.4e-05      0.14     125     173 ..     188     236 ..     163     263 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0066
                 -TT-EEEEES-TTSHHHHHH CS
        CMAS  61 kpGmtlLdiGcGWGslvrra 80 
                 +pG + Ld+GcG G  +   
  EEA20169.1  98 RPGLRYLDVGCGGGIFAESL 117
                 6999********88776655 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 6.4e-05
                 ----SEEEEES-GGGTSGGGHHHHHHHHHHHS-TT-EEEEEEEEE--HH CS
        CMAS 125 dekvdrvvsvgafehvgkenydtffkklkkllkedGllllhtitslhkk 173
                 d+ +d +  ++++ehv  +    f  ++ kll+++G l+  ti ++ ++
  EEA20169.1 188 DKLFDVITLFEVIEHVDPHTSSSFLTHCLKLLQPGGWLIGSTIARTIPS 236
                 6689***********************************9999887655 PP

>> CheR  CheR methyltransferase, SAM binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.0    0.0019       4.2      13      82 ..      80     155 ..      72     171 .. 0.74
   2 ?    5.3   0.0    0.0053        12     130     172 ..     184     226 ..     165     229 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0019
                 HHHHHCCH.HHHHHHHTSSS.EEEEEES-TTTHHHHHHHHHHHCHSTTTSSS.....-EEEEEEESSCHHHHHHHH CS
        CheR  13 eelekevlepllakaknekr.vriwsagcssGeEpYslAmllketlpkaakl.....kvkilAtDidlkvlekAka 82 
                 +++++ + e++ +   ++++ +r + +gc+ G  + slA +l +   + a+l       +i+A+D +++ ++ A+ 
  EEA20169.1  80 DFIASCISESEPQTTGRSRPgLRYLDVGCGGGIFAESLARTLPSSKSASAGLhprtkARSIVAIDPSTSLIKIARD 155
                 55666667666666655544599*******************885544443322233568************9996 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0053
                 -SGGG--EEEEEE-SSGGGC-CHHHHHHHHHHHCCEEEEEEEE CS
        CheR 130 kksvlgklDvifcrnvliYfdeetqekvlerfaeklkpgglLl 172
                 +++  + +Dvi++ +v+   d++t +  l +  + l+pgg L+
  EEA20169.1 184 QSHGDKLFDVITLFEVIEHVDPHTSSSFLTHCLKLLQPGGWLI 226
                 4555677*********************************985 PP

>> Ubie_methyltran  ubiE/COQ5 methyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   5.5e-05      0.12      45     150 ..      97     226 ..      73     245 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 5.5e-05
                      S--TTEEEEES-TT-HHHHHHHHHHHHHH.............EEEEEES-HHHHHHHHHHHHHHTSS.......TEEEEE--TTT-TTS..-T- CS
  Ubie_methyltran  45 vkrgakvlDvagGtgDlafklsdsvgekg.............kvvvlDinenmLkvgekklkeegki.......nieflqanaeeLpfe..dds 116
                      +++g + lDv +G g +a +l++++ ++               +v +D + +++k++++++ ++  +          + ++  e L  +  d+ 
       EEA20169.1  97 SRPGLRYLDVGCGGGIFAESLARTLPSSKsasaglhprtkarSIVAIDPSTSLIKIARDHASNDPAVfehlqsgAFSYENTTIESLSQShgDKL 190
                      466779*****************9988878999********99******************998766566655555566666677765522567 PP

                      EEEEEEES-GGG-S-..HHHHHHHHHHHEEEEEEEE CS
  Ubie_methyltran 117 fDvvtvsfGlrnvtD..klkaLkeayrvlkpGGrlv 150
                      fDv+t+   +  v     +  L +  + l+pGG l+
       EEA20169.1 191 FDVITLFEVIEHVDPhtSSSFLTHCLKLLQPGGWLI 226
                      888888555544432112345778888888888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (331 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       382  (0.0213063); expected 358.6 (0.02)
Passed bias filter:                      343  (0.019131); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.49u 0.30s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2227.31
//
Query:       EEA20170.1  [L=357]
Description: quinate utilisation oxidoreductase QutH [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.5e-22   78.1   0.1    1.6e-21   77.3   0.1    1.4  1  GFO_IDH_MocA   Oxidoreductase family, NAD-binding Rossmann fo
  ------ inclusion threshold ------
      0.026   15.2   0.0       0.05   14.3   0.0    1.4  1  NAD_binding_3  Homoserine dehydrogenase, NAD binding domain
       0.07   13.3   0.0       0.16   12.1   0.0    1.6  1  DapB_N         Dihydrodipicolinate reductase, N-terminus


Domain annotation for each model (and alignments):
>> GFO_IDH_MocA  Oxidoreductase family, NAD-binding Rossmann fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.3   0.1   2.7e-25   1.6e-21       2     120 .]      11     127 ..      10     127 .. 0.88

  Alignments for each domain:
  == domain 1  score: 77.3 bits;  conditional E-value: 2.7e-25
                   EEEEETTSHHHHHHHHHHHHTTTTEEEEEEECSSHHHHHHHHHHTTHEEESSHHHHHTCTTESEEEE-S-GGGHHHHHHHHHHTT-EEEEESSS-SS CS
  GFO_IDH_MocA   2 rvaiiGaGkigskhlrplnesqrleevvalldpdaeraeavaesfgveaysdleelladpeidavivatpngtheelakaaleagkhvllEKPlatt 98 
                    v++iG+G++g  h+ +++++ ++ ++++lld++ +      +  + +    lee la  ++d+v++ t++ th+++a+aa+e g hv++EKPla t
    EEA20170.1  11 TVVVIGIGQMGHSHALAYHHN-PGFKIIGLLDRRHPGKTFPDALKEYPLLFTLEEALA-LKPDVVSINTHTATHADYALAAMESGAHVFVEKPLAVT 105
                   69*************999998.************987765555555565556666666.48************************************ PP

                   HHHHHHHHHHHHHHTS-EEEE- CS
  GFO_IDH_MocA  99 veeakelvelaekkgklvsvgy 120
                   v++a+++v +a+++++++ +gy
    EEA20170.1 106 VSDAERVVSTAQRSNRKLVIGY 127
                   ****************999887 PP

>> NAD_binding_3  Homoserine dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   8.4e-06      0.05      21     114 ..      33     123 ..      16     125 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 8.4e-06
                    EEEEEEEEESSEEE-TTHHHHHT--CB---HHHHHHHHS-EEEEE-S--HHHHTTHHHHHHTTEEEE-S--CGGG-HHHHHHHTSSSTTS--.E CS
  NAD_binding_3  21 elelvavadrdsllskdrkallasealtldlddliahldpdvvVEcasseavaelvlkaLkagkdvvtankgaladealyeeLreaaeangaki 114
                    ++++ +++dr+    k     l++ +l   l++ +a l+pdvv  +++ +  a+++l+a+++g +v +    a++     e+ ++ a+++++k+
     EEA20170.1  33 GFKIIGLLDRR-HPGKTFPDALKEYPLLFTLEEALA-LKPDVVSINTHTATHADYALAAMESGAHVFVEKPLAVT-VSDAERVVSTAQRSNRKL 123
                    67888888888.666667778888899999999999.89***9999**********************9999999.777888888888888876 PP

>> DapB_N  Dihydrodipicolinate reductase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   2.7e-05      0.16       2      82 ..      11      84 ..      10      99 .. 0.67

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 2.7e-05
                EEEEETTTSHHHHHHHHHHHHSTTEEEEEEEETTCSTTTTTBHHHHSSSS--S-BEBSSHHHHHHH.-SEEEE-S-HHHHHH CS
      DapB_N  2 kvavvGasGrmGkevvkaveeaedlelvaavdrkeselegkdagellglgklgvavtddleevlek.advliDFTtpeavle 82
                 v+v+G+ G mG++ + a ++++++++ + +dr++    gk + ++      ++++  +lee+l+   dv+   T+ +   +
  EEA20170.1 11 TVVVIGI-GQMGHSHALAYHHNPGFKIIGLLDRRH---PGKTFPDA----LKEYPLLFTLEEALALkPDVVSINTHTATHAD 84
                69****9.*************************98...33333333....33455555555555554565544454444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (357 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       320  (0.0178482); expected 358.6 (0.02)
Passed bias filter:                      294  (0.016398); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 2376.96
//
Query:       EEA20171.1  [L=1080]
Description: sodium P-type ATPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-40  138.9  14.7    4.6e-33  114.2   0.1    3.6  4  E1-E2_ATPase     E1-E2 ATPase
    7.4e-30  104.0   3.2    7.5e-30  104.0   0.3    2.3  2  Cation_ATPase_C  Cation transporting ATPase, C-terminus
    5.9e-23   80.8   0.6    1.2e-22   79.7   0.0    1.9  2  Cation_ATPase    Cation transport ATPase (P-type)
    1.1e-15   58.6   0.4    3.8e-14   53.5   0.4    2.9  1  Hydrolase        haloacid dehalogenase-like hydrolase
    2.1e-13   49.8   0.0    6.1e-13   48.3   0.0    1.8  1  Cation_ATPase_N  Cation transporter/ATPase, N-terminus
    5.4e-05   23.1   1.2     0.0094   15.7   0.8    2.3  2  Hydrolase_3      haloacid dehalogenase-like hydrolase
  ------ inclusion threshold ------
       0.71    9.6   2.6          2    8.2   0.2    2.5  2  SurA_N_3         SurA N-terminal domain


Domain annotation for each model (and alignments):
>> E1-E2_ATPase  E1-E2 ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.4         2   5.1e+03     162     174 ..      73      85 ..      62     102 .. 0.49
   2 !  114.2   0.1   1.8e-36   4.6e-33       2     119 ..     125     268 ..     124     280 .. 0.94
   3 !   32.0   1.9   3.1e-11   7.9e-08     108     181 .]     296     367 ..     289     367 .. 0.92
   4 ?   -0.2   0.0      0.24   6.1e+02      92     134 ..     778     821 ..     773     844 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 2
                   THHHHHHHHHHHH CS
  E1-E2_ATPase 162 aLplavplalalg 174
                   a++l++ la+al+
    EEA20171.1  73 AMVLVLVLAMALA 85 
                   3333333333322 PP

  == domain 2  score: 114.2 bits;  conditional E-value: 1.8e-36
                   SS--EEEEE-TTS-EEEEGGG--TTSEEEEETT-B--SEEEEEEE-S.EEE-TTTS---S-EE-.........................G-TTEE-T CS
  E1-E2_ATPase   2 llpptakvirdgteeeidakelvpGDivllkagdrvpaDgrivegsa.evdesaLTGEslpvek.........................ekgdmvfs 72 
                   l++p+a vir+g++++i++ e+vpGDivl+k+gd+vpaD r+v+g + e+de +LTGE+ pv k                         ++ +mv+s
    EEA20171.1 125 LSSPSAMVIRNGQVDTIPSPEVVPGDIVLIKTGDTVPADLRLVDGMNlECDEKILTGEAIPVAKdaafdpkpsagegpsanaethigvgDRLNMVYS 221
                   7899*************************************************************************************9******* PP

                   T-EEEE-EEEEEEEE-TTTSTTTTTSTTS--------HHHHHHHHHH CS
  E1-E2_ATPase  73 GtvvvsgeakavVtatgedtelgkiarlveeakskktplqkkldklg 119
                   +++v++g+ k++V+ tg+ te+gkia++++ +k+ ++ +++   ++ 
    EEA20171.1 222 SSTVTKGRGKGIVVYTGMYTEIGKIAASMQGKKKHQKGTKNRSMSIK 268
                   ********************************988887777666655 PP

  == domain 3  score: 32.0 bits;  conditional E-value: 3.1e-11
                   --HHHHHHHHHHHHHHHHHHHHHHHHHHS-STTTSSTTHHHHHHHHHHHHHS-TTHHHHHHHHHHHHHHHHHHT CS
  E1-E2_ATPase 108 ktplqkkldklgkvlvpvvlliallvflialllgkslaeallralallvaaiPcaLplavplalalgarrlakk 181
                    tplq+kl+kl+  l+ +++++a++vf ++ ++  +  e  + a+++ +a+iP+ L++++++++++g++++ k+
    EEA20171.1 296 GTPLQRKLSKLAYSLFGLAIIFAIIVFGVNEFRVTN--EVAIYAISTGIAIIPESLIAVLTITMVVGMTQMHKR 367
                   59***************************9776665..89999****************************986 PP

  == domain 4  score: -0.2 bits;  conditional E-value: 0.24
                   STTTTTSTTS--------HHHHHHHHHHHH.HHHHHHHHHHHHH CS
  E1-E2_ATPase  92 telgkiarlveeakskktplqkkldklgkv.lvpvvlliallvf 134
                     ++ i+++vee ++   ++qk++  l +  ++ vvlli+ l+f
    EEA20171.1 778 DNFASIVNAVEEGRRMFDNIQKFVLHLLASnVAEVVLLIVGLAF 821
                   56889*****************9877666647888888877766 PP

>> Cation_ATPase_C  Cation transporting ATPase, C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.2      0.46   1.2e+03      91     177 ..     304     326 ..     234     366 .. 0.62
   2 !  104.0   0.3   2.9e-33   7.5e-30       3     180 ..     831    1034 ..     829    1036 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.46
  Cation_ATPase_C  91 qtmaFitlvlsqifnalnlrsrreslfkfsglfsnkllllaillslllqvlivyvpglnavfgtaplsleewlialllalvvllvde 177
                      + +a+  + l+ if +++                                                                   +e
       EEA20171.1 304 SKLAYSLFGLAIIFAIIVFGV----------------------------------------------------------------NE 326
                      444444444444444444443................................................................22 PP

  == domain 2  score: 104.0 bits;  conditional E-value: 2.9e-33
  Cation_ATPase_C    3 plsaiqiLwinLvtDllpalaLaleppekdimkrpPrkkkepliskkmlrriliqgllqalvtllvffltlllfgisekenkls........ 86  
                       pls++qiLwin++t ++pa+ L++e++++ +m+rpP ++k+ +++++++++++++g++++++tll+f +++++ g   ++  ++        
       EEA20171.1  831 PLSPLQILWINMLTSSFPAFGLGREKASACVMRRPPHNTKKGVFTWEVIVDMVVYGVIMGALTLLTFVIVIYGVGDGKPDLGSDcnrkdses 922 
                       9***********************************************************************76444444333366777777 PP

  Cation_ATPase_C   87 ...snyaqtmaFitlvlsqifnalnlrsrre...............slfkfsglfsnkllllaillslllqvlivyvpgln.avfgtaplsl 159 
                          + +a++++F  l ++ ++ a+ ++ +r+               ++ +f+ ++ nk+l++a+++ ++ ++  vy+pgln +vf+ + + +
       EEA20171.1  923 chvVFRARAAVFAELTWLILILAWEVKDLRNsmfnldplraeqegvKFPFFRDVWENKFLFWAVVIGAVSVFPAVYIPGLNtDVFKHRGI-G 1013
                       8889************************9998888888888887764445567779***********************983579*9999.8 PP

  Cation_ATPase_C  160 eewlialllalvvllvdelvK 180 
                       +ew ++++ +++ +l +e++K
       EEA20171.1 1014 WEWGLTFGAVIIFILGAEAWK 1034
                       899999999999999999998 PP

>> Cation_ATPase  Cation transport ATPase (P-type)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.3         3   7.6e+03       8      30 ..     440     462 ..     433     464 .. 0.79
   2 !   79.7   0.0   4.8e-26   1.2e-22       2      91 .]     476     566 ..     475     566 .. 0.92

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 3
  Cation_ATPase   8 fsensekdevkllGnktEsALlv 30 
                      e++ek +++ + +k E A+++
     EEA20171.1 440 AGEQNEKTQTNQTDSKEEDAITE 462
                    46788899999999999999875 PP

  == domain 2  score: 79.7 bits;  conditional E-value: 4.8e-26
  Cation_ATPase   2 lcNsaafsensekdevkllGnktEsALlvlaekl..gldteelreetkkvqeipFnssrKrmsvvlklepekkvrlyvKGApeiilkrCthv 91 
                    lcN a+++++++ ++++++G++tE+AL+v+a+++  g++t e + ++k+++e+pF+s  Krmsv+++   + + +++vKGA e+i++ Ct+v
     EEA20171.1 476 LCNLATVRYDNTASKWQTMGDPTEIALQVFAHRFgyGKKTLETEFKWKEIAEYPFDSAIKRMSVIYSK-GTDESMIFVKGAVERIIDLCTSV 566
                    8**99999**************************66666666677799*******************8.8*******************986 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.5   0.4   1.5e-17   3.8e-14       4     210 .]     386     754 ..     383     754 .. 0.78

  Alignments for each domain:
  == domain 1  score: 53.5 bits;  conditional E-value: 1.5e-17
                 EEEESBTTTBCHHHHHHHHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHETTTE....HHHHTHHHHHHHHHCHHHHHHHHHHHHHHCH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase   4 vvfDkdGTLttgepsvedvivsaalalaaaletgsehpigkalvaaakarsgaltgfatfigrg....ayaigkpewltaldippdlgaaigsaqsqgr 98 
                 ++ Dk+GTLt+g+++ ++++                   g   v++ ++ s +  g+ t+        ++ + +++  t +  ++  +++  ++ s g 
  EEA20171.1 386 ICSDKTGTLTQGQMVARKAWIPG---------------VGIYSVNQSDDASDPSRGYVTLDAASgdksEAGEQNEKTQTNQ--TDSKEEDAITEVSPGL 467
                 899***************99999...............3333456666666666666664333344444444444444444..3344444444444444 PP

                 HHHHH.............................................................................................. CS
                 xxxxx.............................................................................................. RF
   Hydrolase  99 tvall.............................................................................................. 103
                 +++ll                                                                                              
  EEA20171.1 468 ESFLLasslcnlatvrydntaskwqtmgdpteialqvfahrfgygkktletefkwkeiaeypfdsaikrmsviyskgtdesmifvkgaveriidlctsv 566
                 44444666666667777777777777777777777777778888888888888888888888888888888899999999999999************* PP

                 ........................................................TTHHHHHHHHHHTHHBHTTHHHHHHHHHHTTEEEEEEESSEHH CS
                 ........................................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase 104 ........................................................qaralavftiadplkvkpeaaeavasLkaagievvlltgdnpe 146
                                                                         + ++l++  + dp  ++ e+++a+ +   agi+v +ltgd+p+
  EEA20171.1 567 gignneqkmtpglkenilqqmkvladqglrvlavaqrpvpagyhkgdelaredvevDLNLLGLAGLYDP--PRLETKDAITECITAGIRVHMLTGDHPS 663
                 *******************************************************999***********..**************************** PP

                 HHHHHHHHTT....................GGGESEEEEHHCES.......STTTSHHHHHHHHHHHTSTGGGEEEEESSHHHHHHHHHTT CS
                 xxxxxxxxxx....................xxxxxxxxxxxxxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase 147 taeraanqlG....................ddyfdaviasdiet.......vakpspegkvaaireLqgkpeevamVGDgvnDaaalaaAg 210
                 ta ++a+++G                    +  fd+  + +i++       +a   p+ k + i  L  +    am GDgvnDa+ l+aA+
  EEA20171.1 664 TASAIAKEVGiiprhteslsaqeaaslvktAAEFDGMTEDEIDAmpslplvIARCAPNTKTRMIAALHRRRCFAAMTGDGVNDAPSLKAAD 754
                 ************9997666555555544444444444444444466666666666*************99999*****************8 PP

>> Cation_ATPase_N  Cation transporter/ATPase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.3   0.0   2.4e-16   6.1e-13       4      68 ..      20      84 ..      18      85 .. 0.97

  Alignments for each domain:
  == domain 1  score: 48.3 bits;  conditional E-value: 2.4e-16
  Cation_ATPase_N  4 lsleevlekLetdlenGLtqaeaaerlkkyGpNelkekkkkslwvkllkqftnplvilLlvaalv 68
                     ls++++   L+t+  +GL+++++   +++yG N+l+ +  ++++  l+kq++n +v++L+ a+++
       EEA20171.1 20 LSADDIVSYLDTNIDTGLSTQQVSSYQARYGHNKLSGEGGVTWYSVLVKQVSNAMVLVLVLAMAL 84
                     7899**********************************************************998 PP

>> Hydrolase_3  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.3   0.0    0.0055        14      19      54 ..     639     674 ..     635     681 .. 0.94
   2 !   15.7   0.8   3.7e-06    0.0094     209     254 ..     740     786 ..     730     787 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0055
                  HHHHHHHHHHHTTSEEEEE-SS-HHHHHHHHHHCCC CS
  Hydrolase_3  19 ktkeaikklkekgikvviATGRslravlpvleelgl 54 
                  +tk+ai +++ +gi v   TG ++++++ +++e+g+
   EEA20171.1 639 ETKDAITECITAGIRVHMLTGDHPSTASAIAKEVGI 674
                  79*******************************996 PP

  == domain 2  score: 15.7 bits;  conditional E-value: 3.7e-06
                  EESSGGGHHHHHHSSEEEEETTS-HHHHHHSSEEE--GGG.THHHHH CS
  Hydrolase_3 209 fGDgeNDieMLeaaglgvAmgnaseevkkaAdyvtksnne.dGVaka 254
                   GDg ND + L+aa++g+Amg +   v k A+ ++ + ++  ++++a
   EEA20171.1 740 TGDGVNDAPSLKAADVGIAMGMGGSDVAKSASDIVLTDDNfASIVNA 786
                  6********************98887777777766666665888776 PP

>> SurA_N_3  SurA N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   0.2    0.0008         2      16      62 ..      73     119 ..      66     132 .. 0.73
   2 ?    0.2   0.2      0.22   5.6e+02       8      37 ..     302     331 ..     298     347 .. 0.65

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0008
    SurA_N_3  16 illgliilaFvl.wGvgsylsgsgnsvakVngekIsraefqqayrrql 62 
                 +++++++la++l  Gv++y +g+  +++ V++  I + +  +a ++ +
  EEA20171.1  73 AMVLVLVLAMALaYGVSDYIEGGVITAVIVGNIVIGFYQEYRAEQK-M 119
                 4555566666666*********9988*********98776666555.3 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.22
    SurA_N_3   8 nakswiakillgl.iilaFvlwGvgsylsgs 37 
                 + ++ +a  l+gl ii+a +++Gv++++  +
  EEA20171.1 302 KLSK-LAYSLFGLaIIFAIIVFGVNEFRVTN 331
                 3333.4445555505555889***9987654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1080 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       943  (0.0525964); expected 358.6 (0.02)
Passed bias filter:                      657  (0.0366445); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.82u 0.30s 00:00:01.11 Elapsed: 00:00:00.43
# Mc/sec: 7496.32
//
Query:       EEA20172.1  [L=755]
Description: RING and UBP finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.9e-35  118.7   0.0    1.9e-34  117.8   0.0    1.4  1  BRAP2           BRCA1-associated protein 2
    4.8e-21   74.9   4.5    1.4e-20   73.4   4.5    1.8  1  zf-UBP          Zn-finger in ubiquitin-hydrolases and other p
    4.9e-08   33.2   9.5    4.9e-08   33.2   9.5    2.5  2  zf-RING_2       Ring finger domain
    1.5e-05   24.7   9.7    1.5e-05   24.7   9.7    2.2  1  zf-C3HC4_2      Zinc finger, C3HC4 type (RING finger)
    0.00044   20.1   5.1    0.00044   20.1   5.1    2.3  2  zf-C3HC4_3      Zinc finger, C3HC4 type (RING finger)
    0.00072   19.8   7.1    0.00072   19.8   7.1    2.2  1  zf-rbx1         RING-H2 zinc finger domain
     0.0011   18.6   5.7     0.0011   18.6   5.7    2.7  2  zf-RING_11      RING-like zinc finger
     0.0013   18.6   8.8     0.0013   18.6   8.8    2.0  1  zf-C3HC4        Zinc finger, C3HC4 type (RING finger)
     0.0017   18.3   6.0     0.0017   18.3   6.0    2.9  2  zf-RING_UBOX    RING-type zinc-finger
      0.002   17.9   3.9      0.039   13.8   1.2    2.5  2  GIT_CC          GIT coiled-coil Rho guanine nucleotide exchan
     0.0023   17.9   7.9     0.0023   17.9   7.9    2.4  1  zf-RING_5       zinc-RING finger domain
     0.0025   18.2  12.7      0.004   17.6   2.5    2.5  2  ZapB            Cell division protein ZapB
     0.0033   15.7   0.7     0.0066   14.7   0.7    1.5  1  COG6            Conserved oligomeric complex COG6
     0.0095   15.8   0.5      0.029   14.2   0.5    1.8  1  Spc29           Spindle Pole Component 29
  ------ inclusion threshold ------
      0.012   15.5   3.4      0.012   15.5   3.4    2.0  1  zf-RING_6       zf-RING of BARD1-type protein
      0.014   15.8   1.5        1.2    9.7   0.4    3.0  3  Cep57_MT_bd     Centrosome microtubule-binding domain of Cep5
      0.018   15.1   6.5      0.025   14.6   5.2    1.9  1  zf-ANAPC11      Anaphase-promoting complex subunit 11 RING-H2
      0.057   13.4   8.4       0.11   12.5   8.4    1.4  1  JAKMIP_CC3      JAKMIP CC3 domain
       0.19   11.2   6.9       0.32   10.4   6.9    1.3  1  MIF4G_like_2    MIF4G like
       0.31   10.6   5.0       0.57    9.7   5.0    1.4  1  Exonuc_VII_L    Exonuclease VII, large subunit
       0.36    9.9   3.8       0.15   11.2   0.7    1.6  1  ALS2CR11        Amyotrophic lateral sclerosis 2 candidate 11
       0.44   10.5  21.3      0.023   14.6   8.9    3.3  3  Prok-RING_4     Prokaryotic RING finger family 4
        3.2    7.8  19.8        6.8    6.8  19.8    1.6  1  TPR_MLP1_2      TPR/MLP1/MLP2-like protein
        5.3    7.6  16.9       0.39   11.3   9.4    2.4  2  Striatin        Striatin family


Domain annotation for each model (and alignments):
>> BRAP2  BRCA1-associated protein 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.8   0.0   2.5e-37   1.9e-34       4      92 ..     274     363 ..     271     369 .. 0.96

  Alignments for each domain:
  == domain 1  score: 117.8 bits;  conditional E-value: 2.5e-37
       BRAP2   4 vsrstllcilavPsylsladllkFvg.svlekvseiriirdgkenrymvLikfkdqesadeFykefngkkFssleeevChvvfvkevevt 92 
                 ++++++lcilavPsyls+ad+l Fvg ++ ++vs++r+i++++ nrymvL+kf++ ++a e+++e+ngk F+s+e+e+Chvvfvk+ve++
  EEA20172.1 274 DEDCSILCILAVPSYLSPADFLGFVGeETRDEVSHFRMIKTARANRYMVLMKFRNGKKAREWQREWNGKVFNSMEPETCHVVFVKSVEIE 363
                 68999********************989************************************************************97 PP

>> zf-UBP  Zn-finger in ubiquitin-hydrolases and other protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.4   4.5   1.8e-23   1.4e-20       1      61 [.     482     541 ..     482     544 .. 0.97

  Alignments for each domain:
  == domain 1  score: 73.4 bits;  conditional E-value: 1.8e-23
                 -TTTH--.SSEEEETTT--EEE-TTTT-HHHHHHHHH---EEEETTT--EEETTTTEEBE- CS
      zf-UBP   1 CseCnsenknlWlCLkCghvgCgrksnghalkHyeetrHplavdlstlsvycyscddeved 61 
                 Cs+C+se  nlW+CL Cg++gCgr+ + ha +H++et H++a+dlst++v++y  d +v++
  EEA20172.1 482 CSVCHSE-LNLWVCLICGSIGCGRYDEAHAFAHFKETSHAFAMDLSTQRVWDYVSDAYVHR 541
                 *****99.9**************************************************96 PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.2   9.5   6.6e-11   4.9e-08       2      44 .]     419     459 ..     418     459 .. 0.91
   2 ?   -2.6   5.3       9.6   7.2e+03       2      23 ..     481     499 ..     480     513 .. 0.73

  Alignments for each domain:
  == domain 1  score: 33.2 bits;  conditional E-value: 6.6e-11
   zf-RING_2   2 eCpICleelssadsvlllpCgHvfhreClerwlrssstCPlCr 44 
                 +Cp+Cle+++++  +l+  C+Hvfh++Cl++w  s   CP+Cr
  EEA20172.1 419 TCPVCLERMDETTGLLTIICQHVFHCTCLQKWKGSG--CPVCR 459
                 7********9999988666*************9777..****9 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 9.6
   zf-RING_2   2 eCpICleelssadsvlllpCgH 23 
                 eC++C +el+   +++   Cg 
  EEA20172.1 481 ECSVCHSELNLWVCLI---CGS 499
                 8****99997655544...554 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   9.7   2.1e-08   1.5e-05       2      40 .]     420     458 ..     419     458 .. 0.87

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 2.1e-08
  zf-C3HC4_2   2 CpiCldmlkdps..vvtpCgHvfCqkCilrsLeekneCPlC 40 
                 Cp+Cl+++ +++   ++ C+Hvf+  C++++  +++ CP+C
  EEA20172.1 420 CPVCLERMDETTglLTIICQHVFHCTCLQKW--KGSGCPVC 458
                 ********986522667*************9..899***** PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   5.1   5.9e-07   0.00044       4      47 ..     419     462 ..     416     465 .. 0.78
   2 ?    1.2   6.2      0.44   3.3e+02       3      26 ..     480     502 ..     478     504 .. 0.85

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 5.9e-07
                 B-TTTSSS.BS-EEETT..EEEEEE-HHHHHHHHHTT-B-TTT--B- CS
  zf-C3HC4_3   4 eCviCler.prnvvllp..CgHlvlCeeCaekllkrkkkCpiCrrpi 47 
                 +C++Cler ++++ ll   C+H++ C +C++k+  +   Cp+Cr   
  EEA20172.1 419 TCPVCLERmDETTGLLTiiCQHVFHC-TCLQKW--KGSGCPVCRYTL 462
                 7******954444444445****998.6*****..99*******766 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.44
                 SB-TTTSSSBS-EEETTEEEEEE- CS
  zf-C3HC4_3   3 eeCviClerprnvvllpCgHlvlC 26 
                  eC++C+++   +v+l Cg +  C
  EEA20172.1 480 CECSVCHSELNLWVCLICGSI-GC 502
                 68****************987.44 PP

>> zf-rbx1  RING-H2 zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   7.1   9.7e-07   0.00072      13      55 .]     419     459 ..     416     459 .. 0.87

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 9.7e-07
     zf-rbx1  13 acieckapgdeecpvvlGeCgHaFHlhCiskWlktrkvCPlcr 55 
                 +c+ c +  de++ + +  C+H+FH  C++kW    + CP+cr
  EEA20172.1 419 TCPVCLERMDETTGLLTIICQHVFHCTCLQKWKG--SGCPVCR 459
                 6999999999987777789*************65..58****8 PP

>> zf-RING_11  RING-like zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   5.7   1.5e-06    0.0011       2      29 .]     420     447 ..     419     447 .. 0.97
   2 ?    1.4   2.1      0.35   2.6e+02       1      16 [.     481     496 ..     481     514 .. 0.78

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 1.5e-06
  zf-RING_11   2 CsICLeefkpgqalfilpCsHtFHfkCI 29 
                 C +CLe + +   l +  C H+FH+ C+
  EEA20172.1 420 CPVCLERMDETTGLLTIICQHVFHCTCL 447
                 ***************************5 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.35
  zf-RING_11   1 eCsICLeefkpgqalf 16 
                 eCs+C +e+    +l+
  EEA20172.1 481 ECSVCHSELNLWVCLI 496
                 9****99988776666 PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   8.8   1.7e-06    0.0013       1      41 []     420     458 ..     420     458 .. 0.96

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 1.7e-06
                 -TTT-S--SS-E...E-TTS--B-CHHHHHHHHCTSSB--TTT CS
    zf-C3HC4   1 CpiCleeakepn..elleCkHsfCskCirkilksrkkvkCPlC 41 
                 Cp+Cle + e++   ++ C+H f+++C++k+        CP+C
  EEA20172.1 420 CPVCLERMDETTglLTIICQHVFHCTCLQKWKG----SGCPVC 458
                 ************999999*************99....77***9 PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   6.0   2.3e-06    0.0017       1      31 [.     420     450 ..     420     458 .. 0.76
   2 ?   -0.0   0.1       1.3   9.4e+02       1       9 [.     455     463 ..     455     468 .. 0.84

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 2.3e-06
  zf-RING_UBOX   1 CpIClelftdP..lvl.pCGHtFCreClwelsks 31 
                   Cp+Cle +++   l++  C+H+F+  Cl+   k+
    EEA20172.1 420 CPVCLERMDETtgLLTiICQHVFHCTCLQ---KW 450
                   *********776855446**********2...22 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 1.3
  zf-RING_UBOX   1 CpIClelft 9  
                   Cp+C+ +++
    EEA20172.1 455 CPVCRYTLD 463
                   ****98775 PP

>> GIT_CC  GIT coiled-coil Rho guanine nucleotide exchange factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.1     0.063        47      37      60 ..     621     644 ..     607     646 .. 0.82
   2 !   13.8   1.2   5.2e-05     0.039      29      66 .]     670     707 ..     666     707 .. 0.89

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.063
      GIT_CC  37 kvNtslsdelrlLQskvqkLqaeN 60 
                 ++ ++ +++l++LQ+  + L+++N
  EEA20172.1 621 EAAEKATQQLNELQQRYDALAKDN 644
                 55567789**************99 PP

  == domain 2  score: 13.8 bits;  conditional E-value: 5.2e-05
      GIT_CC  29 eakiqqLlkvNtslsdelrlLQskvqkLqaeNaqlrdq 66 
                 e  + + +++N++l + ++lL ++v+kL+aeNa+l +q
  EEA20172.1 670 EKEWREEKAMNENLVKRVELLSEEVTKLKAENADLSEQ 707
                 666777789*************************9876 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   7.9   3.1e-06    0.0023       2      43 ..     420     459 ..     419     460 .. 0.96

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 3.1e-06
   zf-RING_5   2 CnkCfeklskeekfyltsCgHifCekClkkllekeavCpiCr 43 
                 C++C e++ ++ +  +  C+H+f+ +Cl+k +     Cp+Cr
  EEA20172.1 420 CPVCLERMDETTGLLTIICQHVFHCTCLQKWK--GSGCPVCR 459
                 ********99999*******************..*******8 PP

>> ZapB  Cell division protein ZapB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   5.3      0.12        87       3      53 ..     627     678 ..     624     683 .. 0.76
   2 !   17.6   2.5   5.3e-06     0.004      15      53 ..     682     723 ..     675     745 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.12
        ZapB   3 lelLeqLEskiqkai.dtitlLqmeieeLkeeneelkeenreleeeneqlke 53 
                  ++L++L+++++++  d++  L +e ++ +++ e+ +  +r+le+e  ++k+
  EEA20172.1 627 TQQLNELQQRYDALAkDNVPGLEKEKDRAERRAEKFEIMARKLEKEWREEKA 678
                 5889999999998765888899999999999998888888888866655554 PP

  == domain 2  score: 17.6 bits;  conditional E-value: 5.3e-06
        ZapB  15 kaidtitlLqmeieeLkeeneelkeenrele...eeneqlke 53 
                 +++ +++lL++e+ +Lk+en+ l+e+nr l+   +  e+lke
  EEA20172.1 682 NLVKRVELLSEEVTKLKAENADLSEQNRDLTffiSGSEKLKE 723
                 7999**************************988844444443 PP

>> COG6  Conserved oligomeric complex COG6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.7   8.8e-06    0.0066     382     480 ..     540     642 ..     531     707 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 8.8e-06
        COG6 382 fsllkdklakllpelppsd...LspPewlsealskllell.etyesslaseaserekdfeevlsalldpllqacersakklekkdkaifliNcldliqs 476
                  +++++k++  l+elp++d   L pP+w   + ++ le +  +y+  l+s+ +++ + fee+++ ++d+  +a+  ++++le+ +ka+ ++N l++ + 
  EEA20172.1 540 HRIIQSKTDGKLVELPAADnsaLDPPDWTDAVPREKLENMsVEYTHLLTSQLESQRAYFEEIVERAVDKASKASAGASAALEAAEKATQQLNELQQRYD 638
                 5678888888888888655566********99876665550556665555444449************************************9998777 PP

        COG6 477 tLsp 480
                 +L++
  EEA20172.1 639 ALAK 642
                 7765 PP

>> Spc29  Spindle Pole Component 29
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.5   3.8e-05     0.029     117     166 ..     650     699 ..     615     745 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 3.8e-05
       Spc29 117 kkivelekklddqkleIkeLkreleqqrtvnseLqekvaeleeevkrlaa 166
                 k+ ++ e+  ++ +++ ++L++e  +++++n++L ++v+ l eev +l+a
  EEA20172.1 650 KEKDRAERRAEKFEIMARKLEKEWREEKAMNENLVKRVELLSEEVTKLKA 699
                 5668999999***********************************88865 PP

>> zf-RING_6  zf-RING of BARD1-type protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.5   3.4   1.6e-05     0.012       9      47 ..     419     460 ..     413     464 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1.6e-05
   zf-RING_6   9 rcsrctdilrepvclgg..cehifcsncisdcfgsgcpvc.y 47 
                  c  c + + e   l    c+h+f   c+    gsgcpvc y
  EEA20172.1 419 TCPVCLERMDETTGLLTiiCQHVFHCTCLQKWKGSGCPVCrY 460
                 5666777676666554333*********************44 PP

>> Cep57_MT_bd  Centrosome microtubule-binding domain of Cep57
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.0      0.12        93      16      58 ..     298     340 ..     286     348 .. 0.79
   2 ?   -2.5   0.1       9.9   7.4e+03      30      42 ..     629     641 ..     623     660 .. 0.72
   3 ?    9.7   0.4    0.0016       1.2       3      41 ..     673     711 ..     671     727 .. 0.89

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.12
  Cep57_MT_bd  16 vlkeLedEfehlklelqelaaqynaldpslgkrkRkdLaeele 58 
                  v +e  dE++h +++ +  a +y+ l +  + +k ++ ++e++
   EEA20172.1 298 VGEETRDEVSHFRMIKTARANRYMVLMKFRNGKKAREWQREWN 340
                  557899*****************99988777777777777776 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 9.9
  Cep57_MT_bd  30 elqelaaqynald 42 
                  +l el+++y al 
   EEA20172.1 629 QLNELQQRYDALA 641
                  5666777776664 PP

  == domain 3  score: 9.7 bits;  conditional E-value: 0.0016
  Cep57_MT_bd   3 lrpsqspkeaLaevlkeLedEfehlklelqelaaqynal 41 
                   r+ ++ +e+L + ++ L +E+++lk+e ++l++q ++l
   EEA20172.1 673 WREEKAMNENLVKRVELLSEEVTKLKAENADLSEQNRDL 711
                  6899999***************************97776 PP

>> zf-ANAPC11  Anaphase-promoting complex subunit 11 RING-H2 finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   5.2   3.4e-05     0.025      34      80 ..     419     461 ..     417     465 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 3.4e-05
                 --TTCSTTTTTS-.EEEBTTS-EEEHHHHHHHHHHHSTSSB-TTTSSB CS
  zf-ANAPC11  34 tcpsckfpGddcp.lvlGkckhnfhlhcilkwletetskglcpmcrqt 80 
                 tcp c    d+ + l+   c+h+fh  c++kw       + cp+cr t
  EEA20172.1 419 TCPVCLERMDETTgLLTIICQHVFHCTCLQKWKG-----SGCPVCRYT 461
                 8****99999876255556*************54.....469999976 PP

>> JAKMIP_CC3  JAKMIP CC3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   8.4   0.00014      0.11     104     191 ..     621     720 ..     560     728 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00014
  JAKMIP_CC3 104 erelkareqleselrktkskikdLeeaLaqk................GqdskwveekQalikrnqeLvekikkleeeeskLkqeiqdlrdqnelLEfri 186
                 e   ka +ql++  +++ +  kd    L+++                  ++ w eek      n++Lv +++ l ee +kLk+e  dl +qn+ L f i
  EEA20172.1 621 EAAEKATQQLNELQQRYDALAKDNVPGLEKEkdraerraekfeimarKLEKEWREEKA----MNENLVKRVELLSEEVTKLKAENADLSEQNRDLTFFI 715
                 4444555555555555555555555555544666677777777777789999****99....9999******************************999 PP

  JAKMIP_CC3 187 leleE 191
                 +  e 
  EEA20172.1 716 SGSEK 720
                 87765 PP

>> MIF4G_like_2  MIF4G like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   6.9   0.00043      0.32     140     240 ..     589     706 ..     579     729 .. 0.73

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00043
  MIF4G_like_2 140 knegltrayvwEllkrtlskvnkrvkkvrqeleelkkkeeee...kak.............eeed.....keeeeeleraeekleaaqkeqkelfli 215
                   ++ + +ray  E++ r+++k++k    ++  le+++k++++    + +             e  +     + + e+ e +  kle++ +e+k++ + 
    EEA20172.1 589 SQLESQRAYFEEIVERAVDKASKASAGASAALEAAEKATQQLnelQ-QrydalakdnvpglE--KekdraERRAEKFEIMARKLEKEWREEKAMNEN 682
                   56778999****************8888888877777766655541.124444333455541..0556778888********************999 PP

  MIF4G_like_2 216 vferlveilsesleeletsgseent 240
                   +++r ve+lse + +l++++ + ++
    EEA20172.1 683 LVKR-VELLSEEVTKLKAENADLSE 706
                   9998.56666665666666555443 PP

>> Exonuc_VII_L  Exonuclease VII, large subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   5.0   0.00077      0.57     145     257 ..     587     705 ..     545     726 .. 0.48

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00077
  Exonuc_VII_L 145 leeqleelerrlekaikrlleekkqrleklasrlkspeellerkrqrldeleerleralkkq...lkkkrerleelkerlk.......ekleekker 231
                   l++qle++++ +e+ ++r+++++++    ++ +     e  e+++q+l+el++r ++  k +   l+k++ r e+ +e+++       ++ +e+k+ 
    EEA20172.1 587 LTSQLESQRAYFEEIVERAVDKASKASAGASAA----LEAAEKATQQLNELQQRYDALAKDNvpgLEKEKDRAERRAEKFEimarkleKEWREEKAM 679
                   234444444444444444443333333333222....333344444444444444443223344455555555555444433332222333333333 PP

  Exonuc_VII_L 232 lkklkerlelleekkerleeleekle 257
                    ++l +r+ell+e+ ++l++  + l+
    EEA20172.1 680 NENLVKRVELLSEEVTKLKAENADLS 705
                   33333333344444444333333333 PP

>> ALS2CR11  Amyotrophic lateral sclerosis 2 candidate 11
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.7    0.0002      0.15     240     313 ..     571     651 ..     568     660 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.0002
    ALS2CR11 240 kPrerlekmkkeyrnlntWi..ekanylegilnPklekkdskesnvdealesek...edlse..ekeeevkaldvplinee 313
                  Pre+le+m  ey +l t     + +y+e+i++ +++k  + ++  + ale  +   ++l+e  ++ +     +vp +++e
  EEA20172.1 571 VPREKLENMSVEYTHLLTSQleSQRAYFEEIVERAVDKASKASAGASAALEAAEkatQQLNElqQRYDALAKDNVPGLEKE 651
                 5**************98864225678*******999887776554444444333100333221023333444455555555 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.1     0.058        43      30      43 ..     417     430 ..     413     437 .. 0.83
   2 ?   14.6   8.9   3.1e-05     0.023       1      41 [.     420     463 ..     420     466 .. 0.75
   3 ?   -3.1   4.6        10   7.5e+03      21      37 ..     482     498 ..     474     504 .. 0.73

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.058
  Prok-RING_4  30 lssCPlCqrrisks 43 
                  l +CP+C +r++++
   EEA20172.1 417 LPTCPVCLERMDET 430
                  559*****999876 PP

  == domain 2  score: 14.6 bits;  conditional E-value: 3.1e-05
  Prok-RING_4   1 CvlCgeq...ekkailepCgHlvCkeCfdskdlssCPlCqrris 41 
                  C +C e+    +    + C+H++  +C+++++ s+CP+C+  ++
   EEA20172.1 420 CPVCLERmdeTTGLLTIICQHVFHCTCLQKWKGSGCPVCRYTLD 463
                  556665544344445567****9999*************98876 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 10
  Prok-RING_4  21 CkeCfdskdlssCPlCq 37 
                  C  C ++ +l  C +C 
   EEA20172.1 482 CSVCHSELNLWVCLICG 498
                  77777777777777775 PP

>> TPR_MLP1_2  TPR/MLP1/MLP2-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8  19.8    0.0091       6.8       6     122 ..     598     711 ..     586     712 .. 0.91

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0091
  TPR_MLP1_2   6 leeeikslkeekeeaeaklqklqedlekqaeiakeaqqkYerelvkhaedvkelqalreelnelkaeiaelkaeaesakaeleeseesweeqkeeleke 104
                 +ee ++++ +++++a a ++++ e  ek +++++e qq+Y     + +++v  l++ ++++++  ++ + +  ++e+   e ++  e++ ++ e l +e
  EEA20172.1 598 FEEIVERAVDKASKASAGASAALEAAEKATQQLNELQQRYDA---LAKDNVPGLEKEKDRAERRAEKFEIMARKLEKEWREEKAMNENLVKRVELLSEE 693
                 66778899999***************************9985...778999999999999999999999999999999999999999999********* PP

  TPR_MLP1_2 105 lselekriedlneqNklL 122
                 +++l++   dl+eqN+ L
  EEA20172.1 694 VTKLKAENADLSEQNRDL 711
                 ***************855 PP

>> Striatin  Striatin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.8       1.4   1.1e+03      45     102 ..     574     632 ..     571     646 .. 0.54
   2 ?   11.3   9.4   0.00053      0.39      17      77 ..     651     719 ..     648     754 .. 0.64

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 1.4
    Striatin  45 enlkkdlvrrikmLEyalkqerakylkl.kegtsaakenkkkekeeeeaeeeekseees 102
                 e+l++  v +  +L  +l+ +ra + +  ++++++a++ +  ++   ea+e+++++ ++
  EEA20172.1 574 EKLENMSVEYTHLLTSQLESQRAYFEEIvERAVDKASKASAGASAALEAAEKATQQLNE 632
                 56677777788888889999998877764333333333333333333333333333333 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00053
    Striatin  17 erdRneweiEraEmkarIakLegerrgaenlkkdlvrrikmLEya...lkqerakylkl.......kegts 77 
                 e dR+e   E+ E+ ar  kLe e r++++++++lv+r+++L  +   lk e a   ++       ++g++
  EEA20172.1 651 EKDRAERRAEKFEIMAR--KLEKEWREEKAMNENLVKRVELLSEEvtkLKAENADLSEQnrdltffISGSE 719
                 89**************9..9**********************98833355555543333554444412222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (755 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1558  (0.0868983); expected 358.6 (0.02)
Passed bias filter:                      687  (0.0383178); expected 358.6 (0.02)
Passed Vit filter:                       117  (0.00652574); expected 17.9 (0.001)
Passed Fwd filter:                        31  (0.00172904); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              24  [number of targets reported over threshold]
# CPU time: 0.85u 0.30s 00:00:01.14 Elapsed: 00:00:00.48
# Mc/sec: 4712.14
//
Query:       EEA20173.1  [L=305]
Description: polyubiquitin UbiD/Ubi4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   4.4e-135  439.7  20.4    3.3e-33  113.3   0.6    4.0  4  ubiquitin        Ubiquitin family
    6.6e-64  211.7  21.0      2e-15   56.4   0.7    4.0  4  Rad60-SLD        Ubiquitin-2 like Rad60 SUMO-like
    8.1e-23   80.7  10.7    0.00043   20.7   0.1    5.8  4  Ubiquitin_2      Ubiquitin-like domain
    1.7e-16   59.9   3.0      0.027   14.4   0.0    4.2  4  TBK1_ULD         TANK binding kinase 1 ubiquitin-like domain
      3e-15   56.3   7.7      0.029   14.7   0.1    4.1  4  Ubiquitin_5      Ubiquitin-like domain
    2.1e-14   53.6   2.6       0.12   12.4   0.0    5.0  4  Rad60-SLD_2      Ubiquitin-2 like Rad60 SUMO-like
    5.6e-13   49.3   1.4       0.37   11.4   0.0    4.2  4  DUF2407          DUF2407 ubiquitin-like domain
    5.9e-11   42.5   0.8        0.6    9.9   0.0    4.1  4  Sde2_N_Ubi       Silencing defective 2 N-terminal ubiquitin d
    3.7e-07   30.1  24.0         16    5.6   0.2    8.0  8  Ubiquitin_4      Ubiquitin-like domain
    3.1e-06   26.7   0.5        1.8    7.8   0.0    3.3  3  Methyltrans_RNA  RNA methyltransferase
    3.8e-06   27.0   2.5         13    6.1   0.0    4.2  4  DUF3861          Domain of Unknown Function with PDB structur
    7.1e-06   26.3   0.0         30    5.1   0.0    4.6  4  DUF2870          Protein of unknown function (DUF2870)
    1.2e-05   25.0   4.7         10    6.1   0.0    4.3  4  ACT_5            ACT domain
      4e-05   24.3   0.1         52    4.7   0.0    4.1  4  Big_7            Bacterial Ig domain
    0.00014   21.9   4.3        7.1    6.8   0.0    4.0  4  UDP-g_GGTase     UDP-glucose:Glycoprotein Glucosyltransferase
    0.00043   19.8   0.0         23    4.3   0.0    3.9  4  DUF969           Protein of unknown function (DUF969)
    0.00091   19.3   6.2         29    4.9   0.1    4.3  4  YcgR_2           Flagellar protein YcgR
      0.003   18.1   0.1    1.4e+02    3.1   0.0    4.0  4  DUF493           Protein of unknown function (DUF493)
     0.0037   16.9   0.0      1e+02    2.7   0.0    4.1  4  Raf1_HTH         Rubisco accumulation factor 1 helix turn hel
     0.0052   17.4   1.0    1.4e+02    3.1   0.0    4.2  4  ACT_4            ACT domain
     0.0068   16.5   0.0         91    3.3   0.0    4.3  4  ORF11CD3         ORF11CD3 domain
  ------ inclusion threshold ------
       0.11   12.7   5.8    1.1e+02    3.1   0.1    4.1  4  ProRS-C_2        Prolyl-tRNA synthetase, C-terminal
       0.12   11.2   0.0         61    2.4   0.0    3.0  3  Baculo_p48       Baculovirus P48 protein
       0.14   12.4  27.2        6.2    7.1   1.4    4.3  4  Tash_PEST        Tash protein PEST motif
       0.23   11.3   6.3    1.1e+02    2.8   0.0    5.2  4  Myosin_N         Myosin N-terminal SH3-like domain
       0.23   11.0   1.5      2e+02    1.6   0.0    3.9  4  HAMP_N3          HAMP N-terminal domain 3
       0.29   10.8   4.0      1e+02    2.6   0.0    4.1  4  DMA              DMRTA motif
        1.9    8.3   9.3         96    2.8   0.1    4.2  4  PI3K_p85B        PI3-kinase family, p85-binding domain


Domain annotation for each model (and alignments):
>> ubiquitin  Ubiquitin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.3   0.6   5.1e-36   3.3e-33       1      72 []       3      74 ..       3      74 .. 0.99
   2 !  113.3   0.6   5.1e-36   3.3e-33       1      72 []      79     150 ..      79     150 .. 0.99
   3 !  113.3   0.6   5.1e-36   3.3e-33       1      72 []     155     226 ..     155     226 .. 0.99
   4 !  113.3   0.6   5.1e-36   3.3e-33       1      72 []     231     302 ..     231     302 .. 0.99

  Alignments for each domain:
  == domain 1  score: 113.3 bits;  conditional E-value: 5.1e-36
                EEEEETTSEEEEEEEETTSBHHHHHHHHHHHHTSSGGGEEEEETTEEE-TTSBHGGHTTSTTEEEEEEESSC CS
   ubiquitin  1 itvktldgkkitleveesdtveelKekiaekegipaeqqrLiysGkvLedertleeygiqdgstlhlvlrlr 72
                i+vktl+gk+itleve+sdt++++K ki++kegip++qqrLi++Gk+Led rtl++y+iq++stlhlvlrlr
  EEA20173.1  3 IFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLR 74
                9********************************************************************986 PP

  == domain 2  score: 113.3 bits;  conditional E-value: 5.1e-36
                 EEEEETTSEEEEEEEETTSBHHHHHHHHHHHHTSSGGGEEEEETTEEE-TTSBHGGHTTSTTEEEEEEESSC CS
   ubiquitin   1 itvktldgkkitleveesdtveelKekiaekegipaeqqrLiysGkvLedertleeygiqdgstlhlvlrlr 72 
                 i+vktl+gk+itleve+sdt++++K ki++kegip++qqrLi++Gk+Led rtl++y+iq++stlhlvlrlr
  EEA20173.1  79 IFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLR 150
                 9********************************************************************986 PP

  == domain 3  score: 113.3 bits;  conditional E-value: 5.1e-36
                 EEEEETTSEEEEEEEETTSBHHHHHHHHHHHHTSSGGGEEEEETTEEE-TTSBHGGHTTSTTEEEEEEESSC CS
   ubiquitin   1 itvktldgkkitleveesdtveelKekiaekegipaeqqrLiysGkvLedertleeygiqdgstlhlvlrlr 72 
                 i+vktl+gk+itleve+sdt++++K ki++kegip++qqrLi++Gk+Led rtl++y+iq++stlhlvlrlr
  EEA20173.1 155 IFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLR 226
                 9********************************************************************986 PP

  == domain 4  score: 113.3 bits;  conditional E-value: 5.1e-36
                 EEEEETTSEEEEEEEETTSBHHHHHHHHHHHHTSSGGGEEEEETTEEE-TTSBHGGHTTSTTEEEEEEESSC CS
   ubiquitin   1 itvktldgkkitleveesdtveelKekiaekegipaeqqrLiysGkvLedertleeygiqdgstlhlvlrlr 72 
                 i+vktl+gk+itleve+sdt++++K ki++kegip++qqrLi++Gk+Led rtl++y+iq++stlhlvlrlr
  EEA20173.1 231 IFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLR 302
                 9********************************************************************986 PP

>> Rad60-SLD  Ubiquitin-2 like Rad60 SUMO-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.4   0.7   3.1e-18     2e-15       1      72 []       1      71 [.       1      71 [. 0.98
   2 !   56.4   0.7   3.1e-18     2e-15       1      72 []      77     147 ..      77     147 .. 0.98
   3 !   56.4   0.7   3.1e-18     2e-15       1      72 []     153     223 ..     153     223 .. 0.98
   4 !   56.4   0.7   3.1e-18     2e-15       1      72 []     229     299 ..     229     299 .. 0.98

  Alignments for each domain:
  == domain 1  score: 56.4 bits;  conditional E-value: 3.1e-18
                EEEEEEESSS--EEEEEETTSBHHHHHHHHHHHHT----TT-EEEETTEE--TTSBGGGSS--TTEEEEEEX CS
   Rad60-SLD  1 ikiilkgkdgkevkikVkptttvskLieayrkkkgipeeqkvrLiFDGeeLdpnstvedldiedgdtidvvi 72
                ++i++k+ +gk+++++V+++ t+ +++++ ++k+gip+ +++rLiF G++L++  t+ d+ i++++t+++v+
  EEA20173.1  1 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPP-DQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVL 71
                89************************************.******************************986 PP

  == domain 2  score: 56.4 bits;  conditional E-value: 3.1e-18
                 EEEEEEESSS--EEEEEETTSBHHHHHHHHHHHHT----TT-EEEETTEE--TTSBGGGSS--TTEEEEEEX CS
   Rad60-SLD   1 ikiilkgkdgkevkikVkptttvskLieayrkkkgipeeqkvrLiFDGeeLdpnstvedldiedgdtidvvi 72 
                 ++i++k+ +gk+++++V+++ t+ +++++ ++k+gip+ +++rLiF G++L++  t+ d+ i++++t+++v+
  EEA20173.1  77 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPP-DQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVL 147
                 89************************************.******************************986 PP

  == domain 3  score: 56.4 bits;  conditional E-value: 3.1e-18
                 EEEEEEESSS--EEEEEETTSBHHHHHHHHHHHHT----TT-EEEETTEE--TTSBGGGSS--TTEEEEEEX CS
   Rad60-SLD   1 ikiilkgkdgkevkikVkptttvskLieayrkkkgipeeqkvrLiFDGeeLdpnstvedldiedgdtidvvi 72 
                 ++i++k+ +gk+++++V+++ t+ +++++ ++k+gip+ +++rLiF G++L++  t+ d+ i++++t+++v+
  EEA20173.1 153 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPP-DQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVL 223
                 89************************************.******************************986 PP

  == domain 4  score: 56.4 bits;  conditional E-value: 3.1e-18
                 EEEEEEESSS--EEEEEETTSBHHHHHHHHHHHHT----TT-EEEETTEE--TTSBGGGSS--TTEEEEEEX CS
   Rad60-SLD   1 ikiilkgkdgkevkikVkptttvskLieayrkkkgipeeqkvrLiFDGeeLdpnstvedldiedgdtidvvi 72 
                 ++i++k+ +gk+++++V+++ t+ +++++ ++k+gip+ +++rLiF G++L++  t+ d+ i++++t+++v+
  EEA20173.1 229 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPP-DQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVL 299
                 89************************************.******************************986 PP

>> Ubiquitin_2  Ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5   0.1   7.4e-07   0.00047      17      80 ..      14      69 ..       2      70 .. 0.86
   2 !   20.7   0.1   6.7e-07   0.00043      15      80 ..      88     145 ..      77     146 .. 0.85
   3 !   20.7   0.1   6.7e-07   0.00043      15      80 ..     164     221 ..     153     222 .. 0.85
   4 !   20.7   0.1   6.7e-07   0.00043      15      80 ..     240     297 ..     229     298 .. 0.85

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 7.4e-07
                 EEEEETTSBHHHHHHHHHHHH---TTCEEEEEE.-SSSSEEECSSGCCSBCCCCT--TTEEEEE CS
  Ubiquitin_2 17 errfsksltieelKekLelitGtspasmrLqlyddkkdnevsklddddalLgsYgvkdgmrihV 80
                 +  +++s+ti+++K+k++   G++p+++rL +          k  +d ++L++Y+++  +++h 
   EEA20173.1 14 TLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFA--------GKQLEDGRTLSDYNIQKESTLHL 69
                 5667899************************99........56678999********9999995 PP

  == domain 2  score: 20.7 bits;  conditional E-value: 6.7e-07
                  EEEEEEETTSBHHHHHHHHHHHH---TTCEEEEEE.-SSSSEEECSSGCCSBCCCCT--TTEEEEE CS
  Ubiquitin_2  15 sserrfsksltieelKekLelitGtspasmrLqlyddkkdnevsklddddalLgsYgvkdgmrihV 80 
                    +  +++s+ti+++K+k++   G++p+++rL +          k  +d ++L++Y+++  +++h 
   EEA20173.1  88 TITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFA--------GKQLEDGRTLSDYNIQKESTLHL 145
                  556678899************************99........56678999********9999995 PP

  == domain 3  score: 20.7 bits;  conditional E-value: 6.7e-07
                  EEEEEEETTSBHHHHHHHHHHHH---TTCEEEEEE.-SSSSEEECSSGCCSBCCCCT--TTEEEEE CS
  Ubiquitin_2  15 sserrfsksltieelKekLelitGtspasmrLqlyddkkdnevsklddddalLgsYgvkdgmrihV 80 
                    +  +++s+ti+++K+k++   G++p+++rL +          k  +d ++L++Y+++  +++h 
   EEA20173.1 164 TITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFA--------GKQLEDGRTLSDYNIQKESTLHL 221
                  556678899************************99........56678999********9999995 PP

  == domain 4  score: 20.7 bits;  conditional E-value: 6.7e-07
                  EEEEEEETTSBHHHHHHHHHHHH---TTCEEEEEE.-SSSSEEECSSGCCSBCCCCT--TTEEEEE CS
  Ubiquitin_2  15 sserrfsksltieelKekLelitGtspasmrLqlyddkkdnevsklddddalLgsYgvkdgmrihV 80 
                    +  +++s+ti+++K+k++   G++p+++rL +          k  +d ++L++Y+++  +++h 
   EEA20173.1 240 TITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFA--------GKQLEDGRTLSDYNIQKESTLHL 297
                  556678899************************99........56678999********9999995 PP

>> TBK1_ULD  TANK binding kinase 1 ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   4.4e-05     0.028      19      53 ..      17      51 ..       5      70 .. 0.86
   2 !   14.4   0.0   4.2e-05     0.027      19      53 ..      93     127 ..      79     146 .. 0.86
   3 !   14.4   0.0   4.2e-05     0.027      19      53 ..     169     203 ..     155     222 .. 0.86
   4 !   14.4   0.0   4.3e-05     0.028      19      53 ..     245     279 ..     231     297 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 4.4e-05
    TBK1_ULD 19 ihpyntvaifqeevakqTkiaaekQellfeghrll 53
                +++ +t++++  +++++  i++++Q l+f g++l 
  EEA20173.1 17 VESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLE 51
                67899***************************973 PP

  == domain 2  score: 14.4 bits;  conditional E-value: 4.2e-05
    TBK1_ULD  19 ihpyntvaifqeevakqTkiaaekQellfeghrll 53 
                 +++ +t++++  +++++  i++++Q l+f g++l 
  EEA20173.1  93 VESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLE 127
                 67899***************************973 PP

  == domain 3  score: 14.4 bits;  conditional E-value: 4.2e-05
    TBK1_ULD  19 ihpyntvaifqeevakqTkiaaekQellfeghrll 53 
                 +++ +t++++  +++++  i++++Q l+f g++l 
  EEA20173.1 169 VESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLE 203
                 67899***************************973 PP

  == domain 4  score: 14.4 bits;  conditional E-value: 4.3e-05
    TBK1_ULD  19 ihpyntvaifqeevakqTkiaaekQellfeghrll 53 
                 +++ +t++++  +++++  i++++Q l+f g++l 
  EEA20173.1 245 VESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLE 279
                 67899***************************974 PP

>> Ubiquitin_5  Ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.1   4.8e-05     0.031      34      93 ..      13      73 ..       5      78 .. 0.83
   2 !   14.7   0.1   4.5e-05     0.029      34      93 ..      89     149 ..      79     154 .. 0.83
   3 !   14.7   0.1   4.5e-05     0.029      34      93 ..     165     225 ..     155     230 .. 0.83
   4 !   14.6   0.1   5.1e-05     0.032      34      92 ..     241     300 ..     231     304 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 4.8e-05
  Ubiquitin_5 34 klletkLdvtgkelvskiaeefglkensiKlilngklleldktLeeQgvknnskv.mvLkl 93
                  +le++ + t +++ ski ++ g+  ++ +li  gk+le ++tL + +++++s + +vL+l
   EEA20173.1 13 ITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLhLVLRL 73
                 55666666678899999999****99***********************999875467765 PP

  == domain 2  score: 14.7 bits;  conditional E-value: 4.5e-05
  Ubiquitin_5  34 klletkLdvtgkelvskiaeefglkensiKlilngklleldktLeeQgvknnskv.mvLkl 93 
                   +le++ + t +++ ski ++ g+  ++ +li  gk+le ++tL + +++++s + +vL+l
   EEA20173.1  89 ITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLhLVLRL 149
                  5566666667889999999*****99***********************999875467765 PP

  == domain 3  score: 14.7 bits;  conditional E-value: 4.5e-05
  Ubiquitin_5  34 klletkLdvtgkelvskiaeefglkensiKlilngklleldktLeeQgvknnskv.mvLkl 93 
                   +le++ + t +++ ski ++ g+  ++ +li  gk+le ++tL + +++++s + +vL+l
   EEA20173.1 165 ITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLhLVLRL 225
                  5566666667889999999*****99***********************999875467765 PP

  == domain 4  score: 14.6 bits;  conditional E-value: 5.1e-05
  Ubiquitin_5  34 klletkLdvtgkelvskiaeefglkensiKlilngklleldktLeeQgvknnskv.mvLk 92 
                   +le++ + t +++ ski ++ g+  ++ +li  gk+le ++tL + +++++s + +vL+
   EEA20173.1 241 ITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLhLVLR 300
                  5566666667889999999*****99***********************99987546666 PP

>> Rad60-SLD_2  Ubiquitin-2 like Rad60 SUMO-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.3   0.0   0.00021      0.13      18      87 ..      15      71 ..       2      75 .. 0.69
   2 !   12.4   0.0   0.00019      0.12      16      87 ..      89     147 ..      77     151 .. 0.69
   3 !   12.4   0.0   0.00019      0.12      16      87 ..     165     223 ..     153     227 .. 0.69
   4 !   12.4   0.0    0.0002      0.13      16      87 ..     241     299 ..     229     302 .. 0.68

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00021
                 EEEETT-BHHHHHHHHHHHS-TT-SSS--SCCCEEEEETTEEE-TTSBCCCCS-TTTTTTTS-EEEEEEE CS
  Rad60-SLD_2 18 vkfsdaatvaelkekviaqWPkdkeekpksvndlklilaGkiLennktlkelrlplgevkggvtvmHvvv 87
                 ++ ++++t++++k k+     +dke  p  +++ +li aGk Le+ +tl++++++        +++H+v+
   EEA20173.1 15 LEVESSDTIDNVKSKI-----QDKEGIP--PDQQRLIFAGKQLEDGRTLSDYNIQKE------STLHLVL 71
                 5666677777777777.....4555533..34559****************965433......3566665 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 0.00019
                  EEEEEETT-BHHHHHHHHHHHS-TT-SSS--SCCCEEEEETTEEE-TTSBCCCCS-TTTTTTTS-EEEEEEE CS
  Rad60-SLD_2  16 gpvkfsdaatvaelkekviaqWPkdkeekpksvndlklilaGkiLennktlkelrlplgevkggvtvmHvvv 87 
                    ++ ++++t++++k k+     +dke  p  +++ +li aGk Le+ +tl++++++        +++H+v+
   EEA20173.1  89 ITLEVESSDTIDNVKSKI-----QDKEGIP--PDQQRLIFAGKQLEDGRTLSDYNIQKE------STLHLVL 147
                  556667777777777777.....4555533..34559****************965433......3566665 PP

  == domain 3  score: 12.4 bits;  conditional E-value: 0.00019
                  EEEEEETT-BHHHHHHHHHHHS-TT-SSS--SCCCEEEEETTEEE-TTSBCCCCS-TTTTTTTS-EEEEEEE CS
  Rad60-SLD_2  16 gpvkfsdaatvaelkekviaqWPkdkeekpksvndlklilaGkiLennktlkelrlplgevkggvtvmHvvv 87 
                    ++ ++++t++++k k+     +dke  p  +++ +li aGk Le+ +tl++++++        +++H+v+
   EEA20173.1 165 ITLEVESSDTIDNVKSKI-----QDKEGIP--PDQQRLIFAGKQLEDGRTLSDYNIQKE------STLHLVL 223
                  556667777777777777.....4555533..34559****************965433......3566665 PP

  == domain 4  score: 12.4 bits;  conditional E-value: 0.0002
                  EEEEEETT-BHHHHHHHHHHHS-TT-SSS--SCCCEEEEETTEEE-TTSBCCCCS-TTTTTTTS-EEEEEEE CS
  Rad60-SLD_2  16 gpvkfsdaatvaelkekviaqWPkdkeekpksvndlklilaGkiLennktlkelrlplgevkggvtvmHvvv 87 
                    ++ ++++t++++k k+     +dke  p  +++ +li aGk Le+ +tl++++++        +++H+v+
   EEA20173.1 241 ITLEVESSDTIDNVKSKI-----QDKEGIP--PDQQRLIFAGKQLEDGRTLSDYNIQKE------STLHLVL 299
                  556667777777777777.....4555533..34559****************965433......3566665 PP

>> DUF2407  DUF2407 ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.0   0.00066      0.43      14      64 ..      13      59 ..       7      72 .. 0.80
   2 !   11.3   0.0   0.00062       0.4      14      63 ..      89     134 ..      77     146 .. 0.81
   3 !   11.3   0.0    0.0006      0.39      14      64 ..     165     211 ..     156     226 .. 0.81
   4 !   11.4   0.0   0.00058      0.37      14      63 ..     241     286 ..     220     298 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00066
     DUF2407 14 leLdipdpntttvagLkqliRerlpaelasrrLrLIyaGrlLedttslass 64
                ++L+++  ++ t+ ++k  i ++    +   + rLI+aG+ Led  +l++ 
  EEA20173.1 13 ITLEVE--SSDTIDNVKSKIQDKE--GIPPDQQRLIFAGKQLEDGRTLSDY 59
                566666..6789999999999987..67777789************99874 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00062
     DUF2407  14 leLdipdpntttvagLkqliRerlpaelasrrLrLIyaGrlLedttslas 63 
                 ++L+++  ++ t+ ++k  i ++    +   + rLI+aG+ Led  +l++
  EEA20173.1  89 ITLEVE--SSDTIDNVKSKIQDKE--GIPPDQQRLIFAGKQLEDGRTLSD 134
                 566666..6789999999999987..67777789************9986 PP

  == domain 3  score: 11.3 bits;  conditional E-value: 0.0006
     DUF2407  14 leLdipdpntttvagLkqliRerlpaelasrrLrLIyaGrlLedttslass 64 
                 ++L+++  ++ t+ ++k  i ++    +   + rLI+aG+ Led  +l++ 
  EEA20173.1 165 ITLEVE--SSDTIDNVKSKIQDKE--GIPPDQQRLIFAGKQLEDGRTLSDY 211
                 566666..6789999999999987..67777789************99874 PP

  == domain 4  score: 11.4 bits;  conditional E-value: 0.00058
     DUF2407  14 leLdipdpntttvagLkqliRerlpaelasrrLrLIyaGrlLedttslas 63 
                 ++L+++  ++ t+ ++k  i ++    +   + rLI+aG+ Led  +l++
  EEA20173.1 241 ITLEVE--SSDTIDNVKSKIQDKE--GIPPDQQRLIFAGKQLEDGRTLSD 286
                 566666..6789999999999987..67777789************9986 PP

>> Sde2_N_Ubi  Silencing defective 2 N-terminal ubiquitin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   0.0    0.0011      0.71       2      88 ..       2      76 ..       1      77 [. 0.84
   2 !    9.7   0.0    0.0011      0.71       2      88 ..      78     152 ..      77     153 .. 0.84
   3 !    9.8   0.0     0.001      0.67       2      88 ..     154     228 ..     153     230 .. 0.84
   4 !    9.9   0.0   0.00094       0.6       2      88 ..     230     304 ..     229     305 .] 0.84

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0011
  Sde2_N_Ubi  2 nvlvssfdgltlpstlsltlpstatvsdlvdklserlpeslkesliLttvsnkqlllssdvslssllassadsellslrllvrlrGG 88
                +++v+++ g+    t++l++ s+ t+ ++ +k++++      +   L  + + ql  ++  +ls++  ++++    +l+l++rlrGG
  EEA20173.1  2 QIFVKTLTGK----TITLEVESSDTIDNVKSKIQDKEGIPPDQ-QRLIFAGK-QL--EDGRTLSDYNIQKES----TLHLVLRLRGG 76
                8999999996....999*****************998877555.45555544.66..99999****999999....99********9 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.0011
  Sde2_N_Ubi   2 nvlvssfdgltlpstlsltlpstatvsdlvdklserlpeslkesliLttvsnkqlllssdvslssllassadsellslrllvrlrGG 88 
                 +++v+++ g+    t++l++ s+ t+ ++ +k++++      +   L  + + ql  ++  +ls++  ++++    +l+l++rlrGG
  EEA20173.1  78 QIFVKTLTGK----TITLEVESSDTIDNVKSKIQDKEGIPPDQ-QRLIFAGK-QL--EDGRTLSDYNIQKES----TLHLVLRLRGG 152
                 8999999996....999*****************998877555.45555544.66..99999****999999....99********9 PP

  == domain 3  score: 9.8 bits;  conditional E-value: 0.001
  Sde2_N_Ubi   2 nvlvssfdgltlpstlsltlpstatvsdlvdklserlpeslkesliLttvsnkqlllssdvslssllassadsellslrllvrlrGG 88 
                 +++v+++ g+    t++l++ s+ t+ ++ +k++++      +   L  + + ql  ++  +ls++  ++++    +l+l++rlrGG
  EEA20173.1 154 QIFVKTLTGK----TITLEVESSDTIDNVKSKIQDKEGIPPDQ-QRLIFAGK-QL--EDGRTLSDYNIQKES----TLHLVLRLRGG 228
                 8999999996....999*****************998877555.45555544.66..99999****999999....99********9 PP

  == domain 4  score: 9.9 bits;  conditional E-value: 0.00094
  Sde2_N_Ubi   2 nvlvssfdgltlpstlsltlpstatvsdlvdklserlpeslkesliLttvsnkqlllssdvslssllassadsellslrllvrlrGG 88 
                 +++v+++ g+    t++l++ s+ t+ ++ +k++++      +   L  + + ql  ++  +ls++  ++++    +l+l++rlrGG
  EEA20173.1 230 QIFVKTLTGK----TITLEVESSDTIDNVKSKIQDKEGIPPDQ-QRLIFAGK-QL--EDGRTLSDYNIQKES----TLHLVLRLRGG 304
                 8999999996....999*****************998877555.45555554.66..99999****999999....9*********9 PP

>> Ubiquitin_4  Ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.2     0.026        16       1      32 [.       1      32 [.       1      36 [. 0.94
   2 ?    5.0   0.0     0.039        25      58      86 ..      43      70 ..      39      73 .. 0.83
   3 ?    5.6   0.2     0.026        16       1      32 [.      77     108 ..      77     112 .. 0.94
   4 ?    5.0   0.0     0.039        25      58      86 ..     119     146 ..     115     149 .. 0.83
   5 ?    5.6   0.2     0.026        16       1      32 [.     153     184 ..     153     188 .. 0.94
   6 ?    5.0   0.0     0.039        25      58      86 ..     195     222 ..     191     225 .. 0.83
   7 ?    5.6   0.2     0.026        16       1      32 [.     229     260 ..     229     264 .. 0.94
   8 ?    5.0   0.0     0.039        25      58      86 ..     271     298 ..     267     301 .. 0.83

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.026
  Ubiquitin_4  1 lkvtvkkldgeslevvvkqnatvkdLkkaier 32
                 +++ vk l g+++ ++v+++ t+ ++k  i+ 
   EEA20173.1  1 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQD 32
                 7899*************************997 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.039
  Ubiquitin_4 58 LsfegekLkddkaklkeygirnkselsFv 86
                 L+f g++L+ d  +l++y i+++s+l+ v
   EEA20173.1 43 LIFAGKQLE-DGRTLSDYNIQKESTLHLV 70
                 889999986.6789***********9976 PP

  == domain 3  score: 5.6 bits;  conditional E-value: 0.026
  Ubiquitin_4   1 lkvtvkkldgeslevvvkqnatvkdLkkaier 32 
                  +++ vk l g+++ ++v+++ t+ ++k  i+ 
   EEA20173.1  77 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQD 108
                  7899*************************997 PP

  == domain 4  score: 5.0 bits;  conditional E-value: 0.039
  Ubiquitin_4  58 LsfegekLkddkaklkeygirnkselsFv 86 
                  L+f g++L+ d  +l++y i+++s+l+ v
   EEA20173.1 119 LIFAGKQLE-DGRTLSDYNIQKESTLHLV 146
                  889999986.6789***********9976 PP

  == domain 5  score: 5.6 bits;  conditional E-value: 0.026
  Ubiquitin_4   1 lkvtvkkldgeslevvvkqnatvkdLkkaier 32 
                  +++ vk l g+++ ++v+++ t+ ++k  i+ 
   EEA20173.1 153 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQD 184
                  7899*************************997 PP

  == domain 6  score: 5.0 bits;  conditional E-value: 0.039
  Ubiquitin_4  58 LsfegekLkddkaklkeygirnkselsFv 86 
                  L+f g++L+ d  +l++y i+++s+l+ v
   EEA20173.1 195 LIFAGKQLE-DGRTLSDYNIQKESTLHLV 222
                  889999986.6789***********9976 PP

  == domain 7  score: 5.6 bits;  conditional E-value: 0.026
  Ubiquitin_4   1 lkvtvkkldgeslevvvkqnatvkdLkkaier 32 
                  +++ vk l g+++ ++v+++ t+ ++k  i+ 
   EEA20173.1 229 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQD 260
                  7899*************************997 PP

  == domain 8  score: 5.0 bits;  conditional E-value: 0.039
  Ubiquitin_4  58 LsfegekLkddkaklkeygirnkselsFv 86 
                  L+f g++L+ d  +l++y i+++s+l+ v
   EEA20173.1 271 LIFAGKQLE-DGRTLSDYNIQKESTLHLV 298
                  889999986.6789***********9976 PP

>> Methyltrans_RNA  RNA methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.8   0.0     0.003       1.9       2      61 ..      60     118 ..      59     124 .. 0.82
   2 !    7.8   0.0     0.003       1.9       2      61 ..     136     194 ..     135     200 .. 0.82
   3 !    7.8   0.0    0.0028       1.8       2      61 ..     212     270 ..     211     279 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.003
                      EEEHHHHHHHHTTTT--TT-EEEEEESSSEEEEEEEEEEESS.EEEEEEEEEEE---SSSS CS
  Methyltrans_RNA   2 sltdeeahHlvkVlRlkegdeiklfdgdgkeyeaeieeiskk.kvtvkilekeeenkespe 61 
                      ++++e + Hl  VlRl+ g +i +    gk ++ e+e+ +   +v+ ki++ke +++++++
       EEA20173.1  60 NIQKESTLHL--VLRLRGGMQIFVKTLTGKTITLEVESSDTIdNVKSKIQDKEGIPPDQQR 118
                      5788999999..*************************998751557778777777766655 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.003
                      EEEHHHHHHHHTTTT--TT-EEEEEESSSEEEEEEEEEEESS.EEEEEEEEEEE---SSSS CS
  Methyltrans_RNA   2 sltdeeahHlvkVlRlkegdeiklfdgdgkeyeaeieeiskk.kvtvkilekeeenkespe 61 
                      ++++e + Hl  VlRl+ g +i +    gk ++ e+e+ +   +v+ ki++ke +++++++
       EEA20173.1 136 NIQKESTLHL--VLRLRGGMQIFVKTLTGKTITLEVESSDTIdNVKSKIQDKEGIPPDQQR 194
                      5788999999..*************************998751557778777777766655 PP

  == domain 3  score: 7.8 bits;  conditional E-value: 0.0028
                      EEEHHHHHHHHTTTT--TT-EEEEEESSSEEEEEEEEEEESS.EEEEEEEEEEE---SSSS CS
  Methyltrans_RNA   2 sltdeeahHlvkVlRlkegdeiklfdgdgkeyeaeieeiskk.kvtvkilekeeenkespe 61 
                      ++++e + Hl  VlRl+ g +i +    gk ++ e+e+ +   +v+ ki++ke +++++++
       EEA20173.1 212 NIQKESTLHL--VLRLRGGMQIFVKTLTGKTITLEVESSDTIdNVKSKIQDKEGIPPDQQR 270
                      5788999999..*************************998751557778777777776655 PP

>> DUF3861  Domain of Unknown Function with PDB structure (DUF3861)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.0     0.022        14      19      59 ..       9      49 ..       5      57 .. 0.86
   2 ?    6.1   0.0      0.02        13      19      59 ..      85     125 ..      77     133 .. 0.87
   3 ?    6.1   0.0      0.02        13      19      59 ..     161     201 ..     153     209 .. 0.87
   4 ?    6.0   0.0     0.021        13      19      59 ..     237     277 ..     229     281 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.022
     DUF3861 19 eekpleFeaenhdDilkiverlkkkedldadeaaalavglk 59
                + k++++e+e++d i ++  ++++ke++ +d+++ +  g +
  EEA20173.1  9 TGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQ 49
                5579*************************999887776665 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.02
     DUF3861  19 eekpleFeaenhdDilkiverlkkkedldadeaaalavglk 59 
                 + k++++e+e++d i ++  ++++ke++ +d+++ +  g +
  EEA20173.1  85 TGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQ 125
                 5579*************************999887776665 PP

  == domain 3  score: 6.1 bits;  conditional E-value: 0.02
     DUF3861  19 eekpleFeaenhdDilkiverlkkkedldadeaaalavglk 59 
                 + k++++e+e++d i ++  ++++ke++ +d+++ +  g +
  EEA20173.1 161 TGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQ 201
                 5579*************************999887776665 PP

  == domain 4  score: 6.0 bits;  conditional E-value: 0.021
     DUF3861  19 eekpleFeaenhdDilkiverlkkkedldadeaaalavglk 59 
                 + k++++e+e++d i ++  ++++ke++ +d+++ +  g +
  EEA20173.1 237 TGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQ 277
                 5579*************************999887766655 PP

>> DUF2870  Protein of unknown function (DUF2870)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.0     0.046        30       3      25 ..      43      65 ..      41      76 .. 0.80
   2 ?    5.1   0.0     0.046        30       3      25 ..     119     141 ..     117     152 .. 0.80
   3 ?    5.1   0.0     0.046        30       3      25 ..     195     217 ..     193     228 .. 0.80
   4 ?    5.0   0.0     0.048        31       3      25 ..     271     293 ..     269     303 .. 0.79

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.046
     DUF2870  3 lWwagkelqrgkklsdyvGkNek 25
                l +agk+l++g++lsdy  + e 
  EEA20173.1 43 LIFAGKQLEDGRTLSDYNIQKES 65
                789*************9766555 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.046
     DUF2870   3 lWwagkelqrgkklsdyvGkNek 25 
                 l +agk+l++g++lsdy  + e 
  EEA20173.1 119 LIFAGKQLEDGRTLSDYNIQKES 141
                 789*************9766555 PP

  == domain 3  score: 5.1 bits;  conditional E-value: 0.046
     DUF2870   3 lWwagkelqrgkklsdyvGkNek 25 
                 l +agk+l++g++lsdy  + e 
  EEA20173.1 195 LIFAGKQLEDGRTLSDYNIQKES 217
                 789*************9766555 PP

  == domain 4  score: 5.0 bits;  conditional E-value: 0.048
     DUF2870   3 lWwagkelqrgkklsdyvGkNek 25 
                 l +agk+l++g++lsdy  + e 
  EEA20173.1 271 LIFAGKQLEDGRTLSDYNIQKES 293
                 789*************9765555 PP

>> ACT_5  ACT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.1     0.018        12      34      53 ..      11      30 ..       1      31 [. 0.84
   2 ?    6.1   0.0     0.016        10      33      53 ..      86     106 ..      76     107 .. 0.82
   3 ?    6.1   0.0     0.016        10      33      53 ..     162     182 ..     152     183 .. 0.82
   4 ?    6.1   0.0     0.016        10      33      53 ..     238     258 ..     228     259 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.018
       ACT_5 34 vrieltVesersvelLsnQl 53
                 +i+l+Ves+++++++ +++
  EEA20173.1 11 KTITLEVESSDTIDNVKSKI 30
                589*************9998 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.016
       ACT_5  33 tvrieltVesersvelLsnQl 53 
                   +i+l+Ves+++++++ +++
  EEA20173.1  86 GKTITLEVESSDTIDNVKSKI 106
                 468**************9998 PP

  == domain 3  score: 6.1 bits;  conditional E-value: 0.016
       ACT_5  33 tvrieltVesersvelLsnQl 53 
                   +i+l+Ves+++++++ +++
  EEA20173.1 162 GKTITLEVESSDTIDNVKSKI 182
                 468**************9998 PP

  == domain 4  score: 6.1 bits;  conditional E-value: 0.016
       ACT_5  33 tvrieltVesersvelLsnQl 53 
                   +i+l+Ves+++++++ +++
  EEA20173.1 238 GKTITLEVESSDTIDNVKSKI 258
                 468**************9998 PP

>> Big_7  Bacterial Ig domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0     0.081        52      13      42 ..       7      34 ..       6      54 .. 0.81
   2 ?    4.7   0.0     0.081        52      13      42 ..      83     110 ..      82     130 .. 0.81
   3 ?    4.7   0.0     0.081        52      13      42 ..     159     186 ..     158     206 .. 0.81
   4 ?    4.7   0.0     0.081        52      13      42 ..     235     262 ..     234     282 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.081
                -EBTSEEEEEEEEE-SS-EEEEEEEETTEE CS
       Big_7 13 tvsggtvtisasAsddggvskVefyvdgtl 42
                t++g+t+t++++ sd   +++V+  +++++
  EEA20173.1  7 TLTGKTITLEVESSDT--IDNVKSKIQDKE 34
                5678899999999998..888888877765 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.081
                 -EBTSEEEEEEEEE-SS-EEEEEEEETTEE CS
       Big_7  13 tvsggtvtisasAsddggvskVefyvdgtl 42 
                 t++g+t+t++++ sd   +++V+  +++++
  EEA20173.1  83 TLTGKTITLEVESSDT--IDNVKSKIQDKE 110
                 5678899999999998..888888877765 PP

  == domain 3  score: 4.7 bits;  conditional E-value: 0.081
                 -EBTSEEEEEEEEE-SS-EEEEEEEETTEE CS
       Big_7  13 tvsggtvtisasAsddggvskVefyvdgtl 42 
                 t++g+t+t++++ sd   +++V+  +++++
  EEA20173.1 159 TLTGKTITLEVESSDT--IDNVKSKIQDKE 186
                 5678899999999998..888888877765 PP

  == domain 4  score: 4.7 bits;  conditional E-value: 0.081
                 -EBTSEEEEEEEEE-SS-EEEEEEEETTEE CS
       Big_7  13 tvsggtvtisasAsddggvskVefyvdgtl 42 
                 t++g+t+t++++ sd   +++V+  +++++
  EEA20173.1 235 TLTGKTITLEVESSDT--IDNVKSKIQDKE 262
                 5678899999999998..888888877765 PP

>> UDP-g_GGTase  UDP-glucose:Glycoprotein Glucosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0       2.7   1.7e+03      81      99 ..       2      20 ..       1      27 [. 0.82
   2 ?    6.8   0.0     0.011       7.1      52     100 ..      49      97 ..      48     104 .. 0.84
   3 ?    6.8   0.0     0.011       7.1      52     100 ..     125     173 ..     124     180 .. 0.84
   4 ?    6.8   0.0     0.011       7.1      52     100 ..     201     249 ..     200     256 .. 0.84

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 2.7
                  EEEE-STT-EEE--EEEE- CS
  UDP-g_GGTase 81 evvltsfegktlyprvkrk 99
                  ++++++++gkt++++v+  
    EEA20173.1  2 QIFVKTLTGKTITLEVESS 20
                  689999******9999875 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.011
                   EE-TTHHHHHEEEEE--SS-S--TT----EEEE-STT-EEE--EEEE-T CS
  UDP-g_GGTase  52 elregrssdiyeiesvgaeglsspkdegkevvltsfegktlyprvkrkp 100
                   +l++gr+ + y+i++ ++ +l  + + g ++++++++gkt++++v+  +
    EEA20173.1  49 QLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSD 97 
                   5889**********99999865555679***************998765 PP

  == domain 3  score: 6.8 bits;  conditional E-value: 0.011
                   EE-TTHHHHHEEEEE--SS-S--TT----EEEE-STT-EEE--EEEE-T CS
  UDP-g_GGTase  52 elregrssdiyeiesvgaeglsspkdegkevvltsfegktlyprvkrkp 100
                   +l++gr+ + y+i++ ++ +l  + + g ++++++++gkt++++v+  +
    EEA20173.1 125 QLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSD 173
                   5889**********99999865555679***************998765 PP

  == domain 4  score: 6.8 bits;  conditional E-value: 0.011
                   EE-TTHHHHHEEEEE--SS-S--TT----EEEE-STT-EEE--EEEE-T CS
  UDP-g_GGTase  52 elregrssdiyeiesvgaeglsspkdegkevvltsfegktlyprvkrkp 100
                   +l++gr+ + y+i++ ++ +l  + + g ++++++++gkt++++v+  +
    EEA20173.1 201 QLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSD 249
                   5889**********99999865555679***************998765 PP

>> DUF969  Protein of unknown function (DUF969)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0     0.036        23      70     117 ..      32      79 ..      28      86 .. 0.88
   2 ?    4.3   0.0     0.036        23      70     117 ..     108     155 ..     104     162 .. 0.88
   3 ?    4.3   0.0     0.036        23      70     117 ..     184     231 ..     180     238 .. 0.88
   4 ?    1.4   0.0      0.28   1.8e+02      70     113 ..     260     303 ..     256     305 .] 0.90

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.036
      DUF969  70 eraGLkeraaklikkikkatagrlllvYllirelaaalglslgGhaqf 117
                 ++ G+    ++li   k++  gr l+ Y + +e +  l l+l G  q+
  EEA20173.1  32 DKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQI 79 
                 67888889999*****************************99887774 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.036
      DUF969  70 eraGLkeraaklikkikkatagrlllvYllirelaaalglslgGhaqf 117
                 ++ G+    ++li   k++  gr l+ Y + +e +  l l+l G  q+
  EEA20173.1 108 DKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQI 155
                 67888889999*****************************99887774 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.036
      DUF969  70 eraGLkeraaklikkikkatagrlllvYllirelaaalglslgGhaqf 117
                 ++ G+    ++li   k++  gr l+ Y + +e +  l l+l G  q+
  EEA20173.1 184 DKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQI 231
                 67888889999*****************************99887774 PP

  == domain 4  score: 1.4 bits;  conditional E-value: 0.28
      DUF969  70 eraGLkeraaklikkikkatagrlllvYllirelaaalglslgG 113
                 ++ G+    ++li   k++  gr l+ Y + +e +  l l+l G
  EEA20173.1 260 DKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRG 303
                 67888889999***************************999987 PP

>> YcgR_2  Flagellar protein YcgR
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.1     0.045        29       3      26 ..      10      33 ..       9      45 .. 0.89
   2 ?    4.9   0.1     0.045        29       3      26 ..      86     109 ..      85     121 .. 0.89
   3 ?    4.9   0.1     0.045        29       3      26 ..     162     185 ..     161     197 .. 0.89
   4 ?    4.9   0.1     0.045        29       3      26 ..     238     261 ..     237     273 .. 0.89

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.045
                TSEEEEEEEETTEEEEEEEEEEEE CS
      YcgR_2  3 Gdkveieiesgdgekryksrvvdi 26
                G+ +++e+es+d   ++ks+++d 
  EEA20173.1 10 GKTITLEVESSDTIDNVKSKIQDK 33
                899***********99******85 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.045
                 TSEEEEEEEETTEEEEEEEEEEEE CS
      YcgR_2   3 Gdkveieiesgdgekryksrvvdi 26 
                 G+ +++e+es+d   ++ks+++d 
  EEA20173.1  86 GKTITLEVESSDTIDNVKSKIQDK 109
                 899***********99******85 PP

  == domain 3  score: 4.9 bits;  conditional E-value: 0.045
                 TSEEEEEEEETTEEEEEEEEEEEE CS
      YcgR_2   3 Gdkveieiesgdgekryksrvvdi 26 
                 G+ +++e+es+d   ++ks+++d 
  EEA20173.1 162 GKTITLEVESSDTIDNVKSKIQDK 185
                 899***********99******85 PP

  == domain 4  score: 4.9 bits;  conditional E-value: 0.045
                 TSEEEEEEEETTEEEEEEEEEEEE CS
      YcgR_2   3 Gdkveieiesgdgekryksrvvdi 26 
                 G+ +++e+es+d   ++ks+++d 
  EEA20173.1 238 GKTITLEVESSDTIDNVKSKIQDK 261
                 899***********99******85 PP

>> DUF493  Protein of unknown function (DUF493)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0      0.22   1.4e+02      56      79 ..      12      35 ..       7      37 .. 0.89
   2 ?    3.1   0.0      0.22   1.4e+02      56      79 ..      88     111 ..      83     113 .. 0.89
   3 ?    3.1   0.0      0.22   1.4e+02      56      79 ..     164     187 ..     159     189 .. 0.89
   4 ?    3.1   0.0      0.22   1.4e+02      56      79 ..     240     263 ..     235     265 .. 0.89

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.22
      DUF493 56 tvtvrveseeqldalyqeLkahpr 79
                t+t++ves++ +d++ +++++ + 
  EEA20173.1 12 TITLEVESSDTIDNVKSKIQDKEG 35
                89**************99999876 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.22
      DUF493  56 tvtvrveseeqldalyqeLkahpr 79 
                 t+t++ves++ +d++ +++++ + 
  EEA20173.1  88 TITLEVESSDTIDNVKSKIQDKEG 111
                 89**************99999876 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.22
      DUF493  56 tvtvrveseeqldalyqeLkahpr 79 
                 t+t++ves++ +d++ +++++ + 
  EEA20173.1 164 TITLEVESSDTIDNVKSKIQDKEG 187
                 89**************99999876 PP

  == domain 4  score: 3.1 bits;  conditional E-value: 0.22
      DUF493  56 tvtvrveseeqldalyqeLkahpr 79 
                 t+t++ves++ +d++ +++++ + 
  EEA20173.1 240 TITLEVESSDTIDNVKSKIQDKEG 263
                 89**************99999876 PP

>> Raf1_HTH  Rubisco accumulation factor 1 helix turn helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.0      0.16     1e+02      34      55 ..      28      49 ..      26      52 .. 0.88
   2 ?    2.7   0.0      0.16     1e+02      34      55 ..     104     125 ..     102     128 .. 0.88
   3 ?    2.7   0.0      0.16     1e+02      34      55 ..     180     201 ..     178     204 .. 0.88
   4 ?    2.7   0.0      0.16     1e+02      34      55 ..     256     277 ..     254     280 .. 0.88

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.16
    Raf1_HTH 34 qeIfEaTGiepvqQnqliVaaq 55
                ++I ++ Gi p qQ ++  + q
  EEA20173.1 28 SKIQDKEGIPPDQQRLIFAGKQ 49
                6899***********9998877 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.16
    Raf1_HTH  34 qeIfEaTGiepvqQnqliVaaq 55 
                 ++I ++ Gi p qQ ++  + q
  EEA20173.1 104 SKIQDKEGIPPDQQRLIFAGKQ 125
                 6899***********9998877 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.16
    Raf1_HTH  34 qeIfEaTGiepvqQnqliVaaq 55 
                 ++I ++ Gi p qQ ++  + q
  EEA20173.1 180 SKIQDKEGIPPDQQRLIFAGKQ 201
                 6899***********9998877 PP

  == domain 4  score: 2.7 bits;  conditional E-value: 0.16
    Raf1_HTH  34 qeIfEaTGiepvqQnqliVaaq 55 
                 ++I ++ Gi p qQ ++  + q
  EEA20173.1 256 SKIQDKEGIPPDQQRLIFAGKQ 277
                 6899***********9998877 PP

>> ACT_4  ACT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0      0.23   1.5e+02      51      75 ..      12      36 ..       6      37 .. 0.86
   2 ?    3.1   0.0      0.22   1.4e+02      51      75 ..      88     112 ..      81     113 .. 0.86
   3 ?    3.1   0.0      0.22   1.4e+02      51      75 ..     164     188 ..     157     189 .. 0.86
   4 ?    3.1   0.0      0.22   1.4e+02      51      75 ..     240     264 ..     233     265 .. 0.86

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.23
       ACT_4 51 kitveVkdvehLsrviakLraipgV 75
                +it+eV++++ +++v  k++  +g+
  EEA20173.1 12 TITLEVESSDTIDNVKSKIQDKEGI 36
                69****************9976665 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.22
       ACT_4  51 kitveVkdvehLsrviakLraipgV 75 
                 +it+eV++++ +++v  k++  +g+
  EEA20173.1  88 TITLEVESSDTIDNVKSKIQDKEGI 112
                 69****************9976665 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.22
       ACT_4  51 kitveVkdvehLsrviakLraipgV 75 
                 +it+eV++++ +++v  k++  +g+
  EEA20173.1 164 TITLEVESSDTIDNVKSKIQDKEGI 188
                 69****************9976665 PP

  == domain 4  score: 3.1 bits;  conditional E-value: 0.22
       ACT_4  51 kitveVkdvehLsrviakLraipgV 75 
                 +it+eV++++ +++v  k++  +g+
  EEA20173.1 240 TITLEVESSDTIDNVKSKIQDKEGI 264
                 69****************9976665 PP

>> ORF11CD3  ORF11CD3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0      0.14        91      24      50 ..      53      79 ..      52      81 .. 0.93
   2 ?    3.3   0.0      0.14        91      24      50 ..     129     155 ..     128     157 .. 0.93
   3 ?    3.3   0.0      0.14        91      24      50 ..     205     231 ..     204     233 .. 0.93
   4 ?   -0.3   0.0       1.8   1.2e+03      24      37 ..     281     294 ..     280     302 .. 0.76

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.14
    ORF11CD3 24 GrgLsewKqkKpqltqkveeLeeklQl 50
                Gr+Ls++ ++K   +  v +L+  +Q+
  EEA20173.1 53 GRTLSDYNIQKESTLHLVLRLRGGMQI 79
                9***********999999999999997 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.14
    ORF11CD3  24 GrgLsewKqkKpqltqkveeLeeklQl 50 
                 Gr+Ls++ ++K   +  v +L+  +Q+
  EEA20173.1 129 GRTLSDYNIQKESTLHLVLRLRGGMQI 155
                 9***********999999999999997 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.14
    ORF11CD3  24 GrgLsewKqkKpqltqkveeLeeklQl 50 
                 Gr+Ls++ ++K   +  v +L+  +Q+
  EEA20173.1 205 GRTLSDYNIQKESTLHLVLRLRGGMQI 231
                 9***********999999999999997 PP

  == domain 4  score: -0.3 bits;  conditional E-value: 1.8
    ORF11CD3  24 GrgLsewKqkKpql 37 
                 Gr+Ls++ ++K   
  EEA20173.1 281 GRTLSDYNIQKEST 294
                 9******9988655 PP

>> ProRS-C_2  Prolyl-tRNA synthetase, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.1      0.16   1.1e+02       7      26 ..      17      36 ..      12      37 .. 0.80
   2 ?    3.1   0.1      0.16   1.1e+02       7      26 ..      93     112 ..      88     113 .. 0.80
   3 ?    3.1   0.1      0.16   1.1e+02       7      26 ..     169     188 ..     164     189 .. 0.80
   4 ?    3.1   0.1      0.16   1.1e+02       7      26 ..     245     264 ..     240     265 .. 0.80

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.16
                --....HHHHHHHCTTT-SE CS
   ProRS-C_2  7 envnlllenikeklsekkGv 26
                +++    +n+k k+++k G+
  EEA20173.1 17 VESSDTIDNVKSKIQDKEGI 36
                5567789**********997 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.16
                 --....HHHHHHHCTTT-SE CS
   ProRS-C_2   7 envnlllenikeklsekkGv 26 
                 +++    +n+k k+++k G+
  EEA20173.1  93 VESSDTIDNVKSKIQDKEGI 112
                 5567789**********997 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.16
                 --....HHHHHHHCTTT-SE CS
   ProRS-C_2   7 envnlllenikeklsekkGv 26 
                 +++    +n+k k+++k G+
  EEA20173.1 169 VESSDTIDNVKSKIQDKEGI 188
                 5567789**********997 PP

  == domain 4  score: 3.1 bits;  conditional E-value: 0.16
                 --....HHHHHHHCTTT-SE CS
   ProRS-C_2   7 envnlllenikeklsekkGv 26 
                 +++    +n+k k+++k G+
  EEA20173.1 245 VESSDTIDNVKSKIQDKEGI 264
                 5567789**********997 PP

>> Baculo_p48  Baculovirus P48 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.0     0.098        63     138     185 ..      64     111 ..      59     120 .. 0.89
   2 ?    2.3   0.0     0.098        63     138     185 ..     140     187 ..     135     196 .. 0.89
   3 ?    2.4   0.0     0.095        61     138     185 ..     216     263 ..     211     273 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.098
  Baculo_p48 138 ealssLdsslqeGWdiflrpilglilllyvllktdlkevdqdiineds 185
                 e+   L+  l+ G +if++++ g+ + l v     +++v + i +++ 
  EEA20173.1  64 ESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEG 111
                 56677899999*****************999999999****9999876 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.098
  Baculo_p48 138 ealssLdsslqeGWdiflrpilglilllyvllktdlkevdqdiineds 185
                 e+   L+  l+ G +if++++ g+ + l v     +++v + i +++ 
  EEA20173.1 140 ESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEG 187
                 56677899999*****************999999999****9999876 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.095
  Baculo_p48 138 ealssLdsslqeGWdiflrpilglilllyvllktdlkevdqdiineds 185
                 e+   L+  l+ G +if++++ g+ + l v     +++v + i +++ 
  EEA20173.1 216 ESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEG 263
                 56677899999*****************999999999****9999876 PP

>> Tash_PEST  Tash protein PEST motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   1.4    0.0097       6.2       7      16 ..      12      21 ..      12      21 .. 0.96
   2 ?    7.1   1.4    0.0097       6.2       7      16 ..      88      97 ..      88      97 .. 0.96
   3 ?    7.1   1.4    0.0097       6.2       7      16 ..     164     173 ..     164     173 .. 0.96
   4 ?    7.1   1.4    0.0097       6.2       7      16 ..     240     249 ..     240     249 .. 0.96

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0097
   Tash_PEST  7 TIpVEigSDe 16
                TI++E++S++
  EEA20173.1 12 TITLEVESSD 21
                9*******98 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0097
   Tash_PEST  7 TIpVEigSDe 16
                TI++E++S++
  EEA20173.1 88 TITLEVESSD 97
                9*******98 PP

  == domain 3  score: 7.1 bits;  conditional E-value: 0.0097
   Tash_PEST   7 TIpVEigSDe 16 
                 TI++E++S++
  EEA20173.1 164 TITLEVESSD 173
                 9*******98 PP

  == domain 4  score: 7.1 bits;  conditional E-value: 0.0097
   Tash_PEST   7 TIpVEigSDe 16 
                 TI++E++S++
  EEA20173.1 240 TITLEVESSD 249
                 9*******98 PP

>> Myosin_N  Myosin N-terminal SH3-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.2      0.49   3.1e+02      28      38 ..       5      15 ..       2      17 .. 0.86
   2 ?    2.8   0.0      0.17   1.1e+02      25      38 ..      78      91 ..      70      92 .. 0.79
   3 ?    2.8   0.0      0.17   1.1e+02      25      38 ..     154     167 ..     146     168 .. 0.79
   4 ?    2.8   0.0      0.17   1.1e+02      25      38 ..     230     243 ..     222     244 .. 0.79

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.49
                EEETTSEEEEE CS
    Myosin_N 28 VetedGktvtV 38
                V+t +Gkt t+
  EEA20173.1  5 VKTLTGKTITL 15
                9*******995 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.17
                EEEEEETTSEEEEE CS
    Myosin_N 25 kvtVetedGktvtV 38
                ++ V+t +Gkt t+
  EEA20173.1 78 QIFVKTLTGKTITL 91
                388********995 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.17
                 EEEEEETTSEEEEE CS
    Myosin_N  25 kvtVetedGktvtV 38 
                 ++ V+t +Gkt t+
  EEA20173.1 154 QIFVKTLTGKTITL 167
                 388********995 PP

  == domain 4  score: 2.8 bits;  conditional E-value: 0.17
                 EEEEEETTSEEEEE CS
    Myosin_N  25 kvtVetedGktvtV 38 
                 ++ V+t +Gkt t+
  EEA20173.1 230 QIFVKTLTGKTITL 243
                 388********995 PP

>> HAMP_N3  HAMP N-terminal domain 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0      0.31     2e+02      32      43 .]      20      31 ..      20      31 .. 0.89
   2 ?    1.6   0.0      0.31     2e+02      32      43 .]      96     107 ..      96     107 .. 0.89
   3 ?    1.6   0.0      0.31     2e+02      32      43 .]     172     183 ..     172     183 .. 0.89
   4 ?    1.6   0.0      0.31     2e+02      32      43 .]     248     259 ..     248     259 .. 0.89

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.31
                HHHHHHHHHHH- CS
     HAMP_N3 32 netieqvRgnLk 43
                ++ti++v+++++
  EEA20173.1 20 SDTIDNVKSKIQ 31
                59*******986 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.31
                 HHHHHHHHHHH- CS
     HAMP_N3  32 netieqvRgnLk 43 
                 ++ti++v+++++
  EEA20173.1  96 SDTIDNVKSKIQ 107
                 59*******986 PP

  == domain 3  score: 1.6 bits;  conditional E-value: 0.31
                 HHHHHHHHHHH- CS
     HAMP_N3  32 netieqvRgnLk 43 
                 ++ti++v+++++
  EEA20173.1 172 SDTIDNVKSKIQ 183
                 59*******986 PP

  == domain 4  score: 1.6 bits;  conditional E-value: 0.31
                 HHHHHHHHHHH- CS
     HAMP_N3  32 netieqvRgnLk 43 
                 ++ti++v+++++
  EEA20173.1 248 SDTIDNVKSKIQ 259
                 59*******986 PP

>> DMA  DMRTA motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.0      0.24   1.5e+02      14      24 ..      62      72 ..      60      76 .. 0.87
   2 ?    2.0   0.0      0.24   1.5e+02      14      24 ..     138     148 ..     136     152 .. 0.87
   3 ?    2.0   0.0      0.24   1.5e+02      14      24 ..     214     224 ..     212     228 .. 0.87
   4 ?    2.6   0.0      0.16     1e+02      14      25 ..     290     301 ..     288     305 .] 0.83

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.24
         DMA 14 hkrsvLelvLq 24
                +k s+L+lvL+
  EEA20173.1 62 QKESTLHLVLR 72
                899*******8 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.24
         DMA  14 hkrsvLelvLq 24 
                 +k s+L+lvL+
  EEA20173.1 138 QKESTLHLVLR 148
                 899*******8 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.24
         DMA  14 hkrsvLelvLq 24 
                 +k s+L+lvL+
  EEA20173.1 214 QKESTLHLVLR 224
                 899*******8 PP

  == domain 4  score: 2.6 bits;  conditional E-value: 0.16
         DMA  14 hkrsvLelvLqr 25 
                 +k s+L+lvL+ 
  EEA20173.1 290 QKESTLHLVLRL 301
                 89********96 PP

>> PI3K_p85B  PI3-kinase family, p85-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.1      0.15        96       1      18 [.      13      30 ..      13      33 .. 0.92
   2 ?    2.8   0.1      0.15        96       1      18 [.      89     106 ..      89     109 .. 0.92
   3 ?    2.8   0.1      0.15        96       1      18 [.     165     182 ..     165     185 .. 0.92
   4 ?    2.8   0.1      0.15        96       1      18 [.     241     258 ..     241     261 .. 0.92

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.15
   PI3K_p85B  1 itlrvsreatLseiKeeL 18
                itl+v+++ t++++K+++
  EEA20173.1 13 ITLEVESSDTIDNVKSKI 30
                89*************986 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.15
   PI3K_p85B   1 itlrvsreatLseiKeeL 18 
                 itl+v+++ t++++K+++
  EEA20173.1  89 ITLEVESSDTIDNVKSKI 106
                 89*************986 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.15
   PI3K_p85B   1 itlrvsreatLseiKeeL 18 
                 itl+v+++ t++++K+++
  EEA20173.1 165 ITLEVESSDTIDNVKSKI 182
                 89*************986 PP

  == domain 4  score: 2.8 bits;  conditional E-value: 0.15
   PI3K_p85B   1 itlrvsreatLseiKeeL 18 
                 itl+v+++ t++++K+++
  EEA20173.1 241 ITLEVESSDTIDNVKSKI 258
                 89*************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (305 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       183  (0.0102069); expected 358.6 (0.02)
Passed bias filter:                      136  (0.00758548); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                        30  (0.00167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              28  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2039.68
//
Query:       EEA20174.1  [L=772]
Description: C6 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0033   17.5   7.7     0.0072   16.4   7.7    1.6  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
       0.97    9.0  14.5        1.8    8.1  14.5    1.3  1  SR-25     Nuclear RNA-splicing-associated protein
          4    8.5   8.7         12    6.9   8.7    1.8  1  Pap_E4    E4 protein


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   7.7   1.2e-06    0.0072       1      34 [.     378     415 ..     378     418 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 1.2e-06
                 SS-HHHHHCT---STSSSS-HHHHHCT.....HHHCCCC CS
     Zn_clus   1 haCdnCrkkKvKCdakkPaCsnCkkln.....leCtfys 34 
                 +aC +C+  K  Cd++ P C+ C+ +      ++Ct ++
  EEA20174.1 378 RACLRCKFLKKTCDKGEP-CAGCQPSHarlwqVPCTRID 415
                 69****************.****8655444447777655 PP

>> SR-25  Nuclear RNA-splicing-associated protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1  14.5    0.0003       1.8      65     121 ..     301     366 ..     291     386 .. 0.36

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0003
       SR-25  65 ssssssssssssssssssssssdd.......rkkrgkkkdkkkkkkkkk..kkkkkekkkakekak 121
                 s s +ss+ssssss ssss    +       + k++ +k +k+ +  k    +k+  k+k+  k +
  EEA20174.1 301 SHSPRSSTSSSSSSPSSSSPPARKntrkspiAAKTAETKVRKQSQAGKPetTEKRIGKRKGPLKPD 366
                 222222222222222222222222122222333333333333332222232222223333333333 PP

>> Pap_E4  E4 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   8.7    0.0021        12      26      82 ..     291     344 ..     283     353 .. 0.65

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0021
      Pap_E4  26 rppkprpwaprkkkrrrlssdsdsssstspsspttkkseeespwtvtttgssvtlta 82 
                 + p++++++p +   + +ss+s+ssss+s+ssp+ +k++++sp+  +t +++v  + 
  EEA20174.1 291 PVPSKKVTSPSH---SPRSSTSSSSSSPSSSSPPARKNTRKSPIAAKTAETKVRKQS 344
                 444444566666...444455555556666666677777*******99999975444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (772 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       996  (0.0555525); expected 358.6 (0.02)
Passed bias filter:                      580  (0.0323498); expected 358.6 (0.02)
Passed Vit filter:                        76  (0.00423894); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.77u 0.33s 00:00:01.10 Elapsed: 00:00:00.49
# Mc/sec: 4729.47
//
Query:       EEA20175.1  [L=458]
Description: CaaX farnesyltransferase beta subunit Ram1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      1e-38  130.8  18.6    2.7e-09   36.6   1.1    6.3  6  Prenyltrans      Prenyltransferase and squalene oxidase repea
  ------ inclusion threshold ------
      0.012   14.8   0.0       0.65    9.0   0.0    2.5  3  SQHop_cyclase_N  Squalene-hopene cyclase N-terminal domain


Domain annotation for each model (and alignments):
>> Prenyltrans  Prenyltransferase and squalene oxidase repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.4   0.1   0.00081       7.3      32      44 .]      89     101 ..      75     101 .. 0.94
   2 !   22.3   0.4   8.9e-09     8e-05      14      44 .]     119     149 ..     118     149 .. 0.98
   3 !   16.2   0.0   7.2e-07    0.0064      15      43 ..     171     199 ..     165     200 .. 0.88
   4 !   36.6   1.1     3e-13   2.7e-09       8      44 .]     225     262 ..     222     262 .. 0.98
   5 !   24.0   0.2   2.6e-09   2.4e-05       2      40 ..     273     312 ..     272     316 .. 0.89
   6 !   33.9   0.0   2.1e-12   1.8e-08       3      43 ..     339     380 ..     337     381 .. 0.94

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.00081
                  HHHHHHHHHHHCT CS
  Prenyltrans  32 ytywalaaLallG 44 
                   +ywala+L llG
   EEA20175.1  89 MSYWALAGLTLLG 101
                  59*********98 PP

  == domain 2  score: 22.3 bits;  conditional E-value: 8.9e-09
                  SHTTS-BBSSTTSSBBHHHHHHHHHHHHHCT CS
  Prenyltrans  14 QnedGGwggrpgsesdtyytywalaaLallG 44 
                  Qn+ GG+gg  g  s+++ t+ a+++Lal+G
   EEA20175.1 119 QNPTGGFGGGHGQMSHLASTFPAVLSLALVG 149
                  99***************************98 PP

  == domain 3  score: 16.2 bits;  conditional E-value: 7.2e-07
                  HTTS-BBSSTTSSBBHHHHHHHHHHHHHC CS
  Prenyltrans  15 nedGGwggrpgsesdtyytywalaaLall 43 
                   +dGG+++  ++e d++++y+a+ + +ll
   EEA20175.1 171 EPDGGFQLVIDGEEDVRGAYCAMVTISLL 199
                  39**********99*********987776 PP

  == domain 4  score: 36.6 bits;  conditional E-value: 3e-13
                  HHHHHHSHTTS-BBSSTTS.SBBHHHHHHHHHHHHHCT CS
  Prenyltrans   8 efLlscQnedGGwggrpgs.esdtyytywalaaLallG 44 
                  e+L +cQ ++GG++g pg  e++++y++++la+L+++G
   EEA20175.1 225 EYLSRCQTYEGGLSGKPGAaEAHGAYAFCVLACLCIMG 262
                  7************************************8 PP

  == domain 5  score: 24.0 bits;  conditional E-value: 2.6e-09
                  HHHHHHHHHHHHSH.TTS-BBSSTTSSBBHHHHHHHHHHH CS
  Prenyltrans   2 dvekavefLlscQn.edGGwggrpgsesdtyytywalaaL 40 
                  d+  +v +L  +Q  ++GG++gr ++ +d++y+ w+  ++
   EEA20175.1 273 DIPLLVSWLSARQYaPEGGFSGRTNKLVDGCYSHWVGDCW 312
                  77789****************************9987666 PP

  == domain 6  score: 33.9 bits;  conditional E-value: 2.1e-12
                  HHHHHHHHHHHSH.TTS-BBSSTTSSBBHHHHHHHHHHHHHC CS
  Prenyltrans   3 vekavefLlscQn.edGGwggrpgsesdtyytywalaaLall 43 
                  +e +++++++c++ + GG+++ pg+++d+y++++ la+L+ +
   EEA20175.1 339 REGLARYIMNCCQnKNGGLRDKPGKHPDSYHSCYTLAGLSTI 380
                  899************************************975 PP

>> SQHop_cyclase_N  Squalene-hopene cyclase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.0   7.2e-05      0.65      38      92 ..      99     153 ..      82     163 .. 0.88
   2 ?    3.5   0.0    0.0035        32      47      80 ..     159     192 ..     152     216 .. 0.78
   3 ?   -2.6   0.0      0.26   2.4e+03     177     238 ..     392     452 ..     367     456 .. 0.46

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 7.2e-05
  SQHop_cyclase_N  38 flgeddeeeeekiakylrsqqredGgWelypggpgdlsttveaYlALkllGdspd 92 
                      +lged ++ +e++   +++ q++ Gg++  +g+ ++l  t  a l L l+G ++ 
       EEA20175.1  99 LLGEDVSKYRERVISTFTAAQNPTGGFGGGHGQMSHLASTFPAVLSLALVGGEEA 153
                      4588889999****************************************97765 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.0035
  SQHop_cyclase_N  47 eekiakylrsqqredGgWelypggpgdlsttvea 80 
                      + ++  +l + +++dGg++l+ +g+ d+  +  a
       EEA20175.1 159 RGAMWSWLGQLKEPDGGFQLVIDGEEDVRGAYCA 192
                      56778899999****************9865444 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 0.26
  SQHop_cyclase_N 177 revdldELfve..ppeevkyelrkekkalswtklflaldkvlkllerlplkplrkrAlrkaeew 238
                      ++ +++ +f+   + ++++ +++ e++ +++++++  +d+++ +   + +    ++Al    +w
       EEA20175.1 392 ATSRIEGIFASsfSWKSAPAKITIEEDDKASSDIIDKCDRLVAFHPIYTIPHKNAEAL---RRW 452
                      4555555555533333334444444444455556666666555544444444444443...444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (458 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       280  (0.0156172); expected 358.6 (0.02)
Passed bias filter:                      261  (0.0145574); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.49
# Mc/sec: 2821.10
//
Query:       EEA20176.1  [L=327]
Description: CaaX farnesyltransferase beta subunit Ram1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.4e-32  110.3  13.9    1.7e-09   37.3   1.1    5.2  5  Prenyltrans  Prenyltransferase and squalene oxidase repeat


Domain annotation for each model (and alignments):
>> Prenyltrans  Prenyltransferase and squalene oxidase repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    3.0   0.1    0.0049        87      28      44 .]       2      18 ..       1      18 [. 0.94
   2 !   16.8   0.0   2.3e-07    0.0042      15      43 ..      40      68 ..      34      69 .. 0.88
   3 !   37.3   1.1   9.4e-14   1.7e-09       8      44 .]      94     131 ..      91     131 .. 0.98
   4 !   24.6   0.2   8.3e-10   1.5e-05       2      40 ..     142     181 ..     141     185 .. 0.89
   5 !   34.6   0.0   6.5e-13   1.2e-08       2      43 ..     207     249 ..     206     250 .. 0.94

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.0049
                 BBHHHHHHHHHHHHHCT CS
  Prenyltrans 28 sdtyytywalaaLallG 44
                 s+++ t+ a+++Lal+G
   EEA20176.1  2 SHLASTFPAVLSLALVG 18
                 89*************98 PP

  == domain 2  score: 16.8 bits;  conditional E-value: 2.3e-07
                 HTTS-BBSSTTSSBBHHHHHHHHHHHHHC CS
  Prenyltrans 15 nedGGwggrpgsesdtyytywalaaLall 43
                  +dGG+++  ++e d++++y+a+ + +ll
   EEA20176.1 40 EPDGGFQLVIDGEEDVRGAYCAMVTISLL 68
                 39**********99*********987776 PP

  == domain 3  score: 37.3 bits;  conditional E-value: 9.4e-14
                  HHHHHHSHTTS-BBSSTTS.SBBHHHHHHHHHHHHHCT CS
  Prenyltrans   8 efLlscQnedGGwggrpgs.esdtyytywalaaLallG 44 
                  e+L +cQ ++GG++g pg  e++++y++++la+L+++G
   EEA20176.1  94 EYLSRCQTYEGGLSGKPGAaEAHGAYAFCVLACLCIMG 131
                  7************************************9 PP

  == domain 4  score: 24.6 bits;  conditional E-value: 8.3e-10
                  HHHHHHHHHHHHSH.TTS-BBSSTTSSBBHHHHHHHHHHH CS
  Prenyltrans   2 dvekavefLlscQn.edGGwggrpgsesdtyytywalaaL 40 
                  d+  +v +L  +Q  ++GG++gr ++ +d++y+ w+  ++
   EEA20176.1 142 DIPLLVSWLSARQYaPEGGFSGRTNKLVDGCYSHWVGDCW 181
                  77789****************************9987666 PP

  == domain 5  score: 34.6 bits;  conditional E-value: 6.5e-13
                  HHHHHHHHHHHHSH.TTS-BBSSTTSSBBHHHHHHHHHHHHHC CS
  Prenyltrans   2 dvekavefLlscQn.edGGwggrpgsesdtyytywalaaLall 43 
                   +e +++++++c++ + GG+++ pg+++d+y++++ la+L+ +
   EEA20176.1 207 SREGLARYIMNCCQnKNGGLRDKPGKHPDSYHSCYTLAGLSTI 249
                  5899************************************975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (327 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       316  (0.0176251); expected 358.6 (0.02)
Passed bias filter:                      282  (0.0157287); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.30s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 2280.30
//
Query:       EEA20177.1  [L=158]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
      0.046   14.4   0.0        0.1   13.3   0.0    1.6  1  dsrm       Double-stranded RNA binding motif
       0.17   12.2   0.3       0.38   11.0   0.3    1.6  1  DND1_DSRM  double strand RNA binding domain from DEAD END PRO


Domain annotation for each model (and alignments):
>> dsrm  Double-stranded RNA binding motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   1.2e-05       0.1       5      64 ..       7      62 ..       4      64 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.2e-05
                HHHHHHHTTSEEEEEEEEEESSTSSSEEEEEEEEETTEEEEEEEES.SHHHHHHHHHHHHH CS
        dsrm  5 LqeycqkkgkppnyeyvseegpphslpkFvvtvkvngklygsGvgs.nKKeAeqsAAedal 64
                L ++c++++++++ +   + +       +++ v+vn+++y + +   +   A  +AA++a+
  EEA20177.1  7 LASLCKRRHWTEPHYDSFQSST-----GYTCVVRVNNREYKTDSICeSEVMARENAAMRAY 62
                6679999997666664433333.....59***********977777699*********996 PP

>> DND1_DSRM  double strand RNA binding domain from DEAD END PROTEIN 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.3   4.3e-05      0.38       7      28 ..       7      29 ..       4      61 .. 0.67

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 4.3e-05
   DND1_DSRM  7 LeelCeknkwgsPvYelhs.eag 28
                L  lC+++ w  P+Y     ++g
  EEA20177.1  7 LASLCKRRHWTEPHYDSFQsSTG 29
                899************86553555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (158 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       454  (0.0253221); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.29s 00:00:00.71 Elapsed: 00:00:00.45
# Mc/sec: 1058.55
//
Query:       EEA20178.1  [L=427]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-26   93.0   0.4    2.2e-26   93.0   0.4    2.3  2  MCU       Mitochondrial calcium uniporter
     0.0075   15.8   0.5      0.016   14.8   0.5    1.4  1  DUF1281   Protein of unknown function (DUF1281)


Domain annotation for each model (and alignments):
>> MCU  Mitochondrial calcium uniporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.0   0.4   2.5e-30   2.2e-26      54     176 .]     231     354 ..     180     354 .. 0.90
   2 ?   -1.3   2.6      0.23     2e+03      66      87 ..     387     407 ..     357     424 .. 0.51

  Alignments for each domain:
  == domain 1  score: 93.0 bits;  conditional E-value: 2.5e-30
                 SSSHHHHHHHHHHHHH-SHHHHHHHHTCCCGGGCHHHHGGGHHHHHHHHTHHHHHHHT.TTS-S----HHHHHHHHHHHHHHHTTTHHHHGGCTTTCSS CS
         MCU  54 kkereleekleelreelepleekkeeidekAerrtrrllwagLallavqlgilarLTw.weysWDvmEPvtYfvtygtamafyaYflltkqeysyedvk 151
                  ++  l+ +l++l+++l++l   k+e+d+ A+r ++r++ +gL++++  + i+ +LT+   y WD mEPvtY v+++t+m +ya+fl++++e sy+++ 
  EEA20178.1 231 DRTYYLRMRLRKLSKSLKKLAIIKQECDMLAHRGAQRVALGGLGVMISWWYIVYKLTFeTPYGWDTMEPVTYLVSLSTLMGGYAWFLYHNREISYRSAL 329
                 55667888999***********************************************446************************************** PP

                 SSSSSSSTTT-SSS--SSHHHHHHH CS
         MCU 152 drqflkkfhklakkrkfDvekYneL 176
                 d ++ ++++kl++ r++D++ +++L
  EEA20178.1 330 DFTVNRRQQKLYQMRGIDLQVWESL 354
                 *******************998876 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.23
                 HHHH-SHHHHHHHHTCCCGGGC CS
         MCU  66 lreelepleekkeeidekAerr 87 
                 ++e l++ +++ke+ +e+Aer+
  EEA20178.1 387 VTEALKHERRQKEK-REEAERE 407
                 33333222221111.1222222 PP

>> DUF1281  Protein of unknown function (DUF1281)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.5   1.7e-06     0.016      65     125 ..     329     392 ..     321     404 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 1.7e-06
     DUF1281  65 LteeaieeierlyeqsglaavkWeslteak...realaallerksaDWlglvtledesdvetlW 125
                 L+ +  ++ ++ly+  g++ + Wesl e +   r+ ++++ e+  +DW  + + ede+ +e+l 
  EEA20178.1 329 LDFTVNRRQQKLYQMRGIDLQVWESLIEEAnalRREIKTVAEEYDVDWDERGDEEDERVTEALK 392
                 55566677899***************8754233889***************9999988877664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (427 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1797  (0.100229); expected 358.6 (0.02)
Passed bias filter:                      796  (0.0443973); expected 358.6 (0.02)
Passed Vit filter:                        76  (0.00423894); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.68u 0.29s 00:00:00.97 Elapsed: 00:00:00.46
# Mc/sec: 2784.43
//
Query:       EEA20179.1  [L=177]
Description: phosphotransmitter protein Ypd1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-13   50.0   0.1    4.7e-13   49.2   0.1    1.4  1  Hpt       Hpt domain
  ------ inclusion threshold ------
      0.014   15.2   0.6      0.022   14.6   0.6    1.5  1  DUF19     Domain of unknown function (DUF19)


Domain annotation for each model (and alignments):
>> Hpt  Hpt domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.2   0.1   5.3e-17   4.7e-13       6      78 ..      54     129 ..      50     136 .. 0.79

  Alignments for each domain:
  == domain 1  score: 49.2 bits;  conditional E-value: 5.3e-17
                 HHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHTTBHHHHHHHHHHHHHHH...HCTSCHHHHHHHHHHHHH CS
         Hpt   6 fleeaeelleqleqaldqedlqelaraaHtLKGsagmlGltelaelahelEdlld...ragelelepellealkal 78 
                 f+e+ae  +e++e+al+ +d+++l ++ H LKGs+++lGlt++++++++++++ +    ++e + +++++e +k+ 
  EEA20179.1  54 FFEQAEATFEKMEKALAKNDFDDLSQLGHFLKGSSATLGLTKVKDACEKIQHCKEdlpDEKEASEREKAIEGIKKT 129
                 9***************************************************443443333333333333355555 PP

>> DUF19  Domain of unknown function (DUF19)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.6   2.5e-06     0.022      36      84 ..      91     141 ..      57     173 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 2.5e-06
       DUF19  36 e.lkkfkksCeslksCfkslkCke.eeeakeakkkiekacdaveflskdfa 84 
                   l k+k++Ce++++C ++l  ++  +e ++a++ i+k+ ++v++ +k++a
  EEA20179.1  91 LgLTKVKDACEKIQHCKEDLPDEKeASEREKAIEGIKKTLKEVQVDYKEVA 141
                 34899***************9887677788888888888888887777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (177 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1286  (0.0717274); expected 358.6 (0.02)
Passed bias filter:                      558  (0.0311228); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.40
# Mc/sec: 1335.96
//
Query:       EEA20180.1  [L=177]
Description: phosphotransmitter protein Ypd1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-13   50.0   0.1    4.7e-13   49.2   0.1    1.4  1  Hpt       Hpt domain
  ------ inclusion threshold ------
      0.014   15.2   0.6      0.022   14.6   0.6    1.5  1  DUF19     Domain of unknown function (DUF19)


Domain annotation for each model (and alignments):
>> Hpt  Hpt domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.2   0.1   5.3e-17   4.7e-13       6      78 ..      54     129 ..      50     136 .. 0.79

  Alignments for each domain:
  == domain 1  score: 49.2 bits;  conditional E-value: 5.3e-17
                 HHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHTTBHHHHHHHHHHHHHHH...HCTSCHHHHHHHHHHHHH CS
         Hpt   6 fleeaeelleqleqaldqedlqelaraaHtLKGsagmlGltelaelahelEdlld...ragelelepellealkal 78 
                 f+e+ae  +e++e+al+ +d+++l ++ H LKGs+++lGlt++++++++++++ +    ++e + +++++e +k+ 
  EEA20180.1  54 FFEQAEATFEKMEKALAKNDFDDLSQLGHFLKGSSATLGLTKVKDACEKIQHCKEdlpDEKEASEREKAIEGIKKT 129
                 9***************************************************443443333333333333355555 PP

>> DUF19  Domain of unknown function (DUF19)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.6   2.5e-06     0.022      36      84 ..      91     141 ..      57     173 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 2.5e-06
       DUF19  36 e.lkkfkksCeslksCfkslkCke.eeeakeakkkiekacdaveflskdfa 84 
                   l k+k++Ce++++C ++l  ++  +e ++a++ i+k+ ++v++ +k++a
  EEA20180.1  91 LgLTKVKDACEKIQHCKEDLPDEKeASEREKAIEGIKKTLKEVQVDYKEVA 141
                 34899***************9887677788888888888888887777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (177 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1286  (0.0717274); expected 358.6 (0.02)
Passed bias filter:                      558  (0.0311228); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1154.28
//
Query:       EEA20181.1  [L=429]
Description: aspartate aminotransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      2e-91  306.9   0.0    2.4e-91  306.7   0.0    1.0  1  Aminotran_1_2  Aminotransferase class I and II


Domain annotation for each model (and alignments):
>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  306.7   0.0   1.3e-95   2.4e-91       2     363 .]      57     424 ..      56     424 .. 0.98

  Alignments for each domain:
  == domain 1  score: 306.7 bits;  conditional E-value: 1.3e-95
                    EEEESSSSSTTSTTSS.HHHHHHHHHHHHHHHHHTSTTST-BTTHHHHHHHHHHHHHC..TCTTCHTTGGEGEEEESHHHHHHHHHHHHHHHTTT- CS
  Aminotran_1_2   2 dvinLgsneylgdsgk.ptlpevakaekegalaggtlneygpidglpeleealakflg..rseklklkreaavvvgsGagaliealifllklnpgd 94 
                    ++inLg+++y++d+gk ++lp+v+ ae + + a+++ +ey  i+g   +  + a+++   +s +lk  r +  +++sG+gal+   +fl ++ pg+
     EEA20181.1  57 EKINLGVGAYRDDKGKpYVLPSVRAAEDK-IVASRQDKEYAAITGVGNFTAKAAELAYgaDSAALKDGRITITQTISGTGALRIGGAFLERFYPGS 151
                    79***************************.***************************99********************************99998 PP

                    E.EEEEESS-THHHHHHHHTTSEEEEEEBEETTTTEE-HHHHHHHHTTHHCTTETEEEEEEESS-TTT--B--HHHHHHHHHHHHHTTEEEEEEET CS
  Aminotran_1_2  95 e.ilvpdptyasyknilrlsggevvryplyseedfhldlealeealkeapegnkktkvilvesphNPtGtvatleeleklldlakkynlllfvDea 189
                    + i++p+pt+a+++ ++  sg+ev +y++y++++ +ld+e+l+e+lk ap+g++   ++l++++hNPtG+++t+e+++++ d++k+++++ f+D+a
     EEA20181.1 152 KkIFLPTPTWANHNAVFSDSGLEVGKYRYYNKDTIGLDFEGLIEDLKAAPKGSI---ILLHACAHNPTGVDPTPEQWRQISDVVKEKEHFAFFDMA 244
                    77****************************************************...*************************************** PP

                    TTTCBSSSS..HTHHHHGGSTTSTTEEEEEESSSTTSSGGG-EEEEEEEH.......HHHHHHHHHHHHHTS..SHHHHHHHHHHHHHHHHHHH.. CS
  Aminotran_1_2 190 Yagfvfgsl..davatranveeepnllivgslsKafGlaGeRvGyilgna.......avvsqlrklsrpfls..ssllqaavaaalsdallkqs.. 272
                    Y+gf++g+   da a r +ve++ n+++++s++K++Gl+GeR G++++++       +v sq+++l rp++s  + +++++++++l+d++lk++  
     EEA20181.1 245 YQGFASGNAdkDAFAPRYFVEQGHNIALCQSFAKNMGLYGERAGAFSIVCaseeekkRVESQIKILIRPLYSnpPIHGARIASTILNDPELKKQwl 340
                    *******997776666********************************999********************************************* PP

                    .HHHHHHHHHHHHHHHHHHHHHHS....TEEEECCSCSSEEEEEETHHCHHHHHHHHHHTCTEEEEEGGGGTSTTEEEEECTTS-HHHHHHHHHHH CS
  Aminotran_1_2 273 .eleemrqrlqkrrkelrdeLael....glkvlasqsgmflltdlsaetakelskkLleevgvyvtpgtsftvpgrlRitvAglteeeleelveal 363
                     e++ m++r++++r  l+++L++l    +++++++q+gmf +t+l++e      ++L++e+ vy t+        ++Ri+vAg t+ ++++l+e++
     EEA20181.1 341 aEVKGMADRIIEMRSLLKQNLEALgskhDWSHITNQIGMFAYTGLTPE----QMDVLAKEHSVYATK--------DGRISVAGITTGNVKRLAESI 424
                    *********************999************************....5677***********........*******************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (429 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       340  (0.0189637); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.23s 00:00:00.71 Elapsed: 00:00:00.39
# Mc/sec: 3297.97
//
Query:       EEA20182.1  [L=665]
Description: DNA binding protein SART-1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   6.8e-189  629.5  59.9   7.8e-189  629.3  59.9    1.0  1  SART-1          SART-1 family
  ------ inclusion threshold ------
       0.12   12.0   0.3       0.97    9.0   0.0    2.5  2  Phage_fiber_2   Phage tail fibre repeat
        3.1    8.3   6.4        0.3   11.5   0.8    2.1  2  Phage_lysozyme  Phage lysozyme


Domain annotation for each model (and alignments):
>> SART-1  SART-1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  629.3  59.9  1.3e-192  7.8e-189       1     631 []       4     629 ..       4     629 .. 0.85

  Alignments for each domain:
  == domain 1  score: 629.3 bits;  conditional E-value: 1.3e-192
      SART-1   1 slSiEEtNklRakLGLkPLe.........ddekkeekskkeddeeedaastledreaeaeenvkkaqeeeakkkkreelkerikkarekrereaklkgk 90 
                 +lSiE+ Nk+R++LGLkPL+         + +    k+ k++ +++++ stle+rea  ++n++k q+e+++++kr+e++++ik+ar+ ++r akl+gk
  EEA20182.1   4 ALSIEQNNKIRIALGLKPLPvpgaeapsgPVF----KEPKDSADKDEPGSTLESREALGYQNWQKLQDEAEARRKRQEKNAAIKRARDLAQRDAKLEGK 98 
                 59********************9997544333....334445556899*************************************************** PP

      SART-1  91 tLgedddedddakaWvkkskkrqkekkeaearakareldeeeeeekaaaaeytskdLaGlkVaHdlddfeegee.viLTLkDkgvlldee.eDeLeNvn 187
                 +Lg+    + d+kaW++++kk  k    ++++++ar+l ee  +e+++a eyt++dLaG+kVaH+l +fe+  + +iLTLkD++++++ee +DeLeN++
  EEA20182.1  99 GLGD-AGVELDTKAWLSQHKKMTK----KIEKERARKLAEE-LAERDRAVEYTAADLAGIKVAHELGAFEDAADgQILTLKDATIDENEEeGDELENLE 191
                 ****.679****************....999999***8776.46778899*********************7766***********999967******* PP

      SART-1 188 laekeklkknlelkkkkkkgYdpyeddedeekeksiLskYDeeidgkkkkksftLgdgsatsaeeree.keeikeklkkkklsLdltknaeasDyltee 285
                 ++++eklk++lelkkk +++Ydp++ d    + +siL++YDeeidgkk +k+ftL d+++++ eere+ ++++++ l+k+  +Ld+ ++a++sDy++ +
  EEA20182.1 192 MVDQEKLKEKLELKKK-RTAYDPMQAD----GTSSILAQYDEEIDGKK-RKHFTL-DAKGSTIEERETkRQHVSDMLNKQVFNLDIINEAPVSDYMDIS 283
                 ****************.66****7544....5799*********7777.99****.65555556566659***************************** PP

      SART-1 286 evkfKKpKkkkkkktRkkeeelkddddei.....kaesdedemdvdeeake....kekkrkaeeeveedsfvDDdeLqaaLakqRraalkkrkklrped 375
                 evk+KKpKkkk+k tR+k+    d+dd       +++s+ d+m+vd+++++    +   +  +++  ++sfvDD++Lqa+L  qRraa kkrk+lrpe+
  EEA20182.1 284 EVKIKKPKKKKAKTTRQKAI---DEDDIFplpdaTGTSNGDNMEVDSGQTAttngT---AAPQKKTYDTSFVDDEDLQASLVIQRRAAFKKRKQLRPEE 376
                 ****************9988...777744787766666689******988865321...23445667889***************************** PP

      SART-1 376 vakqlkeereeee.eekee...eeegglvldetseFvrnlgeieekeeekanrekeeesveeeeeeeeeeddeeededveealeeaeeeeeeeekeeee 470
                 +a+ql+ee+++++ e ++    +ee glv+detseFv+nl+++  +e + ++r  +++      ee++e+++ + ++d+e  ++ ae +ee    e   
  EEA20182.1 377 LARQLREESSQTPmEVDNGdgaDEEPGLVIDETSEFVSNLQRPVISE-RPTRRA-TTPP-----EEQDEDKEGSPEADME--MAGAEIKEE---GE--P 461
                 ************9555532345888****************988776.444444.3331.....2211222222222222..122222222...22..1 PP

      SART-1 471 esekeeskelsetgleeEptvskGlaaaLkllkqkglleete.e..eekqrerqkflaekrrr....eekrreererdrksgkedkqsarerekyarre 562
                 e+++  ++++s tgl+eE+t+++Gl+++L++l+q+gl+++++ +  ++ +r+rqkfl+ek +r    e+++r++rerdr++gk+d++sarere+yar+e
  EEA20182.1 462 EAADAGTAKISGTGLDEESTLDEGLGSTLAMLRQRGLVQRSDaAdmNSLHRDRQKFLQEKYKReaeaEKRARAQRERDRATGKLDRMSAREREEYARWE 560
                 222467789******************************6664358**************99999999999**************************** PP

      SART-1 563 nrqreqqeareaaeffekdYkPdvklkYvDefGreLtqKEAFkqLSHkFHGkgsGkkKtEKrlkKieee 631
                 n+qr+qqe+r++a+ f+++YkPdv+lkYvDe+Gr ++qKEAFk+LSH+FHGkgsGk+KtEK+lkKieee
  EEA20182.1 561 NKQRDQQESRQIADVFNREYKPDVQLKYVDEHGRLMNQKEAFKHLSHQFHGKGSGKMKTEKHLKKIEEE 629
                 ********************************************************************8 PP

>> Phage_fiber_2  Phage tail fibre repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.3      0.17     1e+03      27      38 ..      81      92 ..      80      95 .. 0.86
   2 ?    9.0   0.0   0.00016      0.97       2      18 ..     493     509 ..     492     510 .. 0.93

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.17
  Phage_fiber_2 27 AVKtayDkAnsa 38
                   A+K+a D+A + 
     EEA20182.1 81 AIKRARDLAQRD 92
                   89*******986 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00016
  Phage_fiber_2   2 ltqkGivqLssatdSts 18 
                    l q+G+vq+s+a d++s
     EEA20182.1 493 LRQRGLVQRSDAADMNS 509
                    78************998 PP

>> Phage_lysozyme  Phage lysozyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.5      0.79   4.7e+03      63      63 ..      96      96 ..      58     137 .. 0.46
   2 ?   11.5   0.8     5e-05       0.3      20      98 ..     568     646 ..     544     658 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.79
                    H CS
  Phage_lysozyme 63 v 63
                    +
      EEA20182.1 96 E 96
                    2 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 5e-05
                     EHHHHHHHHHHHHH..HHHHHHHHHTTSHHSSHHHHHHHHHHHHHHHHHHHHTTHHHHHHHHTTCHHHHHHHGGGSSEETC CS
  Phage_lysozyme  20 tkeeaagryekdlk..taerkikqyikvkdfepnqqdalvslafnvGkgGkrkastllralnagdwkkacsairkslkaGk 98 
                     +  ++a+++++++k     ++++++ +   ++++++   +s +f  + +Gk+k+ + l+++++++  +a+sa++ s   G 
      EEA20182.1 568 ESRQIADVFNREYKpdVQLKYVDEHGRL--MNQKEAFKHLSHQFHGKGSGKMKTEKHLKKIEEEKKREAMSALESSQHTGM 646
                     5678999999999983445889999995..****999999999999999**************************987775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (665 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2088  (0.116459); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.74u 0.31s 00:00:01.05 Elapsed: 00:00:00.47
# Mc/sec: 4215.91
//
Query:       EEA20183.1  [L=210]
Description: mitochondrial peptidyl-tRNA hydrolase Pth2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.6e-43  145.7   0.1    8.9e-43  145.3   0.1    1.2  1  PTH2         Peptidyl-tRNA hydrolase PTH2
  ------ inclusion threshold ------
       0.16   11.6   2.1       0.28   10.9   2.1    1.3  1  FAM176       FAM176 family
       0.41    9.4   5.1       0.73    8.6   5.1    1.3  1  Treacle      Treacher Collins syndrome protein Treacle
        2.7    6.0   5.4        3.3    5.7   5.4    1.1  1  DNA_pol_phi  DNA polymerase phi


Domain annotation for each model (and alignments):
>> PTH2  Peptidyl-tRNA hydrolase PTH2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.3   0.1     2e-46   8.9e-43       1     117 []      95     210 .]      95     210 .] 0.97

  Alignments for each domain:
  == domain 1  score: 145.3 bits;  conditional E-value: 2e-46
                 EEEEEEEESSSSS-HHHHHHHHHHHHHHHHHHHHHH..CHHHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHHHTT-SEEEEEETSSSSSSTTCEEEEE CS
        PTH2   1 lkmvlvvrkDLkmskGkiaaqcahAavalvkkllkes.nekellkeWeeegqkkivlkveseeeLlelaakakalglpaalirDagrtqiepgtkTvla 98 
                 +k+vlvvr+DL+m+kGkiaaqc+hA++a++k + +++ n + +lk+We+ gq+k++l+v+seee+l l+a+a +lgl+a++i+Dagrtqi++g++Tvl+
  EEA20183.1  95 VKLVLVVRTDLGMGKGKIAAQCSHATLACYKYYFSKApN-SPILKRWERGGQAKVALQVKSEEEMLVLQAQAMSLGLCARVIQDAGRTQIASGSRTVLG 192
                 599*****************************9998744.59********************************************************* PP

                 EEEEEHHHHHHHHTTSEB- CS
        PTH2  99 igPapksivdkvtgkLkll 117
                 +  +pk +vd+vtg+Lkll
  EEA20183.1 193 VL-GPKTVVDQVTGHLKLL 210
                 *9.9*************97 PP

>> FAM176  FAM176 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   2.1   6.2e-05      0.28      55      87 ..      50      81 ..      33     104 .. 0.46

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 6.2e-05
      FAM176 55 kkkkkklkeesekasededeeeeeeeedssese 87
                +++k+ +ke++ +  e+edee+eee+++++e +
  EEA20183.1 50 STAKRATKEKD-EIIEEEDEESEEEDSEEEEGD 81
                22222222221.122222222222222222222 PP

>> Treacle  Treacher Collins syndrome protein Treacle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   5.1   0.00016      0.73     474     516 ..      42      83 ..      35      97 .. 0.68

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00016
     Treacle 474 svpasGKavaaaaqaqkgpvkgseEedseSSeeeSdSeeeapa 516
                 s pa+ K   +a++a k+  +  eEed+eS ee+S+ ee   a
  EEA20183.1  42 SSPATTKRS-TAKRATKEKDEIIEEEDEESEEEDSEEEEGDGA 83 
                 567777766.444555555555788888888887776665444 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   5.4   0.00073       3.3     633     683 ..      58      82 ..      42     113 .. 0.49

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.00073
  DNA_pol_phi 633 gqaelfedededeeddeeeeeeddeededseedddeeesdedeededdedv 683
                  +++e+                          +++++ees+e++++e+++d 
   EEA20183.1  58 EKDEI--------------------------IEEEDEESEEEDSEEEEGDG 82 
                  11111..........................22222222222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (210 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1437  (0.0801495); expected 358.6 (0.02)
Passed bias filter:                      995  (0.0554967); expected 358.6 (0.02)
Passed Vit filter:                       129  (0.00719505); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.50u 0.29s 00:00:00.79 Elapsed: 00:00:00.47
# Mc/sec: 1352.99
//
Query:       EEA20184.1  [L=255]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (255 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       477  (0.0266049); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.47u 0.25s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 1825.47
//
Query:       EEA20185.1  [L=473]
Description: homocitrate synthase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.5e-78  264.0   0.3    2.2e-78  263.5   0.3    1.2  1  HMGL-like      HMGL-like
  ------ inclusion threshold ------
      0.085   12.7   0.0       0.43   10.4   0.0    2.0  2  Endonuc-BglII  Restriction endonuclease BglII


Domain annotation for each model (and alignments):
>> HMGL-like  HMGL-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  263.5   0.3   2.4e-82   2.2e-78       2     264 .]      64     323 ..      63     323 .. 0.97

  Alignments for each domain:
  == domain 1  score: 263.5 bits;  conditional E-value: 2.4e-82
                 -EEEE-TTTHHHHTSSS---HHHHHHHHHHHHHHT-SEE--TSGGGT.THHHHHHHS---TT-B..--EE-SSHHHHHHHHH....TT-SEEEEEEES- CS
   HMGL-like   2 vkivdttLRDGeqalkaalsveeklaiakaLdeagvdeiEvgfpaaseddfevvraiakavkkarilalvrarekdikaavealkgagakrvhvfiats 100
                 +ki+++tLR+Geq+++a +++e+k++iakaLde+gvd+iE++ p ase+++ +++ai+k + ka+il+++r++++d ++ave    +g++ v+v+i ts
  EEA20185.1  64 FKIIESTLREGEQFANAFFDTEKKIEIAKALDEFGVDYIELTSPCASEQSRLDCEAICKLGLKAKILTHIRCHMDDARVAVE----TGVDGVDVVIGTS 158
                 79********************************************************************************....************* PP

                 HHHHHHHHSSTHHHHHHHHHHHHHHHHHTT-ETTT-BTTTBS--HHHHHHHHHHHHHHT-SEEEEEETTS---HHHHHHHHHHHHHHS-.GGGEEEEEB CS
   HMGL-like 101 elhlkaklkkdreevakkaeeavkaarslgkdvelsledasrtdleflaevveaaeeaGatriniaDtvGvltPneaaelisalkervkdkvilsvHcH 199
                    ++++++kd+ ++++ a e++++++s+g++v++s ed+ r+dl +l+ ++ a++++G+ r+ iaDtvG+++P++++el++ l+ +v   +++++H+H
  EEA20185.1 159 SYLREHSHGKDITYIINTAIEVINFVKSKGIEVRFSSEDSFRSDLVDLLSIYSAVDQIGVHRVGIADTVGCASPRQVYELVRVLRGVVH--CDIETHFH 255
                 *****************************************************************************************..******** PP

                 -TTS-HHHHHHHHHHTT--EEEEBTTS--SSBBB-BHHHHHHHHHHTT...-B----HHHHHHHHHHH CS
   HMGL-like 200 ndlGlAvantlaAveaGadrvdgtvnGlGeraGnaaleelvaalealg...vdtgldlqklrsiaalv 264
                 nd+G+A+an+  A+eaGa+++d++v+G+Ger+G ++l  l+a + ++    v++++ l kl ++++lv
  EEA20185.1 256 NDTGCAIANAFCALEAGATHIDTSVLGIGERNGITPLGGLMARMMVQApeyVKSKYRLDKLKDLEDLV 323
                 *************************************776666666655***************9997 PP

>> Endonuc-BglII  Restriction endonuclease BglII
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   4.8e-05      0.43      12     116 ..      85     218 ..      77     282 .. 0.69
   2 ?   -0.9   0.0      0.14   1.3e+03      80      95 ..     321     336 ..     303     341 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 4.8e-05
  Endonuc-BglII  12 nelqeilevLkefrlslseikss...genksdvkkrikellaakgWeeekrika.........................eseeeneledildt... 76 
                    + + ei ++L+ef ++ +e++s+   ++ ++d ++  k  l+ak    + r ++                         e++  +++ +++ +   
     EEA20185.1  85 EKKIEIAKALDEFGVDYIELTSPcasEQSRLDCEAICKLGLKAKIL-THIRCHMddarvavetgvdgvdvvigtssylrEHSHGKDI-TYIINtai 178
                    5566899999999999999887621144555555555555555555.4444433455555566666666666666655544444444.34444011 PP

  Endonuc-BglII  77 hkvDfvKnrVaveiefnkkdqtyrDLlk.frlffeldlIdv 116
                    + ++fvK + ++e+ f + d + +DL+  ++++++ d+I v
     EEA20185.1 179 EVINFVKSK-GIEVRFSSEDSFRSDLVDlLSIYSAVDQIGV 218
                    456677766.9*****************8899999999965 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.14
  Endonuc-BglII  80 DfvKnrVaveiefnkk 95 
                    D+v + V+v+i fn++
     EEA20185.1 321 DLVAESVQVNIPFNNY 336
                    88999*********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (473 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       596  (0.0332422); expected 358.6 (0.02)
Passed bias filter:                      461  (0.0257125); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 3205.56
//
Query:       EEA20186.1  [L=574]
Description: sphinganine-1-phosphate aldolase BST1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.8e-19   67.3   0.0    1.6e-18   66.6   0.0    1.3  1  Pyridoxal_deC    Pyridoxal-dependent decarboxylase conserved 
    1.3e-05   24.3   0.0    7.1e-05   21.9   0.0    1.9  2  Aminotran_5      Aminotransferase class-V
     0.0025   17.2   0.0      0.004   16.5   0.0    1.2  1  DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family


Domain annotation for each model (and alignments):
>> Pyridoxal_deC  Pyridoxal-dependent decarboxylase conserved domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.6   0.0   2.7e-22   1.6e-18      14     373 ..     119     466 ..     113     468 .. 0.85

  Alignments for each domain:
  == domain 1  score: 66.6 bits;  conditional E-value: 2.7e-22
                    SSHH.HHHHHHHHHHCTGGGS--TTSTTBH.CSSH....HHHHHHHHHHHHHT-BTSSTTTSHHHHHHHHHHHHHHHHHTT--GGGTCCT-EEEEE CS
  Pyridoxal_deC  14 ekaesleqilediekilapgvttwhspefh.kllpagnslisllgdlLadainkngftweesPaltelevvvldwlaellglpeeflekegggvlq 108
                    ++  + eqi  +i ++       w++ ++  + +  g +l  l ++ +++ +  n +  +  P + ++e  ++ ++  l++ p     ++g gv +
     EEA20186.1 119 KEGWTSEQIRTEITQLTGMEHAKWEEGRVSgAVYHGGEDLSKLQTEAIGSFAVSNPLHPDVFPGIRKMESEIVAMVLSLFHGP-----TDGAGVTT 209
                    5555667777777777777777888888764788999**********************************************.....579***** PP

                    SSHHHHHHHHHHHHHHHHHHHHHHHTTTS.HHHHHCCEEEEEETTS-HHHHHHHHHHT-EEEEE--B.TTTBB-HHHHHHHHHHHHCTT.EEEEEE CS
  Pyridoxal_deC 109 vgssestllallAartkvikemkekgkelkeaeildklvlytsdqahssvekaalvlgvklrvipld.engklrgaalekaieedkekGlipffvv 203
                    +g++es+l+a lAar+k + e    +           + ++  + +h +  ka++++g+k+  +p+  +++k+   + +++i ++      ++  +
     EEA20186.1 210 SGGTESILMACLAARQKGRAERGITE-----------PEMVVPETVHAAFFKAGNYFGIKVHQVPCPaPDYKVHIPSVRRLINRNTVL---IVGSA 291
                    ***************99887655444...........669999**********************95267888899999999765443...44556 PP

                    EEBS-TTT-BB--HHHHHHHHHHCT-EEEEE-TTGGGGGGSGGGGG............GGTTGGGESEEEEECCCCTS--SS-EEEEESSCCGCHH CS
  Pyridoxal_deC 204 atlGttvlgaFddlkelgdicekydlwlHvDAAyaGsaficpeirh............llkgieradSitvnphKlllvlldcsalivkdkealqq 287
                    +++     g  dd+  l  +  ky+++lHvD   +   f+  + ++            ++++ + + Si+v  hK++ ++ + s+l++++++  ++
     EEA20186.1 292 PNF---PHGIVDDIPALSRLAVKYKIPLHVDCCLGS--FVIAFLKKagfpspyeeeggFDFRQPGVTSISVDTHKYGFAPKGNSVLLYRNRSYRNH 382
                    665...67899*********************9987..54444444455677778899***********************************999 PP

                    HH-EEECCCT.TTTTTSEECCCGSSSSSG.HHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT....TEEECSTTBSSEEEEE CS
  Pyridoxal_deC 288 alqleaeYLehedsdvaadlgtkaiplsr.rvrilklwfvlralGveglqnqirksvelakyleklirkde....rfeivaevelglVcFr 373
                    +  + +e+ +         +    i  sr    i+  w  l + G  g+ +  ++ +  ak++e  ir+d     + e++ ++++  V+F 
     EEA20186.1 383 QYFIFPEWTG-------GVYASPSIAGSRsGALIAGCWVSLMSIGESGYVASCHQIMGAAKQFETAIREDPilsaNLEVIGNPQVSVVAFA 466
                    9999999999.......6678899*****8899************************************9522224788889999999996 PP

>> Aminotran_5  Aminotransferase class-V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.9   0.0   1.2e-08   7.1e-05      52     176 ..     194     320 ..     183     326 .. 0.85
   2 ?   -0.5   0.0     0.076   4.5e+02     186     221 ..     346     382 ..     342     490 .. 0.71

  Alignments for each domain:
  == domain 1  score: 21.9 bits;  conditional E-value: 1.2e-08
                  HHHHHT-STGGGEEEESSHHHHHHHHHHHCCCC..-TTT...SEEEEETTSHGGGTHHHHHHHHHHTEEEEEEEB.ETTSCBEGGGHHHH--TTEEEE CS
  Aminotran_5  52 vaelinaeseeeiiftsGtteainlvalslars..lkpg...deivvteaehhanlvpwqelakrtgakvkvipl.deegeldldelekllnektklv 143
                  v  l++ +++   + tsG+te+i ++ l+++++   ++g    e+vv e+ h a +    ++ +  g+kv+ +p   ++ ++ +  ++ l+n +t l+
   EEA20186.1 194 VLSLFHGPTDGAGVTTSGGTESILMACLAARQKgrAERGitePEMVVPETVHAAFF----KAGNYFGIKVHQVPCpAPDYKVHIPSVRRLINRNTVLI 287
                  667788888888899************99988855333211157788888888888....999********998626799999*************** PP

                  EEESBETTTTEB--HHHHHHHHHHTT-EEEEE- CS
  Aminotran_5 144 aithvsnvtGtiqpveeigklakkkgalvlvDa 176
                    ++ +  +G++++++++ +la k+++ ++vD 
   EEA20186.1 288 VGSAPNFPHGIVDDIPALSRLAVKYKIPLHVDC 320
                  ********************************7 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.076
                  -HHHHTESEEEEETTT.TTSSTT-EEEEEEHHHHHTS CS
  Aminotran_5 186 dvkklgvDflafsghK.llgPtGiGvlyvrkellekl 221
                  d+++ gv  +++ +hK  ++P+G +vl  r++   + 
   EEA20186.1 346 DFRQPGVTSISVDTHKyGFAPKGNSVLLYRNRSYRNH 382
                  6666677677778899889999999999998765554 PP

>> DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   6.6e-07     0.004      40     146 ..     205     321 ..     189     326 .. 0.85

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 6.6e-07
                      EEEEESSHHHHHHHHHHH...TTTT......TT-EEEEESSS-THHHHHHHHTT-EEEEE-B-TTTSSB-GGGCGGG--TTEEEEEEB-...GG CS
  DegT_DnrJ_EryC1  40 haiavssGtaAlhlaLra...lgvg......pgdeVIvpsltFvatanavlelgakpvfvDvdpdtynidpaaieaaitertkaIlpVh...ly 121
                        +++s Gt+++++a  a      g       + e +vp +  +a  +a  + g k+  v   + +y +   +++++i+++t  I+        
       EEA20186.1 205 AGVTTSGGTESILMACLAarqK--GraergiTEPEMVVPETVHAAFFKAGNYFGIKVHQVPCPAPDYKVHIPSVRRLINRNTVLIVGSApnfPH 296
                      5799*******99997774551..2445556689************************************************999865411157 PP

                      GB---HHHHHHHHHHCT-EEEEE-T CS
  DegT_DnrJ_EryC1 122 GqvadmdalkaiaakhglkvieDaA 146
                      G v d++al ++a k+++++  D++
       EEA20186.1 297 GIVDDIPALSRLAVKYKIPLHVDCC 321
                      9999********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (574 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       328  (0.0182944); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.25s 00:00:00.87 Elapsed: 00:00:00.45
# Mc/sec: 3822.38
//
Query:       EEA20187.1  [L=98]
Description: 50S ribosomal protein L30, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.1e-12   45.2   0.3    8.2e-12   44.8   0.3    1.2  1  Ribosomal_L30  Ribosomal protein L30p/L7e


Domain annotation for each model (and alignments):
>> Ribosomal_L30  Ribosomal protein L30p/L7e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.8   0.3   4.6e-16   8.2e-12       2      51 .]       9      58 ..       8      58 .. 0.97

  Alignments for each domain:
  == domain 1  score: 44.8 bits;  conditional E-value: 4.6e-16
                   EEEE-S-STTS-HHHHHHHHHTT-SSTTEEEE--SSHHHHHHHHHCCCGE CS
  Ribosomal_L30  2 fVtrirsiigvppkvrktLqlLgLrkingtvvklntpsirGmLkkVkhlV 51
                   ++t+ rs+ig+p ++  +L++LgL+k+ +tv+ + t  ++G++ kVk+lV
     EEA20187.1  9 RITLMRSAIGLPLRQNMVLHALGLKKRMATVFYPVTRDVAGQIMKVKELV 58
                   8****************************999*****************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (98 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       406  (0.0226449); expected 358.6 (0.02)
Passed bias filter:                      344  (0.0191868); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.37u 0.24s 00:00:00.61 Elapsed: 00:00:00.39
# Mc/sec: 744.31
//
Query:       EEA20188.1  [L=755]
Description: Exocyst complex component Sec6, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
   1.1e-172  575.5   8.7   1.5e-172  575.0   8.7    1.2  1  Sec6        Exocyst complex component Sec6
  ------ inclusion threshold ------
      0.073   13.1   1.8       0.13   12.3   0.4    2.0  2  Laminin_II  Laminin Domain II
       0.11   11.4   8.3       0.35    9.8   2.5    2.5  2  Vps53_N     Vps53-like, N-terminal
        5.2    7.8   8.7       0.37   11.5   0.2    3.3  4  LprI        Lysozyme inhibitor LprI
        8.2    7.0   9.4         23    5.6   1.3    3.1  2  FadA        Adhesion protein FadA


Domain annotation for each model (and alignments):
>> Sec6  Exocyst complex component Sec6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  575.0   8.7  4.1e-176  1.5e-172       1     574 []     180     754 ..     180     754 .. 0.98

  Alignments for each domain:
  == domain 1  score: 575.0 bits;  conditional E-value: 4.1e-176
                 HHHHHHHHHHHHHHHHHHHHSTTSSSCHHHH....HHHHHHHHHHHHHCCCCS.----TT--...............-----HHHHHHHHHHHHHHHHC CS
        Sec6   1 fskvdkliekFdkllweiirslielvregntslvvrlvkiverEekeDeklealreltkkekdeedaanfr.....arrprnykkkflealeesveerf 94 
                 f+ +d ++++Fd+++++++++li l +++n+ +vvrl+ ++++Eek+De ++al+e++++++  e a++f+     +++ r+yk+kfl+a+e +++++f
  EEA20188.1 180 FQGLDSVVDWFDDHVGTACMNLIPLLQSDNNGMVVRLAIVIAKEEKNDEHVRALQEAQRDHE--ELANRFKsmnigPKTVRGYKEKFLQAIEFYAQNQF 276
                 899*********************************************************99..788999999999*********************** PP

                 TS--S---TT--HHHHH...HHHHHHHHHHHHCCCCCS-TTT-HHHHHHHHHHHHHHHHHHHHTTS-.--HHHHHHHHHHHHHHHH.HTTTSSHHHC.C CS
        Sec6  95 eeckekfseddkklellenldwlledLevVkdelaplfPpswkifktyvkiYhnklhdllqelvsse.leaedilailewvkkYskklsklnpelefkk 192
                 +++ke+f ed+++le  ++l+w+++dL++V++++++l+P++wki++ty+k+Yh+++hd+l+ lv+++ l+  ++lail+w  kY+kk+sk    l++k 
  EEA20188.1 277 DASKEDFLEDPDSLE--KSLKWFFNDLFTVQQGMQQLMPKRWKIYATYTKTYHKMMHDFLISLVDDPeLPPDNLLAILHWTPKYYKKMSK----LGWKS 369
                 ***********9999..9************************************************************************....99*** PP

                 CC---SS-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCT---...EESSSEE-CHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHH CS
        Sec6 193 kelkpllldekkeeLledYlklivkkmkeWldnllktEvkkftereepp.eededglyvlplpvdvfqmlaeqvdvaaeskqakilvgvleelsellks 290
                 ++l p +ld+++ eL++++ ++i + ++eW+d+++  ++k+  er++++ e+++dg+++++   d+++ml+eq+ +a++s++a++++g++++++++lk 
  EEA20188.1 370 ADLTPNVLDDREPELVRQWQSVILNAVDEWMDRIFAADKKALLERSSDAlETNSDGFFRTKMLGDMWRMLNEQIGAASASDRADVIEGIIDSMFRALKA 468
                 ************************************************99************************************************* PP

                 HHHHHHHHHHC-TTSTT.............HHHHHHHHHHHHHHHHH............HHHHHC..........---HHHHHHHHHHHHHHHHHHHHH CS
        Sec6 291 rqdawqelleeelkkymsvknnereeskpglveyliAlaNdqlkcad.........yaeslsskylelvsskye.eriteefeelldgfvdlskeaisa 379
                 rq awq++l+ee++ky++ ++  + e+ + l+++l+A+aNdq++c+d         y++++++++++lv+++y+ +r++ e+++l++g+vdls+++ s+
  EEA20188.1 469 RQVAWQTVLDEECAKYSNTSP-DQAEGLQALQDWLVAVANDQIACIDdneetgqvgYLTRFKRDIESLVTPNYMdDRASVELDALRNGYVDLSTHCLSQ 566
                 ****************66555.4556************************************************99*********************** PP

                 HCHHHHC.CTTCCCCHHHHTTTSSHHHHHHHHHHHHTTTTGGGS.S-HHHHHHHHHHHHHHHHHHHHHHHCSS----SHHHHHHHHHHHHHHHHHHHHH CS
        Sec6 380 lleiifn.DLkpalsklftkkWytgelmeqivetiedYlndykeylspelfevlleelldelvveYlralrkkklkfaakkqkkfaekikrDaeklydf 477
                 ++++if  D++ +l ++ft+kWy++ +++++++t+edY++dy ++l+p+l e+++eel+del+v+Yl+a+r++++kf  ++q+ f+ek+k+D+ +++ f
  EEA20188.1 567 FVNLIFVvDFRATLPEFFTSKWYGEFAIKRMTSTFEDYMSDYGSVLHPSLSEIFVEELSDELLVRYLSAIRNRGVKF--RRQDPFTEKFKDDILTVFAF 663
                 *****************************************************************************..******************** PP

                 HHHTT-..---CCCCTTHHHH...HHHH--SHHHHHHHHHHHHHS-TT--HHHHHHHHHCCSS-STCHHHHHHHHTT---SS----....-SSCCCS CS
        Sec6 478 feklgseedaaylkqklraielllelleledpdavplevetllesypdisedhveavlkaRkDldksevkelveqlkeikkevesavepprtifsrv 574
                 f+k+++ + ++++k+k+r +++l++lle+e++  +++++e l+++y+d++ ++veavl+aR+D+++s++ +++++++e+  +ve++    +ti+s+v
  EEA20188.1 664 FQKFPD-SFQTTIKNKWRLVDWLVRLLEAEKSAGIVNVYEALKTEYWDLQMSWVEAVLRARDDFERSMISSIKAKAAEL--NVERGL---ETIMSKV 754
                 ******.***********************************************************************9..567776...5888875 PP

>> Laminin_II  Laminin Domain II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.4   3.6e-05      0.13       3      58 ..      46     101 ..      44     110 .. 0.91
   2 ?   -1.7   0.1      0.75   2.7e+03      21      81 ..     111     170 ..     102     176 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 3.6e-05
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Laminin_II   3 elaaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankairdAr 58 
                 e ++e +e ++  l++l++ + ++++t+++l++i++  +e +e v+d++++ ++Ar
  EEA20188.1  46 EGLREQLENVQRSLAVLTEGQRQVSKTRDELQGIDKLCAESQETVEDFSQIDKLAR 101
                 567889999999**************************************999987 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.75
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--TTTTTGGGHHHHHHH CS
  Laminin_II  21 plsqnlentkeklseinrsveetnekvkdankairdArrsvkkLeklapqLldklkelkql 81 
                  +++ len  ++l ++++ ++e ++++++    +  A   +++L    ++ ld++++ k  
  EEA20188.1 111 MMKKGLENFDADLAKAEALLREDDDDLENQP-NLLKAHILISQLRDFRDEALDQIRRAKDS 170
                 5777788888888888888888877777654.45567777777777777777777766655 PP

>> Vps53_N  Vps53-like, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   2.5   9.8e-05      0.35       7     114 ..      10     116 ..       5     173 .. 0.86
   2 ?    4.7   0.3    0.0035        13     246     296 ..     288     338 ..     227     373 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 9.8e-05
     Vps53_N   7 leyinellpteqslanidelikklqeeikklddeiksvvraqanvgekgkealeeaqkaieelfqkikeikdkaekseemvkeitrdIkqLDiAKknlt 105
                 +  + e+l + + l+++  l  + q +   +d+++++  r+q++  +++   l+e q+ +++  ++++ i +  ++s+e+v++ + +I +L    +n  
  EEA20188.1  10 IPRLAEILRHPEDLDKLPALKLEYQRKKVAVDAQLREGLREQLENVQRSLAVLTEGQRQVSKTRDELQGIDKLCAESQETVEDFS-QIDKLARVQRNFE 107
                 566778888888889999998888999999****************************************************985.7999999999988 PP

     Vps53_N 106 tsiTtlkrL 114
                 + + + k L
  EEA20188.1 108 AVVMMKKGL 116
                 777665555 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.0035
     Vps53_N 246 dkldrRYawlkrklqdfeekykkiFpadWevaeRltveFckvTrkdlekil 296
                 d l++  +w+   l + ++  +++ p+ W++    t ++ k+ ++ l +++
  EEA20188.1 288 DSLEKSLKWFFNDLFTVQQGMQQLMPKRWKIYATYTKTYHKMMHDFLISLV 338
                 6788999*****************************999999999998887 PP

>> LprI  Lysozyme inhibitor LprI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.1      0.83     3e+03      30      59 ..      72     107 ..      33     110 .. 0.57
   2 ?   -1.4   0.2       1.1   3.8e+03      19      35 ..     115     131 ..      83     179 .. 0.57
   3 ?   -1.4   0.1         1   3.7e+03      43      59 ..     225     241 ..     214     284 .. 0.74
   4 ?   11.5   0.2    0.0001      0.37      19      75 ..     431     489 ..     412     510 .. 0.76

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.83
                 HHHHHH......HHHHHTT....HHHHHHHHHHHHH CS
        LprI  30 aykalk......eekekkavssearkaLkdaqraWi 59 
                 + ++l+      +e ++   + ++ ++L++ qr+++
  EEA20188.1  72 TRDELQgidklcAESQETVEDFSQIDKLARVQRNFE 107
                 333333444444222223556667777788888776 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 1.1
                 HHHHHHHHHHHHHHHHH CS
        LprI  19 alkaadaeLnkaykalk 35 
                  l++ da L ka + l+
  EEA20188.1 115 GLENFDADLAKAEALLR 131
                 44555555555554444 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 1
                 ....HHHHHHHHHHHHH CS
        LprI  43 vssearkaLkdaqraWi 59 
                 +++e  +aL++aqr+ +
  EEA20188.1 225 KNDEHVRALQEAQRDHE 241
                 45566777777777654 PP

  == domain 4  score: 11.5 bits;  conditional E-value: 0.0001
                 HHHHHHHHHHHHHHHHH.HHHHH..TT....HHHHHHHHHHHHHHHHHHHHHHHTTTS-T CS
        LprI  19 alkaadaeLnkaykalk.eekek..kavssearkaLkdaqraWikyRdaeCalakspake 75 
                  l ++ + Ln++  a++ +++++  +   +++++aLk+ q aW++  d eC + +s  ++
  EEA20188.1 431 MLGDMWRMLNEQIGAASaSDRADviEGIIDSMFRALKARQVAWQTVLDEEC-AKYSNTSP 489
                 56677778899998888655555788888999*******************.33333333 PP

>> FadA  Adhesion protein FadA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   1.5     0.015        54      26      98 ..      30      99 ..      25     100 .. 0.76
   2 ?    5.6   1.3    0.0064        23      23      74 ..     222     274 ..     214     282 .. 0.88

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.015
        FadA 26 kaeaaaaklakkkelkakieeklakleadsevrfykdeYkellkeyksllkelekeikekekkianfeklksl 98
                k+e +++k+a   +l++ ++e+l++++ +  v     e +  +++ ++ l+ ++k  +e ++++++f ++ +l
  EEA20188.1 30 KLEYQRKKVAVDAQLREGLREQLENVQRSLAV---LTEGQRQVSKTRDELQGIDKLCAESQETVEDFSQIDKL 99
                56777788888888888888888885443333...34556677888888889999999999999999999765 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0064
        FadA  23 ekakaeaaaaklakkkelkakieeklaklea.dsevrfykdeYkellkeyksl 74 
                 +++k ++ ++ l++ ++  +++ ++ + ++   + vr yk+++ + ++ y + 
  EEA20188.1 222 KEEKNDEHVRALQEAQRDHEELANRFKSMNIgPKTVRGYKEKFLQAIEFYAQN 274
                 678889999********************988999*********999988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (755 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       996  (0.0555525); expected 358.6 (0.02)
Passed bias filter:                      563  (0.0314016); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.74u 0.27s 00:00:01.01 Elapsed: 00:00:00.45
# Mc/sec: 5048.07
//
Query:       EEA20189.1  [L=363]
Description: endo-1,3(4)-beta-glucanase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-18   67.3   0.3      6e-18   64.9   0.3    1.9  1  Glyco_hydro_16  Glycosyl hydrolases family 16
    8.1e-06   24.5   3.1     0.0016   17.0   0.1    2.1  2  SKN1            Beta-glucan synthesis-associated protein (SKN


Domain annotation for each model (and alignments):
>> Glyco_hydro_16  Glycosyl hydrolases family 16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.9   0.3   6.7e-22     6e-18      13     170 ..     148     352 ..     136     359 .. 0.70

  Alignments for each domain:
  == domain 1  score: 64.9 bits;  conditional E-value: 6.7e-22
                     GEEEETTSEEEEEEEE.........EEEEEEEECCEESSE.....EEEEEEE.....---STTEEEEEEE...E.TGG...TSTTEEEEE.EEET CS
  Glyco_hydro_16  13 avsvengetltltldk.........esgsrikskksflyG.....kvearik.....aaksaGvvtafyl...s.sed...ekahdEiDi.EflG 80 
                     +v+ + g   t++l           ++++ri+sk++f+         ea+i+      ++++G+++af++   s   +   ++a++E+D+ E + 
      EEA20189.1 148 NVQLSGG--STIQLVPwadgsasggWTSGRIESKYTFTPAagvvtLAEAQIRfgtndISNKQGIWPAFWMlgdSlR-HgtsWPACGELDVlETVD 239
                     4444333..233333355667888899999999888875433444578888888888899**********764221.2467***********996 PP

                     T-TTE...EEEEEEBTTBSGE.EEEEETSS-TTTS-EEEEEEEE.......TTEEEEEETTEEEEEEESSHHH.HT.-......-EESEEEEEEE CS
  Glyco_hydro_16  81 ndtgk...vqtnvygkGkgkr.ekrlslwfdptedfHtYaieWt.......pdkikfyVDgkpvrtltkkeae.evky......Pqftpmkvavs 157
                      + +    v+ nvy  G  ++ + r      p++ +Ht+ i W+        ++i++y Dg+++ +++ ++   ++ +      P + +++vav+
      EEA20189.1 240 GQLTGygtVHCNVYPGGICNEpNGRSGNIGIPDQSWHTWRITWDrtswnwqTETITWYMDGRQFFQINGATIGnSDVWatlchnPLYFILNVAVG 334
                     65555588*********999864444446789999***9998651111111689**********99987776633322345678*********** PP

                     .EEEBS.HHHSSE-...E CS
  Glyco_hydro_16 158 .lwpgs.dwateqg...k 170
                       wpg  ++at +g    
      EEA20189.1 335 gGWPGYpNSATLGGygsM 352
                     *****9544444444444 PP

>> SKN1  Beta-glucan synthesis-associated protein (SKN1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.2   0.6     8e-05      0.71     208     229 ..     202     223 ..     126     230 .. 0.88
   2 !   17.0   0.1   1.7e-07    0.0016     377     450 ..     289     362 ..     242     363 .] 0.78

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 8e-05
        SKN1 208 gkgevsGlWPglWtmGnLgRpG 229
                 + ++ +G+WP++W++G+  R G
  EEA20189.1 202 DISNKQGIWPAFWMLGDSLRHG 223
                 457889**********988887 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 1.7e-07
        SKN1 377 dekgyitWfvgdektwtlkakalgpngnigqRliseepmsiilnlgisnnfa.aidwkele.fpatlriDyvRlyq 450
                  ++  itW+++ ++ ++++++++g++ ++ + ++ ++p++ iln+++   +  + + ++l  + +++++ yv ++q
  EEA20189.1 289 WQTETITWYMDGRQFFQINGATIGNS-DV-WATLCHNPLYFILNVAVGGGWPgYPNSATLGgYGSMMEVAYVAVFQ 362
                 34679**************9999865.55.7799*****************626677788779************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (363 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       293  (0.0163422); expected 358.6 (0.02)
Passed bias filter:                      219  (0.0122148); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2521.54
//
Query:       EEA20190.1  [L=199]
Description: antigenic cell wall galactomannoprotein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-22   80.2   0.0      2e-22   79.9   0.0    1.2  1  HsbA      Hydrophobic surface binding protein A


Domain annotation for each model (and alignments):
>> HsbA  Hydrophobic surface binding protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.9   0.0   1.1e-26     2e-22       2     119 ..      44     170 ..      43     171 .. 0.95

  Alignments for each domain:
  == domain 1  score: 79.9 bits;  conditional E-value: 1.1e-26
                 HHHHHHHHHHHHHHHHHHHHHHH--S...H...HHHHHHHHHHHHHHHHHHHHHHHTS----HHHHHHHHHHHHHCHHHHHHHHHHHHHTHHHHH.... CS
        HsbA   2 atvisdittistavtaldtavnafnG...g.asalpilsasnalvsaikkattdaqasapltdeealalaqavqtLepdvkaaldaliaKkpafd.... 92 
                 a +++di++i+++  +l+ ++ +++G   g +++++il ++  +++a+k++ +da++++ ++d+e+ ++ +a+++L p v ++l +++++k  f+    
  EEA20190.1  44 ALIVHDIEQIKKNAITLNYTIYNWGGgffGsFKLITILYQTGYVTNAMKTTLADAKNAHRFNDTESFNISHAFTELLPVVHDVLFWIMTRKIYFEygmf 142
                 5699********************99***99****************************************************************8866 PP

                 .HHT-HHHHHHHHHHHHHHHHHHHHHHH CS
        HsbA  93 .kagltslvlssLqdlkaasdaLsdalv 119
                   + lts+v+s L +++++s++++++++
  EEA20190.1 143 gLWSLTSTVRSILISQQDLSNQMGNEII 170
                 44466*******************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (199 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       536  (0.0298957); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.25s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1471.86
//
Query:       EEA20191.1  [L=438]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    9.4e-19   68.1   0.0    1.8e-18   67.2   0.0    1.5  1  AKAP7_NLS  AKAP7 2'5' RNA ligase-like domain


Domain annotation for each model (and alignments):
>> AKAP7_NLS  AKAP7 2'5' RNA ligase-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.2   0.0     1e-22   1.8e-18       2     176 ..      55     330 ..      54     349 .. 0.89

  Alignments for each domain:
  == domain 1  score: 67.2 bits;  conditional E-value: 1e-22
                 -EEEEEE---H...H.HHHHHHHHHHHHHH.............H-GG..GGGGB.--TT--EEEEEEE---SHHHHHHHHHHHHHHH............ CS
   AKAP7_NLS   2 thFlsiplnsn...k.lrkklekfqesvls.............klpg..ldeslfikpeklHlTllvlkLknkeeiaaakevLkevk............ 69 
                 thFl++pl s+   + l + l kf++++l                 +   d+++  +  + HlTl+v++L++ ++i++a+e Lk+++            
  EEA20191.1  55 THFLCLPLVSEtslPlLENSLLKFKHNLLLarkaggdhpsewlP--SlfPDSAI-RPLGTVHLTLGVMSLTSATRIEEAAEFLKSLNvdkilqevqsel 150
                 9*******8763335789*********99988888866665431..24245556.9999**************************************** PP

                 ......HHHHHHHTTS--EEEEEEEEEE.....TTTEEEEEE--SHHHHHHHHHHHHHHHHHHTTT--B--SS-......................... CS
   AKAP7_NLS  70 ......eeikdaldnkplslrlkGletfnddpakarVlYakveeesneekLqeladriikafeeaglvlekdkkk........................ 138
                       e+ ++ ++n+p+s++l+ l+ +  ++++a+VlYa+  +    ++L+ +a +i++af++ag+ +++  k+                        
  EEA20191.1 151 aspgtdESTIQGVNNNPISVSLEALGAL-PKAKAATVLYASPVDP--TSRLNPFAVKIRQAFVTAGFIEQDFMKQrpkktktrnqvsssennasntntn 246
                 *****9666667799*************.68888********954..7***********************99999*********************** PP

                 .............................---EEEEEEGGG-THHHHTT-.................-S--GG.GGGGGTT-EE CS
   AKAP7_NLS 139 .............................vklHaTlmnsrkrkkkqaksk.................esfdareilkqfkdfef 176
                                              + lHaTl+n+ ++ +  ++                    +fdar++l +++d+  
  EEA20191.1 247 tnnnghngaivaakaaeesiiqqkpklrpLFLHATLVNTIYAPGGRNAHHsshpgnkakrgrrhagpLTFDARGLLARYRDYYI 330
                 *****************************************998887777789999*********999***********99875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (438 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       773  (0.0431145); expected 358.6 (0.02)
Passed bias filter:                      440  (0.0245412); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.46
# Mc/sec: 2881.63
//
Query:       EEA20192.1  [L=214]
Description: mitochondrial chaperone Frataxin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.6e-35  120.0   0.0      7e-35  119.4   0.0    1.3  1  Frataxin_Cyay  Frataxin-like domain


Domain annotation for each model (and alignments):
>> Frataxin_Cyay  Frataxin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.4   0.0   3.9e-39     7e-35       1     106 [.      88     206 ..      88     208 .. 0.95

  Alignments for each domain:
  == domain 1  score: 119.4 bits;  conditional E-value: 3.9e-39
                    -HHHHHHHHHHHHHHHHHHHH.HHHHH--CTS.SEEEETTEEEEEETTS-EEEEEEEGGGTEEEEEES.SEEEEEEEET................T CS
  Frataxin_Cyay   1 lsdeeyhkladelldsleekleelaeeaeedeldveyssgvLtiefekkgtyvinkqppnkqIWlsspisgpkrfdyde...............kg 81 
                    lsd++yh++++++l+ l  ++e+++e+  +++ ++eys+gvL+i +++ gtyv+nkqppn+qIWlsspisgpkr+d++                +g
     EEA20192.1  88 LSDKDYHEVSEHYLNVLLGEVERVQEDG-SEI-EAEYSAGVLNIVVPSVGTYVLNKQPPNHQIWLSSPISGPKRYDWVIqgdqmhekqdtrgfiNG 181
                    6899***********************4.555.9*******************************************999**************99 PP

                    EEEETTTT-BHHHHHHHHHHHHHSS CS
  Frataxin_Cyay  82 eWiskrdgseLkelLeeelskalge 106
                    +Wi+ r+gs+L++lL++el+ +l e
     EEA20192.1 182 QWIYLRNGSNLTDLLNDELTLNLPE 206
                    *******************988766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (214 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       324  (0.0180713); expected 358.6 (0.02)
Passed bias filter:                      285  (0.015896); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.23s 00:00:00.66 Elapsed: 00:00:00.40
# Mc/sec: 1593.44
//
Query:       EEA20193.1  [L=87]
Description: CSL family zinc fnger-containing protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.8e-22   77.4   0.6    6.3e-22   77.1   0.6    1.2  1  zf-CSL    CSL zinc finger


Domain annotation for each model (and alignments):
>> zf-CSL  CSL zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.1   0.6   3.5e-26   6.3e-22       1      59 []      11      65 ..      11      65 .. 0.98

  Alignments for each domain:
  == domain 1  score: 77.1 bits;  conditional E-value: 3.5e-26
                EEEEGGGSEEETTTTEEEEEETTSSEEEEEHHHHHTT....--EEEETTSSEEEEEE-- CS
      zf-CSL  1 develedfefdeeeesyyypCRCgdeFelteedleegaegaevvvqCssCSLwikVkfa 59
                de+e+ed++fd++ ++y+ypC+Cgd+Fe+  + l++g    e ++ C+sCSL+i+V+f+
  EEA20193.1 11 DEIEIEDMTFDSNLQIYTYPCPCGDRFEIAIDSLRDG----EEIAVCPSCSLMIRVIFD 65
                89***********************************....****************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (87 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       420  (0.0234257); expected 358.6 (0.02)
Passed bias filter:                      310  (0.0172904); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.24s 00:00:00.62 Elapsed: 00:00:00.41
# Mc/sec: 640.58
//
Query:       EEA20194.1  [L=385]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.9e-10   40.9   1.2      4e-10   39.8   1.2    1.6  1  HAUS4      HAUS augmin-like complex subunit 4
    0.00031   20.8  18.5     0.0007   19.6  18.5    1.6  1  Mucin      Mucin-like glycoprotein
  ------ inclusion threshold ------
      0.011   13.8   8.7     0.0037   15.3   6.0    1.6  2  Dicty_REP  Dictyostelium (Slime Mold) REP protein
      0.021   14.8  15.3      0.039   13.9  15.3    1.4  1  DUF3439    Domain of unknown function (DUF3439)
      0.058   11.5   8.3       0.09   10.9   8.3    1.2  1  FSA_C      Fragile site-associated protein C-terminus
        1.7    7.6   8.9        1.1    8.3   4.1    2.1  2  FAM199X    Protein family FAM199X


Domain annotation for each model (and alignments):
>> HAUS4  HAUS augmin-like complex subunit 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.8   1.2   1.4e-13     4e-10     119     233 ..     259     383 ..     201     384 .. 0.81

  Alignments for each domain:
  == domain 1  score: 39.8 bits;  conditional E-value: 1.4e-13
       HAUS4 119 lLqklvkdhrLktqsdlDrlkkeyleakCeamllKlrvlelellldtYtkekvaalrkirekLeealeeeeaelqkaeerLrsYeilgkeFe....... 210
                  +  l++  +  + s+  +++++yl+   e m  K++v +le l+  Yt+e++aal++ + +L+e+l + e+ ++ a++ L++Y+ +g   +       
  EEA20194.1 259 RMVVLLERTKYGSLSRGTKARADYLATVAECMSYKVQVTKLETLSTIYTPENIAALENYSAHLRETLTQLEETRNIANQTLEEYDQVGTSKDnrkgktg 357
                 555555666666666777899*******************************************************************87552222222 PP

       HAUS4 211 ...elvreYsrlrkeienkkWaLkel 233
                    +++r+Y +l++e++  +  +k+l
  EEA20194.1 358 pmaDIARRYGDLVQEVDAVQREIKKL 383
                 22269*********999888777665 PP

>> Mucin  Mucin-like glycoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6  18.5   2.4e-07    0.0007      46      98 ..     128     195 ..      96     210 .. 0.53

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 2.4e-07
       Mucin  46 tttttttkppttttttt...............tasttittkttkattttttttttttateaPsdavtt 98 
                 + t  ++ p+ + t+t+                ++tt+tt+tt++ttttttttt+t++++ P+ a + 
  EEA20194.1 128 DKTIHALMPSVSETITShlnslrsiaevgnqaPTTTTTTTTTTTTTTTTTTTTTATSSSNIPTIAANQ 195
                 45555666666667776777777776654322111111222222222233333333333333332222 PP

>> Dicty_REP  Dictyostelium (Slime Mold) REP protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.3   6.0   1.3e-06    0.0037     169     294 ..      83     202 ..      78     251 .. 0.51
   2 ?   -2.2   0.0      0.24   7.3e+02     207     226 ..     296     315 ..     272     353 .. 0.57

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 1.3e-06
   Dicty_REP 169 klrtscakeklfv.aegfyknvDfisllslvhqikvdsqnrdEeklselYsLyPfvdlekeesdieqesiesentqrensqpskeknkttttttttttt 266
                 ++r s a   +f+ +++ + +  ++sl    ++  v +++ ++ +  ++  L P+v  e   ++++ +s+ s      ++ ++  +++ttttttttttt
  EEA20194.1  83 DIRESGAVIAMFLdTSPGLNEYKYVSLRDGQQEASVLNRDIENFHDKTIHALMPSVS-E--TITSHLNSLRSI----AEVGNQAPTTTTTTTTTTTTTT 174
                 566666655555413455666777777777777777666666666678888888888.3..344444443332....2233333333333333333333 PP

   Dicty_REP 267 tsqartrkrkaidddklsenqakekkkn 294
                 t++++t+   + +  +++ nq++ + k+
  EEA20194.1 175 TTTTTTTATSSSNIPTIAANQSRSRIKS 202
                 3333333333333344555444443333 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.24
   Dicty_REP 207 nrdEeklselYsLyPfvdle 226
                     e+ls++Y+      le
  EEA20194.1 296 VTKLETLSTIYTPENIAALE 315
                 33344444444444444444 PP

>> DUF3439  Domain of unknown function (DUF3439)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9  15.3   1.3e-05     0.039      45      78 ..     159     190 ..     124     201 .. 0.72

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.3e-05
     DUF3439  45 cpttttttttttttmpttttlptttkmsmvkvpl 78 
                  ptttttttttttt  tttt  ttt  s  ++p 
  EEA20194.1 159 APTTTTTTTTTTTTTTTTTT--TTTATSSSNIPT 190
                 57777777777777665555..555555555555 PP

>> FSA_C  Fragile site-associated protein C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   8.3     3e-05      0.09     542     610 ..     128     200 ..      91     217 .. 0.57

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 3e-05
       FSA_C 542 pklmsaakssleslqgsqdsi..aiattasavelndatsstiasaatasslsstk.stvti.vvstndskdga 610
                  k + a  +s++    s+ +   +ia+ ++ +   ++t++t+++++t++++++t  s+ +i ++++n+s+   
  EEA20194.1 128 DKTIHALMPSVSETITSHLNSlrSIAEVGNQAPTTTTTTTTTTTTTTTTTTTTTAtSSSNIpTIAANQSRSRI 200
                 4445555555554444443333555555555544444443333333333332222022333133556666544 PP

>> FAM199X  Protein family FAM199X
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.2     0.038   1.1e+02     246     285 ..      34      74 ..      22      90 .. 0.79
   2 ?    8.3   4.1   0.00037       1.1     208     290 ..     156     239 ..     132     247 .. 0.66

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.038
     FAM199X 246 srahsdsnls.saaerirdskkrskqrklqqkalrkrqlke 285
                 +ra  d      a+e +++ + r  +rk+ ++alr+  l +
  EEA20194.1  34 TRADGDIPERkVATEELKNLQIRNVKRKIIKQALRRACLED 74 
                 456555443348999********************988865 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.00037
     FAM199X 208 astsgvsaass..snasmvssassstasvgssaansaanisrahsdsnlssaaerirdskkrskqrklqqkalrkrqlkeqrqar 290
                 +  +  +++++  ++++  ++++++ta+ +s+  + aan sr+   s ls  a++i++ +  s q   +   lr+ q+ +   ar
  EEA20194.1 156 GNQAPTTTTTTttTTTTTTTTTTTTTATSSSNIPTIAANQSRSRIKSRLSIGAKKIQQPR-LSLQLDERITKLRRTQISDLPTAR 239
                 4333333333200333333444445555556667899******************98764.567777777778888877766666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (385 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1644  (0.091695); expected 358.6 (0.02)
Passed bias filter:                      607  (0.0338558); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.42
# Mc/sec: 2740.50
//
Query:       EEA20195.1  [L=779]
Description: transcription regulator BDF1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.9e-40  135.8   0.6    5.6e-19   68.0   0.1    2.6  2  Bromodomain     Bromodomain
    1.5e-18   66.7   2.4    2.9e-18   65.8   1.5    2.1  2  BET             Bromodomain extra-terminal - transcription re
  ------ inclusion threshold ------
      0.093   12.8   1.5       0.26   11.4   1.5    1.7  1  Sin3_corepress  Sin3 family co-repressor
       0.98    7.3   5.3        1.4    6.7   5.3    1.2  1  V_ATPase_I      V-type ATPase 116kDa subunit family
        2.9    8.1   5.6       0.34   11.1   1.1    1.7  2  DUF722          Protein of unknown function (DUF722)
        4.3    6.1   7.3        6.6    5.5   7.3    1.2  1  DUF3573         Protein of unknown function (DUF3573)


Domain annotation for each model (and alignments):
>> Bromodomain  Bromodomain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.6   0.1     1e-21   3.1e-18       4      82 ..     253     333 ..     250     335 .. 0.93
   2 !   68.0   0.1   1.9e-22   5.6e-19       1      83 [.     441     528 ..     441     529 .. 0.93

  Alignments for each domain:
  == domain 1  score: 65.6 bits;  conditional E-value: 1e-21
                  HHHHBHTTTCGGGGCSTT..-GCCSTTHHHH.SS---HHHHHHHHHTT--SSHHHHHHHHHHHHHHHHHHSHTTSHHHHHH CS
  Bromodomain   4 ilsellehklaepFlepv..dpeefpdyyavikkPldLstIkkklesnkYksladfeadlkllfsNarkyngegsviyela 82 
                   l++l++ ++a+ ++epv   + + p y+++i++P+dLstI++kl++n+Y+ +a++ ad+ l+  Na k+ng+++ +++  
   EEA20195.1 253 QLTNLKRSNDARFYREPVdpIKLNIPSYFTIITEPMDLSTIESKLKKNQYNAVAEIVADVDLMAGNAAKFNGPDHIVAQEG 333
                  57899999**********877899****************************************************99876 PP

  == domain 2  score: 68.0 bits;  conditional E-value: 1.9e-22
                  HHHHHHHBHTTT...CGGGGCSTT..-GCCSTTHHHH.SS---HHHHHHHHHTT--SSHHHHHHHHHHHHHHHHHHSHTTSHHHHHHH CS
  Bromodomain   1 lekilsellehk...laepFlepv..dpeefpdyyavikkPldLstIkkklesnkYksladfeadlkllfsNarkyngegsviyelae 83 
                  +++il+el + k    a+pF  pv     + p y++vikkP+dL t++ kl+ ++Y++ ++fead++l+++N+ k+n +g ++y++ +
   EEA20195.1 441 CQEILDELHKPKywaVASPFYFPVdpVALNIPTYHSVIKKPMDLYTVQTKLKAGQYENAKEFEADIRLMLKNCFKFNIPGDPTYVAGQ 528
                  8999999999999999********5555689****************************************************99866 PP

>> BET  Bromodomain extra-terminal - transcription regulation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0       4.6   1.4e+04      16      30 ..     296     310 ..     295     313 .. 0.85
   2 !   65.8   1.5   9.8e-22   2.9e-18       2      64 .]     638     701 ..     637     701 .. 0.98

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 4.6
         BET  16 kLpgeklgrvveIIq 30 
                 kL  ++ + v eI+ 
  EEA20195.1 296 KLKKNQYNAVAEIVA 310
                 799999999999985 PP

  == domain 2  score: 65.8 bits;  conditional E-value: 9.8e-22
         BET   2 mtyeeKkeLseeInkLpgeklgrvveIIqerepelq.sdedEiElDidaldddtLreLekyvkk 64 
                 +ty+eK+ +s++I+ L+++k++++++IIq++ p+l+  +e EiElDid+l++d+L  L k+vkk
  EEA20195.1 638 VTYAEKQMISNGISTLNDKKMQEALRIIQNNVPSLKgLQETEIELDIDELPNDVLVMLLKFVKK 701
                 8*************************************************************96 PP

>> Sin3_corepress  Sin3 family co-repressor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   1.5   8.8e-05      0.26      25      96 ..     529     596 ..     521     599 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 8.8e-05
  Sin3_corepress  25 lekevLNdewvsvptwasedsgsfkasrknqyeealfrcEderyelDmvieanrstiklleelakkiesmse 96 
                      ++ev+N++w+  + w ++++        nq   +  ++Ede  e D   e +++  +++ e+ k++e++++
      EEA20195.1 529 KCEEVFNNKWAAKARWVEQHD----PDSHNQSGSSDEESEDEDSEADEDQEKLQALQRQIAEMSKQVEAITQ 596
                     69**************55444....34668888888899********9999999999999999999887765 PP

>> V_ATPase_I  V-type ATPase 116kDa subunit family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   5.3   0.00048       1.4      60     177 ..     545     665 ..     499     699 .. 0.52

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.00048
  V_ATPase_I  60 eesleapeekeldeleeelekleeelkelnenleklkkelnelvelkavlekakefleeeeeeeeeeeseeeeee...keeeeeeeseeeeeeelleee 155
                 +e+++ +++++  + +ee e+ ++e  e +e+l++l+++  e+ ++ + +++ k+    +++++ +++s +++++   k ++++++ ++e+++ + +e+
  EEA20195.1 545 VEQHDPDSHNQSGSSDEESEDEDSEADEDQEKLQALQRQIAEMSKQVEAITQKKKKTPPASKKSGKSKSGKKDSKkgtKGDKKSKSGKSEKRHVTYAEK 643
                 333333333333344444444444444444444444444444443333333333322222111111111111111122333333333333444444445 PP

  V_ATPase_I 156 eelsfvaGvikrekveaferil 177
                 +++s+ + +++ +k+++  ri+
  EEA20195.1 644 QMISNGISTLNDKKMQEALRII 665
                 5566666666666666655555 PP

>> DUF722  Protein of unknown function (DUF722)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   1.1   0.00011      0.34      25      88 ..     541     600 ..     532     613 .. 0.82
   2 ?   -3.3   0.2       3.3   9.8e+03      41      57 ..     630     646 ..     615     682 .. 0.48

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00011
      DUF722  25 esryitrekvderiaygGtaenkesrvldkellikEeDkeliklkdqkellsellevlteeeke 88 
                 ++r++ ++  d +   +G+++ +es+  d++   +E+ ++l+ l++q   +s+ +e +t+++k+
  EEA20195.1 541 KARWVEQHDPDSHNQ-SGSSD-EESE--DEDSEADEDQEKLQALQRQIAEMSKQVEAITQKKKK 600
                 667877777776655.78888.7888..55555579999********************99876 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 3.3
      DUF722  41 gGtaenkesrvldkell 57 
                 +G +e +     +k+++
  EEA20195.1 630 SGKSEKRHVTYAEKQMI 646
                 44444333332333332 PP

>> DUF3573  Protein of unknown function (DUF3573)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   7.3    0.0022       6.6      24      98 ..     556     637 ..     545     669 .. 0.63

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0022
     DUF3573  24 sasyaesneqtsksnlidkelilklqkqikelqaeinhlketkns.......nesaqfttysskvedsklprslldnkeskd 98 
                 s s  e +e   +    d+e +  lq+qi+e+  +++ ++++k+         ++++     sk   ++  +s+++  e + 
  EEA20195.1 556 SGSSDEESEDEDSEADEDQEKLQALQRQIAEMSKQVEAITQKKKKtppaskkSGKSKSGKKDSKKGTKGDKKSKSGKSEKRH 637
                 455555555556567899**********************999874443333223333333333333333334444433333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (779 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2181  (0.121646); expected 358.6 (0.02)
Passed bias filter:                      731  (0.0407719); expected 358.6 (0.02)
Passed Vit filter:                       128  (0.00713927); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.91u 0.31s 00:00:01.22 Elapsed: 00:00:00.48
# Mc/sec: 4859.94
//
Query:       EEA20196.1  [L=851]
Description: small nucleolar ribonucleoprotein complex component (Utp5), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.8e-22   79.1   0.0    4.7e-22   78.3   0.0    1.4  1  Utp12      Dip2/Utp12 Family
      0.004   16.8   0.2       0.56    9.8   0.1    2.5  2  DUF3157    Protein of unknown function (DUF3157)
  ------ inclusion threshold ------
          2    7.7  44.8        1.7    8.0  26.9    2.4  2  SDA1       SDA1
        2.4    7.6  26.9        2.3    7.7   3.6    2.3  2  Drc1-Sld2  DNA replication and checkpoint protein


Domain annotation for each model (and alignments):
>> Utp12  Dip2/Utp12 Family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.3   0.0     1e-25   4.7e-22       1     105 [.     577     679 ..     577     681 .. 0.98

  Alignments for each domain:
  == domain 1  score: 78.3 bits;  conditional E-value: 1e-25
                 HHHHHHH.HHHSS-TTTHHHHHHCS-CTCHHHHHHHHHHHH.HTTTTHHHHHHHHHHHHHHHHHHHHHSH.HHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
       Utp12   1 ndeelleevlekippsdirltvlrLpssyvlkLLeflaerlaeksphlelllrwlkallrvHgsylvaspsdlvpaLrslqkslrerlktlskllglnl 99 
                 nd e+le+++++++++ ir+tv+rL s ++  L++ laer+a+++ +   ll w+++++++Hg++++++ +   ++++sl+k++++r ++l++ll l+ 
  EEA20196.1 577 NDSEMLESCFRTSDVNIIRTTVQRLNSALAGALIQRLAERMASRPGRYGHLLVWVQWTCVAHGGAIAGNTE-ILKRMTSLYKVMDQRSRSLPSLLLLK- 673
                 899*****************************************************************997.88************************. PP

                 HHHHHH CS
       Utp12 100 grLdyl 105
                 g+Ld+l
  EEA20196.1 674 GKLDML 679
                 *****9 PP

>> DUF3157  Protein of unknown function (DUF3157)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.8   0.1   0.00012      0.56      66     118 ..     338     404 ..     320     431 .. 0.68
   2 !    4.3   0.0     0.006        27     115     163 ..     544     592 ..     527     611 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00012
     DUF3157  66 aavattpvvkksva.............tliasalakpellkslaksGvkvslskakyed.grLgLtf 118
                 + + ++ ++ k+ a             + ++++ + pel    a++Gv+v++   +++d +   L+f
  EEA20196.1 338 QKARAKQMIRKADAilkilrpdtrkavSAVQVGFQGPELYIAWAEGGVNVIFERVRWQDqDTGDLVF 404
                 3333333333333333333334444458899**************************9964434443 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.006
     DUF3157 115 gLtfeltsqSsesvivvelevslyddsGellktekvtvWqaifRmaetY 163
                  L+  l+s+ ++ v ++   vsl     + lkt+++++ ++ fR ++  
  EEA20196.1 544 ALVPGLSSNTNQTVAQIPSGVSLSTVLTQALKTNDSEMLESCFRTSDVN 592
                 577789**************************************99964 PP

>> SDA1  SDA1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   9.9    0.0029        13      91     181 ..     427     531 ..     394     573 .. 0.54
   2 ?    8.0  26.9   0.00039       1.7      48     172 ..     681     824 ..     666     850 .. 0.44

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0029
        SDA1  91 eeedsddeddeedwevesdddseedseggwidvesdeeeieesdesedeeeeeeeeeekeekeeeeeeee..eeeeeeeeeeeeeekekkkk....... 180
                  +  s++  +e+++ ves   s ed+e +   ve+d   +++sd  ed ++ e+e ++k++ ++ +  +   ++++ +e + +e++++++++       
  EEA20196.1 427 GQRASKSHVNENSTIVESGLYS-EDVEMNDAHVEDDA--VSISD-AEDHSDIETETTQKRQTKKVNGVNGtsKDTDMQEAAAAEQDEDEEDEggeltfg 521
                 3444555666666666665555.77777767776665..45666.444444444444444333333332222222223333333222222224455556 PP

        SDA1 181 .........k 181
                          +
  EEA20196.1 522 elvqrssaiD 531
                 5555544440 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.00039
        SDA1  48 aemelrs.ekkakkfGeeevaegieGleLlekwkeeekkekre...................eeeedsddeddeedwevesdddseedseggwidvesd 126
                 a+++lr+  + ++k G ++ +e++e +  ++ +++++++ +r+                   +ee d+dde  +e   ++sd+d+   +eg+  + + d
  EEA20196.1 681 AQINLRQsMADSRKHGMDDGGESLEHITHYAGVSNDDSDAERRrkrkktlshiksksaldgaDEEADEDDEMADEVGGLASDSDE---EEGS--EEDMD 774
                 5666666666777888888877777777666666666555555566688887777666654322222223333333333333322...2222..22223 PP

        SDA1 127 ee.....eieesdesedeeeeeeeeeekeekeeeeeeee.....eeeeeeeeeeee 172
                 ee     +ie +++ +de++ee+ +e++ee++++++++      +     +e++ee
  EEA20196.1 775 EEigdmiDIEAEESLDDEDDEED-DEDEEEEDSDAASDMrdfiaD-----SEVDEE 824
                 33444443333332222222222.222222222222222222211.....111111 PP

>> Drc1-Sld2  DNA replication and checkpoint protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   3.6   0.00051       2.3     291     359 ..     436     509 ..     397     540 .. 0.68
   2 ?    5.4  15.4    0.0026        12     303     398 ..     692     807 ..     668     849 .. 0.62

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00051
   Drc1-Sld2 291 deldllremEaeeeqaeldd..vedsqa...seaeegrvrkkkgqkrttRrvkmkPvt.........eeeeededekknsede 359
                 +e +++ e   ++e+ e++d  ved+ +   ++++++  +   +qkr+t++v+    t         +         + ++de
  EEA20196.1 436 NENSTIVESGLYSEDVEMNDahVEDDAVsisDAEDHSDIETETTQKRQTKKVNGVNGTskdtdmqeaA---------AAEQDE 509
                 455555555555666666666666776677677778899**************998885555432221.........222222 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.0026
   Drc1-Sld2 303 eeqaeldd....vedsqa.......seaeegrvrkkkgqkrttRrvkmkPvteeeeededekknsedeldklpetqrkae................kld 374
                 + + ++dd    +    +        +++ +  ++++++k+t   +k k+    ++e+ de+++  de+  l+    ++e                + +
  EEA20196.1 692 SRKHGMDDggesL----EhithyagVSNDDSDAERRRKRKKTLSHIKSKSALDGADEEADEDDEMADEVGGLASDSDEEEgseedmdeeigdmidiEAE 786
                 4444455433330....13333333233333556667778899999999999999*****************999777778999888877766655555 PP

   Drc1-Sld2 375 delseredseededsdsdeesese 398
                 ++l+++ d+e+ded++++++   +
  EEA20196.1 787 ESLDDEDDEEDDEDEEEEDS---D 807
                 55522222222222222211...1 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (851 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1322  (0.0737353); expected 358.6 (0.02)
Passed bias filter:                      538  (0.0300073); expected 358.6 (0.02)
Passed Vit filter:                        76  (0.00423894); expected 17.9 (0.001)
Passed Fwd filter:                        32  (0.00178482); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.05u 0.35s 00:00:01.40 Elapsed: 00:00:00.52
# Mc/sec: 4921.82
//
Query:       EEA20197.1  [L=804]
Description: cell cycle regulatory protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.3e-10   39.5   6.4    0.00028   21.6   0.0    5.5  5  WD40         WD domain, G-beta repeat
    2.8e-05   24.3   0.3       0.78   10.1   0.0    3.7  3  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.31   2.7e+03      19      38 .]     301     319 ..     296     319 .. 0.65
   2 !    7.1   0.1    0.0012        11      12      38 .]     338     367 ..     323     367 .. 0.78
   3 ?    2.0   0.0     0.048   4.3e+02       9      23 ..     381     393 ..     371     400 .. 0.75
   4 !   21.6   0.0   3.1e-08   0.00028       5      36 ..     439     471 ..     436     473 .. 0.86
   5 !    6.8   0.1    0.0015        13       2      37 ..     610     648 ..     609     649 .. 0.75

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.31
                 ETTSSEEEEEETTSEEEEEE CS
        WD40  19 spdgawlasGsdDgtvriWd 38 
                 ++ +a+la +   gt+++W+
  EEA20197.1 301 CHTSALLAVAE-LGTIKLWS 319
                 55566665444.79*****5 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0012
                 SEEEEEEETTSSE...EEEEETTSEEEEEE CS
        WD40  12 svtslafspdgaw...lasGsdDgtvriWd 38 
                  vt+lafs+++     la+G++ g +++Wd
  EEA20197.1 338 EVTALAFSSSSGRksiLAAGTECGYIHLWD 367
                 399**98888888787999**********9 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.048
                 SSSSEEEEEEETTSS CS
        WD40   9 GHssvtslafspdga 23 
                 +H  vt++af p  +
  EEA20197.1 381 TH--VTCVAFKPTTT 393
                 67..*****999766 PP

  == domain 4  score: 21.6 bits;  conditional E-value: 3.1e-08
                 EEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS
        WD40   5 rtltGH.ssvtslafspdgawlasGsdDgtvri 36 
                   +++H + v+s+ +spd+++la+++dD+ + +
  EEA20197.1 439 ANISAHyTRVCSITWSPDNRYLATSGDDNICLL 471
                 56789*999***************998988876 PP

  == domain 5  score: 6.8 bits;  conditional E-value: 0.0015
                 EEEEEEESS.SSEEEEEEETTSSEE.EEEE..TTSEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawl.asGs..dDgtvriW 37 
                 ++++ ++ H   + ++af p ++ l a+G+   D+tv+++
  EEA20197.1 610 NHIHRFE-HsAAIKAVAFAPWQPTLlATGGgiTDCTVHFY 648
                 5677775.8455*****9999999726886455****987 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.1   0.1    0.0031        28       2      90 ..     299     389 ..     298     391 .. 0.69
   2 !   10.1   0.0   8.7e-05      0.78      36      72 ..     443     477 ..     418     490 .. 0.82
   3 !    4.7   0.0     0.004        36      37      91 ..     617     672 ..     596     673 .. 0.76

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0031
  ANAPC4_WD40   2 swcptmDLiAlatedgellvfRlngqrvwtl.....eedkedsevrsLaWkpd...gklLavaysdgevrlldaesgkvvhslsvksekavtclgWg 90 
                  s+c t  L+A+a   g +    l   +v++       +   + ev++La++ +    ++La +++ g ++l d    + + +++  ++  vtc+ ++
   EEA20197.1 299 SYCHTSALLAVAE-LGTI---KLWSTMVFKCvaefsVRWYIEDEVTALAFSSSsgrKSILAAGTECGYIHLWDTPRLRKIFTWRFMTH--VTCVAFK 389
                  6777777777663.2333...33334444444333545566789999999864211579***************99999999999988..9999875 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 8.7e-05
  ANAPC4_WD40  36 kedsevrsLaWkpdgklLavaysdgevrlldaesgkv 72 
                  ++  +v s+ W+pd++ La + +d+ + l+++++  +
   EEA20197.1 443 AHYTRVCSITWSPDNRYLATSGDDNICLLFEMKQ--I 477
                  5667899********************9998754..4 PP

  == domain 3  score: 4.7 bits;  conditional E-value: 0.004
  ANAPC4_WD40  37 edsevrsLaWkpdg.klLav..aysdgevrlldaesgkvvhslsvksekavtclgWge 91 
                  ++  ++++a+ p   +lLa   ++ d +v++++a +g ++ ++ ++++  vt l W++
   EEA20197.1 617 HSAAIKAVAFAPWQpTLLATggGITDCTVHFYHAPTGSCLAKIYMWAQ--VTGLVWSK 672
                  455566666655431455652257899******************999..9*999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (804 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       337  (0.0187964); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.30s 00:00:00.94 Elapsed: 00:00:00.46
# Mc/sec: 5237.69
//
Query:       EEA20198.1  [L=352]
Description: geranylgeranyl transferae type II alpha subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
      8e-35  117.6  17.4    3.6e-08   32.9   0.1    5.8  5  PPTA       Protein prenyltransferase alpha subunit repeat
  ------ inclusion threshold ------
      0.029   14.5   1.0      0.029   14.5   1.0    2.1  2  DUF1016_N  DUF1016 N-terminal domain
       0.04   14.4   0.2       0.11   13.0   0.0    1.8  2  PhoD_N     PhoD-like phosphatase, N-terminal domain
       0.51   10.2   2.1        3.1    7.6   0.4    2.1  2  VIT1       VIT family


Domain annotation for each model (and alignments):
>> PPTA  Protein prenyltransferase alpha subunit repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.4   4.6e-09   2.1e-05       5      25 ..      51      71 ..      51      74 .. 0.89
   2 !   29.6   2.2   8.8e-11   3.9e-07       2      27 ..      99     124 ..      98     125 .. 0.95
   3 !   25.8   0.0   1.4e-09   6.1e-06       1      27 [.     142     168 ..     142     169 .. 0.97
   4 !   32.9   0.1     8e-12   3.6e-08       3      27 ..     187     211 ..     186     212 .. 0.92
   5 !   12.4   0.3   2.3e-05       0.1       1      26 [.     231     255 ..     231     255 .. 0.85

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 4.6e-09
                HHHHHHH-TT-CHHHHHHHHH CS
        PPTA  5 tekliekdpkNYsaWnyRrwl 25
                +++l++k+p  Y++WnyRr +
  EEA20198.1 51 VSELLKKNPEYYTIWNYRRLI 71
                5799***************98 PP

  == domain 2  score: 29.6 bits;  conditional E-value: 8.8e-11
                 HHHHHHHHHH-TT-CHHHHHHHHHHC CS
        PPTA   2 LeltekliekdpkNYsaWnyRrwlle 27 
                 Le+   l++ +pk+Y++WnyR w+l 
  EEA20198.1  99 LEFLFPLLRSFPKCYWIWNYRLWILN 124
                 899999******************95 PP

  == domain 3  score: 25.8 bits;  conditional E-value: 1.4e-09
                 HHHHHHHHHHH-TT-CHHHHHHHHHHC CS
        PPTA   1 ELeltekliekdpkNYsaWnyRrwlle 27 
                 EL+l  k+++ d +N++ W yR +++e
  EEA20198.1 142 ELALLGKMLNADSRNFHGWGYRTFVIE 168
                 9************************98 PP

  == domain 4  score: 32.9 bits;  conditional E-value: 8e-12
                 HHHHHHHHH-TT-CHHHHHHHHHHC CS
        PPTA   3 eltekliekdpkNYsaWnyRrwlle 27 
                 ++t+k+i+++ +N+saW+yR   ++
  EEA20198.1 187 DYTTKMIKTNLSNFSAWHYRTKAIQ 211
                 8*******************98887 PP

  == domain 5  score: 12.4 bits;  conditional E-value: 2.3e-05
                 HHHHHHHHHHH-TT-CHHHHHHHHHH CS
        PPTA   1 ELeltekliekdpkNYsaWnyRrwll 26 
                 ELel  +++  dp ++s W+y++ l+
  EEA20198.1 231 ELELSHNAL-IDPYDQSLWFYHQNLM 255
                 788888888.56***********985 PP

>> DUF1016_N  DUF1016 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   1.0   6.4e-06     0.029       9      81 ..      11      83 ..       7     160 .. 0.84
   2 ?   -2.6   0.0       1.3   5.6e+03      98      98 ..     208     208 ..     180     246 .. 0.54

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 6.4e-06
   DUF1016_N  9 arqkaakavnselvelyweiGkrivekqeraeyGkkvikkLsedLkkefpevkGFsernlknmrqfyeaykee 81
                 + ++ ++ n++ v++y ++ + ++ek +  +y + +++++se Lkk+    + ++ r l +  +f+ea +e+
  EEA20198.1 11 VKAEVDTERNRKEVQTYRDLESSVHEKIAARKYSHDTLEQVSELLKKNPEYYTIWNYRRLIRQHEFAEATSES 83
                56778888899************************************99999999*******99999988533 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.3
   DUF1016_N  98 l 98 
                  
  EEA20198.1 208 K 208
                 2 PP

>> PhoD_N  PhoD-like phosphatase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0       2.4   1.1e+04      41      47 ..      22      28 ..       9      62 .. 0.50
   2 ?   13.0   0.0   2.5e-05      0.11      38      77 ..     168     208 ..     158     224 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 2.4
      PhoD_N 41 kkvvrkg 47
                k+v++ +
  EEA20198.1 22 KEVQTYR 28
                3333222 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 2.5e-05
      PhoD_N  38 eafkkvvrkgt.alatseldytvkvevtgLkpgqeyfYrfr 77 
                 ea+++++++g+  ++++++dyt k+  t+L+ ++ ++Yr +
  EEA20198.1 168 EALEDLADDGEpSMTQAQIDYTTKMIKTNLSNFSAWHYRTK 208
                 56677777777467889**********************88 PP

>> VIT1  VIT family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   0.4    0.0007       3.1      63     113 ..      13      61 ..       6     101 .. 0.76
   2 ?    2.2   0.1      0.03   1.4e+02      62     110 ..     185     234 ..     179     306 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0007
        VIT1  63 ekaerkreeeeleedpeegeaeelaeilearglseelaqevaaellknpda 113
                  + +++r+++e++++  + e   ++e ++ar+ s+++ ++v + l knp+ 
  EEA20198.1  13 AEVDTERNRKEVQTYR-DLE-SSVHEKIAARKYSHDTLEQVSELLKKNPEY 61 
                 4455667777777777.665.89*****************99999999886 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.03
        VIT1  62 lekaerkreeeeleedpe.egeaeelaeilearglseelaqevaaellkn 110
                 ++++++k+ + +l++ ++ +   + +++il +++ s+e+ ++v+++ l+ 
  EEA20198.1 185 QIDYTTKMIKTNLSNFSAwHYRTKAIQKILDEKKASDEERRQVLEQELEL 234
                 45566666677777777777788999999999999999999999988873 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (352 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       941  (0.0524848); expected 358.6 (0.02)
Passed bias filter:                      511  (0.0285013); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.38
# Mc/sec: 2773.76
//
Query:       EEA20199.1  [L=865]
Description: GTPase activating protein (Gyp5), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-49  168.8   5.7    1.8e-49  168.3   0.2    2.9  2  RabGAP-TBC     Rab-GTPase-TBC domain
  ------ inclusion threshold ------
       0.13   12.9  19.0          2    9.1   4.1    3.1  2  YabA           Initiation control protein YabA
        0.2   11.3  15.9        0.4   10.4  15.9    1.4  1  SHE3           SWI5-dependent HO expression protein 3
        2.2    8.6   4.6        1.1    9.6   0.4    2.7  2  HALZ           Homeobox associated leucine zipper
        3.4    7.7  24.1        7.1    6.7  23.1    2.0  2  UPF0242        Uncharacterised protein family (UPF0242) N-ter
        7.5    6.8  28.6       0.19   11.9   7.5    3.2  3  Cnn_1N         Centrosomin N-terminal motif 1
        9.5    6.3   8.5       0.38   10.8   0.7    2.1  2  Mago_nashi     Mago nashi protein


Domain annotation for each model (and alignments):
>> RabGAP-TBC  Rab-GTPase-TBC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  168.3   0.2   7.1e-53   1.8e-49      29     214 ..     456     641 ..     370     642 .. 0.84
   2 ?   -0.9   1.1       0.4     1e+03      14      68 ..     794     850 ..     779     854 .. 0.69

  Alignments for each domain:
  == domain 1  score: 168.3 bits;  conditional E-value: 7.1e-53
  RabGAP-TBC  29 eksekeksklekseeskelsqIkkDvprtfpesesfknkqgqnqLeriLkaysiynpevgYcqGmndivaplllvsldeeeaFwcfvsLlekyklrdly 127
                 e+  k+k k+ +++++k ++ I++D+    + s++f ++  q++L+ + kay++y+++vgY qG+n+i+ pll +++de eaF ++v+L++ky+lrd++
  EEA20199.1 456 ETARKKKLKEDTEAIRKLEKIIRRDLGSRTSYSKYFVSQGSQEALFGLCKAYALYDEAVGYAQGINFIAMPLL-FNMDEGEAFTLLVKLMNKYGLRDMF 553
                 4556778888999999**********9998989****************************************.999********************** PP

  RabGAP-TBC 128 tsslpglkrklkvleellkkkdpklykhlkeegldlelfaikwfltlflrefpletvlrlwDlll.egekfvllrvalailklleeel 214
                 ++++pgl+  l ++e+ll++  p+ly hl + g+ ++l+a++wfltlf++ fpl++vlr++Dl++ eg   ++lr+++ai++++ e l
  EEA20199.1 554 IQDMPGLHLHLFQFERLLEDLEPALYCHLRRRGVSPQLYATQWFLTLFAYRFPLQLVLRIYDLIFeEGLASTILRFGVAIMQRNVETL 641
                 **************************************************************6663777777*********9886665 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.4
  RabGAP-TBC  14 yep.evkrlkksekkqeksekeksklekseeskelsqIkkDvprtfpes..esfknkq 68 
                 ++p ev+++ + e+++  + +++ ++e+++ ++++   +kD+  t   +  e ++n++
  EEA20199.1 794 KQPaEVEEKLRTEMERIMKRNMEVQNENRNMEEQMAEMEKDLVETKM-KwaELSENHE 850
                 44466777777777788888888888888888889999999999966.2245555554 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   7.2     0.002       5.1       8      68 ..     741     801 ..     735     814 .. 0.76
   2 ?    9.1   4.1   0.00078         2       5      52 ..     816     863 ..     811     864 .. 0.90

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.002
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHXXXXXXXXXXXXXXXX CS
        YabA   8 dkleeleeqleelleeleelkeelaelleenaeLeleneklrerleeeekkekekkkelse 68 
                 +++++lee++e+  +e  +l +el+++  en+eL+  ne+lr +++e +   +++ +e++e
  EEA20199.1 741 ARIRSLEERTEKSDQEHVQLASELVRMKVENEELSDTNESLRVQVQELKIVVDKQPAEVEE 801
                 68999*************************************9996555444444333333 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.00078
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        YabA   5 elfdkleeleeqleelleeleelkeelaelleenaeLeleneklrerl 52 
                 e+ ++ +++eeq++e+ ++l e k+++ael e+++ L+     lr+ l
  EEA20199.1 816 EVQNENRNMEEQMAEMEKDLVETKMKWAELSENHEGLRQKWADLRRAL 863
                 66777899*******************************999999876 PP

>> SHE3  SWI5-dependent HO expression protein 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4  15.9   0.00016       0.4      63     191 ..     717     841 ..     692     862 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00016
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSXXXXXXXX CS
        SHE3  63 RKerrlkdlekelselkesveelklekkqlkkrlenssaseteleeelerlkvqYdalvdsqkeYkehYqqeieeLkesleklklenekqleelqeris 161
                  K r  k+ e+el+ lk+ v +++++   l++r+e+s ++  +l  el r+kv+ + l d+++  +     +++eLk  ++k   e e++l + +eri 
  EEA20199.1 717 EKVRTEKEREQELEGLKHTVASQAARIRSLEERTEKSDQEHVQLASELVRMKVENEELSDTNESLR----VQVQELKIVVDKQPAEVEEKLRTEMERIM 811
                 567777999***************************************************998876....6899************************* PP

                 XXX.XXXXXXXXXXXXXXXXXXXXXXXXXX CS
        SHE3 162 sndkdidtkldsynnkkknlesieeeknkk 191
                 + + +++++  +++++++++e+  +e + k
  EEA20199.1 812 KRNMEVQNENRNMEEQMAEMEKDLVETKMK 841
                 ****************99999865554444 PP

>> HALZ  Homeobox associated leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.4   0.00041       1.1      17      39 ..     767     789 ..     759     792 .. 0.93
   2 ?   -1.8   0.4       1.5   3.9e+03      16      39 ..     809     832 ..     801     835 .. 0.67

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00041
        HALZ  17 LksdydsLkkenekLkaelqeLk 39 
                 +k +++ L + ne+L+ ++qeLk
  EEA20199.1 767 MKVENEELSDTNESLRVQVQELK 789
                 7899******************8 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 1.5
        HALZ  16 aLksdydsLkkenekLkaelqeLk 39 
                     ++  +++en++ + +++e+ 
  EEA20199.1 809 RIMKRNMEVQNENRNMEEQMAEME 832
                 555566678899999888888765 PP

>> UPF0242  Uncharacterised protein family (UPF0242) N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7  23.1    0.0028       7.1      53     173 ..     711     832 ..     698     841 .. 0.78
   2 ?    0.9   5.8      0.17   4.2e+02      82     137 ..     801     860 ..     794     864 .. 0.46

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0028
     UPF0242  53 lllkwekalkekl.ekskleekeaklteldeglktkeealeelqeeeeeLkeeldakeeelerlkeenqqLqekleaiaedfeelkleleeqLaekqel 150
                   ++we++++++   +++le  ++ + ++   ++  ee  e++ +e+ +L+ el  ++ e e+l   n++L+++ ++ +  ++++  e+ee+L+ + e+
  EEA20199.1 711 YTTEWEEKVRTEKeREQELEGLKHTVASQAARIRSLEERTEKSDQEHVQLASELVRMKVENEELSDTNESLRVQVQELKIVVDKQPAEVEEKLRTEMER 809
                 4567888887766456778889999999999**********************************************9997777777777777777776 PP

     UPF0242 151 lqeyqetieeqrsvlekrqdqie 173
                 + + + ++++    +e++ ++ e
  EEA20199.1 810 IMKRNMEVQNENRNMEEQMAEME 832
                 66666666666666665554443 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.17
     UPF0242  82 eglktkeeal....eelqeeeeeLkeeldakeeelerlkeenqqLqekleaiaedfeelk 137
                 e+l+t+ e +     e+q+e+++++e+++++e+ l + k + ++L+e  e   +  ++l+
  EEA20199.1 801 EKLRTEMERImkrnMEVQNENRNMEEQMAEMEKDLVETKMKWAELSENHEGLRQKWADLR 860
                 333333332200002345555555555555665555555555555555555555555554 PP

>> Cnn_1N  Centrosomin N-terminal motif 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.5       4.1     1e+04      57      71 ..     461     475 ..     457     476 .. 0.60
   2 ?   11.9   7.5   7.5e-05      0.19       3      69 ..     723     788 ..     721     790 .. 0.88
   3 ?    5.3   7.1    0.0084        21      34      69 ..     803     838 ..     787     842 .. 0.80

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 4.1
      Cnn_1N  57 kelkekkkllreaek 71 
                 k+lke ++ +r++ek
  EEA20199.1 461 KKLKEDTEAIRKLEK 475
                 556666666666655 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 7.5e-05
      Cnn_1N   3 rEqeeqidkLkKENFdLKLriyfLeerleklseeqkeellkenielkveveslqkelkekkkllrea 69 
                 +E e++++ Lk    +   ri  Leer ek+++ ++ +l +e++ +kve+e+l +++++++ +++e+
  EEA20199.1 723 KEREQELEGLKHTVASQAARIRSLEERTEKSDQ-EHVQLASELVRMKVENEELSDTNESLRVQVQEL 788
                 7888888899999999999*************9.55678888*******************999986 PP

  == domain 3  score: 5.3 bits;  conditional E-value: 0.0084
      Cnn_1N  34 seeqkeellkenielkveveslqkelkekkkllrea 69 
                   +++e ++k n+e++ e+ +++ ++ e++k l e 
  EEA20199.1 803 LRTEMERIMKRNMEVQNENRNMEEQMAEMEKDLVET 838
                 236899*************************99876 PP

>> Mago_nashi  Mago nashi protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.7   0.00015      0.38      44     121 ..     686     764 ..     683     769 .. 0.87
   2 ?   -1.3   1.7      0.82   2.1e+03      52     100 ..     784     831 ..     769     856 .. 0.59

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00015
  Mago_nashi  44 kevlvskavlkelkriieeseilkeddakwpkkdkvgk.qeleiklgkehisfetakigslvdvqesedpeGlrvfyyl 121
                 ke++ +++++++   i  ++e+l++  ++w +k ++ k +e e++  k+ ++ ++a+i sl + +e++d e +++   l
  EEA20199.1 686 KEIYRADLMVQDACAIALTAEMLQSYTTEWEEKVRTEKeREQELEGLKHTVASQAARIRSLEERTEKSDQEHVQLASEL 764
                 78899999************************9986552688999999999******************9988766555 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.82
  Mago_nashi  52 vlkelkriieeseilkeddakwpkkdkvgkqeleiklgkehisfetaki 100
                  ++elk +++++  ++ +++   + +++ k+++e++ +++++  + a++
  EEA20199.1 784 QVQELKIVVDKQ-PAEVEEKLRTEMERIMKRNMEVQNENRNMEEQMAEM 831
                 455655444443.344445555666666777777776666665555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (865 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1831  (0.102125); expected 358.6 (0.02)
Passed bias filter:                      510  (0.0284455); expected 358.6 (0.02)
Passed Vit filter:                        87  (0.00485247); expected 17.9 (0.001)
Passed Fwd filter:                        35  (0.00195214); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.99u 0.31s 00:00:01.30 Elapsed: 00:00:00.52
# Mc/sec: 4997.05
//
Query:       EEA20200.1  [L=857]
Description: GTPase activating protein (Gyp5), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.8e-50  169.2   5.0    1.8e-49  168.3   0.2    2.9  2  RabGAP-TBC     Rab-GTPase-TBC domain
  ------ inclusion threshold ------
        0.3   11.2  20.1       0.84    9.7  20.1    1.7  1  UPF0242        Uncharacterised protein family (UPF0242) N-ter
        2.1    9.0  18.7        3.6    8.3   4.9    2.8  2  YabA           Initiation control protein YabA
        2.4    8.4   4.6          1    9.6   0.4    2.6  2  HALZ           Homeobox associated leucine zipper
        5.4    7.1   7.4       0.39   10.8   0.7    2.1  2  Mago_nashi     Mago nashi protein
          7    6.9  28.3       0.16   12.2   7.3    3.1  3  Cnn_1N         Centrosomin N-terminal motif 1


Domain annotation for each model (and alignments):
>> RabGAP-TBC  Rab-GTPase-TBC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  168.3   0.2     6e-53   1.8e-49      29     214 ..     456     641 ..     370     642 .. 0.84
   2 ?   -1.0   0.7      0.39   1.2e+03      15      59 ..     795     840 ..     779     854 .. 0.70

  Alignments for each domain:
  == domain 1  score: 168.3 bits;  conditional E-value: 6e-53
  RabGAP-TBC  29 eksekeksklekseeskelsqIkkDvprtfpesesfknkqgqnqLeriLkaysiynpevgYcqGmndivaplllvsldeeeaFwcfvsLlekyklrdly 127
                 e+  k+k k+ +++++k ++ I++D+    + s++f ++  q++L+ + kay++y+++vgY qG+n+i+ pll +++de eaF ++v+L++ky+lrd++
  EEA20200.1 456 ETARKKKLKEDTEAIRKLEKIIRRDLGSRTSYSKYFVSQGSQEALFGLCKAYALYDEAVGYAQGINFIAMPLL-FNMDEGEAFTLLVKLMNKYGLRDMF 553
                 4556778888999999**********9998989****************************************.999********************** PP

  RabGAP-TBC 128 tsslpglkrklkvleellkkkdpklykhlkeegldlelfaikwfltlflrefpletvlrlwDlll.egekfvllrvalailklleeel 214
                 ++++pgl+  l ++e+ll++  p+ly hl + g+ ++l+a++wfltlf++ fpl++vlr++Dl++ eg   ++lr+++ai++++ e l
  EEA20200.1 554 IQDMPGLHLHLFQFERLLEDLEPALYCHLRRRGVSPQLYATQWFLTLFAYRFPLQLVLRIYDLIFeEGLASTILRFGVAIMQRNVETL 641
                 **************************************************************6663777777*********9886665 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.39
  RabGAP-TBC  15 ep.evkrlkksekkqeksekeksklekseeskelsqIkkDvprtfp 59 
                 +p ev+++ + e+++  + +++ ++e+++ ++++   +kD+  t  
  EEA20200.1 795 QPaEVEEKLRTEMERIMKRNMEVQNENRNMEEQMAEMEKDLVETKM 840
                 4466677777777777778888888888888889999999988865 PP

>> UPF0242  Uncharacterised protein family (UPF0242) N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7  20.1   0.00028      0.84      53     173 ..     711     832 ..     698     841 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00028
     UPF0242  53 lllkwekalkekl.ekskleekeaklteldeglktkeealeelqeeeeeLkeeldakeeelerlkeenqqLqekleaiaedfeelkleleeqLaekqel 150
                   ++we++++++   +++le  ++ + ++   ++  ee  e++ +e+ +L+ el  ++ e e+l   n++L+++ ++ +  ++++  e+ee+L+ + e+
  EEA20200.1 711 YTTEWEEKVRTEKeREQELEGLKHTVASQAARIRSLEERTEKSDQEHVQLASELVRMKVENEELSDTNESLRVQVQELKIVVDKQPAEVEEKLRTEMER 809
                 4567888887766456778889999999999**********************************************9997777777777777777776 PP

     UPF0242 151 lqeyqetieeqrsvlekrqdqie 173
                 + + + ++++    +e++ ++ e
  EEA20200.1 810 IMKRNMEVQNENRNMEEQMAEME 832
                 66666666666666665554443 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   4.9    0.0012       3.6       8      58 ..     741     791 ..     736     802 .. 0.81
   2 ?    5.2   8.1     0.011        32      10      67 ..     785     843 ..     783     854 .. 0.77

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.0012
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHXXXXXX CS
        YabA   8 dkleeleeqleelleeleelkeelaelleenaeLeleneklrerleeeekk 58 
                 +++++lee++e+  +e  +l +el+++  en+eL+  ne+lr +++e +  
  EEA20200.1 741 ARIRSLEERTEKSDQEHVQLASELVRMKVENEELSDTNESLRVQVQELKIV 791
                 68999*************************************999654443 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.011
                 HHHHHHHHHHHHHHH.HHHHHHHHHHHHHHHHHHHHHHHHHHHHXXXXXXXXXXXXXXX CS
        YabA  10 leeleeqleelleel.eelkeelaelleenaeLeleneklrerleeeekkekekkkels 67 
                 ++el+  +++  +e+ e+l++e+++++++n e++ en+++ e+++e ek+  e+k +  
  EEA20200.1 785 VQELKIVVDKQPAEVeEKLRTEMERIMKRNMEVQNENRNMEEQMAEMEKDLVETKMKWA 843
                 566666666666666257**************************877777766666555 PP

>> HALZ  Homeobox associated leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.4   0.00035         1      17      39 ..     767     789 ..     759     792 .. 0.93
   2 ?   -1.8   0.4       1.3   3.9e+03      16      39 ..     809     832 ..     801     835 .. 0.67

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00035
        HALZ  17 LksdydsLkkenekLkaelqeLk 39 
                 +k +++ L + ne+L+ ++qeLk
  EEA20200.1 767 MKVENEELSDTNESLRVQVQELK 789
                 7899******************8 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 1.3
        HALZ  16 aLksdydsLkkenekLkaelqeLk 39 
                     ++  +++en++ + +++e+ 
  EEA20200.1 809 RIMKRNMEVQNENRNMEEQMAEME 832
                 555566678899999888888765 PP

>> Mago_nashi  Mago nashi protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.7   0.00013      0.39      44     121 ..     686     764 ..     683     770 .. 0.87
   2 ?   -1.0   1.1      0.58   1.7e+03      54      98 ..     786     829 ..     770     851 .. 0.56

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00013
  Mago_nashi  44 kevlvskavlkelkriieeseilkeddakwpkkdkvgk.qeleiklgkehisfetakigslvdvqesedpeGlrvfyyl 121
                 ke++ +++++++   i  ++e+l++  ++w +k ++ k +e e++  k+ ++ ++a+i sl + +e++d e +++   l
  EEA20200.1 686 KEIYRADLMVQDACAIALTAEMLQSYTTEWEEKVRTEKeREQELEGLKHTVASQAARIRSLEERTEKSDQEHVQLASEL 764
                 78899999************************9986552688999999999******************9988766555 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.58
  Mago_nashi  54 kelkriieeseilkeddakwpkkdkvgkqeleiklgkehisfeta 98 
                 +elk +++++  ++ +++   + +++ k+++e++ +++++  + a
  EEA20200.1 786 QELKIVVDKQ-PAEVEEKLRTEMERIMKRNMEVQNENRNMEEQMA 829
                 4444333333.3333444445555555555555555555444433 PP

>> Cnn_1N  Centrosomin N-terminal motif 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.5       3.4     1e+04      57      71 ..     461     475 ..     457     476 .. 0.60
   2 ?   12.2   7.3   5.3e-05      0.16       3      69 ..     723     788 ..     721     792 .. 0.89
   3 ?    4.9   9.4    0.0096        29      18      69 ..     780     838 ..     778     841 .. 0.78

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 3.4
      Cnn_1N  57 kelkekkkllreaek 71 
                 k+lke ++ +r++ek
  EEA20200.1 461 KKLKEDTEAIRKLEK 475
                 556666666666655 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 5.3e-05
      Cnn_1N   3 rEqeeqidkLkKENFdLKLriyfLeerleklseeqkeellkenielkveveslqkelkekkkllrea 69 
                 +E e++++ Lk    +   ri  Leer ek+++ ++ +l +e++ +kve+e+l +++++++ +++e+
  EEA20200.1 723 KEREQELEGLKHTVASQAARIRSLEERTEKSDQ-EHVQLASELVRMKVENEELSDTNESLRVQVQEL 788
                 7888888899999999999*************9.55678888*******************999987 PP

  == domain 3  score: 4.9 bits;  conditional E-value: 0.0096
      Cnn_1N  18 dLKLriyfLeerleklse.......eqkeellkenielkveveslqkelkekkkllrea 69 
                 +L+ ++++L+  ++k +        +++e ++k n+e++ e+ +++ ++ e++k l e 
  EEA20200.1 780 SLRVQVQELKIVVDKQPAeveeklrTEMERIMKRNMEVQNENRNMEEQMAEMEKDLVET 838
                 67777777777777777766667778999999999999999999999999999988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (857 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2291  (0.127782); expected 358.6 (0.02)
Passed bias filter:                      659  (0.0367561); expected 358.6 (0.02)
Passed Vit filter:                       100  (0.00557756); expected 17.9 (0.001)
Passed Fwd filter:                        30  (0.00167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.98u 0.33s 00:00:01.31 Elapsed: 00:00:00.51
# Mc/sec: 5093.75
//
Query:       EEA20201.1  [L=145]
Description: stress responsive A/B barrel domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    3.6e-11   43.5   0.0    4.5e-11   43.2   0.0    1.2  1  Dabb        Stress responsive A/B Barrel Domain
     0.0027   18.1   0.0     0.0041   17.5   0.0    1.4  1  Chalcone_N  Chalcone isomerase N-terminal domain


Domain annotation for each model (and alignments):
>> Dabb  Stress responsive A/B Barrel Domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.2   0.0     5e-15   4.5e-11       1      84 [.      44     129 ..      44     143 .. 0.89

  Alignments for each domain:
  == domain 1  score: 43.2 bits;  conditional E-value: 5e-15
                 EEEEEEEEESSTTTHHHHHHHHHHHHHH.....HHGSTTTSEEEEEEESSSSSTSTT-SEEEEEEESSHHHHHHHHT.SHHHHHHHHHHH CS
        Dabb   1 ikHivlfklkdevteeekaevlealeaL.....kdkipgiksievgrnvspeklakgydvvliseFeseedlkaYle.hpahvefvelvk 84 
                 +++i+lf + +e ++++    +e+++ L     kd+ p+i+ +++g   ++ + ++gy +++ ++F+++edlk Y++  pah+ f++++ 
  EEA20201.1  44 VERITLFNIPKEEHRAQL---VEEYKRLvktavKDGNPYITNVSFGPALPDPR-NRGYNFGVKMTFATLEDLKFYDAeCPAHQTFKAFLS 129
                 689*********999999...777777777789****************9998.**********************9678*****99876 PP

>> Chalcone_N  Chalcone isomerase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   0.0   4.6e-07    0.0041       9      63 ..      49     103 ..      38     130 .. 0.85

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 4.6e-07
  Chalcone_N   9 yvdvvkeeyrhklkewlyryhipdsiskfepyvtkyafynalpvppe.gerfgtvr 63 
                   ++ kee+r +l e  y+  ++ ++ + +py+t  +f  alp p + g +fg + 
  EEA20201.1  49 LFNIPKEEHRAQLVE-EYKRLVKTAVKDGNPYITNVSFGPALPDPRNrGYNFGVKM 103
                 567899*******88.59999************************64399999754 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (145 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       544  (0.0303419); expected 358.6 (0.02)
Passed bias filter:                      448  (0.0249875); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.40u 0.24s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1100.37
//
Query:       EEA20202.1  [L=164]
Description: sister chromatid cohesion protein Ctf8, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.8e-45  154.1   0.0    3.8e-45  153.7   0.0    1.2  1  Ctf8      Ctf8


Domain annotation for each model (and alignments):
>> Ctf8  Ctf8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  153.7   0.0   2.1e-49   3.8e-45       1     142 []      27     161 ..      27     161 .. 0.89

  Alignments for each domain:
  == domain 1  score: 153.7 bits;  conditional E-value: 2.1e-49
        Ctf8   1 llqtpsglalLElQGtinlpekekeeaeees....vsdeakaqetveevkiGrldfpdyspeae..dtkwmkrvyLyvgkhQrLtGevkkLakplavlr 93 
                 llqtpsgla+LElQGtin+p++++++++++     + + + a+++  e+++G+++fpdys+  +  +tkwmkrvyLy g++Qr+tGevkkLakplav++
  EEA20202.1  27 LLQTPSGLAILELQGTINFPATTDDDDDSDMntheEFQAEGAKTKIIETELGKIMFPDYSDLIDpeSTKWMKRVYLYAGRYQRMTGEVKKLAKPLAVIQ 125
                 79*******************999888877766544555666778899************998889********************************* PP

        Ctf8  94 rrksekkeeeeeeeekeeeksseeeseeeleivdivkykiifssrPePv 142
                 rr+++++e             + + +++eleiv+i+kykiif srPePv
  EEA20202.1 126 RRERSTTE-------------NGNGEQDELEIVEIIKYKIIFASRPEPV 161
                 **555544.............3678999********************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (164 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       510  (0.0284455); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.40
# Mc/sec: 1220.73
//
Query:       EEA20203.1  [L=264]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (264 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       415  (0.0231469); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.24s 00:00:00.65 Elapsed: 00:00:00.38
# Mc/sec: 2084.31
//
Query:       EEA20204.1  [L=199]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.9e-26   92.0   1.4    3.4e-26   91.2   1.4    1.4  1  Cnl2_NKP2  Cnl2/NKP2 family protein


Domain annotation for each model (and alignments):
>> Cnl2_NKP2  Cnl2/NKP2 family protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.2   1.4   1.9e-30   3.4e-26       1      65 []       5      69 ..       5      69 .. 0.98

  Alignments for each domain:
  == domain 1  score: 91.2 bits;  conditional E-value: 1.9e-30
   Cnl2_NKP2  1 esdILenfLlspasLptiisleqFkklFPrkkrssPqikrLYrdLqrqrsavldkVranIeeevk 65
                e++IL+nfLlspasLptiisl++F+++FP++++s+Pq+k LYr+Lq+ rs+++d +++nI +evk
  EEA20204.1  5 EESILSNFLLSPASLPTIISLQKFTEHFPKRLQSHPQVKVLYRELQELRSQDMDMITENILDEVK 69
                89************************************************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (199 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       932  (0.0519828); expected 358.6 (0.02)
Passed bias filter:                      586  (0.0326845); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.41
# Mc/sec: 1442.86
//
Query:       EEA20205.1  [L=330]
Description: histone acetylase complex subunit MRG15-2 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    8.6e-59  198.2   2.5    1.2e-58  197.7   2.5    1.2  1  MRG         MRG
      3e-10   39.8   2.7    6.4e-10   38.8   2.7    1.5  1  Tudor-knot  RNA binding activity-knot of a chromodomain
    0.00048   20.0   1.6     0.0014   18.4   1.6    1.8  1  Chromo      Chromo (CHRromatin Organisation MOdifier) domain
      0.008   16.6   0.1       0.02   15.3   0.1    1.6  1  PWWP        PWWP domain


Domain annotation for each model (and alignments):
>> MRG  MRG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  197.7   2.5   2.6e-62   1.2e-58       3     197 ..     124     304 ..     122     305 .. 0.94

  Alignments for each domain:
  == domain 1  score: 197.7 bits;  conditional E-value: 2.6e-62
         MRG   3 rkree...seeekkkrpeikvkleipeeLkklLedDwelitknkklvkLPaklnvkeILedYvkheakkkaetsereaeknvellkevvdgLriyFdft 98 
                 r r++   +e++++ rp+i+  + +p+ Lk+lL+dDwe++tkn+++v+LPa+++v+eIL+ Y ++e+ k++ t       + ++l+ev++g+++yFd+ 
  EEA20205.1 124 RGRDNeieKEDQFHLRPSIR--IMLPDTLKALLVDDWENVTKNQQVVALPAHHSVNEILQLYSDEEKPKRTTT------AELDVLEEVIMGIKEYFDKS 214
                 555555669***********..**********************************************99984......35799*************** PP

         MRG  99 lgkiLLYkfEraqykevlkkaeeekklelessseadqekepseiYGaeHLlRllvkLpellaktsmdekklklLlkhleeflefLaenheeyFseseYv 197
                 l+kiLLYkfEr+qy+ +++k+e+++        e+  +k p +iYGa+HL+Rl+  Lpel+a+t+md++++++L+++l++f+ +L++n+e++Fs ++Y+
  EEA20205.1 215 LDKILLYKFEREQYRLLRQKWESGA--------ENYTDKGPLDIYGAHHLARLFAVLPELIAQTNMDQQSINRLREELSKFTIWLSRNSEKFFS-NKYI 304
                 *********************9987........36788*******************************************************9.9997 PP

>> Tudor-knot  RNA binding activity-knot of a chromodomain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.8   2.7   1.4e-13   6.4e-10       5      54 ..      12      65 ..       9      66 .. 0.93

  Alignments for each domain:
  == domain 1  score: 38.8 bits;  conditional E-value: 1.4e-13
                TEEEEEETTSCEEEEEEEEEEE.....TSSCEEEEEEETTS-CCC-EEEETTTEE CS
  Tudor-knot  5 ckvlvrkkdgelrkAeilsire.....kkgkyeYYVHYeefNkRlDeWVsaerid 54
                +kvl+++ ++ l++A+i + +      +k++yeY VHY ++   +D WV++er++
  EEA20205.1 12 EKVLCFH-HEVLYEAKIMDMKHvdpddRKSPYEYLVHYKGWKNTWDDWVPQERLR 65
                79*****.*************9998877788**********************97 PP

>> Chromo  Chromo (CHRromatin Organisation MOdifier) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   1.6   3.2e-07    0.0014       5      43 ..      26      67 ..      25      73 .. 0.83

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 3.2e-07
                EEEEEE.EETTEEC..EEEEEEETTSTGGGTEEEEGGGCSSH CS
      Chromo  5 rIidhr.tdkdgle..leYlVKWkglpysentWEpeenlekc 43
                +I+d++ +d d ++  +eYlV++kg+    + W p+e l k 
  EEA20205.1 26 KIMDMKhVDPDDRKspYEYLVHYKGWKNTWDDWVPQERLRKF 67
                7999996555555589*********************99987 PP

>> PWWP  PWWP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.1   4.5e-06      0.02      19      69 ..      25      73 ..      19      92 .. 0.80

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 4.5e-06
                EEEEECCCCCCCCHCT---SSSEEEEEETTTTEE..EEE-GGGEEE-SHHHHH CS
        PWWP 19 avvidpeevpekvlkkkekskelylVkFfgdkey..awvkekdlkpfteedee 69
                a ++d ++v  +++k++ +    ylV++ g k++   wv++++l++ftee+ e
  EEA20205.1 25 AKIMDMKHVDPDDRKSPYE----YLVHYKGWKNTwdDWVPQERLRKFTEENRE 73
                6788888888888776655....*******999999************98854 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (330 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       914  (0.0509789); expected 358.6 (0.02)
Passed bias filter:                      591  (0.0329634); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2236.80
//
Query:       EEA20206.1  [L=245]
Description: histone acetylase complex subunit MRG15-2 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      4e-59  199.3   2.5    4.9e-59  199.0   2.5    1.0  1  MRG       MRG


Domain annotation for each model (and alignments):
>> MRG  MRG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  199.0   2.5   2.7e-63   4.9e-59       3     197 ..      39     219 ..      37     220 .. 0.94

  Alignments for each domain:
  == domain 1  score: 199.0 bits;  conditional E-value: 2.7e-63
         MRG   3 rkree...seeekkkrpeikvkleipeeLkklLedDwelitknkklvkLPaklnvkeILedYvkheakkkaetsereaeknvellkevvdgLriyFdft 98 
                 r r++   +e++++ rp+i+  + +p+ Lk+lL+dDwe++tkn+++v+LPa+++v+eIL+ Y ++e+ k++ t       + ++l+ev++g+++yFd+ 
  EEA20206.1  39 RGRDNeieKEDQFHLRPSIR--IMLPDTLKALLVDDWENVTKNQQVVALPAHHSVNEILQLYSDEEKPKRTTT------AELDVLEEVIMGIKEYFDKS 129
                 555555669***********..**********************************************99984......35799*************** PP

         MRG  99 lgkiLLYkfEraqykevlkkaeeekklelessseadqekepseiYGaeHLlRllvkLpellaktsmdekklklLlkhleeflefLaenheeyFseseYv 197
                 l+kiLLYkfEr+qy+ +++k+e+++        e+  +k p +iYGa+HL+Rl+  Lpel+a+t+md++++++L+++l++f+ +L++n+e++Fs ++Y+
  EEA20206.1 130 LDKILLYKFEREQYRLLRQKWESGA--------ENYTDKGPLDIYGAHHLARLFAVLPELIAQTNMDQQSINRLREELSKFTIWLSRNSEKFFS-NKYI 219
                 *********************9987........36788*******************************************************9.9997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (245 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       721  (0.0402142); expected 358.6 (0.02)
Passed bias filter:                      498  (0.0277762); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.24s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 1694.47
//
Query:       EEA20207.1  [L=651]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-89  299.6   0.1    2.7e-89  298.8   0.1    1.4  1  DUF1741   Domain of unknown function (DUF1741)


Domain annotation for each model (and alignments):
>> DUF1741  Domain of unknown function (DUF1741)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  298.8   0.1   1.5e-93   2.7e-89       1     233 []     406     648 ..     406     648 .. 0.93

  Alignments for each domain:
  == domain 1  score: 298.8 bits;  conditional E-value: 1.5e-93
     DUF1741   1 rvlaavilDllvdfinhnLrkrldvelytlalgillrllsylkrskvRLayhWselwraLlslvrflttyasdlkskpqidtlldslvnllalfisaGd 99 
                 rvla+vi+D+++d+i+hnLr+rld++ly+ +++il rl++yl+++k+RL+yhW+e+wr+Llsl+rflttyasdl+s p+idtl++sl++l+a+++s+Gd
  EEA20207.1 406 RVLATVIFDMMIDTITHNLRRRLDTNLYSYTIAILIRLFTYLSSNKTRLTYHWAEMWRTLLSLMRFLTTYASDLSSAPHIDTLTTSLIDLIAFTLSTGD 504
                 79************************************************************************************************* PP

     DUF1741 100 tfLpdpasYddLfYklvetgevltkfrdlyklalrasvtteseakesakkatnsidnlisvsthfkell........eekkakk..........kkkel 180
                 +fLpdpasYddLfYk+ve+g+++++frd+y+l++   +++ ++++ +++++ +si++l++vsthf +ll        e     +          +k++l
  EEA20207.1 505 AFLPDPASYDDLFYKIVEAGPIIARFRDVYNLSTG--TNAPATSSLQSHQHGASINTLLTVSTHFLSLLfqtdkptaE-----AgeraqaattaRKRNL 596
                 *********************************53..45666678889999******************766555441.....15556667777***** PP

     DUF1741 181 tpeqvlevIkqgYetLslkalqegLdkwekyreedektflkkivrvavedark 233
                  p++v+++Ik+gY+tLs+++ qegL++wek+re+d +  lkk++r+avedar+
  EEA20207.1 597 GPREVHQIIKKGYDTLSIQP-QEGLSTWEKWREADRRLYLKKAARCAVEDARR 648
                 *******************8.*****************************995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (651 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       560  (0.0312343); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.27s 00:00:00.92 Elapsed: 00:00:00.44
# Mc/sec: 4450.03
//
Query:       EEA20208.1  [L=240]
Description: iron-sulfur cluster assembly accessory protein Isa1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    5.9e-21   74.7   0.0    9.7e-21   74.1   0.0    1.4  1  Fe-S_biosyn  Iron-sulphur cluster biosynthesis


Domain annotation for each model (and alignments):
>> Fe-S_biosyn  Iron-sulphur cluster biosynthesis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.1   0.0   5.4e-25   9.7e-21       3     111 .]     137     236 ..     135     236 .. 0.96

  Alignments for each domain:
  == domain 1  score: 74.1 bits;  conditional E-value: 5.4e-25
                  EEE-HHHHHHHHHHHHCTTEC.EEEEEECCTSCCGGS.TT.EEEEEEEEESSTSTTTEEEEEETTEEEEEEGGGHHHS.TTEEEEEEEETTEEEEEEE CS
  Fe-S_biosyn   3 itlteaAaeklkkllaedkke.lrLdvddgggpyskggCsiggkyslvlvdeedeeydevlesnggkvyvksyslvfldeglvldfvedlgtlgLksd 99 
                  +tlt++A+ +l+++l++ + + +r++v++ g       Cs g  ysl++vd++  ++dev+e++g+kv+++s++l  +  g ++d++ed+ + ++ + 
   EEA20208.1 137 MTLTPTAVSQLQSMLSQPDPKmIRVGVKNRG-------CS-GLAYSLEYVDKP-GKFDEVVEQDGVKVLIDSKALFSI-IGSEMDWHEDKLSQRFVFR 224
                  79***************55555*********.......**.************.************************.9****************** PP

                  TCCEEEEEEEEE CS
  Fe-S_biosyn 100 ngilddnvglgk 111
                  n+++++++g+g+
   EEA20208.1 225 NPNIKEQCGCGE 236
                  **********85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (240 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       526  (0.0293379); expected 358.6 (0.02)
Passed bias filter:                      375  (0.0209158); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 1594.46
//
Query:       EEA20209.1  [L=330]
Description: conserved membrane protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.8e-42  144.8   0.1    1.8e-42  144.8   0.1    1.6  2  DUF2407_C    DUF2407 C-terminal domain
    1.8e-35  121.6   0.6    2.8e-35  121.0   0.0    1.6  2  DUF2407      DUF2407 ubiquitin-like domain
    1.8e-05   24.4   0.0    3.6e-05   23.4   0.0    1.5  1  ubiquitin    Ubiquitin family
  ------ inclusion threshold ------
      0.013   15.6   0.0      0.026   14.6   0.0    1.5  1  Rad60-SLD_2  Ubiquitin-2 like Rad60 SUMO-like


Domain annotation for each model (and alignments):
>> DUF2407_C  DUF2407 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.1       2.5   1.1e+04      35      37 ..     162     164 ..     146     180 .. 0.40
   2 !  144.8   0.1     4e-46   1.8e-42       1     140 []     188     327 ..     188     327 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 2.5
   DUF2407_C  35 tmp 37 
                 +++
  EEA20209.1 162 STS 164
                 111 PP

  == domain 2  score: 144.8 bits;  conditional E-value: 4e-46
   DUF2407_C   1 iGFDRLlsaGfseeeieaLRsqFrsiygseetpdtmpsdleeeeeeelreLEerWidstanaeeaae....aeeegeaakeee.....nsvdseeskan 90 
                 +GFDRLlsaGf+++e++aLRsqF ++++ ++tpd+mp+       +elreLE+rW+d++++a+ a      a + g+++   +         s++++a+
  EEA20209.1 188 RGFDRLLSAGFTPSEVAALRSQFMALQSINHTPDAMPTG------DELRELEDRWMDEGSSADGAGVgltfAGGGGGGT---GgdeggGGFGSSSNSAL 277
                 7**************************************......9**************8888777654322222222...23457755679999*** PP

   DUF2407_C  91 edlliGlliGfflglfalllllkeegllnkrqkmaviaGvlvnlvlglvr 140
                 +d+l+G+++Gff++++++++l +eeg++++r+ +av++Gv++nlv g+vr
  EEA20209.1 278 DDMLWGAVMGFFWPIGCAMWLRREEGVWSWRKGLAVFVGVVINLVSGAVR 327
                 *********************************************99998 PP

>> DUF2407  DUF2407 ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.0   0.0   6.3e-39   2.8e-35       2     104 .]      21     135 ..      20     135 .. 0.93
   2 ?   -2.6   0.2       1.9   8.5e+03      62      84 ..     149     171 ..     141     182 .. 0.47

  Alignments for each domain:
  == domain 1  score: 121.0 bits;  conditional E-value: 6.3e-39
     DUF2407   2 llviRFsasipDleLdipdpntttvagLkqliRerlpaelasrrLrLIyaGrlLedttslasslklpees.........vsdkaekskekgkapvr... 88 
                 +l+iRFsasipD++Ldip+p+tttvagLkqliR +lp++la+rr+rLIy+Gr Led++sl+++lklp+++         ++  ++++++kgka+vr   
  EEA20209.1  21 HLTIRFSASIPDVQLDIPSPSTTTVAGLKQLIRAHLPSDLANRRIRLIYSGRGLEDASSLRTALKLPSRTstpssttdvEDGLSSSKDKKGKAVVRdam 119
                 79*****************************************************************8889*****99655666777889999999888 PP

     DUF2407  89 eqeeeriYihCsiGde 104
                 +++ +r+Y+hCsiGd+
  EEA20209.1 120 PSDVPRVYVHCSIGDI 135
                 8999**********96 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.9
     DUF2407  62 asslklpeesvsdkaekskekgk 84 
                 as   +++++++d +++   k++
  EEA20209.1 149 ASTFLVQQQQQQDSTSSLTVKER 171
                 44444444433333333333333 PP

>> ubiquitin  Ubiquitin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.4   0.0   8.1e-09   3.6e-05       9      55 ..      33      81 ..      22      86 .. 0.85

  Alignments for each domain:
  == domain 1  score: 23.4 bits;  conditional E-value: 8.1e-09
                EEEEEEEETTSBHHHHHHHHHHHH..TSSGGGEEEEETTEEE-TTSBHG CS
   ubiquitin  9 kkitleveesdtveelKekiaeke..gipaeqqrLiysGkvLedertle 55
                 ++++  ++++tv+ lK+ i ++   +++ +++rLiysG+ Led ++l+
  EEA20209.1 33 VQLDIPSPSTTTVAGLKQLIRAHLpsDLANRRIRLIYSGRGLEDASSLR 81
                567788899*************99545*****************99987 PP

>> Rad60-SLD_2  Ubiquitin-2 like Rad60 SUMO-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.0   5.7e-06     0.026      21      69 ..      40      83 ..      21     113 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 5.7e-06
                 ETT-BHHHHHHHHHHHS-TT-SSS--SCCCEEEEETTEEE-TTSBCCCC CS
  Rad60-SLD_2 21 sdaatvaelkekviaqWPkdkeekpksvndlklilaGkiLennktlkel 69
                 ++++tva lk+ + a+ P d  +       ++li++G+ Le++  l  +
   EEA20209.1 40 PSTTTVAGLKQLIRAHLPSDLAN-----RRIRLIYSGRGLEDASSLRTA 83
                 5699****************999.....89*************999765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (330 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       802  (0.044732); expected 358.6 (0.02)
Passed bias filter:                      587  (0.0327403); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.50u 0.24s 00:00:00.74 Elapsed: 00:00:00.41
# Mc/sec: 2404.28
//
Query:       EEA20210.1  [L=226]
Description: vesicle transport v-snare protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.7e-22   78.9   5.5    2.7e-22   78.9   5.5    2.0  3  V-SNARE        Vesicle transport v-SNARE protein N-terminus
    4.3e-18   65.3   6.1    4.3e-18   65.3   6.1    2.6  2  V-SNARE_C      Snare region anchored in the vesicle membrane 
    0.00058   19.7   0.3    0.00058   19.7   0.3    2.2  3  Sec20          Sec20
     0.0017   18.2   0.0     0.0035   17.2   0.0    1.5  1  Thump_like     THUMP domain-like
     0.0044   15.1   2.1       0.31    8.9   0.2    2.1  2  Prominin       Prominin
  ------ inclusion threshold ------
      0.018   14.4  11.0      0.032   13.6  11.0    1.4  1  DUF4407        Domain of unknown function (DUF4407)
      0.019   13.3   1.2      0.047   12.0   0.1    2.0  2  Fusion_gly     Fusion glycoprotein F0
      0.047   14.1   0.4        3.6    8.1   0.0    2.6  2  LPP            Lipoprotein leucine-zipper
       0.89    9.1  14.4         12    5.4  14.5    2.0  1  Exonuc_VII_L   Exonuclease VII, large subunit
        1.3    8.9   7.9       0.22   11.3   1.8    2.7  3  Synaptobrevin  Synaptobrevin
        3.6    7.9  11.6       0.43   10.9   0.2    3.3  3  YqjK           YqjK-like protein
        4.3    7.4   8.5         17    5.4   0.0    3.0  3  DUF4083        Domain of unknown function (DUF4083)
          5    6.4   5.5       0.88    8.9   1.1    1.8  2  FAM76          FAM76 protein
        7.8    6.7   8.7         81    3.4   8.7    2.3  1  zf-C4H2        Zinc finger-containing protein


Domain annotation for each model (and alignments):
>> V-SNARE  Vesicle transport v-SNARE protein N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.9   5.5   2.1e-25   2.7e-22       2      78 ..      22      98 ..      21      99 .. 0.97
   2 ?   -2.4   0.1       5.1   6.5e+03      15      15 ..     136     136 ..     122     156 .. 0.48
   3 ?   -2.5   0.0       5.5     7e+03      23      35 ..     167     179 ..     159     195 .. 0.53

  Alignments for each domain:
  == domain 1  score: 78.9 bits;  conditional E-value: 2.1e-25
     V-SNARE  2 kellaeiksklarlsslageerkaalreiekkldeaeelldqMelEvrnlpsserasykaklreykselkklkkelk 78
                k ++a++++kl+++++ +ge+rk+a+ ++e++ldea elldqM +E +n+ps++r++++ ++r+y s++++lk++lk
  EEA20210.1 22 KLVQADLNQKLDQIAETTGEQRKSAIGQAERALDEATELLDQMRMEKQNIPSAARSKVNVRFRNYSSDIDELKRKLK 98
                6789***********************************************************************98 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 5.1
     V-SNARE  15 l 15 
                 l
  EEA20210.1 136 L 136
                 1 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 5.5
     V-SNARE  23 rkaalreiekkld 35 
                 +++++ +  + l 
  EEA20210.1 167 QRETIERTRQNLH 179
                 3333333333333 PP

>> V-SNARE_C  Snare region anchored in the vesicle membrane C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.1      0.89   1.1e+03      14      31 ..      51      64 ..      39     101 .. 0.58
   2 !   65.3   6.1   3.4e-21   4.3e-18       1      66 []     134     199 ..     134     199 .. 0.99

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.89
   V-SNARE_C 14 hrivdetisiGaailedL 31
                +r +      +++ l+++
  EEA20210.1 51 ERAL----DEATELLDQM 64
                3333....3333333333 PP

  == domain 2  score: 65.3 bits;  conditional E-value: 3.4e-21
   V-SNARE_C   1 erllresdrlknShrivdetisiGaailedLhsQretLkrarsklhnvanrlgksnsiLrsikrRv 66 
                 erl+r+s rl++S+r++ et+ iG  +l dLh+Qret++r+r+ lh+   ++++s ++Lr + rR+
  EEA20210.1 134 ERLERSSARLQESQRLALETEDIGRGTLADLHQQRETIERTRQNLHQSEGYVDTSIKTLRGMARRM 199
                 79***************************************************************7 PP

>> Sec20  Sec20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1       1.8   2.3e+03      41      41 ..      53      53 ..      20      88 .. 0.56
   2 ?   -2.3   0.0       3.3   4.2e+03      23      47 ..      76      99 ..      55     103 .. 0.51
   3 !   19.7   0.3   4.5e-07   0.00058       9      86 ..     142     222 ..     133     226 .] 0.84

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 1.8
       Sec20 41 l 41
                +
  EEA20210.1 53 A 53
                1 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 3.3
       Sec20 23 qSeenleeldastkslekleeeykq 47
                +S+ n+  +++ + ++ +l+ ++k+
  EEA20210.1 76 RSKVNV-RFRNYSSDIDELKRKLKS 99
                344443.355555555555555555 PP

  == domain 3  score: 19.7 bits;  conditional E-value: 4.5e-07
       Sec20   9 slraisqllsqevqqSeenleeldastkslekleeeykqvedvlsrskklvkklerrdktdkll...vflalglflacvvy 86 
                  l+++++l  ++ +    +l +l+++ +++e++ ++++q e+ + +s k ++ + rr  t++++   ++  l l++++v+y
  EEA20210.1 142 RLQESQRLALETEDIGRGTLADLHQQRETIERTRQNLHQSEGYVDTSIKTLRGMARRMATNRIItiaIITVLILLIFAVIY 222
                 5677777777777778889******************************************98633367778888888888 PP

>> Thump_like  THUMP domain-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   2.8e-06    0.0035       6      59 ..      60     108 ..      57     118 .. 0.81

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 2.8e-06
  Thump_like   6 vlevlpfskkklkkllrergigkanikkRgfpldpeeLrkklklkdggraatLv 59 
                  l+++ + k+++ ++ r+    k+n+  R++  d +eL++klk   +++++ L+
  EEA20210.1  60 LLDQMRMEKQNIPSAARS----KVNVRFRNYSSDIDELKRKLKSL-SDDRRALF 108
                 567888888999999866....9********************86.34355555 PP

>> Prominin  Prominin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.9   0.2   0.00025      0.31     335     417 ..      21     106 ..       8     109 .. 0.73
   2 !    6.1   0.1    0.0018       2.3     376     434 ..     162     222 ..     122     225 .. 0.67

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00025
    Prominin 335 lssivkeglarlneipekvknqtaevvpdlkkalakgre...qikklakkiprealdavisdlenterssktfddvvekyekyrwl 417
                 l+ +  + +++l++i e+  +q ++ + +  +al++++e   q+++++++ip+ a ++v     n  +++++ +++++ ++ +r++
  EEA20210.1  21 LKLVQADLNQKLDQIAETTGEQRKSAIGQAERALDEATElldQMRMEKQNIPSAARSKVNVRFRNYSSDIDELKRKLKSLSDDRRA 106
                 55555556778888888888888888888888888887622245556788888888888888888888888888888888888775 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.0018
    Prominin 376 kklakkiprealdavisdlente....rssktfddvvekyekyrwliglivcsllllivvili 434
                  +l ++  re+++++ ++l+++e    +s+kt      ++ ++r +   i+ +l+lli  + +
  EEA20210.1 162 ADLHQQ--RETIERTRQNLHQSEgyvdTSIKTLRGMARRMATNRIITIAIITVLILLIFAVIY 222
                 333332..4777777777776651111455556666677778888888888888888877665 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6  11.0   2.5e-05     0.032     100     274 ..      20     221 ..      11     224 .. 0.67

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 2.5e-05
     DUF4407 100 eLkiFekeIdaelaeeqqeeakelkeqlaaa..............ltaelaeleaqia...........alqaeidaaearldalraeaqkeldgtk.. 171
                 eLk+ + +++++l+++++ + ++ k+ + +a                                      + +  +++ ++++d+l++++++  d  +  
  EEA20210.1  20 ELKLVQADLNQKLDQIAETTGEQRKSAIGQAeraldeatelldqmR-----------MekqnipsaarsKVNVRFRNYSSDIDELKRKLKSLSDDRRal 107
                 5566666667777766666666666665555554444333222221...........122233343333333333333333444443333333333366 PP

     DUF4407 172 .gtgttgvaGkgpaakekkaqldaaqaelaelkakld...............atarlaalraelaeleaerakeraasqaaaaaddGllarlealdrlt 254
                  g++ t ++  g++  e ++ql   +++l+  +a+l+                 a+l ++r+++++ ++++++++   +++++  +G++ r+ a +r++
  EEA20210.1 108 fGDRYTDDPEAGDVHMEQRQQLLSGTERLERSSARLQesqrlaletedigrgTLADLHQQRETIERTRQNLHQSEGYVDTSIKTLRGMARRM-ATNRII 205
                 6777777888889999988888888888888888888999************99*********************************98887.556665 PP

     DUF4407 255 kedatallarlllfllflai 274
                     t++++ +l++l f +i
  EEA20210.1 206 ----TIAIITVLILLIFAVI 221
                 ....6888888888888776 PP

>> Fusion_gly  Fusion glycoprotein F0
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.1      0.17   2.2e+02     442     464 ..      44      66 ..      15      75 .. 0.54
   2 ?   12.0   0.1   3.6e-05     0.047     437     484 ..     170     217 ..     127     221 .. 0.81

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.17
                 HHHHHHHHHHHHHHCCCCTCCCH CS
  Fusion_gly 442 nesleqskdlleesnkiLdsvnk 464
                 ++ + q+   l+e+ ++Ld++  
  EEA20210.1  44 KSAIGQAERALDEATELLDQMRM 66 
                 33455666666666666666554 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 3.6e-05
                 HHHHHHHHHHHHHHHHHHHCCCCTCCCHHHHHTTXXXXXXXXXXXXXX CS
  Fusion_gly 437 elskvnesleqskdlleesnkiLdsvnkkllstaivivlivlvivvll 484
                  +++  ++l+qs  +++ s k L+++ + +++  i+ ++i+ v++ l+
  EEA20210.1 170 TIERTRQNLHQSEGYVDTSIKTLRGMARRMATNRIITIAIITVLILLI 217
                 56778899******************8777766665555555555544 PP

>> LPP  Lipoprotein leucine-zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.5     0.088   1.1e+02      11      33 ..      27      53 ..      23      59 .. 0.61
   2 ?    8.1   0.0    0.0028       3.6       5      25 ..      86     106 ..      82     118 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.088
         LPP 11 qLkskvdqlssd....vnsakaaaqaa 33
                +L++k dq+++      +sa  +a+ a
  EEA20210.1 27 DLNQKLDQIAETtgeqRKSAIGQAERA 53
                699999999998433323333334444 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0028
         LPP   5 LssqVsqLkskvdqlssdvns 25 
                  ss++ +Lk+k ++ls+d  +
  EEA20210.1  86 YSSDIDELKRKLKSLSDDRRA 106
                 59**************99655 PP

>> Exonuc_VII_L  Exonuclease VII, large subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4  14.5    0.0093        12     142     256 ..      18     178 ..       7     208 .. 0.56

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.0093
  Exonuc_VII_L 142 kaeleeqleelerrlekaikrlleekkqrleklasrlkspeellerkrqrldeleerleralkkqlkkkrerleelkerlk................ 222
                   +ael+   ++l+++l++ ++++ e++k+ + +++++l +++ell++ r + +++ +  +++++ ++++ +++++elk++lk                
    EEA20210.1  18 EAELKLVQADLNQKLDQIAETTGEQRKSAIGQAERALDEATELLDQMRMEKQNIPSAARSKVNVRFRNYSSDIDELKRKLKslsddrralfgdrytd 114
                   4555555566666666666667777777788888888777778877777777777777777777777777777777777742444444444444444 PP

  Exonuc_VII_L 223 ............ekleekk.....erlkklkerle..................lleekkerleeleekl 256
                               +     +     erl++ ++rl+                   l++++e++e+  ++l
    EEA20210.1 115 dpeagdvhmeqrQ-----QllsgtERLERSSARLQesqrlaletedigrgtlaDLHQQRETIERTRQNL 178
                   4444333222221.....022222333333333333333334444444443333444444444444444 PP

>> Synaptobrevin  Synaptobrevin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.2         1   1.3e+03      10      32 ..      30      52 ..      24      76 .. 0.54
   2 ?   -1.0   0.0       1.2   1.6e+03      42      59 ..     128     145 ..     122     153 .. 0.55
   3 ?   11.3   1.8   0.00017      0.22      38      88 ..     172     222 ..     139     223 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 1
                   HHHHCCCCHHCCHHHHCHCCCCC CS
  Synaptobrevin 10 aevdevkdimkeNidkvlergek 32
                   +++d++ +++ e  ++++   e+
     EEA20210.1 30 QKLDQIAETTGEQRKSAIGQAER 52
                   44444444444444444433333 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 1.2
                    HHHHHHHHHHHHHHHHHH CS
  Synaptobrevin  42 nLqssaqqFkkqarklkr 59 
                    +L s ++  ++++ +l++
     EEA20210.1 128 QLLSGTERLERSSARLQE 145
                    444444444444444443 PP

  == domain 3  score: 11.3 bits;  conditional E-value: 0.00017
                    CCCHHHHHHHHHHHHHHHHHHHHHHHHTXXXXXXXXXXXXXXXXXXXXXXX CS
  Synaptobrevin  38 dktenLqssaqqFkkqarklkrkmwwknmkliiililvvlililiiiivic 88 
                    ++t +   +++ +  ++ k  r m  +    +ii i+++++lil+i++vi+
     EEA20210.1 172 ERTRQNLHQSEGYVDTSIKTLRGMARRMATNRIITIAIITVLILLIFAVIY 222
                    56677778999********99999999999999999999999999998875 PP

>> YqjK  YqjK-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.2      0.69   8.8e+02       8      29 ..      42      64 ..      33      67 .. 0.77
   2 ?    1.8   1.5      0.23   2.9e+02       7      26 ..     124     143 ..     123     149 .. 0.87
   3 ?   10.9   0.2   0.00033      0.43       5      40 ..     164     199 ..     161     216 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.69
        YqjK  8 QRl.dLaqaaepwekalapvDrg 29
                QR+ ++ qa + + +a++ +D+ 
  EEA20210.1 42 QRKsAIGQAERALDEATELLDQM 64
                55426888888899999999986 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.23
        YqjK   7 qQRldLaqaaepwekalapv 26 
                 +QR++L   +e++e+  a++
  EEA20210.1 124 EQRQQLLSGTERLERSSARL 143
                 6*************998876 PP

  == domain 3  score: 10.9 bits;  conditional E-value: 0.00033
        YqjK   5 ieqQRldLaqaaepwekalapvDrgwqtlrslrkhl 40 
                  +qQR+ +++  +++++    vD++++tlr + + +
  EEA20210.1 164 LHQQRETIERTRQNLHQSEGYVDTSIKTLRGMARRM 199
                 68****************************776554 PP

>> DUF4083  Domain of unknown function (DUF4083)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   0.0     0.013        17      40      51 ..      25      36 ..      15      38 .. 0.84
   2 ?   -2.0   0.0       2.9   3.7e+03      44      55 ..      51      62 ..      43      63 .. 0.80
   3 ?    2.5   4.2      0.11   1.5e+02       6      23 ..     204     221 ..     201     224 .. 0.84

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.013
     DUF4083 40 skeleqKLDkiI 51
                +  l+qKLD+i 
  EEA20210.1 25 QADLNQKLDQIA 36
                678*******96 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 2.9
     DUF4083 44 eqKLDkiIeLLe 55
                e+ LD+  eLL+
  EEA20210.1 51 ERALDEATELLD 62
                7789**999996 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.11
     DUF4083   6 iyliivivLilllvfsft 23 
                 i++i++i +++ll+f+++
  EEA20210.1 204 IITIAIITVLILLIFAVI 221
                 899999999999999887 PP

>> FAM76  FAM76 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   1.1   0.00068      0.88     219     291 ..      30     103 ..       7     110 .. 0.81
   2 ?   -0.7   0.2      0.56   7.2e+02     212     238 ..     155     181 ..     114     203 .. 0.49

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00068
       FAM76 219 vavtqLkeei.aslkkqleqkdqellekdkkitelkaellekekelreklkelekeakekieklekkirellke 291
                  ++ q+ e+  +++k  + q + +l e    + +++ e+++  +  r+k++ + +++++ i++l++k ++l  +
  EEA20210.1  30 QKLDQIAETTgEQRKSAIGQAERALDEATELLDQMRMEKQNIPSAARSKVNVRFRNYSSDIDELKRKLKSLSDD 103
                 45556666551456778999999999*******************************************99866 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.56
       FAM76 212 snssdhlvavtqLkeeiaslkkqleqk 238
                       l  + q +e+i++ +++l+q 
  EEA20210.1 155 DIGRGTLADLHQQRETIERTRQNLHQS 181
                 223334444444444444444444443 PP

>> zf-C4H2  Zinc finger-containing protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   8.7     0.063        81      52     101 ..      19      69 ..      15     204 .. 0.80

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.063
     zf-C4H2  52 eeLrlIhaDina.lEsvikeaeeekekslekakklyeeykklkeevnelrs 101
                  eL+l++aD+n+ l+++ + + e+++ ++ +a+++++e ++l++++   ++
  EEA20210.1  19 AELKLVQADLNQkLDQIAETTGEQRKSAIGQAERALDEATELLDQMRMEKQ 69 
                 699*******97377777777777888899999999999999887654443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (226 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1748  (0.0974957); expected 358.6 (0.02)
Passed bias filter:                      854  (0.0476323); expected 358.6 (0.02)
Passed Vit filter:                       101  (0.00563333); expected 17.9 (0.001)
Passed Fwd filter:                        18  (0.00100396); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.66u 0.34s 00:00:01.00 Elapsed: 00:00:00.52
# Mc/sec: 1298.73
//
Query:       EEA20211.1  [L=226]
Description: vesicle transport v-snare protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.7e-22   78.9   5.5    2.7e-22   78.9   5.5    2.0  3  V-SNARE       Vesicle transport v-SNARE protein N-terminus
    3.7e-18   65.6   4.8    3.7e-18   65.6   4.8    2.6  3  V-SNARE_C     Snare region anchored in the vesicle membrane C
     0.0018   18.2   0.0     0.0035   17.2   0.0    1.5  1  Thump_like    THUMP domain-like
  ------ inclusion threshold ------
      0.048   12.3   0.6      0.062   11.9   0.6    1.3  1  DHC_N1        Dynein heavy chain, N-terminal region 1
      0.048   14.0   0.4        3.6    8.1   0.0    2.5  2  LPP           Lipoprotein leucine-zipper
      0.063   11.2   1.4       0.31    8.9   0.2    1.9  2  Prominin      Prominin
       0.64   10.0   2.7       0.59   10.1   0.2    2.2  3  Sec20         Sec20
       0.83    9.2  13.8        7.9    5.9  13.8    1.9  1  Exonuc_VII_L  Exonuclease VII, large subunit
        2.1    7.6  12.5          4    6.7  12.5    1.4  1  DUF4407       Domain of unknown function (DUF4407)
        3.7    7.9  10.7       0.78   10.0   0.1    3.3  3  YqjK          YqjK-like protein
        8.2    6.7   8.7         80    3.4   8.7    2.2  1  zf-C4H2       Zinc finger-containing protein


Domain annotation for each model (and alignments):
>> V-SNARE  Vesicle transport v-SNARE protein N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.9   5.5   1.6e-25   2.7e-22       2      78 ..      22      98 ..      21      99 .. 0.97
   2 ?   -2.4   0.1         4   6.5e+03      15      15 ..     136     136 ..     122     156 .. 0.48
   3 ?   -2.5   0.0       4.3     7e+03      23      35 ..     167     179 ..     159     195 .. 0.53

  Alignments for each domain:
  == domain 1  score: 78.9 bits;  conditional E-value: 1.6e-25
     V-SNARE  2 kellaeiksklarlsslageerkaalreiekkldeaeelldqMelEvrnlpsserasykaklreykselkklkkelk 78
                k ++a++++kl+++++ +ge+rk+a+ ++e++ldea elldqM +E +n+ps++r++++ ++r+y s++++lk++lk
  EEA20211.1 22 KLVQADLNQKLDQIAETTGEQRKSAIGQAERALDEATELLDQMRMEKQNIPSAARSKVNVRFRNYSSDIDELKRKLK 98
                6789***********************************************************************98 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 4
     V-SNARE  15 l 15 
                 l
  EEA20211.1 136 L 136
                 1 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 4.3
     V-SNARE  23 rkaalreiekkld 35 
                 +++++ +  + l 
  EEA20211.1 167 QRETIERTRQNLH 179
                 3333333333333 PP

>> V-SNARE_C  Snare region anchored in the vesicle membrane C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.1       0.7   1.1e+03      14      31 ..      51      64 ..      39     101 .. 0.58
   2 ?   -3.6   0.4       8.9   1.5e+04      33      39 ..     124     130 ..     123     131 .. 0.81
   3 !   65.6   4.8   2.3e-21   3.7e-18       1      65 [.     134     198 ..     134     199 .. 0.99

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.7
   V-SNARE_C 14 hrivdetisiGaailedL 31
                +r +      +++ l+++
  EEA20211.1 51 ERAL----DEATELLDQM 64
                3333....3333333333 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 8.9
   V-SNARE_C  33 sQretLk 39 
                 +Qr++L 
  EEA20211.1 124 EQRQQLL 130
                 7999996 PP

  == domain 3  score: 65.6 bits;  conditional E-value: 2.3e-21
   V-SNARE_C   1 erllresdrlknShrivdetisiGaailedLhsQretLkrarsklhnvanrlgksnsiLrsikrR 65 
                 erl+r+s rl++S+r++ et+ iG  +l dLh+Qret++r+r+ lh+   ++++s ++Lr + rR
  EEA20211.1 134 ERLERSSARLQESQRLALETEDIGRGTLADLHQQRETIERTRQNLHQSEGYVDTSIKTLRGMARR 198
                 79**************************************************************9 PP

>> Thump_like  THUMP domain-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   2.2e-06    0.0035       6      59 ..      60     108 ..      57     118 .. 0.81

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 2.2e-06
  Thump_like   6 vlevlpfskkklkkllrergigkanikkRgfpldpeeLrkklklkdggraatLv 59 
                  l+++ + k+++ ++ r+    k+n+  R++  d +eL++klk   +++++ L+
  EEA20211.1  60 LLDQMRMEKQNIPSAARS----KVNVRFRNYSSDIDELKRKLKSL-SDDRRALF 108
                 567888888999999866....9********************86.34355555 PP

>> DHC_N1  Dynein heavy chain, N-terminal region 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.6   3.8e-05     0.062     292     387 ..      28     124 ..       3     188 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 3.8e-05
      DHC_N1 292 Fkerikdlerrlqaiinqafeda.sslesalellrkfesllerpkikaaleekytdllqmykeeleavkklfekqkenps.aplakn.mPpvaGaiiwa 387
                  +++ +++ + +++  ++a+++a + l++a ell++++  +e+++i +a ++k +  +++y+++++++k++ ++  ++    + +++   p aG ++  
  EEA20211.1  28 LNQKLDQIAETTGEQRKSAIGQAeRALDEATELLDQMR--MEKQNIPSAARSKVNVRFRNYSSDIDELKRKLKSLSDDRRaLFGDRYtDDPEAGDVHME 124
                 45555555555666666666555234567999999999..9*******************************998887665555555555666666654 PP

>> LPP  Lipoprotein leucine-zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.5     0.069   1.1e+02      11      33 ..      27      53 ..      23      59 .. 0.61
   2 ?    8.1   0.0    0.0022       3.6       5      25 ..      86     106 ..      82     118 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.069
         LPP 11 qLkskvdqlssd....vnsakaaaqaa 33
                +L++k dq+++      +sa  +a+ a
  EEA20211.1 27 DLNQKLDQIAETtgeqRKSAIGQAERA 53
                699999999998433323333334444 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0022
         LPP   5 LssqVsqLkskvdqlssdvns 25 
                  ss++ +Lk+k ++ls+d  +
  EEA20211.1  86 YSSDIDELKRKLKSLSDDRRA 106
                 59**************99655 PP

>> Prominin  Prominin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.2   0.00019      0.31     335     417 ..      21     106 ..       8     109 .. 0.73
   2 ?    1.5   0.1     0.034        55     351     696 ..     147     191 ..     117     217 .. 0.54

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00019
    Prominin 335 lssivkeglarlneipekvknqtaevvpdlkkalakgre...qikklakkiprealdavisdlenterssktfddvvekyekyrwl 417
                 l+ +  + +++l++i e+  +q ++ + +  +al++++e   q+++++++ip+ a ++v     n  +++++ +++++ ++ +r++
  EEA20211.1  21 LKLVQADLNQKLDQIAETTGEQRKSAIGQAERALDEATElldQMRMEKQNIPSAARSKVNVRFRNYSSDIDELKRKLKSLSDDRRA 106
                 55555556778888888888888888888888888887622245556788888888888888888888888888888888888775 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.034
    Prominin 351 ekvknqtaevvpdlkkalakgreqikklakkiprealdavisdlenterssktfddvvekyekyrwliglivcsllllivvililgLlcGilGlsrtat 449
                 ++++ +t+++ +    +l+++re+i+++ +++                                                                   
  EEA20211.1 147 QRLALETEDIGRGTLADLHQQRETIERTRQNL------------------------------------------------------------------- 178
                 33344444444555555555555555555554................................................................... PP

    Prominin 450 ptdrgcskntGasfLlvgvglsFlffsllmlvvlltFlvGlnvyklvCeplesneLfrvlDtpgllpeldLsrllskklkknltisevikaCkanesif 548
                                                                                                                    
  EEA20211.1   - ---------------------------------------------------------------------------------------------------   -
                 ................................................................................................... PP

    Prominin 549 kvLrlnnlydieellnikklteeiqkelenlkvdlsnlelLteeerkdLeklresglskihsslyleqlckkltkvnletlaekleelanelsngkknl 647
                                                                                                                    
  EEA20211.1   - ---------------------------------------------------------------------------------------------------   -
                 ................................................................................................... PP

    Prominin 648 kqslkneaqdlraiqqelvlplessvkklkksvkkldeensdlqesikk 696
                                                      +++    +sik 
  EEA20211.1 179 ------------------------------------HQSEGYVDTSIKT 191
                 ....................................4433333333333 PP

>> Sec20  Sec20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1       1.4   2.3e+03      41      41 ..      53      53 ..      20      88 .. 0.56
   2 ?   -2.3   0.0       2.6   4.2e+03      23      47 ..      76      99 ..      55     103 .. 0.51
   3 ?   10.1   0.2   0.00036      0.59       9      68 ..     142     201 ..     131     210 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 1.4
       Sec20 41 l 41
                +
  EEA20211.1 53 A 53
                1 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 2.6
       Sec20 23 qSeenleeldastkslekleeeykq 47
                +S+ n+  +++ + ++ +l+ ++k+
  EEA20211.1 76 RSKVNV-RFRNYSSDIDELKRKLKS 99
                344443.355555555555555555 PP

  == domain 3  score: 10.1 bits;  conditional E-value: 0.00036
       Sec20   9 slraisqllsqevqqSeenleeldastkslekleeeykqvedvlsrskklvkklerrdkt 68 
                  l+++++l  ++ +    +l +l+++ +++e++ ++++q e+ + +s k ++ + rr +t
  EEA20211.1 142 RLQESQRLALETEDIGRGTLADLHQQRETIERTRQNLHQSEGYVDTSIKTLRGMARRYCT 201
                 5667777777777778889********************************999998775 PP

>> Exonuc_VII_L  Exonuclease VII, large subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9  13.8    0.0049       7.9     142     256 ..      18     178 ..       7     209 .. 0.58

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0049
  Exonuc_VII_L 142 kaeleeqleelerrlekaikrlleekkqrleklasrlkspeellerkrqrldeleerleralkkqlkkkrerleelkerlk................ 222
                   +ael+   ++l+++l++ ++++ e++k+ + +++++l +++ell++ r + +++ +  +++++ ++++ +++++elk++lk                
    EEA20211.1  18 EAELKLVQADLNQKLDQIAETTGEQRKSAIGQAERALDEATELLDQMRMEKQNIPSAARSKVNVRFRNYSSDIDELKRKLKslsddrralfgdrytd 114
                   4555555566667777777777788888888888888888888888888877777777777777777777777777777743555544444444444 PP

  Exonuc_VII_L 223 ............ekleekk.....erlkklkerle..................lleekkerleeleekl 256
                               +     +     erl++ ++rl+                   l++++e++e+  ++l
    EEA20211.1 115 dpeagdvhmeqrQ-----QllsgtERLERSSARLQesqrlaletedigrgtlaDLHQQRETIERTRQNL 178
                   4444333222221.....022222333333333333333334444444443333444444444444444 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7  12.5    0.0024         4     100     247 ..      20     199 ..      11     201 .. 0.66

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0024
     DUF4407 100 eLkiFekeIdaelaeeqqeeakelkeqlaaa..............ltaelaeleaqia...........alqaeidaaearldalraeaqkeldgtk.. 171
                 eLk+ + +++++l+++++ + ++ k+ + +a                                      + +  +++ ++++d+l++++++  d  +  
  EEA20211.1  20 ELKLVQADLNQKLDQIAETTGEQRKSAIGQAeraldeatelldqmR-----------MekqnipsaarsKVNVRFRNYSSDIDELKRKLKSLSDDRRal 107
                 5555666666666666666666666655555554444333222221...........122233343333333333333333333333333333333266 PP

     DUF4407 172 .gtgttgvaGkgpaakekkaqldaaqaelaelkakld...............atarlaalraelaeleaerakeraasqaaaaaddGllarl 247
                  g++ t ++  g++  e ++ql   +++l+  +a+l+                 a+l ++r+++++ ++++++++   +++++  +G++ r+
  EEA20211.1 108 fGDRYTDDPEAGDVHMEQRQQLLSGTERLERSSARLQesqrlaletedigrgTLADLHQQRETIERTRQNLHQSEGYVDTSIKTLRGMARRY 199
                 67777778888888888888888888888888888889999999999999999999999999999999999999999999999999999986 PP

>> YqjK  YqjK-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.2      0.54   8.8e+02       8      29 ..      42      64 ..      33      67 .. 0.77
   2 ?    1.8   1.5      0.18   2.9e+02       7      26 ..     124     143 ..     123     149 .. 0.87
   3 ?   10.0   0.1   0.00048      0.78       5      38 ..     164     197 ..     161     202 .. 0.88

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.54
        YqjK  8 QRl.dLaqaaepwekalapvDrg 29
                QR+ ++ qa + + +a++ +D+ 
  EEA20211.1 42 QRKsAIGQAERALDEATELLDQM 64
                55426888888899999999986 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.18
        YqjK   7 qQRldLaqaaepwekalapv 26 
                 +QR++L   +e++e+  a++
  EEA20211.1 124 EQRQQLLSGTERLERSSARL 143
                 6*************998876 PP

  == domain 3  score: 10.0 bits;  conditional E-value: 0.00048
        YqjK   5 ieqQRldLaqaaepwekalapvDrgwqtlrslrk 38 
                  +qQR+ +++  +++++    vD++++tlr + +
  EEA20211.1 164 LHQQRETIERTRQNLHQSEGYVDTSIKTLRGMAR 197
                 68***************************97644 PP

>> zf-C4H2  Zinc finger-containing protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   8.7     0.049        80      52     101 ..      19      69 ..      15     209 .. 0.80

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.049
     zf-C4H2  52 eeLrlIhaDina.lEsvikeaeeekekslekakklyeeykklkeevnelrs 101
                  eL+l++aD+n+ l+++ + + e+++ ++ +a+++++e ++l++++   ++
  EEA20211.1  19 AELKLVQADLNQkLDQIAETTGEQRKSAIGQAERALDEATELLDQMRMEKQ 69 
                 699*******97377777777777888899999999999999887654443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (226 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1209  (0.0674327); expected 358.6 (0.02)
Passed bias filter:                      588  (0.032796); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 1560.68
//
Query:       EEA20212.1  [L=457]
Description: AAA family ATPase Pontin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.1e-163  544.5   0.0   1.3e-163  544.3   0.0    1.0  1  TIP49            TIP49 P-loop domain
    2.9e-23   81.7   0.0    1.6e-22   79.4   0.0    2.2  2  TIP49_C          TIP49 AAA-lid domain
    5.1e-11   43.1   0.2    3.4e-07   30.7   0.1    2.5  2  AAA              ATPase family associated with various cellul
    5.6e-10   39.2   0.0    1.3e-06   28.3   0.0    2.4  2  RuvB_N           Holliday junction DNA helicase RuvB P-loop d
    9.5e-05   22.7   0.1       0.39   11.0   0.0    2.4  2  AAA_22           AAA domain
    0.00079   19.9   0.2     0.0061   17.0   0.2    2.2  1  AAA_16           AAA ATPase domain
    0.00087   19.7   1.2      0.064   13.6   0.3    2.3  2  AAA_19           AAA domain
    0.00092   19.2   0.1       0.19   11.8   0.0    2.5  2  AAA_5            AAA domain (dynein-related subfamily)
     0.0023   18.2   0.1     0.0048   17.2   0.1    1.5  1  AAA_28           AAA domain
     0.0023   17.6   0.1        1.2    8.8   0.0    2.3  2  Sigma54_activat  Sigma-54 interaction domain
     0.0063   15.8   0.2      0.014   14.7   0.2    1.5  1  Zeta_toxin       Zeta toxin
      0.008   15.8   0.2      0.019   14.6   0.1    1.6  2  AAA_25           AAA domain
  ------ inclusion threshold ------
      0.023   14.1   0.1       0.77    9.1   0.1    2.3  2  Mg_chelatase     Magnesium chelatase, subunit ChlI
      0.053   12.8   0.0      0.075   12.2   0.0    1.2  1  DUF2075          Uncharacterized conserved protein (DUF2075)
      0.054   13.2   0.1       0.11   12.3   0.1    1.4  1  IstB_IS21        IstB-like ATP binding protein
      0.061   12.7   0.1       0.15   11.3   0.1    1.6  1  ATPase           KaiC
      0.097   13.2   0.0       0.35   11.4   0.0    2.0  1  AAA_18           AAA domain
      0.098   12.0   0.0       0.21   10.9   0.0    1.5  1  DnaB_C           DnaB-like helicase C terminal domain
       0.13   11.8   0.2       0.44   10.0   0.0    1.9  2  AAA_7            P-loop containing dynein motor region


Domain annotation for each model (and alignments):
>> TIP49  TIP49 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  544.3   0.0  1.4e-166  1.3e-163       1     349 [.      15     368 ..      15     370 .. 0.99

  Alignments for each domain:
  == domain 1  score: 544.3 bits;  conditional E-value: 1.4e-166
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49   1 rislhshikgLGldedgeaekeeeglvGqkkareaagvivelikekklaGravLlaGpsgtGktalaiaiskelgedvpfvalsgsevyslevkktevl 99 
                 r+ +h+hikgLGl  dg+ae++++g vGq +area+gv+v+lik+kk+aGravLlaG +gtGktala+a+s+elg++vpf+ ++gse+ys+evkkte+l
  EEA20212.1  15 RTMAHTHIKGLGLRPDGTAESSADGWVGQATAREACGVVVDLIKAKKMAGRAVLLAGGPGTGKTALALAVSQELGTKVPFCPIVGSELYSAEVKKTEAL 113
                 5779*********************************************************************************************** PP

                 XXXXXXXXXXXXXX-S-EEEEEEEEEEE...-SSS-...TTS--EEEEEE-SS-EEEEEE-HHHHHHHHHHT--TT-EEEEETTT--EEE-SSS-SS-- CS
       TIP49 100 tqalrksigvrikeekevleGevveleveeaenpls.kekkikevkitlktakeekklklgskiaeellkekvkegDviviekesGkvkklGrsearak 197
                 ++++r++ig+r++e+kev+eGev+el++eeaenpl+ ++k+i++ +i lk+ k++kkl+l+++i+e+++ke+v++gDvi+ie+++G++k++Grs+a+a+
  EEA20212.1 114 MENFRRAIGLRVRETKEVYEGEVTELTPEEAENPLGgYGKTISHLIIGLKSYKGTKKLRLDPSIYEAIQKERVTVGDVIYIEANTGACKRVGRSDAYAT 212
                 ************************************9************************************************************** PP

                 ----S--------S---S----XXXXXXXXXXXXXXXXX...XXXXXXX....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49 198 efDiekdefvelPkGevekkkevvqevtLhdlDvanarp...qdllslllqllkskkteiteklreeinkkvakyveegkaeivpGvlfiDevhmlDie 293
                 efD+e++e+v++PkGev+kkke+vq+vtL dlD+anarp   qdl+s+l ql k+kkteit+klr eink+v++y+++g+ae++pGvlfiDevhmlDie
  EEA20212.1 213 EFDLEAEEYVPVPKGEVHKKKEIVQDVTLNDLDMANARPqggQDLMSMLGQLSKPKKTEITDKLRGEINKVVSRYIDQGVAELIPGVLFIDEVHMLDIE 311
                 ***************************************9999******************************************************** PP

                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49 294 cfsylnraleselaPivilatnrgiakirGt.diisphGipvDlldrlliiktekyt 349
                 cf+ylnrales++aPivila+nrg + i+Gt d++++hGip Dll rlli+ t++y+
  EEA20212.1 312 CFTYLNRALESPIAPIVILASNRGNTVIKGTgDVTAAHGIPPDLLARLLIVPTHPYS 368
                 *******************************************************97 PP

>> TIP49_C  TIP49 AAA-lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       2.4   2.3e+03      37      53 ..     324     340 ..     323     350 .. 0.81
   2 !   79.4   0.0   1.7e-25   1.6e-22       1      66 []     375     440 ..     375     440 .. 0.99

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 2.4
     TIP49_C  37 ltpasilakkrkkkeve 53 
                 ++p  ila+ r+++ ++
  EEA20212.1 324 IAPIVILASNRGNTVIK 340
                 688999*******9996 PP

  == domain 2  score: 79.4 bits;  conditional E-value: 1.7e-25
     TIP49_C   1 IlkiRakeEgvkldeeAldlLakigtetSLRYaiqLltpasilakkrkkkevevedveeveeLFlD 66 
                 I+++Rak+E++++++ Ald+ +++g++ SLRYa+qLltpasila+++++  ++v dv e+e+LF+D
  EEA20212.1 375 IIRLRAKTENLNITDPALDKVSEHGSKISLRYALQLLTPASILARVNGRPAIDVPDVTECEDLFID 440
                 9****************************************************************9 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.7   0.1   3.7e-10   3.4e-07       1      49 [.      67     117 ..      67     132 .. 0.87
   2 !   10.0   0.0   0.00095       0.9      31      70 ..     269     308 ..     255     340 .. 0.76

  Alignments for each domain:
  == domain 1  score: 30.7 bits;  conditional E-value: 3.7e-10
                 EEEESSTTSSHHHHHHHHHHHHT..HEEEEEETTTCSSSSTTHHHHHHHHH CS
         AAA   1 vllyGppGtGKTllakavakelg..vefleisgsellskyvgesekkirel 49 
                 vll G pGtGKT+la av +elg  v+f+ i gsel s  v+++e+ ++++
  EEA20212.1  67 VLLAGGPGTGKTALALAVSQELGtkVPFCPIVGSELYSAEVKKTEALMENF 117
                 79*******************954599**********99899888877765 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00095
                 TTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGH CS
         AAA  31 gsellskyvgesekkirelfkeakekakpsilfiDEidal 70 
                  +e+++k+ ge +k ++ ++++  ++  p +lfiDE++ l
  EEA20212.1 269 KTEITDKLRGEINKVVSRYIDQGVAELIPGVLFIDEVHML 308
                 56888999999999999999995444458*********87 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.3   0.0   1.3e-09   1.3e-06       7      61 ..      38      92 ..      28     103 .. 0.93
   2 !    8.2   0.0     0.002       1.9      87     117 ..     299     329 ..     290     340 .. 0.85

  Alignments for each domain:
  == domain 1  score: 28.3 bits;  conditional E-value: 1.3e-09
      RuvB_N  7 eeyigqekvkeklkifieaakkreealdhvllyGpPGlGkttlakiiakelgvkl 61
                + ++gq++ +e   ++++  k+++ a   vll+G PG Gkt+la  +++elg+k+
  EEA20212.1 38 DGWVGQATAREACGVVVDLIKAKKMAGRAVLLAGGPGTGKTALALAVSQELGTKV 92
                679************************************************9986 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.002
      RuvB_N  87 vlfideihrlsraveevlysamedfrldivi 117
                 vlfide+h l+ +   +l  a+e     ivi
  EEA20212.1 299 VLFIDEVHMLDIECFTYLNRALESPIAPIVI 329
                 9*********************988877777 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.4   0.0    0.0013       1.2       6      72 ..      65     133 ..      60     161 .. 0.60
   2 !   11.0   0.0   0.00042      0.39      59     117 ..     260     321 ..     201     339 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0013
      AAA_22   6 gilvvtGesGtGKTtllrrlleqldeeakaee..erpevv.....fvtlpsst..sskdllrellralglelka....er 72 
                 + +++ G +GtGKT l+  + ++l       +             + + +  +  + + l++++ ra+gl+  +    ++
  EEA20212.1  65 RAVLLAGGPGTGKTALALAVSQELGT-----KvpF----CpivgsELYSA--EvkKTEALMENFRRAIGLRVREtkevYE 133
                 678999*************9999942.....2221....12222322222..2335666677777777766666444444 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 0.00042
      AAA_22  59 ellralglelkaerlsseellealeqalrarav.......ielliiDEaqhlrseealeeLrslln 117
                 +l  +l  ++k+    ++ l+  +++ ++++ +       +++l iDE++ l   e++++L + l+
  EEA20212.1 260 ML-GQLSKPKKT--EITDKLRGEINKVVSRYIDqgvaeliPGVLFIDEVHML-DIECFTYLNRALE 321
                 33.333334444..456666666666666666667777778***********.9999999955444 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.2   6.5e-06    0.0061      23      56 ..      63      97 ..      52     330 .. 0.69

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 6.5e-06
      AAA_16 23 rpelvllsGesGvGKsslvrellralekdggif.l 56
                 +++vll G +G+GK++l+ ++ ++l ++  ++ +
  EEA20212.1 63 AGRAVLLAGGPGTGKTALALAVSQELGTKVPFCpI 97
                3489********************99999333333 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.6   0.3   6.8e-05     0.064       7      30 ..      61      84 ..      56      98 .. 0.81
   2 ?    4.8   0.0     0.034        32     104     125 ..     298     320 ..     150     330 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 6.8e-05
      AAA_19  7 alkekvllvtaGpGtGKTrvlkhi 30
                +++ + +l+ +GpGtGKT +  ++
  EEA20212.1 61 KMAGRAVLLAGGPGTGKTALALAV 84
                678899************976655 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.034
      AAA_19 104 ellivDEfqdvd.elqyrLlkal 125
                  +l++DE+ ++d e    L +al
  EEA20212.1 298 GVLFIDEVHMLDiECFTYLNRAL 320
                 489*********55555555554 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   0.0    0.0002      0.19       2      26 ..      67      91 ..      66     118 .. 0.84
   2 ?    4.8   0.0     0.027        25      65      90 ..     296     321 ..     266     328 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.0002
                EEEE--SSSSHHHHHHHGGGGBS-- CS
       AAA_5  2 vlLvGppGtgKselaerlaaalnre 26
                vlL G pGtgK+ la  +++ l+++
  EEA20212.1 67 VLLAGGPGTGKTALALAVSQELGTK 91
                89****************9999444 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.027
                 G-SEEEEESGGG--HHHHHHHHHHHH CS
       AAA_5  65 egeilvlDEveraesevlnsLlslle 90 
                  + +l++DEv++++ e +  L++ le
  EEA20212.1 296 IPGVLFIDEVHMLDIECFTYLNRALE 321
                 5689******************9998 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.1   5.1e-06    0.0048       2      60 ..      67     126 ..      66     143 .. 0.75

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 5.1e-06
      AAA_28   2 ivitGgestGKTtlleaLaar...gypvvpEaareileeklakgedalpwvedllafaervl 60 
                 + + Gg++tGKT l+ a +++   ++p  p ++ e+++ + +k+e  l +   + a+  rv 
  EEA20212.1  67 VLLAGGPGTGKTALALAVSQElgtKVPFCPIVGSELYSAEVKKTEA-LMEN-FRRAIGLRVR 126
                 7899***************9885556677**********9999986.5554.3344444443 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.8   0.0    0.0012       1.2      11      46 ..      53      88 ..      44     107 .. 0.78
   2 !    6.3   0.0    0.0073       6.9      95     119 ..     298     322 ..     289     327 .. 0.89

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0012
                     HHHHHHHHCTSSS-EEEECSTTSSHHHHHHHHHHHS CS
  Sigma54_activat 11 lleqikkvaktdlsvlitGesGtGKellaraiheas 46
                     +++ ik+       vl+ G  GtGK+ la a+ ++ 
       EEA20212.1 53 VVDLIKAKKMAGRAVLLAGGPGTGKTALALAVSQEL 88
                     56666777777789***************9987754 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0073
                      SEEEEETGGGS-HHHHHHHHHHHHH CS
  Sigma54_activat  95 GtlfLDeigelplelQekLlrvlqe 119
                      G+lf+De++ l++e+ + L r+l++
       EEA20212.1 298 GVLFIDEVHMLDIECFTYLNRALES 322
                      9**************9999999985 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.2   1.5e-05     0.014      18      41 ..      66      89 ..      56     102 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.5e-05
  Zeta_toxin 18 lillgGqpGAGKselaellkdele 41
                ++ll+G+pG GK++la ++ +el+
  EEA20212.1 66 AVLLAGGPGTGKTALALAVSQELG 89
                89******************9996 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.1     2e-05     0.019      31      64 ..      62      95 ..      52     124 .. 0.84
   2 ?   -3.6   0.0       7.3   6.9e+03     101     125 ..     421     446 ..     409     451 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 2e-05
      AAA_25 31 pagelallaGapgtGKttlaldlalavatGkpwl 64
                 ag  +llaG pgtGKt+lal ++ ++ t  p+ 
  EEA20212.1 62 MAGRAVLLAGGPGTGKTALALAVSQELGTKVPFC 95
                47999****************9998888888875 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 7.3
      AAA_25 101 arllvldlagv.eslpLfakdrggtl 125
                  + +++d+++v e+ +Lf + +++++
  EEA20212.1 421 NGRPAIDVPDVtECEDLFIDAKRSAT 446
                 55678889999999999998887776 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.1   0.00081      0.77      22      43 ..      64      85 ..      41     113 .. 0.83
   2 ?    2.6   0.0     0.083        78     107     132 ..     297     322 ..     286     336 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00081
  Mg_chelatase 22 gHnlllvGppGsGKtmlakrlp 43
                  g  +ll+G pG+GKt la +++
    EEA20212.1 64 GRAVLLAGGPGTGKTALALAVS 85
                  45799************98776 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.083
  Mg_chelatase 107 nGvLfLDElpefkrkvlevLRePled 132
                    GvLf+DE+  ++ + +  L + le+
    EEA20212.1 297 PGVLFIDEVHMLDIECFTYLNRALES 322
                   59********9999999999998887 PP

>> DUF2075  Uncharacterized conserved protein (DUF2075)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0     8e-05     0.075       3      51 ..      66     121 ..      64     140 .. 0.70

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 8e-05
     DUF2075   3 vvlVtGvaGtGKtvvllnllael.......eddeeertavylsvNhplvlvlreal 51 
                  vl  G++GtGKt ++l++  el           +e +++ + + ++l++  r+a+
  EEA20212.1  66 AVLLAGGPGTGKTALALAVSQELgtkvpfcPIVGSELYSAEVKKTEALMENFRRAI 121
                 57889**************9999655555533335555555666666666666555 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.1   0.00011      0.11      48      71 ..      65      88 ..      52     103 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00011
   IstB_IS21 48 enivllGpsGvGKshlaialgvea 71
                 +++l G++G+GK+ la a+++e 
  EEA20212.1 65 RAVLLAGGPGTGKTALALAVSQEL 88
                5799***************99874 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   0.00016      0.15      18      37 ..      63      82 ..      55      91 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00016
      ATPase 18 egrvvlitGepGtGKtifal 37
                 gr+vl++G+pGtGKt +al
  EEA20212.1 63 AGRAVLLAGGPGTGKTALAL 82
                689*************9986 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00037      0.35       1      24 [.      67      90 ..      67     141 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00037
      AAA_18  1 IlltGtpGvGKttlakeLskrlgf 24
                +ll+G pG+GKt la ++s++lg 
  EEA20212.1 67 VLLAGGPGTGKTALALAVSQELGT 90
                79****************999844 PP

>> DnaB_C  DnaB-like helicase C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00022      0.21      19      64 ..      64     113 ..      55     148 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00022
                 TXEEEEEEXTTSSHHHHHHHHHHHHHHCSTS.E...EEEEESSSXHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.x...xxxxxxxxxxxxxx RF
      DnaB_C  19 gdliiiAarpsmGktalalniaenaavkekl.p...vavfslemsaeqlv 64 
                 g  +++A+ p++Gktalal + ++  +k    p     ++s e ++++ +
  EEA20212.1  64 GRAVLLAGGPGTGKTALALAVSQELGTKVPFcPivgSELYSAEVKKTEAL 113
                 56789*****************9987654421222245667776666544 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00047      0.44      31      58 ..      62      89 ..      53     117 .. 0.82
   2 ?   -1.6   0.0       1.7   1.6e+03     103     116 ..     299     312 ..     297     315 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00047
       AAA_7 31 knkkpvllvGptGtGKtviikdllkkld 58
                 +++ vll G  GtGKt+++  + ++l 
  EEA20212.1 62 MAGRAVLLAGGPGTGKTALALAVSQELG 89
                56899**************999888887 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 1.7
       AAA_7 103 vvFvDDlnmpakek 116
                 v+F+D+++m   e 
  EEA20212.1 299 VLFIDEVHMLDIEC 312
                 79*******98876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (457 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       461  (0.0257125); expected 358.6 (0.02)
Passed bias filter:                      442  (0.0246528); expected 358.6 (0.02)
Passed Vit filter:                        88  (0.00490825); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              19  [number of targets reported over threshold]
# CPU time: 0.62u 0.33s 00:00:00.95 Elapsed: 00:00:00.51
# Mc/sec: 2708.84
//
Query:       EEA20213.1  [L=237]
Description: 50S ribosomal protein L24 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.7e-15   55.9   1.3    8.3e-15   54.7   1.3    1.5  1  Ribosomal_L28  Ribosomal L28 family


Domain annotation for each model (and alignments):
>> Ribosomal_L28  Ribosomal L28 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.7   1.3   4.6e-19   8.3e-15       5      59 ..      67     124 ..      65     125 .. 0.92

  Alignments for each domain:
  == domain 1  score: 54.7 bits;  conditional E-value: 4.6e-19
                    TT-.-----------S-....-SSS-BTTEEEEEEEE.TTTEEEEEEEEHHHHHH--. CS
  Ribosomal_L28   5 ltG.kkpqfGnnvshskn..kTkRtwkPNlqkvrlwseelgrkvrikvstkcLRtidk 59 
                    l+G   + fGn++s+ +n  kT+R wkPN++++++ se+lg+ v +k++ k+LRti+k
     EEA20213.1  67 LYGgVSISFGNKISKGRNkgKTRRSWKPNVRWKKMPSEALGEDVFVKLTRKALRTIRK 124
                    5666999********977668***********************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (237 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       597  (0.033298); expected 358.6 (0.02)
Passed bias filter:                      429  (0.0239277); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 1649.79
//
Query:       EEA20214.1  [L=325]
Description: alpha-1,6-mannosyltransferase subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.2e-63  213.0   0.0    7.2e-63  212.5   0.0    1.0  1  Glyco_transf_34  galactosyl transferase GMA12/MNN10 family
  ------ inclusion threshold ------
       0.23   10.8   0.4       0.32   10.3   0.4    1.1  1  DUF4407          Domain of unknown function (DUF4407)


Domain annotation for each model (and alignments):
>> Glyco_transf_34  galactosyl transferase GMA12/MNN10 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  212.5   0.0   8.1e-67   7.2e-63       4     236 ..      70     301 ..      68     304 .. 0.96

  Alignments for each domain:
  == domain 1  score: 212.5 bits;  conditional E-value: 8.1e-67
  Glyco_transf_34   4 eivlllvsnekkcenssgdhelllkvikNrvdYaekhgyeifykkvsalla...eemnsvWaklpairaamkkyPeaewiWwlDqdAlimnmdl 94 
                      ++vl+++++ +  +    d  + + + +Nr dYa +hgy +f+ ++s++l    e+++ +W ++pa+r+am++ P+  ++++lD+ A+im++ +
       EEA20214.1  70 NVVLVTLFDRQVLS----DR-YAQWIQSNREDYASRHGYATFFANTSDYLYtldEKTPRSWVQVPAVRHAMAENPHSTYFFFLDSHAFIMDPTV 158
                      79999999999986....44.8999***********************99888899************************************** PP

  Glyco_transf_34  95 sleehvlkperLeelllkntpvvplrryketnlvedgedvlviisqdwnglnagsflirnsewsklllDlwadpllrekkkavtesdeqsaley 188
                       l  hvl+p+rLe+l++k++pvvp+++ ++t+++  ++dv++ii+qd + l  gsf+i+   w++++lD+w dpl+r++++a   ++e++al +
       EEA20214.1 159 PLTSHVLEPKRLESLMIKDQPVVPPDSVIKTFSHLTPKDVELIITQDGEDLVPGSFIIKQGPWARFFLDVWYDPLYRSYNFA---RAEKHALDH 249
                      **********************************************************************************...********* PP

  Glyco_transf_34 189 llekhpevlskvglveqkvinsydegeke....lgykegdlvvhfagCkvan 236
                      ++++h+++l+k++l++q+vinsy++++++      y++gd+v+h+ +C  ++
       EEA20214.1 250 IVQWHATILAKLALIPQRVINSYSKDSPDvatdGTYHDGDFVIHLNDCDAQG 301
                      **************************999888789*************9876 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.4   3.6e-05      0.32      10      67 ..      27      84 ..      22     108 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 3.6e-05
     DUF4407 10 rkkyagiGavvlltallAalsgayAlytvlksplllallvGllwgllIfnlDRfivss 67
                r ++ ++ +++++  ++  ++++ ++++ ++ ++ ++++ G+  ++l+  +DR+++s 
  EEA20214.1 27 RRRQLKTLGIIVFALIFVLVVLSRFFSFSVSEQIAAVIPSGIANVVLVTLFDRQVLSD 84
                56666777778888888888888888888888888********************995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (325 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       850  (0.0474092); expected 358.6 (0.02)
Passed bias filter:                      647  (0.0360868); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.30s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 2111.89
//
Query:       EEA20215.1  [L=308]
Description: steroid alpha reductase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.9e-31  108.5   0.2    4.1e-31  108.0   0.2    1.2  1  Steroid_dh  3-oxo-5-alpha-steroid 4-dehydrogenase
    0.00068   20.0   0.2     0.0015   18.9   0.2    1.6  1  PEMT        Phospholipid methyltransferase
     0.0044   16.6   0.1     0.0066   16.0   0.1    1.3  1  DUF1295     Protein of unknown function (DUF1295)


Domain annotation for each model (and alignments):
>> Steroid_dh  3-oxo-5-alpha-steroid 4-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  108.0   0.2   6.9e-35   4.1e-31       2     148 ..     156     306 ..     155     308 .] 0.90

  Alignments for each domain:
  == domain 1  score: 108.0 bits;  conditional E-value: 6.9e-35
  Steroid_dh   2 kmpllivakavl.fcvlnGllqarylsyy.qpyaedylkkdrlllgivlfvlgmliniksdiiLrelrkegetkykiprgglFelvsapnyfgEilewi 98 
                 +mp ++++k+++ ++ l G+  a++++   +p a d  +   +  g++lfv+g+l n +++ iLr+lr++g t++ ip+g+ F lv++pny++Ei+ wi
  EEA20215.1 156 TMPARNIFKNCAhYWALAGVNIAYWVFRPdAPTATDDRNPILYYGGLFLFVFGELANLNAHLILRNLRRPGTTERGIPKGFGFSLVTCPNYMFEIIAWI 254
                 89*****************999988765414456666777788889***************************************************** PP

  Steroid_dh  99 g.yalvtkslaalaFalftvlnltvraaahhkwykkkf.ekYpksRkiliPf 148
                 g y l   s+  l F +    ++  +a+++ ++y+k+f +kY ++R  ++P 
  EEA20215.1 255 GvYLLTGLSWSVLLFLVLGTFQMWDWAKKKERRYRKEFgDKYKRKRFTVLPP 306
                 84556668**************************************999985 PP

>> PEMT  Phospholipid methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.2   2.4e-07    0.0015      39      97 ..     229     288 ..     196     296 .. 0.73

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 2.4e-07
        PEMT  39 mdklvtsGiYrylnnPeyvgstlgflGlaLitgsaag.lllallvllvylialkfvEeph 97 
                 ++ + +++ ++++  P y++ +++++G++L+tg  ++ ll+++l ++ ++ + k  E+++
  EEA20215.1 229 ERGIPKGFGFSLVTCPNYMFEIIAWIGVYLLTGLSWSvLLFLVLGTFQMWDWAKKKERRY 288
                 456678999************************999867778888888888888777665 PP

>> DUF1295  Protein of unknown function (DUF1295)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.1   1.1e-06    0.0066     161     195 ..     238     272 ..     196     300 .. 0.80

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 1.1e-06
     DUF1295 161 wrysRHPNYfgealiWwglflialealeglealai 195
                 +++   PNY++e++ W+g++l++  +++ l++l++
  EEA20215.1 238 FSLVTCPNYMFEIIAWIGVYLLTGLSWSVLLFLVL 272
                 566667****************9999999866655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (308 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       527  (0.0293937); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2209.27
//
Query:       EEA20216.1  [L=3986]
Description: ubiquitin-protein ligase (Tom1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   1.6e-131  438.6   0.0   1.6e-131  438.6   0.0    5.6  5  DUF913        Domain of Unknown Function (DUF913)
   4.4e-109  365.2   9.0   1.3e-108  363.6   9.0    1.9  1  DUF908        Domain of Unknown Function (DUF908)
    6.3e-95  318.2   0.0    2.3e-94  316.3   0.0    1.9  2  HECT          HECT-domain (ubiquitin-transferase)
    2.7e-29   99.7  24.9    3.8e-11   42.0   2.4    4.6  4  UBM           Ubiquitin binding region
  ------ inclusion threshold ------
       0.12   11.7   0.7       0.78    9.0   0.0    2.7  2  V-ATPase_H_N  V-ATPase subunit H
       0.14   12.1   0.4       0.81    9.7   0.1    2.5  2  UBA           UBA/TS-N domain


Domain annotation for each model (and alignments):
>> DUF913  Domain of Unknown Function (DUF913)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  438.6   0.0  5.5e-135  1.6e-131       2     368 .]     550     984 ..     549     984 .. 0.90
   2 ?    0.6   0.3     0.072   2.2e+02     270     349 ..    2040    2120 ..    1918    2126 .. 0.64
   3 ?   -8.4   8.7         6   1.8e+04     295     295 ..    2400    2400 ..    2293    2498 .. 0.46
   4 ?   -4.1   3.6         2     6e+03     275     308 ..    2818    2858 ..    2779    2905 .. 0.49
   5 ?    0.2   0.9     0.098   2.9e+02     269     320 ..    3287    3349 ..    3253    3372 .. 0.42

  Alignments for each domain:
  == domain 1  score: 438.6 bits;  conditional E-value: 5.5e-135
      DUF913   2 ravrvlDtlitniqnafqafanakgldalidrledevdealeevkegkgtpaelrssvvdyeipfqrqqlLKslLkfikhlmqssgsgtdrllrnlids 100
                 r++++lDt+++++++a+ ++a+akg+da++d++ +e+++a+++v++g g+p+e+r+++vdy+ip+++qq L++l++f++h+mq++g+g+drllrnl+ds
  EEA20216.1 550 RVLEFLDTFVHAVRDALGTLADAKGFDAISDLIGFETKSAFDNVNQGIGIPTEYRTPSVDYDIPYFQQQSLRWLFRFVNHIMQHNGGGFDRLLRNLVDS 648
                 89************************************************************************************************* PP

      DUF913 101 sqLlksLrkIienakvfGssvwslAvnilsdfihnePtslavlqeaglteslLeal........................................... 156
                 ++Ll++Lr ++enak+fGs+vws Av+ils+fihnePts+av++eagl++slLea+                                           
  EEA20216.1 649 PPLLTALRLVFENAKIFGSHVWSGAVSILSSFIHNEPTSYAVIAEAGLSKSLLEAItlkelkapeadatviteenesaiqpgassstsstaanvsycls 747
                 *************************************************************************************************** PP

      DUF913 157 ......lakgilpsrEvlasiPnvlsalcLNnaGlelfksskaleslfeifespehvkamesdgdlasnlGssfdELvRhhpsLktaiikavikmlarv 249
                       la+gi+p++E++++iP++++a+cLN+aGlelf+ss+ales+feifesp hvk+m  d +l+++lG++fdELvRhhp+Lk+++++a++ m+arv
  EEA20216.1 748 rtpdqqLARGIIPASEAMSCIPQAFGAICLNSAGLELFQSSGALESYFEIFESPVHVKCM--DANLVRSLGTTFDELVRHHPALKKSVMSAILVMVARV 844
                 ************************************************************..************************************* PP

      DUF913 250 velgkeka.....akllved...................assasskseasssssssetkeeek...............ssededvemeda....eeete 305
                   l+k++a     akl+++d                   +    s++ea + +         +               +                 +++
  EEA20216.1 845 GLLCKKMAykgagAKLWTSDgqgnltviggkhslfadigE----SFEEAVKRDG--------QftypalhegtlpnggT----------LnlgqIPDSN 921
                 ********************88888877765555543321....2222111111........12222332233333321..........0333223334 PP

      DUF913 306 sesdeseeseeekeknslldyilnvakFLeallsnnslcreFvekgGiellldlltlpslPyd 368
                  ++ +s++s++++ + ++++yi++v++FL a+++n+ +c+ F+e+gG+e++ld++tlpsl +d
  EEA20216.1 922 VQDIQSAPSDADEWGLTAANYIYPVMRFLGAFFENQVNCTYFIETGGVEFILDFATLPSLTFD 984
                 45556677888899**********************************************987 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.072
      DUF913  270 skseasssssssetkeeekssededvemeda.........eeetesesdeseeseeekeknslldyilnvakFLeall.snnslcreFve 349 
                  ++ e s++++++ ++e          em+ a         +  ++ +s+++e++  +++++++  y   + ++L+ ll s n+++ eF++
  EEA20216.1 2040 EAVEGSTANVPEPQNEP---------EMSVAetspsssiaDLGAARDSKKQEKPAFKADDHPIYIYRCFLLQCLTELLsSYNRTKVEFIN 2120
                  11111111111111111.........2222233333333322334444555666666778889999999999999999455558899984 PP

  == domain 3  score: -8.4 bits;  conditional E-value: 6
      DUF913  295 v 295 
                  v
  EEA20216.1 2400 V 2400
                  1 PP

  == domain 4  score: -4.1 bits;  conditional E-value: 2
      DUF913  275 sssssssetkeeek...........ssededvemeda...eeeteses 308 
                  +++++ ++++ee++           +  +e+    ++   +e++e+  
  EEA20216.1 2818 EEEEA-RRRREEARlekeradrlarE--EEE----REqrrKEAEEAAR 2858
                  22222.12222222222222222111..111....1111111111111 PP

  == domain 5  score: 0.2 bits;  conditional E-value: 0.098
      DUF913  269 sskseasssssssetkeeekssededvemeda.................eeetesesdeseeseeekek 320 
                  +++++as+ +++++ + ++ +++d++     +                 +e t++  ++++e+ee+++k
  EEA20216.1 3287 EKQEDASKGKEPQRPDDDD-DDDDAE-----NdsghaaaettvvrdtdmPEVTDAAGTNPSENEEKSKK 3349
                  1111111111111111111.111111.....01233344445545554433333333333333333333 PP

>> DUF908  Domain of Unknown Function (DUF908)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  363.6   9.0  4.4e-112  1.3e-108       1     358 []     114     487 ..     114     487 .. 0.91

  Alignments for each domain:
  == domain 1  score: 363.6 bits;  conditional E-value: 4.4e-112
      DUF908   1 gdkelvlaiLrftrlLLenCgNrsiYnSsehLndLLnttdldvllatLrlllrlaqrysasnkrtksasrtvqqallanhynisldrllklAqpfpktp 99 
                 gd+elv+aiL f++lL e+CgNrs+Y+Ss++LndLLntt+ ++l+ tLrl+l laqry+a  ++++ + +++qqalla hyni+ld+++kl++pfp+++
  EEA20216.1 114 GDRELVEAILSFSQLLQEKCGNRSLYSSSDRLNDLLNTTSNSLLITTLRLALLLAQRYHA--RQRNASATHFQQALLAAHYNIDLDKVQKLSSPFPRPT 210
                 69**********************************************************..777788899***************************9 PP

      DUF908 100 vsdssakaasek.......kastteyaldlvslakedskvlpsewgdvkvtYYkkssseeqkaesksskeeaseslissspstPtplrrssklgk.... 187
                 v ++   a++++       + +t+++a+d v l++e++   ++ewg+++  YY+  s++e+++++++ +e+   s + ++pstPtplrrs+++      
  EEA20216.1 211 VFGKPPGAPTSPivkakekTLQTRHDANDAVVLLREKDG--WEEWGNIRAVYYPGVSEQEKQPTETQLSEQ---SHQYQAPSTPTPLRRSATMPTprls 304
                 99987777777799**9999999************9994..*************99988877666554433...34468**************997766 PP

      DUF908 188 ..ts..sspsspaktstpskaaksqeglktfeipesevsskslyellakavekiPkesryellhririakalnssseeRqqllaiRllAitnlayihpe 282
                   +s  +sps  a+t+++  a +s+ ++k++eip+  v++++l+ +l   ++++P+esry++lhr r+a++l +s+ +R+q+l iR+lA+tnlay +pe
  EEA20216.1 305 rmSSneESPSVYAATPSSRPA-ESTRSSKLVEIPATVVAASPLETILGAKLSEVPAESRYDFLHRARVAQSLVKSDVTREQILTIRILALTNLAYLYPE 402
                 542255667766555555444.4455567********************************************************************** PP

      DUF908 283 sefqtkllkqdpd......lvyqLaeLihpe...esevprelqtaaleaLealarkkaklsdvlsaLnanvnhGiLlyvlRkava 358
                 + +q+++l+qd+d      ++yqLaeL h++   + +  r++qtaal+aL+al+++k++++dv++aLn+nvnhGiL+++ Rka+a
  EEA20216.1 403 AIMQQRILQQDSDqpkrlqITYQLAELAHLGasgDLTALRTTQTAALYALDALTKHKSRSADVCAALNVNVNHGILMFLTRKAIA 487
                 *******************************99889999********************************************96 PP

>> HECT  HECT-domain (ubiquitin-transferase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0      0.48   1.4e+03      18      63 ..    1093    1138 ..    1079    1143 .. 0.75
   2 !  316.3   0.0   7.8e-98   2.3e-94       2     306 ..    3681    3985 ..    3680    3986 .] 0.95

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.48
                  SSTTSSSEEE-TTHHHHS....HHHHHHHHHHHHHTT--BSS-B-H CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        HECT   18 esedsgtlypkpssseeellklfeflGkvlGkaiyeeilldlpfsr 63  
                  ++ +++t  +++ +  e++ +l ++lG++ + ++ +eill+ ++++
  EEA20216.1 1093 TRPSQQTSAFSQVNLTEQYTHLVTTLGQLHAACVWDEILLQKNLPQ 1138
                  3445555556655555568899******************999986 PP

  == domain 2  score: 316.3 bits;  conditional E-value: 7.8e-98
                  HHHHHHT-GGGSSEEESSTTSSSEEE-TTHHHHS.....HHHHHHHHHHHHHTT--BSS-B-HHHHHHHTT-.---TCHHHHH-HHHHHHHHHHH.. CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        HECT    2 llskelldpklglfeeesedsgtlypkpssseee.llklfeflGkvlGkaiyeeilldlpfsraflkfllgeekitledleeidpelakslkellsl 97  
                  +l++ +++p++ lf   ++d+ t++p++ s  +  +l  f+f+G+++Gka+ye+++ld +fsra++k +lg + ++++d+e +d +++ksl ++l  
  EEA20216.1 3681 VLARGMFNPNYALFIPVASDRTTFHPNRLSGVNTeHLMFFKFIGRIIGKALYEGRVLDCHFSRAVYKSILG-KSVSIKDMETLDLDYYKSLLWML-- 3774
                  68899*********99999999*****998665587789********************************.6**********************.. PP

                  HS-GGG...GT-BSEEEEE.TTEEEEEESSTTGGGSB--TTTHHHHHHHHHHHHHTGGGHHHHHHHHHHHHTTS-HHHHTTS-HHHHHHHHBCSSS. CS
                  xxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        HECT   98 esnteevedlaLtFtipen.agasatieLipnGanipVtnenkkeYiklyvnyllkksvekqleaflkGfsevipskalklfdaeelellisGedel 193 
                  e++ +++  +  tF+i+++ +g+++ i+LipnG+nipVt+enk+eY++++v+y+l  sv++qle+flkGf+++ip +++++f+++elellisG  e 
  EEA20216.1 3775 ENDITDI--ITETFAIETDdFGETQVIDLIPNGRNIPVTQENKEEYVQRVVEYKLAGSVKEQLENFLKGFHDIIPPDLISIFNEQELELLISGLPE- 3868
                  6666544..677*****99****************************************************************************9. PP

                  --HHHHHHTEEEETT--TTSHHHHHHHHHHHHS-HHHHHHHHHHHHSSSS--TTCGGG-.....B--EEEEE-S..-TTS--EEEGGGTEEEE---S CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        HECT  194 idvedlrrnteykggynaesetiewlweilkefspeekrlfLqFvTgssrlPlgGfael.....hpkftierkskedetrLPtahTCfnlLklpdYs 285 
                  idv+d+++ntey+  y+a+s++i+w+w+++++f++ee++++LqFvTg+s++Pl+Gf+el      ++f i+r    +++rLP++hTCfn+L+lp+Y+
  EEA20216.1 3869 IDVDDWKNNTEYH-NYSASSQQIQWFWRAVRSFDKEERAKLLQFVTGTSKVPLNGFKELegmngFSRFNIHRDY-GNKERLPSSHTCFNQLDLPEYE 3963
                  ************5.5********************************************9999999******66.999******************* PP

                  SHHHHHHHHHHHHHHH.H--XX CS
                  xxxxxxxxxxxxxxxx.xxxxx RF
        HECT  286 skeilkekLltAieet.egFel 306 
                  s+e l+++L  A++ + + F++
  EEA20216.1 3964 SYEDLRSRLYKAMTAGgDYFGF 3985
                  **************99788876 PP

>> UBM  Ubiquitin binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.1       2.8   8.4e+03      14      22 ..      32      40 ..      32      40 .. 0.94
   2 !   42.0   2.4   1.3e-14   3.8e-11       4      35 .]    2920    2951 ..    2917    2951 .. 0.91
   3 !   32.5   3.0   1.2e-11   3.7e-08       3      35 .]    2957    2989 ..    2955    2989 .. 0.91
   4 !   38.3   0.8     2e-13   5.9e-10       4      35 .]    3006    3038 ..    3003    3038 .. 0.87

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 2.8
         UBM 14 LaaLPpdLR 22
                La LP +LR
  EEA20216.1 32 LAQLPSHLR 40
                899*****9 PP

  == domain 2  score: 42.0 bits;  conditional E-value: 1.3e-14
         UBM    4 pppegiDpsFLaaLPpdLReEVLaqqdeeqlr 35  
                  ++ ++iDp++L+aLP+dLReEV++qq++eq++
  EEA20216.1 2920 ITGMDIDPEYLEALPEDLREEVIMQQLAEQRS 2951
                  56788*************************95 PP

  == domain 3  score: 32.5 bits;  conditional E-value: 1.2e-11
         UBM    3 apppegiDpsFLaaLPpdLReEVLaqqdeeqlr 35  
                  + +p++i  +FL+aLPp++ReE+L+ +++ ++r
  EEA20216.1 2957 GEEPTDISQEFLEALPPEIREEILQAEAAARRR 2989
                  667888***********************9997 PP

  == domain 4  score: 38.3 bits;  conditional E-value: 2e-13
         UBM    4 pppegiDp.sFLaaLPpdLReEVLaqqdeeqlr 35  
                    +e++Dp sF+a+L+p+LR+ VLa+q +e l+
  EEA20216.1 3006 AHAEEMDPaSFMATLDPSLRQSVLADQPDEILA 3038
                  44566************************9875 PP

>> V-ATPase_H_N  V-ATPase subunit H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.1      0.39   1.2e+03      13      50 ..    1623    1660 ..    1610    1670 .. 0.83
   2 ?    9.0   0.0   0.00026      0.78      99     219 ..    1818    1938 ..    1800    1940 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.39
  V-ATPase_H_N   13 rkipWegyvrsqliseedlkliksldkakkeqraklld 50  
                    r  p e++ +s +++  ++++i+ ld+ + + r+++++
    EEA20216.1 1623 RRAPSESVGQSTELRRREITTIEDLDAERDKVRKNMIE 1660
                    577889999*******************9999999876 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00026
  V-ATPase_H_N   99 kkeeqdpwkpflkllnrq..ddfivllalrllakllvqgkkksnklvesaLnrllqlLssqlssstnevieiavrllqellrtkeyRelfveadg 191 
                     +e+ ++++++l++l r   d+   l  +r+l+ l ++++      ++  L+rl+ +L+++ sss+ +++   +  l  ++  ++  ++++ +++
    EEA20216.1 1818 TDEKVQLFESLLDVLPRVgkDESLALSVCRILVILTRARHIAVRMGEKRNLQRLFVMLKQLSSSSNDKLQGAFMLILRHIVEDDDTVRQIMRSEI 1912
                    45666799*****8887668*******************99998888*************99999999999999999999999999999999888 PP

  V-ATPase_H_N  192 vstlisilrstvanstrvgiQlqYqvll 219 
                    +  + s  rs+ + +t + +  +Y+++l
    EEA20216.1 1913 TASFES--RSSRQTDTTAYVRQMYHLVL 1938
                    888877..34567778888888888887 PP

>> UBA  UBA/TS-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0      0.92   2.7e+03      20      31 ..     184     195 ..     184     196 .. 0.89
   2 ?    9.7   0.1   0.00027      0.81       2      28 ..    1478    1504 ..    1477    1505 .. 0.96

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.92
                 HHHHHHTTTSHH CS
         UBA  20 veALratgnNeE 31 
                 ++AL a+++N++
  EEA20216.1 184 QQALLAAHYNID 195
                 59********97 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.00027
                  CHHHHHHHHHTTS-HHHHHHHHHHTTT CS
         UBA    2 deeaiqrLveMGFdreevveALratgn 28  
                  ++e++++Lve G+  e + eAL++++n
  EEA20216.1 1478 NQERLNTLVERGYNLELAHEALYRCNN 1504
                  89************************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (3986 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1506  (0.083998); expected 358.6 (0.02)
Passed bias filter:                      709  (0.0395449); expected 358.6 (0.02)
Passed Vit filter:                       113  (0.00630264); expected 17.9 (0.001)
Passed Fwd filter:                        43  (0.00239835); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 2.33u 0.39s 00:00:02.72 Elapsed: 00:00:00.61
# Mc/sec: 19829.37
//
Query:       EEA20217.1  [L=320]
Description: phosphoribosyl diphosphate synthase isoform 4 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.8e-45  153.0   1.7    1.3e-43  147.6   0.1    2.4  2  Pribosyltran_N  N-terminal domain of ribose phosphate pyropho
      2e-41  142.0   5.7    1.5e-35  122.9   1.5    2.6  3  Pribosyl_synth  Phosphoribosyl synthetase-associated domain
    7.3e-19   67.8   0.8      3e-17   62.6   0.4    2.3  2  Pribosyltran    Phosphoribosyl transferase domain
    7.2e-05   22.3   0.3    0.00015   21.3   0.3    1.5  1  UPRTase         Uracil phosphoribosyltransferase


Domain annotation for each model (and alignments):
>> Pribosyltran_N  N-terminal domain of ribose phosphate pyrophosphokinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  147.6   0.1   2.9e-47   1.3e-43       1     116 []       6     123 ..       6     123 .. 0.98
   2 !    4.3   0.2    0.0082        37      13      87 ..     180     251 ..     174     257 .. 0.75

  Alignments for each domain:
  == domain 1  score: 147.6 bits;  conditional E-value: 2.9e-47
  Pribosyltran_N   1 lkifagssskeLaekiakrlgvelgkakvsrfadgEikveieesvrgkdvfiiqsls.kpvndnlmelllmidalrrasakritaViPylgysrq 94 
                     +k+++g+s++eLa+ +a+rlg+el+k+ v +++++E++v+i esvr++dvfi+qs+  +++nd lmell+mi+a+++asa+ritaViP + y+rq
      EEA20217.1   6 IKLLTGNSHPELAKLVADRLGIELTKILVLQYSNQETSVTIGESVRDEDVFILQSTKpNDINDGLMELLIMINACKTASARRITAVIPNFFYARQ 100
                     689*****************************************************9688*********************************** PP

  Pribosyltran_N  95 drk.ksrepisaklvaklLeaaG 116
                     d+k ksr+pi+a+l+a +L++aG
      EEA20217.1 101 DKKdKSRAPITARLMATMLQTAG 123
                     ***999***************99 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.0082
  Pribosyltran_N  13 aekiakrlgvelgkakvsrfadgEikveiee.svrgkdvfiiqslskpvndnlmelllmidalrrasakritaViP 87 
                     a +ia+rl+++ + ++ +r   +E++  +   +v++k  +i+ +++    d+   l+  +d++ +  ak+++a++ 
      EEA20217.1 180 ATAIADRLDLQFALIHKERARPNEVSRMVLVgNVKDKVAIIVDDMA----DTCGTLVKAADTIMEHGAKEVNAIVT 251
                     6789999999999999888888888655554388888888877766....44666777888888888888888875 PP

>> Pribosyl_synth  Phosphoribosyl synthetase-associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0       1.3   5.7e+03     103     120 ..     116     133 ..     110     137 .. 0.84
   2 !   21.2   0.0   5.3e-08   0.00024       1      37 [.     163     199 ..     163     205 .. 0.91
   3 !  122.9   1.5   3.4e-39   1.5e-35      70     183 ..     202     315 ..     197     316 .. 0.97

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 1.3
                     HHHHHHTT--EEEEEEEE CS
  Pribosyl_synth 103 aevlkerGaykiyvlath 120
                     a +l+  Ga  i+ +  h
      EEA20217.1 116 ATMLQTAGANHIITMDLH 133
                     789999999999999877 PP

  == domain 2  score: 21.2 bits;  conditional E-value: 5.3e-08
                     TGGGEEEEESSGGGHHHHHHHHHHTT-EEEEE----- CS
  Pribosyl_synth   1 dyrnavivakspgsakkatsyaerlrlglavihGeqk 37 
                     d+ n+viv+ + g ak+at+ a+rl l  a+ih e+ 
      EEA20217.1 163 DVSNCVIVSPDAGGAKRATAIADRLDLQFALIHKERA 199
                     678******************************9975 PP

  == domain 3  score: 122.9 bits;  conditional E-value: 3.4e-39
                     -------EES--TTSEEEEEEEEE-S-HHHHHHHHHHHHTT--EEEEEEEEE---TTHHHHHHHSS--EEEEESSS--HHHHHT-TTEEEE--HH CS
  Pribosyl_synth  70 kekppltvvGdvgGriaiivddliddvesfvaaaevlkerGaykiyvlathGllssdaprlleesaidevvvtntipheiqklrcskiktvdisl 164
                      e   + +vG+v+ ++aiivdd+ d   ++v+aa+++ e+Ga  + +++th +ls +a  +l++s++  +vvtnt+ph  +k  c+ki+t+dis 
      EEA20217.1 202 NEVSRMVLVGNVKDKVAIIVDDMADTCGTLVKAADTIMEHGAKEVNAIVTHAILSGNAISNLNNSCLRRLVVTNTVPHAEKKEACDKIETIDISA 296
                     5666799**************************************************************************************** PP

                     HHHHHHHHHHHT---TT-S CS
  Pribosyl_synth 165 llaeairrihngesmsylf 183
                      laea rr hnges+s+lf
      EEA20217.1 297 TLAEACRRTHNGESVSFLF 315
                     ******************9 PP

>> Pribosyltran  Phosphoribosyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0     0.011        50      43      76 ..      17      50 ..      16      70 .. 0.80
   2 !   62.6   0.4   6.8e-21     3e-17      18     125 ..     154     253 ..     151     286 .. 0.94

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.011
                  HHHHHHHHSTT-EE-EEEEEE-TTT--EE..... CS
  Pribosyltran 43 fakiladeLevplayvrkvkyrpdgseeaargss 76
                  +ak +ad+L+++l+ +++  y+++ +++++  s+
    EEA20217.1 17 LAKLVADRLGIELTKILVLQYSNQETSVTIGESV 50
                  799***********99999999888887764443 PP

  == domain 2  score: 62.6 bits;  conditional E-value: 6.8e-21
                   TTEEEEEE--GGGEEEEEEETTTHHHHHHHHHHSTT-EE-EEEEEE-TTT--EE........EE----TTSEEEEE-SEESSSHHHHHHHHHHHCC- CS
  Pribosyltran  18 laaeileeyngkpdvvvgiargGvpfakiladeLevplayvrkvkyrpdgseeaargssdesrlledpagkkVliVDDildtGgTllaalelLkekg 114
                   ++++i+e+ + ++ v+v ++ gG  +a+++ad+L++++a + k++ rp+  + ++        l +++++k  +iVDD+ dt gTl +a++ + e+g
    EEA20217.1 154 MLKWIREHLDVSNCVIVSPDAGGAKRATAIADRLDLQFALIHKERARPNEVSRMV--------LVGNVKDKVAIIVDDMADTCGTLVKAADTIMEHG 242
                   68899999999*******************************************9........9********************************* PP

                   BSEEEEEEEEE CS
  Pribosyltran 115 peevriavlvd 125
                   ++ev ++v ++
    EEA20217.1 243 AKEVNAIVTHA 253
                   ******99885 PP

>> UPRTase  Uracil phosphoribosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.3   3.3e-08   0.00015     115     183 ..     209     277 ..     178     285 .. 0.83

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 3.3e-08
     UPRTase 115 LPkkiaertvlllDpviaTGgsaaaaiqlLkergvgeekIlvlsvlaseegvkrlaeefpkvkvvtaav 183
                 L  +++++ ++++D +  T g++++a +++ e+g++e + +v   + s +++++l ++  +  vvt +v
  EEA20217.1 209 LVGNVKDKVAIIVDDMADTCGTLVKAADTIMEHGAKEVNAIVTHAILSGNAISNLNNSCLRRLVVTNTV 277
                 566789999*********************************************999888777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (320 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       617  (0.0344135); expected 358.6 (0.02)
Passed bias filter:                      459  (0.025601); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.69u 0.32s 00:00:01.01 Elapsed: 00:00:00.56
# Mc/sec: 1717.56
//
Query:       EEA20218.1  [L=237]
Description: 40S ribosomal protein S6 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.5e-56  189.0   0.1    6.5e-56  187.7   0.1    1.7  1  Ribosomal_S6e  Ribosomal protein S6e


Domain annotation for each model (and alignments):
>> Ribosomal_S6e  Ribosomal protein S6e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  187.7   0.1   3.6e-60   6.5e-56       1     125 []       1     126 [.       1     126 [. 1.00

  Alignments for each domain:
  == domain 1  score: 187.7 bits;  conditional E-value: 3.6e-60
                    -EEEEEETTTTEEEEEE-.CHHHCTTCTT-BSSEEEECCTTTSSSTS-EEEEEEEEETTC-BB-TTS-SSSEEEEEEETTSSSS-SSSSS-EEEEE CS
  Ribosomal_S6e   1 mklnisdpatgkqkliev.dekklrtligkrigeevdgdalGeelkgyvlkitggsdkqGfpmkqgvltpgrvrlLlskggvgyrprrkGerkrks 95 
                    mklnis+pa+g+qklie+ de+klr++++kr+g+ev gd lG+e+kgy++kitgg+dkqGfpmkqgvl p+rv+lLl++g+++yr rr+Gerkrks
     EEA20218.1   1 MKLNISYPANGSQKLIEIdDERKLRAFMEKRMGTEVPGDGLGDEFKGYLFKITGGNDKQGFPMKQGVLLPNRVKLLLADGHSCYRARRTGERKRKS 96 
                    9*********************************************************************************************** PP

                    EE-SB--SSEEEEEEEEEE--SS--TTTSS CS
  Ribosomal_S6e  96 vrGcivsadisqlnlvivkkgekdiegltd 125
                    +rG i  +d+++l+l ivk+ge++i+gltd
     EEA20218.1  97 IRGAITGQDLAVLALSIVKQGENEIPGLTD 126
                    *****************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (237 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       813  (0.0453455); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.31s 00:00:00.93 Elapsed: 00:00:00.54
# Mc/sec: 1312.67
//
Query:       EEA20219.1  [L=383]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (383 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       582  (0.0324614); expected 358.6 (0.02)
Passed bias filter:                      484  (0.0269954); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.71u 0.37s 00:00:01.08 Elapsed: 00:00:00.59
# Mc/sec: 1956.77
//
Query:       EEA20220.1  [L=680]
Description: HMG box transcriptional regulator, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-22   79.7   0.6    2.8e-22   78.9   0.6    1.4  1  HMG_box          HMG (high mobility group) box
    3.3e-08   34.0   0.3      7e-08   32.9   0.3    1.6  1  HMG_box_2        HMG-box domain
  ------ inclusion threshold ------
      0.048   13.0   0.0      0.098   12.0   0.0    1.5  1  MATalpha_HMGbox  Mating-type protein MAT alpha 1 HMG-box


Domain annotation for each model (and alignments):
>> HMG_box  HMG (high mobility group) box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.9   0.6   4.6e-26   2.8e-22       1      69 []     146     214 ..     146     214 .. 0.98

  Alignments for each domain:
  == domain 1  score: 78.9 bits;  conditional E-value: 4.6e-26
                 --SS--HHHHHHHHHHHHHHHHSTTS-HHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
     HMG_box   1 pkRplsafflfskeqraklkaenPelknaeiskklgekWkalseeeKkkYeekaekekaryekekpeyk 69 
                 ++Rp +af+l++++ +  ++a+nP+l n eisk++ge+W+al++e K ++++ ae+ekar+++++p+y+
  EEA20220.1 146 IPRPRNAFILYRQHYQSAVVAQNPGLANPEISKIIGEQWRALPAESKDQWKALAEAEKARHQQQYPDYR 214
                 68******************************************************************6 PP

>> HMG_box_2  HMG-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.9   0.3   1.2e-11     7e-08       6      72 ..     148     213 ..     143     214 .. 0.93

  Alignments for each domain:
  == domain 1  score: 32.9 bits;  conditional E-value: 1.2e-11
                 SS--HHHHHHHTTHHHHHHHT---SSHHHHTGGGHHHHHHS-HHHHHHHHHHHHHHHHHHHH-SS-- CS
   HMG_box_2   6 aarnAYalfvqemipelkrkGnpviglaevsklcsekWkalseeeKekYeekAkedkkrydrealty 72 
                 ++rnA++l+ q  +  + ++ np     e+sk ++e+W+al++e K +++  A + k+r +++ ++y
  EEA20220.1 148 RPRNAFILYRQHYQSAVVAQ-NPGLANPEISKIIGEQWRALPAESKDQWKALAEAEKARHQQQYPDY 213
                 789*****************.**9999**********************************987765 PP

>> MATalpha_HMGbox  Mating-type protein MAT alpha 1 HMG-box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   1.6e-05     0.098      28      91 ..     131     200 ..     105     208 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 1.6e-05
  MATalpha_HMGbox  28 veivakesreakakkakkklNgFmgfRsYy.lkLfsd...lqqkeaSgfltqlWekdp..frnkWdliak 91 
                       e++++    ++++k  ++ N+F+ +R +y +    +   l+  e+S++++  W++ p   +++W+ +a+
       EEA20220.1 131 KEVASQFCLCQPDPKIPRPRNAFILYRQHYqSAVVAQnpgLANPEISKIIGEQWRALPaeSKDQWKALAE 200
                      44555556667788888999**********8666655445999************986225778988876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (680 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       818  (0.0456244); expected 358.6 (0.02)
Passed bias filter:                      480  (0.0267723); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.81u 0.36s 00:00:01.17 Elapsed: 00:00:00.59
# Mc/sec: 3484.83
//
Query:       EEA20221.1  [L=1209]
Description: SNF2 family helicase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.5e-41  141.5   0.0    5.5e-36  124.0   0.0    2.2  2  SNF2_N      SNF2 family N-terminal domain
    6.5e-07   29.7   0.0    1.4e-06   28.6   0.0    1.5  1  Helicase_C  Helicase conserved C-terminal domain
  ------ inclusion threshold ------
      0.046   14.1   0.1       0.15   12.5   0.1    1.8  1  UPF0184     Uncharacterised protein family (UPF0184)


Domain annotation for each model (and alignments):
>> SNF2_N  SNF2 family N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  124.0   0.0   9.3e-40   5.5e-36       1     215 [.     238     534 ..     238     543 .. 0.83
   2 !   15.4   0.0     1e-06     0.006     212     342 ..     572     711 ..     549     713 .. 0.80

  Alignments for each domain:
  == domain 1  score: 124.0 bits;  conditional E-value: 9.3e-40
                 HHHHHHHHH.......................................HHHHHTT--EEE---TTS--HHHHHHHHH.....................H CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..................x RF
      SNF2_N   1 yQkeavkwmlkReqnlqdleaalrkllktldgekiyvnpatgevveesaeakqsvrGGiLaDemGLGKTvqvlalilaqr..................a 81 
                 yQ ++ + m +Re +++++  +  ++ kt  g+++y+ + +g++ +++   +++ +GGiLa+ mG GKT+ +la+il  r                   
  EEA20221.1 238 YQCRSAATMIQREVQPKQMLDPRLEVYKTPLGQEYYYDKEEGTLLRGK-RIYEEACGGILAETMGCGKTLICLAVILSTRghfpripteyqetknpfrN 335
                 9********************************************997.578999**********************8887777777553332222220 PP

                 HTTTS---.......S-............................................................................EEEE-- CS
                 xxxxxxxxxxxxxxxxx............................................................................xxxxxx RF
      SNF2_N  82 keekdkekkrkdtlagp............................................................................tLivvP 104
                                                                                                              tLi+vP
  EEA20221.1 336 ----------------SvgslmqmaaatagrfsipwpshfrrlremgvnyarceeecerhrgeytippppsrytsrggwmsrppavrirlisgTLIIVP 418
                 ................13333333455667777778888888888888888888888888888888888888888888888889999999999****** PP

                 HHHHHHHHHHHHHH-TTS-EEE--SSHHHH-----------------EEEE-HHHHHHHT..................TTS-S-S-SEEEES-GGGT-- CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............xxxxxxxxxxxxxxxxxxxxxxxx RF
      SNF2_N 105 aslldqWeneierhvsssalrvlvyggqkkmkkkntkvapklladydvvittYdvlsreaelq............kkrsvlkqvewkrvvlDEghtlkn 191
                  +l+d+W++ei+ h+++ ++ vl   ++k  +      +++ l +yd+++      ++e+e +            +  s+lk+ +w r+++DEgh++  
  EEA20221.1 419 PNLVDHWQSEIAIHTEGLNVLVLRSRNDK--T-----PSEEELLKYDIILFAR--TRFEKETGepetsrhapsisAAESPLKKFHWLRIIVDEGHNVAG 508
                 *****************987666665553..3.....3577899****99555..5555555567999******************************* PP

                 T..TSHHHHHHHH---S-EEEE-S-- CS
                 x..xxxxxxxxxxxxxxxxxxxxxxx RF
      SNF2_N 192 s..tskaaeavskLstsnrwiltGTP 215
                 +  +s++  ++ +L  ++rw+++GTP
  EEA20221.1 509 HgyKSSTMHMLDQLHVERRWVVSGTP 534
                 9999********************** PP

  == domain 2  score: 15.4 bits;  conditional E-value: 1e-06
                 -S--SSS-HHHHHHH....HHHH-TTTT--.HH....HHHHHTHHHHHHHHHHHHHHHHTT-STTEE---GGGT..--S---EEEEEEEEE--HHHHHH CS
                 xxxxxxxxxxxxxxx....xxxxxxxxxxx.xx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxx RF
      SNF2_N 212 tGTPiqnsledlygL....lkfLreepfge.kq....tfdkllqrpieaqaekgrsrLlqllqrlmlrrakkdv..eknlPpkteeiiflklskverks 299
                 tGT i ++l+d+  L    ++fL+ +p+ + ++     + k ++   e  ++ ++  L+ +lq l++r++ + +  e  lP+ +++++ l+ + +++ s
  EEA20221.1 572 TGTAIDEELKDVDNLrlivVEFLKHKPWANsRHddpaNWTKYIKPVGEDGKRRKATSLRAVLQGLVVRHRLDVIneELPLPRLHNKVVSLEPTFYDKMS 670
                 899999988887654434489*******9965588889999999888999*********************9996555688888899999988889999 PP

                 HH....................HHHHHH-HH.H-HHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxx RF
      SNF2_N 300 Ynrllevlrkkalakllkrseaalksssksk.ekilelllelrq 342
                  n  l  l+ +a+ + +k ++  ++s ++++ +    l+ +lrq
  EEA20221.1 671 INLFLFNLTVNAITSERKDQDYMFQSRNRKHlSL---LINHLRQ 711
                 9988888888888888888888888777555333...3445555 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.6   0.0   2.3e-10   1.4e-06       2     111 .]     901    1012 ..     900    1012 .. 0.86

  Alignments for each domain:
  == domain 1  score: 28.6 bits;  conditional E-value: 2.3e-10
                  HHHHHHHHHHHTTTTSEEEEEESSHHHHHH....HHHHHHHTTSTEEEESTTSTHHHHHHHHHHHH.TTSSS.EEEESGGGTSSSTSTTESEEEESS CS
  Helicase_C    2 kleallellkleeeggkilifvntidrlek....vklllekkgikvavlhgelpqnereeileqfn.kgesd.vLiatdvaerGidipkvnlVinfd 92  
                  kl +ll+ +++ ++++ki+if ++ +++      +    e  gi + ++  +l+++++ + l+ f  + +++ +L+  + a+ G+ i +++ V++++
  EEA20221.1  901 KLTYLLDRVQELHKEEKIIIFYENNNTAFWiaegL----ELLGIDFRIYANTLKTSQKAAYLSLFEeSSSVRiLLMDLRQASHGLHIASASRVFIVN 993 
                  6667777779999*************773232223....444***********************965667768899******************** PP

                  SSSSHHHHHHHHTTSSSTT CS
  Helicase_C   93 lprnvtsyiqriGRtgRag 111 
                  + + +    q+i R++R+g
  EEA20221.1  994 PIWRPYVESQAIKRAHRIG 1012
                  *****************97 PP

>> UPF0184  Uncharacterised protein family (UPF0184)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.1   2.4e-05      0.15      16      73 ..     170     225 ..     162     230 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 2.4e-05
     UPF0184  16 aeteedefgeeEyeainsmLDqinsaLDalEernDdlnskLrELlesnRqiRlefaeq 73 
                 ae++++ ++ e +  i + L++ n ++D++ +    l   ++EL+ s R++R e++e 
  EEA20221.1 170 AEQDKNAADDESLWYIFNTLENPNPTIDDVRDTDGRLA--MQELMASSREARPEVRET 225
                 567888899999999***************98777775..79************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1209 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       561  (0.0312901); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.91u 0.35s 00:00:01.26 Elapsed: 00:00:00.57
# Mc/sec: 6375.62
//
Query:       EEA20222.1  [L=607]
Description: hypothetical protein PMAA_040770 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (607 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       455  (0.0253779); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.58u 0.26s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 4182.14
//
Query:       EEA20223.1  [L=338]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0036   17.9   0.0      0.028   15.0   0.0    2.2  1  AAA_18    AAA domain
     0.0041   16.2   0.0      0.052   12.6   0.0    2.2  3  T2SSE     Type II/IV secretion system protein
     0.0045   16.7   0.0     0.0064   16.3   0.0    1.3  1  PRK       Phosphoribulokinase / Uridine kinase family
  ------ inclusion threshold ------
      0.011   16.2   0.0       0.02   15.2   0.0    1.6  1  AAA_16    AAA ATPase domain
      0.012   16.1   0.1      0.049   14.1   0.1    1.9  1  ABC_tran  ABC transporter
        0.1   12.8   0.0       0.37   10.9   0.0    2.1  1  AAA_33    AAA domain
       0.12   12.2   0.0       0.25   11.2   0.0    1.5  1  CPT       Chloramphenicol phosphotransferase-like protein
       0.14   12.0   0.0       0.34   10.8   0.0    1.6  2  MobB      Molybdopterin guanine dinucleotide synthesis protei


Domain annotation for each model (and alignments):
>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   1.3e-05     0.028       1      57 [.      20      89 ..      20     204 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.3e-05
      AAA_18  1 IlltGtpGvGKttlakeLskrlgf.gvnlrdvakenglllevdpe............aldeskrldedkl 57
                I+l+G++ +GKttla+ L    ++  ++ ++++ e++ +l++d              ++d    +d d+l
  EEA20223.1 20 IGLSGPSSSGKTTLARLLLPIFAVeNRVRTFIIHEDDFYLPDDRIpvvrtkkgelvqDWDTVGAIDVDFL 89
                89****************4443335566677777777777777665554444555555555555555555 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.0   2.3e-05     0.052     131     165 ..      19      55 ..      10      77 .. 0.74
   2 ?    0.8   0.0      0.09     2e+02      40     101 ..     114     178 ..      75     198 .. 0.78
   3 ?   -3.5   0.0       1.9   4.2e+03     126     149 ..     260     283 ..     249     298 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 2.3e-05
       T2SSE 131 lilvsGgTgsGKttllyallkeinks..derivtvED 165
                 +i +sG+ +sGKttl+  ll +++ +   + +++ ED
  EEA20223.1  19 IIGLSGPSSSGKTTLARLLLPIFAVEnrVRTFIIHED 55 
                 4558************999988766622455666677 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.09
       T2SSE  40 eelekaalerlisriaalakldiseerplqd.arlp.ekgvrlrvvllPvvagealviR.kksak 101
                 e  ++  ++ li+ ia  +k+++++ ++l d ++++    + + + ++P+++++  v+R  +++ 
  EEA20223.1 114 EAKDPGVAKDLIESIANEVKEKLNQTSLLKDeGEVTiAFLEGFLLFAPPATENPGHVLRhVHDNI 178
                 44555677889999999999999999988865777755667888999999999999999544444 PP

  == domain 3  score: -3.5 bits;  conditional E-value: 1.9
       T2SSE 126 vrerglilvsGgTgsGKttllyal 149
                 v+ +  +lv+G   +G+  l+ + 
  EEA20223.1 260 VQDHAWLLVAGDDDTGRQSLADTY 283
                 788999999999999887776544 PP

>> PRK  Phosphoribulokinase / Uridine kinase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   2.9e-06    0.0064       1      87 [.      19     102 ..      19     148 .. 0.64

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 2.9e-06
         PRK   1 vIgvagsSGaGkttvarklekifgrekvkaaeiegdsflrldrae.kdleleerkrakekevsflspeandfdllyevlkelkegkkv 87 
                 +Ig++g+S +Gktt+ar l  if+ e+   + i    +++ d  + +d  +  r +++e   +++   a+d d l + l   +e ++ 
  EEA20223.1  19 IIGLSGPSSSGKTTLARLLLPIFAVENRVRTFI----IHEDDFYLpDDRIPVVRTKKGELVQDWDTVGAIDVDFLSSALAYVREHGTL 102
                 8***********************666552222....222222221233334445555555566666666666666666666666655 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   0.0   9.1e-06      0.02      20      88 ..      13      81 ..       7     179 .. 0.65

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 9.1e-06
      AAA_16 20 rsgrpelvllsGesGvGKsslvrellralekd.ggiflrgkcdqlesaipy.....salaqalareellrqllde 88
                +sg + ++ lsG+s +GK++l+r ll  +  + ++ ++  + d++     y     ++++++ +  el+++ ++ 
  EEA20223.1 13 ASGNTIIIGLSGPSSSGKTTLARLLLPIFAVEnRVRTFIIHEDDF-----YlpddrIPVVRTKKG-ELVQDWDTV 81
                5666678889***************97444442466677777777.....323332335555533.555555555 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.1   2.2e-05     0.049      13      96 ..      19     136 ..      14     150 .. 0.72

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 2.2e-05
                 EEEEEESTTSSHHHHHHHHTTSS--SEEEE.......................EETTCEGGG......B-HHHCCHCEEEE-SS--S-TTSBHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......................xxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  13 kvaivGenGaGKStLlkllagllkpteGei.......................lldgkdlke......qeleslrkeigvlpqepqlfpeltvrenesd 82 
                 ++++ G++ +GK+tL++ll+      e ++                       +  g+ +++      ++  +l++ ++++ ++ +l p+l+ +e + +
  EEA20223.1  19 IIGLSGPSSSGKTTLARLLLPIFA-VENRVrtfiiheddfylpddripvvrtkK--GELVQDwdtvgaIDVDFLSSALAYVREHGTLPPRLRSKEDQNE 114
                 68999***************9997.57778788889999999999888886441..3333335556679999999999999999999999987777444 PP

                 TC........HHHHHHHSTTGG CS
                 xx........xxxxxxxxxxxx RF
    ABC_tran  83 ee........iekalsklglke 96 
                 ++        ie ++++++ k 
  EEA20223.1 115 AKdpgvakdlIESIANEVKEKL 136
                 4444554444555555555443 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00017      0.37       4      33 ..      22      70 ..      19     217 .. 0.68

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00017
      AAA_33  4 lvGlpGsGKstlaerl.....lkklg..avllssdt.............l 33
                l G++ sGK+tla+ l     + ++   ++++ +d+              
  EEA20223.1 22 LSGPSSSGKTTLARLLlpifaV-ENRvrTFIIHEDDfylpddripvvrtK 70
                67************99444321.222455666666655555555555550 PP

>> CPT  Chloramphenicol phosphotransferase-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   0.00011      0.25       3      25 ..      19      41 ..      16      58 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00011
                EEEEEE-TTSSHHHHHHHHHHHS CS
         CPT  3 iilLnGgsssGKsslaralqevl 25
                ii L G sssGK++lar l  ++
  EEA20223.1 19 IIGLSGPSSSGKTTLARLLLPIF 41
                677**************998776 PP

>> MobB  Molybdopterin guanine dinucleotide synthesis protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00015      0.34       1      27 [.      19      45 ..      19      62 .. 0.81
   2 ?   -3.5   0.0         4   8.9e+03      75      99 ..     133     156 ..     121     157 .. 0.54

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00015
        MobB  1 vlgivgksgsGKTtLleklipelkarg 27
                ++g+ g s sGKTtL   l+p+++ ++
  EEA20223.1 19 IIGLSGPSSSGKTTLARLLLPIFAVEN 45
                6899*****************997655 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 4
        MobB  75 eeaelsleellarlsevDlvlvEGf 99 
                 +e +l+   ll+   ev + + EGf
  EEA20223.1 133 KE-KLNQTSLLKDEGEVTIAFLEGF 156
                 33.4455555555555666666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (338 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       697  (0.0388756); expected 358.6 (0.02)
Passed bias filter:                      631  (0.0351944); expected 358.6 (0.02)
Passed Vit filter:                        77  (0.00429472); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.55u 0.31s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 2198.05
//
Query:       EEA20224.1  [L=143]
Description: pre-mRNA splicing factor Dim1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.5e-67  223.4   0.1    7.4e-67  223.2   0.1    1.0  1  DIM1         Mitosis protein DIM1
  ------ inclusion threshold ------
        0.1   12.6   0.0       0.13   12.3   0.0    1.2  1  Thioredoxin  Thioredoxin


Domain annotation for each model (and alignments):
>> DIM1  Mitosis protein DIM1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  223.2   0.1   8.2e-71   7.4e-67       1     133 []       5     137 ..       5     137 .. 0.99

  Alignments for each domain:
  == domain 1  score: 223.2 bits;  conditional E-value: 8.2e-71
                 TS-EE-SHHHHHHHHHH-SSSEEEEEEE-TT-HHHHHHHHHHHHHHHHTTTTEEEEEEETTT--TTSCCCTT-SSSEEEEEETTEEEEEE-SSS--SSB CS
        DIM1   1 llpkLetkeevdqailseeerlvviRFGrdedaeClklDelLakiaeklknfaviylvdidevpdfnkmyeledpvtilffyrnkhmkvDfgtgdnnKl 99 
                 +lp+L+++++vdqailse+erlvv+RFGrd+ ++Cl++D++L+kia+++knfaviyl+di++ pdfn myel+dp+ti+ff+rnkhm++Dfgtg+nnKl
  EEA20224.1   5 VLPHLQNAWQVDQAILSEDERLVVVRFGRDSHPDCLRQDDVLSKIADRVKNFAVIYLCDIEQTPDFNAMYELYDPMTIMFFFRNKHMMCDFGTGNNNKL 103
                 59************************************************************************************************* PP

                 -S----HHHHHHHHHHHHHHHHHT-SEEE-SS-T CS
        DIM1 100 nfvledkqelidiietiyrgakkgkglvvspidy 133
                 n+vledkqelidiietiyrgakkg+glvvsp+dy
  EEA20224.1 104 NWVLEDKQELIDIIETIYRGAKKGRGLVVSPKDY 137
                 ********************************97 PP

>> Thioredoxin  Thioredoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   1.4e-05      0.13      13      86 ..      19      92 ..       7     109 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.4e-05
                 HHTTTSSEEEEEEE-TTSHHHHCHHHHHHHHHHHCTTTSEEEEEETTTSHHHHHHTT-SSSSEEEEEETTEEEE CS
  Thioredoxin 13 evakekklvlveFyApwCghCkalaPeleklaeelkdkvklakvdvdenedlakkyevegiPtlklfkngkevk 86
                  ++++++lv+v F  +  + C +   +l k+a+++k+  +++ +d+++ +d  + ye     t+++f  +k++ 
   EEA20224.1 19 ILSEDERLVVVRFGRDSHPDCLRQDDVLSKIADRVKNFAVIYLCDIEQTPDFNAMYELYDPMTIMFFFRNKHMM 92
                 45558899****************************99999*****************9988888877766433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (143 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       398  (0.0221987); expected 358.6 (0.02)
Passed bias filter:                      356  (0.0198561); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.40u 0.24s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1084.39
//
Query:       EEA20225.1  [L=400]
Description: hypothetical protein PMAA_040800 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
      0.026   14.6   0.3      0.049   13.7   0.3    1.4  1  PTS_IIA    PTS system, Lactose/Cellobiose specific IIA subuni
       0.16   13.0   0.4        7.8    7.6   0.0    2.5  2  RNase_J_C  Ribonuclease J C-terminal domain


Domain annotation for each model (and alignments):
>> PTS_IIA  PTS system, Lactose/Cellobiose specific IIA subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.3   5.5e-06     0.049      19      57 ..     290     328 ..     281     335 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 5.5e-06
     PTS_IIA  19 eAlkaakegdfeeaeellkeAeeelkeAhkaqteliqke 57 
                  A ++a++ + e+ +el+++A+e l++Ah  + +  q++
  EEA20225.1 290 IAYRNARDWSKEKRDELIEAANERLAKAHSQHSSTTQHQ 328
                 57889999999*********************9998876 PP

>> RNase_J_C  Ribonuclease J C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   0.0   0.00087       7.8      40      66 ..     216     242 ..     205     243 .. 0.88
   2 ?    2.8   0.2     0.027   2.4e+02      13      48 ..     301     336 ..     293     343 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.00087
   RNase_J_C  40 dwnelkrkirealkkflykktkrrPmI 66 
                   ++l+r+ir++l++++   t+ rP +
  EEA20225.1 216 RPEDLNRQIRDELNHYIVPSTQIRPHV 242
                 56889*******************976 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.027
   RNase_J_C  13 keseeLieeakkvvretieealeekesdwnelkrki 48 
                 ++ +eLie+a++ ++++  ++ +++++++ +l +k+
  EEA20225.1 301 EKRDELIEAANERLAKAHSQHSSTTQHQTPDLVHKL 336
                 45579*************999999988887776665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (400 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       733  (0.0408835); expected 358.6 (0.02)
Passed bias filter:                      553  (0.0308439); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2816.31
//
Query:       EEA20226.1  [L=581]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (581 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       457  (0.0254894); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.58u 0.25s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 4061.81
//
Query:       EEA20227.1  [L=1359]
Description: xanthine dehydrogenase HxA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.1e-203  677.7   3.2   1.5e-203  677.2   3.2    1.1  1  Ald_Xan_dh_C2  Molybdopterin-binding domain of aldehyde dehyd
      3e-46  157.3   0.0    6.3e-46  156.2   0.0    1.5  1  FAD_binding_5  FAD binding domain in molybdopterin dehydrogen
      4e-34  117.3   0.0    8.3e-34  116.3   0.0    1.6  1  Ald_Xan_dh_C   Aldehyde oxidase and xanthine dehydrogenase, a
    2.9e-31  107.7   0.0    2.9e-30  104.5   0.0    2.8  3  CO_deh_flav_C  CO dehydrogenase flavoprotein C-terminal domai
    2.4e-29  101.1   0.0    5.5e-29  100.0   0.0    1.7  1  Fer2_2         [2Fe-2S] binding domain
    1.2e-07   31.5   2.5    1.3e-07   31.4   0.1    2.3  3  Fer2           2Fe-2S iron-sulfur cluster binding domain


Domain annotation for each model (and alignments):
>> Ald_Xan_dh_C2  Molybdopterin-binding domain of aldehyde dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  677.2   3.2    5e-207  1.5e-203      10     550 .]     738    1264 ..     728    1264 .. 0.98

  Alignments for each domain:
  == domain 1  score: 677.2 bits;  conditional E-value: 5e-207
                     EEEEEEE-HHHHHHH-S.EEEEEEEEEEBE---SS--EEEEEEETCTTEEEEEES-SSHHHHHHHHHHHHT--GGGEEEE-SB-S--TTTT.SS CS
  Ald_Xan_dh_C2   10 lakiekGdveaafaeadhvvegefrtgrqehfylEtqaalavpddedgeltvysstqaphevrrlvaevlglpenkvrvivprvGGGFGgK.tq 102 
                     +++i++Gd eaaf+eadhv++g  r+g+qehfylEtqa+++vp++edge++v+s+tq+p+e++++va+v+g+ +nkv+ +v+r+GGGFGgK ++
     EEA20227.1  738 FRHIKNGDTEAAFKEADHVFTGVSRMGGQEHFYLETQACVVVPKPEDGEIEVFSCTQNPTETQAYVAQVTGVAANKVVTRVKRLGGGFGGKeSR 831 
                     338999**************************************************************************************** PP

                     --HHHHHHHHHHHHHTS-EEEE--HHHHHHHS-EEEEEEEEEEEEE-TTS-EEEEEEEEEEEESSTHHHCHCCHCCTTGGGTTTB--SEEEEEE CS
  Ald_Xan_dh_C2  103 svplevlaalaAkktgrpVklvldReedmlatgkrhpfkikykvgadkdGkitaldvdlladaGayadlspavleralshldgpYkipnvrveg 196 
                     s++l+ ++a aA+kt+rpV+++l+R+ed++++g+rhpf +++kvg++k+Gkita+d+d++a+aG ++dls av+er lsh+dg+Ykipn++v+g
     EEA20227.1  832 SIQLAGICATAANKTRRPVRCMLNRDEDIITSGQRHPFLCRWKVGVTKEGKITAFDADVFANAGHTQDLSGAVVERSLSHIDGVYKIPNMHVRG 925 
                     ********************************************************************************************** PP

                     EEEE-SSS-EE-SSTTTHHHHHHHHHHHHHHHHHHHT--HHHHHHHHBCECGCC.SEEETEESSS-HHHHHHHHHHHHTHHHHHHSCCHHCCT. CS
  Ald_Xan_dh_C2  197 rvvytNtppntafRGfGgpqamfalErlmdelAeelgldplelRrrNlikpgeltpygqpvydsgdlpelldklkessdyeerraeqaefnag. 289 
                     ++++tNt++ntafRGfGgpq+mf++E++++e+A++l+++ ++lR +N++k+g+ t+y+q+  +++ +p +++++ke+s y err++++e+n++ 
     EEA20227.1  926 WLCKTNTVSNTAFRGFGGPQGMFMCESMIEEVADHLNMSSDDLRVMNMYKAGDKTHYNQE-LKDYFVPLMYKQVKEESSYVERRKAVDEYNKTh 1018
                     ***********************************************************9.699***************************888 PP

                     .ECEEEEEEEEEEEEBS--S.EETTEEEEEEEEE-TTS-EEEEESS--SSS-HHHHHHHHHHHHHT--GGGEEEE-SBTTSSS----S-TT-HH CS
  Ald_Xan_dh_C2  290 .wkkrGiglapvvegiglgftakflnqegalvrvntdGsvtvstggtemGqGletklaqiaaeeLgvpledvrvvegdtdkvpngsgtaaSrst 382 
                      w krG++++p+++gi  +fta flnq+galv++++dGs++v++ggtemGqGl+tk+ +iaa++L+vpl+dv+++e+ t++v+n+s taaS+s+
     EEA20227.1 1019 kWSKRGLSIIPTKFGI--SFTALFLNQAGALVHIYHDGSILVAHGGTEMGQGLHTKMSMIAAQALQVPLSDVHISETGTNTVANTSSTAASASS 1110
                     8***************..9999************************************************************************ PP

                     HHHHHHHHHHHHHHHHHHHHHHHHHCTS-CCCEEEETTEEEETEEEECHHHHHHHHHHTTSSEEEEEEE.......EEEETHCHCSBBEEEEEE CS
  Ald_Xan_dh_C2  383 dlngnAvkkAaeklrerllkiaaellevspedleledgkvvvkeksvslaelaaaaylervslsatgfykt....ldeetgkgppfayfaygaa 472 
                     dlng A+++A+e+++erl+++++   ++                 + +++ela+aay++rv+lsa+gfy+t    + ++++kg++f+yf++g+a
     EEA20227.1 1111 DLNGYAIYNACEQINERLRPYRE---KM----------------PNATMKELAHAAYFDRVNLSANGFYRTpdigYVWDENKGQMFYYFTQGVA 1185
                     ***********************...22................2349***************************9999*************** PP

                     EEEEEEETTT--EEEEEEEEEEE-BS-S-HHHHHHHHHHHHHHHHHHHHT---EEE.TTTEESS-STTTS----GGGS- CS
  Ald_Xan_dh_C2  473 vaeVevDtetgevkvlrvvivhDvGksiNpaivegQieGGfvqGiGlalmEelvyd.edGqlltasladYkiPtaadiP 550 
                     +aeV++Dt+tg+++ lr++i +DvG+siNp i++gQieG+f+qG Gl+++Ee ++  ++Gq++t++++ YkiP ++diP
     EEA20227.1 1186 AAEVQIDTLTGDWTPLRADIKMDVGRSINPIIDYGQIEGAFIQGQGLFTTEESLWHrATGQIFTKGPGAYKIPGFRDIP 1264
                     *******************************************************889********************9 PP

>> FAD_binding_5  FAD binding domain in molybdopterin dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  156.2   0.0   2.1e-49   6.3e-46       4     170 ..     269     444 ..     264     445 .. 0.98

  Alignments for each domain:
  == domain 1  score: 156.2 bits;  conditional E-value: 2.1e-49
                    EEEE-SSHHHHHHHHHHCTTSEEESS-TTHHHHHHHTT---SEEEEGTTSGGGS-EEEESSEEEEETTSBHHHHHHHHHHHHHHHHSH........ CS
  FAD_binding_5   4 eylrpasleealallaaepdaklvaGgtdlgvlmkekvarpehliditgipelkeieeteggleiGAavtlselaaealvrerypals........ 91 
                    +++rp +l+++l++++ +p+akl++G+t++++++k+k +r++  +++++i+elk+++ ++++le+GA+v+l++l  e +++e+++++         
     EEA20227.1 269 RWYRPVTLQQLLEIKDVYPSAKLIGGSTETQIEVKFKGLRYNPSVYVGDIAELKQYTFKDDHLELGANVSLTDL--EHICDEAVERYGpvqgqpft 362
                    6*************************************************************************..999******9999******* PP

                    ...HHHHTSS-HHHHHH-BHHHHHHHT-TT-SSHHHHHHTTEEEEEEESSEEEEEECHHHEEETTEESS-TT-EEEEEEEE- CS
  FAD_binding_5  92 ...ealekiAspqiRnvaTiGGNlataspisDlapaLlaldAevelrsaegerevpleeflkgpgktalepgelitaveiPa 170
                       ++l+ +A++qiRnva+ +GNlataspisDl+p+++a ++ ++ +s ++e+e+p+++f+kg++ tal ++ +i +++iP 
     EEA20227.1 363 aikKQLRYFAGRQIRNVASPAGNLATASPISDLNPVFVASNTVLVAKSLTKETEIPMTQFFKGYRATALPADAIIASLRIPV 444
                    *********************************************************************************6 PP

>> Ald_Xan_dh_C  Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.3   0.0   2.8e-37   8.3e-34       1     110 []     611     720 ..     611     720 .. 0.97

  Alignments for each domain:
  == domain 1  score: 116.3 bits;  conditional E-value: 2.8e-37
                   TT-SCCGGGCC-TTTE.EEEEEE-SSSSEEEEEEE-HHHHCSTTEEEEEEHHHHCCGTECCTTSSS-EEEESS-SSEESSTT-EEEEEEESSHHHHH CS
  Ald_Xan_dh_C   1 tGeavYvdDipapgal.ylafvrStkahAkivsidvsaalalpGVvavitakdlpkenkaigsiledeedallaedkvrsvgqavaavvAedeetAr 96 
                   tGea+Y+dDip+++++ y+++v+Stk++Aki+s+dv+aal++pGV++++++ dlp+   +++ +++++ ++++a d+v ++gq++++++A+++++A+
    EEA20227.1 611 TGEAQYTDDIPVQKNElYGCLVLSTKPRAKILSVDVEAALEIPGVHDYVDHRDLPSPAANWWGAPKSD-EQFFAVDEVFTAGQPIGMILANSAKIAE 706
                   8************************************************************9777777.58************************** PP

                   HHHHT-EEEEEE-- CS
  Ald_Xan_dh_C  97 kAaklvkveYeelp 110
                   +A++lvkveYeelp
    EEA20227.1 707 EAMRLVKVEYEELP 720
                   ************96 PP

>> CO_deh_flav_C  CO dehydrogenase flavoprotein C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.5   0.0   9.7e-34   2.9e-30       2     102 ..     453     555 ..     452     556 .. 0.98
   2 ?   -1.7   0.0       1.1   3.3e+03      72      93 ..     576     598 ..     569     600 .. 0.73
   3 ?   -3.3   0.0       3.5   1.1e+04      65      88 ..     951     975 ..     949     976 .. 0.84

  Alignments for each domain:
  == domain 1  score: 104.5 bits;  conditional E-value: 9.7e-34
                    EEEEESSSSSS-ESEEEEEEEEEETTCEECEEEEEEESSSSS-EE-HHHHHHHTTSBSSH.HHHHHHHHHHHTTCHHHTC.TTC-HHHHHHHHHHH CS
  CO_deh_flav_C   2 ayklsrrrendiaivnaAfrveleedgkiedariafggvaptpvraekaeaaLiGkplse.elleeaakaleeelspasd.prasaeYRrslavsl 95 
                     yk+s+r+++diaivnaA+rv+l++ +++ +a++++gg+ap +v a++ae ++iGk+l++ e+le +++alee++++  + p+++a YR++la s+
     EEA20227.1 453 VYKQSKRKDDDIAIVNAALRVSLSDTHEVLSASLVYGGMAPMTVPAKNAELYIIGKKLTNpETLEGVMNALEEDFDLGFSvPGGMATYRKTLALSF 548
                    6***********************999********************************************************************* PP

                    HHHHHHH CS
  CO_deh_flav_C  96 lfrflle 102
                    ++rf+++
     EEA20227.1 549 FYRFYHD 555
                    ****987 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 1.1
                    HTTCHHHTC.TTC-HHHHHHHHH CS
  CO_deh_flav_C  72 eeelspasd.prasaeYRrslav 93 
                    e+++s  ++  +asa+Y+++++ 
     EEA20227.1 576 ERNISSGQKdHDASAAYKQEVVG 598
                    555555555599*******9875 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 3.5
                    HHHHHHHHTTCHHHTC.TTC-HHHH CS
  CO_deh_flav_C  65 eeaakaleeelspasd.prasaeYR 88 
                    e ++++++++l+++sd +r ++ Y+
     EEA20227.1 951 ESMIEEVADHLNMSSDdLRVMNMYK 975
                    6678889999999999999999997 PP

>> Fer2_2  [2Fe-2S] binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.0   0.0   1.8e-32   5.5e-29       1      74 [.     111     183 ..     111     185 .. 0.96

  Alignments for each domain:
  == domain 1  score: 100.0 bits;  conditional E-value: 1.8e-32
      Fer2_2   1 TveglgeeleelhpvqeafveegasqCGyCtpGfvmsaaalleenepkpteeeirealsgnlCRCtgYrpivdA 74 
                 Tveg+g+  ++ hp q++++  ++sqCG+CtpG+vms++all++n+++p+++ei+ea++gnlCRCtgYrpi+d 
  EEA20227.1 111 TVEGIGDV-KNPHPAQQRMAVGNGSQCGFCTPGIVMSLYALLRNNDGEPSTDEIEEAFDGNLCRCTGYRPILDV 183
                 9*****77.679***********************************************************986 PP

>> Fer2  2Fe-2S iron-sulfur cluster binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.4   0.1   4.5e-11   1.3e-07       2      76 ..      34     100 ..      33     101 .. 0.77
   2 ?   -2.8   0.1       2.2   6.4e+03      38      44 ..     133     140 ..     131     172 .. 0.74
   3 ?   -2.8   0.0       2.1   6.2e+03       3      36 ..    1090    1122 ..    1088    1124 .. 0.70

  Alignments for each domain:
  == domain 1  score: 31.4 bits;  conditional E-value: 4.5e-11
                 ETTTEEEEEEEETTTHBHHHHHHHTTTTTSTTSSSSSSSSTTEEEEEESCECTTSSSSTHHHHHTTEE..EEGGGSE CS
        Fer2   2 tidgkevevevadgettlldaaeenggidipysCggggCgtClvevlegevqsdetelegeeldegkl..rlaCqti 76 
                 +++g++v +++ d+e tll++++  g ++++++C +ggCg+C+v v +     +   ++++         + aC ++
  EEA20227.1  34 YLNGTKVVLDEIDPELTLLEYLRGIGLTGTKLGCAEGGCGACTVVVSHI----N--PTTKKLY----HasVNACLAP 100
                 789*********************99******************98853....2..1122211....1225777665 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 2.2
                 SS.SSTTE CS
        Fer2  38 gg.CgtCl 44 
                 g+ Cg C+
  EEA20227.1 133 GSqCGFCT 140
                 444***98 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 2.1
                  TTTEEEEEEEETTTHBHHHHHHHTTTTTSTTSSS CS
        Fer2    3 idgkevevevadgettlldaaeenggidipysCg 36  
                  i  +++ +++ ++ +t   a  + +g++i  +C+
  EEA20227.1 1090 ISETGTNTVA-NTSSTAASASSDLNGYAIYNACE 1122
                  5556666655.55555888888977****99998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1359 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       670  (0.0373696); expected 358.6 (0.02)
Passed bias filter:                      590  (0.0329076); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.91u 0.33s 00:00:01.24 Elapsed: 00:00:00.50
# Mc/sec: 8105.52
//
Query:       EEA20228.1  [L=743]
Description: pheromone-regulated multispanning membrane protein Prm1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
  ------ inclusion threshold ------
        4.1    7.4  21.9        3.4    7.7   6.3    3.9  4  Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C
        4.9    6.9  10.5       0.24   11.1   0.1    3.2  4  Collagen_mid  Bacterial collagen, middle region


Domain annotation for each model (and alignments):
>> Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.1     0.028   2.5e+02      45      92 ..      85     133 ..      56     155 .. 0.53
   2 ?    7.7   0.3   0.00038       3.4      78     119 ..     163     205 ..     150     225 .. 0.72
   3 ?    7.7   6.3   0.00038       3.4      47     114 ..     436     508 ..     432     520 .. 0.76
   4 ?   -2.8   0.1      0.66   5.9e+03      77      90 ..     588     601 ..     584     611 .. 0.44

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.028
  Baculo_PEP_C  45 tqLnalsedlksllaeldtrldtll.tnLtdalnalqdtlrneLtnlns 92 
                   +++++  +++ sl   +++ +++l+ + +t+a+n l + l+  +t+++ 
    EEA20228.1  85 NSVQSAGSSMASLPHYMAQGVNELAaDGVTKAVNGLVEVLELMITGVEG 133
                   2233333444444444444565554134666777777777666666665 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.00038
  Baculo_PEP_C  78 alqdtlrneLt.nlnsiltnLlssvtNinstLnnllqalnnld 119
                   +l+++++n L+ +l si ++L + v ++++ Ln++ ++ln+++
    EEA20228.1 163 SLAEDVTNWLDqTLPSIGNDLSTAVSGVQKGLNSIGSTLNSVK 205
                   4557777777623556667788888888888888888888774 PP

  == domain 3  score: 7.7 bits;  conditional E-value: 0.00038
  Baculo_PEP_C  47 LnalsedlksllaeldtrldtlltnLtdalnalqdtlrneLtnlnsilt.n....LlssvtNinstLnnllqa 114
                   L+a+++++ +l ae+++  d++++ L++a ++ + + +  ++n+n++l+ n     ++s t +n tLn  l  
    EEA20228.1 436 LKAVEKEVPELTAEVTQFADKVINSLNNASAQWALDTNRVINNTNTDLNkNlfgwVNTSTTALNDTLNTFLDK 508
                   7788889999999999999999999999999999888888999999998442222357778888888877765 PP

  == domain 4  score: -2.8 bits;  conditional E-value: 0.66
  Baculo_PEP_C  77 nalqdtlrneLtnl 90 
                   n++++ ++n ++ l
    EEA20228.1 588 NQITEVVSNVIDKL 601
                   33333333333332 PP

>> Collagen_mid  Bacterial collagen, middle region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.3      0.03   2.7e+02      58     101 ..      83     131 ..      72     139 .. 0.69
   2 ?   11.1   0.1   2.7e-05      0.24       5      48 ..     165     208 ..     162     227 .. 0.86
   3 ?   -2.0   0.1      0.29   2.6e+03     102     113 ..     454     465 ..     435     528 .. 0.48
   4 ?   -1.7   0.1      0.23   2.1e+03     111     128 ..     584     601 ..     565     611 .. 0.58

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.03
  Collagen_mid  58 lgeavssagslVsaLgt..gp.lapl..apvttpvggvvstvgqavtsa 101
                   + + v+sags +++L +   + +  l  ++vt +v g+v+ +   +t++
    EEA20228.1  83 ACNSVQSAGSSMASLPHymAQgVNELaaDGVTKAVNGLVEVLELMITGV 131
                   5677888888888887742122445554678888888888777776665 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 2.7e-05
  Collagen_mid   5 ssqvtqglggvvtsvgnavsalgtgvsaGLGqlgetanpvGtTl 48 
                   +++vt+ l +++ s+gn +s++ +gv++GL ++g+t n+v    
    EEA20228.1 165 AEDVTNWLDQTLPSIGNDLSTAVSGVQKGLNSIGSTLNSVKSEC 208
                   56788889999***************************997655 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 0.29
  Collagen_mid 102 gttLttalssgp 113
                   ++++ ++l+++ 
    EEA20228.1 454 ADKVINSLNNAS 465
                   333333333222 PP

  == domain 4  score: -1.7 bits;  conditional E-value: 0.23
  Collagen_mid 111 sgpvqqltqqlssaitPi 128
                   s+  +q+t+ +s++i  +
    EEA20228.1 584 STTSNQITEVVSNVIDKL 601
                   444456666666666544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (743 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       849  (0.0473534); expected 358.6 (0.02)
Passed bias filter:                      582  (0.0324614); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.70u 0.28s 00:00:00.98 Elapsed: 00:00:00.44
# Mc/sec: 5048.38
//
Query:       EEA20229.1  [L=586]
Description: DNA polymerase iota, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.5e-39  133.8   0.0    8.9e-39  132.9   0.0    1.5  1  IMS       impB/mucB/samB family
    1.8e-14   54.4   0.1    4.4e-14   53.2   0.1    1.7  1  IMS_C     impB/mucB/samB family C-terminal domain
     0.0043   17.3   0.0      0.012   15.9   0.0    1.7  1  IMS_HHH   IMS family HHH motif
  ------ inclusion threshold ------
      0.075   13.6   0.0       0.23   12.1   0.0    1.8  1  HHH_5     Helix-hairpin-helix domain
       0.15   11.7   0.0       0.26   10.9   0.0    1.5  1  zf_UBZ    Ubiquitin-Binding Zinc Finger


Domain annotation for each model (and alignments):
>> IMS  impB/mucB/samB family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.9   0.0   2.5e-42   8.9e-39       2     149 ..      16     221 ..      15     222 .. 0.96

  Alignments for each domain:
  == domain 1  score: 132.9 bits;  conditional E-value: 2.5e-42
                 EETTHHHHHHHHHT.T-TTS-EEEEET....TEEEEE-HHHHTTT--TTSBHHHHHTTHTT.-EEEEEE-HHHHHHHHHHHHHHHHH-S...EEEEETT CS
         IMS   2 DmdaFyasverardpeLkgkPvvvaqgsekrgiviavsyeArayGvkrgmrikeakklcpd.livvkvdlekyrraskkileilkrfis.pkvekasiD 98 
                 D+d+Fyasv +a++p Lk  P++v+q+    +iv++++yeAr++G ++ + ikeak++cp+ +i+v  dl+k+r++sk+++ +lk f+  +k e++++D
  EEA20229.1  16 DYDCFYASVLEAENPTLKALPLAVQQK----QIVVTCNYEARRRGLRKLQLIKEAKQICPEvVIIVGEDLTKFRDVSKSLYGFLKGFTWtQKAERLGFD 110
                 9**************************....*****************************989************************87567******* PP

                 EEEEE-HHHHHHHH-S............................................................HHHHHHHHHHHHHHHH---EEEE CS
         IMS  99 Eayldltgleelaese............................................................gaalakelrkaikeelgltvsiG 137
                 E++ld+t++++ + s                                                             g++la  +r ++ +e g+t+++G
  EEA20229.1 111 EVFLDVTDMIDYNMSLlnqhdlansffcldkrdptvgfefdatgyygptypksadnplsgkvaddsqhnlaqrlilGSHLAYYMRSRLDNERGYTATVG 209
                 ********7776665578899****************************************************************************** PP

                 EESSHHHHHHHH CS
         IMS 138 iasnkllAKlas 149
                 i+++kllAKl+ 
  EEA20229.1 210 ISTSKLLAKLVG 221
                 *********985 PP

>> IMS_C  impB/mucB/samB family C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.2   0.1   1.2e-17   4.4e-14       3     116 ..     341     496 ..     339     498 .. 0.80

  Alignments for each domain:
  == domain 1  score: 53.2 bits;  conditional E-value: 1.2e-17
       IMS_C   3 earpepksissektfpepydesklkkelreLaeelarrLrdkgl................vartitlklrys..............dfh...asrsatL 68 
                 ear +p++is+e+++ +  + ++++k+l+ L+++l++r+r +                  +a++ tl+l ++              +     +srs+++
  EEA20229.1 341 EARAVPTQISIEDSYRGLEHFEDVRKQLQLLSTSLIKRMRTDLIdeevhkdtnqedgtrwIAHPRTLRLSTRrrspknadgsrdysY-AngrTSRSGPV 438
                 799**************888888****************777744444555555666667777777777555557777777775542.14669999999 PP

       IMS_C  69 .........prptsdtreileaalkLlrrlide.pglpirligvsasnlvekaesqas 116
                          +   ++++++ + +++++r+l+++    +++li+v+++n+ve a+++++
  EEA20229.1 439 pkymfslaeSAEAVAEKLVDDCLVSMFRKLHPDkAFGELSLINVAVTNMVETAGDNKQ 496
                 99***99854455*************************************99998865 PP

>> IMS_HHH  IMS family HHH motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   3.5e-06     0.012       3      29 ..     247     273 ..     246     274 .. 0.90

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 3.5e-06
     IMS_HHH   3 dvkefLwplpitkipGiGgklgekLek 29 
                 +v +fL + +i+kipGiG k ++k+++
  EEA20229.1 247 NVNRFLDDHEIGKIPGIGFKSAQKIRA 273
                 6899**************999999876 PP

>> HHH_5  Helix-hairpin-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   6.4e-05      0.23      27      52 ..     243     272 ..     237     275 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 6.4e-05
                 HHHHH....S-HHHHHTSTTS-HHHHHHHH CS
       HHH_5  27 edlaa....adveeLakipGiGkktAerii 52 
                 ed+ +    +d +e+ kipGiG k A++i 
  EEA20229.1 243 EDISNvnrfLDDHEIGKIPGIGFKSAQKIR 272
                 5555522235899***************95 PP

>> zf_UBZ  Ubiquitin-Binding Zinc Finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   7.4e-05      0.26       2      26 ..     560     584 ..     559     586 .] 0.91

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 7.4e-05
      zf_UBZ   2 tylCerCgkeipeselqEHeDwHfA 26 
                 t+lCe Cg++ip  ++  H  +H A
  EEA20229.1 560 TQLCEVCGSRIPLFAFRAHALYHAA 584
                 899****************999988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (586 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       426  (0.0237604); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.59u 0.31s 00:00:00.89 Elapsed: 00:00:00.46
# Mc/sec: 3829.43
//
Query:       EEA20230.1  [L=324]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
      0.086   12.5   5.2       0.13   11.9   5.2    1.3  1  CCDC106         Coiled-coil domain-containing protein 106
       0.32    9.2   9.3       0.34    9.1   8.4    1.4  2  CDC45           CDC45-like protein
        3.4    8.1  16.8       0.82   10.1  11.0    2.3  2  MFMR_assoc      Disordered region downstream of MFMR
          5    7.8  13.2        2.1    9.0  10.1    1.9  2  NAM-associated  No apical meristem-associated C-terminal doma


Domain annotation for each model (and alignments):
>> CCDC106  Coiled-coil domain-containing protein 106
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   5.2     3e-05      0.13      36     111 ..     176     253 ..     163     271 .. 0.51

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 3e-05
     CCDC106  36 Rcqlekfissksleaeaekeskskksekkaeksesessssseesddsssdssessessegsste...kkkkkkkk..kekk 111
                 R qle+ i++ +  +   ++s   ++ +++ +s+  + ssse+sd+ +s+s +ss+ ++  + +    ++kk+k   +e++
  EEA20230.1 176 RHQLEEEIKTVRFVT---RHSDIDSESEQEPVSDGDEASSSESSDSGDSQSDHSSSGEDDGNAQdrpMRRKKRKSapSERQ 253
                 889999998888765...333333333333444444444444444444333333322222111100022222211223333 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0      0.33   1.5e+03     392     410 ..      80      98 ..      78      99 .. 0.89
   2 ?    9.1   8.4   7.7e-05      0.34     137     205 ..     183     258 ..     154     286 .. 0.51

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 0.33
       CDC45 392 vyesFvrsygyraelsAaD 410
                 v+++F+  y+ r++lsA+D
  EEA20230.1  80 VRNTFSNAYDIRQTLSAID 98 
                 67899************99 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 7.7e-05
       CDC45 137 e......eeeeeddddeeeeeeeeedeedeeedeeeskkkrksksdeeee.sddddersrkrrrsepsakklrrql 205
                         ++++ d+++e+e  ++ de +++e++++ ++++ ++s+ e++ +++d+  +rk+r+s ps+++ r   
  EEA20230.1 183 IktvrfvTRHSDIDSESEQEPVSDGDEASSSESSDSGDSQSDHSSSGEDDgNAQDRPMRRKKRKSAPSERQIRAAA 258
                 1334444223233333333333333333333333333333333334444435555555666666667777766654 PP

>> MFMR_assoc  Disordered region downstream of MFMR
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.3      0.14   6.3e+02      87     116 ..      14      43 ..       6      74 .. 0.69
   2 ?   10.1  11.0   0.00018      0.82      28      86 ..     206     264 ..     193     282 .. 0.78

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.14
  MFMR_assoc  87 kapqtkvnqtmaivpisaakapGavlgPtt 116
                 ++p+++ + t+++++++++ a+ +v+  tt
  EEA20230.1  14 ESPSSISHTTAQKMIAITTTATPSVMHNTT 43 
                 445566666666666666666666655444 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00018
  MFMR_assoc  28 ssegsangalsqsgesesegssegSDansqndsqrkkkrsqestsqnggdakasqngae 86 
                   ++++ ++ s sg+s+s+ ss g D+  + d  +++k++++ +s+    a+a + g +
  EEA20230.1 206 DGDEASSSESSDSGDSQSDHSSSGEDDGNAQDRPMRRKKRKSAPSERQIRAAALRDGLD 264
                 4445567799*************999999999999999999998887777777666665 PP

>> NAM-associated  No apical meristem-associated C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0  10.1   0.00048       2.1      37      98 ..     196     259 ..     170     286 .. 0.67
   2 ?   -2.0   0.1       1.2   5.4e+03      30      45 ..     298     313 ..     278     321 .. 0.46

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00048
  NAM-associated  37 sspatsssestdee.dssesssesseesaadsest.sssrlkRPiGkkkaKekrkeaskdeeal 98 
                      s++++++ s+ +e +ssess++ +++s+ +s+++ + + + RP+ +kk K + +e +  ++al
      EEA20230.1 196 DSESEQEPVSDGDEaSSSESSDSGDSQSDHSSSGEdDGNAQDRPMRRKKRKSAPSERQIRAAAL 259
                     344455555556666777777777777766666551557899*********8887755545444 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.2
  NAM-associated  30 kpkssassspatssse 45 
                     + +s+++  p+t+s++
      EEA20230.1 298 ESDSKPDTIPSTQSPS 313
                     2233333333333332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (324 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1001  (0.0558313); expected 358.6 (0.02)
Passed bias filter:                      531  (0.0296168); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 2281.81
//
Query:       EEA20231.1  [L=84]
Description: hypothetical protein PMAA_040900 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
      0.012   15.4   0.0      0.015   15.1   0.0    1.2  1  Serum_albumin  Serum albumin family


Domain annotation for each model (and alignments):
>> Serum_albumin  Serum albumin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.1   0.0   8.4e-07     0.015      20      88 ..       7      75 ..       2      80 .. 0.80

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 8.4e-07
                   HHHHHHSTTS-HHHHHHHHHHHHHHHHHHHCT.TTCHHHHCHHHHHHHHHHHTGTTHTHCCCTHHHHHGS CS
  Serum_albumin 20 iklsqklpqatfeelsklvkdvtkvaekCckl.edaleCaedeaslllekiCekqelspksskvkeCCek 88
                   ++ s kl + t +el++l +   + ++    +  d+leC++d  +++l+  C   e +p  + + eCC +
     EEA20231.1  7 VRRSWKLDSQTKQELVSLFEATYNGTKPIEFSnGDTLECLHDGDETILGASCGGGEGQPRLG-FGECCGE 75
                   6666677777888888888877776665555557*******************999998888.*****75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (84 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       405  (0.0225891); expected 358.6 (0.02)
Passed bias filter:                      252  (0.0140554); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.29s 00:00:00.72 Elapsed: 00:00:00.48
# Mc/sec: 522.29
//
Query:       EEA20232.1  [L=452]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.7e-05   21.4   0.1     0.0058   15.6   0.0    2.1  2  Tri3          15-O-acetyltransferase Tri3
  ------ inclusion threshold ------
       0.12   11.7   0.0       0.19   11.0   0.0    1.2  1  SUa-2TM       SMODS- and Ubiquitin system-associated 2TM effe
       0.19   10.3   0.1       0.55    8.8   0.0    1.7  2  Condensation  Condensation domain


Domain annotation for each model (and alignments):
>> Tri3  15-O-acetyltransferase Tri3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    3.6   0.0    0.0042        25      60      93 ..      49      82 ..      36     118 .. 0.67
   2 !   15.6   0.0   9.8e-07    0.0058     175     314 ..     137     275 ..     129     310 .. 0.75

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.0042
        Tri3 60 tvltlsslkeklerallearfkhPeiaatvlWde 93
                 ++++ +l   +++a    rfkhP iaa v+ + 
  EEA20232.1 49 GSIAMEDLISLFREAWKALRFKHPTIAAYVMDET 82
                456677788889999999**********998664 PP

  == domain 2  score: 15.6 bits;  conditional E-value: 9.8e-07
        Tri3 175 hsnhlyfdGiskrlfvGdllrslaellgteqkppelkWGeevknlgapvldllkldvealGdefddkldeyvaalvrntqsyGlrfkpdl....GlPrv 269
                 h+ h   dG+   + + d+l   +    +  + + l WGee + l++++ ++  l   +  +e ++  ++ va    ++++ G+  ++      G  r+
  EEA20232.1 137 HAQHWRTDGVGGFMPMDDFLDLASR--SVPVDTSSLPWGEETRRLAPSIEEAAGLLSATTSEEDKKLAQQTVAGFGLTVGAIGIASHAAAetvpGGTRI 233
                 8889999999999999999976666..66777899***************9998877777777666777778777778899999887654223366799 PP

        Tri3 270 ilhtltaeeseaiikavksrlgPkytiahlghaavvlallkakkP 314
                     l+ +e++a++ka k +     +++   ha+v  a      P
  EEA20232.1 234 SCLQLSEQETNAVVKACKDKQ---ISVTAAVHASVAGANYALAAP 275
                 99****************875...444444555554444444444 PP

>> SUa-2TM  SMODS- and Ubiquitin system-associated 2TM effector domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   3.3e-05      0.19     208     242 ..      17      51 ..       3      65 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 3.3e-05
     SUa-2TM 208 yNeefikeikklvrklpedistiNifattnPkntv 242
                  Ne fik +    r+l+ +   iN+ at+ P+  +
  EEA20232.1  17 DNETFIKMLADSARQLNREHWAINVVATVTPMGSI 51 
                 59*****************************9766 PP

>> Condensation  Condensation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0      0.35   2.1e+03      38      88 ..      54     103 ..      31     118 .. 0.63
   2 ?    8.8   0.0   9.2e-05      0.55     396     433 ..     411     448 ..     403     451 .. 0.89

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 0.35
                   ---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T CS
  Condensation  38 eldlerlekalqelierhdaLRtvfleeengepvQvileerevelevleis 88 
                   e  ++++++a+++l  +h+++     ++e+  ++ v +e++ +e+ ++ ++
    EEA20232.1  54 EDLISLFREAWKALRFKHPTIAAYV-MDETRYIYDVPDETALTEWATETFR 103
                   3345588999999998888887666.4546666666666666666666655 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 9.2e-05
                   EEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHH CS
  Condensation 396 easetngkltikieYntslFdeetierflerlkelleq 433
                   ++++  ++l++++ Yn++ ++++t++ f   +k+ll+q
    EEA20232.1 411 HVWTFRNELYLNLVYNEAFYEKATMDAFVGSVKDLLLQ 448
                   56667789***************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (452 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       476  (0.0265492); expected 358.6 (0.02)
Passed bias filter:                      428  (0.0238719); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 2866.39
//
Query:       EEA20233.1  [L=229]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (229 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1125  (0.0627475); expected 358.6 (0.02)
Passed bias filter:                      352  (0.019633); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.55u 0.32s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 1454.88
//
Query:       EEA20234.1  [L=182]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-07   30.8   0.0    3.7e-07   29.8   0.0    1.6  2  Cupin_2   Cupin domain
     0.0015   18.2   0.0     0.0021   17.7   0.0    1.2  1  Cupin_1   Cupin


Domain annotation for each model (and alignments):
>> Cupin_2  Cupin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.8   0.0   4.1e-11   3.7e-07       2      68 ..      90     156 ..      89     159 .. 0.87
   2 ?   -2.1   0.0      0.37   3.3e+03      35      50 ..     161     176 ..     154     179 .. 0.72

  Alignments for each domain:
  == domain 1  score: 29.8 bits;  conditional E-value: 4.1e-11
                 EEEEETTEEEEEECSSSEEEEEEEEESEEEEEEC.TEEEEEETTEEEEE-TT-EEEEEE-SSS.-EEEE CS
     Cupin_2   2 lvelppGesapshrHpgedeffyVleGegeltvd.geeveleaGdsvyfpagtpHrfrNtgde.parll 68 
                 +v l pG  +p+hr      +++V eGe+ l +d ge+ ++++Gd+ ++ +gt H++rN++++  ar++
  EEA20234.1  90 VVDLNPGSLSPMHRTLSL-DYGVVMEGEIDLLLDsGEVRHMKRGDI-IIQRGTMHAWRNPSKTdWARVF 156
                 6899**********8888.*************88799********6.6899*********988556555 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.37
                 CTEEEEEETTEEEEE- CS
     Cupin_2  35 dgeeveleaGdsvyfp 50 
                 ++++v+le+G ++  +
  EEA20234.1 161 ESQPVQLEDGKTLGED 176
                 5778999999877655 PP

>> Cupin_1  Cupin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0   2.3e-07    0.0021      26     111 ..      78     156 ..      74     172 .. 0.79

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 2.3e-07
                 TTTHSSTEEEEEEEE..TTEEEEEEEESSS-EEEEEEESEEEEEEEETTSS.EEEEEEEETTEEEEE-TT-EEEEEEESSSSEEEEE CS
     Cupin_1  26 pglntlgisaarvdl.epgglllPhyhpnateiayvlqGegrvgfvvpgngnrdfhkklreGdvfvvPaglvhfqynsgdepavaiv 111
                 pgl   g+s++rv+  +pg+l+++h +  +    +v++Ge +  ++ +g+      + +++Gd+++  +g +h++ n  +++   ++
  EEA20234.1  78 PGLTVPGGSVLRVVDlNPGSLSPMHRT-LSLDYGVVMEGEID-LLLDSGE-----VRHMKRGDIII-QRGTMHAWRNPSKTDWARVF 156
                 5666668899999888***********.9*************.8888885.....66699***875.6**********966643332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (182 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       220  (0.0122706); expected 358.6 (0.02)
Passed bias filter:                      216  (0.0120475); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.46
# Mc/sec: 1186.84
//
Query:       EEA20235.1  [L=72]
Description: hypothetical protein PMAA_040940 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (72 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       363  (0.0202465); expected 358.6 (0.02)
Passed bias filter:                      241  (0.0134419); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.37u 0.30s 00:00:00.67 Elapsed: 00:00:00.43
# Mc/sec: 499.52
//
Query:       EEA20236.1  [L=802]
Description: ADAM family of metalloprotease ADM-B [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.5e-61  208.0   6.3    1.5e-61  208.0   6.3    2.1  2  Reprolysin_5     Metallo-peptidase family M12
    1.3e-49  168.6   1.7    2.5e-49  167.7   1.7    1.4  1  Reprolysin_4     Metallo-peptidase family M12B Reprolysin-lik
    1.1e-46  159.2   2.4    2.7e-46  157.9   2.4    1.7  1  Reprolysin_2     Metallo-peptidase family M12B Reprolysin-lik
    1.1e-16   61.4  31.2    1.1e-16   61.4  31.2    4.4  3  Disintegrin      Disintegrin
    6.2e-10   39.7   0.5    2.2e-09   37.9   0.0    2.3  2  Reprolysin_3     Metallo-peptidase family M12B Reprolysin-lik
    3.4e-06   27.5  12.1    3.4e-06   27.5  12.1    4.3  3  ADAM_CR_2        ADAM cysteine-rich domain
     0.0023   18.1   0.0     0.0047   17.2   0.0    1.4  1  Pep_M12B_propep  Reprolysin family propeptide
  ------ inclusion threshold ------
      0.093   11.7   0.0       0.16   10.9   0.0    1.3  1  Peptidase_M66    Peptidase M66


Domain annotation for each model (and alignments):
>> Reprolysin_5  Metallo-peptidase family M12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  208.0   6.3   6.9e-65   1.5e-61       2     196 .]     273     476 ..     272     476 .. 0.95
   2 ?   -7.1   5.4         8   1.8e+04     164     174 ..     528     547 ..     507     574 .. 0.66

  Alignments for each domain:
  == domain 1  score: 208.0 bits;  conditional E-value: 6.9e-65
  Reprolysin_5   2 trtvall.vaaDcsfvaafggda.aaqanivnlvnrasnvyeresnislglanvtildeedpstase......asstgdaselLnefqsassalrgq 90 
                   +r val+ va+Dc+f +afg++  aa+a +++++n+as+vyer++nislgl+n+t+++ e+p+ +s+      ++ +g++s++L++f    +a+rg+
    EEA20236.1 273 SRLVALVgVATDCNFLNAFGNNEsAARADVISMFNSASSVYERTFNISLGLKNLTMSPAECPDVPSKaapwnlPCTSGNVSSRLSDF----TAWRGE 365
                   6889***************66557****************************************999********************....9***** PP

  Reprolysin_5  91 qnddlailflmtnfsgg..vGlAwlgqlcnsgsagsvstrveksnsvvvstatevqvvaHElGHnfGavHDcdsss.......esqsCslsnstepa 178
                   q+d++a+++lmtn++++  vG++wlgqlc +gs  +        ++vvv+tate+qv+aHE+GH+fGavHDcd s+       +sq+C+l++st++a
    EEA20236.1 366 QSDENAYWTLMTNCPTNseVGVSWLGQLCVHGSTNASVAG----ANVVVKTATEWQVFAHETGHTFGAVHDCDPSAcqqglqtTSQCCPLTSSTCNA 458
                   ****************99************9985555555....799***************************99********************* PP

  Reprolysin_5 179 ggryiMapssspnstdfS 196
                   +g+y+M+ps+ +n+++fS
    EEA20236.1 459 NGQYLMNPSTASNLENFS 476
                   *****************8 PP

  == domain 2  score: -7.1 bits;  conditional E-value: 8
  Reprolysin_5 164 s...esqsCslsn......s 174
                   +   ++++C++++      +
    EEA20236.1 528 AgcgDNACCDPTTckfknsA 547
                   35555666666544444343 PP

>> Reprolysin_4  Metallo-peptidase family M12B Reprolysin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  167.7   1.7   1.1e-52   2.5e-49       4     197 ..     276     484 ..     273     493 .. 0.93

  Alignments for each domain:
  == domain 1  score: 167.7 bits;  conditional E-value: 1.1e-52
  Reprolysin_4   4 vvrvavavdpeyvael.gsvdevraainalvtvlnevYgrdlnvrLeli....sdqdviytdsetdsfaadisgedlgnsslatltstrdskdyDla 95 
                   v++v+va+d+++ + + ++  ++ra ++ + + ++ vY+r++n++L l     s  +++  +s+++++++ + ++++  s+l  +t++r+++ + +a
    EEA20236.1 276 VALVGVATDCNFLNAFgNNESAARADVISMFNSASSVYERTFNISLGLKnltmSPAECPDVPSKAAPWNLPCTSGNV-SSRLSDFTAWRGEQSDENA 371
                   899*************6667789************************999999**********************99.9****************** PP

  Reprolysin_4  96 allrdtr.asqqnvgvawvgalcls.arq.nk.kasgvaasrdeydifAHEiGHtfGaaHdls...........degeglsskteegsgqtIMsyas 177
                   +++++t  + + +vgv+w+g+lc+  + + +  +a++v ++  e+++fAHE GHtfGa+Hd++           +++++l+s+t++++gq++M++  
    EEA20236.1 372 YWTLMTNcPTNSEVGVSWLGQLCVHgSTNaSVaGANVVVKTATEWQVFAHETGHTFGAVHDCDpsacqqglqttSQCCPLTSSTCNANGQYLMNPST 468
                   *******9***************99877765547799999999****************************************************99 PP

  Reprolysin_4 178 easqeafapisirliavsic 197
                     + e+f+++++ +i    c
    EEA20236.1 469 ASNLENFSQCTVGNI----C 484
                   9999********999....2 PP

>> Reprolysin_2  Metallo-peptidase family M12B Reprolysin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  157.9   2.4   1.2e-49   2.7e-46       3     192 ..     297     487 ..     295     489 .. 0.90

  Alignments for each domain:
  == domain 1  score: 157.9 bits;  conditional E-value: 1.2e-49
  Reprolysin_2   3 avteelvnvlnrvnqiYeeddinislrlrn....eaeieatteasdsgnnycnssttevrrlnllsqlegekdydlahlvllgtf.sggvlGLayvg 94 
                   a+++ +++++n+++ +Ye  ++nisl+l+n    +ae+++ ++  +++n  c s   +  rl  + +++ge+ + +a+++l++++ +++++G  ++g
    EEA20236.1 297 AARADVISMFNSASSVYE-RTFNISLGLKNltmsPAECPDVPSKAAPWNLPCTSGNVS-SRLSDFTAWRGEQSDENAYWTLMTNCpTNSEVGVSWLG 391
                   578899************.**********99999****************99999885.59************************************ PP

  Reprolysin_2  95 qicqkeassrktntglsttansgsaveetkeidvvaHEvGHaFGatHdndgs.......sasegveenaatsvedaggkfiMapasksnndlFSpcs 184
                   q+c +++++     +++     +  v++ +e++v+aHE GH+FGa+Hd+d s       ++s++++ ++ t  ++a+g+++M+p+ +sn  +FS c+
    EEA20236.1 392 QLCVHGSTN----ASVA---GANVVVKTATEWQVFAHETGHTFGAVHDCDPSacqqglqTTSQCCPLTSST--CNANGQYLMNPSTASNLENFSQCT 479
                   ***888888....3222...3335566699********************998888888777788999988..************************ PP

  Reprolysin_2 185 islisdvl 192
                   +++i+++ 
    EEA20236.1 480 VGNICSAI 487
                   *****876 PP

>> Disintegrin  Disintegrin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   9.3         1   2.3e+03      20      67 ..     433     485 ..     423     511 .. 0.68
   2 !   61.4  31.2   4.8e-20   1.1e-16       1      76 []     517     592 ..     517     592 .. 0.95
   3 ?  -11.0  18.0         8   1.8e+04      23      44 ..     621     645 ..     596     688 .. 0.40

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 1
  Disintegrin  20 cdaktCkl..kkgaqC..sageCckekCkl.ksagtvCreakdeeCdleeyCd 67 
                  cd++ C+   ++++qC   +++ c+++ ++ ++ +t    ++ ++C++ ++C+
   EEA20236.1 433 CDPSACQQglQTTSQCcpLTSSTCNANGQYlMNPSTASNLENFSQCTVGNICS 485
                  66666665446677776644666666766634455555555666788888886 PP

  == domain 2  score: 61.4 bits;  conditional E-value: 4.8e-20
  Disintegrin   1 eegEecDcGaeeeckkdkCcdaktCklkkgaqC..sageCckekCklksagtvCreakdeeCdleeyCdGksaeCped 76 
                  e+gE+cDcG ++ c +++Ccd++tCk+k++a+C  s+++Cc+  C++k+a+t+Cr+++   Cd++e+C+G+s +Cp+d
   EEA20236.1 517 ESGEDCDCGGTAGCGDNACCDPTTCKFKNSAVCddSNEPCCS-GCQFKTANTTCRASTGP-CDIAEVCSGTSGSCPAD 592
                  78*******9999*88*****************8777*****.6************9888.***************97 PP

  == domain 3  score: -11.0 bits;  conditional E-value: 8
  Disintegrin  23 ktCklkkgaqC..sageCckek.Ck 44 
                  ++C+   ga+   +++  c+++ C+
   EEA20236.1 621 QQCRTILGAVLgsNDTYACDDSsCT 645
                  3333333332221112222211122 PP

>> Reprolysin_3  Metallo-peptidase family M12B Reprolysin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.9   0.0   9.9e-13   2.2e-09       2     124 .]     300     432 ..     299     432 .. 0.70
   2 ?   -3.2   0.1         5   1.1e+04      59      84 ..     487     516 ..     456     542 .. 0.58

  Alignments for each domain:
  == domain 1  score: 37.9 bits;  conditional E-value: 9.9e-13
  Reprolysin_3   2 aaiaalvnranqiyerdlgirlqlvaiiitdkasdpytkkdatealdelaevtae...........aergqagyDlvhlftardesgvgGlAyvgsv 87 
                   a++++++n a+++yer+++i+l l+++  +  +  + ++k a ++l  ++ +++            +   +++    +l+t+    +  G+ ++g++
    EEA20236.1 300 ADVISMFNSASSVYERTFNISLGLKNLTMSPAECPDVPSKAAPWNLPCTSGNVSSrlsdftawrgeQ---SDENAYWTLMTNCPTNSEVGVSWLGQL 393
                   67899********************887665553333333334444444444444344444343213...333333444455444799********* PP

  Reprolysin_3  88 cnsskkagvnsgssvlgkvga..dtvaHEiGHnfganHt 124
                   c  +++ ++++g +v+ k+    +++aHE GH fga H+
    EEA20236.1 394 CVHGSTNASVAGANVVVKTATewQVFAHETGHTFGAVHD 432
                   ******99999999999976678***************7 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 5
  Reprolysin_3  59 rgqagyDlvhlftarde....sgvgGlAyv 84 
                   +g++++    l++++d+    ++ +G   v
    EEA20236.1 487 IGRNSVRSNCLVNNKDVvtytGSQCGNGIV 516
                   555555555556666665555555555544 PP

>> ADAM_CR_2  ADAM cysteine-rich domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?  -18.0  19.8         8   1.8e+04      29      60 ..     482     513 ..     424     541 .. 0.60
   2 ?  -23.5  28.7         8   1.8e+04      43      59 ..     547     563 ..     505     617 .. 0.52
   3 !   27.5  12.1   1.5e-09   3.4e-06       2      70 .]     614     683 ..     613     683 .. 0.89

  Alignments for each domain:
  == domain 1  score: -18.0 bits;  conditional E-value: 8
   ADAM_CR_2  29 svCsklwCskdgkektclt..kkvpaadgTsCgs 60 
                 ++Cs +  +  +  ++cl   k v ++ g++Cg+
  EEA20236.1 482 NICSAIGRNSVR--SNCLVnnKDVVTYTGSQCGN 513
                 444443333322..33333113345555555554 PP

  == domain 2  score: -23.5 bits;  conditional E-value: 8
   ADAM_CR_2  43 ktcltkkvpaadgTsCg 59 
                 + c  ++ p   g + +
  EEA20236.1 547 AVCDDSNEPCCSGCQFK 563
                 45544444444442222 PP

  == domain 3  score: 27.5 bits;  conditional E-value: 1.5e-09
   ADAM_CR_2   2 GelysadeQCrlafgseskkcpaekeesvCsklwCskdgk.ektcltkkvpaadgTsCgskkwClkgkCv 70 
                 G+  s+++QCr + g    + ++ + ++   +lwC  +   +++c ++++  +dgT+C+ + +C +g+C+
  EEA20236.1 614 GQCTSRNQQCRTILGAVLGSNDTYACDDSSCTLWCASSILpSNQCVSMQQNFLDGTPCNGDGHCDNGQCM 683
                 9999***********98877777765555558*****888899**************************6 PP

>> Pep_M12B_propep  Reprolysin family propeptide
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   2.1e-06    0.0047      24      91 ..      47     112 ..      28     126 .. 0.77

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 2.1e-06
  Pep_M12B_propep  24 rrRslseeeekeerlsyrlkafgkefhLnLepnsellapgftvethredgeereesp.qeeehCyYqGe 91 
                      ++R  s+   ++  + + ++ + +  +L+Lepn+++la+++ v++ + dg+ r++++ ++++h +++G+
       EEA20236.1  47 SHRIHSQ---SNFDITFTIHNHAEPIKLKLEPNHDVLAEDAEVQYLNADGTIRHTESiDRRDHRVFKGS 112
                      4444432...247899999999**********************9999888777655477778888886 PP

>> Peptidase_M66  Peptidase M66
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   7.1e-05      0.16     175     259 ..     396     482 ..     351     498 .. 0.64

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 7.1e-05
  Peptidase_M66 175 hGGlgggssG..ivtgdatltgefiHEqGHalGLpHylageaaskgsypyaegsllgseWGyDanhneflsnllaktse.yknckkes 259
                    hG    + +G  +v+  at  ++f HE+GH +G  H    +a ++g     +   l s+    an ++++++ +a++ e +++c   +
     EEA20236.1 396 HGSTNASVAGanVVVKTATEWQVFAHETGHTFGAVHDCDPSACQQGLQTTSQCCPLTSS-TCNANGQYLMNPSTASNLEnFSQCTVGN 482
                    55555555551146667777899*************88777777775444444444443.2456666666666665555566666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (802 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       797  (0.0444531); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.76u 0.27s 00:00:01.03 Elapsed: 00:00:00.49
# Mc/sec: 4921.85
//
Query:       EEA20237.1  [L=277]
Description: cell division control protein Cdc31, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-16   60.5   2.5    2.6e-10   40.6   0.2    2.2  2  EF-hand_7        EF-hand domain pair
    4.4e-15   54.0   0.7    1.4e-05   24.3   0.0    3.6  4  EF-hand_1        EF hand
    7.8e-14   50.4   4.5    6.7e-06   25.6   0.1    3.8  4  EF-hand_6        EF-hand domain
      5e-11   42.3   3.4    1.6e-08   34.2   0.2    2.9  3  EF-hand_8        EF-hand domain pair
     0.0017   17.8   1.1        1.5    8.4   0.1    3.3  3  EF-hand_5        EF hand
  ------ inclusion threshold ------
      0.041   14.1   0.0          1    9.6   0.0    2.2  2  DUF3572          Protein of unknown function (DUF3572)
      0.047   13.6   0.0       0.13   12.2   0.0    1.7  2  EF-hand_4        Cytoskeletal-regulatory complex EF hand
       0.17   12.0   0.1       0.57   10.3   0.0    1.9  2  EFhand_Ca_insen  Ca2+ insensitive EF hand
        8.4    5.8  13.7       0.18   11.3   5.5    2.0  2  DUF5560          Family of unknown function (DUF5560)


Domain annotation for each model (and alignments):
>> EF-hand_7  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   0.2   3.2e-07   0.00064       2      48 ..     102     142 ..     101     147 .. 0.89
   2 !   40.6   0.2   1.3e-13   2.6e-10       2      70 ..     212     275 ..     211     276 .. 0.90

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 3.2e-07
   EF-hand_7   2 eklkeaFkelDtdgdgyldkeellrllrkifqgagegsklsdeelel 48 
                 e++ eaF ++D d+d +ld+ el+ +lr        g+ l+++el  
  EEA20237.1 102 EEINEAFTLFDLDRDRHLDYHELRVALR------ALGFTLPKQELIS 142
                 899*********************9999......8999999988755 PP

  == domain 2  score: 40.6 bits;  conditional E-value: 1.3e-13
   EF-hand_7   2 eklkeaFkelDtdgdgyldkeellrllrkifqgagegsklsdeelellfkefDtdkdGvisfdEFlkly 70 
                 e++ +aF+++D  g gy+d e+l+r+ r +    ge+  l ++el+++++efD+ + G +++d Fl ++
  EEA20237.1 212 EEILRAFELFDEGGKGYIDLEDLRRVAREL----GET-GLEEDELRAMIEEFDLEGVGGVTRDGFLSIC 275
                 7899************************95....444.447899*********************9876 PP

>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.3   0.0   7.1e-09   1.4e-05       1      29 []     103     131 ..     103     131 .. 0.95
   2 ?   -3.8   0.0       6.5   1.3e+04      20      27 ..     138     145 ..     136     146 .. 0.80
   3 !   19.2   0.1     3e-07   0.00059       1      28 [.     213     240 ..     213     241 .. 0.91
   4 !    7.1   0.0    0.0022       4.5       1      20 [.     250     269 ..     250     276 .. 0.87

  Alignments for each domain:
  == domain 1  score: 24.3 bits;  conditional E-value: 7.1e-09
                 HHHHHHHHHTTTSSSEEEHHHHHHHHHHH CS
   EF-hand_1   1 elkeiFrefDkDgdGkIdfeEfkellkkl 29 
                 e++e+F +fD D+d ++d+ E++ +l++l
  EEA20237.1 103 EINEAFTLFDLDRDRHLDYHELRVALRAL 131
                 799**********************9975 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 6.5
                 HHHHHHHH CS
   EF-hand_1  20 eEfkellk 27 
                 +E+++ll+
  EEA20237.1 138 QELISLLT 145
                 89999986 PP

  == domain 3  score: 19.2 bits;  conditional E-value: 3e-07
                 HHHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1   1 elkeiFrefDkDgdGkIdfeEfkellkk 28 
                 e+ ++F++fD  g G+Id+e+++++ ++
  EEA20237.1 213 EILRAFELFDEGGKGYIDLEDLRRVARE 240
                 6789*******************99775 PP

  == domain 4  score: 7.1 bits;  conditional E-value: 0.0022
                 HHHHHHHHHTTTSSSEEEHH CS
   EF-hand_1   1 elkeiFrefDkDgdGkIdfe 20 
                 el+ +++efD  g G ++++
  EEA20237.1 250 ELRAMIEEFDLEGVGGVTRD 269
                 799**********9999876 PP

>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.1   3.4e-09   6.7e-06       1      31 []     103     132 ..     103     132 .. 0.96
   2 ?   -1.5   0.0       1.7   3.4e+03      17      29 ..     135     146 ..     134     148 .. 0.78
   3 !   22.6   0.1   3.3e-08   6.5e-05       1      31 []     213     242 ..     213     242 .. 0.91
   4 ?    1.2   0.0      0.24   4.7e+02       2      24 ..     251     273 ..     250     275 .. 0.74

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 3.4e-09
   EF-hand_6   1 elreaFklfDkdgdGkidaeElrkalrkalg 31 
                 e++eaF lfD d+d ++d++Elr alr alg
  EEA20237.1 103 EINEAFTLFDLDRDRHLDYHELRVALR-ALG 132
                 699************************.887 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1.7
   EF-hand_6  17 idaeElrkalrka 29 
                 + ++El+++l+  
  EEA20237.1 135 LPKQELISLLT-T 146
                 6789*****99.4 PP

  == domain 3  score: 22.6 bits;  conditional E-value: 3.3e-08
   EF-hand_6   1 elreaFklfDkdgdGkidaeElrkalrkalg 31 
                 e+ +aF+lfD  g G+id e+lr++ r +lg
  EEA20237.1 213 EILRAFELFDEGGKGYIDLEDLRRVAR-ELG 242
                 5789********************999.776 PP

  == domain 4  score: 1.2 bits;  conditional E-value: 0.24
   EF-hand_6   2 lreaFklfDkdgdGkidaeElrk 24 
                 lr+  ++fD +g G ++++ + +
  EEA20237.1 251 LRAMIEEFDLEGVGGVTRDGFLS 273
                 66666789999999998887765 PP

>> EF-hand_8  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.2   0.2    0.0022       4.4      26      52 ..     102     128 ..     100     131 .. 0.89
   2 ?    3.3   0.0     0.038        75       6      32 ..     120     144 ..     116     146 .. 0.83
   3 !   34.2   0.2   8.1e-12   1.6e-08       2      49 ..     226     272 ..     225     274 .. 0.94

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0022
   EF-hand_8  26 eevdilfrefDtdgdGkisfeEFcvll 52 
                 ee+ + f +fD+d+d ++++ E  v l
  EEA20237.1 102 EEINEAFTLFDLDRDRHLDYHELRVAL 128
                 799************999999988776 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.038
   EF-hand_8   6 treelrrilrilglkkglseeevdilf 32 
                 + +elr +lr+lg    l ++e+ +l+
  EEA20237.1 120 DYHELRVALRALGFT--LPKQELISLL 144
                 668*********999..9999976665 PP

  == domain 3  score: 34.2 bits;  conditional E-value: 8.1e-12
   EF-hand_8   2 kgkItreelrrilrilglkkglseeevdilfrefDtdgdGkisfeEFc 49 
                 kg+I+ e+lrr +r lg   gl e+e+++++ efD++g G ++ + F+
  EEA20237.1 226 KGYIDLEDLRRVARELGET-GLEEDELRAMIEEFDLEGVGGVTRDGFL 272
                 8**********99999988.6************************997 PP

>> EF-hand_5  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.3   0.0    0.0037       7.3       1      22 [.     104     125 ..     104     128 .. 0.83
   2 !    8.4   0.1   0.00076       1.5       1      24 [.     215     237 ..     215     238 .. 0.91
   3 ?   -1.4   0.0      0.99     2e+03      12      17 ..     268     273 ..     266     274 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0037
                 HHHHHHHH-SS-SSCE-HHHHH CS
   EF-hand_5   1 lkdtFqaiDlNgDGkIskeELk 22 
                 ++++F  +Dl++D +++  EL+
  EEA20237.1 104 INEAFTLFDLDRDRHLDYHELR 125
                 6888*********777777776 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.00076
                 HHHHHHHH-SS-SSCE-HHHHHHH CS
   EF-hand_5   1 lkdtFqaiDlNgDGkIskeELktl 24 
                 l++ F+ +D  g G+I+ e L+++
  EEA20237.1 215 LRA-FELFDEGGKGYIDLEDLRRV 237
                 567.******************97 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.99
                 -SSCE- CS
   EF-hand_5  12 gDGkIs 17 
                 +DG++s
  EEA20237.1 268 RDGFLS 273
                 8***99 PP

>> DUF3572  Protein of unknown function (DUF3572)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.12   2.3e+02       7      26 ..     126     144 ..     123     162 .. 0.77
   2 ?    9.6   0.0   0.00053         1      18      43 ..     233     258 ..     228     263 .. 0.86

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.12
     DUF3572   7 lAlaaLawlagdpellgrFL 26 
                 +Al+aL++ + ++el++  L
  EEA20237.1 126 VALRALGFTLPKQELISL-L 144
                 8*********99998864.4 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00053
     DUF3572  18 dpellgrFLaltGlepadLRaaaaep 43 
                 d +++ r L++tGle+++LRa+++e 
  EEA20237.1 233 DLRRVARELGETGLEEDELRAMIEEF 258
                 66788999**************9985 PP

>> EF-hand_4  Cytoskeletal-regulatory complex EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   6.7e-05      0.13      41      71 ..     100     130 ..      86     154 .. 0.78
   2 ?   -2.6   0.0       2.7   5.3e+03      30      50 ..     236     256 ..     211     271 .. 0.62

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 6.7e-05
   EF-hand_4  41 eedklekiwdladidedgkldfeefciamrl 71 
                 + +++++ ++l d+d d +ld++e+ +a+r 
  EEA20237.1 100 QREEINEAFTLFDLDRDRHLDYHELRVALRA 130
                 3345666789******************995 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 2.7
   EF-hand_4  30 kvapvlknskleedklekiwd 50 
                 +va  l ++ leed+l  + +
  EEA20237.1 236 RVARELGETGLEEDELRAMIE 256
                 455556666666666666555 PP

>> EFhand_Ca_insen  Ca2+ insensitive EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       2.1   4.1e+03       5      16 ..     101     112 ..      99     129 .. 0.64
   2 ?   10.3   0.0   0.00029      0.57       4      29 ..     210     236 ..     207     243 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 2.1
                      HHHHHCHHHHHC CS
  EFhand_Ca_insen   5 aeqveeaFrala 16 
                      +e++ eaF    
       EEA20237.1 101 REEINEAFTLFD 112
                      588888886554 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00029
                      THHHHHCHHHHH.CTTSSSEEHHHHHH CS
  EFhand_Ca_insen   4 saeqveeaFral.aggKpYvTeedLrr 29 
                       +e+++ aF    +ggK Y+  edLrr
       EEA20237.1 210 PREEILRAFELFdEGGKGYIDLEDLRR 236
                      579*********9************97 PP

>> DUF5560  Family of unknown function (DUF5560)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   5.5   8.8e-05      0.18      56     118 ..      34      97 ..       3     104 .. 0.77
   2 ?   -0.7   1.2      0.43   8.5e+02      70     116 ..     148     196 ..     132     205 .. 0.57

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 8.8e-05
     DUF5560  56 aflaqstlles.tlegapewaaphpeeqrrsppacsqhtpplpstptgpppcspggnhplcals 118
                 af  +  +l     +  pe a p+p +   +pp  sq      +t  gp  +s gg  pl  l+
  EEA20237.1  34 AFSRNRGVLGGvNNNNNPESAQPQPSQLPPAPPQHSQSHAGAVATMMGPADASSGGANPLSRLT 97 
                 55544444443145678********************9999*******************9886 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.43
     DUF5560  70 gapewaaphpeeqrrsp..pacsqhtpplpstp.tgpppcspggnhplca 116
                 g p     + ++q++ p  p++s h p  p      ppp       pl a
  EEA20237.1 148 GVPRPQVQQQQQQQQGPgqPSASAH-PNKPNNNnKDPPPHPSSLLMPLSA 196
                 5555555555555555522555555.444544404455544444556655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (277 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       546  (0.0304535); expected 358.6 (0.02)
Passed bias filter:                      367  (0.0204696); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2082.79
//
Query:       EEA20238.1  [L=534]
Description: AAA family ATPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.8e-58  197.2   0.1    3.2e-58  196.4   0.1    1.4  1  MgsA_C           MgsA AAA+ ATPase C terminal
      8e-23   80.6   0.4    3.4e-22   78.6   0.1    2.2  2  AAA_assoc_2      AAA C-terminal domain
    2.2e-12   47.5   0.1    6.1e-12   46.1   0.1    1.7  1  AAA              ATPase family associated with various cellul
      2e-09   37.4   0.0    3.6e-09   36.5   0.0    1.4  1  RuvB_N           Holliday junction DNA helicase RuvB P-loop d
    1.8e-05   24.2   0.2      0.019   14.4   0.0    2.4  2  Mg_chelatase     Magnesium chelatase, subunit ChlI
    0.00043   20.3   0.3      0.016   15.2   0.1    2.8  1  AAA_5            AAA domain (dynein-related subfamily)
    0.00092   18.9   0.1      0.061   13.0   0.1    2.4  1  Sigma54_activat  Sigma-54 interaction domain
     0.0012   18.9   0.0     0.0028   17.8   0.0    1.6  1  Sigma54_activ_2  Sigma-54 interaction domain
     0.0021   18.5   0.1       0.54   10.6   0.0    2.8  2  AAA_16           AAA ATPase domain
     0.0052   16.6   0.0      0.054   13.3   0.0    2.4  2  AAA_3            ATPase family associated with various cellul
     0.0098   15.6   0.0       0.02   14.7   0.0    1.5  1  AAA_30           AAA domain
  ------ inclusion threshold ------
      0.015   14.5   0.0      0.027   13.7   0.0    1.3  1  DUF815           Protein of unknown function (DUF815)
      0.019   15.3   0.3      0.039   14.3   0.3    1.6  1  AAA_19           AAA domain
      0.031   14.6   0.0      0.087   13.1   0.0    1.7  1  AAA_22           AAA domain
      0.037   14.0   0.0      0.078   13.0   0.0    1.5  1  TsaE             Threonylcarbamoyl adenosine biosynthesis pro
      0.052   13.6   0.0        0.1   12.6   0.0    1.5  1  AAA_14           AAA domain
      0.054   12.7   0.0      0.093   11.9   0.0    1.4  1  TIP49            TIP49 P-loop domain
       0.21   10.7   0.1       0.51    9.5   0.0    1.6  2  NB-ARC           NB-ARC domain
       0.22   11.2   0.5       0.47   10.1   0.1    1.7  2  AAA_24           AAA domain
       0.29   11.5   1.0       0.56   10.5   1.0    1.5  1  zf-Di19          Drought induced 19 protein (Di19), zinc-bind
       0.31   11.0   2.9          6    6.8   0.0    2.7  3  ResIII           Type III restriction enzyme, res subunit
        2.5    8.5   5.5        6.1    7.3   5.5    1.6  1  MGC-24           Multi-glycosylated core protein 24 (MGC-24),


Domain annotation for each model (and alignments):
>> MgsA_C  MgsA AAA+ ATPase C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  196.4   0.1   3.9e-61   3.2e-58       1     152 [.     370     523 ..     370     527 .. 0.96

  Alignments for each domain:
  == domain 1  score: 196.4 bits;  conditional E-value: 3.9e-61
                 TT-HHHHHHHHHHHHHTT--HHHHHHHHHHHHHHTTGGGSTTHHHHHHHHHHHHHHH-TTTTHHHHHHHHHHHHCS----GG.GHHHHHHHHH----.. CS
      MgsA_C   1 GSdpdAAlyylarmleaGedprfiaRRlviiAseDiGlAdpqalqlavaaaeaveriGlpEariaLaqavvylalapKSnaaykAikkaledvkekk.. 97 
                 GSd+dAAlyylarm+++Gedp +iaRRl+++AseDiGlAd+++l+la+++ +ave++GlpEari+La+a+v +al++KS++ay+++++a ++++e +  
  EEA20238.1 370 GSDADAALYYLARMIQSGEDPLYIARRLIVVASEDIGLADNSMLTLAISTHSAVEKVGLPEARINLAHATVAMALSKKSTRAYRGLNNAFAALSEPGva 468
                 9*********************************************************************************************96544 PP

                 -----GGGST...........T-T---GGG--SS------S-CCG--..------ CS
      MgsA_C  98 slevPlhLrnaptklakklgygkgYkyphdypegvvkqqylpdelkkkkfYepte 152
                 sl++PlhLrnapt+l+k+lgygk+Yky+ +y++g v q+ylp++l+++kf e ++
  EEA20238.1 469 SLPIPLHLRNAPTRLMKELGYGKEYKYNPNYKDGQVVQEYLPESLQERKFLEDND 523
                 889******************************************9999988665 PP

>> AAA_assoc_2  AAA C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.6   0.1   4.1e-25   3.4e-22       7      81 .]     300     369 ..     297     369 .. 0.94
   2 ?   -1.7   0.0       4.7   3.8e+03      36      62 ..     419     451 ..     395     463 .. 0.69

  Alignments for each domain:
  == domain 1  score: 78.6 bits;  conditional E-value: 4.1e-25
                  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXHHHHHHHHHHHHH CS
  AAA_assoc_2   7 leddalealaeladGDaRkaLnlLElaaeaaeakegkieitledleealqrkalryDkagdehYdliSAlhKSiR 81 
                  ++d+ +++la+++dGDaR+aLnlLEla+  ++    +  +t++ l+++l+ k+l yD+agd+hYd+iSA+hKSiR
   EEA20238.1 300 VDDELIRYLATFSDGDARTALNLLELAMGLSN----RPGMTKAVLKKSLT-KTLVYDRAGDQHYDTISAFHKSIR 369
                  799*************************9986....699**********6.5688*******************9 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 4.7
                  XXXX.......XXXXXXXXXXXXXXXXXXXXXX CS
  AAA_assoc_2  36 aaeak......egkieitledleealqrkalry 62 
                  +++a       e +i++ +++++ al++k++r 
   EEA20238.1 419 THSAVekvglpEARINLAHATVAMALSKKSTRA 451
                  333324466667788888888888888887765 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.1   0.1   7.5e-15   6.1e-12       1     125 [.     161     267 ..     161     272 .. 0.89

  Alignments for each domain:
  == domain 1  score: 46.1 bits;  conditional E-value: 7.5e-15
                 EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTS....TSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHH CS
         AAA   1 vllyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakeka....kpsilfiDEidalaksrsgseseeeervvnqLlteldg 95 
                 ++l+G  GtGKT++a+ +a  +g++f+ei+ ++          ++ +++f+ea+++     +++ilf DEi+++ k++           +++Ll  ++ 
  EEA20238.1 161 MILWGGAGTGKTTIARVIACMVGSRFVEINSTTSG-------IAECKKIFAEARNELgltgRKTILFCDEIHRFSKTQ-----------QDVLLGPVES 241
                 79****************************99888.......89999*****99999999878***************...........9999988776 PP

                 TTTSSSTEEEEEEESS..GGGSTHHHHSTTSS CS
         AAA  96 vkkkeskvivigatnr..pdkldpallrgRfd 125
                        v++i+at++    k+++all +R+ 
  EEA20238.1 242 GV-----VTLIAATTEnpSFKVQNALL-SRCR 267
                 64.....68899998877889999999.9986 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.5   0.0   4.5e-12   3.6e-09       1     117 [.     129     248 ..     129     271 .. 0.80

  Alignments for each domain:
  == domain 1  score: 36.5 bits;  conditional E-value: 4.5e-12
      RuvB_N   1 lrPksleeyigqekvkeklkifieaakkreealdhvllyGpPGlGkttlakiiakelg...vklkitsgPvlekagdlaalltnl...eekdvlfidei 93 
                 +rPksl+e +gq+ v  +    i  +   ++ +  ++l G  G Gktt+a++ia  +g   v++++t++ + e ++ +a   ++l    +k +lf dei
  EEA20238.1 129 MRPKSLDEVCGQDLVGPNG---ILRSLIEQDRVPSMILWGGAGTGKTTIARVIACMVGsrfVEINSTTSGIAECKKIFAEARNELgltGRKTILFCDEI 224
                 69**********9998773...333444556677899******************9984345678888888888888887777762225789******* PP

      RuvB_N  94 hrlsraveevlysamedfrldivi 117
                 hr+s++ ++vl   +e   + ++ 
  EEA20238.1 225 HRFSKTQQDVLLGPVESGVVTLIA 248
                 ***********9999988777765 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.3   0.1    0.0034       2.8      24      46 ..     160     182 ..     158     207 .. 0.84
   2 !   14.4   0.0   2.3e-05     0.019     107     143 ..     216     252 ..     209     269 .. 0.81

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0034
  Mg_chelatase  24 nlllvGppGsGKtmlakrlpsll 46 
                   +++l G +G+GKt +a+ ++ ++
    EEA20238.1 160 SMILWGGAGTGKTTIARVIACMV 182
                   589*************9987765 PP

  == domain 2  score: 14.4 bits;  conditional E-value: 2.3e-05
  Mg_chelatase 107 nGvLfLDElpefkrkvlevLRePledgevtisrakak 143
                   + +Lf DE+  f+++  +vL  P+e+g vt+  a+++
    EEA20238.1 216 KTILFCDEIHRFSKTQQDVLLGPVESGVVTLIAATTE 252
                   679**************************98766543 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.1     2e-05     0.016       2     102 ..     161     252 ..     160     287 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 2e-05
                 EEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--.........--------G-SEEEEESGGG--HHHHHHHHHHHHSSEEE..-SS CS
       AAA_5   2 vlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreikngttslvdsplvraaregeilvlDEveraesevlnsLlslleerrllleegg 100
                 ++L G  GtgK+++a+ +a ++++++++++ t +   ++ k         +++ +  l+    ++ il+ DE++r ++  +++Ll + e   + l   +
  EEA20238.1 161 MILWGGAGTGKTTIARVIACMVGSRFVEINSTTS-GIAECKKIFA-----EARNELGLT---GRKTILFCDEIHRFSKTQQDVLLGPVESGVVTLIAAT 250
                 79********************998888876653.3333333333.....333444444...6889999999999999999999999998888777766 PP

                 SE CS
       AAA_5 101 el 102
                 ++
  EEA20238.1 251 TE 252
                 65 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.0   0.1   7.5e-05     0.061      24     130 ..     160     252 ..     148     277 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 7.5e-05
                      -EEEECSTTSSHHHHHHHHHHHSTTTTS-EEEEETTTS-TTCHHHHHHEBSSSSSTTTSS-BEHHHHHTTTSEEEEETGGGS-HHHHHHHHHHH CS
  Sigma54_activat  24 svlitGesGtGKellaraiheaskrkekpfvavncaaipeelleseLFGhekGaFtGAekekkGlfekadgGtlfLDeigelplelQekLlrvl 117
                      s+++ G  GtGK+++ar i        ++fv++n +     + e       k  F  A++e  Gl     + +lf Dei++++ + Q  Ll  +
       EEA20238.1 160 SMILWGGAGTGKTTIARVIACMVG---SRFVEINSTTS--GIAE------CKKIFAEARNE-LGLT--GRKTILFCDEIHRFSKTQQDVLLGPV 239
                      466788999999999999876554...67888887643..3333......35567777653.4764..5789********************** PP

                      HHSEEESBTSSSE CS
  Sigma54_activat 118 qegevervGsske 130
                      ++g v+ + +++e
       EEA20238.1 240 ESGVVTLIAATTE 252
                      9999988876654 PP

>> Sigma54_activ_2  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   3.4e-06    0.0028      24     110 ..     161     253 ..     151     273 .. 0.84

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 3.4e-06
                      EEEEEETT--HHHHHHCC.--TTS-EE--SSTTHHHH-HHHHHHHT........TTSEEEEEE-TT--HHHHHHHHHHHHHHTTTT-EEEEEEE CS
  Sigma54_activ_2  24 vfltGekGsgkelvArlL.hknsgpwleifvverlaklpldlleqa........kggtLylkdiadlskaeqkeLlellakaeksslrlVstss 108
                      + l G++G+gk+++Ar++ +  +++ +ei    +++++ ++++++a        +  +L+  +i+ +sk +q  Ll+ ++++    + l++++ 
       EEA20238.1 161 MILWGGAGTGKTTIARVIaCMVGSRFVEINSTTSGIAECKKIFAEArnelgltgRKTILFCDEIHRFSKTQQDVLLGPVESG---VVTLIAATT 251
                      5678*************945678899*****99999********9877888888999******************9999887...777777776 PP

                      E- CS
  Sigma54_activ_2 109 kd 110
                      ++
       EEA20238.1 252 EN 253
                      65 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.6   0.0   0.00066      0.54      21      45 ..     155     179 ..     146     195 .. 0.80
   2 ?    4.8   0.0     0.042        34     132     155 ..     212     235 ..     188     247 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00066
      AAA_16  21 sgrpelvllsGesGvGKsslvrell 45 
                 ++r ++++l G +G+GK++++r ++
  EEA20238.1 155 QDRVPSMILWGGAGTGKTTIARVIA 179
                 45559***************99775 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.042
      AAA_16 132 rderplvlvlDdlqwadeaslqll 155
                  ++r+++l++D+++++  +++++l
  EEA20238.1 212 LTGRKTILFCDEIHRFSKTQQDVL 235
                 33567**************99995 PP

>> AAA_3  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.3   0.0   6.7e-05     0.054       3      99 ..     162     252 ..     160     264 .. 0.86
   2 ?    0.1   0.0      0.85   6.9e+02       4      24 ..     329     349 ..     327     356 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 6.7e-05
       AAA_3   3 llegvPGlaktllvkalakaldlefkriqftpdllPsdilGtevfeekekefefkkGpvfanllladeinrappktqsalleameerqvtvegethk 99 
                 +l g  G++kt++++ +a +++ +f  i  t+  +      +++f e+++e+ ++     + +l++dei r +   q  ll  +e   vt+  +t++
  EEA20238.1 162 ILWGGAGTGKTTIARVIACMVGSRFVEINSTTSGIA---ECKKIFAEARNELGLTGR---KTILFCDEIHRFSKTQQDVLLGPVESGVVTLIAATTE 252
                 677889***********************9986554...468999999999998753...6899*********99999******9999999887765 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.85
       AAA_3   4 legvPGlaktllvkalakald 24 
                 l + PG++k++l k+l+k+l 
  EEA20238.1 329 LSNRPGMTKAVLKKSLTKTLV 349
                 5688************99875 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   2.4e-05      0.02      21      71 ..     161     215 ..     148     254 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 2.4e-05
      AAA_30  21 avltGpAGtGKttalkalreaweaag....grviglAptgkaAkvLaeelgieas 71 
                 ++l G+AGtGKtt+ ++++ ++ ++      +  g+A  +k  ++ ++elg++++
  EEA20238.1 161 MILWGGAGTGKTTIARVIACMVGSRFveinSTTSGIAECKKIFAEARNELGLTGR 215
                 6899**************9999887435667777888888888888888886444 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   3.3e-05     0.027      48     116 ..     153     224 ..     143     243 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 3.3e-05
      DUF815  48 leglpannvLLwGarGtGKSslvkallneyaeegLrlieve..kedlkelpklvellr....erperfilfvDDL 116
                 +e+ +   ++LwG  GtGK ++ + +   + +   r++e++   + ++e +k++++ r     + ++ ilf+D +
  EEA20238.1 153 IEQDRVPSMILWGGAGTGKTTIARVIACMVGS---RFVEINstTSGIAECKKIFAEARnelgLTGRKTILFCDEI 224
                 566667789************99999877665...5666651156799999999988833324689*******97 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.3   4.8e-05     0.039      11      42 ..     159     189 ..     150     323 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 4.8e-05
      AAA_19  11 kvllvtaGpGtGKTrvlkhivallvelggvkp 42 
                 + +++ +G+GtGKT++ + ++a++v  + v+ 
  EEA20238.1 159 PSMILWGGAGTGKTTIAR-VIACMVGSRFVEI 189
                 5799**********8655.5566665555554 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   0.00011     0.087       7      91 ..     160     233 ..     155     246 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 0.00011
      AAA_22   7 ilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsst..sskdllrellralglelkaerlsseell.ealeqalrarav 91 
                 +++++G +GtGKTt +r ++            ++++v+++ + s+  + k+++ e  ++lgl     ++++  l+ + +++ ++++++
  EEA20238.1 160 SMILWGGAGTGKTTIARVIACMV---------GSRFVEINSTTSGiaECKKIFAEARNELGL-----TGRKTILFcDEIHRFSKTQQD 233
                 6899******************9.........9****9999999999999999999999996.....457788888888888888887 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   9.5e-05     0.078      21      55 ..     160     196 ..     136     204 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 9.5e-05
                 EEEEEESTTSSHHHHHHHHHHHTT--..----TTTTS CS
        TsaE  21 vilLeGdLGaGKTtlvrglakalgve..evkSPTFtl 55 
                  ++L G  G+GKTt++r +a  +g +  e++S T  +
  EEA20238.1 160 SMILWGGAGTGKTTIARVIACMVGSRfvEINSTTSGI 196
                 3899********************99999*9999655 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   0.00012       0.1       6      81 ..     162     232 ..     158     275 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 0.00012
      AAA_14   6 vitGaRrvGKTtllkqlikellvkkesilyinldderdkkladpekllelilek.lkeekktylflDEiqevpewek 81 
                 ++ G   +GKTt+++ ++       +++++in  +   ++ ++   + e+  e+ l++ +kt+lf DEi++ ++ ++
  EEA20238.1 162 ILWGGAGTGKTTIARVIACMVG---SRFVEINSTTSGIAECKKI--FAEARNELgLTG-RKTILFCDEIHRFSKTQQ 232
                 66777789*****998886666...9*******99888877755..566666666777.9**********9976554 PP

>> TIP49  TIP49 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   0.00011     0.093      36      95 ..     146     201 ..     127     287 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00011
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49  36 agvivelikekklaGravLlaGpsgtGktalaiaiskelgedvpfvalsgsevyslevkk 95 
                  g++ +li+++++   +++l G +gtGkt +a  i+  +g    fv ++++    +e kk
  EEA20238.1 146 NGILRSLIEQDRVP--SMILWGGAGTGKTTIARVIACMVG--SRFVEINSTTSGIAECKK 201
                 58999*******98..89999****************999..568888887766666666 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.0   0.00063      0.51       8      41 ..     148     179 ..     145     220 .. 0.87
   2 ?   -3.4   0.0       5.4   4.4e+03      22      43 ..     326     347 ..     323     361 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00063
                 HHHHHHCTTTSCSEEEEEEESTTSSHHHHHHHHC CS
      NB-ARC   8 viekLlekdelqslvvalvGmgGvGKttlakqil 41 
                 +   L e+d +    + l G +G GKtt+a+ i 
  EEA20238.1 148 ILRSLIEQDRVP--SMILWGGAGTGKTTIARVIA 179
                 567788888888..899*************9875 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 5.4
                 EEEEEESTTSSHHHHHHHHCCS CS
      NB-ARC  22 vvalvGmgGvGKttlakqilnk 43 
                  ++l+ ++G+ K +l k+  + 
  EEA20238.1 326 AMGLSNRPGMTKAVLKKSLTKT 347
                 6889999999999999887765 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       5.5   4.5e+03      53      72 ..      11      30 ..       4      33 .. 0.81
   2 ?   10.1   0.1   0.00058      0.47       4      29 ..     160     189 ..     157     202 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 5.5
      AAA_24 53 ldevvelaaeladyktlviD 72
                ++ev+ +a  ++d++  viD
  EEA20238.1 11 VKEVNINAHIDSDCQNFVID 30
                567777799999*******9 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00058
      AAA_24   4 kiliyGpsgiGKTtlakel....gpkplfi 29 
                 +++++G +g+GKTt+a+ +    g +++ i
  EEA20238.1 160 SMILWGGAGTGKTTIARVIacmvGSRFVEI 189
                 689************997766666666665 PP

>> zf-Di19  Drought induced 19 protein (Di19), zinc-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   1.0   0.00069      0.56      32      50 ..       2      21 ..       1      25 [. 0.79

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00069
     zf-Di19 32 vvCPvCaekvtk.dlvaHlt 50
                v CP+Ca++v++ ++ aH+ 
  EEA20238.1  2 VSCPICAKNVKEvNINAHID 21
                67999999998778888986 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.2       4.5   3.7e+03      96     119 ..      36      62 ..       9      89 .. 0.62
   2 ?    3.5   0.1     0.077        62      23      42 ..     157     176 ..     133     182 .. 0.78
   3 ?    6.8   0.0    0.0073         6     122     146 ..     205     229 ..     184     253 .. 0.73

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 4.5
                 -..........-SEEEEEHHHHHHTH. CS
      ResIII  96 a...kekdstnkkilvttiqsldadse 119
                 +   ++++++ + i +++ +s+ ++s+
  EEA20238.1  36 QsdsSSSQKNGTAINFFQPSSARKSSS 62 
                 244456778888888888888888774 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.077
                 TTSEEEEEESTTSTHHHHHH CS
      ResIII  23 rdkrglikmaTGtGKTlvaa 42 
                 r   ++++   GtGKT +a 
  EEA20238.1 157 RVPSMILWGGAGTGKTTIAR 176
                 334788999*******9984 PP

  == domain 3  score: 6.8 bits;  conditional E-value: 0.0073
                 .....HHHTTT-SEEEEETGGGTTS CS
      ResIII 122 eeeseellrdrfdviiiDEaHrlga 146
                 e  +e  l +r+ ++++DE Hr+++
  EEA20238.1 205 EARNELGLTGRKTILFCDEIHRFSK 229
                 3355666778888**********98 PP

>> MGC-24  Multi-glycosylated core protein 24 (MGC-24), sialomucin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   5.5    0.0075       6.1      26     100 ..       7      81 ..       3      88 .. 0.84

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0075
      MGC-24  26 CkgeekskcsenstvedCsvvnvtelcsaaskstpkptnstaktttkpsstttstsvatsgttnttvtptsqpar 100
                 C ++ k ++ +    +dC+++   ++  ++s+s+++++n ta +  +pss+ +s+s++++++t +t++ ++++++
  EEA20238.1   7 CAKNVKEVNINAHIDSDCQNFVIDDSSLSQSDSSSSQKNGTAINFFQPSSARKSSSTVVHASTFSTPSRSNEVSK 81 
                 6666666666666679***************************************99988888888877776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (534 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       852  (0.0475208); expected 358.6 (0.02)
Passed bias filter:                      680  (0.0379274); expected 358.6 (0.02)
Passed Vit filter:                       108  (0.00602376); expected 17.9 (0.001)
Passed Fwd filter:                        22  (0.00122706); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              22  [number of targets reported over threshold]
# CPU time: 0.69u 0.28s 00:00:00.97 Elapsed: 00:00:00.44
# Mc/sec: 3671.32
//
Query:       EEA20239.1  [L=541]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
       0.19   11.9  12.5       0.35   11.0  12.5    1.4  1  Zn_clus    Fungal Zn(2)-Cys(6) binuclear cluster domain
       0.19   11.5   7.6       0.49   10.2   7.6    1.7  1  zf-RING_4  RING/Ubox like zinc-binding domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0  12.5   3.9e-05      0.35       2      30 ..     129     159 ..     128     161 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 3.9e-05
                 S-HHHHHCT---STSSSS-HHHHHCT...HHH CS
     Zn_clus   2 aCdnCrkkKvKCdakkPaCsnCkkln...leC 30 
                 +C+ C k++ +C+ + P C nC++++    +C
  EEA20239.1 129 SCIWCYKRRKQCNSEVP-CPNCRRNErdeNDC 159
                 8****************.******98666666 PP

>> zf-RING_4  RING/Ubox like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   7.6   5.5e-05      0.49      25      45 ..     130     151 ..     128     152 .. 0.92

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 5.5e-05
   zf-RING_4  25 ClfCyhrile.eeegrCPaCre 45 
                 C +Cy+r ++ ++e  CP+Cr+
  EEA20239.1 130 CIWCYKRRKQcNSEVPCPNCRR 151
                 ********998899*******8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (541 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       483  (0.0269396); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.42
# Mc/sec: 3836.99
//
Query:       EEA20240.1  [L=431]
Description: kynurenine aminotransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.1e-71  240.1   0.0    4.7e-71  239.9   0.0    1.0  1  Aminotran_1_2    Aminotransferase class I and II
    0.00014   20.5   0.0    0.00025   19.7   0.0    1.4  1  Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
     0.0045   16.3   0.0     0.0067   15.7   0.0    1.2  1  Beta_elim_lyase  Beta-eliminating lyase
  ------ inclusion threshold ------
      0.022   13.7   0.0      0.047   12.6   0.0    1.5  1  Aminotran_5      Aminotransferase class-V
      0.057   12.7   0.0       0.23   10.7   0.0    1.8  1  DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family


Domain annotation for each model (and alignments):
>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  239.9   0.0   1.3e-74   4.7e-71       2     363 .]      39     420 ..      38     420 .. 0.95

  Alignments for each domain:
  == domain 1  score: 239.9 bits;  conditional E-value: 1.3e-74
                    EEEESSSSSTTSTTSSHHHHHHHHHHHHHHHHHTSTTST-BTTHHHHHHHHHHHHHCTCTTCHTTGGEGEEEESHHHHHHHHHHHHHHHTTT-EEE CS
  Aminotran_1_2   2 dvinLgsneylgdsgkptlpevakaekegalaggtlneygpidglpeleealakflgrseklklkreaavvvgsGagaliealifllklnpgdeil 97 
                    +++n+g++ + +     +++ ++ a+ke al++ ++n+y+p++g p l++a+a  +++s + +l++e++v+ ++Ga+++   +++++ ++pgde++
     EEA20240.1  39 PIVNMGQGFFGYN----PPKFALDAAKE-ALDKVDCNQYSPTKGRPHLKKAIAATYSKSFGRELDPETEVTITTGANEGMLSAFMAF-IEPGDEVI 128
                    579**********....***********.**********************************************************.******** PP

                    EEESS-THHHHHHHHTTSEEEEEEBEET..........TTTEE-HHHHHHHHTTHHCTTETEEEEEEESS-TTT--B--HHHHHHHHHHHHHTTEE CS
  Aminotran_1_2  98 vpdptyasyknilrlsggevvryplyse..........edfhldlealeealkeapegnkktkvilvesphNPtGtvatleeleklldlakkynll 183
                    +++p++++y+ ++++ gg+++++pl ++           ++++d+e+le+ ++       kt++i+++sphNP G+v+t+eel+ + dla k+n++
     EEA20240.1 129 IFEPFFDQYISNIEMPGGTIRYVPLLPPkdgairtssaSEWTIDFEQLEKTINP------KTRMIVLNSPHNPVGKVMTREELTRIGDLAVKHNII 218
                    ***************************9*************************9......************************************ PP

                    EEEEETTTTCBSSSSHTHHHHGGSTTSTT..EEEEEESSSTTSSGGG-EEEEEEEHHHHHHHHHHHHHHTS..SHHHHHHHHHHHHHHHHHHHHHH CS
  Aminotran_1_2 184 lfvDeaYagfvfgsldavatranveeepn..llivgslsKafGlaGeRvGyilgnaavvsqlrklsrpfls..ssllqaavaaalsdallkqsele 275
                    +++De+Y  +++ +  +++ +a++++e    +++vgs +Kaf ++G+RvGy++g ++++++++ +++++++   s+lq+a a a ++a+ +  + e
     EEA20240.1 219 ILSDEVYDRLYYVP--FTR-IATLSPELYerTITVGSAGKAFYATGWRVGYLIGPPHLIKYVAAAHTRICYssVSPLQEASAVAFEKADAEG-FWE 310
                    ************94..555.********9******************************************777889999999999988654.*** PP

                    HHHHHHHHHHHHHHHHHHHSTEEEECCSCSSEEEEEETHH................CHHHHHHHHHHTCTEEEEEGGGGTS.......TTEEEEEC CS
  Aminotran_1_2 276 emrqrlqkrrkelrdeLaelglkvlasqsgmflltdlsae................takelskkLleevgvyvtpgtsftv.......pgrlRitv 348
                    e+r ++q + +++++ ++el++++ ++++g+f+l  +                   ++ +l+  L++evgv+ +p t+f++       +  lR+ v
     EEA20240.1 311 ESRNEMQGKIRRFCEVFDELDIPYSDPEGGYFVLANMASVklpsdypfpphvasrpRDFKLAWFLIKEVGVAAIPPTEFYTdanahiaEDYLRFAV 406
                    **************************************99888888888887775555555555******************************** PP

                    TTS-HHHHHHHHHHH CS
  Aminotran_1_2 349 Aglteeeleelveal 363
                     +  ++ le + e+l
     EEA20240.1 407 -CKEDDVLETAKERL 420
                    .88888888887775 PP

>> Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.0     7e-08   0.00025      81     175 ..     114     224 ..      95     231 .. 0.75

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 7e-08
                      HHHHHTTS-TTEE..........EEEESTSSHHHHHHHHHTHHH.TTCEEEEEST..TSHHHHHHHCCTTEEEEEEESS-TTTT---...-HHH CS
  Cys_Met_Meta_PP  81 aaailallkaGde..........ivvsddlYggtqrllkkvlkk.lgievkfvdt..sdleelekaikentklvylEtptnpllkvv...Diek 158
                       +a++a+++ Gde           +++ ++ ggt r++  + +k   i+++       d+e+lek i+++t+++ l +p np+ kv+    +++
       EEA20240.1 114 LSAFMAFIEPGDEviifepffdqYISNIEMPGGTIRYVPLLPPKdGAIRTSSASEwtIDFEQLEKTINPKTRMIVLNSPHNPVGKVMtreELTR 207
                      467788888888844444444445555556689999999999984456665555333799**********************999974447889 PP

                      HHHHHHHTT-EEEEEGT CS
  Cys_Met_Meta_PP 159 iaklakkagvlvvvDnt 175
                      i +la k++++++ D +
       EEA20240.1 208 IGDLAVKHNIIILSDEV 224
                      999999**999998876 PP

>> Beta_elim_lyase  Beta-eliminating lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   1.9e-06    0.0067      63     167 ..     116     222 ..      68     223 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 1.9e-06
                      HHHHH--TTEEEEEETT......-HHHHSST..THHHHC..C--EEEEE-EBTTTBE-HHHHHHHS--S-TTS-EEEEEEEESSBTTTTTB--- CS
  Beta_elim_lyase  63 llkillqrgeevivtep......ahihfdet..gaiael..agvklrdlknkeaGkmdlekleaaikevgaheekiklisltvTnntagGqvvs 146
                      ++++++++g+evi+ ep      ++i++     + +  l  ++   r+   +e  ++d+e+le+ i++      k+++i+l   +n   G+v++
       EEA20240.1 116 AFMAFIEPGDEVIIFEPffdqyiSNIEMPGGtiRYVPLLppKDGAIRTSSASE-WTIDFEQLEKTINP------KTRMIVLNSPHNP-VGKVMT 201
                      45777777777777777555555555543221244444443333344444444.89999999999999......699*********5.9***** PP

                      HHHHHHHHHHHHHCT-EEEEE CS
  Beta_elim_lyase 147 leelrevaaiakkygiplhlD 167
                       eel ++ ++a k++i ++ D
       EEA20240.1 202 REELTRIGDLAVKHNIIILSD 222
                      ***************988877 PP

>> Aminotran_5  Aminotransferase class-V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   1.3e-05     0.047     123     177 ..     167     224 ..      96     226 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.3e-05
                  TTSCBEGGGHHHH--TTEEEEEEESBETTTTEB...--HHHHHHHHHHTT-EEEEE-T CS
  Aminotran_5 123 eegeldldelekllnektklvaithvsnvtGti...qpveeigklakkkgalvlvDaa 177
                  +e+++d ++lek++n+kt+++ ++   n  G +   +++ +ig+la k+++++l D +
   EEA20240.1 167 SEWTIDFEQLEKTINPKTRMIVLNSPHNPVGKVmtrEELTRIGDLAVKHNIIILSDEV 224
                  6899***************************751226788899999999**9999965 PP

>> DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   6.4e-05      0.23      94     144 ..     166     222 ..      86     223 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 6.4e-05
                      TTTSSB-GGGCGGG--TTEEEEE...EB-GGGB--...-HHHHHHHHHHCT-EEEEE CS
  DegT_DnrJ_EryC1  94 pdtynidpaaieaaitertkaIl...pVhlyGqva...dmdalkaiaakhglkvieD 144
                      +  ++id +++e+ i+++t+ I+   p + +G+v+   ++ ++ ++a kh++++++D
       EEA20240.1 166 ASEWTIDFEQLEKTINPKTRMIVlnsPHNPVGKVMtreELTRIGDLAVKHNIIILSD 222
                      4679******************944445678988766789999999********998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (431 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       257  (0.0143343); expected 358.6 (0.02)
Passed bias filter:                      254  (0.014167); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.40
# Mc/sec: 3257.48
//
Query:       EEA20241.1  [L=1201]
Description: C2 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    7.1e-29  100.1   0.0      3e-16   59.6   0.0    2.6  2  C2           C2 domain


Domain annotation for each model (and alignments):
>> C2  C2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.6   0.0   1.7e-20     3e-16       3      94 ..     489     589 ..     487     598 .. 0.90
   2 !   38.0   0.0   8.7e-14   1.6e-09       3     103 .]     677     804 ..     675     804 .. 0.80

  Alignments for each domain:
  == domain 1  score: 59.6 bits;  conditional E-value: 1.7e-20
                 EEEEEEEEESSSSSSTTSS....CEEEEEEEE..ECEEEEEE-SCSSSSSSEEEEEEEEEESC...HTTSEEEEEEEEECSSSTEEEEEEEEEEGHHHH CS
          C2   3 levtvieAknLpnkdkkgs....sdpyvkvsl..dgkqkakTrviknslnPvWnekftfevae...leeakLeveVfdndrlskddfiGkveiplstll 92 
                 + +++++A +L ++d  gs    sdpy+ +s+   gk +++Trvi + lnPvW+e+  + v++   +++++L +e++d+dr s dd++Gk+e+++++l 
  EEA20241.1 489 FWIRIHRAIGLSKQDRRGSdgggSDPYINLSFskYGKPMYCTRVITDDLNPVWEETAALLVTPeliKADEQLSIELWDSDRNSADDIVGKMELSIQELI 587
                 5689*******999995555555*********999**************************999********************************955 PP

                 TT CS
          C2  93 sg 94 
                 ++
  EEA20241.1 588 QH 589
                 44 PP

  == domain 2  score: 38.0 bits;  conditional E-value: 8.7e-14
                 EEEEEEEEESSSSSSTTSS..........................CEEEEEEEEECEEEEEE-SCSSSSSSEEE...EEEEEEESCHTTSEEEEEEEEE CS
          C2   3 levtvieAknLpnkdkkgs..........................sdpyvkvsldgkqkakTrviknslnPvWn...ekftfevaeleeakLeveVfdn 72 
                  ++ v++  nL+  d+ gs                          + +y+++ l+++ +++Tr +  s +P++n   e+f+ ++    +a ++v+V d+
  EEA20241.1 677 CSIVVHQIVNLQLEDIYGSqgnrkgrefepakaygenteeqgedlPTSYCTILLNDQLVYRTRAKAVSSKPIFNagtERFVRDW---RSALVTVTVRDQ 772
                 678899999999998844444456667777777777778888888******************8855559***95445555555...55*********9 PP

                 CSSSTEEEEEEEEEEGHH.HHTTHHHHEEEEH CS
          C2  73 drlskddfiGkveiplst.llsgeeaegwypl 103
                 ++ ++d ++G+v+++ls+ ++++++ ++wypl
  EEA20241.1 773 RHREHDPILGVVSLRLSDlMQTSSQVTRWYPL 804
                 9977777***********999999******97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1201 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1164  (0.0649228); expected 358.6 (0.02)
Passed bias filter:                      612  (0.0341346); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.97u 0.32s 00:00:01.29 Elapsed: 00:00:00.51
# Mc/sec: 7100.35
//
Query:       EEA20242.1  [L=294]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-17   64.1   3.3    9.4e-17   61.6   0.5    2.6  2  GET2      GET complex subunit GET2


Domain annotation for each model (and alignments):
>> GET2  GET complex subunit GET2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.6   0.5   5.2e-21   9.4e-17       8     244 ..      13     252 ..       7     261 .. 0.63
   2 ?    1.1   0.1     0.014   2.5e+02     289     308 ..     262     281 ..     255     282 .. 0.90

  Alignments for each domain:
  == domain 1  score: 61.6 bits;  conditional E-value: 5.2e-21
        GET2   8 rrlLRERRqaKmakGgAssRLnkItgqgssvksst..tsvLd......epaaekttpasttasssssas........ehddpeiediseiavkpkktas 90 
                 +rl+RERR+aK+++G +s+RL kIt+   +   s    s         +p+a+++ p++t+ +++s +               + d+++i  +++   +
  EEA20242.1  13 ARLRRERREAKIKAG-GSARLDKITSLSGRTPASMqdVS--PspppqpHPQATPNLPTQTQPTQTSPQPtippagtaP-----EADPETIRAQQEYLRA 103
                 6**************.***********988877773333..2457766566666666666666655555676544433.....3344444444544545 PP

        GET2  91 skkksplseesepeapqldqllkqllqq..qqqgnsensqdaesstPdlfsqllkmmkqgeggsakseeetssspeeaeyqqqlleyhkyqvkklkarf 187
                 + +++p +++  +++ + d ++k l ++   + g ++++ +a++++P+  +  l   + ++   a + ++  s++      +q+   +k + k lk+++
  EEA20242.1 104 LLRANPPEQQ-AQQQIDQDPMMKVLSSMlgGMPGAENTAPGAGMAPPNQGN--LGTNDLTS---ALGIPPLLSNMIFGGGASQQTPEEKNRDKILKLLH 196
                 5555555444.3333344445555555521244555555555555555555..33322222...234566666666666666666667789999***** PP

        GET2 188 llvrllllllnfvYhvfrssksalvralteas.vrnFftvFltfEvvllsiyylllkk 244
                 +l++l++++  ++ ++++s  +++     ++  ++n f +F+t+E++l++++++l k+
  EEA20242.1 197 TLFALFVGV--YLVTLLSSAVTTYGANPPPPAtAQNPFVIFMTVELLLIGARMVLGKT 252
                 ***999999..444445555557777777776899******************99844 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.014
        GET2 289 evlsmlltDlslvvvlfGll 308
                 +++ +l+ D s+v++++G++
  EEA20242.1 262 QIFRTLVRDGSIVIFALGVA 281
                 7999**************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (294 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       784  (0.043728); expected 358.6 (0.02)
Passed bias filter:                      460  (0.0256568); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.41
# Mc/sec: 2142.64
//
Query:       EEA20243.1  [L=668]
Description: acetyl-coenzyme A synthetase FacA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.4e-88  295.7   0.1    5.3e-88  295.4   0.1    1.1  1  AMP-binding    AMP-binding enzyme
    1.7e-27   96.2   0.2    9.4e-26   90.6   0.2    2.7  2  AMP-binding_C  AMP-binding enzyme C-terminal domain
    1.3e-16   60.3   0.1    3.4e-16   58.9   0.1    1.8  1  ACAS_N         Acetyl-coenzyme A synthetase N-terminus


Domain annotation for each model (and alignments):
>> AMP-binding  AMP-binding enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  295.4   0.1   8.9e-92   5.3e-88       2     422 ..     102     540 ..     101     541 .. 0.87

  Alignments for each domain:
  == domain 1  score: 295.4 bits;  conditional E-value: 8.9e-92
                  HHHHHHSTTSEEEEE....CCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTE CS
  AMP-binding   2 eeqaaktpdkvalvd....sgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledsea 95 
                  +++a k+pdkva+++      eg+++TY+el ++v+r+A +L+s Gv+kgd+Vai+lp+ pe +va+la++++Gav++++ ++++++ l+  + d+++
   EEA20243.1 102 DRHAIKNPDKVAIIYeadePSEGRSITYGELLREVSRVAWVLKSQGVRKGDTVAIYLPMIPEALVAFLACARIGAVHSVVFAGFSSDSLRDRVLDANS 199
                  678889*************899*********************99***************************************************** PP

                  SEEE.........E..TCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS...-TSCCCS-BTTSEEEEEEE--SSSS-EEEEE CS
  AMP-binding  96 kvli.........a..tvdselleklleaaakleavklvivldadellkeeelkeeeeseekae...kpeeeeelkpddlayiiYTSGTTGkPKGVml 179
                  k++i         +   +     + ++ea ++ ++v+ v+v ++ +++  ++   +  + e+ e   +   +e+++++d+++++YTSG+TGkPKGVm+
   EEA20243.1 200 KFVItadegkrggKiiGT----KKIVDEALKQCPDVTNVLVFKRTGADVPWTKGRDLWWHEEVEkypNYIAPETVDSEDPLFLLYTSGSTGKPKGVMH 293
                  ****99988755423322....34466777777888999999988776665555444444333256745567789*********************** PP

                  EH.HHHHHHHHHHHHHHC.SCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGC.CHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHH CS
  AMP-binding 180 sh.rnlvanvaslkletr.fklkeddvvlsilplahifglilelllallsGatvvllpkdaa.ldpklllelieklkvtviagvPrvleallesgalk 274
                  ++ ++l+ ++ +   + + f++++dd++++  ++ +i+g+++ ++++ll G + v+++ ++a ++  + +++iek+kvt ++++P++l+ l ++g++ 
   EEA20243.1 294 TTaGYLLGAAMTG--K-YvFDIHDDDRYFCGGDVGWITGHTYVVYAPLLLGVATVVFESTPAyPNFSRYWDVIEKHKVTQFYVAPTALRLLKRAGDEH 388
                  **56666665553..3.4588999**************************************77788889*********************8877666 PP

                  CHHHHCCGTT-SEEEEESS-EBHHHHHHHHHHHTC...EEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBEE.TTSEEEEE CS
  AMP-binding 275 aakkakdlsslrlvllggeplspellrffralfge...evlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeetgepvp.dgeeGell 368
                      ++++ +lr++ ++gep+ +e+++++ + +g+   +++++Y++TEt+  ++++      +k+gs+  p+ g+e +i+D+  g ++  +++eG l 
   EEA20243.1 389 ---IHHKMEHLRVLGSVGEPIAAEVWKWYFESVGKeeaHIVDTYWQTETGSNIITPLGGVTPTKPGSASLPFFGIEPAIIDPVSGAEITgNDVEGVLA 483
                  ...2357899********************999999*99**************886666666899*****************999888537888**** PP

                  EEET..TS-SEBTT-HHHHHHHEEET.CCEEEEEEEEEEETTSEEEEEEECCCEEEE CS
  AMP-binding 369 vrgp..gvmkgYlkkpeataeafdse.grwlrTGDlgrldedGyleivgRkkdlikl 422
                  +++p  ++++  ++ +++  +++ +  ++++ TGD + +d++Gy++i gR +d++++
   EEA20243.1 484 IKQPwpSMARTVWGAHKRYMDTYLNVyKGYYFTGDGAGRDHEGYYWIRGRVDDVVNV 540
                  ***9778****************952567**************************98 PP

>> AMP-binding_C  AMP-binding enzyme C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0      0.05     3e+02       2      18 ..     221     237 ..     221     249 .. 0.85
   2 !   90.6   0.2   1.6e-29   9.4e-26       1      76 []     549     627 ..     549     627 .. 0.94

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.05
                    HHHHHHSSTTEEEEEEE CS
  AMP-binding_C   2 vEsalvshpaVaeaaVv 18 
                    v +al ++p+V ++ V+
     EEA20243.1 221 VDEALKQCPDVTNVLVF 237
                    679************99 PP

  == domain 2  score: 90.6 bits;  conditional E-value: 1.6e-29
                    HHHHHHHSSTTEEEEEEE-----TTS---EEEEEE---..-.--HHHHHHHHHHHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   1 evEsalvshpaVaeaaVvGvpdevkGealvafVvlkdg..s.ealeeeLkahvrkelgpyavpkkvvfvdelpktrsGK 76 
                    e+E+al++hp VaeaaVvGv de++G+a+ afV lk+g  s e+++++L+ +vrk +gp+a+pk+++ vd+lpktrsGK
     EEA20243.1 549 EIEAALLEHPMVAEAAVVGVADELTGQAVNAFVSLKSGneStEQVRKDLIMQVRKSIGPFAAPKQIIPVDDLPKTRSGK 627
                    8**********************************988542344**********************************9 PP

>> ACAS_N  Acetyl-coenzyme A synthetase N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.9   0.1   5.6e-20   3.4e-16       1      55 []      44     100 ..      44     100 .. 0.98

  Alignments for each domain:
  == domain 1  score: 58.9 bits;  conditional E-value: 5.6e-20
                 HHHHHHHHHH-HHHHHHHHHCC.S--SB--S-SECSTTTC.T-EESTT-EE-HHHHH CS
      ACAS_N   1 ykelykeSiedpeaFWaeqake.ldWekpfdkvldgskgp.fikWFeGGklNicyNc 55 
                 yk+ly+eSi++p+ FWa++a+e l++ek+f+++  gs++  + +WF GGklN+++Nc
  EEA20243.1  44 YKKLYEESIRQPDVFWARMARElLTFEKDFHTTHVGSFEHgDNAWFLGGKLNASFNC 100
                 9************************************9999**************** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (668 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       450  (0.025099); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 4507.89
//
Query:       EEA20244.1  [L=1952]
Description: nucleoporin SONB, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.5e-81  272.5   0.6    5.3e-81  271.9   0.6    1.3  1  Nup96           Nuclear protein 96
    2.2e-51  173.9   0.0    3.4e-51  173.3   0.0    1.3  1  Nucleoporin2    Nucleoporin autopeptidase
    3.2e-10   40.7  81.9    1.3e-07   32.4  39.9   10.3  9  Nucleoporin_FG  Nucleoporin FG repeat region


Domain annotation for each model (and alignments):
>> Nup96  Nuclear protein 96
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  271.9   0.6   8.8e-85   5.3e-81       3     292 .]    1471    1783 ..    1469    1783 .. 0.94

  Alignments for each domain:
  == domain 1  score: 271.9 bits;  conditional E-value: 8.8e-85
       Nup96    3 ifalLsghqveeAcelAldagdlrLAtllsqaggddevrkdlqeQleeWreekvdseieeellkiyelLaGnvlvsegkk.kke....stinvle.. 92  
                  ++a+L++h+ve+Ac++++d+gdl+LAt+l+q+g+d+ +r+ +q+Q+e+Wr+++v+se++e+++++yelLaGn l+s g++ ++     st++++e  
  EEA20244.1 1471 AIAYLTQHRVEDACKILVDSGDLHLATMLAQIGRDSVIRSNMQKQVESWRQHNVYSEFSEPIRALYELLAGNALRSIGRSsGALedraSTFTLSErf 1567
                  799**************************************************************************999555499*9********* PP

       Nup96   93 gldWkralglhlwYgisadasieeaveaYeealesgeetakPlpwyleetskesskdakeekrerDllyhLLkly.........akktaslesvleP 180 
                  +ldW++a+gl+lwY i++d+++e av+++ e++++g+e+a P+p +le++ +  +++a+++  e ++l+ +Lk+y         ++ +++l ++++P
  EEA20244.1 1568 ELDWIQAFGLRLWYSITEDEPLEVAVARFFEDITTGDEPAFPFPAHLEQELAGLHQNANSRFLE-SPLWVILKVYaattstnvaSDLKVNLPDAISP 1663
                  *************************************************999988888877766.**********777777665555********** PP

       Nup96  181 esvspspldyrlsWhLyqvLs..aasaeaeklssakadaltlsfasqLeaaglwewAvfVllhledparRekavkellarhasl......eeesdda 269 
                  e+vs + l+ rls++L+q+L    ++ +  ++++a++d+lt+s+as+L+a++++e A+fVllhl+++ +Re+a+ke+l ++a++      ++ ++d+
  EEA20244.1 1664 EAVSGNRLSGRLSFQLHQALVtiVGQNDRVAIDKARTDQLTWSYASELVASNAMEPALFVLLHLSRAGDREHAIKETLGQFAASlptplsQDGKPDD 1760
                  *********************7656778888999999*****************************************************9999*** PP

       Nup96  270 keeflveklkiPeaWiheAkAly 292 
                   +++lv+ l++Pe+Wi+ Ak ly
  EEA20244.1 1761 VWNYLVQALQLPESWIWVAKGLY 1783
                  ********************886 PP

>> Nucleoporin2  Nucleoporin autopeptidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  173.3   0.0   5.7e-55   3.4e-51       2     149 .]     895    1041 ..     894    1041 .. 0.98

  Alignments for each domain:
  == domain 1  score: 173.3 bits;  conditional E-value: 5.7e-55
                    TTEEEES-HHHHHTS-HHHHTSBSS-EEEETTTEEEEESS-B--GGG-HHHHBTTTEEEETTEEEESSSCCC.---TTSTT-S-EEEEESS---B CS
  Nucleoporin2    2 gdYytePsleeLkkmseeelsavkdFtvgrkgvGsveFlepvdlssldldeiagkivklekkevtVYpdeekekppvGegLNkpaeitLenvwpk 96  
                    g+Y+++Ps +eL+kms+++l++v++Ftvgr+++G+v+F++pvd++++dld+++g+iv+++ +++tVYpde++ kpp+G+gLN+p+++ +en+wp+
    EEA20244.1  895 GEYWMKPSRAELSKMSRDQLKHVEGFTVGRQKCGQVTFDRPVDITTIDLDNVLGGIVQITVRSITVYPDEAT-KPPRGKGLNVPSTLRIENSWPR 988 
                    79********************************************************************55.********************** PP

                    -TTT--B---TT-HHHHHHHHHHHH-SSSEEEEEETTTTEEEEEES--XXXXX CS
  Nucleoporin2   97 dkatkeeikdkskarvkkhieklkkvegteFvsydpetgtwtfkVeHFsrYgl 149 
                     +++k++++  s++ ++kh+++l+kv++teFv+y+++tg+w+f+V HF++Ygl
    EEA20244.1  989 GRDRKTSSSIISGPLFDKHVDRLSKVTNTEFVTYEKDTGIWVFRVAHFTTYGL 1041
                    ***************************************************97 PP

>> Nucleoporin_FG  Nucleoporin FG repeat region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7  42.5      0.94   5.6e+03       2      91 .]      11      82 ..       3      86 .. 0.54
   2 ?  -11.1  67.8         3   1.8e+04       1      90 [.      68     165 ..      42     172 .. 0.56
   3 ?   -8.8  37.2         3   1.8e+04       1      78 [.     115     187 ..     115     214 .. 0.61
   4 ?   -5.0  71.9         3   1.8e+04       2      91 .]     286     387 ..     237     391 .. 0.87
   5 !   15.2  43.1   4.7e-06     0.028       1      91 []     358     444 ..     356     444 .. 0.82
   6 !   13.3  37.8     2e-05      0.12       2      80 ..     391     462 ..     388     463 .. 0.83
   7 !   32.4  39.9   2.2e-11   1.3e-07       1      91 []     441     526 ..     441     526 .. 0.90
   8 !   24.4  34.0   6.5e-09   3.9e-05       4      84 ..     530     609 ..     527     619 .. 0.84
   9 ?   -2.3   3.1       1.4   8.2e+03      11      30 ..     707     726 ..     685     764 .. 0.54

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.94
  Nucleoporin_FG  2 lFGaaatstsgglFGststtatstgglFGasstatatasggglfgatsqtaasgglFGstnattqttatgglFGstaataqqttsgglFG 91
                    +FG ++t+++++ FG++    + t+g FG         s++++fga ++t ++g++FGs+++   +  +gg FGs+++++     ++lFG
      EEA20244.1 11 TFG-QNTQQQSSGFGGSGFGGSGTTGGFG---------SNTTAFGA-ANTGTGGSVFGSNTSGGFG--SGGAFGSNQTQT-----NSLFG 82
                    455.5555566666666665556666666.........33334555.5666666666666666555..566666444433.....44554 PP

  == domain 2  score: -11.1 bits;  conditional E-value: 3
  Nucleoporin_FG   1 glFGaaatstsgglFGststt.....atstgglFGasstatatasgg..glfgatsqtaasgglFGstnattqtta...tgglFGstaataqq.. 83 
                     g+FG ++++++++lFG+++ +     at++g+lFG s+tat+t+sg   g fg  s+ + ++g+FGs++a++++      ++ FG+t++t ++  
      EEA20244.1  68 GAFG-SNQTQTNSLFGGNKPSgfgstATTGGSLFG-SNTATTTSSGFgsGGFG--STGTGTTGAFGSNTAANANPFgakPASGFGTTTTTPSTgf 158
                     3566.666666666666666666666666666666.22222222222123333..3666666666666666665555555555666666555555 PP

  Nucleoporin_FG  84 ttsgglF 90 
                       +gg F
      EEA20244.1 159 GGTGGGF 165
                     5555555 PP

  == domain 3  score: -8.8 bits;  conditional E-value: 3
  Nucleoporin_FG   1 glFGaaatstsgglFGststt.....atstgglFGasstatatasggglfgatsqtaasgglFGstnattqtta..tgglFGsta 78 
                     g+FG ++ + ++g+FGs++++      ++ ++ FG   t+t+t+s+g  fg+      +gg FG+t+a + +     g  F +++
      EEA20244.1 115 GGFG-STGTGTTGAFGSNTAAnanpfGAKPASGFG---TTTTTPSTG--FGG------TGGGFGQTTAPAFGGGagAGTAFAGQT 187
                     5799.999999999999999967666666667777...444444444..555......344444444444433333223333333 PP

  == domain 4  score: -5.0 bits;  conditional E-value: 3
  Nucleoporin_FG   2 lFGaaatstsgglFGststt......atstgglFGasstatatasggglfgatsqtaasgglFGstnattqtta...tgglFGstaataqq.... 83 
                     +FG a+t+t++g FG+++t+      ++++++lFG  +++tat++ + lfg+   t+a++g FG++n+t+++++   +++lFG++++++++    
      EEA20244.1 286 AFG-AQTQTTTGGFGTNTTQtnslfgQKPATSLFG--GNTTATTQPS-LFGG---TTATTGGFGAANTTNTPSTgfgGSSLFGNQQQQQKPglfg 373
                     699.999999999999999999999999999****..6666777776.****...7999**************9**999****877776556666 PP

  Nucleoporin_FG  84 ......ttsgglFG 91 
                           tt++g FG
      EEA20244.1 374 sqtpatTTTTGGFG 387
                     66666555555555 PP

  == domain 5  score: 15.2 bits;  conditional E-value: 4.7e-06
  Nucleoporin_FG   1 glFGaaatstsgglFGststtatstgglFG...asstatatasggglfgatsqtaasgglFGstnattqttatgglFGstaataqqttsgglFG 91 
                     +lFG+++++++ glFGs++ ++t+t+g FG     +t+t+++s+++ fg+    +++++ FG++++t +t+a gg FG++a+++   ++ glFG
      EEA20244.1 358 SLFGNQQQQQKPGLFGSQTPATTTTTGGFGstpGFGTNTNATSTTTPFGS----SNTTTGFGNAQQTGTTSAFGGGFGQQAQNQ---AKPGLFG 444
                     69**99999************99999999976533444444444468998....678889********99999999**777765...999***9 PP

  == domain 6  score: 13.3 bits;  conditional E-value: 2e-05
  Nucleoporin_FG   2 lFG.aaatstsgglFGststtatstgglFGasstatatasggglfgatsqtaasgglFGstnattqttatgglFGstaat 80 
                     +FG ++++++++ +FGs++tt     + FG+++++ +t++ gg fg+++q++a+ glFG+t++++    ++glFG++ +t
      EEA20244.1 391 GFGtNTNATSTTTPFGSSNTT-----TGFGNAQQTGTTSAFGGGFGQQAQNQAKPGLFGNTQQQQG---GTGLFGGSGTT 462
                     589777888888999999999.....78**77777777777789****************998765...799***98775 PP

  == domain 7  score: 32.4 bits;  conditional E-value: 2.2e-11
  Nucleoporin_FG   1 glFG.aaatstsgglFGststtatstgglFGasstatatasggglfgat.sqtaasgglFGstnattqttatgglFGstaataqqttsgglFG 91 
                     glFG +++++ ++glFG++ tt   +++lFG  +t++++++g++lfg+   q++ ++glFG++++++++  + +lFG+  +++++tt+++ FG
      EEA20244.1 441 GLFGnTQQQQGGTGLFGGSGTT---GTSLFG--NTQQQQPQGTSLFGGGqPQQTGGTGLFGGAQQQQEQ--KPSLFGGLGTNTTTTTGTSAFG 526
                     79**878888889*********...******..77777777888**9987888899********99987..8***********99*******9 PP

  == domain 8  score: 24.4 bits;  conditional E-value: 6.5e-09
  Nucleoporin_FG   4 G.aaatstsgglFGststtatstgglFGasstatatasggglfgatsqtaasgglFGstnattqtta.tgglFGstaataqq....t 84 
                     G + a++ +++lFGs++++++++ +lFG       ++ g++lfg++++++++g+lFG+++++++t+  ++++F ++++++qq    +
      EEA20244.1 530 GnQPAQTGTTSLFGSNQAQQQQKPSLFG-------NTGGTSLFGGSATAQPTGSLFGGQTQQQPTAGfGTSMFSTSQQNQQQlpaqQ 609
                     5445677788******************.......555558*******************9999988**********9999987531 PP

  == domain 9  score: -2.3 bits;  conditional E-value: 1.4
  Nucleoporin_FG  11 sgglFGststtatstgglFG 30 
                     +g+l Gsts    + +g FG
      EEA20244.1 707 NGSLLGSTSLRGGNVNGSFG 726
                     22333333333333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1952 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       497  (0.0277205); expected 358.6 (0.02)
Passed bias filter:                      297  (0.0165653); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 1.03u 0.32s 00:00:01.35 Elapsed: 00:00:00.49
# Mc/sec: 11861.80
//
Query:       EEA20245.1  [L=557]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.2e-49  166.4  23.8    8.2e-49  166.4  23.8    2.0  2  MFS_1     Major Facilitator Superfamily
      5e-08   32.2   2.9      5e-08   32.2   2.9    2.4  2  Sugar_tr  Sugar (and other) transporter
  ------ inclusion threshold ------
       0.42   10.5   9.6       0.43   10.4   0.2    3.9  3  LapA_dom  Lipopolysaccharide assembly protein A domain
       0.72    8.1  12.3      0.011   14.1   3.0    2.5  3  OATP      Organic Anion Transporter Polypeptide (OATP) family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  166.4  23.8   1.8e-52   8.2e-49       4     353 .]      82     496 ..      79     496 .. 0.84
   2 !   12.4  13.5   1.2e-05     0.055      64     172 ..     420     528 ..     416     554 .. 0.63

  Alignments for each domain:
  == domain 1  score: 166.4 bits;  conditional E-value: 1.8e-52
       MFS_1   4 aaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlgaga 101
                 a f+s l+  i++p+lp  l+e++++s + +++ +t+y +++++a  ++G +sd  Grr+ ++l+++++ ++ + l++ ++++ +llvlr+lq++g+++
  EEA20245.1  82 ASFFSPLSGQIYFPVLP-VLTENYHLSQTLLNISVTTYLIFQGLAPSFMGTFSDASGRRPAYILAFIIYTAANIGLAL-QNSYaALLVLRCLQSAGSSG 178
                 789**************.******************************************************444445.88888*************** PP

       MFS_1 102 lfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee............ 188
                  ++ g+ +iad+++  erg+++g ++ag+ +G++lgp++gglla++lgWr+vf++l i+s   +v   ++    p ++++  +                
  EEA20245.1 179 TISFGYGVIADVTTTAERGKYLGPMAAGVMVGPALGPVIGGLLAQYLGWRSVFWFLVIISGGYVV---VYTILAPETHRKIVGDGSIlpaeswrlsilq 274
                 ***************************************************************88...5554444444444444444666888888888 PP

       MFS_1 189 .................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllalla 254
                                                  k  +p pl++ + +ll    ++ +++ ++l++fg + ++t lp++    +gl+  l++gl +  ++
  EEA20245.1 275 yvrirrrlarmtpaekkeydetqselmasqksrKIGFPNPLLS-FMILLELDAFM-IILYVALMMFGSMVMMTSLPSLYPAYYGLD-ELQVGLCFLPFG 370
                 8888888888888888888899999999999999999999999.98888888886.5555666656888899999997799*****.9*********** PP

       MFS_1 255 lvgailallagrlsdr...........................lgrrrrlllallllllaalglallavtssavllll..vlvliGfglgfvfpsllal 324
                   +a +a++ g+l+d                              r   ++l  ++l++++lg+ ++ +++ ++++    +++++Gf+l +++ sl++l
  EEA20245.1 371 TSSALGAIINGKLLDInykriarqhnfsidrkrgddltnfpieKARLQLTFLWSSILAATFLGYGWALNYKAPLAV-PlvMSFIMGFTLICTMNSLTTL 468
                 *****************99988888888776666665554432222444444455666666777777777333333.2359999*************** PP

       MFS_1 325 asdlappeeagtasglfntagslggalgp 353
                 ++d +p ++  tas++ n++++l ga+g+
  EEA20245.1 469 LADIFP-DRVSTASAAQNLLRCLLGAVGA 496
                 *****8.*****************99985 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 1.2e-05
       MFS_1  64 vlllglllfalglllllfa....sslwlllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailg.pllggllasslgWravfyil 157
                 ++l++ +l a + l   +a    ++l + lv+ +++G++  + + +  +l+ad+fp+ + + a +  ++   l  ++g +++ ++l+   g  ++f ++
  EEA20245.1 420 TFLWSSILAATF-LGYGWAlnykAPLAVPLVMSFIMGFTLICTMNSLTTLLADIFPD-RVSTASAAQNLLRCLLGAVGaAVVDSMLV-RMGLGWCFTFV 515
                 455666666666.22224445666666788888899999999999999999999998.99999999998888888888566667777.44444444444 PP

       MFS_1 158 aivsllafvlfllll 172
                  ++++ a+ l  l++
  EEA20245.1 516 SLLMVAAVSL--LWF 528
                 4444444223..454 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.2   2.9   1.1e-11     5e-08      20     210 ..      83     268 ..      38     352 .. 0.78
   2 ?   -0.6   9.1       0.1   4.5e+02     327     437 ..     425     530 ..     415     533 .. 0.72

  Alignments for each domain:
  == domain 1  score: 32.2 bits;  conditional E-value: 1.1e-11
                 GGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHH CS
    Sugar_tr  20 gafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGl 118
                 ++f+ l++++++  l + ++++  s++l+ ++v  +l+ + +   f+g+++d  GR+++++ a +++ ++++  a+ +   s+ +l+v R l   g  +
  EEA20245.1  83 SFFSPLSGQIYFPVLPVLTENYHLSQTLLNISVTTYLIFQGLAPSFMGTFSDASGRRPAYILAFIIYTAANIGLALQN---SYAALLVLRCLQSAGSSG 178
                 55667777777778888888788899999*************************************************...***************999 PP

                 HHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHC.CHHHHHHHHHHGGGS---HHHHHHTT-HHHHHHH CS
    Sugar_tr 119 asvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillgl.qlvpallllilllflPESPrylvekgkeeeakev 210
                 +  +    i+ +++++ Rg+  +    ++ +G  ++ ++g  l+++ +   wr  +++  +++   +++  +++PE+ r  v  g    a+  
  EEA20245.1 179 TISFGYGVIADVTTTAERGKYLGPMAAGVMVGPALGPVIGGLLAQYLG---WRSVFWFlVIISGGYVVVYTILAPETHRKIVGDGSILPAESW 268
                 99999999**************************************99...**88876155666778888899****9988888887766653 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.1
                 HHHHHHHHH...HHHHTTSS...CHHHHHHHHHHHHHHH..TTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHH CS
    Sugar_tr 327 maicfvilg.ivalllvakskaasivaivfialfialfa..lgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvf 422
                  ++++++lg + al ++a       +a+ +++ fi+ f+  ++++++   l++++fp +v s+a+a    +  l   + + +   ++ ++g g++f + 
  EEA20245.1 425 SILAATFLGyGWALNYKAP------LAVPLVMSFIMGFTliCTMNSLT-TLLADIFPDRV-STASAAQNLLRCLLGAVGAAVVDSMLVRMGLGWCFTFV 515
                 4556667763344444444......55555555555555213555555.788******99.77888999999999****************99999999 PP

                 HHHHHHHHHHHHHHS CS
    Sugar_tr 423 aglavlfiifvfffv 437
                   l+v+++   +f +
  EEA20245.1 516 SLLMVAAVSLLWFEY 530
                 999999988887765 PP

>> LapA_dom  Lipopolysaccharide assembly protein A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.2     0.018        79      35      62 ..     268     299 ..     267     300 .. 0.79
   2 ?   10.4   0.2   9.7e-05      0.43      15      40 ..     440     465 ..     430     484 .. 0.83
   3 ?   -0.1   0.5      0.19   8.6e+02      37      62 ..     525     551 ..     501     553 .. 0.50

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.018
    LapA_dom  35 wllslwsylrlrrelrrl....kkkikkleke 62 
                 w ls+++y+r rr+l r     kk+ ++ + e
  EEA20245.1 268 WRLSILQYVRIRRRLARMtpaeKKEYDETQSE 299
                 7799************9977767776666665 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 9.7e-05
    LapA_dom  15 velpLsllllvafgiGallgwllslw 40 
                  ++pL++ l+++f++G+ l++ +  +
  EEA20245.1 440 YKAPLAVPLVMSFIMGFTLICTMNSL 465
                 39***************999887665 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.19
    LapA_dom  37 lslw.sylrlrrelrrlkkkikkleke 62 
                 l ++  ++   ++ +r +k  +k+e+e
  EEA20245.1 525 LLWFeYVWGMGWRQKRWRKVAEKAERE 551
                 111112235666666666666666555 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.1     0.074   3.3e+02     268     351 ..      45     130 ..       6     151 .. 0.54
   2 ?   14.1   3.0   2.4e-06     0.011     135     232 ..     165     248 ..     150     389 .. 0.63
   3 ?   -3.9   0.3      0.68     3e+03     217     502 ..     454     485 ..     445     499 .. 0.48

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.074
                 xxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 268 kskssee...eelkslkdfpkalkrllknpifllvilssvfeillvaGfitF.lpkylEtqFslsaseAnlltGvvvipgaalGillg 351
                 ++ ++ e   ++++ l++  + +  +  ++ f++ + ++++ ++ ++G i F +   l ++++ls++  n+ + +++i+ + +  ++g
  EEA20245.1  45 ETPKD-EplnNTTTALSS-KPYTSFTTHQKWFIVGMATAASFFSPLSGQIYFpVLPVLTENYHLSQTLLNISVTTYLIFQGLAPSFMG 130
                 11111.122133333333.333444455566666666666666777777766333456666777777766666666666666555555 PP

  == domain 2  score: 14.1 bits;  conditional E-value: 2.4e-06
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 135 fflaqlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllklyvdidseisltpkdprWvgaWWlgflilgvllllaaip 232
                 +++  +l+ +G++  +++G+  i D +++ +   ylg + a  ++GpalG ++G+ll++ y               W   +W   +i+g  +++  i+
  EEA20245.1 165 LLVLRCLQSAGSSGTISFGYGVIADVTTTAERGKYLGPMAAGVMVGPALGPVIGGLLAQ-YL-------------GWRSVFWFLVIISGGYVVVYTIL 248
                 4555789999*********************************************9888.42.............35556666666666666665555 PP

  == domain 3  score: -3.9 bits;  conditional E-value: 0.68
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 217 lgflilgvllllaaiplffFPkelpkkkeerakkkseeesaekkeekkkkeksksseeeelkslkdfpkalkrllknpifllvilssvfeillvaGfit 315
                 +gf ++ ++  l+ +                                                                                    
  EEA20245.1 454 MGFTLICTMNSLTTL------------------------------------------------------------------------------------ 468
                 344444444444444.................................................................................... PP

                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 316 FlpkylEtqFslsaseAnlltGvvvipgaalGillgGllvkklklsakklaklvlvvsllsllllllllflgCetskvagvtvsyeelnqvenltssCn 414
                                                                                                                    
  EEA20245.1   - ---------------------------------------------------------------------------------------------------   -
                 ................................................................................................... PP

                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 415 sdCsssseakkksttettncscaaekegesesavaGkCdsdCkkklllflillflvsflgalgrvpallvilRcVkkedksfalGlql 502
                                                                                        l  + ++  s a + q 
  EEA20245.1 469 -----------------------------------------------------------------------LADIFPDRVSTASAAQN 485
                 .......................................................................44444444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (557 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       809  (0.0451224); expected 358.6 (0.02)
Passed bias filter:                      430  (0.0239835); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.69u 0.31s 00:00:01.00 Elapsed: 00:00:00.46
# Mc/sec: 3632.61
//
Query:       EEA20246.1  [L=505]
Description: NADH-ubiquinone oxidoreductase, subunit F, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.5e-47  161.2   0.0    2.5e-47  160.5   0.0    1.4  1  Complex1_51K  Respiratory-chain NADH dehydrogenase 51 Kd subu
    2.1e-29  101.4   0.3    4.3e-29  100.4   0.3    1.6  1  NADH_4Fe-4S   NADH-ubiquinone oxidoreductase-F iron-sulfur bi
    7.3e-09   35.4   0.0    1.9e-08   34.0   0.0    1.8  1  SLBB          SLBB domain
  ------ inclusion threshold ------
       0.11   12.6   0.3       0.19   11.8   0.3    1.3  1  DUF3568       Protein of unknown function (DUF3568)


Domain annotation for each model (and alignments):
>> Complex1_51K  Respiratory-chain NADH dehydrogenase 51 Kd subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  160.5   0.0   5.6e-51   2.5e-47       1     151 [.     101     276 ..     101     277 .. 0.96

  Alignments for each domain:
  == domain 1  score: 160.5 bits;  conditional E-value: 5.6e-51
  Complex1_51K   1 vkeagivGrGGagfPthvKlkakakkkk......kylivNaaEcEPgltkDrllmreepheileGlkiaaealgaekgvigvrdekpeaiealekal 91 
                   +k++g++GrGGagfP+++K+++++ k+       +yl+vNa+E+EPg++kDr +mr++p++++eG+ ++ +a++a+ ++i++r+e +e++ +l++a+
    EEA20246.1 101 IKASGLRGRGGAGFPSGLKYSFMNFKDWdkdprpRYLVVNADEGEPGTCKDREIMRKDPQKLIEGCLVVGRAMNATAAYIYIRGEFYEEATTLQRAI 197
                   799*******************997444788999*************************************************************** PP

  Complex1_51K  92 aeakaagl...........ldievvklagkYpaGeekaLiesltgr.evprgkpp..advgv.....vvnNveTlaavy 151
                   +ea++agl           +d+ ++++ag+Y++Gee+ Liesl+g+ + pr kpp  a vg+     +v NveT+a v+
    EEA20246.1 198 HEAYQAGLigknacgsgydFDVYIHRGAGAYVCGEETSLIESLEGKaGKPRLKPPfpAAVGLfgcpsTVTNVETVAVVP 276
                   *******************************************************8888888**************997 PP

>> NADH_4Fe-4S  NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.4   0.3   9.7e-33   4.3e-29       3      84 ..     391     472 ..     389     473 .. 0.97

  Alignments for each domain:
  == domain 1  score: 100.4 bits;  conditional E-value: 9.7e-33
                  HHHHHHHHHHH--S--HHHHIIIIHHHHHHHHHTBT---HHHHHHHHHHHHHHSS--SSTHHHHHHHHHHHHHHHHHHHHHH CS
  NADH_4Fe-4S   3 arrllefyaaesCGkCtpCreGtkrllelleriaagegteedldlleelaetikgtslCalgdsaanpvlsalrkFreefea 84 
                  + rl +fy++esCG+CtpCreG+k+ +++++r+++g+++e+++d+l+el+++++g+++Calg++ a+p++ ++r+Fr e+ea
   EEA20246.1 391 ISRLSHFYRHESCGQCTPCREGSKWTQQIMHRMEHGQAREREIDMLQELTKQVEGHTICALGEAFAWPIQGLIRHFRPELEA 472
                  67899**************************************************************************997 PP

>> SLBB  SLBB domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.0   0.0   4.3e-12   1.9e-08       2      57 ..     300     350 ..     299     351 .. 0.91

  Alignments for each domain:
  == domain 1  score: 34.0 bits;  conditional E-value: 4.3e-12
                 EEEESSBSS-EEEEEETT-BHHHHHHTTT-SBSS.........-E.EEE-SSSSS-- CS
        SLBB   2 VtVtGeVkrPgnyevpigttlsdlieqaGGltddadlksvnLarl.avipgGpmmgi 57 
                 ++++G+V++P+++e  + ++l++li+ ++G+ + ++        l avipgG++++i
  EEA20246.1 300 FCISGHVNNPCTVEEEMSIPLRELIDRHCGGVRGGWD------NLlAVIPGGSSTPI 350
                 79*************************8888888873......7899********98 PP

>> DUF3568  Protein of unknown function (DUF3568)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.3   4.3e-05      0.19      16      55 ..     164     202 ..     161     213 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 4.3e-05
     DUF3568  16 asCaalvagaa.agagtvayvnGelkaeyeanlkkvykAtl 55 
                  +C  lv+g a  +++++ y++Ge+++e  +  + + +A +
  EEA20246.1 164 EGC--LVVGRAmNATAAYIYIRGEFYEEATTLQRAIHEAYQ 202
                 689..677777679************996554444444433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (505 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       537  (0.0299515); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.56u 0.31s 00:00:00.87 Elapsed: 00:00:00.45
# Mc/sec: 3340.57
//
Query:       EEA20247.1  [L=709]
Description: SET domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0018   18.7   0.0     0.0064   16.9   0.0    2.0  2  SET       SET domain


Domain annotation for each model (and alignments):
>> SET  SET domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.0   3.6e-07    0.0064      74     169 .]     143     273 ..      47     273 .. 0.71
   2 ?   -2.8   0.0      0.41   7.4e+03     112     130 ..     549     573 ..     487     585 .. 0.56

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 3.6e-07
                 HHHHHHHHTHHHHHHHXTTTS.......X.............XXHCCCCC..HCCCHEEEETEEEEEECCC.................GTTGGGCEEXS CS
                 xxxxxxxxxxxxxxxxxxxxx.......x.............xxxxxxxx..xxxxxxxxxxxxxxxxxxx.................xxxxxxxxxxx RF
         SET  74 aekedtdaalkasskaesdln.......a.............skpeagaf..saiagysidaralksgnga.................gplarflNHsC 133
                 +e+e +  +l++ s a+s+         +              + e++ +   ++a+ +i +ra+ +   a                  pl++  NH  
  EEA20247.1 143 REEEGDLEWLGMTSLAASRERrlaiwrgNyergytmlkelgfEGVEGYTWdlYLWASTIISSRAFTAKVLAsvipelknaevdrvsvlLPLIDATNHK- 240
                 44555555555555555555544444330444445566666633444444569999999999999999999999***********************6. PP

                 SSSEEEEEEEETTSSEEEEEESSXBXTTEEEEEXTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         SET 134 dpNcnltvqnvlrgprvavfAtrdIkkGeEltidYg 169
                  p  ++++++  + + ++++   d+++GeE+ ++Yg
  EEA20247.1 241 -PLSKVEWRA--GTDSIGLVVMSDVAAGEEVGNNYG 273
                 .888889999..9**********************8 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.41
                 ETEEEEEECCC............GTTGGGCE CS
                 xxxxxxxxxxx............xxxxxxxx RF
         SET 112 daralksgnga............gplarflN 130
                 d++       +            + +a f+N
  EEA20247.1 549 DGTG------SnpentasgphaqFAYAAFIN 573
                 2222......122333355555788888888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (709 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       334  (0.018629); expected 358.6 (0.02)
Passed bias filter:                      317  (0.0176809); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.27s 00:00:00.89 Elapsed: 00:00:00.48
# Mc/sec: 4410.99
//
Query:       EEA20248.1  [L=1120]
Description: Sit4-associated protein (Sap185), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.4e-199  664.0   3.0   1.4e-199  664.0   3.0    2.7  3  SAPS      SIT4 phosphatase-associated protein


Domain annotation for each model (and alignments):
>> SAPS  SIT4 phosphatase-associated protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.5     0.053   9.5e+02     251     293 ..      52     101 ..      32     125 .. 0.45
   2 !  664.0   3.0  7.8e-204  1.4e-199       1     489 []     168     786 ..     168     786 .. 0.84
   3 ?   -2.8   0.4      0.11     2e+03     272     289 ..     892     943 ..     853    1021 .. 0.47

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.053
        SAPS 251 Devrerlleel.......tseeealedvsdeaskeesaesedltdkdedv 293
                 D+++++lle         +++++  +d +++ +++e+   +d t+kded+
  EEA20248.1  52 DHILKKLLEYVvapplinDDDNDDHDDDDTKTKSDEKVGGADDTKKDEDI 101
                 44444444433333333222233333333333333333333333333333 PP

  == domain 2  score: 664.0 bits;  conditional E-value: 7.8e-204
        SAPS   1 nenLldrkteemleFiksqenivekflkhidtpaimdlLlkiIstektesgtgiiewlksqdLisklldlLspeesediqssasdfLkaiItisanata 99 
                 ne L+d+kteemleF+ks ++iv+++l+h+d+p++mdlLlkiIs+ek+e+g+gi++wlk+++Li+ ll+ +s+e+s+++q+sa+dfLkaiItisanat+
  EEA20248.1 168 NEVLFDKKTEEMLEFFKSLKGIVPAILQHVDNPMVMDLLLKIISLEKVEGGQGIVDWLKDENLIPILLSYISSEHSSSMQTSAGDFLKAIITISANATQ 266
                 799************************************************************************************************ PP

        SAPS 100 nlqssigpneLtreLvseeivekLikimlkgksgsalvngvgiiielirknnsdydeenllytsleedppsmrdpiylghlLrlfsehlkdfqqlllep 198
                 n qs+igpn+Ltr+Lvs +++e+Li++ml+g  g++l++gvgi+ie+irknnsdyde+       ++  ps +dpiylg+lLr fs h++df++l+l++
  EEA20248.1 267 NEQSCIGPNSLTRQLVSAPCIEQLIGFMLQG--GNSLTVGVGIVIEVIRKNNSDYDENIGG----PDARPSIYDPIYLGTLLRQFSTHIPDFMALILSS 359
                 *******************************..*************************987....6********************************* PP

        SAPS 199 keks............klettlgekiepLGfeRfkiveLiaeLLhcsnmallnekkgeeivkerDevrerlleel........................ 261
                 k+++            +l++++g kiepLGf+Rfk++eL+aeLLhcsnm+llne ++e+++++rD  re+l++++                        
  EEA20248.1 360 KHTVvengqlkikdrgQLNSAWGHKIEPLGFDRFKTCELMAELLHCSNMGLLNEVGSEDYIRQRDIDRENLRAQGafdlnrkdvsgmaysenageseqe 458
                 **************************************************************************9999988888877777766666555 PP

        SAPS 262 ....tse.............eealedvs........................................................deaskeesaesedlt 287
                       e             ++++edv+                                                        +++ ++ s++++ lt
  EEA20248.1 459 qafrA-EaqsatienanasdDDGFEDVGsskdlgpeiksdsaeqrqaekaevhaqsaglhiedsiveetlkhsnkietpglapaESSIDPISPTTSGLT 556
                 55440.044455555555558888888888888888887777777666666666666666666666666666666666666666444444455555555 PP

        SAPS 288 dkdedvsleesksakd........................enkesdesesdtaeesseededdasseesalaeeteeklr................... 343
                 d++++++l+++++ +                         +    +e +s ++  ++ +++ ++ +             +                   
  EEA20248.1 557 DSVNEITLNKDEQGSSieksmdqanrsaephsedvpasttQ----SEPQSAETRPEEPASTIEERQ-------------Snesqathiedefapqiqyd 638
                 55555444444444447777776666554444334422220....111111111111111111111.............01122344445555777788 PP

        SAPS 344 ..kkpvvGDlLKiklvelkilptiLdlFfkYpwNNfLHnvVydivqqilngkmdrgynrfLavdLfekaklterilegqkesdesqaekkirlGYmGHl 440
                   ++pvvGD+LKi++ve+k++ptiLd+Ff++pwNNfLHnvVyd+vqq++ng+mdrgynr La+dLf+ +++te+i+egqk+sde+qa+k++rlGYmGHl
  EEA20248.1 639 hsGQPVVGDFLKIQFVEHKVVPTILDFFFRFPWNNFLHNVVYDVVQQVFNGSMDRGYNRCLAIDLFNAGRITEKIVEGQKRSDEAQATKNTRLGYMGHL 737
                 88************************************************************************************************* PP

        SAPS 441 tlIAeevvkfleryppellseeieekleneeWeeyveetLeetrekena 489
                 tlIAeevvkf+er+p+e ls+ +++k+ +++W +yve+tL+etre++na
  EEA20248.1 738 TLIAEEVVKFTERHPAEVLSQSVMDKVLHPDWVDYVEQTLSETRERDNA 786
                 ***********************************************96 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 0.11
        SAPS 272 s..................................deaskeesaesedltdk 289
                                                      ++++ +a++e+l+d+
  EEA20248.1 892 PassstsqpipilapppaplnivpsrarrqlaarlALHKQQADAAAENLNDQ 943
                 0333333333444444444443333333333322211111111111111111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1120 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       835  (0.0465726); expected 358.6 (0.02)
Passed bias filter:                      436  (0.0243181); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.84u 0.28s 00:00:01.12 Elapsed: 00:00:00.43
# Mc/sec: 7844.75
//
Query:       EEA20249.1  [L=218]
Description: SNF7 family protein (Cta1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.3e-43  148.6  14.6    1.6e-43  148.3  14.6    1.0  1  Snf7            Snf7
     0.0019   18.0   7.9     0.0024   17.6   6.9    1.7  1  DUF4201         Domain of unknown function (DUF4201)
     0.0027   17.8   3.6        1.9    8.6   0.0    3.1  3  bZIP_1          bZIP transcription factor
     0.0043   16.6   4.9     0.0064   16.0   4.9    1.3  1  Zwint           ZW10 interactor
     0.0069   16.4   2.9      0.012   15.5   2.3    1.7  1  Alpha-2-MRAP_C  Alpha-2-macroglobulin RAP, C-terminal domain
  ------ inclusion threshold ------
      0.016   15.6   6.2       0.71   10.4   1.0    2.8  3  NPV_P10         Nucleopolyhedrovirus P10 protein
       0.04   14.3   5.0        4.9    7.6   0.0    3.3  3  CLZ             C-terminal leucine zipper domain of cyclic nu
      0.043   13.9   0.0      0.093   12.8   0.0    1.5  1  HHH_2           Helix-hairpin-helix motif
       0.05   13.6   6.7        1.1    9.2   0.0    3.2  2  Prefoldin_2     Prefoldin subunit
      0.083   13.3   6.7        5.6    7.4   0.0    3.4  4  FlaC_arch       Flagella accessory protein C (FlaC)
        0.1   11.6   1.9       0.15   11.1   1.9    1.2  1  FAM199X         Protein family FAM199X
       0.15   12.6   2.7       0.45   11.1   2.7    1.9  1  DUF4844         Domain of unknown function (DUF4844)
       0.47    9.0   7.5        3.4    6.2   7.5    1.9  1  FapA            Flagellar Assembly Protein A
        8.4    6.1  11.5        6.3    6.5   6.1    2.1  2  EMC3_TMCO1      Integral membrane protein EMC3/TMCO1-like


Domain annotation for each model (and alignments):
>> Snf7  Snf7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  148.3  14.6   1.2e-46   1.6e-43       2     170 ..      12     192 ..      11     195 .. 0.94

  Alignments for each domain:
  == domain 1  score: 148.3 bits;  conditional E-value: 1.2e-46
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTT-...........HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        Snf7   2 airsLrkaerkldkkqeslekkikkleaelkklakkgn...........kdralllLKqkkryekqldqldnqlanleqvslaienlksnkevlnamkq 89 
                 +++ L  a+ ++d++  s++ k++ l++el  ++  +            +++al++L ++k+ye q+dql++q++n+eq+++  +nlk+ +++++amk+
  EEA20249.1  12 PKPTLDSAISNVDNRVASIDVKLAALNSELSTYQSRIAkmrdgpgktalRQKALKVLQRRKQYEAQRDQLSQQSWNMEQANMMQDNLKNVMTTVDAMKT 110
                 678999***************************99988888999******************************************************* PP

                 HHHHHHHHHHCTCCHHHHHHHHHHHHHHHHHTCHHHHHHHHHTT-GGTTHHHHHHHHHHHHHHHHHCSH..HHHHHHHTXXX CS
        Snf7  90 gakamkamnkkvdidkidklmdeiedqmekaeeisEalsrslddadeedEeeleaeLdaLeqelgdeell.desvklpevPs 170
                 ++ka+k+++ k+didki++++de++d m++ +ei+E +sr++d+++++dE+el+aeL+aL +e + e+    +++ +p++ +
  EEA20249.1 111 TTKALKKQYGKIDIDKIERMQDEMADLMDIGNEINESISRAYDIPEDVDEAELDAELEALGEESLFENPMmGDAEAMPSFLQ 192
                 ***************************************************************8888743566777777665 PP

>> DUF4201  Domain of unknown function (DUF4201)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   6.9   1.9e-06    0.0024      82     169 ..      30     120 ..      16     126 .. 0.85

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 1.9e-06
     DUF4201  82 lkeklhmleselselkkelkekeer..laklrkelykvklerdklrkqneklkqqggllrvPaLlkD.YdktkekveekrksvkkLrrkvk 169
                 +  kl +l+sels+ ++++ ++ +   +++lr++  kv ++r+++++q+++l+qq+++++    ++D  ++ +  v+ ++ + k L++++ 
  EEA20249.1  30 IDVKLAALNSELSTYQSRIAKMRDGpgKTALRQKALKVLQRRKQYEAQRDQLSQQSWNMEQANMMQDnLKNVMTTVDAMKTTTKALKKQYG 120
                 5569999***************99533889************************************9555666778888888888887765 PP

>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.6   0.0    0.0015       1.9      29      61 ..      21      53 ..      18      54 .. 0.91
   2 !    7.4   1.1    0.0035       4.5      23      62 ..      71     111 ..      63     113 .. 0.83
   3 ?   -0.7   0.0       1.2   1.6e+03      33      56 ..     125     148 ..     115     150 .. 0.72

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0015
                HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1 29 eeLerrvkaLekeNksLkseleelkkevekLks 61
                ++  +rv+ ++ + ++L sel++++  ++k+++
  EEA20249.1 21 SNVDNRVASIDVKLAALNSELSTYQSRIAKMRD 53
                66789*************************985 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0035
                 HHH..HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  23 RKq..aeieeLerrvkaLekeNksLkseleelkkevekLksk 62 
                 RKq  a+ ++L++++  +e+ N+ +++ l++ + +v+ +k+ 
  EEA20249.1  71 RKQyeAQRDQLSQQSWNMEQANM-MQDNLKNVMTTVDAMKTT 111
                 4441155689*************.***************985 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 1.2
                 HHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  33 rrvkaLekeNksLkseleelkkev 56 
                 ++ + ++ e+++L +  +e+++ +
  EEA20249.1 125 DKIERMQDEMADLMDIGNEINESI 148
                 567777788888877777777665 PP

>> Zwint  ZW10 interactor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   4.9     5e-06    0.0064      89     167 ..      47     125 ..      18     139 .. 0.84

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 5e-06
       Zwint  89 alpkveeaqrkraqlqealeqlqakkqvameklrvaqkqwqlqqekhlq.hlaevsaevrerqtgtqqelerlyqelgtl 167
                  ++k+ +   k a  q+al+ lq +kq  +++ + +q+ w+++q   +q +l +v + v   +t t+  l++ y ++++ 
  EEA20249.1  47 RIAKMRDGPGKTALRQKALKVLQRRKQYEAQRDQLSQQSWNMEQANMMQdNLKNVMTTVDAMKTTTK-ALKKQYGKIDID 125
                 567888888999999********************************9956999***9999998775.566666666654 PP

>> Alpha-2-MRAP_C  Alpha-2-macroglobulin RAP, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   2.3   9.7e-06     0.012     135     198 ..      33     109 ..      28     121 .. 0.82

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 9.7e-06
  Alpha-2-MRAP_C 135 eLeslkeELkhyesrleklrhlqaelelseeklk.............deekkkekkekhkkleekikklgrkveklh 198
                      L++l +EL+ y+sr+ k+r    + +l+++ lk             + ++++ ++e+++++++++k++ ++v+ ++
      EEA20249.1  33 KLAALNSELSTYQSRIAKMRDGPGKTALRQKALKvlqrrkqyeaqrdQLSQQSWNMEQANMMQDNLKNVMTTVDAMK 109
                     699*****************999988888888888888888888775556667788899999999999999987665 PP

>> NPV_P10  Nucleopolyhedrovirus P10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.1    0.0059       7.6      11      38 ..      18      45 ..      15      54 .. 0.82
   2 ?   -0.7   0.1       1.6     2e+03      39      49 ..      76      86 ..      58     102 .. 0.45
   3 ?   10.4   1.0   0.00056      0.71      10      72 ..      95     156 ..      92     160 .. 0.88

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0059
     NPV_P10 11 adikavddkVdalqqqvddvqenlpdvt 38
                ++i++vd++V +++ +++ ++++l + +
  EEA20249.1 18 SAISNVDNRVASIDVKLAALNSELSTYQ 45
                6899999999999999999999988755 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 1.6
     NPV_P10 39 elnekLdaqsa 49
                   ++L +qs 
  EEA20249.1 76 AQRDQLSQQSW 86
                33333333333 PP

  == domain 3  score: 10.4 bits;  conditional E-value: 0.00056
     NPV_P10  10 radikavddkVdalqqqvddvqenlpdvtelnekLdaqsaqLaeletkvenIqdiLnpde.vPd 72 
                  ++ k+v + Vda+++  + ++++  +++   +k++++++++a+l +  ++I++  +    +P+
  EEA20249.1  95 QDNLKNVMTTVDAMKTTTKALKKQYGKID--IDKIERMQDEMADLMDIGNEINESISRAYdIPE 156
                 57789**********************99..89************9999999998885556665 PP

>> CLZ  C-terminal leucine zipper domain of cyclic nucleotide-gated channels
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   0.0    0.0038       4.9      26      62 ..      13      49 ..       6      52 .. 0.70
   2 ?    5.7   0.8     0.014        18      23      55 ..      88     120 ..      76     125 .. 0.83
   3 ?   -0.4   0.0       1.2   1.5e+03      39      52 ..     126     139 ..     124     151 .. 0.67

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0038
         CLZ 26 qkeleekverLessLeaLqtrlarLlaeyessqrkLk 62
                + +l++ ++++++++ +++ +la L +e+++ q+++ 
  EEA20249.1 13 KPTLDSAISNVDNRVASIDVKLAALNSELSTYQSRIA 49
                5567777777777777888888888877777777664 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.014
         CLZ  23 gaeqkeleekverLessLeaLqtrlarLlaeye 55 
                  ++++ ++++++++ ++++a++t  + L ++y 
  EEA20249.1  88 MEQANMMQDNLKNVMTTVDAMKTTTKALKKQYG 120
                 4678889999*****************999986 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 1.2
         CLZ  39 sLeaLqtrlarLla 52 
                 ++e +q+ +a L++
  EEA20249.1 126 KIERMQDEMADLMD 139
                 45666666666664 PP

>> HHH_2  Helix-hairpin-helix motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   7.2e-05     0.093      14      57 ..     110     154 ..     109     158 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 7.2e-05
       HHH_2  14 ktAklLakrFk..sldaLkkasleeLlevddiGeeiAqsivefFen 57 
                 +t k+L k+++  ++d++++++ +e++ + diG+ei +si + ++ 
  EEA20249.1 110 TTTKALKKQYGkiDIDKIERMQ-DEMADLMDIGNEINESISRAYDI 154
                 7899*******66678888775.89***************987765 PP

>> Prefoldin_2  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.0    0.0009       1.1      59      97 ..      15      53 ..      13      55 .. 0.93
   2 ?    0.9   5.8      0.35   4.5e+02       5      47 ..      72     114 ..      58     122 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0009
                 -HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Prefoldin_2 59 dkeevkeeLeerketlekeiktlekqleklekeleelke 97
                 +++++++++++r ++++ ++++l+++l++ + +++++++
   EEA20249.1 15 TLDSAISNVDNRVASIDVKLAALNSELSTYQSRIAKMRD 53
                 68999******************************9986 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.35
                  HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS-TT--E CS
  Prefoldin_2   5 nkfqqlqqqlqqlaqqikqletqlkelelvleelelldedtkv 47 
                  ++++  ++ql+q   +++q+++  ++l+ v ++++ ++ +tk 
   EEA20249.1  72 KQYEAQRDQLSQQSWNMEQANMMQDNLKNVMTTVDAMKTTTKA 114
                  5677777777777777777777777777777777777777554 PP

>> FlaC_arch  Flagella accessory protein C (FlaC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.0    0.0044       5.6       2      34 ..      20      52 ..      19      54 .. 0.83
   2 ?    4.5   0.6     0.035        45      15      40 ..      90     115 ..      75     122 .. 0.76
   3 ?    2.6   3.7      0.14   1.8e+02       8      43 ..     104     140 ..      92     146 .. 0.64
   4 ?    3.5   0.4     0.075        96       8      37 ..     118     148 ..     112     158 .. 0.66

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0044
   FlaC_arch  2 idelEnklsklsteletvkkeneelsksveelk 34
                i +++n++ +++++l+ + +e++  ++ + ++ 
  EEA20249.1 20 ISNVDNRVASIDVKLAALNSELSTYQSRIAKMR 52
                567889999999999999999999998888876 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.035
   FlaC_arch  15 eletvkkeneelsksveelkenVkdl 40 
                 + ++++++++++ ++v+ +k + k l
  EEA20249.1  90 QANMMQDNLKNVMTTVDAMKTTTKAL 115
                 55788888888888888888877665 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.14
   FlaC_arch   8 klsklsteletvkkeneels.ksveelkenVkdllsL 43 
                  ++ ++t+ + +kk+  ++  +++e+++++  dl+++
  EEA20249.1 104 TVDAMKTTTKALKKQYGKIDiDKIERMQDEMADLMDI 140
                 4455556666666666666546777777777777765 PP

  == domain 4  score: 3.5 bits;  conditional E-value: 0.075
   FlaC_arch   8 klsklst.eletvkkeneelsksveelkenV 37 
                 + +k+++ ++e +++e+ +l +  +e++e++
  EEA20249.1 118 QYGKIDIdKIERMQDEMADLMDIGNEINESI 148
                 4556666667777777777777777777766 PP

>> FAM199X  Protein family FAM199X
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   1.9   0.00012      0.15     233     303 ..      22      90 ..       7     108 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00012
     FAM199X 233 svgssaansaanisrahsdsnlssaaerirdskkrskqrklqqkalrkrqlkeqrqarkerlsglflneev 303
                  v +    ++ ++  a  +s+ls+   ri   +    +  l+qkal+  q ++q +a++++ls    n e 
  EEA20249.1  22 NVDNR--VASIDVKLAALNSELSTYQSRIAKMRDGPGKTALRQKALKVLQRRKQYEAQRDQLSQQSWNMEQ 90 
                 23222..366778889999***********9999999**************************98877765 PP

>> DUF4844  Domain of unknown function (DUF4844)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   2.7   0.00035      0.45      62      98 ..     104     140 ..      28     148 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00035
     DUF4844  62 lqkklkltlerldkqylelDtEdrerildYmeelmdi 98 
                     +k+t + l+kqy+++D +  er+ d m +lmdi
  EEA20249.1 104 TVDAMKTTTKALKKQYGKIDIDKIERMQDEMADLMDI 140
                 457899******************************9 PP

>> FapA  Flagellar Assembly Protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   7.5    0.0027       3.4     334     434 ..      22     118 ..       7     162 .. 0.54

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0027
        FapA 334 elkeklkeleeeleeleeeleklkkkikklpklkaekqlesekkeqlkklletkeklkeeleeleeelkelkeeleskkeeakikvnkeiypgvkikig 432
                 +++++++ ++ +l +l++el +++++i+k+++   +   ++ +++ lk l++ k+   ++ +  ++  +  ++++ +  + +++ ++  +++ ++  ++
  EEA20249.1  22 NVDNRVASIDVKLAALNSELSTYQSRIAKMRDGPGK---TALRQKALKVLQRRKQYEAQRDQLSQQSWNMEQANMMQD-NLKNVMTTVDAMKTTTKALK 116
                 566677777777777777777777777777773333...334444444444444333333333333333333333333.22222332233333222222 PP

        FapA 433 kk 434
                 k+
  EEA20249.1 117 KQ 118
                 22 PP

>> EMC3_TMCO1  Integral membrane protein EMC3/TMCO1-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   6.1    0.0049       6.3      50      92 ..      63     105 ..      32     112 .. 0.76
   2 ?    4.0   0.7     0.029        37      46      82 ..     100     136 ..      97     141 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0049
  EMC3_TMCO1  50 rekelqkrarelqkngdklklkklekrqeelmedqsemmmdqm 92 
                 +  ++++r ++++ ++d+l++++ +++q+ +m+d+ +  m + 
  EEA20249.1  63 KALKVLQRRKQYEAQRDQLSQQSWNMEQANMMQDNLKNVMTTV 105
                 33356789999999********************998766554 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.029
  EMC3_TMCO1  46 keqkrekelqkrarelqkngdklklkklekrqeelme 82 
                 ++ ++  +++  +++l+k+++k+  +k+e++q e+++
  EEA20249.1 100 NVMTTVDAMKTTTKALKKQYGKIDIDKIERMQDEMAD 136
                 56666778889999*******************9975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (218 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2051  (0.114396); expected 358.6 (0.02)
Passed bias filter:                      684  (0.0381505); expected 358.6 (0.02)
Passed Vit filter:                        85  (0.00474092); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.60u 0.30s 00:00:00.89 Elapsed: 00:00:00.48
# Mc/sec: 1358.31
//
Query:       EEA20250.1  [L=569]
Description: transporter protein smf2 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.9e-92  309.0  18.0    7.2e-92  308.1  18.0    1.4  1  Nramp     Natural resistance-associated macrophage protein


Domain annotation for each model (and alignments):
>> Nramp  Natural resistance-associated macrophage protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  308.1  18.0     4e-96   7.2e-92       2     351 ..     132     510 ..     131     514 .. 0.94

  Alignments for each domain:
  == domain 1  score: 308.1 bits;  conditional E-value: 4e-96
       Nramp   2 atdlqaGaqfGykLlwvlllstllaillqelsarLGlvTgkglaelirerlpkkvsillwilaelaiiatdlaeviGaAialnllfgipllvgvlitav 100
                 atd++aGaq  y+Ll v+++s+l+a++lq+l+++LG vTg +lae++r++lp++++i+l+il e aiiatd+aeviG+Aialnll+++pl++g++it++
  EEA20250.1 132 ATDAAAGAQSKYALLFVVMMSNLFAVFLQSLCIKLGSVTGLNLAENCRAHLPRWLTIILYILSEAAIIATDIAEVIGSAIALNLLLNVPLVAGCIITMA 230
                 89************************************************************************************************* PP

       Nramp 101 lvllllflek.....ggyrklEaliialvlvialsFiaelflvk.pdwgevlkglvvPslpg..keslllavgilGatvmphnlflhsslvqerkitid 191
                 +vl+ll++ +      g r +E ++++lvl ++++F ++l l+k p++gev++g + Ps      + l+   gilGatvmph lfl s +vq r ++ d
  EEA20250.1 231 DVLILLIFYRpqgsmWGLRAFEMFVALLVLGVVVCFCIQLSLLKvPSVGEVFRGYL-PSPAViqGSGLYQSCGILGATVMPHSLFLGSGTVQPRLKEFD 328
                 *******96422222579***********************9995679******99.9998888899*************************9997775 PP

       Nramp 192 r....................seke....ealkyeriDtiial.ivaflinlailivaAavly.sggkdvesledaaeaLepllGskaasvlFaigLla 264
                                      s         lky+ i+ ++ l ++a++in+ailivaAa+ly + g+d ++l++++e+L+  +  +aa ++F+++Ll 
  EEA20250.1 329 IdaghmepsgsdddsseiyrpS--IhairGCLKYSIIELTLCLfTFALFINSAILIVAAAALYgTPGADNADLFGIHELLSRSIA-PAAGTIFGLALLL 424
                 58899***99988666555442..05567799**********989******************999999****************.7************ PP

       Nramp 265 aGlsStitgtlagqyvmegflglrislwlrrlitralafvpalivilligaelelvkllvlsqvllslllPfaliplllltsskklM 351
                 +Gls+ i++t+agq+v eg+++++ ++w rrl+tr++++vp +i+++++g ++   ++l +sqv+ls++lPf+++pl+++t + k M
  EEA20250.1 425 SGLSAGIVCTIAGQMVSEGMINWSCRPWIRRLLTRVISIVPSVIIAAAVGRKGL-DTALTASQVVLSVILPFVVAPLIYFTGRNKFM 510
                 ****************************************************99.9*****************************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (569 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       636  (0.0354733); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.31s 00:00:00.96 Elapsed: 00:00:00.50
# Mc/sec: 3408.77
//
Query:       EEA20251.1  [L=811]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-17   63.7   2.5    3.9e-16   59.2   2.5    2.4  1  Drf_GBD   Diaphanous GTPase-binding Domain


Domain annotation for each model (and alignments):
>> Drf_GBD  Diaphanous GTPase-binding Domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.2   2.5   2.2e-20   3.9e-16       4     156 ..     304     541 ..     301     561 .. 0.91

  Alignments for each domain:
  == domain 1  score: 59.2 bits;  conditional E-value: 2.2e-20
     Drf_GBD   4 pdeeeidklFeelleelnlpeekreallalpiekKwqlvvqdkkkkakke................................................. 53 
                 +d+++i+++Fe+ll+ +n+p + r+++++l+++ K+ ++++++  ++  +                                                 
  EEA20251.1 304 QDPKQIESEFEKLLDARNIPMNMRDKMRSLDTNIKADFIQKNQAESSVPNsatsstfdsagrrgrkddrsapsqtrdkslrslsrarspfstsrgdtsp 402
                 6899***********************************88877665555999********************************************** PP

     Drf_GBD  54 ................................eklsksksksneeespesyvkklkddslke....kqlesLrVaLrtqplsWvkrFieleGlvaLlnv 116
                                                  +  + ks+++ ++ p +++++l++ +  e      l++Lr  Lr++ + Wv +Fi  +G+  ++++
  EEA20251.1 403 kkhqksnsassfkrpksvdlsrpymlptastsSTSLHAKSQADTFADPADFIHYLREVQKPElvevGKLHKLRLLLRNETVAWVDSFITGDGMDEIIQL 501
                 *****************************9877777888999999*********99988777788899******************************* PP

     Drf_GBD 117 LskinekkaeeeedlkkeyeiikClKalmNnkvGldavla 156
                 L +i + + +ee++ +  +e + ClKal+ ++v l++  a
  EEA20251.1 502 LYRIMKVEWREEHEDNLLHEALLCLKALCTTSVALQRLTA 541
                 ***********9999***************9998887665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (811 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       883  (0.0492498); expected 358.6 (0.02)
Passed bias filter:                      441  (0.024597); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.28s 00:00:00.96 Elapsed: 00:00:00.44
# Mc/sec: 5539.09
//
Query:       EEA20252.1  [L=432]
Description: salicylate hydroxylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.5e-14   52.8   9.2    3.8e-13   49.4   9.2    2.4  1  FAD_binding_3   FAD binding domain
    3.3e-06   26.5   0.3    0.00062   19.1   0.1    2.4  2  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    2.2e-05   24.6   0.4    5.4e-05   23.3   0.4    1.7  1  NAD_binding_8   NAD(P)-binding Rossmann-like domain
    0.00025   20.2   0.0      0.042   12.9   0.0    2.1  2  SE              Squalene epoxidase
    0.00047   19.6   0.6      0.065   12.5   0.0    2.2  2  Amino_oxidase   Flavin containing amine oxidoreductase
    0.00086   19.3   2.7        0.9    9.5   1.7    2.6  2  NAD_binding_9   FAD-NAD(P)-binding
     0.0011   18.1   0.1     0.0016   17.6   0.1    1.4  1  FAD_binding_2   FAD binding domain
     0.0035   17.0   6.2     0.0062   16.2   4.8    1.9  2  DAO             FAD dependent oxidoreductase
  ------ inclusion threshold ------
      0.047   12.8   0.1      0.086   11.9   0.1    1.5  1  GIDA            Glucose inhibited division protein A
      0.087   12.1   0.1       0.15   11.3   0.1    1.3  1  Thi4            Thi4 family
      0.094   11.4   0.9       0.16   10.7   0.9    1.3  1  HI0933_like     HI0933-like protein
       0.29    9.9   4.4        3.9    6.2   0.0    2.7  3  Trp_halogenase  Tryptophan halogenase
        1.5    9.5   3.3        1.8    9.2   1.8    2.1  1  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
        1.9    7.4   5.6         22    4.0   0.0    2.9  3  Lycopene_cycl   Lycopene cyclase protein


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.4   9.2     3e-16   3.8e-13       3     348 ..      12     373 ..      10     374 .. 0.75

  Alignments for each domain:
  == domain 1  score: 49.4 bits;  conditional E-value: 3e-16
                    EEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSSS--EE...EHHHHHHHHH..TT-HHHHHHHSEECCCCEEEEEEECCCC....CEEEEE CS
  FAD_binding_3   3 dVlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlpradgl...nqrtmellrq..lGledrilaegapnelmgealynelsdt....pkarad 89 
                    +V+IVG+G  Gl+la  L ++ v+v + e  s   + + +  +     r m l++   + + d+++ + a +e+ + + ++ ++ +    ++a  +
     EEA20252.1  12 TVAIVGGGIGGLTLAIGLLRRNVSVAIYEAASAFGEVGLGLSIgpaAHRAMPLIDPqiRDIYDSLITTHADSEGYERFRQTWFEVIwatgEEAGQK 107
                    79**************999999**********9988887666522257999999743367999999999899988888888755557668677776 PP

                    HH.CHHCST-CEE--HHHHHHHHHHHHHHHTEEETCSEEEECCEECCCCCCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHHHTGG.EEEEEEEE CS
  FAD_binding_3  90 le.lesspervtvypqteleriLvehaeerglqvrfktevesleqdeegvtaevrdketgeeetvrakYlvGaDGgrStvrktlgie.fegeetvy 183
                    l  l++ p+  t++  ++++++Lv+  +  g   +f+++++ l+++  gvt  + d +      + a+ +vG+DG rS+v ++l  + +e ++  y
     EEA20252.1 108 LMtLNALPSGQTTVRRSDFLNALVNL-VPDG-VAQFGKRLVKLKEEPAGVTLSFEDGT-----SIVADVVVGCDGIRSRVKESLFPDeVEQFNPRY 196
                    66578999999*************98.6666.45788999999999999988777663.....6*******************9776699998884 PP

                    EEEEEEEEEEC-SCCCTTC........CEEEEECCTTEEEEEECCETEEEEEEEEECCE-GGGS.CCCHHHHHHHHHHHHHHT.....TSSCEEEE CS
  FAD_binding_3 184 eagvldvlfdadlsdivep........lvlilsaesrgvmviPlentlerfyvqvearaekeer.sekfteeevkarlreivg.....ektldvei 265
                     +g+ +  +  d++ +ve         +++ + +        P  ++++   v v +++ ++++ +++  +e  ++++++ +g      +++   +
     EEA20252.1 197 -SGMYGYRAVLDMETMVEAvgddrakvSTWYIGKGAYA-ITYPIMRAKK---VNVGLYTLNDTWdNDAWVREASREDMERDFGymgdyVNKIMKYM 287
                    .5666666555666666665557777755555555554.4445554233...44444444444423444444455555555552221235566678 PP

                    EEEEEEEE.EEEEESSSEETTEEE-GGGTEEE-STTSHHHHHHHHHHHHHHHHHH..HHHTTSS-GGGGHHHHHHHHHHHHHHHHH CS
  FAD_binding_3 266 eevsawtv.aqrvaekyrkgrvflaGDAaHihpPtgGqGlNtaiqDavnLawkLa..avlkGeAkeelLdtYeeerravaqavvdf 348
                    +++s+w + ++    ++ k +v + GDAaH+ +P +G G   ai+Da+ La  La   v + e   +  ++Y++ rr+++q+vv+ 
     EEA20252.1 288 TDASQWAIfEHPHIPTFAKSKVAILGDAAHASTPHQGAGAGQAIEDAHVLAELLAdkRVTTPEHVAAAFQAYDAVRRERSQKVVTS 373
                    8888888735678899**************************************944589999999*****************975 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.1   4.8e-07   0.00062       2      43 ..      12      53 ..      11     114 .. 0.81
   2 !    5.3   0.0    0.0077       9.9     202     240 ..     141     179 ..     133     191 .. 0.87

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 4.8e-07
                 SEEEE--SHHHHHHHHHHHHHTS-EEEEETTHCHHHCSHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  2 dvvviGgGpAGlaaaltlaqagakvtlvelegtclnggclls 43
                  v+++GgG++Gl++a+ l + ++ v+++e+  ++  +g  ls
   EEA20252.1 12 TVAIVGGGIGGLTLAIGLLRRNVSVAIYEAASAFGEVGLGLS 53
                 69**************************97776665555554 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0077
                  ESCEEEEEEETTEEEEEEETTSCEEEESEEEE-S-EEES CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 202 lgtsvkeidgngeklevvledgeeidadlvvvavGvrps 240
                  +g++ +++++++  +++  edg++i ad vv + G+r +
   EEA20252.1 141 FGKRLVKLKEEPAGVTLSFEDGTSIVADVVVGCDGIRSR 179
                  6777888898888999*******************9976 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.3   0.4   4.2e-08   5.4e-05       1      32 [.      15      46 ..      15      75 .. 0.94

  Alignments for each domain:
  == domain 1  score: 23.3 bits;  conditional E-value: 4.2e-08
                   EE--SHHHHHHHHHHHCCTEEEEEE-SSSSSS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekrdrlG 32
                   IvG+G++Gl++A  L +++++v ++e+++ +G
     EEA20252.1 15 IVGGGIGGLTLAIGLLRRNVSVAIYEAASAFG 46
                   9***************************9988 PP

>> SE  Squalene epoxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.3   0.0    0.0067       8.6       2      44 ..     167     210 ..     166     243 .. 0.84
   2 !   12.9   0.0   3.3e-05     0.042     130     198 ..     307     374 ..     274     385 .. 0.85

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0067
          SE   2 AkltvvcDGifsklRkels.dnkvevtssfvGlvlknaelpkkn 44 
                 A + v cDGi s+++ +l  d++ + +  + G++   a l +++
  EEA20252.1 167 ADVVVGCDGIRSRVKESLFpDEVEQFNPRYSGMYGYRAVLDMET 210
                 778899************98999999999999998888777665 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 3.3e-05
          SE 130 kGlillGDalnmRHPltggGmtvalnDivllskllkpledlsdeekvleelksfyvkRkeldavvnvLs 198
                 + + +lGDa     P  g+G   a++D+ +l++ll ++  ++  e+v+ +++ +   R+e +  v + s
  EEA20252.1 307 SKVAILGDAAHASTPHQGAGAGQAIEDAHVLAELLADK-RVTTPEHVAAAFQAYDAVRRERSQKVVTSS 374
                 45789********************************9.89999**********999998887666555 PP

>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.2   0.3    0.0084        11       1      27 [.      20      46 ..      20      46 .. 0.92
   2 !   12.5   0.0   5.1e-05     0.065     210     257 ..     124     171 ..      81     177 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.0084
                   HHHHHHHHHHHHTTEEEEEEESSSSSB CS
  Amino_oxidase  1 laGLaaArqLlsaGfdVtvlEardrvG 27
                   + GL+ A  Ll+++++V ++Ea + +G
     EEA20252.1 20 IGGLTLAIGLLRRNVSVAIYEAASAFG 46
                   68********************88776 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 5.1e-05
                    HHHHHHHHHTTTTEEEETSEEEEEEEEETTCEEEEETTSTEEEESEEE CS
  Amino_oxidase 210 sqlpealaeelrgldirlntrVkeikregdgvtvtledgevveaDaVv 257
                    s   +al +  +++  ++++r+ ++k e+ gvt+ +edg+++ aD Vv
     EEA20252.1 124 SDFLNALVNLVPDGVAQFGKRLVKLKEEPAGVTLSFEDGTSIVADVVV 171
                    6677788888889999*****************************998 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.5   1.7    0.0007       0.9       1      37 [.      14      46 ..      14      51 .. 0.84
   2 !    8.0   0.0     0.002       2.5     102     154 ..     125     175 ..      98     177 .. 0.90

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.0007
  NAD_binding_9  1 aivGaGprGlavlerLlarakkkspleitlfdpsep.g 37
                   aivG+G+ Gl+++  Ll+r+     +++ +++ +++ g
     EEA20252.1 14 AIVGGGIGGLTLAIGLLRRN-----VSVAIYEAASAfG 46
                   8******************5.....9999999854425 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.002
  NAD_binding_9 102 dlfeellarlpegvtvevhraevvdleeradgqavlladgaslaadaVvLAlG 154
                    d++++l++ +p+g  v  + ++ v+l+e+++g+++  +dg+s+ ad Vv + G
     EEA20252.1 125 DFLNALVNLVPDG--VAQFGKRLVKLKEEPAGVTLSFEDGTSIVADVVVGCDG 175
                    6777888878886..788999***************************98866 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.1   1.3e-06    0.0016       2      98 ..      13     110 ..      12     158 .. 0.69

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 1.3e-06
                    EEEE--SHHHHHHHHHHHHTTT-EEEEESSSGGGS.GGGG--S-EE-TT..SSGGSTC.CHHHHHH.HHHHHHTTT-S-HHHHHHHHHTHHHHHHH CS
  FAD_binding_2   2 viViGsGlAGLaAAleaaeaGlkvavvekeqefgg.atawsqGgidavlspeqkkagikdspelhr.tdtlkaldeladqplveafveaapeavde 95 
                    v ++G+G++GL+ A+ + +++ +va+ e +++fg   +  s G ++  +  +  + +i+d  ++ + t + +++ e+  q + e++ ++++ea + 
     EEA20252.1  13 VAIVGGGIGGLTLAIGLLRRNVSVAIYEAASAFGEvGLGLSIGPAAHRA-MPLIDPQIRDIYDSLItTHADSEGYERFRQTWFEVIWATGEEAGQK 107
                    89***************************99988655555555444333.2222333444333333023334444444666666666666666666 PP

                    HHH CS
  FAD_binding_2  96 Lee 98 
                    L+ 
     EEA20252.1 108 LMT 110
                    655 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   4.8   4.9e-06    0.0062       2      33 ..      13      46 ..      12      71 .. 0.92
   2 ?   -0.2   0.0      0.44   5.7e+02     168     227 ..     144     206 ..      74     294 .. 0.63

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 4.9e-06
                EEEECTSHHHHHHHHHHHHTT..EEEEESSSSTT CS
         DAO  2 vviiGGGiiGlstAyeLarrg..Vtllekgdiag 33
                v+i+GGGi Gl+ A  L rr+  V+++e+++ +g
  EEA20252.1 13 VAIVGGGIGGLTLAIGLLRRNvsVAIYEAASAFG 46
                99****************99899*******8877 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.44
                 CEEEEEEEETCEEEEE....EECTEEEEEEEEEEE--GGGHH..HHHTT.CTT....TSEEEEEEEEEEEE CS
         DAO 168 evtgleeedgkvwgve....rttpgendaadavVnaaGawsd..llgll.kel....dlpispvrgqvlvl 227
                 + ++l+ee    +gv     +   g+   ad vV + G+ s+  +   l ++     +++ s++ g+  vl
  EEA20252.1 144 RLVKLKEE---PAGVTlsfeD---GTSIVADVVVGCDGIRSRvkE--SLfPDEveqfNPRYSGMYGYRAVL 206
                 45556443...2233221222...433235778888887776431..222222222244555555555555 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.1   6.8e-05     0.086       2      71 ..      13      85 ..      12      92 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 6.8e-05
                EEEE-SSHHHHHHHHHHHHTT--EEEEES-GGGTT--SSSSEEE-T...THHHHHHHHHHHT.-SHHHHHHHHE CS
        GIDA  2 viViGgGhAGceAAlaaarlGakvlLithkldtiaelsCnpsiggi...akgllvrEidalg.gliikaadkag 71
                v ++GgG  G+  A+ + r++++v+++ +  + ++e++   sig     a  l+  +i+ ++ +li + ad+ g
  EEA20252.1 13 VAIVGGGIGGLTLAIGLLRRNVSVAIY-EAASAFGEVGLGLSIGPAahrAMPLIDPQIRDIYdSLITTHADSEG 85
                89*************************.9999999999999999887778888888888876688888888765 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   0.00011      0.15      19      55 ..      12      47 ..       6      86 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00011
                EEEEE--SHHHHHHHHHHHHCTTS-EEEEESSSS--T CS
        Thi4 19 DvvivGaGssGLtaayylakkpdlkvailersvspGG 55
                 v+ivG+G  GLt a  l ++ ++ vai e+  ++G 
  EEA20252.1 12 TVAIVGGGIGGLTLAIGLLRR-NVSVAIYEAASAFGE 47
                589*****************9.**********99984 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.9   0.00012      0.16       2      37 ..      12      47 ..      11      48 .. 0.95

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00012
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SSSSS-H CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVlllekakklgr 37
                 +v+++GgG  Gl  Ai + +r+ +V+++e+a+++g+
   EEA20252.1 12 TVAIVGGGIGGLTLAIGLLRRNVSVAIYEAASAFGE 47
                 79*****************************99985 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   1.8      0.03        38       2      47 ..      13      56 ..      12      66 .. 0.79
   2 ?    6.2   0.0     0.003       3.9     169     225 ..     138     192 ..     123     199 .. 0.77
   3 ?   -1.4   0.0      0.63   8.1e+02     316     358 ..     307     350 ..     283     372 .. 0.70

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.03
                    EEEE--SHHHHHHHHHHHHHTTTSSEEEEEE-S.SS---SS-EE--T CS
  Trp_halogenase  2 ivivGGGtaGwlaAaalakalkgklevtlvese.eigtvgvGeatip 47
                    + ivGGG+ G + A+ l +     ++v + e++ ++g vg G +  p
      EEA20252.1 13 VAIVGGGIGGLTLAIGLLRRN---VSVAIYEAAsAFGEVGLGLSIGP 56
                    89*************998877...78888886526788888877655 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.003
                     -EEEE--EEEEEE-TTS-EEEEEETTS-EEE-SEEEE-SGGG-IIIIIIT---EEE- CS
  Trp_halogenase 169 vtrvegkvvevqldedgrveslrledgreveadlfiDcsGfrgllieqaLktgfedw 225
                     v +   + v+ + ++ g    l  edg+++ ad ++ c G r+++ e+ +  ++e++
      EEA20252.1 138 VAQFGKRLVKLKEEPAG--VTLSFEDGTSIVADVVVGCDGIRSRVKESLFPDEVEQF 192
                     55555555555555544..368899********************999887777766 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.63
                     TTEEE-CCCTEE--CCCS-HHHHHHHHHHHHHHT--BTT--.HH CS
  Trp_halogenase 316 knvvalGlasgfvePlestsihliqaalrrLlallpdksde.pa 358
                       v  lG+a+ +  P ++++   + ++++ L++ll+dk +  p 
      EEA20252.1 307 SKVAILGDAAHASTPHQGAGAGQAIEDAHVLAELLADKRVTtPE 350
                     45556788888888888888888888888888888887655333 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   1.8    0.0014       1.8       2      35 ..      13      46 ..      12      62 .. 0.89

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0014
                EEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSS CS
   Pyr_redox  2 vvvvGgGyiglElAgalaelgkkVtvversdkll 35
                v++vGgG  gl lA  l + + +V + e+++ + 
  EEA20252.1 13 VAIVGGGIGGLTLAIGLLRRNVSVAIYEAASAFG 46
                89***********************999988776 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   1.1      0.02        25       2      32 ..      13      41 ..      12      46 .. 0.85
   2 ?    4.0   0.0     0.017        22      82     145 ..     119     180 ..      79     209 .. 0.83
   3 ?   -0.1   0.2      0.29   3.8e+02     255     298 ..     306     349 ..     290     378 .. 0.67

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.02
  Lycopene_cycl  2 vvviGaGpAglslAarlteakpglkvvliea 32
                   v+++G+G  gl lA  l   + +++v + ea
     EEA20252.1 13 VAIVGGGIGGLTLAIGL--LRRNVSVAIYEA 41
                   89*************99..778888887776 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.017
  Lycopene_cycl  82 grvsskrlkeellerlvengvklleakvesveeeeageslvvleggrkirarlvvdarglaslk 145
                     +v+++++ + l + ++ +gv     +  + +ee+a  ++   e+g  i a +vv   g+ s+ 
     EEA20252.1 119 TTVRRSDFLNALVNLVP-DGVAQFGKRLVKLKEEPA-GVTLSFEDGTSIVADVVVGCDGIRSRV 180
                    57899999988887766.788888888999999999.8999***************99977766 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.29
  Lycopene_cycl 255 eqkvlaiGaaaglvhPaTGYsvarslaeapllasaiaaalress 298
                    ++kv+ +G aa +  P  G    +++  a +la+ +a+   +  
     EEA20252.1 306 KSKVAILGDAAHASTPHQGAGAGQAIEDAHVLAELLADKRVTTP 349
                    45577789999999999999888999999888888777655432 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (432 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       397  (0.0221429); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.45
# Mc/sec: 2854.43
//
Query:       EEA20253.1  [L=385]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (385 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       749  (0.0417759); expected 358.6 (0.02)
Passed bias filter:                      310  (0.0172904); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.52u 0.30s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 2630.99
//
Query:       EEA20254.1  [L=525]
Description: polyamine transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-14   53.9  40.8    1.4e-14   53.9  40.8    1.8  1  MFS_1     Major Facilitator Superfamily
    6.1e-07   28.7  12.2    6.1e-07   28.7  12.2    2.7  2  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.9  40.8   1.5e-18   1.4e-14       3     316 ..      60     421 ..      58     461 .. 0.70

  Alignments for each domain:
  == domain 1  score: 53.9 bits;  conditional E-value: 1.5e-18
       MFS_1   3 laaflsalarsi..lgpalplalaedlgispseigllltl.yalgaavaslpl.GrlsdrfGrrrvlllglllfalglllll.fa.sslw.lllvlrvl 94 
                  +++l+a+a+ +   + +l+ ++++   ++++   ll+++  +l+ +va +++  +l+  +Gr +v++++l++ ++g ++++ ++  + + ++ ++r++
  EEA20254.1  60 ASVCLAAFAAQMspNSNMLT-FMSQVPAYNKTPNDLLYSVsAGLAGWVAGPFFfIPLVGVVGRGSVIFWSLVCIFAGQIWGAeMTgVNDYiPFTISRLF 157
                 55666666666643333333.6666544555555554444323333333333336666667****************888888867777779******* PP

       MFS_1  95 qGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee..... 188
                 +Gl++g+ + +g  +i d+f   +rg+a++++ +++ ++++ g  lgg++a +  W +vf+   +    a++l+++++  e+++  r+++++       
  EEA20254.1 158 TGLFGGIPAILGSGYIIDMFFLHQRGKAFAVFEIMIIFAVVGGGTLGGFIANNNPWDLVFWWTLGPVGAAMILVFVFV--EETTYNRDADVPHPplpkt 254
                 ***********************************************************9888888888878755666..3333333333333333666 PP

       MFS_1 189 .....................kgtgpaplvpawkallkdpvlw...illialllfffgfsg..lltllplylqevlglsglllaglllallalvgaila 261
                                      k  ++++++p +++ +++  l+   ++++al l  +  s+  +++  p  +   +g+s  l+++++ + +++++a+++
  EEA20254.1 255 wlanrvatffpgtktqpagkgKEFVRRAITP-FQITFAPITLLmgtYIFVALGLPIMQASTlaTFMEPP-VVAGGYGFS-SLQMAFFTMTAWVGIACAQ 350
                 7778888899777777777766667777777.7777777766555333333333333333353333334.57*******.6888877777777777776 PP

       MFS_1 262 llagrls.dr............lgrrrrlllallllllaalglallavtssavllllvlvl....iGfglgf 316
                  + g++  d             + ++ rl  ++l  +++ +gl l+++   ++l+++vl+l    i fg+ +
  EEA20254.1 351 -IYGFFFnDTtplwvarrrggtWHPEYRLANTILPSIMLPIGLGLWGAGLQYHLHYMVLALgsflIWFGALL 421
                 .444444377888888899999999************************99999999888833323332222 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.7  12.2   6.8e-11   6.1e-07      24     194 ..      76     238 ..      53     243 .. 0.86
   2 ?   -6.9   8.6         2   1.8e+04     101     186 ..     404     489 ..     384     494 .. 0.61

  Alignments for each domain:
  == domain 1  score: 28.7 bits;  conditional E-value: 6.8e-11
                 HHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHH CS
    Sugar_tr  24 tllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvl 122
                 ++l f ++  +++++   +    ++  +vs+ l+G ++G +f+ +l+ ++GR +++  + v+ ++g++  a  +g n +  ++++R+++G++ G+  +l
  EEA20254.1  76 NMLTFMSQVPAYNKT--PN----DLLYSVSAGLAGWVAGPFFFIPLVGVVGRGSVIFWSLVCIFAGQIWGAEMTGVNDYIPFTISRLFTGLFGGIPAIL 168
                 444433333333333..33....46899**********************************************99*********************** PP

                 HHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHH.HHHHHHHGGGS--- CS
    Sugar_tr 123 vPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvp.allllilllflPES 194
                  + yi  +   + Rg+   +++ +i+f  + + ++g ++++++    w + ++ +l p   +++++++f++E+
  EEA20254.1 169 GSGYIIDMFFLHQRGKAFAVFEIMIIFAVVGGGTLGGFIANNNP---WDLVFWWTLGPvGAAMILVFVFVEET 238
                 ********************************999999999999...******999873457888889**999 PP

  == domain 2  score: -6.9 bits;  conditional E-value: 2
                 S-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHH CS
    Sugar_tr 101 svevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpalllli 186
                 ++ vl++g +l+ +g+ la  ++  yi E    +   a vsl+   itfG +  +i++   + ++  + w +  +l ++  l+++ 
  EEA20254.1 404 HYMVLALGSFLIWFGALLALPVCYNYIIECFLHTPVEASVSLNAYRITFGLISVFITTNWEAAVGVGWMWGMGSFLIVFVDLIMIG 489
                 46667777777777777777777777777777777777788888888888655544433333333335555555555555544444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (525 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       634  (0.0353617); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.32s 00:00:00.96 Elapsed: 00:00:00.52
# Mc/sec: 3017.11
//
Query:       EEA20255.1  [L=521]
Description: hypothetical protein PMAA_041140 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-14   54.6   3.0      2e-12   47.7   0.1    2.4  2  HET       Heterokaryon incompatibility protein (HET)


Domain annotation for each model (and alignments):
>> HET  Heterokaryon incompatibility protein (HET)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.7   0.1   1.1e-16     2e-12       1      85 [.      66     162 ..      66     170 .. 0.81
   2 !    7.6   0.4   0.00025       4.5     133     146 .]     169     182 ..     161     182 .. 0.85

  Alignments for each domain:
  == domain 1  score: 47.7 bits;  conditional E-value: 1.1e-16
         HET   1 YeaLSYvWgdsk..........ekeeievng...klleltenledalqvlrklgerylWiDaiCInQdddkekskqvqlmadIYsnAelvivalgses 85 
                 Y+++S+ W  s+          +  +i++++   +++++ e l +a + +r+lg  + W D  C++Qd++++k+ q+q+m+++Y+++++viv+ g+  
  EEA20255.1  66 YATISHSWAASDevqrlseiadRPLRIDLGNnkyHTISW-EGLVQAAKAARHLGCVFFWLDLTCVHQDSSDDKKLQIQHMGHVYQKSAAVIVMPGGVA 162
                 99******9888677777776545556665565444444.557788899*******************************************988765 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.00025
         HET 133 lespwfkRvWvlQE 146
                  ++pw +R+W+lQE
  EEA20255.1 169 YSAPWITRAWTLQE 182
                 579**********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (521 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       432  (0.024095); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.26s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 3316.47
//
Query:       EEA20256.1  [L=210]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.25   11.4   1.2       0.37   10.8   1.2    1.2  1  RTX_C     RTX C-terminal domain


Domain annotation for each model (and alignments):
>> RTX_C  RTX C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   1.2   2.1e-05      0.37     114     152 ..      37      78 ..      19      84 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 2.1e-05
       RTX_C 114 ynll.kqkknlsndieklisst..saftssskalsaspldir 152
                 yn + +++k l+  ++++isst  +++ts s al++sp   +
  EEA20256.1  37 YNCScRNNKPLNTTVSRMISSTqrATYTSTSSALASSPFRLN 78 
                 454414567899*********9555899**********8765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (210 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1033  (0.0576162); expected 358.6 (0.02)
Passed bias filter:                      626  (0.0349155); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 1405.09
//
Query:       EEA20257.1  [L=417]
Description: 3-ketoacyl-coA thiolase peroxisomal A precursor [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.7e-76  255.1   1.0    6.7e-76  255.1   1.0    1.5  2  Thiolase_N     Thiolase, N-terminal domain
    6.1e-44  148.6   0.2    1.4e-43  147.5   0.2    1.6  1  Thiolase_C     Thiolase, C-terminal domain
     0.0076   15.9   1.8      0.041   13.4   0.6    2.6  2  ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
  ------ inclusion threshold ------
        0.1   12.9   0.1       0.21   11.9   0.1    1.6  1  Cadherin_tail  Cadherin C-terminal cytoplasmic tail, catenin-
       0.11   12.3   1.0         17    5.4   0.0    2.6  2  ACP_syn_III    3-Oxoacyl-[acyl-carrier-protein (ACP)] synthas


Domain annotation for each model (and alignments):
>> Thiolase_N  Thiolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  255.1   1.0   1.9e-79   6.7e-76       1     260 []      32     287 ..      32     287 .. 0.97
   2 ?   -3.0   0.0         1   3.7e+03      31      46 ..     321     336 ..     319     341 .. 0.83

  Alignments for each domain:
  == domain 1  score: 255.1 bits;  conditional E-value: 1.9e-79
                 EEEEEEEEE--EE.TTSTTTTS-HHHHHHHHHHHHHHHHTS-GGGCCEEEEEHSSCTTSTSCHHHHHHHHTTS-TTSEEEEEEHGGGHHHHHHHHHHHH CS
  Thiolase_N   1 vvivsaartpigk.fggslkdlsaeeLlaealkallekagvdpeevdevivGnvlqagegqniarqaalkagipeevpavtvnkvcsSglkavalaaqs 98 
                 +v+ +a rtp++k  +g +kd+ a +Ll  a ++l+++ g+dp+ v++++vG vl  g g+++ r+aal ag+pe++++  +n++csSgl+av+++a++
  EEA20257.1  32 IVVTAALRTPFTKgGKGGFKDTAAADLLVGAFQGLIKRSGIDPKLVEDIAVGSVLPPGGGATEFRAAALVAGFPESTAVRSLNRQCSSGLQAVTDIANA 130
                 6999*********99************************************************************************************ PP

                 HHTTSHSEEEEEEEEESTTS-EEETCTTTTGGSSSSEEEEEHHHHHHTEETTTTSEHHHHHHHHHHHHT--HHHHHHHHHHHHHHHHHHHHTTTTTTTB CS
  Thiolase_N  99 iaageadvvvagGvEsmsnaptaestdvrsglklgdekakdllipdgladafneehmGltaenlakkykisReeqdefAvkshqkaaaaqkagkFkdei 197
                 i+ag+++v v  GvEsms ++   +++  s l  ++ +a ++ +p+           G+ +en+ak+ +isR+eqd+fA++s+qka +aqkag F++ei
  EEA20257.1 131 IRAGQIEVGVGAGVESMSLQYGPGAVTEFSDLLENHMQAANCKVPM-----------GVLSENMAKDRNISRTEQDAFAASSYQKAIKAQKAGLFDEEI 218
                 *************************9999*************9988...........****************************************** PP

                 E-EEEEESSSEE......EE-S-TTS-TT--HHHHHTS-BSSSTTSS-BTTSB--BEEEEEEEEEEEHH CS
  Thiolase_N 198 vPvkvkgkkgkk......tvdkdeairsevtaekLaklkpaFkkeGtvtAgnasqisDGaaavllmses 260
                  P++vk  + k+      tv++d+++r+++t e+Lak+kpaF k+G+++Agnasq+sDGaaavllm++s
  EEA20257.1 219 YPLTVKWTDPKTgdektiTVKADDGVREGITPESLAKIKPAFAKDGSIHAGNASQVSDGAAAVLLMKRS 287
                 ****99888775567888************************************************985 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1
                 HHHHHHHHTS-GGGCC CS
  Thiolase_N  31 lkallekagvdpeevd 46 
                 +  +lekag+++++vd
  EEA20257.1 321 IPVALEKAGISKDDVD 336
                 6678999***999998 PP

>> Thiolase_C  Thiolase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  147.5   0.2   3.9e-47   1.4e-43       2     120 ..     295     413 ..     294     416 .. 0.97

  Alignments for each domain:
  == domain 1  score: 147.5 bits;  conditional E-value: 3.9e-47
                 --SEEEEEEEEEE--GGGGGGHHHHHHHHHHHHHT--GGGESEEEE--SBHHHHHHHHHHHT--GGGBSTT--HHHH-B-TTTHHHHHHHHHHHHHHHC CS
  Thiolase_C   2 kplakirsyaevgvdpeilglgPayaikkvlkkagltvedidlfEinEAFaaqaLavakaldldlekvNvnGGaialGHPlGasGaRivvtllselkke 100
                 k+++k+++ + vgv+p  +g+gP  ai+ +l+kag++ +d+d++EinEAFa+q++ ++k+l+l  ekvN +GGaia GHPlG++GaR+v tl +elk+ 
  EEA20257.1 295 KIIGKFVTASIVGVEPLLMGIGPWKAIPVALEKAGISKDDVDIYEINEAFASQCVWCVKELGLPFEKVNPKGGAIAFGHPLGCTGARQVSTLFTELKRT 393
                 67788999999**************************************************************************************** PP

                 TTSEEEEEEEETTTEEEEEE CS
  Thiolase_C 101 ggklgvaalCigggqgvalv 120
                 ++k+gv+++Cig+g+g+a+v
  EEA20257.1 394 NKKIGVTSMCIGTGMGMAAV 413
                 *****************987 PP

>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.6   1.2e-05     0.041     174     209 ..     116     151 ..      97     174 .. 0.81
   2 ?    0.0   0.0      0.14   5.1e+02     234     253 .]     270     289 ..     251     289 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 1.2e-05
                    GGGHHHHHHHHHHHHHHTTS-SEEEEEEEE---SHH CS
  ketoacyl-synt 174 ACsSslvavhaavqslrsgeadvalaGGvellltpe 209
                     CsS+l av  + +++r+g+++v +  Gve +  + 
     EEA20257.1 116 QCSSGLQAVTDIANAIRAGQIEVGVGAGVESMSLQY 151
                    5****99999999****************9886544 PP

  == domain 2  score: 0.0 bits;  conditional E-value: 0.14
                    -SB-BB-EEEEEEEEECHHH CS
  ketoacyl-synt 234 dGfvlGEGvGavvLkrleda 253
                    +   +++G++av+L+++++a
     EEA20257.1 270 NASQVSDGAAAVLLMKRSTA 289
                    666789********999876 PP

>> Cadherin_tail  Cadherin C-terminal cytoplasmic tail, catenin-binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.1     6e-05      0.21      43      77 ..     124     156 ..      90     213 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 6e-05
  Cadherin_tail  43 vssaaaenevgevspplGaGvnsnslsfrygpgnt 77 
                    v+ +a++ ++g +   +GaGv+s+sl  +ygpg  
     EEA20257.1 124 VTDIANAIRAGQIEVGVGAGVESMSL--QYGPGAV 156
                    33489999************999987..6888864 PP

>> ACP_syn_III  3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.2    0.0072        26       3      38 ..     113     148 ..     112     151 .. 0.87
   2 ?    5.4   0.0    0.0047        17      51      65 ..     273     287 ..     263     302 .. 0.76

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0072
                  EE-GGGHHHHHHHHHHHHHHTTS-SEEEEEEEEEGG CS
  ACP_syn_III   3 lnaaCsgfvyalsvAdaliesgaakrvLvigaetls 38 
                  ln +Cs+ ++a+   +++i++g+++  +  g e +s
   EEA20257.1 113 LNRQCSSGLQAVTDIANAIRAGQIEVGVGAGVESMS 148
                  6889*******************9987777777776 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.0047
                  TB-EEEEEEEEEEES CS
  ACP_syn_III  51 lfGDGAgAvvlease 65 
                   ++DGA+Av+l +  
   EEA20257.1 273 QVSDGAAAVLLMKRS 287
                  579********9873 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (417 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       577  (0.0321825); expected 358.6 (0.02)
Passed bias filter:                      505  (0.0281667); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 2786.48
//
Query:       EEA20258.1  [L=1963]
Description: proteasome activator subunit 4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
     4e-213  708.8   0.0   7.6e-213  707.9   0.0    1.5  1  BLM10_mid  Proteasome-substrate-size regulator, mid region
      3e-30  104.0   0.0    3.4e-29  100.6   0.0    2.8  3  DUF3437    Domain of unknown function (DUF3437)
    1.5e-20   73.3   0.1    6.1e-20   71.3   0.0    2.1  2  BLM10_N    Proteasome-substrate-size regulator, N-terminal
     0.0023   17.5   1.0          2    7.9   0.0    4.0  4  CLASP_N    CLASP N terminal
  ------ inclusion threshold ------
      0.012   15.8   0.1         13    6.4   0.0    4.9  5  HEAT       HEAT repeat
      0.046   14.2   0.0         35    5.1   0.0    4.4  3  HEAT_EZ    HEAT-like repeat


Domain annotation for each model (and alignments):
>> BLM10_mid  Proteasome-substrate-size regulator, mid region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  707.9   0.0  2.5e-216  7.6e-213       1     524 []     377     904 ..     377     904 .. 0.99

  Alignments for each domain:
  == domain 1  score: 707.9 bits;  conditional E-value: 2.5e-216
   BLM10_mid   1 LekLiksietffHPSnsGswtkplskfvkelikeflkRwneEekkecktpeerrLteeikkefVkiLrtvvllgifskdskvanyaqsaLklLalLePd 99 
                 Le+Li+++etffHPSnsG+wtk+l+++v++l+++f++Rwn+E+++e+++p+er+L+e +kk+fV +Lr+v+++gi++k+ +++n+++s+L++La+LeP+
  EEA20258.1 377 LEGLIQAVETFFHPSNSGNWTKTLAQLVYYLSDFFIMRWNREHNGEMEVPPERKLNEPLKKRFVLCLRDVIFMGIYAKSGTAMNFSLSTLQSLAYLEPQ 475
                 899************************************************************************************************ PP

   BLM10_mid 100 lilpkiLeriypsLeglnethRtiasLkalttlarvlvstklyrvhltplLslllpgIDlNDlekTlntlnfivsvaqfipiedltkeeeelsdeslal 198
                 lilp++L+riyps++gl+e+hRt++sL++l+ l+r++++tk +r+h+t+lL l+lpgID+NDlek++++l+fi+sv+++ip+edltk +++++ ++la+
  EEA20258.1 476 LILPGALQRIYPSMQGLVEVHRTTSSLRSLQVLSRIIARTKGFRCHMTTLLGLALPGIDPNDLEKSMHALSFIQSVCYNIPFEDLTKGRDDVNCNMLAM 574
                 *************************************************************************************************** PP

   BLM10_mid 199 efiqqevekleekkeeeeeeeefeldkeeeeaalrsStaaFeewvksfldrvftLlenlPeeskkksgklEesvvnklpatldilleslsdelfdlalk 297
                 ++i+ eve++e ++++++ +++++l++e+ee++lrsSt++F e+++sfl+rvftLlenlP++s++ksg++Ee+vvn+lpatl++ll++ls+el+d+al+
  EEA20258.1 575 QWITGEVERMEVEGANVQLNYDTDLSDETEEMILRSSTTGFGEFLISFLGRVFTLLENLPDASRVKSGSPEENVVNTLPATLMPLLSALSPELYDMALQ 673
                 *************************************************************************************************** PP

   BLM10_mid 298 kvvdfvsnnvksnavdavaellaalvkanpektlkkllpllienIreei.engAgsvr.ttseilprDraLvwnlsiLnevvrnagealLkykdellel 394
                 kvvdfvsn+v+++a+da+a++++a++k+npek+lk+++plli+ Ir+ei engA+s+r t+se+lprDraLvwn+s+L+++v+++g+a+L++k+ell++
  EEA20258.1 674 KVVDFVSNHVIHQARDAMAFICNAVCKVNPEKALKRFVPLLIQGIRSEIdENGAASTRtTGSEVLPRDRALVWNVSMLSMCVVHVGSAVLNHKQELLDI 772
                 **********************************************************99999************************************ PP

   BLM10_mid 395 lklllekcksergyvltsklvhslLltLtktyptesrlvnpeeekseelkeehWGklqedenlkikWhvPseeeidfAvelleeivepalkklekllee 493
                 + +++ekck+ + ++++s+++h+lLl+Lt ty++++ l++ e  k+  +k ehWG   +++nl+i+WhvP+++ei+fAv l+++++e+al++l++l++ 
  EEA20258.1 773 AIYMQEKCKGIP-TIHVSNFIHHLLLNLTVTYTLDYGLFELEDIKDG-IKIEHWGYCPDPQNLNINWHVPNRQEIEFAVALFQSQAESALSQLTALTDG 869
                 ************.******************************9776.*************************************************** PP

   BLM10_mid 494 ek....skkdkewsdelcryllllrlalsGislLf 524
                 ++    + + kewsde++r l+llrl++sGis+Lf
  EEA20258.1 870 TSsvkrDGSGKEWSDEVTRKLVLLRLIISGISVLF 904
                 99999999**************************8 PP

>> DUF3437  Domain of unknown function (DUF3437)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   0.0       5.7   1.7e+04      26      45 ..    1121    1142 ..    1120    1147 .. 0.73
   2 ?   -1.1   0.0      0.61   1.8e+03      28      73 ..    1585    1631 ..    1583    1643 .. 0.80
   3 !  100.6   0.0   1.1e-32   3.4e-29       3      88 .]    1876    1963 .]    1874    1963 .] 0.93

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 5.7
     DUF3437   26 lpevleeLar..aardpapirk 45  
                  +p++l++L +  +++d a i+ 
  EEA20258.1 1121 IPPLLQALQKaiKENDHARIKG 1142
                  8999999999655666656665 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.61
     DUF3437   28 evleeLaraardpa.pirktvkktlseFkrthqDtWeedkkkFteeq 73  
                  +++e+++++  +p   +r+++ +tl++  rt+  + + d +++ e+q
  EEA20258.1 1585 PIVEDFVSHLDHPYkGVREAMGHTLGSIFRTRYHESHADVDSLIEAQ 1631
                  5677888888898866***********99999888888888877776 PP

  == domain 3  score: 100.6 bits;  conditional E-value: 1.1e-32
     DUF3437    3 erhaavlglsAlvlafpydvP..kwlpevleeLar.aardpapirktvkktlseFkrthqDtWeedkkkFteeqledledvllspsYya 88  
                   rhaavlgl+Alv+afpy +P   w+p++l++L++ aa+dp  ++++vk+++seFk+t+qDtW+ d+k+Ft++qledl++v l++sY+a
  EEA20258.1 1876 IRHAAVLGLGALVQAFPYASPppYWMPDALTTLSTkAAHDPGVVGSSVKSIISEFKKTRQDTWHIDQKAFTSDQLEDLSGV-LWKSYFA 1963
                  69*****************99889**********94555555***************************************.******7 PP

>> BLM10_N  Proteasome-substrate-size regulator, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.3   0.0     2e-23   6.1e-20       3      81 .]      22      89 ..      20      89 .. 0.91
   2 ?   -2.3   0.0       1.8   5.5e+03      47      65 ..    1736    1754 ..    1727    1754 .. 0.75

  Alignments for each domain:
  == domain 1  score: 71.3 bits;  conditional E-value: 2e-23
     BLM10_N  3 eeisratsygldypedeeellkeiedkkskffaRsrprtfpyeklLPYkvEsekerakyLshilknLYiAikslDiqgg 81
                +eisrats+g++ +e++         +k+   aR rprt+py+++LPY++E++++r+++L++il+ LY+Aik++D+++g
  EEA20258.1 22 HEISRATSPGGEPVEADG--------SKK---ARVRPRTYPYFSYLPYQTEDDSQREENLHEILSCLYVAIKAGDFSPG 89
                789************432........334...9********************************************96 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1.8
     BLM10_N   47 lLPYkvEsekerakyLshi 65  
                   +PY++E+e+   + L hi
  EEA20258.1 1736 NIPYPAENESSFIETLVHI 1754
                  469****999888888876 PP

>> CLASP_N  CLASP N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.9   0.0   0.00067         2      43     139 ..     435     530 ..     428     549 .. 0.87
   2 ?   -0.4   0.1      0.24   7.2e+02     123     179 ..    1158    1215 ..    1153    1258 .. 0.77
   3 ?   -0.8   0.1      0.31   9.3e+02      15      75 ..    1217    1276 ..    1205    1288 .. 0.81
   4 !    4.3   0.0    0.0085        25     175     214 ..    1788    1827 ..    1670    1841 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.00067
     CLASP_N  43 aveelleclkqlleailkalssLrttlsstgchllkelaiqlkeq.ldpmveillptLlkllgdtKkiisqnanqalaallsnas.fsprilqvlsval 139
                   + ++ cl+   + i+  + + + t ++ ++++l+ la  + +  l   +++++p++  l+  +   +s  + q+l+ +++ ++ f +++ ++l +al
  EEA20258.1 435 LKKRFVLCLR---DVIFMGIYAKSGTAMNFSLSTLQSLAYLEPQLiLPGALQRIYPSMQGLVEVHRTTSSLRSLQVLSRIIARTKgFRCHMTTLLGLAL 530
                 5678999***...********************************66666********************************99877777777777666 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.24
     CLASP_N  123 snasfspri.lqvlsvalqdKnvqpReysaiwLkilltrfeshkskleasllldliek 179 
                  ++ +++p++   ++ + ++dK   ++++s    +i+    + +++++ +++l+d+i +
  EEA20258.1 1158 RHWKYTPDVvRAFIDASSVDKPSVQKLCSGAIYQIMEYGRPLERMAVLNEELVDSIAP 1215
                  5678889998999999999999999999999999998888877777777777777766 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 0.31
     CLASP_N   15 ketelnwdaReknilklrslikgnvpedaveelleclkqlleailkalssLrttlsstgch 75  
                   ++e  + ++ ++i k r  i+g+ + +  eel+e+ +++   i++ ++s+  ++    +h
  EEA20258.1 1217 ENVEDTITQKRNSISKKRVQIEGK-KAELAEELVEMAQTSHWKIASRAASIVVSMGLRFGH 1276
                  5899999*****************.999999*****9999999999999887776666555 PP

  == domain 4  score: 4.3 bits;  conditional E-value: 0.0085
     CLASP_N  175 dliekslkkgleDanptVRetaRstfweffkvwPsrAksl 214 
                  d + +++  +l+D++ +VR  a +t+  + ++ P   ++ 
  EEA20258.1 1788 DKLFECVANMLQDSQHEVRVGASATLSGMIRCSPVALREA 1827
                  44568999*********************99999766555 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0       1.5   4.5e+03       5      29 ..    1170    1194 ..    1166    1195 .. 0.78
   2 ?   -2.8   0.0         4   1.2e+04      16      30 ..    1474    1488 ..    1467    1489 .. 0.78
   3 ?   -1.4   0.0       1.4   4.2e+03       5      27 ..    1590    1612 ..    1586    1614 .. 0.84
   4 ?    6.4   0.0    0.0042        13       1      28 [.    1790    1817 ..    1790    1820 .. 0.87
   5 ?    2.4   0.1     0.081   2.4e+02      16      29 ..    1876    1889 ..    1874    1891 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 1.5
                  HHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT    5 llkllsDpspeVReaAakaLgalae 29  
                  ++ + s + p+V + +  a+ +++e
  EEA20258.1 1170 FIDASSVDKPSVQKLCSGAIYQIME 1194
                  55555667899***********998 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 4
                  HHHHHHHHHHHHHHC CS
        HEAT   16 VReaAakaLgalaev 30  
                  + +a+a+ Lgal++ 
  EEA20258.1 1474 QHRATAEILGALISS 1488
                  56899******9875 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 1.4
                  HHHHHT-SSHHHHHHHHHHHHHH CS
        HEAT    5 llkllsDpspeVReaAakaLgal 27  
                  +++ l +p   VRea   +Lg +
  EEA20258.1 1590 FVSHLDHPYKGVREAMGHTLGSI 1612
                  67789999999****99999987 PP

  == domain 4  score: 6.4 bits;  conditional E-value: 0.0042
                  HHHHHHHHHT-SSHHHHHHHHHHHHHHH CS
        HEAT    1 llPlllkllsDpspeVReaAakaLgala 28  
                  l+ ++ ++l+D+  eVR  A  +L  ++
  EEA20258.1 1790 LFECVANMLQDSQHEVRVGASATLSGMI 1817
                  567999**************99998776 PP

  == domain 5  score: 2.4 bits;  conditional E-value: 0.081
                  HHHHHHHHHHHHHH CS
        HEAT   16 VReaAakaLgalae 29  
                  +R aA++ Lgal++
  EEA20258.1 1876 IRHAAVLGLGALVQ 1889
                  7***********98 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.16   4.9e+02      25      55 .]    1162    1192 ..    1158    1192 .. 0.90
   2 ?    5.1   0.0     0.012        35      28      53 ..    1789    1814 ..    1787    1814 .. 0.90
   3 ?    1.2   0.0      0.19   5.5e+02       3      20 ..    1876    1892 ..    1875    1908 .. 0.77

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.16
     HEAT_EZ   25 lvpeilpaLlalLnddsdeVRaaAagaLgnl 55  
                  + p++++a++ + + d+++V++ + ga+ ++
  EEA20258.1 1162 YTPDVVRAFIDASSVDKPSVQKLCSGAIYQI 1192
                  679999999988888************9987 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.012
     HEAT_EZ   28 eilpaLlalLnddsdeVRaaAagaLg 53  
                  ++  + +++L+d++ eVR  A  +L+
  EEA20258.1 1789 KLFECVANMLQDSQHEVRVGASATLS 1814
                  577899***************99986 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.19
     HEAT_EZ    3 vRraAawaLGrlaggepe 20  
                  +R+aA+++LG+l + +++
  EEA20258.1 1876 IRHAAVLGLGALVQ-AFP 1892
                  69********9774.444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1963 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       596  (0.0332422); expected 358.6 (0.02)
Passed bias filter:                      544  (0.0303419); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.13u 0.29s 00:00:01.42 Elapsed: 00:00:00.46
# Mc/sec: 12691.74
//
Query:       EEA20259.1  [L=474]
Description: DUF409 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.6e-52  178.6  17.2    3.3e-52  178.3  17.2    1.1  1  Mannosyl_trans2  Mannosyltransferase (PIG-V)
  ------ inclusion threshold ------
      0.096   12.3   0.7       0.42   10.3   0.3    2.2  2  HTH_50           Helix-turn-helix domain


Domain annotation for each model (and alignments):
>> Mannosyl_trans2  Mannosyltransferase (PIG-V)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  178.3  17.2   3.7e-56   3.3e-52      50     443 .]      88     474 .]      32     474 .] 0.82

  Alignments for each domain:
  == domain 1  score: 178.3 bits;  conditional E-value: 3.7e-56
  Mannosyl_trans2  50 lvekllenlvsWDsvyflkiaenGyeyeheyaflpllplfvsllskevlaplvgllslravlvlsvfslsillfllaavilsdvsvlvlkarea 143
                        +  ++n v WD++yf+++ae Gy++e+e+a+  +++  +s l  + +a   g + + a++  s++ ls l ++l+  il+ ++ l    ++ 
       EEA20259.1  88 SSSSGIWNFVRWDAIYFVRVAERGYLFEQEWAWGYGWTGLLSFLG-SAFANHNGDVPI-AAIAFSGIALSHLSHFLSSLILHALTKLLFGYETR 179
                      234559***********************************9998.999999999998.57899***********************9999998 PP

  Mannosyl_trans2 144 sfka.....sllfclspaavflasiYseaLfallafsgvyslesgi..............sissvllfalstivrsnglvsvgflmfsllqrff 218
                      s ka     + l ++spa  fl++ Y e+Lf ll f+g y   s+                  + +lfa +ti+r ng++s     +  +q++ 
       EEA20259.1 180 SQKAfclisAALHIISPAGAFLSAPYGESLFSLLNFTGFYIYSSALlvenagsrarrdiyFLLAGILFATATIIRGNGIISGCLFAYDAVQGVL 273
                      88874333366789**************************9999889999****9997766667789*************************99 PP

  Mannosyl_trans2 219 eaLielrkarkllkvliallLsvillflplvlfqyYaYkqfClqrsaGdevpWCksdvpllYsyiqshYWgvGlLkYyelkqvPnfLlaaPvli 312
                      + L +      l++   + +L +++++l  ++ qy aY+++C   ++    pWC   +p++Y ++q hYW+ G+L+Y+++ ++P f+laaPvl 
       EEA20259.1 274 QFLNNG-LSIDLIRRTGFIVLGGSIVALGSIIPQYIAYTEYCVATTR----PWCERLLPSVYGWVQVHYWNNGFLRYWTISNLPLFILAAPVLA 362
                      877654.5667899999****************************99....9****************************************** PP

  Mannosyl_trans2 313 lvvysilsyvksrpelflslGlqaseknkklekakdltylsadvfvlvvhaavlvviaflimhvqvltrflsasPllyWfaadllqktdlkkkk 406
                       ++ys++   + r     +  +  s+ n             + v+ l +   +l  ++   +hvq+++r++s  P+ yW++a     +   +++
       EEA20259.1 363 AMLYSSFRALTGRLGPSHTTHVSISKMNTS----------QSAVLRLAIAQGILAAMTLTSLHVQIINRIASGYPVWYWYLATSAWGS---TTQ 443
                      *****9999996655555555555555554..........345899999999999999999*******************99765533...344 PP

  Mannosyl_trans2 407 wkplaedkivklliyWkacaayilLgtlLfanflPft 443
                       + +    i       +  a+y l++ +L+ +flP++
       EEA20259.1 444 LGSR----IFTT--AVQGMAMYALIQAVLYGSFLPPA 474
                      4444....5444..4455569**************86 PP

>> HTH_50  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.3   4.6e-05      0.42      23      39 ..     366     382 ..     361     389 .. 0.92
   2 ?   -1.2   0.0      0.17   1.6e+03      33      42 ..     389     398 ..     387     400 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 4.6e-05
      HTH_50  23 YpStRklAkrLGvShta 39 
                 Y S+R l  rLG Sht+
  EEA20259.1 366 YSSFRALTGRLGPSHTT 382
                 9***************9 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.17
      HTH_50  33 LGvShtaian 42 
                 + +S++a+++
  EEA20259.1 389 MNTSQSAVLR 398
                 569*****97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (474 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       497  (0.0277205); expected 358.6 (0.02)
Passed bias filter:                      279  (0.0155614); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 3130.15
//
Query:       EEA20260.1  [L=338]
Description: DUF409 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.8e-32  112.6   7.9    3.1e-32  112.4   7.9    1.1  1  Mannosyl_trans2  Mannosyltransferase (PIG-V)
  ------ inclusion threshold ------
       0.23   11.0   0.0       0.33   10.5   0.0    1.2  1  AAA_27           AAA domain


Domain annotation for each model (and alignments):
>> Mannosyl_trans2  Mannosyltransferase (PIG-V)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.4   7.9   3.5e-36   3.1e-32      50     288 ..      88     338 .]      32     338 .] 0.83

  Alignments for each domain:
  == domain 1  score: 112.4 bits;  conditional E-value: 3.5e-36
  Mannosyl_trans2  50 lvekllenlvsWDsvyflkiaenGyeyeheyaflpllplfvsllskevlaplvgllslravlvlsvfslsillfllaavilsdvsvlvlkarea 143
                        +  ++n v WD++yf+++ae Gy++e+e+a+  +++  +s l  + +a   g + + a++  s++ ls l ++l+  il+ ++ l    ++ 
       EEA20260.1  88 SSSSGIWNFVRWDAIYFVRVAERGYLFEQEWAWGYGWTGLLSFLG-SAFANHNGDVPI-AAIAFSGIALSHLSHFLSSLILHALTKLLFGYETR 179
                      234559***********************************9998.999999999998.57899***********************9999998 PP

  Mannosyl_trans2 144 sfka.....sllfclspaavflasiYseaLfallafsgvyslesgi..............sissvllfalstivrsnglvsvgflmfsllqrff 218
                      s ka     + l ++spa  fl++ Y e+Lf ll f+g y   s+                  + +lfa +ti+r ng++s     +  +q++ 
       EEA20260.1 180 SQKAfclisAALHIISPAGAFLSAPYGESLFSLLNFTGFYIYSSALlvenagsrarrdiyFLLAGILFATATIIRGNGIISGCLFAYDAVQGVL 273
                      88874333366789**************************9999889999****9997766667789*************************99 PP

  Mannosyl_trans2 219 eaLielrkarkllkvliallLsvillflplvlfqyYaYkqfClqrsaGdevpWCksdvpllYsyiqshYW 288
                      + L +      l++   + +L +++++l  ++ qy aY+++C   ++    pWC   +p++Y ++q hYW
       EEA20260.1 274 QFLNNG-LSIDLIRRTGFIVLGGSIVALGSIIPQYIAYTEYCVATTR----PWCERLLPSVYGWVQVHYW 338
                      877654.5667899999****************************99....9****************** PP

>> AAA_27  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   3.7e-05      0.33      41      70 ..     164     193 ..     162     209 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 3.7e-05
      AAA_27  41 talrAisdllfGipertkdnflhdakkLri 70 
                  +l+A+++llfG ++r++++f      L i
  EEA20260.1 164 LILHALTKLLFGYETRSQKAFCLISAALHI 193
                 579******************988888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (338 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       487  (0.0271627); expected 358.6 (0.02)
Passed bias filter:                      315  (0.0175693); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.23s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 2482.00
//
Query:       EEA20261.1  [L=517]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (517 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       457  (0.0254894); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 3634.04
//
Query:       EEA20262.1  [L=208]
Description: carbonic anhydrase Nce103, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-41  142.4   0.0    1.7e-41  142.2   0.0    1.1  1  Pro_CA    Carbonic anhydrase


Domain annotation for each model (and alignments):
>> Pro_CA  Carbonic anhydrase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  142.2   0.0   9.2e-46   1.7e-41       1     155 [.      35     184 ..      35     185 .. 0.94

  Alignments for each domain:
  == domain 1  score: 142.2 bits;  conditional E-value: 9.2e-46
                 EEEEEETTTTS-HHHHTTS-TTSEEEEEETTG---TT-HHHHHHHHHHHHTS--SEEEEEEETT-HHHHHHHSHHCCSTTSSHHHHHHHHHHHHHHHCH CS
      Pro_CA   1 alvigCsDSRvppelitdagpGdlFvvrnvgnlvppadssvlaaleyAvevlkvkhivVlGHskCGavkaalkaekseeeagaidkwlekirealekve 99 
                 +l+igCsDSR+p+++i++ +pGd+Fv+rn++n++++ d s++ ++++Av +lkv++iv++GH++CG+v+aal +    ++ g +d+wl ++r+ ++++ 
  EEA20262.1  35 ILWIGCSDSRCPETTILGLQPGDVFVHRNIANIIHEGDLSSSCVIDFAVGALKVSQIVICGHTSCGGVNAALGD----SKLGVLDTWLLPLRKLRSRNL 129
                 59********************************999********************************99974....2379***************98 PP

                 HHHHTTSSHHHHHHHHHHHHHHHHHHHHHCSHHHHHHHHTTS-EEEEEEEETTTTE CS
      Pro_CA 100 eelesekekearerlleeenVaeqlenLlekpvvreavekgklkvhGlvydletGe 155
                  +le+ + k+a  +l +e+nV   + +++ek+vv ea+e++ lkv Gl+yd++tG 
  EEA20262.1 130 PTLEKLEPKNAIVKL-AELNVLDGMVKIKEKSVVLEAMEQRGLKVSGLIYDVATGL 184
                 888998888888887.**************************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (208 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       424  (0.0236488); expected 358.6 (0.02)
Passed bias filter:                      391  (0.0218082); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1450.80
//
Query:       EEA20263.1  [L=1571]
Description: hypothetical protein PMAA_041210 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00011   22.2   8.0    0.00046   20.2   8.0    2.1  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   8.0   2.6e-08   0.00046       1      35 [.       8      72 ..       8      77 .. 0.90

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 2.6e-08
                SS-HHHHHCT---ST.SSSS.............................-HHHHHCTHHHCCCCT CS
     Zn_clus  1 haCdnCrkkKvKCda.kkPa.............................CsnCkklnleCtfyse 35
                h+Cd+Cr+ ++ Cda k++                              Cs C+k n++C+f + 
  EEA20263.1  8 HSCDRCRQSRRACDAaKRGInpfsatnqqlpvllppggssgealpptlaCSLCEKANKKCSFTWL 72
                8**************96666666888889999*****************************9886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1571 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       622  (0.0346924); expected 358.6 (0.02)
Passed bias filter:                      429  (0.0239277); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.92u 0.31s 00:00:01.23 Elapsed: 00:00:00.48
# Mc/sec: 9941.01
//
Query:       EEA20264.1  [L=675]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.9e-17   61.0   0.5    1.3e-16   60.5   0.5    1.3  1  Fungal_trans    Fungal specific transcription factor domain
    3.7e-08   33.4  11.7    6.6e-08   32.6  11.7    1.4  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.012   14.1   0.4       0.02   13.4   0.4    1.2  1  Cep3            Centromere DNA-binding protein complex CBF3 s
        1.2    9.5  11.3        3.2    8.2  11.3    1.6  1  CENP-B_dimeris  Centromere protein B dimerisation domain
        9.8    5.2  10.5         22    4.0  10.5    1.5  1  DUF2457         Protein of unknown function (DUF2457)


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.5   0.5   3.6e-20   1.3e-16       3     200 ..     220     414 ..     218     520 .. 0.86

  Alignments for each domain:
  == domain 1  score: 60.5 bits;  conditional E-value: 3.6e-20
  Fungal_trans   3 rffsnfhpqfpilhkpsflpkt....ssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeili.hedfsspssslwil 94 
                   ++ +++   + +lh+ps+ +++     +  s++s++a+++l +a++  +  ++ + + ++ ++ +++      +  + e+ +  +d+   ++ +++l
    EEA20264.1 220 IYLDHVDRIIKVLHRPSLKRHFlegvPYPVSKSSREAENALDAAVFYAAVASMTDSQCYNLFQCSRNE-VLPEYQSACEMALeRADLMRTTD-MTVL 314
                   7999999999****************999999*********************************998.44433334444442556666666.**** PP

  Fungal_trans  95 qsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcdddd 191
                   q+++l+ +     ++ ++++ ++g+avr+a+ l Lh ++  +        +++++++r+Rlw+++  lD++++++    pl + ++++  LP + +d
    EEA20264.1 315 QAFVLYLVATRVHDKSRAVWTLLGTAVRVAQALNLHVESLGST------ETFFNQQMRKRLWFTICLLDVQTCFDADSRPLVPLEMTQPTLPLNVND 405
                   ***************************************9999......99999**************************99999999999999999 PP

  Fungal_trans 192 lwesddase 200
                    ++  + ++
    EEA20264.1 406 SDFDPSFDG 414
                   988877765 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.6  11.7   1.8e-11   6.6e-08       2      37 ..      23      57 ..      22      60 .. 0.93

  Alignments for each domain:
  == domain 1  score: 32.6 bits;  conditional E-value: 1.8e-11
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfysess 37
                +C+ Cr +K+KCd+  P C+ C+k +++C+ +++++
  EEA20264.1 23 SCEFCRHRKIKCDKLDP-CTACQKAGVKCESIRRKR 57
                8****************.************888875 PP

>> Cep3  Centromere DNA-binding protein complex CBF3 subunit B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.4   5.7e-06      0.02     112     205 ..     287     377 ..     258     384 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 5.7e-06
                 HHHHHHHHHHHHHHHHTTTTTS--HHHHHHHHHHTTTTHHHHSHHHHHHHHHHHHHHHHTT-----S--TTS-HHHHHHHHHHHHHHHHHHHHH CS
        Cep3 112 elyegflkttitqlkkanfmanpdirliQiyliLsnTsflfeensladslllqclhvaKlfkiddfkplvedsaalrlskltleklwyrlcilD 205
                 e++  ++ +  + l +a+ m++ d+ ++Q +++    + +++++  + +ll  +++va +++++     ++++     ++++ ++lw+ +c+lD
  EEA20264.1 287 EVLPEYQSACEMALERADLMRTTDMTVLQAFVLYLVATRVHDKSRAVWTLLGTAVRVAQALNLHVESLGSTETF---FNQQMRKRLWFTICLLD 377
                 5556666777789******************98777777888888899*************9998877666655...5778899********99 PP

>> CENP-B_dimeris  Centromere protein B dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2  11.3    0.0009       3.2       8      37 ..     153     182 ..     149     195 .. 0.72

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0009
  CENP-B_dimeris   8 agedsesesdeeeeeeeedeededeedded 37 
                     ag+d+e + d++++++e+d+ d+ + +de 
      EEA20264.1 153 AGDDTEGDGDDDDDDNEDDDHDDGDVEDER 182
                     688888888888888887777776666654 PP

>> DUF2457  Protein of unknown function (DUF2457)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0  10.5    0.0061        22      60      86 ..     155     182 ..     140     191 .. 0.46

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.0061
     DUF2457  60 deedeeddddddddedddeddde.eded 86 
                 d+ + + dddddd+eddd+dd + ede 
  EEA20264.1 155 DDTEGDGDDDDDDNEDDDHDDGDvEDER 182
                 2222222223333333333322213332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (675 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       880  (0.0490825); expected 358.6 (0.02)
Passed bias filter:                      633  (0.0353059); expected 358.6 (0.02)
Passed Vit filter:                        76  (0.00423894); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.71u 0.34s 00:00:01.05 Elapsed: 00:00:00.49
# Mc/sec: 4121.46
//
Query:       EEA20265.1  [L=328]
Description: developmental regulator VosA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-45  156.5   8.3      8e-33  114.4   0.3    2.6  3  Velvet    Velvet factor
  ------ inclusion threshold ------
      0.028   14.9   5.2       0.06   13.9   1.7    2.3  2  SPR1      Psoriasis susceptibility locus 2


Domain annotation for each model (and alignments):
>> Velvet  Velvet factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.5   0.1   1.2e-16   1.1e-12       1      69 [.       9      75 ..       9      83 .. 0.82
   2 !  114.4   0.3   8.9e-37     8e-33     140     249 ..      77     177 ..      71     179 .. 0.95
   3 ?   -1.7   0.4      0.25   2.2e+03     107     107 ..     240     240 ..     182     310 .. 0.49

  Alignments for each domain:
  == domain 1  score: 48.5 bits;  conditional E-value: 1.2e-16
                EEEEEEE---EEE---SS-S-----BS--EEEEEEEETTT-SB--GGG---TTEEEEEEEEETTSSSB- CS
      Velvet  1 ysLevvQqPkrARmCgfgdkdrrpidPppvvqLrvtdaetnsevdveeldssffvvtvdLwsedgtkev 69
                ++L v+QqP++AR++g ++k+r p+dPppv+qL v    + s      l+s+++++ ++L+++  ++ v
  EEA20265.1  9 FELIVRQQPEQARVAGGKEKERKPVDPPPVIQLKVLP--ESSYLAQHYLQSPYYFMCCNLYHATEDHPV 75
                689*********************************9..344445567**************5544443 PP

  == domain 2  score: 114.4 bits;  conditional E-value: 8.9e-37
                 ----EESEEE--EEE-EEEE-TT--EEEEEE---EEESS-EEEEEEEEEEE-B-S--B--S..SEEEEEEEEE---EEEE-TTT--------HHHHHHH CS
      Velvet 140 sskltrnLiGslvasafrlkdpedkpgifFvfqDLSVRteGtFrLrfrlvnvgaeavaveekegsapvlaevfSdpFtVysakkFpGvlesTaLskala 238
                 ss++   L G+lv+s+ rlkd+++++g fFvf DLS++ eG+FrL+f+l+++++         +++  l++++S++F V ++k+FpG++esT+Ls+++a
  EEA20265.1  77 SSQPSTALAGTLVSSLHRLKDTDNTDGGFFVFGDLSIKVEGEFRLQFTLFEMQK---------DNVVALKSIVSNSFPVLTPKNFPGMRESTPLSRSFA 166
                 6778899***********************************************.........999********************************* PP

                 HTT----XXXX CS
      Velvet 239 kqGikipiRkd 249
                 +qG+k++iRk+
  EEA20265.1 167 DQGVKLRIRKE 177
                 *********94 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 0.25
                 - CS
      Velvet 107 s 107
                 +
  EEA20265.1 240 Q 240
                 1 PP

>> SPR1  Psoriasis susceptibility locus 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   1.7   6.7e-06      0.06      17      86 ..     199     270 ..     181     275 .. 0.83
   2 ?    2.0   0.2     0.032   2.9e+02      52      81 ..     282     311 ..     260     320 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 6.7e-06
        SPR1  17 gsptlplgppipgdpwpgapp..lfeeppppgpsrpwrdlpesgvwppeppstdppqpplpddpwpagsqpp 86 
                  sp  p+ p i    +pg p    +   p+p+  r+  d+++  v+ p++  + + qp       p   q p
  EEA20265.1 199 RSPDRPQMPQIVSSAFPGYPQhsYYATTPAPKRVRTSMDMDQRAVFEPDARFAPTYQPTTMYSNQPGAYQTP 270
                 5789999999*********963368999**********************9999999988777777666665 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.032
        SPR1  52 rdlpesgvwppeppstdppqpplpddpwpa 81 
                   +pe gv p +p +++ +  p  +dp  a
  EEA20265.1 282 VTMPEYGVRPQQPLTSTGSSYPTSEDPMLA 311
                 568999****99999999999*****9866 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (328 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       385  (0.0214736); expected 358.6 (0.02)
Passed bias filter:                      315  (0.0175693); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 2165.52
//
Query:       EEA20266.1  [L=330]
Description: developmental regulator VosA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-45  156.5   8.3    8.1e-33  114.4   0.3    2.6  3  Velvet    Velvet factor
  ------ inclusion threshold ------
      0.027   15.0   5.2      0.061   13.8   1.7    2.4  2  SPR1      Psoriasis susceptibility locus 2


Domain annotation for each model (and alignments):
>> Velvet  Velvet factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.4   0.1   1.2e-16   1.1e-12       1      69 [.      11      77 ..      11      85 .. 0.82
   2 !  114.4   0.3     9e-37   8.1e-33     140     249 ..      79     179 ..      73     181 .. 0.95
   3 ?   -1.7   0.4      0.25   2.2e+03     107     107 ..     242     242 ..     184     312 .. 0.49

  Alignments for each domain:
  == domain 1  score: 48.4 bits;  conditional E-value: 1.2e-16
                EEEEEEE---EEE---SS-S-----BS--EEEEEEEETTT-SB--GGG---TTEEEEEEEEETTSSSB- CS
      Velvet  1 ysLevvQqPkrARmCgfgdkdrrpidPppvvqLrvtdaetnsevdveeldssffvvtvdLwsedgtkev 69
                ++L v+QqP++AR++g ++k+r p+dPppv+qL v    + s      l+s+++++ ++L+++  ++ v
  EEA20266.1 11 FELIVRQQPEQARVAGGKEKERKPVDPPPVIQLKVLP--ESSYLAQHYLQSPYYFMCCNLYHATEDHPV 77
                689*********************************9..344445567**************5544443 PP

  == domain 2  score: 114.4 bits;  conditional E-value: 9e-37
                 ----EESEEE--EEE-EEEE-TT--EEEEEE---EEESS-EEEEEEEEEEE-B-S--B--S..SEEEEEEEEE---EEEE-TTT--------HHHHHHH CS
      Velvet 140 sskltrnLiGslvasafrlkdpedkpgifFvfqDLSVRteGtFrLrfrlvnvgaeavaveekegsapvlaevfSdpFtVysakkFpGvlesTaLskala 238
                 ss++   L G+lv+s+ rlkd+++++g fFvf DLS++ eG+FrL+f+l+++++         +++  l++++S++F V ++k+FpG++esT+Ls+++a
  EEA20266.1  79 SSQPSTALAGTLVSSLHRLKDTDNTDGGFFVFGDLSIKVEGEFRLQFTLFEMQK---------DNVVALKSIVSNSFPVLTPKNFPGMRESTPLSRSFA 168
                 6778899***********************************************.........999********************************* PP

                 HTT----XXXX CS
      Velvet 239 kqGikipiRkd 249
                 +qG+k++iRk+
  EEA20266.1 169 DQGVKLRIRKE 179
                 *********94 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 0.25
                 - CS
      Velvet 107 s 107
                 +
  EEA20266.1 242 Q 242
                 1 PP

>> SPR1  Psoriasis susceptibility locus 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   1.7   6.8e-06     0.061      17      86 ..     201     272 ..     183     277 .. 0.83
   2 ?    2.0   0.2     0.032   2.9e+02      52      81 ..     284     313 ..     262     322 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 6.8e-06
        SPR1  17 gsptlplgppipgdpwpgapp..lfeeppppgpsrpwrdlpesgvwppeppstdppqpplpddpwpagsqpp 86 
                  sp  p+ p i    +pg p    +   p+p+  r+  d+++  v+ p++  + + qp       p   q p
  EEA20266.1 201 RSPDRPQMPQIVSSAFPGYPQhsYYATTPAPKRVRTSMDMDQRAVFEPDARFAPTYQPTTMYSNQPGAYQTP 272
                 5789999999*********963368999**********************9999999988777777666665 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.032
        SPR1  52 rdlpesgvwppeppstdppqpplpddpwpa 81 
                   +pe gv p +p +++ +  p  +dp  a
  EEA20266.1 284 VTMPEYGVRPQQPLTSTGSSYPTSEDPMLA 313
                 568999****99999999999*****9866 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (330 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       391  (0.0218082); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 2362.31
//
Query:       EEA20267.1  [L=1069]
Description: histone acetyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.3e-75  250.8   0.0    9.6e-75  250.2   0.0    1.2  1  MOZ_SAS         MOZ/SAS family
    4.8e-21   74.1   3.3    1.1e-20   73.0   3.3    1.6  1  zf-MYST         MYST family zinc finger domain
    6.6e-12   45.4   8.6    2.8e-11   43.3   8.0    2.4  2  PHD_4           PHD-finger
  ------ inclusion threshold ------
      0.035   14.0  14.1      0.013   15.3  10.0    2.2  2  PHD             PHD-finger


Domain annotation for each model (and alignments):
>> MOZ_SAS  MOZ/SAS family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  250.2   0.0   2.1e-78   9.6e-75       1     173 [.     536     707 ..     536     711 .. 0.97

  Alignments for each domain:
  == domain 1  score: 250.2 bits;  conditional E-value: 2.1e-78
     MOZ_SAS   1 ppGkeiYrkeklsvfevdGekeklycqnLcllaklFldhktlyydvepFlfYvlteadeegahivGyFskekesaeeynlaCilvlPpyqrkgyGklli 99 
                 ppG+eiYr+ ++s++evdG+k+ +ycqnLcllaklFl +ktlyydvepFlfYv+te+de g+h+vGyFskek  ++++n++Cil+lP +qrkgyG+lli
  EEA20267.1 536 PPGDEIYRDGSVSIYEVDGRKNPVYCQNLCLLAKLFLGSKTLYYDVEPFLFYVMTEYDELGCHFVGYFSKEKRPSSSNNVSCILTLPIHQRKGYGNLLI 634
                 8************************************************************************************************** PP

     MOZ_SAS 100 efsYeLskrekkigtPekPlsdlgllsyrsywkeeilellkekekkkisieeisektgikeeDiistleelkll 173
                 +fsY L+++ekk+g+PekPlsd+gl+syr+yw+ ++   l++ +k+ +si+e+s++tg++++Di+s le l+ l
  EEA20267.1 635 DFSYLLTRVEKKTGSPEKPLSDMGLVSYRNYWRLVLSYQLRD-QKTPVSIAELSDRTGMTADDIVSGLEGLRAL 707
                 *********************************999999887.6699*********************988765 PP

>> zf-MYST  MYST family zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.0   3.3   2.4e-24   1.1e-20       3      55 .]     479     531 ..     478     531 .. 0.98

  Alignments for each domain:
  == domain 1  score: 73.0 bits;  conditional E-value: 2.4e-24
     zf-MYST   3 niekieiGeyeiktWYfSpYPeelankekLyvCefClkYmksakelerHkkkC 55 
                 +i+ i++G yei+tWY +pYPee+++++ Ly+CefClkYm+s+  + rHk kC
  EEA20267.1 479 KIKWINFGGYEIETWYAAPYPEEYSRNKVLYICEFCLKYMNSDFVAWRHKLKC 531
                 5889************************************************* PP

>> PHD_4  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.3   8.0   6.3e-15   2.8e-11       4      68 .]     168     225 ..     167     225 .. 0.92
   2 ?   -1.7   0.0       0.7   3.1e+03      21      44 ..     447     470 ..     434     478 .. 0.75

  Alignments for each domain:
  == domain 1  score: 43.3 bits;  conditional E-value: 6.3e-15
       PHD_4   4 taaCivCgedgkedevveeesetpsslmeCsvCyeivHpeClkekegegvvnedlpnsWeCpkCv 68 
                 +++Ci+Cg+d+++d     +se  +++++C+vC +++H++C++e  ++    ++ ++ W+C  Cv
  EEA20267.1 168 RSNCIFCGQDEDHD-----PSEDFEEYLTCAVCGDHSHRQCARE--QNAFSDDEDAERWRCTVCV 225
                 579***********.....7999*******************99..4589999***********6 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.7
       PHD_4  21 eeesetpsslmeCsvCyeivHpeC 44 
                 ++e++ + ++me +   e+ H++ 
  EEA20267.1 447 SAEEDWQRKVMESESVGEVNHRAS 470
                 5668899999**999999999975 PP

>> PHD  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.3  10.0     3e-06     0.013       2      51 ..     171     226 ..     170     227 .. 0.82
   2 ?   -0.4   0.1      0.24   1.1e+03      38      50 ..     503     515 ..     496     517 .. 0.68

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 3e-06
                 BTTTTS.....TTSTTSCEEEETTTSCEEETTTSSSTHSHHSHHSS.TBSSTTTHT CS
         PHD   2 CavCkk.....ksdeeeelvqCdgCkrwfHqkClkppleseekpeg.ewlCekCke 51 
                 C +C++      s++ ee + C  C+++ H +C + +   +++++  +w C+ C +
  EEA20267.1 171 CIFCGQdedhdPSEDFEEYLTCAVCGDHSHRQCAREQNAFSDDEDAeRWRCTVCVQ 226
                 99***98655444557899***************9998877776667*******75 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.24
                 SHHSSTBSSTTTH CS
         PHD  38 ekpegewlCekCk 50 
                 ++ +  ++Ce C 
  EEA20267.1 503 SRNKVLYICEFCL 515
                 44445899*9995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1069 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1166  (0.0650343); expected 358.6 (0.02)
Passed bias filter:                      539  (0.030063); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.15u 0.37s 00:00:01.52 Elapsed: 00:00:00.61
# Mc/sec: 5288.67
//
Query:       EEA20268.1  [L=86]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.6e-26   90.2   0.1    8.2e-26   89.9   0.1    1.1  1  MWFE      NADH-ubiquinone oxidoreductase MWFE subunit


Domain annotation for each model (and alignments):
>> MWFE  NADH-ubiquinone oxidoreductase MWFE subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.9   0.1   4.6e-30   8.2e-26       1      55 []       4      58 ..       4      58 .. 1.00

  Alignments for each domain:
  == domain 1  score: 89.9 bits;  conditional E-value: 4.6e-30
        MWFE  1 PfEaLlpygImiamfgitgaglskirklqnggkraRhsvdqWdrqvmdRDrrLtG 55
                PfEaLlpygI+i+m+++tg+gls++++++n++k+aR+++d Wd+q+m+RD r+tG
  EEA20268.1  4 PFEALLPYGIIIGMYCVTGVGLSITKYYANDHKKARWNRDVWDKQMMERDFRITG 58
                9*****************************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (86 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       348  (0.0194099); expected 358.6 (0.02)
Passed bias filter:                      275  (0.0153383); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.34s 00:00:00.88 Elapsed: 00:00:00.54
# Mc/sec: 477.89
//
Query:       EEA20269.1  [L=289]
Description: DlpA domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.4e-26   91.1   0.2      1e-25   90.7   0.2    1.2  1  RraA-like     Aldolase/RraA
  ------ inclusion threshold ------
      0.046   14.1   0.0      0.097   13.0   0.0    1.5  1  NTP_transf_3  MobA-like NTP transferase domain


Domain annotation for each model (and alignments):
>> RraA-like  Aldolase/RraA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.7   0.2   1.1e-29     1e-25       2     150 .]      66     245 ..      65     245 .. 0.81

  Alignments for each domain:
  == domain 1  score: 90.7 bits;  conditional E-value: 1.1e-29
                 HHHHHH.......................CEE-SSBSTB.TT.EES.....EEEEEEEEEESS............BG..HHHHHHHTS--TTEEEEEES CS
   RraA-like   2 advsDa.......................lkklggrsggirplers.....fvGpavTvkvvea...........dn..slvkealeeagpgdvlVvdg 59 
                 +dvsDa                       +  + gr         +     ++ pavT k++++           +n     k+ ++  +pg++ V+d+
  EEA20269.1  66 CDVSDAlvklqkgpagspvragqladispMSPFIGR---------QankskIIAPAVTFKFIPKgdaaptvsdpeKNgfPPGKHWVDWNQPGTIAVLDQ 155
                 999999655555444444443333333332222222.........14556789********999999999987763355778999*************8 PP

                 TT.SSSSSECE-HHHHHHHHHTTBSEEEEEEEES-HHHHTTSSSEEEEEEE-SSB-B-S.STSEESS-EEETTEEE-TTSEEEEET.TEEEE CS
   RraA-like  60 ggdeslraallGgllataakangvaGvvvdGavRDvaelreldfpvfargvtprkkpkkkgkgevnvpveiggvtvkpgdlivaDe.dGvvv 150
                     ++ +a+lGg++a+++ + gv++vvv+G+vRD+ael+  ++ v++++++ ++++ ++++g  nvp+ ++gvtv +gd++++D  +Gvvv
  EEA20269.1 156 PA--EQYCAVLGGIMAARMSYIGVKAVVVNGRVRDLAELSVSGLHVWSKATSTVGTGAEAKAGLRNVPIDFNGVTVDTGDIVFCDPlEGVVV 245
                 88..5589999********************************************99999999**********************6488886 PP

>> NTP_transf_3  MobA-like NTP transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   1.1e-05     0.097      31     101 ..     169     239 ..     164     241 .. 0.91

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 1.1e-05
                   HHHHCTT.-CEEEEECSHCHHHHHHTTCTS-EEE-TTSS-SHHHHHHHHHHHH..SSSCEEEEETT-TT--H CS
  NTP_transf_3  31 ldalraagvdevvvvggdeevlaalarlgvrvvededpgkgplaslaaalraaa.dadavlvlacDmPlltp 101
                   +++++  gv+ vvv+g+ ++++ +l  +g++v++ + +  g++a  +a+lr+++ d  +v v ++D+++ +p
    EEA20269.1 169 AARMSYIGVKAVVVNGRVRDLA-ELSVSGLHVWSKATSTVGTGAEAKAGLRNVPiDFNGVTVDTGDIVFCDP 239
                   677888899*********9986.7999*************************888*************9886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (289 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       476  (0.0265492); expected 358.6 (0.02)
Passed bias filter:                      449  (0.0250432); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.32s 00:00:00.93 Elapsed: 00:00:00.53
# Mc/sec: 1632.47
//
Query:       EEA20270.1  [L=313]
Description: DlpA domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.3e-22   80.6   0.1      3e-21   76.1   0.1    2.1  1  RraA-like  Aldolase/RraA


Domain annotation for each model (and alignments):
>> RraA-like  Aldolase/RraA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.1   0.1   1.7e-25     3e-21       2     150 .]      66     269 ..      65     269 .. 0.76

  Alignments for each domain:
  == domain 1  score: 76.1 bits;  conditional E-value: 1.7e-25
                 HHHHHH.......................CEE-SSBSTB.TT.EES.....EEEEEEEEEESS............BG..HHHHHHHTS--TTEEEEEES CS
   RraA-like   2 advsDa.......................lkklggrsggirplers.....fvGpavTvkvvea...........dn..slvkealeeagpgdvlVvdg 59 
                 +dvsDa                       +  + gr         +     ++ pavT k++++           +n     k+ ++  +pg++ V+d+
  EEA20270.1  66 CDVSDAlvklqkgpagspvragqladispMSPFIGR---------QankskIIAPAVTFKFIPKgdaaptvsdpeKNgfPPGKHWVDWNQPGTIAVLDQ 155
                 899999655554444444443333333332222222.........14556788********999999999987763355778999*************8 PP

                 TT.SSSSSECE-HHHHHHHHHTTBSEEEEEEEES-HHHHTTSSSEEEEEEE........................-SSB-B-S.STS........EESS CS
   RraA-like  60 ggdeslraallGgllataakangvaGvvvdGavRDvaelreldfpvfargv........................tprkkpkkkgkg........evnv 126
                     ++ +a+lGg++a+++ + gv++vvv+G+vRD+ael+  ++ v a+++                        + +        g          nv
  EEA20270.1 156 PA--EQYCAVLGGIMAARMSYIGVKAVVVNGRVRDLAELSVSGLHVSALQRicfqlppssltkhfqrtqvwskatSTV--------GtgaeakagLRNV 244
                 88..5589999****************************************999999999988888866554443222........1334343337*** PP

                 -EEETTEEE-TTSEEEEET.TEEEE CS
   RraA-like 127 pveiggvtvkpgdlivaDe.dGvvv 150
                 p+ ++gvtv +gd++++D  +Gvvv
  EEA20270.1 245 PIDFNGVTVDTGDIVFCDPlEGVVV 269
                 ******************6488886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (313 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       543  (0.0302861); expected 358.6 (0.02)
Passed bias filter:                      503  (0.0280551); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 2224.25
//
Query:       EEA20271.1  [L=219]
Description: DlpA domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    8.6e-22   77.9   0.3    2.6e-20   73.1   0.3    2.1  1  RraA-like  Aldolase/RraA


Domain annotation for each model (and alignments):
>> RraA-like  Aldolase/RraA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.1   0.3   1.4e-24   2.6e-20      22     150 .]      10     175 ..       2     175 .. 0.82

  Alignments for each domain:
  == domain 1  score: 73.1 bits;  conditional E-value: 1.4e-24
                 EES.EEEEEEEEEESS............BG..HHHHHHHTS--TTEEEEEESTT.SSSSSECE-HHHHHHHHHTTBSEEEEEEEES-HHHHTTSSSEEE CS
   RraA-like  22 ers.fvGpavTvkvvea...........dn..slvkealeeagpgdvlVvdgggdeslraallGgllataakangvaGvvvdGavRDvaelreldfpvf 106
                 ++s ++ pavT k++++           +n     k+ ++  +pg++ V+d+    ++ +a+lGg++a+++ + gv++vvv+G+vRD+ael+  ++ v 
  EEA20271.1  10 NKSkIIAPAVTFKFIPKgdaaptvsdpeKNgfPPGKHWVDWNQPGTIAVLDQPA--EQYCAVLGGIMAARMSYIGVKAVVVNGRVRDLAELSVSGLHVS 106
                 33348899******999999998887763355678999*************888..5589999************************************ PP

                 EEEE........................-SSB-B-S.STS........EESS-EEETTEEE-TTSEEEEET.TEEEE CS
   RraA-like 107 argv........................tprkkpkkkgkg........evnvpveiggvtvkpgdlivaDe.dGvvv 150
                 a+++                        + +        g          nvp+ ++gvtv +gd++++D  +Gvvv
  EEA20271.1 107 ALQRicfqlppssltkhfqrtqvwskatSTV--------GtgaeakagLRNVPIDFNGVTVDTGDIVFCDPlEGVVV 175
                 ****999999999988888866554443222........1334343337*********************6488886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (219 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       314  (0.0175135); expected 358.6 (0.02)
Passed bias filter:                      290  (0.0161749); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.29s 00:00:00.72 Elapsed: 00:00:00.44
# Mc/sec: 1488.82
//
Query:       EEA20272.1  [L=857]
Description: vacuolar ATPase 98 kDa subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
          0 1068.6   0.0          0 1068.4   0.0    1.0  1  V_ATPase_I   V-type ATPase 116kDa subunit family
  ------ inclusion threshold ------
       0.02   14.5   2.3        3.4    7.2   0.1    2.2  2  Filament     Intermediate filament protein
      0.049   14.2   2.3       0.17   12.4   2.3    1.9  1  DUF1218      Protein of unknown function (DUF1218)
      0.057   13.3   0.7        1.1    9.1   0.0    2.3  2  CheZ         Chemotaxis phosphatase, CheZ
      0.088   11.6   0.1       0.13   11.0   0.1    1.2  1  PIF2         Per os infectivity factor 2
        0.1   12.5   0.6         36    4.2   0.0    3.9  4  DASH_Dam1    DASH complex subunit Dam1
       0.54   10.1   2.0         20    5.0   0.1    3.1  3  CdvA         CdvA-like coiled-coil domain
        2.8    7.9   4.1         13    5.8   0.3    2.9  3  Prefoldin_2  Prefoldin subunit


Domain annotation for each model (and alignments):
>> V_ATPase_I  V-type ATPase 116kDa subunit family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ! 1068.4   0.0         0         0       2     813 .]      31     847 ..      30     847 .. 0.94

  Alignments for each domain:
  == domain 1  score: 1068.4 bits;  conditional E-value: 0
  V_ATPase_I   2 eLGelglvqfrDlnedvnafqrkfvkevrrcdemerklrfleeeieklekavikeeeaeesleapeekeldeleeelekleeelkelnenleklkkeln 100
                 +LGe+g+vqfrDln+dvn+fqr+f+ke+rr++++er+lr++++++ek++ +++ ++e  ++l+ap+++e+del e+ e le+++ +ln+++e+lkk+  
  EEA20272.1  31 ALGEVGQVQFRDLNPDVNSFQRTFTKEIRRLENVERQLRYFSSQMEKANITMRPSSEFGNTLAAPSSAEIDELAERSEGLEQRIVSLNDSYETLKKREM 129
                 79*********************************************99999999999***************************************** PP

  V_ATPase_I 101 elvelkavlekakefleeeeeeeeeeeseeeeee.......keeeeeeeseeeeeeelleeeeelsfvaGvikrekveaferilwralrgnlflrqaei 192
                 el+e+++vl++a  f+++++ ++ee ++ + + +       ++ e++ + + +++ +++ + ++++fvaGvi+re++ +ferilwr+lrgnl+++q+ei
  EEA20272.1 130 ELIEWRWVLREAGGFFDRAHGHTEEIRT-SVDGDgddapllQDVEHQVPRNGDAQGQQSFSVMNIGFVAGVIPRERIGSFERILWRTLRGNLYMNQSEI 227
                 ****************988433333222.222222234444344444444444444444444559********************************** PP

  V_ATPase_I 193 eepledpetgekveksvfiiffqgeqlkekikkicesfgaklyelpeseeereeklkeveeriedlekvleqteealkevleeiakeleewklkvkkek 291
                 +ep++dp+t+e+++k+vf+if++g+++ +ki+ki es+ga+ly ++e++e r+++++ev++r+ d+e+vl++t+++l+++l++ia++l++w+++vkkek
  EEA20272.1 228 PEPIIDPATNEEIHKNVFVIFAHGKEILSKIRKISESLGASLYGVDENSELRRDQIHEVNTRLGDVESVLRNTTNTLEAELTQIARSLAAWMIIVKKEK 326
                 *************************************************************************************************** PP

  V_ATPase_I 292 aiyhtLnlfnldvtkkvliaegWvpkeeleeiqkalkeateessssvpsilneietketpPTyfrtnkfteafQeivdaYGiarYrEvNpalftiitFP 390
                 ++yhtLn+f++d+++k+liae+Wvp+++l +i+++l++++++++ svp+i+n+i+t++tpPTy++tnkfteafQ+i++aYGi +Y EvNp+l tiitFP
  EEA20272.1 327 SVYHTLNKFSYDQARKTLIAEAWVPTNSLPSIKSTLQDVNDRAGLSVPTIVNQIRTNKTPPTYVKTNKFTEAFQTIINAYGITKYSEVNPGLPTIITFP 425
                 *************************************************************************************************** PP

  V_ATPase_I 391 FlFavMFGDiGHGlllllfalllvlkekklkkkkkdeilemlfsgRYiillmGlfsiYtGliYNdifskslnlfgSswevkekaveeeelkkekkeekv 489
                 FlFavMFGD+GHG+l++l+a++++++ek+l ++k de++ m+f gRYi+l+mG+fs+YtGliYNd+fs+s+++f S+w++++++ e + ++++ k++  
  EEA20272.1 426 FLFAVMFGDFGHGFLMTLTATAMIVFEKTLLRTKLDELTYMAFYGRYIMLMMGIFSMYTGLIYNDVFSLSFEFFPSQWQWPHNIDEGQVVHATLKQGYR 524
                 ********************************************************************************99998888889999***** PP

  V_ATPase_I 490 YpfGlDpaWklaenellflnSlKmKlsvilGviqMlfgvllslvNalyfkkkldiilefiPqllfllsifgYlvlliiyKWlvdweaekekapsllntl 588
                 YpfGlD+ W+ aen+llf+nS+KmKls+++G+++M++++ l+++Na++fk+k+di+ +f+P+++f++sifgYl ++i+yKW++dw+a+ e++p+lln+l
  EEA20272.1 525 YPFGLDWNWHEAENALLFTNSYKMKLSILMGWAHMTYSLSLQYINARHFKSKVDILGNFLPGMIFFQSIFGYLAFTIVYKWSIDWNARGESPPGLLNML 623
                 **************************************************************************************88888******** PP

  V_ATPase_I 589 inmflskgkvkeeelyegqetvqvvLlllalvcvpvlllvkPlilklkhkkkkkkkekkkeeeee.eeeeeeeeeeeeeeeaeeeeeeeeeeeeeeeee 686
                 i mfls+g++ e++ly+gq+ vq++Ll la ++vp++ll+kPl+l+++h++++  +++   e+++ ++ +e+ + + +  +a +++ +++ e+  + ++
  EEA20272.1 624 IFMFLSPGTI-EQQLYPGQAGVQKFLLGLAALQVPIMLLLKPLWLRREHNRARGLGYQGIGERAHvSALDEDGDLNGHA-SAARDSIASDGEAVAMIAQ 720
                 **********.99**********************************************99999744444444444444.4555556667777778888 PP

  V_ATPase_I 687 eeeeeeeeefdfgevfihqvIhtIEfvLgciSnTASYLRLWALSLAHaqLseVlwemvlkkallksksvlgvillvilfavfavltvavLllmeglsaf 785
                 + +e e+eefdf++ +ihq+IhtIEf+L+ciS+TASYLRLWALSLAH+qLs Vlw+m+l  a+  ++s++++il+v+ f+++++ltva+L++meg+sa+
  EEA20272.1 721 DIDEGEHEEFDFSDEMIHQIIHTIEFCLNCISHTASYLRLWALSLAHQQLSIVLWTMTLGGAFGIEGSTTRIILIVFSFYLWFTLTVAILCVMEGTSAM 819
                 89999********************************************************9988899******************************* PP

  V_ATPase_I 786 LHaLRLhWVEfqsKFykgdGykFepfsf 813
                 LH+LRLhWVE++sK++ gdG++F+pfsf
  EEA20272.1 820 LHSLRLHWVEAMSKHFIGDGIPFQPFSF 847
                 ***************************9 PP

>> Filament  Intermediate filament protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.3    0.0018       4.1      74     139 ..      37     127 ..      22     139 .. 0.87
   2 ?    7.2   0.1    0.0015       3.4     215     279 ..     252     316 ..     235     319 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0018
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.........................XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
    Filament  74 qleldnlreeledlrkkyekelnkreevEaelkalr.........................kdldeatlarvdLekkvesLkeelaflkkv 139
                 q++ ++l+ +++ ++  + ke+++ e+vE++l+ +                           ++de+  +   Le+++ sL++  + lkk 
  EEA20272.1  37 QVQFRDLNPDVNSFQRTFTKEIRRLENVERQLRYFSsqmekanitmrpssefgntlaapssAEIDELAERSEGLEQRIVSLNDSYETLKKR 127
                 688899999************************9998999999999999999999999998889888888888999999999999999875 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0015
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Filament 215 keeitelrrqiqsleieleslkkqkasleaqlaeleerleaeleklqeklseleeelaeireema 279
                 ke ++++r+  +sl + l  + ++++  ++q++e++ rl    + l+++ + le+el++i + +a
  EEA20272.1 252 KEILSKIRKISESLGASLYGVDENSELRRDQIHEVNTRLGDVESVLRNTTNTLEAELTQIARSLA 316
                 4456788888899*********************************************9977665 PP

>> DUF1218  Protein of unknown function (DUF1218)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   2.3   7.5e-05      0.17      22      59 ..     781     818 ..     738     829 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 7.5e-05
     DUF1218  22 rkekspssakrtlavvlfvlswivfaiAvalllvGaav 59 
                 ++   ++s++r++ +v+++  w+++++A+++++ G++ 
  EEA20272.1 781 GAFGIEGSTTRIILIVFSFYLWFTLTVAILCVMEGTSA 818
                 333477888**************************975 PP

>> CheZ  Chemotaxis phosphatase, CheZ
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.0    0.0005       1.1      16     117 ..      56     157 ..      33     160 .. 0.75
   2 ?    2.1   0.1     0.068   1.5e+02       8      90 ..     259     341 ..     250     368 .. 0.65

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0005
                 XXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        CheZ  16 dalrelgldekllekaaeeipdardrLeyvielTeqAAertldavekalpladklkeeakeleeewerllerelekeefrelvkeveaflkeveektea 114
                   +r l+  e++l+  +++++ a+  ++   e  ++ A  +   +++ +   + l++++ +l++++e+l++re+e+ e r +++e   f+++++ +te+
  EEA20272.1  56 KEIRRLENVERQLRYFSSQMEKANITMRPSSEFGNTLAAPSSAEIDELAERSEGLEQRIVSLNDSYETLKKREMELIEWRWVLREAGGFFDRAHGHTEE 154
                 4555555444555555555555555555555555555555556779999999*********************************************99 PP

                 XXX CS
        CheZ 115 lkk 117
                 +++
  EEA20272.1 155 IRT 157
                 876 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.068
                 XXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        CheZ   8 GkltReLhdalrelgldekllekaaeeipdardrL...eyvielTeqAAertldavekalpladklkeeakeleeewerllerele 90 
                  k+  +L  +l  +g+d +++e  +++i++ + rL   e v++ T +  e  l+ + ++l+    + ++ k++ ++++++   +++
  EEA20272.1 259 RKISESLGASL--YGVD-ENSELRRDQIHEVNTRLgdvESVLRNTTNTLEAELTQIARSLAAWMIIVKKEKSVYHTLNKFSYDQAR 341
                 33333333333..3466.66777777777777777333456777777777777777777777777777777777777777666655 PP

>> PIF2  Per os infectivity factor 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.1     6e-05      0.13      14      97 ..     312     392 ..     306     405 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 6e-05
        PIF2  14 akplleavldvvreqleyentveerleeieetlarrryvplealpnirlnanfdtlagetkcfsvpvlvttvesssfdcsavcd 97 
                 a+ l   +++v++e+  y++  +   ++ ++tl    +vp ++lp+i+    ++ ++ +   +svp++v ++++++   + v  
  EEA20272.1 312 ARSLAAWMIIVKKEKSVYHTLNKFSYDQARKTLIAEAWVPTNSLPSIKS--TLQDVN-DRAGLSVPTIVNQIRTNKTPPTYVKT 392
                 56667777888999999999999999********************974..555554.3678**********998876666655 PP

>> DASH_Dam1  DASH complex subunit Dam1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0      0.63   1.4e+03      13      32 ..      52      71 ..      37      74 .. 0.59
   2 ?    2.3   0.1     0.066   1.5e+02       5      30 ..     100     125 ..      97     133 .. 0.67
   3 ?    4.2   0.0     0.016        36      24      46 ..     253     275 ..     246     277 .. 0.84
   4 ?   -0.2   0.0      0.41   9.2e+02       5      40 ..     283     319 ..     280     322 .. 0.67

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.63
   DASH_Dam1 13 etLdknledLqqihesLsdf 32
                +t++k +++L++++ +L  f
  EEA20272.1 52 RTFTKEIRRLENVERQLRYF 71
                35566667788888777766 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.066
   DASH_Dam1   5 faeLaDsletLdknledLqqihesLs 30 
                 + eLa+  e L++++  L++  e+L+
  EEA20272.1 100 IDELAERSEGLEQRIVSLNDSYETLK 125
                 56677777777777777777666665 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.016
   DASH_Dam1  24 qihesLsdfNeSFasfLYGLnmn 46 
                 +i  ++ + +eS+++ LYG   n
  EEA20272.1 253 EILSKIRKISESLGASLYGVDEN 275
                 677789999**********8776 PP

  == domain 4  score: -0.2 bits;  conditional E-value: 0.41
   DASH_Dam1   5 faeLaDsletLdknled.LqqihesLsdfNeSFasfL 40 
                 ++e +  l ++++ l++  + ++ +L++  +S+a+++
  EEA20272.1 283 IHEVNTRLGDVESVLRNtTNTLEAELTQIARSLAAWM 319
                 5555555666665555413677889999999999986 PP

>> CdvA  CdvA-like coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0     0.055   1.2e+02       4      61 ..      13      70 ..      11      81 .. 0.88
   2 ?   -0.5   0.1      0.45     1e+03      49      70 ..     100     121 ..      89     131 .. 0.55
   3 ?    5.0   0.1    0.0088        20      28      66 ..     280     318 ..     271     324 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.055
        CdvA  4 kALeeLvsegdipkstyeeikekleealkklkekakelkeklkkrlkeledqikslek 61
                + L +L+  ++i +++++ + e  + ++++l+ + +  + + +k+++ le+  ++l  
  EEA20272.1 13 MSLTQLYIANEIGREVVSALGEVGQVQFRDLNPDVNSFQRTFTKEIRRLENVERQLRY 70
                6799999999999999999999999999999999999999999999999998888865 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.45
        CdvA  49 lkeledqikslekalanlkisy 70 
                 ++el +  + le+ +++l  sy
  EEA20272.1 100 IDELAERSEGLEQRIVSLNDSY 121
                 4444444444444444444443 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.0088
        CdvA  28 eealkklkekakelkeklkkrlkeledqikslekalanl 66 
                 ++++ +++ +  ++ + l++ +++le ++++++++la+ 
  EEA20272.1 280 RDQIHEVNTRLGDVESVLRNTTNTLEAELTQIARSLAAW 318
                 578999999**************************9986 PP

>> Prefoldin_2  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.1      0.21   4.7e+02      64      96 ..      44      76 ..      38      83 .. 0.62
   2 ?    5.8   0.3    0.0059        13      64      92 ..     100     128 ..      88     134 .. 0.84
   3 ?    0.1   0.0      0.33   7.4e+02      63      89 ..     286     312 ..     264     325 .. 0.62

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.21
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Prefoldin_2 64 keeLeerketlekeiktlekqleklekeleelk 96
                 +++++  + t +kei++le+ +++l+   ++++
   EEA20272.1 44 NPDVNSFQRTFTKEIRRLENVERQLRYFSSQME 76
                 555666666777777777776666654444444 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0059
                  HHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Prefoldin_2  64 keeLeerketlekeiktlekqleklekel 92 
                  ++eL er e le++i +l++++e+l+k+ 
   EEA20272.1 100 IDELAERSEGLEQRIVSLNDSYETLKKRE 128
                  68999******************999975 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.33
                  HHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Prefoldin_2  63 vkeeLeerketlekeiktlekqlekle 89 
                  v+++L + +  l    +tle +l+++ 
   EEA20272.1 286 VNTRLGDVESVLRNTTNTLEAELTQIA 312
                  444444444444444444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (857 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1000  (0.0557756); expected 358.6 (0.02)
Passed bias filter:                      709  (0.0395449); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.83u 0.29s 00:00:01.11 Elapsed: 00:00:00.52
# Mc/sec: 4970.16
//
Query:       EEA20273.1  [L=355]
Description: fructose-1,6-bisphosphatase Fbp1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.4e-68  227.7   0.0      1e-67  227.3   0.0    1.2  1  FBPase    Fructose-1-6-bisphosphatase, N-terminal domain


Domain annotation for each model (and alignments):
>> FBPase  Fructose-1-6-bisphosphatase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  227.3   0.0   5.8e-72     1e-67       1     189 []      21     215 ..      21     215 .. 0.96

  Alignments for each domain:
  == domain 1  score: 227.3 bits;  conditional E-value: 5.8e-72
      FBPase   1 itltrfiveeqkeeanatgeltallsalklalkiisskvrkaelvnllGlagaeNvtGdeqkklDvladeiliealkaseevkvlvSEEeeelivlere 99 
                 itltrf+ eeq + ++atg++t l  al++a+k i+  +r+a+l+nl+Glag++N+tGd+qkklDv++++++i+a++ s++v  lvSEEeee+i+++++
  EEA20273.1  21 ITLTRFLTEEQLRVPEATGDFTLLCHALQFAFKSIAYYIRRASLINLTGLAGSSNITGDDQKKLDVIGNDVFIAAMRGSGKVRLLVSEEEEEAIIFDEH 119
                 69************************************************************************************************* PP

      FBPase 100 kegkyvvafDPlDGSSnidtnvsvGtifsiyrkks.....edeettidvlqpGkeqvAAgyvvYGsstmlVltlgaG.vngFtlDpslgefiltke 189
                  +++y+v++DP+DGSSn+d++vsvGtif+i+r +      +++ + +d+l+ G e+vA g+++YG+s++lV+t+  G vngFt+++slgefilt++
  EEA20273.1 120 PNARYAVVCDPIDGSSNLDAGVSVGTIFGIFRLPDeilgpNKTVSAKDILRDGTELVASGFTMYGASAQLVITMRGGsVNGFTMENSLGEFILTHP 215
                 ********************************887889855555566***************************98659***************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (355 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       295  (0.0164538); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 2359.69
//
Query:       EEA20274.1  [L=1264]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        0.2   11.4   5.0       0.39   10.5   2.6    2.5  2  Lectin_N  Hepatic lectin, N-terminal domain
        1.2    9.6   9.3        3.5    8.1   9.3    1.8  1  AAA_23    AAA domain


Domain annotation for each model (and alignments):
>> Lectin_N  Hepatic lectin, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   2.6   4.3e-05      0.39      48     105 ..     890     948 ..     889     954 .. 0.93
   2 ?   -0.6   0.0      0.12     1e+03      87     128 ..    1145    1186 ..    1107    1188 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 4.3e-05
    Lectin_N  48 sqnsqLqreLet.Lketfsnfssstlaeiqalssqggslsekvtsleaklekkqqdlka 105
                 +q +qL++e et ++e+ + f+++++ +iq+ s +  ++ e  + lea+++kkq+d+ +
  EEA20274.1 890 QQMAQLKQEHETkIRENRKFFTANIQQQIQEGSIKYAEAAEAEAALEAEVQKKQRDIAQ 948
                 5889*****99879*****************************************9865 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.12
    Lectin_N   87 ekvtsleaklekkqqdlkadhselllhvkqlvkdLrtLsCql 128 
                  + + sl ++ ek   ++ + +++ll  + ++++ + + +C l
  EEA20274.1 1145 QYLYSLLSHAEKSTYQFIESQTNLLCLLHEVRSGVMMTNCRL 1186
                  667899999999999999999999999999999999999987 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   9.3   0.00039       3.5      67     195 ..     860    1013 ..     846    1097 .. 0.77

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00039
      AAA_23   67 segkvkayveltfenkdgrytrsiererelskkkgkttkkaklelleideleqfisellgskkiilnlilflgqerfeefelkdkke.......... 153 
                  +++ +  +++ t++++++      e + ++ + k +  + +++ +++i+e+++f++ +++++ i+   i +  + ++e  ++++ ++          
  EEA20274.1  860 NSHPDLVVYRTTVRSISDL----SEIRATREQYKQQMAQLKQEHETKIRENRKFFTANIQQQ-IQEGSIKYAEAAEAEAALEAEVQKkqrdiaqsey 951 
                  5555555677777777773....45566666667777888888999999999****998866.4455555555555433333222222556888888 PP

      AAA_23  154 .................rleelekeleeled.ekkllekl..eqekekekeleeleeeleei 195 
                                   r+ ++++ ++el+   k+ ++++   + +e+ +e  e+ e+l+++
  EEA20274.1  952 dtyqkkvmeplhlilsdRVSKATERINELSGkLKEDIQHEnpDRTQEEGDEKPEILEQLTQL 1013
                  89999999999999999888888888888863555677775535555555777777777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1264 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1581  (0.0881812); expected 358.6 (0.02)
Passed bias filter:                      541  (0.0301746); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.95u 0.32s 00:00:01.27 Elapsed: 00:00:00.49
# Mc/sec: 7755.45
//
Query:       EEA20275.1  [L=385]
Description: Aha1 domain family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.7e-41  140.5   1.5      8e-41  139.5   1.5    1.6  1  Aha1_N    Activator of Hsp90 ATPase, N-terminal
    4.4e-19   68.9   1.0    7.9e-19   68.1   1.0    1.4  1  AHSA1     Activator of Hsp90 ATPase homolog 1-like protein
  ------ inclusion threshold ------
        3.1    7.8  13.8        4.6    7.2   7.4    2.4  2  Mucin     Mucin-like glycoprotein


Domain annotation for each model (and alignments):
>> Aha1_N  Activator of Hsp90 ATPase, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.5   1.5   1.3e-44     8e-41       1     137 []      13     144 ..      13     144 .. 0.97

  Alignments for each domain:
  == domain 1  score: 139.5 bits;  conditional E-value: 1.3e-44
      Aha1_N   1 eKdatpWskerlkelllslkleneeaksvkitevksveGdasvnqrKgKvifiydlklklewegtvkkedgkkvkGeieipelssenddddyeievsvk 99 
                 +Kd++pW+k++l++ l +++ e+++ + +k+++v s++Gd++v+qrKgKvi++yd+kl+le+eg++  +d+++v+G+i+ipe+++++++d++++e+sv+
  EEA20275.1  13 NKDVSPWTKTYLQDSLSKISAEENGVS-AKVEKVLSMDGDVDVSQRKGKVITLYDVKLQLEYEGKT--KDEETVTGTITIPEVAHDTEEDEFVFEISVY 108
                 7**********************9998.*************************************8..******************************* PP

      Aha1_N 100 kdeekkekqklkelikskgvpklreklakfvkeLkeeh 137
                 ++  +++kq +k+l++sk+vp+lr +lak+ + L++eh
  EEA20275.1 109 SE--SSSKQPVKDLVRSKIVPQLRVALAKLPQVLVSEH 144
                 96..7789************************999887 PP

>> AHSA1  Activator of Hsp90 ATPase homolog 1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.1   1.0   1.3e-22   7.9e-19       2     124 ..     203     321 ..     202     322 .. 0.93

  Alignments for each domain:
  == domain 1  score: 68.1 bits;  conditional E-value: 1.3e-22
                 S-HHHHHHHHH-HHHHHHHEEEEEEEE--.STTEEEEEEETTTSEEEEEEEE..EEEEETTTEEEEEEEEETSETEEEEEEEEEEEE..ETTEEEEEEE CS
       AHSA1   2 apperVfraltdpellkrWftlteaemdl.rpGgkfrlrdspdgkefgnege..ylevvpperlvytwrledepeeeestvtielee..egggTrltlt 95 
                 +++e+++ ++tdp++++++ +++  ++d  ++Ggkf +        f+++++  y +++p +r+v++wrl+++pe+++st +i + +  ++  T + +t
  EEA20275.1 203 TTAEELYTTFTDPQRIAAFTRGPPLQFDGaKVGGKFAI--------FDGNVTgeYVTLEPFKRVVQKWRLAQWPEGHFSTQEIVFNQndVDRVTVMQVT 293
                 789*************************9788******........88888888********************************9656666****** PP

                 EEEEEHCHHHHHHHHHHHHHHH.HHHHHHH CS
       AHSA1  96 htglprkqkeeegveeGweqsl.dqLkall 124
                 +tg+p +q+e   v+ +we ++ +++k+++
  EEA20275.1 294 WTGVPIGQEEV--VQRNWEGYYvRSIKQTF 321
                 ********999..*********99999986 PP

>> Mucin  Mucin-like glycoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   7.4   0.00077       4.6      43      86 ..     168     211 ..     132     229 .. 0.58
   2 ?    3.9   0.4     0.008        48      77      99 ..     327     349 ..     311     359 .. 0.66

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.00077
       Mucin  43 skltttttttkppttttttttasttittkttkattttttttttt 86 
                 +k+ ++++ t  +ttt t + + +t+t +++    tt+ +  tt
  EEA20275.1 168 QKSSSPAVGTSKTTTTSTGKVSVNTTTVTASDEFRTTAEELYTT 211
                 33444555555555444444444443333333333333333333 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.008
       Mucin  77 tttttttttttateaPsdavtta 99 
                 ++ ++ttttt   +aPs  ++++
  EEA20275.1 327 SSFANTTTTTVPRKAPSPLTSSS 349
                 44456666666678888555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (385 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       784  (0.043728); expected 358.6 (0.02)
Passed bias filter:                      499  (0.027832); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 2692.82
//
Query:       EEA20276.1  [L=338]
Description: Aha1 domain family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.7e-41  140.2   2.4    6.1e-41  139.8   1.5    1.7  2  Aha1_N    Activator of Hsp90 ATPase, N-terminal
    3.3e-19   69.3   1.0    6.1e-19   68.5   1.0    1.5  1  AHSA1     Activator of Hsp90 ATPase homolog 1-like protein


Domain annotation for each model (and alignments):
>> Aha1_N  Activator of Hsp90 ATPase, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.8   1.5   6.8e-45   6.1e-41       1     137 []      13     144 ..      13     144 .. 0.97
   2 ?   -2.9   0.0      0.83   7.4e+03      75      91 ..     269     286 ..     237     304 .. 0.64

  Alignments for each domain:
  == domain 1  score: 139.8 bits;  conditional E-value: 6.8e-45
      Aha1_N   1 eKdatpWskerlkelllslkleneeaksvkitevksveGdasvnqrKgKvifiydlklklewegtvkkedgkkvkGeieipelssenddddyeievsvk 99 
                 +Kd++pW+k++l++ l +++ e+++ + +k+++v s++Gd++v+qrKgKvi++yd+kl+le+eg++  +d+++v+G+i+ipe+++++++d++++e+sv+
  EEA20276.1  13 NKDVSPWTKTYLQDSLSKISAEENGVS-AKVEKVLSMDGDVDVSQRKGKVITLYDVKLQLEYEGKT--KDEETVTGTITIPEVAHDTEEDEFVFEISVY 108
                 7**********************9998.*************************************8..******************************* PP

      Aha1_N 100 kdeekkekqklkelikskgvpklreklakfvkeLkeeh 137
                 ++  +++kq +k+l++sk+vp+lr +lak+ + L++eh
  EEA20276.1 109 SE--SSSKQPVKDLVRSKIVPQLRVALAKLPQVLVSEH 144
                 96..7789************************999887 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.83
      Aha1_N  75 kGeieipelsse.ndddd 91 
                 +G+++ +e+    nd d 
  EEA20276.1 269 EGHFSTQEIVFNqNDVDR 286
                 566666666666455543 PP

>> AHSA1  Activator of Hsp90 ATPase homolog 1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.5   1.0   6.8e-23   6.1e-19       2     124 ..     203     321 ..     202     322 .. 0.93

  Alignments for each domain:
  == domain 1  score: 68.5 bits;  conditional E-value: 6.8e-23
                 S-HHHHHHHHH-HHHHHHHEEEEEEEE--.STTEEEEEEETTTSEEEEEEEE..EEEEETTTEEEEEEEEETSETEEEEEEEEEEEE..ETTEEEEEEE CS
       AHSA1   2 apperVfraltdpellkrWftlteaemdl.rpGgkfrlrdspdgkefgnege..ylevvpperlvytwrledepeeeestvtielee..egggTrltlt 95 
                 +++e+++ ++tdp++++++ +++  ++d  ++Ggkf +        f+++++  y +++p +r+v++wrl+++pe+++st +i + +  ++  T + +t
  EEA20276.1 203 TTAEELYTTFTDPQRIAAFTRGPPLQFDGaKVGGKFAI--------FDGNVTgeYVTLEPFKRVVQKWRLAQWPEGHFSTQEIVFNQndVDRVTVMQVT 293
                 789*************************9788******........88888888********************************9656666****** PP

                 EEEEEHCHHHHHHHHHHHHHHH.HHHHHHH CS
       AHSA1  96 htglprkqkeeegveeGweqsl.dqLkall 124
                 +tg+p +q+e   v+ +we ++ +++k+++
  EEA20276.1 294 WTGVPIGQEEV--VQRNWEGYYvRSIKQTF 321
                 ********999..*********99999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (338 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       869  (0.048469); expected 358.6 (0.02)
Passed bias filter:                      535  (0.0298399); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 2247.93
//
Query:       EEA20277.1  [L=327]
Description: Aha1 domain family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-41  141.1   1.5    5.6e-41  139.9   1.5    1.6  1  Aha1_N    Activator of Hsp90 ATPase, N-terminal
      3e-19   69.5   1.0    5.7e-19   68.6   1.0    1.5  1  AHSA1     Activator of Hsp90 ATPase homolog 1-like protein


Domain annotation for each model (and alignments):
>> Aha1_N  Activator of Hsp90 ATPase, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.9   1.5   6.3e-45   5.6e-41       1     137 []      13     144 ..      13     144 .. 0.97

  Alignments for each domain:
  == domain 1  score: 139.9 bits;  conditional E-value: 6.3e-45
      Aha1_N   1 eKdatpWskerlkelllslkleneeaksvkitevksveGdasvnqrKgKvifiydlklklewegtvkkedgkkvkGeieipelssenddddyeievsvk 99 
                 +Kd++pW+k++l++ l +++ e+++ + +k+++v s++Gd++v+qrKgKvi++yd+kl+le+eg++  +d+++v+G+i+ipe+++++++d++++e+sv+
  EEA20277.1  13 NKDVSPWTKTYLQDSLSKISAEENGVS-AKVEKVLSMDGDVDVSQRKGKVITLYDVKLQLEYEGKT--KDEETVTGTITIPEVAHDTEEDEFVFEISVY 108
                 7**********************9998.*************************************8..******************************* PP

      Aha1_N 100 kdeekkekqklkelikskgvpklreklakfvkeLkeeh 137
                 ++  +++kq +k+l++sk+vp+lr +lak+ + L++eh
  EEA20277.1 109 SE--SSSKQPVKDLVRSKIVPQLRVALAKLPQVLVSEH 144
                 96..7789************************999887 PP

>> AHSA1  Activator of Hsp90 ATPase homolog 1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.6   1.0   6.3e-23   5.7e-19       2     124 ..     203     321 ..     202     322 .. 0.93

  Alignments for each domain:
  == domain 1  score: 68.6 bits;  conditional E-value: 6.3e-23
                 S-HHHHHHHHH-HHHHHHHEEEEEEEE--.STTEEEEEEETTTSEEEEEEEE..EEEEETTTEEEEEEEEETSETEEEEEEEEEEEE..ETTEEEEEEE CS
       AHSA1   2 apperVfraltdpellkrWftlteaemdl.rpGgkfrlrdspdgkefgnege..ylevvpperlvytwrledepeeeestvtielee..egggTrltlt 95 
                 +++e+++ ++tdp++++++ +++  ++d  ++Ggkf +        f+++++  y +++p +r+v++wrl+++pe+++st +i + +  ++  T + +t
  EEA20277.1 203 TTAEELYTTFTDPQRIAAFTRGPPLQFDGaKVGGKFAI--------FDGNVTgeYVTLEPFKRVVQKWRLAQWPEGHFSTQEIVFNQndVDRVTVMQVT 293
                 789*************************9788******........88888888********************************9656666****** PP

                 EEEEEHCHHHHHHHHHHHHHHH.HHHHHHH CS
       AHSA1  96 htglprkqkeeegveeGweqsl.dqLkall 124
                 +tg+p +q+e   v+ +we ++ +++k+++
  EEA20277.1 294 WTGVPIGQEEV--VQRNWEGYYvRSIKQTF 321
                 ********999..*********99999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (327 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       822  (0.0458475); expected 358.6 (0.02)
Passed bias filter:                      495  (0.0276089); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2356.17
//
Query:       EEA20278.1  [L=327]
Description: Aha1 domain family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-41  141.1   1.5    5.6e-41  139.9   1.5    1.6  1  Aha1_N    Activator of Hsp90 ATPase, N-terminal
      3e-19   69.5   1.0    5.7e-19   68.6   1.0    1.5  1  AHSA1     Activator of Hsp90 ATPase homolog 1-like protein


Domain annotation for each model (and alignments):
>> Aha1_N  Activator of Hsp90 ATPase, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.9   1.5   6.3e-45   5.6e-41       1     137 []      13     144 ..      13     144 .. 0.97

  Alignments for each domain:
  == domain 1  score: 139.9 bits;  conditional E-value: 6.3e-45
      Aha1_N   1 eKdatpWskerlkelllslkleneeaksvkitevksveGdasvnqrKgKvifiydlklklewegtvkkedgkkvkGeieipelssenddddyeievsvk 99 
                 +Kd++pW+k++l++ l +++ e+++ + +k+++v s++Gd++v+qrKgKvi++yd+kl+le+eg++  +d+++v+G+i+ipe+++++++d++++e+sv+
  EEA20278.1  13 NKDVSPWTKTYLQDSLSKISAEENGVS-AKVEKVLSMDGDVDVSQRKGKVITLYDVKLQLEYEGKT--KDEETVTGTITIPEVAHDTEEDEFVFEISVY 108
                 7**********************9998.*************************************8..******************************* PP

      Aha1_N 100 kdeekkekqklkelikskgvpklreklakfvkeLkeeh 137
                 ++  +++kq +k+l++sk+vp+lr +lak+ + L++eh
  EEA20278.1 109 SE--SSSKQPVKDLVRSKIVPQLRVALAKLPQVLVSEH 144
                 96..7789************************999887 PP

>> AHSA1  Activator of Hsp90 ATPase homolog 1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.6   1.0   6.3e-23   5.7e-19       2     124 ..     203     321 ..     202     322 .. 0.93

  Alignments for each domain:
  == domain 1  score: 68.6 bits;  conditional E-value: 6.3e-23
                 S-HHHHHHHHH-HHHHHHHEEEEEEEE--.STTEEEEEEETTTSEEEEEEEE..EEEEETTTEEEEEEEEETSETEEEEEEEEEEEE..ETTEEEEEEE CS
       AHSA1   2 apperVfraltdpellkrWftlteaemdl.rpGgkfrlrdspdgkefgnege..ylevvpperlvytwrledepeeeestvtielee..egggTrltlt 95 
                 +++e+++ ++tdp++++++ +++  ++d  ++Ggkf +        f+++++  y +++p +r+v++wrl+++pe+++st +i + +  ++  T + +t
  EEA20278.1 203 TTAEELYTTFTDPQRIAAFTRGPPLQFDGaKVGGKFAI--------FDGNVTgeYVTLEPFKRVVQKWRLAQWPEGHFSTQEIVFNQndVDRVTVMQVT 293
                 789*************************9788******........88888888********************************9656666****** PP

                 EEEEEHCHHHHHHHHHHHHHHH.HHHHHHH CS
       AHSA1  96 htglprkqkeeegveeGweqsl.dqLkall 124
                 +tg+p +q+e   v+ +we ++ +++k+++
  EEA20278.1 294 WTGVPIGQEEV--VQRNWEGYYvRSIKQTF 321
                 ********999..*********99999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (327 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       822  (0.0458475); expected 358.6 (0.02)
Passed bias filter:                      495  (0.0276089); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 2220.39
//
Query:       EEA20279.1  [L=450]
Description: saccharopine dehydrogenase Lys9, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.6e-92  309.7   0.0    4.1e-92  309.0   0.0    1.3  1  Sacchrp_dh_C     Saccharopine dehydrogenase C-terminal domain
      3e-25   89.0   1.2    4.6e-25   88.4   1.2    1.3  1  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma
    5.2e-07   29.8   0.4    1.1e-06   28.8   0.4    1.6  1  Shikimate_DH     Shikimate / quinate 5-dehydrogenase
    2.5e-06   27.5   0.5    4.6e-06   26.6   0.5    1.5  1  NAD_binding_10   NAD(P)H-binding
    2.8e-05   24.5   0.4    7.8e-05   23.1   0.4    1.7  1  NAD_binding_7    Putative NAD(P)-binding
    8.3e-05   22.0   1.0    0.00013   21.3   1.0    1.2  1  AlaDh_PNT_C      Alanine dehydrogenase/PNT, C-terminal domain
    0.00047   19.7   0.1     0.0013   18.3   0.1    1.6  2  Epimerase        NAD dependent epimerase/dehydratase family
     0.0025   18.5   1.4     0.0044   17.7   1.4    1.4  1  NAD_binding_3    Homoserine dehydrogenase, NAD binding domain
     0.0027   17.3   0.6     0.0043   16.6   0.6    1.3  1  NmrA             NmrA-like family
     0.0084   16.9   0.1      0.014   16.2   0.1    1.4  1  GFO_IDH_MocA     Oxidoreductase family, NAD-binding Rossmann 
     0.0085   16.5   0.2      0.016   15.6   0.2    1.5  1  Semialdhyde_dh   Semialdehyde dehydrogenase, NAD binding doma
  ------ inclusion threshold ------
       0.01   15.4   0.9      0.029   13.9   0.4    1.9  2  IlvN             Acetohydroxy acid isomeroreductase, NADPH-bi
       0.02   15.2   1.1      0.037   14.3   1.1    1.4  1  TrkA_N           TrkA-N domain
      0.056   12.8   0.1       0.13   11.6   0.1    1.6  1  2-Hacid_dh_C     D-isomer specific 2-hydroxyacid dehydrogenas
       0.11   11.4   0.1       0.19   10.7   0.1    1.3  1  3Beta_HSD        3-beta hydroxysteroid dehydrogenase/isomeras


Domain annotation for each model (and alignments):
>> Sacchrp_dh_C  Saccharopine dehydrogenase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  309.0   0.0   3.4e-95   4.1e-92       1     263 [.     128     440 ..     128     443 .. 0.92

  Alignments for each domain:
  == domain 1  score: 309.0 bits;  conditional E-value: 3.4e-95
                   BTTTBHHHHHHHHHHHCCCHTTBECCCCCCCCCCCCECCCCESTTCEEESS-HHHHHHHCCSEEEEEETTEEEECTCCCSGCC.TCEEECCCCCEEC CS
  Sacchrp_dh_C   1 GldPGidhllamkaidevkakggkiesflsycgglpapeasdnplgYkfsWspegvlreltnpakvlengqvkevpgsellkgakkpiyilpglsle 97 
                   GldPGidhl+a+k+i ev+++ggki sflsycgglpape sdnplgYkfsWs +gvl++l+n+ak++++g + +v+g++l+ +a kp++i+pg++++
    EEA20279.1 128 GLDPGIDHLYAVKTITEVHEAGGKILSFLSYCGGLPAPEDSDNPLGYKFSWSSRGVLLALRNSAKFYRDGAEFSVDGTQLMGEA-KPYFIYPGYAFV 223
                   9*******************************************************************************9755.89999******* PP

                   TTECEEECTHCHHHHHHC.SCSEEEEEEEEEHHHHHHHHHHHTTT--SCEC..C.........................................CC CS
  Sacchrp_dh_C  98 gypnrdslpyeelyglpeaktlfrgtlrypgfsellkslkelGllseepke..e.........................................al 151
                   +ypnrds+py+e y++pea+t++rgtlry+gf++++k l+++G+lse++ +  +                                         +l
    EEA20279.1 224 AYPNRDSTPYRERYNIPEAQTVVRGTLRYQGFPQMIKVLVDIGFLSETEYDflKtpitwkeatkkiigatsdkeldllwaisskttfadnderdrIL 320
                   **********************************************9983345389999**********9999999999998888888888888744 PP

                   CC..HH...ST...T.C.EHHHHHHHHCCHHCCCCTTEEEEEEEEEEEEEE.TTSEEEEEEEEEEEEE.EHHSSSHHHHHHHHHHHHHHHHHHTTSC CS
  Sacchrp_dh_C 152 ka..wl...se...g.e.spldvlaalLekklalepgerDlvvlqhefgie.sdgkkkekktstlvgy.deegssamaktvGvpaaiaaklildgki 236
                    +  w+   s+   +   +pld+l+a+Le+k++++p+erD+v+lqh+f+ie +dg++ e++tstlv+y d++g+samak vGvp+++a+k++ldg+i
    EEA20279.1 321 AGlrWIglfSDdliTpRnNPLDTLCATLEQKMQYGPEERDMVMLQHKFEIEnKDGSR-ETRTSTLVEYgDPKGYSAMAKLVGVPCGVAVKFVLDGTI 416
                   4455666553246634347*************************************8.**********9899************************* PP

                   TSSEEEEGGGS.CHHHHHHHHHHHHHC CS
  Sacchrp_dh_C 237 kkrGvvtpeelvdpeiyeplleeLeke 263
                   +++Gv++p   ++ e++ pl++ L++e
    EEA20279.1 417 SEKGVLAP---MSMELCAPLIKTLKEE 440
                   ********...7779*********987 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.4   1.2   3.8e-28   4.6e-25       1     130 []      10     124 ..      10     124 .. 0.97

  Alignments for each domain:
  == domain 1  score: 88.4 bits;  conditional E-value: 3.8e-28
                      EEEE--SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHHHTTSSEEEE-SSGGGHHHHHHHHHHHT- CS
  Sacchrp_dh_NADP   1 vliiGaGsvGqavaellarhfdvdaeitvadrskeklealaakalgvrfeaialdaenyeavLaallkegdlvvnlsppissldvlkaCietgv 94 
                      vl++G+G+v+++++++l + + v  e+tva r+++++++la+   g+  +ai+ld+++ +a L++ l++ dlv++l+p++++++v+ka+i+t+ 
       EEA20279.1  10 VLLLGSGFVAKPTVDVLDQAG-V--EVTVAARNLNNAQKLAS--GGKHTKAISLDVNDAAA-LDKELEKVDLVISLIPYTYHAQVIKAAIRTKK 97 
                      79*****************98.5..7**************96..9****************.******************************** PP

                      EEEESS-BCGCCSCHCCSHHHHHTHHHHHHCTSEEE CS
  Sacchrp_dh_NADP  95 hyvdtsiskeertnyalreavlklkekakeagvtav 130
                      ++v+ts+         +++a+ +l+++ak+ag+t++
       EEA20279.1  98 NVVTTSY---------VSPAMQELEADAKKAGITVM 124
                      *******.........******************97 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.8   0.4     9e-10   1.1e-06       9      82 ..       4      79 ..       1     116 [. 0.85

  Alignments for each domain:
  == domain 1  score: 28.8 bits;  conditional E-value: 9e-10
                  ..TT-EEEEES-SHHHHHHHHHHHCCT-CEEEEEESSHHHHHHHHHHHT.ET-EEEEGCG...HHHHHHT-SEEEE- CS
  Shikimate_DH  9 slkekkvlliGaGemaelvakhLlakgvkkvvvaNRtlerakelaeelkgeeiealklee...lkellaeadvvisa 82
                  +++++kvll+G G +a+ ++  L ++gv+ v+va R+l++a++la+  k++++  l++++   l++ l+++d+vis 
    EEA20279.1  4 DVAGSKVLLLGSGFVAKPTVDVLDQAGVE-VTVAARNLNNAQKLASGGKHTKAISLDVNDaaaLDKELEKVDLVISL 79
                  67899***********************9.***************9877666655555542228899*******985 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.6   0.5   3.8e-09   4.6e-06       2      69 ..      14      92 ..      14     158 .. 0.78

  Alignments for each domain:
  == domain 1  score: 26.6 bits;  conditional E-value: 3.8e-09
                    TTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHHCT.TTCEEEE--TT-CCHHHHHHTT-SEEEES-...........- CS
  NAD_binding_10  2 AtGkvGrllvkellargghevtalvRnpeklaeleae.eglevvegdvtdvedlaealkgadaVvsal...........g 69
                    ++G v++  v+ l ++ g+evt+ +Rn + +++l++  ++++++++dv+d+++l + l+ +d V+s +           +
      EEA20279.1 14 GSGFVAKPTVDVLDQA-GVEVTVAARNLNNAQKLASGgKHTKAISLDVNDAAALDKELEKVDLVISLIpytyhaqvikaA 92
                    68999*****988888.6**************9995548999************************99665555444431 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.1   0.4   6.5e-08   7.8e-05       4      88 ..       4      99 ..       3     109 .. 0.80

  Alignments for each domain:
  == domain 1  score: 23.1 bits;  conditional E-value: 6.5e-08
  NAD_binding_7  4 dlkgkkvlvvGgGevAarkvrklleagakvtvvapevkeele........elvklaeeel...ekdlegadlviaatddrelneriaeaakarril 88
                   d+ g kvl+ G G vA   v  l +ag +vtv a +++++ +        + ++l  +++   +k+le++dlvi  ++ +   + i +a+++++ +
     EEA20279.1  4 DVAGSKVLLLGSGFVAKPTVDVLDQAGVEVTVAARNLNNAQKlasggkhtKAISLDVNDAaalDKELEKVDLVISLIPYTYHAQVIKAAIRTKKNV 99
                   67899*******************************865555777887666666654443345999***********9888888787777765544 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   1.0   1.1e-07   0.00013      25      98 ..       4      79 ..       2      97 .. 0.91

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 1.1e-07
                 CB---EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHHHHHHHHH..TTTCECEEHCHHHHHHHHHHHH-SEEEE- CS
  AlaDh_PNT_C 25 gvepakvlviGgGvaGlqAiatakglgakVtvlDvrparleqles..lgakfvevlksqeellaeavkeadvvigt 98
                 +v+ +kvl +G G +    + +  + g +Vtv   + + +++l s   + k +++  +++++l+++++++d+vi+ 
   EEA20279.1  4 DVAGSKVLLLGSGFVAKPTVDVLDQAGVEVTVAARNLNNAQKLASggKHTKAISLDVNDAAALDKELEKVDLVISL 79
                 57789****************************************8877888999*******************84 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.1   1.1e-06    0.0013       6     104 ..      14     111 ..      10     119 .. 0.79
   2 ?   -2.3   0.0         2   2.4e+03      95     124 ..     286     315 ..     283     320 .. 0.86

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 1.1e-06
                 TTSHHHHHHHHHHHHCTSEEEEEES-.STTTTCHHCHHC..EEEE--TT-HHHHHHHHHHHT-SEEEE--S---HHHHHHSHHHHHHHHTHHHHHHHHH CS
   Epimerase   6 atGfiGsalvkallekgyevigldrl.ssasntarledl..elveldltdrsalerlfkeeqpdavihlAavggvaassedpadfieknlqgtlnllea 101
                 ++Gf+ + +v+ l ++g+ev++ +r+ ++a++ a+   +  + + ld+ d++al++ ++  ++d vi l    +++a+++++a   +kn++ t  +  a
  EEA20279.1  14 GSGFVAKPTVDVLDQAGVEVTVAARNlNNAQKLASGG-KhtKAISLDVNDAAALDKELE--KVDLVISL-IPYTYHAQVIKAAIRTKKNVVTTSYVSPA 108
                 47*****************777776604444444443.358******************..9******9.66677777888888888898888887777 PP

                 HHH CS
   Epimerase 102 ark 104
                 +++
  EEA20279.1 109 MQE 111
                 765 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 2
                 HHHHHHHHHHHTCTEEEEEEEGGGGTSCSS CS
   Epimerase  95 tlnlleaarkagvkrllflsSsevYGkdae 124
                 t +++ a ++++++ l+ +sS +++ +++e
  EEA20279.1 286 TKKIIGATSDKELDLLWAISSKTTFADNDE 315
                 78899999999999999****999999887 PP

>> NAD_binding_3  Homoserine dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   1.4   3.7e-06    0.0044       1     114 [.      14     123 ..      14     126 .. 0.81

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 3.7e-06
                    --SHHHHHHHHHHHH---SSEEEEEEEEESS.EEE-TTHHHHHT--CB---HHHHHHHH....S-EEEEE-S--HHHHTTHHHHHHTTEEEE-S-- CS
  NAD_binding_3   1 GlGaiGsavleqlkrqqseielelvavadrd.sllskdrkallasealtldlddliahl....dpdvvVEcasseavaelvlkaLkagkdvvtank 91 
                    G G +++ +++ l++   e     v va r+   ++k +     ++a+ ld+ d +a      ++d+v+ + ++++ a+++ +a++ +k+vvt + 
     EEA20279.1  14 GSGFVAKPTVDVLDQAGVE-----VTVAARNlNNAQKLASGGKHTKAISLDVNDAAALDkeleKVDLVISLIPYTYHAQVIKAAIRTKKNVVTTSY 104
                    7899999999999999987.....5566666445556677777778888888887774377878*******************************8 PP

                    CGGG-HHHHHHHTSSSTTS--.E CS
  NAD_binding_3  92 galadealyeeLreaaeangaki 114
                       a     +eL + a+++g ++
     EEA20279.1 105 VSPA----MQELEADAKKAGITV 123
                    8877....888888888888776 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.6   3.6e-06    0.0043       6      84 ..      14      98 ..      10     104 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 3.6e-06
                TTSHHHHHHHHHHHHHT-EEEEEES-S-SHHHHHHHHSTTEE..EES-TT-HHHHHHHHTT-SEEEE---GG......S-HHHHHHH CS
        NmrA  6 aTGrqGksvvrallkaghkvralvRdtkselakslkeaGvel..vkgdlddkeslvealkgvdvvfsvtgfy......skeiedgkk 84
                ++G  +k  v++l +ag +v +  R+++  +a++l++ G  +  ++ d++d + l++ l++vd+v+s ++++      ++ i+  k+
  EEA20279.1 14 GSGFVAKPTVDVLDQAGVEVTVAARNLN--NAQKLASGGKHTkaISLDVNDAAALDKELEKVDLVISLIPYTyhaqviKAAIRTKKN 98
                689999999*****************96..6899999997663269999********************977765555555555555 PP

>> GFO_IDH_MocA  Oxidoreductase family, NAD-binding Rossmann fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.1   1.2e-05     0.014       2      91 ..       9     101 ..       8     125 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.2e-05
                   EEEEETTSHHHHHHHHHHHHTTTTEEEEEEECSSHHHHHHH........HHHTTHE.EESSHHHHHTCT.TESEEEE-S-GGGHHHHHHHHHHTT-E CS
  GFO_IDH_MocA   2 rvaiiGaGkigskhlrplnesqrleevvalldpdaeraeav........aesfgve.aysdleelladp.eidavivatpngtheelakaaleagkh 88 
                   +v++ G+G+++++ +  + ++  + ev+ +  ++ ++a+++        a     +  ++d ++l ++  ++d+vi  +p + h++++kaa++ +k+
    EEA20279.1   9 KVLLLGSGFVAKPTV-DVLDQ-AGVEVT-VAARNLNNAQKLasggkhtkAI----SlDVNDAAALDKELeKVDLVISLIPYTYHAQVIKAAIRTKKN 98 
                   688999999999999.55554.466666.5666677777775686443333....3444555555554359*************************9 PP

                   EEE CS
  GFO_IDH_MocA  89 vll 91 
                   v+ 
    EEA20279.1  99 VVT 101
                   985 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.2   1.4e-05     0.016       1      97 [.       9     103 ..       9     117 .. 0.85

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 1.4e-05
                     EEEEETTTSHHHHHHHHHHHCTSSEEEEEEEESTTTTTSBHHHHSGGGTTTECEBEEE..GGGGGCTT-SEEEE-SCHHHHHHHHHHHHHTTSEE CS
  Semialdhyde_dh   1 kvaivGatGyvGqellrlLeehpevelvvllsssrsaGkklaeavkaleegkdlkved..vdeeelkevdivflalpagvskelapklaeagvkv 93 
                     kv ++G +G v +  + +L++   ve++v++  + ++ +kla+  k  ++   l v+d  + ++el++vd+v++  p  +++++ ++++ ++  v
      EEA20279.1   9 KVLLLG-SGFVAKPTVDVLDQ-AGVEVTVAAR-NLNNAQKLASGGK-HTKAISLDVNDaaALDKELEKVDLVISLIPYTYHAQVIKAAIRTKKNV 99 
                     688999.************98.5677777544.4458888888877.6778888888876777888**********************9999999 PP

                     EESS CS
  Semialdhyde_dh  94 iDls 97 
                     +  s
      EEA20279.1 100 VTTS 103
                     8765 PP

>> IlvN  Acetohydroxy acid isomeroreductase, NADPH-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.4   2.5e-05     0.029       4      83 ..       7      95 ..       4     106 .. 0.74
   2 ?   -1.3   0.0       1.2   1.4e+03     118     149 ..     117     149 ..     112     164 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 2.5e-05
                TS-EEEES-SHHHHHHHHHHHHTT--EEEEE-TT-HHHHHH......HHTT-EEEEH...HHHHHT-SEEEE-S-HHHHHHHHHHHTGG CS
        IlvN  4 gkkiaviGyGsqGhaqalnlrdsgldvvvglregsksvkkA......keegfevltv...aeavkkadvvmiliPDelqkevyeeeiep 83
                g k+ ++G G  ++     l ++g++v+v+ r+ ++  k A      k+ +++v ++   ++  +k d+v+ liP +++++v++++i+ 
  EEA20279.1  7 GSKVLLLGSGFVAKPTVDVLDQAGVEVTVAARNLNNAQKLAsggkhtKAISLDVNDAaalDKELEKVDLVISLIPYTYHAQVIKAAIRT 95
                7799999999999******************998865555511111133344444431113445789*****************99975 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.2
                 SS-SHHHHHHHHTT----EEEEEEE.-SSS-HH CS
        IlvN 118 kgpGhlvreeyeegkGvpaliaveq.dasgkak 149
                 k  G +v++e     G+ +l+av+   + ++a 
  EEA20279.1 117 KKAGITVMNEIGLDPGIDHLYAVKTiTEVHEAG 149
                 678999999999999999999998412334444 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   1.1   3.1e-05     0.037       1     110 [.      10     121 ..      10     125 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 3.1e-05
                 EEEES-SHHHHHHHHHHHHTTEEEEEEESSHHHHHHHHHTT..SEEEES-TTSHHHHHHTTGGGESEEEE-SSSH..HHHHHHHHHHHHHTSSSEEEEE CS
      TrkA_N   1 iiiiGlGrvGrslaeeLseggkdvvvidkdeerveelreeg..levvvgdatdeevLeeagiekadaviaatgdd..eanilavllakelnpkkkiiar 95 
                 ++++G G v++  ++ L ++g +v+v  ++ +++++l+  g  ++++  d+ d ++L++ ++ek+d+vi +++    +  i a+   k+ n   + ++ 
  EEA20279.1  10 VLLLGSGFVAKPTVDVLDQAGVEVTVAARNLNNAQKLASGGkhTKAISLDVNDAAALDK-ELEKVDLVISLIPYTyhAQVIKAAIRTKK-NVVTTSYVS 106
                 57899999***********6646***************9998788************98.7***********97632333333333333.333444454 PP

                 ESSGGGHHHHHHHTT CS
      TrkA_N  96 aqdpehaellkklga 110
                    +e +  +kk+g+
  EEA20279.1 107 PAMQELEADAKKAGI 121
                 455555555555665 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.1   0.00011      0.13      30     104 ..       1      85 [.       1      97 [. 0.76

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00011
                   SBS-GTTSEEEEES-SHHHHHHHHHHHHTT-EEEEESSSHHHHH.........CHHHHTC.EECSHHHHHHH-SEEEE-S--STT CS
  2-Hacid_dh_C  30 lgkelsgktvGiiGlGrIGqavakrlkafgmkviaydrskkkee.........eeeelgv.elvsleellaesDivslhlpltpe 104
                   +gk+++g++v ++G G +++ + ++l + g++v++  r+ ++ +         ++ +l v + + l++ l++ D v+  +p+t +
    EEA20279.1   1 MGKDVAGSKVLLLGSGFVAKPTVDVLDQAGVEVTVAARNLNNAQklasggkhtKAISLDVnDAAALDKELEKVDLVISLIPYTYH 85 
                   5899**********************************99977755555543323333333455677777777777777777655 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.1   0.00016      0.19       5      98 ..      14     104 ..      10     116 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00016
   3Beta_HSD   5 gaGFlGralvkeLvrleelkevrvlDlrespelleelskvnvkkviegDvtdkdkleealegvdvvihlaslvdvagkltedeimkvnvkGTrn 98 
                 g+GF+ +  v  L +++   +v +  l++ ++l   +s  + +k i  Dv+d++ l++ le+vd+vi l  ++  a++++     k nv  T  
  EEA20279.1  14 GSGFVAKPTVDVLDQAGVEVTVAARNLNNAQKL---ASGGKHTKAISLDVNDAAALDKELEKVDLVISLIPYTYHAQVIKAAIRTKKNVVTTSY 104
                 789999999999999986555555555555555...5555555589*********************998888888877777777777766655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (450 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       432  (0.024095); expected 358.6 (0.02)
Passed bias filter:                      395  (0.0220313); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3040.96
//
Query:       EEA20280.1  [L=596]
Description: transcription regulator (RTG2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.5e-40  138.2   0.0    2.2e-39  135.6   0.0    2.0  1  Ppx-GppA         Ppx/GppA phosphatase family
  ------ inclusion threshold ------
       0.16   12.0   0.0       0.35   10.9   0.0    1.6  1  Semialdhyde_dhC  Semialdehyde dehydrogenase, dimerisation dom


Domain annotation for each model (and alignments):
>> Ppx-GppA  Ppx/GppA phosphatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  135.6   0.0   2.5e-43   2.2e-39      10     282 ..      55     364 ..      44     366 .. 0.86

  Alignments for each domain:
  == domain 1  score: 135.6 bits;  conditional E-value: 2.5e-43
                 EEEEEEEEEE--CCCC.CHCCS....SC-HHHHHHHHHHHHHHHHHCCCTTG..CCEEEEEEHHHHHSTTHHHHHHHHCCCCSS-EEEE-HHHHHHHHH CS
    Ppx-GppA  10 lqivarekrkvrLaeg.lnesg....rlqeeaiertisaLkefaellqkfkv..envrvVATsalRdavNadeFlarvkkevglkveiisgeeEarliy 101
                 +++++ ++++++L+++ +++++    ++++ +i+  i a+ +f   + +f+v  + vrvVAT+a+R a+N++e ++ +++++g++ve+++  eE+ l++
  EEA20280.1  55 IPTLHTQRVGISLYDAqYDSKTgskiPVPRSIIQSIIGAILRFQATCVQFGVpsSHVRVVATEATRTAINSKEIVESIETRTGYQVELLEKSEEGLLGA 153
                 7899***************9999*999*************************999******************************************** PP

                 HHHHHHT---SSEEEEEEETTEEEEEEEET......TEEEEEEEES--CCHHHHHH..SGCCC--HHHHHHHHHHHHHH.............CTTTHHH CS
    Ppx-GppA 102 lgvvssllekgrglviDiGGGStElvlgee......kevsklvSlplGavrlterf..ltddpltkeeveaarkaveke.............leevkde 179
                 lg++s + ++ +gl  D+GGGSt+l ++ +        ++ ++S p+Ga+ l ++   l+++   ke+++a+ k+ +++             + +++ e
  EEA20280.1 154 LGIASGY-SDIEGLAMDLGGGSTQLTWVVShgsvlnISPQGSISFPYGAGALSRKLeeLKKGKSKKEAKQAIDKLNQEMkdnflnaytkleiPDRLAHE 251
                 *******.*********************9888887789999**********99863355555555555555554444434443333443555566666 PP

                 HCCCE...HHCCCCCCCHCCHHCHHHHHHCT.S.......SCEEEHHHHHHHHHHHCTSSCHHHHHSTTS-CCHHCTHHHHHHHHHHHHHHCT-S..EE CS
    Ppx-GppA 180 vkkeg...ewtrlvgtsgtisalaeltelhgek.......gyeitaeeleeliekllqlkkeeelklagvsdeRadvivagalilsavlealeie..av 266
                 +k++g     ++++g +g + +l++l +++g +       gy+  + e+ +  e+l ++   +  +++ vsd+R ++++a+a  +  ++e l+    +v
  EEA20280.1 252 AKENGgfrMYISGGGFRGWGYLLLYLHQTKGRNypisiinGYRAGRDEFAK-TETLKEIA-RTADRIFRVSDRRRQQVPAVAFLINVLAESLPHGikEV 348
                 66666999999*******************988999999999999999987.58888888.7789***************************96445** PP

                 EEES--HHHHHHHHHH CS
    Ppx-GppA 267 iisegalrEGvlysll 282
                  +++g++rEG+l++ l
  EEA20280.1 349 FFCQGGVREGILFQQL 364
                 ************9987 PP

>> Semialdhyde_dhC  Semialdehyde dehydrogenase, dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   3.9e-05      0.35      94     152 ..      97     157 ..      78     184 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 3.9e-05
                      EEEEEEEESBSSEEEEEEEEEESSSHHHHHHHHHHHHCS..TTEEEEESSHCHHSSHHHHT CS
  Semialdhyde_dhC  94 vsatcvrVPvlrGhseavtiklklkdveveeveellaaa..pevkvvvneeedrPtpaava 152
                        atcv+ +v ++h   v ++++++++  +e+ e +++    +v++ +++ee  + ++  a
       EEA20280.1  97 FQATCVQFGVPSSHVRVVATEATRTAINSKEIVESIETRtgYQVELLEKSEEGLLGALGIA 157
                      349**********************************995555555555566666655555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (596 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       864  (0.0481901); expected 358.6 (0.02)
Passed bias filter:                      745  (0.0415528); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.29s 00:00:00.96 Elapsed: 00:00:00.43
# Mc/sec: 4147.08
//
Query:       EEA20281.1  [L=387]
Description: prenyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.4e-79  264.2   0.0    1.4e-78  263.5   0.0    1.3  1  Prenyltransf  Putative undecaprenyl diphosphate synthase


Domain annotation for each model (and alignments):
>> Prenyltransf  Putative undecaprenyl diphosphate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  263.5   0.0   7.8e-83   1.4e-78       1     220 [.      47     352 ..      47     355 .. 0.81

  Alignments for each domain:
  == domain 1  score: 263.5 bits;  conditional E-value: 7.8e-83
                   EE--HHHHHHHTT.S-HHHHHHHHHHHHHHHHHHHHHTT-SEEEEEEEEGGGGGS-HHHHHHHHHHHH...HHHHHHHHHHHHHT.TEEEEEESSGG CS
  Prenyltransf   1 imDGNrRwAkkrgleereeGhkaGaealkeilelclelgvkvvtvYafSteNfkRskeevdalmellk...eellkeelkellke.gvrvrviGdle 93 
                   +mDGNrR+Ak++g+e+ e Gh+ G+eal++ile+c+++gvkvvt+YafS+eNf+Rs+ ev+ lm++++    +l++++  ++l++ g+++r++G+++
    EEA20281.1  47 VMDGNRRFAKTHGIETIE-GHHLGFEALARILEVCYKSGVKVVTIYAFSIENFNRSQFEVNGLMDMANvklAQLAQHG--DILDRyGASIRFLGRKD 140
                   8************99988.************************************************97777788888..888888*********** PP

                   GS-HHHHHHHHHHHHHHT.TTTSEEEEEEEEE-HHHHHHHHHHHHHHTT................................................ CS
  Prenyltransf  94 llpedvlealekaeeatkknnkklvlniavnYgsrdeiveavrelvkeks............................................... 143
                   ll++dv +a+++a+e t++n +  +lni+++Y+srde+++a+r++v ++s                                               
    EEA20281.1 141 LLRPDVVAAVDRAVELTSRNGD-KILNICCPYTSRDEMTQAIRQTVVDYStpleatrvnggrkpfseshiasniraqtlqnmkdqdssadsdsasaf 236
                   ******************7666.9*********************9998878887778788777777777777777666666655555555444444 PP

                   ........SSSGGGHSH........................................HHHHCTSTT..TSSS-SEEEEESS--S-TTSSTTTTTT-E CS
  Prenyltransf 144 .......eekkkeeide........................................etlekhlytakalpdpDlliRtsGeeRlSnFllwqlayse 193
                          +                                                 +tl++++yt  + p++D+l+RtsG+eRlS+F+lwq ++++
    EEA20281.1 237 sqdedngS--------PivnqanrvydssssfsssttlhlgqtagspdylssesitsQTLTDRMYTGGN-PPIDILVRTSGVERLSDFMLWQ-CHED 323
                   44443330........03333444444444444444444444444444555545544*********777.**********************.6655 PP

                   ..EEEESSSGGG--HHHHHHHHHHHHHCH CS
  Prenyltransf 194 ..lyfldvlWPdfskedllealleyqkre 220
                     + fldvlWP+f+ +++l++l+++q+r 
    EEA20281.1 324 teIAFLDVLWPEFDLWHFLPVLWKWQRRI 352
                   58************************995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (387 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       590  (0.0329076); expected 358.6 (0.02)
Passed bias filter:                      448  (0.0249875); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.49
# Mc/sec: 2372.76
//
Query:       EEA20282.1  [L=737]
Description: glycerol-3-phosphate acyltransferase Sct1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.5e-09   36.9   0.0    0.00079   19.1   0.0    2.3  2  Acyltransferase  Acyltransferase
  ------ inclusion threshold ------
      0.011   16.1   0.2      0.058   13.8   0.0    2.1  2  PRA-PH           Phosphoribosyl-ATP pyrophosphohydrolase


Domain annotation for each model (and alignments):
>> Acyltransferase  Acyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   1.1e-06    0.0098       8      76 ..      39     110 ..      32     130 .. 0.80
   2 !   19.1   0.0   8.8e-08   0.00079      87     134 ..     228     281 ..     214     282 .. 0.86

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1.1e-06
  Acyltransferase   8 enlpekgpailvaN.Hqsy.lDvlllwlllyksn.gprnvviiakkellsipllgflmrllgfifidR..ksna 76 
                       ++p+ gp+i+va  H    +D l+l+ ++  ++ g+r  ++ia k+ ++ +++g l+r +g++++ R  ++++
       EEA20282.1  39 WKVPKRGPLIIVAApHANQfVDSLILMRAVR-REiGRRISWLIAEKS-FKRKFIGLLSRGIGAVPVARamDNMK 110
                      56888899888765499989********995.555978889999999.666*****************443333 PP

  == domain 2  score: 19.1 bits;  conditional E-value: 8.8e-08
  Acyltransferase  87 e.lleegklvviFPEGtrsregellpfkkGlvrlaakak.....kgvpivPvai 134
                        +l++g  ++iFPEG+     ellp k+G++ +a+         g+ ivP+++
       EEA20282.1 228 FgRLSHGGCIGIFPEGGSHDRPELLPLKAGVAIMALGSLaenpdSGLKIVPCGM 281
                      24899*****************************99888899999999999987 PP

>> PRA-PH  Phosphoribosyl-ATP pyrophosphohydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   6.5e-06     0.058      33      76 ..     302     345 ..     300     351 .. 0.88
   2 ?   -1.0   0.0      0.27   2.4e+03      18      42 ..     562     587 ..     557     644 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 6.5e-06
                 HHHHHHHHHT-SCHHHHHHHHHHHHHHHHHHHHHHCT--CHHHH CS
      PRA-PH  33 EEavElleaasegdlaeladelaDllYvtygllvllGidldavf 76 
                 E+  El+e  ++g++ e + el D++Y+++ ++  +G d + ++
  EEA20282.1 302 EVPRELVEKYKRGERREAVGELLDTIYHALLAVTVNGPDYETLM 345
                 5568**************************99999998777665 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.27
                 --.-HHHHHHHHHHHHHHHHHHHHHT CS
      PRA-PH  18 as.taelaslraaligEEavElleaa 42 
                 +  t  ++++r+a +  E++E++ + 
  EEA20282.1 562 SAnTLVKLRERRAELSQEVTEVINTL 587
                 44456666678888999999998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (737 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       457  (0.0254894); expected 358.6 (0.02)
Passed bias filter:                      355  (0.0198003); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.26s 00:00:00.85 Elapsed: 00:00:00.42
# Mc/sec: 5328.05
//
Query:       EEA20283.1  [L=460]
Description: ubiquinol-cytochrome c reductase complex 17 kd protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.4e-25   89.2   5.9    1.4e-25   89.2   5.9    2.0  1  UCR_hinge        Ubiquinol-cytochrome C reductase hinge prote
    0.00083   19.5   0.0      0.012   15.7   0.0    2.2  2  Vps36_ESCRT-II   Vacuolar protein sorting protein 36 Vps36
     0.0021   17.5  16.5     0.0039   16.6  16.5    1.4  1  CobT             Cobalamin biosynthesis protein CobT
      0.007   14.9  15.0      0.013   14.0  15.0    1.3  1  Mpp10            Mpp10 protein
  ------ inclusion threshold ------
      0.045   12.6   1.2      0.053   12.3   1.2    1.2  1  SAPS             SIT4 phosphatase-associated protein
      0.047   14.0   0.0      0.083   13.3   0.0    1.4  1  bPH_3            Bacterial PH domain
       0.11   12.3   0.0       0.25   11.2   0.0    1.6  1  GRAM             GRAM domain
        0.2   11.5  13.4      0.055   13.3  10.4    1.6  2  RR_TM4-6         Ryanodine Receptor TM 4-6
       0.43   10.4   5.0       0.88    9.4   0.0    2.9  3  Folliculin       Vesicle coat protein involved in Golgi to pl
       0.48   10.7  15.0       0.14   12.4  10.7    2.1  2  RNA_pol_3_Rpc31  DNA-directed RNA polymerase III subunit Rpc3
       0.86    8.9  13.6        1.5    8.1  13.6    1.3  1  BUD22            BUD22
          2    7.1  13.1          4    6.1  13.1    1.4  1  Tim54            Inner membrane protein import complex subuni
        2.4    8.1  30.3        4.5    7.2  30.3    1.3  1  Merozoite_SPAM   Merozoite surface protein (SPAM)
        2.5    8.3   7.0        7.1    6.8   7.0    1.7  1  CPSF100_C        Cleavage and polyadenylation factor 2 C-term
        3.4    5.8  18.0        4.9    5.2  18.0    1.1  1  Nop14            Nop14-like family
        4.3    6.7   8.6        1.1    8.7   5.6    1.4  2  SpoIIP           Stage II sporulation protein P (SpoIIP)
        5.3    7.5   9.6       0.43   11.0   4.4    1.9  2  RNA_pol_Rpc4     RNA polymerase III RPC4
        5.3    7.5  33.3         14    6.1  33.3    1.7  1  Prothymosin      Prothymosin/parathymosin family
        6.6    6.1  18.9        1.7    8.0  15.5    1.6  2  SDA1             SDA1


Domain annotation for each model (and alignments):
>> UCR_hinge  Ubiquinol-cytochrome C reductase hinge protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.2   5.9   1.5e-28   1.4e-25       1      66 []     391     460 .]     391     460 .] 0.98

  Alignments for each domain:
  == domain 1  score: 89.2 bits;  conditional E-value: 1.5e-28
   UCR_hinge   1 DpkeklreeCeekekCkklkkhyeeCveRVksrse....aeteedCveelfdlvhcvdhCvapklfkkLK 66 
                 D k++l+e C+++  C+++k+h++eCveRV++++e    + ++edCvee+f+l+hc+++C+apkl+k+L+
  EEA20283.1 391 DIKPALEEDCANSTVCAPFKHHFDECVERVTRAQEegdsTGPKEDCVEEFFHLQHCATQCAAPKLWKSLR 460
                 89***********************************99999*************************996 PP

>> Vps36_ESCRT-II  Vacuolar protein sorting protein 36 Vps36
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.0      0.46   4.3e+02      35      54 ..       4      20 ..       1      33 [. 0.75
   2 !   15.7   0.0   1.3e-05     0.012      35      70 ..      44      80 ..      35      91 .. 0.79

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.46
  Vps36_ESCRT-II 35 rqnGrlyLTthriiyvdsad 54
                     ++G + L +++iiy    +
      EEA20283.1  4 SKEGFVRLPNEHIIYT---S 20
                    5789999********6...3 PP

  == domain 2  score: 15.7 bits;  conditional E-value: 1.3e-05
  Vps36_ESCRT-II 35 rqnGrlyLTthriiyvdsadpkk.eslslelklvesv 70
                     ++G lyLT++ri+y++s+ +++ +s +++l ++ ++
      EEA20283.1 44 SSSGCLYLTNQRIVYLPSQPNERmQSFTVPLLNLHDS 80
                    679***************9888625678888776665 PP

>> CobT  Cobalamin biosynthesis protein CobT
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6  16.5   4.1e-06    0.0039     175     264 ..     302     390 ..     296     403 .. 0.63

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 4.1e-06
        CobT 175 kdldrlaealeDqkaFaravrqlLqdldlaeesaeepeeedeeeeedeeeeeeeseeeeeegedddkeeqeeaaseeeeeededeesket 264
                 ++l  l+e ++ +  F ++  +l +   lae  ae+p  e +e+  +e+ee+ e+++e e +e++ ++e+ee ++eeeeee+e+ee++ +
  EEA20283.1 302 TQLRSLSELTRSEMGFTDFFSDLVSGFGLAEAHAEAPPAEHDESVAEEQEEKTEESTE-EPEEAEPEAEAEEVEEEEEEEEEEEEEEEPQ 390
                 68999*************************9999998888877766655555554443.2222222223333333333333333223322 PP

>> Mpp10  Mpp10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.0  15.0   1.3e-05     0.013     230     304 ..     312     391 ..     303     434 .. 0.50

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1.3e-05
       Mpp10 230 aedlkYeDFFdkpee.....kkkkkkkkkdeeeadeeeedeeee...eeeeeeeeeeeeeedleeedeeeeeeeeeedeeeke 304
                  +++ + DFF +  +     + ++ +   +e++++  ee+ee++   +ee ee+e e e e++eee+eeeeeeeeee+   ++
  EEA20283.1 312 RSEMGFTDFFSDLVSgfglaE-AHAEAPPAEHDESVAEEQEEKTeesTEEPEEAEPEAEAEEVEEEEEEEEEEEEEEE--PQD 391
                 57899*******999999862.33333333333333333333321112222222222222222222222222222222..222 PP

>> SAPS  SIT4 phosphatase-associated protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   1.2   5.6e-05     0.053     279     344 ..     332     401 ..     208     453 .. 0.68

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 5.6e-05
        SAPS 279 esaesedltdkdedvsleesksakdenkesdesesdtaeesseed.eddasseesalaeeteeklr...k 344
                 e+++++  +++de+v++e++++++++++e++e+e + + e++ee+ e+++++ee+ + ++ +++l+    
  EEA20283.1 332 EAHAEAPPAEHDESVAEEQEEKTEESTEEPEEAEPEAEAEEVEEEeEEEEEEEEEEEPQDIKPALEedcA 401
                 4444455566677777777777777666666655554444444430334444444455555555554442 PP

>> bPH_3  Bacterial PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   8.8e-05     0.083       4      61 ..      13      85 ..      11      93 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 8.8e-05
       bPH_3  4 dEkilyltkgqinak...............ldkpglivvTnkRiifldpkmfggkdfeeipYksIksvdlkkg 61
                +E+i+y+    +                  ++++g++ +Tn+Ri++l +++ +++++  +p+ ++ + ++++ 
  EEA20283.1 13 NEHIIYTSPPRTALSlkppnswkgredfsiTSSSGCLYLTNQRIVYLPSQPNERMQSFTVPLLNLHDSHVSAP 85
                667777664444333446667777777888999******************9999999999999999888765 PP

>> GRAM  GRAM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   0.00027      0.25      28      62 ..      36      77 ..       4      94 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00027
                .......SEEEEEEEEESSEEEEEE-STT---E.EEEEGGGE CS
        GRAM 28 g......gpvqGrlyltnyrlcFrskplgsskk.vvlpladi 62
                g         +G lyltn+r+++ ++ ++  ++ +++pl  +
  EEA20283.1 36 GredfsiTSSSGCLYLTNQRIVYLPSQPNERMQsFTVPLLNL 77
                15555556789*****************99999999998666 PP

>> RR_TM4-6  Ryanodine Receptor TM 4-6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       6.2   5.8e+03      71      84 ..     213     226 ..     186     243 .. 0.53
   2 ?   13.3  10.4   5.8e-05     0.055      64     144 ..     311     391 ..     297     422 .. 0.45

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 6.2
                 XXXXXXXXXXXXXX CS
    RR_TM4-6  71 gDlseteaeesptp 84 
                  ++++++++e+++ 
  EEA20283.1 213 EEVQQQSVAEELEE 226
                 33333333333221 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 5.8e-05
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXX....XXXXXXXXXXXXXXXXXXX.XXX...XXXXXXXXXXXXX..........XXXXXXX CS
    RR_TM4-6  64 kkseagLgDlseteaeesptpelkkkla....eeeeaeeekeeeeepeaeaeeka...daengekeekekekeeeekeseeeeeekkk 144
                 + se g++D++++ ++    +e++ +      +e++aee++e++ee+++e+ee++   +ae+ e+ee+e+       e+eeeeee + 
  EEA20283.1 311 TRSEMGFTDFFSDLVSGFGLAEAHAEAPpaehDESVAEEQEEKTEESTEEPEEAEpeaEAEEVEEEEEEE-------EEEEEEEEPQD 391
                 5677888888887776654322222222222233333333333333333332221000222222222221.......11112222121 PP

>> Folliculin  Vesicle coat protein involved in Golgi to plasma membrane transport
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.0   0.00094      0.88      90     173 ..     127     252 ..     123     257 .. 0.81
   2 ?    0.3   0.0       0.6   5.7e+02      19      45 ..     300     325 ..     286     333 .. 0.53
   3 ?   -0.5   1.7         1   9.7e+02     103     114 ..     370     381 ..     340     435 .. 0.55

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00094
  Folliculin  90 eafeklaaeiqalaeaelereskeeeassaassssa..............................................lkadgsglsrregssfs 142
                 ++fe++ +++q+++e+  +++s++ +a++++                                                     + + g+++ +++s++
  EEA20283.1 127 SNFERIKERLQQAVEHARDSDSASVQAQTSR----GvnftnvhldelpaydgpnassvspnqpinaaveppgretanttspaPVEPPPGYEEVQQQSVA 221
                 6788888888888888887777655433332....1345689***********************************9999855556667777777888 PP

  Folliculin 143 lskekylrrsksklkarsLaelvgdediFve 173
                  + e+ lrr ++++++ +L  lv+  +i++ 
  EEA20283.1 222 EELEEQLRRASTSVSNNKLSALVDTRNIYAL 252
                 888999999999999*************975 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.6
  Folliculin  19 rqaclrsLScEtlprasggpifFgDea 45 
                 +++ lrsLS+ t ++  g   fF D +
  EEA20283.1 300 NNTQLRSLSELTRSE-MGFTDFFSDLV 325
                 344445555444433.44444555555 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 1
  Folliculin 103 aeaelereskee 114
                 ae++ e+e++ee
  EEA20283.1 370 AEEVEEEEEEEE 381
                 122221111111 PP

>> RNA_pol_3_Rpc31  DNA-directed RNA polymerase III subunit Rpc31
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.1       1.1   1.1e+03      42      71 ..     203     232 ..     181     248 .. 0.82
   2 ?   12.4  10.7   0.00015      0.14     166     211 ..     342     388 ..     285     392 .. 0.59

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 1.1
  RNA_pol_3_Rpc31  42 slpvakplteeersqvslyrklreqihdgp 71 
                      + pv++p+  ee +q s  ++l+eq++++ 
       EEA20283.1 203 PAPVEPPPGYEEVQQQSVAEELEEQLRRAS 232
                      679999999999999999999999999875 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 0.00015
  RNA_pol_3_Rpc31 166 egkelleklkelaeeeddeeekkekedeeeee...eeeeddefdddded 211
                       ++++ e+ +e++ee  +e  ++e+e e e e   eeee++e ++++e+
       EEA20283.1 342 HDESVAEEQEEKTEESTEE--PEEAEPEAEAEeveEEEEEEEEEEEEEE 388
                      3334444444333333332..2222222222222122333333333333 PP

>> BUD22  BUD22
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1  13.6    0.0016       1.5     148     205 ..     337     402 ..     313     441 .. 0.42

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0016
       BUD22 148 kkkkkkkkkkkkkkeeeeeeesdkeeesedsedeekeeseddeeeeeededdedaee..........d 205
                 +  ++ +++ ++++ee+ ee++++ ee+e + +  +ee e++eeeeee+e++e+ ++          +
  EEA20283.1 337 APPAEHDESVAEEQEEKTEESTEEPEEAEPEAE--AEEVEEEEEEEEEEEEEEEPQDikpaleedcaN 402
                 222222222333333333122222222222222..233333333333333333333344434333440 PP

>> Tim54  Inner membrane protein import complex subunit Tim54
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1  13.1    0.0042         4     192     254 ..     337     396 ..     329     421 .. 0.51

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0042
       Tim54 192 kpeepeeeeaeeeeeeeeeekeeeeeeeeeeeeekeeekeeekeeeeeeeekekkkkvpkpyi 254
                 +p++++ e+++ee+ee++ee++ee ee+   e e+e+e+ ee+eeeeeeee+e++++  kp +
  EEA20283.1 337 APPAEHDESVAEEQEEKTEESTEEPEEA---EPEAEAEEVEEEEEEEEEEEEEEEPQDIKPAL 396
                 4444444444444444444444444444...22233333333333333333333445555544 PP

>> Merozoite_SPAM  Merozoite surface protein (SPAM)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2  30.3    0.0048       4.5      37     100 ..     339     392 ..     327     409 .. 0.45

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0048
  Merozoite_SPAM  37 akEnedvveeeeeedleekedeeeEteeeeteekneeeieeetedeedEeeveEeeekeeeedk 100
                     + E ++ v ee+ee+ ee  +e eE e     e++ ee+eee+e+ee+Eee+eE ++       
      EEA20283.1 339 PAEHDESVAEEQEEKTEESTEEPEEAE----PEAEAEEVEEEEEEEEEEEEEEEPQD------I 392
                     445555544444444444444444433....22333333333333333333333222......2 PP

>> CPSF100_C  Cleavage and polyadenylation factor 2 C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   7.0    0.0075       7.1      16      87 ..     325     396 ..     321     408 .. 0.49

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0075
   CPSF100_C  16 veglevatvtgeleieeeaeeaeeeekeeeeeeeeeeeeeeeaskkqklaeksekeaseeeseekkeslptl 87 
                 v+g+++a   +e  ++e++e+ +ee++e++ee++ee ee e++ + ++ +e++e+e++eee+ee ++  p l
  EEA20283.1 325 VSGFGLAEAHAEAPPAEHDESVAEEQEEKTEESTEEPEEAEPEAEAEEVEEEEEEEEEEEEEEEPQDIKPAL 396
                 556666666666665444333333333333333333333333333333344444555555555555555554 PP

>> Nop14  Nop14-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2  18.0    0.0052       4.9     342     397 ..     336     393 ..     316     439 .. 0.45

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.0052
       Nop14 342 a...taeeeeeededdfeedddlveseseeee.eeeeedeeeeedeeeeeeeeededdls 397
                 +    +++e++ +e++++ +++ +e  +e+e+ +e ee eeeee+eeee eeee+ +d +
  EEA20283.1 336 EappAEHDESVAEEQEEKTEESTEEP-EEAEPeAEAEEVEEEEEEEEEE-EEEEEPQDIK 393
                 12332223333333333333322222.2223312222222222222222.2222222222 PP

>> SpoIIP  Stage II sporulation protein P (SpoIIP)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.1   0.0       8.9   8.4e+03     109     126 ..     219     236 ..     211     245 .. 0.67
   2 ?    8.7   5.6    0.0011       1.1      27      70 ..     342     386 ..     308     428 .. 0.48

  Alignments for each domain:
  == domain 1  score: -4.1 bits;  conditional E-value: 8.9
      SpoIIP 109 eVGeeLaeeLekygisvi 126
                 +V+eeL+e+L +   sv 
  EEA20283.1 219 SVAEELEEQLRRASTSVS 236
                 467777777766555554 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.0011
      SpoIIP  27 sekeekekeeeeeeekeeeeeeeikkeekeeekekee.dseeeee 70 
                 ++++  e++ee++ee+ ee ee + + e+ee +e+ee ++eeeee
  EEA20283.1 342 HDESVAEEQEEKTEESTEEPEEAEPEAEAEEVEEEEEeEEEEEEE 386
                 222221111111111111111111111111111111111111111 PP

>> RNA_pol_Rpc4  RNA polymerase III RPC4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.2       6.8   6.4e+03      44      44 ..     211     211 ..     172     244 .. 0.47
   2 ?   11.0   4.4   0.00046      0.43      19      67 ..     342     390 ..     275     405 .. 0.47

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 6.8
  RNA_pol_Rpc4  44 e 44 
                   +
    EEA20283.1 211 G 211
                   1 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 0.00046
  RNA_pol_Rpc4  19 kavsaaeddkseaesqsaekakaeeeskaekasgaeaeekkskkksskk 67 
                   +++s ae++++++e++++e ++ae+e++ae+ +++e+ee++++++++++
    EEA20283.1 342 HDESVAEEQEEKTEESTEEPEEAEPEAEAEEVEEEEEEEEEEEEEEEPQ 390
                   2222222222222222233333333333333333333322222222222 PP

>> Prothymosin  Prothymosin/parathymosin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1  33.3     0.015        14      31      96 ..     336     399 ..     329     407 .. 0.58

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.015
  Prothymosin  31 dapangnaneengeeeadeeveeeeeeeeeeeeeeeeeeeegeeeegeeeeeeaegatvkraAede 96 
                  +ap  ++ +e   +ee++e++ee+ ee ee e e e ee e+eeee+eeeeee+e + +k a e++
   EEA20283.1 336 EAPPAEH-DE-SVAEEQEEKTEESTEEPEEAEPEAEAEEVEEEEEEEEEEEEEEEPQDIKPALEED 399
                  3443333.34.4444444444444444444554444455566666667788888999999998888 PP

>> SDA1  SDA1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.1         3   2.9e+03     216     243 ..     129     155 ..     127     170 .. 0.65
   2 ?    8.0  15.5    0.0018       1.7     126     179 ..     343     391 ..     317     440 .. 0.48

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 3
        SDA1 216 Faklkelraeaavkkqlesakrkkkkkk 243
                 F+++ke   ++av+++ +s++++ ++++
  EEA20283.1 129 FERIKERL-QQAVEHARDSDSASVQAQT 155
                 88888877.5667777666665544443 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0018
        SDA1 126 deeeieesdesedeeeeeeeeeekeekeeeeeeeeeeeeeeeeeeeeeekekkk 179
                 de  + e++e+++ee+ ee ee++ e e ee ee    eeeeeeeeeee+e ++
  EEA20283.1 343 DES-VAEEQEEKTEESTEEPEEAEPEAEAEEVEE----EEEEEEEEEEEEEPQD 391
                 222.222222222222222222222222222222....1111111111122222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (460 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1768  (0.0986112); expected 358.6 (0.02)
Passed bias filter:                      918  (0.051202); expected 358.6 (0.02)
Passed Vit filter:                       248  (0.0138323); expected 17.9 (0.001)
Passed Fwd filter:                        45  (0.0025099); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              19  [number of targets reported over threshold]
# CPU time: 0.88u 0.34s 00:00:01.22 Elapsed: 00:00:00.46
# Mc/sec: 2984.44
//
Query:       EEA20284.1  [L=508]
Description: cell surface receptor/MFS transporter (FLVCR), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.4e-28   99.8  31.6    1.4e-28   99.8  31.6    1.6  1  MFS_1       Major Facilitator Superfamily
    3.8e-09   35.6   1.2    3.8e-09   35.6   1.2    2.6  3  MFS_2       MFS/sugar transport protein
      1e-05   24.6   2.0      1e-05   24.6   2.0    2.8  4  MFS_1_like  MFS_1 like family
  ------ inclusion threshold ------
      0.042   13.9   3.3       0.49   10.5   0.3    3.1  2  DUF2798     Protein of unknown function (DUF2798)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.8  31.6   3.2e-32   1.4e-28       2     327 ..      81     405 ..      80     431 .. 0.83

  Alignments for each domain:
  == domain 1  score: 99.8 bits;  conditional E-value: 3.2e-32
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.....sslw.lllvlrvl 94 
                 +l+ +++++++ +++++ + + ae + +s+++i++l t++ ++++va+++++++ ++ G+r v++++ +l ++g ++   a     ++++ +++++ +l
  EEA20284.1  81 VLLNIVISWDWLTFSSISS-TSAEYFRVSEATINWLSTAFLFAFCVATPVVMYMLNKGGPRVVFMTASVLILVGNWIRY-AgtradNGIFgVVMFGQLL 177
                 5677888889999888888.99****************************************************66666.44666999*********** PP

       MFS_1  95 qGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg.Wravfyilaivsllafvlfllllpeepperkrkspkeeekgtg 192
                  Gl++ ++++a   +   wf+++ r++a++l+++++ lGa++g l+ ++ ++  g  + + + + ++s +a++    +l   +p+ ++ +++e      
  EEA20284.1 178 LGLAQPFALAAPTRYSDLWFSEKGRTSATALATLANPLGAAIGELVDSVWTTKPGdIPNMVLYISVISTVACI--PSFLIPARPPTPPCASAEV----S 270
                 **************************************************97777777776666666666644..3666666666666667777....7 PP

       MFS_1 193 paplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrlsdrlgr.rrrlllallllllaalg 290
                 ++p+++  k +++ + +w+++i + +   +f+++++l+  +  e +g+s   +ag++ ++l +vg+i++ +++ + dr+++   ++ +a+++ ++++++
  EEA20284.1 271 KTPFLESVKGIFRIREFWLMFIPFSVYVGFFNSVSALINQI-LEPYGFS-ETEAGIAGGVLIIVGLISSAIVSPINDRFKKyLLIIRIAVPIHAICYIA 367
                 9999999***********99999999999***********7.*******.9***************************999455566667777777777 PP

       MFS_1 291 lallavtssavllll....vlvliGfglgfvfpsllalasd 327
                 l++++ +   + +l+    v++l+G  ++   p +l ++++
  EEA20284.1 368 LYFAPSS---PYGLApsivVCALLGASAFALLPVALEFIVE 405
                 7777777...4444433347777888444445665555555 PP

>> MFS_2  MFS/sugar transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   4.4     0.019        85     257     313 ..     108     164 ..      79     223 .. 0.68
   2 !   35.6   1.2   8.6e-13   3.8e-09     138     337 ..     208     399 ..     196     407 .. 0.73
   3 ?   -1.6   0.1      0.17   7.5e+02     146     188 ..     426     466 ..     414     489 .. 0.59

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.019
       MFS_2 257 ngsaasvfllvvtisallgiplwqplakrlgkkntyllgalltivllvlvlllqpsn 313
                 +++ ++++++++  +  +++p++ ++  + g + +++ +++l +v+  + ++ + ++
  EEA20284.1 108 SEATINWLSTAFLFAFCVATPVVMYMLNKGGPRVVFMTASVLILVGNWIRYAGTRAD 164
                 666777777777777777777777777777777777777766666666666553322 PP

  == domain 2  score: 35.6 bits;  conditional E-value: 8.6e-13
       MFS_2 138 vrsflsvlggvlaailafllvlilgglkserkgylifaliialLmllgviivvlgtkervemrkkekteqkeklslleqlkevfrnraflillllflla 236
                    +++ lg +++ ++ ++           +     ++l i+++++++ i ++l+  +    +++ + ++ +k+++le +k +fr r f+++++ f++ 
  EEA20284.1 208 LATLANPLGAAIGELVDSVWTTK-------PGDIPNMVLYISVISTVACIPSFLIPARPP--TPPCASAEVSKTPFLESVKGIFRIREFWLMFIPFSVY 297
                 44444444444444444444333.......3347789999************99988665..579999999******************9888888776 PP

       MFS_2 237 alalgvlnglllYyltyvlg.ngsaasvfllvvtisallgiplwqplakrlgkkntyllgal.ltivllvlvlll..qpsnlllflvllviagfgvgva 331
                 +  ++   +l    l+   g ++++a +  +v++i +l+++++++p++ r+ k+ +++  a+ + ++ ++ ++++  +p+ l++ +v++++ g +  ++
  EEA20284.1 298 VGFFNSVSALINQILEP-YGfSETEAGIAGGVLIIVGLISSAIVSPINDRFKKYLLIIRIAVpIHAICYIALYFApsSPYGLAPSIVVCALLGAS--AF 393
                 66555555555555555.555*********************************66665555166677777777777777777777777777777..55 PP

       MFS_2 332 allpws 337
                 allp +
  EEA20284.1 394 ALLPVA 399
                 555544 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 0.17
       MFS_2 146 ggvlaailafllvlilgglkserkgylifaliialLmllgvii 188
                  g +++i++++l + +++  + + ++   +++ a+++++++i+
  EEA20284.1 426 LGGIFTIVQTALKAGPNA--NPPANMKGSLIFSAVVACVAAIF 466
                 344445555555444444..55556666666666665555554 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.5      0.28   1.3e+03     120     169 ..      77     125 ..      72     164 .. 0.55
   2 ?    1.0   0.9     0.034   1.5e+02     284     369 ..     134     223 ..      93     232 .. 0.76
   3 !    3.3   0.3    0.0068        30      54     135 ..     219     311 ..     192     312 .. 0.66
   4 !   24.6   2.0   2.3e-09     1e-05      22      87 ..     308     373 ..     289     381 .. 0.88

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.28
  MFS_1_like 120 lasfflaailvlldaatlkelgedrkdyGrqrlfGsvGyaifafitGili 169
                 l++++l  i++  d +t+  +++++ +y r+    ++ +  +af++ + +
  EEA20284.1  77 LFQLVLLNIVISWDWLTFSSISSTSAEYFRVSE-ATINWLSTAFLFAFCV 125
                 566666667777777777777777766655422.3333333333333333 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.034
  MFS_1_like 284 leklGhvklliial.layilrfllyaii..enaw..lvlpievLhgisfgllwaaaveyvskiapksleatgqgllsglyfglGralGsli 369
                 l+k G +++ ++a  l+ +  ++ ya +  +n    +v++ ++L g++     aa ++y+   ++++ ++   +l + +   lG a+G+l+
  EEA20284.1 134 LNKGGPRVVFMTASvLILVGNWIRYAGTraDNGIfgVVMFGQLLLGLAQPFALAAPTRYSDLWFSEKGRTSATALATLA-NPLGAAIGELV 223
                 556666666665540444557888888877555411456669*******99999******************9997655.89*****9987 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.0068
  MFS_1_like  54 wgvlaDrfgkrkk.....vvilslllsavlflsllfip...pskerqeesklevsvaqdvd......aektfwilfllvvlasfflaailvlldaa 135
                 +g l+D +  +k+     +v+  +++s+v+ +  ++ip   p   ++    +evs +  ++         +fw++f+  +++  f +++ +l++ +
  EEA20284.1 219 IGELVDSVWTTKPgdipnMVLYISVISTVACIPSFLIParpP---TPPCASAEVSKTPFLEsvkgifRIREFWLMFIPFSVYVGFFNSVSALINQI 311
                 566777777777666666666666666666666666996663...33333333333333333335557889***********99999999999876 PP

  == domain 4  score: 24.6 bits;  conditional E-value: 2.3e-09
  MFS_1_like  22 ltiylkskglkaseigiitlilpltsilsppiwgvlaDrfgkrkkvvilslllsavlflsllfipp 87 
                 +   l+  g++  e gi   +l ++ ++s+ i++++ Drf+k+  ++++++ + a+++++l+f p 
  EEA20284.1 308 INQILEPYGFSETEAGIAGGVLIIVGLISSAIVSPINDRFKKYLLIIRIAVPIHAICYIALYFAPS 373
                 56668889*******************************************************994 PP

>> DUF2798  Protein of unknown function (DUF2798)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.3   0.00011      0.49      27      48 ..     111     133 ..      96     136 .. 0.88
   2 ?    2.3   0.2     0.039   1.8e+02       9      47 ..     428     466 ..     424     476 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00011
     DUF2798  27 lsaWlk.awllAwpvAfpivllv 48 
                  ++Wl+ a+l+A++vA p+v+ +
  EEA20284.1 111 TINWLStAFLFAFCVATPVVMYM 133
                 6789999************9866 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.039
     DUF2798   9 limSgiitllnlGfsddflsaWlkawllAwpvAfpivll 47 
                 +i++ + t+l+ G++++  ++   + +++ +vA +++ +
  EEA20284.1 428 GIFTIVQTALKAGPNANPPANMKGSLIFSAVVACVAAIF 466
                 6899999********999999999999999998887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (508 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       616  (0.0343577); expected 358.6 (0.02)
Passed bias filter:                      346  (0.0192983); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.57u 0.24s 00:00:00.81 Elapsed: 00:00:00.41
# Mc/sec: 3698.81
//
Query:       EEA20285.1  [L=206]
Description: endoglucanase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.5e-53  179.4  11.3    1.4e-50  172.3  11.3    2.0  1  Glyco_hydro_12  Glycosyl hydrolase family 12


Domain annotation for each model (and alignments):
>> Glyco_hydro_12  Glycosyl hydrolase family 12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  172.3  11.3   7.7e-55   1.4e-50       2     214 .]      15     206 .]      14     206 .] 0.96

  Alignments for each domain:
  == domain 1  score: 172.3 bits;  conditional E-value: 7.7e-55
                     EEEEEE--TTEEEEEEEEEEEE-SSEEEEEEEEEEEEESSGB--EEEEE-BGGGTB--TT--.--EE.GGGEEEEEEEEEEEEE-TT--EEEEEE CS
  Glyco_hydro_12   2 pysvennlWgskegsgsvavkvdgekitssgasahtswkekgypevygGeksvksysnsgva.lpvk.vssvssiptevsfsiddtnvkanvayd 94 
                     py+v+nnlWg+   sgs++  v  + i+  g s+ t w++       g +++vksy+ns++  l +k  s+++ ipt++++++++tn++a+vayd
      EEA20285.1  15 PYTVSNNLWGQAGSSGSQCTDV--NSISNFGVSWTTAWNWA------GNNNQVKSYANSQLSgLTKKlASQLKGIPTSAQWGYSNTNINADVAYD 101
                     9******************666..59***************......88899*******975488888899************************ PP

                     EEEESSTT-S--TT-EEEEEEEE.EES---SSEEEEEEEETTEEEEEEE.EESSSEEEEEEESS--EEEEEEHHHHHHHHH-SS---GGGSEE-E CS
  Glyco_hydro_12  95 lflaaeknqvtsigdvElmiWlarygniqPiGekietavvgGetWelwlGaeaeqdvlsFvakspikgysfDvkdFldaltsargldaedlylis 189
                     lf++a+ n+v+++gd+ElmiWl +yg+ qP G++i+t                +q++ sFva+s+ +++ +D+ +F+++l +++g++a+++yli 
      EEA20285.1 102 LFTTADINHVSYSGDYELMIWLGKYGTAQPLGNQIGTR---------------SQKTDSFVASSQQTSWNGDILQFFHYLADHQGFPASSQYLID 181
                     ***********************************984...............68999************************************* PP

                     EEEE--B..--TT-EEEEEEEEEEE CS
  Glyco_hydro_12 190 lqiGtEpftgspetlkvenfsasve 214
                     lq+GtEpftg  +tl+v+ +sa v+
      EEA20285.1 182 LQFGTEPFTGDETTLTVNHWSAAVN 206
                     **********************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (206 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       494  (0.0275531); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.30s 00:00:00.72 Elapsed: 00:00:00.43
# Mc/sec: 1426.94
//
Query:       EEA20286.1  [L=761]
Description: involucrin repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.6e-43  146.2   1.7    5.6e-43  146.2   1.7    6.2  6  Uds1             Up-regulated During Septation
  ------ inclusion threshold ------
      0.014   15.9   9.8      0.014   15.9   9.8    7.2  6  APG6_N           Apg6 coiled-coil region
       0.03   14.6   1.1       0.03   14.6   1.1    6.6  8  WXG100           Proteins of 100 residues with WXG
        3.2    7.0  59.0       0.47    9.7  24.1    4.5  4  DUF4407          Domain of unknown function (DUF4407)


Domain annotation for each model (and alignments):
>> Uds1  Up-regulated During Septation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  146.2   1.7   1.3e-46   5.6e-43       2     130 .]      76     198 ..      75     198 .. 0.94
   2 ?   -1.0   0.0       0.4   1.8e+03      37      61 ..     251     272 ..     224     317 .. 0.58
   3 !    4.5   3.8    0.0085        38      23     117 ..     371     457 ..     367     458 .. 0.71
   4 ?    3.8  14.6     0.013        60       7     116 ..     423     542 ..     417     544 .. 0.78
   5 ?   -1.9   7.1      0.78   3.5e+03      51     116 ..     504     573 ..     503     577 .. 0.55
   6 ?   -5.9  10.4         4   1.8e+04      24     112 ..     601     684 ..     594     754 .. 0.58

  Alignments for each domain:
  == domain 1  score: 146.2 bits;  conditional E-value: 1.3e-46
        Uds1   2 hlLvetAlvdsqefeiLsleeVeelkkelkaLeerlealrkkLaletklrdaarsLsrlyssskksakssaarsnskssreslakaeeelaeserkvde 100
                 hlL+etA++ds+ +eiL +eeVe+lk+e++aL++r+e +++kLaletklrdaa+sL+rl+ s k++       +n+ ++  +++ +++e+a+s+rk++e
  EEA20286.1  76 HLLTETAIGDSTGYEILPFEEVEDLKREYAALSNRVEGTKRKLALETKLRDAAQSLRRLS-SLKSN-----GYTNGDTNGIAHHPEDAEYANSSRKCEE 168
                 9**********************************************************9.54444.....45677777779***************** PP

        Uds1 101 laselekleeraaevrrrLLeHtAavLqlt 130
                 la+el+ le+ra++v++rLLeHtA++Lqlt
  EEA20286.1 169 LAQELWALERRAQDVHKRLLEHTAGILQLT 198
                 ****************************86 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.4
        Uds1  37 lealrkkLaletklrdaarsLsrly 61 
                 +++lr++   e+kl +   +L+ l 
  EEA20286.1 251 VNTLRNT---EQKLEELNGRLRDLL 272
                 3334444...444444444444444 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.0085
        Uds1  23 VeelkkelkaLeerlealrkkLaletklrdaarsLsrlyssskksakssaarsnskssreslakaeeelaeserkvdelaselekleeraaevrr 117
                 ++ lk  ++ L++r+  l+ +   ++ l +  ++ ++l+s+s ++     ++ + ++  ++l ++++e++ ser  +++ +el  + e++ +vr+
  EEA20286.1 371 IDYLKSGMSDLQNRVAGLQDQ---KSILTTQIQQQRELNSKSDAE-----KDAHVADLAQQLVETKKEYELSERELEAVRDELALVMEQLDTVRQ 457
                 567788888899999998887...444444444444555333333.....333445556789999999999999999999999999999999988 PP

  == domain 4  score: 3.8 bits;  conditional E-value: 0.013
        Uds1   7 tAlvdsqefeiLsleeVeelkkelkaLeerlealrkkLaletklrdaarsLsrlyssskksak...........ssaarsnskssreslakaeeelaes 94 
                 + +   +e+e Ls  e+e+++ el+ + e+l+++r++ +++ + r+  ++ +  + + ++s+            ++ +++ ++++ e+l++++e+++ +
  EEA20286.1 423 QLVETKKEYE-LSERELEAVRDELALVMEQLDTVRQQENIQDQQREREKAVAFENEKGARSKAeaevqrlrdkvNYLEGEYAREQAEALEREMEARSRA 520
                 4444555666.7889999999999999999999998777766666666665555555555544789*******9999999999999************* PP

        Uds1  95 erkvdelaselekleeraaevr 116
                 e+ v+ l+ el +l  + a+ +
  EEA20286.1 521 ETEVERLQGELTQLGGESARAQ 542
                 ***********99977766655 PP

  == domain 5  score: -1.9 bits;  conditional E-value: 0.78
        Uds1  51 rdaarsLsrlyssskksak.......ssaarsnskssreslakaeeelaeserkvdelaselekleeraaevr 116
                 r+ a++L+r + + ++ ++       +    ++   +++  ++ae+e + +++   el+se+ +++++++ v+
  EEA20286.1 504 REQAEALEREMEARSRAETeverlqgE---LTQLGGESARAQTAETEAQRLQAELTELESEFARAQTELTVVK 573
                 566666666663333332256553320...2223333445667777777777777777777777777766665 PP

  == domain 6  score: -5.9 bits;  conditional E-value: 4
        Uds1  24 eelkkelkaLeerlealrkkLaletklrdaarsLsrlyssskksakssaarsnskssreslakaeeelaeserkvdelaselekleera 112
                 e+l  +  +L e l alr++   +    ++  +L+++  + +k+   + + +  +   +++ + e+e+++ e  +d+l + +e+le ++
  EEA20286.1 601 EDLNTKNISLAEELAALRAE---KVNNGAGQGELQKRVETLQKE--LEETIEDYEAMTKASIEFEKEREQYEGMIDNLRDRIEQLEAQL 684
                 55555555555555555555...222233334555555333333..2222222223334455555566666666666666666665544 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   6.7      0.58   2.6e+03      33      89 ..     109     192 ..      34     208 .. 0.67
   2 ?   -3.0   0.1       2.1   9.5e+03      72      80 ..     256     264 ..     247     277 .. 0.42
   3 ?   -2.8  21.9       1.9   8.7e+03      33     103 ..     403     471 ..     365     499 .. 0.69
   4 ?   -4.6  27.5         4   1.8e+04      15     125 ..     458     568 ..     456     591 .. 0.51
   5 ?   15.9   9.8   3.2e-06     0.014      49     127 ..     593     671 ..     581     677 .. 0.90
   6 ?    4.5   9.8     0.011        49      14      91 ..     652     752 ..     650     754 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.58
      APG6_N  33 kklkkekkeeek...........................qdeeleeleeeleklekeeeelleeLkelekereeleaelaalee 89 
                 ++++ +k++                              +   +   + e+++ +++ eel +eL +le+  +++ + l + ++
  EEA20286.1 109 NRVEGTKRKLALetklrdaaqslrrlsslksngytngdtNGIAHHPEDAEYANSSRKCEELAQELWALERRAQDVHKRLLEHTA 192
                 444444333322222333333333333333333333333222222334456777777777777777777777777777666555 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 2.1
      APG6_N  72 elekereel 80 
                 ++e++ eel
  EEA20286.1 256 NTEQKLEEL 264
                 222222222 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 1.9
      APG6_N  33 kklkkekkeeekqdeeleeleeeleklekeeeelleeLkelekereeleaelaaleeelealeeeeerfwr 103
                 ++l+++++ e  +d  +++l ++l +++ke e  ++eL+++ +e + + ++l + +++++  +++ er+  
  EEA20286.1 403 RELNSKSDAE--KDAHVADLAQQLVETKKEYELSERELEAVRDELALVMEQLDTVRQQENIQDQQREREKA 471
                 3344443333..58899999999999*************************99999999999988877654 PP

  == domain 4  score: -4.6 bits;  conditional E-value: 4
      APG6_N  15 dkqleqaekerdaYeeflkklkkekkeeek...............qdeeleeleeeleklekeeeelleeLkele.kereeleaelaaleeelealeee 97 
                 ++ ++++++er++  +f+++  +++k e +                                   + ++e  e e ++r++ e e++ l+ el +l  e
  EEA20286.1 458 QENIQDQQREREKAVAFENEKGARSKAEAEvqrlrdkvnylegeyA-------------------REQAEALEREmEARSRAETEVERLQGELTQLGGE 537
                 6788999999999999999999998776635555555555444442...................3333333322122344444444444444444444 PP

      APG6_N  98 eerfwreyne...lqlelleleeeldsleaq 125
                  +r  +   e   lq el+ele e +  +++
  EEA20286.1 538 SARAQTAETEaqrLQAELTELESEFARAQTE 568
                 4433332222111222222222222222222 PP

  == domain 5  score: 15.9 bits;  conditional E-value: 3.2e-06
      APG6_N  49 leeleeeleklekeeeelleeLkelekereeleaelaaleeelealeeeeerfwreynelqlelleleeeldsleaqye 127
                   +l +e+e+l+ +  +l eeL++l +e+ +  a   +l++  e l++e e+ +++y +     +e+e+e+++ e  ++
  EEA20286.1 593 NPALYKEIEDLNTKNISLAEELAALRAEKVNNGAGQGELQKRVETLQKELEETIEDYEAMTKASIEFEKEREQYEGMID 671
                 567889******************************************************************9987766 PP

  == domain 6  score: 4.5 bits;  conditional E-value: 0.011
      APG6_N  14 ldkqleqaekerdaYeeflkklkkekkeeek......................qdeeleeleeeleklekeee.elleeLkelekereeleaelaalee 89 
                 ++k   + eker++Ye   ++l+++ ++ e+                      + +++  l++e++k+ ++ + e ++ L++ ++er++lea +++l+ 
  EEA20286.1 652 MTKASIEFEKEREQYEGMIDNLRDRIEQLEAqlsderitwmgvsqtamrdgamETTSTMVLKNEFKKMMRDTRtENMKLLRAEQEERKKLEALVRSLKM 750
                 666777889****************9998879****************999998888889999999966655505555555556678899999999887 PP

      APG6_N  90 el 91 
                 e 
  EEA20286.1 751 EQ 752
                 75 PP

>> WXG100  Proteins of 100 residues with WXG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       1.1   4.8e+03       9      28 ..      97     116 ..      94     134 .. 0.52
   2 ?   -2.6   0.0       1.5   6.8e+03      23      37 ..     247     261 ..     234     270 .. 0.61
   3 ?   -3.4   0.1       2.7   1.2e+04      21      37 ..     328     344 ..     326     348 .. 0.53
   4 ?   -2.4   0.2       1.3   5.7e+03      16      33 ..     374     391 ..     365     404 .. 0.56
   5 ?   -2.0   0.2         1   4.5e+03       9      23 ..     424     438 ..     412     458 .. 0.49
   6 ?    5.1   0.8     0.006        27      19      68 ..     480     532 ..     471     544 .. 0.74
   7 ?    3.9   1.8     0.014        64       7      66 ..     542     606 ..     538     620 .. 0.60
   8 ?   14.6   1.1   6.6e-06      0.03       5      60 ..     648     710 ..     646     735 .. 0.86

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 1.1
                 HHHHHHHHHHHHHHHHHHHH CS
      WXG100   9 lrqaaarfqkqaeeledelq 28 
                 +++  +++++ ++++e+  +
  EEA20286.1  97 VEDLKREYAALSNRVEGTKR 116
                 44444444444444444333 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.5
                 HHHHHHHHHHHHHHC CS
      WXG100  23 ledelqrlkaevdal 37 
                 l++ +++l+++ ++l
  EEA20286.1 247 LTADVNTLRNTEQKL 261
                 555555555555544 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 2.7
                 HHHHHHHHHHHHHHHHC CS
      WXG100  21 eeledelqrlkaevdal 37 
                 +e+ +el+++++ +++l
  EEA20286.1 328 SEMGSELSAINSRLQNL 344
                 45555555666655555 PP

  == domain 4  score: -2.4 bits;  conditional E-value: 1.3
                 HHHHHHHHHHHHHHHHHH CS
      WXG100  16 fqkqaeeledelqrlkae 33 
                 +++  ++l+++++ l+ +
  EEA20286.1 374 LKSGMSDLQNRVAGLQDQ 391
                 444445555555555544 PP

  == domain 5  score: -2.0 bits;  conditional E-value: 1
                 HHHHHHHHHHHHHHH CS
      WXG100   9 lrqaaarfqkqaeel 23 
                 l ++ +++  ++ el
  EEA20286.1 424 LVETKKEYELSEREL 438
                 223333333333333 PP

  == domain 6  score: 5.1 bits;  conditional E-value: 0.006
                 HHHHHHHHHHHHHHHHHHCGCGCTHHHCHHHHHHHH.HHH..HHHHHHHHHHH CS
      WXG100  19 qaeeledelqrlkaevdalqsgWsGaaadafqaefe.ewk..qaaqklvdaLe 68 
                 ++++ e+e+qrl+ +v++l++ +  + a+a + e+e + +   ++++l+ +L+
  EEA20286.1 480 ARSKAEAEVQRLRDKVNYLEGEYAREQAEALEREMEaRSRaeTEVERLQGELT 532
                 5678899*****************99999999999943330023344444444 PP

  == domain 7  score: 3.9 bits;  conditional E-value: 0.014
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCGCGCTHH....HCHHHHHHHH.HHHHHHHHHHHH CS
      WXG100   7 eelrqaaarfqkqaeeledelqrlkaevdalqsgWsGa....aadafqaefe.ewkqaaqklvda 66 
                 +  ++ a+r+q++ +ele+e +r + e+  +++   Ga    a  a +a+ +  +++++++l+++
  EEA20286.1 542 QTAETEAQRLQAELTELESEFARAQTELTVVKAELDGAygtrAERAAEAAANpALYKEIEDLNTK 606
                 56677888888888888888888888776665554444111155555555555555555555555 PP

  == domain 8  score: 14.6 bits;  conditional E-value: 6.6e-06
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCGC.......GCTHHHCHHHHHHHHHHHHHH CS
      WXG100   5 dpeelrqaaarfqkqaeeledelqrlkaevdalqs.......gWsGaaadafqaefeewkqaa 60 
                 d+e++++a+ +f k++e+ e+++++l+  +++l++       +W G +++a ++  +e + ++
  EEA20286.1 648 DYEAMTKASIEFEKEREQYEGMIDNLRDRIEQLEAqlsderiTWMGVSQTAMRDGAMETTSTM 710
                 89*******************************6659999999********999888877766 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   1.7     0.014        64     144     239 ..      99     214 ..      91     220 .. 0.47
   2 ?    2.8   9.8     0.014        61     131     222 ..     374     471 ..     327     477 .. 0.56
   3 ?    9.7  24.1   0.00011      0.47     107     235 ..     460     592 ..     456     621 .. 0.81
   4 ?    5.5   6.4     0.002         9     108     215 ..     631     744 ..     627     753 .. 0.67

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.014
     DUF4407 144 alqaeidaaearldalraeaqkeldgtk....................gtgttgvaGkgpaakekkaqldaaqaelaelkakld.atarlaalraelae 221
                 +l++e++a+++r++ ++++++ e++                       ++g+   + + ++a +  ++ +++ +el +l+++ +   +rl ++ a + +
  EEA20286.1  99 DLKREYAALSNRVEGTKRKLALETKLRDaaqslrrlsslksngytngdTNGIAHHPEDAEYANS-SRKCEELAQELWALERRAQdVHKRLLEHTAGILQ 196
                 4444444444444444444444444333444444444444333333336666655555444433.4444444444444444422355556666666666 PP

     DUF4407 222 leaerakeraasqaaaaa 239
                 l+ +  k++a+  ++++a
  EEA20286.1 197 LTHRGLKKNANRGSMNNA 214
                 555555555555555555 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.014
     DUF4407 131 ltaelaeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaakekkaqldaaqaelaelkakld..........atarlaalrael 219
                 l++ +++l++++a lq + + + ++++++r+   k  d +k +    va   +   e k++++  ++el++++++l           ++++++++++e+
  EEA20286.1 374 LKSGMSDLQNRVAGLQDQKSILTTQIQQQRELNSKS-DAEKDAH---VADLAQQLVETKKEYELSERELEAVRDELAlvmeqldtvrQQENIQDQQRER 468
                 556667777777777777777777776655544433.3333222...3333333333444444444444444444444332212555555555555555 PP

     DUF4407 220 ael 222
                 +++
  EEA20286.1 469 EKA 471
                 544 PP

  == domain 3  score: 9.7 bits;  conditional E-value: 0.00011
     DUF4407 107 eIdaelaeeqqeeakelkeqlaaaltaelaeleaqiaalqaeidaaearldalraeaqkeldgtk...gtgttgvaGkgpaakekkaqldaaqaelael 202
                  I+ + +e+ ++ a e+++  +++++ae+++l+++++ l++e++  +a++ + + ea++ ++ +    + + t+  G+ ++a++++++++++qael+el
  EEA20286.1 460 NIQDQQREREKAVAFENEKGARSKAEAEVQRLRDKVNYLEGEYAREQAEALEREMEARSRAETEVerlQGELTQLGGESARAQTAETEAQRLQAELTEL 558
                 466666666666666677777777*********************************999998779996677889************************ PP

     DUF4407 203 kakld.atarlaalraelaeleaerakeraasqa 235
                 +++   a+++l+  +ael+++   ra+++a+ +a
  EEA20286.1 559 ESEFArAQTELTVVKAELDGAYGTRAERAAEAAA 592
                 ***8887888888888888877777776665554 PP

  == domain 4  score: 5.5 bits;  conditional E-value: 0.002
     DUF4407 108 Idaelaeeqqeeakelkeqlaaa..ltaelaeleaqiaalqaeidaaearldalraeaqkeldgtk.gtgttgvaGkgpaake.......kkaqldaaq 196
                 +++++++ q+e ++++    ++   +t+   e e+++++ ++ id++++r+++l+a++ +e       ++t  + G  + + +       kk + d+++
  EEA20286.1 631 LQKRVETLQKELEETI----EDYeaMTKASIEFEKEREQYEGMIDNLRDRIEQLEAQLSDERITWMgVSQTAMRDGAMETTSTmvlknefKKMMRDTRT 725
                 4444444444444444....3334488888899999999999***************999988655544444444554444448888899899999999 PP

     DUF4407 197 aelaelkakldatarlaal 215
                 ++++ l+a+ +++++l+al
  EEA20286.1 726 ENMKLLRAEQEERKKLEAL 744
                 9999988884444444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (761 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2272  (0.126722); expected 358.6 (0.02)
Passed bias filter:                      556  (0.0310112); expected 358.6 (0.02)
Passed Vit filter:                        91  (0.00507558); expected 17.9 (0.001)
Passed Fwd filter:                        59  (0.00329076); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.57u 0.34s 00:00:01.91 Elapsed: 00:00:00.56
# Mc/sec: 4090.94
//
Query:       EEA20287.1  [L=856]
Description: F-box and WD domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    7.9e-31  105.6   8.1    0.00013   22.7   0.1    8.3  9  WD40         WD domain, G-beta repeat
      4e-12   45.8   0.3    1.1e-11   44.4   0.3    1.8  1  F-box-like   F-box-like
    1.5e-08   34.3   0.0    3.8e-08   33.0   0.0    1.6  1  F-box        F-box domain
     0.0004   20.6   0.6        1.2    9.4   0.0    3.6  3  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
      0.005   16.2   0.1        1.2    8.4   0.0    2.4  2  WD40_like    WD40-like domain
  ------ inclusion threshold ------
      0.096   13.3   0.0       0.23   12.1   0.0    1.5  1  MgtE_N       MgtE intracellular N domain
       0.11   11.4   0.0       0.52    9.2   0.0    1.9  2  PALB2_WD40   Partner and localizer of BRCA2 WD40 domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.1   2.7e-07   0.00069       9      38 .]     309     337 ..     300     337 .. 0.86
   2 !   20.6   0.0   2.3e-07   0.00058       3      38 .]     344     382 ..     342     382 .. 0.86
   3 !   16.6   0.0   4.3e-06     0.011       2      38 .]     387     423 ..     386     423 .. 0.83
   4 !   14.8   0.0   1.5e-05      0.04       3      38 .]     477     511 ..     475     511 .. 0.81
   5 !   22.7   0.1     5e-08   0.00013       1      38 []     515     551 ..     515     551 .. 0.92
   6 ?    0.8   0.0       0.4     1e+03       3      16 ..     557     571 ..     555     581 .. 0.76
   7 ?    5.3   0.1     0.015        40      23      37 ..     646     662 ..     635     663 .. 0.86
   8 ?   -2.7   0.0       5.2   1.3e+04      20      29 ..     666     674 ..     665     675 .. 0.81
   9 ?   -1.2   0.0       1.8   4.6e+03      14      38 .]     816     838 ..     803     838 .. 0.70

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 2.7e-07
                 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +H ++v+++  +  g+w++sGs+D t+r+Wd
  EEA20287.1 309 AHqQCVYAI--QFVGKWMVSGSRDTTIRVWD 337
                 787778888..7789***************9 PP

  == domain 2  score: 20.6 bits;  conditional E-value: 2.3e-07
                 EEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGH.ssvtsla..fspdgawlasGsdDgtvriWd 38 
                 cl  l+GH +sv +l+   sp+ + ++sG+ D++v iW+
  EEA20287.1 344 CLPPLRGHqTSVLCLQfdPSPEEDVIMSGGSDNNVIIWK 382
                 77789***999*****77777777799**88*******6 PP

  == domain 3  score: 16.6 bits;  conditional E-value: 4.3e-06
                 EEEEEEE.SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtlt.GH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 q+l +lt +H +sv  l    d+++l+++s+D+ +++W+
  EEA20287.1 387 QKLLELTnAHqDSVLNL--KFDKRYLVTCSKDKLIKVWN 423
                 56667766997779999..55999**************8 PP

  == domain 4  score: 14.8 bits;  conditional E-value: 1.5e-05
                 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +l tl+GH   v++++ ++d    ++++ D+ +++W+
  EEA20287.1 477 LLMTLEGHdAAVNAIQINDDEIV-SAAG-DRLIKVWS 511
                 7899****666****77777777.4568.*******5 PP

  == domain 5  score: 22.7 bits;  conditional E-value: 5e-08
                 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 g+cl+t+ GH +++ ++  + d++ ++sGs D t+ri+d
  EEA20287.1 515 GSCLKTILGHkKGIACV--QFDNRRIISGSNDDTIRIYD 551
                 68********999****..77888899***********8 PP

  == domain 6  score: 0.8 bits;  conditional E-value: 0.4
                 EEEEEESSSS.EEEE CS
        WD40   3 clrtltGHss.vtsl 16 
                  + tl+GHs+ v+++
  EEA20287.1 557 EVATLEGHSNlVRAV 571
                 6789****5569998 PP

  == domain 7  score: 5.3 bits;  conditional E-value: 0.015
                 SE..EEEEETTSEEEEE CS
        WD40  23 aw..lasGsdDgtvriW 37 
                 +w  ++sGs+D tv iW
  EEA20287.1 646 RWarIVSGSYDETVIIW 662
                 565579*********** PP

  == domain 8  score: -2.7 bits;  conditional E-value: 5.2
                 TTSSEEEEEE CS
        WD40  20 pdgawlasGs 29 
                 +dg+wl+ G+
  EEA20287.1 666 RDGRWLV-GH 674
                 79***98.87 PP

  == domain 9  score: -1.2 bits;  conditional E-value: 1.8
                 EEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  14 tslafspdgawlasGsdDgtvriWd 38 
                 + l  + d + ++++s D  +  Wd
  EEA20287.1 816 YKL--QFDARKIICASQDSRIVGWD 838
                 555..445566888999*9999887 PP

>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.4   0.3   4.4e-15   1.1e-11       2      48 .]      99     144 ..      98     144 .. 0.95

  Alignments for each domain:
  == domain 1  score: 44.4 bits;  conditional E-value: 4.4e-15
  F-box-like   2 srLPdEiLlqIFsyLppsdLlrlalVCrrWrrvaldtplLWrrlvlr 48 
                 +rLP+Ei  +IFsyL+p +L  ++l +r Wr+ ++d+ +LW+ +++r
  EEA20287.1  99 LRLPPEITAEIFSYLDPATLHTASLASRAWRNRIADP-RLWKDMYIR 144
                 69********************************998.*****9986 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.0   0.0   1.5e-11   3.8e-08       2      44 ..      97     139 ..      96     142 .. 0.95

  Alignments for each domain:
  == domain 1  score: 33.0 bits;  conditional E-value: 1.5e-11
                 HHHHS-HHHHHHHHHTS-HHHHHHHCTT-HHHHHHHTTHHHHH CS
       F-box   2 tlsrLPsevlrhILerLplsdllalrrVSkgwrilidsdrlwc 44 
                 + +rLP+e+  +I+++L++ +l  +++ S+ wr+ i ++rlw+
  EEA20287.1  97 PVLRLPPEITAEIFSYLDPATLHTASLASRAWRNRIADPRLWK 139
                 679***************************************7 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.4   0.0   0.00049       1.2      27      90 ..     333     406 ..     306     408 .. 0.82
   2 ?    4.1   0.1     0.022        57      36      90 ..     483     534 ..     468     536 .. 0.77
   3 ?    3.9   0.0     0.025        65      49      81 ..     534     566 ..     532     574 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00049
  ANAPC4_WD40  27 qrvwtl........eedkedsevrsLaWk..pdgklLavaysdgevrlldaesgkvvhslsvksekavtclgWg 90 
                   rvw+l        +  +++ +v +L++   p++ +++ + sd++v + + ++g+ + +l+ +++++v  l++ 
   EEA20287.1 333 IRVWDLsrmrlclpPLRGHQTSVLCLQFDpsPEEDVIMSGGSDNNVIIWKFSTGQKLLELTNAHQDSVLNLKFD 406
                  46666666666666778899999999996226799*******************99888888777789988875 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.022
  ANAPC4_WD40  36 kedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgWg 90 
                  ++d  v++++ +  +  ++ a  d  +++ ++++g +++++  +++  ++c+++ 
   EEA20287.1 483 GHDAAVNAIQIN--DDEIVSAAGDRLIKVWSIHNGSCLKTILGHKK-GIACVQFD 534
                  566666666554..4457889999****************977777.6***9986 PP

  == domain 3  score: 3.9 bits;  conditional E-value: 0.025
  ANAPC4_WD40  49 dgklLavaysdgevrlldaesgkvvhslsvkse 81 
                  d++ +  + +d ++r++d  sg  v +l+ +s+
   EEA20287.1 534 DNRRIISGSNDDTIRIYDHASGAEVATLEGHSN 566
                  7788999******************99988877 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.4   0.0   0.00047       1.2       7      65 ..     361     419 ..     358     433 .. 0.81
   2 !    5.2   0.0    0.0043        11       9      42 ..     532     565 ..     479     572 .. 0.77

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00047
   WD40_like   7 diskkgslilyGgkddkctvlklesles.vsivesfedSvifvklldddlilvvtlDGti 65 
                 d s++ ++i+ Gg d+++ + k+ ++++   + +  +dSv+  k+ d+  ++ ++ D  i
  EEA20287.1 361 DPSPEEDVIMSGGSDNNVIIWKFSTGQKlLELTNAHQDSVLNLKF-DKRYLVTCSKDKLI 419
                 66888999****************987615678889*******98.56666678888777 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0043
   WD40_like   9 skkgslilyGgkddkctvlkleslesvsivesfe 42 
                 ++++  i+ G++dd++++++  s+ +v  +e+ +
  EEA20287.1 532 QFDNRRIISGSNDDTIRIYDHASGAEVATLEGHS 565
                 4566778888888888888888888877777655 PP

>> MgtE_N  MgtE intracellular N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   8.8e-05      0.23      39      89 ..      67     117 ..      58     122 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 8.8e-05
                 CCCCCHHHHCS-HHHHHHHHCCS-HHHHHHHHCCCHHHHHHHHHHCS-HHH CS
      MgtE_N  39 edlqeeliealsdeelaelleeldsDdaadlleelpeekveellsaldeee 89 
                  +l+++++++l+ + +a++++ l++    d + +lp+e+++e++s ld+++
  EEA20287.1  67 AELAQSILTSLPTSLIASVVDRLTPRLHMDPVLRLPPEITAEIFSYLDPAT 117
                 568899999999999999999999999999999999999999999999976 PP

>> PALB2_WD40  Partner and localizer of BRCA2 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.0    0.0002      0.52     189     227 ..     365     401 ..     348     413 .. 0.82
   2 ?   -1.0   0.0      0.26   6.6e+02     182     216 ..     487     521 ..     471     532 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0002
  PALB2_WD40 189 ekdallgttvlnniviWnlktGqllkkieigesyqasvc 227
                 e+d +++   +nn++iW   tGq l  +e+ ++ q+sv 
  EEA20287.1 365 EEDVIMSGGSDNNVIIWKFSTGQKL--LELTNAHQDSVL 401
                 68999999***************77..567788888876 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.26
  PALB2_WD40 182 afaeveGekdallgttvlnniviWnlktGqllkki 216
                 a   ++   d +++++ +  i +W ++ G  lk+i
  EEA20287.1 487 AVNAIQINDDEIVSAAGDRLIKVWSIHNGSCLKTI 521
                 56667788899999999999*********999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (856 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       807  (0.0450109); expected 358.6 (0.02)
Passed bias filter:                      475  (0.0264934); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.70u 0.26s 00:00:00.96 Elapsed: 00:00:00.43
# Mc/sec: 5973.24
//
Query:       EEA20288.1  [L=932]
Description: Rho guanyl nucleotide exchange factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      8e-41  139.2   0.0    2.1e-40  137.8   0.0    1.8  2  PH_10     Pleckstrin homology domain
    1.3e-35  121.5   0.0    2.4e-35  120.6   0.0    1.5  1  CDC24     CDC24 Calponin
    2.6e-22   79.9   1.4    4.1e-22   79.3   1.4    1.3  1  RhoGEF    RhoGEF domain
    1.2e-08   34.8   0.1    2.3e-08   33.8   0.1    1.5  1  PB1       PB1 domain
  ------ inclusion threshold ------
      0.062   13.8   0.0       0.13   12.8   0.0    1.5  1  PH        PH domain


Domain annotation for each model (and alignments):
>> PH_10  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   0.0       4.9   1.7e+04      63      85 ..     334     356 ..     328     365 .. 0.67
   2 !  137.8   0.0   5.8e-44   2.1e-40       2     123 .]     387     509 ..     386     509 .. 0.93

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 4.9
       PH_10  63 kkktklqLKGrilisnvtevtss 85 
                 ++++ lq +  i i+ +++v +s
  EEA20288.1 334 TDDEALQSRITIAINMIQSVLDS 356
                 45556666667777788888754 PP

  == domain 2  score: 137.8 bits;  conditional E-value: 5.8e-44
       PH_10   2 kfGeLllhdtltVkkd...sdsereyevyLFekillcvkevkeekkkksksssllkkkssssskkkktklqLKGrilisnvtevtssskpgsyslqisw 97 
                  fGeLl+++t+tV k+   +dserey++yLF++illc+k+v+++ k+ksk   +++k s++   k k++lqLKGri+++nvt+v+  +kpgsy +qi+w
  EEA20288.1 387 GFGELLRFGTFTVLKGegnKDSEREYHIYLFQRILLCCKDVNPN-KQKSKLIGSKDKPSAN--FKGKPRLQLKGRIYMANVTDVVLLQKPGSYRIQIFW 482
                 6**************9999**********************999.7777788877776654..69********************************** PP

       PH_10  98 kgdke.lesftlrfkneeqlkkWesal 123
                 kgd++ +++f++r+ ne+ +kkW +++
  EEA20288.1 483 KGDPGvVDNFIIRYVNEDIMKKWYQDI 509
                 ***********************9986 PP

>> CDC24  CDC24 Calponin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  120.6   0.0   6.7e-39   2.4e-35       1      89 []      62     150 ..      62     150 .. 0.99

  Alignments for each domain:
  == domain 1  score: 120.6 bits;  conditional E-value: 6.7e-39
       CDC24   1 dPvtqlwkllrqGspLlalfNalkpeeklevdevksddlkvcKksvydFllackkeLgfedeelftisdlfsedttdlvkvlkvvnkvl 89 
                 dPv++lw++lr G+pL+++fNa +p+e+levd++k+ ++k++K+++++Fl+ac++++gf+++++f+i+dl++e+tt+++kv+k+vn+vl
  EEA20288.1  62 DPVNSLWTCLRAGYPLITIFNASQPDEMLEVDPEKVPEAKRPKAATFKFLQACLQDMGFPQQDCFLITDLYGENTTGFIKVIKMVNRVL 150
                 9**************************************************************************************97 PP

>> RhoGEF  RhoGEF domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.3   1.4   1.2e-25   4.1e-22       1     182 []     185     358 ..     185     358 .. 0.84

  Alignments for each domain:
  == domain 1  score: 79.3 bits;  conditional E-value: 1.2e-25
                 HHHHHHHHHHHHHHHHHHHHHHTHCCCHHCTCCHHHHHHHHCTTHHHHHHHHHHHHHHHHHHHH.HHHTTSS-S-SHHHHHHHHSTHHHHHHHHHCHHH CS
      RhoGEF   1 vikElleTErsYvrdLkvlvevylkplselevlseeeikiiFsnieeilelhrsflleeLeerlkeseeqkeaqsigdvflkfadkfkkYseYcsnypn 99 
                 ++kEll TEr+Yv++L+ l+    k l+e   ++ +  ++iF+n++++l+   + +l ++e+ +      +e q+ g +f ++ + ++ Y+ ++sn+ +
  EEA20288.1 185 ILKELLVTERDYVHHLQNLQ-ALKKELEETGAITGDLSHQIFMNLNDLLDSA-QRFLIRMEQHY---ALPEERQDWGALFIENEEFLRRYEPFISNQLQ 278
                 689****************6.66667888889********************.66666688888...566678899*********9************* PP

                 HHHHHHHHHHHHHHHHHHHHHHHTSGGGTT--HHHHTTHHHHHHHHHHHHHHHHHHTS-TTSHHHHHHHHHHHHHHHHHHHHH CS
      RhoGEF 100 alkllkelskknkkfkafleeaeerpecskldLeslLikPvqRlprYpLLLkellkntpeshpdyealkkaleaikevaseiN 182
                 + +++ ++ +k+k       ++++   + + +L+s+ +kP+ Rl +YpL+L el k+t+++   ++ +  a+++i++v+++ N
  EEA20288.1 279 CDEVCLREWDKIKVA-PRSPDLQQM-VAMQATLNSFFLKPFNRLAKYPLILGELRKQTDDE-ALQSRITIAINMIQSVLDSAN 358
                 *****9955444444.333333333.33799***************************665.44579***********99987 PP

>> PB1  PB1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.8   0.1   6.5e-12   2.3e-08       3      82 ..     836     928 ..     834     930 .. 0.86

  Alignments for each domain:
  == domain 1  score: 33.8 bits;  conditional E-value: 6.5e-12
                 EEEEEETTEEEEEEEEGSSS-HHHHHHHHHHHHTST......CCSEEEEEEETTSSEEEESSHHHHHHHHHHHHHT........SSCCEEEEEE CS
         PB1   3 dlKlrygggirrelsvssnisfeeLrakvekrfkls......dedvklkYpdedgdlVtitsDeDLeealeearsl........ksktlrlhvq 82 
                 + K+ +++  +  l ++sni f++L ++v  ++++       + +v+l Y+dedgd++ti sDe ++ a+ e r          + ++++l++q
  EEA20288.1 836 KAKVNFDDNYVT-LVIASNILFRSLTDRVDAKLARFtnrsigNRSVRLRYKDEDGDFITIDSDEAVQLAFMEWRDQhqdslaqgQVGEIQLFCQ 928
                 568899999999.*******************99999999******************************998876666666655556666665 PP

>> PH  PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   3.7e-05      0.13      10     102 ..     401     511 ..     384     513 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 3.7e-05
                 ETSSSSCSEEEEEEEEETTEEEEESST....................TCTTESSEEEEEESTTEEEEEEECTTSSSSTSEEEEEESTSSS.TEEEEEEE CS
          PH  10 kgsgkkkswkkrwfvLkdsellyyknd....................ksekdkepkgsislsncevvevvatedpkrkfcfelriverng.srtyllqa 87 
                 kg+g+k s ++++++L++  ll +k+                     k++++ ++kg i + n+++v      +++  + +++  + + g  ++++++ 
  EEA20288.1 401 KGEGNKDSEREYHIYLFQRILLCCKDVnpnkqkskligskdkpsanfKGKPRLQLKGRIYMANVTDVVL---LQKPGSYRIQIFWKGDPGvVDNFIIRY 496
                 6667777999999****9999999999****************************************74...38888888888444334456******* PP

                 SSHHHHHHHHHHHHH CS
          PH  88 sseeerkeWikaiqs 102
                  +e+ +k+W+++i +
  EEA20288.1 497 VNEDIMKKWYQDIDR 511
                 ***********9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (932 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       546  (0.0304535); expected 358.6 (0.02)
Passed bias filter:                      439  (0.0244855); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.72u 0.28s 00:00:01.00 Elapsed: 00:00:00.48
# Mc/sec: 5868.20
//
Query:       EEA20289.1  [L=483]
Description: aminotransferase, classes I and II, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.4e-34  119.1   0.0    2.8e-34  118.9   0.0    1.0  1  Aminotran_1_2  Aminotransferase class I and II


Domain annotation for each model (and alignments):
>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.9   0.0   1.6e-38   2.8e-34      31     353 ..     103     448 ..      78     458 .. 0.85

  Alignments for each domain:
  == domain 1  score: 118.9 bits;  conditional E-value: 1.6e-38
                    HHHHTSTTST-BTTHHHHHHHHHHHHHC....TCTTCHTTGGEGEEEESHHHHHHHHHHHHHHHTTT-EEEEEESS-THHHHHHHHTT.SEEEEEE CS
  Aminotran_1_2  31 alaggtlneygpidglpeleealakflg....rseklklkreaavvvgsGagaliealifllklnpgdeilvpdptyasyknilrlsg.gevvryp 121
                    +   + + eygp+ g ++l+ a+a++++    ++++ +++ e +v+  +G  a++  ++++l     +    p p y+ y+++l l + +  +++p
     EEA20289.1 103 IPIDSAAREYGPTAGIKSLRAAVARLYNeqyrQGKESQYTWE-NVCIVPGGRAGLIRIAAIL---GNSYLSFPIPDYTAYSEMLSLFKnFSPIPIP 194
                    55667889********************88766668889999.**********999999999...6999****************976266***** PP

                    BEETTTTEE-HHHHHHHHTTHHCTTETEEEEEEESS-TTT--B--HHHHHHHHHHHHHTTEEEEEEETTTTCBSSSS.HTHHH.......HGGSTT CS
  Aminotran_1_2 122 lyseedfhldlealeealkeapegnkktkvilvesphNPtGtvatleeleklldlakkynlllfvDeaYagfvfgsl.davat.......ranvee 209
                    l++++ +++  +++ e +++       t v+l+ +p NPtG v+  + l k+ d+++  ++ l++De Y+g  +++  d   t       +++v++
     EEA20289.1 195 LSESDHYQIHPDKIAEEIAR------GTSVLLTSNPRNPTGHVIQNPNLAKIQDICRD-RATLILDEFYGGYNYTTDcD--GTtlsgaenVVDVDQ 281
                    ********************......999****************************7.***************95554..334588776777777 PP

                    STTEEEEEESSSTTSSGGG-EEEEEEEHHHHHHHHHHHHHHTS..SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTEEEECCS CS
  Aminotran_1_2 210 epnllivgslsKafGlaGeRvGyilgnaavvsqlrklsrpfls..ssllqaavaaalsdallkqseleemrqrlqkrrkelrdeLaelglkvlasq 303
                    ++ +l+  +l K f l+G+R+++i+g +++v++l+++ + +      + q+a++ +l+ +l +++e+++ + ++ ++r+++ ++L+e+g+ + + +
     EEA20289.1 282 DD-VLLIDGLTKRFRLPGWRIAWIVGPKEFVEALASAGSYLDGgaNVPFQEAAVPMLEPSL-VKQEMKALQLHFRSKRDYVIARLREIGFRFKDIP 375
                    54.6********************************99988889999************99.567***********************99999866 PP

                    .CSSEEEEEETHH...........CHHHHHHHHHHTCTEEEEEGGGGTS.............TTEEEEECTTS-H CS
  Aminotran_1_2 304 .sgmflltdlsae...........takelskkLleevgvyvtpgtsftv.............pgrlRitvAglte 353
                     ++++ + dl+             +   ++ +Ll+e + +v+pg  f +               ++R+++ g + 
     EEA20289.1 376 eATFYIWLDLTSIepplpesanisDGLNFFNALLKE-KTIVVPGIFFDLnpakrrdlfdspcHHFVRLSY-GPKM 448
                    6**********999*********9999*********.777777777776666666666666666666666.5555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (483 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       332  (0.0185175); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.46
# Mc/sec: 3128.06
//
Query:       EEA20290.1  [L=483]
Description: aminotransferase, classes I and II, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.4e-34  119.1   0.0    2.8e-34  118.9   0.0    1.0  1  Aminotran_1_2  Aminotransferase class I and II


Domain annotation for each model (and alignments):
>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.9   0.0   1.6e-38   2.8e-34      31     353 ..     103     448 ..      78     458 .. 0.85

  Alignments for each domain:
  == domain 1  score: 118.9 bits;  conditional E-value: 1.6e-38
                    HHHHTSTTST-BTTHHHHHHHHHHHHHC....TCTTCHTTGGEGEEEESHHHHHHHHHHHHHHHTTT-EEEEEESS-THHHHHHHHTT.SEEEEEE CS
  Aminotran_1_2  31 alaggtlneygpidglpeleealakflg....rseklklkreaavvvgsGagaliealifllklnpgdeilvpdptyasyknilrlsg.gevvryp 121
                    +   + + eygp+ g ++l+ a+a++++    ++++ +++ e +v+  +G  a++  ++++l     +    p p y+ y+++l l + +  +++p
     EEA20290.1 103 IPIDSAAREYGPTAGIKSLRAAVARLYNeqyrQGKESQYTWE-NVCIVPGGRAGLIRIAAIL---GNSYLSFPIPDYTAYSEMLSLFKnFSPIPIP 194
                    55667889********************88766668889999.**********999999999...6999****************976266***** PP

                    BEETTTTEE-HHHHHHHHTTHHCTTETEEEEEEESS-TTT--B--HHHHHHHHHHHHHTTEEEEEEETTTTCBSSSS.HTHHH.......HGGSTT CS
  Aminotran_1_2 122 lyseedfhldlealeealkeapegnkktkvilvesphNPtGtvatleeleklldlakkynlllfvDeaYagfvfgsl.davat.......ranvee 209
                    l++++ +++  +++ e +++       t v+l+ +p NPtG v+  + l k+ d+++  ++ l++De Y+g  +++  d   t       +++v++
     EEA20290.1 195 LSESDHYQIHPDKIAEEIAR------GTSVLLTSNPRNPTGHVIQNPNLAKIQDICRD-RATLILDEFYGGYNYTTDcD--GTtlsgaenVVDVDQ 281
                    ********************......999****************************7.***************95554..334588776777777 PP

                    STTEEEEEESSSTTSSGGG-EEEEEEEHHHHHHHHHHHHHHTS..SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTEEEECCS CS
  Aminotran_1_2 210 epnllivgslsKafGlaGeRvGyilgnaavvsqlrklsrpfls..ssllqaavaaalsdallkqseleemrqrlqkrrkelrdeLaelglkvlasq 303
                    ++ +l+  +l K f l+G+R+++i+g +++v++l+++ + +      + q+a++ +l+ +l +++e+++ + ++ ++r+++ ++L+e+g+ + + +
     EEA20290.1 282 DD-VLLIDGLTKRFRLPGWRIAWIVGPKEFVEALASAGSYLDGgaNVPFQEAAVPMLEPSL-VKQEMKALQLHFRSKRDYVIARLREIGFRFKDIP 375
                    54.6********************************99988889999************99.567***********************99999866 PP

                    .CSSEEEEEETHH...........CHHHHHHHHHHTCTEEEEEGGGGTS.............TTEEEEECTTS-H CS
  Aminotran_1_2 304 .sgmflltdlsae...........takelskkLleevgvyvtpgtsftv.............pgrlRitvAglte 353
                     ++++ + dl+             +   ++ +Ll+e + +v+pg  f +               ++R+++ g + 
     EEA20290.1 376 eATFYIWLDLTSIepplpesanisDGLNFFNALLKE-KTIVVPGIFFDLnpakrrdlfdspcHHFVRLSY-GPKM 448
                    6**********999*********9999*********.777777777776666666666666666666666.5555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (483 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       332  (0.0185175); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.48
# Mc/sec: 2998.41
//
Query:       EEA20291.1  [L=410]
Description: thermatolerance membrane protein Dlt1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0015   18.6   0.0        1.5    8.8   0.0    2.2  2  NICE-3    NICE-3 protein
  ------ inclusion threshold ------
      0.018   15.3   0.0      0.035   14.3   0.0    1.5  1  DUF4129   Domain of unknown function (DUF4129)


Domain annotation for each model (and alignments):
>> NICE-3  NICE-3 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.7   0.0   0.00035       3.2       7      77 ..      44     119 ..      40     134 .. 0.72
   2 !    8.8   0.0   0.00017       1.5     119     179 ..     209     268 ..     203     270 .. 0.78

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00035
      NICE-3   7 nvvlvialgvlifvl.lfifakRqi.mRfalksrrgphvpiGhg.akkslkkeierrlelvskikye..Prllses 77 
                 n+ +v  + vl+++l l i+a R    R al+   ++ +p+++g + k+++ke+e++l++   i+++  Pr +s++
  EEA20291.1  44 NIFIVAGVYVLTVLLgLLIYASRIYtNRTALSGIPKAWIPVAKGeVDKKVQKEVEEGLNRSAIIAFQarPRNVSDE 119
                 66677777777777646677777532588888899999999986489***********998887765337777755 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.00017
      NICE-3 119 lgrhpgenlrsyLlrlrssplksvrkslidqlldlyehARhgpeeFgeeeylkyqelleeL 179
                 l+r++   lr+y+ +l    l  ++ +l  ++l +ye+AR+++++  e+e+ +++ ++ e+
  EEA20291.1 209 LQRPSTMGLREYIAHLTGLGL-INPPELGPEFLAIYERARFSSRPLFEDEFRALMGIFAEI 268
                 567777778888888873333.345677789********************9999887775 PP

>> DUF4129  Domain of unknown function (DUF4129)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   3.9e-06     0.035      14      65 ..     209     262 ..     204     265 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 3.9e-06
     DUF4129  14 ldrrpgeTprEyarrv....riapspaaalaalaelfeearYGgrpasaeeyrrlv 65 
                 l r+ ++  rEy +++         p +   ++++++e+ar++ rp+ ++e+r+l+
  EEA20291.1 209 LQRPSTMGLREYIAHLtglgL--INPPELGPEFLAIYERARFSSRPLFEDEFRALM 262
                 667888999999999976332..33556667899*******************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (410 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       533  (0.0297284); expected 358.6 (0.02)
Passed bias filter:                      425  (0.0237046); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.25s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 2734.04
//
Query:       EEA20292.1  [L=368]
Description: sucrase/ferredoxin-like family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.5e-69  233.1   0.0      3e-69  232.8   0.0    1.1  1  Suc_Fer-like  Sucrase/ferredoxin-like


Domain annotation for each model (and alignments):
>> Suc_Fer-like  Sucrase/ferredoxin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  232.8   0.0   1.7e-73     3e-69       1     195 []      75     357 ..      75     357 .. 0.97

  Alignments for each domain:
  == domain 1  score: 232.8 bits;  conditional E-value: 1.7e-73
  Suc_Fer-like   1 llgtvkayskhvlvatgksdWpskvedekgslaealkklk.......lllsasslp......eekseeekttvlllPdfklveevtpssveelvkef 84 
                   l+g+vk++++hvlvatgk dW+++v+dekgs++ea++k +       l+lsas++p      ++++  ++ttv+llP+fk++++vtp+ +++l+k f
    EEA20292.1  75 LYGHVKGWATHVLVATGKADWVRDVADEKGSVMEAIDKGGltpsngnLKLSASNIPvpdeyhHAEDGARPTTVVLLPAFKIIDHVTPALAPDLIKYF 171
                   79***********************************96489*****999****99*****9888999***************************** PP

  Suc_Fer-like  85 lkp.................................kvrklpekaliLvCshktrDarCgilapllrkelerelre......kederpggvrvgfis 142
                   ++p                                 ++r+lp++a+iL+Cs++trDarCg++apll++e+er+lr+       +d+rpggv v+fis
    EEA20292.1 172 VNPsittttplrsnpsetispaegvseqdissltplRSRPLPHAAVILLCSQRTRDARCGQSAPLLKREFERHLRThglyrdASDDRPGGVAVYFIS 268
                   **99********************************99*************************************9666665559************ PP

  Suc_Fer-like 143 HvGGHkfAgnviiyrkek...................................agqgiwygrvepedvegiveetilkgkvvke.llRg 195
                   HvGGHk+++nviiyr+++                                   a+qgiw++rv+pe++e+iv+ t+l+gk+vk+ +lRg
    EEA20292.1 269 HVGGHKYSANVIIYRRRDfdwhkktaysstaaaataaateeekvlpqqnedegAAQGIWLARVRPEECENIVKFTVLQGKLVKPdQLRG 357
                   ********************************************************************************99999**98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (368 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       398  (0.0221987); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.49
# Mc/sec: 2273.11
//
Query:       EEA20293.1  [L=800]
Description: G-patch domain protein (TFIP11), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.8e-85  285.9   7.6    3.8e-85  285.9   7.6    1.6  2  GCFC            GC-rich sequence DNA-binding factor-like prot
    4.9e-16   58.4   2.6    1.2e-15   57.2   2.6    1.7  1  G-patch         G-patch domain
    2.3e-07   30.8   2.3      1e-06   28.7   2.3    2.1  1  G-patch_2       G-patch domain


Domain annotation for each model (and alignments):
>> GCFC  GC-rich sequence DNA-binding factor-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       0.6   3.6e+03     137     152 ..     276     291 ..     272     323 .. 0.67
   2 !  285.9   7.6   6.4e-89   3.8e-85       2     277 .]     338     624 ..     337     624 .. 0.95

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 0.6
        GCFC 137 LeaaveeWdPlskkqt 152
                 Lea+v+eW+ l+++++
  EEA20293.1 276 LEAFVDEWKGLTERKK 291
                 6677777777777663 PP

  == domain 2  score: 285.9 bits;  conditional E-value: 6.4e-89
        GCFC   2 eeiaekFeelkekyleeykeaelselavslvaPllrealleWePLkdptalvdnlkswrklLe....eevkekekkrkesttpyetllwelwlpsvrss 96 
                 ee+++k+e ++ +y + ++e++ls+ av++++Pl+rea++eWePLkdpt+lv+ l ++ +lL+    + ++e+  ++++st+pye+l++++wlp+vrs 
  EEA20293.1 338 EEVTSKLELIEVEYRDIIDEYRLSDAAVAAIHPLFREAMEEWEPLKDPTFLVADLLRLLPLLSrksqQIEDESVPRHRQSTSPYESLIYSIWLPRVRSV 436
                 789************************************************************7644333445557899******************** PP

        GCFC  97 vanewdprdpdpmlalleaWkplLPefvldnlleqlilpkLeaaveeWdPlskkqttrlvpih...swifpwlpllgeerlep....glvsdirrklrq 188
                 + newd+++p+p+++l+ aWk+++P+fv++n+l+q+i+pkL+aa++eW+P+s++++ ++++     +w+f+wl++l+e++++p    gl+sd+rrk+r 
  EEA20293.1 437 LLNEWDVYEPSPATSLVVAWKDVIPTFVYSNILNQVIVPKLSAAIKEWKPRSSRRHPESSQGSrfpWWLFTWLQYLDERHTNPrhatGLLSDVRRKFRV 535
                 ******************************************************988777665677********************************* PP

        GCFC 189 aLdaWdpsrsalaiLkpWkdvfspaewdklllrhilpklaralq.efeinpkqqslellenvlkWkdllspsvlaeLlekeffpkwlqvl 277
                 +Ld+Wd++++ l + + Wk+++ + e+d+ l++h+lp+lar+l+ +fe+np++q+l+++e vlkWkdl++p+v+  Ll++effpkw+++l
  EEA20293.1 536 VLDTWDLRKGLLNGVDLWKEALGS-EFDAALHKHLLPRLARHLReNFEVNPQDQDLTAFEDVLKWKDLYKPKVFGLLLVAEFFPKWHNIL 624
                 ************************.**************************************************************986 PP

>> G-patch  G-patch domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.2   2.6   1.9e-19   1.2e-15       2      44 ..     109     151 ..     108     152 .. 0.97

  Alignments for each domain:
  == domain 1  score: 57.2 bits;  conditional E-value: 1.9e-19
     G-patch   2 sniGvkmLqkmGWkpGqGLGkkeqGiaePieakikkdraGlGa 44 
                 ++++++m++kmG+ +GqGLG+ + Gi++Piea+ +++r GlGa
  EEA20293.1 109 NSFAARMMAKMGYVEGQGLGEGGRGIVNPIEAQGRPQRIGLGA 151
                 799***************************************9 PP

>> G-patch_2  G-patch domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.7   2.3   1.7e-10     1e-06      16      59 ..     110     153 ..     106     155 .. 0.94

  Alignments for each domain:
  == domain 1  score: 28.7 bits;  conditional E-value: 1.7e-10
   G-patch_2  16 eFGaAlLrGMGWkegqgigknkkgrvkpeepkrRpgrlGLGakp 59 
                 +F a ++  MG+ egqg g+ + g v+p+e + Rp+r GLGa +
  EEA20293.1 110 SFAARMMAKMGYVEGQGLGEGGRGIVNPIEAQGRPQRIGLGAVK 153
                 69999************************************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (800 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1445  (0.0805957); expected 358.6 (0.02)
Passed bias filter:                      752  (0.0419432); expected 358.6 (0.02)
Passed Vit filter:                        67  (0.00373696); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.80u 0.31s 00:00:01.11 Elapsed: 00:00:00.46
# Mc/sec: 5187.91
//
Query:       EEA20294.1  [L=230]
Description: Mn superoxide dismutase SodB [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.1e-36  123.2   0.4      6e-36  122.7   0.4    1.3  1  Sod_Fe_C  Iron/manganese superoxide dismutases, C-terminal do
    7.1e-28   96.9   0.5    1.2e-27   96.2   0.5    1.4  1  Sod_Fe_N  Iron/manganese superoxide dismutases, alpha-hairpin


Domain annotation for each model (and alignments):
>> Sod_Fe_C  Iron/manganese superoxide dismutases, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  122.7   0.4   6.7e-40     6e-36       1     102 []     126     227 ..     126     227 .. 0.96

  Alignments for each domain:
  == domain 1  score: 122.7 bits;  conditional E-value: 6.7e-40
                 --HHHHHHHHHHHSSHHHHHHHHHHHHHHSSSSEEEEEEEETT.TEEEEEEEETTTBGGGGTTCEEEEEE-SGGGTHHHHTT-HHHHHHHHGGGBBHHH CS
    Sod_Fe_C   1 psgelaeaieedfgslekfkkefkaaalavfgsGwawLvldkk.kkLeivttknqdnplvkeakplLalDvwehAYyldyqnkradYieafwnvvnWke 98 
                 psg l +ai+e++gs+ +f+++f++a ++++gsGwawLv+dk+ ++++i t +nqd p+v + +plL++D wehAYyl+yqn++a+Y++a+w+v+nWk+
  EEA20294.1 126 PSGVLGKAIDETYGSFGEFQNKFNTALAGIQGSGWAWLVKDKEtGDISIKTYANQD-PVVGQYTPLLGVDAWEHAYYLQYQNRKAEYFKAIWEVLNWKA 223
                 7899************************************998679********99.6888999*********************************** PP

                 HHHH CS
    Sod_Fe_C  99 veer 102
                 +e+r
  EEA20294.1 224 AEKR 227
                 *987 PP

>> Sod_Fe_N  Iron/manganese superoxide dismutases, alpha-hairpin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   96.2   0.5   1.3e-31   1.2e-27       3      82 .]      37     116 ..      35     116 .. 0.98

  Alignments for each domain:
  == domain 1  score: 96.2 bits;  conditional E-value: 1.3e-31
                 -----SS-TTTTTTTS-HHHHHHHHHTHHHHHHHHHHHHHHCHHHHCHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTB- CS
    Sod_Fe_N   3 eLpeLpYaydaLePhisketlelHhdkHhktYvnnlNkalekleeakkkleelvlkklekalrnnagghvnHslfwknls 82 
                 +Lp+L Y+y aLeP +s +++e+Hh+ Hh+ Yv ++N+ +ekleea++k +  ++ +l+  +++++ggh+nHslfw+nl+
  EEA20294.1  37 TLPDLAYDYGALEPSVSGKIMEIHHKGHHNVYVAGYNTNIEKLEEAQAKGDIAAQIALKPLINFHGGGHINHSLFWENLA 116
                 8*****************************************************************************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (230 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       353  (0.0196888); expected 358.6 (0.02)
Passed bias filter:                      293  (0.0163422); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1537.72
//
Query:       EEA20295.1  [L=230]
Description: Mn superoxide dismutase SodB [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.1e-36  123.2   0.4      6e-36  122.7   0.4    1.3  1  Sod_Fe_C  Iron/manganese superoxide dismutases, C-terminal do
    7.1e-28   96.9   0.5    1.2e-27   96.2   0.5    1.4  1  Sod_Fe_N  Iron/manganese superoxide dismutases, alpha-hairpin


Domain annotation for each model (and alignments):
>> Sod_Fe_C  Iron/manganese superoxide dismutases, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  122.7   0.4   6.7e-40     6e-36       1     102 []     126     227 ..     126     227 .. 0.96

  Alignments for each domain:
  == domain 1  score: 122.7 bits;  conditional E-value: 6.7e-40
                 --HHHHHHHHHHHSSHHHHHHHHHHHHHHSSSSEEEEEEEETT.TEEEEEEEETTTBGGGGTTCEEEEEE-SGGGTHHHHTT-HHHHHHHHGGGBBHHH CS
    Sod_Fe_C   1 psgelaeaieedfgslekfkkefkaaalavfgsGwawLvldkk.kkLeivttknqdnplvkeakplLalDvwehAYyldyqnkradYieafwnvvnWke 98 
                 psg l +ai+e++gs+ +f+++f++a ++++gsGwawLv+dk+ ++++i t +nqd p+v + +plL++D wehAYyl+yqn++a+Y++a+w+v+nWk+
  EEA20295.1 126 PSGVLGKAIDETYGSFGEFQNKFNTALAGIQGSGWAWLVKDKEtGDISIKTYANQD-PVVGQYTPLLGVDAWEHAYYLQYQNRKAEYFKAIWEVLNWKA 223
                 7899************************************998679********99.6888999*********************************** PP

                 HHHH CS
    Sod_Fe_C  99 veer 102
                 +e+r
  EEA20295.1 224 AEKR 227
                 *987 PP

>> Sod_Fe_N  Iron/manganese superoxide dismutases, alpha-hairpin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   96.2   0.5   1.3e-31   1.2e-27       3      82 .]      37     116 ..      35     116 .. 0.98

  Alignments for each domain:
  == domain 1  score: 96.2 bits;  conditional E-value: 1.3e-31
                 -----SS-TTTTTTTS-HHHHHHHHHTHHHHHHHHHHHHHHCHHHHCHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTB- CS
    Sod_Fe_N   3 eLpeLpYaydaLePhisketlelHhdkHhktYvnnlNkalekleeakkkleelvlkklekalrnnagghvnHslfwknls 82 
                 +Lp+L Y+y aLeP +s +++e+Hh+ Hh+ Yv ++N+ +ekleea++k +  ++ +l+  +++++ggh+nHslfw+nl+
  EEA20295.1  37 TLPDLAYDYGALEPSVSGKIMEIHHKGHHNVYVAGYNTNIEKLEEAQAKGDIAAQIALKPLINFHGGGHINHSLFWENLA 116
                 8*****************************************************************************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (230 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       353  (0.0196888); expected 358.6 (0.02)
Passed bias filter:                      293  (0.0163422); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.27s 00:00:00.69 Elapsed: 00:00:00.42
# Mc/sec: 1651.50
//
Query:       EEA20296.1  [L=364]
Description: mannose-1-phosphate guanylyltransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.2e-52  179.0   0.0    2.4e-52  178.0   0.0    1.5  2  NTP_transferase  Nucleotidyl transferase
    1.3e-14   53.3   6.7    3.4e-11   42.4   1.7    3.1  2  Hexapep          Bacterial transferase hexapeptide (six repea
    1.6e-09   38.3   0.0    2.4e-09   37.8   0.0    1.3  1  NTP_transf_3     MobA-like NTP transferase domain
    1.4e-06   27.9   6.9    1.9e-06   27.5   0.9    3.0  3  Hexapep_2        Hexapeptide repeat of succinyl-transferase
  ------ inclusion threshold ------
      0.028   12.6   0.2      0.047   11.8   0.2    1.3  1  DUF4954          Domain of unknown function (DUF4954)
       0.15   11.7   0.0       0.26   10.9   0.0    1.3  1  SRP54            SRP54-type protein, GTPase domain
       0.17   11.6   0.0       0.28   10.9   0.0    1.3  1  IspD             2-C-methyl-D-erythritol 4-phosphate cytidyly


Domain annotation for each model (and alignments):
>> NTP_transferase  Nucleotidyl transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  178.0   0.0   9.2e-56   2.4e-52       1     242 [.       2     230 ..       2     236 .. 0.95
   2 ?   -2.7   0.0       1.3   3.4e+03     101     117 ..     322     338 ..     315     342 .. 0.77

  Alignments for each domain:
  == domain 1  score: 178.0 bits;  conditional E-value: 9.2e-56
                      EEEEE--S--GGGTTCCTTSSGGGSEETTETETTHHHHHHHHHTT-SEEEEEEETTTHHHHHHHHTTSGGGTSEEEEEEESS--BGGHHHHHTH CS
  NTP_transferase   1 kavILaGGsGtRLwPLtrtlakklvpvlgkerliqatlsrlansgieeiivvltqehsflveeqlkegskfgvevlialepegkgtAdAvalaa 94 
                      ka+IL+GG GtRL+PLt tl+k+lv +++  ++i ++++ la++g+++i++ ++++   +v    k ++++++++++++e+e+ gtA++++la+
       EEA20296.1   2 KALILVGGFGTRLRPLTLTLPKPLVEFGNR-PMILHQVESLAAAGVTDIVLAVNYRPDVMVSALKKYEEQYNINIEFSVESEPLGTAGPLKLAE 94 
                      799***************************.*************************************************************** PP

                      HHHTTSSE..EEEEETTEEEESTTHHHHHHHHHTHSSTTSEEEEEEESS-CTTSEEEEECTTS..BEEEEECS-SSHSHCSEECCSEEEEETTH CS
  NTP_transferase  95 elledeksdelvlvLggDhlikdayeeavkkaiekaakgtvtfgivpveeateyGvieadeeg..rverfvEKPkeakaselassGiYvfnsev 186
                      ++l++++s   ++vL++D+++++ ++++ +++++++   + t+++++v+e+++yGv+ ++ ++  r+ rfvEKP e    + +++GiY+ n++v
       EEA20296.1  95 KILGKDDS--PFFVLNSDVICEYPFKQLAEFHKSHGD--EGTIVVTKVDEPSKYGVVVHKPNHpsRIDRFVEKPVEFV-GNRINAGIYILNPSV 183
                      ******98..9**************************..99*******************77777*************.9************** PP

                      HHHHHHCCHHHTTSSCHHHHHHHHHHHTTEEEEEECSTTEE-EEEXSSHHHHHHHH CS
  NTP_transferase 187 llflakdleelkrgedeitdilpkaleegkvalaflfkdaeyWsDvGtldsllean 242
                      l+ +     el r ++  ++++p++++egk + +f+ ++   W+DvG+++++l  +
       EEA20296.1 184 LKRI-----EL-RPTSIEQETFPAIVKEGKLH-SFDLEG--FWMDVGQPKDFLSGT 230
                      ****.....44.566777899********999.78****..6**********9765 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 1.3
                      SE..EEEEETTEEEEST CS
  NTP_transferase 101 ksdelvlvLggDhlikd 117
                      ++ e+v vLg+D+ i d
       EEA20296.1 322 ARLENVTVLGDDVTIAD 338
                      4567899*****99987 PP

>> Hexapep  Bacterial transferase hexapeptide (six repeats)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.4   1.7   1.3e-14   3.4e-11       1      34 [.     263     296 ..     263     298 .. 0.94
   2 !   12.4   0.3     4e-05       0.1       2      36 .]     310     344 ..     309     348 .. 0.87

  Alignments for each domain:
  == domain 1  score: 42.4 bits;  conditional E-value: 1.3e-14
                 TEEEETTEEE-TTEEEETTEEE-TTEEEETTEEE CS
     Hexapep   1 stvIGsnvlIgpfaviggnVkIGdnvkIgagvvi 34 
                 s++IG+n+ Igp++vig+nV++Gd+v++ ++v +
  EEA20296.1 263 SAKIGKNCRIGPNVVIGPNVVVGDGVRLQRCVLL 296
                 689***************************9987 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 4e-05
                 EEEETTEEE-TTEEEETTEEE-TTEEEETTEEEES CS
     Hexapep   2 tvIGsnvlIgpfaviggnVkIGdnvkIgagvvigg 36 
                 t++G n+ +g++a + + +++Gd+v+I+  v+++g
  EEA20296.1 310 TIVGWNSSVGKWARLENVTVLGDDVTIADEVYVNG 344
                 67777899999999999999999999999888875 PP

>> NTP_transf_3  MobA-like NTP transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.8   0.0   9.2e-13   2.4e-09       1     122 [.       3     135 ..       3     210 .. 0.73

  Alignments for each domain:
  == domain 1  score: 37.8 bits;  conditional E-value: 9.2e-13
                   EEEEEESS-TTTTT.....THHHHCCCCCCHHHHHHHHHCTT.-CEEEEECSHC......HHHHHHTTC..TS-EEE-TTS..S-SHHHHHHHHHHH CS
  NTP_transf_3   1 aviLAGGrSsRmgg.....dKallplggkpllervldalraagvdevvvvggde......evlaalarl..gvrvvededp..gkgplaslaaalra 82 
                   a+iL GG ++R+       +K+l+++g++p++ +++++l+aagv ++v++++++      +++++ +++  ++++ ++++p   +gpl+     l +
    EEA20296.1   3 ALILVGGFGTRLRPltltlPKPLVEFGNRPMILHQVESLAAAGVTDIVLAVNYRpdvmvsALKKYEEQYniNIEFSVESEPlgTAGPLKLAEKILGK 99 
                   79**********8444668*********************************953443332222323333334444444432234555544444443 PP

                   H.SSSCEEEEETT-TT--HHHHHHHHHCHHHHTSSEEEEE CS
  NTP_transf_3  83 aadadavlvlacDmPlltpelverllaaaaasgadvvvpt 122
                     d+++++vl  D+++  +   ++l++ ++++g++ ++++
    EEA20296.1 100 --DDSPFFVLNSDVIC--EYPFKQLAEFHKSHGDEGTIVV 135
                   ..78899999999977..5556677766666665443333 PP

>> Hexapep_2  Hexapeptide repeat of succinyl-transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       2.5   6.5e+03      26      32 ..     172     178 ..     171     179 .. 0.81
   2 !   27.5   0.9   7.4e-10   1.9e-06       3      26 ..     265     290 ..     263     292 .. 0.93
   3 ?    2.8   0.1     0.039        99       9      31 ..     311     341 ..     308     345 .. 0.69

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 2.5
                 E-TT-EE CS
   Hexapep_2  26 vgaGvvi 32 
                 + aG++i
  EEA20296.1 172 INAGIYI 178
                 6799998 PP

  == domain 2  score: 27.5 bits;  conditional E-value: 7.4e-10
                 EE-TT-EE-TT-EES..EEE-TT-EE CS
   Hexapep_2   3 iIGdnCliGanagiG..vslGdncvv 26 
                 +IG+nC iG+n +iG  v +Gd++ +
  EEA20296.1 265 KIGKNCRIGPNVVIGpnVVVGDGVRL 290
                 8*************999******987 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.039
                 EE-TT-EES........EEE-TT-EE-TT-E CS
   Hexapep_2   9 liGanagiG........vslGdncvvgaGvv 31 
                 ++G n+ +G        + lGd+++++  v+
  EEA20296.1 311 IVGWNSSVGkwarlenvTVLGDDVTIADEVY 341
                 55666666666666666899***99985555 PP

>> DUF4954  Domain of unknown function (DUF4954)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.2   1.8e-05     0.047     190     263 ..     257     327 ..     255     348 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 1.8e-05
     DUF4954 190 NvkigdyatiegasklengtinSskeapveiGegViledfiissGskikdgavisrcfvGqavklkkqfsaeds 263
                 Nv++++ a+i    ++    ++      v +G+gV l+ +++ + sk+kd a ++ ++vG + +++k +++e+ 
  EEA20296.1 257 NVMVDPSAKIGKNCRIGPNVVIG---PNVVVGDGVRLQRCVLLENSKVKDHAWVKSTIVGWNSSVGKWARLENV 327
                 55555555555555554333332...34889***********************************99999985 PP

>> SRP54  SRP54-type protein, GTPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0    0.0001      0.26     113     174 ..      99     169 ..      89     173 .. 0.72

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.0001
                 SSSEEEEEEET.TBHTHHHHHHHHHHHHSSCSE.EEEESTTSSSSTTHHH.......HHHHHHTS-EEEEE CS
       SRP54 113 kpdevllvlda.ttgqeavkqakaFkeavgitg.viltklDgdakgGaal.......siaaelklPikfig 174
                 k+d+ ++vl++ ++ +  +kq  +F+++ g +g +++tk+D+ +k G ++        i + +++P+ f+g
  EEA20296.1  99 KDDSPFFVLNSdVICEYPFKQLAEFHKSHGDEGtIVVTKVDEPSKYGVVVhkpnhpsRIDRFVEKPVEFVG 169
                 56666777776245666789999***99977662678***********98444333347777788888877 PP

>> IspD  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00011      0.28       2      54 ..       2      56 ..       1      72 [. 0.80

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00011
                EEEEECTTSSCTT-...SSS-GGGSEETTEEHHHHHHHHHHCTTTEEEEEEEE-GG CS
        IspD  2 vvvipAAGsGkRmk...aglpKqflelkgqtllehtvdallaskavdkivvvvsed 54
                 ++i   G+G+R++     lpK ++e  +++++ h v++l+a   v  iv++v+  
  EEA20296.1  2 KALILVGGFGTRLRpltLTLPKPLVEFGNRPMILHQVESLAA-AGVTDIVLAVNYR 56
                5788899*****86222689********************99.6677788888754 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (364 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       287  (0.0160076); expected 358.6 (0.02)
Passed bias filter:                      275  (0.0153383); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2638.85
//
Query:       EEA20297.1  [L=447]
Description: MFS monocarboxylate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.8e-32  111.6  73.9    3.9e-25   88.5  34.9    2.1  2  MFS_1     Major Facilitator Superfamily
    4.2e-12   45.7  32.5    1.3e-06   27.6   8.8    2.2  2  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.5  34.9   4.3e-29   3.9e-25       4     293 ..      67     344 ..      58     352 .. 0.79
   2 !   37.0  31.0     2e-13   1.8e-09       5     170 ..     269     433 ..     268     442 .. 0.86

  Alignments for each domain:
  == domain 1  score: 88.5 bits;  conditional E-value: 4.3e-29
       MFS_1   4 aaflsalarsilgpalplalaedlg...ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll.fasslw.lllvlrvlqGl 97 
                 +++++++++ +++ ++  +++++      s+s+i ++ ++  ++++ a l+ G+l+dr+G++++l+ + llf+l+ ++l+ ++ +++ ++l+  +l Gl
  EEA20297.1  67 CIMFNTFGYINAFGIFEAYYKST-MmphESHSSIAWIGSIQVFFMFSAGLISGPLMDRYGPKPILIPCSLLFILS-IMLTsLCRQYYqFILAQGILGGL 163
                 44444444444444444333333.134479999******************************************.55554778888799999999999 PP

       MFS_1  98 gagalfpagaaliadwfpkeergraigllsagfslGailgpllgg.lla.sslgWravfyilaivsllafvlfllllpeepperkrkspkeeekgtgpa 194
                 + g+ ++ ++a++ ++f k +r++a+g++s+g+s++ i  p++   ll  + +g+ ++  +l++v+l++ v++ l +  ++p+r+     ++       
  EEA20297.1 164 TNGLTYTPALAAVGHYFLK-KRPLAMGIASTGASISGITLPIALNrLLNrTTVGFGWSVRVLGFVMLVLSVIACLSVSSNAPKRRSG--PPL------- 252
                 99*****************.*****************99976555388899999***************998444444444444444..333....... PP

       MFS_1 195 plvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglal 293
                  l +awk    +      +++ +l++++++  +++lp +  +  gl+ + l+ +lla+l +++++++ll+g+ +dr+gr ++l +a+l++ ++ l+++ 
  EEA20297.1 253 LL-KAWKNRAYSL----QVAGTFLVMWAVFVPFFYLPGF-GQSIGLT-VDLSFYLLAILNAASLFGRLLGGAAADRMGRINTLSFACLICGVLILCWLG 344
                 22.3366555555....88899999899999*******9.*******.888888899999999999*************77777776666666666654 PP

  == domain 2  score: 37.0 bits;  conditional E-value: 2e-13
       MFS_1   5 aflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.sslwlllvlrvlqGlgagal 102
                 +fl+++a ++ ++ lp   +++ g++++    ll++  ++++++ l++G+ +dr+Gr  +l ++ l+ ++  +l++++ +s+ + +++ +l G+++g++
  EEA20297.1 269 TFLVMWAVFVPFFYLP-GFGQSIGLTVDLSFYLLAILNAASLFGRLLGGAAADRMGRINTLSFACLICGVL-ILCWLGiQSHGATIAFAALFGFFSGTV 365
                 7889999999999999.***********9999***************************999999999999.44443437777**************** PP

       MFS_1 103 fpagaaliadwfpk.eergraigllsagfslGailgpllgglla.sslgWravfyilaivsllafvlfll 170
                 +++  a ia  +p+ +e g+++g++ + +s++ + g ++ g+++ ++ +++ +  ++++ +ll++++  +
  EEA20297.1 366 IAVFPATIAMTAPQpNEIGSYLGMALGVYSFAGLSGTPITGAMInDYNSYHPAIAFAGVSALLGAMI--I 433
                 **************99********************8888888857777877777777777777553..2 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.6   8.8   1.5e-10   1.3e-06      20     185 ..      71     236 ..      61     240 .. 0.77
   2 !   20.1  20.4   2.7e-08   0.00025      43     190 ..     248     435 ..     213     444 .. 0.78

  Alignments for each domain:
  == domain 1  score: 27.6 bits;  conditional E-value: 1.5e-10
                 GGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHH.HHHHH CS
    Sugar_tr  20 gafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlv.GigvG 117
                 ++f ++++f  ++ ++ks+ +  es + + +i si ++  +  +l++g+l+dr+G k++l+ +++lf+ +++l+ ++    +++++i+++ ++ G+  G
  EEA20297.1  71 NTFGYINAFGIFEAYYKSTMMPHESHSSIAWIGSIQVFFMFSAGLISGPLMDRYGPKPILIPCSLLFILSIMLTSLCR---QYYQFILAQGILgGLTNG 166
                 556666677777777777777777888899************************************************...899999997655178888 PP

                 HHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-..TTHHHHHHHCCHHHHHHHH CS
    Sugar_tr 118 lasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsn..adgwrillglqlvpallll 185
                 l+++ +   ++ +  kk   a++     a + Gi + + ++  ln+t+    +  r+l ++ lv++++ +
  EEA20297.1 167 LTYTPALAAVGHYFLKKRPLAMGIASTGASISGITLPIALNRLLNRTTVgfGWSVRVLGFVMLVLSVIAC 236
                 8888777777777766666777777777777777777777777766666344444555566666665555 PP

  == domain 2  score: 20.1 bits;  conditional E-value: 2.7e-08
                 H...............................................HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TT CS
    Sugar_tr  43 e...........................................ssv.lsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaak 97 
                 +                                           ++v ls  +++i+++ +++G l++g ++dr+GR ++l +a++++ + +++   ++
  EEA20297.1 248 SgpplllkawknrayslqvagtflvmwavfvpffylpgfgqsigLTVdLSFYLLAILNAASLFGRLLGGAAADRMGRINTLSFACLICGVLILCWLGIQ 346
                 2555555555555555555555555555555555555555555555514556789*********************************99999999999 PP

                 TTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS..-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGG CS
    Sugar_tr  98 gknsvevlivgRvlvGigvGlasvlvPmyisEiA..pkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllf 190
                    s+ + i+   l G++ G++ ++ P +i+  A  p ++ ++l++   +   +G   + i+g+ +n++++   ++  ++++ v+all +++++ 
  EEA20297.1 347 ---SHGATIAFAALFGFFSGTVIAVFPATIAMTApqPNEIGSYLGMALGVYSFAGLSGTPITGAMINDYNS---YHPAIAFAGVSALLGAMIIFA 435
                 ...9******************************7778999******************************...999999999999888777664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (447 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       661  (0.0368676); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.27s 00:00:00.86 Elapsed: 00:00:00.45
# Mc/sec: 2997.73
//
Query:       EEA20298.1  [L=336]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
       0.12   12.3   0.0       0.21   11.5   0.0    1.4  1  REPA_OB_2  Replication protein A OB domain


Domain annotation for each model (and alignments):
>> REPA_OB_2  Replication protein A OB domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   1.2e-05      0.21      15      66 ..     172     223 ..     164     256 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 1.2e-05
   REPA_OB_2  15 vigvvksveevseitskstekelkkreltlvDesgasvevtlWgkeaekfes 66 
                 ++  v  +++++++t++++++el+  el + De+ +   vt+W    e+ ++
  EEA20298.1 172 LVVAVMGINPLRRVTARQSKQELDILELIVGDETRTGFGVTFWLPVPENQKQ 223
                 56667889***********************************874433333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (336 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       360  (0.0200792); expected 358.6 (0.02)
Passed bias filter:                      333  (0.0185733); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.24s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 2294.25
//
Query:       EEA20299.1  [L=354]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
      0.012   15.2   0.0      0.021   14.4   0.0    1.4  1  NopRA1     Nucleolar pre-ribosomal-associated protein 1
       0.13   12.2   0.0       0.23   11.4   0.0    1.4  1  REPA_OB_2  Replication protein A OB domain


Domain annotation for each model (and alignments):
>> NopRA1  Nucleolar pre-ribosomal-associated protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   2.4e-06     0.021     137     199 ..     291     352 ..     272     353 .. 0.93

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 2.4e-06
      NopRA1 137 adGlrtksDlkllkrrrvfelllslynsplldaklrelilelllratrieggattLitrsGll 199
                 a G  t++D  l+k r+v ++ll+++  ++   + +++ l++ll ++++ + +  Li++sG++
  EEA20299.1 291 AIGTTTREDKLLCKVRNVRDWLLNFVGTKARHGSHNSSALQILLPTCQL-NLSGGLIKSSGII 352
                 56899****99**************************************.7999999999986 PP

>> REPA_OB_2  Replication protein A OB domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   2.6e-05      0.23      15      66 ..     172     223 ..     164     256 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 2.6e-05
   REPA_OB_2  15 vigvvksveevseitskstekelkkreltlvDesgasvevtlWgkeaekfes 66 
                 ++  v  +++++++t++++++el+  el + De+ +   vt+W    e+ ++
  EEA20299.1 172 LVVAVMGINPLRRVTARQSKQELDILELIVGDETRTGFGVTFWLPVPENQKQ 223
                 56667889***********************************874433333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (354 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       251  (0.0139997); expected 358.6 (0.02)
Passed bias filter:                      224  (0.0124937); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 2439.95
//
Query:       EEA20300.1  [L=788]
Description: intermembrane space AAA protease IAP-1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.1e-57  193.1   0.4    7.8e-57  192.2   0.4    1.5  1  Peptidase_M41  Peptidase family M41
    1.6e-42  145.0   0.0    4.2e-42  143.7   0.0    1.8  1  AAA            ATPase family associated with various cellular
      1e-12   47.6   0.0    2.7e-12   46.3   0.0    1.8  1  AAA_lid_3      AAA+ lid domain
    8.1e-06   25.9   0.0    2.4e-05   24.3   0.0    1.8  1  AAA_5          AAA domain (dynein-related subfamily)
    4.9e-05   22.7   0.1    0.00013   21.3   0.0    1.7  2  TIP49          TIP49 P-loop domain
    5.2e-05   23.7   0.8    0.00059   20.3   0.8    2.5  1  AAA_16         AAA ATPase domain
    0.00018   21.8   1.6      0.029   14.7   0.2    3.1  2  AAA_22         AAA domain
    0.00031   20.5   0.0    0.00092   19.0   0.0    1.8  2  RuvB_N         Holliday junction DNA helicase RuvB P-loop dom
     0.0038   17.4   0.0      0.014   15.6   0.0    2.1  1  AAA_33         AAA domain
     0.0085   15.3   0.0      0.016   14.3   0.0    1.4  1  DUF815         Protein of unknown function (DUF815)
  ------ inclusion threshold ------
      0.011   15.5   0.0       0.02   14.7   0.0    1.4  1  IstB_IS21      IstB-like ATP binding protein
      0.016   15.3   0.0      0.049   13.7   0.0    1.8  1  AAA_2          AAA domain (Cdc48 subfamily)
      0.025   14.0   0.2       0.05   13.0   0.2    1.4  1  Mg_chelatase   Magnesium chelatase, subunit ChlI
      0.027   14.0   2.4       0.59    9.7   0.3    2.4  2  AAA_25         AAA domain
      0.035   14.7   0.0      0.093   13.3   0.0    1.7  1  AAA_18         AAA domain
      0.051   12.9   0.1        1.5    8.1   0.0    2.6  2  ATPase         KaiC
      0.055   13.4   0.4        1.8    8.4   0.1    2.7  2  NACHT          NACHT domain
      0.072   13.3   0.0       0.19   11.9   0.0    1.8  1  AAA_28         AAA domain
      0.087   13.3   0.3       0.25   11.8   0.0    1.9  1  AAA_17         AAA domain
       0.11   12.8   0.3         20    5.6   0.5    2.7  2  SpoU_sub_bind  RNA 2'-O ribose methyltransferase substrate bi
       0.16   11.5   0.1       0.45   10.0   0.1    1.8  1  AAA_7          P-loop containing dynein motor region


Domain annotation for each model (and alignments):
>> Peptidase_M41  Peptidase family M41
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  192.2   0.4   9.2e-60   7.8e-57       1     191 []     567     746 ..     567     746 .. 0.97

  Alignments for each domain:
  == domain 1  score: 192.2 bits;  conditional E-value: 9.2e-60
                    XX--HHHHHHHHHHHHHHHHHHCCSSS-S-B--EES--TTS-----------TSS--BHHHHHHHHHHHHHHHHHHHHHHH..S-BGGGHHHHHHH CS
  Peptidase_M41   1 rvisekekklvAyHEaGHalvglllkeadpveKvtiiPRgqalGltlslPeedklsltkeellarlavllGGraaEelifg..evttGasnDleka 94 
                    r+i++k+k l+AyHEaGHalv+++ ++a+p++K+ti+PRg+alG+t++lPe+d +s +  e+l+ ++v++GG+aaEel+fg  +vt+G s D+++a
     EEA20300.1 567 RIIQDKDKLLTAYHEAGHALVAYFSPSATPLYKITIVPRGMALGITHFLPEMDMVSRNYVEYLSDIDVAMGGKAAEELVFGpdKVTSGISADIQSA 662
                    5899**************************************************99**************************************** PP

                    HHHHHHHHHTS---TTT-S--------..----.------SS-HHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHSEE-HHHHHH CS
  Peptidase_M41  95 tkiarkmvtefGmsdklGpvsleeeeeeevflgkelkkekelseetaeeideevkelveeayerakeileekreelealaeaLlekEtldaeeiee 190
                    t+ a ++vt+fG s+klG+v l+++ +             +ls+et++ei++e+++lvee  +ra++il+ekr+ele l++aL+e+Etl++ee+e+
     EEA20300.1 663 TETAFTLVTQFGYSKKLGNVDLSTNYD-------------KLSSETKQEIEAEIRRLVEEGRSRATKILTEKRKELELLTKALIEYETLTKEEMEK 745
                    *********************887555.............58****************************************************98 PP

                    H CS
  Peptidase_M41 191 l 191
                    +
     EEA20300.1 746 V 746
                    6 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  143.7   0.0   4.9e-45   4.2e-42       1     131 [.     357     486 ..     357     487 .. 0.97

  Alignments for each domain:
  == domain 1  score: 143.7 bits;  conditional E-value: 4.9e-45
                 EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTS CS
         AAA   1 vllyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksrsgseseeeervvnqLlteldgvkkk 99 
                 vll+GppGtGKTlla+ava e+gv+f+ +sgse+ + yvg ++k++r+lf++a++ka p i+fiDE+da++ +r++++    ++++nqLlteldg+++ 
  EEA20300.1 357 VLLVGPPGTGKTLLARAVAGEAGVPFFYMSGSEFDEVYVGVGAKRVRDLFAQARAKA-PAIIFIDELDAIGAKRNERDAAYVKQTLNQLLTELDGFSQT 454
                 79******************************************************9.****************999*********************7 PP

                 SSTEEEEEEESSGGGSTHHHHS.TTSSEEEETT CS
         AAA 100 eskvivigatnrpdkldpallr.gRfdrkieie 131
                  s vi+++atn+p+ ld+al r gRfdr++ ++
  EEA20300.1 455 -SGVIILAATNYPQLLDKALTRpGRFDRRVVVG 486
                 .55*************************99876 PP

>> AAA_lid_3  AAA+ lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.3   0.0   3.2e-15   2.7e-12       1      44 [.     509     552 ..     509     553 .. 0.97

  Alignments for each domain:
  == domain 1  score: 46.3 bits;  conditional E-value: 3.2e-15
   AAA_lid_3   1 dvdlkeLAerTeGySGADlaalcreAallAlrrgikeitmedfe 44 
                 dvd++ +A+ T+G+SGADl++l++ Aa +A r++++ ++ +df+
  EEA20300.1 509 DVDVAVIARGTPGFSGADLENLVNQAAVHASRHKEDRVGPKDFD 552
                 9***************************************9995 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.3   0.0   2.8e-08   2.4e-05       1      77 [.     356     425 ..     356     432 .. 0.83

  Alignments for each domain:
  == domain 1  score: 24.3 bits;  conditional E-value: 2.8e-08
                 EEEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--.........--------G-SEEEEESGGG- CS
       AAA_5   1 dvlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreikngttslvdsplvraaregeilvlDEvera 77 
                 +vlLvGppGtgK+ la+ +a   + +++y+ +++       + ++ +  g ++ +d  +   a+ ++i+++DE++ +
  EEA20300.1 356 GVLLVGPPGTGKTLLARAVAGEAGVPFFYMSGSE-------FDEVYVGVGAKRVRDLFAQARAKAPAIIFIDELDAI 425
                 59******************************99.......344444445677788888888889999999999865 PP

>> TIP49  TIP49 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.0   1.5e-07   0.00013      51      88 ..     355     390 ..     328     410 .. 0.89
   2 ?   -3.1   0.1       4.1   3.5e+03     252     275 ..     689     712 ..     682     718 .. 0.74

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 1.5e-07
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49  51 ravLlaGpsgtGktalaiaiskelgedvpfvalsgsev 88 
                 ++vLl+Gp+gtGkt la a++ e g  vpf  +sgse+
  EEA20300.1 355 KGVLLVGPPGTGKTLLARAVAGEAG--VPFFYMSGSEF 390
                 89*********************98..*********85 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 4.1
                 XXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49 252 teiteklreeinkkvakyveegka 275
                   + +++++ei+  + + veeg++
  EEA20300.1 689 DKLSSETKQEIEAEIRRLVEEGRS 712
                 456778888888888888888865 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.8   6.9e-07   0.00059      24     126 ..     354     448 ..     331     460 .. 0.63

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 6.9e-07
      AAA_16  24 pelvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipysalaqalareellrqlldeaesaeleawrekleealaavpelagaea...srl 119
                 p  vll+G++G+GK+ l+r+++ ++      f++    ++      + +     + + +r+l ++a++++++      ++a++a ++ ++a a   + l
  EEA20300.1 354 PKGVLLVGPPGTGKTLLARAVAGEAGVP---FFYMSGSEF------DEVYVGVGA-KRVRDLFAQARAKAPAIIFIDELDAIGAKRNERDA-AyvkQTL 441
                 489*******************766655...433333333......224445534.67777777766666666666666666633333332.2365666 PP

      AAA_16 120 lellkrl 126
                 ++ll++l
  EEA20300.1 442 NQLLTEL 448
                 6666655 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       9.4     8e+03      60      97 ..     139     178 ..     119     179 .. 0.61
   2 !   14.7   0.2   3.4e-05     0.029       8      43 ..     357     383 ..     354     468 .. 0.62

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 9.4
      AAA_22  60 llralglelka...erlsseellealeqalraraviellii 97 
                 l +++  ++++   ++  s    ++++qal ++ + +++i+
  EEA20300.1 139 LSQNFLAQKERaanSNPGSANAQNTFYQALLRANM-PAIIV 178
                 44444444444444455666666777777777777.66665 PP

  == domain 2  score: 14.7 bits;  conditional E-value: 3.4e-05
      AAA_22   8 lvvtGesGtGKTtllrrlleqldeeakaeeerpevv 43 
                 ++++G++GtGKT+l+r ++ ++         +++++
  EEA20300.1 357 VLLVGPPGTGKTLLARAVAGEA---------GVPFF 383
                 589**************99887.........44433 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.0   0.0   1.1e-06   0.00092      34      96 ..     355     425 ..     319     437 .. 0.72
   2 ?   -3.7   0.0        10   8.5e+03      14      54 ..     489     532 ..     479     538 .. 0.61

  Alignments for each domain:
  == domain 1  score: 19.0 bits;  conditional E-value: 1.1e-06
      RuvB_N  34 dhvllyGpPGlGkttlakiiakelgvklkitsgPvle.........kagdlaalltnleekdvlfideihrl 96 
                   vll+GpPG Gkt la+ +a e gv +   sg   +         + +dl a   + ++  ++fide+  +
  EEA20300.1 355 KGVLLVGPPGTGKTLLARAVAGEAGVPFFYMSGSEFDevyvgvgakRVRDLFAQA-RAKAPAIIFIDELDAI 425
                 569************************9999998765111111111445555543.3455567888887665 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 10
      RuvB_N  14 kvkeklkifieaakkreeald...hvllyGpPGlGkttlakiia 54 
                 +v+ +++i+ +  k  +++ d    v+  G PG+  + l +++ 
  EEA20300.1 489 DVRGRMEILKHHMKGVQTSTDvdvAVIARGTPGFSGADLENLVN 532
                 55555555544444444333321257778999988777777665 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   1.6e-05     0.014       2      25 ..     357     382 ..     357     486 .. 0.73

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 1.6e-05
      AAA_33   2 vllvGlpGsGKstlaerllkklg..a 25 
                 vllvG+pG+GK+ la+ ++ + g  +
  EEA20300.1 357 VLLVGPPGTGKTLLARAVAGEAGvpF 382
                 799****************9998743 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   1.9e-05     0.016      14      80 ..     307     381 ..     298     476 .. 0.67

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 1.9e-05
      DUF815  14 galepveevdevklddLvgidkqkealve......nteqf..leglpannvLLwGarGtGKSslvkallneyaee 80 
                 ++ e+ ++ ++v+++d++g d+ k++l+e      n e+f  l g+  + vLL+G  GtGK  l +a+  e+   
  EEA20300.1 307 QTNEATPQQQKVRFSDVHGCDEAKDELQEvvefllNPERFstLGGKLPKGVLLVGPPGTGKTLLARAVAGEAGVP 381
                 4567788999***************998833333355566334589999******************99876554 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   0.0   2.3e-05      0.02      49      71 ..     356     378 ..     352     440 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 2.3e-05
   IstB_IS21  49 nivllGpsGvGKshlaialgvea 71 
                 +++l+Gp+G+GK+ la a++ ea
  EEA20300.1 356 GVLLVGPPGTGKTLLARAVAGEA 378
                 699***************98765 PP

>> AAA_2  AAA domain (Cdc48 subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   5.8e-05     0.049       6      91 ..     357     435 ..     354     458 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 5.8e-05
                 EEEE--TTSSHHHHHHHHHHHTT-....-EEEEEGGG-------THHHHHHHHHTT.T-HHHHTTSEEEEETGGG------------ CS
       AAA_2   6 illlgptgvGktelakalaellfvkkekkliradaselleeeevehlvsrligapp.gyvgaeegGivllDEidKihpkessgadvS 91 
                 +ll+gp g+Gkt+la+a+a    v    ++  +  se+ e   v   v    +    +  +a+   i+++DE+d i + +++++d  
  EEA20300.1 357 VLLVGPPGTGKTLLARAVAGEAGV----PFFYMSGSEFDE---VYVGVGAKRVRDLfAQARAKAPAIIFIDELDAIGA-KRNERDAA 435
                 6899******************98....9*9999999999...55555544444440344455556**********99.55555543 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.2   5.8e-05      0.05      25      43 ..     357     375 ..     351     378 .. 0.91

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 5.8e-05
  Mg_chelatase  25 lllvGppGsGKtmlakrlp 43 
                   +llvGppG+GKt+la++++
    EEA20300.1 357 VLLVGPPGTGKTLLARAVA 375
                   89*************9875 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.3    0.0007      0.59      27      54 ..     350     375 ..     334     397 .. 0.77
   2 ?    3.9   0.1     0.042        36     130     172 ..     402     444 ..     395     463 .. 0.71

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0007
      AAA_25  27 kgllpagelallaGapgtGKttlaldla 54 
                 +g lp+g  +ll+G+pgtGKt la  +a
  EEA20300.1 350 GGKLPKG--VLLVGPPGTGKTLLARAVA 375
                 5566655..689*********9986554 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.042
      AAA_25 130 vdaleaaieevegvrlvviDplsralgg.densnsdvgalveal 172
                 v++l a++++ + ++ + iD l+++ +  +e +++ v++ +++l
  EEA20300.1 402 VRDLFAQARA-KAPAIIFIDELDAIGAKrNERDAAYVKQTLNQL 444
                 6788899999.88***********99995666666665555544 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   0.00011     0.093       1     101 [.     357     462 ..     357     481 .. 0.54

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 0.00011
      AAA_18   1 IlltGtpGvGKttlakeLskrlgf..gvnlrdvakenglllevdpe.aldeskrldedkldklldaleenssaleegknlvidghlaeleseaakdikk 96 
                 +ll G+pG+GKt la++++ + g+   + +++ + e +   +     +l  + r++ +     +d+l+++ +++ e +  ++ + l++l+ e + + ++
  EEA20300.1 357 VLLVGPPGTGKTLLARAVAGEAGVpfFYMSGSEFDEVYVGVGAKRVrDLFAQARAKAPA-IIFIDELDAIGAKRNERDAAYVKQTLNQLLTELDGFSQT 454
                 799***************88877777444444444433333333332112222222222.222344444433555555556666666666665555555 PP

      AAA_18  97 ...vvLta 101
                    ++L a
  EEA20300.1 455 sgvIILAA 462
                 55555555 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.0    0.0018       1.5      21      37 ..     356     372 ..     332     386 .. 0.87
   2 ?    1.6   0.0      0.17   1.5e+02     119     158 ..     413     455 ..     399     471 .. 0.72

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0018
      ATPase  21 vvlitGepGtGKtifal 37 
                  vl++G pGtGKt++a 
  EEA20300.1 356 GVLLVGPPGTGKTLLAR 372
                 489***********986 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.17
      ATPase 119 kakrvviDsitgl...ayeekeavaReilrqlvrvlkklgvTa 158
                     + iD ++++    +e ++a ++++l ql+++l +  +T+
  EEA20300.1 413 APAIIFIDELDAIgakRNERDAAYVKQTLNQLLTELDGFSQTS 455
                 4466778888888621344455669************999997 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   0.1    0.0021       1.8       3      22 ..     357     376 ..     355     381 .. 0.88
   2 ?    2.0   0.0       0.2   1.7e+02      82     115 ..     414     447 ..     399     485 .. 0.77

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0021
                 EEEEC-TTTCHHHHHHHHHH CS
       NACHT   3 vilqGeaGsGKTtLlqklal 22 
                 v+l G++G GKT L++ +a 
  EEA20300.1 357 VLLVGPPGTGKTLLARAVAG 376
                 799*************9986 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.2
                 CEEEEEE-STT-SS-TCH.........HHHHHCT CS
       NACHT  82 rlLlilDglDelvtdlgqkekqpvrtlLselirk 115
                  + + +D lD + ++ ++ +++ v++ L++l+++
  EEA20300.1 414 PAIIFIDELDAIGAKRNERDAAYVKQTLNQLLTE 447
                 456779********99999999999999999998 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   0.00023      0.19       2      27 ..     357     383 ..     356     444 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00023
      AAA_28   2 ivitGgestGKTtlleaLa.argypvv 27 
                 + ++G+++tGKT l++a a + g+p +
  EEA20300.1 357 VLLVGPPGTGKTLLARAVAgEAGVPFF 383
                 689****************54588754 PP

>> AAA_17  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   0.00029      0.25       1      48 [.     360     408 ..     360     451 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00029
                 EE-TTSSHHHHHHHHHHHHTEEEEEH.HHHHHHHHHTTTSHSSHHHHCT CS
      AAA_17   1 lGgPGsGKgtqceklvekygfthlsa.Gdllreeakrgglakardemrk 48 
                 +G+PG GK+ +++ ++ + g++++ + G+ + e+    g+++ rd +++
  EEA20300.1 360 VGPPGTGKTLLARAVAGEAGVPFFYMsGSEFDEVYVGVGAKRVRDLFAQ 408
                 7*********************998867877777777777666666664 PP

>> SpoU_sub_bind  RNA 2'-O ribose methyltransferase substrate binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.078        67      14      50 ..     386     420 ..     383     423 .. 0.89
   2 ?    5.6   0.5     0.023        20      18      60 ..     714     749 ..     701     752 .. 0.77

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.078
  SpoU_sub_bind  14 sgrriekllvtegradkrleellklakkrgikvelvd 50 
                    sg+++++++v  g  +kr+++l+++a+++   ++++d
     EEA20300.1 386 SGSEFDEVYVGVG--AKRVRDLFAQARAKAPAIIFID 420
                    7889*********..99999********999888877 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.023
  SpoU_sub_bind  18 iekllvtegradkrleellklakkrgikvelvdkekLdklsgt 60 
                     +k+l ++        ++l+l++k+ i++e+ +ke+++k+ ++
     EEA20300.1 714 ATKILTEKR-------KELELLTKALIEYETLTKEEMEKVLRG 749
                    555555555.......999999999*************98776 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.1   0.00052      0.45      34      53 ..     355     374 ..     346     444 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00052
       AAA_7  34 kpvllvGptGtGKtviikdl 53 
                 k vllvGp GtGKt++++ +
  EEA20300.1 355 KGVLLVGPPGTGKTLLARAV 374
                 679************98875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (788 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       881  (0.0491383); expected 358.6 (0.02)
Passed bias filter:                      675  (0.0376485); expected 358.6 (0.02)
Passed Vit filter:                        96  (0.00535445); expected 17.9 (0.001)
Passed Fwd filter:                        21  (0.00117129); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              21  [number of targets reported over threshold]
# CPU time: 0.76u 0.31s 00:00:01.07 Elapsed: 00:00:00.44
# Mc/sec: 5399.47
//
Query:       EEA20301.1  [L=595]
Description: glycerol kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.8e-74  249.8   1.1    2.9e-74  249.1   1.1    1.4  1  FGGY_C          FGGY family of carbohydrate kinases, C-termin
    3.7e-61  206.8   0.0      5e-61  206.4   0.0    1.2  1  FGGY_N          FGGY family of carbohydrate kinases, N-termin
  ------ inclusion threshold ------
      0.044   13.3   1.0        4.3    6.7   0.0    2.3  2  BcrAD_BadFG     BadF/BadG/BcrA/BcrD ATPase family
       0.12   12.7   0.0       0.21   11.9   0.0    1.3  1  Pro-kuma_activ  Pro-kumamolisin, activation domain


Domain annotation for each model (and alignments):
>> FGGY_C  FGGY family of carbohydrate kinases, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  249.1   1.1   6.5e-78   2.9e-74       1     197 [.     302     493 ..     302     494 .. 0.99

  Alignments for each domain:
  == domain 1  score: 249.1 bits;  conditional E-value: 6.5e-78
      FGGY_C   1 akvslGTssflll.vgtkpvisehglltpva...gedgkpeyalegsiavagslvawlldnlglreeirdageveeslaelaaaeavadaggvvfvpaf 95 
                 ak+++GT++fll+ vg+kpvis+hgll++va   g+d+kp+yalegsiavags v +l++n g+   +rd+++v + +a     ++v+d+gg+vfv+af
  EEA20301.1 302 AKNTYGTGCFLLYnVGEKPVISKHGLLATVAfqlGADRKPVYALEGSIAVAGSGVSFLMNNMGF---FRDSKKV-SEVA-----ATVPDNGGCVFVTAF 391
                 79**************************************************************...*******.9999.....9************** PP

      FGGY_C  96 sglrapywdpdargtitglsssttlahiarAaleavalqlrailealekdsgkpldrlavdGGgskndllmqllAdilgvpVerpktaeatalGaAilA 194
                 sgl+apyw +da+gti+g++++t+ +hiarA+lea ++q++ail+a++kdsg++l+ lavdGG+s++d +mq +Adi+++pVerp ++e+talGaAi+A
  EEA20301.1 392 SGLFAPYWIDDAKGTIFGITQHTQRGHIARATLEAACFQTKAILDAMAKDSGHQLTDLAVDGGMSNSDICMQSQADIIQIPVERPSMHETTALGAAIAA 490
                 *************************************************************************************************** PP

      FGGY_C 195 ava 197
                 ++a
  EEA20301.1 491 GFA 493
                 *98 PP

>> FGGY_N  FGGY family of carbohydrate kinases, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  206.4   0.0   1.1e-64     5e-61       2     245 .]      39     293 ..      38     293 .. 0.96

  Alignments for each domain:
  == domain 1  score: 206.4 bits;  conditional E-value: 1.1e-64
                 EEEEEEESSEEEEEEEETTS-EEEEEEEE--EB-SSTT--EE-HHHHHHHHHHHHHHHHHHC...T.-GCCEEEEEEEE-SS-EEEEETTT.EESSEEE CS
      FGGY_N   2 ilglDcGttstkaivldekgkvvasaqaelelsspkegwaeqdpeeiwqalaeairkvleqa...gisekqikaIgisgqreglvllDknd.kpLynai 96 
                 i ++D+Gttst++iv+d +g  vas q e+ ++ ++ gw+eqdp+e+  ++ ++i+++++     g s+ +i+ Igi++qre++v++D ++ +p+ nai
  EEA20301.1  39 IGAIDQGTTSTRFIVFDGTGLPVASYQSEFRQIHAHSGWHEQDPRELVSTVEKCIEETMKTFlalGHSKTDIVTIGITNQRETTVVWDWETgEPIHNAI 137
                 679*********************************************************9888899*********************9999******* PP

                 -TT--TTHHHHHHHHHTTCHCCHHHHHSS-SSTTSHHHHHHHHHHHSCCHHCCHC....EEEEHHHHHHHHHCT.....--EEEHHHHCTTTSEETTTT CS
      FGGY_N  97 lwkdrrtaeiveklkeegnekklyektglvlstgftlsklkWlkenepevfekie....kflliddyLiwrLtg.....qfvtdvtnasesmlfnikkl 186
                  w d+rt+++v++l+ + ++++l ++ gl+lst+ + + l Wl+++ p+v ++ +    +f+++d++L + L g     +fvtdvtnas++m++n+++l
  EEA20301.1 138 AWPDTRTKGMVRELRSKEGADELDKICGLPLSTYPSSVTLMWLLRHRPSVKKAYDegrlAFGTVDSWLLYNLNGgvknkVFVTDVTNASRTMFMNLHEL 236
                 *****************************************************999******************************************* PP

                 EE-HHHHHHTT--GG..GS-EEE-TCCEEEEEECCCCCCTT.S-EEEEEEEEEHHHHHHHH CS
      FGGY_N 187 ewdeellailgipee..lLPklvesseiigelkpelaaklGlkegvpvvggggDqqaaalG 245
                 ++d++ll+++g++++   LPk+v+s+  ++  k      +    g+ + +++gDq+aa++G
  EEA20301.1 237 KYDDKLLNFFGLDQNklRLPKIVPSADPTAFGKLDGGPLA----GTTITSCLGDQSAALVG 293
                 ***************8899******998877666665555....699************98 PP

>> BcrAD_BadFG  BadF/BadG/BcrA/BcrD ATPase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   0.0   0.00097       4.3       3      35 ..      42      74 ..      40     124 .. 0.64
   2 ?    5.0   0.2    0.0033        15     184     267 .]     413     490 ..     409     490 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.00097
                 EEE-SSEEEEEEEETTTEEEEEEEE--TTS-HH CS
  BcrAD_BadFG  3 iDgGsTttkavlmdekgevlgrgitnsanlesv 35
                 iD G+T+t+++++d  g  ++ +++  ++++++
   EEA20301.1 42 IDQGTTSTRFIVFDGTGLPVASYQSEFRQIHAH 74
                 9*************9999877777777555543 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.0033
                  HHHTT--HHHHHHHHHHHHHHHHHHHHHTT---SS.EEEESGGGG-HHHHHHH.....HHHH-S-EE--GGGGGHHHHHHHHHH CS
  BcrAD_BadFG 184 alsggekaedIlaglhraialrvialisrsggvtdevtltGGvakneaavkelrklvkenygevkininpdsiytgalGAalfA 267
                  + ++g +a++ l+ ++ + +  + a+++ sg    ++ + GG++++   ++   + ++  + +      p    t alGAa+ A
   EEA20301.1 413 HTQRGHIARATLEAACFQTKAILDAMAKDSGHQLTDLAVDGGMSNSDICMQSQADIIQIPVER------PSMHETTALGAAIAA 490
                  678999*************************99999**********99998887777777766......777778899999766 PP

>> Pro-kuma_activ  Pro-kumamolisin, activation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   4.7e-05      0.21      26      80 ..     496     550 ..     473     564 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 4.7e-05
  Pro-kuma_activ  26 lekledflmdvsdpkspnygkhltaeevaelfapseeaidaVrnwLessgiaasr 80 
                     + + +d l+ ++  + + ++ +l+a+e a ++++  +a+d  r wL +s i  ++
      EEA20301.1 496 IWSTYDELRHMNRANRSVFKPYLSAQESALMYKQWTKAVDMTRGWLDASEIGRDE 550
                     5677889999999999**********************************98877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (595 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       411  (0.0229238); expected 358.6 (0.02)
Passed bias filter:                      382  (0.0213063); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.42
# Mc/sec: 4284.13
//
Query:       EEA20302.1  [L=311]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-43  148.6  10.1    2.4e-43  147.8  10.1    1.4  1  DUF3429   Protein of unknown function (DUF3429)


Domain annotation for each model (and alignments):
>> DUF3429  Protein of unknown function (DUF3429)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  147.8  10.1   1.4e-47   2.4e-43       1     143 [.     107     264 ..     107     265 .. 0.95

  Alignments for each domain:
  == domain 1  score: 147.8 bits;  conditional E-value: 1.4e-47
     DUF3429   1 vpklalvlGlaGliPfvalallt................laislllaeellstlaaaqlaYgavilSFlGGvhWgla.leeegaakakrtrlalsvvps 82 
                 vpk+al++GlaG++P+++++l t                +++s ++a+ ll+  +++q++YgavilSFlG++hWgl+ + ++g++    +r+a + +++
  EEA20302.1 107 VPKEALYFGLAGVVPYLVTSLNTcylawemnnnvvngsgFLLSEETASFLLQLTEPIQVGYGAVILSFLGAIHWGLEwAGYGGKR--GFRRYATGCIAP 203
                 79*************************************89999*********************************99999985..479********* PP

     DUF3429  83 llawlalllpseaalallilgflllllvDrraaragwlpswylklRfvltavvvlsllltl 143
                 ++aw++lllp e+al++ +l+f++l++ D+raa++g +p+wy+ +Rfvlt+vv++s+++tl
  EEA20302.1 204 AVAWPTLLLPVEYALITQFLAFTFLYYNDARAASRGFAPAWYGMYRFVLTFVVGASIVATL 264
                 **********7777777777***************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (311 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1033  (0.0576162); expected 358.6 (0.02)
Passed bias filter:                      526  (0.0293379); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 2214.98
//
Query:       EEA20303.1  [L=3163]
Description: vacuolar protein sorting-associated protein vps13 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   8.3e-100  333.6   0.0    4.2e-98  328.1   0.0    3.2  3  SHR-BD         SHR-binding domain of vacuolar-sorting associa
      4e-92  307.9  14.8    2.1e-89  299.0   1.0    5.7  5  VPS13_mid_rpt  Repeating coiled region of VPS13
    3.9e-81  272.3   0.7      6e-79  265.2   0.0    4.3  6  VPS13          Vacuolar sorting-associated protein 13, N-term
    1.2e-71  240.2   8.1    4.9e-69  231.7   0.2    2.9  3  VPS13_C        Vacuolar-sorting-associated 13 protein C-termi
    1.5e-40  137.9   0.0    6.3e-40  135.9   0.0    2.2  1  Chorein_N      N-terminal region of Chorein or VPS13
    8.6e-07   29.2   0.0      5e-06   26.8   0.0    2.3  2  ATG_C          Autophagy-related protein C terminal domain
  ------ inclusion threshold ------
      0.063   13.2   5.7        0.9    9.4   0.3    2.9  2  DUF896         Bacterial protein of unknown function (DUF896)


Domain annotation for each model (and alignments):
>> SHR-BD  SHR-binding domain of vacuolar-sorting associated protein 13
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0      0.62   1.6e+03     204     232 ..     539     565 ..     529     594 .. 0.73
   2 ?    1.1   0.0     0.079     2e+02       7     150 ..    1895    2047 ..    1893    2072 .. 0.61
   3 !  328.1   0.0  1.6e-101   4.2e-98       1     270 [.    2231    2510 ..    2231    2511 .. 0.98

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.62
      SHR-BD 204 ledatifikiedaeknewPfsirNeseve 232
                 ++++tif++i   ++   P +i+N s+ e
  EEA20303.1 539 TTEGTIFPQIVRVKDS--PGQIENVSSGE 565
                 6789********9999..******97533 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.079
      SHR-BD    7 apywllNkTglpLevrqednsneaagqleeeeearsltpllfSfddr......dtknraqlrignskwskpfsldaigetnevelrsaekesevy.i 96  
                  apy + N Tg +L+v  + +  e+ ++++ ++++++   +  +   r      ++ + + ++++ s + +   +  i+e +++   +++k++ ++ +
  EEA20303.1 1895 APYRIRNYTGFDLQVWADVEVGENGPTAKLSDGEEYPWRFEDATTMRenltpeGNAGLVGIKLEGSGFDSISRIPVIREGETLYNLKPKKDKVLHkL 1991
                  6888888888888888888877777777766433332222222222122222277777777777777777777777888888887777777767788 PP

      SHR-BD   97 GisveegrgkykltkiVtiaPRyilkNklsekleiaqrgs.....kkvielkpgelipl 150 
                   ++v+ g+++    k +t+ +  +l+N++++++e+   +       k+++++pg+  p 
  EEA20303.1 1992 LVEVKLGSDNV---KYITFRSPLLLENNTQIPVEMGIFSPedghlLKIEKIQPGDARPA 2047
                  88888888887...889999999999998888775433332133334456666666655 PP

  == domain 3  score: 328.1 bits;  conditional E-value: 1.6e-101
      SHR-BD    1 lkisIyapywllNkTglpLevrqednsneaagqleee....eearsltpllfSfddrdtknraqlrignskwskpfsldaigetnevelrsaekese 93  
                  +k+s+y+py++lN+Tgl++ev++++ +++a++++ +     + a  ++p+++S+ ++d+knr +++ig+skwskp+s+daig+t+ev++  +++++e
  EEA20303.1 2231 FKVSVYSPYLVLNQTGLSMEVQSKGFMQSARSSAGQGidadSAAGHAKPYMYSYPTDDQKNRSIIKIGDSKWSKPQSFDAIGSTFEVIVGARTSRAE 2327
                  589******************************99879886699**************************************************99* PP

      SHR-BD   94 vyiGisveegrgkykltkiVtiaPRyilkNklsekleiaqrgskkvielkpgeliplhwlrnkeekelvirlpesnsqwSggfnisdvgslyvklrr 190 
                  ++ G+sv+eg+gkyklt++Vti+PR+ilkNkl+e+l+++++g+++v ++k g+l+plh+lr++ ek+l++++p++n+qwS++fni+d+g ++vkl +
  EEA20303.1 2328 FHAGVSVSEGEGKYKLTRVVTITPRFILKNKLNEELQVREPGTSNVLTMKAGDLVPLHFLRQVPEKQLCLCFPGVNNQWSSPFNIADIGIMHVKLAK 2424
                  ************************************************************************************************* PP

      SHR-BD  191 qnseqvllkveiiledatifikiedaeknewPfsirNeseveilfyqrdpelnsd.......eskplkytlppksvmpYawDePtak 270 
                  ++++q+l+kvei++e+atifi+++ ++k+ wP+s+rNes+ e++fyq +p++++d        ++p++y+lpp+s+mpYawD+P+ak
  EEA20303.1 2425 ASQRQRLIKVEIVMENATIFIHLKMETKH-WPYSMRNESDMELIFYQSNPNVDEDeyddtnsGWRPIRYRLPPRSIMPYAWDYPAAK 2510
                  *****************************.********************************9*********************997 PP

>> VPS13_mid_rpt  Repeating coiled region of VPS13
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  299.0   1.0   8.1e-93   2.1e-89       2     235 .]     589     824 ..     588     824 .. 0.99
   2 ?    2.1   0.1     0.041   1.1e+02       9      58 ..    1005    1054 ..    1000    1075 .. 0.75
   3 ?    1.2   0.0     0.081   2.1e+02      11      85 ..    1164    1227 ..    1162    1269 .. 0.63
   4 !   10.1   0.1   0.00015      0.38     176     235 .]    1295    1353 ..    1271    1353 .. 0.80
   5 ?   -0.0   0.2      0.19   4.9e+02     158     224 ..    1618    1692 ..    1558    1701 .. 0.65

  Alignments for each domain:
  == domain 1  score: 299.0 bits;  conditional E-value: 8.1e-93
  VPS13_mid_rpt   2 etnPldekadqrlsiklrpleiiYdaetveevvkffkppksvlesvealssaasstleelkeqtragleyaleehktldlkidlqapliiiPesit 97 
                    e+nPl+++ad+++++kl+++e+iY++++v ev +ffkpp++++esv+al ++a++t++e+++qtragleyale h ++d + dlqapliiiPesit
     EEA20303.1 589 EQNPLESDADTAVKVKLKSIEVIYNPRFVVEVARFFKPPERHMESVGALLDSAGATVQEIRQQTRAGLEYALEAHRKVDTQFDLQAPLIIIPESIT 684
                    9*********************************************************************************************** PP

  VPS13_mid_rpt  98 eeessllvlDlGhlsveselvdksaikeikskskqqyseedleeleelmYDkfslklsdtqvllgdsgedwkeals.ed.ssklhilepinlkltl 191
                    ee   +l+lD+Gh+ v+selvd+ ++++++sk+k+qy+eed+++leel+YDkf +kl+++q+l+g+++e++k++l+ +d +++lhi+++in++++l
     EEA20303.1 685 EEGALCLILDAGHIRVNSELVDRGTMSDLQSKQKRQYNEEDYKQLEELLYDKFLIKLDSIQLLIGPNIEATKAQLTsDDpTKDLHIVDRINVDFVL 780
                    ****************************************************************************6446889************* PP

  VPS13_mid_rpt 192 eksivpkalnlpkfkvsgelpslevnlsdkkykslmelidtsiP 235
                    e +ivpk ++l++++vsg+lp+l++++sd+kyk+lm+lid +iP
     EEA20303.1 781 ELCIVPKTTTLTRTRVSGHLPELHASMSDSKYKNLMKLIDIAIP 824
                    ******************************************99 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.041
  VPS13_mid_rpt    9 kadqrlsiklrpleiiYdaetveevvkffkppksvlesvealssaasstl 58  
                      +d +l+i +++++ii+ ++t+ ++++f+    ++ e+ +a+ ++a st 
     EEA20303.1 1005 GVDMNLDIAVSTINIIVTRRTLLTLLDFVLLTFTNPEQPQAVDQSANSTA 1054
                     58999**********************96544444444444444444444 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.081
  VPS13_mid_rpt   11 dqrlsiklrpleiiYdaetveevvkffkppksvlesvealssaasstleelkeqtragleyaleehktldlkidl 85  
                     d+++ +++ +++i    e   ++v+f+ +  + +  ++a  +aa+s+ ++l+e+            +++ ++i +
     EEA20303.1 1164 DSEVFLRSGSIKIQLLEEPYRKIVNFLVKFGKMQAIFNAARQAAASQANQLQEN-----------ASRMRFDIIV 1227
                     666666666666666666666777776666666666666666666666666654...........4444444444 PP

  == domain 4  score: 10.1 bits;  conditional E-value: 0.00015
  VPS13_mid_rpt  176 ssklhilepinlkltleksivpkalnlpkfkvsgelpslevnlsdkkykslmelidtsiP 235 
                     +++l +++++nl++++     + ++  p ++v+g++  +++++s  ++k l+e++ + +P
     EEA20303.1 1295 HEQLEMIQKVNLDFSICYLEHQPDQPRPDIEVEGTMSPIKLRVSQPQLKFLLEIL-KTVP 1353
                     46789999999998886666666777788**************************.5566 PP

  == domain 5  score: -0.0 bits;  conditional E-value: 0.19
  VPS13_mid_rpt  158 qvllgdsgedwkeals...........edssklhilepinlkltleksivpkalnlpkfkvsgelpslevnlsdkkyk 224 
                     qvl+++++ ++ +  +           e +s+l+il+ ++l+l++++   +k   l ++   ++++ l ++ls + + 
     EEA20303.1 1618 QVLFSHQNVSTLQINKvgmflcrmdkfE-TSRLRILDDFTLELSVDSRAQDKGSALISID--VHVEPLVLRLSLRDIL 1692
                     5555555555554444555555554322.4779999999999999999998877665555..5555555555555544 PP

>> VPS13  Vacuolar sorting-associated protein 13, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  265.2   0.0   2.4e-82     6e-79       1     236 []     139     376 ..     139     376 .. 0.95
   2 ?    1.2   0.1       0.1   2.6e+02     117     169 ..     767     820 ..     709     830 .. 0.77
   3 ?   -2.4   0.0       1.3   3.3e+03     115     139 ..     933     957 ..     909     976 .. 0.66
   4 ?   -2.1   0.0       1.1   2.8e+03     134     175 ..    1154    1197 ..    1144    1215 .. 0.77
   5 ?   -2.5   0.0       1.4   3.5e+03     122     170 ..    1302    1351 ..    1266    1353 .. 0.79
   6 ?   -2.4   0.0       1.3   3.3e+03     127     182 ..    1656    1712 ..    1641    1722 .. 0.77

  Alignments for each domain:
  == domain 1  score: 265.2 bits;  conditional E-value: 2.4e-82
       VPS13   1 FlesLiakIldNlqvtiknvHiryeDslsvpgrpfalGitLesLsaqstdenwkptfikgeeseekivyKlvelesLavYwdsds..........sedk 89 
                 F++s+++ I+dNlq++iknvHiryeDs+ +pg+pfa+G+tL++Lsa+std++w ptfi++   ++++++Kl+ l  LavYw++d+             +
  EEA20303.1 139 FTQSFTTAIVDNLQISIKNVHIRYEDSIASPGHPFAVGMTLKELSAVSTDSEWHPTFIQS---TSGTTHKLAVLGALAVYWNTDTellgtgsgadF-GA 233
                 99*************************99999****************************...9*********************88888766541.45 PP

       VPS13  90 sledlsleeleeafessikeksekakrhqYiLkPvsgeaklklnkkgetdapklkldleldevgltLseeqyrdilklleslsrlerreeyrklrPkvs 188
                 + + ++++el ++++++i+ ++    + qYiL+Pvsg+a l+++k+g+ d+p++k +l ++e+g++L+++qyrd l+l++ ++++ r++ey+klrP++s
  EEA20303.1 234 EAQGIPHTELMAKLRDGIELDE----KNQYILRPVSGRAGLEMDKTGKLDRPRMKTRLLFNELGFVLDSDQYRDTLMLVDLFHYFLRHQEYKKLRPSSS 328
                 5678999***********7655....69*********************************************************************** PP

       VPS13 189 vkenpraWWkYaikavleeirekrrkwsweaiaerrdlrkrYvelykk 236
                 +ke+praW+++a +avl++i+e++r w+w++i+errd+r +Y+ l+kk
  EEA20303.1 329 PKEDPRAWFRFAGNAVLSKIHERNRVWTWDYIKERRDDRLAYIYLFKK 376
                 **********************************************96 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.1
       VPS13 117 hqYiLkPvsgeaklkln..kkgetdapklkldleldevgltLseeqyrdilklle 169
                    i+  +++++ l+l    k++t   + +++ +l e++ ++s+++y++++kl++
  EEA20303.1 767 DLHIVDRINVDFVLELCivPKTTTL-TRTRVSGHLPELHASMSDSKYKNLMKLID 820
                 5556666666666655532444443.899***********************997 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 1.3
       VPS13 115 krhqYiLkPvsgeaklklnkkgetd 139
                  + +Y L+P+++ a+l+l++ + +d
  EEA20303.1 933 FELDYYLRPFDMVAELTLKSLSVDD 957
                 358999******9999998544444 PP

  == domain 4  score: -2.1 bits;  conditional E-value: 1.1
       VPS13  134 kkgetdapklkldlel..devgltLseeqyrdilklleslsrle 175 
                   +++++ p ++ +++l   +++++L ee yr+i+++l ++  ++
  EEA20303.1 1154 DPDSAEYPGYDSEVFLrsGSIKIQLLEEPYRKIVNFLVKFGKMQ 1197
                  44445569999999994455**************9998887766 PP

  == domain 5  score: -2.5 bits;  conditional E-value: 1.4
       VPS13  122 kPvsgeaklklnkkgetd.apklkldleldevgltLseeqyrdilklles 170 
                  + v+ ++ + + ++++++ +p ++++  ++ ++l +s+ q++ +l++l++
  EEA20303.1 1302 QKVNLDFSICYLEHQPDQpRPDIEVEGTMSPIKLRVSQPQLKFLLEILKT 1351
                  55666666666555555557999999999************999999887 PP

  == domain 6  score: -2.4 bits;  conditional E-value: 1.3
       VPS13  127 eaklklnkkgetd.apklkldleldevgltLseeqyrdilklleslsrlerreeyrk 182 
                  +++l+++++++++ +  +++d++++ + l Ls + +  ++++++++s +++  e++k
  EEA20303.1 1656 TLELSVDSRAQDKgSALISIDVHVEPLVLRLSLRDILLATQIMNKVSEMRKPPEVEK 1712
                  445555544444436999*****************9999999999999988666655 PP

>> VPS13_C  Vacuolar-sorting-associated 13 protein C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.1       2.4   6.2e+03      70      95 ..     708     733 ..     697     734 .. 0.87
   2 !  231.7   0.2   1.9e-72   4.9e-69       1     177 [.    2760    2934 ..    2760    2935 .. 0.97
   3 !   12.6   0.7   3.5e-05     0.089     108     169 ..    2961    3023 ..    2957    3027 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 2.4
     VPS13_C  70 lslesliekikkhYsqqllkqlykil 95 
                  ++++l++k k+ Y+++ +kql  +l
  EEA20303.1 708 GTMSDLQSKQKRQYNEEDYKQLEELL 733
                 5788*****************98876 PP

  == domain 2  score: 231.7 bits;  conditional E-value: 1.9e-72
     VPS13_C    1 kiYfeklhlqPiklhlsfslsekknkeeslekeqsllslllllnslgvtltniddapikLnalelenvflslesliekikkhYsqqllkqlykilgs 97  
                  ++Yfe lhlqP++l++sf+++e+ n+e++  + +s+l+++  +n+++++++n++dap++Lnal+len+++s++ li+++ khY+q++l+q++ +lgs
  EEA20303.1 2760 DVYFELLHLQPMQLDISFMRTERVNAEDNI-QPSSPLMFF--VNVMTMSIGNVNDAPVRLNALILENARVSIPLLISNMRKHYTQEFLRQIHIVLGS 2853
                  58************************9854.569999999..******************************************************* PP

     VPS13_C   98 ldvlGNPvglfnnissGvkdlfyePiqglvkg.peefgeglakGaksLvkktvfGvadsvskitgsvskglaaltmDeeYq 177 
                  +d+lGNPvglfn++ssGv+d+fyeP+qglv++ p+++g g+akGa+s+vkk+vfG++ds++kitgs+skglaa+t+D+e+q
  EEA20303.1 2854 ADFLGNPVGLFNTVSSGVADIFYEPYQGLVTDrPQDLGYGIAKGASSFVKKSVFGFSDSMAKITGSMSKGLAAATLDKEFQ 2934
                  *******************************99***********************************************9 PP

  == domain 3  score: 12.6 bits;  conditional E-value: 3.5e-05
     VPS13_C  108 fnnissGvkdlfyePiqglvkg.peefgeglakGaksLvkktvfGvadsvskitgsvskglaa 169 
                   ++i sG++ l   P+qg+ kg    f++g+  G+   v+k   G++d +s++++ v ++ ++
  EEA20303.1 2961 ASSIVSGIEGLARHPLQGAEKGgFGGFMKGVGVGVLGVVTKPAIGAFDLASNLAEGVRNTTTV 3023
                  67899****************999*****************************9998887665 PP

>> Chorein_N  N-terminal region of Chorein or VPS13
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  135.9   0.0   2.5e-43   6.3e-40       1     115 [.       2     115 ..       2     116 .. 0.98

  Alignments for each domain:
  == domain 1  score: 135.9 bits;  conditional E-value: 2.5e-43
   Chorein_N   1 leslvskllnryLgeyvenldrdqlkvslwsGeveLenlkLkkealdklelPfevkegvigklrlkipwsnlkskpvvieiedvyllaeprseseeede 99 
                 le++v++llnr+Lg y++n+d +ql++++wsG+v+L++l+L++eald+l+lP++v+eg+ig+l+l+ipwsnl+ kpv++eiedv+lla p+ e+ ++d 
  EEA20303.1   2 LEGVVANLLNRFLGIYIKNFDGKQLNIGIWSGDVKLHDLELRREALDQLHLPLNVVEGHIGQLTLSIPWSNLRGKPVKVEIEDVFLLAAPKVET-DYDP 99 
                 799***************************************************************************************9988.99** PP

   Chorein_N 100 ekeekreqaakkkkLa 115
                 e+e kr++a k+ kL+
  EEA20303.1 100 EEEAKRAHAIKMDKLE 115
                 *************997 PP

>> ATG_C  Autophagy-related protein C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       2.3   5.9e+03       4      24 ..    2883    2903 ..    2874    2927 .. 0.81
   2 !   26.8   0.0     2e-09     5e-06       2      83 ..    2940    3021 ..    2939    3027 .. 0.96

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 2.3
       ATG_C    4 yasqPedlreGlqqAysslsk 24  
                  ++++P+dl  G++++ ss+ k
  EEA20303.1 2883 VTDRPQDLGYGIAKGASSFVK 2903
                  678999999999999888765 PP

  == domain 2  score: 26.8 bits;  conditional E-value: 2e-09
       ATG_C    2 slyasqPedlreGlqqAysslskglksaaqtilavpsevaeskgakgavkavvravPvavlrPligateavsktlqGvrnql 83  
                  s+  ++P+    G++++ + + + + s  + + + p + ae++g +g++k+v   v  +v +P+iga + +s++  Gvrn+ 
  EEA20303.1 2940 SKARNRPKHALYGVTSGGNAFASSIVSGIEGLARHPLQGAEKGGFGGFMKGVGVGVLGVVTKPAIGAFDLASNLAEGVRNTT 3021
                  678899**************************************************************************86 PP

>> DUF896  Bacterial protein of unknown function (DUF896)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.3   0.00035       0.9      13      53 ..     123     163 ..     117     166 .. 0.90
   2 ?    4.9   0.8    0.0094        24       9      34 ..     374     399 ..     366     424 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00035
      DUF896  13 kktegLTeeEkeeqkkLRkeYlkafraslksqlenvkvvDe 53 
                   +eg+T+eE++  +   + + +a+  +l+  ++nv +  e
  EEA20303.1 123 RNAEGMTQEEQKRNQSFTQSFTTAIVDNLQISIKNVHIRYE 163
                 5689********************************99665 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.0094
      DUF896   9 LakkkktegLTeeEkeeqkkLRkeYl 34 
                 + kkk++e LT+++++e  +L ++Y 
  EEA20303.1 374 FKKKKREEALTADQNSEMGELERKYT 399
                 5689999*****************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (3163 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       690  (0.0384851); expected 358.6 (0.02)
Passed bias filter:                      458  (0.0255452); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 1.34u 0.29s 00:00:01.63 Elapsed: 00:00:00.48
# Mc/sec: 19665.27
//
Query:       EEA20304.1  [L=320]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.8e-17   62.8  33.5    5.7e-05   23.4   3.3    4.5  4  zf-C2H2      Zinc finger, C2H2 type
    6.5e-15   54.8  28.3    3.9e-06   27.1   1.0    5.2  6  zf-H2C2_2    Zinc-finger double domain
    1.9e-05   25.1  36.8      0.064   14.1   2.7    4.7  5  zf-C2H2_4    C2H2-type zinc finger
  ------ inclusion threshold ------
      0.016   15.5  11.1      0.055   13.8   5.6    3.1  2  zf-C2H2_8    C2H2-type zinc ribbon
      0.019   15.6  12.1       0.76   10.5   0.2    4.2  4  FOXP-CC      FOXP coiled-coil domain
       0.71    9.5   4.2        4.1    7.1   0.2    2.9  3  zf-tcix      Putative treble-clef, zinc-finger, Zn-binding
       0.74   10.2   7.5         36    4.8   0.0    4.2  4  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
          2    8.3  11.8        2.3    8.1  11.8    1.1  1  TFIIA        Transcription factor IIA, alpha/beta subunit
        2.3    8.7  13.8         13    6.3   0.5    4.5  4  zf-met       Zinc-finger of C2H2 type
        5.5    6.9  15.0       0.78    9.6   0.5    4.1  4  zf-CGNR      CGNR zinc finger


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.4   3.3   3.2e-08   5.7e-05       1      23 []       9      33 ..       9      33 .. 0.95
   2 !   18.3   1.9   1.3e-06    0.0023       1      23 []      39      63 ..      39      63 .. 0.95
   3 !   20.9   2.5   1.8e-07   0.00033       1      23 []      69      93 ..      69      93 .. 0.96
   4 !   17.9   2.9   1.7e-06    0.0031       1      23 []      99     124 ..      99     124 .. 0.93

  Alignments for each domain:
  == domain 1  score: 23.4 bits;  conditional E-value: 3.2e-08
                EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCp..dCgksFkrksnLkrHirtH 23
                + C+   CgksF+rks+L+rH+r+H
  EEA20304.1  9 FNCSweRCGKSFNRKSDLCRHYRIH 33
                7899999*****************9 PP

  == domain 2  score: 18.3 bits;  conditional E-value: 1.3e-06
                EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCp..dCgksFkrksnLkrHirtH 23
                y C+   C+ksF ++s L++H rtH
  EEA20304.1 39 YHCTvpSCNKSFIQRSALTVHSRTH 63
                7899999*****************9 PP

  == domain 3  score: 20.9 bits;  conditional E-value: 1.8e-07
                EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCp..dCgksFkrksnLkrHirtH 23
                ++C+  dC k F+++s+L rH+r+H
  EEA20304.1 69 HVCDheDCRKAFSDSSSLARHRRIH 93
                68999*******************9 PP

  == domain 4  score: 17.9 bits;  conditional E-value: 1.7e-06
                 EEET..TTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirt.H 23 
                 y C+   C++sF+rk  L++H+++ H
  EEA20304.1  99 YICSepACDRSFCRKTTLTKHQSRtH 124
                 7788889****************999 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.17     3e+02      15      25 ..       9      21 ..       4      22 .. 0.80
   2 !   22.4   2.9   6.3e-08   0.00011       4      24 ..      28      50 ..      25      52 .. 0.93
   3 !   27.1   1.0   2.2e-09   3.9e-06       1      25 [.      55      81 ..      55      82 .. 0.94
   4 !   20.0   0.7   3.6e-07   0.00065       1      24 [.      85     115 ..      85     117 .. 0.75
   5 ?   -1.7   0.1       2.8     5e+03       2      10 ..     116     125 ..     115     127 .. 0.70
   6 ?   -2.7   0.1       5.4   9.7e+03       8      14 ..     168     174 ..     167     176 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.17
   zf-H2C2_2 15 yeCp..lCdkaFk 25
                ++C+   C+k+F+
  EEA20304.1  9 FNCSweRCGKSFN 21
                8899977*****8 PP

  == domain 2  score: 22.4 bits;  conditional E-value: 6.3e-08
   zf-H2C2_2  4 rHirkHtgekpyeCp..lCdkaF 24
                rH r Ht+e+py+C   +C+k+F
  EEA20304.1 28 RHYRIHTNERPYHCTvpSCNKSF 50
                9**************99*****9 PP

  == domain 3  score: 27.1 bits;  conditional E-value: 2.2e-09
   zf-H2C2_2  1 nLrrHirkHtgekpyeCp..lCdkaFk 25
                +L+ H r+Htgekp+ C+   C+kaF+
  EEA20304.1 55 ALTVHSRTHTGEKPHVCDheDCRKAFS 81
                6899***************99*****6 PP

  == domain 4  score: 20.0 bits;  conditional E-value: 3.6e-07
   zf-H2C2_2   1 nLrrHirkHtgekpy.....eCp..lCdkaF 24 
                 +L rH r Htg +py      C+  +C+k++
  EEA20304.1  85 SLARHRRIHTGRRPYicsepACDrsFCRKTT 115
                 589************6666666666666665 PP

  == domain 5  score: -1.7 bits;  conditional E-value: 2.8
   zf-H2C2_2   2 LrrHi.rkHt 10 
                 L++H+ r+H 
  EEA20304.1 116 LTKHQsRTHQ 125
                 8899735685 PP

  == domain 6  score: -2.7 bits;  conditional E-value: 5.4
   zf-H2C2_2   8 kHtgekp 14 
                  H g++p
  EEA20304.1 168 YHNGPTP 174
                 69**998 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.1   2.7   3.5e-05     0.064       1      23 [.       9      33 ..       9      34 .. 0.92
   2 !   11.1   1.4   0.00033       0.6       1      23 [.      39      63 ..      39      64 .. 0.93
   3 !   12.6   1.8   0.00011      0.19       2      23 ..      70      93 ..      69      94 .. 0.92
   4 !   10.3   2.2   0.00061       1.1       1      24 []      99     124 ..      99     124 .. 0.90
   5 ?   -3.4   0.4        10   1.8e+04      17      21 ..     252     256 ..     248     257 .. 0.68

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 3.5e-05
   zf-C2H2_4  1 fkCpi..CgksFsskkaLlrHlkth 23
                f C++  CgksF++k++L+rH + h
  EEA20304.1  9 FNCSWerCGKSFNRKSDLCRHYRIH 33
                7799999***************998 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00033
   zf-C2H2_4  1 fkCpi..CgksFsskkaLlrHlkth 23
                + C++  C+ksF  ++aL  H +th
  EEA20304.1 39 YHCTVpsCNKSFIQRSALTVHSRTH 63
                6788888*****************9 PP

  == domain 3  score: 12.6 bits;  conditional E-value: 0.00011
   zf-C2H2_4  2 kCpi..CgksFsskkaLlrHlkth 23
                 C++  C+k Fs++++L rH + h
  EEA20304.1 70 VCDHedCRKAFSDSSSLARHRRIH 93
                799999**************9998 PP

  == domain 4  score: 10.3 bits;  conditional E-value: 0.00061
   zf-C2H2_4   1 fkCpi..CgksFsskkaLlrHlkthH 24 
                 ++C+   C++sF++k++L +H  + H
  EEA20304.1  99 YICSEpaCDRSFCRKTTLTKHQSRTH 124
                 7899999**************98877 PP

  == domain 5  score: -3.4 bits;  conditional E-value: 10
   zf-C2H2_4  17 lrHlk 21 
                 ++H++
  EEA20304.1 252 QHHMA 256
                 67885 PP

>> zf-C2H2_8  C2H2-type zinc ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   5.6   3.1e-05     0.055       2      88 ..      11      92 ..      10      97 .. 0.85
   2 ?    5.2   2.1     0.015        26       2      61 ..      71     124 ..      68     134 .. 0.74

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 3.1e-05
   zf-C2H2_8  2 cssygcrlafpnvrelaqhlrvhlsptqslegklfrcstascaetfpsmqelvahtklhykpn.ryfkcencllrfrthrslfkhlhv 88
                cs   c  +f    +l +h+r h +       + ++c+ +sc ++f     l  h++ h   +      e+c   f    sl +h  +
  EEA20304.1 11 CSWERCGKSFNRKSDLCRHYRIHTN------ERPYHCTVPSCNKSFIQRSALTVHSRTHTGEKpHVCDHEDCRKAFSDSSSLARHRRI 92
                9999999*************99975......5789************************754413457799*****999999999765 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.015
   zf-C2H2_8   2 cssygcrlafpnvrelaqhlrvhlsptqslegklfrcstascaetfpsmqelvahtklhy 61 
                 c    cr af ++  la+h r h         + + cs ++c  +f     l  h    +
  EEA20304.1  71 CDHEDCRKAFSDSSSLARHRRIHTG------RRPYICSEPACDRSFCRKTTLTKHQSRTH 124
                 6677788888888888888777643......24577899999999888888888865554 PP

>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.6     0.021        37       6      27 ..      10      31 ..       7      39 .. 0.89
   2 ?    2.3   0.1      0.15   2.6e+02       6      28 ..      40      62 ..      37      69 .. 0.86
   3 ?    3.3   0.1     0.071   1.3e+02       6      26 ..      70      90 ..      67      95 .. 0.89
   4 ?   10.5   0.2   0.00042      0.76       6      36 ..     100     130 ..      98     135 .. 0.92

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.021
     FOXP-CC  6 vCkWPgCekvledveeflkhln 27
                 C W  C k ++  +++ +h +
  EEA20304.1 10 NCSWERCGKSFNRKSDLCRHYR 31
                5*******************75 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.15
     FOXP-CC  6 vCkWPgCekvledveeflkhlns 28
                +C  P C+k + + ++++ h ++
  EEA20304.1 40 HCTVPSCNKSFIQRSALTVHSRT 62
                6999***********99999765 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.071
     FOXP-CC  6 vCkWPgCekvledveeflkhl 26
                vC+  +C k+++d++++ +h 
  EEA20304.1 70 VCDHEDCRKAFSDSSSLARHR 90
                79999**************95 PP

  == domain 4  score: 10.5 bits;  conditional E-value: 0.00042
     FOXP-CC   6 vCkWPgCekvledveeflkhlnseHalddks 36 
                 +C  P C++ +   ++++kh +++H+++ ++
  EEA20304.1 100 ICSEPACDRSFCRKTTLTKHQSRTHQPGGNT 130
                 5999**********************98765 PP

>> zf-tcix  Putative treble-clef, zinc-finger, Zn-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.2    0.0023       4.1      21      40 ..       5      24 ..       2      26 .. 0.91
   2 ?   -1.9   0.0       1.5   2.7e+03      21      39 ..      65      83 ..      62      85 .. 0.75
   3 ?    2.9   0.2     0.046        83      20      36 ..      94     110 ..      92     115 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0023
     zf-tcix 21 GtRglsCkNkaCdqvfkkkd 40
                G+Rg+ C+ + C   f+ k+
  EEA20304.1  5 GSRGFNCSWERCGKSFNRKS 24
                9***************9986 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 1.5
     zf-tcix 21 GtRglsCkNkaCdqvfkkk 39
                G +  +C  ++C   f ++
  EEA20304.1 65 GEKPHVCDHEDCRKAFSDS 83
                6677789999999988765 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.046
     zf-tcix  20 NGtRglsCkNkaCdqvf 36 
                  G R  +C+ +aCd  f
  EEA20304.1  94 TGRRPYICSEPACDRSF 110
                 59999********9887 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.3      0.55   9.8e+02       7      21 ..      16      30 ..      16      31 .. 0.86
   2 ?    4.0   0.1     0.035        63       7      20 ..      46      59 ..      44      69 .. 0.84
   3 ?    4.8   0.0      0.02        36       7      21 ..      76      90 ..      74      91 .. 0.91
   4 ?    2.3   0.1      0.12   2.1e+02       6      21 ..     105     120 ..     104     121 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.55
                 TTBBBSSHHHHHCCT CS
  zf-C2H2_jaz  7 CdKyFksenaldnHl 21
                 C K F+  ++l  H+
   EEA20304.1 16 CGKSFNRKSDLCRHY 30
                 99****999998887 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.035
                 TTBBBSSHHHHHCC CS
  zf-C2H2_jaz  7 CdKyFksenaldnH 20
                 C+K F+  +al  H
   EEA20304.1 46 CNKSFIQRSALTVH 59
                 ******99999999 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.02
                 TTBBBSSHHHHHCCT CS
  zf-C2H2_jaz  7 CdKyFksenaldnHl 21
                 C K F+++++l  H 
   EEA20304.1 76 CRKAFSDSSSLARHR 90
                 *************97 PP

  == domain 4  score: 2.3 bits;  conditional E-value: 0.12
                  TTTBBBSSHHHHHCCT CS
  zf-C2H2_jaz   6 lCdKyFksenaldnHl 21 
                  +Cd+ F    +l +H+
   EEA20304.1 105 ACDRSFCRKTTLTKHQ 120
                  8*****9999999997 PP

>> TFIIA  Transcription factor IIA, alpha/beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1  11.8    0.0013       2.3     100     220 ..     121     254 ..      54     288 .. 0.45

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0013
       TFIIA 100 svqsltanssaataatfslpakleppvqipagvtlqtasg....qlykvnv.........qasgaqqiaaqplqqvvqqsqgsaaqssvaalqaqsqqa 185
                 s ++++ ++++ ++++  +p +++++  +++ +  +t+++    q y  n          q+++ +  ++qp++ v   +q ++a   ++++++q  + 
  EEA20304.1 121 SRTHQPGGNTRPSSEEAPTPESMTYQTPVITTMAPNTTQYiiaqQPYYHNGptpttadfyQTPQPAIHFTQPQAMVP--QQIPTAGLPTPPFEPQ--HY 215
                 22222212222233333333333332222222222222223323444333322222222233333333333333332..2344444444444443..33 PP

       TFIIA 186 qalaepqqqlekq.....qqq.qqqqqqqqqqqqvqqqqqe 220
                 ++++++qqq   +     +q+ +q q q   +  v q+q +
  EEA20304.1 216 AQIMQQQQQP--RydptpHQTyIQPQYQSPTPPFVAQHQHH 254
                 3333333331..12234433312222222222222222221 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.4     0.047        83       6      22 ..      16      32 ..      14      35 .. 0.86
   2 ?    3.2   0.2     0.068   1.2e+02       6      25 .]      46      63 ..      44      63 .. 0.86
   3 ?    2.4   0.1      0.12   2.2e+02       6      20 ..      76      90 ..      74      94 .. 0.87
   4 ?    6.3   0.5    0.0072        13       5      25 .]     105     124 ..     104     124 .. 0.90

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.047
      zf-met  6 CnvtfnsesqlksHlqG 22
                C ++fn +s+l  H++ 
  EEA20304.1 16 CGKSFNRKSDLCRHYRI 32
                **********9999986 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.068
      zf-met  6 CnvtfnsesqlksHlqGKkH 25
                Cn++f  +s+l  H  +++H
  EEA20304.1 46 CNKSFIQRSALTVH--SRTH 63
                ******99999888..7766 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.12
      zf-met  6 CnvtfnsesqlksHl 20
                C + f++ s+l  H 
  EEA20304.1 76 CRKAFSDSSSLARHR 90
                ************995 PP

  == domain 4  score: 6.3 bits;  conditional E-value: 0.0072
      zf-met   5 lCnvtfnsesqlksHlqGKkH 25 
                 +C+++f+ +++l  H q+++H
  EEA20304.1 105 ACDRSFCRKTTLTKH-QSRTH 124
                 7**************.77777 PP

>> zf-CGNR  CGNR zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.3      0.23   4.1e+02      26      33 ..      11      18 ..       2      26 .. 0.74
   2 ?    1.6   0.1      0.14   2.5e+02       4      18 ..      40      54 ..      37      57 .. 0.89
   3 ?    9.6   0.5   0.00043      0.78       3      22 ..      69      88 ..      68      92 .. 0.84
   4 ?    2.4   0.5     0.083   1.5e+02       4      18 ..     100     114 ..      97     123 .. 0.83

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.23
                SSHH.HHH CS
     zf-CGNR 26 CsmraCGn 33
                Cs ++CG+
  EEA20304.1 11 CSWERCGK 18
                99999997 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.14
                E--STT---EEE--S CS
     zf-CGNR  4 aCaapdCrwvfvDtS 18
                +C  p C+  f+ +S
  EEA20304.1 40 HCTVPSCNKSFIQRS 54
                699********9998 PP

  == domain 3  score: 9.6 bits;  conditional E-value: 0.00043
                EE--STT---EEE--SSS-- CS
     zf-CGNR  3 kaCaapdCrwvfvDtSrngs 22
                ++C+++dCr +f D S   +
  EEA20304.1 69 HVCDHEDCRKAFSDSSSLAR 88
                58************997554 PP

  == domain 4  score: 2.4 bits;  conditional E-value: 0.083
                 E--STT---EEE--S CS
     zf-CGNR   4 aCaapdCrwvfvDtS 18 
                  C++p C++ f  ++
  EEA20304.1 100 ICSEPACDRSFCRKT 114
                 6********998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (320 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       637  (0.035529); expected 358.6 (0.02)
Passed bias filter:                      293  (0.0163422); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.50u 0.24s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2212.98
//
Query:       EEA20305.1  [L=284]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    9.7e-18   63.6  33.5    4.8e-05   23.6   3.3    4.5  4  zf-C2H2      Zinc finger, C2H2 type
    1.1e-15   57.2  26.9    3.3e-06   27.3   1.0    5.3  6  zf-H2C2_2    Zinc-finger double domain
      1e-05   25.9  36.8      0.054   14.3   2.7    4.7  5  zf-C2H2_4    C2H2-type zinc finger
     0.0073   16.6  10.6       0.03   14.6   5.1    3.1  2  zf-C2H2_8    C2H2-type zinc ribbon
     0.0099   16.5  12.1       0.64   10.7   0.2    4.3  4  FOXP-CC      FOXP coiled-coil domain
  ------ inclusion threshold ------
       0.42   11.0   7.5         31    5.0   0.0    4.2  4  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
       0.49   10.1   4.2        3.5    7.3   0.2    2.9  3  zf-tcix      Putative treble-clef, zinc-finger, Zn-binding
        1.3    9.5  13.8         11    6.5   0.5    4.5  4  zf-met       Zinc-finger of C2H2 type
        4.1    7.3  12.9        4.5    7.2  12.9    1.1  1  TFIIA        Transcription factor IIA, alpha/beta subunit


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.6   3.3   2.4e-08   4.8e-05       1      23 []       9      33 ..       9      33 .. 0.95
   2 !   18.5   1.9     1e-06     0.002       1      23 []      39      63 ..      39      63 .. 0.95
   3 !   21.2   2.5   1.4e-07   0.00028       1      23 []      69      93 ..      69      93 .. 0.96
   4 !   18.1   2.9   1.3e-06    0.0027       1      23 []      99     124 ..      99     124 .. 0.93

  Alignments for each domain:
  == domain 1  score: 23.6 bits;  conditional E-value: 2.4e-08
                EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCp..dCgksFkrksnLkrHirtH 23
                + C+   CgksF+rks+L+rH+r+H
  EEA20305.1  9 FNCSweRCGKSFNRKSDLCRHYRIH 33
                7899999*****************9 PP

  == domain 2  score: 18.5 bits;  conditional E-value: 1e-06
                EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCp..dCgksFkrksnLkrHirtH 23
                y C+   C+ksF ++s L++H rtH
  EEA20305.1 39 YHCTvpSCNKSFIQRSALTVHSRTH 63
                7899999*****************9 PP

  == domain 3  score: 21.2 bits;  conditional E-value: 1.4e-07
                EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCp..dCgksFkrksnLkrHirtH 23
                ++C+  dC k F+++s+L rH+r+H
  EEA20305.1 69 HVCDheDCRKAFSDSSSLARHRRIH 93
                68999*******************9 PP

  == domain 4  score: 18.1 bits;  conditional E-value: 1.3e-06
                 EEET..TTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirt.H 23 
                 y C+   C++sF+rk  L++H+++ H
  EEA20305.1  99 YICSepACDRSFCRKTTLTKHQSRtH 124
                 7788889****************999 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.0      0.13   2.6e+02      15      25 ..       9      21 ..       4      22 .. 0.80
   2 !   22.6   2.9   4.9e-08   9.7e-05       4      24 ..      28      50 ..      25      52 .. 0.93
   3 !   27.3   1.0   1.7e-09   3.3e-06       1      25 [.      55      81 ..      55      82 .. 0.94
   4 !   20.1   0.8     3e-07   0.00059       1      24 [.      85     115 ..      85     117 .. 0.75
   5 ?   -1.5   0.1       2.2   4.3e+03       2      10 ..     116     125 ..     115     127 .. 0.71
   6 ?   -2.3   0.0       3.8   7.5e+03       8      14 ..     168     174 ..     167     179 .. 0.86

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.13
   zf-H2C2_2 15 yeCp..lCdkaFk 25
                ++C+   C+k+F+
  EEA20305.1  9 FNCSweRCGKSFN 21
                8899977*****8 PP

  == domain 2  score: 22.6 bits;  conditional E-value: 4.9e-08
   zf-H2C2_2  4 rHirkHtgekpyeCp..lCdkaF 24
                rH r Ht+e+py+C   +C+k+F
  EEA20305.1 28 RHYRIHTNERPYHCTvpSCNKSF 50
                9**************99*****9 PP

  == domain 3  score: 27.3 bits;  conditional E-value: 1.7e-09
   zf-H2C2_2  1 nLrrHirkHtgekpyeCp..lCdkaFk 25
                +L+ H r+Htgekp+ C+   C+kaF+
  EEA20305.1 55 ALTVHSRTHTGEKPHVCDheDCRKAFS 81
                6899***************99*****6 PP

  == domain 4  score: 20.1 bits;  conditional E-value: 3e-07
   zf-H2C2_2   1 nLrrHirkHtgekpy.....eCp..lCdkaF 24 
                 +L rH r Htg +py      C+  +C+k++
  EEA20305.1  85 SLARHRRIHTGRRPYicsepACDrsFCRKTT 115
                 589************6666666666666665 PP

  == domain 5  score: -1.5 bits;  conditional E-value: 2.2
   zf-H2C2_2   2 LrrHi.rkHt 10 
                 L++H+ r+H 
  EEA20305.1 116 LTKHQsRTHQ 125
                 8899735685 PP

  == domain 6  score: -2.3 bits;  conditional E-value: 3.8
   zf-H2C2_2   8 kHtgekp 14 
                  H g++p
  EEA20305.1 168 YHNGPTP 174
                 699*998 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   2.7   2.7e-05     0.054       1      23 [.       9      33 ..       9      34 .. 0.92
   2 !   11.3   1.4   0.00026      0.51       1      23 [.      39      63 ..      39      64 .. 0.93
   3 !   12.8   1.8   8.3e-05      0.17       2      23 ..      70      93 ..      69      94 .. 0.92
   4 !   10.5   2.2   0.00047      0.94       1      24 []      99     124 ..      99     124 .. 0.90
   5 ?   -3.2   0.4         9   1.8e+04      17      21 ..     252     256 ..     248     257 .. 0.68

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2.7e-05
   zf-C2H2_4  1 fkCpi..CgksFsskkaLlrHlkth 23
                f C++  CgksF++k++L+rH + h
  EEA20305.1  9 FNCSWerCGKSFNRKSDLCRHYRIH 33
                7799999***************998 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00026
   zf-C2H2_4  1 fkCpi..CgksFsskkaLlrHlkth 23
                + C++  C+ksF  ++aL  H +th
  EEA20305.1 39 YHCTVpsCNKSFIQRSALTVHSRTH 63
                6788888*****************9 PP

  == domain 3  score: 12.8 bits;  conditional E-value: 8.3e-05
   zf-C2H2_4  2 kCpi..CgksFsskkaLlrHlkth 23
                 C++  C+k Fs++++L rH + h
  EEA20305.1 70 VCDHedCRKAFSDSSSLARHRRIH 93
                799999**************9998 PP

  == domain 4  score: 10.5 bits;  conditional E-value: 0.00047
   zf-C2H2_4   1 fkCpi..CgksFsskkaLlrHlkthH 24 
                 ++C+   C++sF++k++L +H  + H
  EEA20305.1  99 YICSEpaCDRSFCRKTTLTKHQSRTH 124
                 7899999**************98877 PP

  == domain 5  score: -3.2 bits;  conditional E-value: 9
   zf-C2H2_4  17 lrHlk 21 
                 ++H++
  EEA20305.1 252 QHHMA 256
                 67885 PP

>> zf-C2H2_8  C2H2-type zinc ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   5.1   1.5e-05      0.03       2      88 ..      11      92 ..      10      97 .. 0.85
   2 !    5.8   1.6    0.0085        17       2      61 ..      71     124 ..      70     132 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 1.5e-05
   zf-C2H2_8  2 cssygcrlafpnvrelaqhlrvhlsptqslegklfrcstascaetfpsmqelvahtklhykpn.ryfkcencllrfrthrslfkhlhv 88
                cs   c  +f    +l +h+r h +       + ++c+ +sc ++f     l  h++ h   +      e+c   f    sl +h  +
  EEA20305.1 11 CSWERCGKSFNRKSDLCRHYRIHTN------ERPYHCTVPSCNKSFIQRSALTVHSRTHTGEKpHVCDHEDCRKAFSDSSSLARHRRI 92
                999999**************99975......5789************************754413457799*****999999999765 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0085
   zf-C2H2_8   2 cssygcrlafpnvrelaqhlrvhlsptqslegklfrcstascaetfpsmqelvahtklhy 61 
                 c    cr af ++  la+h r h         + + cs ++c  +f     l  h    +
  EEA20305.1  71 CDHEDCRKAFSDSSSLARHRRIHTG------RRPYICSEPACDRSFCRKTTLTKHQSRTH 124
                 6677888888888888888877743......24578999999999998888888865554 PP

>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.6     0.016        32       6      27 ..      10      31 ..       7      39 .. 0.89
   2 ?    2.5   0.1      0.11   2.2e+02       6      28 ..      40      62 ..      37      69 .. 0.86
   3 ?    3.5   0.1     0.055   1.1e+02       6      26 ..      70      90 ..      67      95 .. 0.89
   4 !   10.7   0.2   0.00032      0.64       6      36 ..     100     130 ..      98     135 .. 0.92

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.016
     FOXP-CC  6 vCkWPgCekvledveeflkhln 27
                 C W  C k ++  +++ +h +
  EEA20305.1 10 NCSWERCGKSFNRKSDLCRHYR 31
                5*******************75 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.11
     FOXP-CC  6 vCkWPgCekvledveeflkhlns 28
                +C  P C+k + + ++++ h ++
  EEA20305.1 40 HCTVPSCNKSFIQRSALTVHSRT 62
                6999***********99999765 PP

  == domain 3  score: 3.5 bits;  conditional E-value: 0.055
     FOXP-CC  6 vCkWPgCekvledveeflkhl 26
                vC+  +C k+++d++++ +h 
  EEA20305.1 70 VCDHEDCRKAFSDSSSLARHR 90
                79999**************95 PP

  == domain 4  score: 10.7 bits;  conditional E-value: 0.00032
     FOXP-CC   6 vCkWPgCekvledveeflkhlnseHalddks 36 
                 +C  P C++ +   ++++kh +++H+++ ++
  EEA20305.1 100 ICSEPACDRSFCRKTTLTKHQSRTHQPGGNT 130
                 5999**********************98765 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.3      0.43   8.5e+02       7      21 ..      16      30 ..      16      31 .. 0.86
   2 ?    4.2   0.1     0.027        54       7      20 ..      46      59 ..      44      69 .. 0.84
   3 ?    5.0   0.0     0.015        31       7      21 ..      76      90 ..      74      91 .. 0.91
   4 ?    2.5   0.1     0.093   1.9e+02       6      21 ..     105     120 ..     104     121 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.43
                 TTBBBSSHHHHHCCT CS
  zf-C2H2_jaz  7 CdKyFksenaldnHl 21
                 C K F+  ++l  H+
   EEA20305.1 16 CGKSFNRKSDLCRHY 30
                 99****999998887 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.027
                 TTBBBSSHHHHHCC CS
  zf-C2H2_jaz  7 CdKyFksenaldnH 20
                 C+K F+  +al  H
   EEA20305.1 46 CNKSFIQRSALTVH 59
                 ******99999999 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.015
                 TTBBBSSHHHHHCCT CS
  zf-C2H2_jaz  7 CdKyFksenaldnHl 21
                 C K F+++++l  H 
   EEA20305.1 76 CRKAFSDSSSLARHR 90
                 *************97 PP

  == domain 4  score: 2.5 bits;  conditional E-value: 0.093
                  TTTBBBSSHHHHHCCT CS
  zf-C2H2_jaz   6 lCdKyFksenaldnHl 21 
                  +Cd+ F    +l +H+
   EEA20305.1 105 ACDRSFCRKTTLTKHQ 120
                  8*****9999999997 PP

>> zf-tcix  Putative treble-clef, zinc-finger, Zn-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   0.2    0.0018       3.5      21      40 ..       5      24 ..       2      26 .. 0.91
   2 ?   -1.7   0.0       1.1   2.3e+03      21      39 ..      65      83 ..      62      85 .. 0.75
   3 ?    3.1   0.2     0.036        71      20      36 ..      94     110 ..      92     115 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0018
     zf-tcix 21 GtRglsCkNkaCdqvfkkkd 40
                G+Rg+ C+ + C   f+ k+
  EEA20305.1  5 GSRGFNCSWERCGKSFNRKS 24
                9***************9986 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 1.1
     zf-tcix 21 GtRglsCkNkaCdqvfkkk 39
                G +  +C  ++C   f ++
  EEA20305.1 65 GEKPHVCDHEDCRKAFSDS 83
                6677789999999988765 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.036
     zf-tcix  20 NGtRglsCkNkaCdqvf 36 
                  G R  +C+ +aCd  f
  EEA20305.1  94 TGRRPYICSEPACDRSF 110
                 59999********9887 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.4     0.036        72       6      22 ..      16      32 ..      14      35 .. 0.86
   2 ?    3.4   0.2     0.053   1.1e+02       6      25 .]      46      63 ..      44      63 .. 0.86
   3 ?    2.6   0.1     0.095   1.9e+02       6      20 ..      76      90 ..      74      94 .. 0.87
   4 ?    6.5   0.5    0.0056        11       5      25 .]     105     124 ..     104     124 .. 0.90

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.036
      zf-met  6 CnvtfnsesqlksHlqG 22
                C ++fn +s+l  H++ 
  EEA20305.1 16 CGKSFNRKSDLCRHYRI 32
                **********9999986 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.053
      zf-met  6 CnvtfnsesqlksHlqGKkH 25
                Cn++f  +s+l  H  +++H
  EEA20305.1 46 CNKSFIQRSALTVH--SRTH 63
                ******99999888..7766 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.095
      zf-met  6 CnvtfnsesqlksHl 20
                C + f++ s+l  H 
  EEA20305.1 76 CRKAFSDSSSLARHR 90
                ************995 PP

  == domain 4  score: 6.5 bits;  conditional E-value: 0.0056
      zf-met   5 lCnvtfnsesqlksHlqGKkH 25 
                 +C+++f+ +++l  H q+++H
  EEA20305.1 105 ACDRSFCRKTTLTKH-QSRTH 124
                 7**************.77777 PP

>> TFIIA  Transcription factor IIA, alpha/beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2  12.9    0.0023       4.5     101     219 ..     122     253 ..      53     283 .. 0.44

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0023
       TFIIA 101 vqsltanssaataatfslpakleppvqipagvtlqtasg....qlykvnv.........qasgaqqiaaqplqqvvqqsqgsaaqssvaalqaqsqqaq 186
                  ++++ ++++ ++++  +p +++++  +++ +  +t+++    q y  n          q+++ +  ++qp++ v   +q ++a   ++++++q  + +
  EEA20305.1 122 RTHQPGGNTRPSSEEAPTPESMTYQTPVITTMAPNTTQYiiaqQPYYHNGptpttadfyQTPQPAIHFTQPQAMVP--QQIPTAGLPTPPFEPQ--HYA 216
                 2222212222222333333333332222222222222222223333333322212222233333333333332222..2333333344444433..333 PP

       TFIIA 187 alaepqqqlekq.....qqq.qqqqqqqqqqqqvqqqqq 219
                 +++++qqq   +     +q+ +q q q   +  v q+q 
  EEA20305.1 217 QIMQQQQQP--RydptpHQTyIQPQYQSPTPPFVAQHQH 253
                 333333331..1223342331222222222222222221 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (284 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       577  (0.0321825); expected 358.6 (0.02)
Passed bias filter:                      237  (0.0132188); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.41
# Mc/sec: 2095.48
//
Query:       EEA20306.1  [L=292]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.1e-17   63.4  33.5      5e-05   23.5   3.3    4.5  4  zf-C2H2      Zinc finger, C2H2 type
    1.4e-15   56.9  27.0    3.4e-06   27.2   1.0    5.2  6  zf-H2C2_2    Zinc-finger double domain
    1.2e-05   25.7  36.8      0.056   14.3   2.7    4.7  5  zf-C2H2_4    C2H2-type zinc finger
     0.0081   16.4  10.6      0.043   14.1   5.3    3.1  2  zf-C2H2_8    C2H2-type zinc ribbon
  ------ inclusion threshold ------
      0.011   16.3  12.0       0.67   10.6   0.2    4.3  4  FOXP-CC      FOXP coiled-coil domain
       0.48   10.8   7.5         32    5.0   0.0    4.2  4  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
       0.53    9.9   4.2        3.7    7.3   0.2    2.9  3  zf-tcix      Putative treble-clef, zinc-finger, Zn-binding
        1.5    9.3  13.8         12    6.5   0.5    4.5  4  zf-met       Zinc-finger of C2H2 type
        2.2    8.2  12.2        2.5    8.0  12.2    1.1  1  TFIIA        Transcription factor IIA, alpha/beta subunit


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   3.3   2.5e-08     5e-05       1      23 []       9      33 ..       9      33 .. 0.95
   2 !   18.4   1.9     1e-06    0.0021       1      23 []      39      63 ..      39      63 .. 0.95
   3 !   21.1   2.5   1.5e-07   0.00029       1      23 []      69      93 ..      69      93 .. 0.96
   4 !   18.0   2.9   1.4e-06    0.0028       1      23 []      99     124 ..      99     124 .. 0.93

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 2.5e-08
                EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCp..dCgksFkrksnLkrHirtH 23
                + C+   CgksF+rks+L+rH+r+H
  EEA20306.1  9 FNCSweRCGKSFNRKSDLCRHYRIH 33
                7899999*****************9 PP

  == domain 2  score: 18.4 bits;  conditional E-value: 1e-06
                EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCp..dCgksFkrksnLkrHirtH 23
                y C+   C+ksF ++s L++H rtH
  EEA20306.1 39 YHCTvpSCNKSFIQRSALTVHSRTH 63
                7899999*****************9 PP

  == domain 3  score: 21.1 bits;  conditional E-value: 1.5e-07
                EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCp..dCgksFkrksnLkrHirtH 23
                ++C+  dC k F+++s+L rH+r+H
  EEA20306.1 69 HVCDheDCRKAFSDSSSLARHRRIH 93
                68999*******************9 PP

  == domain 4  score: 18.0 bits;  conditional E-value: 1.4e-06
                 EEET..TTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirt.H 23 
                 y C+   C++sF+rk  L++H+++ H
  EEA20306.1  99 YICSepACDRSFCRKTTLTKHQSRtH 124
                 7788889****************999 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.0      0.13   2.7e+02      15      25 ..       9      21 ..       4      22 .. 0.80
   2 !   22.6   2.9   5.1e-08    0.0001       4      24 ..      28      50 ..      25      52 .. 0.93
   3 !   27.2   1.0   1.7e-09   3.4e-06       1      25 [.      55      81 ..      55      82 .. 0.94
   4 !   20.1   0.8   3.1e-07   0.00062       1      24 [.      85     115 ..      85     117 .. 0.75
   5 ?   -1.6   0.1       2.2   4.5e+03       2      10 ..     116     125 ..     115     127 .. 0.70
   6 ?   -2.4   0.0       4.2   8.3e+03       8      14 ..     168     174 ..     167     178 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.13
   zf-H2C2_2 15 yeCp..lCdkaFk 25
                ++C+   C+k+F+
  EEA20306.1  9 FNCSweRCGKSFN 21
                8899977*****8 PP

  == domain 2  score: 22.6 bits;  conditional E-value: 5.1e-08
   zf-H2C2_2  4 rHirkHtgekpyeCp..lCdkaF 24
                rH r Ht+e+py+C   +C+k+F
  EEA20306.1 28 RHYRIHTNERPYHCTvpSCNKSF 50
                9**************99*****9 PP

  == domain 3  score: 27.2 bits;  conditional E-value: 1.7e-09
   zf-H2C2_2  1 nLrrHirkHtgekpyeCp..lCdkaFk 25
                +L+ H r+Htgekp+ C+   C+kaF+
  EEA20306.1 55 ALTVHSRTHTGEKPHVCDheDCRKAFS 81
                6899***************99*****6 PP

  == domain 4  score: 20.1 bits;  conditional E-value: 3.1e-07
   zf-H2C2_2   1 nLrrHirkHtgekpy.....eCp..lCdkaF 24 
                 +L rH r Htg +py      C+  +C+k++
  EEA20306.1  85 SLARHRRIHTGRRPYicsepACDrsFCRKTT 115
                 589************6666666666666665 PP

  == domain 5  score: -1.6 bits;  conditional E-value: 2.2
   zf-H2C2_2   2 LrrHi.rkHt 10 
                 L++H+ r+H 
  EEA20306.1 116 LTKHQsRTHQ 125
                 8899735685 PP

  == domain 6  score: -2.4 bits;  conditional E-value: 4.2
   zf-H2C2_2   8 kHtgekp 14 
                  H g++p
  EEA20306.1 168 YHNGPTP 174
                 699*998 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   2.7   2.8e-05     0.056       1      23 [.       9      33 ..       9      34 .. 0.92
   2 !   11.3   1.4   0.00026      0.53       1      23 [.      39      63 ..      39      64 .. 0.93
   3 !   12.8   1.8   8.6e-05      0.17       2      23 ..      70      93 ..      69      94 .. 0.92
   4 !   10.4   2.2   0.00049      0.98       1      24 []      99     124 ..      99     124 .. 0.90
   5 ?   -3.3   0.4         9   1.8e+04      17      21 ..     252     256 ..     248     257 .. 0.68

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2.8e-05
   zf-C2H2_4  1 fkCpi..CgksFsskkaLlrHlkth 23
                f C++  CgksF++k++L+rH + h
  EEA20306.1  9 FNCSWerCGKSFNRKSDLCRHYRIH 33
                7799999***************998 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00026
   zf-C2H2_4  1 fkCpi..CgksFsskkaLlrHlkth 23
                + C++  C+ksF  ++aL  H +th
  EEA20306.1 39 YHCTVpsCNKSFIQRSALTVHSRTH 63
                6788888*****************9 PP

  == domain 3  score: 12.8 bits;  conditional E-value: 8.6e-05
   zf-C2H2_4  2 kCpi..CgksFsskkaLlrHlkth 23
                 C++  C+k Fs++++L rH + h
  EEA20306.1 70 VCDHedCRKAFSDSSSLARHRRIH 93
                799999**************9998 PP

  == domain 4  score: 10.4 bits;  conditional E-value: 0.00049
   zf-C2H2_4   1 fkCpi..CgksFsskkaLlrHlkthH 24 
                 ++C+   C++sF++k++L +H  + H
  EEA20306.1  99 YICSEpaCDRSFCRKTTLTKHQSRTH 124
                 7899999**************98877 PP

  == domain 5  score: -3.3 bits;  conditional E-value: 9
   zf-C2H2_4  17 lrHlk 21 
                 ++H++
  EEA20306.1 252 QHHMA 256
                 67885 PP

>> zf-C2H2_8  C2H2-type zinc ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.1   5.3   2.2e-05     0.043       2      87 ..      11      91 ..      10      95 .. 0.85
   2 !    5.8   1.6    0.0087        17       2      61 ..      71     124 ..      70     132 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 2.2e-05
   zf-C2H2_8  2 cssygcrlafpnvrelaqhlrvhlsptqslegklfrcstascaetfpsmqelvahtklhykpn.ryfkcencllrfrthrslfkhlh 87
                cs   c  +f    +l +h+r h +       + ++c+ +sc ++f     l  h++ h   +      e+c   f    sl +h  
  EEA20306.1 11 CSWERCGKSFNRKSDLCRHYRIHTN------ERPYHCTVPSCNKSFIQRSALTVHSRTHTGEKpHVCDHEDCRKAFSDSSSLARHRR 91
                999999**************99975......5789************************754413457799*999999999999965 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0087
   zf-C2H2_8   2 cssygcrlafpnvrelaqhlrvhlsptqslegklfrcstascaetfpsmqelvahtklhy 61 
                 c    cr af ++  la+h r h         + + cs ++c  +f     l  h    +
  EEA20306.1  71 CDHEDCRKAFSDSSSLARHRRIHTG------RRPYICSEPACDRSFCRKTTLTKHQSRTH 124
                 6677788888888888888877743......24578999999999998888888865554 PP

>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   0.6     0.016        33       6      27 ..      10      31 ..       7      39 .. 0.89
   2 ?    2.5   0.1      0.12   2.3e+02       6      28 ..      40      62 ..      37      69 .. 0.86
   3 ?    3.5   0.1     0.057   1.1e+02       6      26 ..      70      90 ..      67      95 .. 0.89
   4 ?   10.6   0.2   0.00034      0.67       6      36 ..     100     130 ..      98     135 .. 0.92

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.016
     FOXP-CC  6 vCkWPgCekvledveeflkhln 27
                 C W  C k ++  +++ +h +
  EEA20306.1 10 NCSWERCGKSFNRKSDLCRHYR 31
                5*******************75 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.12
     FOXP-CC  6 vCkWPgCekvledveeflkhlns 28
                +C  P C+k + + ++++ h ++
  EEA20306.1 40 HCTVPSCNKSFIQRSALTVHSRT 62
                6999***********99999765 PP

  == domain 3  score: 3.5 bits;  conditional E-value: 0.057
     FOXP-CC  6 vCkWPgCekvledveeflkhl 26
                vC+  +C k+++d++++ +h 
  EEA20306.1 70 VCDHEDCRKAFSDSSSLARHR 90
                79999**************95 PP

  == domain 4  score: 10.6 bits;  conditional E-value: 0.00034
     FOXP-CC   6 vCkWPgCekvledveeflkhlnseHalddks 36 
                 +C  P C++ +   ++++kh +++H+++ ++
  EEA20306.1 100 ICSEPACDRSFCRKTTLTKHQSRTHQPGGNT 130
                 5999**********************98765 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.3      0.44   8.8e+02       7      21 ..      16      30 ..      16      31 .. 0.86
   2 ?    4.2   0.1     0.028        56       7      20 ..      46      59 ..      44      69 .. 0.84
   3 ?    5.0   0.0     0.016        32       7      21 ..      76      90 ..      74      91 .. 0.91
   4 ?    2.5   0.1     0.096   1.9e+02       6      21 ..     105     120 ..     104     121 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.44
                 TTBBBSSHHHHHCCT CS
  zf-C2H2_jaz  7 CdKyFksenaldnHl 21
                 C K F+  ++l  H+
   EEA20306.1 16 CGKSFNRKSDLCRHY 30
                 99****999998887 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.028
                 TTBBBSSHHHHHCC CS
  zf-C2H2_jaz  7 CdKyFksenaldnH 20
                 C+K F+  +al  H
   EEA20306.1 46 CNKSFIQRSALTVH 59
                 ******99999999 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.016
                 TTBBBSSHHHHHCCT CS
  zf-C2H2_jaz  7 CdKyFksenaldnHl 21
                 C K F+++++l  H 
   EEA20306.1 76 CRKAFSDSSSLARHR 90
                 *************97 PP

  == domain 4  score: 2.5 bits;  conditional E-value: 0.096
                  TTTBBBSSHHHHHCCT CS
  zf-C2H2_jaz   6 lCdKyFksenaldnHl 21 
                  +Cd+ F    +l +H+
   EEA20306.1 105 ACDRSFCRKTTLTKHQ 120
                  8*****9999999997 PP

>> zf-tcix  Putative treble-clef, zinc-finger, Zn-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   0.2    0.0018       3.7      21      40 ..       5      24 ..       2      26 .. 0.91
   2 ?   -1.7   0.0       1.2   2.4e+03      21      39 ..      65      83 ..      62      85 .. 0.75
   3 ?    3.1   0.2     0.037        74      20      36 ..      94     110 ..      92     115 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0018
     zf-tcix 21 GtRglsCkNkaCdqvfkkkd 40
                G+Rg+ C+ + C   f+ k+
  EEA20306.1  5 GSRGFNCSWERCGKSFNRKS 24
                9***************9986 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 1.2
     zf-tcix 21 GtRglsCkNkaCdqvfkkk 39
                G +  +C  ++C   f ++
  EEA20306.1 65 GEKPHVCDHEDCRKAFSDS 83
                6677789999999988765 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.037
     zf-tcix  20 NGtRglsCkNkaCdqvf 36 
                  G R  +C+ +aCd  f
  EEA20306.1  94 TGRRPYICSEPACDRSF 110
                 59999********9887 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.4     0.037        74       6      22 ..      16      32 ..      14      35 .. 0.86
   2 ?    3.4   0.2     0.055   1.1e+02       6      25 .]      46      63 ..      44      63 .. 0.86
   3 ?    2.6   0.1     0.098     2e+02       6      20 ..      76      90 ..      74      94 .. 0.87
   4 ?    6.5   0.5    0.0058        12       5      25 .]     105     124 ..     104     124 .. 0.90

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.037
      zf-met  6 CnvtfnsesqlksHlqG 22
                C ++fn +s+l  H++ 
  EEA20306.1 16 CGKSFNRKSDLCRHYRI 32
                **********9999986 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.055
      zf-met  6 CnvtfnsesqlksHlqGKkH 25
                Cn++f  +s+l  H  +++H
  EEA20306.1 46 CNKSFIQRSALTVH--SRTH 63
                ******99999888..7766 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.098
      zf-met  6 CnvtfnsesqlksHl 20
                C + f++ s+l  H 
  EEA20306.1 76 CRKAFSDSSSLARHR 90
                ************995 PP

  == domain 4  score: 6.5 bits;  conditional E-value: 0.0058
      zf-met   5 lCnvtfnsesqlksHlqGKkH 25 
                 +C+++f+ +++l  H q+++H
  EEA20306.1 105 ACDRSFCRKTTLTKH-QSRTH 124
                 7**************.77777 PP

>> TFIIA  Transcription factor IIA, alpha/beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0  12.2    0.0012       2.5     100     220 ..     121     254 ..      53     287 .. 0.45

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0012
       TFIIA 100 svqsltanssaataatfslpakleppvqipagvtlqtasg....qlykvnv.........qasgaqqiaaqplqqvvqqsqgsaaqssvaalqaqsqqa 185
                 s ++++ ++++ ++++  +p +++++  +++ +  +t+++    q y  n          q+++ +  ++qp++ v   +q ++a   ++++++q  + 
  EEA20306.1 121 SRTHQPGGNTRPSSEEAPTPESMTYQTPVITTMAPNTTQYiiaqQPYYHNGptpttadfyQTPQPAIHFTQPQAMVP--QQIPTAGLPTPPFEPQ--HY 215
                 22222212222233333333333332222222222222223323444333322222222233333333333333332..2344444444444443..33 PP

       TFIIA 186 qalaepqqqlekq.....qqq.qqqqqqqqqqqqvqqqqqe 220
                 ++++++qqq   +     +q+ +q q q   +  v q+q +
  EEA20306.1 216 AQIMQQQQQP--RydptpHQTyIQPQYQSPTPPFVAQHQHH 254
                 3333333331..12234433312222222222222222221 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (292 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       599  (0.0334096); expected 358.6 (0.02)
Passed bias filter:                      255  (0.0142228); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 1897.62
//
Query:       EEA20307.1  [L=844]
Description: alpha-glucuronidase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.1e-147  491.3   0.1   1.7e-147  490.7   0.1    1.2  1  Glyco_hydro_67M  Glycosyl hydrolase family 67 middle domain
    1.5e-90  302.7   3.3    2.2e-90  302.1   3.3    1.3  1  Glyco_hydro_67C  Glycosyl hydrolase family 67 C-terminus
      1e-29  103.3   0.0      2e-29  102.3   0.0    1.5  1  Glyco_hydro_67N  Glycosyl hydrolase family 67 N-terminus
  ------ inclusion threshold ------
      0.037   14.8   0.0       0.11   13.3   0.0    1.8  1  Glyco_hydro_20b  Glycosyl hydrolase family 20, domain 2


Domain annotation for each model (and alignments):
>> Glyco_hydro_67M  Glycosyl hydrolase family 67 middle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  490.7   0.1  3.8e-151  1.7e-147       7     325 .]     152     470 ..     147     470 .. 0.99

  Alignments for each domain:
  == domain 1  score: 490.7 bits;  conditional E-value: 3.8e-151
                      --TT-EEEE--SSSEEEEE--B-TTS-BTT--S-S-S.--CCCTTT---HHHHHHHHHHTTT--EEE-S-SS--GGGGSHHHHHHHHHHHHHHG CS
  Glyco_hydro_67M   7 sleeleiaekPkaklRllnhWdnldgsvERgyaGesiffeeeklaedldrvkdyarllasvgingvvlnnvnakaklltkeylekvaaladvlr 100
                      + ++++++++P+a++R++n+Wdnldgs+ERgy+G+siff+++ ++++l+r+++yarllas+g+n+vv+nnvna+++llt+e+++ + ++adv+r
       EEA20307.1 152 NFSDVAYTSNPHAHIRWVNQWDNLDGSIERGYGGASIFFKNDVVVANLTRATEYARLLASIGLNAVVVNNVNANSSLLTPENIQGLGRIADVFR 245
                      4567799*************************************************************************************** PP

                      GGT-EEEEEE-TTHHHHTTS-S---TTSHHHHHHHHHHHHHHHHH-TT--EEEE--SBTTB--GGGGT--HHHHHHHHHHHHGGGT-EEEEE-- CS
  Glyco_hydro_67M 101 pygikvylsvnfaapielggletadPldeevkkwWkekvkeiyeaipdfgGflvkAdsEgqpGPltygrthadganmlaealkpyggiviwRaF 194
                      pyg+++ +s+nfa+p+++ggl+t+dPld+ v+k+W++ ++++y+a+pd++G+lvkAdsEgq+GPl y+rt ++gan++a+alkp+ggi+++RaF
       EEA20307.1 246 PYGVQLGISLNFATPQQIGGLNTYDPLDQGVIKFWTNITDQLYKAVPDMAGYLVKADSEGQAGPLVYNRTLSQGANLFANALKPHGGILMYRAF 339
                      ********************************************************************************************** PP

                      ---.....TTSS-GGGHHHHHHGGGTT-S-TTEEEEEESSSSSS-SS----THHHH-SSSEEEEEEE-S-TTTTTTTS----HHHHHHHHT-B- CS
  Glyco_hydro_67M 195 vYnaqdwrdkkedRakaayeeFkpldgkfkdnvilqiknGpiDfqvrEpvsplfgalektnlalElqitqEylGqqthlvylaplwkevldfdt 288
                      vYn+++++++k+dRa+aa+e Fk+ldg+f+dnvi+qik+GpiDfqvrEp+splf++l +tn+a+Elqi+qEylGqq+hlvyl plwk++ldfd+
       EEA20307.1 340 VYNQLNESNWKADRANAAVEFFKDLDGEFEDNVIVQIKYGPIDFQVREPASPLFANLLNTNTAIELQIAQEYLGQQCHLVYLPPLWKTILDFDL 433
                      ********************************************************************************************** PP

                      -TTSTT-BHHHHHTTTTTT-S-EEEEEE----SSTTS CS
  Glyco_hydro_67M 289 yakgegstvkkvvdgklfkkkltgiagvanvGedenW 325
                      ++++++s+v+++v+g++f+++l+g+agv+nvG++++W
       EEA20307.1 434 RVESKQSRVSDIVSGERFNRSLGGFAGVVNVGTNTTW 470
                      ************************************* PP

>> Glyco_hydro_67C  Glycosyl hydrolase family 67 C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  302.1   3.3   4.9e-94   2.2e-90       2     222 ..     472     694 ..     471     695 .. 0.99

  Alignments for each domain:
  == domain 1  score: 302.1 bits;  conditional E-value: 4.9e-94
                      SSTTHHHHHHHHHHHHH-TT--HHHHHHHHHHHHT---HHHHHHHHHHHHHHHHHHHHTT--TT----B-TTT.-SSB-T--SSSGGGSSHH-- CS
  Glyco_hydro_67C   2 GhplaqanlYafGrlawdpelsseeiaeeWirltfskdeevvetvkellleSreayvnYtaplGlhhlvkagh.Hygpepdkaersdwgtyhra 94 
                      G++la++nlYa+G+law+p  ++++i+++W+rltf+ d++vv+t++e+++eS++ay++Y+ +lG+++l+++ + H+gp+p++++++ wg+++ra
       EEA20307.1 472 GSHLAMSNLYAYGQLAWNPARDPADIIQDWTRLTFELDQHVVDTITEMSMESWPAYESYSGNLGIQTLTDILYtHFGPNPASQDNNGWGQWTRA 565
                      99*********************************************************************888******************** PP

                      -SSEEE---S.TTTT-GGGGS-HHHHHHHHSTTTS-GGGGGGT-EEETT-B-TTS-BHHHHHHHHHHHHHHHHHHHHHHHHCCCCCS-HHHHHH CS
  Glyco_hydro_67C  95 dkkgiGvdRt.atGtgavaqYaeelaeeyedletcpeelLLwfHhvpythklksGktliqelydayfegveeveelqktweslegkideerfee 187
                      d+++iG+dRt ++Gtg+++qY++e++++ye++et+p++lLLwfHhvpyt+kl+sGkt+iq++yda+++g+++++++ ++wesl+++id+er+++
       EEA20307.1 566 DHTSIGMDRTvSNGTGYSGQYPPEISSMYENIETTPDDLLLWFHHVPYTQKLQSGKTVIQHFYDAHYTGAATAQTFPTKWESLKNRIDKERYNH 659
                      ********************************************************************************************** PP

                      HHHHHHHHHHHHHHHHHHHHHHHHHHH-----TTS CS
  Glyco_hydro_67C 188 vkerleiqaeeakeWrdailtYfqrfskipdekgr 222
                      v +rl++qa ++ +Wrdai ++++++s ipde+gr
       EEA20307.1 660 VLYRLAYQAGHSIVWRDAISEFYHNLSAIPDEAGR 694
                      *******************************9987 PP

>> Glyco_hydro_67N  Glycosyl hydrolase family 67 N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.3   0.0   4.5e-33     2e-29       1     122 []      24     144 ..      24     144 .. 0.91

  Alignments for each domain:
  == domain 1  score: 102.3 bits;  conditional E-value: 4.5e-33
                      TT------S-HHHHHHHHHH-SEEEE---S..HHHHHHHHHHHHHHHHHHTS---.EE-SS--SSE..EEEE-TTT-HHHHHT--THHHHTTTT CS
  Glyco_hydro_67N   1 lWLrYapiedaalkekykalpsaivvlnat..stievakqELkeglkgilgkelk.vsseekkess..ilvgtleelaeieslalpeeleelge 89 
                      +WLrYap++ + + +  +++ps+iv+ln++  s++++a+qEL++g++gil k+++ v+s++++++s  i+vgt+++++e  +  ++++  +l e
       EEA20307.1  24 GWLRYAPLPASLASHFPHDFPSSIVALNSSvnSPVYTAAQELQKGFQGILHKPIDiVNSTKDHSHSssIVVGTADAYTE--AFGTGTNWGDLIE 115
                      6************9999************999**********************95555555555578**********9..6777777888*** PP

                      T-EEEEEEEETTEEEEEEEESSHHHHHHHHHHH CS
  Glyco_hydro_67N  90 eGfllktveveekksvvivgqterGvLYGaFey 122
                      +Gf+l+t    +k+sv+i+gq+erG+LYG+Fey
       EEA20307.1 116 DGFWLHT----SKDSVQIIGQNERGALYGTFEY 144
                      *******....*********************9 PP

>> Glyco_hydro_20b  Glycosyl hydrolase family 20, domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   2.4e-05      0.11      20     110 ..      50     150 ..      41     167 .. 0.74

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 2.4e-05
  Glyco_hydro_20b  20 lgsevtivveeaadeatadllaevlkaatgirlteakepgkgdirllalkd...........aelgaEgYrLavdedtitiegkdtdGlfyGvq 102
                      l+s+v+  v   a+++ ++ ++ +l++  +i  ++++ + + +i + ++++            +l ++g+ L   +d++ i g++++G++yG+ 
       EEA20307.1  50 LNSSVNSPVYT-AAQELQKGFQGILHKPIDIVNSTKDHSHSSSIVVGTADAyteafgtgtnwGDLIEDGFWLHTSKDSVQIIGQNERGALYGTF 142
                      55555555555.66777777777777555555556666667777666555578888889999******************************96 PP

  Glyco_hydro_20b 103 TLrqllpq 110
                        + +l q
       EEA20307.1 143 EYLSMLAQ 150
                      66666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (844 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       507  (0.0282782); expected 358.6 (0.02)
Passed bias filter:                      436  (0.0243181); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.68u 0.27s 00:00:00.95 Elapsed: 00:00:00.44
# Mc/sec: 5801.95
//
Query:       EEA20308.1  [L=445]
Description: 3-ketosteroid reductase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.1e-10   40.4   0.0    3.4e-07   29.9   0.0    3.1  1  adh_short     short chain dehydrogenase
  ------ inclusion threshold ------
       0.16   11.9   0.0       0.27   11.1   0.0    1.3  1  KR            KR domain
       0.17   11.4   0.0        3.4    7.1   0.0    2.2  2  adh_short_C2  Enoyl-(Acyl carrier protein) reductase


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.9   0.0   5.6e-11   3.4e-07       2     144 ..      28     227 ..      27     246 .. 0.80

  Alignments for each domain:
  == domain 1  score: 29.9 bits;  conditional E-value: 5.6e-11
                 EEEEESTTSHHHHHHHHHHHHTT-E..........EEE.EESCHHHHHHHHHHHHHT....TSE......EEEEE-TTTSHHHHHHHHHHHHHHHSSES CS
   adh_short   2 vvlvtGassGIGraiakelakeGak..........vvv.vdrseekleevakelkee....gak......alaiqvDvtdreevealvekavkklgkld 79 
                 vvlvtGa sG+G+a++ +l+ e ak          +++ + r +++++++++ ++++    g +      +la +vD+ +  +v+al  +   ++ kld
  EEA20308.1  28 VVLVTGANSGLGYATCLRLIDEFAKdpannhkqltLIFtTRRPPAQVQTLKNDMRKHalilGPQvssrinILAETVDLLNLPSVRALSIRLNRNFPKLD 126
                 8***************999865332222222222255546677777888888887767777333333444788899999******************** PP

                 EEEE---S..................................S--SSGGGCSHHH.HHHHHHHHTHHHHHHHHHHHHHHH.HCTTEEEEEEEEGGGTSB CS
   adh_short  80 vLvnNAGi..................................tgsgpfselseee.wervievNltgvflltravlpaml.kqssGrIvnvsSvagkvp 142
                  ++ NAGi                                    + ++ +  +e+   +v+  N++g ++l++ v+p +  +++ Gr++ vsS+ ++++
  EEA20308.1 127 SIILNAGIggwsgidwpsaiwnvctdllhsatwptfklgyvgMVVPNQTHQPDEKpLGSVFCANVFGHYMLAHNVMPLLRrSKNPGRVIWVSSIEAREE 225
                 *******************99999999999999999999996333333344444459999******************9988999*********99877 PP

                 -T CS
   adh_short 143 va 144
                 ++
  EEA20308.1 226 SF 227
                 65 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   4.5e-05      0.27       2      91 ..      28     134 ..      27     141 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 4.5e-05
                 EEEEETTTSHHHHHHHHHHHH.........HHS-EEEEE-SS.......--HHHHHHHHHHHHTT-..........EEEE----TT-HHHHHHHHHHHH CS
          KR   2 tylitGGlGgLGlelarwlae.........kgarhlvllsRsa.....aadedskaliaelealga..........evevvaaDvsdkdavealleeik 76 
                 ++l+tG+  gLG +++  l++         + + +l++++R++     +       l + ++++            ++ +  +D+ +  +v+al  +++
  EEA20308.1  28 VVLVTGANSGLGYATCLRLIDefakdpannHKQLTLIFTTRRPpaqvqT-------LKNDMRKHALilgpqvssriNILAETVDLLNLPSVRALSIRLN 119
                 689************99999866667666455668999****6444441.......33333333222333334444999999***************** PP

                 HHSS---EEEE---- CS
          KR  77 aeeppikGvihaAgv 91 
                 +++p++  +i  Ag+
  EEA20308.1 120 RNFPKLDSIILNAGI 134
                 ***********9998 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.0     0.023   1.4e+02      47      82 ..     102     137 ..      75     157 .. 0.84
   2 ?    7.1   0.0   0.00058       3.4      85     133 ..     173     224 ..     162     239 .. 0.81

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.023
                   E--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EG CS
  adh_short_C2  47 ecDVtdeeqvealveevvekfgklDilvnnagiapk 82 
                    +D  +  +v+al  ++ ++f klD ++ nagi   
    EEA20308.1 102 TVDLLNLPSVRALSIRLNRNFPKLDSIILNAGIGGW 137
                   5677777889999999****************9865 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.00058
                   S-GGGH-HHHHHHHHHHHTHHHHHHHHHHHHHCTSC...CEEEEEEEGGGTS CS
  adh_short_C2  85 gpfletsreefdraldvnlyslfllakaalplmkeg...gsivnlssvgaer 133
                   +++++ +++ +  ++  n+ + ++la+ ++pl++++   g+++ +ss+ a+ 
    EEA20308.1 173 NQTHQPDEKPLGSVFCANVFGHYMLAHNVMPLLRRSknpGRVIWVSSIEARE 224
                   55566667777789999**************88776689*********9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (445 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       294  (0.016398); expected 358.6 (0.02)
Passed bias filter:                      268  (0.0149478); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 3207.51
//
Query:       EEA20309.1  [L=801]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.3e-10   38.9  13.0    2.5e-09   37.1  13.0    2.0  1  Cnn_1N          Centrosomin N-terminal motif 1
     0.0007   18.1  12.0      0.001   17.6  12.0    1.1  1  MAD             Mitotic checkpoint protein
  ------ inclusion threshold ------
      0.033   12.1   1.1      0.048   11.6   1.1    1.1  1  Prominin        Prominin
      0.053   13.5   1.2       0.17   11.9   1.2    1.9  1  G-gamma         GGL domain
       0.11   13.0   9.4       0.24   11.9   9.4    1.5  1  AAA_23          AAA domain
       0.11   13.2   0.3       0.11   13.2   0.3    3.6  4  DUF4666         Domain of unknown function (DUF4666)
       0.47   11.1  11.4       0.68   10.6   9.9    2.0  1  YabA            Initiation control protein YabA
        0.5   10.4  12.9        1.3    9.1  12.9    1.7  1  UPF0242         Uncharacterised protein family (UPF0242) N-te
       0.52    9.8   3.0        1.1    8.8   3.0    1.5  1  Fzo_mitofusin   fzo-like conserved region
       0.63    9.3   7.7       0.72    9.1   3.3    2.3  2  HemX            HemX, putative uroporphyrinogen-III C-methylt
        0.7    8.8   2.7        5.6    5.8   3.5    1.8  2  Seadorna_VP6    Seadornavirus VP6 protein
        1.7    8.1   9.3        3.7    7.0   9.3    1.5  1  Exonuc_VII_L    Exonuclease VII, large subunit
        7.3    6.7   8.3         14    5.8   2.3    2.3  2  DUF1664         Protein of unknown function (DUF1664)


Domain annotation for each model (and alignments):
>> Cnn_1N  Centrosomin N-terminal motif 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.1  13.0   1.8e-12   2.5e-09       2      69 ..      96     185 ..      95     189 .. 0.96

  Alignments for each domain:
  == domain 1  score: 37.1 bits;  conditional E-value: 1.8e-12
      Cnn_1N   2 lrEqeeqidkLkKENFdLKLri.................yfLeerleklse.....eqkeellkenielkveveslqkelkekkkllrea 69 
                 +rE++++++k++K NFdLKL+i                 +++ee+l+++++     ++ +e++++n  l++e+e+lq el+++++ + ea
  EEA20309.1  96 IREMDQYVSKMNKLNFDLKLEIfhrkeqiaglekrmermHEMEEELKRMHDledelDELREVEENNQRLREENEQLQSELDRRDQAISEA 185
                 7****************************9999999999999999999999**********************************99987 PP

>> MAD  Mitotic checkpoint protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6  12.0   7.4e-07     0.001     162     262 ..      96     200 ..      28     204 .. 0.83

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 7.4e-07
         MAD 162 qkelaeaeqrikeLefeiqs.qeddslivknskselaripelekeler...lreenkklnelkenkelLkEevedlkkkLereEkareelvkLelekek 256
                  +e+ +   ++  L+f +++   + ++ +   +++++r+ e+e+el+r   l+ e  +l+e++en++ L+Ee e+l++ L+r  +a  e+v+L   +e 
  EEA20309.1  96 IREMDQYVSKMNKLNFDLKLeIFHRKEQIAGLEKRMERMHEMEEELKRmhdLEDELDELREVEENNQRLREENEQLQSELDRRDQAISEAVELICHLEA 194
                 556666677888888888875567788889999*************9933345788999**********************************998887 PP

         MAD 257 leqeLk 262
                   +eL+
  EEA20309.1 195 KVEELQ 200
                 777776 PP

>> Prominin  Prominin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   1.1   3.5e-05     0.048     235     322 ..     135     222 ..      98     228 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 3.5e-05
    Prominin 235 lpaLaelerllenlkeakeqLeqvnklekeLrksgsqLrdglrgvkrdlnqalsnlCqs.eeCskilssleiekldtskcldqlpnvde 322
                  ++ +el+r+  +l++  ++L++v+++ ++Lr++ +qL++ l    + +++a++  C+  ++ +++++   ++ l  +  ++++ +v+e
  EEA20309.1 135 HEMEEELKRMH-DLEDELDELREVEENNQRLREENEQLQSELDRRDQAISEAVELICHLeAKVEELQTGRGTTPLPKDGGFNAVADVSE 222
                 33344555543.456667889*************************************5488888888777777777777766666665 PP

>> G-gamma  GGL domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   1.2   0.00012      0.17       2      32 ..     159     189 ..     158     191 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00012
     G-gamma   2 qlklklkreieqLkkeLkrerikvSkAceel 32 
                 +++++l +e eqL++eL+r+ + +S+A+e +
  EEA20309.1 159 ENNQRLREENEQLQSELDRRDQAISEAVELI 189
                 5789999999*****************9865 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   9.4   0.00018      0.24      92     195 ..      74     174 ..      25     185 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00018
      AAA_23  92 rerelskkkgkttkkaklelleideleqfisellgskkiilnlilflgqerfeefelkdkkerleelekeleeledekkllekleqekekekeleelee 190
                  e++++ ++  +  +++ + ++i+e +q++s+ +++ +  l+l +f+ +e+     l+++ er+ e+e+el+   d +++l++l + +e++++l e +e
  EEA20309.1  74 SEKQRRINSFASSGQKQPRDMGIREMDQYVSK-MNKLNFDLKLEIFHRKEQI--AGLEKRMERMHEMEEELKRMHDLEDELDELREVEENNQRLREENE 169
                 56677777777888888889999999999997.4555555888888888873..234566688888888888888888888888777777776666666 PP

      AAA_23 191 eleei 195
                 +l++ 
  EEA20309.1 170 QLQSE 174
                 66653 PP

>> DUF4666  Domain of unknown function (DUF4666)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   1.2       3.8   5.3e+03      43      74 ..     144     174 ..     117     188 .. 0.48
   2 ?   13.2   0.3   7.8e-05      0.11      66     106 ..     267     313 ..     224     317 .. 0.65
   3 ?   -2.0   0.0       4.3   5.9e+03      64      83 ..     365     384 ..     331     386 .. 0.68
   4 ?   -2.7   0.0       7.1   9.8e+03      87      97 ..     522     532 ..     486     544 .. 0.78

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 3.8
     DUF4666  43 aeeeeakelrhsrsvgsigslersrsnggsaq 74 
                  ++ e  el++ r+v++  +  r+++++ +++
  EEA20309.1 144 MHDLED-ELDELREVEENNQRLREENEQLQSE 174
                 222222.4555555555444444444444333 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 7.8e-05
     DUF4666  66 s......rsnggsaqrvfrtkrvsPavdPpsPrvsacilCsifgkkg 106
                 s      +++ +s + + r  +v    dPpsPr+s    Cs f  ++
  EEA20309.1 267 SlflqeeNKSVRSVSASTRGTTVDSIADPPSPRLSILSECSYFAPHD 313
                 133332233333455577889999******************98665 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 4.3
     DUF4666  64 ersrsnggsaqrvfrtkrvs 83 
                 +rs+++++s+ + +r++ vs
  EEA20309.1 365 QRSSQRKTSNGNRYRARAVS 384
                 55666666677789999886 PP

  == domain 4  score: -2.7 bits;  conditional E-value: 7.1
     DUF4666  87 dPpsPrvsaci 97 
                  P sPr+s  +
  EEA20309.1 522 SPSSPRISCYG 532
                 69999998765 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   9.9   0.00049      0.68       7      61 ..     131     184 ..     126     201 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00049
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHXXXXXXXXX CS
        YabA   7 fdkleeleeqleelleeleelkeelaelleenaeLeleneklrerleeeekkeke 61 
                 +++++e+ee+l+++++  +el +el e+ e+n++L+ ene+l+++l++++++ +e
  EEA20309.1 131 MERMHEMEEELKRMHDLEDEL-DELREVEENNQRLREENEQLQSELDRRDQAISE 184
                 689999999999998655555.7899********************766665544 PP

>> UPF0242  Uncharacterised protein family (UPF0242) N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1  12.9   0.00093       1.3      81     182 ..      84     199 ..      55     201 .. 0.62

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00093
     UPF0242  81 d.........eglktkeealeelqeeeeeLkeeldakeeelerlkeenqqLqekleaiaedfeelkleleeqLaekqellqeyqetieeqrsvlekrqd 170
                            g+++ ++ + ++++ + +Lk e+ +++e+++ l+++ + ++e  e+  + +++l  el+ +L+e +e  q ++e+ e+++s+l++r++
  EEA20309.1  84 AssgqkqprdMGIREMDQYVSKMNKLNFDLKLEIFHRKEQIAGLEKRMERMHEMEEE-LKRMHDLEDELD-ELREVEENNQRLREENEQLQSELDRRDQ 180
                 444444544456777777888888888888888888888888888887777744443.445555555554.3666666677777777777777777776 PP

     UPF0242 171 qie.......qLeskVrDl 182
                  i+       +Le+kV+ l
  EEA20309.1 181 AISeavelicHLEAKVEEL 199
                 6542222222577777655 PP

>> Fzo_mitofusin  fzo-like conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   3.0   0.00078       1.1     110     154 ..     134     177 ..      94     182 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00078
  Fzo_mitofusin 110 vdetekeleeeikelekeiekleevqkkakllrnkaslleseLek 154
                     +e+e+el+ ++++le e+++l ev+++ + lr++ ++l+seL++
     EEA20309.1 134 MHEMEEELK-RMHDLEDELDELREVEENNQRLREENEQLQSELDR 177
                    334444443.4567899**************************97 PP

>> HemX  HemX, putative uroporphyrinogen-III C-methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   3.3   0.00053      0.72      33     100 ..     133     200 ..     116     207 .. 0.80
   2 ?    1.8   0.1     0.088   1.2e+02     186     239 ..     326     383 ..     323     387 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00053
        HemX  33 ltaevaelqqqlaaleqqlaqveaekeqkqeleerlqqlaeklealekeleqlqkqleelqqqlskvs 100
                    e++e  ++++ le++l+++++ +e++q+l e+ +ql+++l+++ +++++  + + +l++++++++
  EEA20309.1 133 RMHEMEEELKRMHDLEDELDELREVEENNQRLREENEQLQSELDRRDQAISEAVELICHLEAKVEELQ 200
                 33444666677888888888899999999999999999999999999999999999999999999986 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.088
        HemX 186 qvdeLpladnelde....apsdadnaelsdslsdWkqnleksaksflshfirirrrdk 239
                 ++d+++l++ne ++      +d +n++lsd +sdW  + ++s ++  s+  r+r r+ 
  EEA20309.1 326 RLDQMTLVNNEHSAvaatPTKDLHNGHLSDRISDWMYFDQRSSQRKTSNGNRYRARAV 383
                 678888888877663321235678999**************99999998888888774 PP

>> Seadorna_VP6  Seadornavirus VP6 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   3.5    0.0041       5.6      22      79 ..     143     197 ..     125     202 .. 0.75
   2 ?   -0.9   0.0      0.45   6.2e+02     146     178 ..     587     619 ..     582     624 .. 0.87

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0041
  Seadorna_VP6  22 enqelegvsfdelvalreenaklkqenealkaklhrlesdwttsdivekvelmdaqfd 79 
                     ++le   +del  + e+n +l++ene l+++l r   d + s+ ve +  ++a+++
    EEA20309.1 143 RMHDLED-ELDELREVEENNQRLREENEQLQSELDRR--DQAISEAVELICHLEAKVE 197
                   3445554.6899***********************96..6678888888877777765 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.45
  Seadorna_VP6 146 ekmiksfeyddiadtialrlthfiqdpglrsiv 178
                   ek+ + f  dd ad i++  +h  ++p lr   
    EEA20309.1 587 EKLHEEFGKDDSADEITIEDAHTPRNPPLRLHA 619
                   899999*********************999655 PP

>> Exonuc_VII_L  Exonuclease VII, large subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   9.3    0.0027       3.7     129     257 ..      16     172 ..      11     200 .. 0.64

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0027
  Exonuc_VII_L 129 pTPtaaAelvvpdkaeleeqleelerrlekaikrll......................eekkqrleklasrlk.speellerkrqrldeleerlera 202
                   +T t    lv p ++ l++ ++e+++  +   + +l                      +ek++r++++as+ + +p+++  r+ +++ +  ++l+  
    EEA20309.1  16 STDTSSTTLVNPTSTILQDLIKEQRATRSARKTPQLsedvdnrpttagsqpltaenspSEKQRRINSFASSGQkQPRDMGIREMDQYVSKMNKLNFD 112
                   5555555566655555544444444422222222223444444466666666777777889999999988886588887777766666667888888 PP

  Exonuc_VII_L 203 lkkqlkkkrerleelkerl.k.ekleekkerlkklkerle...lleekkerleeleekle 257
                   lk ++ +++e++  l++r+ + +++ee+ +r+++l+++l+   ++ee+++rl+e  e+l+
    EEA20309.1 113 LKLEIFHRKEQIAGLEKRMeRmHEMEEELKRMHDLEDELDelrEVEENNQRLREENEQLQ 172
                   888899999999999988855766666666666666666655545555555555555554 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.7     0.048        66      67     114 ..      95     142 ..      81     151 .. 0.83
   2 ?    5.8   2.3      0.01        14      49      93 ..     156     200 ..     144     205 .. 0.69

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.048
     DUF1664  67 ridrvdkkldeqkeiskeikeevtevredlseigedvesvkeavegle 114
                  i ++d+ + +++++  ++k e+ + +e+++ +++ +e ++e+ e+l+
  EEA20309.1  95 GIREMDQYVSKMNKLNFDLKLEIFHRKEQIAGLEKRMERMHEMEEELK 142
                 588999999999999999999999999999999999999999988885 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.01
     DUF1664  49 qleqvseslaatkrhLssridrvdkkldeqkeiskeikeevtevr 93 
                 ++e+  + l++  ++L+s++dr d+ + e  e++ +++++v+e++
  EEA20309.1 156 EVEENNQRLREENEQLQSELDRRDQAISEAVELICHLEAKVEELQ 200
                 345556677777777777777777777777777777777777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (801 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1542  (0.0860059); expected 358.6 (0.02)
Passed bias filter:                      672  (0.0374812); expected 358.6 (0.02)
Passed Vit filter:                       115  (0.00641419); expected 17.9 (0.001)
Passed Fwd filter:                        23  (0.00128284); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.90u 0.32s 00:00:01.22 Elapsed: 00:00:00.47
# Mc/sec: 5075.20
//
Query:       EEA20310.1  [L=179]
Description: GINS complex subunit Psf3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.8e-22   79.9   0.0    2.4e-22   79.5   0.0    1.2  1  Sld5      GINS complex protein


Domain annotation for each model (and alignments):
>> Sld5  GINS complex protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.5   0.0   1.3e-26   2.4e-22       1     109 []      44     155 ..      44     155 .. 0.98

  Alignments for each domain:
  == domain 1  score: 79.5 bits;  conditional E-value: 1.3e-26
                 EEEEHHHHHHHH......HTTSCCCHHCHHHCHHHHHHCCCHHTTSSSSTTTTTTHHHHHHHHHHHHT.HCHHHHHHHHHHHHHHHHHHHTHCHHHHHH CS
        Sld5   1 veLPlWlaelLk......rqrrveieppewlspesleailedetkssdlpslpphflelavkllelardldelkrllrdllevRlakirkfaenledaa 93 
                 v+LPlWl e+L+       +r v++++p  ls+++l+a+++d++++ dl+sl phf+ l++++lel+++ d+++ +l d+++ R+++i ++a n  +a+
  EEA20310.1  44 VDLPLWLGEMLSigarlgTSRLVTLDLPSALSERVLNALKADPRTV-DLRSLAPHFYSLGIRVLELFEE-DNMADILSDTFRRRASEIADHAHNSRGAL 140
                 58********************************************.*********************9.***************************** PP

                 HTS-TCCHCCS-HHHH CS
        Sld5  94 gggggellsglseeEk 109
                  g+g e+l+gl+e E+
  EEA20310.1 141 -GEGVEFLRGLDETER 155
                 .9***********996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (179 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       232  (0.0129399); expected 358.6 (0.02)
Passed bias filter:                      222  (0.0123822); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.24s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 1324.53
//
Query:       EEA20311.1  [L=135]
Description: GINS complex subunit Psf3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.8e-14   51.9   0.0    1.3e-13   51.4   0.0    1.2  1  Sld5      GINS complex protein


Domain annotation for each model (and alignments):
>> Sld5  GINS complex protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.4   0.0   7.1e-18   1.3e-13       1      73 [.      44     120 ..      44     124 .. 0.96

  Alignments for each domain:
  == domain 1  score: 51.4 bits;  conditional E-value: 7.1e-18
                 EEEEHHHHHHHH......HTTSCCCHHCHHHCHHHHHHCCCHHTTSSSSTTTTTTHHHHHHHHHHHHT.HCHHHHHHHH CS
        Sld5   1 veLPlWlaelLk......rqrrveieppewlspesleailedetkssdlpslpphflelavkllelardldelkrllrd 73 
                 v+LPlWl e+L+       +r v++++p  ls+++l+a+++d++++ dl+sl phf+ l++++lel+++ d+++ +l d
  EEA20311.1  44 VDLPLWLGEMLSigarlgTSRLVTLDLPSALSERVLNALKADPRTV-DLRSLAPHFYSLGIRVLELFEE-DNMADILSD 120
                 58********************************************.*********************9.999988877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (135 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       160  (0.00892409); expected 358.6 (0.02)
Passed bias filter:                      153  (0.00853366); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.37u 0.26s 00:00:00.63 Elapsed: 00:00:00.40
# Mc/sec: 1010.71
//
Query:       EEA20312.1  [L=169]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.1e-08   34.6   0.0    1.3e-08   34.4   0.0    1.1  1  PNP_UDP_1  Phosphorylase superfamily


Domain annotation for each model (and alignments):
>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.4   0.0     7e-13   1.3e-08      29     108 ..      50     136 ..      22     159 .. 0.73

  Alignments for each domain:
  == domain 1  score: 34.4 bits;  conditional E-value: 7e-13
                 .TTEEEEEEEETTEEEEEE.E--SSHHHHHHHHHHHHHHHC.--SEEEEEEEEEES.....STTT-TT-EEEEEEEEESSSCCG.CCT CS
   PNP_UDP_1  29 grgfkfvtGtlkgkpvviv.stGiGkpnaavvaeirllkef.gvkaiiriGtaGgl.....npdlkvGDvvipddainfdgrsp.lyg 108
                 g    ++ G+++++ vv++ + G+Gk+naa +a+  +   f + k ++ +G++Gg+     ++++ +GDv+i ++++++d++++ + g
  EEA20312.1  50 GDLNSYTKGSIGQHGVVLAhLPGMGKVNAA-TAASTFKSTFrNLKLVLLVGICGGVpeganREQIVLGDVIIGTSVVQTDFGRQtPSG 136
                 55667788888666666552677*******.8888888888899************7777666688************7776652333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (169 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       202  (0.0112667); expected 358.6 (0.02)
Passed bias filter:                      182  (0.0101512); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.35u 0.22s 00:00:00.56 Elapsed: 00:00:00.35
# Mc/sec: 1440.71
//
Query:       EEA20313.1  [L=1166]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.7e-40  136.8   6.0    8.7e-11   42.3   0.0    6.5  6  Ank_2           Ankyrin repeats (3 copies)
    7.8e-33  112.4   3.9    8.8e-09   35.7   0.0    8.2  8  Ank_4           Ankyrin repeats (many copies)
    4.3e-29   97.3   2.0     0.0036   17.7   0.0   10.2  9  Ank_3           Ankyrin repeat
    1.7e-26   91.4  10.6     0.0036   17.7   0.0   10.1 10  Ank             Ankyrin repeat
    2.5e-20   72.3   1.7    0.00012   22.3   0.0    7.9  8  Ank_5           Ankyrin repeats (many copies)
    1.7e-07   31.3   0.1    4.5e-07   29.9   0.0    1.8  1  NACHT           NACHT domain
    0.00034   20.9   0.0     0.0008   19.7   0.0    1.6  1  AAA_22          AAA domain
    0.00078   18.8   1.2       0.43    9.8   0.1    2.3  2  KAP_NTPase      KAP family P-loop domain
     0.0012   18.6   0.0     0.0025   17.6   0.0    1.4  1  AAA_30          AAA domain
     0.0019   18.6   0.0     0.0053   17.2   0.0    1.7  1  AAA_16          AAA ATPase domain
     0.0063   16.9   0.0      0.016   15.6   0.0    1.7  1  RNA_helicase    RNA helicase
     0.0092   16.0   0.0      0.033   14.2   0.0    2.0  1  AAA_5           AAA domain (dynein-related subfamily)
  ------ inclusion threshold ------
      0.012   16.1   0.0      0.035   14.6   0.0    1.8  1  ABC_tran        ABC transporter
      0.023   14.6   0.0      0.065   13.1   0.0    1.7  1  Ploopntkinase3  P-loop Nucleotide Kinase3
      0.062   13.7   0.0       0.14   12.6   0.0    1.6  1  AAA             ATPase family associated with various cellula
      0.064   13.8   0.0        0.2   12.2   0.0    1.9  1  AAA_18          AAA domain
      0.076   12.9   0.0       0.28   11.0   0.0    2.0  1  APS_kinase      Adenylylsulphate kinase
       0.13   12.1   0.0       0.75    9.5   0.0    2.1  2  AAA_11          AAA domain
       0.14   11.9   0.0       0.37   10.6   0.0    1.7  1  AAA_29          P-loop containing region of AAA domain
       0.17   11.1   0.2       0.56    9.4   0.0    1.9  2  NB-ARC          NB-ARC domain
        1.1    9.8   3.5        2.4    8.7   0.2    3.2  3  DUF1843         Domain of unknown function (DUF1843)


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.1   9.6e-06    0.0082      11      82 ..     555     637 ..     545     638 .. 0.77
   2 !   32.1   0.2   1.5e-10   1.3e-07       3      81 ..     613     702 ..     612     703 .. 0.83
   3 !    7.7   0.0    0.0061       5.2      56      81 ..     746     771 ..     732     773 .. 0.85
   4 !   42.3   0.0     1e-13   8.7e-11      25      83 .]     798     862 ..     777     862 .. 0.86
   5 !   20.1   0.2   8.2e-07    0.0007      24      49 ..     863     890 ..     859     907 .. 0.79
   6 !   24.1   0.0   4.9e-08   4.2e-05      27      73 ..    1098    1149 ..    1085    1158 .. 0.80

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 9.6e-06
       Ank_2  11 elvklLlegadpn...k...ngktaLhyAakngnlei.vklLleh.ad...ndgr..tpLhyAarsghleivklLlekgadinlk 82 
                 +l++  l g+d++   +   + ++aL++A+k+ + ei  k+L+e+ a+   n g+  t+L++A    +  +v   +ekg d+n++
  EEA20313.1 555 NLFEVALRGSDVDintQggiF-NNALQLAVKKRD-EIsTKMLIEFgANvhiNGGYfgTVLQAALALENHSLVSTIIEKGTDLNAT 637
                 377777877666653434544.69*******987.7768*****88555676777779******99777*************985 PP

  == domain 2  score: 32.1 bits;  conditional E-value: 1.5e-10
       Ank_2   3 lAakn.gnlelvklLl.egadpn.k...ngktaLhyAakngnleivklLleh...ad....ndgrtpLhyAarsghleivklLlekgadinl 81 
                 +Aa+  +n++lv  ++ +g+d+n +   +g t+L++Aa +gnl+++k Lle    ++     +g ++Lh+A+ s+  ei++ Ll  gad+n 
  EEA20313.1 613 QAALAlENHSLVSTIIeKGTDLNaTggvFG-TVLQAAAARGNLQVLKSLLERsaeVNvdggIYG-SVLHAAIGSQKVEIFQQLLHAGADVNS 702
                 5666446678************97357898.*******************96667553255445.6******************88****95 PP

  == domain 3  score: 7.7 bits;  conditional E-value: 0.0061
       Ank_2  56 pLhyAars.ghleivklLlekgadinl 81 
                 ++ +Aars  + + vklLle+gad+n+
  EEA20313.1 746 AIVWAARSlEN-DQVKLLLENGADVNA 771
                 67899*99655.*************97 PP

  == domain 4  score: 42.3 bits;  conditional E-value: 1e-13
       Ank_2  25 ngktaLhyAakngnleivklLleh.ad.....ndgrtpLhyAarsghleivklLlekgadinlkd 83 
                  g+taL++Aa++g +++++lL+eh ad     ++g+t+L + ++ gh eivk+L+++ga++ +kd
  EEA20313.1 798 LGMTALIWAARRGMRDMIELLMEHgADieahsSSGETALLAGSEAGHKEIVKFLIDRGANLSAKD 862
                 79*********************99555566899**************************99987 PP

  == domain 5  score: 20.1 bits;  conditional E-value: 8.2e-07
       Ank_2  24 kngktaLhyAakngnleivklLleh..a 49 
                 ++g+taL+ Aa ng+++i++lLl+h  +
  EEA20313.1 863 SFGQTALYKAAANGHVDIMRLLLKHedF 890
                 389********************98552 PP

  == domain 6  score: 24.1 bits;  conditional E-value: 4.9e-08
       Ank_2   27 ktaLhyAakngnleivklLleh...ad..ndgrtpLhyAarsghleivklLl 73  
                   ++L++Aa+ng+l++v+lLle    +d  +  ++pLh+A + g+ +iv lL 
  EEA20313.1 1098 PSPLYVAAQNGHLQAVQLLLESganFDkeSPVMNPLHVARQRGYNRIVGLLK 1149
                  589*****************977443343446799****9889999998885 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.098        84      20      55 .]     561     595 ..     548     595 .. 0.86
   2 !   19.7   0.0   1.1e-06   0.00091       3      54 ..     610     660 ..     609     661 .. 0.89
   3 !   18.1   0.0   3.6e-06     0.003       3      52 ..     643     691 ..     642     694 .. 0.86
   4 ?    3.2   0.0      0.16   1.4e+02       3      28 ..     676     701 ..     674     702 .. 0.90
   5 !    7.7   0.0    0.0064       5.5       4      30 ..     746     772 ..     743     783 .. 0.84
   6 !   32.9   0.0     8e-11   6.9e-08       1      55 []     799     852 ..     799     852 .. 0.98
   7 !   35.7   0.0     1e-11   8.8e-09      10      55 .]     841     885 ..     837     885 .. 0.95
   8 !   13.6   0.0     9e-05     0.076       3      47 ..    1099    1141 ..    1097    1150 .. 0.78

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.098
       Ank_4  20 LlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 L  +++din q  +  ++al+ A+k+ +   +k+L+
  EEA20313.1 561 LRGSDVDINTQ-GGIFNNALQLAVKKRDEISTKMLI 595
                 456889*****.888889********9988888886 PP

  == domain 2  score: 19.7 bits;  conditional E-value: 1.1e-06
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54 
                 t+L +a + +++ lv  ++ekg d+na+  +   t l+ Aa rgn+++lk L
  EEA20313.1 610 TVLQAALALENHSLVSTIIEKGTDLNAT-GGVFGTVLQAAAARGNLQVLKSL 660
                 78999999********************.44455***************966 PP

  == domain 3  score: 18.1 bits;  conditional E-value: 3.6e-06
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGe.talhiAakrgnveilk 52 
                 t+L +aa+ g+l+++++Lle+ a++n   ++    + lh A+   +vei++
  EEA20313.1 643 TVLQAAAARGNLQVLKSLLERSAEVNV--DGGIYgSVLHAAIGSQKVEIFQ 691
                 79999********************99..6554458999999999999987 PP

  == domain 4  score: 3.2 bits;  conditional E-value: 0.16
       Ank_4   3 taLhyaaisgrlelvrlLlekgadin 28 
                 ++Lh+a+ s+++e+ + Ll  gad+n
  EEA20313.1 676 SVLHAAIGSQKVEIFQQLLHAGADVN 701
                 89**************99989***99 PP

  == domain 5  score: 7.7 bits;  conditional E-value: 0.0064
       Ank_4   4 aLhyaaisgrlelvrlLlekgadinaq 30 
                 a+ +aa s   + v+lLle+gad+na 
  EEA20313.1 746 AIVWAARSLENDQVKLLLENGADVNAA 772
                 6677777777889************85 PP

  == domain 6  score: 32.9 bits;  conditional E-value: 8e-11
       Ank_4   1 eltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++taL +aa  g  ++++lL e+gadi a  ++sGetal  +   g++ei+k+L+
  EEA20313.1 799 GMTALIWAARRGMRDMIELLMEHGADIEAH-SSSGETALLAGSEAGHKEIVKFLI 852
                 69***************************8.***********************8 PP

  == domain 7  score: 35.7 bits;  conditional E-value: 1e-11
       Ank_4  10 isgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++g+ e+v++L+++ga++ a  ++ G+tal++Aa +g+v+i +lLl
  EEA20313.1 841 EAGHKEIVKFLIDRGANLSAK-DSFGQTALYKAAANGHVDIMRLLL 885
                 489*****************9.**********************98 PP

  == domain 8  score: 13.6 bits;  conditional E-value: 9e-05
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgn 47  
                  ++L  aa+ g+l++v+lLle+ga+ ++ ++   +++lh A +rg+
  EEA20313.1 1099 SPLYVAAQNGHLQAVQLLLESGANFDKESP--VMNPLHVARQRGY 1141
                  6889999****************9887433..4777777766665 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0      0.18   1.5e+02       4      31 .]     577     603 ..     576     603 .. 0.85
   2 ?    3.4   0.0      0.19   1.6e+02       4      31 .]     610     636 ..     609     636 .. 0.91
   3 ?    6.5   0.0     0.018        16       4      30 ..     643     668 ..     642     669 .. 0.93
   4 !    9.2   0.0    0.0023         2       4      30 ..     676     701 ..     674     702 .. 0.95
   5 ?    5.7   0.0     0.033        29      16      31 .]     758     771 ..     742     771 .. 0.76
   6 !   17.7   0.0   4.2e-06    0.0036       2      30 ..     799     826 ..     798     827 .. 0.94
   7 !   11.6   0.0   0.00041      0.35       2      30 ..     832     859 ..     831     860 .. 0.93
   8 !   15.4   0.0   2.3e-05      0.02       2      24 ..     865     887 ..     864     891 .. 0.91
   9 !   11.7   0.0   0.00036      0.31       4      30 ..    1099    1124 ..    1098    1125 .. 0.93

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.18
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadvna 31 
                 ++L lA++  +    k+L+e +ga+v++
  EEA20313.1 577 NALQLAVKKRDEISTKMLIE-FGANVHI 603
                 688899999998669*****.****986 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.19
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadvna 31 
                 t L  A+   n+++v  ++e kg d+na
  EEA20313.1 610 TVLQAALALENHSLVSTIIE-KGTDLNA 636
                 7788899999999*******.9****96 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.018
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadvn 30 
                 t L  Aa  gnl ++k Lle + a+vn
  EEA20313.1 643 TVLQAAAARGNLQVLKSLLE-RSAEVN 668
                 78999***************.9**999 PP

  == domain 4  score: 9.2 bits;  conditional E-value: 0.0023
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadvn 30 
                 + Lh A+ s+++ei + Ll   gadvn
  EEA20313.1 676 SVLHAAIGSQKVEIFQQLLH-AGADVN 701
                 68******************.9****9 PP

  == domain 5  score: 5.7 bits;  conditional E-value: 0.033
       Ank_3  16 eivkfLlenkgadvna 31 
                   vk+Lle +gadvna
  EEA20313.1 758 Q-VKLLLE-NGADVNA 771
                 4.9*****.8****96 PP

  == domain 6  score: 17.7 bits;  conditional E-value: 4.2e-06
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G+t+L +Aar g  +++++L e +gad+ 
  EEA20313.1 799 GMTALIWAARRGMRDMIELLME-HGADIE 826
                 89********************.9***96 PP

  == domain 7  score: 11.6 bits;  conditional E-value: 0.00041
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 Get+L    ++g+ eivkfL++ +ga++ 
  EEA20313.1 832 GETALLAGSEAGHKEIVKFLID-RGANLS 859
                 99********************.9**986 PP

  == domain 8  score: 15.4 bits;  conditional E-value: 2.3e-05
       Ank_3   2 GetpLhlAarsgnleivkfLlen 24 
                 G+t+L+ Aa +g+++i+++Ll++
  EEA20313.1 865 GQTALYKAAANGHVDIMRLLLKH 887
                 9********************94 PP

  == domain 9  score: 11.7 bits;  conditional E-value: 0.00036
       Ank_3    4 tpLhlAarsgnleivkfLlenkgadvn 30  
                  +pL++Aa +g+l  v++Lle  ga+++
  EEA20313.1 1099 SPLYVAAQNGHLQAVQLLLE-SGANFD 1124
                  79******************.899986 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0      0.97   8.3e+02       5      28 ..     578     602 ..     576     604 .. 0.73
   2 ?   -0.3   0.1         2   1.7e+03       9      30 ..     615     637 ..     610     638 .. 0.75
   3 !    7.2   0.0    0.0089       7.6       4      29 ..     643     669 ..     643     671 .. 0.87
   4 !   10.1   0.0    0.0011      0.92       5      30 ..     677     703 ..     676     704 .. 0.85
   5 ?    6.4   0.1     0.015        13      17      29 ..     758     771 ..     746     773 .. 0.82
   6 !   17.7   0.0   4.2e-06    0.0036       2      31 ..     799     829 ..     798     830 .. 0.86
   7 !   16.7   0.0   8.9e-06    0.0076       2      31 ..     832     862 ..     831     863 .. 0.88
   8 !    9.7   0.1    0.0014       1.2       2      23 ..     865     887 ..     864     894 .. 0.88
   9 !   14.4   0.0   4.5e-05     0.038       4      26 ..    1099    1122 ..    1099    1126 .. 0.93
  10 ?    3.0   0.0      0.18   1.6e+02       4      21 ..    1131    1148 ..    1130    1154 .. 0.84

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.97
                 HHHHHHHHTTHHHHHHHH.TTTSTT CS
         Ank   5 PLHlAatngkkriiklLL.hGAnln 28 
                 +L lA+   ++  +k+L+  GAn++
  EEA20313.1 578 ALQLAVKKRDEISTKMLIeFGANVH 602
                 7788884444667899**88***97 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 2
                 HHHHTTHHHHHHHH.TTTSTTCB CS
         Ank   9 AatngkkriiklLL.hGAnlnal 30 
                 A    +++ ++ ++ +G +lna+
  EEA20313.1 615 ALALENHSLVSTIIeKGTDLNAT 637
                 4445677899999*99*****97 PP

  == domain 3  score: 7.2 bits;  conditional E-value: 0.0089
                 BHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnlna 29 
                 T+L  Aa +g+++++k LL ++A++n 
  EEA20313.1 643 TVLQAAAARGNLQVLKSLLeRSAEVNV 669
                 788888889**********77899995 PP

  == domain 4  score: 10.1 bits;  conditional E-value: 0.0011
                 HHHHHHHHTTHHHHHHHHT.TTSTTCB CS
         Ank   5 PLHlAatngkkriiklLLh.GAnlnal 30 
                 +LH A+   k++i + LLh GA++n++
  EEA20313.1 677 VLHAAIGSQKVEIFQQLLHaGADVNSH 703
                 79**995566********76*****97 PP

  == domain 5  score: 6.4 bits;  conditional E-value: 0.015
                 HHHHHH.TTTSTTC CS
         Ank  17 iiklLL.hGAnlna 29 
                  +klLL +GA++na
  EEA20313.1 758 QVKLLLeNGADVNA 771
                 69****99*****9 PP

  == domain 6  score: 17.7 bits;  conditional E-value: 4.2e-06
                 SBBHHHHHH...HHTTHHHHHHHH.TTTSTTCBT CS
         Ank   2 GnTPLHlAa...tngkkriiklLL.hGAnlnald 31 
                 G+T+L +Aa   +++   +i+lL  hGA++ a+ 
  EEA20313.1 799 GMTALIWAArrgMRD---MIELLMeHGADIEAHS 829
                 9********555555...***999******9986 PP

  == domain 7  score: 16.7 bits;  conditional E-value: 8.9e-06
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlnald 31 
                 G T+L   +  g+k+i+k+L+ +GAnl a+d
  EEA20313.1 832 GETALLAGSEAGHKEIVKFLIdRGANLSAKD 862
                 77888888899**********779******9 PP

  == domain 8  score: 9.7 bits;  conditional E-value: 0.0014
                 SBBHHHHHHHHTTHHHHHHHH.T CS
         Ank   2 GnTPLHlAatngkkriiklLL.h 23 
                 G T+L  Aa ng+++i +lLL h
  EEA20313.1 865 GQTALYKAAANGHVDIMRLLLkH 887
                 99****8887***********76 PP

  == domain 9  score: 14.4 bits;  conditional E-value: 4.5e-05
                  BHHHHHHHHTTHHHHHHHH.TTTS CS
         Ank    4 TPLHlAatngkkriiklLL.hGAn 26  
                  +PL +Aa+ng+++ ++lLL +GAn
  EEA20313.1 1099 SPLYVAAQNGHLQAVQLLLeSGAN 1122
                  6******************99**9 PP

  == domain 10  score: 3.0 bits;  conditional E-value: 0.18
                  BHHHHHHHHTTHHHHHHH CS
         Ank    4 TPLHlAatngkkriiklL 21  
                   PLH+A ++g  ri+ lL
  EEA20313.1 1131 NPLHVARQRGYNRIVGLL 1148
                  6****99999999**976 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.0      0.33   2.9e+02       5      44 ..     563     603 ..     560     613 .. 0.86
   2 ?    3.6   0.0      0.11        91      17      44 ..     640     669 ..     627     672 .. 0.78
   3 ?    2.5   0.0      0.22   1.9e+02      16      55 ..     675     713 ..     665     713 .. 0.86
   4 ?   -0.8   0.0       2.4     2e+03      32      44 ..     759     771 ..     756     774 .. 0.79
   5 !   22.3   0.0   1.4e-07   0.00012      15      53 ..     798     836 ..     793     837 .. 0.95
   6 !   22.1   0.0   1.6e-07   0.00014       1      38 [.     851     887 ..     842     893 .. 0.95
   7 !    9.1   0.0     0.002       1.7      18      41 ..    1099    1122 ..    1087    1128 .. 0.88
   8 ?   -1.4   0.0       3.8   3.2e+03      17      32 ..    1130    1145 ..    1129    1148 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.33
       Ank_5   5 g.padvnrldgggntpLhvAakygaadvvrlLlargadlnl 44 
                 g ++d+n++ g  n++L +A+k++     ++L+++ga+  +
  EEA20313.1 563 GsDVDINTQGGIFNNALQLAVKKRDEISTKMLIEFGANVHI 603
                 76899999999999***********9999999999988765 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.11
       Ank_5  17 n..tpLhvAakygaadvvrlLlargadlnl 44 
                 +  t+L  Aa +g+++v++ Ll+r a  n+
  EEA20313.1 640 VfgTVLQAAAARGNLQVLKSLLERSAEVNV 669
                 44499999**************88777665 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.22
       Ank_5  16 gntpLhvAakygaadvvrlLlargadlnltdsrGltaldl 55 
                 g ++Lh A+  +  ++++ Ll  gad n   + + +aldl
  EEA20313.1 675 G-SVLHAAIGSQKVEIFQQLLHAGADVNSHGGIYGSALDL 713
                 4.89*****************9999999888888888875 PP

  == domain 4  score: -0.8 bits;  conditional E-value: 2.4
       Ank_5  32 vrlLlargadlnl 44 
                 v+lLl++gad n+
  EEA20313.1 759 VKLLLENGADVNA 771
                 6778899999886 PP

  == domain 5  score: 22.3 bits;  conditional E-value: 1.4e-07
       Ank_5  15 ggntpLhvAakygaadvvrlLlargadlnltdsrGltal 53 
                  g+t+L++Aa++g  d+++lL+++gad+ +  s+G+tal
  EEA20313.1 798 LGMTALIWAARRGMRDMIELLMEHGADIEAHSSSGETAL 836
                 69***********************************98 PP

  == domain 6  score: 22.1 bits;  conditional E-value: 1.6e-07
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlar 38 
                 L+++g a++ ++d +g+t+L  Aa +g+ d++rlLl++
  EEA20313.1 851 LIDRG-ANLSAKDSFGQTALYKAAANGHVDIMRLLLKH 887
                 89999.******************************65 PP

  == domain 7  score: 9.1 bits;  conditional E-value: 0.002
       Ank_5   18 tpLhvAakygaadvvrlLlargad 41  
                  +pL vAa +g+++ v+lLl+ ga+
  EEA20313.1 1099 SPLYVAAQNGHLQAVQLLLESGAN 1122
                  69*****************65554 PP

  == domain 8  score: -1.4 bits;  conditional E-value: 3.8
       Ank_5   17 ntpLhvAakygaadvv 32  
                  ++pLhvA  +g+ ++v
  EEA20313.1 1130 MNPLHVARQRGYNRIV 1145
                  69*****888887776 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.9   0.0   5.3e-10   4.5e-07       2     110 ..      96     223 ..      95     279 .. 0.80

  Alignments for each domain:
  == domain 1  score: 29.9 bits;  conditional E-value: 5.3e-10
                 CEEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-...-HCHHHCCCCTS--SSS-CCHHHHCCSCCCEE................ CS
       NACHT   2 lvilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgnarsladllfsqlpepaapvsevwavllelperlL................ 84 
                 + +l+G++GsGK+t+++++ ++++++++    + l  f++ r    ++++++l + l+ ql+ ++ +  + ++++ + ++  L                
  EEA20313.1  96 VFWLKGKPGSGKSTMMRHISHQLQKSHDS---VLLEHFFNARGSGLEKTFLGLLRSLVFQLLNEIPEFCPTFILIYRKKNLNLgqwewrqselrnflqs 191
                 579************************44...5899999999999998889999999999999999999978888888887789999999999999999 PP

                 ..........EEEE-STT-SS-TCH.........HH CS
       NACHT  85 ..........lilDglDelvtdlgqkekqpvrtlLs 110
                           +++D+lDe++ d      ++v   L+
  EEA20313.1 192 klksyereltILVDALDECSFDEI----TSVVSFLE 223
                 9999999999*********96433....34444444 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.0   9.3e-07    0.0008       5     118 ..      94     224 ..      90     245 .. 0.76

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 9.3e-07
      AAA_22   5 agilvvtGesGtGKTtllrrlleqldeeakaeeerpevv...fvtlpsst...sskdllrellralglelka..................erlsseell 79 
                  g+  + G +G+GK+t +r + +ql++       +++v+   f+++ +s+   +   llr l+ +l +e  +                   + +++el+
  EEA20313.1  94 NGVFWLKGKPGSGKSTMMRHISHQLQKS------HDSVLlehFFNARGSGlekTFLGLLRSLVFQLLNEIPEfcptfiliyrkknlnlgqWEWRQSELR 186
                 6677789******************865......888888**********66666666555555555555558999*******9999998777889999 PP

      AAA_22  80 ealeqalraravielliiDEaqhlrseealeeLrsllnl 118
                 + l+  l+++ +   +++D  +   s + ++ ++s+l++
  EEA20313.1 187 NFLQSKLKSYERELTILVDALDEC-SFDEITSVVSFLED 224
                 999999999999888888988887.65555555555544 PP

>> KAP_NTPase  KAP family P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.8   0.1    0.0005      0.43      22      79 ..      96     151 ..      87     183 .. 0.79
   2 !    7.5   0.1    0.0024       2.1     159     195 ..     184     220 ..     179     226 .. 0.88

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.0005
  KAP_NTPase  22 vvgLygkWGsGKssllnkledelkefakpvrflfaefnawsfkggddavaellaaLad 79 
                 v+ L+gk GsGKs++   + ++l++    +++l   f  +  +g ++ +  ll++L+ 
  EEA20313.1  96 VFWLKGKPGSGKSTMMRHISHQLQKS--HDSVLLEHFFNARGSGLEKTFLGLLRSLVF 151
                 899**********************9..888888877777777777777777777754 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0024
  KAP_NTPase 159 elladmektLdalqkrlVvviDdLDrceteevlqlle 195
                 el++ ++++L+  +++l +++D+LD c  +e++++  
  EEA20313.1 184 ELRNFLQSKLKSYERELTILVDALDECSFDEITSVVS 220
                 5889999**********************99998865 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   2.9e-06    0.0025      11      49 ..      88     125 ..      80     132 .. 0.80

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 2.9e-06
      AAA_30  11 ealltsgdrvavltGpAGtGKttalkalreaweaaggrv 49 
                  +l++s+  v  l+G +G+GK+t+++++ + ++++  +v
  EEA20313.1  88 SNLTESN-GVFWLKGKPGSGKSTMMRHISHQLQKSHDSV 125
                 4555555.6*******************99998886665 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   6.2e-06    0.0053      25     146 ..      95     209 ..      81     237 .. 0.59

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 6.2e-06
      AAA_16  25 elvllsGesGvGKsslvrellralekdg.giflrgkcdqlesaipysa.laqalareellrqllde.............aesaeleawrekleealaav 108
                 ++  l G +G+GKs+++r++ ++l+k++  ++l+  +   +s+++    ++ +l r +l+ qll+e             +                   
  EEA20313.1  95 GVFWLKGKPGSGKSTMMRHISHQLQKSHdSVLLEHFFNARGSGLE--KtFLGLL-R-SLVFQLLNEipefcptfiliyrK------------------- 170
                 667899*********************845555555555555532..2244444.4.55555555533333333333332................... PP

      AAA_16 109 pelagaeasrllellkrll.allsrderplvlvlDdlqw 146
                 ++l   + +    +l+++l ++l++ er l +++D l+ 
  EEA20313.1 171 KNLNLGQWEWRQSELRNFLqSKLKSYERELTILVDALDE 209
                 222222223334444444444444445556666666664 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   1.8e-05     0.016       2      26 ..      98     122 ..      97     140 .. 0.85

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 1.8e-05
  RNA_helicase   2 wlyGpsgeGKStlakeLakallkkl 26 
                   wl G++g GKSt++++++++l+k+ 
    EEA20313.1  98 WLKGKPGSGKSTMMRHISHQLQKSH 122
                   9*****************9999766 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.0   3.9e-05     0.033       4      33 ..      99     128 ..      96     134 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 3.9e-05
                 EE--SSSSHHHHHHHGGGGBS--EEEEE-- CS
       AAA_5   4 LvGppGtgKselaerlaaalnreveyvqlt 33 
                 L+G+pG+gKs++++++++ l+++   v+l 
  EEA20313.1  99 LKGKPGSGKSTMMRHISHQLQKSHDSVLLE 128
                 9*******************9887777766 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.0   4.1e-05     0.035      15      45 ..      98     128 ..      88     237 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 4.1e-05
                 EEEESTTSSHHHHHHHHTTSS--SEEEEEET CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  15 aivGenGaGKStLlkllagllkpteGeilld 45 
                  + G+ G+GKSt+++ ++++l++  +++ll+
  EEA20313.1  98 WLKGKPGSGKSTMMRHISHQLQKSHDSVLLE 128
                 678*********************9999554 PP

>> Ploopntkinase3  P-loop Nucleotide Kinase3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   7.6e-05     0.065       6      31 ..      97     122 ..      93     132 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 7.6e-05
  Ploopntkinase3   6 iylvGqPGaGkstlmaeltkgfdrsk 31 
                      +l G+PG+Gkst+m ++++ +++s+
      EEA20313.1  97 FWLKGKPGSGKSTMMRHISHQLQKSH 122
                     6899***************9999876 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   0.00016      0.14       3      63 ..      99     166 ..      97     208 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 0.00016
                 EESSTTSSHHHHHHHHHHHHT........HEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEE CS
         AAA   3 lyGppGtGKTllakavakelg........vefleisgsellskyvgesekkirelfkeakekakpsilf 63 
                 l G pG GK+++++ + ++l+         +f++  gs l + ++g   + + +l++e+ e   p+ ++
  EEA20313.1  99 LKGKPGSGKSTMMRHISHQLQkshdsvllEHFFNARGSGLEKTFLGLLRSLVFQLLNEIPEFC-PTFIL 166
                 78*****************964444455566**********9999998888888888876654.55555 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00023       0.2       3      25 ..      99     137 ..      98     214 .. 0.65

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00023
      AAA_18   3 ltGtpGvGKttlakeLskrl.gf...............g 25 
                 l G+pG+GK+t+ +++s  l ++               g
  EEA20313.1  99 LKGKPGSGKSTMMRHISHQLqKShdsvllehffnargsG 137
                 77**************98875556655444444444442 PP

>> APS_kinase  Adenylylsulphate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00033      0.28       4      33 ..      96     125 ..      93     134 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00033
                 EEEEESSTTSSHHHHHHHHHHHHHHTT--E CS
  APS_kinase   4 vvwltGlsgsGKstianalekkLvekgisv 33 
                 v+wl G  gsGKst+ ++++++L+++  sv
  EEA20313.1  96 VFWLKGKPGSGKSTMMRHISHQLQKSHDSV 125
                 79*********************9987655 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.0   0.00087      0.75       6      43 ..      83     120 ..      80     291 .. 0.88
   2 ?   -0.4   0.0      0.96   8.2e+02     176     203 ..     879     906 ..     808     909 .. 0.74

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00087
      AAA_11   6 qreaiksalseseitliqGPPGtgKTktivellsqlls 43 
                 q++  ++  ++++++ ++G+PG+gK+++  ++ +ql +
  EEA20313.1  83 QWRDRSNLTESNGVFWLKGKPGSGKSTMMRHISHQLQK 120
                 66666777888999*********************952 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.96
      AAA_11 176 elskeleeaeesleeevldeaeivltTl 203
                 ++ + l ++e+   +++ ++++++ +T+
  EEA20313.1 879 DIMRLLLKHEDFHDTHFCSDHDVITCTN 906
                 5555666777777899999999999997 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00044      0.37      21      39 ..      93     111 ..      82     119 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00044
      AAA_29  21 lkgatlltGpsGsGKSTll 39 
                  +g++ l G+ GsGKST++
  EEA20313.1  93 SNGVFWLKGKPGSGKSTMM 111
                 457999***********97 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.0   0.00065      0.56      22      51 ..      96     122 ..      86     130 .. 0.79
   2 ?   -2.5   0.1       2.7   2.3e+03      92     125 ..     181     219 ..     166     223 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00065
                 EEEEEESTTSSHHHHHHHHCCSHCCCCCCB CS
      NB-ARC  22 vvalvGmgGvGKttlakqilnksdevegrF 51 
                 v  l G++G+GK+t++++i ++   +++  
  EEA20313.1  96 VFWLKGKPGSGKSTMMRHISHQ---LQKSH 122
                 56799**************998...44444 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 2.7
                 HHHHHHHHCCCT.....TEEEEEEEE-SHHHH.....HH CS
      NB-ARC  92 lkrklvrlLltk.....rfllvlDDVweeedwdkigvvl 125
                 ++ +l+++L++k     r l +l D  +e  +d+i+ v+
  EEA20313.1 181 RQSELRNFLQSKlksyeRELTILVDALDECSFDEITSVV 219
                 677888888887777788999999999999999998765 PP

>> DUF1843  Domain of unknown function (DUF1843)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.2    0.0028       2.4       4      26 ..     642     664 ..     640     692 .. 0.79
   2 ?   -0.6   0.0       2.3     2e+03       2      24 ..     673     695 ..     672     708 .. 0.77
   3 ?   -1.3   0.0       3.7   3.2e+03       6      24 ..     868     886 ..     867     891 .. 0.85

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0028
     DUF1843   4 gvaiqqAiasGDLakMKalaaqa 26 
                 g  +q+A+a+G L+ +K+l+ + 
  EEA20313.1 642 GTVLQAAAARGNLQVLKSLLERS 664
                 6779***************9764 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 2.3
     DUF1843   2 lYgvaiqqAiasGDLakMKalaa 24 
                 +Yg  +++Ai s +++   +l+ 
  EEA20313.1 673 IYGSVLHAAIGSQKVEIFQQLLH 695
                 59999*****9988887777765 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 3.7
     DUF1843   6 aiqqAiasGDLakMKalaa 24 
                 a+ +A+a G ++ M+ l++
  EEA20313.1 868 ALYKAAANGHVDIMRLLLK 886
                 7889**********98886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1166 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       540  (0.0301188); expected 358.6 (0.02)
Passed bias filter:                      496  (0.0276647); expected 358.6 (0.02)
Passed Vit filter:                        82  (0.0045736); expected 17.9 (0.001)
Passed Fwd filter:                        21  (0.00117129); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              21  [number of targets reported over threshold]
# CPU time: 0.91u 0.32s 00:00:01.23 Elapsed: 00:00:00.51
# Mc/sec: 6919.85
//
Query:       EEA20314.1  [L=1685]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.7e-38  131.6   0.2    7.3e-38  130.6   0.2    1.5  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    2.4e-07   30.5   0.0    5.7e-07   29.3   0.0    1.6  1  gag_pre-integrs  GAG-pre-integrase domain
    0.00069   19.8   0.0     0.0016   18.6   0.0    1.6  1  rve              Integrase core domain
  ------ inclusion threshold ------
      0.029   13.9   0.0      0.061   12.8   0.0    1.5  1  RVT_1            Reverse transcriptase (RNA-dependent DNA pol
       0.09   12.7   0.0       0.21   11.5   0.0    1.6  1  Flg_hook         Flagellar hook-length control protein FliK
       0.14   12.5   3.2       0.37   11.1   3.2    1.7  1  Orthopox_F14     Orthopoxvirus F14 protein


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  130.6   0.2   2.5e-41   7.3e-38       9     234 ..    1189    1411 ..    1180    1417 .. 0.91

  Alignments for each domain:
  == domain 1  score: 130.6 bits;  conditional E-value: 2.5e-41
       RVT_2    9 PkdrkaigsrWvftkkkddl.kevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeeelvvhqldvdsafLnaeldeevyvkqPpGfe 104 
                   k+++ +   W++  k+d++ + vk karlv++G  q    d  +++a  +   s r ++a+aa  +l + q d   af+na+ldee++++  pG+ 
  EEA20314.1 1189 AKGKQILDCMWIYVYKQDKKgRLVKCKARLVVRG-DQEKRDDMRDTYAATLAARSFRTFMAIAARFDLELKQYDAVNAFVNAKLDEEIFMRMAPGYR 1284
                  577888999********999899***********.577889******************************************************96 PP

       RVT_2  105 idreeekvykLnkslyGlkqapllWnekidkvLkklgferseaesGlyvrgtgegklivalyvddlliagsdikil..edvkkelakkfklkdlgkv 199 
                     e++k+y+Lnk+lyGl+++pllW+++++++L klgf+  + e    +++     +++  yvdd+++a ++++ l  + + ++l +k++++   ++
  EEA20314.1 1285 ---ESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFRAVPHEPCCMLKS----GVMLFFYVDDIVVAYKKSRQLeaNSILNQLRAKYNISGGEDL 1374
                  ...46****************************************999999....78999*********9999877225799*************** PP

       RVT_2  200 skfLGieiaq..eaggiklsladyiakvvkkfeltda 234 
                  + fLG+ i++  ++  i ls+a yi k++k ++ ++a
  EEA20314.1 1375 EWFLGMRIIRdrSNKMIWLSQATYIDKIAKLADTQQA 1411
                  ********986568889***********998876655 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.3   0.0   1.9e-10   5.7e-07      19      66 ..     558     609 ..     541     610 .. 0.76

  Alignments for each domain:
  == domain 1  score: 29.3 bits;  conditional E-value: 1.9e-10
  gag_pre-integrs  19 knkssinlWHrRLGHpsfsrlkkLfkkgl...lpglkisk.sevCeaCqlgK 66 
                        k ++n+WH RLGHp+ + lk+L+       l g++++    +Ce+C  +K
       EEA20314.1 558 ERKADANRWHARLGHPGPEVLKHLAGAAKgvrLTGISKGPtTVECESCGTSK 609
                      35899********************8544334555554433559****9988 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0   5.3e-07    0.0016       2     116 ..     623     739 ..     622     741 .. 0.86

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 5.3e-07
         rve   2 trpgelwqvDvtvvripdgggkayllvvvddfsrlilaealsdemdastvlalleravarfggve...pervlsDngseytskafrefla.dlgirvsf 96 
                 ++pge++ +D+  ++ ++  g++ l  ++d fs++++ ++++++   + +l++l+ +++++ +     p ++ +Dn  + +  +++ +l+ + +i +++
  EEA20314.1 623 HAPGEHLAIDFHDFAESTMHGEKTLMLITDRFSGFMWDYYMTSH-RGDEILETLKWFLDYLEKAYmisPVKIEMDNEIAKRP-EVKHYLEhEKRIILQP 719
                 89**********777799999***********************.**********99999999879**********976664.5555555157899999 PP

         rve  97 trpgrpqdnGkvErfhrtlk 116
                 ++++    nG +Er   ++k
  EEA20314.1 720 SPAHTQALNGGAERSGAIIK 739
                 99999999999999876666 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0     2e-05     0.061     117     185 ..    1278    1360 ..    1249    1370 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 2e-05
                  .........TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T................TEEECTTEEEEEESSHHH..HHHHHH CS
       RVT_1  117 rv.nge.eskgryekkglpqGsvlSPllfnlfmnellrelrkra..........kgvtllrYaDDililskskee..lqelle 185 
                  r+  g  es+++y+ +    G+  SPll++  +++ l +l  ra          +gv l  Y+DDi++++k+  +  ++++l+
  EEA20314.1 1278 RMaPGYrESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFRAvphepccmlkSGVMLFFYVDDIVVAYKKSRQleANSILN 1360
                  44344447899999999999***************9999999999***************************88844444454 PP

>> Flg_hook  Flagellar hook-length control protein FliK
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   7.2e-05      0.21      34      69 ..    1571    1606 ..    1563    1622 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 7.2e-05
                  ETTEEEEEEEE-SCHHHHHHHHTHHHHHHHHHCCTT CS
    Flg_hook   34 rggqlsvqltaenpetrelLeqnlprLreaLaaaGl 69  
                  r +  ++++  +n++t+ lLe+++prLr+ L+   +
  EEA20314.1 1571 RFQTPTLHVYCDNQQTLGLLEKDAPRLRTKLRHVDI 1606
                  55566899**********************987544 PP

>> Orthopox_F14  Orthopoxvirus F14 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   3.2   0.00012      0.37      32      70 ..     886     923 ..     875     926 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00012
  Orthopox_F14  32 idedditellniltelGcdvdfdedfsdiaddvleslie 70 
                   +  ++it ll  l +lG d dfd++++d+ d + + +++
    EEA20314.1 886 VSTQEITRLLTKL-DLGTDADFDDEYADLIDHITDVVFD 923
                   5667888888776.79***************99887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1685 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       978  (0.0545485); expected 358.6 (0.02)
Passed bias filter:                      648  (0.0361426); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.02u 0.30s 00:00:01.32 Elapsed: 00:00:00.46
# Mc/sec: 10918.85
//
Query:       EEA20315.1  [L=185]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
      0.066   12.4   0.1       0.15   11.3   0.1    1.5  1  PNP_UDP_1  Phosphorylase superfamily


Domain annotation for each model (and alignments):
>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   8.2e-06      0.15     138     203 ..      60     120 ..      41     144 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 8.2e-06
                 TTTTTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTB CS
   PNP_UDP_1 138 algikvhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArelgipfaairvvsdlaag 203
                  +++ +h G+va++d++  + ++++r+ +   + a eME+a +       ++p +++++vsd+a+ 
  EEA20315.1  60 HNEPSIHFGAVAASDSVMKSGTDRDRIAKAEKVIAFEMEAAGLWD-----QLPTLIVKGVSDYADC 120
                 345999*********************************997755.....6777777777775555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (185 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       609  (0.0339673); expected 358.6 (0.02)
Passed bias filter:                      330  (0.0184059); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.23s 00:00:00.66 Elapsed: 00:00:00.42
# Mc/sec: 1308.15
//
Query:       EEA20316.1  [L=114]
Description: hypothetical protein PMAA_041620 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (114 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       319  (0.0177924); expected 358.6 (0.02)
Passed bias filter:                      259  (0.0144459); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.36u 0.24s 00:00:00.60 Elapsed: 00:00:00.39
# Mc/sec: 887.02
//
Query:       EEA20317.1  [L=877]
Description: hypothetical protein PMAA_041630 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.2e-49  169.5   0.2      2e-49  168.8   0.2    1.3  1  DDE_Tnp_1_7  Transposase IS4
  ------ inclusion threshold ------
        0.1   12.7   0.2       0.56   10.3   0.2    2.1  2  DUF3974      Domain of unknown function (DUF3974)
        4.8    7.6   6.2        6.9    7.1   0.9    3.0  3  LRRC37       Leucine-rich repeat-containing protein 37 family


Domain annotation for each model (and alignments):
>> DDE_Tnp_1_7  Transposase IS4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  168.8   0.2   3.3e-53     2e-49       2     298 ..     499     844 ..     498     866 .. 0.90

  Alignments for each domain:
  == domain 1  score: 168.8 bits;  conditional E-value: 3.3e-53
  DDE_Tnp_1_7   2 pvelFelflpdkilerivkatNayakqk.........kkwleltaeElkaFlGllllmglvrlpsvedyWstkdfyg....npllseiMsreRFeeil 86 
                  p+++F+lf+++++++ +++ tN+ya  k         ++w+ +t  ElkaF+G+++ mg  + p+++dyW+++++ +    n++ls +++  RFe++ 
   EEA20317.1 499 PYQIFSLFFTEDLFKVLADNTNMYAYAKlsknmnphhRNWRSTTPGELKAFVGAQIYMGFTKEPQLKDYWDEEKHNKsvhaNHPLSNYITCFRFEQLK 596
                  9**********************************************************************9995555678***************** PP

  DDE_Tnp_1_7  87 salhladn........................stkkaekdklkkvrelidslnermqkvyrpsqtlvldeslvlfkgrvpfkqylpgkprkvgiklhv 160
                  + +h++++                        s+++ +    +kv  ++d l +  +++y ps+++++de +v  +gr +    +p+kp   g+k++v
   EEA20317.1 597 RFFHISEPsevpggfistyyrpepteeeelqlSEEQLSGIWWHKVHTVFDILRKASKNLYIPSSNISIDEAMVCSHGRSSHTYKMPNKPISQGFKIFV 694
                  ***********************9999888664444488999******************************************************** PP

  DDE_Tnp_1_7 161 lcdsqtgyilalelyegearnlrl..srelgktnalvlrLleplqgkg..rvvvmdnfftslellqeLakkgtyavGtlkknrsglPkeltqklpkge 254
                  l+d   gy + +++  ++++ ++    +el+kt ++v +L+++l + +  + +++dn+fts++l+++L++ ++ a+Gt +  ++++P+ l++ ++ g+
   EEA20317.1 695 LAD--HGYCYYFYPASRTKGVVEVgmAKELTKTGQMVYELVQTLPKDNktYDLYLDNYFTSVNLFKALREIQVGACGTTRP-HKEFPNLLKKLKDLGS 789
                  ***..9**********999877653378****************965555*******************************.77***88876666666 PP

  DDE_Tnp_1_7 255 llaryg......gplmllkwndrkkvkllstyss....qklveskersgqki.ka 298
                     +++      +++  ++w d++ v+ l+t+++    ++ +e+ +r+ qk+   
   EEA20317.1 790 YIPYHKvcaipvNDVLCVAWQDNNIVLALTTIHTvdqtDDYIERTRRRPQKTsTN 844
                  666666666666**********************877656699999999998434 PP

>> DUF3974  Domain of unknown function (DUF3974)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0      0.23   1.4e+03      55      85 ..     346     377 ..     334     392 .. 0.75
   2 ?   10.3   0.2   9.3e-05      0.56      66      97 ..     400     431 ..     357     438 .. 0.76

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.23
     DUF3974  55 tpflkeftkhplfy.rwirtegkkeqkvlnvl 85 
                   fl   t+ p+ +   +rt gkk q++ + l
  EEA20317.1 346 ERFLVHGTRSPFAWiTRLRTYGKKIQNTTTSL 377
                 5677777888864315679*******998876 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 9.3e-05
     DUF3974  66 lfyrwirtegkkeqkvlnvlfcaanertreqv 97 
                  f r+i+te +k q++l++lf   +e +re +
  EEA20317.1 400 SFRRFIQTEIEKAQHSLEMLFLLHEEESRESM 431
                 599**********************9999965 PP

>> LRRC37  Leucine-rich repeat-containing protein 37 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.9    0.0012       6.9      32      51 ..      64      83 ..      55      84 .. 0.87
   2 ?    1.7   0.1     0.056   3.3e+02      24      45 ..     317     337 ..     308     339 .. 0.86
   3 ?   -3.5   0.0       2.4   1.4e+04      24      41 ..     465     482 ..     459     488 .. 0.71

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0012
      LRRC37 32 vtvptPgqdqaqhptlpnvt 51
                + +p+ +++q q+p lp++t
  EEA20317.1 64 AVTPPSSHNQEQSPALPSIT 83
                788999*************9 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.056
      LRRC37  24 aqppthqevtvptPgqdqaqhp 45 
                 aq  + qe+  +  ++dq++hp
  EEA20317.1 317 AQMFVVQEAVMQ-ANEDQVEHP 337
                 677778999999.9*******9 PP

  == domain 3  score: -3.5 bits;  conditional E-value: 2.4
      LRRC37  24 aqppthqevtvptPgqdq 41 
                 +q p+ +ev+  + + d+
  EEA20317.1 465 KQIPEANEVRFEPIQTDK 482
                 789999999988655554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (877 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       437  (0.0243739); expected 358.6 (0.02)
Passed bias filter:                      375  (0.0209158); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.70u 0.29s 00:00:00.99 Elapsed: 00:00:00.47
# Mc/sec: 5661.69
//
Query:       EEA20318.1  [L=977]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (977 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1401  (0.0781416); expected 358.6 (0.02)
Passed bias filter:                      543  (0.0302861); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.79u 0.28s 00:00:01.07 Elapsed: 00:00:00.44
# Mc/sec: 6660.16
//
Query:       EEA20319.1  [L=1032]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1032 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       893  (0.0498076); expected 358.6 (0.02)
Passed bias filter:                      474  (0.0264376); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.74u 0.27s 00:00:01.01 Elapsed: 00:00:00.45
# Mc/sec: 6965.44
//
Query:       EEA20320.1  [L=1063]
Description: alpha-ketoglutarate dehydrogenase complex subunit Kgd1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.8e-64  216.1   0.0    4.9e-64  215.3   0.0    1.4  1  Transket_pyr     Transketolase, pyrimidine binding domain
    3.9e-59  200.1   0.0    5.7e-59  199.5   0.0    1.2  1  E1_dh            Dehydrogenase E1 component
    4.5e-57  192.0   0.0    7.5e-57  191.3   0.0    1.4  1  OxoGdeHyase_C    2-oxoglutarate dehydrogenase C-terminal
    3.2e-20   71.4   0.6    7.1e-20   70.3   0.6    1.6  1  2-oxogl_dehyd_N  2-oxoglutarate dehydrogenase N-terminus
  ------ inclusion threshold ------
      0.063   13.3   0.3       0.55   10.3   0.1    2.5  3  DUF2680          Protein of unknown function (DUF2680)


Domain annotation for each model (and alignments):
>> Transket_pyr  Transketolase, pyrimidine binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  215.3   0.0   1.4e-67   4.9e-64       2     178 .]     686     898 ..     685     898 .. 0.99

  Alignments for each domain:
  == domain 1  score: 215.3 bits;  conditional E-value: 1.4e-67
                   EEEHHHHHHHHHHHHHCTTTTEEEEESSTHHHHTTCHCCHHEGGT................TEGEEE--S-HHHHHHHHHHHHHHCT.TEEEEEEEE CS
  Transket_pyr   2 kiawrkaeaealaellkedpevvligaDvaggtfsvrkgllhdqg................egrvidsgisEqavlgfavGaalagp.llviveaqF 81 
                    i+w++aea+a+++l+ke+++v+++g+Dv++gtfs+r+++lhdq+                 + + +s++sE++vlgf++G++l++p  lv++eaqF
    EEA20320.1 686 NIDWATAEALAFGTLVKEGHHVRVSGQDVERGTFSQRHAVLHDQEseatytplqhitpdqgTFVISNSSLSEFGVLGFEYGYSLTSPnGLVMWEAQF 782
                   69*********************************************************999999******************************** PP

                   HHHHGGGHHGGHHHHHCHHHHHT--EEEEESBSGGGSTTGTTTSBSSHHHHHHTSTT...................EEEE--SSHHHHHHHHHHHHH CS
  Transket_pyr  82 gdFangAqiyadqairsgeakgklkvgvvtrlpigvgedGpehqsaeleaflrlipg...................lkvvrPsdpaetkhllrrair 159
                   gdFan+Aq+++dq+i sge k+ +++g+v+ lp+g++++Gpeh+s ++e++l+l+++                   +++v+ ++p++++h+lrr+++
    EEA20320.1 783 GDFANNAQCIIDQFIASGEVKWLQRSGLVVSLPHGYDGQGPEHSSGRMERWLQLCNEeprvfpspeklerqhqdcnMQIVCMTSPSNLFHILRRQLN 879
                   ************************************************************************************************* PP

                   SSS.SEEEEEE-SSEEC.T CS
  Transket_pyr 160 redrkPvvlrlpksllrhk 178
                   r++rkP++++++ksllrh+
    EEA20320.1 880 RQFRKPLIIFFSKSLLRHP 898
                   *****************85 PP

>> E1_dh  Dehydrogenase E1 component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  199.5   0.0   1.6e-62   5.7e-59       6     295 ..     297     613 ..     292     617 .. 0.90

  Alignments for each domain:
  == domain 1  score: 199.5 bits;  conditional E-value: 1.6e-62
                 HHHHHHHHHHHHHTTSS-S-----TT-HHHHHHHHHTS-TT..SEEEES.S--HHHHHHTT--..HHHHHHHHTT-T....TTSSGTT-..-E..BT.. CS
       E1_dh   6 lrrvedaldalykrkkrigfyhlsagqealkvgiaaaleke..Dliite.YReagvllargls..leeilaeltgkv....kgkggsrh.elmyaek.. 92 
                 +  +e++l+ ++ + kr+g++ ++ + + +k +i+ +++ +  D++i + +R++ ++l ++++   e+i++e+ g +    +g+g++++  +m  e+  
  EEA20320.1 297 SSSFESFLSTKFPNDKRFGLEGCETLVPGMKALIDRSVDYGvkDIVIGMpHRGRLNVLSNVVRkpNESIFSEFSGSAepsdEGSGDVKYhLGMNFERpt 395
                 567899999******************************9888****999************98899*********99***999999998777655412 PP

                 ....T..BEEE-SSTTTH..HHHHHHHHHHHH......HHTS---EEEEEEGGG.TT-HHHHHHHHHHHHTT--E...EEEEEEESEETTEEHHHH-S- CS
       E1_dh  93 ....esrilggngivgaq..vplvaGialaak......iegkkevailliGDgA.anqGdvyealnlaalwklpv...ifvveNNkygisTeaekasas 175
                      +++    ++++++   p+v G ++a +       + ++++ +ll+GD+A a+qG vye++ + al+ + +   +++v+NN++g++T+++ a+++
  EEA20320.1 396 psgkRVQLSLVANPSHLEaeDPVVLGKTRAIQhynndeKDFNTAMGVLLHGDAAfAAQGVVYETMGFHALPAYSTggtVHIVVNNQIGFTTDPRFARST 494
                 22113344444444444443777778888888987665555679******************************99*********************** PP

                 --GGG..TTTTS-EEEEETTSHHHHHHHHHHHHHHHHTTT--EEEEEEE--SS-SSTTSHSHSSSHHHHHHHHHHHH-HHHHHHHHHHHTTSS-HHHHH CS
       E1_dh 176 keladrargvgipglrVdgnDplavyeAvkfAaeraregkgpllielvtYRyggHsesDdpstyrtreeveevrkkkdpiqrlkelLvkkgvvseeelk 274
                 ++ +d a++  +p ++V+g+D++av ++++ Aa+++ e+k++++i++v+YR +gH+e D ps+++ + +++ + +kk ++ ++ ++L+++g  ++e  +
  EEA20320.1 495 PYCSDIAKAIDAPVFHVNGDDVEAVNYVCQIAADWRAEFKRDVVIDIVCYRKQGHNETDQPSFTQ-PLMYKRIAEKKSQLDIYVDKLISEGTFTKEDID 592
                 *****************************************************************.********************************* PP

                 HHHHHHHHHHHHHHHHHHHS- CS
       E1_dh 275 eiekevrkeveeavkkaeskk 295
                 e +k v  + ++ ++++++++
  EEA20320.1 593 EHKKWVWGMLNDSFDRSKDYQ 613
                 *****************9985 PP

>> OxoGdeHyase_C  2-oxoglutarate dehydrogenase C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  191.3   0.0   2.1e-60   7.5e-57       1     152 []     901    1053 ..     901    1053 .. 0.96

  Alignments for each domain:
  == domain 1  score: 191.3 bits;  conditional E-value: 2.1e-60
  OxoGdeHyase_C    1 rSsleelaegtsFqrvledeeeea.lkepekvkrvvlcsGkvyydLlkerekkekekdvaivriEqlyPfpfeelkeelekYpnakelvWvQeE 93  
                     rS++ e++ +++Fq++++d+++ a ++epek++rv++csG+vy +L+k+re+k+ ++++ai+r+Eql Pfp+++lke+l++Ypnak++vW+QeE
     EEA20320.1  901 RSDIGEFTGDSHFQWIIPDSAHGAsIDEPEKIERVIMCSGQVYAALIKHREAKG-IRNTAITRVEQLNPFPWAQLKENLDSYPNAKDIVWAQEE 993 
                     59999***************99768999***********************885.5************************************** PP

  OxoGdeHyase_C   94 pkNqGawsfveprletvlkek.kkkkkklryvgreasaspAtGskkvhkkeqealleeaf 152 
                     p N+Gawsfv+pr+et+l+ + ++++++++y+gr++sas+AtG k+ h ke+++lle+af
     EEA20320.1  994 PLNAGAWSFVQPRIETLLNATeHHNRRHVMYAGRAPSASVATGLKASHVKEEQDLLETAF 1053
                     *******************97689999*******************************98 PP

>> 2-oxogl_dehyd_N  2-oxoglutarate dehydrogenase N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.3   0.6     2e-23   7.1e-20       1      40 [.      88     127 ..      88     128 .. 0.97

  Alignments for each domain:
  == domain 1  score: 70.3 bits;  conditional E-value: 2e-23
  2-oxogl_dehyd_N   1 dsfLsgtnaaYiEelYeayleDPsSVdesWrayFknledg 40 
                      dsfL+g+ a+Yi+e+Y a+++DPsSV+ sW++yFkn+e+g
       EEA20320.1  88 DSFLQGNTANYIDEMYLAWRKDPSSVHISWQTYFKNMENG 127
                      7************************************997 PP

>> DUF2680  Protein of unknown function (DUF2680)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       1.1   4.1e+03      20      32 ..     326     338 ..     325     338 .. 0.88
   2 ?   10.3   0.1   0.00015      0.55      13      45 ..     563     598 ..     561     604 .. 0.90
   3 ?   -1.3   0.0      0.65   2.3e+03      33      44 ..     741     752 ..     740     754 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 1.1
     DUF2680  20 rKqivdKyVeaGl 32 
                 +K ++d  V++G+
  EEA20320.1 326 MKALIDRSVDYGV 338
                 5899*******96 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00015
     DUF2680  13 yqqiaelrKqi...vdKyVeaGllTkeqgekikkni 45 
                 y+ iae++ q+   vdK+++ G++Tke+ ++ kk++
  EEA20320.1 563 YKRIAEKKSQLdiyVDKLISEGTFTKEDIDEHKKWV 598
                 89999999998888****************999986 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.65
     DUF2680  33 lTkeqgekikkn 44 
                 +T++qg  +++n
  EEA20320.1 741 ITPDQGTFVISN 752
                 9******99998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1063 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       561  (0.0312901); expected 358.6 (0.02)
Passed bias filter:                      527  (0.0293937); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.78u 0.30s 00:00:01.08 Elapsed: 00:00:00.46
# Mc/sec: 7005.56
//
Query:       EEA20321.1  [L=680]
Description: PHD finger domain protein (Ing1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.6e-11   44.7   0.1    6.4e-11   42.7   0.1    2.0  1  ING           Inhibitor of growth proteins N-terminal histone
    5.7e-06   26.1   7.2    9.8e-06   25.4   7.2    1.4  1  PHD           PHD-finger
  ------ inclusion threshold ------
      0.023   15.0   2.5      0.054   13.8   2.5    1.6  1  zf-HC5HC2H    PHD-like zinc-binding domain
      0.061   13.7   0.0       0.15   12.4   0.0    1.7  1  DUF4378       Domain of unknown function (DUF4378)
       0.12   12.5   1.9       0.26   11.5   1.9    1.5  1  zf-HC5HC2H_2  PHD-zinc-finger like domain
        0.2   11.2   1.6       0.34   10.5   1.6    1.4  1  PHD_2         PHD-finger


Domain annotation for each model (and alignments):
>> ING  Inhibitor of growth proteins N-terminal histone-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.7   0.1   2.1e-14   6.4e-11       2      95 ..      74     197 ..      73     199 .. 0.90

  Alignments for each domain:
  == domain 1  score: 42.7 bits;  conditional E-value: 2.1e-14
                 HHHHHTSGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH............................TS..S-HHHHHHHHH..HHHHHHHHHH CS
         ING   2 LedyldsvenLPlelqrnltelreiDakvqellkeidskiekfl............................kngslqknekeeels..riqeelkeaq 70 
                 L +++d++ +LP e++r+ ++l+e+Dak   l +++++ + + +                             ++++++++k+++l   ri+++l++++
  EEA20321.1  74 LTHFTDAITALPREFRRHNSLLKEVDAKAWALEDNLHQLLLSASdsrpvpfpqnpapivdgevreyahalndPQNAESQESKQRRLLfdRIRHTLSDLM 172
                 889*************************99999999888888889999999*********************55566666666666667********** PP

                 HHHHHHHHHHHHHHHHHHHHHHHHH CS
         ING  71 elldeKiqlaqqaldlvdkhlrrLd 95 
                   +deK ++ + a + +d++l rL+
  EEA20321.1 173 LTADEKNHVLTNANEELDHQLYRLK 197
                 ***********************97 PP

>> PHD  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.4   7.2   3.3e-09   9.8e-06       1      51 [.     622     670 ..     622     671 .. 0.81

  Alignments for each domain:
  == domain 1  score: 25.4 bits;  conditional E-value: 3.3e-09
                 SBTTTTSTTSTTSCEEEETT..TS.CEEETTTSSSTHSHHSHHSSTBSSTTTHT CS
         PHD   1 rCavCkkksdeeeelvqCdg..Ck.rwfHqkClkppleseekpegewlCekCke 51 
                 +C  C++     +e+v Cd+  C  +wfH +C+++ + + ++   +w+C++Cke
  EEA20321.1 622 YC-YCNQ--VSFGEMVACDNdaCPtEWFHLSCVGLAKPPGRN--VKWYCTECKE 670
                 68.9999..789******7444*737**********995444..47******97 PP

>> zf-HC5HC2H  PHD-like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   2.5   1.8e-05     0.054       8      67 ..     595     652 ..     588     672 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.8e-05
  zf-HC5HC2H   8 ipevvfeeekeiemeeiedvekikkerkklkCylCkkkvGaciqCskkkC.kkafHvtCak 67 
                   ++v++ee+   +e+ ++ ++++ e++   Cy+ + + G ++ C++  C ++ fH+ C  
  EEA20321.1 595 KAKMVQQEEE---EESSREGDDEDDESEPRYCYCNQVSFGEMVACDNDACpTEWFHLSCVG 652
                 4455554444...4778888899999999999977788************4468*****75 PP

>> DUF4378  Domain of unknown function (DUF4378)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   5.1e-05      0.15      33     116 ..     132     205 ..     107     244 .. 0.67

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 5.1e-05
     DUF4378  33 idpslfeeleekkssssekkrreerserklLFDlvneiLaeilalelkrslaepsskvssakkrrkkklsgeqL.leevwseiee 116
                 +d ++ e  +       ++++++e  +r+lLFD +   L++ + ++        ++ v + +++   +l+++   l+ev+  i++
  EEA20321.1 132 VDGEVREYAHALNDP--QNAESQESKQRRLLFDRIRHTLSDLMLTAD------EKNHVLTNANE---ELDHQLYrLKEVHPFISN 205
                 555555554433332..344458899****************76442......22222222222...222222246666666664 PP

>> zf-HC5HC2H_2  PHD-zinc-finger like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   1.9   8.6e-05      0.26      35      88 ..     599     654 ..     573     671 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 8.6e-05
  zf-HC5HC2H_2  35 fsnvaerepvdvekikkerlkekCllCkkr.kGaciqCskkeCkt.afHvtCalaa 88 
                   +++++e e  +  + ++++++ + ++C++   G ++ C ++ C t  fH  C   a
    EEA20321.1 599 VQQEEEEESSREGDDEDDESEPRYCYCNQVsFGEMVACDNDACPTeWFHLSCVGLA 654
                   33333333344455556667888889998868***********76269****8665 PP

>> PHD_2  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   1.6   0.00012      0.34       4      36 .]     633     669 ..     630     669 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00012
       PHD_2   4 llsCd..kCsva.VHasCYGvskesdgee.WlCrrCe 36 
                 ++ Cd   C +  +H sC G+ k++  +  W+C  C+
  EEA20321.1 633 MVACDndACPTEwFHLSCVGLAKPPGRNVkWYCTECK 669
                 77887667888559*******999877556******5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (680 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2132  (0.118913); expected 358.6 (0.02)
Passed bias filter:                      666  (0.0371465); expected 358.6 (0.02)
Passed Vit filter:                        84  (0.00468515); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.96u 0.32s 00:00:01.28 Elapsed: 00:00:00.45
# Mc/sec: 4548.62
//
Query:       EEA20322.1  [L=639]
Description: Leucine Rich Repeat domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.9e-05   24.5   0.2    5.7e-05   22.9   0.2    1.9  1  F-box-like  F-box-like
  ------ inclusion threshold ------
      0.053   13.4   2.9       0.56   10.2   0.9    3.6  3  F-box       F-box domain
       0.14   12.2   5.7         16    5.8   0.0    4.9  4  LRR_6       Leucine Rich repeat
        0.7   10.4  13.1        2.9    8.4   0.3    4.8  6  LRR_4       Leucine Rich repeats (2 copies)


Domain annotation for each model (and alignments):
>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.2   1.3e-08   5.7e-05       1      47 [.     168     223 ..     168     224 .. 0.79

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 1.3e-08
  F-box-like   1 isrLPdEiLlqIFsy....Lpps.......dLlrlalVCrrWrrvaldtplLWrrlvl 47 
                 i +LP E+L+qI sy    Lpp+       dL+++ l++r  ++++l+   L+r++++
  EEA20322.1 168 IEDLPIEVLVQIISYlaveLPPNgytprnvDLIACLLTSRTLHSATLS--VLYRHITI 223
                 579**********996666443333333578***************76..6****986 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.9   0.00013      0.56       2      37 ..     167     213 ..     166     220 .. 0.89
   2 ?   -1.8   0.0      0.72   3.2e+03      29      38 ..     273     282 ..     272     286 .. 0.82
   3 ?   -1.7   0.0      0.64   2.9e+03       3      14 ..     356     367 ..     355     406 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00013
                 HHHHS-HHHHHHHHHTS-HHH...........HHHHCTT-HHHHHHH CS
       F-box   2 tlsrLPsevlrhILerLplsd...........llalrrVSkgwrili 37 
                 t+ +LP evl +I+++L               l+a+ ++S+++++++
  EEA20322.1 167 TIEDLPIEVLVQIISYLAVELppngytprnvdLIACLLTSRTLHSAT 213
                 799**************999999999999999999999999999876 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.72
                 T-HHHHHHHT CS
       F-box  29 VSkgwrilid 38 
                 +Sk++ +++d
  EEA20322.1 273 TSKTLLQCLD 282
                 8999999998 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 0.64
                 HHHS-HHHHHHH CS
       F-box   3 lsrLPsevlrhI 14 
                 +s LPs+v ++ 
  EEA20322.1 356 CSGLPSAVFEKL 367
                 788999966554 PP

>> LRR_6  Leucine Rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.1      0.21   9.2e+02       4      16 ..     373     385 ..     372     392 .. 0.81
   2 ?    1.0   0.1      0.13   5.7e+02       5      13 ..     398     406 ..     394     411 .. 0.82
   3 ?    5.8   0.0    0.0036        16       3      18 ..     457     472 ..     455     472 .. 0.90
   4 ?    2.9   0.0     0.032   1.5e+02       4      17 ..     483     496 ..     481     501 .. 0.88

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.21
       LRR_6   4 hLteLdLsgNdIg 16 
                 ++t+LdL   +++
  EEA20322.1 373 NVTHLDLGRTQVT 385
                 689****998876 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.13
       LRR_6   5 LteLdLsgN 13 
                 +t+L+Ls +
  EEA20322.1 398 ITHLNLSKC 406
                 79*****98 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.0036
       LRR_6   3 thLteLdLsgNdIgDe 18 
                 ++L++L+L+g  I+ e
  EEA20322.1 457 STLRSLNLNGARITTE 472
                 89*********99976 PP

  == domain 4  score: 2.9 bits;  conditional E-value: 0.032
       LRR_6   4 hLteLdLsgNdIgD 17 
                 hL+eL Lsg d++ 
  EEA20322.1 483 HLEELGLSGADLSP 496
                 9********99876 PP

>> LRR_4  Leucine Rich repeats (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.4       3.1   1.4e+04      12      30 ..     277     283 ..     266     287 .. 0.48
   2 ?   -2.5   0.0       1.8   7.9e+03      19      32 ..     309     321 ..     298     329 .. 0.65
   3 ?   -2.8   0.0       2.3     1e+04      19      33 ..     343     356 ..     339     360 .. 0.75
   4 ?    8.4   0.3   0.00065       2.9       2      33 ..     373     406 ..     372     435 .. 0.85
   5 ?    6.9   0.3     0.002         9       3      41 ..     459     496 ..     457     501 .. 0.76
   6 ?    0.4   0.0      0.21   9.5e+02      23      39 ..     517     530 ..     514     540 .. 0.53

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 3.1
                 ---E-S-HHH-TT--EEE- CS
       LRR_4  12 qltdiplleklpnLkeLdL 30 
                              L+ LdL
  EEA20322.1 277 L------------LQCLDL 283
                 3............444443 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 1.8
                 HHH-TT--EEE-.- CS
       LRR_4  19 leklpnLkeLdLsg 32 
                 + +lp+L+ +d  g
  EEA20322.1 309 F-GLPKLRAVDFCG 321
                 4.499999888534 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 2.3
                 HHH-TT--EEE-.-S CS
       LRR_4  19 leklpnLkeLdLsgN 33 
                 l  lp Lk ++L+++
  EEA20322.1 343 LV-LPLLKRVSLHEC 356
                 45.899999999655 PP

  == domain 4  score: 8.4 bits;  conditional E-value: 0.00065
                 S--EEE--SS---E-S-HHH-TT...--EEE-.-S CS
       LRR_4   2 nLevLdLsnNqltdiplleklpn...LkeLdLsgN 33 
                 n ++LdL+ +q+t+  ll+ lp     ++L+Ls +
  EEA20322.1 373 NVTHLDLGRTQVTETALLS-LPTsaqITHLNLSKC 406
                 89***********988866.444444******887 PP

  == domain 5  score: 6.9 bits;  conditional E-value: 0.002
                 --EEE--SS---.E-S-.HHH-TT.--EEE-.-S-----GGG CS
       LRR_4   3 LevLdLsnNqlt.dipl.leklpn.LkeLdLsgNnlitdlde 41 
                 L++L+L++ ++t +  + l  l++ L+eL Lsg     dl++
  EEA20322.1 459 LRSLNLNGARITtEHVPlLVPLTKhLEELGLSGA----DLSP 496
                 9***********5555564455555******997....7764 PP

  == domain 6  score: 0.4 bits;  conditional E-value: 0.21
                 TT--EEE-.-S-----G CS
       LRR_4  23 pnLkeLdLsgNnlitdl 39 
                 p L++Ld+s     t++
  EEA20322.1 517 PALHYLDVSKV---TSI 530
                 45666666443...222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (639 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       503  (0.0280551); expected 358.6 (0.02)
Passed bias filter:                      451  (0.0251548); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.44
# Mc/sec: 4347.83
//
Query:       EEA20323.1  [L=641]
Description: RNA polymerase II transcription factor protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.4e-30  103.5  11.3      3e-15   56.0   0.8    3.2  3  BSD         BSD domain
    1.8e-27   95.5   0.7    4.9e-27   94.1   0.1    2.1  2  PH_TFIIH    TFIIH p62 subunit, N-terminal domain
  ------ inclusion threshold ------
        0.3   11.6   6.1        8.5    6.8   1.1    3.1  3  DUF3245     Protein of unknown function (DUF3245)


Domain annotation for each model (and alignments):
>> BSD  BSD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.1   0.3   1.9e-18   1.2e-14       2      58 .]     146     207 ..     143     207 .. 0.93
   2 !   56.0   0.8     5e-19     3e-15       5      58 .]     227     279 ..     222     279 .. 0.91
   3 ?   -2.6   0.3      0.96   5.8e+03      39      45 ..     526     532 ..     524     534 .. 0.80

  Alignments for each domain:
  == domain 1  score: 54.1 bits;  conditional E-value: 1.9e-18
         BSD   2 dnkfkldkteeiaqsllkedpeLrklynel.......VPskvseeqFWsrYfyllrahaieeeq 58 
                 d+k+k  +++e++qsllk+d +L+++++e         ++ ++ +qFWs +++llrahaie +q
  EEA20323.1 146 DDKLK--TDAELQQSLLKSDANLQRMFMESlrtrpetLSVGQFASQFWSSRVHLLRAHAIERAQ 207
                 55666..******************************************************876 PP

  == domain 2  score: 56.0 bits;  conditional E-value: 5e-19
         BSD   5 fkldkteeiaqsllkedpeLrklynelVPskvseeqFWsrYfyllrahaieeeq 58 
                  kl++t+e++q+++ ++p ++k+y+e+VP+ +se+qFWsr+f++++++++++e+
  EEA20323.1 227 TKLNITKEQIQLIFHQHPLVKKVYDENVPK-LSEQQFWSRFFQSRLFKKLRGER 279
                 3588**************************.*******************9985 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 0.96
         BSD  39 eqFWsrY 45 
                 +qFW  +
  EEA20323.1 526 NQFWNAF 532
                 79**987 PP

>> PH_TFIIH  TFIIH p62 subunit, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.1   0.1   8.2e-31   4.9e-27       1      87 []       9      96 ..       9      96 .. 0.95
   2 ?   -2.8   0.0       1.4   8.3e+03      41      56 ..     226     241 ..     222     253 .. 0.64

  Alignments for each domain:
  == domain 1  score: 94.1 bits;  conditional E-value: 8.2e-31
    PH_TFIIH  1 sykKkdGtLtlte..krleWtpdasssapsvsiplseIknlqispagsaKvmLklvlkedkseeesytFtFtngsearkerdavkdlLq 87
                sykKkdGtLt+++  k+++W+p+a+++ ++v++p+++ +nlq++pa+++KvmL+++++++ +++e+y+FtFt+g++ar+e+da+kd+L+
  EEA20323.1  9 SYKKKDGTLTVSKdqKSISWIPAAGGAGSAVTVPVQNMTNLQQTPASNPKVMLRIFAQQN-ETQEQYVFTFTSGTNARAEADAIKDVLS 96
                6************99*******8888889*****************************44.4899*********************996 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1.4
    PH_TFIIH  41 ispagsaKvmLklvlk 56 
                 +++ +  K +++l+ +
  EEA20323.1 226 VTKLNITKEQIQLIFH 241
                 4555555666777766 PP

>> DUF3245  Protein of unknown function (DUF3245)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0    0.0029        17      25      53 ..     156     184 ..     144     195 .. 0.85
   2 ?    6.8   1.1    0.0014       8.5     124     147 ..     455     479 ..     447     481 .. 0.68
   3 ?   -3.2   0.2       1.7     1e+04      26      41 ..     565     581 ..     550     590 .. 0.41

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0029
     DUF3245  25 qsdekktdeelqkeedeiftavpetlGlG 53 
                 q+   k+d++lq+   e +  +petl +G
  EEA20323.1 156 QQSLLKSDANLQRMFMESLRTRPETLSVG 184
                 4455599********************99 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.0014
     DUF3245 124 ddddddded.esRskavgkkssskK 147
                 d+ddddded e  sk+vg k +++K
  EEA20323.1 455 DEDDDDDEDeEKASKVVGSKINMQK 479
                 6666666664777788887665554 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 1.7
     DUF3245  26 sdekktd.eelqkeede 41 
                 + ek+t+ ++l++   e
  EEA20323.1 565 ETEKETEiNKLKQHARE 581
                 11122221223333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (641 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1213  (0.0676558); expected 358.6 (0.02)
Passed bias filter:                      610  (0.0340231); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.69u 0.29s 00:00:00.98 Elapsed: 00:00:00.46
# Mc/sec: 4210.24
//
Query:       EEA20324.1  [L=521]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.7e-41  142.4  25.8    2.5e-41  141.8  25.8    1.3  1  MFS_1       Major Facilitator Superfamily
    8.7e-11   41.3  12.1    8.7e-11   41.3  12.1    3.0  3  Sugar_tr    Sugar (and other) transporter
  ------ inclusion threshold ------
      0.017   14.0   4.3      0.088   11.7   3.4    2.4  2  MFS_1_like  MFS_1 like family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  141.8  25.8   4.2e-45   2.5e-41       2     352 ..      42     460 ..      41     461 .. 0.82

  Alignments for each domain:
  == domain 1  score: 141.8 bits;  conditional E-value: 4.2e-45
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgag 100
                 +la+++s l+++i++p++  ++++dlg+++s + l +t+y++++++a  ++G +sd +Grr +++++l+++ ++ l+l+f+ss+++l+vlr +q++g++
  EEA20324.1  42 SLAGAFSPLSSNIYFPSIA-TISDDLGVDASLVALTITVYMVVQGIAPSLFGTFSDTCGRRLTFVISLTIYTAANLALAFTSSYPMLMVLRGVQAAGSA 139
                 68999**************.******************************************************77777877777************** PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee........... 188
                 a ++++a +iad++ ++erg  +g  ++   +G ++gp++gg+l s++g+r++f++l ++s+l++   +++lpe++++ + + ++++            
  EEA20324.1 140 ATISISAGVIADIACPDERGGFMGTNAGVRMMGQAIGPIIGGALNSAWGFRSIFWLLFVMSALVLSALIVFLPETQRSVAGNGSIPLTgfqkpliytlk 238
                 ****************************************************************77777999777777777777777777777777777 PP

       MFS_1 189 ................kgtgpaplvpawkallkdpvlw......illialllfffgfsglltllplylqevlglsglllaglllallalvgailallag 265
                                  + +p+  ++ +k+ +++   +      +ll+  +++ +++s++++ ++++l   + + + +++gl +   ++++++++l +g
  EEA20324.1 239 pprawkeaqytdqkatTQAQPRTKIS-FKKAFAPMIYLfekdiaALLAWGAVAYTAWSMVTSSTTTLLLHSFPFLTQWQLGLCFLPNGFGCVCGSLSTG 336
                 77777777777555554445555555.66666666443566666566666666669999999999987888888866********************** PP

       MFS_1 266 rlsdr.............................lgrrrrlllallllllaalglallavt.....ssavllllvlvl....iGfglgfvfpsllalas 326
                 +l+dr                             +++r rl+  ++l+l++al l+  ++      + ++  l++ ++    i  ++  +f +  +++ 
  EEA20324.1 337 WLLDRsfrhaqirfkeqhgipaeesvvsrsdfpyVKARLRLVPLFSLGLMVALVLYGPSFEfndlrKYYTPNLAAPLIlqfvIAYTATAIFNINSTVLI 435
                 *****************9999999999999977666666666666666666666666666698888444444444444132244444444888888888 PP

       MFS_1 327 dlappeeagtasglfntagslggalg 352
                 d +p + ag a++l+n++++l ga g
  EEA20324.1 436 DCFPDRPAG-ATALNNLCRCLLGAAG 460
                 888867777.**********999877 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.3  12.1   1.5e-14   8.7e-11      20     201 ..      45     221 ..      28     229 .. 0.88
   2 !    4.4   0.0    0.0024        14      43      73 ..     292     342 ..     234     350 .. 0.70
   3 ?   -0.4   1.4     0.065   3.9e+02     290     361 ..     414     487 ..     381     493 .. 0.79

  Alignments for each domain:
  == domain 1  score: 41.3 bits;  conditional E-value: 1.5e-14
                 GGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHH CS
    Sugar_tr  20 gafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGl 118
                 gaf+ l++ +++    + +++    ++l+ l+  +++v++ i   ++g+++d+ GR+ +++i+ +++ ++++  a++    s+ +l+v R +   g  +
  EEA20324.1  45 GAFSPLSSNIYFPSIATISDDLGVDASLVALTITVYMVVQGIAPSLFGTFSDTCGRRLTFVISLTIYTAANLALAFTS---SYPMLMVLRGVQAAGSAA 140
                 6666666666666666666666667889999***********************************************...9***************** PP

                 HHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHH.HHHHHHGGGS---HHHHHHT CS
    Sugar_tr 119 asvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpa.llllilllflPESPrylvek 201
                 +  ++   i+ iA ++ Rg +++ +     +G+ ++ i+g +ln     +g+r  ++l +v++ l+l++l++flPE+ r    +
  EEA20324.1 141 TISISAGVIADIACPDERGGFMGTNAGVRMMGQAIGPIIGGALNSA---WGFRSIFWLLFVMSaLVLSALIVFLPETQRSVAGN 221
                 ******************999999999************9998764...77******99987615566777******9987665 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.0024
                 H.......................HHHHHHHTHHHHHHHHHHHHHHHHHHT CS
    Sugar_tr  43 e....................ssvlsglivsiflvGaiiGslfagllgdrf 73 
                 +                    ++ ++gl++    +G+++Gsl +g+l dr 
  EEA20324.1 292 TawsmvtsstttlllhsfpflTQWQLGLCFLPNGFGCVCGSLSTGWLLDRS 342
                 0444444444445555566657889999999999**************996 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 0.065
                 HHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH....HHHHTTSS...CHHHHHHHHHHHH CS
    Sugar_tr 290 llvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilg..ivalllvakskaasivaivfialfia 361
                 +l+ +i ++ ++++ + +  l+d f  R+   + +   + c++  +   v  +l ++ ka++  +iv  a+f++
  EEA20324.1 414 ILQFVIAYTATAIFNINSTVLIDCFPDRPAGATALNNLCRCLLGAAgvSVIQPLIDALKAMKSFSIVSAAVFLC 487
                 45556778888888999999999999999999988777777777775556667777779999999999999987 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   3.4   1.5e-05     0.088     220     378 ..      27     188 ..      10     195 .. 0.80
   2 ?    4.1   0.0    0.0028        17      42     107 ..     168     276 ..     162     436 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 1.5e-05
  MFS_1_like 220 nilknpeviifllvalilgmswgiienF....lflYLkelgasntllGslvalgvvaeiplfffaeklleklGhvklliiallayilrfllyaiienaw 314
                 +il++++ + +++++ + g+++ +  n     +    ++lg   +l+  ++++ +v + +   +     +++G +   +i+l++y++  l +a++++  
  EEA20324.1  27 HILSKRQKWNLVIFVSLAGAFSPLSSNIyfpsIATISDDLGVDASLVALTITVYMVVQGIAPSLFGTFSDTCGRRLTFVISLTIYTAANLALAFTSSYP 125
                 67778888888888888888877777752222333448999999999999999988888888888899999***99*******************8888 PP

  MFS_1_like 315 lvlpievLhgisfgllwaaaveyvskiapksleatgqgllsglyfglGralGsliGGllwdlks 378
                 +++++   +++  +++ ++ + ++++ia +  ++  +g  +g+   +G+a+G +iGG+l    +
  EEA20324.1 126 MLMVLRGVQAAGSAATISISAGVIADIACPDERGGFMGTNAGVR-MMGQAIGPIIGGALNSAWG 188
                 88888888888888888999999999999999999999999995.59**********9865555 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.0028
  MFS_1_like  42 ilpltsilsppiwgvlaDrfgkrkkvvilslllsavlflsllfip......................................pskerqeesklevsva 102
                 ++++ + ++p i g+l    g r    +l ++ ++vl + ++f+p                                      ++  +q ++++++s++
  EEA20324.1 168 VRMMGQAIGPIIGGALNSAWGFRSIFWLLFVMSALVLSALIVFLPetqrsvagngsipltgfqkpliytlkpprawkeaqytdQKATTQAQPRTKISFK 266
                 677888899999999999999999999999999999999999999777777777777777777777777776666665555544444444455555544 PP

  MFS_1_like 103 qdvd.....a 107
                 + +      +
  EEA20324.1 267 KAFApmiylF 276
                 4444555553 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (521 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       718  (0.0400469); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.72u 0.38s 00:00:01.10 Elapsed: 00:00:00.58
# Mc/sec: 2684.43
//
Query:       EEA20325.1  [L=314]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0011   19.5   0.5     0.0011   19.5   0.5    1.7  2  DUF1751   Eukaryotic integral membrane protein (DUF1751)


Domain annotation for each model (and alignments):
>> DUF1751  Eukaryotic integral membrane protein (DUF1751)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.1      0.43   7.8e+03      77      77 ..      31      31 ..       8      52 .. 0.53
   2 !   19.5   0.5     6e-08    0.0011      28      97 ..      75     143 ..      58     145 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.43
     DUF1751 77 e 77
                 
  EEA20325.1 31 A 31
                1 PP

  == domain 2  score: 19.5 bits;  conditional E-value: 6e-08
     DUF1751  28 lltlllggkylErlWgskEllkFilvvnvitnllvvlltlllylvtkseelllvpisGlagilagflval 97 
                 ++ l++  +++Er+Wgs+ l+ Fil v   t +++ ll  l+    +  + l +  sG +++++++lv +
  EEA20325.1  75 AAMLAYHMRVVERIWGSRKLATFILTVLPYTTIITPLLLALVLHPLSLGT-LNYLPSGPTAVMFALLVQY 143
                 56789999*******************99999999887777666555555.6666788888888888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (314 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       713  (0.039768); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.34s 00:00:00.99 Elapsed: 00:00:00.57
# Mc/sec: 1645.99
//
Query:       EEA20326.1  [L=201]
Description: hypothetical protein PMAA_041720 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.8e-15   55.4   0.0    4.7e-15   55.1   0.0    1.0  1  Glyco_hydro_127  Beta-L-arabinofuranosidase, GH127


Domain annotation for each model (and alignments):
>> Glyco_hydro_127  Beta-L-arabinofuranosidase, GH127
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.1   0.0   2.6e-19   4.7e-15     416     519 .]      12     107 ..       6     107 .. 0.86

  Alignments for each domain:
  == domain 1  score: 55.1 bits;  conditional E-value: 2.6e-19
                      EEEEEE-TTSSSEEEEEEEETT--CEEEEEEE-TT-S-.EEEEETTEEE--S-STTEEEEEEEE--TT-EEEEEE---EEEEE--TT-CCGTTE CS
  Glyco_hydro_127 416 eleqetnyPwegkvkltvktqkkaeftlklRiPgWaaa.atltvnGkkvvvkkksdgYleiereWkkgdkvelelpmsvrleeanpkvrddank 508
                       ++q+tn+Pw+g+v+l++  + +++++l+lRiP+Waa+ +t +    +++  + +dgYl +    +   +++l++p+++r ++a+pk+   +++
       EEA20326.1  12 VISQRTNLPWSGDVELKI--SGPKAVKLALRIPDWAASnYTCR---SSLSGGELHDGYLHLPAVAN--ATINLTFPLQPRKVYAHPKTG--KDE 96 
                      689***************..8999***********66536655...34466779*******98876..68**************99775..678 PP

                      EEEEETTEEEE CS
  Glyco_hydro_127 509 vavlrGPlvla 519
                       +++rGPlv++
       EEA20326.1  97 ICIMRGPLVYC 107
                      9*********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (201 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       230  (0.0128284); expected 358.6 (0.02)
Passed bias filter:                      221  (0.0123264); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.45
# Mc/sec: 1354.42
//
Query:       EEA20327.1  [L=238]
Description: DUF1680 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.3e-32  112.2   0.0    2.6e-32  112.0   0.0    1.0  1  Glyco_hydro_127  Beta-L-arabinofuranosidase, GH127


Domain annotation for each model (and alignments):
>> Glyco_hydro_127  Beta-L-arabinofuranosidase, GH127
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.0   0.0   1.4e-36   2.6e-32      52     221 ..      43     211 ..      10     228 .. 0.89

  Alignments for each domain:
  == domain 1  score: 112.0 bits;  conditional E-value: 1.4e-36
                      --TTT-TTHHHHHHHHHHHHHHHHH..--HHHHHHHHHHHHHHHHHCHSSS-B-GCCTHHSSEETTEESH..----HHHHHHHHHHHHHHHHHH CS
  Glyco_hydro_127  52 ktgeelrdgdlgkwleavalllast..kdkelekrldrlvdelakaQqedGYlsavtelkneakkeawap..dshelYnlgkliegavayyqat 141
                       ++++l+   ++++ ea+++ l ++  +d +l+++++++vd++ +aQ+edGYl+++++ +  +++++w++  d+helY+ g+l+e+ vay  +t
       EEA20327.1  43 PFQQSLTPKNHYNVTEAACYFLLKNddDDANLRQEVEQAVDMIRAAQHEDGYLNSYYTVR--GISKRWTNvrDMHELYCPGHLVEACVAYEILT 134
                      56778888999*********99776115678*****************************..*********77********************* PP

                      --HHHHHHHHHHHHHHHHHHCCS-CCHHHHHTTTHHCTHHHHHHHHHHHHT-CHHHHHHHHCCHHCCHCCT-HCTTT-SS CS
  Glyco_hydro_127 142 gkeklldvatrladyleevleklgdeqlqkalvpehggieealvklyelTgdkrYldlAkrfidergldpeklaykqdel 221
                      ++ +ll+ ++++ +++   ++++g+e+++ +++p+h +ie +l++ly+lT d+  l+lAk+fi er ++ e+ +   d+ 
       EEA20327.1 135 DSGRLLEPVMKALRHV---DSVFGPEEGKLHGYPGHPEIELGLLRLYNLTKDPLPLKLAKYFILERCQKDENGEIFYDHE 211
                      ****************...***********************************************99886666655554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (238 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       489  (0.0272742); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1538.45
//
Query:       EEA20328.1  [L=185]
Description: alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    0.00023   22.2   0.0     0.0004   21.4   0.0    1.6  1  ADH_zinc_N_2  Zinc-binding dehydrogenase
     0.0056   16.6   0.0     0.0089   15.9   0.0    1.4  1  ADH_N         Alcohol dehydrogenase GroES-like domain


Domain annotation for each model (and alignments):
>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0   4.5e-08    0.0004      90     133 .]     142     182 ..      60     182 .. 0.68

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 4.5e-08
                   HHHHHHHHHHHH----EEEEEEGGGHHHHHHHHHSS--SSEEEE CS
  ADH_zinc_N_2  90 leelaalieeGklrpvvdrvfpleeaaeAhrylesgrarGKiVl 133
                   ++++ + +e    +pv+dr+ ++e+a+eA+ yl  g++ G +++
    EEA20328.1 142 IKTVYEPFEP---HPVIDRTIDFEQAREALNYLYGGSHLGEVII 182
                   4444444444...5**************************9986 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   9.9e-07    0.0089       2      48 ..      29      78 ..      28     100 .. 0.90

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 9.9e-07
                TEEEEEEEEEEE-HHHHHHHTTS...TTTTSSSSEE---EEEEEEEEEST CS
       ADH_N  2 gevlikvkaagiCgsDlhilkgg...kelevklplilGHEivGeveevgp 48
                +evl+++  +++++ D +i++g+   + +  ++pli+  +++G++++v  
  EEA20328.1 29 DEVLVNIDRVALNRRDAKIINGDfkdSYPDPSHPLIPASDASGTIVQVTT 78
                89********************99888889999*************9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (185 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       350  (0.0195214); expected 358.6 (0.02)
Passed bias filter:                      303  (0.0169); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.21s 00:00:00.63 Elapsed: 00:00:00.39
# Mc/sec: 1427.50
//
Query:       EEA20329.1  [L=319]
Description: glycerol dehydrogenase (GldB), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.3e-50  170.0   0.0    1.8e-49  168.6   0.0    1.6  1  Aldo_ket_red  Aldo/keto reductase family


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  168.6   0.0   9.8e-54   1.8e-49       2     292 ..      18     295 ..      17     297 .. 0.94

  Alignments for each domain:
  == domain 1  score: 168.6 bits;  conditional E-value: 9.8e-54
                   EEEE-SSS-ST.TS-HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH.....-TTTGGG-EEEEEE--SSSTTSSSS-HHHHHHHHHHH CS
  Aldo_ket_red   2 lglGtwqlgskeeiskeealellrraleaGinffDtAevYgkgqseellGealkk.....srkkreeviiatKvdlrdaeiksglskenireslees 93 
                   +g+Gt + ++    +k e ++++  al  G++++D+A++Y    +e+++G a+++      ++kre+++i+tKv      ++  ++ e+++ sle+s
    EEA20329.1  18 VGFGTFANEG----AKGETYKAVTCALRVGYRHLDCAWYY---LNEDEVGDAVQDflkenPSVKREDIFITTKV------WNHLHRYEDVIWSLENS 101
                   6888887776....7999**********************...********99999999999************......***************** PP

                   HHHHT-S-EEEEEE-S--TTS-.......................HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHHHHTTT--EEEEE-B-BTT- CS
  Aldo_ket_red  94 lkrLgtdyvDllllHrpdpslp......................sieevldaleelvkeGkiraiGvSnfsveqlekakkkkkvkivavqveynllr 168
                   lkrL+t+yvDl+l+H+p  + +                      + e +++a+ee ++  k+raiGvSn++++ +e++k+ +k+++ ++qve +++ 
    EEA20329.1 102 LKRLKTSYVDLFLVHWPVAAEKdgqekpkigpdgkyvilhdlteNPEPTWRAMEEIYEDKKARAIGVSNWTIKGIEQLKSFAKIPPHVNQVEIHPF- 197
                   ********************99**************************************************************************. PP

                   HHHHTTHHHHHHHTT-EEEEBSTTGGGTTGTTTSS---SSSCCC-------TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTSTT-SEEEE--S CS
  Aldo_ket_red 169 eleeegllelckkkgvpliaysplggGlltgkyqseedkedkeprkdlkrdertsknldaaeelselakehgvslaqlalryalsqpavgivipgas 265
                    l +++l+ ++ k+++   aysplg+          ++++               ++   + +l+++a+ +g +laq+ +++ +   ++ +v+p++s
    EEA20329.1 198 -LPNNELVNYLFKNNILPQAYSPLGSQNQV------PSTG---------------EKVSENLTLKNIAERRGFTLAQVLIAWGI--RRGYVVLPKSS 270
                   .************************43322......2222...............3357899**********************..9********** PP

                   SHHHHHHHHGGGG----HHHHHHHHHH CS
  Aldo_ket_red 266 nieqlednldalelklseeevaeldel 292
                   +++++e n++++  +l++e++ae++++
    EEA20329.1 271 TPSRIESNFKSV--QLTDEDFAEVNAV 295
                   ************..*********9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (319 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       561  (0.0312901); expected 358.6 (0.02)
Passed bias filter:                      527  (0.0293937); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2234.87
//
Query:       EEA20330.1  [L=498]
Description: phosphatidyl synthase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-20   73.6   0.0    2.1e-20   72.7   0.0    1.5  1  Hydrolase_6     Haloacid dehalogenase-like hydrolase
    8.9e-20   70.5   0.0    2.1e-19   69.4   0.0    1.7  1  Hydrolase_like  HAD-hyrolase-like
     0.0015   18.7   0.0      0.062   13.4   0.0    2.2  2  HAD_2           Haloacid dehalogenase-like hydrolase
     0.0097   16.2   0.0        4.6    7.5   0.0    2.4  2  Hydrolase       haloacid dehalogenase-like hydrolase
  ------ inclusion threshold ------
      0.026   13.4   0.1      0.042   12.8   0.1    1.2  1  5-nucleotidase  5'-nucleotidase


Domain annotation for each model (and alignments):
>> Hydrolase_6  Haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.7   0.0   5.9e-24   2.1e-20       1     100 [.     145     249 ..     145     250 .. 0.95

  Alignments for each domain:
  == domain 1  score: 72.7 bits;  conditional E-value: 5.9e-24
                  EEEESTTTSEETTEE-TTHHHHHHHHHHTT.....-EEEEEE---SS-HHHHHHHH.HHTT----GGGEEEHHHHHHHHHHHHSXXXEEEEESXH..H CS
  Hydrolase_6   1 flfDidGvLwrgdkaipgaaealnalraag.....kpvvllTNnsskseeeyakkl.eklgvditeeqvvtsataaaeylkkrkadkkvlvigee..g 90 
                  f+fDidGvL +g++ai +a e+l++l+  +     +p +llTN+++k+eee++++l e l+ +i+ +q+++s+t+++++ +     ++vlv+g+e  +
   EEA20330.1 145 FAFDIDGVLAHGNQAILEAREVLKMLNGDNelgikIPHILLTNGGGKTEEERCQQLsEILESPISVDQFIQSHTPMQALSEY---YETVLVVGGEgyK 239
                  78***************************99*************************5559*****************99987...99********566 PP

                  HHHHHHHTTX CS
  Hydrolase_6  91 lreelkeagf 100
                  +r++++++gf
   EEA20330.1 240 CRDVAQSYGF 249
                  *********9 PP

>> Hydrolase_like  HAD-hyrolase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.4   0.0   5.8e-23   2.1e-19       1      75 []     377     463 ..     377     463 .. 0.87

  Alignments for each domain:
  == domain 1  score: 69.4 bits;  conditional E-value: 5.8e-23
                     E.STTSSHHHHHHHHHH..........---GGGEEEEES-TTTHHHHHHHCT-EEEEESSSSS-TTTHHHHHHHHT-..--SEEES- CS
  Hydrolase_like   1 vlgKPepemydfalevl..........gsdpeevlmiGDrlatDiagAnnaGwksvLVltGvtrpedleepehkpty..vaddlaea 75 
                     v+gKPe  +y++a evl          +  p++v+miGD++a+Di+g+n +Gw+++LV+tGv++ +  e ++ +p+   v+d++ +a
      EEA20330.1 377 VYGKPELATYKYADEVLkawmeeihneNRLPQNVYMIGDNPASDIIGGNMYGWNTCLVRTGVFQGGPGENDPNSPANfgVFDNVLDA 463
                     69***************8888877655444999********************************9999877655543789999886 PP

>> HAD_2  Haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.0     0.023        83       3      20 ..     147     164 ..     145     228 .. 0.85
   2 !   13.4   0.0   1.7e-05     0.062     123     177 ..     375     433 ..     358     434 .. 0.82

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.023
       HAD_2   3 FDlDgTlldteeliiqaf 20 
                 FD+Dg+l+  +++i++a 
  EEA20330.1 147 FDIDGVLAHGNQAILEAR 164
                 **************9974 PP

  == domain 2  score: 13.4 bits;  conditional E-value: 1.7e-05
       HAD_2 123 dvivtsedvekkKPdpeviekalekl...klkkeeviyvGDsp.tDieaakkagikvia 177
                  v++++ +    K + ev+++++e+    +  +++v ++GD+p +Di+++   g +++ 
  EEA20330.1 375 RVVYGKPELATYKYADEVLKAWMEEIhneNRLPQNVYMIGDNPaSDIIGGNMYGWNTCL 433
                 567777777778888899999999986667789******************99999876 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.5   0.0    0.0013       4.6       3      22 ..     144     163 ..     143     268 .. 0.82
   2 !    6.4   0.0    0.0026       9.5     171     207 ..     385     425 ..     349     428 .. 0.62

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0013
                 EEEEESBTTTBCHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxx RF
   Hydrolase   3 tvvfDkdGTLttgepsvedv 22 
                 +++fD+dG+L +g++ + ++
  EEA20330.1 144 AFAFDIDGVLAHGNQAILEA 163
                 799***********555443 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.0026
                 STTTSHHHHHHHHHHHTST...GGGEEEEESSHH.HHHHHH CS
                 xxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxx.xxxxxx RF
   Hydrolase 171 vakpspegkvaaireLqgk...peevamVGDgvn.Daaala 207
                   k   e ++a ++e+  +   p++v m+GD++  D+ ++ 
  EEA20330.1 385 TYKYADEVLKAWMEEIHNEnrlPQNVYMIGDNPAsDIIGGN 425
                 4455667777788888533356***********99997765 PP

>> 5-nucleotidase  5'-nucleotidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.1   1.2e-05     0.042      95     138 ..     115     158 ..     109     182 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.2e-05
  5-nucleotidase  95 dvreaieagvaaalvleskkekeeeeeelriaFDgDavlfsdes 138
                       ++a+++++ a++v + +kek ++ +++ +aFD D+vl+  + 
      EEA20330.1 115 SAKAAVSRELMASQVQDMAKEKVAAAKNMAFAFDIDGVLAHGNQ 158
                     56899***********9999999****************98665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (498 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       488  (0.0272185); expected 358.6 (0.02)
Passed bias filter:                      460  (0.0256568); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 3209.40
//
Query:       EEA20331.1  [L=622]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (622 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1094  (0.0610185); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.64u 0.28s 00:00:00.92 Elapsed: 00:00:00.47
# Mc/sec: 4016.59
//
Query:       EEA20332.1  [L=176]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (176 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       269  (0.0150036); expected 358.6 (0.02)
Passed bias filter:                      230  (0.0128284); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.39u 0.29s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 1223.85
//
Query:       EEA20333.1  [L=303]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    0.00017   22.3  10.1    0.00017   22.3  10.1    4.8  4  SUZ           SUZ domain
  ------ inclusion threshold ------
        0.3   11.0  10.5        4.5    7.1   5.7    2.3  2  eIF3_subunit  Translation initiation factor eIF3 subunit


Domain annotation for each model (and alignments):
>> SUZ  SUZ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.4      0.41   3.6e+03      21      44 ..      23      45 ..      17      48 .. 0.61
   2 !   22.3  10.1   1.8e-08   0.00017      35      57 .]     115     163 ..      79     163 .. 0.58
   3 ?   -2.5   0.5       1.1   9.4e+03      15      28 ..     168     181 ..     164     187 .. 0.42
   4 ?   -3.5   5.4         2   1.8e+04      31      31 ..     222     222 ..     194     283 .. 0.66

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.41
         SUZ 21 rgssgasssesssssktleEREae 44
                + +++++ ++ ss+  t  +R a+
  EEA20333.1 23 SDAANTPPKKVSSK-VTKAQRRAA 45
                33444444556666.787787775 PP

  == domain 2  score: 22.3 bits;  conditional E-value: 1.8e-08
         SUZ  35 s..........................ktleEREaeYaeARaRIFgsfe 57 
                 +                          k +eE++++Y+eAR+R Fg+++
  EEA20333.1 115 AnisdsddenankppeltpeerqakalKDREEKQRKYEEARERLFGNSS 163
                 02233333334555566666667789********************985 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 1.1
         SUZ  15 ssssssrgssgass 28 
                 s++ss +g++++s 
  EEA20333.1 168 SGASSPGGTPPPSR 181
                 33333334333333 PP

  == domain 4  score: -3.5 bits;  conditional E-value: 2
         SUZ  31 s 31 
                 +
  EEA20333.1 222 K 222
                 2 PP

>> eIF3_subunit  Translation initiation factor eIF3 subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   5.7    0.0005       4.5      29      91 ..       4      56 ..       2      71 .. 0.65
   2 ?    6.2   0.2   0.00094       8.4      84     122 ..     122     160 ..      96     187 .. 0.62

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0005
  eIF3_subunit 29 ededvkdswdaeeeeeeekekakkaaeakakaakakkkkskkqkiaeke..errkaeeeeaeeee 91
                  e+++v d w+a+ e+ ++k  a+++       +k++ k +k+q+ a +   +r       +  ee
    EEA20333.1  4 EQNNVPDAWEADWESLADKSDAANTP-----PKKVSSKVTKAQRRAAQAefNR-------KLWEE 56
                  5679************9888886665.....4455666666666665552212.......22222 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.00094
  eIF3_subunit  84 eeeaeeeeeleeedeaarkerlrkaeeesDlknaad.lFG 122
                   +e+a++  el++e++ + k+++ ++e++  ++ a++ lFG
    EEA20333.1 122 DENANKPPELTPEER-QAKALKDREEKQRKYEEARErLFG 160
                   233344444444443.233333333444444444444555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (303 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1076  (0.0600145); expected 358.6 (0.02)
Passed bias filter:                      403  (0.0224776); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.69u 0.37s 00:00:01.06 Elapsed: 00:00:00.59
# Mc/sec: 1551.91
//
Query:       EEA20334.1  [L=265]
Description: glutathione transferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      4e-21   75.2   0.0      7e-21   74.4   0.0    1.3  1  GST_N_3       Glutathione S-transferase, N-terminal domain
    2.9e-17   62.7   0.0    5.1e-17   61.9   0.0    1.4  1  GST_N_2       Glutathione S-transferase, N-terminal domain
    1.1e-10   41.7   0.0    1.7e-10   41.1   0.0    1.3  1  GST_N         Glutathione S-transferase, N-terminal domain
    4.6e-06   26.6   0.0    9.3e-06   25.6   0.0    1.6  1  GST_C_2       Glutathione S-transferase, C-terminal domain
    0.00013   22.5   0.0    0.00022   21.8   0.0    1.3  1  GST_C_5       Glutathione S-transferase, C-terminal domain
     0.0041   17.3   0.0      0.008   16.3   0.0    1.5  1  GST_C_3       Glutathione S-transferase, C-terminal domain
  ------ inclusion threshold ------
      0.013   15.7   0.0      0.033   14.4   0.0    1.7  1  Glutaredoxin  Glutaredoxin


Domain annotation for each model (and alignments):
>> GST_N_3  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.4   0.0   2.7e-24     7e-21       1      74 [.      37     110 ..      37     111 .. 0.97

  Alignments for each domain:
  == domain 1  score: 74.4 bits;  conditional E-value: 2.7e-24
                 EES-TTSHHHHHHHHHHHHHT--EEEE---TTTTHHHHHHH-TT--SSEEETTS-EEESHHHHHHHHHHHH-GG CS
     GST_N_3   1 LygfpaSpyarrvrlaLnekglpvevvevtpgehdeellaknplgkvPvLeddgealtdSlaIidyLeelypgp 74 
                 L+g+ ++p+++rv++aL+ kg+p+++ ev+p ++++ella+np+g +P+L +++  +++S+++++yL++l +g 
  EEA20334.1  37 LFGSCFCPFVQRVWIALEAKGIPYQYIEVDPYDKPPELLAINPRGLIPALLHGNWGCYESTVLLEYLDDLDEGT 110
                 89*******************************************************************99876 PP

>> GST_N_2  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.9   0.0     2e-20   5.1e-17       1      69 [.      42     105 ..      42     106 .. 0.95

  Alignments for each domain:
  == domain 1  score: 61.9 bits;  conditional E-value: 2e-20
                 S-HHHHHHHHHHHHCT--EEEEEEH...-TTSHHHHHHHHCTTTSSSEEE-CTTEEEESHHHHHHHHHH CS
     GST_N_2   1 aCPwahRvlialalkglediisvvvlepkgfekseefprlnprgtVPvLwdkdgqvineSseIlrylet 69 
                 +CP+++Rv+ial+ kg+++++++v    ++++k++e++++nprg +P+L + ++   +eS+++l+yl++
  EEA20334.1  42 FCPFVQRVWIALEAKGIPYQYIEV----DPYDKPPELLAINPRGLIPALLH-GNWGCYESTVLLEYLDD 105
                 8***********************....99********************7.667999*********97 PP

>> GST_N  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.1   0.0   6.6e-14   1.7e-10       3      75 ..      35     104 ..      33     105 .. 0.95

  Alignments for each domain:
  == domain 1  score: 41.1 bits;  conditional E-value: 6.6e-14
                 EEEESSSTSHTHHHHHHHHHHTT-EEEEEEECSTTTCGGCHHHHHHCTTS-SSEEEETTEEEESHHHHHHHHH CS
       GST_N   3 ltlysirgsprahrirlllaakgveyevvpldfeageekspellklnplgkvPaLedngkkltESraIleYia 75 
                 l+l++   +p++ r+ ++l+akg++y+++++d+    +k+pell +np g +PaL +++    ES++ leY++
  EEA20334.1  35 LKLFGSCFCPFVQRVWIALEAKGIPYQYIEVDP---YDKPPELLAINPRGLIPALLHGNWGCYESTVLLEYLD 104
                 89******************************9...6778*******************************98 PP

>> GST_C_2  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.0   3.6e-09   9.3e-06       7      69 .]     154     220 ..     118     220 .. 0.75

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 3.6e-09
                 HHHHCCHCHHHCTTT--.-SS.CTTCS--HHHHHHHHHHHHHHHH.HHS----..TT-HHHHHHHHH CS
     GST_C_2   7 aleqldaaldaleahLa.dspflfGdqptlaDialapflvrlraa.gpgfdir..eaypnlraWler 69 
                 + ++l++++++l +    ++pf++G   +++Di lap+++rl  +  p+  +     +++l +W+++
  EEA20334.1 154 HAAELQEDIEKLVNASHvHGPFFLGPSMSYVDIQLAPWIIRLSRVlKPYRGWTepTIGSRLGRWIQA 220
                 455666666666333222566*********************5554444455522678999999986 PP

>> GST_C_5  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   0.0   8.6e-08   0.00022      35      83 ..     157     205 ..     134     214 .. 0.83

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 8.6e-08
                 HHHHHHHHHHCCHTSSSSECCECC--HHHHHHHHHHHHHHHHCCCCCT- CS
     GST_C_5  35 dnaayledllakhqgeGPyfldkelsmadvavvPflvrlkavlsyyaGy 83 
                 +   ++e+l+ + + +GP+fl+  +s  d+ + P+++rl  vl+ y G+
  EEA20334.1 157 ELQEDIEKLVNASHVHGPFFLGPSMSYVDIQLAPWIIRLSRVLKPYRGW 205
                 33457899999999******************************99886 PP

>> GST_C_3  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   3.1e-06     0.008       9      90 ..     137     225 ..     129     234 .. 0.68

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 3.1e-06
                 CCCCSHCHHH...HHHHHHHHHHHHCHHHHHHHHHH.CHGTS.SSSTTS--HHHHHHHHHHHHHHHH.....TCCCC-..HHHHHHHHHHHTSH CS
     GST_C_3   9 kllydqkeea...ekkkefleerlpkflkyfekvlk.kkggg.ylvgdklTyADlalfqvldgleea.....ealkkf..pklkalyervearp 90 
                  ++y     +   e++ ++  +++ +  + +ek++  ++  g +++g +++y+D+ l  ++  l+++     +++++    +l ++++++e ++
  EEA20334.1 137 PSFY-----KvlmEQTPQMQAKHAAELQEDIEKLVNaSHVHGpFFLGPSMSYVDIQLAPWIIRLSRVlkpyrGWTEPTigSRLGRWIQAIEGNE 225
                 5555.....2345778888888999999999999996455555**************9999998888543332111112234556666666665 PP

>> Glutaredoxin  Glutaredoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   1.3e-05     0.033       3      34 ..      37      68 ..      35      86 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.3e-05
                  EEESTSSHHHHHHHHHHHHTTGGEEEEEGCCS CS
  Glutaredoxin  3 lftkptCpyCkkakrlLkelgvkfeeidvdkd 34
                  lf++  Cp+ +++  +L+ +g+++++i+vd  
    EEA20334.1 37 LFGSCFCPFVQRVWIALEAKGIPYQYIEVDPY 68
                  788889***********************975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (265 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       855  (0.0476881); expected 358.6 (0.02)
Passed bias filter:                      717  (0.0399911); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.67u 0.35s 00:00:01.02 Elapsed: 00:00:00.56
# Mc/sec: 1426.59
//
Query:       EEA20335.1  [L=630]
Description: hypothetical protein PMAA_041820 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (630 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       561  (0.0312901); expected 358.6 (0.02)
Passed bias filter:                      425  (0.0237046); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.69u 0.32s 00:00:01.01 Elapsed: 00:00:00.52
# Mc/sec: 3620.06
//
Query:       EEA20336.1  [L=294]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
      1e-12   47.6   5.4      5e-10   39.0   1.9    2.4  2  Hexapep_2  Hexapeptide repeat of succinyl-transferase
    1.3e-11   43.8   8.9    2.5e-09   36.5   2.4    2.6  2  Hexapep    Bacterial transferase hexapeptide (six repeats)
    1.4e-10   41.3   0.0    2.2e-10   40.6   0.0    1.3  1  Mac        Maltose acetyltransferase
  ------ inclusion threshold ------
       0.11   12.7   0.0        0.2   11.9   0.0    1.4  1  DUF525     ApaG domain


Domain annotation for each model (and alignments):
>> Hexapep_2  Hexapeptide repeat of succinyl-transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.1   0.00016      0.73       2      16 ..     194     208 ..     193     214 .. 0.83
   2 !   39.0   1.9   1.1e-13     5e-10       1      34 []     229     264 ..     229     264 .. 0.97

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00016
                 EEE-TT-EE-TT-EE CS
   Hexapep_2   2 viIGdnCliGanagi 16 
                 v IG+++liG+n +i
  EEA20336.1 194 VNIGNRVLIGPNVTI 208
                 679999999999887 PP

  == domain 2  score: 39.0 bits;  conditional E-value: 1.1e-13
                 .EEE-TT-EE-TT-EE..SEEE-TT-EE-TT-EE-S CS
   Hexapep_2   1 pviIGdnCliGanagi..GvslGdncvvgaGvvita 34 
                 pv+I+d+C iG+  +i  Gv++G+++vvgaG+++t+
  EEA20336.1 229 PVTIEDDCWIGVGTTIlpGVTIGRGSVVGAGSIVTR 264
                 8**************99*****************96 PP

>> Hexapep  Bacterial transferase hexapeptide (six repeats)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.5   0.5   8.7e-05      0.39      22      34 ..     196     208 ..     193     210 .. 0.51
   2 !   36.5   2.4   5.7e-13   2.5e-09       2      36 .]     230     264 ..     229     264 .. 0.95

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 8.7e-05
                 E-TTEEEETTEEE CS
     Hexapep  22 IGdnvkIgagvvi 34 
                 IG++v Ig++v+i
  EEA20336.1 196 IGNRVLIGPNVTI 208
                 4555555555544 PP

  == domain 2  score: 36.5 bits;  conditional E-value: 5.7e-13
                 EEEETTEEE-TTEEEETTEEE-TTEEEETTEEEES CS
     Hexapep   2 tvIGsnvlIgpfaviggnVkIGdnvkIgagvvigg 36 
                 ++I+++++Ig +++i+++V+IG+++++gag+ +++
  EEA20336.1 230 VTIEDDCWIGVGTTILPGVTIGRGSVVGAGSIVTR 264
                 79*****************************9985 PP

>> Mac  Maltose acetyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.6   0.0   4.9e-14   2.2e-10       1      53 []      91     157 ..      91     157 .. 0.89

  Alignments for each domain:
  == domain 1  score: 40.6 bits;  conditional E-value: 4.9e-14
                 HHHTTS-BETTTSHHHHHHHHHHHHHHHHHHTS..............TTT-HHHHHHHHHHHSSBES CS
         Mac   1 KMlaGelYdafsDpeLvaeRlrarelcrryNqt..............rpsdkdeRrelLrellGsvG 53 
                 KM+a ++++  s+p L+a++l ar++c+ryN +              +  +++eR++lLr+  G+vG
  EEA20336.1  91 KMIAELPFRVISCPLLQAKKLEARRFCARYNVDdeilrddtlplhelFMGLRKERERLLRTVVGTVG 157
                 9******************************7437777667777777777**************998 PP

>> DUF525  ApaG domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   4.5e-05       0.2       7      72 ..     112     176 ..     107     183 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 4.5e-05
                 TB--EEEEEEEEEEE-SSS-EEEEEEEEEEEETTS-.EEEEEEESBTTB--EE-TTEEEEEEEEEEE CS
      DUF525   7 eeekyvfaYsirieneseesvqLlsRhweitdadgk.veevegeGvvGeqPlLepgesFeYtSgvsl 72 
                 e+++++ +Y++  e   ++++ L++  +  ++++++  ++v   G vG+ P++ep  +F+Y + ++l
  EEA20336.1 112 EARRFCARYNVDDEILRDDTLPLHELFMGLRKERERlLRTV--VGTVGQGPVIEPPFNFQYGCNITL 176
                 56677778888888888888888888888888888766666..799***************999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (294 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       470  (0.0262145); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2110.73
//
Query:       EEA20337.1  [L=412]
Description: ATP binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    5.5e-72  242.4   0.0    7.3e-72  242.0   0.0    1.1  1  ATP_bind_1   Conserved hypothetical ATP binding protein
    2.1e-05   24.1   0.0     0.0023   17.5   0.0    2.6  2  GTP_EFTU     Elongation factor Tu GTP binding domain
    5.8e-05   22.2   0.0      0.049   12.6   0.0    2.3  2  MeaB         Methylmalonyl Co-A mutase-associated GTPase MeaB
    0.00051   19.8   0.0      0.001   18.8   0.0    1.5  1  AAA_24       AAA domain
    0.00075   19.6   0.0      0.006   16.6   0.0    2.2  1  MMR_HSR1     50S ribosome-binding GTPase
     0.0016   17.7   0.0      0.047   12.8   0.0    2.3  2  G-alpha      G-protein alpha subunit
     0.0022   17.9   0.0      0.013   15.5   0.0    2.1  2  NACHT        NACHT domain
     0.0037   17.0   0.1      0.016   15.0   0.0    2.0  2  PRK          Phosphoribulokinase / Uridine kinase family
     0.0039   17.5   0.0       0.01   16.1   0.0    1.8  1  AAA_22       AAA domain
      0.004   16.7   0.0       0.11   12.1   0.0    2.5  3  FeoB_N       Ferrous iron transport protein B
     0.0056   16.3   0.0      0.017   14.7   0.0    1.8  2  SRP54        SRP54-type protein, GTPase domain
     0.0057   17.1   0.0      0.014   15.8   0.0    1.7  1  AAA_16       AAA ATPase domain
     0.0064   15.7   0.0      0.012   14.8   0.0    1.4  1  NB-ARC       NB-ARC domain
     0.0077   15.7   0.0        4.2    6.8   0.0    3.1  3  Arf          ADP-ribosylation factor family
     0.0089   16.2   0.0       0.02   15.1   0.0    1.7  1  AAA_33       AAA domain
  ------ inclusion threshold ------
      0.016   15.4   0.0        1.8    8.8   0.0    2.4  2  Roc          Ras of Complex, Roc, domain of DAPkinase
      0.016   14.9   0.0      0.028   14.2   0.0    1.3  1  AAA_30       AAA domain
      0.017   14.7   0.1        1.1    8.9   0.0    2.3  2  cobW         CobW/HypB/UreG, nucleotide-binding domain
      0.024   14.4   0.0        0.1   12.4   0.0    1.9  2  CLP1_P       mRNA cleavage and polyadenylation factor CLP1 P-
      0.025   14.1   0.0      0.046   13.2   0.0    1.4  1  AAA_7        P-loop containing dynein motor region
      0.026   13.8   0.0      0.047   13.0   0.0    1.4  1  Zeta_toxin   Zeta toxin
      0.026   14.4   0.1          8    6.3   0.0    3.0  3  RsgA_GTPase  RsgA GTPase
       0.04   13.7   0.0       0.43   10.3   0.0    2.5  3  PduV-EutP    Ethanolamine utilisation - propanediol utilisati
      0.088   12.7   0.0        0.2   11.5   0.0    1.6  1  APS_kinase   Adenylylsulphate kinase
        0.2   11.1   0.0       0.69    9.3   0.0    1.8  2  Pox_A32      Poxvirus A32 protein


Domain annotation for each model (and alignments):
>> ATP_bind_1  Conserved hypothetical ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  242.0   0.0     1e-74   7.3e-72       1     239 [.      22     288 ..      22     290 .. 0.94

  Alignments for each domain:
  == domain 1  score: 242.0 bits;  conditional E-value: 1e-74
  ATP_bind_1   1 vvGpaGsGKttfvgalseilelrgrsvavvNLDPAaeelpYeaavdirelitledvmedlglgpngalvvaleflresldwldeel.........ekee 90 
                 +vG+aGsGKttf+++++++l+++ ++++v+NLDPA++++p+e ++dir+ i++++vm++++lgpng++ ++l+++++++d++   l             
  EEA20337.1  22 CVGMAGSGKTTFMQRINSYLHSQRKTPYVLNLDPAVHSVPFESNIDIRDSINYKEVMKQYNLGPNGGILTSLNLFATKVDQIIGLLekrtapvdpA--- 117
                 59********************************************************************************88884444555541... PP

  ATP_bind_1  91 dd.......yllfDtPGQielfthseslakiveeLesefalvvvyLvDsqrltdptkfisgllsalsamlrlelPhvvvlnkfDllkeklekeleffed 182
                  +       ++l+DtPGQie+f +s+s+++++e+L+s+f++v+ y++D++r +++++f+s++l+a+s++++++lP++ v+nk+D+ +  +e++ e+++d
  EEA20337.1 118 -NpsgrpikHILVDTPGQIEVFVWSASGSILLETLASSFPTVIAYVIDTPRTSSTSTFMSNMLYACSILYKTKLPMILVFNKTDVQD--AEFAKEWMTD 213
                 .03333333****************************************************************************66..********** PP

  ATP_bind_1 183 vealslllekee..................ekykklaeaiaelleefalvlrflplssekeesiedllslideal 239
                 ++a++++l +ee                  +++ +l ++++ +leef+++l+++ +ss ++++i++++s+++e+ 
  EEA20337.1 214 FDAFQAALRQEEdagafgaeggsggfgagsGYMGSLLNSMSLMLEEFYRHLSVVAVSSMTGDGIDEFFSAVEEKR 288
                 *******999999**********************************************************9976 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.0     0.056        40       6      32 ..      20      46 ..      16      59 .. 0.85
   2 !   17.5   0.0   3.2e-06    0.0023     107     190 ..     174     286 ..     109     290 .. 0.68

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.056
                EEEEESTTSSHHHHHHHHHHHTTSSCH CS
    GTP_EFTU  6 igiighvDhGKtTLtdrLlyktgaisk 32
                i+ +g   +GKtT++ r+  +++  +k
  EEA20337.1 20 IVCVGMAGSGKTTFMQRINSYLHSQRK 46
                67788999**********999887665 PP

  == domain 2  score: 17.5 bits;  conditional E-value: 3.2e-06
                 STHHHHHHHHHHHHTTTEEEEEEESCGSTHHHHHHHHHHHHHHHHHH.............HHHHHHHHHTTT..........................T CS
    GTP_EFTU 107 vepqteevlrlalkegvpiivfiNKmDrlkaelkeiveevkqklsrk.............eeklekygekge..........................k 166
                  +++      ++ k ++p+i++ NK D  +ae+ +   +  + +++                                                    +
  EEA20337.1 174 FMSNMLYACSILYKTKLPMILVFNKTDVQDAEFAKEWMTDFDAFQAAlrqeedagafgaeG----------GsggfgagsgymgsllnsmslmleefyR 262
                 6666666778889999*************99998877777667755544444444444440..........1555555555555566666666666668 PP

                 TEEEEEEBTTTTBTHHHHHHHHHH CS
    GTP_EFTU 167 evpvvfgSalkgegvktllealve 190
                   +vv +S+++g+g++++++a+ e
  EEA20337.1 263 HLSVVAVSSMTGDGIDEFFSAVEE 286
                 89*****************99976 PP

>> MeaB  Methylmalonyl Co-A mutase-associated GTPase MeaB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.2   0.0     0.003       2.2      32      68 ..      20      56 ..       7      62 .. 0.87
   2 !   12.6   0.0   6.9e-05     0.049     171     248 ..     193     309 ..     188     326 .. 0.75

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.003
                EEEEE-TTSSHHHHHHHHHHHHHCTT--EEEEEE--- CS
        MeaB 32 vGltGvPGaGkstlvealglelrrrGkrvavlavDPs 68
                +   G+ G+Gk t+++++   l ++ k   vl +DP+
  EEA20337.1 20 IVCVGMAGSGKTTFMQRINSYLHSQRKTPYVLNLDPA 56
                445799*****************************97 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 6.9e-05
                 EEEEE---HHHHHHHHHHHHHHHHHCST.....................................TBTTB--EEEEEBCCCTBSHHHHHHHHHHHHHHH CS
        MeaB 171 iivvnkaDkkeaekaarelraaleleee.....................................kekeWrpkvlktsavegeGidelvdaieehrevl 232
                 i+v nk+D ++ae a+++++     +                                       +e   +  v+ +s+++g+Gide+++a+ee r+  
  EEA20337.1 193 ILVFNKTDVQDAEFAKEWMTDFDAFQAAlrqeedagafgaeggsggfgagsgymgsllnsmslmlEEFYRHLSVVAVSSMTGDGIDEFFSAVEEKRQEF 291
                 78999999999999998876544444444456679999999999999999999999999999875455556789**********************999 PP

                 HHTTHHH..HHHHHHHHH CS
        MeaB 233 kktGlle..krrrerake 248
                 ++  + e  ++++era++
  EEA20337.1 292 ERDYRPEleRKKNERAEQ 309
                 887654410444444333 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.0   1.5e-06     0.001       3      79 ..      18     137 ..      16     144 .. 0.81

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 1.5e-06
      AAA_24   3 lkiliyGpsgiGKTtlakel.......gpkplfidtekGlksldadkfpdie...swedfldevvel................................ 59 
                 + i+++G +g+GKTt++ ++        ++p +++++  ++s+ +    di+   ++++++++++                                  
  EEA20337.1  18 VAIVCVGMAGSGKTTFMQRInsylhsqRKTPYVLNLDPAVHSVPFESNIDIRdsiNYKEVMKQYNLGpnggiltslnlfatkvdqiigllekrtapvdp 116
                 6799**********************99***********************988866666666655577777777777777777778888888888888 PP

      AAA_24  60 .aaeladyktlviDtidelee 79 
                  +   +++k + +Dt +++e 
  EEA20337.1 117 aNPSGRPIKHILVDTPGQIEV 137
                 877788888888888777765 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   8.4e-06     0.006       2     114 .]      20     198 ..      19     198 .. 0.66

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 8.4e-06
                 EEEEESTTSSHHHHHHHHHTSTEEESSST.TSSSSEEEEEEEETTEE.................................................... CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltgekaivsdkp.gtTrdinegrvklkgke.................................................... 47 
                 +++vG+  +GK+t+++++        ++p    +d+  + v ++  +                                                    
  EEA20337.1  20 IVCVGMAGSGKTTFMQRINSYLHSQRKTPyVLNLDPAVHSVPFES-Nidirdsinykevmkqynlgpnggiltslnlfatkvdqiigllekrtapvdpa 117
                 7899*************9864333333332334555555554221.11233344444556677788888899999999999999999999999999999 PP

                 ........EEEEECGGCSS...HHHHHHHHHHHHHHHHCTSEEEEEEETT....TTCSHHHHHHHHHHHHH......TTSEEEEEEES CS
    MMR_HSR1  48 ........ielvDtpGlie...gaseekglgkaflaleeadlillvvdas....eeklkpldeeleellee......akkplilvlnk 114
                          +lvDtpG ie    + ++  l +++++     +i++v+d      +         + ++l        +k p+ilv+nk
  EEA20337.1 118 npsgrpikHILVDTPGQIEvfvWSASGSILLETLAS-SFPTVIAYVIDTPrtssT------STFMSNMLYAcsilykTKLPMILVFNK 198
                 999999999*******87655433344445555554.3359*******5544332......3444444333444444999*******8 PP

>> G-alpha  G-protein alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.8   0.0   6.6e-05     0.047      14      47 ..       8      42 ..       2      66 .. 0.82
   2 ?    2.3   0.0       0.1        74     268     281 ..     188     201 ..     172     224 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 6.6e-05
                XXXXXXE..EEEEEEEESTTSSHHHHHHHHH.HHC CS
     G-alpha 14 erkarkkkrevkllllGqseSGKsTilkqlk.lly 47
                e  a +++++v ++++G ++SGK+T+++ +   l+
  EEA20337.1  8 EAPAGESASPVAIVCVGMAGSGKTTFMQRINsYLH 42
                5566667889******************9984444 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.1
                 TTSEEEEEEE-HHH CS
     G-alpha 268 kntpiiLflnKlDi 281
                  + p+iL++nK+D+
  EEA20337.1 188 TKLPMILVFNKTDV 201
                 5789*********7 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   1.7e-05     0.013       3      28 ..      20      45 ..      18      57 .. 0.84
   2 ?   -0.9   0.0       1.9   1.3e+03     143     161 ..     265     283 ..     249     295 .. 0.58

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1.7e-05
                EEEEC-TTTCHHHHHHHHHHHHCTS- CS
       NACHT  3 vilqGeaGsGKTtLlqklalawaegk 28
                ++  G aGsGKTt++q++ + + +++
  EEA20337.1 20 IVCVGMAGSGKTTFMQRINSYLHSQR 45
                6778**************98887665 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 1.9
                 ..EEEE--TCCHHHHHHHH CS
       NACHT 143 ivlevegfsesrrkqlvrk 161
                  v++v +++ + ++++++ 
  EEA20337.1 265 SVVAVSSMTGDGIDEFFSA 283
                 5555555555555555543 PP

>> PRK  Phosphoribulokinase / Uridine kinase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   2.2e-05     0.016       4      54 ..      22      72 ..      19      87 .. 0.85
   2 ?   -1.7   0.1       2.8     2e+03      40      84 ..     287     331 ..     252     334 .. 0.70

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 2.2e-05
         PRK  4 vagsSGaGkttvarklekifgrekvkaaeiegdsflrldraekdleleerk 54
                  g  G+Gktt+++++++ +  + +++ + ++d  +  + +e ++ +++  
  EEA20337.1 22 CVGMAGSGKTTFMQRINSYLHSQRKTPYVLNLDPAVHSVPFESNIDIRDSI 72
                56899***********************99999999999999999888765 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 2.8
         PRK  40 rldraekdleleerkrakekevsflspeandfdllyevlkelkeg 84 
                 + +++e d+++e +++++e+  ++ + + +++++l + +  ++ g
  EEA20337.1 287 KRQEFERDYRPELERKKNERAEQATKRRDIELGKLMKDMAVMNRG 331
                 445688888888888888888888888888888888777666655 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0   1.5e-05      0.01       8      38 ..      20      53 ..      16     131 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 1.5e-05
      AAA_22  8 lvvtGesGtGKTtllrrlleqldeeakaee...e 38
                +v++G +G+GKTt ++r+ + l+ + k  +    
  EEA20337.1 20 IVCVGMAGSGKTTFMQRINSYLHSQRKTPYvlnL 53
                89******************99988777667752 PP

>> FeoB_N  Ferrous iron transport protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0      0.24   1.7e+02       2      20 ..      19      37 ..      18      43 .. 0.87
   2 !   12.1   0.0   0.00015      0.11      48     120 ..     125     204 ..      85     222 .. 0.84
   3 ?   -2.4   0.0       4.1   2.9e+03     136     155 ..     264     283 ..     257     284 .. 0.85

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.24
                EEEEEESTTSSHHHHHHHH CS
      FeoB_N  2 tvalvGnpnvGkttlfnal 20
                 +++vG   +Gktt++ ++
  EEA20337.1 19 AIVCVGMAGSGKTTFMQRI 37
                5899***********9987 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 0.00015
                 EEEEEE----SSSSSSSHHHHHHHHHHHCTSSSEEEEEEE.......GGGHHHHHHHHHHHHHTTSSEEEEEETHHHHHH CS
      FeoB_N  48 eveivDlPGiYslsayseeekvardflleeepdvvvnvvd.......atnlernLyLtlqllelgvpvvlalnmideaek 120
                 +  +vD PG  ++   s   ++  ++l+++ p v+  v+d       +t +   Ly    l  +++p++l++n++d+ ++
  EEA20337.1 125 KHILVDTPGQIEVFVWSASGSILLETLASSFPTVIAYVIDtprtsstSTFMSNMLYACSILYKTKLPMILVFNKTDVQDA 204
                 5579************************************4433333345778899999999*************98765 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 4.1
                 S-EEEEBTTTTBTHHHHHHH CS
      FeoB_N 136 vpvvktsakkkegieellka 155
                 + vv++s+ +++gi+e+ +a
  EEA20337.1 264 LSVVAVSSMTGDGIDEFFSA 283
                 5799**********998765 PP

>> SRP54  SRP54-type protein, GTPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   2.4e-05     0.017       2      38 ..      18      54 ..      17      56 .. 0.90
   2 ?   -2.6   0.0       5.1   3.7e+03      84      95 ..     124     135 ..     119     137 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 2.4e-05
                EEEEEEESTTSSHHHHHHHHHHHHHHTTS-EEEEEES CS
       SRP54  2 nvillvGlqGaGKTttlaKLaallkkegkkvllvaaD 38
                  i+ vG+ G+GKTt + ++  +l+++ k++ +  +D
  EEA20337.1 18 VAIVCVGMAGSGKTTFMQRINSYLHSQRKTPYVLNLD 54
                56899**********************9998887776 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 5.1
                 SSEEEEEE--SS CS
       SRP54  84 idvvlvDTaGrl 95 
                 i ++lvDT G+ 
  EEA20337.1 124 IKHILVDTPGQI 135
                 6789****9986 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0     2e-05     0.014      21      84 ..      14      80 ..       6     209 .. 0.75

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 2e-05
      AAA_16 21 sgrpelvllsGesGvGKsslvrellralekd..ggiflrgkcdqlesaipy...salaqalareellrq 84
                s +p +++++G++G+GK++ ++++  +l  +    ++l+ +   +  ++p+   + + + +  +e+++q
  EEA20337.1 14 SASPVAIVCVGMAGSGKTTFMQRINSYLHSQrkTPYVLNLDPAVH--SVPFesnIDIRDSINYKEVMKQ 80
                456699******************998877754377766666666..4555443335555555555555 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   1.7e-05     0.012      22      44 ..      19      41 ..      12      50 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 1.7e-05
                EEEEEESTTSSHHHHHHHHCCSH CS
      NB-ARC 22 vvalvGmgGvGKttlakqilnks 44
                 +  vGm+G+GKtt ++ i++ +
  EEA20337.1 19 AIVCVGMAGSGKTTFMQRINSYL 41
                57789**************9864 PP

>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.8   0.0    0.0058       4.2      15      36 ..      18      39 ..      10      83 .. 0.85
   2 ?    3.6   0.0     0.055        39      85     135 ..     159     209 ..     152     224 .. 0.69
   3 ?    1.1   0.0      0.34   2.4e+02     141     171 ..     256     284 ..     247     287 .. 0.79

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0058
                EEEEEEESTTSSHHHHHHHHHH CS
         Arf 15 lrilllGLDnaGKtTilkklkl 36
                + i+ +G+ ++GKtT ++++++
  EEA20337.1 18 VAIVCVGMAGSGKTTFMQRINS 39
                6799**************9876 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.055
                 EEEEEETT-CTTHHHHHHHHHHHCTSGCCTTSEEEEEEE-TTSTTSS-HHH CS
         Arf  85 vifvvDsadreRleeakeeLkalleeeelkevallvlaNKqDlpealseee 135
                 + +v+D+  ++  ++  +++    +     + +++++ NK D+++a  ++e
  EEA20337.1 159 IAYVIDTPRTSSTSTFMSNMLYACSILYKTKLPMILVFNKTDVQDAEFAKE 209
                 5677776544444444444444444445569999**********9977766 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.34
                 TGGGSSSSSSEEEEEEBTTTTBTHHHHHHHH CS
         Arf 141 gleelkgkrkleiqkcsavkgeglkeglewl 171
                  lee    r+l+++++s ++g+g++e ++ +
  EEA20337.1 256 MLEEFY--RHLSVVAVSSMTGDGIDEFFSAV 284
                 455554..99***************988766 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   2.8e-05      0.02       2      33 ..      20      56 ..      20     131 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 2.8e-05
      AAA_33  2 vllvGlpGsGKstlaerl.....lkklg.avllssdtl 33
                +++vG++GsGK+t+ +r+      ++ +  ++l+ d +
  EEA20337.1 20 IVCVGMAGSGKTTFMQRInsylhSQR-KtPYVLNLDPA 56
                689**************855553333.34666766654 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   0.0    0.0026       1.8       2      22 ..      20      40 ..      19      69 .. 0.83
   2 ?    4.3   0.0     0.064        46      55     119 ..     134     200 ..     111     217 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0026
                EEEESSTTSSHHHHHHCHCT- CS
         Roc  2 vvlvGdsgvGKtsllkrfved 22
                +v+vG +g+GKt++++r+ + 
  EEA20337.1 20 IVCVGMAGSGKTTFMQRINSY 40
                899*************98654 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.064
                 CEEEEEEEE-SGGCTTTT-HHHHCTSCEEEEEEE....GHHHHCHHHHHHHHHH.HCSSS-EEEEEE-TT CS
         Roc  55 kvklniWDtaGqerfrslhplylreaalailvyd....srssenlkeWlkelkk.vagkspvilvgnkiD 119
                 ++++ +W  +G    ++l++++ +      +v+d    s++s+ +++ l  ++  + +k p+ilv nk+D
  EEA20337.1 134 QIEVFVWSASGSILLETLASSFPTVI---AYVIDtprtSSTSTFMSNMLYACSIlYKTKLPMILVFNKTD 200
                 56777888888888888888887644...34444212222333344444444431456779999999998 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   3.9e-05     0.028      21      46 ..      20      45 ..       9      57 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 3.9e-05
      AAA_30 21 avltGpAGtGKttalkalreaweaag 46
                 v +G AG+GKtt ++ ++  ++++ 
  EEA20337.1 20 IVCVGMAGSGKTTFMQRINSYLHSQR 45
                6789**************98887764 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.0    0.0015       1.1       2      21 ..      19      38 ..      18      53 .. 0.78
   2 ?    3.3   0.0     0.074        53     115     160 ..     159     209 ..      97     222 .. 0.55

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0015
                EEEEEESTTCCHHHHHHHHH CS
        cobW  2 vtvltGflGsGKTtLlnhll 21
                ++v +G  GsGKTt+++++ 
  EEA20337.1 19 AIVCVGMAGSGKTTFMQRIN 38
                57889**********99986 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.074
                 EEEEEETTTH.CCHCCHHHHHHHHHHTSS.........EEEEE-HHHHCHC..HH CS
        cobW 115 vvavvDaknleaeeekieekaedqlaaad.........llvlnKtDlldeealle 160
                 + +v+D  +    ++++++ + ++l a++         +lv+nKtD+ d+e+  e
  EEA20337.1 159 IAYVIDTPR----TSSTSTFMSNMLYACSilyktklpmILVFNKTDVQDAEFAKE 209
                 445677733....344444444444444411111111157999999999996633 PP

>> CLP1_P  mRNA cleavage and polyadenylation factor CLP1 P-loop
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   0.00014       0.1       1      33 [.      24      56 ..      24      63 .. 0.91
   2 ?   -1.3   0.0       2.2   1.6e+03     104     135 ..     125     160 ..     115     177 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00014
      CLP1_P  1 GpkdsGKSTlarlLlNyalrkgrkpvyvDlDvG 33
                G   sGK+T+++ +  y+ ++ ++p +++lD+ 
  EEA20337.1 24 GMAGSGKTTFMQRINSYLHSQRKTPYVLNLDPA 56
                5678***************************96 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 2.2
      CLP1_P 104 sgliIntpGwvk....glgaellleliealepdvvv 135
                 ++++++tpG ++    ++  ++lle+++   p+v++
  EEA20337.1 125 KHILVDTPGQIEvfvwSASGSILLETLASSFPTVIA 160
                 689999999887444434445555555555555554 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   6.4e-05     0.046      35      81 ..      19      65 ..      14      79 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 6.4e-05
       AAA_7 35 pvllvGptGtGKtviikdllkkldkekylsltinfsaqtsanqlqdi 81
                 +++vG +G+GKt+ ++++ + l++++ ++ ++n+    ++  + + 
  EEA20337.1 19 AIVCVGMAGSGKTTFMQRINSYLHSQRKTPYVLNLDPAVHSVPFESN 65
                5799***************************9999888777666555 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   6.6e-05     0.047      11      45 ..      12      47 ..       2      77 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 6.6e-05
  Zeta_toxin 11 psqerPklillgGqpGAGKselaellkdele.rqgn 45
                 ++ +P++i+ +G  G+GK++ ++ ++ +l+ +++ 
  EEA20337.1 12 GESASPVAIVCVGMAGSGKTTFMQRINSYLHsQRKT 47
                45689*********************9999854444 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.0     0.039        28     102     123 ..      20      41 ..      11      54 .. 0.82
   2 ?   -2.5   0.0         6   4.3e+03     154     160 ..     127     133 ..     123     138 .. 0.80
   3 ?    6.3   0.0     0.011         8      42      75 ..     185     217 ..     156     227 .. 0.76

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.039
                  EEEECSTTSSHHHHHHHHCTT- CS
  RsgA_GTPase 102 svlvGqSGvGKStLinallpel 123
                  +v vG  G GK+t++ ++++ l
   EEA20337.1  20 IVCVGMAGSGKTTFMQRINSYL 41 
                  6889***********9999854 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 6
                  EEESS-S CS
  RsgA_GTPase 154 lliDtPG 160
                  +l+DtPG
   EEA20337.1 127 ILVDTPG 133
                  79****9 PP

  == domain 3  score: 6.3 bits;  conditional E-value: 0.011
                  HHHTT-EEEEEEE-GGG--HHHHHHHHHHHHHHT CS
  RsgA_GTPase  42 aeekgiepvivlnKiDlleeeeeleelkeeleal 75 
                  + ++++++++v+nK+D+ + e  ++e+++++ a+
   EEA20337.1 185 LYKTKLPMILVFNKTDVQDAEF-AKEWMTDFDAF 217
                  468999***********99988.88888887765 PP

>> PduV-EutP  Ethanolamine utilisation - propanediol utilisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0    0.0006      0.43       4      34 ..      20      50 ..      18      61 .. 0.83
   2 ?   -1.0   0.0       1.8   1.3e+03      65      73 ..     157     165 ..     124     215 .. 0.46
   3 ?   -1.6   0.0       2.8     2e+03     123     142 ..     266     285 ..     263     286 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.0006
   PduV-EutP  4 illiGkvgsGKttLtqalkgeelkYkktqai 34
                i+ +G  gsGKtt +q+++    + +kt ++
  EEA20337.1 20 IVCVGMAGSGKTTFMQRINSYLHSQRKTPYV 50
                7889**************9987777888665 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 1.8
   PduV-EutP  65 dvialvqda 73 
                  via v d+
  EEA20337.1 157 TVIAYVIDT 165
                 344444443 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 2.8
   PduV-EutP 123 ifevsavekegieellkyle 142
                 +  vs+++ +gi+e ++ +e
  EEA20337.1 266 VVAVSSMTGDGIDEFFSAVE 285
                 5789**********998776 PP

>> APS_kinase  Adenylylsulphate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   0.00028       0.2       3      39 ..      18      54 ..      16      64 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00028
                EEEEEESSTTSSHHHHHHHHHHHHHHTT--EEEEEHH CS
  APS_kinase  3 vvvwltGlsgsGKstianalekkLvekgisvylLdGd 39
                v +   G++gsGK+t  ++++++L++++++ y+L+ d
  EEA20337.1 18 VAIVCVGMAGSGKTTFMQRINSYLHSQRKTPYVLNLD 54
                678889************************9999765 PP

>> Pox_A32  Poxvirus A32 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.0   0.00096      0.69      12      38 ..      16      42 ..      13      62 .. 0.81
   2 ?   -1.9   0.0       2.5   1.8e+03      28     145 ..     247     268 ..     239     277 .. 0.51

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00096
     Pox_A32 12 kpFrlalvGgsGsGktvyLlsLlrtlv 38
                +p  ++ vG +GsGkt++++ + + l 
  EEA20337.1 16 SPVAIVCVGMAGSGKTTFMQRINSYLH 42
                678899************988766655 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 2.5
     Pox_A32  28 vyLlsLlrtlvkkykhifLltpvknseYdkyvwPdhinkvtseeeleYsLsatkekieklakkeknqkeaerfLlilDDlGdkqtksktLlellnvgRh 126
                   Ll+ ++ +                                                                                         
  EEA20337.1 247 GSLLNSMSLML---------------------------------------------------------------------------------------- 257
                 44444444444........................................................................................ PP

     Pox_A32 127 lnvsiilLcqtykhvpvng 145
                          + y+h+ v +
  EEA20337.1 258 --------EEFYRHLSVVA 268
                 ........44445544444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (412 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       980  (0.05466); expected 358.6 (0.02)
Passed bias filter:                      722  (0.04027); expected 358.6 (0.02)
Passed Vit filter:                       120  (0.00669307); expected 17.9 (0.001)
Passed Fwd filter:                        25  (0.00139439); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              25  [number of targets reported over threshold]
# CPU time: 0.63u 0.31s 00:00:00.94 Elapsed: 00:00:00.47
# Mc/sec: 2617.45
//
Query:       EEA20338.1  [L=695]
Description: cell cycle control protein (Cwf19), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.6e-30  103.9   0.1    2.4e-29  102.1   0.1    2.1  1  CwfJ_C_2     Protein similar to CwfJ C-terminus 2
      3e-28   98.1   0.0    8.5e-28   96.7   0.0    1.7  2  CwfJ_C_1     Protein similar to CwfJ C-terminus 1
  ------ inclusion threshold ------
       0.23   11.9   0.5         12    6.4   0.1    2.8  2  FumaraseC_C  Fumarase C C-terminus


Domain annotation for each model (and alignments):
>> CwfJ_C_2  Protein similar to CwfJ C-terminus 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.1   0.1     4e-33   2.4e-29       1      99 []     585     688 ..     585     688 .. 0.98

  Alignments for each domain:
  == domain 1  score: 102.1 bits;  conditional E-value: 4e-33
                 TT-SS-S---HHHHH.......SHHHHS-SSS--EEEEETTT-..-EEE----HHHH-TT..HHHHHHHHHTT--TTT.SS------S--H.HHHHHHH CS
    CwfJ_C_2   1 ewsqhkklidfskkr.......afrrslvknlpyfyvqfdykgekgyghviedeerfdlq..FareviaglLdlekrrkwrkpkrqskeeeekrveaFk 90 
                 ew+qh+klid+ +k+       afrr+lvk++pyf+v+f+ +g  g+ghv+ed +r+++   Fare i+g+Ldl++++ ++++ r+sk ++ +rve F+
  EEA20338.1 585 EWTQHRKLIDTLAKSkqglgkmAFRRTLVKEMPYFHVWFELDG--GLGHVVEDTHRWPRGdlFARETIGGMLDLPPDV-IKRQGRWSKGGD-RRVEPFR 679
                 8**********988899**************************..*********************************.*********888.9****** PP

                 HHHTTT--X CS
    CwfJ_C_2  91 kawkkyDwT 99 
                 k+w+k+DwT
  EEA20338.1 680 KRWRKFDWT 688
                 ********9 PP

>> CwfJ_C_1  Protein similar to CwfJ C-terminus 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0       0.7   4.2e+03      72      98 ..     331     357 ..     318     377 .. 0.77
   2 !   96.7   0.0   1.4e-31   8.5e-28       5     121 ..     454     575 ..     450     576 .. 0.92

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.7
                 HHHHHHHHHHHHHTT--EEEEEE-SSS CS
    CwfJ_C_1  72 rkfrkalvkmykkqdkdavvfEisser 98 
                 +++++a   m + ++ d+vv+ + ++r
  EEA20338.1 331 EQYNAAAGLMANRKEGDVVVLGVMENR 357
                 579999999999999999998876555 PP

  == domain 2  score: 96.7 bits;  conditional E-value: 1.4e-31
                 HHHHHHHHH-S----SS..---SS--S-B-SSEEEE---.S-SSTT-EEEEESS--SSTTSS-HHHHHHHHHHHHHHHHHHHHTT--EEEEEE-..SSS CS
    CwfJ_C_1   5 krikasldsClfClsnp..klekhlivsignkvYlalpk.gpLssgHvliipieHisallsldeevldeirkfrkalvkmykkqdkdavvfEis..ser 98 
                 +++++ ld+C +C  +   + + + ivs++ +++l+lp+  +Ls+g   i+pi+H+++l+++d+++++eir+f+k+l++my+ q++d++++E++   +r
  EEA20338.1 454 HKMNRILDNCPLCHHEDtdTPPVAPIVSLATRIFLTLPTePELSEGSATIVPIQHRTNLMECDDDEWEEIRNFMKSLTRMYHDQGRDVIFYENAahPDR 552
                 6788999******96651156789***************999***************************************************99999* PP

                 -----EEEEE--HHHHTTHHHHH CS
    CwfJ_C_1  99 svHlaiqvipvpksiskkaelyf 121
                 ++H++++ +p+p s+++++++ f
  EEA20338.1 553 KRHASLEAVPLPYSLGETSPAFF 575
                 *****************999988 PP

>> FumaraseC_C  Fumarase C C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0      0.03   1.8e+02      17      35 ..     203     221 ..     201     237 .. 0.84
   2 ?    6.4   0.1     0.002        12      12      35 ..     429     452 ..     429     461 .. 0.88

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.03
                  HHHHHHHHT--HHHHHHHT CS
  FumaraseC_C  17 IAkeAlkegktlreavlel 35 
                  + +eA ++gk++ ++++e+
   EEA20338.1 203 VYREAEEKGKKVEDVAIER 221
                  6789*************96 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.002
                  HHHHHHHHHHHHHT--HHHHHHHT CS
  FumaraseC_C  12 ekAakIAkeAlkegktlreavlel 35 
                  ++Aak+Ak+  k+  +l+  ++ +
   EEA20338.1 429 DNAAKLAKRVQKSELNLKNTAISE 452
                  79****************999864 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (695 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1313  (0.0732333); expected 358.6 (0.02)
Passed bias filter:                      428  (0.0238719); expected 358.6 (0.02)
Passed Vit filter:                        94  (0.0052429); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.85u 0.32s 00:00:01.17 Elapsed: 00:00:00.48
# Mc/sec: 4371.53
//
Query:       EEA20339.1  [L=334]
Description: glyoxylate reductase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.8e-58  195.2   0.0    7.8e-58  194.7   0.0    1.2  1  2-Hacid_dh_C   D-isomer specific 2-hydroxyacid dehydrogenase,
    1.4e-14   53.9   0.0      2e-14   53.4   0.0    1.2  1  2-Hacid_dh     D-isomer specific 2-hydroxyacid dehydrogenase,
    4.3e-05   23.7   0.2    7.2e-05   23.0   0.2    1.4  1  NAD_binding_2  NAD binding domain of 6-phosphogluconate dehyd
     0.0029   17.2   0.1     0.0049   16.4   0.1    1.3  1  IlvN           Acetohydroxy acid isomeroreductase, NADPH-bind
  ------ inclusion threshold ------
      0.062   13.2   0.0       0.26   11.1   0.0    2.0  2  Rossmann-like  Rossmann-like domain
       0.14   12.8   0.0       0.29   11.8   0.0    1.6  1  F420_oxidored  NADP oxidoreductase coenzyme F420-dependent


Domain annotation for each model (and alignments):
>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  194.7   0.0   2.6e-61   7.8e-58       2     178 .]     123     297 ..     122     297 .. 0.96

  Alignments for each domain:
  == domain 1  score: 194.7 bits;  conditional E-value: 2.6e-61
                   HHHHHHHTTHHHHHHHHHTTCC.HTTCCGSBS-GTTSEEEEES-SHHHHHHHHHHHHTT-EEEEESSSHHHHHCHHHHTCEECSHHHHHHH-SEEEE CS
  2-Hacid_dh_C   2 alllallrrlaeadeevregew.ksekallgkelsgktvGiiGlGrIGqavakrlkafgmkviaydrskkkeeeeeelgvelvsleellaesDivsl 97 
                    l++ ++r+++ + +++r+g+w  +++  lg++ +gk +Gi+G+G IG+++ k+++afgmkvi+++r++ +e+   + g+e+v+++ella+sD++sl
    EEA20339.1 123 FLIIGAIRNFNTGMHALRQGKWrGDPAPPLGHDPEGKVLGILGMGGIGRNLKKKAEAFGMKVIYHNRRQLSET--MSAGAEYVTFDELLAKSDVISL 217
                   6899******************8888899***************************************88554..6779****************** PP

                   -S--STTTTTSBSHHHHHCSTTTEEEEESS-GGGB-HHHHHHHHHTTSCCEEEES--SSSSSGTCHHHHHSTTEEE-SS-T CS
  2-Hacid_dh_C  98 hlpltpetrhlinaeelakmkkgailiNtaRGglvdeeaLleaLksgkiagaalDvfeeeplpedspllelpnviltPHia 178
                   +lpl+++t+h+i++ e++kmk+g++++NtaRG+++de+aL+eaL+sgk+  a+lDvfeeep  +   ll+ pnv+l PH++
    EEA20339.1 218 NLPLNKHTYHIIGKPEFEKMKDGVVVVNTARGAVIDEAALVEALDSGKVFSAGLDVFEEEPKIHP-GLLRNPNVMLVPHMG 297
                   **************************************************************977.99***********98 PP

>> 2-Hacid_dh  D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.4   0.0   6.6e-18     2e-14      11     133 ..      18     328 ..       6     329 .. 0.95

  Alignments for each domain:
  == domain 1  score: 53.4 bits;  conditional E-value: 6.6e-18
                 HHHHHHHTTE.EEEEESCSSHHHCHHHHTT..ESEEEE-TTS........-BSHHHHHHH.TT--EEEESSSSCTTB-HHHHHHTT..-EEEE-TTTTH CS
                 xxxxxxxxxx.xxxxxxxxxxxxxxxxxxx..xxxxxxxxxx........xxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxx RF
  2-Hacid_dh  11 elellkeegv.evevkdellteellekakd..adalivrsnt........kvtaevleal.pkLkviaragvGvDnvDldaakerG..ilVtnvpgyst 95 
                 + e l++  + ++ ++++  ++e ++++kd   d+++ +++t        ++++e+ + l ++L + a++g+G+D+vD+ a++er   i V+nvp++  
  EEA20339.1  18 TWEALSD--IaDLITTSATNRAEFIQECKDgkLDGVVAAYRTfasfsitgQIDEEIVSVLpKSLLFLAHCGAGYDQVDVHACSERTppIRVSNVPTAVD 114
                 5566666..6688888888999999999999999999999999999999************************************666*********** PP

                 HHHHHHH............................................................................................ CS
                 xxxxxxx............................................................................................ RF
  2-Hacid_dh  96 esvAElt............................................................................................ 102
                 +s+A++                                                                                             
  EEA20339.1 115 DSTADVNmfliigairnfntgmhalrqgkwrgdpapplghdpegkvlgilgmggigrnlkkkaeafgmkviyhnrrqlsetmsagaeyvtfdellaksd 213
                 *************************************************************************************************** PP

                 ....................................................................................T-BHHHHHHHHHHHH CS
                 ....................................................................................xxxxxxxxxxxxxxx RF
  2-Hacid_dh 103 ....................................................................................aaTeeaqeniaeeaa 117
                                                                                                      ++ e+q ++ e a+
  EEA20339.1 214 vislnlplnkhtyhiigkpefekmkdgvvvvntargavideaalvealdsgkvfsagldvfeeepkihpgllrnpnvmlvphmgTWSYETQTEMEEWAI 312
                 ************************************************************************************9************** PP

                 HHHHHHHTTCCGTTBC CS
                 xxxxxxxxxxxxxxxx RF
  2-Hacid_dh 118 enlvaflkgespanav 133
                  n++++++ ++++++v
  EEA20339.1 313 GNVRQAIEKGTLKSIV 328
                 **********999987 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.0   0.2   2.4e-08   7.2e-05       2     105 ..     161     262 ..     160     273 .. 0.88

  Alignments for each domain:
  == domain 1  score: 23.0 bits;  conditional E-value: 2.4e-08
                    EEEE--SHHHHHHHHHHHHTT-EEEEE-SSHHHHHHHHHTTEEE-SSHHHHHHHCSEEEE-SSSHHHHHHHHHS.HCCC--TT-EEEE-S---HHH CS
  NAD_binding_2   2 igfiGlGvMGsnmalnllkagykvavynrtkekveelvaegakaaesieelvasldvvitmvkagkavdevieg.llealkkgdilidgstssped 96 
                    +g++G+G +G+n+ ++ ++ g+kv+ +nr+  ++ e +++ga+ + +  el+a+ dv+ + ++ +k++ ++i +  +e++k g ++++++  ++ d
     EEA20339.1 161 LGILGMGGIGRNLKKKAEAFGMKVIYHNRR--QLSETMSAGAEYV-TFDELLAKSDVISLNLPLNKHTYHIIGKpEFEKMKDGVVVVNTARGAVID 253
                    699*************************98..8899999999766.578899999*******************999*********9998877777 PP

                    HHHHHHHHH CS
  NAD_binding_2  97 trelakelk 105
                       l ++l 
     EEA20339.1 254 EAALVEALD 262
                    777766665 PP

>> IlvN  Acetohydroxy acid isomeroreductase, NADPH-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.1   1.7e-06    0.0049       4      91 ..     158     243 ..     157     266 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 1.7e-06
                 TS-EEEES-SHHHHHHHHHHHHTT--EEEEE-TT-HHHHHHHHTT-EEEEHHHHHHT-SEEEE-S-HHHH.HHHHHHHTGGG--TT-EE CS
        IlvN   4 gkkiaviGyGsqGhaqalnlrdsgldvvvglregsksvkkAkeegfevltvaeavkkadvvmiliPDelq.kevyeeeiepnlkegkal 91 
                 gk + ++G+G  G++  ++    g++v++ +r++    ++ +++g e +t +e+ +k+dv+ + +P + +  +++ +   +++k+g ++
  EEA20339.1 158 GKVLGILGMGGIGRNLKKKAEAFGMKVIYHNRRQL---SETMSAGAEYVTFDELLAKSDVISLNLPLNKHtYHIIGKPEFEKMKDGVVV 243
                 78899***********************9988776...77888999********************65541466666666677777644 PP

>> Rossmann-like  Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0      0.81   2.4e+03      54      87 ..      22      54 ..      11      67 .. 0.67
   2 ?   11.1   0.0   8.8e-05      0.26      14     105 ..     162     248 ..     152     265 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.81
  Rossmann-like 54 lPdvpvlevedvaaraellllavPdaelpglvkg 87
                   l d++ l     ++rae+ +    d +l g+v+ 
     EEA20339.1 22 LSDIADLITTSATNRAEF-IQECKDGKLDGVVAA 54
                   556666666666777775.456778888888875 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 8.8e-05
  Rossmann-like  14 GiisaGrvGtalgaaleraghvvvgisaisaasreraerrlPdvpvlevedvaaraellllavPdaelpglvkglaatgavraGtivahtsg 105
                    Gi++ G +G  l +  e      +g++ i +  r+++e++  + + ++ +++ a+++++ l +P  + +  + g  + + +++G +v+ t+ 
     EEA20339.1 162 GILGMGGIGRNLKKKAE-----AFGMKVIYHNRRQLSETMSAGAEYVTFDELLAKSDVISLNLPLNKHTYHIIGKPEFEKMKDGVVVVNTAR 248
                    77777777776655433.....57888899*********************************************************99864 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   9.6e-05      0.29       2      75 ..     161     225 ..     160     249 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 9.6e-05
                    EEEETTSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC-EEECECHHHHHHH-SEEEE-S-HHHHH CS
  F420_oxidored   2 igiiGaGnmgealasgllaagaqpheivvansrnpekaeelaeelgvkvtavdneeaaeeadvvvlavkpedve 75 
                    +gi+G+G +g+ l +++ a g    +++         +++l e+++++++ v+  e+++++dv+ l ++ ++++
     EEA20339.1 161 LGILGMGGIGRNLKKKAEAFG---MKVIYH------NRRQLSETMSAGAEYVTFDELLAKSDVISLNLPLNKHT 225
                    79*******************...999944......4455667777777778899999999*999999887654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (334 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       483  (0.0269396); expected 358.6 (0.02)
Passed bias filter:                      464  (0.0258799); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.47u 0.23s 00:00:00.70 Elapsed: 00:00:00.38
# Mc/sec: 2627.06
//
Query:       EEA20340.1  [L=777]
Description: C6 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-08   34.2   8.6    3.4e-08   33.5   8.6    1.3  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.5   8.6   1.9e-12   3.4e-08       1      34 [.     324     357 ..     324     361 .. 0.92

  Alignments for each domain:
  == domain 1  score: 33.5 bits;  conditional E-value: 1.9e-12
                 SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCC CS
     Zn_clus   1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfys 34 
                 ++C +Crk+++KCd+++P+C+nC+k+  eC  y+
  EEA20340.1 324 TGCLTCRKRRIKCDEGHPVCRNCVKSKRECLGYD 357
                 58****************************8765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (777 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       740  (0.0412739); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.76u 0.32s 00:00:01.08 Elapsed: 00:00:00.48
# Mc/sec: 4893.44
//
Query:       EEA20341.1  [L=289]
Description: formin binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.3e-07   31.3   0.4    2.5e-07   30.4   0.4    1.5  1  zf-U1         U1 zinc finger
  ------ inclusion threshold ------
        8.3    6.5  10.2          2    8.5   5.1    2.5  2  ABC_tran_Xtn  ABC transporter


Domain annotation for each model (and alignments):
>> zf-U1  U1 zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.4   0.4   2.8e-11   2.5e-07       2      37 ..       9      43 ..       8      44 .. 0.93

  Alignments for each domain:
  == domain 1  score: 30.4 bits;  conditional E-value: 2.8e-11
                XSEEETTTTEEESS-SHHHHHHHHTSHHHHHHHHHH CS
       zf-U1  2 pkYyCdYCdiyLthDspsvRksHngGrkHkenvkdy 37
                pkY+C+ C+iy+  D+ +   +H+++ kH+ n k++
  EEA20341.1  9 PKYWCKHCQIYI-RDTTFEKTQHEATGKHQGNLKRF 43
                9***********.8999999************9987 PP

>> ABC_tran_Xtn  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   5.1   0.00022         2      10      73 ..      35     115 ..      26     129 .. 0.81
   2 ?   -2.4   0.2      0.55     5e+03      25      36 ..     163     174 ..     158     184 .. 0.54

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00022
  ABC_tran_Xtn  10 eYkGnYseyleekeerleqqqkayekqqkeikkleefIerfraka.................kkakqaqsrekaLekleki 73 
                   + +Gn +++l+   +++e+++++ ++ ++e+++l++ +    a +                  +++ a++r+k++ +l ++
    EEA20341.1  35 KHQGNLKRFLRDIHRNKEREERDSQRTKNEVERLRNLVGGKPAGGdatrnrpsgaaaptnngPRQASAEERKKQIAQLAEM 115
                   678*********************************998888766778888888888888887777788888888888653 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.55
  ABC_tran_Xtn  25 rleqqqkayekq 36 
                   +le+++ ++e+q
    EEA20341.1 163 KLENEEDEEEAQ 174
                   334444333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (289 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1126  (0.0628033); expected 358.6 (0.02)
Passed bias filter:                      520  (0.0290033); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.47
# Mc/sec: 1858.26
//
Query:       EEA20342.1  [L=614]
Description: tubulin-specific chaperone, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.6e-20   71.7   0.1    7.7e-20   70.7   0.1    1.6  1  CAP_GLY   CAP-Gly domain
    1.1e-09   38.4  18.7      0.016   15.6   1.7    5.8  7  LRR_4     Leucine Rich repeats (2 copies)
    1.8e-08   34.0  19.1    1.5e-05   24.6   1.5    4.8  6  LRR_8     Leucine rich repeat
    7.5e-08   32.1   2.2      0.045   13.2   0.8    3.9  4  LRR_9     Leucine-rich repeat
    1.7e-06   27.6   6.8       0.76   10.0   0.1    5.9  5  LRR_6     Leucine Rich repeat
     0.0027   18.0   3.7    1.3e+02    3.8   0.0    6.7  6  LRR_1     Leucine Rich Repeat
  ------ inclusion threshold ------
      0.031   14.2   0.1      0.053   13.5   0.1    1.3  1  DUF1619   Protein of unknown function (DUF1619)


Domain annotation for each model (and alignments):
>> CAP_GLY  CAP-Gly domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.7   0.1     3e-23   7.7e-20       1      64 [.       7      73 ..       7      74 .. 0.89

  Alignments for each domain:
  == domain 1  score: 70.7 bits;  conditional E-value: 3e-23
     CAP_GLY  1 vgdrvklkegrrGvvryvGpvpfakgewvGveldep.nGkndGsvkgkrYFec...kpnrGvFvrpek 64
                +gdr +  +g  +++ry+G+v+++kg w+Gve+d+p +Gk+ G++kgkrYF+c   +p  G+Fvrp++
  EEA20342.1  7 IGDRLSF-DGAPCTIRYIGDVEGTKGDWLGVEWDDPfRGKHSGEHKGKRYFTCisnQPTAGSFVRPTR 73
                6888874.7889************************99***************4333669*****986 PP

>> LRR_4  Leucine Rich repeats (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0     0.028        72      21      36 ..     174     188 ..     166     195 .. 0.77
   2 !   12.8   0.4   4.6e-05      0.12       1      38 [.     176     216 ..     176     229 .. 0.82
   3 !    7.5   0.1    0.0023       5.8       1      30 [.     202     231 ..     202     240 .. 0.79
   4 ?    5.2   0.1     0.012        31      21      40 ..     247     265 ..     224     269 .. 0.72
   5 !   15.6   1.7   6.3e-06     0.016       3      37 ..     272     308 ..     270     313 .. 0.81
   6 !   12.8   0.1   4.9e-05      0.12       3      36 ..     323     359 ..     321     361 .. 0.82
   7 ?   -1.6   0.1       1.6   4.1e+03      22      29 ..     390     397 ..     385     403 .. 0.68

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.028
                 H-TT--EEE-.-S--- CS
       LRR_4  21 klpnLkeLdLsgNnli 36 
                  +p+ +eLdL++N li
  EEA20342.1 174 TCPKITELDLTRN-LI 188
                 59********888.65 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 4.6e-05
                 SS--EEE--SS---E-S-....HHH-TT--EEE-.-S----- CS
       LRR_4   1 pnLevLdLsnNqltdipl....leklpnLkeLdLsgNnlitd 38 
                 p+ ++LdL  N +  +      +++l++Lk+L L+gN + ++
  EEA20342.1 176 PKITELDLTRNLIYRWRDvhdiCKQLKKLKSLKLNGN-RFEK 216
                 6889*****9999998887654447*********999.5544 PP

  == domain 3  score: 7.5 bits;  conditional E-value: 0.0023
                 SS--EEE--SS---E-S-.HHH-TT--EEE- CS
       LRR_4   1 pnLevLdLsnNqltdipl.leklpnLkeLdL 30 
                 ++L++L L++N+  ++++ +  +   +eL+L
  EEA20342.1 202 KKLKSLKLNGNRFEKVQPgIV-FNGITELHL 231
                 689***********9999755.666666666 PP

  == domain 4  score: 5.2 bits;  conditional E-value: 0.012
                 H-TT--EEE-.-S-----GG CS
       LRR_4  21 klpnLkeLdLsgNnlitdld 40 
                 ++p+L++L L + n +t+++
  EEA20342.1 247 QFPDLQSL-LASSNGLTSIT 265
                 68888888.85555888875 PP

  == domain 5  score: 15.6 bits;  conditional E-value: 6.3e-06
                 --EEE--SS---E-S-HH...H-TT--EEE-.-S---- CS
       LRR_4   3 LevLdLsnNqltdiplle...klpnLkeLdLsgNnlit 37 
                 L+++ L nN  t++++l+    lpnL+ L L gN +i+
  EEA20342.1 272 LKSVVLENNDFTSLSSLKilaELPNLTRLILRGN-NID 308
                 9999************555548*******99888.443 PP

  == domain 6  score: 12.8 bits;  conditional E-value: 4.9e-05
                 --EEE--SS---E-S-HH....H-TT--EEE-.-S--- CS
       LRR_4   3 LevLdLsnNqltdiplle....klpnLkeLdLsgNnli 36 
                 L +Ld s+N++ ++ +++     +p L +L +sgN ++
  EEA20342.1 323 LSYLDVSHNKIDSWLFINdlatAFPGLDSLRISGN-PL 359
                 779**********8885566655************.54 PP

  == domain 7  score: -1.6 bits;  conditional E-value: 1.6
                 -TT--EEE CS
       LRR_4  22 lpnLkeLd 29 
                 l nL++L+
  EEA20342.1 390 LENLTSLN 397
                 66666665 PP

>> LRR_8  Leucine rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.3   3.5e-05     0.089       1      43 [.     176     220 ..     176     234 .. 0.77
   2 ?   -1.5   0.0      0.88   2.3e+03      47      61 .]     247     261 ..     243     261 .. 0.84
   3 !    9.4   5.0   0.00034      0.88       3      61 .]     251     307 ..     249     307 .. 0.78
   4 !   22.3   4.6   3.1e-08   7.9e-05       3      61 .]     272     333 ..     270     333 .. 0.90
   5 !   24.6   1.5     6e-09   1.5e-05       1      61 []     295     359 ..     295     359 .. 0.92
   6 ?   -2.6   0.1       1.9   4.7e+03      46      55 ..     388     397 ..     386     399 .. 0.61

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 3.5e-05
                 TT-SEEE-TTS--SEE-T..TSSTT-TT--EEE--SS---GGGGG CS
       LRR_8   1 pnLtsLdLsnNrltsldd..eaFkglsnLkvLdLsnNllttlspg 43 
                 p+ t+LdL++N +   +d  +  k+l++Lk+L+L+ N+ + + pg
  EEA20342.1 176 PKITELDLTRNLIYRWRDvhDICKQLKKLKSLKLNGNRFEKVQPG 220
                 567899999999877775336788899999999999999988876 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.88
                 T--S-.EEE--SS-- CS
       LRR_8  47 gLpsLrsLdLsgNrL 61 
                 ++p L+sL  s+N L
  EEA20342.1 247 QFPDLQSLLASSNGL 261
                 678999999999976 PP

  == domain 3  score: 9.4 bits;  conditional E-value: 0.00034
                 -SEEE-TTS--SEE-TTSSTT-TT--EEE--SS---G.GGGGGGTT--S-.EEE--SS-- CS
       LRR_8   3 LtsLdLsnNrltslddeaFkglsnLkvLdLsnNlltt.lspgafsgLpsLrsLdLsgNrL 61 
                 L+sL  s+N lts+  +      +Lk+  L nN  t+  s + ++ Lp+L+ L L+gN++
  EEA20342.1 251 LQSLLASSNGLTSITATLPI---ALKSVVLENNDFTSlSSLKILAELPNLTRLILRGNNI 307
                 67777777888888888777...7899999999888834568889999999999999987 PP

  == domain 4  score: 22.3 bits;  conditional E-value: 3.1e-08
                 -SEEE-TTS--SEE-TTSSTT.-TT--EEE--SS---G..GGGGGGTT--S-.EEE--SS-- CS
       LRR_8   3 LtsLdLsnNrltslddeaFkg.lsnLkvLdLsnNlltt..lspgafsgLpsLrsLdLsgNrL 61 
                 L+s++L nN +tsl+       l+nL+ L L+ N+++t   ++ +f+  + L +Ld+s+N++
  EEA20342.1 272 LKSVVLENNDFTSLSSLKILAeLPNLTRLILRGNNIDTvfKDKSTFQFSHTLSYLDVSHNKI 333
                 99************99777777****************5557789***************97 PP

  == domain 5  score: 24.6 bits;  conditional E-value: 6e-09
                 TT-SEEE-TTS--SEE..-TTSSTT-TT--EEE--SS---G..GGGGGGTT--S-.EEE--SS-- CS
       LRR_8   1 pnLtsLdLsnNrltsl..ddeaFkglsnLkvLdLsnNlltt..lspgafsgLpsLrsLdLsgNrL 61 
                 pnLt+L+L+ N++  +  d+++F+  + L +Ld s+N++++  + ++    +p L+sL +sgN+L
  EEA20342.1 295 PNLTRLILRGNNIDTVfkDKSTFQFSHTLSYLDVSHNKIDSwlFINDLATAFPGLDSLRISGNPL 359
                 79**********999955678*******************9986789999*************97 PP

  == domain 6  score: -2.6 bits;  conditional E-value: 1.9
                 TT--S-.EEE CS
       LRR_8  46 sgLpsLrsLd 55 
                 + L++L+sL+
  EEA20342.1 388 ARLENLTSLN 397
                 5566666665 PP

>> LRR_9  Leucine-rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.9   0.0    0.0016         4      81     124 ..     169     213 ..     129     220 .. 0.81
   2 !    5.1   0.1    0.0058        15      62      83 ..     200     221 ..     181     257 .. 0.86
   3 !   13.2   0.8   1.8e-05     0.045      66     125 ..     251     307 ..     244     315 .. 0.81
   4 !    8.0   0.0   0.00074       1.9      60     171 ..     317     422 ..     308     426 .. 0.75

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0016
       LRR_9  81 egleevlPnleelvltnnelqeladldPla.slkklellsllknp 124
                 +++e++ P+++el lt n + +  d++ +  +lkkl++l l  n 
  EEA20342.1 169 QKIERTCPKITELDLTRNLIYRWRDVHDICkQLKKLKSLKLNGNR 213
                 567788999999999999999999997764279999998886665 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0058
       LRR_9  62 llkrlktlllnnnrivriaegl 83 
                  lk+lk+l ln nr  ++++g+
  EEA20342.1 200 QLKKLKSLKLNGNRFEKVQPGI 221
                 699***************9987 PP

  == domain 3  score: 13.2 bits;  conditional E-value: 1.8e-05
       LRR_9  66 lktlllnnnrivriaegleevlP.nleelvltnnelqeladldPlaslkklellsllknpv 125
                 l++ll ++n ++ i+  l    P  l+++vl nn +++l+ l+ la+l++l+ l l  n +
  EEA20342.1 251 LQSLLASSNGLTSITATL----PiALKSVVLENNDFTSLSSLKILAELPNLTRLILRGNNI 307
                 566777777777666554....43589***************************9988876 PP

  == domain 4  score: 8.0 bits;  conditional E-value: 0.00074
       LRR_9  60 fPllkrlktlllnnnrivr..iaegleevlPnleelvltnnelqeladldPlaslkklellsllknpvtnkkeyrlyviyklkqlrlldfrkvklkere 156
                 f + + l  l ++ n+i      ++l+ + P l++l +++n l++ a   P      + +  l + p+t  + + l +  +l++l+ l++ k+ +++r 
  EEA20342.1 317 FQFSHTLSYLDVSHNKIDSwlFINDLATAFPGLDSLRISGNPLHDRAV-AP------MGVTGLPEKPMTVDEAFMLTL-ARLENLTSLNYSKITQQDRT 407
                 666666777777777775422457788888888888888888777553.44......455677789999999987765.69****************** PP

       LRR_9 157 eaeklfkskkgkela 171
                 + e ++ s  gkel 
  EEA20342.1 408 NGELYYLSLIGKELS 422
                 **9999998888875 PP

>> LRR_6  Leucine Rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.2   0.1    0.0049        13       2      15 ..     175     188 ..     174     188 .. 0.90
   2 ?    1.8   0.0      0.13   3.3e+02       3      15 ..     202     214 ..     200     216 .. 0.86
   3 !    7.1   0.1    0.0024       6.2       3      17 ..     295     309 ..     293     310 .. 0.89
   4 !   10.0   0.1    0.0003      0.76       2      16 ..     320     334 ..     319     335 .. 0.91
   5 ?    0.3   0.0      0.37   9.4e+02       7      18 ..     351     362 ..     348     367 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0049
       LRR_6   2 nthLteLdLsgNdI 15 
                 ++++teLdL+ N I
  EEA20342.1 175 CPKITELDLTRNLI 188
                 899*********76 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.13
       LRR_6   3 thLteLdLsgNdI 15 
                  +L++L L+gN +
  EEA20342.1 202 KKLKSLKLNGNRF 214
                 58*********76 PP

  == domain 3  score: 7.1 bits;  conditional E-value: 0.0024
       LRR_6   3 thLteLdLsgNdIgD 17 
                 ++Lt L L+gN+I+ 
  EEA20342.1 295 PNLTRLILRGNNIDT 309
                 79***********86 PP

  == domain 4  score: 10.0 bits;  conditional E-value: 0.0003
       LRR_6   2 nthLteLdLsgNdIg 16 
                 +++L +Ld+s+N+I+
  EEA20342.1 320 SHTLSYLDVSHNKID 334
                 689**********97 PP

  == domain 5  score: 0.3 bits;  conditional E-value: 0.37
       LRR_6   7 eLdLsgNdIgDe 18 
                 +L +sgN + D 
  EEA20342.1 351 SLRISGNPLHDR 362
                 799*****9985 PP

>> LRR_1  Leucine Rich Repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.0      0.82   2.1e+03       2      12 ..     178     188 ..     177     200 .. 0.80
   2 ?    3.8   0.0      0.05   1.3e+02       1      16 [.     203     218 ..     203     232 .. 0.81
   3 ?    0.5   0.0      0.58   1.5e+03       2      17 ..     272     287 ..     271     290 .. 0.83
   4 ?    2.4   0.0      0.14   3.6e+02       1      13 [.     296     308 ..     296     320 .. 0.78
   5 ?    2.3   0.0      0.15   3.9e+02       2      13 ..     323     335 ..     322     347 .. 0.77
   6 ?    0.9   0.0      0.44   1.1e+03       3      12 ..     350     359 ..     348     374 .. 0.77

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.82
       LRR_1   2 LrhLdLsnnpl 12 
                  ++LdL++n +
  EEA20342.1 178 ITELDLTRNLI 188
                 689****9975 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.05
       LRR_1   1 nLrhLdLsnnpllglp 16 
                 +L++L L++n+++  +
  EEA20342.1 203 KLKSLKLNGNRFEKVQ 218
                 7**********95444 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.58
       LRR_1   2 LrhLdLsnnpllglpp 17 
                 L++  L+nn +++l++
  EEA20342.1 272 LKSVVLENNDFTSLSS 287
                 89999*****987765 PP

  == domain 4  score: 2.4 bits;  conditional E-value: 0.14
       LRR_1   1 nLrhLdLsnnpll 13 
                 nL++L L++n+++
  EEA20342.1 296 NLTRLILRGNNID 308
                 8*********983 PP

  == domain 5  score: 2.3 bits;  conditional E-value: 0.15
       LRR_1   2 LrhLdLsnnpl.l 13 
                 L +Ld+s+n + +
  EEA20342.1 323 LSYLDVSHNKIdS 335
                 789******9843 PP

  == domain 6  score: 0.9 bits;  conditional E-value: 0.44
       LRR_1   3 rhLdLsnnpl 12 
                  +L +s+npl
  EEA20342.1 350 DSLRISGNPL 359
                 5899*****9 PP

>> DUF1619  Protein of unknown function (DUF1619)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.1   2.1e-05     0.053      66     136 ..      49     118 ..      39     135 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.1e-05
     DUF1619  66 eevnpdlf.Cvqssnnssplgsfysaaksvrtesnfeaslakklkeaafkkesekssse.sskYkvgdpiqtv 136
                 e++ +++f C+  s n++++gsf+++++ ++ +++f ++l++k+ ++++++  ++++ + +++++ +d+iq+ 
  EEA20342.1  49 EHKGKRYFtCI--S-NQPTAGSFVRPTRPIDIPQSFLEALHQKYASEFEEEIAKRKAVNnDAEFQMNDTIQFN 118
                 567788899*9..3.4455699**********************8888655555444448**********986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (614 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       627  (0.0349713); expected 358.6 (0.02)
Passed bias filter:                      503  (0.0280551); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 4113.64
//
Query:       EEA20343.1  [L=234]
Description: splicing factor 3a subunit 2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-36  124.9   0.0    1.9e-36  124.3   0.0    1.3  1  SF3A2     Pre-mRNA-splicing factor SF3a complex subunit 2 (Pr
    1.8e-05   24.9   1.7      2e-05   24.8   0.5    1.7  2  zf-met    Zinc-finger of C2H2 type
  ------ inclusion threshold ------
      0.048   13.2   1.5       0.11   12.1   1.5    1.6  1  PRP4      pre-mRNA processing factor 4 (PRP4) like


Domain annotation for each model (and alignments):
>> SF3A2  Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  124.3   0.0   3.2e-40   1.9e-36       1      96 []     115     210 ..     115     210 .. 0.99

  Alignments for each domain:
  == domain 1  score: 124.3 bits;  conditional E-value: 3.2e-40
       SF3A2   1 igrPgykvtkvrdpeteqvgllvevkypeikeevkPlhrimsaleqkleekpdkkvqyLliaaePYetiafkipskeidksedklwtfwdkdkkey 96 
                 igrPgyk+tk+rdp t+q gll++++y+ei+  v P++r+msa+eqk++++pdk++qyLl+aaePY+t++fk++++eid++e+++wt +d+d+ke+
  EEA20343.1 115 IGRPGYKITKTRDPMTRQLGLLFQLQYQEITPGVVPRVRFMSAFEQKVDDPPDKNFQYLLVAAEPYQTCGFKLQAREIDRREGRYWTWFDEDSKEF 210
                 8*********************************************************************************************98 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       1.9   1.1e+04      16      22 ..      47      53 ..      46      53 .. 0.79
   2 !   24.8   0.5   3.3e-09     2e-05       1      25 []      54      78 ..      54      78 .. 0.98

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 1.9
      zf-met 16 lksHlqG 22
                +k+Hl +
  EEA20343.1 47 FKNHLGS 53
                799*965 PP

  == domain 2  score: 24.8 bits;  conditional E-value: 3.3e-09
      zf-met  1 fyCelCnvtfnsesqlksHlqGKkH 25
                f+C lC +++++ +++ +H qG+kH
  EEA20343.1 54 FECRLCLTVHQNDGSYLAHTQGRKH 78
                89*********************** PP

>> PRP4  pre-mRNA processing factor 4 (PRP4) like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   1.5   1.8e-05      0.11      18      29 .]      22      33 ..      22      33 .. 0.94

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 1.8e-05
        PRP4 18 thadRreRLrkL 29
                t+adRreRLrkL
  EEA20343.1 22 TNADRRERLRKL 33
                79*********8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (234 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       454  (0.0253221); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.30s 00:00:00.78 Elapsed: 00:00:00.47
# Mc/sec: 1496.98
//
Query:       EEA20344.1  [L=638]
Description: serine/threonine protein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.9e-55  185.7   0.0    1.7e-53  181.7   0.0    2.2  1  Pkinase         Protein kinase domain
      8e-25   87.6   0.5    1.8e-19   70.0   0.1    2.2  2  Pkinase_Tyr     Protein tyrosine kinase
    4.9e-06   25.7   0.0    7.1e-06   25.2   0.0    1.2  1  Haspin_kinase   Haspin like kinase domain
    4.6e-05   23.5   3.2      0.021   14.8   0.1    3.2  3  APH             Phosphotransferase enzyme family
    0.00028   20.3   0.0    0.00066   19.1   0.0    1.6  1  Kdo             Lipopolysaccharide kinase (Kdo/WaaP) family
     0.0016   17.8   0.4     0.0037   16.6   0.0    1.7  2  Kinase-like     Kinase-like
     0.0071   15.4   0.0      0.011   14.8   0.0    1.2  1  Seadorna_VP7    Seadornavirus VP7
  ------ inclusion threshold ------
      0.033   13.0   0.0      0.058   12.2   0.0    1.3  1  Pkinase_fungal  Fungal protein kinase
      0.037   13.6   0.2        7.7    6.1   0.1    2.3  2  FTA2            Kinetochore Sim4 complex subunit FTA2


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  181.7   0.0   8.5e-57   1.7e-53       1     264 []     253     563 ..     253     563 .. 0.93

  Alignments for each domain:
  == domain 1  score: 181.7 bits;  conditional E-value: 8.5e-57
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHH.HHHHHHHHHHHHHS.CTTB--EEEEEEESSEEEEEEE--TTEBHHHHHHHHSS--H CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkke.kkvlrEikilkklk.hpnivrlyevfeekdelylvleyveggeladllerkgslse 97 
                 +++++ +G+G+fG+V  + +k++gki+A+K + k ++ kk++  +v++E  il+ +k  p +v+l  +f+++ +lyl++e+++gg+l+++l +  ++se
  EEA20344.1 253 FQTIKIIGKGAFGEVKLVQRKSDGKIYALKSLIKTEMFKKDQlAHVRAERDILADSKdNPWLVKLHASFQDSAYLYLLMEFLPGGDLMTMLIKYEIFSE 351
                 57899*******************************9999999**************9**********************************999**** PP

                 HHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCS........................................... CS
     Pkinase  98 eeakkiakqilegleylHskgiiHrDlKpeNiLidekgelKitDFGlakelesssk........................................... 153
                 + +++++++i+ ++e +H+ g++HrD+Kp+NiL+d+ g++K+tDFGl++  +++++                                           
  EEA20344.1 352 DITRFYMAEIVMAIEAVHKLGFLHRDIKPDNILLDRGGHIKLTDFGLSTGGKKTHDnayyqnllknstskdknrnsgffsdainltvsnrgqintwrks 450
                 *************************************************999999999***************************************** PP

                 ....BCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHHHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCTSHH...HHHTTS-HHHHHHHHHHT-SS CS
     Pkinase 154 ....ltsfvgtseYlAPEvlkeneyskkvDvWslGvilyelltgkppfsgekgkekvekeldqlekilkilgetkeklpeaseiseeakdllkkllkkd 248
                     + s vgt++Y+APE+ ++++y+  +D+Ws+G i++e l g ppf +e+++++++k+++           + + +p +  +s+e   l+++ l+ d
  EEA20344.1 451 rramAYSTVGTPDYIAPEIFNGQGYTYLCDWWSVGAIMFECLVGWPPFCAEDTTDTYRKIVNW---------RECLYFPDELVLSRESEGLIRSFLC-D 539
                 ***999*******************************************88888866666665.........3345678888889999999999998.5 PP

                 GCCSTT........HHHHHTSGGG CS
     Pkinase 249 pkkRlt........aeellqhpyl 264
                  ++R++        a+++++h ++
  EEA20344.1 540 AEHRIGneggqhggATQIKNHAFF 563
                 667888788888888888888776 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.0   0.1   9.3e-23   1.8e-19       3     158 ..     255     409 ..     253     421 .. 0.83
   2 !   15.8   0.0   3.3e-06    0.0066     162     218 ..     455     510 ..     435     525 .. 0.82

  Alignments for each domain:
  == domain 1  score: 70.0 bits;  conditional E-value: 9.3e-23
                  EEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS.-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHTCTTT CS
  Pkinase_Tyr   3 lgkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkkl.khpnivkllgvctkeepllivteyvkgGdLlkfLrkkekek 99 
                  + k +G+GafG+V   + k++ +   +k  +Kt  e  ++++ +++  e +i+ +  ++p +vkl++   ++  l++++e+++gGdL ++L k   e 
   EEA20344.1 255 TIKIIGKGAFGEVKLVQRKSDGKIYALKSLIKT--EMFKKDQLAHVRAERDILADSkDNPWLVKLHASFQDSAYLYLLMEFLPGGDLMTMLIKY--EI 348
                  6789**********9999944444444555554..4667777899999********9***********************************98..66 PP

                  SBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEETTEEEE-STTTHEET..TTSSE CS
  Pkinase_Tyr 100 ltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsenkvvkisDfGLardi..ekdde 158
                  ++ + +  +++++  ++e +++  ++Hrd+   N+Ll+++ ++k++DfGL+     ++d+ 
   EEA20344.1 349 FSEDITRFYMAEIVMAIEAVHKLGFLHRDIKPDNILLDRGGHIKLTDFGLSTGGkkTHDNA 409
                  66666666789***************************************98652133333 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 3.3e-06
                  TTSSTSGGGGS-HHHHHHSEEEHHHHHHHHHHHHHHHHTTSSGTTTTSHHHHHHHHH CS
  Pkinase_Tyr 162 keeaklpvkWmapEslkekkftsksDvWsfGvllwEiftlgespypglkneevlekl 218
                  + ++     ++apE+++ + +t   D Ws G +++E +  g  p+   +++++++k+
   EEA20344.1 455 AYSTVGTPDYIAPEIFNGQGYTYLCDWWSVGAIMFECLV-GWPPFCAEDTTDTYRKI 510
                  5556667789**************************998.99999998888888877 PP

>> Haspin_kinase  Haspin like kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   0.0   3.6e-09   7.1e-06     175     268 ..     309     414 ..     209     419 .. 0.72

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 3.6e-09
  Haspin_kinase 175 k.......pdfyseqqlflvlllkd.kGtdLeev..klkswkqalsifwqivkiLy.vaEtkfeFEHRdLhldniLvdknlnvtlidlklsRle.s 258
                    k            ++  +l+ll+++  G dL ++  k + +++    f+    +++ +a  k+ F HRd++ dniL+d+ +++ l d+ ls    +
     EEA20344.1 309 KdnpwlvkLHASFQDSAYLYLLMEFlPGGDLMTMliKYEIFSEDITRFYMAEIVMAiEAVHKLGFLHRDIKPDNILLDRGGHIKLTDFGLSTGGkK 404
                    35555555333445567777777763588888885677778877777886555554235579****************************987756 PP

  Haspin_kinase 259 segkvlytrl 268
                     +++++y +l
     EEA20344.1 405 THDNAYYQNL 414
                    6777777776 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.4     0.026        52      84     150 ..     122     201 ..      78     236 .. 0.65
   2 ?    3.9   0.0     0.022        43      41      88 ..     299     342 ..     279     368 .. 0.75
   3 !   14.8   0.1   1.1e-05     0.021     165     204 ..     370     407 ..     351     419 .. 0.81

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.026
                 S......HHHHHHHHHHHHHHHHHHCCHHCH..-S...TTTB-SHHCHTCCHHHHHHCHHHCCCGCCTCC...HHHHHHH CS
         APH  84 r......klsaaqlpellealgeflaalhqvd.pa...alpladflaqdlellrqlesatarllaselld...lleelee 150
                 r      + s+aq+p+ ++  g  + a h ++ +a   + p+  +++ +++++r+ e+ ++r++a++ l     +e +e+
  EEA20344.1 122 RpglsprAASPAQRPRTAGSTGPQQHAGHLAPgMAnrsSKPPGEEEELQRYPERYSENVHKRGKAAKELInvfFQENIER 201
                 34455566899********************9766776677778888999999999999886666555444553333333 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.022
                 HHHHHHHHHTT-B--B-CTTBS-EEETTEEEEEEE----EE-SSHHHH CS
         APH  41 vallrlLakagvpvPevlagdtddeeigllfalieyvpgrsllrklsa 88 
                  a+ + La+++   P ++ +  + +++ +l++l+e++pg +l +   +
  EEA20344.1 299 RAERDILADSKD-NPWLVKLHASFQDSAYLYLLMEFLPGGDLMT---M 342
                 444455555544.2333444459999**************9988...4 PP

  == domain 3  score: 14.8 bits;  conditional E-value: 1.1e-05
                 -EEEE-SS-SGGGEEEC..TTEEEEE---TT-EEEECCHH CS
         APH 165 ptvllHgDlhpgNllvdpddgrvtGviDfedaglgpplyD 204
                 + ++lH+D++p+N+l+d ++g++  + Df++++ g  ++D
  EEA20344.1 370 KLGFLHRDIKPDNILLD-RGGHI-KLTDFGLSTGGKKTHD 407
                 5789*************.77777.7889988876665555 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   3.3e-07   0.00066      95     167 ..     330     397 ..     322     426 .. 0.83

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 3.3e-07
         Kdo  95 lterlegaqdLedllakwaelaeelkrallkavgrliaklhragvnHadlyaknillqqeeeeeaeiwliDld 167
                 l+e l g  dL ++l k++ ++e  +r  + ++  +i+  h++g  H+d+ + nill+ ++    +i l D+ 
  EEA20344.1 330 LMEFLPG-GDLMTMLIKYEIFSEDITRFYMAEIVMAIEAVHKLGFLHRDIKPDNILLDRGG----HIKLTDFG 397
                 5555544.589999999888****************************************9....88888885 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   1.8e-06    0.0037     142     198 ..     351     405 ..     337     415 .. 0.85
   2 ?   -3.3   0.1       2.2   4.4e+03     227     242 ..     475     490 ..     470     504 .. 0.86

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 1.8e-06
  Kinase-like 142 etiarlllTlqlirlaanLqakglvhgkftvdnllldekgglmlggftaLvragtkv 198
                  e+i r ++ ++++  +   +++g +h ++++dn+lld+ g ++l++f+ L + g+k 
   EEA20344.1 351 EDITRFYM-AEIVMAIEAVHKLGFLHRDIKPDNILLDRGGHIKLTDFG-LSTGGKKT 405
                  67888888.889999999*****************************7.66666665 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 2.2
  Kinase-like 227 mthkldaWqlGlviyr 242
                  +t+  d W +G+ ++ 
   EEA20344.1 475 YTYLCDWWSVGAIMFE 490
                  89999******99885 PP

>> Seadorna_VP7  Seadornavirus VP7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   5.6e-06     0.011     144     209 ..     358     418 ..     348     443 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 5.6e-06
  Seadorna_VP7 144 vniivaglkdLmdfhsestnllhGDcnpenlmcDknGylklvDPvsLlertvvyvnieYesltqea 209
                   +  iv+   +++ +h  + + lh D++p+n++ D+ G +kl D +     + +  n +Y++l +++
    EEA20344.1 358 MAEIVM---AIEAVH--KLGFLHRDIKPDNILLDRGGHIKLTDFGLSTGGKKTHDNAYYQNLLKNS 418
                   556666...566777..7789**********************99999999999999999886655 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   2.9e-05     0.058     317     396 ..     363     480 ..     356     484 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2.9e-05
  Pkinase_fungal 317 kghrsLflkagiLHrDiSenNilit................................dskkegerkglLiD.LDlakelsddsses......... 369
                      + +  + k g+LHrDi  +Nil+                                  sk++++++g+ +D ++l ++       +         
      EEA20344.1 363 MAIEAVH-KLGFLHRDIKPDNILLDrgghikltdfglstggkkthdnayyqnllknsTSKDKNRNSGFFSDaINLTVSNR----GQintwrksrr 452
                     5556667.899**************9999999999999999999999999999987655666888888887423332222....11112222222 PP

  Pkinase_fungal 370 .garertGTleFmaievlkgeeHsyrhD 396
                       a   +GT+ ++a e+ +g+  +y+ D
      EEA20344.1 453 aMAYSTVGTPDYIAPEIFNGQGYTYLCD 480
                     2557799999999999999888888776 PP

>> FTA2  Kinetochore Sim4 complex subunit FTA2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.1    0.0039       7.7      21      60 ..     248     291 ..     231     323 .. 0.74
   2 ?    5.3   0.0    0.0065        13     176     204 ..     356     384 ..     345     400 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0039
        FTA2  21 e..kdiefleyLgkglhsiV..lkvkirgkeYALKlFrfleaee 60 
                 e   +++ ++++gkg+ + V  ++ k +gk+YALK  ++ e+ +
  EEA20344.1 248 EspSNFQTIKIIGKGAFGEVklVQRKSDGKIYALKSLIKTEMFK 291
                 33589999******9999661166678899*****877774433 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0065
        FTA2 176 sqlpkllrdlkklhklgIvvrDlkeenyi 204
                  ++ +++  ++ +hklg ++rD+k++n++
  EEA20344.1 356 FYMAEIVMAIEAVHKLGFLHRDIKPDNIL 384
                 578899999******************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (638 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       641  (0.0357521); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.71u 0.33s 00:00:01.04 Elapsed: 00:00:00.52
# Mc/sec: 3696.55
//
Query:       EEA20345.1  [L=408]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.2e-06   28.6  12.3    2.2e-06   27.7  12.3    1.4  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
      3e-06   26.3   0.9    4.3e-06   25.8   0.9    1.2  1  Fungal_trans_2  Fungal specific transcription factor domain
  ------ inclusion threshold ------
      0.084   12.6   0.1        1.2    8.9   0.0    2.5  2  RRM             Putative RRM domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.7  12.3   3.6e-10   2.2e-06       2      34 ..       9      43 ..       8      48 .. 0.87

  Alignments for each domain:
  == domain 1  score: 27.7 bits;  conditional E-value: 3.6e-10
                S-HHHHHCT---STSSSS..-HHHHHCTHHHCCCC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPa..CsnCkklnleCtfys 34
                +Cd Crk+K KCda kP   C +C +l  +Ct y 
  EEA20345.1  9 GCDACRKQKKKCDAPKPPtkCPRCTRLKIPCTGYG 43
                7*************666669************885 PP

>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   0.9   7.1e-10   4.3e-06       3     107 ..     104     202 ..     102     228 .. 0.89

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 7.1e-10
  Fungal_trans_2   3 ldyyldnvapllspvpessnpfrkvllplalsnkallhallalsafhlqskgpkdslereakrykslalkelqealaelsstlsrnekykdiLaa 97 
                     ++ +l+++a  ++ vp  +++  ++l + al+n +l++++lal+a+ ++++g+k +  r a+ y+ +a+ e++  l+ + +++      +d+  +
      EEA20345.1 104 MHRWLTRTAWCFYMVPKDKAYLETLLPQAALMNSSLMNSILALAAADFAHSGQKAY-LRPALEYHAKAVAEMRIQLTSVGQRSI-----DDLYPS 192
                     5666667777778888889999999999************************9998.899999999***999999999999999.....****** PP

  Fungal_trans_2  98 iLllcsieis 107
                      Ll+  +  +
      EEA20345.1 193 ALLMAAFNFV 202
                     *999988754 PP

>> RRM  Putative RRM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.0    0.0002       1.2       8      30 ..     119     141 ..     117     158 .. 0.84
   2 ?    0.5   0.0     0.083   4.9e+02      17      33 ..     189     206 ..     187     211 .. 0.74

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0002
         RRM   8 PFDlaYgasLLPShLLvgSPFis 30 
                 P D aY  +LLP   L++S  ++
  EEA20345.1 119 PKDKAYLETLLPQAALMNSSLMN 141
                 6699***************6665 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.083
         RRM  17 LLPShLLvgS.PFissPn 33 
                 L PS LL+    F+ sP+
  EEA20345.1 189 LYPSALLMAAfNFVASPQ 206
                 67******8634667774 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (408 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       653  (0.0364214); expected 358.6 (0.02)
Passed bias filter:                      498  (0.0277762); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.24s 00:00:00.77 Elapsed: 00:00:00.41
# Mc/sec: 2970.21
//
Query:       EEA20346.1  [L=513]
Description: TIM complex componenet Tim54 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   4.5e-151  502.9   0.6   5.3e-151  502.6   0.6    1.1  1  Tim54          Inner membrane protein import complex subunit 


Domain annotation for each model (and alignments):
>> Tim54  Inner membrane protein import complex subunit Tim54
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  502.6   0.6    3e-155  5.3e-151       1     374 []      29     450 ..      29     450 .. 0.94

  Alignments for each domain:
  == domain 1  score: 502.6 bits;  conditional E-value: 3e-155
       Tim54   1 npalkmlGlpnlrlkLPSrnWliFltvlgsitaaiiYDkrekkriqkkwaelvehlakepleveelpRkltvflaaPPgDgLrsarkhfkeYvKpiLva 99 
                 np++km+G+pn+rl+LPSrnW+iFlt++g +taai+YD+r+kkr+q+kwa+lv+h++ke+l++e+ +Rkltvfl+aPPgDgLrsar++f eYvKp+Lv+
  EEA20346.1  29 NPVFKMMGIPNFRLRLPSRNWMIFLTITGGFTAAITYDRRQKKRAQQKWADLVAHISKETLPIEQNRRKLTVFLSAPPGDGLRSAREYFIEYVKPVLVS 127
                 9************************************************************************************************** PP

       Tim54 100 aalDyevvegrrqGdiRaevAeriRklRrkaeeeekeeeeekeeeelkkleelrkklgieeeegagGviviGRhayKEYirGlhEGlLGPldkpeepee 198
                 aalDyev+egr++G+iRa +Ae+iR++Rr+a+e++ +  +e+++e++  ++e+r+++g+++e+g+ G+iviGRh++KEYirGlhEG+LGPld+p+ pe+
  EEA20346.1 128 AALDYEVIEGRKEGEIRAGTAEKIREYRRQAGEQS-SVVQEPSKESI--IAETRRRMGVTDEPGPLGDIVIGRHTWKEYIRGLHEGWLGPLDPPPPPEV 223
                 *******************************9995.58899999999..9********************************************99999 PP

       Tim54 199 eeaeeeeeeeeeekeeeeeeeeeeeeekeeekeeekeeee.eeeekekkkkvpkp.yispedYasaelppeiPellqpvlviplphllGflntpiriyr 295
                  ++++++ +  +  ++++++e++e+ +++++++ e++  e e+e++++k+k p+p yis+ dY+s++lp++iP +++++l++p+phllGflntpiriyr
  EEA20346.1 224 PTEATSSVDVPDVPRDTATAESTENPDSSSTSTPEEKLAEpEKEKEKEKPKGPTPaYISTVDYSSRNLPATIPVSFEASLPVPFPHLLGFLNTPIRIYR 322
                 99888888888887777777766666666555555544440444455599999999******************************************* PP

       Tim54 296 fltrRkladevgrevaavvlak.irpyeek......................sekaeqqellkeeEkdWpksvvkkekee................... 352
                 +lt+R+lad+vg++vaa+vla+ +rpy e                       ++ +eqq+ll++eEk+W+ksv+k ++++                   
  EEA20346.1 323 YLTKRYLADAVGEQVAAAVLASaSRPYYEGltnssesdlgpstepftpetqsQQIYEQQTLLDHEEKEWHKSVRKAAEARkqqaeadnsasvsddtqpv 421
                 **********************9****************************9999********************99998899**************** PP

       Tim54 353 .......kesewvqelvlDeriasrmrrf 374
                        +e+ew++++v+D+ria+rm+r+
  EEA20346.1 422 aqpdilkEEREWIDDVVIDPRIAARMSRY 450
                 ******99******************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (513 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1209  (0.0674327); expected 358.6 (0.02)
Passed bias filter:                      646  (0.036031); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.44
# Mc/sec: 3508.99
//
Query:       EEA20347.1  [L=838]
Description: acetyltransferase catalytic subunit (NAT1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   3.5e-222  738.9  23.1   2.9e-219  729.3  18.6    2.3  2  NARP1            NMDA receptor-regulated protein 1
    2.6e-20   72.7  31.4    0.00078   19.9   0.3    7.3  6  TPR_19           Tetratricopeptide repeat
    3.1e-17   61.8  22.6       0.12   13.2   0.2   11.1 10  TPR_14           Tetratricopeptide repeat
    6.2e-17   60.3  41.6     0.0012   18.8   0.2   11.5 11  TPR_2            Tetratricopeptide repeat
    7.5e-13   48.9  22.7      0.077   13.7   0.6    8.7  8  TPR_16           Tetratricopeptide repeat
    5.2e-12   45.8  14.1    1.2e-05   25.5   0.7    5.2  5  ANAPC3           Anaphase-promoting complex, cyclosome, subun
    3.4e-09   36.7  10.3      0.034   14.3   1.6    6.4  6  TPR_9            Tetratricopeptide repeat
    1.3e-07   31.5   8.3       0.61   10.6   0.0    6.6  6  TPR_17           Tetratricopeptide repeat
    2.6e-07   30.2  12.3    0.00026   20.6   0.2    6.4  7  TPR_11           TPR repeat
    1.4e-06   28.0  30.6     0.0008   19.4   0.0    8.5  8  TPR_8            Tetratricopeptide repeat
    2.2e-06   27.3  36.6    3.9e-05   23.3   0.5   10.0 10  TPR_1            Tetratricopeptide repeat
    0.00018   21.7  30.4        1.1    9.5   0.3    8.7  8  TPR_12           Tetratricopeptide repeat
    0.00021   20.8   2.9        2.4    7.4   0.0    3.9  3  TPR_MalT         MalT-like TPR region
      0.001   19.5   4.7        1.9    9.3   0.0    5.2  5  TPR_4            Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.012   15.6   3.8        2.2    8.4   0.1    3.7  3  TPR_3            Tetratricopeptide repeat
       0.28   11.9  24.7        2.3    9.0   0.2    8.6  9  TPR_6            Tetratricopeptide repeat
       0.69   10.0   9.3       0.95    9.6   0.1    4.2  3  Fis1_TPR_C       Fis1 C-terminal tetratricopeptide repeat
        3.2    7.5   7.1        3.4    7.4   2.0    2.5  2  Phage_Nu1        Phage DNA packaging protein Nu1
        6.7    6.3   7.3        0.8    9.3   0.2    2.9  4  DUF2229          CoA enzyme activase uncharacterised domain (


Domain annotation for each model (and alignments):
>> NARP1  NMDA receptor-regulated protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.6   0.1   9.7e-05     0.092     201     258 ..      19      75 ..      12      79 .. 0.91
   2 !  729.3  18.6  3.1e-222  2.9e-219       1     515 []     184     697 ..     184     697 .. 0.97

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 9.7e-05
                 HHHHHT-SHHHHHHHHHHHHH-TT-HHHHHHHHHHHHHTT-HHHHHHHHHHHHHCTTT CS
       NARP1 201 hydklgsrekAleyidkaiehtptlvelyltKarilkhaGdlkkAaevmeearklDla 258
                 hy++ ++++k +++ d+ ++++p+  + + +Ka i+   G+l++A  ++++a k D +
  EEA20347.1  19 HYEN-KQYKKGIKTADQILRKNPNHGDTQAMKALIMSNLGQLEEAFVLAKTALKNDMK 75 
                 6754.7899****************************************999988865 PP

  == domain 2  score: 729.3 bits;  conditional E-value: 3.1e-222
                 HHHHHHHHHHHHHHHHHTHHHHHHHHHHHHGGG---HHHHHHHHHHHHHHTT-HHHHHHHHHHHHHH-TT-CHHHHHHHHHT..SSS-HHHHHHHHHHT CS
       NARP1   1 leesellLyknqiieeagkleeAlehLeekekqivDklavketkaelllkLgrkeeAeatyeaLlernpenskYyeglekakklskedeeallalydel 99 
                 +e+se++Lykn+ii+e+g+le+AlehL+++ k++ D+lav+e+ka++ll+L+rk+eAea+y aLl+rnpens+Yy+gl+kak+l+++d++al+a+ydel
  EEA20347.1 184 MEHSEAVLYKNTIIAESGDLERALEHLDTAGKRCSDVLAVMEMKADYLLRLDRKAEAEAAYAALLDRNPENSHYYDGLIKAKGLAESDHQALKAVYDEL 282
                 79************************************************************************************************* PP

                 TTS-TT-SHHHHTHHHH--HHHHHHHHHHHHHHHHHCT-TTHHHHHGGGGGGSCHHHHHHHHHHHHHT...TTTTSSSSTTGG.GSS----SSHHHHHH CS
       NARP1 100 aekyprsdaprRlpLdfleGeeFkelvdkYlrkaLrkgvPslfanlksLYedkeKvkileelvegyvk...slktsgklsesdnedsekepesallwvl 195
                 +ek+pr+daprR+pLdfleG++Fk+++d+Yl+++LrkgvPslfan+k LY+ ++K++ ++elvegy++   + +t+g+ ++++ ed ++ +e++   + 
  EEA20347.1 283 VEKFPRGDAPRRIPLDFLEGDDFKKAADSYLQRMLRKGVPSLFANIKVLYDRPAKRDAVQELVEGYAAgkvQPQTNGSSESQKPED-KTMFEAS---TF 377
                 *******************************************************************9765667777777666444.7777777...9* PP

                 HHHHHHHHHHT-SH..HHHHHHHHHHHH-TT-HHHHHHHHHHHHHTT-HHHHHHHHHHHHHCTTT-HHHHHHHHHHHHHTT-HHHHHHHHTTTS-TTS. CS
       NARP1 196 yflAqhydklgsre..kAleyidkaiehtptlvelyltKarilkhaGdlkkAaevmeearklDlaDRyiNskcakymLradeveeAeetvslFtreev. 291
                 yflAqhy+++ sr+  kA++y++kai+  p++v++++tKari+kh+Gdl kAaevmeearklD++DRyiN+k+aky Lr+de+e+  e +s+Ftr+e+ 
  EEA20347.1 378 YFLAQHYNYYLSRDlqKAMDYVEKAISLVPKSVDYHMTKARIYKHYGDLPKAAEVMEEARKLDEKDRYINTKAAKYRLRNDENEKGLEDMSKFTRNETv 476
                 *********9998888*********************************************************************************** PP

                 .HHHHHHHHTT-HHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHHHHCTTTHHHHHHHHT-HHHHHHHHHHHCTTT-SHHHHHHHHHHHHHHHHHHH- CS
       NARP1 292 .daledlnemqcmWfetedgeaylrqkklglALKrfhavekhFdeieeDqFDFHtyclRkmtlraYvdllrledelrshpfyvkaakgaievYlkledk 389
                  +al+dl+emqc+W++tedge+ylrqkklglALKrfhav+++Fd+++eDqFDFH+++lRk+++raYvd++r+ed+lr+hpfy+++a +ai++Y+ l+d+
  EEA20347.1 477 gGALGDLHEMQCVWYLTEDGESYLRQKKLGLALKRFHAVYNIFDVWQEDQFDFHSFSLRKGMIRAYVDMVRWEDHLRDHPFYTRMALSAIKAYVLLHDQ 575
                 *************************************************************************************************** PP

                 TTGGG---HHHHHT-S-HHHHHHHHHHHHHHHHHHHHHHHHHHHHH--.......-------------S-SSSTTTT-S-HHHHHHHHHTTTGGGTTT- CS
       NARP1 390 pkakeeekeeaksaelseaerkklrkkakkaekkaekeeaekaekekekkaaekkakkedeeakkededplgekLvkteepLeeAlkflkpLlklaaen 488
                 p++ ++++  a+++ ++e+erkk+ kkakk+++++ek+ea+k+e +k+   ++++ak++d+e kked+dp+g+kLv+t+epL++A+kfl+pLl+l+a +
  EEA20347.1 576 PDLVHGPTF-ADMNGMDEEERKKAIKKAKKEQQRLEKAEADKQELKKA---SAANAKGADGEVKKEDTDPFGNKLVQTTEPLKDAMKFLTPLLELSAGD 670
                 ********9.56677**************************7776655...67889******************************************* PP

                 THHHHHHHHHHHHTT-HHHHHHHHHHH CS
       NARP1 489 iethllafevyiRkkklllalkalkka 515
                 i +++++fevyiR++k++lalk+l +a
  EEA20347.1 671 IRAQTAGFEVYIRRQKYALALKCLLAA 697
                 ************************987 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.1   0.0   5.2e-05     0.049       2      55 ..      20      73 ..      19      78 .. 0.90
   2 !   17.0   0.4   6.8e-06    0.0064       3      41 ..      89     127 ..      87     128 .. 0.95
   3 !   14.2   0.0     5e-05     0.047      17      54 ..     137     174 ..     134     181 .. 0.86
   4 !   16.9   2.9     7e-06    0.0066       3      62 ..     199     258 ..     198     265 .. 0.86
   5 !   19.9   0.3   8.3e-07   0.00078       4      67 ..     389     452 ..     386     453 .. 0.93
   6 !    7.7   0.3    0.0053         5       8      61 ..     654     707 ..     653     712 .. 0.91

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 5.2e-05
      TPR_19  2 laegdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeed 55
                +++++y   ++   q+l ++p++++ ++  A ++ +lgql+eA  l +++++ d
  EEA20347.1 20 YENKQYKKGIKTADQILRKNPNHGDTQAMKALIMSNLGQLEEAFVLAKTALKND 73
                5789999************************************88888888776 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 6.8e-06
      TPR_19   3 aegdyaeAlalleqalqedpknaearllLAeallalgql 41 
                 ae++y+eA+++++ al  +p+++ ++ +LA +++++ ++
  EEA20347.1  89 AEKNYEEAIKAYRFALRLEPESQPIQRDLALLQIQMRDY 127
                 899********************************9886 PP

  == domain 3  score: 14.2 bits;  conditional E-value: 5e-05
      TPR_19  17 alqedpknaearllLAeallalgqldeAealLdalpee 54 
                 +lq+ p     + +LA+a+  +g+l+eAe++L+++ e 
  EEA20347.1 137 MLQARPSFRQNWTALAIAYHLAGNLTEAENVLNTYEET 174
                 67888888888899*******************99876 PP

  == domain 4  score: 16.9 bits;  conditional E-value: 7e-06
      TPR_19   3 aegdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpddarya 62 
                 ++gd+++Al++l  a +   + +++    A+ ll l + +eAea+ +al++ +p ++ y 
  EEA20347.1 199 ESGDLERALEHLDTAGKRCSDVLAVMEMKADYLLRLDRKAEAEAAYAALLDRNPENSHYY 258
                 78*************88888777777777**************************96654 PP

  == domain 5  score: 19.9 bits;  conditional E-value: 8.3e-07
      TPR_19   4 egdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpddaryasLlAk 67 
                 + d++ A+++ e+a++  pk+ +  +  A+++   g+l +A ++++++ + d +d ++ +  Ak
  EEA20347.1 389 SRDLQKAMDYVEKAISLVPKSVDYHMTKARIYKHYGDLPKAAEVMEEARKLDEKDRYINTKAAK 452
                 579***************************************************8887776665 PP

  == domain 6  score: 7.7 bits;  conditional E-value: 0.0053
      TPR_19   8 aeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpddary 61 
                  +A+++l+ +l+ ++++ +a+ +  e+++    ++ A ++L a+ + d  d+ +
  EEA20347.1 654 KDAMKFLTPLLELSAGDIRAQTAGFEVYIRRQKYALALKCLLAAHAIDSLDPTL 707
                 69***************************************9998888777765 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.047        44      11      42 ..      19      50 ..      12      52 .. 0.87
   2 ?    7.2   0.0     0.011        10       4      39 ..      46      81 ..      43      86 .. 0.86
   3 !   13.2   0.2   0.00013      0.12       8      42 ..      84     118 ..      77     120 .. 0.90
   4 !    9.6   0.0    0.0019       1.8       4      30 ..     148     174 ..     145     183 .. 0.87
   5 ?    2.9   0.0      0.26   2.5e+02      13      42 ..     199     228 ..     197     229 .. 0.84
   6 !   10.1   1.6    0.0013       1.2       7      38 ..     227     258 ..     222     264 .. 0.86
   7 ?   -1.9   0.0       9.5     9e+03      16      33 ..     271     288 ..     267     292 .. 0.80
   8 !    8.2   0.0    0.0053         5      11      43 ..     386     418 ..     375     419 .. 0.81
   9 ?    7.1   0.0     0.012        12       6      42 ..     415     451 ..     410     453 .. 0.86
  10 !    7.9   0.2    0.0068       6.4       8      43 ..     678     713 ..     670     714 .. 0.91

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.047
      TPR_14 11 llalGdpdeAiallrralalaPddaeawllla 42
                ++++ ++++ i+ ++++l+++P++ +++ + a
  EEA20347.1 19 HYENKQYKKGIKTADQILRKNPNHGDTQAMKA 50
                67789******************998888876 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.011
      TPR_14  4 llalaeallalGdpdeAiallrralalaPddaeawl 39
                +++ a ++ +lG+++eA  l++ al+ + ++ + w 
  EEA20347.1 46 QAMKALIMSNLGQLEEAFVLAKTALKNDMKSHVCWH 81
                567789999*****************9999888775 PP

  == domain 3  score: 13.2 bits;  conditional E-value: 0.00013
      TPR_14   8 aeallalGdpdeAiallrralalaPddaeawllla 42 
                 + +++a  +++eAi+++r al+l P+++ +++ la
  EEA20347.1  84 GLLYRAEKNYEEAIKAYRFALRLEPESQPIQRDLA 118
                 5689999*********************9999998 PP

  == domain 4  score: 9.6 bits;  conditional E-value: 0.0019
      TPR_14   4 llalaeallalGdpdeAiallrralal 30 
                 + ala a+  +G++ eA+++l+ + ++
  EEA20347.1 148 WTALAIAYHLAGNLTEAENVLNTYEET 174
                 889******************998876 PP

  == domain 5  score: 2.9 bits;  conditional E-value: 0.26
      TPR_14  13 alGdpdeAiallrralalaPddaeawllla 42 
                 ++Gd+++A+++l+ a +++ d +++  + a
  EEA20347.1 199 ESGDLERALEHLDTAGKRCSDVLAVMEMKA 228
                 68************9999988888777766 PP

  == domain 6  score: 10.1 bits;  conditional E-value: 0.0013
      TPR_14   7 laeallalGdpdeAiallrralalaPddaeaw 38 
                  a++ll+l++ +eA+a++ ++l+++P++  ++
  EEA20347.1 227 KADYLLRLDRKAEAEAAYAALLDRNPENSHYY 258
                 4899**********************997655 PP

  == domain 7  score: -1.9 bits;  conditional E-value: 9.5
      TPR_14  16 dpdeAiallrralalaPd 33 
                 d+++  a+++++++++P 
  EEA20347.1 271 DHQALKAVYDELVEKFPR 288
                 77788899******9994 PP

  == domain 8  score: 8.2 bits;  conditional E-value: 0.0053
      TPR_14  11 llalGdpdeAiallrralalaPddaeawlllaq 43 
                 ++ ++d+++A+++ ++a++l P++ ++++  a+
  EEA20347.1 386 YYLSRDLQKAMDYVEKAISLVPKSVDYHMTKAR 418
                 35689*******************999988776 PP

  == domain 9  score: 7.1 bits;  conditional E-value: 0.012
      TPR_14   6 alaeallalGdpdeAiallrralalaPddaeawllla 42 
                   a+++ + Gd+ +A+++ ++a +l+ +d+ +++  a
  EEA20347.1 415 TKARIYKHYGDLPKAAEVMEEARKLDEKDRYINTKAA 451
                 5699***********************9988776665 PP

  == domain 10  score: 7.9 bits;  conditional E-value: 0.0068
      TPR_14   8 aeallalGdpdeAiallrralalaPddaeawlllaq 43 
                  e++ ++++++ A+++l +a a +  d++++++l++
  EEA20347.1 678 FEVYIRRQKYALALKCLLAAHAIDSLDPTLHIQLVR 713
                 589*****************************9987 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.0     0.012        11      11      34 .]      19      42 ..      17      42 .. 0.95
   2 ?    4.2   0.0     0.059        56       7      31 ..      49      73 ..      44      76 .. 0.87
   3 !   18.8   0.2   1.2e-06    0.0012       4      33 ..      80     109 ..      78     110 .. 0.91
   4 ?    5.5   0.0     0.022        21       4      24 ..     148     168 ..     146     170 .. 0.89
   5 ?    3.0   0.0      0.14   1.4e+02      13      27 ..     199     213 ..     197     219 .. 0.86
   6 !   10.7   1.4    0.0005      0.47       6      34 .]     226     254 ..     222     254 .. 0.92
   7 !   11.6   0.0   0.00025      0.24      10      33 ..     385     408 ..     384     409 .. 0.93
   8 !   14.6   0.1   2.8e-05     0.026       2      34 .]     411     443 ..     410     443 .. 0.93
   9 ?    0.4   0.1         1   9.6e+02       8      27 ..     496     515 ..     496     519 .. 0.85
  10 !    6.9   0.4    0.0082       7.7      10      31 ..     680     701 ..     679     704 .. 0.92
  11 ?   -2.7   0.6       9.9   9.4e+03       9      27 ..     814     832 ..     811     834 .. 0.66

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.012
       TPR_2 11 yyklgdyeeAleafekAleldPnn 34
                +y++++y++ ++  ++ l+ +Pn+
  EEA20347.1 19 HYENKQYKKGIKTADQILRKNPNH 42
                89********************97 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.059
       TPR_2  7 lGlayyklgdyeeAleafekAleld 31
                 +l+  +lg++eeA  + + Al+ d
  EEA20347.1 49 KALIMSNLGQLEEAFVLAKTALKND 73
                6889999**************9976 PP

  == domain 3  score: 18.8 bits;  conditional E-value: 1.2e-06
       TPR_2   4 lynlGlayyklgdyeeAleafekAleldPn 33 
                 ++  Gl+y++ ++yeeA++a++ Al+l+P+
  EEA20347.1  80 WHVFGLLYRAEKNYEEAIKAYRFALRLEPE 109
                 666699**********************97 PP

  == domain 4  score: 5.5 bits;  conditional E-value: 0.022
       TPR_2   4 lynlGlayyklgdyeeAleaf 24 
                 + +l+ ay  +g++ eA++ +
  EEA20347.1 148 WTALAIAYHLAGNLTEAENVL 168
                 889**************9866 PP

  == domain 5  score: 3.0 bits;  conditional E-value: 0.14
       TPR_2  13 klgdyeeAleafekA 27 
                 ++gd+e+Ale+++ A
  EEA20347.1 199 ESGDLERALEHLDTA 213
                 68**********998 PP

  == domain 6  score: 10.7 bits;  conditional E-value: 0.0005
       TPR_2   6 nlGlayyklgdyeeAleafekAleldPnn 34 
                 + ++ +++l++ +eA++a+ + l  +P+n
  EEA20347.1 226 MKADYLLRLDRKAEAEAAYAALLDRNPEN 254
                 57899**********************97 PP

  == domain 7  score: 11.6 bits;  conditional E-value: 0.00025
       TPR_2  10 ayyklgdyeeAleafekAleldPn 33 
                  yy + d+++A ++ ekA++l P+
  EEA20347.1 385 NYYLSRDLQKAMDYVEKAISLVPK 408
                 69*******************997 PP

  == domain 8  score: 14.6 bits;  conditional E-value: 2.8e-05
       TPR_2   2 ealynlGlayyklgdyeeAleafekAleldPnn 34 
                 ++++  +++y + gd+ +A+e +e+A +ld+++
  EEA20347.1 411 DYHMTKARIYKHYGDLPKAAEVMEEARKLDEKD 443
                 68999*************************875 PP

  == domain 9  score: 0.4 bits;  conditional E-value: 1
       TPR_2   8 GlayyklgdyeeAleafekA 27 
                 G++y++++++  Al+ f ++
  EEA20347.1 496 GESYLRQKKLGLALKRFHAV 515
                 889**********9988765 PP

  == domain 10  score: 6.9 bits;  conditional E-value: 0.0082
       TPR_2  10 ayyklgdyeeAleafekAleld 31 
                 +y+++++y+ Al+++ +A ++d
  EEA20347.1 680 VYIRRQKYALALKCLLAAHAID 701
                 79****************9998 PP

  == domain 11  score: -2.7 bits;  conditional E-value: 9.9
       TPR_2   9 layyklgdyeeAleafekA 27 
                 +a+ k+   e+A++ +++A
  EEA20347.1 814 DAATKQAYNEKAHNKWKEA 832
                 5555555667888887777 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.0    0.0015       1.5       6      66 ..      18      75 ..      13      77 .. 0.92
   2 !   13.7   0.6   8.2e-05     0.077       4      42 ..      84     119 ..      82     129 .. 0.81
   3 ?    3.2   0.2      0.15   1.4e+02       3      58 ..     117     169 ..     115     175 .. 0.78
   4 ?    3.8   0.1     0.097        92      10      60 ..     158     213 ..     149     219 .. 0.73
   5 !   11.2   3.5   0.00049      0.46       2      34 ..     226     255 ..     225     261 .. 0.86
   6 !   12.6   0.1   0.00018      0.17      10      64 ..     389     440 ..     380     443 .. 0.90
   7 ?    0.7   0.0       0.9   8.5e+02       4      23 ..     496     515 ..     495     517 .. 0.88
   8 ?    0.7   0.0      0.92   8.7e+02       6      27 ..     680     701 ..     677     722 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0015
      TPR_16  6 aalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraalraapd 66
                 ++++++y + ++ +++ l+++   P + + +  ++++   +g l+eA  l + al+++++
  EEA20347.1 18 RHYENKQYKKGIKTADQILRKN---PNHGDTQAMKALIMSNLGQLEEAFVLAKTALKNDMK 75
                5899******************...************************999999999875 PP

  == domain 2  score: 13.7 bits;  conditional E-value: 8.2e-05
      TPR_16   4 araalragdyddAaaaleaalkrdpssPdaaeAllllgd 42 
                 ++++++ ++y++A++a++ al++    P+    +  l++
  EEA20347.1  84 GLLYRAEKNYEEAIKAYRFALRLE---PESQPIQRDLAL 119
                 678999999***************...887766666666 PP

  == domain 3  score: 3.2 bits;  conditional E-value: 0.15
      TPR_16   3 laraalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyr 58 
                 la++ ++ +dy+  +   ++ l ++   P  ++ + +l+ a+  +g+l+eA+ +++
  EEA20347.1 117 LALLQIQMRDYPGYIQSRNTMLQAR---PSFRQNWTALAIAYHLAGNLTEAENVLN 169
                 6777777777777777777778888...88888899999***********995555 PP

  == domain 4  score: 3.8 bits;  conditional E-value: 0.097
      TPR_16  10 agdyddAaaaleaalkrdpssPd.....aaeAllllgdaalrqgrlaeAaalyraa 60 
                 ag+ ++A+++l+++ +  + +P      + eA l+++ + ++ g+l++A++ ++ a
  EEA20347.1 158 AGNLTEAENVLNTYEETLKTPPPrtdmeHSEAVLYKNTIIAESGDLERALEHLDTA 213
                 67777777776665555555554588889999999999999999999999877765 PP

  == domain 5  score: 11.2 bits;  conditional E-value: 0.00049
      TPR_16   2 alaraalragdyddAaaaleaalkrdpssPdaa 34 
                 ++a+++lr+ + ++A+aa+ a+l+r+   P++ 
  EEA20347.1 226 MKADYLLRLDRKAEAEAAYAALLDRN---PENS 255
                 689***********************...6643 PP

  == domain 6  score: 12.6 bits;  conditional E-value: 0.00018
      TPR_16  10 agdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraalraa 64 
                 ++d ++A  + e a+ +    P  ++ ++ +++++ + g+l++Aa++ ++a + +
  EEA20347.1 389 SRDLQKAMDYVEKAISLV---PKSVDYHMTKARIYKHYGDLPKAAEVMEEARKLD 440
                 7899**************...*****************************98765 PP

  == domain 7  score: 0.7 bits;  conditional E-value: 0.9
      TPR_16   4 araalragdyddAaaaleaa 23 
                 + ++lr+++   A+++++a+
  EEA20347.1 496 GESYLRQKKLGLALKRFHAV 515
                 56899**********99986 PP

  == domain 8  score: 0.7 bits;  conditional E-value: 0.92
      TPR_16   6 aalragdyddAaaaleaalkrd 27 
                  ++r+++y+ A++ l aa + d
  EEA20347.1 680 VYIRRQKYALALKCLLAAHAID 701
                 58999********998886655 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.5   0.7   1.2e-08   1.2e-05       1      79 [.      21     100 ..      21     103 .. 0.92
   2 ?    0.3   0.0      0.89   8.4e+02      19      49 ..     141     171 ..     135     179 .. 0.73
   3 !   12.4   0.3   0.00015      0.14      11      79 ..     170     244 ..     161     247 .. 0.81
   4 !   12.4   0.1   0.00015      0.14      27      81 ..     378     435 ..     349     436 .. 0.82
   5 ?    0.8   0.0      0.61   5.7e+02       4      49 ..     652     697 ..     649     723 .. 0.82

  Alignments for each domain:
  == domain 1  score: 25.5 bits;  conditional E-value: 1.2e-08
                 HTT-HHHHHHHHHHHH.HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHHH CS
      ANAPC3   1 dqnnyknAiflaerllaaetespedayllAlclylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaaL 79 
                 ++++yk+ i  a+ +l +++++ +   ++Al + ++gq ++A+ l+++a k + ks+ c+ +f+  + + k+yeeAi+a+
  EEA20347.1  21 ENKQYKKGIKTADQILRKNPNHGDTQAMKALIMSNLGQLEEAFVLAKTAlKNDMKSHVCWHVFGLLYRAEKNYEEAIKAY 100
                 689*************6666666667779************************************************997 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.89
                 HH--HHHHHHHHHHHHHTT-HHHHHHHHHCT CS
      ANAPC3  19 etespedayllAlclylngqykrAyellrka 49 
                  +   ++  +lA ++ l+g+ ++A ++l+++
  EEA20347.1 141 RPSFRQNWTALAIAYHLAGNLTEAENVLNTY 171
                 5555666677888999999999999999887 PP

  == domain 3  score: 12.4 bits;  conditional E-value: 0.00015
                 HHHHHH......HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHHH CS
      ANAPC3  11 laerlla.....aetespedayllAlclylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaaL 79 
                  +e  l+     ++ e++e+++++     ++g+ +rA+e l++a k  s  l++   +A  ll L++  eA+aa+
  EEA20347.1 170 TYEETLKtppprTDMEHSEAVLYKNTIIAESGDLERALEHLDTAgKRCSDVLAVMEMKADYLLRLDRKAEAEAAY 244
                 555555333344778899999999********************66666667********************997 PP

  == domain 4  score: 12.4 bits;  conditional E-value: 0.00015
                 HHHHH..HHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHHH-S CS
      ANAPC3  27 yllAl..clylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaaLek 81 
                 y+lA+   +yl+ + ++A+++++ka  l +ks  +++++A+ +  ++ + +A  ++e+
  EEA20347.1 378 YFLAQhyNYYLSRDLQKAMDYVEKAiSLVPKSVDYHMTKARIYKHYGDLPKAAEVMEE 435
                 445541158*********************************9999999999888776 PP

  == domain 5  score: 0.8 bits;  conditional E-value: 0.61
                 -HHHHHHHHHHHH.HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCT CS
      ANAPC3   4 nyknAiflaerllaaetespedayllAlclylngqykrAyellrka 49 
                  +k+A+ ++ +ll+ ++ +  +  +  +++ ++++y  A++ l  a
  EEA20347.1 652 PLKDAMKFLTPLLELSAGDIRAQTAGFEVYIRRQKYALALKCLLAA 697
                 57889999999999999999999999999********999998877 PP

>> TPR_9  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0     0.085        80       4      48 ..      18      62 ..      17      64 .. 0.92
   2 !   14.3   1.6   3.6e-05     0.034       4      60 ..      86     142 ..      84     158 .. 0.85
   3 ?   -0.3   0.0       1.3   1.2e+03      21      55 ..     137     171 ..     134     183 .. 0.84
   4 ?   -0.0   0.0       1.1   9.9e+02      40      58 ..     198     216 ..     195     228 .. 0.64
   5 !   14.2   0.0   3.7e-05     0.035       8      62 ..     389     443 ..     384     455 .. 0.90
   6 ?    3.0   0.1      0.12   1.1e+02       3      31 ..     679     707 ..     678     721 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.085
       TPR_9  4 iaireedweralavverllllaPddpeerrdRGlllaqlGclsaA 48
                ++ +++++ + +++++ +l  +P++ +     +l+   lG+l++A
  EEA20347.1 18 RHYENKQYKKGIKTADQILRKNPNHGDTQAMKALIMSNLGQLEEA 62
                68899********************99999999999999999988 PP

  == domain 2  score: 14.3 bits;  conditional E-value: 3.6e-05
       TPR_9   4 iaireedweralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalap 60 
                 ++  e+++e+a++++   l l P++    rd +ll+ q+ ++ + ++  +++l+  p
  EEA20347.1  86 LYRAEKNYEEAIKAYRFALRLEPESQPIQRDLALLQIQMRDYPGYIQSRNTMLQARP 142
                 6899**************************************988887777777777 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 1.3
       TPR_9  21 llllaPddpeerrdRGlllaqlGclsaAladLeay 55 
                 +l+  P   + +   +++++  G+l +A + L++y
  EEA20347.1 137 MLQARPSFRQNWTALAIAYHLAGNLTEAENVLNTY 171
                 566666666789999*************9999998 PP

  == domain 4  score: -0.0 bits;  conditional E-value: 1.1
       TPR_9  40 aqlGclsaAladLeaylal 58 
                 a++G+l+ Al+ L+++   
  EEA20347.1 198 AESGDLERALEHLDTAGKR 216
                 5566666666666665544 PP

  == domain 5  score: 14.2 bits;  conditional E-value: 3.7e-05
       TPR_9   8 eedweralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalapda 62 
                 ++d ++a+ +ve  + l P++++ ++  ++++ + G+l +A++ +e +  l++++
  EEA20347.1 389 SRDLQKAMDYVEKAISLVPKSVDYHMTKARIYKHYGDLPKAAEVMEEARKLDEKD 443
                 6899***************************************999887777655 PP

  == domain 6  score: 3.0 bits;  conditional E-value: 0.12
       TPR_9   3 aiaireedweralavverllllaPddpee 31 
                 +++ir+++++ al+++    ++++ dp +
  EEA20347.1 679 EVYIRRQKYALALKCLLAAHAIDSLDPTL 707
                 589************98888887777765 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.6   0.0   0.00064      0.61       4      32 ..      34      62 ..      31      63 .. 0.93
   2 !    7.6   0.0    0.0059       5.6       2      34 .]      66      98 ..      65      98 .. 0.94
   3 ?    2.7   0.1      0.21     2e+02      16      33 ..     148     165 ..     141     166 .. 0.92
   4 ?   -1.4   0.0       4.5   4.2e+03      15      34 .]     189     208 ..     183     208 .. 0.69
   5 ?   -0.3   0.1       1.9   1.8e+03       2      15 ..     244     257 ..     243     260 .. 0.84
   6 !    8.7   0.0    0.0026       2.4       3      32 ..     400     429 ..     398     431 .. 0.92

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00064
      TPR_17  4 kaleldPnnadaynnLAelllknGdlmtA 32
                + l+++Pn+ d   ++A +++++G+l++A
  EEA20347.1 34 QILRKNPNHGDTQAMKALIMSNLGQLEEA 62
                6799***********************98 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0059
      TPR_17  2 ylkaleldPnnadaynnLAelllknGdlmtArq 34
                 + al++d ++ + ++  + l++  +++++A++
  EEA20347.1 66 AKTALKNDMKSHVCWHVFGLLYRAEKNYEEAIK 98
                689****************************85 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.21
      TPR_17  16 ynnLAelllknGdlmtAr 33 
                 ++ LA +++ +G+l +A+
  EEA20347.1 148 WTALAIAYHLAGNLTEAE 165
                 999***********9997 PP

  == domain 4  score: -1.4 bits;  conditional E-value: 4.5
      TPR_17  15 aynnLAelllknGdlmtArq 34 
                 a  ++ ++ ++ Gdl++A++
  EEA20347.1 189 AVLYKNTIIAESGDLERALE 208
                 444445555699****9975 PP

  == domain 5  score: -0.3 bits;  conditional E-value: 1.9
      TPR_17   2 ylkaleldPnnada 15 
                 y   l+++P n+  
  EEA20347.1 244 YAALLDRNPENSHY 257
                 8889*******965 PP

  == domain 6  score: 8.7 bits;  conditional E-value: 0.0026
      TPR_17   3 lkaleldPnnadaynnLAelllknGdlmtA 32 
                 +ka+ l P+++d +  +A+++++ Gdl +A
  EEA20347.1 400 EKAISLVPKSVDYHMTKARIYKHYGDLPKA 429
                 89***********************98777 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       5.8   5.4e+03       7      13 ..      56      62 ..      55      71 .. 0.80
   2 !   20.6   0.2   2.8e-07   0.00026       1      37 [.      84     120 ..      84     124 .. 0.85
   3 ?   -3.3   0.0       8.1   7.6e+03       3      13 ..     154     164 ..     152     169 .. 0.78
   4 ?    1.6   0.0      0.23   2.2e+02       6      20 ..     199     213 ..     196     218 .. 0.90
   5 ?    0.9   0.0       0.4   3.8e+02      18      31 ..     400     413 ..     386     422 .. 0.84
   6 ?    0.3   0.1      0.59   5.6e+02       3      29 ..     419     445 ..     417     452 .. 0.82
   7 !    8.5   0.1    0.0017       1.6       3      33 ..     680     710 ..     679     711 .. 0.92

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 5.8
      TPR_11  7 qGkyeeA 13
                +G++eeA
  EEA20347.1 56 LGQLEEA 62
                699**99 PP

  == domain 2  score: 20.6 bits;  conditional E-value: 2.8e-07
      TPR_11   1 GdayyeqGkyeeAieaYkkAlkldPdnaeayynLGla 37 
                 G +y++  +yeeAi+aY+ Al+l P++  +   L+l+
  EEA20347.1  84 GLLYRAEKNYEEAIKAYRFALRLEPESQPIQRDLALL 120
                 789**********************987666666665 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 8.1
      TPR_11   3 ayyeqGkyeeA 13 
                 ay+  G+++eA
  EEA20347.1 154 AYHLAGNLTEA 164
                 68888999998 PP

  == domain 4  score: 1.6 bits;  conditional E-value: 0.23
      TPR_11   6 eqGkyeeAieaYkkA 20 
                 e G++e A+e++ +A
  EEA20347.1 199 ESGDLERALEHLDTA 213
                 78*********9988 PP

  == domain 5  score: 0.9 bits;  conditional E-value: 0.4
      TPR_11  18 kkAlkldPdnaeay 31 
                 +kA+ l P++++ +
  EEA20347.1 400 EKAISLVPKSVDYH 413
                 79**********99 PP

  == domain 6  score: 0.3 bits;  conditional E-value: 0.59
      TPR_11   3 ayyeqGkyeeAieaYkkAlkldPdnae 29 
                 +y   G++++A e+ ++A kld+++  
  EEA20347.1 419 IYKHYGDLPKAAEVMEEARKLDEKDRY 445
                 666679****************99855 PP

  == domain 7  score: 8.5 bits;  conditional E-value: 0.0017
      TPR_11   3 ayyeqGkyeeAieaYkkAlkldPdnaeayyn 33 
                 +y  ++ky  A++++ +A ++d+ +++++  
  EEA20347.1 680 VYIRRQKYALALKCLLAAHAIDSLDPTLHIQ 710
                 6999**********************99965 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.1     0.097        92       5      29 ..      47      71 ..      44      73 .. 0.85
   2 !   19.4   0.0   8.5e-07    0.0008       4      33 ..      80     109 ..      78     110 .. 0.94
   3 ?    2.8   0.1      0.18   1.7e+02       4      25 ..     148     169 ..     146     173 .. 0.88
   4 !    8.4   0.5    0.0028       2.7       5      34 .]     225     254 ..     221     254 .. 0.91
   5 ?    5.6   0.1     0.024        22      14      31 ..     389     406 ..     378     409 .. 0.86
   6 ?    5.3   0.1     0.028        26       3      34 .]     412     443 ..     410     443 .. 0.91
   7 ?   -2.6   1.2       9.8   9.3e+03      18      29 ..     593     604 ..     591     624 .. 0.71
   8 ?   -1.9   0.1         6   5.7e+03      10      27 ..     680     697 ..     679     701 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.097
                HHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8  5 ynlgsiylklgdyeeAkeyyekale 29
                 ++++i ++lg++eeA    + al+
  EEA20347.1 47 AMKALIMSNLGQLEEAFVLAKTALK 71
                6899999*********988888887 PP

  == domain 2  score: 19.4 bits;  conditional E-value: 8.5e-07
                 HHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   4 yynlgsiylklgdyeeAkeyyekaleldpd 33 
                 ++  g++y+  ++yeeA+++y+ al+l+p+
  EEA20347.1  80 WHVFGLLYRAEKNYEEAIKAYRFALRLEPE 109
                 8999***********************996 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.18
                 HHHHHHHHHHTT-HHHHHHHHH CS
       TPR_8   4 yynlgsiylklgdyeeAkeyye 25 
                 +  l+ +y+  g++ eA+ +++
  EEA20347.1 148 WTALAIAYHLAGNLTEAENVLN 169
                 899***************9987 PP

  == domain 4  score: 8.4 bits;  conditional E-value: 0.0028
                 HHHHHHHHHTT-HHHHHHHHHHHHHHHHH. CS
       TPR_8   5 ynlgsiylklgdyeeAkeyyekaleldpdn 34 
                  ++++ +l l ++ eA+++y   l+ +p+n
  EEA20347.1 225 EMKADYLLRLDRKAEAEAAYAALLDRNPEN 254
                 58999***********************86 PP

  == domain 5  score: 5.6 bits;  conditional E-value: 0.024
                 TT-HHHHHHHHHHHHHHH CS
       TPR_8  14 lgdyeeAkeyyekaleld 31 
                   d+++A+ y eka++l 
  EEA20347.1 389 SRDLQKAMDYVEKAISLV 406
                 6799***********985 PP

  == domain 6  score: 5.3 bits;  conditional E-value: 0.028
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH. CS
       TPR_8   3 ayynlgsiylklgdyeeAkeyyekaleldpdn 34 
                 +++ +++iy+  gd+ +A e++e+a +ld+++
  EEA20347.1 412 YHMTKARIYKHYGDLPKAAEVMEEARKLDEKD 443
                 67889********************9999875 PP

  == domain 7  score: -2.6 bits;  conditional E-value: 9.8
                 HHHHHHHHHHHH CS
       TPR_8  18 eeAkeyyekale 29 
                 ee k++++ka +
  EEA20347.1 593 EERKKAIKKAKK 604
                 666677776644 PP

  == domain 8  score: -1.9 bits;  conditional E-value: 6
                 HHHHTT-HHHHHHHHHHH CS
       TPR_8  10 iylklgdyeeAkeyyeka 27 
                 +y+  ++y  A +++  a
  EEA20347.1 680 VYIRRQKYALALKCLLAA 697
                 6899999******99877 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.2      0.17   1.6e+02      11      34 .]      19      42 ..      19      42 .. 0.93
   2 ?    0.2   0.0      0.83   7.9e+02      13      29 ..      55      71 ..      48      73 .. 0.84
   3 !   23.3   0.5   4.1e-08   3.9e-05       8      33 ..      84     109 ..      84     110 .. 0.96
   4 ?    3.9   0.1     0.056        53       4      21 ..     148     165 ..     147     169 .. 0.92
   5 ?    0.4   0.0      0.72   6.8e+02      14      27 ..     200     213 ..     198     213 .. 0.83
   6 ?   -0.5   1.4       1.3   1.2e+03      11      34 .]     231     254 ..     227     254 .. 0.86
   7 !    7.6   0.0    0.0038       3.6      11      33 ..     386     408 ..     385     409 .. 0.92
   8 ?    4.0   0.1     0.051        49       3      33 ..     412     442 ..     410     443 .. 0.87
   9 ?   -1.5   0.1       2.8   2.6e+03       8      22 ..     496     510 ..     491     510 .. 0.87
  10 ?    3.3   0.4     0.082        78      10      31 ..     680     701 ..     679     702 .. 0.88

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.17
                HHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1 11 yfklgkydeAleyyekALelnPnn 34
                ++++++y++ ++  ++ L+ nPn+
  EEA20347.1 19 HYENKQYKKGIKTADQILRKNPNH 42
                5889******************97 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.83
                HTT-HHHHHHHHHHHHH CS
       TPR_1 13 klgkydeAleyyekALe 29
                +lg+++eA    + AL+
  EEA20347.1 55 NLGQLEEAFVLAKTALK 71
                79******999999998 PP

  == domain 3  score: 23.3 bits;  conditional E-value: 4.1e-08
                 HHHHHHTT-HHHHHHHHHHHHHHSTT CS
       TPR_1   8 GnayfklgkydeAleyyekALelnPn 33 
                 G++y+  ++y+eA+++y+ AL+l+P+
  EEA20347.1  84 GLLYRAEKNYEEAIKAYRFALRLEPE 109
                 89***********************7 PP

  == domain 4  score: 3.9 bits;  conditional E-value: 0.056
                 HHHHHHHHHHTT-HHHHH CS
       TPR_1   4 lynlGnayfklgkydeAl 21 
                 +  l+ ay+  g++ eA+
  EEA20347.1 148 WTALAIAYHLAGNLTEAE 165
                 788**************7 PP

  == domain 5  score: 0.4 bits;  conditional E-value: 0.72
                 TT-HHHHHHHHHHH CS
       TPR_1  14 lgkydeAleyyekA 27 
                  g+++ Ale+ + A
  EEA20347.1 200 SGDLERALEHLDTA 213
                 5999*****98876 PP

  == domain 6  score: -0.5 bits;  conditional E-value: 1.3
                 HHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1  11 yfklgkydeAleyyekALelnPnn 34 
                 +++l +  eA+++y   L  nP+n
  EEA20347.1 231 LLRLDRKAEAEAAYAALLDRNPEN 254
                 67788999******9999999987 PP

  == domain 7  score: 7.6 bits;  conditional E-value: 0.0038
                 HHHTT-HHHHHHHHHHHHHHSTT CS
       TPR_1  11 yfklgkydeAleyyekALelnPn 33 
                 y+   ++++A +y ekA++l P+
  EEA20347.1 386 YYLSRDLQKAMDYVEKAISLVPK 408
                 88999**************9886 PP

  == domain 8  score: 4.0 bits;  conditional E-value: 0.051
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHSTT CS
       TPR_1   3 alynlGnayfklgkydeAleyyekALelnPn 33 
                  +  ++ +y + g++ +A e  e+A +l+++
  EEA20347.1 412 YHMTKARIYKHYGDLPKAAEVMEEARKLDEK 442
                 6778999*************99999999987 PP

  == domain 9  score: -1.5 bits;  conditional E-value: 2.8
                 HHHHHHTT-HHHHHH CS
       TPR_1   8 GnayfklgkydeAle 22 
                 G  y++++k+  Al+
  EEA20347.1 496 GESYLRQKKLGLALK 510
                 889******999986 PP

  == domain 10  score: 3.3 bits;  conditional E-value: 0.082
                 HHHHTT-HHHHHHHHHHHHHHS CS
       TPR_1  10 ayfklgkydeAleyyekALeln 31 
                 +y + +ky  Al++   A  ++
  EEA20347.1 680 VYIRRQKYALALKCLLAAHAID 701
                 68999*********99998887 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.0      0.31     3e+02      16      56 ..      22      61 ..      18      73 .. 0.69
   2 !    9.5   0.3    0.0012       1.1      10      31 ..      84     105 ..      78     111 .. 0.68
   3 ?    6.5   0.1     0.011        10      50      71 ..     150     171 ..     146     177 .. 0.83
   4 ?    5.3   0.9     0.025        23      26      73 ..     203     249 ..     196     253 .. 0.81
   5 ?    3.5   0.1     0.093        88      42      75 ..     371     406 ..     363     408 .. 0.77
   6 ?    6.5   0.7     0.011        10      16      76 ..     389     441 ..     373     442 .. 0.58
   7 ?    1.7   0.0      0.33   3.1e+02      10      35 ..     496     521 ..     492     526 .. 0.87
   8 ?    3.9   0.1      0.07        66      11      33 ..     679     701 ..     679     712 .. 0.90

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.31
      TPR_12 16 lgrydeAlellekaleiarrllGpdhpltattlrnLgrlyr 56
                 ++y + ++  ++ l+     +G++ +  a ++ nLg+l +
  EEA20347.1 22 NKQYKKGIKTADQILRKN-PNHGDTQAMKALIMSNLGQLEE 61
                667777777777776666.6677777777778888877754 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.0012
      TPR_12  10 aavlrrlgrydeAlellekale 31 
                 ++++r+ ++y+eA++ ++ al+
  EEA20347.1  84 GLLYRAEKNYEEAIKAYRFALR 105
                 5667777777777777776665 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.011
      TPR_12  50 nLgrlyralgryeeAlelleea 71 
                 +L+++y+++g++ eA++ l+  
  EEA20347.1 150 ALAIAYHLAGNLTEAENVLNTY 171
                 79999**********9999865 PP

  == domain 4  score: 5.3 bits;  conditional E-value: 0.025
      TPR_12  26 lekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleeala 73 
                 le+ale    + G+   ++++++   ++++++l+r +eA++++   l+
  EEA20347.1 203 LERALEHLDTA-GKRCSDVLAVMEMKADYLLRLDRKAEAEAAYAALLD 249
                 56777777443.7778889**********************9987766 PP

  == domain 5  score: 3.5 bits;  conditional E-value: 0.093
      TPR_12  42 pltattlrnLgrly.r.algryeeAlelleealaia 75 
                   +a+t + L++ y + ++ ++++A ++ e+a+ + 
  EEA20347.1 371 MFEASTFYFLAQHYnYyLSRDLQKAMDYVEKAISLV 406
                 56788888899986642779************9875 PP

  == domain 6  score: 6.5 bits;  conditional E-value: 0.011
      TPR_12  16 lgrydeAlellekaleia.rrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                   ++++A ++ eka+ ++ +++  ++h        + +r+y   g++ +A e  eea +++e
  EEA20347.1 389 SRDLQKAMDYVEKAISLVpKSV--DYH-------MTKARIYKHYGDLPKAAEVMEEARKLDE 441
                 4457777777777777774444..444.......4556666666666666666666666655 PP

  == domain 7  score: 1.7 bits;  conditional E-value: 0.33
      TPR_12  10 aavlrrlgrydeAlellekaleiarr 35 
                 ++ ++r++++  Al+ ++++++i+  
  EEA20347.1 496 GESYLRQKKLGLALKRFHAVYNIFDV 521
                 68899***************999865 PP

  == domain 8  score: 3.9 bits;  conditional E-value: 0.07
      TPR_12  11 avlrrlgrydeAlellekaleia 33 
                 +v+ r+++y+ Al++l +a++i 
  EEA20347.1 679 EVYIRRQKYALALKCLLAAHAID 701
                 5899***************9996 PP

>> TPR_MalT  MalT-like TPR region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.1     0.036        34       1      64 [.      43     101 ..      43     126 .. 0.70
   2 !    6.0   0.0    0.0072       6.8      45     104 ..     150     211 ..     136     218 .. 0.72
   3 !    7.4   0.0    0.0025       2.4     137     209 ..     391     455 ..     381     474 .. 0.68

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.036
    TPR_MalT   1 geiaalrAllaiasgdaeralelArqALallpeddllariaatavlGeasllqGdleaAlqalq 64 
                 g ++a++Al+  + g+ e+a  lA+ AL+   ++ + +      v G  +  + + e+A +a++
  EEA20347.1  43 GDTQAMKALIMSNLGQLEEAFVLAKTALKNDMKSHVCW-----HVFGLLYRAEKNYEEAIKAYR 101
                 6789***********************97544444333.....233555555555555555555 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.0072
    TPR_MalT  45 vlGeasllqGdleaAlqalqeaeklarqadslhv..allallqqaeilvaqGrLheAletye 104
                 +l+ a++l+G+l++A+++l++ e++++     +      a+l+   i  + G+L+ Ale+  
  EEA20347.1 150 ALAIAYHLAGNLTEAENVLNTYEETLKTPPPRTDmeHSEAVLYKNTIIAESGDLERALEHLD 211
                 46789999999999999999999888655444432235666677777777788888877765 PP

  == domain 3  score: 7.4 bits;  conditional E-value: 0.0025
    TPR_MalT 137 dLeeAeqhlqeGielleqlepeaaldayvllarialaqGdleeAetllekaeelaresnfhvdwlanaeevrv 209
                 dL++A ++++++i l+ +      +d  ++ ari+   Gdl +A++++e+a +l +++++    +++a ++r+
  EEA20347.1 391 DLQKAMDYVEKAISLVPKS-----VDYHMTKARIYKHYGDLPKAAEVMEEARKLDEKDRY---INTKAAKYRL 455
                 5555555555555555554.....777777777777777777777777777777777777...3444555555 PP

>> TPR_4  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0         9   8.5e+03       6      20 ..      48      62 ..      45      62 .. 0.77
   2 !    9.3   0.0     0.002       1.9       6      24 ..     150     168 ..     148     170 .. 0.90
   3 ?    3.4   0.1      0.16   1.5e+02      13      25 ..     199     211 ..     197     212 .. 0.88
   4 ?    2.2   1.1      0.42     4e+02       7      24 ..     227     244 ..     221     246 .. 0.84
   5 ?    0.5   0.0       1.4   1.3e+03       8      26 .]     417     435 ..     412     435 .. 0.80

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 9
       TPR_4  6 aLArallalGdldeA 20
                + A  +  lG+l+eA
  EEA20347.1 48 MKALIMSNLGQLEEA 62
                567777789****99 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.002
       TPR_4   6 aLArallalGdldeArall 24 
                 aLA a++++G+l eA+ +l
  EEA20347.1 150 ALAIAYHLAGNLTEAENVL 168
                 8**************9876 PP

  == domain 3  score: 3.4 bits;  conditional E-value: 0.16
       TPR_4  13 alGdldeAralle 25 
                 + Gdl++A+++l+
  EEA20347.1 199 ESGDLERALEHLD 211
                 67*********97 PP

  == domain 4  score: 2.2 bits;  conditional E-value: 0.42
       TPR_4   7 LArallalGdldeArall 24 
                  A  ll+l + +eA+a+ 
  EEA20347.1 227 KADYLLRLDRKAEAEAAY 244
                 6899***********986 PP

  == domain 5  score: 0.5 bits;  conditional E-value: 1.4
       TPR_4   8 ArallalGdldeAraller 26 
                 Ar + + Gdl+ A++++e+
  EEA20347.1 417 ARIYKHYGDLPKAAEVMEE 435
                 6666666*********996 PP

>> TPR_3  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   0.1    0.0023       2.2      14      35 ..      90     109 ..      80     109 .. 0.84
   2 ?    5.7   0.0     0.016        15       6      23 ..     150     167 ..     147     172 .. 0.89
   3 ?   -1.0   0.4         2   1.9e+03       9      23 ..     384     398 ..     384     398 .. 0.90

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0023
                 TT-HHHHHHH..HHHHHHH-TT CS
       TPR_3  14 kkkyqeArelfsYallaildke 35 
                  k+y+eA+ +  Y+++  l++e
  EEA20347.1  90 EKNYEEAIKA--YRFALRLEPE 109
                 69********..99**988765 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.016
                 HHHHHHHHTT-HHHHHHH CS
       TPR_3   6 syAaefynkkkyqeArel 23 
                 ++A ++++ ++++eA+++
  EEA20347.1 150 ALAIAYHLAGNLTEAENV 167
                 89**************98 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 2
                 HHHHHTT-HHHHHHH CS
       TPR_3   9 aefynkkkyqeArel 23 
                 + +y++ ++q+A ++
  EEA20347.1 384 YNYYLSRDLQKAMDY 398
                 679*********998 PP

>> TPR_6  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.037        35       3      33 .]      12      42 ..      10      42 .. 0.86
   2 ?   -2.2   0.1       9.3   8.8e+03       7      28 ..      50      71 ..      46      72 .. 0.73
   3 ?    9.0   0.2    0.0025       2.3       7      33 .]      84     110 ..      84     110 .. 0.91
   4 ?   -2.1   0.0       8.8   8.3e+03       6      23 ..     151     168 ..     151     172 .. 0.80
   5 ?   -1.6   0.0       6.1   5.8e+03      13      25 ..     195     212 ..     189     216 .. 0.68
   6 ?    4.8   0.3     0.055        52      11      32 ..     232     253 ..     224     254 .. 0.85
   7 ?    0.8   0.0         1   9.6e+02      18      31 ..     273     287 ..     261     288 .. 0.81
   8 ?    0.3   0.1       1.5   1.4e+03      10      33 .]     386     409 ..     378     409 .. 0.83
   9 ?    0.7   0.0       1.1     1e+03       7      28 ..     417     438 ..     415     439 .. 0.87

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.037
                HHHHHHHHHHHHHHHHHHHHHHHHHHH-TT- CS
       TPR_6  3 lyklalsyrklgdtdkAlealerlikeYPdS 33
                l+++   +++ +++ k +++ ++++++ P++
  EEA20347.1 12 LFRQVVRHYENKQYKKGIKTADQILRKNPNH 42
                677777788988*****************96 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 9.3
                HHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6  7 alsyrklgdtdkAlealerlik 28
                al + +lg+ ++A  + +  +k
  EEA20347.1 50 ALIMSNLGQLEEAFVLAKTALK 71
                6777888999999777666665 PP

  == domain 3  score: 9.0 bits;  conditional E-value: 0.0025
                 HHHHHHHHHHHHHHHHHHHHHHH-TT- CS
       TPR_6   7 alsyrklgdtdkAlealerlikeYPdS 33 
                 +l+yr+ +++++A++a++  ++  P+S
  EEA20347.1  84 GLLYRAEKNYEEAIKAYRFALRLEPES 110
                 799***99**********999988887 PP

  == domain 4  score: -2.1 bits;  conditional E-value: 8.8
                 HHHHHHHHHHHHHHHHHH CS
       TPR_6   6 lalsyrklgdtdkAleal 23 
                 la +y  +g+ ++A   l
  EEA20347.1 151 LAIAYHLAGNLTEAENVL 168
                 688999999999997766 PP

  == domain 5  score: -1.6 bits;  conditional E-value: 6.1
                 H.....HHHHHHHHHHHH CS
       TPR_6  13 l.....gdtdkAlealer 25 
                 +     gd ++Ale l+ 
  EEA20347.1 195 TiiaesGDLERALEHLDT 212
                 455555899***998875 PP

  == domain 6  score: 4.8 bits;  conditional E-value: 0.055
                 HHHHHHHHHHHHHHHHHHH-TT CS
       TPR_6  11 rklgdtdkAlealerlikeYPd 32 
                 ++l+++++A +a+  l+++ P+
  EEA20347.1 232 LRLDRKAEAEAAYAALLDRNPE 253
                 457899**************97 PP

  == domain 7  score: 0.8 bits;  conditional E-value: 1
                 HHHH.HHHHHHHH-T CS
       TPR_6  18 kAle.alerlikeYP 31 
                 +Al+  +++l++++P
  EEA20347.1 273 QALKaVYDELVEKFP 287
                 555559********* PP

  == domain 8  score: 0.3 bits;  conditional E-value: 1.5
                 HHH.HHHHHHHHHHHHHHHHH-TT- CS
       TPR_6  10 yrk.lgdtdkAlealerlikeYPdS 33 
                 y+    d +kA+++ e+ i+  P+S
  EEA20347.1 386 YYLsR-DLQKAMDYVEKAISLVPKS 409
                 66635.9*******99999999987 PP

  == domain 9  score: 0.7 bits;  conditional E-value: 1.1
                 HHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   7 alsyrklgdtdkAlealerlik 28 
                 a+ y+  gd  kA e +e+ +k
  EEA20347.1 417 ARIYKHYGDLPKAAEVMEEARK 438
                 78999978********998765 PP

>> Fis1_TPR_C  Fis1 C-terminal tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.1     0.001      0.95      11      46 ..      19      54 ..      17      58 .. 0.92
   2 ?    3.6   0.3     0.075        71      15      34 ..      91     110 ..      87     115 .. 0.90
   3 ?   -1.9   0.2       3.9   3.6e+03      11      29 ..     386     404 ..     378     408 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.001
                HHHHT-HHHHHHHHHHHHHHTTS-HHHHHHHHHHHH CS
  Fis1_TPR_C 11 hyklgeYseArryvdalLeiEPenrQaqsLkelied 46
                hy  ++Y++  + +d++L++ P+    q+ k+li +
  EEA20347.1 19 HYENKQYKKGIKTADQILRKNPNHGDTQAMKALIMS 54
                8999**********************9999999965 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.075
                 T-HHHHHHHHHHHHHHTTS- CS
  Fis1_TPR_C  15 geYseArryvdalLeiEPen 34 
                 ++Y+eA +  +  L++EPe 
  EEA20347.1  91 KNYEEAIKAYRFALRLEPES 110
                 79****************95 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 3.9
                 HHHHT-HHHHHHHHHHHHH CS
  Fis1_TPR_C  11 hyklgeYseArryvdalLe 29 
                 +y  ++ ++A+ yv+  ++
  EEA20347.1 386 YYLSRDLQKAMDYVEKAIS 404
                 4556788889999887765 PP

>> Phage_Nu1  Phage DNA packaging protein Nu1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.2      0.18   1.7e+02      60     113 ..     417     469 ..     406     474 .. 0.81
   2 ?    7.4   2.0    0.0036       3.4      83     105 ..     603     625 ..     589     635 .. 0.85

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.18
   Phage_Nu1  60 eklrkeveelraaaeadldpgtieyerrrlikaqadaqelknaeakkevvelel 113
                  ++ k   +l +aae   +   ++ e+ r i+++a +  l+n e++k + ++  
  EEA20347.1 417 ARIYKHYGDLPKAAEVMEEARKLD-EKDRYINTKAAKYRLRNDENEKGLEDMSK 469
                 566788899999999998877776.6899*************999997766665 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0036
   Phage_Nu1  83 eyerrrlikaqadaqelknaeak 105
                 ++e++rl ka+ad+qelk+a a 
  EEA20347.1 603 KKEQQRLEKAEADKQELKKASAA 625
                 57899**************9865 PP

>> DUF2229  CoA enzyme activase uncharacterised domain (DUF2229)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       4.4   4.1e+03      88     125 ..      74     111 ..      63     154 .. 0.71
   2 ?   -3.4   0.1       6.5   6.2e+03     108     131 ..     400     424 ..     384     474 .. 0.48
   3 ?    9.3   0.2   0.00084       0.8     133     171 ..     586     623 ..     539     692 .. 0.80
   4 ?   -0.4   0.1      0.81   7.6e+02     119     165 ..     776     820 ..     750     835 .. 0.52

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 4.4
     DUF2229  88 aneynCpivqglpeviknnleeeikllspvldledkke 125
                  ++ +C  v gl +  ++n ee ik +   l+le +++
  EEA20347.1  74 MKSHVCWHVFGLLYRAEKNYEEAIKAYRFALRLEPESQ 111
                 37788888888888888888778888887777774443 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 6.5
     DUF2229 108 eeeikllspvldle.dkkelakqll 131
                 e+ i+l+++ +d++ +k++++k++ 
  EEA20347.1 400 EKAISLVPKSVDYHmTKARIYKHYG 424
                 4455666666666633334333222 PP

  == domain 3  score: 9.3 bits;  conditional E-value: 0.00084
     DUF2229 133 el.giskkeikkAvekAleaqkafkeelrkkgeelleele 171
                 ++ g++++e kkA++kA ++q++ +++ ++k+ el ++++
  EEA20347.1 586 DMnGMDEEERKKAIKKAKKEQQRLEKAEADKQ-EL-KKAS 623
                 33589*******************98844433.44.4333 PP

  == domain 4  score: -0.4 bits;  conditional E-value: 0.81
     DUF2229 119 dledkkelakqlleelgiskkeikkAvekAleaqkafkeelrkkgee 165
                 + +dk ++ k+++++l++ +++++kAv+ +le ++++k++++ k+ +
  EEA20347.1 776 NPNDKPTCEKEFVSTLDLANTTLEKAVS-GLETLDDWKADAATKQ-A 820
                 3334445555555555555555555542.4444444444433332.1 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (838 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1779  (0.0992247); expected 358.6 (0.02)
Passed bias filter:                      823  (0.0459033); expected 358.6 (0.02)
Passed Vit filter:                        80  (0.00446204); expected 17.9 (0.001)
Passed Fwd filter:                        24  (0.00133861); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              19  [number of targets reported over threshold]
# CPU time: 0.87u 0.32s 00:00:01.19 Elapsed: 00:00:00.53
# Mc/sec: 4776.94
//
Query:       EEA20348.1  [L=215]
Description: caffeine-induced death protein Cid2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.2e-54  183.7   2.8    4.3e-54  183.2   2.8    1.2  1  Cid2      Caffeine-induced death protein 2
  ------ inclusion threshold ------
      0.035   12.8   0.0      0.048   12.3   0.0    1.1  1  SpoVR     SpoVR like protein
       0.68   10.8   3.9         23    5.9   0.1    3.0  3  AIM5      Altered inheritance of mitochondria 5


Domain annotation for each model (and alignments):
>> Cid2  Caffeine-induced death protein 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  183.2   2.8   7.3e-58   4.3e-54       1     159 [.      40     199 ..      40     200 .. 0.98

  Alignments for each domain:
  == domain 1  score: 183.2 bits;  conditional E-value: 7.3e-58
        Cid2   1 CfstselrdfLrlsRaaiDDtItqrLNalstpsrsagfdpsstal........aipkesaCaefleevLfpsWqaRedvieyCakvaesedkedeeaal 91 
                 Cf+ ++lrdfLrlsR++iDD+Itq+LNal tp+r +gf+p+s+ +        + p++++C++f+++vLfpsWq+R+dv++yCa va+s+d+ed++ ++
  EEA20348.1  40 CFNERVLRDFLRLSRSTIDDSITQNLNALLTPAR-EGFNPTSSDIrqlgtqsrRNPSRESCDTFKNNVLFPSWQSRSDVLNYCAMVATSPDPEDPDLVT 137
                 **********************************.9****999999******9889999**************************************** PP

        Cid2  92 keeeeakaaerasvderlDpyaardrleeresrlkeaeklarlvrnerkvEsIvrartwevlkerCge 159
                 ++ e a+++er+ v+erlDpy++r   ++re+r   +e+la+lvrner+vE+I+r+rtw ++++rC++
  EEA20348.1 138 RQVETAREQERV-VNERLDPYSSR--HFPREAR---TESLANLVRNERSVEQIIRTRTWGIVSDRCNS 199
                 ************.***********..*******...******************************86 PP

>> SpoVR  SpoVR like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   8.1e-06     0.048     109     196 ..      99     185 ..      97     204 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 8.1e-06
       SpoVR 109 ndFFknNalFkkttdarkildslalaaerireyeeryGeeeVEklldaalaleelvdrykrkekkkleeeekrkkereeyesqvedlw 196
                 +d FknN+lF ++++ +++l++ a+ a+          +++VE+  ++   ++e +d+y+ ++  +++++e+ ++  ++  ++ve++ 
  EEA20348.1  99 CDTFKNNVLFPSWQSRSDVLNYCAMVATSPDPEDPDLVTRQVETAREQERVVNERLDPYSSRHFPREARTESLANLVRNE-RSVEQII 185
                 899***********************999999999999999999999999999999999997666655555444433333.3455554 PP

>> AIM5  Altered inheritance of mitochondria 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.1    0.0039        23       7      34 ..      61      92 ..      51     105 .. 0.75
   2 ?    2.8   0.1     0.036   2.2e+02       8      34 ..     115     146 ..     111     152 .. 0.65
   3 ?    4.5   0.2      0.01        61       4      29 ..     143     168 ..     140     189 .. 0.62

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0039
        AIM5  7 qtsvlnslidPlppgppparaele....qeer 34
                 t+ ln+l++P+++g  p+++ ++    q +r
  EEA20348.1 61 ITQNLNALLTPAREGFNPTSSDIRqlgtQSRR 92
                5789**************99999877653333 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.036
        AIM5   8 tsvlnsli....dPlppgppparaele.qeer 34 
                 ++vln  +    +P p++p+  ++++e ++e+
  EEA20348.1 115 SDVLNYCAmvatSPDPEDPDLVTRQVEtAREQ 146
                 55666666556448999999988888843333 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.01
        AIM5   4 lRaqtsvlnslidP......lppgppparael 29 
                  R+q +v+n+++dP             ar  +
  EEA20348.1 143 AREQERVVNERLDPyssrhfP----REAR--T 168
                 69**********996544431....2222..1 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (215 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       358  (0.0199677); expected 358.6 (0.02)
Passed bias filter:                      248  (0.0138323); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.40u 0.28s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 1525.05
//
Query:       EEA20349.1  [L=362]
Description: formamidopyrimidine-DNA glycosylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.3e-36  123.3   0.0    1.7e-35  122.1   0.0    1.6  1  Fapy_DNA_glyco  Formamidopyrimidine-DNA glycosylase N-termina
    9.1e-22   76.9   0.0    1.9e-21   75.8   0.0    1.4  1  H2TH            Formamidopyrimidine-DNA glycosylase H2TH doma
     0.0024   16.7   0.0     0.0059   15.4   0.0    1.6  2  FbpA            Fibronectin-binding protein A N-terminus (Fbp
  ------ inclusion threshold ------
      0.038   14.4   0.5      0.091   13.2   0.0    1.9  3  Ribosomal_S13   Ribosomal protein S13/S18


Domain annotation for each model (and alignments):
>> Fapy_DNA_glyco  Formamidopyrimidine-DNA glycosylase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  122.1   0.0   3.7e-39   1.7e-35       1     116 []       1     134 [.       1     134 [. 0.97

  Alignments for each domain:
  == domain 1  score: 122.1 bits;  conditional E-value: 3.7e-39
                     X--HHHHHHHHHHHHHHHTT-EEEEEEE-SSHHHTS....THHHHHTT-.SEEEEEEEEETTEEEEEE..EEEEEEE-TTTEEESS......... CS
  Fapy_DNA_glyco   1 MPElpEVetvrrglrrhllgkkiakvevlkdktlrg....spaafakalkgrkiasvgrrGKyllleldggevlvvhlgmtGrllik........ 83 
                     MPEl+EV+++++++r+hl+gk++a+v++++d+ + g    s+a+f+ka++g+k+  +g++GKy+++++++++++v+h+gmtG+++i+        
      EEA20349.1   1 MPELAEVARIVHFIRKHLVGKTLANVQAQNDDIVYGkvgtSAAEFQKAMQGNKVIGAGQQGKYFWITMSKPPHVVMHFGMTGWMKIRnadtyyyr 95 
                     ****************************99999999***9999*******************************************889999999 PP

                     ...........TTEEEEEEEG..GGEEEEEEETT---EE CS
  Fapy_DNA_glyco  84 ....eaeeeppkhtkvrleld..dgtelaFvDpRrfGrv 116
                         +++e+ppk++k+ le+d  ++te+aFvDpRr++r+
      EEA20349.1  96 ttnaDDKEWPPKYWKFLLETDenPKTEAAFVDPRRLARI 134
                     999999**************9999************986 PP

>> H2TH  Formamidopyrimidine-DNA glycosylase H2TH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.8   0.0   4.3e-25   1.9e-21       2      84 ..     154     238 ..     154     246 .. 0.91

  Alignments for each domain:
  == domain 1  score: 75.8 bits;  conditional E-value: 4.3e-25
                 --BTT..STTS-HHHHHHHHHT--SBHHHHHHCTTTSCS--HHHHHHHHHHTT--TTSBGGGS-HHHHHHHHHHHHHHHHHHHHT CS
        H2TH   2 gpepl..seaftvdalaerlkkkkrkiktlLLDqklvaGlGNiyadEvLfrakihPerlakslskeelellhqeikevlkeaiel 84 
                 gp+p+  ++  t++ l++++k+k+ +ik+lLLDq++++G+GN+  dE+L+ +kihPe+ +++l++e+++ lh++i  v + ++ +
  EEA20349.1 154 GPDPVtdKDILTIEWLQDKIKSKRVPIKALLLDQANISGIGNWMGDEILYHSKIHPEQYSNTLTDEQIKQLHTSIDYVCTTSVGV 238
                 78998444558999**************************************************************999988865 PP

>> FbpA  Fibronectin-binding protein A N-terminus (FbpA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0      0.36   1.6e+03      73      91 ..      11      29 ..       8      34 .. 0.81
   2 !   15.4   0.0   1.3e-06    0.0059     165     240 ..     153     233 ..     144     272 .. 0.78

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.36
                HHHHHHHHTTXEEEEEEEX CS
        FbpA 73 cmlLRkyLkgarivsieql 91
                + ++Rk+L g+ + +++ +
  EEA20349.1 11 VHFIRKHLVGKTLANVQAQ 29
                5689********9999765 PP

  == domain 2  score: 15.4 bits;  conditional E-value: 1.3e-06
                 SXBXTTSXXH.H..HH.HHHHHHS.XXXHHHHH..HHBTTXXHHHHHHHHTTXSSSH...............HHHHHHHHT CS
        FbpA 165 dklnPleaeele..ef.kellskkekdlvkaLv..kafqGlspllaeelleragldketsakelseedlerlyealqelle 240
                 ++++P + +++   e+ ++ ++ k  +++  L+   +++G+++ +  e+l++ ++ +e+  ++l++e++++l++++  +++
  EEA20349.1 153 NGPDPVTDKDILtiEWlQDKIKSKRVPIKALLLdqANISGIGNWMGDEILYHSKIHPEQYSNTLTDEQIKQLHTSIDYVCT 233
                 666666333332133303334447899999998334689***********************************9988776 PP

>> Ribosomal_S13  Ribosomal protein S13/S18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       2.7   1.2e+04      50      78 ..       6      35 ..       5      41 .. 0.56
   2 ?   13.2   0.0     2e-05     0.091      18      60 ..     188     230 ..     173     244 .. 0.89
   3 ?   -3.2   0.1       2.4   1.1e+04      44      53 ..     297     306 ..     280     331 .. 0.61

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 2.7
  Ribosomal_S13 50 eiekieeivenkaqykipnwi.nrqkdikd 78
                   e+ +i++ + ++   k+ + +  +++di  
     EEA20349.1  6 EVARIVHFIRKHLVGKTLANVqAQNDDIVY 35
                   566777777776555555555233344555 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 2e-05
  Ribosomal_S13  18 taikGiGrrkakiilkkadvdedkrigelteeeiekieeiven 60 
                    ++i+GiG+    +il++ ++  ++  + lt+e+i+++++ ++ 
     EEA20349.1 188 ANISGIGNWMGDEILYHSKIHPEQYSNTLTDEQIKQLHTSIDY 230
                    689***********************************99976 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 2.4
  Ribosomal_S13  44 gelteeeiek 53 
                    +e+++e++e 
     EEA20349.1 297 KEISDEDLED 306
                    4455554443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (362 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       701  (0.0390987); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.50u 0.24s 00:00:00.74 Elapsed: 00:00:00.40
# Mc/sec: 2709.43
//
Query:       EEA20350.1  [L=590]
Description: iron-sulfur cluster assembly associated protein Nar1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.4e-53  179.9   0.0    1.3e-52  178.9   0.0    1.5  1  Fe_hyd_lg_C  Iron only hydrogenase large subunit, C-terminal 


Domain annotation for each model (and alignments):
>> Fe_hyd_lg_C  Iron only hydrogenase large subunit, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  178.9   0.0   7.5e-57   1.3e-52       2     243 .]     117     464 ..     116     464 .. 0.86

  Alignments for each domain:
  == domain 1  score: 178.9 bits;  conditional E-value: 7.5e-57
                  EEEEEE-HHHHHHGGGGGT--T-S-HHHHHHHHH..........H.TT-SEEEETHHHHHHHHHHHHHHHHHHH.........HH..TS-SSEE---- CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..........x.xxxxxxxxxxxxxxxxxxxxxxxxxxxx.........xx..xxxxxxxxxxx RF
  Fe_hyd_lg_C   2 kvvvqvAPavrvalgeefglsvaattgklvaalr..........k.lGfdkVfdtafgadltimeeasellerl.........ee..eeklpmitScC 77 
                  ++v++v+P+vr++l+ ++++s +++ +++ + lr             Gf+ V+dt++ +++++   a+e+ e l          +  + k+p+++S+C
   EEA20350.1 117 IFVASVSPQVRASLAATYDISERKAGHMIDQLLRgpqglrnggkHgNGFTWVLDTNVLRQMVLTLAAQEVTEALhtssassgsGKytSPKKPILSSAC 214
                  5799*****************9998888888876443333333234689*************************77776665511666688******* PP

                  HHHHHHHHHH-GGGGGGB--B--HHHHHHHHHHTHHHHH.....GGEEEEEEES-SSHHHHHTSTT-BBTB.........BSS-EEEEHHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxx.........xxxxxxxxxxxxxxxxxx RF
  Fe_hyd_lg_C  78 PgwvkyvekkypellpnlssvkSPqqilgaliKkylaek.....ekivvVsimPCtaKklEaareefksag.........rdvDavlTtrElaellke 161
                  Pgw++y+ek++p++lp+ls  kSPq   g+++K+ l +      ++i ++++mPC++KklEa+ree+++a          rdvD+v+T rEl+ l  +
   EEA20350.1 215 PGWICYAEKTHPHVLPHLSRLKSPQALSGTFVKSILSRTlgiapSQIWHLAVMPCFDKKLEASREELTDAAwsnisdspvRDVDCVITSRELLMLASS 312
                  ************************************999****************************99445668899******************** PP

                  TT--GGGS.............-------TTSSSSSTSS-..................................TTEEEEE.EEE.-TSEEEEEEEESH CS
                  xxxxxxxx.............xxxxxxxxxxxxxxxxxx..................................xxxxxxx.xxx.xxxxxxxxxxxxx RF
  Fe_hyd_lg_C 162 agidlakl.............eeeeldnplgessgagki..................................egvkeae.vel.egktlkvavvnGl 210
                  ++i+l +l             ++ ++d++l + +++ k                                   ++v e + ++  ++  +k+a  +G+
   EEA20350.1 313 RNISLPSLplkslaptyaphfPDPTVDSFLFSHTQTSKQsskygtsggylyyilllhkekhpgsrievqrgrnSDVIEYSlMSEtNEAIMKAARYYGF 410
                  *****9996666666666666666666666555555555899999************************999978888775443144456******** PP

                  HHHHHHHHHH.....................HTTSS--SEEEEESSTTSGGG-T CS
                  xxxxxxxxxx.....................xxxxxxxxxxxxxxxxxxxxxxx RF
  Fe_hyd_lg_C 211 knikkllekl.....................kageakydfiEvmaCpgGCigGg 243
                  +ni++l++k+                     ++  ++y f+EvmaCpgGC +Gg
   EEA20350.1 411 RNIQNLVRKMkparasrlpganrrgaagsgaSSSGLDYAFVEVMACPGGCTNGG 464
                  ****************************999889999****************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (590 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       496  (0.0276647); expected 358.6 (0.02)
Passed bias filter:                      424  (0.0236488); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.45
# Mc/sec: 3945.76
//
Query:       EEA20351.1  [L=82]
Description: metallothionein-I gene transcription activator [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.7e-17   60.3   1.0    1.3e-16   60.0   1.0    1.2  1  DNA_RNApol_7kD   DNA directed RNA polymerase, 7 kDa subunit
     0.0024   17.8   1.5      0.011   15.6   1.5    2.0  1  zinc_ribbon_4    zinc-ribbon domain
     0.0047   16.5   0.8        1.9    8.1   0.1    2.2  2  zf_UBZ           Ubiquitin-Binding Zinc Finger
  ------ inclusion threshold ------
      0.013   15.5   0.8      0.018   15.0   0.8    1.2  1  DZR              Double zinc ribbon
      0.028   14.1   0.2      0.032   13.9   0.2    1.1  1  TackOD1          Thaumarchaeal output domain 1
      0.035   14.1   1.1      0.051   13.6   1.1    1.3  1  ADK_lid          Adenylate kinase, active site lid
      0.035   14.6   0.8        2.6    8.6   0.1    2.2  2  Zn_ribbon_recom  Recombinase zinc beta ribbon domain
      0.044   13.8   0.4      0.053   13.5   0.4    1.1  1  HypA             Hydrogenase/urease nickel incorporation, met
      0.054   13.4   1.3        8.8    6.3   0.1    2.7  3  Nudix_N_2        Nudix N-terminal
      0.054   13.4   0.4        2.6    8.0   0.0    2.3  2  TFIIS_C          Transcription factor S-II (TFIIS)
      0.099   12.4   1.9        1.2    8.9   0.3    2.2  2  zf-C2H2_11       zinc-finger C2H2-type
       0.22   12.4   2.6        2.3    9.1   0.1    2.2  2  Tnp_zf-ribbon_2  DDE_Tnp_1-like zinc-ribbon
       0.24   11.7   2.0        0.3   11.3   0.1    1.9  2  C1_4             TFIIH C1-like domain
       0.72   10.0   4.4        6.8    6.9   0.5    2.1  2  Zn-ribbon_8      Zinc ribbon domain


Domain annotation for each model (and alignments):
>> DNA_RNApol_7kD  DNA directed RNA polymerase, 7 kDa subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.0   1.0     1e-19   1.3e-16       1      32 []      41      72 ..      41      72 .. 0.99

  Alignments for each domain:
  == domain 1  score: 60.0 bits;  conditional E-value: 1e-19
                    -B-SSS--B----SSS----SSS-----B--- CS
  DNA_RNApol_7kD  1 YiCgeCgaevslkkgdpiRCkeCGhRilYKkR 32
                    YiCgeC+a++sl +++ +RC+eCGhRilYK+R
      EEA20351.1 41 YICGECDAKFSLPPNATLRCTECGHRILYKER 72
                    *******************************9 PP

>> zinc_ribbon_4  zinc-ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   1.5   8.7e-06     0.011       4      35 ..      42      67 ..      40      68 .. 0.90

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 8.7e-06
  zinc_ribbon_4  4 tCpsCkakyeiddeklpakgvkvrCskCghvF 35
                    C +C ak++++++      + +rC+ Cgh +
     EEA20351.1 42 ICGECDAKFSLPPN------ATLRCTECGHRI 67
                   599**********6......99********86 PP

>> zf_UBZ  Ubiquitin-Binding Zinc Finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.1   0.1    0.0031         4       2      13 ..      40      51 ..      39      54 .. 0.86
   2 !    8.1   0.1    0.0015       1.9       2      14 ..      57      69 ..      56      73 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0031
      zf_UBZ  2 tylCerCgkeip 13
                 y+C +C+++++
  EEA20351.1 40 RYICGECDAKFS 51
                69*******997 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0015
      zf_UBZ  2 tylCerCgkeipe 14
                t  C +Cg++i+ 
  EEA20351.1 57 TLRCTECGHRILY 69
                678*******985 PP

>> DZR  Double zinc ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.0   0.8   1.4e-05     0.018       8      38 ..      36      67 ..      32      73 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.4e-05
         DZR  8 lppdarfCseCgtklkavaa.edrCpsCgekv 38
                ++++   C+eC +k + +++   rC +Cg+ +
  EEA20351.1 36 VQSSRYICGECDAKFSLPPNaTLRCTECGHRI 67
                4566679*******776655699*****9975 PP

>> TackOD1  Thaumarchaeal output domain 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.2   2.5e-05     0.032     144     176 ..      38      71 ..      30      80 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 2.5e-05
     TackOD1 144 levykCnsCkslfs.epevkarClsCekesesdd 176
                 ++ y+C +C+  fs  p++ +rC++C+++   ++
  EEA20351.1  38 SSRYICGECDAKFSlPPNATLRCTECGHRILYKE 71 
                 57899*****9988357999*******9987665 PP

>> ADK_lid  Adenylate kinase, active site lid
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   1.1     4e-05     0.051       1      30 [.      40      66 ..      40      70 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 4e-05
                EEE-TTT--EEETTTB--SSTTB-TTT--. CS
     ADK_lid  1 RrvCpkCGrsYhvvfnpPkveglCDkCGep 30
                R +C  C + ++    pP +   C +CG  
  EEA20351.1 40 RYICGECDAKFS---LPPNATLRCTECGHR 66
                99**********...9************85 PP

>> Zn_ribbon_recom  Recombinase zinc beta ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.1     0.038        48       6      15 ..      41      50 ..      38      52 .. 0.80
   2 ?    8.6   0.1     0.002       2.6       6      23 ..      58      75 ..      56      80 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.038
  Zn_ribbon_recom  6 lrCgeCGspm 15
                      +CgeC +++
       EEA20351.1 41 YICGECDAKF 50
                     58****9987 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.002
  Zn_ribbon_recom  6 lrCgeCGspmtrrkrkgk 23
                     lrC eCG++  ++ r+++
       EEA20351.1 58 LRCTECGHRILYKERTKR 75
                     8********887777655 PP

>> HypA  Hydrogenase/urease nickel incorporation, metallochaperone, hypA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.4   4.1e-05     0.053      67      95 ..      37      66 ..      31      80 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 4.1e-05
                E--EEEETTTS-EEECHHH.HHS-TTTSSS CS
        HypA 67 vpvkvrCreCgkefeleek.alrCpkCgsa 95
                ++ ++ C eC+++f+l  + +lrC +Cg++
  EEA20351.1 37 QSSRYICGECDAKFSLPPNaTLRCTECGHR 66
                567889*********8876699*****986 PP

>> Nudix_N_2  Nudix N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       2.5   3.2e+03      12      20 ..       6      14 ..       3      15 .. 0.81
   2 ?    5.3   0.1     0.014        18      21      29 ..      39      47 ..      34      48 .. 0.87
   3 ?    6.3   0.1    0.0069       8.8       3      10 ..      60      67 ..      58      74 .. 0.73

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 2.5
                EE--TT-SS CS
   Nudix_N_2 12 lripdgDnr 20
                +++p+ Dn+
  EEA20351.1  6 YQVPALDNQ 14
                899999986 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.014
                -EEEETTTT CS
   Nudix_N_2 21 eRlvCpaCg 29
                 R++C  C+
  EEA20351.1 39 SRYICGECD 47
                6*******7 PP

  == domain 3  score: 6.3 bits;  conditional E-value: 0.0069
                -TTT--B- CS
   Nudix_N_2  3 CsqCGtpv 10
                C++CG+++
  EEA20351.1 60 CTECGHRI 67
                77888775 PP

>> TFIIS_C  Transcription factor S-II (TFIIS)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.1     0.046        59      28      38 ..      40      50 ..      36      51 .. 0.81
   2 ?    8.0   0.0     0.002       2.6      29      37 ..      58      66 ..      53      68 .. 0.81

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.046
     TFIIS_C 28 fykCtkCghrW 38
                 y C +C  ++
  EEA20351.1 40 RYICGECDAKF 50
                69999999887 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.002
     TFIIS_C 29 ykCtkCghr 37
                 +Ct+Cghr
  EEA20351.1 58 LRCTECGHR 66
                68*****98 PP

>> zf-C2H2_11  zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.1     0.065        84       7      15 ..      43      51 ..      37      54 .. 0.82
   2 ?    8.9   0.3   0.00096       1.2       3      11 ..      56      64 ..      55      66 .. 0.88

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.065
  zf-C2H2_11  7 CleCGlcft 15
                C eC  +f+
  EEA20351.1 43 CGECDAKFS 51
                99*****98 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.00096
  zf-C2H2_11  3 stcqCleCG 11
                +t++C+eCG
  EEA20351.1 56 ATLRCTECG 64
                89******9 PP

>> Tnp_zf-ribbon_2  DDE_Tnp_1-like zinc-ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.1    0.0018       2.3      13      23 ..      37      47 ..      31      54 .. 0.80
   2 ?    3.4   0.4      0.11   1.4e+02      15      23 ..      56      64 ..      53      70 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0018
  Tnp_zf-ribbon_2 13 keTriiCqeCd 23
                     + +r+iC eCd
       EEA20351.1 37 QSSRYICGECD 47
                     349*******9 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.11
  Tnp_zf-ribbon_2 15 TriiCqeCd 23
                     ++ +C eC+
       EEA20351.1 56 ATLRCTECG 64
                     688999997 PP

>> C1_4  TFIIH C1-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   0.00024       0.3      18      36 ..      33      51 ..      25      55 .. 0.85
   2 ?   -0.2   0.2      0.94   1.2e+03      25      33 ..      57      65 ..      53      67 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00024
        C1_4 18 deeltssryrCekCkndFC 36
                + +++ssry C++C+ +F 
  EEA20351.1 33 QPQVQSSRYICGECDAKFS 51
                45789***********996 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.94
        C1_4 25 ryrCekCkn 33
                + rC +C +
  EEA20351.1 57 TLRCTECGH 65
                568999965 PP

>> Zn-ribbon_8  Zinc ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   4.4    0.0074       9.4       6      34 ..      41      65 ..      40      67 .. 0.69
   2 ?    6.9   0.5    0.0053       6.8       7      14 ..      59      66 ..      54      75 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0074
  Zn-ribbon_8  6 YrCeeCghefevlqsisdaplta.CPeCgs 34
                 Y C eC+ +f  l     ++ t  C eCg+
   EEA20351.1 41 YICGECDAKFS-LP----PNATLrCTECGH 65
                 88999998888.32....234555999986 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0053
  Zn-ribbon_8  7 rCeeCghe 14
                 rC+eCgh+
   EEA20351.1 59 RCTECGHR 66
                 89999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (82 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       653  (0.0364214); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        80  (0.00446204); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.42u 0.27s 00:00:00.69 Elapsed: 00:00:00.45
# Mc/sec: 551.22
//
Query:       EEA20352.1  [L=430]
Description: anthranilate phosphoribosyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.6e-56  189.2   0.0    4.7e-53  180.4   0.0    2.2  1  Glycos_transf_3  Glycosyl transferase family, a/b domain
    3.2e-06   26.9   0.5    6.4e-06   25.9   0.5    1.5  1  Glycos_trans_3N  Glycosyl transferase family, helical bundle 


Domain annotation for each model (and alignments):
>> Glycos_transf_3  Glycosyl transferase family, a/b domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  180.4   0.0   5.2e-57   4.7e-53       4     253 .]     107     417 ..     104     417 .. 0.93

  Alignments for each domain:
  == domain 1  score: 180.4 bits;  conditional E-value: 5.2e-57
                      BEEEEESS-SSSTHHHHHHHHHHHHHHTT-BEEEEE-STCTTCS-HHHHHCTS.T-..-S.T--HHHHHHHHHHHSEEEEEHHSSSSHHHHHHH CS
  Glycos_transf_3   4 lvDivgTGGdgantfNiStaaaivvAaaGvkvakhgnrsvssksGsaDvLeal.gv..nl.eltpeeveklleevgvgflfapeyhkamkhvap 93 
                      l DivgTGGd ++tfN+St+++i+++a+ + vakhgnrs +s sGsaDvL+++  v  ++   ++++++k+lee++ +flfap++h++mk++ p
       EEA20352.1 107 LCDIVGTGGDSHSTFNVSTTSSIIASAL-LLVAKHGNRSQTSFSGSADVLNCIlPVppKIsAIKANDIAKVLEETNYTFLFAPNFHQGMKYADP 199
                      78*********************99998.78*********************98552267678899**************************** PP

                      HHHHHTT.-SSHHHCHHHHH..T..SEEEEHHHHHHHHTCHSEEEEEEEESTTSSCCS.TSHHHHHHHHHHHHHHHHTT............... CS
  Glycos_transf_3  94 vrrelgirTvfnlLGPLinp..arvkkqllgvyskelaeklaevlkelgveralvvhg.dGldevsllakttvaelkdg............... 169
                      vrr lgirT+fnl+GPL np     +++++gv+ ++l +   e+l+  g+++alv++g + +devs ++ t+ ++l +                
       EEA20352.1 200 VRRGLGIRTIFNLMGPLANPvdWALEARVVGVAYQSLGPIFIEALRLGGSKKALVICGeEDMDEVSCAGPTNCWRLSEYpnpaykpendeggde 293
                      ********************5556899********************9**********999**************9855568888889999*** PP

                      ..............EEEEEEEEEGSSTSSSEEESHHHHSS.HHHHHHHHTTHHTSCHHHHH..HHHHHHHHHHHHHHTTSSSS........... CS
  Glycos_transf_3 170 ..............eiteytlepedfglkraelealegge.pkenaeilkavlegkksaak..rdlvllnagaalvlagkads........... 235
                                    +++ ++l+p+dfg+ ++   ++  ++ pk+nae l ++l+++ + ++  ++ vl+n++a+lv++g +d            
       EEA20352.1 294 ededeeetnprtltKLDIFQLHPKDFGFPTHPITDVYTKKmPKQNAEKLMSILRNELDPEDplMHFVLMNTAALLVTSGICDAetsnmgpgddg 387
                      ***********9999999******************886537*************99998889****************999899********* PP

                      ............HHHHHHHHHHHHHTSHHH CS
  Glycos_transf_3 236 ............lkegvakaeevidsGkAl 253
                                  +kegv++a+ +i+sG+Al
       EEA20352.1 388 kvitergpgggrWKEGVRRARYAITSGQAL 417
                      ****************************95 PP

>> Glycos_trans_3N  Glycosyl transferase family, helical bundle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.9   0.5   7.2e-10   6.4e-06      12      62 ..      28      80 ..      16      81 .. 0.94

  Alignments for each domain:
  == domain 1  score: 25.9 bits;  conditional E-value: 7.2e-10
                     ---HHHHHHHHHHHHTTSS-HHHHHHHHHHHHHH-..--HHHHHHHHHHHHHH CS
  Glycos_trans_3N 12 eLtaeeirfaihgilkgevtdaqiaAfLmAlrlkG..etaeEiaalaeAmres 62
                     + +aeei++a+  i++++++ +q+aA+L+ l+ +G   +a  ia +   mre+
       EEA20352.1 28 QVSAEEIAAAFALIFEDRLSLIQTAALLTLLHSTGkdRDAKVIALCSHRMREA 80
                     579******************************************99999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (430 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       370  (0.020637); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 2798.59
//
Query:       EEA20353.1  [L=343]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    0.00022   21.2   0.5     0.0004   20.4   0.5    1.3  1  VAD1-2         Vitamin A-deficiency (VAD) rat model signallin
    0.00058   20.0   0.1      0.019   15.1   0.1    2.7  1  Ribosomal_L10  Ribosomal protein L10
  ------ inclusion threshold ------
       0.12   12.4   0.0       0.22   11.5   0.0    1.4  1  P22_Tail-4     P22 tail accessory factor


Domain annotation for each model (and alignments):
>> VAD1-2  Vitamin A-deficiency (VAD) rat model signalling
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.5   6.6e-08    0.0004     106     153 ..      31      80 ..       4      94 .. 0.66

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 6.6e-08
      VAD1-2 106 linfAssL.AvAsss.kmdLpnLehmikappqkaeepstepaaqpavdep 153
                    +As+  A Asss  + Lp+Le+m k+p++ a  ps++p  ++  +e+
  EEA20353.1  31 SARYASTAtAAASSSvTVPLPSLEQMKKSPSRTARTPSVQPPSHRRPEER 80 
                 3357776515555553578**********************554444443 PP

>> Ribosomal_L10  Ribosomal protein L10
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.1   3.3e-06     0.019       3      44 ..      78     119 ..      76     230 .. 0.91

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 3.3e-06
                    CCCHCCCCCCCCCCCTTSSEEEEEE-TTS-HHHHHHCCCHHH CS
  Ribosomal_L10   3 kekKeelvkelkellkkyksvvvvdyegltvaqlqelRkklr 44 
                     e++ +l+++ + l+ ++  +v+++ ++l++++++ +R++l 
     EEA20353.1  78 EERRSQLLRQYTSLIRTAPLMVFFQHNNLQSTEWTAIRRELT 119
                    5788999********************************985 PP

>> P22_Tail-4  P22 tail accessory factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   3.6e-05      0.22      73     120 ..     141     188 ..     122     202 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 3.6e-05
                 E---STTHHHHHHHHHHHSTGGGTS---HHHHHHHHHHHHHHTHHHHH CS
  P22_Tail-4  73 sGlsrkavsaviynLalrilsdyaleptakviatakagkeaLlkdtli 120
                 s ++ + +++ i+++alri+  ++ e +ak ia+a++  + Ll+d + 
  EEA20353.1 141 SNVKLQIIQTSIFEVALRIVDYFKPENVAKKIAAAETEEDILLHDLSR 188
                 5667788999*********************************99765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (343 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       507  (0.0282782); expected 358.6 (0.02)
Passed bias filter:                      345  (0.0192426); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.47u 0.30s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 2293.16
//
Query:       EEA20354.1  [L=476]
Description: phosphatidylinositol phospholipase C [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.6e-11   42.8   0.0    5.8e-11   42.2   0.0    1.3  1  PI-PLC-X  Phosphatidylinositol-specific phospholipase C, X do


Domain annotation for each model (and alignments):
>> PI-PLC-X  Phosphatidylinositol-specific phospholipase C, X domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.2   0.0   3.2e-15   5.8e-11      25     144 ..     191     315 ..     168     316 .. 0.84

  Alignments for each domain:
  == domain 1  score: 42.2 bits;  conditional E-value: 3.2e-15
                 H---SS-HHHHHHTT--EEEEEE-........TT.SEEEETTE...EE.EEEHHHHHHHHHHHHHHSTT--EEEEEEETTT-THHHHHHHHHHHHGGGG CS
    PI-PLC-X  25 sessveayrnaLlrGcRcvEidvw.....dgedeepvvlhgyt...ltkkikfrdvleaikdyafktselPvivsLevhcsaeqqekmaeilkeifgdl 115
                  ++++ + +++L++G+R+++i+v+     d ++++++++h  +   lt +  frd l+ ++++++ + ++++i+sL+ +    + +   e l+ i +d+
  EEA20354.1 191 VRCQAVSPKEQLENGVRFFDIRVQpqypdDPSKDDLILVHSAFpisLTGNKYFRDLLNVVNEFLDRNPSETLIISLKREG---TGKATDEQLSRIVRDH 286
                 4678888899**************99998888889999**765222678999**************************99...4556677888899999 PP

                 B-EEETT-.------BCCCCTT-EEEEE. CS
    PI-PLC-X 116 LleeplekeeskelpspeelkgKilikvk 144
                 + +++++++++ + p++ e++gKi++ ++
  EEA20354.1 287 YATPDSRWYTDPRTPTLGEVRGKIVLVRR 315
                 99***********************9887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (476 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       458  (0.0255452); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.26s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 3152.03
//
Query:       EEA20355.1  [L=483]
Description: biotin-dependent 2-oxo acid dehydrogenases acyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.3e-78  262.8   0.5    3.7e-78  262.2   0.5    1.3  1  2-oxoacid_dh   2-oxoacid dehydrogenases acyltransferase (cata
    3.7e-14   52.3   0.0    9.2e-14   51.0   0.0    1.7  1  Biotin_lipoyl  Biotin-requiring enzyme
    1.5e-11   44.4   0.9      3e-11   43.5   0.1    2.0  2  E3_binding     e3 binding domain
  ------ inclusion threshold ------
          1    9.8   4.3       0.25   11.8   0.5    1.9  2  BNIP2          Bcl2-/adenovirus E1B nineteen kDa-interacting 


Domain annotation for each model (and alignments):
>> 2-oxoacid_dh  2-oxoacid dehydrogenases acyltransferase (catalytic domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  262.2   0.5   8.3e-82   3.7e-78       4     232 ..     250     479 ..     247     480 .. 0.96

  Alignments for each domain:
  == domain 1  score: 262.2 bits;  conditional E-value: 8.3e-82
                   XXXXXXXXXXXXXXXXXXXXX.XXXEEEEEEEEE-HHHHHHHHHHHHHHHHTT-----HHHHHHHHHHHHHHH-GGGG-EE.EES...EEEE--SS- CS
  2-oxoacid_dh   4 eervplsgirkaiakrlteskqeiphftlsdevdvtallelrkelkekeakeekakltlldflikavalAlkefPelnasvdeee...keivvkkhv 97 
                   e++ pl++i+++++k++t+s+  iph+ + de++++ + +lr++l +++++++  k+t l+f+ikav+lAl+e+P+lna+vd+ +   +++++++++
    EEA20355.1 250 ESTKPLTHIQSQMFKTMTKSL-IIPHLLYADELNINTMTALRRKLASDRNNSQ--KVTSLAFIIKAVSLALEEYPILNAKVDASDpstPKLIMRANH 343
                   6789*****************.***************************8655..9*************************65554559******** PP

                   -EEEE--------EEEE--GGG--HHHHHHHHHHHHHHHTTT---GGGTSS-SEEEE---------------TT-SEEEEE---.B--TT.STT-HT CS
  2-oxoacid_dh  98 niGvAvatprGLlvPviknadkkslleiakelkelaekaregklkpedleggtftisNlGmlGvtsftPiinppqvaIlgvgrikerpvv.kegelv 193
                   niG+ ++tp+GL+vP+ikn+ +ks+ eia+e+ +l+   +egklkp+d++ggt+t+sN+G++G+t+  P+i p +vaIlgvgr +  pv+ ++g++ 
    EEA20355.1 344 NIGIGMDTPQGLIVPNIKNVGAKSIFEIAAEISRLSALGKEGKLKPADITGGTITVSNIGNIGGTYLAPVIVPTEVAILGVGRSRVLPVFdENGQVT 440
                   ************************************************************************************************* PP

                   ---EEEEEEEEETTT--HHHHHHHHHHHHHTT-HHXXXX CS
  2-oxoacid_dh 194 vrkvmtlslsaDHRvidGaeaarFlntlkkllenpeell 232
                    +++++ls+saDHRvidGa++ar+  ++k+++e+p+++l
    EEA20355.1 441 KGEMVNLSWSADHRVIDGATMARMAGKVKEYVEEPDRML 479
                   *************************************98 PP

>> Biotin_lipoyl  Biotin-requiring enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.0   0.0   2.1e-17   9.2e-14       7      73 .]      54     121 ..      52     121 .. 0.97

  Alignments for each domain:
  == domain 1  score: 51.0 bits;  conditional E-value: 2.1e-17
                    SSEEEEEE..ECSESSSTTCEE-TTSEEEEEECTTEEEEEEBSSSEEEEEESSTTTEEE-TTCEEEEE CS
  Biotin_lipoyl   7 miGesveeg.vvevlvkvGdkVkagqvlaeveamKmemeieapkaGvvkeilvkeGdtvevgdllaki 73 
                    ++Ge ++e  +++++v++G +V++  +l+  +++K++ +i+++ aGv+k+++ + +dtv +g  l+ i
     EEA20355.1  54 DVGEGITEVqIIQWYVEEGAHVEEWKPLCQYQSDKAVDDITSRYAGVIKKLHFQTDDTVPTGRALCDI 121
                    79*************************************************************99876 PP

>> E3_binding  e3 binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.5   0.1   6.7e-15     3e-11       2      36 .]     180     214 ..     179     214 .. 0.98
   2 ?   -3.2   0.1       2.6   1.2e+04      12      23 ..     383     394 ..     380     396 .. 0.72

  Alignments for each domain:
  == domain 1  score: 43.5 bits;  conditional E-value: 6.7e-15
                 BE-HHHHHHHHHCT--TTTS---CTTTBE-HHHHC CS
  E3_binding   2 lAsPaaRklAkelGidLsdvkGtGpgGRItkeDVl 36 
                 lA+Pa+R + k +++++ d+ GtG++GR++keDVl
  EEA20355.1 180 LATPAVRGMLKTHNLNILDIRGTGKDGRVLKEDVL 214
                 69********************************7 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.6
                 HHCT--TTTS-- CS
  E3_binding  12 kelGidLsdvkG 23 
                 ke  + ++d++G
  EEA20355.1 383 KEGKLKPADITG 394
                 677788889974 PP

>> BNIP2  Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.5   5.5e-05      0.25      32      92 ..     103     170 ..      60     197 .. 0.72
   2 ?   -2.4   0.2       1.4   6.2e+03      19      36 ..     231     247 ..     211     259 .. 0.49

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 5.5e-05
       BNIP2  32 p.....ddissledsl.dinvDdletpsdedslevpetlkdleweddlp.akeaeaasesaeslpqys 92 
                 +     dd+  +   l di+vDd + p+++   + ++t++ +e +++    ++++aa ++ e +++ +
  EEA20355.1 103 KlhfqtDDTVPTGRALcDIEVDDAQYPDENAPAQATQTESTIENAEESTtSETSQAADAPVEVISEQK 170
                 144444999999999**************999999988887777766442333333333333333333 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 1.4
       BNIP2  19 sdsdlsqflasvtpddis 36 
                 s + +s++ a+ t++d +
  EEA20355.1 231 SAASASTARAT-TSSDAQ 247
                 22222222222.333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (483 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1060  (0.0591221); expected 358.6 (0.02)
Passed bias filter:                      530  (0.029561); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.43
# Mc/sec: 3399.70
//
Query:       EEA20356.1  [L=239]
Description: thermoresistant gluconokinase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.8e-10   40.4   0.0    1.1e-09   38.9   0.0    1.7  1  AAA_18          AAA domain
    1.7e-09   38.0   0.0      5e-09   36.5   0.0    1.8  2  AAA_33          AAA domain
    5.1e-06   27.0   0.0    7.6e-05   23.1   0.0    2.3  1  AAA_17          AAA domain
    5.4e-06   26.6   0.0    2.2e-05   24.6   0.0    1.9  1  SKI             Shikimate kinase
    0.00025   20.8   0.0    0.00054   19.8   0.0    1.5  1  Cytidylate_kin  Cytidylate kinase
    0.00068   19.5   0.0       0.21   11.4   0.0    2.2  2  dNK             Deoxynucleoside kinase
      0.001   19.3   0.0     0.0021   18.3   0.0    1.5  1  AAA_22          AAA domain
     0.0015   18.9   0.0     0.0027   18.1   0.0    1.5  1  AAA             ATPase family associated with various cellula
     0.0096   15.7   0.0      0.014   15.1   0.0    1.2  1  AAA_30          AAA domain
  ------ inclusion threshold ------
      0.011   15.1   0.0      0.016   14.5   0.0    1.4  1  Zeta_toxin      Zeta toxin
      0.011   16.1   0.0      0.016   15.6   0.0    1.3  1  AAA_16          AAA ATPase domain
      0.014   15.7   0.0      0.022   15.0   0.0    1.4  1  AAA_28          AAA domain
      0.018   15.0   0.0      0.033   14.1   0.0    1.4  1  Rad17           Rad17 P-loop domain
      0.022   14.0   0.0       0.03   13.6   0.0    1.2  1  DUF2075         Uncharacterized conserved protein (DUF2075)
      0.024   13.7   0.0       0.04   13.0   0.0    1.3  1  T2SSE           Type II/IV secretion system protein
      0.026   14.4   0.0      0.046   13.6   0.0    1.4  1  NACHT           NACHT domain
      0.028   14.5   0.0        1.8    8.7   0.0    2.1  2  ADK             Adenylate kinase
      0.032   14.0   0.0       0.11   12.2   0.0    1.8  2  AAA_24          AAA domain
      0.038   14.4   0.0      0.092   13.1   0.0    1.7  1  RNA_helicase    RNA helicase
      0.044   13.5   0.0      0.089   12.5   0.0    1.5  1  RuvB_N          Holliday junction DNA helicase RuvB P-loop do
      0.052   12.9   0.0      0.083   12.3   0.0    1.3  1  Mg_chelatase    Magnesium chelatase, subunit ChlI
      0.066   12.9   0.0       0.12   12.1   0.0    1.3  1  CoaE            Dephospho-CoA kinase
      0.076   12.5   0.0       0.12   11.8   0.0    1.3  1  Thermopsin      Thermopsin
      0.084   12.5   0.0       0.33   10.5   0.1    1.8  2  cobW            CobW/HypB/UreG, nucleotide-binding domain
      0.084   13.4   0.0       0.18   12.3   0.0    1.6  1  ABC_tran        ABC transporter
      0.091   12.6   0.0       0.16   11.9   0.0    1.4  1  APS_kinase      Adenylylsulphate kinase
       0.11   12.3   0.0        0.2   11.4   0.0    1.4  1  AAA_29          P-loop containing region of AAA domain
       0.13   12.6   0.0       0.26   11.6   0.0    1.5  1  AAA_19          AAA domain
       0.13   11.9   0.0       0.25   10.9   0.0    1.5  1  AAA_25          AAA domain
       0.13   12.2   0.1       0.24   11.3   0.1    1.4  1  NTPase_1        NTPase
       0.13   12.0   0.0       0.19   11.4   0.0    1.3  1  PRK             Phosphoribulokinase / Uridine kinase family
       0.13   11.4   0.0       0.21   10.7   0.0    1.2  1  NB-ARC          NB-ARC domain
       0.19   11.2   0.0       0.33   10.4   0.0    1.3  1  PhoH            PhoH-like protein


Domain annotation for each model (and alignments):
>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.9   0.0     2e-12   1.1e-09       2     119 ..      61     191 ..      61     203 .. 0.80

  Alignments for each domain:
  == domain 1  score: 38.9 bits;  conditional E-value: 2e-12
      AAA_18   2 lltGtpGvGKttlakeLskrlgf........gvnlrdvakenglllevdpealdeskrldedkldklldaleenssaleegknlvidghlaeleseaak 92 
                 ++tG++G+GKtt+ak+L+ ++g+        +  +++    ng+ l++ +    + ++  +d    ++d+l + +++ + +k  vi ++ a  ++++++
  EEA20356.1  61 IVTGPAGSGKTTVAKNLQAEMGLpflegddfHPLSNKEKMANGIPLTDADR--WDWLISLRDA---AIDILSKPAANTAPPKG-VIMSCSALKLKYRDV 153
                 79***************9999889899888877777777777777777777..4444444444...55555554444556777.999999999999999 PP

      AAA_18  93 dikk...........vvLtaspeelleRlekRgyeeak 119
                 +++            ++L+a++++l++R++ R  +  k
  EEA20356.1 154 IRVAeyynpslrihfIYLKADEKTLMDRVNGRASHYMK 191
                 999899**************************977665 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.5   0.0   9.2e-12     5e-09       2     124 ..      60     191 ..      59     212 .. 0.79
   2 ?   -1.1   0.0       3.4   1.9e+03      96     115 ..     208     227 ..     191     230 .. 0.78

  Alignments for each domain:
  == domain 1  score: 36.5 bits;  conditional E-value: 9.2e-12
      AAA_33   2 vllvGlpGsGKstlaerllkklgavllssdt.....lrrrlfg....tdqqsktdytrvldrlyqilnelarkalsagrnvildatnlsrrerarflkl 91 
                 +++ G++GsGK+t+a++l ++ g  +l+ d+      ++++++    td ++  +++ ++d +++il++ a+ + +  ++vi     l+ + r+ ++++
  EEA20356.1  60 WIVTGPAGSGKTTVAKNLQAEMGLPFLEGDDfhplsNKEKMANgiplTDADRWDWLISLRDAAIDILSKPAA-NTAPPKGVIMSCSALKLKYRD-VIRV 156
                 7999***************************77765445677788889999999*************99995.788889999988888876665.4555 PP

      AAA_33  92 arrl..gvpvrivvvetdeetlkeRlakRaangdd 124
                 a+ +  + +++ +++++de+tl +R+  Ra +  +
  EEA20356.1 157 AEYYnpSLRIHFIYLKADEKTLMDRVNGRASHYMK 191
                 554400556888******************98633 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 3.4
      AAA_33  96 gvpvrivvvetdeetlkeRl 115
                 +v v++v+v++++++ ++++
  EEA20356.1 208 EVDVLAVDVSVPPDVVQRNV 227
                 46688999999999998886 PP

>> AAA_17  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.1   0.0   1.4e-07   7.6e-05       1     122 [.      63     185 ..      63     194 .. 0.60

  Alignments for each domain:
  == domain 1  score: 23.1 bits;  conditional E-value: 1.4e-07
                 EE-TTSSHHHHHHHHHHHHTEEEEEHHHHHHHHHHTTTSHSSHHHHC....TSHHHHHHHHHHHHHHHHHHHHHSSEEEEEE-SEEEETTEEEESSHHH CS
      AAA_17   1 lGgPGsGKgtqceklvekygfthlsaGdllreeakrgglakardemr....klpleekkelqkeaaekiaeeakkkgvlvdghprikeqagfldglpke 95 
                 +G+ GsGK+t++++l+ ++g+++l+ Gd +    +++++a+     +    +  ++ +++  +++ +  a++a  kgv++   +   + ++   ++   
  EEA20356.1  63 TGPAGSGKTTVAKNLQAEMGLPFLE-GDDFHPLSNKEKMANGIPLTDadrwDWLISLRDAAIDILSKPAANTAPPKGVIMSCSALKLKYRDV-IRV--- 156
                 69***********************.999887777776532222221001111222223333344444445556677777666654444443.233... PP

                 HHHHH..SE...EEEEE--HHHHHHHHHHH CS
      AAA_17  96 vleelkpda...iilleadpeeilerrlkd 122
                   e ++p++   +i+l+ad++++++r+  +
  EEA20356.1 157 -AEYYNPSLrihFIYLKADEKTLMDRVNGR 185
                 .34444433333999999999999998766 PP

>> SKI  Shikimate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.6   0.0     4e-08   2.2e-05       2     107 ..      67     187 ..      66     233 .. 0.77

  Alignments for each domain:
  == domain 1  score: 24.6 bits;  conditional E-value: 4e-08
                 TSSHHHHHHHHHHHHTSEEEEHHHHHHHHHTS-HHHHHHHHHHHHH......HHHHHHHHHHHCCCS....SEEEEE-TTGGGSHHHHHHHH....... CS
         SKI   2 GaGKstvGkllAkklglefiDlDeliekrtgksiaeifeeegeegF......relEsevlkelleee....glViatGGGavlseenrellk....... 83 
                 G+GK+tv+k l  ++gl+f++ D+++   ++ ++a+ +   + +++      r+   ++l + ++++    g++ ++   ++l+ ++r++++       
  EEA20356.1  67 GSGKTTVAKNLQAEMGLPFLEGDDFHPLSNKEKMANGIPLTDADRWdwlislRDAAIDILSKPAANTappkGVIMSC---SALKLKYRDVIRvaeyynp 162
                 9*************************888888888888766544432233225555555666556658996777777...999999999999999**99 PP

                 .HHSEEEEEE--HHHHHHHHHHTTS CS
         SKI  84 .ekgiviyLdvsleellerlkadke 107
                   +  +iyL+++ ++l++r++ + +
  EEA20356.1 163 sLRIHFIYLKADEKTLMDRVNGRAS 187
                 77888***************98877 PP

>> Cytidylate_kin  Cytidylate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.0   9.9e-07   0.00054       4      57 ..      63     116 ..      61     128 .. 0.86

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 9.9e-07
                     E-STTSSHHHHHHHHHHHHT-EEEEHHHHHHHHHHHHHHTT--TT-HHHHHHHH CS
  Cytidylate_kin   4 DGPagsGKssvaralaeklglkyldtgalYRalalaalrrkvdlldeaalvela 57 
                      GPagsGK +va+ l  ++gl +l+   +        + + ++l+d + +  l+
      EEA20356.1  63 TGPAGSGKTTVAKNLQAEMGLPFLEGDDFHPLSNKEKMANGIPLTDADRWDWLI 116
                     6************************99999998888888899999988886665 PP

>> dNK  Deoxynucleoside kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.4   0.0   0.00038      0.21       3      28 ..      62      87 ..      60     123 .. 0.87
   2 ?    6.3   0.0     0.014       7.5     124     150 ..     166     193 ..     138     234 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00038
                EEESTTSSHHHHHHHHHCCSTCEEEE CS
         dNK  3 veGnIgaGKstlvklLskklgvkvfe 28
                v G+ g+GK+t++k L+ ++g +++e
  EEA20356.1 62 VTGPAGSGKTTVAKNLQAEMGLPFLE 87
                88*****************9987765 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.014
                 SEEEEEE--HHHHHHHHHHCTTCCCT.T CS
         dNK 124 dlliYLkasletclerikkRgreeek.k 150
                  ++iYLka+ +t++ r++ R+ ++ k +
  EEA20356.1 166 IHFIYLKADEKTLMDRVNGRASHYMKgN 193
                 579*****************98876643 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   3.9e-06    0.0021       5      28 ..      57      80 ..      53      93 .. 0.90

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 3.9e-06
      AAA_22  5 agilvvtGesGtGKTtllrrlleq 28
                + i +vtG++G+GKTt++++l+ +
  EEA20356.1 57 QHIWIVTGPAGSGKTTVAKNLQAE 80
                56789***************9875 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   4.9e-06    0.0027       2      28 ..      61      87 ..      60     135 .. 0.92

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 4.9e-06
                EEESSTTSSHHHHHHHHHHHHTHEEEE CS
         AAA  2 llyGppGtGKTllakavakelgvefle 28
                +++Gp G GKT++ak +  e+g +fle
  EEA20356.1 61 IVTGPAGSGKTTVAKNLQAEMGLPFLE 87
                689********************9997 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   2.6e-05     0.014      19      40 ..      58      79 ..      53     103 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 2.6e-05
      AAA_30 19 rvavltGpAGtGKttalkalre 40
                 + ++tGpAG+GKtt+ k l++
  EEA20356.1 58 HIWIVTGPAGSGKTTVAKNLQA 79
                5779************999864 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.0     3e-05     0.016       5      57 ..      45      94 ..      41     125 .. 0.67

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 3e-05
  Zeta_toxin  5 lkdkk.ypsqerPklillgGqpGAGKselaellkdelerqgnvvrldpDdlRel 57
                 ++ + +p+++   + ++ G  G+GK+++a+ l++e+    +   l++Dd+ +l
  EEA20356.1 45 MRNHNmNPDSSLQHIWIVTGPAGSGKTTVAKNLQAEM----GLPFLEGDDFHPL 94
                56666667777888999*******************9....4455667766544 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.6   0.0     3e-05     0.016      25      48 ..      58      81 ..      46     127 .. 0.86

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 3e-05
      AAA_16 25 elvllsGesGvGKsslvrellral 48
                ++ +++G++G+GK+++++ l+ ++
  EEA20356.1 58 HIWIVTGPAGSGKTTVAKNLQAEM 81
                6779*************9998755 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.0   0.0   4.1e-05     0.022       3      27 ..      61      86 ..      59     141 .. 0.80

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 4.1e-05
      AAA_28  3 vitGgestGKTtlleaLaar.gypvv 27
                ++tG+ ++GKTt++++L+a+ g p +
  EEA20356.1 61 IVTGPAGSGKTTVAKNLQAEmGLPFL 86
                68****************87688876 PP

>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   6.1e-05     0.033      44      73 ..      56      85 ..      44     105 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 6.1e-05
       Rad17 44 kkriLLisGPsGCgkstvvkvLskelgikl 73
                 ++i +++GP+G gk+tv k L  e+g  +
  EEA20356.1 56 LQHIWIVTGPAGSGKTTVAKNLQAEMGLPF 85
                45699*****************99998765 PP

>> DUF2075  Uncharacterized conserved protein (DUF2075)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.0   5.6e-05      0.03       2      25 ..      58      81 ..      57     105 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 5.6e-05
     DUF2075  2 avvlVtGvaGtGKtvvllnllael 25
                ++ +VtG aG+GKt v+ nl ae+
  EEA20356.1 58 HIWIVTGPAGSGKTTVAKNLQAEM 81
                789*****************9987 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   7.4e-05      0.04     129     149 ..      57      77 ..      47      83 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 7.4e-05
       T2SSE 129 rglilvsGgTgsGKttllyal 149
                 + + +v+G+ gsGKtt++  l
  EEA20356.1  57 QHIWIVTGPAGSGKTTVAKNL 77 
                 66789***********98665 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.0   8.4e-05     0.046       3      25 ..      60      82 ..      58      95 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 8.4e-05
                EEEEC-TTTCHHHHHHHHHHHHC CS
       NACHT  3 vilqGeaGsGKTtLlqklalawa 25
                 i++G+aGsGKTt ++ l  ++ 
  EEA20356.1 60 WIVTGPAGSGKTTVAKNLQAEMG 82
                689*************9988765 PP

>> ADK  Adenylate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.0    0.0033       1.8       1      30 [.      62      91 ..      62     128 .. 0.86
   2 ?    4.0   0.0     0.088        48     106     135 ..     168     238 ..     150     239 .] 0.88

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0033
                EEESTTSSHHHHHHHHHHHHTSEEEEHHHH CS
                xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         ADK  1 llGaPgaGKGtqaeklvkkyglahlstGdl 30
                + G+ g+GK t+a++l+ ++gl+ l   d+
  EEA20356.1 62 VTGPAGSGKTTVAKNLQAEMGLPFLEGDDF 91
                579*****************9998876665 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.088
                 EEEEE--HHHHHHHHHT.........................................GSHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxx.........................................xxxxxxxxxxxxx RF
         ADK 106 vleldvpeevlveRltg.........................................DneetvkkRlety 135
                 +++l+++e++l++R+ g                                         + +e vkk+l++y
  EEA20356.1 168 FIYLKADEKTLMDRVNGrashymkgnmvhsqfealedpsdevdvlavdvsvppdvvqrNVSEVVKKKLAEY 238
                 68999999999**9999999999999999999999999999999999999999888888889999999988 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00021      0.11       6      22 ..      61      77 ..      57     117 .. 0.85
   2 ?   -0.9   0.0         2   1.1e+03     137     176 ..     179     218 ..     162     234 .. 0.62

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00021
      AAA_24  6 liyGpsgiGKTtlakel 22
                +++Gp+g+GKTt+ak+l
  EEA20356.1 61 IVTGPAGSGKTTVAKNL 77
                579************99 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 2
      AAA_24 137 edpegeakytrlepklgkktanelkeevDlvlranlkred 176
                  d+  + + ++++ ++    +++l+  +D+v  + ++ ++
  EEA20356.1 179 MDRVNGRASHYMKGNMVHSQFEALEDPSDEVDVLAVDVSV 218
                 3333333667888888888888888888888777776555 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   0.00017     0.092       2      26 ..      61      85 ..      59     109 .. 0.75

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 0.00017
  RNA_helicase  2 wlyGpsgeGKStlakeLakallkkl 26
                  +++Gp+g GK+t+ak+L +++   +
    EEA20356.1 61 IVTGPAGSGKTTVAKNLQAEMGLPF 85
                  689*************999987444 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   0.00016     0.089      30      59 ..      53      83 ..      43      97 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00016
      RuvB_N 30 eealdhv.llyGpPGlGkttlakiiakelgv 59
                +++l h+ +++Gp G Gktt+ak + +e+g 
  EEA20356.1 53 DSSLQHIwIVTGPAGSGKTTVAKNLQAEMGL 83
                56889984578*****************996 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   0.00015     0.083      22      44 ..      57      79 ..      53     101 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00015
  Mg_chelatase 22 gHnlllvGppGsGKtmlakrlps 44
                  +H  +++Gp+GsGKt +ak l++
    EEA20356.1 57 QHIWIVTGPAGSGKTTVAKNLQA 79
                  688899*************9986 PP

>> CoaE  Dephospho-CoA kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   0.00022      0.12       5      32 ..      62      90 ..      59      99 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00022
                EEESTTSSHHHHHHHHHH.TT-EEEEHHH CS
        CoaE  5 ltGgiasGKstvanlfad.lgvpivDaDl 32
                +tG  +sGK+tva+ +++ +g+p +  D 
  EEA20356.1 62 VTGPAGSGKTTVAKNLQAeMGLPFLEGDD 90
                69**************999****999985 PP

>> Thermopsin  Thermopsin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   0.00022      0.12     193     245 ..      44      96 ..      22     101 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00022
  Thermopsin 193 lvngssltpsgllyDaeLvlgGpgngekttfnslnatlsLyYlngtnyqpvkn 245
                 +   ++++p+ +l    +v g  g+g++t+ ++l+a++ L +l+g +++p++n
  EEA20356.1  44 YMRNHNMNPDSSLQHIWIVTGPAGSGKTTVAKNLQAEMGLPFLEGDDFHPLSN 96 
                 55667888999999999999999*************************99876 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.1    0.0006      0.33       3      20 ..      60      77 ..      58      83 .. 0.85
   2 ?   -1.1   0.0       2.3   1.2e+03      50      88 ..     175     214 ..     165     217 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.0006
                EEEEESTTCCHHHHHHHH CS
        cobW  3 tvltGflGsGKTtLlnhl 20
                 ++tG+ GsGKTt+ ++l
  EEA20356.1 60 WIVTGPAGSGKTTVAKNL 77
                69***********98876 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 2.3
                 CT.EEEETTTTECCHCTT-HH.HHHHHHHHHHTT-SEEEE CS
        cobW  50 gveivelenGciCctlredll.kelealeereerldvili 88 
                 ++ +++  nG   + ++ +++  ++eale+ ++++dv+ +
  EEA20356.1 175 EKTLMDRVNGRASHYMKGNMVhSQFEALEDPSDEVDVLAV 214
                 4556666789999997777652578999999999999876 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   0.00033      0.18       3      34 ..      49      80 ..      47     101 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00033
                EEEEEEETTSEEEEEESTTSSHHHHHHHHTTS CS
                xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  3 nvslklkegekvaivGenGaGKStLlkllagl 34
                n++ + +  +++ ++G+ G+GK+t++k l  +
  EEA20356.1 49 NMNPDSSLQHIWIVTGPAGSGKTTVAKNLQAE 80
                5666667788999*************998765 PP

>> APS_kinase  Adenylylsulphate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   0.00029      0.16       5      26 ..      59      81 ..      56     122 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00029
                EE.EESSTTSSHHHHHHHHHHHH CS
  APS_kinase  5 vw.ltGlsgsGKstianalekkL 26
                +w +tG +gsGK+t+a++l+ ++
  EEA20356.1 59 IWiVTGPAGSGKTTVAKNLQAEM 81
                5526**************99764 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00036       0.2      23      38 ..      56      73 ..      43      79 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00036
      AAA_29 23 g..atlltGpsGsGKSTl 38
                   + ++tGp GsGK+T+
  EEA20356.1 56 LqhIWIVTGPAGSGKTTV 73
                334789***********7 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   0.00048      0.26      10      31 ..      57      78 ..      51      83 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00048
      AAA_19 10 ekvllvtaGpGtGKTrvlkhiv 31
                +++ +vt+++G+GKT+v k   
  EEA20356.1 57 QHIWIVTGPAGSGKTTVAKNLQ 78
                56789***********988765 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00046      0.25      32      64 ..      56      86 ..      44     101 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00046
      AAA_25 32 agelallaGapgtGKttlaldlalavatGkpwl 64
                ++++ +++G+ g+GKtt+a +l +++    p+l
  EEA20356.1 56 LQHIWIVTGPAGSGKTTVAKNLQAEMG--LPFL 86
                567789*************99988873..4554 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   0.00043      0.24       3      21 ..      61      79 ..      59      84 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00043
                EEE--TTSSHHHHHHHHHH CS
    NTPase_1  3 fiTGppGvGKtTlvkkvle 21
                ++TGp G+GKtT+ k++  
  EEA20356.1 61 IVTGPAGSGKTTVAKNLQA 79
                79***********998765 PP

>> PRK  Phosphoribulokinase / Uridine kinase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00035      0.19       4      44 ..      62      97 ..      59     109 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00035
         PRK  4 vagsSGaGkttvarklekifgrekvkaaeiegdsflrldra 44
                v+g+ G+Gkttva++l+  +g   ++    egd f+ l + 
  EEA20356.1 62 VTGPAGSGKTTVAKNLQAEMG---LP--FLEGDDFHPLSNK 97
                8****************9998...44..4557777766655 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00039      0.21      18      41 ..      56      78 ..      46      83 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00039
                SCSEEEEEEESTTSSHHHHHHHHC CS
      NB-ARC 18 lqslvvalvGmgGvGKttlakqil 41
                lq  +  + G +G+GKtt+ak+  
  EEA20356.1 56 LQ-HIWIVTGPAGSGKTTVAKNLQ 78
                45.455689***********9875 PP

>> PhoH  PhoH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0    0.0006      0.33      19      39 ..      57      77 ..      41      85 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.0006
                -SEEEEE--TTSSTTHHHHHH CS
        PhoH 19 ndivfaiGpaGtGKtylaval 39
                ++i +++GpaG+GKt +a  l
  EEA20356.1 57 QHIWIVTGPAGSGKTTVAKNL 77
                46899**********999765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (239 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       459  (0.025601); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                       104  (0.00580066); expected 17.9 (0.001)
Passed Fwd filter:                        33  (0.00184059); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              33  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 1602.59
//
Query:       EEA20357.1  [L=365]
Description: Vacuolar protein sorting-associated protein 26, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
   5.4e-130  432.3   0.2   6.5e-130  432.1   0.2    1.1  1  Vps26       Vacuolar protein sorting-associated protein 26
    0.00016   21.7   0.1       0.82    9.7   0.0    3.1  3  Arrestin_N  Arrestin (or S-antigen), N-terminal domain


Domain annotation for each model (and alignments):
>> Vps26  Vacuolar protein sorting-associated protein 26
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  432.1   0.2  7.2e-134  6.5e-130       1     274 [.       6     279 ..       6     280 .. 0.99

  Alignments for each domain:
  == domain 1  score: 432.1 bits;  conditional E-value: 7.2e-134
                 TTTSEEEEEEETTTTTS-EEEEE-GGG-EEEEEEE-TT--EEEEEEEEESST--EEESEEEEEEEEEEEETTTGGGEEEEEEEEEEEE-SEEESS-EEE CS
       Vps26   1 fkttidieikldneeerktvdvktekgkkeklkvyedgeslsGvvtirlkdskkvehqGikveliGqiellydkgnsvdfislvkdlakpGelqesksf 99 
                 f t++di+++l++++er+tvdvk +kg+ ek+++y dges++G vt+r kd+k++eh+Gikv++iG+ie+++d+gn+++f+slv++la pGelq+ ++f
  EEA20357.1   6 FSTPVDIDVVLEDSDERQTVDVKLDKGRREKAPLYMDGESVKGAVTVRPKDGKRLEHTGIKVQFIGSIEMFFDRGNHYEFLSLVQELAAPGELQHPQTF 104
                 789************************************************************************************************ PP

                 EEEETS----S--EE-SSEEEEEEEEEEEE-SSS-EEEEEEEEE---B---S----EEEEEEETTTEEEEEEES-SEEETT-EEEEEEEEEEE-S-EEE CS
       Vps26 100 pfefkklekryesYkGknvklrYvlrvtvvRklkditkekdlivhefttaPevnksvklevGiedclhiefeyskskyhLkdvivGkiyfllvrikiks 198
                 pf+fk++ek+yesY+G nvklrY++rvtv+R++ d+++ekdl+v+++ + Pe+n+++k++vGiedclhiefeysks+yhLkdvivG+iyfllvr+kik+
  EEA20357.1 105 PFNFKNVEKQYESYNGINVKLRYFVRVTVSRRMADVIREKDLWVYSYRMPPETNSPIKMDVGIEDCLHIEFEYSKSQYHLKDVIVGRIYFLLVRLKIKH 203
                 *************************************************************************************************** PP

                 EEEEEEEEEEESSTTCEEEEEEEEEEEEEEES---TT-EEEEEEEGGGG-----EEEETTTEEEEEEEEEEEEETT CS
       Vps26 199 melslikrestGlaenvakdsetiakyeimDGasvrgesiPirlflsgydltPtlrdvnkkfsvkyylnlvlvded 274
                 mels+i+re+tG+a+n++++set++++eimDG++ rge+iPirlfl g+dl+Pt+rdvnkk+s +yyl+lvl+ded
  EEA20357.1 204 MELSIIRRETTGAAPNQYNESETLVRFEIMDGSPSRGETIPIRLFLGGFDLSPTFRDVNKKYSTRYYLSLVLIDED 279
                 **************************************************************************98 PP

>> Arrestin_N  Arrestin (or S-antigen), N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   0.0   9.2e-05      0.82       4      44 ..      28      74 ..      25      82 .. 0.75
   2 !    7.4   0.0   0.00047       4.2      93     127 ..     103     137 ..      89     149 .. 0.89
   3 ?    0.5   0.0     0.063   5.7e+02       2      26 ..     172     196 ..     171     240 .. 0.71

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 9.2e-05
                EES....-SEEEEETT--EEEEEEE-CCCCTT...CEEEEEEEEEEE CS
  Arrestin_N  4 eld....krdevyhpgetvdGkvlleteelkka..rkvkielsgkar 44
                +ld    ++ + y  ge+v+G v++++++ k++  +++k+++ g ++
  EEA20357.1 28 KLDkgrrEKAPLYMDGESVKGAVTVRPKDGKRLehTGIKVQFIGSIE 74
                55544445678999***********9998776522678888888765 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.00047
                 EEEEEE---TTS--SECSGEEEEEEEEEEEEECCC CS
  Arrestin_N  93 afpFsfelPknlpsSfeGkaggvrYevkvtldrpw 127
                 +fpF+f+  ++   S +G   + rY+v+vt+ r  
  EEA20357.1 103 TFPFNFKNVEKQYESYNGINVKLRYFVRVTVSRRM 137
                 8******************************9875 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.063
                 EEEES-SEEEEETT--EEEEEEE-C CS
  Arrestin_N   2 tieldkrdevyhpgetvdGkvllet 26 
                 +ie++ ++  yh  + + G++ +  
  EEA20357.1 172 HIEFEYSKSQYHLKDVIVGRIYFLL 196
                 6899999999*********997643 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (365 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       701  (0.0390987); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 2579.46
//
Query:       EEA20358.1  [L=1712]
Description: endosomal peripheral membrane protein (Mon2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-40  138.6   4.9    1.7e-40  138.6   4.9    3.1  3  DCB       Dimerisation and cyclophilin-binding domain of Mon2
      2e-38  131.8  16.2    1.6e-37  128.8   4.3    4.2  4  Sec7_N    Guanine nucleotide exchange factor in Golgi transpo
    3.7e-22   78.3   5.2    6.3e-22   77.6   0.8    3.1  3  Mon2_C    C-terminal region of Mon2 protein
    7.5e-05   22.5   0.1       0.35   10.8   0.0    5.5  5  DUF1981   Domain of unknown function (DUF1981)
    0.00055   20.5   2.4        1.9    9.1   0.1    5.0  4  Ipi1_N    Rix1 complex component involved in 60S ribosome mat


Domain annotation for each model (and alignments):
>> DCB  Dimerisation and cyclophilin-binding domain of Mon2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.6   4.9   4.6e-44   1.7e-40       8     178 .]       4     175 ..       1     175 [. 0.97
   2 ?   -0.1   0.3      0.18   6.3e+02      97     133 ..     234     269 ..     198     285 .. 0.71
   3 ?   -4.1   0.0       2.9     1e+04      70     110 ..     948     990 ..     946    1002 .. 0.63

  Alignments for each domain:
  == domain 1  score: 138.6 bits;  conditional E-value: 4.6e-44
         DCB   8 ealqsdlkalsseskrkhskvkeasekgilkLktikssseee.eqslaeaseeilkPlllacetknpkivqiaLgslqrLisheviseeaiskiietlw 105
                 + lq++l +l +eskrk+s++++a+e+++ +Lk + s+se + + +l++  +++++P++lac+t++ k+ +i + +lqrL + ++is +++++ +++l 
  EEA20358.1   4 QILQTELSNLIQESKRKYSDLRNAAEQSLNNLKALPSTSEAQiTADLIRR-PHFVTPFILACQTRQSKLASIGVVCLQRLATSHAISPSRLNDTLSALG 101
                 579************************************87789999999.************************************************ PP

         DCB 106 kllelgveielkvLqtllllvttss.vvhgdtlakalvlCfrLhfskdnvvqntAaAtlrQlvsvvFeRvvaed 178
                 +++ l+++++lk+Lqtl+ l+  +s ++ g++la++l +C  L+ sk  +v+ntAaAtl+Qlvs  Fe+v  ed
  EEA20358.1 102 DITGLSQDVQLKILQTLPALLHNYSdELSGELLAHVLEVCATLQASKVAAVSNTAAATLQQLVSSAFEKVLVED 175
                 **********************************************************************9997 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.18
         DCB  97 iskiietlwkllelgveielkvLqtllllvttssvvh 133
                 i++i+   +kl+ ++ e ++++Lqt ll +t ++  +
  EEA20358.1 234 IESILINNIKLFRNHPE-QMQLLQTRLLPLTVKHLSE 269
                 44555555788888999.9999999988888777555 PP

  == domain 3  score: -4.1 bits;  conditional E-value: 2.9
         DCB  70 tknpkivqiaLgslqrLishevis...eeaiskiietlwkllel 110
                  ++p++v  a +slq Li+ + ++    + + +++++l   ++ 
  EEA20358.1 948 ARSPRLVRAAYSSLQ-LIASDFLTllpPSCLLELVDSLSFFASQ 990
                 578999999999998.5555544422255566666666555555 PP

>> Sec7_N  Guanine nucleotide exchange factor in Golgi transport N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.1         2   7.1e+03      89     115 ..     118     144 ..     107     173 .. 0.48
   2 !  128.8   4.3   4.5e-41   1.6e-37       2     158 .]     198     352 ..     197     352 .. 0.97
   3 ?    0.9   0.1      0.11   3.9e+02      23      61 ..     880     918 ..     857    1015 .. 0.69
   4 !    8.0   0.0   0.00069       2.5      73     139 ..    1225    1300 ..    1209    1305 .. 0.77

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 2
      Sec7_N  89 vllLlkkfrseLktEievflsllilil 115
                 +  Ll+++++eL  E+ + + ++   l
  EEA20358.1 118 LPALLHNYSDELSGELLAHVLEVCATL 144
                 334444444444444433333333333 PP

  == domain 2  score: 128.8 bits;  conditional E-value: 4.5e-41
      Sec7_N   2 akDaflvfrdLcklinsakskpkflslaersktfsLeLlesvlsnhgdvfrkhpellqllkqklcplLlknlsespsfpvferslrivllLlkkfrseL 100
                 a+D +++++dLc+ ++ ++ k +fl+++++   f LeL+es+l n+ ++fr+hpe++qll+++l+pl +k lse+++f  ++r++ri+l+Ll++f s+L
  EEA20358.1 198 AHDTLQILSDLCRAVE-GE-KLEFLHIKVLPTNFILELIESILINNIKLFRNHPEQMQLLQTRLLPLTVKHLSERHNFAHTLRVARILLVLLRNFMSSL 294
                 79************99.88.8****************************************************************************** PP

      Sec7_N 101 ktEievflsllililles.dsslwqrvlaLeilrrlcsdpqllvelylnYDcdeeaknv 158
                 ++E+e+ l lli+ l e+  s+ w+rvl++e++r+l s+p l++ +y+ +D  e +k++
  EEA20358.1 295 QDECEMALGLLIHLL-EPeASPEWKRVLCMEVFRSLHSEPSLIRLIYTLFDKAEGRKDI 352
                 ***************.8868888******************************999876 PP

  == domain 3  score: 0.9 bits;  conditional E-value: 0.11
      Sec7_N  23 pkflslaersktfsLeLlesvlsnhgdvfrkhpellqll 61 
                  k++s++     ++L+ l  +l+++g+ f++  +l++ l
  EEA20358.1 880 DKLTSVDAEAHGYALDTLRVMLEQYGETFTSGWDLIFEL 918
                 554588888888899999999999999998555555444 PP

  == domain 4  score: 8.0 bits;  conditional E-value: 0.00069
      Sec7_N   73 lsespsfpvferslrivllLlkkfrseLktEiev.flsllililles.........dsslwqrvlaLeilrrlcsdp 139 
                  l e+p+   +   +r++ ++++ +r+eL +E+ + +l+++   + +s         d ++  ++l+L +++ lc d 
  EEA20358.1 1225 L-EEPNQDALIAYFRLFQQIYRLYRDELSQELVAqVLHHVRTAIWNSvvsrysvdiDHQSTLQELVLDCIKTLCLDR 1300
                  5.67788888899******************64414555555555444444444557778**************875 PP

>> Mon2_C  C-terminal region of Mon2 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0     0.057   2.1e+02     198     219 ..     665     686 ..     653     695 .. 0.84
   2 !   77.6   0.8   1.8e-25   6.3e-22       2     236 ..     967    1196 ..     966    1205 .. 0.89
   3 ?   -0.6   0.0     0.074   2.7e+02     466     586 ..    1333    1461 ..    1328    1472 .. 0.74

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.057
      Mon2_C 198 rawdlllefiqsaalsknnevs 219
                  aw++lle +q+a l  n+  +
  EEA20358.1 665 TAWSILLETLQNADLVINASAT 686
                 69*************9997665 PP

  == domain 2  score: 77.6 bits;  conditional E-value: 1.8e-25
      Mon2_C    2 dfltvmpwrclqlvvdvaakfglqtqelnisltaigllwnisdyffq.....keeklqskqleekavlpefpatvklpqfdklwlclyaklgelcvd 93  
                  dflt +p  cl   vd  + f +q+q++nislt+  ++wn+sd++         e+ +++ + + ++      +        lwl l  ++ +l  d
  EEA20358.1  967 DFLTLLPPSCLLELVDSLSFFASQNQDFNISLTTTTFFWNVSDFLQSqvgtfSIEESMDTSISDESLATLTDDADISTSRGALWLLLLLRIVDLTTD 1063
                  9*******************************************98767777677888888888888876666566677899*************** PP

      Mon2_C   94 lrpavrksagqtlfstisahgsllnpstwqalvwkvlfnlldrvrelsssadkekveasgnilihhsrdtaekqwaetqvltlagvarvfntkrell 190 
                   r  +r sa  tl+  + a+g  l p +w+  + +vlf ++  v++ +  +     e+s +         a k+w et v+ + g + ++ t  + +
  EEA20358.1 1064 ARSGIRNSAIHTLLRILDAYGPQLTPKAWHLCLNRVLFVMMVDVQNKALQT-----ESSAD-----RGSDAVKEWIETSVVLIKGSTDLIATFFDTI 1150
                  ****************************************99998776543.....33332.....234688********************99998 PP

      Mon2_C  191 qmlgdferawdlllefiqsaalsknnevslaalkslqeilyivstv 236 
                       f  +w+ lle  q+     n  +  a + s  +i++++ ++
  EEA20358.1 1151 IQDPRFVDSWKRLLECFQALVRIDNYGIKEAIFASTCDIIKHAKPT 1196
                  88999**************99999999**9******9999998876 PP

  == domain 3  score: -0.6 bits;  conditional E-value: 0.074
      Mon2_C  466 yvpfaekslevvvdlyqktateesvvqeqilhdivkalrvplalkykc....lsestwklavssllkvlsiglkvar.....aksqkfdslwdelad 553 
                  yv f++ ++++      +   +  +  +  l   ++ l  p++ ky+       +  w+ a  s +k++++ ++        ++  ++ s+w  + d
  EEA20358.1 1333 YVAFSKSAIDLLSWYIAEHGIKADIFSDGTLTTALQHLAHPITRKYEWggkdREQLIWQKATISAIKIIRVTVPYVEskyaaSEKSRIISFWSTVVD 1429
                  888998899988887788888889999999999*************86111144568************9999865545632445578899999998 PP

      Mon2_C  554 tledflftksvctiedlsl..eeivldesidvevv 586 
                      ++ ++     +dl++    i  de  d+e  
  EEA20358.1 1430 ITRGIISAND---YDDLGIpaSRIASDEEFDIEAF 1461
                  8776665444...4777763345777777777765 PP

>> DUF1981  Domain of unknown function (DUF1981)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       2.3   8.2e+03      33      45 ..     447     459 ..     443     463 .. 0.80
   2 ?   -0.2   0.0      0.25   8.9e+02      45      64 ..     525     544 ..     522     554 .. 0.84
   3 !   10.8   0.0   9.7e-05      0.35      35      70 ..     891     926 ..     881     943 .. 0.82
   4 ?   -0.1   0.0      0.23   8.2e+02      21      53 ..    1147    1179 ..    1142    1192 .. 0.77
   5 ?    2.2   0.0     0.047   1.7e+02      29      47 ..    1281    1299 ..    1274    1303 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 2.3
     DUF1981  33 irelvlecveqli 45 
                 i+ lvl+c++ l 
  EEA20358.1 447 IYSLVLNCLSALA 459
                 8899****99876 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.25
     DUF1981  45 iqsraeniksGWktifgvlt 64 
                 i+s+a  i+s W++i++ ++
  EEA20358.1 525 ITSSAGIIESCWPVILTTCS 544
                 6678889*********9876 PP

  == domain 3  score: 10.8 bits;  conditional E-value: 9.7e-05
     DUF1981  35 elvlecveqliqsraeniksGWktifgvltaaakee 70 
                  + l+ ++ ++++ +e+ +sGW  if++++ + ++ 
  EEA20358.1 891 GYALDTLRVMLEQYGETFTSGWDLIFELISSVFEKP 926
                 56789999*********************9987654 PP

  == domain 4  score: -0.1 bits;  conditional E-value: 0.23
     DUF1981   21 Feeimsnnssaeirelvlecveqliqsraenik 53  
                  F +i+++ + ++  + +lec++ l++     ik
  EEA20358.1 1147 FDTIIQDPRFVDSWKRLLECFQALVRIDNYGIK 1179
                  677888888888888888888888877666655 PP

  == domain 5  score: 2.2 bits;  conditional E-value: 0.047
     DUF1981   29 ssaeirelvlecveqliqs 47  
                  ++++++elvl+c++ l+  
  EEA20358.1 1281 HQSTLQELVLDCIKTLCLD 1299
                  46679*********99865 PP

>> Ipi1_N  Rix1 complex component involved in 60S ribosome maturation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.1     0.035   1.3e+02      18      71 ..     103     155 ..      96     175 .. 0.66
   2 ?    3.2   0.0     0.038   1.4e+02      18      73 ..     882     936 ..     878     961 .. 0.69
   3 !    9.1   0.1   0.00053       1.9      22      74 ..    1065    1117 ..    1053    1136 .. 0.77
   4 ?   -3.0   0.0       3.2   1.1e+04      45      61 ..    1156    1172 ..    1139    1179 .. 0.71

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.035
      Ipi1_N  18 mTHispdIredslkfLdllLevapeelvssa.wvktLnnflallgwskeksskgs 71 
                 +T +s+d++   l++L +lL+ +++e +s +  +++L+ ++a l +sk +  +++
  EEA20358.1 103 ITGLSQDVQLKILQTLPALLHNYSDE-LSGElLAHVLE-VCATLQASKVAAVSNT 155
                 5889******************9999.44442444444.4555555443333333 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.038
      Ipi1_N  18 mTHispdIredslkfLdllLevapeelvssawvktLnnflallgwskeksskgsts 73 
                 +T+++++    +l++L ++Le ++e   +s w  + + + +++ + ++++s+ s+ 
  EEA20358.1 882 LTSVDAEAHGYALDTLRVMLEQYGET-FTSGWDLIFELISSVFEKPETEKSETSSL 936
                 57888888889*************99.66668888888888888843222222222 PP

  == domain 3  score: 9.1 bits;  conditional E-value: 0.00053
      Ipi1_N   22 spdIredslkfLdllLevapeelvssawvktLnnflallgwskeksskgstsa 74  
                   + Ir++++++L  +L++++ +l  +aw  +Ln +l ++ ++ +++  +++s+
  EEA20358.1 1065 RSGIRNSAIHTLLRILDAYGPQLTPKAWHLCLNRVLFVMMVDVQNKALQTESS 1117
                  578*******************99999*******9999999543333333322 PP

  == domain 4  score: -3.0 bits;  conditional E-value: 3.2
      Ipi1_N   45 vssawvktLnnflallg 61  
                    ++w ++L++f al +
  EEA20358.1 1156 FVDSWKRLLECFQALVR 1172
                  345699******98865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1712 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       785  (0.0437838); expected 358.6 (0.02)
Passed bias filter:                      589  (0.0328518); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 1.02u 0.28s 00:00:01.30 Elapsed: 00:00:00.47
# Mc/sec: 10885.00
//
Query:       EEA20359.1  [L=138]
Description: ubiquitin conjugating enzyme (MmsB), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.2e-20   71.5   0.0    5.4e-20   71.5   0.0    1.0  1  UQ_con    Ubiquitin-conjugating enzyme
  ------ inclusion threshold ------
      0.015   15.6   0.0      0.015   15.6   0.0    1.2  1  RWD       RWD domain


Domain annotation for each model (and alignments):
>> UQ_con  Ubiquitin-conjugating enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.5   0.0     6e-24   5.4e-20      21     114 ..      30     127 ..       9     137 .. 0.85

  Alignments for each domain:
  == domain 1  score: 71.5 bits;  conditional E-value: 6e-24
                 EEE..TTEECEEEEEEEB.TTSTTTTEEEEEEEE--TTTTTS--EEEESST-SCTTBE.TTSBB-CGGGSTTT.--TTSHHHHHHHHHHHHHHS--TT CS
      UQ_con  21 lvd..denlfewkvlikgpedtpYeggvFklelefpedYPlkpPkvkfvtkifHPnvd.ksGevcldiLkeek.WspaltlesvllsiqsLlaepnpe 114
                 l d  d  +++w+++i gp++++ e+ ++ ++++  ++YP +pP+++fv+ki  P vd ++G+v l+ L +   W++ +t+e++ll++  ++a p+ +
  EEA20359.1  30 LADgdDITMTNWNGTILGPPHSVHENRIYSVNIQCGPEYPDSPPTLHFVSKINLPCVDsRTGKVDLSTLPTLAtWKRDYTMETILLELRRFMALPQHK 127
                 4443246899***********************************************************96445******************999654 PP

>> RWD  RWD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.6   0.0   1.7e-06     0.015      47      81 ..      50      84 ..       5     122 .. 0.73

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 1.7e-06
                ..TT-CEEEEEEEEE-SSTTSS--EEEEEECCSS- CS
                xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         RWD 47 feekkkpslkleiklpeeYPeeaPiislsstenlp 81
                ++  ++  ++++i++ +eYP+++P +++ s+ nlp
  EEA20359.1 50 HSVHENRIYSVNIQCGPEYPDSPPTLHFVSKINLP 84
                55666777899****************99998666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (138 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       184  (0.0102627); expected 358.6 (0.02)
Passed bias filter:                      178  (0.00992805); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.37u 0.27s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 1012.71
//
Query:       EEA20360.1  [L=309]
Description: DNA repair protein (Rad1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.2e-13   50.0   0.0    5.4e-13   48.8   0.0    1.7  1  Complex1_LYR    Complex 1 protein (LYR family)
  ------ inclusion threshold ------
      0.018   15.8   0.0       0.05   14.4   0.0    1.8  1  Complex1_LYR_2  Complex1_LYR-like


Domain annotation for each model (and alignments):
>> Complex1_LYR  Complex 1 protein (LYR family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.8   0.0   6.1e-17   5.4e-13       3      58 ..      17      73 ..      15      74 .. 0.96

  Alignments for each domain:
  == domain 1  score: 48.8 bits;  conditional E-value: 6.1e-17
  Complex1_LYR  3 vLsLYRalLRearkfpdyn.treyfrrriRdeFrknkhvtDpekieellkkgreeLe 58
                  + +LYRalLR+++ +p+++   e + r +R eF +n+ +++p k  + l++g+e+L+
    EEA20360.1 17 CFALYRALLRQCSELPSTTgGNETLSRIVRREFNRNRTLKSPTKTIHSLQAGYEALD 73
                  779****************9999********************************98 PP

>> Complex1_LYR_2  Complex1_LYR-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   5.6e-06      0.05       3      60 ..      19      78 ..      17     122 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 5.6e-06
  Complex1_LYR_2  3 sLYrrllrelrelppelr..slgdayvraefrrhkhlknpeeialflknqreYaellery 60
                    +LYr+llr+  elp +    + + + vr ef+r++ lk p + +  l++  e +++++  
      EEA20360.1 19 ALYRALLRQCSELPSTTGgnETLSRIVRREFNRNRTLKSPTKTIHSLQAGYEALDIMHAA 78
                    79********9875554456******************9999999999988888888766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       566  (0.031569); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.30s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2186.65
//
Query:       EEA20361.1  [L=232]
Description: RWD domain protein (Gir2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.9e-25   87.2   2.3    8.9e-25   87.2   2.3    1.7  2  RWD            RWD domain
  ------ inclusion threshold ------
        0.1   13.1  18.8        0.3   11.6  18.1    2.2  1  DFRP_C         DRG Family Regulatory Proteins, Tma46
       0.23   10.6   1.4       0.27   10.4   1.4    1.1  1  Zip            ZIP Zinc transporter
        1.1    8.8   4.1       0.65    9.5   1.3    1.8  2  Peptidase_S15  X-Pro dipeptidyl-peptidase (S15 family)
        2.4    6.8   5.5          3    6.5   5.5    1.1  1  Presenilin     Presenilin
        3.1    8.1  11.0          7    6.9  11.0    1.6  1  DRY_EERY       Alternative splicing regulator


Domain annotation for each model (and alignments):
>> RWD  RWD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.2   2.3     3e-28   8.9e-25       1     115 [.       4     116 ..       4     117 .. 0.92
   2 ?   -2.0   0.2       1.4   4.1e+03      33      49 ..     167     183 ..     137     195 .. 0.61

  Alignments for each domain:
  == domain 1  score: 87.2 bits;  conditional E-value: 3e-28
                 HHHHHHHHHHHHHSTTTCCCCHT--EE--S-EEEEEEECECCCC....TT-CEEEEEEEEE-SSTTSS--EEEEEECCSS-.......HHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxx RF
         RWD   1 eeqeqEleaLesIypdefevienenysikleikikldededeedsefeekkkpslkleiklpeeYPeeaPiislsstenlp.......keqvksleekl 92 
                 eeq +E e+L+sI+p+e+++i+++ y+    i+i+ld+dedee+     +k p+l l++++pe YP++aP +++ ++ n         +e++++l+e +
  EEA20361.1   4 EEQVEEREVLDSIFPEEITDISDTSYR----ITITLDLDEDEEN-----EKAPTLLLQVSYPEAYPDVAPDLEILTPPNSAkhtrfdlQEDKAQLMEAI 93 
                 79*************************....9999999999975.....89***************************3334556667899999***** PP

                 HHHHHHTTTS--CHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxx RF
         RWD  93 eelaeenlgepvifalidwlken 115
                 +  +eenlg+++if+l++ lke 
  EEA20361.1  94 QPSIEENLGMAMIFTLVSTLKEA 116
                 *********************96 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.4
                 EEEEEECECCCC....T CS
                 xxxxxxxxxxxxxxxxx RF
         RWD  33 kikldededeedsefee 49 
                 + + +e+ ++e++e+ee
  EEA20361.1 167 EMEEEEQREREEKEAEE 183
                 33333344444444444 PP

>> DFRP_C  DRG Family Regulatory Proteins, Tma46
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6  18.1    0.0001       0.3      13      77 ..     142     219 ..     134     229 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.0001
      DFRP_C  13 akLdk.klTpvtletFakWKkkrlekkeaeeekeekkkkke............glsGrelfefnpelaedddeeeeee 77 
                 ++  k + T v+ e F +W++k  ++ e+ee++e+++k++e            +l+Gr+l e     + d+dee e+e
  EEA20361.1 142 EENRKfQGTLVNKERFLEWREKFRKEMEEEEQREREEKEAEekkkkpsareeqKLTGRQLWERGLAGKGDYDEEGEDE 219
                 3334445699**********999999999999888888888888999**************85555555555555443 PP

>> Zip  ZIP Zinc transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   1.4     9e-05      0.27      91     171 ..     112     196 ..      72     228 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 9e-05
         Zip  91 lveklltmivek....ksshkektpkkasssssesaakksvsndkveeseekedhvaeadtdadskeelrngkqeksesekeqas 171
                 ++ ++++ ++ +    ++++ e +  +a+++++++  +  v+++ + e++ek++++ e++++++ +e+++++k++k++ ++eq+ 
  EEA20361.1 112 TLKEAAETLIMErvasERQAREREIAEAEEEENRKFQGTLVNKERFLEWREKFRKEMEEEEQREREEKEAEEKKKKPSAREEQKL 196
                 444433333333465444555555556666666666777799999*******************9*****999999999999865 PP

>> Peptidase_S15  X-Pro dipeptidyl-peptidase (S15 family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.1      0.29   8.6e+02      13      31 ..      39      57 ..      29      77 .. 0.79
   2 ?    9.5   1.3   0.00022      0.65     143     230 ..     146     231 ..     126     232 .] 0.67

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.29
                   ..TTSSSEEEEEEEESS-C CS
  Peptidase_S15 13 etkskeklPvlltrtPYgk 31
                   e++++ek+P+ll + +Y +
     EEA20361.1 39 EDEENEKAPTLLLQVSYPE 57
                   678999*******999974 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00022
                    SECTTEEBCCHHHHHHH.HHCCCCHHTSSS-STTHHHHHHHHHHCHCCCCCCTTHHH....THHHHCCCC--SSSHHHHTT-HHHHHCT--S- CS
  Peptidase_S15 143 yregGlvrapgglswed.ldllaealtsrradegdalkaaaryeaasdellaeldrq....tpveselletgdydafWkdrnlsedadkvkap 230
                     ++g lv ++++l w +     +e+ ++r+++e++a +++++  +a++e  +    +    + +e+ l+ +gdyd+  +d  +se+++k++++
     EEA20361.1 146 KFQGTLVNKERFLEWREkFRKEMEEEEQREREEKEAEEKKKK-PSAREE--Q----KltgrQLWERGLAGKGDYDEEGEDELPSEAVEKLQIS 231
                    5889999999999*9430333444444444444433333332.222222..2....22243679********************999999876 PP

>> Presenilin  Presenilin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   5.5     0.001         3     214     298 ..     105     194 ..      88     216 .. 0.44

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.001
  Presenilin 214 LiYsatvvvlaaeek.....kaevaeseeeeeaekkkeeasesskeeeseeesseksaqsseseeeseeesseaessaeesseekesees 298
                 +i+    +  +a+e+      a++++++e+e ae+++ee+++ + +  ++e++ e +++ +++ ee+e++++e+++++e++++++++ee+
  EEA20361.1 105 MIFTLVSTLKEAAETlimerVASERQAREREIAEAEEEENRKFQGTLVNKERFLEWREKFRKEMEEEEQREREEKEAEEKKKKPSAREEQ 194
                 555444444433333332222233334444444444444444444444444444433333333333333333322222222222222222 PP

>> DRY_EERY  Alternative splicing regulator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9  11.0    0.0023         7      57     120 ..     128     195 ..     113     214 .. 0.58

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0023
    DRY_EERY  57 ekkarseeksseeeeeee.....elnyERYrdLiknefeevseeeelkqiaeeesfsaekkkeaekkkk 120
                 e++ar++e  + eeee++      +n+ER+++  ++ ++e++ eee ++ +e+e+ +++kk +a++++k
  EEA20361.1 128 ERQAREREIAEAEEEENRkfqgtLVNKERFLEWREKFRKEME-EEEQREREEKEAEEKKKKPSAREEQK 195
                 233333333333333333677779********9555555555.44444444444434444444444333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (232 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2316  (0.129176); expected 358.6 (0.02)
Passed bias filter:                      809  (0.0451224); expected 358.6 (0.02)
Passed Vit filter:                       127  (0.0070835); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.55u 0.32s 00:00:00.87 Elapsed: 00:00:00.43
# Mc/sec: 1615.70
//
Query:       EEA20362.1  [L=402]
Description: TPR domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.8e-12   47.4   0.9    3.8e-07   30.3   0.2    3.9  4  TPR_12        Tetratricopeptide repeat
    1.2e-11   44.9   4.1    3.8e-06   27.3   0.2    3.7  3  TPR_19        Tetratricopeptide repeat
    1.6e-07   31.0   2.6    0.00072   19.6   0.0    4.6  3  TPR_8         Tetratricopeptide repeat
    3.5e-07   29.8   3.2      0.007   16.4   0.0    5.2  5  TPR_2         Tetratricopeptide repeat
    1.3e-06   28.1   1.6    0.00082   18.8   0.0    2.7  2  TPR_MalT      MalT-like TPR region
    4.7e-06   27.1   1.5      0.087   13.5   0.3    4.4  3  TPR_16        Tetratricopeptide repeat
    1.7e-05   25.3   4.9        1.4    9.9   0.1    5.2  5  TPR_14        Tetratricopeptide repeat
    6.7e-05   22.5   0.1       0.12   12.2   0.0    3.9  3  TPR_1         Tetratricopeptide repeat
    7.1e-05   22.9   7.9      0.012   15.7   0.2    4.2  4  TPR_9         Tetratricopeptide repeat
    0.00051   20.2   0.3       0.98    9.7   0.0    3.4  3  ANAPC3        Anaphase-promoting complex, cyclosome, subunit 
     0.0017   18.0   0.2      0.012   15.3   0.0    2.6  3  TPR_11        TPR repeat
     0.0026   17.6   0.9        9.7    6.2   0.1    4.4  4  TPR_10        Tetratricopeptide repeat
     0.0081   16.5   0.3    1.1e+02    3.5   0.0    4.9  5  TPR_17        Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.017   13.9   0.3      0.051   12.4   0.1    1.7  2  Cas_Cas02710  CRISPR-associated protein (Cas_Cas02710)
      0.018   15.0   0.2        8.8    6.6   0.0    4.1  3  TPR_7         Tetratricopeptide repeat
      0.021   14.3   4.3       0.41   10.1   0.1    3.3  3  SHNi-TPR      SHNi-TPR
       0.24   12.1   4.6    1.3e+02    3.6   0.1    5.1  5  TPR_6         Tetratricopeptide repeat
        6.7    7.7   8.2         17    6.4   0.6    3.5  2  TPR_4         Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.3   0.2   3.9e-10   3.8e-07       8      76 ..      41     106 ..      34     107 .. 0.90
   2 ?   -2.2   0.0       5.2   5.1e+03      22      41 ..     145     161 ..     143     166 .. 0.76
   3 !   12.0   0.0   0.00019      0.19       6      37 ..     216     246 ..     212     252 .. 0.87
   4 ?   -0.3   0.1       1.3   1.3e+03      25      36 ..     325     336 ..     320     351 .. 0.69

  Alignments for each domain:
  == domain 1  score: 30.3 bits;  conditional E-value: 3.9e-10
      TPR_12   8 nlaavlrrlgrydeAlellekaleia.rrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                 + a++l++ g+ + Al l +++lei  +++  p++  t+ + +  +++y +lg+ ++A+e + +a+++++
  EEA20362.1  41 EKATILLQTGQAEAALPLAQRVLEISdEKS--PNN--TLLAINLVAEIYVELGEIDAARESFLHAVQLDP 106
                 789***********************5555..998..****************************99875 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 5.2
      TPR_12  22 AlellekaleiarrllGpdh 41 
                 Al++  ++le++    G d 
  EEA20362.1 145 ALRHIIQSLEQC---GGADT 161
                 899999999999...66665 PP

  == domain 3  score: 12.0 bits;  conditional E-value: 0.00019
      TPR_12   6 lnnlaavlrrlgrydeAlellekaleiarrll 37 
                 +  la+v   + r d+A++ l ++le+++ l+
  EEA20362.1 216 Q-TLASVRISQTRIDDAQAALSRSLELWQDLP 246
                 5.69************************9885 PP

  == domain 4  score: -0.3 bits;  conditional E-value: 1.3
      TPR_12  25 llekaleiarrl 36 
                 +l+++l ++++l
  EEA20362.1 325 WLKQSLKLYQKL 336
                 667777777766 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.2   3.9e-09   3.8e-06       1      52 [.      46     102 ..      46     110 .. 0.86
   2 !   14.2   0.2   4.7e-05     0.047      14      54 ..     201     241 ..     191     250 .. 0.86
   3 ?    2.7   0.0      0.19   1.9e+02       9      35 ..     273     299 ..     256     307 .. 0.67

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 3.9e-09
      TPR_19   1 llaegdyaeAlalleqalqe....dpknaearllL.AeallalgqldeAealLdalp 52 
                 ll+ g+ ++Al+l +++l+     +p+n  ++++L Ae++++lg++d+A++    + 
  EEA20362.1  46 LLQTGQAEAALPLAQRVLEIsdekSPNNTLLAINLvAEIYVELGEIDAARESFLHAV 102
                 7999**************555556*********999**************9876555 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 4.7e-05
      TPR_19  14 leqalqedpknaearllLAeallalgqldeAealLdalpee 54 
                  ++al  +p++++ +  LA + +++ ++d+A+a+L++ +e 
  EEA20362.1 201 ITEALLVAPDQPDCLQTLASVRISQTRIDDAQAALSRSLEL 241
                 4568889*****************************98876 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.19
      TPR_19   9 eAlalleqalqedpknaearllLAeal 35 
                 eAl  le+++ ed ++ ea++l   +l
  EEA20362.1 273 EALHVLERLILEDDESIEAWYLGGWCL 299
                 677777777777777777777555555 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   0.1     0.014        14       6      31 ..      41      66 ..      29      69 .. 0.92
   2 !   19.6   0.0   7.2e-07   0.00072       5      33 ..      79     107 ..      77     107 .. 0.92
   3 ?    1.4   0.0       0.5     5e+02       3      30 ..     214     241 ..     212     241 .. 0.89

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.014
                HHHHHHHHTT-HHHHHHHHHHHHHHH CS
       TPR_8  6 nlgsiylklgdyeeAkeyyekaleld 31
                 ++ i+l++g+ e+A    +++le++
  EEA20362.1 41 EKATILLQTGQAEAALPLAQRVLEIS 66
                6899*******************997 PP

  == domain 2  score: 19.6 bits;  conditional E-value: 7.2e-07
                 HHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   5 ynlgsiylklgdyeeAkeyyekaleldpd 33 
                 ++ + iy +lg++++A e++ +a++ldp+
  EEA20362.1  79 NLVAEIYVELGEIDAARESFLHAVQLDPE 107
                 56799**********************96 PP

  == domain 3  score: 1.4 bits;  conditional E-value: 0.5
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAkeyyekalel 30 
                  ++ l+s+ +++ +++ A++++ + lel
  EEA20362.1 214 CLQTLASVRISQTRIDDAQAALSRSLEL 241
                 567899999*************999987 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.0     0.019        19       4      31 ..      39      66 ..      36      68 .. 0.88
   2 !   16.4   0.0   7.1e-06     0.007       5      33 ..      79     107 ..      76     107 .. 0.91
   3 ?    3.5   0.0     0.094        93       2      30 ..     213     241 ..     212     241 .. 0.90
   4 ?   -2.0   0.0       5.6   5.5e+03      13      30 ..     267     284 ..     260     287 .. 0.71
   5 ?   -1.7   0.0       4.4   4.4e+03      16      26 ..     325     335 ..     322     340 .. 0.65

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.019
       TPR_2  4 lynlGlayyklgdyeeAleafekAleld 31
                l + + ++++ g+ e Al + +++le+ 
  EEA20362.1 39 LLEKATILLQTGQAEAALPLAQRVLEIS 66
                667899*******************986 PP

  == domain 2  score: 16.4 bits;  conditional E-value: 7.1e-06
       TPR_2   5 ynlGlayyklgdyeeAleafekAleldPn 33 
                 +  +++y +lg+ + A+e f  A++ldP+
  EEA20362.1  79 NLVAEIYVELGEIDAARESFLHAVQLDPE 107
                 56799***********************6 PP

  == domain 3  score: 3.5 bits;  conditional E-value: 0.094
       TPR_2   2 ealynlGlayyklgdyeeAleafekAlel 30 
                 ++l  l+ + + + + ++A +a+ ++lel
  EEA20362.1 213 DCLQTLASVRISQTRIDDAQAALSRSLEL 241
                 678899999999***************98 PP

  == domain 4  score: -2.0 bits;  conditional E-value: 5.6
       TPR_2  13 klgdyeeAleafekAlel 30 
                 + +   eAl+ +e+ +  
  EEA20362.1 267 EVQMEVEALHVLERLILE 284
                 555556999999998865 PP

  == domain 5  score: -1.7 bits;  conditional E-value: 4.4
       TPR_2  16 dyeeAleafek 26 
                  +++ l++++k
  EEA20362.1 325 WLKQSLKLYQK 335
                 45666667766 PP

>> TPR_MalT  MalT-like TPR region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.0   8.2e-07   0.00082       7      69 ..      42     104 ..      39     115 .. 0.94
   2 !    6.8   0.2    0.0038       3.7     162     190 ..     213     241 ..     191     246 .. 0.88

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 8.2e-07
    TPR_MalT   7 rAllaiasgdaeralelArqALallpeddllariaatavlGeasllqGdleaAlqalqeaekl 69 
                 +A++ +++g+ae+al lA++ L++++e+     ++a  +++e+++  G+ +aA++++  a++l
  EEA20362.1  42 KATILLQTGQAEAALPLAQRVLEISDEKSPNNTLLAINLVAEIYVELGEIDAARESFLHAVQL 104
                 6999*****************************************************999876 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.0038
    TPR_MalT 162 dayvllarialaqGdleeAetllekaeel 190
                 d++++la ++++q ++++A+++l +  el
  EEA20362.1 213 DCLQTLASVRISQTRIDDAQAALSRSLEL 241
                 89*********************998776 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.3   8.7e-05     0.087       1      65 [.      40     106 ..      40     109 .. 0.85
   2 ?    4.2   0.0     0.069        68       3      27 ..     218     242 ..     217     246 .. 0.84
   3 ?    4.6   0.0     0.053        53      15      48 ..     273     303 ..     263     316 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 8.7e-05
      TPR_16   1 lalaraalragdyddAaaaleaalkrdpssPd.....aaeAllllgdaalrqgrlaeAaalyraalraap 65 
                 l++a+++l+ g+ ++A+++++++l+      +     +  A +l ++++ ++g+ ++A++ ++ a++ +p
  EEA20362.1  40 LEKATILLQTGQAEAALPLAQRVLEIS---DEkspnnTLLAINLVAEIYVELGEIDAARESFLHAVQLDP 106
                 5789********************965...33334489999999***************99988888888 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.069
      TPR_16   3 laraalragdyddAaaaleaalkrd 27 
                 la  ++ + + ddA+aal + l+++
  EEA20362.1 218 LASVRISQTRIDDAQAALSRSLELW 242
                 677788899*************998 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.053
      TPR_16  15 dAaaaleaalkrdpssPdaaeAllllgdaalrqg 48 
                 +A+++le+++  d    +  eA++l g++++ + 
  EEA20362.1 273 EALHVLERLILED---DESIEAWYLGGWCLYLLA 303
                 79***********...88899*********9775 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.9   0.1    0.0014       1.4       4      38 ..      39      77 ..      36      82 .. 0.79
   2 !    9.0   0.0    0.0029       2.9       8      33 ..      82     107 ..      76     110 .. 0.92
   3 ?   -1.9   0.0       8.6   8.5e+03      24      42 ..     124     142 ..     123     143 .. 0.76
   4 ?    3.3   0.0       0.2     2e+02       2      31 ..     213     242 ..     197     252 .. 0.85
   5 ?    0.9   0.0       1.1   1.1e+03      10      40 ..     264     294 ..     258     296 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.0014
      TPR_14  4 llalaeallalGdpdeAiallrrala....laPddaeaw 38
                ll+ a +ll+ G+ ++A+ l++r+l+    + P++  + 
  EEA20362.1 39 LLEKATILLQTGQAEAALPLAQRVLEisdeKSPNNTLLA 77
                6778999******************96555567666655 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.0029
      TPR_14   8 aeallalGdpdeAiallrralalaPd 33 
                 ae++ +lG+ d+A++ +  a++l+P+
  EEA20362.1  82 AEIYVELGEIDAARESFLHAVQLDPE 107
                 899********************996 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 8.6
      TPR_14  24 lrralalaPddaeawllla 42 
                 l ++ +++ +d +aw++ +
  EEA20362.1 124 LAQLSEQGGADSVAWYEKG 142
                 5667788899999998765 PP

  == domain 4  score: 3.3 bits;  conditional E-value: 0.2
      TPR_14   2 eallalaeallalGdpdeAiallrralala 31 
                 + l+ la++   + + d+A a+l r l+l+
  EEA20362.1 213 DCLQTLASVRISQTRIDDAQAALSRSLELW 242
                 5677888888888899**********9976 PP

  == domain 5  score: 0.9 bits;  conditional E-value: 1.1
      TPR_14  10 allalGdpdeAiallrralalaPddaeawll 40 
                 +l++ +   eA+ +l+r++  + ++ eaw+l
  EEA20362.1 264 LLMEVQMEVEALHVLERLILEDDESIEAWYL 294
                 5566666668999****99999999999975 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0     0.028        28       4      30 ..      39      65 ..      36      68 .. 0.89
   2 !   12.2   0.0   0.00012      0.12       8      33 ..      82     107 ..      77     107 .. 0.92
   3 ?   -0.4   0.0       1.2   1.2e+03      16      31 ..     227     242 ..     217     245 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.028
                HHHHHHHHHHTT-HHHHHHHHHHHHHH CS
       TPR_1  4 lynlGnayfklgkydeAleyyekALel 30
                l  ++ ++++ g+ + Al   +++Le+
  EEA20362.1 39 LLEKATILLQTGQAEAALPLAQRVLEI 65
                567899********************8 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 0.00012
                 HHHHHHTT-HHHHHHHHHHHHHHSTT CS
       TPR_1   8 GnayfklgkydeAleyyekALelnPn 33 
                 + +y +lg+ d A e +  A++l+P+
  EEA20362.1  82 AEIYVELGEIDAARESFLHAVQLDPE 107
                 789**********************6 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 1.2
                 -HHHHHHHHHHHHHHS CS
       TPR_1  16 kydeAleyyekALeln 31 
                 + d+A ++ ++ Lel 
  EEA20362.1 227 RIDDAQAALSRSLELW 242
                 579999********96 PP

>> TPR_9  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.2   1.2e-05     0.012       4      62 ..      45     108 ..      42     113 .. 0.94
   2 ?   -2.2   0.0       4.9   4.8e+03      49      69 ..     143     166 ..     139     168 .. 0.66
   3 !    6.6   0.2    0.0088       8.8      13      58 ..     196     241 ..     187     253 .. 0.80
   4 ?    1.7   0.3      0.29   2.9e+02       8      39 ..     268     299 ..     261     305 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 1.2e-05
       TPR_9   4 iaireedweralavverllll.....aPddpeerrdRGlllaqlGclsaAladLeaylalapda 62 
                 i+++  ++e+al  ++r+l +     + ++   +   + ++++lG + aA++ + ++++l+p+ 
  EEA20362.1  45 ILLQTGQAEAALPLAQRVLEIsdeksPNNTLLAINLVAEIYVELGEIDAARESFLHAVQLDPEG 108
                 78999********************99999999*****************************86 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 4.9
       TPR_9  49 ladLeayl...alapdapdaeair 69 
                 + +L + +   ++++ a++a  ++
  EEA20362.1 143 VGALRHIIqslEQCGGADTASVLE 166
                 555555554449999999998876 PP

  == domain 3  score: 6.6 bits;  conditional E-value: 0.0088
       TPR_9  13 ralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylal 58 
                 r+   +   ll+aPd+p+ +   + ++  + ++  A a+L + l+l
  EEA20362.1 196 RCETLITEALLVAPDQPDCLQTLASVRISQTRIDDAQAALSRSLEL 241
                 5556667789******************************998843 PP

  == domain 4  score: 1.7 bits;  conditional E-value: 0.29
       TPR_9   8 eedweralavverllllaPddpeerrdRGlll 39 
                  +   +al v+erl+l + +++e ++  G +l
  EEA20362.1 268 VQMEVEALHVLERLILEDDESIEAWYLGGWCL 299
                 5555689*************999998766555 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   0.0   0.00098      0.98      21      79 ..      34      98 ..      19     101 .. 0.65
   2 ?    0.4   0.0      0.77   7.7e+02      41      80 ..     196     236 ..     193     238 .. 0.78
   3 ?    5.4   0.0     0.021        21      41      69 ..     273     302 ..     270     310 .. 0.69

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00098
                --HHHHHHHHHHHHHTT-HHHHHHHHHCT.SHHHC-H.....HHHHHHHHHHHHTT-HHHHHHHH CS
      ANAPC3 21 espedayllAlclylngqykrAyellrka.klnsksl.....gcrylfAqcllkLkkyeeAiaaL 79
                +++  ++ +A  l+++gq + A+ l+++  ++ ++        +  l A+ +++L++++ A+  +
  EEA20362.1 34 DNATELLEKATILLQTGQAEAALPLAQRVlEISDEKSpnntlLAINLVAEIYVELGEIDAARESF 98
                33333444588999999988888887777544433332333477777778888888888888766 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.77
                 HHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHHH- CS
      ANAPC3  41 rAyellrka.klnskslgcrylfAqcllkLkkyeeAiaaLe 80 
                 r+ +l+ +a   ++  + c+ ++A + + + ++++A aaL+
  EEA20362.1 196 RCETLITEAlLVAPDQPDCLQTLASVRISQTRIDDAQAALS 236
                 55666666656667778999999999999999999999997 PP

  == domain 3  score: 5.4 bits;  conditional E-value: 0.021
                 HHHHHHHCT.SHHHC-HHHHHHHHHHHHHT CS
      ANAPC3  41 rAyellrka.klnskslgcrylfAqcllkL 69 
                 +A+++l+++  ++++s++++yl + cl+ L
  EEA20362.1 273 EALHVLERLiLEDDESIEAWYLGGWCLYLL 302
                 577777777777777777777777777766 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0       9.6   9.5e+03       4      14 ..      46      56 ..      45      57 .. 0.82
   2 !   15.3   0.0   1.2e-05     0.012       2      26 ..      83     107 ..      82     108 .. 0.94
   3 ?   -2.3   0.0       3.9   3.8e+03       6      19 ..     322     335 ..     321     336 .. 0.81

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 9.6
      TPR_11  4 yyeqGkyeeAi 14
                + + G+ e+A+
  EEA20362.1 46 LLQTGQAEAAL 56
                67899999996 PP

  == domain 2  score: 15.3 bits;  conditional E-value: 1.2e-05
      TPR_11   2 dayyeqGkyeeAieaYkkAlkldPd 26 
                  +y+e+G++++A e++  A++ldP+
  EEA20362.1  83 EIYVELGEIDAARESFLHAVQLDPE 107
                 59**********************6 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 3.9
      TPR_11   6 eqGkyeeAieaYkk 19 
                 ++G ++++++ Y+k
  EEA20362.1 322 SRGWLKQSLKLYQK 335
                 57778999999997 PP

>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.2   0.1    0.0097       9.7       9      32 ..      43      66 ..      34      69 .. 0.92
   2 ?    5.0   0.1     0.024        24       1      30 [.      74     103 ..      74     104 .. 0.89
   3 ?    0.8   0.0      0.48   4.8e+02       4      35 ..     214     245 ..     203     254 .. 0.85
   4 ?   -1.0   0.0       1.9   1.9e+03      22      35 ..     323     336 ..     321     337 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0097
      TPR_10  9 analrqrgrydeAealleealair 32
                a +l q+g+ ++A+ l++++l+i 
  EEA20362.1 43 ATILLQTGQAEAALPLAQRVLEIS 66
                78999****************985 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.024
      TPR_10   1 tAsslnNLanalrqrgrydeAealleeala 30 
                 t+ + n  a ++ ++g+ d+A++ + +a++
  EEA20362.1  74 TLLAINLVAEIYVELGEIDAARESFLHAVQ 103
                 67788999***************9999987 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.48
      TPR_10   4 slnNLanalrqrgrydeAealleealairrrl 35 
                 +l  La +  ++ r d+A a l ++l++++ l
  EEA20362.1 214 CLQTLASVRISQTRIDDAQAALSRSLELWQDL 245
                 66677777777889999***999***999976 PP

  == domain 4  score: -1.0 bits;  conditional E-value: 1.9
      TPR_10  22 ealleealairrrl 35 
                 + +l+++l ++++l
  EEA20362.1 323 RGWLKQSLKLYQKL 336
                 56899******997 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.1      0.26   2.6e+02      11      32 ..      34      55 ..      33      56 .. 0.86
   2 ?    3.5   0.0      0.11   1.1e+02       7      34 .]      68      96 ..      58      96 .. 0.70
   3 ?   -1.6   0.0       4.9   4.9e+03      12      21 ..     134     143 ..     133     162 .. 0.74
   4 ?    2.2   0.0       0.3     3e+02       2      33 ..     201     232 ..     200     233 .. 0.85
   5 ?    1.4   0.0      0.54   5.4e+02       3      28 ..     279     304 ..     277     315 .. 0.78

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.26
      TPR_17 11 nnadaynnLAelllknGdlmtA 32
                +na  + ++A++ll+ G+ + A
  EEA20362.1 34 DNATELLEKATILLQTGQAEAA 55
                577778999*********9988 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.11
      TPR_17  7 eldPnn.adaynnLAelllknGdlmtArq 34
                e+ Pnn   a n+ Ae++ ++G+ + Ar+
  EEA20362.1 68 EKSPNNtLLAINLVAEIYVELGEIDAARE 96
                34699955566666779999999999986 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 4.9
      TPR_17  12 nadaynnLAe 21 
                 +++a++++++
  EEA20362.1 134 DSVAWYEKGV 143
                 7899999886 PP

  == domain 4  score: 2.2 bits;  conditional E-value: 0.3
      TPR_17   2 ylkaleldPnnadaynnLAelllknGdlmtAr 33 
                  ++al   P+ +d ++ LA +  ++ + ++A+
  EEA20362.1 201 ITEALLVAPDQPDCLQTLASVRISQTRIDDAQ 232
                 57899999***********9998888888877 PP

  == domain 5  score: 1.4 bits;  conditional E-value: 0.54
      TPR_17   3 lkaleldPnnadaynnLAelllknGd 28 
                 ++ +  d  + +a+++ +++l+ + +
  EEA20362.1 279 ERLILEDDESIEAWYLGGWCLYLLAE 304
                 778888889999*******9885544 PP

>> Cas_Cas02710  CRISPR-associated protein (Cas_Cas02710)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       1.2   1.2e+03     241     272 ..      36      67 ..       7      70 .. 0.75
   2 ?   12.4   0.1   5.1e-05     0.051     188     272 ..     151     243 ..     145     245 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.2
                   HHHHHHHHHH.CTTT-HHHHHHHHHHHHHHHH CS
  Cas_Cas02710 241 ladLlanAerRaaeeryddAalrlYRalELls 272
                   + +Ll+ A    + ++++ A+ ++ R+lE+  
    EEA20362.1  36 ATELLEKATILLQTGQAEAALPLAQRVLEISD 67 
                   56788888888888999999999999999865 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 5.1e-05
                   HHHHHHHHHHHSGGGGGGHHHHH.HHHHHHHHHHHHHHHT-TT-HHH....HHHHH..HH....HHHHHHH.CTTT-HHHHHHHHHHHHHHHH CS
  Cas_Cas02710 188 dalskvleldllevlnaerekle.allevlralekilkekeaaleklrkf.vlall..ad....LlanAerRaaeeryddAalrlYRalELls 272
                   + l+++   d++ vl+++r+kl+ al  v++   + l  +e+a ++ + + + all   d    L   A  R+++ r ddA + l R+lEL +
    EEA20362.1 151 QSLEQCGGADTASVLEEKRKKLAvALCGVVELYMTDLSWEEDAENRCETLiTEALLvaPDqpdcLQTLASVRISQTRIDDAQAALSRSLELWQ 243
                   67889999999999999999997578899999999999999999999998755555342244448889**********************975 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.0      0.49   4.9e+02       4      31 ..      41      68 ..      38      73 .. 0.81
   2 ?    6.6   0.0    0.0088       8.8       2      33 ..      78     107 ..      77     111 .. 0.84
   3 ?    1.6   0.0      0.35   3.5e+02       1      32 [.     214     245 ..     214     251 .. 0.88

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.49
       TPR_7  4 nLarlysrlGdyeeAielyeqsLaltkd 31
                  a +  + G+ e A+ l +++L++ ++
  EEA20362.1 41 EKATILLQTGQAEAALPLAQRVLEISDE 68
                567899999************8888755 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0088
       TPR_7   2 LlnLarlysrlGdyeeAielyeqsLaltkdpe 33 
                 ++  a++y++lG+ + A e +    a+  dpe
  EEA20362.1  78 INLVAEIYVELGEIDAARESFLH--AVQLDPE 107
                 67789****************99..7766665 PP

  == domain 3  score: 1.6 bits;  conditional E-value: 0.35
       TPR_7   1 aLlnLarlysrlGdyeeAielyeqsLaltkdp 32 
                 +L  La+++ ++ + ++A   + +sL+l+ d 
  EEA20362.1 214 CLQTLASVRISQTRIDDAQAALSRSLELWQDL 245
                 577899*********************99875 PP

>> SHNi-TPR  SHNi-TPR
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.1   0.00041      0.41       1      22 [.      82     103 ..      82     103 .. 0.94
   2 ?    3.6   0.0     0.046        46       2      32 ..     213     243 ..     212     249 .. 0.88
   3 ?    0.1   0.4      0.57   5.6e+02      24      35 ..     326     337 ..     326     340 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00041
    SHNi-TPR   1 AdvydlLGEislEnenFpqAve 22 
                 A++y+ LGEi+  +e F  Av+
  EEA20362.1  82 AEIYVELGEIDAARESFLHAVQ 103
                 8****************99986 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.046
    SHNi-TPR   2 dvydlLGEislEnenFpqAveDlrkaLeLre 32 
                 d++ +L+ + + + + ++A+  l ++LeL +
  EEA20362.1 213 DCLQTLASVRISQTRIDDAQAALSRSLELWQ 243
                 99999***********************965 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.57
    SHNi-TPR  24 lrkaLeLreqll 35 
                 l+ +L+L+++l+
  EEA20362.1 326 LKQSLKLYQKLE 337
                 689******985 PP

>> TPR_6  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.1      0.13   1.3e+02       4      28 ..      40      64 ..      39      66 .. 0.86
   2 ?    2.9   0.0       0.2     2e+02       7      23 ..      82      98 ..      80     107 .. 0.83
   3 ?    0.3   0.0       1.4   1.4e+03       6      25 ..     218     237 ..     213     242 .. 0.83
   4 ?   -1.2   0.0       4.3   4.3e+03      13      29 ..     269     284 ..     259     288 .. 0.71
   5 ?    1.4   0.1      0.63   6.3e+02       1      17 [.     290     306 ..     290     312 .. 0.78

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.13
                HHHHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6  4 yklalsyrklgdtdkAlealerlik 28
                +  a  ++++g++++Al + +r+++
  EEA20362.1 40 LEKATILLQTGQAEAALPLAQRVLE 64
                66788899989***********997 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.2
                HHHHHHHHHHHHHHHHH CS
       TPR_6  7 alsyrklgdtdkAleal 23
                a+ y +lg+ d+A+e +
  EEA20362.1 82 AEIYVELGEIDAARESF 98
                899***99*******88 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 1.4
                 HHHHHHHHHHHHHHHHHHHH CS
       TPR_6   6 lalsyrklgdtdkAlealer 25 
                 la  ++++++ d+A +al r
  EEA20362.1 218 LASVRISQTRIDDAQAALSR 237
                 6778889999*****99987 PP

  == domain 4  score: -1.2 bits;  conditional E-value: 4.3
                 HHHHHHHHHHHHHHHHH CS
       TPR_6  13 lgdtdkAlealerlike 29 
                 +    +Al  lerli e
  EEA20362.1 269 Q-MEVEALHVLERLILE 284
                 3.55699999***9965 PP

  == domain 5  score: 1.4 bits;  conditional E-value: 0.63
                 HHHHHHHHHHHHHHHHH CS
       TPR_6   1 dAlyklalsyrklgdtd 17 
                 +A y+ +++++ l +++
  EEA20362.1 290 EAWYLGGWCLYLLAEKE 306
                 799999*****853544 PP

>> TPR_4  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.6     0.017        17       8      26 .]      43      61 ..      39      61 .. 0.88
   2 ?    4.5   0.0     0.068        68       8      22 ..      82      96 ..      82      98 .. 0.92

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.017
       TPR_4  8 ArallalGdldeAraller 26
                A  ll++G++++A+ l++r
  EEA20362.1 43 ATILLQTGQAEAALPLAQR 61
                889************9986 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.068
       TPR_4  8 ArallalGdldeAra 22
                A+ + +lG+ d+Ar+
  EEA20362.1 82 AEIYVELGEIDAARE 96
                8899*********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (402 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       926  (0.0516482); expected 358.6 (0.02)
Passed bias filter:                      560  (0.0312343); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              18  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.46
# Mc/sec: 2616.35
//
Query:       EEA20363.1  [L=489]
Description: histone deacetylase SIR2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.9e-59  200.0   0.0      4e-59  199.5   0.0    1.2  1  SIR2          Sir2 family
     0.0011   18.7   0.1     0.0035   17.1   0.1    1.8  2  DUF592        Protein of unknown function (DUF592)
     0.0029   17.4   0.1          1    9.1   0.0    2.4  2  TPP_enzyme_M  Thiamine pyrophosphate enzyme, central domain
  ------ inclusion threshold ------
       0.14   12.5   0.1       0.32   11.3   0.1    1.6  1  NUMOD1        NUMOD1 domain


Domain annotation for each model (and alignments):
>> SIR2  Sir2 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  199.5   0.0   8.9e-63     4e-59       1     177 []     186     411 ..     186     411 .. 0.98

  Alignments for each domain:
  == domain 1  score: 199.5 bits;  conditional E-value: 8.9e-63
                 -GGGGGGGT---SSS.TTSHHHHSCHHHHSSHHHHHHHHHHHHH..HHHHHHHHHHCCTSS--HHHHHHHHHHHTTCEEEEEES-SSSHHHHTT-S..S CS
        SIR2   1 GAGiStesGipdfRs.keGlyaklakeelaspealfskkllvee..vfyniarellaeeaepnaaHkalkklekkgkllrliTQNiDgLekkaGsk..k 94 
                 GAGiSt++GipdfRs ++Gly++l++ +l++p+++f+++l++e+  +f ++a+++l++e++++++H++++ l++kgkll+++TQNiD++e +aG++  k
  EEA20363.1 186 GAGISTSLGIPDFRSkDTGLYSRLEHLGLSDPQEVFDISLFHEDpsIFFSVAKDILPTEKKFSPTHAFIRLLQDKGKLLTNYTQNIDNIEANAGVNpeK 284
                 9**************99******************************************************************************999* PP

                 EEETTEEEEEEEETTTSBEEECCGGHCHHHCCTT.B-TTTCC..........................................BEEEEE--CTSB-SH CS
        SIR2  95 vvelHGslakakcvkcekkldkeelqeeieaekvpecekcgk..........................................llkpdvvfFGealpd 151
                 +v++HGs+a+a+c+kc+ k+ +++++++i++ k+p c++c++                                          ++kpd++fFGe+lpd
  EEA20363.1 285 IVQCHGSFATATCTKCDFKVPGDAIFDTIKSGKIPLCKRCKEqitlrsqalkrkrssnglqnsrkkrsfdddsdgedydiptpgVMKPDITFFGEDLPD 383
                 **************************************************************************************************7 PP

                 HH.HHHHH.HHHH-SEEEEES--STSTT CS
        SIR2 152 kl.kklie.kveeadlllviGtSlkVap 177
                 ++ ++l+e + e +dl++viGtS+kVap
  EEA20363.1 384 EFgRRLVEeDREVTDLVIVIGTSMKVAP 411
                 7725677789999*************98 PP

>> DUF592  Protein of unknown function (DUF592)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       1.1   4.8e+03      29      52 ..      91     114 ..      87     132 .. 0.62
   2 !   17.1   0.1   7.8e-07    0.0035     119     153 .]     151     185 ..     146     185 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 1.1
      DUF592  29 kedslnarlfLKkyglkkFldkYL 52 
                 +++ +  r+ L++ g++ F ++ +
  EEA20363.1  91 PQEAIAYRKLLREIGKAAFVEETI 114
                 556666677777777777766544 PP

  == domain 2  score: 17.1 bits;  conditional E-value: 7.8e-07
      DUF592 119 ainkvlstrlrlsnfstidhfvdklkkakkilVlt 153
                 +i++  + r++l+++++i++ v+ lkk+k ++V+t
  EEA20363.1 151 VISREFAKRQKLDEYNSIEDAVNLLKKSKNVIVIT 185
                 57777899**************************8 PP

>> TPP_enzyme_M  Thiamine pyrophosphate enzyme, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   0.0   0.00023         1       1      25 [.     168     192 ..     168     199 .. 0.90
   2 !    5.9   0.0    0.0022        10      76     136 ..     395     452 ..     376     453 .. 0.71

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00023
                   HHHHHHHHHH-SSEEEEE-CHHCHT CS
  TPP_enzyme_M   1 iekaaellkaakrpvilvGggvars 25 
                   ie+a++llk++k+++++ G g+++s
    EEA20363.1 168 IEDAVNLLKKSKNVIVITGAGISTS 192
                   799******************9976 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0022
                   HH-SEEEEES-SSSTCCCTTTTTTTTTT-EEEEEESSCCCCTTCC--SEEEECTHHHHHHH CS
  TPP_enzyme_M  76 eeaDlvlalGarfddirttgsepefapeakiihididpaeigknyqvdlaivgdvketlea 136
                   e +Dlv+++G+ ++    ++  p + p  ++ +i i+++ +++    d+ ++gd + ++++
    EEA20363.1 395 EVTDLVIVIGTSMKV-APVADVPSIIPS-TVPQIYISRTPVSHIG-FDIDLLGDSDVVVSE 452
                   458*********988.445556655555.5777777777777764.777888887777665 PP

>> NUMOD1  NUMOD1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   7.1e-05      0.32      12      34 ..     161     183 ..     157     185 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 7.1e-05
      NUMOD1  12 tigkFsSireAakyLgishntIn 34 
                 ++ +++Si +A + L++s+n I 
  EEA20363.1 161 KLDEYNSIEDAVNLLKKSKNVIV 183
                 6789****************995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (489 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       662  (0.0369234); expected 358.6 (0.02)
Passed bias filter:                      573  (0.0319594); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 3366.92
//
Query:       EEA20364.1  [L=460]
Description: RNA methylase family UPF0020 protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.3e-10   40.5   0.0    9.1e-06   25.5   0.0    2.6  3  UPF0020      Putative RNA methylase family UPF0020
    0.00014   21.7   0.1    0.00052   19.8   0.0    1.9  2  N6_N4_Mtase  DNA methylase
    0.00039   19.8   0.0    0.00061   19.2   0.0    1.2  1  N6_Mtase     N-6 DNA Methylase


Domain annotation for each model (and alignments):
>> UPF0020  Putative RNA methylase family UPF0020
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       1.1   6.5e+03      19      38 ..      21      43 ..      20      87 .. 0.69
   2 !   25.5   0.0   1.5e-09   9.1e-06       3      54 ..     196     247 ..     195     268 .. 0.87
   3 !   12.0   0.0   2.1e-05      0.12      95     135 ..     273     315 ..     269     319 .. 0.68

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 1.1
                HHHHHTT--TTS-EEE...TT-T CS
     UPF0020 19 alvrlagwkpgepllD...PmCG 38
                al  lag++ + +l+D   P+C 
  EEA20364.1 21 ALASLAGVDVEFVLYDkysPFCI 43
                67778888888888776667774 PP

  == domain 2  score: 25.5 bits;  conditional E-value: 1.5e-09
                 SS-SS---SS-HHHHHHHHHHTT--TTS-EEETT-TTSHHHHHHHHHHTT-- CS
     UPF0020   3 yRefngpapLketLAaalvrlagwkpgepllDPmCGsGtilIEaallgania 54 
                 +R++   +++ ++L+ +  ++a + pg+ ++DP+ G+G++lI aa  ga   
  EEA20364.1 196 KRKYISTTSMDAELSLVTANMAHAAPGKLFFDPFVGTGSFLIAAAYFGAATL 247
                 68889999*************************************9988765 PP

  == domain 3  score: 12.0 bits;  conditional E-value: 2.1e-05
                 HHHHTT-GGGE...EEEE--GGG--STTS---EEEE-------- CS
     UPF0020  95 Naekagvgdli...efsqadaakLrlkegevdvivtnpPYGerl 135
                 N +++g++d+     +s++ ++ +r +    d i+++pPYG+r 
  EEA20364.1 273 NFQQYGIEDKFldaFMSDLTNTPIR-DVPFLDGIICDPPYGIRE 315
                 7778888876422134455555555.44468**********995 PP

>> N6_N4_Mtase  DNA methylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.0   8.7e-08   0.00052     116     222 ..     143     252 ..      85     257 .. 0.78
   2 ?   -0.8   0.0      0.17     1e+03       3      14 ..     304     315 ..     302     418 .. 0.83

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 8.7e-08
                  .---GGGSSBSS-HHHHHHHHHHCHHHCC-B--BSE....EE-SCCCTTSTTS-CHH..----..SS---HHHHHHHH.HHHS-TT-EEEETT-TTTH CS
  N6_N4_Mtase 116 lkfnldaikvpyeekdklekrgaytskkkgkkiedi....Wdlseiqsnekkskgdt..kkkH..paqkPvallerlI.klstkkgdivlDpFaGSGt 204
                  + +++d+ + +++e++++++++   ++ + k+++++    W   ++ s++ + ++ +  k+k+  ++++ ++l       +   +g++ +DpF G+G+
   EEA20364.1 143 EDYVSDLEEISQQEQQQQKHEH---KQGRHKDLKNVyfarW---ICASSRTMMDKYDlkKRKYisTTSMDAELSLVTAnMAHAAPGKLFFDPFVGTGS 234
                  6779999999**********99...7788888888855556...66666666554446877777789999998877772445678************* PP

                  HHHHHHHTT-EEEEEESS CS
  N6_N4_Mtase 205 TavaakelgrkfiGieie 222
                   ++aa+  g   +G +i+
   EEA20364.1 235 FLIAAAYFGAATLGADID 252
                  *************99987 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.17
                  EEEE--SSSSSC CS
  N6_N4_Mtase   3 livtdpPYntgk 14 
                   i+ dpPY++ +
   EEA20364.1 304 GIICDPPYGIRE 315
                  689999999865 PP

>> N6_Mtase  N-6 DNA Methylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   0.0     1e-07   0.00061      33     170 ..     208     360 ..     190     382 .. 0.78

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 1e-07
    N6_Mtase  33 evsklivellepksgesvyDpacGsggllvqaekvlkee.dgktkelsiyGqeknettyrLakm.Nlllhgieykkvkirlgdtlekpkfekdkkfdvv 129
                 e+s + +++++  +g+  +Dp +G+g++l+ a+ +  ++  +++   s+ G  k ++   ++ + N+   gie k +++ ++d  ++p  +    +d +
  EEA20364.1 208 ELSLVTANMAHAAPGKLFFDPFVGTGSFLIAAAYFGAATlGADIDGRSFKGRHKPTKENPMGLLaNFQQYGIEDKFLDAFMSDLTNTPIRD-VPFLDGI 305
                 678899999***********************9998777566777778889999888888876549999******8888888877777777.9999*** PP

    N6_Mtase 130 vaNppfnqkew.....kektlekderfrea.........vapksnadlafllhii 170
                 +  pp++++e        + + k++ ++++         v+pk+   +  l+h i
  EEA20364.1 306 ICDPPYGIREGlrvlgLREGKSKQPVYKDGvlahtlpdyVPPKKPYGFVTLQHDI 360
                 *******997667777444555555566655555566667777777777777744 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (460 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       812  (0.0452898); expected 358.6 (0.02)
Passed bias filter:                      560  (0.0312343); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.59u 0.27s 00:00:00.86 Elapsed: 00:00:00.44
# Mc/sec: 3139.98
//
Query:       EEA20365.1  [L=208]
Description: HIT domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-16   61.1   0.1      6e-16   59.0   0.1    1.9  2  HIT       HIT domain
     0.0019   18.7   0.0     0.0032   17.9   0.0    1.3  1  DcpS_C    Scavenger mRNA decapping enzyme C-term binding
      0.005   16.7   0.2      0.028   14.3   0.2    2.1  1  CwfJ_C_1  Protein similar to CwfJ C-terminus 1


Domain annotation for each model (and alignments):
>> HIT  HIT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.0   0.1     1e-19     6e-16       5      95 ..      46     143 ..      42     146 .. 0.89
   2 ?   -0.6   0.0      0.37   2.2e+03      55      74 ..     182     201 ..     164     205 .. 0.58

  Alignments for each domain:
  == domain 1  score: 59.0 bits;  conditional E-value: 1e-19
                 -CCEEEE-SSEEEEE-SS-SSSSEEEEEESSTGCSGGGCC...HHHHHHHHHHHHHHHHHHHTCT....TCCCEEEEEEESGGGT-SSSS-EEEEEEC CS
         HIT   5 pstvvyeddlvlafldidpkapghlLvipkkhlselhdlt...eeelakllsavkkvakalqkkf....knkglrvvinngahagqsvahlHiHvipr 95 
                  + +v+ +++vlafldi p ++gh+Lv +++h++++ +l     eel++ l +v +v   +        ++   ++v nng+ a q+v+h+H+H+ipr
  EEA20365.1  46 HAFLVLSTKYVLAFLDIMPLSKGHILVTTREHYEKVGELGvriGEELGRWLPIVSRVGMRVIFGQssavEEHHWNLVQNNGERAAQVVPHVHFHIIPR 143
                 577899**********************************99999*******999998776432245668999************************8 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.37
                 HHHHHHHHHTCTTCCCEEEE CS
         HIT  55 vkkvakalqkkfknkglrvv 74 
                  +++a++++++ +++g+ ++
  EEA20365.1 182 REELAREVKRVKQEEGIDLD 201
                 24677777777777776665 PP

>> DcpS_C  Scavenger mRNA decapping enzyme C-term binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.0   5.4e-07    0.0032      14     100 ..      47     141 ..      36     148 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 5.4e-07
                 B-EEEE-SSEEEEE-SS-SSSEEEEEEESS---SGGG-....-TTTTTHHHHHHHHHHHHHHHTT-T....-EEEEE--SCCCT--S-S--EEEE CS
      DcpS_C  14 ervvyedekfvvlkDikpkaklhllvipkrdikslrdL....tkehlpllkemrekakkvieekyne....vdaeelrvgvhyqPsvyhlHlHvi 100
                 + +v++++ ++++ Di p +k h+lv  +++ +++ +L     +e   +l  + +++  vi  + ++          + g  +++ v h+H+H+i
  EEA20365.1  47 AFLVLSTKYVLAFLDIMPLSKGHILVTTREHYEKVGELgvriGEELGRWLPIVSRVGMRVIFGQSSAveehHWNLVQNNGERAAQVVPHVHFHII 141
                 4457788999***************************9998899999**************9999885555445567889**************9 PP

>> CwfJ_C_1  Protein similar to CwfJ C-terminus 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.2   4.7e-06     0.028      24      76 ..      44      97 ..      38     154 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 4.7e-06
                -SS--S-B-SSEEEE---.S-SSTT-EEEEESS--SSTTSS-HHHHHHHHHHHH CS
    CwfJ_C_1 24 ekhlivsignkvYlalpk.gpLssgHvliipieHisallsldeevldeirkfrk 76
                 +h  + ++ k  la    +pLs+gH+l+++ eH +++ +l   + +e+ ++  
  EEA20365.1 44 RSHAFLVLSTKYVLAFLDiMPLSKGHILVTTREHYEKVGELGVRIGEELGRWLP 97
                5677777888888888888*******************9999999999998865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (208 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       662  (0.0369234); expected 358.6 (0.02)
Passed bias filter:                      579  (0.032294); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 1377.45
//
Query:       EEA20366.1  [L=485]
Description: G2/M-specific cyclin NimE [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-46  157.8   0.1    6.7e-45  151.9   0.0    2.4  2  Cyclin_N  Cyclin, N-terminal domain
      4e-35  120.5   0.2    7.7e-35  119.6   0.2    1.5  1  Cyclin_C  Cyclin, C-terminal domain


Domain annotation for each model (and alignments):
>> Cyclin_N  Cyclin, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  151.9   0.0   7.5e-49   6.7e-45       1     127 []     224     350 ..     224     350 .. 0.99
   2 !    3.6   0.0     0.006        54      36     122 ..     356     439 ..     352     450 .. 0.76

  Alignments for each domain:
  == domain 1  score: 151.9 bits;  conditional E-value: 7.5e-49
                 HHHHHHHHHHCHTS-STTCTTCTSSS-HHHHHHHHHHHHHHHHHTT--TTHHHHHHHHHHHHHHHS---CCCHHHHHHHHHHHHHHHHSSS---HHHHH CS
    Cyclin_N   1 dilknlieqelkflpkpdyldqqpelnpemRailidwlvevaekfkltpetlflavnyldRflskksvpkdklqlvgatcLllAaKveeisppkledlv 99 
                 di+++l+  e+++lp+pdy+d qpel+++mR ilidwl+ev+++f+l petlfl+vn++dRfls ++v+ d+lqlvg+t++++A+K+ee+ +p++ ++ 
  EEA20366.1 224 DIFDYLKDLEHETLPSPDYIDHQPELEWKMRGILIDWLIEVHASFRLLPETLFLTVNIIDRFLSAEIVSLDRLQLVGVTAMFIASKYEEVLSPHVANFS 322
                 89************************************************************************************************* PP

                 HHTTTSS-HHHHHHHHHHHHHHTTT--- CS
    Cyclin_N 100 yitdeafteeeilemErliLetLnfdls 127
                  ++de+f+ +eil++Er++L tLn+++s
  EEA20366.1 323 QVADETFSDKEILDAERHVLATLNYNMS 350
                 **************************95 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.006
                 HHHHHHHHHTT--TTHHHHHHHHHHHHHHHS---CCCHHHHHHHHHHHHHHHHSSS---HHHHHHHTTTSS-HHHHHHHHHHHHHHT CS
    Cyclin_N  36 dwlvevaekfkltpetlflavnyldRflskksvpkdklqlvgatcLllAaKveeisppkledlvyitdeafteeeilemErliLetL 122
                 ++l ++++  + + +t  l   +++  l  +++  +k   v+a++++lA  + +  p     l+++++  +teeei+ + +l++++L
  EEA20366.1 356 NFLRRISKADNYDIQTRTLGKYLMEISLLDHKFMPYKQSHVAAAAMYLARLILDR-PGWDATLAHYSG--YTEEEIQPVFLLMVDYL 439
                 677777777777788888888888888888999999999*********9777444.666666777755..77777776666666665 PP

>> Cyclin_C  Cyclin, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.6   0.2   8.6e-39   7.7e-35       1     116 [.     352     463 ..     352     466 .. 0.96

  Alignments for each domain:
  == domain 1  score: 119.6 bits;  conditional E-value: 8.6e-39
                 --HHHHHHHHHCCSSHT.-HCCHHCHHCHHHHHHCSCCHCCS-HHHHHHHHHHHCCHHHHS--S-HHHHHHC---HHHHHHHHHHHHHHHHHHHGSS-- CS
    Cyclin_C   1 ptplsFlrrflkaadasedselrtlakylleltlldydflsyppSliAaaalllarstlnspewtetlehytgyskedlkpcvelilellssapssklq 99 
                 p p++Flrr++ka+++  d+++rtl kyl+e++lld++f+ y+ S++Aaaa++lar +l++p w+ tl hy+gy++e+++p+  l++++l  ++s  ++
  EEA20366.1 352 PNPMNFLRRISKADNY--DIQTRTLGKYLMEISLLDHKFMPYKQSHVAAAAMYLARLILDRPGWDATLAHYSGYTEEEIQPVFLLMVDYL--HRSVAHE 446
                 89***********888..999*********************************************************************..77999** PP

                 HHCCCCTCGGGCCCGGS CS
    Cyclin_C 100 avrrkyssskfhkvstl 116
                 a+++ky+s+kf k+s +
  EEA20366.1 447 AFFKKYASKKFLKASIV 463
                 ************98765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (485 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       997  (0.0556082); expected 358.6 (0.02)
Passed bias filter:                      400  (0.0223102); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.29s 00:00:00.89 Elapsed: 00:00:00.48
# Mc/sec: 3018.09
//
Query:       EEA20367.1  [L=480]
Description: G2/M-specific cyclin NimE [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-46  157.8   0.1    6.6e-45  151.9   0.0    2.4  2  Cyclin_N  Cyclin, N-terminal domain
    3.9e-35  120.5   0.2    7.6e-35  119.6   0.2    1.5  1  Cyclin_C  Cyclin, C-terminal domain


Domain annotation for each model (and alignments):
>> Cyclin_N  Cyclin, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  151.9   0.0   7.4e-49   6.6e-45       1     127 []     219     345 ..     219     345 .. 0.99
   2 !    3.6   0.0    0.0059        53      36     122 ..     351     434 ..     347     445 .. 0.76

  Alignments for each domain:
  == domain 1  score: 151.9 bits;  conditional E-value: 7.4e-49
                 HHHHHHHHHHCHTS-STTCTTCTSSS-HHHHHHHHHHHHHHHHHTT--TTHHHHHHHHHHHHHHHS---CCCHHHHHHHHHHHHHHHHSSS---HHHHH CS
    Cyclin_N   1 dilknlieqelkflpkpdyldqqpelnpemRailidwlvevaekfkltpetlflavnyldRflskksvpkdklqlvgatcLllAaKveeisppkledlv 99 
                 di+++l+  e+++lp+pdy+d qpel+++mR ilidwl+ev+++f+l petlfl+vn++dRfls ++v+ d+lqlvg+t++++A+K+ee+ +p++ ++ 
  EEA20367.1 219 DIFDYLKDLEHETLPSPDYIDHQPELEWKMRGILIDWLIEVHASFRLLPETLFLTVNIIDRFLSAEIVSLDRLQLVGVTAMFIASKYEEVLSPHVANFS 317
                 89************************************************************************************************* PP

                 HHTTTSS-HHHHHHHHHHHHHHTTT--- CS
    Cyclin_N 100 yitdeafteeeilemErliLetLnfdls 127
                  ++de+f+ +eil++Er++L tLn+++s
  EEA20367.1 318 QVADETFSDKEILDAERHVLATLNYNMS 345
                 **************************95 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.0059
                 HHHHHHHHHTT--TTHHHHHHHHHHHHHHHS---CCCHHHHHHHHHHHHHHHHSSS---HHHHHHHTTTSS-HHHHHHHHHHHHHHT CS
    Cyclin_N  36 dwlvevaekfkltpetlflavnyldRflskksvpkdklqlvgatcLllAaKveeisppkledlvyitdeafteeeilemErliLetL 122
                 ++l ++++  + + +t  l   +++  l  +++  +k   v+a++++lA  + +  p     l+++++  +teeei+ + +l++++L
  EEA20367.1 351 NFLRRISKADNYDIQTRTLGKYLMEISLLDHKFMPYKQSHVAAAAMYLARLILDR-PGWDATLAHYSG--YTEEEIQPVFLLMVDYL 434
                 677777777777788888888888888888999999999*********9777444.666666777755..77777776666666665 PP

>> Cyclin_C  Cyclin, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.6   0.2   8.5e-39   7.6e-35       1     116 [.     347     458 ..     347     461 .. 0.96

  Alignments for each domain:
  == domain 1  score: 119.6 bits;  conditional E-value: 8.5e-39
                 --HHHHHHHHHCCSSHT.-HCCHHCHHCHHHHHHCSCCHCCS-HHHHHHHHHHHCCHHHHS--S-HHHHHHC---HHHHHHHHHHHHHHHHHHHGSS-- CS
    Cyclin_C   1 ptplsFlrrflkaadasedselrtlakylleltlldydflsyppSliAaaalllarstlnspewtetlehytgyskedlkpcvelilellssapssklq 99 
                 p p++Flrr++ka+++  d+++rtl kyl+e++lld++f+ y+ S++Aaaa++lar +l++p w+ tl hy+gy++e+++p+  l++++l  ++s  ++
  EEA20367.1 347 PNPMNFLRRISKADNY--DIQTRTLGKYLMEISLLDHKFMPYKQSHVAAAAMYLARLILDRPGWDATLAHYSGYTEEEIQPVFLLMVDYL--HRSVAHE 441
                 89***********888..999*********************************************************************..77999** PP

                 HHCCCCTCGGGCCCGGS CS
    Cyclin_C 100 avrrkyssskfhkvstl 116
                 a+++ky+s+kf k+s +
  EEA20367.1 442 AFFKKYASKKFLKASIV 458
                 ************98765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (480 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       966  (0.0538792); expected 358.6 (0.02)
Passed bias filter:                      399  (0.0222544); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.23s 00:00:00.82 Elapsed: 00:00:00.42
# Mc/sec: 3436.01
//
Query:       EEA20368.1  [L=409]
Description: 50S ribosomal protein L2 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.6e-52  176.3   2.8    4.2e-51  172.4   2.1    2.6  2  Ribosomal_L2_C  Ribosomal Proteins L2, C-terminal domain
    1.8e-27   95.1   1.2    4.2e-27   93.9   1.2    1.6  1  Ribosomal_L2    Ribosomal Proteins L2, RNA binding domain
  ------ inclusion threshold ------
       0.19   11.9   0.3       0.34   11.1   0.3    1.3  1  NusG_II         NusG domain II


Domain annotation for each model (and alignments):
>> Ribosomal_L2_C  Ribosomal Proteins L2, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       1.6   9.8e+03      16      31 ..     141     156 ..     137     166 .. 0.75
   2 !  172.4   2.1     7e-55   4.2e-51       2     126 .]     212     374 ..     211     374 .. 0.98

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 1.6
                     -BBSE-SSTTS--SSS CS
  Ribosomal_L2_C  16 ivhnielkpgkggkla 31 
                     +v  ie  pg+ +++a
      EEA20368.1 141 VVERIEHDPGRTAHIA 156
                     6778899999888876 PP

  == domain 2  score: 172.4 bits;  conditional E-value: 7e-55
                     SSS-EBSSSS-TTB-BBSE-SSTTS--SSS-SSSB-EEBB-......................................B.SSEEEEEETTS-EE CS
  Ribosomal_L2_C   2 vGnvlplknipeGtivhnielkpgkggklarsaGtyaqvva......................................kegkkvtvklpSgevr 58 
                     +Gn+lpl++ip+Gt+++n+ l+pgkgg+l+rsaGt+a+v+a                                      ++ ++vt++l+Sgevr
      EEA20368.1 212 RGNCLPLHMIPVGTLIFNVGLRPGKGGQLCRSAGTFATVIAkgteqqkneerkqqleaeagtgeteqkrltqrdyqkikRDANHVTIRLQSGEVR 306
                     59**********************************************************************9999774469************* PP

                     EEETTSBEBES-BS-TTCTT----STTHHHHTTBS----SSSS-TTTSSS--SSSS--SSSSTEETTC CS
  Ribosomal_L2_C  59 kvssecrAtiGvvsngehkekklgkAgrkrwlgrrpkvrGvamnpvdHphGGGeGktksrkapvspwg 126
                     +++ +c+At+Gv sn++ + ++lgkAgr+rwl++rp+vrG+amn++dHphGGG+Gk+k++ +p spwg
      EEA20368.1 307 LIHMDCCATVGVASNPNYQYTQLGKAGRSRWLNIRPTVRGLAMNAMDHPHGGGRGKSKGNVHPKSPWG 374
                     *******************************************************************8 PP

>> Ribosomal_L2  Ribosomal Proteins L2, RNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.9   1.2     7e-31   4.2e-27       1      76 [.     107     182 ..     107     183 .. 0.95

  Alignments for each domain:
  == domain 1  score: 93.9 bits;  conditional E-value: 7e-31
                   TB-TT--BSSTT--------EE-B--S---SS--EEEEEEE--TT-SS-EEEEEETT.TEEEEEE--SS--SS-EE- CS
  Ribosomal_L2   1 GrnnsgritvrhrggGhkkkyrlidfkrnkekvkgkVveieyDpgRsApiAlvkyed.gekryiiapeglkvGdtvv 76 
                   Grn+sgritvrhrggGhk+++r++df+rn  + +++V++ie+DpgR+A+iAlv  ++ g+ +yi+a++g+++Gd++ 
    EEA20368.1 107 GRNHSGRITVRHRGGGHKRRIRIVDFARNDPG-PHVVERIEHDPGRTAHIALVRAKNnGKLSYILAADGMRAGDVIQ 182
                   9***************************8555.69*******************999999**************995 PP

>> NusG_II  NusG domain II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.3   5.7e-05      0.34      14      78 ..     255     316 ..     243     325 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 5.7e-05
                 ...........EEEEEETTEEEEEEEE-TT--EEEEEEE-TTSEEEEEEETTEEEEEEE-SSS-H CS
     NusG_II  14 llaakkkkeaktavitvdgkvvktisLskedeektieiegeegtnvieikdgkvrvkeadCpdki 78 
                   ++k+++++++++ +    ++++ +L++  + ++i+   +  + +i+ + g+vr++++dC   +
  EEA20368.1 255 TEQQKNEERKQQLEAEAGTGETEQKRLTQR-DYQKIK--RDANHVTIRLQSGEVRLIHMDCCATV 316
                 457788888888999999999999***444.344444..5666679999************7665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (409 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       874  (0.0487478); expected 358.6 (0.02)
Passed bias filter:                      631  (0.0351944); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.56u 0.29s 00:00:00.85 Elapsed: 00:00:00.43
# Mc/sec: 2854.23
//
Query:       EEA20369.1  [L=868]
Description: C6 transcription factor Prf, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.7e-14   52.1   0.0    1.2e-13   50.7   0.0    1.7  1  Fungal_trans  Fungal specific transcription factor domain
    2.8e-10   40.2   9.8      5e-10   39.3   9.8    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
     0.0064   16.7   0.0      0.014   15.6   0.0    1.5  1  DUF4691       Domain of unknown function (DUF4691)


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.7   0.0     2e-17   1.2e-13       2     190 ..     204     385 ..     203     413 .. 0.86

  Alignments for each domain:
  == domain 1  score: 50.7 bits;  conditional E-value: 2e-17
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeili.....hedfsspssslwi 93 
                   d+ff  +hp  p++h+p f+ +    n  +    + +l + + al+a+ +++ +  +      e   ++    ra+++i       + +  +s + +
    EEA20369.1 204 DIFFAKIHPSHPMIHRPRFFASM---NLAPHMRPPVCLRYIMWALAASITPKYSFLE------EH-LYA----RARKYIhldemKGHGEHMVS-VSH 285
                   79*********************...7777777777777999999999888766554......21.334....88888887775444445555.88* PP

  Fungal_trans  94 lqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkks....lwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLP 186
                   +q+++l++lye+     + ++  +g   r+a  + ++r      + +     ++ w+e +e+rrR++w++F+ D++ ++ +G p  +d+ +i ++LP
    EEA20369.1 286 CQAWVLISLYEFKQMFFPRAWVSVGRGARMAAMMCFNRLDGVGLDVKhcvpPPVDWVE-REERRRTFWMCFSQDRYASIGTGWPMVFDERDIMTNLP 381
                   ***************999*******************999887766699999999999.**************************99********** PP

  Fungal_trans 187 cddd 190
                    +++
    EEA20369.1 382 SSEE 385
                   9998 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.3   9.8   8.4e-14     5e-10       2      40 .]      50      87 ..      49      87 .. 0.95

  Alignments for each domain:
  == domain 1  score: 39.3 bits;  conditional E-value: 8.4e-14
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCCEE CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfysesskrs 40
                aC+ Crk+K +Cd++kP+C+ C++++ +Ct y+e +k+s
  EEA20369.1 50 ACIVCRKRKLRCDGQKPSCGTCARVGHNCT-YDEVRKKS 87
                9*****************************.99988875 PP

>> DUF4691  Domain of unknown function (DUF4691)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   2.3e-06     0.014      75     143 ..      58     122 ..      51     126 .. 0.86

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 2.3e-06
     DUF4691  75 kleeerlkpevealeergPrpvasivrpshgpkrkpvshkahpkaeaelppg.lllqkeepegsqsepsp 143
                 kl+ ++ kp   +    g   +   vr + gpkr  v      + ea l++  +ll++ epe+s +eps 
  EEA20369.1  58 KLRCDGQKPSCGTCARVGHNCTYDEVRKKSGPKRGYV-----KQLEARLAQVeILLKNQEPENSWNEPSH 122
                 5666777777777778888888899*********999.....889****9976***************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (868 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       478  (0.0266607); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.30s 00:00:00.95 Elapsed: 00:00:00.47
# Mc/sec: 5558.71
//
Query:       EEA20370.1  [L=363]
Description: WD repeat-containing protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.5e-26   92.1   7.2    1.2e-05   26.0   0.0    7.1  7  WD40           WD domain, G-beta repeat
    1.6e-19   70.0   0.0    0.00041   20.6   0.0    5.8  5  ANAPC4_WD40    Anaphase-promoting complex subunit 4 WD40 doma
    2.9e-08   32.6   0.0    0.00047   18.8   0.0    2.1  2  Cytochrom_D1   Cytochrome D1 heme domain
    2.8e-05   24.1   0.0        0.3   11.0   0.1    3.0  2  eIF2A          Eukaryotic translation initiation factor eIF2A
     0.0014   17.8   0.0      0.052   12.6   0.0    2.4  2  Coatomer_WDAD  Coatomer WD associated region
  ------ inclusion threshold ------
      0.011   14.5   0.4        0.2   10.3   0.1    2.1  2  Nup160         Nucleoporin Nup120/160
       0.11   11.4   0.0       0.24   10.3   0.0    1.5  1  PALB2_WD40     Partner and localizer of BRCA2 WD40 domain
       0.17   10.8   0.1        6.5    5.6   0.0    3.0  4  Ge1_WD40       WD40 region of Ge1, enhancer of mRNA-decapping


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0   0.0   5.2e-09   1.2e-05       9      38 .]      38      66 ..      29      66 .. 0.89
   2 !   20.6   0.0   2.7e-07    0.0006       5      38 .]      76     111 ..      73     111 .. 0.83
   3 ?    3.4   0.1     0.074   1.7e+02      15      34 ..     129     148 ..     116     149 .. 0.76
   4 !    9.3   0.0   0.00095       2.1      20      37 ..     206     222 ..     187     223 .. 0.86
   5 !   19.3   0.0   6.6e-07    0.0015       2      38 .]     228     265 ..     227     265 .. 0.89
   6 !    9.5   0.1   0.00082       1.8       3      29 ..     271     298 ..     269     301 .. 0.73
   7 ?    0.7   0.0      0.51   1.1e+03      13      26 ..     327     340 ..     309     352 .. 0.75

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 5.2e-09
                SSSSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  9 GHssvtslafspdgawlasGsdDgtvriWd 38
                 H  ++ la++p g+++a+Gs ++t+riW+
  EEA20370.1 38 SH-TIRTLAWNPTGTLIATGSANRTLRIWN 66
                35.5*************************8 PP

  == domain 2  score: 20.6 bits;  conditional E-value: 2.7e-07
                 EEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS
        WD40   5 rtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 
                 ++l+GH  ++  + f+p  +  las+s Dgtvr+Wd
  EEA20370.1  76 TELRGHtAGIEKVIFNPVRDAeLASCSSDGTVRFWD 111
                 5799**888**99766666669999988*******9 PP

  == domain 3  score: 3.4 bits;  conditional E-value: 0.074
                 EEEEETTSSEEEEEETTSEE CS
        WD40  15 slafspdgawlasGsdDgtv 34 
                  l++s dg+ ++ G +D t+
  EEA20370.1 129 TLSWSADGRVVMVGRKDDTL 148
                 356********99*989886 PP

  == domain 4  score: 9.3 bits;  conditional E-value: 0.00095
                 TTSSEEEEEETTSEEEEE CS
        WD40  20 pdgawlasGsdDgtvriW 37 
                 pd ++la+ + Dgtvri+
  EEA20370.1 206 PDLDLLATTG-DGTVRIF 222
                 77799**999.******7 PP

  == domain 5  score: 19.3 bits;  conditional E-value: 6.6e-07
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 ++++tl +H s   +la  p g++la G+ D  + +Wd
  EEA20370.1 228 NLQHTLNAHsSACLALALAPTGRYLAVGGSDALISLWD 265
                 789******55578999*********9977*******9 PP

  == domain 6  score: 9.5 bits;  conditional E-value: 0.00082
                 EEEEEESS.SS.EEEEEEETTSSEEEEEE CS
        WD40   3 clrtltGH.ss.vtslafspdgawlasGs 29 
                 c rt +   ++ ++++++s dg++l +Gs
  EEA20370.1 271 CRRTVSSEgGGtIRGVSWSFDGRFL-CGS 298
                 666766553225************9.586 PP

  == domain 7  score: 0.7 bits;  conditional E-value: 0.51
                 EEEEEEETTSSEEE CS
        WD40  13 vtslafspdgawla 26 
                 v ++a++p   wla
  EEA20370.1 327 VPAVAWHPTRYWLA 340
                 44678*****9986 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   7.7e-06     0.017      38      76 ..      38      76 ..      23      91 .. 0.86
   2 !    8.3   0.0    0.0012       2.8      50      79 ..      95     124 ..      74     129 .. 0.79
   3 !   10.3   0.0    0.0003      0.67      39      71 ..     125     157 ..     122     171 .. 0.87
   4 !    8.7   0.0   0.00096       2.2       6      69 ..     207     268 ..     205     278 .. 0.69
   5 !   20.6   0.0   1.8e-07   0.00041      35      90 ..     277     333 ..     268     335 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 7.7e-06
  ANAPC4_WD40 38 dsevrsLaWkpdgklLavaysdgevrlldaesgkvvhsl 76
                 ++++r LaW+p g+l+a + ++ ++r+ + e ++   s 
   EEA20370.1 38 SHTIRTLAWNPTGTLIATGSANRTLRIWNPERANARYST 76
                 5789************************99988876665 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.0012
  ANAPC4_WD40  50 gklLavaysdgevrlldaesgkvvhslsvk 79 
                  +  La   sdg+vr+ d+ s+++v++l+v+
   EEA20370.1  95 DAELASCSSDGTVRFWDVRSKTCVSKLDVG 124
                  566999*******************99886 PP

  == domain 3  score: 10.3 bits;  conditional E-value: 0.0003
  ANAPC4_WD40  39 sevrsLaWkpdgklLavaysdgevrlldaesgk 71 
                  +e   L+W+ dg++ +v+ +d ++  +++es+ 
   EEA20370.1 125 GEAFTLSWSADGRVVMVGRKDDTLVPVSVESTS 157
                  56678*******************999999876 PP

  == domain 4  score: 8.7 bits;  conditional E-value: 0.00096
  ANAPC4_WD40   6 tmDLiAlatedgellvfRlngqrvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaes 69 
                    DL+A  t dg +++f     ++ ++  ++++s   +La  p g+ Lav+ sd  ++l d  +
   EEA20370.1 207 DLDLLA-TTGDGTVRIFSYPSFNLQHT-LNAHSSACLALALAPTGRYLAVGGSDALISLWDTTD 268
                  566666.35666676666533333222.3567888889999999*******9999999998765 PP

  == domain 5  score: 20.6 bits;  conditional E-value: 1.8e-07
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysd...gevrlldaesgkvvhslsvksekavtclgWg 90 
                  ++ ++++r+++W+ dg++L+ + ++   + +++++ae+g+ vh++ v++   v  + W 
   EEA20370.1 277 SEGGGTIRGVSWSFDGRFLCGSSEEvgpNGLEIFHAETGDSVHKIAVSAG--VPAVAWH 333
                  57899***************9877644479****************9998..8888885 PP

>> Cytochrom_D1  Cytochrome D1 heme domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   0.0   2.9e-05     0.064      54      95 ..     102     143 ..      96     172 .. 0.94
   2 !   18.8   0.0   2.1e-07   0.00047       6     116 ..     208     322 ..     204     329 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 2.9e-05
                   ETTSEEEEEESSSSSEEEEEE-SSEEEEEEE--TTSEEEEEE CS
  Cytochrom_D1  54 gRDgkvtliDLwakeivaevkiGlnarsvavSqddryvivgn 95 
                   + Dg+v   D+  k+ v ++ +G++a  +  S d+r v+vg 
    EEA20370.1 102 SSDGTVRFWDVRSKTCVSKLDVGGEAFTLSWSADGRVVMVGR 143
                   77**************************************95 PP

  == domain 2  score: 18.8 bits;  conditional E-value: 2.1e-07
                   EEEEEEGGGTEEEEEETTT-SEEEEEE-STTEEEEEE-TT.SSEEEEEETTSEEEEEESSSSSEEEEE..E-SSEEEEEEE--TTSEEEEEEEE..T CS
  Cytochrom_D1   6 lfvvverdagkvalldgdskeilavletgyalHisrvfasdgRyvyvigRDgkvtliDLwakeivaev..kiGlnarsvavSqddryvivgnYl..P 98 
                   l  +   ++g v++    s++  ++l+++     +   a+ gRy+ v g D+ ++l D       ++v  + G+  r+v  S d+r++ +++ +  P
    EEA20370.1 208 LDLLATTGDGTVRIFSYPSFNLQHTLNAHSSACLALALAPTGRYLAVGGSDALISLWDTTDWVCRRTVssEGGGTIRGVSWSFDGRFLCGSSEEvgP 304
                   55667788999999999999999999999999999999*****************9998666666666215688999************99865459 PP

                   TEEEEEETTT--EEEEEE CS
  Cytochrom_D1  99 gqlvildaetLelvkvis 116
                    +l i+ aet + v++i+
    EEA20370.1 305 NGLEIFHAETGDSVHKIA 322
                   9*********99998875 PP

>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.1   0.00013       0.3      61     159 ..      40     140 ..      23     144 .. 0.71
   2 !    8.9   0.0   0.00057       1.3      85     185 ..     219     320 ..     209     325 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00013
                 .EEEEEE-TTSS-EEEEESSSSCEEEEEECS.CEEEEEEE....EES--EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE-.TT--EEEE-T CS
       eIF2A  61 pihdvaWspkskefaviyGkmpakvslfdlk.vkviskle....eqkrNtiffspkgklvllaGfgnlaGeleiwdvkkkkkiakaea.anatlvewsp 153
                  i  +aW+p+++  ++  G ++++  +++ + +++ +++e    ++    ++f+p     l +   +  G++ +wdv +k++++k++   +a ++ ws 
  EEA20370.1  40 TIRTLAWNPTGT--LIATGSANRTLRIWNPErANARYSTElrghTAGIEKVIFNPVRDAELAS-C-SSDGTVRFWDVRSKTCVSKLDVgGEAFTLSWSA 134
                 577888888887..5668888888888888444444333311113445667777765543333.2.3469****************97358999***** PP

                 TSSEEE CS
       eIF2A 154 dgryvl 159
                 dgr v+
  EEA20370.1 135 DGRVVM 140
                 ***998 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.00057
                 EEEEEC.SCEEEEEEEEES--..EEEE-TTSSEEEEE-TTSSS-EEEEEETT...TTEEEEEEE-TT--EEEE-TTSSEEEEEE-TTT-SSS-EEEEEE CS
       eIF2A  85 vslfdl.kvkviskleeqkrN..tiffspkgklvllaGfgnlaGeleiwdvk...kkkkiakaeaanatlvewspdgryvlTattaprlrvdngfkiws 177
                 v +f+    ++ ++l++++    ++   p+g++++++G   l   +++wd++    ++++++    +   v ws dgr++  ++        ng++i++
  EEA20370.1 219 VRIFSYpSFNLQHTLNAHSSAclALALAPTGRYLAVGGSDAL---ISLWDTTdwvCRRTVSSEGGGTIRGVSWSFDGRFLCGSSEE---VGPNGLEIFH 311
                 6666664355556666555551156789**************...999999933223344444444566799*******9988766...3468888888 PP

                 T.TTEEEEE CS
       eIF2A 178 y.sGklvyk 185
                   +G+ v+k
  EEA20370.1 312 AeTGDSVHK 320
                 734777776 PP

>> Coatomer_WDAD  Coatomer WD associated region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.0   2.3e-05     0.052     116     169 ..      90     149 ..      12     181 .. 0.74
   2 ?    2.8   0.0     0.022        49     125     159 ..     305     339 ..     282     346 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 2.3e-05
                    X.....XXXXXXXXXX.XXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXX CS
  Coatomer_WDAD 116 g.....GalLgvksegsvsfYDweqgklvrridvkk.vknVvwsddgelvalvskdtvyi 169
                            l   +s+g+v f+D+ +++ v+++dv        ws dg +v++  kd++ +
     EEA20370.1  90 FnpvrdAELASCSSDGTVRFWDVRSKTCVSKLDVGGeAFTLSWSADGRVVMVGRKDDTLV 149
                    3466667777789999******************9668*************998888765 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.022
                    XX.XXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXX CS
  Coatomer_WDAD 125 egsvsfYDweqgklvrridvkk.vknVvwsddgelv 159
                    + ++ +++ e+g  v++i v++ v  V w +++  +
     EEA20370.1 305 N-GLEIFHAETGDSVHKIAVSAgVPAVAWHPTRYWL 339
                    3.499****************99******9887655 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.0     0.023        50     231     249 ..      51      69 ..      38      88 .. 0.80
   2 ?   10.3   0.1   8.9e-05       0.2     233     259 ..      98     124 ..      82     188 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.023
                 TEEEEEETT-EEEEEETTT CS
      Nup160 231 tylfalsrdgkLrvWnllt 249
                 t++++ s +++Lr+Wn + 
  EEA20370.1  51 TLIATGSANRTLRIWNPER 69 
                 789999*********9665 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 8.9e-05
                 EEEEETT-EEEEEETTTTEEEEEEE-- CS
      Nup160 233 lfalsrdgkLrvWnlltgkclatidll 259
                 l++ s+dg++r W++++++c++  d  
  EEA20370.1  98 LASCSSDGTVRFWDVRSKTCVSKLDVG 124
                 78899****************988865 PP

>> PALB2_WD40  Partner and localizer of BRCA2 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   0.00011      0.24     289     347 ..      92     148 ..      64     151 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00011
  PALB2_WD40 289 dvkdqlaaavltsGaiavWdlllghctalllpesdesWslvrWsgtdsqllaGqkdGsv 347
                  v+d+  a+  + G++ +Wd+   +c + l    +e ++l  Ws+    ++ G+kd ++
  EEA20370.1  92 PVRDAELASCSSDGTVRFWDVRSKTCVSKLDV-GGEAFTL-SWSADGRVVMVGRKDDTL 148
                 58999999999***************988864.4566665.7*************9875 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0      0.25   5.6e+02     189     215 ..      40      66 ..      17      81 .. 0.74
   2 ?    5.6   0.0    0.0029       6.5     186     217 ..      80     113 ..      66     120 .. 0.74
   3 ?    0.4   0.0      0.11   2.5e+02     268     284 ..     260     276 ..     235     281 .. 0.83
   4 ?   -2.3   0.0      0.76   1.7e+03      25      51 ..     330     356 ..     329     359 .. 0.81

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.25
    Ge1_WD40 189 liveaafspdGtalatasedGevkffq 215
                 +i + a+ p Gt +at s++ +++ + 
  EEA20370.1  40 TIRTLAWNPTGTLIATGSANRTLRIWN 66 
                 666777888888888888887777764 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0029
    Ge1_WD40 186 ehs.liveaafspd.GtalatasedGevkffqvy 217
                  h+  i + +f p   + la +s+dG+v+f+ v 
  EEA20370.1  80 GHTaGIEKVIFNPVrDAELASCSSDGTVRFWDVR 113
                 5543677777777514569************985 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.11
    Ge1_WD40 268 elklWscelWtClqtik 284
                  + lW +  W+C +t+ 
  EEA20370.1 260 LISLWDTTDWVCRRTVS 276
                 57899999999999985 PP

  == domain 4  score: -2.3 bits;  conditional E-value: 0.76
    Ge1_WD40  25 vavhregkylayaikvkntgeglvrvv 51 
                 va h +  +lay++ ++ +  g +r+v
  EEA20370.1 330 VAWHPTRYWLAYSLMAEGSNAGGLRIV 356
                 678888899*****9998777777887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (363 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       327  (0.0182386); expected 358.6 (0.02)
Passed bias filter:                      259  (0.0144459); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.51u 0.32s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 2458.02
//
Query:       EEA20371.1  [L=372]
Description: ribonuclease P protein subunit p40, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      7e-67  225.7   0.0    2.7e-66  223.8   0.0    1.7  2  Ribonuc_P_40  Ribonuclease P 40kDa (Rpp40) subunit


Domain annotation for each model (and alignments):
>> Ribonuc_P_40  Ribonuclease P 40kDa (Rpp40) subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0      0.04   7.1e+02     208     243 ..      33      69 ..      14      73 .. 0.82
   2 !  223.8   0.0   1.5e-70   2.7e-66       2     276 ..      80     342 ..      79     351 .. 0.90

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.04
  Ribonuc_P_40 208 seekvsevtsvswtGlitpeei.selleklrravkes 243
                   +++++s+ + v++t li+pe++ ++ ++++r++++++
    EEA20371.1  33 PFSTISQHVLVHTTELILPEDVyTTTWSSIREKLEKP 69 
                   55666699999999*******9777899999988875 PP

  == domain 2  score: 223.8 bits;  conditional E-value: 1.5e-70
  Ribonuc_P_40   2 eLlekeFiekyikkGsvlalSletridsdnvvallpsGtLtLsldketYerlGLeGkpsrfggrk..kqryvveldLrsksfkhgkkgfeRlrwalk 96 
                   +L+e +F+++++k Gsvl+lS e+r+++d+ + l++ G+LtL++ +e+Ye +GL+Gkp+r+ggrk  k+r+ +e+dLr++s++hgkkgfeR++wa++
    EEA20371.1  80 ALIEGDFFNDFVKPGSVLMLS-EGRPGVDDKFSLSQ-GILTLQMGREKYEHTGLTGKPIRSGGRKhaKERFAIEIDLRQPSMLHGKKGFERIVWACR 174
                   59*******************.**************.***************************99******************************* PP

  Ribonuc_P_40  97 nvlklkfdllfavnpnesskgaedpssklkslkkk.peikecepsiktttlrdvlvPklekdeeeseyseekeledsalellEwLglvslgsertna 192
                   nvl+ ++++l+a+++ +++  ++     ++ l+k  p+i +c  ++    +  v+vP+l++de  s  s    led++++++EwLgl+sl+s+r++ 
    EEA20371.1 175 NVLNASVTWLLACDAVSQNPLDK----AAATLQKYqPRILDCDFEEI--AHPVVNVPPLSMDEARSLSSPA-ALEDYCNDVSEWLGLASLQSPRISV 264
                   ***************66644433....36677777799999999996..688999****998877666555.5************************ PP

  Ribonuc_P_40 193 ddaideylssYelpeseekvs...evtsvswtGlitpeeiselleklr..ravkeskaapWvaltvhGFadspvswkekehgylegGen 276
                   +d id+yls+Y++++se+ +     ++s++w+G +t+ +i++l+ ++   + +++++ ++W al+++ F++++v+            ++
    EEA20371.1 265 EDIIDPYLSRYAVSQSESLQPrstALVSLRWQGAMTSRWINQLFTSCLleQRLHTGRLSAWSALSASTFQRVAVE-----------NSD 342
                   **************999666699**********************98522678899999***************9...........444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (372 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       320  (0.0178482); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2743.86
//
Query:       EEA20372.1  [L=381]
Description: hypothetical protein PMAA_042180 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (381 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       544  (0.0303419); expected 358.6 (0.02)
Passed bias filter:                      271  (0.0151152); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.23s 00:00:00.72 Elapsed: 00:00:00.40
# Mc/sec: 2868.13
//
Query:       EEA20373.1  [L=1670]
Description: DNA replication helicase Dna2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.7e-68  230.4   0.8    4.1e-68  229.2   0.8    1.7  1  Dna2             DNA replication factor Dna2
    9.9e-56  188.5   0.0    2.3e-55  187.3   0.0    1.7  1  AAA_12           AAA domain
    6.9e-32  111.2   2.3    7.5e-16   58.7   0.0    2.9  3  AAA_11           AAA domain
    2.1e-14   53.7   0.0    4.4e-14   52.7   0.0    1.5  1  AAA_30           AAA domain
    1.6e-12   48.0   0.2    5.5e-12   46.2   0.1    2.0  1  AAA_19           AAA domain
    8.5e-10   39.0   0.5    4.1e-08   33.5   0.1    2.6  2  Cas_Cas4         Domain of unknown function DUF83
    8.2e-08   32.5   0.1    1.6e-07   31.5   0.1    1.5  1  PDDEXK_1         PD-(D/E)XK nuclease superfamily
    1.5e-05   24.8   3.2       0.25   11.1   0.1    3.7  3  Viral_helicase1  Viral (Superfamily 1) RNA helicase
    7.6e-05   22.6   0.0    0.00018   21.4   0.0    1.7  1  Helicase_RecD    Helicase
    0.00083   19.0   0.2    0.00083   19.0   0.2    2.8  3  UvrD-helicase    UvrD/REP helicase N-terminal domain
     0.0011   18.6   0.1     0.0022   17.7   0.1    1.5  1  SRP54            SRP54-type protein, GTPase domain
     0.0028   16.9   0.3      0.018   14.2   0.3    2.1  1  PIF1             PIF1-like helicase
     0.0037   17.3   2.1     0.0089   16.1   0.1    2.4  2  ResIII           Type III restriction enzyme, res subunit
     0.0049   17.3   0.0      0.014   15.8   0.0    1.7  1  AAA_16           AAA ATPase domain
     0.0064   16.6   0.1      0.031   14.3   0.1    2.2  1  CbiA             CobQ/CobB/MinD/ParA nucleotide binding domai
  ------ inclusion threshold ------
      0.012   15.2   0.0      0.025   14.2   0.0    1.4  1  cobW             CobW/HypB/UreG, nucleotide-binding domain
      0.026   14.6   0.3       0.11   12.6   0.3    2.0  1  DUF87            Helicase HerA, central domain
      0.032   13.8   0.1      0.075   12.5   0.1    1.5  1  AAA_7            P-loop containing dynein motor region
      0.033   13.7   0.0       0.14   11.7   0.0    1.9  2  AAA_25           AAA domain
      0.041   13.8   0.1      0.096   12.6   0.1    1.6  1  MobB             Molybdopterin guanine dinucleotide synthesis
      0.054   14.0   0.0       0.22   12.1   0.0    2.1  1  AAA_18           AAA domain
      0.059   12.6   0.0       0.12   11.6   0.0    1.5  1  DUF2075          Uncharacterized conserved protein (DUF2075)
      0.066   13.1   0.1       0.16   11.9   0.1    1.6  1  NTPase_1         NTPase
      0.093   13.0   0.3        1.6    9.0   0.0    3.1  2  AAA_22           AAA domain
       0.12   12.1   0.0       0.35   10.6   0.0    1.7  1  RuvB_N           Holliday junction DNA helicase RuvB P-loop d
       0.13   12.2   0.0       0.41   10.6   0.0    1.8  1  AAA_5            AAA domain (dynein-related subfamily)
       0.14   12.5   0.0       0.42   11.0   0.0    1.8  1  AAA              ATPase family associated with various cellul
       0.17   11.8   0.1        0.6   10.0   0.0    2.0  2  UvrD_C_2         UvrD-like helicase C-terminal domain
       0.17   11.6   0.4       0.79    9.4   0.0    2.1  2  IstB_IS21        IstB-like ATP binding protein
       0.17   10.8   0.0       0.35    9.8   0.0    1.4  1  MeaB             Methylmalonyl Co-A mutase-associated GTPase 


Domain annotation for each model (and alignments):
>> Dna2  DNA replication factor Dna2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  229.2   0.8   6.9e-71   4.1e-68       2     203 .]     555     757 ..     554     757 .. 0.99

  Alignments for each domain:
  == domain 1  score: 229.2 bits;  conditional E-value: 6.9e-71
        Dna2   2 ekseekktvvLrddWaetsvekgdiihivgkfe.eekiiidnesnllIlhPdlLvsaTsvanslsClRravLqerlkvsgesskamliGtilHelfqka 99 
                 ek++++k ++Lr++W++++++k+++ih++g+++ ++++i+dn++n++IlhPd+L+saT+va++++C+RravLq+r+k++++ +k+ ++G+ilHe+fq+a
  EEA20373.1 555 EKTHTRKVIILRESWFDSPCTKNSYIHLIGDYDhRGQCIVDNAHNMIILHPDHLISATVVADAITCQRRAVLQDRIKATSDINKPQVYGHILHEVFQEA 653
                 67888999******************************************************************************************* PP

        Dna2 100 lleeeldkekleelldklleknleelyalglteeeakeeikekleeiekwakkyvkksnkakakvekkkekkeklsiskvldiEEniwspkyGLKGkiD 198
                 ++ +++d +++++l++++l +++e+lya++++  ea e +++k++e+++wa+ ++  +++a+  ve+++++k +lsi+k+l++EE++wsp+yGLKG++D
  EEA20373.1 654 MKVNQWDLQSMRTLVERILVQYVESLYAIHVSMIEAVEYVMSKVPELKAWADVFLLPKPNAECMVEDRNGSKANLSINKLLEVEEHVWSPMYGLKGNVD 752
                 *************************************************************************************************** PP

        Dna2 199 atvev 203
                 atv+v
  EEA20373.1 753 ATVQV 757
                 ***97 PP

>> AAA_12  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  187.3   0.0   3.9e-58   2.3e-55       1     198 [.    1294    1520 ..    1294    1521 .. 0.96

  Alignments for each domain:
  == domain 1  score: 187.3 bits;  conditional E-value: 3.9e-58
      AAA_12    1 lerSlferllkkekekvvlLdtqYRmhpeIsrfpsklfYkgkLkdae.svkkrele................................aqealeepl 64  
                  l+ Slf+ l+++++++v+ L++qYRm++eI+ ++++l+Y+g+Lk+++ +v++r+++                                + ++l +p+
  EEA20373.1 1294 LDVSLFKLLCDAQPSSVTNLEHQYRMCEEIMLLSNTLIYSGRLKCGNaEVASRSVKlpklhdsiknhhatslaeitsgrcpgptrarcWLNDLLNPS 1390
                  589*******************************************98888888888999999********************************** PP

      AAA_12   65 eplvfidvekseeekekke..ksyiNeeEaelvvklvekllkkgseeerkkigvitpYraqvellkkklkekeeeksekeievntvdgfQGrekdvi 159 
                  ++++++++++ + ++ ++   ++++N +Ea+l+v+lv++l+++g +   ++igvit+Yr+q+ ll++ l++ ++e     +e++t d+fQGr+k+++
  EEA20373.1 1391 AKTLLVNTDTLSGRAPETLvgSRLTNTSEATLCVQLVQSLISSGISP--REIGVITFYRSQLALLRQSLRQYSNE-----LEMHTTDKFQGRDKEIV 1480
                  ********999999988779899***********************9..*********************77666.....8**************** PP

      AAA_12  160 ilslVRsnekkeig.flkderrlNValTRAkskliivGnk 198 
                  ils+VRsn++k++g +l+d+rr+NVa+TRA++kl+++G+k
  EEA20373.1 1481 ILSCVRSNNDKQVGeLLRDWRRINVAFTRARTKLLVIGSK 1520
                  **************************************97 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.5   0.2   1.9e-16   1.2e-13       2     108 ..    1118    1205 ..    1117    1221 .. 0.94
   2 !   58.7   0.0   1.3e-18   7.5e-16     190     260 ..    1219    1286 ..    1211    1287 .. 0.92
   3 ?   -2.6   0.1       6.4   3.8e+03      49      97 ..    1473    1521 ..    1442    1645 .. 0.59

  Alignments for each domain:
  == domain 1  score: 51.5 bits;  conditional E-value: 1.9e-16
      AAA_11    2 lndsqreaiksalseseitliqGPPGtgKTktivellsqllsrrkseeeksakpriLvCapSNaAvDellerllrglldsegekykpkivRvgneee 98  
                  ln +q++ai +++s ++ +li G PGtgKT+ti++++++l          s+++ +L+++ +++AvD++l+++ +          +++++R+g+ + 
  EEA20373.1 1118 LNIDQKQAIDKVMSAKDYALILGMPGTGKTTTIAHIIRAL---------VSQGKSVLLTSYTHTAVDNILLKIKN---------DNIRTLRLGAVA- 1195
                  899*************************************.........799*********************99.........9***********. PP

      AAA_11   99 riseavksvs 108 
                  +++++v+++ 
  EEA20373.1 1196 KVHPEVQQFV 1205
                  89*9999875 PP

  == domain 2  score: 58.7 bits;  conditional E-value: 1.3e-18
      AAA_11  190 eevldeaeivltTlsgagsklleklakkfdvviIDEAaqavEpstliPlrlgakkvvLvGDpkQLpatvis 260 
                  +e  +e+++v+tT+ g+ ++ +++    fd++i+DEA+q + p +l P r + k ++LvGD+ QLp+ v +
  EEA20373.1 1219 QESYQESKVVATTCLGINHPIFNER--IFDYCIVDEASQITLPVCLGPVRMA-KTFILVGDHYQLPPLVQN 1286
                  4556899******************..8************************.***************976 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 6.4
      AAA_11   49 eeksakpriLvCapSNaAvDellerllr..glldsegekykpkivRvgnee 97  
                  + ++++  iL C  SN+  D+ +  llr  + ++    + + k++ +g+++
  EEA20373.1 1473 QGRDKEIVILSCVRSNN--DKQVGELLRdwRRINVAFTRARTKLLVIGSKS 1521
                  45555666777777775..44444444444446666666666666666666 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.7   0.0   7.3e-17   4.4e-14       2     135 ..    1118    1287 ..    1117    1346 .. 0.78

  Alignments for each domain:
  == domain 1  score: 52.7 bits;  conditional E-value: 7.3e-17
      AAA_30    2 lnaeQaaavealltsgdrvavltGpAGtGKttalkalreaweaaggrviglAptgkaAkvLa...........................eelgieas 71  
                  ln +Q++a++++++ +d +a++ G +GtGKtt+++++ +a+ ++g++v++ + t++a +++                            + + i+ +
  EEA20373.1 1118 LNIDQKQAIDKVMSAKD-YALILGMPGTGKTTTIAHIIRALVSQGKSVLLTSYTHTAVDNILlkikndnirtlrlgavakvhpevqqfvDLAAIPKN 1213
                  7899*********9998.******************************************6645777766666666666665555544434456777 PP

      AAA_30   72 tiakllkrlk..............grarlepg..tllivDEagmvdtkqlaallkaaekagakvilvGDerQlasVeaGg 135 
                  ti++l ++++                  ++++  +  ivDEa+ +        ++ a++     ilvGD+ Ql++  + +
  EEA20373.1 1214 TIEELQESYQeskvvattclginhP--IFNERifDYCIVDEASQITLPVCLGPVRMAKT----FILVGDHYQLPPLVQNK 1287
                  77777777779**********9762..3334447*********************9988....**********9865543 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.2   0.1   9.2e-15   5.5e-12       1     143 [.    1122    1282 ..    1122    1285 .. 0.70

  Alignments for each domain:
  == domain 1  score: 46.2 bits;  conditional E-value: 9.2e-15
      AAA_19    1 qreav.e.alkekvllvtaGpGtGKTrvlkhivallvelggvkpeeillvaftgrAakelrerlaalgaeatTiHrlal.................. 77  
                  q++a+ +  ++++  l+++ pGtGKT+++ hi++ lv++g    +++ll ++t+ A++++  ++   + +++T+   a+                  
  EEA20373.1 1122 QKQAIdKvMSAKDYALILGMPGTGKTTTIAHIIRALVSQG----KSVLLTSYTHTAVDNILLKI--KNDNIRTLRLGAVakvhpevqqfvdlaaipk 1212
                  78899557788999**************************....89**************9888..4556666653333556666666644444444 PP

      AAA_19   78 .......ldfddlltealelle...eaeeekklqeee.llivDEfqdvd.elqyrLlkallgekkklllvGDpdQliy 143 
                           +++ +  a + l        ++ +   + + ivDE+++++ ++    ++  +    +++lvGD+ Ql++
  EEA20373.1 1213 ntieelqESYQESKVVATTCLGinhP-IFNERI---FdYCIVDEASQITlPVCLGPVRMAK----TFILVGDHYQLPP 1282
                  44433333333333334444434321.222222...4699*********999887777666....5**********97 PP

>> Cas_Cas4  Domain of unknown function DUF83
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.1      0.17     1e+02       5      44 ..     614     653 ..     610     689 .. 0.77
   2 !   33.5   0.1   6.8e-11   4.1e-08      64     161 ..     766     867 ..     748     868 .. 0.81

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.17
    Cas_Cas4   5 iqyyliCkrklwlish.eitleensetvelGkllheesyer 44 
                 +   + C+r++ l  + + t + n+ +v+ G +lhe  +e 
  EEA20373.1 614 VADAITCQRRAVLQDRiKATSDINKPQVY-GHILHEVFQEA 653
                 667789********998999999999999.******44443 PP

  == domain 2  score: 33.5 bits;  conditional E-value: 6.8e-11
    Cas_Cas4  64 keklvvvEvKkskkkeeaa.klQllyYlllLe.kkgveikeGvleypkekkreevelteelreelekaikeieeiisse..kppkvkkkkiCkkCayae 158
                 k+ +++ E+K +kk++  + ++Q   Y llL  + ++e++ G l+y++ kk+ +++  +++  ++ +  +++  +i+++   pp  ++k++C++C  + 
  EEA20373.1 766 KTLTIPLEMKTGKKDTSHShRAQTSLYTLLLSdRYDIEVTFGLLYYLEMKKMFRIRGIRHELLQMIQERNRLAGFIREKmeLPPMIQRKHLCNQCYSKT 864
                 4556789*******987766************9**********************965555555555555666666555457999999*******9999 PP

    Cas_Cas4 159 lCl 161
                  C+
  EEA20373.1 865 ACF 867
                 998 PP

>> PDDEXK_1  PD-(D/E)XK nuclease superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.5   0.1   2.7e-10   1.6e-07       2     254 ..     609     866 ..     608     867 .. 0.58

  Alignments for each domain:
  == domain 1  score: 31.5 bits;  conditional E-value: 2.7e-10
    PDDEXK_1   2 lSvsrletfleCplrfflryllglreeeeleap.dlGtlvHaaleefye...wkkldke.dleelleeaveelwpellleeei.........lessarl 86 
                 +S++ + +  +C +r  l+  +++++++++++p  +G+++H++++e  +   w+  + +   e++l ++ve l      + ++         +++ ++l
  EEA20373.1 609 ISATVVADAITCQRRAVLQ--DRIKATSDINKPqVYGHILHEVFQEAMKvnqWDLQSMRtLVERILVQYVESLY-----AIHVsmieaveyvMSKVPEL 700
                 6999999***********7..666669*****99***************5553222222233333323333222.....22222222222224444444 PP

    PDDEXK_1  87 rylaekl...kevleklve.rlaeeleakrg.frpvalelefg...gekvrLkGriDr.vd....dkeg...elri.iDyKtgsappkskelaelkegl 168
                 + +a+     k  +e +ve r     +a+ +  + +++e       +  + LkG +D  v+    d +g   +l+i ++ Ktg+   k+++    +++ 
  EEA20373.1 701 KAWADVFllpKPNAECMVEdRNGS--KANLSiNKLLEVE---EhvwSPMYGLKGNVDAtVQvvynD-GGdqkTLTIpLEMKTGK---KDTS---HSHRA 787
                 444444434444444444434444..3333344555555...044413344*******76699743.33588555559******...5554...45889 PP

    PDDEXK_1 169 QlllYllalaegeelkeegepagalylrleepkvkdeevvkkmalteeeleallqeleelaeeilag.efparpskk..CeyCpyksvC 254
                 Q+ lY l+l     +  e    g+ly+   +++ + +++       + el ++ qe ++la  i+++ e p++  +k  C++C  k  C
  EEA20373.1 788 QTSLYTLLLSDR--YDIE-VTFGLLYYLEMKKMFRIRGI-------RHELLQMIQERNRLAGFIREKmELPPMIQRKhlCNQCYSKTAC 866
                 **********99..4422.37888877763333333333.......445555555555555555544455555555559*******999 PP

>> Viral_helicase1  Viral (Superfamily 1) RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.1   0.1   0.00041      0.25       2      48 ..    1137    1187 ..    1136    1206 .. 0.65
   2 ?    5.5   0.0      0.02        12      59     107 ..    1241    1287 ..    1193    1305 .. 0.72
   3 ?    6.4   0.1     0.011       6.4     167     233 ..    1440    1517 ..    1394    1518 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00041
  Viral_helicase1    2 vvhGvpGcGKStlirkllrtsliltvnrptaelltegk.......pklpnlsvr 48  
                       ++ G+pG GK+t i +++r    ++++++ + l +  +        k +n+++r
       EEA20373.1 1137 LILGMPGTGKTTTIAHIIRA--LVSQGKS-VLLTSYTHtavdnilLKIKNDNIR 1187
                       689****************9..5445444.322222223344333444444444 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.02
  Viral_helicase1   59 kstkgkililDEylllhaGyill.laalskaklvilfGDplQipfhsrna 107 
                       ++  ++++i+DE+ + +   + + l     ak++il+GD++Q p   +n+
       EEA20373.1 1241 NERIFDYCIVDEASQIT---LPVcLGPVRMAKTFILVGDHYQLPPLVQNK 1287
                       34568999*****9988...666344568899**********99766555 PP

  == domain 3  score: 6.4 bits;  conditional E-value: 0.011
  Viral_helicase1  167 lvyltftqalkealgvr........evttvhevqGltfdkVtlvllketdlelis...esrenllvAlTRhrkslvil 233 
                       + ++tf ++ ++ l+++        e++t+   qG   + V+l + ++++++ +    ++     vA+TR+r++l+++
       EEA20373.1 1440 IGVITFYRSQLALLRQSlrqysnelEMHTTDKFQGRDKEIVILSCVRSNNDKQVGellRDWRRINVAFTRARTKLLVI 1517
                       444555555555444445557888999*************999666554444233578778999**********9876 PP

>> Helicase_RecD  Helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0     3e-07   0.00018       2     109 ..    1138    1263 ..    1137    1275 .. 0.64

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 3e-07
  Helicase_RecD    2 ltAdRGRGKSaalGlalaaliaegksnilvtapskenvktlfefl.akglealglke.............eekkkkaekaelrvr...kqriey 78  
                     + + +G+GK+++++ ++ al+++gk ++l+t+ ++++v++++  + + ++++l+l                                 k++ie 
     EEA20373.1 1138 ILGMPGTGKTTTIAHIIRALVSQGK-SVLLTSYTHTAVDNILLKIkNDNIRTLRLGAvakvhpevqqfvdL-------------AaipKNTIEE 1217
                     77889******************98.8***********998766614567777777655554444333330.............2223222222 PP

  Helicase_RecD   79 iapdellklkeqa....................dllvvDEAAaiplpllkk 109 
                     ++ +        +                    d  +vDEA++i lp+   
     EEA20373.1 1218 LQESYQE-----SkvvattclginhpifnerifDYCIVDEASQITLPVCLG 1263
                     2111111.....112223334455666777778*************98655 PP

>> UvrD-helicase  UvrD/REP helicase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.5      0.79   4.7e+02     127     169 ..     429     514 ..     344     591 .. 0.67
   2 !   19.0   0.2   1.4e-06   0.00083       2      68 ..    1119    1190 ..    1118    1230 .. 0.77
   3 ?   -1.7   0.0       2.6   1.6e+03      32      72 ..    1425    1464 ..    1420    1483 .. 0.71

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.79
                    H...HCCHHHHHHHHHSCHSHTTTTHHHHHHHHHHHHHHCCCCCH........................................H CS
  UvrD-helicase 127 e...dlkqqellkelleksaddslnldkkkleklikelsksrnik........................................k 169
                    e   d++  e ++ell+++++++  ++k+ l++ +++ls ++++                                          
     EEA20373.1 429 EfddDVEFGEGMEELLTQYEKQTPAIQKQTLSQPSRDLSYEQPMMgvqpntvtrnagisvenslsddefddndldldnvlqelehQ 514
                    13447778889999999999999999999999999999999988776666665555555555444444333333333332222220 PP

  == domain 2  score: 19.0 bits;  conditional E-value: 1.4e-06
                     SHHHHHHHHS...-SSEEEEEE-TTSSHHHHHHHHHHHHHHTSSSTGGGEEEEESSHHHHHHHHHHHHH......H CS
  UvrD-helicase    2 npeqreaias...lggpilveAsAGsGKTfvlaerilrlikeeeiepdrilvvTFTnkAaeElkeRiee......a 68  
                     n +q++ai +    +   l++  +G+GKT+++a+ i  l+ ++    +++l+  +T  A + +  +i++      +
     EEA20373.1 1119 NIDQKQAIDKvmsAKDYALILGMPGTGKTTTIAHIIRALVSQG----KSVLLTSYTHTAVDNILLKIKNdnirtlR 1190
                     557777777655367789*************************....9*************999999985555550 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 2.6
                     HHHHHHHHTSSSTGGGEEEEESSHHHHHHHHHHHHHHHHHC CS
  UvrD-helicase   32 erilrlikeeeiepdrilvvTFTnkAaeElkeRieealkka 72  
                     +++  li  + i+p++i v+TF +   + l++ +++  ++ 
     EEA20373.1 1425 QLVQSLISSG-ISPREIGVITFYRSQLALLRQSLRQYSNEL 1464
                     4555566666.***********8777777777776655554 PP

>> SRP54  SRP54-type protein, GTPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.1   3.6e-06    0.0022       3      36 ..    1135    1168 ..    1133    1219 .. 0.92

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 3.6e-06
                  EEEEEESTTSSHHHHHHHHHHHHHHTTS-EEEEE CS
       SRP54    3 villvGlqGaGKTttlaKLaallkkegkkvllva 36  
                  + l++G+ G+GKTtt+a + + l ++gk+vll +
  EEA20373.1 1135 YALILGMPGTGKTTTIAHIIRALVSQGKSVLLTS 1168
                  5799***************************986 PP

>> PIF1  PIF1-like helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.3     3e-05     0.018       2      66 ..    1118    1177 ..    1117    1319 .. 0.60

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 3e-05
                  --HHHHHHHHHH......HCTS-EEEEESTTSSCHHHHHHHHHHCHCTCCCEEEEESSHHHHHCC CS
        PIF1    2 LneeQkkvfdaiieavlnekgklfFvtGsgGtgKtflwkallkklrsegkivlavAssGvAalll 66  
                  Ln +Qk+++d+++     +      + G+ GtgKt    +++ +l s+gk vl +  +  A  ++
  EEA20373.1 1118 LNIDQKQAIDKVM-----SAKDYALILGMPGTGKTTTIAHIIRALVSQGKSVLLTSYTHTAVDNI 1177
                  8999***999993.....334556688****************************9987775333 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.2       1.6   9.7e+02      87     144 ..     542     600 ..     508     622 .. 0.71
   2 !   16.1   0.1   1.5e-05    0.0089       4      84 ..    1118    1204 ..    1115    1256 .. 0.60

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 1.6
                 EEESSS-B--............-SEEEEEHHHHHHTH........HHHTTT-SEEEEETGGGT CS
      ResIII  87 kkvsgdkkka.....kekdstnkkilvttiqsldadseeeeeeseellrdrfdviiiDEaHrl 144
                 ++++     +     + ++++++k+++  ++ +d++ +++++ +   + d+    i+D aH++
  EEA20373.1 542 GFKQP----EqvlsvTDEKTHTRKVIILRESWFDSPCTKNSYIHLIGDYDHRGQCIVDNAHNM 600
                 22333....2333466677889999999999999999777777777777888899******86 PP

  == domain 2  score: 16.1 bits;  conditional E-value: 1.5e-05
                  E-HHHHHHHHHHT......TTSEEEEEESTTSTHHHHHHHHHHHH-S................-EEEEESSHHHHHHHHHHGGGGTGG.... CS
      ResIII    4 lreyQeeaienlleklkskrdkrglikmaTGtGKTlvaaklierllkkgkee...........kflflvprkslleqtleefkkflseayke 84  
                  l+  Q++ai+++++     +d  +++ m  GtGKT ++a++i++l ++gk             ++l+ + + ++    l +++k+ +e +++
  EEA20373.1 1118 LNIDQKQAIDKVMS----AKDYALILGM-PGTGKTTTIAHIIRALVSQGKSVlltsythtavdNILLKIKNDNIRTLRLGAVAKVHPEVQQF 1204
                  66679999999982....4556666666.5*****************988546666665555555555555555555555555555555555 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   2.3e-05     0.014      25      85 ..    1134    1189 ..    1123    1242 .. 0.67

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 2.3e-05
      AAA_16   25 elvllsGesGvGKsslvrellralekdg.giflrgkcdqlesaipysalaqalareellrql 85  
                   + l+ G++G+GK++ + ++ ral  +g  ++l+  ++        + ++  +++ + +r l
  EEA20373.1 1134 DYALILGMPGTGKTTTIAHIIRALVSQGkSVLLTSYTHTA-----VDNILLKIKN-DNIRTL 1189
                  6789*****************9999885333333222222.....2335555533.444444 PP

>> CbiA  CobQ/CobB/MinD/ParA nucleotide binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.1   5.2e-05     0.031       9      32 ..    1143    1166 ..    1136    1234 .. 0.93

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 5.2e-05
                  TSSHHHHHHHHHHHHHHTT--EEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxx RF
        CbiA    9 GvGKTtlaanLaralarrglrVll 32  
                  G+GKTt+ a+++ral  +g+ Vll
  EEA20373.1 1143 GTGKTTTIAHIIRALVSQGKSVLL 1166
                  9*********************98 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   4.2e-05     0.025       4      62 ..    1137    1195 ..    1135    1256 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 4.2e-05
                  EEEESTTCCHHHHHHHHHCT--SS-EEEEESS-SSCHCCCCCCHCCCT.EEEETTTTEC CS
        cobW    4 vltGflGsGKTtLlnhllenraglklavivNefgevsiDaellretgveivelenGciC 62  
                  ++ G +G+GKTt + h+++   ++   v++  + ++++D+ ll+ ++++i +l  G + 
  EEA20373.1 1137 LILGMPGTGKTTTIAHIIRALVSQGKSVLLTSYTHTAVDNILLKIKNDNIRTLRLGAVA 1195
                  688***************99999********************9999999999988775 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.3   0.00018      0.11      27      57 ..    1137    1166 ..    1126    1167 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 0.00018
       DUF87   27 AilgsTGsGKSntvavLleellekkgatili 57  
                  +ilg+ G+GK++t+a +++ l+ ++g ++l+
  EEA20373.1 1137 LILGMPGTGKTTTIAHIIRALV-SQGKSVLL 1166
                  69********************.77777775 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.1   0.00013     0.075      22      64 ..    1122    1164 ..    1116    1191 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00013
       AAA_7   22 ysyllelllknkkpvllvGptGtGKtviikdllkkldkekyls 64  
                  ++  +++++++k   l+ G  GtGKt++i +++++l ++  ++
  EEA20373.1 1122 QKQAIDKVMSAKDYALILGMPGTGKTTTIAHIIRALVSQGKSV 1164
                  56678999***********************999998554444 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00024      0.14      22      66 ..    1122    1168 ..    1104    1215 .. 0.81
   2 ?   -1.8   0.0       3.3     2e+03     159     178 ..    1487    1506 ..    1466    1529 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00024
      AAA_25   22 rrwlvkgllpagelallaGapgtGKttlaldlalava.tGkpwlg.p 66  
                  +++ ++ ++ a++ al+ G pgtGKtt   ++  a++ +Gk++l  +
  EEA20373.1 1122 QKQAIDKVMSAKDYALILGMPGTGKTTTIAHIIRALVsQGKSVLLtS 1168
                  56789999**************************9999999887754 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 3.3
      AAA_25  159 ensnsdvgalvealeriarr 178 
                  +n++++vg+l+ +++ri  +
  EEA20373.1 1487 SNNDKQVGELLRDWRRINVA 1506
                  45555666666666665332 PP

>> MobB  Molybdopterin guanine dinucleotide synthesis protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.1   0.00016     0.096       4      60 ..    1138    1196 ..    1136    1228 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 0.00016
        MobB    4 ivgksgsGKTtLleklipelkarglrvgtiKhahhgfd..vdkpgkDsyrhrkAGAkev 60  
                  i g+ g+GKTt + ++i++l ++g +v +   +h ++d  + k   D  r  + GA + 
  EEA20373.1 1138 ILGMPGTGKTTTIAHIIRALVSQGKSVLLTSYTHTAVDniLLKIKNDNIRTLRLGAVAK 1196
                  78999**********************99999999988767888889999888888765 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   0.00037      0.22       2      62 ..    1137    1199 ..    1137    1245 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00037
      AAA_18    2 lltGtpGvGKttlakeLskrlgfgvnlrdvakenglllevdpe....aldeskrldedkldklld 62  
                  l+ G+pG+GKtt   ++ + l  + + ++v+  +++ + vd+     + d+ + l+ + ++k++ 
  EEA20373.1 1137 LILGMPGTGKTTTIAHIIRAL--VSQGKSVLLTSYTHTAVDNIllkiKNDNIRTLRLGAVAKVHP 1199
                  689********9999998888..999999999999999999998777666666666666666655 PP

>> DUF2075  Uncharacterized conserved protein (DUF2075)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0    0.0002      0.12       3      66 ..    1135    1196 ..    1133    1256 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.0002
     DUF2075    3 vvlVtGvaGtGKtvvllnllaeleddeeertavylsvNhplvlvlrealakke....ekkkkkeafek 66  
                    l+ G +GtGKt    +++ +l   ++++++ + s  h  v+ +  ++++++    +      a++k
  EEA20373.1 1135 YALILGMPGTGKTTTIAHIIRAL--VSQGKSVLLTSYTHTAVDNILLKIKNDNirtlR----LGAVAK 1196
                  57899******************..999999999999999999999999999954431....222222 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.1   0.00026      0.16       4      30 ..    1138    1164 ..    1135    1169 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00026
                  EE--TTSSHHHHHHHHHHHH...GGGE CS
    NTPase_1    4 iTGppGvGKtTlvkkvlellkssgvkv 30  
                  i G+pG+GKtT +  ++++l s+g +v
  EEA20373.1 1138 ILGMPGTGKTTTIAHIIRALVSQGKSV 1164
                  77********************99876 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.1       2.7   1.6e+03      80     106 ..     581     605 ..     505     627 .. 0.62
   2 ?    9.0   0.0    0.0027       1.6       8      32 ..    1136    1160 ..    1130    1205 .. 0.82

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 2.7
      AAA_22  80 ealeqalraravielliiDEaqhlr..se 106
                 +++ ++ ++ +     i+D+a++++  ++
  EEA20373.1 581 HLIGDYDHRGQ----CIVDNAHNMIilHP 605
                 44444444444....499****9865643 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.0027
      AAA_22    8 lvvtGesGtGKTtllrrlleqldee 32  
                   ++ G +GtGKTt+++ + + l+ +
  EEA20373.1 1136 ALILGMPGTGKTTTIAHIIRALVSQ 1160
                  6899*************99999765 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00058      0.35      18      55 ..    1117    1156 ..    1110    1186 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00058
      RuvB_N   18 klkifieaa.kkreealdhvllyGpPGlGkt.tlakiiak 55  
                  +l+i  + a  k  +a d+ l+ G PG Gkt t+a+ii +
  EEA20373.1 1117 NLNIDQKQAiDKVMSAKDYALILGMPGTGKTtTIAHIIRA 1156
                  56665544414556889*************7358999865 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00069      0.41       3      37 ..    1137    1171 ..    1136    1218 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00069
                  EEE--SSSSHHHHHHHGGGGB..S--EEEEE--TT-- CS
       AAA_5    3 lLvGppGtgKselaerlaaal..nreveyvqltrdtt 37  
                  l++G pGtgK++ + ++ +al  +     v+lt++t 
  EEA20373.1 1137 LILGMPGTGKTTTIAHIIRALvsQ--GKSVLLTSYTH 1171
                  789******************554..44444444443 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0    0.0007      0.42       2      23 ..    1137    1158 ..    1136    1206 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.0007
                  EEESSTTSSHHHHHHHHHHHHT CS
         AAA    2 llyGppGtGKTllakavakelg 23  
                  l+ G pGtGKT+++  +++ l 
  EEA20373.1 1137 LILGMPGTGKTTTIAHIIRALV 1158
                  789***********99999873 PP

>> UvrD_C_2  UvrD-like helicase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       9.8   5.9e+03      43      49 ..    1377    1383 ..    1376    1384 .. 0.91
   2 ?   10.0   0.0     0.001       0.6       6      52 .]    1468    1517 ..    1466    1517 .. 0.75

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 9.8
    UvrD_C_2   43 TRArekl 49  
                  TRAr +l
  EEA20373.1 1377 TRARCWL 1383
                  9*****9 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.001
    UvrD_C_2    6 tihkaQGsefpaVivfdpdlaaarmgel.....rrrlLYtavTRAreklilv 52  
                  t  k+QG   ++Vi+  +   + ++  +       r + +a+TRAr+kl ++
  EEA20373.1 1468 TTDKFQGRDKEIVILSCVRSNNDKQ--VgellrDWRRINVAFTRARTKLLVI 1517
                  6679999999999996665333333..244689788889**********985 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.1       2.1   1.2e+03      86     145 ..     504     564 ..     502     571 .. 0.78
   2 ?    9.4   0.0    0.0013      0.79      41      84 ..    1127    1170 ..    1096    1196 .. 0.79

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 2.1
   IstB_IS21  86 LveelkrarrdgklaralkrllkvdllilDdlgllpldq.aeaellfeviekryerrsiii 145
                 L + l+  +++ +  ra++++ +  ++ + +  + +l+  ++ e+++ v +++  +r +ii
  EEA20373.1 504 LDNVLQELEHQSEKPRAQQAIKRYLIVQIAESTYDTLKGfKQPEQVLSVTDEKTHTRKVII 564
                 5566777777777788888888888888999999999864678999999999998888887 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.0013
   IstB_IS21   41 lsfiekkenivllGpsGvGKshlaialgveavraglsvlfvrve 84  
                  ++ +++k+  ++lG +G+GK+   + + ++ v +g+svl ++ +
  EEA20373.1 1127 DKVMSAKDYALILGMPGTGKTTTIAHIIRALVSQGKSVLLTSYT 1170
                  45567888999***********9999************988754 PP

>> MeaB  Methylmalonyl Co-A mutase-associated GTPase MeaB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0   0.00059      0.35      34      60 ..    1138    1164 ..    1113    1173 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00059
                  EEE-TTSSHHHHHHHHHHHHHCTT--E CS
        MeaB   34 ltGvPGaGkstlvealglelrrrGkrv 60  
                  + G+PG+Gk t++ +++  l+++Gk v
  EEA20373.1 1138 ILGMPGTGKTTTIAHIIRALVSQGKSV 1164
                  4589********************988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1670 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       969  (0.0540465); expected 358.6 (0.02)
Passed bias filter:                      660  (0.0368119); expected 358.6 (0.02)
Passed Vit filter:                        84  (0.00468515); expected 17.9 (0.001)
Passed Fwd filter:                        30  (0.00167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              30  [number of targets reported over threshold]
# CPU time: 1.14u 0.30s 00:00:01.44 Elapsed: 00:00:00.50
# Mc/sec: 9962.12
//
Query:       EEA20374.1  [L=113]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-21   75.1   0.0    5.4e-21   74.8   0.0    1.2  1  ESSS      ESSS subunit of NADH:ubiquinone oxidoreductase (com


Domain annotation for each model (and alignments):
>> ESSS  ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.8   0.0     3e-25   5.4e-21      36     104 ..      33     110 ..       6     111 .. 0.89

  Alignments for each domain:
  == domain 1  score: 74.8 bits;  conditional E-value: 3e-25
        ESSS  36 dshGfdkd.pve...........dkenmeavfffgvsivlVlgsvfvaYlpdtsiqeWArrEAerllkrREaeglpileen 104
                   hG+++d p++            ke++e++++fg++++lV+++v+++++pdtsiq+WA +EA+r+l   Eaeg+    e+
  EEA20374.1  33 ADHGNHYDpPSGwlfgvkpgekyVKEGWENIWYFGFIGSLVAAGVAYVFKPDTSIQTWALEEARRRL---EAEGILEDPEK 110
                 46999999777799999999999********************************************...*****988776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (113 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       383  (0.021362); expected 358.6 (0.02)
Passed bias filter:                      346  (0.0192983); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.30s 00:00:00.71 Elapsed: 00:00:00.46
# Mc/sec: 743.84
//
Query:       EEA20375.1  [L=275]
Description: nitrilase, putitive [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.3e-58  195.6   0.1      1e-57  195.4   0.1    1.0  1  CN_hydrolase     Carbon-nitrogen hydrolase
  ------ inclusion threshold ------
       0.84   10.1   2.3         27    5.3   0.0    2.8  3  Clathrin_propel  Clathrin propeller repeat


Domain annotation for each model (and alignments):
>> CN_hydrolase  Carbon-nitrogen hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  195.4   0.1   1.2e-61     1e-57       1     261 []       3     261 ..       3     261 .. 0.95

  Alignments for each domain:
  == domain 1  score: 195.4 bits;  conditional E-value: 1.2e-61
                   EEEEEEBB-STTHHHHHHHHHHHHHHHHHHTTESEEEEETTTTTBSSSHHHHHHHHB.HSSSHHHHHHHHHHHHHTEEEEEEEEEEECCTTEEEEEE CS
  CN_hydrolase   1 rvAvvQlpqkaadleanlqklleliaeAarkgadLivlPElfitgykeeahfleaAe.aglgetlallaalarkngiavvigliereltngklqayn 96 
                   ++A+ Ql++ +a+ ++nl+++++li++A   ga+ ++lPE+ +++ +++a+ + +     ++e++ +l++ a++ +  + +g+ e   ++g ++  n
    EEA20375.1   3 KIAIGQLCS-TASMAHNLAQCQTLITKAIAAGAKALFLPEATDYIASSSAESVSLVRsVQQSEFVLGLQKEAKNAKFPINVGIHEP--AQGGIKVKN 96 
                   69*******.79********************************99888888876668889*************************..7888888** PP

                   EEEEEETTSEEEEEEE-SS--E.ECTTSCECCGHHTSCS-SS.S-EEEETTEEEEEEEGGGGGSHHHHHHHHHTT-SEEEEBH.GCCCTCHHHHHHH CS
  CN_hydrolase  97 tavlldldgklvgkyrKlhLfp.geprpptaverelfepgdg.ipvfdtpvgkiGaaiCyeigfpellralalkgaeilvnlserapvpksmgppqw 191
                   t +++d+ g++v++y+K+hLf+ ++ ++p   e+  +e+g++ +p+f+tpvg++G+aiC + +fpe+++al++++a+i+++    + +++ +g+++w
    EEA20375.1  97 TLIWIDEHGEIVQRYQKIHLFDvEIKDGPVLKESASVEAGTQiLPPFETPVGRVGLAICFDLRFPEISIALKRQNAQIITFP---SAFTVPTGQEHW 190
                   *******************************************************************************993...478899****** PP

                   HHHHHHHHHHHTSEEEEEEBEEEHCETTEEEE--EEEE-TTS-EEEEC..CSSSTEEEEEEEEHHHHHHHHH CS
  CN_hydrolase 192 ellgraralengcfviaanqvggyeqlilwpvghSaiidpdGrilagl..geeeegvliaeidladvratrr 261
                   e+l rara+e++ +viaa+qvg+ +++++ ++ghS+i+dp+G+++a+l  + +e ++++a+id++++ ++rr
    EEA20375.1 191 EALLRARAIETQSYVIAAAQVGA-HNEKRTSYGHSMIVDPWGQVVAKLggDFKEPEIATADIDFDLIDKIRR 261
                   ***********************.***********************985667778*********9998875 PP

>> Clathrin_propel  Clathrin propeller repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.003        27      26      37 .]     109     120 ..      94     120 .. 0.89
   2 ?    3.8   0.1    0.0088        79       3      16 ..     171     184 ..     170     187 .. 0.83
   3 ?   -3.6   0.1       1.9   1.7e+04       3      10 ..     247     254 ..     246     254 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.003
                      ETEEEEEEEETT CS
  Clathrin_propel  26 tkkGqvqlysve 37 
                      +++++++l++ve
       EEA20375.1 109 QRYQKIHLFDVE 120
                      799********8 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.0088
                      TCEEEECCCEEEEE CS
  Clathrin_propel   3 nsqiinfptatnes 16 
                      n+qii+fp+a  ++
       EEA20375.1 171 NAQIITFPSAFTVP 184
                      89*******97666 PP

  == domain 3  score: -3.6 bits;  conditional E-value: 1.9
                      TCEEEECC CS
  Clathrin_propel   3 nsqiinfp 10 
                       +++i+f+
       EEA20375.1 247 ATADIDFD 254
                      6899*996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       351  (0.0195772); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.43
# Mc/sec: 1914.34
//
Query:       EEA20376.1  [L=1025]
Description: exosome complex exonuclease exoribonuclease (Rrp44), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.6e-98  328.6   0.0    6.9e-98  328.0   0.0    1.3  1  RNB         RNB domain
    6.5e-33  113.5   0.2      2e-32  111.9   0.2    1.9  1  Rrp44_CSD1  Rrp44-like cold shock domain
    7.5e-28   96.3   0.3    2.3e-27   94.8   0.3    1.9  1  Rrp44_S1    S1 domain
    6.1e-21   74.2   0.0    2.9e-20   72.1   0.0    2.2  2  OB_Dis3     Dis3-like cold-shock domain 2 (CSD2)
    1.8e-11   44.5   0.1    4.3e-11   43.2   0.1    1.7  1  PIN_4       PIN domain
    1.7e-09   37.7   0.0    1.3e-05   25.2   0.0    2.8  2  CSD2        Cold shock domain


Domain annotation for each model (and alignments):
>> RNB  RNB domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  328.0   0.0  2.3e-101   6.9e-98       1     324 [.     513     845 ..     513     847 .. 0.94

  Alignments for each domain:
  == domain 1  score: 328.0 bits;  conditional E-value: 2.3e-101
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         RNB   1 RkdlrdllvitIdpedakdlDdAisieklpngnyelgVhIADvshyvkegspldkearkratsvyLpekvvpMLPqelsedlcSLnpgedrlalsvlid 99 
                 R+dlrdllv++Idp++++d+DdA++ + lpngnye+gVhIADvs +vk+++++d ea +r+t+vyL +k + MLP  l +dlcSL+p+ +r a+s +++
  EEA20376.1 513 RRDLRDLLVCSIDPPGCQDIDDALHARLLPNGNYEVGVHIADVSNFVKPNNAMDLEASLRGTTVYLVDKRIDMLPMLLGTDLCSLKPYVERFAFSTIWE 611
                 9************************************************************************************************** PP

                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxx RF
         RNB 100 vdekgevlsveiylsvIkskarltydevqdlleqkdekeekktaedLellyelakalrkkRlkkgalefdspeikllldedkgnrie.lkveeetkahs 197
                 +  +ge+ s ++++svI s++ ++y+++q  ++++ +   ++ ++++++l +++k+lr+kR + gal++ spei+++ +++ + +++ +k++ +   +s
  EEA20376.1 612 ITPNGEIVSSDFTKSVILSREAFSYEQAQLRIDDASQ--TDDLTQSMRTLLHFSKILRQKRMDAGALNLASPEIRIETESELNDPLTdVKTKAHLATNS 708
                 ********************************87776..568***********************************9986555554277777777*** PP

                 xxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxx.. RF
         RNB 198 lveelmllANelvArfl.seleipailriheepsnekledliklakklglklednsskknlqeslekleeee...aeqllselllrllkeakyssep.. 290
                 lvee+mllAN +vA+++ s+++++a+lr+h  p ++++e+l+  ++k    + d ss  +l +sl+++ + +    ++l++ l +r++++a+y++    
  EEA20376.1 709 LVEEFMLLANITVASKIySAFPQTALLRRHASPPPQNFEQLAAQLQKKRGLHLDVSSSGALADSLDRCVDPKnpfFNTLVRILATRCMTSAEYFTAGah 807
                 ****************************************9988884444456677777**********99999999*****************88899 PP

                 ....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         RNB 291 ....vgHfgLaleeYthfTSPirRYpDlvvhrllkall 324
                     ++H+gLa ++YthfTSPirRY+Dl+vhr+l a++
  EEA20376.1 808 aeaeFRHYGLASPIYTHFTSPIRRYADLIVHRQLAAAI 845
                 9999******************************9875 PP

>> Rrp44_CSD1  Rrp44-like cold shock domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.9   0.2   6.8e-36     2e-32       2     147 ..     247     384 ..     246     385 .. 0.82

  Alignments for each domain:
  == domain 1  score: 111.9 bits;  conditional E-value: 6.8e-36
                 S-------HHHHHHHHHTTSEEEEEEEEESSBTTEEEEE-SSSSS-EEEESHHHHTS--TT-EEEEEE--GGG-B---SS-B-CCCSSTT--TT-B--S CS
  Rrp44_CSD1   2 ftfpeyystarvmgglkngvlyqgniqiseynflegsvslprfskpvlivgqknlnrafngdqvivellpqsewkapssivldsehfdvndnpdieagd 100
                 f +peyys +++m g++ g ++qg  +is yn+legsv +p f kp+li+g+ n nra+ gd v+ve+lp+ +wk+pss ++d e +  n+npdie  +
  EEA20376.1 247 FFYPEYYSMSKMMTGVRAGTMHQGIFNISPYNYLEGSVNVPAFEKPLLILGRDNSNRAVSGDIVVVEVLPKDQWKSPSSKIIDEEAVTKNENPDIEETE 345
                 89*********************************************************************************************9765 PP

                 SS--SSSSS-SS--SHHHHHHHH...HHHHHHHHHSSSB-BEEEEEEEE- CS
  Rrp44_CSD1 101 dddnnesssnttvisdkqrrlla...kdamiaqrskkiqptakvvyiqrr 147
                    n           ++++r l    k a   +   k qpta++v i +r
  EEA20376.1 346 VIVN-----------EREKRALQeevKKAHGKNAEGKAQPTARIVGIVKR 384
                 4333...........23333332000223333345577777777766655 PP

>> Rrp44_S1  S1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.8   0.3   7.7e-31   2.3e-27       2      88 ..     909    1018 ..     908    1019 .. 0.91

  Alignments for each domain:
  == domain 1  score: 94.8 bits;  conditional E-value: 7.7e-31
                  EEEEEEEEEESSEEEEEETTTTEEEEEEHHHCBS-GGG...................-EEETTTTEEEEBBTTSSS-...EEEETTSEEEEEEEEEE CS
    Rrp44_S1    2 eeegyvikvfsNGvvvlvprfGiEglirledlaeeees.................keaefdeeeykleveekkkekk...vtvelFdkvkVkvksek 78  
                   eegy+++vf+NGvvv+vprfGiEg++rled+  + e+                 +e+e+d+eey+l+v +k++ ++   + velF++v+V+v+s+k
  EEA20376.1  909 DEEGYIMRVFENGVVVFVPRFGIEGIVRLEDFMLPGEKvlpnvhdpeqmrevahrRESEYDAEEYTLRVWDKNHPETersLMVELFERVQVNVSSVK 1005
                  79*********************************9999****************9****************9988788899*************** PP

                  -SS...SSSEEEE CS
    Rrp44_S1   79 des...tgkrkvk 88  
                  +e     gkrkv+
  EEA20376.1 1006 EEGgrsAGKRKVR 1018
                  *961114566665 PP

>> OB_Dis3  Dis3-like cold-shock domain 2 (CSD2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0         3   8.9e+03       9      40 ..     189     219 ..     187     226 .. 0.78
   2 !   72.1   0.0   9.6e-24   2.9e-20       2      77 .]     411     478 ..     410     478 .. 0.98

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 3
                 TTS--EEEETTSSTTTHHHHTTTTTT--EEEE CS
     OB_Dis3   9 krlPriliptkelpeeflenpeelegklfvvk 40 
                 k +P i++ t++  e++++ +ee   +l ++ 
  EEA20376.1 189 KTIPEIVVLTDDK-ENLRKAKEEGVTALSLAA 219
                 6899999999997.888888888777766655 PP

  == domain 2  score: 72.1 bits;  conditional E-value: 9.6e-24
                 EEE--SSTTS--EEEETTSSTTTHHHHTTTTTT--EEEEE----TT-SS-EEEEEEE-HHHHHHHHHHHHHHHHTT CS
     OB_Dis3   2 vlfkPldkrlPriliptkelpeeflenpeelegklfvvkidsWsetsryPlGeivksLGeagdieaeteaiLleng 77 
                 v++ P+dkr+P+i+i+t+++        +el g++++v++dsW+ +sryP G++v+sLGe ++  aetea+Lle++
  EEA20376.1 411 VFVLPMDKRIPKIRIRTRQA--------AELLGQRILVTVDSWDRDSRYPTGHFVRSLGELETKGAETEALLLEYD 478
                 8999****************........**********************************************96 PP

>> PIN_4  PIN domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.2   0.1   1.4e-14   4.3e-11       1     129 [.      87     216 ..      87     218 .. 0.83

  Alignments for each domain:
  == domain 1  score: 43.2 bits;  conditional E-value: 1.4e-14
       PIN_4   1 fVlDTnvlLhdpealksfkeehdvviPitVleELdklKkgsserelarlarqanrlldellekesgrlkvqtsaeelpeeeseseknDnrIlavalelk 99 
                 +V DTn lL+ ++++++    +dv+i +tVleEL++l      ++l +l++   + ++  +++   +  v+++++e  +   +  +nD+++  va ++ 
  EEA20376.1  87 IVPDTNALLNGMDVFEHTGAFYDVIILQTVLEELRNLSLPLY-NRLISLIKTDEKRFYLFFNEFRLETYVRRQNDESIN---D--RNDRAVRTVAKWYT 179
                 699************************************999.666666666666666666655555555544433333...4..9************* PP

       PIN_4 100 eekp.......drkvvLvskDinlrikAkalgieaed 129
                 e+ +         ++v +++D+++  kAk +g+ a +
  EEA20376.1 180 EHLRqaakgktIPEIVVLTDDKENLRKAKEEGVTALS 216
                 ***99**99998999******************9976 PP

>> CSD2  Cold shock domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.1   0.00034         1      17      58 ..     298     341 ..     287     352 .. 0.74
   2 !   25.2   0.0   4.5e-09   1.3e-05       1      71 [.     412     481 ..     412     485 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00034
        CSD2  17 keklkgakdGdkVvveiteypdkknpeGevi..evLGkkgdpgv 58 
                 +++ + a++Gd+Vvve++  ++ k+p  ++i  e   k++ p++
  EEA20376.1 298 RDNSNRAVSGDIVVVEVLPKDQWKSPSSKIIdeEAVTKNENPDI 341
                 678899**********9987655889999983345555555555 PP

  == domain 2  score: 25.2 bits;  conditional E-value: 4.5e-09
        CSD2   1 FVvpddkrlkqdifipkeklkgakdGdkVvveiteyp.dkknpeGevievLGkkgdpgveilsilakhglpe 71 
                 FV p dkr+++ i i  +++     G+ ++v + +++ d + p+G+ +++LG+ +++g+e ++ l ++++++
  EEA20376.1 412 FVLPMDKRIPK-IRIRTRQAA-ELLGQRILVTVDSWDrDSRYPTGHFVRSLGELETKGAETEALLLEYDVQY 481
                 9*********5.888866444.335***********845567***************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1025 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       567  (0.0316247); expected 358.6 (0.02)
Passed bias filter:                      457  (0.0254894); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.74u 0.26s 00:00:01.00 Elapsed: 00:00:00.42
# Mc/sec: 7286.90
//
Query:       EEA20377.1  [L=773]
Description: LIM domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      3e-27   94.6  21.2    2.4e-10   40.5   4.8    3.7  3  LIM              LIM domain
  ------ inclusion threshold ------
      0.017   15.7   3.8      0.044   14.4   3.8    1.7  1  Ribosomal_60s    60s Acidic ribosomal protein
        0.2   12.2   0.1        0.2   12.2   0.1    2.7  3  Zn_ribbon_recom  Recombinase zinc beta ribbon domain


Domain annotation for each model (and alignments):
>> LIM  LIM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.1   1.9   6.2e-10   3.7e-06       1      43 [.     559     599 ..     559     634 .. 0.86
   2 !   40.5   4.8     4e-14   2.4e-10       1      57 [.     638     693 ..     638     694 .. 0.95
   3 !   36.8   0.6   5.7e-13   3.4e-09       1      47 [.     698     744 ..     698     769 .. 0.93

  Alignments for each domain:
  == domain 1  score: 27.1 bits;  conditional E-value: 6.2e-10
                 -TTT--BE-TTTEEEEETTEEEETTTSB-TTT-SB-CTT.CEE CS
         LIM   1 CagCnkkiadrelvlkaldkvwHeeCFtCsdCqkeLkegsfye 43 
                 C +C  +i+ r ++  a + ++H+eCF C +C++ L+   fy+
  EEA20377.1 559 CMNCVLPIEGRVVT--AAGSRFHPECFSCYHCGTGLECVAFYQ 599
                 999******99999..******************999877655 PP

  == domain 2  score: 40.5 bits;  conditional E-value: 4e-14
                 -TTT--BE-TTTEEEEETTEEEETTTSB-TTT-SB-CTT..CEEETTEEEEHHHHHHH CS
         LIM   1 CagCnkkiadrelvlkaldkvwHeeCFtCsdCqkeLkegs.fyekdgklyCkkdylkk 57 
                 C++C+ +i+ + +v  a +  wH+ +F C++C++++++++ f+ekdg   C +++ ++
  EEA20377.1 638 CKSCKTPIEGEVVV--ACGAEWHVGHFFCAECGDPFSQETpFVEKDGFAWCLHCHSRR 693
                 *********88888..***************************************886 PP

  == domain 3  score: 36.8 bits;  conditional E-value: 5.7e-13
                 -TTT--BE-TTTEEEEETTEEEETTTSB-TTT-SB-CTT..CEEETTE CS
         LIM   1 CagCnkkiadrelvlkaldkvwHeeCFtCsdCqkeLkegs.fyekdgk 47 
                 C gC++++ ++ +v  al+ +wH +CF+C +C+  + +++ f++k+g+
  EEA20377.1 698 CLGCKQPVLEDVIV-TALGGQWHDKCFVCHTCGGGFGPEGrFFVKEGE 744
                 99*******99999.6************************99999986 PP

>> Ribosomal_60s  60s Acidic ribosomal protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   3.8   7.4e-06     0.044      56      83 ..     393     420 ..     365     424 .. 0.57

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 7.4e-06
                    XXXXXXXXXXXXXXXXXXXX.XX--SS- CS
  Ribosomal_60s  56 aaaaaaaaaaaeekkkeeeeeEeedddm 83 
                    +++  +++++a e+++eeeeeEee+  m
     EEA20377.1 393 SQESRKKEKEAVEEEEEEEEEEEEEVRM 420
                    2333333333444444444435666666 PP

>> Zn_ribbon_recom  Recombinase zinc beta ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   1.5         3   1.8e+04      25      31 ..     584     590 ..     559     594 .. 0.69
   2 ?   12.2   0.1   3.4e-05       0.2       4      53 ..     660     710 ..     659     714 .. 0.67
   3 ?   -1.8   0.5      0.78   4.6e+03       7      16 ..     724     733 ..     722     751 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 3
  Zn_ribbon_recom  25 hyYrCst 31 
                       +Y+C+t
       EEA20377.1 584 SCYHCGT 590
                      4566655 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 3.4e-05
  Zn_ribbon_recom   4 GllrCgeCGspmtrrkrk..gkr...hyYrCstyrrkgkkCsnhsireekleeav 53 
                      G  +C+eCG p+++ +    + +    + +C ++r+   +C +   ++++le+++
       EEA20377.1 660 GHFFCAECGDPFSQETPFveK-DgfaWCLHCHSRRTAS-RCLG--CKQPVLEDVI 710
                      889***********8744322.2344778999998888.5442..4455555555 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 0.78
  Zn_ribbon_recom   7 rCgeCGspmt 16 
                      +C  CG+ + 
       EEA20377.1 724 VCHTCGGGFG 733
                      8*****9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (773 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1695  (0.0945396); expected 358.6 (0.02)
Passed bias filter:                      714  (0.0398237); expected 358.6 (0.02)
Passed Vit filter:                        89  (0.00496402); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.83u 0.30s 00:00:01.12 Elapsed: 00:00:00.44
# Mc/sec: 5336.89
//
Query:       EEA20378.1  [L=364]
Description: methyltransferase-like protein 1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      1e-42  145.5   1.0    6.4e-28   97.4   0.0    3.2  3  Methyltransf_4   Putative methyltransferase
    0.00083   18.4   0.1      0.066   12.2   0.0    2.1  2  DUF913           Domain of Unknown Function (DUF913)
     0.0054   17.4   0.0      0.037   14.7   0.0    2.3  2  Methyltransf_25  Methyltransferase domain
  ------ inclusion threshold ------
       0.01   15.8   0.0      0.029   14.4   0.0    1.7  2  Methyltransf_32  Methyltransferase domain
      0.016   14.8   0.0       0.18   11.3   0.0    2.1  2  MTS              Methyltransferase small domain
      0.026   15.3   0.1       0.17   12.6   0.0    2.4  3  Methyltransf_12  Methyltransferase domain
      0.083   12.7   0.0       0.18   11.6   0.0    1.6  1  Methyltransf_31  Methyltransferase domain
        0.3   11.7  10.9        0.7   10.5   7.2    2.4  2  Ribosomal_60s    60s Acidic ribosomal protein
       0.67   10.5   5.5        6.4    7.3   1.2    2.3  2  DUF3391          Domain of unknown function (DUF3391)
        9.9    4.5   7.8         14    3.9   7.8    1.1  1  Cytomega_UL84    Cytomegalovirus UL84 protein


Domain annotation for each model (and alignments):
>> Methyltransf_4  Putative methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.8   0.0   4.9e-11   8.7e-08       3      49 ..      85     131 ..      83     141 .. 0.90
   2 !   97.4   0.0   3.6e-31   6.4e-28      49     133 ..     186     270 ..     171     304 .. 0.82
   3 !   13.6   0.1   1.9e-05     0.033     131     171 ..     309     349 ..     293     351 .. 0.86

  Alignments for each domain:
  == domain 1  score: 31.8 bits;  conditional E-value: 4.9e-11
                     EEEEEET-TTSHHHHHHHHHSTTSEEEEEES-HHHHHHHHHHHHHCT CS
  Methyltransf_4   3 pvvleiGcGkGeflvalAkknPdknflGiEirvkvvakvlkkieale 49 
                     + v++iGcG G++l+ lA+  P+++++G+Eir++v+++v  +++al+
      EEA20378.1  85 VEVADIGCGFGGLLIGLAPVLPETLMVGLEIRSQVTEYVKVRVAALR 131
                     6799***********************************99998875 PP

  == domain 2  score: 97.4 bits;  conditional E-value: 3.6e-31
                     TTSSEEEEES-CCCHHHHCS-TTSEEEEEEES-----SGGGGGGSTTSHHHHHHHHHHEEEEEEEEEEESHHHHHHHHHHHHHCS CS
  Methyltransf_4  49 elkNlrilrgdalkvllelledgslekifilFPDPwfKkrhhKrRllqpellkelarvLkkgGvlelaTDveeyaeemlkvleee 133
                     +++N+  +r + +k+l++++  ++l+kifi+FPDP+fK+r+h++R++++ l +e+a vLk+gG+l+++TDveey++++l ++   
      EEA20378.1 186 GYQNISAIRANTMKFLPRFFGHHQLSKIFICFPDPHFKARKHRQRIISSSLNAEYAFVLKPGGLLYTITDVEEYHYWVLRHFGVL 270
                     89******************************************************************************99765 PP

  == domain 3  score: 13.6 bits;  conditional E-value: 1.9e-05
                     HCSTTEEESSCCCSCCTCHCHHCCCSSTTCCCCCCTTSS-E CS
  Methyltransf_4 131 eeeplferlskeeeleeeplsvlriatkyeqkvqskgkeiy 171
                     +  +lfer+s+ee  ++e+++v+r+ t++++kv +++++++
      EEA20378.1 309 RVRELFERVSDEELAADECVKVMREETEEGKKVARNKGPKF 349
                     44567********************************9987 PP

>> DUF913  Domain of Unknown Function (DUF913)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.2   0.0   3.7e-05     0.066     270     348 ..     139     215 ..     101     220 .. 0.57
   2 !    4.3   0.1    0.0093        17     275     301 ..     277     320 ..     237     353 .. 0.55

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 3.7e-05
      DUF913 270 skseasssssssetkeeekssededvemedaeeetesesdeseeseeekeknslldyilnvakFLeallsnnslcreFv 348
                 ++s+++s++++++++ e ++++ +++  ed  +++  +s+++++s  +  +++++    n++kFL +++ +++l + F+
  EEA20378.1 139 AASSSTSTPAPTTEEPEPTNNQTQEDLPED--APALPDSTQEAQSLIPGGYQNISAIRANTMKFLPRFFGHHQLSKIFI 215
                 111111111111111111111222212222..355566666677777788888********************999997 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.0093
      DUF913 275 sssssssetkeeek...ssededvemeda..............e 301
                 ++++++++++ee+k   +++ded+++e++              e
  EEA20378.1 277 AAENTATTAQEEKKaeaEEDDEDEDDENSgvarvrelfervsdE 320
                 22222222222333122333333233322445555555544440 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   2.1e-05     0.037       1      50 [.      87     137 ..      87     152 .. 0.81
   2 ?   -0.9   0.0       1.5   2.8e+03      85      97 .]     236     248 ..     173     248 .. 0.60

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 2.1e-05
                      EEEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHH.TTTTEEE CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlgkakvtgvDiseemleaareraee.eglnvef 50 
                      v d+GcG G l++ la  l++  ++g++i ++  e+++ r+++ ++ ++++
       EEA20378.1  87 VADIGCGFGGLLIGLAPVLPETLMVGLEIRSQVTEYVKVRVAAlRNQQARL 137
                      78****************999***************999887632224444 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 1.5
                      HHHHHHHHEEEEE CS
  Methyltransf_25  85 alkeiarvLkpgG 97 
                      + +e a vLkpgG
       EEA20378.1 236 LNAEYAFVLKPGG 248
                      4467777899988 PP

>> Methyltransf_32  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   1.6e-05     0.029      25     101 ..      83     155 ..      64     182 .. 0.74
   2 ?   -2.2   0.2       2.1   3.7e+03     108     108 ..     295     295 ..     269     339 .. 0.54

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.6e-05
  Methyltransf_32  25 galtvvDvGaGkgYLsfvlalkekeyklkvvgidakeelvekaekraeklgkkfnkrlsfaelsieeatssktltkk 101
                      ++++v+D+G+G g L   la   +  ++ +vg++++++++e  + r ++l+++  +rl+ a  s+++    +t++ +
       EEA20378.1  83 KDVEVADIGCGFGGLLIGLAP--VLPETLMVGLEIRSQVTEYVKVRVAALRNQQ-ARLRAASSSTSTPAP-TTEEPE 155
                      5689*************9999..658999*********************9544.777776666554443.322222 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 2.1
  Methyltransf_32 108 k 108
                      +
       EEA20378.1 295 E 295
                      1 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0    0.0001      0.18      31      77 ..      83     129 ..      69     149 .. 0.76
   2 ?    1.0   0.0      0.16   2.8e+02     105     141 ..     220     256 ..     208     277 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.0001
                 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHH CS
         MTS  31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenlea 77 
                 ++ +v+D+GcG+G l + la   pe+ ++ +++  +  e  k  ++a
  EEA20378.1  83 KDVEVADIGCGFGGLLIGLAPVLPETLMVGLEIRSQVTEYVKVRVAA 129
                 45579********************9899898888877777766555 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.16
                 --STTTCHCHHHHHHHHHHHHHHHEEEEEEEEEEEET CS
         MTS 105 PPfhagkatelavaeeliaeAkeaLkegGeLliVanr 141
                 P f+a k+ +  +   l ae + +Lk+gG L+ ++  
  EEA20378.1 220 PHFKARKHRQRIISSSLNAEYAFVLKPGGLLYTITDV 256
                 77999999999999999999999******99998754 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   9.4e-05      0.17       2      48 ..      89     135 ..      88     150 .. 0.87
   2 ?   -2.4   0.0       4.5   8.1e+03      91      99 .]     242     250 ..     230     250 .. 0.77
   3 ?   -1.9   0.1       3.3   5.9e+03      49      56 ..     293     300 ..     266     334 .. 0.47

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 9.4e-05
  Methyltransf_12   2 eiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnn 48 
                      +iGcG G ll  l++ lp++  +g++i +++ e  k + a+ +n+++
       EEA20378.1  89 DIGCGFGGLLIGLAPVLPETLMVGLEIRSQVTEYVKVRVAALRNQQA 135
                      8******************************9999999988887553 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 4.5
  Methyltransf_12  91 klLkpgGrl 99 
                       +LkpgG l
       EEA20378.1 242 FVLKPGGLL 250
                      69*****86 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 3.3
  Methyltransf_12  49 nnveleal 56 
                      ++ + e++
       EEA20378.1 293 AEEDDEDE 300
                      22222222 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0    0.0001      0.18       3      52 ..      83     131 ..      81     156 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.0001
  Methyltransf_31   3 kglrvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielArenaqklg 52 
                      k+++v D+GCG G l++ la  + p+  +vG++i  ++ e+ + + + l 
       EEA20378.1  83 KDVEVADIGCGFGGLLIGLA-PVLPETLMVGLEIRSQVTEYVKVRVAALR 131
                      7899****************.8889999****999888777776666555 PP

>> Ribosomal_60s  60s Acidic ribosomal protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.1      0.18   3.2e+02      39      69 ..     127     159 ..     102     170 .. 0.48
   2 ?   10.5   7.2   0.00039       0.7      53      83 ..     276     303 ..     264     308 .. 0.55

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.18
                    XXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXX CS
  Ribosomal_60s  39 langaakla..aaaaaaaaaaaaaaaaaaaeek 69 
                    +a+ +++ a   aa++++++ a+  ++++    
     EEA20378.1 127 VAALRNQQArlRAASSSTSTPAPTTEEPEPTNN 159
                    334443433553334444444444444443333 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00039
                    XXXXXXXXXXXXXXXXXXXXXXX.XX--SS- CS
  Ribosomal_60s  53 aaaaaaaaaaaaaaeekkkeeeeeEeedddm 83 
                    +   aa+  a  a+eekk+e+ee++e++dd+
     EEA20378.1 276 P---AAENTATTAQEEKKAEAEEDDEDEDDE 303
                    3...344445555555555555543444443 PP

>> DUF3391  Domain of unknown function (DUF3391)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.2     0.018        32      45     107 ..     117     179 ..     113     213 .. 0.50
   2 ?    7.3   1.2    0.0036       6.4      70     114 ..     273     317 ..     250     344 .. 0.71

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.018
     DUF3391  45 asgiqeVwidtdksdeeelagldvpaaeaaeeakaaeesaeleeekqerperleaere....elera 107
                 ++  ++V + ++  ++++   + ++++    ++++a++++e+e ++++++e+l ++++    + ++a
  EEA20378.1 117 SQVTEYVKVRVAALRNQQARLRAASSS----TSTPAPTTEEPEPTNNQTQEDLPEDAPalpdSTQEA 179
                 555555655555544444444433333....333333333333334444444444444222233333 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0036
     DUF3391  70 aaeaaeeakaaeesaeleeekqerperleaereeleraeklyeea 114
                 +a++a+e++a+++++e+++e++e+ e+++ e++ ++r+++l+e+ 
  EEA20378.1 273 DAKPAAENTATTAQEEKKAEAEEDDEDEDDENSGVARVRELFERV 317
                 344455666667777777777777777777778888888877764 PP

>> Cytomega_UL84  Cytomegalovirus UL84 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   7.8    0.0081        14     150     194 ..     277     321 ..     271     332 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.0081
  Cytomega_UL84 150 qeeetaashepekkkekeekkeeededdrnddrergilcvvsned 194
                      e+ta++ + ekk e ee  e+ed+++    r r ++  vs+e+
     EEA20378.1 277 AAENTATTAQEEKKAEAEEDDEDEDDENSGVARVRELFERVSDEE 321
                    568999999**********99999999999999999999999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (364 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1120  (0.0624686); expected 358.6 (0.02)
Passed bias filter:                      677  (0.0377601); expected 358.6 (0.02)
Passed Vit filter:                        77  (0.00429472); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.42
# Mc/sec: 2618.45
//
Query:       EEA20379.1  [L=237]
Description: ESCRT-II complex component (Vps25), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.2e-49  165.9   0.6    8.3e-49  165.4   0.6    1.2  1  ESCRT-II  ESCRT-II complex subunit


Domain annotation for each model (and alignments):
>> ESCRT-II  ESCRT-II complex subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  165.4   0.6   4.6e-53   8.3e-49       1     140 []      57     206 ..      57     206 .. 0.96

  Alignments for each domain:
  == domain 1  score: 165.4 bits;  conditional E-value: 4.6e-53
    ESCRT-II   1 eysFpPfFTlqpnlttrkkqlekWsslilaycrhhrifklslseaeeeeeeselFknkkinRrlsledirevleelvkkg.......raewv....... 85 
                 +y++p+fFTlqpn++tr++q++ W++l+ ++cr hr+f+lsl+    e+ es+lF+n k+++r++l+++re+++++v  +       raewv       
  EEA20379.1  57 VYDWPAFFTLQPNAQTRQAQMRRWANLVSDWCRYHRTFRLSLT----EAVESPLFCNAKMRKRVALQEAREIVDWMVMPQedggggrRAEWVpaatagg 151
                 59*****************************************....34567************************988778899*9**********99 PP

    ESCRT-II  86 dkekskalvywrtpeewasliyewveetgqkgsvlTlyeLtegdetrgeefhgld 140
                 ++ek+ a+++wr+peewa+li +wveet+qk++vlT+yeL +g++t+++efhg+d
  EEA20379.1 152 GSEKTIAWIWWRRPEEWAKLIADWVEETAQKNTVLTVYELIHGEATTSQEFHGMD 206
                 88899*************************************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (237 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       537  (0.0299515); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1723.55
//
Query:       EEA20380.1  [L=855]
Description: DNA repair protein Rtt107, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.4e-37  126.2   0.6    1.1e-20   73.4   0.2    6.4  6  PTCB-BRCT      twin BRCT domain
    1.5e-35  121.0   0.0    1.3e-31  108.4   0.0    3.9  4  RTT107_BRCT_5  Regulator of Ty1 transposition protein 107 BRC
    4.1e-32  110.4   0.0    2.4e-09   37.4   0.0    6.9  6  BRCT           BRCA1 C Terminus (BRCT) domain
    3.6e-25   88.2   0.0      4e-06   27.1   0.0    6.5  6  BRCT_2         BRCT domain, a BRCA1 C-terminus domain
    8.2e-12   45.2   0.0    0.00033   20.9   0.0    4.5  4  LIG3_BRCT      DNA ligase 3 BRCT domain
  ------ inclusion threshold ------
       0.01   15.9   0.0        4.4    7.4   0.0    3.2  3  BRCT_3         BRCA1 C Terminus (BRCT) domain
        8.5    5.7  10.9         13    5.1  10.9    1.2  1  Mcm10          Mcm10 replication factor


Domain annotation for each model (and alignments):
>> PTCB-BRCT  twin BRCT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.0   5.8e-05      0.15       1      63 []      15      84 ..      15      84 .. 0.85
   2 !   22.1   0.0   4.2e-08   0.00011       5      63 .]     115     175 ..     111     175 .. 0.83
   3 !    8.7   0.0   0.00063       1.6      13      63 .]     260     309 ..     252     309 .. 0.84
   4 !   73.4   0.2   4.1e-24   1.1e-20       1      63 []     342     404 ..     342     404 .. 0.99
   5 ?    0.4   0.0      0.25   6.3e+02      27      42 ..     654     668 ..     635     684 .. 0.77
   6 ?   -1.3   0.0      0.87   2.2e+03      15      28 ..     753     766 ..     742     767 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 5.8e-05
                -EEEEECB-TTCHHHHHHHHHHTT-EEESS.....E..ETT-SEEEECSS-CHHHHHHHHCT-EEE-CHH CS
   PTCB-BRCT  1 lvicvtgysgddrkslqklieamGaeyskd.....l..tksvTHLicksgeGekyekAkkwgipvVsveW 63
                +v+c  g++gd+  +l  li+++G+e + +     +   ++ TH i+ ++    y+ A    ipvV+++W
  EEA20380.1 15 CVACCNGIEGDAVMQLDILITEHGGEAVIHeepapFppVEQFTHIISLTADFPAYQSACDALIPVVKPQW 84
                579999******************9987552233333359****************************** PP

  == domain 2  score: 22.1 bits;  conditional E-value: 4.2e-08
                 EECB-TTCHHHHHHHHHHTT-EEESSEETT-SEEEECSS-CHHHHH..HHHCT-EEE-CHH CS
   PTCB-BRCT   5 vtgysgddrkslqklieamGaeyskdltksvTHLicksgeGekyek..AkkwgipvVsveW 63 
                    + + d++ +   + amG+ ys ++t +vTHL+  s+e++k++    k+ g ++V + W
  EEA20380.1 115 CGDIPDGDKDAIIGGVMAMGGLYSPRVTSQVTHLVDLSMESDKAKLiiSKSLGAKIVLPHW 175
                 5556667788899999***************************996336788888888887 PP

  == domain 3  score: 8.7 bits;  conditional E-value: 0.00063
                 HHHHHHHHHHTT-EEESSEETT-SEEEECSS-CHHHHHHHHCT-EEE-CHH CS
   PTCB-BRCT  13 rkslqklieamGaeyskdltksvTHLicksgeGekyekAkkwgipvVsveW 63 
                 ++s+++l+++  ++++kdl+ +   +ic+  eG  y+ A +w+  v ++ W
  EEA20380.1 260 LESIEDLVKQGNGTITKDLR-KADMFICRYREGFEYRTASRWNKDVGNLSW 309
                 789999999999******95.46789****************977766666 PP

  == domain 4  score: 73.4 bits;  conditional E-value: 4.1e-24
                 -EEEEECB-TTCHHHHHHHHHHTT-EEESSEETT-SEEEECSS-CHHHHHHHHCT-EEE-CHH CS
   PTCB-BRCT   1 lvicvtgysgddrkslqklieamGaeyskdltksvTHLicksgeGekyekAkkwgipvVsveW 63 
                 l+i++++y g++r +l++li+a Gae++k+l++++THLi ++g++ek+ +Ak+wg++vV+++W
  EEA20380.1 342 LRISLSNYAGEARAYLENLIQAAGAECTKTLKTNNTHLITAHGNSEKCAAAKEWGLQVVNHLW 404
                 79************************************************************* PP

  == domain 5  score: 0.4 bits;  conditional E-value: 0.25
                 EESSEETT-SEEEECS CS
   PTCB-BRCT  27 yskdltksvTHLicks 42 
                 +++d +k++THL ++s
  EEA20380.1 654 ITQD-AKKCTHLAAPS 668
                 4444.699****8765 PP

  == domain 6  score: -1.3 bits;  conditional E-value: 0.87
                 HHHHHHHHTT-EEE CS
   PTCB-BRCT  15 slqklieamGaeys 28 
                  ++ ++ea+G+e++
  EEA20380.1 753 AFRSIVEANGGECT 766
                 57889*******97 PP

>> RTT107_BRCT_5  Regulator of Ty1 transposition protein 107 BRCT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.0      0.14   3.6e+02      77      98 ..      79     100 ..      71     101 .. 0.89
   2 !    6.2   0.0    0.0038       9.6      66     100 .]     159     193 ..     142     193 .. 0.88
   3 !  108.4   0.0     5e-35   1.3e-31       2     100 .]     607     708 ..     606     708 .. 0.97
   4 ?   -2.8   0.0       2.3   5.8e+03      73      92 ..     823     842 ..     822     849 .. 0.75

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.14
                    EE-CHHHHHHHHHTS---SGGG CS
  RTT107_BRCT_5  77 ilspdfiedvLkkkklldleey 98 
                    +++p+++++ + k+kl ++ ++
     EEA20380.1  79 VVKPQWLQTSIAKGKLANPRQF 100
                    89**************999887 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.0038
                    HHHHHCCCTTEEE-CHHHHHHHHHTS---SGGGB- CS
  RTT107_BRCT_5  66 KFLksLskapkilspdfiedvLkkkklldleeyll 100
                    K + s s + ki+ p++ +d+Lk ++ +d+ +y l
     EEA20380.1 159 KLIISKSLGAKIVLPHWFDDCLKLGRRIDERPYTL 193
                    6777889999*************988899999975 PP

  == domain 3  score: 108.4 bits;  conditional E-value: 5e-35
                    HHHHHHHTSSSXXX--EEEEESSS.TT.....SSHHHHHHHHHTTEEE-SGCCT-SEEE-SS---SHHHHHHCCCTTEEE-CHHHHHHHHHTS--- CS
  RTT107_BRCT_5   2 kkekkkkkkkskpevkiravlTgceeevn...kedsdkkkLrklGikivqeakkcntliApkilRTeKFLksLskapkilspdfiedvLkkkklld 94 
                    +++++k++k+ k++v++++++Tg++++v+   ked+dk++Lr+lGi i+q+akkc++l+Ap+ilRT KF+++L++ap +++ d+++++L k++lld
     EEA20380.1 607 EEKETKRQKNGKTPVTMHLMITGFQRWVGnmkKEDADKRQLRNLGIAITQDAKKCTHLAAPSILRTPKFVNALAYAPVVVHIDYVTECLAKDELLD 702
                    678999**********************99****************************************************************** PP

                    SGGGB- CS
  RTT107_BRCT_5  95 leeyll 100
                    ++++ l
     EEA20380.1 703 PDDFAL 708
                    **9975 PP

  == domain 4  score: -2.8 bits;  conditional E-value: 2.3
                    CTTEEE-CHHHHHHHHHTS- CS
  RTT107_BRCT_5  73 kapkilspdfiedvLkkkkl 92 
                    k p i++++++ d+  ++++
     EEA20380.1 823 KTPRIVNVNWLLDIAMSQEI 842
                    5789*******998666555 PP

>> BRCT  BRCA1 C Terminus (BRCT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.0   1.3e-05     0.034       3      79 .]       6      89 ..       4      89 .. 0.83
   2 !   30.7   0.0   1.2e-10     3e-07       5      79 .]     107     180 ..     104     180 .. 0.93
   3 !    7.3   0.0    0.0024       6.1      24      79 .]     262     314 ..     256     314 .. 0.80
   4 !   37.4   0.0   9.4e-13   2.4e-09       6      78 ..     339     408 ..     337     409 .. 0.97
   5 !    9.2   0.0   0.00061       1.6      20      79 .]     637     695 ..     634     695 .. 0.86
   6 ?    1.7   0.0      0.14   3.5e+02       4      77 ..     734     835 ..     731     837 .. 0.62

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 1.3e-05
                TTTTTTEEEEEEESTSSHHHHHH...HHHHHHTTCEE.......ESSCSTTSSEEEESSSHSHHHHHHHHHHTTSEEEETHHHHHHH CS
        BRCT  3 ellfhgckfvitgvldnftrdel...eelikehGGkv.......ttevskktthlvvgepesrslkylealklnipivheewlldci 79
                ++l+++ck+++   +++++ d       li ehGG              ++ th++  +   +   y+ a +  ip+v+++wl  +i
  EEA20380.1  6 PPLLSDCKICV-ACCNGIEGDAVmqlDILITEHGGEAviheepaPFPPVEQFTHIISLTA--DFPAYQSACDALIPVVKPQWLQTSI 89
                789********.8888888888877799********988888875555666777775555..889******************9876 PP

  == domain 2  score: 30.7 bits;  conditional E-value: 1.2e-10
                 TTTTEEEEEEESTSSHHHHHHHHHHHHTTCEEESSCSTTSSEEEESSS..HSHHHHHHHHHHTTSEEEETHHHHHHH CS
        BRCT   5 lfhgckfvitgvldnftrdeleelikehGGkvttevskktthlvvgep..esrslkylealklnipivheewlldci 79 
                 +f+++++ + g   + ++d +   +  +GG ++++v++++thlv      es++ k+  +++l+ +iv + w+ dc+
  EEA20380.1 107 FFSDVVVTC-GDIPDGDKDAIIGGVMAMGGLYSPRVTSQVTHLVD--LsmESDKAKLIISKSLGAKIVLPHWFDDCL 180
                 7999*****.**********************************3..244799***********************7 PP

  == domain 3  score: 7.3 bits;  conditional E-value: 0.0024
                 HHHHHHHHTTCEEESSCSTTSSEEEESSSHSHHHHHHHHHHTTSEEEETHHHHHHH CS
        BRCT  24 eleelikehGGkvttevskktthlvvgepesrslkylealklnipivheewlldci 79 
                 ++e+l+k   G++t+++ k + ++    + +++ +y +a ++n+ + + +wl+++i
  EEA20380.1 262 SIEDLVKQGNGTITKDLRKADMFIC--RY-REGFEYRTASRWNKDVGNLSWLFYLI 314
                 6778888888888777765555444..66.799*******************9987 PP

  == domain 4  score: 37.4 bits;  conditional E-value: 9.4e-13
                 TTTEEEEEEESTSSHHHHHHHHHHHHTTCEEESSCSTTSSEEEESSSHSHHHHHHHHHHTTSEEEETHHHHHH CS
        BRCT   6 fhgckfvitgvldnftrdeleelikehGGkvttevskktthlvvgepesrslkylealklnipivheewlldc 78 
                 f+g+ + + +++ ++ r +le+li+  G+ +t+ +++++thl++ +    s+k+ +a++++  +v++ wl ++
  EEA20380.1 339 FKGLRISL-SNYAGEARAYLENLIQAAGAECTKTLKTNNTHLITAHG--NSEKCAAAKEWGLQVVNHLWLEES 408
                 899*****.***********************************999..999******************886 PP

  == domain 5  score: 9.2 bits;  conditional E-value: 0.00061
                 HHHHHH.HHHHHHTTCEEESSCSTTSSEEEESSSHSHHHHHHHHHHTTSEEEETHHHHHHH CS
        BRCT  20 ftrdel.eelikehGGkvttevskktthlvvgepesrslkylealklnipivheewlldci 79 
                 ++++++ ++ ++++G  + t+  kk+thl + +  +r+ k+  al+    +vh++++ +c+
  EEA20380.1 637 MKKEDAdKRQLRNLGIAI-TQDAKKCTHLAAPSI-LRTPKFVNALAYAPVVVHIDYVTECL 695
                 555555677788888888.666789******999.*************************7 PP

  == domain 6  score: 1.7 bits;  conditional E-value: 0.14
                 TTTTTEEEEEEESTSSHHHHHHHHHHHHTTCEE.......................ESSCSTTSSEEEESSS......HSHHHHHHHHHHTTSEEEETH CS
        BRCT   4 llfhgckfvitgvldnftrdeleelikehGGkv.......................ttevskktthlvvgep......esrslkylealklnipivhee 73 
                 +l+++  +++ +       d  +++++ +GG +                        ++ ++++ +l+ g+       + r   +     +  +iv+ +
  EEA20380.1 734 KLLRDYRICC-VETIRGGFDAFRSIVEANGGECtlfrgrvsmnehrrregsessgeADQPMRDDIFLISGDEpehvkvWPRFRQMVLEAGKTPRIVNVN 831
                 5666666666.4444444455577888888888777777777777777777777777777777777777777444444333333555555556788888 PP

                 HHHH CS
        BRCT  74 wlld 77 
                 wlld
  EEA20380.1 832 WLLD 835
                 8887 PP

>> BRCT_2  BRCT domain, a BRCA1 C-terminus domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0   7.1e-07    0.0018      20      84 ..      26     100 ..      10     101 .. 0.80
   2 !   14.3   0.0   1.6e-05      0.04      16      84 ..     118     191 ..     103     192 .. 0.87
   3 ?    4.6   0.0     0.017        43      22      51 ..     261     290 ..     254     318 .. 0.72
   4 !   27.1   0.0   1.6e-09     4e-06       5      83 ..     339     419 ..     337     421 .. 0.92
   5 !   11.4   0.0   0.00013      0.32      54      84 ..     672     706 ..     638     707 .. 0.75
   6 ?    2.8   0.0     0.063   1.6e+02      24      71 ..     754     835 ..     748     842 .. 0.67

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 7.1e-07
      BRCT_2  20 sreklkklIeknGGevveti.......tsavyiviaesneee...laekrkrrvvspkyIkdCikkgkllpleny 84 
                    +l  lI+++GGe v ++        ++ +++i+ + +     +a ++  +vv+p++++ +i+kgkl +++++
  EEA20380.1  26 AVMQLDILITEHGGEAVIHEepapfppVEQFTHIISLTADFPayqSACDALIPVVKPQWLQTSIAKGKLANPRQF 100
                 5678999*******998888566666543455666666554499999999*******************998765 PP

  == domain 2  score: 14.3 bits;  conditional E-value: 1.6e-05
      BRCT_2  16 epspsreklkklIeknGGevvetitsavyiviaesneee.....laekrkrrvvspkyIkdCikkgkllpleny 84 
                 +p+ +++ +   + + GG  +   ts+v++++  s e++      +++ ++++v p++ +dC+k g+ ++ ++y
  EEA20380.1 118 IPDGDKDAIIGGVMAMGGLYSPRVTSQVTHLVDLSMESDkakliISKSLGAKIVLPHWFDDCLKLGRRIDERPY 191
                 5667788888889999999999999999**9999998889999999999*********************9999 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.017
      BRCT_2  22 eklkklIeknGGevvetitsavyiviaesn 51 
                 e +++l+++ +G+++++ ++a+++++  ++
  EEA20380.1 261 ESIEDLVKQGNGTITKDLRKADMFICRYRE 290
                 6799**************999887665444 PP

  == domain 4  score: 27.1 bits;  conditional E-value: 1.6e-09
      BRCT_2   5 FeglrFYindaepspsreklkklIeknGGevvetitsavyiviaesneee...laekrkrrvvspkyIkdCikkgkllplen 83 
                 F+glr  + +++ ++ r+ l+ lI++ G e+++t + +++++i+++ ++e   +a++ +++vv++ +++++ +k k+lp+++
  EEA20380.1 339 FKGLRISL-SNYAGEARAYLENLIQAAGAECTKTLKTNNTHLITAHGNSEkcaAAKEWGLQVVNHLWLEESYAKWKMLPVSD 419
                 78888888.567889****************************99999999*99*************************986 PP

  == domain 5  score: 11.4 bits;  conditional E-value: 0.00013
      BRCT_2  54 e....laekrkrrvvspkyIkdCikkgkllpleny 84 
                 +     a    + vv+ +y+++C++k +ll+++++
  EEA20380.1 672 TpkfvNALAYAPVVVHIDYVTECLAKDELLDPDDF 706
                 45555556667899*****************9986 PP

  == domain 6  score: 2.8 bits;  conditional E-value: 0.063
      BRCT_2  24 lkklIeknGGev.......veti..................tsavyiviaesneee...........laekrkrrvvspkyIkd 71 
                 +++++e+nGGe+       +  +                   ++++++i+  + e            l+  +++r+v+++++ d
  EEA20380.1 754 FRSIVEANGGECtlfrgrvS--MnehrrregsessgeadqpMRDDIFLISGDEPEHvkvwprfrqmvLEAGKTPRIVNVNWLLD 835
                 67899999999955555542..03455666666666666553334555555554447777778888889999999999999877 PP

>> LIG3_BRCT  DNA ligase 3 BRCT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.0   0.00014      0.35      41      80 ..      54      93 ..      37      94 .. 0.91
   2 !   20.9   0.0   1.3e-07   0.00033      28      79 ..     131     183 ..     123     185 .. 0.87
   3 !    6.4   0.0    0.0041        11       6      76 ..     339     409 ..     338     413 .. 0.86
   4 ?   -0.1   0.0      0.47   1.2e+03      38      79 ..     656     698 ..     651     700 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00014
   LIG3_BRCT 41 keaTHvvvskkeeskkekeksknakaVtaewiwesIkkrt 80
                ++ TH+++   +  + + +++    +V ++w+  sI+k++
  EEA20380.1 54 EQFTHIISLTADFPAYQSACDALIPVVKPQWLQTSIAKGK 93
                679******99999**********************9975 PP

  == domain 2  score: 20.9 bits;  conditional E-value: 1.3e-07
   LIG3_BRCT  28 iAydGdlvkeekekeaTHvvvskke..eskkekeksknakaVtaewiwesIkkr 79 
                 +A +G l+++  ++++TH v  + e  + k  ++ks +ak V ++w++++ k +
  EEA20380.1 131 MAMGG-LYSPRVTSQVTHLVDLSMEsdKAKLIISKSLGAKIVLPHWFDDCLKLG 183
                 56777.99*************98766566777899***************9976 PP

  == domain 3  score: 6.4 bits;  conditional E-value: 0.0041
   LIG3_BRCT   6 Ftgvklfipksv.edykklrRYfiAydGdlvkeekekeaTHvvvskkeeskkekeksknakaVtaewiwesI 76 
                 F+g ++ +++   e+++ l+  + A +++  k   +++ TH ++ + + +k  ++k+ + ++V   w+ es 
  EEA20380.1 339 FKGLRISLSNYAgEARAYLENLIQAAGAECTK-TLKTNNTHLITAHGNSEKCAAAKEWGLQVVNHLWLEESY 409
                 89999999998878888999999999998887.667789******8888999999999**********9986 PP

  == domain 4  score: -0.1 bits;  conditional E-value: 0.47
   LIG3_BRCT  38 ekekeaTHvvvskkeeskkekeksknak.aVtaewiwesIkkr 79 
                 +++k++TH  +++  +  k ++    a  +V+ +++ e+ +k 
  EEA20380.1 656 QDAKKCTHLAAPSILRTPKFVNALAYAPvVVHIDYVTECLAKD 698
                 5678899998886655555555555555157889999999886 PP

>> BRCT_3  BRCA1 C Terminus (BRCT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0     0.015        38      61      91 ..      68      98 ..      25     102 .. 0.75
   2 ?   -4.0   0.0       6.2   1.6e+04      65      86 ..     163     184 ..     155     187 .. 0.77
   3 ?    7.4   0.0    0.0017       4.4       3      98 ..     339     424 ..     338     426 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.015
      BRCT_3 61 vlkkaeqlkipvvSteWviQsLIegevlkyd 91
                + + a    ipvv  +W+  s+ +g++ +++
  EEA20380.1 68 AYQSACDALIPVVKPQWLQTSIAKGKLANPR 98
                457788889****************998876 PP

  == domain 2  score: -4.0 bits;  conditional E-value: 6.2
      BRCT_3  65 aeqlkipvvSteWviQsLIege 86 
                 +++l++++v  +W   +L  g+
  EEA20380.1 163 SKSLGAKIVLPHWFDDCLKLGR 184
                 5678899999999988886666 PP

  == domain 3  score: 7.4 bits;  conditional E-value: 0.0017
      BRCT_3   3 lkdlkillvseqkefeelWseilklaGaavvkkekseaeeislgkldvvvtdsscpeevlkkaeqlkipvvSteWviQsLIegevlkydshekyky 98 
                 +k+l+i l +   e +   ++++++aGa+  k+ k+++ +        ++t +  +e+    a++ +++vv   W+ +s  + ++l+++  ++y++
  EEA20380.1 339 FKGLRISLSNYAGEARAYLENLIQAAGAECTKTLKTNNTH--------LITAHGNSEK-CAAAKEWGLQVVNHLWLEESYAKWKMLPVS-DPRYTH 424
                 8999999999999999****************99998865........4566655555.567999999999999999998766666655.788876 PP

>> Mcm10  Mcm10 replication factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1  10.9    0.0051        13      43     206 ..     465     622 ..     436     645 .. 0.62

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0051
       Mcm10  43 kqkderlekrkkkseeiqkrvlseskkpvkss.stskekksalkskksasevpkassslaasklPkLgr.gfsegedvlfldtspptaskssasaeaak 139
                 k   ++       + e+ k+v+++ + ++ ++ s++ +k +a+ ++++ ++ ++++s+la  k+P ++r  ++e+e+v + +ts    s +s+ a aa+
  EEA20380.1 465 KD--QN----IAANTEVTKTVSPQGRAKSVAKsSPAPSKTTAAITPHTNKS-SRKTSNLADAKTPVISRfRADEKENVTPSTTS----SRKSKEAAAAR 552
                 11..22....23334455555544444443331444455555555555555.5555999*********9334566666333333....56788888999 PP

       Mcm10 140 laAiaklkakgkvikkedpna.......vkrKrsdss.kvserveknlksseetkaeseeepaakkkreqlaylk 206
                 l+ ia   a      ++++++        +rK  d +  v ++ +k ++ + +++++ eee + k++++ +  ++
  EEA20380.1 553 LHDIAPDIALY----EKEKKRvggvvygGRRKT-DPDlVVPAKNKKRRSVEPDEEDDIEEEKETKRQKNGKTPVT 622
                 99887544433....333333344433235555.66657777877777777778888888888899888776555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (855 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1008  (0.0562218); expected 358.6 (0.02)
Passed bias filter:                      606  (0.0338); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.78u 0.33s 00:00:01.11 Elapsed: 00:00:00.50
# Mc/sec: 5132.32
//
Query:       EEA20381.1  [L=387]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (387 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       579  (0.032294); expected 358.6 (0.02)
Passed bias filter:                      250  (0.0139439); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.24s 00:00:00.73 Elapsed: 00:00:00.41
# Mc/sec: 2822.32
//
Query:       EEA20382.1  [L=612]
Description: aryl-alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-64  218.5   0.0    1.6e-64  218.2   0.0    1.1  1  GMC_oxred_N    GMC oxidoreductase
    8.9e-31  107.3   0.0    1.7e-30  106.4   0.0    1.5  1  GMC_oxred_C    GMC oxidoreductase
    1.5e-06   27.6   0.3     0.0085   15.2   0.2    2.2  2  FAD_binding_2  FAD binding domain
    0.00014   22.0   0.2    0.00037   20.6   0.2    1.7  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
    0.00031   20.1   0.0       0.56    9.4   0.0    2.4  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
     0.0017   17.6   0.3     0.0069   15.7   0.0    1.8  2  Thi4           Thi4 family
     0.0023   17.6   0.2       0.01   15.4   0.0    2.0  2  DAO            FAD dependent oxidoreductase
     0.0058   15.7   0.1     0.0092   15.1   0.1    1.3  1  Lycopene_cycl  Lycopene cyclase protein
  ------ inclusion threshold ------
       0.06   12.6   0.1          1    8.5   0.0    2.1  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
      0.073   11.8   0.0       0.13   11.0   0.0    1.3  1  HI0933_like    HI0933-like protein


Domain annotation for each model (and alignments):
>> GMC_oxred_N  GMC oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  218.2   0.0   8.8e-68   1.6e-64       1     294 [.      16     329 ..      16     331 .. 0.93

  Alignments for each domain:
  == domain 1  score: 218.2 bits;  conditional E-value: 8.8e-68
  GMC_oxred_N   1 vdelveggGsagsvvAaRLsedpstsvlvleaggreknrl..imvlalalklidkklntayetepekalngrrlilpaGktlGGgsvvNwsayiRtpa 96 
                  +d++v+ggG+ g vvA+RL+edp+ svlvleag++  +      + ++a++ +d + ++  ++ p+++lngr l  p+G+tlGG+s++N ++ i +++
   EEA20382.1  16 YDYIVVGGGTSGLVVASRLTEDPAVSVLVLEAGSNRVSDPriAVPGLAASTYFDPEFDWCLTSVPQENLNGRSLAEPRGRTLGGSSAINLGMVIYPSQ 113
                  79********************************9987777666667788889999****************************************** PP

  GMC_oxred_N  97 adldeWeeeaglegwssdevlpafkkvetaqale.............sdlhgvdgrlgvtekgkeespln.kallkaaeelGlpvprdlngk.hqcGv 179
                  ad+d Wee  g++gw+++ +  +++k+ t + +                ++g +g+++v + g+   p++ + + ka e+lG +++ d  ++  + ++
   EEA20382.1 114 ADIDAWEEL-GNDGWNWKSISHYMRKSQTLTLPSdeikqelslqyidPAVQGQTGPINV-SFGNGPFPAFnQTWPKAFENLGHKLTGDPMSGvAKGAF 209
                  ********9.******************9888889999*****9999999*********.88888888766*************88887777699999 PP

  GMC_oxred_N 180 cllgv.tcrtgarqstarawLrpal.erpnleiltgakaekiil...egrkkravGVeasdkkgtvkrlvvaakevvvaaGalnsPqlLqrSGlGkae 272
                  c  g    +t ar+ +  a+  + + +rpnl+++t++ +eki+l    +++  a+GV + +k+g  ++++ a++ev++aaG++++P+lL++SG+G+ +
   EEA20382.1 210 CGPGSiHPETRARSHAGVAYYNEEVaKRPNLRVVTEVLVEKILLekdGDKDAIATGVLYATKDGV-QKTFSANREVILAAGSIKTPHLLELSGIGNCA 306
                  999995677888999999999999889*****************877567889***********9.999***************************** PP

  GMC_oxred_N 273 hLkevgvdvvvdlp.vGknLqdH 294
                   L+++g++++++   vG+nLq H
   EEA20382.1 307 LLESHGIKPIINNAnVGENLQEH 329
                  **********************9 PP

>> GMC_oxred_C  GMC oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.4   0.0   9.7e-34   1.7e-30       1     144 []     464     604 ..     464     604 .. 0.87

  Alignments for each domain:
  == domain 1  score: 106.4 bits;  conditional E-value: 9.7e-34
                  ----EEEEESTT-TCCEEEEE--TT-SHHHHHHHHHHHHHHHHHCTSGGGTTEECCEECCCTTTTS.HCHHCHHCHHCHHHHH-EE-S--B-TT-B-S CS
  GMC_oxred_C   1 PesrGrvtlsssdptgaplidpnylsdprdlaalvealkaarkilaaaaldvleeeltpgaaeetsdaavesdealekfvkeavltsaHplGtcrMGa 98 
                  P+srG+v+l+s+d ++ p++dp ++s+p dl+  ++ ++++  ++ +++l  l +   ++   ++s+ +++ ++  +++ +++++  +H++Gt++M +
   EEA20382.1 464 PFSRGTVHLASPDTKALPVFDPAFFSHPLDLELHARHVRWLETLAWSEPLASLLKTDGRRL--QNSSPDMSLET-ARELARDRIVCHYHVVGTAAMLP 558
                  89**********************************************8644444444443..33444444444.45799999999************ PP

                  TCGCBSB-TTSBBTT-CSEEE-SGGGSSS--SS-THHHHHHHHHHH CS
  GMC_oxred_C  99 dpkdsVVDsdlrvhgvdnLrVvDaSvfPsapganptltilalAeka 144
                  +++ +VVDs+l+v+g++nLrVvDaS++P +p +n+++ ++a+Aeka
   EEA20382.1 559 REQGGVVDSHLKVYGTQNLRVVDASIIPIIPRGNTQAIVFAVAEKA 604
                  ********************************************97 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.2   4.8e-06    0.0085       1      41 [.      17      58 ..      17      67 .. 0.84
   2 !   10.3   0.0   0.00015      0.27     139     204 ..     222     293 ..     180     315 .. 0.77

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 4.8e-06
                   SEEEE--SHHHHHHHHHHHHTTT.-EEEEESSSGGGSGGGG- CS
  FAD_binding_2  1 DviViGsGlAGLaAAleaaeaGl.kvavvekeqefggataws 41
                   D iV+G+G +GL+ A +++e  + +v+v+e ++++ +   ++
     EEA20382.1 17 DYIVVGGGTSGLVVASRLTEDPAvSVLVLEAGSNRVSDPRIA 58
                   88******************9999*******99876655555 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00015
                    HHHHHHHHHHHHHHTCT.EEEEESEEEEEEEECTT....EEEEEEEEETTTTCEEEEEES.EEEE-----GG CS
  FAD_binding_2 139 tghallarlvesarkag.vdfqerteadeLivedg....rvtGavvenpesgrevrirak.avvlatgGfgr 204
                      ha +a   e++ k++ +++ ++  +++++ e++     + + v+   ++g + ++ a+  v+la+g ++ 
     EEA20382.1 222 RSHAGVAYYNEEVAKRPnLRVVTEVLVEKILLEKDgdkdAIATGVLYATKDGVQKTFSANrEVILAAGSIKT 293
                    455556666666767777**************85557788888888889999999999999*******9987 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.6   0.2   2.1e-07   0.00037       1      29 [.      20      49 ..      20      53 .. 0.92

  Alignments for each domain:
  == domain 1  score: 20.6 bits;  conditional E-value: 2.1e-07
                   EE--SHHHHHHHHHHHCC.TEEEEEE-SSS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLaka.gfdvlllekrd 29
                   +vG+G sGlv A++L+++  ++vl+le+++
     EEA20382.1 20 VVGGGTSGLVVASRLTEDpAVSVLVLEAGS 49
                   8****************9788******986 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.1   0.0   0.00079       1.4       1      31 [.      19      49 ..      19      54 .. 0.93
   2 !    9.4   0.0   0.00031      0.56      78     150 ..     222     305 ..     209     317 .. 0.72

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00079
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEkgn 31
                 i++G+G  Gl +a  l +    ++l+lE g+
   EEA20382.1 19 IVVGGGTSGLVVASRLTEDPAVSVLVLEAGS 49
                 89**************************994 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.00031
  Pyr_redox_3  78 lsrkealeYlrevaksfelpiklfeeVesvkked..egfevet.....ske....tyeA.kkviiAtGefdkPnklnipGeeklv 150
                   s + +++Y +evak+ +l++ ++  Ve++  e+  ++  + t     +k+    t++A ++vi+A+G  + P++l+ +G   ++
   EEA20382.1 222 RSHAGVAYYNEEVAKRPNLRVVTEVLVEKILLEKdgDKDAIATgvlyaTKDgvqkTFSAnREVILAAGSIKTPHLLELSGIG-NC 305
                  45677899*********************966441144555542332233223346666468****************9997.44 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   3.8e-06    0.0069      17      49 ..      15      47 ..       5      52 .. 0.90
   2 ?   -1.0   0.0      0.48   8.6e+02     107     132 ..     234     262 ..     226     275 .. 0.73

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 3.8e-06
                EEEEEEE--SHHHHHHHHHHHHCTTS-EEEEES CS
        Thi4 17 esDvvivGaGssGLtaayylakkpdlkvailer 49
                + D ++vG+G+sGL  a  l+++p + v++le+
  EEA20382.1 15 QYDYIVVGGGTSGLVVASRLTEDPAVSVLVLEA 47
                5699***************************96 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.48
                 HHTSTTEEEEESEEEEEEEEET..B.TEE CS
        Thi4 107 vlqlanvkllnavaveDlivre..g.egv 132
                 v +++n+++++ v ve +++ +  + + +
  EEA20382.1 234 VAKRPNLRVVTEVLVEKILLEKdgDkDAI 262
                 66789999999999999988764423444 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   5.8e-06      0.01       1      30 [.      17      49 ..      17      77 .. 0.93
   2 ?   -0.6   0.0      0.44   7.8e+02     156     201 ..     235     289 ..     200     305 .. 0.60

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 5.8e-06
                EEEEECTSHHHHHHHHHHHHTT...EEEEESSS CS
         DAO  1 dvviiGGGiiGlstAyeLarrg...Vtllekgd 30
                d +++GGG  Gl +A  L++ +   V++le+g+
  EEA20382.1 17 DYIVVGGGTSGLVVASRLTEDPavsVLVLEAGS 49
                789*****************9999******984 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.44
                 HHHTT-EEEESECEEEE..EEEE....TCEEEEE.EECT.EEE.E.EEEE.EEE--G CS
         DAO 156 aealGveilegtevtgl..eeed....gkvwgve.rttp.gen.d.aada.vVnaaG 201
                 a++   +++++  v+++  e +d      ++gv    t+ g + + +a+  v++aaG
  EEA20382.1 235 AKRPNLRVVTEVLVEKIllE-KDgdkdAIATGVLyA-TKdGVQkTfSANReVILAAG 289
                 44445566666666665432.332332223444444.44477743433446999999 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.1   5.1e-06    0.0092       1      35 [.      17      50 ..      17      57 .. 0.91

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 5.1e-06
  Lycopene_cycl  1 DvvviGaGpAglslAarlteakpglkvvlieasps 35
                   D +v+G+G  gl +A rl  + p+++v+++ea+ +
     EEA20382.1 17 DYIVVGGGTSGLVVASRL-TEDPAVSVLVLEAGSN 50
                   789***************.789**********976 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.0   0.00057         1       2     175 ..      17      49 ..       4      61 .. 0.60
   2 ?    1.7   0.0      0.07   1.3e+02      89     121 ..     269     303 ..     202     327 .. 0.67

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00057
                  SEEEE--SHHHHHHHHHHHHHTS-EEEEETTHCHHHCSHHHHCHHHHHHHHHHHHHHHHHCHHHHCCCCHCCTCEEEEESCEEEEETEEECTCEEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2   2 dvvviGgGpAGlaaaltlaqagakvtlvelegtclnggcllskallgvaedaeiasevvkklnqgielllgeevvkidpgkkkvklekkkegdeekia 99 
                  d++v+GgG  Gl +a +l +                                                                              
   EEA20382.1  17 DYIVVGGGTSGLVVASRLTE------------------------------------------------------------------------------ 36 
                  45555555555555555555.............................................................................. PP

                  ESEEEE---EEE-BCTCTTC.TTBEECCSECHHHHHHCCSS-TSEEEEES-SHHHHHHHHHHHHH.T-EEEEEESSS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxx RF
  Pyr_redox_2 100 ydklvlAtGssprdlgipGvaenvgklvrtldsaealklkllpkrivvvGgGyiGvElAaalakl.gkevtlveard 175
                                                                                    ++ v ++ea++
   EEA20382.1  37 ----------------------------------------------------------------DpAVSVLVLEAGS 49 
                  ................................................................3344444444443 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.07
                  EEECTCEEEEEE.SEEEE---E..EE-BCTCTTC.T CS
                  xxxxxxxxxxxx.xxxxxxxxx..xxxxxxxxxxxx RF
  Pyr_redox_2  89 kkkegdeekiay.dklvlAtGs..sprdlgipGvae 121
                  ++k+g ++++ +  +++lA Gs  +p++l + G   
   EEA20382.1 269 ATKDGVQKTFSAnREVILAAGSikTPHLLELSGI-G 303
                  2334555666665789999999888888888888.2 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0     7e-05      0.13       2      33 ..      17      49 ..      16      61 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 7e-05
                 SEEEE--SHHHHHHHHHH.HHTT--EEEE-SSS CS
  HI0933_like  2 dviviGgGaAGlmaAisa.akrgkrVlllekak 33
                 d iv+GgG +Gl  A ++ ++   +Vl+le+++
   EEA20382.1 17 DYIVVGGGTSGLVVASRLtEDPAVSVLVLEAGS 49
                 78***************9778899******986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (612 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       302  (0.0168442); expected 358.6 (0.02)
Passed bias filter:                      293  (0.0163422); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.59u 0.27s 00:00:00.86 Elapsed: 00:00:00.45
# Mc/sec: 4060.36
//
Query:       EEA20383.1  [L=190]
Description: hypothetical protein PMAA_042290 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (190 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       338  (0.0188521); expected 358.6 (0.02)
Passed bias filter:                      294  (0.016398); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.45
# Mc/sec: 1278.16
//
Query:       EEA20384.1  [L=440]
Description: toxin biosynthesis protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.7e-13   50.2   0.2    7.3e-13   49.6   0.2    1.3  1  Abhydrolase_6  Alpha/beta hydrolase family
    3.9e-06   26.3   0.0    6.1e-06   25.7   0.0    1.2  1  Hydrolase_4    Serine aminopeptidase, S33
    0.00037   20.2   0.0     0.0013   18.4   0.0    1.9  2  Abhydrolase_1  alpha/beta hydrolase fold
  ------ inclusion threshold ------
      0.029   14.7   0.7      0.061   13.6   0.7    1.4  1  PTH2           Peptidyl-tRNA hydrolase PTH2


Domain annotation for each model (and alignments):
>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.6   0.2   1.6e-16   7.3e-13       4     219 ..      57     378 ..      54     379 .. 0.55

  Alignments for each domain:
  == domain 1  score: 49.6 bits;  conditional E-value: 1.6e-16
                    E--GC.....GCHHHH.....HHHHCCT.....CEEEEE--TTST..........S-GGCS--HHH.CHHHHHHHCCTT..TTSEEEEEETCHHH. CS
  Abhydrolase_6   4 lHGagssassWlvapL.....aallaag.....vhvlapDlpGhG..........rsdpppldled.ladlaalldelaagggpvvlvGHSlGGa. 77 
                    +H+ g++++ +   pL     a    +g     +  ++ D+ ++G          ++dp+++d+++ l++l +l +++   ++p+v+vGHS+GGa 
     EEA20384.1  57 AHANGFPKELYE--PLwediyAQSQKHGfrirsI--WMADAAHQGesgvinenmlGNDPSWFDHSRdLLHLINLKRDEM--PRPIVGVGHSMGGAq 146
                    688887777774..55554453333333555448..*****99996666666666669999999775666688888886..*************95 PP

                    ...HHHHHHHCC..EE.EEES-................................----TTTS----TTHHHHHHTT-CCCCHCCH..S-HSCCCCH CS
  Abhydrolase_6  78 ...lalaaaplalvvg.vlldp.................pp.............talpagllaaalelllallallrllawlsre..plprlflad 137
                       l+l ++p +++ + vlldp                  p             ++  a+   + ++++ +++ +++l++w++++   lp   ++d
     EEA20384.1 147 ltyLSL-LQPRLFH-SlVLLDPviqsestqspdkfegrfVPmntilsthrrdiwPSRKAAAEGFQRSPFYKAWNPRVLDRWVKYGlrELPTVAHPD 240
                    553333.3444454.35*****99988888766665555113333333322222233333344444444444446666899977766555466666 PP

                    HH...C...CCCHCHCCCGHH.....................................HHCCHHCHTT......CCHHTT-TTGC.EEECTT-C.. CS
  Abhydrolase_6 138 ed...a...daawrarlarla.....................................allaglgllp......aaawadlpvpl.lvlggeDp.. 181
                    e+   a   d +++ + +r++                                             ++       + ++++++++ ++++g+    
     EEA20384.1 241 ESkykAskdDKPVTLATTRHQevftfsrpnydydranekpanlyetpdlkpdgpntfpF-------YRmepnfiFSQLPRVRPSVlYIFAGQSFmc 329
                    66654154555555555555566676667777777777777776665555443333211.......111111224466666666644445444432 PP

                    ........HHHHCHHCCCH..STTEEET.CE...SSS-HHHHSH.HHHHH CS
  Abhydrolase_6 182 ........lvprllerlla..qagarlp.vvlpgaGHlphleep.devae 219
                            +    + + +   +a+ r++ v++ + GHl+ + e+ +++a 
     EEA20384.1 330 tpsmmqdkMDNTGIGQGGSggVAVGRVKsVYFQDKGHLLAQ-EAvAQCAH 378
                    22211111333334444444434444437********9999.55588886 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.7   0.0   1.4e-09   6.1e-06      36     139 ..      90     199 ..      77     227 .. 0.74

  Alignments for each domain:
  == domain 1  score: 25.7 bits;  conditional E-value: 1.4e-09
  Hydrolase_4  36 alDhrGhGrse....gkrghvpsfddyvdDlaafvekvkeehpelplfllGhSmGGliallyllrypdkvaglilsaPalkikaklkappllkl...l 126
                  + D+  +G+s+    +  g  ps+ d+ +Dl  +++  + ++  +p++ +GhSmGG+  + + l +p+ ++ l+l  P+++ ++  ++ ++      +
   EEA20384.1  90 MADAAHQGESGvineNMLGNDPSWFDHSRDLLHLINLKR-DEMPRPIVGVGHSMGGAQLTYLSLLQPRLFHSLVLLDPVIQSESTQSPDKFEGRfvpM 186
                  56666677777777677788899********99996555.566668**********************9***********998765233333333334 PP

  Hydrolase_4 127 lkllgkllpklqv 139
                  +++l++  +++ +
   EEA20384.1 187 NTILSTHRRDIWP 199
                  4444444444444 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.0   2.9e-07    0.0013      74     115 ..     134     178 ..      80     186 .. 0.86
   2 ?   -1.8   0.0      0.44     2e+03      24      51 ..     254     282 ..     242     303 .. 0.74

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 2.9e-07
                    SEEEEEETHHHHHHHHHHHHHGGGEEEEEEESE...CSSCCHHHH CS
  Abhydrolase_1  74 kltlvGhSmGGmialayaaeyperVkalvllga...idpaaslie 115
                    +++ vGhSmGG++ +++ ++ p   ++lvll++   +++  s+++
     EEA20384.1 134 PIVGVGHSMGGAQLTYLSLLQPRLFHSLVLLDPviqSESTQSPDK 178
                    56679****************************776555555554 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.44
                    HHHHT.TSEEEEEEETTSTTSSSTTTGB. CS
  Abhydrolase_1  24 aLakd.gfdvillDlrGvgySspapacin 51 
                    +La + +++v+++  ++++y ++   + n
     EEA20384.1 254 TLATTrHQEVFTFSRPNYDYDRANEKPAN 282
                    45555688999999999999887666554 PP

>> PTH2  Peptidyl-tRNA hydrolase PTH2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.7   1.4e-05     0.061      15      53 ..     369     410 ..     363     421 .. 0.72

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 1.4e-05
                 HHHHHHHHHHHHHHHHHHHHHH...CHHHHHHHHHHT.TTSE CS
        PTH2  15 kGkiaaqcahAavalvkkllkes..nekellkeWeee.gqkk 53 
                 +++ +aqcahAav+++ k l++   +e+++ k+W  + + +k
  EEA20384.1 369 AQEAVAQCAHAAVEFFGKELQRWkeEEAAFQKTWSGKsQVEK 410
                 57889***********98877653333577789976634444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (440 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       323  (0.0180155); expected 358.6 (0.02)
Passed bias filter:                      289  (0.0161191); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 3029.25
//
Query:       EEA20385.1  [L=322]
Description: alkaline dihydroceramidase Ydc1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.3e-105  352.5   9.7   1.6e-105  352.3   9.7    1.0  1  Ceramidase       Ceramidase
  ------ inclusion threshold ------
       0.14   11.5   7.5       0.72    9.1   0.5    2.1  2  Peptidase_U4     Sporulation factor SpoIIGA
       0.17   11.5   4.2        1.2    8.8   0.1    2.3  2  DUF4131          Domain of unknown function (DUF4131)


Domain annotation for each model (and alignments):
>> Ceramidase  Ceramidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  352.3   9.7  2.7e-109  1.6e-105       1     263 []      19     310 ..      19     310 .. 0.98

  Alignments for each domain:
  == domain 1  score: 352.3 bits;  conditional E-value: 2.7e-109
  Ceramidase   1 gyWgpvtStidwCEenYvvtpyiAEfvNTlsnllfillallgiynaakkklekrfllaylglalvGlgSalFHaTLkyetQllDelsmiyatalvlyav 99 
                 gyW+pvtSt++wCEe+Y++tpy+AE+vN+++n+lf+ll+++g+ n++k++++k+f +a+ g+++vG+gS+lFH+TLky++Ql+Delsmiy+t+l++ya 
  EEA20385.1  19 GYWSPVTSTLNWCEEDYYATPYSAEIVNSVTNFLFMLLGIKGVLNVRKHGHDKVFEIAFYGYLIVGMGSFLFHSTLKYPMQLVDELSMIYTTCLMCYAS 117
                 8************************************************************************************************** PP

  Ceramidase 100 fsekksrstrvllgvlltalavvvtllylvlkepvlhqvafalltvlvllrsiyliekkv...............................dksdeaak 167
                 fs+++s st+++l+v+l+ lav++tl+y++l++p++hq+a+allt++v++rs+y +e  +                               +++d ++ 
  EEA20385.1 118 FSYSRSSSTKIFLAVTLAGLAVFITLYYHYLQDPAFHQNAYALLTTVVVFRSMYNMEVALrpkwrksreedrlarerkglpvlskerqeyeNTRDLKTL 216
                 ********************************************************9777999999999999999999***********998899**** PP

  Ceramidase 168 kevkklallgliifllgfliWnlDnlfCstltrlrraiglplgvllelHgwWHiltgigayilivlleylrvekkgkedselelawpsrlgvlPev 263
                 k +++++++gl++fl gf+iWnlDn+fC+tl+++r++iglp+g++le+HgwWH++tgigay++iv++++lr+ ++++++ +++l+wp+++  +Pe+
  EEA20385.1 217 KIMWSMVIYGLAMFLGGFAIWNLDNVFCTTLRSWRQRIGLPWGIFLEGHGWWHLMTGIGAYLYIVWGIWLRHILNKEQE-DYTLIWPHTW-NFPEI 310
                 ******************************************************************************7.8*******99.68876 PP

>> Peptidase_U4  Sporulation factor SpoIIGA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   1.3   0.00099       5.9      16      73 ..     109     166 ..      43     192 .. 0.45
   2 ?    9.1   0.5   0.00012      0.72      90     143 ..     222     295 ..     206     304 .. 0.68

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.00099
  Peptidase_U4  16 yllLlltakllklkikklrlllaAllGalyvvlvlflpklesillsillkilvsllmv 73 
                   +++L++ a +   + +  +++la +l++l v+++l++  l++++++  +++l+ +++v
    EEA20385.1 109 TTCLMCYASFSYSRSSSTKIFLAVTLAGLAVFITLYYHYLQDPAFHQNAYALLTTVVV 166
                   2334444444444444444444444444444444444322222222222222222222 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.00012
  Peptidase_U4  90 llfylvsfllgGilfa.lsyll..................lkskn...llvlllgalvaylllk.llvkiikkkkkk 143
                   +++y ++++lgG++++ l  ++                  l   +   +++l+ g+++ +++++ ++++ i +k+++
    EEA20385.1 222 MVIYGLAMFLGGFAIWnLDNVFcttlrswrqriglpwgifL---EghgWWHLMTGIGAYLYIVWgIWLRHILNKEQE 295
                   57899999999965541444447666665555555555444...0566*********99999998888888666554 PP

>> DUF4131  Domain of unknown function (DUF4131)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   0.1    0.0002       1.2      15      70 ..     111     166 ..     103     204 .. 0.75
   2 ?    3.0   1.5     0.012        69       6      63 ..     221     301 ..     215     310 .. 0.59

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0002
     DUF4131  15 llllllllllrrrprrrvllllllllllallgfalrapqpnandlsqllesgqevi 70 
                 +l++++ + + r  + +++l+++l+ l++++ ++++++q +a + + ++ + + v+
  EEA20385.1 111 CLMCYASFSYSRSSSTKIFLAVTLAGLAVFITLYYHYLQDPAFHQNAYALLTTVVV 166
                 344555555555899999*************************9999998655555 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.012
     DUF4131   6 alvllalllllllllllllrr.........rprrrv.................llllllllllallgfalrapqpnandlsqll 63 
                 + v+ +l+++l  ++++  +            +r++                 +++++++l ++++ ++ + ++++++d+  ++
  EEA20385.1 221 SMVIYGLAMFLGGFAIW--NLdnvfcttlrS-WRQRiglpwgifleghgwwhlMTGIGAYLYIVWGIWLRHILNKEQEDYTLIW 301
                 44444444455444444..334699988852.3333244555555555544447777777777777777777777777766655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (322 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       832  (0.0464053); expected 358.6 (0.02)
Passed bias filter:                      442  (0.0246528); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.47
# Mc/sec: 2074.34
//
Query:       EEA20386.1  [L=972]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
     0.0033   16.4  10.7     0.0033   16.4  10.7    5.1  5  Spc7          Spc7 kinetochore protein
  ------ inclusion threshold ------
        1.2    9.2   6.6       0.35   11.0   1.2    2.7  2  Sigma70_r1_1  Sigma-70 factor, region 1.1
        5.2    7.2   0.0        5.2    7.2   0.0    5.6  5  ATG16         Autophagy protein 16 (ATG16)


Domain annotation for each model (and alignments):
>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.2      0.19   1.1e+03     218     245 ..     355     382 ..     349     403 .. 0.57
   2 ?   -4.8  15.7       1.6   9.4e+03     164     253 ..     426     518 ..     422     555 .. 0.57
   3 !    2.7   5.1     0.008        48     204     281 ..     607     685 ..     590     725 .. 0.69
   4 !   16.4  10.7   5.4e-07    0.0033     164     275 ..     743     856 ..     732     875 .. 0.80
   5 ?    0.5   7.3     0.038   2.3e+02     200     252 ..     913     965 ..     902     972 .] 0.67

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.19
        Spc7 218 kkkelaelqeqleeleekieelkeqkse 245
                 ++++++el+++l e++++++    +  e
  EEA20386.1 355 FMNKISELEAELREISSELAGSIRREME 382
                 4555555666665555555444333333 PP

  == domain 2  score: -4.8 bits;  conditional E-value: 1.6
        Spc7 164 eldellpeleeekaeleeelek....lqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaea 253
                  +++++ + e+e+a+l+ el +    ++++++ +es   + Le+  ++++++ ++ ++++ ++ el+  le+ + k+ e ++ k+++e+ + + 
  EEA20386.1 426 DIERIKRAAEQERAQLKVELSQkwqeERSRRAACES-HVQILENQVQQFRAQRVDNSNLSSKTRELEVALEDTRRKLLEERQLKDNFEDLLTAM 518
                 455566666666665555544310003334444333.355677777778888888888888888888888888877776666666665544422 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.008
        Spc7 204 lreelaelkaeieekkkel.aelqeqleeleekieelkeqkseleeeiaeaervleeckgwsesevsrlkeevkaleel 281
                  re+la+  +++e++++ l + l++ l++++ +  e +++ + le e+ +a++v   +k   e ev++l+ee ++l + 
  EEA20386.1 607 SRESLADRVKDVEAQRDALhKALKSLLDRQAWQARENEKRLTILEIELTKAQDVGSPRKLGYEREVRNLREEINHLRRR 685
                 4666666666666666554134555566666677777777777777777777777777777777777777777766554 PP

  == domain 4  score: 16.4 bits;  conditional E-value: 5.4e-07
        Spc7 164 eldellpeleeekaeleeeleklqeaaeelesid.keeLe.elreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaervleec 260
                 +++    +le+ + +l++e+e+ ++++ + e+++ +e+L+ ++r++l++++a  +++ + +a+ +++ + ++++i+e++++ ++le+ +  a++  e +
  EEA20386.1 743 NMQITSSALESAYHQLQAEMESAEAESWSPEDMNrNENLAgQVRQQLETNNALRRRLAEAIAKGEREQKMSASRINEMQTRLRKLEDTLVDAQHHSEDE 841
                 55666778999999********99999998998877888658999999999999999999999999999999999999888888888888888888888 PP

        Spc7 261 kgwsesevsrlkeev 275
                     e+ev++lke++
  EEA20386.1 842 MTKHEEEVRALKESH 856
                 888888888888764 PP

  == domain 5  score: 0.5 bits;  conditional E-value: 0.038
        Spc7 200 eLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiae 252
                 +++el ++l++++ e+ee  +++++ q +++el+++ +e+  q ++le++i +
  EEA20386.1 913 KVKELEKALRDADFEMEEVVQRMNKAQIEVAELQSDRDEALRQTRRLEAAILA 965
                 56677777777777777777777777777777777777777777777777643 PP

>> Sigma70_r1_1  Sigma-70 factor, region 1.1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.4      0.26   1.5e+03      31      72 ..     809     850 ..     790     858 .. 0.69
   2 ?   11.0   1.2   5.9e-05      0.35      20      72 ..     912     962 ..     908     971 .. 0.77

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.26
                   CSS--HHHHHHHHHHHHCCT-EEE-SS-.........S-SSS CS
  Sigma70_r1_1  31 ddeldseqiediiemLedmgIdvveeaededellleeeaeda 72 
                   ++ +++  i ++++ L ++   +v+ +  +++++++ e+e  
    EEA20386.1 809 EQKMSASRINEMQTRLRKLEDTLVDAQHHSEDEMTKHEEEVR 850
                   566778888888888888888888888866666644444333 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 5.9e-05
                   EEHHHHHHHGCCSS--HHHHHHHHHHHHCCT-EEE-SS-..........S-SSS CS
  Sigma70_r1_1  20 LtyeEindaLpddeldseqiediiemLedmgIdvveeaededell.leeeaeda 72 
                   +  +E+++aL d +    ++e++++ +++++I+v e + d de l ++   e+a
    EEA20386.1 912 VKVKELEKALRDAD---FEMEEVVQRMNKAQIEVAELQSDRDEALrQTRRLEAA 962
                   56788889998444...479*******************999988666665555 PP

>> ATG16  Autophagy protein 16 (ATG16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   0.0   0.00087       5.2      67     119 ..     347     402 ..     297     407 .. 0.79
   2 ?   -0.0  12.8      0.15   8.7e+02      78     178 ..     433     533 ..     412     537 .. 0.71
   3 ?    3.6   6.8     0.011        67      22     116 ..     606     705 ..     590     728 .. 0.57
   4 ?    4.8  15.2    0.0049        29      31     137 ..     748     854 ..     741     864 .. 0.70
   5 ?    3.5   6.9     0.012        71     124     178 ..     906     960 ..     901     967 .. 0.76

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.00087
       ATG16  67 q...snskqsakiqsleqklaqlreelaelyksrgelaqrllelneelqkleeklk 119
                 +   sn++  +ki++le++l ++ +ela + ++  el++ + + + e + + ++ +
  EEA20386.1 347 PasgSNADFMNKISELEAELREISSELAGSIRREMELEDLVERFQLESHNDANRRT 402
                 04457888899****************************99999888887766655 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 0.15
       ATG16  78 sleqklaqlreelaelyksrgelaqrllelneelqkleeklkedeerlaeleaeraaletklkdreeelrekeklvqdlqDElsaLqlqlnqaEeklrk 176
                 + eq++aql+ el++  ++         +  + l+ + ++ ++++    +l+++ ++le +l+d + +l e ++l +++ D l+a++++l+q+  +++ 
  EEA20386.1 433 AAEQERAQLKVELSQKWQEERSRRAACESHVQILENQVQQFRAQRVDNSNLSSKTRELEVALEDTRRKLLEERQLKDNFEDLLTAMRVELEQLRNERDH 531
                 567777777777765544444444444444455555555666666677778888888888888888888888888888888888888888887777665 PP

       ATG16 177 le 178
                  +
  EEA20386.1 532 FR 533
                 55 PP

  == domain 3  score: 3.6 bits;  conditional E-value: 0.011
       ATG16  22 qaynrLldrtsaleaenaklekaaasaks.sksskksakekeasasq..........snskqsakiqsleqklaqlreelaelyksrgelaqrllelne 109
                 +    L+dr++  ea++ +l+ka +s    +++++      +++++            + + s +    e ++  lree   l ++  e  ++  + ++
  EEA20386.1 606 ESRESLADRVKDVEAQRDALHKALKSLLDrQAWQA------RENEKRltileieltkAQDVGSPRKLGYEREVRNLREEINHLRRRADEALEQKWQCEK 698
                 55567999999999999999999888887433333......2222222345567777445555555556666666666666666655554444444443 PP

       ATG16 110 elqklee 116
                  l  l+ 
  EEA20386.1 699 GLGGLKM 705
                 3333333 PP

  == domain 4  score: 4.8 bits;  conditional E-value: 0.0049
       ATG16  31 tsaleaenaklekaaasakssksskksakekeasasqsnskqsakiqsleqklaqlreelaelyksrgelaqrllelneelqkleeklkede....erl 125
                 +sale+   +l+++++sa+++++s ++ +++e  a q     ++++++ ++++ +l e  a+  +++  +a+r++e+++ l+kle++l   +     ++
  EEA20386.1 748 SSALESAYHQLQAEMESAEAESWSPEDMNRNENLAGQ----VRQQLETNNALRRRLAEAIAKGEREQKMSASRINEMQTRLRKLEDTLVDAQhhseDEM 842
                 6789999999999999999977777677777766666....7788888888888888888888888888888888888888888887655430000344 PP

       ATG16 126 aeleaeraalet 137
                  + e+e++al++
  EEA20386.1 843 TKHEEEVRALKE 854
                 444455555444 PP

  == domain 5  score: 3.5 bits;  conditional E-value: 0.012
       ATG16 124 rlaeleaeraaletklkdreeelrekeklvqdlqDElsaLqlqlnqaEeklrkle 178
                 ++a+le ++++le++l+d + e++e  + +++ q E++ Lq     a  + r+le
  EEA20386.1 906 SVAKLEVKVKELEKALRDADFEMEEVVQRMNKAQIEVAELQSDRDEALRQTRRLE 960
                 6788888888888888888888888888888888888888877766666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (972 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1960  (0.10932); expected 358.6 (0.02)
Passed bias filter:                      592  (0.0330191); expected 358.6 (0.02)
Passed Vit filter:                        81  (0.00451782); expected 17.9 (0.001)
Passed Fwd filter:                        34  (0.00189637); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 1.24u 0.32s 00:00:01.56 Elapsed: 00:00:00.55
# Mc/sec: 5333.53
//
Query:       EEA20387.1  [L=483]
Description: C6 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.3e-61  205.9   0.6    1.1e-60  205.5   0.6    1.0  1  Fungal_trans_2  Fungal specific transcription factor domain
  ------ inclusion threshold ------
       0.16   11.1   0.0       0.28   10.3   0.0    1.3  1  HDA2-3          Class II histone deacetylase complex subunits


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  205.5   0.6   1.2e-64   1.1e-60       2     379 ..      83     478 ..      82     481 .. 0.91

  Alignments for each domain:
  == domain 1  score: 205.5 bits;  conditional E-value: 1.2e-64
  Fungal_trans_2   2 lldyyldnvapllspvpessnpfrkvllplalsnkallhallalsafhlqskgpkds...lereakrykslalkelqealaelsstlsrnekykd 93 
                     ll++++++ ++++s+++  +   +++++p+al++++ll+a +alsa+h +++++ ++      ++ r++ ++l++++ +l++ s++ s     + 
      EEA20387.1  83 LLHHFISDASRVTSCHSGMQQDICQMIVPMALQTPSLLYATMALSAIHIEALNNHSGtvkAAPDIARLMARSLEHFRLELQDSSRKGS-----DV 172
                     89***********************************************8888777788889**************************.....88 PP

  Fungal_trans_2  94 iLaaiLllcsieissgd..vsdwrvhLeaatsliksrggskasssslsskarfllrifayldilssttlgrgpsfpseeyekllenkkeesdsgl 186
                     +La+  +lc++ei sg   +  wr h e+a++l+++  +s  s +      + l r++ ++  l+++  +  +++  e +++ +++  +++ ++l
      EEA20387.1 173 LLATARTLCLAEIHSGAiqPNTWRAHVEGAKALMSTKTPS--SYTPATGFRKYLDRWYRSIVALTALNGN--GPPIGETWAHTDTT-VSDDPDYL 262
                     88888************66566******************..9999999********9998777777777..999999********.9******* PP

  Fungal_trans_2 187 dplmGcsnslilliseisrLarekrsarkd...............seleplsileeaseleqrll.swkprssd....lepdldeterasslskd 261
                     d+++G+  +l +++ ei++La+++++ + +               +++ +++i e+a +le+ +l  ++ ++++    + p  +e+ +++s+++ 
      EEA20387.1 263 DDYWGFTVHLASIFREIGALAWQRHQDNITtsqfktlepikkeeeEKDVESNIDEQAARLEKSVLgLIARYNQNaglvFYPGVKEKLSEESIREF 357
                     ******************************************9999999999*************888888887222234444555555555544 PP

  Fungal_trans_2 262 l..telfrlaaliylyrlvlglppsspevqelvkkllellellpsspv..aiasLlWplFiaGceavdeddRdfvrrrleele.qsrlgnvrrar 351
                     +   e+f+++ali+++r+v+++p++spevq +vk++l++++++ +s++   +++L+ plF+ Gcea  e dR+ ++++l  l   +r+ nv + +
      EEA20387.1 358 MlcNEAFQHTALIHIHRRVRKVPATSPEVQYSVKRILACTSQIAPSSGlsPWVMLTTPLFTGGCEALGE-DREAFKQLLTLLHnTTRIPNVLQSL 451
                     568*****************************************8888788899999************.9************999********* PP

  Fungal_trans_2 352 qvleevWrrrddgeekidWrdvmekkgw 379
                     ++le+ W++   ++++ dW ++++++  
      EEA20387.1 452 EFLEKYWAHGA-QNKNEDWSHFLDRMSF 478
                     ***********.6779******988765 PP

>> HDA2-3  Class II histone deacetylase complex subunits 2 and 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   3.1e-05      0.28     214     290 ..     130     207 ..     122     208 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 3.1e-05
                 HHHHHH----------EEEEEETTSHHHHHHHHT.S-TT-HHHHHHHHHHHHHHTT.TTT---TTTHHHHHTTTGGGHH CS
      HDA2-3 214 sveslrtqnrkknklpiirlvpinSieHvkLcfk.kdedepeylekvissivvlrd.evGkLpddllpiyeqklkylsh 290
                 ++e l ++  +++ +p i  +  +S eH++L+ + ++++  + l   ++ + +l + + G ++++    + +  k l++
  EEA20387.1 130 HIEALNNHSGTVKAAPDIARLMARSLEHFRLELQdSSRKGSDVLLA-TARTLCLAEiHSGAIQPNTWRAHVEGAKALMS 207
                 79999999999999**99999*************656666666655.566666665379*******9999999999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (483 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       562  (0.0313459); expected 358.6 (0.02)
Passed bias filter:                      481  (0.026828); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 3336.92
//
Query:       EEA20388.1  [L=479]
Description: Vacuolar ATP synthase subunit H, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.6e-78  262.0   0.0      1e-77  261.6   0.0    1.2  1  V-ATPase_H_N  V-ATPase subunit H
    8.5e-37  125.8   0.0    3.8e-36  123.7   0.0    2.2  2  V-ATPase_H_C  V-ATPase subunit H


Domain annotation for each model (and alignments):
>> V-ATPase_H_N  V-ATPase subunit H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  261.6   0.0   1.1e-81     1e-77       1     315 []       7     352 ..       7     352 .. 0.97

  Alignments for each domain:
  == domain 1  score: 261.6 bits;  conditional E-value: 1.1e-81
  V-ATPase_H_N   1 svlqelankirarkipWegyvrsqliseedlkliksldkakkeqraklldedgpqyvklll.......nLlskl.skedtlqyiLvlidDllsedks 89 
                   ++l++l+n+irar+ipW+g+vr++ i+e++l+ ik++dk++ ++r++ +++d + y++ll        ++l+++ +++d++qyiLvl +Dl+++ ++
    EEA20388.1   7 TYLNSLQNNIRARPIPWDGAVRAGNITEDQLRKIKAVDKVRTQERKQAVEADLNGYTTLLAgnppdvkSVLESAsRRTDIVQYILVLAADLINDVPA 103
                   5899********************************************************9*******99999999********************* PP

  V-ATPase_H_N  90 rvelflslakkeeqdpwkpflkllnrqddfivllalrllakllvqgkkksnklv..esaLnrllqlLssqlssstnevieiavrllqellrtkeyRe 184
                   +++++ s  + + ++ + pfl+ l++++d+i+lla+ +l++l++++  +++++   e+aL++l+++L ++++++++++++i+v+ +++llr+k  Re
    EEA20388.1 104 LASALIS--HPNPYNAFLPFLRNLTNPEDPIPLLASSFLTNLVSTALVSDQTTDaeEEALPQLYTYLANLTKNQDSGLQDIGVQGFSALLRNKVARE 198
                   ***9999..888999****************************9998877775577***************************************** PP

  V-ATPase_H_N 185 lfve..adgvstlisilr........................stvanstrvgiQlqYqvllclWlLsFekkiaeelvkkk.elipllvdilrdsvKE 254
                   lf++  ++++ +l+ ilr                        ++++    vg+Ql+Y+vll++W+LsFe  +++e +++k ++i l++++lr s+KE
    EEA20388.1 199 LFWKqrSETLDPLMGILRtaaggkdngsinlatsaatssirtADISIGGGVGLQLLYHVLLVIWQLSFEGSLVGEELQSKyDIIELYTQLLRLSPKE 295
                   *****************************************9888999***************************999999**************** PP

  V-ATPase_H_N 255 KvtRvilatlrNllekaeksskelaavmvqvkllkllenLeerkfsDeditedleyLkeeL 315
                   K+tR++latl  ll +++    +l++v+ +v+l++ll+nL+ r+ +D+d+ edl+ L++ L
    EEA20388.1 296 KTTRLLLATLNILLVANR----TLLPVATFVRLPALLSNLSGRHLTDPDLLEDLQSLTDLL 352
                   **********99999998....59*********************************9876 PP

>> V-ATPase_H_C  V-ATPase subunit H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0      0.66   5.9e+03      39      93 ..      35      89 ..      29      92 .. 0.56
   2 !  123.7   0.0   4.3e-40   3.8e-36       2     117 .]     359     477 ..     358     477 .. 0.95

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.66
  V-ATPase_H_C 39 knfkllkkLiklleeskdktvlavalnDigelvkllp.egkkvleklkaKekimel 93
                  ++ + +k++ k+  ++++k+ +   ln  + l+   p + k+vle+ + ++ i+++
    EEA20388.1 35 DQLRKIKAVDKVR-TQERKQAVEADLNGYTTLLAGNPpDVKSVLESASRRTDIVQY 89
                  5555555555555.344455555555555554443332777777777777777765 PP

  == domain 2  score: 123.7 bits;  conditional E-value: 4.3e-40
  V-ATPase_H_C   2 ltsfdeYlaElesgkLewspvHksekFWkenaekl.eeknfkllkkLikll..eeskdktvlavalnDigelvkllpegkkvleklkaKekimelle 95 
                   +t+fdeY+aEl+sg+L+wsp+H++  FW+en +++ ee++ +l kkL++++  + ++dk+vla+a+nD+g+lvk++pe +  lekl+ K+++mel++
    EEA20388.1 359 QTTFDEYAAELQSGHLRWSPPHRNPAFWRENTRRIlEEERGALPKKLAEIIakSWENDKQVLAIACNDVGNLVKEVPERRMQLEKLGLKTRVMELMT 455
                   79********************************999999***********65335679************************************** PP

  V-ATPase_H_C  96 hedeevkyeALkavqkllvqnw 117
                   ++de+v++e+L+av ++l +++
    EEA20388.1 456 DRDESVRWESLRAVGEWLRYSF 477
                   *****************99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (479 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       625  (0.0348597); expected 358.6 (0.02)
Passed bias filter:                      548  (0.030565); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.25s 00:00:00.84 Elapsed: 00:00:00.42
# Mc/sec: 3401.49
//
Query:       EEA20389.1  [L=64]
Description: hypothetical protein PMAA_042350 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (64 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       335  (0.0186848); expected 358.6 (0.02)
Passed bias filter:                      251  (0.0139997); expected 358.6 (0.02)
Passed Vit filter:                         9  (0.00050198); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.39u 0.30s 00:00:00.69 Elapsed: 00:00:00.56
# Mc/sec: 345.37
//
Query:       EEA20390.1  [L=767]
Description: M protein repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.8e-41  140.9  12.9    1.8e-41  140.9  12.9    6.9  4  TMF_TATA_bd   TATA element modulatory factor 1 TATA binding
    5.4e-21   74.4  15.5    5.4e-21   74.4  15.5    9.6  9  TMF_DNA_bd    TATA element modulatory factor 1 DNA binding
    1.2e-05   25.6   5.5    1.2e-05   25.6   5.5    5.3  2  ATG16         Autophagy protein 16 (ATG16)
    0.00057   20.4  11.1    0.00057   20.4  11.1    7.3  7  BST2          Bone marrow stromal antigen 2
     0.0012   17.8  18.6     0.0012   17.8  18.6    5.4  4  Spc7          Spc7 kinetochore protein
     0.0049   16.4  86.0        0.2   11.1  32.8    4.4  4  Golgin_A5     Golgin subfamily A member 5
  ------ inclusion threshold ------
       0.18   10.4  70.6       0.79    8.3  11.4    4.1  4  AAA_13        AAA domain
        1.4    7.9   5.1        0.3   10.1   0.4    2.2  3  MCR_C         Methyl-coenzyme M reductase operon protein C
        3.1    7.6  11.7      0.038   13.8   1.3    3.4  4  DASH_Duo1     DASH complex subunit Duo1
        3.1    5.2  94.1        0.2    9.2   8.1    3.1  3  DUF3584       Protein of unknown function (DUF3584)
        4.7    6.5  77.4      0.043   13.2   5.2    4.4  4  DUF4407       Domain of unknown function (DUF4407)
          7    5.9  95.3       0.94    8.8  15.9    5.2  5  GAS           Growth-arrest specific micro-tubule binding


Domain annotation for each model (and alignments):
>> TMF_TATA_bd  TATA element modulatory factor 1 TATA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0       1.4     2e+03      35      82 ..      57     104 ..      33     105 .. 0.78
   2 ?    0.8   9.3      0.37   5.5e+02      19      81 ..     234     296 ..     225     300 .. 0.91
   3 ?   -0.7  17.5       1.1   1.6e+03      28     103 ..     432     508 ..     408     515 .. 0.75
   4 !  140.9  12.9   1.2e-44   1.8e-41       2     114 ..     652     764 ..     651     765 .. 0.98

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 1.4
  TMF_TATA_bd  35 lerleaerdeareeivklmkeneelkelkkeleelekeleelqeryet 82 
                  l + ++ r +    +v+ ++   ++++ ++  e +e++++++ +++++
   EEA20390.1  57 LDSGSQPRTSKDLSVVEHISAESNQESGSEMPEIVESQVADVATKEDA 104
                  555666677777778888888888888999999999999999998875 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.37
  TMF_TATA_bd  19 seirrlEgElaslkeelerleaerdeareeivklmkeneelkelkkeleelekeleelqerye 81 
                   +  +lE +++ ++ + +r ea+ ++a+e + + ++ + +l++  +e + l++ +eel++++ 
   EEA20390.1 234 RRTAKLERDVSDAEARAKRAEASEKKAQESLNSQSRASKDLESITAERNALTSTVEELKSQLA 296
                  5556899***************************************************99875 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 1.1
  TMF_TATA_bd  28 laslkeelerleae.rdeareeivklmkeneelkelkkeleelekeleelqeryetlLellGeksEeveELraDvaD 103
                  +++ ++e++r ea  r+++re  ++  k  +el+++++++++l ++l+e ++++++l +   + +Ee +  r+++aD
   EEA20390.1 432 MEKERDEIARKEADlRRKTREVNIRAKKAEDELETANETIADLDRSLQETKQQLQKLQQRVEKSEEELNAVRKELAD 508
                  34445666666554266677777888899999999999999999999999999999999999999999988888888 PP

  == domain 4  score: 140.9 bits;  conditional E-value: 1.2e-44
  TMF_TATA_bd   2 sstssagpsvqlverlsseirrlEgElaslkeelerleaerdeareeivklmkeneelkelkkeleelekeleelqeryetlLellGeksEeveELra 99 
                  +st++agpsvqlver+s+++rrlE+E a++k+eler++a+rdear+e+v+lm+e+e+++++++++eele++++el++ry+t+LellGeksE+v+EL+a
   EEA20390.1 652 VSTVGAGPSVQLVERMSATVRRLESERAATKDELERITAQRDEARKEVVELMRESEDKRKAESRIEELESQVAELDQRYQTTLELLGEKSEQVDELQA 749
                  799*********************************************************************************************** PP

  TMF_TATA_bd 100 DvaDlKemykeqveq 114
                  D+aDlK++y+e+v++
   EEA20390.1 750 DIADLKKIYRELVDS 764
                  *************86 PP

>> TMF_DNA_bd  TATA element modulatory factor 1 DNA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.4      0.76   1.1e+03      12      27 ..     151     166 ..     129     178 .. 0.58
   2 !   74.4  15.5   3.6e-24   5.4e-21       2      74 .]     182     254 ..     181     254 .. 0.98
   3 ?   -0.2   4.7      0.68     1e+03      28      70 ..     267     309 ..     255     313 .. 0.59
   4 ?   -1.4   3.4       1.6   2.5e+03      34      63 ..     313     342 ..     304     357 .. 0.62
   5 ?   -2.5   7.9       3.6   5.4e+03      47      72 ..     362     387 ..     335     389 .. 0.62
   6 ?    2.7   1.8     0.082   1.2e+02      40      74 .]     427     461 ..     421     461 .. 0.91
   7 !   10.0  10.2   0.00046      0.68      31      74 .]     467     510 ..     462     515 .. 0.93
   8 ?   -0.9   6.8       1.1   1.7e+03      24      70 ..     698     730 ..     668     733 .. 0.55
   9 ?    2.5   1.2     0.095   1.4e+02       3      26 ..     733     756 ..     731     761 .. 0.84

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.76
  TMF_DNA_bd  12 eqIaqLmeEGekLskk 27 
                 e+I++L++ ++ L+k+
  EEA20390.1 151 ERIDALQSKLKYLAKE 166
                 3444444444444433 PP

  == domain 2  score: 74.4 bits;  conditional E-value: 3.6e-24
  TMF_DNA_bd   2 slekklkeKDeqIaqLmeEGekLskkelklnntikkLrkknkelekeikelkkkleklekeleeleerlkeae 74 
                 s+ek+l eKDe+Ia L+eEG+kLsk+el++++ ikkLr++++e++k+ ++lk++++kle++++  e+r+k+ae
  EEA20390.1 182 SIEKQLSEKDERIALLLEEGQKLSKTELDNRTVIKKLRQQLAESNKQETDLKRRTAKLERDVSDAEARAKRAE 254
                 89*********************************************************************98 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 0.68
  TMF_DNA_bd  28 elklnntikkLrkknkelekeikelkkkleklekeleeleerl 70 
                 + + ++ + +  ++ + l+++++elk++l++ +   e  e+r+
  EEA20390.1 267 QSRASKDLESITAERNALTSTVEELKSQLARAVTRAEAAESRA 309
                 3444445555556666666777777777776666666666665 PP

  == domain 4  score: -1.4 bits;  conditional E-value: 1.6
  TMF_DNA_bd  34 tikkLrkknkelekeikelkkkleklekel 63 
                  +   +  + ele ++++ k + e +e++l
  EEA20390.1 313 VVEHSKRRITELEDDLSSAKIERELSEEKL 342
                 555556667788888888876666555554 PP

  == domain 5  score: -2.5 bits;  conditional E-value: 3.6
  TMF_DNA_bd  47 keikelkkkleklekeleeleerlke 72 
                    +elk++ + le+++e+l++r++e
  EEA20390.1 362 LLEAELKSEQSVLESKMESLRSRAEE 387
                 23467889999999999999999875 PP

  == domain 6  score: 2.7 bits;  conditional E-value: 0.082
  TMF_DNA_bd  40 kknkelekeikelkkkleklekeleeleerlkeae 74 
                 + ++ +eke +e  +k ++l ++  e + r+k+ae
  EEA20390.1 427 SRLNGMEKERDEIARKEADLRRKTREVNIRAKKAE 461
                 567899**************************998 PP

  == domain 7  score: 10.0 bits;  conditional E-value: 0.00046
  TMF_DNA_bd  31 lnntikkLrkknkelekeikelkkkleklekeleeleerlkeae 74 
                  n+ti  L+  ++e+ +++++l++++ek+e+el+  +++l+ +e
  EEA20390.1 467 ANETIADLDRSLQETKQQLQKLQQRVEKSEEELNAVRKELADKE 510
                 689**********************************9999886 PP

  == domain 8  score: -0.9 bits;  conditional E-value: 1.1
  TMF_DNA_bd  24 LskkelklnntikkLrkknkelekeikelkkkleklekeleeleerl 70 
                    + +++++                ++ ++++e+le++++el +r+
  EEA20390.1 698 EVVELMRESED--------------KRKAESRIEELESQVAELDQRY 730
                 33333333333..............3444456666666666665555 PP

  == domain 9  score: 2.5 bits;  conditional E-value: 0.095
  TMF_DNA_bd   3 lekklkeKDeqIaqLmeEGekLsk 26 
                 ++++l eK eq+++L++   +L+k
  EEA20390.1 733 TLELLGEKSEQVDELQADIADLKK 756
                 578999*********998777765 PP

>> ATG16  Autophagy protein 16 (ATG16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1  31.9      0.63   9.5e+02      22     180 ..     364     505 ..     346     527 .. 0.40
   2 !   25.6   5.5     8e-09   1.2e-05      68     163 ..     663     754 ..     617     760 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.63
       ATG16  22 qaynrLldrtsaleaenaklekaaasaks...........sksskksakekeasasq.................snskqsakiqsleqklaqlreelae 92 
                 +a  +L   +s le++ ++l+++a++++s           +               q                  +s+  ++++ +e+++ ++    a+
  EEA20390.1 364 EA--ELKSEQSVLESKMESLRSRAEEVSSstagetqakllR---------------QietlqtqyavasenwqgIESSLISRLNGMEKERDEIARKEAD 445
                 33..3333444444444444444444443222111111110...............0111233344444444442222223333333444444444444 PP

       ATG16  93 lyksrgelaqrllelneelqkleeklkedeerlaeleaeraaletklkdreeelrekeklvqdlqDElsaLqlqlnqaEeklrklekE 180
                 l ++  e + r +++++el++ +e++   +++l+e +++ ++l++++++ eeel+  +k                            E
  EEA20390.1 446 LRRKTREVNIRAKKAEDELETANETIADLDRSLQETKQQLQKLQQRVEKSEEELNAVRK----------------------------E 505
                 44444444444444444444444444444444444444444444444444444433333............................3 PP

  == domain 2  score: 25.6 bits;  conditional E-value: 8e-09
       ATG16  68 snskqsakiqsleqklaqlreelaelyksrgelaqrllelneelqkleeklkedeerlaeleaeraaletklkdreeelrekeklvqdlqDElsaL 163
                   ++ sa++  le+++a++++el+    +r e  + ++el+ e +++++     e+r++ele+++a+l ++++   e l ek + v++lq +++ L
  EEA20390.1 663 LVERMSATVRRLESERAATKDELERITAQRDEARKEVVELMRESEDKRK----AESRIEELESQVAELDQRYQTTLELLGEKSEQVDELQADIADL 754
                 4567899*************************************99976....689**********************************999877 PP

>> BST2  Bone marrow stromal antigen 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.9      0.64   9.6e+02      56      88 ..     134     166 ..     126     169 .. 0.79
   2 ?    0.7   6.0      0.55   8.3e+02      44      85 ..     211     253 ..     182     259 .. 0.64
   3 ?    5.0   6.6     0.025        38      27      89 ..     268     335 ..     252     337 .. 0.74
   4 ?    0.3   8.5      0.73   1.1e+03      12      86 ..     339     415 ..     336     419 .. 0.78
   5 !   20.4  11.1   3.8e-07   0.00057      22      90 ..     446     514 ..     430     515 .. 0.87
   6 !    9.2   6.0    0.0012       1.7      10      86 ..     662     734 ..     659     738 .. 0.82
   7 ?    1.2   0.1      0.39   5.8e+02      63      80 ..     739     756 ..     736     764 .. 0.85

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.64
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        BST2  56 kekaqsqkqqakvqelqgeikkLnqkLqdaeae 88 
                 +++a + ++q+ ++e  + i  L+ kL+   +e
  EEA20390.1 134 EHQAAESRWQEDMHEYIERIDALQSKLKYLAKE 166
                 567777888999999999999999999977665 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.55
                 HHHH.HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        BST2  44 nqtv.vtLkasLekekaqsqkqqakvqelqgeikkLnqkLqda 85 
                 n+tv ++L++ L + + q+ + +++  +l++++ + + + + a
  EEA20390.1 211 NRTViKKLRQQLAESNKQETDLKRRTAKLERDVSDAEARAKRA 253
                 3443156777777777777777777777777776666655555 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.025
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.....HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
        BST2  27 tqaqeslreaeaqaatcnqtvvtLkasLek.....ekaqsqkqqakvqelqgeikkLnqkLqdaeaev 89 
                  +a + l++  a+ ++  +tv++Lk+ L +     e a+s+ q + v+  ++ i++L++ L  a+ e 
  EEA20390.1 268 SRASKDLESITAERNALTSTVEELKSQLARavtraEAAESRAQAEVVEHSKRRITELEDDLSSAKIER 335
                 57889999999***************998711111444555566667888999********9998775 PP

  == domain 4  score: 0.3 bits;  conditional E-value: 0.73
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH..HHHHHHHHHHHHHHHHHHHHHHHHHH CS
        BST2  12 eqecrnvtrlLerqLtqaqeslreaeaqaatcnqtvvtLkasLekekaq..sqkqqakvqelqgeikkLnqkLqdae 86 
                 e+++r   r L+ +L + +e+ +  ea+  + ++++++ ++sL     +  s  + +   +l ++i++L+ +   a+
  EEA20390.1 339 EEKLRREIRSLQDNLGREKENAHLLEAELKSEQSVLESKMESLRSRAEEvsSSTAGETQAKLLRQIETLQTQYAVAS 415
                 7888999999*************************999999997654431134445666778889999988766555 PP

  == domain 5  score: 20.4 bits;  conditional E-value: 3.8e-07
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC CS
        BST2  22 LerqLtqaqeslreaeaqaatcnqtvvtLkasLekekaqsqkqqakvqelqgeikkLnqkLqdaeaeve 90 
                 L r+ ++ +   ++ae++  t n+t+ +L  sL++ k q qk q++v++ ++e++   ++L d+e+ ve
  EEA20390.1 446 LRRKTREVNIRAKKAEDELETANETIADLDRSLQETKQQLQKLQQRVEKSEEELNAVRKELADKEKSVE 514
                 555555556667899*************************************************99987 PP

  == domain 6  score: 9.2 bits;  conditional E-value: 0.0012
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        BST2  10 raeqecrnvtrlLerqLtqaqeslreaeaqaatcnqtvvtLkasLe.kekaqsqkqqakvqelqgeikkLnqkLqdae 86 
                 +  ++ + + r Le + + ++++l++  aq     + vv+L+   e k ka     +++++el+ ++++L+q+ q ++
  EEA20390.1 662 QLVERMSATVRRLESERAATKDELERITAQRDEARKEVVELMRESEdKRKA-----ESRIEELESQVAELDQRYQTTL 734
                 556777888899*******************99999999998644404444.....589*************988765 PP

  == domain 7  score: 1.2 bits;  conditional E-value: 0.39
                 HHHHHHHHHHHHHHHHHH CS
        BST2  63 kqqakvqelqgeikkLnq 80 
                 ++ ++v elq +i++L++
  EEA20390.1 739 EKSEQVDELQADIADLKK 756
                 57789***********97 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6  30.0       2.7     4e+03     128     291 ..     141     304 ..     126     309 .. 0.75
   2 ?    3.1   7.6     0.024        36     155     216 ..     350     412 ..     339     419 .. 0.78
   3 !   17.8  18.6   7.8e-07    0.0012     137     246 ..     418     523 ..     411     547 .. 0.79
   4 !    8.8  14.4   0.00044      0.66     149     246 ..     665     761 ..     661     767 .] 0.62

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 2.7
        Spc7 128 dWYeWRmqllegLkegleenlegleedkelLekqeeel...dellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkela 223
                  W e + + +e + + l+++l+ l +++++ +++ + +    ++ ++l+e+ +++   le+ q+ ++  e  +++ +++lr++lae +++   +k+++a
  EEA20390.1 141 RWQEDMHEYIERI-DALQSKLKYLAKEAAESARDAASAakpGSIEKQLSEKDERIALLLEEGQKLSK-TELDNRTVIKKLRQQLAESNKQETDLKRRTA 237
                 5555555555555.34666666666666655555444422245777777777777777777666443.3445599************************ PP

        Spc7 224 elqeqleeleekieelkeqkseleeeiaeaervleeckgwsesevsrlkeevkaleeltgwkivslsg 291
                 +l++++ + e++ + ++++ ++++e ++++ r  +  +++++ e ++l+++v++l++++  +++++++
  EEA20390.1 238 KLERDVSDAEARAKRAEASEKKAQESLNSQSRASKDLESITA-ERNALTSTVEELKSQLARAVTRAEA 304
                 ****************************88888887777776.6699*********999999988875 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.024
        Spc7 155 kelLekqeeeldellpeleeekaeleeeleklqeaaeelesid.keeLeelreelaelkaeie 216
                 +++L +++e+++ l  el++e++ le+++e+l+++aee++s++  e  ++l +++++l+++++
  EEA20390.1 350 QDNLGREKENAHLLEAELKSEQSVLESKMESLRSRAEEVSSSTaGETQAKLLRQIETLQTQYA 412
                 57889999999*****************************98844444566667777776665 PP

  == domain 3  score: 17.8 bits;  conditional E-value: 7.8e-07
        Spc7 137 legLkegleenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleek 235
                  +g++++l ++l+g+e+++++++++e+ l +   e++ + ++ e+ele+ +e  ++l+     +L+e++++l++l++ +e+ ++el+ ++++l+++e++
  EEA20390.1 418 WQGIESSLISRLNGMEKERDEIARKEADLRRKTREVNIRAKKAEDELETANETIADLD----RSLQETKQQLQKLQQRVEKSEEELNAVRKELADKEKS 512
                 589*****************************99999999999999999999665544....4788888888888888888888888888888888888 PP

        Spc7 236 ieelkeqksel 246
                 +e+  +qk e 
  EEA20390.1 513 VESFWAQKLEE 523
                 87655555432 PP

  == domain 4  score: 8.8 bits;  conditional E-value: 0.00044
        Spc7 149 egleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqksel 246
                 e + +  ++Le++++  ++ l++++++++e ++e+ +l +++e+ +   + ++eel +++ael++ ++   + l e+ eq++el+++i++lk+ ++el
  EEA20390.1 665 ERMSATVRRLESERAATKDELERITAQRDEARKEVVELMRESED-KRKAESRIEELESQVAELDQRYQTTLELLGEKSEQVDELQADIADLKKIYREL 761
                 45555556666666666666666666666666666666665554.44456667777777777777777777777777777777777777776665555 PP

>> Golgin_A5  Golgin subfamily A member 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.2   7.6    0.0043       6.4      67     175 ..     125     239 ..      92     247 .. 0.67
   2 !   11.1  32.8   0.00014       0.2      32     214 ..     257     443 ..     253     457 .. 0.75
   3 !    5.8  21.4    0.0056       8.4      49     156 ..     429     533 ..     402     536 .. 0.76
   4 !    8.6   8.2   0.00078       1.2      40     135 ..     662     756 ..     649     765 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0043
   Golgin_A5  67 nqqieqlrtelqdleaqqqaeaeslreqlqeleeqleeerkakee......veaelerlkeelryleee...lvrskatlqsrikdrekeieklrnqlt 156
                   q e+lr+e q  e++ q++++++ e++  l+++l+   k+  e        a+  +++++l+   e    l ++ ++l +   d  + i+klr+ql+
  EEA20390.1 125 PDQFEELRAEHQAAESRWQEDMHEYIERIDALQSKLKYLAKEAAEsardaaSAAKPGSIEKQLSEKDERialLLEEGQKLSKTELDNRTVIKKLRQQLA 223
                 57899************************99999886433333220000002233333444444444332222344445555555777899******98 PP

   Golgin_A5 157 tkslsssseselesRlkqL 175
                  +++   +e++l  R  +L
  EEA20390.1 224 ESNK---QETDLKRRTAKL 239
                 6544...567777776555 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00014
   Golgin_A5  32 egsgeeglesstalsaeldelkqerdllreelqklnqqieqlrtelqdleaqqqaea.eslreqlqeleeqleeerkake....eveaelerlkeelry 125
                 e++++e+l+s+ ++s++l+++++er++l++ +++l++q+ +  t  +  e+++qae+ e+++ +++ele+ l++ + ++e    +++ e+++l+++l +
  EEA20390.1 257 EKKAQESLNSQSRASKDLESITAERNALTSTVEELKSQLARAVTRAEAAESRAQAEVvEHSKRRITELEDDLSSAKIERElseeKLRREIRSLQDNLGR 355
                 667899***************************************9*********973678899******99977666651111445555556666666 PP

   Golgin_A5 126 leeelvrskatlqsrikdrekeieklrnqlttkslsssseselesRlkqLtesLiqKQtvl..EalsteknslvlQLeRleqqikevqsea 214
                  +e+ +   a+l+s+    e+++e+lr+     + sss+  e +++l    e+L    + +  E+ +   +sl+  L+ +e++  e+  + 
  EEA20390.1 356 EKENAHLLEAELKSEQSVLESKMESLRSRAE--EVSSSTAGETQAKLLRQIETLQTQYA-VasENWQGIESSLISRLNGMEKERDEIARKE 443
                 6666665555565555556666666665543..45667888999999999999954444.335999999*************999987754 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.0056
   Golgin_A5  49 ldelkqerdllreelqklnqqieqlrtelqdleaqqqaeaeslreqlqeleeqleeerkakeeveaelerlkeelryleeelvrskatlqsri.kdrek 146
                 l+ +++     r+e+++ +  +++   e++   ++++ e e+++e +++l+  l+e +++ +++++ +e+ +eel+++++el  + ++++s   ++ e+
  EEA20390.1 429 LNGMEK----ERDEIARKEADLRRKTREVNIRAKKAEDELETANETIADLDRSLQETKQQLQKLQQRVEKSEEELNAVRKELADKEKSVESFWaQKLEE 523
                 334444....45677777788888888887778899999*******************************************98888888765155688 PP

   Golgin_A5 147 eieklrnqlt 156
                 e  + r+q++
  EEA20390.1 524 ERARWREQVA 533
                 8888888886 PP

  == domain 4  score: 8.6 bits;  conditional E-value: 0.00078
   Golgin_A5  40 esstalsaeldelkqerdllreelqklnqqieqlrtelqdleaqqqaeaeslreqlqeleeqleeerkakeeveaelerlkeelryleeelvrska 135
                 ++ +++sa +  l++er ++++el++ + q ++ r+e+ +l + ++++ ++++ +++ele+q++e  ++ +++ + l +++e+++ l+ +    k+
  EEA20390.1 662 QLVERMSATVRRLESERAATKDELERITAQRDEARKEVVELMR-ESEDKRKAESRIEELESQVAELDQRYQTTLELLGEKSEQVDELQADIADLKK 756
                 5566778888889999999999999999999999999888854.4588888899999999999987777777777777788888877777665554 PP

>> AAA_13  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2  16.9    0.0089        13     317     447 ..     133     265 ..     120     273 .. 0.74
   2 ?    8.3  11.4   0.00053      0.79     365     469 ..     265     369 ..     261     372 .. 0.90
   3 ?    8.1  18.8   0.00059      0.88     326     463 ..     367     516 ..     362     523 .. 0.59
   4 ?    7.5   3.4   0.00091       1.4     377     459 ..     663     757 ..     653     764 .. 0.50

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.0089
      AAA_13 317 safeedkeelkaeaealeeqLkglqraleaKrkepfksvelesvkakiesikklvaeinelia...khNekvanleeekeeakkklelhlveeleseld 412
                  + + + +  ++ + +  e++++lq++l+   ke ++s+    ++ak  si+k+++e  e ia   +  +k ++ e +  ++ kkl+++l+e+ ++e d
  EEA20390.1 133 AEHQAAESRWQEDMHEYIERIDALQSKLKYLAKEAAESARDAASAAKPGSIEKQLSEKDERIAlllEEGQKLSKTELDNRTVIKKLRQQLAESNKQETD 231
                 33334444444455555566777777777777777777777777777777777777777777722234667788888999*****************75 PP

      AAA_13 413 eykkkykklekaieklekelkeeeaelkkleeeik 447
                  +k+  +kle++++++e+++k +ea  kk++e  +
  EEA20390.1 232 -LKRRTAKLERDVSDAEARAKRAEASEKKAQESLN 265
                 .************************9999998765 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.00053
      AAA_13 365 esikklvaeineliakhNekvanleeekeeakkklelhlveeleseldeykkkykklekaieklekelkeeeaelkkleeeikeLekqlrdekpaaeei 463
                 +s + + ++++ + a+ N+ ++ +ee k++++ ++ + +++e +++ +  ++ ++++++   +l  ++ e e   +kl+ ei+ L+ +l  ek+ a  +
  EEA20390.1 265 NSQSRASKDLESITAERNALTSTVEELKSQLARAVTRAEAAESRAQAEVVEHSKRRITELEDDLSSAKIERELSEEKLRREIRSLQDNLGREKENAHLL 363
                 556677888999999*************************999999998898999999888889999999999999*********************** PP

      AAA_13 464 nkeLka 469
                 + eLk+
  EEA20390.1 364 EAELKS 369
                 ***986 PP

  == domain 3  score: 8.1 bits;  conditional E-value: 0.00059
      AAA_13 326 lkaeaealeeqLkglqraleaKrkepfksvelesvkakie...............sikklvaein.eliakhNek...vanleeekeeakkklelhlv. 404
                 lk+e ++le+++++l+++ e+     + +          +                ++++ + i+  li++ N +    +++++++++++ k +   + 
  EEA20390.1 367 LKSEQSVLESKMESLRSRAEEVSSSTAGET---------QakllrqietlqtqyaVASENWQGIEsSLISRLNGMekeRDEIARKEADLRRKTREVNIr 456
                 233333333333333333332222222211.........122222333333333322222222222456666655111456777777777777776544 PP

      AAA_13 405 .eeleseldeykkkykklekaieklekelkeeeaelkkleeeikeLekqlrdekpaaeei 463
                  +++e+el++ ++++++l++++++++++l++ +++++k eee ++ +k+l d+++++e +
  EEA20390.1 457 aKKAEDELETANETIADLDRSLQETKQQLQKLQQRVEKSEEELNAVRKELADKEKSVESF 516
                 489999999999*****************************************9999875 PP

  == domain 4  score: 7.5 bits;  conditional E-value: 0.00091
      AAA_13 377 liakhNekvanleeekeeakkklelhlv..eeleseldeyk...kkykklekaieklekelkeeeaelk.......kleeeikeLekqlrdekpa 459
                 l+++  ++v +le+e+++ k++le+  +   e+++e+ e++   ++++k+e  ie+le +++e  ++ +       ++ e++ eL++ + d k++
  EEA20390.1 663 LVERMSATVRRLESERAATKDELERITAqrDEARKEVVELMresEDKRKAESRIEELESQVAELDQRYQttlellgEKSEQVDELQADIADLKKI 757
                 55555666666666666666666665543334444444433333444444444444444444444444400000004455555666555555554 PP

>> MCR_C  Methyl-coenzyme M reductase operon protein C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   0.1         4   5.9e+03     181     217 ..     294     329 ..     279     355 .. 0.54
   2 ?   -3.2   0.1       2.4   3.5e+03     190     238 ..     355     403 ..     329     414 .. 0.61
   3 ?   10.1   0.4    0.0002       0.3     169     248 ..     461     538 ..     452     544 .. 0.88

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 4
       MCR_C 181 glGriahrlrkeeeiealdelveeveevldkkreela 217
                 +l r + r   + e +a  e+ve+ ++ + +  ++l+
  EEA20390.1 294 QLARAVTRAEAA-ESRAQAEVVEHSKRRITELEDDLS 329
                 445555554333.333334444444444444444443 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.4
       MCR_C 190 rkeeeiealdelveeveevldkkreelakDpllvsparvkkeieeqvee 238
                 r++e+ + l+   ++ ++vl++k e+l + +  vs+++  ++  + +++
  EEA20390.1 355 REKENAHLLEAELKSEQSVLESKMESLRSRAEEVSSSTAGETQAKLLRQ 403
                 4455555556556666666666666666666665555444443333333 PP

  == domain 3  score: 10.1 bits;  conditional E-value: 0.0002
       MCR_C 169 leevpgaeayvgglGriahrlrkeeeiealdelveeveevldkkreelakDpllvsparvkkeieeqveeieevlsPapi 248
                  +e+++a++ +++l r  + +++  ++++l++ ve+ ee l+  r+ela+   +v++   +k  ee+ +  e+v sP p 
  EEA20390.1 461 EDELETANETIADLDRSLQETKQ--QLQKLQQRVEKSEEELNAVRKELADKEKSVESFWAQKLEEERARWREQVASPPPF 538
                 56678899999999999998775..699******************************9999999999999999999886 PP

>> DASH_Duo1  DASH complex subunit Duo1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.1       7.8   1.2e+04      14      31 ..     213     230 ..     212     238 .. 0.70
   2 ?   -2.6   0.1       3.1   4.7e+03      12      42 ..     342     372 ..     335     389 .. 0.61
   3 ?   -3.0   0.0       4.3   6.4e+03      54      69 ..     406     421 ..     400     424 .. 0.76
   4 ?   13.8   1.3   2.5e-05     0.038       7      42 ..     462     497 ..     458     501 .. 0.90

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 7.8
   DASH_Duo1  14 evienviesLkkaksnie 31 
                 +vi++++++L +++++  
  EEA20390.1 213 TVIKKLRQQLAESNKQET 230
                 578888888888886555 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 3.1
   DASH_Duo1  12 inevienviesLkkaksniervketvestnt 42 
                 +++ i +++++L + k+n + ++  ++s ++
  EEA20390.1 342 LRREIRSLQDNLGREKENAHLLEAELKSEQS 372
                 4444555555555555555555555555444 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 4.3
   DASH_Duo1  54 tehtqrllldpeWkga 69 
                 t +tq  + +++W+g 
  EEA20390.1 406 TLQTQYAVASENWQGI 421
                 5578888889999985 PP

  == domain 4  score: 13.8 bits;  conditional E-value: 2.5e-05
   DASH_Duo1   7 eqLrkinevienviesLkkaksniervketvestnt 42 
                 ++L++ ne+i +++ sL+++k+++++++++ve++++
  EEA20390.1 462 DELETANETIADLDRSLQETKQQLQKLQQRVEKSEE 497
                 679999**************************9875 PP

>> DUF3584  Protein of unknown function (DUF3584)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5  43.4    0.0017       2.5     301     533 ..     126     363 ..     123     369 .. 0.76
   2 ?    0.7  29.5     0.048        71     368     525 ..     365     527 ..     351     535 .. 0.79
   3 ?    9.2   8.1   0.00013       0.2     652     744 ..     666     755 ..     654     765 .. 0.70

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0017
     DUF3584 301 delkeaidelnqelsaakaklaakeselealeeqkkkyedadieklkadldql..psirseleeleeeldaltekhqdvqekydrrkqkikeeleeele 397
                 d+++e ++e + + s  ++++++  ++++al+++ k   ++ +e+++  ++++  +si+++l+e +e++++l+e+ q++ +    ++ +ik+ +++  e
  EEA20390.1 126 DQFEELRAEHQAAESRWQEDMHEYIERIDALQSKLKYLAKEAAESARDAASAAkpGSIEKQLSEKDERIALLLEEGQKLSKTELDNRTVIKKLRQQLAE 224
                 89******************************9999999999999877666553379***********************9999999999999999999 PP

     DUF3584 398 klkerleaireekdrlkaaieealealesqlrkqleaqkeelneeekelesrlselklrldsatat.eEeleqieeadealekaqeelek.....aeae 490
                  +k++++  r +++  + + +++  a +++  +++ ++  + +    +  + l++    +++ t t eE++ q++ a+ + e+a++++++     ++ +
  EEA20390.1 225 SNKQETDLKRRTAKLERDVSDAEARAKRAEASEKKAQESLNSQ---SRASKDLESITAERNALTSTvEELKSQLARAVTRAEAAESRAQAevvehSKRR 320
                 9999999999888888888888888888877755444444333...33444444444444444444166677888888888888766544111115556 PP

     DUF3584 491 vealqaeeeqlrkkrdeadealqkaerrleqlrqaleeleeql 533
                   +l++++  ++ +r+  +e+l+++ r+l++   + +e  + l
  EEA20390.1 321 ITELEDDLSSAKIERELSEEKLRREIRSLQDNLGREKENAHLL 363
                 6778999999999999999999999999999877766655555 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.048
     DUF3584 368 daltekhqdvqekydrrkqkikeeleeeleklkerleaireekdrlkaaieealealesqlrkqle...aqkeelneeekelesrlselklrldsatat 463
                 + l +++  +++k++ +++ ++e       + +++l  + e+ +++ a+++e+ + +es+l ++l+   ++  e++++e++l+++  e + r+++a  +
  EEA20390.1 365 AELKSEQSVLESKMESLRSRAEEVSSSTAGETQAKLLRQIETLQTQYAVASENWQGIESSLISRLNgmeKERDEIARKEADLRRKTREVNIRAKKAEDE 463
                 4567778888999999999999999999999999988999999999***************99975111566677888889999999999999999888 PP

     DUF3584 464 eEe.leqieeadealekaqeelekaeaevealqaeeeqlrkk.rdeadealqkaerrleqlrqa 525
                  E+ +e i+  d+ l++ +++l+k +++ve+ ++e++++rk+  d+ +   +  +++le+ r++
  EEA20390.1 464 LETaNETIADLDRSLQETKQQLQKLQQRVEKSEEELNAVRKElADKEKSVESFWAQKLEEERAR 527
                 88735679999**********************9999999872566666666677778877766 PP

  == domain 3  score: 9.2 bits;  conditional E-value: 0.00013
     DUF3584 652 nardtlerlqnekesekdklekaiaerkqqaeeqlqkldaqlkqleeqqkaaleelkedlseerlekkakwqevvgeldeqlaelkkaieaar 744
                     t++rl++e+ + kd+le+ i++++++a++++++l  + +  +++ ++ +eel++++ e   ++ +   e+ ge++eq++el++ i+  +
  EEA20390.1 666 RMSATVRRLESERAATKDELER-ITAQRDEARKEVVELMRESED-KRKAESRIEELESQVAELD-QRYQTTLELLGEKSEQVDELQADIADLK 755
                 5556777888888888888876.445566777777777777665.4455566777778887777.7777777888888888888887777654 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.6  21.3       7.7   1.1e+04     126     226 ..     137     259 ..      88     273 .. 0.50
   2 ?    3.0  18.6     0.035        52     118     236 ..     255     388 ..     246     395 .. 0.69
   3 ?    8.4  19.5   0.00081       1.2     111     243 ..     372     516 ..     369     534 .. 0.70
   4 ?   13.2   5.2   2.9e-05     0.043     126     228 ..     662     760 ..     637     767 .] 0.69

  Alignments for each domain:
  == domain 1  score: -4.6 bits;  conditional E-value: 7.7
     DUF4407 126 qlaaaltaelaeleaqiaalqaeidaaearldalraeaqkeldgtk...................gtgttgvaGkgpaakekkaqldaaqaelaelkak 205
                   ++ +++++ e  ++i+alq++++ + +++++  ++a++ +++ +                   ++  +    + ++ k+ ++ql++ +++ ++lk++
  EEA20390.1 137 AAESRWQEDMHEYIERIDALQSKLKYLAKEAAESARDAASAAKPGSiekqlsekderiallleegQKLSKTELDNRTVIKKLRQQLAESNKQETDLKRR 235
                 222224444444444555555555555555444444444444443333333333333344443332222223444555555666666666666666555 PP

     DUF4407 206 ld......atarlaalraelaeleaer 226
                         +    a++ra++ae+ +++
  EEA20390.1 236 TAklerdvS---DAEARAKRAEASEKK 259
                 334332221...112222222222222 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.035
     DUF4407 118 eeakelkeqlaaa.........ltaelaeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaakekka.qldaaqaelaelkakl 206
                 +++k+++e+l+++          tae ++l++ +++l+++++ a +r++a++  aq+e+   ++ ++t  + +  +ak  ++   +++++e+ +l+++l
  EEA20390.1 255 ASEKKAQESLNSQsraskdlesITAERNALTSTVEELKSQLARAVTRAEAAESRAQAEVVEHSKRRITELEDDLSSAKIERElSEEKLRREIRSLQDNL 353
                 33333334444445555778889999999999999*************************999***************866515567899999999998 PP

     DUF4407 207 d........atarlaalraelaeleaerakeraasqaa 236
                           +a   +l++e++ le+++++ r++ ++ 
  EEA20390.1 354 GrekenahlLEA---ELKSEQSVLESKMESLRSRAEEV 388
                 877764333222...23333333444444444444444 PP

  == domain 3  score: 8.4 bits;  conditional E-value: 0.00081
     DUF4407 111 elaeeqqeeakelkeqlaaa.ltaelaeleaqiaalqaeidaaearldalraeaqkeldgtk....gtgttgvaGkgpaake...........kkaqld 193
                  + e + e+ ++  e++ ++ + +++a+l +qi+ lq++++ a++ ++  +  + + l+g            +a+k++  ++           ++++l+
  EEA20390.1 372 SVLESKMESLRSRAEEVSSStAGETQAKLLRQIETLQTQYAVASENWQGIESSLISRLNGMEkerdE-----IARKEADLRRktrevnirakkAEDELE 465
                 5566666666666666666669999**********************************98744440.....444444444444444444444777777 PP

     DUF4407 194 aaqaelaelkakld.atarlaalraelaeleaerakeraasqaaaaaddGl 243
                 +a++++a+l+++l+  +++l++l+++ ++ e+e+++ r++ ++++++   +
  EEA20390.1 466 TANETIADLDRSLQeTKQQLQKLQQRVEKSEEELNAVRKELADKEKSVESF 516
                 777777777777777666777777777777777777777766666655555 PP

  == domain 4  score: 13.2 bits;  conditional E-value: 2.9e-05
     DUF4407 126 qlaaaltaelaeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaakekkaqldaaqaelaelkakld.atarlaalraelaele 223
                 ql + ++a++++le+++aa + e++   a++d++r+e+ + +   +      ++  + + +e ++q ++++++ ++  + l  +++++++l+a +a+l+
  EEA20390.1 662 QLVERMSATVRRLESERAATKDELERITAQRDEARKEVVELMRE-SE-D---KRKAESRIEELESQVAELDQRYQTTLELLGeKSEQVDELQADIADLK 755
                 44556899*******************************66664.32.2...22333344444444444333333332222248888888888888887 PP

     DUF4407 224 aerak 228
                 + +++
  EEA20390.1 756 KIYRE 760
                 66555 PP

>> GAS  Growth-arrest specific micro-tubule binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   3.2     0.071   1.1e+02      36      83 ..     133     180 ..     126     207 .. 0.75
   2 ?    8.8  15.9   0.00063      0.94      22     119 ..     209     306 ..     204     311 .. 0.91
   3 ?    7.7  21.9    0.0014       2.1      36     162 ..     261     389 ..     256     410 .. 0.88
   4 ?    6.7  20.7    0.0028       4.1      26     127 ..     427     530 ..     409     534 .. 0.82
   5 ?    7.4  13.6    0.0017       2.6      36     134 ..     665     763 ..     662     767 .] 0.81

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.071
         GAS  36 eelkkkeernekelseisqenkrlkepLkkaeeeveeLrkqlknyekd 83 
                 +e ++ e r + +++e+ ++   l+ +Lk + +e +e  ++++   k 
  EEA20390.1 133 AEHQAAESRWQEDMHEYIERIDALQSKLKYLAKEAAESARDAASAAKP 180
                 678888999999999999999999999999999998888777766664 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.00063
         GAS  22 rnNLelIkslKeeieelkkkeernekelseisqenkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkelekelkdlkwehevleqrfekve 119
                  +N ++Ik+l+++++e +k+e+  +++ ++++ + ++ +   k+ae+  ++ ++ l+ +++  ++l+++ a+ + l++ +++lk +      r e++e
  EEA20390.1 209 LDNRTVIKKLRQQLAESNKQETDLKRRTAKLERDVSDAEARAKRAEASEKKAQESLNSQSRASKDLESITAERNALTSTVEELKSQLARAVTRAEAAE 306
                 678899*****************************************************************************998776666666655 PP

  == domain 3  score: 7.7 bits;  conditional E-value: 0.0014
         GAS  36 eelkkkeernekelseisqenkrlkepLkkaeeeveeL..rkqlknyekdkqslknlkarlkelekelkdlkwehevleqrfekvekerdelykkfeaa 132
                 +e  + + r++k+l+ i++e + l+ ++++++ ++++   r+++++ + + +  +++k+r++ele+ l++ k e e  e+++ +  ++ ++   + +++
  EEA20390.1 261 QESLNSQSRASKDLESITAERNALTSTVEELKSQLARAvtRAEAAESRAQAEVVEHSKRRITELEDDLSSAKIERELSEEKLRREIRSLQDNLGREKEN 359
                 5555678899**********************999876226677778888889******************************9999999999999999 PP

         GAS 133 iqevqqktglknllLekklkalqeelEkke 162
                  + +  + + ++ +Le k+++l+ + E+  
  EEA20390.1 360 AHLLEAELKSEQSVLESKMESLRSRAEEVS 389
                 ***********************9999876 PP

  == domain 4  score: 6.7 bits;  conditional E-value: 0.0028
         GAS  26 elIkslKeeieelkkkeernekelseisqenkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkelekelkdlkwehevleqrfe.....kve 119
                 +  + + +e  e+ +ke+  +++  e++ + k+ +++L++a+e ++ L + l++    kq+l++l++r++++e+el++++ e   +e+ +e     k+e
  EEA20390.1 427 SRLNGMEKERDEIARKEADLRRKTREVNIRAKKAEDELETANETIADLDRSLQE---TKQQLQKLQQRVEKSEEELNAVRKELADKEKSVEsfwaqKLE 522
                 555667899999**************************************9986...567999999***********9999988888776422222677 PP

         GAS 120 kerdelyk 127
                 +er ++++
  EEA20390.1 523 EERARWRE 530
                 77766665 PP

  == domain 5  score: 7.4 bits;  conditional E-value: 0.0017
         GAS  36 eelkkkeernekelseisqenkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkelekelkdlkwehevleqrfekvekerdelykkfeaaiq 134
                 e++ +  +r e e ++++ e +r++ +  +a++ev eL ++ ++ +k  +++++l++++ el++ ++++ +    ++++++++++++ +l+k +++ ++
  EEA20390.1 665 ERMSATVRRLESERAATKDELERITAQRDEARKEVVELMRESEDKRKAESRIEELESQVAELDQRYQTTLELLGEKSEQVDELQADIADLKKIYRELVD 763
                 677788888888888888888888888888888888888888888888888888888888888888888888888888888888888888887777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (767 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3333  (0.1859); expected 358.6 (0.02)
Passed bias filter:                      750  (0.0418317); expected 358.6 (0.02)
Passed Vit filter:                       268  (0.0149478); expected 17.9 (0.001)
Passed Fwd filter:                       172  (0.0095934); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 3.13u 0.39s 00:00:03.52 Elapsed: 00:00:00.65
# Mc/sec: 3574.69
//
Query:       EEA20391.1  [L=239]
Description: proteasome regulatory particle subunit (Nas6), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.5e-37  127.3   4.5    5.1e-15   55.8   0.4    3.5  3  Ank_2     Ankyrin repeats (3 copies)
    5.8e-36  122.4   3.8    1.4e-08   35.0   0.1    5.6  6  Ank_4     Ankyrin repeats (many copies)
    1.4e-34  117.6   1.7    1.9e-09   37.6   0.1    4.8  5  Ank_5     Ankyrin repeats (many copies)
    3.3e-29   97.7   1.7      9e-05   22.6   0.0    6.2  6  Ank_3     Ankyrin repeat
    5.1e-23   80.5   4.1      8e-05   22.9   0.0    6.2  6  Ank       Ankyrin repeat


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.7   0.0   1.1e-11   4.1e-08      26      83 .]       7      72 ..       2      72 .. 0.86
   2 !   51.6   0.4     3e-17   1.1e-13       1      81 [.      79     173 ..      79     175 .. 0.82
   3 !   55.8   0.4   1.4e-18   5.1e-15       1      83 []     115     208 ..     115     208 .. 0.89

  Alignments for each domain:
  == domain 1  score: 33.7 bits;  conditional E-value: 1.1e-11
       Ank_2 26 gktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLl.ekgadinlkd 83
                 k+a+h Aa++g++ +v+ Ll++        d+d r p+h+A+ +++l iv+lL+ +k++d++++d
  EEA20391.1  7 AKFAIHEAAREGKTSVVESLLNAnpklasrKDDDERLPIHWAVAYNRLPIVELLVsNKYFDPDVTD 72
                479******************9557787666699*********************55599999887 PP

  == domain 2  score: 51.6 bits;  conditional E-value: 3e-17
       Ank_2   1 LhlAak..ngnle...lvklLl.egadpn.k..ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlek.gadinl 81 
                 L++Aa+  n   e   +++lLl + ad+n k   g++aLh+Aa++ nl +vk+L++h       d+ g+ +Lh Aa  g++ i+k+Ll+  ++ +n+
  EEA20391.1  79 LMIAASlkN--AEgdaIIDLLLrKDADVNiKsvSGQNALHFAASKANLSTVKTLVAHkcsarvKDRRGQLALHRAAAVGSTPILKILLDEgKSPVNA 173
                 899**9542..3233499****99999998469*************9*********99997755599*********99**********772445555 PP

  == domain 3  score: 55.8 bits;  conditional E-value: 1.4e-18
       Ank_2   1 LhlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlekgadinlkd 83 
                 Lh+Aa++ nl++vk L+ +++ ++  +  g+ aLh Aa  g++ i+k+Ll++       +d dg t+Lh+A+++gh +++ lL++ gad++++d
  EEA20391.1 115 LHFAASKANLSTVKTLVaHKCSARvkDrRGQLALHRAAAVGSTPILKILLDEgkspvnaTDVDGLTALHHAISEGHGDAAILLMKAGADLEKRD 208
                 8*****98799******97777777448**********************9667886666699*************9999999988***99887 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.2   0.0     1e-08   3.7e-05       4      55 .]      10      61 ..      10      61 .. 0.97
   2 !   33.8   0.0     1e-11   3.7e-08       2      44 ..      42      84 ..      41      92 .. 0.93
   3 !   21.2   0.0     9e-08   0.00032      17      55 .]      94     131 ..      91     131 .. 0.92
   4 !   32.0   0.1   3.7e-11   1.3e-07       4      55 .]     114     164 ..     113     164 .. 0.93
   5 !   35.0   0.1     4e-12   1.4e-08       4      54 ..     147     197 ..     146     198 .. 0.94
   6 ?    2.3   0.0     0.076   2.7e+02      19      42 ..     196     218 ..     193     218 .. 0.81

  Alignments for each domain:
  == domain 1  score: 24.2 bits;  conditional E-value: 1e-08
       Ank_4  4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55
                a+h aa +g++ +v++Ll+ ++ +  +++++ + ++h A+  +++ i++lL+
  EEA20391.1 10 AIHEAAREGKTSVVESLLNANPKLASRKDDDERLPIHWAVAYNRLPIVELLV 61
                69*********************99*************************96 PP

  == domain 2  score: 33.8 bits;  conditional E-value: 1e-11
       Ank_4  2 ltaLhyaaisgrlelvrlLlekg.adinaqdnrsGetalhiAak 44
                + ++h+a++++rl++v+lL++++  d++ + ++sG+t+l iAa+
  EEA20391.1 42 RLPIHWAVAYNRLPIVELLVSNKyFDPDVT-DGSGWTPLMIAAS 84
                679*****************9988*****9.***********95 PP

  == domain 3  score: 21.2 bits;  conditional E-value: 9e-08
       Ank_4  17 vrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++lLl k+ad+n   + sG++alh+Aa++ n++ +k L+
  EEA20391.1  94 IDLLLRKDADVNIK-SVSGQNALHFAASKANLSTVKTLV 131
                 7899999******9.********************9985 PP

  == domain 4  score: 32.0 bits;  conditional E-value: 3.7e-11
       Ank_4   4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 aLh aa++ +l +v+ L++++ +    ++r+G+ alh+Aa  g+  ilk Ll
  EEA20391.1 114 ALHFAASKANLSTVKTLVAHKCSARV-KDRRGQLALHRAAAVGSTPILKILL 164
                 7********************99655.6*********************997 PP

  == domain 5  score: 35.0 bits;  conditional E-value: 4e-12
       Ank_4   4 aLhyaaisgrlelvrlLlekgad.inaqdnrsGetalhiAakrgnveilklL 54 
                 aLh+aa+ g ++++++Ll+ g++ +na+ + +G+talh+A++ g+ ++++lL
  EEA20391.1 147 ALHRAAAVGSTPILKILLDEGKSpVNAT-DVDGLTALHHAISEGHGDAAILL 197
                 7******************98777***9.******************99998 PP

  == domain 6  score: 2.3 bits;  conditional E-value: 0.076
       Ank_4  19 lLlekgadinaqdnrsGetalhiA 42 
                 lL   gad+ ++ +++G+ a++ A
  EEA20391.1 196 LLMKAGADLEKR-DGEGNLAIDLA 218
                 34477*******.******99876 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.2   0.0    0.0036        13      19      43 ..      10      32 ..       4      39 .. 0.85
   2 !   35.7   0.0     2e-12   7.3e-09       2      56 .]      27      82 ..      26      82 .. 0.88
   3 !   35.1   0.0   3.2e-12   1.2e-08       1      56 []      97     151 ..      96     151 .. 0.94
   4 !   24.2   0.1   8.4e-09     3e-05      13      53 ..     141     182 ..     141     182 .. 0.97
   5 !   37.6   0.1   5.3e-13   1.9e-09       1      56 []     163     218 ..     163     218 .. 0.98

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0036
       Ank_5 19 pLhvAakygaadvvrlLlargadln 43
                ++h Aa+ g  +vv+ Ll  +a+++
  EEA20391.1 10 AIHEAAREGKTSVVESLL--NANPK 32
                7999**************..66655 PP

  == domain 2  score: 35.7 bits;  conditional E-value: 2e-12
       Ank_5  2 lehgpadvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltaldlA 56
                l++ p    r+d +  +p+h+A+ y+++++v+lL+ +   d+++td++G+t+l +A
  EEA20391.1 27 LNANPKLASRKDDDERLPIHWAVAYNRLPIVELLVsNKYFDPDVTDGSGWTPLMIA 82
                6666666677788888************************************9776 PP

  == domain 3  score: 35.1 bits;  conditional E-value: 3.2e-12
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 Ll+++ advn +   g+++Lh+Aa++ +++ v+ L+a+ ++++++d rG++al+ A
  EEA20391.1  97 LLRKD-ADVNIKSVSGQNALHFAASKANLSTVKTLVAHKCSARVKDRRGQLALHRA 151
                 56666.**********************************************9876 PP

  == domain 4  score: 24.2 bits;  conditional E-value: 8.4e-09
       Ank_5  13 dgggntpLhvAakygaadvvrlLl.argadlnltdsrGltal 53 
                 d++g+++Lh Aa  g+ +++++Ll +  +  n+td +Gltal
  EEA20391.1 141 DRRGQLALHRAAAVGSTPILKILLdEGKSPVNATDVDGLTAL 182
                 68899***********************************98 PP

  == domain 5  score: 37.6 bits;  conditional E-value: 5.3e-13
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 Ll++g   vn++d +g t+Lh+A++ g+ d ++lL++ gadl  +d++G++a+dlA
  EEA20391.1 163 LLDEGKSPVNATDVDGLTALHHAISEGHGDAAILLMKAGADLEKRDGEGNLAIDLA 218
                 8999999************************************************9 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.1   0.0    0.0013       4.7       5      23 ..      10      28 ..       9      34 .. 0.87
   2 !   17.2   0.0   1.5e-06    0.0052       3      30 ..      42      69 ..      40      70 .. 0.91
   3 !   22.6   0.0   2.5e-08     9e-05       2      31 .]      75     106 ..      74     106 .. 0.92
   4 !   12.7   0.0   4.1e-05      0.15       2      27 ..     111     135 ..     110     139 .. 0.88
   5 !   14.1   0.0   1.5e-05     0.053       2      30 ..     144     172 ..     143     173 .. 0.89
   6 !   16.8   0.0   1.9e-06    0.0068       1      29 [.     177     204 ..     177     206 .. 0.91

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0013
       Ank_3  5 pLhlAarsgnleivkfLle 23
                ++h+Aar g++++v+ Ll+
  EEA20391.1 10 AIHEAAREGKTSVVESLLN 28
                68****************9 PP

  == domain 2  score: 17.2 bits;  conditional E-value: 1.5e-06
       Ank_3  3 etpLhlAarsgnleivkfLlenkgadvn 30
                + p+h+A+ +++l+iv++L+ nk  d++
  EEA20391.1 42 RLPIHWAVAYNRLPIVELLVSNKYFDPD 69
                789******************9999987 PP

  == domain 3  score: 22.6 bits;  conditional E-value: 2.5e-08
       Ank_3   2 GetpLhlAarsgnle...ivkfLlenkgadvna 31 
                 G+tpL++Aa+  n e   i+++Ll+ k advn+
  EEA20391.1  75 GWTPLMIAASLKNAEgdaIIDLLLR-KDADVNI 106
                 9*************66679******.9****97 PP

  == domain 4  score: 12.7 bits;  conditional E-value: 4.1e-05
       Ank_3   2 GetpLhlAarsgnleivkfLlenkga 27 
                 G+++Lh+Aa+ +nl+ vk L+  + +
  EEA20391.1 111 GQNALHFAASKANLSTVKTLVA-HKC 135
                 99************99*****9.555 PP

  == domain 5  score: 14.1 bits;  conditional E-value: 1.5e-05
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G+ +Lh+Aa  g+++i+k Ll++   +vn
  EEA20391.1 144 GQLALHRAAAVGSTPILKILLDEGKSPVN 172
                 899*******************7777776 PP

  == domain 6  score: 16.8 bits;  conditional E-value: 1.9e-06
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadv 29 
                 +G t+Lh+A++ g+ + +++L +  gad+
  EEA20391.1 177 DGLTALHHAISEGHGDAAILLMK-AGADL 204
                 699*************9999999.8**98 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.6   0.0   0.00076       2.7       5      27 ..      10      31 ..       9      36 .. 0.89
   2 !    6.4   0.0    0.0036        13       5      30 ..      44      71 ..      40      72 .. 0.74
   3 !   22.9   0.0   2.2e-08     8e-05       2      30 ..      75     107 ..      74     109 .. 0.87
   4 !    9.0   0.0   0.00056         2       2      23 ..     111     133 ..     110     141 .. 0.86
   5 !   14.5   0.0     1e-05     0.036       2      31 ..     144     175 ..     143     176 .. 0.82
   6 !   14.7   0.3   8.9e-06     0.032       1      31 [.     177     208 ..     177     208 .. 0.85

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00076
                HHHHHHHHTTHHHHHHHHTTTST CS
         Ank  5 PLHlAatngkkriiklLLhGAnl 27
                + H Aa++gk+++++ LL  An+
  EEA20391.1 10 AIHEAAREGKTSVVESLL-NANP 31
                6799**************.8997 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.0036
                HHHHHHHHTTHHHHHHHH.TT.TSTTCB CS
         Ank  5 PLHlAatngkkriiklLL.hG.Anlnal 30
                P H+A+ ++ + i++lL+ +   +++ +
  EEA20391.1 44 PIHWAVAYNRLPIVELLVsNKyFDPDVT 71
                99****888888****994323566655 PP

  == domain 3  score: 22.9 bits;  conditional E-value: 2.2e-08
                 SBBHHHHHHHHTT...HHHHHHHH.TTTSTTCB CS
         Ank   2 GnTPLHlAatngk...kriiklLL.hGAnlnal 30 
                 G+TPL++Aa+ ++     ii lLL + A++n++
  EEA20391.1  75 GWTPLMIAASLKNaegDAIIDLLLrKDADVNIK 107
                 9********777778899******767****97 PP

  == domain 4  score: 9.0 bits;  conditional E-value: 0.00056
                 SBBHHHHHHHHTTHHHHHHHH.T CS
         Ank   2 GnTPLHlAatngkkriiklLL.h 23 
                 G  +LH Aa+ ++++ +k L+ h
  EEA20391.1 111 GQNALHFAASKANLSTVKTLVaH 133
                 889******9**********986 PP

  == domain 5  score: 14.5 bits;  conditional E-value: 1e-05
                 SBBHHHHHHHHTTHHHHHHHH.TT.TSTTCBT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hG.Anlnald 31 
                 G  +LH+Aa  g++ i+k LL  G + +na+d
  EEA20391.1 144 GQLALHRAAAVGSTPILKILLdEGkSPVNATD 175
                 5669***99889999******7694446**99 PP

  == domain 6  score: 14.7 bits;  conditional E-value: 8.9e-06
                 TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hGAnlnald 31 
                 dG T+LH A+++g+ + + lL   GA+l  +d
  EEA20391.1 177 DGLTALHHAISEGHGDAAILLMkAGADLEKRD 208
                 8*********999977777788779**98776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (239 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      316  (0.0176251); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 1636.15
//
Query:       EEA20392.1  [L=258]
Description: proteasome regulatory particle subunit (Nas6), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-39  134.0   3.9    6.2e-15   55.6   0.4    3.7  4  Ank_2     Ankyrin repeats (3 copies)
    4.3e-32  109.8   1.7    2.2e-09   37.4   0.1    5.6  6  Ank_5     Ankyrin repeats (many copies)
    1.6e-31  108.3   4.2    1.5e-08   35.0   0.0    5.8  6  Ank_4     Ankyrin repeats (many copies)
    6.1e-29   96.9   1.7     0.0001   22.4   0.0    6.2  6  Ank_3     Ankyrin repeat
    1.8e-22   78.7   4.2    8.9e-05   22.8   0.0    6.2  6  Ank       Ankyrin repeat


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.2   0.0   3.3e-11   1.2e-07      26      81 ..       7      70 ..       2      73 .. 0.84
   2 !   19.1   0.0   4.3e-07    0.0015      49      82 ..      90     126 ..      75     127 .. 0.76
   3 !   45.9   0.2   1.8e-15   6.5e-12      11      81 ..     111     192 ..     105     194 .. 0.84
   4 !   55.6   0.4   1.7e-18   6.2e-15       1      83 []     134     227 ..     134     227 .. 0.89

  Alignments for each domain:
  == domain 1  score: 32.2 bits;  conditional E-value: 3.3e-11
       Ank_2 26 gktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLl.ekgadinl 81
                 k+a+h Aa++g++ +v+ Ll++        d+d r p+h+A+ +++l iv+lL+ +k++d+++
  EEA20392.1  7 AKFAIHEAAREGKTSVVESLLNAnpklasrKDDDERLPIHWAVAYNRLPIVELLVsNKYFDPDV 70
                479******************9557787666699*********************555777765 PP

  == domain 2  score: 19.1 bits;  conditional E-value: 4.3e-07
       Ank_2  49 adndgrtpLhyAars....ghleivklLlekgadinlk 82 
                 +d +g+tpL++Aa+     g   i++lLl k+ad+n+k
  EEA20392.1  90 QDGSGWTPLMIAASLknaeG-DAIIDLLLRKDADVNIK 126
                 5678*********8865544.499*****99*****98 PP

  == domain 3  score: 45.9 bits;  conditional E-value: 1.8e-15
       Ank_2  11 elvklLl.egadpn.k..ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlek.gadinl 81 
                  +++lLl + ad+n k   g++aLh+Aa++ nl +vk+L++h       d+ g+ +Lh Aa  g++ i+k+Ll+  ++ +n+
  EEA20392.1 111 AIIDLLLrKDADVNiKsvSGQNALHFAASKANLSTVKTLVAHkcsarvKDRRGQLALHRAAAVGSTPILKILLDEgKSPVNA 192
                 49999**99999998469*************9*********99997755599*********99**********772445555 PP

  == domain 4  score: 55.6 bits;  conditional E-value: 1.7e-18
       Ank_2   1 LhlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlekgadinlkd 83 
                 Lh+Aa++ nl++vk L+ +++ ++  +  g+ aLh Aa  g++ i+k+Ll++       +d dg t+Lh+A+++gh +++ lL++ gad++++d
  EEA20392.1 134 LHFAASKANLSTVKTLVaHKCSARvkDrRGQLALHRAAAVGSTPILKILLDEgkspvnaTDVDGLTALHHAISEGHGDAAILLMKAGADLEKRD 227
                 8*****98799******97777777448**********************9667886666699*************9999999988***99887 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.9   0.0    0.0046        17      19      43 ..      10      32 ..       4      36 .. 0.85
   2 !   18.5   0.0   5.1e-07    0.0018      13      45 ..      38      71 ..      33      76 .. 0.84
   3 !    7.0   0.0    0.0021       7.6      12      29 ..      90     107 ..      87     109 .. 0.75
   4 !   34.9   0.0   3.7e-12   1.3e-08       1      56 []     116     170 ..     115     170 .. 0.94
   5 !   29.4   0.1     2e-10   7.1e-07       1      53 [.     149     201 ..     149     201 .. 0.94
   6 !   37.4   0.1   6.1e-13   2.2e-09       1      56 []     182     237 ..     182     237 .. 0.98

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0046
       Ank_5 19 pLhvAakygaadvvrlLlargadln 43
                ++h Aa+ g  +vv+ Ll  +a+++
  EEA20392.1 10 AIHEAAREGKTSVVESLL--NANPK 32
                7999**************..66655 PP

  == domain 2  score: 18.5 bits;  conditional E-value: 5.1e-07
       Ank_5 13 dgggntpLhvAakygaadvvrlLl.argadlnlt 45
                d +  +p+h+A+ y+++++v+lL+ +   d+++t
  EEA20392.1 38 DDDERLPIHWAVAYNRLPIVELLVsNKYFDPDVT 71
                445559******************9998888876 PP

  == domain 3  score: 7.0 bits;  conditional E-value: 0.0021
       Ank_5  12 ldgggntpLhvAakygaa 29 
                 +dg g tpL++Aa+  +a
  EEA20392.1  90 QDGSGWTPLMIAASLKNA 107
                 567777*******95544 PP

  == domain 4  score: 34.9 bits;  conditional E-value: 3.7e-12
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 Ll+++ advn +   g+++Lh+Aa++ +++ v+ L+a+ ++++++d rG++al+ A
  EEA20392.1 116 LLRKD-ADVNIKSVSGQNALHFAASKANLSTVKTLVAHKCSARVKDRRGQLALHRA 170
                 56666.**********************************************9876 PP

  == domain 5  score: 29.4 bits;  conditional E-value: 2e-10
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltal 53 
                 L++h  ++   +d++g+++Lh Aa  g+ +++++Ll +  +  n+td +Gltal
  EEA20392.1 149 LVAHK-CSARVKDRRGQLALHRAAAVGSTPILKILLdEGKSPVNATDVDGLTAL 201
                 78888.88888999999***********************************98 PP

  == domain 6  score: 37.4 bits;  conditional E-value: 6.1e-13
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 Ll++g   vn++d +g t+Lh+A++ g+ d ++lL++ gadl  +d++G++a+dlA
  EEA20392.1 182 LLDEGKSPVNATDVDGLTALHHAISEGHGDAAILLMKAGADLEKRDGEGNLAIDLA 237
                 8999999************************************************9 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.0   0.0   1.2e-08   4.2e-05       4      55 .]      10      61 ..      10      61 .. 0.97
   2 !   21.7   0.0   6.4e-08   0.00023       2      44 ..      42     103 ..      41     109 .. 0.87
   3 !   21.0   0.0     1e-07   0.00036      17      55 .]     113     150 ..     110     150 .. 0.92
   4 !   31.2   0.1   6.3e-11   2.3e-07       4      55 .]     133     183 ..     133     183 .. 0.94
   5 !   35.0   0.0   4.2e-12   1.5e-08       4      54 ..     166     216 ..     164     217 .. 0.94
   6 ?    2.1   0.0     0.084     3e+02      19      42 ..     215     237 ..     212     237 .. 0.81

  Alignments for each domain:
  == domain 1  score: 24.0 bits;  conditional E-value: 1.2e-08
       Ank_4  4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55
                a+h aa +g++ +v++Ll+ ++ +  +++++ + ++h A+  +++ i++lL+
  EEA20392.1 10 AIHEAAREGKTSVVESLLNANPKLASRKDDDERLPIHWAVAYNRLPIVELLV 61
                69*********************99*************************96 PP

  == domain 2  score: 21.7 bits;  conditional E-value: 6.4e-08
       Ank_4   2 ltaLhyaaisgrlelvrlLlekg.ad...................inaqdnrsGetalhiAak 44 
                 + ++h+a++++rl++v+lL++++  d                      q ++sG+t+l iAa+
  EEA20392.1  42 RLPIHWAVAYNRLPIVELLVSNKyFDpdvtvrlpllitfigaffsFFLQ-DGSGWTPLMIAAS 103
                 679*****************87654456999999999998888888888.***********95 PP

  == domain 3  score: 21.0 bits;  conditional E-value: 1e-07
       Ank_4  17 vrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++lLl k+ad+n   + sG++alh+Aa++ n++ +k L+
  EEA20392.1 113 IDLLLRKDADVNIK-SVSGQNALHFAASKANLSTVKTLV 150
                 7899999******9.********************9985 PP

  == domain 4  score: 31.2 bits;  conditional E-value: 6.3e-11
       Ank_4   4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 aLh aa++ +l +v+ L++++ +    ++r+G+ alh+Aa  g+  ilk Ll
  EEA20392.1 133 ALHFAASKANLSTVKTLVAHKCSARV-KDRRGQLALHRAAAVGSTPILKILL 183
                 69*******************99655.6*********************997 PP

  == domain 5  score: 35.0 bits;  conditional E-value: 4.2e-12
       Ank_4   4 aLhyaaisgrlelvrlLlekgad.inaqdnrsGetalhiAakrgnveilklL 54 
                 aLh+aa+ g ++++++Ll+ g++ +na+ + +G+talh+A++ g+ ++++lL
  EEA20392.1 166 ALHRAAAVGSTPILKILLDEGKSpVNAT-DVDGLTALHHAISEGHGDAAILL 216
                 7******************98777***9.******************99998 PP

  == domain 6  score: 2.1 bits;  conditional E-value: 0.084
       Ank_4  19 lLlekgadinaqdnrsGetalhiA 42 
                 lL   gad+ ++ +++G+ a++ A
  EEA20392.1 215 LLMKAGADLEKR-DGEGNLAIDLA 237
                 34477*******.******99876 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   0.0    0.0015       5.2       5      23 ..      10      28 ..       9      34 .. 0.87
   2 !   17.0   0.0   1.6e-06    0.0058       3      30 ..      42      69 ..      40      70 .. 0.91
   3 !   22.4   0.0   2.8e-08    0.0001       2      31 .]      94     125 ..      93     125 .. 0.92
   4 !   12.6   0.0   4.6e-05      0.17       2      27 ..     130     154 ..     129     158 .. 0.88
   5 !   13.9   0.0   1.7e-05      0.06       2      30 ..     163     191 ..     162     192 .. 0.89
   6 !   16.7   0.0   2.1e-06    0.0076       1      29 [.     196     223 ..     196     225 .. 0.91

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0015
       Ank_3  5 pLhlAarsgnleivkfLle 23
                ++h+Aar g++++v+ Ll+
  EEA20392.1 10 AIHEAAREGKTSVVESLLN 28
                68****************9 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 1.6e-06
       Ank_3  3 etpLhlAarsgnleivkfLlenkgadvn 30
                + p+h+A+ +++l+iv++L+ nk  d++
  EEA20392.1 42 RLPIHWAVAYNRLPIVELLVSNKYFDPD 69
                789******************9999987 PP

  == domain 3  score: 22.4 bits;  conditional E-value: 2.8e-08
       Ank_3   2 GetpLhlAarsgnle...ivkfLlenkgadvna 31 
                 G+tpL++Aa+  n e   i+++Ll+ k advn+
  EEA20392.1  94 GWTPLMIAASLKNAEgdaIIDLLLR-KDADVNI 125
                 9*************66679******.9****97 PP

  == domain 4  score: 12.6 bits;  conditional E-value: 4.6e-05
       Ank_3   2 GetpLhlAarsgnleivkfLlenkga 27 
                 G+++Lh+Aa+ +nl+ vk L+  + +
  EEA20392.1 130 GQNALHFAASKANLSTVKTLVA-HKC 154
                 99************99*****9.555 PP

  == domain 5  score: 13.9 bits;  conditional E-value: 1.7e-05
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G+ +Lh+Aa  g+++i+k Ll++   +vn
  EEA20392.1 163 GQLALHRAAAVGSTPILKILLDEGKSPVN 191
                 899*******************7777766 PP

  == domain 6  score: 16.7 bits;  conditional E-value: 2.1e-06
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadv 29 
                 +G t+Lh+A++ g+ + +++L +  gad+
  EEA20392.1 196 DGLTALHHAISEGHGDAAILLMK-AGADL 223
                 699*************9999999.8**98 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.4   0.0   0.00084         3       5      27 ..      10      31 ..       9      36 .. 0.89
   2 !    5.4   0.0    0.0076        27       5      22 ..      44      61 ..      40      71 .. 0.79
   3 !   22.8   0.0   2.5e-08   8.9e-05       2      30 ..      94     126 ..      93     128 .. 0.87
   4 !    8.8   0.0   0.00063       2.2       2      23 ..     130     152 ..     129     160 .. 0.86
   5 !   14.4   0.0   1.1e-05      0.04       2      31 ..     163     194 ..     162     195 .. 0.82
   6 !   14.5   0.3   9.9e-06     0.036       1      31 [.     196     227 ..     196     227 .. 0.85

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00084
                HHHHHHHHTTHHHHHHHHTTTST CS
         Ank  5 PLHlAatngkkriiklLLhGAnl 27
                + H Aa++gk+++++ LL  An+
  EEA20392.1 10 AIHEAAREGKTSVVESLL-NANP 31
                6799**************.8997 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.0076
                HHHHHHHHTTHHHHHHHH CS
         Ank  5 PLHlAatngkkriiklLL 22
                P H+A+ ++ + i++lL+
  EEA20392.1 44 PIHWAVAYNRLPIVELLV 61
                99****888888***999 PP

  == domain 3  score: 22.8 bits;  conditional E-value: 2.5e-08
                 SBBHHHHHHHHTT...HHHHHHHH.TTTSTTCB CS
         Ank   2 GnTPLHlAatngk...kriiklLL.hGAnlnal 30 
                 G+TPL++Aa+ ++     ii lLL + A++n++
  EEA20392.1  94 GWTPLMIAASLKNaegDAIIDLLLrKDADVNIK 126
                 9********777778899******767****97 PP

  == domain 4  score: 8.8 bits;  conditional E-value: 0.00063
                 SBBHHHHHHHHTTHHHHHHHH.T CS
         Ank   2 GnTPLHlAatngkkriiklLL.h 23 
                 G  +LH Aa+ ++++ +k L+ h
  EEA20392.1 130 GQNALHFAASKANLSTVKTLVaH 152
                 889******9**********986 PP

  == domain 5  score: 14.4 bits;  conditional E-value: 1.1e-05
                 SBBHHHHHHHHTTHHHHHHHH.TT.TSTTCBT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hG.Anlnald 31 
                 G  +LH+Aa  g++ i+k LL  G + +na+d
  EEA20392.1 163 GQLALHRAAAVGSTPILKILLdEGkSPVNATD 194
                 5669***99889999******7694446**99 PP

  == domain 6  score: 14.5 bits;  conditional E-value: 9.9e-06
                 TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hGAnlnald 31 
                 dG T+LH A+++g+ + + lL   GA+l  +d
  EEA20392.1 196 DGLTALHHAISEGHGDAAILLMkAGADLEKRD 227
                 8*********999977777788779**98776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (258 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       438  (0.0244297); expected 358.6 (0.02)
Passed bias filter:                      396  (0.0220871); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.41
# Mc/sec: 1881.71
//
Query:       EEA20393.1  [L=447]
Description: mRNA splicing protein (Prp5), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.4e-44  148.4  12.9    5.8e-09   36.5   0.1    7.3  7  WD40         WD domain, G-beta repeat
    1.9e-06   28.1   0.8        3.2    8.1   0.0    5.3  6  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
     0.0065   15.8   0.0      0.014   14.8   0.0    1.6  1  WD40_like    WD40-like domain
  ------ inclusion threshold ------
      0.079   11.6   1.7         39    2.7   0.0    4.1  5  Nup160       Nucleoporin Nup120/160


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.5   0.1   1.3e-12   5.8e-09       1      38 []     128     166 ..     128     166 .. 0.94
   2 !   28.6   0.0     4e-10   1.8e-06       4      38 .]     173     208 ..     170     208 .. 0.93
   3 !   32.7   0.3     2e-11     9e-08       2      38 .]     213     250 ..     212     250 .. 0.96
   4 !   23.5   0.1   1.6e-08   7.1e-05       2      38 .]     255     292 ..     254     292 .. 0.80
   5 !    7.3   0.0     0.002       9.1       1      38 []     296     333 ..     296     333 .. 0.90
   6 !   13.2   0.0   2.8e-05      0.12       4      38 .]     340     374 ..     337     374 .. 0.88
   7 !    9.5   0.0   0.00041       1.8      18      38 .]     404     424 ..     377     424 .. 0.73

  Alignments for each domain:
  == domain 1  score: 36.5 bits;  conditional E-value: 1.3e-12
                 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 ++++r+++GH ++v++la+ p++ w+asG  D+t++iW+
  EEA20393.1 128 WKLMRVISGHlGWVRALAVEPNNEWFASGAGDRTIKIWN 166
                 67899************************56*******8 PP

  == domain 2  score: 28.6 bits;  conditional E-value: 4e-10
                 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                   tltGH s v++la+sp +++l+s+++D+ v+ Wd
  EEA20393.1 173 RLTLTGHiSTVRGLAVSPRHPYLFSCGEDKMVKCWD 208
                 5689*******************************9 PP

  == domain 3  score: 32.7 bits;  conditional E-value: 2e-11
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 + +r++ GH s+v+sla +p+ + l++G++Dg  r+Wd
  EEA20393.1 213 KVIRHYHGHlSGVYSLAIHPNLDVLVTGGRDGVARVWD 250
                 5689*********************************9 PP

  == domain 4  score: 23.5 bits;  conditional E-value: 1.6e-08
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +++++l+GH + v +++ +   + +++Gs D t+r+Wd
  EEA20393.1 255 SNIHVLSGHkGTVADVKCQEADPQIITGSLDTTIRLWD 292
                 689******555777776666666779**********9 PP

  == domain 5  score: 7.3 bits;  conditional E-value: 0.002
                 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 g+++++lt H ++v+ la +p    +as+s   +++ W+
  EEA20393.1 296 GKTMGVLTHHkKGVRNLAIHPKEFTFASAS-TASIKQWK 333
                 578899**9*999*********99999999.99999995 PP

  == domain 6  score: 13.2 bits;  conditional E-value: 2.8e-05
                 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   4 lrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 
                 ++ ++G++  ++s+a++ d+ ++ sG+d+g+  +Wd
  EEA20393.1 340 MQNFEGQNAvINSIAVNEDNVLF-SGGDNGSMSFWD 374
                 67799998856***********7.7**********9 PP

  == domain 7  score: 9.5 bits;  conditional E-value: 0.00041
                 EETTSSEEEEEETTSEEEEEE CS
        WD40  18 fspdgawlasGsdDgtvriWd 38 
                 f++ g  l+ G  D+t++iW+
  EEA20393.1 404 FDRTGLRLIVGEADKTIKIWK 424
                 7777777888*77*******6 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.1   0.0   0.00071       3.2      23      76 ..     121     176 ..     109     184 .. 0.83
   2 ?    3.3   0.0     0.022        99      39      78 ..     181     220 ..     175     229 .. 0.89
   3 !    7.7   0.1   0.00095       4.3      19      84 ..     204     267 ..     199     274 .. 0.81
   4 !    5.6   0.1    0.0042        19      28      84 ..     247     309 ..     242     334 .. 0.83
   5 ?    1.6   0.0     0.075   3.4e+02      41      80 ..     350     388 ..     332     394 .. 0.81
   6 ?   -0.9   0.0      0.48   2.1e+03      45      67 ..     403     425 ..     393     437 .. 0.77

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00071
  ANAPC4_WD40  23 Rlngqrvwtl..eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhsl 76 
                  R +++  w+l    +++ + vr+La +p+++ +a +  d ++++ +  +g +  +l
   EEA20393.1 121 RPDWHAPWKLmrVISGHLGWVRALAVEPNNEWFASGAGDRTIKIWNLATGSLRLTL 176
                  77777777775544566778***************************999887665 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.022
  ANAPC4_WD40  39 sevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsv 78 
                  s+vr+La +p    L    +d  v+  d e  kv+++++ 
   EEA20393.1 181 STVRGLAVSPRHPYLFSCGEDKMVKCWDLEANKVIRHYHG 220
                  789********************************99865 PP

  == domain 3  score: 7.7 bits;  conditional E-value: 0.00095
  ANAPC4_WD40  19 llvfRlngqrvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekav 84 
                  + +  l+ ++v     +++ s v sLa +p+  +L+ +  dg  r+ d+ +   +h ls ++ + v
   EEA20393.1 204 VKCWDLEANKVIRH-YHGHLSGVYSLAIHPNLDVLVTGGRDGVARVWDMRTRSNIHVLSGHKGT-V 267
                  55555666666666.57778899*********************************99988774.4 PP

  == domain 4  score: 5.6 bits;  conditional E-value: 0.0042
  ANAPC4_WD40  28 rvwtl.......eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekav 84 
                  rvw++         ++++++v +++ ++ +  +  +  d+++rl d   gk++  l+ +++  v
   EEA20393.1 247 RVWDMrtrsnihVLSGHKGTVADVKCQEADPQIITGSLDTTIRLWDLAAGKTMGVLTHHKKG-V 309
                  566666655555446789999*******************************9999888774.4 PP

  == domain 5  score: 1.6 bits;  conditional E-value: 0.075
  ANAPC4_WD40  41 vrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvks 80 
                  ++s+a + ++++L  + ++g++++ d ++g+  +sl++++
   EEA20393.1 350 INSIAVN-EDNVLFSGGDNGSMSFWDWKTGHRFQSLDTTA 388
                  5555554.568999****************9999988765 PP

  == domain 6  score: -0.9 bits;  conditional E-value: 0.48
  ANAPC4_WD40  45 aWkpdgklLavaysdgevrllda 67 
                   +   g  L v+ +d ++++ + 
   EEA20393.1 403 TFDRTGLRLIVGEADKTIKIWKP 425
                  56778889999999999999765 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0     3e-06     0.014       2      74 ..     224     297 ..     223     372 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 3e-06
   WD40_like   2 eiYsidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvkllddd.lilvvtlDGtillsllenee 74 
                  +Ys+ i ++ ++++ Gg+d  ++v ++++   + ++ + +  v  vk  + d +i+ ++lD ti l +l  ++
  EEA20393.1 224 GVYSLAIHPNLDVLVTGGRDGVARVWDMRTRSNIHVLSGHKGTVADVKCQEADpQIITGSLDTTIRLWDLAAGK 297
                 59***********************************************999989**********999888776 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.1     0.023     1e+02     239     252 ..     159     172 ..     157     184 .. 0.86
   2 ?    0.5   0.0      0.04   1.8e+02     231     255 ..     193     217 ..     179     227 .. 0.86
   3 ?    2.7   0.0    0.0086        39     231     254 ..     235     258 ..     220     278 .. 0.81
   4 ?    2.2   0.0     0.012        54     233     255 ..     279     301 ..     263     380 .. 0.78
   5 ?   -1.6   0.0      0.17   7.8e+02     221     259 ..     349     387 ..     337     431 .. 0.75

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.023
                 T-EEEEEETTTTEE CS
      Nup160 239 dgkLrvWnlltgkc 252
                 d+++++Wnl+tg++
  EEA20393.1 159 DRTIKIWNLATGSL 172
                 89*********986 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.04
                 TEEEEEETT-EEEEEETTTTEEEEE CS
      Nup160 231 tylfalsrdgkLrvWnlltgkclat 255
                  ylf+   d+ ++ W+l+ +k++++
  EEA20393.1 193 PYLFSCGEDKMVKCWDLEANKVIRH 217
                 58999999************99876 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.0086
                 TEEEEEETT-EEEEEETTTTEEEE CS
      Nup160 231 tylfalsrdgkLrvWnlltgkcla 254
                 ++l++  rdg+ rvW+ +t + + 
  EEA20393.1 235 DVLVTGGRDGVARVWDMRTRSNIH 258
                 6788888************88765 PP

  == domain 4  score: 2.2 bits;  conditional E-value: 0.012
                 EEEEETT-EEEEEETTTTEEEEE CS
      Nup160 233 lfalsrdgkLrvWnlltgkclat 255
                 + + s+d ++r+W+l+ gk++ +
  EEA20393.1 279 IITGSLDTTIRLWDLAAGKTMGV 301
                 667799*********99988765 PP

  == domain 5  score: -1.6 bits;  conditional E-value: 0.17
                 EET......TTTEEEEEETT-EEEEEETTTTEEEEEEE-- CS
      Nup160 221 vavavvei.gqtylfalsrdgkLrvWnlltgkclatidll 259
                 v+++++ + ++++lf+   +g +  W+ +tg +  + d++
  EEA20393.1 349 VINSIA-VnEDNVLFSGGDNGSMSFWDWKTGHRFQSLDTT 387
                 444443.238999999999999999999999999888877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (447 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       394  (0.0219756); expected 358.6 (0.02)
Passed bias filter:                      334  (0.018629); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.40
# Mc/sec: 3376.73
//
Query:       EEA20394.1  [L=417]
Description: FMN binding oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.5e-43  148.7   0.0    3.3e-43  148.3   0.0    1.1  1  Oxidored_FMN  NADH:flavin oxidoreductase / NADH oxidase famil
     0.0032   16.6   0.3     0.0064   15.6   0.0    1.6  2  Dus           Dihydrouridine synthase (Dus)


Domain annotation for each model (and alignments):
>> Oxidored_FMN  NADH:flavin oxidoreductase / NADH oxidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  148.3   0.0   3.7e-47   3.3e-43       4     335 ..       7     360 ..       4     365 .. 0.81

  Alignments for each domain:
  == domain 1  score: 148.3 bits;  conditional E-value: 3.7e-47
                   S-EEETT.EEESSSEEE----S-TTTTTCS.HHHHHHHHHHHHHHTT-SEEEEEEEESSCCC-SCTTSEE-..S.SGGGHHHHHHHHHHHHHTT-EE CS
  Oxidored_FMN   4 kPikign.mtLknRivmapmtrlraldkgnvledlaaeyysqraeipvtliiteaafvnpksggfdnapgi..w.deeqieewrklteavhengskv 96 
                   +P+k++   +LknR+v a+m    + ++g ++++l  + y++  e++++++ t+ + v+ +  g + +  +    + e + +w++ +   + n+  +
    EEA20394.1   7 QPLKLKCgLELKNRLVKASMAENMSDPNG-MPTELHNKVYTEWGEGGWGMVLTGNVQVDRNYLGDPRDVTLdlSrKPELLSKWKTWASTCRSNDTPI 102
                   8*****999*****************999.888899999999****************99977777766652232457799**************** PP

                   EEEEE--GGGS..SCSTCEC..SS.ESSSSSTTT-.......S...CS..-EE--HHHHHHHHHHHHHHHHHHHHTT-SEEEEEE-CTSHHHHHH-T CS
  Oxidored_FMN  97 vvqlwhlGreakseyladqevdspsdpvaldaqee......esaeevy..kkeltkeeikqliqefveAAkraieAgfDgVeihganGYLlnqFlsp 185
                   ++q+ h Gr++++   a++      +p+al+ ++        +   v+  ++e+++ +i  +i++fve+ ++a eAgf gV++h+a+GYLl qFls 
    EEA20394.1 103 IMQINHPGRQSPAGAGARPFLAKNLAPSALPLNMGpgllakFASAFVFgtPREMNQTDIDLVIHQFVECSQLAAEAGFHGVQVHAAHGYLLTQFLSA 199
                   ************8887777744555556666665566667644445556689********************************************* PP

                   TT----STTSSSHHHHHHHHHHHHHHHHHHH-SSS.EEEEEECE--STTS--HHHH.HHHHHHHCHCCEEEEEEETT-SSSSS.......TTS-TTT CS
  Oxidored_FMN 186 ksnkrtDeygGslenRarFllevvdaVkeavgeer.vgyRlSpedvvekgldfaet.aqkivllkelekrlkdgkklalvhaa.......eprkrga 273
                   ++n+rtDeyg s e+Ra+ +++++ aV+ a  e + vg++l   d   ++    e  + ++++++e ++++ +++ +++ ++        + ++ ++
    EEA20394.1 200 ETNHRTDEYGCSPEKRAKVVIDIIHAVRAATPEGFcVGVKLNSVDHQSPE--ALEGcISQLKMIHEAGVDFVEISGGSYEDVTfitggtsQSQQEKS 294
                   ******************************88777999999777765554..45555789************9998888665411111112233333 PP

                   THHHCCTTHHH.......HHHC.CCHSSEEEE-SS--SHHHHHHHHHTTS-SEEEESTHHHH-TTHHHHH CS
  Oxidored_FMN 274 gsvrteqeknt.......efvk.evwkkplitvgriadeekaaeivaegeadLvamgRefladpdlvekl 335
                    +++ +            + ++ +v + pl+ +g++     +  ++++   d+++++R+ +  p l++ +
    EEA20394.1 295 AHTVAR----EafflefaDAIRsQVPEIPLLLTGGFRTRRGMVAAMQNSSCDMIGLARPAVLTPSLPKSI 360
                   344444....033444555565145689*************************************99865 PP

>> Dus  Dihydrouridine synthase (Dus)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.3      0.55     5e+03     138     159 ..     166     187 ..     160     188 .. 0.79
   2 !   15.6   0.0   7.1e-07    0.0064      98     238 ..     207     371 ..     200     380 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 0.55
                 C.HHHHHHHHHHCT-SEEEEES CS
         Dus 138 enalelakiveaaGaqaltvHg 159
                 ++ +e  + + +aG   + vH+
  EEA20394.1 166 HQFVECSQLAAEAGFHGVQVHA 187
                 4578888888999999999997 PP

  == domain 2  score: 15.6 bits;  conditional E-value: 7.1e-07
                 EEGGGGGGSHHHHHHHHHHHHCCSS..S-EEEEEESESS...TTTC.HHHHHHHHHHCT-SEEEEESS...................ECCCTT-CG--C CS
         Dus  98 gaGaaLlrkpdlvaqivkavvkave..iPvtvkirigid...deeenalelakiveaaGaqaltvHgR...................traqnyegtadw 172
                 ++G++  + +++v +i++av+ a++  + v vk     +   ++ e ++   k++ +aG++++ + g                    ++ +  ++   +
  EEA20394.1 207 EYGCSPEKRAKVVIDIIHAVRAATPegFCVGVKLNSVDHqspEALEGCISQLKMIHEAGVDFVEISGGsyedvtfitggtsqsqqekSAHTVAREAFFL 305
                 577777788999************9888899999888888888889999999***************************77644433333333334456 PP

                 HHHHHHHHH-S.S-EEEESS--SHHHHHHHHHHH--SEEEESCHHCCSTTHHHHHHHHHHSC----- CS
         Dus 173 eaIkevkqavs.ipviaNGdIkdaedaqaileetGadgvmigrgalgnPwlfaestavktgeaepap 238
                 e   +++ +v+ ip++  G+ ++++ + a+++++ +d +  +r a   P l ++   ++t+ ++++ 
  EEA20394.1 306 EFADAIRSQVPeIPLLLTGGFRTRRGMVAAMQNSSCDMIGLARPAVLTPSLPKS-IVLDTKVPDEEA 371
                 77899*********************************************9984.356666665555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (417 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       359  (0.0200234); expected 358.6 (0.02)
Passed bias filter:                      350  (0.0195214); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.30s 00:00:00.82 Elapsed: 00:00:00.48
# Mc/sec: 2638.88
//
Query:       EEA20395.1  [L=805]
Description: origin recognition complex subunit Orc1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.6e-15   56.6   0.0    6.9e-15   55.6   0.0    1.5  1  AAA           ATPase family associated with various cellular 
    5.1e-13   49.0   1.6    6.3e-12   45.5   0.7    2.5  2  AAA_lid_10    AAA lid domain
    2.2e-10   41.2   0.0    1.8e-09   38.2   0.0    2.4  1  AAA_16        AAA ATPase domain
    1.6e-08   34.9   0.0    4.6e-08   33.4   0.0    1.8  1  AAA_22        AAA domain
    4.8e-06   26.4   0.0    1.5e-05   24.8   0.0    1.8  1  BAH           BAH domain
     0.0019   18.5   0.0     0.0042   17.4   0.0    1.5  1  AAA_19        AAA domain
     0.0042   16.9   0.2      0.011   15.5   0.0    1.8  2  AAA_11        AAA domain
     0.0089   16.3   0.0      0.023   15.0   0.0    1.7  1  AAA_28        AAA domain
  ------ inclusion threshold ------
       0.02   14.8   0.0      0.064   13.2   0.0    1.9  1  NACHT         NACHT domain
      0.046   12.9   0.0      0.072   12.2   0.0    1.2  1  PIF1          PIF1-like helicase
       0.05   14.0   0.0       0.25   11.8   0.0    2.2  1  RNA_helicase  RNA helicase
      0.052   14.1   0.0       0.16   12.5   0.0    1.9  1  AAA_18        AAA domain
      0.087   12.7   0.0        1.8    8.4   0.0    2.5  2  ATPase_2      ATPase domain predominantly from Archaea
        0.1   12.7   0.0       0.53   10.4   0.0    2.2  2  AAA_33        AAA domain
       0.13   11.5   0.0       0.33   10.1   0.0    1.6  2  KAP_NTPase    KAP family P-loop domain
       0.15   12.0   0.0       0.41   10.7   0.0    1.7  1  TsaE          Threonylcarbamoyl adenosine biosynthesis protei
       0.18   11.6   0.0         19    5.1   0.0    3.1  3  MEDS          MEDS: MEthanogen/methylotroph, DcmR Sensory dom


Domain annotation for each model (and alignments):
>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.6   0.0   6.6e-18   6.9e-15       1     129 [.     382     524 ..     382     527 .. 0.81

  Alignments for each domain:
  == domain 1  score: 55.6 bits;  conditional E-value: 6.6e-18
                 EEEESSTTSSHHHHHHHHHHHHTHE..........EEEEETTTCSSS............STTHHHHHHHHHHHHHHHTS....TSEEEEEETGGGHHHH CS
         AAA   1 vllyGppGtGKTllakavakelgve..........fleisgsellsk............yvgesekkirelfkeakeka....kpsilfiDEidalaks 73 
                 ++++G+pGtGKT++++ v+ +l+            f+ei+g+++++                 s+++  +l+++  +       p+++++DE+d+l+++
  EEA20395.1 382 IYISGTPGTGKTATVREVIAQLNNAvldeemddfiFVEINGMKVTDPhqsysllwealkGDRVSPSHALDLLEREFSYPsprrVPCVVLMDELDQLVTK 480
                 5899*****************96333444455555**********6689****99998855555566666665532222466688************** PP

                 HTTCCCHHHHHHHHHHHHHHHHTTTSSSTEEEEEEESSGGGSTHHHHSTTSSEEEE CS
         AAA  74 rsgseseeeervvnqLlteldgvkkkeskvivigatnrpdkldpallrgRfdrkie 129
                 +           ++++++++++   ++s++iv++++n++d +++ l  +++++++ 
  EEA20395.1 481 N-----------QSVMYNFFNWPALRHSRLIVLAVANTMDLPERTLS-NKISSRLG 524
                 *...........*********************************99.88887765 PP

>> AAA_lid_10  AAA lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.0      0.38     4e+02      47      63 ..     536     552 ..     533     555 .. 0.89
   2 !   45.5   0.7     6e-15   6.3e-12      46      82 ..     555     591 ..     553     605 .. 0.88

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.38
                 ----HHHHHHHHHHT-T CS
  AAA_lid_10  47 ddaieiasrkvAsvsgd 63 
                  d iei+s ++A+v g+
  EEA20395.1 536 TDLIEIISSRLANVPGN 552
                 589***********987 PP

  == domain 2  score: 45.5 bits;  conditional E-value: 6e-15
                 -----HHHHHHHHHHT-TTTTHHHHHHHHHHHHHHHT CS
  AAA_lid_10  46 sddaieiasrkvAsvsgdarrAlkiCkrAvEiaekdy 82 
                   dai+ asrkvA vsgdarrAl iC+rAvEiae++ 
  EEA20395.1 555 DPDAIQFASRKVAAVSGDARRALDICRRAVEIAEQEC 591
                 579*******************************974 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.2   0.0   1.7e-12   1.8e-09       2     164 ..     356     494 ..     355     502 .. 0.81

  Alignments for each domain:
  == domain 1  score: 38.2 bits;  conditional E-value: 1.7e-12
      AAA_16   2 lvGReeeleqLlsale.rvrsgrpelvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipysalaqalareellrqlldeaesaeleawre 99 
                 l++R +e e++ + l+ ++++g++ ++++sG +G+GK++ vre+  +l+ +   +l ++ d++            + + e+     +++ ++    w +
  EEA20395.1 356 LPCRNAEFETVYTHLSaAIAEGSGTCIYISGTPGTGKTATVREVIAQLNNA---VLDEEMDDF------------I-FVEINGMKVTDPHQSYSLLWEA 438
                 89*********8888868888888*************************99...899999999............3.3355555666655567777777 PP

      AAA_16 100 kleealaavpelagaeasrllellkrllallsrderplvlvlDdlqwadeaslqllaaLlrlles 164
                    ++++         +s+ l+ll r +++ s+++ p v+++D+l+++ +  ++++++++  +  
  EEA20395.1 439 LKGDRVS---------PSHALDLLEREFSYPSPRRVPCVVLMDELDQLVTKNQSVMYNFFNWPAL 494
                 6666666.........4899999999999999999999999999999999999999988876666 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.4   0.0   4.3e-11   4.6e-08       4     112 ..     378     489 ..     375     512 .. 0.79

  Alignments for each domain:
  == domain 1  score: 33.4 bits;  conditional E-value: 4.3e-11
      AAA_22   4 tagilvvtGesGtGKTtllrrlleqldeeakaee.erpevvfvtlpsstsskdllrellralglelkaerlsseell.ealeqalraravielliiDEa 100
                 + +++++ G +GtGKT ++r++  ql+++   ee  +  +v+++  + t++ + ++ l +al+ ++ + +    +ll + +   + +r    +++ DE 
  EEA20395.1 378 SGTCIYISGTPGTGKTATVREVIAQLNNAVLDEEmDDFIFVEINGMKVTDPHQSYSLLWEALKGDRVS-PSHALDLLeREFSYPSPRRVP-CVVLMDEL 474
                 689***********************87766666555555577777777**************99999.677777776777777777777.******** PP

      AAA_22 101 qhlr...seealeeL 112
                 + l    +  +++++
  EEA20395.1 475 DQLVtknQSVMYNFF 489
                 **9765435555554 PP

>> BAH  BAH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.8   0.0   1.5e-08   1.5e-05       5      95 ..     102     200 ..      99     221 .. 0.81

  Alignments for each domain:
  == domain 1  score: 24.8 bits;  conditional E-value: 1.5e-08
                 TTGEEEEEETTSTTEEEEEEEEEEEEETTST...CEEEEEEEEEEECGGGS...TTTTHCCCT...TEEEEEEEEEEEEGGGEEEEEEEEEHHHHCTEC CS
         BAH   5 vGdfVyfddtstdepyqirrIeeLkenakne...eaeatvlvdwflrpeet...ksalklrqk...rElfltrqseilplaairgkcrVvllsdleeaq 94 
                  G +V++++ + + +  ++ I e+ e +++    e  + +++ wf+ pee    k ++k r+    +E +lt++ ++ pl++i g+ rV+++  ++   
  EEA20395.1 102 LGNVVLLKSPE-AGKDWVGLITEFVEEEDEDddeEMIKSANIMWFASPEEFssaKTKKKKRADalpNEQYLTADFNVNPLTSINGRGRVMSKDAFFAKY 199
                 67888888888.77788999999977777775557778888**********765555555555999************************998877655 PP

                 C CS
         BAH  95 n 95 
                 +
  EEA20395.1 200 P 200
                 5 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.0   3.9e-06    0.0042       4      36 ..     373     405 ..     370     423 .. 0.83

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 3.9e-06
      AAA_19   4 avealkekvllvtaGpGtGKTrvlkhivallve 36 
                 a+++ + +++ + + pGtGKT ++++++a l++
  EEA20395.1 373 AIAEGSGTCIYISGTPGTGKTATVREVIAQLNN 405
                 4557788999******************99876 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   1.1e-05     0.011      19      43 ..     381     405 ..     367     444 .. 0.77
   2 ?   -3.9   0.2       9.1   9.5e+03     155     164 ..     629     638 ..     587     668 .. 0.50

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1.1e-05
      AAA_11  19 itliqGPPGtgKTktivellsqlls 43 
                    i+G PGtgKT t+ e+++ql++
  EEA20395.1 381 CIYISGTPGTGKTATVREVIAQLNN 405
                 5689*******************63 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 9.1
      AAA_11 155 skekskskle 164
                   +ks  k e
  EEA20395.1 629 GNSKSLVKIE 638
                 1111111111 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   2.2e-05     0.023       1      35 [.     381     416 ..     381     432 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 2.2e-05
      AAA_28   1 kivitGgestGKTtlleaLaar.gypvvpEaareil 35 
                 +i+i+G+++tGKT ++++  a+ +  v+ E + +++
  EEA20395.1 381 CIYISGTPGTGKTATVREVIAQlNNAVLDEEMDDFI 416
                 59**************99988768888877776666 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   6.1e-05     0.064       3     113 ..     382     489 ..     380     524 .. 0.61

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 6.1e-05
                 EEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-...-HCHHHCCCCTS--SSS-C.......CHHHHCCSCCCEEEEEE-STT-S CS
       NACHT   3 vilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgnarsladllfsqlpepaapvse.......vwavllelperlLlilDglDelv 94 
                 + + G +G GKT+ +++++ ++    l++++ +++F+     ++   +      ll + l+     +s+        +++   ++   + ++D lD+lv
  EEA20395.1 382 IYISGTPGTGKTATVREVIAQLNNAVLDEEMDDFIFVE-INGMKVTDPH-QSYSLLWEALKGDRVSPSHaldllerEFSYPSPRRVPCVVLMDELDQLV 478
                 6799*************************987777764.3333333222.2333333333333333333222232234444444444458888888888 PP

                 S-TCH.........HHHHH CS
       NACHT  95 tdlgqkekqpvrtlLseli 113
                 t+++         ++ + +
  EEA20395.1 479 TKNQS--------VMYNFF 489
                 87776........444444 PP

>> PIF1  PIF1-like helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   6.9e-05     0.072       3      47 ..     360     404 ..     358     409 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 6.9e-05
                 -HHHHHHHHHH......HCTS-EEEEESTTSSCHHHHHHHHHHCH CS
        PIF1   3 neeQkkvfdaiieavlnekgklfFvtGsgGtgKtflwkallkklr 47 
                 n+e ++v+ +  +a+ + +g  ++++G  GtgKt   ++++++l+
  EEA20395.1 360 NAEFETVYTHLSAAIAEGSGTCIYISGTPGTGKTATVREVIAQLN 404
                 678899*****9***********************9999998876 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   0.00023      0.25       1      35 [.     382     416 ..     382     431 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00023
  RNA_helicase   1 iwlyGpsgeGKStlakeLakallkklklkkkdsvy 35 
                   i+++G +g+GK+ +++e++++l +++ +++ d+++
    EEA20395.1 382 IYISGTPGTGKTATVREVIAQLNNAVLDEEMDDFI 416
                   79*********************999777766665 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   0.00015      0.16       1      25 [.     382     419 ..     382     502 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00015
      AAA_18   1 IlltGtpGvGKttlakeLskrlgf.............g 25 
                 I ++GtpG+GKt   +e+   l++              
  EEA20395.1 382 IYISGTPGTGKTATVREVIAQLNNavldeemddfifvE 419
                 789***********999966665557755555445552 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   0.0    0.0017       1.8      12      46 ..     371     405 ..     364     421 .. 0.87
   2 ?    1.1   0.0       0.3   3.1e+02     120     148 ..     467     491 ..     445     508 .. 0.80

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0017
    ATPase_2  12 eeilerepneiyfiYGpegsGKtaLlkeiienled 46 
                    + +++ + ++i G  g GKta ++e+i +l++
  EEA20395.1 371 SAAIAEGSGTCIYISGTPGTGKTATVREVIAQLNN 405
                 55677889999*******************99854 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.3
    ATPase_2 120 iiiiiDelqklidlglngaellvkeLlnl 148
                  ++++Del +l+     ++++++++++n 
  EEA20395.1 467 CVVLMDELDQLV----TKNQSVMYNFFNW 491
                 79**********....5569999999985 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       6.3   6.7e+03     100     122 ..     141     163 ..     138     171 .. 0.80
   2 ?   10.4   0.0    0.0005      0.53       3      42 ..     383     428 ..     382     457 .. 0.78

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 6.3
      AAA_33 100 rivvvetdeetlkeRlakRaang 122
                  i+++ ++ee   ++++k++++ 
  EEA20395.1 141 NIMWFASPEEFSSAKTKKKKRAD 163
                 589999***99999999998863 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.0005
      AAA_33   3 llvGlpGsGKstlaerllkklgavllssdt......lrrrlfgtdq 42 
                 ++ G pG+GK+  +++++++l   +l++        +++ +++td+
  EEA20395.1 383 YISGTPGTGKTATVREVIAQLNNAVLDEEMddfifvEINGMKVTDP 428
                 778*******************888888765666665556655544 PP

>> KAP_NTPase  KAP family P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   0.00031      0.33      18      77 ..     377     439 ..     360     442 .. 0.81
   2 ?   -3.3   0.0       3.9   4.1e+03     174     190 ..     466     482 ..     463     488 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00031
  KAP_NTPase  18 atpivvgLygkWGsGKssllnkledelkefa...kpvrflfaefnawsfkggddavaellaaL 77 
                 + ++++ ++g  G+GK++ + +++ +l++     + ++f+f+e+n  + ++  ++   l +aL
  EEA20395.1 377 GSGTCIYISGTPGTGKTATVREVIAQLNNAVldeEMDDFIFVEINGMKVTDPHQSYSLLWEAL 439
                 5699************************9987776699*********9999877766666655 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 3.9
  KAP_NTPase 174 rlVvviDdLDrceteev 190
                 + Vv+ D+LD + t++ 
  EEA20395.1 466 PCVVLMDELDQLVTKNQ 482
                 579*******9987765 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00039      0.41       9      44 ..     369     404 ..     360     411 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00039
                 HHHHHHHHCHTEEEEEEESTTSSHHHHHHHHHHHTT CS
        TsaE   9 algkklakalgdvilLeGdLGaGKTtlvrglakalg 44 
                 +l +++a+  g++i+++G  G+GKT+ vr+++++l+
  EEA20395.1 369 HLSAAIAEGSGTCIYISGTPGTGKTATVREVIAQLN 404
                 4556666666999******************99985 PP

>> MEDS  MEDS: MEthanogen/methylotroph, DcmR Sensory domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0       1.9     2e+03       6      27 ..     240     261 ..     240     265 .. 0.89
   2 ?    5.1   0.0     0.018        19      14      91 ..     363     457 ..     359     460 .. 0.86
   3 ?    2.5   0.0      0.11   1.2e+02      40     109 ..     516     584 ..     480     608 .. 0.74

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 1.9
        MEDS   6 fyedeeellealvpfikaglar 27 
                 +y+++e  + +l++ ikagl+ 
  EEA20395.1 240 VYKGDEASVYNLIELIKAGLKT 261
                 799****************986 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.018
        MEDS  14 lealvpfikaglarge.kvlyvas......astldelrealrkagldvda....alesgqleildaeety......lrgggfdpermlealrral 91 
                 +e ++ +++a++a+g   ++y+ +      ++t++e+ ++l +a ld +     ++e + +++ d  + y      l+g + +p  +l+ l+r++
  EEA20395.1 363 FETVYTHLSAAIAEGSgTCIYISGtpgtgkTATVREVIAQLNNAVLDEEMddfiFVEINGMKVTDPHQSYsllweaLKGDRVSPSHALDLLEREF 457
                 6889999*********77777766*****999999999999999998887888899999999999999999999999999999999998888876 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.11
        MEDS  40 ldelrealrkagldvdaalesgqleildaeetylrgggfdpermlealrralakaladgyaglrvigemt 109
                  +++ ++l    +    ++  + +ei++++ + ++g+  dp  ++++ +r++a+   d  + l ++  ++
  EEA20395.1 516 SNKISSRLGLTRITFPGYKHTDLIEIISSRLANVPGNIVDP-DAIQFASRKVAAVSGDARRALDICRRAV 584
                 456666676777777789999989*****************.7779999999998877677777666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (805 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       875  (0.0488036); expected 358.6 (0.02)
Passed bias filter:                      653  (0.0364214); expected 358.6 (0.02)
Passed Vit filter:                        99  (0.00552178); expected 17.9 (0.001)
Passed Fwd filter:                        18  (0.00100396); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              17  [number of targets reported over threshold]
# CPU time: 0.82u 0.31s 00:00:01.12 Elapsed: 00:00:00.49
# Mc/sec: 4937.46
//
Query:       EEA20396.1  [L=468]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (468 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       337  (0.0187964); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.47
# Mc/sec: 3011.22
//
Query:       EEA20397.1  [L=168]
Description: prefoldin subunit 5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.4e-26   90.2   1.1      1e-25   89.9   1.1    1.1  1  Prefoldin        Prefoldin subunit
    0.00056   19.8   2.6      0.011   15.7   0.7    2.1  2  Prefoldin_2      Prefoldin subunit
     0.0022   18.1   0.5     0.0093   16.0   0.5    2.1  2  UvsW             ATP-dependant DNA helicase UvsW
     0.0049   17.1   3.4          1    9.6   0.8    2.1  2  Fib_alpha        Fibrinogen alpha/beta chain family
  ------ inclusion threshold ------
      0.011   16.0   0.4       0.18   12.2   0.1    2.1  2  BLOC1_2          Biogenesis of lysosome-related organelles co
      0.018   14.4   0.3      0.022   14.1   0.3    1.1  1  Dynamitin        Dynamitin
      0.024   14.9   1.1      0.056   13.7   1.1    1.7  1  PHM7_cyt         Cytosolic domain of 10TM putative phosphate 
      0.033   12.9   1.3          2    7.1   0.2    2.0  2  Tektin           Tektin family
      0.046   13.8   0.1          2    8.6   0.1    2.4  2  Erf4             Golgin subfamily A member 7/ERF4 family
      0.065   13.7   1.4        3.2    8.2   0.1    2.2  2  Snapin_Pallidin  Snapin/Pallidin
      0.083   12.9   0.1       0.68    9.9   0.1    1.9  2  Serine_rich      Serine rich protein interaction domain
        0.1   12.9   0.9         14    6.0   0.1    2.2  2  DUF4164          Domain of unknown function (DUF4164)
       0.12   12.7   2.9          1    9.8   0.4    2.2  2  CLZ              C-terminal leucine zipper domain of cyclic n
       0.12   12.5   1.0        5.5    7.2   0.3    2.1  2  Med30            Mediator complex subunit 30
       0.19   11.8   3.6        0.2   11.7   0.8    2.2  2  DUF4315          Domain of unknown function (DUF4315)
        0.2   12.3   3.0        6.4    7.4   0.2    2.6  3  BST2             Bone marrow stromal antigen 2
       0.36   10.4   1.7        9.9    5.8   0.1    2.3  2  YvrJ             YvrJ protein family
       0.48   10.5   5.0          4    7.5   1.8    2.3  2  TMF_DNA_bd       TATA element modulatory factor 1 DNA binding


Domain annotation for each model (and alignments):
>> Prefoldin  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.9   1.1   1.1e-28     1e-25       2     118 ..      33     157 ..      32     159 .. 0.96

  Alignments for each domain:
  == domain 1  score: 89.9 bits;  conditional E-value: 1.1e-28
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT.........-TT-EEEEEEETTEEEEEE--STTEEEEEEETTEEEEEEHHHHHHHHHHHHHHHHHH CS
   Prefoldin   2 keeleslqaelaqlkeaieelektletlktlkk........edegkevlvplgaglyvkaevkdtdkvlvdlGagyyveksleeAiellkkkleelekq 92 
                 ++ele l+ ++a+l++a+++++++  t+++           + ++  +lvpl+++lyvk+++ d +kv+vd+G+g+yvek+  +Aie+++kk++ele++
  EEA20397.1  33 NSELEQLTNSHAKLRAAQSKFRDCVRTINDGVVgkktpqpqSADNNSILVPLTSSLYVKGKLADREKVIVDVGTGFYVEKTTTKAIEFYNKKVKELEAN 131
                 789**************************98766789*9999999****************************************************** PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Prefoldin  93 lekleeeleklkdqittleanlaqly 118
                 +++le+ ++ ++++++ +e++l+q++
  EEA20397.1 132 ITDLEKIVQGKSTNLKIIEDALRQKV 157
                 **********************9986 PP

>> Prefoldin_2  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0     0.047        47      65      97 ..      23      55 ..      18      60 .. 0.80
   2 !   15.7   0.7   1.1e-05     0.011      41     104 ..      94     158 ..      92     160 .. 0.89

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.047
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Prefoldin_2 65 eeLeerketlekeiktlekqleklekeleelke 97
                 ++L   + +l+ e+++l+++  kl++  +++++
   EEA20397.1 23 PQLRSLQTRLNSELEQLTNSHAKLRAAQSKFRD 55
                 677778888888999999988888888888876 PP

  == domain 2  score: 15.7 bits;  conditional E-value: 1.1e-05
                  S-TT--EEEEETTEE.EEE-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCTS CS
  Prefoldin_2  41 ldedtkvyklvGdvl.vkqdkeevkeeLeerketlekeiktlekqleklekeleelkeelqkklq 104
                  l++ +kv   vG  + v+++ ++++e  +++ ++le++i+ lek  + + ++l+ +++ l++k+ 
   EEA20397.1  94 LADREKVIVDVGTGFyVEKTTTKAIEFYNKKVKELEANITDLEKIVQGKSTNLKIIEDALRQKVV 158
                  6777888889996543899*******************************************986 PP

>> UvsW  ATP-dependant DNA helicase UvsW
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0       2.9   2.9e+03      36      45 ..      60      69 ..      34      77 .. 0.61
   2 !   16.0   0.5   9.3e-06    0.0093      16      34 ..     120     138 ..     114     158 .. 0.82

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 2.9
                HHHHHHHHHH CS
        UvsW 36 VRDAlrGKia 45
                + D + GK++
  EEA20397.1 60 INDGVVGKKT 69
                4577777766 PP

  == domain 2  score: 16.0 bits;  conditional E-value: 9.3e-06
                 HHHHHTTT..S--TTHHHH CS
        UvsW  16 lYkkkkKElGaelkdtdDI 34 
                 +Y kk+KEl a+++d + I
  EEA20397.1 120 FYNKKVKELEANITDLEKI 138
                 8**************9988 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.4   0.1    0.0022       2.2      26      76 ..      25      76 ..      23     104 .. 0.84
   2 !    9.6   0.8     0.001         1      87     128 ..     115     156 ..      88     159 .. 0.60

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0022
                CCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH.H CS
   Fib_alpha 26 llkyekdvkkdlekleneleeisnstkeaeelvkeikdslrekqkskkdn.d 76
                l + ++ ++ +le+l+n+ ++++  +++ ++ v++i+d +  k++ ++++ d
  EEA20397.1 25 LRSLQTRLNSELEQLTNSHAKLRAAQSKFRDCVRTINDGVVGKKTPQPQSaD 76
                566789999*****************************99988877775432 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.001
                 HHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  87 eeeilrlketidaqesnirvLqnvlesneqkiqkLeqdidqk 128
                  + i+ +++++++ e ni  L ++++ ++ +++ +e +  qk
  EEA20397.1 115 TKAIEFYNKKVKELEANITDLEKIVQGKSTNLKIIEDALRQK 156
                 334555555555555555555555555555555555554444 PP

>> BLOC1_2  Biogenesis of lysosome-related organelles complex-1 subunit 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.25   2.5e+02      38      63 ..      24      49 ..      15      62 .. 0.58
   2 ?   12.2   0.1   0.00018      0.18      54      82 ..     112     140 ..      90     142 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.25
     BLOC1_2 38 klkdvaaslekkleklnekyeelqpy 63
                +l++    l+++le+l + +++l+  
  EEA20397.1 24 QLRSLQTRLNSELEQLTNSHAKLRAA 49
                55555556666666666666666554 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 0.00018
     BLOC1_2  54 nekyeelqpylqqidqiekqvteLeeavs 82 
                 + + ++++ y ++++++e+++t+Le++v+
  EEA20397.1 112 KTTTKAIEFYNKKVKELEANITDLEKIVQ 140
                 556789999******************97 PP

>> Dynamitin  Dynamitin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.3   2.3e-05     0.022     132     240 ..      21     155 ..       6     163 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 2.3e-05
   Dynamitin 132 a.eqleslqkqLeel.eellgedsaa.sltdaqealakrllsqleefkeskaaskkk.....................eksnkityelyyapeq..... 201
                 +  ql slq++L++  e+l +++++  + +++  +  +++ + +++ k+ + +s+++                     +                    
  EEA20397.1  21 SvPQLRSLQTRLNSElEQLTNSHAKLrAAQSKFRDCVRTINDGVVGKKTPQPQSADNnsilvpltsslyvkgkladreK--------------Vivdvg 105
                 4489********9888999999999977777777777888888888887777777779999999666666666654430..............344444 PP

   Dynamitin 202 ...........eksqqlakiaelekRLaeLEklvGlssesldelsanlkp 240
                            + +  ++k+ ele  ++ LEk+v  +s++l+ +++ l +
  EEA20397.1 106 tgfyvektttkAIEFYNKKVKELEANITDLEKIVQGKSTNLKIIEDALRQ 155
                 44444444444888899*****************9999999988777655 PP

>> PHM7_cyt  Cytosolic domain of 10TM putative phosphate transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   1.1   5.6e-05     0.056      90     127 ..     112     149 ..      19     152 .. 0.75

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 5.6e-05
    PHM7_cyt  90 gkkvdaidyyrekleeldeeieeerekvkkkplgaaFv 127
                 + ++ ai++y++k++el+++i+++++ v+ k ++   +
  EEA20397.1 112 KTTTKAIEFYNKKVKELEANITDLEKIVQGKSTNLKII 149
                 344799********************999999987665 PP

>> Tektin  Tektin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.0    0.0085       8.5     319     347 ..      29      57 ..      22      64 .. 0.58
   2 ?    7.1   0.2     0.002         2     136     174 ..     115     153 ..     109     162 .. 0.61

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0085
      Tektin 319 qyrLveEvkeleetieaLkeklaeaeasl 347
                 q rL++E+++l+++ ++L++  ++ ++ +
  EEA20397.1  29 QTRLNSELEQLTNSHAKLRAAQSKFRDCV 57 
                 55666666666666666665555554444 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.002
      Tektin 136 krtleqaeeqlrllraakhkLekdlsdKkeAleiDeecl 174
                 ++ +e  ++++++l+a   +Lek ++ K+++l+i e++l
  EEA20397.1 115 TKAIEFYNKKVKELEANITDLEKIVQGKSTNLKIIEDAL 153
                 555566666666666666666666666666666655554 PP

>> Erf4  Golgin subfamily A member 7/ERF4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0      0.11   1.1e+02      30      51 ..      49      70 ..      16      91 .. 0.80
   2 ?    8.6   0.1     0.002         2      60     106 ..     100     150 ..      94     155 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.11
        Erf4 30 seeefeeiinkiNeilaeafsp 51
                 +++f++++++iN+ ++ + +p
  EEA20397.1 49 AQSKFRDCVRTINDGVVGKKTP 70
                4788999999999887766665 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.002
        Erf4  60 nvlglltlylwslvlk...thykkklkklekyieelNeel.fkerglkiis 106
                  ++++ t++ +++ ++    +y+kk+k+le+ i +l + +  k+ +lkii+
  EEA20397.1 100 VIVDVGTGFYVEKTTTkaiEFYNKKVKELEANITDLEKIVqGKSTNLKIIE 150
                 58999****999999989999***************999988888899985 PP

>> Snapin_Pallidin  Snapin/Pallidin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   0.1    0.0032       3.2      16      51 ..      16      51 ..      13      63 .. 0.75
   2 ?    4.4   0.2      0.05        50      55      80 ..     115     140 ..     109     156 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0032
  Snapin_Pallidin 16 deldeklkelrqsQeeLleqldrlnekLkeleeaqe 51
                     d ++ ++ +lr  Q+ L+++l++l+++ ++l+ aq+
       EEA20397.1 16 DVTTLSVPQLRSLQTRLNSELEQLTNSHAKLRAAQS 51
                     556677888888999999999999888888887776 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.05
  Snapin_Pallidin  55 lpdlkeyakKLvnikkrmsslnerlq 80 
                       + ++ y kK+++++ +++ l++++q
       EEA20397.1 115 TKAIEFYNKKVKELEANITDLEKIVQ 140
                      56788888888888888888888876 PP

>> Serine_rich  Serine rich protein interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.1   0.00068      0.68      76     126 ..      26      76 ..      14      86 .. 0.86
   2 ?    0.9   0.0      0.39   3.9e+02      81     103 ..     124     146 ..     102     162 .. 0.60

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00068
  Serine_rich  76 knlqtkLrkqlqkledsdqilqetsqeLdsceWslealasdkkqekpddlD 126
                  ++lqt+L+ +l++l++s+  l  ++++  +c  +++  +  kk+++p + D
   EEA20397.1  26 RSLQTRLNSELEQLTNSHAKLRAAQSKFRDCVRTINDGVVGKKTPQPQSAD 76 
                  79**************************99999999988888888866555 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.39
  Serine_rich  81 kLrkqlqkledsdqilqetsqeL 103
                  k +++  +++d ++i+q  s++L
   EEA20397.1 124 KVKELEANITDLEKIVQGKSTNL 146
                  33333334444444444444443 PP

>> DUF4164  Domain of unknown function (DUF4164)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.1     0.014        14      42      70 ..      23      51 ..      16      62 .. 0.79
   2 ?    5.6   0.1      0.02        20      10      34 ..     125     149 ..     117     159 .. 0.81

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.014
     DUF4164 42 ealgedrsRLaeeLdqaearaarleevnr 70
                 +l++ ++RL  eL q ++  a+l ++++
  EEA20397.1 23 PQLRSLQTRLNSELEQLTNSHAKLRAAQS 51
                56888889999999998888888888875 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.02
     DUF4164  10 ltrLeaaldsLEkavdrrleaerkr 34 
                  ++Lea ++ LEk v+ + ++ +  
  EEA20397.1 125 VKELEANITDLEKIVQGKSTNLKII 149
                 689*************998887655 PP

>> CLZ  C-terminal leucine zipper domain of cyclic nucleotide-gated channels
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.4     0.001         1      39      63 ..      24      48 ..      19      53 .. 0.91
   2 ?    3.3   0.1      0.11   1.1e+02      30      61 ..     122     153 ..     110     161 .. 0.66

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.001
         CLZ 39 sLeaLqtrlarLlaeyessqrkLkq 63
                +L +Lqtrl+  l+++++s++kL++
  EEA20397.1 24 QLRSLQTRLNSELEQLTNSHAKLRA 48
                6899*******************86 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.11
         CLZ  30 eekverLessLeaLqtrlarLlaeyessqrkL 61 
                 ++kv++Le+++  L++ ++   ++++  +  L
  EEA20397.1 122 NKKVKELEANITDLEKIVQGKSTNLKIIEDAL 153
                 56788888888777776665555555555555 PP

>> Med30  Mediator complex subunit 30
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.056        56     105     143 ..      24      62 ..      15      65 .. 0.77
   2 ?    7.2   0.3    0.0055       5.5      89     136 ..     109     155 ..     108     159 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.056
       Med30 105 evkqlkeerkelleklkeknkqLkeimdqlrkllWdiNt 143
                 ++++l+ + +  le+l +  ++L+  + + r+ +  iN+
  EEA20397.1  24 QLRSLQTRLNSELEQLTNSHAKLRAAQSKFRDCVRTIND 62 
                 566677777777888888888888888888888888886 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0055
       Med30  89 yvdeekskreerkkseevkqlkeerkelleklkeknkqLkeimdqlrk 136
                 yv+++++k+ e    ++vk+l+++  +l + ++ k  +Lk i d lr+
  EEA20397.1 109 YVEKTTTKAIEFY-NKKVKELEANITDLEKIVQGKSTNLKIIEDALRQ 155
                 5666666666665.788*****************************98 PP

>> DUF4315  Domain of unknown function (DUF4315)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.1       1.3   1.3e+03      13      25 ..      43      55 ..      27      60 .. 0.60
   2 ?   11.7   0.8    0.0002       0.2       9      35 ..     110     137 ..     109     150 .. 0.85

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 1.3
     DUF4315 13 keKiselqarlke 25
                 +K  ++q ++++
  EEA20397.1 43 HAKLRAAQSKFRD 55
                3455566666654 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 0.0002
     DUF4315   9 ieKakeKise.lqarlkelekqktEaEN 35 
                 +eK+ +K+ e +++++kele+++t++E 
  EEA20397.1 110 VEKTTTKAIEfYNKKVKELEANITDLEK 137
                 58999997773688************94 PP

>> BST2  Bone marrow stromal antigen 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.3     0.044        44      24      48 ..      37      61 ..      24      78 .. 0.86
   2 ?   -1.8   0.0       4.8   4.8e+03      39      56 ..      73      90 ..      65     100 .. 0.77
   3 ?    7.4   0.2    0.0065       6.4      64      89 ..     121     146 ..     109     148 .. 0.80

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.044
                HHHHHHHHHHHHHHHHHHHHHHHHH CS
        BST2 24 rqLtqaqeslreaeaqaatcnqtvv 48
                +qLt ++ +lr a+ +   c +t+ 
  EEA20397.1 37 EQLTNSHAKLRAAQSKFRDCVRTIN 61
                5999999999999999999999976 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 4.8
                HHHHHHHHHHHHHHHHHH CS
        BST2 39 qaatcnqtvvtLkasLek 56
                q a  n+++v L++sL  
  EEA20397.1 73 QSADNNSILVPLTSSLYV 90
                667779999999999865 PP

  == domain 3  score: 7.4 bits;  conditional E-value: 0.0065
                 HHHHHHHHHHHHHHHHHHHHHHHHHC CS
        BST2  64 qqakvqelqgeikkLnqkLqdaeaev 89 
                  ++kv+el+ +i++L++ +q +++++
  EEA20397.1 121 YNKKVKELEANITDLEKIVQGKSTNL 146
                 4689**************99998876 PP

>> YvrJ  YvrJ protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.1      0.01       9.9      17      34 ..      30      47 ..      28      49 .. 0.87
   2 ?    3.9   0.2      0.04        40      19      35 ..     121     137 ..     121     138 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.01
        YvrJ 17 vRiEkkLdeLtksIeeLs 34
                +R++  L++Lt+s  +L+
  EEA20397.1 30 TRLNSELEQLTNSHAKLR 47
                79***********88886 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.04
        YvrJ  19 iEkkLdeLtksIeeLse 35 
                 ++kk +eL   I++L +
  EEA20397.1 121 YNKKVKELEANITDLEK 137
                 589************86 PP

>> TMF_DNA_bd  TATA element modulatory factor 1 DNA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.1     0.051        51      37      71 ..      31      47 ..      20      57 .. 0.45
   2 ?    7.5   1.8     0.004         4      39      73 ..     122     156 ..     111     157 .. 0.80

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.051
  TMF_DNA_bd 37 kLrkknkelekeikelkkkleklekeleeleerlk 71
                +L++++++l+++ ++l                  +
  EEA20397.1 31 RLNSELEQLTNSHAKL------------------R 47
                2333333333333322..................2 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.004
  TMF_DNA_bd  39 rkknkelekeikelkkkleklekeleeleerlkea 73 
                 +kk+kele +i++l+k ++ ++ +l+ +e+ l+++
  EEA20397.1 122 NKKVKELEANITDLEKIVQGKSTNLKIIEDALRQK 156
                 78999999999999999999999888888888775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (168 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1585  (0.0884043); expected 358.6 (0.02)
Passed bias filter:                     1084  (0.0604607); expected 358.6 (0.02)
Passed Vit filter:                       104  (0.00580066); expected 17.9 (0.001)
Passed Fwd filter:                        18  (0.00100396); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              18  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 1152.08
//
Query:       EEA20398.1  [L=641]
Description: prolyl-tRNA synthetase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.6e-31  108.2   0.0    1.2e-30  106.8   0.0    1.6  1  tRNA-synt_2b    tRNA synthetase class II core domain (G, H, P
    1.4e-10   41.2   0.0      3e-10   40.1   0.0    1.5  1  HGTP_anticodon  Anticodon binding domain
  ------ inclusion threshold ------
       0.18   12.3   0.9        7.2    7.2   0.1    2.4  2  zf-H2C2_2       Zinc-finger double domain


Domain annotation for each model (and alignments):
>> tRNA-synt_2b  tRNA synthetase class II core domain (G, H, P, S and T)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.8   0.0   2.1e-34   1.2e-30       1     176 [.     136     526 ..     136     528 .. 0.91

  Alignments for each domain:
  == domain 1  score: 106.8 bits;  conditional E-value: 2.1e-34
                   EEEEETTSEEEEE-SSSHHHHHHHHHHHEEEB.GGSSEEEEEEEEEEBTTTSTBCTTTB-SEEEEEEEEEEES.GGGHHHHHHHHHHHHHHHHHHTT CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2b   1 YkledrndreyiLkPtneetfvelirdevlrs.krLPlklyqiqtkyRdEksdsrGLlRvreFhqkdgyvfha.easlddslrdlikaisriferlg 95 
                   +k++dr++ ++ L Pt+ee +++l+    ++s k+LPl+lyqi++kyRdE++  +GLlR+reF +kd y f   ++++   ++   +a++rif +l 
    EEA20398.1 136 FKFNDRKESRFLLAPTHEEEITSLVASL-VNSyKELPLRLYQISRKYRDEARPRQGLLRGREFVMKDLYTFDYnAEQALATYEATREAYKRIFDTLK 231
                   89************************77.9**777****************9566******************8899******************** PP

                   .SCEEEEEEGTTSCBTTSEEEEEEEEETT.................................................................... CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxx.................................................................... RF
  tRNA-synt_2b  96 lefraiielmsaksadykdkkefeavses.................................................................... 124
                   +++ +   + +  ++ ++ + ef  +s +                                                                    
    EEA20398.1 232 VPYLVAAADSG--NMGGNLSHEFHFISDKgedtliscsdcdyvyneevsdgratenvfenplaapmpsetgvgtdsplaisialwtaiskdrktlvr 326
                   *9776666655..6789999999999999999999999*********************************************************** PP

                   ................................................................................................. CS
                   ................................................................................................. RF
  tRNA-synt_2b 125 ................................................................................................. 124
                                                                                                                    
    EEA20398.1 327 awyprystqdlgseprereinshavkaiakstgidldtsvenpvglwysdvkktaasgaqtdsapahkiidlydsqvapysrpplsglpedfdkaky 423
                   ************************************************************************************************* PP

                   .....................................TSEEEEEEEEEEEETHHHHHTTE...........EEECTTS.SEEE...E..EEEEEEEE CS
                   .....................................xxxxxxxxxxxxxxxxxxxxxxx...........xxxxxxx.xxxx...x..xxxxxxxx RF
  tRNA-synt_2b 125 .....................................ltkgieigtiqklgtrlserlga...........tvldenn.reks...v..imicaaig 167
                                                           ++e+g+ + lgtr+se l+a           +   e + ++++   v   m+c +ig
    EEA20398.1 424 pvefallnrfpdskdglsltrvvegekcpkcskgflhTHNAVELGHTFYLGTRYSEVLKAkvfvdssatksN---ESDsNSNKpqnVpmEMGCHGIG 517
                   ************************************99999*******************655554332110...1111112211122259****** PP

                   HHHHHHHHH CS
                   xxxxxxxxx RF
  tRNA-synt_2b 168 veRllsail 176
                   v+R++sa+ 
    EEA20398.1 518 VSRMISAVA 526
                   ******996 PP

>> HGTP_anticodon  Anticodon binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.1   0.0   5.1e-14     3e-10       3      93 ..     547     636 ..     545     637 .. 0.88

  Alignments for each domain:
  == domain 1  score: 40.1 bits;  conditional E-value: 5.1e-14
                     EEEESSSSHHHHHHHHHHHHHHHHTTT..SEEEEESSSSTHHHHHHHHHHTT-SEEEEE-HHHHHHTEEEEEETTTC.EEEEEETTHHHHHHHH CS
  HGTP_anticodon   3 vviplnekaeeleeyakklaeeLraag..irvelddsnesigkkireadllgipfavvvGekelekgtvtvrdrdtr.eqervsldelveklke 93 
                     +v+p      +le +a+ +++ Lr++    +v ldd+++++g+k+++ad++g+p++vvvG+     ++++v  r+ +  +e v++d+l++++++
      EEA20398.1 547 IVVPAR----NLESEAENVYDLLRQQTdtSDVILDDRTKHVGWKLKDADMIGYPIVVVVGKAWQWAQKLEVHCRQLDgLREDVPVDNLIDYIRS 636
                     344444....5999**********9999999*******************************9999999999995544889***********86 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.1     0.021   1.2e+02      11      25 ..     259     274 ..     251     275 .. 0.73
   2 ?    7.2   0.1    0.0012       7.2      16      26 .]     450     460 ..     442     460 .. 0.88

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.021
   zf-H2C2_2  11 ge.kpyeCplCdkaFk 25 
                 ge +   C+ Cd++++
  EEA20398.1 259 GEdTLISCSDCDYVYN 274
                 5623479******985 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0012
   zf-H2C2_2  16 eCplCdkaFkt 26 
                 +Cp+C+k F +
  EEA20398.1 450 KCPKCSKGFLH 460
                 7********86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (641 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       580  (0.0323498); expected 358.6 (0.02)
Passed bias filter:                      565  (0.0315132); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.42
# Mc/sec: 4580.16
//
Query:       EEA20399.1  [L=1120]
Description: CCAAT-box-binding transcription factor [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.5e-57  191.9   0.6    8.5e-57  191.9   0.6    3.4  4  CBF           CBF/Mak21 family
  ------ inclusion threshold ------
       0.41   10.9   6.1         14    5.9   0.0    4.1  3  Peroxin-13_N  Peroxin 13, N-terminal region


Domain annotation for each model (and alignments):
>> CBF  CBF/Mak21 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.5       0.5   4.5e+03     107     123 ..     181     213 ..     144     259 .. 0.62
   2 ?   -2.0   0.0      0.35   3.1e+03      88      97 ..     541     550 ..     464     623 .. 0.56
   3 !  191.9   0.6   9.5e-61   8.5e-57       1     169 [.     652     830 ..     652     831 .. 0.91
   4 ?   -8.0   6.4         2   1.8e+04     112     112 ..    1011    1011 ..     933    1058 .. 0.58

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.5
         CBF 107 e................ekfkdvkeeeeeekke 123
                 +                e+   v+++eeee+ke
  EEA20399.1 181 KdagqfnpeisddqvdeEQSASVDDSEEEEEKE 213
                 333334444444555544444444444333332 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.35
         CBF  88 llallsellk 97 
                 +++l +++l+
  EEA20399.1 541 IITLNQTILS 550
                 3333333333 PP

  == domain 3  score: 191.9 bits;  conditional E-value: 9.5e-61
         CBF   1 svqaLvllfqllskqkqsellsasdRFyraLYrkLldpelltsskralllnllykalkadkpvkrvaAFvKRllqlalhappsfalgllallsellkhp 99 
                 s+qaL+l++ql+ ++ q     a+dRFyr+LY++Lldp++ tssk++l+lnllyk+lk+d++vkrv+AFvKRl+q++ +++psf++g+ +l++el k+ 
  EEA20399.1 652 SIQALMLIQQLTATH-QV----AADRFYRTLYESLLDPRVATSSKQSLYLNLLYKSLKNDSSVKRVKAFVKRLVQILGLHQPSFICGVFFLIRELEKTY 745
                 79************5.66....78*************************************************************************88 PP

         CBF 100 pklkalle..........ekfkdvkeeeeeekkeek.....kkskae....sgvYdptkrdpeysnaeasslwElsllakhfhPtValf 169
                 p l +l++          e f+dv +ee++++ +e+          +    s+ Yd++krdp++snae+s+lwEl +l +hfhP+V+++
  EEA20399.1 746 PGLLSLVDqpeedesdeeEVFRDVPDEEDQQEAAETskqveR----TtkkiSDGYDARKRDPQHSNAEKSCLWELLPLLSHFHPSVSAL 830
                 8999*************999****999877666555555542....144559**********************************975 PP

  == domain 4  score: -8.0 bits;  conditional E-value: 2
         CBF  112 d 112 
                  d
  EEA20399.1 1011 D 1011
                  1 PP

>> Peroxin-13_N  Peroxin 13, N-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   2.0     0.012   1.1e+02      66     119 ..      40      93 ..      34     111 .. 0.55
   2 ?   -1.2   0.2      0.26   2.3e+03      86     119 ..     574     603 ..     543     621 .. 0.45
   3 ?    5.9   0.0    0.0016        14      62     118 ..     731     786 ..     726     796 .. 0.67

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.012
  Peroxin-13_N  66 falirllkkilskllglllekkkkekskaeefwkkfessskkke.ekeskeekkk 119
                    al  l ++i +kl  ++   ++k+++ ++++++  +++s++ + ++e++ ++k+
    EEA20399.1  40 GALANLTRNIEQKLKDGKNPANNKSQKRTDNAKTGTKKTSAN-DfKNEKNAAAKT 93 
                   578889999999999998655555555555553333333322.232222222211 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.26
  Peroxin-13_N  86 kkkkekskaeefwkkfessskkkeekeskeekkk 119
                   +++k++ ka++  kk ++s+++k+   +k+++++
    EEA20399.1 574 STDKKSWKADNG-KKGKKSDDAKA---QKSQAEH 603
                   222222222222.33333222222...1111111 PP

  == domain 3  score: 5.9 bits;  conditional E-value: 0.0016
  Peroxin-13_N  62 vlsifalirllkkilskllglllekkkkekskaeefwkkfessskkkeekeskeekk 118
                   + ++f lir l+k +  ll l+ +  ++ +s++ee+++++ ++++++e++e++++ +
    EEA20399.1 731 ICGVFFLIRELEKTYPGLLSLVDQP-EEDESDEEEVFRDVPDEEDQQEAAETSKQVE 786
                   6789*****************8555.5555555555588888886666333222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1120 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1814  (0.101177); expected 358.6 (0.02)
Passed bias filter:                      408  (0.0227564); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 1.19u 0.31s 00:00:01.50 Elapsed: 00:00:00.51
# Mc/sec: 6629.39
//
Query:       EEA20400.1  [L=490]
Description: neutral amino acid permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.5e-25   88.6  34.6    4.2e-25   88.3  34.6    1.0  1  Aa_trans  Transmembrane amino acid transporter protein


Domain annotation for each model (and alignments):
>> Aa_trans  Transmembrane amino acid transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.3  34.6   2.3e-29   4.2e-25       2     406 ..      61     458 ..      60     467 .. 0.85

  Alignments for each domain:
  == domain 1  score: 88.3 bits;  conditional E-value: 2.3e-29
    Aa_trans   2 tssalsavlnlikaivGaGvLaLPyAfkqlGlivGlillllvallslytlllLvkcsktlasgkrnksYgdlgyrllGpkg..kliidlailvqlfGvg 98 
                 t s+ ++++ l ++ +   +++ P+A + lGl++Glil+++val+ lyt+l + +      +++++++  d+g+ l+  ++    ++++++l+++ ++ 
  EEA20400.1  61 TCSWQKTAALLFSEYICLAIMSFPWAYSVLGLVPGLILTVFVALVVLYTSLTIWRFCL---RHPEIRDVCDIGQYLFWDSKiaWWATAVMFLLNNTFIQ 156
                 789***************************************************9776...4799*******96666333312568999********** PP

    Aa_trans  99 vsyliligdllpaifesffdtlllsnvyfilisaliiipLslipnlskLsylSllalvsslyyivilvlvvaelvklelkgvseetv........kkas 189
                   ++++ ++ l+++++       ++   f+ i+ +i + +sl + +s Ls +++++++++++   +l + ++ ++  ++ g+ e           ++ +
  EEA20400.1 157 GLHCLVGAEYLNTMTGH-----ATCTIAFSCIIPIISFFFSLPRTFSGLSHMATVSAFFTFIS--VLLATIFAGIEPRPAGYTEALGkpivtafpVSGT 248
                 ***************96.....7899**********************************974..4444444444434333333322345677889999 PP

    Aa_trans 190 klkglflaigiivFAftghavlleiqnelkdpskfkkmtkvlllsiilatvlyilvGlvGYltFGnevkg.nillnlpkssilivivnlllvlhlilsf 287
                 ++ + ++a+ +i ++f g+++l+++++e+k+p++f    k++ +++i+ ++++ +vG v Y+  Gn+  +  ++ +l+   +++ ++  +++  li+  
  EEA20400.1 249 TFVSGMSAFLNISYTFIGQITLPSFIAEMKEPEDFW---KSVTAVTIAEVIVFSIVGAVIYAYTGNQYMTaPAFGSLGDD-VYKKVAFSFMIPTLIFLG 343
                 9999******************************87...9***************************9886788888755.577777777777777777 PP

    Aa_trans 288 plqlhplrqvvenllikkeavagasekeapkskllrlvirlllvvityliAlsvpslakvlslvGatsstplsfilPalfhlkliktekksleklvkkk 386
                  l++++  ++v   +++    +  + +++ + + ++  i + l v++ +iA +vp+++++ s+ ++++ +++ fi+ ++ +l++   ++ + + +  + 
  EEA20400.1 344 VLYASVSARFVFLRFFEG---SRHKSQHTVVGWASWAGILAVLWVLAFIIAEIVPFFSDLESIMSSLFDSFFGFIFWGVAYLRMRAEDH-GSNFYKVRG 438
                 788888888888888775...7777899********************************************************99997.444444566 PP

    Aa_trans 387 ildlicivlglllvfyglav 406
                 i  +i +++ l+l+++gl++
  EEA20400.1 439 IRGWIGVIVNLFLIAVGLYF 458
                 77888888888888888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (490 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       896  (0.0499749); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3320.74
//
Query:       EEA20401.1  [L=485]
Description: glycine cleavage system T protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-75  254.5   0.0    1.3e-75  254.2   0.0    1.1  1  GCV_T     Aminomethyltransferase folate-binding domain
    1.9e-14   53.4   0.0    3.8e-14   52.4   0.0    1.5  1  GCV_T_C   Glycine cleavage T-protein C-terminal barrel domain


Domain annotation for each model (and alignments):
>> GCV_T  Aminomethyltransferase folate-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  254.2   0.0   1.4e-79   1.3e-75       1     257 []      77     356 ..      77     356 .. 0.92

  Alignments for each domain:
  == domain 1  score: 254.2 bits;  conditional E-value: 1.4e-79
       GCV_T   1 lydrhkalgakfvefagwemPvqYasesikaehlavreaaglfDvShmgkievsGpdaaalLqrlltndisklkpgkatytlllne.dGgvidDlivar 98 
                 lyd+h + gak+v+fag++mP+qY + s+ ++h+++re+a+lfDvShm +++++Gp+a+ lL ++++++++kl+ +++t+++ll++ +Gg+idD++++r
  EEA20401.1  77 LYDLHLKYGAKMVPFAGFDMPLQYTDLSHAESHHWTREKASLFDVSHMVQHRLTGPGALPLLMKVTPSSLDKLANNTSTLSCLLEDgTGGIIDDTVITR 175
                 79***********************************************************************************999*********** PP

       GCV_T  99 ldedefllvvnaankekdlawlekaaek.....kdldvevedvteelallalqGPkarevlskll.....gad.....lselkffsfaevela...... 176
                 ++ + f++v+na+++e+dla+l++++e+     ++ ++++e +++ +al+alqGP a +vl+  +     + d     l++l f +++e+ l+      
  EEA20401.1 176 QGPEAFYFVTNAGRREEDLAFLTAEIEAyrtehGADSIKWEILSD-RALIALQGPLAPSVLQSYIytgegE-DpaltdLNTLYFGQSRELYLQlpdgsk 272
                 **********************99999899987777899999777.7******************999861.24555599999999999888899**98 PP

       GCV_T 177 ggkkvlvsRtgytGedGfeiyipa.....eeaeelweaLleagkeegvkpaGlgArdtlRlEaglrlyghdldeettPleaglgwa 257
                  ++++l+sRtgytGedGfei+ip+     +   +++e L    ++ +++ aGl+Ard+lRlEag++lyghd+++ +tP +a lgw+
  EEA20401.1 273 TAHRLLISRTGYTGEDGFEISIPTsdgatDLPYQVTELL--ISQPDKCRLAGLAARDSLRLEAGMCLYGHDISTAQTPPTAALGWV 356
                 8888********************444444445799999..68999***************************************7 PP

>> GCV_T_C  Glycine cleavage T-protein C-terminal barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.4   0.0   4.3e-18   3.8e-14       2      78 ..     391     476 ..     390     477 .. 0.85

  Alignments for each domain:
  == domain 1  score: 52.4 bits;  conditional E-value: 4.3e-18
     GCV_T_C   2 rlvglelddgapllrggepilr.....dg....evvGhvTSgaysptl.gksialAyvkaelaklgtevevevrgkrvpaevvkkpf 78 
                 r +gl++++g + +r+g+ i++     ++    +++G +TSg +sp+l g +ia++y+k++l+k gtev v vr+k  +a+v+++p 
  EEA20401.1 391 RRIGLTIEKG-APAREGAIIVDpssitEEnktpTQIGVITSGLPSPSLgGTNIAMGYIKNGLHKKGTEVAVLVRNKLRKATVTPMPW 476
                 789****988.556******964444411455577*************668*********************************995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (485 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       288  (0.0160634); expected 358.6 (0.02)
Passed bias filter:                      279  (0.0155614); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.30s 00:00:00.81 Elapsed: 00:00:00.47
# Mc/sec: 3134.90
//
Query:       EEA20402.1  [L=615]
Description: MFS multidrug transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.7e-27   96.3  27.2    2.5e-26   92.4  23.7    2.1  2  MFS_1        Major Facilitator Superfamily
  ------ inclusion threshold ------
       0.18   11.7   0.6        2.1    8.2   0.0    3.0  3  LapA_dom     Lipopolysaccharide assembly protein A domain
       0.22   11.2   4.2        2.7    7.6   0.1    3.4  3  DUF1673      Protein of unknown function (DUF1673)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.4  23.7   4.2e-30   2.5e-26       1     339 [.     100     474 ..     100     487 .. 0.73
   2 !    6.5   7.4   0.00058       3.5      66     188 ..     419     542 ..     416     581 .. 0.72

  Alignments for each domain:
  == domain 1  score: 92.4 bits;  conditional E-value: 4.2e-30
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll.fasslwlllvlrvlqGlg 98 
                 ++l+++ + ++ s+++ al   ++e++++s++++   + ++ +++a++  +++++s+ +Gr+++l ++l+l  ++  l++ ++ ++ +++v+r+l Gl 
  EEA20402.1 100 IFLVQVSMNFNTSLYSNALG-GISEEFNVSEQAARCGAMIFLVLYAFGCELWAPWSEELGRKPILQASLFLVNIW-QLPVaLGKNFATIMVGRALGGLS 196
                 68889999999999999999.******************************************************.44442557777***********9 PP

       MFS_1  99 agalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee......... 188
                  +a+ ++ + +iad++  +++  a++++  ++  G++lgp++gg++ ++l Wr++ +i  i++ ++ +l l+l+pe++++   ++ +++          
  EEA20402.1 197 -SAGGSVTLGMIADMWEADNQQYAVAYVVFSSVGGSVLGPIIGGFCQQYLHWRWCIWIQLIFGGFVQLLHLFLVPETRSTLMIDKIARKMrksgenpni 294
                 .899**************************************************************999777776666666666666666888888877 PP

       MFS_1 189 ..............kgtgpaplvp.......awkallkdpvlwillialllf....ffgfsglltllplylqevlglsglllaglllallalvgailal 262
                               +    +   +       ++ ++l+ p +   l+ +ll     +++f+++ +++p+y  ++ g++++ ++++++++l    ++ + 
  EEA20402.1 295 ygeneltpwnerfsA----K---EiiktwmrPFHMFLTEPIV---LTLSLLSgfsdALIFMFIQSFSPIY--QQWGFDAVQQGLTFISILVGYLIAWFS 381
                 777777755533332....2...2222444467777777744...3333333123355555577788885..888888434444333333333333344 PP

       MFS_1 263 lagrlsdr...............lgrrrrlllallllllaalglallavtssavllll..vlvliGf.glgfvfpsllalasdlappeeagtasg 339
                 ++ ++ +                 +r + ll + ++l ++++g+a++ +    ++++   +++++G+  ++++++++ +++  +    ++++a+g
  EEA20402.1 382 FFPAIKRNireraakpddeiaqyESRLWWLLYTAPCLPIGLIGFAWTTMGPPLPWIASmiFVAIVGIaNYAIYMATIDYMICAYG--PYSASATG 474
                 5555443355567777777755333355556666666677777777777755555555335555999999999999999988887..56666666 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.00058
       MFS_1  66 llglllfalglllllfasslw.lllvlrvlqGlga.galfpagaaliadwfpkeergraigllsag.fslGailgpllggllasslg...Wravfyila 158
                  +gl++fa + +++   +  w + +++ ++ G++  +++++++ ++i ++ p    ++a+g  + +   l+ +l+ ++ +++   +g    +++  il 
  EEA20402.1 419 PIGLIGFAWT-TMGP--PLPWiASMIFVAIVGIANyAIYMATIDYMICAYGP--YSASATGGNGWSrDFLAGVLTIPATPFFNNIGGhyhIQYASTILF 512
                 4566666666.3333..33455678888888888889999999999999888..6888888888861455558999999***98888999666666666 PP

       MFS_1 159 ivsllafvlfllllpeepperkrkspkeee 188
                  +s+l+++ +++ ++  p+ rkr++ ++++
  EEA20402.1 513 CISFLLVLAVYVIYWKGPTLRKRSPFAQQL 542
                 66666666778999******9999988885 PP

>> LapA_dom  Lipopolysaccharide assembly protein A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.1      0.21   1.2e+03      21      42 ..     328     349 ..     327     356 .. 0.86
   2 ?    8.2   0.0   0.00035       2.1      24      61 ..     368     406 ..     365     408 .. 0.72
   3 ?   -2.9   0.1         1   6.3e+03      26      40 ..     511     525 ..     509     536 .. 0.57

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.21
    LapA_dom  21 llllvafgiGallgwllslwsy 42 
                 ++l ++++ G+  ++++++++ 
  EEA20402.1 328 IVLTLSLLSGFSDALIFMFIQS 349
                 7999*******99999999855 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.00035
    LapA_dom  24 lvafgiGallgwllslwsylrlrrelrrl.kkkikklek 61 
                 ++++++G l++w+ +++++ r+ re  ++ + +i++ e 
  EEA20402.1 368 FISILVGYLIAWFSFFPAIKRNIRERAAKpDDEIAQYES 406
                 7999************95554444443336888888876 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 1
    LapA_dom  26 afgiGallgwllslw 40 
                  f i +ll++ + ++
  EEA20402.1 511 LFCISFLLVLAVYVI 525
                 566777666655553 PP

>> DUF1673  Protein of unknown function (DUF1673)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.2      0.07   4.2e+02     147     201 ..      89     143 ..      82     145 .. 0.83
   2 ?    7.6   0.1   0.00046       2.7      20     104 ..     271     355 ..     269     398 .. 0.72
   3 ?    1.8   0.1     0.027   1.6e+02      79     101 ..     500     529 ..     482     546 .. 0.73

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.07
     DUF1673 147 lrwllrllllviflliavllillsyvesiagelqlgevvssfisgllllllwliy 201
                 + w   ++l vifl+ + +   +s +++  g + +++ vs + + +++++ ++ y
  EEA20402.1  89 PTWKKWTILTVIFLVQVSMNFNTSLYSNALGGISEEFNVSEQAARCGAMIFLVLY 143
                 678888999999999999999999999999***9888888888888886666555 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.00046
     DUF1673  20 etrksispenleadnysrakeenesseenpgwvdkrsnrillvslfftllsllvltqlGinlialligll.lsllliiltwkkqmq 104
                 etr  +  ++++  + + ++++n  +e+++++++ r ++  +++++++++ +++ t   +  + ll g+   +++++i ++++  q
  EEA20402.1 271 ETRSTLMIDKIARKMRKSGENPNIYGENELTPWNERFSAKEIIKTWMRPFHMFL-TEPIVLTLSLLSGFSdALIFMFIQSFSPIYQ 355
                 78999999999999999******9****************************96.4344466667777778444444544444333 PP

  == domain 3  score: 1.8 bits;  conditional E-value: 0.027
     DUF1673  79 i.......nlialliglllsllliiltwkk 101
                           i++ i++ll l +++++wk+
  EEA20402.1 500 GhyhiqyaSTILFCISFLLVLAVYVIYWKG 529
                 344444445677778888888888888885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (615 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       711  (0.0396564); expected 358.6 (0.02)
Passed bias filter:                      399  (0.0222544); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.44
# Mc/sec: 4172.16
//
Query:       EEA20403.1  [L=529]
Description: hypothetical protein PMAA_042490 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (529 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       507  (0.0282782); expected 358.6 (0.02)
Passed bias filter:                      391  (0.0218082); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.54u 0.24s 00:00:00.78 Elapsed: 00:00:00.41
# Mc/sec: 3858.67
//
Query:       EEA20404.1  [L=212]
Description: adenylylsulfate kinase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    6.5e-72  240.6   0.0      8e-72  240.3   0.0    1.1  1  APS_kinase  Adenylylsulphate kinase
    1.5e-05   25.2   0.0    3.5e-05   24.0   0.0    1.5  1  AAA_33      AAA domain
    5.8e-05   23.6   0.0    9.8e-05   22.9   0.0    1.5  1  AAA_18      AAA domain
     0.0047   16.4   0.0     0.0079   15.7   0.0    1.3  1  KTI12       Chromatin associated protein KTI12
     0.0068   16.8   0.0     0.0078   16.6   0.0    1.2  1  AAA_16      AAA ATPase domain
     0.0091   16.0   0.0      0.019   15.0   0.0    1.4  1  NCD2        NAB conserved region 2 (NCD2)
  ------ inclusion threshold ------
       0.04   13.1   0.2       0.15   11.2   0.1    1.8  2  G-alpha     G-protein alpha subunit
      0.045   13.1   0.0       0.21   10.9   0.0    1.9  2  6PF2K       6-phosphofructo-2-kinase
       0.11   12.3   0.1        0.2   11.4   0.1    1.4  1  AAA_29      P-loop containing region of AAA domain


Domain annotation for each model (and alignments):
>> APS_kinase  Adenylylsulphate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  240.3   0.0     4e-75     8e-72       1     155 [.      24     186 ..      24     189 .. 0.95

  Alignments for each domain:
  == domain 1  score: 240.3 bits;  conditional E-value: 4e-75
                 S-EEEEEESSTTSSHHHHHHHHHHHHHHTT.--EEEEEHHHHTTTTTTT--SSHHHHHHHHHHHHHHHHHHHHTT-EEEEE----SHHHHHHHHHHHHC CS
  APS_kinase   1 rgvvvwltGlsgsGKstianalekkLvekg.isvylLdGdnvRhgLnkdLgfseedRkenirrvaevaklladaglivlvafisPyreeReaarellee 98 
                 +g+++wltGls+sGKstia++le++L +++ +++y+LdGdnvR+gLnkdLgfse+dR+enirr+aevakl+ad+++i++++fisPyr++R++ar+l+e 
  EEA20404.1  24 QGLTIWLTGLSASGKSTIAVELEHQLLSTRgVHAYRLDGDNVRFGLNKDLGFSEKDRNENIRRIAEVAKLFADSTSIAITSFISPYRADRDTARQLHEA 122
                 689*********************9876544******************************************************************96 PP

                 H.......TEEEEEEEE--HHHHHHHTTTSHHHHHHTTSSSSHTTTSS-----SS-SEEEETTT CS
  APS_kinase  99 a.......lkfievfvdtplevceerDpkglYkkareGeikeftGidspYeaPenpelvvdtdk 155
                         l f+ev+vd+p+ev+e+rDpkglYkkareG ikeftGi++pYeaP +pe+++++++
  EEA20404.1 123 PtpgeetgLPFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGISAPYEAPIKPEVHIKNHE 186
                 5677777899**************************************************9876 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.0   0.0   1.7e-08   3.5e-05       2     115 ..      28     149 ..      28     166 .. 0.70

  Alignments for each domain:
  == domain 1  score: 24.0 bits;  conditional E-value: 1.7e-08
      AAA_33   2 vllvGlpGsGKstlaerllkklg......avllssdtlrrrlfgtdqqsktdytrvldrlyqilnelarkalsagrnvildatnls....rrerarflk 90 
                 ++l Gl++sGKst a +l  +l       a++l+ d++r+ l ++   s++d+++   r+ +   +l+++  s +++  + ++++     +r+  +   
  EEA20404.1  28 IWLTGLSASGKSTIAVELEHQLLstrgvhAYRLDGDNVRFGLNKDLGFSEKDRNENIRRIAEVA-KLFADSTSIAITSFI-SPYRAdrdtARQLHEAPT 124
                 5789***********9996665557779****************99999988777666666555.333333333333222.233331111222233334 PP

      AAA_33  91 larrlgvpvrivvvetdeetlkeRl 115
                   ++ g p+  v+v+++ e++++R 
  EEA20404.1 125 PGEETGLPFVEVYVDVPVEVAEQRD 149
                 4559999999999999999999995 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.0   4.9e-08   9.8e-05       1     106 [.      28     145 ..      28     165 .. 0.63

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 4.9e-08
      AAA_18   1 IlltGtpGvGKttlakeLskrl.gf.........gvnlrdvakenglllevdpealdeskrldedkldklldaleenssaleegknlvidghlaelese 89 
                 I+ltG +++GK+t+a eL+  l            g+n+r+               l++ + + e+ ++++++ + e ++  ++  ++ i ++++ ++ +
  EEA20404.1  28 IWLTGLSASGKSTIAVELEHQLlSTrgvhayrldGDNVRF--------------GLNKDLGFSEKDRNENIRRIAEVAKLFADSTSIAITSFISPYRAD 112
                 99****************6665222433333333333333..............444445555555555555555555544455677888888877777 PP

      AAA_18  90 aakdikk................vvLtaspeel 106
                 +++ ++                 v+++++ e+ 
  EEA20404.1 113 RDTARQLheaptpgeetglpfveVYVDVPVEVA 145
                 776666566666666666666666666666655 PP

>> KTI12  Chromatin associated protein KTI12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0     4e-06    0.0079       4      63 ..      28      89 ..      27     111 .. 0.71

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 4e-06
                EEEE--TTSSHHHHHHHHHHHH.HHTT--EEEE-THHHH.TTSS.S--GGGHHHHHHHHHHH CS
       KTI12  4 vvltGlPssGKstrakeLakal.eeekrsvvviddeslgiekds.ykdsakekalRsslrsa 63
                + ltGl +sGKst+a eL+++l + ++ + + +d + +++  ++    s+k ++   + +++
  EEA20404.1 28 IWLTGLSASGKSTIAVELEHQLlSTRGVHAYRLDGDNVRFGLNKdLGFSEKDRNENIRRIAE 89
                569***************97651669999999999999844333345555544444444444 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   3.9e-06    0.0078      19      63 ..      20      67 ..       9     160 .. 0.76

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 3.9e-06
      AAA_16 19 vrsgrpelvllsGesGvGKsslvrellralekdg.gif..lrgkcdql 63
                +r +++  + l+G s++GKs+++ el ++l  ++ +++  l g+++++
  EEA20404.1 20 LRNQQGLTIWLTGLSASGKSTIAVELEHQLLSTRgVHAyrLDGDNVRF 67
                55667799******************9999888425554577777776 PP

>> NCD2  NAB conserved region 2 (NCD2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   9.3e-06     0.019      51      93 ..     157     199 ..     149     204 .. 0.89

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 9.3e-06
        NCD2  51 rreeeirkysaiYGRfdskRkeekqLtlhevtvneaaaqlCkk 93 
                  re  i+ ++ i   +++  k+e ++  hevtv ea aq+ ++
  EEA20404.1 157 AREGVIKEFTGISAPYEAPIKPEVHIKNHEVTVQEAVAQIINY 199
                 577789999999999************************9765 PP

>> G-alpha  G-protein alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.1   7.6e-05      0.15      12      46 ..      14      50 ..       8      87 .. 0.85
   2 ?    0.1   0.0      0.18   3.5e+02     300     349 ..     149     199 ..      69     203 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 7.6e-05
                XXXXXXXXE..EEEEEEEESTTSSHHHHHHHHH..HH CS
     G-alpha 12 kaerkarkkkrevkllllGqseSGKsTilkqlk..ll 46
                ++er+  ++++ +++ l G s SGKsTi  +l+  ll
  EEA20404.1 14 RSERSSLRNQQGLTIWLTGLSASGKSTIAVELEhqLL 50
                6789999999******************988874444 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.18
                 H.CCHHHHHHHHHHHHHHCCCCCCESGGS.CEEEEEE-TT-HHHHHHHHHH CS
     G-alpha 300 grkndlesvlkylrnkFeeihkeksnnrr.kiythftsatdtkevqkvies 349
                 + k  ++++ + ++++F+ i   ++ + + +++++   +t +++v+++i+ 
  EEA20404.1 149 DPKGLYKKAREGVIKEFTGISAPYEAPIKpEVHIKNHEVTVQEAVAQIINY 199
                 344457888888888888888777644433556666668888888888876 PP

>> 6PF2K  6-phosphofructo-2-kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00011      0.21       8      53 ..      20      66 ..      13     101 .. 0.72
   2 ?   -0.2   0.0      0.26   5.3e+02     189     211 ..     181     203 ..     173     205 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00011
                HT..S-EEEEEESSTTSSHHHHHHHHH.HHHHHTT--EEEEEHHHHH CS
       6PF2K  8 nlknsklvivlvGLpargKtyiskklt.rylkwlgvrtkvFnvgkyr 53
                  +++ l i l GL a gK++i+++l  + l++ gv++   +  ++r
  EEA20404.1 20 LRNQQGLTIWLTGLSASGKSTIAVELEhQLLSTRGVHAYRLDGDNVR 66
                4567789999****************625677888877655555554 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.26
                 EEEEETTTTEEEEE---SHHHHH CS
       6PF2K 189 yIkvidvgkslvvnnvqgylqsr 211
                  Ik ++v  +  v ++++yl s+
  EEA20404.1 181 HIKNHEVTVQEAVAQIINYLDSK 203
                 58999999999999999999986 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1    0.0001       0.2      21      38 ..      23      41 ..      13      43 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.0001
      AAA_29 21 lkg.atlltGpsGsGKSTl 38
                ++g ++ ltG s sGKST+
  EEA20404.1 23 QQGlTIWLTGLSASGKSTI 41
                4677889***********8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (212 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       612  (0.0341346); expected 358.6 (0.02)
Passed bias filter:                      562  (0.0313459); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 1468.99
//
Query:       EEA20405.1  [L=389]
Description: vacuolar ATP synthase subunit c [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
   4.5e-124  414.6   0.0   5.2e-124  414.4   0.0    1.0  1  V-ATPase_C  V-ATPase subunit C


Domain annotation for each model (and alignments):
>> V-ATPase_C  V-ATPase subunit C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  414.4   0.0  2.9e-128  5.2e-124       1     370 []       7     382 ..       7     382 .. 0.95

  Alignments for each domain:
  == domain 1  score: 414.4 bits;  conditional E-value: 2.9e-128
  V-ATPase_C   1 ywLisvpg....ektseqtleelnkalskksknselykfeipdlkvgtLDsLvalsddLgKldafvesvvkKvartlaevledqkdkleenllvngksl 95 
                 y L+s+p+    +++++++le+++++++    + ++++f+ip++k+gtLD+Lv+++++L+Kl+  +++vv Kv + l+ vl ++++++++ ++vn+k++
  EEA20405.1   7 YQLLSLPTsivpSHHHDDALEAISSTIGV---DGSVSSFPIPEFKIGTLDALVQQAEELAKLEGICQAVVGKVGEALKGVLGNDEEQIQRMKTVNDKPV 102
                 77999999777777888888888888873...489**************************************************************** PP

  V-ATPase_C  96 esYltkFqWdeakypvkqslkelvdiiskevtqidedlktksaaYnelksslqalerkktgnLltrsLadlvkkedfvldseyLttllViVpknsekew 194
                 ++Yl++FqW++ ky++++s+ el+d ++ke+++id+d+++k+++Yn++k++l++l+rk+tgnL++rsLa +v+++++v+dseyL+t+l++Vp +++k++
  EEA20405.1 103 DQYLRTFQWNKVKYRADRSIGELIDLLKKEAASIDSDIRSKYSQYNQVKNTLATLQRKQTGNLASRSLASIVDPQKLVHDSEYLETHLIAVPSQQVKDF 201
                 *************************************************************************************************** PP

  V-ATPase_C 195 lksYekltdmVVPrSakklaeDneyaLftVtlfkkvveefkakarekkfivReFsydeeeleeekeeltkleaekkkqegelvrllkvnFsevfvawiH 293
                 lk+Ye+++ mVVPrSa+++aeD+e+ L++Vt fkk+  ef++kare+k+i+R+F+y e+  eee +e++++  +++k++ge +rl ++++se++++wiH
  EEA20405.1 202 LKQYETISPMVVPRSANLVAEDDEFSLYAVTTFKKYSAEFTHKARENKWIPRDFKYTETGREEEAKEVERVGGDERKLWGETIRLGRTSWSEAVMVWIH 300
                 *************************************************************************************************** PP

  V-ATPase_C 294 lkalrvFvEsvLRYGlpvnFqalllqpekkkekklreeLnklfahldss....akkgkvkkdd.sldiaglslgqqeyfpYv 370
                 + +lrvFvE+vLRYGlp +F++ ++ +++k +++++++L++++++l ++    +kkg+vkkdd ++ + +++ g ++y+ Yv
  EEA20405.1 301 VLVLRVFVETVLRYGLPLDFVSSIVRTTSKGAERAKKNLDNKYNYLAGNafgrDKKGRVKKDDpNEMQVAGEGGGADYTAYV 382
                 *********************7777778*********************999999999999995444444488999****98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (389 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       799  (0.0445647); expected 358.6 (0.02)
Passed bias filter:                      532  (0.0296726); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 2677.05
//
Query:       EEA20406.1  [L=302]
Description: thioesterase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.2e-10   39.8   0.0    7.1e-10   39.1   0.0    1.3  1  4HBT      Thioesterase superfamily


Domain annotation for each model (and alignments):
>> 4HBT  Thioesterase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.1   0.0     4e-14   7.1e-10       2      72 ..     194     263 ..     193     269 .. 0.94

  Alignments for each domain:
  == domain 1  score: 39.1 bits;  conditional E-value: 4e-14
                 SSB-HHHHHHHHHHHHHHHHHHTTSTTEEEEEEEEEEEESS-BBTTCEEEEEEEEEEEESSEEEEEEEEEE CS
        4HBT   2 GvvhgGvylallDeaagaalrslggrgilvvvvelsidflrpvrlgdeltvearvlrlgrtsavvevevrd 72 
                 G+vhgG ++++lDe+++ +++       + v+++lsid++rpv  ++ ++++a+ +r  ++ a ve ++ +
  EEA20406.1 194 GIVHGGLLATMLDEGLARCCFPVLPN-NIGVTANLSIDYRRPVIADNYIVLRATTVRHEGRKAWVEGRIET 263
                 9************************8.******************************99999999888865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (302 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       347  (0.0193541); expected 358.6 (0.02)
Passed bias filter:                      333  (0.0185733); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 2157.80
//
Query:       EEA20407.1  [L=369]
Description: transposable element tc1 transposase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.4e-13   48.5   0.1    2.1e-12   47.0   0.1    1.8  1  DDE_3          DDE superfamily endonuclease
    6.5e-10   39.1   0.5    1.7e-09   37.8   0.5    1.7  1  HTH_Tnp_Tc3_2  Transposase
     0.0015   18.3   1.6     0.0062   16.3   0.2    2.7  3  HTH_23         Homeodomain-like domain
     0.0078   16.1   0.0      0.022   14.7   0.0    1.8  1  HTH_12         Ribonuclease R winged-helix domain
     0.0092   15.7   0.1      0.023   14.5   0.1    1.6  1  HTH_38         Helix-turn-helix domain
  ------ inclusion threshold ------
      0.012   16.0   0.1         13    6.3   0.0    3.2  3  DUF4350        Domain of unknown function (DUF4350)
      0.014   16.0  11.1       0.14   12.8   0.6    3.7  4  HTH_32         Homeodomain-like domain
      0.034   13.8   1.2          7    6.4   0.1    3.0  2  HTH_33         Winged helix-turn helix
      0.042   13.9   0.0        9.1    6.5   0.0    3.0  3  HTH_7          Helix-turn-helix domain of resolvase
       0.18   12.0   0.0       0.35   11.1   0.0    1.4  1  DUF2774        Protein of unknown function (DUF2774)
       0.21   11.3   0.5       0.54   10.0   0.0    2.0  2  Sigma70_r4_2   Sigma-70, region 4


Domain annotation for each model (and alignments):
>> DDE_3  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.0   0.1   1.3e-15   2.1e-12      76     145 ..     259     324 ..     244     325 .. 0.85

  Alignments for each domain:
  == domain 1  score: 47.0 bits;  conditional E-value: 1.3e-15
       DDE_3  76 lqakkivlilDnasiHkseslrelveeeadrlellylPpySPelNpiEivwsklkrellkrrsfksldeL 145
                 +q++ + l  D+a+ H s++ ++ ++e   ++  +y+P+ SP+lNpiE vw+++k+++++  ++++ ++L
  EEA20407.1 259 QQSIYLQLMQDGAPGHASKETKKELQE--RNIYPIYWPAFSPDLNPIEAVWNWMKDWIQE--QYPNDEQL 324
                 3444666788*****************..******************************9..66666665 PP

>> HTH_Tnp_Tc3_2  Transposase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.8   0.5     1e-12   1.7e-09       8      72 .]     102     163 ..      98     163 .. 0.92

  Alignments for each domain:
  == domain 1  score: 37.8 bits;  conditional E-value: 1e-12
  HTH_Tnp_Tc3_2   8 vrkdPritlreLanelkeeGksvsreTirrrLrkaglkkrkprkkplLskknrkaRLeFAkehln 72 
                     ++ +r+ + ++++el      + ++   r L+k g+  +k+ +kp+Ls ++++ RL++A+eh+n
     EEA20407.1 102 SKRTRRMPYYKVIREL---DLPIGATALARALKKRGYTRCKALRKPPLSDEHKRVRLAWALEHVN 163
                    5778888888999999...999999999***********************************97 PP

>> HTH_23  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.2   3.8e-06    0.0062       5      35 ..      37      67 ..      33      74 .. 0.91
   2 ?   -1.1   0.1       1.1   1.8e+03      34      41 ..     306     313 ..     304     320 .. 0.80
   3 ?   -4.0   0.0         9   1.5e+04       3      15 ..     351     363 ..     351     367 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 3.8e-06
      HTH_23  5 reRlrillllaeGlsvreIAreLgvsrrTvy 35
                ++R+ril l   G ++ +IA +L++++ +v+
  EEA20407.1 37 DDRIRILTLREAGFTYLQIASQLHITHDQVQ 67
                68*************************9998 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 1.1
      HTH_23  34 vyrwlkry 41 
                 v++w k +
  EEA20407.1 306 VWNWMKDW 313
                 9*****99 PP

  == domain 3  score: -4.0 bits;  conditional E-value: 9
      HTH_23   3 sereRlrilllla 15 
                 s++ R++++ l+ 
  EEA20407.1 351 SMQARCQAVILAE 363
                 5788999887765 PP

>> HTH_12  Ribonuclease R winged-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   1.4e-05     0.022       5      36 ..     112     142 ..     110     144 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.4e-05
      HTH_12   5 kilaesdkpigakeiaeeLkkrgydigeravR 36 
                 k++ e d piga ++a  Lkkrgy    +a+R
  EEA20407.1 112 KVIRELDLPIGATALARALKKRGYTR-CKALR 142
                 6999********************86.67777 PP

>> HTH_38  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.1   1.4e-05     0.023       4      31 ..      33      60 ..      31      64 .. 0.91

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 1.4e-05
      HTH_38  4 hLsleeReeIerllaeGlslreIArrLg 31
                +L+ ++R +I +l+++G ++ +IA +L+
  EEA20407.1 33 RLNRDDRIRILTLREAGFTYLQIASQLH 60
                8999*********************997 PP

>> DUF4350  Domain of unknown function (DUF4350)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   0.0     0.008        13       2      52 ..      13      66 ..      12      69 .. 0.76
   2 ?   -1.3   0.0       1.8     3e+03      46      60 ..      86     100 ..      82     101 .. 0.83
   3 ?    5.6   0.0     0.014        22       4      27 ..     120     144 ..     119     152 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.008
     DUF4350  2 kspnGtralaelLeaqGvevrrvrkp.fd..alegedgtllvvapdlrlteeel 52
                ++p+G+r +a+  e++ +++r  r+       l +++ t+l +a++l++t++++
  EEA20407.1 13 AAPEGAREAASGGESKPYSTRLNRDDrIRilTLREAGFTYLQIASQLHITHDQV 66
                68999999999999999999755554233345555677*************887 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.8
     DUF4350  46 rlteeelaallewva 60 
                  l+ee+++++ +w +
  EEA20407.1  86 KLSEEDVDRVIDWIS 100
                 6899********976 PP

  == domain 3  score: 5.6 bits;  conditional E-value: 0.014
     DUF4350   4 pnGtralaelLeaqGvev.rrvrkp 27 
                 p G+ ala+ L+++G++  ++ rkp
  EEA20407.1 120 PIGATALARALKKRGYTRcKALRKP 144
                 6799************986666665 PP

>> HTH_32  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.0    0.0083        14      15      68 ..      16      65 ..      11      71 .. 0.74
   2 ?   12.8   0.6   8.8e-05      0.14      18      56 ..      76     130 ..      68     137 .. 0.66
   3 ?    2.6   0.7      0.13   2.1e+02      17      56 ..     130     173 ..     121     181 .. 0.67
   4 ?   -2.8   0.1       6.4     1e+04      53      60 ..     311     318 ..     306     336 .. 0.47

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0083
      HTH_32 15 egLkdrprrg..rpr..klsdevrariiallreeprWsprqlaarlaeregvkvShst 68
                eg ++++++g  +p   +l+ + r ri+ l+ e+  +++ q+a +l       + h +
  EEA20407.1 16 EGAREAASGGesKPYstRLNRDDRIRILTLR-EA-GFTYLQIASQL------HITHDQ 65
                566666666664553778*************.77.8********99......333433 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 8.8e-05
      HTH_32  18 kdrprrgrprklsdevrariiallreep.................rWsprqlaarl 56 
                  +++ rgr++kls+e ++r+i+++   +                   ++  la++l
  EEA20407.1  76 TPKKARGRTPKLSEEDVDRVIDWIS-SSkrtrrmpyykvireldlPIGATALARAL 130
                 588999******************4.332455444444444333333555555555 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.13
      HTH_32  17 Lkdrprrg........rprklsdevrariiallreeprWsprqlaarl 56 
                 Lk r   g        +p+ lsde+++  +a++ e+  W+ +q  + l
  EEA20407.1 130 LKKR---GytrckalrKPP-LSDEHKRVRLAWALEHVNWTIEQWNRIL 173
                 4444...222223341444.999999999999977889*999976655 PP

  == domain 4  score: -2.8 bits;  conditional E-value: 6.4
      HTH_32  53 aarlaere 60 
                  ++++e++
  EEA20407.1 311 KDWIQEQY 318
                 33443333 PP

>> HTH_33  Winged helix-turn helix
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.1     0.012        20      19      54 ..      58      93 ..      44      97 .. 0.85
   2 ?    6.4   0.1    0.0043         7      23      53 ..     122     152 ..     110     155 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.012
      HTH_33 19 gvsysvsgvyrlLkrlGfsyqkPrprapkqdpeaqe 54
                ++++++ +v    + +  +++k+r r pk ++e ++
  EEA20407.1 58 QLHITHDQVQYTCQSQQATPKKARGRTPKLSEEDVD 93
                567888999999999999**************9987 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.0043
      HTH_33  23 svsgvyrlLkrlGfsyqkPrprapkqdpeaq 53 
                   + + r Lk+ G++  k+ +++p  d++++
  EEA20407.1 122 GATALARALKKRGYTRCKALRKPPLSDEHKR 152
                 55677899********************986 PP

>> HTH_7  Helix-turn-helix domain of resolvase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.0    0.0056       9.1       7      37 ..      35      65 ..      33      66 .. 0.84
   2 ?    3.9   0.0     0.036        58       1      15 [.      82      96 ..      82     100 .. 0.94
   3 ?   -3.4   0.0       6.7   1.1e+04      21      35 ..     195     209 ..     193     210 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0056
                -HHHHGGGGSSTTTT--STTTSSSS---SSS CS
       HTH_7  7 skndinrvvkLleeGisiskIAkevnisRsT 37
                +++d  r+++L+e+G +  +IA ++ i+  +
  EEA20407.1 35 NRDDRIRILTLREAGFTYLQIASQLHITHDQ 65
                56666799*****************999655 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.036
                S---SS-HHHHGGGG CS
       HTH_7  1 GRpsklskndinrvv 15
                GR +kls++d +rv+
  EEA20407.1 82 GRTPKLSEEDVDRVI 96
                9************97 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 6.7
                 T--STTTSSSS---S CS
       HTH_7  21 GisiskIAkevnisR 35 
                 G+   +++ ++ ++R
  EEA20407.1 195 GEELDDTCLRTSVAR 209
                 666678899999998 PP

>> DUF2774  Protein of unknown function (DUF2774)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00021      0.35       3      31 ..      39      67 ..      37      83 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00021
     DUF2774  3 kvqvhflhesgknFveIAkkldirakdva 31
                ++++ +l+e+g+ + +IA +l i+  +v 
  EEA20407.1 39 RIRILTLREAGFTYLQIASQLHITHDQVQ 67
                578999*****************988775 PP

>> Sigma70_r4_2  Sigma-70, region 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00033      0.54      17      40 ..      41      63 ..      32      69 .. 0.77
   2 ?   -2.3   0.3       2.3   3.8e+03      45      53 ..     124     132 ..     123     132 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00033
                  HHHHHHHTS---HHHHHHHHT--H CS
  Sigma70_r4_2 17 eifllryleglsykEIAellgise 40
                  +i++l ++ g++y +IA++l+i+ 
    EEA20407.1 41 RILTL-REAGFTYLQIASQLHITH 63
                  46666.89*************985 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 2.3
                   HHHHHHHHH CS
  Sigma70_r4_2  45 srlsRArkk 53 
                   ++l+RA+kk
    EEA20407.1 124 TALARALKK 132
                   6799***98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (369 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       574  (0.0320152); expected 358.6 (0.02)
Passed bias filter:                      449  (0.0250432); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 2627.22
//
Query:       EEA20408.1  [L=676]
Description: succinyl-CoA synthetase subunit alpha, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.1e-36  124.5   1.4      3e-19   69.3   0.2    2.4  2  Ligase_CoA     CoA-ligase
    1.1e-17   64.4   0.8    3.4e-17   62.9   0.1    2.2  2  CoA_binding    CoA binding domain
    1.6e-09   37.7   0.0    1.3e-05   25.0   0.0    2.6  2  Succ_CoA_lig   Succinyl-CoA ligase like flavodoxin domain
     0.0056   17.2   0.4      0.033   14.7   0.1    2.5  2  CoA_binding_2  CoA binding domain
  ------ inclusion threshold ------
      0.083   12.4   0.0       0.63    9.6   0.0    2.4  2  ATP-grasp_2    ATP-grasp domain
      0.089   12.5   0.4       0.14   11.9   0.4    1.2  1  DUF648         Family of unknown function (DUF648)


Domain annotation for each model (and alignments):
>> Ligase_CoA  CoA-ligase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.1   0.1   4.9e-18   1.5e-14       2     151 ..     189     312 ..     188     314 .. 0.95
   2 !   69.3   0.2     1e-22     3e-19       1     152 [.     551     670 ..     551     671 .. 0.97

  Alignments for each domain:
  == domain 1  score: 54.1 bits;  conditional E-value: 4.9e-18
                 ESSHHHHHHHHHHHHHT..............T--BSEEEE-TSS--..........HHHHHHHHHHHHS-TT-SEEEEEEEESSSEHHHHHHHHHHHHH CS
  Ligase_CoA   2 vnGGtLayeamdlikealgdvasnkklknvlgseqheiidlGddaftkGrpHPmiDptkriealkklaadpevkvilldivlGygahedpaaellkaik 100
                  ++GtL+yea+  ++ a              g +q+ +i++G+d+ +         +t++i+a+k++ +d  +++i+l +++G g++e+ aae++k + 
  EEA20408.1 189 AKSGTLSYEAVGSLTRA--------------GLGQSLCIGMGGDVLA---------GTNFIDAMKIFENDLDTDGIVLVGEIG-GTAEMDAAEWIKDYH 263
                 579**************..............***************9.........***************************.*************99 PP

                 HTT...--S-EEEEEECTTHH.....HHHHHHHTTTSSEEE-SSHHHHHHH CS
  Ligase_CoA 101 eakaegrelpvvarvaGteadpqelseqakaleeagveiasskaqalraak 151
                 +    + ++p+ a v G ea++++++++a+a    g   a +k  al+ a+
  EEA20408.1 264 KRT--ADPKPIMALVGGLEAPKGRVMGHAGAWVAPGEPDARAKYVALQKAG 312
                 998..89************************99999999888888887776 PP

  == domain 2  score: 69.3 bits;  conditional E-value: 1e-22
                 EESSHHHHHHHHHHHHHT..............T--BSEEEE-TSS--..........HHHHHHHHHHHHS-TT-SEEEEEEEESSSEHHHHHHHHHHHH CS
  Ligase_CoA   1 lvnGGtLayeamdlikealgdvasnkklknvlgseqheiidlGddaftkGrpHPmiDptkriealkklaadpevkvilldivlGygahedpaaellkai 99 
                 lvnG++La+ ++d++ ++              g+++++++d G+ a+t           ++ e++ +l +d +vk i+++i++G  +++++a+++++a+
  EEA20408.1 551 LVNGAGLAMNTVDALILK--------------GGKPANFLDTGGKATT----------ATVKECFSILCEDARVKTIFVNIFGGLIRCDMIAEGIMEAF 625
                 79****************..............***************6..........9**************************************** PP

                 HHTT...--S-EEEEEECTTHH.....HHHHHHHTTTSSEEE-SSHHHHHHHH CS
  Ligase_CoA 100 keakaegrelpvvarvaGteadpqelseqakaleeagveiasskaqalraaka 152
                 ke++    ++pvv+r+ Gt+++     +++k ++e+g+ + + +  +++a+k+
  EEA20408.1 626 KELD---MKIPVVVRLRGTNEE-----KGQKLIAESGLPLHAFDSFEEAAEKV 670
                 ***9...***************.....9************9999999999887 PP

>> CoA_binding  CoA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.9   0.1   1.2e-20   3.4e-17       3      95 ..      44     133 ..      43     134 .. 0.97
   2 ?   -3.4   0.0       5.3   1.6e+04       7      23 ..     211     226 ..     209     231 .. 0.66

  Alignments for each domain:
  == domain 1  score: 62.9 bits;  conditional E-value: 1.2e-20
                  TEEEEEETTTSHHHHHHHHHHHHHHECEEEEEEC-TTTTTCEETTEEEESCHHHHHHHCTTTEEEEES-HHHHHHHHHHHHHTT-SEEEEESS CS
  CoA_binding   3 dtkviviGagglgiaglyhfkeklkygikavfgvnprkvgtevlglpvyksvdeleektevdvavitvPaesaqeavdelveagikgiviite 95 
                   tkv+ +G++g+  + + + ke l+ g+k+v+gv+p+ v  e+lglp+++sv+ ++ek ++d++ i+vP ++ ++a++e++ea+i+++v+++e
   EEA20408.1  44 HTKVLYQGFTGR--QATANAKESLEWGTKIVGGVKPG-VEGEHLGLPIFPSVRVAKEKSNPDASAIYVPGDQTAQAIEEAIEAEIPLVVAVAE 133
                  59**********..***********************.999*****************99******************************998 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 5.3
                  EEETTTSHHHHHHHHHH CS
  CoA_binding   7 iviGagglgiaglyhfk 23 
                  ++iG+gg   ag ++f+
   EEA20408.1 211 LCIGMGGDVLAG-TNFI 226
                  589**9994444.4554 PP

>> Succ_CoA_lig  Succinyl-CoA ligase like flavodoxin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.0   0.0   4.4e-09   1.3e-05       1     129 [.     182     320 ..     182     329 .. 0.76
   2 !   10.2   0.0   0.00017       0.5       2     104 ..     546     654 ..     545     670 .. 0.78

  Alignments for each domain:
  == domain 1  score: 25.0 bits;  conditional E-value: 4.4e-09
  Succ_CoA_lig   1 pGkialisqSGalalalldwaasrglgfskvvslGn..eadvdvadlleylaedpetkvillylE.....sirdgrkflsaarraarkkpvvvlksG 90 
                   pG+i+++++SG+l  + + ++++ glg s ++ +G    a +++ d ++ +++d +t+ i+l+ E     +++ ++   +  +r+a  kp+ +l  G
    EEA20408.1 182 PGRIGVVAKSGTLSYEAVGSLTRAGLGQSLCIGMGGdvLAGTNFIDAMKIFENDLDTDGIVLVGEiggtaEMDAAEWIKDYHKRTADPKPIMALVGG 278
                   79*********************************944578999*******************9944332333355555566666666******999 PP

  Succ_CoA_lig  91 rseagaraaashtgalag....sdavvdaafrqaGvlrvdsle 129
                     ea +  ++ h ga ++    + ++   a+++aGv  v++ e
    EEA20408.1 279 -LEAPKGRVMGHAGAWVApgepDARAKYVALQKAGVNLVSHPE 320
                   .566677778899888762222234555667777777776655 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.00017
  Succ_CoA_lig   2 GkialisqSGalalalldwaasrglgfskvvslGnea.dvdvadlleylaedpetkvillylEs.ird....grkflsaarraarkkpvvvlksGrs 92 
                   G+i+ +    +la+  +d++  +g + ++++ +G +a   +v+++++ l ed ++k+i++ + + + +    ++  ++a +++  k pvvv   G++
    EEA20408.1 546 GSIGTLVNGAGLAMNTVDALILKGGKPANFLDTGGKAtTATVKECFSILCEDARVKTIFVNIFGgLIRcdmiAEGIMEAFKELDMKIPVVVRLRGTN 642
                   677777778888999999999999999999999886516789****************99875424445778999****************999998 PP

  Succ_CoA_lig  93 eagaraaashtg 104
                   e++ +   +++g
    EEA20408.1 643 EEKGQKLIAESG 654
                   777666555555 PP

>> CoA_binding_2  CoA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.1   1.1e-05     0.033      33     114 ..      75     164 ..      53     166 .. 0.78
   2 ?   -1.4   0.0       1.1   3.3e+03      78     106 ..     287     316 ..     280     318 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.1e-05
                    ESSS-.SEETTEES----T......T--EEEE-S-HHHHGGGHHHHHHH--SEEEE-TT....---HHHHHHHHH.TT-EEE.ES-HHHH CS
  CoA_binding_2  33 Vnpke.eeilgekvyaslae.d.pepvdlvdvftppeatpeivkealalgakavwlqpg....sedeeaaelaee.agirvvgdrCilve 114
                    V p   +e lg + ++s+   + ++++d+  +++p + t++ ++ea++++++ v+  ++         + ++++   + r+vg +C++++
     EEA20408.1  75 VKPGVeGEHLGLPIFPSVRVaKeKSNPDASAIYVPGDQTAQAIEEAIEAEIPLVVAVAEhvpvHDMLRIHSILQTqSKTRLVGANCPGII 164
                    6666658999*******9964469******************************999986654222333344443567788888888875 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 1.1
                    H--SEEEE-TT---HHHHHHHHH.TT-EEE CS
  CoA_binding_2  78 lgakavwlqpgsedeeaaelaee.agirvv 106
                    +g +++w+ pg+ d+ a  +a + ag+++v
     EEA20408.1 287 MGHAGAWVAPGEPDARAKYVALQkAGVNLV 316
                    578899*****9999988777554777766 PP

>> ATP-grasp_2  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.0   0.00021      0.63     106     196 ..     396     482 ..     382     484 .. 0.76
   2 ?   -3.8   0.0       2.6   7.6e+03     152     184 ..     639     671 ..     630     674 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00021
                  EEEEEEEEETTTTEEEEEEESSTTS-HHHHHHH-GGGEEEEEEBT..TTB--HHHHHHHHHHCT--CHHHHHHHHHHHHHHHHHHHTTEEEEE CS
  ATP-grasp_2 106 ElYlsivlDraskkvvviaSseGGvdiEevaakkPekiikvaidp..akglkeeqareiakklglekelvkkaakiikklyklfveldatlvE 196
                  ++ lsi++Dr+s+++++ +Ss G    E     +  +i     +p  +++ +++   ei+  lg e+++++++ k ++ lyk+f+  +a ++E
   EEA20408.1 396 DFHLSITVDRTSRSPCITVSS-GSKSTE-----SSLRILFNYTNPefSTNTTSAVQSEIVSFLGYETDHQETLGKYLQGLYKIFKTNEAFVLE 482
                  678899999999999888876.444333.....3334444444441156777788899******************************99887 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 2.6
                  TB--HHHHHHHHHHCT--CHHHHHHHHHHHHHH CS
  ATP-grasp_2 152 kglkeeqareiakklglekelvkkaakiikkly 184
                   g +ee+ ++++ + gl+ ++++++ ++ +k+ 
   EEA20408.1 639 RGTNEEKGQKLIAESGLPLHAFDSFEEAAEKVI 671
                  677888889999999999888888888777765 PP

>> DUF648  Family of unknown function (DUF648)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.4   4.6e-05      0.14      80     233 ..     366     524 ..     362     550 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 4.6e-05
      DUF648  80 rylLHskfhnkvl..kiklLdsae....peavrvdvektsqksaskvkfsillqsepeevekavrtpkkeFfnvrkkdyvidilthvigyllgqeqeld 172
                 r +LH k h+++   ++  ++++     pe  +  +   +   +  + +s   +s   +++  +  +++eF ++ ++  v+    +++gy +++++ l 
  EEA20408.1 366 RRFLHIKQHQAFDmlQEANIQTQAkqasPEDFHLSITVDRTSRSPCITVSSGSKSTESSLRILFNYTNPEF-STNTTSAVQSEIVSFLGYETDHQETLG 463
                 778998888876411445555555444433334444444444444444444467888888888999****5.56666666666779************* PP

      DUF648 173 dlvldtsrlsqttlnleseldftlkadkkviekklrellnies.Kksklkevlksllvdgik 233
                 ++    ++  +t++    e    +  +k ++ ++ r ++  ++ K+s   e+l ++l d + 
  EEA20408.1 464 KYLQGLYKIFKTNEAFVLETRASFSSEKNIVVHEARFGFDDAAyKSSGRHEKL-HQLRDVAA 524
                 *******999********************************99999999985.55555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (676 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       568  (0.0316805); expected 358.6 (0.02)
Passed bias filter:                      501  (0.0279436); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.63u 0.25s 00:00:00.88 Elapsed: 00:00:00.42
# Mc/sec: 4883.84
//
Query:       EEA20409.1  [L=479]
Description: C6 finger domain protein GliZ [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.2e-10   38.8   6.0    2.2e-09   37.3   6.0    1.8  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.3   6.0   1.2e-13   2.2e-09       2      37 ..       9      42 ..       8      44 .. 0.94

  Alignments for each domain:
  == domain 1  score: 37.3 bits;  conditional E-value: 1.2e-13
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfysess 37
                aCd C++ K++C++++P C+ C+ +++eC+ ys s 
  EEA20409.1  9 ACDICHQAKTRCSGGNP-CTGCRNSGAECV-YSVSN 42
                9****************.************.99875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (479 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       548  (0.030565); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3372.43
//
Query:       EEA20410.1  [L=217]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        1.1    9.2   6.6       0.17   11.8   0.9    2.1  2  Jak1_Phl  Jak1 pleckstrin homology-like domain


Domain annotation for each model (and alignments):
>> Jak1_Phl  Jak1 pleckstrin homology-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.5     0.033   5.8e+02      58      74 ..      51      67 ..      22      95 .. 0.60
   2 ?   11.8   0.9   9.7e-06      0.17      24      87 ..     153     215 ..     136     217 .] 0.77

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.033
    Jak1_Phl 58 kskekkkskkkkaeskk 74
                ++k++ ++kk+ + +++
  EEA20410.1 51 TEKKSAQKKKAAVADSW 67
                22222222222222222 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 9.7e-06
    Jak1_Phl  24 aeeppthevlvtGteGiqwrlvqeeessegeksrkskekkkskkkkaeskkkkqeekekkeekW 87 
                 ++++++   l++G  Gi+  +  ee +   ++  k+ke k+  k+k e++k +q+e++ k + W
  EEA20410.1 153 EKQTAVASRLIAGALGIRAPKRTEE-QRAYDRAMKEKEIKRRNKEKEEEAKARQDEERVKAAVW 215
                 56667777899******98666655.67777777777777777778888888899999888888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (217 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1766  (0.0984996); expected 358.6 (0.02)
Passed bias filter:                      450  (0.025099); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.40
# Mc/sec: 1639.69
//
Query:       EEA20411.1  [L=209]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
        1.3    9.0   6.9       0.16   11.9   0.9    2.1  2  Jak1_Phl   Jak1 pleckstrin homology-like domain


Domain annotation for each model (and alignments):
>> Jak1_Phl  Jak1 pleckstrin homology-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.6     0.034   6.1e+02      58      74 ..      43      59 ..      15      87 .. 0.60
   2 ?   11.9   0.9     9e-06      0.16      24      87 ..     145     207 ..     128     209 .] 0.77

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.034
    Jak1_Phl 58 kskekkkskkkkaeskk 74
                ++k++ ++kk+ + +++
  EEA20411.1 43 TEKKSAQKKKAAVADSW 59
                22222222222222222 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 9e-06
    Jak1_Phl  24 aeeppthevlvtGteGiqwrlvqeeessegeksrkskekkkskkkkaeskkkkqeekekkeekW 87 
                 ++++++   l++G  Gi+  +  ee +   ++  k+ke k+  k+k e++k +q+e++ k + W
  EEA20411.1 145 EKQTAVASRLIAGALGIRAPKRTEE-QRAYDRAMKEKEIKRRNKEKEEEAKARQDEERVKAAVW 207
                 56677777899******98666655.67777777777777777778888888899999888888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (209 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2195  (0.122427); expected 358.6 (0.02)
Passed bias filter:                      641  (0.0357521); expected 358.6 (0.02)
Passed Vit filter:                        64  (0.00356964); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 1461.02
//
Query:       EEA20412.1  [L=90]
Description: ubiquitin-like modifier SUMO, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.9e-20   71.9   0.3    3.4e-20   71.7   0.3    1.1  1  Rad60-SLD  Ubiquitin-2 like Rad60 SUMO-like
    2.3e-11   43.3   0.1    2.6e-11   43.1   0.1    1.0  1  ubiquitin  Ubiquitin family


Domain annotation for each model (and alignments):
>> Rad60-SLD  Ubiquitin-2 like Rad60 SUMO-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.7   0.3   3.7e-24   3.4e-20       5      70 ..      18      83 ..      15      85 .. 0.92

  Alignments for each domain:
  == domain 1  score: 71.7 bits;  conditional E-value: 3.7e-24
                EEESSS-.-EEEEEETTSBHHHHHHHHHHHHT----TT-EEEETTEE--TTSBGGGSS--TTEEEEE CS
   Rad60-SLD  5 lkgkdgk.evkikVkptttvskLieayrkkkgipeeqkvrLiFDGeeLdpnstvedldiedgdtidv 70
                +k  d+  ev++k+k+tt+++kL++a+++++g ++ ++vr++FDG++ +p++ +  ld++dgdt++v
  EEA20412.1 18 IKVTDNHnEVFFKIKRTTQLKKLMDAFCERQGKQA-STVRFLFDGTRVRPEDSPDTLDMQDGDTLEV 83
                444555559**************************.******************************9 PP

>> ubiquitin  Ubiquitin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.1   0.1   2.9e-15   2.6e-11       2      71 ..      17      87 ..      16      88 .. 0.95

  Alignments for each domain:
  == domain 1  score: 43.1 bits;  conditional E-value: 2.9e-15
                EEEE.TTSEEEEEEEETTSBHHHHHHHHHHHHTSSGGGEEEEETTEEE-TTSBHGGHTTSTTEEEEEEESS CS
   ubiquitin  2 tvkt.ldgkkitleveesdtveelKekiaekegipaeqqrLiysGkvLedertleeygiqdgstlhlvlrl 71
                ++k+ ++++++ +++++++++++l+++ +e++g +a+  r++++G + + e ++  +++qdg+tl+++ ++
  EEA20412.1 17 NIKVtDNHNEVFFKIKRTTQLKKLMDAFCERQGKQASTVRFLFDGTRVRPEDSPDTLDMQDGDTLEVHQEQ 87
                678879999**********************************************************9886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (90 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       564  (0.0314574); expected 358.6 (0.02)
Passed bias filter:                      468  (0.026103); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.36u 0.20s 00:00:00.56 Elapsed: 00:00:00.36
# Mc/sec: 748.76
//
Query:       EEA20413.1  [L=1068]
Description: nuclear pore complex protein Nup107, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   5.5e-145  484.3   9.6   1.1e-144  483.3   9.6    1.5  1  Nup84_Nup100  Nuclear pore protein 84 / 107
  ------ inclusion threshold ------
      0.028   14.5   3.2        1.1    9.4   1.2    3.4  3  DUF2802       Protein of unknown function (DUF2802)
        0.3   10.5  17.4       0.55    9.6  17.4    1.4  1  SDA1          SDA1
        2.2    6.4  22.3       0.18   10.0  16.2    2.0  2  Nop14         Nop14-like family


Domain annotation for each model (and alignments):
>> Nup84_Nup100  Nuclear pore protein 84 / 107
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  483.3   9.6  2.5e-148  1.1e-144       2     730 .]     227    1026 ..     226    1026 .. 0.88

  Alignments for each domain:
  == domain 1  score: 483.3 bits;  conditional E-value: 2.5e-148
                    HHHHHHHHHHHHHHHHHHHHHSS-....TTT......---SSTTS-HHHHHHHHHHH-HHHHHHHHHHHHHHHT-------SS--.S........ CS
  Nup84_Nup100    2 enlelEaktWdLlerLysdrlssa....sekseeeeellelhpyssekelveellkkdselrelqivldWLeenakepeeeeged.dele..a.r 88  
                    ++l+lE++tWdL+ +L+  ++ +a    +  ++++++ ++lh+ys++ke+++++l +d+ + e+ +v++WLe  ak++ ++ ++  ++le  a r
    EEA20413.1  227 RRLQLEVDTWDLFLNLIAADDPKAvecvN--DTRKSAFQNLHRYSTDKEIWDQFLMADNYAAECAMVMKWLEVKAKSSSQHLDTMiANLEaqAdR 319 
                    79*******************87799643..588999**************************************77777777665555355555 PP

                    ......STTHHHHHC.SSHS...............................HHSTTHHHHSGGGS-HHHHHHHHHHHHHHHHHHHTT-.HHHHHH CS
  Nup84_Nup100   89 .....ahkwenTlesikqkkrlr...........gvaas.sskekeeqlVtelDpDaplRqgrkLdpkDeederallkaifellRaGk.leeaie 165 
                         ah+w++T+esik++krlr           g +as   ++++e+l+t+lDpDa++Rq++ L+++D+++e+a++ ++++++R+G+ + +++e
    EEA20413.1  320 gsglwAHGWLYTKESIKGQKRLRawpqplepgdpGLLASmLDSDNKEPLITQLDPDAIIRQKHGLQKQDQFYEQATWLTCWKMIRQGEtWGKIQE 414 
                    88999*****************************778888999999************************************************* PP

                    HHHHTT-HHHHHHHHTTSB-B.-TTTSGGGTT.-SS-BSBTTHHHHHHHHHHHHHTSSS-HHHHHHHHHHHTS---H.HHT-SHHHHHHHHHHHH CS
  Nup84_Nup100  166 lCketgqlwraaiLeGlklyh.dpnideelde.keevegnksralWkrtcyklsknknldeyeraiyglLsGdlesvlkvcksWedhLwaylnal 258 
                    + +e+ ++wra++L+G k  +  + +++++d+ ++++++ +s++ W+ +c +l++n+n+ +ye+a+y+lLsG+ e +  vc+sW+dhL++ +n++
    EEA20413.1  415 WSQERLESWRAVSLCGSKVENqSSGVKKQADDsMTRMMNCRSQDTWRAACSALARNPNTGDYEKAVYALLSGETEPAYRVCQSWDDHLYVFYNNI 509 
                    ****************99888455555655559************************************************************** PP

                    HHHHHHHHHHH............TTSS-GGG--S-----.--H.HHHHHHHHHH.....SHHHHHSCCHHHHHHHHCS-HHHHHHHHHHTTHH-- CS
  Nup84_Nup100  259 leeqveqelrelvkkkseseelpeeklsseelvlalpkp.ass.eeilnllssl.snervreeaeeplriiqaaiIlddvdsllesladalskaa 350 
                    l +++ +++ +             +kls++ l++  + p +++ ++i + l+sl  +e +  ea++p+ +iq+ai+  ++ds++ s a+a s+++
    EEA20413.1  510 LLSRYREFCSQF-----------ARKLSHSPLAIVPFTPePMDySAIQRFLESLrAHEVIGMEARNPYVTIQSAILGRNFDSFFLSTARAASESN 593 
                    ***********8...........778888887777777777778************************************************999 PP

                    ...............---------TTSHHHHHHHHHHHHHHHHH...ST.TSS-HHHHHHHHHHHHHHHHHTT-GGGHHHHHTTGGGGGG-XXXX CS
  Nup84_Nup100  351 ...............kkdesenelleepdllRflaHlilflrllgksepeskeeeeakeniitaYislLreagkyeliplYvsfLpeeravevys 430 
                                     d+s   +++++d lR+++Hl+++ ++l +  ++s+ +e+++   + aY++ Lr+ag+++ iplYvsf+p+    +v  
    EEA20413.1  594 kaspflslipdvggtGVDSSALIAVRDKDALRIITHLYIITQSLSYTRSDSHFSETTA-LNVIAYVENLRQAGLTDWIPLYVSFMPTRLVPDVIV 687 
                    **************977889999*********************99655555555555.66669******************************* PP

                    XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX........XXXXX...................XXXXXXXXXXXXXXX CS
  Nup84_Nup100  431 kfLesitdkeeRekqLklakklgldveailkrtvervieeteseyeps........eeidiekee..........elsedesevteeDlklirsl 507 
                    ++L++  ++ +++++ kl kk+++d+ a+ +   + + ++t++ +++s        +      ++          +++  ++ev+ + ++lir+ 
    EEA20413.1  688 QVLIDTVEPPDKSRMAKLLKKHHIDIFAVQEALSDYIAKKTPKGETRSitldhivrR------DQakgvvvllpvSKKFADKEVDAKMEQLIRCA 776 
                    **************************9999999999999999977777655433220......22467788888866666889************ PP

                    XXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.....XXXXX............................XXXXXX CS
  Nup84_Nup100  508 eWllfedelyeealeqsnalirrFLlngklaaakelfkrlnpkdlikeydleeledelees............................kdelee 574 
                    eWl + +  ++  +++   l+++F++ng l  a+el+ rl+++++ +++ + ++  +  ++                            ++++++
    EEA20413.1  777 EWLAYLEADWGVFCNALEYLYKKFFVNGMLLEARELSFRLPLSEVSQKLLKYDIRASSYHEdlslldensvlrsptkspsktsrfrrpqTEDERQ 871 
                    **********************************************9988844443333335667777777777788888889999999899999 PP

                    XXXXXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXX.......XXXXXXXXXXXXXXXXXXXXXXX.......XXXXXXXXXXXX.X...XXXX CS
  Nup84_Nup100  575 eteeaareyleyealiealdaleewkkl...lsnskpkkkkqyeseklkewkqklkelvkqakeliknvLkf..gWLvdltekeeeeerkeelee 664 
                    ++ ++a  +l++e  i a+ al++++++   +++ k+    + ++ +++e+ q l++ ++qa+e+++ +L +  g L++ +      e++++l  
    EEA20413.1  872 QSYDKALVLLDLEFVIWAYIALDNFAETweaFELLKN--SVNADDVQIAELSQGLQDCIEQATEHVEALLDKdlGALTQKST----PEEDKKLAY 960 
                    9************999776666655555000444444..45677778************************64444555555....47889**** PP

                    XXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Nup84_Nup100  665 lRqlyiPelileLhsvlvsartlls.enlkealeLanvVAdeesklyevFsksgrlkellqklaesS 730 
                    +R+ y P++il+++s+l++a+ +l  + l++ +e+a v A+++  ++++F  + rl+el +++a +S
    EEA20413.1  961 IRNNYFPDIILNYLSALYYASLKLDrGLLTRNMEVAIVLAEDNL-ILDCFRHACRLRELADAMALAS 1026
                    ********************999999**************9988.*****************99887 PP

>> DUF2802  Protein of unknown function (DUF2802)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   1.2   0.00026       1.1       8      41 ..     149     183 ..     144     184 .. 0.92
   2 ?   -2.0   0.0      0.88     4e+03      27      43 ..     385     406 ..     379     412 .. 0.69
   3 ?    2.5   0.0     0.035   1.6e+02      19      40 ..     860     881 ..     843     883 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00026
     DUF2802   8 elekrlkqleerleeleqqd.pqsklYsqAiklvr 41 
                 ++ ++++  +e+l+ ++qqd +q+ +Y+ A  l++
  EEA20413.1 149 RVTRQMQAFAEKLDRFKQQDrTQDSSYQAAYSLIK 183
                 6889****************9**********9997 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.88
     DUF2802  27 dpqsklYsqAi.....klvrqG 43 
                 ++q++ Y+qA      k++rqG
  EEA20413.1 385 QKQDQFYEQATwltcwKMIRQG 406
                 5688999999633333666666 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.035
     DUF2802  19 rleeleqqdpqsklYsqAiklv 40 
                 r++  +++d+ +++Y++A+ l+
  EEA20413.1 860 RFRRPQTEDERQQSYDKALVLL 881
                 56667999**********9997 PP

>> SDA1  SDA1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6  17.4   0.00012      0.55     107     173 ..      38      94 ..      28     230 .. 0.45

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00012
        SDA1 107 esdddseedseggwidvesdeeeieesdesedeeeeeeeeeekeekeeeeeeeeeeeeeeeeeeeee 173
                 ++ddd  +d+ g   d e++ +e+++++ s+d ee++e  +e  e+e+e++ +  +++eeeeeeee 
  EEA20413.1  38 DDDDD--DDQVG---DNENSVDEMDQDE-SDDAEENDE--DEVIEDEDESNVD--DDDEEEEEEEEL 94 
                 22211..22212...2222222222222.222222222..2222222222222..222222222222 PP

>> Nop14  Nop14-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0  16.2   4.1e-05      0.18     354     413 ..      38      97 ..      13     126 .. 0.51
   2 ?   -0.9   0.3     0.078   3.5e+02     700     774 ..     867     941 ..     806     950 .. 0.61

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 4.1e-05
       Nop14 354 dfeedddlveses.eeee.eeeeedeeeeedeeeeeeeeededdlsdleseeeeeedeleee 413
                 d+++ddd+v +++ +++e +++e+d+ ee+de+e   e+ede++  d+++eeeeee+el+ e
  EEA20413.1  38 DDDDDDDQVGDNEnSVDEmDQDESDDAEENDEDEV-IEDEDESNV-DDDDEEEEEEEELTVE 97 
                 22222223322220222223333333333333332.222333333.3333344555554433 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.078
       Nop14 700 skeeseqlklsllstalsllekfaelyseksafveifepilkllkklklkkkklpeelqekleellaklerllkk 774
                 ++e ++++  +l+ + l+++  +   +++     e fe +++ +++ + +  +l++ lq+ +e++++++e+ll+k
  EEA20413.1 867 EDERQQSYDKALVLLDLEFVIWAYIALDNFAETWEAFELLKNSVNADDVQIAELSQGLQDCIEQATEHVEALLDK 941
                 333344444455555555555555555555555566666666666644889999999999999999999998887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1068 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1601  (0.0892967); expected 358.6 (0.02)
Passed bias filter:                      689  (0.0384294); expected 358.6 (0.02)
Passed Vit filter:                       106  (0.00591221); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.04u 0.39s 00:00:01.43 Elapsed: 00:00:00.56
# Mc/sec: 5779.72
//
Query:       EEA20414.1  [L=262]
Description: urea hydro-lyase/cyanamide hydratase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      3e-06   27.5   0.0    4.7e-06   26.8   0.0    1.3  1  HD        HD domain


Domain annotation for each model (and alignments):
>> HD  HD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.0   2.6e-10   4.7e-06       1     116 [.      73     190 ..      73     196 .. 0.83

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 2.6e-10
                 HHHHHHHHHHHHHHHHHHHHH............HHHHHHHHHHHHHTTTTHHHHTS..HHHHHHCTCCHHHHHHHHHHHHHHHHHHHHH........HH CS
          HD   1 rleHsleVaklarrlaedlge............eedrellllaaLlHDiGkgpfgdafekkeeefekflaHekvgaeilrevekrlgld........le 79 
                 +++Hsl+V+++++ + +++ +                e+  l +LlHDiG   ++    +k     + l+ e++g  ++ +v+  +++d        +e
  EEA20414.1  73 TYNHSLRVYYFGQAIRRYR-FgttahptrssvwGFSDEIYFLSCLLHDIGTTEENL---NK-----TRLSFEFYGGFLALDVLQHDEDDaaiapreqAE 162
                 69*************9987.45***********99999999************664...33.....336788999999999988887778999999999 PP

                 HHHHHHHTTCCHHHHHHHHHHHHCCTSCHHHHHHHHH CS
          HD  80 dvaklirehheswegkkrprglaerqlslearivkla 116
                  va++i +h++  e+           ++   ++++la
  EEA20414.1 163 SVAEAIIRHQDLCEMG---------KITVVGQLIQLA 190
                 9*********999854.........666666666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (262 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       454  (0.0253221); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1725.13
//
Query:       EEA20415.1  [L=1452]
Description: P-type calcium ATPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.5e-45  153.6  15.5    9.1e-45  152.6  10.9    2.7  2  Cation_ATPase_C  Cation transporting ATPase, C-terminus
    2.1e-38  131.7   1.0    2.1e-38  131.7   1.0    2.5  2  E1-E2_ATPase     E1-E2 ATPase
    3.1e-22   78.5   0.1    8.5e-22   77.1   0.0    1.8  2  Cation_ATPase    Cation transport ATPase (P-type)
    8.7e-18   65.4   0.0    2.3e-17   64.0   0.0    1.8  1  Hydrolase        haloacid dehalogenase-like hydrolase
    9.9e-09   34.8   0.1    3.8e-08   32.9   0.1    2.1  1  Cation_ATPase_N  Cation transporter/ATPase, N-terminus
    1.3e-05   25.1   2.0    9.6e-05   22.2   1.1    2.2  2  Hydrolase_3      haloacid dehalogenase-like hydrolase
  ------ inclusion threshold ------
       0.12   12.7   7.0       0.22   11.8   0.2    3.5  4  RskA             Anti-sigma-K factor rskA
       0.21   10.4   5.6       0.24   10.2   4.3    1.7  2  LptF_LptG        Lipopolysaccharide export system permease Lp


Domain annotation for each model (and alignments):
>> Cation_ATPase_C  Cation transporting ATPase, C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.1     0.052   1.2e+02      51     101 ..     508     552 ..     490     561 .. 0.67
   2 !  152.6  10.9     4e-48   9.1e-45       2     182 .]    1023    1206 ..    1022    1206 .. 0.92

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.052
  Cation_ATPase_C  51 lrri.liqgllqalvtllvffltlllfgisekenklssnyaqtmaFitlvls 101
                      + +  l  gll+++v ++ f++ l+++++ +++       +q++  i++v +
       EEA20415.1 508 IAKLgLAAGLLLFIVLFIKFLVQLSSYESPNDK-------GQAFLQIFIVAV 552
                      444448889999999999998888888777776.......554444444443 PP

  == domain 2  score: 152.6 bits;  conditional E-value: 4e-48
  Cation_ATPase_C    2 lplsaiqiLwinLvtDllpalaLaleppekdimkrpPrkkkepliskkmlrriliqgllqalvtllvffltlllf.gisekenkls....sn 88  
                       ++l+a+q+Lw+nL++D+++alaLa++pp +++++r+P++k++pli+  m++++++q+++q+++tl++ f++l++  +++  +++ +     +
       EEA20415.1 1023 SVLTAVQLLWVNLIMDTFAALALATDPPAPSVLERRPEPKSAPLITATMWKMVIGQAIFQLVITLILNFAGLSILsSMNVLTDPNNianaTK 1114
                       68**********************************************************************95432222222222555678 PP

  Cation_ATPase_C   89 yaqtmaFitlvlsqifnalnlrsrreslfkfsglfsnkllllaillslllqvlivyvpglnavfgtaplsleewlialllalvvllvdelvK 180 
                          t++F+t+v++qifn +n+r++++ ++ f+g+f+n+++l++ l++++ qvli++v  ++++f +++l++ ew ++l+l++++l+v+ +++
       EEA20415.1 1115 ELKTVVFNTFVWMQIFNQYNCRRLDNHFNIFEGMFRNYWFLGIQLIIIGGQVLIIFV--GGQAFAITRLNGPEWGVSLVLGAISLPVAIIIR 1204
                       8********************************************************..9****************************9999 PP

  Cation_ATPase_C  181 ll 182 
                       l+
       EEA20415.1 1205 LI 1206
                       86 PP

>> E1-E2_ATPase  E1-E2 ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  131.7   1.0   9.3e-42   2.1e-38       4     180 ..     373     580 ..     370     581 .. 0.93
   2 ?   -1.8   1.5      0.86   1.9e+03     114     155 ..     992    1031 ..     979    1046 .. 0.82

  Alignments for each domain:
  == domain 1  score: 131.7 bits;  conditional E-value: 9.3e-42
                   --EEEEE-TTS-EEEEGGG--TTSEEEEETT-B--SEEEEEEE-S.EEE-TTTS---S-EE-.................G-TTEE-TT-EEEE-EEE CS
  E1-E2_ATPase   4 pptakvirdgteeeidakelvpGDivllkagdrvpaDgrivegsa.evdesaLTGEslpvek.................ekgdmvfsGtvvvsgeak 82 
                   ++++k ir+g+++ei ++++ +GD++ll++gd vp+Dg++++g++ ++des+ TGEs   +k                 +    + sG+ v +g  k
    EEA20415.1 373 DRQVKAIRSGKTVEISVHDVLVGDVILLEPGDLVPVDGVLIQGHNvKCDESSTTGESDVLRKhsaddvmraidnheslnKLDPFILSGAKVSEGVGK 469
                   678999*********************************************************************9997777889************ PP

                   EEEEE-TTTSTTTTTSTTS--------HHHHHHHHHHHHHHHHHHHHHHHHHHS-STTTSSTT..............HHHHHHHHHHHHHS-TTHHH CS
  E1-E2_ATPase  83 avVtatgedtelgkiarlveeakskktplqkkldklgkvlvpvvlliallvflialllgksla..............eallralallvaaiPcaLpl 165
                   + Vta+g ++ +gk   +++++  ++tplq kl+ l++++++++l+++ll+f+++++++                  ++++ a++++v+a+P++Lpl
    EEA20415.1 470 FMVTAVGVHSVYGKTLMSLQDE-GQTTPLQSKLNVLAEYIAKLGLAAGLLLFIVLFIKFLVQLssyespndkgqaflQIFIVAVTVIVVAVPEGLPL 565
                   ********************98.9*****************************999955444456667777888888999***************** PP

                   HHHHHHHHHHHHHHH CS
  E1-E2_ATPase 166 avplalalgarrlak 180
                   av+lala++++r+ k
    EEA20415.1 566 AVTLALAFATTRMLK 580
                   ************987 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.86
                    HHHHHHHHHHHHHHHHHHHHHHS-STTTSSTTHHHHHHHHHH CS
  E1-E2_ATPase  114 kldklgkvlvpvvlliallvflialllgkslaeallralall 155 
                     ++k+ ++ ++v +++++l+f+ a+  g++  +++l a++ll
    EEA20415.1  992 AVKKFLQFQITVNITAVILTFVSAVASGDE--NSVLTAVQLL 1031
                    578899999999999999999998777776..7888888876 PP

>> Cation_ATPase  Cation transport ATPase (P-type)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.1   0.0   3.8e-25   8.5e-22       1      90 [.     669     759 ..     669     760 .. 0.95
   2 ?   -3.6   0.0       5.7   1.3e+04      37      55 ..    1104    1122 ..    1094    1124 .. 0.83

  Alignments for each domain:
  == domain 1  score: 77.1 bits;  conditional E-value: 3.8e-25
  Cation_ATPase   1 ilcNsaafsensekdevkllGnktEsALlvlaekl..gldteelreetkkvqeipFnssrKrmsvvlklepekkvrlyvKGApeiilkrCth 90 
                    i++Ns+af+ ++++++ +++G+ktE+ALl +a++     + +e r++ + vq +pF+s rK+m+vv+k  +e+++r++vKGA+ei++ ++t+
     EEA20415.1 669 IVLNSTAFESQEDDGRLTYVGSKTETALLTFAKDYlgLGSLNEERSNANMVQMVPFDSGRKCMAVVIKR-KEGQYRMFVKGASEILIGKSTR 759
                    789********************************988899999************************7.7****************99886 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 5.7
  Cation_ATPase   37 ldteelreetkkvqeipFn 55  
                      d++++ + tk+++++ Fn
     EEA20415.1 1104 TDPNNIANATKELKTVVFN 1122
                     689999999******9998 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.0   0.0     1e-20   2.3e-17       2     210 .]     598     950 ..     597     950 .. 0.73

  Alignments for each domain:
  == domain 1  score: 64.0 bits;  conditional E-value: 1e-20
                 SEEEEESBTTTBCHHHHHHH........HHHHHCHHHHHHHHHH.......HHCHHHHHHHHHHHHH...HHHH..HHHHHETTTE............. CS
                 xxxxxxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxxxx...xxxx..xxxxxxxxxx............. RF
   Hydrolase   2 ktvvfDkdGTLttgepsved........vivsaalalaaaletg.......sehpigkalvaaakar...sgal..tgfatfigrg............. 67 
                 +t++ Dk+GTLt+  + v+         +++  + + ++  e g       s+  +   l a ak++   s+ l  t f+  ++ g             
  EEA20415.1 598 TTICSDKTGTLTQNVMKVVAgclgtsklFFDNQKNESSQSEENGdsdagevSPSALVSGLSADAKELlldSIVLnsTAFESQEDDGrltyvgsktetal 696
                 599*********9998888855443333333333333334444488999******************98844445588888777777644444444444 PP

                 ......................HHHHTHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHH......................................... CS
                 ......................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......................................... RF
   Hydrolase  68 ......................ayaigkpewltaldippdlgaaigsaqsqgrtvall......................................... 103
                                       +                                  +                                         
  EEA20415.1 697 ltfakdylglgslneersnanmV----------------------------------Qmvpfdsgrkcmavvikrkegqyrmfvkgaseiligkstrvi 761
                 44444434333333333333330..................................355566666666666666666666666666666667777777 PP

                 ...................................................................TTHHHHHHHHHHTHHBHTTHHHHHHHHHHTTE CS
                 ...................................................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase 104 ...................................................................qaralavftiadplkvkpeaaeavasLkaagi 135
                                                                                    +  +++++ i+dp  ++p++ e v++ ++ag+
  EEA20415.1 762 nkietglssiplsddartgflnisntyasrslraigllyrdfeqwpprgaptqeddknlavfdaifmDMTLVGIVGIQDP--LRPGVTESVQQCQRAGV 858
                 7788899999999999999999*********************************************99***********..***************** PP

                 EEEEEESSEHHHHHHHHHHTT.............GGGE.SEEEEHHCES...STTTSHHHHHHHHHHHTSTGGGEEEEESSHHHHHHHHHTT CS
                 xxxxxxxxxxxxxxxxxxxxx.............xxxx.xxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase 136 evvlltgdnpetaeraanqlG.............ddyf.daviasdiet...vakpspegkvaaireLqgkpeevamVGDgvnDaaalaaAg 210
                  v ++tgdn +ta+++a+++G             ++++     +++i      a  spe+k+ ++  L   +e va+ GDg nDaaal+ A+
  EEA20415.1 859 FVRMVTGDNINTAKAIAEECGiytaggvamegpkFRKLsTKQMNQIIPRlqvLARSSPEDKKILVSALIRLGETVAVTGDGSNDAAALKTAD 950
                 *********************55555555554432222222222222225555555777777777777444888***************997 PP

>> Cation_ATPase_N  Cation transporter/ATPase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.9   0.1   1.7e-11   3.8e-08      24      69 .]     271     316 ..     268     316 .. 0.95

  Alignments for each domain:
  == domain 1  score: 32.9 bits;  conditional E-value: 1.7e-11
  Cation_ATPase_N  24 aeaaerlkkyGpNelkekkkkslwvkllkqftnplvilLlvaalvs 69 
                      + +a+r++++G N+l+ekk k++w++ + ++++ ++ilL +aa++s
       EEA20415.1 271 EVFADRRRVFGANQLPEKKVKTIWELAWIAYNDKVLILLSIAAVIS 316
                      56799***************************************98 PP

>> Hydrolase_3  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0      0.13   2.8e+02      19      55 ..     845     881 ..     828     903 .. 0.84
   2 !   22.2   1.1   4.3e-08   9.6e-05     204     255 .]     931     983 ..     920     983 .. 0.89

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.13
                  HHHHHHHHHHHTTSEEEEE-SS-HHHHHHHHHHCCCC CS
  Hydrolase_3  19 ktkeaikklkekgikvviATGRslravlpvleelgld 55 
                     e +++++ +g+ v   TG ++ +++ ++ee g+ 
   EEA20415.1 845 GVTESVQQCQRAGVFVRMVTGDNINTAKAIAEECGIY 881
                  567899**************************99975 PP

  == domain 2  score: 22.2 bits;  conditional E-value: 4.3e-08
                  GGEEEEESSGGGHHHHHHSSEEEEETTS-HHHHHHSSEEE--GGG.THHHHHH CS
  Hydrolase_3 204 eeviafGDgeNDieMLeaaglgvAmgnaseevkkaAdyvtksnne.dGVakal 255
                  e v++ GDg ND + L+ a++g+Amg a  ev k A+ ++   ++  +++ka+
   EEA20415.1 931 ETVAVTGDGSNDAAALKTADVGFAMGIAGTEVAKEASDIILMDDNfTSIVKAI 983
                  678889**********************9999999999998888889999987 PP

>> RskA  Anti-sigma-K factor rskA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.1     0.051   1.1e+02      36      85 ..     333     382 ..     248     406 .. 0.70
   2 ?   -3.2   0.0         4     9e+03      46      85 ..     550     582 ..     535     687 .. 0.61
   3 ?   -3.5   0.0         5   1.1e+04      13      35 ..    1043    1065 ..    1040    1098 .. 0.50
   4 ?   11.8   0.2   9.6e-05      0.22      19      57 ..    1301    1354 ..    1290    1402 .. 0.59

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.051
                 ..........XXXXXXXXXXXXXX..........XXXXXXXXXXXXXXXXXXX CS
        RskA  36 paararr...laaaaAaalllvlgqlavasaaldplrqsaaqaeavvavlaap 85 
                 + +   +   +a ++A ++++++g +   +++l+ +  s   ++++v  ++++
  EEA20415.1 333 RVQ---WvegVAIIVAILIVVAVGAVNDYQKELQFVKLSKKKEDRQVKAIRSG 382
                 112...13336666666666777777777777777777777777777776666 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 4
                 XXXXXXXXXXX..........XXXXXXXXXXXXXXXXXXX CS
        RskA  46 aaAaalllvlgqlavasaaldplrqsaaqaeavvavlaap 85 
                 +a+ ++++++        +  pl+ + a a a++++l ++
  EEA20415.1 550 VAVTVIVVAVP-------EGLPLAVTLALAFATTRMLKDN 582
                 44444444443.......3333333333333333333333 PP

  == domain 3  score: -3.5 bits;  conditional E-value: 5
                  T-X.................... CS
        RskA   13 laatpqaaaaaaaaaaapppaaa 35  
                  la +++++a+   +++++p++a+
  EEA20415.1 1043 LALATDPPAPSVLERRPEPKSAP 1065
                  44444444443333333333222 PP

  == domain 4  score: 11.8 bits;  conditional E-value: 9.6e-05
                  .............................XXXXXXXXXXXXXX............... CS
        RskA   19 aaaaaaaaaa.apppaaapaararr....laaaaAaalllvlg..............q 57  
                  ++a++++a++ ++++++ p+         +++ aAa++++++g              q
  EEA20415.1 1301 EPASPPPATPeSRSRNRTPR----SrsnsAFGPAAAMAGVIAGsiagwspvernpgeQ 1354
                  22222222220222222222....1355699999999999998555555554444441 PP

>> LptF_LptG  Lipopolysaccharide export system permease LptF/LptG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.1   0.0       2.4   5.3e+03     280     296 ..     340     356 ..     332     363 .. 0.68
   2 ?   10.2   4.3   0.00011      0.24       8      82 ..     508     585 ..     503     591 .. 0.81

  Alignments for each domain:
  == domain 1  score: -4.1 bits;  conditional E-value: 2.4
   LptF_LptG 280 laclvfaliaaplglvk 296
                 +a++v++li +++g+v+
  EEA20415.1 340 VAIIVAILIVVAVGAVN 356
                 56677777777766665 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.00011
   LptF_LptG   8 lkpfllvllvllfllllqdllryldll...vgkglpvgdllelilynlpyilelalPlavLlavlltfgrLaedsElt 82 
                 +  + l+ ++llf++l++++l +l+++    +kg  +  ++ + +  +  +++  lPlav la+ ++ +r+ +d+ l+
  EEA20415.1 508 IAKLGLAAGLLLFIVLFIKFLVQLSSYespNDKGQAFLQIFIVAVTVIVVAVPEGLPLAVTLALAFATTRMLKDNNLV 585
                 5555566677777777777777777665557899****************************************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1452 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       790  (0.0440627); expected 358.6 (0.02)
Passed bias filter:                      430  (0.0239835); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.95u 0.30s 00:00:01.25 Elapsed: 00:00:00.48
# Mc/sec: 9084.80
//
Query:       EEA20416.1  [L=497]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (497 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       531  (0.0296168); expected 358.6 (0.02)
Passed bias filter:                      447  (0.0249317); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3500.13
//
Query:       EEA20417.1  [L=447]
Description: tubulin beta, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.7e-68  229.6   0.0    6.5e-68  228.8   0.0    1.4  1  Tubulin          Tubulin/FtsZ family, GTPase domain
      1e-41  142.0   0.0    1.7e-41  141.3   0.0    1.3  1  Tubulin_C        Tubulin C-terminal domain
    2.7e-05   24.5   0.0    7.2e-05   23.1   0.0    1.7  1  Misat_Tub_SegII  Misato Segment II tubulin-like domain
     0.0027   17.0   0.0      0.024   13.9   0.0    2.0  2  Tubulin_2        Tubulin like
     0.0033   17.1   0.0     0.0061   16.3   0.0    1.4  1  Tubulin_3        Tubulin domain
  ------ inclusion threshold ------
        0.2   11.2   0.0       0.33   10.4   0.0    1.3  1  TrmK             tRNA (adenine(22)-N(1))-methyltransferase


Domain annotation for each model (and alignments):
>> Tubulin  Tubulin/FtsZ family, GTPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  228.8   0.0   2.2e-71   6.5e-68       1     196 [.       3     211 ..       3     212 .. 0.98

  Alignments for each domain:
  == domain 1  score: 228.8 bits;  conditional E-value: 2.2e-71
                 EEEEEEEHHHHHHHHHHHHH...HHHCH..............HHHT.....TTEEEEE....EEESBHHHHHTS-GS........EEEE--CCCCTTC- CS
     Tubulin   1 eiivigvGqcGnqignelwellakehgiqsdg..........dslesfFsesgkveyiprsvaidtdpqvlneikags..elfnpnklllgkegagnng 87 
                 ei++++ GqcGnqig ++w+ +  ehg++ +g          ++++++F+e + ++y+pr+v++d++p ++++++ag+  +lf+p+++++g++gagnn+
  EEA20417.1   3 EIVHLQTGQCGNQIGAAFWQIISAEHGLDGSGvyngssdlqlERMNVYFNEASGNKYVPRAVLVDLEPGTMDAVRAGPfgQLFRPDNFVFGQSGAGNNW 101
                 79**************************75559****************************************************************** PP

                 -TT-HHHHHHHHHHTHHHHHHHHTT-SE.SEEEEEEETTSSHHHHHHHHHHHHHHHTSTTSEEEEEEEE--.GG.G-HHHHHHHHHHHHHHHHT-SEEE CS
     Tubulin  88 aggypevgkeaaeeileeirkevekcdslqgffitaslgGGTGSGlgpvilevlkeeypkalvvtvvvlPs.efsevvvepynailalkelieesdavi 185
                 a+g+++ g+e+ +++ + +r+e+e cd+lqgf+it+slgGGTG G+g++++++++ee+p++++ t++v+Ps + s+ vvepyna l++++l+e+sd ++
  EEA20417.1 102 AKGHYTEGAELVDQVVDVVRREAEACDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATFSVVPSpKVSDTVVEPYNATLSVHQLVEHSDETF 200
                 *************************************************************************************************** PP

                 EEEHHHHHCCS CS
     Tubulin 186 vidNdaLlkil 196
                 +idN+aL++i+
  EEA20417.1 201 CIDNEALYDIC 211
                 **********9 PP

>> Tubulin_C  Tubulin C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  141.3   0.0   5.6e-45   1.7e-41       1     124 [.     261     381 ..     261     383 .. 0.99

  Alignments for each domain:
  == domain 1  score: 141.3 bits;  conditional E-value: 5.6e-45
                 TTC-EEEEEEESSSCTTTTTCS-HHHHHHHHHTCSGGGBSSSTSTTTSSEEEEEEEEEESSSHHHHHHHHHHHHHTTTS-BSTTSTTTEEEEEEECECT CS
   Tubulin_C   1 PrlhFlltsyaPlvsaekaavektsvqdvtrallepknimvkvdprkgkylaiallirGdvepkevnkavqrikekkkaqfveWiptgikvalnkkspy 99 
                 PrlhF+++++aPl+s+ + +++  +v ++t+++++pkn+m+++d r+g+yl++++l+rG+v++kev+++++++++k++++fveWip+++++al++++p 
  EEA20417.1 261 PRLHFFMVGFAPLTSRGSYSFRAVTVPELTQQMYDPKNMMAASDFRNGRYLTCSALFRGKVSMKEVEDQMRNVQNKNSSYFVEWIPNNVQTALCSVPPR 359
                 9************************************************************************************************** PP

                 -TTTSSCEEEEEEEEGGGHHHHHHH CS
   Tubulin_C 100 vkkqskvsvlmlaNttsiaelfkrl 124
                 + k+    +++++N+t+i+elfkr+
  EEA20417.1 360 GLKMA---ATFVGNSTAIQELFKRV 381
                 **999...***************98 PP

>> Misat_Tub_SegII  Misato Segment II tubulin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.1   0.0   2.4e-08   7.2e-05       1      68 [.       2      71 ..       2      84 .. 0.76

  Alignments for each domain:
  == domain 1  score: 23.1 bits;  conditional E-value: 2.4e-08
  Misat_Tub_SegII  1 rEivtlqlGnyaNyvgtHfWNtQesyf......tydeeeeesevdhdvlfregetkqgqvtytPRllivDlkgs 68
                     rEiv lq G+  N +g+ fW +  +        +y+ +++  ++++   +++   +    +y+PR+++vDl+ +
       EEA20417.1  2 REIVHLQTGQCGNQIGAAFWQIISAEHgldgsgVYNGSSD-LQLERMNVYFN---EASGNKYVPRAVLVDLEPG 71
                     8********************9766653366556666666.67766656665...345689*********9754 PP

>> Tubulin_2  Tubulin like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   0.0   7.9e-06     0.024     157     203 ..     132     176 ..     101     190 .. 0.77
   2 ?    0.6   0.0     0.086   2.6e+02      48     104 ..     297     348 ..     245     355 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 7.9e-06
   Tubulin_2 157 nvfVvgSLaGGTGSGiflDvayllrkilkeekqkvkiiglvllPdvf 203
                  + +  SL GGTG+G+   ++  +r+++++      ++ +v++P+v 
  EEA20417.1 132 GFQITHSLGGGTGAGMGTLLISKIREEFPDRMM--ATFSVVPSPKVS 176
                 567899************************997..699999999985 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.086
   Tubulin_2  48 lkdatdetaekageslksrekealsissaevdrilrnllreetasaypsieeWlppe 104
                 ++   ++ + + g++l++++ +  ++s +ev++ +rn ++++    +++  eW+p++
  EEA20417.1 297 KNMMAASDF-RNGRYLTCSALFRGKVSMKEVEDQMRNVQNKN----SSYFVEWIPNN 348
                 333333334.5788899999988999******9999996554....45788999876 PP

>> Tubulin_3  Tubulin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   2.1e-06    0.0061      63     145 ..     119     195 ..      99     242 .. 0.70

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 2.1e-06
   Tubulin_3  63 dlrpfaeecdqlrglqvftgvddaWG.GfaakylerlrdeygkksilvWvlaleeklkkkkkaklerklkklnkarslkelseq 145
                  +r  ae cd l+g+q+  +     G G ++  + ++r+e++ + + ++ +  + ++ ++        ++  n + s+++l e+
  EEA20417.1 119 VVRREAEACDCLQGFQITHSLGGGTGaGMGTLLISKIREEFPDRMMATFSVVPS-PKVSD------TVVEPYNATLSVHQLVEH 195
                 368889**************99877769***************99877755332.22221......223344555555555554 PP

>> TrmK  tRNA (adenine(22)-N(1))-methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   0.00011      0.33      31     134 ..     103     210 ..      97     225 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00011
        TrmK  31 egplesAkknvkkskleekievrlgdGlavlekedeidviviaGmGgalIaeILeegkekLkkvkrliLQpnnqeeelRewlskns...y.eikaEkil 125
                 +g + ++ + v +     + e    d l+ ++ + +++  + aGmG  lI++I ee  +++  +  ++  p+ + + +  +    s     e  +E+ +
  EEA20417.1 103 KGHYTEGAELVDQVVDVVRREAEACDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATFSVVPSPKVSDTVVEPYNATLSvhqLvEHSDETFC 201
                 67777777777777777777888899999***************************9999988888888887777666655433321002133456777 PP

        TrmK 126 eekkkiYei 134
                  +++ +Y+i
  EEA20417.1 202 IDNEALYDI 210
                 777777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (447 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       466  (0.0259914); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.53u 0.24s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 3133.84
//
Query:       EEA20418.1  [L=390]
Description: nuclear mRNA splicing factor-associated protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.2e-15   55.3   0.0    3.9e-06   26.6   0.0    3.2  2  RRM_1        RNA recognition motif. (a.k.a. RRM, RBD, or RNP 


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.5   0.0   9.5e-10   1.7e-05       1      64 [.     113     184 ..     113     186 .. 0.87
   2 !   26.6   0.0   2.2e-10   3.9e-06      12      69 ..     277     331 ..     277     332 .. 0.95

  Alignments for each domain:
  == domain 1  score: 24.5 bits;  conditional E-value: 9.5e-10
                 EEEESETTTSSHHHHHHHHHTTSCE.EE.......EEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpi.ks.......iklvrdetgkskgfafVeFeskedAekAlealngkkl 64 
                 ++++ +p d+t +e++++F k+G i ++       ik++ d  g+ kg a V +  +e+ + A++ l++ ++
  EEA20418.1 113 VYITSIPLDATLDEIRDVFCKCGVIaEEidsgrprIKMYMDDSGNFKGEALVVYFRPESVNLAIQMLDESNF 184
                 89***********************5543333333678888**************************99876 PP

  == domain 2  score: 26.6 bits;  conditional E-value: 2.2e-10
                 HHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1  12 eeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkklggrel 69 
                 ++++++  sk G+++++ l+ +    + g+  V+F ++++A+++++++ g+ +gg+++
  EEA20418.1 277 KQDIRDECSKLGDVTNVVLYDK---EPAGVVTVRFSDPDAARQCVKTMGGRFFGGTQV 331
                 589***************9997...*****************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (390 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1278  (0.0712812); expected 358.6 (0.02)
Passed bias filter:                      627  (0.0349713); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.31s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 2507.17
//
Query:       EEA20419.1  [L=363]
Description: nuclear mRNA splicing factor-associated protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      7e-12   45.0   0.0    1.5e-05   24.7   0.0    3.2  2  RRM_1        RNA recognition motif. (a.k.a. RRM, RBD, or RNP 
  ------ inclusion threshold ------
        2.7    8.7   6.9        3.2    8.4   0.1    2.3  2  U1snRNP70_N  U1 small nuclear ribonucleoprotein of 70kDa MW N


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.0   1.7e-09   1.5e-05       1      64 [.     113     184 ..     113     186 .. 0.87
   2 !   16.0   0.0   9.1e-07    0.0081      12      57 ..     277     319 ..     277     320 .. 0.95

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 1.7e-09
                 EEEESETTTSSHHHHHHHHHTTSCE.EE.......EEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpi.ks.......iklvrdetgkskgfafVeFeskedAekAlealngkkl 64 
                 ++++ +p d+t +e++++F k+G i ++       ik++ d  g+ kg a V +  +e+ + A++ l++ ++
  EEA20419.1 113 VYITSIPLDATLDEIRDVFCKCGVIaEEidsgrprIKMYMDDSGNFKGEALVVYFRPESVNLAIQMLDESNF 184
                 89***********************5543333333678888**************************99876 PP

  == domain 2  score: 16.0 bits;  conditional E-value: 9.1e-07
                 HHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHH CS
       RRM_1  12 eeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAle 57 
                 ++++++  sk G+++++ l+ +    + g+  V+F ++++A+++++
  EEA20419.1 277 KQDIRDECSKLGDVTNVVLYDK---EPAGVVTVRFSDPDAARQCVK 319
                 589***************9997...******************986 PP

>> U1snRNP70_N  U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   2.7      0.04   3.6e+02      36      80 ..      74     105 ..      51     112 .. 0.43
   2 ?    8.4   0.1   0.00036       3.2      64      92 ..     212     240 ..     185     240 .. 0.79

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.04
  U1snRNP70_N  36 itGvaaflselkedeeeqeppektetkeekkererkekkekkeek 80 
                  ++Gv              e++e+t ++  kk+r++ + ++ +++k
   EEA20419.1  74 VEGVD-------------ETEEMTRSELRKKKRKQPDDENGQKQK 105
                  22332.............333333333333333333333322222 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.00036
  U1snRNP70_N  64 ekkererkekkekkeekleealeeydPke 92 
                  + + ++ k+k  k+ +kl+++l+++d++e
   EEA20419.1 212 TNTNMRDKKKIMKRTQKLNSKLADWDDDE 240
                  5667888999999999999******9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (363 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1132  (0.0631379); expected 358.6 (0.02)
Passed bias filter:                      566  (0.031569); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.25s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 2503.34
//
Query:       EEA20420.1  [L=275]
Description: nuclear mRNA splicing factor-associated protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      1e-06   28.4   0.0    9.3e-06   25.4   0.0    2.4  1  RRM_1        RNA recognition motif. (a.k.a. RRM, RBD, or RNP 
  ------ inclusion threshold ------
       0.37   11.4   1.7       0.88   10.1   0.4    2.0  2  Porph_ging   Protein of unknown function (Porph_ging)
       0.96   10.1   6.5        2.1    9.1   0.1    2.3  2  U1snRNP70_N  U1 small nuclear ribonucleoprotein of 70kDa MW N


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.4   0.0   1.6e-09   9.3e-06       1      64 [.     113     184 ..     113     186 .. 0.87

  Alignments for each domain:
  == domain 1  score: 25.4 bits;  conditional E-value: 1.6e-09
                 EEEESETTTSSHHHHHHHHHTTSCE.EE.......EEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpi.ks.......iklvrdetgkskgfafVeFeskedAekAlealngkkl 64 
                 ++++ +p d+t +e++++F k+G i ++       ik++ d  g+ kg a V +  +e+ + A++ l++ ++
  EEA20420.1 113 VYITSIPLDATLDEIRDVFCKCGVIaEEidsgrprIKMYMDDSGNFKGEALVVYFRPESVNLAIQMLDESNF 184
                 89***********************5543333333678888**************************99876 PP

>> Porph_ging  Protein of unknown function (Porph_ging)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.4   0.00015      0.88      15      68 ..      71     121 ..      66     128 .. 0.64
   2 ?   -0.2   0.0      0.25   1.5e+03      23      45 ..     205     227 ..     188     266 .. 0.60

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00015
  Porph_ging  15 cfkAtavkeveetdfsnlrrrerreeekkekeeeeeepkevevtAWytpqiPvs 68 
                 ++k   v+e+ee++ s+lr+++r++ +++   + ++++ +++ tA y ++iP++
  EEA20420.1  71 AYKVEGVDETEEMTRSELRKKKRKQPDDE---NGQKQKRQRVNTAVYITSIPLD 121
                 56666666666666666665554444443...45555555566999*****986 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.25
  Porph_ging  23 eveetdfsnlrrrerreeekkek 45 
                 + ++   +n++ r++++  k+++
  EEA20420.1 205 KSQQDAPTNTNMRDKKKIMKRTQ 227
                 33333334433333333333333 PP

>> U1snRNP70_N  U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   2.7      0.04   2.4e+02      36      80 ..      74     105 ..      51     112 .. 0.42
   2 ?    9.1   0.1   0.00034       2.1      63      92 ..     211     240 ..     182     240 .. 0.79

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.04
  U1snRNP70_N  36 itGvaaflselkedeeeqeppektetkeekkererkekkekkeek 80 
                  ++Gv              e++e+t ++  kk+r++ + ++ +++k
   EEA20420.1  74 VEGVD-------------ETEEMTRSELRKKKRKQPDDENGQKQK 105
                  33333.............333333333333333333333322222 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.00034
  U1snRNP70_N  63 eekkererkekkekkeekleealeeydPke 92 
                   + + ++ k+k  k+ +kl+++l+++d++e
   EEA20420.1 211 PTNTNMRDKKKIMKRTQKLNSKLADWDDDE 240
                  356678889999999999999****99976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1184  (0.0660383); expected 358.6 (0.02)
Passed bias filter:                      521  (0.0290591); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.47u 0.25s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2032.61
//
Query:       EEA20421.1  [L=478]
Description: ammonium transporter (Mep2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.6e-121  405.8  28.3   1.8e-121  405.6  28.3    1.0  1  Ammonium_transp  Ammonium Transporter Family


Domain annotation for each model (and alignments):
>> Ammonium_transp  Ammonium Transporter Family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  405.6  28.3    1e-125  1.8e-121       1     399 []      38     443 ..      38     443 .. 0.98

  Alignments for each domain:
  == domain 1  score: 405.6 bits;  conditional E-value: 1e-125
                      HHHHHHHHHHHHHHHHHHHHHHHHSSGGGHHHHHHHHHHHHHHHHHHHHHTHHHHHHSSCBSSSSSCE-.......TTTTSCCGCCTTCCHHHH CS
  Ammonium_transp   1 aflllsaalvifmqagfalleaglvrsknvlnilvknlldlavvvllyvlfGyslafgkskgvsgfign.......lglsaagvqdetlldglf 87 
                      a+++ s+alv++m +g++++++gl r+k++l++++ ++++++v++++++++Gyslaf++s   +++ig          l+a +v  ++++d+lf
       EEA20421.1  38 AWIITSTALVLLMIPGVGFFYSGLARRKSALSLIWLSIMSVGVISFQWFFWGYSLAFSHS--AGKYIGDlsnfgfkDVLGAPSVGSAKIPDLLF 129
                      7**********************************************************9..77777777777766777889999********* PP

                      HHHHHHHHHHHHHHHHHHCTTTB-HHHHHHHHHHHHHHTHHHHHHHHHS.SSHHHHTT--.-SSSTTTTHHHHHHHHHHHHHHHS-STTTTGTT CS
  Ammonium_transp  88 flfqlafaataitivsgavaerikfsayllfsallgtlvyppvahwvwgeggwlaklgvliDfAgstvVHlvggvagLaaalvlgkregrfegk 181
                      +++q +faa+++++  gavaer ++ + ++f ++++t++y p+a+w+w+  gw+ +lg l DfAg+t VH+ +g a+La+ l+lgkr+g +  +
       EEA20421.1 130 AIYQGMFAAITVALAVGAVAERGRMLPCIVFMFVWSTVIYDPIACWTWNPSGWVFQLGGL-DFAGGTPVHISSGAAALAYSLMLGKRRGHG-TH 221
                      ************************************************************.****************************99.79 PP

                      TSS--GSBHHHHHHHHHHHHHHHHHHHHGGGSSSSHHHHH.HHHHHHHHHHHHHHHHHHHHHHHCSS-BHHHHHHHHHHHHHHHTTTTTTS-HH CS
  Ammonium_transp 182 eeaikghnlpfavlGtllLwfgWfgFNaGsaltankrararaavtTllAaaagaltallisrlkegkinvlglanGilAGlVAiTaacavvepw 275
                      e ++++hn++ +v+Gt++Lw+gWfgFNaGsal+an ra   aav+T+lAa++g++t++l+++  e+k++++g ++G++AGlVAiT+a ++v  w
       EEA20421.1 222 ELNYRPHNVTHVVIGTVFLWVGWFGFNAGSALSANLRAVM-AAVVTNLAASVGGVTWCLLDYRLEKKWSTVGFCSGVIAGLVAITPASGFVPAW 314
                      99*************************************9.***************************************************** PP

                      HHHHHHHHHHHHHHHHHHHHHHHHTC-CTTHHHHHHHHHHHHHHHHHHHHTSHHHC....SSHSSTTGGGT-CHHHHHHHHHHHHHHHHHHHHH CS
  Ammonium_transp 276 gAliiGlvAgvlsvlgvkklkeklkidDsldvvavHgvgGiwGllavgifaaekvv....askisggllsgegkqlvvqligilvilayafvvt 365
                      +A++ G+v+++ +++g+k lk  ++idD+ld++avHg+gGi+G l++gifaa++ +    a+ki gg+l++++ ql +ql+ ++  lay+f  +
       EEA20421.1 315 SAVVFGVVGAAACNYGTK-LKYVMGIDDALDIYAVHGIGGIVGNLLTGIFAANYIAhldgATKIPGGWLNKNYIQLAYQLADSVSGLAYSFFGS 407
                      *****************8.**********************************999************************************** PP

                      HHHHHHHHHHTT..SB--HHHHHHSHHHHHHSSSSB CS
  Ammonium_transp 366 lilllllklllg..LrvseeeeevglDvaehgetay 399
                       i+ll++++++g  Lr +ee+e +g+D ae+ge+ay
       EEA20421.1 408 CIILLIINFIPGlsLRSTEEDEIMGIDDAEIGEFAY 443
                      ************999*******************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (478 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       607  (0.0338558); expected 358.6 (0.02)
Passed bias filter:                      281  (0.0156729); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.42
# Mc/sec: 3417.31
//
Query:       EEA20422.1  [L=1370]
Description: MAP kinase kinase kinase SskB, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      1e-66  225.0   0.0    2.4e-66  223.8   0.0    1.6  1  Pkinase         Protein kinase domain
    8.2e-36  123.6   0.0    4.6e-25   88.4   0.0    2.2  2  Pkinase_Tyr     Protein tyrosine kinase
    9.3e-05   21.9   0.5     0.0052   16.1   0.5    2.6  1  Kinase-like     Kinase-like
     0.0021   16.9   0.0      0.004   16.0   0.0    1.3  1  Pkinase_fungal  Fungal protein kinase
     0.0022   18.0   0.0     0.0054   16.7   0.0    1.7  1  APH             Phosphotransferase enzyme family
     0.0084   15.2   0.0      0.015   14.4   0.0    1.3  1  Seadorna_VP7    Seadornavirus VP7
  ------ inclusion threshold ------
      0.066   13.8   0.0       0.29   11.8   0.0    2.2  1  FtsX_ECD        FtsX extracellular domain
       0.07   13.5   0.1       0.25   11.7   0.1    1.9  1  FERM_f0         N-terminal or F0 domain of Talin-head FERM
       0.15   11.4   0.4        0.4   10.0   0.0    1.9  2  Kdo             Lipopolysaccharide kinase (Kdo/WaaP) family


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  223.8   0.0   1.2e-69   2.4e-66       2     264 .]    1035    1325 ..    1034    1325 .. 0.91

  Alignments for each domain:
  == domain 1  score: 223.8 bits;  conditional E-value: 1.2e-69
                  EEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHH..HHHHHHHHHHHHHSCTTB--EEEEEEESSEEEEEEE--TTEBHHHHHHHHSS-- CS
     Pkinase    2 ekleklGeGsfGkVykaveketgkivAvKkikkekakkkke..kkvlrEikilkklkhpnivrlyevfeekdelylvleyveggeladllerkgsls 96  
                  ++ + +G G+fG+Vy a++ +++  +AvK+i+ ++ +      ++++ E+ +l+ l+hpniv +y++  + d++y+++ey++gg+la lle+ ++ +
  EEA20422.1 1035 QQGQFIGGGTFGSVYVAINLDSNFLMAVKEIRLQDPQLIPViaQQIRDEMGVLEVLDHPNIVSYYGIEVHRDKVYIFMEYCSGGSLAGLLEHGRVED 1131
                  67889***************************99887655567***********************************************9777778 PP

                  HHHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCS..............................BCTTTSCGGG CS
     Pkinase   97 eeeakkiakqilegleylHskgiiHrDlKpeNiLidekgelKitDFGlakelesssk..............................ltsfvgtseY 163 
                  e+ +  +a q+legl+ylH++giiHrD+KpeNiL+d++g++K +DFG ak + ++ k                               ++++gt+ Y
  EEA20422.1 1132 ETFIMVYALQLLEGLAYLHQAGIIHRDIKPENILLDHNGVIKYVDFGAAKIIARQGKtianteaftnavggshkeglggakepqrknQKTMTGTPMY 1228
                  88889*************************************************9999****************************99********* PP

                  S-HHHH.....TTSCBSHHHHHHHHHHHHHHHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCTSHH...HHHTTS-HHHHHHHHHHT-SSGCCSTTH CS
     Pkinase  164 lAPEvl.....keneyskkvDvWslGvilyelltgkppfsgekgkekvekeldqlekilkilgetkeklpeaseiseeakdllkkllkkdpkkRlta 255 
                  ++PEv+     +  + + ++D+WslG++++e+ tg+ p+s+ +++   ++++      ++i + ++ +lp+++++s+  +d+l++++++dp+kR+ta
  EEA20422.1 1229 MSPEVIrgdtsELADRQGAIDIWSLGCVILEMATGRRPWSSLDNE---WAIM------YNIAQGNQPQLPTREQLSDLGIDFLSRCFERDPMKRPTA 1316
                  ******7654222555889*********************33333...3333......346667899****************************** PP

                  HHHHTSGGG CS
     Pkinase  256 eellqhpyl 264 
                  +ellqh+++
  EEA20422.1 1317 AELLQHEWI 1325
                  ********7 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.4   0.0   2.3e-28   4.6e-25       3     163 ..    1036    1193 ..    1034    1199 .. 0.88
   2 !   32.9   0.0   1.9e-11   3.9e-08     158     257 ..    1215    1321 ..    1207    1322 .. 0.80

  Alignments for each domain:
  == domain 1  score: 88.4 bits;  conditional E-value: 2.3e-28
                   EEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHH...HHHHHHHHHHHHTS-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHT CS
  Pkinase_Tyr    3 lgkklGeGafGkVvegtlkgekekkevkVavKtlkeeateee...keelleeakimkklkhpnivkllgvctkeepllivteyvkgGdLlkfLrkk 95  
                    g+ +G G+fG+V+ +       +++   avK ++ +  +      +++ +e+ +++ l+hpniv+++g+ +++++++i +ey++gG+L   L++ 
   EEA20422.1 1036 QGQFIGGGTFGSVYVAINL----DSNFLMAVKEIRLQDPQLIpviAQQIRDEMGVLEVLDHPNIVSYYGIEVHRDKVYIFMEYCSGGSLAGLLEHG 1127
                   56789***********999....89999****996544443234489999*****************************************99987 PP

                   CTTTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEETTEEEE-STTTHEETTTSSEEEETT CS
  Pkinase_Tyr   96 ekekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsenkvvkisDfGLardiekddeyvkke 163 
                     +  + + ++ +alq+ +G++yL++  ++Hrd+   N+Ll++n v+k  DfG a+ i ++ ++ +++
   EEA20422.1 1128 --RVEDETFIMVYALQLLEGLAYLHQAGIIHRDIKPENILLDHNGVIKYVDFGAAKIIARQGKTIANT 1193
                   ..55566668889*******************************************998877776655 PP

  == domain 2  score: 32.9 bits;  conditional E-value: 1.9e-11
                   EEEETTSSTSGGGGS-HHHHHHSE.....EEHHHHHHHHHHHHHHHHTTSSGTTTTSHHH.HHHHHHHTTEE..S-BBTTSBHHHHHHHHHHT-SS CS
  Pkinase_Tyr  158 eyvkkeeaklpvkWmapEslkekk.....ftsksDvWsfGvllwEiftlgespypglkne.evleklkegkr..lekpekcpeelyelmkkcweed 245 
                   + +++++ +    +m+pE+++  +      + + D+Ws G ++ E++t g++p+++l+ne  ++ ++ +g++  l++ e+ ++   +++++c+e+d
   EEA20422.1 1215 QRKNQKTMTGTPMYMSPEVIRGDTseladRQGAIDIWSLGCVILEMAT-GRRPWSSLDNEwAIMYNIAQGNQpqLPTREQLSDLGIDFLSRCFERD 1309
                   4445555566678*******99887776667789**************.********6662566777887763367777888888999******** PP

                   GGGS--HHHHHH CS
  Pkinase_Tyr  246 peeRptfselve 257 
                   p +Rpt +el++
   EEA20422.1 1310 PMKRPTAAELLQ 1321
                   ******999976 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.5   2.6e-06    0.0052     151     199 ..    1140    1191 ..    1130    1304 .. 0.72

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 2.6e-06
  Kinase-like  151 lqlirlaanLqakglvhgkftvdnllldekgglmlggfta...Lvragtkvv 199 
                   lql+   a+L++ g++h +++++n+lld++g ++  +f+a   + r+g+   
   EEA20422.1 1140 LQLLEGLAYLHQAGIIHRDIKPENILLDHNGVIKYVDFGAakiIARQGKTIA 1191
                   7888889***************************999987333455555544 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0     2e-06     0.004     316     388 ..    1143    1236 ..    1130    1244 .. 0.65

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 2e-06
  Pkinase_fungal  316 IkghrsLflkagiLHrDiSenNilit...........dskke...gerkglLiDLDlakelsddsses...........garertGTleFmai 383 
                      ++g+  L+ +agi+HrDi  +Nil+                    +++   ++  +  ++    s+++           ++++ tGT+ +m+ 
      EEA20422.1 1143 LEGLAYLH-QAGIIHRDIKPENILLDhngvikyvdfgA---AkiiARQGKTIANTEAFTNAVGGSHKEglggakepqrkNQKTMTGTPMYMSP 1231
                      67889999.****************9444444443321...0333444444444444444444344444444444433333679********9 PP

  Pkinase_fungal  384 evlkg 388 
                      ev++g
      EEA20422.1 1232 EVIRG 1236
                      99986 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   2.7e-06    0.0054     155     197 ..    1142    1181 ..    1083    1185 .. 0.73

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 2.7e-06
                  HHHHH--S...SS-EEEE-SS-SGGGEEEC..TTEEEEE---TT-E CS
         APH  155 alaallpg...elptvllHgDlhpgNllvdpddgrvtGviDfedag 197 
                   l+    g     +++++H+D++p N+l+d ++g ++  +Df+ a+
  EEA20422.1 1142 LLE----GlayLHQAGIIHRDIKPENILLD-HNGVIK-YVDFGAAK 1181
                  333....2333679****************.666664.56888776 PP

>> Seadorna_VP7  Seadornavirus VP7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.0   7.3e-06     0.015     151     189 ..    1143    1179 ..    1128    1204 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 7.3e-06
  Seadorna_VP7  151 lkdLmdfhsestnllhGDcnpenlmcDknGylklvDPvs 189 
                    l+ L  +h  + +++h D++pen++ D+nG++k vD ++
    EEA20422.1 1143 LEGLAYLH--QAGIIHRDIKPENILLDHNGVIKYVDFGA 1179
                    56677778..899***********************653 PP

>> FtsX_ECD  FtsX extracellular domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   0.00015      0.29      58      96 .]    1051    1089 ..    1041    1089 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00015
    FtsX_ECD   58 gltedeNpLpdsfevklkdpekleevaeelkklpgVeeV 96  
                  +++ d+N L ++ e++l+dp+ ++++a+++++  gV eV
  EEA20422.1 1051 AINLDSNFLMAVKEIRLQDPQLIPVIAQQIRDEMGVLEV 1089
                  567899*****************************9887 PP

>> FERM_f0  N-terminal or F0 domain of Talin-head FERM
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.1   0.00013      0.25       9      43 ..     802     836 ..     798     861 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00013
     FERM_f0   9 eknvtktiqFdpettVydacklirekiaeaelgna 43 
                 e n +k+i F+ ++t+ d +++ir++++e+ ++n+
  EEA20422.1 802 ELNKIKKISFKLSMTIMDSVAVIRQQLREKGIENT 836
                 67889************************997764 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   0.1       4.4   8.7e+03       3      21 ..     244     262 ..     243     264 .. 0.87
   2 ?   10.0   0.0    0.0002       0.4     132     166 ..    1147    1177 ..    1140    1192 .. 0.82

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 4.4
         Kdo   3 vwakqgkvveeaegRrttw 21 
                 v++++++ +++ e+Rr+++
  EEA20422.1 244 VKQEKQRLIGSTETRRSAA 262
                 689999*********9875 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.0002
         Kdo  132 aklhragvnHadlyaknillqqeeeeeaeiwliDl 166 
                  a lh+ag+ H+d+ + nill+ ++     i  +D+
  EEA20422.1 1147 AYLHQAGIIHRDIKPENILLDHNG----VIKYVDF 1177
                  579******************998....5555565 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1370 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       411  (0.0229238); expected 358.6 (0.02)
Passed bias filter:                      338  (0.0188521); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.87u 0.34s 00:00:01.21 Elapsed: 00:00:00.53
# Mc/sec: 7788.12
//
Query:       EEA20423.1  [L=504]
Description: sphingosine kinase (SphK), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.6e-26   90.2   0.0    1.3e-25   89.5   0.0    1.4  1  DAGK_cat  Diacylglycerol kinase catalytic domain


Domain annotation for each model (and alignments):
>> DAGK_cat  Diacylglycerol kinase catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.5   0.0     7e-30   1.3e-25       2     125 ..     139     268 ..     138     269 .. 0.93

  Alignments for each domain:
  == domain 1  score: 89.5 bits;  conditional E-value: 7e-30
                 EEEEE-TTCTTTTHHHHH.HHCHHHHHHCTCEEEEEE--STTHHHHHHHHHHHCC-SEEEEEESHHHHHHHHHHHCT.....HHCTTSEEEEEE-SS-- CS
    DAGK_cat   2 llvivNpksGkgkgekll.rkvrelleeagvelelieteepgdakelakeakeegvdlivvaGGDGtvsevlnglle.....elatkpplgiiPlGtgN 94 
                 l v++Np++Gkg +++l+ + +++++e ag++++l  t+++g+a+++a++++ + +d+i++++GDG+  evlng+++     e+  k+++++iP+G+gN
  EEA20423.1 139 LRVLINPHGGKGYAKDLYnEYAAPMFEAAGCKVDLEMTKYAGHATDIAEKMDIDAYDAILCCSGDGLPYEVLNGFAKrsnaaEALAKVAVAMIPCGSGN 237
                 78****************99999******************************************************9988888888************ PP

                 HHHHHCT--SSHHHHHHCHHCTBEEEEEEEE CS
    DAGK_cat  95 dlaralgigkdieealesiikgetrkvdvgk 125
                 ++a++l   +++  ++ s+ikg ++++d+++
  EEA20423.1 238 AMAWNLFGTNSVSLSALSVIKGLRTHMDLVS 268
                 ******55558888999999********986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (504 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       454  (0.0253221); expected 358.6 (0.02)
Passed bias filter:                      441  (0.024597); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 3429.23
//
Query:       EEA20424.1  [L=956]
Description: Coatomer subunit beta, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.4e-99  333.3   9.9    3.9e-99  332.6   9.9    1.3  1  Adaptin_N        Adaptin N terminal region
    8.5e-58  194.2   0.3    2.2e-57  192.9   0.3    1.8  1  Coatamer_beta_C  Coatomer beta C-terminal region
    1.2e-56  190.2   0.0    3.4e-56  188.7   0.0    1.8  1  Coatomer_b_Cpla  Coatomer beta subunit appendage platform
    4.6e-15   56.0   7.5    4.1e-11   43.2   0.1    3.0  3  Cnd1             non-SMC mitotic condensation complex subunit
    1.2e-10   41.6   2.3      5e-06   26.8   0.0    4.6  4  HEAT_2           HEAT repeats
    8.5e-05   23.0   0.2      0.074   13.6   0.0    4.6  4  HEAT_EZ          HEAT-like repeat
    9.4e-05   22.5   0.0    0.00045   20.3   0.0    2.2  2  Coatomer_g_Cpla  Coatomer subunit gamma-1 C-terminal appendag
    0.00025   21.0   0.6       0.33   11.3   0.0    4.7  5  HEAT             HEAT repeat
    0.00033   19.6   3.4      0.027   13.3   0.0    2.8  3  API5             Apoptosis inhibitory protein 5 (API5)
  ------ inclusion threshold ------
      0.015   15.6   0.3      0.057   13.8   0.3    2.0  1  AP4E_app_platf   Adaptin AP4 complex epsilon appendage platfo
      0.021   14.2   1.7        2.6    7.4   0.0    2.8  2  DUF5578          Family of unknown function (DUF5578)
      0.089   12.9   4.1        1.1    9.3   0.0    4.6  5  Arm              Armadillo/beta-catenin-like repeat


Domain annotation for each model (and alignments):
>> Adaptin_N  Adaptin N terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  332.6   9.9  2.6e-102   3.9e-99       4     469 ..      21     490 ..      18     496 .. 0.96

  Alignments for each domain:
  == domain 1  score: 332.6 bits;  conditional E-value: 2.6e-102
                 HCCHHHHHHCCSSS-SCHHHHHHHHHHHHHHHCT---GHHHHHHHCCCC.SS-CHHHHHHHHHHHHHCTTSCC.....HHCCCCHHHHHHCCSSSHHHH CS
   Adaptin_N   4 riqqelaeilnsnkdddekkkeavkkliylialGedvsflffevvklva.skdfelKrlvYlylellaeesed.....lalLvtnslqkDlkdpnqlir 96 
                  + qel+  l++    de+k e+++++i ++++G+++  l+++++++v+ sk+  lK+l+Y+y e++++ + +     +++Lv+n +++Dl++pn++ir
  EEA20424.1  21 PSLQELKMQLEKG--TDETKQETMRRIITIMLNGDPMAGLLMHIIRFVMpSKNKPLKKLLYFYYEICPKHDANgklkqEMILVCNGIRNDLQHPNEYIR 117
                 5679999999999..*********************************************************999999********************* PP

                 HHHHHHHCCC--CCCHHHHHHHHHHHHT-SSHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHCT..T-SSHHHHHHHHHHHHHHHCCCCCCCHHHHHH CS
   Adaptin_N  97 glALrvLssirvpelaedlapaikkllkdrspyvrkkAalailklykkdpdllrkqlveeikell..sdkdpgvvlaAvalleeikkndrlllkllpkl 193
                 g++Lr+L+++r+pel e l+   +++l++r++yvrk+A+ ai  +y+ +++l+++  ++e+ + +  s++d+ ++++A+a+l +i    +   k+l++l
  EEA20424.1 118 GNTLRFLCKLREPELIEPLLSSARSCLEHRHAYVRKNAVWAISSIYQHSESLIPD--APELLQTFleSESDHTCKRNAFAALMSI---SHQ--KALEYL 209
                 *****************************************************99..56666666588889**************...666..789999 PP

                 HCCHHHHHHCS-HHHHHHHHHHHCC---SSHHHH..HHHHHHHCGGCGCSSCHHHHHHHHHCCHCCCCSTHHHCCHHCHHHHHH.SSCCTCHHHHHCHH CS
   Adaptin_N 194 vrrLcnllteldpwlqvkiiklltrlarqepeerskkellesllnllqssnnaVlletvnlivelapknelivlavnaLvrlls.skdenlryvaLrtl 291
                 ++ ++ +  + d++lq+  ++++++ a q+ + +  +++l+ +  ll  s+ +V++e++  ++ l +++ ++++a+++L++l   + d+n+++++L++ 
  EEA20424.1 210 SSTFDSI-PNADELLQLAELEFIRKDAVQNAQNK--ARYLRLIFDLLDASASTVIYEAATSLTALTSNPVAVKAAASKLIELSIkEADNNVKLIVLDRV 305
                 9999988.9*************************..78********************************************7779************* PP

                 HHHHHHXXTTTTTTTCCCCSXXTTSXHHHHHHHHHHHCCCXXTTTHHHHHHHHHHHTTSSXXHH......HHHHHHHHHHHHHHHSCCHHHHHHHHHHH CS
   Adaptin_N 292 lkivkkepkavqhldlkifllktdddvsirlkaldlllklvdesNvkeivkeLkkyvkevaded......fksklvkaIgrlaekfatdaewvldvlle 384
                  ++ ++++  +++l+++i ++ +++d+++r+kal + +++v+++Nv+eiv  Lkk+++++ de+      +++ l+++I+++a+kf + a++v+d l++
  EEA20424.1 306 DQLRMRNEGVLEDLTMEILRVLSSPDIDVRRKALGIAMEMVSSKNVEEIVMLLKKELAKTVDEQyeksseYRQLLIQSIHHCAIKFSEIAASVVDLLMD 404
                 *******77777*********************************************88889989999******************************* PP

                 HHTTXXHHHHHHHHHHHHHHHHHSTTTSTTCHHHHCCTCCGXXSHHHHHHHHHHHHHTTTTXTT....HHHHHHCTTTTTTTSXHH CS
   Adaptin_N 385 llslsgesvkdeivevirdliqkvpelheeiiekLaellekieseearaaaiWllGeygelvsnte.sasdllrslaekfvlesek 469
                 ++ + ++  + +++++++++++k+p+l+++iie+L+++l++++  +++++++W++Gey+ ++s+++  ++++  sl e ++l+se+
  EEA20424.1 405 FIGDFNNNSAVDVISFVKEVVEKFPKLRGSIIERLVATLSEVRAGKVYRGVLWVIGEYSLETSDIReAWKRIRASLGEIPILASEQ 490
                 ****************************************************************999*************999986 PP

>> Coatamer_beta_C  Coatomer beta C-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  192.9   0.3   1.5e-60   2.2e-57       1     139 [.     680     815 ..     680     816 .. 0.97

  Alignments for each domain:
  == domain 1  score: 192.9 bits;  conditional E-value: 1.5e-60
  Coatamer_beta_C   1 vddlisfrqlkekkelseeeeedlveedlsqatgakkkeeefasklkkvvqLtGfsDpvYaEayvkvnqfDivLdvlivNqtketLqnltvela 94 
                      +dd+i +rql++k++ +     d++e dl +atg++++ e+++skl+++vqLtGfsDpvYaEayv+v+qfDi+Ldvl+vNqt+etLqnl+ve+a
       EEA20424.1 680 IDDAIPIRQLTKKNAGEGA---DEIELDLIKATGGDSTVEDLSSKLSRIVQLTGFSDPVYAEAYVQVHQFDIILDVLLVNQTTETLQNLSVEFA 770
                      69**********9966665...569********************************************************************* PP

  Coatamer_beta_C  95 tlgdlklvekpqsvtlaphdfakikatvkvsstetGvifGnivYd 139
                      tlgdlk+ve+p++ +l+p+df +++atvkvsst++GvifGn+vY+
       EEA20424.1 771 TLGDLKVVERPTTQNLGPRDFLNVQATVKVSSTDAGVIFGNVVYE 815
                      ********************************************8 PP

>> Coatomer_b_Cpla  Coatomer beta subunit appendage platform
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  188.7   0.0   2.3e-59   3.4e-56       2     126 ..     822     947 ..     821     948 .. 0.98

  Alignments for each domain:
  == domain 1  score: 188.7 bits;  conditional E-value: 2.3e-59
  Coatomer_b_Cpla   2 rnvvilndikidimdyikpakiseeeFremWaefeWEnkiavktkltdlkeyleelvkktnmklltpeeeleeeaeflsanlyaksvfgedala 95 
                      ++vvilndi+ dimdyi+pa+++e++Fr+mW+efeWEnk+++++k +dl+e+l++l+++tnm++ltpe++l+++++flsanlya+svfgedala
       EEA20424.1 822 THVVILNDIHADIMDYIQPAHCTETQFRTMWTEFEWENKVNINSKAKDLREFLKQLMESTNMTCLTPEASLQGDCQFLSANLYARSVFGEDALA 915
                      689******************************************************************************************* PP

  Coatomer_b_Cpla  96 nvsiekee.egkisgvvRiRsktqgialslgd 126
                      n+sieke+ +g i+g+vRiRs++qg+al+lg+
       EEA20424.1 916 NLSIEKEGeDGPITGFVRIRSRSQGLALALGN 947
                      *******989********************96 PP

>> Cnd1  non-SMC mitotic condensation complex subunit 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.2   0.1   2.8e-14   4.1e-11       2     105 ..     116     220 ..     115     283 .. 0.85
   2 !   15.8   1.0   7.2e-06     0.011      14     157 ..     311     455 ..     299     459 .. 0.92
   3 ?   -2.6   0.1       3.4   5.1e+03      74     106 ..     626     659 ..     589     678 .. 0.58

  Alignments for each domain:
  == domain 1  score: 43.2 bits;  conditional E-value: 2.8e-14
        Cnd1   2 iRalairtlgcirvpnlveylvepLrkrLkDedpyVRktaaivvakLilndmvkekgflselakll.eDenprVvanalaalteiseksenaiynllpd 99 
                 iR++ +r l+ +r p+l+e+l++  r++L+ +++yVRk+a+ +++ ++++      +  + l++ l ++++++   na aal+ is+++  + ++++ d
  EEA20424.1 116 IRGNTLRFLCKLREPELIEPLLSSARSCLEHRHAYVRKNAVWAISSIYQHSESLIPDAPELLQTFLeSESDHTCKRNAFAALMSISHQKALEYLSSTFD 214
                 9**********************************************99998888889999***9*88999*****************87777777766 PP

        Cnd1 100 iiskls 105
                 +i +  
  EEA20424.1 215 SIPNAD 220
                 665554 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 7.2e-06
        Cnd1  14 rvpnlveylvepLrkrLkDedpyVRktaaivvakLilndmvkekg..flselaklleDenprVvanalaalteiseksenaiynllpdiisklsdalne 110
                 r + ++e l+ ++ + L+ +d  VR+ a+ +  ++++ + v+e    + +elak ++++ ++ ++  +++++ i++ +  ++ ++  +++  l d + +
  EEA20424.1 311 RNEGVLEDLTMEILRVLSSPDIDVRRKALGIAMEMVSSKNVEEIVmlLKKELAKTVDEQYEKSSEYRQLLIQSIHHCA-IKFSEIAASVVDLLMDFIGD 408
                 6677999****************************9999998877557789**************************8.789999999999999999** PP

        Cnd1 111 csewgqitilefLlsyipkdkqeaeslveklcprlqhansavvlaai 157
                 +++++ + +++f+ + ++k  +   s++e+l++ l+ ++  +v + +
  EEA20424.1 409 FNNNSAVDVISFVKEVVEKFPKLRGSIIERLVATLSEVRAGKVYRGV 455
                 **********************9*************99999887755 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 3.4
        Cnd1  74 Vvanalaalteisekse..naiynllpdiisklsd 106
                 ++  ++ +l+e se++e  +++++ +++ ++ +++
  EEA20424.1 626 IM-TCVRSLSEFSERKEleTTFLEDTRKAFKTIVQ 659
                 43.35666777777743224444444455555444 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.0   3.3e-09     5e-06       8      87 ..     109     197 ..     104     198 .. 0.86
   2 ?    5.4   0.0     0.016        23       4      37 ..     177     210 ..     173     220 .. 0.70
   3 !    6.3   0.4    0.0085        13      28      80 ..     241     298 ..     219     303 .. 0.79
   4 !    6.5   0.1    0.0071        11       3      74 ..     284     361 ..     282     373 .. 0.75

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 3.3e-09
      HEAT_2   8 lendpdpevrraairaLgrignpealpaLvell....ededpavRraaaeaLgaigd......pealpaLkellddddddvvReaAaeaL 87 
                 l ++p++++r +++r L ++++pe+++ L++ +    e+ +++vR++a++a++ i        p+a ++L+  l +++d   ++ A  aL
  EEA20424.1 109 L-QHPNEYIRGNTLRFLCKLREPELIEPLLSSArsclEHRHAYVRKNAVWAISSIYQhsesliPDAPELLQTFLESESDHTCKRNAFAAL 197
                 5.79*********************999998875333567799**********996323457899*******************999887 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.016
      HEAT_2   4 LlqalendpdpevrraairaLgrignpealpaLv 37 
                 L  +le+ +d+  +r+a  aL +i +++al++L 
  EEA20424.1 177 LQTFLESESDHTCKRNAFAALMSISHQKALEYLS 210
                 3446677777777888888888888888887775 PP

  == domain 3  score: 6.3 bits;  conditional E-value: 0.0085
      HEAT_2  28 gnpealpaLvellededpavRraaaeaLgaigd.....pealpaLkellddddddvvR 80 
                 +  ++l+++++ll+ + + v ++aa++L a+ +     ++a++ L el   + d  v+
  EEA20424.1 241 NKARYLRLIFDLLDASASTVIYEAATSLTALTSnpvavKAAASKLIELSIKEADNNVK 298
                 345789************************9744444488999999999988887776 PP

  == domain 4  score: 6.5 bits;  conditional E-value: 0.0071
      HEAT_2   3 aLlqalendpdpevrraairaLg..rignp....ealpaLvellededpavRraaaeaLgaigdpealpaLkellddd 74 
                 +L+++  + +d +v+  +++     r++n+    ++   ++++l+++d +vRr a   + ++ ++++++   +ll+ +
  EEA20424.1 284 KLIELSIKEADNNVKLIVLDRVDqlRMRNEgvleDLTMEILRVLSSPDIDVRRKALGIAMEMVSSKNVEEIVMLLKKE 361
                 57777778888888888888888555666666667788899999***********98888887777777777766655 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.0   0.0   7.6e-05      0.11      25      55 .]     128     162 ..     124     162 .. 0.89
   2 !   13.6   0.0   4.9e-05     0.074       2      52 ..     150     197 ..     149     199 .. 0.89
   3 ?   -2.7   0.0       6.2   9.3e+03      32      49 ..     270     283 ..     261     287 .. 0.71
   4 ?    1.3   0.0      0.36   5.3e+02      22      50 ..     316     340 ..     310     341 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 7.6e-05
     HEAT_EZ  25 lvpeilpaLl....alLnddsdeVRaaAagaLgnl 55 
                   pe++ +Ll    ++L++ ++ VR++A++a++ +
  EEA20424.1 128 REPELIEPLLssarSCLEHRHAYVRKNAVWAISSI 162
                 579999999999999*****************986 PP

  == domain 2  score: 13.6 bits;  conditional E-value: 4.9e-05
     HEAT_EZ   2 rvRraAawaLGrlaggepellqplvpeilpaLlalLnddsdeV.RaaAagaL 52 
                  vR +A+wa++++     ++ + l+p++  +L  +L+++sd++ + +A  aL
  EEA20424.1 150 YVRKNAVWAISSIY----QHSESLIPDAPELLQTFLESESDHTcKRNAFAAL 197
                 59********8877....79999999****************9998888776 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 6.2
     HEAT_EZ  32 aLlalLnddsd.eVRaaAa 49 
                 aL      +++ +V+aaA 
  EEA20424.1 270 ALT-----SNPvAVKAAAS 283
                 444.....66769999986 PP

  == domain 4  score: 1.3 bits;  conditional E-value: 0.36
     HEAT_EZ  22 lqplvpeilpaLlalLnddsd.eVRaaAag 50 
                 l++l  eil+ L      ++d +VR +A+g
  EEA20424.1 316 LEDLTMEILRVLS-----SPDiDVRRKALG 340
                 5556666777777.....7777****9987 PP

>> Coatomer_g_Cpla  Coatomer subunit gamma-1 C-terminal appendage platform
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       3.8   5.7e+03      27      54 ..     460     486 ..     458     491 .. 0.79
   2 !   20.3   0.0     3e-07   0.00045       2     109 ..     836     943 ..     835     948 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 3.8
                      EEEEESS---HHHHHHHHHHHHT-EE-T CS
  Coatomer_g_Cpla  27 etfaLssvksleeavdkliellgmqple 54 
                       +++L + ++++ea +++  +lg  p+ 
       EEA20424.1 460 GEYSL-ETSDIREAWKRIRASLGEIPIL 486
                      57899.7799999999999999976665 PP

  == domain 2  score: 20.3 bits;  conditional E-value: 3e-07
                      GGEEE---S..-HHHHHHHH-STT-EEEEEEE.SS---HHHHHHHHHHHHT-EE-TTTT---SS-SEEEEEEEEEETTS-EEEEEEEEEE...S CS
  Coatomer_g_Cpla   2 Dyikpvavs..nFeaaWeeleseaeavetfaL.ssvksleeavdkliellgmqplegsdkvpenassHtLklaGkfvggekvlvrarlalss.s 91 
                      Dyi+p++ +  +F+++W e e     ++++++ s+ k+l+e  ++l+e+++m  l      + + +  + +l+  +v ge+ l+++++ ++  +
       EEA20424.1 836 DYIQPAHCTetQFRTMWTEFEW----ENKVNInSKAKDLREFLKQLMESTNMTCLTPEASLQGDCQFLSANLYARSVFGEDALANLSIEKEGeD 925
                      9*****99989*******9888....4667777799*******************999999999999***********************9978 PP

                      S.EEEEEEEEESSHHHHH CS
  Coatomer_g_Cpla  92 kgvtlkltvRsedeevae 109
                      + +t  + +Rs ++ +a 
       EEA20424.1 926 GPITGFVRIRSRSQGLAL 943
                      88*********9998875 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0       2.5   3.7e+03       9      26 ..     109     126 ..     103     127 .. 0.82
   2 !   11.3   0.0   0.00022      0.33       7      30 ..     142     165 ..     136     166 .. 0.87
   3 ?   -2.8   0.0       7.8   1.2e+04       5      27 ..     177     200 ..     175     201 .. 0.63
   4 ?    0.1   0.0      0.89   1.3e+03       3      29 ..     247     273 ..     246     274 .. 0.87
   5 ?    2.8   0.0      0.12   1.8e+02       5      21 ..     323     339 ..     321     345 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 2.5
                 HT-SSHHHHHHHHHHHHH CS
        HEAT   9 lsDpspeVReaAakaLga 26 
                 l++p+  +R ++++ L++
  EEA20424.1 109 LQHPNEYIRGNTLRFLCK 126
                 899******999998876 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00022
                 HHHT-SSHHHHHHHHHHHHHHHHC CS
        HEAT   7 kllsDpspeVReaAakaLgalaev 30 
                 ++l++ ++ VR++A++a+  ++++
  EEA20424.1 142 SCLEHRHAYVRKNAVWAISSIYQH 165
                 6899*****************987 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 7.8
                 HHHHHT-SSHHH.HHHHHHHHHHH CS
        HEAT   5 llkllsDpspeV.ReaAakaLgal 27 
                 l++ l+++s +   ++A+ aL  +
  EEA20424.1 177 LQTFLESESDHTcKRNAFAALMSI 200
                 566676665553378888888766 PP

  == domain 4  score: 0.1 bits;  conditional E-value: 0.89
                 HHHHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   3 PlllkllsDpspeVReaAakaLgalae 29 
                  l+  ll  +++ V + Aa +L+al +
  EEA20424.1 247 RLIFDLLDASASTVIYEAATSLTALTS 273
                 6788999999999**********9987 PP

  == domain 5  score: 2.8 bits;  conditional E-value: 0.12
                 HHHHHT-SSHHHHHHHH CS
        HEAT   5 llkllsDpspeVReaAa 21 
                 +l+ ls+p+ +VR+ A+
  EEA20424.1 323 ILRVLSSPDIDVRRKAL 339
                 57789********9996 PP

>> API5  Apoptosis inhibitory protein 5 (API5)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.3   0.0   1.8e-05     0.027      66     156 ..     142     233 ..     128     244 .. 0.87
   2 ?   -1.7   0.1      0.62   9.3e+02      35      70 ..     373     408 ..     332     438 .. 0.57
   3 !    6.0   0.1     0.003       4.5     229     262 ..     616     649 ..     589     683 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.8e-05
        API5  66 DLiedddlgirkqAikdLpslckdtkeyvskiadiLaQlLite.daveldavhkallsllkldakasltalfkqieteeetvRekvlkfire 156
                  ++e     +rk A+ ++ s+ + +++ ++   + L   L +e d + +     al+s+ ++ a + l++ f++i + +e +    l+fir+
  EEA20424.1 142 SCLEHRHAYVRKNAVWAISSIYQHSESLIPDAPELLQTFLESEsDHTCKRNAFAALMSISHQKALEYLSSTFDSIPNADELLQLAELEFIRK 233
                 677889999*******************************99834555667889***********************************987 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.62
        API5  35 sakeKrLasqlipkFfkfFPslaekaidaqlDLied 70 
                 s++ ++L  q i   +  F ++a +++d ++D i d
  EEA20424.1 373 SSEYRQLLIQSIHHCAIKFSEIAASVVDLLMDFIGD 408
                 333344444444444444444444444444444443 PP

  == domain 3  score: 6.0 bits;  conditional E-value: 0.003
        API5 229 nvsdkdhvdrlisclkkalpffskgvssskflny 262
                  + d+d+vdr+++c++  + f +++   + fl+ 
  EEA20424.1 616 APIDEDSVDRIMTCVRSLSEFSERKELETTFLED 649
                 5679*********************999999975 PP

>> AP4E_app_platf  Adaptin AP4 complex epsilon appendage platform
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.3   3.8e-05     0.057       1      46 [.     840     885 ..     840     891 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 3.8e-05
  AP4E_app_platf   1 PltisteeFgklWlslsserkqklkssqvstlselkalleklslhv 46 
                     P++ +  +F ++W +++ e k++++s+++ + + lk+l+e+ ++ +
      EEA20424.1 840 PAHCTETQFRTMWTEFEWENKVNINSKAKDLREFLKQLMESTNMTC 885
                     7889999******************7777666667***99988765 PP

>> DUF5578  Family of unknown function (DUF5578)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.5      0.01        15     154     256 ..     251     353 ..     243     365 .. 0.76
   2 ?    7.4   0.0    0.0017       2.6     198     267 ..     373     444 ..     368     445 .. 0.92

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.01
     DUF5578 154 eclakskseetqeeaqklleslaegnPkyqkqvykgliallacsspkaqqlal.qtlrvvqeivkeakpsivepllelLkslhlevqyeaielikelms 251
                 ++l  s s    e+a +l     ++nP   k   + li l   ++ +  +l + + +  ++ + + +   +   +l +L+s +++v+ +a+ +  e++s
  EEA20424.1 251 DLLDASASTVIYEAATSLT--ALTSNPVAVKAAASKLIELSIKEADNNVKLIVlDRVDQLRMRNEGVLEDLTMEILRVLSSPDIDVRRKALGIAMEMVS 347
                 5666677777776666653..34679999999999999999888877766654499999999999999*********************9999888775 PP

     DUF5578 252 t.evra 256
                 + +v++
  EEA20424.1 348 SkNVEE 353
                 513333 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0017
     DUF5578 198 spkaqqlalqtlrvvqeivkeakpsivepllelLkslhlevqyeaielikelmst..evraallkglvalLk 267
                 s + +ql +q+++    + +e   s+v+ l++ +   + +   ++i+++ke++++  ++r +++++lva L+
  EEA20424.1 373 SSEYRQLLIQSIHHCAIKFSEIAASVVDLLMDFIGDFNNNSAVDVISFVKEVVEKfpKLRGSIIERLVATLS 444
                 66779***********************************************976679*********99875 PP

>> Arm  Armadillo/beta-catenin-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.0   0.00077       1.1      19      39 ..     142     162 ..     132     162 .. 0.91
   2 ?   -2.6   0.2       4.4   6.6e+03      19      37 ..     251     269 ..     251     273 .. 0.82
   3 ?    0.8   0.0      0.37   5.6e+02      18      34 ..     324     340 ..     323     341 .. 0.88
   4 ?   -2.0   0.0       2.9   4.3e+03      15      37 ..     553     575 ..     553     578 .. 0.77
   5 ?   -2.3   0.0       3.5   5.2e+03      29      40 ..     755     766 ..     751     767 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00077
                 HHTTTSSHHHHHHHHHHHHHH CS
         Arm  19 rLLssedeevqeeAawALsNL 39 
                 ++L++ +  v+++A+wA+s +
  EEA20424.1 142 SCLEHRHAYVRKNAVWAISSI 162
                 6899**************975 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 4.4
                 HHTTTSSHHHHHHHHHHHH CS
         Arm  19 rLLssedeevqeeAawALs 37 
                 +LL+    +v  eAa+ L+
  EEA20424.1 251 DLLDASASTVIYEAATSLT 269
                 5899999999999*99887 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.37
                 HHHTTTSSHHHHHHHHH CS
         Arm  18 vrLLssedeevqeeAaw 34 
                 +r Lss+d +v++ A++
  EEA20424.1 324 LRVLSSPDIDVRRKALG 340
                 6789*********9986 PP

  == domain 4  score: -2.0 bits;  conditional E-value: 2.9
                 HHHHHHTTTSSHHHHHHHHHHHH CS
         Arm  15 ppLvrLLssedeevqeeAawALs 37 
                 ppL +L+ ++d  + ++  ++L+
  EEA20424.1 553 PPLRQLILDGDYYLATVLSSTLT 575
                 89*****9999877777666665 PP

  == domain 5  score: -2.3 bits;  conditional E-value: 3.5
                 HHHHHHHHHHHT CS
         Arm  29 qeeAawALsNLa 40 
                 + + + +L+NL+
  EEA20424.1 755 VNQTTETLQNLS 766
                 678899*****8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (956 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1119  (0.0624129); expected 358.6 (0.02)
Passed bias filter:                      584  (0.0325729); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.87u 0.32s 00:00:01.19 Elapsed: 00:00:00.52
# Mc/sec: 5554.36
//
Query:       EEA20425.1  [L=164]
Description: Mago nashi domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.8e-70  235.6   0.1    2.1e-70  235.4   0.1    1.0  1  Mago_nashi  Mago nashi protein


Domain annotation for each model (and alignments):
>> Mago_nashi  Mago nashi protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  235.4   0.1   1.2e-74   2.1e-70       1     141 [.       8     153 ..       8     154 .. 0.96

  Alignments for each domain:
  == domain 1  score: 235.4 bits;  conditional E-value: 1.2e-74
  Mago_nashi   1 fylryyvghkgkfGheflefefksdg.....klryannsnYkndslirkevlvskavlkelkriieeseilkeddakwpkkdkvgkqeleiklgkehis 94 
                 fylryy+gh+g+fGheflef+f++ g     + ryannsnY+ndslirke++vs+++++e+krii++sei+kedd+kwp+k+k+g+qelei+lg+ehi 
  EEA20425.1   8 FYLRYYSGHSGRFGHEFLEFDFRTLGdgrsaSARYANNSNYRNDSLIRKEMCVSSLLIAEIKRIIKDSEIMKEDDSKWPQKNKDGRQELEIRLGTEHIL 106
                 9*********************97654455579****************************************************************** PP

  Mago_nashi  95 fetakigslvdvqesedpeGlrvfyylvqDlkalvfslislhfkikP 141
                 fetakigslvdv+es dpeGlrvfyylvqDlkalvfslislhfk+ P
  EEA20425.1 107 FETAKIGSLVDVTESADPEGLRVFYYLVQDLKALVFSLISLHFKVLP 153
                 ********************************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (164 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       434  (0.0242066); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.48
# Mc/sec: 1023.48
//
Query:       EEA20426.1  [L=154]
Description: Mago nashi domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.9e-72  242.0   0.1    2.1e-72  241.8   0.1    1.0  1  Mago_nashi  Mago nashi protein


Domain annotation for each model (and alignments):
>> Mago_nashi  Mago nashi protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  241.8   0.1   1.2e-76   2.1e-72       1     142 []       8     154 .]       8     154 .] 0.97

  Alignments for each domain:
  == domain 1  score: 241.8 bits;  conditional E-value: 1.2e-76
  Mago_nashi   1 fylryyvghkgkfGheflefefksdg.....klryannsnYkndslirkevlvskavlkelkriieeseilkeddakwpkkdkvgkqeleiklgkehis 94 
                 fylryy+gh+g+fGheflef+f++ g     + ryannsnY+ndslirke++vs+++++e+krii++sei+kedd+kwp+k+k+g+qelei+lg+ehi 
  EEA20426.1   8 FYLRYYSGHSGRFGHEFLEFDFRTLGdgrsaSARYANNSNYRNDSLIRKEMCVSSLLIAEIKRIIKDSEIMKEDDSKWPQKNKDGRQELEIRLGTEHIL 106
                 9*********************97654455579****************************************************************** PP

  Mago_nashi  95 fetakigslvdvqesedpeGlrvfyylvqDlkalvfslislhfkikPi 142
                 fetakigslvdv+es dpeGlrvfyylvqDlkalvfslislhfkikPi
  EEA20426.1 107 FETAKIGSLVDVTESADPEGLRVFYYLVQDLKALVFSLISLHFKIKPI 154
                 ***********************************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (154 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       377  (0.0210274); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.24s 00:00:00.63 Elapsed: 00:00:00.39
# Mc/sec: 1175.53
//
Query:       EEA20427.1  [L=136]
Description: Mago nashi domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    7.2e-45  152.6   0.2    8.7e-45  152.3   0.2    1.0  1  Mago_nashi  Mago nashi protein


Domain annotation for each model (and alignments):
>> Mago_nashi  Mago nashi protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  152.3   0.2   4.9e-49   8.7e-45       1     105 [.       8     117 ..       8     123 .. 0.94

  Alignments for each domain:
  == domain 1  score: 152.3 bits;  conditional E-value: 4.9e-49
  Mago_nashi   1 fylryyvghkgkfGheflefefksdg.....klryannsnYkndslirkevlvskavlkelkriieeseilkeddakwpkkdkvgkqeleiklgkehis 94 
                 fylryy+gh+g+fGheflef+f++ g     + ryannsnY+ndslirke++vs+++++e+krii++sei+kedd+kwp+k+k+g+qelei+lg+ehi 
  EEA20427.1   8 FYLRYYSGHSGRFGHEFLEFDFRTLGdgrsaSARYANNSNYRNDSLIRKEMCVSSLLIAEIKRIIKDSEIMKEDDSKWPQKNKDGRQELEIRLGTEHIL 106
                 9*********************97654455579****************************************************************** PP

  Mago_nashi  95 fetakigslvd 105
                 fe+ +++++ +
  EEA20427.1 107 FEVRRLTTIRE 117
                 *****999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (136 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       363  (0.0202465); expected 358.6 (0.02)
Passed bias filter:                      238  (0.0132746); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.28s 00:00:00.71 Elapsed: 00:00:00.45
# Mc/sec: 907.30
//
Query:       EEA20428.1  [L=330]
Description: vesicle-mediated transport protein Vid24, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-67  226.7   3.5    1.7e-67  226.3   3.5    1.2  1  Vac_ImportDeg  Vacuolar import and degradation protein


Domain annotation for each model (and alignments):
>> Vac_ImportDeg  Vacuolar import and degradation protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  226.3   3.5   9.4e-72   1.7e-67       1     161 [.     148     317 ..     148     318 .. 0.98

  Alignments for each domain:
  == domain 1  score: 226.3 bits;  conditional E-value: 9.4e-72
  Vac_ImportDeg   1 flrpgakfkGeqqsgkkkyevkvelktvdleeslltGfleikglteekpeittffegeiidekysfltkkkkwkaseetDlehWkkleafkkllak 96 
                    flr+g++f+G+q+s+++ y+v+ve+k+vd++es+l+G+l+i+gltee+p++ttffegeii +k++f+tk+++w+a+e+tD++hW+++ea+++l ++
     EEA20428.1 148 FLRAGSRFEGTQESDHQVYNVHVEIKHVDMAESYLCGYLRIQGLTEEHPTLTTFFEGEIIGTKHTFVTKNETWGANEKTDMQHWARFEAWRPLAKQ 243
                    799*****************************************************************************************9888 PP

  Vac_ImportDeg  97 .........dlenkelifmrwkekflvpdervksiegasfeGfYYivldqstgsieGlYyhkksekfqqLeLkp 161
                             +++++e++fmrwke flvpd+rv++i+gasfeGfYYi+++q +g+++G+Y+h+ksek+q+LeL++
     EEA20428.1 244 akradftyrNYAQREHLFMRWKEYFLVPDHRVRQISGASFEGFYYICFNQIEGTVSGIYFHAKSEKYQKLELNH 317
                    9*****999999************************************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (330 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1058  (0.0590105); expected 358.6 (0.02)
Passed bias filter:                      517  (0.028836); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.49
# Mc/sec: 2043.50
//
Query:       EEA20429.1  [L=338]
Description: ribosomal RNA processing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      8e-56  189.2   0.6    7.2e-40  137.1   0.2    2.1  2  Nop52       Nucleolar protein,Nop52
  ------ inclusion threshold ------
       0.15   12.1   0.0       0.15   12.1   0.0    1.8  2  NOT2_3_5    NOT2 / NOT3 / NOT5 family
       0.32    9.5   4.0       0.51    8.8   4.0    1.2  1  LRIF1       Ligand-dependent nuclear receptor-interacting fac
        1.8    9.1   9.6        1.2    9.6   2.4    2.3  2  Afi1        Docking domain of Afi1 for Arf3 in vesicle traffi
        1.8    7.7   6.4        6.4    5.9   0.9    2.1  2  TRAP_alpha  Translocon-associated protein (TRAP), alpha subun
        2.9    8.1  17.9          4    7.7   9.5    2.3  2  AP3D1       AP-3 complex subunit delta-1
        6.6    6.4   4.7       0.55   10.0   0.1    1.5  2  Connexin    Connexin


Domain annotation for each model (and alignments):
>> Nop52  Nucleolar protein,Nop52
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.1   0.2   2.8e-43   7.2e-40       2     124 ..      10     130 ..       9     150 .. 0.94
   2 !   50.6   0.0     8e-17     2e-13     129     215 ..     193     299 ..     179     300 .. 0.81

  Alignments for each domain:
  == domain 1  score: 137.1 bits;  conditional E-value: 2.8e-43
       Nop52   2 klakkLasndkktRdkalksLrkfLskkkkkklselellkLwkGLFycmWmsDkplvQqelaeeLa.elvkslkskeaalkFlkafwetmsreWkgiDk 99 
                 +++++Las+d+ktRdkal+sL+ fL+++k+  ls lellk+w+GLF+c+++sD+pl+Qq la+ L+ +lv sl+ +e+ l+Fl+afw t+  e++++D+
  EEA20429.1  10 PFVRELASSDRKTRDKALESLTLFLKARKD--LSLLELLKVWRGLFFCFYHSDRPLTQQALARALSfSLVPSLP-RESRLRFLRAFWITIGTEFHNLDR 105
                 8***************************95..9********************************978999999.7*********************** PP

       Nop52 100 lRlDKfllLvRrvlreslkllkkee 124
                 lRlDK+l+L+R+++  ++++  k +
  EEA20429.1 106 LRLDKYLFLIRCYVGVAFEIYLKGK 130
                 ******************9876655 PP

  == domain 2  score: 50.6 bits;  conditional E-value: 8e-17
       Nop52 129 lveeylevlketpl..........ssedkkvp...........nglayhladiyldelekvleseleeeeeeedee.....evplekllepfvkllkks 201
                  +e y+++l+e pl          +      p           +gl+yh+ di+ldelekv+ s ++++++ee        +vp+e ll+pf kl k+s
  EEA20429.1 193 ELESYISLLEEGPLcpinfdpkekK------PskdevamphgpDGLRYHISDIWLDELEKVVSSYDSDDQNEEVVPvkdrlDVPIELLLRPFEKLNKES 285
                 5688999999998855555333331......145566677888*****************999998888877655599999****************** PP

       Nop52 202 kskallkkikeevl 215
                 ++k+++ k+++evl
  EEA20429.1 286 QTKSVRMKVESEVL 299
                 ************98 PP

>> NOT2_3_5  NOT2 / NOT3 / NOT5 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   5.9e-05      0.15      53      74 ..      52      73 ..      35      75 .. 0.92
   2 ?   -3.7   0.6       4.6   1.2e+04      93     112 ..     318     337 ..     305     337 .. 0.47

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 5.9e-05
    NOT2_3_5 53 LFyiFYysqgtleqllAakeLk 74
                LF++FY+s ++l q + a++L+
  EEA20429.1 52 LFFCFYHSDRPLTQQALARALS 73
                9**************9999996 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 4.6
    NOT2_3_5  93 keepkekteeyekgsYkyFD 112
                 ++e +  +e+ e++++  FD
  EEA20429.1 318 GSEDDDDEEDDENDEWDGFD 337
                 22223333444777777776 PP

>> LRIF1  Ligand-dependent nuclear receptor-interacting factor 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   4.0    0.0002      0.51     584     635 ..     132     182 ..     124     205 .. 0.70

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0002
       LRIF1 584 vvkltkeieeekkkikleqdlskKRkaktsklvdsaKrrktsnksstssnse 635
                  +k  ++++ee+   + +++ +kKRk k   +  ++Krrk+s ++++  +  
  EEA20429.1 132 NDKSGEQQQEED-AGTKDDEGNKKRKRKGDDKAKNGKRRKQSDDNDAKASGS 182
                 444434444444.45667778999999999*********9998776655432 PP

>> Afi1  Docking domain of Afi1 for Arf3 in vesicle trafficking
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   2.4   0.00047       1.2      59     122 ..     136     198 ..     109     203 .. 0.57
   2 ?    3.8   0.8     0.029        75      82     101 ..     300     332 ..     229     338 .] 0.61

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00047
        Afi1  59 teeeeleeeekknklekrkkkksededdvdeedeeeeddnedldelskdeeekagegepllyvl 122
                  e+++ ee++ +++ e +kk+k++ +d+ ++ +  +++d++d +  ++ +++++g+  +l  ++
  EEA20429.1 136 GEQQQ-EEDAGTKDDEGNKKRKRKGDDKAKNGKRRKQSDDNDAKASGSEQQQQGGKWTELESYI 198
                 22222.2333333333333333343455555566665666666555566655566666555555 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.029
        Afi1  82 e.............deddvdeedeeeeddnedl 101
                 +             ++++ +e+d++eedd++d+
  EEA20429.1 300 DderlvewgfrerkKKTNGSEDDDDEEDDENDE 332
                 023333333332224444455555555555444 PP

>> TRAP_alpha  Translocon-associated protein (TRAP), alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.5    0.0062        16      28      76 ..     136     176 ..     111     190 .. 0.37
   2 ?    5.9   0.9    0.0025       6.4       5      65 ..     271     331 ..     269     336 .. 0.64

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.0062
  TRAP_alpha  28 aaeedevddelvdveaedeeveeeeeeeeeeeeeeeedeeelkaspdad 76 
                   +++e d  ++d e++++++ + +++ ++ +        + k+s d d
  EEA20429.1 136 GEQQQEEDAGTKDDEGNKKRKRKGDDKAKNGK--------RRKQSDDND 176
                 11111122223333332222222222211111........222222222 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0025
  TRAP_alpha   5 llllvlpavllllssatkvvaaaaaeedevdde.lvdveaedeeveeeeeeeeeeeeeeeed 65 
                 + ll+ p+  l ++s+tk+v ++  e + +dde lv+    +++++++ +e+++ ee++e+d
  EEA20429.1 271 IELLLRPFEKLNKESQTKSVRMK-VESEVLDDErLVEWGFRERKKKTNGSEDDDDEEDDEND 331
                 56889999999998888855555.55556777757777776666666666655444444444 PP

>> AP3D1  AP-3 complex subunit delta-1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   9.5    0.0016         4      65     117 ..     131     184 ..     119     192 .. 0.69
   2 ?    5.3   1.2    0.0083        21      36     117 ..     249     329 ..     234     335 .. 0.49

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0016
       AP3D1  65 rsdkyleeeesrkakkkakeekkkkkkkkkkkkkkkkkkkkkk.eeesseseed 117
                   dk  e+++++ a  k +e +kk+k+k++ k k+ k++k+ + ++ + + +e 
  EEA20429.1 131 INDKSGEQQQEEDAGTKDDEGNKKRKRKGDDKAKNGKRRKQSDdNDAKASGSEQ 184
                 457777888888888888888889999999999988844444314444444444 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0083
       AP3D1  36 ssaqnseeveeipvaeldlsvplkvpglkrsdkyleeeesrkakkkakeekkkkkkkkkkkkkkkkkkkkkkeeesseseed 117
                 ss++++++ ee+  ++  l+vp++       +k  +e++ ++ + k+++e  ++ +  +   +++kkk + +e+ ++e++++
  EEA20429.1 249 SSYDSDDQNEEVVPVKDRLDVPIELLL-RPFEKLNKESQTKSVRMKVESEVLDDERLVEWGFRERKKKTNGSEDDDDEEDDE 329
                 555566555665555666666655544.445555555444444445554444444444444444442222222222222222 PP

>> Connexin  Connexin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.1   0.00021      0.55      82     146 ..     115     179 ..      98     201 .. 0.55
   2 ?   -4.2   1.1       4.5   1.2e+04     126     126 ..     312     312 ..     279     332 .. 0.39

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00021
    Connexin  82 lvstPsllylvyvlhkiakeekekekeeeekeeeekeeekkkkkekkkkkkkeeekekkkeegkr 146
                 + +   + + +y   ki+ ++ e+++ee++ +++++ ++k+k+k ++k k+ +++k+++++++k+
  EEA20429.1 115 IRCYVGVAFEIYLKGKINDKSGEQQQEEDAGTKDDEGNKKRKRKGDDKAKNGKRRKQSDDNDAKA 179
                 55556677788888888888887777777777777777776633333333322222222222222 PP

  == domain 2  score: -4.2 bits;  conditional E-value: 4.5
    Connexin 126 e 126
                 +
  EEA20429.1 312 R 312
                 1 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (338 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1392  (0.0776396); expected 358.6 (0.02)
Passed bias filter:                      679  (0.0378716); expected 358.6 (0.02)
Passed Vit filter:                       104  (0.00580066); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.64u 0.34s 00:00:00.98 Elapsed: 00:00:00.48
# Mc/sec: 2135.43
//
Query:       EEA20430.1  [L=300]
Description: ubiquitin domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    4.7e-42  142.5   0.0      1e-41  141.4   0.0    1.6  1  UBD        Ubiquitin-binding domain
    5.1e-06   26.2   0.0    7.4e-06   25.6   0.0    1.3  1  ubiquitin  Ubiquitin family
    7.6e-05   23.2   0.3    0.00022   21.8   0.0    1.8  2  DUF2407    DUF2407 ubiquitin-like domain
     0.0069   16.2   0.0      0.015   15.2   0.0    1.5  1  Rad60-SLD  Ubiquitin-2 like Rad60 SUMO-like


Domain annotation for each model (and alignments):
>> UBD  Ubiquitin-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  141.4   0.0   2.3e-45     1e-41       2     104 .]      67     168 ..      66     168 .. 0.98

  Alignments for each domain:
  == domain 1  score: 141.4 bits;  conditional E-value: 2.3e-45
         UBD   2 nkplrkekkwtskkrpltraqlerereeFfdTrvtgrkeiWdalkaalevleeddlataqaildaaeitlptgdlaegvYDelGalYelpeyvvsdPtn 100
                 n+p+r +++w+sk+r +tr+q++rereeFfdTrvtgr+e+W+al aal+++++++++taq i+daa++t+ptgdl+eg+YDe+G lY+lp+++vsdP n
  EEA20430.1  67 NQPIR-PHVWRSKRRLWTRTQIDREREEFFDTRVTGRTEVWAALGAALSLMRDGEIETAQGIIDAAGVTVPTGDLCEGCYDENGVLYRLPQCIVSDPDN 164
                 899*9.********************************************************************************************* PP

         UBD 101 lied 104
                 +++d
  EEA20430.1 165 IVDD 168
                 *976 PP

>> ubiquitin  Ubiquitin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.0   1.6e-09   7.4e-06      10      69 ..     235     295 ..     222     298 .. 0.89

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 1.6e-09
                 EEEEEEETTSBHHHHHHHHHHHHTSSGGGE.EEEETTEEE-TTSBHGGHTTSTTEEEEEEE CS
   ubiquitin  10 kitleveesdtveelKekiaekegipaeqq.rLiysGkvLedertleeygiqdgstlhlvl 69 
                 ++ +++e+++tv  l  k++++ ++p  +  r++y G+ L+++++l + g ++g +++ ++
  EEA20430.1 235 DVVISIEKTQTVGVLARKVQSEVKMPNTHRiRIVYLGRMLRESEPLVDQGWKPGQVINAMV 295
                 7889********************9986655**************************9987 PP

>> DUF2407  DUF2407 ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.1       1.5   6.6e+03      34      40 ..      39      45 ..      11      72 .. 0.59
   2 !   21.8   0.0   4.8e-08   0.00022       6      64 ..     227     283 ..     221     296 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 1.5
     DUF2407 34 Rerlpae 40
                R++  ++
  EEA20430.1 39 RQQASNS 45
                2222222 PP

  == domain 2  score: 21.8 bits;  conditional E-value: 4.8e-08
     DUF2407   6 RFsa.sipDleLdipdpntttvagLkqliRerlpaelasrrLrLIyaGrlLedttslass 64 
                 R+s+   pD+ ++i+  +t tv  L + + +++ +  +++r+r++y Gr+L+++++l ++
  EEA20430.1 227 RLSDrGGPDVVISIE--KTQTVGVLARKVQSEV-KMPNTHRIRIVYLGRMLRESEPLVDQ 283
                 55556789*******..7889999*********.88899***************999765 PP

>> Rad60-SLD  Ubiquitin-2 like Rad60 SUMO-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   3.2e-06     0.015       8      72 .]     231     295 ..     227     295 .. 0.92

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 3.2e-06
                 SSS--EEEEEETTSBHHHHHHHHHHHHT----TT-EEEETTEE--TTSBGGGSS--TTEEEEEEX CS
   Rad60-SLD   8 kdgkevkikVkptttvskLieayrkkkgipeeqkvrLiFDGeeLdpnstvedldiedgdtidvvi 72 
                  +g +v i++++t tv  L+++ +++++ p++ ++r+++ G+ L++ + + d++ + g +i +++
  EEA20430.1 231 RGGPDVVISIEKTQTVGVLARKVQSEVKMPNTHRIRIVYLGRMLRESEPLVDQGWKPGQVINAMV 295
                 5667899**********************************************999999998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (300 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       858  (0.0478554); expected 358.6 (0.02)
Passed bias filter:                      468  (0.026103); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.45
# Mc/sec: 1983.83
//
Query:       EEA20431.1  [L=299]
Description: ubiquitin domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.6e-42  142.5   0.0      1e-41  141.4   0.0    1.6  1  UBD       Ubiquitin-binding domain


Domain annotation for each model (and alignments):
>> UBD  Ubiquitin-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  141.4   0.0   5.6e-46     1e-41       2     104 .]      67     168 ..      66     168 .. 0.98

  Alignments for each domain:
  == domain 1  score: 141.4 bits;  conditional E-value: 5.6e-46
         UBD   2 nkplrkekkwtskkrpltraqlerereeFfdTrvtgrkeiWdalkaalevleeddlataqaildaaeitlptgdlaegvYDelGalYelpeyvvsdPtn 100
                 n+p+r +++w+sk+r +tr+q++rereeFfdTrvtgr+e+W+al aal+++++++++taq i+daa++t+ptgdl+eg+YDe+G lY+lp+++vsdP n
  EEA20431.1  67 NQPIR-PHVWRSKRRLWTRTQIDREREEFFDTRVTGRTEVWAALGAALSLMRDGEIETAQGIIDAAGVTVPTGDLCEGCYDENGVLYRLPQCIVSDPDN 164
                 899*9.********************************************************************************************* PP

         UBD 101 lied 104
                 +++d
  EEA20431.1 165 IVDD 168
                 *976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (299 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       878  (0.0489709); expected 358.6 (0.02)
Passed bias filter:                      475  (0.0264934); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2108.96
//
Query:       EEA20432.1  [L=722]
Description: G-patch domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.8e-44  148.4   4.5    1.1e-43  146.9   2.6    2.6  2  DUF1604    Protein of unknown function (DUF1604)
    6.5e-07   29.1   1.7      2e-06   27.6   1.7    1.8  1  G-patch    G-patch domain
  ------ inclusion threshold ------
      0.011   15.9   0.3      0.058   13.5   0.0    2.5  2  G-patch_2  G-patch domain


Domain annotation for each model (and alignments):
>> DUF1604  Protein of unknown function (DUF1604)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  146.9   2.6   1.9e-47   1.1e-43       1      85 []      41     125 ..      41     125 .. 0.98
   2 ?   -0.5   0.0      0.19   1.1e+03      23      37 ..     267     281 ..     254     283 .. 0.88

  Alignments for each domain:
  == domain 1  score: 146.9 bits;  conditional E-value: 1.9e-47
     DUF1604   1 avpvwkqevtdekgrrrlhGAftGGfsaGyfntVGskeGwtPstfkSsrkerakkakkqrvedfmDeedleeleeskkletkeef 85 
                 +vpvwkqevtde+gr+rlhGAftGGfsaGyfntVGskeGwtPstf+Ssr++rak++k+q++edfmDeed++e+eesk+l+t+e+f
  EEA20432.1  41 YVPVWKQEVTDERGRKRLHGAFTGGFSAGYFNTVGSKEGWTPSTFVSSRQNRAKDRKQQKIEDFMDEEDIREAEESKQLHTSEDF 125
                 689******************************************************************************9987 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.19
     DUF1604  23 tGGfsaGyfntVGsk 37 
                  GGf  G  n  Gs 
  EEA20432.1 267 RGGFGVGILNDTGSD 281
                 6**********9997 PP

>> G-patch  G-patch domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.6   1.7   3.3e-10     2e-06       2      28 ..     150     176 ..     149     177 .. 0.87

  Alignments for each domain:
  == domain 1  score: 27.6 bits;  conditional E-value: 3.3e-10
     G-patch   2 sniGvkmLqkmGWkpGqGLGkkeqGia 28 
                 + +Gvk+L++mGW++GqG+G k  ++a
  EEA20432.1 150 ETMGVKLLKRMGWREGQGIGPKVRRRA 176
                 578*****************9877765 PP

>> G-patch_2  G-patch domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   9.6e-06     0.058      17      40 ..     152     175 ..     150     221 .. 0.70
   2 ?   -3.8   0.1       2.5   1.5e+04      45      56 ..     262     273 ..     254     277 .. 0.53

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 9.6e-06
   G-patch_2  17 FGaAlLrGMGWkegqgigknkkgr 40 
                  G  lL+ MGW egqgig +   r
  EEA20432.1 152 MGVKLLKRMGWREGQGIGPKVRRR 175
                 5888**************997666 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 2.5
   G-patch_2  45 epkrRpgrlGLG 56 
                  + +R g+ G G
  EEA20432.1 262 NQVPRRGGFGVG 273
                 344555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (722 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       398  (0.0221987); expected 358.6 (0.02)
Passed bias filter:                      298  (0.0166211); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.70u 0.33s 00:00:01.03 Elapsed: 00:00:00.54
# Mc/sec: 4044.42
//
Query:       EEA20433.1  [L=1073]
Description: serine/threonine protein kinase Kin1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.2e-70  237.1   0.0    3.1e-70  236.6   0.0    1.2  1  Pkinase        Protein kinase domain
    2.9e-40  138.2   0.0    6.6e-40  137.0   0.0    1.5  1  Pkinase_Tyr    Protein tyrosine kinase
      9e-17   60.6   0.4    1.6e-16   59.8   0.4    1.4  1  KA1            Kinase associated domain 1
      1e-05   25.0   0.0    0.00024   20.5   0.0    2.2  2  Kinase-like    Kinase-like
    1.9e-05   24.1   0.0    3.3e-05   23.3   0.0    1.3  1  Kdo            Lipopolysaccharide kinase (Kdo/WaaP) family
    0.00012   21.2   0.0    0.00019   20.5   0.0    1.2  1  Haspin_kinase  Haspin like kinase domain
     0.0012   18.8   0.1     0.0077   16.2   0.0    2.2  2  APH            Phosphotransferase enzyme family
  ------ inclusion threshold ------
      0.073   12.6   0.0       0.15   11.6   0.0    1.4  1  YrbL-PhoP_reg  PhoP regulatory network protein YrbL
      0.085   12.4   0.2       0.22   11.1   0.2    1.7  1  RIO1           RIO1 family
       0.15   12.3   0.0       0.32   11.1   0.0    1.5  1  ABC1           ABC1 family


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  236.6   0.0   1.7e-73   3.1e-70       4     264 .]     177     437 ..     174     437 .. 0.93

  Alignments for each domain:
  == domain 1  score: 236.6 bits;  conditional E-value: 1.7e-73
                 EEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHH............HHHHHHHHHHHHHSCTTB--EEEEEEESSEEEEEEE--TTEBHHHHHH CS
     Pkinase   4 leklGeGsfGkVykaveketgkivAvKkikkekakkkke............kkvlrEikilkklkhpnivrlyevfeekdelylvleyveggeladlle 90 
                  +++G Gs+GkV  a++ etg++vAvK++ ++ +++ +              +++rE +i+  ++hp+++ + +v++++ + y+++eyv+gg++ d++ 
  EEA20433.1 177 GKTIGAGSMGKVKIAKNIETGEQVAVKVVPRQTTEEHRSgrdaeradrskeIRTAREAAIVSLVDHPYVCGMRDVVRTPYHWYMLFEYVNGGQMLDYII 275
                 689**************************99998887778889999999878899**************************************999999 PP

                 HHSS--HHHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCSBCTTTSCGGGS-HHHHTTSCB.SHHHHHHHHHHHHH CS
     Pkinase  91 rkgslseeeakkiakqilegleylHskgiiHrDlKpeNiLidekgelKitDFGlakelessskltsfvgtseYlAPEvlkeney.skkvDvWslGvily 188
                  +g+l+e++a+k+a+qi+++l+y+H+++i+HrDlK eNiLi+++g++Ki+DFGl++ ++ +s+l++f+g+ ++ APE+l++++y +++vDvWs G++ly
  EEA20433.1 276 SHGKLKEKQARKFARQIASALDYCHRNSIVHRDLKIENILISKTGDIKIIDFGLSNLFSPRSHLRTFCGSLYFAAPELLQARQYtGPEVDVWSFGIVLY 374
                 9******************************************************************************9999999************* PP

                 HHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCTSHH...HHHTTS-HHHHHHHHHHT-SSGCCSTTHHHHHTSGGG CS
     Pkinase 189 elltgkppfsgekgkekvekeldqlekilkilgetkeklpeaseiseeakdllkkllkkdpkkRltaeellqhpyl 264
                  l++gk pf ++ +      +l+      k    +k +++ ++ + +e++++++++l  dpkkR + +e+++hp++
  EEA20433.1 375 VLVCGKVPFDDQ-SMP----NLHA-----K---IKKGEVEYPQGLTSECRHIISRMLVTDPKKRASLAEIMNHPWM 437
                 **********33.333....3333.....2...2345789999********************************7 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.0   0.0   3.7e-43   6.6e-40       3     257 ..     176     433 ..     174     434 .. 0.86

  Alignments for each domain:
  == domain 1  score: 137.0 bits;  conditional E-value: 3.7e-43
                  EEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEEST.............TSSHHHHHHHHHHHHHHHTS-BTTB--EEEEEESSSSEEEEEE--TTEB CS
  Pkinase_Tyr   3 lgkklGeGafGkVvegtlkgekekkevkVavKtlke.............eateeekeelleeakimkklkhpnivkllgvctkeepllivteyvkgGd 87 
                  lgk++G+G+ GkV  ++      ++ ++VavK++ +             +a+++++ +  +ea+i + ++hp +  +  v+    + ++++eyv+gG+
   EEA20433.1 176 LGKTIGAGSMGKVKIAKNI----ETGEQVAVKVVPRqtteehrsgrdaeRADRSKEIRTAREAAIVSLVDHPYVCGMRDVVRTPYHWYMLFEYVNGGQ 269
                  789************9999....7888999999865122222222222122333344567899999999*************99************** PP

                  HHHHHHHTCTTTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEETTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSEEE.H CS
  Pkinase_Tyr  88 LlkfLrkkekekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsenkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekkft.s 184
                  +l+++ ++   kl+ k+  +fa q+A++++y +++++vHrdl   N+L+s++  +ki DfGL++  + +++    ++   ++ + apE l+++++t  
   EEA20433.1 270 MLDYIISH--GKLKEKQARKFARQIASALDYCHRNSIVHRDLKIENILISKTGDIKIIDFGLSNLFSPRSHL---RTFCGSLYFAAPELLQARQYTgP 362
                  *******9..9*******************************************************444444...3455678999*********9945 PP

                  HHHHHHHHHHHHHHHTTSSGTTTTSHHHHHHHHHHTTEES-BBTTSBHHHHHHHHHHT-SSGGGS--HHHHHH CS
  Pkinase_Tyr 185 ksDvWsfGvllwEiftlgespypglkneevleklkegkrlekpekcpeelyelmkkcweedpeeRptfselve 257
                  + DvWsfG++l+ +++ g+ p+ + +  ++ +k+k+g+ +e p+  ++e  +++++ + +dp++R++++e+++
   EEA20433.1 363 EVDVWSFGIVLYVLVC-GKVPFDDQSMPNLHAKIKKGE-VEYPQGLTSECRHIISRMLVTDPKKRASLAEIMN 433
                  89**********9998.*****************9986.899***************************9986 PP

>> KA1  Kinase associated domain 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.8   0.4   9.1e-20   1.6e-16       2      45 .]    1030    1073 .]    1029    1073 .] 0.98

  Alignments for each domain:
  == domain 1  score: 59.8 bits;  conditional E-value: 9.1e-20
         KA1    2 vvkFEievcKlpelslygvrfkRlsGdtwqYkrlasqilseLkL 45  
                  v++FEi ++K+p+ sl+g++fk++sG +wqY+++a++il+ L+L
  EEA20433.1 1030 VLRFEILIVKVPLFSLHGIQFKKVSGGMWQYREMAKRILDALRL 1073
                  79****************************************98 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0     0.057     1e+02      13      59 ..     173     222 ..     164     234 .. 0.78
   2 !   20.5   0.0   1.3e-07   0.00024     157     254 ..     296     387 ..     269     425 .. 0.75

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.057
  Kinase-like  13 tlvrgellkkgdrsvvfevkdqetgeplavkvf...llpseaskkdlerl 59 
                  +   g+ ++ g  ++v  +k+ etge++avkv    +++++ s +d er 
   EEA20433.1 173 QWALGKTIGAGSMGKVKIAKNIETGEQVAVKVVprqTTEEHRSGRDAERA 222
                  566788999999*******************9633255557777777765 PP

  == domain 2  score: 20.5 bits;  conditional E-value: 1.3e-07
  Kinase-like 157 aanLqakglvhgkftvdnllldekgglmlggf..taLvragtkvvlseve..kgfaPpEllgsrggytrknktkmthkldaWqlGlviyriwclklPl 250
                    + + + +vh +++ +n+l  + g +++ +f  ++L+    + +  + +    fa pEll +r+            ++d+W  G+v y + c k+P+
   EEA20433.1 296 LDYCHRNSIVHRDLKIENILISKTGDIKIIDFglSNLFSPRSHLR--TFCgsLYFAAPELLQARQY--------TGPEVDVWSFGIVLYVLVCGKVPF 383
                  56778899*********************9983346777777776..55434789******99554........3468******************** PP

  Kinase-like 251 tlat 254
                  + + 
   EEA20433.1 384 DDQS 387
                  9753 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.3   0.0   1.8e-08   3.3e-05      90     167 ..     256     328 ..     230     340 .. 0.88

  Alignments for each domain:
  == domain 1  score: 23.3 bits;  conditional E-value: 1.8e-08
         Kdo  90 yrAlllterlegaqdLedllakwaelaeelkrallkavgrliaklhragvnHadlyaknillqqeeeeeaeiwliDld 167
                 y+  +l e ++g q L+ ++  + +l+e+  r+  ++++ +    hr  + H+dl + nil+ +++     i +iD+ 
  EEA20433.1 256 YHWYMLFEYVNGGQMLDYIIS-HGKLKEKQARKFARQIASALDYCHRNSIVHRDLKIENILISKTG----DIKIIDFG 328
                 777899999999999999998.6889***************************************9....99999996 PP

>> Haspin_kinase  Haspin like kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5   0.0   1.1e-07   0.00019     122     257 ..     196     333 ..     170     343 .. 0.68

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 1.1e-07
  Haspin_kinase 122 kdkevvlKviplevledvtis.kelslkelkslklvkgtypglllllqdkvlkekpdfyseqql.flvlllkdkGtdLeev....klkswkqalsi 211
                    + ++v++Kv+p ++ e+ +      +   +k+++  + +   + l+ + +v   + d++++  + +++ +  ++G+ L+ +    klk  kqa + 
     EEA20433.1 196 TGEQVAVKVVPRQTTEEHRSGrDAERADRSKEIRTAREA-AIVSLVDHPYVCGMR-DVVRTPYHwYMLFEYVNGGQMLDYIishgKLK-EKQARKF 288
                    566777777777777777776445555777777777777.333333334444444.66665544144445566777766655432444.4788888 PP

  Haspin_kinase 212 fwqivkiLyvaEtkfeFEHRdLhldniLvdknlnvtlidlklsRle 257
                      qi++ L          HRdL+++niL+ k++ + +id+ ls l 
     EEA20433.1 289 ARQIASALDYCHR-NSIVHRDLKIENILISKTGDIKIIDFGLSNLF 333
                    8888888887755.4788**********************999775 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0     0.069   1.2e+02      69     102 ..     256     296 ..     193     303 .. 0.63
   2 !   16.2   0.0   4.3e-06    0.0077     147     196 ..     287     330 ..     269     335 .. 0.69

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.069
                 E.EEEEEE----EE-SS......HHHHHHHHHHHHHHHHHH CS
         APH  69 l.lfalieyvpgrsllr......klsaaqlpellealgefl 102
                 +  + l+eyv g ++l+      kl ++q+++++++++++l
  EEA20433.1 256 YhWYMLFEYVNGGQMLDyiishgKLKEKQARKFARQIASAL 296
                 2367899************8888888888888888888877 PP

  == domain 2  score: 16.2 bits;  conditional E-value: 4.3e-06
                 HHHHHHHHHHHHH--SSS-EEEE-SS-SGGGEEEC..TTEEEEE---TT- CS
         APH 147 eleeqvlaalaallpgelptvllHgDlhpgNllvdpddgrvtGviDfeda 196
                 ++++    ++a  l+   + +++H+Dl+  N+l+ ++++    +iDf+++
  EEA20433.1 287 KFAR----QIASALDYCHRNSIVHRDLKIENILISKTGDIK--IIDFGLS 330
                 3333....333333335579***************555554..****986 PP

>> YrbL-PhoP_reg  PhoP regulatory network protein YrbL
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   8.4e-05      0.15     119     183 ..     283     342 ..     266     345 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 8.4e-05
  YrbL-PhoP_reg 119 eltaelkeaLdefleelldnhivtndlsakNivvkknsegeeelvlvDGlGektliplyawsrtl 183
                    + + + ++++   l+++  n iv +dl+++Ni++ k    +    ++D +G ++l+  ++ +rt+
     EEA20433.1 283 KQARKFARQIASALDYCHRNSIVHRDLKIENILISKTGDIK----IID-FGLSNLFSPRSHLRTF 342
                    3334678899999********************99876555....776.7777777777777666 PP

>> RIO1  RIO1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.2   0.00012      0.22      84     150 ..     261     328 ..     190     333 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00012
                 EEE--EETTEEGGBHHHCG.-HHHHHHHHHHHHHHHHHHHHTSTEEESS-STTSEEEETT.EEEE--GT CS
        RIO1  84 vmefigedgvaapklkdve.eeeeaeelyeevleemrklykeaglvHaDLSeyNvlvded.kvviIDvs 150
                 + e+++  ++  + +++ + +e++a++ ++++ +++    +++ +vH DL   N+l+++  ++ iID++
  EEA20433.1 261 LFEYVNGGQMLDYIISHGKlKEKQARKFARQIASALD-YCHRNSIVHRDLKIENILISKTgDIKIIDFG 328
                 5566664444455555566447778888888777555.55699**************9998******96 PP

>> ABC1  ABC1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00018      0.32      17      44 ..     178     206 ..     176     220 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00018
        ABC1  17 ePiAaASiaqVhrAklk.sgeeVavKvqr 44 
                 ++i+a+S+++V  Ak   +ge+VavKv  
  EEA20433.1 178 KTIGAGSMGKVKIAKNIeTGEQVAVKVVP 206
                 579***********98879*******975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1073 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       768  (0.0428356); expected 358.6 (0.02)
Passed bias filter:                      425  (0.0237046); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 1.00u 0.38s 00:00:01.38 Elapsed: 00:00:00.58
# Mc/sec: 5608.48
//
Query:       EEA20434.1  [L=633]
Description: histone-lysine N-methyltransferase Clr4 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-17   63.5   0.0    1.5e-16   61.3   0.0    2.2  2  SET       SET domain
      6e-14   52.6   3.0      6e-14   52.6   3.0    2.2  2  Pre-SET   Pre-SET motif
  ------ inclusion threshold ------
      0.023   14.7   0.5      0.023   14.7   0.5    2.7  3  AWS       AWS domain


Domain annotation for each model (and alignments):
>> SET  SET domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0       1.3   7.8e+03      52      89 ..     388     428 ..     304     433 .. 0.67
   2 !   61.3   0.0   2.4e-20   1.5e-16       1     169 []     460     591 ..     460     591 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 1.3
                 X...HHHHHHHTTSSHHHHHHHHHHHHHHHHHHTHHHHHHH CS
                 x...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         SET  52 t...kelakasastllqklakdqkqaekedtdaalkasska 89 
                 t   ke+++ s + ++     + k ++ked+ ++ ++++++
  EEA20434.1 388 TclsKEEEEDSEELMVPYEHRNGKLLLKEDFINRKVMIYEC 428
                 34445555555555555555666666777777777766655 PP

  == domain 2  score: 61.3 bits;  conditional E-value: 2.4e-20
                 SCEEEESSXBXTTXEEEEEE.ECCEECHHHHHHHHHH...........HTEEEEEXGGXXGGSX...HHHHHHHTTSSHHHHHHHHHHHHHHHHHHTHH CS
                 xxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx...........xxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         SET   1 GrGvfAtedIpkgeficeyp.eeiiltkdeadksele...........aylfslpeapknlaft...kelakasastllqklakdqkqaekedtdaalk 84 
                 G+G+++++ I  g+fi +y  e  ++t++ea+++e+             ylfsl+       +    +e                              
  EEA20434.1 460 GFGLRSLDFIHGGQFIDIYLgE--VITSAEAELREDAtmgsngshtspSYLFSLD-------WFppsSE------------------------------ 519
                 99**************656667..99*****9999999***************99.......3222211.............................. PP

                 HHHHHXTTTSXXXHCCCCC.HCCCHEEEETEEEEEECCCGTTGGGCEEXSSSSEEEEEEEE....TTSSEEEEEESSXBXTTEEEEEXTT CS
                 xxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxx RF
         SET  85 asskaesdlnaskpeagaf.saiagysidaralksgngagplarflNHsCdpNcnltvqnv....lrgprvavfAtrdIkkGeEltidYg 169
                             +  + ++ ++   y++d   +  g+++    rf+NHsC+pNc++  ++     ++ + +a+fA+rdI++G Elt+dY+
  EEA20434.1 520 ------------DDDDDDEeEGGTHYVVD--GQRFGGPS----RFMNHSCNPNCKMIPVSThhgdQKIYDLAFFARRDIPPGVELTFDYN 591
                 ............11122223556679999..88******....***********5555555****************************7 PP

>> Pre-SET  Pre-SET motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.6   3.0     1e-17     6e-14       6     109 .]     333     441 ..     328     441 .. 0.80
   2 ?   -3.5   2.4       2.7   1.6e+04      98     106 ..     607     615 ..     538     618 .. 0.65

  Alignments for each domain:
  == domain 1  score: 52.6 bits;  conditional E-value: 1e-17
                 SSS-EEEE-SSSS-.-CGCCSEE-SS-EE-TTS-.-CCC--.....----TTCC-TCCTTSCCCT....CTTTSB-SSBBT...TTSB.H.....CH-S CS
     Pre-SET   6 ekvpipvvnevdse.lppakfeYikknilsegve.dkeslarseesgCeCkgdClsssskcaCaq....keeeeeflaYde...kgllke.....eekk 90 
                 +  p+++  + d +  + ++fe++++++l++gv+  +e +    + gC+C ++C  ++s+c+C++    +++ee +++Y++   k  l       ++k 
  EEA20434.1 333 QGPPVTMARDWDGTgSLASNFEFTNTYKLQKGVTrADEGF----NYGCDCGTQC--DPSRCTCLSkeeeEDSEELMVPYEHrngK--LLLkedfiNRKV 423
                 567999999999998889***********99999644444....57****999*..79******966654455567899987542..322458889*** PP

                 EEE---TTSSS.-TT-TT- CS
     Pre-SET  91 piyECnekCkCssksCknR 109
                 +iyEC++ C+C + +C nR
  EEA20434.1 424 MIYECSSLCPCLP-TCWNR 441
                 ***********76.****9 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 2.7
                 TSSS.-TT- CS
     Pre-SET  98 kCkCssksC 106
                 kC C +++C
  EEA20434.1 607 KCLCGEARC 615
                 455544444 PP

>> AWS  AWS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -5.6   6.2         3   1.8e+04      25      32 ..     376     383 ..     373     389 .. 0.79
   2 ?   14.7   0.5   3.8e-06     0.023      12      38 ..     419     445 ..     414     446 .. 0.84
   3 ?   -4.5   1.0         3   1.8e+04      25      31 ..     608     615 ..     606     618 .. 0.59

  Alignments for each domain:
  == domain 1  score: -5.6 bits;  conditional E-value: 3
         AWS  25 CpcGerCq 32 
                 C cG +C 
  EEA20434.1 376 CDCGTQCD 383
                 88888884 PP

  == domain 2  score: 14.7 bits;  conditional E-value: 3.8e-06
         AWS  12 iNR.mlliECteetCpcGerCqNqrfqr 38 
                 iNR ++ +EC++ +Cpc   C N+  q+
  EEA20434.1 419 INRkVMIYECSS-LCPCLPTCWNRLVQH 445
                 89945789***9.**********98876 PP

  == domain 3  score: -4.5 bits;  conditional E-value: 3
         AWS  25 CpcGe.rC 31 
                 C cGe rC
  EEA20434.1 608 CLCGEaRC 615
                 66765345 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (633 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       631  (0.0351944); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.75u 0.39s 00:00:01.14 Elapsed: 00:00:00.59
# Mc/sec: 3224.40
//
Query:       EEA20435.1  [L=193]
Description: hypothetical protein PMAA_042750 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (193 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       332  (0.0185175); expected 358.6 (0.02)
Passed bias filter:                      197  (0.0109878); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.62u 0.36s 00:00:00.98 Elapsed: 00:00:00.60
# Mc/sec: 969.23
//
Query:       EEA20436.1  [L=410]
Description: endo-beta-1,6-glucanase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
      6e-15   55.4   7.3    7.5e-15   55.1   7.3    1.1  1  Cellulase  Cellulase (glycosyl hydrolase family 5)


Domain annotation for each model (and alignments):
>> Cellulase  Cellulase (glycosyl hydrolase family 5)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.1   7.3   4.2e-19   7.5e-15       5     279 ..      91     379 ..      87     381 .. 0.72

  Alignments for each domain:
  == domain 1  score: 55.1 bits;  conditional E-value: 4.2e-19
                 SEEEEGEEECETTSCGGSHHHHHHHHHHHT-SEEEEEEEC...TGGTTSSTTTGCTHHHHHHHHHHHHHHHHTT-EEEEEEESS........TTT...C CS
   Cellulase   5 gkpvnlkglstswgnpyttkalidevkdagfntvRlpvsw...gelvenapdykvdenslerveevvkyakenglyvildiHse........egw...l 89 
                 g++++ +++  +wg+    +  i+++ + g n++R+pv++   + +v ++++  + + +l+ +e++  +a + g+y+i+d+H          +     +
  EEA20436.1  91 GQETANTNFADHWGSW-IVENDIATMSSYGLNAIRIPVGYwmrEDIVYSDSE-HFPQGALSYLEQICGWASDYGFYIIIDLHGApgaqvahnA-DtgqY 186
                 6777667778889986.7788889999***********95487666655555.4999***************************664444431.03445 PP

                 SSSSTTTTHHHHHHHHHHHHHHHHHHHTTTTT..TE.EEESSSS--STTCTCCTCHHHTTHHHHHHHHHHHHHHHHTTSSEEEEECHHHHTBHHHHHCT CS
   Cellulase  90 tkadgnssedtaeeffkklwtqiAerykknde..vv.ifelmNEPhgnntgaewtseeadevkayaeeaikaIRavgpnrliivegnswsgnldgavln 185
                  + +g  ++++ e  +k  ++++ ++  ++d+  +v +  ++NEP + +++  +     +    y+  a+  IRa+     i  +++   + ++    n
  EEA20436.1 187 APTPGFYVDYQFERALKF-LEWMTTQIHSSDSfrNVgMLGIVNEPVQDSSQ-VG-----TMRSTYYPDAFSRIRAAERALGITANNELHIQ-MM----N 273
                 666666666665555544.888888887666555552679*******7665.45.....7788899**********997777666633222.22....1 PP

                 ......SG....SSSSTTEEEEEEEETTTHHHTGCGSHSCTHHHHHHHHHHHHHHHHHHTTSEEEEEEEESS......TTSSH......HHHHHHHHH. CS
   Cellulase 186 ......dP....ndsqdnliysvHfYgpsdfaqtefgkdltdktnlaqrledaakylvekgipviigEfGgs......nadgd......lakeeaekw. 261
                       dP    +d +   +y+ H Y  +d +   +          ++++++  +  +  + p ii+E+ +s      +   +      ++k+  +kw 
  EEA20436.1 274 nlwgsgDPteylTD-NYFAAYDDHRYVKWDTSVAVS---------QDNYISTSCNDNRGGNTPTIISEWSLSvpdnvqD---TagwdpsTNKDFYAKWf 359
                 12344688544433.5678999********655444.........67788888888899999*********97764441...25556888888899998 PP

                 .HHHH.HHTTTEEEEEEESS CS
   Cellulase 262 .ldyl.kekgiswiyWslnp 279
                  ++++  ek+ +w++Ws+++
  EEA20436.1 360 aAQVItYEKQDGWLFWSWKS 379
                 7555546779********87 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (410 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       362  (0.0201908); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.36s 00:00:00.99 Elapsed: 00:00:00.56
# Mc/sec: 2212.41
//
Query:       EEA20437.1  [L=2116]
Description: calcium channel subunit Cch1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
     8e-121  401.9  90.0    5.2e-42  143.8   5.2    4.9  4  Ion_trans  Ion transport protein
    0.00036   20.2   0.0     0.0013   18.4   0.0    2.0  2  GPHH       Voltage-dependent L-type calcium channel, IQ-assoc
  ------ inclusion threshold ------
      0.016   14.7   0.0      0.038   13.5   0.0    1.7  1  EF-hand_1  EF hand
      0.018   14.9   0.0      0.077   13.0   0.0    2.1  1  EF-hand_6  EF-hand domain


Domain annotation for each model (and alignments):
>> Ion_trans  Ion transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  143.8   5.2   1.2e-45   5.2e-42       3     244 ..     345     727 ..     343     728 .. 0.92
   2 !   83.6  23.5   2.7e-27   1.2e-23       5     239 ..     761     990 ..     758     996 .. 0.87
   3 !  110.1  17.3   2.2e-35   9.7e-32       5     241 ..    1193    1466 ..    1185    1468 .. 0.85
   4 !   81.2  19.9   1.5e-26   6.6e-23       4     244 ..    1517    1767 ..    1514    1768 .. 0.93

  Alignments for each domain:
  == domain 1  score: 143.8 bits;  conditional E-value: 1.2e-45
                 HHHHHHHHHHHHHHHHHHCCCSSSS.....HHHHC...HHHHHHHHHHHHHHHHHHHHHHHHHTH.................................. CS
   Ion_trans   3 vfelfilllillncvflaletyfpe.....delek...tileilelvftaiftlemllkilalgl.................................. 59 
                   e fill+i++++v+l++++++p      +  ek   ++++++ +v+ +i+t+e++++i++ g+                                  
  EEA20437.1 345 ATEPFILLVIVVHAVLLTIQSAHPVwthprS--EKwgsQAIDYALFVIFVIYTIELFVRIIVSGFiwnsaeystmdrslgfkkaivergksllslqrqp 441
                 56779**************999998776431..2356799*********************************************************** PP

                 .........................................HHHHHHCHSHHHHHHHHHHHHHHHHHHHHH...HHHHHHHHHHHHGGGGGGHHHCHSH CS
   Ion_trans  60 .........................................likkrYlrdpwnilDflvvlpsllslvlse...esllllsvlrlfrvlrllklisrle 114
                                                          l  + +lr+ +n+lDfl+v+ +++s  l+    +s  ++++++++ +lrll+l+  ++
  EEA20437.1 442 stktksvkfedtqpsylrktvtglqpftdssddprhgsrkrLAYRAFLRHSFNRLDFLAVVSYWISSGLQItgySSKHNIYIFQMLSCLRLLRLLGITD 540
                 **************************************99999999*******************9844444567899********************* PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSCCCC...................................................... CS
   Ion_trans 115 glrtlvtalirsvkdllnvlllllvvlfifaligvqlfkgklrek...................................................... 159
                 g ++++++l++s++ l++v +l+ +++++fa++g+q fk ++r++                                                      
  EEA20437.1 541 GTSVILRSLKKSAPLLVHVGFLIGFFWLLFAIVGIQSFKSSFRRScvwidpegqsnftmndpynviqlcggyldsstgeampwvyanndpspfspkgyl 639
                 *******************************************99*********************999999999999999998887777666665555 PP

                 ...CCSCCSTSSSTTTSSSSSSHHHHHHHHHHHHTTSSHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Ion_trans 160 ...necaktwenpnngntnFdnfftallwlfrlmttegwgdilyatldekskvaliyfvifiilgsflllNlliaviadnfqeltere 244
                    ++ + +++np n++ +Fdn+f++l  +f++m+++ ++d+ly+t+++ +  + ++f++ ++l s++++Nll+avi+++fq ++e++
  EEA20437.1 640 cpqGSMCIEGTNPYNDTMSFDNIFNSLELVFVIMSSNTFTDLLYYTTNSDYLASALFFAVGFVLLSLWMVNLLVAVITSSFQVIREES 727
                 554337789*************************************************************************999875 PP

  == domain 2  score: 83.6 bits;  conditional E-value: 2.7e-27
                 HHHHHHHHHHHHHHHHCCCSSSSHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHCHSHHHHHHHHHHHHHHHHHHHHH....HHHHHHHHHH CS
   Ion_trans   5 elfilllillncvflaletyfpedelektileilelvftaiftlemllkilalgllikkrYlrdpwnilDflvvlpsllslvlse....esllllsvlr 99 
                 +++ + li + +++ +++++ +++++e  ++   e+++t + +le++l++ +      +++ ++  n++D+  ++++++  ++      +++ +l++++
  EEA20437.1 761 SWLWIALIAYDLIVQCMRSATMSQSTE-RFISDTETAVTFVLLLEIILRFAS-DW---RHFHHSKRNLVDLALAVITCIIQIPPIhssgQVYMGLTLFQ 854
                 578899*****************9999.*********************997.66...8************9999999988443343446788888888 PP

                 HHGGGGGGHHHCHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSCCCCCCSCCSTSSSTTTSSS..SSSHHHHHHHHHHHHTTSSHH CS
   Ion_trans 100 lfrvlrllklisrleglrtlvtalirsvkdllnvlllllvvlfifaligvqlfkgklreknecaktwenpnngntn..Fdnfftallwlfrlmttegwg 196
                 ++r++r++ ++s ++    l++ ++r v  lln++l+++++ ++ a+++vqlf g +          +n+n g+++  F ++ +++l++ ++++te+w+
  EEA20437.1 855 ILRIYRIVLAFSVTRD---LIMVVFRNVVGLLNLILFVFLITYLAAIFAVQLFRGVIP--------AQNDNGGTIEmtFFTIYNSFLAMYQILSTENWT 942
                 8888888888888887...777999****************************77776........44444444445599******************* PP

                 HHHHHHHHHS.....HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Ion_trans 197 dilyatldek.....skvaliyfvifiilgsflllNlliaviadnfqe 239
                 +ily  +        s+++  + +i++il+ f++lN++iavi+++f+ 
  EEA20437.1 943 TILYGSTTNTkaygtSWISASFIIIWFILSCFIILNMFIAVIQESFDI 990
                 ****9999889***********************************85 PP

  == domain 3  score: 110.1 bits;  conditional E-value: 2.2e-35
                  HHHHHHHHHHHHHHHHC..CCSSSSHHHHC.HHHHHHHHHHHHHHHHHHHHHHHHHTH.HHHHHHCHSHHHHHHHHHHHHHHHHHHHHH.HHHHHHH CS
   Ion_trans    5 elfilllillncvflal..etyfpedelek.tileilelvftaiftlemllkilalgl.likkrYlrdpwnilDflvvlpsllslvlse.eslllls 96  
                     i+ ++ll+c++ +l  + yf   e++  +++ + +  f ++ft+e+++k++a g+   +  Y+r+ w +lD +v+++ ++ ++ s  ++  + +
  EEA20437.1 1193 YACIVAMVLLACITTPLyqREYFLTREYTPdNWFVWTDAGFAVVFTIEAVIKVIADGFfWTPNAYFRSSWGFLDGVVLITLWINIFTSLfTTGNVSR 1289
                  2334555599999999955555555666668************************999999999*******************99554455688888 PP

                  HHHHHGGGGGGHHHCHSHHHHHHHH.HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSCCCC.............CC........SCCSTSSSTT CS
   Ion_trans   97 vlrlfrvlrllklisrleglrtlvt.alirsvkdllnvlllllvvlfifaligvqlfkgklrek.............ne........caktwenpnn 171 
                  ++ +f+ lr+l+l++ +++ r + +  +i    +++  +++++ +l+ fa+ g++lf g++  +             +e         + + + ++n
  EEA20437.1 1290 IVGAFKALRALRLLNVSDSARDTFHsVIIIGGWKVISAAFVSMSFLIPFAIYGLNLFSGQMISCndgslsgsldgciGEyqsspynwGVLAPRVADN 1386
                  888888888888888888877777736777789*******************************7766666665555115665566666677788** PP

                  TSSSSSSHHHHHHHHHHHHTTSSHHHHHHHHHHHS..........HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Ion_trans  172 gntnFdnfftallwlfrlmttegwgdilyatldek..........skvaliyfvifiilgsflllNlliaviadnfqelt 241 
                  ++++Fdnf+++l+ lf++ ++egw d+ +  ++               + ++fv+f++lg++++l l++ v + n+ e+t
  EEA20437.1 1387 SYYSFDNFGNSLFILFQIVSQEGWIDVQASAMSITgvgqqpqslaAQANGLFFVVFNLLGAVFVLTLFVTVFMRNYTEQT 1466
                  **********************************9*****************************************9997 PP

  == domain 4  score: 81.2 bits;  conditional E-value: 1.5e-26
                  HHHHHHHHHHHHHHHHHCCCSSSSHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHCHSHHHHHHHHHHHHHHHHH..........HHHHH CS
   Ion_trans    4 felfilllillncvflaletyfpedelektileilelvftaiftlemllkilalgllikkrYlrdpwnilDflvvlpsllsl..........vlsee 90  
                  ++ fi+ l++ ++++l+le y+ +d  +  i ++l ++ t +++ ++ ++i++lg     r+ r+ w +  +lvv  +++++          +    
  EEA20437.1 1517 WARFITGLLVFHLLLLTLEWYPYPDLWD-IIRDVLFFILTLFYIADITIRIIGLGW---PRFRRSSWDLYSLLVVPGTFVTVifafifrnvnR---- 1605
                  889********************96555.77788888888****************...***********************88887655333.... PP

                  HHHHHHHHHHHGGGGGGHHHCHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSCCCCCCSCCSTSSSTTTSSSSSSHHHHHHHHH CS
   Ion_trans   91 sllllsvlrlfrvlrllklisrleglrtlvtalirsvkdllnvlllllvvlfifaligvqlfkgklreknecaktwenpnngntnFdnfftallwlf 187 
                   + +l++ +lf v   l +i r + l  l ++ + s+ +++n+l  ++v++++fa+++ q f           ++  +++ +n+nF+++++al+ lf
  EEA20437.1 1606 MNAVLQLNKLFIVSITLLIIPRNNQLDQLFKTAAASLTSIVNLLATWFVLFLVFAIAMTQTF---------GLTKFGGHETNNINFRDVPNALILLF 1693
                  69************************************************************.........555678888999************** PP

                  HHHTTSSHHHHHHHHHHHS.................HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Ion_trans  188 rlmttegwgdilyatldek.................skvaliyfvifiilgsflllNlliaviadnfqeltere 244 
                  r+  +egw++++ ++   +                 + +a  +f+++++++++l+++l++ +i ++f+++++r+
  EEA20437.1 1694 RTSAGEGWNQLMEDFATMErpyctlndeflksdcgsQGWARGLFIAWNVISMYLFVSLFVSLIYESFSYVYQRS 1767
                  **************9999999***************************************************97 PP

>> GPHH  Voltage-dependent L-type calcium channel, IQ-associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0      0.86   3.9e+03      38      49 ..    1155    1166 ..    1152    1167 .. 0.84
   2 !   18.4   0.0     3e-07    0.0013       1      30 [.    1782    1811 ..    1782    1812 .. 0.94

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.86
        GPHH   38 kcPsrvaykrlv 49  
                  k P r+a++r+v
  EEA20437.1 1155 KNPIRRACQRMV 1166
                  6799******97 PP

  == domain 2  score: 18.4 bits;  conditional E-value: 3e-07
        GPHH    1 eFvrvWaeyDPeAtgrikvqdmyellrrls 30  
                  +F+++Wa++DP+ +g+i  q+   ll +ls
  EEA20437.1 1782 RFKEAWANFDPHGSGFITKQQFPRLLGELS 1811
                  7**********************9999876 PP

>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   8.6e-06     0.038       2      26 ..    1783    1807 ..    1782    1810 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 8.6e-06
                  HHHHHHHHTTTSSSEEEHHHHHHHH CS
   EF-hand_1    2 lkeiFrefDkDgdGkIdfeEfkell 26  
                  +ke+++ fD  g+G+I++++f +ll
  EEA20437.1 1783 FKEAWANFDPHGSGFITKQQFPRLL 1807
                  89******************97776 PP

>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   1.7e-05     0.077       1      27 [.    1782    1808 ..    1782    1812 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 1.7e-05
   EF-hand_6    1 elreaFklfDkdgdGkidaeElrkalr 27  
                  +++ea+  fD  g+G+i+++++ ++l 
  EEA20437.1 1782 RFKEAWANFDPHGSGFITKQQFPRLLG 1808
                  699*******************99886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2116 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1045  (0.0582855); expected 358.6 (0.02)
Passed bias filter:                      460  (0.0256568); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.24u 0.36s 00:00:01.60 Elapsed: 00:00:00.57
# Mc/sec: 11147.26
//
Query:       EEA20438.1  [L=397]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      9e-27   93.5   0.0    1.4e-26   92.8   0.0    1.3  1  Proteasom_Rpn13  Proteasome complex subunit Rpn13 ubiquitin r
    6.7e-10   39.1   1.1    1.3e-08   34.9   1.1    2.4  1  RPN13_C          UCH-binding domain


Domain annotation for each model (and alignments):
>> Proteasom_Rpn13  Proteasome complex subunit Rpn13 ubiquitin receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.8   0.0   1.6e-30   1.4e-26       1      86 []      13     107 ..      13     107 .. 0.89

  Alignments for each domain:
  == domain 1  score: 92.8 bits;  conditional E-value: 1.6e-30
  Proteasom_Rpn13   1 Gkceld..ektkkvkpdprkGliylykeeeellhfkWkdrek.tgeaeddlilipgdasfkk....veqc.....ktgRvyvLkfksssqrlfF 82 
                      G c+ld  +++ +vkp++++G+iyly +e++l+hf+W++r++  +++e dl+++p+d +f++             ++gR+yvLkf+sssqr++F
       EEA20438.1  13 GICDLDtsTSPPQVKPKSTPGYIYLY-SEDDLIHFCWRPRSAaLTDPELDLVMVPSDGTFTPyrstQ--EntrapTNGRIYVLKFSSSSQRYLF 103
                      889999766888**************.5666************9******************76652..145778******************* PP

  Proteasom_Rpn13  83 WlQd 86 
                      WlQ+
       EEA20438.1 104 WLQS 107
                      ***6 PP

>> RPN13_C  UCH-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.9   1.1   1.5e-12   1.3e-08       5      95 ..     227     353 ..     223     376 .. 0.78

  Alignments for each domain:
  == domain 1  score: 34.9 bits;  conditional E-value: 1.5e-12
     RPN13_C   5 aslqqakaaaq.....epevsLsdiltpealspll..sdpevveeLashLPe..............egeate...................eelretlr 63 
                 +slq+ ++ aq        ++L+d+l+p  + p++  +d++ v++L+++LP+              +                        + lr++lr
  EEA20438.1 227 NSLQGGNQPAQsqseeYLYTTLADLLSPPSTIPMIesADDNQVDNLLNFLPPallllaqniddipaS----DinaetaqavllsldleqkrDILRRVLR 321
                 555544444333333344579*****9999999997556669*************999888766550....1444556678888888888799****** PP

     RPN13_C  64 SPqfrqalsslsqALqsgqlgpvlsqlgLdee 95 
                 SPqf q+l sl+ A+++g+l ++ ++l ++ e
  EEA20438.1 322 SPQFTQSLGSLTVAIRDGGLPSISEALKVPVE 353
                 **************************999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       338  (0.0188521); expected 358.6 (0.02)
Passed bias filter:                      299  (0.0166769); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.47
# Mc/sec: 2550.77
//
Query:       EEA20439.1  [L=199]
Description: 60S ribosomal protein L6 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.5e-39  135.0   0.3    1.5e-39  135.0   0.3    1.4  2  Ribosomal_L6e    Ribosomal protein L6e
  ------ inclusion threshold ------
       0.04   13.4   0.4      0.055   13.0   0.4    1.2  1  ORC5_C           Origin recognition complex (ORC) subunit 5 C
       0.12   11.7   0.2       0.19   11.1   0.2    1.2  1  GNAT_acetyltr_2  GNAT acetyltransferase 2


Domain annotation for each model (and alignments):
>> Ribosomal_L6e  Ribosomal protein L6e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.1       1.8   1.1e+04      68      72 ..      21      25 ..       4      43 .. 0.46
   2 !  135.0   0.3   2.5e-43   1.5e-39       1     111 []      88     199 .]      88     199 .] 0.95

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 1.8
  Ribosomal_L6e 68 erkad 72
                   +++++
     EEA20439.1 21 QKAQK 25
                   22222 PP

  == domain 2  score: 135.0 bits;  conditional E-value: 2.5e-43
  Ribosomal_L6e   1 lNgvPLrRvnqryVIatstkvdlsgvd.ekipeklndeyFkkekkkkkkkkkeeelf..eekkekkelseerkadqkavDkallaaikkekllkkY 93 
                    +NgvPLrRvn+ryVIats kvdlsg+d +++++    +yF+kek+++kk  +ee++f   ek ekk+++++r+adqka+D++lla+ikke+ll++Y
     EEA20439.1  88 INGVPLRRVNARYVIATSGKVDLSGIDaATLEKVAASDYFTKEKAQEKK--TEEAFFkqGEKPEKKKITSARAADQKAIDQSLLATIKKEHLLASY 181
                    7**************************989999999*******877775..999***88888999******************************* PP

  Ribosomal_L6e  94 LkskFsLrkgdyphelkF 111
                    L+++FsLrkgd+phe+k+
     EEA20439.1 182 LATSFSLRKGDKPHEMKW 199
                    *****************8 PP

>> ORC5_C  Origin recognition complex (ORC) subunit 5 C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.4   9.2e-06     0.055      83     146 ..     116     185 ..      92     193 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 9.2e-06
      ORC5_C  83 srl.laanralfrdqgesalaeelv.....ektaasssassasskssssklpeLpylaklLLiAAYLASy 146
                  +l  +a++++f++++++++++e++     ek ++++ +s +++ +++ ++  L+++ k  L+A+YLA  
  EEA20439.1 116 ATLeKVAASDYFTKEKAQEKKTEEAffkqgEKPEKKKITSARAADQKAIDQSLLATIKKEHLLASYLATS 185
                 44467788999999777777666669998855555555555566777788899***************64 PP

>> GNAT_acetyltr_2  GNAT acetyltransferase 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.2   3.2e-05      0.19     101     189 ..     102     188 ..      94     191 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 3.2e-05
  GNAT_acetyltr_2 101 iAvhpelqkmGYGsralellekyyegklssleeeeekeeeeeeekeeeeeklsleeeklkprkelpplllklseekpekldylgvsfGl 189
                      iA+  ++   G  +++le++ +      ++++++e+k+ee   ++ e+ ek+++++++  ++k + + ll + +++     yl++sf l
       EEA20439.1 102 IATSGKVDLSGIDAATLEKVAASDYF--TKEKAQEKKTEEAFFKQGEKPEKKKITSARAADQKAIDQSLLATIKKEHLLASYLATSFSL 188
                      88888999999999999998754333..3333333333333333334455788899999999999999999999999999*******77 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (199 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       953  (0.0531541); expected 358.6 (0.02)
Passed bias filter:                      465  (0.0259356); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1329.72
//
Query:       EEA20440.1  [L=322]
Description: Sterol desaturase family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.4e-18   65.4   3.7    6.4e-18   65.4   3.7    1.7  2  FA_hydroxylase  Fatty acid hydroxylase superfamily


Domain annotation for each model (and alignments):
>> FA_hydroxylase  Fatty acid hydroxylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.3      0.26   4.7e+03      74      74 ..      30      30 ..       3      68 .. 0.54
   2 !   65.4   3.7   3.6e-22   6.4e-18       2     132 ..     134     265 ..     133     266 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 0.26
  FA_hydroxylase 74 l 74
                    +
      EEA20440.1 30 F 30
                    2 PP

  == domain 2  score: 65.4 bits;  conditional E-value: 3.6e-22
  FA_hydroxylase   2 llallledfveYwvHr.llHrvkllwrrlHkv.HHsseaptalaalrahpleallla.llllllllllg.plsalllvlvlaallelliHsglhv 92 
                     + ++++ ++++Y++Hr +lH+ +l ++rlH++ +H  +ap +l+a++ hpl +ll++ l+++++++l+  ++ +++++l l  l e+++Hsg  +
      EEA20440.1 134 VRGFIVREIMNYTIHRfILHNDRLRVNRLHETwYHGLRAPWPLTAHYDHPLCYLLWKfLPVYVPAALFRfHMITYMVFLGLVSLEETWTHSG--Y 226
                     5689*****************9997788***99************************9999999999999**********************..6 PP

  FA_hydroxylase  93 slgwllerllatpraHrlHHskneegnfgvllslwDrlfg 132
                     s  +l+  l   +r  ++H  +  +gn+g   +++D+l g
      EEA20440.1 227 SSMPLGFVLGGIARRTEMHVISGGDGNYGA-WGVLDWLGG 265
                     66666555688899999999**********.79****987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (322 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       579  (0.032294); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.47
# Mc/sec: 2040.52
//
Query:       EEA20441.1  [L=305]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-13   50.6   0.2      2e-12   47.2   0.2    2.3  2  DUF3425   Domain of unknown function (DUF3425)
     0.0033   17.5  19.1       0.15   12.2  19.2    2.2  1  bZIP_1    bZIP transcription factor
  ------ inclusion threshold ------
       0.15   10.5   0.0       0.15   10.5   0.0    1.1  1  LCD1      DNA damage checkpoint protein


Domain annotation for each model (and alignments):
>> DUF3425  Domain of unknown function (DUF3425)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0     0.082   4.9e+02      47      80 ..     114     144 ..      39     167 .. 0.82
   2 !   47.2   0.2   3.3e-16     2e-12       5     118 ..     183     284 ..     180     289 .. 0.75

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.082
     DUF3425  47 drllrafqeeeidedeffrdvvstlivWsieeee 80 
                 d ++r  +  e++ de++++  + + +W    ++
  EEA20441.1 114 DDIVR--SPSETQGDELYQEQHKYKNCWHR-SRQ 144
                 55555..33347789999999999999963.333 PP

  == domain 2  score: 47.2 bits;  conditional E-value: 3.3e-16
     DUF3425   5 rfpispseeaveklpenlrPtelQlriaHpveidvlpwpelRdrllr.afqeeeidedeffrdvvs.........tlivWsieeeeletaeissaelsa 93 
                 ++++s+ ++   +lp+ l+Pt lQl+++H+++id++p p+lRd l++  f       + f+ +v++          l  W                   
  EEA20441.1 183 QLHLSTLAAIGPSLPPALQPTLLQLQTPHHAYIDLIPSPRLRDSLIQaGFA----VANSFLTEVCTfvyetedlgQLTIWG------------------ 259
                 6666666667778**********************************4222....33444444432222244555666775.................. PP

     DUF3425  94 gdvtdlegWelkesFfrkYpylvdg 118
                  d  ++ +We++e+ ++ +p+l+ +
  EEA20441.1 260 RDYLNVISWEFSEQVLKAWPNLLME 284
                 6899999************999876 PP

>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.2  19.2   2.5e-05      0.15       4      61 ..       8      69 ..       5      73 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2.5e-05
                XXXXXXX--HHHHHHHHHHHHHHHHHHHHH....HHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  4 lKrekrkqkNReaArrsRqRKqaeieeLer....rvkaLekeNksLkseleelkkevekLks 61
                 K ek+++ NR a+r +RqR+++  + Ler    r+++  +e + L+  +e+l+ e+  Lks
  EEA20441.1  8 SKAEKKREYNRNAQRLFRQRRKEHLKSLERaekeRSSTHAEEVELLRRDMEQLRAENRALKS 69
                699*************************9733335555566666666666666666666666 PP

>> LCD1  DNA damage checkpoint protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   2.6e-05      0.15       9      60 ..      24      75 ..      18     217 .. 0.92

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 2.6e-05
                HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHTTTT CS
        LCD1  9 LeqekekeleklknskkqlkesheeelekLkkevqkleDekkFlenElrsls 60
                + q+++++l++l++ +k+  ++h ee+e L+ ++++l  e++ l+  l+ +s
  EEA20441.1 24 FRQRRKEHLKSLERAEKERSSTHAEEVELLRRDMEQLRAENRALKSSLKLSS 75
                5688899999*******************************99998887666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (305 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1385  (0.0772491); expected 358.6 (0.02)
Passed bias filter:                      688  (0.0383736); expected 358.6 (0.02)
Passed Vit filter:                        88  (0.00490825); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 2044.69
//
Query:       EEA20442.1  [L=523]
Description: RNA export mediator Gle1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.7e-46  157.8   0.0    7.2e-46  156.4   0.0    1.7  2  GLE1        GLE1-like protein
  ------ inclusion threshold ------
       0.97    8.1  51.6        1.3    7.7  51.6    1.1  1  Caldesmon   Caldesmon
        4.1    5.4  19.6        5.2    5.1  19.6    1.1  1  Hid1        High-temperature-induced dauer-formation protein
        7.3    6.4   6.2         12    5.7   6.2    1.3  1  Velvet      Velvet factor


Domain annotation for each model (and alignments):
>> GLE1  GLE1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.4      0.49   2.2e+03     141     168 ..     186     214 ..     180     214 .. 0.80
   2 !  156.4   0.0   1.6e-49   7.2e-46       3     248 ..     219     487 ..     217     490 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.49
        GLE1 141 qsteeyrkrlGykrs.ddgkletedkyle 168
                 +++e+ r++lG  +  ++++le+++kyle
  EEA20442.1 186 EEEEKKRRTLGGAQGvTQEELEEQEKYLE 214
                 66888899999776668899*******86 PP

  == domain 2  score: 156.4 bits;  conditional E-value: 1.6e-49
        GLE1   3 ikqikknlleqvkedkelkkllgdlkrkInpkvgQltnss..eqlkkitkelkellesgkpvkvadk........p............elaykyllnfl 79 
                 +k+++k ++++ k++++lk+++gd++r I++ +gQl++ +  +  k  ++e++e+l +++++++           p            ++++ ylln++
  EEA20442.1 219 LKELRKFVVAEGKKNPTLKSTIGDYRRGITKCIGQLREGQgtAANKGQVNEIREILRKSQEIPIPCDarrffvnaPeiaslpedkaqvSAVFVYLLNIF 317
                 68999***********************************977777899*******6666654432235777766155556677777899********* PP

        GLE1  80 AkalvsqaetevsakpeaAfplArvavgllseh......pelgdlllArlvkkCpylvpfypakkegqsteeyrkrlGykrs.ddgkletedkyleRms 171
                  ka+v q  +e+ +k e+A pl++v+++++s        + + d+++A+++  Cp l++f     ++++t +++++lG+kr    g + +++++ +Rm 
  EEA20442.1 318 VKAVVLQLINEAGIKLEYAEPLGVVVAQIFSAEqfcfqgHAFSDVFWAKYRASCPALWGF----YGDEKTVAGKQALGWKRIePGGPFLSDTDHRQRMV 412
                 *******************************9768*************************....89999***********976888************* PP

        GLE1 172 GiirlYaaiiqtelsksskenphppgleiaWrwlarilnlpleplsnitatllaafLevagnrllkaYgkqfqKlle 248
                 G+  ++aa++++++ k+s++np+p+ +   W+ ++r++  p+++l++++++ll+a+L  +++r++ ++g ++ +ll+
  EEA20442.1 413 GLGGGFAAVTLRNFGKTSRKNPFPNYIF--WKTVSRMVSIPPNELQETHFYLLYAMLRFSAERVIGFWGHAGLALLR 487
                 *****************99999999999..******************************************99997 PP

>> Caldesmon  Caldesmon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7  51.6   0.00029       1.3      27     205 ..      45     224 ..      26     280 .. 0.47

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00029
   Caldesmon  27 epssqsdslvetnshrsevteeaselkssgeegddedqalldrlakreerrqrrlkea.lerqkeldaeaaeaseerslaeekeeaeeeek....ssrr 120
                 ++ ++++++++   ++   +  +++  ++ ++  + +  l+++l+ +ee+ +rr++e+  +rq e++  ++e +e r++a+ k+e+e +++    ++++
  EEA20442.1  45 QAQEEEEDEIDRAHQEFYYAAIEKTYDYYDGHRREAEIVLQEHLREEEEKERRRQEEEeRRRQAEKERLERERKE-REEAARKREEEARREaeriAREE 142
                 233333444444555566677777777788888888888888877776666666655424455555555555444.22222222222222200002222 PP

   Caldesmon 121 keryrdeeeeeeeteekekereekkqaeskeeeeeekaeaeeeaeeeeeekkvdes...edkevseelkde............eskqvleekkaieesk 204
                 +er ++ e e +    k  e+e++ +++++e ee+e+++++e ++ eeeekk   +    +  ++eel+++                           +
  EEA20442.1 143 EERRKKAEAEAKA--IKAAEEEKT-RRQKEEAEEKERQRQAELQRAEEEEKK-RRTlggAQGVTQEELEEQekylelhkylkeL--------------R 223
                 2222222222222..222222222.233333333333333333333333333.3334554556666666662222222223322..............2 PP

   Caldesmon 205 k 205
                 k
  EEA20442.1 224 K 224
                 2 PP

>> Hid1  High-temperature-induced dauer-formation protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1  19.6    0.0011       5.2     588     706 ..      78     213 ..      12     227 .. 0.46

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0011
        Hid1 588 e..............sarldsideeeeenssessrieesrsesrsps...lsevpelksslaitddeskaereksatessssqavs..qlremsekara 667
                 +              +++  + +eee++++ e++r e++r+e +++    ++e +++ + +a +++e +++ e +a+ +++    +  ++r+ +e+a++
  EEA20442.1  78 ReaeivlqehlreeeEKERRRQEEEERRRQAEKERLERERKEREEAArkrEEEARREAERIAREEEERRKKAEAEAKAIKAA---EeeKTRRQKEEAEE 173
                 0443344333333222222222222222233333333322222222200022222233333333333333333333333333...12345566666666 PP

        Hid1 668 kesaesteesrqesatskksp.sgmsqsaeekftptsewl 706
                 ke + + e +r+e++++k +   g + +++e++ +++++l
  EEA20442.1 174 KERQRQAELQRAEEEEKKRRTlGGAQGVTQEELEEQEKYL 213
                 6666666666655555544430334445555666655555 PP

>> Velvet  Velvet factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   6.2    0.0027        12      39     159 ..      47     207 ..      29     220 .. 0.51

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0027
                 TT-SB--GGG---TTEEEEEEEEETT...SSSB--EE...........................--.---------.-------------......... CS
      Velvet  39 etnsevdveeldssffvvtvdLwsed...gtkevnlv...........................kssssasssisseasssssqsseess......... 98 
                 ++++e ++++++++f+ + ++ + +     ++e+++v                           +                        +         
  EEA20442.1  47 QEEEEDEIDRAHQEFYYAAIEKTYDYydgHRREAEIVlqehlreeeekerrrqeeeerrrqaekE------------------------Rlererkere 121
                 66677777777777777777665522444556666666665544444433322222222222210........................1122111112 PP

                 .......................--------------------------..........................-------------------EESEE CS
      Velvet  99 .......................sspksqassaessapsssaapsaqee..........................kekkeatlssssnqasskltrnLi 148
                                                                 +                          +++++++++ +  ++++k  r+L 
  EEA20442.1 122 eaarkreeearreaeriareeeeR------------------------RkkaeaeakaikaaeeektrrqkeeaeEKERQRQAELQRAEEEEKKRRTLG 196
                 222211122222222222222221........................022333444444444444455555554666666667777777899999999 PP

                 E--EEE-EEEE CS
      Velvet 149 Gslvasafrlk 159
                 G + ++   l+
  EEA20442.1 197 GAQGVTQEELE 207
                 98877766555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (523 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3168  (0.176697); expected 358.6 (0.02)
Passed bias filter:                      963  (0.0537119); expected 358.6 (0.02)
Passed Vit filter:                       402  (0.0224218); expected 17.9 (0.001)
Passed Fwd filter:                       123  (0.00686039); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.69u 0.41s 00:00:02.10 Elapsed: 00:00:00.59
# Mc/sec: 2660.57
//
Query:       EEA20443.1  [L=523]
Description: RNA export mediator Gle1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.7e-46  157.8   0.0    7.2e-46  156.4   0.0    1.7  2  GLE1        GLE1-like protein
  ------ inclusion threshold ------
       0.97    8.1  51.6        1.3    7.7  51.6    1.1  1  Caldesmon   Caldesmon
        4.1    5.4  19.6        5.2    5.1  19.6    1.1  1  Hid1        High-temperature-induced dauer-formation protein
        7.3    6.4   6.2         12    5.7   6.2    1.3  1  Velvet      Velvet factor


Domain annotation for each model (and alignments):
>> GLE1  GLE1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.4      0.49   2.2e+03     141     168 ..     186     214 ..     180     214 .. 0.80
   2 !  156.4   0.0   1.6e-49   7.2e-46       3     248 ..     219     487 ..     217     490 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.49
        GLE1 141 qsteeyrkrlGykrs.ddgkletedkyle 168
                 +++e+ r++lG  +  ++++le+++kyle
  EEA20443.1 186 EEEEKKRRTLGGAQGvTQEELEEQEKYLE 214
                 66888899999776668899*******86 PP

  == domain 2  score: 156.4 bits;  conditional E-value: 1.6e-49
        GLE1   3 ikqikknlleqvkedkelkkllgdlkrkInpkvgQltnss..eqlkkitkelkellesgkpvkvadk........p............elaykyllnfl 79 
                 +k+++k ++++ k++++lk+++gd++r I++ +gQl++ +  +  k  ++e++e+l +++++++           p            ++++ ylln++
  EEA20443.1 219 LKELRKFVVAEGKKNPTLKSTIGDYRRGITKCIGQLREGQgtAANKGQVNEIREILRKSQEIPIPCDarrffvnaPeiaslpedkaqvSAVFVYLLNIF 317
                 68999***********************************977777899*******6666654432235777766155556677777899********* PP

        GLE1  80 AkalvsqaetevsakpeaAfplArvavgllseh......pelgdlllArlvkkCpylvpfypakkegqsteeyrkrlGykrs.ddgkletedkyleRms 171
                  ka+v q  +e+ +k e+A pl++v+++++s        + + d+++A+++  Cp l++f     ++++t +++++lG+kr    g + +++++ +Rm 
  EEA20443.1 318 VKAVVLQLINEAGIKLEYAEPLGVVVAQIFSAEqfcfqgHAFSDVFWAKYRASCPALWGF----YGDEKTVAGKQALGWKRIePGGPFLSDTDHRQRMV 412
                 *******************************9768*************************....89999***********976888************* PP

        GLE1 172 GiirlYaaiiqtelsksskenphppgleiaWrwlarilnlpleplsnitatllaafLevagnrllkaYgkqfqKlle 248
                 G+  ++aa++++++ k+s++np+p+ +   W+ ++r++  p+++l++++++ll+a+L  +++r++ ++g ++ +ll+
  EEA20443.1 413 GLGGGFAAVTLRNFGKTSRKNPFPNYIF--WKTVSRMVSIPPNELQETHFYLLYAMLRFSAERVIGFWGHAGLALLR 487
                 *****************99999999999..******************************************99997 PP

>> Caldesmon  Caldesmon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7  51.6   0.00029       1.3      27     205 ..      45     224 ..      26     280 .. 0.47

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00029
   Caldesmon  27 epssqsdslvetnshrsevteeaselkssgeegddedqalldrlakreerrqrrlkea.lerqkeldaeaaeaseerslaeekeeaeeeek....ssrr 120
                 ++ ++++++++   ++   +  +++  ++ ++  + +  l+++l+ +ee+ +rr++e+  +rq e++  ++e +e r++a+ k+e+e +++    ++++
  EEA20443.1  45 QAQEEEEDEIDRAHQEFYYAAIEKTYDYYDGHRREAEIVLQEHLREEEEKERRRQEEEeRRRQAEKERLERERKE-REEAARKREEEARREaeriAREE 142
                 233333444444555566677777777788888888888888877776666666655424455555555555444.22222222222222200002222 PP

   Caldesmon 121 keryrdeeeeeeeteekekereekkqaeskeeeeeekaeaeeeaeeeeeekkvdes...edkevseelkde............eskqvleekkaieesk 204
                 +er ++ e e +    k  e+e++ +++++e ee+e+++++e ++ eeeekk   +    +  ++eel+++                           +
  EEA20443.1 143 EERRKKAEAEAKA--IKAAEEEKT-RRQKEEAEEKERQRQAELQRAEEEEKK-RRTlggAQGVTQEELEEQekylelhkylkeL--------------R 223
                 2222222222222..222222222.233333333333333333333333333.3334554556666666662222222223322..............2 PP

   Caldesmon 205 k 205
                 k
  EEA20443.1 224 K 224
                 2 PP

>> Hid1  High-temperature-induced dauer-formation protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1  19.6    0.0011       5.2     588     706 ..      78     213 ..      12     227 .. 0.46

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0011
        Hid1 588 e..............sarldsideeeeenssessrieesrsesrsps...lsevpelksslaitddeskaereksatessssqavs..qlremsekara 667
                 +              +++  + +eee++++ e++r e++r+e +++    ++e +++ + +a +++e +++ e +a+ +++    +  ++r+ +e+a++
  EEA20443.1  78 ReaeivlqehlreeeEKERRRQEEEERRRQAEKERLERERKEREEAArkrEEEARREAERIAREEEERRKKAEAEAKAIKAA---EeeKTRRQKEEAEE 173
                 0443344333333222222222222222233333333322222222200022222233333333333333333333333333...12345566666666 PP

        Hid1 668 kesaesteesrqesatskksp.sgmsqsaeekftptsewl 706
                 ke + + e +r+e++++k +   g + +++e++ +++++l
  EEA20443.1 174 KERQRQAELQRAEEEEKKRRTlGGAQGVTQEELEEQEKYL 213
                 6666666666655555544430334445555666655555 PP

>> Velvet  Velvet factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   6.2    0.0027        12      39     159 ..      47     207 ..      29     220 .. 0.51

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0027
                 TT-SB--GGG---TTEEEEEEEEETT...SSSB--EE...........................--.---------.-------------......... CS
      Velvet  39 etnsevdveeldssffvvtvdLwsed...gtkevnlv...........................kssssasssisseasssssqsseess......... 98 
                 ++++e ++++++++f+ + ++ + +     ++e+++v                           +                        +         
  EEA20443.1  47 QEEEEDEIDRAHQEFYYAAIEKTYDYydgHRREAEIVlqehlreeeekerrrqeeeerrrqaekE------------------------Rlererkere 121
                 66677777777777777777665522444556666666665544444433322222222222210........................1122111112 PP

                 .......................--------------------------..........................-------------------EESEE CS
      Velvet  99 .......................sspksqassaessapsssaapsaqee..........................kekkeatlssssnqasskltrnLi 148
                                                                 +                          +++++++++ +  ++++k  r+L 
  EEA20443.1 122 eaarkreeearreaeriareeeeR------------------------RkkaeaeakaikaaeeektrrqkeeaeEKERQRQAELQRAEEEEKKRRTLG 196
                 222211122222222222222221........................022333444444444444455555554666666667777777899999999 PP

                 E--EEE-EEEE CS
      Velvet 149 Gslvasafrlk 159
                 G + ++   l+
  EEA20443.1 197 GAQGVTQEELE 207
                 98877766555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (523 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3168  (0.176697); expected 358.6 (0.02)
Passed bias filter:                      963  (0.0537119); expected 358.6 (0.02)
Passed Vit filter:                       402  (0.0224218); expected 17.9 (0.001)
Passed Fwd filter:                       123  (0.00686039); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.75u 0.40s 00:00:02.15 Elapsed: 00:00:00.60
# Mc/sec: 2609.41
//
Query:       EEA20444.1  [L=1339]
Description: cell wall biogenesis protein phosphatase Ssd1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.4e-89  299.4   0.1    7.7e-89  298.2   0.0    1.7  2  RNB            RNB domain
      2e-26   91.8   0.1    7.3e-26   90.0   0.0    2.1  2  OB_Dis3        Dis3-like cold-shock domain 2 (CSD2)
    1.5e-25   89.3   0.0    4.9e-25   87.7   0.0    2.0  1  Dis3l2_C_term  DIS3-like exonuclease 2 C terminal
    8.7e-05   22.6   0.0      0.028   14.6   0.0    2.8  2  CSD2           Cold shock domain
    9.9e-05   22.1   0.0    0.00022   20.9   0.0    1.5  1  Rrp44_CSD1     Rrp44-like cold shock domain


Domain annotation for each model (and alignments):
>> RNB  RNB domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.3       1.8   6.6e+03     228     275 ..     353     399 ..     348     414 .. 0.55
   2 !  298.2   0.0   2.2e-92   7.7e-89       1     325 [.     720    1052 ..     720    1053 .. 0.98

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 1.8
                 xxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         RNB 228 epsnekledliklakklglk.lednsskknlqeslekleeeeaeqllse 275
                 ++++ +l++l+ + ++ +l+ l+ ++++   q++  + ++++ ++l+ +
  EEA20444.1 353 QLNPLQLAQLQAMQQNGQLNgLQASQHA--PQQLSAQQQQQQRKTLFTP 399
                 5566778888888887777742222222..2222223333333444444 PP

  == domain 2  score: 298.2 bits;  conditional E-value: 2.2e-92
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         RNB    1 RkdlrdllvitIdpedakdlDdAisieklpngnyelgVhIADvshyvkegspldkearkratsvyLpekvvpMLPqelsedlcSLnpgedrlalsvl 97  
                  R+dlrd +++tIdp ++k+lDdAi+i+kl +g++e+g+h+ADv+h+vk +s +d+ea+kr+t v L  +vv+MLP++ls+++cSL pg++rl++sv+
  EEA20444.1  720 RRDLRDETTFTIDPTGTKELDDAIHIKKLGDGKVEIGIHVADVAHFVKANSLVDREAKKRGTGVHLMTRVVNMLPPRLSNEVCSLVPGQERLTVSVV 816 
                  9************************************************************************************************ PP

                  xxxxxx.xxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         RNB   98 idvdek.gev.lsveiylsvIkskarltydevqdlleqkdeke.ekktaedLellyelakalrkkRlkkgalefdspeikllldedkgnrielkvee 191 
                  ++vd   g v ++v+i++svIks+ +l+yd+v+ ++++ + +  e+ +a+d++ll  ++ ++++ R  + ++++      ++ld+ ++ ++el++ +
  EEA20444.1  817 FQVDTVtGAVdDDVWIGKSVIKSSGKLSYDDVNSAINGGTGSPlEGVNADDIRLLGAITTKFKEARFGNRTTNIPAMRLIYQLDD-ENMPVELNIFD 912 
                  ****999***9999************************999999999***************************99999999*99.888******** PP

                  xxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         RNB  192 etkahslveelmllANelvArfl.seleipailriheepsnekledliklakklglklednsskknlqeslekleeeeaeqllselllrllkeakys 287 
                  ++ ah+++eel + AN  vAr+l ++ +++a+lr++  p++ +l+ +++  ++lg++ + +ss  +lq sl k+++ + ++ ++ +l++++++aky 
  EEA20444.1  913 SSPAHEVIEELNYKANFFVARKLfAAMPEKAFLRRQAVPNPRRLQAFVDRVNRLGYDIDPSSSG-SLQASLFKVQDVDLRKGMETILIKAMQRAKYY 1008
                  ***********************9*********************************9888888.9******************************* PP

                  xxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         RNB  288 sep......vgHfgLaleeYthfTSPirRYpDlvvhrllkalla 325 
                  +         +H++L+l+ Y+hfTSP rRY+D++vhr+l a+l+
  EEA20444.1 1009 VAGnvteaqRQHYALNLPLYAHFTSPTRRYADVIVHRQLDAVLS 1052
                  8888999999*******************************997 PP

>> OB_Dis3  Dis3-like cold-shock domain 2 (CSD2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.0   0.0     2e-29   7.3e-26       2      77 .]     613     688 ..     612     688 .. 0.98
   2 ?   -2.9   0.0       2.1   7.4e+03      12      33 ..    1271    1292 ..    1266    1294 .. 0.85

  Alignments for each domain:
  == domain 1  score: 90.0 bits;  conditional E-value: 2e-29
                 EEE--SSTTS--EEEETTSSTTTHHHHTTTTTT--EEEEE----TT-SS-EEEEEEE-HHHHHHHHHHHHHHHHTT CS
     OB_Dis3   2 vlfkPldkrlPriliptkelpeeflenpeelegklfvvkidsWsetsryPlGeivksLGeagdieaeteaiLleng 77 
                 v+fkP+dkr+P i ipt+++p +f+e+++++++ +fv++i++W++ts +P+G++v++LGe+gd+++et+a+L +n+
  EEA20444.1 613 VWFKPTDKRVPLIAIPTEQAPRDFVEKHQDYANRIFVACIKRWPITSLHPFGTLVEQLGEMGDLKVETDALLRDNN 688
                 9***********************************************************************9996 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 2.1
                  --EEEETTSSTTTHHHHTTTTT CS
     OB_Dis3   12 Priliptkelpeeflenpeele 33  
                  P+i i  +e pe  ++++e++ 
  EEA20444.1 1271 PKIAISASETPEAKMTDKEKYL 1292
                  99********999888888875 PP

>> Dis3l2_C_term  DIS3-like exonuclease 2 C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.7   0.0   1.4e-28   4.9e-25       1      84 [.    1104    1188 ..    1104    1191 .. 0.92

  Alignments for each domain:
  == domain 1  score: 87.7 bits;  conditional E-value: 1.4e-28
  Dis3l2_C_term    1 GpleekavVvnVldssfDVlileyGlekRVyldklplkefefdk.tkvLtLyWkkdvpeaevvqeeekfssvvkvvlkseeeslk 84  
                     G+l+++++V++V++s+fDVl++e+G+ekRV++d+lplk++e++k t+vL+LyW+k+vp++++++e+e+++ +  +  +++  +++
     EEA20444.1 1104 GDLISEGIVLCVYESAFDVLLPEFGFEKRVHCDQLPLKKAEYRKdTRVLELYWEKGVPSSAYIPEDERPNASSSRAAHAAAAAQE 1188
                     99****************************************976999********************99988887777666665 PP

>> CSD2  Cold shock domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.9   0.0    0.0085        30       9      36 ..     437     465 ..     434     475 .. 0.83
   2 !   14.6   0.0   7.7e-06     0.028       3      70 ..     616     690 ..     614     695 .. 0.69

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.0085
        CSD2   9 lkqdifip.keklkgakdGdkVvveitey 36 
                 l  difi   ++++ a +Gd V ve+++ 
  EEA20444.1 437 LDADIFICgSKDRNRALEGDFVAVELLDV 465
                 567999875788999**********9875 PP

  == domain 2  score: 14.6 bits;  conditional E-value: 7.7e-06
        CSD2   3 vpddkrlkqdifipkeklk.gakd......GdkVvveiteyp.dkknpeGevievLGkkgdpgveilsilakhglp 70 
                 +p dkr++  i ip e++  ++++      + + v+ i+++p +  +p G+ +e LG+ gd +ve ++ l+ +++ 
  EEA20444.1 616 KPTDKRVP-LIAIPTEQAPrDFVEkhqdyaNRIFVACIKRWPiTSLHPFGTLVEQLGEMGDLKVETDALLRDNNFA 690
                 56666666.3666644333122221111225667888*****76667************************99985 PP

>> Rrp44_CSD1  Rrp44-like cold shock domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.0   6.2e-08   0.00022       5      76 ..     398     469 ..     395     509 .. 0.80

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 6.2e-08
                 -----HHHHHHHHHTTSEEEEEEEEESSBTTEEEEE-SSSSS-EEEESHHHHTS--TT-EEEEEE--GGG-B CS
  Rrp44_CSD1   5 peyystarvmgglkngvlyqgniqiseynflegsvslprfskpvlivgqknlnrafngdqvivellpqsewk 76 
                   y   a +   l ng l  g +++ + n  +  v+   +   ++i g k+ nra++gd v vell   e  
  EEA20444.1 398 TPYLPQANLPALLSNGQLVAGILRVNKKNRSDAYVTCTELDADIFICGSKDRNRALEGDFVAVELLDVDEVW 469
                 55777777788899****************************************************987733 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1339 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1375  (0.0766914); expected 358.6 (0.02)
Passed bias filter:                      590  (0.0329076); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.97u 0.35s 00:00:01.31 Elapsed: 00:00:00.52
# Mc/sec: 7774.27
//
Query:       EEA20445.1  [L=475]
Description: ubiquitin conjugating enzyme E2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.4e-33  115.5   0.0    2.4e-33  114.8   0.0    1.4  1  UQ_con     Ubiquitin-conjugating enzyme
  ------ inclusion threshold ------
      0.028   14.1   0.0      0.054   13.2   0.0    1.4  1  Prok-E2_B  Prokaryotic E2 family B
      0.059   13.7   0.0       0.13   12.5   0.0    1.6  1  RWD        RWD domain


Domain annotation for each model (and alignments):
>> UQ_con  Ubiquitin-conjugating enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.8   0.0     4e-37   2.4e-33      14     137 ..      21     150 ..       7     153 .. 0.88

  Alignments for each domain:
  == domain 1  score: 114.8 bits;  conditional E-value: 4e-37
                 TTTEEEEEEET...TEECEEEEEEEB.TTSTTTTEEEEEEEE--TTTTTS--EEEESST-SCTTBE.TTSBB-CGGGSTTT--TTSHHHHHHH...HHH CS
      UQ_con  14 psgisaklvdd...enlfewkvlikgpedtpYeggvFklelefpedYPlkpPkvkfvtkifHPnvd.ksGevcldiLkeekWspaltlesvll...siq 105
                 p+++  +++d+   ++l ++ v++ gp++tpY  g+++l+l++pedYP +pPk  f+t+i+HPnv+ ++G+vc+d Lk++ W++ ltl+++l+   +i 
  EEA20445.1  21 PPNYLFSPTDNqhsDDLSQLVVTLAGPHGTPYSAGMWRLQLRIPEDYPASPPKAAFKTRIWHPNVEeSTGAVCVDTLKRD-WESKLTLRDILVimqTIS 118
                 5555555566334589**************************************************9***********55.*********998656788 PP

                 HHHHS--TTS-SSHHHHHHHHHTHHHHHHHHH CS
      UQ_con 106 sLlaepnpesplnkeaakllkkdreeykkkvk 137
                  Ll +pnp+s+ln  a++ll++d +e+ ++++
  EEA20445.1 119 CLLIHPNPDSALNPMAGSLLQDDYNEFSRQAR 150
                 99**************************9986 PP

>> Prok-E2_B  Prokaryotic E2 family B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0     9e-06     0.054      34      98 ..      53     111 ..      27     121 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 9e-06
   Prok-E2_B  34 sggtvdlrlvypdsfpllppavflqdpeqlkllpHintfggaLClleeeldldewdpngsvadvl 98 
                 s+g  +l+l +p+++p +pp+ + + +    + p ++  +ga+C+    +  + w+++ +++d+l
  EEA20445.1  53 SAGMWRLQLRIPEDYPASPPKAAFKTRI---WHPNVEESTGAVCV---DTLKRDWESKLTLRDIL 111
                 78999*****************999999...**************...66666677777776665 PP

>> RWD  RWD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   2.2e-05      0.13      56     111 ..      58     119 ..      28     121 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 2.2e-05
                 EEEEEE-SSTTSS--EEEEEECC...SS-HHHHHHHHHHHHHHHHHT...TTS--CHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxx RF
         RWD  56 kleiklpeeYPeeaPiislsste...nlpkeqvksleekleelaeen...lgepvifalidw 111
                 +l+ + pe+YP ++P+ ++++     n++++  + + + l++ +e+      ++vi++ i+ 
  EEA20445.1  58 RLQLRIPEDYPASPPKAAFKTRIwhpNVEESTGAVCVDTLKRDWESKltlRDILVIMQTISC 119
                 6999***************9998788888999999999999999988777777888887775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (475 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       699  (0.0389871); expected 358.6 (0.02)
Passed bias filter:                      344  (0.0191868); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 3020.96
//
Query:       EEA20446.1  [L=168]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (168 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       824  (0.0459591); expected 358.6 (0.02)
Passed bias filter:                      282  (0.0157287); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.29s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 1171.41
//
Query:       EEA20447.1  [L=74]
Description: hypothetical protein PMAA_042860 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (74 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       465  (0.0259356); expected 358.6 (0.02)
Passed bias filter:                      285  (0.015896); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.43
# Mc/sec: 521.78
//
Query:       EEA20448.1  [L=150]
Description: hypothetical protein PMAA_042870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (150 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       451  (0.0251548); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.23s 00:00:00.63 Elapsed: 00:00:00.39
# Mc/sec: 1163.60
//
Query:       EEA20449.1  [L=150]
Description: hypothetical protein PMAA_042870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (150 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       451  (0.0251548); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.36u 0.26s 00:00:00.62 Elapsed: 00:00:00.39
# Mc/sec: 1165.61
//
Query:       EEA20450.1  [L=129]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-32  111.8   0.0      2e-32  111.5   0.0    1.1  1  MMgT      Membrane magnesium transporter


Domain annotation for each model (and alignments):
>> MMgT  Membrane magnesium transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.5   0.0   1.1e-36     2e-32       1     100 []       9     121 ..       9     121 .. 0.91

  Alignments for each domain:
  == domain 1  score: 111.5 bits;  conditional E-value: 1.1e-36
        MMgT   1 tlvglllLlHagYSahehsalls...........askkseqsatsLPlDitletlvslvllilglvlsaeeLkpIqlrkaagkierege..npfeeles 86 
                 t++gl+lL+HagYSaheh++l+s           + +++++ ++ +PlDit+e+l+++vl+++glvl++e+Lkp+  +++ag+iereg   np+++le 
  EEA20450.1   9 TFFGLVLLAHAGYSAHEHTTLYSnaalvasatstTPTSASNFFAVVPLDITIEALIAVVLVSTGLVLGSEKLKPVTHSAWAGQIEREGGakNPYKNLEI 107
                 589********************99999987664444445555699******************************************888******** PP

        MMgT  87 rpgfldirkkrkef 100
                 r+gf+d+rk r+ef
  EEA20450.1 108 RSGFWDVRKSRQEF 121
                 ************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (129 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       593  (0.0330749); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.23s 00:00:00.63 Elapsed: 00:00:00.40
# Mc/sec: 977.30
//
Query:       EEA20451.1  [L=230]
Description: eukaryotic translation elongation factor 1 subunit Eef1-beta, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.8e-33  114.5   3.5    1.8e-33  114.5   3.5    1.7  2  EF1_GNE         EF-1 guanine nucleotide exchange domain
    2.1e-09   37.6   6.3    2.1e-09   37.6   6.3    2.6  3  EF-1_beta_acid  Eukaryotic elongation factor 1 beta central a
    8.2e-05   22.7   0.4    0.00016   21.8   0.0    1.7  2  GST_C_3         Glutathione S-transferase, C-terminal domain
    0.00047   20.3   0.9     0.0014   18.8   0.0    2.2  2  GST_C           Glutathione S-transferase, C-terminal domain
  ------ inclusion threshold ------
      0.016   15.2   0.1       0.17   12.0   0.1    2.3  1  GST_C_2         Glutathione S-transferase, C-terminal domain
      0.033   14.3   0.1      0.051   13.7   0.1    1.3  1  Thioesterase    Thioesterase domain
        1.2    9.1   5.9       0.66    9.9   0.4    2.1  2  DNA_pol3_a_NII  DNA polymerase III polC-type N-terminus II


Domain annotation for each model (and alignments):
>> EF1_GNE  EF-1 guanine nucleotide exchange domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.2       3.1     8e+03       9      18 ..      98     107 ..      96     110 .. 0.83
   2 !  114.5   3.5   7.2e-37   1.8e-33       2      90 .]     147     230 .]     146     230 .] 0.98

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 3.1
                 SSS---HHHH CS
     EF1_GNE   9 eddetdleel 18 
                 +dd+ d+++l
  EEA20451.1  98 ADDDDDMDDL 107
                 6999999987 PP

  == domain 2  score: 114.5 bits;  conditional E-value: 7.2e-37
                 EEEEEEESSS---HHHHHHHHHH.HS-TSEE--.--EEE-SSS-EEEEEEEEESSS-GGGGHHHHHHTTS-S.....SEEEEEEEEEE- CS
     EF1_GNE   2 vvlevkPeddetdleelekkvksikleglvwgeasklepiafGlkkLqiscvieddkvstdeleekieeiegeledlVqsveivsfnkl 90 
                 v+levkP+ddetdl ++ek+v++i+++glvwg askl++++fG+kkLqi++v+ed+kvstdel+++ie    e ed+Vqs++i++++kl
  EEA20451.1 147 VTLEVKPWDDETDLVQMEKNVRAIEMDGLVWG-ASKLVAVGFGIKKLQINLVVEDEKVSTDELQQQIE----EDEDHVQSTDIAAMQKL 230
                 89******************************.7**********************************....78*************97 PP

>> EF-1_beta_acid  Eukaryotic elongation factor 1 beta central acidic region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -6.6   4.8         7   1.8e+04       4       8 ..      99     103 ..      98     106 .. 0.55
   2 !   37.6   6.3   8.2e-13   2.1e-09       1      28 []     107     135 ..     107     135 .. 0.90
   3 ?   -4.4   2.3         7   1.8e+04       6      10 ..     213     217 ..     213     218 .. 0.49

  Alignments for each domain:
  == domain 1  score: -6.6 bits;  conditional E-value: 7
  EF-1_beta_acid   4 SDDEE 8  
                     +DD++
      EEA20451.1  99 DDDDD 103
                     45555 PP

  == domain 2  score: 37.6 bits;  conditional E-value: 8.2e-13
  EF-1_beta_acid   1 LFGSDD.EEEDeEaerlreeRLaaYaaKK 28 
                     LFGSDD EEED+E+ + re RLa+Y++KK
      EEA20451.1 107 LFGSDDdEEEDPEVVKEREARLAEYKKKK 135
                     9**97527788*****************9 PP

  == domain 3  score: -4.4 bits;  conditional E-value: 7
  EF-1_beta_acid   6 DEEED 10 
                     +E+ED
      EEA20451.1 213 EEDED 217
                     34544 PP

>> GST_C_3  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   0.0   6.2e-08   0.00016      33      88 ..      12      62 ..       3      65 .. 0.88
   2 ?   -2.9   0.1       3.2   8.3e+03      91      97 ..     127     133 ..     110     144 .. 0.58

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 6.2e-08
                HHHHHHHHHCHGTSSSSTTS--HHHHHHHHHHHHHHHHTCCCC-HHHHHHHHHHHT CS
     GST_C_3 33 lkyfekvlkkkgggylvgdklTyADlalfqvldgleeaealkkfpklkalyervea 88
                l++ +++l+  +  y+vg++ + AD++ +++l+g   a   +k+p+++++y++++ 
  EEA20451.1 12 LAVANNFLS--TRSYIVGHSPSQADVVTYKALSGAPDA---AKYPHVARWYKHIAT 62
                566677787..788************************...79**********986 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 3.2
                 HHHHHHC CS
     GST_C_3  91 kikaYle 97 
                 ++++Y +
  EEA20451.1 127 RLAEYKK 133
                 2333322 PP

>> GST_C  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.0   5.3e-07    0.0014      35      90 ..      12      61 ..       8      64 .. 0.88
   2 ?   -2.3   0.2       2.1   5.5e+03      29      37 ..     122     130 ..     105     143 .. 0.50

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 5.3e-07
                HHHHHHHHHTSSSSSTTSSCHHHHHHHHHHHHHHHHTTTTTTTTSHHHHHHHHHHH CS
       GST_C 35 lsaleeelkkqdylvGdkltlADialvpilnwlqrlglafgqekfpnlkawlerim 90
                l+++++ l+++ y+vG  ++ AD++ + +l ++      ++ +k+p++ +w+++i+
  EEA20451.1 12 LAVANNFLSTRSYIVGHSPSQADVVTYKALSGA------PDAAKYPHVARWYKHIA 61
                7889999*******************9998765......44589**********97 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 2.1
                 HHHHHHHHH CS
       GST_C  29 ekvaevlsa 37 
                 ++  + l+ 
  EEA20451.1 122 KEREARLAE 130
                 222222222 PP

>> GST_C_2  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.1   6.5e-05      0.17      12      68 ..       9      58 ..       7      59 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 6.5e-05
                CHCHHHCTTT---SS.CTTCS--HHHHHHHHHHHHH.HHHHHS----TT-HHHHHHHH CS
     GST_C_2 12 daaldaleahLadspflfGdqptlaDialapflvrl.raagpgfdireaypnlraWle 68
                da l++ ++ L  ++++ G  p+ aD++ +  l  + +aa         yp++++W++
  EEA20451.1  9 DAGLAVANNFLSTRSYIVGHSPSQADVVTYKALSGApDAAK--------YPHVARWYK 58
                678999999999999************99999888866665........899999997 PP

>> Thioesterase  Thioesterase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.1     2e-05     0.051     116     193 ..      94     165 ..      76     186 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 2e-05
                   HTTHHTHHHHHCCTTHHHCCTTTHCCHHHHHHHHHHHHHHHHHTCCS-TTSCSEHHCEEEEEEGSS-CTCCCCCCCHC CS
  Thioesterase 116 raedeefveeltdlggtepeelledeellsellpalradyraleqyslrpeaaqklratlfngsddklkdldtlelae 193
                    a+  +  ++++dl g+ +++ +ed+e+++e + +l+++++ +e +++++ +     +tl++++ d ++dl+  ++++
    EEA20451.1  94 PAAAADDDDDMDDLFGS-DDDEEEDPEVVKEREARLAEYKKKKEAKPKPAAKSL---VTLEVKPWDDETDLV--QMEK 165
                   4444445689******9.***********************9999988888888...999999999999988..4444 PP

>> DNA_pol3_a_NII  DNA polymerase III polC-type N-terminus II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.9     0.087   2.2e+02      89     111 ..     113     139 ..     100     145 .. 0.57
   2 ?    9.9   0.4   0.00026      0.66      59     106 ..     183     229 ..     178     230 .] 0.66

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.087
  DNA_pol3_a_NII  89 keeeeekaike....aieakekkeaek 111
                      eee+ + +ke     +e k+kkea+ 
      EEA20451.1 113 DEEEDPEVVKErearLAEYKKKKEAKP 139
                     466666777774432222333333333 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.00026
  DNA_pol3_a_NII  59 ikfgFg..klkidvevdedesseeeieefeeqkeeeeekaikeaieakek 106
                      + gFg  kl+i+ +v++   ++ +++e+++q+ee e   ++  i+a++k
      EEA20451.1 183 VAVGFGikKLQINLVVED---EKVSTDELQQQIEEDEDHVQSTDIAAMQK 229
                     567788336666666666...56666788888888887777777777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (230 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       934  (0.0520944); expected 358.6 (0.02)
Passed bias filter:                      487  (0.0271627); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.48u 0.23s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 1633.28
//
Query:       EEA20452.1  [L=787]
Description: heat shock protein/chaperonin HSP78, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.6e-44  150.5   2.6    3.3e-43  147.7   0.0    3.0  2  AAA_2            AAA domain (Cdc48 subfamily)
    1.3e-35  121.5   2.2    1.3e-35  121.5   2.2    2.5  2  AAA_lid_9        AAA lid domain
    9.3e-27   92.9   0.1    3.3e-26   91.1   0.1    2.1  1  ClpB_D2-small    C-terminal, D2-small domain, of ClpB protein
    6.4e-19   68.7   0.8    2.6e-10   40.8   0.0    2.8  2  AAA              ATPase family associated with various cellul
    1.7e-11   44.3   0.0    4.3e-07   30.0   0.0    2.8  2  AAA_5            AAA domain (dynein-related subfamily)
    7.2e-10   39.5   2.8    0.00014   22.3   0.3    4.0  3  AAA_16           AAA ATPase domain
    1.5e-06   28.0   0.3     0.0012   18.5   0.0    2.4  2  Sigma54_activat  Sigma-54 interaction domain
    1.6e-06   28.5   4.2      0.024   14.9   0.0    4.1  3  AAA_22           AAA domain
    4.2e-06   26.8   0.0      0.017   15.2   0.0    2.8  2  AAA_14           AAA domain
    9.8e-06   25.1   0.1      0.016   14.6   0.0    3.6  2  TniB             Bacterial TniB protein
    1.4e-05   25.1   0.0      0.062   13.2   0.0    2.5  2  NACHT            NACHT domain
    4.6e-05   23.0   0.0       0.14   11.7   0.0    2.5  2  AAA_7            P-loop containing dynein motor region
    0.00011   22.0   0.0       0.23   11.2   0.0    2.6  2  IstB_IS21        IstB-like ATP binding protein
    0.00021   21.6   0.2      0.044   14.0   0.0    3.2  3  AAA_28           AAA domain
    0.00038   20.2   0.0       0.43   10.3   0.0    2.5  2  AAA_24           AAA domain
     0.0011   19.5   1.4       0.41   11.2   0.0    3.3  3  ABC_tran         ABC transporter
     0.0012   18.5   0.1       0.18   11.4   0.0    2.4  2  SRP54            SRP54-type protein, GTPase domain
     0.0013   19.3   1.1          3    8.4   0.0    3.1  2  AAA_18           AAA domain
     0.0022   18.0   0.0        5.8    6.9   0.0    3.4  3  ResIII           Type III restriction enzyme, res subunit
     0.0031   17.3   0.8      0.086   12.6   0.0    3.4  3  AAA_30           AAA domain
     0.0039   17.6   0.1          2    8.8   0.0    2.9  2  RNA_helicase     RNA helicase
     0.0057   16.1   0.4        2.1    7.7   0.1    3.0  2  Mg_chelatase     Magnesium chelatase, subunit ChlI
     0.0071   16.6   0.0        2.7    8.3   0.0    2.7  2  Roc              Ras of Complex, Roc, domain of DAPkinase
     0.0073   16.3   0.1        5.4    7.0   0.0    2.6  2  TsaE             Threonylcarbamoyl adenosine biosynthesis pro
     0.0078   16.0   0.0       0.41   10.4   0.0    2.6  2  PduV-EutP        Ethanolamine utilisation - propanediol utili
      0.008   16.1   9.2        2.6    7.9   0.0    4.4  5  ATPase_2         ATPase domain predominantly from Archaea
  ------ inclusion threshold ------
      0.013   15.4   1.4        3.3    7.6   0.0    2.7  2  RsgA_GTPase      RsgA GTPase
      0.026   14.9   3.1       0.17   12.2   0.4    3.1  2  AAA_19           AAA domain
      0.026   13.5   0.3       0.48    9.3   0.1    2.4  2  TrwB_AAD_bind    Type IV secretion-system coupling protein DN
      0.027   13.6   0.6        0.4    9.8   0.2    2.9  2  DUF815           Protein of unknown function (DUF815)
      0.033   14.4   0.0         11    6.2   0.0    2.7  2  AAA_33           AAA domain
      0.035   13.7   0.2       0.58    9.7   0.0    2.7  2  AAA_25           AAA domain
      0.066   12.5   0.0        6.7    5.9   0.0    2.5  2  Zeta_toxin       Zeta toxin
      0.067   13.0   2.4       0.97    9.2   0.0    3.1  3  AAA_21           AAA domain, putative AbiEii toxin, Type IV T
       0.16   11.8   0.3        6.2    6.6   0.0    2.6  2  AAA_29           P-loop containing region of AAA domain
       0.21   11.1   4.3       0.64    9.5   0.1    2.2  2  UvrD-helicase    UvrD/REP helicase N-terminal domain
       0.37   10.8   9.3       0.89    9.5   9.3    1.5  1  Rootletin        Ciliary rootlet component, centrosome cohesi
        1.1    8.5   4.7        1.9    7.8   4.7    1.4  1  FAM76            FAM76 protein
        7.9    6.9  10.9         20    5.6  10.9    1.7  1  CENP-H           Centromere protein H (CENP-H)


Domain annotation for each model (and alignments):
>> AAA_2  AAA domain (Cdc48 subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.0       0.6   2.8e+02       7      77 ..     122     199 ..     116     204 .. 0.73
   2 !  147.7   0.0   7.2e-46   3.3e-43       1     170 [.     514     686 ..     514     687 .. 0.96

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.6
                 EEE--TTSSHHHHHHHHHHHTT-..........-EEEEEGGG-------THHHHHHHHHTTT-HHHHTTS.EEEEETG CS
       AAA_2   7 lllgptgvGktelakalaellfv......kkekkliradaselleeeevehlvsrligappgyvgaeegG.ivllDEi 77 
                  l+g  g+Gkt + + la+ +         k+k++i +d  +l+ + + +   ++ + +    v+ +eg  i+++DE+
  EEA20452.1 122 VLIGAAGTGKTAILEGLAQRIVQgdvpesVKNKRVIALDLGSLIAGAKFRGDFEERLKSVLKEVEDAEGNvILFIDEL 199
                 678999999999888888877547778877888899999999988777776666666666666665555547788885 PP

  == domain 2  score: 147.7 bits;  conditional E-value: 7.2e-46
                 -----EEEE--TTSSHHHHHHHHHHHTT-....-EEEEEGGG-------THHHHHHHHHTTT-HHHHTTS............EEEEETGGG-------- CS
       AAA_2   1 rpiisilllgptgvGktelakalaellfvkkekkliradaselleeeevehlvsrligappgyvgaeegG............ivllDEidKihpkessg 87 
                 +p++s+++lgptgvGktel k++a +lf ++e+++ r+d+se++e    +h++srlig+p gyvg+++ G            ++l+DE +K+h+     
  EEA20452.1 514 KPLASFMFLGPTGVGKTELCKKMAGFLF-STESAVLRFDMSEFQE----KHTISRLIGSPAGYVGYDDAGqlteavrrkpyaVLLFDEFEKAHR----- 602
                 5899************************.9***************....*********************************************..... PP

                 -----HHHHHHHHHHHH--EE-------EE-TT-EEEEEE--TTHHHHTTTS-S.......TTTTSGGG--HHHHHHTT--HHHHTT--E CS
       AAA_2  88 advSregVqrdLLqileggtltdkqgrkvdtknilfImtgafgsskisdesrsk.......eeeeekkkeeveeelkkglipEllgRlpe 170
                       ++ ++LLq+l++g ltd+qg+kvd++n+++++t+++g++     +           +  e++k+ v++ +++   pE+l+R++e
  EEA20452.1 603 ------DISTLLLQVLDEGFLTDSQGHKVDFRNTIIVLTSNLGADILVGMDPLYkhklkdeGDVPEAIKKAVMDVVQASYPPEFLNRIDE 686
                 ......**************************************99988655547888888888999*********************97 PP

>> AAA_lid_9  AAA lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.5   2.2   2.7e-38   1.3e-35       1     102 [.     260     361 ..     260     366 .. 0.94
   2 ?    0.7   1.4       1.1   4.9e+02      65      92 ..     381     408 ..     360     421 .. 0.55

  Alignments for each domain:
  == domain 1  score: 121.5 bits;  conditional E-value: 2.7e-38
   AAA_lid_9   1 seeetieiLrglkekyekhHgvkisdealeaavklSkrYisdrflPdkAIDllDeaaarvrlkkeskpeeleklekelaklekekealekeeekekaer 99 
                 s++ ti+iLrg+k+kye hHgv+i+d+a++aa++ S+rYi+drflPdkAIDl+Deaa+++rl++eskpe++ +l++e+++++ e e+l+ke++ +++er
  EEA20452.1 260 SVASTISILRGIKNKYEVHHGVRITDAAIVAAATYSNRYITDRFLPDKAIDLVDEAASALRLQQESKPESILELDREITTIQIELESLRKETDVTSKER 358
                 5789****************************************************************************************9777776 PP

   AAA_lid_9 100 lke 102
                  ++
  EEA20452.1 359 RAK 361
                 655 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 1.1
   AAA_lid_9  65 eskpeeleklekelaklekekealekee 92 
                 ++++ee+e ++++ ++lek++ +lek++
  EEA20452.1 381 NKEKEEIEGIKRTKEDLEKSRFELEKAQ 408
                 3344455555555555555444444444 PP

>> ClpB_D2-small  C-terminal, D2-small domain, of ClpB protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.1   0.1   7.2e-29   3.3e-26       1      81 []     693     773 ..     693     773 .. 0.98

  Alignments for each domain:
  == domain 1  score: 91.1 bits;  conditional E-value: 7.2e-29
                    SCHHHHHHHHHHHHHHHHHHSCTTTEEEEEHHHHHHHHHHHTSBTTTBTCCHHHHHHHHTHHHHHHHHHTTSSSTTSEEEE CS
  ClpB_D2-small   1 LtkeelkkIvdlalkklekrlkergvelevtdealdalaekgydpeyGARpLrriiqreiedplaeeilsgelkegdtvrv 81 
                    L++++l++Ivd++lk+l+ rl +r+++l+v+de +++l+ekgydp+yGARpL+r+i +ei ++la++i++ge+++g t+rv
     EEA20452.1 693 LSRAALRDIVDIRLKELQGRLDDRRMTLQVDDETKQWLCEKGYDPRYGARPLNRLIAKEIGNRLADKIIRGEITPGHTARV 773
                    8999************************************************************************99986 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.8   0.0   5.6e-13   2.6e-10       2     126 ..     122     253 ..     121     258 .. 0.83
   2 !   25.5   0.0   3.1e-08   1.4e-05       2     111 ..     520     638 ..     519     645 .. 0.75

  Alignments for each domain:
  == domain 1  score: 40.8 bits;  conditional E-value: 5.6e-13
                 EEESSTTSSHHHHHHHHHHHH..........THEEEEEETTTCS..SSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHHTTCCCHHHHHHHHH CS
         AAA   2 llyGppGtGKTllakavakel..........gvefleisgsell..skyvgesekkirelfkeakekakpsilfiDEidalaksrsgseseeeervvnq 88 
                 +l+G  GtGKT++ + +a+ +          + +++ +++ +l+   k+ g+ e++++ ++ke++  ++ +ilfiDE++ l +     + e + ++ n 
  EEA20452.1 122 VLIGAAGTGKTAILEGLAQRIvqgdvpesvkNKRVIALDLGSLIagAKFRGDFEERLKSVLKEVEDAEGNVILFIDELHTLLGLG---KAEGSIDASNL 217
                 589*****************87776666665688*******9997778***************9888767************999...88999999999 PP

                 HHHHHHHTTTSSSTEEEEEEESSGGGSTHHHHS.TTSSE CS
         AAA  89 Llteldgvkkkeskvivigatnrpdkldpallr.gRfdr 126
                 L ++l++ + +   ++  ++ n+++ +++ + + +Rf+ 
  EEA20452.1 218 LKPALSRGELQ---CCGATTFNEYRLIEKDVALaRRFQA 253
                 99999999882...4444444557788777777778875 PP

  == domain 2  score: 25.5 bits;  conditional E-value: 3.1e-08
                 EEESSTTSSHHHHHHHHHHHH...THEEEEEETTTCSSS............STT.HHHHHHHHHHHHHHHTSTS.EEEEEETGGGHHHHHTTCCCHHHH CS
         AAA   2 llyGppGtGKTllakavakel...gvefleisgsellsk............yvg.esekkirelfkeakekakp.silfiDEidalaksrsgseseeee 83 
                 ++ Gp G+GKT l+k +a  l   ++ +l++++se+ +k            yvg + + ++ e +   ++k  p  +l++DE+++ +++    ++   +
  EEA20452.1 520 MFLGPTGVGKTELCKKMAGFLfstESAVLRFDMSEFQEKhtisrligspagYVGyDDAGQLTEAV---RRK--PyAVLLFDEFEKAHRDI---STLLLQ 610
                 789****************98655699**********999****999998877623344444444...444..559**********9888...555555 PP

                 HHHHHHHHHHHHTTTSSSTEEEEEEESS CS
         AAA  84 rvvnqLlteldgvkkkeskvivigatnr 111
                  + + +lt  +g k + +++i+++++n 
  EEA20452.1 611 VLDEGFLTDSQGHKVDFRNTIIVLTSNL 638
                 5556666666666666777888888876 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.0   0.00061      0.28       3      34 ..     122     155 ..     120     203 .. 0.58
   2 !   30.0   0.0   9.3e-10   4.3e-07       2     121 ..     519     637 ..     518     656 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00061
                 EEE--SSSSHHHHHHHGGGGB..S--EEEEE--T CS
       AAA_5   3 lLvGppGtgKselaerlaaal..nreveyvqltr 34 
                 +L+G+ GtgK+ + e la+++  ++  e v ++r
  EEA20452.1 122 VLIGAAGTGKTAILEGLAQRIvqGDVPESVKNKR 155
                 79*******************9555555554444 PP

  == domain 2  score: 30.0 bits;  conditional E-value: 9.3e-10
                 EEEE--SSSSHHHHHHHGGGGB...S--EEEEE--TT--HHHHH--B--..........--------..G-SEEEEESGGG--HHHHHHHHHHHHSSEE CS
       AAA_5   2 vlLvGppGtgKselaerlaaal...nreveyvqltrdtteedlkgrreik.ngttslvdsplvraar..egeilvlDEveraesevlnsLlslleerrl 94 
                 ++ +Gp+G+gK+el +++a +l   ++ v+   ++++ ++ ++   +    +       + l++a+r    ++l++DE+e+a++++   Ll++l+e  l
  EEA20452.1 519 FMFLGPTGVGKTELCKKMAGFLfstESAVLRFDMSEFQEKHTISRLIGSPaGYVGYDDAGQLTEAVRrkPYAVLLFDEFEKAHRDISTLLLQVLDEGFL 617
                 6899******************987444444455554444444444332225555566699******766689999********************977 PP

                 E..-SSSEEE---......-EEEEEES CS
       AAA_5  95 lleeggelvkaknddllerfrviatan 121
                   ++ g+ v+++n      + ++ t+n
  EEA20452.1 618 T-DSQGHKVDFRN------TIIVLTSN 637
                 7.88888888888......45555555 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.3   0.3     3e-07   0.00014       2      51 ..      99     145 ..      98     225 .. 0.77
   2 !   11.6   0.0   0.00058      0.27       3      63 ..     489     555 ..     487     569 .. 0.80
   3 ?   -0.5   0.0       3.1   1.4e+03     134     157 ..     586     610 ..     575     634 .. 0.75

  Alignments for each domain:
  == domain 1  score: 22.3 bits;  conditional E-value: 3e-07
      AAA_16   2 lvGReeeleqLlsalervrsgrpelvllsGesGvGKsslvrellralekd 51 
                 ++GR++e+++  ++l+r  ++   + +l+G++G+GK+++++ l++++ + 
  EEA20452.1  99 VIGRDAEIHRTIQVLSRRTKN---NPVLIGAAGTGKTAILEGLAQRIVQG 145
                 78******7776666655555...55899*************99988765 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 0.00058
      AAA_16   3 vGReeeleqLlsalervrsgrp......elvllsGesGvGKsslvrellralekdggiflrgkcdql 63 
                  G +e l+++++a+++ r+g +       + ++ G+ GvGK+ l ++ +  l  ++  +lr +  ++
  EEA20452.1 489 RGQDEALSAVANAVRMQRAGLSgenkplASFMFLGPTGVGKTELCKKMAGFLFSTESAVLRFDMSEF 555
                 6899999********888877777899999***************9988777666666666666666 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 3.1
      AAA_16 134 erp.lvlvlDdlqwadeaslqllaa 157
                 ++p  vl++D++++a  +  +ll +
  EEA20452.1 586 RKPyAVLLFDEFEKAHRDISTLLLQ 610
                 3445899******998877777443 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.1   0.0    0.0087         4       2     105 ..     100     202 ..      99     208 .. 0.70
   2 !   18.5   0.0   2.7e-06    0.0012      23     124 ..     517     619 ..     489     643 .. 0.79

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0087
                      ---SHHHHHHHHHHHHHCTSSS-EEEECSTTSSHHHHHHHHHHHSTTTTS-EEEEETTTS-TTCHHHHHHEBS.SSSSTTTSS-BEHHHHHTTT CS
  Sigma54_activat   2 igesealkelleqikkvaktdlsvlitGesGtGKellaraiheaskrkekpfvavncaaipeelleseLFGhe.kGaFtGAekekkGlfekadg 94 
                      ig++++++++++ +++ +k + +v + G  GtGK+ + + + ++  + + p    n   i+ +l  s + G + +G F    k+    +e a+g
       EEA20452.1 100 IGRDAEIHRTIQVLSRRTK-NNPV-LIGAAGTGKTAILEGLAQRIVQGDVPESVKNKRVIALDL-GSLIAGAKfRGDFEERLKSVLKEVEDAEG 190
                      6777777777777776543.3455.56********99998888777777776666666666554.44455543378888888888888888887 PP

                      S.EEEEETGGGS CS
  Sigma54_activat  95 G.tlfLDeigel 105
                        +lf+De+++l
       EEA20452.1 191 NvILFIDELHTL 202
                      635788888876 PP

  == domain 2  score: 18.5 bits;  conditional E-value: 2.7e-06
                      S-EEEECSTTSSHHHHHHHHHHHSTTTTS-EEEEETTTS-TTCHHHHHHEBSSSSSTTTSS-BE..HHHHHTTTSEEEEETGGGS-HHHHHHHH CS
  Sigma54_activat  23 lsvlitGesGtGKellaraiheaskrkekpfvavncaaipeelleseLFGhekGaFtGAekekk..GlfekadgGtlfLDeigelplelQekLl 114
                      +s + +G +G+GK+ l +++      +e+ ++++++++++e+   s+L G  +G + G +++ +   ++++    +l++De ++   ++ + Ll
       EEA20452.1 517 ASFMFLGPTGVGKTELCKKMAGFLFSTESAVLRFDMSEFQEKHTISRLIGSPAG-YVGYDDAGQltEAVRRKPYAVLLFDEFEKAHRDISTLLL 609
                      78899*****************99999***********************9998.56655443333566777789******************* PP

                      HHHHHSEEES CS
  Sigma54_activat 115 rvlqegever 124
                      +vl+eg ++ 
       EEA20452.1 610 QVLDEGFLTD 619
                      *****98764 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   5.2e-05     0.024       4      70 ..     117     184 ..     114     219 .. 0.76
   2 ?   -0.1   0.3       2.3   1.1e+03      94     105 ..     309     323 ..     232     387 .. 0.53
   3 !   11.4   0.1   0.00062      0.29      10     103 ..     521     600 ..     517     625 .. 0.66

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 5.2e-05
      AAA_22   4 tagilvvtGesGtGKTtllrrlleqldeeakaee.erpevvfvtlpsstsskdllrellralglelka 70 
                 t++  v++G +GtGKT  l+ l+++ ++   +e  ++++v+  +l s+   ++++ ++ + l++ lk+
  EEA20452.1 117 TKNNPVLIGAAGTGKTAILEGLAQRIVQGDVPESvKNKRVIALDLGSLIAGAKFRGDFEERLKSVLKE 184
                 778889*******************9877666668888888888887777777777777777766655 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 2.3
      AAA_22  94 lliiDEaqh.lr..s 105
                 + ++DEa   lr  +
  EEA20452.1 309 IDLVDEAASaLRlqQ 323
                 444555544443321 PP

  == domain 3  score: 11.4 bits;  conditional E-value: 0.00062
      AAA_22  10 vtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelkaerlsseellealeqalraravielliiDEaqhl 103
                   G++G+GKT l+++++  l         ++ v+++++++  +  ++ r +    g+++ +      +   +l++a+r++   ++l+ DE+++ 
  EEA20452.1 521 FLGPTGVGKTELCKKMAGFLFST------ESAVLRFDMSEFQEKHTISRLI----GSPAGY---VGYDDAGQLTEAVRRKPY-AVLLFDEFEKA 600
                 57**************9998543......5566677776666555554444....333334...444556666666666666.77777777765 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   3.7e-05     0.017       6      77 ..     122     203 ..     118     255 .. 0.79
   2 !    8.5   0.0    0.0043         2       8      89 ..     522     614 ..     518     630 .. 0.61

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 3.7e-05
      AAA_14   6 vitGaRrvGKTtllkqlikell.......vkkesilyinldderd.kkla.dpekllelileklke.ekktylflDEiqevp 77 
                 v+ Ga  +GKT +l+ l+++         vk+++++ ++l +    +k++ d+e+ l+ +l+++++ e++ +lf+DE + + 
  EEA20452.1 122 VLIGAAGTGKTAILEGLAQRIVqgdvpesVKNKRVIALDLGSLIAgAKFRgDFEERLKSVLKEVEDaEGNVILFIDELHTLL 203
                 7899**************98889**99999999999998888555333334566556666666444589999*****99874 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0043
      AAA_14   8 tGaRrvGKTtllkqlikellvkkesilyinldderdkkladpe............kllelileklkeekktylflDEiqev.pewekalkslvde 89 
                  G+  vGKT l+k+++  l+ +++ +l +++ + ++k   + +            +    + e ++++   +l++DE  ++ +++++ l +++de
  EEA20452.1 522 LGPTGVGKTELCKKMAGFLFSTESAVLRFDMSEFQEKH--TISrligspagyvgyDDAGQLTEAVRRKPYAVLLFDEFEKAhRDISTLLLQVLDE 614
                 6999************8888666666666666655532..2221233333444432222333332223344599999988734566666666665 PP

>> TniB  Bacterial TniB protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   3.5e-05     0.016      72     185 ..     142     257 ..     103     260 .. 0.75
   2 ?    3.2   0.0      0.11        51      36      55 ..     517     536 ..     500     543 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 3.5e-05
        TniB  72 vlvvqappkpdekrlyaaiLealgaplkararvskleqqvlrllrelkvr.vLiiDEihnlla.gsarkqreflnalksLgnelkipivlvGteealra 168
                 ++  ++p++ ++kr  a  L +l a +k r + ++  + vl+  ++ +   +L iDE+h ll  g+a+    + n+lk    + ++   ++ t + +r+
  EEA20452.1 142 IVQGDVPESVKNKRVIALDLGSLIAGAKFRGDFEERLKSVLKEVEDAEGNvILFIDELHTLLGlGKAEGSIDASNLLKPALSRGELQCCGATTFNEYRL 240
                 444556666666666666677777777777777766666666666655441789*******9549999999********99999*************** PP

        TniB 169 lrtDpqlasRFepialp 185
                 +++D  la+RF++i++ 
  EEA20452.1 241 IEKDVALARRFQAIQVS 257
                 ************99875 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.11
        TniB  36 pnlllvGdsnnGKtmivekF 55 
                  + +++G++ +GKt +++k 
  EEA20452.1 517 ASFMFLGPTGVGKTELCKKM 536
                 68899************986 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.2   0.0   0.00014     0.062       4      32 ..     122     150 ..     121     201 .. 0.84
   2 !    9.2   0.0    0.0023         1       5     112 ..     521     611 ..     518     622 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 0.00014
                 EEEC-TTTCHHHHHHHHHHHHCTS-SCCC CS
       NACHT   4 ilqGeaGsGKTtLlqklalawaegklpqg 32 
                 +l G+aG GKT+ l++la+ + +g+ p+ 
  EEA20452.1 122 VLIGAAGTGKTAILEGLAQRIVQGDVPES 150
                 689*********************99875 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.0023
                 EEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-...-HCHHHCCCCTS--SSS-CCHHHHCCSCCCEEEEEE-STT-SS-TCH.... CS
       NACHT   5 lqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgnarsladllfsqlpepaapvsevwavllelperlLlilDglDelvtdlgqkekq 103
                   G+ G+GKT L +k+a  + + +      + v+ + ++e++++    ++ +l+ s+    + +     ++ ++++  ++l++D ++++++d +     
  EEA20452.1 521 FLGPTGVGKTELCKKMAGFLFSTE------SAVLRFDMSEFQEKH---TISRLIGSPAGYVGYDDAGQLTEAVRRKPYAVLLFDEFEKAHRDIST---- 606
                 679************997776666......88999********96...67999999999999998888999*****************9998776.... PP

                 .....HHHH CS
       NACHT 104 pvrtlLsel 112
                     lL + 
  EEA20452.1 607 ----LLLQV 611
                 ....55555 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.6   0.0    0.0026       1.2      32      57 ..     117     142 ..     103     201 .. 0.82
   2 !   11.7   0.0    0.0003      0.14      35      83 ..     518     566 ..     512     569 .. 0.89

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0026
       AAA_7  32 nkkpvllvGptGtGKtviikdllkkl 57 
                  k++ +l+G +GtGKt+i++ l +++
  EEA20452.1 117 TKNNPVLIGAAGTGKTAILEGLAQRI 142
                 45667899**********99877765 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 0.0003
       AAA_7  35 pvllvGptGtGKtviikdllkkldkekylsltinfsaqtsanqlqdiie 83 
                 ++++ GptG+GKt ++k++   l +++  +l + +s   + +++ ++i 
  EEA20452.1 518 SFMFLGPTGVGKTELCKKMAGFLFSTESAVLRFDMSEFQEKHTISRLIG 566
                 689****************999999999999999999998888888775 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.0    0.0005      0.23      45     108 ..     116     183 ..     101     203 .. 0.79
   2 !    8.1   0.0    0.0045         2      49      88 ..     518     557 ..     513     616 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.0005
   IstB_IS21  45 ekkenivllGpsGvGKshlaialgveavragl..svlfvrv..edLveelkrarrdgklaralkrllk 108
                 ++k+n vl+G +G+GK+ +   l+++ v+ ++  sv   rv   dL + ++ a+  g ++++lk++lk
  EEA20452.1 116 RTKNNPVLIGAAGTGKTAILEGLAQRIVQGDVpeSVKNKRViaLDLGSLIAGAKFRGDFEERLKSVLK 183
                 578999********************999664336666655225788888888888888888887765 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0045
   IstB_IS21  49 nivllGpsGvGKshlaialgveavraglsvlfvrvedLve 88 
                 ++++lGp+GvGK+ l   ++     ++ +vl + ++++ e
  EEA20452.1 518 SFMFLGPTGVGKTELCKKMAGFLFSTESAVLRFDMSEFQE 557
                 6899***********9999988877777777666666555 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.0   0.0   9.6e-05     0.044       3      31 ..     122     151 ..     120     198 .. 0.72
   2 ?   -0.8   0.0       3.5   1.6e+03      75      95 ..     281     301 ..     238     374 .. 0.61
   3 ?    3.5   0.0      0.17        76       3      20 ..     520     537 ..     518     555 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 9.6e-05
      AAA_28   3 vitGgestGKTtlleaLaargyp.vvpEaa 31 
                 v++G+ +tGKT +le La+r ++  vpE++
  EEA20452.1 122 VLIGAAGTGKTAILEGLAQRIVQgDVPESV 151
                 89*****************95554667765 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 3.5
      AAA_28  75 vlfcDrglldtlaYaraygge 95 
                 v + D  +++ ++Y+ +y  +
  EEA20452.1 281 VRITDAAIVAAATYSNRYITD 301
                 556666666666666666553 PP

  == domain 3  score: 3.5 bits;  conditional E-value: 0.17
      AAA_28   3 vitGgestGKTtlleaLa 20 
                 +++G+ + GKT l++++a
  EEA20452.1 520 MFLGPTGVGKTELCKKMA 537
                 799***********9987 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.4   0.0    0.0073       3.4       3      59 ..     119     177 ..     117     209 .. 0.69
   2 !   10.3   0.0   0.00093      0.43       5      82 ..     519     605 ..     517     615 .. 0.70

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0073
      AAA_24   3 lkiliyGpsgiGKTtlakelgpkplfidtekGlksldadkfpdie..swedfldevvel 59 
                 ++ +++G +g+GKT ++  l ++++  d+ +++k+  ++ ++  +  + ++f+ +++e 
  EEA20452.1 119 NNPVLIGAAGTGKTAILEGLAQRIVQGDVPESVKNKRVIALDLGSliAGAKFRGDFEER 177
                 56689***************999999999999999888887644455444444444444 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00093
      AAA_24   5 iliyGpsgiGKTtlakelgpkplfidtekGlksldadkfpdieswedfldevvel...........aaeladyktlviDtideleelcl 82 
                 ++  Gp g+GKT l+k++    +++ te  + + d  +f++ +++  ++   +             a   ++y +l +D  +++ + ++
  EEA20452.1 519 FMFLGPTGVGKTELCKKM--AGFLFSTESAVLRFDMSEFQEKHTISRLIGSPAGYvgyddagqlteAVRRKPYAVLLFDEFEKAHRDIS 605
                 6779**************..556678999999999999887764444444333334555555666655667777777777777766655 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.0     0.095        44      15      35 ..     122     142 ..     113     198 .. 0.86
   2 ?   -0.0   0.7       2.5   1.2e+03      46      87 ..     334     389 ..     316     417 .. 0.59
   3 !   11.2   0.0   0.00088      0.41      14      52 ..     519     560 ..     508     626 .. 0.74

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.095
                 EEEESTTSSHHHHHHHHTTSS CS
                 xxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  15 aivGenGaGKStLlkllagll 35 
                 +++G  G+GK+ +l+ la+  
  EEA20452.1 122 VLIGAAGTGKTAILEGLAQRI 142
                 79************9998765 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 2.5
                 TCEGGG..B-HHHCCHCEEEE-SS..--S-TTSBHHHH..........HHHTCHHH CS
                 xxxxxx..xxxxxxxxxxxxxxxx..xxxxxxxxxxxx..........xxxxxxxx RF
    ABC_tran  46 gkdlke..qeleslrkeigvlpqe..pqlfpeltvren..........esdeeiek 87 
                 ++++++  +eleslrke  v ++e  ++l + l+ +++          +++eeie 
  EEA20452.1 334 DREITTiqIELESLRKETDVTSKErrAKLEEMLKTKQEevkklmdiwnKEKEEIEG 389
                 45555555778888888888888755555555543333566666666533444433 PP

  == domain 3  score: 11.2 bits;  conditional E-value: 0.00088
                 EEEEESTTSSHHHHHHHHTTSS--SEEEE.EETTCEGGG..B CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxx..x RF
    ABC_tran  14 vaivGenGaGKStLlkllagllkpteGei.lldgkdlke..q 52 
                   ++G++G GK+ L+k +ag l  te  + ++d+ +++e  +
  EEA20452.1 519 FMFLGPTGVGKTELCKKMAGFLFSTESAVlRFDMSEFQEkhT 560
                 5799****************9999888873456666666332 PP

>> SRP54  SRP54-type protein, GTPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0     0.044        20       5      27 ..     122     144 ..     118     161 .. 0.83
   2 !   11.4   0.0   0.00039      0.18       4      28 ..     519     543 ..     516     552 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.044
                 EEEESTTSSHHHHHHHHHHHHHH CS
       SRP54   5 llvGlqGaGKTttlaKLaallkk 27 
                 +l+G  G+GKT  l  La+++ +
  EEA20452.1 122 VLIGAAGTGKTAILEGLAQRIVQ 144
                 79****************98865 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00039
                 EEEEESTTSSHHHHHHHHHHHHHHT CS
       SRP54   4 illvGlqGaGKTttlaKLaallkke 28 
                 ++++G++G+GKT  + K+a  l + 
  EEA20452.1 519 FMFLGPTGVGKTELCKKMAGFLFST 543
                 79*****************887665 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.3   0.0     0.007       3.2       3      34 ..     123     160 ..     122     204 .. 0.63
   2 !    8.4   0.0    0.0064         3       3      18 ..     521     536 ..     520     634 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.007
      AAA_18   3 ltGtpGvGKttlakeLskrlgf.......gvnlrdvake 34 
                 l G++G+GKt + + L++r  +       + n r +a +
  EEA20452.1 123 LIGAAGTGKTAILEGLAQRI-VqgdvpesVKNKRVIALD 160
                 89**************9994.244555554444444444 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0064
      AAA_18   3 ltGtpGvGKttlakeL 18 
                   G+ GvGKt+l+k  
  EEA20452.1 521 FLGPTGVGKTELCKKM 536
                 57***********987 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.0     0.013       5.8      12      49 ..     106     143 ..     100     160 .. 0.83
   2 ?   -0.3   0.0         2   9.1e+02     124     144 ..     182     202 ..     161     218 .. 0.76
   3 ?    6.1   0.0     0.022        10       7      45 ..     490     537 ..     486     550 .. 0.76

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.013
                 HHHHT......TTSEEEEEESTTSTHHHHHHHHHHHH- CS
      ResIII  12 ienlleklkskrdkrglikmaTGtGKTlvaaklierll 49 
                 i ++++ l+ + +++ ++  a GtGKT ++  l++r+ 
  EEA20452.1 106 IHRTIQVLSRRTKNNPVLIGAAGTGKTAILEGLAQRIV 143
                 5677788876777788899**********988888765 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 2
                 ...HHHTTT-SEEEEETGGGT CS
      ResIII 124 eseellrdrfdviiiDEaHrl 144
                  +e  + + + +++iDE H l
  EEA20452.1 182 LKEVEDAEGNVILFIDELHTL 202
                 4555666677799******87 PP

  == domain 3  score: 6.1 bits;  conditional E-value: 0.022
                 HHHHHHHHHT...............TTSEEEEEESTTSTHHHHHHHHH CS
      ResIII   7 yQeeaienlleklks.........krdkrglikmaTGtGKTlvaakli 45 
                  Q ea+ ++++++           k    +++  +TG+GKT ++ k++
  EEA20452.1 490 GQDEALSAVANAVRMqraglsgenKPLASFMFLGPTGVGKTELCKKMA 537
                 6899999999888777777876534444999**********9877665 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.0   0.00019     0.086      21      44 ..     121     144 ..     107     199 .. 0.83
   2 ?   -0.6   0.0       2.1   9.5e+02     134     172 ..     463     501 ..     459     514 .. 0.69
   3 ?   -0.1   0.1       1.5   6.7e+02      23      39 ..     521     537 ..     511     548 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 0.00019
      AAA_30  21 avltGpAGtGKttalkalreawea 44 
                  vl G+AGtGKt +l++l++ + +
  EEA20452.1 121 PVLIGAAGTGKTAILEGLAQRIVQ 144
                 6899*************9776554 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 2.1
      AAA_30 134 GgvlrdlveaagigtaeLtevvRqkeseeraaalalreg 172
                 G ++++l++ +  + +++++  Rq+   + +a  a+++ 
  EEA20452.1 463 GIPVNKLMSGEVEKLIHMEDTLRQSVRGQDEALSAVANA 501
                 556677777777888888888998766666666665543 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 1.5
      AAA_30  23 ltGpAGtGKttalkalr 39 
                   Gp G GKt + k+++
  EEA20452.1 521 FLGPTGVGKTELCKKMA 537
                 579*******9998876 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   0.0      0.05        23       3      24 ..     123     144 ..     122     159 .. 0.83
   2 !    8.8   0.0    0.0044         2       2      20 ..     520     538 ..     519     602 .. 0.78

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.05
  RNA_helicase   3 lyGpsgeGKStlakeLakallk 24 
                   l G++g+GK+ + + La+++ +
    EEA20452.1 123 LIGAAGTGKTAILEGLAQRIVQ 144
                   78***************99974 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0044
  RNA_helicase   2 wlyGpsgeGKStlakeLak 20 
                   ++ Gp+g+GK+ l+k++a 
    EEA20452.1 520 MFLGPTGVGKTELCKKMAG 538
                   689*************764 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.0     0.031        14      22      58 ..     118     154 ..      96     172 .. 0.73
   2 !    7.7   0.1    0.0045       2.1      24      50 ..     518     544 ..     486     639 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.031
  Mg_chelatase  22 gHnlllvGppGsGKtmlakrlpsllpplseeealeva 58 
                   + n +l+G++G+GKt + + l++ + + +  e+++ +
    EEA20452.1 118 KNNPVLIGAAGTGKTAILEGLAQRIVQGDVPESVKNK 154
                   56779**********9988887766665555555555 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0045
  Mg_chelatase  24 nlllvGppGsGKtmlakrlpsllppls 50 
                   +++++Gp G GKt l k++++ l + +
    EEA20452.1 518 SFMFLGPTGVGKTELCKKMAGFLFSTE 544
                   5899****************9987654 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   0.0     0.046        21       3      24 ..     122     143 ..     121     161 .. 0.82
   2 !    8.3   0.0    0.0058       2.7       3      27 ..     520     544 ..     518     565 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.046
                 EEESSTTSSHHHHHHCHCT-CC CS
         Roc   3 vlvGdsgvGKtsllkrfvedkf 24 
                 vl+G +g+GKt +l+ + ++ +
  EEA20452.1 122 VLIGAAGTGKTAILEGLAQRIV 143
                 79***********998877655 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.0058
                 EEESSTTSSHHHHHHCHCT-CCC-E CS
         Roc   3 vlvGdsgvGKtsllkrfvedkfsek 27 
                 +++G +gvGKt l+k++    fs++
  EEA20452.1 520 MFLGPTGVGKTELCKKMAGFLFSTE 544
                 89*************9987666554 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.0     0.012       5.4       9      43 ..     108     142 ..     100     151 .. 0.76
   2 ?    6.4   0.0     0.018       8.3      21      42 ..     514     539 ..     490     547 .. 0.70

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.012
                 HHHHHHHHCHTEEEEEEESTTSSHHHHHHHHHHHT CS
        TsaE   9 algkklakalgdvilLeGdLGaGKTtlvrglakal 43 
                 +  + l + +++  +L G  G+GKT++  gla+ +
  EEA20452.1 108 RTIQVLSRRTKNNPVLIGAAGTGKTAILEGLAQRI 142
                 455555555566789*****************987 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.018
                 E....EEEEESTTSSHHHHHHHHHHH CS
        TsaE  21 v....ilLeGdLGaGKTtlvrglaka 42 
                      +++ G+ G+GKT l++++a  
  EEA20452.1 514 KplasFMFLGPTGVGKTELCKKMAGF 539
                 034448899************99865 PP

>> PduV-EutP  Ethanolamine utilisation - propanediol utilisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0      0.23   1.1e+02       5      23 ..     122     140 ..     118     157 .. 0.84
   2 !   10.4   0.0   0.00089      0.41       4      23 ..     519     538 ..     517     577 .. 0.74

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.23
   PduV-EutP   5 lliGkvgsGKttLtqalkg 23 
                 +liG+ g+GKt++ + l +
  EEA20452.1 122 VLIGAAGTGKTAILEGLAQ 140
                 79*********98877766 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00089
   PduV-EutP   4 illiGkvgsGKttLtqalkg 23 
                  +++G++g+GKt L++++ g
  EEA20452.1 519 FMFLGPTGVGKTELCKKMAG 538
                 69***************988 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   0.0     0.014       6.7       4      43 ..     102     141 ..     100     147 .. 0.88
   2 !    7.9   0.0    0.0056       2.6      99     138 ..     171     208 ..     145     219 .. 0.80
   3 ?   -2.2   2.0         7   3.2e+03      71     113 ..     355     397 ..     318     404 .. 0.53
   4 ?    3.5   0.0      0.13        58      26      43 ..     522     539 ..     511     568 .. 0.79
   5 ?   -1.5   0.0       4.2   1.9e+03     115     143 ..     586     610 ..     574     637 .. 0.65

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.014
    ATPase_2   4 RekelkeleeilerepneiyfiYGpegsGKtaLlkeiien 43 
                 R++e+ +  ++l+r +++  ++ G  g GKta+l  ++++
  EEA20452.1 102 RDAEIHRTIQVLSRRTKNNPVLIGAAGTGKTAILEGLAQR 141
                 999**999999999999999999**********9877765 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0056
    ATPase_2  99 sklvfkaielllekikkkgkkiiiiiDelqklidlglnga 138
                 + + ++ ++++l+++++    +i++iDel  l   gl +a
  EEA20452.1 171 RGDFEERLKSVLKEVEDAEGNVILFIDELHTLL--GLGKA 208
                 5677899************************99..66555 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 7
    ATPase_2  71 eeeekkklekalgiavpkaeleeilk..eksklvfkaiellleki 113
                  +e + kle++l  ++++ e++++++  +k k+  + i++ +e++
  EEA20452.1 355 SKERRAKLEEML--KTKQEEVKKLMDiwNKEKEEIEGIKRTKEDL 397
                 222223333333..4444445555555544444445555555555 PP

  == domain 4  score: 3.5 bits;  conditional E-value: 0.13
    ATPase_2  26 YGpegsGKtaLlkeiien 43 
                  Gp g+GKt L k+++  
  EEA20452.1 522 LGPTGVGKTELCKKMAGF 539
                 4************98755 PP

  == domain 5  score: -1.5 bits;  conditional E-value: 4.2
    ATPase_2 115 kkgkkiiiiiDelqklidlglngaellvk 143
                 + +   ++++De+ k+     + ++ll++
  EEA20452.1 586 R-KPYAVLLFDEFEKAH---RDISTLLLQ 610
                 2.233899*****9998...233345555 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.0     0.021       9.8      88     123 ..     108     142 ..      87     155 .. 0.74
   2 ?    7.6   0.0    0.0072       3.3     101     121 ..     518     538 ..     467     564 .. 0.79

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.021
                  TTHHHHHHHCTTSEEEEECSTTSSHHHHHHHHCTT- CS
  RsgA_GTPase  88 egleelkellkdktsvlvGqSGvGKStLinallpel 123
                  ++++ l+++  ++  vl+G  G GK+++++ l+++ 
   EEA20452.1 108 RTIQVLSRRT-KNNPVLIGAAGTGKTAILEGLAQRI 142
                  4444444444.45679*************9998875 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0072
                  EEEEECSTTSSHHHHHHHHCT CS
  RsgA_GTPase 101 tsvlvGqSGvGKStLinallp 121
                    +++G++GvGK+ L +++++
   EEA20452.1 518 SFMFLGPTGVGKTELCKKMAG 538
                  5789***********999876 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.4   0.00036      0.17      10      38 ..     118     146 ..     109     386 .. 0.88
   2 ?    1.6   0.1      0.71   3.3e+02      16      35 ..     522     541 ..     505     618 .. 0.53

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00036
      AAA_19  10 ekvllvtaGpGtGKTrvlkhivallvelg 38 
                 +++ ++++ +GtGKT +l++  + +v+  
  EEA20452.1 118 KNNPVLIGAAGTGKTAILEGLAQRIVQGD 146
                 5667899************9999988765 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.71
      AAA_19  16 taGpGtGKTrvlkhivallv 35 
                 +++ G GKT++ k++   l 
  EEA20452.1 522 LGPTGVGKTELCKKMAGFLF 541
                 45555555555444433333 PP

>> TrwB_AAD_bind  Type IV secretion-system coupling protein DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.1     0.001      0.48      11      52 ..     114     162 ..     105     175 .. 0.79
   2 ?    1.3   0.0      0.28   1.3e+02      17      35 ..     518     536 ..     510     553 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.001
  TrwB_AAD_bind  11 keretqhilivGttGsGKtqalekllrairarg.......draivlDlt 52 
                     +r ++  +++G++G+GKt  le+l + i +         +r+i lDl+
     EEA20452.1 114 SRRTKNNPVLIGAAGTGKTAILEGLAQRIVQGDvpesvknKRVIALDLG 162
                    5666777899***************999987767777776777777765 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.28
  TrwB_AAD_bind  17 hilivGttGsGKtqalekl 35 
                     ++++G tG GKt+  +k+
     EEA20452.1 518 SFMFLGPTGVGKTELCKKM 536
                    5899**********99987 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.2   0.00087       0.4      42     116 ..     107     199 ..      89     201 .. 0.67
   2 ?   -0.2   0.0      0.99   4.6e+02      28      76 ..     486     539 ..     467     567 .. 0.66

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00087
      DUF815  42 enteqfleglpannvLLwGarGtGKSslvkallneyaeeg.......Lrlievekedl...........kelpklvellrerperfilfvDDL 116
                 + t q l+ ++ nn +L+Ga GtGK +++  l +++ +          r+i ++  +l           + l+++++++++++ ++ilf+D L
  EEA20452.1 107 HRTIQVLSRRTKNNPVLIGAAGTGKTAILEGLAQRIVQGDvpesvknKRVIALDLGSLiagakfrgdfeERLKSVLKEVEDAEGNVILFIDEL 199
                 567888999999*******************99998876656666663333333222211111111112456667777777777777777765 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.99
      DUF815  28 ddLvgidkqkealventeqfleglpann.....vLLwGarGtGKSslvkallne 76 
                 ++++g d+  +a+ + ++   +gl+ +n      ++ G  G+GK  l+k +   
  EEA20452.1 486 QSVRGQDEALSAVANAVRMQRAGLSGENkplasFMFLGPTGVGKTELCKKMAGF 539
                 5566666666666666666555555544222227889*********99988755 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   0.0     0.024        11       4      22 ..     123     141 ..     122     194 .. 0.89
   2 ?    5.3   0.0     0.045        21       3      20 ..     520     537 ..     519     575 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.024
      AAA_33   4 lvGlpGsGKstlaerllkk 22 
                 l+G++G+GK+  +e+l+++
  EEA20452.1 123 LIGAAGTGKTAILEGLAQR 141
                 89*************9975 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.045
      AAA_33   3 llvGlpGsGKstlaerll 20 
                 ++ G+ G+GK+ l ++++
  EEA20452.1 520 MFLGPTGVGKTELCKKMA 537
                 899**********99987 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.0    0.0013      0.58      37     108 ..     122     196 ..     105     222 .. 0.73
   2 ?    0.5   0.1      0.86   3.9e+02      37      54 ..     520     537 ..     516     550 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0013
      AAA_25  37 llaGapgtGKttlaldlalavatGkpwlgpvapeqgkVl....yvsaEdsedelrrRlravgealrddarllvldl 108
                 +l+Ga gtGKt+++  la  +++G+ ++++v+++++  l    ++++   + ++++Rl+ v+++++d ++  +l +
  EEA20452.1 122 VLIGAAGTGKTAILEGLAQRIVQGD-VPESVKNKRVIALdlgsLIAGAKFRGDFEERLKSVLKEVEDAEGNVILFI 196
                 699********************99.77744333322222222445556666888888888888877766666665 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.86
      AAA_25  37 llaGapgtGKttlaldla 54 
                 ++ G++g+GKt l+  +a
  EEA20452.1 520 MFLGPTGVGKTELCKKMA 537
                 578********9998777 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0     0.067        31      12      40 ..     114     142 ..     103     152 .. 0.75
   2 ?    5.9   0.0     0.015       6.7      14      58 ..     513     559 ..     501     588 .. 0.77

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.067
  Zeta_toxin  12 sqerPklillgGqpGAGKselaellkdel 40 
                 s++++   +l G+ G GK++++e l++++
  EEA20452.1 114 SRRTKNNPVLIGAAGTGKTAILEGLAQRI 142
                 5555555667799**********999987 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.015
  Zeta_toxin  14 erPklill.gGqpGAGKselaellkdele.rqgnvvrldpDdlRelh 58 
                 ++P + ++  G +G GK+el ++++  l  +++ v+r+d  +++e h
  EEA20452.1 513 NKPLASFMfLGPTGVGKTELCKKMAGFLFsTESAVLRFDMSEFQEKH 559
                 6777777735999**************9967777889***9999999 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.0    0.0021      0.97       3      35 ..     122     149 ..     122     192 .. 0.77
   2 ?    1.2   0.6      0.56   2.6e+02      53     141 ..     324     410 ..     307     435 .. 0.80
   3 ?   -1.0   0.0       2.7   1.2e+03     255     267 ..     586     598 ..     579     600 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0021
      AAA_21   3 vliGpNgsGKSnLLdaldllarldrdvegltde 35 
                 vliG+ g+GK+ +L+ l      +r v+g+ +e
  EEA20452.1 122 VLIGAAGTGKTAILEGLA-----QRIVQGDVPE 149
                 8****************4.....4444444444 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.56
      AAA_21  53 dpeipfefeieeflsqgvryryglrlersqveeklssvetllesgllldkrsleeedvfnpeargirggvsvfslkelsvsepndlqfg 141
                 + ++++ +e++  +++ + ++ +   ++ +v +++ ++ +l+e   ++++++++ +d +n e+++i g+++ +++ e+s+ e ++ q++
  EEA20452.1 324 ESKPESILELD-REITTIQIELESLRKETDV-TSKERRAKLEEMLKTKQEEVKKLMDIWNKEKEEIEGIKRTKEDLEKSRFELEKAQRE 410
                 45666666666.7777777777777777777.788888888888888999999999999999999999999999999998888877765 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 2.7
      AAA_21 255 lkkgsllliDEpE 267
                 +k+ ++ll+DE+E
  EEA20452.1 586 RKPYAVLLFDEFE 598
                 44459*******9 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   0.0     0.014       6.2      19      42 ..     115     138 ..     106     145 .. 0.79
   2 ?    2.2   0.1      0.33   1.5e+02      24      37 ..     518     531 ..     508     543 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.014
      AAA_29  19 idlkgatlltGpsGsGKSTllDAi 42 
                  ++k++ +l+G+ G+GK+++l  +
  EEA20452.1 115 RRTKNNPVLIGAAGTGKTAILEGL 138
                 45566889************9765 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.33
      AAA_29  24 atlltGpsGsGKST 37 
                 ++++ Gp+G+GK+ 
  EEA20452.1 518 SFMFLGPTGVGKTE 531
                 4799********86 PP

>> UvrD-helicase  UvrD/REP helicase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.1    0.0014      0.64      12      39 ..     117     144 ..     108     159 .. 0.74
   2 ?    2.3   1.1      0.21        98     128     201 ..     320     392 ..     242     453 .. 0.63

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.0014
                    -SSEEEEEE-TTSSHHHHHHHHHHHHHH CS
  UvrD-helicase  12 lggpilveAsAGsGKTfvlaerilrlik 39 
                    ++++ +++ +AG+GKT++l+ +  r ++
     EEA20452.1 117 TKNNPVLIGAAGTGKTAILEGLAQRIVQ 144
                    5566677789********9877666555 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.21
                    HCCHHHHHHHHHSC.HSHTTTTHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCHHHHHHHHHHHTTCCTTHHCH CS
  UvrD-helicase 128 dlkqqellkellek.saddslnldkkkleklikelsksrnikkeelslskskaeelrelvskakekqlspkelkk 201
                     l+q++  + +le   +  + +++ + l+k++   sk+r    + +++ k k ee+++l++ + +++ + +  k+
     EEA20452.1 320 RLQQESKPESILELdREITTIQIELESLRKETDVTSKERR--AKLEEMLKTKQEEVKKLMDIWNKEKEEIEGIKR 392
                    3333333334443333344456666666666544444444..334444444444555544444444444433333 PP

>> Rootletin  Ciliary rootlet component, centrosome cohesion
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   9.3    0.0019      0.89      89     185 ..     315     407 ..     308     411 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.0019
   Rootletin  89 vnslLreqleearqaneaLtedlqkltkdwerlreeleqkekewreeeeafneylssehsrllsLWrevvavrrqfselksaterdLsklkseltrt 185
                   s Lr q e   ++  +L ++++ ++ ++e+lr+e +  +ke r + e++ +  ++e ++l+++W +    + +++ +k  t++dL+k + el ++
  EEA20452.1 315 AASALRLQQESKPESILELDREITTIQIELESLRKETDVTSKERRAKLEEMLKTKQEEVKKLMDIWNK---EKEEIEGIK-RTKEDLEKSRFELEKA 407
                 5689**************************************************************75...234444443.3555666666665555 PP

>> FAM76  FAM76 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   4.7    0.0041       1.9     224     289 ..     312     377 ..     269     408 .. 0.76

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0041
       FAM76 224 Lkeeiaslkkqleqkdqellekdkkitelkaellekekelreklkelekeakekieklekkirell 289
                 + e    l+ q e+k +++le d++it+++ el++ +ke+    ke++++ +e +++ ++++++l+
  EEA20452.1 312 VDEAASALRLQQESKPESILELDREITTIQIELESLRKETDVTSKERRAKLEEMLKTKQEEVKKLM 377
                 45566678889999*************999888877777665555555555555555555555553 PP

>> CENP-H  Centromere protein H (CENP-H)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6  10.9     0.045        20      13      79 ..     328     401 ..     320     409 .. 0.78

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.045
      CENP-H  13 sellklsqelrelqeeltevekenlrlkrknrelaaellelakekesek.......eklkeelekleaelkksr 79 
                 +++l+l +e++++q el++++ke+  ++++ r +++e+l++++e+ ++        +++ e +++ +++l+ksr
  EEA20452.1 328 ESILELDREITTIQIELESLRKETDVTSKERRAKLEEMLKTKQEEVKKLmdiwnkeKEEIEGIKRTKEDLEKSR 401
                 57999*********************************544444333336999665446666777778888877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (787 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1450  (0.0808746); expected 358.6 (0.02)
Passed bias filter:                      771  (0.043003); expected 358.6 (0.02)
Passed Vit filter:                       136  (0.00758548); expected 17.9 (0.001)
Passed Fwd filter:                        42  (0.00234257); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              39  [number of targets reported over threshold]
# CPU time: 0.94u 0.34s 00:00:01.28 Elapsed: 00:00:00.50
# Mc/sec: 4735.40
//
Query:       EEA20453.1  [L=930]
Description: DNA mismatch repair protein Msh5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-48  165.6   0.0    2.6e-48  164.5   0.0    1.5  1  MutS_V    MutS domain V
    1.3e-19   71.1   0.1      3e-19   70.0   0.1    1.6  1  MutS_III  MutS domain III


Domain annotation for each model (and alignments):
>> MutS_V  MutS domain V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  164.5   0.0     3e-52   2.6e-48       2     184 ..     674     866 ..     673     868 .. 0.90

  Alignments for each domain:
  == domain 1  score: 164.5 bits;  conditional E-value: 3e-52
                 EEE-STTSSHHHHHHHHHHHHHHHHHT--BSSSEEEEE--SEEEEEE--------SS-HHHHHHHHHHHHHTT--TTSEEEEESTS-SS-HHHHHHHHH CS
      MutS_V   2 litGpnmaGkstylrqvalivllaqiGsfvpaekaeisivdkiftRvgasDdlakgkstFmvEmlEtasilknatekslvilDElGRGtstydGlaial 100
                 l+tGpn +Gks+y++qvaliv la+iGs+vpa +aei+i+dki+tR+++ ++++k +stF ++++ ++ +lk +t++sl+i+DE G+Gt  +dG ++a 
  EEA20453.1 674 LLTGPNFSGKSVYMKQVALIVYLAHIGSYVPALNAEIGITDKILTRISTPETVSKIQSTFTLDLQQISLLLKFSTRRSLIIIDEFGKGTDLNDGAGLAC 772
                 89************************************************************************************************* PP

                 HHHHHHHH..TT--EEEEEES-GGGGGHHHH..STTEEEEEEEEE......EETTEEEEEEEEEES--SS--HHHHHHHTT--HHHHHHHHHHH CS
      MutS_V 101 avaeylle..kikaktlfatHyheltklaek..leevknlhlavk......eeeedivflykvkegaaeksyGikvaklaglPesvverArevl 184
                  ++eyll+    + k+l atH+he+ + +     +++   h++v+      + +e++++ly+ k+g +++s+G   a++ g+ e++v+rA+e +
  EEA20453.1 773 GIFEYLLSlgGERPKVLAATHFHEIFENRFLpeRPSLGFGHMEVRvdeeiaNAKEEVAYLYNFKPGRSNQSFGTLCAAMNGVGEAIVARASELV 866
                 ******962257999**********987644114555544555444476767889***********************************9875 PP

>> MutS_III  MutS domain III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.0   0.1   3.4e-23     3e-19       1     191 []     276     603 ..     276     603 .. 0.81

  Alignments for each domain:
  == domain 1  score: 70.0 bits;  conditional E-value: 3.4e-23
                 HHHHHTTSSS.....-TTS.............SSSS-HHHHH.---SSHHHHHHHHHHHH--BS-HHHHHHHHHHHHH.T....TT.HHHHHHHHTT-- CS
                 xxxxxxxxxx.....xxxxx............xxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xx..xxxxxxxxxxxxxxxx RF
    MutS_III   1 aTlrnLeile.....nlrgg............skegsLlgvl.drTvTamGaRlLrewllqPltdleeInaRldaVee.le..neelreelrellrrlp 78 
                 +Tl++L+i +     n   +            +++ sL+g+  ++  T++G+  Lr+ +l+P++dl++I++R+++ +  l   n+++ +++ + l++++
  EEA20453.1 276 NTLSSLQIMQteshpN---SfnqgprktssraKEDLSLYGLFhQHLLTPQGKSRLRQYFLRPSVDLDVISKRHKILDLlLLpaNKSTLQKMCSCLKKVK 371
                 7*******88555551...0333355444443444499999977888******************************84435566666777788***** PP

                 -HHHHHHHHHTT........---HHH.....HHHHHHHHHHHHTTTTT---SSTHHHHH........HHHH...HHHHHHB-SS--SSGGGS--B-T.. CS
                 xxxxxxxxxxxx........xxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxx...xxxxxxxxxxxxxxxxxxxxxxx.. RF
    MutS_III  79 DleRllsrislg........kakard.....lkallealkaleelvallekeklaesee........esla...elleeaideeplalekegedlra.. 151
                 ++  +++ +++g        k          l++++++  +l+e v+ ++ +++ + +e         sl+   +l+ ++id e++++++++ +++   
  EEA20453.1 372 NMCPVMTTLHKGlssafggfK----GtiwgsLLNFATHTLDLQEAVREMGCQDMVSFRErmletldvGSLHavgRLIYQTIDIEDSQEQQRTVIKQGvd 466
                 *******99997443333331....03333333434433345666666666655555555555555533334558999********************* PP

                 .................................................................................................HH CS
                 .................................................................................................xx RF
    MutS_III 152 .................................................................................................ie 153
                                                                                                                    
  EEA20453.1 467 rdldllktryngldgllkqvaidvastipanlqievnviyfpqlgfniaipfdttgraaytgsggtweqvfttenrayfkdermreldeklgdiyslVC 565
                 ***********************************************************************************************9977 PP

                 HHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    MutS_III 154 aleqelfqelleeveealerlrrlaealaeLDvllSlA 191
                 ++e e+ +e+ ++v ++ ++l +++e++ eLD+ l++A
  EEA20453.1 566 EREIEIAHEIAQNVLKYEKVLSACSELCGELDCYLAMA 603
                 7777799****************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (930 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       486  (0.0271069); expected 358.6 (0.02)
Passed bias filter:                      440  (0.0245412); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.70u 0.35s 00:00:01.04 Elapsed: 00:00:00.52
# Mc/sec: 5410.52
//
Query:       EEA20454.1  [L=650]
Description: Sas10/Utp3 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.4e-28   99.1  10.6    1.4e-28   99.1  10.6    4.5  4  Sas10       Sas10 C-terminal domain
    8.6e-12   45.5   0.0    8.6e-12   45.5   0.0    3.5  3  Sas10_Utp3  Sas10/Utp3/C1D family


Domain annotation for each model (and alignments):
>> Sas10  Sas10 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.1   5.3         2   1.8e+04      28      53 ..     353     378 ..     347     393 .. 0.68
   2 ?   -1.5   0.8       0.4   3.6e+03      25      51 ..     442     468 ..     436     492 .. 0.78
   3 ?    2.2   1.8     0.029   2.6e+02      30      58 ..     540     568 ..     538     573 .. 0.90
   4 !   99.1  10.6   1.6e-32   1.4e-28       2      74 .]     576     650 .]     575     650 .] 0.98

  Alignments for each domain:
  == domain 1  score: -4.1 bits;  conditional E-value: 2
       Sas10  28 pRvkkrkkYekakkklksqvaevkke 53 
                 ++ kk  k ++++kkl++ ++ ++k 
  EEA20454.1 353 SKEKKSTKSAQKEKKLSKSQQAAEKA 378
                 56677777777777777766666533 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.4
       Sas10  25 nrnpRvkkrkkYekakkklksqvaevk 51 
                 +  +R+k   ++   ++  k +++++ 
  EEA20454.1 442 EEKARKKRSLRFYTSQIAQKANKRNAA 468
                 567888888999888888888887766 PP

  == domain 3  score: 2.2 bits;  conditional E-value: 0.029
       Sas10  30 vkkrkkYekakkklksqvaevkkeegkYs 58 
                 v  r+k +ka kk +   ae+ ++ ++Y+
  EEA20454.1 540 VAARNKQKKADKKARAEEAEAAQKGERYE 568
                 6789******************9999997 PP

  == domain 4  score: 99.1 bits;  conditional E-value: 1.6e-32
       Sas10   2 dgkRkityqIekNkGLtpkRkkenrnpRvkkrkkYekakkklksqvaevk..keegkYsGektGIksnvvkSvkL 74 
                 dgkR+ityqIekNkGLt+kR+k++rnpRvkkrkk+e++kkkl+s ++++k  + +g+Y+Ge tGIk+n+vkSvkL
  EEA20454.1 576 DGKRRITYQIEKNKGLTAKRNKDVRNPRVKKRKKFEQKKKKLASIRQVYKggEGRGGYAGELTGIKKNLVKSVKL 650
                 89************************************************988889******************8 PP

>> Sas10_Utp3  Sas10/Utp3/C1D family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.5      0.66   5.9e+03       4      33 ..      60      98 ..      58     107 .. 0.60
   2 !   45.5   0.0   9.6e-16   8.6e-12       1      86 [.     221     316 ..     221     316 .. 0.85
   3 ?   -6.1   6.0         2   1.8e+04      17      17 ..     377     377 ..     340     436 .. 0.61

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.66
  Sas10_Utp3  4 lsksldelqeslepllskakaee..kkslsd.......e 33
                l+++  +lq+s e++l ++++e+  +++++d       +
  EEA20454.1 60 LQEEEADLQPSDEEVLGYDEDEDelDDDDDDeyendytS 98
                666667888888888888777775532333334444444 PP

  == domain 2  score: 45.5 bits;  conditional E-value: 9.6e-16
  Sas10_Utp3   1 leslsksldelqeslepllskakaee...kkslsdeklsegisllslKnelllaYllnlllylllk.lsg..............velkdhpvvkeLvrl 81 
                 +e+l+k++ +lq+    +l++a+++e   +        +  +++  +K+++l++Yl ++++y  ++ l++              +el+dhp++ +Lv++
  EEA20454.1 221 FEPLAKDFVDLQTEYTTILADAQKAEeamD------GSETSVPVPIIKFRALASYLGSISMY--FAlLTSpaedgdgktvalspTELRDHPIMGSLVKC 311
                 689*****************8666664431......2334578*******************..55455569*************************** PP

  Sas10_Utp3  82 Rvyle 86 
                 R+ +e
  EEA20454.1 312 RQQWE 316
                 ***98 PP

  == domain 3  score: -6.1 bits;  conditional E-value: 2
  Sas10_Utp3  17 p 17 
                 +
  EEA20454.1 377 K 377
                 0 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (650 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2603  (0.145184); expected 358.6 (0.02)
Passed bias filter:                      587  (0.0327403); expected 358.6 (0.02)
Passed Vit filter:                       117  (0.00652574); expected 17.9 (0.001)
Passed Fwd filter:                        36  (0.00200792); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 1.33u 0.39s 00:00:01.72 Elapsed: 00:00:00.54
# Mc/sec: 3609.37
//
Query:       EEA20455.1  [L=356]
Description: 3-ketosphinganine reductase (Tsc10), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.2e-20   72.9   0.0    3.5e-20   72.3   0.0    1.3  1  adh_short        short chain dehydrogenase
    1.7e-13   50.7   0.0    2.5e-13   50.1   0.0    1.2  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    1.6e-09   38.0   0.1    2.5e-09   37.3   0.1    1.5  1  KR               KR domain
    4.4e-06   26.3   0.0      6e-06   25.9   0.0    1.2  1  Epimerase        NAD dependent epimerase/dehydratase family
     0.0002   20.7   0.0    0.00032   20.0   0.0    1.3  1  THF_DHG_CYH_C    Tetrahydrofolate dehydrogenase/cyclohydrolas
    0.00021   20.8   0.0    0.00031   20.3   0.0    1.2  1  GDP_Man_Dehyd    GDP-mannose 4,6 dehydratase
     0.0016   18.7   0.0     0.0024   18.1   0.0    1.3  1  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma
     0.0092   15.1   0.0      0.016   14.4   0.0    1.3  1  RmlD_sub_bind    RmlD substrate binding domain
  ------ inclusion threshold ------
      0.017   15.0   0.0      0.025   14.4   0.0    1.3  1  3HCDH_N          3-hydroxyacyl-CoA dehydrogenase, NAD binding
      0.042   14.1   0.1      0.072   13.3   0.1    1.3  1  Herpes_heli_pri  Herpesvirus helicase-primase complex compone
      0.093   12.6   0.0       0.22   11.4   0.0    1.7  2  NAD_binding_10   NAD(P)H-binding
       0.12   12.3   0.0         11    6.0   0.0    2.3  2  NAD_Gly3P_dh_N   NAD-dependent glycerol-3-phosphate dehydroge


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.3   0.0   2.4e-23   3.5e-20       1     170 [.      38     224 ..      38     228 .. 0.90

  Alignments for each domain:
  == domain 1  score: 72.3 bits;  conditional E-value: 2.4e-23
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT.....TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSE..SEEEE---SS--SS CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee.....gakalaiqvDvtdreevealvekavkklgkl..dvLvnNAGitgsgp 92 
                 k++l+tGas+G+Gr ia +la++Ga+vv+++rs+ kle++++ +k++      +++++i++D+td +++++l+e+      ++  dv+  +AG  ++g 
  EEA20455.1  38 KTILITGASEGLGRSIAIQLAQKGANVVIASRSAHKLETAIADIKAAavnpsTQRFHFISADLTDPDAADRLLEETTTWNNGVapDVVWCCAGYCHPGL 136
                 79*******************************************9988887788*********************888877777************** PP

                 GGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHH...HCTTEE.......EEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGG CS
   adh_short  93 fselseeewervievNltgvflltravlpaml...kqssGr.......IvnvsSvagkvpvagvaaYsAsKaavagltrslakelapt 170
                 f ++  ++ ++ +++ +     +++a l+ +l   +q  G+        ++++S+ +   v g+++Ys  Kaa++ l++ l +e++ +
  EEA20455.1 137 FIDVPIKTLRDQMDTVYWTSAYTAHATLRRWLvpvSQTTGKehppprhLIFTASTLAVFTVSGYSPYSPPKAAMRNLSDVLVQEIEMY 224
                 ********9999998888888888888888777997777744444444*********************************9998765 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.1   0.0   1.7e-16   2.5e-13       1     155 [.      44     217 ..      44     225 .. 0.79

  Alignments for each domain:
  == domain 1  score: 50.1 bits;  conditional E-value: 1.7e-16
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGH.HHHHHHHHHHTT...SE.E..EE--TTSHHHHHHHHHHHHHHHSSE..EEEEE-----EGCSS-GG CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneea.kkrveelaeelg...ae.v..lecDVtdeeqvealveevvekfgkl..Dilvnnagiapklkgpfl 88 
                   Ga +g+Gr iA +la++Ga+vv++ ++  + + ++++++++     ++ +  + +D td+++ ++l ee++   +++  D++  +ag++++  g f+
    EEA20455.1  44 GASEGLGRSIAIQLAQKGANVVIASRSAHKlETAIADIKAAAVnpsTQrFhfISADLTDPDAADRLLEETTTWNNGVapDVVWCCAGYCHP--GLFI 138
                   899***************************9999999988764343224367******************998855444************..5555 PP

                   G....H-HHHHHHHHHHHTHHHHHHHHHHHH.HCTSC.......CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHH CS
  adh_short_C2  89 e....tsreefdraldvnlyslfllakaalp.lmkeg.......gsivnlssvgaervvpnynaygaaKaalealtryl 155
                   +    t r+++d++  +++y +++++++ l  + + +         ++ ++s+ a  +v++y+ y+  Kaa+ +l+  l
    EEA20455.1 139 DvpikTLRDQMDTVYWTSAYTAHATLRRWLVpVSQTTgkehpppRHLIFTASTLAVFTVSGYSPYSPPKAAMRNLSDVL 217
                   5111156677777777788888777777655444433455688888**************************9987655 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.3   0.1   1.7e-12   2.5e-09       2      82 ..      39     120 ..      38     210 .. 0.86

  Alignments for each domain:
  == domain 1  score: 37.3 bits;  conditional E-value: 1.7e-12
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHT..T-EEEE----TT-HHHHHHHHHHHHHHSS-- CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaeleal..gaevevvaaDvsdkdavealleeikaeeppi 82 
                 t litG+  gLG+++a +la+kga ++v+ sRsa++ e++ a i++ + +    + ++++aD++d+da  +llee ++ ++ +
  EEA20455.1  39 TILITGASEGLGRSIAIQLAQKGA-NVVIASRSAHKLETAIADIKAAAVNpsTQRFHFISADLTDPDAADRLLEETTTWNNGV 120
                 679********************8.68999***9988888887776655433679*******************998766544 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.9   0.0     4e-09     6e-06       1     124 [.      40     180 ..      40     222 .. 0.77

  Alignments for each domain:
  == domain 1  score: 25.9 bits;  conditional E-value: 4e-09
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC...........EEEE--TT-HHHHHHHHHH.......HT-SEEEE--S---HHHHH CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl...........elveldltdrsalerlfke.......eqpdavihlAavggvaass 81 
                 il+tGa+  +G+ ++ +l++kg +v+  +r  ++ +ta  + +           +++ +dltd++a +rl++e       ++pd+v  +A++++++  +
  EEA20455.1  40 ILITGASEGLGRSIAIQLAQKGANVVIASRSAHKLETAIADIKaaavnpstqrfHFISADLTDPDAADRLLEEtttwnngVAPDVVWCCAGYCHPGLFI 138
                 8*************************9999977777665555599*************************9985555544579**************99 PP

                 HSHHHHHHHHTHHHHHHHHHHHHHTCTEEEEEEEGGGGTSCSS CS
   Epimerase  82 edpadfieknlqgtlnlleaarkagvkrllflsSsevYGkdae 124
                 + p +++++ +  ++    +   a ++r l   S ++ Gk ++
  EEA20455.1 139 DVPIKTLRDQMDTVYWTSAYTAHATLRRWLVPVS-QTTGKEHP 180
                 9999999988777766666666666666666666.55566665 PP

>> THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   0.0   2.2e-07   0.00032      31      87 ..      32      86 ..      18     106 .. 0.78

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 2.2e-07
                   T---TT-EEEEE---TTTHHHHHHHHHCTT-EEEEE-TTSCCHHHHHCCSSEEEE-S CS
  THF_DHG_CYH_C 31 gielegkkvvvvGrsnivgkplallLleknatVtvchsktkdlaeitreadivvvav 87
                   +  ++gk++++ G+s+ +g+++a+ L++k+a V ++ +++++l++ +  adi  +av
     EEA20455.1 32 QFPVNGKTILITGASEGLGRSIAIQLAQKGANVVIASRSAHKLETAI--ADIKAAAV 86
                   6789***********************************99998765..56655554 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0     2e-07   0.00031       1      74 [.      41     113 ..      41     146 .. 0.83

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 2e-07
                    EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TT..HHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHHHH CS
  GDP_Man_Dehyd   1 LiTGiaGfiGsylaelLlekgyevhgivrrsssfnt..griehlakdpkeeleenlklhkgDltDssslerllaev 74 
                    LiTG +   G  +a +L +kg +v++  r + +++t  + i++ a +p    +++++++++DltD ++ +rll+e+
     EEA20455.1  41 LITGASEGLGRSIAIQLAQKGANVVIASRSAHKLETaiADIKAAAVNP---STQRFHFISADLTDPDAADRLLEET 113
                    899999999***************999988777665114455555444...468*******************997 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   1.6e-06    0.0024       1      70 [.      40     113 ..      40     167 .. 0.83

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 1.6e-06
                      EEEE--.SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHH.......TTTCEEEEE--TTTHHHHHHHHHTTS CS
  Sacchrp_dh_NADP   1 vliiGa.GsvGqavaellarhfdvdaeitvadrskeklealaaka.......lgvrfeaialdaenyeavLaallkeg 70 
                      +li Ga  + G+++a  la+++    ++++a+rs +kle ++a++       + +rf++i+ d  +++a  ++ll+e+
       EEA20455.1  40 ILITGAsEGLGRSIAIQLAQKGA---NVVIASRSAHKLETAIADIkaaavnpSTQRFHFISADLTDPDA-ADRLLEET 113
                      6778888889**********997...6****************99************************.*****998 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.0     1e-05     0.016       2      61 ..      39     131 ..      38     134 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1e-05
                    EEEEESTTSHHHHHHHHHCTTTSEEEEEE-TT..........................T--TTSHHHHHHHH.......HHH--SEEEE---- CS
  RmlD_sub_bind   2 kilvtGanGqlGseLakqlaeeglevlaltre..........................eldltdaeavaell.......keakpdvvvnaAAy 61 
                    +il+tGa+  lG+ +a qla++g++v+  +r+                          ++dltd++a+++ll       + + pdvv  +A y
     EEA20455.1  39 TILITGASEGLGRSIAIQLAQKGANVVIASRSahkletaiadikaaavnpstqrfhfiSADLTDPDAADRLLeetttwnNGVAPDVVWCCAGY 131
                    69************************99999999**999999999999999999999999999999999999555555555678888888877 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   1.7e-05     0.025      10      46 ..      49      85 ..      39     119 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.7e-05
                CHHHHHHHHHHTT-EEEEE-S-HHHHHHHHHHHHHHH CS
     3HCDH_N 10 mGagiaavfasagleVvlvdiseealekalekieksl 46
                +G++ia ++a++g +Vv+  +s+++le+a + i++  
  EEA20455.1 49 LGRSIAIQLAQKGANVVIASRSAHKLETAIADIKAAA 85
                7*******************************99844 PP

>> Herpes_heli_pri  Herpesvirus helicase-primase complex component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.1   4.8e-05     0.072      39      78 ..     164     203 ..     136     211 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 4.8e-05
  Herpes_heli_pri  39 aafWlvPlsfleskpvaPklpvdclapklfiltkdGPlcy 78 
                       + WlvP s +++k   P+      a++l ++t +G  +y
       EEA20455.1 164 LRRWLVPVSQTTGKEHPPPRHLIFTASTLAVFTVSGYSPY 203
                      467*********************************8887 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00015      0.22       1      60 [.      44     112 ..      44     169 .. 0.79
   2 ?   -2.7   0.0       3.2   4.7e+03     111     149 ..     215     253 ..     195     272 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00015
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCH..........HHHCTTTCEEEE--TT-CCHHHHHHTT CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpekla..........eleaeeglevvegdvtdvedlaealkg 60 
                     GA+ + Gr ++ +l+++g  +v++  R+++kl+            +++++ + +++d+td+++  + l+ 
      EEA20455.1  44 GASEGLGRSIAIQLAQKG-ANVVIASRSAHKLEtaiadikaaaVNPSTQRFHFISADLTDPDAADRLLEE 112
                     89999************5.9********999986666555442223567888899999999998888883 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 3.2
                     HHHHHCCHHHHHHHHHHHHHHHHSSSEEEEEEE-CEE-S CS
  NAD_binding_10 111 ewnkellkaylaakraaeellrasgldwTivrpggLtde 149
                     ++  + ++ y  a r+ ++   a++++  iv p g+t  
      EEA20455.1 215 DVLVQEIEMYNGARRKKDADAPATDVKIHIVFPMGMTSP 253
                     444455666667777777777788888888888777765 PP

>> NAD_Gly3P_dh_N  NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0     0.034        50      11      40 ..      50      83 ..      40     106 .. 0.79
   2 ?    6.0   0.0    0.0071        11      90     126 ..     273     309 ..     262     312 .. 0.77

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.034
                    HHHHHHHHHTTT--EEEE-S-H....HHHHHHHH CS
  NAD_Gly3P_dh_N 11 GtalAkvlaenghevrlwvree....elieeine 40
                    G ++A+ la++g +v++ +r++      i +i++
      EEA20455.1 50 GRSIAIQLAQKGANVVIASRSAhkleTAIADIKA 83
                    99***************99999544444445555 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.0071
                     CCC--TT-EEEE---SEET.TTEEHHHHHHHHH-S-- CS
  NAD_Gly3P_dh_N  90 kgllkkkailvsliKGieegtlkllsevieeelkeek 126
                     ++   ++ ++ ++iKG+e+g  ++++++i +++ +++
      EEA20455.1 273 DKPQLPEEVASIAIKGLERGDFQIITNAIGQIMRSSA 309
                     4444566677789******************998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (356 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       532  (0.0296726); expected 358.6 (0.02)
Passed bias filter:                      477  (0.0266049); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.50u 0.29s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 2421.92
//
Query:       EEA20456.1  [L=2252]
Description: myosin class II heavy chain (MHC), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.2e-05   21.8  70.7      0.029   13.2  14.3    4.4  4  Spc7      Spc7 kinetochore protein
  ------ inclusion threshold ------
      0.022   14.4   8.8      0.085   12.6   0.0    3.9  4  PAM2      Ataxin-2 C-terminal region
       0.39   10.2  77.8        7.4    6.1  10.1    4.7  3  Filament  Intermediate filament protein
        9.6    5.5  15.9        0.5    9.7   0.6    4.0  4  FliD_C    Flagellar hook-associated protein 2 C-terminus


Domain annotation for each model (and alignments):
>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.2  14.3   6.5e-06     0.029     150     290 ..    1475    1618 ..    1469    1641 .. 0.86
   2 !    8.6  17.4   0.00017      0.76     143     276 ..    1674    1803 ..    1666    1804 .. 0.78
   3 !   12.6  15.9     1e-05     0.047     155     286 ..    1803    1936 ..    1800    1949 .. 0.84
   4 !    4.6   0.8    0.0028        13     218     255 ..    1982    2019 ..    1965    2068 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 6.5e-06
        Spc7  150 gleedkelLekqeee..ldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqks 244 
                  +  ++ + L++q+++  +++l++e  + +a+ +++ + l ea+e  +++ k +L  +++ l+++++  e+  k   ++qe l+e+++ + +++ + +
  EEA20456.1 1475 ETLAELKALTQQRQQpdIKTLVQEALAVHAQANARKTPLSEAEEIGAESLKLQLDGVKSMLRTADERTEQEIKARRDVQEALTEVQKMLGHAEGEVA 1571
                  5556667777776653389**********************998888899*********************************************** PP

        Spc7  245 eleeeiaeaervleeckgwsesevsrlkeevkaleelt.gwkivsls 290 
                  +++++ ++ae  ++e k+ +  ++++ +++ +ale++   w+++ ++
  EEA20456.1 1572 RYRQAAEQAEAAVRELKEDRIPQLEKAQTRCDALEKQQeSWEMTLAE 1618
                  **********************************9865268777665 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.00017
        Spc7  143 gleenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesid.keeLeelreelaelkaeieekkkelaelqeqleeleekiee 238 
                  +l+ ++++l++d ++++k+   +++   + +++++el++++e+l++a++   +++ +e+Le    el++ + e +++k   a+ q++  +lee +++
  EEA20456.1 1674 SLRGKFDKLQDDMANVTKD---VTRDQANARRKEEELTAKYESLRAAYDR--EVKlREKLEIDIGELEKSERETAKLKFIFAQSQQENHRLEELVAS 1765
                  5556666666666666554...3444455667777888888888887765..444488888888888899999999999999999************ PP

        Spc7  239 lkeqkseleeeiaeaervleeckgwsesevsrlkeevk 276 
                  l+++ +e+e++ ++ er  +e +++s+ e++r +++++
  EEA20456.1 1766 LRQESQEHENAASRFEREFNEARESSRMEIQRARTSME 1803
                  ******************************99988765 PP

  == domain 3  score: 12.6 bits;  conditional E-value: 1e-05
        Spc7  155 kelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkel.aelqeqleeleekieelkeqk.seleee 249 
                  ++ Le+ +++++ +   le+e ++le+++e+ +  a+ +++  +  Lee+re+ +++ ae+ + k++  +e ++  +++ +++ e +++  +++ e+
  EEA20456.1 1803 EADLEAANNQVNYIRAGLEAEINRLESQVENVRMDADTMKERYELLLEEARENKDSAIAELTAGKDMAmEEQRKTHDRVLNDLRERHARAlHNASED 1899
                  56899********************************************************987776514555556677777777776651555566 PP

        Spc7  250 iaeaervleeckgwsesevsrlkeevkaleeltgwki 286 
                   ++ e++++e+ + s++ v  l+++v +lee+++++ 
  EEA20456.1 1900 RQRIESYMKEKLDLSNEKVAHLQDRVAHLEEKLEIAK 1936
                  6677889999999******************998875 PP

  == domain 4  score: 4.6 bits;  conditional E-value: 0.0028
        Spc7  218 kkkelaelqeqleeleekieelkeqkseleeeiaeaer 255 
                  +++ +  lq+ql++ e++ieel+e+ se+ +e  ++ +
  EEA20456.1 1982 LRESILVLQDQLQQRESRIEELEEELSEVDKEAPNKIK 2019
                  44555556666666666666666666666665543333 PP

>> PAM2  Ataxin-2 C-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   1.9e-05     0.085       2      18 .]     814     830 ..     813     830 .. 0.87
   2 ?    4.3   0.3    0.0081        36       6      17 ..     871     882 ..     870     883 .. 0.90
   3 ?   -2.5   0.0       1.3   5.6e+03      12      17 ..     891     896 ..     887     897 .. 0.85
   4 ?    0.5   0.2      0.14   6.2e+02       5      17 ..     906     918 ..     903     919 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.9e-05
                 ----SSTTSS----TT- CS
        PAM2   2 kkSkLNPnAkEFVPsfk 18 
                 + S LN++A+EF P+++
  EEA20456.1 814 SLSGLNVEAQEFNPTGS 830
                 6699**********985 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.0081
                 SSTTSS----TT CS
        PAM2   6 LNPnAkEFVPsf 17 
                 +N+ A+ F+Ps+
  EEA20456.1 871 FNVGAPSFTPSS 882
                 7999*******8 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 1.3
                 ----TT CS
        PAM2  12 EFVPsf 17 
                  FVPs 
  EEA20456.1 891 SFVPSA 896
                 5***96 PP

  == domain 4  score: 0.5 bits;  conditional E-value: 0.14
                 -SSTTSS----TT CS
        PAM2   5 kLNPnAkEFVPsf 17 
                 ++N +A+ F P+ 
  EEA20456.1 906 SFNADAPTFNPGA 918
                 69********985 PP

>> Filament  Intermediate filament protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1  10.1    0.0016       7.4     197     274 ..    1535    1612 ..    1473    1624 .. 0.89
   2 ?    1.5  49.6     0.039   1.7e+02      19     268 ..    1643    1947 ..    1640    1953 .. 0.87
   3 ?    5.2   2.4    0.0031        14     222     290 ..    1976    2044 ..    1953    2046 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0016
                  XXXXXXXXXXXXXXXXX-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Filament  197 leelqeaaeknsealrsakeeitelrrqiqsleieleslkkqkasleaqlaeleerleaeleklqeklseleeelaei 274 
                  l ++ e  e++ +a r ++e +te+++++ + e e++ +++++++ ea+++el+e    +lek+q   ++le++ ++ 
  EEA20456.1 1535 LRTADERTEQEIKARRDVQEALTEVQKMLGHAEGEVARYRQAAEQAEAAVRELKEDRIPQLEKAQTRCDALEKQQESW 1612
                  556677788888889999999**************************************************9987655 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.039
                  XXXXXXXXXXXXXXXXXXXXXXX...XXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX... CS
    Filament   19 kVraLEqenkeLeakieeleekk...saevsklkelyekeleelrkqldeltkerarlqleldnlreeledlrkkyekelnkreevEaelkalr... 109 
                  kV + E enk+L+++i +l  +     +++++l+  + k  +++ +  +++t+++a+++   ++l +++e lr+ y++e+++re++E ++ +l    
  EEA20456.1 1643 KVATTEDENKDLRSNIGHLTVRIedsMRARQSLRGKFDKLQDDMANVTKDVTRDQANARRKEEELTAKYESLRAAYDREVKLREKLEIDIGELEkse 1739
                  89999**********99887663233777888999999999999999999*****************************999999999999999999 PP

                  ................................................XXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
    Filament  110 ................................................kdldeatl..arvdLekkvesLkeelaflkkvheeEvkelqkqvseqvl 156 
                                                                  ++     +  ar+ +e+ +e+ ++++++ +   e+E++ l++qv e  +
  EEA20456.1 1740 retaklkfifaqsqqenhrleelvaslrqesqehenaasrferefneaRESSRMEIqrARTSMEADLEAANNQVNYIRAGLEAEINRLESQV-E--N 1833
                  99999999999999999999999999999999999999999999998854444444116789******************************.5..5 PP

                  XXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-HHHHHHHHHHHHHHHHH.HHHHHHHHHHHHHHHHHHHH CS
    Filament  157 vevdaarkld.Lteilkeiraqyeelaeknreeaeewykskleelqeaaeknsealrsakeeitelrrqiqsleie.leslkkqkasleaqlaelee 251 
                  v +da    +  +  l+e r++ ++ +++ ++  +   +++ ++  +  +   e   +a ++ +e r++i+s   e l+   ++ a l++++a lee
  EEA20456.1 1834 VRMDADTMKErYELLLEEARENKDSAIAELTAGKDMAMEEQRKTHDRVLNDLRERHARALHNASEDRQRIESYMKEkLDLSNEKVAHLQDRVAHLEE 1930
                  5555555555477799***************999999999999999999999999999999999*******9766538888888899********** PP

                  HHHHHHHHHHHHHHHHH CS
    Filament  252 rleaeleklqeklsele 268 
                  +le + + ++++ ++ +
  EEA20456.1 1931 KLEIAKSAARAAAQAAQ 1947
                  ***99999998877665 PP

  == domain 3  score: 5.2 bits;  conditional E-value: 0.0031
                  HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Filament  222 rrqiqsleieleslkkqkasleaqlaeleerleaeleklqeklseleeelaeireemarqlreYqeLLd 290 
                  + + q+l+  +  l+ q ++ e++++elee+l++  +++ +k++e ++e++ +re +  ++++ q++++
  EEA20456.1 1976 KISPQALRESILVLQDQLQQRESRIEELEEELSEVDKEAPNKIKERDTEISWLRELLGVRVDDLQDIIN 2044
                  556688999999999***************************************999999888888776 PP

>> FliD_C  Flagellar hook-associated protein 2 C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.6   0.00011       0.5     177     234 ..    1661    1717 ..    1544    1720 .. 0.80
   2 ?    3.9   0.8    0.0068        31     175     224 ..    1796    1845 ..    1725    1847 .. 0.78
   3 ?   -0.8   0.1      0.19   8.5e+02     176     225 ..    1885    1933 ..    1847    1948 .. 0.59
   4 ?   -0.8   0.1      0.19   8.3e+02     191     223 ..    1981    2013 ..    1964    2046 .. 0.64

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00011
                  HHHHHHHHHSTT.SHHHHHHHHXXXXHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH CS
      FliD_C  177 lenllksyvkssngtlqtasknltkqikdldkkiedldkrletleerlkkqfaaleka 234 
                  l+  +++ ++++ ++l+++ ++l++++ +++k+++  + +++ +ee+l++++++l  a
  EEA20456.1 1661 LTVRIEDSMRAR-QSLRGKFDKLQDDMANVTKDVTRDQANARRKEEELTAKYESLRAA 1717
                  445578888888.99**************************************99766 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.0068
                  HHHHHHHHHHHSTT.SHHHHHHHHXXXXHHHHHHHHHHHHHCHHHHHHHH CS
      FliD_C  175 trlenllksyvkssngtlqtasknltkqikdldkkiedldkrletleerl 224 
                  +r + +++  +++ n++++     l+ +i++l++++e++ + ++t +er+
  EEA20456.1 1796 QRARTSMEADLEAANNQVNYIRAGLEAEINRLESQVENVRMDADTMKERY 1845
                  45566677777888888999999999999999999999999999988888 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 0.19
                  HHHHHHHHHHSTT.SHHHHHHHHXXXXHHHHHHHHHHHHHCHHHHHHHHH CS
      FliD_C  176 rlenllksyvkssngtlqtasknltkqikdldkkiedldkrletleerlk 225 
                    e +++ + ++s +  q  ++ ++++++  ++k+++l++r+  lee+l+
  EEA20456.1 1885 LRERHARALHNAS-EDRQRIESYMKEKLDLSNEKVAHLQDRVAHLEEKLE 1933
                  3333444444444.555566666666777777788888888888888875 PP

  == domain 4  score: -0.8 bits;  conditional E-value: 0.19
                  HHHHHHHHXXXXHHHHHHHHHHHHHCHHHHHHH CS
      FliD_C  191 tlqtasknltkqikdldkkiedldkrletleer 223 
                  +l++++  l++q+++ +++ie+l+++l++  ++
  EEA20456.1 1981 ALRESILVLQDQLQQRESRIEELEEELSEVDKE 2013
                  444444455555555555555555555555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2252 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1551  (0.0865079); expected 358.6 (0.02)
Passed bias filter:                      419  (0.02337); expected 358.6 (0.02)
Passed Vit filter:                        99  (0.00552178); expected 17.9 (0.001)
Passed Fwd filter:                        52  (0.00290033); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 2.03u 0.42s 00:00:02.44 Elapsed: 00:00:00.64
# Mc/sec: 10654.55
//
Query:       EEA20457.1  [L=203]
Description: endosomal cargo receptor (P24), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.7e-47  161.1   0.8    3.2e-47  160.8   0.8    1.0  1  EMP24_GP25L  emp24/gp25L/p24 family/GOLD


Domain annotation for each model (and alignments):
>> EMP24_GP25L  emp24/gp25L/p24 family/GOLD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  160.8   0.8   1.8e-51   3.2e-47       2     182 .]      22     198 ..      21     198 .. 0.92

  Alignments for each domain:
  == domain 1  score: 160.8 bits;  conditional E-value: 1.8e-51
  EMP24_GP25L   2 ltfklpageekCfyeelkkgtlltgsyqvtdgg....aaldvdlsvkdpdgngerlvkkkdresegdfsftakesgeykvCfdnsfstksskkvsfdi 95 
                   +++l+a++++Cf+e+l+k++++t+++qv d++     +l++d+ ++dp g  +r + k  ++s+ d++fta+ +g++ +Cf+n+ +t++sk+vsf++
   EEA20457.1  22 HNIQLKAHSRECFHEKLHKDDKMTVTFQVGDREfggsGNLEIDFWLEDPAG--NRQYFKNSVSSD-DYTFTAQRDGKFVYCFSNEAWTSNSKEVSFNV 116
                  689***************************999999988********6655..777777678888.******************************** PP

  EMP24_GP25L  96 evgseasdykdsakkekletleselkkleekldsikreqkylrereerlrdtnestnsrvvwwsilqllvlvlvavlqvyyLkrfFk 182
                  +    +++   s      e++e+e+++l+e+l ++++eq y+  re+ +r+t+estn rv wwsi+ql +l++ +++qv+ LkrfF+
   EEA20457.1 117 HGIVYVPE---SELA--QEPIEVEVRRLSESLAQVRDEQSYIVVRERVHRNTAESTNARVKWWSIFQLTFLIGEGIFQVWWLKRFFE 198
                  *9776654...4333..379******************************************************************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (203 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       766  (0.0427241); expected 358.6 (0.02)
Passed bias filter:                      540  (0.0301188); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1314.01
//
Query:       EEA20458.1  [L=199]
Description: endosomal cargo receptor (P24), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.5e-47  161.2   0.8    2.9e-47  160.9   0.8    1.0  1  EMP24_GP25L  emp24/gp25L/p24 family/GOLD


Domain annotation for each model (and alignments):
>> EMP24_GP25L  emp24/gp25L/p24 family/GOLD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  160.9   0.8   1.6e-51   2.9e-47       2     182 .]      22     198 ..      21     198 .. 0.92

  Alignments for each domain:
  == domain 1  score: 160.9 bits;  conditional E-value: 1.6e-51
  EMP24_GP25L   2 ltfklpageekCfyeelkkgtlltgsyqvtdgg....aaldvdlsvkdpdgngerlvkkkdresegdfsftakesgeykvCfdnsfstksskkvsfdi 95 
                   +++l+a++++Cf+e+l+k++++t+++qv d++     +l++d+ ++dp g  +r + k  ++s+ d++fta+ +g++ +Cf+n+ +t++sk+vsf++
   EEA20458.1  22 HNIQLKAHSRECFHEKLHKDDKMTVTFQVGDREfggsGNLEIDFWLEDPAG--NRQYFKNSVSSD-DYTFTAQRDGKFVYCFSNEAWTSNSKEVSFNV 116
                  689***************************999999988********6655..777777678888.******************************** PP

  EMP24_GP25L  96 evgseasdykdsakkekletleselkkleekldsikreqkylrereerlrdtnestnsrvvwwsilqllvlvlvavlqvyyLkrfFk 182
                  +    +++   s      e++e+e+++l+e+l ++++eq y+  re+ +r+t+estn rv wwsi+ql +l++ +++qv+ LkrfF+
   EEA20458.1 117 HGIVYVPE---SELA--QEPIEVEVRRLSESLAQVRDEQSYIVVRERVHRNTAESTNARVKWWSIFQLTFLIGEGIFQVWWLKRFFE 198
                  *9776654...4333..379******************************************************************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (199 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       741  (0.0413297); expected 358.6 (0.02)
Passed bias filter:                      532  (0.0296726); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.41
# Mc/sec: 1443.32
//
Query:       EEA20459.1  [L=221]
Description: acyl-CoA dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.9e-19   68.3   0.0    7.7e-19   67.7   0.0    1.3  1  Acyl-CoA_dh_M  Acyl-CoA dehydrogenase, middle domain
      7e-09   36.0   0.1    1.1e-08   35.4   0.1    1.2  1  Acyl-CoA_dh_1  Acyl-CoA dehydrogenase, C-terminal domain
  ------ inclusion threshold ------
      0.086   13.5   0.0       0.45   11.2   0.0    2.1  2  Acyl-CoA_dh_N  Acyl-CoA dehydrogenase, N-terminal domain


Domain annotation for each model (and alignments):
>> Acyl-CoA_dh_M  Acyl-CoA dehydrogenase, middle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.7   0.0   1.3e-22   7.7e-19       1      94 [.      32     127 ..      32     130 .. 0.94

  Alignments for each domain:
  == domain 1  score: 67.7 bits;  conditional E-value: 1.3e-22
                    EEE---SS-SS-GGG---EE.EEETT.EEEEEEEEEEEETTTT-SEEEEEEETS---.----EEEEEEE..GGGEEE-----BSS-TTS-EEEEEE CS
  Acyl-CoA_dh_M   1 afalTEpqaGsdvasvktta.aerdggeyvlnGeKiwitnaaiatlalvlartekpd.rarglslflvprdapgvsvrrieeklGlrglptgelvf 94 
                    ++a+TEp+aGsdva+++t a ++ d +ey++n +K witn+ + ++ ++ +rt+ p   a glsl++vp + p vs+r+i+++l  r ++++++ +
     EEA20459.1  32 CLAITEPDAGSDVANITTVAeKSADAKEYIINRTKKWITNGIWVEHSTMAVRTGPPGsDAAGLSLLVVPLNYPSVSMRPIKDQLQPRATRQAHVAL 127
                    9*****************9999999999************************7777788************************9999999999876 PP

>> Acyl-CoA_dh_1  Acyl-CoA dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.4   0.1   1.8e-12   1.1e-08      23     113 ..     120     212 ..     116     219 .. 0.90

  Alignments for each domain:
  == domain 1  score: 35.4 bits;  conditional E-value: 1.8e-12
                    SHHHHHHHHHHHHHHHTSB-CC-BGGGSHHHHHHHHHHHHHHHHHHHHHHHHHH--------......HHHHHHHHHHHHHHHHHHHHHHHHHHGG CS
  Acyl-CoA_dh_1  23 lglarraleealeyarrrkafgkplidhqlvreklaemaaeleaarllvyraaealdagkpd......raeasmaKlfaselaqevadlamqllGg 112
                     + a+ al +a +y+ +r+af kp    ++vr++la+ a+e+e++  ++++   ++ + k+       +  ++m+K++a  +++e+ + a+ l+Gg
     EEA20459.1 120 TRQAHVALSTASDYVLKREAFSKP----PVVRHRLAKAATEVESLSTWIEQFLFQMTKLKKVdgdrelGGLMAMVKVKAGMVLNECSQTAILLFGG 211
                    5678899***************98....*********************9998877776666677899***************************9 PP

                    G CS
  Acyl-CoA_dh_1 113 a 113
                    +
     EEA20459.1 212 N 212
                    7 PP

>> Acyl-CoA_dh_N  Acyl-CoA dehydrogenase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   7.5e-05      0.45      89     112 ..       4      27 ..       1      28 [. 0.90
   2 ?   -0.6   0.0      0.34     2e+03      52      74 ..     181     204 ..     144     220 .. 0.60

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 7.5e-05
                    THHHHHHHS-HHHHHHHHHHHHTT CS
  Acyl-CoA_dh_N  89 vapailrfGteeqkrryLpklasg 112
                    ++p++++++++e ++r Lp+l++g
     EEA20459.1   4 GVPPLVKHASPELQERVLPDLLTG 27 
                    6799******************99 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.34
                    GGGTS--.S-HHHHHHHHHHHHHH CS
  Acyl-CoA_dh_N  52 eeygGag.ldyleaaivaeelara 74 
                     e gG+  +  + a +v+ e++++
     EEA20459.1 181 RELGGLMaMVKVKAGMVLNECSQT 204
                    566665424466777777777653 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (221 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      318  (0.0177366); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.38u 0.22s 00:00:00.60 Elapsed: 00:00:00.36
# Mc/sec: 1816.82
//
Query:       EEA20460.1  [L=655]
Description: vacuolar endopolyphosphatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    5.5e-10   40.1   2.5    9.5e-10   39.3   2.5    1.4  1  Metallophos  Calcineurin-like phosphoesterase


Domain annotation for each model (and alignments):
>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.3   2.5   5.3e-14   9.5e-10       2     201 ..      51     319 ..      50     322 .. 0.65

  Alignments for each domain:
  == domain 1  score: 39.3 bits;  conditional E-value: 5.3e-14
                  EEEEEESBTB................TTCCTHHHHHH.................HHHHHHHHHTTESEEEEEST...SSSSS................ CS
  Metallophos   2 rilvigDlHl................algggqlddll.................kllddllreekpdlvllaGD...lvdrg................ 47 
                  ++l+i+D Hl                ++g+g+  +l                  +++++ lr+ k+d+v+++GD                        
   EEA20460.1  51 KFLHITDFHLdrfyvpgsstdedevcHHGNGNAGYLGapgsecdspellvdqtfEWINKNLRD-KVDFVIWTGDsarH---Dnderiprtenqveeln 144
                  89************************6666666666666666666666666444555555666.**********6551...24556686555555444 PP

                  .HHHHHHHHHHHHHHHH.............TSEEEEEC-TTSCHHH.HHHHHHHHHHHH..HHHHEHHHCEEETSEEEEEETTEEEEEEEESE..CEE CS
  Metallophos  48 .dlekellellaalvky.............pipvylllGNHegfee.ellnkygylgif..sepwrsdaevfnnlplaslgsgslkvlllhGg..spe 126
                   ++ ++++        +              +p+++  GN +  +  ++++k ++  +   s++w+       ++p  +      +  ++ Gg  +  
   EEA20460.1 145 aVIANKFI--------EvfshrsdhpdealIVPIIPNIGNND-IMPhNIFEKGPNRWTEklSHLWE------AFIPEEQ------RHTFVEGGyfY-- 219
                  43333344........144444555777776799********.55556666655422223345554......5566666......66677777431.. PP

                  E.....THHHHHHHHHHHSCHHHHCC............HHHHHH..HHHHTTCSEEEEEESSESSCSSSCSCCHHHHH....HHHHHTTESEE...EE CS
  Metallophos 127 l.....lvsldklgslnleleapepg............dewlkd..lekrekadwvivlgHsplyrgsgylfgdeale....dllkkygvdlv...is 198
                           + +l++l +++ ++  +             ewl+   +  re++   i++gH+p+ r++ ++ +de +      +l +y+ d+v   ++
   EEA20460.1 220 TevipnKLAVFSLNTLYFFDSNQAVDgcakksepgyhqMEWLRVqlQLLRERGMKAILIGHVPPARSADKQAWDETCWqkytLWLLQYR-DVVvstFY 316
                  2345553445555555555555555556666666699999999999*******************55555555555557**75577777.33334599 PP

                  ESS CS
  Metallophos 199 GHt 201
                  GH 
   EEA20460.1 317 GHM 319
                  996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (655 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1716  (0.0957109); expected 358.6 (0.02)
Passed bias filter:                      705  (0.0393218); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.69u 0.30s 00:00:00.99 Elapsed: 00:00:00.42
# Mc/sec: 4633.33
//
Query:       EEA20461.1  [L=340]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.9e-15   56.2   0.1    4.9e-14   52.2   0.0    2.4  3  adh_short     short chain dehydrogenase
    4.7e-06   26.6   0.1    8.5e-06   25.8   0.1    1.4  1  KR            KR domain
    1.6e-05   24.6   0.0    3.3e-05   23.6   0.0    1.5  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.2   0.0   8.2e-18   4.9e-14       1     138 [.      23     175 ..      23     181 .. 0.85
   2 ?    0.9   0.0     0.044   2.6e+02     167     188 ..     234     255 ..     224     260 .. 0.85
   3 ?   -2.3   0.0      0.43   2.6e+03      15      43 ..     269     298 ..     268     331 .. 0.71

  Alignments for each domain:
  == domain 1  score: 52.2 bits;  conditional E-value: 8.2e-18
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHT.......TSEEEEEE-TTTSHHHHHHHHHHHHHHH....SSESEEEE---S CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvv.vdrseekleevakelkee.......gakalaiqvDvtdreevealvekavkkl....gkldvLvnNAGi 87 
                 ++vlvtG   GIG+++ ++ ++ Ga+ ++   r+ ek e++ + + ++       ++++ ++q+D+++ ++v ++v+++++ +     +ld  + NAG+
  EEA20461.1  23 QTVLVTGSNTGIGLETTRHAVSLGASKIImGVRTVEKGEKAREDILSKlpegksaKTSIEVWQLDMSSFQSVMTFVQRMKDYItlpgNRLDTAILNAGL 121
                 58***********************9999556788888887777665555446556679********************999899999*********** PP

                 S--SSGGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHH.....HCTTEEEEEEEEGG CS
   adh_short  88 tgsgpfselseeewervievNltgvflltravlpaml.....kqssGrIvnvsSva 138
                    + + +ls + we  i+vN  ++ ll+ ++lp ++     + s+ + v vsS  
  EEA20461.1 122 --ASGVWQLSPDGWEIQIQVNGLSTALLSLELLPILIssassSPSRPHLVIVSSDM 175
                 ..678889***************************997666556666777777765 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.044
                 HGGGTEEEEEEEESSBSSHHHH CS
   adh_short 167 laptgirvnavaPGlvdTdmak 188
                  a++++ v++ +PG++++++  
  EEA20461.1 234 AAQEKVIVTSATPGFCKSELLS 255
                 57888************99875 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 0.43
                 HHHHHHHHTT-EEEE.EESCHHHHHHHHHH CS
   adh_short  15 aiakelakeGakvvv.vdrseekleevake 43 
                 a + + a++Gak +v ++ +++   +++++
  EEA20461.1 269 AACARTAADGAKAIVdAAVRQDGHGKWLEN 298
                 567778888888888666666655555554 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   0.1   1.4e-09   8.5e-06       2      76 ..      24     102 ..      23     121 .. 0.86

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 1.4e-09
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHH....HHHHHHHTT-EEEE----TT-HHHHHHHHHHHH CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedska....liaelealgaevevvaaDvsdkdavealleeik 76 
                 t+l+tG   g+Gle++r+ ++ ga+++++  R+ ++ e++++    ++ e ++  +++ev ++D s+ ++v + ++++k
  EEA20461.1  24 TVLVTGSNTGIGLETTRHAVSLGASKIIMGVRTVEKGEKAREdilsKLPEGKSAKTSIEVWQLDMSSFQSVMTFVQRMK 102
                 78*******************************85555554333337788888999****************9999987 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.6   0.0   5.6e-09   3.3e-05       4     120 ..      32     159 ..      29     186 .. 0.79

  Alignments for each domain:
  == domain 1  score: 23.6 bits;  conditional E-value: 5.6e-09
                   TSHHHHHHHHHHHTT-EEEEEESSGGH..HHHHHHHHHHTT....SE..E..EE--TTSHHHHHHHHHHHHHHH....SSEEEEEE-----EGCSS- CS
  adh_short_C2   4 sgIGraiAkalaeeGaevvltdlneea..kkrveelaeelg....ae..v..lecDVtdeeqvealveevvekf....gklDilvnnagiapklkgp 86 
                    gIG ++ +++ + Ga+ +++ ++  +  +k+ e++ ++l+    a+  +   ++D ++ ++v ++v+++++ +    ++lD ++ nag a      
    EEA20461.1  32 TGIGLETTRHAVSLGASKIIMGVRTVEkgEKAREDILSKLPegksAKtsIevWQLDMSSFQSVMTFVQRMKDYItlpgNRLDTAILNAGLASG---- 124
                   79**************966666655444678888888887754442234266*******************99988989************99.... PP

                   GGGH-HHHHHHHHHHHTHHHHHHHHHHHH.HCTSC CS
  adh_short_C2  87 fletsreefdraldvnlyslfllakaalp.lmkeg 120
                   + ++s ++++  ++vn  s++ll+ ++lp l+ + 
    EEA20461.1 125 VWQLSPDGWEIQIQVNGLSTALLSLELLPiLISSA 159
                   9****************************544433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (340 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       406  (0.0226449); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.47
# Mc/sec: 2182.81
//
Query:       EEA20462.1  [L=168]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.7e-47  158.9   0.2    8.6e-47  158.7   0.2    1.0  1  DUF3237   Protein of unknown function (DUF3237)


Domain annotation for each model (and alignments):
>> DUF3237  Protein of unknown function (DUF3237)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  158.7   0.2   4.8e-51   8.6e-47       1     149 []       5     165 ..       5     165 .. 0.96

  Alignments for each domain:
  == domain 1  score: 158.7 bits;  conditional E-value: 4.8e-51
                 --EEEEEEEEEEE---EEEEEET..EEEEEEEEEEEEEES.....TT--EEE-ST-EEEEEE-T.TS-EEEEEEEEEEETTS-EEEEEEEEEEE--GGG CS
     DUF3237   1 Pslepaftlevkleapvpigegp..gkrnivpitgGtikg.....prldgevlpgGaDwiridp.ggtarldaryvlktddgaliyirytGvvtldeev 91 
                 P+l+paft++v+++ap p+g++   +++ +vp++gGt+ +     p+l++++ ++G+D+ir dp g+++rl+a+ vlkt+d+aliy++y+G+v+l+e v
  EEA20462.1   5 PTLKPAFTVRVSVDAPFPVGSHHrkTSLVVVPMVGGTVISepgftPALNAKFEGTGNDYIRNDPdGKRMRLNAHGVLKTHDDALIYLHYQGTVNLTEGV 103
                 9********************77789**************************************999******************************** PP

                 HHHHHHT-..---GGG-E.EEEEEEEEESSGGGGGGGSS-EEEEEEEESS.E....EEEEEEEE CS
     DUF3237  92 lavlgggekkesspteyg.frthptfetgdekykwLnnavfvGsgrfrve.g....veykvyev 149
                  ++l+g++   +s t++g ++th+ +etgde+yk L+n vfvG+g+f  + g    veykv++v
  EEA20462.1 104 IKALSGQA--GDSETPFGdSFTHFDLETGDERYKDLENGVFVGQGHFVTKtGektiVEYKVSQV 165
                 ******88..6788**********************************8875799*******98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (168 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       336  (0.0187406); expected 358.6 (0.02)
Passed bias filter:                      316  (0.0176251); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.24s 00:00:00.63 Elapsed: 00:00:00.40
# Mc/sec: 1272.87
//
Query:       EEA20463.1  [L=132]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.9e-36  124.5   0.3    3.2e-36  124.4   0.3    1.0  1  DUF3237   Protein of unknown function (DUF3237)


Domain annotation for each model (and alignments):
>> DUF3237  Protein of unknown function (DUF3237)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  124.4   0.3   1.8e-40   3.2e-36      31     149 .]       1     129 [.       1     129 [. 0.96

  Alignments for each domain:
  == domain 1  score: 124.4 bits;  conditional E-value: 1.8e-40
                 EEEEEEES.....TT--EEE-ST-EEEEEE-T.TS-EEEEEEEEEEETTS-EEEEEEEEEEE--GGGHHHHHHT-..---GGG-E.EEEEEEEEESSGG CS
     DUF3237  31 itgGtikg.....prldgevlpgGaDwiridp.ggtarldaryvlktddgaliyirytGvvtldeevlavlgggekkesspteyg.frthptfetgdek 122
                 ++gGt+ +     p+l++++ ++G+D+ir dp g+++rl+a+ vlkt+d+aliy++y+G+v+l+e v ++l+g++   +s t++g ++th+ +etgde+
  EEA20463.1   1 MVGGTVISepgftPALNAKFEGTGNDYIRNDPdGKRMRLNAHGVLKTHDDALIYLHYQGTVNLTEGVIKALSGQA--GDSETPFGdSFTHFDLETGDER 97 
                 5799999999999*******************999**************************************88..6788****************** PP

                 GGGGGSS-EEEEEEEESS.E....EEEEEEEE CS
     DUF3237 123 ykwLnnavfvGsgrfrve.g....veykvyev 149
                 yk L+n vfvG+g+f  + g    veykv++v
  EEA20463.1  98 YKDLENGVFVGQGHFVTKtGektiVEYKVSQV 129
                 ****************8875799*******98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (132 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       334  (0.018629); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.24s 00:00:00.64 Elapsed: 00:00:00.42
# Mc/sec: 943.50
//
Query:       EEA20464.1  [L=435]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.2e-08   33.0   0.1    7.7e-08   32.1   0.1    1.4  1  14-3-3    14-3-3 protein


Domain annotation for each model (and alignments):
>> 14-3-3  14-3-3 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.1   0.1   4.3e-12   7.7e-08     135     214 ..     246     325 ..     242     330 .. 0.93

  Alignments for each domain:
  == domain 1  score: 32.1 bits;  conditional E-value: 4.3e-12
                 HHHHHHHHHHHHHHHHTTTGCC-HHHHHHHHHHHHHHHCTT--HHHHHHHHHHHHHCCHCCCCCS.TTTHHHHHHHHHHH CS
      14-3-3 135 aekakeaYeeAleiakkelqpthpirLglaLNySVflyeilnspekAcelakkafdeaiaeldelseesykdstlilqlL 214
                 ++ a+ ++++A ++a++ l+ +hp+rL++ L+y+ +ly+ l++ +   +lak+++ +  ++ + +++es +d+  ++ +L
  EEA20464.1 246 TQTATPCFSHAATLADTLLPGSHPLRLSVKLEYAAYLYDCLHDADACRRLAKQTIADVYNAQEGMDDESFEDAAELVAVL 325
                 67888999****************************************************************99998887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (435 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       602  (0.0335769); expected 358.6 (0.02)
Passed bias filter:                      343  (0.019131); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.30s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 2883.73
//
Query:       EEA20465.1  [L=256]
Description: 3-ketoacyl-acyl carrier protein reductase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.3e-57  194.3   0.3    2.8e-57  194.0   0.3    1.0  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
    5.7e-47  159.7   0.1    7.5e-47  159.3   0.1    1.1  1  adh_short     short chain dehydrogenase
      4e-11   43.2   0.1    5.9e-11   42.6   0.1    1.1  1  KR            KR domain
    0.00011   21.8   0.1    0.00045   19.8   0.1    2.0  1  Epimerase     NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  194.0   0.3   6.3e-61   2.8e-57       1     234 []      15     254 ..      15     254 .. 0.94

  Alignments for each domain:
  == domain 1  score: 194.0 bits;  conditional E-value: 6.3e-61
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTT.....SEE..EE--TTSHHHHHHHHHHHHHHH..SSEEEEEE-----EGCSS-GG CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneeakkrveelaeelg.....aev..lecDVtdeeqvealveevvekf..gklDilvnnagiapklkgpfl 88 
                   G  +gIG+++A ++a++Ga+vv+t+ +e++ ++++++ ++l      +++  +++D +  +   ++++++ + f  +++ ilvnnag   +  +++ 
    EEA20465.1  15 GSSRGIGEGLAVEFARRGAKVVVTYTSESSSAKADNILSRLAdykygRSAitVQADLRTMDGPSQVIAATIKAFpdEGISILVNNAGCEVQ--KRLS 109
                   5679**************************8888888887664434333248**********************999*************9..**** PP

                   GH-HHHHHHHHHHHTHHHHHHHHHHHHHCTSCCEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTTH CS
  adh_short_C2  89 etsreefdraldvnlyslfllakaalplmkeggsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikgf 185
                   e++ e+++ ++d n+++++l+++a+lp++++ g+i+n+ svga+ ++p+y+ y+ +Kaa+e++tr++A+elg +g +vN+v pgp++T++  +i+  
    EEA20465.1 110 EATVEDLAYVHDLNVRGTMLMTQAVLPHLRRPGRIINIGSVGARAGFPGYSLYASSKAAIEGFTRCWAAELGVDGHTVNCVNPGPVDTDMIYQIN-- 204
                   **********************************************************************************************8.. PP

                   HHHHHHHHHHSTTSS.-B-HHHHHHHHHHHCSGGGTT--SEEEEESTTGG CS
  adh_short_C2 186 delleelearaplgr.lgtpeevaeaalfLasdeasyitGqtlvvDgGlt 234
                   +++ e+ ++++p+++ l+t++++a++++fLa ++++++tGqt+ + gG+t
    EEA20465.1 205 PAIVEAQKKSTPVEQrLATVDDIAQICAFLAEERSRWVTGQTISASGGWT 254
                   999999999999875388******************************97 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  159.3   0.1   1.7e-50   7.5e-47       1     191 [.       9     204 ..       9     207 .. 0.93

  Alignments for each domain:
  == domain 1  score: 159.3 bits;  conditional E-value: 1.7e-50
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEE...EESCHHHHHHHHHHHHHT..TSEEEEEE-TTTSHHHHHHHHHHHHHHH..SSESEEEE---SS--SS CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvv...vdrseekleevakelkee..gakalaiqvDvtdreevealvekavkkl..gkldvLvnNAGitgsgp 92 
                 kv+++tG s+GIG  +a e+a++Gakvvv    ++s++k+ ++++ l +   g++a+++q+D+++++  ++++++ +k +  +++ +LvnNAG + ++ 
  EEA20465.1   9 KVAIITGSSRGIGEGLAVEFARRGAKVVVtytSESSSAKADNILSRLADYkyGRSAITVQADLRTMDGPSQVIAATIKAFpdEGISILVNNAGCEVQKR 107
                 89***************************422233455666777777777999***************************999**************** PP

                 GGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHHC CS
   adh_short  93 fselseeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakelr 191
                  se + e+   v ++N+ g++l+t+avlp++  ++ GrI+n++Sv ++ +++g++ Y++sKaa++g+tr++a el  +g +vn+v+PG+vdTdm  +++
  EEA20465.1 108 LSEATVEDLAYVHDLNVRGTMLMTQAVLPHL--RRPGRIINIGSVGARAGFPGYSLYASSKAAIEGFTRCWAAELGVDGHTVNCVNPGPVDTDMIYQIN 204
                 ******************************5..59***********************************************************87766 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.6   0.1   1.3e-14   5.9e-11       4     165 ..      12     178 ..      10     193 .. 0.91

  Alignments for each domain:
  == domain 1  score: 42.6 bits;  conditional E-value: 1.3e-14
                 EEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHT..T-EEEE----TT-HHHHHHHHHHHHHHS..S---EEEE---------TT CS
          KR   4 litGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaeleal..gaevevvaaDvsdkdavealleeikaee..ppikGvihaAgvlrdklle 98 
                 +itG   g+G  la   a++ga+ +v  + + ++++++++ +++l+++  g +  +v+aD+   d  ++++++  + +  + i+  ++ Ag   +k l+
  EEA20465.1  12 IITGSSRGIGEGLAVEFARRGAKVVVTYTSE-SSSAKADNILSRLADYkyGRSAITVQADLRTMDGPSQVIAATIKAFpdEGISILVNNAGCEVQKRLS 109
                 8**********************99988887.678888889****997568899*****************99999998889***************** PP

                 T--HHHHHHHHTTTTHHHHHHHHHTTT..S--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHH CS
          KR  99 emtaedleqvlapKvkGawnLhelled..esldffvlfSSiagllgsagqanYaaaNaflDalaeyrrs 165
                 e t edl+ v    v+G+  + +++ +  ++   ++ + S+++  g +g + Ya+  a ++++ + +++
  EEA20465.1 110 EATVEDLAYVHDLNVRGTMLMTQAVLPhlRRPGRIINIGSVGARAGFPGYSLYASSKAAIEGFTRCWAA 178
                 ***********************99988999999*****************************998764 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.1     1e-07   0.00045       2     172 ..      12     192 ..      11     248 .. 0.77

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 1e-07
                 EEETTTSHHHHHHHHHHHHCTSE.EEEEES-STTTTCHHCHHC..........EEEE--TT-HH.......HHHHHHHHHT-SEEEE--S.---HH... CS
   Epimerase   2 lVtGatGfiGsalvkallekgye.vigldrlssasntarledl..........elveldltdrs.......alerlfkeeqpdavihlAa.vggva... 78 
                 ++tG +  iG  l+ +++++g + v++ +++ss+ +  ++               v++dl+  +       a+ ++f +e++ + ++ A+ +   +   
  EEA20465.1  12 IITGSSRGIGEGLAVEFARRGAKvVVTYTSESSSAKADNILSRladykygrsaITVQADLRTMDgpsqviaATIKAFPDEGISILVNNAGcEVQKRlse 110
                 89*******************996666677766666555555589********66666666666666667799***************99877665111 PP

                 HHHHSHHHHHHHHTHHHHHHHHHHHHH..TCTEEEEEEEGGGGTSCSSSSBSTCSTTS----SSHHHHHHHHHHHHHHHHHHHHT-EEEEEEESEE CS
   Epimerase  79 assedpadfieknlqgtlnlleaarka..gvkrllflsSsevYGkdaeqpkeettltgplkpnspYaaaKlageklveayaaqyglnaiilrlfnl 172
                 a++ed a++ + n++gt+ + +a+  +   + r+++++S    G+ a            ++  s Ya +K+a+e  ++ +aa+ g++  ++++ n 
  EEA20465.1 111 ATVEDLAYVHDLNVRGTMLMTQAVLPHlrRPGRIINIGS---VGARAG-----------FPGYSLYASSKAAIEGFTRCWAAELGVDGHTVNCVNP 192
                 556677777779*************8854555*******...676666...........455689******************9*99999999985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (256 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       527  (0.0293937); expected 358.6 (0.02)
Passed bias filter:                      488  (0.0272185); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.41
# Mc/sec: 1862.65
//
Query:       EEA20466.1  [L=315]
Description: CORD and CS domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.9e-52  173.5  19.9    1.6e-27   96.0   7.4    2.3  2  CHORD     CHORD
    8.2e-14   52.4   0.0    1.4e-13   51.7   0.0    1.4  1  CS        CS domain
  ------ inclusion threshold ------
       0.01   16.4   0.6        8.8    6.9   0.0    3.1  3  AXH       Ataxin-1 and HBP1 module (AXH)
        4.1    7.3  13.7        7.3    6.5   1.0    3.6  2  BTK       BTK motif


Domain annotation for each model (and alignments):
>> CHORD  CHORD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.4   4.6     3e-27   1.3e-23       1      63 []       3      61 ..       3      61 .. 0.95
   2 !   96.0   7.4   3.5e-31   1.6e-27       2      62 ..     131     191 ..     130     193 .. 0.96

  Alignments for each domain:
  == domain 1  score: 83.4 bits;  conditional E-value: 3e-27
                EE--SBTT--EE-STT--TT-.EEEB---EEEETTEEEETTTTEEESSHHHHTT----EEE-- CS
       CHORD  1 lkCknkGCgkkfeeeeneeeaeCtyHpgapvfheglkgWsCCkkkvldFdeFlkiegCttgkH 63
                +kC +kGCgk f++ e+     C yHpg+pvfheg+kgW+CCk +vl FdeFl+i++CttgkH
  EEA20466.1  3 TKCVHKGCGKVFTDLEE----DCIYHPGPPVFHEGQKGWKCCKPRVLTFDEFLTIPPCTTGKH 61
                69***********6655....4****************************************9 PP

  == domain 2  score: 96.0 bits;  conditional E-value: 3.5e-31
                 E--SBTT--EE-STT--TT-.EEEB---EEEETTEEEETTTTEEESSHHHHTT----EEE- CS
       CHORD   2 kCknkGCgkkfeeeeneeeaeCtyHpgapvfheglkgWsCCkkkvldFdeFlkiegCttgk 62 
                 +C++kGC++++++++++++++C++Hpg+p+fheg+kgWsCCk++vl+FdeF+ki+gC+++k
  EEA20466.1 131 TCRRKGCNATYNPDASRDSETCEHHPGQPIFHEGSKGWSCCKRRVLEFDEFMKIPGCKEKK 191
                 8********************************************************9875 PP

>> CS  CS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.7   0.0   3.1e-17   1.4e-13       1      76 []     210     286 ..     210     286 .. 0.92

  Alignments for each domain:
  == domain 1  score: 51.7 bits;  conditional E-value: 3.1e-17
                 SSCEEEEETTEEEEEEE-TTCTTTTTCEEEEEETTEEEEEE..TS.CEEEEECEBSS-BETTTEEEEEETTEEEEEEEB CS
          CS   1 vkydWyQtldeVvvtiyvkkvnikkkdvkvefkerslkvki..gk.eklliegeLfgpIdpeesswtieskkveitLkK 76 
                 v++d+yQt ++++ ++y+kk+  +k++ kv+f+e+++++ +   + +++++  +LfgpIdpe ss++i ++k++++L K
  EEA20466.1 210 VRTDFYQTATTINASLYLKKI--DKEKAKVTFTENTVEFDLptTDnKRFIKTFNLFGPIDPEASSYSIFGTKMDFKLAK 286
                 589*****************9..*****************98745578887777***********************99 PP

>> AXH  Ataxin-1 and HBP1 module (AXH)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0     0.086   3.9e+02      83      92 ..      34      43 ..      24      51 .. 0.79
   2 ?    6.9   0.0     0.002       8.8      56      90 ..     137     172 ..     123     175 .. 0.81
   3 ?    4.2   0.0     0.014        61      15      62 ..     205     248 ..     197     260 .. 0.74

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.086
         AXH 83 gkGWsSfsPs 92
                +kGW +++P+
  EEA20466.1 34 QKGWKCCKPR 43
                79*******7 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.002
         AXH  56 lkltfsvgeekekvtvecslehPfFvk.gkGWsSfs 90 
                  + t++++  +++ t e +  +P F + +kGWs+++
  EEA20466.1 137 CNATYNPDASRDSETCEHHPGQPIFHEgSKGWSCCK 172
                 56788899999999*********9987369****97 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.014
         AXH  15 kkvedlktedflqsaesse.dlkLkestverieeeeskksavlkltfsv 62 
                 +kved++t+ f q+a++++  l Lk++ +e+ + + +++    +++f++
  EEA20466.1 205 EKVEDVRTD-FYQTATTINaSLYLKKIDKEKAKVTFTEN----TVEFDL 248
                 58****986.99998887779999999998888776433....345554 PP

>> BTK  BTK motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   1.0    0.0016       7.3       2      16 ..      23      41 ..      22      44 .. 0.78
   2 ?    3.2   5.7     0.017        78       6      17 ..     161     173 ..     154     190 .. 0.70

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0016
         BTK  2 YHPg..afvggk..WlCCk 16
                YHPg  +f +g   W CCk
  EEA20466.1 23 YHPGppVFHEGQkgWKCCK 41
                8888775666666*****8 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.017
         BTK   6 afvggk.WlCCkq 17 
                 ++ g k W+CCk 
  EEA20466.1 161 FHEGSKgWSCCKR 173
                 4455558****96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (315 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       650  (0.0362541); expected 358.6 (0.02)
Passed bias filter:                      470  (0.0262145); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 2055.52
//
Query:       EEA20467.1  [L=102]
Description: hypothetical protein PMAA_043030 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.7e-14   54.0   0.1      2e-14   53.8   0.1    1.1  1  DUF836        Glutaredoxin-like domain (DUF836)
     0.0025   18.0   0.1      0.004   17.4   0.1    1.4  1  Glutaredoxin  Glutaredoxin


Domain annotation for each model (and alignments):
>> DUF836  Glutaredoxin-like domain (DUF836)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.8   0.1   2.2e-18     2e-14       1      79 [.      14      95 ..      14      98 .. 0.91

  Alignments for each domain:
  == domain 1  score: 53.8 bits;  conditional E-value: 2.2e-18
                -EEEEE-TT-HHHHHHHHHHHHHCCCTTEEEEEEETT..T-CCCHCCCCTTTTEEEECTTCGGB..TCCECGCCB-HHHHHH CS
      DUF836  1 kltLyskpgChlCeqakekLkelkleegleleviDIa..kdeeleakYgleipvlalegvkktss.lleelswrldeeqLaa 79
                +ltL+++ +C+lC+ ak  L++l+ +  ++  ++DI   +++++++ Y+ ++pvl++++ ++  +  l +l +r++e ++++
  EEA20467.1 14 RLTLFTRAQCGLCDTAKLTLSKLQQRRTFRYTEVDIMvpENKKWKDVYEFDVPVLHVQPATSDDEsKLRKLFHRFSESEVEK 95
                59***********************************999999****************88765547899999999998876 PP

>> Glutaredoxin  Glutaredoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.1   4.4e-07     0.004       2      32 ..      16      50 ..      15      67 .. 0.85

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 4.4e-07
                  EEEESTSSHHHHHHHHHHHHTT....GGEEEEEGC CS
  Glutaredoxin  2 vlftkptCpyCkkakrlLkelg....vkfeeidvd 32
                  +lft+ +C+ C  ak +L +l     ++++e+d++
    EEA20467.1 16 TLFTRAQCGLCDTAKLTLSKLQqrrtFRYTEVDIM 50
                  79****************88886666778888886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (102 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       716  (0.0399353); expected 358.6 (0.02)
Passed bias filter:                      525  (0.0292822); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.39u 0.24s 00:00:00.63 Elapsed: 00:00:00.39
# Mc/sec: 781.16
//
Query:       EEA20468.1  [L=997]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   4.7e-230  764.6   0.4   5.7e-230  764.3   0.4    1.1  1  DUF3405   Protein of unknown function (DUF3405)


Domain annotation for each model (and alignments):
>> DUF3405  Protein of unknown function (DUF3405)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  764.3   0.4  3.2e-234  5.7e-230       1     517 []     433     972 ..     433     972 .. 0.95

  Alignments for each domain:
  == domain 1  score: 764.3 bits;  conditional E-value: 3.2e-234
     DUF3405   1 cfdRfgRygpYGlgeskkegglgvgeegekegsekvweektekvdwrkvdWgelqerCleaNkeRFkeleekeakkekeakeaeekeekekeaekekke 99 
                 cfdRfgR+gpYGlg+  ++gg+g+g+eg++egs++vw++  + vd+r+++W+++q+rC+ aN++RF++l +++ +++ ++        ++ +a+ e+  
  EEA20468.1 433 CFDRFGRLGPYGLGYGARKGGSGAGMEGDREGSDRVWDD-VPPVDFREINWAAAQNRCVIANSHRFAKLGDHHLDRAFAMPVG-----ASPKAHLESPP 525
                 **************************************7.****************************766665554433322.....34445556666 PP

     DUF3405 100 eeeeeekeekkkkkRtAvvlRtwtgykyteedilnlRalisElsLksGGeYevhllvhvkdeelpiwadeetyqkvleeavpeEfrglatLwsekqmes 198
                 + e+e+ + +++ +RtAv++Rtw++++yteedi++lRali+ElsL +GGe++v +l+hvkd++l+iw+deety++vl++a+p+Efrg+ +Lwse+qm++
  EEA20468.1 526 APEKERVKGTDHLPRTAVLVRTWHDFHYTEEDIMYLRALITELSLMTGGEFTVLFLIHVKDDNLQIWSDEETYDRVLQDALPKEFRGMGILWSERQMNL 624
                 777778999****************************************************************************************** PP

     DUF3405 199 lYpgleeesftrdlevhgvyrsaflplqlFaqqhpeydyfWnwEmDvRytGhyyelldklsefakkqpRkglweRnerfYipsvhGswedFtqavekqt 297
                 +Y gle esf+r l+vhgvyrs+f+p+q+F++ hpeydy+WnwEmDvR+tGh+y+++dk +++a++qpRkglweRn+rfY+psvhG w+dF+++v++qt
  EEA20468.1 625 IYGGLE-ESFERGLPVHGVYRSTFMPVQYFSHLHPEYDYVWNWEMDVRHTGHWYHFFDKAASWARQQPRKGLWERNSRFYVPSVHGPWDDFMHTVRVQT 722
                 ******.78****************************************************************************************** PP

     DUF3405 298 ee............................kgektvwGpvrvkevkpl....gpkpptseeedkyewGvgEeADlitlnpifdpeettWvlrddvtgyk 364
                 e                             +ge+ +wGpvr +e + +    +++ppts+e+dkyewGvgEeADl+++np+fdpe+ttW+lr+dvtgy 
  EEA20468.1 723 ELgtnspnnlwsavkdsedksdpnhkdhgrHGEDFIWGPVRPHESDVMelelDVTPPTSMEKDKYEWGVGEEADLLVFNPLFDPEGTTWLLRNDVTGY- 820
                 *99**************************************544444444559*********************************************. PP

     DUF3405 365 neteakppRraaiitasrlSrrLLeamheetarkkhtmfsEmvpatvALhhGlKavyaphpvyvdrkwplealekvfnagrkgasggartsvfgkereh 463
                 n+++++p RraaiitasrlSrrLL++mh+et  k+h+mfsEm+pat+ALhhGlKavy+ph+vy+drkwp++++e+vfnagr+gasggartsvfg+ reh
  EEA20468.1 821 NREDGMPERRAAIITASRLSRRLLTTMHRETSMKRHSMFSEMWPATTALHHGLKAVYVPHSVYIDRKWPTRYVEAVFNAGRNGASGGARTSVFGD-REH 918
                 8888*******************************************************************************************.*** PP

     DUF3405 464 nlkgltwyynsefaeelyrrwlglkeeneGgeeeeeeeegrmclpsmllhpvKe 517
                 n++g+tw+y+++f+++lyrrwlg+k++n+Gge+ee ++egr+clp+m+lhpvK+
  EEA20468.1 919 NFRGTTWFYSAGFPSNLYRRWLGYKVDNDGGEKEELAGEGRLCLPPMMLHPVKD 972
                 *****************************************************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (997 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       378  (0.0210832); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.27s 00:00:00.95 Elapsed: 00:00:00.42
# Mc/sec: 7198.27
//
Query:       EEA20469.1  [L=626]
Description: flavin-binding monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.4e-26   91.6   0.0    5.2e-24   85.0   0.0    2.2  2  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
    9.9e-21   73.7   0.0    1.1e-18   67.0   0.0    2.3  2  FMO-like        Flavin-binding monooxygenase-like
    2.1e-19   69.9   0.0    2.9e-15   56.3   0.0    2.3  2  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    1.7e-15   57.0   0.7    8.3e-12   44.9   0.8    3.1  2  K_oxygenase     L-lysine 6-monooxygenase (NADPH-requiring)
      8e-10   38.5   0.4    4.3e-06   26.2   0.2    3.0  3  FAD_binding_3   FAD binding domain
    1.1e-09   38.8   0.2     0.0098   16.4   0.0    3.6  3  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
    3.2e-09   36.4   0.3     0.0012   18.2   0.0    2.3  2  2-Hacid_dh_C    D-isomer specific 2-hydroxyacid dehydrogenase
    6.4e-07   29.5   0.0      2e-05   24.7   0.0    2.6  2  NAD_binding_8   NAD(P)-binding Rossmann-like domain
    2.8e-06   27.4   0.2       0.57   10.1   0.0    4.0  4  NAD_binding_9   FAD-NAD(P)-binding
    1.6e-05   24.1   0.0     0.0054   15.8   0.0    3.5  4  Lycopene_cycl   Lycopene cyclase protein
    1.7e-05   24.5   0.0       0.03   13.9   0.0    2.6  2  ApbA            Ketopantoate reductase PanE/ApbA
    2.6e-05   24.6   0.0      0.012   16.1   0.0    2.7  2  NAD_binding_7   Putative NAD(P)-binding
    3.1e-05   24.0   0.1      0.078   12.9   0.1    2.4  2  3HCDH_N         3-hydroxyacyl-CoA dehydrogenase, NAD binding 
    3.7e-05   23.0   0.0       0.03   13.4   0.0    3.1  3  GIDA            Glucose inhibited division protein A
    3.9e-05   24.1   0.0        3.3    8.4   0.0    3.6  3  F420_oxidored   NADP oxidoreductase coenzyme F420-dependent
    6.1e-05   21.9   0.0      0.021   13.6   0.0    3.1  3  HI0933_like     HI0933-like protein
    0.00016   21.3   0.0     0.0034   17.0   0.1    2.3  2  IlvN            Acetohydroxy acid isomeroreductase, NADPH-bin
    0.00019   20.7   0.0     0.0077   15.4   0.1    2.8  3  FAD_binding_2   FAD binding domain
     0.0002   21.4   0.0       0.24   11.5   0.0    2.5  2  Shikimate_DH    Shikimate / quinate 5-dehydrogenase
    0.00053   19.3   0.0       0.13   11.6   0.0    2.2  2  AlaDh_PNT_C     Alanine dehydrogenase/PNT, C-terminal domain
    0.00064   19.4   1.7       0.22   11.0   0.1    2.7  2  DAO             FAD dependent oxidoreductase
     0.0017   18.6   1.9       0.56   10.5   0.0    3.1  2  TrkA_N          TrkA-N domain
     0.0029   17.8   0.1        2.2    8.4   0.1    2.5  2  NAD_binding_2   NAD binding domain of 6-phosphogluconate dehy
     0.0053   16.2   0.2       0.19   11.1   0.1    2.7  2  FAD_oxidored    FAD dependent oxidoreductase
     0.0098   15.2   0.2        2.6    7.2   0.0    3.5  4  Thi4            Thi4 family
  ------ inclusion threshold ------
      0.014   15.9   0.0       0.49   10.9   0.0    2.4  2  XdhC_C          XdhC Rossmann domain
      0.025   14.6   0.0       0.96    9.4   0.0    2.7  2  NAD_Gly3P_dh_N  NAD-dependent glycerol-3-phosphate dehydrogen
      0.043   13.2   0.0        2.6    7.4   0.0    2.3  2  ThiF            ThiF family
      0.052   13.0   0.0         10    5.5   0.0    2.3  2  adh_short       short chain dehydrogenase
       0.28   10.9   0.9       0.71    9.6   0.2    1.8  2  ELFV_dehydrog   Glutamate/Leucine/Phenylalanine/Valine dehydr


Domain annotation for each model (and alignments):
>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.0   0.0   8.7e-27   5.2e-24       1     197 [.     213     410 ..     213     420 .. 0.84
   2 ?    4.3   0.0     0.033        20     222     276 ..     509     559 ..     500     581 .. 0.64

  Alignments for each domain:
  == domain 1  score: 85.0 bits;  conditional E-value: 8.7e-27
  Pyr_redox_3   1 iIiGaGPaGlaaaielkkagledylilEkg.nignsiyrypkemtfispsftsekleipdlnaiseetspafslkeeklsrkealeYlrevaksfelp 97 
                  +I+GaG aGl+ a  l+ +g+ + l ++++ +ig+   +++k+ +++++  + e   +  l++  ++  p+f        ++++ ++++++a+  el+
   EEA20469.1 213 LIVGAGQAGLNLAARLQSLGV-STLLVDRHeRIGD---NWRKRYRTLTTHDPAEFTHMAYLPFPKNW--PQF------TPKDKLGDWFEAYASLMELN 298
                  6********************.6789999978886...78889999998888888888888877654..544......4578899************* PP

  Pyr_redox_3  98 iklfeeVesvkkedeg..fevetske.....tyeAkkviiAtGefdkPnklnipGeek...lvkhyskvkefhkya..gqkvvViGgknSavDaAlel 183
                  + ++++V s + +d++   +v+ +k      t++ k+v+ AtG  + P+++ ++G++k   +v h s+ +++++y   g+kv+V+G +nS+ D+A ++
   EEA20469.1 299 VWTNTSVVSAAYDDNTsiWTVTVRKPdgferTLHPKHVVFATGHSGEPKVPTFQGQQKfrgTVYHGSQHRDASEYDvrGKKVIVVGTGNSGHDIAENF 396
                  *******9999865433499999984445569*************************875555666677777766555******************** PP

  Pyr_redox_3 184 vrkgaeVtvvtrgs 197
                  +++ga+Vt++ r+ 
   EEA20469.1 397 YENGADVTMLQRRG 410
                  **********9985 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.033
  Pyr_redox_3 222 vkeekikvlfnaevkeikekeeeykvktedgkkvevkddvvlatGykpdlsflkk 276
                  ++e+kikv++    + ike +  +++  +dgk++e+ d vvlatG+++  + ++k
   EEA20469.1 509 IAEGKIKVHKS--PDGIKEFTP-HTMILADGKELEA-DMVVLATGFDNMRTTVRK 559
                  55565665554..555665544.3556777788775.778899999887777766 PP

>> FMO-like  Flavin-binding monooxygenase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.0   0.0   1.9e-21   1.1e-18       6     221 ..     214     415 ..     209     422 .. 0.79
   2 ?    4.4   0.0     0.017        10     291     330 ..     509     550 ..     500     566 .. 0.83

  Alignments for each domain:
  == domain 1  score: 67.0 bits;  conditional E-value: 1.9e-21
    FMO-like   6 viGaGvsGlasikccleegleptcfersddiGGlwrfkenveeGrasiyksvvsnsskemscfsdfplpedypnflhnsklleylklfakefdllkyiq 104
                 ++GaG +Gl         g+     +r + iG  wr          + y+++ +    e +  +  p+p+++p f +++kl ++++++a  ++l  +  
  EEA20469.1 214 IVGAGQAGLNLAARLQSLGVSTLLVDRHERIGDNWR----------KRYRTLTTHDPAEFTHMAYLPFPKNWPQFTPKDKLGDWFEAYASLMELNVW-- 300
                 555555555544444455555555556666665555..........459999999999**99***************************99998644.. PP

    FMO-like 105 fkttvcsvkkrpdfstsGqwevvtekegkkesavf.davmvctGhhvnphlplesfpGiekfkGqyfhsrdykepevf..kgkrvlviGlGnsggdiav 200
                  +t v+s     d  ++  w v+ +k +  e+++    v+  tGh  +p++p  +f G +kf+G ++h  ++++ + +  +gk+v+v+G Gnsg dia 
  EEA20469.1 301 TNTSVVSA--AYDD-NTSIWTVTVRKPDGFERTLHpKHVVFATGHSGEPKVP--TFQGQQKFRGTVYHGSQHRDASEYdvRGKKVIVVGTGNSGHDIAE 394
                 45555554..4444.4568**988876666666652789999*********9..6****************99998763369***************** PP

    FMO-like 201 elsrtaeqvllstrsGswvls 221
                 +  ++ ++v +  r+G++v+s
  EEA20469.1 395 NFYENGADVTMLQRRGTYVIS 415
                 *******************98 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.017
    FMO-like 291 ilaGavkvkss...vkeltetsaifedgtveedidvvifatGy 330
                 i  G++kv+ s   +ke+t  + i+ dg    + d+v++atG+
  EEA20469.1 509 IAEGKIKVHKSpdgIKEFTPHTMILADGKEL-EADMVVLATGF 550
                 667999998654559************9765.57********8 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.3   0.0   4.8e-18   2.9e-15       2     182 ..     211     417 ..     210     424 .. 0.76
   2 !   11.3   0.0   0.00025      0.15     209     239 ..     523     552 ..     492     592 .. 0.67

  Alignments for each domain:
  == domain 1  score: 56.3 bits;  conditional E-value: 4.8e-18
                  SEEEE--SHHHHHHHHHHHHHTS-EEEEETTHCHHHCSHHHHCHHHHHHHHHHHHH...........................HHHHCHHHHCCCCHC CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...........................xxxxxxxxxxxxxxx RF
  Pyr_redox_2   2 dvvviGgGpAGlaaaltlaqagakvtlvelegtclnggcllskallgvaedaeias...........................evvkklnqgielllg 72 
                   v+++G+G AGl++a +l+  g+ ++lv+ + +  ++     +  l + ++ae  +                                l  ++ + ++
   EEA20469.1 211 TVLIVGAGQAGLNLAARLQSLGVSTLLVD-RHERIGDNWRKRYRTLTTHDPAEFTHmaylpfpknwpqftpkdklgdwfeayaS----LM-ELNVWTN 302
                  699*************************4.444444444444444444444444445567777777778899989888854431....22.3445555 PP

                  CTCEEEEESCEEEEETEEEC...TCEEEEEESEEEE---.E.EE-BCTCTTC.TTBEECCSECHHHHHHCCSS-TSEEEEES-SHHHHHHHHHHHHHT CS
                  xxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxx.x.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  73 eevvkidpgkkkvklekkke...gdeekiaydklvlAtG.s.sprdlgipGvaenvgklvrtldsaealklkllpkrivvvGgGyiGvElAaalaklg 165
                  ++vv+  ++  +   + +++   g e+++  +++v AtG s +p+ ++ +G ++  g++ + +++ +a +++ + k+++vvG G+ G ++A  + + g
   EEA20469.1 303 TSVVSAAYDDNTSIWTVTVRkpdGFERTLHPKHVVFATGhSgEPKVPTFQGQQKFRGTVYHGSQHRDASEYDVRGKKVIVVGTGNSGHDIAENFYENG 400
                  6677777666444333333344588999999********7359999**************************************************** PP

                  -EEEEEESSSSSSTTS- CS
                  xxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 166 kevtlveardrllrald 182
                  ++vt++++r + + ++d
   EEA20469.1 401 ADVTMLQRRGTYVISVD 417
                  *******9987765555 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00025
                  EEETTEEEEEEETTSCEEEESEEEE-S-EEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 209 idgngeklevvledgeeidadlvvvavGvrp 239
                  i++ +  ++++l dg+e++ad+vv+a+G+  
   EEA20469.1 523 IKEFTP-HTMILADGKELEADMVVLATGFDN 552
                  332222.446777777777777777777654 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.9   0.8   1.4e-14   8.3e-12      99     227 ..     285     411 ..     210     424 .. 0.83
   2 ?    5.8   0.0     0.011       6.6     268     341 ..     479     551 ..     452     552 .. 0.72

  Alignments for each domain:
  == domain 1  score: 44.9 bits;  conditional E-value: 1.4e-14
  K_oxygenase  99 edYlrWvasqleeqvrfgeeveevepdeeeeeelltveskdaegeeeelearnlvlgvG..tepkiPevleklegkervvHsseylerkeellakkri 194
                   d+ +  as +e +v  +++v +  +d+++  +++tv++++++g e++l+ +++v ++G  +epk+P++  + + + +v+H s+     e + ++k++
   EEA20469.1 285 GDWFEAYASLMELNVWTNTSVVSAAYDDNT--SIWTVTVRKPDGFERTLHPKHVVFATGhsGEPKVPTFQGQQKFRGTVYHGSQHRDASEYDVRGKKV 380
                  455555566666567778888888888875..79*************************8889******9999999*************99******* PP

  K_oxygenase 195 aVvGsGqSaaeifedllrrqkkvelklvtrsea 227
                  +VvG G S+ +i+e+ +++ +  +++++ r+  
   EEA20469.1 381 IVVGTGNSGHDIAENFYENGA--DVTMLQRRGT 411
                  ****************99987..7888888765 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.011
  K_oxygenase 268 nykgvdaelieelyeelyeqkvkgeerlrllpnrevesaeaegkgeveltlrneesgeeetlevdavvlATGYr 341
                   ykg+d++ i++ly +     + +    +l+++ +++ ++++++g  e+t +     + ++le+d+vvlATG++
   EEA20469.1 479 VYKGIDESGIARLYMTRGGGYYIDVGCSQLIAEGKIK-VHKSPDGIKEFTPHTMILADGKELEADMVVLATGFD 551
                  5677777777777766666555555666777777765.55555566677777777788899***********96 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.2   0.2   7.2e-09   4.3e-06       3      36 ..     211     244 ..     209     259 .. 0.89
   2 ?    0.5   0.0      0.48   2.9e+02     103     166 ..     280     344 ..     244     358 .. 0.71
   3 !    7.9   0.0    0.0026       1.6       3      38 ..     379     414 ..     378     427 .. 0.90

  Alignments for each domain:
  == domain 1  score: 26.2 bits;  conditional E-value: 7.2e-09
                    EEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSS CS
  FAD_binding_3   3 dVlIVGaGpaGlmlallLseaGvrvvlvekrstt 36 
                    +VlIVGaG aGl la  L++ Gv+++lv+++++ 
     EEA20469.1 211 TVLIVGAGQAGLNLAARLQSLGVSTLLVDRHERI 244
                    79*****************************975 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.48
                    -HHHHHHHHHHHHHHHTEEETCSEEEECCEECC.CCCCCEEEECCTTEEEEEEEEEEEE--GTT- CS
  FAD_binding_3 103 pqteleriLvehaeerglqvrfktevesleqde.egvtaevrdketgeeetvrakYlvGaDGgrS 166
                    p ++l    ++ a+   l+v  +t v+s   d+ +++ ++   k +g e+t++ k +v a G  +
     EEA20469.1 280 PKDKLGDWFEAYASLMELNVWTNTSVVSAAYDDnTSIWTVTVRKPDGFERTLHPKHVVFATGHSG 344
                    5555555555556666678888888777665550555555567789999*********9988755 PP

  == domain 3  score: 7.9 bits;  conditional E-value: 0.0026
                    EEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCC CS
  FAD_binding_3   3 dVlIVGaGpaGlmlallLseaGvrvvlvekrsttvv 38 
                    +V++VG+G +G   a    e G +v+++ +r t v 
     EEA20469.1 379 KVIVVGTGNSGHDIAENFYENGADVTMLQRRGTYVI 414
                    69****************************988765 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0   1.6e-05    0.0098       2      35 ..     212     245 ..     211     257 .. 0.91
   2 ?    2.7   0.0      0.31   1.8e+02      42      79 ..     284     322 ..     279     326 .. 0.84
   3 !   15.2   0.1     4e-05     0.024       1      33 [.     379     411 ..     379     420 .. 0.91

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 1.6e-05
                 EEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSS CS
   Pyr_redox   2 vvvvGgGyiglElAgalaelgkkVtvversdkll 35 
                 v++vG+G  gl lA+ l+ lg ++ +v+r++++ 
  EEA20469.1 212 VLIVGAGQAGLNLAARLQSLGVSTLLVDRHERIG 245
                 89*****************************998 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.31
                 HHHHHHHHHHHTTEEEECSEEEEEEEEETTS.EEEEEEE CS
   Pyr_redox  42 askilqeklekngievllntkveeiegsedg.vesvklk 79 
                 ++++++ + + +  +v++nt+v++   ++++ + +v+++
  EEA20469.1 284 LGDWFEAYASLMELNVWTNTSVVSAAYDDNTsIWTVTVR 322
                 6789999999999************99999877667765 PP

  == domain 3  score: 15.2 bits;  conditional E-value: 4e-05
                 EEEEECSSHHHHHHHHHHHHTTSEEEEEESSSS CS
   Pyr_redox   1 kvvvvGgGyiglElAgalaelgkkVtvversdk 33 
                 kv+vvG G++g + A+++ e g++Vt+++r+ +
  EEA20469.1 379 KVIVVGTGNSGHDIAENFYENGADVTMLQRRGT 411
                 79***************************9976 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0     2e-06    0.0012      21      73 ..     193     246 ..     186     264 .. 0.82
   2 !   15.8   0.1   1.2e-05    0.0069      15      69 ..     354     410 ..     348     424 .. 0.83

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 2e-06
                   TCC.HTTCCGSBS-GTTSEEEEES-SHHHHHHHHHHHHTT-EEEEESSSHHHHH CS
  2-Hacid_dh_C  21 gew.ksekallgkelsgktvGiiGlGrIGqavakrlkafgmkviaydrskkkee 73 
                   g+w +++++    e  + tv i+G+G+ G ++a rl+++g+  + +dr+++  +
    EEA20469.1 193 GTWkERREKAVKFEGVEPTVLIVGAGQAGLNLAARLQSLGVSTLLVDRHERIGD 246
                   678666667777788899******************************988655 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 1.2e-05
                   HHHHHTTCC..HTTCCGSBS-GTTSEEEEES-SHHHHHHHHHHHHTT-EEEEESSSH CS
  2-Hacid_dh_C  15 deevregew..ksekallgkelsgktvGiiGlGrIGqavakrlkafgmkviaydrsk 69 
                   +++ r   +  +++++ + ++++gk+v ++G+G+ G+ +a+ + + g++v++ +r+ 
    EEA20469.1 354 QQKFRGTVYhgSQHRDASEYDVRGKKVIVVGTGNSGHDIAENFYENGADVTMLQRRG 410
                   55555555565677888999******************************9999875 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.0   3.4e-08     2e-05       1      36 [.     214     249 ..     214     268 .. 0.90
   2 ?    1.8   0.0      0.47   2.8e+02       1      28 [.     382     409 ..     382     412 .. 0.93

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 3.4e-08
                    EE--SHHHHHHHHHHHCCTEEEEEE-SSSSSSGGG- CS
  NAD_binding_8   1 IvGaGlsGlvaAylLakagfdvlllekrdrlGGraa 36 
                    IvGaG +Gl +A++L+  g++ ll+++++r+G +++
     EEA20469.1 214 IVGAGQAGLNLAARLQSLGVSTLLVDRHERIGDNWR 249
                    9*******************************7765 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.47
                    EE--SHHHHHHHHHHHCCTEEEEEE-SS CS
  NAD_binding_8   1 IvGaGlsGlvaAylLakagfdvlllekr 28 
                    +vG+G sG  +A    ++g+dv+ l++r
     EEA20469.1 382 VVGTGNSGHDIAENFYENGADVTMLQRR 409
                    8***********************9987 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.1   0.0   0.00096      0.57       2      61 ..     214     266 ..     213     300 .. 0.82
   2 ?    3.2   0.0      0.13        79     117     155 ..     297     342 ..     274     343 .. 0.65
   3 ?   -1.0   0.0       2.6   1.5e+03       2      20 ..     382     400 ..     381     423 .. 0.83
   4 !    9.3   0.0    0.0018       1.1     135     154 ..     530     549 ..     498     551 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00096
  NAD_binding_9   2 ivGaGprGlavlerLlarakkkspleitlfdpsepgagrvwrtdqseelllNvpasemsl 61 
                    ivGaG +Gl +++rL +       ++  l+d++e   g  wr++  ++l ++ pa+ +++
     EEA20469.1 214 IVGAGQAGLNLAARLQSL-----GVSTLLVDRHERI-GDNWRKR-YRTLTTHDPAEFTHM 266
                    9**************999.....59999****9998.9999999.567888888877766 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.13
  NAD_binding_9 117 vevh.raevvdleeradg....qavlladg..aslaadaVvLAlGh 155
                    ++v  +++vv+ + ++++    ++v++ dg  ++l+ ++Vv A+Gh
     EEA20469.1 297 LNVWtNTSVVSAAYDDNTsiwtVTVRKPDGfeRTLHPKHVVFATGH 342
                    44432556776666665534224666678877889**********9 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 2.6
  NAD_binding_9   2 ivGaGprGlavlerLlara 20 
                    +vG G +G  ++e++ ++ 
     EEA20469.1 382 VVGTGNSGHDIAENFYENG 400
                    8************999885 PP

  == domain 4  score: 9.3 bits;  conditional E-value: 0.0018
  NAD_binding_9 135 avlladgaslaadaVvLAlG 154
                    +++ladg++l+ad VvLA+G
     EEA20469.1 530 TMILADGKELEADMVVLATG 549
                    6789***************9 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   9.1e-06    0.0054       2      36 ..     212     244 ..     211     259 .. 0.88
   2 ?   -1.1   0.0       1.3   7.8e+02     127     165 ..     328     367 ..     293     375 .. 0.67
   3 ?    1.1   0.0      0.28   1.6e+02       2      27 ..     380     405 ..     379     431 .. 0.85
   4 ?    1.8   0.0      0.16        97     118     149 ..     527     554 ..     510     593 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 9.1e-06
  Lycopene_cycl   2 vvviGaGpAglslAarlteakpglkvvlieaspsl 36 
                    v+++GaG Agl lAarl  +  g++ +l++  + +
     EEA20469.1 212 VLIVGAGQAGLNLAARL--QSLGVSTLLVDRHERI 244
                    89***************..**********977665 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 1.3
  Lycopene_cycl 127 grkirarlvvdarglaslk..karrlglQtfyGvevevdnp 165
                    +r+++ + vv a+g  s++   +   g Q+f+G + + +++
     EEA20469.1 328 ERTLHPKHVVFATGH-SGEpkVPTFQGQQKFRGTVYHGSQH 367
                    35999999999*994.4443245557999****99887766 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.28
  Lycopene_cycl   2 vvviGaGpAglslAarlteakpglkv 27 
                    v+v+G G  g  +A++  e+ +++ +
     EEA20469.1 380 VIVVGTGNSGHDIAENFYENGADVTM 405
                    89**************9666666555 PP

  == domain 4  score: 1.8 bits;  conditional E-value: 0.16
  Lycopene_cycl 118 geslvvleggrkirarlvvdarglaslkkarr 149
                    +  +++l++g++++a +vv a+g + +   +r
     EEA20469.1 527 TPHTMILADGKELEADMVVLATG-FDN---MR 554
                    5568899****************.433...33 PP

>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   0.0   5.1e-05      0.03       1      48 [.     212     262 ..     212     285 .. 0.83
   2 !    7.8   0.0    0.0041       2.4       1      32 [.     380     412 ..     380     440 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 5.1e-05
                 EEEES-SHHHHHHHHHHHHHTHCEEEE-SCHHHHH.HHHHCEEEEETT..C CS
        ApbA   1 iailGaGaiGsllaakLakagadvtlilrsrrlea.lkknGlrltseg..g 48 
                 ++i+GaG  G  laa+L+  g    l++r +r+ + ++k+  +lt+++  +
  EEA20469.1 212 VLIVGAGQAGLNLAARLQSLGVSTLLVDRHERIGDnWRKRYRTLTTHDpaE 262
                 68*****************************77777***999999998641 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0041
                 EEEES-SHHHHHHHHHHHHHTHCEEEE-SCH.H CS
        ApbA   1 iailGaGaiGsllaakLakagadvtlilrsr.r 32 
                 + ++G+G  G  +a + +++gadvt++ r+   
  EEA20469.1 380 VIVVGTGNSGHDIAENFYENGADVTMLQRRGtY 412
                 579**************************9833 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   0.0     0.041        25       9      39 ..     211     241 ..     203     319 .. 0.65
   2 !   16.1   0.0     2e-05     0.012       4      40 ..     374     410 ..     373     481 .. 0.74

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.041
  NAD_binding_7   9 kvlvvGgGevAarkvrklleagakvtvvape 39 
                    +vl+vG+G+ +++ + +l + g    +v+  
     EEA20469.1 211 TVLIVGAGQAGLNLAARLQSLGVSTLLVDRH 241
                    79****************9999999999887 PP

  == domain 2  score: 16.1 bits;  conditional E-value: 2e-05
  NAD_binding_7   4 dlkgkkvlvvGgGevAarkvrklleagakvtvvapev 40 
                    d++gkkv+vvG G+ +   ++++ e+ga+vt++  + 
     EEA20469.1 374 DVRGKKVIVVGTGNSGHDIAENFYENGADVTMLQRRG 410
                    799****************************987765 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.6   0.0    0.0027       1.6       2      43 ..     212     253 ..     211     265 .. 0.88
   2 !   12.9   0.1   0.00013     0.078       1      31 [.     379     409 ..     379     421 .. 0.91

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0027
                 EEEE--SCCHHHHHHHHHHTT-EEEEE-S-HHHHHHHHHHHH CS
     3HCDH_N   2 vaviGaGtmGagiaavfasagleVvlvdiseealekalekie 43 
                 v ++GaG+ G  +aa + s g+++ lvd++e++ ++ +++ +
  EEA20469.1 212 VLIVGAGQAGLNLAARLQSLGVSTLLVDRHERIGDNWRKRYR 253
                 889***************************998887777665 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 0.00013
                 EEEEE--SCCHHHHHHHHHHTT-EEEEE-S- CS
     3HCDH_N   1 kvaviGaGtmGagiaavfasagleVvlvdis 31 
                 kv v+G+G  G+ ia+ f ++g +V++++++
  EEA20469.1 379 KVIVVGTGNSGHDIAENFYENGADVTMLQRR 409
                 689************************9876 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.0   4.9e-05      0.03       2      29 ..     212     249 ..     211     270 .. 0.75
   2 ?    4.5   0.0     0.026        15       1      33 [.     379     411 ..     379     419 .. 0.87
   3 ?    0.7   0.0      0.36   2.1e+02     130     149 ..     530     549 ..     515     563 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 4.9e-05
                 EEEE-SSHHHHHHHHHHHHTT--EEEE..........E CS
        GIDA   2 viViGgGhAGceAAlaaarlGakvlLi..........t 29 
                 v ++G+G AG+  A+ +  lG+++lL+           
  EEA20469.1 212 VLIVGAGQAGLNLAARLQSLGVSTLLVdrherigdnwR 249
                 89************************966555555550 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.026
                 CEEEE-SSHHHHHHHHHHHHTT--EEEEES-GG CS
        GIDA   1 dviViGgGhAGceAAlaaarlGakvlLithkld 33 
                 +viV+G G +G   A +  + Ga+v++++ +  
  EEA20469.1 379 KVIVVGTGNSGHDIAENFYENGADVTMLQRRGT 411
                 69*************************966554 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 0.36
                 EEEETTS-EEEECEEEE--T CS
        GIDA 130 gvvtedgetikakavviatG 149
                  ++++dg++++a+ vv+atG
  EEA20469.1 530 TMILADGKELEADMVVLATG 549
                 568899************** PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.0     0.017        10       3      57 ..     213     262 ..     211     268 .. 0.79
   2 !    8.4   0.0    0.0055       3.3       2      33 ..     380     408 ..     379     416 .. 0.83
   3 ?    4.5   0.0     0.089        53      16      81 ..     506     560 ..     496     568 .. 0.75

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.017
                    EEETTSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC-EEECECHHH CS
  F420_oxidored   3 giiGaGnmgealasgllaagaqpheivvansrnpekaeelaeelgvkvtavdnee 57 
                     i+GaG+ g  la +l++ g   + ++ + +r++   + +++++   +t+ d +e
     EEA20469.1 213 LIVGAGQAGLNLAARLQSLG--VSTLL-V-DRHERIGDNWRKRYRTLTTH-DPAE 262
                    588*****************..55565.6.89999999999999755555.6555 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0055
                    EEEETTSHHHHHHHHHHHHTTS-GGCEEEEEE CS
  F420_oxidored   2 igiiGaGnmgealasgllaagaqpheivvans 33 
                    + ++G+Gn g+ +a+++ ++g    ++++  +
     EEA20469.1 380 VIVVGTGNSGHDIAENFYENG---ADVTMLQR 408
                    6678*****************...88876544 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.089
                    HHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC-EEECECHHHHHHH-SEEEE-S-HHHHHHHHHHC CS
  F420_oxidored  16 sgllaagaqpheivvansrnpekaeelaeelgvkvtavdneeaaeeadvvvlavkpedveevlsel 81 
                    s+l+a+g    +i  + +++p+ ++e+  +  + + +   +e + ead+vvla  + ++  +++++
     EEA20469.1 506 SQLIAEG----KIK-V-HKSPDGIKEFTPHTMILADG---KE-L-EADMVVLATGFDNMRTTVRKV 560
                    5677777....777.4.68888888888888766666...33.3.58************9999887 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.6   0.0   3.5e-05     0.021       2      36 ..     211     245 ..     210     249 .. 0.94
   2 ?    3.9   0.0      0.03        18       2      31 ..     379     408 ..     378     413 .. 0.92
   3 ?   -0.1   0.0      0.48   2.9e+02     141     164 ..     529     550 ..     509     566 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 3.5e-05
                  SEEEE--SHHHHHHHHHHHHTT--EEEE-SSSSS- CS
  HI0933_like   2 dviviGgGaAGlmaAisaakrgkrVlllekakklg 36 
                  +v+++G+G AGl  A+++++ g ++ll+++ +++g
   EEA20469.1 211 TVLIVGAGQAGLNLAARLQSLGVSTLLVDRHERIG 245
                  699****************************9998 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.03
                  SEEEE--SHHHHHHHHHHHHTT--EEEE-S CS
  HI0933_like   2 dviviGgGaAGlmaAisaakrgkrVlllek 31 
                  +viv+G G +G   A++  ++g++V++l +
   EEA20469.1 379 KVIVVGTGNSGHDIAENFYENGADVTMLQR 408
                  89************************9976 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.48
                  E.EEEEE.TTEEEEESEEEE---- CS
  HI0933_like 141 gkfrvktkseeeleadklvlAtGG 164
                  +  ++ + +++elead +vlAtG 
   EEA20469.1 529 H--TMILADGKELEADMVVLATGF 550
                  3..3333489************95 PP

>> IlvN  Acetohydroxy acid isomeroreductase, NADPH-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0      0.29   1.8e+02       6      37 ..     211     242 ..     208     268 .. 0.81
   2 !   17.0   0.1   5.7e-06    0.0034       3      38 ..     376     411 ..     374     430 .. 0.88

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.29
                 -EEEES-SHHHHHHHHHHHHTT--EEEEE-TT CS
        IlvN   6 kiaviGyGsqGhaqalnlrdsgldvvvglreg 37 
                 ++ ++G G  G + a  l+  g+   +  r++
  EEA20469.1 211 TVLIVGAGQAGLNLAARLQSLGVSTLLVDRHE 242
                 799*****************999877665555 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 5.7e-06
                 HTS-EEEES-SHHHHHHHHHHHHTT--EEEEE-TT- CS
        IlvN   3 kgkkiaviGyGsqGhaqalnlrdsgldvvvglregs 38 
                 +gkk+ v+G G+ Gh  a+n+ ++g dv++ +r+g+
  EEA20469.1 376 RGKKVIVVGTGNSGHDIAENFYENGADVTMLQRRGT 411
                 79***************************9998886 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.1   1.3e-05    0.0077       2      33 ..     212     243 ..     211     248 .. 0.92
   2 ?    1.2   0.0      0.26   1.6e+02     147     204 ..     288     345 ..     261     364 .. 0.80
   3 ?   -0.7   0.0      0.97   5.8e+02       2      29 ..     380     407 ..     379     412 .. 0.89

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 1.3e-05
                    EEEE--SHHHHHHHHHHHHTTT-EEEEESSSG CS
  FAD_binding_2   2 viViGsGlAGLaAAleaaeaGlkvavvekeqe 33 
                    v+++G+G AGL  A++++  G ++++v+  ++
     EEA20469.1 212 VLIVGAGQAGLNLAARLQSLGVSTLLVDRHER 243
                    9**************************99876 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.26
                    HHHHHHTCTEEEEESEEEEEEEECTT.EEEEEEEEETTTTCEEEEEESEEEE-----GG CS
  FAD_binding_2 147 lvesarkagvdfqerteadeLivedg.rvtGavvenpesgrevrirakavvlatgGfgr 204
                    + ++a  +++ ++++t++++  ++d+  + +++v+ + +g e++++ k+vv atg  g 
     EEA20469.1 288 FEAYASLMELNVWTNTSVVSAAYDDNtSIWTVTVR-KPDGFERTLHPKHVVFATGHSGE 345
                    44555556699************9888999*9999.566777889999*******8886 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 0.97
                    EEEE--SHHHHHHHHHHHHTTT-EEEEE CS
  FAD_binding_2   2 viViGsGlAGLaAAleaaeaGlkvavve 29 
                    viV+G+G +G   A +  e+G++v+++ 
     EEA20469.1 380 VIVVGTGNSGHDIAENFYENGADVTMLQ 407
                    9*********999999999999998876 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.2   0.0    0.0083         5      12      41 ..     209     238 ..     200     258 .. 0.83
   2 !   11.5   0.0    0.0004      0.24       9      44 ..     374     408 ..     367     418 .. 0.87

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0083
                   T-EEEEES-SHHHHHHHHHHHCCT-CEEEE CS
  Shikimate_DH  12 ekkvlliGaGemaelvakhLlakgvkkvvv 41 
                   e +vl++GaG+ +  +a  L + gv  ++v
    EEA20469.1 209 EPTVLIVGAGQAGLNLAARLQSLGVSTLLV 238
                   568*******************99996655 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 0.0004
                   ..TT-EEEEES-SHHHHHHHHHHHCCT-CEEEEEES CS
  Shikimate_DH   9 slkekkvlliGaGemaelvakhLlakgvkkvvvaNR 44 
                   ++++kkv+++G+G+ ++ +a++++++g++ v+ + R
    EEA20469.1 374 DVRGKKVIVVGTGNSGHDIAENFYENGAD-VTMLQR 408
                   5789***********************99.887777 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.6   0.0   0.00021      0.13      22      62 ..     204     243 ..     198     264 .. 0.86
   2 ?    5.3   0.0     0.017        10      26      62 ..     375     411 ..     360     425 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00021
                  EETCB---EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHH CS
  AlaDh_PNT_C  22 gvpgvepakvlviGgGvaGlqAiatakglgakVtvlDvrpa 62 
                  + +gvep +vl++G+G aGl+ +a  ++lg ++ ++D  ++
   EEA20469.1 204 KFEGVEP-TVLIVGAGQAGLNLAARLQSLGVSTLLVDRHER 243
                  5677777.69**********************999998765 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.017
                  B---EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHH CS
  AlaDh_PNT_C  26 vepakvlviGgGvaGlqAiatakglgakVtvlDvrpa 62 
                  v+  kv+v+G G  G   +++  + ga+Vt+l  r +
   EEA20469.1 375 VRGKKVIVVGTGNSGHDIAENFYENGADVTMLQRRGT 411
                  77889**************************998865 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.1   0.00037      0.22       2      33 ..     212     245 ..     211     271 .. 0.89
   2 !    7.2   0.1    0.0056       3.4     160     232 ..     296     369 ..     256     506 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00037
                 EEEECTSHHHHHHHHHHHHTT..EEEEESSSSTT CS
         DAO   2 vviiGGGiiGlstAyeLarrg..Vtllekgdiag 33 
                 v+i+G+G +Gl  A  L+  g  ++l+++++++g
  EEA20469.1 212 VLIVGAGQAGLNLAARLQSLGvsTLLVDRHERIG 245
                 99***************7779*********9888 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0056
                 T-EEEESECEEEEEEEE.TCEEEEEEECT.EEEE...EEEEEEE--GGGHH.HHHTTCTTTSEEEEEEEEEEEEEECCT CS
         DAO 160 Gveilegtevtgleeed.gkvwgverttp.gend...aadavVnaaGawsd.llgllkeldlpispvrgqvlvlkplse 232
                   ++ ++t v++   +d   +w+v + +p g ++     ++vV a+G+    ++   ++++ + + +rg+v++ ++  +
  EEA20469.1 296 ELNVWTNTSVVSAAYDDnTSIWTVTVRKPdGFERtlhP-KHVVFATGHSGEpKV---PTFQGQ-QKFRGTVYHGSQHRD 369
                 456778999999733335889***96667698843634.77******8866766...555333.667777776633332 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.5   0.0   0.00093      0.56       1      41 [.     212     252 ..     212     264 .. 0.80
   2 ?    6.3   0.1     0.018        11       1      29 [.     380     408 ..     380     425 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00093
                 EEEES-SHHHHHHHHHHHH.TTEEEEEEESSHHHHHHHHHTT CS
      TrkA_N   1 iiiiGlGrvGrslaeeLse.ggkdvvvidkdeerveelreeg 41 
                 ++i+G+G+ G +la +L++ g  + +++d+ e+  ++ r++ 
  EEA20469.1 212 VLIVGAGQAGLNLAARLQSlGV-STLLVDRHERIGDNWRKRY 252
                 68*****************777.59****9988776666655 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.018
                 EEEES-SHHHHHHHHHHHHTTEEEEEEES CS
      TrkA_N   1 iiiiGlGrvGrslaeeLseggkdvvvidk 29 
                 +i++G G+ G  +ae++ e+g dv+   +
  EEA20469.1 380 VIVVGTGNSGHDIAENFYENGADVTMLQR 408
                 79*****************7767887665 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   0.0     0.012       7.4       4      53 ..     214     264 ..     211     269 .. 0.81
   2 !    8.4   0.1    0.0036       2.2       2      31 ..     380     409 ..     379     427 .. 0.89

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.012
                    EE--SHHHHHHHHHHHHTT-EEEEE-SSHHHHHHHHHTT.EEE-SSHHHHH CS
  NAD_binding_2   4 fiGlGvMGsnmalnllkagykvavynrtkekveelvaeg.akaaesieelv 53 
                    ++G G+ G n+a +l++ g ++ +++r++   +++ ++    ++++++e++
     EEA20469.1 214 IVGAGQAGLNLAARLQSLGVSTLLVDRHERIGDNWRKRYrTLTTHDPAEFT 264
                    79**************************98888887775355556666666 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0036
                    EEEE--SHHHHHHHHHHHHTT-EEEEE-SS CS
  NAD_binding_2   2 igfiGlGvMGsnmalnllkagykvavynrt 31 
                    + ++G+G+ G+ +a+n+ ++g +v++ +r+
     EEA20469.1 380 VIVVGTGNSGHDIAENFYENGADVTMLQRR 409
                    669**********************99986 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.1   0.1   0.00031      0.19       2     143 ..     212     340 ..     211     344 .. 0.62
   2 ?   -1.0   0.0       1.4   8.3e+02       2      32 ..     380     410 ..     379     412 .. 0.94

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00031
  FAD_oxidored   2 vvVvGGgpaGvaAAiaAaraGakvlLveergvlGGlltsglvatdignkaeeqvvtgiareflerlrqrggarlkkrskwntfepevakavleemla 98 
                   v++vG+g aG+  A      G ++lLv++++++G +  +  ++  ++   +++ ++  +  f ++  q             +   + +   +e+  +
    EEA20469.1 212 VLIVGAGQAGLNLAARLQSLGVSTLLVDRHERIGDNWRKRYRTLTTH--DPAEFTHMAYLPFPKNWPQ-------------FTPKDKLGDWFEAYAS 293
                   89*******************************97766666443333..2333444444444444422.............2223345555555555 PP

  FAD_oxidored  99 eagvtvllntrlvevekegkr.iesvtveskeg.rktirAkvfiDAT 143
                     +++v++nt +v++  ++++ i+ vtv++ +g ++t++ k ++ AT
    EEA20469.1 294 LMELNVWTNTSVVSAAYDDNTsIWTVTVRKPDGfERTLHPKHVVFAT 340
                   55666666666666666543346666664444666666666666555 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 1.4
  FAD_oxidored   2 vvVvGGgpaGvaAAiaAaraGakvlLveerg 32 
                   v+VvG g +G   A    ++Ga v ++++rg
    EEA20469.1 380 VIVVGTGNSGHDIAENFYENGADVTMLQRRG 410
                   9**************************9987 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.2   0.0    0.0044       2.6      16      53 ..     208     244 ..     197     249 .. 0.82
   2 ?   -0.7   0.0       1.1   6.6e+02     136     171 ..     300     345 ..     297     352 .. 0.79
   3 ?    2.2   0.0      0.15        89      18      49 ..     378     408 ..     365     413 .. 0.80
   4 ?   -0.4   0.0      0.91   5.4e+02     149     187 ..     531     567 ..     524     586 .. 0.69

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0044
                 TEEEEEEE--SHHHHHHHHHHHHCTTS-EEEEESSSS- CS
        Thi4  16 aesDvvivGaGssGLtaayylakkpdlkvailersvsp 53 
                 +e  v+ivGaG +GL  a  l    ++ +++++r+  +
  EEA20469.1 208 VEPTVLIVGAGQAGLNLAARLQSL-GVSTLLVDRHERI 244
                 67789***********99999887.8888888887655 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 1.1
                 EEEEHHHHTCTTTSS.-B-EEEEEE..........EEEE--GSSST CS
        Thi4 136 vinwtlvelahdtqscvDPlvirak..........vvvdatGhdge 171
                  +n ++v+ a+d+++ +   ++r             vv atGh ge
  EEA20469.1 300 WTNTSVVSAAYDDNTSIWTVTVRKPdgfertlhpkHVVFATGHSGE 345
                 577778888888888887777777777777777779999****986 PP

  == domain 3  score: 2.2 bits;  conditional E-value: 0.15
                 EEEEEE--SHHHHHHHHHHHHCTTS-EEEEES CS
        Thi4  18 sDvvivGaGssGLtaayylakkpdlkvailer 49 
                   v++vG+G sG   a  + ++ +  v++l r
  EEA20469.1 378 KKVIVVGTGNSGHDIAENFYEN-GADVTMLQR 408
                 579*********9999998888.777776665 PP

  == domain 4  score: -0.4 bits;  conditional E-value: 0.91
                 SS.-B-EEEEEEEEEE--GSSSTTTTHHHHHHHHCTTTS CS
        Thi4 149 qscvDPlvirakvvvdatGhdgeivavvvkkikleakie 187
                     D + ++a +vv atG d     ++v+k+   +  +
  EEA20469.1 531 MILADGKELEADMVVLATGFDNM--RTTVRKVLGDKVAD 567
                 5556888999**********963..44455554444444 PP

>> XdhC_C  XdhC Rossmann domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00082      0.49       1      35 [.     212     250 ..     212     321 .. 0.74
   2 ?    2.6   0.0       0.3   1.8e+02       1      65 [.     380     473 ..     380     483 .. 0.67

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00082
                 EEEE--STTHHHHHHHHHHHTEEEEEEES-GGGG....- CS
      XdhC_C   1 lvifGaghvaqalarlaaalgfrvtvvdpreefa....t 35 
                 ++i+Gag+ +  la+ +++lg+++ +vd  e++     +
  EEA20469.1 212 VLIVGAGQAGLNLAARLQSLGVSTLLVDRHERIGdnwrK 250
                 68**************************99976544430 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.3
                 EEEE--STTHHHHHHHHHHHTEEEEEEES-GGGG...........................-GGG-TT-SE.........-EEEE--S-H.HHHHHHHH CS
      XdhC_C   1 lvifGaghvaqalarlaaalgfrvtvvdpreefa...........................tkerfpeade.........tavvvlthdh.klDaeale 62 
                 ++++G g+ ++ +a+   + g +vt+++ r ++                                     +         ++ v lt+   + D+e+l+
  EEA20469.1 380 VIVVGTGNSGHDIAENFYENGADVTMLQRRGTYVisvdkgvfmlnegtydewgppteqadiW--------AeslpyqvafAFNVHLTRRVsEVDKEILD 470
                 689***************************98777777777777666655555444333332........03344445566666666655466666666 PP

                 HHS CS
      XdhC_C  63 aal 65 
                  + 
  EEA20469.1 471 VLA 473
                 655 PP

>> NAD_Gly3P_dh_N  NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.0       0.3   1.8e+02       2      33 ..     212     243 ..     211     265 .. 0.84
   2 ?    9.4   0.0    0.0016      0.96       1      32 [.     379     410 ..     379     419 .. 0.90

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.3
                     EEEE--SHHHHHHHHHHHTTT--EEEE-S-HH CS
  NAD_Gly3P_dh_N   2 iavlGaGswGtalAkvlaenghevrlwvreee 33 
                     + ++GaG+ G  lA+ l++ g ++ l  r+e 
      EEA20469.1 212 VLIVGAGQAGLNLAARLQSLGVSTLLVDRHER 243
                     779****************9999888888774 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.0016
                     -EEEE--SHHHHHHHHHHHTTT--EEEE-S-H CS
  NAD_Gly3P_dh_N   1 kiavlGaGswGtalAkvlaenghevrlwvree 32 
                     k+ v+G+G+ G  +A  + eng +v++ +r+ 
      EEA20469.1 379 KVIVVGTGNSGHDIAENFYENGADVTMLQRRG 410
                     789************************99975 PP

>> ThiF  ThiF family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.0    0.0043       2.6      20      46 ..     211     237 ..     199     244 .. 0.90
   2 ?    3.3   0.0     0.074        44      14      41 ..     373     400 ..     358     406 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0043
                 EEEEE--SHHHHHHHHHHHHHTTTEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        ThiF  20 kvllvGaGglGsellknLalsGvgklt 46 
                 +vl+vGaG  G +l+  L  +Gv+ l 
  EEA20469.1 211 TVLIVGAGQAGLNLAARLQSLGVSTLL 237
                 69*********************9985 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.074
                 HHHHTSEEEEE--SHHHHHHHHHHHHHT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        ThiF  14 ekLrdskvllvGaGglGsellknLalsG 41 
                   +r +kv +vG G  G+ +++n+   G
  EEA20469.1 373 YDVRGKKVIVVGTGNSGHDIAENFYENG 400
                 56899*****************998777 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.0     0.017        10       2      45 ..     211     253 ..     210     266 .. 0.84
   2 ?    5.2   0.0     0.021        13       2      33 ..     379     409 ..     378     418 .. 0.83

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.017
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHH CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelk 45 
                 +vl++Ga++  G+++a +l + G+++++vdr+e+   ++ k  +
  EEA20469.1 211 TVLIVGAGQA-GLNLAARLQSLGVSTLLVDRHERIGDNWRKRYR 253
                 79*****986.*********************987777766655 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.021
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESC CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrs 33 
                  v+v+G ++  G++ia++++++Ga+v++++r+
  EEA20469.1 379 KVIVVGTGN-SGHDIAENFYENGADVTMLQRR 409
                 677777664.4*****************9997 PP

>> ELFV_dehydrog  Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0       2.7   1.6e+03      33      57 ..     210     234 ..     199     239 .. 0.81
   2 ?    9.6   0.2    0.0012      0.71      21      66 ..     367     411 ..     358     422 .. 0.75

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 2.7
                    EEEEEE--SHHHHHHHHHHHHCT-E CS
  ELFV_dehydrog  33 krvaisGsGnvgsyaallltelgak 57 
                     +v i G G+ g + a  l++lg +
     EEA20469.1 210 PTVLIVGAGQAGLNLAARLQSLGVS 234
                    4899************999998865 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.0012
                    HHHHTTTS-STTEEEEEE--SHHHHHHHHHHHHCT-EEEEEEESSE CS
  ELFV_dehydrog  21 mlkklkldslegkrvaisGsGnvgsyaallltelgakvvavsDssG 66 
                      +  +  +++gk+v++ G Gn g+  a+ + e ga v+ ++    
     EEA20469.1 367 HRDASEY-DVRGKKVIVVGTGNSGHDIAENFYENGADVTMLQRRGT 411
                    4444344.59***********************9999876665544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (626 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       528  (0.0294495); expected 358.6 (0.02)
Passed bias filter:                      486  (0.0271069); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                        30  (0.00167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              30  [number of targets reported over threshold]
# CPU time: 0.71u 0.34s 00:00:01.05 Elapsed: 00:00:00.48
# Mc/sec: 3906.20
//
Query:       EEA20470.1  [L=267]
Description: cytosolic Cu/Zn superoxide dismutase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.5e-09   37.4   0.1    9.5e-09   35.6   0.1    1.9  1  Sod_Cu          Copper/zinc superoxide dismutase (SODC)
  ------ inclusion threshold ------
      0.051   12.4   0.1      0.059   12.2   0.1    1.1  1  Fungal_trans_2  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Sod_Cu  Copper/zinc superoxide dismutase (SODC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.6   0.1   1.1e-12   9.5e-09       5     113 ..      43     156 ..      40     165 .. 0.74

  Alignments for each domain:
  == domain 1  score: 35.6 bits;  conditional E-value: 1.1e-12
                 EEEEEEEEEEEECSTTSTCEEEEEEEECSS-.STEEEEEEEESSTTTTTT.TGGG-SB-STT-.CSSTT....TTTCS-TTEEEEEEESTTSEEEEEEE CS
      Sod_Cu   5 kgevsGtvtftqeeskesgsvevtvevkglp.pggkhgfHiHengdcsag.fksagghfnptgkkhgap....ndeerhaGDLgnievdadgtakleit 97 
                 +++v+G vt + ++  +  +++++v+++glp + g + +H+H  +   +g +++ag+h++p+++ ++ p    ++++  +GDL+  +  a gt+ +   
  EEA20470.1  43 STTVRGNVTASGAP--DGVGLVFRVNFTGLPaNIGPFPYHVHVSPVPANGnCSAAGEHLDPFNRGEQPPcdpsDPATCQVGDLSGKHGFATGTSFFAEY 139
                 4799******9877..456799*********633579********997777************9988665444444888*****555555555444333 PP

                 EESC.BCSTTT.BCTTE CS
      Sod_Cu  98 tdklvslkgen.silgr 113
                 td ++s ++++  ++g 
  EEA20470.1 140 TDLYLSTDPGSnAFIGD 156
                 57777777655346664 PP

>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.1   6.6e-06     0.059     203     287 ..     176     262 ..     131     266 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 6.6e-06
  Fungal_trans_2 203 isrLarekrsarkdseleplsileeaseleqrllswkprssdlepdldeterasslskdltelfrlaaliylyrlvlglpps...spe 287
                     ++rL    r  +++ +++++s + ++++  +r +s++p+s+ +++++++t++ s++ +++t++ r ++++   r+v+ +pp+   +p+
      EEA20470.1 176 VARLNVATRGGSSS-TTTHTSTRTSSTRVYTRTSSTRPTSTRTSSTRPTTHTSSTRPTTHTSSTRSTTRTTTARSVPTQPPTfttQPR 262
                     56666666666666.999***************************************************************9777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (267 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1088  (0.0606838); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        75  (0.00418317); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.31s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 1781.79
//
Query:       EEA20471.1  [L=513]
Description: MFS monosaccharide transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.6e-89  298.8  17.4      8e-89  298.6  17.4    1.0  1  Sugar_tr  Sugar (and other) transporter
    4.7e-32  111.3  40.5    1.3e-23   83.5  18.3    2.1  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.031   13.2   4.5      0.023   13.7   2.8    1.5  2  LMBR1     LMBR1-like membrane protein


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  298.6  17.4   1.3e-92     8e-89       8     452 .]      44     487 ..      37     487 .. 0.93

  Alignments for each domain:
  == domain 1  score: 298.6 bits;  conditional E-value: 1.3e-92
                 HHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGG CS
    Sugar_tr   8 ggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevli 106
                 + + +gYd  ++ ++ ++++++  +gl+++ ss+       gl+++i+++G++ +  +ag++ d +GR+ ++  ++ + +ig+++qa a    s +++i
  EEA20471.1  44 CIVFQGYDGSLMPSINAMPQYQQYYGLKSAGSST-------GLVFAIYNIGSLGSLPIAGPVNDLLGRRAGIFLGCCFIIIGTCVQAPAI---SRQMFI 132
                 55679*****************999999999855.......79***********************************************...89**** PP

                 GGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHHTT-HH CS
    Sugar_tr 107 vgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPrylvekgkee 205
                  gR+l+G+g G+++v +P+++sE+A++++Rg l +l+q+   +G ++a+++++g++  ++++ +ri+++lqlv + +++i+++f+PE+Pr+l+ +g+++
  EEA20471.1 133 GGRFLCGFGQGFVNVSAPLFVSELAHPRWRGPLSGLTQTNFFIGSIIASWVTYGTAFLDGEKAFRIPIWLQLVTTSIVAIGIWFAPETPRWLMAQGRRQ 231
                 *************************************************************************************************** PP

                 HHHHHHHHHHHC.HHHHHHHHHHHHHHHHHHH..........HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH...HHHHHH CS
    Sugar_tr 206 eakevlaklrge.edadrelaeekdsleaeqeee.....kaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsks...llvtii 295
                 ea++vla+l ge + ++ ++    +++e + +e+       +++ l+ ++  r+r++ ++++++f q++G++ + yy p+i +++g++++   ll +++
  EEA20471.1 232 EAERVLADLHGEgSTEHCCVRLQLAEMESQIRETgsdkrWWDYSGLFNTRPARRRMICVIGMAWFGQYSGNALVSYYFPVIVQQAGIDDPhmqLLLNAL 330
                 ********9999633333344344444444444345324555667777777***************************************999999999 PP

                 HHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS....CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHH CS
    Sugar_tr 296 vgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgivalllvaks.kaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiava 393
                   v+ +++ + +++l dr+GRR++ll G++gm++c++i+++++ l v+ s   as   i+fi+lf a+f+l++ p++ ++++E+  +++R+k++a+   
  EEA20471.1 331 NPVISWFIAILGAMLLDRVGRRPFLLAGVLGMSLCLAIVTGCTKLSVDYSnRDASHTGIFFIYLFSAIFSLCIVPLIPFYIAETLATETRAKGTAVGQL 429
                 99**************************************99999999998999********************************************* PP

                 HHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 394 vnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                     a++l ++++ ++ ++ig +y++lvf +  ++ +++++ff++etk rtlee++e+f
  EEA20471.1 430 FGSAASILGQYTTATAIGSIG-YYYYLVFIFWDLVEFVIIYFFFVETKERTLEEMTEIF 487
                 *********************.**********************************987 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.5  18.3   2.2e-27   1.3e-23      16     289 ..      58     367 ..      38     368 .. 0.78
   2 !   41.9  14.2   9.9e-15   5.9e-11       6     178 ..     296     478 ..     287     504 .. 0.77

  Alignments for each domain:
  == domain 1  score: 83.5 bits;  conditional E-value: 2.2e-27
       MFS_1  16 gpalplalaedlg..ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.sslwlllvlrvlqGlgagalfpagaalia 111
                 + a+p  +++ +g  +++s+ gl++++y +g++ + +++G++ d +Grr  ++lg  + ++g ++   + +s  +++ +r+l+G+g+g+++ ++  +++
  EEA20471.1  58 INAMP-QYQQYYGlkSAGSSTGLVFAIYNIGSLGSLPIAGPVNDLLGRRAGIFLGCCFIIIG-TCVQAPaISRQMFIGGRFLCGFGQGFVNVSAPLFVS 154
                 33444.55666665599999******************************777777777777.44442126666************************* PP

       MFS_1 112 dwfpkeergraigllsagfslGailgpllggllasslg...Wravfyilaivsllafvlfllllpeepperkrkspkeee................... 188
                 ++++++ rg   gl ++ f +G+i++  +    a + g   +r + ++  + + ++++ ++++ pe+p+    +  ++e                    
  EEA20471.1 155 ELAHPRWRGPLSGLTQTNFFIGSIIASWVTYGTAFLDGekaFRIPIWLQLVTTSIVAI-GIWFAPETPRWLMAQGRRQEAervladlhgegstehccvr 252
                 ****************************9998874444788***************99.6699999999999999988878999999999999988888 PP

       MFS_1 189 ...........kgtgpaplvpawkallkdpvlw.illialllfffgfsg....lltllplylqevlgls....glllaglllallalvgailallagrl 267
                            +    + + + ++ l++ ++    +++++ +++fg ++    +++++p++ +++ g++        ++ l al  +++ ++a+l++ l
  EEA20471.1 253 lqlaemesqirETGSDKRWWD-YSGLFNTRPARrRMICVIGMAWFGQYSgnalVSYYFPVI-VQQAGIDdphmQ---LL-LNALNPVISWFIAILGAML 345
                 877777766664444444444.6777777766444555555555555557888*******7.*******95443...44.5556666666668899999 PP

       MFS_1 268 sdrlgrrrrlllallllllaal 289
                 +dr+grr++ll ++l+++l+++
  EEA20471.1 346 LDRVGRRPFLLAGVLGMSLCLA 367
                 9******************987 PP

  == domain 2  score: 41.9 bits;  conditional E-value: 9.9e-15
       MFS_1   6 flsalarsilgpalplalaedlgispseigl.lltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll....fa.......sslwlllvlr 92 
                 f  + + ++++  +p  + ++ gi+   ++l l +l  + +++ +++++ l dr+Grr++ll+g+l+++l+l++ +    ++       +s++ +++  
  EEA20471.1 296 FGQYSGNALVSYYFP-VIVQQAGIDDPHMQLlLNALNPVISWFIAILGAMLLDRVGRRPFLLAGVLGMSLCLAIVTgctkLSvdysnrdASHTGIFFIY 393
                 455666677888899.89999999999999956667999********************************4444455443256667776677788888 PP

       MFS_1  93 vlqGlgagalfpagaaliadwfpkeergraigllsagfslGailg.pllggllasslgWravfyilaivsllafvlfllllpeeppe 178
                 +++++++ +++p++  +ia+  + e r++++++ +++ s+++ilg +  + ++  s+g+ + ++++ +  l+ fv+++++++e++ +
  EEA20471.1 394 LFSAIFSLCIVPLIPFYIAETLATETRAKGTAVGQLFGSAASILGqYTTATAIG-SIGY-YYYLVFIFWDLVEFVIIYFFFVETKER 478
                 99999999*************************************555555555.7774.456666666666666666777655544 PP

>> LMBR1  LMBR1-like membrane protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0      0.53   3.2e+03     129     149 ..      31      54 ..      11      87 .. 0.50
   2 ?   13.7   2.8   3.8e-06     0.023       7     115 ..     362     480 ..     356     489 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 0.53
       LMBR1 129 iyllllvivlglliyvliil...q 149
                 +y l++v+ lg l +v+       
  EEA20471.1  31 MYRLYAVLALGYLCIVFQGYdgsL 54 
                 444555555555555554444443 PP

  == domain 2  score: 13.7 bits;  conditional E-value: 3.8e-06
       LMBR1   7 lllflllfllallllrrykrkkdqeavvkllvllalalsflivlllPlDiastiyrq...............nealypcsyylqwlseslikvlWrivY 90 
                 + l+l++      l + y++++ ++  + ++ l++  +s++iv l+P+ ia t  ++               +       +y+++   + i  ++ +v+
  EEA20471.1 362 MSLCLAIVTGCTKLSVDYSNRDASHTGIFFIYLFSAIFSLCIVPLIPFYIAETLATEtrakgtavgqlfgsaA---SILGQYTTATAIGSIGYYYYLVF 457
                 445555556666699**************************************9999*******988887653...34688999999999********* PP

       LMBR1  91 wlsnlllwiilPfaqfYvesggftg 115
                 ++  l  ++i+   +f+ve +++t 
  EEA20471.1 458 IFWDLVEFVII--YFFFVETKERTL 480
                 **********6..778888888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (513 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       691  (0.0385409); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.59u 0.31s 00:00:00.89 Elapsed: 00:00:00.48
# Mc/sec: 3239.26
//
Query:       EEA20472.1  [L=417]
Description: ethanolamine kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.2e-47  160.2   0.0    8.6e-46  156.2   0.0    2.0  2  Choline_kinase  Choline/ethanolamine kinase
    4.1e-09   36.7   0.1    1.4e-08   35.0   0.0    1.9  2  APH             Phosphotransferase enzyme family


Domain annotation for each model (and alignments):
>> Choline_kinase  Choline/ethanolamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  156.2   0.0   9.6e-50   8.6e-46       2     211 ..      70     313 ..      69     315 .. 0.91
   2 ?    1.8   0.0     0.017   1.5e+02     165     177 ..     371     383 ..     367     387 .. 0.83

  Alignments for each domain:
  == domain 1  score: 156.2 bits;  conditional E-value: 9.6e-50
                     SSEEEEEEE-TTCTTCCHHHHHHHHHHHHHHTTSSS-EEEEETTEEEEE--TCEE--TTGGGCHHHHHHHHHHHHHHTTCHH............. CS
  Choline_kinase   2 kkkvllRiygkkteelidretElvvfallserglgpklygifenGrieefiesrtlstedlrepeiskkiAkklaelHslel............. 83 
                     ++ vl+R yg++te lidre+E+  + ll+++gl+p l+++f+nG ++ fi ++ +s+ dl +p++++ +A++l+++H++ +             
      EEA20472.1  70 NEAVLMRAYGNHTEILIDRERETRSHSLLAQHGLAPPLLARFKNGLLYCFIRGHVTSPSDLIQPSVWRGVARRLGQWHAVLPitssadddqtsss 164
                     689*****************************************************************************99************* PP

                     .......................TTSSSS-HHHHHHHHHHHCCS.TT..ECHHGGCCHCCCTHHHHHHHHHTHHHHHHCHGG-EEEE-S--SGGG CS
  Choline_kinase  84 ......................eseskespslwktmqkwllnkeaqtkakkekkkkqlklinledlekelekleklleelespvvfcHnDlqegN 156
                                            ++++  p+lw+ mqkw+l   +qt+     ++ + ++   ++le++l++l       es ++f+H+Dl++ N
      EEA20472.1 165 ssqddydvnkpdgtskasaitpIRPRQAGPNLWTVMQKWILALPVQTE-----EQRSRQKTLQTELERTLNELDDGSGIGESGLIFAHCDLLSAN 254
                     *********************98899*************332222222.....22223334455677777888888888999************* PP

                     EEE.............-CTTEEEE--GTT-EEEEHHHHHHHHHHHTTEEHHHCSTSHEE-GGGS--H CS
  Choline_kinase 157 ill............nkeekklvlIDFEYagynyrgfDlanhfiEwagdyeeeeaffkldyskypsr 211
                     +++            +++ +++ +ID+EYa++++++fD+anhf+Ew g        +++dy+ +p+r
      EEA20472.1 255 VIVipheetngvvsgDSDSQDVHFIDYEYATPSPAAFDIANHFAEWGG--------YDCDYNMLPTR 313
                     ************************************************........89999988886 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.017
                     EEEE--GTT-EEE CS
  Choline_kinase 165 klvlIDFEYagyn 177
                     ++  IDF Ya+y 
      EEA20472.1 371 TISQIDFDYASYA 383
                     6888*******97 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.0   0.0   1.5e-12   1.4e-08      37     213 ..      88     301 ..      45     334 .. 0.72
   2 ?   -1.6   0.0      0.24   2.1e+03     191     215 ..     375     396 ..     365     415 .. 0.67

  Alignments for each domain:
  == domain 1  score: 35.0 bits;  conditional E-value: 1.5e-12
                 HHHHHHHHHHHHHTT-B--B-CTTBS-EEETTEEEEEEE----EE-SSHHHHHHHHHHHHHHHHHHCCHHCH.-STTTB-................... CS
         APH  37 irrevallrlLakagvpvPevlagdtddeeigllfalieyvpgrsllrklsaaqlpellealgeflaalhqvdpaalpla................... 116
                  +re ++  lLa++g+ +P +la    +  +g   +l+ ++ g++ ++  s+ ++p +++ +++ l++ h+v p ++  +                   
  EEA20472.1  88 RERETRSHSLLAQHGL-APPLLA----RFKNG---LLYCFIRGHVTSP--SDLIQPSVWRGVARRLGQWHAVLPITSSADddqtsssssqddydvnkpd 176
                 4677788899999999.999999....33444...5666777799999..899*******************644444445666666666666666666 PP

                 ..........SHHCHTCCHHHHHHCHHHCCCGCCTCC...HHHHHHHHHHHHHHHH--S....SS-EEEE-SS-SGGGEEEC...............TT CS
         APH 117 ..........dflaqdlellrqlesatarllaselld...lleeleeqvlaalaallpg....elptvllHgDlhpgNllvd.............pddg 185
                            +++q   +l+ +++     l+ ++++   ++  l  ++ ++l +l +g    e+   + H+Dl + N++v              +   
  EEA20472.1 177 gtskasaitpIRPRQAGPNLWTVMQKWILALPVQTEEqrsRQKTLQTELERTLNELDDGsgigESGLIFAHCDLLSANVIVIpheetngvvsgdsD--S 273
                 77777777764444444444444444333333333332323333333344444444444***9**********************99999999544..4 PP

                 EEEEE---TT-EEEECCHHHHCCHHHCS CS
         APH 186 rvtGviDfedaglgpplyDlavllrswt 213
                 + + +iD e+a+++p+++D+a + + w+
  EEA20472.1 274 QDVHFIDYEYATPSPAAFDIANHFAEWG 301
                 4455*****************9995565 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.24
                 ---TT-EEEECCHHHHCCHHHCSCH CS
         APH 191 iDfedaglgpplyDlavllrswtse 215
                 iDf++a+++   + l+  + +w++e
  EEA20472.1 375 IDFDYASYA--EVRLGEYW-AWRRE 396
                 788888877..33334444.44444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (417 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       544  (0.0303419); expected 358.6 (0.02)
Passed bias filter:                      473  (0.0263818); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 2695.27
//
Query:       EEA20473.1  [L=417]
Description: ethanolamine kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.2e-47  160.2   0.0    8.6e-46  156.2   0.0    2.0  2  Choline_kinase  Choline/ethanolamine kinase
    4.1e-09   36.7   0.1    1.4e-08   35.0   0.0    1.9  2  APH             Phosphotransferase enzyme family


Domain annotation for each model (and alignments):
>> Choline_kinase  Choline/ethanolamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  156.2   0.0   9.6e-50   8.6e-46       2     211 ..      70     313 ..      69     315 .. 0.91
   2 ?    1.8   0.0     0.017   1.5e+02     165     177 ..     371     383 ..     367     387 .. 0.83

  Alignments for each domain:
  == domain 1  score: 156.2 bits;  conditional E-value: 9.6e-50
                     SSEEEEEEE-TTCTTCCHHHHHHHHHHHHHHTTSSS-EEEEETTEEEEE--TCEE--TTGGGCHHHHHHHHHHHHHHTTCHH............. CS
  Choline_kinase   2 kkkvllRiygkkteelidretElvvfallserglgpklygifenGrieefiesrtlstedlrepeiskkiAkklaelHslel............. 83 
                     ++ vl+R yg++te lidre+E+  + ll+++gl+p l+++f+nG ++ fi ++ +s+ dl +p++++ +A++l+++H++ +             
      EEA20473.1  70 NEAVLMRAYGNHTEILIDRERETRSHSLLAQHGLAPPLLARFKNGLLYCFIRGHVTSPSDLIQPSVWRGVARRLGQWHAVLPitssadddqtsss 164
                     689*****************************************************************************99************* PP

                     .......................TTSSSS-HHHHHHHHHHHCCS.TT..ECHHGGCCHCCCTHHHHHHHHHTHHHHHHCHGG-EEEE-S--SGGG CS
  Choline_kinase  84 ......................eseskespslwktmqkwllnkeaqtkakkekkkkqlklinledlekelekleklleelespvvfcHnDlqegN 156
                                            ++++  p+lw+ mqkw+l   +qt+     ++ + ++   ++le++l++l       es ++f+H+Dl++ N
      EEA20473.1 165 ssqddydvnkpdgtskasaitpIRPRQAGPNLWTVMQKWILALPVQTE-----EQRSRQKTLQTELERTLNELDDGSGIGESGLIFAHCDLLSAN 254
                     *********************98899*************332222222.....22223334455677777888888888999************* PP

                     EEE.............-CTTEEEE--GTT-EEEEHHHHHHHHHHHTTEEHHHCSTSHEE-GGGS--H CS
  Choline_kinase 157 ill............nkeekklvlIDFEYagynyrgfDlanhfiEwagdyeeeeaffkldyskypsr 211
                     +++            +++ +++ +ID+EYa++++++fD+anhf+Ew g        +++dy+ +p+r
      EEA20473.1 255 VIVipheetngvvsgDSDSQDVHFIDYEYATPSPAAFDIANHFAEWGG--------YDCDYNMLPTR 313
                     ************************************************........89999988886 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.017
                     EEEE--GTT-EEE CS
  Choline_kinase 165 klvlIDFEYagyn 177
                     ++  IDF Ya+y 
      EEA20473.1 371 TISQIDFDYASYA 383
                     6888*******97 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.0   0.0   1.5e-12   1.4e-08      37     213 ..      88     301 ..      45     334 .. 0.72
   2 ?   -1.6   0.0      0.24   2.1e+03     191     215 ..     375     396 ..     365     415 .. 0.67

  Alignments for each domain:
  == domain 1  score: 35.0 bits;  conditional E-value: 1.5e-12
                 HHHHHHHHHHHHHTT-B--B-CTTBS-EEETTEEEEEEE----EE-SSHHHHHHHHHHHHHHHHHHCCHHCH.-STTTB-................... CS
         APH  37 irrevallrlLakagvpvPevlagdtddeeigllfalieyvpgrsllrklsaaqlpellealgeflaalhqvdpaalpla................... 116
                  +re ++  lLa++g+ +P +la    +  +g   +l+ ++ g++ ++  s+ ++p +++ +++ l++ h+v p ++  +                   
  EEA20473.1  88 RERETRSHSLLAQHGL-APPLLA----RFKNG---LLYCFIRGHVTSP--SDLIQPSVWRGVARRLGQWHAVLPITSSADddqtsssssqddydvnkpd 176
                 4677788899999999.999999....33444...5666777799999..899*******************644444445666666666666666666 PP

                 ..........SHHCHTCCHHHHHHCHHHCCCGCCTCC...HHHHHHHHHHHHHHHH--S....SS-EEEE-SS-SGGGEEEC...............TT CS
         APH 117 ..........dflaqdlellrqlesatarllaselld...lleeleeqvlaalaallpg....elptvllHgDlhpgNllvd.............pddg 185
                            +++q   +l+ +++     l+ ++++   ++  l  ++ ++l +l +g    e+   + H+Dl + N++v              +   
  EEA20473.1 177 gtskasaitpIRPRQAGPNLWTVMQKWILALPVQTEEqrsRQKTLQTELERTLNELDDGsgigESGLIFAHCDLLSANVIVIpheetngvvsgdsD--S 273
                 77777777764444444444444444333333333332323333333344444444444***9**********************99999999544..4 PP

                 EEEEE---TT-EEEECCHHHHCCHHHCS CS
         APH 186 rvtGviDfedaglgpplyDlavllrswt 213
                 + + +iD e+a+++p+++D+a + + w+
  EEA20473.1 274 QDVHFIDYEYATPSPAAFDIANHFAEWG 301
                 4455*****************9995565 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.24
                 ---TT-EEEECCHHHHCCHHHCSCH CS
         APH 191 iDfedaglgpplyDlavllrswtse 215
                 iDf++a+++   + l+  + +w++e
  EEA20473.1 375 IDFDYASYA--EVRLGEYW-AWRRE 396
                 788888877..33334444.44444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (417 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       544  (0.0303419); expected 358.6 (0.02)
Passed bias filter:                      473  (0.0263818); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.50
# Mc/sec: 2485.89
//
Query:       EEA20474.1  [L=183]
Description: ADP-ribosylation factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    4.4e-79  264.0   0.5    5.2e-79  263.7   0.5    1.0  1  Arf        ADP-ribosylation factor family
      3e-14   53.3   0.0    4.3e-14   52.8   0.0    1.2  1  Roc        Ras of Complex, Roc, domain of DAPkinase
    3.9e-14   52.5   0.0    4.9e-14   52.2   0.0    1.1  1  SRPRB      Signal recognition particle receptor beta subunit
    2.2e-13   50.2   0.0    2.4e-13   50.0   0.0    1.0  1  Ras        Ras family
    2.2e-13   50.1   1.3    1.9e-09   37.1   0.5    2.3  2  G-alpha    G-protein alpha subunit
    2.5e-10   40.1   0.0      3e-10   39.9   0.0    1.1  1  Gtr1_RagA  Gtr1/RagA G protein conserved region
    4.2e-06   26.8   0.0    6.4e-06   26.2   0.0    1.3  1  MMR_HSR1   50S ribosome-binding GTPase
  ------ inclusion threshold ------
       0.01   15.1   0.5      0.028   13.7   0.1    1.7  2  6PF2K      6-phosphofructo-2-kinase


Domain annotation for each model (and alignments):
>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  263.7   0.5   2.3e-82   5.2e-79       2     174 ..       6     176 ..       5     177 .. 0.98

  Alignments for each domain:
  == domain 1  score: 263.7 bits;  conditional E-value: 2.3e-82
                 HHHHHGGTT.TTEEEEEEEESTTSSHHHHHHHHHHSSCEECSSSSSEEEEEEEETTEEEEEEEE-SSGGGGGGGGGGCTTESEEEEEEETT-CTTHHHH CS
         Arf   2 lsilaklklkkkelrilllGLDnaGKtTilkklkleelvttvPTigfnveeleiknlkftvwDvGGqeklRplWknYfektdavifvvDsadreRleea 100
                 +++l++l++ kke+ril++GLD+aGKtTil+klkl+e+vtt+PTigfnve++e+kn++ftvwDvGGq+k+RplW++Yf++t+++ifvvDs+dr+R+ ea
  EEA20474.1   6 SKLLDRLWG-KKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNIQFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRDRIVEA 103
                 678889999.9**************************************************************************************** PP

                 HHHHHHHCTSGCCTTSEEEEEEE-TTSTTSS-HHHHHHHTTGGGSSSSSSEEEEEEBTTTTBTHHHHHHHHHHH CS
         Arf 101 keeLkalleeeelkevallvlaNKqDlpealseeelrellgleelkgkrkleiqkcsavkgeglkeglewlses 174
                 +eeL+++l+e+el+++ llv+aNKqDlp+a+s +e++++lgl++l+ +r ++iq+++a++g+gl+eglewl+e+
  EEA20474.1 104 REELQRMLNEDELRDALLLVFANKQDLPNAMSIAEITQQLGLQSLT-RRAWYIQSTCATTGDGLYEGLEWLAET 176
                 **********************************************.************************986 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.8   0.0   1.9e-17   4.3e-14       1     119 [.      19     129 ..      19     130 .. 0.78

  Alignments for each domain:
  == domain 1  score: 52.8 bits;  conditional E-value: 1.9e-17
                 EEEEESSTTSSHHHHHHCHCT-CCC-EEETTTTEEEEEEECGGSGGCTTBTTTTCEEEEEEEE-SGGCTTTT-HHHHCTSCEEEEEEEGHHHHCHHHHH CS
         Roc   1 KvvlvGdsgvGKtsllkrfvedkfsekekstigvdfltkevtkikgvendkkvkkvklniWDtaGqerfrslhplylreaalailvydsrssenlkeWl 99 
                 ++++vG  ++GKt++l ++  +++  ++ +tig ++ t e+            k++++ +WD++Gq+++r l ++y+++ + +i+v+ds++ +++ e  
  EEA20474.1  19 RILMVGLDAAGKTTILYKLKLGEIV-TTIPTIGFNVETVEY------------KNIQFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRDRIVEAR 104
                 699*******************996.568*****9966443............5799*******************************88877665555 PP

                 HHHHHHCSSS....-.EEEEEE-TT CS
         Roc 100 kelkkvagks....p.vilvgnkiD 119
                 +el+++ +++      +++ +nk D
  EEA20474.1 105 EELQRMLNEDelrdAlLLVFANKQD 129
                 5555554433111131456679988 PP

>> SRPRB  Signal recognition particle receptor beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.2   0.0   2.2e-17   4.9e-14       2     137 ..      16     143 ..      15     154 .. 0.88

  Alignments for each domain:
  == domain 1  score: 52.2 bits;  conditional E-value: 2.2e-17
                 ---EEEEE-STTSSHHHHHHHHHHSS---B---S.S-EEETTG...GGTT-SEEEETT-GCCSHHHHHHHHHHGGEEEEEEEEETTS-HHHHHHHHHHH CS
       SRPRB   2 skpavllvGlsdsGKTslftrLttdsvkktvtSq.essaalkvksekgskltliDfPGheklrqklleklkaksslkglvfvvDStidpkevkevAEll 99 
                 ++ ++l+vGl  +GKT+++ +L  +++ +t   +  +  + ++   k+ ++t+ D+ G++k+r     +  + ++ +g++fvvDS  d  ++ e  E l
  EEA20474.1  16 KEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIgFNVETVEY---KNIQFTVWDVGGQDKIRPL-WRH--YFQNTQGIIFVVDSN-DRDRIVEAREEL 107
                 5678******************************888999999...*****************75.555..57889********98.666788999999 PP

                 HHHHHHHHHHTT---EEEEEE-TTSTT---HHHHHHHH CS
       SRPRB 100 yeilliteklkdavdiliACnKqelflakspklikdaL 137
                   +l + e l+da+ +l+  nKq+l  a s   i ++L
  EEA20474.1 108 QRMLNEDE-LRDAL-LLVFANKQDLPNAMSIAEITQQL 143
                 ***99999.66766.67777***************998 PP

>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.0   0.0   1.1e-16   2.4e-13       2     159 ..      20     176 ..      19     179 .. 0.79

  Alignments for each domain:
  == domain 1  score: 50.0 bits;  conditional E-value: 1.1e-16
                 EEEEESTTSSHHHHHHHHHHSSCSSSCTTTSSEEEEEEEEEETTEEEEEEEEEETTSGGGHHHHHHHHTTESEEEEEEETTBHHHHHTHHHHHHHHHHH CS
         Ras   2 lvlvGdsavGKtslllrfvkdkFkeeyesTigvdfytkeievdgkevkleiwDTAGqeefkslrelyyrdaegillvyditsresfenvkkwveeikrv 100
                 +++vG  a GKt++l++   ++  ++ ++Tig++    +  v+ k++++++wD  Gq++ + l + y+++++gi+ v d ++r+   ++++ ++ + + 
  EEA20474.1  20 ILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVE--T--VEYKNIQFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRDRIVEAREELQRMLNE 113
                 899*******************9976.9***87654..4..456799************************************9999999666666655 PP

                 ST.TTSEEEEEEETTTGGG...G-SS-HHHHHHHHHHHTSEEEEEBTTTTCTHHHHHHHHHHH CS
         Ras 101 ae.envpivLvGnKvDlee...kravsteegeelakelglkfletSAktnenveeafeellre 159
                  e ++  +++ +nK Dl +     +++++ g +   +       t A t  ++ e +e l+++
  EEA20474.1 114 DElRDALLLVFANKQDLPNamsIAEITQQLGLQSLTRRAWYIQSTCATTGDGLYEGLEWLAET 176
                 55688999999*******944444555566655555555555567777777777777777666 PP

>> G-alpha  G-protein alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.0   3.7e-05     0.084      21      45 ..      15      39 ..       6      44 .. 0.88
   2 !   37.1   0.5   8.6e-13   1.9e-09     185     280 ..      45     129 ..      35     133 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 3.7e-05
                ..EEEEEEEESTTSSHHHHHHHHHH CS
     G-alpha 21 krevkllllGqseSGKsTilkqlkl 45
                k+e+++l++G +  GK+Til +lkl
  EEA20474.1 15 KKEMRILMVGLDAAGKTTILYKLKL 39
                569*****************99985 PP

  == domain 2  score: 37.1 bits;  conditional E-value: 8.6e-13
                 -----SEEEEEEECT-TEEEEEEEE-SSHHHHHGTCCCTTTECEEEEEEEGGGTT-B-SS-TTSBHHHHHHHHHHCCCC-GGGTTSEEEEEEE-HH CS
     G-alpha 185 rlktvGisetkfevdsklefrivdvgGqrserkkWvpffddvdaiiFlvslsefdqvlyedekvnrleeslklFkeicnnkllkntpiiLflnKlD 280
                  ++t+G++  ++e++ +++f+++dvgGq + r+ W ++f++++ iiF+v   + d          r+ e+ +  + ++n+ +l+++ +++f nK D
  EEA20474.1  45 TIPTIGFNVETVEYK-NIQFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRD----------RIVEAREELQRMLNEDELRDALLLVFANKQD 129
                 47899*999999999.********************************9955554..........5555555555556666666666666666665 PP

>> Gtr1_RagA  Gtr1/RagA G protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.9   0.0   1.3e-13     3e-10       1     135 [.      19     142 ..      19     162 .. 0.86

  Alignments for each domain:
  == domain 1  score: 39.9 bits;  conditional E-value: 1.3e-13
   Gtr1_RagA   1 kvLLmGksgsGKtsmrsiiFdnylardtlrlgatidveksevrflgnltlnlwDcgGqeafveeylssqkeeifrnvgvliyVfDvesre.leedletl 98 
                 ++L++G   +GKt++      ++   ++++   ti  + ++v  ++n+++ +wD+gGq+++          + f+n + +i+V+D+++r+ + e+ e+l
  EEA20474.1  19 RILMVGLDAAGKTTI----LYKLKLGEIVTTIPTIGFNVETV-EYKNIQFTVWDVGGQDKIRPLW-----RHYFQNTQGIIFVVDSNDRDrIVEAREEL 107
                 589**********85....5678889999999**********.599*************987664.....899**************997799999999 PP

   Gtr1_RagA  99 keilealrqyspeakvfvlihKmDliqedereeifee 135
                 +++l++  +  ++a + v+ +K Dl + +  +ei ++
  EEA20474.1 108 QRMLNE--DELRDALLLVFANKQDLPNAMSIAEITQQ 142
                 999985..667999999*******9888777777665 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.2   0.0   2.9e-09   6.4e-06       1     110 [.      19     122 ..      19     127 .. 0.72

  Alignments for each domain:
  == domain 1  score: 26.2 bits;  conditional E-value: 2.9e-09
                 EEEEEESTTSSHHHHHHHH.HTSTEEESSSTTSSSSEEEEEEEETTEEEEEEECGGCSSHHHHHH.HHHHHHHHHHCTSEEEEEEETT.TTCSHHHHHH CS
    MMR_HSR1   1 evaivGrpNvGKStLinal.tgekaivsdkpgtTrdinegrvklkgkeielvDtpGliegaseek.glgkaflaleeadlillvvdas.eeklkpldee 96 
                 +++ vG   +GK+t++ +l +g   iv+ +p  T+  n ++v++k+ +++++D+ G  +    +   l +++ +  +++ i++vvd++ ++ + + +ee
  EEA20474.1  19 RILMVGLDAAGKTTILYKLkLG--EIVTTIP--TIGFNVETVEYKNIQFTVWDVGG-QD----KIrPLWRHYFQ--NTQGIIFVVDSNdRDRIVEAREE 106
                 5889***************444..5788787..7777777777779**********.43....22357777775..578*******7764467778899 PP

                 HHHHHHH..TTSEEEE CS
    MMR_HSR1  97 leellee..akkplil 110
                 l+++l+e   ++ l+l
  EEA20474.1 107 LQRMLNEdeLRDALLL 122
                 9999877542222333 PP

>> 6PF2K  6-phosphofructo-2-kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.1   1.2e-05     0.028      12      51 ..      16      55 ..      10      68 .. 0.83
   2 ?   -0.7   0.0      0.33   7.4e+02      90     135 ..      80     127 ..      71     141 .. 0.75

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.2e-05
                S-EEEEEESSTTSSHHHHHHHHHHHHHHTT--EEEEEHHH CS
       6PF2K 12 sklvivlvGLpargKtyiskkltrylkwlgvrtkvFnvgk 51
                +++ i++vGL a gKt+i  kl      ++++t  Fnv  
  EEA20474.1 16 KEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVET 55
                56789***************99877778888888888865 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.33
                 HHHHTS--SEEEEES---SH..HHHHHHHHHHHHTT-EEEEEEEE--H CS
       6PF2K  90 aylneeegqvaifDAtNttr..erRklilefveennlkvlflesicsd 135
                 +y+++ +g + + D     r  e R+ + ++++e +l+  +l ++++ 
  EEA20474.1  80 HYFQNTQGIIFVVDSNDRDRivEAREELQRMLNEDELRDALLLVFANK 127
                 789999999999998776664467888888888877776666555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (183 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       655  (0.036533); expected 358.6 (0.02)
Passed bias filter:                      562  (0.0313459); expected 358.6 (0.02)
Passed Vit filter:                        73  (0.00407162); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1249.39
//
Query:       EEA20475.1  [L=183]
Description: ADP-ribosylation factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    4.4e-79  264.0   0.5    5.2e-79  263.7   0.5    1.0  1  Arf        ADP-ribosylation factor family
      3e-14   53.3   0.0    4.3e-14   52.8   0.0    1.2  1  Roc        Ras of Complex, Roc, domain of DAPkinase
    3.9e-14   52.5   0.0    4.9e-14   52.2   0.0    1.1  1  SRPRB      Signal recognition particle receptor beta subunit
    2.2e-13   50.2   0.0    2.4e-13   50.0   0.0    1.0  1  Ras        Ras family
    2.2e-13   50.1   1.3    1.9e-09   37.1   0.5    2.3  2  G-alpha    G-protein alpha subunit
    2.5e-10   40.1   0.0      3e-10   39.9   0.0    1.1  1  Gtr1_RagA  Gtr1/RagA G protein conserved region
    4.2e-06   26.8   0.0    6.4e-06   26.2   0.0    1.3  1  MMR_HSR1   50S ribosome-binding GTPase
  ------ inclusion threshold ------
       0.01   15.1   0.5      0.028   13.7   0.1    1.7  2  6PF2K      6-phosphofructo-2-kinase


Domain annotation for each model (and alignments):
>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  263.7   0.5   2.3e-82   5.2e-79       2     174 ..       6     176 ..       5     177 .. 0.98

  Alignments for each domain:
  == domain 1  score: 263.7 bits;  conditional E-value: 2.3e-82
                 HHHHHGGTT.TTEEEEEEEESTTSSHHHHHHHHHHSSCEECSSSSSEEEEEEEETTEEEEEEEE-SSGGGGGGGGGGCTTESEEEEEEETT-CTTHHHH CS
         Arf   2 lsilaklklkkkelrilllGLDnaGKtTilkklkleelvttvPTigfnveeleiknlkftvwDvGGqeklRplWknYfektdavifvvDsadreRleea 100
                 +++l++l++ kke+ril++GLD+aGKtTil+klkl+e+vtt+PTigfnve++e+kn++ftvwDvGGq+k+RplW++Yf++t+++ifvvDs+dr+R+ ea
  EEA20475.1   6 SKLLDRLWG-KKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNIQFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRDRIVEA 103
                 678889999.9**************************************************************************************** PP

                 HHHHHHHCTSGCCTTSEEEEEEE-TTSTTSS-HHHHHHHTTGGGSSSSSSEEEEEEBTTTTBTHHHHHHHHHHH CS
         Arf 101 keeLkalleeeelkevallvlaNKqDlpealseeelrellgleelkgkrkleiqkcsavkgeglkeglewlses 174
                 +eeL+++l+e+el+++ llv+aNKqDlp+a+s +e++++lgl++l+ +r ++iq+++a++g+gl+eglewl+e+
  EEA20475.1 104 REELQRMLNEDELRDALLLVFANKQDLPNAMSIAEITQQLGLQSLT-RRAWYIQSTCATTGDGLYEGLEWLAET 176
                 **********************************************.************************986 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.8   0.0   1.9e-17   4.3e-14       1     119 [.      19     129 ..      19     130 .. 0.78

  Alignments for each domain:
  == domain 1  score: 52.8 bits;  conditional E-value: 1.9e-17
                 EEEEESSTTSSHHHHHHCHCT-CCC-EEETTTTEEEEEEECGGSGGCTTBTTTTCEEEEEEEE-SGGCTTTT-HHHHCTSCEEEEEEEGHHHHCHHHHH CS
         Roc   1 KvvlvGdsgvGKtsllkrfvedkfsekekstigvdfltkevtkikgvendkkvkkvklniWDtaGqerfrslhplylreaalailvydsrssenlkeWl 99 
                 ++++vG  ++GKt++l ++  +++  ++ +tig ++ t e+            k++++ +WD++Gq+++r l ++y+++ + +i+v+ds++ +++ e  
  EEA20475.1  19 RILMVGLDAAGKTTILYKLKLGEIV-TTIPTIGFNVETVEY------------KNIQFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRDRIVEAR 104
                 699*******************996.568*****9966443............5799*******************************88877665555 PP

                 HHHHHHCSSS....-.EEEEEE-TT CS
         Roc 100 kelkkvagks....p.vilvgnkiD 119
                 +el+++ +++      +++ +nk D
  EEA20475.1 105 EELQRMLNEDelrdAlLLVFANKQD 129
                 5555554433111131456679988 PP

>> SRPRB  Signal recognition particle receptor beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.2   0.0   2.2e-17   4.9e-14       2     137 ..      16     143 ..      15     154 .. 0.88

  Alignments for each domain:
  == domain 1  score: 52.2 bits;  conditional E-value: 2.2e-17
                 ---EEEEE-STTSSHHHHHHHHHHSS---B---S.S-EEETTG...GGTT-SEEEETT-GCCSHHHHHHHHHHGGEEEEEEEEETTS-HHHHHHHHHHH CS
       SRPRB   2 skpavllvGlsdsGKTslftrLttdsvkktvtSq.essaalkvksekgskltliDfPGheklrqklleklkaksslkglvfvvDStidpkevkevAEll 99 
                 ++ ++l+vGl  +GKT+++ +L  +++ +t   +  +  + ++   k+ ++t+ D+ G++k+r     +  + ++ +g++fvvDS  d  ++ e  E l
  EEA20475.1  16 KEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIgFNVETVEY---KNIQFTVWDVGGQDKIRPL-WRH--YFQNTQGIIFVVDSN-DRDRIVEAREEL 107
                 5678******************************888999999...*****************75.555..57889********98.666788999999 PP

                 HHHHHHHHHHTT---EEEEEE-TTSTT---HHHHHHHH CS
       SRPRB 100 yeilliteklkdavdiliACnKqelflakspklikdaL 137
                   +l + e l+da+ +l+  nKq+l  a s   i ++L
  EEA20475.1 108 QRMLNEDE-LRDAL-LLVFANKQDLPNAMSIAEITQQL 143
                 ***99999.66766.67777***************998 PP

>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.0   0.0   1.1e-16   2.4e-13       2     159 ..      20     176 ..      19     179 .. 0.79

  Alignments for each domain:
  == domain 1  score: 50.0 bits;  conditional E-value: 1.1e-16
                 EEEEESTTSSHHHHHHHHHHSSCSSSCTTTSSEEEEEEEEEETTEEEEEEEEEETTSGGGHHHHHHHHTTESEEEEEEETTBHHHHHTHHHHHHHHHHH CS
         Ras   2 lvlvGdsavGKtslllrfvkdkFkeeyesTigvdfytkeievdgkevkleiwDTAGqeefkslrelyyrdaegillvyditsresfenvkkwveeikrv 100
                 +++vG  a GKt++l++   ++  ++ ++Tig++    +  v+ k++++++wD  Gq++ + l + y+++++gi+ v d ++r+   ++++ ++ + + 
  EEA20475.1  20 ILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVE--T--VEYKNIQFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRDRIVEAREELQRMLNE 113
                 899*******************9976.9***87654..4..456799************************************9999999666666655 PP

                 ST.TTSEEEEEEETTTGGG...G-SS-HHHHHHHHHHHTSEEEEEBTTTTCTHHHHHHHHHHH CS
         Ras 101 ae.envpivLvGnKvDlee...kravsteegeelakelglkfletSAktnenveeafeellre 159
                  e ++  +++ +nK Dl +     +++++ g +   +       t A t  ++ e +e l+++
  EEA20475.1 114 DElRDALLLVFANKQDLPNamsIAEITQQLGLQSLTRRAWYIQSTCATTGDGLYEGLEWLAET 176
                 55688999999*******944444555566655555555555567777777777777777666 PP

>> G-alpha  G-protein alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.0   3.7e-05     0.084      21      45 ..      15      39 ..       6      44 .. 0.88
   2 !   37.1   0.5   8.6e-13   1.9e-09     185     280 ..      45     129 ..      35     133 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 3.7e-05
                ..EEEEEEEESTTSSHHHHHHHHHH CS
     G-alpha 21 krevkllllGqseSGKsTilkqlkl 45
                k+e+++l++G +  GK+Til +lkl
  EEA20475.1 15 KKEMRILMVGLDAAGKTTILYKLKL 39
                569*****************99985 PP

  == domain 2  score: 37.1 bits;  conditional E-value: 8.6e-13
                 -----SEEEEEEECT-TEEEEEEEE-SSHHHHHGTCCCTTTECEEEEEEEGGGTT-B-SS-TTSBHHHHHHHHHHCCCC-GGGTTSEEEEEEE-HH CS
     G-alpha 185 rlktvGisetkfevdsklefrivdvgGqrserkkWvpffddvdaiiFlvslsefdqvlyedekvnrleeslklFkeicnnkllkntpiiLflnKlD 280
                  ++t+G++  ++e++ +++f+++dvgGq + r+ W ++f++++ iiF+v   + d          r+ e+ +  + ++n+ +l+++ +++f nK D
  EEA20475.1  45 TIPTIGFNVETVEYK-NIQFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRD----------RIVEAREELQRMLNEDELRDALLLVFANKQD 129
                 47899*999999999.********************************9955554..........5555555555556666666666666666665 PP

>> Gtr1_RagA  Gtr1/RagA G protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.9   0.0   1.3e-13     3e-10       1     135 [.      19     142 ..      19     162 .. 0.86

  Alignments for each domain:
  == domain 1  score: 39.9 bits;  conditional E-value: 1.3e-13
   Gtr1_RagA   1 kvLLmGksgsGKtsmrsiiFdnylardtlrlgatidveksevrflgnltlnlwDcgGqeafveeylssqkeeifrnvgvliyVfDvesre.leedletl 98 
                 ++L++G   +GKt++      ++   ++++   ti  + ++v  ++n+++ +wD+gGq+++          + f+n + +i+V+D+++r+ + e+ e+l
  EEA20475.1  19 RILMVGLDAAGKTTI----LYKLKLGEIVTTIPTIGFNVETV-EYKNIQFTVWDVGGQDKIRPLW-----RHYFQNTQGIIFVVDSNDRDrIVEAREEL 107
                 589**********85....5678889999999**********.599*************987664.....899**************997799999999 PP

   Gtr1_RagA  99 keilealrqyspeakvfvlihKmDliqedereeifee 135
                 +++l++  +  ++a + v+ +K Dl + +  +ei ++
  EEA20475.1 108 QRMLNE--DELRDALLLVFANKQDLPNAMSIAEITQQ 142
                 999985..667999999*******9888777777665 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.2   0.0   2.9e-09   6.4e-06       1     110 [.      19     122 ..      19     127 .. 0.72

  Alignments for each domain:
  == domain 1  score: 26.2 bits;  conditional E-value: 2.9e-09
                 EEEEEESTTSSHHHHHHHH.HTSTEEESSSTTSSSSEEEEEEEETTEEEEEEECGGCSSHHHHHH.HHHHHHHHHHCTSEEEEEEETT.TTCSHHHHHH CS
    MMR_HSR1   1 evaivGrpNvGKStLinal.tgekaivsdkpgtTrdinegrvklkgkeielvDtpGliegaseek.glgkaflaleeadlillvvdas.eeklkpldee 96 
                 +++ vG   +GK+t++ +l +g   iv+ +p  T+  n ++v++k+ +++++D+ G  +    +   l +++ +  +++ i++vvd++ ++ + + +ee
  EEA20475.1  19 RILMVGLDAAGKTTILYKLkLG--EIVTTIP--TIGFNVETVEYKNIQFTVWDVGG-QD----KIrPLWRHYFQ--NTQGIIFVVDSNdRDRIVEAREE 106
                 5889***************444..5788787..7777777777779**********.43....22357777775..578*******7764467778899 PP

                 HHHHHHH..TTSEEEE CS
    MMR_HSR1  97 leellee..akkplil 110
                 l+++l+e   ++ l+l
  EEA20475.1 107 LQRMLNEdeLRDALLL 122
                 9999877542222333 PP

>> 6PF2K  6-phosphofructo-2-kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.1   1.2e-05     0.028      12      51 ..      16      55 ..      10      68 .. 0.83
   2 ?   -0.7   0.0      0.33   7.4e+02      90     135 ..      80     127 ..      71     141 .. 0.75

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.2e-05
                S-EEEEEESSTTSSHHHHHHHHHHHHHHTT--EEEEEHHH CS
       6PF2K 12 sklvivlvGLpargKtyiskkltrylkwlgvrtkvFnvgk 51
                +++ i++vGL a gKt+i  kl      ++++t  Fnv  
  EEA20475.1 16 KEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVET 55
                56789***************99877778888888888865 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.33
                 HHHHTS--SEEEEES---SH..HHHHHHHHHHHHTT-EEEEEEEE--H CS
       6PF2K  90 aylneeegqvaifDAtNttr..erRklilefveennlkvlflesicsd 135
                 +y+++ +g + + D     r  e R+ + ++++e +l+  +l ++++ 
  EEA20475.1  80 HYFQNTQGIIFVVDSNDRDRivEAREELQRMLNEDELRDALLLVFANK 127
                 789999999999998776664467888888888877776666555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (183 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       655  (0.036533); expected 358.6 (0.02)
Passed bias filter:                      562  (0.0313459); expected 358.6 (0.02)
Passed Vit filter:                        73  (0.00407162); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 1242.53
//
Query:       EEA20476.1  [L=571]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.085   12.9   0.0       0.33   11.0   0.0    2.0  2  HTH_35    Winged helix-turn-helix DNA-binding
        0.1   12.1   1.5       0.26   10.8   1.5    1.6  1  SieB      Super-infection exclusion protein B
       0.14   11.4   5.3       0.94    8.7   0.6    2.4  2  CorA      CorA-like Mg2+ transporter protein


Domain annotation for each model (and alignments):
>> HTH_35  Winged helix-turn-helix DNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   5.6e-05      0.33      14      49 ..      73     108 ..      71     117 .. 0.93
   2 ?   -3.0   0.0       1.3     8e+03      17      29 ..     406     418 ..     404     427 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 5.6e-05
      HTH_35  14 rgttLaalsreaglssstlsnaltrpwpkgEalIAe 49 
                 +  +L+al+ ++gls   ++ + t p+++ E+++Ae
  EEA20476.1  73 KDQSLQALANQYGLSYRLVKMMCTDPVRQMETAVAE 108
                 6789*******************************7 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.3
      HTH_35  17 tLaalsreaglss 29 
                 ++a++sr +++  
  EEA20476.1 406 SMADVSRPYDYTA 418
                 899****999865 PP

>> SieB  Super-infection exclusion protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   1.5   4.4e-05      0.26       3      58 ..     478     539 ..     477     556 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 4.4e-05
        SieB   3 aLiiasglllllPdsllekln......lgkfleeyglwiglvflisiayllaqvvskllaei 58 
                 ++++a +++++lP sl+          +g  l+  ++wi +++l+++++++  ++ +l++++
  EEA20476.1 478 TILLAKATIMFLPVSLMSQYFsiqipdIGGPLSLRAYWISFAVLMVLSISILTLFGYLSDTV 539
                 5788999********99765558888999**********************99999998655 PP

>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.6   0.00016      0.94     104     209 ..     291     396 ..     261     398 .. 0.78
   2 ?    4.6   0.4    0.0029        17     225     286 ..     469     529 ..     405     535 .. 0.52

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00016
        CorA 104 kpkspgellyrlldeivdrlfellekle...eeldeledeledstkkeilrelaqlrrrlvklrralapnrevlkrllakaddkllddedkeylrdlld 199
                 + + pg +ly  +d  v +++ + +  +   + ldel +++ ++ + +++++l  l rrl+ l++     + v++r+l++ +  + ++++   +r+   
  EEA20476.1 291 QEDGPGLILYYMFDDWVSSYRLVARREHrygALLDELRQNMLTKPNVDLVDDLHWLGRRLAILKHLYQSYELVITRILQRQRVLRDEAAQ---IRRENR 386
                 56778888888888888888888876441115799999999**************************************44444444444...776666 PP

        CorA 200 elerllemle 209
                 + ++++++le
  EEA20476.1 387 RNTNVSNDLE 396
                 6666666665 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.0029
        CorA 225 llserlNrvmkvLTvltaiflPlTlitGiyGmNfkg..lPelewsygypfvlllglmallaill 286
                 +  e+l r+  +L+  t++flP +l++ ++   ++    P     y+   + + +lm+l+  +l
  EEA20476.1 469 QAVEKLTRITILLAKATIMFLPVSLMSQYFSIQIPDigGPLSLRAYW---ISFAVLMVLSISIL 529
                 22333555555666677788999999999999998622443333332...22223333332222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (571 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       531  (0.0296168); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.30s 00:00:00.89 Elapsed: 00:00:00.46
# Mc/sec: 3727.61
//
Query:       EEA20477.1  [L=217]
Description: 60S ribosomal protein L1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.3e-44  152.4   0.1    1.5e-44  152.2   0.1    1.0  1  Ribosomal_L1  Ribosomal protein L1p/L10e family
  ------ inclusion threshold ------
      0.037   12.7   0.0      0.051   12.3   0.0    1.1  1  SNF           Sodium:neurotransmitter symporter family


Domain annotation for each model (and alignments):
>> Ribosomal_L1  Ribosomal protein L1p/L10e family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  152.2   0.1   1.6e-48   1.5e-44       4     204 .]      23     212 ..      16     212 .. 0.95

  Alignments for each domain:
  == domain 1  score: 152.2 bits;  conditional E-value: 1.6e-48
                   HS-SSS--EEEEEEEESSS-TTSGGG--EEEEE-STSTSSCS-EEEEE-HHHHH...HHHHTT..-SEEETCHHHHHHT-HHHHHHTCCH-SEEEEE CS
  Ribosomal_L1   4 hakkkfdesveialnlttkkpkkadqrkpgkipLphplgkevkiclitkdpqaeyakeakeagriakviglkklkkkyksfeakrkllkefdlflad 100
                   ++k++f e+ve+++ l++++p++ d+r++g+i Lp+  +  +++c+i ++++ +    ak+ g   +  ++++lkk  k+++  +kl+ ++d f+a+
    EEA20477.1  23 TKKRNFLETVELQIGLKNYDPQR-DKRFSGTIRLPNVPRPGMSVCIIGDQHDLD---RAKHLG--LESASVDDLKKLNKNKKLIKKLARKYDAFVAS 113
                   4478899*************666.99************************9999...9*****..******************************** PP

                   GGGHHHHHHHCHHHHGGGT-S-ECC..CT.BTS-HHHHHHHHCTTEEEEE-TTTSEEEEEEEETTSSHHHHHHHHHHHHHHHHHTSTTTSGSEEEEE CS
  Ribosomal_L1 101 drimpllpklLGkvfgkrkkmPipvltkgtvkedvkkevekalkstvvvrldkgtclsvkvGklsftaeelaeNieavvkalvekvpkkwkniksiy 197
                   d +++++p++LG+ ++ ++k+P+p  ++    ed+ ++v ++++ t++++l+k  cl v+vG++++t++el++Ni+ ++++lv+ ++k+w+n+ s++
    EEA20477.1 114 DTLIKQIPRILGPGLSRAGKFPTPL-SH---AEDMDAKVTEVKS-TIKFQLKKVLCLGVAVGNVGMTEDELISNIMLAINYLVSLLKKGWQNVGSLV 205
                   *************************.43...68***********.**************************************************** PP

                   EEETTS- CS
  Ribosomal_L1 198 lkttmsp 204
                   +k +msp
    EEA20477.1 206 IKASMSP 212
                   ******8 PP

>> SNF  Sodium:neurotransmitter symporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   5.7e-06     0.051     146     213 ..     146     212 ..     134     214 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 5.7e-06
         SNF 146 enltekssaaeefwerevlklsssieelGelrweltlcllvawvvvylailkGvkssgkvvyftatfP 213
                 +++t +++++++f  ++vl l   + ++G+ + el+  +++a+  ++  + kG +++g++v  +++ P
  EEA20477.1 146 AKVT-EVKSTIKFQLKKVLCLGVAVGNVGMTEDELISNIMLAINYLVSLLKKGWQNVGSLVIKASMSP 212
                 3444.678899********************************999999**********998887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (217 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       589  (0.0328518); expected 358.6 (0.02)
Passed bias filter:                      459  (0.025601); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.29s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 1520.24
//
Query:       EEA20478.1  [L=431]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (431 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       644  (0.0359195); expected 358.6 (0.02)
Passed bias filter:                      461  (0.0257125); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.55u 0.23s 00:00:00.78 Elapsed: 00:00:00.40
# Mc/sec: 3208.40
//
Query:       EEA20479.1  [L=474]
Description: proline-rich, actin-associated protein Vrp1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-09   37.1   0.7    3.4e-09   36.2   0.1    1.8  2  WH2       WH2 motif
  ------ inclusion threshold ------
      0.018   14.6  14.2      0.018   14.6  14.2    9.3  7  CAP_N     Adenylate cyclase associated (CAP) N terminal


Domain annotation for each model (and alignments):
>> WH2  WH2 motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2   0.1   3.8e-13   3.4e-09       1      30 []      39      66 ..      39      66 .. 0.97
   2 ?   -3.0   0.1      0.86   7.7e+03       3       8 ..     399     404 ..     398     404 .. 0.85

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 3.8e-13
                X-TCCHHHHHHHHHH...HTTBSS--XEEXX CS
         WH2  1 ggggRgALLadIraGs.kaqLKKveetndrs 30
                ggg+R+AL+adI++G+ k  L+K+ +tndrs
  EEA20479.1 39 GGGNRNALFADINKGVpK--LRKA-VTNDRS 66
                79****************..****.*****8 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.86
                 TCCHHH CS
         WH2   3 ggRgAL 8  
                 +gR+AL
  EEA20479.1 399 QGRSAL 404
                 79***9 PP

>> CAP_N  Adenylate cyclase associated (CAP) N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?  -13.6  23.1         2   1.8e+04     247     257 ..       3      13 ..       1      16 [. 0.42
   2 ?   14.6  14.2     2e-06     0.018     244     287 ..      15      54 ..      11      67 .. 0.64
   3 ?   -5.5   5.6         2   1.8e+04     238     260 ..      75     104 ..      56     127 .. 0.41
   4 ?  -41.8  51.2         2   1.8e+04     268     268 ..     205     205 ..     151     261 .. 0.57
   5 ?  -43.1  59.0         2   1.8e+04     243     271 ..     257     282 ..     249     326 .. 0.64
   6 ?   -9.2  19.9         2   1.8e+04     242     256 ..     330     348 ..     311     354 .. 0.39
   7 ?  -11.4  21.5         2   1.8e+04     240     261 ..     352     376 ..     348     395 .. 0.44

  Alignments for each domain:
  == domain 1  score: -13.6 bits;  conditional E-value: 2
                 ....XXXXXXX CS
       CAP_N 247 pppPpPpPppa 257
                 pppPpPpPpp+
  EEA20479.1   3 PPPPPPPPPPP 13 
                 23333333443 PP

  == domain 2  score: 14.6 bits;  conditional E-value: 2e-06
                 XXX....XXXXXXXX.....XXXXXXXXXXXXXXXXXXXXXXXX CS
       CAP_N 244 aggpppPpPpPppasvfeeesaaasasaaaggmsavFaeLnkGe 287
                  gg ppPpPpPpp        a++++s+ +g+++a+Fa++nkG 
  EEA20479.1  15 MGG-PPPPPPPPPGGG---MPARPAKSSGGGNRNALFADINKGV 54 
                 334.444444444443...344578999***************4 PP

  == domain 3  score: -5.5 bits;  conditional E-value: 2
                 --XXXXXXX....XXXX..........XXXX.. CS
       CAP_N 238 aasaaaaggpppPpPpP..........ppasvf 260
                 ++  ++ gg   +pP P          pp + +
  EEA20479.1  75 KSGGPPIGG---APPVPgmpkgpgglaPPIPSA 104
                 222222233...233222223334443322222 PP

  == domain 4  score: -41.8 bits;  conditional E-value: 2
                 X CS
       CAP_N 268 s 268
                 +
  EEA20479.1 205 N 205
                 0 PP

  == domain 5  score: -43.1 bits;  conditional E-value: 2
                 XXXX....XXXXXXXX.....XXXXXXXX CS
       CAP_N 243 aaggpppPpPpPppasvfeeesaaasasa 271
                 +a ++ppPpPpPppasv     a +sa+ 
  EEA20479.1 257 TAPSAPPPPPPPPPASVS---PAPPSAPP 282
                 222233444444455443...22233333 PP

  == domain 6  score: -9.2 bits;  conditional E-value: 2
                 XXXXX........XXXXXX CS
       CAP_N 242 aaagg..ppp..PpPpPpp 256
                   +++  p+p  PpPpPpp
  EEA20479.1 330 FGNSHnpPAPptPPPPPPP 348
                 2222211222113333333 PP

  == domain 7  score: -11.4 bits;  conditional E-value: 2
                 XXXXXXX....XXXX.XXXX..... CS
       CAP_N 240 saaaaggpppPpPpP.ppasvf..e 261
                 ++ + +gpppPpPp  ppa ++  +
  EEA20479.1 352 PSLPVSGPPPPPPPTsPPALAPpgR 376
                 3444455333333321333222221 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (474 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       350  (0.0195214); expected 358.6 (0.02)
Passed bias filter:                      129  (0.00719505); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                        18  (0.00100396); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.83u 0.28s 00:00:01.10 Elapsed: 00:00:00.50
# Mc/sec: 2878.76
//
Query:       EEA20480.1  [L=98]
Description: small nuclear ribonucleoprotein Lsm8, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.8e-17   60.6   0.1    1.4e-16   59.9   0.1    1.3  1  LSM       LSM domain


Domain annotation for each model (and alignments):
>> LSM  LSM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.9   0.1   7.7e-21   1.4e-16       3      64 ..       3      70 ..       1      73 [. 0.95

  Alignments for each domain:
  == domain 1  score: 59.9 bits;  conditional E-value: 7.7e-21
                HHHTTTSEEEEEETTSEEEEEEEEEEETTSEEEEEEEEEEETTET......EEEEEEEEEEEGGGEEE CS
         LSM  3 lkklinkkvtvelkngrelrGtLkgfDqfmNlvLedveetlkdkk......ekrklglvliRGnnivl 64
                l+++inkk++v++ +gr+l GtL + Dq  NlvL++++e++  +       ++   gl+liRG+n+v+
  EEA20480.1  3 LSSYINKKILVITVDGRTLLGTLLSTDQLTNLVLTQTVERIIRTPedpepsSEIEHGLYLIRGDNVVV 70
                899*************************************9888899*******************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (98 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       348  (0.0194099); expected 358.6 (0.02)
Passed bias filter:                      298  (0.0166211); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.27s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 713.54
//
Query:       EEA20481.1  [L=419]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (419 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       610  (0.0340231); expected 358.6 (0.02)
Passed bias filter:                      387  (0.0215851); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.24s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 3011.45
//
Query:       EEA20482.1  [L=861]
Description: HLH transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.6e-14   51.4   0.6    1.5e-13   50.5   0.6    1.5  1  HLH       Helix-loop-helix DNA-binding domain


Domain annotation for each model (and alignments):
>> HLH  Helix-loop-helix DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.5   0.6   8.2e-18   1.5e-13       1      53 []     563     614 ..     563     614 .. 0.97

  Alignments for each domain:
  == domain 1  score: 50.5 bits;  conditional E-value: 8.2e-18
                 HHHHHHHHHHHHHHHHHHHHHHHHHCSTCSTTSS-STHHHHHHHHHHHHHHHH CS
         HLH   1 rraahnerErrRRdriNsaleeLrellPslppskKlsKaeiLekAveYIkhLq 53 
                 r++ah+++ErrRR ++N+ +++L++++P + +++ + K +iL+  ++Y+++L+
  EEA20482.1 563 RKTAHSLIERRRRSKMNEEFATLKDMIP-ACRGQEMHKLAILQASIDYMNYLE 614
                 79**************************.99********************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (861 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1438  (0.0802053); expected 358.6 (0.02)
Passed bias filter:                      391  (0.0218082); expected 358.6 (0.02)
Passed Vit filter:                       141  (0.00786435); expected 17.9 (0.001)
Passed Fwd filter:                        64  (0.00356964); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 1.73u 0.41s 00:00:02.14 Elapsed: 00:00:00.69
# Mc/sec: 3787.69
//
Query:       EEA20483.1  [L=422]
Description: nucleoside hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      5e-59  200.4   0.0    7.1e-59  199.9   0.0    1.1  1  IU_nuc_hydro     Inosine-uridine preferring nucleoside hydrol
  ------ inclusion threshold ------
      0.056   13.3   0.0       0.11   12.4   0.0    1.4  1  Transketolase_C  Transketolase, C-terminal domain


Domain annotation for each model (and alignments):
>> IU_nuc_hydro  Inosine-uridine preferring nucleoside hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  199.9   0.0   7.9e-63   7.1e-59       2     287 ..       5     377 ..       4     395 .. 0.77

  Alignments for each domain:
  == domain 1  score: 199.9 bits;  conditional E-value: 7.9e-63
                   EEEEEE--SHHHHHHHHHHHCT.HTTEEEEEEEE-SSSS-HHHHHHHHHHHHHHHCT..................TT.S-EE.EE-SS-SSSSS-SH CS
  IU_nuc_hydro   2 kvilDtDpGiDDalAlllalae.speiellgittvaGnvsleqatrnalrvlealgg..................rddipvy.aGaekpllrekaaa 78 
                   k+i+DtDpGiDD+lA+lla a+  +e+e+l ++ ++Gn +++   rn++++l ++++                  r + pv+ +Gae+pl  +k  a
    EEA20483.1   5 KIIIDTDPGIDDILAMLLAFAAsPEEVEVLLVSLTFGNIEVHSCLRNVVSML-HILEremdwrkkqgrpegfdtlRAHKPVIaVGAEQPLDDQKMLA 100
                   8******************6654689**************************.777779****************777897769*****87775555 PP

                   H.HHTTTSSTSS-.--SSH.................................CSCSSHHHHHHHHHHHHCHHTTTT.EEEEECS-SHHHHHHHHHTC CS
  IU_nuc_hydro  79 e.ihGedGlgdvllpeper.................................kaesesavdalidaveaareypge.vtlvatGplTNiAlalrldp 140
                   + +hG+dGlg+++ + p+                                   +++  a+d + + +   re++++ vt+va+GplTN+Ala ++dp
    EEA20483.1 101 DyFHGKDGLGGIHFSHPHLtpgetwehlfdpisdpevlpnvgpspseshksfIPSKLPAADEILRVL---RENEENtVTIVAVGPLTNLALAAAKDP 194
                   55*******9773333322334555666666667777788887766666666555555666666777...6666656******************** PP

                   CHHHHEEEEEEE---SSS--SSSSSS-HHHHHSHHHHHHHHHT...S-E.....................EEEE-HHHHTTSCHEECHHHHHH.... CS
  IU_nuc_hydro 141 elakkvkrlviMGGaftarGNvtpvaEfNifvDPeAAkiVles...apv....................kitlvpldvthkvqalltseevee.... 210
                   e   +vk++v+MGG+++++GNvtpv EfN ++D  AA++V+     +p+                     + l+pld+t+++   l + ++++    
    EEA20483.1 195 ETFLRVKEVVVMGGTINEPGNVTPVGEFNSYADAVAAARVFALtspNPQstlppskilppypaklsktlTLKLFPLDITSQHD--LIRGDFDRtitp 289
                   *****************************************66867333667777889999999999999999******9555..344333332212 PP

                   HHCSTCBHHH..HHHHHHHHHHHHHHHHHH.....SSEEE-HHHHHHHHHH-.......GGGEEEEEEEEEEESSSSTTTTEEEEETSTT.T CS
  IU_nuc_hydro 211 laalekglga..fladllefyikaykeaeg.....sdgaplhDplavavald.......pelvttkrlavdveleggltrGrtvvdlrrl.k 287
                   l +   g++    + +++ +++++ ++ ++     ++   lhDp++v++a+        p+  +t++ ++++e+ g+ trG++vvd+r++ k
    EEA20483.1 290 LLQS--GSPLaeWVDAFMAHVFQTLERLHPghegaKASLTLHDPVCVWYAMTsddprwkPT--STSPEDIRIETVGQWTRGMCVVDRRNRhK 377
                   3333..333122344455555555555555888899*************986455333322..336788999*************9998751 PP

>> Transketolase_C  Transketolase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   1.2e-05      0.11       3      30 ..     166     193 ..     164     197 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 1.2e-05
                      EEEEETTSSEEEEEETTHHHHHHHHHHH CS
  Transketolase_C   3 aeilregkdvtlvayGsmveealeAaee 30 
                      + +++e++ vt+va+G   + al+Aa++
       EEA20483.1 166 VLRENEENTVTIVAVGPLTNLALAAAKD 193
                      55678899******************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (422 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       405  (0.0225891); expected 358.6 (0.02)
Passed bias filter:                      389  (0.0216967); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 3003.03
//
Query:       EEA20484.1  [L=389]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (389 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3096  (0.172681); expected 358.6 (0.02)
Passed bias filter:                      866  (0.0483016); expected 358.6 (0.02)
Passed Vit filter:                       154  (0.00858944); expected 17.9 (0.001)
Passed Fwd filter:                        54  (0.00301188); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 1.21u 0.39s 00:00:01.60 Elapsed: 00:00:00.56
# Mc/sec: 2075.71
//
Query:       EEA20485.1  [L=359]
Description: proline utilization protein PrnX, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.4e-14   53.7   0.0    3.7e-07   29.4   0.0    2.0  2  OCD_Mu_crystall  Ornithine cyclodeaminase/mu-crystallin famil
    0.00013   22.1   0.0        1.1    9.4   0.0    3.1  3  Shikimate_DH     Shikimate / quinate 5-dehydrogenase


Domain annotation for each model (and alignments):
>> OCD_Mu_crystall  Ornithine cyclodeaminase/mu-crystallin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.4   0.0   4.2e-11   3.7e-07      26     172 ..      33     186 ..      10     210 .. 0.75
   2 !   22.5   0.0     5e-09   4.5e-05     193     317 ..     227     350 ..     216     351 .. 0.85

  Alignments for each domain:
  == domain 1  score: 29.4 bits;  conditional E-value: 4.2e-11
                      HHHHHHHCC...-CE----EEEEECCGTEEEEEEEEEETTTTEEEEEEEEEETTTCCC.TSSSEEEEEEEE-TTT--EEEEEE-HHHHHHHHHH CS
  OCD_Mu_crystall  26 eafrrlasg...kvkkpprvalevkdsrgelevmpaylagrellgvKlvnshpenkks.glptvtalvvLndpetGvplalmdatlltalRTaA 115
                       af +  +    ++++ppr+   +++       mp ++ +  ++g+K+v++ +  + + g+  v+    +++p  G    +m+a  +ta RTa 
       EEA20485.1  33 SAFSAQRKTkdvNIHQPPRTSIVSEKWSATTLFMPVSDHA--STGFKVVTVPKVSTPTnGIRGVIN---ILSP-EGRLEGVMSAAEITAFRTAL 120
                      34433333366699**************************..*******99544333326555544...3455.699***************** PP

                      HHHHHHHHHS-TT--E.....EEEE--SHHHHHHHH....HHCCCS--SEEEEE-SSHHHHHHHHH CS
  OCD_Mu_crystall 116 vsavaakyLarkdasv.....laiiGaGvqaetqle....alkavldikevriydrdeeaaekfae 172
                      +s +      +++++v     + i+G G qae +++     + +  di+ v   +r+++  e  ++
       EEA20485.1 121 ASMIPFTRFCQQSSEVgkkkrILIFGSGKQAEWHARlallTVPESTDIESVTFVNRSQRRLEESIS 186
                      ****9777777777653333389********99876211134566789999999999999887665 PP

  == domain 2  score: 22.5 bits;  conditional E-value: 5e-09
                      TSSEEEE----SS-SB-GGGS-TT...-EEEE-S--STT--SB-HHHHH...CCEEEE.SHHHHHHHCCCCHCHHHTTSSTCGGEEEEHHHHHC CS
  OCD_Mu_crystall 193 gadivvtvTaakapilkaewvkpG...ahinavgadapgkteLdddilk...radifv.dseaqareeGeiqvaiekgvlaedakvaelgevia 279
                        d +  +T++++p+++ + + +     +i ++g+  p+ +e+d   l+   +  i+v + ea  +e Ge+ +      + e+++  elge  +
       EEA20485.1 227 SSDALFCCTPSTEPLFTYDDLTATpkrRYISLIGSYKPHMQEIDSRTLLsgnKEMIYVdSVEACIEEAGELIM-----AKVEEKQLIELGELDS 315
                      5678899**********999987533379****************99972224569996678889******99.....78899999*****988 PP

                      TSS-..-STTSEEEEE----HHHHHHHHHHHHHHHCCC CS
  OCD_Mu_crystall 280 GkkpGRtsdeeitlfdsvGlaveDvaaaklvyeraeek 317
                             + e  ++f+ vG+++ D+++a+   e a+e+
       EEA20485.1 316 SSSL---DGEGNVVFKCVGMGIMDLVIARSLLEMAREQ 350
                      7766...788889****************999999875 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.3   0.0   0.00025       2.2       9      51 ..     136     183 ..     129     202 .. 0.77
   2 !    9.4   0.0   0.00012       1.1      68     102 ..     220     254 ..     207     260 .. 0.87
   3 ?   -0.2   0.0       0.1   9.2e+02      61      98 ..     279     316 ..     265     328 .. 0.80

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00025
                   ..TT-EEEEES-SHHHHHHHH.HHH....CCT-CEEEEEESSHHHHHH CS
  Shikimate_DH   9 slkekkvlliGaGemaelvak.hLl....akgvkkvvvaNRtlerake 51 
                     k+k++l+ G G+ ae  a+ +Ll    +  +++v+ +NR+++r +e
    EEA20485.1 136 VGKKKRILIFGSGKQAEWHARlALLtvpeSTDIESVTFVNRSQRRLEE 183
                   45899**********99887733432332458999********99876 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.00012
                   GHHHHHHT-SEEEE-SSSSS-SB-HHHHHCCHHH. CS
  Shikimate_DH  68 elkellaeadvvisataseepilekeeveealkkr 102
                    l++ la++d ++++t s+ep+++ ++++++ k+r
    EEA20485.1 220 RLRADLASSDALFCCTPSTEPLFTYDDLTATPKRR 254
                   678899**********************9998876 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 0.1
                   -EEEEGCGHHHHHHT-SEEEE-SSSSS-SB-HHHHHCC CS
  Shikimate_DH  61 iealkleelkellaeadvvisataseepilekeeveea 98 
                    e++ +++++++++ea  +i+a   e+ ++e +e+ ++
    EEA20485.1 279 KEMIYVDSVEACIEEAGELIMAKVEEKQLIELGELDSS 316
                   56788899999999999999999999999988877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (359 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       439  (0.0244855); expected 358.6 (0.02)
Passed bias filter:                      402  (0.0224218); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2346.52
//
Query:       EEA20486.1  [L=824]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-12   47.5   0.0    2.4e-12   46.5   0.0    1.5  1  Fungal_trans  Fungal specific transcription factor domain
    9.2e-09   35.3  11.7    1.7e-08   34.5  11.7    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
       0.19   11.5   1.1       0.31   10.8   0.1    1.7  2  DUF4769       Domain of unknown function (DUF4769)
        4.7    6.5   8.0         87    2.4   0.0    2.2  2  NBP1          Fungal Nap binding protein NBP1


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.5   0.0   5.3e-16   2.4e-12      11     265 ..     216     450 ..     206     452 .. 0.81

  Alignments for each domain:
  == domain 1  score: 46.5 bits;  conditional E-value: 5.3e-16
  Fungal_trans  11 qfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLlllelyekts 107
                    +p+lh+p+f  + ++  + + +  +++ l +++a+ ++ ++ e++               ++l+a  ++  + s +  +l +lq+L l++ y++ +
    EEA20486.1 216 MLPVLHEPTFRQDAEDVFRASQDPIQNFQLRMVVAISMQKLSPEYAGL------AD----SYYLAALPFL--QPSLQQMDLRSLQCLTLIAQYSLIT 300
                   5799**********7777778888899999999999999999999997......22....4678******..777777789**************** PP

  Fungal_trans 108 sdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrpp..llddsqinlpLPcddddlwesddaseet 202
                    +r++ + ++g a +la++lgL ++ +  +++++  l + e  +rrR++w +  ++  +a  lGrp+   ++ + +n+ +P   dd  ++ +     
    EEA20486.1 301 PTRTASYWVVGAAAKLAQELGLLEEANITKSTTGEPLNVLEVDMRRRVAWVVITMEFGLAHSLGRPNafCISHDHLNIGFPQLVDDRFITAQGILPG 397
                   ******************************9999999999999************************987***********9999766666655555 PP

  Fungal_trans 203 lvetklsneeksrkiasfllaLkkilskiagsllsiekqlqqrdlqseklswveeleraldnW 265
                    +        + +  a  ++++  +++++ ++l+ ++ +   +d++    +w+e++  ++d W
    EEA20486.1 398 AKP------IWAKCTAIHFFKMRLLQAEVRRTLYLNKREAPVNDQD----PWFEQIMAKIDDW 450
                   555......5666667777777766777777555555555544444....7777777777777 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.5  11.7   3.7e-12   1.7e-08       1      35 [.      39      73 ..      39      77 .. 0.90

  Alignments for each domain:
  == domain 1  score: 34.5 bits;  conditional E-value: 3.7e-12
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCT CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfyse 35
                +aC++Cr++K++Cd ++P C  C+++n+ C++y+ 
  EEA20486.1 39 TACTRCRQRKSRCDPGIPRCEPCERSNARCVYYDS 73
                69*****************************6654 PP

>> DUF4769  Domain of unknown function (DUF4769)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.1      0.72   3.2e+03     203     221 ..      68      85 ..      25     107 .. 0.74
   2 ?   10.8   0.1   6.9e-05      0.31      42     141 ..     543     649 ..     536     678 .. 0.68

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.72
     DUF4769 203 csyyednqlhltlqrshll 221
                 c yy+    h t+ rs+++
  EEA20486.1  68 CVYYDST-RHQTISRSYIV 85 
                 6666444.47777777754 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 6.9e-05
     DUF4769  42 irfehhlerWrrwlnvPlqgvqgqgaghcsGcrcaeilvqsqeqasevaesessleeskkpe.....elvkdlpaeplvslneevesssvleamq...p 132
                 ir eh +e  + +l + l+ v  +++    Gc+ a +l +s  +a+  a  + +    ++p       +v+d+++ p++s    + ++sv+++++    
  EEA20486.1 543 IRIEHDIEEVKSYLQIALEAVAISAQ-RWPGCESALQLYKSLMTACLKAYDTAESFVVHTPStqpspASVQDITTPPFISSPSATSHHSVQTVVTaatT 640
                 9*******************999988.899***********9887776666665555555541111145677888888887776666666444430003 PP

     DUF4769 133 llepsells 141
                 ++++++ ls
  EEA20486.1 641 TSDTEKYLS 649
                 344444433 PP

>> NBP1  Fungal Nap binding protein NBP1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0      0.02        87     173     212 ..      63     106 ..      42     113 .. 0.82
   2 ?    2.2   7.3     0.022        97     264     332 ..     606     683 ..     596     689 .. 0.73

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.02
        NBP1 173 kserr....vslrnnnleeDqvvlLqkkikklesklkdlekeLe 212
                 +s++r    +s+r++ +    +v+L+ + + le++++++eke +
  EEA20486.1  63 RSNARcvyyDSTRHQTISRSYIVQLRERARALEREIEAAEKEVR 106
                 44444666678899999999*********************986 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.022
        NBP1 264 pspkr...tvnplftSSPmrkenteeeekse.vgekktdefYnkYpkipeteeLkk.....kddeddkeeeSLSPiri 332
                 psp +   ++ p f SSP  +++++ ++      +++ +e Y   ++ p+te L+k     +++++  ++ S SPi +
  EEA20486.1 606 PSPASvqdITTPPFISSPSATSHHSVQTVVTaATTTSDTEKYLSHSRGPSTEPLQKhtpvhEQSNTPASQPSSSPIYM 683
                 44444335889********98776655555544445555667777999********9999888899999999999976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (824 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       965  (0.0538234); expected 358.6 (0.02)
Passed bias filter:                      637  (0.035529); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.72u 0.31s 00:00:01.03 Elapsed: 00:00:00.45
# Mc/sec: 5442.40
//
Query:       EEA20487.1  [L=634]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.8e-18   65.5   0.1    5.6e-18   64.9   0.1    1.2  1  Fungal_trans  Fungal specific transcription factor domain
    7.7e-08   32.3   8.0    7.7e-08   32.3   8.0    2.2  2  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.9   0.1   6.2e-22   5.6e-18       1     239 [.     184     402 ..     184     440 .. 0.89

  Alignments for each domain:
  == domain 1  score: 64.9 bits;  conditional E-value: 6.2e-22
  Fungal_trans   1 ldrffsnfhpqfpilhkpsflpkt...ssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwil 94 
                   ++ +f+n+  q+p++ + +f+++    ++++ + ++  ++ +++++la+++ ++  ++ + n+++  ++   +a pl+ e l+     + ss l  +
    EEA20487.1 184 IQYYFDNILIQLPLFTETTFWTSVeavYQDGGRFAKPIDQWMVYMVLAIASASLWHQQPSVNQQFALSM-VSAAIPLAGEVLQ-----PGSS-LG-I 272
                   689***********************************************9998888888889999888.89999*****999.....5555.76.6 PP

  Fungal_trans  95 qsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcdddd 191
                   q+ lll+ y++   +     +++  a r+  +lgLh++p+ +      +++ e  e+rrRl++a + lD+++++ lG+++ ++d ++++ LP     
    EEA20487.1 273 QAILLLAQYSLFNPEHFRPRYLVFFASRVMIDLGLHQDPPAEV-----VVDRERLEQRRRLFYALYTLDRIVCTSLGHTFSFSDLSVDVDLPIVRVL 364
                   99*************999999********************99.....69***9**************************99**********99999 PP

  Fungal_trans 192 lwesddaseetlvetklsneeksrkiasfllaLkkilskiagsllsie 239
                    ++  +++ + +++          + ++ ++++ +ilsk + ++++ +
    EEA20487.1 365 PGDLPNVNVFMKKS----------DCTTHMIKIRRILSKGYQQMYFDG 402
                   99999999999998..........557888888888888666666655 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.3   8.0   8.5e-12   7.7e-08       2      31 ..      20      51 ..      19      59 .. 0.89
   2 ?   -0.3   0.2      0.14   1.2e+03       5      14 ..     546     555 ..     545     571 .. 0.70

  Alignments for each domain:
  == domain 1  score: 32.3 bits;  conditional E-value: 8.5e-12
                S-HHHHHCT---STSSSS-HHHHHCT..HHHC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkkln..leCt 31
                aC +Cr  K+KCd+k PaCs C+k +  ++C+
  EEA20487.1 20 ACLRCRTAKIKCDGKLPACSACEKAGkaSTCS 51
                9*************************777786 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.14
                 HHHHCT---S CS
     Zn_clus   5 nCrkkKvKCd 14 
                 nCr++  +C 
  EEA20487.1 546 NCRSRAARCL 555
                 6888877774 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (634 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       659  (0.0367561); expected 358.6 (0.02)
Passed bias filter:                      559  (0.0311785); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.26s 00:00:00.86 Elapsed: 00:00:00.40
# Mc/sec: 4721.71
//
Query:       EEA20488.1  [L=435]
Description: hypothetical protein PMAA_043250 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.082   12.9   0.1       0.57   10.2   0.1    2.3  2  DUF5345   Family of unknown function (DUF5345)


Domain annotation for each model (and alignments):
>> DUF5345  Family of unknown function (DUF5345)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0      0.11   2.1e+03       5      20 ..     171     188 ..     170     194 .. 0.82
   2 ?   10.2   0.1   3.2e-05      0.57      25      58 ..     206     237 ..     196     242 .. 0.69

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.11
     DUF5345   5 lerlDqlievet..Psle 20 
                  erlD+ ++ e+  Ps +
  EEA20488.1 171 AERLDEICNAENidPSVA 188
                 69******9999888876 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 3.2e-05
     DUF5345  25 llaeekerkrkrlrrElllFlliAllilslllla 58 
                 + +++++r+rk+++  ++ F+liA++++s+l+l 
  EEA20488.1 206 HCQAKWRRERKAFY--VISFVLIAVTLVSGLILY 237
                 55555666666665..577888888888887775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (435 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       600  (0.0334653); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 2820.94
//
Query:       EEA20489.1  [L=447]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.1e-62  209.6   1.0    6.1e-62  209.6   1.0    1.6  2  Rox3         Rox3 mediator complex subunit
  ------ inclusion threshold ------
      0.046   14.3   1.3       0.12   12.9   1.3    1.8  1  SPT6_acidic  Acidic N-terminal SPT6
      0.069   11.8   7.6       0.11   11.1   7.6    1.3  1  Hamartin     Hamartin protein


Domain annotation for each model (and alignments):
>> Rox3  Rox3 mediator complex subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.3      0.77   4.6e+03     140     161 ..      69      90 ..      48     140 .. 0.65
   2 !  209.6   1.0     1e-65   6.1e-62       3     205 .]     214     421 ..     212     422 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.77
        Rox3 140 kaqsaratapstplaaaeaarp 161
                 + q  ++  +stp++++++++p
  EEA20489.1  69 NGQPLSSPPSSTPMSTQNSQQP 90 
                 3344444455555554444443 PP

  == domain 2  score: 209.6 bits;  conditional E-value: 1e-65
        Rox3   3 rPnpsedLielYgLteiaaeVARtdpvtGeKinkLRKsYkgkikklglsGkfkavkkkeegkegellellklpdeeWqnqkvkgkeiekglsadvlskl 101
                  P+ps dLi+lYgL +i ++V R dp+tGeKin+LRKsY+gk+k lglsG++kav k+e ++ g l++l+++p+eeWq qkv+gkei+ + ++++l+kl
  EEA20489.1 214 GPDPSFDLISLYGLGPIGRSVMRADPTTGEKINRLRKSYEGKLKGLGLSGRNKAV-KNE-NQAGGLRHLMMWPEEEWQIQKVHGKEIKVAEAESALQKL 310
                 7******************************************************.777.78999***********************99999999999 PP

        Rox3 102 e.kalkmakGeipkke.wdasvLgldkdsklksakaas......tkkaqsaratapstplaaa.......eaarpkrkgkKRsYgdssFeGYgegfeDd 185
                 + +a+k++ G++p++e w+ ++Lg++k+sk+++ ++ +      +    + r+t +++            e+ar +r gkKR+Y+d+sF+GYgegf Dd
  EEA20489.1 311 QmRAMKLEAGPLPNSEyWE-DILGHEKSSKHTNVESGKravstpN----TLRPTVQTNG---VpptaaapERARHTR-GKKRHYDDNSFVGYGEGFVDD 400
                 99**************888.*******999998887774433221....2333322222...123344457777777.********************9 PP

        Rox3 186 d....gyStgdgddrgegkkrrkk 205
                 d     yS++++   + gkk+rkk
  EEA20489.1 401 DdegaLYSNSEDR--S-GKKKRKK 421
                 9997777776664..4.6777776 PP

>> SPT6_acidic  Acidic N-terminal SPT6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   1.3   2.1e-05      0.12      12      47 ..     389     422 ..     372     433 .. 0.66

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.1e-05
  SPT6_acidic  12 eerkvregFIvdddeeeeeeeeseeeeekkrrkkkk 47 
                        egF++ddde    +++++  ++ k+++kk+
   EEA20489.1 389 SFVGYGEGFVDDDDEGALYSNSED--RSGKKKRKKE 422
                  5556679*****988765544432..2333333332 PP

>> Hamartin  Hamartin protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   7.6   1.8e-05      0.11     298     397 ..      28     134 ..       9     209 .. 0.65

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 1.8e-05
    Hamartin 298 tkrlqlsslsgtspavlsvessrskddei.slWSPssvcgmttppsspgivptte.lelsssasllsskvsstpeaagkatpe.tTPakssrkl....p 389
                   +++l   + tsp+++sv +++  ++   +  SPs +++   +p s++ + t   +++s++     ++++ tp++++ + p  tTPa +s+ +     
  EEA20489.1  28 GISENLYPHTPTSPPLMSVGAQNYASNFAhTHTSPSHTTTSNGQPLSSPPSSTPMsTQNSQQPTVSVTTSFPTPASSVSGHPRnTTPADDSELAdkswG 126
                 3335677777778888877776655443347899*9888777777666555444447888888888899999*******************85554443 PP

    Hamartin 390 pslsesav 397
                 +  ++s++
  EEA20489.1 127 QGVQNSHA 134
                 33333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (447 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       602  (0.0335769); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.48
# Mc/sec: 2816.01
//
Query:       EEA20490.1  [L=275]
Description: haloalkanoic acid dehalogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    0.00012   22.5   0.0    0.00027   21.3   0.0    1.6  1  Hydrolase  haloacid dehalogenase-like hydrolase
     0.0002   21.5   0.0      0.022   14.8   0.0    2.7  2  HAD_2      Haloacid dehalogenase-like hydrolase
  ------ inclusion threshold ------
       0.16   11.9   2.0       0.87    9.5   0.1    2.3  2  CsbD       CsbD-like


Domain annotation for each model (and alignments):
>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.0   4.5e-08   0.00027       2     196 ..      12     211 ..      11     215 .. 0.70

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 4.5e-08
                 SEEEEESBTTTBCHHHHHHHHHHHH..CHHHHHHHHHH.HHCHHHHHHHHHHHHH..HHHHHHHHHETTTEHHHHTHHHHHHHHHCHHHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxx.xxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase   2 ktvvfDkdGTLttgepsvedvivsa..alalaaaletg.sehpigkalvaaakar..sgaltgfatfigrgayaigkpewltaldippdlgaaigsaqs 95 
                 +++ fD+ GTL++ e+ + +++  +   l+ +  l    ++  +g+ +++    +  + + + + +           ++   a    + lg+  g+ q 
  EEA20490.1  12 RLLSFDIYGTLIDWEKGILQALSPIrdRLPDSSPLKSTeNDLALGNVFTKHEARLqtENPGATYDK---------ILRDAYIAV-AKELLGNGLGDDQL 100
                 6789***********999998888845444444444445555555555444444432222233333.........222222222.22235555666666 PP

                 HCHHHHHHTTHHHHHHHHHHTHHBHTTHHHHHHHHHHTTEEEEEEESSEHHHHH.HHHHHTT.............GGGESEEEEHHCESSTTTSHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxx.............xxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase  96 qgrtvallqaralavftiadplkvkpeaaeavasLkaagievvlltgdnpetae.raanqlG.............ddyfdaviasdietvakpspegkv 180
                 q++ va+       +  +a p   +p++++a+++Lk+ g+++v +++ ++      +a  lG             d +fdav+++ + +  kp+ + ++
  EEA20490.1 101 QAEGVAFA------DSIAAWP--AFPDTVDAMRKLKRLGFKLVPVSNVDHGSFGkTLAGPLGdlkepltsgseplDPFFDAVYTAQDIGSYKPDLRNFE 191
                 66666666......5666667..***********************999988885555558888899999999988899******************** PP

                 HHHHHHT....STGGGEEEE CS
                 xxxxxxx....xxxxxxxxx RF
   Hydrolase 181 aaireLq....gkpeevamV 196
                 ++i   +    ++++e+++V
  EEA20490.1 192 YLISHVKadfgVEKHEILHV 211
                 **999976666777777766 PP

>> HAD_2  Haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    3.7   0.0    0.0095        56       3      28 ..      16      51 ..      14     150 .. 0.58
   2 !   14.8   0.0   3.8e-06     0.022     119     178 .]     168     232 ..     163     232 .. 0.90

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.0095
       HAD_2  3 FDlDgTlldteeliiqafnelleey..........g 28
                FD+ gTl+d e+ i+qa+  + ++           +
  EEA20490.1 16 FDIYGTLIDWEKGILQALSPIRDRLpdssplksteN 51
                888899999999999988877766644444444440 PP

  == domain 2  score: 14.8 bits;  conditional E-value: 3.8e-06
       HAD_2 119 esyFdvivtsedvekkKPdpeviekalekl....klkkeeviyvGDsp.tDieaakkagikviav 178
                 + +Fd ++t++d++  KPd + +e ++ +     +++k+e++ v  s  +D   +k++g++++++
  EEA20490.1 168 DPFFDAVYTAQDIGSYKPDLRNFEYLISHVkadfGVEKHEILHVAQSLrHDHVPSKQIGLDSVWI 232
                 679****************9999888887666669*************9************9996 PP

>> CsbD  CsbD-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.1   0.00015      0.87      14      33 ..      87     106 ..      86     107 .. 0.93
   2 ?    1.5   0.2     0.048   2.9e+02       4      22 ..     236     254 ..     234     274 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00015
        CsbD  14 vKeaaGkaTgdekleaeGka 33 
                 +Ke +G   gd++l+aeG a
  EEA20490.1  87 AKELLGNGLGDDQLQAEGVA 106
                 79****************65 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.048
        CsbD   4 kgkaeqvkGkvKeaaGkaT 22 
                 +g +  + G vKe  G ++
  EEA20490.1 236 EGGVSGMGGDVKELMGQVA 254
                 5667778999999999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       231  (0.0128842); expected 358.6 (0.02)
Passed bias filter:                      226  (0.0126053); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 1925.26
//
Query:       EEA20491.1  [L=213]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-80  268.0   2.0    4.9e-80  267.8   2.0    1.0  1  DUF4202   Domain of unknown function (DUF4202)


Domain annotation for each model (and alignments):
>> DUF4202  Domain of unknown function (DUF4202)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  267.8   2.0   2.7e-84   4.9e-80       1     186 []       6     207 ..       6     207 .. 0.94

  Alignments for each domain:
  == domain 1  score: 267.8 bits;  conditional E-value: 2.7e-84
     DUF4202   1 ekalaaideahaeDPnkeeaeekes.....kpkellyaqkmtewlaklepeasealrlAaraqhlrRwevpRssYpegragYlkWRtelkkrqAelaae 94 
                 ++al+aideah++DPn ++++e+++     +p+el+yaqkmt++l++++++ase lrlA+raqhlrRwevpRssYp+++agYl+WRt lk+rqAe+a++
  EEA20491.1   6 QRALSAIDEAHSQDPNLTTITEQNEsetksIPYELHYAQKMTSYLESYNSSASEPLRLAIRAQHLRRWEVPRSSYPATKAGYLNWRTFLKNRQAEQARQ 104
                 68*************9988844433345559******************************************************************** PP

     DUF4202  95 lleeagydeeeiervaalvrkeelkr.............deetqlLEDvacLvFLedqfeeFakkheedeeklvdilrkTwaKmseegrelalklelse 180
                 ++++agy+++e+ rvaalvrke+lkr             ++etq+LEDvacLvFL+dqf++F+k    deek+++ilrkTwaKmse+gr++al++++s+
  EEA20491.1 105 ICLDAGYSDDEAGRVAALVRKEGLKRktattagetaeteEDETQVLEDVACLVFLDDQFAAFEKGL--DEEKILGILRKTWAKMSEKGRRMALEIQMSD 201
                 *************************8788888888888899**********************888..******************************* PP

     DUF4202 181 elkelv 186
                 +++elv
  EEA20491.1 202 RCRELV 207
                 ****98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (213 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       602  (0.0335769); expected 358.6 (0.02)
Passed bias filter:                      367  (0.0204696); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 1443.65
//
Query:       EEA20492.1  [L=328]
Description: calcium transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.7e-59  201.3   4.4    2.1e-59  201.0   4.4    1.1  1  VIT1          VIT family
  ------ inclusion threshold ------
       0.12   12.3   0.1       0.33   10.9   0.1    1.7  1  SLATT_fungal  SMODS and SLOG-associating 2TM effector domain


Domain annotation for each model (and alignments):
>> VIT1  VIT family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  201.0   4.4   2.4e-63   2.1e-59       1     215 []     103     320 ..     103     320 .. 0.92

  Alignments for each domain:
  == domain 1  score: 201.0 bits;  conditional E-value: 2.4e-63
        VIT1   1 lrdavlGanDGLvspfalvaGlsaaslgssktvllaGlaellAGaiSMgiGeYlsvkserdlekaerkreeeeleedpeegeaeelaeilearglseel 99 
                 ++da+lG++DGL++pfal aGls  ++g++k+v+l+Glael+AGaiSMg+G+Y+ +kse ++++a++++  +++  dp e+ +  +++ +++++ls+++
  EEA20492.1 103 ISDAILGLSDGLTVPFALSAGLS--AIGDTKVVVLGGLAELIAGAISMGLGGYVGAKSELESYEATVRE-VDAILYDPGET-QSMITSTFAKYNLSPST 197
                 589********************..6679************************************9877.88888888444.3778************* PP

        VIT1 100 aqevaaellknpdallelmlreelg...psaseelasplkaAlssalsfliGgliPllpylfvesvglalvvsiavtllalllfGavkallt....... 188
                  +e+++ l+++p++l++++l++++    p+     +++  +Al+  l+++iGg+iPl+py+++++v +a+++s++v++++l++fG++k++++       
  EEA20492.1 198 LDEITKSLQAEPERLRDFLLNFHYResePDC----NQASMSALTLTLGYFIGGFIPLIPYFIADQVYTAFIASVIVMAVTLFAFGYIKTCIVrgwqggv 292
                 *********************9886322443....45667*********************************************************99 PP

        VIT1 189 gssk.lvsalrmlliGalAaaaayligk 215
                 + +  ++++++m ++G+lAa+aa++++k
  EEA20492.1 293 NIWAgVIGGIQMCVVGGLAAGAAVALVK 320
                 77888********************985 PP

>> SLATT_fungal  SMODS and SLOG-associating 2TM effector domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.1   3.7e-05      0.33      32      99 ..     119     180 ..     114     213 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 3.7e-05
  SLATT_fungal  32 AlltaLgalssgrtqvaitvLGalnTviAglLArlrgsgePersrkrrkdlekvireieafeldagea 99 
                   Al ++L+a+ +++    ++vLG+l+ +iAg + +  g g    ++++ + +e  +re++a ++d ge+
    EEA20492.1 119 ALSAGLSAIGDTK----VVVLGGLAELIAGAISM--GLGGYVGAKSELESYEATVREVDAILYDPGET 180
                   8889999996655....9************7765..77777778888888888888888888887753 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (328 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       875  (0.0488036); expected 358.6 (0.02)
Passed bias filter:                      552  (0.0307881); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.31s 00:00:00.85 Elapsed: 00:00:00.48
# Mc/sec: 2054.46
//
Query:       EEA20493.1  [L=604]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.5e-09   36.4   0.0    3.7e-09   35.9   0.0    1.2  1  Fungal_trans_2  Fungal specific transcription factor domain
     0.0013   18.8   4.5     0.0045   17.1   4.5    1.9  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.9   0.0   4.2e-13   3.7e-09       3     165 ..     187     344 ..     186     406 .. 0.85

  Alignments for each domain:
  == domain 1  score: 35.9 bits;  conditional E-value: 4.2e-13
  Fungal_trans_2   3 ldyyldnvapllspvpessnpfrkvllplalsnkallhallalsafhlqskgpkdslereakrykslalkelqealaelsstls..rnekykdiL 95 
                     ++++++n++  +s+++ + + +++++ +  + +++l ha++a++a+h+ +  +++   +++   +s a+++ ++a+ +l+++l   ++++++  L
      EEA20493.1 187 FEFFIRNTSSQCSVFYGH-DFWQRIVPQYTEVEPGLRHAVIAVGALHR-NFEQSQ--LNSQDPDYSFAIQQCNRAIYNLQHRLVgdKSRHMEVAL 277
                     579**************8.9****************************.666666..55666666779*****************999999**** PP

  Fungal_trans_2  96 aaiLllcsieissgdvsdwrvhLeaatsliksrggskasssslsskarfllrifayldilssttlgrgps 165
                     ++++l +s+   +gd +     +++  +l+  + +  +ss ++s     l+r f+ +   + t+ +  p 
      EEA20493.1 278 ITCILFVSFAFLQGDAGAASRLMHGGVKLLLEWEKI-SSSLDDSTIKLALMRVFSRIQFHAMTCGD--PD 344
                     ************************************.66666666666788888888877776666..44 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   4.5     5e-07    0.0045       7      39 ..      40      72 ..      40      73 .. 0.92

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 5e-07
                HHCT---STSSSS-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus  7 rkkKvKCdakkPaCsnCkklnleCtfysesskr 39
                r ++ KCd+ +P+C  C + + +C  y++  +r
  EEA20493.1 40 RIRHKKCDETQPSCYMCTSTGRTCDGYRQTPDR 72
                789**********************99998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (604 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       471  (0.0262703); expected 358.6 (0.02)
Passed bias filter:                      375  (0.0209158); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.24s 00:00:00.82 Elapsed: 00:00:00.42
# Mc/sec: 4344.03
//
Query:       EEA20494.1  [L=117]
Description: hypothetical protein PMAA_043310 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.042   13.0   0.0      0.052   12.7   0.0    1.1  1  ECSIT     Evolutionarily conserved signalling intermediate in


Domain annotation for each model (and alignments):
>> ECSIT  Evolutionarily conserved signalling intermediate in Toll pathway
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   2.9e-06     0.052       5      85 ..      17      97 ..       9     100 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.9e-06
       ECSIT  5 kseskpkeeeraeeekkkekkalvlreelfekaagekkdkatfleavevfekrsvrrrghveFiyaAlkkmeefgverDle 85
                +s+s+  ++++  + ++++++   +   + ++++++ +++ +f +a   +++r++ +r+      +  ++m+ f +e+Dl 
  EEA20494.1 17 SSKSSSPKNNMNMDLSQSQSSLPLAIPPVVNNISNKLRNRLSFKSARAAYAEREILKRENRAARPLTQRNMDTFLIEQDLR 97
                2333333333444445555555577888999*****************************99999**************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (117 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       854  (0.0476323); expected 358.6 (0.02)
Passed bias filter:                      341  (0.0190195); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.25s 00:00:00.63 Elapsed: 00:00:00.40
# Mc/sec: 884.08
//
Query:       EEA20495.1  [L=202]
Description: hypothetical protein PMAA_043320 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.5e-05   22.6   0.4     0.0002   20.1   0.4    1.9  1  AA_permease  Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   0.4   1.1e-08    0.0002     317     402 ..      92     195 ..      91     198 .. 0.90

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 1.1e-08
  AA_permease 317 slakdglaPkvlkkvskrgvPlraillsmiisllal...............llaslnlaap...ivfnfllaisaliglivwlliilsylrfRkalky 396
                  +la++g aP ++ +++k+gvP+  +++   + ++                 ll+++++ ++   +    +l +++++ l+ w++i++s++rfR+ l++
   EEA20495.1  92 ALAQQGQAPNFVLRCTKQGVPIYCVVMGHRAEYIDSnpdfpprvaitgpvgLLTYMTVCLFrrrSDLSLVLQLTTIVYLLPWTCICYSHIRFRRGLSA 189
                  89***************************99999999**************8888887654111668899*************************999 PP

  AA_permease 397 qgrsie 402
                   ++ i+
   EEA20495.1 190 ANIGIN 195
                  988776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (202 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       388  (0.0216409); expected 358.6 (0.02)
Passed bias filter:                      309  (0.0172346); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.32s 00:00:00.74 Elapsed: 00:00:00.46
# Mc/sec: 1332.13
//
Query:       EEA20496.1  [L=750]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.8e-16   57.4   0.0    7.6e-13   47.7   0.0    2.1  2  FMO-like       Flavin-binding monooxygenase-like
    2.5e-10   40.1   0.0    4.9e-08   32.6   0.0    3.0  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    5.8e-08   32.3   0.1    0.00058   19.2   0.0    3.3  3  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
    1.1e-07   31.9   0.0    4.6e-07   29.9   0.0    2.1  2  NAD_binding_9  FAD-NAD(P)-binding
    4.2e-07   29.4   0.0    6.9e-05   22.1   0.0    2.9  3  K_oxygenase    L-lysine 6-monooxygenase (NADPH-requiring)
    6.6e-05   23.1   0.0    0.00079   19.6   0.0    2.6  2  NAD_binding_8  NAD(P)-binding Rossmann-like domain
  ------ inclusion threshold ------
      0.014   15.9   0.0        8.5    7.0   0.0    2.7  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
      0.074   12.3   0.3       0.27   10.4   0.0    2.1  2  FAD_binding_3  FAD binding domain
       0.21   10.8   0.3       0.54    9.5   0.0    1.7  2  Thi4           Thi4 family


Domain annotation for each model (and alignments):
>> FMO-like  Flavin-binding monooxygenase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.7   0.0   3.8e-16   7.6e-13       2     203 ..       5     239 ..       4     262 .. 0.72
   2 !    7.6   0.0   0.00055       1.1     314     396 ..     392     480 ..     365     523 .. 0.72

  Alignments for each domain:
  == domain 1  score: 47.7 bits;  conditional E-value: 3.8e-16
    FMO-like   2 kkvaviGaGvsGlasikcclee....gleptcfersddiGGlwrfke......nveeGrasiyks.vvsnsskemscfsdfplpedyp.n.......fl 81 
                 kkva+iGaG sGl+  k+ l++     +ep+ f+    +GG+w  +       + + G +      + +n s+  + fsd+  +e+   n       f 
  EEA20496.1   5 KKVAIIGAGPSGLVMAKTLLHNypkgYFEPIVFDSKPTVGGIWAVTRpdgsstSKNLGPSDFVDCfMRTNLSRFTVSFSDHSWNEENQsNegneedmFP 103
                 9*****************9986333258***************9975211111223354554444145899***********98865413222333355 PP

    FMO-like  82 hnsklleylklfakefdllkyiqfkttvcsvkkrp.d...fstsGqwevv.t...eke.gkkesavfdavmvctGhhvnphlplesfpGiekf.kGqyf 170
                 +  k+ eylk +a++f     +++ + v s +++  d       G+w v  t   +++ +k+ s+ fd ++v +G++  p++p  s  G+++f k +++
  EEA20496.1 104 QAWKVGEYLKSYANRFLPREALRLSSRVRSTRRNQnDndnTPMMGKWTVEwTdqrHTDgEKHLSESFDYLVVASGYFSRPYIP--SITGLDEFpKDRII 200
                 666899**********9999999999998887643131114567***995221112332577799*****************9..899****98999** PP

    FMO-like 171 hsrdykepevf......kgkrvlviGlGnsggdiavels 203
                 hs   ++ +        ++ ++lv+G   sg++ a+ ++
  EEA20496.1 201 HSSSLRSNSQIldslgeDDGKILVVGGSMSGAEAATSIA 239
                 **9988765432222335679****98888877665543 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.00055
    FMO-like 314 dgtveedidvvifatGyt.f.afpfleeslvkveknkvslykkvfpanle.....kptlaiiGliqp.lGsilptvelqarwavrvlkGlk 396
                 ++ + +++ ++ifatG+t f +  fl + +++  +   +   +vfp  l+     +p +  +G++   +G    + e+qar  +r   G  
  EEA20496.1 392 NTVKLDNVAAIIFATGFTpFeSLFFLPDDVLRTLE--YTENDTVFPIVLDeksvrNPDIPDLGFVGMyRGPYWGVMEMQARSLARQWSGHI 480
                 567889***********966356678777665543..344566777666411111566778999986379999999999999988877755 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.6   0.0   2.5e-11   4.9e-08       1     161 [.       5     238 ..       5     263 .. 0.69
   2 ?    1.7   0.0      0.06   1.2e+02      83     113 ..     382     412 ..     363     435 .. 0.60

  Alignments for each domain:
  == domain 1  score: 32.6 bits;  conditional E-value: 2.5e-11
                  CSEEEE--SHHHHHHHHHHHH....HTS-EEEEE....TTHCHHHCSHHHHCHHHHHHHHHHHHH................................. CS
                  xxxxxxxxxxxxxxxxxxxxx....xxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxx................................. RF
  Pyr_redox_2   1 kdvvviGgGpAGlaaaltlaq....agakvtlve....legtclnggcllskallgvaedaeias................................. 57 
                  k+v++iG+Gp Gl +a+tl +      ++ ++++           gg++  +   g++  ++                                    
   EEA20496.1   5 KKVAIIGAGPSGLVMAKTLLHnypkGYFEPIVFDskptV------GGIWAVTRPDGSSTSKNLGPsdfvdcfmrtnlsrftvsfsdhswneenqsneg 96 
                  58*******************777436677777433331......22333233333333333222455556666677777899999999999999999 PP

                  ...................................HHHHCHHHHCCCCHCCTCEEEEESCEEEEETEEEC...TCEEEEEESEEEE---..EEE-BCT CS
                  ...................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxx..xxxxxxx RF
  Pyr_redox_2  58 ...................................evvkklnqgielllgeevvkidpgkkkvklekkke...gdeekiaydklvlAtG..ssprdlg 115
                                                     +      +  ++ +++  + + +gk +v+ ++++    +++ +  +d+lv+A+G  s+p ++ 
   EEA20496.1  97 needmfpqawkvgeylksyanrflprealrlssrvR------STRRNQNDNDNTPM-MGKWTVEWTDQRHtdgEKHLSESFDYLVVASGyfSRPYIPS 187
                  9*****999999988888888888876653332221......22222222223333.233344444443354456666778********877****** PP

                  CTTC.....TTBEECCSECHHHHHHCCSS-T..SEEEEES-SHHHHHHHHHH CS
                  xxxx....xxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 116 ipGv....aenvgklvrtldsaealklkllp..krivvvGgGyiGvElAaal 161
                  i G+    ++  +++ ++l+s  ++ + l +   +i+vvGg++ G E A  +
   EEA20496.1 188 ITGLdefpKDRIIHS-SSLRSNSQILDSLGEddGKILVVGGSMSGAEAATSI 238
                  ****88877777777.888888888888888999**************9874 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.06
                  EEEEETEEECTCEEEEEE.SEEEE---EEE-B CS
                  xxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxx RF
  Pyr_redox_2  83 kkvklekkkegdeekiay.dklvlAtGssprd 113
                  + v++ ++++g++ k++   +++ AtG++p+ 
   EEA20496.1 382 GVVEI-EQNDGNTVKLDNvAAIIFATGFTPFE 412
                  22333.22223333332235667777777764 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.8   0.1    0.0035         7       2      16 ..       9      23 ..       8      31 .. 0.87
   2 !   19.2   0.0   2.9e-07   0.00058     126     183 ..     171     238 ..     160     255 .. 0.81
   3 ?    3.2   0.0     0.021        42     240     270 ..     379     411 ..     363     433 .. 0.77

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0035
  Pyr_redox_3  2 IiGaGPaGlaaaiel 16
                 IiGaGP Gl +a +l
   EEA20496.1  9 IIGAGPSGLVMAKTL 23
                 9**********9876 PP

  == domain 2  score: 19.2 bits;  conditional E-value: 2.9e-07
  Pyr_redox_3 126 kkviiAtGefdkPnklnipGeek....lvkhyskvkefhky......agqkvvViGgknSavDaAlel 183
                  +++++A G+f++P+ ++i G ++      +h+s  ++ +++       + k++V+Gg+ S+++aA+ +
   EEA20496.1 171 DYLVVASGYFSRPYIPSITGLDEfpkdRIIHSSSLRSNSQIldslgeDDGKILVVGGSMSGAEAATSI 238
                  689*****************9863323456888887766653333335789**************976 PP

  == domain 3  score: 3.2 bits;  conditional E-value: 0.021
  Pyr_redox_3 240 ekeeeykvktedgkkvevkd..dvvlatGykpd 270
                  e++  ++++++dg++v+ ++   +++atG++p 
   EEA20496.1 379 ETKGVVEIEQNDGNTVKLDNvaAIIFATGFTPF 411
                  566778999999999999662268999***985 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.9   0.0   2.3e-10   4.6e-07       1     143 [.       8     159 ..       8     180 .. 0.66
   2 ?   -1.9   0.0       1.5     3e+03     128     150 ..     377     400 ..     367     408 .. 0.66

  Alignments for each domain:
  == domain 1  score: 29.9 bits;  conditional E-value: 2.3e-10
  NAD_binding_9   1 aivGaGprGlavlerLlarakkkspleitlfdpsepgagrvwrtdq...seelllNvpasemslftddp.......ptfaeWlrergaleeaeeld 86 
                    ai+GaGp+Gl +++ Ll++  +k  +e  +fd +++  g++w  ++   s++     p++ +  f   +        + + W +e++     e+ +
     EEA20496.1   8 AIIGAGPSGLVMAKTLLHNY-PKGYFEPIVFDSKPTV-GGIWAVTRpdgSSTSKNLGPSDFVDCFMRTNlsrftvsFSDHSWNEENQS---NEGNE 98 
                    8******************6.999************8.88887665211444444469999999998778888844333456555553...46788 PP

  NAD_binding_9  87 pddfvpRalyGrYlrdlfeellarl..pegvtvevhraevvdleera..dgqavlladgas 143
                    +d f++   +G+Yl+++++++l r   + + +v+  r +  d ++++  ++++v ++d+++
     EEA20496.1  99 EDMFPQAWKVGEYLKSYANRFLPREalRLSSRVRSTRRNQNDNDNTPmmGKWTVEWTDQRH 159
                    999999999***********99654123333444444444433333332446666665554 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 1.5
  NAD_binding_9 128 eeradgq.avlladgaslaadaVv 150
                    e + +g+ ++ ++dg+++++d+V 
     EEA20496.1 377 EAETKGVvEIEQNDGNTVKLDNVA 400
                    444555448889999999988873 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0     0.019        38     191     216 ..       4      29 ..       1      48 [. 0.65
   2 !   22.1   0.0   3.5e-08   6.9e-05      99     212 ..     109     240 ..      71     264 .. 0.73
   3 ?   -0.4   0.0      0.25   4.9e+02     311     341 ..     379     409 ..     364     410 .. 0.67

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.019
  K_oxygenase 191 kkriaVvGsGqSaaeifedllrrqkk 216
                   k++a++G+G S+  +++ ll++++k
   EEA20496.1   4 TKKVAIIGAGPSGLVMAKTLLHNYPK 29 
                  56677777777766666666665543 PP

  == domain 2  score: 22.1 bits;  conditional E-value: 3.5e-08
  K_oxygenase  99 edYlrWvasqle..eqvrfgeeveevepdeeeee.....elltveskd.aegeeeelea...rnlvlgvG..tepkiPev..leklegkervvHssey 181
                   +Yl+  a+++   e +r +++v++ + ++++++       +tve +d ++ + e++ +     lv++ G  ++p+iP++  l+++  k+r++Hss++
   EEA20496.1 109 GEYLKSYANRFLprEALRLSSRVRSTRRNQNDNDntpmmGKWTVEWTDqRHTDGEKHLSesfDYLVVASGyfSRPYIPSItgLDEFP-KDRIIHSSSL 205
                  57787777777534668889999998888865443433334788877654444444444112569*****999*****993345555.7*******99 PP

  K_oxygenase 182 lerkee....llakkriaVvGsGqSaaeifedllr 212
                   ++ +      ++  +i+VvG+  S+ae +  ++ 
   EEA20496.1 206 RSNSQIldslGEDDGKILVVGGSMSGAEAATSIAL 240
                  998855888788999*************8766554 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 0.25
  K_oxygenase 311 kgeveltlrneesgeeetlevdavvlATGYr 341
                  +++  +++++++ ++ +  +v a+++ATG++
   EEA20496.1 379 ETKGVVEIEQNDGNTVKLDNVAAIIFATGFT 409
                  234556777777788888889999*****96 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.0     4e-07   0.00079       1      52 [.       9      66 ..       9      79 .. 0.76
   2 ?   -0.1   0.0      0.54   1.1e+03       1      16 [.     224     239 ..     224     251 .. 0.85

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 4e-07
                   EE--SHHHHHHHHHHHCC...TE.EEEEE-SSSSSSGGG-EECETT..CEECTS---E CS
  NAD_binding_8  1 IvGaGlsGlvaAylLaka...gf.dvlllekrdrlGGraasyevpg..vrvdygahif 52
                   I+GaG sGlv+A +L  +   g+ +  ++++ + +GG +a  + +g     ++g++ f
     EEA20496.1  9 IIGAGPSGLVMAKTLLHNypkGYfEPIVFDSKPTVGGIWAVTRPDGssTSKNLGPSDF 66
                   9***********997654477767*************888776666555555666655 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.54
                    EE--SHHHHHHHHHHH CS
  NAD_binding_8   1 IvGaGlsGlvaAylLa 16 
                    +vG+ +sG+ aA  +a
     EEA20496.1 224 VVGGSMSGAEAATSIA 239
                    8*******99997665 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.0    0.0043       8.5       1      18 [.       6      23 ..       6      31 .. 0.90
   2 ?    6.0   0.0    0.0091        18       1      18 [.     221     238 ..     221     257 .. 0.89

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0043
                EEEEECSSHHHHHHHHHH CS
   Pyr_redox  1 kvvvvGgGyiglElAgal 18
                kv+++G+G +gl +A++l
  EEA20496.1  6 KVAIIGAGPSGLVMAKTL 23
                79*************998 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.0091
                 EEEEECSSHHHHHHHHHH CS
   Pyr_redox   1 kvvvvGgGyiglElAgal 18 
                 k++vvGg+ +g E+A+ +
  EEA20496.1 221 KILVVGGSMSGAEAATSI 238
                 79*************875 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   0.00014      0.27       3      21 ..       6      24 ..       4      27 .. 0.87
   2 ?   -1.8   0.1      0.74   1.5e+03      89     152 ..     601     665 ..     557     673 .. 0.65

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00014
                   EEEEE--SHHHHHHHHHHH CS
  FAD_binding_3  3 dVlIVGaGpaGlmlallLs 21
                   +V+I+GaGp+Gl+ a+ L 
     EEA20496.1  6 KVAIIGAGPSGLVMAKTLL 24
                   79***********999875 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.74
                    EHHCHHCST-CEE--HHHHHHHHHHHHHHHTEEETCSEE..EECCEECCCCCCCEEEECCTTEEEE CS
  FAD_binding_3  89 dlelesspervtvypqteleriLvehaeerglqvrfkte..vesleqdeegvtaevrdketgeeet 152
                    ++e e  pe++t+ +q  +    ++  e +g++++f  e    +++qd+ +vt ++ + e+g ++t
     EEA20496.1 601 RYEREILPETTTMTGQASIHLQKASYNEDAGFTTEFVYEedSSTMQQDDPQVTFRISE-EDGGIYT 665
                    4555566777777777776666666667778777777773345555555555555544.4666666 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.0   0.00027      0.54      19      58 ..       6      47 ..       2      50 .. 0.76
   2 ?   -2.2   0.1      0.96   1.9e+03      19      37 ..     221     239 ..     206     243 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00027
                EEEEE--SHHHHHHHHHHHHC.TT..S-EEEEESSSS--TTTT CS
        Thi4 19 DvvivGaGssGLtaayylakk.pd..lkvailersvspGGGaw 58
                 v+i+GaG+sGL  a++l ++ p+  ++ ++++++ ++G G+w
  EEA20496.1  6 KVAIIGAGPSGLVMAKTLLHNyPKgyFEPIVFDSKPTVG-GIW 47
                699*************99998764336677777776665.455 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.96
                 EEEEE--SHHHHHHHHHHH CS
        Thi4  19 DvvivGaGssGLtaayyla 37 
                  +++vG+  sG  aa  +a
  EEA20496.1 221 KILVVGGSMSGAEAATSIA 239
                 4899***********9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (750 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       553  (0.0308439); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.80u 0.35s 00:00:01.14 Elapsed: 00:00:00.56
# Mc/sec: 4066.48
//
Query:       EEA20497.1  [L=304]
Description: COPII-coated vesicle protein SurF4/Erv29, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.5e-96  323.1   8.0    1.7e-96  322.9   8.0    1.0  1  SURF4           SURF4 family
  ------ inclusion threshold ------
        9.2    6.2   8.3       0.27   11.1   0.8    2.2  3  UPF0139         Uncharacterised protein family (UPF0139)


Domain annotation for each model (and alignments):
>> SURF4  SURF4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  322.9   8.0  1.9e-100   1.7e-96       3     267 .]      40     304 .]      38     304 .] 0.98

  Alignments for each domain:
  == domain 1  score: 322.9 bits;  conditional E-value: 1.9e-100
       SURF4   3 liakiedlaetllrktkkylPtlarlllvatfleDglrllfqwsdqveyldkskklgyflatllvlvvllglligsllvvlrkkvayavgvLlfivilq 101
                   +kied  +tl   +k+y+P ++r+l+v tfleD+lr+++qw dq  +l++++++++ ++ l++++++l +l +s++v++r++ +yavg Ll +v++q
  EEA20497.1  40 QTSKIEDWLDTLSDPIKPYIPAIGRFLIVVTFLEDSLRIVTQWGDQLMFLRDYRHIPWGITHLFLILNVLVMLSASVMVIARRHSEYAVGGLLGVVVTQ 138
                 6799*********************************************************************************************** PP

       SURF4 102 aiaYslltdlklllrnlsvigglllllaesliekkslfaglPeleeeekaksylllagrvllvlmfisllaf.elsftrvlltiigvaliilvviGfkt 199
                 a+ Y+ll d++++lrnlsvigglll++++s ++kk + aglP+l+e ++ k y++lagrvll+l+fi+++   +  f+rvl+++ig++++++vv+Gfk+
  EEA20497.1 139 ALGYGLLFDINFFLRNLSVIGGLLLVISDSWVRKKYMPAGLPQLDE-KDRKMYVQLAGRVLLILLFIGFILAgKWTFWRVLVSLIGFVACVMVVVGFKA 236
                 *********************************************9.899******************9865269************************ PP

       SURF4 200 klaalvLvllLfvlnlvlnafWtipkekelrdflkYdffqtlsviGGLLlvvatGpGelsvDekkkky 267
                 k++a++Lv+lL+v+n+++n+fWt+  +++ +df kYdffq ls++GGLLl+v++GpG++svDekkk y
  EEA20497.1 237 KMSAVILVILLSVFNVLVNNFWTLKPHHPNKDFAKYDFFQVLSIVGGLLLLVNMGPGQFSVDEKKKVY 304
                 ******************************************************************87 PP

>> UPF0139  Uncharacterised protein family (UPF0139)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.7   0.8         2   1.8e+04      77      86 ..     109     118 ..     106     120 .. 0.66
   2 ?   11.1   0.8     3e-05      0.27      16      90 ..     179     253 ..     166     263 .. 0.76
   3 ?   -0.4   0.0      0.12   1.1e+03      18      41 ..     262     285 ..     254     289 .. 0.76

  Alignments for each domain:
  == domain 1  score: -4.7 bits;  conditional E-value: 2
     UPF0139  77 sfmlsvsalv 86 
                  +mls s +v
  EEA20497.1 109 LVMLSASVMV 118
                 4677777776 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 3e-05
     UPF0139  16 ppalssqkedltpdymnllgmifsllglmlklkwcaWvalvcslisfanskssddlkqilssfmlsvsalvmsYl 90 
                  p+l++++  ++++ ++ + +i+ ++g++l  kw+ W  lv  +  +a + +  + k+ +s+++l +   v + l
  EEA20497.1 179 LPQLDEKDRKMYVQLAGRVLLILLFIGFILAGKWTFWRVLVSLIGFVACVMVVVGFKAKMSAVILVILLSVFNVL 253
                 3455555566777777778899****************9999999999999999999999999877665554444 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 0.12
     UPF0139  18 alssqkedltpdymnllgmifsll 41 
                  ++++k+ ++ d++++l+++ +ll
  EEA20497.1 262 PHHPNKDFAKYDFFQVLSIVGGLL 285
                 45566778899*******998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (304 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1005  (0.0560544); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.72u 0.36s 00:00:01.08 Elapsed: 00:00:00.58
# Mc/sec: 1567.38
//
Query:       EEA20498.1  [L=310]
Description: lactonase drp35, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.3e-39  134.6   0.0    5.3e-39  134.3   0.0    1.1  1  SGL           SMP-30/Gluconolactonase/LRE-like region
    4.2e-06   26.5   7.4       0.04   14.0   0.0    5.6  7  NHL           NHL repeat
    4.6e-05   23.5   0.0       0.07   13.3   0.0    3.4  2  Str_synth     Strictosidine synthase
  ------ inclusion threshold ------
      0.019   15.1   0.0       0.21   11.8   0.0    2.6  3  Arylesterase  Arylesterase


Domain annotation for each model (and alignments):
>> SGL  SMP-30/Gluconolactonase/LRE-like region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  134.3   0.0   1.2e-42   5.3e-39       3     244 ..      45     282 ..      43     284 .. 0.94

  Alignments for each domain:
  == domain 1  score: 134.3 bits;  conditional E-value: 1.2e-42
         SGL   3 EGpvwdeeegaLlwvDilgqrihrldpatgketvldtpe.svGaiaprkdgrlvvasksglalldlasgeletladeeedekpllrfNDgvvdpdGrlw 100
                 EGp  d   g ++ vDi+ +ri+r+ p+++ + ++++++ ++G+ +   dgr++va +++ ++  ++sg+  +l++   +e +   +ND+ + p+G ++
  EEA20498.1  45 EGPCFDS-AGNIYVVDIPFGRIFRIAPDKTWSLFAEYDGwPNGLKIT-SDGRILVADHRQGLVEITDSGKALVLVSGYRGE-RFRGLNDLTIGPNGWIY 140
                 9999995.99*************************************.9*******999888876799**99***998888.***************** PP

         SGL 101 fGtmgdeeakgeevgalyrldpd.gklervlddltipNGlawspdgktlYlaDsltrkiwaydvdaeggklsnrrvfadlkkgegepDGlavDaeGnvw 198
                 f++ g +  ++  +g +yr++ + + lervl+++  pNGl +s d++ l++a ++++ iw++++  +gg +s+  vf++l+ g+g pDGlavDaeG+++
  EEA20498.1 141 FTDQGQSGLQEP-GGYVYRYHLNsKILERVLSNIPSPNGLVLSIDTTRLFVAVTRANAIWRVPFVLDGG-VSKVGVFLNLSGGGG-PDGLAVDAEGGLI 236
                 *****9998888.7*********788*******************************************.*************87.************* PP

         SGL 199 vAvwgggkvvrfdpdGklieeiklpak.rvtscaFgGpdlrtLyits 244
                 vA+  g +v rfd +G l++ ++lp +  ++++aF   ++++++it 
  EEA20498.1 237 VAQP-GLGVLRFDAAGVLTHFVQLPRNsAPSNIAFDPHERHRMVITD 282
                 **77.779*****************666*******88999*****95 PP

>> NHL  NHL repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.0   0.0    0.0063        28       8      19 ..      48      59 ..      45      64 .. 0.88
   2 !   14.0   0.0   8.9e-06      0.04       3      20 ..      83     100 ..      82     107 .. 0.90
   3 ?   -2.0   0.0         1   4.5e+03       1      16 [.     125     140 ..     125     144 .. 0.78
   4 ?   -0.5   0.0      0.33   1.5e+03       3      18 ..     175     191 ..     174     199 .. 0.81
   5 ?   -1.9   0.0      0.99   4.4e+03      16      28 .]     203     215 ..     203     215 .. 0.88
   6 !    6.6   0.1     0.002       8.8       3      18 ..     223     238 ..     222     238 .. 0.89
   7 ?   -2.3   0.0       1.2   5.6e+03      20      27 ..     273     280 ..     271     285 .. 0.66

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0063
                EEETTTEEEEEE CS
         NHL  8 avdsnGdiyVaD 19
                + ds G+iyV D
  EEA20498.1 48 CFDSAGNIYVVD 59
                889********9 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 8.9e-06
                 SEEEEEEETTTEEEEEEC CS
         NHL   3 yPhGvavdsnGdiyVaDs 20 
                 +P+G+ ++s+G+i+VaD 
  EEA20498.1  83 WPNGLKITSDGRILVADH 100
                 6****************6 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 1
                 BSSEEEEEEETTTEEE CS
         NHL   1 fnyPhGvavdsnGdiy 16 
                 f+  +++++ +nG iy
  EEA20498.1 125 FRGLNDLTIGPNGWIY 140
                 5667899999999776 PP

  == domain 4  score: -0.5 bits;  conditional E-value: 0.33
                 SEEEEEEE.TTTEEEEE CS
         NHL   3 yPhGvavd.snGdiyVa 18 
                 +P+G++++ ++ +++Va
  EEA20498.1 175 SPNGLVLSiDTTRLFVA 191
                 59999998888777776 PP

  == domain 5  score: -1.9 bits;  conditional E-value: 0.99
                 EEEECCCTEEEEE CS
         NHL  16 yVaDsenhrvqvF 28 
                 +V D + + v vF
  EEA20498.1 203 FVLDGGVSKVGVF 215
                 5899999999999 PP

  == domain 6  score: 6.6 bits;  conditional E-value: 0.002
                 SEEEEEEETTTEEEEE CS
         NHL   3 yPhGvavdsnGdiyVa 18 
                  P G+avd  G ++Va
  EEA20498.1 223 GPDGLAVDAEGGLIVA 238
                 699*****99999997 PP

  == domain 7  score: -2.3 bits;  conditional E-value: 1.2
                 CCCTEEEE CS
         NHL  20 senhrvqv 27 
                  e+hr+++
  EEA20498.1 273 HERHRMVI 280
                 56777654 PP

>> Str_synth  Strictosidine synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0     0.012        54      35      72 ..      61      97 ..      55     105 .. 0.80
   2 !   13.3   0.0   1.6e-05      0.07       2      81 ..     130     198 ..     129     201 .. 0.79

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.012
   Str_synth 35 ktGrllkydkstkvvkvlldkLyfanGialsedgsfvl 72
                ++Gr+++  + +      ++    +nG+++++dg  ++
  EEA20498.1 61 PFGRIFRIAPDKTWS-LFAEYDGWPNGLKITSDGRILV 97
                578888888876655.66777778**********9876 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 1.6e-05
   Str_synth   2 aldvdeetgvlyftdsSskydrrqvllallegdktGrllkydkstkvvkvlldkLyfanGialsedgsfvlvcetamkri 81 
                 +l++ ++ g +yftd  +             +++ G +++y  + k    +l+++  +nG+ ls d + + v+ t  + i
  EEA20498.1 130 DLTIGPN-GWIYFTDQGQ----------SGLQEPGGYVYRYHLNSKILERVLSNIPSPNGLVLSIDTTRLFVAVTRANAI 198
                 5566666.6666666543..........3578999*********************************999887766655 PP

>> Arylesterase  Arylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0      0.95   4.3e+03      56      68 ..      84      96 ..      78     101 .. 0.84
   2 ?   11.8   0.0   4.6e-05      0.21      39      80 ..     156     200 ..     139     203 .. 0.81
   3 ?   -1.0   0.0      0.47   2.1e+03      53      62 ..     281     290 ..     257     292 .. 0.60

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.95
  Arylesterase 56 anGInidadkkyi 68
                  +nG++i +d +++
    EEA20498.1 84 PNGLKITSDGRIL 96
                  9********9976 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 4.6e-05
  Arylesterase  39 vY.y..spsevkvvasglssanGInidadkkyiyvadilresihv 80 
                   vY y  +++ ++ v s + s+nG++++ d   ++va   ++ i++
    EEA20498.1 156 VYrYhlNSKILERVLSNIPSPNGLVLSIDTTRLFVAVTRANAIWR 200
                   33231256678899**********************999999987 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 0.47
  Arylesterase  53 lssanGInid 62 
                    +sanGI ++
    EEA20498.1 281 TDSANGIIYE 290
                   4677887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (310 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       270  (0.0150594); expected 358.6 (0.02)
Passed bias filter:                      262  (0.0146132); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.64u 0.35s 00:00:00.99 Elapsed: 00:00:00.58
# Mc/sec: 1613.07
//
Query:       EEA20499.1  [L=495]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-29  103.3  25.6    1.6e-29  102.9  25.6    1.1  1  MFS_1     Major Facilitator Superfamily
    2.4e-18   66.2  19.1    3.4e-18   65.7  19.1    1.2  1  Sugar_tr  Sugar (and other) transporter
  ------ inclusion threshold ------
        1.3    8.6   3.9         22    4.6   0.1    3.6  3  DUF4131   Domain of unknown function (DUF4131)
          4    6.1   9.6       0.19   10.5   2.5    2.3  2  DUF2207   Predicted membrane protein (DUF2207)
        4.4    6.9  29.0        1.1    8.9   7.3    3.5  3  TauE      Sulfite exporter TauE/SafE


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.9  25.6   4.6e-33   1.6e-29       4     352 ..      64     426 ..      61     427 .. 0.88

  Alignments for each domain:
  == domain 1  score: 102.9 bits;  conditional E-value: 4.6e-33
       MFS_1   4 aaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgagal 102
                  ++ls+l+rs+lg a      +d g+ +  +g ++tl ++ ++++ +p+   + rfG+ r l ++lll++  +l+ +f+ ++   +++r+l G++++++
  EEA20499.1  64 FLVLSSLDRSNLGNARVFGFDQDIGLHGGMFGNITTLLSVSFIIFEVPWVLAVKRFGANRALGTALLLWSCVTLATAFVKTYGQAIAVRMLLGACEAGV 162
                 5678899999999999889999**************************************99999999999945555877777**************** PP

       MFS_1 103 fpagaaliadwfpkeergraigllsagfslGailgpllggllasslg.......Wravfyilaivsllafvlfllllpeepperkrkspkeee...... 188
                  p+ a+l+a ++p++  g+ + + ++++  + ++g l++ ++  + g       Wr++f++   v+++++ ++++ lp +p + +  s++e+e      
  EEA20499.1 163 SPSFAYLFATIYPQRLAGKRVMMTNLANCTSGAFGGLFAYAVQ-QMGerrgiaaWRWLFIVEFCVTFVVGGIGWCILPHSPETAWFLSEEEKEtmrlrk 260
                 **************99999999999999999999988877766.5556***********************999*************999999999766 PP

       MFS_1 189 ...kgtgpaplvp........awkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrr 276
                    +                  +k+ lkdp+++++ ia+++ +++++g+ ++lp++    lg++ +l + ++   +++vgai+ + + ++sd+++r  r
  EEA20499.1 261 krdETF------RgkdildkkWIKMSLKDPFIYVCGIAFFTSSVAITGFGVFLPTI-IAGLGFA-ALKVNYMTIPVYVVGAISLVTCCYFSDKFNR--R 349
                 555222......223333465577888888888999*******************7.*******.7888889999999999999*********999..9 PP

       MFS_1 277 lllallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdla.ppeeagtasglfntagslggalg 352
                 + + +++++ + +g++++  +s++++++++++++ +g+  +++++ a++  ++ p +++++a+ +f ++g+l+++++
  EEA20499.1 350 TPFLVGCCVPVIVGYLICVGSSNPHAGYAGMFILVLGVYPISTLVVAWVGTNIsPDSKRAFALPYFYSIGNLSMLVS 426
                 9999999999999999999999**************88888888888888888688****************99876 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.7  19.1   9.6e-22   3.4e-18      67     410 ..     113     434 ..      81     467 .. 0.82

  Alignments for each domain:
  == domain 1  score: 65.7 bits;  conditional E-value: 9.6e-22
                 HHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS CS
    Sugar_tr  67 gllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnkts 165
                  l+++rfG   +l +a +l +  ++ +a+ k   ++ + i+ R+l+G +  ++s     + + i p++l+g+ v++++la  +   ++  f +++++++
  EEA20499.1 113 VLAVKRFGANRALGTALLLWSCVTLATAFVK---TYGQAIAVRMLLGACEAGVSPSFAYLFATIYPQRLAGKRVMMTNLANCTSGAFGGLFAYAVQQMG 208
                 5678999999999999999999999999999...9*************99999999999999999**************98777777777777776666 PP

                 -...TTHHHHHHHCCHHHHHHH.HHHGGGS---H..HHHHHTT-HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH.....HTTHHHHSH...HHHHH CS
    Sugar_tr 166 n...adgwrillglqlvpalll.lilllflPESP..rylvekgkeeeakevlaklrgeedadrelaeekdsleaeqeeekaswkellssktvrqrllig 258
                 +      wr+l+ +++  + ++  i+++ lP SP   ++++ +  e+ ++ l+k      + +e    kd l+++       w     +++ + +++++
  EEA20499.1 209 ErrgIAAWRWLFIVEFCVTFVVgGIGWCILPHSPetAWFLSEE--EKETMRLRK------KRDETFRGKDILDKK-------WI----KMSLKDPFIYV 288
                 6677579*******99888444168889***999444666655..444444555......334444455555555.......32....233445***** PP

                 HHHHHHHHHTTHHHHHHHTTTHHHHSS-THH..HHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHH CS
    Sugar_tr 259 vvlqifqqltGinaimyysptifenlglsks..llvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgivalllvakskaasivaivf 355
                 +++++f+  + i  +  + pti+  lg+      ++ti v+vv +++ +   +++d+f RRt +l+G+++  i+  +++    +++++    ++ a + 
  EEA20499.1 289 CGIAFFTSSVAITGFGVFLPTIIAGLGFAALkvNYMTIPVYVVGAISLVTCCYFSDKFNRRTPFLVGCCVPVIVGYLIC----VGSSNP--HAGYAGM- 380
                 *****************************99999*************************************99999998....666665..3444554. PP

                 HHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Sugar_tr 356 ialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfpiit 410
                 ++l++ ++ ++   v wv  + ++p s R++al + + + +l+ ++ s+l+p+ +
  EEA20499.1 381 FILVLGVYPISTLVVAWVG-TNISPDSKRAFALPYFYSIGNLSMLVSSQLYPTQD 434
                 4556699***********9.9*******************************976 PP

>> DUF4131  Domain of unknown function (DUF4131)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.1      0.06   2.2e+02      14      54 ..     195     242 ..     187     260 .. 0.67
   2 ?    4.6   0.1    0.0062        22      10      55 ..     329     374 ..     323     383 .. 0.65
   3 ?    0.7   0.0       0.1   3.7e+02       8      64 ..     383     440 ..     375     451 .. 0.72

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.06
     DUF4131  14 lllllllllllrr.......rprrrvllllllllllallgfalrapqp 54 
                 ++  l+++++++        ++r+ +++ +++ ++++++g+++  ++p
  EEA20499.1 195 AFGGLFAYAVQQMgerrgiaAWRWLFIVEFCVTFVVGGIGWCILPHSP 242
                 444455555544456778666677777777777777777777666555 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.0062
     DUF4131  10 lalllllllllllllrrrprrrvllllllllllallgfalrapqpn 55 
                  +++++ l+++++++ + +rr+ +l+ + + +++++ +++ + +p+
  EEA20499.1 329 YVVGAISLVTCCYFSDKFNRRTPFLVGCCVPVIVGYLICVGSSNPH 374
                 4566666777777666566666666666666777776776666665 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 0.1
     DUF4131   8 vllalllllllllllllrr...rprrrvllllllllllallgfalrapqpnandlsqlle 64 
                 ++l++  + +l+ +++       p  +++++l +++ ++ l ++++++  +++d +++++
  EEA20499.1 383 LVLGVYPISTLVVAWV--GtniSPDSKRAFALPYFYSIGNLSMLVSSQLYPTQDGPRYVK 440
                 3333333333433333..244799999999999999999999999999999999999986 PP

>> DUF2207  Predicted membrane protein (DUF2207)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   2.5   5.2e-05      0.19     384     439 ..     297     351 ..     249     353 .. 0.70
   2 ?   -1.4   0.4       0.2   7.2e+02     415     428 ..     381     394 ..     352     483 .. 0.45

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 5.2e-05
     DUF2207 384 salglgliilglilillallllvll..............lvfllilllillliaiivlllfsrllgrrte 439
                 s++++g+++               +              ++++ i++++++ i+++ +++fs  + rrt+
  EEA20499.1 297 SVAITGFGV---------------FlptiiaglgfaalkVNYMTIPVYVVGAISLVTCCYFSDKFNRRTP 351
                 222222222...............022223444445555*****************************97 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.2
     DUF2207 415 lllillliaiivll 428
                 ++l+l++  i  l+
  EEA20499.1 381 FILVLGVYPISTLV 394
                 22222222222111 PP

>> TauE  Sulfite exporter TauE/SafE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   7.3    0.0003       1.1     129     197 ..      88     156 ..      53     183 .. 0.80
   2 ?    2.3   0.8      0.03   1.1e+02      36     206 ..     183     232 ..     161     257 .. 0.47
   3 ?    6.0   6.6    0.0023       8.1     128     208 ..     284     366 ..     255     418 .. 0.78

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0003
        TauE 129 vligglvGllsGllGiGgGfllvpllllllglplkkavatslllilvislagalgyalagavdwpllll 197
                 +l gg+ G +++ll+++  ++ vp +l + ++   +a +t+lll  +++la+a++  ++ a+ +++ll 
  EEA20499.1  88 GLHGGMFGNITTLLSVSFIIFEVPWVLAVKRFGANRALGTALLLWSCVTLATAFVKTYGQAIAVRMLLG 156
                 4568889*********************************************99976666666665544 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.03
        TauE  36 avatsllavvatslsgalahrrrgnvdwrlllllllgsliGallGallllllpsellkllfgvlllllallmllrkkrsrakgrerrptaillvliggl 134
                 + +t+l+  + ++++g++a+                                                                               
  EEA20499.1 183 VMMTNLANCTSGAFGGLFAY------------------------------------------------------------------------------- 202
                 34455544444444455555............................................................................... PP

        TauE 135 vGllsGllGiGgGfllvpllllllglplkkavatslllilvislagalgyal......agavdwpllll..llpgallGa 206
                                                                   a+       g   w++l++  + ++ ++G+
  EEA20499.1 203 --------------------------------------------------AVqqmgerRGIAAWRWLFIveFCVTFVVGG 232
                 ..................................................333333443333333333333333333333 PP

  == domain 3  score: 6.0 bits;  conditional E-value: 0.0023
        TauE 128 lvligglvGllsGllGiGgGfllvpllllllglplkkavatslllilvislagalgyalagavdwpllll..llpgallGall 208
                  ++  ++++++++ + i g  + +p+ +  lg+   k++ +++ + +v +++ ++  +++  ++ ++ +l    +++++G l+
  EEA20499.1 284 PFIYVCGIAFFTSSVAITGFGVFLPTIIAGLGFAALKVNYMTIPVYVVGAISLVTCCYFSDKFNRRTPFLvgCCVPVIVGYLI 366
                 3455566**********99999**********************999999999888888777775543332377777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (495 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       632  (0.0352502); expected 358.6 (0.02)
Passed bias filter:                      356  (0.0198561); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.68u 0.32s 00:00:01.00 Elapsed: 00:00:00.52
# Mc/sec: 2840.58
//
Query:       EEA20500.1  [L=303]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.8e-10   40.5   0.0    3.4e-10   40.3   0.0    1.1  1  NMT1            NMT1/THI5 like
    9.5e-06   25.2   0.0    1.4e-05   24.6   0.0    1.2  1  SBP_bac_3       Bacterial extracellular solute-binding protei
    0.00095   18.9   0.0     0.0023   17.7   0.0    1.6  2  NMT1_2          NMT1-like family
     0.0016   18.0   0.0     0.0022   17.7   0.0    1.2  1  Phosphonate-bd  ABC transporter, phosphonate, periplasmic sub


Domain annotation for each model (and alignments):
>> NMT1  NMT1/THI5 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.3   0.0   7.5e-14   3.4e-10       3     213 ..      14     226 ..      12     229 .. 0.77

  Alignments for each domain:
  == domain 1  score: 40.3 bits;  conditional E-value: 7.5e-14
                 GGHHHHHHHHTTHHHHTTEEEEEE--SSTTHHHHHHHCTS-SEEEE-HHHHHHHHHTT--EEEEEEEE-S--EEEEEECCC--SSGGGGTTSEEEE-S- CS
        NMT1   3 nhaglyvAkekGYFkeeGldVeivepadpsdatelvasgkadfgvsyqesllaarakglpvvsvaallqeplsglivlkdsgikspkDLkGkrigyvgs 101
                 n  + y+A  +G+Fke Gl+V +  p++   +++ +a g ad ++       + r    + +++a++ ++ + +l+ + ds   ++++++Gk++ +  +
  EEA20500.1  14 NYLPEYIATRHGFFKELGLEVSVTVPQPWDLVLDELADGTADAALGGIWVPSMYRNTVKEYTAFAQVSNRCPLALVKRGDSTDFNVAEIRGKTVLMKSG 112
                 67899*****************************************999999999999999*********************99**********98875 PP

                 TT..HHHHHHHHHHHTT--GGG-EEE.E-.TT-HHHHHHCTSSSEEECEETTTHHHHHHHTT-..-EEEE-GGGTT-----SEEEEEEHHHHHH-.HHH CS
        NMT1 102 pf..ekallkallakdggdpsdvtlv.nvggtslakalltgkvDaaiggyenwegvelesegk..elrifaladlgvpdyyslvlitnekllken.pel 194
                 +      ++k ll+++g+dp++v  + + +g  l+ +l +g    ++ ++ n+ +  + ++    +l + +++d g  ++   v++ +++++  +  ++
  EEA20500.1 113 NGasVGLFFKMLLKENGVDPKSVDYIqDLDGVMLS-KLFQGGMGDYF-VIDNVSARIMVEKNPklSLAMEMVKDGG--EIPWSVYYRETATITPEvLDA 207
                 551134678999***********965156666665.55555444344.4555444443333332366677777777..577777777777766431466 PP

                 HHHHHHHHHHHHHHHHHSH CS
        NMT1 195 vkkFlrAlkkGyeyalahP 213
                  k+F   l k+++++l+h 
  EEA20500.1 208 QKRFCIGLDKAIKWILEHD 226
                 6778888888888888775 PP

>> SBP_bac_3  Bacterial extracellular solute-binding proteins, family 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.6   0.0   3.1e-09   1.4e-05      33     181 ..      27     182 ..      22     201 .. 0.73

  Alignments for each domain:
  == domain 1  score: 24.6 bits;  conditional E-value: 3.1e-09
                 HHHCT-EEEEEE.-SGGGHHHHHHTTSSSEEESSEB-.-HHH...HTTEEEESESEEEEEEEEEEETTSHGTCCHSSCGCGTTSEEEEETTSH.HHHH. CS
                 xxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxx.xxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxx. RF
   SBP_bac_3  33 akrlgvkvefvp.vswdelipalksgkvDiaiaaiti.tpeR...eekvdFsqpyfsagqvllvrkkdaskissiksladLkgkkvgvqagst.aeel. 124
                  k+lg++v ++  ++wd ++++l++g +D+a ++i + +  R   +e  +F q   + +++l+ r +d+   ++++ +a++ gk+v    g   +  l 
  EEA20500.1  27 FKELGLEVSVTVpQPWDLVLDELADGTADAALGGIWVpSMYRntvKEYTAFAQVSNRCPLALVKR-GDS---TDFN-VAEIRGKTVLMKSGNGaSVGLf 120
                 689****8877636*********************985334433378899999999999999998.654...6886.88*****999999854233334 PP

                 ....HHHHHHC...TSEEE.EESSHHHH.HHH.HHTTSSSEEEEEHHHHHHHHHHCCGCCEEEEECG CS
                 ....xxxxxxx...xxxxx.xxxxxxxx.xxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   SBP_bac_3 125 ....lkeelkk...gaeiv.efdtleea.lqa.Lkngrvdavvadspvlaylvkknpdkkvvlveep 181
                     lk    +   + + v + ++l+ + l +  + g  d++v d+++++ +v+knp++ + + e +
  EEA20500.1 121 fkmlLK----EngvDPKSVdYIQDLDGVmLSKlFQGGMGDYFVIDNVSARIMVEKNPKLSLAM-EMV 182
                 333344....24444444414466666634452566678*******************99998.433 PP

>> NMT1_2  NMT1-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0     5e-07    0.0023      17      62 ..      14      59 ..       8      89 .. 0.89
   2 ?   -3.6   0.0       1.5   6.9e+03     138     153 ..     120     134 ..     114     157 .. 0.75

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 5e-07
      NMT1_2 17 daaplvvakekglfakeGltvelekqaswaelrdkllagelDaahv 62
                ++ p  +a   g+f++ Gl+v+++  + w  ++d+l++g  Daa+ 
  EEA20500.1 14 NYLPEYIATRHGFFKELGLEVSVTVPQPWDLVLDELADGTADAALG 59
                6778899************************************975 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 1.5
      NMT1_2 138 llrywLaaaGldpead 153
                  ++++L+++G+dp + 
  EEA20500.1 120 FFKMLLKENGVDP-KS 134
                 5788999999999.33 PP

>> Phosphonate-bd  ABC transporter, phosphonate, periplasmic substrate-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0   4.8e-07    0.0022      25     146 ..      28     141 ..      22     231 .. 0.83

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 4.8e-07
                     HHHSSEEEEE--SSHHHHHHHHHTTS-SEEE--HHHHHHHHHH.S-EEEEEEEEETT--SEEEEEEEEETTSS--SHHHHGG-EEEE--TT-TTT CS
  Phosphonate-bd  25 eelGvevelvvatdyaavvealragqvDiaflgplayvqardq.agveplatrvrsdGsasyrsviivradsdiqsledLkgktiafvspsStsG 118
                     +elG ev ++v +  + v  +l+ g++D a+ g      +r+  ++++++a+ ++     +   +++ r ds+  ++++++gkt+ + s + +s 
      EEA20500.1  28 KELGLEVSVTVPQPWDLVLDELADGTADAALGGIWVPSMYRNTvKEYTAFAQVSN-----RCPLALVKRGDSTDFNVAEIRGKTVLMKSGNGASV 117
                     79****************************99988888888775699******98.....888888888888755******************** PP

                     THHHHHHTCCCCT--HH..HHSSEEEE--H CS
  Phosphonate-bd 119 ylvpaalLvkeagldpe..ddfsevfsgsh 146
                      l+ ++lL ke+g+dp+  d     + ++ 
      EEA20500.1 118 GLFFKMLL-KENGVDPKsvD-----YIQDL 141
                     ******9*.9*****98331.....33333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (303 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       370  (0.020637); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 2040.52
//
Query:       EEA20501.1  [L=668]
Description: hypothetical protein PMAA_043380 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.2e-17   62.1   0.4    8.3e-17   61.1   0.1    1.6  2  Fungal_trans  Fungal specific transcription factor domain
  ------ inclusion threshold ------
      0.029   14.5   1.4      0.057   13.5   1.4    1.5  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.1   0.0      0.72   6.4e+03     146     158 ..     224     236 ..     216     248 .. 0.70
   2 !   61.1   0.1   9.2e-21   8.3e-17      72     187 ..     292     399 ..     266     412 .. 0.83

  Alignments for each domain:
  == domain 1  score: -4.1 bits;  conditional E-value: 0.72
  Fungal_trans 146 eeeaesrrRlwwa 158
                   ++  esr R+w++
    EEA20501.1 224 PNSPESRDRIWLC 236
                   4556777777776 PP

  == domain 2  score: 61.1 bits;  conditional E-value: 9.2e-21
  Fungal_trans  72 fplraeilihedfsspssslwilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktial 168
                   f+ +a +l+  +  ++  s ++++ ++l++ly+  + +++ ++++ gv  r++  l Lh+++s++       +++ e+e ++Rlww++F++D++ ++
    EEA20501.1 292 FFEQALKLL--KVPYEEISAEHIEVFNLIALYSYSLNRQRTAYMYAGVSSRMCNVLQLHKKSSSED------RTPVEREHLKRLWWSTFCIDRMSST 380
                   455666666..4444455569*********************************************......77777******************** PP

  Fungal_trans 169 klGrppllddsqinlpLPc 187
                   ++G  p+l  +qi++ +P 
    EEA20501.1 381 QMGLLPNLQIDQIDIDYPS 399
                   ******99******99996 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   1.4   6.4e-06     0.057      15      38 ..       5      26 ..       3      28 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 6.4e-06
                TSSSS-HHHHHCTHHHCCCCTCCC CS
     Zn_clus 15 akkPaCsnCkklnleCtfysessk 38
                +++P C+nC+  n+ Ct y  + +
  EEA20501.1  5 KRNP-CRNCAFANASCT-YATPDR 26
                589*.************.776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (668 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       459  (0.025601); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.48
# Mc/sec: 4182.14
//
Query:       EEA20502.1  [L=316]
Description: chitin deacetylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    0.00057   19.8   0.0     0.0013   18.6   0.0    1.6  2  Polysacc_deac_1  Polysaccharide deacetylase


Domain annotation for each model (and alignments):
>> Polysacc_deac_1  Polysaccharide deacetylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0      0.35   6.3e+03      95     108 ..      16      29 ..      15      37 .. 0.80
   2 !   18.6   0.0   7.4e-08    0.0013      15     112 ..      78     177 ..      75     186 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 0.35
                      S----EEE-GGGEE CS
  Polysacc_deac_1  95 greprlfryPygsa 108
                      g +p  f +P+g+ 
       EEA20502.1  16 GANPPKFTWPGGKK 29 
                      67888899999975 PP

  == domain 2  score: 18.6 bits;  conditional E-value: 7.4e-08
                      ESSCSCHHHHHHHHHHCT--EEEEE-HHHHCH-HHHHHHHHHTTEEEEE--SS--EGGGSHHHHHHHHHHHHHHHHHHHHS----E..EE-GGG CS
  Polysacc_deac_1  15 dgprdntteilpvLkkykvkatffvigglvedypdevremaasGveignHtinhsnlkrlseeevrreierakdalrkalgreprl..fryPyg 106
                       g+r +  ++l ++k+ +v+  +f++++    +p  +++++ + ++i +H++      +l+ee +r+++ r+ d   + +g++      r+P+ 
       EEA20502.1  78 YGTRVGIWRLLRIFKEFDVPYSVFLSSEALLVNPAFAEKLKTENCDIVSHGTRSISRLNLTEEMERADLRRSIDQTLELTGKRILGafPRPPTT 171
                      567788899*******************999999************************************************998764567766 PP

                      EE-HHH CS
  Polysacc_deac_1 107 sasatv 112
                        s+++
       EEA20502.1 172 GNSRRI 177
                      666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (316 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       300  (0.0167327); expected 358.6 (0.02)
Passed bias filter:                      295  (0.0164538); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.23s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 2294.58
//
Query:       EEA20503.1  [L=103]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (103 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       433  (0.0241508); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.36u 0.27s 00:00:00.63 Elapsed: 00:00:00.42
# Mc/sec: 744.26
//
Query:       EEA20504.1  [L=715]
Description: guanine nucleotide exchange factor Vps9, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.8e-31  106.8   0.0    1.1e-30  106.0   0.0    1.5  1  VPS9        Vacuolar sorting protein 9 (VPS9) domain
    5.2e-15   55.5   0.1    1.8e-14   53.8   0.1    2.0  1  DUF5601     Domain of unknown function (DUF5601)
    2.6e-09   36.6   0.1    3.3e-08   33.1   0.0    2.3  2  CUE         CUE domain
  ------ inclusion threshold ------
      0.039   14.2   2.6      0.066   13.4   0.5    2.2  2  HCMV_UL124  Family of unknown function
       0.38   11.2   1.4        0.8   10.2   0.2    2.2  2  SCIMP       SCIMP protein


Domain annotation for each model (and alignments):
>> VPS9  Vacuolar sorting protein 9 (VPS9) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.0   0.0   2.9e-34   1.1e-30       3     103 ..     431     530 ..     429     531 .. 0.97

  Alignments for each domain:
  == domain 1  score: 106.0 bits;  conditional E-value: 2.9e-34
        VPS9   3 qaseeLkklseaksPreKlkcllrtieeiteavskseegeslgaDdlLPiliyviikssppnlysnvqfikrFrsktllegeegYylttleaavefies 101
                  a++eL+k++ ++ Pr+K+ c+l++++ i+ ++ k++++ +++aD + Piliyv++k++p++l+snvq+i rFr++++l ge+gYyl++l+ a++fie+
  EEA20504.1 431 LAQQELSKIKGYRAPRDKVICILNCCKVIFGLL-KHSKNPDTSADSFVPILIYVVLKANPEHLVSNVQYILRFRNQDKLGGEAGYYLSSLSGAIQFIET 528
                 699******************************.999999**********************************************************9 PP

        VPS9 102 le 103
                 l+
  EEA20504.1 529 LD 530
                 86 PP

>> DUF5601  Domain of unknown function (DUF5601)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.8   0.1     5e-18   1.8e-14       1      65 []     289     353 ..     289     353 .. 0.98

  Alignments for each domain:
  == domain 1  score: 53.8 bits;  conditional E-value: 5e-18
     DUF5601   1 KqiksfvrkisqrsisieelSemVqdFyqnlaerlnktplyktvsseavedlldeiEkyimtrlY 65 
                 K ++sf++++ ++++ + e++++++dF+ ++++++ + +++++vs+ + +++ +++Ek++m+rlY
  EEA20504.1 289 KFLRSFLTEFGKKQWLVHEQVKIISDFLAFITNKMAQCEVWRHVSDAEFDNAKEGMEKLVMNRLY 353
                 6689************************************************************9 PP

>> CUE  CUE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.1     0.099   3.6e+02      29      41 ..     543     555 ..     539     556 .. 0.83
   2 !   33.1   0.0   9.2e-12   3.3e-08       2      42 .]     672     712 ..     671     712 .. 0.94

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.099
                 TTHHHHHHHHHHC CS
         CUE  29 gnvEatinaLLeg 41 
                  nvEa+++a+ ++
  EEA20504.1 543 KNVEAAVSAIAQE 555
                 69*******9875 PP

  == domain 2  score: 33.1 bits;  conditional E-value: 9.2e-12
                 HHHHHHHHHHSTTS-HHHHHHHHHHCTTTHHHHHHHHHHCC CS
         CUE   2 eqmletLkemFPdldeevIravLrasngnvEatinaLLegs 42 
                  + +etL+ mFP+ld+++I +v r + g+v ++++a+L +s
  EEA20504.1 672 RDVVETLSGMFPNLDKDIIDDVVRMKEGRVGLAVDACLALS 712
                 5789**********************************886 PP

>> HCMV_UL124  Family of unknown function
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.1      0.55     2e+03      74     104 ..     130     162 ..     128     175 .. 0.77
   2 ?   13.4   0.5   1.8e-05     0.066      18     115 ..     552     646 ..     542     652 .. 0.73

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.55
  HCMV_UL124  74 slastvrskelps..dhepleaweqgsdveapp 104
                  l s    kelps  + e le  ++g +v+   
  EEA20504.1 130 GLPSEYTEKELPSvpQDEQLEDRQKGGEVNDDD 162
                 567788899***955689999999999998655 PP

  == domain 2  score: 13.4 bits;  conditional E-value: 1.8e-05
  HCMV_UL124  18 dsqqntt.qlpassaaalslpsasavqahspssfsdtyptatalcgtlvvvgivlclslastvrskelpsdhepleaweqgsdveapplpekspcpehv 115
                  +q+n   +  +ss+     psa a      s   d+ pt+t       v g++  +    +   + +  d ep     q s  ++pplpe+ p+pe +
  EEA20504.1 552 IAQENMKaESETSSTQVTPRPSADA---ERHSQRRDAGPTTTNEGENAPVAGLLRSIQKPLSSIGRIFSEDSEPDRR-TQQSSANTPPLPERGPAPERI 646
                 4555543133445555555666654...4556778999****99999999999998887766677788999999765.5667789************87 PP

>> SCIMP  SCIMP protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.1       3.8   1.4e+04      63      74 ..     355     366 ..     320     382 .. 0.52
   2 ?   10.2   0.2   0.00022       0.8      61     124 ..     625     691 ..     604     698 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 3.8
       SCIMP  63 nqspvqlPplPP 74 
                 + ++  +Pp PP
  EEA20504.1 355 QTFSPAIPPPPP 366
                 223444555554 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.00022
       SCIMP  61 vlnqspvqlPplPPrgllssedsspqetksqp....patyslvnkvrnkktvsipsyiePeedyddve 124
                  ++qs+ + PplP rg   +e+   qe+ +++    +a    +++v+++ +v++ s + P+ d d ++
  EEA20504.1 625 RTQQSSANTPPLPERGPA-PERIDAQEAAARQasaeAAEARRIQRVEHRDVVETLSGMFPNLDKDIID 691
                 57899**********965.44444444433331111556678999999********999999988665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (715 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       803  (0.0447878); expected 358.6 (0.02)
Passed bias filter:                      462  (0.0257683); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.65u 0.26s 00:00:00.91 Elapsed: 00:00:00.41
# Mc/sec: 5257.82
//
Query:       EEA20505.1  [L=705]
Description: guanine nucleotide exchange factor Vps9, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.7e-31  106.8   0.0      1e-30  106.0   0.0    1.5  1  VPS9        Vacuolar sorting protein 9 (VPS9) domain
      5e-15   55.6   0.1    1.7e-14   53.8   0.1    2.0  1  DUF5601     Domain of unknown function (DUF5601)
    7.4e-05   22.4   0.1    0.00093   18.9   0.0    2.3  2  CUE         CUE domain
  ------ inclusion threshold ------
      0.039   14.2   2.6      0.064   13.4   0.5    2.2  2  HCMV_UL124  Family of unknown function
       0.37   11.3   1.4       0.78   10.2   0.2    2.2  2  SCIMP       SCIMP protein


Domain annotation for each model (and alignments):
>> VPS9  Vacuolar sorting protein 9 (VPS9) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.0   0.0   2.9e-34     1e-30       3     103 ..     431     530 ..     429     531 .. 0.97

  Alignments for each domain:
  == domain 1  score: 106.0 bits;  conditional E-value: 2.9e-34
        VPS9   3 qaseeLkklseaksPreKlkcllrtieeiteavskseegeslgaDdlLPiliyviikssppnlysnvqfikrFrsktllegeegYylttleaavefies 101
                  a++eL+k++ ++ Pr+K+ c+l++++ i+ ++ k++++ +++aD + Piliyv++k++p++l+snvq+i rFr++++l ge+gYyl++l+ a++fie+
  EEA20505.1 431 LAQQELSKIKGYRAPRDKVICILNCCKVIFGLL-KHSKNPDTSADSFVPILIYVVLKANPEHLVSNVQYILRFRNQDKLGGEAGYYLSSLSGAIQFIET 528
                 699******************************.999999**********************************************************9 PP

        VPS9 102 le 103
                 l+
  EEA20505.1 529 LD 530
                 86 PP

>> DUF5601  Domain of unknown function (DUF5601)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.8   0.1   4.9e-18   1.7e-14       1      65 []     289     353 ..     289     353 .. 0.98

  Alignments for each domain:
  == domain 1  score: 53.8 bits;  conditional E-value: 4.9e-18
     DUF5601   1 KqiksfvrkisqrsisieelSemVqdFyqnlaerlnktplyktvsseavedlldeiEkyimtrlY 65 
                 K ++sf++++ ++++ + e++++++dF+ ++++++ + +++++vs+ + +++ +++Ek++m+rlY
  EEA20505.1 289 KFLRSFLTEFGKKQWLVHEQVKIISDFLAFITNKMAQCEVWRHVSDAEFDNAKEGMEKLVMNRLY 353
                 6689************************************************************9 PP

>> CUE  CUE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.1     0.098   3.5e+02      29      41 ..     543     555 ..     539     556 .. 0.83
   2 !   18.9   0.0   2.6e-07   0.00093       2      29 ..     672     699 ..     671     700 .. 0.89

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.098
                 TTHHHHHHHHHHC CS
         CUE  29 gnvEatinaLLeg 41 
                  nvEa+++a+ ++
  EEA20505.1 543 KNVEAAVSAIAQE 555
                 69*******9875 PP

  == domain 2  score: 18.9 bits;  conditional E-value: 2.6e-07
                 HHHHHHHHHHSTTS-HHHHHHHHHHCTT CS
         CUE   2 eqmletLkemFPdldeevIravLrasng 29 
                  + +etL+ mFP+ld+++I +v r + g
  EEA20505.1 672 RDVVETLSGMFPNLDKDIIDDVVRMKEG 699
                 5789****************99998877 PP

>> HCMV_UL124  Family of unknown function
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.1      0.54   1.9e+03      74     104 ..     130     162 ..     128     175 .. 0.77
   2 ?   13.4   0.5   1.8e-05     0.064      18     115 ..     552     646 ..     542     652 .. 0.73

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.54
  HCMV_UL124  74 slastvrskelps..dhepleaweqgsdveapp 104
                  l s    kelps  + e le  ++g +v+   
  EEA20505.1 130 GLPSEYTEKELPSvpQDEQLEDRQKGGEVNDDD 162
                 567788899***955689999999999998655 PP

  == domain 2  score: 13.4 bits;  conditional E-value: 1.8e-05
  HCMV_UL124  18 dsqqntt.qlpassaaalslpsasavqahspssfsdtyptatalcgtlvvvgivlclslastvrskelpsdhepleaweqgsdveapplpekspcpehv 115
                  +q+n   +  +ss+     psa a      s   d+ pt+t       v g++  +    +   + +  d ep     q s  ++pplpe+ p+pe +
  EEA20505.1 552 IAQENMKaESETSSTQVTPRPSADA---ERHSQRRDAGPTTTNEGENAPVAGLLRSIQKPLSSIGRIFSEDSEPDRR-TQQSSANTPPLPERGPAPERI 646
                 4555543133445555555666654...4556778999****99999999999998887766677788999999765.5667789************87 PP

>> SCIMP  SCIMP protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.1       3.7   1.3e+04      63      74 ..     355     366 ..     320     382 .. 0.52
   2 ?   10.2   0.2   0.00022      0.78      61     124 ..     625     691 ..     604     698 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 3.7
       SCIMP  63 nqspvqlPplPP 74 
                 + ++  +Pp PP
  EEA20505.1 355 QTFSPAIPPPPP 366
                 223444555554 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.00022
       SCIMP  61 vlnqspvqlPplPPrgllssedsspqetksqp....patyslvnkvrnkktvsipsyiePeedyddve 124
                  ++qs+ + PplP rg   +e+   qe+ +++    +a    +++v+++ +v++ s + P+ d d ++
  EEA20505.1 625 RTQQSSANTPPLPERGPA-PERIDAQEAAARQasaeAAEARRIQRVEHRDVVETLSGMFPNLDKDIID 691
                 57899**********965.44444444433331111556678999999********999999988665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (705 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       792  (0.0441742); expected 358.6 (0.02)
Passed bias filter:                      450  (0.025099); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.66u 0.29s 00:00:00.95 Elapsed: 00:00:00.45
# Mc/sec: 4718.52
//
Query:       EEA20506.1  [L=532]
Description: guanine nucleotide exchange factor Vps9, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-27   96.4   0.0      2e-27   95.4   0.0    1.4  1  VPS9      Vacuolar sorting protein 9 (VPS9) domain
      4e-15   55.9   0.1    1.2e-14   54.4   0.1    1.9  1  DUF5601   Domain of unknown function (DUF5601)


Domain annotation for each model (and alignments):
>> VPS9  Vacuolar sorting protein 9 (VPS9) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.4   0.0   2.2e-31     2e-27       3      98 ..     431     525 ..     429     529 .. 0.95

  Alignments for each domain:
  == domain 1  score: 95.4 bits;  conditional E-value: 2.2e-31
        VPS9   3 qaseeLkklseaksPreKlkcllrtieeiteavskseegeslgaDdlLPiliyviikssppnlysnvqfikrFrsktllegeegYylttleaavef 98 
                  a++eL+k++ ++ Pr+K+ c+l++++ i+ ++ k++++ +++aD + Piliyv++k++p++l+snvq+i rFr++++l ge+gYyl++l + + +
  EEA20506.1 431 LAQQELSKIKGYRAPRDKVICILNCCKVIFGLL-KHSKNPDTSADSFVPILIYVVLKANPEHLVSNVQYILRFRNQDKLGGEAGYYLSSLVSNIGH 525
                 699******************************.999999*************************************************9887665 PP

>> DUF5601  Domain of unknown function (DUF5601)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.4   0.1   1.3e-18   1.2e-14       1      65 []     289     353 ..     289     353 .. 0.98

  Alignments for each domain:
  == domain 1  score: 54.4 bits;  conditional E-value: 1.3e-18
     DUF5601   1 KqiksfvrkisqrsisieelSemVqdFyqnlaerlnktplyktvsseavedlldeiEkyimtrlY 65 
                 K ++sf++++ ++++ + e++++++dF+ ++++++ + +++++vs+ + +++ +++Ek++m+rlY
  EEA20506.1 289 KFLRSFLTEFGKKQWLVHEQVKIISDFLAFITNKMAQCEVWRHVSDAEFDNAKEGMEKLVMNRLY 353
                 6689************************************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (532 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       746  (0.0416086); expected 358.6 (0.02)
Passed bias filter:                      546  (0.0304535); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.41
# Mc/sec: 3854.74
//
Query:       EEA20507.1  [L=676]
Description: guanine nucleotide exchange factor Vps9, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.3e-31  106.9   0.0    9.7e-31  106.1   0.0    1.5  1  VPS9        Vacuolar sorting protein 9 (VPS9) domain
    4.8e-15   55.6   0.1    1.7e-14   53.9   0.1    2.0  1  DUF5601     Domain of unknown function (DUF5601)
  ------ inclusion threshold ------
      0.035   14.3   2.6       0.06   13.5   0.5    2.2  2  HCMV_UL124  Family of unknown function


Domain annotation for each model (and alignments):
>> VPS9  Vacuolar sorting protein 9 (VPS9) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.1   0.0   1.6e-34   9.7e-31       3     103 ..     431     530 ..     429     531 .. 0.97

  Alignments for each domain:
  == domain 1  score: 106.1 bits;  conditional E-value: 1.6e-34
        VPS9   3 qaseeLkklseaksPreKlkcllrtieeiteavskseegeslgaDdlLPiliyviikssppnlysnvqfikrFrsktllegeegYylttleaavefies 101
                  a++eL+k++ ++ Pr+K+ c+l++++ i+ ++ k++++ +++aD + Piliyv++k++p++l+snvq+i rFr++++l ge+gYyl++l+ a++fie+
  EEA20507.1 431 LAQQELSKIKGYRAPRDKVICILNCCKVIFGLL-KHSKNPDTSADSFVPILIYVVLKANPEHLVSNVQYILRFRNQDKLGGEAGYYLSSLSGAIQFIET 528
                 699******************************.999999**********************************************************9 PP

        VPS9 102 le 103
                 l+
  EEA20507.1 529 LD 530
                 86 PP

>> DUF5601  Domain of unknown function (DUF5601)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.9   0.1   2.8e-18   1.7e-14       1      65 []     289     353 ..     289     353 .. 0.98

  Alignments for each domain:
  == domain 1  score: 53.9 bits;  conditional E-value: 2.8e-18
     DUF5601   1 KqiksfvrkisqrsisieelSemVqdFyqnlaerlnktplyktvsseavedlldeiEkyimtrlY 65 
                 K ++sf++++ ++++ + e++++++dF+ ++++++ + +++++vs+ + +++ +++Ek++m+rlY
  EEA20507.1 289 KFLRSFLTEFGKKQWLVHEQVKIISDFLAFITNKMAQCEVWRHVSDAEFDNAKEGMEKLVMNRLY 353
                 6689************************************************************9 PP

>> HCMV_UL124  Family of unknown function
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.1      0.31   1.8e+03      74     104 ..     130     162 ..     128     175 .. 0.77
   2 ?   13.5   0.5     1e-05      0.06      18     115 ..     552     646 ..     542     652 .. 0.73

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.31
  HCMV_UL124  74 slastvrskelps..dhepleaweqgsdveapp 104
                  l s    kelps  + e le  ++g +v+   
  EEA20507.1 130 GLPSEYTEKELPSvpQDEQLEDRQKGGEVNDDD 162
                 567788899***955689999999999998655 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 1e-05
  HCMV_UL124  18 dsqqntt.qlpassaaalslpsasavqahspssfsdtyptatalcgtlvvvgivlclslastvrskelpsdhepleaweqgsdveapplpekspcpehv 115
                  +q+n   +  +ss+     psa a      s   d+ pt+t       v g++  +    +   + +  d ep     q s  ++pplpe+ p+pe +
  EEA20507.1 552 IAQENMKaESETSSTQVTPRPSADA---ERHSQRRDAGPTTTNEGENAPVAGLLRSIQKPLSSIGRIFSEDSEPDRR-TQQSSANTPPLPERGPAPERI 646
                 4555543133445555555666654...4556778999****99999999999998887766677788999999765.5667789************87 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (676 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1066  (0.0594567); expected 358.6 (0.02)
Passed bias filter:                      623  (0.0347482); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.73u 0.31s 00:00:01.04 Elapsed: 00:00:00.49
# Mc/sec: 4173.07
//
Query:       EEA20508.1  [L=600]
Description: asparagine synthase related protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.1e-13   49.7   0.1    0.00045   20.0   0.0    3.2  3  Asn_synthase  Asparagine synthase
    3.5e-06   26.9   0.0    2.2e-05   24.3   0.0    2.2  1  GATase_7      Glutamine amidotransferase domain
  ------ inclusion threshold ------
      0.065   12.7   0.0       0.14   11.6   0.0    1.4  1  DUF3700       Aluminium induced protein
      0.081   13.1   0.0       0.23   11.7   0.0    1.7  1  GATase_6      Glutamine amidotransferase domain


Domain annotation for each model (and alignments):
>> Asn_synthase  Asparagine synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.7   0.0   0.00055       2.5      16      52 ..     295     333 ..     270     352 .. 0.81
   2 !   18.2   0.1   3.5e-07    0.0016     118     143 ..     447     471 ..     429     483 .. 0.84
   3 !   20.0   0.0     1e-07   0.00045     213     259 ..     485     531 ..     478     540 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00055
  Asn_synthase  16 advpvGalLSGGlDSSliaalaarqsk..splktFsigf 52 
                   ad +v++l+SGGlD +l+a l    ++  +++    ++f
    EEA20508.1 295 ADAKVAVLFSGGLDCTLLARLSHDALPkdESIDLINVAF 333
                   799**************9998877777666666666666 PP

  == domain 2  score: 18.2 bits;  conditional E-value: 3.5e-07
  Asn_synthase 118 gvkvvLsGeGaDElfgGYpyfykaal 143
                     +v+LsG GaDElf+GY  ++  a 
    EEA20508.1 447 TARVLLSGLGADELFAGYG-RHGIAF 471
                   468***************9.997664 PP

  == domain 3  score: 20.0 bits;  conditional E-value: 1e-07
  Asn_synthase 213 ldlktllpgdllrkDrasmahglEaRvPflDhrlvevalrlppelkl 259
                   ld+ +l + +l r Dr    +g EaR+PflD ++v +  + p+ ++ 
    EEA20508.1 485 LDVGRLGKRNLGRDDRVISNWGREARFPFLDEEFVSWTTQTPVWERC 531
                   56777888899999*************************99987665 PP

>> GATase_7  Glutamine amidotransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.3   0.0     5e-09   2.2e-05      13     116 ..      73     183 ..      63     186 .. 0.66

  Alignments for each domain:
  == domain 1  score: 24.3 bits;  conditional E-value: 5e-09
    GATase_7  13 aQPmvssedgrlvivfnGeiy.......NykelreeLeakghrfrtksDtevllallea........ewgeealerlnGmfAfaiwdeeekrlllaRDr 96 
                 +QP+v+  + + v++ nGe         + ++ +  +++   +++ + D+        +        + +++++++++G f+f+ +d  ++rl+  RD 
  EEA20508.1  73 SQPLVD-TKSNSVLCWNGEAWkvngelvDGNDTELVFQKFIEAIQYHHDAG-------EleaedksvDRLTNIISNITGPFSFVFYDGVHRRLYFSRDC 163
                 688884.56666777666643000000033333322322223334444444.......044445578899***************************** PP

    GATase_7  97 lGikPLyygedk.gdallfaS 116
                 lG ++L  g+d+ g +l + S
  EEA20508.1 164 LGRRSLLHGQDDyG-KLRICS 183
                 **********9944.666655 PP

>> DUF3700  Aluminium induced protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   3.1e-05      0.14     123     170 ..     135     182 ..     123     187 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 3.1e-05
     DUF3700 123 dqvvkdleGkfafvlydskaktvfvaldadgsvplyWGiaadgsvvis 170
                  +++++++G f+fv yd  ++ ++ ++d  g+ +l  G +  g++ i+
  EEA20508.1 135 TNIISNITGPFSFVFYDGVHRRLYFSRDCLGRRSLLHGQDDYGKLRIC 182
                 5799**********************************9999998765 PP

>> GATase_6  Glutamine amidotransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   5.1e-05      0.23      26     125 ..      69     174 ..      47     182 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 5.1e-05
    GATase_6  26 laeeegaqPfpsedgrlllvhNGeiynykelreelpalkglafrsrsDtevllall.......eelG............eevlerlrGmfafaiwdkre 105
                      + qP++ ++++ +l  NGe  +++    el +         +Dte++++ +       +++G            +  ++ + G f+f+++d   
  EEA20508.1  69 DH--VTSQPLVDTKSNSVLCWNGEAWKVN---GELVD--------GNDTELVFQKFieaiqyhHDAGeleaedksvdrlTNIISNITGPFSFVFYDGVH 154
                 43..456*****************99996...44444........89*******555999999666677777777778888889*************99 PP

    GATase_6 106 ntlilardrlgvkplyyavd 125
                 ++l + rd lg++ l +++d
  EEA20508.1 155 RRLYFSRDCLGRRSLLHGQD 174
                 999999*****999998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (600 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       390  (0.0217525); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.43
# Mc/sec: 4180.80
//
Query:       EEA20509.1  [L=673]
Description: amine oxidase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
     3e-160  533.7   0.5   3.6e-160  533.4   0.5    1.1  1  Cu_amine_oxid    Copper amine oxidase, enzyme domain
    1.6e-09   37.9   0.2      3e-09   37.0   0.2    1.5  1  Cu_amine_oxidN2  Copper amine oxidase, N2 domain
    2.2e-06   28.0   0.0    5.2e-06   26.8   0.0    1.6  1  Cu_amine_oxidN3  Copper amine oxidase, N3 domain


Domain annotation for each model (and alignments):
>> Cu_amine_oxid  Copper amine oxidase, enzyme domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  533.4   0.5    6e-164  3.6e-160       2     409 ..     242     647 ..     241     648 .. 0.97

  Alignments for each domain:
  == domain 1  score: 533.4 bits;  conditional E-value: 6e-164
                    ----TT---SEEETTTEEEETTEEEEEEEETTTEEEEEEEEETTEEEEEEEEEEEEEEEE--SSHHHHH-EEEGGGT.-SGGG-----TTTSS-TT CS
  Cu_amine_oxid   2 evvqpeGpsfkvdegnlvewqkWsfrvgfnrreGlvlhdvrykgrrilyrlslsemvvpYgdprppasrkaafDlgeyglGklansLelgcDClge 97 
                    +v qp Gpsf+  +gnl++w+kW+frvgfn+reGlv+hdv+y++rr+++rls sem+vpYgdpr+p+ rkaafD+g+ g+G +an+L lgcDClg+
     EEA20509.1 242 TVSQPLGPSFQT-TGNLINWEKWRFRVGFNYREGLVIHDVTYDNRRVFHRLSSSEMFVPYGDPRAPYPRKAAFDFGNNGAGVNANNLGLGCDCLGH 336
                    689*********.8********************************************************************************** PP

                    -EEEEEEEEE..TEEEEEEEEEEEEEEE-S-SEEEE-S....EEEE--EEEEEEEEEEETTEEEEEEEEE-TTS-EEEEEEEEE----EE-T.... CS
  Cu_amine_oxid  98 ityldavladssgepvtiknaiCifEedagilwkHtdfrtgraevtrnreLvvrtiatvgNYdYifdyiFkqdGsievevratGilstaalaeeee 193
                    i+y+  ++++++g p++++n++C++E d+gilwkHt++rt++a+vtr+r Lv++t++tv+NY+Yif+++F+q+++i +evratGilsta+++++++
     EEA20509.1 337 IKYFHFWHHTNDGVPTKMSNVVCCHEIDDGILWKHTNYRTDNAVVTRSRVLVLQTVITVSNYEYIFAFQFNQAAEISYEVRATGILSTAFIDRGTS 432
                    ********************************************************************************************9999 PP

                    .GG--EEETTEE---EEEEEEEEEEE-T.SSEEEEEEEEE-T..TT.T-...-EEEEEEEEEE--BGGG-EE--.-GG-EEEEEEEEEEE-.TTS- CS
  Cu_amine_oxid 194 skygtrvapgvlasiHqHlfslrvDldidgeknsvveeelvpeepelgeenpagnafkvektvletekeaaldldpeknrvlkivnenkkn.klge 288
                     ++gt+vapgv+a++HqHlfslr+D++idg +ns++ ee++p+ p  +++ ++++++ ++++++e+e  + ld+d++ +rv+kivnen +n ++g 
     EEA20509.1 433 VPFGTVVAPGVMAPYHQHLFSLRIDPAIDGYENSIMVEESHPM-PIENPKIMTNVGYITKNEFIENE--TPLDTDNRVGRVFKIVNENIRNpVTGG 525
                    9*****************************99**********6.66778999***************..889**9888****************** PP

                    EEEEEEE-S----..---SS-TTTTTTTGGGG-SEEEEE--TT---S--TTGG-TTS.---GGGG-.S--....B-SSEEEEEEEEEEEEE---GG CS
  Cu_amine_oxid 289 pvgYklvpssaasqlllakesslvakraefakhhlwvtkykdselyaageynnqskgepvglakwvedne....sieneDlVvWvtlGltHvprae 380
                    pvgYklvp  ++sq+lla++ss++  r ef ++ +wvt+++d+el+aage++ qs++   g+a+w++ ++    s++n+DlV+W+t+G+tH+pr+e
     EEA20509.1 526 PVGYKLVP--HYSQMLLAHPSSYHSIRSEFGDYPVWVTRHHDDELFAAGEHTLQSTTG-SGVATWIKSRRanpeSVRNQDLVLWHTFGTTHNPRVE 618
                    ********..6799**************************************999884.7******8765555599******************** PP

                    GSS-TTTSEEEEEEEEES-SSS-GGGG-S CS
  Cu_amine_oxid 381 DfPvmpvetvsflLkPvnFfdenpaldvp 409
                    D+Pvmpve+++++LkPvnFf++npaldvp
     EEA20509.1 619 DWPVMPVEKMTVVLKPVNFFTRNPALDVP 647
                    ***************************98 PP

>> Cu_amine_oxidN2  Copper amine oxidase, N2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.0   0.2   5.1e-13     3e-09       1      82 [.       5      92 ..       5      96 .. 0.87

  Alignments for each domain:
  == domain 1  score: 37.0 bits;  conditional E-value: 5.1e-13
                     HHHHHHHHHHHHHCCCCCCCCTCT-TTSEEEEEEEEE---HHHHHHH......HHCH---S-EEEEEEEEETSSS..SEEEEEEEEEECC CS
  Cu_amine_oxidN2  1 hpLdaltaaeinkvesilkssaletskknsffeveLeePdKkavlqf......lekgeppppRkAsvvilfGkqt..kelvvdLatgkll 82
                     hpLd+lt++ei+ +  i+++s+   s+++ f  ++L eP+Kk  + +      +e+ + pppR A+v   + k t    + vdL+ +k+ 
       EEA20509.1  5 HPLDPLTPQEISLAAHIVRNSF--PSNDLIFRAITLWEPPKKELIPYleaerlKEQPPSPPPRIAQVLFYVDKATqfRRGRVDLVQKKVT 92
                     9*********************..899********************8887755666666*******98876666448899999999986 PP

>> Cu_amine_oxidN3  Copper amine oxidase, N3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.0   8.7e-10   5.2e-06       3      82 ..     104     186 ..     102     198 .. 0.84

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 8.7e-10
                      --HHHHHHHHHHHHTGGGGHHHHHHHHTTT.T---EEEE--SS-SSST.T--EEEEEEEE--SSS...-GCGSEEE.EEEEEE CS
  Cu_amine_oxidN3   3 vlleelaeieevikelpqfkealkkrgienldkvvltpltvgyrgeksegkRllkalvyyrtesa...nlyahPiegLellvD 82 
                      v++ e++++e++  +++ +++a+k   + + + vv++p+t  ++g ++ ++R      y++ +     n ya P+e +  l D
       EEA20509.1 104 VDAGEMKKCEKACLDDSRVQAAIKALQLPEGAVVVCDPWTYSPDGMNDMTRRCVMCFFYMKLSPHgdaNHYAYPLEFIAELSD 186
                      7889***********************55679****************99999999999998766668********6555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (673 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       453  (0.0252663); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.61u 0.29s 00:00:00.89 Elapsed: 00:00:00.49
# Mc/sec: 4169.56
//
Query:       EEA20510.1  [L=309]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    7.2e-08   32.0   0.2      2e-07   30.5   0.2    1.7  1  PNP_UDP_1  Phosphorylase superfamily


Domain annotation for each model (and alignments):
>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.5   0.2   1.1e-11     2e-07       2     229 ..      14     303 ..      13     308 .. 0.82

  Alignments for each domain:
  == domain 1  score: 30.5 bits;  conditional E-value: 1.1e-11
                 EEEEESSHHHHHHHHHHEEEEEEEEEE....TTEEEEEEEETTEEEEEEE--SSHHHHHHHHHHHHHHHC--SEEEEEEEEEES...STTT-TT-EEEE CS
   PNP_UDP_1   2 iaiivgspgevellaespleetpfgre...grgfkfvtGtlkgkpvvivstGiGkpnaavvaeirllkefgvkaiiriGtaGgl...npdlkvGDvvip 94 
                 ia i+  p e+++  +  l+e+++g +   +    +++G++++++vvi++   G    a  +++      +v+  + +G+ Gg+   + d+++GDvv+ 
  EEA20510.1  14 IAWICTLPLEMAAAQAL-LDEIHHGLPqkpNDNNAYIVGSIEKHNVVIARLPFGDQGNA--TAQLKFSFKSVRLALIVGIGGGVpseRMDIRLGDVVVG 109
                 78899999999999999.8888888777889**********************999888..44444443379************999999********* PP

                 EEEEESSSCCGCCTHHCC..................................................................TCCCCTTSSEE--HH CS
   PNP_UDP_1  95 ddainfdgrsplygpkee..................................................................gqyfpdsydapadpe 127
                 +  i++ g     + +                                                                    g +++d +  + ++ 
  EEA20510.1 110 KPGIRHGGVISIENIDAFayaysqqvrllnqpppvvlaaltklqslhltrdrrvesilaeikdrsgqnaqkfarpaqldrlflaGYHHVDANSRTCNSC 208
                 **9998888885444444888888899**999****************************999999888888888888888888666666666668888 PP

                 HHHHHHHCHHTTT..TTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTBETTCTCH.HCCCHHHHHHHHH CS
   PNP_UDP_1 128 lrallkeaaealg..ikvhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArelgipfaairvvsdlaaggadaeatheeveefaqeaakn 224
                  ++++++   ++g  + +h+G++a+++  ++++ a+++l + + + ++e E+  v  +     +p+ +ir++s      ad +++h+ ++ +a+ a   
  EEA20510.1 209 NVKMTVQRRPRNGsaPVIHYGLIASTNRMVHDSMARDKLSEAYQVNCIETEATGVMRV-----LPCFVIRGISH----YADSHRSHDWEGYAAAVAGAY 298
                 888888844444477****************************************988.....8999******9....444555555555555555555 PP

                 HHHHH CS
   PNP_UDP_1 225 aaall 229
                 a++ll
  EEA20510.1 299 AKELL 303
                 55555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       481  (0.026828); expected 358.6 (0.02)
Passed bias filter:                      434  (0.0242066); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.26s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2002.09
//
Query:       EEA20511.1  [L=253]
Description: bZIP transcription factor CpcA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.2e-06   28.5   7.8    1.9e-06   27.9   7.8    1.2  1  bZIP_2       Basic region leucine zipper
      1e-05   25.5   6.1    1.5e-05   25.0   6.1    1.2  1  bZIP_1       bZIP transcription factor
     0.0084   16.2   1.8      0.012   15.7   1.8    1.2  1  DUF5102      Domain of unknown function (DUF5102)
  ------ inclusion threshold ------
      0.016   15.0   0.2      0.016   15.0   0.2    1.5  2  PKcGMP_CC    Coiled-coil N-terminus of cGMP-dependent protein
       0.11   12.7   2.3       0.17   12.0   2.3    1.3  1  GreA_GreB_N  Transcription elongation factor, N-terminal


Domain annotation for each model (and alignments):
>> bZIP_2  Basic region leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.9   7.8   5.2e-10   1.9e-06       7      39 ..     198     230 ..     194     234 .. 0.93

  Alignments for each domain:
  == domain 1  score: 27.9 bits;  conditional E-value: 5.2e-10
                 XXXXXXXXXXXX-HHHHHHHHHHHHHHHHHHHH CS
      bZIP_2   7 erRrkNreAarrsRekkkakeeeleervkeLee 39 
                 ++R +N++Aar+sR +k +k+e++e+r+ eLe+
  EEA20511.1 198 VKRARNTMAARKSRRRKLEKQEQMEDRIRELEA 230
                 6999***************************97 PP

>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.0   6.1   4.2e-09   1.5e-05       9      41 ..     199     231 ..     196     248 .. 0.88

  Alignments for each domain:
  == domain 1  score: 25.0 bits;  conditional E-value: 4.2e-09
                 XX--HHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1   9 rkqkNReaArrsRqRKqaeieeLerrvkaLeke 41 
                 ++++N  aAr+sR+RK +++e+ e+r  +Le+ 
  EEA20511.1 199 KRARNTMAARKSRRRKLEKQEQMEDRIRELEAM 231
                 789***************************985 PP

>> DUF5102  Domain of unknown function (DUF5102)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   1.8   3.3e-06     0.012     157     269 ..     129     252 ..     114     253 .] 0.58

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 3.3e-06
     DUF5102 157 LPsleleseksssssr...ssr..vkrlkqanasstsvdssasakksrssssrrrgpppePelD......lkaarrLcattd.eaLkgltdeeLkehvk 243
                  P+ +++ e+ + + +   +++  + r ++a+ s++s++s +    s s +++ + + peP++D      +k+ar+ +a ++    k+ ++e+++++++
  EEA20511.1 129 FPDSHISGEDFDMTLAtfaQEKsgKPRPSTASMSAASPESYTDGDTS-SPKAKNKRNLPEPKFDpadpvaVKRARNTMAARKsRRRKLEKQEQMEDRIR 226
                 55555555444444333331121122333344455555555544433.334555888999998844433334555544444404556667889****** PP

     DUF5102 244 eLeelteeasevLeYwlkrrDekigd 269
                 eLe++ ++ ++  +Yw+     ++ d
  EEA20511.1 227 ELEAMLAKSEKDVQYWKAMAQTSMTD 252
                 ****************9877766655 PP

>> PKcGMP_CC  Coiled-coil N-terminus of cGMP-dependent protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.3       2.7   9.7e+03      28      33 ..     212     217 ..     212     218 .. 0.78
   2 ?   15.0   0.2   4.5e-06     0.016       7      25 ..     222     240 ..     220     244 .. 0.90

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 2.7
   PKcGMP_CC  28 rskLDK 33 
                 r+kL K
  EEA20511.1 212 RRKLEK 217
                 788887 PP

  == domain 2  score: 15.0 bits;  conditional E-value: 4.5e-06
   PKcGMP_CC   7 DERIRELEkrlaekdeEIq 25 
                 + RIRELE++la+ ++ +q
  EEA20511.1 222 EDRIRELEAMLAKSEKDVQ 240
                 68***********999887 PP

>> GreA_GreB_N  Transcription elongation factor, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   2.3   4.9e-05      0.17      50      69 ..     216     235 ..     207     236 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 4.9e-05
                  HHHHHHHHHHHHHHHHHHTE CS
  GreA_GreB_N  50 eeqaeiearIreLedkLana 69 
                  e+q+++e rIreLe++La+ 
   EEA20511.1 216 EKQEQMEDRIRELEAMLAKS 235
                  89***************975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (253 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1364  (0.0760779); expected 358.6 (0.02)
Passed bias filter:                      665  (0.0370907); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.62u 0.32s 00:00:00.94 Elapsed: 00:00:00.52
# Mc/sec: 1469.60
//
Query:       EEA20512.1  [L=61]
Description: hypothetical protein PMAA_043460 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (61 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       856  (0.0477439); expected 358.6 (0.02)
Passed bias filter:                      416  (0.0232026); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.32s 00:00:00.75 Elapsed: 00:00:00.49
# Mc/sec: 373.22
//
Query:       EEA20513.1  [L=533]
Description: conserved lysine-rich protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
      2e-37  127.9   5.0      2e-37  127.9   5.0    3.3  3  PH_6       Pleckstrin homology domain
    4.4e-06   27.2   0.0      2e-05   25.1   0.0    2.0  1  PH         PH domain
  ------ inclusion threshold ------
      0.096   12.5   0.0      0.096   12.5   0.0    2.6  3  PH_4       Pleckstrin homology domain


Domain annotation for each model (and alignments):
>> PH_6  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   1.1       1.9   1.1e+04      33      47 ..      40      52 ..      19      72 .. 0.52
   2 !  127.9   5.0   3.3e-41     2e-37       2     112 .]      87     195 ..      86     195 .. 0.95
   3 ?   -3.3   2.4       1.8   1.1e+04      23      47 ..     301     327 ..     276     343 .. 0.61

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 1.9
        PH_6 33 saedaheviawAset 47
                +a++a  + a A+et
  EEA20513.1 40 AATEA--TEAPAAET 52
                33222..22222222 PP

  == domain 2  score: 127.9 bits;  conditional E-value: 3.3e-41
        PH_6   2 flytKkffwfgtdavepkalssllksekeaesaedaheviawAsetGkGLLffsk.kedkaspsgvinLadasevaadgeqkFhltakGkkhtFkasst 99 
                 f +tK+ff+f++dave+k+l ++ +sek +++   a+ ++awA++tGkGLLf +k +edka+p+g++nL+++s+++++g+++F ++++G+kh F+asst
  EEA20513.1  87 FRFTKRFFYFSDDAVEAKNLVAYVASEKGSAA---AQRTAAWATQTGKGLLFLTKrAEDKATPAGIFNLSEVSDITKEGSSEFFFKTNGHKHVFQASST 182
                 88************************965544...89******************99****************************************** PP

        PH_6 100 aeRdnWvaqlkek 112
                 aeRd Wva+l +k
  EEA20513.1 183 AERDSWVAALTTK 195
                 ********99875 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 1.8
        PH_6  23 sllks..ekeaesaedaheviawAset 47 
                 + ++     ea++ae + e +a A+et
  EEA20513.1 301 ETAAPaeTTEAPAAEATTEEAAPAAET 327
                 322222223344555556666666665 PP

>> PH  PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1   0.0   3.3e-09     2e-05      12     101 ..     116     193 ..      72     196 .. 0.73

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 3.3e-09
                 SSSSCSEEEEEEEEETTEEEEESSTTCTTESSEEEEEESTTEEEEEEECTTSSSSTSEEEEEESTSSSTEEEEEEESSHHHHHHHHHHHH CS
          PH  12 sgkkkswkkrwfvLkdsellyykndksekdkepkgsislsncevvevvatedpkrkfcfelriverngsrtyllqasseeerkeWikaiq 101
                 s  + +    w++ +++ ll+  ++  e + +p g+++ls++++     t+++  +f f+      ng +++++qass  er +W++a+ 
  EEA20513.1 116 SAAA-QRTAAWATQTGKGLLFLTKR-AEDKATPAGIFNLSEVSDI----TKEGSSEFFFKT-----NG-HKHVFQASSTAERDSWVAALT 193
                 3322.33345555555556666666.99999*************9....669999999999.....88.9******************96 PP

>> PH_4  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   1.6e-05     0.096     156     181 ..     169     194 ..     117     195 .. 0.91
   2 ?   -2.4   0.4      0.59   3.5e+03     127     146 ..     252     268 ..     235     291 .. 0.43
   3 ?   -2.4   0.3       0.6   3.6e+03     132     160 ..     411     439 ..     396     456 .. 0.53

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.6e-05
        PH_4 156 gvsgksivfmarsrqerdlWvlaiaa 181
                 +++g++ vf+a s +erd Wv a+++
  EEA20513.1 169 KTNGHKHVFQASSTAERDSWVAALTT 194
                 678999***************99875 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.59
        PH_4 127 kekkakekasekaeneeknp 146
                 +ekk+++   +++++++k++
  EEA20513.1 252 EEKKDDK---KSRSQSRKRA 268
                 1111111...1222222222 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 0.6
        PH_4 132 kekasekaeneeknpkllksvsrlgvsgk 160
                  e+++ek+e+++ +++ ++  s+lg++ k
  EEA20513.1 411 AEATEEKKEETTPEKRRTSLFSTLGKKVK 439
                 22223333333333344555555555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (533 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1739  (0.0969937); expected 358.6 (0.02)
Passed bias filter:                      534  (0.0297841); expected 358.6 (0.02)
Passed Vit filter:                        90  (0.0050198); expected 17.9 (0.001)
Passed Fwd filter:                        48  (0.00267723); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 1.25u 0.38s 00:00:01.63 Elapsed: 00:00:00.56
# Mc/sec: 2850.98
//
Query:       EEA20514.1  [L=1104]
Description: sulfate transporter family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.4e-61  207.6  25.3    3.7e-61  207.0  25.3    1.3  1  Sulfate_transp  Sulfate permease family
    4.3e-15   55.6   0.0    8.2e-15   54.7   0.0    1.5  1  cNMP_binding    Cyclic nucleotide-binding domain
    2.2e-12   46.6   0.2    4.3e-12   45.7   0.2    1.4  1  STAS            STAS domain
     0.0052   15.9   2.4     0.0095   15.1   2.4    1.3  1  Dicty_CAR       Slime mold cyclic AMP receptor
  ------ inclusion threshold ------
      0.023   14.7   0.9       0.07   13.2   0.9    1.8  1  DUF5389         Family of unknown function (DUF5389)
        5.9    7.0   8.4       0.49   10.5   2.5    2.0  2  SUIM_assoc      Unstructured region C-term to UIM in Ataxin3


Domain annotation for each model (and alignments):
>> Sulfate_transp  Sulfate permease family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  207.0  25.3   1.2e-64   3.7e-61       5     380 .]     301     697 ..     298     697 .. 0.89

  Alignments for each domain:
  == domain 1  score: 207.0 bits;  conditional E-value: 1.2e-64
  Sulfate_transp   5 liaGitvallaiPqalayal.lagl..ppiygL.........yssvvpqlvyalfGtsrqlavGpvavl.....slivgeiiakvaeee....pe 78 
                     l+a+ +++ll+i++al+y++ l++l   +++ L         +s++++ql+++ ++++++  +G+++++       ++  i+++v e++      
      EEA20514.1 301 LPAVFLGLLLNILDALSYGMiLFPLgeAIFSDLgsdgisifyISTIISQLIFSSGASVFKGGIGSEMIEvvpffHKMAFMILNRVGEDNpravLA 395
                     789999**************9****988999**************************************66666668888899996666332233 PP

  Sulfate_transp  79 kgieiattltllaGviqvllGllRLgflveflseavlsGfiaGaaivillsqikvllglervskkeslvsvlsslftnlekvnlakvvlgllllv 173
                     + i   +++++l+Gv+++l+G+++Lg l+ f+++++l+G+i+G++ +++ + ++v+ +l+   + e++ ++l++lf+ l++  l  + ++l l +
      EEA20514.1 396 TTILSFSLSSILTGVVFFLMGVFKLGSLIGFFPRHILIGCIGGVGWFLVATGVEVSARLS--GSLEYNLEMLRHLFQ-LDT--LFLWTVPLALAI 485
                     3334445789*************************************************9..**************7.678..899********* PP

  Sulfate_transp 174 vLlvtkellkklkkllvipapaelvavivatlvsaif...elkreagvki.........vgeipsglpelslpkvdwsllsallpdalaialvgl 256
                     +Llv+k+++k +   +++   +++vav+++++  ++    + +r  g+++              + +    +  v+w++l +++p+++a++++g+
      EEA20514.1 486 ILLVVKRFVKSN---FLVGGYFIVVAVLFYVVKFIARidmHTLRAGGWVFeppaasnpwW----HFYTLYDFDVVNWPALVDTIPAMFALTFFGV 573
                     ********9977...999999998888888765555466677788888855555333321....23677777799******************** PP

  Sulfate_transp 257 le......aiavsksldkkkgykvdsnkELvAlGfsNilsslfgglpatgafsrsavnikaGaktqlsglvsalvvllvllvltplleyiPkavL 345
                     l+      a+ +s + d+     +++++EL+A+G++N+ls+ +g+++++ ++++s+++i++G++++l+g+++a++++ +++v++ ++ yiP+ v+
      EEA20514.1 574 LHvpinvpALGISTGEDN-----LSVDRELIAHGITNTLSGSVGSIQNYLVYTNSLLFINSGGNSRLAGIMLAAATAGIMVVGPVIIGYIPILVV 663
                     ***999999999999999.....************************************************************************ PP

  Sulfate_transp 346 aaiiivagkglLvelkelkklwk.lskldflillat 380
                     +a+i+++g++lL+e  +l+++w  l +l++l+++++
      EEA20514.1 664 GALIFMLGIELLEE--ALVDTWGkLHRLEYLTVVII 697
                     **********9999..******99********9985 PP

>> cNMP_binding  Cyclic nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.7   0.0   2.7e-18   8.2e-15       2      85 ..     988    1069 ..     987    1073 .. 0.94

  Alignments for each domain:
  == domain 1  score: 54.7 bits;  conditional E-value: 2.7e-18
                    EEE-TT-EEE-TTSB-SEEEEEEES-EEEEEEETTS.EEEEEEE-TTEEESHHHHHHTS--SSEEEESSTEEEEEEEHHHHHHH CS
  cNMP_binding    2 rsfkagevifrqGdpadslyivlsGevrvyrlsedgkevvlavlgpGdlfGelalltgeprtatvvAltdsellalprddflel 85  
                    + +++g+v++ +Gd+++ +y+++sG +r     ++g  +  + + +G  +Gel +++g+prtatv +  d++ ++l+r+ + el
    EEA20514.1  988 ETYPKGTVLYYEGDEPTMFYLLESGMLRAEYELPQG--RYSELIVAGRPCGELPFFGGTPRTATVKVDQDCVAWCLDRERWAEL 1069
                    68***************************9999***..578999***********************************99887 PP

>> STAS  STAS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.7   0.2   1.4e-15   4.3e-12      10     117 .]     761     867 ..     752     867 .. 0.91

  Alignments for each domain:
  == domain 1  score: 45.7 bits;  conditional E-value: 1.4e-15
                 EEEEEEEEEESHHHHHHHHHHHHHHHHCCC........-SEEEEEEEEEEEE-HHHHHHHHHHHHHHHHTT-EEEEES..--HHHHHHHHHTTCGGCC. CS
        STAS  10 ililrldgpidfanaesfkeklkravgeepervekkeslkslildlsavsfiDssGvraLkeilkelkrigvevvlvn..ikpevreklektgffdeve 106
                  li++l+g ++f+++  ++   +  ++ee+    +++++++l+ld+s v+ +D s+++aL +i + l +++v+v++++  +++ev + l+++g+f +++
  EEA20514.1 761 TLIIKLSGFLFFGTIVNVETTARGLIDEEA---FTRQPIRFLVLDFSRVNGLDFSAAEALTRINRILGKRNVQVLISGldVQGEVGKSLQNVGLFADES 856
                 58************9999999999999997...4789****************************************93346888899*********** PP

                 .SEEESSHHHH CS
        STAS 107 eeklfltvhdA 117
                 + ++f+++++A
  EEA20514.1 857 QVQIFEDLNSA 867
                 *****999887 PP

>> Dicty_CAR  Slime mold cyclic AMP receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   2.4   3.2e-06    0.0095      12     146 ..     397     530 ..     387     555 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 3.2e-06
   Dicty_CAR  12 svllladfssil.gcllvligfwrlkllrnhitkvialfcatsllkdlistiltlleeaqesgfqcylyaivitygslacwlwtlclalsiynlivkre 109
                 ++l +  +ssil g++  l+g ++l  l     + i + c+  +   l++t + ++  + +++++  l  +   +   + +lwt+ lal+i +l+vkr 
  EEA20514.1 397 TILSF-SLSSILtGVVFFLMGVFKLGSLIGFFPRHILIGCIGGVGWFLVATGVEVS-ARLSGSLEYNLEMLRHLFQLDTLFLWTVPLALAIILLVVKRF 493
                 44444.466665388899*********************************99876.56789999999999999999999******************* PP

   Dicty_CAR 110 pepekfekyyfvlcwglplistivmlskkvievvgnw 146
                  + + +   yf+++ +l +++  +          g+w
  EEA20514.1 494 VKSNFLVGGYFIVVAVLFYVVKFIARIDMHTLRAGGW 530
                 ****999999988877766665554333333334555 PP

>> DUF5389  Family of unknown function (DUF5389)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.9   2.3e-05      0.07      31      97 ..     452     517 ..     440     523 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 2.3e-05
     DUF5389  31 llispnllknPalsdtqvklmsiflwlyPlvlaiiarilyklnqrkaklakklllisavifygvlly 97 
                   +s +l+ n ++  +  +l ++flw+ Pl+laii  ++ ++ + +  l    +++ av+fy v ++
  EEA20514.1 452 ARLSGSLEYNLEMLRHLFQLDTLFLWTVPLALAIILLVVKRFVKSNF-LVGGYFIVVAVLFYVVKFI 517
                 5678899999999999999999*************999888877665.5556678889****87654 PP

>> SUIM_assoc  Unstructured region C-term to UIM in Ataxin3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.4      0.72   2.2e+03      50      64 .]     191     205 ..     185     205 .. 0.78
   2 ?   10.5   2.5   0.00016      0.49      22      41 ..     882     898 ..     869     918 .. 0.64

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.72
  SUIM_assoc  50 prekpttSsgalgrD 64 
                 ++++p tSs++ + D
  EEA20514.1 191 IENRPETSSSGNDTD 205
                 678999999987776 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00016
  SUIM_assoc  22 rreaYFEKqeqqqqqqqqqq 41 
                 r+ea  E+   qqqqqqqqq
  EEA20514.1 882 RKEALTEQ---QQQQQQQQQ 898
                 77777776...333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1104 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       892  (0.0497518); expected 358.6 (0.02)
Passed bias filter:                      475  (0.0264934); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.87u 0.31s 00:00:01.18 Elapsed: 00:00:00.50
# Mc/sec: 6618.27
//
Query:       EEA20515.1  [L=237]
Description: PSF1 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      3e-14   53.4   0.1    5.5e-14   52.6   0.1    1.5  1  Sld5      GINS complex protein


Domain annotation for each model (and alignments):
>> Sld5  GINS complex protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.6   0.1     3e-18   5.5e-14       2      94 ..      21     127 ..      20     157 .. 0.86

  Alignments for each domain:
  == domain 1  score: 52.6 bits;  conditional E-value: 3e-18
                 EEEHHHHHHHHHTTSCCCHHCHHHCHHHHHHCCCHHTTS...SSSTTTTTTHHHHHHHHHHHHT.HCHHHHHHHHHHHHHHHHHHHTHCHHHHHH.... CS
        Sld5   2 eLPlWlaelLkrqrrveieppewlspesleailedetks...sdlpslpphflelavkllelardldelkrllrdllevRlakirkfaenledaa.... 93 
                 +LP++++e++ r++ +e+++ ++  ++ l+ + +++ +     +++++p   + l v +l+++r+    kr+l+++++vR++k+++++++ +d +    
  EEA20515.1  21 HLPPYQTEIV-RSVAREVRDLNNDVAHHLAPFESADGSQqssFNPSAQPAIACALLVDHLCMRRN----KRCLLAYHRVRAEKLEEMCWKGIDVLeqqq 114
                 8*********.9************99999999999999888889999******************....************************998888 PP

                 ............H CS
        Sld5  94 ............g 94 
                             +
  EEA20515.1 115 pvttaagnnnnnN 127
                 8887766554430 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (237 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       814  (0.0454013); expected 358.6 (0.02)
Passed bias filter:                      524  (0.0292264); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 1741.70
//
Query:       EEA20516.1  [L=513]
Description: HMG box protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.9e-10   38.7   1.0    1.8e-09   37.9   1.0    1.4  1  HMG_box          HMG (high mobility group) box
  ------ inclusion threshold ------
      0.058   12.7   0.0       0.11   11.8   0.0    1.4  1  MATalpha_HMGbox  Mating-type protein MAT alpha 1 HMG-box
        6.2    7.9  11.8       0.44   11.5   3.6    3.1  3  Pap_E4           E4 protein


Domain annotation for each model (and alignments):
>> HMG_box  HMG (high mobility group) box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.9   1.0     3e-13   1.8e-09       2      69 .]     161     228 ..     160     228 .. 0.96

  Alignments for each domain:
  == domain 1  score: 37.9 bits;  conditional E-value: 3e-13
                 -SS--HHHHHHHHHHHHHHHHSTTS-HHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
     HMG_box   2 kRplsafflfskeqraklkaenPelknaeiskklgekWkalseeeKkkYeekaekekaryekekpeyk 69 
                  Rp+++f++++++  +  k+ + +++ + +s  +g  W ++++e ++kYe  a  e+  ++k++peyk
  EEA20516.1 161 ARPMNSFMMYRSAYAERAKEWCKQNNHQVVSCLAGTSWPMEPPEIREKYELLALVERDNHQKAHPEYK 228
                 6**************99999999999999999***********************************8 PP

>> MATalpha_HMGbox  Mating-type protein MAT alpha 1 HMG-box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   1.8e-05      0.11      34      90 ..     146     213 ..     116     218 .. 0.65

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 1.8e-05
  MATalpha_HMGbox  34 e.....sreakakkakkklNgFmgfRsYylkLfsdlqqke....aSgfltqlWekdp..frnkWdlia 90 
                      +        +k+ k  +++N Fm +Rs y +  +++ +++     S + ++ W  +p   r+k++l+a
       EEA20516.1 146 TgdirrRDAKKSGKIARPMNSFMMYRSAYAERAKEWCKQNnhqvVSCLAGTSWPMEPpeIREKYELLA 213
                      23333223455667789************777777554441222577788889999523578888877 PP

>> Pap_E4  E4 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.2       0.5     3e+03      36      63 ..     101     126 ..      90     144 .. 0.58
   2 ?   -0.7   0.1      0.48   2.9e+03      24      80 ..     133     192 ..     121     197 .. 0.64
   3 ?   11.5   3.6   7.4e-05      0.44       8      58 ..     207     258 ..     200     300 .. 0.67

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.5
      Pap_E4  36 rkkkrrrlssdsdsssstspsspttkks 63 
                 ++  rrr++++++  + ++ + p+  ++
  EEA20516.1 101 PR-VRRRHKTAKG-DKASKIEIPAPLSQ 126
                 23.5666666666.45555665544444 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.48
      Pap_E4  24 prrppkprpwaprk.kkrrrlssdsdsssstspsspttkks..eeespwtvtttgssvtl 80 
                 + ++     w  r    rrr  ++s++  ++ +s    ++   e++++w  + ++++v+ 
  EEA20516.1 133 HVPIKDMEAWVNRTgDIRRRDAKKSGKIARPMNSFMMYRSAyaERAKEWCKQNNHQVVSC 192
                 445555557888887777887788876666665555555445788888888888888765 PP

  == domain 3  score: 11.5 bits;  conditional E-value: 7.4e-05
      Pap_E4   8 ekYPLLdLltt.y..pttPprrppkprpwaprkkkrrrlssdsdsssstspssp 58 
                 ekY LL L++  +  +++P+ +  ++++++p++k+r ++++ sd   + s s  
  EEA20516.1 207 EKYELLALVERdNhqKAHPEYKFAPNKTQTPPRKRRANNDNGSD--ADDSASRI 258
                 8********99445555688888888888888834433334444..22222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (513 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       599  (0.0334096); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.39
# Mc/sec: 3946.23
//
Query:       EEA20517.1  [L=831]
Description: PHD finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.5e-07   30.0  13.2      8e-07   28.9  13.2    1.7  1  PHD       PHD-finger
  ------ inclusion threshold ------
       0.24   11.0  12.4      0.076   12.6   8.7    2.0  2  PHD_2     PHD-finger


Domain annotation for each model (and alignments):
>> PHD  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.9  13.2     9e-11     8e-07       2      51 ..     437     489 ..     436     490 .. 0.90

  Alignments for each domain:
  == domain 1  score: 28.9 bits;  conditional E-value: 9e-11
                 BTTTTS...TTSTTSCEEEETTTSCEEETTTSSSTHSHHSHHSSTBSSTTTHT CS
         PHD   2 CavCkk...ksdeeeelvqCdgCkrwfHqkClkppleseekpegewlCekCke 51 
                 C+ C+    + d++++ v C++C+ w+H kCl+++++++ek++ +++C  Ck+
  EEA20517.1 437 CSGCGVhgeNIDDGSHCVACERCNVWQHSKCLGISQQDAEKDDFHFVCADCKR 489
                 77787766688889***********************9999999*******97 PP

>> PHD_2  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1      0.19   1.7e+03       7      12 ..     437     442 ..     428     443 .. 0.72
   2 ?   12.6   8.7   8.5e-06     0.076       4      36 .]     453     488 ..     451     488 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.19
       PHD_2   7 CdkCsv 12 
                 C++C v
  EEA20517.1 437 CSGCGV 442
                 888877 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 8.5e-06
       PHD_2   4 llsCdkCsvaVHasCYGvskesdgee...WlCrrCe 36 
                  + C +C+v  H +C G+s+++++++   ++C+ C+
  EEA20517.1 453 CVACERCNVWQHSKCLGISQQDAEKDdfhFVCADCK 488
                 689*******************9998999******5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (831 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2296  (0.128061); expected 358.6 (0.02)
Passed bias filter:                      622  (0.0346924); expected 358.6 (0.02)
Passed Vit filter:                        95  (0.00529868); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.94u 0.31s 00:00:01.25 Elapsed: 00:00:00.47
# Mc/sec: 5315.47
//
Query:       EEA20518.1  [L=395]
Description: cell differentiation protein (Rcd1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   2.6e-126  420.2   3.2   3.2e-126  419.9   3.2    1.1  1  Rcd1            Cell differentiation family, Rcd1-like
      0.004   17.0   6.2     0.0062   16.3   6.2    1.3  1  TAF4            Transcription initiation factor TFIID compone
  ------ inclusion threshold ------
      0.077   13.2  11.2       0.62   10.3   7.8    2.5  2  baeRF_family10  Bacterial archaeo-eukaryotic release factor f
       0.64   10.4   2.9       0.93    9.9   2.9    1.2  1  EPL1            Enhancer of polycomb-like
       0.85    9.9   4.6        1.2    9.5   0.0    2.5  2  CnrY            Anti-sigma factor CnrY
       0.87    9.7   5.1        2.3    8.3   4.5    1.8  2  Spond_N         Spondin_N
        3.9    7.4  16.8        4.8    7.1  16.8    1.1  1  TFIIA           Transcription factor IIA, alpha/beta subunit


Domain annotation for each model (and alignments):
>> Rcd1  Cell differentiation family, Rcd1-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  419.9   3.2  1.3e-129  3.2e-126       1     259 []     123     381 ..     123     381 .. 0.99

  Alignments for each domain:
  == domain 1  score: 419.9 bits;  conditional E-value: 1.3e-129
        Rcd1   1 lildlakpekreeaLleLskkresvedlallLwesfgtvaaLLqeivsiYpllspptltaaesnrvcnaLallqcvashpetrklflkakiplyLypfL 99 
                 ++ +l +p++re+aL eLskkre+v++lal++w+sfg+++aLLqei+s+Ypll+p++ltaa+snrvcnaLallqcvash++tr+lfl+a+ipl+LypfL
  EEA20518.1 123 WVAELLDPNRRETALMELSKKREQVPELALVIWHSFGVMTALLQEIISVYPLLNPSQLTAAASNRVCNALALLQCVASHNDTRTLFLNAHIPLFLYPFL 221
                 899************************************************************************************************ PP

        Rcd1 100 nttsksrefEylRltsLgvigaLvktddkevikflldteivplclrimesGselsktvAtfIlqkiLlddeGLeYicqtaerfsavaevLnkmvvslte 198
                 nttsksr+fEylRltsLgvigaLvk+d+++vi+fll+tei+plclrime+GselsktvA+fI+qkiLldd GL+Yic+t+erf+av +vL++mv++l+e
  EEA20518.1 222 NTTSKSRPFEYLRLTSLGVIGALVKNDSSDVINFLLTTEIIPLCLRIMETGSELSKTVAIFIVQKILLDDLGLNYICATYERFYAVGTVLSNMVTQLVE 320
                 *************************************************************************************************** PP

        Rcd1 199 epssrllkhvircYlrLsdnprareaLkkclpelLkdktfkellkedpetkkwlkqLlenl 259
                 ++++rllkhv+rc+lrLsdn+rareaL++clpe L+d tf+++l++d +tk++l qLl nl
  EEA20518.1 321 QQTVRLLKHVVRCFLRLSDNSRAREALRQCLPEPLRDATFSSVLRDDAATKRCLAQLLINL 381
                 **********************************************************886 PP

>> TAF4  Transcription initiation factor TFIID component TAF4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   6.2   2.4e-06    0.0062     157     227 ..      27      98 ..      10     139 .. 0.61

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 2.4e-06
        TAF4 157 eeekklkaketakevqkeedekarhraANatAlaavgeprkKkysw..msagsgsgggksgaskssssggkgl 227
                 ++++  +a+  ++++q    ++++h +A a+A+aa+  ++++ y    m  gsgsg+g++ + +++++ g ++
  EEA20518.1  27 QQQQHHQAQHHQQQQQHSSLAAQQHAQAAAAAAAAAA-AQQQHYNRiaMAGGSGSGAGNQAQGSGNNAAGLNA 98 
                 3444444444455666888888999999888888888.77777744224444445555555444444444433 PP

>> baeRF_family10  Bacterial archaeo-eukaryotic release factor family 10
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   7.8   0.00024      0.62      47      97 ..      27      77 ..       2      82 .. 0.64
   2 ?    3.6   0.1     0.028        73      97     124 ..     339     366 ..     312     378 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00024
  baeRF_family10 47 pgrtktggwksqdrfqrreeeqaerhlkevAellakl.leergverlvlgGd 97
                    +++++++++  ++++q+++   a++h++++A+++a++ ++++++ r+ ++G+
      EEA20518.1 27 QQQQHHQAQ-HHQQQQQHSSLAAQQHAQAAAAAAAAAaAQQQHYNRIAMAGG 77
                    223344444.666666677777777777666666555055566*****9997 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.028
  baeRF_family10  97 d.eeetaalldrlpkalrarvvgtlplpv 124
                     d  ++++al+++lp++lr+ ++ + +l +
      EEA20518.1 339 DnSRAREALRQCLPEPLRDATFSS-VLRD 366
                     447899************998877.4444 PP

>> EPL1  Enhancer of polycomb-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   2.9   0.00036      0.93      29      74 ..      22      69 ..       4     157 .. 0.62

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00036
        EPL1 29 eeiseknsnkensqqavetgvdkkeenekh.q.viaaakkkesssass 74
                +  ++++++++++q++++++++++ + ++h q + aaa ++++++++ 
  EEA20518.1 22 SWLHQQQQQHHQAQHHQQQQQHSSLAAQQHaQaAAAAAAAAAAQQQHY 69
                233344444444456666666666566888774444444444433333 PP

>> CnrY  Anti-sigma factor CnrY
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   1.9      0.37   9.5e+02      37      59 ..      43      65 ..      31      75 .. 0.70
   2 ?    9.5   0.0   0.00045       1.2      46      91 ..     183     232 ..     153     235 .. 0.71

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.37
                XXXXXXXXXXXXXXXXXXXXXXX CS
        CnrY 37 qivlvarrdaqraivcaalaalv 59
                +  l+a+++aq a   aa aa+ 
  EEA20518.1 43 HSSLAAQQHAQAAAAAAAAAAAQ 65
                56789999999888777777664 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00045
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....XXXXXXXXXXXX CS
        CnrY  46 aqraivcaalaalvafvainrvatlmlekaaptw....laspsaaspysl 91 
                 a    vc ala l   ++ n + tl l+   p++    l + s + p+  
  EEA20518.1 183 AASNRVCNALALLQCVASHNDTRTLFLNAHIPLFlypfLNTTSKSRPFEY 232
                 455679**********************9999862222578888888875 PP

>> Spond_N  Spondin_N
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   4.5   0.00089       2.3      15      85 ..      11      78 ..       3     110 .. 0.76
   2 ?   -1.4   0.0      0.84   2.1e+03      40      66 ..     303     329 ..     299     342 .. 0.85

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00089
     Spond_N 15 tfpkdyPewrpqwskliGasHsseytlyeygkvasegvksvaeagkakklekelkeekkkvkkvfkapgis 85
                ++ ++yP+ +p w +   ++H+++ +  ++++ +s + ++ a+a++a +  + ++++    ++ + ++g s
  EEA20518.1 11 SHQHQYPQAEPSWLHQQQQQHHQAQHHQQQQQHSSLAAQQHAQAAAAAAAAAAAQQQ---HYNRIAMAGGS 78
                4899****************************************9999988888774...33333344333 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.84
     Spond_N  40 tlyeygkvasegvksvaeagkakklek 66 
                 ++y  g+v s+ v +++e+ + + l++
  EEA20518.1 303 RFYAVGTVLSNMVTQLVEQQTVRLLKH 329
                 689999***********9988877765 PP

>> TFIIA  Transcription factor IIA, alpha/beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1  16.8    0.0019       4.8     172     232 ..      13      73 ..       1     149 [. 0.39

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0019
       TFIIA 172 qssvaalqaqsqqaqalaepqqqlekqqqqqqqqqqqqqqq.qvqqqqqe......esqqaqqasqe.....q 232
                 q++ ++ +++         +qqq+  ++q q++qqqqq+++ ++qq+ q+        ++aqq   +     +
  EEA20518.1  13 QHQYPQAEPS------WLHQQQQQ--HHQAQHHQQQQQHSSlAAQQHAQAaaaaaaA-AAAQQ---QhynriA 73 
                 1111111111......11111111..1111222222222221222222222222211.11111...1112231 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (395 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2897  (0.161582); expected 358.6 (0.02)
Passed bias filter:                     1171  (0.0653132); expected 358.6 (0.02)
Passed Vit filter:                       164  (0.00914719); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.74u 0.36s 00:00:01.10 Elapsed: 00:00:00.47
# Mc/sec: 2544.86
//
Query:       EEA20519.1  [L=363]
Description: hypothetical protein PMAA_043530 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    0.00062   20.2   0.1    0.00062   20.2   0.1    2.4  2  CYYR1            Cysteine and tyrosine-rich protein 1
      0.009   16.2   1.4      0.015   15.6   0.7    1.8  1  Glycophorin_A    Glycophorin A
  ------ inclusion threshold ------
      0.018   15.5   1.1        1.2    9.6   0.0    2.7  2  DUF202           Domain of unknown function (DUF202)
       0.11   13.4   0.0         21    6.1   0.0    2.7  2  EphA2_TM         Ephrin type-A receptor 2 transmembrane domai


Domain annotation for each model (and alignments):
>> CYYR1  Cysteine and tyrosine-rich protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   1.3       1.6   7.3e+03      27      34 ..     121     128 ..      83     154 .. 0.62
   2 !   20.2   0.1   1.4e-07   0.00062      51      82 ..     199     228 ..     193     270 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1.6
       CYYR1  27 dckeyccd 34 
                  c + cc 
  EEA20519.1 121 TCGTSCCS 128
                 23333332 PP

  == domain 2  score: 20.2 bits;  conditional E-value: 1.4e-07
       CYYR1  51 lsgtaiagivfgvvflmgvvagialcvcmcvk 82 
                 lsg aiagiv+gvv   gv   i+lc c+c++
  EEA20519.1 199 LSGGAIAGIVIGVV--AGVFLLILLCACLCIR 228
                 8***********98..69************97 PP

>> Glycophorin_A  Glycophorin A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.7   3.2e-06     0.015      21      83 ..     163     228 ..     132     232 .. 0.60

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 3.2e-06
                    XXXXXXXXXXXXXXXXXXXXXXXX...XXXXSSSSSSS-TTHHHHHHHHHHHHHHHHHHHH.HHHH CS
  Glycophorin_A  21 astpsahevseltirtevaaeqeet..gereqlvhdFselvitliifgvmAgvigtillis.Ylir 83 
                    a t +a++++ +t+    ++  + t   +  +     s   i++i++gv+Agv + ill +  +ir
     EEA20519.1 163 AETVTATQSATTTVGFIAPVSTNGTtvITGAPHSGGLSGGAIAGIVIGVVAGVFLLILLCAcLCIR 228
                    3333333333333333333333333222223344578999******************98724666 PP

>> DUF202  Domain of unknown function (DUF202)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   1.5     0.038   1.7e+02      33      57 ..     195     219 ..     162     228 .. 0.64
   2 ?    9.6   0.0   0.00026       1.2      40      64 ..     290     315 ..     234     319 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.038
      DUF202  33 tgepsalgkilglilivlgiltllv 57 
                 +++  ++g+i+g+++ v++ ++ll+
  EEA20519.1 195 HSGGLSGGAIAGIVIGVVAGVFLLI 219
                 3444445899998855555444443 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00026
      DUF202  40 g.kilglilivlgiltllvglvrylr 64 
                 g  +lg+++i++g+++l++gl+r + 
  EEA20519.1 290 GlGWLGWFAIIAGAVALCLGLRRRRN 315
                 33799*****************9876 PP

>> EphA2_TM  Ephrin type-A receptor 2 transmembrane domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.1     0.015        69       1      21 [.     207     226 ..     203     265 .. 0.73
   2 ?    6.1   0.0    0.0047        21       9      38 ..     297     340 ..     291     361 .. 0.51

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.015
    EphA2_TM   1 iiaaavaglvllvilvilvlv 21 
                 i++++vag++ll++ +  +l+
  EEA20519.1 207 IVIGVVAGVFLLIL-LCACLC 226
                 33344444444333.333333 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.0047
    EphA2_TM   9 lvllvilvilvlvlvrrrsknrkqksdl.......k.......s 38 
                 + ++  +v+l+l l+rrr++++k++ +                s
  EEA20519.1 297 FAIIAGAVALCLGLRRRRNEEEKSEYSYgpgssyyYysdyysgS 340
                 45555666666666655555555555446554444043333331 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (363 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1067  (0.0595125); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 2508.98
//
Query:       EEA20520.1  [L=609]
Description: autophagy related lipase Atg15, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.1e-06   28.6   0.0    2.7e-06   27.3   0.0    1.6  1  Lipase_3     Lipase (class 3)
  ------ inclusion threshold ------
      0.074   12.3   0.0       0.12   11.6   0.0    1.2  1  Hydrolase_4  Serine aminopeptidase, S33


Domain annotation for each model (and alignments):
>> Lipase_3  Lipase (class 3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.0     3e-10   2.7e-06      45      84 ..     290     329 ..     240     338 .. 0.82

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 3e-10
                 S-HHHHHHHHHHHHHHHTT-EEEEEEEETHHHHHHHHHHH CS
    Lipase_3  45 eslreqvlkelkrllekypeysivvtGHSLGgalAlLaal 84 
                    +e+ l+   ++ + yp++++++tGHSLGga+++L++l
  EEA20520.1 290 DRYYESALDLYTNITHLYPNANVWLTGHSLGGAMSALLGL 329
                 45666777777789999********************987 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   1.4e-05      0.12      55      94 ..     289     328 ..     284     334 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 1.4e-05
  Hydrolase_4  55 fddyvdDlaafvekvkeehpelplfllGhSmGGliallyl 94 
                   d+y++ +  +++++   +p++++ l GhS+GG++++l++
   EEA20520.1 289 KDRYYESALDLYTNITHLYPNANVWLTGHSLGGAMSALLG 328
                  5677788888889999999****************99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (609 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       643  (0.0358637); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.47
# Mc/sec: 3865.27
//
Query:       EEA20521.1  [L=499]
Description: cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.5e-40  137.8   0.0    6.1e-40  137.3   0.0    1.3  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.3   0.0   3.4e-44   6.1e-40     261     458 ..     277     489 ..     124     494 .. 0.81

  Alignments for each domain:
  == domain 1  score: 137.3 bits;  conditional E-value: 3.4e-44
                 HHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHCCTTT..T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEETT CS
        p450 261 eelaatvlellf...aGvdTtsstlswaLyeLaknPevqeklreEidevlgdkr..eptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirg 354
                 ++l+ ++ + l+   a+++Tt + ls aL+ La +Pe+q+ lreE+++vl+       t + l+kl  ld ++kE++R+ p+  l+ +R+v++d+++++
  EEA20521.1 277 HNLKYQAHNQLIasaAAIHTTNMQLSHALFDLAAYPEYQAPLREEVQTVLRTEPngVWTKSGLAKLRKLDSFLKESQRMNPLGLLTFERRVMNDITLPD 375
                 455555555554111679********************************54334599***************************************** PP

                 .EEE-TT-EEEEEHHHHHT-TTTSSSTTS--GGGGB-TTS........CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGG CS
        p450 355 .ylipkGtevivnlyalhrdpevfpnPeeFdpeRFldekg........nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdpp 444
                  ++ipkG+++  +++++ +d ++++nP++F   RF++ ++        ++      +l FG G+++C+G+ lA  e+kl+l++l+ +++ +l+++t+ p
  EEA20521.1 376 gVTIPKGYNIGCPTSSIAKDSALWDNPNTFEAFRFERLRQqpgcenkhQFVTTGIDSLYFGHGKHACPGRFLADAEIKLILINLILHYDCKLPDGTSRP 474
                 *************************************9999997766655556667888*********************************9999999 PP

                 EEESSC.SSEEESSS CS
        p450 445 pileks.glllppkp 458
                  + e + g++  p +
  EEA20521.1 475 ANVEMNsGVMADPTK 489
                 888887666665555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (499 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       506  (0.0282224); expected 358.6 (0.02)
Passed bias filter:                      488  (0.0272185); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.25s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 3480.07
//
Query:       EEA20522.1  [L=423]
Description: toxin biosynthesis protein (Tri7), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.9e-22   78.7   1.2    2.9e-22   78.7   1.2    1.9  2  MBOAT_2   Membrane bound O-acyl transferase family


Domain annotation for each model (and alignments):
>> MBOAT_2  Membrane bound O-acyl transferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.1       0.6   1.1e+04      46      59 ..     234     247 ..     218     247 .. 0.66
   2 !   78.7   1.2   1.6e-26   2.9e-22       1      82 [.     256     343 ..     256     344 .. 0.90

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 0.6
     MBOAT_2  46 larylqllvaFllS 59 
                 l+ + +ll aF++S
  EEA20522.1 234 LNAISHLLGAFFVS 247
                 45566777888877 PP

  == domain 2  score: 78.7 bits;  conditional E-value: 1.6e-26
     MBOAT_2   1 wpplfgslleayslrrfWgrfWHqlfrrglkstakkilrlllg..sk..larylqllvaFllSGllHaagdytqlap..estallfFl 82 
                 w+plfg+++e yslr+fWg+fWHq +rr+++++++++++++l+  +k  ++ryl+++++F lSG+ Ha++d+    +  e++++ fFl
  EEA20522.1 256 WRPLFGRVSEIYSLRQFWGTFWHQNLRRMISEPVEFLAHKVLRlpKKgiVQRYLKIVLSFYLSGITHAVADISSTLSwgEQLTVEFFL 343
                 9*******************************99999999998874467***********************9999766666888886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (423 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       530  (0.029561); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.48
# Mc/sec: 2630.90
//
Query:       EEA20523.1  [L=550]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-39  136.4  51.1      4e-39  134.5  49.0    2.8  2  MFS_1     Major Facilitator Superfamily
     0.0024   16.2   2.8     0.0024   16.2   2.8    2.4  2  OATP      Organic Anion Transporter Polypeptide (OATP) family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  134.5  49.0   4.4e-43     4e-39       1     352 [.      42     441 ..      42     442 .. 0.90
   2 ?    0.7   0.0     0.022     2e+02     222     259 ..     474     514 ..     443     536 .. 0.48

  Alignments for each domain:
  == domain 1  score: 134.5 bits;  conditional E-value: 4.4e-43
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlga 99 
                 l+l+ +++al+ +++++a+p  ++++++ s    g+  ++y l+ +++++ +G + + f  +++++++ll+f lg++l++ a s+++l+v+r+++G+ga
  EEA20523.1  42 LCLGMLVVALDNTVIATAIP-RITTEFH-SLGDTGWYGSAYLLTNCALQPTFGKVYTVFNVKWTYITALLIFELGSILCAAAKSSTMLIVGRAVAGAGA 138
                 68999***************.*******.**********************************************55555346666************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 +alf++++ +i   +p ++r+ +ig+l+++f++++++gpl+gg+l++++ Wr++f +  + + +a v+  +++  ++++ +++s ++++          
  EEA20523.1 139 AALFSGAMNIIGSSVPLRKRPVYIGILGSMFGIASVVGPLIGGALTEYVTWRWCFCLPIGGLTVATVV--IFFSSPAKQTPKQSLVQKLrgldaagavl 235
                 *****************************************************************997..89988888888888888889********* PP

       MFS_1 189 ............................................kgtgpaplvpawkallkdpvlw.illialllfffgfsglltllplylqevlglsg 242
                                                             +  g ++ +p    +lk++ +w ++++ ++l+ +g+++l ++lp+y+q v+  s 
  EEA20523.1 236 lisaiiclllalqwggttyswsdskvfgcligfgllliafsvlqVYLGDHGTLP--PRILKQRTVWsVCWFEFVLG-LGLYTLIYYLPFYFQAVRFTS- 330
                 ******************999999999999999988888888886666666666..78888888997777777777.5************66666666. PP

       MFS_1 243 lllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllll.vlvliGfglgfvfpsllalasdlappeeagtasgl 340
                 + ++g+ +  l + + i+++++g + + +g+  + l+  ++l+++a+gl+++  t+s++  ++   +l+G+g g+     +++++ ++pp  +   ++l
  EEA20523.1 331 AESSGIRMIPLLVSITIASIVGGSVTTITGHYVAFLWLSGGLFTIAAGLCYTLETNSYAGKWIgYQLLAGIGCGLSLQVPFVATQVVLPPADQPIGNSL 429
                 68888888777777788899***********************************99999999545558889999999999999999999********* PP

       MFS_1 341 fntagslggalg 352
                 + ++ slggal+
  EEA20523.1 430 VVFFTSLGGALA 441
                 **********98 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.022
       MFS_1 222 gfsglltllplylqevlgls.........glllaglllallalvgai 259
                 g +g+ +++p+  + v + s         + ++++  +a++++++ i
  EEA20523.1 474 GATGIKATTPS--NLVQDVSesynyaitrA-FILA--IAAGGIAF-I 514
                 33334444444..33333332222212111.1111..11111111.1 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   2.8   2.7e-07    0.0024     131     239 ..     123     219 ..      42     233 .. 0.83
   2 ?   -2.0   3.9     0.092   8.2e+02     289     323 ..     291     325 ..     250     396 .. 0.60

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 2.7e-07
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 131 lvllfflaqlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllklyvdidseisltpkdprWvgaWWlgflilgvlllla 229
                   ++++++  ++G+Ga+++++ ++  i  +v  ++ p+y+gil ++  +  ++G l+G++l++ yv++           rW     +g l ++++++++
  EEA20523.1 123 SSTMLIVGRAVAGAGAAALFSGAMNIIGSSVPLRKRPVYIGILGSMFGIASVVGPLIGGALTE-YVTW-----------RWCFCLPIGGLTVATVVIFF 209
                 23589******************************************************8877.8888...........66666666666666666666 PP

                 xxxxxxxxxx RF
        OATP 230 aiplffFPke 239
                 + p    Pk+
  EEA20523.1 210 SSPAKQTPKQ 219
                 6665555555 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.092
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 289 rllknpifllvilssvfeillvaGfitFlpkylEt 323
                 r+lk+++ + v+  + +  l++  +i +lp y + 
  EEA20523.1 291 RILKQRTVWSVCWFEFVLGLGLYTLIYYLPFYFQA 325
                 45555555666666666666666666666666554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (550 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       631  (0.0351944); expected 358.6 (0.02)
Passed bias filter:                      271  (0.0151152); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.31s 00:00:00.93 Elapsed: 00:00:00.47
# Mc/sec: 3520.02
//
Query:       EEA20524.1  [L=499]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-33  116.4  39.7    1.3e-33  116.4  39.7    1.8  2  MFS_1     Major Facilitator Superfamily
    1.5e-10   40.5   4.4    1.5e-10   40.5   4.4    2.7  3  Sugar_tr  Sugar (and other) transporter
    2.9e-06   26.0   5.0    4.6e-06   25.3   5.0    1.2  1  TRI12     Fungal trichothecene efflux pump (TRI12)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.4  39.7   2.2e-37   1.3e-33       2     352 ..      69     448 ..      68     449 .. 0.79
   2 ?    1.7   8.9     0.016        98      94     172 ..     406     483 ..     406     496 .. 0.82

  Alignments for each domain:
  == domain 1  score: 116.4 bits;  conditional E-value: 2.2e-37
       MFS_1   2 llaaflsalarsilgpalplalaedlgispse.igllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlga 99 
                 ++++f++ ++ ++l++a+p  + +++  + ++ +++ +++yalg av+ l++++ls+ +Gr  ++ ++++lf++++++++++++l +l+++ ++qG ++
  EEA20524.1  69 AVMTFITPMSPAMLSSAIP-EILTEFPTTNTVlASMSVSIYALGLAVGPLIIAPLSEAYGRLVLYHATAILFIIFSIACAVSTNLNMLIAFEFFQGCMG 166
                 6899***************.56677777777658889999***********************************66666446666************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllll.peepperkrkspkeee......... 188
                 +a +++g+  +ad++++eerg  i++l++g  ++  +gp+ g++la++ gWr+vf++++i++ +  + ++++l  e++ +    ++ + +         
  EEA20524.1 167 SAPITMGGGSVADMYSREERGARIAFLATGPLIAQFVGPVGGSFLAAARGWRWVFWLVTILTGVIEI-GYCFLmHETYQPVLLRRKLRGLrqagntqis 264
                 ****************************************************************966.4555524444444444444444777777778 PP

       MFS_1 189 .........kgtgpaplvpawkallkdpvlwillialllfffgfsg.lltllplylqevlgls....glllaglllallalvgailallagrlsdr... 270
                            +g + l+ ++k+l+  p ++ l ++++++ + f++ ++tl  ++   ++gl     gl+++g  +a ++++g   a  ++ +sdr   
  EEA20524.1 265 dfgpdesplRLVGSSILR-PLKMLFLFPIIFGLGTHAAVGYAYFYLlITTLANIF-IGTYGLEpkivGLVYLG--IATGMALG---AATFAIYSDRmik 356
                 866666663333333333.477777777665344444444333333577777777.*******7777666666..44444444...5556666666555 PP

       MFS_1 271 .......lgrrrrlllallllllaalglallavtssavllllvlvl.iGf.glgfv..fpsllalasdlappeeagtasglfntagslggalg 352
                         +++ rl+ ++++++++  gl++ ++t  + ++++v ++  Gf glg++    s+ ++++d +p  +a++ +g++++++s+ +a+ 
  EEA20524.1 357 qraahrmAKPEDRLVPMVAGGVAIPTGLLIYGWTAQYGVHWIVPIIgTGFlGLGLMwlLLSIDTYLVDAYP-LYAASSIGATTVFRSFISAFL 448
                 5666667888********************************88888999999999667889999999997.99999******9999877765 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.016
       MFS_1  94 lqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllll 172
                 + Glg  +l+ ++ ++++d +p    ++ ig  +++ s+ +++ pl+g+ +++ lg  +   +la++++ ++ + ll+l
  EEA20524.1 406 FLGLGLMWLLLSIDTYLVDAYPL-YAASSIGATTVFRSFISAFLPLAGPSMYARLGLGWGNSLLAFIAIALVPIPLLFL 483
                 67999999999************.********************************66666666666665544444554 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.5   4.4   2.6e-14   1.5e-10      21     191 ..      18     238 ..      15     244 .. 0.84
   2 ?   -3.4   1.8      0.53   3.2e+03      85     121 ..     308     343 ..     286     353 .. 0.56
   3 ?    0.4   0.6     0.039   2.3e+02     322     372 ..     404     456 ..     400     459 .. 0.84

  Alignments for each domain:
  == domain 1  score: 40.5 bits;  conditional E-value: 2.6e-14
                 GTHHHHHHHHTSTT--SHHHHHH...........................................................HHHHHHHTHHHHHHHHH CS
    Sugar_tr  21 afltllkfaknfglsksksskee........................................................ssvlsglivsiflvGaiiGs 63 
                 a+++++++ +n  ++k++ss+ +                                                         +vl +++vsi+ +G ++G 
  EEA20524.1  18 AISEVTSTTTNLDVEKHDSSTVDdsgngglqgdedprqwperkkmgilvmvavmtfitpmspamlssaipeiltefpttNTVLASMSVSIYALGLAVGP 116
                 566666677777777777766667777777777777777777777777777778888888888888888888888888899****************** PP

                 HHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHH. CS
    Sugar_tr  64 lfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglgl. 161
                 l++ +l++ +GR   + ++a+lf+i ++ +a+++   ++ +li+  ++ G    +  ++    ++ +   + Rga +     ++++G l+a+++g +  
  EEA20524.1 117 LIIAPLSEAYGRLVLYHATAILFIIFSIACAVST---NLNMLIAFEFFQGCMGSAPITMGGGSVADMYSREERGARIA----FLATGPLIAQFVGPVGg 208
                 **********************************...9************8777777777889999999999999986....57888888888888874 PP

                 HTSS-TTHHHHHHHCCHHHHHHHHHHGGGS CS
    Sugar_tr 162 nktsnadgwrillglqlvpallllilllfl 191
                 +   +a gwr+ ++l  +++ ++ i+ +fl
  EEA20524.1 209 SFLAAARGWRWVFWLVTILTGVIEIGYCFL 238
                 55555889*****************99997 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 0.53
                 HHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHH CS
    Sugar_tr  85 lfvigavlqaaakgknsvevlivgRvlvGigvGlasv 121
                  ++i ++ ++++  +  +e  ivg v +Gi+ G+a +
  EEA20524.1 308 YLLITTLANIFIGTY-GLEPKIVGLVYLGIATGMALG 343
                 344444444444422.566666666666666666554 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.039
                 HHHHHHHHHHHHHH..HHHHTTSS.....CHHHHHHHHHHHHHHHTTTTHHHH CS
    Sugar_tr 322 lGaagmaicfvilgivalllvaks..kaasivaivfialfialfalgwgpvpw 372
                 +G++g  ++ ++l+i ++l+ a     a si+a++ +  fi +f +  gp ++
  EEA20524.1 404 TGFLGLGLMWLLLSIDTYLVDAYPlyAASSIGATTVFRSFISAFLPLAGPSMY 456
                 68889999999999777777776688899***************999999877 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.3   5.0   7.7e-10   4.6e-06      64     208 ..      83     230 ..      63     260 .. 0.78

  Alignments for each domain:
  == domain 1  score: 25.3 bits;  conditional E-value: 7.7e-10
       TRI12  64 asalpnilqdvgqsen..sslfstlwttgqavsilvmgrltdrfgrrpfvilthilglvgaivgctatkfntllaamtllgv.aagpagasplfvgelm 159
                 +sa+p+il +   ++    s+  +++++g av  l++  l++ +gr  +  +t il ++ +i  + +t++n l+a   + g   + p       v ++ 
  EEA20524.1  83 SSAIPEILTEFPTTNTvlASMSVSIYALGLAVGPLIIAPLSEAYGRLVLYHATAILFIIFSIACAVSTNLNMLIAFEFFQGCmGSAPITMGGGSVADMY 181
                 699******9976654225777789**************************************99*******999877776514556666677788999 PP

       TRI12 160 snktkflgllivsipvvvtsglspylgqrlaiqgswrwifyiyiitsai 208
                 s   +   +  ++   ++ + ++p  g  la    wrw+f++  i++ +
  EEA20524.1 182 SREERGARIAFLATGPLIAQFVGPVGGSFLAAARGWRWVFWLVTILTGV 230
                 998888777766665555566*******************987665543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (499 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       652  (0.0363657); expected 358.6 (0.02)
Passed bias filter:                      316  (0.0176251); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.42
# Mc/sec: 3601.51
//
Query:       EEA20525.1  [L=286]
Description: 15-hydroxyprostaglandin dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.1e-33  114.9   0.0    4.2e-33  114.5   0.0    1.1  1  adh_short     short chain dehydrogenase
      5e-19   68.8   0.0    6.4e-19   68.4   0.0    1.1  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
    6.7e-05   22.9   0.0    9.6e-05   22.4   0.0    1.3  1  KR            KR domain
     0.0011   18.5   0.0     0.0014   18.1   0.0    1.2  1  Epimerase     NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.5   0.0   9.3e-37   4.2e-33       1     189 [.      11     203 ..      11     208 .. 0.92

  Alignments for each domain:
  == domain 1  score: 114.5 bits;  conditional E-value: 9.3e-37
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHH.HHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSE.SEEEE---S..S--SSGGG CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvvvdrseekle.evakelkeegakalaiqvDvtdreevealvekavkklgkl.dvLvnNAGi..tgsgpfse 95 
                 k+v+vtG++sGIG ++++   ++G +v+++d +  +++ + +ke +e+ ++++++++Dv++++++e+lv     +++ + d+ v+ AG+  t + +f e
  EEA20525.1  11 KIVVVTGGGSGIGFNFSEIAFSKGNRVIIADLRLTPAAeKFVKE-NEATKRVIFVECDVSKWKDLENLVTVSLREFEDVpDAYVAAAGLfeTSKYSFFE 108
                 79***************************998877765055555.555799*************************9998*********8877778888 PP

                 CSHHHHHHHHHHHTHHHHHHHHHHHHHHH.HCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHH CS
   adh_short  96 lseeewervievNltgvflltravlpaml.kqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmake 189
                  +ee+   +++vN   +++ltr  ++a + ++++  I  v+S+ag++p+   ++Y AsK+av+g++++++    ++++++++v+PGlv+T++ +e
  EEA20525.1 109 DNEEDHYHLMDVNASHPIKLTRIGMKASVpRNKKMVICIVASMAGLYPLYPSPVYNASKHAVVGFIKCMKPADVEENVKIVGVCPGLVATPLWTE 203
                 89999**********************77799999999*****************************************************9876 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.4   0.0   1.4e-22   6.4e-19       4     181 ..      20     203 ..      15     235 .. 0.83

  Alignments for each domain:
  == domain 1  score: 68.4 bits;  conditional E-value: 1.4e-22
                   TSHHHHHHHHHHHTT-EEEEEESSGGH.HHHHHHHHHHTTSEE.EE--TTSHHHHHHHHHHHHHHH.SSEEEEEE-----EGCSS-GGGH-HHHHHH CS
  adh_short_C2   4 sgIGraiAkalaeeGaevvltdlneea.kkrveelaeelgaev.lecDVtdeeqvealveevvekf.gklDilvnnagiapklkgpfletsreefdr 97 
                   sgIG+   + + ++G +v+++dl+    +++  +  e++++ + +ecDV++ +++e+lv    ++f +  D  v +ag  ++ k +f e ++e+  +
    EEA20525.1  20 SGIGFNFSEIAFSKGNRVIIADLRLTPaAEKFVKENEATKRVIfVECDVSKWKDLENLVTVSLREFeDVPDAYVAAAGLFETSKYSFFEDNEEDHYH 116
                   8**********************988844444444444444436**********************7777************99************* PP

                   HHHHHTHHHHHHHHHHHH.HCTSC..CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGG CS
  adh_short_C2  98 aldvnlyslfllakaalp.lmkeg..gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasg 181
                    +dvn+   ++l++  ++  + ++    i  ++s+++   +    +y+a+K+a++++++++     ++++++  v+pg+++T+++++
    EEA20525.1 117 LMDVNASHPIKLTRIGMKaSVPRNkkMVICIVASMAGLYPLYPSPVYNASKHAVVGFIKCMKPADVEENVKIVGVCPGLVATPLWTE 203
                   *****************9744444324455558888877777777****************9999999***************9653 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.4   0.0   2.1e-08   9.6e-05       3      95 ..      13     102 ..      12     155 .. 0.85

  Alignments for each domain:
  == domain 1  score: 22.4 bits;  conditional E-value: 2.1e-08
                 EEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---.EEEE-------- CS
          KR   3 ylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppik.GvihaAgvlrdk 95 
                 +++tGG  g+G  +++   +kg+r ++   R    +++++++++e ea   +v +v++Dvs+ +++e+l++   +e++ +    + aAg+++++
  EEA20525.1  13 VVVTGGGSGIGFNFSEIAFSKGNRVIIADLRL---TPAAEKFVKENEA-TKRVIFVECDVSKWKDLENLVTVSLREFEDVPdAYVAAAGLFETS 102
                 68**********************99999998...6677778998776.67999*****************99999977751456666666554 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   3.2e-07    0.0014       1     150 [.      13     171 ..      13     206 .. 0.81

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 3.2e-07
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC......EEEE--TT-HHHHHHHHHHH..T-SEEEE--S---HHHHHHSHHHHHHHH CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl......elveldltdrsalerlfkee..qpdavihlAavggvaassedpadfiekn 91 
                 ++VtG+   iG ++ +   +kg +vi  d + +  +++  ++        +ve+d+ + ++le+l+     +++ v  +  v+  +   +++  f+e+n
  EEA20525.1  13 VVVTGGGSGIGFNFSEIAFSKGNRVIIADLRLTPAAEKFVKENeatkrvIFVECDVSKWKDLENLVTVSlrEFEDVPDA-YVAAAGLFETSKYSFFEDN 110
                 68**********************9999877655554444433579999***********9999988554344444444.34444455555569***** PP

                 THHHHHHHHHHHHHTCTEEEEEEEGGGGTSCSS..SS.BSTCSTTS----SSHHHHHHHHHH CS
   Epimerase  92 lqgtlnlleaarkagvkrllflsSsevYGkdae..qp.keettltgplkpnspYaaaKlage 150
                  +  ++l+++   + + +l  ++  +  +++++  +    +++   pl+p+  Y a+K+a+ 
  EEA20525.1 111 EEDHYHLMDVNASHPI-KLTRIGMKASVPRNKKmvICiVASMAGLYPLYPSPVYNASKHAVV 171
                 ****************.****************653258999999999***********975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (286 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       406  (0.0226449); expected 358.6 (0.02)
Passed bias filter:                      375  (0.0209158); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2031.00
//
Query:       EEA20526.1  [L=492]
Description: benzoate 4-monooxygenase cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-50  171.6   0.0    3.2e-50  171.2   0.0    1.1  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  171.2   0.0   1.8e-54   3.2e-50       6     426 ..      64     488 ..      61     491 .. 0.80

  Alignments for each domain:
  == domain 1  score: 171.2 bits;  conditional E-value: 1.8e-54
                 EHHCCHCHHHHTT...TCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGH.HHHHHHHH CS
        p450   6 plplvgnllqlgr...keelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfang.ekwkklRr 100
                 p++     l+l +    +   +v+++++kkygpi r+ +++    +  +pe v+++l ++++++ g    +++++ +  ++  +++  +   ++ +lR+
  EEA20526.1  64 PWWASYTRLWLCKtiaAGDSAQVFVNVNKKYGPIARVGPNH---LLTDDPEVVRRILATRSHYTRG----PWFDSIKIDPHIPNIVSERNtGRHNRLRH 155
                 45555555566555667888999************998765...56678***********766655....79998877777777666655577777777 PP

                 HHHHHHTSHSTTTHHHHHHHHHHHHHHHHHCCCCHCS....EEETHHHHHHHHHHHHHHHHHSSHHHTTTSSH...........HHHHHHHHHHHHHHH CS
        p450 101 fltptltsfgklsleelveeeaedlveklrkkagess....elditellskaaldvigsilFgarfdlledek...........lselvkaveelssll 184
                  + +   ++ ++ +e++++e +++ +++++++  ++s     +di++ +++ a+d+i+ ++Fga+++ +e+++           ++ +v+ +  ++++ 
  EEA20526.1 156 KMSAGYAGKDIEGIEKIIDERINNWITMIKDRWISNStntkMFDIARRIQYLAVDIITHLCFGAPLGFVETDSdvynflftiesQLPIVQHFSVIIEIN 254
                 777776666577899999999888888888887777777779*************************99988776666666655555555555554333 PP

                 HCHHHHCCCCCHHHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHH CS
        p450 185 skssvqllllfpllkylptkllrklkeavkklkdlldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstls 283
                   ++v+ ll  ++lk    +   +   +  ++ ++ +k++ er    +++ k r+d+l+ +l+          l+  e  a++   l+aG+dTt++ ++
  EEA20526.1 255 --TFVERLLRWKWLKSKVAPKATDKTGI-GMIMGISKKVVDERL---QPDAKPRKDMLASFLSH--------GLTPSEAEAEISISLVAGSDTTATSMR 339
                 ..44444444444544444444444444.445555555555544...4445679*********9........6************************** PP

                 HHHHHHHHSHHHHHHHHHHHHHHCCTTT...T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS.CEEETTEEE-TT-EEEEEHHHHHT-TTTSS CS
        p450 284 waLyeLaknPevqeklreEidevlgdkr...eptyddlqklpyldavikEtLRlhpvvplllpRevtk.dvvirgylipkGtevivnlyalhrdpevfp 378
                  +L+ ++ nP v ++l++Eid ++ d r   +++ ++   lpyl+a+i E LR  p++  l +Rev+     i g+++p Gt + +n+++l+ +p + +
  EEA20526.1 340 ATLLSIISNPRVYSRLQKEIDDAIVDGRissPIQDSEARALPYLQACIAEGLRRFPPITQLREREVPPeGDIIHGHHVPGGTFIGLNAWGLQLNPIYGD 438
                 ************************88788899999999*********************999***9874777899********************999* PP

                 STTS--GGGGB-TTS..CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHH CS
        p450 379 nPeeFdpeRFldekg..nskrksfaflPFGaGpRnCiGerlArmelklfl 426
                 + e+++peR+l +++    + ++   l FG G   C+G ++A+m+l+ ++
  EEA20526.1 439 DVEVYRPERWLIDDAdrLMEMHKTHELIFGYGNTKCLGIPIAMMNLNKLF 488
                 ***********99998855589999999*****************98776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (492 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       459  (0.025601); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 3239.99
//
Query:       EEA20527.1  [L=509]
Description: cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      6e-34  117.6   0.1    6.8e-34  117.4   0.1    1.1  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.4   0.1   3.8e-38   6.8e-34     188     446 ..     217     487 ..     144     505 .. 0.85

  Alignments for each domain:
  == domain 1  score: 117.4 bits;  conditional E-value: 3.8e-38
                 HHHCCCCCH.HHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHC.SCSSCSHHHHHHHHCTTCTCT.SSSSHHHHHHHHHHHHHHHHHHHHHHHH CS
        p450 188 svqllllfp.llkylptkllrklkeavkklkdlldklieerretldsa.kksrrdfldalllakkekkge.sklsdeelaatvlellfaGvdTtsstls 283
                   + +++fp +l++l  kl  +  +++ ++++  + +i   ++ l    ++++ d+++ +++   +k g+ ++l+++  a+  l l +++++ t  tl 
  EEA20527.1 217 AAKTIKFFPvWLRPLAAKLMAQPARMRATREEAQRLVIPVLKRRLALPeNEKPDDMMQWMMNRLGDKAGTpEELHHQ--AHLQLALAMGAIHSTNFTLL 313
                 4567788999999999999888777777776665555544444444433469*********9985555554555544..455567889*********** PP

                 HHHHHHHHSHHHHHHHHHHHHHHC.CTTTT-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEETT.EEE-TT-EEEEEHHHHHT-TTTSSST CS
        p450 284 waLyeLaknPevqeklreEidevl.gdkreptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirg.ylipkGtevivnlyalhrdpevfpnP 380
                   ++ La ++e+ e lr+E +e+l +   ++t + l +l  ld + kE++R+ p+  ++  R+++kd+ +++   ip+++++ + + a++rdp++ ++P
  EEA20527.1 314 HQFFDLAAYQEYHEPLRQEYREALeKTGGKLTKATLGMLNKLDSFMKESQRYNPPGLTNGRRKTLKDIRLNDgTIIPQNSNIEIAANAVNRDPAIHEDP 412
                 ************************76667*******************************************9************************** PP

                 TS--GGGGB-TTS.........CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGEE CS
        p450 381 eeFdpeRFldekg.........nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdpppi 446
                 ++Fd  RF + ++         ++ ++s  +l  G G+++C+G+ +A  e+k++l+++Lq+++++l + ++ + +
  EEA20527.1 413 DVFDGFRFYKMRQrseedtnrhQFVSSSPNSLNWGYGRHACPGRFFAVDEIKVILSKVLQKYDISLVNPGEGRYK 487
                 ******************9999888999***********************************998765554444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (509 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       603  (0.0336327); expected 358.6 (0.02)
Passed bias filter:                      533  (0.0297284); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.34s 00:00:01.02 Elapsed: 00:00:00.54
# Mc/sec: 2818.79
//
Query:       EEA20528.1  [L=264]
Description: short chain dehydrogenase/oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      8e-48  162.5   0.2    9.7e-48  162.2   0.2    1.1  1  adh_short        short chain dehydrogenase
    1.1e-41  142.9   0.2    1.9e-40  138.9   0.2    1.9  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    1.3e-06   28.5   1.3    1.8e-05   24.7   1.3    2.1  1  KR               KR domain
    0.00016   21.3   0.0    0.00031   20.3   0.0    1.6  2  Epimerase        NAD dependent epimerase/dehydratase family
     0.0097   15.6   0.7      0.035   13.9   0.7    1.9  1  Eno-Rase_NADH_b  NAD(P)H binding domain of trans-2-enoyl-CoA 


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  162.2   0.2   2.7e-51   9.7e-48       1     191 [.       9     197 ..       9     200 .. 0.95

  Alignments for each domain:
  == domain 1  score: 162.2 bits;  conditional E-value: 2.7e-51
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHH.SSESEEEE---S.S--SSGGGCS CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkkl.gkldvLvnNAGi.tgsgpfsels 97 
                 kv++vtG+ssGIG+ +   l++ Ga+v+ +d  + +   + +e k     +++ q+D+t+++++ ++v ++++k+  ++d+Lvn AG+  g++++  ++
  EEA20528.1   9 KVAIVTGCSSGIGLSTTLSLLSHGARVLGIDVAPFDY-SLPEEQKP---LLVFHQADLTNSSAITEAVTTCKAKFgPRIDILVNAAGVgDGFSSADTVT 103
                 89*******************************9999.55555554...59************************779**********87888888999 PP

                 HHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHHC CS
   adh_short  98 eeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakelr 191
                 + ew+r+i++Nlt+++ l+ravlp m+++++G+Ivn++S a+  +   ++aY+AsK+++ag t+++a  ++++gir+nav+PG+v T++ak+++
  EEA20528.1 104 DGEWDRIISINLTAPVRLMRAVLPSMIEHQQGAIVNICSRASTSGATAGIAYTASKHGLAGATKNVAWRFRNQGIRCNAVCPGGVVTNIAKSVN 197
                 999**************************************************************************************99886 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.9   0.2   5.2e-44   1.9e-40       1     230 [.      15     258 ..      15     261 .. 0.85

  Alignments for each domain:
  == domain 1  score: 138.9 bits;  conditional E-value: 5.2e-44
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSE.E.EE--TTSHHHHHHHHHHHHHHH.SSEEEEEE-----EGCSS-GGGH-HHH CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneeakkrveelaeelgae.v.lecDVtdeeqvealveevvekf.gklDilvnnagiapklkgpfletsree 94 
                   G  sgIG  +  +l ++Ga+v+  d+   +     +l ee +   v  ++D t+ ++++++v ++++kf  ++Dilvn+ag+ +   +++ ++++ e
    EEA20528.1  15 GCSSGIGLSTTLSLLSHGARVLGIDVAPFD----YSLPEEQKPLlVfHQADLTNSSAITEAVTTCKAKFgPRIDILVNAAGVGDG-FSSADTVTDGE 106
                   6789***********************999....4555555544446**********************77*************9.7888888**** PP

                   HHHHHHHHTHHHHHHHHHHHH.HCTSC.CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTT..... CS
  adh_short_C2  95 fdraldvnlyslfllakaalp.lmkeg.gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikg..... 184
                   +dr++++nl++ ++l++a+lp +++++ g+ivn+ s +++ + +   ay+a+K++l + t+++A  + ++giR+Nav+pg + T++a++++      
    EEA20528.1 107 WDRIISINLTAPVRLMRAVLPsMIEHQqGAIVNICSRASTSGATAGIAYTASKHGLAGATKNVAWRFRNQGIRCNAVCPGGVVTNIAKSVNMecfdp 203
                   *********************7666557*****************99****************************************9998666544 PP

                   ..HHH........HHHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEES CS
  adh_short_C2 185 ..fde........lleelearaplgrlgtpeevaeaalfLasdeasyitGqtlvvD 230
                     f e        +    +   p    + pe+va+ +lfL+s++as i+G  l vD
    EEA20528.1 204 agFAEfqpifglhVGTDQATGLPAP-HIAPEDVAQGILFLVSEQASKINGVLLPVD 258
                   4433422232211122222333333.479*************************99 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   1.3     5e-09   1.8e-05       4     153 ..      12     159 ..      10     183 .. 0.86

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 5e-09
                 EEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHS.S---EEEE------.---TTT- CS
          KR   4 litGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaee.ppikGvihaAgvlr.dklleem 100
                 ++tG+  g+Gl+++  l+++gar l +               +  e++     + +aD+++++a++++++++ka++ p+i   ++aAgv +  +  +++
  EEA20528.1  12 IVTGCSSGIGLSTTLSLLSHGARVLGIDVAP-----F---DYSLPEEQKPLLVFHQADLTNSSAITEAVTTCKAKFgPRIDILVNAAGVGDgFSSADTV 102
                 89*********************88653332.....2...223345666778999*********************9************98789999** PP

                 -HHHHHHHHTTTTHHHHHHHHHTTT....S--SEEEEEEEHHHHH--TT-HHHHHHH CS
          KR 101 taedleqvlapKvkGawnLhelled....esldffvlfSSiagllgsagqanYaaaN 153
                 t+ +++++++  +++   L +++ +    ++   +v + S a++ g++   +Y+a  
  EEA20528.1 103 TDGEWDRIISINLTAPVRLMRAVLPsmieHQQGAIVNICSRASTSGATAGIAYTASK 159
                 *******************9999885666677789******************9975 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0   8.6e-08   0.00031       2      83 ..      12     101 ..      11     150 .. 0.78
   2 ?   -3.3   0.0       1.4     5e+03     216     229 ..     233     246 ..     229     251 .. 0.78

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 8.6e-08
                 EEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC..EEEE--TT-HHHHHHHHHH....H..T-SEEEE--S---HHHHHHS CS
   Epimerase   2 lVtGatGfiGsalvkallekgyevigldrlssasntarledl..elveldltdrsalerlfke....e..qpdavihlAavggvaassed 83 
                 +VtG +  iG  ++  ll++g +v+g+d  + +    ++++    ++++dlt++sa+++++ +    +  ++d+ +++A+vg+   s+++
  EEA20528.1  12 IVTGCSSGIGLSTTLSLLSHGARVLGIDVAPFDYSLPEEQKPllVFHQADLTNSSAITEAVTTckakFgpRIDILVNAAGVGDGFSSADT 101
                 8*****************************88888777666689***********98888764222233467889999888877666654 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 1.4
                 HHHHHHHHHHHHHH CS
   Epimerase 216 eDvaeaillvlehv 229
                 eDva++il+++ + 
  EEA20528.1 233 EDVAQGILFLVSEQ 246
                 8*******999874 PP

>> Eno-Rase_NADH_b  NAD(P)H binding domain of trans-2-enoyl-CoA reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   0.7   9.7e-06     0.035      40      71 ..       8      38 ..       2      42 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 9.7e-06
                     -SEEEEESTSSHHHHHHHHHHHHSS--EEEEE CS
  Eno-Rase_NADH_b 40 pkkvLviGaStGYGLAsriaaafgagadtigV 71
                      k ++v G+S+G GL++++++    ga+ +g+
       EEA20528.1  8 SKVAIVTGCSSGIGLSTTLSLLSH-GARVLGI 38
                     68999**************96544.5555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (264 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       442  (0.0246528); expected 358.6 (0.02)
Passed bias filter:                      383  (0.021362); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 1792.86
//
Query:       EEA20529.1  [L=513]
Description: cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.2e-26   91.7   0.0    1.6e-21   76.7   0.0    2.1  2  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.1   0.0   1.6e-06     0.029       1     180 [.      32     208 ..      31     261 .. 0.69
   2 !   76.7   0.0   8.7e-26   1.6e-21     277     441 ..     286     457 ..     282     481 .. 0.91

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.6e-06
                 --SESEHHCCHCHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHH...H CS
        p450   1 Ppgptplplvgnllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekw...k 96 
                 P  p+ +pl+g+l+ + r+++ +  l+   k  ++i++l + + ++ v++++++v +v  +  + +s++p   ++a +     g  +   + e++    
  EEA20529.1  32 PLLPQKIPLIGHLIGFLRNGNSYY-LDMSMKHGQQICTLGMPNGRTYVVNSTKLVSAVQRNA-KTISFDPILTTVAERLAGITGPELEALKEEETgggG 128
                 55678***********96444443.5555555579***********************9999.599999999999998877777777666655442224 PP

                 HHHHHHHHHHTSHSTT.THHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHH CS
        p450  97 klRrfltptltsfgkl.sleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveel 180
                  +R++++    s  +   l ++ + + ++l + ++k  ++s+e+d+  +  ++   ++++ +Fg +   + ++   ++++ ++e+
  EEA20529.1 129 AHRKVVHSMAPSL-IGvGLDAMNKAMLRNLENFINKLESQSQEFDLWAWTRHVISIASTDAVFGPENP-YAKN---NYEQTFWEY 208
                 6777766666655.333455555555555555555555666668999999999999999999998744.3333...345555555 PP

  == domain 2  score: 76.7 bits;  conditional E-value: 8.7e-26
                 HHHHHHHHHHHHHHHSHHHHHHHHHHHHHHCCTTT........T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEETT.EEE-TT-EEEEE CS
        p450 277 TtsstlswaLyeLaknPevqeklreEidevlgdkr........eptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirg.ylipkGtevivn 366
                 +t  t +w+L +    P++ + +r E ++ +  +r          t d ++    l  + +Et+R +       pR+v++d+ ++g yl++kG   +++
  EEA20529.1 286 NTVPTAFWTLCNVFSSPKLLADVRSEAEKLFSVDRtgpkpvytLDTSDLRTGCSILFSAYQETMRTRACFA--SPRYVLEDTLLNGeYLLKKGALLQIP 382
                 688999*************************555669*999988888999999**************9999..99************************ PP

                 HHHHHT-TTTS.SSTTS--GGGGB-TTSCTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTST CS
        p450 367 lyalhrdpevf.pnPeeFdpeRFldekgnskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpet 441
                 +  lh+++ ++ p++ ++dp RF +++   kr+++a+ +FG  p  C+G+++A++e+  f++ +  ++++++ ++t
  EEA20529.1 383 AAVLHHEQLQWgPDAATYDPYRFTKKSS-IKRSPVAYRAFGGAPALCPGRHFATVEVLCFVIMITMRYDITPADGT 457
                 ***************************9.56*********************************999999976655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (513 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       481  (0.026828); expected 358.6 (0.02)
Passed bias filter:                      465  (0.0259356); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 3518.66
//
Query:       EEA20530.1  [L=635]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    0.00014   21.0   0.0     0.0046   15.9   0.0    2.2  2  Tri3          15-O-acetyltransferase Tri3
  ------ inclusion threshold ------
      0.024   13.3   0.0      0.044   12.5   0.0    1.4  1  Condensation  Condensation domain


Domain annotation for each model (and alignments):
>> Tri3  15-O-acetyltransferase Tri3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    2.4   0.1    0.0065        58      70     117 ..     244     286 ..     237     300 .. 0.75
   2 !   15.9   0.0   5.2e-07    0.0046     170     335 ..     309     474 ..     290     483 .. 0.80

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.0065
        Tri3  70 klerallearfkhPeiaatvlWdeqvapviqyePpesdkealaWaknt 117
                  l++a  ++rf+ Peiaa  + d+ v     ye p++++e   W  +t
  EEA20530.1 244 ALRQAWKQVRFQFPEIAAYPSGDKYV-----YEVPQTEEEVTKWLSST 286
                 567888999**********9999987.....66677777777776544 PP

  == domain 2  score: 15.9 bits;  conditional E-value: 5.2e-07
        Tri3 170 vdvllhsnhlyfdGiskrlfvGdllrslaellg.teqkppelkWGeevknlgapvldllkldvealGdefddkldeyvaalvrntq....syGlrfkpd 263
                 v  + h+n +       rl  G  + +l++ +  +  +p ++++G+ev nl+++   l k+      +e +++  +   a   +      +  + +  +
  EEA20530.1 309 VHWIPHTNEVVLTSSHFRL-DGRAFMTLSNFIChALAQPKQIDFGNEVSNLSPSFEVLAKIPQAPYSPEIETAATQRLMAWGSSLPpvkiATSFSAGEK 406
                 5666777777776655554.6889999*9999878899**************99888888999999********9998875554431111444555567 PP

        Tri3 264 lGlPrvilhtltaeeseaiikavksrlgPkytiahlghaavvlallkakkPsddlpdsqilvapspvnGrrf 335
                   + r     +++ee+ +++ka ks    + ++a    a +v a  +  +P + + +s++++a  + + r++
  EEA20530.1 407 AAVSRRLTSVYSIEETSSMVKACKSN---NLSVAVALTAGLVSACCELAEP-APVDESRYFMAICAFDLRKY 474
                 788999999***************96...6778888889999999999999.89999999999999999887 PP

>> Condensation  Condensation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   4.9e-06     0.044     397     433 ..     593     629 ..     576     633 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 4.9e-06
                   EEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHH CS
  Condensation 397 asetngkltikieYntslFdeetierflerlkelleq 433
                   +++ +g+lt++ +Yn++ ++ e i+++l+++k++++q
    EEA20530.1 593 VWTLHGQLTMTACYNEAYWSPEGIQQLLDKIKQHVQQ 629
                   67789*****************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (635 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       522  (0.0291148); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.44
# Mc/sec: 4379.77
//
Query:       EEA20531.1  [L=305]
Description: 3-oxoacyl-[acyl-carrier-protein] reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.7e-37  127.1   0.1    7.6e-37  126.7   0.1    1.1  1  adh_short        short chain dehydrogenase
    5.3e-29  101.4   0.1    2.4e-28   99.3   0.1    1.8  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    1.2e-09   38.3   0.1    1.6e-09   37.9   0.1    1.2  1  KR               KR domain
     0.0016   17.6   0.1      0.002   17.3   0.1    1.2  1  Polysacc_synt_2  Polysaccharide biosynthesis protein


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  126.7   0.1   1.7e-40   7.6e-37       1     187 [.      47     234 ..      47     239 .. 0.90

  Alignments for each domain:
  == domain 1  score: 126.7 bits;  conditional E-value: 1.7e-40
                 SEEEEESTTSHHHHH.HHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHT..TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SS.GG CS
   adh_short   1 kvvlvtGassGIGra.iakelakeGakvvv.vdrseekleevakelkee..gakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgp.fs 94 
                 kv++vtGas+GIG++ i++++a++  k +v ++r+++klee+ +         +++ +++Dvt++++v++l++ +++k+gk dvLvnNAG++  ++ + 
  EEA20531.1  47 KVIVVTGASQGIGKEgIVRQFARAKPKAIViAARNADKLEETEALALGIepTVEIVRVPTDVTSEDSVKNLFDIIQQKFGKADVLVNNAGVSVGHTtVD 145
                 89***********9879******999999889********99887666658899*************************************55555055 PP

                 GCSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHH CS
   adh_short  95 elseeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdma 187
                  ++ +++ + +evN++gv+l+t+ +l+  l   +G+Ivn+sS+a+ ++ ++ a Y+ sK a+++l r+++    + + +v+a++PG +++d++
  EEA20531.1 146 MMELDDYWQNFEVNVKGVLLMTKYFLRL-LGDARGSIVNISSQAAWNEPEVSAGYCLSKLAIVKLCRQMS---GRPNLTVVALHPGTIKSDIV 234
                 5666669999*****************9.779**********************************9997...566789**********9987 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.3   0.1   5.5e-32   2.4e-28       1     179 [.      53     234 ..      53     272 .. 0.86

  Alignments for each domain:
  == domain 1  score: 99.3 bits;  conditional E-value: 5.5e-32
                   TTTTSHHH.HHHHHHHHTT-E.EEEEESSGGHHHHHHHHHHHTTSEE....EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH- CS
  adh_short_C2   1 GaasgIGr.aiAkalaeeGae.vvltdlneeakkrveelaeelgaev....lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpflets 91 
                   Ga +gIG+ +i++++a++  + +v++ +n ++ +++e+la  ++ +v    +++DVt+e++v++l++ +++kfgk D+lvnnag++   ++ +  ++
    EEA20531.1  53 GASQGIGKeGIVRQFARAKPKaIVIAARNADKLEETEALALGIEPTVeivrVPTDVTSEDSVKNLFDIIQQKFGKADVLVNNAGVSVG-HTTVDMME 148
                   899****747******99876467777777778999999999985533369************************************9.7777778* PP

                   HHHHHHHHHHHTHHHHHHHHHHHHHCTSC.CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGG CS
  adh_short_C2  92 reefdraldvnlyslfllakaalplmkeg.gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaa 179
                    +++ + ++vn+++++l++k++l+l+ +  gsivn+ss +a    +  + y+ +K a+++l+r++    g+ + +v a +pg ik +++
    EEA20531.1 149 LDDYWQNFEVNVKGVLLMTKYFLRLLGDArGSIVNISSQAAWNEPEVSAGYCLSKLAIVKLCRQMS---GRPNLTVVALHPGTIKSDIV 234
                   ************************998777*********9977777777***************96...88899**********98764 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.9   0.1   3.6e-13   1.6e-09       3     143 ..      49     193 ..      47     225 .. 0.84

  Alignments for each domain:
  == domain 1  score: 37.9 bits;  conditional E-value: 3.6e-13
                 EEEETTTSHHHHH.HHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE------.---TTT CS
          KR   3 ylitGGlGgLGle.larwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlr.dkllee 99 
                  ++tG+  g+G+e ++r+ a+   + +v+ +R+a + e+ +  +a   +  +e+  v+ Dv+++d+v++l++ i++++++    ++ Agv+   ++++ 
  EEA20531.1  49 IVVTGASQGIGKEgIVRQFARAKPKAIVIAARNADKLEETE-ALALGIEPTVEIVRVPTDVTSEDSVKNLFDIIQQKFGKADVLVNNAGVSVgHTTVDM 146
                 68*********986889999999**********76666666.4444445599************************************99653999*** PP

                 --HHHHHHHHTTTTHHHHHHHHHTTT...S--SEEEEEEEHHHHH-- CS
          KR 100 mtaedleqvlapKvkGawnLhelled...esldffvlfSSiagllgs 143
                 m+ +d+ q ++  vkG+  + +++ +   +    +v +SS a+    
  EEA20531.1 147 MELDDYWQNFEVNVKGVLLMTKYFLRllgDARGSIVNISSQAAWNEP 193
                 **********************9998555555567888888776555 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.1   4.4e-07     0.002       1      76 [.      49     121 ..      49     215 .. 0.75

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 4.4e-07
                      EEEETTTSHHHHH.HHHHHHHHB-SEEEEEES-HHHHHHHHHH......-TTEEEE....E--TT-HHHHHHHTT.. CS
  Polysacc_synt_2   1 vlvtGagGsiGse.lvrqilkkkpkkiillerdElklyeiekeleeelkkkklkveivpvigdvrdkerlekaleel 76 
                      ++vtGa+  iG+e +vrq+++ kpk i++  r+  kl e e        +   +veiv v +dv+ +++++++++ +
       EEA20531.1  49 IVVTGASQGIGKEgIVRQFARAKPKAIVIAARNADKLEETEALALG--IEP--TVEIVRVPTDVTSEDSVKNLFDII 121
                      79*********98799*********************999886532..233..357889999**9999999988643 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (305 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2101.96
//
Query:       EEA20532.1  [L=139]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-22   79.4   0.1    4.1e-22   79.1   0.1    1.1  1  EthD      EthD domain
      4e-07   30.5   0.0    5.1e-07   30.1   0.0    1.2  1  MmlI      Methylmuconolactone methyl-isomerase


Domain annotation for each model (and alignments):
>> EthD  EthD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.1   0.1   4.5e-26   4.1e-22       1      94 []      18     114 ..      18     114 .. 0.97

  Alignments for each domain:
  == domain 1  score: 79.1 bits;  conditional E-value: 4.5e-26
                 --S-HHHHHHHHHHTHHHHHCTSTT...............--EEEEEEEEEBTTC--SEEEEEEEEESSHHHHHHHHCSHHHHH.HHHHHHHHCGGX CS
        EthD   1 pglspeeFrdyweevHaplvkdllg..girryvlr.atktrpateagvalagpgsdadyDgiaelwfdsleaflaafadpeyaavlaaDeenFaDks 94 
                 +g++peeF+++w evH+p+++dl    g+++y +  +t++ +at ++va a + +  ++Dg+ae ++++l ++l+++adpey +++++De+ F+Dks
  EEA20532.1  18 EGTTPEEFYHHWYEVHGPKMLDLSLryGVVEYRQYhTTPEAKATLDVVAKAFGKDCLPCDGMAETLVRDLGTYLRMQADPEYLEKIVPDEAAFMDKS 114
                 699***********************88999999999999*******************************************************86 PP

>> MmlI  Methylmuconolactone methyl-isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.1   0.0   5.7e-11   5.1e-07       2      98 ..       8     111 ..       7     127 .. 0.75

  Alignments for each domain:
  == domain 1  score: 30.1 bits;  conditional E-value: 5.7e-11
        MmlI   2 ikrlgllsrredlsheqflahwrevhaplvhavt...Glrryqqnrvvder.ftqfvPv..veydgypvdgivelWfedlasleksfaspaak.llaah 93 
                 i+  +ll r+e+ + e+f +hw evh p   +++   G+  y+q +   e   t +v       d  p dg++e    dl ++ ++ a p++  ++  +
  EEA20532.1   8 IRITALLFRKEGTTPEEFYHHWYEVHGPKMLDLSlryGVVEYRQYHTTPEAkATLDVVAkaFGKDCLPCDGMAETLVRDLGTYLRMQADPEYLeKIVPD 106
                 78889***********************99988644466666665554332133333222266799***********************9985134455 PP

        MmlI  94 Gktfi 98 
                  ++f+
  EEA20532.1 107 EAAFM 111
                 55555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (139 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       303  (0.0169); expected 358.6 (0.02)
Passed bias filter:                      282  (0.0157287); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.37u 0.26s 00:00:00.63 Elapsed: 00:00:00.40
# Mc/sec: 1037.37
//
Query:       EEA20533.1  [L=509]
Description: cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.8e-25   89.0   0.0    1.2e-24   86.9   0.0    2.0  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.9   0.0   6.6e-29   1.2e-24       6     440 ..      39     458 ..      33     483 .. 0.67

  Alignments for each domain:
  == domain 1  score: 86.9 bits;  conditional E-value: 6.6e-29
                 EHHCCHCHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHHHHHHH CS
        p450   6 plplvgnllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkklRrfltp 104
                  +pl+g++l l     ++ + + ++k   p+f+l + ++++ v+++++ + ++ ++  +  s+ p  + +a      k  g+ +    +w     ++t+
  EEA20533.1  39 KVPLIGHVLGLIY-YGPNYYTSVAEKDRPPMFTLGIFGTRSYVVNTSQVISSIQKNA-KTLSFAPLIPYVAE-----KIAGLRVELCRTWFVDDGTYTK 130
                 5566666666664.3333334444444456666666666666666666666666655.35566555555554.....4445544444566666666666 PP

                 HHTSH......STTTHHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSH.HHHHHHHHHHHHHHHHCHHHHCCCCCH CS
        p450 105 tltsf......gklsleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledek.lselvkaveelssllskssvqllllfp 196
                  +           l   +   ++++ ++++l++  +e  +   ++ + k ++ vi+++ Fga ++  ++++ +++ +ka++e  ++  +    l   +p
  EEA20533.1 131 GMGAEhaklihHTLYTIDGSRDVNAAVLAELKPLMDEIPSWGDKFGIYKWMVHVISQTSFGAVYG-PDHPMnDPQVEKAFWEFENNAGS---LLTSAIP 225
                 66555543331122344444555556666666666666666666677777777777777777777.55544355666666666433322...2333333 PP

                 HHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHH CS
        p450 197 llkylptkllrklkeavkklkdlldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPev 295
                 +l         +++ a++ +k+l+  ++   ++  ++a ++ +++ + l ++         ++ e++a+    + +    +t+ +l+w + e++ ++ +
  EEA20533.1 226 WL---------TARTAWNGRKKLAAGFLAYYKSGNKQA-SNFVSMRKKLFEE-------HGFKIEDIAQFEAGMSTPILSNTAPALFWLIREIYARKPL 307
                 33.........344455666666666666555555555.2333333344444.......3688888888888888888899****************** PP

                 HHHHHHHHHHHC.CTTT.......T-HH.HHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEETT.EEE-TT-EEEEEHHHHHT-TTTS.SSTTS- CS
        p450 296 qeklreEidevl.gdkr.......epty.ddlqklpyldavikEtLRlhpvvplllpRevtkdvvirg.ylipkGtevivnlyalhrdpevf.pnPeeF 383
                  e +r+Ei+ ++  ++         ++  +  ++ p+l a+ +E+LRl  +      R+v++d+v+++ yl++k+t v+++ + +h++ + +  n++eF
  EEA20533.1 308 LEDIRNEIRAIItTSVGddnkpqyILEVaKLKKECPLLIAAYHEILRLNGIGT--SARRVLQDTVLDNkYLVKKDTLVLMPFSPVHQETDAWgVNAKEF 404
                 ********999855444677555544442455789***************999..66****************************************** PP

                 -GGGGB-TTSCTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTS CS
        p450 384 dpeRFldekgnskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpe 440
                 d+ R l+++    r+ + f  FG  p+ C+G+++A++e+  + a l+ +++ve+  +
  EEA20533.1 405 DITRHLNKER---RPAVTFRSFGGAPHLCPGRQIATLEILCIAAMLIVRYDVEPTLG 458
                 ********87...9***************************************7544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (509 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       416  (0.0232026); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 3479.69
//
Query:       EEA20534.1  [L=276]
Description: hypothetical protein PMAA_043680 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        3.8    7.9  16.6        3.7    7.9   1.0    3.7  3  Granulin  Granulin


Domain annotation for each model (and alignments):
>> Granulin  Granulin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   4.4   0.00072        13      12      38 ..      52      80 ..      47      82 .. 0.82
   2 ?    7.9   1.0   0.00021       3.7      20      35 ..      79      94 ..      77      99 .. 0.81
   3 ?    0.9   0.1     0.033     6e+02      16      34 ..     158     177 ..     155     182 .. 0.73

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.00072
                EEESSSSTTSSTTT..TSSSTTSEEECTT CS
    Granulin 12 CCplpnAvcCeDgk..hCCPegykCdleg 38
                 Cp +  +c + g+   CC +g++C +++
  EEA20534.1 52 NCPANFNTCSNEGNsgICCISGTTCTVDA 80
                59999999999888557********9875 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.00021
                TSSTTTTSSSTTSEEE CS
    Granulin 20 cCeDgkhCCPegykCd 35
                + +++  CCP g  C 
  EEA20534.1 79 DAANNYACCPTGALCT 94
                6678899******996 PP

  == domain 3  score: 0.9 bits;  conditional E-value: 0.033
                 SSSTTSSTTTTSSSTTS.EE CS
    Granulin  16 pnAvcCeDgkhCCPegy.kC 34 
                  nA  C+   + C  +y +C
  EEA20534.1 158 GNAAICSSYYSFCQGEYtSC 177
                 57777888888888887666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (276 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       570  (0.0317921); expected 358.6 (0.02)
Passed bias filter:                      169  (0.00942607); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.23s 00:00:00.72 Elapsed: 00:00:00.43
# Mc/sec: 1915.01
//
Query:       EEA20535.1  [L=342]
Description: mitochondrial carrier protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.5e-53  177.9   2.4    1.3e-18   66.7   0.2    3.1  3  Mito_carr  Mitochondrial carrier protein


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.2   0.0     2e-17   3.6e-13       7      90 ..      26     105 ..      21     111 .. 0.90
   2 !   66.7   0.2   7.4e-23   1.3e-18       3      94 ..     132     218 ..     130     221 .. 0.96
   3 !   60.7   0.0   5.3e-21   9.4e-17       4      89 ..     245     325 ..     242     330 .. 0.95

  Alignments for each domain:
  == domain 1  score: 49.2 bits;  conditional E-value: 2e-17
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHH.HHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   7 kellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiyke.eGlrglyrGllpnllrvapasalkfvlyetlk 90 
                  +++aG+++g++++++ +P d++Ktr+q q+k++++     +l +++ki+ + + +r l+rG lp+ lr+   sal+f++ + l+
  EEA20535.1  26 FHFAAGLASGLTSSILLQPADLLKTRVQQQSKRTAS-----LLATIRKILSSpNPIRNLWRGTLPSALRTGFGSALYFTSLNALR 105
                 589******************************999.....9********862667**********************9887766 PP

  == domain 2  score: 66.7 bits;  conditional E-value: 7.4e-23
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
   Mito_carr   3 lsvlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlll 94 
                 ls +++ll+G++a ++a+++++P+ v+K+r  ++   +++     +  + k i+++eG+rgl+ G++++ +r ap+++l++++ye+lkr++ 
  EEA20535.1 132 LSHTANLLTGAVARTTAGFIMMPVTVLKVRYESDYYAYRS-----LTGAAKDIFRTEGVRGLFAGFGATAVRDAPYAGLYVAFYEQLKRTFG 218
                 67889********************************999.....99******************************************985 PP

  == domain 3  score: 60.7 bits;  conditional E-value: 5.3e-21
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   4 svlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetl 89 
                 s++ ++++G+la+ +at +t+P+d vKtr+q+q++++++     ++++l+ ++ke+G r+l +Gl+ ++ r a +sal +++ye l
  EEA20535.1 245 STTINFASGALAAGLATAITNPFDAVKTRIQLQPGKYRN-----MIHALRLMIKEDGGRSLMSGLGLRMGRKALSSALAWTVYEEL 325
                 67789*******************************998.....****************************************87 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       430  (0.0239835); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.24s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2470.42
//
Query:       EEA20536.1  [L=534]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (534 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3647  (0.203413); expected 358.6 (0.02)
Passed bias filter:                      660  (0.0368119); expected 358.6 (0.02)
Passed Vit filter:                       186  (0.0103743); expected 17.9 (0.001)
Passed Fwd filter:                        45  (0.0025099); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 1.34u 0.38s 00:00:01.72 Elapsed: 00:00:00.59
# Mc/sec: 2717.93
//
Query:       EEA20537.1  [L=297]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.9e-30  104.0   0.3    1.3e-29  103.4   0.3    1.3  1  NmrA             NmrA-like family
    2.6e-12   47.0   0.0    5.8e-12   45.9   0.0    1.7  2  NAD_binding_10   NAD(P)H-binding
    2.7e-05   24.4   0.5      0.012   15.9   0.0    2.4  2  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma
  ------ inclusion threshold ------
      0.076   12.5   0.0       0.13   11.7   0.0    1.3  1  CbiJ             Precorrin-6x reductase CbiJ/CobK
      0.092   12.7   0.2       0.28   11.1   0.0    1.7  2  KR               KR domain


Domain annotation for each model (and alignments):
>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.4   0.3   3.7e-33   1.3e-29       1     228 [.       6     227 ..       6     260 .. 0.87

  Alignments for each domain:
  == domain 1  score: 103.4 bits;  conditional E-value: 3.7e-33
                 EEESSTTSHHHHHHHHHHHH..HT-EEEEEES-S-SHHHHHHHHSTTEEEES-TT-HHHHHHHHTT-SEEEE---GGS-HHHHHHHHHHHHHHHS-SEE CS
        NmrA   1 IlviGaTGrqGksvvrallk..aghkvralvRdtkselakslkeaGvelvkgdlddkeslvealkgvdvvfsvtgfyskeiedgkklvdAakeaGvkhf 97 
                 ++v+G+ G++  ++++al+k  ++++v +l R++++ +a     +Gv+ +k d + ++slv+alkg d+v+s+++  +  i+d+kk++dAa e Gvk+f
  EEA20537.1   6 VIVVGGGGNLSPAIIDALVKspHNYTVSVLSREQSTYQA----PSGVKHLKTD-YTHDSLVSALKGQDAVISAIA--GFAIADQKKIIDAAIEVGVKRF 97 
                 68******************99999*******9988877....57******99.679******************..********************** PP

                 EEEE---GG.GT.SSS---TTTHHHHHHHHHHHHC..TS-EEEEEE-EEGGG-BSSS-SS-BEEE-TTS.-EEEEESS-TTS-EE.-HHHHHHHHHHHH CS
        NmrA  98 iySslgddndrsnaeepavphfdsKaeieeyvral..gipytfvyagffmenflsllaqlkvgdtappedkvtllgpgnpkavll.daeeDiGafviki 193
                 ++S++g+d   ++ +    p ++ K+ei++y+++    i  t v  +ff    l++         a+++ ++t+    + +  +  ++  D+G++v+++
  EEA20537.1  98 FPSEFGSDT-TTSLALDYFPGWAPKVEIRDYLKSKedKIEWTVVFNNFFFDWGLKVGFI---AFNAKDK-TATIFPKYK-DVTFSaTNLGDVGNAVAQA 190
                 *********.55577779***************99889**************9994443...4444444.455544444.344445799********** PP

                 HHH..HHHHTTEEEEE-SEEE-HHHHHHHHHHHHTS- CS
        NmrA 194 lkd..prklkgkriklagntlsgneivelfekkigkt 228
                 l+     k+ ++++++ + t s  e++++fek++g++
  EEA20537.1 191 LSPeiAPKTANQILRIRTLTTSQSELLAAFEKATGEK 227
                 *98544556888899999999**************97 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.9   0.0   1.6e-15   5.8e-12       1     149 [.      10     148 ..      10     194 .. 0.74
   2 ?   -2.2   0.0       0.9   3.2e+03      53      53 ..     241     241 ..     195     270 .. 0.57

  Alignments for each domain:
  == domain 1  score: 45.9 bits;  conditional E-value: 1.6e-15
                     TTTSHHHHHHHHHHHHC-.T-EEEEEETTHHHCHHHHCTTTCEEEE--TT-CCHHHHHHTT-SEEEES---TCCHHHHHHHHHHHHHHCT--EEE CS
  NAD_binding_10   1 GAtGkvGrllvkellarg.ghevtalvRnpeklaeleaeeglevvegdvtdvedlaealkgadaVvsalggggkdeegaknivdaakeagvkRfv 94 
                     G+ G+   ++++ l+++  +++v +l R+++  +   a +g++ ++ d t +++l +alkg+daV+sa++g +      k+i+daa e gvkRf 
      EEA20537.1  10 GGGGNLSPAIIDALVKSPhNYTVSVLSREQSTYQ---APSGVKHLKTDYT-HDSLVSALKGQDAVISAIAGFAI--ADQKKIIDAAIEVGVKRFF 98 
                     788999999********75555555555555555...689*********9.9*****************99987..348***************8 PP

                     EEEETTTTSGCGCHHHHHHHHCCHHHHHHHHHHHHHHHH..SSSEEEEEEE-CEE-S CS
  NAD_binding_10  95 lvsaigvgdevpgefgewnkellkaylaakraaeellra..sgldwTivrpggLtde 149
                       s +g++  +  ++       + + +a k +  ++l++   +++wT+v   ++ d 
      EEA20537.1  99 P-SEFGSDTTTSLAL------DYFPGWAPKVEIRDYLKSkeDKIEWTVVFNNFFFDW 148
                     8.7788884322222......234666777777777766435777777766666665 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.9
                     H CS
  NAD_binding_10  53 d 53 
                     +
      EEA20537.1 241 E 241
                     1 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   3.2e-06     0.012       1      94 [.       6      94 ..       6     100 .. 0.81
   2 !    6.3   0.1    0.0031        11       9      72 ..     187     251 ..     180     253 .. 0.77

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 3.2e-06
                     EEEE--.SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHHHTTSSEEEE-SSGG...GHHHHHHHHHHH CS
  Sacchrp_dh_NADP  1 vliiGa.GsvGqavaellarhfdvdaeitvadrskeklealaakalgvrfeaialdaenyeavLaallkegdlvvnlsppi...ssldvlkaCiet 92
                     v+++G+ G+ + a+++ l+++ +   ++ v +r+++  +a       + ++  + d   +++ L+++lk++d+v++++  +      ++++a+ie 
       EEA20537.1  6 VIVVGGgGNLSPAIIDALVKSPHN-YTVSVLSREQSTYQAP------SGVKHLKTDY-THDS-LVSALKGQDAVISAIAGFaiaDQKKIIDAAIEV 92
                     6788888*************9876.5999999999995555......3344444443.3445.999**************9999999********* PP

                     T- CS
  Sacchrp_dh_NADP 93 gv 94
                     gv
       EEA20537.1 93 GV 94
                     98 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0031
                      HHHHHHHHHHCTCCT-G.EEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHHHTTSSE CS
  Sacchrp_dh_NADP   9 vGqavaellarhfdvda.eitvadrskeklealaakalgvrfeaialdaenyeavLaallkegdl 72 
                      v+qa+ +++a +   +  +i   + s+++l a+++ka+g++f+ ++ d + + +  ++ l++gd+
       EEA20537.1 187 VAQALSPEIAPKTANQIlRIRTLTTSQSELLAAFEKATGEKFTVTEADLDAEVSEAKEKLSKGDF 251
                      44445555555555444899999************************999999989999999987 PP

>> CbiJ  Precorrin-6x reductase CbiJ/CobK
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   3.6e-05      0.13       2      92 ..       7      95 ..       5      99 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 3.6e-05
                EEEE-SSHHHHHHHHHHHHTT--EEEEE---SSS----S..S-EEES--SHHHHHHHHHHHT--EEEE-S-TT-HHHHHHHHHHHHHHT-E CS
        CbiJ  2 ililgGTsearelaeaLaeagievvvsvateygaellpekklevrvgrlgeeglaellreekidlvvDATHPfAaeisanaaeackelgip 92
                i++ gG + + ++++aL +  ++++vsv ++ ++    +++++      + + l + l+ +  d+v+ A   fA   ++++++a+ e+g++
  EEA20537.1  7 IVVGGGGNLSPAIIDALVKSPHNYTVSVLSREQSTYQAPSGVKHLKTDYTHDSLVSALKGQ--DAVISAIAGFAIADQKKIIDAAIEVGVK 95
                445556666***********************99999999******************887..8*********************999987 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   7.7e-05      0.28       3      59 ..       6      75 ..       5      95 .. 0.76
   2 ?   -1.3   0.0       0.5   1.8e+03      23      63 ..     198     236 ..     180     266 .. 0.51

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 7.7e-05
                EEEETTTSHHHHHHHHHHHHHH.S-EEEEE-SS..............--HHHHHHHHHHHHTT-EEEE-- CS
          KR  3 ylitGGlGgLGlelarwlaekg.arhlvllsRsa............aadedskaliaelealgaevevva 59
                ++++GG G+L  ++++ l+++  + ++ +lsR++            ++d ++++l+++l+ ++a ++++a
  EEA20537.1  6 VIVVGGGGNLSPAIIDALVKSPhNYTVSVLSREQstyqapsgvkhlKTDYTHDSLVSALKGQDAVISAIA 75
                589****************987588999*****8777777777766666666678888888888777766 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.5
                 HHS-EEEEE-SS..--HHHHHHHHHHHHT.T-EEEE----TT CS
          KR  23 kgarhlvllsRsaaadedskaliaeleal.gaevevvaaDvs 63 
                 k a++++   R+   + ++++l+a++e+  g + +v +aD+ 
  EEA20537.1 198 KTANQILR-IRT--LTTSQSELLAAFEKAtGEKFTVTEADLD 236
                 34444333.233..3444455666666654666666666642 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (297 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       616  (0.0343577); expected 358.6 (0.02)
Passed bias filter:                      519  (0.0289475); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2069.32
//
Query:       EEA20538.1  [L=297]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.9e-30  104.0   0.3    1.3e-29  103.4   0.3    1.3  1  NmrA             NmrA-like family
    2.6e-12   47.0   0.0    5.8e-12   45.9   0.0    1.7  2  NAD_binding_10   NAD(P)H-binding
    2.7e-05   24.4   0.5      0.012   15.9   0.0    2.4  2  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma
  ------ inclusion threshold ------
      0.076   12.5   0.0       0.13   11.7   0.0    1.3  1  CbiJ             Precorrin-6x reductase CbiJ/CobK
      0.092   12.7   0.2       0.28   11.1   0.0    1.7  2  KR               KR domain


Domain annotation for each model (and alignments):
>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.4   0.3   3.7e-33   1.3e-29       1     228 [.       6     227 ..       6     260 .. 0.87

  Alignments for each domain:
  == domain 1  score: 103.4 bits;  conditional E-value: 3.7e-33
                 EEESSTTSHHHHHHHHHHHH..HT-EEEEEES-S-SHHHHHHHHSTTEEEES-TT-HHHHHHHHTT-SEEEE---GGS-HHHHHHHHHHHHHHHS-SEE CS
        NmrA   1 IlviGaTGrqGksvvrallk..aghkvralvRdtkselakslkeaGvelvkgdlddkeslvealkgvdvvfsvtgfyskeiedgkklvdAakeaGvkhf 97 
                 ++v+G+ G++  ++++al+k  ++++v +l R++++ +a     +Gv+ +k d + ++slv+alkg d+v+s+++  +  i+d+kk++dAa e Gvk+f
  EEA20538.1   6 VIVVGGGGNLSPAIIDALVKspHNYTVSVLSREQSTYQA----PSGVKHLKTD-YTHDSLVSALKGQDAVISAIA--GFAIADQKKIIDAAIEVGVKRF 97 
                 68******************99999*******9988877....57******99.679******************..********************** PP

                 EEEE---GG.GT.SSS---TTTHHHHHHHHHHHHC..TS-EEEEEE-EEGGG-BSSS-SS-BEEE-TTS.-EEEEESS-TTS-EE.-HHHHHHHHHHHH CS
        NmrA  98 iySslgddndrsnaeepavphfdsKaeieeyvral..gipytfvyagffmenflsllaqlkvgdtappedkvtllgpgnpkavll.daeeDiGafviki 193
                 ++S++g+d   ++ +    p ++ K+ei++y+++    i  t v  +ff    l++         a+++ ++t+    + +  +  ++  D+G++v+++
  EEA20538.1  98 FPSEFGSDT-TTSLALDYFPGWAPKVEIRDYLKSKedKIEWTVVFNNFFFDWGLKVGFI---AFNAKDK-TATIFPKYK-DVTFSaTNLGDVGNAVAQA 190
                 *********.55577779***************99889**************9994443...4444444.455544444.344445799********** PP

                 HHH..HHHHTTEEEEE-SEEE-HHHHHHHHHHHHTS- CS
        NmrA 194 lkd..prklkgkriklagntlsgneivelfekkigkt 228
                 l+     k+ ++++++ + t s  e++++fek++g++
  EEA20538.1 191 LSPeiAPKTANQILRIRTLTTSQSELLAAFEKATGEK 227
                 *98544556888899999999**************97 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.9   0.0   1.6e-15   5.8e-12       1     149 [.      10     148 ..      10     194 .. 0.74
   2 ?   -2.2   0.0       0.9   3.2e+03      53      53 ..     241     241 ..     195     270 .. 0.57

  Alignments for each domain:
  == domain 1  score: 45.9 bits;  conditional E-value: 1.6e-15
                     TTTSHHHHHHHHHHHHC-.T-EEEEEETTHHHCHHHHCTTTCEEEE--TT-CCHHHHHHTT-SEEEES---TCCHHHHHHHHHHHHHHCT--EEE CS
  NAD_binding_10   1 GAtGkvGrllvkellarg.ghevtalvRnpeklaeleaeeglevvegdvtdvedlaealkgadaVvsalggggkdeegaknivdaakeagvkRfv 94 
                     G+ G+   ++++ l+++  +++v +l R+++  +   a +g++ ++ d t +++l +alkg+daV+sa++g +      k+i+daa e gvkRf 
      EEA20538.1  10 GGGGNLSPAIIDALVKSPhNYTVSVLSREQSTYQ---APSGVKHLKTDYT-HDSLVSALKGQDAVISAIAGFAI--ADQKKIIDAAIEVGVKRFF 98 
                     788999999********75555555555555555...689*********9.9*****************99987..348***************8 PP

                     EEEETTTTSGCGCHHHHHHHHCCHHHHHHHHHHHHHHHH..SSSEEEEEEE-CEE-S CS
  NAD_binding_10  95 lvsaigvgdevpgefgewnkellkaylaakraaeellra..sgldwTivrpggLtde 149
                       s +g++  +  ++       + + +a k +  ++l++   +++wT+v   ++ d 
      EEA20538.1  99 P-SEFGSDTTTSLAL------DYFPGWAPKVEIRDYLKSkeDKIEWTVVFNNFFFDW 148
                     8.7788884322222......234666777777777766435777777766666665 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.9
                     H CS
  NAD_binding_10  53 d 53 
                     +
      EEA20538.1 241 E 241
                     1 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   3.2e-06     0.012       1      94 [.       6      94 ..       6     100 .. 0.81
   2 !    6.3   0.1    0.0031        11       9      72 ..     187     251 ..     180     253 .. 0.77

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 3.2e-06
                     EEEE--.SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHHHTTSSEEEE-SSGG...GHHHHHHHHHHH CS
  Sacchrp_dh_NADP  1 vliiGa.GsvGqavaellarhfdvdaeitvadrskeklealaakalgvrfeaialdaenyeavLaallkegdlvvnlsppi...ssldvlkaCiet 92
                     v+++G+ G+ + a+++ l+++ +   ++ v +r+++  +a       + ++  + d   +++ L+++lk++d+v++++  +      ++++a+ie 
       EEA20538.1  6 VIVVGGgGNLSPAIIDALVKSPHN-YTVSVLSREQSTYQAP------SGVKHLKTDY-THDS-LVSALKGQDAVISAIAGFaiaDQKKIIDAAIEV 92
                     6788888*************9876.5999999999995555......3344444443.3445.999**************9999999********* PP

                     T- CS
  Sacchrp_dh_NADP 93 gv 94
                     gv
       EEA20538.1 93 GV 94
                     98 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0031
                      HHHHHHHHHHCTCCT-G.EEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHHHTTSSE CS
  Sacchrp_dh_NADP   9 vGqavaellarhfdvda.eitvadrskeklealaakalgvrfeaialdaenyeavLaallkegdl 72 
                      v+qa+ +++a +   +  +i   + s+++l a+++ka+g++f+ ++ d + + +  ++ l++gd+
       EEA20538.1 187 VAQALSPEIAPKTANQIlRIRTLTTSQSELLAAFEKATGEKFTVTEADLDAEVSEAKEKLSKGDF 251
                      44445555555555444899999************************999999989999999987 PP

>> CbiJ  Precorrin-6x reductase CbiJ/CobK
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   3.6e-05      0.13       2      92 ..       7      95 ..       5      99 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 3.6e-05
                EEEE-SSHHHHHHHHHHHHTT--EEEEE---SSS----S..S-EEES--SHHHHHHHHHHHT--EEEE-S-TT-HHHHHHHHHHHHHHT-E CS
        CbiJ  2 ililgGTsearelaeaLaeagievvvsvateygaellpekklevrvgrlgeeglaellreekidlvvDATHPfAaeisanaaeackelgip 92
                i++ gG + + ++++aL +  ++++vsv ++ ++    +++++      + + l + l+ +  d+v+ A   fA   ++++++a+ e+g++
  EEA20538.1  7 IVVGGGGNLSPAIIDALVKSPHNYTVSVLSREQSTYQAPSGVKHLKTDYTHDSLVSALKGQ--DAVISAIAGFAIADQKKIIDAAIEVGVK 95
                445556666***********************99999999******************887..8*********************999987 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   7.7e-05      0.28       3      59 ..       6      75 ..       5      95 .. 0.76
   2 ?   -1.3   0.0       0.5   1.8e+03      23      63 ..     198     236 ..     180     266 .. 0.51

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 7.7e-05
                EEEETTTSHHHHHHHHHHHHHH.S-EEEEE-SS..............--HHHHHHHHHHHHTT-EEEE-- CS
          KR  3 ylitGGlGgLGlelarwlaekg.arhlvllsRsa............aadedskaliaelealgaevevva 59
                ++++GG G+L  ++++ l+++  + ++ +lsR++            ++d ++++l+++l+ ++a ++++a
  EEA20538.1  6 VIVVGGGGNLSPAIIDALVKSPhNYTVSVLSREQstyqapsgvkhlKTDYTHDSLVSALKGQDAVISAIA 75
                589****************987588999*****8777777777766666666678888888888777766 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.5
                 HHS-EEEEE-SS..--HHHHHHHHHHHHT.T-EEEE----TT CS
          KR  23 kgarhlvllsRsaaadedskaliaeleal.gaevevvaaDvs 63 
                 k a++++   R+   + ++++l+a++e+  g + +v +aD+ 
  EEA20538.1 198 KTANQILR-IRT--LTTSQSELLAAFEKAtGEKFTVTEADLD 236
                 34444333.233..3444455666666654666666666642 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (297 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       616  (0.0343577); expected 358.6 (0.02)
Passed bias filter:                      519  (0.0289475); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2087.67
//
Query:       EEA20539.1  [L=357]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
     0.0022   16.3   0.2     0.0031   15.8   0.2    1.2  1  BIV_Env     Bovine immunodeficiency virus surface protein (SU
  ------ inclusion threshold ------
       0.18   10.5   3.3        0.3    9.8   3.3    1.5  1  Presenilin  Presenilin


Domain annotation for each model (and alignments):
>> BIV_Env  Bovine immunodeficiency virus surface protein (SU)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.2   3.4e-07    0.0031      82     127 ..      20      65 ..      10     111 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 3.4e-07
     BIV_Env  82 qlciylalGetsrrldsdswkwvrkvliiailgtltmagtaladad 127
                 +  i++al  ++r l+++ w w   v++ia+ g l magt +   +
  EEA20539.1  20 LQVIFVALRMATRVLNHKAWGWDDIVILIALAGQLGMAGTMIGYIK 65 
                 45699***********************************986555 PP

>> Presenilin  Presenilin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   3.3   3.4e-05       0.3      51     125 ..      82     160 ..      17     199 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 3.4e-05
  Presenilin  51 dstgqkllnsllnalililvivvvtfllvlLykyrcykvikgwlilssll...lLflvsgllla.evlkaynipldyit 125
                 +   + +  s++ a+i ++++ v  f l+lLy   + k +++ l++  l+   +L  ++ +++   +++   + +dyi 
  EEA20539.1  82 ERLVTGFKYSFVIAVIYVVFVNVPKFALLLLYNRVFPKPLRANLFVRLLMvflILHTIGATIALvVICHPSTVDFDYIY 160
                 5556778889********************************9987655500045555544433144445577777775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (357 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       536  (0.0298957); expected 358.6 (0.02)
Passed bias filter:                      258  (0.0143901); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.22s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 2597.85
//
Query:       EEA20540.1  [L=120]
Description: prefoldin subunit 1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.6e-21   74.3   4.7      8e-21   74.0   4.7    1.2  1  Prefoldin_2  Prefoldin subunit
     0.0016   18.4   6.6       0.28   11.2   0.2    2.3  2  FlxA         FlxA-like protein
  ------ inclusion threshold ------
      0.014   15.7   1.5      0.029   14.7   1.4    1.6  1  CCDC-167     Coiled-coil domain-containing protein 167
      0.015   15.5   4.2      0.078   13.2   0.2    2.2  2  Fib_alpha    Fibrinogen alpha/beta chain family
      0.015   15.5   0.7      0.018   15.2   0.7    1.1  1  SMODS        Second Messenger Oligonucleotide or Dinucleotide
      0.051   13.9   5.6       0.95    9.8   0.2    2.3  2  DUF5082      Domain of unknown function (DUF5082)
      0.056   13.5   8.4       0.47   10.6   1.2    2.1  2  Swi5         Swi5
      0.069   13.6   4.3       0.84   10.0   0.4    2.1  2  DUF4200      Domain of unknown function (DUF4200)
      0.076   12.5   4.5       0.11   11.9   4.5    1.2  1  HMMR_N       Hyaluronan mediated motility receptor N-terminal
       0.08   12.8   3.6       0.27   11.1   3.6    1.9  1  T6PP_N       Trehalose-6-phosphate phosphatase N-terminal hel
       0.11   13.0   0.4       0.11   13.0   0.4    2.1  2  ZapB         Cell division protein ZapB
       0.63   10.7   6.9          4    8.1   2.5    2.3  2  SlyX         SlyX
          3    8.5   5.7          3    8.5   0.7    2.0  2  YabA         Initiation control protein YabA
        8.1    6.9   9.2        2.3    8.6   1.1    2.6  3  Csm1_N       Csm1 N-terminal domain


Domain annotation for each model (and alignments):
>> Prefoldin_2  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.0   4.7   6.3e-24     8e-21       4     105 ..      16     117 ..       8     118 .. 0.95

  Alignments for each domain:
  == domain 1  score: 74.0 bits;  conditional E-value: 6.3e-24
                  HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS-TT--EEEEETTEEEEE-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
  Prefoldin_2   4 inkfqqlqqqlqqlaqqikqletqlkelelvleelelldedtkvyklvGdvlvkqdkeevkeeLeerketlekeiktlekqleklekeleelkeelqk 101
                    +    qqq++ +++qi++++++++ l+l++ el +l +dt+vy+ vG+++v+++ + v+++L  +  tl+k i+ lek+l++le++ e+ ke++ +
   EEA20540.1  16 ESRAIVAQQQISIVKTQIATKQRDIRLLQLTSSELGSLSKDTNVYEGVGKMFVQTPIDAVNSRLSSEDQTLKKDISDLEKRLHYLETTHEKSKEHIEQ 113
                  5566778******************************************************************************************9 PP

                  CTS- CS
  Prefoldin_2 102 klqq 105
                   + +
   EEA20540.1 114 IFRG 117
                  9875 PP

>> FlxA  FlxA-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   2.1   0.00066      0.85      55      73 ..      23      41 ..       6      65 .. 0.79
   2 !   11.2   0.2   0.00022      0.28       5      46 ..      69     110 ..      67     115 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00066
        FlxA 55 qaQIqqlqaQIaqlqqqqa 73
                q+QI++++ QIa +q++ +
  EEA20540.1 23 QQQISIVKTQIATKQRDIR 41
                99************99865 PP

  == domain 2  score: 11.2 bits;  conditional E-value: 0.00022
        FlxA   5 sasssssssgsasqiasLqkQiknlqkqLkelsesdeltkee 46 
                 ++   + +s  +s+ ++L+k i++l+k L  l ++ e++ke 
  EEA20540.1  69 QTPIDAVNSRLSSEDQTLKKDISDLEKRLHYLETTHEKSKEH 110
                 5666677888999999*******************9999993 PP

>> CCDC-167  Coiled-coil domain-containing protein 167
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   1.4   2.3e-05     0.029      11      68 ..      24     107 ..       6     109 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 2.3e-05
    CCDC-167  11 eklascrerLeaverrlrkeelseee..........................ResleeEeaslkeqleenekeLksLrkeNrks 68 
                 ++++ ++ ++ +  r +r  +l++ e                            +l  E ++lk+++++ ek+L+ L   + ks
  EEA20540.1  24 QQISIVKTQIATKQRDIRLLQLTSSElgslskdtnvyegvgkmfvqtpidavNSRLSSEDQTLKKDISDLEKRLHYLETTHEKS 107
                 555555555555566666666666666666677788888888888888888888999*********************999997 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.5     0.045        57      87     108 ..      23      44 ..       5      57 .. 0.55
   2 ?   13.2   0.2   6.1e-05     0.078      24      61 ..      77     114 ..      74     119 .. 0.91

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.045
                 HHCCCHHHHHHHCCHHHHHHHH CS
   Fib_alpha  87 eeeilrlketidaqesnirvLq 108
                 +++i+ +k +i ++ + ir Lq
  EEA20540.1  23 QQQISIVKTQIATKQRDIRLLQ 44 
                 3344555555555555555555 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 6.1e-05
                 HCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHH CS
   Fib_alpha  24 dlllkyekdvkkdlekleneleeisnstkeaeelvkei 61 
                   l++ ++++kkd+++le++l+ ++ ++++++e++++i
  EEA20540.1  77 SRLSSEDQTLKKDISDLEKRLHYLETTHEKSKEHIEQI 114
                 5689999****************************998 PP

>> SMODS  Second Messenger Oligonucleotide or Dinucleotide Synthetase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   0.7   1.4e-05     0.018       7     110 ..       8     107 ..       1     116 [. 0.82

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1.4e-05
       SMODS   7 FkeflsnielsqttkdsissrvkaitkrLnkdfrelkskiaesllvGSyardTaikpvsdkdmlfeldvdllvvvnevegdepsdlleklkkalkktyk 105
                 +++++++ie    ++  ++++++ +++++ +++r+++     s   GS  +dT +     k m ++ ++d +    ++e+++ ++ + +l+k l+   +
  EEA20540.1   8 LQKLVQEIES---RAIVAQQQISIVKTQIATKQRDIRLLQLTSSELGSLSKDTNVYEGVGK-MFVQTPIDAVNSRLSSEDQTLKKDISDLEKRLHYLET 102
                 5566666654...77788999*****************999999************99999.********99999999999999999999999954444 PP

       SMODS 106 sseir 110
                 + e++
  EEA20540.1 103 THEKS 107
                 43333 PP

>> DUF5082  Domain of unknown function (DUF5082)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   1.4    0.0086        11       8      40 ..      22      54 ..      11      61 .. 0.85
   2 ?    9.8   0.2   0.00074      0.95      82     116 ..      68     102 ..      57     109 .. 0.92

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0086
     DUF5082  8 lqaqiaelrseiaaleekIerLkeaktklsdek 40
                +q+qi+  + +ia+ + +I+ L+ ++++l + +
  EEA20540.1 22 AQQQISIVKTQIATKQRDIRLLQLTSSELGSLS 54
                689999999999999999999999998887765 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00074
     DUF5082  82 yvdkldelidaieeEIerLenqiseaqgvldtlqs 116
                 +++ +d++ +++++E ++L+++is++++ l +l++
  EEA20540.1  68 VQTPIDAVNSRLSSEDQTLKKDISDLEKRLHYLET 102
                 67889************************999876 PP

>> Swi5  Swi5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   1.0    0.0042       5.4       7      44 ..       7      44 ..       5      45 .. 0.94
   2 ?   10.6   1.2   0.00037      0.47       5      43 ..      76     114 ..      72     115 .. 0.91

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0042
                HHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHH CS
        Swi5  7 eleeqleelekelaelkeelkekkdpeetvkrhIklLh 44
                +l++ ++e+e+    ++++    k+  +t++r I+lL+
  EEA20540.1  7 ALQKLVQEIESRAIVAQQQISIVKTQIATKQRDIRLLQ 44
                799999******************************98 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00037
                 HHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHH CS
        Swi5   5 ikeleeqleelekelaelkeelkekkdpeetvkrhIklL 43 
                 +++l ++ ++l+k++++l+++l+  ++ +e  k+hI+++
  EEA20540.1  76 NSRLSSEDQTLKKDISDLEKRLHYLETTHEKSKEHIEQI 114
                 68899*******************************975 PP

>> DUF4200  Domain of unknown function (DUF4200)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.4   0.00066      0.84      50      92 ..       8      50 ..       6      59 .. 0.89
   2 ?    5.3   0.3      0.02        26      87     106 ..      81     100 ..      68     114 .. 0.51

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00066
     DUF4200 50 fdkflkendakraralkkaeeerklkkekeaeikklkaeietl 92
                ++k ++e++++ + a++++ + + ++  k+++i+ l+   ++l
  EEA20540.1  8 LQKLVQEIESRAIVAQQQISIVKTQIATKQRDIRLLQLTSSEL 50
                7899******************************998776666 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.02
     DUF4200  87 aeietlkseiekleekleey 106
                 +e +tlk++i+ le++l  +
  EEA20540.1  81 SEDQTLKKDISDLEKRLHYL 100
                 44444444444444443322 PP

>> HMMR_N  Hyaluronan mediated motility receptor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   4.5   8.9e-05      0.11     202     300 ..       9     108 ..       5     116 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 8.9e-05
      HMMR_N 202 kakvaqLkeklvslekekieekseteklleyieelsnvseqlekykldiaqleellke.kndeiesLkssLeekeqelskqvkdlnekckllekekeel 299
                 ++ v++++ +    +++    k+++      i  l+ +s +l   ++d +++e + k   +  i  + s L+ ++q+l+k ++dl+++++ le+  e+ 
  EEA20540.1   9 QKLVQEIESRAIVAQQQISIVKTQIATKQRDIRLLQLTSSELGSLSKDTNVYEGVGKMfVQTPIDAVNSRLSSEDQTLKKDISDLEKRLHYLETTHEKS 107
                 666888888988888888889999999999999999999999999999999999988724667999***************************888843 PP

      HMMR_N 300 v 300
                  
  EEA20540.1 108 K 108
                 3 PP

>> T6PP_N  Trehalose-6-phosphate phosphatase N-terminal helical bundle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   3.6   0.00021      0.27      68      98 ..      85     115 ..       5     117 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00021
      T6PP_N  68 dikdEieeLekDlkFLefiqsdevenveqfl 98 
                  +k++i++Lek l++Le  +++++e++eq +
  EEA20540.1  85 TLKKDISDLEKRLHYLETTHEKSKEHIEQIF 115
                 47899999********************975 PP

>> ZapB  Cell division protein ZapB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.6      0.86   1.1e+03      38      40 ..      23      25 ..       6      59 .. 0.50
   2 ?   13.0   0.4   8.3e-05      0.11      27      65 ..      76     114 ..      73     116 .. 0.95

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.86
        ZapB 38 kee 40
                +++
  EEA20540.1 23 QQQ 25
                333 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 8.3e-05
        ZapB  27 ieeLkeeneelkeenreleeeneqlkeereawqerlkkL 65 
                 +++L  e ++lk+ +  le+ ++ l++++e+ +e+++++
  EEA20540.1  76 NSRLSSEDQTLKKDISDLEKRLHYLETTHEKSKEHIEQI 114
                 789*********************************986 PP

>> SlyX  SlyX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   2.5    0.0031         4       3      43 ..      10      50 ..       8      61 .. 0.87
   2 ?    4.4   0.1     0.044        57       3      20 ..      88     105 ..      86     114 .. 0.74

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0031
                HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        SlyX  3 erleeLEiklafqedtieeLndvvaeqqqqidrlqrqlrll 43
                + ++e+E++    +++i     ++a  q++i  lq    +l
  EEA20540.1 10 KLVQEIESRAIVAQQQISIVKTQIATKQRDIRLLQLTSSEL 50
                66899*****************************9766555 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.044
                 HHHHHHHHHHHHHHHHHH CS
        SlyX   3 erleeLEiklafqedtie 20 
                 + + +LE +l ++e t e
  EEA20540.1  88 KDISDLEKRLHYLETTHE 105
                 668888888888888765 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.4      0.13   1.7e+02       6      49 ..       8      51 ..       5      64 .. 0.79
   2 ?    8.5   0.7    0.0023         3      38      78 ..      76     116 ..      54     118 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.13
                HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        YabA  6 lfdkleeleeqleelleeleelkeelaelleenaeLeleneklr 49
                l + ++e+e++    +++++ +k+++a+   + + L+l  ++l 
  EEA20540.1  8 LQKLVQEIESRAIVAQQQISIVKTQIATKQRDIRLLQLTSSELG 51
                56678899999999999999999999998888888877777665 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0023
                 HHHHHHHHHHHHHHHXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        YabA  38 naeLeleneklrerleeeekkekekkkelsegkenLarlYe 78 
                 n++L+ e ++l++ +++ ek+ +  +++ +++ke+++++++
  EEA20540.1  76 NSRLSSEDQTLKKDISDLEKRLHYLETTHEKSKEHIEQIFR 116
                 88899999999999988888888888888888888888875 PP

>> Csm1_N  Csm1 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   1.4       0.2   2.5e+02      39      58 ..      22      41 ..       6      51 .. 0.63
   2 ?    1.1   0.1       0.4   5.2e+02      31      52 ..      28      49 ..      26      58 .. 0.72
   3 ?    8.6   1.1    0.0018       2.3      32      69 ..      79     109 ..      73     113 .. 0.56

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.2
      Csm1_N 39 kdqeiesLkeqlaeleekvk 58
                 +q+i+ +k q+a+ + +++
  EEA20540.1 22 AQQQISIVKTQIATKQRDIR 41
                46777777777777766655 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.4
      Csm1_N 31 vLsqkletkdqeiesLkeqlae 52
                + ++++ tk++ i  L+ +  e
  EEA20540.1 28 IVKTQIATKQRDIRLLQLTSSE 49
                5678889999999888866555 PP

  == domain 3  score: 8.6 bits;  conditional E-value: 0.0018
      Csm1_N  32 LsqkletkdqeiesLkeqlaeleekvkeleerrkkqeE 69 
                 Ls +        ++Lk+ +  le++++ le+ ++k++E
  EEA20540.1  79 LSSED-------QTLKKDISDLEKRLHYLETTHEKSKE 109
                 44444.......45555555555555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (120 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1531  (0.0853924); expected 358.6 (0.02)
Passed bias filter:                      761  (0.0424452); expected 358.6 (0.02)
Passed Vit filter:                        98  (0.005466); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.50u 0.31s 00:00:00.81 Elapsed: 00:00:00.48
# Mc/sec: 754.39
//
Query:       EEA20541.1  [L=187]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.2e-19   68.6  18.5    3.2e-19   68.6  18.5    1.6  2  Apq12     Nuclear pore assembly and biogenesis


Domain annotation for each model (and alignments):
>> Apq12  Nuclear pore assembly and biogenesis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.6  18.5   1.8e-23   3.2e-19       3      53 ..      68     118 ..      66     119 .. 0.97
   2 ?   -3.5   0.6      0.59     1e+04      39      44 ..     130     135 ..     130     138 .. 0.74

  Alignments for each domain:
  == domain 1  score: 68.6 bits;  conditional E-value: 1.8e-23
       Apq12   3 dlvsilllllilyvslkildrarRvvlfwvrllvrlvfwlavvlvgayvyn 53 
                 ++ sil+lll+ly+sl+ild+arRv++fwv+l+vrl+fw++vv++g+++yn
  EEA20541.1  68 NILSILTLLLTLYISLRILDYARRVIMFWVMLVVRLAFWATVVWLGIWIYN 118
                 689***********************************************9 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 0.59
       Apq12  39 vfwlav 44 
                 +fw++v
  EEA20541.1 130 WFWGVV 135
                 589887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (187 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       802  (0.044732); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.31s 00:00:00.78 Elapsed: 00:00:00.48
# Mc/sec: 1168.16
//
Query:       EEA20542.1  [L=310]
Description: ATP binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-74  251.0   0.0      4e-74  249.4   0.0    1.6  1  ATP_bind_1       Conserved hypothetical ATP binding protein
    0.00012   22.1   0.0     0.0003   20.8   0.0    1.7  1  AAA_14           AAA domain
    0.00041   20.8   0.0     0.0018   18.7   0.0    1.9  2  AAA_16           AAA ATPase domain
    0.00069   19.5   0.0     0.0014   18.5   0.0    1.5  1  CLP1_P           mRNA cleavage and polyadenylation factor CLP
     0.0014   19.1   0.0     0.0037   17.7   0.0    1.7  1  AAA              ATPase family associated with various cellul
     0.0016   17.6   0.0     0.0025   16.9   0.0    1.4  1  T2SSE            Type II/IV secretion system protein
     0.0022   18.3   0.0     0.0049   17.2   0.0    1.6  1  AAA_22           AAA domain
     0.0022   18.3   0.1      0.023   15.1   0.0    2.1  2  AAA_19           AAA domain
     0.0024   17.6   0.0     0.0047   16.7   0.0    1.5  1  AAA_24           AAA domain
     0.0035   17.9   0.0     0.0076   16.8   0.0    1.7  1  AAA_18           AAA domain
     0.0054   17.3   0.0       0.02   15.4   0.0    1.8  2  ABC_tran         ABC transporter
     0.0055   17.1   0.0      0.013   15.9   0.0    1.6  1  RNA_helicase     RNA helicase
      0.007   15.9   0.0      0.013   15.0   0.0    1.5  1  AAA_7            P-loop containing dynein motor region
  ------ inclusion threshold ------
      0.015   15.0   0.0      0.038   13.7   0.0    1.6  2  AAA_30           AAA domain
      0.017   15.0   0.0      0.029   14.3   0.0    1.4  1  ATPase_2         ATPase domain predominantly from Archaea
      0.019   15.0   0.0      0.033   14.2   0.0    1.4  1  TsaE             Threonylcarbamoyl adenosine biosynthesis pro
      0.019   14.9   0.0      0.033   14.1   0.0    1.3  1  NACHT            NACHT domain
      0.021   14.0   0.1      0.081   12.1   0.0    1.9  2  NB-ARC           NB-ARC domain
      0.025   14.7   0.0      0.037   14.2   0.0    1.4  1  AAA_33           AAA domain
      0.028   14.4   0.0      0.056   13.4   0.0    1.5  1  NTPase_1         NTPase
      0.034   13.9   0.0      0.092   12.5   0.0    1.7  1  AAA_29           P-loop containing region of AAA domain
      0.035   14.2   0.0      0.076   13.1   0.0    1.9  1  MMR_HSR1         50S ribosome-binding GTPase
      0.036   13.8   0.0      0.057   13.1   0.0    1.3  1  Sigma54_activat  Sigma-54 interaction domain
      0.039   13.2   0.0      0.066   12.5   0.0    1.3  1  Septin           Septin
      0.044   13.7   0.1       0.19   11.7   0.0    1.9  2  RsgA_GTPase      RsgA GTPase
      0.044   13.1   0.0      0.091   12.1   0.0    1.5  1  ATPase           KaiC
      0.054   13.1   0.0      0.095   12.3   0.0    1.4  1  SRP54            SRP54-type protein, GTPase domain
      0.055   13.1   0.1       0.24   11.0   0.0    1.9  2  cobW             CobW/HypB/UreG, nucleotide-binding domain
      0.074   12.7   0.0       0.18   11.4   0.0    1.6  1  Thymidylate_kin  Thymidylate kinase
      0.082   12.4   0.0          5    6.6   0.0    2.2  2  GTP_EFTU         Elongation factor Tu GTP binding domain
      0.086   12.8   0.0        5.4    6.9   0.0    2.2  1  AAA_31           AAA domain
      0.087   12.0   0.0      0.089   12.0   0.0    1.4  1  KAP_NTPase       KAP family P-loop domain
       0.11   12.2   0.0       0.38   10.5   0.0    1.8  2  PduV-EutP        Ethanolamine utilisation - propanediol utili
       0.13   12.7   0.0       0.37   11.2   0.0    1.7  1  AAA_17           AAA domain
       0.13   12.0   0.1       0.31   10.8   0.0    1.6  1  IstB_IS21        IstB-like ATP binding protein
       0.14   12.2   0.0       0.23   11.4   0.0    1.4  1  AAA_5            AAA domain (dynein-related subfamily)


Domain annotation for each model (and alignments):
>> ATP_bind_1  Conserved hypothetical ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  249.4   0.0     8e-77     4e-74       1     241 []       8     288 ..       8     288 .. 0.96

  Alignments for each domain:
  == domain 1  score: 249.4 bits;  conditional E-value: 8e-77
  ATP_bind_1   1 vvGpaGsGKttfvgalseilelrgrsvavvNLDPAaeelpYeaavdirelitledvmedlglgpngalvvaleflresldwldeeleke.eddyllfDt 98 
                 v+GpaG+GKttf++a++++l+++ rs+ +vNLDPAae+++Y++++direlitledvme+l+lgpng+l++++efl+++ld l e+l+   e+ +++fD+
  EEA20542.1   8 VMGPAGAGKTTFCNAIIQHLQNTRRSCFYVNLDPAAESFQYNPDLDIRELITLEDVMEELELGPNGGLIYCFEFLMQNLDFLTEALDPLsEEYLIIFDM 106
                 89************************************************************************************7775557889*** PP

  ATP_bind_1  99 PGQielfthseslakiveeLes....efalvvvyLvDsqrltdptkfisgllsalsamlrlelPhvvvlnkfDllkek.lekeleffedvealslllek 192
                 PGQiel+th + l  +++ L++    +++l++ yL++s+++ d +kf+ g+lsa+sam+ le+Ph+++l+k+D +k+   +++l++f +v+ ++ll e+
  EEA20542.1 107 PGQIELYTHIPLLPTLTNFLSRqgplNINLCAAYLLESTFVIDKAKFFAGTLSAMSAMILLEMPHINILSKMDQVKDMvGRRRLKRFINVD-VQLLDED 204
                 ********************98889999************************************************889999******995.5555555 PP

  ATP_bind_1 193 ee....................................ekykklaeaiaelleefalvlrflplssekeesiedllslidealqe 241
                 ++                                    + +++l++a+ +l+++f++v +fl+l++++e+s+ ++ls+id+a+q+
  EEA20542.1 205 DNadgkapktitqddddieaqeqdvrvdpsskgelmsgGSFNRLNKAVGQLIDDFSMV-SFLQLDVSDEDSVGAILSYIDDAIQY 288
                 55699*********************************99******************.***********************996 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8   0.0   6.1e-07    0.0003       5      51 ..       6      53 ..       3     105 .. 0.80

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 6.1e-07
      AAA_14  5 lvitGaRrvGKTtllkqlikellvkkesilyinldderdkkladpe.k 51
                ++++G+  +GKTt+++ +i++l  +++s++y+nld   ++ + +p+ +
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQNTRRSCFYVNLDPAAESFQYNPDlD 53
                6899***************999999**********9877444444432 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   3.6e-06    0.0018      27      88 ..       6      70 ..       3     132 .. 0.82
   2 ?   -0.6   0.0         3   1.5e+03      97     129 ..     218     258 ..     174     280 .. 0.61

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 3.6e-06
      AAA_16 27 vllsGesGvGKsslvrellralekdggiflrgkcdqlesaipy...salaqalareellrqllde 88
                vl+ G++G GK++  +++ ++l+ ++  +++ + d   ++  y   + + ++++ e+++++l+  
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQNTRRSCFYVNLDPAAESFQYnpdLDIRELITLEDVMEELELG 70
                9**********************998888888888887777777756688888888888877665 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 3
      AAA_16  97 wrekleealaavpelagaea............srllellkrllal 129
                 +++ +e++ ++v+ +    +            +rl+ ++ +l++ 
  EEA20542.1 218 DDDDIEAQEQDVRVD----PsskgelmsggsfNRLNKAVGQLIDD 258
                 222222222222222....02223555666678888888888843 PP

>> CLP1_P  mRNA cleavage and polyadenylation factor CLP1 P-loop
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.0   2.8e-06    0.0014       1      37 [.      10      46 ..      10      49 .. 0.91

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 2.8e-06
      CLP1_P  1 GpkdsGKSTlarlLlNyalrkgrkpvyvDlDvGqsei 37
                Gp  +GK+T++  +++ + +  r++ yv+lD+   ++
  EEA20542.1 10 GPAGAGKTTFCNAIIQHLQNTRRSCFYVNLDPAAESF 46
                8999*************999999999******98776 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0   7.4e-06    0.0037       1      32 [.       6      40 ..       6      65 .. 0.74

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 7.4e-06
                EEEESSTTSSHHHHHHHHHHHHT...HEEEEEETT CS
         AAA  1 vllyGppGtGKTllakavakelg...vefleisgs 32
                vl++Gp G GKT++++a++++l+   ++++ +++ 
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQntrRSCFYVNLD 40
                799******************96444556666555 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.0     5e-06    0.0025     129     158 ..       3      32 ..       1      65 [. 0.85

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 5e-06
       T2SSE 129 rglilvsGgTgsGKttllyallkeinksde 158
                 +  +lv G+ g GKtt+ +a+++ ++++ +
  EEA20542.1   3 KFGVLVMGPAGAGKTTFCNAIIQHLQNTRR 32 
                 5669*********************98843 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   9.8e-06    0.0049       9      50 ..       7      42 ..       3      93 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 9.8e-06
      AAA_22  9 vvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpss 50
                +v+G++G+GKTt ++ + + l++       r+++++v+l   
  EEA20542.1  7 LVMGPAGAGKTTFCNAIIQHLQNT------RRSCFYVNLDPA 42
                79*******************886......888888887655 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   4.5e-05     0.023      13      38 ..       6      31 ..       2      45 .. 0.88
   2 ?    0.9   0.0       1.1   5.4e+02      99     119 ..     247     267 ..     135     274 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 4.5e-05
      AAA_19 13 llvtaGpGtGKTrvlkhivallvelg 38
                +lv++++G GKT+  ++i+++l++++
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQNTR 31
                799*******************9987 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 1.1
      AAA_19  99 klqeeellivDEfqdvdelqy 119
                  l+++   ++D f++v+ lq 
  EEA20542.1 247 RLNKAVGQLIDDFSMVSFLQL 267
                 453444568999999998775 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   9.4e-06    0.0047       5      56 ..       6      67 ..       2     105 .. 0.84

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 9.4e-06
      AAA_24  5 iliyGpsgiGKTtlakel.......gpkplfidtekGlksldadkfpdie...swedfldev 56
                +l++Gp+g+GKTt+++ +         + ++++++  + s + +   di+   ++ed+++e+
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIiqhlqntRRSCFYVNLDPAAESFQYNPDLDIReliTLEDVMEEL 67
                89****************9*99999999999*****99999999999999666666666654 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.0   1.5e-05    0.0076       1      25 [.       6      40 ..       6     113 .. 0.72

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 1.5e-05
      AAA_18  1 IlltGtpGvGKttlakeLskrlgf..........g 25
                +l++G++G+GKtt+++++ ++l++           
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQNtrrscfyvnlD 40
                79****************88874435555533330 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   4.1e-05      0.02      14      39 ..       6      31 ..       4      56 .. 0.89
   2 ?   -1.4   0.0         6     3e+03      93      93 ..     223     223 ..     163     257 .. 0.54

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 4.1e-05
                EEEEESTTSSHHHHHHHHTTSS--SE CS
                xxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran 14 vaivGenGaGKStLlkllagllkpte 39
                v ++G+ GaGK+t++++++++l++t 
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQNTR 31
                5689****************999875 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 6
                 T CS
                 x RF
    ABC_tran  93 g 93 
                 +
  EEA20542.1 223 E 223
                 1 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   2.5e-05     0.013       1      36 [.       6      37 ..       6      54 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 2.5e-05
  RNA_helicase  1 iwlyGpsgeGKStlakeLakallkklklkkkdsvys 36
                  +++ Gp+g GK+t+++ ++++l+++    +++ +y+
    EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQNT----RRSCFYV 37
                  5799*************99998844....3455554 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   2.7e-05     0.013      33      75 ..       3      45 ..       1      53 [. 0.86

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 2.7e-05
       AAA_7 33 kkpvllvGptGtGKtviikdllkkldkekylsltinfsaqtsa 75
                k  vl++Gp+G GKt+ ++ ++++l++++ ++  +n+    ++
  EEA20542.1  3 KFGVLVMGPAGAGKTTFCNAIIQHLQNTRRSCFYVNLDPAAES 45
                5679**********************99999999998766655 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   7.7e-05     0.038      21      46 ..       6      31 ..       2      45 .. 0.84
   2 ?   -2.7   0.0       8.2   4.1e+03      86     105 ..     248     267 ..     224     268 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 7.7e-05
      AAA_30 21 avltGpAGtGKttalkalreaweaag 46
                +++ GpAG+GKtt  +a+ +++++  
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQNTR 31
                5789**************99988765 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 8.2
      AAA_30  86 lepgtllivDEagmvdtkql 105
                 l+++   ++D  +mv++ ql
  EEA20542.1 248 LNKAVGQLIDDFSMVSFLQL 267
                 55555668999999998776 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   5.9e-05     0.029      23      58 ..       6      40 ..       2      93 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 5.9e-05
    ATPase_2 23 yfiYGpegsGKtaLlkeiienledkdkyviyyialr 58
                +++ Gp g GKt++ + ii+ l++      +y +l 
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQNTRR-SCFYVNLD 40
                6899******************88665.56665554 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   6.5e-05     0.033      22      45 ..       6      29 ..       1      37 [. 0.86

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 6.5e-05
                EEEEESTTSSHHHHHHHHHHHTT- CS
        TsaE 22 ilLeGdLGaGKTtlvrglakalgv 45
                +l  G+ GaGKTt++ +++++l+ 
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQN 29
                7889****************9975 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   6.6e-05     0.033       3      28 ..       6      31 ..       5      50 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 6.6e-05
                EEEEC-TTTCHHHHHHHHHHHHCTS- CS
       NACHT  3 vilqGeaGsGKTtLlqklalawaegk 28
                v++ G+aG GKTt+   +++ ++  +
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQNTR 31
                7899****************999876 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   0.00016     0.081      22      51 ..       5      35 ..       1      39 [. 0.86
   2 ?   -1.6   0.0       2.4   1.2e+03      46      82 ..     254     292 ..     246     303 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00016
                EEEEEESTTSSHHHHHHHHCCSHCCCCC.CB CS
      NB-ARC 22 vvalvGmgGvGKttlakqilnksdeveg.rF 51
                 v ++G +G GKtt  + i+++++++++ +F
  EEA20542.1  5 GVLVMGPAGAGKTTFCNAIIQHLQNTRRsCF 35
                58899*****************999988666 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 2.4
                 CCCCCBT..EEEEEEEESXXHHHHHHHXXHHHHHCCCTT CS
      NB-ARC  46 evegrFd..svawvvvsktdkseeiletilkeLslsedd 82 
                 +++  F   s+ ++ vs++d+   il  i   ++ +e++
  EEA20542.1 254 QLIDDFSmvSFLQLDVSDEDSVGAILSYIDDAIQYNEAQ 292
                 555666644567889999999999999999888777555 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   7.5e-05     0.037       2      35 ..       6      44 ..       6     107 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 7.5e-05
      AAA_33  2 vllvGlpGsGKstlaerllkklg.....avllssdtlrr 35
                vl+ G++G+GK+t+   ++++l+     ++ ++ d + +
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQntrrsCFYVNLDPAAE 44
                7899*************9999987788855555555444 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   0.00011     0.056       2      26 ..       6      30 ..       5      38 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 0.00011
                EEEE--TTSSHHHHHHHHHHHH... CS
    NTPase_1  2 vfiTGppGvGKtTlvkkvlellkss 26
                v++ Gp G GKtT+++ +++ l++ 
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQNT 30
                6899******************754 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   0.00019     0.092      23      47 ..       5      28 ..       1      36 [. 0.81

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00019
      AAA_29 23 gatlltGpsGsGKSTllDAiqalLv 47
                g +l++Gp G+GK+T+  Ai+  L 
  EEA20542.1  5 G-VLVMGPAGAGKTTFCNAIIQHLQ 28
                4.89**************9987665 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   0.00015     0.076       2      55 ..       6     108 ..       5     227 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 0.00015
                 EEEEESTTSSHHHHHHHHHTSTEEE.SSSTTSSSSEEEEEEEETTEE.................................................EEE CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltgekaiv.sdkpgtTrdinegrvklkgke.................................................iel 50 
                 v+++G   +GK+t+ na+++    +  +   + +d+  + ++++  +                                                 +++
  EEA20542.1   6 VLVMGPAGAGKTTFCNAIIQHLQNTrRSCFYVNLDPAAESFQYNP-DldirelitledvmeelelgpnggliycfeflmqnldfltealdplseeyLII 103
                 789****************98555514444566777666666332.13455555555566666666666666666666666666666666666666667 PP

                 EECGG CS
    MMR_HSR1  51 vDtpG 55 
                  D+pG
  EEA20542.1 104 FDMPG 108
                 77777 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   0.00011     0.057      23      58 ..       4      39 ..       1      52 [. 0.77

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 0.00011
                     S-EEEECSTTSSHHHHHHHHHHHSTTTTS-EEEEET CS
  Sigma54_activat 23 lsvlitGesGtGKellaraiheaskrkekpfvavnc 58
                       vl++G  G+GK+++ +ai ++ ++++++   vn 
       EEA20542.1  4 FGVLVMGPAGAGKTTFCNAIIQHLQNTRRSCFYVNL 39
                     679*****************8877766666666654 PP

>> Septin  Septin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   0.00013     0.066       4      32 ..       3      31 ..       2      68 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00013
                EEEEEEEEBTTSSCCCCCCTTSSSS---- CS
      Septin  4 eftlmvvGesglGkttlintlfetdliee 32
                +f ++v+G  g Gktt+ n+++++   ++
  EEA20542.1  3 KFGVLVMGPAGAGKTTFCNAIIQHLQNTR 31
                699*****************998755444 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00037      0.19     102     124 ..       6      28 ..       2      34 .. 0.85
   2 ?   -1.2   0.0       3.3   1.6e+03      50      80 ..     172     201 ..     159     217 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00037
                  EEEECSTTSSHHHHHHHHCTT-- CS
  RsgA_GTPase 102 svlvGqSGvGKStLinallpele 124
                  ++++G+ G+GK+t+ na++++l+
   EEA20542.1   6 VLVMGPAGAGKTTFCNAIIQHLQ 28 
                  5689**************99865 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 3.3
                  EEEEE-GGG--HHHHHHHHHHHHHHTTSEEE CS
  RsgA_GTPase  50 vivlnKiDlleeeeeleelkeelealgyevl 80 
                  + +l+K+D ++++   ++  +++ ++++++l
   EEA20542.1 172 INILSKMDQVKDMV-GRRRLKRFINVDVQLL 201
                  44799999999998.6666666666665554 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   0.00018     0.091      22      66 ..       6      49 ..       2      59 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00018
      ATPase 22 vlitGepGtGKtifalqFlikgaekygepgvfvtveepaedlren 66
                vl++G +G+GKt+f+   +i+ ++++ + + +v ++  ae+++ n
  EEA20542.1  6 VLVMGPAGAGKTTFCNA-IIQHLQNTRRSCFYVNLDPAAESFQYN 49
                89*************98.7778888899********999988765 PP

>> SRP54  SRP54-type protein, GTPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   0.00019     0.095       4      38 ..       6      40 ..       3      43 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00019
                EEEEESTTSSHHHHHHHHHHHHHHTTS-EEEEEES CS
       SRP54  4 illvGlqGaGKTttlaKLaallkkegkkvllvaaD 38
                +l++G+ GaGKTt +  + ++l++  +++  v +D
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQNTRRSCFYVNLD 40
                799*********************99999888777 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00049      0.24       4      26 ..       7      29 ..       5      38 .. 0.81
   2 ?   -0.9   0.0       2.1   1.1e+03     133     157 ..     161     185 ..     138     200 .. 0.67

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00049
                EEEESTTCCHHHHHHHHHCT--S CS
        cobW  4 vltGflGsGKTtLlnhllenrag 26
                ++ G+ G+GKTt+ n+++++ ++
  EEA20542.1  7 LVMGPAGAGKTTFCNAIIQHLQN 29
                689***************66544 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 2.1
                 HHHHHHHHTSSEEEEE-HHHHCHC. CS
        cobW 133 ekaedqlaaadllvlnKtDlldeea 157
                   a   l++  + +l+K+D++++  
  EEA20542.1 161 MSAMILLEMPHINILSKMDQVKDMV 185
                 4555566777778999999999873 PP

>> Thymidylate_kin  Thymidylate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00037      0.18       3      27 ..      10      35 ..       8      45 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00037
                     ESTTSSHHHHHHHHHHHHHHTTE..E CS
  Thymidylate_kin  3 GlDGaGKttqaellkerlkeegik.v 27
                     G  GaGKtt+++++ ++l++  ++  
       EEA20542.1 10 GPAGAGKTTFCNAIIQHLQNTRRScF 35
                     677****************9988744 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   0.0      0.01         5       6      30 ..       6      30 ..       3      37 .. 0.87
   2 ?    3.8   0.0     0.074        37     112     150 ..     158     201 ..     147     287 .. 0.71

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.01
                EEEEESTTSSHHHHHHHHHHHTTSS CS
    GTP_EFTU  6 igiighvDhGKtTLtdrLlyktgai 30
                + ++g   +GKtT++ +++++++++
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQNT 30
                6899***************988765 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.074
                 HHHHHHHHHTTTEEEEEEESCGST.....HHHHHHHHHHHHHHH CS
    GTP_EFTU 112 eevlrlalkegvpiivfiNKmDrl.....kaelkeiveevkqkl 150
                    +  ++ +++p i ++ KmD++     + +lk+ ++   q l
  EEA20542.1 158 LSAMSAMILLEMPHINILSKMDQVkdmvgRRRLKRFINVDVQLL 201
                 566778888999************77776555555555444444 PP

>> AAA_31  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.0     0.011       5.4     100     133 ..      82     114 ..      10     121 .. 0.46

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.011
      AAA_31 100 lekkeeilkellekvkdeYDyiiiDcpPsLgllt 133
                 l+++ + l+e+l+ +++eY +ii+D+p +++l+t
  EEA20542.1  82 LMQNLDFLTEALDPLSEEY-LIIFDMPGQIELYT 114
                 2333445566666666666.56666666666665 PP

>> KAP_NTPase  KAP family P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   0.00018     0.089      23      83 ..       6      66 ..       2     295 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00018
  KAP_NTPase 23 vgLygkWGsGKssllnkledelkefakpvrflfaefnaw..sfkggddavaellaaLadalee 83
                v + g+ G+GK++++n +++ l++    ++ + ++++++  sf+++ d++ + l +L d++ee
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQHLQNT--RRSCFYVNLDPAaeSFQYNPDLDIRELITLEDVMEE 66
                5666777******************..888888999988333455555555555555555555 PP

>> PduV-EutP  Ethanolamine utilisation - propanediol utilisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00077      0.38       4      23 ..       6      25 ..       2      39 .. 0.88
   2 ?   -2.3   0.0       6.6   3.3e+03      87     104 ..     166     183 ..     150     191 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00077
   PduV-EutP  4 illiGkvgsGKttLtqalkg 23
                +l++G+ g+GKtt ++a+ +
  EEA20542.1  6 VLVMGPAGAGKTTFCNAIIQ 25
                89*************99855 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 6.6
   PduV-EutP  87 vfnkeviGiitkidlaed 104
                 +++ + i i+ k+d ++d
  EEA20542.1 166 LLEMPHINILSKMDQVKD 183
                 456788999999999876 PP

>> AAA_17  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   0.00073      0.37       2      20 ..      10      28 ..       9      33 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00073
                E-TTSSHHHHHHHHHHHHT CS
      AAA_17  2 GgPGsGKgtqceklvekyg 20
                G+ G+GK+t c+ + ++++
  EEA20542.1 10 GPAGAGKTTFCNAIIQHLQ 28
                99*************9986 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00062      0.31      49      84 ..       5      40 ..       2      54 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00062
   IstB_IS21 49 nivllGpsGvGKshlaialgveavraglsvlfvrve 84
                +++++Gp+G+GK+ +  a+ ++  ++  s ++v ++
  EEA20542.1  5 GVLVMGPAGAGKTTFCNAIIQHLQNTRRSCFYVNLD 40
                6899****************9999999999998775 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00047      0.23       1      36 [.       5      43 ..       5     113 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00047
                EEEEE--SSSSHHHHHHHGGGGB...S--EEEEE--TT- CS
       AAA_5  1 dvlLvGppGtgKselaerlaaal...nreveyvqltrdt 36
                +vl+ Gp G gK+++   + + l   +r+ +yv+l    
  EEA20542.1  5 GVLVMGPAGAGKTTFCNAIIQHLqntRRSCFYVNLDPAA 43
                5899*******************9999999999987655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (310 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       583  (0.0325172); expected 358.6 (0.02)
Passed bias filter:                      501  (0.0279436); expected 358.6 (0.02)
Passed Vit filter:                       118  (0.00658152); expected 17.9 (0.001)
Passed Fwd filter:                        36  (0.00200792); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              36  [number of targets reported over threshold]
# CPU time: 0.56u 0.31s 00:00:00.87 Elapsed: 00:00:00.46
# Mc/sec: 2013.80
//
Query:       EEA20543.1  [L=389]
Description: S-adenosylmethionine synthetase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.5e-67  224.0   0.4    2.2e-66  222.1   0.1    1.9  2  S-AdoMet_synt_C  S-adenosylmethionine synthetase, C-terminal 
      8e-44  148.4   0.8    1.3e-43  147.7   0.1    1.7  2  S-AdoMet_synt_N  S-adenosylmethionine synthetase, N-terminal 
    1.5e-43  147.8   0.0      3e-43  146.9   0.0    1.5  1  S-AdoMet_synt_M  S-adenosylmethionine synthetase, central dom


Domain annotation for each model (and alignments):
>> S-AdoMet_synt_C  S-adenosylmethionine synthetase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.1      0.18   1.1e+03      62     100 ..     177     214 ..     170     236 .. 0.46
   2 !  222.1   0.1   3.7e-70   2.2e-66       1     138 []     246     383 ..     246     383 .. 1.00

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.18
                      EEEEEEEE-TT-SS-SEEEEEE-S-BSS-HHHHHHHHHH CS
  S-AdoMet_synt_C  62 kvevqlsYaigvaepvsisvetfgtekvseeeiaeivke 100
                      +v+++ ++  g  +p+ +    +  +  se+  +e+v++
       EEA20543.1 177 QVTIEYAHDNGAVKPLRVDTVVISAQ-HSEDVTTETVRK 214
                      34444444456666664432222221.122222222222 PP

  == domain 2  score: 222.1 bits;  conditional E-value: 3.7e-70
                      S-TTTTS-EETTS-TTTTTTTTSS---S---TTB-TTSHHHHHHHHHHHHHHHHHHTTSBSEEEEEEEE-TT-SS-SEEEEEE-S-BSS-HHHH CS
  S-AdoMet_synt_C   1 iGgpkgdaGltgrkiivdtYgglaahgggafsgKdptkvDrsaayaaryvaknlvaaglakkvevqlsYaigvaepvsisvetfgtekvseeei 94 
                      iGgp+gdaGltgrkiivdtYgg++ahgggafsgKd++kvDrsaay+ar++ak+lv+a+la++ +vqlsYaigvaep+si+vet+gt++ s++e+
       EEA20543.1 246 IGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYSKVDRSAAYVARWIAKSLVNAKLARRALVQLSYAIGVAEPLSIFVETYGTSEKSSDEL 339
                      8********************************************************************************************* PP

                      HHHHHHH----HHHHHHHHTTTSS--TGGGSS-SSS--T-TTS. CS
  S-AdoMet_synt_C  95 aeivkevfdlrpaaiieeldLkkpiykktaayghfgreelpwek 138
                      ++i++++fdlrp+ i++eldL kpiy +ta++ghf++++++wek
       EEA20543.1 340 VKIIRDNFDLRPGVIVKELDLAKPIYFQTAKNGHFTNQDFAWEK 383
                      *******************************************7 PP

>> S-AdoMet_synt_N  S-adenosylmethionine synthetase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  147.7   0.1   2.1e-47   1.3e-43       2      99 .]      12     109 ..      11     109 .. 0.99
   2 ?   -2.7   0.1       1.7     1e+04      49      55 ..     197     203 ..     170     224 .. 0.50

  Alignments for each domain:
  == domain 1  score: 147.7 bits;  conditional E-value: 2.1e-47
  S-AdoMet_synt_N   2 ylftsesVseGHPDkvadqisdaildailkedpkarvacetlvttglvvvageittkakvdiekivrevikeigYekeelgfdaktcevlvale 95 
                      +lftsesV eGHPDk+adq+sda+lda+l+edp ++vacet+++tg+v+v+geittkak+d++ki+r +i++igY+++++gfd+ktc+vlva+e
       EEA20543.1  12 FLFTSESVGEGHPDKIADQVSDAVLDACLAEDPLSKVACETATKTGMVMVFGEITTKAKLDYQKIIRGAIQDIGYDDSSKGFDYKTCNVLVAIE 105
                      89******************************************************************************************** PP

  S-AdoMet_synt_N  96 eqsp 99 
                      +qsp
       EEA20543.1 106 QQSP 109
                      ***7 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 1.7
  S-AdoMet_synt_N  49 vvvagei 55 
                      vv+ ++ 
       EEA20543.1 197 VVISAQH 203
                      3333333 PP

>> S-AdoMet_synt_M  S-adenosylmethionine synthetase, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  146.9   0.0   5.1e-47     3e-43       2     120 .]     124     244 ..     123     244 .. 0.96

  Alignments for each domain:
  == domain 1  score: 146.9 bits;  conditional E-value: 5.1e-47
  S-AdoMet_synt_M   2 igAgDqGimfGYAtdeteelmPlpillahklaerlaelrkegeleylrpDaKsqvtveYee...elkpvrvdtvvistqhdeevsqeklredlk 92 
                      +gAgDqGimfGYAtdet+el+Pl++ll+hkl ++++e r +g+l+++rpD+K+qvt+eY +   + kp+rvdtvvis+qh+e+v++e++r++l 
       EEA20543.1 124 LGAGDQGIMFGYATDETPELLPLTLLLSHKLNRTMKEGRLDGTLPWVRPDTKTQVTIEYAHdngAVKPLRVDTVVISAQHSEDVTTETVRKELL 217
                      7**********************************************************5456799**************************** PP

  S-AdoMet_synt_M  93 ekvikkvlkeelldekktkllinptGkF 120
                      ekvikk++++elld++ t ++++p+G F
       EEA20543.1 218 EKVIKKAIPAELLDDR-TVYHLQPSGLF 244
                      ***********99885.*********88 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (389 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       483  (0.0269396); expected 358.6 (0.02)
Passed bias filter:                      439  (0.0244855); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.69u 0.33s 00:00:01.02 Elapsed: 00:00:00.58
# Mc/sec: 2029.32
//
Query:       EEA20544.1  [L=962]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   8.2e-162  539.7  18.9   8.2e-162  539.7  18.9    2.0  2  SLD3      DNA replication regulator SLD3


Domain annotation for each model (and alignments):
>> SLD3  DNA replication regulator SLD3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  539.7  18.9  4.6e-166  8.2e-162       2     539 .]     287     815 ..     286     815 .. 0.90
   2 ?   -6.4   8.2         1   1.8e+04     454     539 .]     873     946 ..     858     946 .. 0.61

  Alignments for each domain:
  == domain 1  score: 539.7 bits;  conditional E-value: 4.6e-166
                 HHHHHHHHHHHHHHSTTS-HHHHHHTHHHHHHHHHHHHHHTTTHHHHHHHHHHTT---HHHHHHHHTGGGS--SSHH...............HHHHHHH CS
        SLD3   2 ilenlrtqYleaLYssktsLaYFaKgpLsRaRaafqldlesnlemsdliefLrsliLstkeiDkKYretlpeviselktevedsdegskkkkkkkkkkk 100
                 i+enlrtqYle+LY+skts+aYFaKgpL+R+R+af  +++++ +   l++ +r+ iLs+k++D KYretlp ++++++   +d de+  +k k+k+kkk
  EEA20544.1 287 IMENLRTQYLETLYISKTSVAYFAKGPLTRCRNAFA-QYSPKEDVPSLSSQYRESILSVKKMDAKYRETLPVILRNMALLLSD-DER--PK-KRKSKKK 380
                 689*********************************.9***************************************999999.777..78.9****** PP

                 HHHHHTTT-TT--......................HHHHHHHHHHHHHHHHHHHHHHHHHHHHHT.........T-GGGGS------------------ CS
        SLD3 101 klgkngLypeeeelirkWwkarddekkvs.seesreeeikkhisdLrvREtqLQiiliLEilaLeekssekqlpglekkkkakekkkeekekkqktkqk 198
                 klgkngLy++e+e+ +k+wk+r+  k+ +  ees++eeik+h+sdLr+REtqLQi+liLE+++Le    +  +p++e +k ++             +++
  EEA20544.1 381 KLGKNGLYTGEDEFLQKYWKSRQVSKNKEgLEESKDEEIKRHVSDLRLRETQLQILLILETIHLE---LTTVTPSIEDSKGQEIG----------GSST 466
                 **********************777777779**********************************...32333444443333332..........3455 PP

                 ----------HHHHHHHHHHHHHHHHHHHHT-...-----------SHHTT-TTSTTSHHHHHHHTHHHHHSSSSHHHHHHHHHHHCXX.......... CS
        SLD3 199 kkkkkkkkqnlpvlLdvllDRLcIWqsvlsdevkalaesqkleeeeeaesakkaesdslrdFcvdViiPFfsaRLPelcksinrKlggpvakspkkkkk 297
                 k++k+kk++nl++lL++++DRLcIW++++  e  ++aes k +++++  s+kk esd+lrdFc++ViiPF+++RLPe+ck+i++Klgg ++ sp++++ 
  EEA20544.1 467 KRSKSKKEENLNLLLELFIDRLCIWHAISAGE-GVIAESLKETTNNHL-SGKKIESDALRDFCNEVIIPFYASRLPEQCKTIKKKLGGASEVSPSRPAP 563
                 678*****************************.999999986666555.9********************************************99977 PP

                 ...........XXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXX....XXXXXXXXXXXXXXXXXXX............. CS
        SLD3 298 skeksks....kakpgaa.akrsasqkekrrtlervltdekrsrrsvsrgpssaialsrsatatsipglkResseppllslisksesgllkskslkere 391
                 + ++s+s    k++ g a +k++++q+++rr l+rvltde+ s ++ sr+ps    l+rs+t+++++++kRes+ep+l+sl  + + g++ ++++++re
  EEA20544.1 564 KLKASTSasglKNQFGVAnSKKTQPQQKPRRMLQRVLTDEQISVSQRSRHPS----LLRSSTTPALQEVKRESVEPSLPSLGGSVRGGIQIARRVDKRE 658
                 7663333123355556555777777***************977777666665....************************9988888************ PP

                 ..XXXXXX.XXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.....XXXXXXXXXXXXXXXXXXXXXXXXXX............. CS
        SLD3 392 vdlsasasaeeakakkkaqv...eaeLkeaIsalrkPNRelvakeiveaaekrlsklqassrkskkpvrkplaqtvqVkATPkknrkkDvla....... 480
                 vdl+a a+ +eak+kk++++   ++eL++aI+alrkPNRelv+ke++++aekr+    +ssrksk+pvr+pl+q+vqV+ATP+++rkkD+         
  EEA20544.1 659 VDLNAAAKVHEAKLKKMNTLieqKKELDAAINALRKPNRELVSKEVADQAEKRTL---SSSRKSKNPVRNPLGQGVQVMATPRGTRKKDMSVehqsqps 754
                 **********************9******************************98...459*****************************999****** PP

                 ...................XXXXXXXXXXXXXXXXXXXXXXXXXXXXX.......XXXXXXXX. CS
        SLD3 481 .....kaeeesetaasaseetepaksssaqvvPsstlrksskekrknstssraeqsavqeTPsr 539
                       a  +s ++ + ++e++p+  s+ ++vP st+r+++ +++    +s+++ ++++eTPsr
  EEA20544.1 755 lprgpFARPSSIKQGEGADEASPELGSDISLVPGSTIRTNTLTSS---VTSKRKFNSITETPSR 815
                 ****955556668889999999****************9998777...5567899*******98 PP

  == domain 2  score: -6.4 bits;  conditional E-value: 1
                 XXXXXXXXXXXXXXXXX.XXXX....................XXXXXXXXXXXXXXXXXXXXXXXXXXXXX.......XXXXXXXX. CS
        SLD3 454 kpvrkplaqtvqVkATP.kknrkkDvlakaeeesetaasaseetepaksssaqvvPsstlrksskekrknstssraeqsavqeTPsr 539
                 ++  ++ ++t  ++ TP +kn+   +++    ++++ + +++ t+p+++      P ++++k++ + ++       + + vq+TP++
  EEA20544.1 873 NTDINSEDKTFSINQTPpAKNK---IFF----TQQQLSAPKAMTTPSSPVPGFETPIKAKPKQKVMPQD------DSAQVVQSTPVK 946
                 4444555677889999977777...554....3335567777788866666666666554433333332......446789999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (962 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       848  (0.0472977); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.77u 0.33s 00:00:01.10 Elapsed: 00:00:00.51
# Mc/sec: 5664.81
//
Query:       EEA20545.1  [L=734]
Description: nuclear localization protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.7e-52  176.8   1.0    3.5e-52  176.4   0.1    1.6  2  CRC_subunit  Chromatin remodelling complex Rsc7/Swp82 subunit
  ------ inclusion threshold ------
        5.3    7.3   8.9         19    5.6   8.9    2.0  1  AT_hook      AT hook motif


Domain annotation for each model (and alignments):
>> CRC_subunit  Chromatin remodelling complex Rsc7/Swp82 subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  176.4   0.1   3.9e-56   3.5e-52       3     135 .]     179     310 ..     177     310 .. 0.98
   2 ?   -3.2   0.1       1.1     1e+04      64     105 ..     490     531 ..     486     532 .. 0.78

  Alignments for each domain:
  == domain 1  score: 176.4 bits;  conditional E-value: 3.9e-56
  CRC_subunit   3 deykltkedpegekkidknGkLlggreyrvktFtleeregkklyvLstdlarllgfrdsylffkknpqllkllatqeekedLiergllpsslksrqik 100
                  dey  ++ d +ge+k+d +G L++gr yr++tF++++r g+kl++L+t++ar+lg+rdsyl+f+kn++l+k++a+q ek+dLi++++lp+s++srqi+
   EEA20545.1 179 DEYLAKEWDDAGETKVDMDGYLKDGRVYRCRTFRVPGR-GNKLFMLATECARVLGYRDSYLLFNKNRSLFKIIASQIEKDDLIQQDILPYSYRSRQIA 275
                  7899999*******************************.*********************************************************** PP

  CRC_subunit 101 lvtarsvFlefGariivkGkrvvDDYyeekakeqg 135
                  +vtars+F++fG+r+iv+G+rv DDY+e+ka++qg
   EEA20545.1 276 IVTARSMFRQFGSRVIVDGRRVRDDYWESKARKQG 310
                  *********************************98 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 1.1
  CRC_subunit  64 ffkknpqllkllatqeekedLiergllpsslksrqiklvtar 105
                  + ++++q + +la q++ + ++  +  ++s ++++ + vt +
   EEA20545.1 490 MNQTTQQHRGVLAGQQQAQLMTPPSQTAYSQQQQTASQVTVQ 531
                  556777778888889999999888888888888888888876 PP

>> AT_hook  AT hook motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   8.9    0.0021        19       2      11 ..      89      98 ..      88     100 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0021
     AT_hook  2 RkRGRPrKaa 11
                RkRGRP+K++
  EEA20545.1 89 RKRGRPPKTS 98
                9*******97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (734 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       621  (0.0346366); expected 358.6 (0.02)
Passed bias filter:                      249  (0.0138881); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.69u 0.30s 00:00:00.99 Elapsed: 00:00:00.52
# Mc/sec: 4218.62
//
Query:       EEA20546.1  [L=521]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-40  138.9  28.2    1.9e-40  138.9  28.2    1.7  2  MFS_1     Major Facilitator Superfamily
    1.3e-06   27.2   2.6    1.9e-06   26.6   2.6    1.2  1  TRI12     Fungal trichothecene efflux pump (TRI12)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.9  28.2   2.1e-44   1.9e-40       2     352 ..      63     471 ..      62     472 .. 0.81
   2 !    2.5   0.7    0.0064        57     122     186 ..     456     520 ..     454     521 .] 0.80

  Alignments for each domain:
  == domain 1  score: 138.9 bits;  conditional E-value: 2.1e-44
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlga 99 
                 +++++++++a+s+++p +   +a + +is  +  + +t++ +g+av+ ++l+++s+ +Gr++v++++++lf ++ l++++ + l+  +lv+r+++G+g+
  EEA20546.1  63 CISTLFASFAASCYSPGAE-QMAAEWHISQVACLIGITTFCAGFAVGPMFLAPFSEIIGRKPVFVATAILFMVCQLCCSV-TRLYgGMLVARFFAGIGG 159
                 58899**************.8****99999988888899***********************************888885.999999************ PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 +++ ++++ +iad++ +++r+  ++l+s+g+ +G+ lgpl+ g++ ++  Wr++fy+  i++ +  + +ll+++e++++      ++++          
  EEA20546.1 160 STFSTMVGGIIADIYLPRDRNTPMALFSGGALFGTGLGPLVCGFIGQYTTWRWIFYLQIIIGGIITLAVLLFFRETRKDVVLRQRAQRLnewyekleaa 258
                 ****************************************************************9996666666666665555555555999******* PP

       MFS_1 189 ..............................kgtgpaplvp........awkallkdpvlw.illialllfffgfsglltllplylqevlgls.....gl 243
                                               +  ++a++ +        ++ +l + pv++ + l+a+++++ ++++ l+ +pl + + +++s     + 
  EEA20546.1 259 gcygvkfpqpcgggkegrgidilrirwkiaADEERAGVGEmlrisltrPFLLLITEPVVFfFSLWAAFSWS-VLYINLSVIPLVFETNYDFSlsqanS- 355
                 ***************99999999999888844444444444344455557777777766567888888887.9999*******999999999665432. PP

       MFS_1 244 llaglllallalvgailallagrls.dr...lgr..rrrlllallllllaalglallavtssavllllvlvl....iGfglgfv.fpsllalasdlapp 331
                   + ++  +++l+++ ++++  + + +r   +++  + rl+++++  +l+ lgl+l+++ts   ++++v v+     ++g + v  + +++la+ ++  
  EEA20546.1 356 --IFTATCVGSLLAMTISIIQEKTAvHRrkhWNSvpEHRLYFSCVESTLLPLGLFLFGWTSQFQVHWIVPVIgvaiSTIGIFSVyLAVFNYLADTYH-- 450
                 ..222244444444444777777775555563326699**********************8888888855555453555555551555555555555.. PP

       MFS_1 332 eeagtasglfntagslggalg 352
                 ++a +a+++ +++++  g ++
  EEA20546.1 451 SYASSALAAQSFCRNMLGGIF 471
                 9**************666665 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.0064
       MFS_1 122 aigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspke 186
                 a++  s + ++   + pl++  l  +l++  +  +l+++++ + ++ +ll++  p  r+r+++++
  EEA20546.1 456 ALAAQSFCRNMLGGIFPLVSRQLFNHLSFGPAASLLGGIGAALTLVPWLLIFFGPEIRARSRHAK 520
                 66666677777778899999999999999999999999999999988888888888888877766 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.6   2.6   2.2e-10   1.9e-06      85     219 ..      99     234 ..      47     264 .. 0.79

  Alignments for each domain:
  == domain 1  score: 26.6 bits;  conditional E-value: 2.2e-10
       TRI12  85 tlwttgqavsilvmgrltdrfgrrpfvilthilglvgaivgctatkfntllaamtllgvaagpa.gasplfvgelmsnktkflgllivsipvvvtsgls 182
                 t +  g av  + +  +++ +gr+p+ ++t il +v  +    +  +  +l a  + g+           ++ ++   + +   + + s  ++  +gl+
  EEA20546.1  99 TTFCAGFAVGPMFLAPFSEIIGRKPVFVATAILFMVCQLCCSVTRLYGGMLVARFFAGIGGSTFsTMVGGIIADIYLPRDRNTPMALFSGGALFGTGLG 197
                 6788999*****************************99887777778889999988888654430334457778888899999999************* PP

       TRI12 183 pylgqrlaiqgswrwifyiyiitsaiavllivvwyyp 219
                 p +   +    +wrwify+ ii+  i  l +++++  
  EEA20546.1 198 PLVCGFIGQYTTWRWIFYLQIIIGGIITLAVLLFFRE 234
                 ************************9987777776654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (521 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       872  (0.0486363); expected 358.6 (0.02)
Passed bias filter:                      451  (0.0251548); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.46
# Mc/sec: 3376.16
//
Query:       EEA20547.1  [L=727]
Description: homeobox transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.7e-16   59.8   2.4    5.5e-16   58.2   2.4    1.9  1  Homeodomain  Homeodomain
    2.6e-05   24.0   0.8    6.9e-05   22.7   0.8    1.7  1  Homeobox_KN  Homeobox KN domain
  ------ inclusion threshold ------
        0.1   12.3   4.7       0.18   11.5   4.7    1.4  1  DUF4638      Domain of unknown function (DUF4638)


Domain annotation for each model (and alignments):
>> Homeodomain  Homeodomain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.2   2.4   9.1e-20   5.5e-16       3      57 .]      66     120 ..      65     120 .. 0.97

  Alignments for each domain:
  == domain 1  score: 58.2 bits;  conditional E-value: 9.1e-20
                  -SSSS-HHHHHHHHHHHHHSSS-SHHHHHHHHHHHTS-HHHHHHHHHHHHHHHHH CS
  Homeodomain   3 kRttftkeqleeLeklFeenrypsaeereeLAkklgLeerqVkvWFqNrRakekk 57 
                  +R ++tkeq+++Le+ F+ +++p++++++eLA +++L+  +V +WFqNrRak k+
   EEA20547.1  66 SRPRLTKEQVDTLEAQFQAHPKPNSNKKRELAVQTNLSLPRVANWFQNRRAKAKQ 120
                  58899************************************************97 PP

>> Homeobox_KN  Homeobox KN domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   0.8   1.2e-08   6.9e-05       7      39 ..      84     116 ..      81     117 .. 0.94

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 1.2e-08
  Homeobox_KN   7 hnPYPseedKeeLlkeTglsvkqitnWFINaRr 39 
                   +P P+ ++K+eL+ +T+ls   + nWF N R+
   EEA20547.1  84 AHPKPNSNKKRELAVQTNLSLPRVANWFQNRRA 116
                  5899**************************996 PP

>> DUF4638  Domain of unknown function (DUF4638)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   4.7   3.1e-05      0.18      31     143 ..     104     219 ..      92     247 .. 0.66

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 3.1e-05
     DUF4638  31 LtrvLeWLerrkGkkkqalqekekkvalskaeek.eekktkgikkkk....kgkrkvafseqlaselskkdaalyrrlyeveakgkrlslipssyards 124
                 L rv +W++ r+ k kq+++++e + ++ +a+ek ++ k+ + ++++    + ++k+ ++++  s+ ++k+++ ++  + ++ + +  +  +ss +r +
  EEA20547.1 104 LPRVANWFQNRRAKAKQQKRQEEFERMQREAKEKeDQSKSIKDEEQDyglpGCDQKSPIHKDDNSHGTTKSPTPTQASNYTKDRPQ--TSDSSSLSRPK 200
                 789***********999998666665555555551455555555555566555666666666666666565555544333222222..22356666666 PP

     DUF4638 125 arksdldikDaialestqr 143
                 ++k+  d+    +  s qr
  EEA20547.1 201 HQKTGSDLAQEKTYASLQR 219
                 6666666555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (727 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1667  (0.0929779); expected 358.6 (0.02)
Passed bias filter:                      616  (0.0343577); expected 358.6 (0.02)
Passed Vit filter:                        77  (0.00429472); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.78u 0.29s 00:00:01.07 Elapsed: 00:00:00.47
# Mc/sec: 4667.10
//
Query:       EEA20548.1  [L=245]
Description: glycerol-3-phosphate phosphatase (GppA), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.6e-22   79.8   0.0    3.3e-22   79.4   0.0    1.1  1  HAD_2        Haloacid dehalogenase-like hydrolase
    5.4e-10   39.9   0.2    3.7e-05   24.1   0.0    2.9  3  Hydrolase    haloacid dehalogenase-like hydrolase
      3e-07   31.0   0.0    4.1e-07   30.6   0.0    1.2  1  HAD          haloacid dehalogenase-like hydrolase
     0.0044   17.1   0.2       0.07   13.3   0.2    2.7  1  Hydrolase_6  Haloacid dehalogenase-like hydrolase


Domain annotation for each model (and alignments):
>> HAD_2  Haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.4   0.0   7.4e-26   3.3e-22       1     177 [.      21     199 ..      21     200 .. 0.81

  Alignments for each domain:
  == domain 1  score: 79.4 bits;  conditional E-value: 7.4e-26
       HAD_2   1 iiFDlDgTlldteeliiqafnelleeyglselseeel.rkliglslrellrklgeseeeeekieellrkyneekkk...kevkpydgvkelLeeLkeag 95 
                 ++FD+DgT++d++ +i++ ++el ee g+   ++e + ++  g  + ++l  + es+    ++e++ + ++  + +   +  + ++g+++lL++L +a+
  EEA20548.1  21 LLFDFDGTIIDSTAAIVKHWHELGEELGV---DPEAIlATSHGRRSIDTLALYDESKA---NWEFV-SAIEGALPRkygQDATEIPGARNLLKQLVDAN 112
                 69*************************88...45554044455556666666666544...55554.33333333334578999*************** PP

       HAD_2  96 yklgivTsksreaveekleqlgiesyFdvivtsedvekkKPdpeviekalekl......klkkeeviyvGDsptDieaakkagikvia 177
                 +  ++vTs++r+ ++  le l++ +  +  v++edv + KPdp++++    kl        ++ ++++v+D p++i+a+k+ag kv+a
  EEA20548.1 113 VPWAVVTSGTRALITGWLEVLKLAHP-KNLVVAEDVLQGKPDPQCYQLGRSKLssdvgfPSDSTNMLVVEDAPSGIKAGKAAGFKVLA 199
                 **********************9665.7778899999****************888877778889999*****************987 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.7   0.0     5e-05      0.23       3      37 ..      20      58 ..      18      93 .. 0.77
   2 !   24.1   0.0   8.3e-09   3.7e-05     119     210 .]      97     194 ..      89     194 .. 0.87
   3 ?    0.6   0.0      0.13     6e+02     122     138 ..     201     217 ..     197     218 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 5e-05
                EEEEESBTTTBCHHHHHHHHHHHH....CHHHHHHHHHH CS
                xxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxx RF
   Hydrolase  3 tvvfDkdGTLttgepsvedvivsa....alalaaaletg 37
                 ++fD+dGT+++++  +++ + ++     ++  a+l+t+
  EEA20548.1 20 GLLFDFDGTIIDSTAAIVKHWHELgeelGVDPEAILATS 58
                689***********9999999999665555555555555 PP

  == domain 2  score: 24.1 bits;  conditional E-value: 8.3e-09
                 BHTTHHHHHHHHHHTTEEEEEEESSEHHHHHHHHHHTTGGGESEEEEHHCESSTTTSHHHHHHHHHHHT......STGGGEEEEESSHHHHHHHHHTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase 119 vkpeaaeavasLkaagievvlltgdnpetaeraanqlGddyfdaviasdietvakpspegkvaaireLq......gkpeevamVGDgvnDaaalaaAg 210
                   p+a+ ++++L +a+++++++t++ ++     ++ l   + ++ + ++++  +kp+p++++    +L        +  ++++V+D + +++a++aAg
  EEA20548.1  97 EIPGARNLLKQLVDANVPWAVVTSGTRALITGWLEVLKLAHPKNLVVAEDVLQGKPDPQCYQLGRSKLSsdvgfpSDSTNMLVVEDAPSGIKAGKAAG 194
                 579************************88888887777444566666666679***************877778877999*****************8 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.13
                 THHHHHHHHHHTTEEEE CS
                 xxxxxxxxxxxxxxxxx RF
   Hydrolase 122 eaaeavasLkaagievv 138
                 e+ +++++Lk+ag +++
  EEA20548.1 201 ETTHTIQQLKDAGADWI 217
                 788**********9865 PP

>> HAD  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.6   0.0   9.2e-11   4.1e-07       2     130 ..      22     137 ..      21     166 .. 0.67

  Alignments for each domain:
  == domain 1  score: 30.6 bits;  conditional E-value: 9.2e-11
         HAD   2 lfDfDgTLldgdslelllrfllrrgaprlwralreklllal.....frellrldraglaelleallaglseelaaelerfvaevirpklldpgalella 95 
                 lfDfDgT++d+  ++  ++     + ++l+++l + ++++l      r++ +l   +  ++ +++ ++ +++l +  ++      ++  + pga+ ll+
  EEA20548.1  22 LFDFDGTIIDSTAAI--VK-----HWHELGEELGVDPEAILatshgRRSIDTLALYDESKANWEFVSAIEGALPRKYGQDA----TE--I-PGARNLLK 106
                 8**********4333..33.....344456666666666664444533444444447778888888888855544444444....22..5.9******* PP

         HAD  96 ahraaGdrvvvvSgglrplvepllaelgadevlat 130
                 +  +a+++ +vv++g r l+  +l+ l     la+
  EEA20548.1 107 QLVDANVPWAVVTSGTRALITGWLEVLK----LAH 137
                 999**********************999....665 PP

>> Hydrolase_6  Haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.3   0.2   1.6e-05      0.07       2      41 ..      22     123 ..      21     168 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.6e-05
                  EEESTTTSE..............................................................ETTEE-TTHHHHHHHHHHTT-EEEEEE CS
  Hydrolase_6   2 lfDidGvLw..............................................................rgdkaipgaaealnalraagkpvvllT 37 
                  lfD dG+++                                                              ++ + ipga ++l++l +a++p +++T
   EEA20548.1  22 LFDFDGTIIdstaaivkhwhelgeelgvdpeailatshgrrsidtlalydeskanwefvsaiegalprkygQDATEIPGARNLLKQLVDANVPWAVVT 119
                  7888888888888888888888888888888888888888888888888888888888888888888888889999********************** PP

                  ---S CS
  Hydrolase_6  38 Nnss 41 
                   +++
   EEA20548.1 120 SGTR 123
                  9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (245 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       351  (0.0195772); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1796.42
//
Query:       EEA20549.1  [L=549]
Description: GTP binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      1e-23   83.2  20.1      1e-23   83.2  20.1    1.9  1  GN3L_Grn1        GNL3L/Grn1 putative GTPase
    1.3e-18   67.1   0.3    1.1e-13   51.3   0.0    2.5  2  MMR_HSR1         50S ribosome-binding GTPase
    3.5e-07   30.3   0.0    2.8e-06   27.3   0.0    2.1  1  RsgA_GTPase      RsgA GTPase
    1.8e-05   24.3   0.0     0.0002   20.9   0.0    2.2  2  FeoB_N           Ferrous iron transport protein B
    7.8e-05   22.8   4.9       0.43   10.6   0.1    3.9  3  Dynamin_N        Dynamin family
    0.00019   21.0   1.2       0.47   10.0   0.0    3.1  3  GTP_EFTU         Elongation factor Tu GTP binding domain
     0.0036   16.7   0.0       0.16   11.3   0.0    2.3  2  AIG1             AIG1 family
  ------ inclusion threshold ------
      0.011   14.8   1.6      0.011   14.7   0.0    1.8  2  MeaB             Methylmalonyl Co-A mutase-associated GTPase 
      0.039   14.3   1.3         11    6.4   0.6    2.4  2  Nuc_deoxyri_tr2  Nucleoside 2-deoxyribosyltransferase like
      0.052   14.1   0.0      0.052   14.1   0.0    2.7  3  AAA_18           AAA domain
      0.094   12.9   0.0         22    5.3   0.0    2.5  2  Roc              Ras of Complex, Roc, domain of DAPkinase
        0.2   11.5   0.0       0.68    9.8   0.0    1.9  1  DUF2574          Protein of unknown function (DUF2574)
       0.22   11.3   0.9        4.2    7.2   0.0    2.8  2  NOG1             Nucleolar GTP-binding protein 1 (NOG1)
       0.83   10.0   0.0       0.83   10.0   0.0    3.1  1  AAA_16           AAA ATPase domain


Domain annotation for each model (and alignments):
>> GN3L_Grn1  GNL3L/Grn1 putative GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.2  20.1   7.9e-27     1e-23       1      72 [.      14      85 ..      14      91 .. 0.94

  Alignments for each domain:
  == domain 1  score: 83.2 bits;  conditional E-value: 7.9e-27
                .HHHHHHHHHHHHHHHHHHHTT-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
   GN3L_Grn1  1 rkrykiekkvkehnrKerKeakknptwkskkkkdpgIPnsfPfKeeiLeeieekkrkkeeekekkkeakkee 72
                r+r+kiek  ++++rK+rK+akk+ptw+sk kkdpgIPn+fPfK++iL+eieekkr+k+ee+++ +e+++e+
  EEA20549.1 14 RLRHKIEKAGAAKQRKARKQAKKDPTWRSKIKKDPGIPNLFPFKDKILAEIEEKKRQKQEEQLRIREEARER 85
                78*****************************************************************97665 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.0   4.3e-05     0.055      51     114 .]     180     250 ..     143     250 .. 0.71
   2 !   51.3   0.0   8.5e-17   1.1e-13       2      81 ..     320     402 ..     319     431 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 4.3e-05
                 EECGGCSS....HHHHHHHHHHHHHHHHC.TSEEEEEEETT....TTCSHHHHHHHHHHHHH.TTSEEEEEEES CS
    MMR_HSR1  51 vDtpGlie....gaseekglgkaflalee.adlillvvdas....eeklkpldeeleellee.akkplilvlnk 114
                  D+p + +    ++s+++ + k f+++ + ad+il+v+da+    +   k++++e+ +   e   k+lil+lnk
  EEA20549.1 180 GDIPTIASqvasKESSRRAFDKVFKQVAQaADVILYVLDARdpegT-RSKDVEREIMAA--EgGSKRLILILNK 250
                 5788853233334555668999999999967********9975431.233344444333..2367889999998 PP

  == domain 2  score: 51.3 bits;  conditional E-value: 8.5e-17
                 EEEEESTTSSHHHHHHHHHT......S.TEEESSSTTSSSSEEEEEEEETTEEEEEEECGGCS.SHHHHHHHHHHHHHHHHCTSEEEE CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltg......e.kaivsdkpgtTrdinegrvklkgkeielvDtpGli.egaseekglgkaflaleeadlill 81 
                 v+++G+pNvGKS++inalt       + ++ +++++g+T+  +e +++   ++++l+D pG++    +++k  +k+ ++++ea l+ll
  EEA20549.1 320 VGVIGYPNVGKSSVINALTArlnrgrSnACPTGAEAGVTTSLREVKLD---SKLKLIDSPGIVfP--NSHKASSKKKRENDEARLVLL 402
                 89*****************6444443236799*************997...79********7642..233344555555566655543 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.0   2.2e-09   2.8e-06      16     161 ..     210     378 ..     194     383 .. 0.78

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 2.2e-09
                  --EEEEEEESTTTT.--HHHHHHHHHHHHHTT-EEEEEEE-GGG--HHH.................HHHHHHHHHHHTTSEEEE--TTTHTTHHHHHH CS
  RsgA_GTPase  16 vdqllivvslkepe.lslnlldrfLvlaeekgiepvivlnKiDlleeee.................eleelkeelealgyevllvsaktkegleelke 95 
                   d +l v+ + +pe ++++ ++r +++ae    +++++lnKiDl+  +                  ++++ + + ++++ + l+v+ ++++ +++lk+
   EEA20549.1 210 ADVILYVLDARDPEgTRSKDVEREIMAAEGGSKRLILILNKIDLVPPAVlkgwlihlrryfptlplKASNGAPNAHSFDHKQLTVKGTSETLFKALKS 307
                  45566666666665367889***************************9999*************9988888999999999999999999999999987 PP

                  H.....CTTSEEE.EECSTTSSHHHHHHHHCTT---.--S--------------SEEEEEETTTEEEESS-SS CS
  RsgA_GTPase  96 l.....lkdktsv.lvGqSGvGKStLinallpelel.ktgevseklgrGkhTTtavellelaegglliDtPGf 161
                  +     lk  +sv ++G   vGKS++inal+ +l+  + ++  +  + G   Tt+ + ++l+++  liD+PG+
   EEA20549.1 308 YsqtsqLKRAISVgVIGYPNVGKSSVINALTARLNRgRSNACPTGAEAGV--TTSLREVKLDSKLKLIDSPGI 378
                  61111144444444778888************875415666666666664..5566667889999*******8 PP

>> FeoB_N  Ferrous iron transport protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0      0.25   3.2e+02      76     118 ..     207     254 ..     177     260 .. 0.71
   2 !   20.9   0.0   1.6e-07    0.0002       2      57 ..     319     378 ..     318     412 .. 0.76

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.25
                 CTSSSEEEEEEEGGGHH..HHHHHHHHHHHTT...SSEEEEEETHHHH CS
      FeoB_N  76 eeepdvvvnvvdatnle..rnLyLtlqllelg...vpvvlalnmidea 118
                  + +dv++ v+da   e  r+  +  +++  +   ++++l+ln+id +
  EEA20549.1 207 AQAADVILYVLDARDPEgtRSKDVEREIMAAEggsKRLILILNKIDLV 254
                 567899999999998764456666666665543346788888888865 PP

  == domain 2  score: 20.9 bits;  conditional E-value: 1.6e-07
                 EEEEEESTTSSHHHHHHHHHTTSEE.......EEESTTSSSEEEEEEEEETTEEEEEEE---- CS
      FeoB_N   2 tvalvGnpnvGkttlfnaltgakqk.......vgNwpGvtvekkegklklkgkeveivDlPGi 57 
                 +v ++G pnvGk++++nalt   ++        g  +Gvt   +e+kl+   ++++++D PGi
  EEA20549.1 319 SVGVIGYPNVGKSSVINALTARLNRgrsnacpTGAEAGVTTSLREVKLD---SKLKLIDSPGI 378
                 6889***************965332111222267778999999999988...99********8 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.9   1.1    0.0046       5.9     119     167 ..     193     250 ..      10     251 .. 0.84
   2 !   10.6   0.1   0.00033      0.43       1      21 [.     320     340 ..     320     359 .. 0.87
   3 ?    4.2   0.0     0.032        41      98     120 ..     365     386 ..     351     411 .. 0.72

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0046
                 S.......HHHHHHHSTTEEEEEEEETTS.-CCC-.CHHHHHHHHSTTBTTEEEEEE- CS
   Dynamin_N 119 q.......elvkeyikkadiilavtsanh.dlsns.ealflarevdpkgkrtivvltk 167
                 +       ++ k+ ++ ad+il+v++a   + ++s ++++   +++  +kr i +l+k
  EEA20549.1 193 EssrrafdKVFKQVAQAADVILYVLDARDpEGTRSkDVEREIMAAEGGSKRLILILNK 250
                 235556646666666************9943444446777777777777889999988 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00033
                 EEEEEBTTTTHHHHHHHHHTS CS
   Dynamin_N   1 iavvGsqSsGKSSvlnaLlge 21 
                 + v+G  + GKSSv+naL+ +
  EEA20549.1 320 VGVIGYPNVGKSSVINALTAR 340
                 689***************865 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.032
                 TTS-SEEEEE---B-SSSGTTSH CS
   Dynamin_N  98 llvkgltlvDlPGldsvnkrdqe 120
                  l+++l+l+D+PG+   n ++ +
  EEA20549.1 365 KLDSKLKLIDSPGIVFPNSHK-A 386
                 56789*********8766554.4 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   1.5       3.1     4e+03      30      58 ..      64      91 ..      57     110 .. 0.64
   2 !   10.0   0.0   0.00037      0.47      83     135 ..     199     254 ..     196     281 .. 0.76
   3 !    8.2   0.0    0.0013       1.7       2      79 ..     316     377 ..     315     380 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 3.1
                SCHHHHHHHHHSTHCHSHHHHHHTSCSSC CS
    GTP_EFTU 30 iskkgekaeeervlDtlkeErergiTiks 58
                i++ ++++++e++l  ++e rer+   k 
  EEA20549.1 64 IEE-KKRQKQEEQLRIREEARERCKAEKK 91
                333.2333445678899999999876554 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00037
                 GHHHHHHHHHT-SEEEEEEETT..TB.STHHHHHHHHHHHHTTTEEEEEEESCGST CS
    GTP_EFTU  83 FskevirglrvlDgavlvvdav..eG.vepqteevlrlalkegvpiivfiNKmDrl 135
                 F k   + ++++D+ + v+da+  eG      e+ +  a     ++i+++NK+D +
  EEA20549.1 199 FDKVFKQVAQAADVILYVLDARdpEGtRSKDVEREIMAAEGGSKRLILILNKIDLV 254
                 55666677899***********44453444555666666666667*********98 PP

  == domain 3  score: 8.2 bits;  conditional E-value: 0.0013
                 CEEEEEEEESTTSSHHHHHHHHHHHTTSSCHHHHHHHHHSTHCHSHHHHHHTSCSSCEEEEEETTCSSEEEEEEEESS CS
    GTP_EFTU   2 rirnigiighvDhGKtTLtdrLlyktgaiskkgekaeeervlDtlkeErergiTiksaaisleketkkylinliDtPG 79 
                 r + +g+ig  + GK++++ +L++++++ ++              ++  e g+T +   ++l+      +++liD+PG
  EEA20549.1 316 RAISVGVIGYPNVGKSSVINALTARLNRGRS-----------NACPTGAEAGVTTSLREVKLD-----SKLKLIDSPG 377
                 67899******************98887544...........357888999999999999999.....8899999999 PP

>> AIG1  AIG1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0     0.045        58      54      95 ..     180     221 ..     164     263 .. 0.81
   2 !   11.3   0.0   0.00013      0.16       5      86 ..     322     409 ..     318     445 .. 0.67

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.045
                 EE--SCCCTTCCHHCHHHHHHHHHHHCTT-ESEEEEEEETTB CS
        AIG1  54 iDTPglfdlsvsadkiskeivrclllseegihalllvlslgr 95 
                  D P + +  +s+++ ++   + ++  ++  +++l+vl++++
  EEA20549.1 180 GDIPTIASQVASKESSRRAFDKVFKQVAQAADVILYVLDARD 221
                 58999999999***************************9984 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00013
                 EESSTTSSHHHHHHHHHTS.--SS--TTTS---SS-EEEEE.EETTEEEEEEE--SC.CCTTC...CHHCHHHHHHHHHHHCTT-ESE CS
        AIG1   5 lvGktgnGkSaTgNsilgk.kaFesklsaqsvtkkcqkksr.twdgkkinViDTPgl.fdlsv...sadkiskeivrclllseegiha 86 
                 ++G   +GkS+ +N++  + +  +s+++ ++    ++++ r ++ + k++ iD Pg+ f  s+   s++k +++  r +ll++ ++  
  EEA20549.1 322 VIGYPNVGKSSVINALTARlNRGRSNACPTGAEAGVTTSLReVKLDSKLKLIDSPGIvFPNSHkasSKKKRENDEARLVLLNAVPPKQ 409
                 689999**********655266899999999999999998878889**********95444431223444445555566666655555 PP

>> MeaB  Methylmalonyl Co-A mutase-associated GTPase MeaB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.3         2   2.6e+03     194     209 ..      31      46 ..      15      92 .. 0.49
   2 ?   14.7   0.0   8.5e-06     0.011      25      55 ..     313     343 ..     293     349 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 2
                 HHCSTTBTTB--EEEE CS
        MeaB 194 eleeekekeWrpkvlk 209
                 +++ +k+ +Wr+k+ k
  EEA20549.1  31 RKQAKKDPTWRSKIKK 46 
                 3444444455554443 PP

  == domain 2  score: 14.7 bits;  conditional E-value: 8.5e-06
                 G-S-SEEEEEEE-TTSSHHHHHHHHHHHHHC CS
        MeaB  25 kaGraqvvGltGvPGaGkstlvealglelrr 55 
                 +  ra  vG+ G P +Gks +++al+++l r
  EEA20549.1 313 QLKRAISVGVIGYPNVGKSSVINALTARLNR 343
                 4569999********************9975 PP

>> Nuc_deoxyri_tr2  Nucleoside 2-deoxyribosyltransferase like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.6    0.0086        11      13      72 ..      35      87 ..      29      89 .. 0.88
   2 ?    6.0   0.0     0.011        14      65     103 ..     204     246 ..     179     251 .. 0.65

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0086
                     SSST-HHHHHHHHHHTSSS-EEEEE----SS-----HHHHH.....HHHHHHHHHHHH-S CS
  Nuc_deoxyri_tr2 13 eaetdWredlteaLsaipklgvtvfnPqredwdseleedrskkrfreqvewelealekAd 72
                     +++++Wr ++    +  ++ g+  + P ++++ +e+ e+++ ++++eq ++  ea e+++
       EEA20549.1 35 KKDPTWRSKI----K--KDPGIPNLFPFKDKILAEI-EEKKRQKQEEQLRIREEARERCK 87
                     78899*****....3..4899*************98.88888999***********9996 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.011
                      HHHHHH-SEEEEEE-TT--.-HHHH.HHHHHHTTS..S-EEEE CS
  Nuc_deoxyri_tr2  65 lealekAdvvvfvfdgeds.atrsl.vElglaaak..gkkvvl 103
                       +  ++Adv+++v+d +d  +trs  vE   +aa+  +k+++l
       EEA20549.1 204 KQVAQAADVILYVLDARDPeGTRSKdVEREIMAAEggSKRLIL 246
                      455678**********877678887855555544431555655 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.7       4.2   5.4e+03     103     124 ..      73     101 ..      70     121 .. 0.71
   2 ?   -1.0   0.4       1.9   2.5e+03      35      56 ..     152     170 ..     101     224 .. 0.57
   3 ?   14.1   0.0     4e-05     0.052       1      61 [.     320     402 ..     320     430 .. 0.69

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 4.2
      AAA_18 103 peelleRlekRgyeeakik.......ene 124
                 +e+l+ R e+R++ +a++k       ++e
  EEA20549.1  73 EEQLRIREEARERCKAEKKaagietaDDE 101
                 57788888888888877776666444333 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 1.9
      AAA_18  35 nglllevdpealdeskrldedk 56 
                 +++++++d++   +++r+d+d 
  EEA20549.1 152 DEMSEDYDDD---DEDRMDQDG 170
                 2222222222...344444433 PP

  == domain 3  score: 14.1 bits;  conditional E-value: 4e-05
      AAA_18   1 IlltGtpGvGKttlakeLskrlgf..............gvnlrdvakenglllevdpe........aldeskrldedkldkll 61 
                 +++ G+p vGK+++ ++L  rl+                + lr+v  ++ l l + p         a +++kr++++ + +ll
  EEA20549.1 320 VGVIGYPNVGKSSVINALTARLNRgrsnacptgaeagvTTSLREVKLDSKLKLIDSPGivfpnshkASSKKKRENDEARLVLL 402
                 6899**************99886677888899888888444444444444444444444222233355555555555555555 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.017        22      70     120 .]     200     253 ..     190     253 .. 0.72
   2 ?    5.1   0.0      0.02        25       3      22 ..     321     340 ..     319     374 .. 0.70

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.017
                 TTT-HHHHCTSCEEEEEEEGHHH..HCHHHHHHHHHHH.CSSS-EEEEEE-TTT CS
         Roc  70 rslhplylreaalailvydsrss..enlkeWlkelkkv.agkspvilvgnkiDl 120
                 +++ +   ++a+++++v+d+r+   ++ k+  +e+ +  +g++ +il+ nkiDl
  EEA20549.1 200 DKVFKQVAQAADVILYVLDARDPegTRSKDVEREIMAAeGGSKRLILILNKIDL 253
                 4555555678899999***88642256677777777651667899*******95 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.02
                 EEESSTTSSHHHHHHCHCT- CS
         Roc   3 vlvGdsgvGKtsllkrfved 22 
                  ++G  +vGK+s ++ ++ +
  EEA20549.1 321 GVIGYPNVGKSSVINALTAR 340
                 589************99864 PP

>> DUF2574  Protein of unknown function (DUF2574)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0   0.00053      0.68      42      93 .]     200     252 ..     178     252 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00053
     DUF2574  42 evvnaqlqqrcGnltyvadarelasspvrGvttevvtvpgdskrqi.vlnryd 93 
                 + v  q+ q      yv dar++  +  + v  e++++ g+skr i +ln+ d
  EEA20549.1 200 DKVFKQVAQAADVILYVLDARDPEGTRSKDVEREIMAAEGGSKRLIlILNKID 252
                 55677999999999******************************983567765 PP

>> NOG1  Nucleolar GTP-binding protein 1 (NOG1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.2      0.26   3.3e+02      29      46 ..      70      87 ..      63      92 .. 0.80
   2 ?    7.2   0.0    0.0033       4.2      12      58 .]     208     252 ..     205     252 .. 0.75

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.26
        NOG1 29 ysleeQlsLleeikelfa 46
                 + eeQl+++ee +e+ +
  EEA20549.1 70 QKQEEQLRIREEARERCK 87
                6679********999876 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0033
        NOG1  12 hladavlFllDpseecgysleeQlsLleeike.lfankpvivvlnKiD 58 
                 + ad++l++lD+    g+  ++   + +ei + + ++k++i +lnKiD
  EEA20549.1 208 QAADVILYVLDARDPEGTRSKD---VEREIMAaEGGSKRLILILNKID 252
                 6789*********999998886...55555540444588999999998 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00065      0.83      17      51 ..     310     344 ..     297     414 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00065
      AAA_16  17 ervrsgrpelvllsGesGvGKsslvrellralekd 51 
                 ++    r  +v ++G++ vGKss++++l  +l++ 
  EEA20549.1 310 QTSQLKRAISVGVIGYPNVGKSSVINALTARLNRG 344
                 4444444468889****************999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (549 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1190  (0.0663729); expected 358.6 (0.02)
Passed bias filter:                      518  (0.0288917); expected 358.6 (0.02)
Passed Vit filter:                        91  (0.00507558); expected 17.9 (0.001)
Passed Fwd filter:                        35  (0.00195214); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.90u 0.31s 00:00:01.21 Elapsed: 00:00:00.48
# Mc/sec: 3453.99
//
Query:       EEA20550.1  [L=286]
Description: CBF/NF-Y family transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      1e-06   28.9   0.0    2.2e-06   27.9   0.0    1.6  1  CBFD_NFYB_HMF   Histone-like transcription factor (CBF/NF-Y) 
     0.0017   18.7   0.1     0.0017   18.7   0.1    2.8  3  Histone         Core histone H2A/H2B/H3/H4
  ------ inclusion threshold ------
        2.9    7.8  24.8        4.3    7.2  24.8    1.3  1  TFIIA           Transcription factor IIA, alpha/beta subunit
        4.4    6.8  20.2       0.74    9.4  16.3    1.7  2  VIR_N           Virilizer, N-terminal
        6.7    6.6  21.5       0.74    9.7  16.9    1.6  2  SRP-alpha_N     Signal recognition particle, alpha subunit, N
        7.8    4.8  11.9         14    3.9  11.9    1.4  1  Adeno_terminal  Adenoviral DNA terminal protein


Domain annotation for each model (and alignments):
>> CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) and archaeal histone
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.9   0.0   7.2e-10   2.2e-06       3      65 .]      53     113 ..      51     113 .. 0.93

  Alignments for each domain:
  == domain 1  score: 27.9 bits;  conditional E-value: 7.2e-10
                    XXHHHHHHHHHCC.TTXS-B-HHHHHHHHHHHHHHHHHHHHHHHHHHCCTTSSCE-HHHHHHHH CS
  CBFD_NFYB_HMF   3 LPiarvkkImksd.pdarkiakdAkeliaecveefieelaseAaeickkekrKtikaehiklAv 65 
                    LP a  +++ ks  p +  i kdA   i+++++ fi++l+s A+e +    ++t+++ +++ A+
     EEA20550.1  53 LPRAVTQRLAKSVlPPDTAIQKDALLAIQKAATVFISYLSSHANEATL---KRTLAPSDVLNAL 113
                    99999*********99999**************************986...6899999998886 PP

>> Histone  Core histone H2A/H2B/H3/H4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.1   5.7e-07    0.0017      45     124 ..      36     109 ..       2     114 .. 0.75
   2 ?   -1.5   1.3         1   3.1e+03      49      49 ..     161     161 ..     125     217 .. 0.57
   3 ?   -2.9   5.6       2.8   8.4e+03      12      55 ..     202     246 ..     190     255 .. 0.50

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 5.7e-07
                 HHHHHHHHHHHHXXSXXSXHHHHHHHHHHHH.TTSSSXEEXHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTXSEEXHHHH CS
     Histone  45 tvalkeirkyqkstdlliqklpfaRvvreivksekedlrisaeavlalqealEallvelfeeAnllakhaKRvTitpkDi 124
                 ++  k + +  + +dll +++  +R+ + + +    d  i+++a+la+q+a+  ++  l ++An ++ +   +T+ p D+
  EEA20550.1  36 EQQAKAQSEGVSVEDLLLPRAVTQRLAKSVLP---PDTAIQKDALLAIQKAATVFISYLSSHANEATLK---RTLAPSDV 109
                 44445555566779*****************9...9****************************99874...57777776 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1
                 H CS
     Histone  49 k 49 
                  
  EEA20550.1 161 I 161
                 1 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 2.8
                 XXEEXXXXXXXXXXHT.TS-SSSSB--TTT-XTTHHHHHHHHHHH CS
     Histone  12 sektapekkvsakker.kasskskkkkkrryrpgtvalkeirkyq 55 
                  ek++p+++ + + e+  +++ + + ++  +    ++++e+++ q
  EEA20550.1 202 NEKHSPDETEVDEDETeEEEEAEPEEEEEEEDEEAEEEDEEEETQ 246
                 445555555555555544444444444444444444444444444 PP

>> TFIIA  Transcription factor IIA, alpha/beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2  24.8    0.0014       4.3     171     366 ..      27     249 ..       3     277 .. 0.28

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0014
       TFIIA 171 aqssvaalqaqsqqaqalaepqqqlekq.................qqqqqqqqqqqqqq.qvqqqqqe......................esqqaqqas 229
                 a+++++++++q  qa+a++        +                 +      ++++ +  ++q++                         +        
  EEA20550.1  27 AAAANSQMTEQ--QAKAQS--------EgvsvedlllpravtqrlA------KSVLPPDtAIQKDALLaiqkaatvfisylsshaneatlK-------- 101
                 11111111111..111111........0112222333322211110......112222212221111122222233333322111111110........ PP

       TFIIA 230 qe............qvagsqvessqtdgaedaleeespv..legelsaeeeagaqkeelsreeidri.reealkakelekeskkkkraeessla..... 308
                  +            +++ +++                    le el a+ +a a+k+++++++  +                           +     
  EEA20550.1 102 -RtlapsdvlnalsELEFDSL-----------------RpqLERELDAHTAALADKKKAQKDRKAATtTT-----------------------Tsgtqa 159
                 .11111111111111111111.................11112222222222221111111111111000.......................011112 PP

       TFIIA 309 ..............................dlseilqlDGagddsdeeeeeeesdedsdsessdd..edeqveEDplNSd.DDvddedddd 366
                                               + ++ ++ D ag ++ + +e +e ded+++e+++   e+e++eED   ++ D +++ +++d
  EEA20550.1 160 eikdgdeagavpaaggekkdvprssttsviKGNKRIKRDSAGNEKHSPDE-TEVDEDETEEEEEAepEEEEEEEDEEAEEeDEEEETQEAD 249
                 22222222333333333333333333344466666666766666665332.2233332222222213333322222222213332222222 PP

>> VIR_N  Virilizer, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.1      0.79   2.4e+03     181     206 ..      11      33 ..       4      52 .. 0.41
   2 ?    9.4  16.3   0.00025      0.74     172     260 ..     156     249 ..     106     250 .. 0.69

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.79
       VIR_N 181 pPpdddeeedaavpetveeekeense 206
                 pP d+d+ +  +++++       ns+
  EEA20550.1  11 PPTDNDDIS-SPTTAAAA--AAANSQ 33 
                 444433333.22222222..122221 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.00025
       VIR_N 172 aytgnv.....astpPpdddeeedaavpetveeekeensekredy.leeesPeertslkaeekdseaereeresseeierdeeesdvrerekese 260
                   ++++     a+  P    e++d++ ++t++  k ++++kr+    e++sP ++t++ ++e++ e+e e +e++ee +++ ee+d +e+ +e +
  EEA20550.1 156 GTQAEIkdgdeAGAVPAAGGEKKDVPRSSTTSVIKGNKRIKRDSAgNEKHSP-DETEVDEDETEEEEEAEPEEEEEEEDEEAEEEDEEEETQEAD 249
                 3333334444488888888888899999999988888888776652678888.888999999998877777766666666666666666666655 PP

>> SRP-alpha_N  Signal recognition particle, alpha subunit, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.1      0.67     2e+03     267     276 ..      29      38 ..       4      55 .. 0.44
   2 ?    9.7  16.9   0.00025      0.74      89     253 ..     116     268 ..      82     282 .. 0.43

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.67
                  XXXXXXXXXX CS
  SRP-alpha_N 267 vdastwgskt 276
                  +++s++ ++ 
   EEA20550.1  29 AANSQMTEQQ 38 
                  1111111111 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.00025
                  ..HHHHHHHHHHHHXXXXXXXXX........XXX..XXXXXXXXXX.....XX.XX................XX..XXXXX...XXXXXXXXXX.XXX CS
  SRP-alpha_N  89 y.FdeyFdqllrelEasaeaakkskaakepkamksfeeskkskktvksskedkkpe.....gkkkkgakkekda..sddstpsatpetsrpstp.sgl 177
                    Fd    ql rel+a ++a + +k+a+++++  + ++++ s ++ + +  d++++     g       ++kd   s  st s  + ++r +    g+
   EEA20550.1 116 LeFDSLRPQLERELDAHTAALADKKKAQKDRK--AATTTTTSGTQAEIKDGDEAGAvpaagG-------EKKDVprS--STTSVIKGNKRIKRDsAGN 202
                  35777777889999999988877766654444..3333334444333233333232223321.......22222111..1111111111111111112 PP

                  XXXX..XXX.XXXXXXXXXXXXXX..XXXXXXXXXXX....XXXXXXX..XXXXXX.XXXXXXXXXXXXXXXXXXXXX CS
  SRP-alpha_N 178 ltake.agptaedvsrrarkkankkrssagassgdeakasksskkkkkkpkkkgkk.aRvWdadgsadeedkLDySap 253
                  ++++  + +++ed  + + ++  +    ++ +++de+   ++++ +++ + +++    Rv d dg++      Dy ++
   EEA20550.1 203 EKHSPdETEVDEDETEEEEEAEPE----EEEEEEDEE---AEEEDEEE-ETQEADNlDRVEDLDGKMH----ADYDDD 268
                  222210112122222222222221....112222222...22222333.3344455599999997533....344433 PP

>> Adeno_terminal  Adenoviral DNA terminal protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9  11.9    0.0048        14     166     349 ..      69     251 ..      20     265 .. 0.50

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.0048
  Adeno_terminal 166 rqasekDaallkeirklkvalcnylilyakdsaqteedrrflpgadvlslPcdedW..leafvekfseleipe...aenkirlkstdassvksLg 255
                      +a +kDa l  +i+k  + ++ yl    ++ ++    +r l ++dvl+   + ++  l   +e+  el+++    a++k   k     + k+ +
      EEA20550.1  69 DTAIQKDALL--AIQKAATVFISYLS---SHANE-ATLKRTLAPSDVLNALSELEFdsLRPQLER--ELDAHTaalADKKKAQK-----DRKAAT 150
                     3445555533..56666666666665...44444.256899******987644433114444443..44444411333333333.....333333 PP

  Adeno_terminal 256 ggglhGgaltlrsgdrtGlp......feLRpRengRaiteemRR.sRgel..vrrfvDrLPvrRRrRreesPlppPeeeeeGiaaeeeeeeeeee 341
                      ++ +G+  +++ gd +G +       +  pR    ++ +  +R +R ++   +   D   v   + +ee+ +  Peeeee + +ee eee+eee
      EEA20550.1 151 TTTTSGTQAEIKDGDEAGAVpaaggeKKDVPRSSTTSVIKGNKRiKRDSAgnEKHSPDETEVDEDETEEEEEAE-PEEEEE-EEDEEAEEEDEEE 243
                     33444555555555555543111111344677766666644444034333113556788888888887777776.676666.4566666666666 PP

  Adeno_terminal 342 eeledevi 349
                     e+ e + +
      EEA20550.1 244 ETQEADNL 251
                     66555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (286 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2021  (0.112722); expected 358.6 (0.02)
Passed bias filter:                      726  (0.0404931); expected 358.6 (0.02)
Passed Vit filter:                       215  (0.0119917); expected 17.9 (0.001)
Passed Fwd filter:                        92  (0.00513135); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.21u 0.37s 00:00:01.58 Elapsed: 00:00:00.49
# Mc/sec: 1740.60
//
Query:       EEA20551.1  [L=567]
Description: SIR2 family histone deacetylase (Hst4), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.4e-30  104.4   0.0      3e-29  102.2   0.0    1.9  1  SIR2      Sir2 family
  ------ inclusion threshold ------
      0.018   15.4   0.0      0.037   14.4   0.0    1.5  1  ACP_PD    Acyl carrier protein phosphodiesterase


Domain annotation for each model (and alignments):
>> SIR2  Sir2 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.2   0.0   3.3e-33     3e-29       1     175 [.     123     336 ..     123     338 .. 0.79

  Alignments for each domain:
  == domain 1  score: 102.2 bits;  conditional E-value: 3.3e-33
                 -GGGGGGGT---SSSTTSHHHHSCHHH.HSSHHHH.HHHHHHHHH....HHHHHHHHHHCC..TSS--HHHHHHHHHHHTTCEEEEEES-SSSHHHHTT CS
        SIR2   1 GAGiStesGipdfRskeGlyaklakee.laspeal.fskkllvee....vfyniarellae..eaepnaaHkalkklekkgkllrliTQNiDgLekkaG 91 
                 GAGiSt++GipdfRs++Gl++ ++k++ l+s  +l f+  + +++     f +++r+l +e  +++p+a H++l+ + k ++l+rl+TQNiD +e +  
  EEA20551.1 123 GAGISTSAGIPDFRSSDGLFKSVQKKHnLKSSGKLlFDAAVYRDDsltaSFHEMVRTLSKEaaDTKPTAFHHMLARMAKDNRLSRLYTQNIDCIETSLQ 221
                 9********************99877657776554155555555577777999999998877899***************************9886422 PP

                 -S.............SEEETTEEEEEEEETTTSBEEECCGGHCHHHCCTT.B-TTTCC................BEEEEE--CTSB-S..HHHHHHHH. CS
        SIR2  92 sk.............kvvelHGslakakcvkcekkldkeelqeeieaekvpecekcgk................llkpdvvfFGealp..dklkklie. 158
                                + ++lHGsl k+ c kc++  + +   +  +  + p c+ c++                 ++p++v++ e+ p  +++  +++ 
  EEA20551.1 222 PLitqvplppkapwpTCIQLHGSLDKMVCQKCRHLAEFDP--NLFDGPEAPACPACTEtdelrtttgqrshgvgKMRPRIVLYNEHNPdeEAIAAVMNs 318
                 11112233344444499****************9777653..3444555577777777777************************99986677888888 PP

                 HHH.H-SEEEEES--STS CS
        SIR2 159 kve.eadlllviGtSlkV 175
                 +++ + d+++v+GtSlk+
  EEA20551.1 319 DIRsRPDTVIVVGTSLKI 336
                 765268**********97 PP

>> ACP_PD  Acyl carrier protein phosphodiesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   4.1e-06     0.037      11      68 ..     163     223 ..     157     249 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 4.1e-06
      ACP_PD  11 eysaepLeefvqrvyaql.ekneealPerlqrllprmieedwLesY..aelegieralqrm 68 
                  y + +L++ ++++ ++l ++  ++ P+ ++++l+rm++++ L++   ++++ ie++lq +
  EEA20551.1 163 VYRDDSLTASFHEMVRTLsKEAADTKPTAFHHMLARMAKDNRLSRLytQNIDCIETSLQPL 223
                 68889998877888888846667888*****************996346789999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (567 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       764  (0.0426125); expected 358.6 (0.02)
Passed bias filter:                      480  (0.0267723); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.33s 00:00:00.94 Elapsed: 00:00:00.48
# Mc/sec: 3573.49
//
Query:       EEA20552.1  [L=938]
Description: RNA polymerase II Mediator complex subunit Sin4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
   6.6e-180  599.7   0.0   7.6e-180  599.5   0.0    1.0  1  Med16        Mediator complex subunit 16
  ------ inclusion threshold ------
      0.042   14.1   0.0       0.68   10.3   0.0    2.8  3  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain


Domain annotation for each model (and alignments):
>> Med16  Mediator complex subunit 16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  599.5   0.0  8.5e-184  7.6e-180       2     757 ..     141     918 ..     140     919 .. 0.96

  Alignments for each domain:
  == domain 1  score: 599.5 bits;  conditional E-value: 8.5e-184
       Med16   2 dkatpkepgasIvafkWLniekpqivnkaaakdqerniykysvnqfrPigvfHPistkealvalrrsGqlkLlyqgenkveykkisvqlknvsesksre 100
                  + +p ++ga++v+++W+n+++ ++++++aak+++r  ++ys+++++Pig+fHP+ +k al++ +r+G ++Llyq ++++++ ++s++lk++   +s++
  EEA20552.1 141 TVVDPPDDGAQVVGMMWMNSNRAVHAFHQAAKVNGR--WNYSPYRRKPIGPFHPA-GKPALICFTRNGIMRLLYQ-NPDQRWVEVSAELKTTN--QSDR 233
                 578999******************************..*****************.*******************.****************9..88** PP

       Med16 101 lltkAaiaftndgqilvtayssltnkiqfYkvevnwkrqkldpeqktpk.eseklPsltlkhihqktedqcdeeg.................kvleLth 181
                 +lt+Aa  ++++g ilv+++s l++++++Y+v+++w+++++d++q++++ + +++P++++++i +kte++  ++                   +++Lt+
  EEA20552.1 234 ILTHAACLPSPNG-ILVATHS-LSERLSLYRVQIMWNPPQWDQAQQRQAsGVTPFPVPSIRIINCKTETPGRVFSfnkdqtddlqniapnqsFLYQLTN 330
                 *************.*******.7*********************9988625789**************9965555889999**********99****** PP

       Med16 182 ldiisatpekksg....psIlivysipgqs...........sSiieryqltkeanllhkafselgskksvtqkkskstlrlvddltldskiisitstel 265
                 l+ +s + ++  +    p+Il+vys+p +s           +S+ +r+ql+++   lh+ f+e+ skk++ q+++k ++r+++d+ +d+ + si+++e 
  EEA20552.1 331 LELVSGQFDNTGAttspPCILAVYSSPYNSaahdpqqqeppASVMVRWQLETSTLNLHPIFEESLSKKTNGQQRTKLEIRRMEDIHFDKHVVSIDQIEF 429
                 *****999977668899**********999********************************************************************* PP

       Med16 266 dlvvaiyydDgsievvdrnslkvvnetisgdyppktitslfdaGfkfpkisnknvlvlavSpsmtsivyldieGqlklkqleklkflgvsskel..sit 362
                 + v+ai+ dD+s++++d++s+++    ++++++ + +ts+++aGf fp++   ++l + +Sp+++ +v+ld++ q +l+  ++     +  ++   si 
  EEA20552.1 430 GCVLAITHDDSSVSFFDPKSMSQ----FTEGGDINAVTSIAQAGFRFPSD--TPGLNICFSPNSCLAVVLDTDWQAQLRISDYNFEPEGDLHDGknSIG 522
                 ***********************....9**********************..****************************9999777666666699*** PP

       Med16 363 saalaleyaiatgsdtssdDilllikteilrveklsekrtrnFiesviselhvsinftldaekesldkLlsspalqklLllqlelGpaqk..nnevvsd 459
                 ++alal +++++  +++ dD++++i       + ls ++++ F+++v+++l+ ++nf++++     dk +++p+++++L+lq++lG+ +   ++ + s+
  EEA20552.1 523 IVALALTFSRGCAIEYNTDDLIMTI------SRHLSTDAQNVFVNEVYRALPINCNFSMEQ-----DKPMQHPYVPRCLSLQAALGFQNFqtPRGLPSS 610
                 ************************9......88999************************9.....********************976588******* PP

       Med16 460 iawiiLnLrsasfalefvlrsikrqiskpsitrgeliqslignikWlidlvlyllqeLlqlayaknd.......vnsklklsnslvliillskvprlfl 551
                 + w++L Lr+as+++ f++++ k+  ++    + +++q++ gn+kW +d+ +yll++L+ la+++++       + +k+k+++sl+l ++l++++r+fl
  EEA20552.1 611 VPWAVLHLRHASLLFAFFFQYSKQPKEN-ETLDHDVLQMVYGNTKWALDFTQYLLNDLFSLAKEFEPilddqeaLAQKVKTTSSLSLTLVLASMSRAFL 708
                 ********************99999888.889******************************************************************* PP

       Med16 552 lkiisalgrihellkklhkdlakllgeskeslnrvfsilnnspvtldlfekfLreldalvtkeneeaglsdier...EkelLvkgeippeleelakvll 647
                   +++ l+++h +         +  g+ + + ++++  ++++pv+++++ekfL+ +++++++++++ag++d er   Ek +Lv+++ip ++ ++   l+
  EEA20552.1 709 HLVCRGLRGVHTSSIAS-----PFAGDGRAYSKELYALIDSAPVRFNVYEKFLNSVESAIKNAYQRAGFGDDERrtpEKDILVNSRIPAVMIPVIVSLF 802
                 ************99888.....9*******************************************************************99999**** PP

       Med16 648 drtsisllsevklsalyfydtswLgigedkrfenyvrtllvdii.......kktaddsivdslrkeqlakkkkqlRrCtRCgavslvgdplvrkatavk 739
                 ++t+++++ ev+++ +y++d+swLg+++d+r+e y++t++vdi+        + ++++i  ++++   +++  ++RrC+RC++++ + +  +r+   ++
  EEA20552.1 803 KQTIPAIRTEVDRMSIYLTDYSWLGFCHDRRTEHYRQTRQVDIVkkvplrgFDLSNGIIEPNVTSNGNKAGSSSRRRCVRCCEITGDPSS-PRSMLYFQ 900
                 ************************************************999788888888888888888888888**************5.******** PP

       Med16 740 alwtmvflrtCiCggawv 757
                       ++r+C+Cgg+w+
  EEA20552.1 901 LTLRLQLIRNCLCGGMWT 918
                 *****************7 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   7.6e-05      0.68      36      67 ..      97     128 ..      73     160 .. 0.86
   2 ?   -2.3   0.0      0.63   5.6e+03      31      57 ..     144     168 ..     134     174 .. 0.71
   3 ?   -0.2   0.0      0.14   1.2e+03      38      68 ..     418     448 ..     393     455 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 7.6e-05
  ANAPC4_WD40  36 kedsevrsLaWkpdgklLavaysdgevrllda 67 
                  + +++  +L+W++ g+ Lav  + g++++l++
   EEA20552.1  97 HLGQQLLHLCWNETGSDLAVLDASGRISILSI 128
                  56788899*********************997 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 0.63
  ANAPC4_WD40  31 tleedkedsevrsLaWkpdgklLavay 57 
                  +   ++++ +v +++W ++++     +
   EEA20552.1 144 D--PPDDGAQVVGMMWMNSNRAVHAFH 168
                  3..478899999999999888766555 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 0.14
  ANAPC4_WD40  38 dsevrsLaWkpdgklLavaysdgevrlldae 68 
                  d++v s+   + g +La+ ++d++v+++d +
   EEA20552.1 418 DKHVVSIDQIEFGCVLAITHDDSSVSFFDPK 448
                  56666666677799***********999865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (938 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       390  (0.0217525); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.68u 0.32s 00:00:01.00 Elapsed: 00:00:00.47
# Mc/sec: 6020.14
//
Query:       EEA20553.1  [L=125]
Description: 60S ribosomal protein L35 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.9e-18   64.6   0.7    5.9e-18   64.6   0.7    2.1  2  Ribosomal_L29  Ribosomal L29 protein
  ------ inclusion threshold ------
      0.059   12.7   2.4      0.077   12.3   2.4    1.2  1  CorA           CorA-like Mg2+ transporter protein
       0.46   10.7   5.9       0.21   11.8   3.0    1.7  2  Cortex-I_coil  Cortexillin I, coiled coil


Domain annotation for each model (and alignments):
>> Ribosomal_L29  Ribosomal L29 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.6   0.7   9.8e-22   5.9e-18       2      55 ..      10      64 ..       9      66 .. 0.96
   2 ?    1.3   0.3     0.057   3.4e+02       2      30 ..      84     112 ..      84     118 .. 0.85

  Alignments for each domain:
  == domain 1  score: 64.6 bits;  conditional E-value: 9.8e-22
                   HHHHS-HHHHHHHHHHHHHHHHHHHHHHHHT.SSS-CHHHHHHHHHHHHHHHHHH CS
  Ribosomal_L29  2 elrelsdeeLkeklkelkkeLfnLrfqkatg.qlenpsrirkvRkdIARikTvlr 55
                   +l ++s+++L ++l+elk+eL +Lr+qk ++ + +++ ri  +Rk+IARi+Tv++
     EEA20553.1 10 QLWGKSKDDLTKQLDELKTELGQLRVQKISQgASSKLNRIHDLRKSIARILTVIK 64
                   6899*************************998999******************97 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.057
                    HHHHS-HHHHHHHHHHHHHHHHHHHHHHH CS
  Ribosomal_L29   2 elrelsdeeLkeklkelkkeLfnLrfqka 30 
                    +lr++ +  ++ +l + ++ L + +  k+
     EEA20553.1  84 DLRSKQTRAIRRRLTKNEASLITEKQRKK 112
                    79999999999999999999998887775 PP

>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   2.4   1.3e-05     0.077     121     203 ..      17      99 ..       6     115 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.3e-05
        CorA 121 drlfellekleeeldeledeledstkkeilrelaqlrrrlvklrralapnrevlkrllakaddkllddedkeylrdlldeler 203
                 d+l ++l++l++el +l  +  ++   + l+++ +lr++++++ +++++n+++  rl  k+ + l  d ++++ r ++ +l++
  EEA20553.1  17 DDLTKQLDELKTELGQLRVQKISQGASSKLNRIHDLRKSIARILTVIKANQRAQLRLFYKGKKYLPLDLRSKQTRAIRRRLTK 99 
                 7788899999999999999999********************************99988555544444444456666555555 PP

>> Cortex-I_coil  Cortexillin I, coiled coil
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   3.0   3.5e-05      0.21      31      84 ..      15      73 ..      10      81 .. 0.82
   2 ?   -1.0   0.0      0.35   2.1e+03      16      31 ..      95     110 ..      83     119 .. 0.63

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3.5e-05
                   HHHHHHHHHHHHHHHHHHHH.....HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Cortex-I_coil 31 sreelikqkdelesllasle.....seaaerekrlreleakldealknleleklarlel 84
                   s+++l kq del+  l  l+     + a  + +r+++l+  +  +l  ++ ++ a+l l
     EEA20553.1 15 SKDDLTKQLDELKTELGQLRvqkisQGASSKLNRIHDLRKSIARILTVIKANQRAQLRL 73
                   99***********99987762222144567789*****************999999877 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.35
                    HHHHHHHHHHHHHHHH CS
  Cortex-I_coil  16 nklaglenslesekvs 31 
                     +l+  e sl +ek  
     EEA20553.1  95 RRLTKNEASLITEKQR 110
                    4566666666666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (125 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1339  (0.0746835); expected 358.6 (0.02)
Passed bias filter:                      614  (0.0342462); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.42u 0.24s 00:00:00.65 Elapsed: 00:00:00.40
# Mc/sec: 938.58
//
Query:       EEA20554.1  [L=227]
Description: vesicle transport v-SNARE protein Gos1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.8e-14   53.1   0.1    2.8e-14   53.1   0.1    2.8  3  V-SNARE_C        Snare region anchored in the vesicle membran
     0.0028   16.4   7.7     0.0041   15.9   7.7    1.1  1  GOLGA2L5         Putative golgin subfamily A member 2-like pr
  ------ inclusion threshold ------
       0.05   12.3   7.1      0.079   11.6   7.1    1.3  1  Dor1             Dor1-like family
      0.092   12.6   3.9       0.62    9.9   3.9    2.2  2  STAT_alpha       STAT protein, all-alpha domain
       0.15   11.5   3.1       0.24   10.8   1.4    1.7  2  Not3             Not1 N-terminal domain, CCR4-Not complex com
       0.34   11.5   5.9          1   10.0   5.1    2.2  2  Syntaxin-6_N     Syntaxin 6, N-terminal
       0.63    9.9   5.5        1.6    8.6   3.0    2.3  2  Sec34            Sec34-like family
       0.92   10.0   9.1       0.36   11.3   6.0    1.9  2  Snapin_Pallidin  Snapin/Pallidin
        2.5    6.6   4.0        3.4    6.2   1.4    1.7  2  FapA             Flagellar Assembly Protein A
        4.4    7.8   7.9          4    7.9   6.2    1.7  1  CENP-H           Centromere protein H (CENP-H)
        5.4    5.4   6.6        8.4    4.8   6.6    1.3  1  FUSC             Fusaric acid resistance protein family
        5.7    7.5  11.2        9.9    6.7   9.7    2.0  2  APG6_N           Apg6 coiled-coil region


Domain annotation for each model (and alignments):
>> V-SNARE_C  Snare region anchored in the vesicle membrane C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.1       2.4   3.6e+03      32      52 ..      58      78 ..      51      82 .. 0.63
   2 ?    1.5   0.6      0.25   3.8e+02      30      55 ..      87     112 ..      85     115 .. 0.83
   3 !   53.1   0.1   1.9e-17   2.8e-14       1      63 [.     140     202 ..     140     207 .. 0.94

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 2.4
   V-SNARE_C 32 hsQretLkrarsklhnvanrl 52
                 + re+L +  ++l++  ++l
  EEA20554.1 58 LEKRESLIGQLTRLLDSEATL 78
                455666666666666666665 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.25
   V-SNARE_C  30 dLhsQretLkrarsklhnvanrlgks 55 
                 +L++ re+L+  r+ l+ +++++  +
  EEA20554.1  87 NLARHREVLSEHRRELNRLSSSISEA 112
                 88999999999999999999988765 PP

  == domain 3  score: 53.1 bits;  conditional E-value: 1.9e-17
   V-SNARE_C   1 erllresdrlknShrivdetisiGaailedLhsQretLkrarsklhnvanrlgksnsiLrsik 63 
                 e+ l e+ r++nSh+++d+++s+++a+ e+++ QretL ++++++ ++a +++ +ns++ +i 
  EEA20554.1 140 EYMLEERGRIDNSHNMMDRVLSQAYAVNESFGLQRETLASINRRIVGAAGQIPGVNSLIGKIG 202
                 678899******************************************************995 PP

>> GOLGA2L5  Putative golgin subfamily A member 2-like protein 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   7.7   2.7e-06    0.0041      50     154 ..      14     125 ..      10     131 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 2.7e-06
                 XXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..XX....XXXXXXXXXXXX...X CS
    GOLGA2L5  50 sqvqeLeaslaeLknqaavkpaeeeaqppagPseeeqrlqeeleqLqkekealagqlqaqvrDneqLsrlnqeqe..er....Llelereaerws...e 139
                 +q + Le++   L ++  + ++ +  q p  Pseeeqr+++++++L +++e+l gql   +    +L+  + +q+  +r    L e  re++r s   +
  EEA20554.1  14 QQARSLETQTEALFHTYSQYASMS--QLPPKPSEEEQRIESQIQSLLEKRESLIGQLTRLLDSEATLTSSALKQNnlARhrevLSEHRRELNRLSssiS 110
                 567788888888877765444444..67999**************************999988888876555554123322236666777766552225 PP

                 XXXXXXXXXXXXXXX CS
    GOLGA2L5 140 eaedrkriLedmqsD 154
                 ea dr ++L +++sD
  EEA20554.1 111 EARDRANLLSNVRSD 125
                 889999999999998 PP

>> Dor1  Dor1-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   7.1   5.3e-05     0.079       7     103 ..      31     126 ..      10     128 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 5.3e-05
        Dor1   7 kpleelekepelLaeeaeeilaqiqdLarknyktlidaaealeairqelediraqledLvlklpkLteectrfskkaeeisekrkenkllldkheql 103
                 ++++++ + p +  ee ++i  qiq L  k +  li + + l +   +l +++ + ++L+ + + L+e  ++ +  +++ise r+ ++ll+++ +++
  EEA20554.1  31 SQYASMSQLPPKPSEEEQRIESQIQSLLEK-RESLIGQLTRLLDSEATLTSSALKQNNLARHREVLSEHRRELNRLSSSISEARDRANLLSNVRSDI 126
                 567888888888899***********9865.889999999999999999999**************************************9998876 PP

>> STAT_alpha  STAT protein, all-alpha domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   3.9   0.00041      0.62      18      95 ..      12      84 ..       9     116 .. 0.88
   2 ?   -2.1   0.0       2.1   3.1e+03      12      42 ..     150     180 ..     141     189 .. 0.74

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00041
  STAT_alpha 18 teqdirkLedeqeeFdfqyqelqkleqeraesekkelkkqkellqqmlnaLdqkRkelvdklkellnlleslqeklld 95
                + q+ r+Le + e +   y+++ ++     ++  ++ +++++ +++++++L +kR++l+ +l +ll+   +l ++ l+
  EEA20554.1 12 LRQQARSLETQTEALFHTYSQYASM-----SQLPPKPSEEEQRIESQIQSLLEKRESLIGQLTRLLDSEATLTSSALK 84
                6789999**9***999999999999.....555666789999************************999999888775 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 2.1
  STAT_alpha  12 rskvqeteqdirkLedeqeeFdfqyqelqkl 42 
                  ++ +++++ +++   + e+F +q ++l ++
  EEA20554.1 150 DNSHNMMDRVLSQAYAVNESFGLQRETLASI 180
                 5566667777777777888888888888777 PP

>> Not3  Not1 N-terminal domain, CCR4-Not complex component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.2    0.0049       7.3     128     187 ..      12      73 ..       9      80 .. 0.77
   2 ?   10.8   1.4   0.00016      0.24     119     215 ..      41     135 ..      29     147 .. 0.78

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0049
        Not3 128 lkdaideLneqvekleaeieklsskkkkkkk.skeka.rveeleklierhkfhieklelllr 187
                 l+++ ++L++q+e+l + + + +s ++   k s+e++   +++++l+e+++  i +l+ ll+
  EEA20554.1  12 LRQQARSLETQTEALFHTYSQYASMSQLPPKpSEEEQrIESQIQSLLEKRESLIGQLTRLLD 73 
                 55677888999999988888888877665565777774556899999999999999988775 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00016
        Not3 119 kekeearewlkdaideLneqvekleaeieklsskkkkkkkskekarveeleklierhkfhieklelllrlleneelepeevekikedieyyvesnqd 215
                  + +e ++ ++++i++L e+ e+l  ++ +l  ++ +    ++  + ++l ++ e  + h ++l+ l   +++ + +++ + +++ di+ y +sn  
  EEA20554.1  41 PKPSEEEQRIESQIQSLLEKRESLIGQLTRLLDSEATLT--SSALKQNNLARHREVLSEHRRELNRLSSSISEARDRANLLSNVRSDIDAYRSSNPH 135
                 455666777888888888888888888877766554443..333499999999999999********************************999755 PP

>> Syntaxin-6_N  Syntaxin 6, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   5.1   0.00067         1      16      97 ..      22     104 ..       9     128 .. 0.70
   2 ?    8.6   4.0    0.0018       2.6       7      55 ..      51     111 ..      47     190 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00067
  Syntaxin-6_N  16 kaeslyrrw...erlledtssstseeldetrteLrkalrsiewdledLeetvriveknpskfkidekelsrrrafveevreevke 97 
                   ++e+l++++    ++ ++++++ see ++ ++++++ l++ e  + +L +     e+  +   ++++ l+r+r++++e r+e+++
    EEA20554.1  22 QTEALFHTYsqyASMSQLPPKP-SEEEQRIESQIQSLLEKRESLIGQLTRLL-DSEATLTSSALKQNNLARHREVLSEHRRELNR 104
                   4444444441114555555554.67777777777777777777777777777.44566677888888999999998888888775 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.0018
  Syntaxin-6_N   7 keeVqkslnkaeslyrrwerlledtss.s...........tseeldetrteLrkalrsiew 55 
                   ++++q+ l+k esl+++ +rll+++ + +            +e l+e+r+eL++  +si++
    EEA20554.1  51 ESQIQSLLEKRESLIGQLTRLLDSEATlTssalkqnnlarHREVLSEHRRELNRLSSSISE 111
                   6899********************9996435555555555555555555555554444443 PP

>> Sec34  Sec34-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0      0.23   3.5e+02      34      59 ..      10      35 ..       4      39 .. 0.71
   2 ?    8.6   3.0     0.001       1.6       8      87 ..      50     132 ..      44     163 .. 0.69

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.23
       Sec34 34 ksvsektsslheaceqlleeqkrlee 59
                 +  ++ +sl++++e l++  +++ +
  EEA20554.1 10 AQLRQQARSLETQTEALFHTYSQYAS 35
                55667778888888888777777665 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.001
       Sec34   8 keeecdelleqtdealeqLeeleek...fksvsektsslheaceqlleeqkrleelaeeieekLkyFeeldpitrkLnspgss 87 
                  e+++++lle+ +++  qL+ l ++    +s + k ++l ++ e l e++++l++l+ +i+e  +  + l ++ + +++  ss
  EEA20554.1  50 IESQIQSLLEKRESLIGQLTRLLDSeatLTSSALKQNNLARHREVLSEHRRELNRLSSSISEARDRANLLSNVRSDIDAYRSS 132
                 46788889999998888888886651114556668899999999999999999999999988766666666666666555555 PP

>> Snapin_Pallidin  Snapin/Pallidin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       4.7     7e+03      34      44 ..      14      24 ..      10      41 .. 0.42
   2 ?   11.3   6.0   0.00024      0.36      17      89 ..      49     119 ..      46     120 .. 0.87

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 4.7
  Snapin_Pallidin 34 eqldrlnekLk 44
                     +q ++l ++ +
       EEA20554.1 14 QQARSLETQTE 24
                     33333333322 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00024
  Snapin_Pallidin  17 eldeklkelrqsQeeLleqldrlnekLkeleeaqeaevlpdlkeyakKLvnikkrmsslnerlqklkkRaekL 89 
                      ++++++++l ++ e L  ql+rl ++ + l   +     ++l ++++ L++ ++++++l+++++++++Ra+ L
       EEA20554.1  49 RIESQIQSLLEKRESLIGQLTRLLDSEATLTSSAL--KQNNLARHREVLSEHRRELNRLSSSISEARDRANLL 119
                      7899******************9776665555555..469******************************865 PP

>> FapA  Flagellar Assembly Protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   1.4    0.0023       3.4     341     411 ..      11      85 ..       6      96 .. 0.71
   2 ?    2.1   0.2     0.038        57     337     368 ..      90     124 ..      72     208 .. 0.57

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0023
        FapA 341 eleeeleeleeeleklkkk......ikklpklkaekqlesekkeqlkklletkeklkeeleeleeelkelkeelesk 411
                 +l+++ ++le ++e l  +      +++lp+  ++++ e+++++q+++lle++e+l  +l+ l +  ++l ++  ++
  EEA20554.1  11 QLRQQARSLETQTEALFHTysqyasMSQLPP--KPSEEEQRIESQIQSLLEKRESLIGQLTRLLDSEATLTSSALKQ 85 
                 5666666666666666666555466666666..46667889999999999999999999999999888887776665 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.038
        FapA 337 ekl...keleeeleeleeeleklkkkikklpklka 368
                 + +   +e ++el++l +++ + +++ ++l++ + 
  EEA20554.1  90 RHRevlSEHRRELNRLSSSISEARDRANLLSNVRS 124
                 22222366666666666666666666555544222 PP

>> CENP-H  Centromere protein H (CENP-H)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   6.2    0.0027         4      13      92 ..      45     126 ..      41     126 .. 0.91

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0027
      CENP-H  13 sellklsqelrelqeeltevekenlrlkrknrelaaellelakekesek..eklkeelekleaelkksrqrwrvvknvasai 92 
                 +e +++++++++l+e+ +++  +  rl   +++l+++ l++++ +++++  +++++el++l + + ++r+r+ ++ nv s i
  EEA20554.1  45 EEEQRIESQIQSLLEKRESLIGQLTRLLDSEATLTSSALKQNNLARHREvlSEHRRELNRLSSSISEARDRANLLSNVRSDI 126
                 556788999*****************************888888888888*99************************98875 PP

>> FUSC  Fusaric acid resistance protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   6.6    0.0057       8.4     213     319 ..      11     134 ..       4     178 .. 0.69

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0057
        FUSC 213 rirararalrrllsrmlallallsslarllarlraeeaaavpelaallaelaal...................eaaaaaealeaalaalrarlralrra 292
                 ++r++ar l   + ++   ++++ s+ +l    ++ee++ + +++ ll++ ++l                   + ++  +++++ l + r++l++l+++
  EEA20554.1  11 QLRQQARSLETQTEALFHTYSQYASMSQLPPKPSEEEQRIESQIQSLLEKRESLigqltrlldseatltssalK-QNNLARHREVLSEHRRELNRLSSS 108
                 56777777777777777777888888888888888888887779999999999999999999997666654421.233444444444444444444444 PP

        FUSC 293 leadadtaalllarlaellaelaqlla 319
                  + +a  +a ll+++++++++++  + 
  EEA20554.1 109 IS-EARDRANLLSNVRSDIDAYRSSNP 134
                 44.666666667777777776665544 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   9.7    0.0066       9.9      15     119 ..      13     116 ..       9     122 .. 0.68
   2 ?    1.7   1.5      0.23   3.5e+02      44      86 ..      87     132 ..      74     162 .. 0.65

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0066
      APG6_N  15 dkqleqaekerdaYeeflkklkkekkeeekqdeeleeleeeleklekeeeelleeLkelekereeleaelaaleeelealeeeeerfwreynelqlell 113
                  +q +++e + +a+    ++  + ++ + k  ee++++e +++ l +++e+l+ +L +l + ++ l +   ++ + l++  e   ++ re n l+   +
  EEA20554.1  13 RQQARSLETQTEALFHTYSQYASMSQLPPKPSEEEQRIESQIQSLLEKRESLIGQLTRLLDSEATLTSSALKQ-NNLARHREVLSEHRRELNRLSSSIS 110
                 45555555555544444444444444433356799******************************99876654.4455555556777788888888777 PP

      APG6_N 114 eleeel 119
                 e  ++ 
  EEA20554.1 111 EARDRA 116
                 777765 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.23
      APG6_N  44 k...qdeeleeleeeleklekeeeelleeLkelekereeleaelaa 86 
                 +   ++e l e ++el +l++  +e+    + l + r++++a +++
  EEA20554.1  87 NlarHREVLSEHRRELNRLSSSISEARDRANLLSNVRSDIDAYRSS 132
                 1233566777777777777777777777777777777777766554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (227 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1151  (0.0641977); expected 358.6 (0.02)
Passed bias filter:                      610  (0.0340231); expected 358.6 (0.02)
Passed Vit filter:                        74  (0.00412739); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.55u 0.31s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 1495.19
//
Query:       EEA20555.1  [L=321]
Description: F1F0 ATP synthase assembly protein Atp10, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      1e-83  280.5   0.0    1.3e-83  280.2   0.0    1.0  1  ATP-synt_10  ATP10 protein


Domain annotation for each model (and alignments):
>> ATP-synt_10  ATP10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  280.2   0.0   7.1e-88   1.3e-83       6     254 ..      43     288 ..      35     291 .. 0.95

  Alignments for each domain:
  == domain 1  score: 280.2 bits;  conditional E-value: 7.1e-88
  ATP-synt_10   6 askpkeekvkeltrpiGldkppsknent.skkyslgnslkdlfdeektekrrkeLeeelkksyfydlkefrktnGKlFlspksyfkadkalyfPnlvG 102
                  +++p++ ++ el+rpiGl+ pp +++nt  +++sl+++++d++d +k+ +rrkeL+ +l+k+yf++++++++++GK+F s++++fk+dkal+fPnl+G
   EEA20555.1  43 KEQPDNVQPIELDRPIGLPYPPLPGQNTgLDHRSLSERRDDFVDWQKHLQRRKELTTHLAKPYFREWTNLKYNEGKTFRSNPRLFKHDKALFFPNLYG 140
                  4556667799*******************9******************************************************************** PP

  ATP-synt_10 103 ktLa.sskeqsledvlkgkvsvVrlfssvvgeelvksyfknkeegkdylkdyeelkeenkdlQivdinlienwlKallvklslaslrkklpkerhnky 199
                   tL+ ++k q++++++kgk+svV+lfss ++e++v++++k++    +  + ye+l+ + +++Q v+in++en+lKa+l++l+++++r+k+p+++h+ky
   EEA20555.1 141 VTLEsPKKPQDTTNIIKGKISVVSLFSSLWAEQQVATFTKRQ----NNPQLYETLEANPSTTQRVEINIEENRLKAWLIRLFMGNMRRKMPRDQHDKY 234
                  ****99**********************************33....555889********************************************** PP

  ATP-synt_10 200 fivsrkqlpfeireelkinNlytGYvylvDqnlkIRWagsGnateeelellwkcv 254
                  f+v +k+++++i+++++++N+++GYvyl+D+ ++IRWagsG+a+++e + l+ ++
   EEA20555.1 235 FLV-QKGMTDSIKQAIGMLNSKVGYVYLLDDYGHIRWAGSGSAEPSERDSLNAGL 288
                  ***.999********************************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (321 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       607  (0.0338558); expected 358.6 (0.02)
Passed bias filter:                      479  (0.0267165); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.67u 0.34s 00:00:01.01 Elapsed: 00:00:00.57
# Mc/sec: 1710.08
//
Query:       EEA20556.1  [L=628]
Description: DNA polymerase POL4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.6e-35  120.6   0.0    7.1e-35  119.7   0.0    1.5  1  DNA_pol_B_palm   DNA polymerase beta palm
    7.9e-24   83.6   0.1    2.1e-23   82.3   0.0    1.8  2  DNA_pol_B_thumb  DNA polymerase beta thumb
    4.9e-20   71.7   1.6      1e-19   70.6   1.6    1.6  1  HHH_8            Helix-hairpin-helix domain
    5.1e-19   67.8   0.3    1.8e-18   66.1   0.2    2.1  2  DNA_pol_lambd_f  Fingers domain of DNA polymerase lambda
      1e-06   29.0   0.0    2.4e-06   27.8   0.0    1.7  1  BRCT             BRCA1 C Terminus (BRCT) domain
    0.00045   20.6   0.1     0.0018   18.6   0.0    2.1  3  BRCT_2           BRCT domain, a BRCA1 C-terminus domain
     0.0059   16.9   0.0      0.014   15.7   0.0    1.6  1  NTP_transf_2     Nucleotidyltransferase domain
  ------ inclusion threshold ------
      0.088   12.8   0.0       0.25   11.3   0.0    1.7  1  PTCB-BRCT        twin BRCT domain


Domain annotation for each model (and alignments):
>> DNA_pol_B_palm  DNA polymerase beta palm
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.7   0.0   3.2e-38   7.1e-35       1     113 [.     438     548 ..     438     549 .. 0.94

  Alignments for each domain:
  == domain 1  score: 119.7 bits;  conditional E-value: 3.2e-38
                     -EEHHHHHHHHHHHHHHHHHH-TT-EEEE-HHHHTT-SEESSEEEEEEBTTBSTTSS--HHHHHHHHHHHHHTTSEEEEEE..E-..SSEEEEEE CS
  DNA_pol_B_palm   1 riPreEvealealvkkaakeldpevevivcGSYRRgaessGDvDvlitkkdakseskklkklleklvkklkkkgfltdsLavesg..eskfmGvc 93 
                     riPr+Ev+++ + v++a++++dp++ev+v+GSYRRga+++GD+D+litk++++ e   ++ +++++v +l+kkgfl++sLa++s+  +sk++G++
      EEA20556.1 438 RIPRAEVAKHGESVREAVHAIDPDMEVMVTGSYRRGAADCGDIDILITKTNGTIEY-IRTLMMDNVVPELTKKGFLKASLATTSRgdGSKWHGAS 531
                     9*****************************************************65.899*********************944346******** PP

                     E---SSSTS-EEEEEEEEE- CS
  DNA_pol_B_palm  94 rlpeeekkelhrRiDlklvp 113
                     +lp++    l+rRiDl++vp
      EEA20556.1 532 ALPGT---DLWRRIDLLFVP 548
                     ****4...6*********98 PP

>> DNA_pol_B_thumb  DNA polymerase beta thumb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0       5.5   1.2e+04      39      60 ..      41      63 ..      22      68 .. 0.55
   2 !   82.3   0.0   9.2e-27   2.1e-23       2      70 .]     556     627 ..     555     627 .. 0.94

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 5.5
                     .ETCCCEEEC-.SSHHHHHHHCT CS
  DNA_pol_B_thumb 39 eddddgelvev.etErdvfelLg 60
                     ++++  + v++  +  ++f++L 
       EEA20556.1 41 RKKRRTQSVQIiPETNQIFKGLT 63
                     33333334444356667888886 PP

  == domain 2  score: 82.3 bits;  conditional E-value: 9.2e-27
                      HHHHHS-HHHHHHHHHHHHCTTEEEETTEEE...........ETCCCEEEC-SSHHHHHHHCTS----GGGTT CS
  DNA_pol_B_thumb   2 llyfTGsktFnrdlRrlakkkglkLnssglrdek....gkaeddddgelvevetErdvfelLglpyipPeeRe 70 
                      llyfTG++ Fnr+ R+la+kkg++Ln++gl++ +     ++++ +dg+l+e+++E+++ e+Lg+p++pP++R+
       EEA20556.1 556 LLYFTGNDIFNRSVRLLARKKGMRLNQHGLYK-DvlrgPNQAKLTDGTLLEGRDEKRILEILGVPWRPPQHRN 627
                      8******************************6.246778999******************************7 PP

>> HHH_8  Helix-hairpin-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.6   1.6   4.6e-23     1e-19       1      67 [.     303     367 ..     303     368 .. 0.96

  Alignments for each domain:
  == domain 1  score: 70.6 bits;  conditional E-value: 4.6e-23
                 HHHHHHHHHHHHHHHHHCT--CCCHHHHHHHHCCCCC-SS-HHHHTTHCTTSTT--HHHHHHHHHHH CS
       HHH_8   1 NkeiadaLeeladllelkgedpfrvraYrrAaraiealpeeitsleeeltklpgiGkkiaakieeil 67 
                 N++ +++L+++ad+++++ +d++r  aYr+A++a+++++ +i++ +e + ++pgiG+++a+kieei+
  EEA20556.1 303 NAKTIEILQKMADYYDRT-ADTWRTMAYRKAIAALRKQKAKICTKAE-ALAIPGIGQRLADKIEEIV 367
                 8999**************.*************************655.******************8 PP

>> DNA_pol_lambd_f  Fingers domain of DNA polymerase lambda
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       4.1   9.3e+03       6      16 ..     352     362 ..     351     363 .. 0.85
   2 !   66.1   0.2   8.2e-22   1.8e-18       1      50 []     388     436 ..     388     436 .. 0.98

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 4.1
  DNA_pol_lambd_f   6 vyGVGpktAkk 16 
                      + G+G++ A k
       EEA20556.1 352 IPGIGQRLADK 362
                      78****99987 PP

  == domain 2  score: 66.1 bits;  conditional E-value: 8.2e-22
  DNA_pol_lambd_f   1 qlFtkvyGVGpktAkkwyakGirtledlrakrakLtreqqiGlkyyeDlq 50 
                      qlF++vyG G ++A+kw+akG+r+ledl++ +a+Lt +q+iG++ y+D+q
       EEA20556.1 388 QLFLGVYGAGFAQASKWVAKGYRSLEDLKN-KAELTTNQKIGVERYNDFQ 436
                      79****************************.6*****************8 PP

>> BRCT  BRCA1 C Terminus (BRCT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0   1.1e-09   2.4e-06       3      79 .]      56     137 ..      54     137 .. 0.87

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 1.1e-09
                 TTTTTTEEEEE.EESTSSHHHHHHHHHHHHTTCEEESSCSTTSSEEEESSS....HSHHHHHHHHHHTTSEEEETHHHHHHH CS
        BRCT   3 ellfhgckfvi.tgvldnftrdeleelikehGGkvttevskktthlvvgep....esrslkylealklnipivheewlldci 79 
                   +f+g++f++ +++  +  r    +  +e+G++  + +s+++th++v++     e  +    e+l+ ni iv+ +++ dc+
  EEA20556.1  56 NQIFKGLTFFFvPNNDISPARRLRIQRSQEYGASWAQTWSSDVTHVIVDKGldyrEMLKVLTPEQLSANIAIVNQDYVSDCL 137
                 679********988888888888899*************************7755333344779*****************7 PP

>> BRCT_2  BRCT domain, a BRCA1 C-terminus domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0   8.2e-07    0.0018       2      73 ..      56     137 ..      55     147 .. 0.88
   2 ?   -2.9   0.0       4.2   9.5e+03      29      51 ..     291     313 ..     287     326 .. 0.76
   3 ?   -4.1   0.0         8   1.8e+04      24      36 ..     480     492 ..     474     500 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 8.2e-07
      BRCT_2   2 sklFeglrFYin.daeps.psreklkklIeknGGevvetitsavyiviaesneee.........laekrkrrvvspkyIkdCi 73 
                 +++F+gl+F+ + ++  s + r ++++  +++G    +t +s+v++vi+ +  +          ++ +++  +v+ +y+ dC+
  EEA20556.1  56 NQIFKGLTFFFVpNNDISpARRLRIQRS-QEYGASWAQTWSSDVTHVIVDKGLDYremlkvltpEQLSANIAIVNQDYVSDCL 137
                 68*********87556663777777777.**********************98889**************************7 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 4.2
      BRCT_2  29 eknGGevvetitsavyiviaesn 51 
                 +k++G+ +++  +a++i i ++ 
  EEA20556.1 291 QKHDGNSSNNNPNAKTIEILQKM 313
                 68899999999888888877765 PP

  == domain 3  score: -4.1 bits;  conditional E-value: 8
      BRCT_2  24 lkklIeknGGevv 36 
                 +  lI+k +G+++
  EEA20556.1 480 IDILITKTNGTIE 492
                 5568999999985 PP

>> NTP_transf_2  Nucleotidyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   6.3e-06     0.014       4      39 ..     451     485 ..     449     508 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 6.3e-06
                   HHHHHHHHTTTSEEEEEHHHHCTTSCTTSSEEEEEE CS
  NTP_transf_2   4 lleelkelepvakvvlfGSyarGtalkgSDiDllvv 39 
                   ++e++   +p+ +v ++GSy+rG a    DiD+l++
    EEA20556.1 451 VREAVHAIDPDMEVMVTGSYRRGAAD-CGDIDILIT 485
                   7899999999**************77.58*****97 PP

>> PTCB-BRCT  twin BRCT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00011      0.25      21      43 ..      84     106 ..      71     108 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00011
                 HHTT-EEESSEETT-SEEEECSS CS
   PTCB-BRCT  21 eamGaeyskdltksvTHLicksg 43 
                 ++ Ga+  ++++ +vTH+i+ +g
  EEA20556.1  84 QEYGASWAQTWSSDVTHVIVDKG 106
                 689****************9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (628 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       847  (0.0472419); expected 358.6 (0.02)
Passed bias filter:                      544  (0.0303419); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.76u 0.32s 00:00:01.08 Elapsed: 00:00:00.54
# Mc/sec: 3485.46
//
Query:       EEA20557.1  [L=901]
Description: hypothetical protein PMAA_043900 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (901 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       489  (0.0272742); expected 358.6 (0.02)
Passed bias filter:                      447  (0.0249317); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.70u 0.31s 00:00:01.01 Elapsed: 00:00:00.46
# Mc/sec: 5855.55
//
Query:       EEA20558.1  [L=141]
Description: hypothetical protein PMAA_043910 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (141 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       299  (0.0166769); expected 358.6 (0.02)
Passed bias filter:                      272  (0.015171); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.27s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 997.88
//
Query:       EEA20559.1  [L=725]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0075   16.4   7.2      0.019   15.1   7.2    1.8  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.011   15.7   0.2      0.026   14.5   0.2    1.6  1  zf-BED    BED zinc finger
       0.04   13.9   0.8        0.1   12.6   0.2    1.9  2  HbrB      HbrB-like


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   7.2   3.2e-06     0.019       2      27 ..     327     351 ..     326     365 .. 0.92

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 3.2e-06
                 S-HHHHHCT---STSSSS-HHHHHCT CS
     Zn_clus   2 aCdnCrkkKvKCdakkPaCsnCkkln 27 
                 aC++Cr  K  C+++ P C+ C++++
  EEA20559.1 327 ACIRCRMLKKPCSGDSP-CQTCASVE 351
                 9****************.****9865 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.2   4.4e-06     0.026      13      44 .]      24      54 ..       9      54 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 4.4e-06
                GSS--EETTTTEE----SSTHHHHHHHHHS-H CS
      zf-BED 13 keqkavCryCgkilsrgggttnLkrHLrrkHp 44
                 +   +C+ Cg+++  g  +  L +HL++k++
  EEA20559.1 24 NRYQHTCKACGEKFPKG-RIDSLTTHLVKKCQ 54
                566779**********9.*************7 PP

>> HbrB  HbrB-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.2   1.7e-05       0.1      47      89 ..     469     511 ..     459     522 .. 0.85
   2 ?   -2.1   0.0      0.54   3.2e+03      46      86 ..     555     595 ..     545     604 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.7e-05
        HbrB  47 alsllvedleeLlstglltLenkLsqleeerllkrLveiWkff 89 
                  +s+++e+ ++ + +++ltL++ L  +++++ll r+ve+W ++
  EEA20559.1 469 LQSTFIEHETSPIIKSTLTLAAHLADEKKDTLLDRVVELWLVT 511
                 5667888888889999************************986 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.54
        HbrB  46 kalsllvedleeLlstglltLenkLsqleeerllkrLveiW 86 
                  + +l+ + l+  +++  + L+++++++ e rll+r    W
  EEA20559.1 555 DSYNLICSQLRAAVEKRASLLSKNVMNELERRLLQRHHSGW 595
                 57778888888888888888888888888888888877777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (725 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       498  (0.0277762); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.61u 0.27s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 4778.44
//
Query:       EEA20560.1  [L=849]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (849 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       892  (0.0497518); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.74u 0.28s 00:00:01.02 Elapsed: 00:00:00.48
# Mc/sec: 5322.26
//
Query:       EEA20561.1  [L=703]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.5e-30  104.9   0.0    1.6e-28   99.9   0.0    3.3  4  CPL          CPL (NUC119) domain
  ------ inclusion threshold ------
       0.29    9.2  20.1       0.84    7.7  20.1    1.9  1  DNA_pol_phi  DNA polymerase phi
       0.88    7.8  18.9        1.4    7.2  18.9    1.3  1  CDC45        CDC45-like protein
        1.1    8.8   9.6         60    3.1   0.0    2.4  2  VIR_N        Virilizer, N-terminal
        1.3    7.1  29.3        1.8    6.6  29.3    1.2  1  Nop14        Nop14-like family
        1.5    8.4  24.6        2.8    7.5  24.6    1.4  1  BSP_II       Bone sialoprotein II (BSP-II)
        4.1    6.1  11.9        6.3    5.5  11.9    1.3  1  Presenilin   Presenilin


Domain annotation for each model (and alignments):
>> CPL  CPL (NUC119) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0      0.25   6.3e+02      53      99 ..     181     224 ..     159     290 .. 0.83
   2 ?   -2.4   0.0       2.2   5.6e+03      93     105 ..     372     384 ..     323     433 .. 0.58
   3 !   99.9   0.0   6.1e-32   1.6e-28       2     143 .]     480     611 ..     479     611 .. 0.94
   4 ?   -3.1   0.0       3.6   9.3e+03      87      94 ..     664     671 ..     625     689 .. 0.56

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.25
         CPL  53 eaispallsaiaknaeellsdnlgsqfvaevLlsaegdkqeaieaia 99 
                 +++  +l + i+  +++++ +  +  +++ +L++a+ +++++i   +
  EEA20561.1 181 KKLVAELFEIITGRVDDFVFKHDSVRVIQTALKYASLEQRKMI---V 224
                 6777889999999999999999999999999999999888766...3 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 2.2
         CPL  93 eaieaiaklakgd 105
                 +  +++++l+kgd
  EEA20561.1 372 SEANEFIELIKGD 384
                 3334444555555 PP

  == domain 3  score: 99.9 bits;  conditional E-value: 6.1e-32
         CPL   2 dkygRrvllYllsgrdgryfspev.iklLkegdelakktSKKdaevRrkELleaispallsaiaknaeellsdnlgsqfvaevLlsaegdkqeaieaia 99 
                 d  +R + lY ++g   + + p+   ++L+e+ e++k+tSKK++ +Rr+EL++a+sp+ll+ ia+ ae+l+ +++g+qf++evL sa+gdk+ a++a+a
  EEA20561.1 480 DIIARVPVLYPFVGDKVKWLLPAGdEDILNEIFEIRKETSKKEPSIRRQELVQAASPSLLEFIAARAESLMETSFGCQFLSEVLFSADGDKSAALNAVA 578
                 567999********99999999886889*********************************************************************** PP

         CPL 100 klakgdlvaeekdeelhliekpfgsrlLKaLiqgdeekwenkek 143
                  +ak +     ++ +    + pf++r+LK+L+qg+  +++n+ek
  EEA20561.1 579 VAAKSK-----IEAQ----DSPFVGRMLKSLVQGG--RYNNAEK 611
                 ***999.....5555....78**************..9999876 PP

  == domain 4  score: -3.1 bits;  conditional E-value: 3.6
         CPL  87 aegdkqea 94 
                 + +++++a
  EEA20561.1 664 TLKKNKKA 671
                 22222233 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7  20.1   0.00033      0.84     631     704 ..      65     129 ..      51     222 .. 0.66

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00033
  DNA_pol_phi 631 kegqaelfedededeeddeeeeeeddeededseedddeeesdedeededdedvdeidelreklaealgesgede 704
                  k+gq +  + e+++eedd++ +++ +++++d++ ddd ++s+  ee+e +e+++e      + ++ +g+++  +
   EEA20561.1  65 KKGQYKK-KYEEDEEEDDDDMNSDISSDESDVSMDDDVDDSEPVEEEEAEEEEEE------ETENSNGDVN--A 129
                  2222221.22333333333333333444444444444444444444333333333......4444444444..2 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2  18.9   0.00053       1.4     122     208 ..      68     151 ..      37     229 .. 0.48

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.00053
       CDC45 122 ayealeeeeesdeede.............eeeeeddddeeeeeeeeedeedeeedeeeskkkrksksdeeee..sddddersrkrrrsepsakklrrql 205
                 +y++  ee+e++++d+               +++ dd+e  eeee e+ee+ee+++               +  + ++d++s++r+ +  ++k+l ++ 
  EEA20561.1  68 QYKKKYEEDEEEDDDDmnsdissdesdvsM-DDDVDDSEPVEEEEAEEEEEEETEN---------------SngDVNADNKSSSRESHA-KQKALAQE- 148
                 333333333332222222222222111210.1111111111111111111111111...............111111222222222222.11111111. PP

       CDC45 206 kke 208
                 +k+
  EEA20561.1 149 RKA 151
                 111 PP

>> VIR_N  Virilizer, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2  12.9      0.24   6.3e+02     188     250 ..      59     121 ..      15     173 .. 0.49
   2 ?    3.1   0.0     0.023        60     115     217 ..     438     536 ..     436     552 .. 0.81

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.24
       VIR_N 188 eedaavpetveeekeensek..redyleeesPeertslkaeekdseaereeresseeierdeees 250
                 e++++ ++ + ++k+e+ e+   +d+  ++s  +++ ++ ++++ ++e  e+e+ ee e++e  +
  EEA20561.1  59 EKKKPSKKGQYKKKYEEDEEedDDDMNSDISS-DESDVSMDDDVDDSEPVEEEEAEEEEEEET-E 121
                 33333333222222222222011222222222.222333333222222222211111111111.1 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.023
       VIR_N 115 ltlavYGtvervlsedrvsipPppPapPvkelekedqynaspvrpeprePrtpelipaytgnvastpPpdddeeedaavpetveeekeensekredyle 213
                 + la YG+++ +     +si P       +e+e+  ++++  ++ ++   r+p l p   ++v    P  d++  +   +   e++k+e s++r++ ++
  EEA20561.1 438 VILAAYGVIDDT-KLSSKSIFP---ELLNQETEETARHEELLLQINDIIARVPVLYPFVGDKVKWLLPAGDEDILNEIFEIRKETSKKEPSIRRQELVQ 532
                 579999999987.334444444...4445678888999999999999999999999999999999999888888888999999999************* PP

       VIR_N 214 eesP 217
                 + sP
  EEA20561.1 533 AASP 536
                 ***9 PP

>> Nop14  Nop14-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6  29.3   0.00072       1.8     313     422 ..      24     152 ..       1     184 [. 0.36

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.00072
       Nop14 313 e.......................asaDdldddfvleeeeeeeefglgkglkataeeeeeededdfeedddlveseseeeeeeeeedeeeeedeeeee. 387
                 +                        s+D    +   ++ e+++  +  kg   +++ ee+e+edd++ ++d +++es+++ +++ +d+e  e+ee+ee 
  EEA20561.1  24 NiaptavgtkstfqkkgitagarkMSGD----KKLSKQAEKKKPSK--KGQY-KKKYEEDEEEDDDDMNSDISSDESDVSMDDDVDDSEPVEEEEAEEe 115
                 2443333333333333333221111111....11222211111111..1221.2223344444444444444444454444222222222222222221 PP

       Nop14 388 eeeededdlsdleseeeeeedeleeel..leeekkaa 422
                 eeee e+++ d ++++++++ e + ++  l++e+kaa
  EEA20561.1 116 EEEETENSNGDVNADNKSSSRESHAKQkaLAQERKAA 152
                 3333333333333333333333211111233333322 PP

>> BSP_II  Bone sialoprotein II (BSP-II)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5  24.6    0.0011       2.8      81     223 ..      12     148 ..       3     170 .. 0.52

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0011
      BSP_II  81 enedeeseaenttlsattpgygeektqgkgsiGlaaiklpkkagdieekatkeeesdeeeeeeeeeeneeeeaevdeneqgvngtstnsteaengngss 179
                 ++++ ++   +t +++t  g+ +  +++  + G  ++   kk     ++a+k++ s++ + +++  e++eee++ d n +     s  s + + ++++ 
  EEA20561.1  12 DDRNGKRTKTKTNIAPTAVGTKSTFQKKGITAGARKMSGDKKLS---KQAEKKKPSKKGQYKKK-YEEDEEEDDDDMNSDISSDESDVSMDDDVDDSEP 106
                 33334444445555565555555554444455555555555544...44444444444443333.3334444455777777777777777766665555 PP

      BSP_II 180 ggdnge.eeeeesvteaeaegteveeeeeagsaetttspnglfea 223
                   +++e eeeee++te +++  +v+++++++s+e+ +++++l + 
  EEA20561.1 107 V-EEEEaEEEEEEETE-NSN-GDVNADNKSSSRESHAKQKALAQE 148
                 5.44441444444443.444.455666666777777777766653 PP

>> Presenilin  Presenilin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5  11.9    0.0024       6.3     229     304 ..      51     141 ..      33     215 .. 0.55

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0024
  Presenilin 229 kaevaeseeeeeaekkkeeasesskeeeseeesseksaqsse................seeeseeesseaessaeesseekeseessessee 304
                 +++ ++++e+++ +kk + +++++++ee++++  ++  +s+e                + ee+eee++e++++++   + +++++s+es+++
  EEA20561.1  51 DKKLSKQAEKKKPSKKGQYKKKYEEDEEEDDDDMNSDISSDEsdvsmdddvddsepveE-EEAEEEEEEETENSNGDVNADNKSSSRESHAK 141
                 44445555555556666666666666655554444444444445555555555444321.11111111111111111111111111111111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (703 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1696  (0.0945953); expected 358.6 (0.02)
Passed bias filter:                      561  (0.0312901); expected 358.6 (0.02)
Passed Vit filter:                       123  (0.00686039); expected 17.9 (0.001)
Passed Fwd filter:                        27  (0.00150594); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.98u 0.34s 00:00:01.32 Elapsed: 00:00:00.52
# Mc/sec: 4089.57
//
Query:       EEA20562.1  [L=173]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (173 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       399  (0.0222544); expected 358.6 (0.02)
Passed bias filter:                      180  (0.0100396); expected 358.6 (0.02)
Passed Vit filter:                         9  (0.00050198); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.27s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 1231.74
//
Query:       EEA20563.1  [L=126]
Description: hypothetical protein PMAA_043960 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        0.2   11.9   0.0       0.69   10.2   0.0    1.7  2  DUF4090   Protein of unknown function (DUF4090)


Domain annotation for each model (and alignments):
>> DUF4090  Protein of unknown function (DUF4090)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   3.9e-05      0.69      20      44 ..      28      52 ..      12      70 .. 0.78
   2 ?   -0.2   0.0     0.068   1.2e+03       7      21 ..      66      80 ..      64      84 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 3.9e-05
     DUF4090 20 ipaeklelykevmaleakrqrsGvk 44
                ++++k++ly++  a ea r rs v+
  EEA20563.1 28 MNRRKVKLYNQAFADEAGRIRSIVS 52
                56789*****************997 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.068
     DUF4090  7 eaiakGidldGspip 21
                +a+++G+ +dG   p
  EEA20563.1 66 RALESGVQVDGIYTP 80
                58999*****97655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (126 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       332  (0.0185175); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.37u 0.23s 00:00:00.60 Elapsed: 00:00:00.37
# Mc/sec: 1013.12
//
Query:       EEA20564.1  [L=349]
Description: DNA repair protein RAD51, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.6e-129  429.9   0.0   3.2e-129  429.7   0.0    1.1  1  Rad51     Rad51
    1.9e-10   40.6   0.0    2.8e-10   40.1   0.0    1.2  1  AAA_25    AAA domain
    2.1e-09   37.2   0.0    2.9e-09   36.8   0.0    1.1  1  RecA      recA bacterial DNA recombination protein
    3.6e-06   27.5   0.9      1e-05   26.0   0.4    2.0  2  HHH_5     Helix-hairpin-helix domain
    2.6e-05   23.7   0.6    0.00011   21.6   0.6    2.0  1  ATPase    KaiC
     0.0017   17.7   0.2       0.02   14.3   0.0    2.1  2  DnaB_C    DnaB-like helicase C terminal domain
  ------ inclusion threshold ------
      0.023   15.0   0.3      0.099   12.9   0.3    2.0  1  AAA_22    AAA domain
      0.038   13.1   0.4       0.33   10.1   0.1    2.0  2  PAXNEB    PAXNEB protein


Domain annotation for each model (and alignments):
>> Rad51  Rad51
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  429.7   0.0  1.4e-132  3.2e-129       1     254 [.      86     340 ..      86     341 .. 0.99

  Alignments for each domain:
  == domain 1  score: 429.7 bits;  conditional E-value: 1.4e-132
                 -S-EBHHHHHHHHHSS-EE--S-HHHHHHHTSSEESSSEEEEEESTTSSHHHHHHHHHHHTTS-TTTS--SSEEEEEESSS---GGGGHHHHHHTT--H CS
       Rad51   1 lgfvsavellekrsellqlttGskklDelLgGGietgsiteifGefrsGktqlchtlcvtvqlplelgGgegkavyidtegtfrperlveiaerykldk 99 
                 +gf++a+e++++rsel+++ttGsk+lD+lL GGietgsiteifGefr+Gk+qlchtl+vt+qlp ++gGgegk++yidtegtfrp rl+++a+ry+l +
  EEA20564.1  86 MGFTTATEMHARRSELISITTGSKQLDTLLAGGIETGSITEIFGEFRTGKSQLCHTLAVTCQLPFDMGGGEGKCLYIDTEGTFRPVRLLAVAQRYGLVG 184
                 79************************************************************************************************* PP

                 HHHGGGEEEEE--STTHHHHHHHHTHHHHHHS-EEEEEEETTTGGGCH-------THHHHHHHHHHHHHHHHHHHHH--EEEEEEE-------..---- CS
       Rad51 100 eevlenvayaRaytiehqeellqqaaallaedkfallivDsvtalyRtdfsgrgelakRqqklgkllrtLrkladefevavvitnqvvaqvdgq.aalf 197
                 eevl+nvayaRay+++hq +ll+qa+++++e++f+llivDs+talyRtdf+grgel++Rq++l+k+lrtL++ladef++avvitnqvv+qvdg  +++f
  EEA20564.1 185 EEVLDNVAYARAYNSDHQLQLLNQASQMMCETRFSLLIVDSATALYRTDFNGRGELSNRQTHLAKFLRTLQRLADEFGIAVVITNQVVSQVDGGpSSMF 283
                 *******************************************************************************************985389** PP

                 --------HHHHHHHH-SEEEEEEE-STTEEEEEEES-SSS-S-EEEEEEETTEEE- CS
       Rad51 198 sadpkkPigGlvlahasttRlalrkgkgeeRivkvvdsPnlpeleavfaigeeGied 254
                 ++dpkkPigG+++ahasttRl+l+kg+ge+Ri+k++dsP+lpe+++ fai e+Gi d
  EEA20564.1 284 NPDPKKPIGGNIIAHASTTRLSLKKGRGETRICKIYDSPCLPESDCLFAIREDGIGD 340
                 *******************************************************98 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.1   0.0   1.3e-13   2.8e-10       5     188 ..      94     270 ..      90     273 .. 0.81

  Alignments for each domain:
  == domain 1  score: 40.1 bits;  conditional E-value: 1.3e-13
      AAA_25   5 lelsavsvadlaapppprrwlvkgllpagelallaGapgtGKttlaldlalavatGkpwlgpvapeqgkVlyvsaEdsedelrrRlravgealrddarl 103
                 + ++ ++   + +  ++++ l+ g +  g+++ ++G   tGK+ l+  la+++ +  p+  ++    gk+ly+++E++    + Rl av + + + +++
  EEA20564.1  94 MHARRSELISITTGSKQLDTLLAGGIETGSITEIFGEFRTGKSQLCHTLAVTCQL--PF--DMGGGEGKCLYIDTEGTF--RPVRLLAVAQRYGLVGEE 186
                 555666677777888899999**99************************999985..77..47779************8..799*********999999 PP

      AAA_25 104 lvldlagveslpLfakdrggtlltadvdaleaaieevegvrlvviDplsralggdensnsd.....v..galvealeriarrtgaavllvhH 188
                  + ++a     + + +d++ +ll+++     + + e  +  l+++D+ +++++ d n   +     +  ++++  l+r+a+++g+av+++ +
  EEA20564.1 187 VLDNVAYA---RAYNSDHQLQLLNQA----SQMMCE-TRFSLLIVDSATALYRTDFNGRGElsnrqThlAKFLRTLQRLADEFGIAVVITNQ 270
                 99998775...556656666556555....333344.349**********9999766665555555455*******************9865 PP

>> RecA  recA bacterial DNA recombination protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.8   0.0   1.3e-12   2.9e-09      27     221 ..      97     308 ..      75     317 .. 0.74

  Alignments for each domain:
  == domain 1  score: 36.8 bits;  conditional E-value: 1.3e-12
                 .-----EE--S-HHHHHHTSSSSEETTSEEEEEESTTSSHHHHHHHHHHHHH......HTT--EEEEESS----HH....HHHHTT--GGG-E....EE CS
        RecA  27 eklkvetissGslaldialGiGGlpkGriieiyGpessGkttlalhaiaeaq......kkggvaafidaehaldpk....yakklGvdidell....vs 111
                 ++ ++ +i++Gs +ld+ l  GG+  G i+ei+G   +Gk+ l+  + + +q         g + +id+e ++ p+     a++ G+  +e+l     +
  EEA20564.1  97 RRSELISITTGSKQLDTLLA-GGIETGSITEIFGEFRTGKSQLCHTLAVTCQlpfdmgGGEGKCLYIDTEGTFRPVrllaVAQRYGLVGEEVLdnvaYA 194
                 35678899********9887.********************9965555555522321123579**********99633336899998655544221155 PP

                 ...--SSHHHHHHHHHHHHTTT--SEEEEE-TTT---STT---..--------HHHHHHHHHHHHHHHHHTTT--EEEEEEE-----..-..----.-- CS
        RecA 112 ...qpdtGeqaleiadalvrsgaidlivvdsvaalvpkaeieG..emgdskvglqarlmsqalrkltgaisksntvvifinqireki..G..vmfg.np 200
                    + d+  q l+ a +++  +   l++vds +al  +++ +G  e+++     q+  +++ lr l+   ++  ++v+  nq+  ++  G   mf  +p
  EEA20564.1 195 rayNSDHQLQLLNQASQMMCETRFSLLIVDSATALY-RTDFNGrgELSNR----QT-HLAKFLRTLQRLADEFGIAVVITNQVVSQVdgGpsSMFNpDP 287
                 2224566667777788899999************97.6677761144443....44.457899********************9999541435665588 PP

                 -----HHHHHHH-SEEEEEEE CS
        RecA 201 etttGGralkfyasvrldvrr 221
                 +   GG+ +   ++ rl +++
  EEA20564.1 288 KKPIGGNIIAHASTTRLSLKK 308
                 9999***99999999999887 PP

>> HHH_5  Helix-hairpin-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0   0.4   4.7e-09     1e-05       4      56 ..      29      81 ..      27      82 .. 0.94
   2 ?   -2.5   0.0       3.6     8e+03      29      47 ..     296     314 ..     295     320 .. 0.78

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 4.7e-09
                HHTSTT--HHHHHHHHTTT--SHHHHHHS-HHHHHTSTTS-HHHHHHHHHHHH CS
       HHH_5  4 LlsvsGiGpktAlallsaGiesvedlaaadveeLakipGiGkktAeriilelk 56
                L +v G+ +++++ ++++G+ +ve +a   +  L +i+Gi++ +A +i+ e+ 
  EEA20564.1 29 LEGVAGLTARDIKLIVDGGFHTVESVAYTPKRVLEQIKGISEQKATKILAEAS 81
                889*************************99999****************9986 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 3.6
                 HHHS-HHHHHTSTTS-HHH CS
       HHH_5  29 laaadveeLakipGiGkkt 47 
                 +a+a++ +L+  +G G+ +
  EEA20564.1 296 IAHASTTRLSLKKGRGETR 314
                 8999999999888888766 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.6   0.6   5.1e-08   0.00011       2     131 ..     105     229 ..     104     318 .. 0.67

  Alignments for each domain:
  == domain 1  score: 21.6 bits;  conditional E-value: 5.1e-08
      ATPase   2 ktgIeglDeilkgGipegrvvlitGepGtGKtifalqFlikgaekyge.....pgvfvtveepa..edlrenakslGwdlekleeegklaiidasesae 93 
                  tg + lD++l gGi  g+++ i Ge  tGK+ ++ + +++    ++      +++++ +e +   + l   a++ G   e++ ++  +a+  a++s++
  EEA20564.1 105 TTGSKQLDTLLAGGIETGSITEIFGEFRTGKSQLCHTLAVTCQLPFDMgggegKCLYIDTEGTFrpVRLLAVAQRYGLVGEEVLDN--VAYARAYNSDH 201
                 7999********************************99998765543211223788888887654467777777777777777777..55555555543 PP

      ATPase  94 esaeekdkedleelieelaeaikeikakrvviDsitgl 131
                 +           +l+++  +++ e++ + +++Ds t+l
  EEA20564.1 202 Q----------LQLLNQASQMMCETRFSLLIVDSATAL 229
                 3..........456677777777777777777777777 PP

>> DnaB_C  DnaB-like helicase C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0     0.081   1.8e+02       2      42 ..     104     145 ..     103     153 .. 0.86
   2 !   14.3   0.0   8.8e-06      0.02     116     182 ..     204     275 ..     187     282 .. 0.81

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.081
                 BXSSTHHHHHHC.TSBXTTXEEEEEEXTTSSHHHHHHHHHHH CS
                 xxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      DnaB_C   2 lstgfkdLDklt.sGlqkgdliiiAarpsmGktalalniaen 42 
                 ++tg k+LD+l+ +G++ g ++ i +   +Gk+ l+ ++a +
  EEA20564.1 104 ITTGSKQLDTLLaGGIETGSITEIFGEFRTGKSQLCHTLAVT 145
                 78999****8762689*******************9998865 PP

  == domain 2  score: 14.3 bits;  conditional E-value: 8.8e-06
                 HHHHHHHHHHHHTTEEEEEEEEGGGTBTS.CS....SSCCCHHHHHHHHHHHHHHHHCTSXEEEEEEXSGGG CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      DnaB_C 116 eirskarrlkkekglgliviDyLqlmegs.ee....kenreqevseisrsLkalakelnvpvialsqLsrav 182
                 ++ ++a ++  e++ +l+++D    +  +  +     +nr++ +++  r+L+ la e+ + v++  q+  +v
  EEA20564.1 204 QLLNQASQMMCETRFSLLIVDSATALYRTdFNgrgeLSNRQTHLAKFLRTLQRLADEFGIAVVITNQVVSQV 275
                 566788888899999******98777633222344366***************************9998776 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.3   4.4e-05     0.099       4     127 ..     121     267 ..     119     270 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 4.4e-05
      AAA_22   4 tagilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelka...........erlsseellealeqalrarav 91 
                 t +i+ ++Ge  tGK+ l+ +l+ + +   +    + ++++++  +   +  l  ++++ +gl +++           + + + +ll++  q + +++ 
  EEA20564.1 121 TGSITEIFGEFRTGKSQLCHTLAVTCQLPFDMGGGEGKCLYIDTEGTFRPVRL-LAVAQRYGLVGEEvldnvayarayNSDHQLQLLNQASQMMCETRF 218
                 778999******************97544444447777788888777755555.578888888888888899999888555555566555555555555 PP

      AAA_22  92 ielliiDEaqhlr......s..........eealeeLrsllnlsrkgvqliL 127
                  +lli+D a  l       +          ++ l++L +l++  ++g+++++
  EEA20564.1 219 -SLLIVDSATALYrtdfngRgelsnrqthlAKFLRTLQRLAD--EFGIAVVI 267
                 .6*********9877665515666788889999999999999..99999886 PP

>> PAXNEB  PAXNEB protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.1   0.00015      0.33      19      40 ..     104     125 ..      92     134 .. 0.88
   2 ?    0.9   0.0     0.086   1.9e+02     227     255 ..     240     268 ..     207     272 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00015
      PAXNEB  19 tStGtpsLDklLgGGLplGsil 40 
                 + tG+++LD+lL+GG+  Gsi 
  EEA20564.1 104 ITTGSKQLDTLLAGGIETGSIT 125
                 67*****************997 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.086
      PAXNEB 227 eeskpedllkFLhsLrallrssnlvalit 255
                  ++++++l kFL++L+ l+ +  + ++it
  EEA20564.1 240 LSNRQTHLAKFLRTLQRLADEFGIAVVIT 268
                 578999************99888888887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (349 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       424  (0.0236488); expected 358.6 (0.02)
Passed bias filter:                      406  (0.0226449); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.50u 0.24s 00:00:00.74 Elapsed: 00:00:00.40
# Mc/sec: 2628.46
//
Query:       EEA20565.1  [L=1322]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.2e-149  499.5   2.9   1.6e-149  499.0   2.9    1.2  1  Nup160    Nucleoporin Nup120/160


Domain annotation for each model (and alignments):
>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  499.0   2.9    9e-154  1.6e-149       1     536 [.      23     583 ..      23     584 .. 0.96

  Alignments for each domain:
  == domain 1  score: 499.0 bits;  conditional E-value: 9e-154
                 EE---STT-------------H........HHHHHHHHHHTTCEESSEEEEESSSSEEEEEE.EETTEEE..EEE---S...SSS--EEEEEE-SS-SE CS
      Nup160   1 itvptegssssqdstkasrtae........dEeafgarvaatagvvyfrksnsynrfilWrvltdgktLe..lvelslk...ssllnnnlrldFpssll 86 
                 i++pt+++ +++ +++ s+ +         d e f +r++at+g+vyfr+++ y+r++lWrv++d+++Le    ++s++   ++++n++lrldF+++++
  EEA20565.1  23 IEIPTAENAQQRVRISLSSGTArdentpikDDEDFARRYLATQGSVYFRQRKIYPRTFLWRVVNDSTVLEiqSTDVSKSivdRHEANLTLRLDFQEAII 121
                 6778888888888877766555677888999999************************************999999999999***************** PP

                 SSSESEEEEESSSEEEEEEEESSS-EEEEEEEHHHHHSTT----S..TSBEEB-SSGT.TTS-EEEEEE-SSSEEEEEETTS-EEEEEE..ETTEEEEE CS
      Nup160  87 pscvsftdsesgdvlivivtttsvhlyvlrlssdffrsskailndldewckidspsslstsskpgrlaavssnellvsladggllklkr..dedggawk 183
                 p +v+++d e++++l v+v+tts  l++++l+++ffr+ ++i++++++wck+  ps+l t+  p+rl+a s+ el+++l++g+ll+l+r  ++dg++w+
  EEA20565.1 122 PCGVALADAEDHEALNVFVLTTSRRLHTITLRPEFFRRVSSIDENIQDWCKSFIPSPL-TFTNPHRLHACSTTELFIALDSGALLRLTRraGDDGSHWS 219
                 **********************************************************.********************************99****** PP

                 EEEE-------B--TTTT.TSS--SS---TT-ECEEEEET......TTTEEEEEETT-EEEEEETTTTEEEEEEE--..-SSSTTS--SSEESEEESSS CS
      Nup160 184 esvfepksfllslsgllglladpsrrksgasvalsldvavavvei.gqtylfalsrdgkLrvWnlltgkclatidll.rdeeaqdessskstldpaess 280
                 + +f++k+++ sl+g++++++   + + g+s  l+  + ++++++ +qty+fa++++++L+vWnl+t+k++ t+dll +++ +q+ +s +  l+pa+s+
  EEA20565.1 220 QITFDEKTWGASLRGYVPWSGLQRVAYDGRS--LDPMTPNDIATTsDQTYVFAVCLNHTLKVWNLATNKLVGTKDLLdQPLSKQQPESTAYFLNPADSV 316
                 *******************************..8888888888888*******************************96666666666666******** PP

                 SEEEE................E--GGG-EEEEEEEEEEE-...SSSEEEEES-S------S-TT..--EEEEEEEEE-T..TEEEEEEEEEETTEEEEE CS
      Nup160 281 lirvs......dggqsylvvtyspssggefkvwkvkkedtsvslglvdlfleqtivpadpdssn..vweLrDfaltsse..kgfelwalwknnegsvlk 369
                 ++rv+      dgg++y+v ty p + g+fk+w+vk  +t + l ++dlf+++  +p dpds++  +w+++Df++ + e   ++elw+lw+nn  ++l+
  EEA20565.1 317 FLRVFnaeralDGGYRYYVATYTPHEMGQFKFWAVKGGLT-TPLTIEDLFPQAVFRPLDPDSTGnmFWTVADFQIRPMEegTRMELWVLWRNNGLYQLY 414
                 ****************************************.89********88666*******9*********************************** PP

                 EEEEE-SS-SS-.EEEEEE--------TTTTTS--SSGGG-SSHHHHHHHHH--.-HHHHHHHHHHHTTSS--ST.HHHTS-HHHHHHHHHHHHHTTS. CS
      Nup160 370 vlkinfesdeadtdddWssvsaseritdketlgdeedveeatkeyldrilepGrFsnavletALsifrrnlssss.svkslssaelkeevcsavesei. 466
                 +l++nfes e+d++ +W+s++ + r  ++ +  + +dv+++t+++  ++++pGr++ ++letAL  ++++l++    +  ++s  l+e++cs++++ + 
  EEA20565.1 415 TLHFNFESLEQDWSSNWVSTAWDSRRNEPAPALVVSDVVDPTEKWVEYFFHPGRYTVETLETALVAYQEALKPRAsATFLKRSVPLQERLCSTITASVs 513
                 ************************************************************************9887888999***************** PP

                 -B-SSSSSB-HHHHHHHHHHHHHHHHHHHHHTSSSSG-EEEEEEBTTTTBEEEEETTEEEEEE---HHHH CS
      Nup160 467 lndvseggadyeeyreaskreWerFyrlceeldkaaseplsLsldpqadvpwlirrdslslirpcselEv 536
                 l++++e+++dy +yr++++ +W++F++ +ee + ++ ep+sL++d ++d+pw+++ d+++lir+cs +E 
  EEA20565.1 514 LRKYAEDDMDYAKYRTDTDHKWRQFWQVVEEVHNRRLEPISLAYDTYSDMPWVVTTDACALIRECSATEL 583
                 ******************************************************************9996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1322 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       551  (0.0307323); expected 358.6 (0.02)
Passed bias filter:                      488  (0.0272185); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.81u 0.30s 00:00:01.11 Elapsed: 00:00:00.44
# Mc/sec: 9023.66
//
Query:       EEA20566.1  [L=572]
Description: MFS multidrug transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-33  115.6  50.6    2.9e-30  105.4  33.6    2.0  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.078   12.3   2.3       0.21   10.9   2.3    1.8  1  TMEM43    Transmembrane protein 43
        0.1   13.0   4.3       0.23   11.9   0.2    3.3  3  DUF2583   Protein of unknown function (DUF2583)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  105.4  33.6   4.8e-34   2.9e-30       3     316 ..     137     479 ..     135     481 .. 0.81
   2 !   19.8  20.6   5.2e-08   0.00031      63     174 ..     440     555 ..     437     570 .. 0.84

  Alignments for each domain:
  == domain 1  score: 105.4 bits;  conditional E-value: 4.8e-34
       MFS_1   3 laaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.sslwlllvlrvlqGlgag 100
                 l+++ s+la++i++p l   +++d+g+s+ +  l lt+  lg++++ l++++ls+ +Gr+  +l+ ++l +++ ++++ +   + ++l+ r+++G++++
  EEA20566.1 137 LTTMGSTLASAIYTPGLA-QISSDFGASKEVCLLGLTFLLLGFGFGPLLWAPLSELYGRKAAVLTPYFLAGIF-AFGTATaKDIQTVLITRFFTGFFGS 233
                 6889999***********.8***********99999*************************999999888888.44442326666************** PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllgglla.sslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 a +++ + ++ d++++++rg ai  +++++  G+ lgpl+gg ++ s+lgWr++ yi +i +++ + l +++l e++p+   + +++++          
  EEA20566.1 234 APVTNTGGVLGDIWSPQQRGAAIVGYALAVVGGPTLGPLIGGSISqSYLGWRWTQYITGIYMMFILTLDVIYLDESYPPVLLVYKARRLrhetgnwalh 332
                 ****************************************************************999999***99999999999999977777766655 PP

       MFS_1 189 ....kgtgpaplvp.......awkallkdpvlw...illialllfffgfsglltllply...lqevlglsglllaglllallalvgailallagrlsdr 270
                     +                a k+l ++  l+   i+++++l+++f++ +l+  l  +   + e +g++    +g+l+ ll+lvg+ ++  +  l +r
  EEA20566.1 333 akheE--------WdvtikemANKYLIRPFALLstpICFAIALYASFVYGILYLNLAAFpieFIEERGWG--PVVGGLPFLLMLVGILMGAGVNLLNQR 421
                 54441........03333343345555544444666799999999999999777666655558*******..455556666666666665555555555 PP

       MFS_1 271 .....lgr.......rrrlllallllllaalglallavtssavllllvlvliGfglgf 316
                      +++       + rl  ++++ +++a g++++a+tss+ +++++ ++  +++g+
  EEA20566.1 422 fyisrFKKnnnrpvpEARLPPMMIGSIAFASGMFIFAWTSSKRIHWIGPIIGAVCMGL 479
                 554444445555555*******************************977774446664 PP

  == domain 2  score: 19.8 bits;  conditional E-value: 5.2e-08
       MFS_1  63 r.vlllglllfalglllllfass...lw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyi 156
                    +++g ++fa+g+++++++ss   +w   +++ v +Glg  ++f a++ +++d fp    ++ai+  +   s+ a+  pl++g+++++lg  ++   
  EEA20566.1 440 LpPMMIGSIAFASGMFIFAWTSSkriHWiGPIIGAVCMGLGFFTIFQAAINYLVDTFPL-TAASAIAANTCLRSIFAAAFPLFAGAMYHNLGIDWAAST 537
                 4489**********777778533556676899999************************.************************************999 PP

       MFS_1 157 laivsllafvlfllllpe 174
                 l+++++ ++ + +l+++ 
  EEA20566.1 538 LGFIAVALIPIPFLFYVF 555
                 999999998865566543 PP

>> TMEM43  Transmembrane protein 43
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   2.3   3.5e-05      0.21     174     225 ..     454     508 ..     445     543 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 3.5e-05
      TMEM43 174 mfakeksenklltwllRllGfllmflgllllls.plsvlvslipll..gelvglg 225
                 mf  + +++k++ w+  ++G + m lg++++++  +++lv+ +pl   + +++ +
  EEA20566.1 454 MFIFAWTSSKRIHWIGPIIGAVCMGLGFFTIFQaAINYLVDTFPLTaaSAIAANT 508
                 66666778999****************998876369*********5332222222 PP

>> DUF2583  Protein of unknown function (DUF2583)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.1      0.23   1.4e+03       3      57 ..     251     305 ..     250     308 .. 0.84
   2 ?   -0.9   0.0      0.38   2.3e+03      20      34 ..     408     422 ..     394     458 .. 0.59
   3 ?   11.9   0.2   3.8e-05      0.23       8      61 ..     471     524 ..     463     528 .. 0.89

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.23
     DUF2583   3 rkkalllGnvlmglGlllmvaslaysvlnqlpelelpellaeaallgifiGallW 57 
                 ++ a+++G  l ++G  ++   ++ s+ +      ++++++ + ++ i+   +++
  EEA20566.1 251 QRGAAIVGYALAVVGGPTLGPLIGGSISQSYLGWRWTQYITGIYMMFILTLDVIY 305
                 5678999999999999999999999999999999999999999999887666655 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.38
     DUF2583  20 lmvaslaysvlnqlp 34 
                  ++++ ++++lnq +
  EEA20566.1 408 GILMGAGVNLLNQRF 422
                 223333344444333 PP

  == domain 3  score: 11.9 bits;  conditional E-value: 3.8e-05
     DUF2583   8 llGnvlmglGlllmvaslaysvlnqlpelelpellaeaallgifiGallWlaGa 61 
                 ++G v mglG+++++++    ++  +p    + + a++ l +if  a+  +aGa
  EEA20566.1 471 IIGAVCMGLGFFTIFQAAINYLVDTFPLTAASAIAANTCLRSIFAAAFPLFAGA 524
                 79************998777788889999999999************9999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (572 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       594  (0.0331307); expected 358.6 (0.02)
Passed bias filter:                      350  (0.0195214); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.27s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 3780.56
//
Query:       EEA20567.1  [L=698]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   6.9e-141  470.2   0.0   8.5e-141  469.9   0.0    1.1  1  DUF3808   Protein of unknown function (DUF3808)


Domain annotation for each model (and alignments):
>> DUF3808  Protein of unknown function (DUF3808)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  469.9   0.0  4.7e-145  8.5e-141       3     477 .]      30     574 ..      28     574 .. 0.94

  Alignments for each domain:
  == domain 1  score: 469.9 bits;  conditional E-value: 4.7e-145
     DUF3808   3 aldlvLndkfeeaeellkeaskeSslhalgrgviafleAvltfepekmkkAsealkeaeklceksrkkaqkneskqnl.ssdslyepgleaevcyaeal 100
                 +++l+L+d++++ae+ l+  +++Ss+h+ g+gv+ fl+A l+fe++ m++A+e+l +ae+ +++++++ +++ s + + +s ++y+ g+e+++c a+a+
  EEA20567.1  30 PATLILDDNVDGAENGLS--KGDSSFHKTGKGVVGFLRALLGFEQDIMREAAERLSDAETSAYNDQQRVTHTASTPDAfRS-QIYDVGTEYALCHAMAQ 125
                 5789*************7..899**************************************************99999666.9**************** PP

     DUF3808 101 LlkAlLtflseslvefiKgglklRkaYqiykeilkeikklekkkrskt................................................... 148
                 ++ A++++l+esl+e++Kg++k+RkaY++++ i  +++ + ++ +s t                                                   
  EEA20567.1 126 IMTAVVGVLNESLTESLKGFYKMRKAYSTLDGIVRMEERYLQTLKSRTalaplitekppaspkrrpygahisksdqdlhkkiadlkladdephsvpasa 224
                 ****************************************999999999***********************************************999 PP

     DUF3808 149 ........eeeeesllseekn....sqaeideflesGvnlgfGilqlviSllPpailklLsvvGFsGdreeGLrlLweasksrnlraalallaLlfYyt 235
                              ++l ++++    + + id f+++G +l++G+l  ++S lPp +++lL +vGF+Gd+++GLr+Lw+asks++l +a+a l +l+Yy+
  EEA20567.1 225 rssesstpL---GESLTHDPElvdlFSHPIDAFIHTGASLCLGMLLAMLSTLPPTFSRLLAIVGFHGDKDRGLRMLWQASKSTTLIGAVASLGILGYYN 320
                 998885332...333555555777999************************************************************************ PP

     DUF3808 236 gvvqvldi......ddg...lkapleeleelLlksrkrfPksalwllfearieslkgnldeAlelleeiieesqselkqvkhlclfelaltlvylheyk 325
                 g+v++ldi      +d+   +++p ++l+ lL  +r ++P+s+lwll+ear++s + +++ A+++l+   ++++s+lkqv+ l  fe++l+ ++lh+y+
  EEA20567.1 321 GFVRLLDIipdaikEDElgiEGYPADRLKTLLNTMRTQYPNSQLWLLEEARMKSGNRDVEGAVDILK---NSKKSPLKQVEGLQAFEKSLNSMFLHNYE 416
                 ********98655435568899*********************************************...578************************** PP

     DUF3808 326 eaaesfleLlklskwSkalYtYlaaacllelgre......ekkaeakekaeelfkevpkllqkkag..kslplekFilrKverfkarkkekkselldav 416
                 ++a+ fle+++l++wS alY+Y+a++ +  l+r       +++++++eka+e ++++p+ ++kk+   ++lp+e+F+ rK+++++ar+k  k++l+dav
  EEA20567.1 417 DCAKFFLECVDLNSWSPALYYYIAGSAYVILYRRtsdtdpAAAETYAEKATECIRKAPTVAGKKRLmaRQLPFEVFVTRKIAKWEARAKGLKVDLIDAV 515
                 **********************************9***998999999****************99999*******************999********* PP

     DUF3808 417 lvspvlEliYvwngfsrmskeeleeesvkkleekaanke.seeeeDdellkkLLkglvlrrl 477
                 +v+p++E+ ++wng+srm+ e le es+ +l +++  ++  + +eD++++ +LL++ +lr l
  EEA20567.1 516 GVDPIEEMNFLWNGYSRMGAEGLE-ESLHRLDQSE--EDvIRPDEDEKAITQLLRASILRAL 574
                 ************************.9****96663..34345899***************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (698 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       476  (0.0265492); expected 358.6 (0.02)
Passed bias filter:                      391  (0.0218082); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.67u 0.30s 00:00:00.97 Elapsed: 00:00:00.48
# Mc/sec: 4362.38
//
Query:       EEA20568.1  [L=87]
Description: 26 proteasome complex subunit Sem1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
      3e-23   81.6  17.3    3.9e-23   81.3  17.3    1.1  1  DSS1_SEM1  DSS1/SEM1 family


Domain annotation for each model (and alignments):
>> DSS1_SEM1  DSS1/SEM1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.3  17.3   2.2e-27   3.9e-23       2      60 .]      17      82 ..      16      82 .. 0.95

  Alignments for each domain:
  == domain 1  score: 81.3 bits;  conditional E-value: 2.2e-27
                HHHHHHHHHHTTSTTHHHHH----------.........---BESSTTTSCGGCHHHHHHHHHHHH CS
   DSS1_SEM1  2 ekkklklLeeDDEFEeFpvedwdeeeeeake.......ekklWednWDDddveddFskqLreELek 60
                +kk+ ++LeeDDEFE+Fpvedw +ee+e+ +       +++lWe++WDDdd ++dFskqL+eE++k
  EEA20568.1 17 QKKTPQVLEEDDEFEDFPVEDWPQEETEQGQgsnangtNTHLWEESWDDDDESEDFSKQLKEEMKK 82
                78999*****************999999888999**999*************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (87 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       959  (0.0534888); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.30s 00:00:00.69 Elapsed: 00:00:00.45
# Mc/sec: 578.31
//
Query:       EEA20569.1  [L=417]
Description: phosphoglycerate kinase PgkA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   5.4e-150  499.5   0.2   6.1e-150  499.4   0.2    1.0  1  PGK       Phosphoglycerate kinase
  ------ inclusion threshold ------
      0.063   13.3   1.0       0.26   11.3   0.0    2.5  3  PA        PA domain
       0.19   11.1   0.0        0.3   10.4   0.0    1.2  1  DUF3530   Protein of unknown function (DUF3530)


Domain annotation for each model (and alignments):
>> PGK  Phosphoglycerate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  499.4   0.2    1e-153  6.1e-150       1     378 []       9     406 ..       9     406 .. 0.95

  Alignments for each domain:
  == domain 1  score: 499.4 bits;  conditional E-value: 1e-153
                 GGGS--TT-EEEEEE-----EECTTEES--HHHHHHHHHHHHHHHTT-E.EEEEE--S--TTS-.GGG-SHHHHHHHHHHHTT-EEEESSTTSHHHHHH CS
         PGK   1 vkdldlkgkrvlvRvDfNvplkkegkitddtriraalpTikyllekgak.vvllsHlgrpkgek.eklslkpvaerLsellgkeVkfvedvvgeeveea 97 
                 ++d+d+k+krvl+RvDfNvpl+ e++it+++ri  alpTiky++++gak v+l+sHlgrp+g+  +k+sl+pv+ +L++llg++V f +d+vg+e+ee 
  EEA20569.1   9 ITDVDVKDKRVLIRVDFNVPLDAEKHITNNQRIVGALPTIKYAIDHGAKaVILMSHLGRPDGKVnPKYSLQPVVPELEKLLGRSVIFTKDCVGPETEEI 107
                 689**********************************************9**********99555********************************** PP

                 HHT-TTT-EEEES-GGGSTTTT.............TT-H....HHHHHHHHT-SEEEE--GGGTTS--TTTTHHHHCSEEEE-HHHHHHHHHHHHHHHS CS
         PGK  98 iaelkegevllLeNvrfykeEe.............knde....elakklasladvyVnDAFgtahrahaStvgiakvlsaaaGllmekElealskvlen 179
                 +++++ g+v+lLeN+rf++eEe             +  +    +++k+l++l+dvy+nDAFgtahrah+S+vg+    ++aaG+l++kEl++++++len
  EEA20569.1 108 VNKASGGQVILLENLRFHPEEEgsykdeqgnkvkaD--KakveKFRKELTALGDVYINDAFGTAHRAHSSMVGVDLP-QKAAGFLVKKELDYFAQALEN 203
                 *********************977777776666430..244447******************************955.56******************* PP

                 --SSEEEEEEES-HHHCHHHHHHHTTT-SEEEEETCHHHHHHHH.TT-B-TTSS--GGGHHHHHHHHHHHHHHT-EEE--SEEEEESSS.STTS..EEE CS
         PGK 180 perplvailGGakvsdkikvienLlekvdkliigGgmantFlka.qgleigkslveedklelakellekakkkgvkillpvDvvvakee.aeke.akvv 275
                 p+rp++ailGG+kvsdki++i+nLl kvd+lii+Ggma+tF k+ ++++ig+sl++e   +++ +++ekakk +vk++lpvD+v+a++  a++e ++++
  EEA20569.1 204 PKRPFLAILGGSKVSDKIQLIDNLLPKVDSLIITGGMAFTFKKTlENVKIGNSLFDEPGSKTVGDIIEKAKKYNVKVILPVDYVTASKFgADAEvGSAT 302
                 ********************************************9******************************************955666669999 PP

                 ECCG--TT-EEEEE-HHHHHHHHHHHCC-SEEEEES-SS-TTSGCCCHHHHHHHHHHHHHCH.TSEEEEESHHHHHHHHHTT-GGGSSEEESSSHHHHH CS
         PGK 276 eveaipedemalDigpktielfaeaikeaktvvwnGpmGvfeiekfakGTkaiakalaeatk.galsivGGgdsaaaveklgladkvshvStGGgAsLe 373
                 ++e ip+++ +lD+gpk++el+++ai+eakt++wnGp Gvfe e+fa+GTka ++a+ +a + ga++i+GGgd+a++++k++++dk+shvStGGgAsLe
  EEA20569.1 303 DAEGIPDGWLGLDVGPKSVELYKKAIAEAKTILWNGPPGVFELEPFASGTKATLDAAVAAAQsGAVVIIGGGDTATVAAKYKVEDKLSHVSTGGGASLE 401
                 ****************************************************99998777777************************************ PP

                 HHCTS CS
         PGK 374 lLegk 378
                 lLegk
  EEA20569.1 402 LLEGK 406
                 ****8 PP

>> PA  PA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   4.3e-05      0.26      21      57 ..      11      66 ..       3      85 .. 0.77
   2 ?   -2.8   0.0       1.1   6.8e+03      20      32 ..     203     225 ..     186     246 .. 0.69
   3 ?   -1.8   0.4      0.55   3.3e+03      25      32 ..     365     372 ..     349     399 .. 0.49

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 4.3e-05
          PA 21 gvdvkGkivLvqr.tf...................aeKarnAqaaGAagviivndge 57
                 vdvk k vL+ r +f                      ++ A ++GA++vi+ +  +
  EEA20569.1 11 DVDVKDKRVLI-RvDFnvpldaekhitnnqrivgaLPTIKYAIDHGAKAVILMSHLG 66
                569********.6677889999999999999**99999999************5443 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1.1
          PA  20 e..........gvdvkGkivLvq 32 
                 +          g++v+ ki L++
  EEA20569.1 203 NpkrpflailgGSKVSDKIQLID 225
                 34455666777788889998884 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 0.55
          PA  25 kGkivLvq 32 
                 +G +v++ 
  EEA20569.1 365 SGAVVIIG 372
                 24444442 PP

>> DUF3530  Protein of unknown function (DUF3530)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   5.1e-05       0.3     181     220 ..     353     389 ..     338     394 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 5.1e-05
     DUF3530 181 rarlqaaiaflnqrgaenivllghgtgAywaarylaekks 220
                  a l+aa+a +++     +v++g g++A  aa+y  e+k 
  EEA20569.1 353 KATLDAAVAAAQS---GAVVIIGGGDTATVAAKYKVEDKL 389
                 689**********...89****************877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (417 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       612  (0.0341346); expected 358.6 (0.02)
Passed bias filter:                      520  (0.0290033); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 2944.56
//
Query:       EEA20570.1  [L=262]
Description: integral membrane protein, Mpv17/PMP22 family, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.2e-19   70.2   0.2    1.2e-19   70.2   0.2    2.0  2  Mpv17_PMP22  Mpv17 / PMP22 family


Domain annotation for each model (and alignments):
>> Mpv17_PMP22  Mpv17 / PMP22 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.5      0.28     5e+03      28      42 ..     141     155 ..     133     159 .. 0.72
   2 !   70.2   0.2     7e-24   1.2e-19       2      62 .]     194     254 ..     193     254 .. 0.97

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 0.28
  Mpv17_PMP22  28 kvWppaqlinFyfvP 42 
                   +  p+q+  F+f++
   EEA20570.1 141 FFMAPIQFQWFRFLS 155
                  567788998898886 PP

  == domain 2  score: 70.2 bits;  conditional E-value: 7e-24
  Mpv17_PMP22   2 llegksleeikeelkekfwptlkanwkvWppaqlinFyfvPlkfRvlfvnvvslgWntyLS 62 
                  l eg  +   ++++++ ++ptlkan+ +Wp++q++nF++vP +f+++fv++v+++W++yLS
   EEA20570.1 194 LAEGGGRRALMNKFRDVYLPTLKANFILWPAVQVLNFRVVPIQFQIPFVSTVGIAWTAYLS 254
                  67999999****************************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (262 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       441  (0.024597); expected 358.6 (0.02)
Passed bias filter:                      339  (0.0189079); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.23s 00:00:00.67 Elapsed: 00:00:00.39
# Mc/sec: 2011.72
//
Query:       EEA20571.1  [L=577]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.5e-97  325.6   0.0    4.6e-97  325.2   0.0    1.1  1  Trs65     TRAPP trafficking subunit Trs65


Domain annotation for each model (and alignments):
>> Trs65  TRAPP trafficking subunit Trs65
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  325.2   0.0  2.6e-101   4.6e-97       1     315 [.     274     574 ..     274     575 .. 0.95

  Alignments for each domain:
  == domain 1  score: 325.2 bits;  conditional E-value: 2.6e-101
       Trs65   1 tpffdcevvlekidlslkggtvedlnqkdglslPlscvahDhltllYkLapeeldvklesnsssksssrelsIsieakvlvspkctpkismsWtTsldf 99 
                 tpf +c+vv++k ++ l++g+ve+++   +l+ P++++++D++tl+YkL pe+    +++  s+++ +++l+Is+e  ++++++c+p+i m+W+T++df
  EEA20571.1 274 TPFLSCDVVFDKAEVILSDGQVENISGVPELQPPITLRPRDDVTLIYKLIPEYG---PDAYFSTTALVSTLDISLEGVIKLTEECQPRIFMQWRTNVDF 369
                 799**********************999***********************999...899*************************************** PP

       Trs65 100 tlpvnpgfgtpsqsssliqrshrpsqlsisggsassslsspsvsrpdalpsleasasrtretsspdlgitltfsgpskkvkvGeefswkvfvvNrsske 198
                 ++p+np+fg psq    +qr++rp++ls+  g           s   ++ ++++s+ r+r++s+++ g+t++fsgp  +v++G++f+w++fvvNrs+ +
  EEA20571.1 370 SIPLNPTFGGPSQV---MQRNNRPTSLSMAAG----------QSGTPSTGAVNRSSYRERAHSFAQGGVTISFSGPV-NVEIGKPFQWDIFVVNRSRAP 454
                 ***********999...9**********6555..........23333455667777788999***************.********************* PP

       Trs65 199 rkLaLivipkrrrnevr..vsrpssssassk.nkkdeevadavldenvvhamqksskvdsaevvcLsnDiRvGpLapgacyevelrflalreGvlslea 294
                 rk+++++ip+r+r ++r  v+r+ssss ssk  kkdee a+av+den++hamqk+++ + ae+vcLs+D+R+GpL pg+c+++e+ +l+l++G l+lea
  EEA20571.1 455 RKFTMTAIPRRKRVDFRrhVTRTSSSSISSKkDKKDEELAEAVTDENIIHAMQKHAADQDAELVCLSTDLRLGPLLPGTCHSTEIILLPLATGALHLEA 553
                 *************9999999999999999987778999************************************************************* PP

       Trs65 295 vrvvDlgsqehvdirelpevv 315
                 vr+vD++++e++dir+lp++v
  EEA20571.1 554 VRLVDMNTNETIDIRDLPDIV 574
                 ********************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (577 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       424  (0.0236488); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 3655.43
//
Query:       EEA20572.1  [L=787]
Description: formin binding protein (FNB3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.6e-51  172.3  18.2    1.5e-13   50.7   0.3    7.0  6  FF              FF domain
      9e-19   67.3  14.4    3.1e-10   40.0   0.9    2.9  2  WW              WW domain
  ------ inclusion threshold ------
      0.022   15.0   6.2       0.54   10.6   2.1    2.7  2  Glyco_hyd_101C  Glycosyl hydrolase 101 beta sandwich domain


Domain annotation for each model (and alignments):
>> FF  FF domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.7   0.3   2.5e-17   1.5e-13       1      51 []     167     216 ..     167     216 .. 0.97
   2 !   46.1   1.1   6.8e-16   4.1e-12       2      51 .]     235     284 ..     234     284 .. 0.97
   3 !   19.7   0.2   1.2e-07   0.00073       2      51 .]     303     356 ..     302     356 .. 0.87
   4 !   47.5   0.0   2.5e-16   1.5e-12       3      50 ..     383     435 ..     381     436 .. 0.97
   5 ?    3.0   0.0      0.02   1.2e+02      10      34 ..     455     480 ..     452     482 .. 0.86
   6 !   12.4   0.1   2.3e-05      0.14      21      51 .]     538     568 ..     524     568 .. 0.91

  Alignments for each domain:
  == domain 1  score: 50.7 bits;  conditional E-value: 2.5e-17
                 CCHHHHHHHHHHCSSS-TTSSHHHHHHHCTTSCCCHHGTSHHHHHHHHHHH CS
          FF   1 kareaFkeLLkehkeitpkstWseikkilenDpRYlalldkseReelFedy 51 
                 +a++ F++LL+ ++ + p+++W++++++ ++Dp+Y+al+d+++R+++F+++
  EEA20572.1 167 EAESVFIKLLRRCN-VQPDWSWEQAMRATIKDPQYRALKDPKDRRAAFDKF 216
                 69999*********.*********************************997 PP

  == domain 2  score: 46.1 bits;  conditional E-value: 6.8e-16
                 CHHHHHHHHHHCSSS-TTSSHHHHHHHCTTSCCCHHGTSHHHHHHHHHHH CS
          FF   2 areaFkeLLkehkeitpkstWseikkilenDpRYlalldkseReelFedy 51 
                  r +F ++Lk+h ei+++s+W++i++i+e +  ++   d+ eR++lFe+y
  EEA20572.1 235 LRTDFYTMLKSHPEIKHYSRWKSIRPIIEGETIFRSTNDENERRQLFEEY 284
                 689**********************************************9 PP

  == domain 3  score: 19.7 bits;  conditional E-value: 1.2e-07
                 CHHHHHHHHHHCSSS-TTSSHHHHHH......HCTTSCCCHHGTSHHHHHHHHHHH CS
          FF   2 areaFkeLLkehkeitpkstWseikk......ilenDpRYlalldkseReelFedy 51 
                 a+++    Lk ++ ++p+ +Wse++       +++nD+ ++ l +ks+ +++Fe++
  EEA20572.1 303 AMDELVNILKALE-LEPYARWSEVQNalqaneRIQNDDKFKTL-SKSDILTAFENH 356
                 78899999****9.********6655555555***********.**********98 PP

  == domain 4  score: 47.5 bits;  conditional E-value: 2.5e-16
                 HHHHHHHHHHCS...SS-TTSSHHHHHHHCTTSCCCHHG..TSHHHHHHHHHH CS
          FF   3 reaFkeLLkehk...eitpkstWseikkilenDpRYlal..ldkseReelFed 50 
                 re + eLLke+    +i++  +W +i++++++DpRY a+  +++s++++lF+d
  EEA20572.1 383 REKYLELLKELRsqgKIKAGAKWMQIHPLIQDDPRYVAMlgQSGSSPLDLFWD 435
                 899*************************************************9 PP

  == domain 5  score: 3.0 bits;  conditional E-value: 0.02
                 HHHCS.SS-TTSSHHHHHHHCTTSCC CS
          FF  10 Lkehk.eitpkstWseikkilenDpR 34 
                 L+++  eit k+t++e+ ++   D R
  EEA20572.1 455 LDDKRyEITTKTTYEEFASVMATDRR 480
                 7788889**********999888877 PP

  == domain 6  score: 12.4 bits;  conditional E-value: 2.3e-05
                 SHHHHHHHCTTSCCCHHGTSHHHHHHHHHHH CS
          FF  21 tWseikkilenDpRYlalldkseReelFedy 51 
                 tW++++++ e+ ++Y+al+++  R+++Fe++
  EEA20572.1 538 TWEQVQPRVEKFEEYTALESEDLRLSAFEKF 568
                 9****************************97 PP

>> WW  WW domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.0   0.9   5.1e-14   3.1e-10       5      31 .]      14      39 ..      11      39 .. 0.97
   2 !   31.0   6.7   3.2e-11   1.9e-07       4      31 .]      54      80 ..      52      80 .. 0.96

  Alignments for each domain:
  == domain 1  score: 40.0 bits;  conditional E-value: 5.1e-14
                EEEEE-TTTT-EEEEETTT--EESS-- CS
          WW  5 WeeqwdpdsGrvYYyNheTgetqWekP 31
                W+e++ +d GrvYYyN +T++tqWekP
  EEA20572.1 14 WQEARNAD-GRVYYYNVQTKVTQWEKP 39
                ********.*****************9 PP

  == domain 2  score: 31.0 bits;  conditional E-value: 3.2e-11
                TEEEEE-TTTT-EEEEETTT--EESS-- CS
          WW  4 GWeeqwdpdsGrvYYyNheTgetqWekP 31
                +W+e++ +  Gr+Y+yN++T++++We P
  EEA20572.1 54 PWKEYTAEG-GRKYWYNTQTKQSTWEMP 80
                8****9999.****************99 PP

>> Glyco_hyd_101C  Glycosyl hydrolase 101 beta sandwich domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.1    0.0032        19      77     100 ..      18      41 ..      10      50 .. 0.81
   2 ?   10.6   2.1     9e-05      0.54      68     113 ..      56      96 ..      43      98 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0032
                     -GGG-EEEEEESS-SEEEEE--HH CS
  Glyco_hyd_101C  77 kadeeklYhynpkggtstwkLpek 100
                     ++ + ++Y+yn +   ++w+ p +
      EEA20572.1  18 RNADGRVYYYNVQTKVTQWEKPAD 41 
                     44455**************98876 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 9e-05
                     -B-TTS-B--GGG-EEEEEESS-SEEEEE--HHHHT..S--EEEEEE CS
  Glyco_hyd_101C  68 nadatgkkekadeeklYhynpkggtstwkLpekwak.kssvklYkLt 113
                     +      + +a+  + Y+yn++  +stw++pe +++  ++ ++Y Lt
      EEA20572.1  56 K------EYTAEGGRKYWYNTQTKQSTWEMPEVYKTaLAQGSVYVLT 96 
                     4......456667788****************998614677888887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (787 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1587  (0.0885158); expected 358.6 (0.02)
Passed bias filter:                      458  (0.0255452); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.74u 0.31s 00:00:01.05 Elapsed: 00:00:00.46
# Mc/sec: 5195.88
//
Query:       EEA20573.1  [L=604]
Description: RNase L inhibitor of the ABC superfamily, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.4e-37  127.7   0.0    4.6e-17   62.8   0.0    2.4  2  ABC_tran         ABC transporter
      3e-14   52.6   5.5      3e-14   52.6   5.5    2.1  1  RLI              Possible Fer4-like domain in RNase L inhibit
    9.1e-14   52.0   5.5     0.0062   16.4   0.0    4.2  4  AAA_21           AAA domain, putative AbiEii toxin, Type IV T
    1.1e-12   47.8   2.1    0.00071   19.1   0.1    4.0  4  SMC_N            RecF/RecN/SMC N terminal domain
    1.7e-06   28.5   0.0      0.009   16.4   0.0    2.5  2  AAA_16           AAA ATPase domain
    3.7e-06   27.4   0.0      0.017   15.5   0.0    2.5  2  AAA              ATPase family associated with various cellul
    5.5e-06   26.7   0.0     0.0041   17.4   0.0    2.6  2  AAA_22           AAA domain
      1e-05   25.4   0.4       0.32   10.7   0.1    3.1  3  AAA_15           AAA ATPase domain
    2.5e-05   24.8   0.0       0.56   10.8   0.0    3.5  3  AAA_18           AAA domain
      4e-05   23.3   0.5       0.12   12.1   0.0    2.6  2  AAA_29           P-loop containing region of AAA domain
    7.3e-05   22.4   2.5    7.3e-05   22.4   2.5    2.7  3  Fer4             4Fe-4S binding domain
    0.00026   20.8   0.2      0.045   13.5   0.0    2.4  2  AAA_24           AAA domain
    0.00027   20.9   0.1       0.27   11.1   0.0    2.4  2  RsgA_GTPase      RsgA GTPase
     0.0004   20.7   0.6       0.51   10.6   0.0    2.7  2  AAA_28           AAA domain
    0.00042   20.3   0.0      0.077   12.9   0.0    2.4  2  Rad17            Rad17 P-loop domain
    0.00077   19.2   0.8        1.4    8.6   0.0    2.4  2  AAA_30           AAA domain
    0.00078   20.0   1.7       0.38   11.2   0.3    2.5  2  AAA_23           AAA domain
    0.00086   19.5   0.3          1    9.5   0.0    2.5  2  AAA_33           AAA domain
    0.00096   17.9   0.6     0.0065   15.2   0.0    2.1  2  AAA_13           AAA domain
     0.0014   19.0   0.7       0.92    9.9   0.0    2.9  2  RNA_helicase     RNA helicase
     0.0022   18.1  11.3     0.0045   17.1  11.3    1.5  1  Fer4_21          4Fe-4S dicluster domain
     0.0022   17.5   0.1       0.27   10.7   0.0    2.3  2  AAA_7            P-loop containing dynein motor region
     0.0026   17.8   0.2      0.038   14.0   0.0    2.4  2  TsaE             Threonylcarbamoyl adenosine biosynthesis pro
     0.0034   17.4  12.3     0.0077   16.3   2.2    2.5  2  Fer4_6           4Fe-4S binding domain
     0.0078   15.4   0.0        2.1    7.5   0.0    2.6  2  NB-ARC           NB-ARC domain
  ------ inclusion threshold ------
      0.011   15.7   1.4        2.1    8.3   0.0    3.1  3  AAA_5            AAA domain (dynein-related subfamily)
      0.014   15.3   2.1       0.68    9.8   0.1    2.8  3  NACHT            NACHT domain
      0.017   15.1   0.4        3.1    7.8   0.1    3.3  2  AAA_14           AAA domain
      0.018   14.8   0.0        4.7    6.9   0.0    2.4  2  VirE             Virulence-associated protein E
      0.019   14.6   0.5        2.4    7.7   0.0    2.5  2  AAA_25           AAA domain
      0.021   14.9  15.6      0.022   14.9   1.6    2.4  2  Fer4_10          4Fe-4S dicluster domain
      0.026   14.2   3.6       0.44   10.1   0.1    2.3  2  SRP54            SRP54-type protein, GTPase domain
      0.029   14.0   0.7        6.5    6.4   0.0    2.8  2  Thymidylate_kin  Thymidylate kinase
      0.036   13.2   0.1        7.5    5.6   0.0    2.3  2  DUF815           Protein of unknown function (DUF815)
      0.051   13.7   0.7         14    5.8   0.0    2.6  2  MMR_HSR1         50S ribosome-binding GTPase
      0.058   12.2   0.4        0.1   11.4   0.0    1.5  2  DLIC             Dynein light intermediate chain (DLIC)
      0.059   13.1   2.3       0.12   12.1   0.1    2.5  2  PduV-EutP        Ethanolamine utilisation - propanediol utili
      0.071   13.3  11.7       0.15   12.3  11.7    1.6  1  Fer4_9           4Fe-4S dicluster domain
      0.078   13.9   0.3      0.078   13.9   0.3    2.7  2  Fer4_16          4Fe-4S double cluster binding domain
       0.09   12.1   1.6       0.15   11.4   0.1    1.9  2  ATPase           KaiC
       0.11   11.8   0.0        7.2    5.7   0.0    2.2  2  KAP_NTPase       KAP family P-loop domain
       0.12   12.1   0.7         13    5.5   0.0    2.8  3  MukB             MukB N-terminal
       0.28   11.7   6.7       0.29   11.6   0.2    2.4  2  Fer4_8           4Fe-4S dicluster domain
       0.38   10.5   1.5          5    6.9   0.1    2.5  2  CLP1_P           mRNA cleavage and polyadenylation factor CLP
        0.6   10.8  12.7      0.069   13.7   1.6    2.2  3  Fer4_7           4Fe-4S dicluster domain
        1.8    8.8   9.9       0.25   11.5   1.2    2.6  2  Fer4_2           4Fe-4S binding domain
          2    8.3   3.6         11    6.0   0.2    2.8  3  NTPase_1         NTPase
        5.8    7.5  10.4       0.21   12.2   0.8    2.5  2  Fer4_17          4Fe-4S dicluster domain


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.8   0.0   1.2e-19   4.6e-17      10     136 ..     102     247 ..     100     248 .. 0.74
   2 !   62.5   0.0   1.6e-19   5.9e-17       6     137 .]     370     493 ..     365     493 .. 0.87

  Alignments for each domain:
  == domain 1  score: 62.8 bits;  conditional E-value: 1.2e-19
                 TTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH............................H CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............................x RF
    ABC_tran  10 egekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren............................e 80 
                 +g+++++vG nG+GKSt lk+l+g+lkp+ G+   d  d++e+ + +  +e++ ++ +  l ++l+                                 
  EEA20573.1 102 PGQVLGLVGANGTGKSTALKILSGKLKPNLGRY-DDPPDWQEILKYFRGSELQNYFTK-VLEDNLK---AvvkpqyvdqipravkgpvkevgpliearS 195
                 89******************************8.224444443333333333333333.2222222...022234555556666667788899997765 PP

                 HHTCHHHHHHHSTTGGTTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  81 sdeeiekalsklglkelkdtvvksspssLSgGqkqrvalarallkkpkllllDEpt 136
                 + ++++++++ l+lk+++++ +    + LSgG+ qr ala + +++++++++DEp+
  EEA20573.1 196 QMDNMDRIMDVLELKQVENRDI----NLLSGGELQRFALALVCVQQADVYMFDEPS 247
                 6666*****************9....*****************************7 PP

  == domain 2  score: 62.5 bits;  conditional E-value: 1.6e-19
                 EEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSB.HHHHHHHTCHHHHHHHSTTGGTTCBGES CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran   6 lklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpelt.vrenesdeeiekalsklglkelkdtvvk 103
                  k+  +e+v+++GenG+GK+t++k+lag +kp  G++ +   ++++++ +++ k  g++ q   +f++++ +      +  +++ + l+++++ d+ v 
  EEA20573.1 370 GKFTDSEIVVLMGENGTGKTTFCKMLAGAEKP-DGTVSIPRMNISMKPQKITPKFTGTVRQL--FFKRIKaAF--LNPQFQTDVYKPLRIDDFIDQEV- 462
                 578899************************98.8***9*99999999999999999999999..666663122..33334568889999999999999. PP

                 TTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran 104 sspssLSgGqkqrvalarallkkpkllllDEpta 137
                    ++LSgG+ qrva++ al   ++++l+DEp+a
  EEA20573.1 463 ---QNLSGGELQRVAIVLALGIPADIYLIDEPSA 493
                 ...*****************************75 PP

>> RLI  Possible Fer4-like domain in RNase L inhibitor, RLI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.6   5.5   7.9e-17     3e-14       1      35 []       6      37 ..       6      37 .. 0.96

  Alignments for each domain:
  == domain 1  score: 52.6 bits;  conditional E-value: 7.9e-17
                --EEEES---------TTHHHHHTTSEEEESS--S CS
         RLI  1 mrlAivdadqCdPKKCtgkkcarfcpvrlvrtgkk 35
                +r+Aiv+ d+C+PKKC++ +c+++cpv  vrtgk+
  EEA20573.1  6 TRIAIVNSDKCKPKKCRQ-ECKKSCPV--VRTGKL 37
                59****************.********..****95 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   1.6   3.1e-05     0.012       3      21 ..     107     125 ..     105     140 .. 0.87
   2 !   16.4   0.0   1.7e-05    0.0062     168     282 ..     160     266 ..     125     282 .. 0.68
   3 !   10.0   0.0    0.0015      0.55       1      49 [.     377     419 ..     377     426 .. 0.78
   4 !    9.0   0.0     0.003       1.1     214     279 ..     457     507 ..     419     522 .. 0.65

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 3.1e-05
      AAA_21   3 vliGpNgsGKSnLLdaldl 21 
                 +l+G+Ng+GKS+ L++l++
  EEA20573.1 107 GLVGANGTGKSTALKILSG 125
                 79***************74 PP

  == domain 2  score: 16.4 bits;  conditional E-value: 1.7e-05
      AAA_21 168 llnifadyfgfakekrllqrlvrslklveielsdlgegeeliasvderlrergvvflengdgqelparelSdGtkrllalltallralkkgsllliDEp 266
                 l ++ ++ ++++ + ++ +   +++k+v++ +++   ++++            +  le ++  +++++ lS G ++ +al++ + +++   +++ +DEp
  EEA20573.1 160 LEDNLKAVVKPQYVDQIPRAVKGPVKEVGPLIEARSQMDNMDR---------IMDVLELKQVENRDINLLSGGELQRFALALVCVQQA---DVYMFDEP 246
                 4444444444444444444444444444444444443333333.........8888899999************************99...9******* PP

      AAA_21 267 EngLHP....kllrrllell 282
                  + L+     ++ r++ ell
  EEA20573.1 247 SSYLDIrqrlAAARTIRELL 266
                 *****966655558888877 PP

  == domain 3  score: 10.0 bits;  conditional E-value: 0.0015
      AAA_21   1 lnvliGpNgsGKSnLLdaldllarldrdvegltdelsggggirkipsll 49 
                 + vl G Ng+GK+++ + l      ++  +++++++ ++ +i++ p ++
  EEA20573.1 377 IVVLMGENGTGKTTFCKML------AGAEKPDGTVSIPRMNISMKPQKI 419
                 679**************99......555778888777777777666655 PP

  == domain 4  score: 9.0 bits;  conditional E-value: 0.003
      AAA_21 214 erlrergvvflengdgqelparelSdGtkrllalltallralkkgsllliDEpEngLHPkll...rrll 279
                 + ++                + +lS G ++  a+++al   +   +++liDEp + L+ +     +r++
  EEA20573.1 457 FIDQ---------------EVQNLSGGELQRVAIVLALGIPA---DIYLIDEPSAYLDAEQRitaSRVI 507
                 3333...............47788999999999999999999...************995542343333 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.0     0.035        13      13      40 ..      92     119 ..      87     125 .. 0.76
   2 !   19.1   0.1   1.9e-06   0.00071     122     202 ..     205     282 ..     191     297 .. 0.78
   3 ?    4.8   0.1     0.043        16      23      41 ..     374     392 ..     363     400 .. 0.84
   4 !   15.2   0.0     3e-05     0.011     135     194 ..     463     521 ..     398     529 .. 0.72

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.035
                 EECEEEEEETTSSEEEEEESTTSSHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  13 yagktvilpfsksftaivGpNGSGKsnl 40 
                 ++ ++  +p   ++  +vG+NG GKs  
  EEA20573.1  92 FKLHRLPMPRPGQVLGLVGANGTGKSTA 119
                 55556666666778889*********75 PP

  == domain 2  score: 19.1 bits;  conditional E-value: 1.9e-06
                 HHHHHHHCTT-STTCS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTT.SEEEEE-SSHHHC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxx RF
       SMC_N 122 evsellesagiskelLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkekskn.aQfivislreeml 202
                 +v el + ++ +++lLSgGe +  alaL+     v++a +y++De  + LD +++ + a+ ++e       +iv+ ++  +l
  EEA20573.1 205 DVLELKQVENRDINLLSGGELQRFALALV----CVQQADVYMFDEPSSYLDIRQRLAAARTIRELLRPdDYVIVVEHDLSVL 282
                 445555555567889**********9999....678889************************9765426677777766655 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.043
                 TSSEEEEEESTTSSHHHHH CS
                 xxxxxxxxxxxxxxxxxxx RF
       SMC_N  23 sksftaivGpNGSGKsnll 41 
                 ++++ +++G+NG GK+ ++
  EEA20573.1 374 DSEIVVLMGENGTGKTTFC 392
                 5678899********9886 PP

  == domain 4  score: 15.2 bits;  conditional E-value: 3e-05
                 TCS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHH...HHCTTSEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxx RF
       SMC_N 135 elLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellk...eksknaQfiv 194
                 ++LSgGe + va+ L + i    pa +yl+De  a LD++++   ++++k    ++k++ fiv
  EEA20573.1 463 QNLSGGELQRVAIVLALGI----PADIYLIDEPSAYLDAEQRITASRVIKrfiMNTKKTAFIV 521
                 39*****877766666655....999***************9998888883334555666665 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.9   0.0    0.0025      0.92      16      63 ..      94     137 ..      91     277 .. 0.74
   2 !   16.4   0.0   2.4e-05     0.009      23     107 ..     374     491 ..     362     558 .. 0.63

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.0025
      AAA_16  16 lervrsgrp.elvllsGesGvGKsslvrellralekdggiflrgkcdql 63 
                 l+r+ ++rp +++ l+G+ G+GKs+ ++ l   l+ +      g++d+ 
  EEA20573.1  94 LHRLPMPRPgQVLGLVGANGTGKSTALKILSGKLKPN-----LGRYDDP 137
                 78889999989999************99888888777.....4454444 PP

  == domain 2  score: 16.4 bits;  conditional E-value: 2.4e-05
      AAA_16  23 rpelvllsGesGvGKsslvrellralekdggif......lrgkcdqlesaipy.salaqalareellrqlldeaesaeleawrekleeala........ 106
                 ++e+v+l Ge G+GK++  ++l+ a + d g +      ++ k ++    +p     +++l++ + +++   +++ +   + + ++++ +         
  EEA20573.1 374 DSEIVVLMGENGTGKTTFCKMLAGAEKPD-GTVsiprmnISMKPQKI---TPKfTGTVRQLFF-KRIKAAFLNPQFQTDVYKPLRIDDFIDqevqnlsg 467
                 349********************666655.44444555566666665...4442335555534.55555555544444444444333333352224444 PP

      AAA_16 107 .......................a 107
                                        +
  EEA20573.1 468 gelqrvaivlalgipadiylideP 491
                 545455555555555555555554 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.0    0.0039       1.4       3      51 ..     108     169 ..     106     216 .. 0.77
   2 !   15.5   0.0   4.6e-05     0.017       1      44 [.     378     429 ..     378     448 .. 0.61

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.0039
                 EESSTTSSHHHHHHHHHHHHTHE.............EEEEETTTCSSSSTTHHHHHHHHHHH CS
         AAA   3 lyGppGtGKTllakavakelgve.............fleisgsellskyvgesekkirelfk 51 
                 l+G  GtGK+++ k +  +l+ +             +  + gsel + + +  e+++++++k
  EEA20573.1 108 LVGANGTGKSTALKILSGKLKPNlgryddppdwqeiLKYFRGSELQNYFTKVLEDNLKAVVK 169
                 89*****************9755444455556666556667777776666666666666655 PP

  == domain 2  score: 15.5 bits;  conditional E-value: 4.6e-05
                 EEEESSTTSSHHHHHHHHHHHHT....HE....EEEEETTTCSSSSTTHHHH CS
         AAA   1 vllyGppGtGKTllakavakelg....ve....fleisgsellskyvgesek 44 
                 v+l+G  GtGKT+++k +a   +    v+     ++++  +++ k+ g   +
  EEA20573.1 378 VVLMGENGTGKTTFCKMLAGAEKpdgtVSiprmNISMKPQKITPKFTGTVRQ 429
                 689****************995433333311112333444444444444433 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.0     0.025       9.4       6      29 ..     104     127 ..     101     145 .. 0.84
   2 !   17.4   0.0   1.1e-05    0.0041       6      81 ..     376     461 ..     373     521 .. 0.69

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.025
      AAA_22   6 gilvvtGesGtGKTtllrrlleql 29 
                 ++l ++G  GtGK+t l+ l  +l
  EEA20573.1 104 QVLGLVGANGTGKSTALKILSGKL 127
                 566799**********99876665 PP

  == domain 2  score: 17.4 bits;  conditional E-value: 1.1e-05
      AAA_22   6 gilvvtGesGtGKTtllrrlleqldeeakaee......erpevv....fvtlpsstsskdl.lrellralglelka....erlsseell.ea 81 
                  i+v++Ge GtGKTt +++l+   + +           ++        ++t++  ++ ++l ++++  a+ +++      ++l+ ++++ + 
  EEA20573.1 376 EIVVLMGENGTGKTTFCKMLAGAEKPD----GtvsiprMNI--SmkpqKITPKFTGTVRQLfFKRIKAAFLNPQFQtdvyKPLRIDDFIdQE 461
                 589*****************9997533....2334344333..1346677777777777776888888877777776776666666666333 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.5   0.0   0.00098      0.37      28      44 ..     108     124 ..     100     174 .. 0.82
   2 !   10.7   0.1   0.00085      0.32      23      43 ..     375     395 ..     361     456 .. 0.85
   3 ?   -0.2   0.0       1.7   6.3e+02     324     356 ..     483     515 ..     479     528 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00098
      AAA_15  28 liGkNnsGKSsileald 44 
                 l+G+N++GKS++l++l 
  EEA20573.1 108 LVGANGTGKSTALKILS 124
                 8**************94 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 0.00085
      AAA_15  23 eeltvliGkNnsGKSsileal 43 
                 +e+ vl G+N++GK+++ ++l
  EEA20573.1 375 SEIVVLMGENGTGKTTFCKML 395
                 2399*************9998 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 1.7
      AAA_15 324 nvilliEEPEahLHpqaqkvlikllkelandnk 356
                  +i+li+EP a+L  ++     + +k+ + ++k
  EEA20573.1 483 ADIYLIDEPSAYLDAEQRITASRVIKRFIMNTK 515
                 68**********977777666666666665555 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.8   0.0    0.0015      0.56       3      54 ..     108     154 ..     106     207 .. 0.68
   2 ?   -0.5   0.0       4.5   1.7e+03      71      99 ..     337     365 ..     239     371 .. 0.72
   3 !    9.9   0.0    0.0028       1.1       1      19 [.     378     396 ..     378     510 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.0015
      AAA_18   3 ltGtpGvGKttlakeLskrl.gf.........gvnlrdvakenglllevdpealdeskrlde 54 
                 l G+ G+GK+t  k Ls +l  +         ++++                ++ +  +l+ 
  EEA20573.1 108 LVGANGTGKSTALKILSGKLkPNlgryddppdWQEIL---------------KYFRGSELQN 154
                 89**************999732234444444422222...............3333333333 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 4.5
      AAA_18  71 leegknlvidghlaeleseaakdikkvvL 99 
                  e g+  ++d  +a +++ + k ++ ++L
  EEA20573.1 337 AEAGDEFLVDKGRAFHYPKMEKTMGNFHL 365
                 35677777777777777777666665665 PP

  == domain 3  score: 9.9 bits;  conditional E-value: 0.0028
      AAA_18   1 IlltGtpGvGKttlakeLs 19 
                 ++l+G  G+GKtt++k L+
  EEA20573.1 378 VVLMGENGTGKTTFCKMLA 396
                 6899************995 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.1   0.0   0.00032      0.12      12      39 ..      92     120 ..      87     129 .. 0.87
   2 !    8.5   0.1    0.0045       1.7      19      38 ..     372     391 ..     361     395 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00032
      AAA_29  12 fdghtieidlkg.atlltGpsGsGKSTll 39 
                 f+ h++++ + g +  l+G++G+GKST l
  EEA20573.1  92 FKLHRLPMPRPGqVLGLVGANGTGKSTAL 120
                 7778999999998888***********76 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0045
      AAA_29  19 idlkgatlltGpsGsGKSTl 38 
                 ++ +++++l+G++G+GK+T+
  EEA20573.1 372 FTDSEIVVLMGENGTGKTTF 391
                 55566899***********7 PP

>> Fer4  4Fe-4S binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.1       7.9   2.9e+03       2       8 ..      10      16 ..       9      17 .. 0.85
   2 ?   -0.5   0.6       3.5   1.3e+03      13      20 ..      24      31 ..      23      32 .. 0.88
   3 !   22.4   2.5   1.9e-07   7.3e-05       3      23 ..      50      70 ..      48      71 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 7.9
                EEETTTS CS
        Fer4  2 videekC 8 
                +++ +kC
  EEA20573.1 10 IVNSDKC 16
                799**** PP

  == domain 2  score: -0.5 bits;  conditional E-value: 3.5
                HHHHHSTT CS
        Fer4 13 aCvevCPv 20
                +C + CPv
  EEA20573.1 24 ECKKSCPV 31
                69*****8 PP

  == domain 3  score: 22.4 bits;  conditional E-value: 1.9e-07
                EETTTSSS-THHHHHSTTTEE CS
        Fer4  3 ideekCigCGaCvevCPvgAI 23
                i e +CigCG+C + CP+gAI
  EEA20573.1 50 ISERLCIGCGICPKKCPFGAI 70
                78999***************9 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.0     0.054        20       4      22 ..     105     123 ..     103     143 .. 0.86
   2 !   13.5   0.0   0.00012     0.045       5      23 ..     378     398 ..     375     410 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.054
      AAA_24   4 kiliyGpsgiGKTtlakel 22 
                  + ++G +g+GK+t +k l
  EEA20573.1 105 VLGLVGANGTGKSTALKIL 123
                 57899*********99977 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 0.00012
      AAA_24   5 iliyGpsgiGKTtlakel..g 23 
                 ++++G++g+GKTt++k+l   
  EEA20573.1 378 VVLMGENGTGKTTFCKMLagA 398
                 79**************99652 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   0.0     0.012       4.3      89     125 ..      93     129 ..      71     136 .. 0.75
   2 !   11.1   0.0   0.00073      0.27      98     123 ..     374     399 ..     355     420 .. 0.87

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.012
                  THHHHHHHCTTSEEEEECSTTSSHHHHHHHHCTT--- CS
  RsgA_GTPase  89 gleelkellkdktsvlvGqSGvGKStLinallpelel 125
                  +l++l     +++  lvG  G GKSt ++ l ++l+ 
   EEA20573.1  93 KLHRLPMPRPGQVLGLVGANGTGKSTALKILSGKLKP 129
                  555555556678999**************99998765 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00073
                  TTSEEEEECSTTSSHHHHHHHHCTT- CS
  RsgA_GTPase  98 kdktsvlvGqSGvGKStLinallpel 123
                  +++++vl+G+ G GK+t+ ++l++ +
   EEA20573.1 374 DSEIVVLMGENGTGKTTFCKMLAGAE 399
                  4599******************9864 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   0.2     0.011       4.2       4      20 ..     108     124 ..     106     135 .. 0.87
   2 !   10.6   0.0    0.0014      0.51       2      29 ..     378     409 ..     377     433 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.011
      AAA_28   4 itGgestGKTtlleaLa 20 
                 ++G+ +tGK+t l+ L+
  EEA20573.1 108 LVGANGTGKSTALKILS 124
                 78************998 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.0014
      AAA_28   2 ivitGgestGKTtlleaLa.ar...gypvvpE 29 
                 +v++G  +tGKTt ++ La a+   g++ +p+
  EEA20573.1 378 VVLMGENGTGKTTFCKMLAgAEkpdGTVSIPR 409
                 89*****************5224667777766 PP

>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.9   0.0    0.0002     0.077      43      80 ..     101     138 ..      90     170 .. 0.84
   2 ?    4.9   0.0     0.057        21      44      82 ..     374     412 ..     350     492 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 0.0002
       Rad17  43 rkkriLLisGPsGCgkstvvkvLskelgiklrewlnpv 80 
                 r+ ++L + G  G gkst++k+Ls +l ++l  + +p 
  EEA20573.1 101 RPGQVLGLVGANGTGKSTALKILSGKLKPNLGRYDDPP 138
                 56789*******************99999887776665 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.057
       Rad17  44 kkriLLisGPsGCgkstvvkvLskelgiklrewlnpvsl 82 
                   +i+++ G  G gk+t  k+L+    ++    +  +++
  EEA20573.1 374 DSEIVVLMGENGTGKTTFCKMLAGAEKPDGTVSIPRMNI 412
                 446999****************97766665555555554 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.5   0.1    0.0041       1.5      19      39 ..     104     124 ..      99     133 .. 0.84
   2 !    8.6   0.0    0.0037       1.4      17      42 ..     375     399 ..     370     412 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.0041
      AAA_30  19 rvavltGpAGtGKttalkalr 39 
                 +v  l+G+ GtGK+talk l 
  EEA20573.1 104 QVLGLVGANGTGKSTALKILS 124
                 68889************9875 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.0037
      AAA_30  17 gdrvavltGpAGtGKttalkalreaw 42 
                 +  ++vl G  GtGKtt  k l+ a 
  EEA20573.1 375 S-EIVVLMGENGTGKTTFCKMLAGAE 399
                 3.399*************99988765 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.1     0.015       5.8      24      38 ..     108     122 ..     101     136 .. 0.89
   2 !   11.2   0.3     0.001      0.38      17      36 ..     372     392 ..     358     398 .. 0.78

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.015
      AAA_23  24 ItGpNGaGKTTildA 38 
                 ++G NG+GK+T l  
  EEA20573.1 108 LVGANGTGKSTALKI 122
                 79*********9875 PP

  == domain 2  score: 11.2 bits;  conditional E-value: 0.001
      AAA_23  17 F.skgltlItGpNGaGKTTil 36 
                 F ++ ++++ G+NG+GKTT+ 
  EEA20573.1 372 FtDSEIVVLMGENGTGKTTFC 392
                 3677899************85 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.9   0.2    0.0088       3.3       4      24 ..     108     128 ..     105     275 .. 0.85
   2 !    9.5   0.0    0.0027         1       2      25 ..     378     402 ..     377     453 .. 0.81

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0088
      AAA_33   4 lvGlpGsGKstlaerllkklg 24 
                 lvG++G+GKst ++ l  kl+
  EEA20573.1 108 LVGANGTGKSTALKILSGKLK 128
                 89**********998887776 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.0027
      AAA_33   2 vllvGlpGsGKstlaerllkklg.a 25 
                 v+l G +G+GK+t+ + l+ +++  
  EEA20573.1 378 VVLMGENGTGKTTFCKMLAGAEKpD 402
                 8999************998777654 PP

>> AAA_13  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.3      0.53     2e+02      23      37 ..     110     124 ..     108     133 .. 0.84
   2 !   15.2   0.0   1.8e-05    0.0065      20      76 ..     379     463 ..     370     480 .. 0.63

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.53
      AAA_13  23 GwNGaGKTtLSrllr 37 
                 G+NG+GK+t  ++l+
  EEA20573.1 110 GANGTGKSTALKILS 124
                 9********877765 PP

  == domain 2  score: 15.2 bits;  conditional E-value: 1.8e-05
      AAA_13  20 liYGwNGaGKTtLSrllrslelgetepkfangsieitnge........................eldirVfN....rdFveenls 76 
                 ++ G NG+GKTt++++l+  e+       +  +i+++ ++                        ++++ V+     +dF++++++
  EEA20573.1 379 VLMGENGTGKTTFCKMLAGAEKPDGTVSIPRMNISMKPQKitpkftgtvrqlffkrikaaflnpQFQTDVYKplriDDFIDQEVQ 463
                 678****************988666666666666665554445555555555555555555555555555543333466666544 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.0      0.03        11       3      24 ..     108     129 ..     106     156 .. 0.84
   2 !    9.9   0.0    0.0025      0.92       1      19 [.     378     396 ..     378     410 .. 0.91

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.03
  RNA_helicase   3 lyGpsgeGKStlakeLakallk 24 
                   l+G++g+GKSt+ k L+ +l  
    EEA20573.1 108 LVGANGTGKSTALKILSGKLKP 129
                   78************99888764 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.0025
  RNA_helicase   1 iwlyGpsgeGKStlakeLa 19 
                   ++l G++g+GK+t++k La
    EEA20573.1 378 VVLMGENGTGKTTFCKMLA 396
                   6899************987 PP

>> Fer4_21  4Fe-4S dicluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1  11.3   1.2e-05    0.0045       1      58 [.       9      71 ..       9      72 .. 0.77

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 1.2e-05
     Fer4_21  1 AridedkCi..gC.gkCliaCe..dtshqaieidaktvlkvv.edeCvGCnlCssvCPvedcie 58
                A++++dkC   +C ++C ++C+   t+  +ie++++++++ + e  C+GC +C + CP  ++i+
  EEA20573.1  9 AIVNSDKCKpkKCrQECKKSCPvvRTGKLCIEVTPESKIAFIsERLCIGCGICPKKCPF-GAIH 71
                67788888433673368888873347899******99998874779************7.8886 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0     0.065        24      38      58 ..     108     128 ..      90     170 .. 0.90
   2 !   10.7   0.0   0.00073      0.27      34      95 ..     376     440 ..     369     457 .. 0.69

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.065
       AAA_7  38 lvGptGtGKtviikdllkkld 58 
                 lvG  GtGK++ +k l  kl+
  EEA20573.1 108 LVGANGTGKSTALKILSGKLK 128
                 8**********9998777776 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 0.00073
       AAA_7  34 kpvllvGptGtGKtviikdllkkldke.kyls..ltinfsaqtsanqlqdiiesklekrrkgvyg 95 
                   v+l+G+ GtGKt+ +k l  + +++ ++++  ++i+++ q    ++  ++ + + kr k  + 
  EEA20573.1 376 EIVVLMGENGTGKTTFCKMLAGAEKPDgTVSIprMNISMKPQKITPKFTGTVRQLFFKRIKAAFL 440
                 56899*************96655554404443124555556666667777777777777776665 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0       1.2   4.3e+02      18      41 ..      99     125 ..      80     133 .. 0.76
   2 !   14.0   0.0    0.0001     0.038      19      44 ..     375     400 ..     355     415 .. 0.74

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 1.2
                 H...TEEEEEEESTTSSHHHHHHHHHH CS
        TsaE  18 l...gdvilLeGdLGaGKTtlvrglak 41 
                 +   g+v+ L G  G+GK+t  + l  
  EEA20573.1  99 MprpGQVLGLVGANGTGKSTALKILSG 125
                 145578899***********9887765 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 0.0001
                 TEEEEEEESTTSSHHHHHHHHHHHTT CS
        TsaE  19 gdvilLeGdLGaGKTtlvrglakalg 44 
                 +++++L G+ G+GKTt+++ la a +
  EEA20573.1 375 SEIVVLMGENGTGKTTFCKMLAGAEK 400
                 568****************9997755 PP

>> Fer4_6  4Fe-4S binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   2.7     0.033        12       2      20 ..       9      30 ..       8      35 .. 0.87
   2 !   16.3   2.2   2.1e-05    0.0077       2      24 .]      48      70 ..      47      70 .. 0.92

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.033
      Fer4_6  2 veidpdkCi..gCgd.CvrvCP 20
                + ++ dkC    C+  C + CP
  EEA20573.1  9 AIVNSDKCKpkKCRQeCKKSCP 30
                6799****9888*888****** PP

  == domain 2  score: 16.3 bits;  conditional E-value: 2.1e-05
      Fer4_6  2 veidpdkCigCgdCvrvCPegai 24
                + i + +CigCg C + CP+gai
  EEA20573.1 48 AFISERLCIGCGICPKKCPFGAI 70
                678899****************8 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.5   0.0    0.0055       2.1      17      79 ..     101     163 ..      92     182 .. 0.80
   2 ?    4.8   0.1     0.036        14      19      38 ..     374     393 ..     357     400 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0055
                 TSCSEEEEEEESTTSSHHHHHHHHCCSHCCCCCCBT.EEEEEEEESXXHHHHHHHXXHHHHHCC CS
      NB-ARC  17 elqslvvalvGmgGvGKttlakqilnksdevegrFd.svawvvvsktdkseeiletilkeLsls 79 
                  ++  v++lvG  G GK+t +k    k++   gr+d    w  + k +  +e+++   k+L+++
  EEA20573.1 101 RPG-QVLGLVGANGTGKSTALKILSGKLKPNLGRYDdPPDWQEILKYFRGSELQNYFTKVLEDN 163
                 555.69*************999999999999999996778888888888888888888888665 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.036
                 CSEEEEEEESTTSSHHHHHH CS
      NB-ARC  19 qslvvalvGmgGvGKttlak 38 
                 +s +v l+G  G GKtt  k
  EEA20573.1 374 DSEIVVLMGENGTGKTTFCK 393
                 5569*************876 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.3     0.083        31       4      23 ..     108     127 ..     106     134 .. 0.86
   2 ?    8.3   0.0    0.0057       2.1       2      22 ..     378     398 ..     377     423 .. 0.80
   3 ?   -1.6   0.0       6.6   2.5e+03      24      48 ..     489     513 ..     424     540 .. 0.66

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.083
                 EE--SSSSHHHHHHHGGGGB CS
       AAA_5   4 LvGppGtgKselaerlaaal 23 
                 LvG+ GtgKs+  + l+  l
  EEA20573.1 108 LVGANGTGKSTALKILSGKL 127
                 9**********999998877 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.0057
                 EEEE--SSSSHHHHHHHGGGG CS
       AAA_5   2 vlLvGppGtgKselaerlaaa 22 
                 v+L G+ GtgK+++ + la a
  EEA20573.1 378 VVLMGENGTGKTTFCKMLAGA 398
                 89************9999876 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 6.6
                 S--EEEEE--TT--HHHHH--B--. CS
       AAA_5  24 nreveyvqltrdtteedlkgrreik 48 
                   +  y    +++t++ ++ r  ++
  EEA20573.1 489 DEPSAYLDAEQRITASRVIKRFIMN 513
                 4455555566666666666666666 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.3      0.13        48       3      24 ..     106     127 ..     104     131 .. 0.82
   2 ?   -2.1   0.0       8.3   3.1e+03     111     155 ..     154     195 ..     150     197 .. 0.80
   3 ?    9.8   0.1    0.0018      0.68       2      21 ..     377     396 ..     376     403 .. 0.88

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.13
                 EEEEC-TTTCHHHHHHHHHHHH CS
       NACHT   3 vilqGeaGsGKTtLlqklalaw 24 
                 + l G++G GK+t l+ l  ++
  EEA20573.1 106 LGLVGANGTGKSTALKILSGKL 127
                 5689**********99887665 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 8.3
                 HHHCTTTTT--EEEEEEECCCHHHHCTTSSCE..EEEE--TCCHH CS
       NACHT 111 elirkkllpeasllltvrpralrdleeqleeaivlevegfsesrr 155
                 + ++k  + e  l++ v+p+ + ++++ ++ + v ev++++e r 
  EEA20573.1 154 NYFTK--VLEDNLKAVVKPQYVDQIPRAVKGP-VKEVGPLIEARS 195
                 55666..55667889999****99*****999.999999998875 PP

  == domain 3  score: 9.8 bits;  conditional E-value: 0.0018
                 CEEEEC-TTTCHHHHHHHHH CS
       NACHT   2 lvilqGeaGsGKTtLlqkla 21 
                 +v+l Ge+G GKTt+ + la
  EEA20573.1 377 IVVLMGENGTGKTTFCKMLA 396
                 699************99887 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0      0.15        55       3      25 ..     104     126 ..     102     169 .. 0.82
   2 ?    7.8   0.1    0.0084       3.1       2      43 ..     375     417 ..     374     522 .. 0.74

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.15
      AAA_14   3 kilvitGaRrvGKTtllkqlike 25 
                 ++l ++Ga  +GK+t lk l  +
  EEA20573.1 104 QVLGLVGANGTGKSTALKILSGK 126
                 68899***********9877554 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0084
      AAA_14   2 rkilvitGaRrvGKTtllkqlikell.vkkesilyinldderd 43 
                 ++i+v++G   +GKTt++k l+  +      si  +n+  +++
  EEA20573.1 375 SEIVVLMGENGTGKTTFCKMLAGAEKpDGTVSIPRMNISMKPQ 417
                 579*****************99887743344444555544444 PP

>> VirE  Virulence-associated protein E
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.0     0.013       4.7      53      75 ..     104     126 ..      88     172 .. 0.84
   2 ?    5.2   0.0     0.041        15      53      73 ..     376     397 ..     369     403 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.013
        VirE  53 fvlvLvGkqgsgKstfleklgee 75 
                 +vl LvG+ g+gKst l++l+++
  EEA20573.1 104 QVLGLVGANGTGKSTALKILSGK 126
                 6899****************765 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.041
        VirE  53 fvlvLvGkqgsgKstflekl.g 73 
                 +++vL G+ g+gK+tf + l g
  EEA20573.1 376 EIVVLMGENGTGKTTFCKMLaG 397
                 689***************9944 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.1     0.069        26      33      50 ..     103     120 ..      92     126 .. 0.87
   2 ?    7.7   0.0    0.0064       2.4      32      54 ..     374     396 ..     367     399 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.069
      AAA_25  33 gelallaGapgtGKttla 50 
                 g +  l+Ga gtGK+t++
  EEA20573.1 103 GQVLGLVGANGTGKSTAL 120
                 677789**********86 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0064
      AAA_25  32 agelallaGapgtGKttlaldla 54 
                   e+++l+G  gtGKtt++  la
  EEA20573.1 374 DSEIVVLMGENGTGKTTFCKMLA 396
                 57899************986665 PP

>> Fer4_10  4Fe-4S dicluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   6.3     0.054        20       2      21 ..       9      31 ..       8      49 .. 0.79
   2 ?   14.9   1.6   5.8e-05     0.022       4      23 ..      50      69 ..      46      93 .. 0.74

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.054
     Fer4_10  2 vvidddtC..irCg.kCvkaCPa 21
                +++++d+C   +C+ +C+k+CP+
  EEA20573.1  9 AIVNSDKCkpKKCRqECKKSCPV 31
                578999**6669*99*******9 PP

  == domain 2  score: 14.9 bits;  conditional E-value: 5.8e-05
     Fer4_10  4 idddtCirCgkCvkaCPadl 23
                i +  Ci+Cg C k CP+ +
  EEA20573.1 50 ISERLCIGCGICPKKCPFGA 69
                77889************955 PP

>> SRP54  SRP54-type protein, GTPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.5      0.06        22       3      25 ..     105     127 ..     103     133 .. 0.81
   2 ?   10.1   0.1    0.0012      0.44       2      23 ..     376     397 ..     375     406 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.06
                 EEEEEESTTSSHHHHHHHHHHHH CS
       SRP54   3 villvGlqGaGKTttlaKLaall 25 
                 v+ lvG +G+GK t+l  L+ +l
  EEA20573.1 105 VLGLVGANGTGKSTALKILSGKL 127
                 5669**********998777665 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.0012
                 EEEEEEESTTSSHHHHHHHHHH CS
       SRP54   2 nvillvGlqGaGKTttlaKLaa 23 
                 ++++l+G +G+GKTt +  La 
  EEA20573.1 376 EIVVLMGENGTGKTTFCKMLAG 397
                 5799*************99986 PP

>> Thymidylate_kin  Thymidylate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.0     0.017       6.5       3      46 ..     110     151 ..     108     165 .. 0.79
   2 ?    4.9   0.1     0.051        19       3      18 ..     382     397 ..     381     408 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.017
                      ESTTSSHHHHHHHHHHHHHHTTE.EEEESSSTTSHHHHHHHHHH CS
  Thymidylate_kin   3 GlDGaGKttqaellkerlkeegikvvltrepggteiGekirell 46 
                      G +G+GK+t +++l  +lk +  +     +p+  ei + +r++ 
       EEA20573.1 110 GANGTGKSTALKILSGKLKPNLGR--YDDPPDWQEILKYFRGSE 151
                      899***************998865..666666666666666655 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.051
                      ESTTSSHHHHHHHHHH CS
  Thymidylate_kin   3 GlDGaGKttqaellke 18 
                      G +G+GKtt++++l+ 
       EEA20573.1 382 GENGTGKTTFCKMLAG 397
                      668**********985 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.0      0.03        11      58      77 ..     108     127 ..      98     131 .. 0.83
   2 ?    5.6   0.0      0.02       7.5      55      81 ..     377     403 ..     369     434 .. 0.79

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.03
      DUF815  58 LwGarGtGKSslvkallney 77 
                 L+Ga GtGKS+ +k l  ++
  EEA20573.1 108 LVGANGTGKSTALKILSGKL 127
                 99***********9987665 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.02
      DUF815  55 nvLLwGarGtGKSslvkallneyaeeg 81 
                  v+L+G+ GtGK + +k l  + + +g
  EEA20573.1 377 IVVLMGENGTGKTTFCKMLAGAEKPDG 403
                 589**************9987766655 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.1     0.041        15       3      22 ..     107     126 ..     105     136 .. 0.85
   2 ?    5.8   0.0     0.037        14       2      22 ..     378     398 ..     377     524 .. 0.73

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.041
                 EEEESTTSSHHHHHHHHHTS CS
    MMR_HSR1   3 aivGrpNvGKStLinaltge 22 
                 ++vG   +GKSt ++ l+g+
  EEA20573.1 107 GLVGANGTGKSTALKILSGK 126
                 89*************99997 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.037
                 EEEEESTTSSHHHHHHHHHTS CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltge 22 
                 v+++G   +GK+t+ + l g+
  EEA20573.1 378 VVLMGENGTGKTTFCKMLAGA 398
                 799***************984 PP

>> DLIC  Dynein light intermediate chain (DLIC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.1       8.9   3.3e+03      30      50 ..     108     128 ..      99     133 .. 0.74
   2 ?   11.4   0.0   0.00027       0.1      21      52 ..     371     402 ..     366     419 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 8.9
        DLIC  30 vlGedgsGkttliaklqGvee 50 
                 ++G +g+Gk+t +  l G  +
  EEA20573.1 108 LVGANGTGKSTALKILSGKLK 128
                 789*******99988888655 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00027
        DLIC  21 klPsgksvlvlGedgsGkttliaklqGveeek 52 
                 k+  +  v+++Ge+g+Gktt+   l G+e++ 
  EEA20573.1 371 KFTDSEIVVLMGENGTGKTTFCKMLAGAEKPD 402
                 666677899*******************9875 PP

>> PduV-EutP  Ethanolamine utilisation - propanediol utilisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.3       3.7   1.4e+03       6      23 ..     108     125 ..     104     128 .. 0.86
   2 ?   12.1   0.1   0.00033      0.12       3      24 ..     377     398 ..     375     401 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 3.7
   PduV-EutP   6 liGkvgsGKttLtqalkg 23 
                 l+G+ g+GK t  + l+g
  EEA20573.1 108 LVGANGTGKSTALKILSG 125
                 89********99998887 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 0.00033
   PduV-EutP   3 killiGkvgsGKttLtqalkge 24 
                  ++l+G+ g+GKtt ++ l g 
  EEA20573.1 377 IVVLMGENGTGKTTFCKMLAGA 398
                 699***************9986 PP

>> Fer4_9  4Fe-4S dicluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3  11.7    0.0004      0.15       4      51 .]      20      70 ..      14      70 .. 0.61

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.0004
      Fer4_9  4 gCga.CveaCpagvvvedaaerkarlraase......eaCigCgaCveaCpkgai 51
                +C++ C ++C     v + ++  ++++ +s+        CigCg C ++Cp gai
  EEA20573.1 20 KCRQeCKKSC----PVVRTGKLCIEVTPESKiafiseRLCIGCGICPKKCPFGAI 70
                3442355555....4444444444444444444556689************9987 PP

>> Fer4_16  4Fe-4S double cluster binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   2.4       3.1   1.2e+03       4      14 ..      20      31 ..      10      49 .. 0.82
   2 ?   13.9   0.3   0.00021     0.078       2      18 ..      55      71 ..      54      98 .. 0.79

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 3.1
     Fer4_16  4 tCgk.CaevCPt 14
                +C++ C ++CP+
  EEA20573.1 20 KCRQeCKKSCPV 31
                677778888886 PP

  == domain 2  score: 13.9 bits;  conditional E-value: 0.00021
     Fer4_16  2 CgtCgkCaevCPtnaik 18
                C++Cg C + CP +ai+
  EEA20573.1 55 CIGCGICPKKCPFGAIH 71
                ***************86 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.1       3.6   1.3e+03      19      34 ..     103     118 ..     101     120 .. 0.85
   2 ?   11.4   0.1    0.0004      0.15      13      37 ..     369     393 ..     355     405 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 3.6
      ATPase  19 grvvlitGepGtGKti 34 
                 g+v  ++G  GtGK++
  EEA20573.1 103 GQVLGLVGANGTGKST 118
                 5778899*******96 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.0004
      ATPase  13 kgGipegrvvlitGepGtGKtifal 37 
                 +g + + ++v ++Ge GtGKt+f++
  EEA20573.1 369 SGKFTDSEIVVLMGENGTGKTTFCK 393
                 5889999****************97 PP

>> KAP_NTPase  KAP family P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0     0.064        24      16      46 ..      99     129 ..      86     220 .. 0.89
   2 ?    5.7   0.0     0.019       7.2      18      45 ..     373     400 ..     358     522 .. 0.90

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.064
  KAP_NTPase  16 tlatpivvgLygkWGsGKssllnkledelke 46 
                  ++++ v+gL g+ G+GKs+ l+ l  +lk 
  EEA20573.1  99 MPRPGQVLGLVGANGTGKSTALKILSGKLKP 129
                 457899*****************99988875 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.019
  KAP_NTPase  18 atpivvgLygkWGsGKssllnkledelk 45 
                 +++ +v+L g+ G+GK++++++l  + k
  EEA20573.1 373 TDSEIVVLMGENGTGKTTFCKMLAGAEK 400
                 6677899***************987766 PP

>> MukB  MukB N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.0     0.035        13      28      54 ..     105     131 ..      97     135 .. 0.85
   2 ?   -1.5   0.0       4.9   1.8e+03      96     114 ..     200     218 ..     190     245 .. 0.73
   3 ?    3.5   0.0      0.14        52      25      53 ..     374     402 ..     362     409 .. 0.83

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.035
                 HHHHHS--SHHHHHHHHHHHHHHS--T CS
        MukB  28 vttlsGgnGaGksttmaafvtaliPdl 54 
                 v  l G+nG+Gkst++  +   l P+l
  EEA20573.1 105 VLGLVGANGTGKSTALKILSGKLKPNL 131
                 67899**********998888888776 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 4.9
                 S-EEEEEEEEEE-SSTTT- CS
        MukB  96 eqrllvgvrleqvagrdkk 114
                  +r++  ++l+qv +rd  
  EEA20573.1 200 MDRIMDVLELKQVENRDIN 218
                 5688888899999999965 PP

  == domain 3  score: 3.5 bits;  conditional E-value: 0.14
                 HHHHHHHHS--SHHHHHHHHHHHHHHS-- CS
        MukB  25 delvttlsGgnGaGksttmaafvtaliPd 53 
                 d+ +  l G nG+Gk+t    +  a  Pd
  EEA20573.1 374 DSEIVVLMGENGTGKTTFCKMLAGAEKPD 402
                 778899***********877777776666 PP

>> Fer4_8  4Fe-4S dicluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   2.0      0.85   3.2e+02       8      20 ..      21      34 ..      14      48 .. 0.78
   2 ?   11.6   0.2   0.00078      0.29       5      18 ..      55      68 ..      51     104 .. 0.76

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.85
      Fer4_8  8 C.gaCqsaCpvlrr 20
                C + C+++Cpv+r+
  EEA20573.1 21 CrQECKKSCPVVRT 34
                53479999999987 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 0.00078
      Fer4_8  5 CieCgaCqsaCpvl 18
                Ci+Cg C ++Cp+ 
  EEA20573.1 55 CIGCGICPKKCPFG 68
                ***********953 PP

>> CLP1_P  mRNA cleavage and polyadenylation factor CLP1 P-loop
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.2      0.39   1.5e+02       1      18 [.     110     127 ..     110     133 .. 0.88
   2 ?    6.9   0.1     0.014         5       1      15 [.     382     396 ..     382     403 .. 0.91

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.39
      CLP1_P   1 GpkdsGKSTlarlLlNya 18 
                 G++ +GKST  ++L  ++
  EEA20573.1 110 GANGTGKSTALKILSGKL 127
                 8899**********9876 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.014
      CLP1_P   1 GpkdsGKSTlarlLl 15 
                 G++ +GK+T++++L+
  EEA20573.1 382 GENGTGKTTFCKMLA 396
                 8899**********8 PP

>> Fer4_7  4Fe-4S dicluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   3.5         2   7.4e+02      33      50 ..      11      31 ..       3      33 .. 0.76
   2 ?    6.7  13.9      0.03        11       4      52 .]      20      69 ..      15      69 .. 0.75
   3 ?   13.7   1.6   0.00019     0.069       2      19 ..      55      72 ..      54      88 .. 0.83

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 2
      Fer4_7 33 idpekCl..gCga.CvavCPt 50
                ++++kC    C++ C + CP+
  EEA20573.1 11 VNSDKCKpkKCRQeCKKSCPV 31
                56889954489988*****97 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.03
      Fer4_7  4 gCg.aCvaaCpvkaieldeeenekgtekveidpekClgCgaCvavCPtga 52
                +C+  C + Cpv        e+ ++ + + i+++ C+gCg C + CP+ga
  EEA20573.1 20 KCRqECKKSCPVVRTGKLCIEVTPESKIAFISERLCIGCGICPKKCPFGA 69
                57558999999554444444566666777888999*************98 PP

  == domain 3  score: 13.7 bits;  conditional E-value: 0.00019
      Fer4_7  2 CigCgaCvaaCpvkaiel 19
                CigCg C + Cp +ai +
  EEA20573.1 55 CIGCGICPKKCPFGAIHI 72
                99*********9999976 PP

>> Fer4_2  4Fe-4S binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   2.0       1.1   4.3e+02       4      21 ..      10      30 ..       7      31 .. 0.71
   2 ?   11.5   1.2   0.00067      0.25       4      21 ..      49      66 ..      46      67 .. 0.81

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 1.1
      Fer4_2  4 vvdtdrCi.g.Cg.aCvsaCP 21
                 v++d+C    C+  C ++CP
  EEA20573.1 10 IVNSDKCKpKkCRqECKKSCP 30
                688999953348778888898 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 0.00067
      Fer4_2  4 vvdtdrCigCgaCvsaCP 21
                ++ ++ CigCg+C + CP
  EEA20573.1 49 FISERLCIGCGICPKKCP 66
                667889*******77788 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.2      0.46   1.7e+02       4      24 ..     108     128 ..     105     132 .. 0.85
   2 ?   -2.1   0.0       8.6   3.2e+03     114     134 ..     258     278 ..     224     290 .. 0.64
   3 ?    6.0   0.2     0.028        11       2      21 ..     378     397 ..     377     405 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.46
                 EE--TTSSHHHHHHHHHHHH. CS
    NTPase_1   4 iTGppGvGKtTlvkkvlellk 24 
                 + G  G+GK+T +k ++ +lk
  EEA20573.1 108 LVGANGTGKSTALKILSGKLK 128
                 7799*********99998886 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 8.6
                 HHHHHHHHHTTTSEEEEE--S CS
    NTPase_1 114 fkeaveevLksekpvlavihr 134
                  +++++e+L+++  v++v h 
  EEA20573.1 258 AARTIRELLRPDDYVIVVEHD 278
                 356788888888888877665 PP

  == domain 3  score: 6.0 bits;  conditional E-value: 0.028
                 EEEE--TTSSHHHHHHHHHH CS
    NTPase_1   2 vfiTGppGvGKtTlvkkvle 21 
                 v++ G+ G+GKtT++k ++ 
  EEA20573.1 378 VVLMGENGTGKTTFCKMLAG 397
                 6899***********98775 PP

>> Fer4_17  4Fe-4S dicluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3  11.3       1.4   5.1e+02      44      58 ..      53      67 ..      15      70 .. 0.70
   2 ?   12.2   0.8   0.00055      0.21       2      17 ..      55      70 ..      54      98 .. 0.67

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 1.4
     Fer4_17 44 slCieCgeCerkCPq 58
                 lCi+Cg C +kCP 
  EEA20573.1 53 RLCIGCGICPKKCPF 67
                578888888888885 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 0.00055
     Fer4_17  2 CiqCgyClpeCpsyea 17
                Ci+Cg C ++Cp++++
  EEA20573.1 55 CIGCGICPKKCPFGAI 70
                8888888888888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (604 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       651  (0.0363099); expected 358.6 (0.02)
Passed bias filter:                      536  (0.0298957); expected 358.6 (0.02)
Passed Vit filter:                       117  (0.00652574); expected 17.9 (0.001)
Passed Fwd filter:                        50  (0.00278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              48  [number of targets reported over threshold]
# CPU time: 0.74u 0.30s 00:00:01.04 Elapsed: 00:00:00.46
# Mc/sec: 3924.62
//
Query:       EEA20574.1  [L=1497]
Description: chromodomain helicase (Chd1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.7e-55  188.2   0.0    2.6e-55  187.6   0.0    1.2  1  SNF2_N           SNF2 family N-terminal domain
    7.8e-21   73.7   2.2    7.5e-13   48.2   0.4    3.2  2  Chromo           Chromo (CHRromatin Organisation MOdifier) do
    2.1e-20   73.1   0.0    5.1e-20   71.9   0.0    1.7  1  Helicase_C       Helicase conserved C-terminal domain
    4.7e-10   39.8   0.0    4.7e-10   39.8   0.0    2.4  3  DUF4208          Domain of unknown function (DUF4208)
    4.8e-08   32.5   0.0    1.2e-07   31.2   0.0    1.6  1  HDA2-3           Class II histone deacetylase complex subunit
    2.4e-07   30.9   0.0    7.9e-05   22.7   0.0    2.9  2  ResIII           Type III restriction enzyme, res subunit
    6.3e-06   26.5  17.4    6.7e-05   23.2   0.8    4.4  4  Cdh1_DBD_1       Chromodomain helicase DNA-binding domain 1
  ------ inclusion threshold ------
      0.016   15.4   0.2      0.075   13.2   0.0    2.3  2  CHDCT2           CHDCT2 (NUC038) domain


Domain annotation for each model (and alignments):
>> SNF2_N  SNF2 family N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  187.6   0.0   1.2e-58   2.6e-55      53     349 ..     460     727 ..     443     728 .. 0.87

  Alignments for each domain:
  == domain 1  score: 187.6 bits;  conditional E-value: 1.2e-58
                 HTT--EEE---TTS--HHHHHHHHH...HHTTTS---.......S-EEEE--HHHHHHHHHHHHHH-TTS-EEE--SSHHHH...-------------- CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxx RF
      SNF2_N  53 qsvrGGiLaDemGLGKTvqvlalilaqrakeekdkekkrkdtlagptLivvPaslldqWeneierhvsssalrvlvyggqkk...mkkkntkvapklla 148
                 + +++ +LaDemGLGKTvq++a+i      ++ +          gp+++vvP s++  W +++e ++++ +  v+++++q +   ++ +  k  +    
  EEA20574.1 460 SRNQNVVLADEMGLGKTVQTIAFIN---WLRHVRG-------QDGPFIVVVPLSTIPSWSETFEYWTPDVNYIVYTGSSQARqilKDYELMKDGNPRKP 548
                 5667789******************...4445555.......459*************************99999999988855522222333345678 PP

                 ---EEEE-HHHHHHHT......TTS-S-S-SEEEES-GGGT--TTSHHHHHHHH---S-EEEE-S--SSS-HHHHHHHHHHH-TTTT--HHHHHHHTHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      SNF2_N 149 dydvvittYdvlsreaelqkkrsvlkqvewkrvvlDEghtlknstskaaeavskLstsnrwiltGTPiqnsledlygLlkfLreepfgekqtfdkllqr 247
                 +++v++tt+++ + +       + l q  w+++ +DE+h+lkn +s+++  ++++++  r+++tGTPiqn+l++l +L++fL+++  +        l+ 
  EEA20574.1 549 KFNVMLTTFEYANMDF------DFLRQFPWQFMAVDEAHRLKNRESNLYGNLLDFKAPARLLITGTPIQNNLAELSALMDFLNPGLVEVEVDM--DLSS 639
                 99***********888......9***************************************************************9943333..3333 PP

                 HHHHHHHHHHHHHHTT-STTEE---GGGT--S---EEEEEEEEE--HHHHHHHH....................HHHHHH-HH.H-HHHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxx RF
      SNF2_N 248 pieaqaekgrsrLlqllqrlmlrrakkdveknlPpkteeiiflklskverksYnrllevlrkkalakllkrseaalksssksk.ekilelllelrqacn 345
                 +   qa ++ ++L + l++lmlrr+k++ve +lPpkte+ii+++ls+ ++++Y+             +l+++ aal+++ + + + +l++++el++a n
  EEA20574.1 640 E---QASEKLAKLQNTLKPLMLRRTKSKVETDLPPKTEKIIRVELSDIQLEYYK------------NILTKNYAALNEGANGQkQSLLNIMMELKKASN 723
                 3...55789*********************************************............88888999999999888777************* PP

                 ---X CS
                 xxxx RF
      SNF2_N 346 hpql 349
                 hp +
  EEA20574.1 724 HPFM 727
                 **88 PP

>> Chromo  Chromo (CHRromatin Organisation MOdifier) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.1   1.3e-08     3e-05       3      46 ..     258     314 ..     256     321 .. 0.83
   2 !   48.2   0.4   3.4e-16   7.5e-13       2      54 .]     359     409 ..     358     409 .. 0.94

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 1.3e-08
                 EEEEEEEEEETTEEC...........EEEEEEETTSTGGGTEEEEGGGCSSH..SHH CS
      Chromo   3 VerIidhrtdkdgle...........leYlVKWkglpysentWEpeenlekc..fqe 46 
                 ++ ++dhr +++                Y++KW++ ++ ++tWE+ + l+ +  f++
  EEA20574.1 258 IDFVLDHRLKDGVDPnisdtdvtirdCLYYIKWQNQSHYHATWESSDSLKYHtgFRR 314
                 678999998888888899999999999******************999976555555 PP

  == domain 2  score: 48.2 bits;  conditional E-value: 3.4e-16
                 EEEEEEEEEEETTEECEEEEEEETTSTGGGTEEEEGGGCSSHSHHHHHHHHHH CS
      Chromo   2 eVerIidhrtdkdgleleYlVKWkglpysentWEpeenlekcfqelideFkkr 54 
                 +V+rIi+hr   dg   eY+VKWk+l+y+ +tWE+ +++++ + + +d+F +r
  EEA20574.1 359 KVDRIIGHRDTLDGT--EYFVKWKRLNYDACTWESDSLVKEIAIDELDQFLDR 409
                 7********999999..9************************99999999987 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.9   0.0   2.3e-23   5.1e-20       3     111 .]     756     868 ..     754     868 .. 0.91

  Alignments for each domain:
  == domain 1  score: 71.9 bits;  conditional E-value: 2.3e-23
                 HHHHHHHH.HHTTTTSEEEEEESSHHHHHH.HHHHHHHT.TSTEEEESTTSTHHHHHHHHHHHH...TTSSSEEEESGGGTSSSTSTTESEEEESSSSS CS
  Helicase_C   3 leallell.kleeeggkilifvntidrlek.vklllekk.gikvavlhgelpqnereeileqfn...kgesdvLiatdvaerGidipkvnlVinfdlpr 95 
                 +  l +ll kl+++g+++lif++ +++l+   +++  ++ g+++ +l+g++++ +r+ ++e fn   + ++ +L++t++++ Gi++  +++Vi fd ++
  EEA20574.1 756 MMLLDQLLaKLKRDGHRVLIFSQMVKMLDLlGDYM--RFrGYQYQRLDGTISAANRRVAMEHFNapeSSDFAFLLSTRAGGLGINLMTADTVILFDSDW 852
                 55677787899*****************8776777..6679***********************87667788*************************** PP

                 SHHHHHHHHTTSSSTT CS
  Helicase_C  96 nvtsyiqriGRtgRag 111
                 n++   q++ R++R+g
  EEA20574.1 853 NPQADLQAMARAHRIG 868
                 **************97 PP

>> DUF4208  Domain of unknown function (DUF4208)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.2         8   1.8e+04       8      27 ..     639     658 ..     634     674 .. 0.63
   2 ?   -3.4   0.2         6   1.3e+04      12      39 ..    1128    1153 ..    1115    1157 .. 0.54
   3 !   39.8   0.0   2.1e-13   4.7e-10      12      96 .]    1402    1484 ..    1394    1484 .. 0.90

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 8
     DUF4208   8 eeeckellrpvkksLkrLkk 27 
                 +e+  e+l  ++++Lk L  
  EEA20574.1 639 SEQASEKLAKLQNTLKPLML 658
                 44456666666666666653 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 6
     DUF4208   12 kellrpvkksLkrLkkltkekllskker 39  
                   +l r  +++L+++++    k+++kke+
  EEA20574.1 1128 AQLVREDREKLEEMERSG--KIPTKKEK 1153
                  444555556666666553..33555554 PP

  == domain 3  score: 39.8 bits;  conditional E-value: 2.1e-13
     DUF4208   12 kellrpvkksLkrLkkltkekllskkerakilkkeLlkiGdfIdellkekkeekkeklkkhlWefvs..kfwpkkvsgkkLeemYkk 96  
                   ++++p  + L++L++ +k + ++k++ra+++++ +lkiG+fI++ll++   ++   l+++lW +v+   f p k++ + +++mY+k
  EEA20574.1 1402 DSIFEPKAHLLHKLRDVKK-NNPDKEQRANEMRRLILKIGNFIKQLLRN---DNYPGLEDRLWGHVAknCFPPGKATLESIKNMYEK 1484
                  57899999*******9955.58*************************99...699************74466688**********97 PP

>> HDA2-3  Class II histone deacetylase complex subunits 2 and 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.2   0.0   5.5e-11   1.2e-07      21     247 ..     674     892 ..     670     907 .. 0.77

  Alignments for each domain:
  == domain 1  score: 31.2 bits;  conditional E-value: 5.5e-11
                 HHHHHHTHHHHHHHHHSTTT--HHHH.........HHHHHHHH.HHHHHHH-GGGT--...TT--S-S-STTHHHHHHHT-HHHHHHHHHHHHHTTSS. CS
      HDA2-3  21 eqivslhyedllkyvetsdsqeklsls........ikslticlenlslvanHPsLLvd...HympkklllkelpeklaetSgKFkvlndlvnliierkr 108
                 e+i++ + +d+  ++  +  +++++          +++l+i++ +l+  +nHP +  +    + + +  +++l  +++++SgK+ +l +l+  +  +  
  EEA20574.1 674 EKIIRVELSDIQLEYYKNILTKNYAALnegangqkQSLLNIMM-ELKKASNHPFMFPNaeaKLLEGNTRREDLLRIMITSSGKMMLLDQLLAKLKRDG- 770
                 5555555555544442222222222222344444477899999.99*********865223578889999************************9999. PP

                 ...EEEEEEE-STHHHHHHHHHHTTSSSEEEESSS--S--S---S-..................-SEEEEEEESS---TTTS--TT-S-EEEEEE-SST CS
      HDA2-3 109 ksslnvlvvakskkeldLiEalllGkklkikrysgeklydekkkkskdtkknsrktkeklkkkihsltihllsttrqltkdksllenikfdliiafDss 207
                      vl+ ++ +k ldL+  ++  ++ +++r++g+ ++  ++ ++            +  +   s+++ +l +tr         + + +d +i fDs+
  EEA20574.1 771 ---HRVLIFSQMVKMLDLLGDYMRFRGYQYQRLDGT-ISAANRRVA-----------MEHFNAPESSDFAFLLSTRAGGLG---INLMTADTVILFDSD 851
                 ...99*****************************98.566666666...........122345678999999999988555...556678********* PP

                 --TTSHHHHHHH---.-------EEEEEETTSHHHHHHHHT CS
      HDA2-3 208 vdtsspsveslrtqn.rkknklpiirlvpinSieHvkLcfk 247
                  +++ +   + r ++  + +++ ++rlv+ ++ie   L++ 
  EEA20574.1 852 WNPQADLQAMARAHRiGQTRPVSVYRLVSKDTIEEEVLERA 892
                 *****9999999887244556*************9888877 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   0.0   3.5e-08   7.9e-05      12     170 ..     452     610 ..     436     611 .. 0.74
   2 ?    4.8   0.0     0.011        24       6      67 ..     705     783 ..     701     831 .. 0.81

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 3.5e-08
                 HHHHT......TTSEEEEEESTTSTHHHHHHHHHHHH-S......-EEEEESSHHHHHHHHHHGGGGTGG...........GEEEESSS-B--...... CS
      ResIII  12 ienlleklkskrdkrglikmaTGtGKTlvaaklierllkkgkee.kflflvprkslleqtleefkkflseayke.......igkkvsgdkkka...... 96 
                 ++ l+ ++   r+++++++ + G GKT+  +++i  l++ ++++  f+++vp  ++   + e+f+ ++++ +         +          +      
  EEA20574.1 452 LNFLAYNW--SRNQNVVLADEMGLGKTVQTIAFINWLRHVRGQDgPFIVVVPLSTIP-SWSETFEYWTPDVNYIvytgssqA----------Rqilkdy 537
                 44444444..6899999*************999999988888777999999988876.699***999999866555444442..........2223344 PP

                 ............-SEEEEEHHHHHHTH........HHHTTT-S..EEEEETGGGTTS...TTTHHHHHT---SEEEEEESS-S CS
      ResIII  97 .....kekdstnkkilvttiqsldadseeeeeeseellrdrfd..viiiDEaHrlgak..kswreilekfkeavllglTATpe 170
                       + ++ + ++++tt + ++ d         ++lr+ f+  ++ +DEaHrl+    + + ++l+  k+  +l +T+Tp 
  EEA20574.1 538 elmkdGNPRKPKFNVMLTTFEYANMDF--------DFLRQ-FPwqFMAVDEAHRLKNResNLYGNLLDF-KAPARLLITGTPI 610
                 444465666889999999999999999........34433.33358999*******9844489997776.89999999***95 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.011
                 HHHHHHHHHHT.........................TTSEEEEEESTTSTHHHHHHHHHHHH-S.....-EEEEESSHHHH CS
      ResIII   6 eyQeeaienlleklks...................krdkrglikmaTGtGKTlvaaklierllkkgkeekflflvprksll 67 
                 + Q++ + n++ +lk+                   +r++ +l  m T +GK +++ +l ++l++ g+  ++l++ +  ++l
  EEA20574.1 705 NGQKQSLLNIMMELKKasnhpfmfpnaeakllegnTRREDLLRIMITSSGKMMLLDQLLAKLKRDGH--RVLIFSQMVKML 783
                 579********99999999*************9988888999*********************9999..888876665555 PP

>> Cdh1_DBD_1  Chromodomain helicase DNA-binding domain 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.1       5.9   1.3e+04      53      71 ..     958     976 ..     937     981 .. 0.57
   2 ?   -1.6   1.5       1.4   3.2e+03      54      94 ..    1009    1048 ..     985    1066 .. 0.54
   3 !   23.2   0.8     3e-08   6.7e-05       1      64 [.    1077    1140 ..    1077    1147 .. 0.93
   4 !   13.5   0.1     3e-05     0.067     103     120 .]    1150    1167 ..    1144    1167 .. 0.93

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 5.9
  Cdh1_DBD_1  53 klvkeeeekrakeleelea 71 
                 +++++ ee+++++ e lea
  EEA20574.1 958 SVLANAEEHKTEQTEGLEA 976
                 3444555555555555555 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 1.4
  Cdh1_DBD_1   54 lvkeeeekrakeleeleadaeeykeklkkgevkadeekkdt 94  
                  ++k ee+ r+   + l+  +e+++ + ++ ++ a +e++++
  EEA20574.1 1009 EIKAEEK-RKADEKYLHDVIEQNQPRKRNAPNDAFDEREER 1048
                  3333333.333335555555555555555555554444432 PP

  == domain 3  score: 23.2 bits;  conditional E-value: 3e-08
  Cdh1_DBD_1    1 ltEreiRalYkaiLkyGdlsnkleeliadGtLPeknielleelyeelleeakklvkeeeekrak 64  
                  l+E+e+R l +a L+yGd++++ e+++ +  L  ++ ++++ + + + ++a +lv+e+ ek ++
  EEA20574.1 1077 LKEKELRHLIRAFLRYGDVDEREEDVVREARLVGRDRDTVKAALRAITDKAAQLVREDREKLEE 1140
                  78*****************************************************998887665 PP

  == domain 4  score: 13.5 bits;  conditional E-value: 3e-05
  Cdh1_DBD_1  103 rrekkAiLFeykgvknlN 120 
                  ++ekkA+LF+++gvk +N
  EEA20574.1 1150 KKEKKAVLFDHQGVKRIN 1167
                  89**************99 PP

>> CHDCT2  CHDCT2 (NUC038) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   0.1       7.6   1.7e+04     131     146 ..     758     773 ..     732     779 .. 0.76
   2 ?   13.2   0.0   3.3e-05     0.075       5      45 ..    1209    1249 ..    1206    1323 .. 0.86

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 7.6
      CHDCT2 131 qleelLsdmkadvsrl 146
                  l++lL+ +k d +r+
  EEA20574.1 758 LLDQLLAKLKRDGHRV 773
                 5788888888887775 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 3.3e-05
      CHDCT2    5 WhRrHDyWllagvvlhGyaRwqDiqndprfaiinepFksea 45  
                  W  r D  l +g+v hGy+ w +i +dp + + +  F +e+
  EEA20574.1 1209 WGAREDGMLCIGIVRHGYGAWPEIRDDPDLGLGDKFFLEEH 1249
                  88999999********************9887666555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1497 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1205  (0.0672095); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.99u 0.36s 00:00:01.35 Elapsed: 00:00:00.52
# Mc/sec: 8659.54
//
Query:       EEA20575.1  [L=364]
Description: C2H2 finger domain protein (Gli3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.4e-07   31.6   7.8    2.3e-06   27.8   0.6    3.3  3  zf-H2C2_2    Zinc-finger double domain
      6e-07   29.3   1.5       0.01   15.8   0.0    2.4  2  zf-C2H2_6    C2H2-type zinc finger
    7.1e-06   26.2   0.3    7.1e-06   26.2   0.3    3.7  3  zf-C2H2      Zinc finger, C2H2 type
    7.6e-06   26.5   5.3       0.16   12.6   0.0    3.3  3  FOXP-CC      FOXP coiled-coil domain
    0.00055   20.5   7.5     0.0049   17.6   0.2    3.0  3  zf-C2H2_4    C2H2-type zinc finger
  ------ inclusion threshold ------
       0.19   11.5   0.8       0.53   10.1   0.0    2.0  2  zf-C2H2_11   zinc-finger C2H2-type
       0.45   10.9   2.3        2.6    8.5   0.2    2.8  3  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
       0.49   10.4  12.5        3.5    7.7   4.3    2.8  2  Zap1_zf2     Zap1 zinc finger 2


Domain annotation for each model (and alignments):
>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.3     0.032        72       1      22 [.     123     149 ..     123     151 .. 0.73
   2 !   27.8   0.6     1e-09   2.3e-06       1      26 []     159     186 ..     159     186 .. 0.95
   3 ?    2.8   0.0     0.078   1.8e+02       1      10 [.     189     199 ..     189     207 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.032
   zf-H2C2_2   1 nLrrHir.kHtgekp..yeCp..lCdk 22 
                 nL+ Hi  +H g +   y C+   C+ 
  EEA20575.1 123 NLVNHIHdEHIGTRQkkYSCEwtDCSR 149
                 7999**84599666444***9877865 PP

  == domain 2  score: 27.8 bits;  conditional E-value: 1e-09
   zf-H2C2_2   1 nLrrHirkHtgekpyeCp..lCdkaFkt 26 
                 +Lr H+r+Ht ekp+ C   +Cd +F++
  EEA20575.1 159 ALRAHMRSHTREKPFYCAlpECDRSFTR 186
                 79****************999*****85 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.078
   zf-H2C2_2   1 nLrrHirk.Ht 10 
                 +L +H+r+ H 
  EEA20575.1 189 ALAKHMRTvHE 199
                 699****6585 PP

>> zf-C2H2_6  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   0.8   8.3e-05      0.19      13      25 ..     156     168 ..     153     170 .. 0.89
   2 !   15.8   0.0   4.5e-06      0.01       6      25 ..     179     199 ..     178     201 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 8.3e-05
   zf-C2H2_6  13 slqaLggHkksHr 25 
                 s++aL+ H++sH 
  EEA20575.1 156 SGYALRAHMRSHT 168
                 9***********6 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 4.5e-06
   zf-C2H2_6   6 vCsksFpslqaLggHkks.Hr 25 
                 +C++sF   +aL +H+++ H+
  EEA20575.1 179 ECDRSFTRSDALAKHMRTvHE 199
                 9*****************555 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.4         1   2.3e+03      14      23 .]     122     132 ..     120     132 .. 0.82
   2 ?    2.0   4.1      0.15   3.3e+02       2      23 .]     141     167 ..     140     167 .. 0.64
   3 !   26.2   0.3   3.1e-09   7.1e-06       1      23 []     173     198 ..     173     198 .. 0.94

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 1
                 HHHHHHHHC.C CS
     zf-C2H2  14 snLkrHirt.H 23 
                 +nL++Hi   H
  EEA20575.1 122 DNLVNHIHDeH 132
                 79****98766 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.15
                 EET..TTT...EEESSHHHHHHHHHCC CS
     zf-C2H2   2 kCp..dCg...ksFkrksnLkrHirtH 23 
                  C+  dC+   ++  + + L++H+r+H
  EEA20575.1 141 SCEwtDCSrkgQTHASGYALRAHMRSH 167
                 5555566644444445588******99 PP

  == domain 3  score: 26.2 bits;  conditional E-value: 3.1e-09
                 EEET..TTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirt.H 23 
                 ++C   +C++sF+r++ L +H+rt H
  EEA20575.1 173 FYCAlpECDRSFTRSDALAKHMRTvH 198
                 788888******************99 PP

>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.3   1.5   9.3e-05      0.21       6      35 ..     107     137 ..     104     144 .. 0.82
   2 ?    1.3   0.5      0.24   5.4e+02       6      19 ..     141     154 ..     137     171 .. 0.66
   3 !   12.6   0.0   7.1e-05      0.16       7      32 ..     175     200 ..     173     209 .. 0.94

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 9.3e-05
     FOXP-CC   6 vCkWPgCek.vledveeflkhlnseHalddk 35 
                 +C+W gCe+  l +++++++h+++eH  + +
  EEA20575.1 107 ICRWDGCEAgDLGNMDNLVNHIHDEHIGTRQ 137
                 7******874699*************76665 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.24
     FOXP-CC   6 vCkWPgCekvledv 19 
                  C+W +C++  +++
  EEA20575.1 141 SCEWTDCSRKGQTH 154
                 7******7654443 PP

  == domain 3  score: 12.6 bits;  conditional E-value: 7.1e-05
     FOXP-CC   7 CkWPgCekvledveeflkhlnseHal 32 
                 C+ P+C++ ++ ++++ kh+++ H++
  EEA20575.1 175 CALPECDRSFTRSDALAKHMRTVHET 200
                 999*********************86 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.1       4.6     1e+04      12      24 .]     120     132 ..     107     132 .. 0.68
   2 !    6.5   0.5    0.0079        18       3      23 ..     142     167 ..     140     168 .. 0.78
   3 !   17.6   0.2   2.2e-06    0.0049       3      24 .]     175     198 ..     173     198 .. 0.86

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 4.6
   zf-C2H2_4  12 skkaLlrHlkthH 24 
                 + ++L +H+   H
  EEA20575.1 120 NMDNLVNHIHDEH 132
                 5567889986665 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0079
   zf-C2H2_4   3 Cpi..C...gksFsskkaLlrHlkth 23 
                 C++  C   g++  s +aL+ H+++h
  EEA20575.1 142 CEWtdCsrkGQTHASGYALRAHMRSH 167
                 666667776788889999*******9 PP

  == domain 3  score: 17.6 bits;  conditional E-value: 2.2e-06
   zf-C2H2_4   3 Cpi..CgksFsskkaLlrHlkthH 24 
                 C +  C++sF++++aL +H++t+H
  EEA20575.1 175 CALpeCDRSFTRSDALAKHMRTVH 198
                 55555******************9 PP

>> zf-C2H2_11  zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.1      0.75   1.7e+03      13      25 ..     153     165 ..     145     165 .. 0.79
   2 ?   10.1   0.0   0.00024      0.53       9      28 ..     179     198 ..     175     199 .. 0.96

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.75
  zf-C2H2_11  13 cftSqlsLsRHlf 25 
                   +S  +L+ H++
  EEA20575.1 153 THASGYALRAHMR 165
                 5789999****96 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00024
  zf-C2H2_11   9 eCGlcftSqlsLsRHlfIvH 28 
                 eC + ft + +L +H++ vH
  EEA20575.1 179 ECDRSFTRSDALAKHMRTVH 198
                 7******************* PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0         8   1.8e+04      14      21 ..     121     128 ..     120     128 .. 0.75
   2 ?    1.1   0.0      0.24   5.3e+02      15      24 ..     158     167 ..     155     167 .. 0.86
   3 ?    8.5   0.2    0.0011       2.6       5      23 ..     178     196 ..     172     198 .. 0.83

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 8
                  HHHHHCCT CS
  zf-C2H2_jaz  14 enaldnHl 21 
                  + +l nH+
   EEA20575.1 121 MDNLVNHI 128
                  567999*7 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.24
                  HHHHCCTTSH CS
  zf-C2H2_jaz  15 naldnHlkSK 24 
                  +al++H++S+
   EEA20575.1 158 YALRAHMRSH 167
                  589*****97 PP

  == domain 3  score: 8.5 bits;  conditional E-value: 0.0011
                  TTTTBBBSSHHHHHCCTTS CS
  zf-C2H2_jaz   5 vlCdKyFksenaldnHlkS 23 
                  ++Cd+ F  + al +H+++
   EEA20575.1 178 PECDRSFTRSDALAKHMRT 196
                  47***************96 PP

>> Zap1_zf2  Zap1 zinc finger 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   4.3    0.0016       3.5       1      24 []     108     132 ..     108     132 .. 0.85
   2 ?    6.8   1.1    0.0029       6.5       1      10 [.     142     151 ..     142     153 .. 0.84

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0016
    Zap1_zf2   1 CnWkDCdF.egeDicSLiNHINdkH 24 
                 C+W+ C+      ++ L+NHI d+H
  EEA20575.1 108 CRWDGCEAgDLGNMDNLVNHIHDEH 132
                 9999999874445999********9 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.0029
    Zap1_zf2   1 CnWkDCdFeg 10 
                 C+W+DC  +g
  EEA20575.1 142 CEWTDCSRKG 151
                 ******8666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (364 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       502  (0.0279993); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.49u 0.29s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 2403.74
//
Query:       EEA20576.1  [L=523]
Description: dimethylaniline monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.5e-62  211.8   0.0      3e-62  210.8   0.0    1.4  1  FMO-like        Flavin-binding monooxygenase-like
    1.7e-12   47.2   0.0    1.8e-10   40.6   0.0    2.3  2  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
      6e-11   42.1   0.8    3.5e-07   29.7   0.0    3.1  3  K_oxygenase     L-lysine 6-monooxygenase (NADPH-requiring)
    8.7e-08   32.3   0.0    2.2e-07   31.0   0.0    1.8  1  NAD_binding_8   NAD(P)-binding Rossmann-like domain
    1.3e-07   31.1   0.0    4.6e-07   29.4   0.0    1.7  2  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
      9e-06   25.8   0.0     0.0006   19.8   0.0    2.9  3  NAD_binding_9   FAD-NAD(P)-binding
    8.9e-05   22.9   0.0       0.21   12.1   0.0    2.4  2  NAD_binding_7   Putative NAD(P)-binding
    0.00018   21.6   0.1        1.9    8.6   0.0    3.1  3  Shikimate_DH    Shikimate / quinate 5-dehydrogenase
     0.0002   20.8   0.0       0.05   13.0   0.0    2.2  2  2-Hacid_dh_C    D-isomer specific 2-hydroxyacid dehydrogenase
    0.00021   21.8   0.1       0.02   15.4   0.0    2.7  2  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
    0.00029   20.2   0.6    0.00075   18.8   0.0    1.9  3  Thi4            Thi4 family
    0.00071   19.2   0.0      0.029   14.0   0.0    2.9  3  IlvN            Acetohydroxy acid isomeroreductase, NADPH-bin
     0.0022   17.5   0.2      0.013   15.0   0.0    2.2  3  Glu_dehyd_C     Glucose dehydrogenase C-terminus
     0.0037   16.9   0.0      0.064   12.8   0.0    2.3  2  DAO             FAD dependent oxidoreductase
     0.0044   16.3   0.0       0.19   11.0   0.0    2.4  2  Amino_oxidase   Flavin containing amine oxidoreductase
  ------ inclusion threshold ------
      0.011   15.9   0.0      0.027   14.6   0.0    1.6  1  NAD_binding_2   NAD binding domain of 6-phosphogluconate dehy
      0.016   15.2   0.1      0.035   14.1   0.1    1.6  1  NAD_Gly3P_dh_N  NAD-dependent glycerol-3-phosphate dehydrogen
      0.025   13.7   0.0      0.042   12.9   0.0    1.3  1  FAD_binding_2   FAD binding domain
      0.026   13.8   0.0      0.091   12.0   0.0    1.9  2  FAD_binding_3   FAD binding domain
      0.026   13.8   0.0      0.055   12.8   0.0    1.5  1  AlaDh_PNT_C     Alanine dehydrogenase/PNT, C-terminal domain
      0.086   11.5   0.0       0.14   10.8   0.0    1.3  1  HI0933_like     HI0933-like protein


Domain annotation for each model (and alignments):
>> FMO-like  Flavin-binding monooxygenase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  210.8   0.0   3.5e-65     3e-62       3     490 ..      13     517 ..      11     522 .. 0.82

  Alignments for each domain:
  == domain 1  score: 210.8 bits;  conditional E-value: 3.5e-65
    FMO-like   3 kvaviGaGvsGlasikccleegleptcfersddiGGlwrfkenveeGrasiyksvvsnsskemscfsdfplpedypnflhnsklleylklfakefdllk 101
                  vaviGaG sGl+ +k+  e+g++ tc+er  ++GGlw ++++ +   ++  k+  +n sk     sdfp+pe+yp +l + +++ +++ +a++f+ll 
  EEA20576.1  13 TVAVIGAGSSGLSMLKTLRENGFKVTCYERRSQVGGLWAWSDKKD--VTTALKTTTANISKYTCGMSDFPMPEEYPPHLTQAQFQSFMQSYAEHFNLLP 109
                 59**************************************99765..556689********************************************** PP

    FMO-like 102 yiqfkttvcsvkkrpdfstsGqwevvtekegkkesavfdavmvctGhhvnphlplesfpGiekfkGqyfhsrdykepevfkgkrvlviGlGnsggdiav 200
                  i f +++ +v ++    t  +w +  + +gk + + +d v    G+ +++++p+  f G ekf G ++h++++k+pe f++k+v+v+G+G ++gdi  
  EEA20576.1 110 DIVFDAKLEQVYRNE---TDSKWLLQLNINGKPRIEEYDKVAFTHGYQTKAKVPQ--FAGQEKFEGVLIHAQEFKSPEQFRDKKVIVVGIGSTAGDIIE 203
                 *********999875...4568********************************6..9***************************************** PP

    FMO-like 201 elsrtaeqvllstrsGswvlsrvsdsGypwdmllvtr...fksllknilptalsnwlvekk....lnkrfnh..enyglkpkkralakepvlndelpar 290
                  l   a ++++s r+G+ ++sr      p+d+l++ r   ++++l++++p+++  wl +      + +r+ +   ++ l p    l   p   + +  +
  EEA20576.1 204 TLLPVASKIYVSHRRGTAIISRWR-GDKPTDLLVSWRrrqISQFLTRNFPKTM-RWLSVAGtewlMKSRWGKlePEWNLLPFPSPLLVLPSASETVIPA 300
                 **********************65.568*****98652336789999999986.455544300003333322113456666666666666666666667 PP

    FMO-like 291 ilaGavkvkssvkelte.tsaifedgtveedidvvifatGytfafp...fleeslvkvekn.kv.slykkvfpanlekptlaiiGliqplGsilptvel 383
                 +  G ++    +k +   +s+ + dgtv +++d+vi atGyt +f    f+e s     +   v  l+k++fp++  ++   +      +   ++ +++
  EEA20576.1 301 LQNGSLTSLRGLKGFVGpKSIELIDGTVIHEVDAVICATGYTADFTvarFIETSQPAGPEGpSVrRLWKNIFPPKYANSIAMLCYSAYGKNNGFSFCDV 399
                 778888877778877651677799******************999655599999766554413327*********98875444444556778899**** PP

    FMO-like 384 qarwavrvlkGlkklpsekelleeitekkekkakrfg...esksktiqt.dyiayldela....aligakpnllslllkdpklalkvffGpcspyqyrl 474
                  +  + ++ + +  lp+++++ +ei e++  +++ +    + +s+++++ +y +++++ a    + +g   +   +++kdpk++  +  G  +++ +r 
  EEA20576.1 400 SSMAISNIWRDVHPLPTQEQMEKEIDEHHRWIVSNWEldhNIDSSMVKSwEYQSFVHDAAgtgmENLGWGWKGWKFFFKDPKMSYLMNNGVETAHAFRY 498
                 ***************************988776554311144566666448999999886333345777788899************************ PP

    FMO-like 475 vGpGk...weGarkailtq 490
                    Gk   w+Gar+ai+  
  EEA20576.1 499 FETGKrkvWPGAREAIIHA 517
                 99998888********865 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.6   0.0   2.1e-13   1.8e-10       2     197 ..      16     219 ..      15     262 .. 0.81
   2 ?    4.4   0.0     0.022        18     249     275 ..     323     349 ..     316     359 .. 0.82

  Alignments for each domain:
  == domain 1  score: 40.6 bits;  conditional E-value: 2.1e-13
  Pyr_redox_3   2 IiGaGPaGlaaaielkkagledylilEkgnignsiyrypkemtfispsftsekleipdlnaiseets..pafslkeeklsrkealeYlrevaksfel. 96 
                  +iGaG  Gl++  +l+++g+ +++  E+ + +  +  +  ++ + + + +++  +i +    + + s  p      ++l+++++ ++++++a++f+l 
   EEA20576.1  16 VIGAGSSGLSMLKTLRENGF-KVTCYERRSQVGGLWAWSDKKDVTT-ALKTTTANISKY---TCGMSdfPMPEEYPPHLTQAQFQSFMQSYAEHFNLl 108
                  8*******************.79***************99988855.555555555554...4444412444445679*******************7 PP

  Pyr_redox_3  97 .piklfeeVesvkkedeg......fevetsketyeAkkviiAtGefdkPnklnipGeek...lvkhyskvkefhkyagqkvvViGgknSavDaAlelv 184
                   +i  + + e+v ++++        +++ + +  e +kv    G+  k +++++ G+ek     +h +++k++++++++kv+V+G + +a D+   l 
   EEA20576.1 109 pDIVFDAKLEQVYRNETDskwllqLNINGKPRIEEYDKVAFTHGYQTKAKVPQFAGQEKfegVLIHAQEFKSPEQFRDKKVIVVGIGSTAGDIIETLL 206
                  77***********975432222113455555677889*********************8655578***************************999999 PP

  Pyr_redox_3 185 rkgaeVtvvtrgs 197
                     +++ v +r+ 
   EEA20576.1 207 PVASKIYVSHRRG 219
                  9989988888764 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.022
  Pyr_redox_3 249 tedgkkvevkddvvlatGykpdlsflk 275
                    dg+ +++ d v+ atGy+ d+++ +
   EEA20576.1 323 LIDGTVIHEVDAVICATGYTADFTVAR 349
                  5689999999************98754 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.5   0.0    0.0046       3.9     183     214 ..       3      34 ..       1      49 [. 0.76
   2 !   29.7   0.0   4.1e-10   3.5e-07      93     215 ..      89     210 ..      79     224 .. 0.86
   3 ?    2.7   0.1     0.064        55     328     341 ..     329     342 ..     324     343 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0046
  K_oxygenase 183 erkeellakkriaVvGsGqSaaeifedllrrq 214
                  +r+++l+++ ++aV+G+G S+  +++ l ++ 
   EEA20576.1   3 TRQANLNQPSTVAVIGAGSSGLSMLKTLRENG 34 
                  567789999************99998887663 PP

  == domain 2  score: 29.7 bits;  conditional E-value: 4.1e-10
  K_oxygenase  93 psRkefedYlrWvasqle..eqvrfgeeveevepdeeeeeelltveskdaegeeeelearnlvlgvG..tepkiPevleklegkervvHsseylerke 186
                  ++ ++f+++++  a++++    + f+++ e+v  +e +++ ll+++    +g+ +  e  ++  + G  t++k+P+++ + + +  ++H++e+ + + 
   EEA20576.1  89 LTQAQFQSFMQSYAEHFNllPDIVFDAKLEQVYRNETDSKWLLQLNI---NGKPRIEEYDKVAFTHGyqTKAKVPQFAGQEKFEGVLIHAQEFKSPE- 182
                  57889***********9966459*************99889999997...6777777777777777765999*******999999********9987. PP

  K_oxygenase 187 ellakkriaVvGsGqSaaeifedllrrqk 215
                   + + k+++VvG G +a++i+e ll  ++
   EEA20576.1 183 -QFRDKKVIVVGIGSTAGDIIETLLPVAS 210
                  .8999*****************9986654 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.064
  K_oxygenase 328 tlevdavvlATGYr 341
                   +evdav++ATGY+
   EEA20576.1 329 IHEVDAVICATGYT 342
                  689**********6 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.0   0.0   2.6e-10   2.2e-07       1      38 [.      16      53 ..      16      93 .. 0.77

  Alignments for each domain:
  == domain 1  score: 31.0 bits;  conditional E-value: 2.6e-10
                   EE--SHHHHHHHHHHHCCTEEEEEE-SSSSSSGGG-EE CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekrdrlGGraasy 38
                   ++GaG sGl++  +L+++gf+v+++e+r+++GG +a  
     EEA20576.1 16 VIGAGSSGLSMLKTLRENGFKVTCYERRSQVGGLWAWS 53
                   8*******************************987744 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.4   0.0   5.4e-10   4.6e-07       2     173 ..      13     217 ..      12     226 .. 0.67
   2 ?   -1.3   0.0       1.2     1e+03     221     240 ..     324     344 ..     311     354 .. 0.75

  Alignments for each domain:
  == domain 1  score: 29.4 bits;  conditional E-value: 5.4e-10
                  SEEEE--SHHHHHHHHHHHHHTS-EEEEE................TTHCHHHCSHHHHCHHHHHHHHHHHHH.......HHHHCHHHHCCCCHC.CTC CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxx................xxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxxx.xxx RF
  Pyr_redox_2   2 dvvviGgGpAGlaaaltlaqagakvtlve................legtclnggcllskallgvaedaeias.......evvkklnqgielllg.eev 75 
                   v+viG+G  Gl++ +tl+++g+kvt++e                 ++++ + +  +sk  +g+++++  ++        +++++ q++    +  + 
   EEA20576.1  13 TVAVIGAGSSGLSMLKTLRENGFKVTCYErrsqvgglwawsdkkdVTTALKTTTANISKYTCGMSDFPMPEEypphltqAQFQSFMQSYAEHFNlLPD 110
                  59**************************6555555555555554333333344444466666666666555599999985555555554444442112 PP

                  EEEEESCEEEEETEEEC.........TCEEEEEESEEEE---E..EE-BCTCTTC.TTBEECCSECHHHHHHCCSS-T..SEEEEES-SHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxx.........xxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  76 vkidpgkkkvklekkke.........gdeekiaydklvlAtGs..sprdlgipGvaenvgklvrtldsaealklkllp..krivvvGgGyiGvElAaa 160
                  + +d + ++v  +++++         g+ +  +ydk+    G   +++ ++  G ++    +   l +a+++k+ ++   k+++vvG G ++ ++  +
   EEA20576.1 111 IVFDAKLEQVYRNETDSkwllqlninGKPRIEEYDKVAFTHGYqtKAKVPQFAGQEKFE--G--VLIHAQEFKSPEQFrdKKVIVVGIGSTAGDIIET 204
                  33333334455544444688888887999999**********63466666777884444..3..56777777766555569********999888888 PP

                  HHHHT-EEEEEES CS
                  xxxxxxxxxxxxx RF
  Pyr_redox_2 161 laklgkevtlvea 173
                  l  +++++++ ++
   EEA20576.1 205 LLPVASKIYVSHR 217
                  8777777776665 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.2
                  TTSCE.EEESEEEE-S-EEES CS
                  xxxxx.xxxxxxxxxxxxxxx RF
  Pyr_redox_2 221 edgee.idadlvvvavGvrps 240
                   dg++  ++d v+ a+G++++
   EEA20576.1 324 IDGTViHEVDAVICATGYTAD 344
                  566664589999999999887 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.0     7e-07    0.0006       1      66 [.      15      76 ..      15     131 .. 0.84
   2 ?    2.0   0.0      0.21   1.8e+02       2      77 ..     191     262 ..     190     277 .. 0.82
   3 ?   -0.6   0.0       1.3   1.1e+03     138     155 ..     323     341 ..     313     342 .. 0.80

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 7e-07
  NAD_binding_9  1 aivGaGprGlavlerLlarakkkspleitlfdp.sepgagrvwrtdqseelllNvpasemslftddp 66
                   a++GaG +Gl++l+ L ++      +++t++++ s+ g  ++w+++++ +  l ++++++s +t   
     EEA20576.1 15 AVIGAGSSGLSMLKTLREN-----GFKVTCYERrSQVGGLWAWSDKKDVTTALKTTTANISKYTCGM 76
                   89**************999.....6********66778899*****999999999999999776555 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.21
  NAD_binding_9   2 ivGaGprGlavlerLlarakkkspleitlfdpsepgagrvwrtdqseelllNvpasemslftddp.ptfaeWlrerg 77 
                    +vG G ++  ++e Ll  a      +i +  ++++   + wr d+++ ll+  + +++s f  ++ p+  +Wl+  g
     EEA20576.1 191 VVGIGSTAGDIIETLLPVA-----SKIYVSHRRGTAIISRWRGDKPTDLLVSWRRRQISQFLTRNfPKTMRWLSVAG 262
                    7888888888888888775.....7899999988866899*******************999888888889987765 PP

  == domain 3  score: -0.6 bits;  conditional E-value: 1.3
  NAD_binding_9 138 ladgasl.aadaVvLAlGh 155
                    l dg+ + ++daV+ A+G 
     EEA20576.1 323 LIDGTVIhEVDAVICATGY 341
                    567776559********96 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.6   0.0     0.003       2.6       8      39 ..      12      43 ..       9     120 .. 0.82
   2 !   12.1   0.0   0.00024      0.21       4      55 ..     183     243 ..     182     343 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.003
  NAD_binding_7  8 kkvlvvGgGevAarkvrklleagakvtvvape 39
                    +v v+G+G+ +++ +++l e+g kvt +  +
     EEA20576.1 12 STVAVIGAGSSGLSMLKTLRENGFKVTCYERR 43
                   5899***********************98877 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 0.00024
  NAD_binding_7   4 dlkgkkvlvvGgGevAarkvrklleagakvtvvapevkeele.........elvklaeeel 55 
                    ++++kkv+vvG G+ A   +++ll+   k+ v   + +++++          lv+++++++
     EEA20576.1 183 QFRDKKVIVVGIGSTAGDIIETLLPVASKIYVSHRRGTAIISrwrgdkptdLLVSWRRRQI 243
                    799***********************99999966555333334444444446666777664 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.4   0.0    0.0025       2.1      10      45 ..       9      43 ..       1      58 [. 0.84
   2 !    8.6   0.0    0.0022       1.9       8      44 ..     182     217 ..     174     225 .. 0.80
   3 ?    0.5   0.0      0.69   5.9e+02      71      86 ..     327     342 ..     320     357 .. 0.84

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0025
                  .TT-EEEEES-SHHHHHHHHHHHCCT-CEEEEEESS CS
  Shikimate_DH 10 lkekkvlliGaGemaelvakhLlakgvkkvvvaNRt 45
                   + ++v +iGaG  +  ++k L ++g+k v+   R 
    EEA20576.1  9 NQPSTVAVIGAGSSGLSMLKTLRENGFK-VTCYERR 43
                  45679*********************99.8877775 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.0022
                   S..TT-EEEEES-SHHHHHHHHHHHCCT-CEEEEEES CS
  Shikimate_DH   8 eslkekkvlliGaGemaelvakhLlakgvkkvvvaNR 44 
                   e++++kkv+++G G +a  +++ Ll   + k+ v  R
    EEA20576.1 182 EQFRDKKVIVVGIGSTAGDIIETLLPV-ASKIYVSHR 217
                   4899********************954.444777665 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.69
                   HHHHT-SEEEE-SSSS CS
  Shikimate_DH  71 ellaeadvvisatase 86 
                   ++++e+d vi+at+ +
    EEA20576.1 327 TVIHEVDAVICATGYT 342
                   5799*********865 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.0   0.0   5.8e-05      0.05      35      70 ..      10      45 ..       2      67 .. 0.86
   2 ?    5.5   0.0     0.012        10      25      69 ..     175     219 ..     155     234 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 5.8e-05
                  TTSEEEEES-SHHHHHHHHHHHHTT-EEEEESSSHH CS
  2-Hacid_dh_C 35 sgktvGiiGlGrIGqavakrlkafgmkviaydrskk 70
                  + +tv++iG+G+ G ++ k+l++ g+kv++y+r+ +
    EEA20576.1 10 QPSTVAVIGAGSSGLSMLKTLRENGFKVTCYERRSQ 45
                  568*****************************9976 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.012
                   TTCCGSBS-GTTSEEEEES-SHHHHHHHHHHHHTT-EEEEESSSH CS
  2-Hacid_dh_C  25 sekallgkelsgktvGiiGlGrIGqavakrlkafgmkviaydrsk 69 
                   +++  + ++ ++k+v ++G+G+ +  ++++l ++  k+++  r+ 
    EEA20576.1 175 AQEFKSPEQFRDKKVIVVGIGSTAGDIIETLLPVASKIYVSHRRG 219
                   5566677899************************99999988775 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   2.3e-05      0.02       2      35 ..      14      47 ..      13      68 .. 0.93
   2 ?    3.6   0.1      0.12     1e+02       1      33 [.     188     220 ..     188     230 .. 0.91

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 2.3e-05
                EEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSS CS
   Pyr_redox  2 vvvvGgGyiglElAgalaelgkkVtvversdkll 35
                v+v+G+G +gl + ++l+e g kVt+ er++++ 
  EEA20576.1 14 VAVIGAGSSGLSMLKTLRENGFKVTCYERRSQVG 47
                89*****************************987 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.12
                 EEEEECSSHHHHHHHHHHHHTTSEEEEEESSSS CS
   Pyr_redox   1 kvvvvGgGyiglElAgalaelgkkVtvversdk 33 
                 kv+vvG G ++ +  ++l   ++k++v +r+ +
  EEA20576.1 188 KVIVVGIGSTAGDIIETLLPVASKIYVSHRRGT 220
                 79****************************976 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.0   8.7e-07   0.00075      18      58 ..      12      50 ..       6      55 .. 0.88
   2 ?   -2.5   0.0       2.8   2.4e+03       9      28 ..     178     197 ..     173     202 .. 0.80
   3 ?   -3.9   0.1       7.8   6.7e+03     158     173 ..     331     346 ..     323     352 .. 0.67

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 8.7e-07
                EEEEEE--SHHHHHHHHHHHHCTTS-EEEEESSSS--TTTT CS
        Thi4 18 sDvvivGaGssGLtaayylakkpdlkvailersvspGGGaw 58
                s v+++GaGssGL+  ++l ++ ++kv+  er+  +GG  w
  EEA20576.1 12 STVAVIGAGSSGLSMLKTLREN-GFKVTCYERRSQVGG-LW 50
                6799******************.*********977765.55 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 2.8
                 HHHHHHHTEEEEEEE--SHH CS
        Thi4   9 fedllkyaesDvvivGaGss 28 
                 f+   ++ +  v++vG Gs+
  EEA20576.1 178 FKSPEQFRDKKVIVVGIGST 197
                 66667889999*****9985 PP

  == domain 3  score: -3.9 bits;  conditional E-value: 7.8
                 EEEEEEE--GSSSTTT CS
        Thi4 158 rakvvvdatGhdgeiv 173
                 +  +v+ atG+ +++ 
  EEA20576.1 331 EVDAVICATGYTADFT 346
                 4568888888888764 PP

>> IlvN  Acetohydroxy acid isomeroreductase, NADPH-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.0   0.0   3.3e-05     0.029       5      38 ..      12      45 ..       9     108 .. 0.81
   2 ?   -0.7   0.0       1.1   9.5e+02      82     100 ..     138     156 ..     127     169 .. 0.86
   3 ?    1.1   0.0       0.3   2.6e+02       3      18 ..     185     200 ..     183     227 .. 0.72

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 3.3e-05
                S-EEEES-SHHHHHHHHHHHHTT--EEEEE-TT- CS
        IlvN  5 kkiaviGyGsqGhaqalnlrdsgldvvvglregs 38
                 ++aviG Gs G +  + lr++g++v+   r+++
  EEA20576.1 12 STVAVIGAGSSGLSMLKTLRENGFKVTCYERRSQ 45
                58************************98887776 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 1.1
                 GGG--TT-EEEESSSHHHH CS
        IlvN  82 epnlkegkalafahGfnih 100
                 +p ++e + +af+hG++ +
  EEA20576.1 138 KPRIEEYDKVAFTHGYQTK 156
                 57899999********876 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.3
                 HTS-EEEES-SHHHHH CS
        IlvN   3 kgkkiaviGyGsqGha 18 
                 ++kk+ v+G Gs +  
  EEA20576.1 185 RDKKVIVVGIGSTAGD 200
                 79*********97655 PP

>> Glu_dehyd_C  Glucose dehydrogenase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   1.5e-05     0.013      22      68 ..       2      45 ..       1      51 [. 0.89
   2 ?   -2.9   0.0       4.6   3.9e+03      19      41 ..     174     196 ..     172     217 .. 0.83
   3 ?   -1.1   0.0       1.3   1.1e+03      97     113 ..     328     344 ..     320     358 .. 0.77

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.5e-05
  Glu_dehyd_C 22 asrsafewepesalvlGaGslGLLalalleaeerglervyvlgrrdr 68
                 a+r+a   +p+++ v+GaGs GL +l +l+   +g++ v++ +rr++
   EEA20576.1  2 ATRQANLNQPSTVAVIGAGSSGLSMLKTLRE--NGFK-VTCYERRSQ 45
                 67888889*********************95..8997.99***9976 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 4.6
  Glu_dehyd_C  19 laeasrsafewepesalvlGaGs 41 
                  +a++ +s  +++ ++++v+G Gs
   EEA20576.1 174 HAQEFKSPEQFRDKKVIVVGIGS 196
                  67778888899999999999997 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 1.3
  Glu_dehyd_C  97 aseemdlvvEaTGsakh 113
                  + +e+d v+ aTG+++ 
   EEA20576.1 328 VIHEVDAVICATGYTAD 344
                  56789********9874 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.8   0.0   7.4e-05     0.064       2      33 ..      14      47 ..      13      56 .. 0.91
   2 ?    1.2   0.0      0.26   2.2e+02     188     209 ..     326     349 ..     305     369 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 7.4e-05
                EEEECTSHHHHHHHHHHHHTT..EEEEESSSSTT CS
         DAO  2 vviiGGGiiGlstAyeLarrg..Vtllekgdiag 33
                v++iG+G  Gls    L + g  Vt +e+++++g
  EEA20576.1 14 VAVIGAGSSGLSMLKTLRENGfkVTCYERRSQVG 47
                99***************8889*********9998 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.26
                 EEE.EEEEEEEE--GGGHHHH.HT CS
         DAO 188 gen.daadavVnaaGawsdll.gl 209
                 g++ +++dav+ a+G  +d++ ++
  EEA20576.1 326 GTViHEVDAVICATGYTADFTvAR 349
                 4555679********999865444 PP

>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.0   0.00022      0.19       2      33 ..      22      54 ..      21      67 .. 0.85
   2 ?    2.7   0.0     0.073        62     243     261 ..     321     340 ..     313     379 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00022
                   HHHHHHHHHHHTTEEEEEEESSSSSBT.TS-EE CS
  Amino_oxidase  2 aGLaaArqLlsaGfdVtvlEardrvGG.Rirtv 33
                   +GL+  ++L ++Gf+Vt +E r++vGG +++++
     EEA20576.1 22 SGLSMLKTLRENGFKVTCYERRSQVGGlWAWSD 54
                   899999*********************334444 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.073
                    EEETTSTEE.EESEEEE-S- CS
  Amino_oxidase 243 vtledgevv.eaDaVvvTvp 261
                    ++l dg+v+ e+DaV++++ 
     EEA20576.1 321 IELIDGTVIhEVDAVICATG 340
                    6789*************986 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.0   3.2e-05     0.027       2      33 ..      14      45 ..      13      70 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 3.2e-05
                   EEEE--SHHHHHHHHHHHHTT-EEEEE-SSHH CS
  NAD_binding_2  2 igfiGlGvMGsnmalnllkagykvavynrtke 33
                   +++iG G  G +m + l ++g+kv++y+r+++
     EEA20576.1 14 VAVIGAGSSGLSMLKTLRENGFKVTCYERRSQ 45
                   89**************************9865 PP

>> NAD_Gly3P_dh_N  NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.1   4.1e-05     0.035       2      43 ..      14      67 ..      13      78 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 4.1e-05
                    EEEE--SHHHHHHHHHHHTTT--EEEE-S-H............HHHHHHHHHSS CS
  NAD_Gly3P_dh_N  2 iavlGaGswGtalAkvlaenghevrlwvree............elieeineehe 43
                    +av+GaGs G ++ k+l eng +v+ + r++            +++++++++  
      EEA20576.1 14 VAVIGAGSSGLSMLKTLRENGFKVTCYERRSqvgglwawsdkkDVTTALKTTTA 67
                    9********************999999999856555555555555555555555 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   4.9e-05     0.042       2      41 ..      14      53 ..      13      55 .. 0.96

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 4.9e-05
                   EEEE--SHHHHHHHHHHHHTTT-EEEEESSSGGGSGGGG- CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGlkvavvekeqefggataws 41
                   v ViG+G +GL+   +++e+G kv++ e  +++gg  aws
     EEA20576.1 14 VAVIGAGSSGLSMLKTLRENGFKVTCYERRSQVGGLWAWS 53
                   89*********************************99998 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   0.00011     0.091       3      35 ..      13      45 ..      11      47 .. 0.94
   2 ?   -2.3   0.0       2.4   2.1e+03      84     123 ..     145     185 ..     111     194 .. 0.61

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00011
                   EEEEE--SHHHHHHHHHHHHTTHHEEEEESSSS CS
  FAD_binding_3  3 dVlIVGaGpaGlmlallLseaGvrvvlvekrst 35
                   +V+++GaG +Gl+  + L+e G +v++ e+rs+
     EEA20576.1 13 TVAVIGAGSSGLSMLKTLRENGFKVTCYERRSQ 45
                   79***************************9985 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 2.4
                    CEEEEEHHCHHCST-CEE--HHHHHHHHHHHHHHHT.EEET CS
  FAD_binding_3  84 pkaradlelesspervtvypqteleriLvehaeerg.lqvr 123
                     k+   +  +++++ ++  +q+++e +L+++ e +   q+r
     EEA20576.1 145 DKVAFTHGYQTKAKVPQFAGQEKFEGVLIHAQEFKSpEQFR 185
                    33333333678889999999999999999887655445555 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   6.4e-05     0.055      27      65 ..      10      48 ..       2      79 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 6.4e-05
                 ---EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHHHHH CS
  AlaDh_PNT_C 27 epakvlviGgGvaGlqAiatakglgakVtvlDvrparle 65
                 +p++v viG+G  Gl+ ++t ++ g kVt ++ r+++  
   EEA20576.1 10 QPSTVAVIGAGSSGLSMLKTLRENGFKVTCYERRSQVGG 48
                 799*****************************9998765 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00016      0.14       2      36 ..      13      47 ..      12      53 .. 0.94

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00016
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SSSSS- CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVlllekakklg 36
                 +v+viG+G +Gl    +++++g +V+ +e+ +++g
   EEA20576.1 13 TVAVIGAGSSGLSMLKTLRENGFKVTCYERRSQVG 47
                 69****************************99988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (523 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       581  (0.0324056); expected 358.6 (0.02)
Passed bias filter:                      517  (0.028836); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                        21  (0.00117129); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              21  [number of targets reported over threshold]
# CPU time: 0.64u 0.28s 00:00:00.92 Elapsed: 00:00:00.43
# Mc/sec: 3631.54
//
Query:       EEA20577.1  [L=321]
Description: pyridoxal reductase (AKR8), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-63  214.8   0.0    1.8e-63  214.5   0.0    1.0  1  Aldo_ket_red  Aldo/keto reductase family


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  214.5   0.0   9.8e-68   1.8e-63       3     293 ..      13     311 ..      12     312 .. 0.95

  Alignments for each domain:
  == domain 1  score: 214.5 bits;  conditional E-value: 9.8e-68
                   EEE-SSS-ST..TS-HHHHHHHHHHHHHTT--EEE--TT-..TTTHHHHHHHHHHHH-TTTGGG-EEEEEE--SSSTTSSSS-HHHHHHHHHHHHHH CS
  Aldo_ket_red   3 glGtwqlgsk.eeiskeealellrraleaGinffDtAevY..gkgqseellGealkksrkkreeviiatKvdlrdaeiksglskeniresleeslkr 96 
                   g+Gt+++++   + ske+ le+l++ale G nf++ +e+Y      s +ll+ +++k++++ ++v++++K++  ++  ++++s+enir+s+++ lk 
    EEA20577.1  13 GYGTMRMTWNpIPPSKETCLETLNTALELGANFWNGGEIYgtSSYNSCHLLQAYFEKYPQNADKVVLSIKGGTVKDGLQPDGSEENIRRSVDDCLKV 109
                   89*******999999*************************33334556667777777**************************************** PP

                   HT-.S-EEEEEE-S--TTS-.HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHHHHTTT--EEEEE-B-BTT.-HHHHTTHHHHHHHTT-EEEEBST CS
  Aldo_ket_red  97 Lgt.dyvDllllHrpdpslpsieevldaleelvkeGkiraiGvSnfsveqlekakkkkkvkivavqveynll.releeegllelckkkgvpliaysp 191
                   L+  +++D+++++r dp++  +e ++ +l++l++eGki +iG+S++++e +++a  +k+++i+av+ve +l+  ++ e+ ++++c+++ +p+iaysp
    EEA20577.1 110 LKGtKKIDIFECARQDPNTT-VEQTVTILAKLIEEGKIGGIGLSEVDAETIRRA--HKVHPISAVEVELSLWsLDILENDVAKTCAELSIPVIAYSP 203
                   *987****************.*******************************99..****************99*********************** PP

                   TGGGTTGTTTSS---SSSCCC-------..TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTS.....TT-SEEEE--SSHHHHHHHHGGGG--- CS
  Aldo_ket_red 192 lggGlltgkyqseedkedkeprkdlkrd..ertsknldaaeelselakehgvslaqlalryalsq.....pavgivipgasnieqlednldalelkl 281
                   lg+G++tg+  + +d ++++ r++  ++   +++ nl+++ e+ +lak+++v +aq+al+++ s       +++i+ipg ++ +++++n++ +  +l
    EEA20577.1 204 LGRGAFTGEIANLADIPKGDFRRHVPKFqdGNYEHNLKLIHEVVDLAKKKNVAPAQIALAWVRSLsnktgLPTIIPIPGGTTKDKVTQNMQGV-ETL 299
                   *************************99999********************************9885555559*******************99.89* PP

                   -HHHHHHHHHHH CS
  Aldo_ket_red 282 seeevaeldell 293
                   ++ee+ae+d+ll
    EEA20577.1 300 TDEEMAEIDALL 311
                   *********986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (321 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       579  (0.032294); expected 358.6 (0.02)
Passed bias filter:                      541  (0.0301746); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.21s 00:00:00.67 Elapsed: 00:00:00.37
# Mc/sec: 2624.34
//
Query:       EEA20578.1  [L=429]
Description: hypothetical protein PMAA_044110 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
       0.29   11.7   0.2       0.29   11.7   0.2    3.4  3  Ribosomal_60s    60s Acidic ribosomal protein
       0.54   10.1  12.0        2.4    8.0   1.4    2.5  2  TLP-20           Nucleopolyhedrovirus telokin-like protein-20
          1    9.1  15.2       0.76    9.4   1.1    2.4  2  FAM176           FAM176 family
        2.2    6.4  23.0       0.35    9.0   9.1    2.1  2  Nop14            Nop14-like family
        3.8    7.2  27.5        0.2   11.4   7.8    2.2  2  Cwf_Cwc_15       Cwf15/Cwc15 cell cycle control protein
        5.5    7.0  16.9        3.2    7.7   2.2    2.5  2  RXT2_N           RXT2-like, N-terminal
        9.8    7.1  20.2        6.7    7.7   7.9    2.7  2  WRNPLPNID        Putative WW-binding domain and destruction b


Domain annotation for each model (and alignments):
>> Ribosomal_60s  60s Acidic ribosomal protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.2   0.00011      0.29      17      81 ..      46     113 ..      42     120 .. 0.66
   2 ?    6.6   2.9    0.0045        11      39      82 ..     177     222 ..     169     226 .. 0.51
   3 ?   -0.5   0.9      0.77     2e+03      48      64 ..     368     384 ..     344     390 .. 0.53

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00011
                    XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....XX--S CS
  Ribosomal_60s  17 eveaarvkllvkalegkdieellangaaklaaaaaaaaaaaaaaaaaaaaeekkkeeeee...Eeedd 81 
                    +ve +  +l+++  +++di+e ++++++k+a aaa   +++  ++   + ++  k ++     E++dd
     EEA20578.1  46 DVEGYLKQLDYEIPNNRDIQEWVKKVKKKGALAAAGELSGQHHDEDGHDHDQHTKSAPRPddnEHDDD 113
                    5778888999*******************764444444555555444444444444444467643333 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0045
                    XXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXXXXXX.XX--SS CS
  Ribosomal_60s  39 langaakla..aaaaaaaaaaaaaaaaaaaeekkkeeeeeEeeddd 82 
                    ++n  ++++  +++ a+++    +   ++++e+ ++ e e+e+d+d
     EEA20578.1 177 IKNNMNGMQpaQSVQASQSETNTDVLNPQQAEETEDDEDEDEDDED 222
                    6666667663333444444444444445555555555543333333 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 0.77
                    XXXXXXXXXXXXXXXXX CS
  Ribosomal_60s  48 aaaaaaaaaaaaaaaaa 64 
                     ++a + aa a+  a++
     EEA20578.1 368 VVTATPDAADAPMTAEQ 384
                    33333444444333333 PP

>> TLP-20  Nucleopolyhedrovirus telokin-like protein-20 (TLP20)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   1.4   0.00095       2.4     109     147 ..      91     126 ..      57     146 .. 0.73
   2 ?    6.7   3.3    0.0024       6.1     110     150 ..     191     230 ..     155     245 .. 0.72

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00095
      TLP-20 109 kksansklflsapveksssededdeddededeaakiesn 147
                 + + + ++ +sap + ++++d dd+dd   de+ +++s+
  EEA20578.1  91 DGHDHDQHTKSAPRPDDNEHDDDDDDD---DEDHHMNSG 126
                 567788999999987666665555555...444444443 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0024
      TLP-20 110 ksansklflsapveksssededdeddededeaakiesnsds 150
                 + ++s+ + ++  +++ +e+edded+ ded++++ + ++d+
  EEA20578.1 191 QASQSETNTDVLNPQQAEETEDDEDE-DEDDEDGEHGDHDE 230
                 44566677777778888888888888.55555444444333 PP

>> FAM176  FAM176 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   1.1    0.0003      0.76      55     105 ..      97     150 ..      76     155 .. 0.43
   2 ?    4.3   7.1     0.012        30      59      87 ..     204     231 ..     184     263 .. 0.55

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0003
      FAM176  55 kkkkkklkeesekasededeeeeeeeedsseseaeeel.......sefertlsvnvft 105
                 +++k+  +++++++++d+d+++e+++ +s +++            s ++ t sv++ft
  EEA20578.1  97 QHTKSAPRPDDNEHDDDDDDDDEDHHMNSGDAA----PpfqvarpSGSRATHSVSTFT 150
                 222222222222222222222222222222222....123445555555555666666 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.012
      FAM176  59 kklkeesekasededeeeeeeeedssese 87 
                  +++ee+ +++edede++e+ e+ +++++
  EEA20578.1 204 PQQAEET-EDDEDEDEDDEDGEHGDHDEH 231
                 2222222.233333333333333333333 PP

>> Nop14  Nop14-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   6.0    0.0079        20     343     387 ..      79     122 ..      52     138 .. 0.47
   2 ?    9.0   9.1   0.00014      0.35     337     414 ..     174     251 ..     164     291 .. 0.39

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.0079
       Nop14 343 taeeeeeededdfeedddlveseseeeeeeeeedeeeeedeeeee 387
                  a e++ +  d++ +d+d+  + s   ++++e d+++++d+e+ +
  EEA20578.1  79 AAGELSGQHHDEDGHDHDQHTK-SAPRPDDNEHDDDDDDDDEDHH 122
                 2333444444444444433333.3323334444444444444333 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00014
       Nop14 337 gkglka....taeeeeeededdfeedddlveseseeeeeeeeedeeeeedeeeeeeeeededdlsdleseeeeeedeleeel 414
                 g+g+k+     ++ ++++ ++++++ d l+ ++ e  e e++ede+e++++ e  +++e  d++++ +   +e  d+ e++ 
  EEA20578.1 174 GDGIKNnmngMQPAQSVQASQSETNTDVLNPQQAE--ETEDDEDEDEDDEDGEHGDHDEHGDHAKHGD--HDEHGDHGEHGV 251
                 45553323332222222222222222222222222..2222222222222222222222222222222..222333333332 PP

>> Cwf_Cwc_15  Cwf15/Cwc15 cell cycle control protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   7.8   7.7e-05       0.2     101     144 ..      73     120 ..      36     125 .. 0.47
   2 ?    1.6  11.8     0.076   1.9e+02      97     125 ..     194     224 ..     165     256 .. 0.36

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 7.7e-05
                 -------.......----------------------------------- CS
  Cwf_Cwc_15 101 keelleea.....reidaddedseeeeeeeeeesdddsdsdsddddded 144
                 k+ +l+ a     ++ d+d +d+++++++   + dd++ +d+ddddded
  EEA20578.1  73 KKGALAAAgelsgQHHDEDGHDHDQHTKS-APRPDDNEHDDDDDDDDED 120
                 22234443111112334444444332222.2333333333333333343 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.076
                 -----------....---------------- CS
  Cwf_Cwc_15  97 akrrkeelleea..reidaddedseeeeeee 125
                 + ++++++l+ +  +e ++d++++e++e+ e
  EEA20578.1 194 QSETNTDVLNPQqaEETEDDEDEDEDDEDGE 224
                 1111111221110012222222222111111 PP

>> RXT2_N  RXT2-like, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   2.2    0.0013       3.2      54      84 ..      82     123 ..      35     135 .. 0.56
   2 ?    4.3   7.0     0.014        36      58      83 ..     205     236 ..     176     264 .. 0.44

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0013
      RXT2_N  54 k..........kekekeekeeeeedeegdeededdddee.ea 84 
                 +          +++++++k++   d++++++d+dddde+ + 
  EEA20578.1  82 ElsgqhhdedgHDHDQHTKSAPRPDDNEHDDDDDDDDEDhHM 123
                 044444455554444545555454555544444444433232 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.014
      RXT2_N  58 ekeekeeeeedeegdeededdddee......e 83 
                 +++e++e++ede++d+ed + +d++      +
  EEA20578.1 205 QQAEETEDDEDEDEDDEDGEHGDHDehgdhaK 236
                 11112222222222222222221112233232 PP

>> WRNPLPNID  Putative WW-binding domain and destruction box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   4.4     0.027        70      35      63 ..      91     120 ..      72     125 .. 0.57
   2 ?    7.7   7.9    0.0026       6.7      22      62 ..     183     224 ..     177     228 .. 0.73

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.027
   WRNPLPNID  35 egesvdedeeaeee.......eeeeeeeedeedsgf 63 
                 +g+  d d+            +++e +++d++d+++
  EEA20578.1  91 DGH--DHDQ----HtksaprpDDNEHDDDDDDDDED 120
                 222..1111....12234556777777777777765 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0026
   WRNPLPNID  22 eLllldseaeessege.svdedeeaeeeeeeeeeeedeedsg 62 
                 +++  +s++ ++se++  v ++++aee e++e+e+ed+ed++
  EEA20578.1 183 GMQPAQSVQASQSETNtDVLNPQQAEETEDDEDEDEDDEDGE 224
                 556556666666667777788888888899999999888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (429 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       868  (0.0484132); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        88  (0.00490825); expected 17.9 (0.001)
Passed Fwd filter:                        51  (0.00284455); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.75u 0.30s 00:00:01.05 Elapsed: 00:00:00.46
# Mc/sec: 2830.97
//
Query:       EEA20579.1  [L=449]
Description: adenosylhomocysteinase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.7e-128  428.0   0.0    9.9e-74  248.2   0.1    2.0  2  AdoHcyase      S-adenosyl-L-homocysteine hydrolase
    1.4e-82  275.5   3.2    2.3e-82  274.8   3.2    1.3  1  AdoHcyase_NAD  S-adenosyl-L-homocysteine hydrolase, NAD bindi
    4.9e-07   29.3   0.1      1e-06   28.2   0.1    1.5  1  2-Hacid_dh_C   D-isomer specific 2-hydroxyacid dehydrogenase,
     0.0023   17.5   0.2     0.0045   16.6   0.2    1.4  1  IlvN           Acetohydroxy acid isomeroreductase, NADPH-bind
  ------ inclusion threshold ------
       0.01   15.6   0.1      0.017   14.8   0.1    1.4  1  ELFV_dehydrog  Glutamate/Leucine/Phenylalanine/Valine dehydro
      0.014   15.6   0.1      0.033   14.5   0.1    1.6  1  TrkA_N         TrkA-N domain
      0.034   14.0   0.8      0.061   13.2   0.8    1.4  1  3HCDH_N        3-hydroxyacyl-CoA dehydrogenase, NAD binding d
       0.14   12.6   0.3       0.44   11.0   0.3    1.9  2  NAD_binding_7  Putative NAD(P)-binding


Domain annotation for each model (and alignments):
>> AdoHcyase  S-adenosyl-L-homocysteine hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  248.2   0.1   4.4e-77   9.9e-74       2     139 ..       8     145 ..       7     149 .. 0.98
   2 !  180.4   0.0   1.9e-56   4.3e-53     171     299 .]     144     448 ..     143     448 .. 0.96

  Alignments for each domain:
  == domain 1  score: 248.2 bits;  conditional E-value: 4.4e-77
                 -B-S-GGGHHHHHHHHHHHHCC-HHHHHHHHHCTTT-TTTT-EEEEES--SHHHHHHHHHHHHTT-EEEEE-SSTTT--HHHHHHHCCTTEEEE--TT- CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   AdoHcyase   2 ykvkdislaefGrkeielaekempglmalreeyaeekplkgariaGslhmtiqtavLietLvalGaevrWasCnifstqdeaaaaiaeagvpvfawkge 100
                 +kv+disla+fGr+eielae empglma+r++ya+++pl+g riaG+lhmtiqtavLietL+alGaev+W+sCnifstqd+aaaaia++gvpvfawkge
  EEA20579.1   8 FKVADISLAAFGRREIELAEVEMPGLMAIRAKYAADQPLAGSRIAGCLHMTIQTAVLIETLTALGAEVTWTSCNIFSTQDHAAAAIAASGVPVFAWKGE 106
                 9************************************************************************************************** PP

                 -HHHHHHHHHHCHS-SSTS-S-SEEEESSSHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   AdoHcyase 101 tleeywwcieqalkwaedekepnlilDdGGDltllvhkg 139
                 t+eey wc+eq+l+  +d+k+ nlilDdGGDlt lvhk 
  EEA20579.1 107 TEEEYEWCLEQQLNAFKDGKKLNLILDDGGDLTSLVHKK 145
                 *************************************94 PP

  == domain 2  score: 180.4 bits;  conditional E-value: 1.9e-56
                 THHCCCHCC--EEEE-SHHHHHHHHHHHHTT---SEEEESTTSHHHCTTH................................................. CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................................................. RF
   AdoHcyase 171 kkytellkkikGvseetttGvhrLyelakkgkLlvpainvndsvtkskfD................................................. 220
                 kky+e lk++ GvseetttGvh+Ly++ k+gkLlvpainvndsvtkskfD                                                 
  EEA20579.1 144 KKYPEQLKDCYGVSEETTTGVHHLYRMLKEGKLLVPAINVNDSVTKSKFDnlygcreslidgikratdvmiagkvavvagfgdvgkgcaqalasmgarv 242
                 79************************************************************************************************* PP

                 ................................................................................................... CS
                 ................................................................................................... RF
   AdoHcyase 221 ................................................................................................... 220
                                                                                                                    
  EEA20579.1 243 ivteidpinalqaavsgfqvttmeeaapvgqifvtttgcrdilvgrhfevmkndaivcnighfdieidvawlkanaksvqnikpqvdrflmangrhiil 341
                 *************************************************************************************************** PP

                 ..............S-HHHHHHHHHHHHHHHHHHHHT......TSSS-SS.............EEE--CHHHHHHHHHCCCCCT-------HHHHHCCT CS
                 ..............xxxxxxxxxxxxxxxxxxxxxxx......xxxxxxx.............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   AdoHcyase 221 ..............hpsfvmsasftnqvlaqielfkk......ekkyekk.............vyvlpkklDekvarlhleklgaklteltkeqaeyig 286
                               h+sfvms+sf+nqvlaqi l+k       +     k             vyvlpk lDe+va+lhle+++akl++lt  qaey+g
  EEA20579.1 342 laegrlvnlgcatgHSSFVMSCSFSNQVLAQIALYKAgdaafgA-----KyiefgnegkrpvgVYVLPKILDEQVAKLHLEHVNAKLSTLTPVQAEYLG 435
                 ************************************65455541.....24445566677777************************************ PP

                 SXTTSXXSXTTXX CS
                 xxxxxxxxxxxxx RF
   AdoHcyase 287 veveGPfkpdhYr 299
                 ++v+GPfk+d Yr
  EEA20579.1 436 LDVAGPFKSDIYR 448
                 ************8 PP

>> AdoHcyase_NAD  S-adenosyl-L-homocysteine hydrolase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  274.8   3.2     1e-85   2.3e-82       1     162 []     194     355 ..     194     355 .. 1.00

  Alignments for each domain:
  == domain 1  score: 274.8 bits;  conditional E-value: 1e-85
                    HHHHHCCCCCHHHHHHH-S--TTSEEEEE--SHHHHHHHHHHHHCT-EEEEE-S-HHHHHHHHCTT-EE--HHHCTTT-SEEEE-SSSSSSB-HHH CS
  AdoHcyase_NAD   1 nlygcreslvdgikratdvllaGkvavvaGyGdvGkGcaaslkglGarvivtevdPicalqaameGfevvtleevvkkadivvtttGnkdiitleh 96 
                    nlygcresl+dgikratdv++aGkvavvaG+GdvGkGca++l ++Garvivte+dPi+alqaa+ Gf+v+t+ee++  ++i+vtttG++di+   h
     EEA20579.1 194 NLYGCRESLIDGIKRATDVMIAGKVAVVAGFGDVGKGCAQALASMGARVIVTEIDPINALQAAVSGFQVTTMEEAAPVGQIFVTTTGCRDILVGRH 289
                    89********************************************************************************************** PP

                    HCCS-TTEEEEE-SSTTTTBTHHHHHTTT-EEEEEETTEEEEE-TTS-EEEEEGGGSBCHHHTS-- CS
  AdoHcyase_NAD  97 lkkmkddaivcniGhfdseidvaaleanalkkeevkpqvdrvtlkdgkkiillaeGrllnlgcatg 162
                    ++ mk+daivcniGhfd eidva+l+ana++++++kpqvdr+ +++g++iillaeGrl+nlgcatg
     EEA20579.1 290 FEVMKNDAIVCNIGHFDIEIDVAWLKANAKSVQNIKPQVDRFLMANGRHIILLAEGRLVNLGCATG 355
                    ****************************************************************97 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.2   0.1   4.6e-10     1e-06      33     127 ..     213     303 ..     192     316 .. 0.90

  Alignments for each domain:
  == domain 1  score: 28.2 bits;  conditional E-value: 4.6e-10
                   -GTTSEEEEES-SHHHHHHHHHHHHTT-EEEEESSSHHHHHCHHHHTCEECSHHHHHHH-SEEEE-S--STTTTTSBSHHHHHCSTTTEEEEESS CS
  2-Hacid_dh_C  33 elsgktvGiiGlGrIGqavakrlkafgmkviaydrskkkeeeeeelgvelvsleellaesDivslhlpltpetrhlinaeelakmkkgailiNta 127
                    ++gk   + G+G++G+  a+ l+++g++vi+++  + +  +++  g++++++ee+    +i + +       r+++  ++++ mk++ai+ N++
    EEA20579.1 213 MIAGKVAVVAGFGDVGKGCAQALASMGARVIVTEIDPINALQAAVSGFQVTTMEEAAPVGQIFVTT----TGCRDILVGRHFEVMKNDAIVCNIG 303
                   5899********************************998889999*********999999988865....56899******************98 PP

>> IlvN  Acetohydroxy acid isomeroreductase, NADPH-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.2     2e-06    0.0045       2      64 ..     214     275 ..     213     285 .. 0.86

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 2e-06
                 HHTS-EEEES-SHHHHHHHHHHHHTT--EEEEE-TT-HHHHHHHHTT-EEEEHHHHHHT-SEE CS
        IlvN   2 lkgkkiaviGyGsqGhaqalnlrdsgldvvvglregsksvkkAkeegfevltvaeavkkadvv 64 
                 + gk  +v G+G  G+  a+ l   g  v+v+  +   ++ +A  +gf+v+t++ea+   ++ 
  EEA20579.1 214 IAGKVAVVAGFGDVGKGCAQALASMGARVIVTEIDPI-NALQAAVSGFQVTTMEEAAPVGQIF 275
                 567777788**********************998887.66677889**********9887765 PP

>> ELFV_dehydrog  Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.8   0.1   7.6e-06     0.017      22      88 ..     206     274 ..     195     346 .. 0.67

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 7.6e-06
                    HHHTTTS-STTEEEEEE--SHHHHHHHHHHHHCT-EE.EEEEESSEEEE.ETTEE-HHHHHHHHHCSSS CS
  ELFV_dehydrog  22 lkklkldslegkrvaisGsGnvgsyaallltelgakv.vavsDssGviy.dpeGldieellelkeerks 88 
                    +k++    ++gk  ++ G+G+vg+ +a+ l+++ga+v v+ +D   ++    +G+++ ++ e +   + 
     EEA20579.1 206 IKRATDVMIAGKVAVVAGFGDVGKGCAQALASMGARViVTEIDPINALQaAVSGFQVTTMEEAAPVGQI 274
                    4443333699*************************9824556665555425567766666666666666 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.1   1.5e-05     0.033       2      44 ..     220     262 ..     219     269 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 1.5e-05
                 EEES-SHHHHHHHHHHHH.TTEEEEEEESSHHHHHHHHHTTSEE CS
      TrkA_N   2 iiiGlGrvGrslaeeLse.ggkdvvvidkdeerveelreeglev 44 
                 +++G+G+vG+  a+ L + g  +v+v + d+ ++ +++  g++v
  EEA20579.1 220 VVAGFGDVGKGCAQALASmGA-RVIVTEIDPINALQAAVSGFQV 262
                 8*****************666.6********8888888777775 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.8   2.7e-05     0.061       2      40 ..     218     258 ..     217     281 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 2.7e-05
                 EEEE.--SCCHHHHHHHHHHTT-EEEEE-S-H.HHHHHHHH CS
     3HCDH_N   2 vavi.GaGtmGagiaavfasagleVvlvdise.ealekale 40 
                 vav+ G G +G+g a+++as g +V +++i++ +al++a +
  EEA20579.1 218 VAVVaGFGDVGKGCAQALASMGARVIVTEIDPiNALQAAVS 258
                 6665499***********************87244555544 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       2.3   5.1e+03      50      50 ..     103     103 ..      65     186 .. 0.55
   2 ?   11.0   0.3    0.0002      0.44       5      40 ..     214     249 ..     212     312 .. 0.80

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 2.3
  NAD_binding_7  50 l 50 
                    +
     EEA20579.1 103 W 103
                    0 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 0.0002
  NAD_binding_7   5 lkgkkvlvvGgGevAarkvrklleagakvtvvapev 40 
                    + gk  +v+G G+v+   ++ l++ ga+v+v   + 
     EEA20579.1 214 IAGKVAVVAGFGDVGKGCAQALASMGARVIVTEIDP 249
                    678999************************966653 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (449 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       449  (0.0250432); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 2970.64
//
Query:       EEA20580.1  [L=244]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (244 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       329  (0.0183502); expected 358.6 (0.02)
Passed bias filter:                      269  (0.0150036); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.47
# Mc/sec: 1565.27
//
Query:       EEA20581.1  [L=513]
Description: pre-mRNA splicing factor (Prp31), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.7e-62  208.6   0.0    1.2e-61  208.1   0.0    1.2  1  Nop       snoRNA binding domain, fibrillarin
    2.1e-47  161.0   1.0    4.9e-47  159.8   1.0    1.7  1  Prp31_C   Prp31 C terminal domain


Domain annotation for each model (and alignments):
>> Nop  snoRNA binding domain, fibrillarin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  208.1   0.0   1.4e-65   1.2e-61       7     230 .]      60     295 ..      55     295 .. 0.90

  Alignments for each domain:
  == domain 1  score: 208.1 bits;  conditional E-value: 1.4e-65
                 HHHHHHHHHHHHHHTTTSTCHHHHS-SHHHHHHHHHHCCC....CHCCT.HHTT........HHHHHHHHHHHHCHHHH-SSS-S-HHHHHHHHHHHHH CS
         Nop   7 keintlhkrvrewYswhFpELeslvkdnleYakvvklign....eredlekkee.......deelakevimaakvtastsmgaelseedlknikelcdr 94 
                 +e+ +lhk +r+ Ys +FpELe+l++++++Yak+v++++n    + ++l+++++       +  l+   +m+++v+ +++ g+++se +lk +++ c++
  EEA20581.1  60 DELARLHKVLRDYYSVRFPELETLITNPINYAKAVAILKNgpldNIKQLSTSSDnivgaplNTVLDGPSLMVVTVEGTSTRGRPMSEAELKLVLDTCEK 158
                 78999**********************************9766533444333336788854444*********************************** PP

                 HHHHHHHHHHHHHHHHHHHHHHSHHHHHHCHHHHHHHHHHHHSSHHHHHCS-HHHHTTTT-HHHHCCCHH.T-..--SSSCHHHCSHHHHHTS-CCCHH CS
         Nop  95 vleleelrkelleYlesrmsaiAPNlsaLvGeevaarLishaGgLtnLakmPastiqilGaekalfralk.kk..ntpkyGliyhselvqkatppklkk 190
                 +l+l++ r+   e ++srm++iAPNl+aL+G+++aa+++++aGgL +Lak+Pa++++  G++k  ++ l   +    +++G++y+s+++q  +p+++k+
  EEA20581.1 159 ILKLDRERTARIESVQSRMTEIAPNLTALIGSQTAAQFLNQAGGLLELAKIPACNLAAQGSKK--QEGLGfATnvGIRQQGFLYNSPMIQ-DIPNDVKR 254
                 ***************************************************************..55666544356**************.88****** PP

                 HHHHHHHHHHHHHHHHH.HTT----SHHHHHHHHHHHHHHH CS
         Nop 191 kiaRllaaKvalaaRiD.afsekdgslGkklreeiekklkk 230
                 +++R+++aK++laaR D a s++dgs+G++l++++ ++l+k
  EEA20581.1 255 QAMRIVSAKMVLAARADvARSSPDGSMGEELKQQCFHRLDK 295
                 *****************8777788***********999986 PP

>> Prp31_C  Prp31 C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  159.8   1.0   5.4e-51   4.9e-47       1     120 []     302     453 ..     302     453 .. 0.93

  Alignments for each domain:
  == domain 1  score: 159.8 bits;  conditional E-value: 5.4e-51
     Prp31_C   1 akekkaLpaPddkpkkkRGGrraRkaKerlamtelrkaqNRmaFGkeeeevgq..gdetgkglGmlgkkasgriraaqvdkktkaklskkl........ 89 
                 +k+ +aLpaPddkp++kRGGrraRkaKe++amtelrkaqNR+aFGkee+e+g+  gd+t +glGmlg++++griraaq+d++t+a+lsk++        
  EEA20581.1 302 NKGPRALPAPDDKPARKRGGRRARKAKEAVAMTELRKAQNRVAFGKEEQEAGYgtGDGT-VGLGMLGQENDGRIRAAQIDQRTRARLSKSNkgwgaatp 399
                 6899************************************************9656666.9******************************99****** PP

     Prp31_C  90 .................kkklqrssgvg......sgtasslaftpvqglelvnP 120
                                  ++k+ r+sgvg      +gtass+aftpvqglelv+P
  EEA20581.1 400 isgiasslrgpgnatvlQAKGLRTSGVGtslnatAGTASSIAFTPVQGLELVDP 453
                 **99999999999999988888888666778888*******************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (513 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       707  (0.0394333); expected 358.6 (0.02)
Passed bias filter:                      518  (0.0288917); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.43
# Mc/sec: 3555.71
//
Query:       EEA20582.1  [L=673]
Description: cell cycle control protein (Cwf4), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.4e-25   87.3  77.5    3.7e-14   52.4   4.9   14.1 15  HAT         HAT (Half-A-TPR) repeat
    3.2e-21   74.2  22.9     0.0029   18.3   0.2   11.3 11  TPR_14      Tetratricopeptide repeat
    1.3e-18   67.2   0.0    2.5e-05   24.7   0.0    7.6  7  TPR_19      Tetratricopeptide repeat
    1.9e-15   57.6  26.4      5e-05   23.4   1.2    7.2  7  Suf         Suppressor of forked protein (Suf)
    1.6e-08   34.3   5.2       0.06   13.8   0.0    7.0  6  TPR_17      Tetratricopeptide repeat
    2.9e-08   33.3   6.2         15    6.1   0.0    8.2  7  TPR_8       Tetratricopeptide repeat
    0.00073   20.0  18.4         21    6.0   0.0    8.5  9  TPR_6       Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.011   15.8  16.8        1.1    9.5   0.0    7.9  9  TPR_2       Tetratricopeptide repeat
      0.022   15.4   8.3         13    6.5   0.1    6.8  9  TPR_16      Tetratricopeptide repeat
      0.068   13.5  17.5        6.6    7.1   0.0    7.5  8  TPR_12      Tetratricopeptide repeat
       0.38   10.8  27.4      0.055   13.5   2.1    6.8  7  U3_assoc_6  U3 small nucleolar RNA-associated protein 6
       0.41   10.9   3.0         12    6.3   0.0    4.3  5  ANAPC3      Anaphase-promoting complex, cyclosome, subunit 3
        0.5   10.4   2.2         34    4.6   0.4    3.3  3  PTS_IIA     PTS system, Lactose/Cellobiose specific IIA subun
       0.66    9.0  29.9        1.9    7.5   4.4    6.1  5  NRDE-2      NRDE-2, necessary for RNA interference
        8.9    6.5   8.2         20    5.4   0.1    4.9  6  Fis1_TPR_C  Fis1 C-terminal tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> HAT  HAT (Half-A-TPR) repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   1.0   0.00091       1.1      18      30 ..      70      82 ..      54      84 .. 0.78
   2 !   15.9   0.2   7.6e-06     0.009       1      26 [.      86     112 ..      86     116 .. 0.94
   3 ?    2.1   0.1      0.16   1.9e+02       3      31 ..     122     151 ..     120     152 .. 0.86
   4 ?   -0.5   0.0       1.1   1.3e+03       7      30 ..     160     183 ..     156     185 .. 0.79
   5 !   52.4   4.9   3.1e-17   3.7e-14       2      32 .]     188     218 ..     187     218 .. 0.97
   6 ?   -0.7   0.1       1.2   1.4e+03      24      30 ..     247     253 ..     244     255 .. 0.83
   7 ?    6.0   0.7      0.01        12       1      11 [.     257     267 ..     257     269 .. 0.93
   8 ?    0.9   0.1      0.39   4.6e+02      23      31 ..     324     332 ..     320     333 .. 0.88
   9 ?    3.8   0.6     0.047        56       3      12 ..     337     346 ..     336     350 .. 0.87
  10 ?   -2.5   1.2       4.4   5.3e+03      23      31 ..     367     375 ..     365     376 .. 0.93
  11 !    6.5   0.0     0.007       8.3       1      12 [.     379     390 ..     379     413 .. 0.87
  12 !    8.8   0.6    0.0013       1.5       2      30 ..     451     480 ..     450     481 .. 0.92
  13 ?    0.7   0.0      0.44   5.2e+02       3      11 ..     486     494 ..     484     495 .. 0.87
  14 !   24.1   0.1   2.2e-08   2.6e-05       2      30 ..     521     549 ..     520     551 .. 0.97
  15 ?    2.0   0.3      0.17   2.1e+02       5      12 ..     574     581 ..     570     585 .. 0.90

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00091
                --HHHHHHHHHHH CS
         HAT 18 peVkNWikyArFE 30
                ++ +NW++yA++E
  EEA20582.1 70 INMNNWMRYAQWE 82
                99********998 PP

  == domain 2  score: 15.9 bits;  conditional E-value: 7.6e-06
                 --HHHHHHHHHHHHHHS.--HHHHHHH CS
         HAT   1 kEidRAReiYeRFvvVH.peVkNWiky 26 
                 kE  RAR+i+eR + V    V  Wi+y
  EEA20582.1  86 KEFRRARSIFERALDVDsTSVVLWIRY 112
                 8999*************9********9 PP

  == domain 3  score: 2.1 bits;  conditional E-value: 0.16
                 HHHHHHHHHHHHHHS--H.HHHHHHHHHHH CS
         HAT   3 idRAReiYeRFvvVHpeV.kNWikyArFEE 31 
                 i+ AR+  +R v + p V k W ky   EE
  EEA20582.1 122 INHARNLLDRAVTILPRVdKLWYKYVYMEE 151
                 889**************9456****99888 PP

  == domain 4  score: -0.5 bits;  conditional E-value: 1.1
                 HHHHHHHHHHS--HHHHHHHHHHH CS
         HAT   7 ReiYeRFvvVHpeVkNWikyArFE 30 
                 R+++eR++   p+   W  y + E
  EEA20582.1 160 RQVFERWMSWEPDEGAWSAYIKLE 183
                 99****998888888887777766 PP

  == domain 5  score: 52.4 bits;  conditional E-value: 3.1e-17
                 -HHHHHHHHHHHHHHS--HHHHHHHHHHHHH CS
         HAT   2 EidRAReiYeRFvvVHpeVkNWikyArFEEe 32 
                 E dRAR i++RF  VHpe +NWik+ArFEEe
  EEA20582.1 188 EFDRARAIFQRFTIVHPEPRNWIKWARFEEE 218
                 99****************************7 PP

  == domain 6  score: -0.7 bits;  conditional E-value: 1.2
                 HHHHHHH CS
         HAT  24 ikyArFE 30 
                 + yA+FE
  EEA20582.1 247 VSYAKFE 253
                 56****9 PP

  == domain 7  score: 6.0 bits;  conditional E-value: 0.01
                 --HHHHHHHHH CS
         HAT   1 kEidRAReiYe 11 
                 kE +RAR iY+
  EEA20582.1 257 KEYERARAIYK 267
                 8*********5 PP

  == domain 8  score: 0.9 bits;  conditional E-value: 0.39
                 HHHHHHHHH CS
         HAT  23 WikyArFEE 31 
                 W  +Ar EE
  EEA20582.1 324 WFDFARLEE 332
                 99******9 PP

  == domain 9  score: 3.8 bits;  conditional E-value: 0.047
                 HHHHHHHHHH CS
         HAT   3 idRAReiYeR 12 
                  dR R++YeR
  EEA20582.1 337 ADRIRDVYER 346
                 59******** PP

  == domain 10  score: -2.5 bits;  conditional E-value: 4.4
                 HHHHHHHHH CS
         HAT  23 WikyArFEE 31 
                 Wi yA +EE
  EEA20582.1 367 WIFYALWEE 375
                 ********9 PP

  == domain 11  score: 6.5 bits;  conditional E-value: 0.007
                 --HHHHHHHHHH CS
         HAT   1 kEidRAReiYeR 12 
                 k i RAR+iY+ 
  EEA20582.1 379 KDIGRARQIYQE 390
                 7899******95 PP

  == domain 12  score: 8.8 bits;  conditional E-value: 0.0013
                 -HHHHHHHHHHHHHHS.--HHHHHHHHHHH CS
         HAT   2 EidRAReiYeRFvvVH.peVkNWikyArFE 30 
                 E +R R  Ye+ +     + + Wik+A  E
  EEA20582.1 451 EFNRCRTLYEKQIEWNaANSQAWIKFAELE 480
                 789**********9999**********877 PP

  == domain 13  score: 0.7 bits;  conditional E-value: 0.44
                 HHHHHHHHH CS
         HAT   3 idRAReiYe 11 
                  +RAR i+e
  EEA20582.1 486 LERARAIFE 494
                 69*****98 PP

  == domain 14  score: 24.1 bits;  conditional E-value: 2.2e-08
                 -HHHHHHHHHHHHHHS--HHHHHHHHHHH CS
         HAT   2 EidRAReiYeRFvvVHpeVkNWikyArFE 30 
                 E dR R+ YeR +     Vk Wi yA+FE
  EEA20582.1 521 EYDRTRDLYERLLQKTDHVKVWINYAKFE 549
                 89**************************9 PP

  == domain 15  score: 2.0 bits;  conditional E-value: 0.17
                 HHHHHHHH CS
         HAT   5 RAReiYeR 12 
                 RAR i+eR
  EEA20582.1 574 RARKIFER 581
                 9******9 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.0       3.9   4.7e+03      20      31 ..      22      33 ..      20      42 .. 0.83
   2 !   18.3   0.2   2.4e-06    0.0029       4      43 ..      75     114 ..      72     115 .. 0.94
   3 !    9.4   0.0    0.0017         2       3      42 ..     108     147 ..     106     149 .. 0.93
   4 ?    1.9   0.0      0.45   5.3e+02       2      27 ..     141     166 ..     140     168 .. 0.92
   5 !   10.1   0.0     0.001       1.2       3      43 ..     175     214 ..     173     215 .. 0.89
   6 !    7.1   0.0    0.0099        12       7      42 ..     249     284 ..     244     286 .. 0.87
   7 !   14.2   0.1     5e-05      0.06       3      42 ..     323     364 ..     321     366 .. 0.81
   8 ?    5.4   0.0     0.033        40      11      43 ..     375     411 ..     365     412 .. 0.81
   9 !    7.7   0.0    0.0061       7.2       2      38 ..     404     440 ..     403     443 .. 0.91
  10 ?    3.6   0.3      0.12   1.5e+02       2      30 ..     471     499 ..     470     507 .. 0.87
  11 !   12.4   0.0   0.00019      0.23       3      43 ..     508     547 ..     505     548 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 3.9
      TPR_14 20 Aiallrralala 31
                A++llr+a++++
  EEA20582.1 22 AEQLLREAVDRQ 33
                99******9875 PP

  == domain 2  score: 18.3 bits;  conditional E-value: 2.4e-06
      TPR_14   4 llalaeallalGdpdeAiallrralalaPddaeawlllaq 43 
                 ++++a+ +l++ ++++A+ +++ral+ + ++ ++w+++ +
  EEA20582.1  75 WMRYAQWELEQKEFRRARSIFERALDVDSTSVVLWIRYIE 114
                 99***********************************986 PP

  == domain 3  score: 9.4 bits;  conditional E-value: 0.0017
      TPR_14   3 allalaeallalGdpdeAiallrralalaPddaeawllla 42 
                 ++ ++ ea++  ++   A++ll+ra+   P  + +w+ ++
  EEA20582.1 108 LWIRYIEAEMKTRNINHARNLLDRAVTILPRVDKLWYKYV 147
                 7999********************************9886 PP

  == domain 4  score: 1.9 bits;  conditional E-value: 0.45
      TPR_14   2 eallalaeallalGdpdeAiallrra 27 
                 +++++++  +++lG+  + +++++r+
  EEA20582.1 141 KLWYKYVYMEETLGNIPGTRQVFERW 166
                 58********************9997 PP

  == domain 5  score: 10.1 bits;  conditional E-value: 0.001
      TPR_14   3 allalaeallalGdpdeAiallrralalaPddaeawlllaq 43 
                 a+ a+ +++ +  ++d+A+a+++r    +P+ ++ w+ +a+
  EEA20582.1 175 AWSAYIKLEKRYNEFDRARAIFQRFTIVHPE-PRNWIKWAR 214
                 8***********************9999998.788877776 PP

  == domain 6  score: 7.1 bits;  conditional E-value: 0.0099
      TPR_14   7 laeallalGdpdeAiallrralalaPddaeawllla 42 
                 +a++++ l ++++A+a+++ al++ P +  + l+ a
  EEA20582.1 249 YAKFEAKLKEYERARAIYKFALDRLPRSKSVTLHQA 284
                 899***********************9887776655 PP

  == domain 7  score: 14.2 bits;  conditional E-value: 5e-05
      TPR_14   3 allalaeallalGdpdeAiallrralalaP..ddaeawllla 42 
                 ++ + a++++++Gd d+ +++++ra+a+ P  ++ + w+++ 
  EEA20582.1 323 VWFDFARLEETSGDADRIRDVYERAIAQIPpsQEKRHWRRYI 364
                 68899**********************976433346777776 PP

  == domain 8  score: 5.4 bits;  conditional E-value: 0.033
      TPR_14  11 llalGdpdeAiallrralalaP....ddaeawlllaq 43 
                 ++++ d  +A+++++++l+l P    ++a +wl+ aq
  EEA20582.1 375 EMESKDIGRARQIYQECLKLIPhkkfTFAKIWLMKAQ 411
                 4678999************988777788999999998 PP

  == domain 9  score: 7.7 bits;  conditional E-value: 0.0061
      TPR_14   2 eallalaeallalGdpdeAiallrralalaPddaeaw 38 
                 + +l+ a+++ ++ ++++A++ l +a+  +P+d  ++
  EEA20582.1 404 KIWLMKAQFEIRQMELQAARKTLGQAIGMCPKDKLFR 440
                 579****************************998766 PP

  == domain 10  score: 3.6 bits;  conditional E-value: 0.12
      TPR_14   2 eallalaeallalGdpdeAiallrralal 30 
                 +a+ + ae+++ l+d+++A+a+++  +++
  EEA20582.1 471 QAWIKFAELERGLEDLERARAIFELGIEQ 499
                 5899999999*************998885 PP

  == domain 11  score: 12.4 bits;  conditional E-value: 0.00019
      TPR_14   3 allalaeallalGdpdeAiallrralalaPddaeawlllaq 43 
                 +++a+ ++++  G++d+ ++l++r+l++  d+  +w+ +a+
  EEA20582.1 508 VWKAYIDFEEYEGEYDRTRDLYERLLQKT-DHVKVWINYAK 547
                 599***********************954.67999999997 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.0   2.1e-08   2.5e-05       2      52 ..      83     133 ..      82     143 .. 0.94
   2 ?    3.1   0.0      0.11   1.4e+02      12      50 ..     161     198 ..     153     207 .. 0.78
   3 ?    2.2   0.0      0.23   2.7e+02      32      54 ..     250     272 ..     239     284 .. 0.60
   4 ?    3.9   0.0     0.064        76      15      43 ..     311     339 ..     308     356 .. 0.78
   5 !   14.3   0.0   3.6e-05     0.043       2      51 ..     376     429 ..     375     440 .. 0.93
   6 ?    5.4   0.1     0.022        26      13      52 ..     458     497 ..     456     507 .. 0.87
   7 ?    1.6   0.0      0.33     4e+02       4      34 ..     519     548 ..     518     552 .. 0.81

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 2.1e-08
      TPR_19   2 laegdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalp 52 
                 l+++ + +A +++e+al+ d  +  ++++++ea +++ +++ A++lLd++ 
  EEA20582.1  83 LEQKEFRRARSIFERALDVDSTSVVLWIRYIEAEMKTRNINHARNLLDRAV 133
                 89**********************************************985 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.11
      TPR_19  12 alleqalqedpknaearllLAeallalgqldeAealLda 50 
                 + +e+ ++ +p+   a+ +++++    +++d A+a+ ++
  EEA20582.1 161 QVFERWMSWEPDE-GAWSAYIKLEKRYNEFDRARAIFQR 198
                 5677777778854.5555599**************9987 PP

  == domain 3  score: 2.2 bits;  conditional E-value: 0.23
      TPR_19  32 AeallalgqldeAealLdalpee 54 
                 A+   +l++++ A+a+ + +++ 
  EEA20582.1 250 AKFEAKLKEYERARAIYKFALDR 272
                 55555666666666655433333 PP

  == domain 4  score: 3.9 bits;  conditional E-value: 0.064
      TPR_19  15 eqalqedpknaearllLAeallalgqlde 43 
                 e+ ++e+p n +++ + A++   +g+ d 
  EEA20582.1 311 EEQIKENPRNYDVWFDFARLEETSGDADR 339
                 555799**************999999886 PP

  == domain 5  score: 14.3 bits;  conditional E-value: 3.6e-05
      TPR_19   2 laegdyaeAlalleqalqedpk....naearllLAeallalgqldeAealLdal 51 
                 ++++d  +A +++++ l+  p+     a ++l  A+  + + +l++A+++L ++
  EEA20582.1 376 MESKDIGRARQIYQECLKLIPHkkftFAKIWLMKAQFEIRQMELQAARKTLGQA 429
                 6899***********************************************876 PP

  == domain 6  score: 5.4 bits;  conditional E-value: 0.022
      TPR_19  13 lleqalqedpknaearllLAeallalgqldeAealLdalp 52 
                 l+e+ ++ ++ n+ a++  Ae+   l +l+ A+a+ +   
  EEA20582.1 458 LYEKQIEWNAANSQAWIKFAELERGLEDLERARAIFELGI 497
                 67888899**************************987655 PP

  == domain 7  score: 1.6 bits;  conditional E-value: 0.33
      TPR_19   4 egdyaeAlalleqalqedpknaearllLAea 34 
                 eg y++  +l+e++lq+  ++  +++++A+ 
  EEA20582.1 519 EGEYDRTRDLYERLLQK-TDHVKVWINYAKF 548
                 89***********7666.7788888888876 PP

>> Suf  Suppressor of forked protein (Suf)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.4   1.2   4.2e-08     5e-05      20     135 ..      57     188 ..      51     199 .. 0.94
   2 ?    4.6   0.1     0.023        28      84     127 ..     187     226 ..     186     230 .. 0.78
   3 !   17.2   0.9   3.4e-06     0.004      68     133 ..     242     307 ..     233     319 .. 0.84
   4 ?    2.4   0.1      0.11   1.3e+02     106     139 ..     320     353 ..     303     369 .. 0.62
   5 ?    2.0   0.0      0.14   1.6e+02      85     124 ..     336     420 ..     333     437 .. 0.60
   6 !   15.2   0.6   1.3e-05     0.016      83     134 ..     483     533 ..     381     540 .. 0.95
   7 !    8.7   0.5    0.0013       1.6      86     148 ..     572     635 ..     567     662 .. 0.82

  Alignments for each domain:
  == domain 1  score: 23.4 bits;  conditional E-value: 4.2e-08
         Suf  20 aRkvFkkARkkprltyevyvasAllEyyiskdkkvAtkIFelGlKkFpedeefvlkYldyLislnddnnaRvlfekvvsklskeke............. 105
                  Rk F++   ++r++ + ++  A+ E   +k+ + A+ IFe++l   +++    ++Y++  ++  + n aR l++++v+ l   ++             
  EEA20582.1  57 KRKEFEDYVRRNRINMNNWMRYAQWELE-QKEFRRARSIFERALDVDSTSVVLWIRYIEAEMKTRNINHARNLLDRAVTILPRVDKlwykyvymeetlg 154
                 5788888888889999999999999999.999999**********************************************99999************* PP

         Suf 106 ....akelykkfleyestfgdlssilklekRmee 135
                     +++++++++++e   g  s+ +klekR++e
  EEA20582.1 155 nipgTRQVFERWMSWEPDEGAWSAYIKLEKRYNE 188
                 ********************************98 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.023
         Suf  84 nddnnaRvlfekvvsklskekeakelykkfleyestfgdlssil 127
                 n+ ++aR++f++    + +e+     + k++++e ++g  + + 
  EEA20582.1 187 NEFDRARAIFQRFT-IVHPEP---RNWIKWARFEEEYGTSDLVR 226
                 8999*******963.344444...45************888775 PP

  == domain 3  score: 17.2 bits;  conditional E-value: 3.4e-06
         Suf  68 edeefvlkYldyLislnddnnaRvlfekvvsklskekeakelykkfleyestfgdlssilk..lekRm 133
                 + e+  + Y ++  +l + ++aR+++  ++ +l   k +  l + +  +e++fgd + +    l+kR+
  EEA20582.1 242 D-EKIFVSYAKFEAKLKEYERARAIYKFALDRLPRSK-SVTLHQAYTTFEKQFGDREGVEDviLNKRR 307
                 4.455568*****************************.*****************9888652245555 PP

  == domain 4  score: 2.4 bits;  conditional E-value: 0.11
         Suf 106 akelykkfleyestfgdlssilklekRmeelfpe 139
                   +++  f++ e t gd + i  + +R  +  p 
  EEA20582.1 320 NYDVWFDFARLEETSGDADRIRDVYERAIAQIPP 353
                 4478888888888888888888877776554443 PP

  == domain 5  score: 2.0 bits;  conditional E-value: 0.14
         Suf  85 ddnnaRvlfekvvsklskeke.............................................akelykkfleyestfgdls 124
                 d +++R ++e++++++ + +e                                               +++   +++e ++ +l+
  EEA20582.1 336 DADRIRDVYERAIAQIPPSQEkrhwrryiylwifyalweemeskdigrarqiyqeclkliphkkftFAKIWLMKAQFEIRQMELQ 420
                 6677888888888887777754555555555555555555555555554444444444444444455666666666666666665 PP

  == domain 6  score: 15.2 bits;  conditional E-value: 1.3e-05
         Suf  83 lnddnnaRvlfekvvsklskekeakelykkfleyestfgdlssilklekRme 134
                 l+d ++aR++fe  +++++ +   + ++k ++++e   g+ + +  l +R+ 
  EEA20582.1 483 LEDLERARAIFELGIEQPTLDM-PELVWKAYIDFEEYEGEYDRTRDLYERLL 533
                 68999****************9.9*******************999999876 PP

  == domain 7  score: 8.7 bits;  conditional E-value: 0.0013
         Suf  86 dnnaRvlfekvvsklskeke....akelykkfleyestfgdlssilklekRmeelfpedskleqfvd 148
                 +++aR +fe++ + + k+k+      +l + +  +e+ +g+ +    +ek+m   +++  kl++  d
  EEA20582.1 572 KRRARKIFERANKVM-KDKDlkeeRVDLLNAWKAFEQAHGSAEDLAAIEKQMPRRVKKRRKLDD--D 635
                 5789*****986554.55543555778*************************999999777664..4 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0       0.2   2.4e+02       2      19 ..      95     112 ..      94     127 .. 0.87
   2 ?    0.8   0.0       0.7   8.3e+02      18      34 .]     248     264 ..     244     264 .. 0.87
   3 !   13.8   0.0     5e-05      0.06       6      33 ..     314     341 ..     310     342 .. 0.89
   4 ?    1.5   0.0      0.41   4.8e+02       2      33 ..     388     423 ..     387     424 .. 0.76
   5 !    8.5   0.1    0.0025       2.9       1      33 [.     458     490 ..     458     491 .. 0.95
   6 ?    1.6   0.0      0.39   4.6e+02       9      23 ..     535     549 ..     528     553 .. 0.72

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.2
      TPR_17   2 ylkaleldPnnadaynnL 19 
                 +++al+ d ++++++  +
  EEA20582.1  95 FERALDVDSTSVVLWIRY 112
                 9*************9876 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.7
      TPR_17  18 nLAelllknGdlmtArq 34 
                  +A++ +k++++++Ar+
  EEA20582.1 248 SYAKFEAKLKEYERARA 264
                 69*************95 PP

  == domain 3  score: 13.8 bits;  conditional E-value: 5e-05
      TPR_17   6 leldPnnadaynnLAelllknGdlmtAr 33 
                 ++ +P n d+++  A+l +  Gd ++ r
  EEA20582.1 314 IKENPRNYDVWFDFARLEETSGDADRIR 341
                 899********************99976 PP

  == domain 4  score: 1.5 bits;  conditional E-value: 0.41
      TPR_17   2 ylkalel..dPnn..adaynnLAelllknGdlmtAr 33 
                 y+++l+l  +++   a+ + ++A++  ++ +l+ Ar
  EEA20582.1 388 YQECLKLipHKKFtfAKIWLMKAQFEIRQMELQAAR 423
                 777777744444477999******999999998887 PP

  == domain 5  score: 8.5 bits;  conditional E-value: 0.0025
      TPR_17   1 lylkaleldPnnadaynnLAelllknGdlmtAr 33 
                 ly+k +e +  n+ a+   Ael + + dl++Ar
  EEA20582.1 458 LYEKQIEWNAANSQAWIKFAELERGLEDLERAR 490
                 79999***************************9 PP

  == domain 6  score: 1.6 bits;  conditional E-value: 0.39
      TPR_17   9 dPnnadaynnLAell 23 
                   ++++++ n+A++ 
  EEA20582.1 535 KTDHVKVWINYAKFE 549
                 44679*******986 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.0     0.082        98       6      32 ..      77     103 ..      73     105 .. 0.80
   2 ?    2.2   0.3      0.23   2.7e+02      10      25 ..     252     267 ..     244     272 .. 0.79
   3 ?    2.7   0.0      0.16   1.9e+02       2      28 ..     322     348 ..     321     352 .. 0.92
   4 ?    6.0   0.0     0.013        16      13      32 ..     377     396 ..     367     398 .. 0.89
   5 ?    5.5   0.0      0.02        23       1      34 []     403     436 ..     403     436 .. 0.95
   6 ?    0.8   0.0      0.64   7.7e+02      13      34 .]     448     469 ..     444     469 .. 0.82
   7 ?    6.1   0.0     0.012        15       2      29 ..     471     498 ..     470     499 .. 0.92

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.082
                 HHHHHHHHTT-HHHHHHHHHHHHHHHH CS
       TPR_8   6 nlgsiylklgdyeeAkeyyekaleldp 32 
                 + ++  l+++++  A + +e+al+ d 
  EEA20582.1  77 RYAQWELEQKEFRRARSIFERALDVDS 103
                 5555567889999**********9986 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.23
                 HHHHTT-HHHHHHHHH CS
       TPR_8  10 iylklgdyeeAkeyye 25 
                    kl++ye A + y+
  EEA20582.1 252 FEAKLKEYERARAIYK 267
                 5579**********98 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.16
                 CHHHHHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_8   2 eayynlgsiylklgdyeeAkeyyekal 28 
                 ++++  +++ ++ gd +    +ye+a+
  EEA20582.1 322 DVWFDFARLEETSGDADRIRDVYERAI 348
                 79***********************98 PP

  == domain 4  score: 6.0 bits;  conditional E-value: 0.013
                 HTT-HHHHHHHHHHHHHHHH CS
       TPR_8  13 klgdyeeAkeyyekaleldp 32 
                 + +d+  A + y+++l+l p
  EEA20582.1 377 ESKDIGRARQIYQECLKLIP 396
                 679999************88 PP

  == domain 5  score: 5.5 bits;  conditional E-value: 0.02
                 CCHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH. CS
       TPR_8   1 aeayynlgsiylklgdyeeAkeyyekaleldpdn 34 
                 a++++++++  + + ++++A +++ +a+ + p++
  EEA20582.1 403 AKIWLMKAQFEIRQMELQAARKTLGQAIGMCPKD 436
                 789***************************9986 PP

  == domain 6  score: 0.8 bits;  conditional E-value: 0.64
                 HTT-HHHHHHHHHHHHHHHHH. CS
       TPR_8  13 klgdyeeAkeyyekaleldpdn 34 
                 +l +++     yek +e++ +n
  EEA20582.1 448 QLFEFNRCRTLYEKQIEWNAAN 469
                 67778889999*******9875 PP

  == domain 7  score: 6.1 bits;  conditional E-value: 0.012
                 CHHHHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8   2 eayynlgsiylklgdyeeAkeyyekale 29 
                 +a+ + + + + l+d+e A + +e  +e
  EEA20582.1 471 QAWIKFAELERGLEDLERARAIFELGIE 498
                 79*********************98776 PP

>> TPR_6  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.0     0.017        21       4      28 ..      76     100 ..      74     105 .. 0.88
   2 ?    5.2   0.0     0.033        39      13      27 ..     182     200 ..     175     205 .. 0.74
   3 ?    3.9   0.3     0.083        99      11      33 .]     254     276 ..     248     276 .. 0.82
   4 ?    1.3   0.0      0.56   6.7e+02       9      28 ..     330     349 ..     322     352 .. 0.78
   5 ?    1.6   0.0      0.46   5.5e+02      14      28 ..     379     393 ..     367     396 .. 0.77
   6 ?   -0.9   0.0       2.9   3.4e+03       7      27 ..     408     430 ..     405     434 .. 0.68
   7 ?   -0.1   0.1       1.6   1.9e+03       7      24 ..     477     494 ..     471     495 .. 0.74
   8 ?    5.6   0.1     0.025        29      13      29 ..     519     535 ..     507     535 .. 0.82
   9 ?   -1.8   0.1       5.5   6.6e+03      16      25 ..     572     581 ..     569     583 .. 0.83

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.017
                 HHHHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   4 yklalsyrklgdtdkAlealerlik 28 
                 ++ a+  +++++ ++A+ ++er ++
  EEA20582.1  76 MRYAQWELEQKEFRRARSIFERALD 100
                 5789999999************986 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.033
                 H....HHHHHHHHHHHHHH CS
       TPR_6  13 l....gdtdkAlealerli 27 
                 l    ++ d+A+++++r+ 
  EEA20582.1 182 LekryNEFDRARAIFQRFT 200
                 34455899*********96 PP

  == domain 3  score: 3.9 bits;  conditional E-value: 0.083
                 HHHHHHHHHHHHHHHHHHH-TT- CS
       TPR_6  11 rklgdtdkAlealerlikeYPdS 33 
                  kl+++++A+++++  +++ P S
  EEA20582.1 254 AKLKEYERARAIYKFALDRLPRS 276
                 4579**********999998877 PP

  == domain 4  score: 1.3 bits;  conditional E-value: 0.56
                 HHHHHHHHHHHHHHHHHHHH CS
       TPR_6   9 syrklgdtdkAlealerlik 28 
                 + +  gd+d+ ++ +er i 
  EEA20582.1 330 LEETSGDADRIRDVYERAIA 349
                 444448***********996 PP

  == domain 5  score: 1.6 bits;  conditional E-value: 0.46
                 HHHHHHHHHHHHHHH CS
       TPR_6  14 gdtdkAlealerlik 28 
                 +d  +A++++++++k
  EEA20582.1 379 KDIGRARQIYQECLK 393
                 67789*******987 PP

  == domain 6  score: -0.9 bits;  conditional E-value: 2.9
                 HHHHHH.HH.HHHHHHHHHHHHH CS
       TPR_6   7 alsyrk.lg.dtdkAlealerli 27 
                  +++++  + + ++A+++l + i
  EEA20582.1 408 MKAQFEiRQmELQAARKTLGQAI 430
                 55566644336679999998876 PP

  == domain 7  score: -0.1 bits;  conditional E-value: 1.6
                 HHHHHHHHHHHHHHHHHH CS
       TPR_6   7 alsyrklgdtdkAleale 24 
                 a++ r l d ++A++++e
  EEA20582.1 477 AELERGLEDLERARAIFE 494
                 5555666799*****997 PP

  == domain 8  score: 5.6 bits;  conditional E-value: 0.025
                 HHHHHHHHHHHHHHHHH CS
       TPR_6  13 lgdtdkAlealerlike 29 
                  g++d+ ++++erl+++
  EEA20582.1 519 EGEYDRTRDLYERLLQK 535
                 47************986 PP

  == domain 9  score: -1.8 bits;  conditional E-value: 5.5
                 HHHHHHHHHH CS
       TPR_6  16 tdkAlealer 25 
                 +++A++++er
  EEA20582.1 572 KRRARKIFER 581
                 5799***998 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.0   0.00093       1.1       4      32 ..      75     103 ..      73     105 .. 0.91
   2 ?    2.0   0.0      0.24   2.8e+02      11      32 ..     116     137 ..     114     139 .. 0.88
   3 ?   -2.4   0.0       6.2   7.5e+03      15      26 ..     187     198 ..     185     201 .. 0.83
   4 ?    2.0   0.2      0.24   2.9e+02      12      29 ..     254     271 ..     247     276 .. 0.78
   5 ?   -2.9   0.0       8.8     1e+04      22      30 ..     342     350 ..     341     352 .. 0.73
   6 ?    5.2   0.0     0.022        27      12      33 ..     376     397 ..     374     398 .. 0.89
   7 ?   -1.2   0.0       2.5     3e+03       2      33 ..     404     435 ..     403     436 .. 0.78
   8 ?    0.4   0.1       0.8   9.6e+02       3      27 ..     472     496 ..     470     499 .. 0.76
   9 ?   -1.3   0.1       2.7   3.2e+03      13      29 ..     518     534 ..     517     537 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00093
       TPR_2   4 lynlGlayyklgdyeeAleafekAleldP 32 
                 +++ ++  ++++++ +A+  fe+Al  d 
  EEA20582.1  75 WMRYAQWELEQKEFRRARSIFERALDVDS 103
                 89999********************9875 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.24
       TPR_2  11 yyklgdyeeAleafekAleldP 32 
                  +k  + + A++++++A+ + P
  EEA20582.1 116 EMKTRNINHARNLLDRAVTILP 137
                 689999************9988 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 6.2
       TPR_2  15 gdyeeAleafek 26 
                 +++++A++ f++
  EEA20582.1 187 NEFDRARAIFQR 198
                 679999999987 PP

  == domain 4  score: 2.0 bits;  conditional E-value: 0.24
       TPR_2  12 yklgdyeeAleafekAle 29 
                 +kl++ye+A++ ++ Al 
  EEA20582.1 254 AKLKEYERARAIYKFALD 271
                 6899******99976665 PP

  == domain 5  score: -2.9 bits;  conditional E-value: 8.8
       TPR_2  22 eafekAlel 30 
                 + +e+A++ 
  EEA20582.1 342 DVYERAIAQ 350
                 679999976 PP

  == domain 6  score: 5.2 bits;  conditional E-value: 0.022
       TPR_2  12 yklgdyeeAleafekAleldPn 33 
                 ++++d  +A++ ++++l+l P+
  EEA20582.1 376 MESKDIGRARQIYQECLKLIPH 397
                 5678999************996 PP

  == domain 7  score: -1.2 bits;  conditional E-value: 2.5
       TPR_2   2 ealynlGlayyklgdyeeAleafekAleldPn 33 
                 +++ + ++  +++ +++ A++ + +A+  +P+
  EEA20582.1 404 KIWLMKAQFEIRQMELQAARKTLGQAIGMCPK 435
                 667777777777778999***99999988886 PP

  == domain 8  score: 0.4 bits;  conditional E-value: 0.8
       TPR_2   3 alynlGlayyklgdyeeAleafekA 27 
                 a+   +++ + l d+e+A++ fe  
  EEA20582.1 472 AWIKFAELERGLEDLERARAIFELG 496
                 6677777888899999999988865 PP

  == domain 9  score: -1.3 bits;  conditional E-value: 2.7
       TPR_2  13 klgdyeeAleafekAle 29 
                 + g+y++ ++++e+ l+
  EEA20582.1 518 YEGEYDRTRDLYERLLQ 534
                 6789999999****998 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.1       2.7   3.2e+03      16      33 ..      22      36 ..      21      44 .. 0.70
   2 ?    6.5   0.1     0.011        13       8      30 ..      83     105 ..      79     138 .. 0.81
   3 ?   -1.7   0.0         4   4.8e+03       9      52 ..     118     158 ..     113     166 .. 0.71
   4 ?    0.8   0.0      0.66   7.9e+02      12      29 ..     188     205 ..     185     209 .. 0.84
   5 ?    3.1   0.1      0.13   1.5e+02       9      33 ..     255     276 ..     252     288 .. 0.78
   6 ?    0.7   0.0       0.7   8.4e+02      24      65 ..     314     352 ..     309     355 .. 0.77
   7 ?   -0.7   0.0         2   2.4e+03      33      65 ..     402     434 ..     373     436 .. 0.65
   8 ?   -2.3   0.1         6   7.2e+03      42      57 ..     478     493 ..     468     497 .. 0.55
   9 ?   -2.7   0.0       8.2   9.8e+03      11      27 ..     520     536 ..     518     546 .. 0.76

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 2.7
      TPR_16 16 AaaaleaalkrdpssPda 33
                A+ +l++a++r+ +    
  EEA20582.1 22 AEQLLREAVDRQEE---G 36
                78888999999844...3 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.011
      TPR_16   8 lragdyddAaaaleaalkrdpss 30 
                 l+++++++A+  +e+al+ d+ s
  EEA20582.1  83 LEQKEFRRARSIFERALDVDSTS 105
                 799***************99555 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 4
      TPR_16   9 ragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlae 52 
                 + ++   A+++l++a+      P+    ++ +  +   +g+ ++
  EEA20582.1 118 KTRNINHARNLLDRAVTIL---PRVDKLWYKYVYMEETLGNIPG 158
                 5667777999999999888...8777777777777777777666 PP

  == domain 4  score: 0.8 bits;  conditional E-value: 0.66
      TPR_16  12 dyddAaaaleaalkrdps 29 
                 ++d+A+a +++++  +p+
  EEA20582.1 188 EFDRARAIFQRFTIVHPE 205
                 79**********999944 PP

  == domain 5  score: 3.1 bits;  conditional E-value: 0.13
      TPR_16   9 ragdyddAaaaleaalkrdpssPda 33 
                 ++++y++A+a ++ al+r    P+ 
  EEA20582.1 255 KLKEYERARAIYKFALDRL---PRS 276
                 678999****999999999...554 PP

  == domain 6  score: 0.7 bits;  conditional E-value: 0.7
      TPR_16  24 lkrdpssPdaaeAllllgdaalrqgrlaeAaalyraalraap 65 
                 +k +   P++++ ++  +++    g+ ++ +++y++a+++ p
  EEA20582.1 314 IKEN---PRNYDVWFDFARLEETSGDADRIRDVYERAIAQIP 352
                 5667...99999999999999999998888888888886655 PP

  == domain 7  score: -0.7 bits;  conditional E-value: 2
      TPR_16  33 aaeAllllgdaalrqgrlaeAa.alyraalraap 65 
                  a  +l +++   rq +l++A+  l +a  +  p
  EEA20582.1 402 FAKIWLMKAQFEIRQMELQAARkTLGQAI-GMCP 434
                 56778888888888888999987776664.6655 PP

  == domain 8  score: -2.3 bits;  conditional E-value: 6
      TPR_16  42 daalrqgrlaeAaaly 57 
                 ++   + +l++A+a +
  EEA20582.1 478 ELERGLEDLERARAIF 493
                 4444445555555444 PP

  == domain 9  score: -2.7 bits;  conditional E-value: 8.2
      TPR_16  11 gdyddAaaaleaalkrd 27 
                 g+yd+ + ++e++l + 
  EEA20582.1 520 GEYDRTRDLYERLLQKT 536
                 77888888999998776 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.2       3.9   4.7e+03      64      76 ..      22      34 ..      21      35 .. 0.79
   2 ?    7.1   0.0    0.0055       6.6      51      74 ..      78     101 ..      71     105 .. 0.67
   3 ?    5.5   0.0     0.018        21       7      32 ..     247     272 ..     243     289 .. 0.87
   4 ?    2.1   0.0      0.21   2.5e+02      49      73 ..     325     349 ..     314     352 .. 0.87
   5 ?    3.2   0.1     0.089   1.1e+02      12      73 ..     330     393 ..     323     396 .. 0.54
   6 ?   -2.2   0.1       4.4   5.2e+03       4      30 ..     404     430 ..     402     433 .. 0.77
   7 ?    2.2   0.1      0.18   2.2e+02      45      69 ..     470     494 ..     451     499 .. 0.64
   8 ?   -0.2   0.1       1.1   1.3e+03      12      31 ..     515     534 ..     508     537 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 3.9
      TPR_12 64 Alelleealaiae 76
                A++ll+ea+++ e
  EEA20582.1 22 AEQLLREAVDRQE 34
                8999999998876 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0055
      TPR_12  51 LgrlyralgryeeAlelleealai 74 
                 ++++ +++++++ A++++e+al++
  EEA20582.1  78 YAQWELEQKEFRRARSIFERALDV 101
                 456666667777777777777665 PP

  == domain 3  score: 5.5 bits;  conditional E-value: 0.018
      TPR_12   7 nnlaavlrrlgrydeAlellekalei 32 
                 + +a ++++l++y+ A+++++ al++
  EEA20582.1 247 VSYAKFEAKLKEYERARAIYKFALDR 272
                 56799999**************9987 PP

  == domain 4  score: 2.1 bits;  conditional E-value: 0.21
      TPR_12  49 rnLgrlyralgryeeAlelleeala 73 
                 ++ +rl + +g+ +  ++ +e+a+a
  EEA20582.1 325 FDFARLEETSGDADRIRDVYERAIA 349
                 6789999999999999999999987 PP

  == domain 5  score: 3.2 bits;  conditional E-value: 0.089
      TPR_12  12 vlrrlgrydeAlellekaleiarrllGpdh.pltattlrnLgrlyr.algryeeAlelleeala 73 
                 ++   g+ d  ++ +e+a++++  ++++ h   ++   + ++ + + ++++   A+++++e+l+
  EEA20582.1 330 LEETSGDADRIRDVYERAIAQIPPSQEKRHwRRYIYLWIFYALWEEmESKDIGRARQIYQECLK 393
                 4444555555666666666655444444444555555555555655445666666666666665 PP

  == domain 6  score: -2.2 bits;  conditional E-value: 4.4
      TPR_12   4 talnnlaavlrrlgrydeAlellekal 30 
                 +++   a+++ r+ +++ A++ l +a+
  EEA20582.1 404 KIWLMKAQFEIRQMELQAARKTLGQAI 430
                 566557888889999999999988875 PP

  == domain 7  score: 2.2 bits;  conditional E-value: 0.18
      TPR_12  45 attlrnLgrlyralgryeeAlelle 69 
                 +++ +  ++l r l+++e A++++e
  EEA20582.1 470 SQAWIKFAELERGLEDLERARAIFE 494
                 5556666666666666666666665 PP

  == domain 8  score: -0.2 bits;  conditional E-value: 1.1
      TPR_12  12 vlrrlgrydeAlellekale 31 
                 ++ + g+yd  ++l+e+ l+
  EEA20582.1 515 FEEYEGEYDRTRDLYERLLQ 534
                 56778999999999999986 PP

>> U3_assoc_6  U3 small nucleolar RNA-associated protein 6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   2.1   4.6e-05     0.055      27      63 ..      56      92 ..      55      94 .. 0.96
   2 ?    5.0   0.3     0.021        25      23      63 ..      86     126 ..      84     128 .. 0.86
   3 ?    0.4   0.1      0.57   6.8e+02      45      64 ..     245     264 ..     241     283 .. 0.84
   4 ?   -0.6   0.1       1.2   1.4e+03      44      63 ..     437     456 ..     432     461 .. 0.82
   5 ?    5.7   0.1     0.012        15      29      64 ..     456     491 ..     449     503 .. 0.92
   6 ?    3.1   0.4     0.082        99      30      56 ..     526     552 ..     497     581 .. 0.83
   7 ?   -3.0   0.1       6.6   7.9e+03      60      65 ..     626     631 ..     616     644 .. 0.48

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 4.6e-05
  U3_assoc_6 27 kkrrkfEyklqrrgkkkedflkYieyElnLeklrkkR 63
                +kr++fE  + r + + +++++Y+++El+ ++ r+ R
  EEA20582.1 56 RKRKEFEDYVRRNRINMNNWMRYAQWELEQKEFRRAR 92
                79********************************998 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.021
  U3_assoc_6  23 keIvkkrrkfEyklqrrgkkkedflkYieyElnLeklrkkR 63 
                 ke  + r+ fE +l   + +   +++Yie E++  ++ + R
  EEA20582.1  86 KEFRRARSIFERALDVDSTSVVLWIRYIEAEMKTRNINHAR 126
                 666788999***********************988776665 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.57
  U3_assoc_6  45 dflkYieyElnLeklrkkRr 64 
                  f++Y+++E +L++  + R 
  EEA20582.1 245 IFVSYAKFEAKLKEYERARA 264
                 5999********99888875 PP

  == domain 4  score: -0.6 bits;  conditional E-value: 1.2
  U3_assoc_6  44 edflkYieyElnLeklrkkR 63 
                 + f  Yi+ E +L +  + R
  EEA20582.1 437 KLFRGYIDLERQLFEFNRCR 456
                 56999********9988777 PP

  == domain 5  score: 5.7 bits;  conditional E-value: 0.012
  U3_assoc_6  29 rrkfEyklqrrgkkkedflkYieyElnLeklrkkRr 64 
                 r+ +E +++   ++ + ++k++e E  Le+l + R 
  EEA20582.1 456 RTLYEKQIEWNAANSQAWIKFAELERGLEDLERARA 491
                 8899***************************99985 PP

  == domain 6  score: 3.1 bits;  conditional E-value: 0.082
  U3_assoc_6  30 rkfEyklqrrgkkkedflkYieyElnL 56 
                 r+   +l +++ + + +++Y+++E+n+
  EEA20582.1 526 RDLYERLLQKTDHVKVWINYAKFEINI 552
                 5555578889999999*********98 PP

  == domain 7  score: -3.0 bits;  conditional E-value: 6.6
  U3_assoc_6  60 rkkRrk 65 
                 +kkRrk
  EEA20582.1 626 VKKRRK 631
                 333332 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   0.0    0.0097        12      24      81 ..      73     131 ..      61     132 .. 0.83
   2 ?    1.0   0.0      0.43   5.1e+02      58      79 ..     245     266 ..     226     289 .. 0.63
   3 ?   -0.7   0.1       1.5   1.8e+03      37      81 ..     379     428 ..     376     429 .. 0.76
   4 ?   -2.4   0.1       4.7   5.6e+03      38      79 ..     451     493 ..     449     494 .. 0.80
   5 ?   -2.0   0.0       3.7   4.5e+03      37      64 ..     520     547 ..     508     552 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0097
                 HHHHHHHHHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHHH-S CS
      ANAPC3  24 edayllAlclylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaaLek 81 
                 ++ + +A+  ++++++ rA  ++++a + +s+s   ++ + ++  k  +++ A+++L++
  EEA20582.1  73 NNWMRYAQWELEQKEFRRARSIFERAlDVDSTSVVLWIRYIEAEMKTRNINHARNLLDR 131
                 5566699*******************999999998888888888888888888888875 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.43
                 HHHHHHHHHHHTT-HHHHHHHH CS
      ANAPC3  58 crylfAqcllkLkkyeeAiaaL 79 
                 + + +A+   kLk+ye A+a++
  EEA20582.1 245 IFVSYAKFEAKLKEYERARAIY 266
                 3344455555555555555543 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 1.5
                 T-HHHHHHHHHCT.SHHHC-H....HHHHHHHHHHHHTT-HHHHHHHH-S CS
      ANAPC3  37 gqykrAyellrka.klnsksl....gcrylfAqcllkLkkyeeAiaaLek 81 
                 ++  rA ++++++ kl ++ +    ++++ +Aq  + + +++ A+++L+ 
  EEA20582.1 379 KDIGRARQIYQEClKLIPHKKftfaKIWLMKAQFEIRQMELQAARKTLGQ 428
                 66777888888886666666677778999999999999999999999875 PP

  == domain 4  score: -2.4 bits;  conditional E-value: 4.7
                 -HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHHH CS
      ANAPC3  38 qykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaaL 79 
                 +++r+ +l++k  + n  + ++++ fA+    L+ +e A+a++
  EEA20582.1 451 EFNRCRTLYEKQiEWNAANSQAWIKFAELERGLEDLERARAIF 493
                 5889999999999999999999999998877777777777766 PP

  == domain 5  score: -2.0 bits;  conditional E-value: 3.7
                 T-HHHHHHHHHCTSHHHC-HHHHHHHHH CS
      ANAPC3  37 gqykrAyellrkaklnskslgcrylfAq 64 
                 g+y+r  +l++++ ++  + ++++ +A+
  EEA20582.1 520 GEYDRTRDLYERLLQKTDHVKVWINYAK 547
                 8899999999999888888898888886 PP

>> PTS_IIA  PTS system, Lactose/Cellobiose specific IIA subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       3.3   3.9e+03      23      37 ..     116     130 ..      79     145 .. 0.62
   2 ?    3.4   0.0     0.065        77      10      45 ..     381     416 ..     379     429 .. 0.89
   3 ?    4.6   0.4     0.028        34      13      55 ..     575     617 ..     574     625 .. 0.88

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 3.3
     PTS_IIA  23 aakegdfeeaeellk 37 
                 ++k++++++a++ll+
  EEA20582.1 116 EMKTRNINHARNLLD 130
                 345555555555555 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.065
     PTS_IIA  10 aGeArslameAlkaakegdfeeaeellkeAeeelke 45 
                  G Ar+ + e lk + +++f+ a+  l +A+ e+++
  EEA20582.1 381 IGRARQIYQECLKLIPHKKFTFAKIWLMKAQFEIRQ 416
                 699********************9999999988765 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.028
     PTS_IIA  13 ArslameAlkaakegdfeeaeellkeAeeelkeAhkaqteliq 55 
                 Ar+ +  A k +k++d++e +  l +A +++++Ah +  +l +
  EEA20582.1 575 ARKIFERANKVMKDKDLKEERVDLLNAWKAFEQAHGSAEDLAA 617
                 899999999**************************98777655 PP

>> NRDE-2  NRDE-2, necessary for RNA interference
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   1.2     0.021        25      54     132 ..      26      99 ..      10     100 .. 0.70
   2 ?    5.3   3.1    0.0077       9.2       4     110 ..      59     148 ..      56     160 .. 0.64
   3 ?    7.5   4.4    0.0016       1.9       2      59 ..     306     349 ..     305     475 .. 0.54
   4 ?    3.4   1.1     0.029        34      68     111 ..     506     548 ..     454     551 .. 0.50
   5 ?    3.7   3.7     0.024        28       2      66 ..     524     590 ..     523     632 .. 0.68

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.021
      NRDE-2  54 lekAleknksnpdserLllelLklgseiwdseklakeWeellkenpnsvkLWreyldfrqsnfasfsvekvkelyekcl 132
                 l++A+  +++  +  + + e L++ +e +  +  +ke+e++++ n  +++ W++y +++++   + ++ + ++++e++l
  EEA20582.1  26 LREAVDRQEEGVQAPTQRFEDLEELHEYQGRK--RKEFEDYVRRNRINMNNWMRYAQWELE---QKEFRRARSIFERAL 99 
                 55555555444455555555555555555554..59**********************998...556777777777776 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0077
      NRDE-2   4 aelnraveenPedidaWlelvefQdellsaeeeslskserkalaeiklsilekAleknksnpdserLllelLklgseiwdseklakeWeellkenpnsv 102
                 +e++  v++n  +++ W+++++           +     +k+   +  si+e+Al      ++s  L ++++++ +++ + +  ++  ++++   p   
  EEA20582.1  59 KEFEDYVRRNRINMNNWMRYAQWEL--------E-----QKE-FRRARSIFERALDVD---STSVVLWIRYIEAEMKTRNINHARNLLDRAVTILPRVD 140
                 5555555555555555555555554........1.....111.222337777777777...67777777777777777777777777777777777777 PP

      NRDE-2 103 kLWreyld 110
                 kLW +y+ 
  EEA20582.1 141 KLWYKYVY 148
                 77777765 PP

  == domain 3  score: 7.5 bits;  conditional E-value: 0.0016
      NRDE-2   2 knaelnraveenPedidaWlelvefQdellsaeeeslskserkalaeiklsilekAle 59 
                 + ++++++++enP++ d W++++++ ++    + +     + + ++e       +A++
  EEA20582.1 306 RRVQYEEQIKENPRNYDVWFDFARLEETSG--DAD-----RIRDVYE-------RAIA 349
                 667899*******************99433..222.....1222222.......2222 PP

  == domain 4  score: 3.4 bits;  conditional E-value: 0.029
      NRDE-2  68 erLllelLklgseiwdseklakeWeellkenpnsvkLWreyldf 111
                 e +  +++   +++ + +++++ +e+ll++ +++vk+W++y +f
  EEA20582.1 506 ELVWKAYIDFEEYEGEYDRTRDLYERLLQK-TDHVKVWINYAKF 548
                 333344555555555555555556666555.4456666666555 PP

  == domain 5  score: 3.7 bits;  conditional E-value: 0.024
      NRDE-2   2 knaelnraveenPedidaWlelvefQdellsaeee.....slskserkalaeiklsilekAleknksnpd 66 
                 ++++l +++ ++ + ++ W+++++f  ++ + eee     ++  se+++   +  +i+e+A +  k++ d
  EEA20582.1 524 RTRDLYERLLQKTDHVKVWINYAKFEINIPEGEEEeeeeeERPVSEEAKR--RARKIFERANKVMKDK-D 590
                 67888999999999************999977776544433333333333..3345788887777554.2 PP

>> Fis1_TPR_C  Fis1 C-terminal tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.0       1.8   2.1e+03      14      31 ..      85     102 ..      83     103 .. 0.88
   2 ?   -2.4   0.0       4.6   5.4e+03      11      32 ..     116     137 ..     115     139 .. 0.80
   3 ?   -1.6   0.0       2.4   2.9e+03      13      33 ..     185     205 ..     184     208 .. 0.82
   4 ?    5.4   0.1     0.016        20      12      32 ..     254     274 ..     248     284 .. 0.82
   5 ?   -2.0   0.1       3.2   3.8e+03      14      37 ..     449     472 ..     448     473 .. 0.88
   6 ?    1.1   0.1      0.35   4.2e+02      15      30 ..     520     535 ..     519     538 .. 0.93

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 1.8
                 HT-HHHHHHHHHHHHHHT CS
  Fis1_TPR_C  14 lgeYseArryvdalLeiE 31 
                 ++e+++Ar   ++ L ++
  EEA20582.1  85 QKEFRRARSIFERALDVD 102
                 689*********999875 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 4.6
                 HHHHT-HHHHHHHHHHHHHHTT CS
  Fis1_TPR_C  11 hyklgeYseArryvdalLeiEP 32 
                  +k ++ + Ar+++d+   i P
  EEA20582.1 116 EMKTRNINHARNLLDRAVTILP 137
                 578899999*****99877755 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 2.4
                 HHT-HHHHHHHHHHHHHHTTS CS
  Fis1_TPR_C  13 klgeYseArryvdalLeiEPe 33 
                 +  e+++Ar   +++  ++Pe
  EEA20582.1 185 RYNEFDRARAIFQRFTIVHPE 205
                 66899*****99999888876 PP

  == domain 4  score: 5.4 bits;  conditional E-value: 0.016
                 HHHT-HHHHHHHHHHHHHHTT CS
  Fis1_TPR_C  12 yklgeYseArryvdalLeiEP 32 
                 +kl+eY++Ar   +  L   P
  EEA20582.1 254 AKLKEYERARAIYKFALDRLP 274
                 7*********99887776655 PP

  == domain 5  score: -2.0 bits;  conditional E-value: 3.2
                 HT-HHHHHHHHHHHHHHTTS-HHH CS
  Fis1_TPR_C  14 lgeYseArryvdalLeiEPenrQa 37 
                 l e++++r + +  +e    n+Qa
  EEA20582.1 449 LFEFNRCRTLYEKQIEWNAANSQA 472
                 679999999999999999999998 PP

  == domain 6  score: 1.1 bits;  conditional E-value: 0.35
                 T-HHHHHHHHHHHHHH CS
  Fis1_TPR_C  15 geYseArryvdalLei 30 
                 geY++ r + ++lL++
  EEA20582.1 520 GEYDRTRDLYERLLQK 535
                 8*************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (673 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1374  (0.0766356); expected 358.6 (0.02)
Passed bias filter:                      561  (0.0312901); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.75u 0.30s 00:00:01.05 Elapsed: 00:00:00.48
# Mc/sec: 4234.66
//
Query:       EEA20583.1  [L=702]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.4e-06   26.8   9.1      0.004   17.4   0.0    4.1  4  Kelch_6   Kelch motif
  ------ inclusion threshold ------
      0.015   15.3  12.4       0.32   11.0   0.2    4.2  5  Kelch_4   Galactose oxidase, central domain
       0.33   10.4   7.0      0.057   12.9   0.6    2.6  3  Rax2      Cortical protein marker for cell polarity
       0.74    9.4   4.3         14    5.4   0.1    3.7  3  Kelch_1   Kelch motif


Domain annotation for each model (and alignments):
>> Kelch_6  Kelch motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.0   0.4      0.27   1.2e+03       7      17 ..      15      25 ..      14      26 .. 0.89
   2 !   17.4   0.0   8.9e-07     0.004      11      43 ..      65      97 ..      62     101 .. 0.86
   3 ?   -1.9   0.1       1.1   4.8e+03       4      23 ..     108     129 ..     106     138 .. 0.73
   4 !   11.8   0.1   5.3e-05      0.24       5      43 ..     274     308 ..     270     314 .. 0.84

  Alignments for each domain:
  == domain 1  score: -0.0 bits;  conditional E-value: 0.27
     Kelch_6  7 lvsvggkiYif 17
                +v+++++iY++
  EEA20583.1 15 SVVYNNTIYVY 25
                699******96 PP

  == domain 2  score: 17.4 bits;  conditional E-value: 8.9e-07
     Kelch_6 11 gg.kiYifGGytdsspylnkvwvydpetksWeql 43
                ++  +Y++GG t+ ++++  +++y++ +k+We l
  EEA20583.1 65 DNqALYVVGGTTA-DSTYMGLQRYSFANKKWESL 97
                44379********.7888889**********976 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 1.1
     Kelch_6   4 ghslvsvgg..kiYifGGytds 23 
                  hs++   g  +i ++ G++d+
  EEA20583.1 108 NHSAIYLPGtaSILVYAGSNDG 129
                 6888885554779999999986 PP

  == domain 4  score: 11.8 bits;  conditional E-value: 5.3e-05
     Kelch_6   5 hslvs.vggkiYifGGytdsspylnkvwvydpetksWeql 43 
                 +sl+  ++g ++i+GG++      + + v++   +sW  +
  EEA20583.1 274 FSLAQsYNGLVVIAGGSST-----DAITVFNQTQNSWVNT 308
                 5555559**********99.....*************866 PP

>> Kelch_4  Galactose oxidase, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.1         2   9.1e+03       8      18 ..      15      25 ..      14      25 .. 0.73
   2 ?   11.0   0.2   7.2e-05      0.32       5      44 ..      56      97 ..      53     102 .. 0.82
   3 ?    4.2   0.1    0.0099        44       3      24 ..     107     129 ..     107     139 .. 0.83
   4 ?    6.8   0.1    0.0015       6.9       2      29 ..     271     299 ..     270     317 .. 0.80
   5 ?   -3.4   0.1       2.3     1e+04       8      20 ..     343     356 ..     340     357 .. 0.65

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 2
     Kelch_4  8 tsipdgtiylf 18
                 +++++tiy++
  EEA20583.1 15 SVVYNNTIYVY 25
                45688999985 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 7.2e-05
     Kelch_4  5 hsatsi...pdgtiylfGGrgedgtllndlylldlstntWrrl 44
                 + t +   ++  +y++GG ++d +++  l ++++++++W+ l
  EEA20583.1 56 VTGTIDgsaDNQALYVVGGTTAD-STYMGLQRYSFANKKWESL 97
                5666665546689*********9.79999***********976 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.0099
     Kelch_4   3 aghsatsipd.gtiylfGGrged 24 
                 ++hsa+++p+  +i ++ G ++ 
  EEA20583.1 107 VNHSAIYLPGtASILVYAGSNDG 129
                 59******7658********995 PP

  == domain 4  score: 6.8 bits;  conditional E-value: 0.0015
     Kelch_4   2 RaghsatsipdgtiylfGGrgedg.tlln 29 
                 R ++s+ + ++g +++ GG ++d+ t++n
  EEA20583.1 271 RNSFSLAQSYNGLVVIAGGSSTDAiTVFN 299
                 8999999999************9844444 PP

  == domain 5  score: -3.4 bits;  conditional E-value: 2.3
     Kelch_4   8 tsi.pdgtiylfGG 20 
                 ts     t + fGG
  EEA20583.1 343 TSAsATTTAAAFGG 356
                 44425579999999 PP

>> Rax2  Cortical protein marker for cell polarity
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0      0.78   3.5e+03      28      61 ..      60      97 ..      39     109 .. 0.58
   2 ?   -0.2   0.2      0.13   5.7e+02      22      66 ..     269     313 ..     254     323 .. 0.79
   3 ?   12.9   0.6   1.3e-05     0.057     153     196 ..     352     395 ..     325     408 .. 0.75

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 0.78
        Rax2 28 tladsdisqlwvagkssngssfl....lkydgskWssi 61
                +  + d+++l+v g  + +s+++    +++ ++kW+s+
  EEA20583.1 60 IDGSADNQALYVVGGTTADSTYMglqrYSFANKKWESL 97
                44556666677777666666663222234466666665 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.13
        Rax2  22 gpvtsftladsdisqlwvagkssngssfllkydgskWssiddinl 66 
                  + +sf la+s +  +++ag ss +  ++++   ++W ++++  +
  EEA20583.1 269 TTRNSFSLAQSYNGLVVIAGGSSTDAITVFNQTQNSWVNTTKLFY 313
                 466889999999999999999999999999999999999987644 PP

  == domain 3  score: 12.9 bits;  conditional E-value: 1.3e-05
        Rax2 153 lkkkkkklsrgfVVlIgLAlALgtvallgllgiilayirkkreg 196
                    ++ ++s+g+V++  L++ Lg+ a+l +l ++l ++ +k+  
  EEA20583.1 352 AAFGGTRISTGVVIGATLGCLLGVAAILIILLVVLRRFHRKNGT 395
                 3467899****************************998888754 PP

>> Kelch_1  Kelch motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.4     0.058   2.6e+02       5      16 ..      13      24 ..      10      25 .. 0.86
   2 ?    5.4   0.1    0.0031        14      11      42 ..      66      97 ..      63      98 .. 0.83
   3 ?    1.4   0.0     0.055   2.5e+02      10      37 ..     280     303 ..     271     310 .. 0.54

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.058
                EEEEEETTEEEE CS
     Kelch_1  5 agavvvggkiYv 16
                 ++vv ++ iYv
  EEA20583.1 13 RCSVVYNNTIYV 24
                679********9 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.0031
                TTEEEEEEEBCSSSBEEEEEEEETTTTEEEEE CS
     Kelch_1 11 ggkiYviGGsdggnalssvevyDpetntWrel 42
                +  +Yv+GG    +    + +y++ +++W+ l
  EEA20583.1 66 NQALYVVGGTTADSTYMGLQRYSFANKKWESL 97
                6679******9977777889999999999876 PP

  == domain 3  score: 1.4 bits;  conditional E-value: 0.055
                 ETTEEEEEEEBCSSSBEEEEEEEETTTT CS
     Kelch_1  10 vggkiYviGGsdggnalssvevyDpetn 37 
                  +g + + GGs+    ++ + v++ ++n
  EEA20583.1 280 YNGLVVIAGGSS----TDAITVFNQTQN 303
                 455556666655....344444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (702 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       619  (0.0345251); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.65u 0.30s 00:00:00.95 Elapsed: 00:00:00.46
# Mc/sec: 4542.38
//
Query:       EEA20584.1  [L=269]
Description: short chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.6e-29  102.8   0.0      3e-21   75.8   0.0    2.0  2  adh_short     short chain dehydrogenase
    3.8e-20   72.4   0.0    2.9e-13   49.9   0.0    2.0  2  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
    9.5e-05   22.4   0.0    0.00015   21.7   0.0    1.2  1  KR            KR domain


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.8   0.0   5.1e-25     3e-21       1     140 [.       3     155 ..       3     164 .. 0.89
   2 !   25.1   0.0   1.7e-09     1e-05     141     187 ..     178     224 ..     173     228 .. 0.92

  Alignments for each domain:
  == domain 1  score: 75.8 bits;  conditional E-value: 5.1e-25
                 SEEEEESTTSHHHHHHHHHHH...HTT-EEEEEESCHHHHHHHHHHHHHT.....TSEEEEEE-TTTSHHHHHHHHHHHHHHH.SSESEEEE---S... CS
   adh_short   1 kvvlvtGassGIGraiakela...keGakvvvvdrseekleevakelkee.....gakalaiqvDvtdreevealvekavkkl.gkldvLvnNAGi... 87 
                 k v++tGa  GIG +i+++l+   ke +++++ +rs ++++++++ +k+e      +++++iq+D++d +++ a+++++  +l gkldvL+nNAG    
  EEA20584.1   3 KSVFITGANTGIGFQIVRALYgssKESYQILLGSRSLSNAHNAIEAVKSEfpsspTSSLTPIQIDIEDDDSIAAAYNAISTQLdGKLDVLINNAGAqle 101
                 679****************964448899999999999999999999998888767678**************************************997 PP

                 S--SSGGGCSHHH.HHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGT CS
   adh_short  88 tgsgpfselseee.wervievNltgvflltravlpamlkqssGrIvnvsSvagk 140
                 +g ++ +  se+e w+++ ++N t++  +t  ++p +l++s  r  +++S ++ 
  EEA20584.1 102 HGLAQGKIASERElWDKSWSINTTSTQVVTSKFVPLLLQSSDPRLLFITSGTSA 155
                 66666666777779************************************9874 PP

  == domain 2  score: 25.1 bits;  conditional E-value: 1.7e-09
                 SB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHH CS
   adh_short 141 vpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdma 187
                  ++ gv+aY ++K ++++l+r++ + l+ +g++v a+ PG+++T++ 
  EEA20584.1 178 TGFMGVPAYRSAKTGLNMLMREWYRILKGDGVKVFAISPGFLATGLG 224
                 578899**************************************875 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.9   0.0   4.8e-17   2.9e-13       1     134 [.       9     157 ..       9     169 .. 0.86
   2 !   20.8   0.0   3.9e-08   0.00024     135     183 ..     180     228 ..     161     241 .. 0.85

  Alignments for each domain:
  == domain 1  score: 49.9 bits;  conditional E-value: 4.8e-17
                   TTTTSHHHHHHHHH...HHTT-EEEEEESSGGH.HHHHHHHHHHTTSE.E.....EE--TTSHHHHHHHHHHHHHHH.SSEEEEEE-----EG..CS CS
  adh_short_C2   1 GaasgIGraiAkal...aeeGaevvltdlneea.kkrveelaeelgae.v.....lecDVtdeeqvealveevvekf.gklDilvnnagiapk..lk 84 
                   Ga  gIG++i++al    +e ++++l  ++ ++ ++++e++++e++++       +++D++d+++++a+ +++  ++ gklD+l+nnag   +  l 
    EEA20584.1   9 GANTGIGFQIVRALygsSKESYQILLGSRSLSNaHNAIEAVKSEFPSSpTssltpIQIDIEDDDSIAAAYNAISTQLdGKLDVLINNAGAQLEhgLA 105
                   8899*********9444589999***9999999899*********9665235689************************************999988 PP

                   S-GGGH-HHHHHHHHHHHTHHHHHHHHHHHH.HCTSC.CEEEEEEEGGGTSB CS
  adh_short_C2  85 gpfletsreefdraldvnlyslfllakaalp.lmkeg.gsivnlssvgaerv 134
                   +  +  +re +d+  ++n++s+  ++  ++p l++++  +++ ++s  +  +
    EEA20584.1 106 QGKIASERELWDKSWSINTTSTQVVTSKFVPlLLQSSdPRLLFITSGTSAFA 157
                   888999*************************655555788888888766554 PP

  == domain 2  score: 20.8 bits;  conditional E-value: 3.9e-08
                   STTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGST CS
  adh_short_C2 135 vpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgik 183
                   + +  ay  aK +l+ l+r + + l  +g++v a+spg+++T +  + +
    EEA20584.1 180 FMGVPAYRSAKTGLNMLMREWYRILKGDGVKVFAISPGFLATGLGGDTE 228
                   4456699**********************************99876654 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.7   0.0   2.6e-08   0.00015       3      92 ..       5      99 ..       4     116 .. 0.78

  Alignments for each domain:
  == domain 1  score: 21.7 bits;  conditional E-value: 2.6e-08
                EEEETTTSHHHHHHHHHHHHHH..S-EEEEE-SS...--HHHHHHHHHHHHT.T-EEEE----TT-HHHHHHHHHHHHHHS.S---EEEE----- CS
          KR  3 ylitGGlGgLGlelarwlaekg..arhlvllsRsa.aadedskaliaeleal.gaevevvaaDvsdkdavealleeikaee.ppikGvihaAgvl 92
                ++itG+  g+G +++r l+ +     +++l sRs  +a+++ +a  +e+ ++   + + +++D+ d d+++a+ ++i+++  +++   i+ Ag+ 
  EEA20584.1  5 VFITGANTGIGFQIVRALYGSSkeSYQILLGSRSLsNAHNAIEAVKSEFPSSpTSSLTPIQIDIEDDDSIAAAYNAISTQLdGKLDVLINNAGAQ 99
                68*****************8774356788889984233333334444555554779**********************99989999999999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (269 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       253  (0.0141112); expected 358.6 (0.02)
Passed bias filter:                      235  (0.0131073); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.48
# Mc/sec: 1674.02
//
Query:       EEA20585.1  [L=327]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-05   24.5   0.0    5.3e-05   23.2   0.0    1.7  1  SRR1      SRR1


Domain annotation for each model (and alignments):
>> SRR1  SRR1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.2   0.0     3e-09   5.3e-05       1      52 [.     156     217 ..     156     219 .. 0.79

  Alignments for each domain:
  == domain 1  score: 23.2 bits;  conditional E-value: 3e-09
        SRR1   1 ivclGLGsfse........sssaryQLAlllelveelkiessrs..vyaqDPvftevDkalL 52 
                 i+++G Gs+           +    Q++++ e++e +k++ +++  +yaq+P +t++D+++L
  EEA20585.1 156 IIAFGNGSLWYgwkkepglIRDFVAQHSVIQEIREFIKKTCNQEvaCYAQEPKYTPADEKVL 217
                 5667777777655544433333348****************999***************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (327 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       741  (0.0413297); expected 358.6 (0.02)
Passed bias filter:                      602  (0.0335769); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2226.60
//
Query:       EEA20586.1  [L=207]
Description: C2H2 transcription factor (Egr2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    8.3e-07   29.1  11.7    6.3e-05   23.2   4.0    2.9  2  zf-C2H2    Zinc finger, C2H2 type
    1.9e-06   28.0  17.2      7e-06   26.2   2.8    3.8  3  zf-H2C2_2  Zinc-finger double domain
    0.00028   20.8   0.8    0.00028   20.8   0.8    2.5  3  zf-C2H2_6  C2H2-type zinc finger
    0.00066   20.0   8.9     0.0024   18.2   0.6    2.5  2  zf-met     Zinc-finger of C2H2 type
      0.001   19.7   2.1      0.001   19.7   2.1    3.3  3  zf-C2H2_4  C2H2-type zinc finger
     0.0068   16.1   0.3      0.013   15.2   0.3    1.4  1  DUF2225    Uncharacterized protein conserved in bacteria (DUF
  ------ inclusion threshold ------
       0.01   16.1   4.8       0.01   16.1   4.8    1.8  2  zf-Di19    Drought induced 19 protein (Di19), zinc-binding
        8.9    6.1   7.0         21    4.9   6.9    1.7  1  MCPVI      Minor capsid protein VI


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.9    0.0006       1.3       1      23 []     137     164 ..     137     164 .. 0.90
   2 !   23.2   4.0   2.8e-08   6.3e-05       3      23 .]     172     192 ..     171     192 .. 0.98

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0006
                 EEET.....TTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCp.....dCgksFkrksnLkrHirtH 23 
                 y+Cp      C+ +F+++ +  rH ++H
  EEA20586.1 137 YPCPyaashACTATFTTSGHAARHGKKH 164
                 6778777778***************999 PP

  == domain 2  score: 23.2 bits;  conditional E-value: 2.8e-08
                 ETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   3 CpdCgksFkrksnLkrHirtH 23 
                 Cp+C+k F+rk+n+k+H+rtH
  EEA20586.1 172 CPVCNKAFTRKDNMKQHRRTH 192
                 ********************9 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.5   1.1    0.0055        12       6      26 .]     128     153 ..     128     153 .. 0.83
   2 !   26.2   2.8   3.1e-09     7e-06       4      26 .]     159     181 ..     158     181 .. 0.94
   3 ?    3.6   0.4     0.045     1e+02       1      13 [.     184     196 ..     184     198 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0055
   zf-H2C2_2   6 irkHtgekpyeCp.....lCdkaFkt 26 
                 ++k t++++y Cp     +C  +F+t
  EEA20586.1 128 MAKTTKKNKYPCPyaashACTATFTT 153
                 567799*******8888888888875 PP

  == domain 2  score: 26.2 bits;  conditional E-value: 3.1e-09
   zf-H2C2_2   4 rHirkHtgekpyeCplCdkaFkt 26 
                 rH +kHtgek ++Cp+C+kaF++
  EEA20586.1 159 RHGKKHTGEKSVHCPVCNKAFTR 181
                 8889*****************85 PP

  == domain 3  score: 3.6 bits;  conditional E-value: 0.045
   zf-H2C2_2   1 nLrrHirkHtgek 13 
                 n ++H r+H++++
  EEA20586.1 184 NMKQHRRTHRSPT 196
                 6789*****9986 PP

>> zf-C2H2_6  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.7   0.8         8   1.8e+04      23      26 ..      94      97 ..      93      97 .. 0.63
   2 ?   -3.5   0.0       5.2   1.2e+04       7      13 ..     147     153 ..     146     153 .. 0.84
   3 !   20.8   0.8   1.3e-07   0.00028       4      26 ..     172     194 ..     171     195 .. 0.96

  Alignments for each domain:
  == domain 1  score: -4.7 bits;  conditional E-value: 8
   zf-C2H2_6 23 sHrk 26
                +H++
  EEA20586.1 94 QHHR 97
                7875 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 5.2
   zf-C2H2_6   7 CsksFps 13 
                 C ++F +
  EEA20586.1 147 CTATFTT 153
                 9999986 PP

  == domain 3  score: 20.8 bits;  conditional E-value: 1.3e-07
   zf-C2H2_6   4 CsvCsksFpslqaLggHkksHrk 26 
                 C+vC+k F   +++  H+++Hr+
  EEA20586.1 172 CPVCNKAFTRKDNMKQHRRTHRS 194
                 **********************8 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   2.2     0.011        24       5      25 .]     146     164 ..     145     164 .. 0.95
   2 !   18.2   0.6   1.1e-06    0.0024       2      21 ..     171     190 ..     170     193 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.011
      zf-met   5 lCnvtfnsesqlksHlqGKkH 25 
                 +C  tf+  +++  H  GKkH
  EEA20586.1 146 ACTATFTTSGHAARH--GKKH 164
                 6999***********..**** PP

  == domain 2  score: 18.2 bits;  conditional E-value: 1.1e-06
      zf-met   2 yCelCnvtfnsesqlksHlq 21 
                 +C++Cn+ f+ + ++k+H +
  EEA20586.1 171 HCPVCNKAFTRKDNMKQHRR 190
                 7*****************66 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   3.3         8   1.8e+04      10      20 ..      77      86 ..      74      90 .. 0.56
   2 ?    5.2   0.6     0.021        46       1      19 [.     137     160 ..     137     165 .. 0.81
   3 !   19.7   2.1   4.7e-07     0.001       2      23 ..     171     192 ..     170     193 .. 0.95

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 8
   zf-C2H2_4 10 FsskkaLlrHl 20
                +ss+++  +H 
  EEA20586.1 77 YSSQHH-HHHQ 86
                545544.6665 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.021
   zf-C2H2_4   1 fkCpi.....CgksFsskkaLlrH 19 
                 ++Cp+     C+++F+++ +  rH
  EEA20586.1 137 YPCPYaashaCTATFTTSGHAARH 160
                 7899999999*****998876667 PP

  == domain 3  score: 19.7 bits;  conditional E-value: 4.7e-07
   zf-C2H2_4   2 kCpiCgksFsskkaLlrHlkth 23 
                  Cp+C+k F++k+++++H +th
  EEA20586.1 171 HCPVCNKAFTRKDNMKQHRRTH 192
                 6********************9 PP

>> DUF2225  Uncharacterized protein conserved in bacteria (DUF2225)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.3   5.9e-06     0.013       3      33 ..     167     197 ..     166     201 .. 0.86

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 5.9e-06
     DUF2225   3 kkkieCPvCeekfkkkkvkssslrlikrdsd 33 
                 +k+++CPvC++ f++k   +++ r+ +  +d
  EEA20586.1 167 EKSVHCPVCNKAFTRKDNMKQHRRTHRSPTD 197
                 699************9998889998887776 PP

>> zf-Di19  Drought induced 19 protein (Di19), zinc-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -6.1   4.3         8   1.8e+04      20      25 ..      84      89 ..      76      99 .. 0.50
   2 ?   16.1   4.8   4.6e-06      0.01       2      49 ..     136     189 ..     135     194 .. 0.74

  Alignments for each domain:
  == domain 1  score: -6.1 bits;  conditional E-value: 8
     zf-Di19 20 HvedeH 25
                H + +H
  EEA20586.1 84 HHQPQH 89
                333333 PP

  == domain 2  score: 16.1 bits;  conditional E-value: 4.6e-06
     zf-Di19   2 sftCPy.....CgkeltvkeLveHvedeHrveskevvCPvCaekvtk..dlvaHl 49 
                 +++CPy     C+ ++t++   +   ++H+ e k+v CPvC +  t+  ++ +H 
  EEA20586.1 136 KYPCPYaashaCTATFTTSGHAARHGKKHTGE-KSVHCPVCNKAFTRkdNMKQHR 189
                 799***77777777788887777777888876.5799****98865334898885 PP

>> MCPVI  Minor capsid protein VI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   6.9    0.0093        21     164     195 ..      95     136 ..      34     152 .. 0.72

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.0093
                 X..........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       MCPVI 164 d..........evkkPvlssesavvvsrPsrlelrraaskrr 195
                            + + P++ss+sa ++  Ps+ e+ +++ k++
  EEA20586.1  95 HhrtpsiqsnsDLSSPSISSPSAAAFYAPSTTEMAKTTKKNK 136
                 04444444555999********************99988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (207 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1048  (0.0584528); expected 358.6 (0.02)
Passed bias filter:                      446  (0.0248759); expected 358.6 (0.02)
Passed Vit filter:                        69  (0.00384851); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.51u 0.30s 00:00:00.81 Elapsed: 00:00:00.47
# Mc/sec: 1316.48
//
Query:       EEA20587.1  [L=438]
Description: UPF0261 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.4e-166  554.5   1.2   1.6e-166  554.3   1.2    1.0  1  UPF0261   Uncharacterised protein family (UPF0261)


Domain annotation for each model (and alignments):
>> UPF0261  Uncharacterised protein family (UPF0261)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  554.3   1.2  8.9e-171  1.6e-166       1     403 [.       4     422 ..       4     423 .. 0.96

  Alignments for each domain:
  == domain 1  score: 554.3 bits;  conditional E-value: 8.9e-171
     UPF0261   1 ktvlligtlDTKleellflrelieeeg.vevlliDvgtree.ekeaidisreevleaagkeaeeelesldrgeaieamseaaaklvkely.eekidgvi 96 
                 ++++++gt+DTKl+e+lflr++i +++ vevll+Dvg r++ ++++id+++ e++ +++++  + l++ +r+e+i++m+e+a+++v+el+  ++i+g+i
  EEA20587.1   4 PRIAVLGTCDTKLAEMLFLRDQIIRTKeVEVLLLDVG-RNPvQNSHIDVPSFELALRKSADGPSALTQMSRAEYIKYMIECATSYVTELFqLGEIHGII 101
                 589*****************99877666*********.555599***********9999998889*************************6666***** PP

     UPF0261  97 slGGsggtslataamr.alpiGlPKlivSTvAsgdvspyvgesDitlmysvvDiaGlNsilrkvLsnAaaaiaGmakaeekskeek.....eeeeekpl 189
                 s+ Gs+gtsl+ta+mr alp+G+PK++vST+Asgdvs++v+e+DitlmysvvDiaG+N il+++L+nAaaai+G+a+a+ +s++e       +++++++
  EEA20587.1 102 SAAGSSGTSLVTAVMRnALPVGFPKFMVSTMASGDVSHLVEETDITLMYSVVDIAGTNFILNQILTNAAAAITGAATAYYRSRNEGasgnaGAKQRRQR 200
                 ********************************************************************************987766999999999**** PP

     UPF0261 190 vaitmfGvttpavdairelLee.egyevlvFhAtGtGGramErLireglldavlDltttEladelvggvlsagpdRleaaaekgiPqvvsvGalDmvnf 287
                 vaitmfGvttp+vdair++Le+  gyev+vFhAtG+GG+amErLireg++davlD+tttE+adel+ggvlsagp+Rl+aaa++giPq+vsvGa+Dmvnf
  EEA20587.1 201 VAITMFGVTTPCVDAIRKHLESkYGYEVYVFHATGAGGKAMERLIREGQIDAVLDMTTTEIADELIGGVLSAGPQRLTAAAQAGIPQIVSVGACDMVNF 299
                 *********************9679************************************************************************** PP

     UPF0261 288 galetvpekfk....grklyehnpqvtlvrtsaeenrelgefiaeklnkakgp...vrvllPkkGvsaldaeggpfedpeadealfealeeelkeseie 379
                 g+++tvp++f+    +r lyehnp+vtl+rt+a+e+++++efia+kl++++ +   v+vllP+ G+s+++++ +pf+ p++d+alf+++e++l++s++e
  EEA20587.1 300 GPRDTVPAEFAssenKRLLYEHNPAVTLMRTTAQECTRIAEFIASKLRDHAVRsdlVKVLLPTSGISMISTPSQPFYMPDSDAALFDTMERQLEGSGVE 398
                 **********555559*******************************999888889******************************************* PP

     UPF0261 380 vvevdahindeeFaeavaeallel 403
                 v+++d++ind++Fa ++ae l+e+
  EEA20587.1 399 VRRDDREINDKGFALSAAELLVEV 422
                 *******************99986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (438 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       389  (0.0216967); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2919.98
//
Query:       EEA20588.1  [L=280]
Description: TIM-barrel enzyme family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   2.5e-134  446.6   0.3   2.9e-134  446.4   0.3    1.0  1  PEP_hydrolase  Phosphoenolpyruvate hydrolase-like
  ------ inclusion threshold ------
      0.017   14.5   0.1      0.024   14.0   0.1    1.2  1  NMO            Nitronate monooxygenase


Domain annotation for each model (and alignments):
>> PEP_hydrolase  Phosphoenolpyruvate hydrolase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  446.4   0.3  3.2e-138  2.9e-134       2     267 .]      10     275 ..       9     275 .. 0.99

  Alignments for each domain:
  == domain 1  score: 446.4 bits;  conditional E-value: 3.2e-138
  PEP_hydrolase   2 ilkrlrkkikkgkpiigagaGtGlsakaaeaggaDliliynsGrfrmaGrgslagllpygnaNeivvemakevlpvvketpvlaGvcatDpfrkle 97 
                    il rlrk i++g +i+gagaG+Glsak++e+gg Dli+iynsGrfrmaGrgslagl+py++aN++vv+make+lp+vk+tpvlaGvc+tDpfr+++
     EEA20588.1  10 ILVRLRKVISDGGIIVGAGAGIGLSAKSEEQGGSDLIIIYNSGRFRMAGRGSLAGLMPYSDANAVVVDMAKEILPIVKQTPVLAGVCGTDPFREMP 105
                    899********************************************************************************************* PP

  PEP_hydrolase  98 eflkelkelGfaGvqNfPtvglidgefrenleetglgyekEvelikkAheldllttayvfneeearamaeaGadvivahlGlttggsigaktalsl 193
                    efl +lkelGf+G+qNfPtvglidg+fr+nleetg+gy+kEve+++ A+e+d++tt+yvfn +ea++m++aGadv+vah+Gltt+gsiga+ta sl
     EEA20588.1 106 EFLGQLKELGFSGIQNFPTVGLIDGKFRQNLEETGMGYDKEVEMVRIAREMDIFTTPYVFNVDEAERMVRAGADVLVAHVGLTTSGSIGAETAFSL 201
                    ************************************************************************************************ PP

  PEP_hydrolase 194 eeavelvqeiadaakevnpdvivlvhGGpiaepedaeyvlertkgvkGfigassleRlpvekaikettkeFksl 267
                    ++av++vq+i+d a ++npd+ivl+hGGpiaep+daeyvl++tkg++Gf+gass+eRlpve aike++++Fk+l
     EEA20588.1 202 DDAVKIVQDIRDSAVRINPDIIVLCHGGPIAEPKDAEYVLNHTKGIHGFFGASSMERLPVEIAIKENAQAFKNL 275
                    ************************************************************************85 PP

>> NMO  Nitronate monooxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.1   2.6e-06     0.024     124     201 ..     145     229 ..     118     243 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 2.6e-06
         NMO 124 pteevvarlkeagvvliptissvkearkvearGaDalivq.GpeaGGhqGtpevgd..kglfaLvpqvld.avd....iPviAaGG 201
                 ++ e+v    e++++  p +  v+ea  + ++GaD+l++  G    G +G  e++    + +++v+ ++d av     i v+  GG
  EEA20588.1 145 KEVEMVRIAREMDIFTTPYVFNVDEAERMVRAGADVLVAHvGLTTSGSIG-AETAFslDDAVKIVQDIRDsAVRinpdIIVLCHGG 229
                 446777788999**************************97699999****.33332346777777777762343555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (280 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       339  (0.0189079); expected 358.6 (0.02)
Passed bias filter:                      302  (0.0168442); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.41
# Mc/sec: 2059.33
//
Query:       EEA20589.1  [L=579]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (579 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       901  (0.0502538); expected 358.6 (0.02)
Passed bias filter:                      303  (0.0169); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.63u 0.27s 00:00:00.90 Elapsed: 00:00:00.42
# Mc/sec: 4129.89
//
Query:       EEA20590.1  [L=246]
Description: hypothetical protein PMAA_044230 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.11   12.8   0.2          3    8.2   0.0    2.9  3  DinI      DinI-like family


Domain annotation for each model (and alignments):
>> DinI  DinI-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   0.0   0.00017         3      23      60 ..      67     103 ..      61     106 .. 0.84
   2 ?   -0.0   0.0     0.063   1.1e+03      24      54 ..     105     133 ..     103     135 .. 0.79
   3 ?    0.3   0.1     0.052   9.3e+02      15      36 ..     203     226 ..     192     242 .. 0.52

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.00017
                 -EEEEEEESS-EEEEES--HHHHHHHHHHHHHHHHTHH CS
        DinI  23 aevrvrkasanglsveGaskedkeriseiLQetwesAD 60 
                   + ++  +  +l+++ + k++ ++i e LQe +++A 
  EEA20590.1  67 RVIAIQNRGYAELKAS-GGKTEADLIVEELQELYDNAK 103
                 5678889999999999.678999************986 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 0.063
                 EEEEEEESS-EEEEES--HHHHHHHHHHHHH CS
        DinI  24 evrvrkasanglsveGaskedkeriseiLQe 54 
                 e++++ +s+ng ++   + +d+e   e+L +
  EEA20590.1 105 EFEIATDSTNGATIY--AASDRESARELLDQ 133
                 678999999999998..77788888887765 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.052
                 HHHHH-SS..-EEEEEEESS-EEE CS
        DinI  15 RiqevfPd..aevrvrkasangls 36 
                 Ri + f    ++v+v++  ++ + 
  EEA20590.1 203 RIAPTFDPeyISVEVKEEVKKRVG 226
                 566666332555555555444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (246 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       981  (0.0547158); expected 358.6 (0.02)
Passed bias filter:                      637  (0.035529); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 1698.72
//
Query:       EEA20591.1  [L=438]
Description: alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.4e-17   61.4   0.4    1.6e-16   60.1   0.4    1.7  1  ADH_N            Alcohol dehydrogenase GroES-like domain
    2.3e-12   47.0   0.0    3.6e-12   46.4   0.0    1.3  1  ADH_zinc_N       Zinc-binding dehydrogenase
  ------ inclusion threshold ------
      0.064   13.9   0.1       0.24   12.1   0.1    2.0  1  Methyltransf_11  Methyltransferase domain


Domain annotation for each model (and alignments):
>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.1   0.4   2.7e-20   1.6e-16       3     107 ..      94     213 ..      92     215 .. 0.79

  Alignments for each domain:
  == domain 1  score: 60.1 bits;  conditional E-value: 2.7e-20
                 EEEEEEEEEEE-HHHHHHHTTS..TTTTSSSSEE---EEEEEEEEESTT-CS..--TT-EEEE..-SEEE-SSSHHHHTT-GGG-.........TTBEE CS
       ADH_N   3 evlikvkaagiCgsDlhilkgg..kelevklplilGHEivGeveevgpevkk..lkvGdrVvv..epliscgeCaaCkegeenlC.........eeakl 86 
                 ++l++v aa+ C++D+ +++g+  +  +  +p +  HE++G+++++ p+  +  +++GdrV v   p  +cgeCa+C e+++            ++ k 
  EEA20591.1  94 DLLVRVDAASYCHTDYVLASGHmaSVEQPVFPHTGCHEFTGTIVALPPRPAQsdFTIGDRVGVscRPYHACGECAECLEENTPDSdprgysvlcPTIKS 192
                 689*****************9643333444568999*********986655555******9984456788*******98765433344444444***** PP

                 TTTSS-SSSBSEEEECGGGEE CS
       ADH_N  87 lgvsldGgfaeyvvvpekklv 107
                 +g++++Ggf+eyv+v++++l 
  EEA20591.1 193 HGIGIPGGFQEYVLVDSRQLT 213
                 ****************99875 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.4   0.0   6.1e-16   3.6e-12       1     128 [.     257     394 ..     257     396 .. 0.91

  Alignments for each domain:
  == domain 1  score: 46.4 bits;  conditional E-value: 6.1e-16
                 HHHHHHHHHHHHTT-EEEEEESSHHHHHHHHHT....TESEEEETTTC.HHHHHHHHHT........TTSSEEEEEESSCSHHHHHHHHHCEEEEEEEE CS
  ADH_zinc_N   1 gvGlaavqlAkalGaeviavdsseeklelakkl....Gadevinykea.dlverikelt........ggegvdvvfecvGsgatleaalkllkpgGrlv 86 
                 g+G++++q+A a+G +v++v  s++ l+la+ l    Ga+ +i++ ++ +  e+i+ +         g+ g+d+v+  + s+++++  +++lk +G++v
  EEA20591.1 257 GLGHLGLQYATAMGLRVYGVENSDKPLALARGLknipGAT-IIDS-RTtTAAEAIAHIStedkrpipGQFGLDAVIILPESQRAFQYGVDMLKNHGKCV 353
                 89******************************99999977.5666.344888888888789999999999***************************** PP

                 ECSCTSSEEEEEHHHHHHTT-EEEEE-SSCHHHHHHHHHHHH CS
  ADH_zinc_N  87 vvGggkgeeefdlrnlllkeksilGsllgslreefkealdll 128
                 vv ++ ++ + +  +l++++++ +G + gs +++++e+ ++ 
  EEA20591.1 354 VVSFPPDGFHTSSLDLIFRDITYVGNVSGS-TKQLREMTAFS 394
                 ****999999********************.99999988876 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.1     4e-05      0.24       3      44 ..     252     301 ..     251     354 .. 0.70

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 4e-05
                      ET-TTSHHHHHHH...HTTSEEEEEES-HHHHHHHHHHCCHHT-.....E CS
  Methyltransf_11   3 vGcGtGrlaeala...krgarvvgvDlskemlklakekaseegl.....k 44 
                      +GcG+G+    l+     g rv+gv+ s++ l+la+  ++ +g      +
       EEA20591.1 252 IGCGGGLGHLGLQyatAMGLRVYGVENSDKPLALARGLKNIPGAtiidsR 301
                      7******999999765666****************988887775545443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (438 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.61u 0.34s 00:00:00.95 Elapsed: 00:00:00.55
# Mc/sec: 2419.26
//
Query:       EEA20592.1  [L=293]
Description: 3-oxoacyl-(acyl-carrier-protein) reductase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.3e-43  147.0   0.0    4.9e-37  127.7   0.0    2.0  2  adh_short_C2   Enoyl-(Acyl carrier protein) reductase
    7.6e-41  139.7   0.0      1e-40  139.3   0.0    1.1  1  adh_short      short chain dehydrogenase
    1.7e-14   54.2   0.0    2.8e-14   53.4   0.0    1.3  1  KR             KR domain
    6.5e-06   25.8   0.1    0.00014   21.4   0.1    2.1  1  Epimerase      NAD dependent epimerase/dehydratase family
     0.0015   18.0   0.0      0.022   14.1   0.0    2.0  2  GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
  ------ inclusion threshold ------
       0.07   13.1   0.0       0.12   12.3   0.0    1.4  1  Gag_p17        gag gene protein p17 (matrix protein)


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.7   0.0   1.7e-40   4.9e-37       3     201 ..      16     230 ..      10     240 .. 0.84
   2 !   17.8   0.1   6.5e-07    0.0019     194     233 ..     250     289 ..     232     290 .. 0.83

  Alignments for each domain:
  == domain 1  score: 127.7 bits;  conditional E-value: 1.7e-40
                   TTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSE..E....EE--TTSHHHHHHHH.HHHHHHHS....SEEEEEE-----EG..CSS- CS
  adh_short_C2   3 asgIGraiAkalaeeGaevvltdlneeakkrveelaeelgae..v....lecDVtdeeqvealv.eevvekfg....klDilvnnagiapk..lkgp 86 
                    +gIG+aiA+ la++G++++l + +e+++ ++eela+++ ++  v    +++D td ++  +++ ++ +++fg    ++Dil+nnag++++  l  +
    EEA20592.1  16 SRGIGEAIARNLAKKGCSLLLNYTSESSRTKTEELASSFTESfgVhcttVRADLTDAQAASEIIiDASKKHFGdkplRIDILINNAGVSQDrkLADS 112
                   49**********************************999977443667899*****9998887615556666544448*************863333 PP

                   GGG.H-HHHHHHHHHHHTHHHHHHHHHHHHHCTSC..CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTG.G CS
  adh_short_C2  87 fle.tsreefdraldvnlyslfllakaalplmkeg..gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTla.a 179
                   +   ++ e f+   ++n+ + +ll++a++p++ +   g+ivn+ssv+++ +++++++yg +Kaalea+tr++A+el++ + +vNav pgp+  ++  
    EEA20592.1 113 AKGpIDAEYFHWHYNINVLAPLLLTQACIPYLPNDrsGRIVNISSVSSSLGFEGQSVYGGTKAALEAMTRTWARELAD-RATVNAVNPGPVIGDMyF 208
                   3334899***********************7776669****************************************9.99**********999843 PP

                   GGSTTHHHHHHHHHHHSTTSS- CS
  adh_short_C2 180 sgikgfdelleelearaplgrl 201
                      ++f + ++ +++++pl ++
    EEA20592.1 209 LTGEQFWKDIQGWQDNTPLSKV 230
                   3333477778888888888775 PP

  == domain 2  score: 17.8 bits;  conditional E-value: 6.5e-07
                   HHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEESTTG CS
  adh_short_C2 194 araplgrlgtpeevaeaalfLasdeasyitGqtlvvDgGl 233
                   ++   +r + ++e+a ++++L+ ++a+++tG+++ ++gG+
    EEA20592.1 250 EKMGGRRPAFTSEIAGVVAMLCTEDAAWCTGSVVNANGGM 289
                   555556778899***************************8 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.3   0.0   3.4e-44     1e-40       4     186 ..      11     206 ..       8     211 .. 0.88

  Alignments for each domain:
  == domain 1  score: 139.3 bits;  conditional E-value: 3.4e-44
                 EEESTTSHHHHHHHHHHHHTT-EEEE...EESCHHHHHHHHHHHHHT.TSEEEEEE-TTTSHHHHHHHHHHHHHHH.....SSESEEEE---SS--SSG CS
   adh_short   4 lvtGassGIGraiakelakeGakvvv...vdrseekleevakelkee.gakalaiqvDvtdreevealvekavkkl.....gkldvLvnNAGitgsgpf 93 
                 +vtG+s+GIG aia++lak+G+++++    ++s  k ee+a+++ e  g + +++++D+td++++++++ +a kk+      ++d+L+nNAG++++++ 
  EEA20592.1  11 IVTGGSRGIGEAIARNLAKKGCSLLLnytSESSRTKTEELASSFTESfGVHCTTVRADLTDAQAASEIIIDASKKHfgdkpLRIDILINNAGVSQDRKL 109
                 8***********************99732234556789999999999**************9999999888877777887779**********777777 PP

                 GGCSHHHHHHH.....HHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHH CS
   adh_short  94 selseeewerv.....ievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdm 186
                 ++  +  +++      +++N+ +++llt+a++p++ + +sGrIvn+sSv +  +++g+++Y+ +Kaa++++tr++a+ela++  +vnav+PG+v  dm
  EEA20592.1 110 ADSAKGPIDAEyfhwhYNINVLAPLLLTQACIPYLPNDRSGRIVNISSVSSSLGFEGQSVYGGTKAALEAMTRTWARELADR-ATVNAVNPGPVIGDM 206
                 7665554544444444*****************************************************************8.9********997666 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.4   0.0   9.4e-18   2.8e-14       4     171 ..      11     192 ..       9     202 .. 0.82

  Alignments for each domain:
  == domain 1  score: 53.4 bits;  conditional E-value: 9.4e-18
                 EEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHT.T-EEEE----TT-HHHHHHHHHHHHHHS.....S---EEEE--------- CS
          KR   4 litGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaeleal.gaevevvaaDvsdkdavealleeikaee.....ppikGvihaAgvlrdkl 96 
                 ++tGG  g+G ++ar la+kg + l+  + + +++ + ++l ++++++ g+++++v+aD++d++a ++++ ++++++      +i   i+ Agv++d++
  EEA20592.1  11 IVTGGSRGIGEAIARNLAKKGCSLLLNYTSE-SSRTKTEELASSFTESfGVHCTTVRADLTDAQAASEIIIDASKKHfgdkpLRIDILINNAGVSQDRK 108
                 79*******************8877766655.35666666777766655*******************98887777667733356789*********** PP

                 TTT.....--HHHHHHHHTTTTHHHHHHHHHTTT....S--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHHHHHTEE CS
          KR  97 lee.....mtaedleqvlapKvkGawnLhelled....esldffvlfSSiagllgsagqanYaaaNaflDalaeyrrsqglpav 171
                 l++      +ae ++  ++  v +   L +++ +    ++   +v +SS+++ lg  gq+ Y  + a l+a+ ++++++ +   
  EEA20592.1 109 LADsakgpIDAEYFHWHYNINVLAPLLLTQACIPylpnDRSGRIVNISSVSSSLGFEGQSVYGGTKAALEAMTRTWARELADRA 192
                 *98333334778899999************9877666688889******************************99988765544 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.1   4.6e-08   0.00014       2      60 ..      11      79 ..      11     206 .. 0.77

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 4.6e-08
                EEETTTSHHHHHHHHHHHHCTSE.EEEEES-STTTTCHHCHHC.........EEEE--TT-HHHHHHHH CS
   Epimerase  2 lVtGatGfiGsalvkallekgye.vigldrlssasntarledl.........elveldltdrsalerlf 60
                +VtG++  iG a++++l++kg   +++ +++ss+ +t++l+           + v++dltd++a  +++
  EEA20592.1 11 IVTGGSRGIGEAIARNLAKKGCSlLLNYTSESSRTKTEELASSftesfgvhcTTVRADLTDAQAASEII 79
                69*******************99899*****999999999998*******************9766655 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.1   0.0   7.5e-06     0.022       2      72 ..      12      80 ..      11      86 .. 0.85
   2 ?    1.7   0.0     0.045   1.4e+02     147     170 ..     164     187 ..     154     198 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 7.5e-06
                   EETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHH CS
  GDP_Man_Dehyd  2 iTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkgDltDssslerlla 72
                   +TG++  iG  +a+ L +kg     + +++s+ + ++ e+la++  e+   + + +++DltD+++  +++ 
     EEA20592.1 12 VTGGSRGIGEAIARNLAKKGCSL--LLNYTSESSRTKTEELASSFTESFGVHCTTVRADLTDAQAASEIII 80
                   9****9*************9987..56777777777778888777778888*************9999985 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.045
                    ----SHHHHHHHHHHHHHHHHHHH CS
  GDP_Man_Dehyd 147 fyPrsPYaaaKlyadwivvnyrea 170
                    f+ +s Y+ +K++ + +++ + ++
     EEA20592.1 164 FEGQSVYGGTKAALEAMTRTWARE 187
                    7889***************99775 PP

>> Gag_p17  gag gene protein p17 (matrix protein)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   4.1e-05      0.12      52     108 ..      28      84 ..      22     111 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 4.1e-05
     Gag_p17  52 teeGckkileqlepalktGseglrslyntvavllcvhqeikvkdtkealekvkreqn 108
                 +++Gc  +l+  + + +t +e+l s +     ++c   + ++ d++ a e++ +  +
  EEA20592.1  28 AKKGCSLLLNYTSESSRTKTEELASSFTESFGVHCTTVRADLTDAQAASEIIIDASK 84 
                 589*********************************************999876554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (293 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       367  (0.0204696); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.50
# Mc/sec: 1773.85
//
Query:       EEA20593.1  [L=127]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0017   18.4   0.3     0.0017   18.4   0.3    1.8  2  WLM       WLM domain
  ------ inclusion threshold ------
        1.4    9.4  12.3        2.7    8.5  11.7    1.8  1  SVIP      Small VCP/p97-interacting protein


Domain annotation for each model (and alignments):
>> WLM  WLM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.3   1.9e-07    0.0017     124     190 ..      14      77 ..       3      78 .. 0.86
   2 ?   -0.5   0.4      0.12   1.1e+03     154     175 ..      94     110 ..      79     125 .. 0.37

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 1.9e-07
         WLM 124 egflkeGkrlggkevrnksaeeeeekealekagiagkgarlGgrseektrskasareliaaAaerRl 190
                 + f ++G++lg+++ + +  ++ +++ + ++  ++g g++lGg s+  ++  a+ar  +a+Aa++R+
  EEA20593.1  14 DAFSQPGRVLGSSAASGT-PNQPARASVPGNVVSKGPGRTLGGASA--SQDTADARSKAAEAAQKRA 77 
                 7899*********99976.5777888889999999**********9..6999**************7 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.12
         WLM 154 kagiagkgarlGgrseektrsk 175
                  ++ ++++++l + s+      
  EEA20593.1  94 AQKARTQSQTLNAASQ-----A 110
                 2222222222222222.....2 PP

>> SVIP  Small VCP/p97-interacting protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5  11.7    0.0003       2.7      18      67 ..      59     110 ..      53     122 .. 0.74

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.0003
        SVIP  18 tpdaeerRrqqaEAAekRqe..eqesRGiknpesvkrkqkraeeaekreeea 67 
                   d + +R ++aEAA+kR e  +++s+G    + +++k++ ++++  ++++a
  EEA20593.1  59 SQDTADARSKAAEAAQKRAEalNASSKGKLGSQLAAQKARTQSQTLNAASQA 110
                 4688999***********9844688999988888888877776654444433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (127 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1515  (0.0845); expected 358.6 (0.02)
Passed bias filter:                      463  (0.0258241); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.30s 00:00:00.80 Elapsed: 00:00:00.48
# Mc/sec: 787.65
//
Query:       EEA20594.1  [L=494]
Description: C2H2 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    8.3e-16   57.5  56.2    7.9e-06   26.1   1.7    7.5  6  zf-C2H2      Zinc finger, C2H2 type
    5.7e-13   48.7  14.1    1.5e-08   34.6   1.4    7.0  6  zf-H2C2_2    Zinc-finger double domain
    3.2e-12   46.2  48.3    0.00025   21.6   1.4    7.6  6  zf-C2H2_4    C2H2-type zinc finger
    4.4e-08   33.2  11.9      0.005   17.1   0.1    5.1  4  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
    2.5e-06   27.3  20.8      0.002   18.1   0.4    5.1  4  zf-C2H2_6    C2H2-type zinc finger
    3.3e-05   24.1  17.2     0.0084   16.5   0.1    5.2  5  zf-met       Zinc-finger of C2H2 type
    8.6e-05   22.2  10.9        1.7    8.5   0.1    4.8  4  zf-C2H2_11   zinc-finger C2H2-type
    0.00031   21.3   0.2    0.00031   21.3   0.2    6.4  6  FOXP-CC      FOXP coiled-coil domain
     0.0046   16.7  33.9      0.025   14.3   0.5    6.6  6  zf-H2C2_5    C2H2-type zinc-finger domain
  ------ inclusion threshold ------
      0.019   15.0   4.1       0.86    9.7   0.4    3.1  2  XPA_N        XPA protein N-terminal
       0.43   11.2   9.6       0.53   10.9   0.1    3.6  3  Cript        Microtubule-associated protein CRIPT


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.7   1.7    0.0016       2.6       5      23 .]     297     316 ..     287     316 .. 0.82
   2 ?    4.3   5.3      0.04        65       1      23 []     329     355 ..     328     355 .. 0.88
   3 !   23.7   0.1   2.6e-08   4.3e-05       1      23 []     361     383 ..     361     383 .. 0.97
   4 !   26.1   1.7   4.8e-09   7.9e-06       1      23 []     389     411 ..     389     411 .. 0.99
   5 !    8.8   0.8    0.0015       2.4       1      23 []     417     441 ..     417     441 .. 0.97
   6 !   20.7   1.8   2.4e-07   0.00038       1      23 []     446     471 ..     446     471 .. 0.96

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0016
                 TTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   5 dCgksFkrksnLkrHirt.H 23 
                  C+ +F++  +L+ H+ t H
  EEA20594.1 297 MCNATFTSCGDLQEHLVTqH 316
                 8***************9988 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.04
                 EEET.TTT...EEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCp.dCg...ksFkrksnLkrHirtH 23 
                 y C  +C+   ++F++ks L+ H  tH
  EEA20594.1 329 YCCWyGCHrphEPFSQKSKLQGHFLTH 355
                 44559******************9999 PP

  == domain 3  score: 23.7 bits;  conditional E-value: 2.6e-08
                 EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirtH 23 
                 + C++Cgk F r+  L+rH r+H
  EEA20594.1 361 FACSVCGKAFARQATLERHERSH 383
                 78********************9 PP

  == domain 4  score: 26.1 bits;  conditional E-value: 4.8e-09
                 EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirtH 23 
                 +kC+ Cgk F+++s+Lk+H rtH
  EEA20594.1 389 FKCKQCGKAFTDSSELKTHSRTH 411
                 8*********************9 PP

  == domain 5  score: 8.8 bits;  conditional E-value: 0.0015
                 EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirtH 23 
                 +kC+  +C+    ++sn+ +H  tH
  EEA20594.1 417 FKCTfpGCDFQTGDSSNMSSHKLTH 441
                 89*********************99 PP

  == domain 6  score: 20.7 bits;  conditional E-value: 2.4e-07
                 EEET..TTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirt.H 23 
                 +kC+  +C k F+r+++LkrH++t H
  EEA20594.1 446 HKCTypGCAKAFTRPDQLKRHLKTtH 471
                 799999******************99 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   1.6       1.4   2.3e+03       2      21 ..     308     336 ..     307     337 .. 0.58
   2 !   15.7   0.4   8.9e-06     0.015       2      25 ..     348     371 ..     347     372 .. 0.92
   3 !   34.6   1.4   9.5e-12   1.5e-08       2      25 ..     376     399 ..     375     400 .. 0.96
   4 !   22.1   0.6   8.7e-08   0.00014       2      19 ..     404     421 ..     403     429 .. 0.84
   5 !    6.7   2.4    0.0065        11       1      26 []     433     459 ..     433     459 .. 0.84
   6 ?    3.4   0.3      0.07   1.1e+02       2      12 ..     463     474 ..     462     476 .. 0.82

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 1.4
   zf-H2C2_2   2 LrrHirk.Ht.......gekpyeCpl.Cd 21 
                 L+ H+ + H        g   y+C++ C+
  EEA20594.1 308 LQEHLVTqHIhpidgvqGHGYYCCWYgCH 336
                 6666544222446665555679**97676 PP

  == domain 2  score: 15.7 bits;  conditional E-value: 8.9e-06
   zf-H2C2_2   2 LrrHirkHtgekpyeCplCdkaFk 25 
                 L+ H+ +H + k + C++C+kaF+
  EEA20594.1 348 LQGHFLTHSNYKNFACSVCGKAFA 371
                 677********************8 PP

  == domain 3  score: 34.6 bits;  conditional E-value: 9.5e-12
   zf-H2C2_2   2 LrrHirkHtgekpyeCplCdkaFk 25 
                 L+rH r+H+gekp++C+ C+kaF+
  EEA20594.1 376 LERHERSHRGEKPFKCKQCGKAFT 399
                 89*********************7 PP

  == domain 4  score: 22.1 bits;  conditional E-value: 8.7e-08
   zf-H2C2_2   2 LrrHirkHtgekpyeCpl 19 
                 L+ H r+Htgekp++C +
  EEA20594.1 404 LKTHSRTHTGEKPFKCTF 421
                 899*************94 PP

  == domain 5  score: 6.7 bits;  conditional E-value: 0.0065
   zf-H2C2_2   1 nLrrHirkHtgekpyeCp..lCdkaFkt 26 
                 n + H  +H g  +++C    C+kaF++
  EEA20594.1 433 NMSSHKLTHSGR-RHKCTypGCAKAFTR 459
                 6789*******6.59999767*****85 PP

  == domain 6  score: 3.4 bits;  conditional E-value: 0.07
   zf-H2C2_2   2 LrrHirk.Htge 12 
                 L+rH+++ H+++
  EEA20594.1 463 LKRHLKTtHKVD 474
                 99****669986 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   0.1   0.00012      0.19       5      24 .]     297     316 ..     295     316 .. 0.95
   2 ?    3.7   4.6      0.09   1.5e+02       1      23 [.     328     355 ..     328     356 .. 0.84
   3 !   18.5   0.3   1.5e-06    0.0025       1      23 [.     361     383 ..     361     384 .. 0.96
   4 !   21.6   1.4   1.6e-07   0.00025       1      23 [.     389     411 ..     389     412 .. 0.97
   5 ?    4.6   0.4     0.045        73       1      23 [.     417     441 ..     417     442 .. 0.87
   6 !   15.3   1.2   1.7e-05     0.028       1      24 []     446     471 ..     446     471 .. 0.95

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 0.00012
   zf-C2H2_4   5 iCgksFsskkaLlrHlkthH 24 
                  C+++F+s+ +L+ Hl t+H
  EEA20594.1 297 MCNATFTSCGDLQEHLVTQH 316
                 7****************999 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.09
   zf-C2H2_4   1 fkCpi..C...gksFsskkaLlrHlkth 23 
                 ++C++  C   +++Fs k++L+ H++th
  EEA20594.1 328 YYCCWygChrpHEPFSQKSKLQGHFLTH 355
                 5677777888889**99999*******9 PP

  == domain 3  score: 18.5 bits;  conditional E-value: 1.5e-06
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlkth 23 
                 f C++Cgk F ++ +L rH ++h
  EEA20594.1 361 FACSVCGKAFARQATLERHERSH 383
                 89********************9 PP

  == domain 4  score: 21.6 bits;  conditional E-value: 1.6e-07
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlkth 23 
                 fkC++Cgk F+++++L++H +th
  EEA20594.1 389 FKCKQCGKAFTDSSELKTHSRTH 411
                 8*********************9 PP

  == domain 5  score: 4.6 bits;  conditional E-value: 0.045
   zf-C2H2_4   1 fkCpi..CgksFsskka..LlrHlkth 23 
                 fkC++  C   F + ++  +++H +th
  EEA20594.1 417 FKCTFpgC--DFQTGDSsnMSSHKLTH 441
                 8999999*..888777788*******9 PP

  == domain 6  score: 15.3 bits;  conditional E-value: 1.7e-05
   zf-C2H2_4   1 fkCpi..CgksFsskkaLlrHlkthH 24 
                 +kC++  C k F+++++L+rHlkt H
  EEA20594.1 446 HKCTYpgCAKAFTRPDQLKRHLKTTH 471
                 69*********************988 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.3      0.23   3.7e+02       7      23 ..     298     314 ..     296     318 .. 0.84
   2 !   17.1   0.1     3e-06     0.005       2      24 ..     361     383 ..     360     384 .. 0.94
   3 !   11.4   0.4   0.00019      0.31       2      20 ..     389     407 ..     388     411 .. 0.91
   4 !    7.5   0.1    0.0032       5.2       7      23 ..     453     469 ..     453     472 .. 0.92

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.23
                  TTBBBSSHHHHHCCTTS CS
  zf-C2H2_jaz   7 CdKyFksenaldnHlkS 23 
                  C+ +F s  +l++Hl +
   EEA20594.1 298 CNATFTSCGDLQEHLVT 314
                  **************966 PP

  == domain 2  score: 17.1 bits;  conditional E-value: 3e-06
                  CBBTTTTBBBSSHHHHHCCTTSH CS
  zf-C2H2_jaz   2 fYCvlCdKyFksenaldnHlkSK 24 
                  f C +C K F  + +l+ H++S+
   EEA20594.1 361 FACSVCGKAFARQATLERHERSH 383
                  78********************8 PP

  == domain 3  score: 11.4 bits;  conditional E-value: 0.00019
                  CBBTTTTBBBSSHHHHHCC CS
  zf-C2H2_jaz   2 fYCvlCdKyFksenaldnH 20 
                  f C+ C K F +++ l++H
   EEA20594.1 389 FKCKQCGKAFTDSSELKTH 407
                  99***************** PP

  == domain 4  score: 7.5 bits;  conditional E-value: 0.0032
                  TTBBBSSHHHHHCCTTS CS
  zf-C2H2_jaz   7 CdKyFksenaldnHlkS 23 
                  C+K F    +l+ Hlk+
   EEA20594.1 453 CAKAFTRPDQLKRHLKT 469
                  ****************8 PP

>> zf-C2H2_6  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.8   0.1    0.0089        14       6      24 ..     297     316 ..     296     317 .. 0.91
   2 !   18.1   0.4   1.2e-06     0.002       2      26 ..     361     385 ..     361     386 .. 0.95
   3 !   12.7   2.1   5.8e-05     0.094       2      24 ..     389     411 ..     389     414 .. 0.95
   4 ?    0.9   1.2       0.3   4.9e+02       2      24 ..     446     471 ..     445     472 .. 0.84

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0089
   zf-C2H2_6   6 vCsksFpslqaLggHk.ksH 24 
                  C+++F s  +L +H+  +H
  EEA20594.1 297 MCNATFTSCGDLQEHLvTQH 316
                 5**************98888 PP

  == domain 2  score: 18.1 bits;  conditional E-value: 1.2e-06
   zf-C2H2_6   2 heCsvCsksFpslqaLggHkksHrk 26 
                 + CsvC+k F  +  L+ H +sHr 
  EEA20594.1 361 FACSVCGKAFARQATLERHERSHRG 385
                 78*********************96 PP

  == domain 3  score: 12.7 bits;  conditional E-value: 5.8e-05
   zf-C2H2_6   2 heCsvCsksFpslqaLggHkksH 24 
                 ++C++C+k F    +L +H ++H
  EEA20594.1 389 FKCKQCGKAFTDSSELKTHSRTH 411
                 89********************9 PP

  == domain 4  score: 0.9 bits;  conditional E-value: 0.3
   zf-C2H2_6   2 heCsv..CsksFpslqaLggHkks.H 24 
                 h+C++  C k F   + L  H+k+ H
  EEA20594.1 446 HKCTYpgCAKAFTRPDQLKRHLKTtH 471
                 88888889999999999999998868 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.3   0.2     0.004       6.5       5      20 ..     297     312 ..     296     314 .. 0.92
   2 !   16.5   0.1   5.1e-06    0.0084       1      24 [.     361     384 ..     361     384 .. 0.94
   3 ?    4.5   1.9     0.029        48       1      25 []     389     411 ..     389     411 .. 0.92
   4 ?   -3.0   0.2       6.8   1.1e+04       6      19 ..     424     437 ..     424     438 .. 0.81
   5 ?    3.9   0.0     0.045        74       6      21 ..     453     468 ..     453     469 .. 0.90

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.004
      zf-met   5 lCnvtfnsesqlksHl 20 
                 +Cn tf+s ++l+ Hl
  EEA20594.1 297 MCNATFTSCGDLQEHL 312
                 7**************8 PP

  == domain 2  score: 16.5 bits;  conditional E-value: 5.1e-06
      zf-met   1 fyCelCnvtfnsesqlksHlqGKk 24 
                 f C++C + f  +++l+ H ++++
  EEA20594.1 361 FACSVCGKAFARQATLERHERSHR 384
                 56********************96 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.029
      zf-met   1 fyCelCnvtfnsesqlksHlqGKkH 25 
                 f C+ C + f++ s lk+H  +++H
  EEA20594.1 389 FKCKQCGKAFTDSSELKTH--SRTH 411
                 78999**************..8888 PP

  == domain 4  score: -3.0 bits;  conditional E-value: 6.8
      zf-met   6 CnvtfnsesqlksH 19 
                 C+ ++ + s++ sH
  EEA20594.1 424 CDFQTGDSSNMSSH 437
                 77777788999999 PP

  == domain 5  score: 3.9 bits;  conditional E-value: 0.045
      zf-met   6 CnvtfnsesqlksHlq 21 
                 C + f+ + qlk Hl+
  EEA20594.1 453 CAKAFTRPDQLKRHLK 468
                 7788**********97 PP

>> zf-C2H2_11  zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.1      0.06        98      10      26 ..     298     314 ..     296     316 .. 0.86
   2 !    8.5   0.1     0.001       1.7       7      23 ..     363     379 ..     359     381 .. 0.93
   3 !    8.0   0.1    0.0014       2.3       5      23 ..     389     407 ..     386     410 .. 0.88
   4 !    6.6   0.4     0.004       6.5      10      29 .]     453     472 ..     446     472 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.06
  zf-C2H2_11  10 CGlcftSqlsLsRHlfI 26 
                 C   ftS + L+ Hl  
  EEA20594.1 298 CNATFTSCGDLQEHLVT 314
                 9999**********975 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.001
  zf-C2H2_11   7 CleCGlcftSqlsLsRH 23 
                 C  CG  f+ q  L RH
  EEA20594.1 363 CSVCGKAFARQATLERH 379
                 999************** PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.0014
  zf-C2H2_11   5 cqCleCGlcftSqlsLsRH 23 
                 ++C +CG  ft +  L+ H
  EEA20594.1 389 FKCKQCGKAFTDSSELKTH 407
                 69*********99999988 PP

  == domain 4  score: 6.6 bits;  conditional E-value: 0.004
  zf-C2H2_11  10 CGlcftSqlsLsRHlfIvHK 29 
                 C   ft    L+RHl  +HK
  EEA20594.1 453 CAKAFTRPDQLKRHLKTTHK 472
                 6777888889*********9 PP

>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   1.3       0.3   4.9e+02       6      44 ..      26      67 ..      23      70 .. 0.79
   2 !    6.4   1.1    0.0084        14       5      31 ..     287     317 ..     285     322 .. 0.83
   3 ?    1.3   1.2      0.35   5.7e+02       6      25 ..     329     351 ..     325     383 .. 0.70
   4 ?   -0.7   0.1       1.5   2.4e+03      11      28 ..     393     410 ..     390     418 .. 0.85
   5 ?    3.8   0.1     0.055        89       6      26 ..     418     438 ..     415     447 .. 0.85
   6 !   21.3   0.2   1.9e-07   0.00031       5      37 ..     446     478 ..     444     483 .. 0.91

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.3
     FOXP-CC  6 vCkWPgC.ekvledve..eflkhlnseHalddkstaqlrvqm 44
                vC   +C e+++e+ +   f kh+ ++ +  d sta l  q 
  EEA20594.1 26 VCSAANCeEEHCESTGpaCFDKHCFEDGQNVDVSTANLLQQT 67
                67777995567887652269****************998776 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.0084
     FOXP-CC   5 gvCkWPg....CekvledveeflkhlnseHa 31 
                  vC+W      C++ +++ +++++hl ++H 
  EEA20594.1 287 HVCRWNHgismCNATFTSCGDLQEHLVTQHI 317
                 689996444449*****************96 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.35
     FOXP-CC   6 vCkWPgC...ekvledveeflkh 25 
                  C W gC   ++ +++ ++++ h
  EEA20594.1 329 YCCWYGChrpHEPFSQKSKLQGH 351
                 6******4433334444444444 PP

  == domain 4  score: -0.7 bits;  conditional E-value: 1.5
     FOXP-CC  11 gCekvledveeflkhlns 28 
                  C k+++d++e+  h ++
  EEA20594.1 393 QCGKAFTDSSELKTHSRT 410
                 599*********999765 PP

  == domain 5  score: 3.8 bits;  conditional E-value: 0.055
     FOXP-CC   6 vCkWPgCekvledveeflkhl 26 
                  C  PgC+  + d++++ +h 
  EEA20594.1 418 KCTFPGCDFQTGDSSNMSSHK 438
                 5**********9999999984 PP

  == domain 6  score: 21.3 bits;  conditional E-value: 1.9e-07
     FOXP-CC   5 gvCkWPgCekvledveeflkhlnseHalddkst 37 
                   C  PgC k+++  +++ +hl+++H++d+++ 
  EEA20594.1 446 HKCTYPGCAKAFTRPDQLKRHLKTTHKVDNNTQ 478
                 57**************************99875 PP

>> zf-H2C2_5  C2H2-type zinc-finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.0         1   1.6e+03      15      24 ..     307     316 ..     305     316 .. 0.89
   2 ?    1.1   0.1      0.21   3.4e+02      11      25 ..     343     356 ..     343     357 .. 0.90
   3 ?    0.9   0.1      0.24   3.8e+02      13      26 .]     373     385 ..     371     385 .. 0.80
   4 ?    3.8   7.3      0.03        49       1      26 []     389     413 ..     389     413 .. 0.96
   5 !   14.3   0.5   1.5e-05     0.025       1      26 []     417     443 ..     417     443 .. 0.94
   6 !   10.5   1.5   0.00024      0.39      12      25 ..     459     472 ..     458     472 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 1
   zf-H2C2_5  15 nLkRHlrrkH 24 
                 +L++Hl ++H
  EEA20594.1 307 DLQEHLVTQH 316
                 79****9999 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.21
   zf-H2C2_5  11 awksnLkRHlrrkHt 25 
                 ++ks L+ H + +H+
  EEA20594.1 343 SQKSKLQGHFL-THS 356
                 68*********.**8 PP

  == domain 3  score: 0.9 bits;  conditional E-value: 0.24
   zf-H2C2_5  13 ksnLkRHlrrkHtg 26 
                  ++L+RH r  H g
  EEA20594.1 373 QATLERHER-SHRG 385
                 589****88.8876 PP

  == domain 4  score: 3.8 bits;  conditional E-value: 0.03
   zf-H2C2_5   1 YKCsqCDYstawksnLkRHlrrkHtg 26 
                 +KC qC    + +s+Lk H r +Htg
  EEA20594.1 389 FKCKQCGKAFTDSSELKTHSR-THTG 413
                 89****9999***********.***8 PP

  == domain 5  score: 14.3 bits;  conditional E-value: 1.5e-05
   zf-H2C2_5   1 YKCsq..CDYstawksnLkRHlrrkHtg 26 
                 +KC++  CD+ t  +sn+  H + +H+g
  EEA20594.1 417 FKCTFpgCDFQTGDSSNMSSHKL-THSG 443
                 7898888****************.**98 PP

  == domain 6  score: 10.5 bits;  conditional E-value: 0.00024
   zf-H2C2_5  12 wksnLkRHlrrkHt 25 
                 ++++LkRHl+++H+
  EEA20594.1 459 RPDQLKRHLKTTHK 472
                 6899*********7 PP

>> XPA_N  XPA protein N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.2     0.016        26      17      25 ..     358     366 ..     356     368 .. 0.89
   2 ?    9.7   0.4   0.00053      0.86       3      14 ..     390     401 ..     388     406 .. 0.93

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.016
       XPA_N  17 ldnFdysVC 25 
                 ++nF +sVC
  EEA20594.1 358 YKNFACSVC 366
                 68******* PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.00053
       XPA_N   3 kCdeCgkefldS 14 
                 kC++Cgk+f dS
  EEA20594.1 390 KCKQCGKAFTDS 401
                 7**********9 PP

>> Cript  Microtubule-associated protein CRIPT
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   1.0       1.1   1.8e+03      25      64 ..      89     129 ..      80     140 .. 0.65
   2 ?   10.9   0.1   0.00033      0.53      58      81 ..     349     372 ..     334     380 .. 0.80
   3 ?    3.8   0.2     0.052        85      71      87 ..     390     406 ..     387     408 .. 0.85

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 1.1
       Cript  25 igenkllskk..krfnpyaaysskCkiCktkveqkgakYCqk 64 
                 ++e+++l+++  ++ + y+++s++  +C ++ +  +   Cq+
  EEA20594.1  89 VAESHTLNQAtsRHQHCYTNNSFSDFQCHSTGHG-SLAACQQ 129
                 6777888555322557888888887788777665.4444544 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00033
       Cript  58 gakYCqkCaYkkgiCamCGkklld 81 
                 + ++ ++  Yk+ +C++CGk+ + 
  EEA20594.1 349 QGHFLTHSNYKNFACSVCGKAFAR 372
                 4589999*************9854 PP

  == domain 3  score: 3.8 bits;  conditional E-value: 0.052
       Cript  71 iCamCGkklldtksskq 87 
                  C+ CGk+ +d ++ k+
  EEA20594.1 390 KCKQCGKAFTDSSELKT 406
                 5********99998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (494 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       925  (0.0515924); expected 358.6 (0.02)
Passed bias filter:                      355  (0.0198003); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.58u 0.32s 00:00:00.89 Elapsed: 00:00:00.48
# Mc/sec: 3104.11
//
Query:       EEA20595.1  [L=1207]
Description: DEAD/DEAH box RNA helicase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.3e-49  167.5   0.0      7e-49  166.0   0.0    1.8  2  DEAD        DEAD/DEAH box helicase
    2.1e-27   95.7   0.0    1.2e-26   93.2   0.0    2.3  2  Helicase_C  Helicase conserved C-terminal domain
     0.0026   17.8   0.0      0.008   16.2   0.0    1.9  2  ResIII      Type III restriction enzyme, res subunit


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  166.0   0.0   1.2e-52     7e-49       1     175 [.     599     772 ..     599     773 .. 0.94
   2 ?   -2.7   0.0      0.71   4.3e+03      36     104 ..     816     884 ..     811     900 .. 0.64

  Alignments for each domain:
  == domain 1  score: 166.0 bits;  conditional E-value: 1.2e-52
                 -HHHHHHHHHHHTTCEEEEEESTTSSHHHHHHHHHHHHHHHS...TTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   1 tdiQaeaiplilgggdvlvaaeTGsGKTlaflipvlqivyet...kgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldn 96 
                 t+iQ++a+p+i++g+dv++ a+TGsGKT  fl+p+++++ ++   ++ +gp  li++PtreLa q+++++k f+k ++lr+++ +gg + +dq+++l++
  EEA20595.1 599 TSIQSQALPAIMSGRDVIGVAKTGSGKTVSFLLPMFRHIKDQrplENMEGPISLIMTPTRELATQIHKDCKPFLKALNLRAVCAYGGAPIKDQIAELKR 697
                 78*************************************8889999***************************************************99 PP

                 TCSEEEEEHHHHHHHH..HCTS.SHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHHHH CS
                 xxxxxxxxxxxxxxxx..xxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  97 gvdivvgtpgrlddll..stgk.lnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlpkdvkk 175
                 g++ivv tpgr++dll  + g+  nl++v+++VlDEadr+ d+gf++++ +i+++++      + ++q++++SAT+p++++ 
  EEA20595.1 698 GAEIVVCTPGRMIDLLaaNAGRvTNLRRVTYVVLDEADRMFDMGFEPQVMKIMTNIR------P-NKQTVLFSATFPRNMEA 772
                 9*************99885555367*******************************3......3.456*********99876 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 0.71
                 HHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHH...TT.CSEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xx.xxxxxxx RF
        DEAD  36 lqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskld...ng.vdivvgt 104
                 l ++y+++ ++  ++li +  +e a   l++l + + +    +++i gg+++ d  s+++   +g   ++++t
  EEA20595.1 816 LGNLYSDEANEDARTLIFVDRQEAADSLLRELMRKGYP----CMSIHGGKDQIDRDSTIEdfkAGiFPVLIAT 884
                 55667767778888999999999999888888777664....5678888888777777732213355555555 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0      0.52   3.1e+03      18      62 ..     650     698 ..     637     736 .. 0.75
   2 !   93.2   0.0     2e-30   1.2e-26       2     111 .]     808     922 ..     807     922 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.52
                 EEEEEESSHH...HHHH.HHHHHHHTTSTEEEESTTSTHHHHHHHHHHH CS
  Helicase_C  18 kilifvntid...rlek.vklllekkgikvavlhgelpqnereeileqf 62 
                  +li+++t++   +++k +k +l+  ++++++ +g  p +++++ l++ 
  EEA20595.1 650 ISLIMTPTRElatQIHKdCKPFLKALNLRAVCAYGGAPIKDQIAELKRG 698
                 5688899999655444477777777799999999999999988777765 PP

  == domain 2  score: 93.2 bits;  conditional E-value: 2e-30
                 HHHHHHHHH.....HHTTTTSEEEEEESSHHHHHH..HHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSS CS
  Helicase_C   2 kleallell.....kleeeggkilifvntidrlek..vklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdl 93 
                 k+++llell     ++ +e+ ++lifv +++ +++   +l+  +kg+ +  +hg   q +r+ ++e+f++g + vLiat+va+rG+d+++++lV+n+d+
  EEA20595.1 808 KFLRLLELLgnlysDEANEDARTLIFVDRQEAADSllRELM--RKGYPCMSIHGGKDQIDRDSTIEDFKAGIFPVLIATSVAARGLDVKQLKLVVNYDA 904
                 566777777777899999*************9994433333..67****************************************************** PP

                 SSSHHHHHHHHTTSSSTT CS
  Helicase_C  94 prnvtsyiqriGRtgRag 111
                 p  +++y++r+GRtgRag
  EEA20595.1 905 PNHLEDYVHRAGRTGRAG 922
                 ****************97 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   1.3e-06     0.008      28     170 ..     616     767 ..     597     768 .. 0.74
   2 ?   -4.0   0.0       2.2   1.3e+04      53      75 ..     826     848 ..     816     868 .. 0.70

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.3e-06
                 EEEESTTSTHHHHH.HHHHHHH-S..........-EEEEESSHHHHHHHHHHGGGGTGG.....GEEEESSS-B--.......-SEEEEEHHHHHHTH. CS
      ResIII  28 likmaTGtGKTlva.aklierllkkgkee.....kflflvprkslleqtleefkkflseayke.igkkvsgdkkkakekdstnkkilvttiqsldadse 119
                 + ++ TG+GKT+   + + ++++ +++ e       l++ p+++l  q  ++ k fl+  + + ++       k++ ++ +  ++i+v t  ++   + 
  EEA20595.1 616 IGVAKTGSGKTVSFlLPMFRHIKDQRPLEnmegpISLIMTPTRELATQIHKDCKPFLKALNLRaVCAYGGAPIKDQIAELKRGAEIVVCTPGRMIDLL- 713
                 55789*******995555566666666669999999**********************99888744443333333345568889******99998888. PP

                 .......HHHTTT-SEEEEETGGGTTS....TTTHHHHHT---.SEEEEEESS-S CS
      ResIII 120 eeeeeseellrdrfdviiiDEaHrlgak...kswreilekfke.avllglTATpe 170
                  + ++       r  +++ DEa r+ ++    ++ +i+ ++++ +  + ++AT++
  EEA20595.1 714 -AANAGRVTNLRRVTYVVLDEADRMFDMgfePQVMKIMTNIRPnKQTVLFSATFP 767
                 .23334444444555************96655888888888653677999***97 PP

  == domain 2  score: -4.0 bits;  conditional E-value: 2.2
                 ...-EEEEESSHHHHHHHHHHGG CS
      ResIII  53 keekflflvprkslleqtleefk 75 
                 +  ++l++v+r++  + +l+e++
  EEA20595.1 826 EDARTLIFVDRQEAADSLLRELM 848
                 33389999999887777776654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1207 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1322  (0.0737353); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 1.26u 0.39s 00:00:01.65 Elapsed: 00:00:00.59
# Mc/sec: 6163.05
//
Query:       EEA20596.1  [L=504]
Description: alpha-L-arabinofuranosidase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.6e-28   98.4   0.0    6.7e-28   97.9   0.0    1.2  1  Alpha-L-AF_C  Alpha-L-arabinofuranosidase C-terminal domain


Domain annotation for each model (and alignments):
>> Alpha-L-AF_C  Alpha-L-arabinofuranosidase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.9   0.0   3.8e-32   6.7e-28       1     168 []     308     496 ..     308     496 .. 0.88

  Alignments for each domain:
  == domain 1  score: 97.9 bits;  conditional E-value: 3.8e-32
                   EEEEE--S-..S..SS------HHHHHHHHHHHHHHHHHTTT--EEEES-SBSTT-.....SEEEETTE.EEE-HHHHHHHHHHHS--SEEEEEEEE CS
                   xxxxxxxxx..x..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Alpha-L-AF_C   1 gEyavwyds..p..glleqqntledAlaeAafltglernaDvVkmasyAplvnviaatqWspdliwdngkvvgtpsYyvqklfsknaggtvlpvele 93 
                   +E++vw     +   ++e+ +tl+dAla+++fl+++ r++    ma++A+ vnvi+     p++++++g ++++++++++ lfsk+++g +++ +++
    EEA20596.1 308 DEWNVWDPLraEgrFGAEETYTLSDALAVGVFLNVFIRKSRDLGMACIAQSVNVIS-----PLMTSPTG-ITKQTTWWPLLLFSKYMRGWTIAAHVA 398
                   9*****43354265789999************************************.....********.*************************** PP

                   --EEEEEEEET.............................SS--EEEEEEETT-.-SEEEEEEEEE-.STT----SSSTTSSEEEEEEE.EE-E..E CS
                   xxxxxxxxxxx.............................xxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Alpha-L-AF_C  94 spkyeikgege.............................aeeavevevdleglekaskaevtvlsg.dlkaeNtfenpekvvpkeeklakvsggkf 160
                   +++y+ ++                                 +e +++ev++eg+     ++v +++g d++ +N ++ +e+v +ke++    + g+ 
    EEA20596.1 399 CGSYNGDTSPAwlrsvkdtpwldvsavlsddgfvnvvtinVHEHKDFEVKVEGA--QGPVNVFTVTGaDVTVTN-MKGEEEVGIKETTW---D-GQE 488
                   ****44433337778888999*******************66689********8..788999***999******.666699***99988...4.455 PP

                   EEEE-TTE CS
                   xxxxxxxx RF
  Alpha-L-AF_C 161 tytlpayS 168
                   +y +p++S
    EEA20596.1 489 NYVFPKHS 496
                   9*****99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (504 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       446  (0.0248759); expected 358.6 (0.02)
Passed bias filter:                      408  (0.0227564); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.70u 0.34s 00:00:01.04 Elapsed: 00:00:00.58
# Mc/sec: 2628.83
//
Query:       EEA20597.1  [L=451]
Description: MFS sugar transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-90  304.8  15.9    1.3e-90  304.5  15.9    1.0  1  Sugar_tr  Sugar (and other) transporter
      1e-21   77.2  31.6    1.8e-15   56.7  11.9    2.0  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.051   13.6   1.9       0.13   12.3   1.9    1.7  1  MatC_N    Dicarboxylate carrier protein MatC N-terminus


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  304.5  15.9   2.1e-94   1.3e-90      52     452 .]       5     413 ..       2     413 .. 0.92

  Alignments for each domain:
  == domain 1  score: 304.5 bits;  conditional E-value: 2.1e-94
                 HHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHH CS
    Sugar_tr  52 vsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfG 150
                 +s++  Ga++G+ +ag+ gd++GR+++++i++++f+ g+ lq  a+   ++  l++gR+++G+++G+ +++vP y++E++++++Rg+++sl+q+++ +G
  EEA20597.1   5 LSMLTTGAFFGAALAGPTGDYLGRRWTIAIGSLIFCLGGGLQTGAQ---NISYLYTGRFFAGFAAGILTMIVPPYQAELCHPDIRGRVTSLQQFMLGVG 100
                 688999****************************************...9************************************************* PP

                 HHHHHHHHHHH.HTSS-..TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHHTT-HHHHHHHHHHHHHC.HHHHHHHHHHHHHHHHHHH......... CS
    Sugar_tr 151 ilvaaifglgl.nktsn..adgwrillglqlvpallllilllflPESPrylvekgkeeeakevlaklrge.edadrelaeekdsleaeqeee....kas 241
                  l a+++ +g+   +s   + +wr+ lg+q++pa++l  l++ +PESPr+l+ +g+e e  +vla+l    +++d  + +e++ ++++ + e     +s
  EEA20597.1 101 ALCASWISYGTyIGFSPsdSAQWRVSLGIQIIPAVILGSLIMIFPESPRWLIDNGREAEGLKVLARLHSHgDENDSWVRAEFSLIQESITFEheneAKS 199
                 ***********555555999**********************************************776666666666666666666655555555999 PP

                 HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH..HHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH... CS
    Sugar_tr 242 wkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsks..llvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilg..i 336
                 + el++s++ ++rl+++++lq+  q+tG+ ai yys +if+++g+s +  l   +i +v+  +  f  ++l+drfGRR  l++G    ++ f+i +   
  EEA20597.1 200 YVELFTSRSAFRRLFLCCALQASIQMTGVSAIQYYSVEIFNQIGISGDqtLRYQAINSVIALLGEFSCMMLIDRFGRRWPLIMGNQANMVTFIIACilL 298
                 999999999***************************************99899999999999999999****************666666666666322 PP

                 .HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHH CS
    Sugar_tr 337 valllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvff 435
                 + ++ +a++++a  ++i+++ l+ + f+++ gp+ w++ +E+f++++R+k+ +ia+++++ +n  i++++pi+++++  + + +vf +++   ++f ++
  EEA20597.1 299 ALYPPEANNSGAHWGFIIMTWLYNFSFSATCGPLSWIIPAEVFDTRTRAKGVSIATMTSFAFNTMIGQVTPIAMQNVR-YRYWVVFIICNFTNALFFWL 396
                 366666666*********************************************************************.******************** PP

                 HS--STT--CCCCGGGT CS
    Sugar_tr 436 fvpetkgrtleeieelf 452
                  +pet  ++lee++ lf
  EEA20597.1 397 LMPETSKLPLEEMNSLF 413
                 *************9987 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.7  11.9     3e-19   1.8e-15      39     189 ..       6     170 ..       3     225 .. 0.80
   2 !   25.7  12.8   8.4e-10     5e-06       3     179 ..     216     404 ..     213     425 .. 0.67

  Alignments for each domain:
  == domain 1  score: 56.7 bits;  conditional E-value: 3e-19
       MFS_1  39 tlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfasslwlllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGail 136
                 ++ + ga++++ ++G+ +d +Grr+++ +g l+f+lg +l    a+++ +l+ +r+++G++ag+l+ ++  + a++ +++ rgr+++l + + ++Ga++
  EEA20597.1   6 SMLTTGAFFGAALAGPTGDYLGRRWTIAIGSLIFCLGgGLQTG-AQNISYLYTGRFFAGFAAGILTMIVPPYQAELCHPDIRGRVTSLQQFMLGVGALC 103
                 556678999999*************************777777.59999************************************************** PP

       MFS_1 137 gpllggllasslg......Wravfyilaivsllafvlfllllpeepperkrkspkeee...........k 189
                 +  ++   +  ++      Wr++  i  i +++++    l +  ++++r+     +e            +
  EEA20597.1 104 ASWISYGTYIGFSpsdsaqWRVSLGIQIIPAVILGS---LIMIFPESPRWLIDNGREAeglkvlarlhsH 170
                 ******999777799*******************88...4444555555554444443346666666663 PP

  == domain 2  score: 25.7 bits;  conditional E-value: 8.4e-10
       MFS_1   3 laaflsalarsilgpalplalaedlg...ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll..fa.........sslwl 87 
                 ++a+ ++++++ ++++   +  e ++   is+++     ++ ++ a+++ +  + l+drfGrr+ l++g  +  +++++++  +a           +w 
  EEA20597.1 216 CCALQASIQMTGVSAIQY-YSVEIFNqigISGDQTLRYQAINSVIALLGEFSCMMLIDRFGRRWPLIMGNQANMVTFIIACilLAlyppeannsGAHWG 313
                 455555555555444443.44444443338888877799******************************877777733333332244455454433886 PP

       MFS_1  88 llvlrvlqGlga.galfpagaaliadwfpkeergraigllsa.gfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepper 179
                 ++++  l  +   ++  p++ ++ a++f  + r+++++++++ +f++ +++g +   + ++++  r+ ++++ i++ +   lf++ll+ e ++ 
  EEA20597.1 314 FIIMTWLYNFSFsATCGPLSWIIPAEVFDTRTRAKGVSIATMtSFAFNTMIGQVTP-IAMQNV--RYRYWVVFIICNFTNALFFWLLMPETSKL 404
                 7777777777665****************************955666668886655.555555..45577777777666444445554444443 PP

>> MatC_N  Dicarboxylate carrier protein MatC N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   1.9   2.2e-05      0.13      16     116 ..     273     372 ..     258     388 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 2.2e-05
      MatC_N  16 iiatvrkinmgllalaaafligtvllgldpkevlagfPadlfltlvavtylfaiarvnGtidlLvkvavravrgrvaaipwvlfllaalltalGalspa 114
                   + + ++ mg  a  ++f+i+ +ll l p e  +   a   +++++  y f+++ + G + +++ + v  +r+r + + +   +  a  t +G ++p 
  EEA20597.1 273 RFGRRWPLIMGNQANMVTFIIACILLALYPPEANNS-GAHWGFIIMTWLYNFSFSATCGPLSWIIPAEVFDTRTRAKGVSIATMTSFAFNTMIGQVTPI 370
                 4567778999*********************97654.667778888888999999********************999988877777778888888887 PP

      MatC_N 115 av 116
                 a+
  EEA20597.1 371 AM 372
                 77 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (451 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       538  (0.0300073); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.61u 0.30s 00:00:00.90 Elapsed: 00:00:00.51
# Mc/sec: 2683.62
//
Query:       EEA20598.1  [L=248]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.3e-33  115.5  10.7    3.1e-33  114.3  10.7    1.7  1  Nefa_Nip30_N  N-terminal domain of NEFA-interacting nuclear p
  ------ inclusion threshold ------
       0.26   11.5   8.6       0.12   12.6   5.0    2.2  2  Seryl_tRNA_N  Seryl-tRNA synthetase N-terminal domain


Domain annotation for each model (and alignments):
>> Nefa_Nip30_N  N-terminal domain of NEFA-interacting nuclear protein NIP30
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.3  10.7   3.4e-37   3.1e-33       1     104 [.       5     108 ..       5     109 .. 0.94

  Alignments for each domain:
  == domain 1  score: 114.3 bits;  conditional E-value: 3.4e-37
  Nefa_Nip30_N   1 Fvseseleeereerqeewekarkeleaerkkeeaeee.edgksLyerLqenkaaKqeefeeklklknqfraLdedEveFLdeveekkreeeerrkke 96 
                   Fv  +++ +e+++r++ew++a++ele+er+++++  + +dgksLye+Lq+nk+aKqe+fee+++lknqfr+LdedEveFLd++ e++r++e+++kke
    EEA20598.1   5 FVPGGTI-DEPTQRDDEWRRAQQELEDERRRKAELGKqNDGKSLYEVLQQNKMAKQEAFEESIRLKNQFRSLDEDEVEFLDSLLESTRAKEAAVKKE 100
                   8889999.889999**************9995545555*********************************************************** PP

  Nefa_Nip30_N  97 eeeeleeF 104
                   ++e+l+++
    EEA20598.1 101 TAEHLAAY 108
                   ******99 PP

>> Seryl_tRNA_N  Seryl-tRNA synthetase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   5.0   1.4e-05      0.12      27      97 ..      10      86 ..       4      92 .. 0.80
   2 ?   -1.0   0.1      0.22     2e+03      77      91 ..      99     113 ..      87     121 .. 0.39

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.4e-05
                  HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTT......S-TCCCCCCCHHHHHHHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N 27 dvdelleldekrrelqveleelqaerNelskeIgkakkkk......edaeeliaevkelkeelkaleaelkeleael 97
                  ++de  + d+++r++q+ele+ ++++ el+k+   ++  +        ++e  +e+  lk+++  l++++ e  + l
    EEA20598.1 10 TIDEPTQRDDEWRRAQQELEDERRRKAELGKQNDGKSLYEvlqqnkMAKQEAFEESIRLKNQFRSLDEDEVEFLDSL 86
                  789999***********************98865544333233225889999999999*****99999998877666 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.22
                   HHHHHHHHHHHHHHH CS
  Seryl_tRNA_N  77 kelkeelkaleaelk 91 
                   ke  e l+a++ + +
    EEA20598.1  99 KETAEHLAAYQRQRE 113
                   222222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (248 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1619  (0.0903006); expected 358.6 (0.02)
Passed bias filter:                      582  (0.0324614); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 1608.17
//
Query:       EEA20599.1  [L=298]
Description: glycerol dehydrogenase Gcy1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.6e-45  155.5   0.0      1e-43  149.7   0.0    2.0  1  Aldo_ket_red  Aldo/keto reductase family


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  149.7   0.0   5.6e-48     1e-43       2     292 ..      22     276 ..      21     278 .. 0.92

  Alignments for each domain:
  == domain 1  score: 149.7 bits;  conditional E-value: 5.6e-48
                   EEEE-SSS-ST.TS-HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH-TTTGGG-EEEEEE--SSSTTSSSS-HHHHHHHHHHHHHHHT CS
  Aldo_ket_red   2 lglGtwqlgskeeiskeealellrraleaGinffDtAevYgkgqseellGealkksrkkreeviiatKvdlrdaeiksglskeniresleeslkrLg 98 
                   +glGtwq       +++e+ e++++al aG++++DtA +Y    +e+++G+ +k+s+ +re++ i+tK+        ++  + +++  ++ sl+ Lg
    EEA20599.1  22 VGLGTWQS------KPNEVREAVKTALLAGYRHIDTALAY---GNEHEVGQGIKDSGIPREQIWITTKL--------DNAWHHRVQDGINSSLSSLG 101
                   79999955......589***********************...9*************************........7777889999********** PP

                   -S-EEEEEE-S--TTS-...........HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHH..HHTTT--EEEEE-B-BTT-HHHHTTHHHHHHHTT CS
  Aldo_ket_red  99 tdyvDllllHrpdpslp..........sieevldaleelvkeGkiraiGvSnfsveqleka..kkkkkvkivavqveynllreleeegllelckkkg 183
                   +dyvDl+l+H+p +++p          +  ++++ +++l   Gk+r+iGvSnf ++ le++    + k+ ++++q+e ++     + +l+e+   kg
    EEA20599.1 102 VDYVDLYLVHWPSSTDPnddmkhlpdwDFIKTWEEIQKLPATGKVRNIGVSNFGIKNLERLlnAPTTKIVPAVNQIELHPN--NPSPKLVEYNVSKG 196
                   *************************************************************55445555578888888888..************** PP

                   -EEEEBSTTGGGTTGTTTSS---SSSCCC-------TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTSTT-SEEEE--SSHHHHHHHHGGGG-- CS
  Aldo_ket_red 184 vpliaysplggGlltgkyqseedkedkeprkdlkrdertsknldaaeelselakehgvslaqlalryalsqpavgivipgasnieqlednldalelk 280
                   + +  ys+lg+                               l ++++l ++a+++g++++ql l++ +  +++ +vip++ + e++e n++  e++
    EEA20599.1 197 IHCTGYSCLGSTNSP---------------------------LYKDSTLLKMAEKKGKTPQQLLLAWGV--QKGWSVIPKSVSKERIEKNFQLDEWE 264
                   **********43222...........................356899*********************..9************************* PP

                   --HHHHHHHHHH CS
  Aldo_ket_red 281 lseeevaeldel 292
                   ls+ee++el +l
    EEA20599.1 265 LSAEELEELSSL 276
                   ********9887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (298 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       438  (0.0244297); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.48
# Mc/sec: 1860.78
//
Query:       EEA20600.1  [L=441]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (441 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       328  (0.0182944); expected 358.6 (0.02)
Passed bias filter:                      294  (0.016398); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.49
# Mc/sec: 2711.01
//
Query:       EEA20601.1  [L=268]
Description: casein kinase 2 beta' regulatory subunit Ckb2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    5.7e-79  264.2   0.2    7.2e-79  263.8   0.2    1.1  1  CK_II_beta   Casein kinase II regulatory subunit
  ------ inclusion threshold ------
      0.094   13.1   3.6       0.18   12.2   3.6    1.4  1  Uso1_p115_C  Uso1 / p115 like vesicle tethering protein, C te
       0.12   12.5   0.0       0.22   11.6   0.0    1.5  1  CxC5         CxC5 like cysteine cluster associated with KDZ t
        1.7    8.1   3.5        3.5    7.2   3.5    1.4  1  GCIP         Grap2 and cyclin-D-interacting


Domain annotation for each model (and alignments):
>> CK_II_beta  Casein kinase II regulatory subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  263.8   0.2   1.6e-82   7.2e-79       2     182 .]      16     195 ..      15     195 .. 0.98

  Alignments for each domain:
  == domain 1  score: 263.8 bits;  conditional E-value: 1.6e-82
  CK_II_beta   2 WiswflslkgneyfvevdedfiedkfnltgLseevpnykealelildveeeeeleeseksevessaelLYgliHaryiltkkglakmlekykkkefgrC 100
                 W +wf+s++gneyf+e+de++++d+fnltgL++ev++y+ al+li+dv + +  +++ ++++e+sa++LYgl+Haryi+t++glakml+kykk++fg+C
  EEA20601.1  16 WRDWFISSRGNEYFCEIDEEYLTDRFNLTGLNTEVQYYQYALDLITDVFDLD-ADDDLREQIEKSARHLYGLVHARYIVTTRGLAKMLDKYKKGDFGKC 113
                 99*********************************************87765.889999**************************************** PP

  CK_II_beta 101 prvlCekqkvLPvGlsdkpgektvklyCpkCedvYspkssrsrsidGafFGttfphlllltypelepkkskekyepriyGfk 182
                 prvlC+++++LP+G+sd p++ktvklyC kCed+Y+pkssr+ sidGa+FGt+f ++l+++yp l p+ks ++yepriyGfk
  EEA20601.1 114 PRVLCDQHPLLPMGQSDLPNQKTVKLYCAKCEDIYNPKSSRHASIDGAYFGTSFHNILFQVYPALVPEKSIQRYEPRIYGFK 195
                 *********************************************************************************8 PP

>> Uso1_p115_C  Uso1 / p115 like vesicle tethering protein, C terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   3.6     4e-05      0.18      92     125 ..     206     243 ..     205     246 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 4e-05
  Uso1_p115_C  92 leeKvekykarLkelGeev...sddedddeddeed.ee 125
                  +++++e+ k+rL +lG +    +d+ed+++d e+d ++
   EEA20601.1 206 QDARREEMKERLNKLGIDPgfiEDSEDENDDFEDDiDD 243
                  799***************98887777777776666443 PP

>> CxC5  CxC5 like cysteine cluster associated with KDZ transposases
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   4.9e-05      0.22      45      68 ..     135     159 ..     122     205 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 4.9e-05
        CxC5  45 wvlslyCpkCktrYypdyyvhdg.v 68 
                 +++ lyC kC+ +Y+p+ ++h +  
  EEA20601.1 135 KTVKLYCAKCEDIYNPKSSRHASiD 159
                 689***************9996643 PP

>> GCIP  Grap2 and cyclin-D-interacting
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   3.5   0.00077       3.5     136     163 ..     211     252 ..     199     266 .. 0.78

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.00077
                 HHHHHHHHH..............S-------------....- CS
        GCIP 136 eEmkellee..........edeeedededdldddede....e 163
                 eEmke l +          +++e+d +edd+ddd+ e    e
  EEA20601.1 211 EEMKERLNKlgidpgfiedSEDENDDFEDDIDDDKSEqigdE 252
                 68998888899999999988889999********88844440 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (268 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       858  (0.0478554); expected 358.6 (0.02)
Passed bias filter:                      697  (0.0388756); expected 358.6 (0.02)
Passed Vit filter:                        70  (0.00390429); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.57u 0.32s 00:00:00.88 Elapsed: 00:00:00.50
# Mc/sec: 1612.82
//
Query:       EEA20602.1  [L=293]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.5e-05   23.1   0.2    0.00025   21.0   0.2    2.0  1  Abhydrolase_3  alpha/beta hydrolase fold
     0.0096   15.6   0.0      0.026   14.2   0.0    1.6  2  Abhydrolase_1  alpha/beta hydrolase fold
  ------ inclusion threshold ------
      0.034   13.6   0.0      0.048   13.1   0.0    1.1  1  DUF3530        Protein of unknown function (DUF3530)


Domain annotation for each model (and alignments):
>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0   0.2   4.1e-08   0.00025       1      91 [.      34     144 ..      34     184 .. 0.74

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 4.1e-08
                    EEEE--STTT....S--TTTT..HHHHH.HHHHHHTSEEEEEE---TTTS-TTHHHHHHHHHHHHHHHTH.............HHHTETTCEEEEE CS
  Abhydrolase_3   1 lvyfHGGGfv....lgsldth..dalcr.elakelgavvvsvdYrlAPehpfPaavedalaalrwlaeqa.............welgadpsrivla 76 
                    ++y+HGG++     l ++  +    l + +l +   a   s+dYrl+P   +P+      ++   +a +              +++ a  +r +l 
     EEA20602.1  34 VIYIHGGAWRdntvLANSFLAtySILTQnSLIQTQVAGFASIDYRLSPHPNAPQDPSTTPSSQLRAARHPehfhdvqaaiaflQDKYAFGDRYMLI 129
                    69*******7443333332223233333134444455689*************9999999888888888889999*999998657778899***** PP

                    EETHHHHHHHHHHHH CS
  Abhydrolase_3  77 GdSaGGnlaaavalr 91 
                    G S+G++l+ +v++ 
     EEA20602.1 130 GHSCGATLSFQVVMN 144
                    **********99854 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.0   4.4e-06     0.026      43      91 ..      90     142 ..      61     147 .. 0.83
   2 ?   -2.1   0.0       0.4   2.4e+03     185     206 ..     228     249 ..     218     289 .. 0.67

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 4.4e-06
                    SSSTTTGB....CHHSHHHHHHHHHHHHHHCTTSSEE.EEEETHHHHHHHHHH CS
  Abhydrolase_1  43 Sspapacin...ddygtasvaddldrildalgddklt.lvGhSmGGmialaya 91 
                    S++++++     +  ++ +v++ + +++d++  +  + l+GhS+G ++++++ 
     EEA20602.1  90 STTPSSQLRaarHPEHFHDVQAAIAFLQDKYAFGDRYmLIGHSCGATLSFQVV 142
                    3333333337776678888******************************9875 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.4
                    HHHHHHHHHHCCHHHHHHHHHC CS
  Abhydrolase_1 185 alksieqwpttdsaklllrlre 206
                    ++  i+q++t+d+ ++l ++++
     EEA20602.1 228 GDSLINQPQTDDMLQVLKQWQG 249
                    5667888888888888888887 PP

>> DUF3530  Protein of unknown function (DUF3530)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0     8e-06     0.048     163     217 ..      90     144 ..      73     161 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 8e-06
     DUF3530 163 ekkaptdaearkahrervrarlqaaiaflnqrgae..nivllghgtgAywaarylae 217
                 +++++++   r+a   + +  +qaaiafl+ + a   + +l+gh  gA +  + + +
  EEA20602.1  90 STTPSSQ--LRAARHPEHFHDVQAAIAFLQDKYAFgdRYMLIGHSCGATLSFQVVMN 144
                 2333333..477888889999**********777699*************9999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (293 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       347  (0.0193541); expected 358.6 (0.02)
Passed bias filter:                      316  (0.0176251); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.30s 00:00:00.84 Elapsed: 00:00:00.50
# Mc/sec: 1779.53
//
Query:       EEA20603.1  [L=364]
Description: eukaryotic translation initiation factor 3 subunit EifCh, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.4e-09   35.6   0.1      2e-07   31.0   0.1    2.4  1  JAB       JAB1/Mov34/MPN/PAD-1 ubiquitin protease
  ------ inclusion threshold ------
      0.056   13.4   0.6        8.2    6.5   0.0    2.7  2  UCR_14kD  Ubiquinol-cytochrome C reductase complex 14kD subun


Domain annotation for each model (and alignments):
>> JAB  JAB1/Mov34/MPN/PAD-1 ubiquitin protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.0   0.1   2.2e-11     2e-07       4     114 ..       8     127 ..       5     131 .. 0.74

  Alignments for each domain:
  == domain 1  score: 31.0 bits;  conditional E-value: 2.2e-11
                 CEEEEEHHHHHHHHHHHHHHHHHTS--EEEEEEEESSSEEEEEEEEEEESEEEESSECE.......E......EEEHHHHHHHHHHHHHHHCTTSEEEE CS
         JAB   4 qavhleslvllkildhalrtekeeeevmGlliGelnddttveitnvfalpfeetekdvd.......a......vsldqeylekksellkklrgrervvG 89 
                  av++e+lv++ki++h ++         G l+G+  +d t+eitn f +p  e+  + +       a       + +  y  +++++l +++ + + vG
  EEA20603.1   8 AAVQVEALVVMKIIKHSSQSFPT--VATGSLVGLDVGD-TLEITNTFPFPIVEVPPESHfdtstpnAaaaaprAKANTAYQAEMIRMLREVNIDAQNVG 103
                 689********************..99***********.9999999998876543222200000112111111233456778888888888888***** PP

                 EEEESSSS-SS--HHHHHHHHHHHH CS
         JAB  90 WYhshpditvwlsevdvrtqalyqr 114
                 WY+s      +++ + ++ q+ yq+
  EEA20603.1 104 WYTSANMG-NFINLNVIENQFFYQK 127
                 **998877.9999999999999997 PP

>> UCR_14kD  Ubiquinol-cytochrome C reductase complex 14kD subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.0   0.00091       8.2       5      33 ..     158     186 ..     151     194 .. 0.86
   2 ?    4.0   0.8    0.0055        50      39      77 ..     273     312 ..     262     333 .. 0.83

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.00091
    UCR_14kD   5 kllkplakwyanaagyrklGLrydDllse 33 
                 ++++++++  + +  ++k GLry+D+l e
  EEA20603.1 158 QFMTAFKENKFTSEQLQKSGLRYQDILVE 186
                 788899999999999***********998 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.0055
    UCR_14kD  39 qeALrrLpeeeaydRvfR.lkrAlqlslkhklLPkeewtk 77 
                 q+ L+r +++ a  ++ R  + A+  +lk+  LP++ew+ 
  EEA20603.1 273 QRSLAREQQKIAAWQAKRkAENASRATLKQAPLPEDEWQR 312
                 677777778877777777356899**************75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (364 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       711  (0.0396564); expected 358.6 (0.02)
Passed bias filter:                      434  (0.0242066); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.44
# Mc/sec: 2470.02
//
Query:       EEA20604.1  [L=344]
Description: mitochondrial carrier protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.1e-44  149.4   2.8    8.5e-18   64.1   0.2    3.2  3  Mito_carr  Mitochondrial carrier protein
  ------ inclusion threshold ------
      0.016   15.7   1.9      0.037   14.6   0.1    2.3  2  PPDFL      Differentiation and proliferation regulator


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.1   0.0     6e-19   5.4e-15       9      95 ..       9      90 ..       4      92 .. 0.93
   2 !   29.2   0.0   7.1e-11   6.4e-07       7      94 ..     118     209 ..     114     212 .. 0.82
   3 !   64.1   0.2   9.5e-22   8.5e-18       7      95 ..     231     333 ..     226     335 .. 0.86

  Alignments for each domain:
  == domain 1  score: 55.1 bits;  conditional E-value: 6e-19
                HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCT CS
   Mito_carr  9 llaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlllk 95
                +laG++a+ +  +v++Pld++Ktr+q+ + ++ +     +  + + i +   +rgly+G++  ++ ++p+s++ f++ye +k++l+ 
  EEA20604.1  9 WLAGAIAAFTVDFVVYPLDTLKTRIQSPRYKELY-----TDAATGAIHRRSLFRGLYQGIWSIVIATIPSSGAFFTTYEGIKHILNS 90
                68*****************************998.....44678899999999******************************9986 PP

  == domain 2  score: 29.2 bits;  conditional E-value: 7.1e-11
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSS......HHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
   Mito_carr   7 kellaGglagavatlvttPldvvKtrlqtqkksskksksaa......ildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlll 94 
                  + +a+++a +v+ ++ tP +v+K   q+  ++ + + sa       +++vl++    +    l+rG++  + r+ p +a+++ l+e+l++ ++
  EEA20604.1 118 INSIASSIAECVSCFILTPAEVLKQNAQMVTSTDRRTSSATgtmkypTMQVLSTFR-AN-PIRLWRGYGTLVARNLPFTAMQLPLFEYLRERMQ 209
                 5789*************************666655554444666777887777654.44.568**************************99876 PP

  == domain 3  score: 64.1 bits;  conditional E-value: 9.5e-22
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSS..............HHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   7 kellaGglagavatlvttPldvvKtrlqtqkksskksksaa..............ildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkr 91 
                  + l++glag+va+++ttP+dv+Ktr+++++    +++ +a              ++ v k+iy++eG+rgl++G   +  ++a   +l++++yet + 
  EEA20604.1 231 ITALSAGLAGCVAAIITTPIDVIKTRVMLAAAGDGEQHASAgsgtsstspsrsrsAFTVGKEIYQKEGMRGLFKGGFLRAGWTALGFGLYLSAYETGRM 329
                 56799************************666655555444566666677778889****************************************999 PP

                 HHCT CS
   Mito_carr  92 lllk 95 
                 ++ k
  EEA20604.1 330 YFEK 333
                 8877 PP

>> PPDFL  Differentiation and proliferation regulator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.1   4.1e-06     0.037       1      47 [.      68     114 ..      68     121 .. 0.93
   2 ?   -0.5   0.1       0.2   1.8e+03      23      46 ..     276     299 ..     258     305 .. 0.71

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 4.1e-06
       PPDFL   1 maaiPssgsLvathdYyrrrlgstssnsscgsaeypgeaiphhpGLp 47 
                 +a+iPssg++ +t +  ++ l s+++  s +s+   g+ +p +  Lp
  EEA20604.1  68 IATIPSSGAFFTTYEGIKHILNSAATRNSSDSTTTGGNLLPFKHSLP 114
                 599***********************99**********999988887 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.2
       PPDFL  23 stssnsscgsaeypgeaiphhpGL 46 
                 s++s s  +sa  +g +i ++ G+
  EEA20604.1 276 SSTSPSRSRSAFTVGKEIYQKEGM 299
                 445555566777788888777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (344 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       604  (0.0336884); expected 358.6 (0.02)
Passed bias filter:                      451  (0.0251548); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.35s 00:00:00.99 Elapsed: 00:00:00.56
# Mc/sec: 1835.29
//
Query:       EEA20605.1  [L=2836]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    0.00067   19.7  86.3      0.002   18.1  19.2   26.4 26  Trypan_PARP  Procyclic acidic repetitive protein (PARP)


Domain annotation for each model (and alignments):
>> Trypan_PARP  Procyclic acidic repetitive protein (PARP)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -7.0   8.8         1   1.8e+04      22      90 ..     193     241 ..     163     255 .. 0.42
   2 ?   -2.8   0.7      0.33   5.9e+03      75      96 ..     429     450 ..     383     481 .. 0.47
   3 ?   -2.9   6.4      0.34     6e+03      64      97 ..     503     540 ..     457     565 .. 0.54
   4 ?   -6.3  20.7         1   1.8e+04      59     111 ..     611     681 ..     569     689 .. 0.64
   5 !    3.0  20.6    0.0052        93      90     111 ..     719     740 ..     697     744 .. 0.69
   6 ?  -32.0  70.4         1   1.8e+04      59     111 ..     720     797 ..     717     861 .. 0.68
   7 ?   -4.8  44.4         1   1.8e+04      57     111 ..     834     913 ..     812     917 .. 0.73
   8 ?   -3.4  51.4      0.48   8.5e+03      59     111 ..     893     970 ..     873     978 .. 0.58
   9 !   17.2  23.4   2.1e-07    0.0038      81     110 ..    1012    1041 ..     984    1048 .. 0.52
  10 !   12.9  13.3   4.4e-06     0.079      91     110 ..    1082    1101 ..    1055    1111 .. 0.53
  11 !   16.2  16.2   4.3e-07    0.0077      88     111 ..    1137    1160 ..    1115    1167 .. 0.62
  12 ?   -9.9  43.7         1   1.8e+04      61     112 ..    1200    1271 ..    1179    1280 .. 0.59
  13 ?   -8.1  45.4         1   1.8e+04      59     110 ..    1256    1327 ..    1232    1333 .. 0.54
  14 ?   -7.1  42.2         1   1.8e+04      59     112 ..    1312    1392 ..    1306    1401 .. 0.70
  15 !   18.1  19.2   1.1e-07     0.002      82     112 ..    1433    1463 ..    1412    1468 .. 0.70
  16 !   14.3  18.7   1.7e-06     0.031      53      82 ..    1495    1527 ..    1471    1568 .. 0.48
  17 ?   -9.6   6.0         1   1.8e+04      88     102 ..    1622    1636 ..    1605    1646 .. 0.35
  18 !   17.5  27.7   1.7e-07     0.003      38     112 ..    1783    1852 ..    1770    1857 .. 0.43
  19 ?    0.0  12.7     0.043   7.8e+02      65      78 ..    1892    1905 ..    1868    1912 .. 0.59
  20 ?   -5.4  42.8         1   1.8e+04      61     112 ..    1892    1967 ..    1888    1974 .. 0.53
  21 ?    1.5  18.1     0.015   2.6e+02      88     113 ..    2002    2026 ..    1979    2032 .. 0.60
  22 ?   -8.2  43.7         1   1.8e+04      59     113 ..    2007    2084 ..    2003    2089 .. 0.62
  23 ?   -1.6  22.7      0.14   2.5e+03      59     116 ..    2121    2150 ..    2095    2164 .. 0.50
  24 ?  -10.9  19.7         1   1.8e+04      63     102 ..    2180    2218 ..    2154    2234 .. 0.53
  25 ?   -3.8   2.2      0.66   1.2e+04      60     100 ..    2498    2534 ..    2492    2553 .. 0.37
  26 ?   -4.5   2.1         1   1.8e+04      63      77 ..    2594    2608 ..    2548    2641 .. 0.51

  Alignments for each domain:
  == domain 1  score: -7.0 bits;  conditional E-value: 1
  Trypan_PARP  22 vgfaaaaegpedkgltkggkgkekgtkvsdddtngtdpepepepepepepepepepepetepeeepepe 90 
                  vg +a  ++  d+g  k   g ++ t  s+   +  + e e e                   ee  ++e
   EEA20605.1 193 VGGSAGGDDDGDNG-DKNDDGWGEATSSSKKKKSKKQQEEEEE-------------------EERKKKE 241
                  22222222222222.1112222222222221111111111111...................1111111 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.33
  Trypan_PARP  75 pepepetepeeepepepepepe 96 
                   +  p    + + ++e  pep+
   EEA20605.1 429 DDWGPWGVKKTSKKEELAPEPK 450
                  1222222222222333333332 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 0.34
  Trypan_PARP  64 epepepepepepepep....etepeeepepepepepep 97 
                  e    p+pep  +       +++ ++ +++e+epep  
   EEA20605.1 503 ETALAPDPEPVIDNVWavpvKKDKKKAGKKEAEPEPVQ 540
                  33333333333222212223344555555566665532 PP

  == domain 4  score: -6.3 bits;  conditional E-value: 1
  Trypan_PARP  59 pepepepepepepepe.pepep..................etepeeepepepepepepepepepe.pepepep 111
                   e  pepepep pe e p+  +                  e+e  +++ p     p+p  epep+  epep p
   EEA20605.1 611 KEVVPEPEPEPVPEVEkPK--NhefwdgwdtwtplqrkkkEKEAVKKGIPARIEIPQPVVEPEPKlVEPEPTP 681
                  3444444444444444322..2457999998888876544333334444433334555555555323455544 PP

  == domain 5  score: 3.0 bits;  conditional E-value: 0.0052
  Trypan_PARP  90 epepepepepepepepepepep 111
                  +  pepepep+pepepep pep
   EEA20605.1 719 DIAPEPEPEPQPEPEPEPAPEP 740
                  4456666666666666666666 PP

  == domain 6  score: -32.0 bits;  conditional E-value: 1
  Trypan_PARP  59 pepepepepepepepepepep.....................etepeeep....epepepepepepepepepepepep 111
                    pepepep+pepepep pep                     e e  + +    +++  pepep+pe  pepep pep
   EEA20605.1 720 IAPEPEPEPQPEPEPEPAPEPpknhefwdgwqswgpvtkrkkEREAVKLGipplNENIAPEPEPQPELAPEPEPVPEP 797
                  456666666666666666666668889999998888876655222222111111233344444444444555555555 PP

  == domain 7  score: -4.8 bits;  conditional E-value: 1
  Trypan_PARP  57 tdpepepepepepepepepepep.....................etepeeep....epepepepepepepepepepepep 111
                    p+pepep+pep pepep p+p                     e e  + +    +++  pepepep+p pepep pep
   EEA20605.1 834 IAPQPEPEPQPEPAPEPEPAPKPpknhefwdgwqtwgpvtkrkkEREAVKLGipplNENITPEPEPEPQPVPEPEPIPEP 913
                  47889999999999999999988899*********999987755333222212122456679999999999999999998 PP

  == domain 8  score: -3.4 bits;  conditional E-value: 0.48
  Trypan_PARP  59 pepepepepepepepepepep.....................etepeeepe....pepepepepepepepepepepep 111
                    pepepep+p pepep pep                     e+e  +++     ++  pepepepepepepepepep
   EEA20605.1 893 ITPEPEPEPQPVPEPEPIPEPpknhefwngwqdwtpsarkkkEKEAIKKGIppliEDIAPEPEPEPEPEPEPEPEPEP 970
                  34555555555555555555555899*******999998766333322221112233445555555555555555554 PP

  == domain 9  score: 17.2 bits;  conditional E-value: 2.1e-07
  Trypan_PARP   81 tepeeepepepepepepepepepepepepe 110 
                     pe+epepepepepepepepepepep pe
   EEA20605.1 1012 VVPEPEPEPEPEPEPEPEPEPEPEPEPIPE 1041
                   333333333333333333333333333333 PP

  == domain 10  score: 12.9 bits;  conditional E-value: 4.4e-06
  Trypan_PARP   91 pepepepepepepepepepe 110 
                   pepepepepepepepep pe
   EEA20605.1 1082 PEPEPEPEPEPEPEPEPIPE 1101
                   22222222222222222222 PP

  == domain 11  score: 16.2 bits;  conditional E-value: 4.3e-07
  Trypan_PARP   88 epepepepepepepepepepepep 111 
                   e+ pepepepepepepepepepep
   EEA20605.1 1137 EDIPEPEPEPEPEPEPEPEPEPEP 1160
                   344555555555555555555555 PP

  == domain 12  score: -9.9 bits;  conditional E-value: 1
  Trypan_PARP   61 pepepepepepepepepep................etepeeepep....epepepepepepepepepepepg 112 
                   pepepepepep p p+  +                e+e  +++ p    +  pep  epepep+pepepep 
   EEA20605.1 1200 PEPEPEPEPEPAPPPKNHEfwdgwqdwsssqrkkkEKEAVKKGIPllivDIAPEPVVEPEPEPDPEPEPEPA 1271
                   445555554444444444489999999998877653333333322222233455555555555555555543 PP

  == domain 13  score: -8.1 bits;  conditional E-value: 1
  Trypan_PARP   59 pepepepepepepepepepep....................etepeeepepepepepepepepepepepepe 110 
                   +epepep+pepepep p p p                    e+e  +++ p  +   epep pepepepepe
   EEA20605.1 1256 VEPEPEPDPEPEPEPAPPPPPknhefwddwdswtplqrkkkEKEAIKKNIPPRQEIVEPEPIPEPEPEPEPE 1327
                   3444444444444444333337799*****999888865432222222111111223444444555555554 PP

  == domain 14  score: -7.1 bits;  conditional E-value: 1
  Trypan_PARP   59 pepepepepepepepe.pepep...........................etepeeepepepepepepepepepepepepepg 112 
                   +epep pepepepepe p                               + + +  +  ep pepepe epep +epepep 
   EEA20605.1 1312 VEPEPIPEPEPEPEPEqPRN-HefwtgwqdwsskdrkkkekeaklkgipDLQEDLPSALEPVPEPEPELEPEPAAEPEPEPE 1392
                   45666666666666663333.25899*********99998766665533222222334588999999999999999999985 PP

  == domain 15  score: 18.1 bits;  conditional E-value: 1.1e-07
  Trypan_PARP   82 epeeepepepepepepepepepepepepepg 112 
                    p  +p  epepepepepepepepepepep 
   EEA20605.1 1433 PPALDPAAEPEPEPEPEPEPEPEPEPEPEPR 1463
                   4556677777777777777777777777774 PP

  == domain 16  score: 14.3 bits;  conditional E-value: 1.7e-06
  Trypan_PARP   53 dtngt...dpepepepepepepepepepepete 82  
                   d+n     dpepepepe epepepepepep  e
   EEA20605.1 1495 DVNLKpalDPEPEPEPELEPEPEPEPEPEPILE 1527
                   222222112222222222222222222222222 PP

  == domain 17  score: -9.6 bits;  conditional E-value: 1
  Trypan_PARP   88 epepepepepepepe 102 
                   e++  p p   + p 
   EEA20605.1 1622 EEDLAPPPPAPTPPA 1636
                   222222111111111 PP

  == domain 18  score: 17.5 bits;  conditional E-value: 1.7e-07
  Trypan_PARP   38 kggkgkekgtkvsdddtngt.dpepep.epepepepepepepepetepeeepepepepepepepepepepepepepg 112 
                     g gk++ tk s+       ++ pep e+e   e  p       + pe+ep +epepepepepepepepep p p 
   EEA20605.1 1783 DAGYGKQRLTKSSSSKKAIPeETPPEPvEEEISHESIP------GSFPEPEP-EEPEPEPEPEPEPEPEPEPAPAPE 1852
                   46778877787776443322122222211111122222......22222222.234444444444444444444443 PP

  == domain 19  score: 0.0 bits;  conditional E-value: 0.043
  Trypan_PARP   65 pepepepepepepe 78  
                   pepepepepep pe
   EEA20605.1 1892 PEPEPEPEPEPVPE 1905
                   12222222222222 PP

  == domain 20  score: -5.4 bits;  conditional E-value: 1
  Trypan_PARP   61 pepepepepepepe.pepep......................etepeeepepepepepepep...epepepepepepg 112 
                   pepepepepep pe p+  +                      +  p     ++  pepepep   epepepepep p 
   EEA20605.1 1892 PEPEPEPEPEPVPEaPKNHEfwngwqdwtpsarrkkekeaikKGIPSLI--EDIAPEPEPEPepvEPEPEPEPEPVPE 1967
                   6666666666666633333379999999999988774433221112222..233444444440034455555555444 PP

  == domain 21  score: 1.5 bits;  conditional E-value: 0.015
  Trypan_PARP   88 epepepepepepepepepepepepga 113 
                    ++  pepepe+ep  epepepep a
   EEA20605.1 2002 IEDIAPEPEPEAEPV-EPEPEPEPEA 2026
                   456677777777774.5555555544 PP

  == domain 22  score: -8.2 bits;  conditional E-value: 1
  Trypan_PARP   59 pepepepepepepepepepep.....................etepeeepe....pepepepepepepepepepepepga 113 
                   pepepe ep  epepepepe                      e+e  + +     ++  pepepe+ep  epepepep a
   EEA20605.1 2007 PEPEPEAEPV-EPEPEPEPEApknhkfwdgwqdwtpsarrkkEKEAIKRGIpsliEDIAPEPEPEAEPV-EPEPEPEPEA 2084
                   4555555553.666666666666789******9999887765333333332112256789999999995.6666666655 PP

  == domain 23  score: -1.6 bits;  conditional E-value: 0.14
  Trypan_PARP   59 pepepep.epepepepepepepetepeeepepepepepepepepepepepepepgaatl 116 
                     pepep epepepepep p p                             pep   + 
   EEA20605.1 2121 IAPEPEPvEPEPEPEPEPAPPP-----------------------------PEPSKKSK 2150
                   2333333233333333333332.............................33333333 PP

  == domain 24  score: -10.9 bits;  conditional E-value: 1
  Trypan_PARP   63 pepepepepepepepepetepeeepepepepepepepepe 102 
                    ep  ep    e+  e+ +  ee p++ p p pep +e  
   EEA20605.1 2180 EEPVVEPPAAQEAAAEE-STSEEVPPKPPTPPPEPTTESS 2218
                   23333333333333333.4455555555555555555543 PP

  == domain 25  score: -3.8 bits;  conditional E-value: 0.66
  Trypan_PARP   60 epepep.epepepepepepepetepeeepepepepepepepe 100 
                   epe+ +  p  +   e+e ++     +  + e     +pe++
   EEA20605.1 2498 EPERRKsRPRRDEMTETERDE-----KRVKRERRRSVKPETD 2534
                   222221012222222222211.....1111222222222222 PP

  == domain 26  score: -4.5 bits;  conditional E-value: 1
  Trypan_PARP   63 pepepepepepepep 77  
                   +e e   e e e++ 
   EEA20605.1 2594 RERELREEMEREAQR 2608
                   122222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2836 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1807  (0.100786); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                       156  (0.00870099); expected 17.9 (0.001)
Passed Fwd filter:                        68  (0.00379274); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 2.86u 0.44s 00:00:03.30 Elapsed: 00:00:00.79
# Mc/sec: 10900.10
//
Query:       EEA20606.1  [L=347]
Description: HMG box protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    5.2e-10   39.6   0.1    5.2e-10   39.6   0.1    3.6  3  HMG_box    HMG (high mobility group) box
    1.8e-07   31.6   0.2    1.8e-07   31.6   0.2    3.5  3  HMG_box_2  HMG-box domain
    0.00064   19.9   0.2     0.0022   18.1   0.2    2.0  1  FliG_C     FliG C-terminal domain
  ------ inclusion threshold ------
       0.96    8.4   7.0          2    7.4   7.0    1.5  1  FAM199X    Protein family FAM199X
          5    6.8  10.5        5.5    6.7   8.8    1.6  1  DUF445     Protein of unknown function (DUF445)
        7.4    3.9   8.0         10    3.4   8.0    1.1  1  HHV6-IE    Human herpesvirus 6 immediate early protein


Domain annotation for each model (and alignments):
>> HMG_box  HMG (high mobility group) box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   2.5       5.5   1.6e+04      18      33 ..     103     118 ..      96     137 .. 0.61
   2 ?    3.9   1.7     0.024        71       7      68 ..     160     217 ..     153     218 .. 0.73
   3 !   39.6   0.1   1.7e-13   5.2e-10       1      67 [.     260     324 ..     260     326 .. 0.94

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 5.5
                 HHHHHSTTS-HHHHHH CS
     HMG_box  18 klkaenPelknaeisk 33 
                   k+  P+ k++ + k
  EEA20606.1 103 AAKKRKPKKKVKKVRK 118
                 4455555555555544 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.024
                 HHHHHHHHHHHHHHHHSTTS-HHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHH CS
     HMG_box   7 afflfskeqraklkaenPelknaeiskklgekWkalseeeKkkYeekaekekaryekekpey 68 
                 a++lf++e+ + +  e      +++ + +++++++l+e +++   ++a+k+ ++ e++ +e+
  EEA20606.1 160 AWNLFVSEKLKGVDREAR---SSAL-RDIAAQYRELPEYQREILNQEASKLSKENEAKLKEW 217
                 666666666555555543...3333.346789******************999999888877 PP

  == domain 3  score: 39.6 bits;  conditional E-value: 1.7e-13
                 --SS--HHHHHHHHHHHHHHHHSTTS-HHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHH CS
     HMG_box   1 pkRplsafflfskeqraklkaenPelknaeiskklgekWkalseeeKkkYeekaekekaryekekpe 67 
                 +kRp+saf+ f+ke  a+   e  +l ++eis ++ ++W + s++eK+ Y  kae++++ry  e+++
  EEA20606.1 260 VKRPVSAFLWFFKERVAT--GEYRGLPVTEISERVKAEWVNTSDSEKQLYLTKAEEDRQRYITEYRD 324
                 69***********98775..8999*************************************999975 PP

>> HMG_box_2  HMG-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.3   4.3         6   1.8e+04      53      69 ..     118     134 ..      86     138 .. 0.65
   2 ?    1.5   1.0      0.16   4.6e+02       6      65 ..     156     210 ..     150     217 .. 0.69
   3 !   31.6   0.2   6.1e-11   1.8e-07       5      68 ..     261     321 ..     258     325 .. 0.89

  Alignments for each domain:
  == domain 1  score: -4.3 bits;  conditional E-value: 6
                 HHHHHHHHHHHHHHH-S CS
   HMG_box_2  53 kYeekAkedkkrydrea 69 
                 k  e A e++ ++++e+
  EEA20606.1 118 KLSEDALEKRRKQRQEQ 134
                 34455666666666665 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.16
                 SS--HHHHHHHTTHHHHHHHT---SSHHHHTGGGHHHHHHS-HHHHHHHHHHHHHHHHHH CS
   HMG_box_2   6 aarnAYalfvqemipelkrkGnpviglaevsklcsekWkalseeeKekYeekAkedkkry 65 
                 +++ A++lfv e+ + + r+    +    + + +  + + l+e ++e  +++A ++ k+ 
  EEA20606.1 156 RSPIAWNLFVSEKLKGVDRE-ARSS----ALRDIAAQYRELPEYQREILNQEASKLSKEN 210
                 56778888888887777777.4444....4445567788899999998888887766555 PP

  == domain 3  score: 31.6 bits;  conditional E-value: 6.1e-11
                 -SS--HHHHHHHTTHHHHHHHT---SSHHHHTGGGHHHHHHS-HHHHHHHHHHHHHHHHHHHH- CS
   HMG_box_2   5 kaarnAYalfvqemipelkrkGnpviglaevsklcsekWkalseeeKekYeekAkedkkrydre 68 
                 k++ +A++ f +e+ ++   +G pv +++e +k    +W + s++eK+ Y  kA ed++ry  e
  EEA20606.1 261 KRPVSAFLWFFKERVATGEYRGLPVTEISERVK---AEWVNTSDSEKQLYLTKAEEDRQRYITE 321
                 899******************999877766665...69**********************9776 PP

>> FliG_C  FliG C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.2   7.4e-07    0.0022       1     102 [.     146     245 ..     146     251 .. 0.91

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 7.4e-07
                 HHHHHH-HHHHHHHHHHHS-GGGGGGS-HHHHHHHHTTS-HHHHHHHHCTS-HHHHHHHHTTS-HHHHHHHHHHHHHC-S--HHHHHHHHHHHHHHHHH CS
      FliG_C   1 esLeeedpelaeeirkkmftfedlvrlddraiqrllrevdkedLalaLkgaseelrekilsnmSkraaemlreelealgpvrlsdveeaqkeivaiirr 99 
                 esL++e+p+l + i  ++f+ e+l  +d++a  + lr++ ++     L   ++e+ +   s++Sk++ ++l+e + +  p r++++++a+k + + + +
  EEA20606.1 146 ESLKKEEPKLRSPIAWNLFVSEKLKGVDREARSSALRDIAAQ--YRELPEYQREILNQEASKLSKENEAKLKEWVHSYSPLRIKQANAARKLLPKYMAK 242
                 689************************************998..58899*****************************************987777766 PP

                 HHC CS
      FliG_C 100 lee 102
                  e+
  EEA20606.1 243 HEK 245
                 665 PP

>> FAM199X  Protein family FAM199X
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   7.0   0.00067         2     221     298 ..      64     144 ..      32     152 .. 0.65

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.00067
     FAM199X 221 asmvssassstasvgssaansaanisra..hsdsnls.saaerirdskkrskqrklqqkalrkrqlkeqrqarkerlsglf 298
                 a++  +  s+t++++s+ a+      r    s+ +    aa++ +  kk  k rkl + al kr+ + q q  k+ +  l+
  EEA20606.1  64 ATFQRNQYSTTTTTTSADASKPKPRGRPpkSSEEKPKkKAAKKRKPKKKVKKVRKLSEDALEKRRKQRQEQKVKDTIKSLI 144
                 44444444444444444333333333321123333333777777778888899************9999999999887765 PP

>> DUF445  Protein of unknown function (DUF445)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   8.8    0.0018       5.5     217     303 ..     102     188 ..      41     233 .. 0.54

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0018
      DUF445 217 liadllndpelaakveklkkkklsdlevqeyeealwealkdlllkdlneeesllrerisklleklgeklaed.pklreklnkflenaa 303
                  +a+ ++ ++  +kv kl ++ l++ ++q++e+++ + +k+l+ ++l++ee  lr++i+  l  ++ekl+   ++ r++  +++  + 
  EEA20606.1 102 KAAKKRKPKKKVKKVRKLSEDALEKRRKQRQEQKVKDTIKSLIAESLKKEEPKLRSPIAWNL-FVSEKLKGVdREARSSALRDIAAQY 188
                 34444444445556666666666666666666666666666666666665544444443222.2333333222222222222221111 PP

>> HHV6-IE  Human herpesvirus 6 immediate early protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   8.0    0.0035        10     690     771 ..      42     126 ..      28     138 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.0035
     HHV6-IE 690 iadsdsavrtnnihmnstde.ntpfskslysppevtpskedvkte..kivavsqkckskkrvakrknvsiksskskkikldrlpe 771
                 +ad+ +av +n+  + + ++  + f +  ys    t s +  k++     + s + k+kk++ak+++   k  k +k+  d l +
  EEA20606.1  42 LADTRAAVFSNKTRVSTLNQlGATFQRNQYSTTTTTTSADASKPKprGRPPKSSEEKPKKKAAKKRKPKKKVKKVRKLSEDALEK 126
                 788899999999999888773578**************9998876215678999************************9999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (347 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2257  (0.125885); expected 358.6 (0.02)
Passed bias filter:                      579  (0.032294); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.66u 0.32s 00:00:00.98 Elapsed: 00:00:00.50
# Mc/sec: 2075.26
//
Query:       EEA20607.1  [L=82]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.9e-05   23.3   0.0    6.4e-05   22.9   0.0    1.2  1  Inhibitor_I78   Peptidase inhibitor I78 family
     0.0022   18.6   0.0     0.0035   18.0   0.0    1.5  1  potato_inhibit  Potato inhibitor I family


Domain annotation for each model (and alignments):
>> Inhibitor_I78  Peptidase inhibitor I78 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.0   7.2e-09   6.4e-05       7      65 .]      22      82 .]      18      82 .] 0.87

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 7.2e-09
  Inhibitor_I78  7 qslvGqpaedsesad..vlkrsnsdsvRvlkPGqvvtleynpaRlniivegaGkisalrCG 65
                    +l+G++ +ds++ +  + k+      R+l P   +  +y+p Rl i v+++G +  +r G
     EEA20607.1 22 DELMGKKLTDSKTDElsFAKQDLPPNHRILGPDTTMIPDYQPDRLIIRVDDEGTVRDVRYG 82
                   689*********986225678888899**************************99888765 PP

>> potato_inhibit  Potato inhibitor I family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   3.9e-07    0.0035      28      59 ..      47      78 ..      17      80 .. 0.76

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 3.9e-07
  potato_inhibit 28 vvevvpegspvtadfrcnRVrvfvdengiVaq 59
                    + +++ +++++++d++++R ++ vd++g+V  
      EEA20607.1 47 NHRILGPDTTMIPDYQPDRLIIRVDDEGTVRD 78
                    45689999*********************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (82 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       342  (0.0190752); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.31s 00:00:00.76 Elapsed: 00:00:00.48
# Mc/sec: 518.24
//
Query:       EEA20608.1  [L=281]
Description: hypothetical protein PMAA_044410 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (281 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       504  (0.0281109); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.30s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 1821.79
//
Query:       EEA20609.1  [L=236]
Description: hypothetical protein PMAA_044420 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00056   19.8   0.0      0.001   18.9   0.0    1.4  1  Tmemb_9   TMEM9
  ------ inclusion threshold ------
      0.041   13.6   0.2      0.071   12.8   0.2    1.5  1  FAM176    FAM176 family
       0.18   12.3   0.0       0.36   11.3   0.0    1.5  1  FAM163    FAM163 family


Domain annotation for each model (and alignments):
>> Tmemb_9  TMEM9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.0   1.8e-07     0.001      51     138 ..      50     157 ..      36     162 .. 0.64

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 1.8e-07
     Tmemb_9  51 kvvviivivvislLviYmlflllldpllnkr...........kkkasyqehtnee...................detseslssasqs........lelr 111
                   ++i  i + +lL++ + +l+  d  + +r           k                                        as++        + ++
  EEA20609.1  50 AGIIIGSIFITALLLCLIAYLVSHDNCITRRgwfkrrreqknK-----------GksqylspqedeealtkrasF--------ASEResimfsrsRASS 129
                 5589999**********************99665333333221...........223355554444454433331........2222345443214444 PP

     Tmemb_9 112 arsnvlnrvehqqdkWkrqvk.eQrrni 138
                    +v++ v+h q++   q + eQr+ +
  EEA20609.1 130 FTFAVVEDVDHSQRRMSSQTEaEQRKGL 157
                 4579************999975788865 PP

>> FAM176  FAM176 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.2   1.2e-05     0.071      34     115 ..      62     143 ..      33     155 .. 0.64

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.2e-05
      FAM176  34 LlltLcl.lviriscrkdlerlkkkkkklkeesekasededeeeeeeeedsseseaeeelsefertlsvnvftsaeelerAqR 115
                 Lll L++ lv +  c ++    k++++++++ ++++ + +++ee  ++  s  se e+ + + +r+ s  +f+ +e++++ qR
  EEA20609.1  62 LLLCLIAyLVSHDNCITRRGWFKRRREQKNKGKSQYLSPQEDEEALTKRASFASERESIMFSRSRA-SSFTFAVVEDVDHSQR 143
                 555555435556667666664444444444444445455555544555555555544444444444.7888999999999998 PP

>> FAM163  FAM163 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0     6e-05      0.36       7      58 ..      52     115 ..      50     156 .. 0.61

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 6e-05
      FAM163   7 vitGGilatviLLciiavL.....CyCRLqYYCCkkdeseee.......eeeepefavleplac 58 
                 +i G i+ t +LLc+ia L     C+ R  ++  +++++++        +e+e+ +++   +a+
  EEA20609.1  52 IIIGSIFITALLLCLIAYLvshdnCITRRGWFKRRREQKNKGksqylspQEDEEALTKRASFAS 115
                 689**************99888889999999999999998874444322222222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (236 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       848  (0.0472977); expected 358.6 (0.02)
Passed bias filter:                      566  (0.031569); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.30s 00:00:00.81 Elapsed: 00:00:00.48
# Mc/sec: 1478.00
//
Query:       EEA20610.1  [L=1294]
Description: VPS9 domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.4e-17   63.8   0.0    3.3e-17   62.6   0.0    1.6  1  VPS9             Vacuolar sorting protein 9 (VPS9) domain
      1e-15   57.6   0.1    3.4e-14   52.7   0.0    3.5  4  Ank_5            Ankyrin repeats (many copies)
    3.8e-11   43.4   0.4     0.0065   17.0   0.0    4.5  5  Ank_2            Ankyrin repeats (3 copies)
    4.8e-07   29.7   0.0    2.1e-06   27.7   0.0    2.1  2  PX               PX domain
     0.0001   22.7   0.0        1.5    9.5   0.0    4.1  4  Ank_4            Ankyrin repeats (many copies)
    0.00027   21.2   0.7        2.6    8.6   0.0    4.1  4  Ank              Ankyrin repeat
      0.002   18.5   0.1        4.2    8.3   0.0    5.1  5  Ank_3            Ankyrin repeat
     0.0042   16.8   0.0      0.075   12.7   0.0    2.3  2  SRP54            SRP54-type protein, GTPase domain
  ------ inclusion threshold ------
      0.041   13.6   0.0         12    5.5   0.0    2.6  2  ThiJ_like        ThiJ/PfpI family-like
      0.058   13.3   1.2        0.2   11.5   1.2    1.9  1  BsuBI_PstI_RE_N  BsuBI/PstI restriction endonuclease HTH doma
       0.27   11.3   2.1       0.38   10.8   0.5    2.0  2  Flavin_Reduct    Flavin reductase like domain


Domain annotation for each model (and alignments):
>> VPS9  Vacuolar sorting protein 9 (VPS9) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.6   0.0     2e-20   3.3e-17       5      99 ..     372     476 ..     368     480 .. 0.94

  Alignments for each domain:
  == domain 1  score: 62.6 bits;  conditional E-value: 2e-20
        VPS9   5 seeLkklseaksPreKlkcllrtieeiteav.........skseegeslgaDdlLPiliyviikssppnlysnvqfikrFr.sktllegeegYylttle 93 
                 +e ++k++ a +P+++l++ll+ti+ +t +          +k+ ++ +++aD l ++l++v+i+s++++l++ + ++++F   ++  +ge gY+l+tle
  EEA20610.1 372 VEAFRKMNDATCPQDMLDVLLATIKAVTVSEesdrslhssEKQPPAFTVNADILVSMLLVVVIRSQVRRLQARLLYMQHFIfVDDVESGEMGYALSTLE 470
                 5789************************777*******9888888899*********************************99**************** PP

        VPS9  94 aavefi 99 
                 a+++++
  EEA20610.1 471 AVLTYL 476
                 ***998 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.0       1.6   2.6e+03       9      28 ..     678     697 ..     674     704 .. 0.78
   2 ?   -3.6   0.0       9.9   1.6e+04      45      53 ..     754     762 ..     752     762 .. 0.67
   3 ?   -0.8   0.0       1.3   2.1e+03      10      23 ..     799     812 ..     795     813 .. 0.82
   4 !   52.7   0.0   2.1e-17   3.4e-14       1      56 []     822     877 ..     821     877 .. 0.96

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 1.6
       Ank_5   9 vnrldgggntpLhvAakyga 28 
                 + +++++g+t L  A+ + +
  EEA20610.1 678 LEDTNRDGTTLLSAAVQHAN 697
                 668999******99998544 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 9.9
       Ank_5  45 tdsrGltal 53 
                 +d++G+t+l
  EEA20610.1 754 RDKHGQTPL 762
                 567777775 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 1.3
       Ank_5  10 nrldgggntpLhvA 23 
                 ++ d +gnt Lh+ 
  EEA20610.1 799 DHVDLKGNTLLHIV 812
                 567999******85 PP

  == domain 4  score: 52.7 bits;  conditional E-value: 2.1e-17
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltaldlA 56 
                 L+e++ +d+n+++++++tpL+vA+kyg+ d++r+L+ ++++d+ +t+srGlta++lA
  EEA20610.1 822 LAECD-CDPNATNERKFTPLMVASKYGRVDLMRRLFaDPRVDTHITESRGLTAIELA 877
                 66777.*************************************************99 PP

>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   1.9e-05     0.032      21      71 ..     643     707 ..     623     718 .. 0.75
   2 ?    4.6   0.0      0.03        50      24      65 ..     723     771 ..     704     789 .. 0.56
   3 !   17.0   0.0   4.2e-06    0.0069      24      74 ..     802     857 ..     737     867 .. 0.74
   4 !   17.0   0.0     4e-06    0.0065      11      60 ..     816     877 ..     808     895 .. 0.75
   5 ?   -2.9   0.0       6.9   1.1e+04      12      36 ..     919     949 ..     915     965 .. 0.61

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 1.9e-05
       Ank_2  21 dpnkngktaLhyAakngnleivklLle...h.........adndgrtpLhyAarsghleivk....l 71 
                 dp   g ++ + A+++ +  ++k+Ll+   +         +++dg+t L +A+++ + ++v+    +
  EEA20610.1 643 DP--AGDSVPMMAVESHQPAALKYLLSlqeYysidviledTNRDGTTLLSAAVQHANRKVVDiitdF 707
                 33..47899999***999999*****865526777777677799**********9777999944444 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.03
       Ank_2  24 k...ngktaLhyAakngnleivklLleh.....adndgrtpLhyAars.gh 65 
                 k    g+t+ hy  ++ +l  ++ L +       d++g+tpL++ +rs +h
  EEA20610.1 723 KediRGRTVAHYLFSAPYL--MSSLGSLlpwqkRDKHGQTPLFAICRSyDH 771
                 1445677777777776532..322222133335668888888877776533 PP

  == domain 3  score: 17.0 bits;  conditional E-value: 4.2e-06
       Ank_2  24 k.ngktaLhyAakngnleiv.klLleh......adndgrtpLhyAarsghleivklLle 74 
                 + +g+t Lh+       ei+ ++L e       +++   tpL++A+++g+ ++++ L+ 
  EEA20610.1 802 DlKGNTLLHIVSDP---EIItRILAECdcdpnaTNERKFTPLMVASKYGRVDLMRRLFA 857
                 25789999987664...776377777465655444667799999999999999998883 PP

  == domain 4  score: 17.0 bits;  conditional E-value: 4e-06
       Ank_2  11 elvklLl..egadpn..k.ngktaLhyAakngnleivklLleh.......adndgrtpLhyA 60 
                 e++  +l  + +dpn  +  + t+L++A k+g +++++ L +        +++ g t++ +A
  EEA20610.1 816 EIITRILaeCDCDPNatNeRKFTPLMVASKYGRVDLMRRLFADprvdthiTESRGLTAIELA 877
                 5666666477788887537889**********99***9999855544445558899999888 PP

  == domain 5  score: -2.9 bits;  conditional E-value: 6.9
       Ank_2  12 lvklLl.egadpn.k....ngktaLhyAakn 36 
                 +v+++l +ga ++ +    ng t  ++ +++
  EEA20610.1 919 TVRFILkSGAQASsDttsvNGTTYAITTCRR 949
                 5666666665555423356777777777776 PP

>> PX  PX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       3.3   5.4e+03      59     102 ..     153     200 ..     147     232 .. 0.68
   2 !   27.7   0.0   1.3e-09   2.1e-06      35     110 ..     945    1021 ..     929    1024 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 3.3
                 TSTSSSTSGSSSSS....CTTSHHHHHHHHHHHHHHHHHHHTSCHHHH CS
          PX  59 kiPplPkkvlfgsv....rkkdeefiekrrkgLeeyLqrllnhpelrn 102
                 ++P  P+ +l ++     +++  +   +++++++++ + l++ p++ +
  EEA20610.1 153 IVPAVPSGNLQVTDaepsNRNAGDTSSIQKRDIKSFAELLSHFPMIAR 200
                 566666666555446666666677777777777777776666666554 PP

  == domain 2  score: 27.7 bits;  conditional E-value: 1.3e-09
                  EEEEEEHHHHHHHHHHHHHHHTTSTSTSSSTSGSSSSS.CTTSHHHHHHHHHHHHHHHHHHHTSCHHHHSHHHHHHH CS
          PX   35 wtvkRrYsdFeeLhskLlrkfprvkiPplPkkvlfgsv.rkkdeefiekrrkgLeeyLqrllnhpelrnsevlteFL 110 
                   t++R++ dFe+L + L  ++p++ iP++ +++++ +   k +++++   +  L+++L+ ll+hp +   e+l eF+
  EEA20610.1  945 TTCRRSFADFEHLAKCLAVEHPASYIPSISEARSPFQIhSKPSRAILHDMQGRLDQFLRILLTHPTFATHEMLWEFF 1021
                  6899**************************99977644678899999****************************98 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.2   0.0    0.0049       7.9       8      51 ..     653     701 ..     650     708 .. 0.78
   2 ?   -2.6   0.0       5.5     9e+03      15      39 ..     739     762 ..     728     766 .. 0.66
   3 ?   -0.3   0.0       1.1   1.7e+03      28      42 ..     799     812 ..     786     817 .. 0.87
   4 !    9.5   0.0   0.00091       1.5      19      52 ..     821     853 ..     813     856 .. 0.81

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0049
       Ank_4   8 aaisgrlelvrlLl....ekgad..inaqdnrsGetalhiAakrgnveil 51 
                 a++s +  ++++Ll    ++ +d  +  + nr+G t+l  A+++ n +++
  EEA20610.1 653 AVESHQPAALKYLLslqeYYSIDviLEDT-NRDGTTLLSAAVQHANRKVV 701
                 66677777899999776445777766666.**************997665 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 5.5
       Ank_4  15 elvrlLlekgadinaqdnrsGetal 39 
                 +++++ l +   + ++ ++ G+t+l
  EEA20610.1 739 PYLMSSLGSLLPWQKR-DKHGQTPL 762
                 4556666666678888.88888888 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 1.1
       Ank_4  28 naqdnrsGetalhiA 42 
                 +++ +  G+t+lhi+
  EEA20610.1 799 DHV-DLKGNTLLHIV 812
                 677.889******97 PP

  == domain 4  score: 9.5 bits;  conditional E-value: 0.00091
       Ank_4  19 lLlekgadinaqdnrsGetalhiAakrgnveilk 52 
                 +L e + d+na+ n++ +t+l  A k g+v+  +
  EEA20610.1 821 ILAECDCDPNAT-NERKFTPLMVASKYGRVDLMR 853
                 4444489*****.****************99765 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.1      0.18     3e+02       1      31 [.     684     716 ..     684     717 .. 0.74
   2 ?   -2.3   0.0       4.7   7.7e+03       1      11 [.     757     768 ..     757     776 .. 0.71
   3 !    8.6   0.0    0.0016       2.6       2      31 ..     805     833 ..     804     834 .. 0.85
   4 ?    5.8   0.0     0.012        20       3      20 ..     837     851 ..     835     864 .. 0.77

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.18
                 TSBBHHHHHHHHTT...HHHHHHHHTTTSTTCBT CS
         Ank   1 dGnTPLHlAatngk...kriiklLLhGAnlnald 31 
                 dG T L  A++ ++   ++ii ++L  A+ ++++
  EEA20610.1 684 DGTTLLSAAVQHANrkvVDIITDFL-LAETDIHT 716
                 899*****99666667899999765.25666665 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 4.7
                 TSBBHHHHHH.H CS
         Ank   1 dGnTPLHlAa.t 11 
                 +G TPL   + +
  EEA20610.1 757 HGQTPLFAICrS 768
                 69****864544 PP

  == domain 3  score: 8.6 bits;  conditional E-value: 0.0016
                 SBBHHHHHHHHTTHHHHHHHH..TTTSTTCBT CS
         Ank   2 GnTPLHlAatngkkriiklLL..hGAnlnald 31 
                 GnT LH+ + +    ii  +L  + +++na++
  EEA20610.1 805 GNTLLHIVSDPE---IITRILaeCDCDPNATN 833
                 9******67776...99999987789****98 PP

  == domain 4  score: 5.8 bits;  conditional E-value: 0.012
                 BBHHHHHHHHTTHHHHHH CS
         Ank   3 nTPLHlAatngkkriikl 20 
                 +TPL++A+ +g    + l
  EEA20610.1 837 FTPLMVASKYG---RVDL 851
                 8*******999...6653 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0       3.3   5.3e+03       7      23 ..     651     667 ..     650     676 .. 0.83
   2 ?   -1.0   0.0       2.7   4.4e+03       4      21 ..     687     704 ..     684     715 .. 0.72
   3 ?   -0.0   0.0       1.3   2.1e+03       1      12 [.     757     768 ..     757     772 .. 0.90
   4 ?    2.2   0.0      0.24   3.9e+02       2      30 ..     805     830 ..     804     831 .. 0.62
   5 !    8.3   0.0    0.0026       4.2       4      28 ..     838     862 ..     835     865 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 3.3
       Ank_3   7 hlAarsgnleivkfLle 23 
                 ++A++s  ++ +k+Ll 
  EEA20610.1 651 MMAVESHQPAALKYLLS 667
                 68999999999****98 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 2.7
       Ank_3   4 tpLhlAarsgnleivkfL 21 
                 t+L  A+ ++n ++v+ +
  EEA20610.1 687 TLLSAAVQHANRKVVDII 704
                 99999******9765433 PP

  == domain 3  score: -0.0 bits;  conditional E-value: 1.3
       Ank_3   1 nGetpLhlAars 12 
                 +G+tpL+  +rs
  EEA20610.1 757 HGQTPLFAICRS 768
                 79*****99986 PP

  == domain 4  score: 2.2 bits;  conditional E-value: 0.24
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G+t+Lh++     +   + L e + +d+n
  EEA20610.1 805 GNTLLHIVSDPEII--TRILAE-CDCDPN 830
                 99****66544444..455555.777777 PP

  == domain 5  score: 8.3 bits;  conditional E-value: 0.0026
       Ank_3   4 tpLhlAarsgnleivkfLlenkgad 28 
                 tpL++A ++g++++++ L+  + +d
  EEA20610.1 838 TPLMVASKYGRVDLMRRLFADPRVD 862
                 9****************99866666 PP

>> SRP54  SRP54-type protein, GTPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.0      0.16   2.6e+02      30      56 ..     271     297 ..     264     317 .. 0.82
   2 !   12.7   0.0   4.6e-05     0.075      11      87 ..     628     704 ..     622     707 .. 0.94

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.16
                 S-EEEEEESTSSTTHHHHHHHHHHHTT CS
       SRP54  30 kkvllvaaDtfRaaAveQLktlaeklg 56 
                 ++++ +a D+fR    +QL+ l+ +++
  EEA20610.1 271 ETAVTAAIDIFRLVDKQQLSLLGATTD 297
                 5667899**************998876 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 4.6e-05
                 TSSHHHHHHHHHHHHHHTTS-EEEEEESTSSTTHHHHHHHHHHHTTEEEEESSTTSCHHHHHHHHHHHHHHTTSSEE CS
       SRP54  11 GaGKTttlaKLaallkkegkkvllvaaDtfRaaAveQLktlaeklgvpvikkkeeadpaavakeavekakeekidvv 87 
                 G+   t++  L++     g +v ++a+    +aA++ L  l e + ++vi +++++d  +++++av++a+++ +d++
  EEA20610.1 628 GIEGDTSIETLSHTHDPAGDSVPMMAVESHQPAALKYLLSLQEYYSIDVILEDTNRDGTTLLSAAVQHANRKVVDII 704
                 555579999*****************************************************************987 PP

>> ThiJ_like  ThiJ/PfpI family-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.0    0.0074        12      34      71 ..      21      59 ..      10      66 .. 0.81
   2 ?    5.1   0.0    0.0098        16      12      62 ..     907     956 ..     898     972 .. 0.77

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0074
   ThiJ_like 34 vpkadekllsgikakllgaskeakd.iYkelstleeFke 71
                vp  ++ ll +++ +l+g+  + ++ +Y++l+++eeF  
  EEA20610.1 21 VPVENHVLLVPTTESLFGSRDKDSNvLYSDLVSSEEFLG 59
                899999999*********987666537**********75 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0098
   ThiJ_like  12 aipwkvlkdagfsveFvtekgkvpkadekllsgikakllgaskeakdiYke 62 
                  ++ ++l  ++ +v F+ ++g+ ++ d + ++g++  + +  ++ +d +++
  EEA20610.1 907 TTVVRSLFVEDATVRFILKSGAQASSDTTSVNGTTYAITTCRRSFAD-FEH 956
                 566677888999**********************9999887765544.455 PP

>> BsuBI_PstI_RE_N  BsuBI/PstI restriction endonuclease HTH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   1.2   0.00012       0.2      39      93 ..    1216    1271 ..    1207    1277 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00012
  BsuBI_PstI_RE_N   39 dswaeatdeqalriteimafvkesygkeyaent..rEtiRrqtlhqlvqaglvvens 93  
                       +++ e++ +qa r +  +++ k+ + +e+a  t  rE++ r++++ +v a +v e++
       EEA20610.1 1216 QKINESE-AQASRLSREISWNKDVVVSELAGWTswREKVGRDAIRAFVRATVVQERE 1271
                       3444445.9*********************87777*******************997 PP

>> Flavin_Reduct  Flavin reductase like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       2.1   3.5e+03      55     102 ..     608     651 ..     570     663 .. 0.73
   2 ?   10.8   0.5   0.00023      0.38       4      96 ..    1125    1237 ..    1122    1260 .. 0.78

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 2.1
                    HSEEEEEEEBCCGHHHHHHTCS...SCCCCCCCCC.CCEEECTCCCSEE CS
  Flavin_Reduct  55 agefvinllsesqealadafsqksgprtddksifa.gltweesptgapa 102
                    +g+  i+lls+    +a  fs+     + d+si +   t  ++ + +p+
     EEA20610.1 608 SGSSMISLLSR-TTTIASTFSG----IEGDTSIETlSHTHDPAGDSVPM 651
                    56688999999.5779999999....34444444447777777777776 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00023
                     S-EE-EEEEE.EETTEEEEEEESSEEEEETTTTEEEEEEETT.......SHHHHHHHHHSE...................EEEEEEBCCGHHHH CS
  Flavin_Reduct    4 vaqpvavvttsvpptsplgatlssftslsldPplvafslrlp.......sstadalkeage...................fvinllsesqeala 71  
                     +aq  a  +ts  ++spl   l++ ts++ +   v+ +l +p       s       ++++                   +++++l es ++  
     EEA20610.1 1125 FAQYAAAMSTSSSDSSPLLQFLTTLTSVQSTTTAVLSALSRPgrliytlS-------STNRnlsrsrsslassslprkfnLNLSVLEESRQKNL 1211
                     7888999999999*****9999999999999999******9955555553.......5554555555588888889997788888***999999 PP

                     HHTCS...SCCCCCCCCC.CCEEECT CS
  Flavin_Reduct   72 dafsqksgprtddksifa.gltwees 96  
                     +++ qk  +++ + s ++ +++w ++
     EEA20610.1 1212 RELEQKINESEAQASRLSrEISWNKD 1237
                     99999777666666667667777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1294 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       876  (0.0488594); expected 358.6 (0.02)
Passed bias filter:                      648  (0.0361426); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.85u 0.28s 00:00:01.12 Elapsed: 00:00:00.53
# Mc/sec: 7355.84
//
Query:       EEA20611.1  [L=241]
Description: 37S ribosomal protein S11, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.9e-09   36.1   0.1    1.7e-08   34.8   0.0    1.6  2  Ribosomal_S11   Ribosomal protein S11
  ------ inclusion threshold ------
       0.11   12.7   3.7       0.16   12.1   2.0    1.9  3  CTNNB1_binding  N-terminal CTNNB1 binding


Domain annotation for each model (and alignments):
>> Ribosomal_S11  Ribosomal protein S11
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0       0.7   6.3e+03      35      62 ..      52      79 ..      42     100 .. 0.53
   2 !   34.8   0.0   1.9e-12   1.7e-08       3     110 .]     123     239 ..     122     239 .. 0.86

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.7
  Ribosomal_S11 35 kasrkssPyaaqlaaekaaekvldkGik 62
                   + +r++    + + a++  +++   G+ 
     EEA20611.1 52 RRQRETDVLRSSQSANTESSSSNSSGVA 79
                   4444444444444444444444444444 PP

  == domain 2  score: 34.8 bits;  conditional E-value: 1.9e-12
  Ribosomal_S11   3 ahiqasfnntiititdlkGaevlvksaGglgvkasrkssPyaaqlaaekaaekvldkG....ikavevkvkgpGpGreaalral.araGlk....i 89 
                     h++a   ntiit+t  +G+ +++  +G +g+++s++s    a + ++++  ++ +kG    ik + + ++g G Grea ++ l  + G +    +
     EEA20611.1 123 LHVYAHKHNTIITLTRPNGNPLMSLGCGNIGFRKSHRSGYDPAYQLSSHVFAQIQEKGllheIKGITLVLRGFGMGREAFIKVLlGNEGRNvrplV 218
                    69**********************************9998899999999999999999544468899***************97335565422437 PP

  Ribosomal_S11  90 griedvtPiPhdgirrpkkrr 110
                    +r++d t i   g+r+++ rr
     EEA20611.1 219 TRVTDNTTIKFGGTRSRHVRR 239
                    999999999999999988776 PP

>> CTNNB1_binding  N-terminal CTNNB1 binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0     0.078     7e+02     154     180 ..      33      58 ..      23      62 .. 0.79
   2 ?   12.1   2.0   1.8e-05      0.16      36     110 ..      52     126 ..      42     141 .. 0.77
   3 ?   -1.6   0.0      0.28   2.6e+03     175     197 ..     155     177 ..     149     179 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.078
  CTNNB1_binding 154 fspgshpshlpadidpktgvpRpphts 180
                     fs   +ps++p+d   + +v R+++t 
      EEA20611.1  33 FSTV-SPSYAPPDSARDSAVRRQRETD 58 
                     5555.69999**********9998775 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 1.8e-05
  CTNNB1_binding  36 saerDLadvKSSLVnEsEssssssseeeaerrrkskkdqesyaekardsleelrkqqdgglykks.vysgypflml 110
                       +r+ + ++SS    +E ssss+s+++a+  r  +kd+++  +k+  + + lrk+q+++  + +   + y++ + 
      EEA20611.1  52 RRQRETDVLRSSQSANTE-SSSSNSSGVADILRMMQKDRQVAGQKSATYADGLRKRQEETYQAYGnRAPPYNLHVY 126
                     4678888899*9999999.6678888999****************9999999999998755444335555665554 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 0.28
  CTNNB1_binding 175 RpphtsdlspfYplspggvgqit 197
                     R++h s   p Y ls+   +qi 
      EEA20611.1 155 RKSHRSGYDPAYQLSSHVFAQIQ 177
                     77888889999****99999996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (241 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       647  (0.0360868); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.24s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 1784.69
//
Query:       EEA20612.1  [L=509]
Description: mitochondrial inner membrane translocase subunit TIM44, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-34  118.7   0.0    5.6e-34  117.4   0.0    1.8  1  Tim44     Tim44-like domain
  ------ inclusion threshold ------
       0.14   12.2   4.5       0.33   11.0   4.5    1.6  1  Med7      MED7 protein


Domain annotation for each model (and alignments):
>> Tim44  Tim44-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.4   0.0   6.2e-38   5.6e-34       2     147 .]     350     503 ..     349     503 .. 0.97

  Alignments for each domain:
  == domain 1  score: 117.4 bits;  conditional E-value: 6.2e-38
                 HHHHHHHHHH-TT--HHHHHHHHHHTHHH.HHHHHHHT-HHHHHHHB-HHHHHHHHHHHHHHHHTT-EE--EEEEEEEEEEEEEEEE..TTEEEEEEEE CS
       Tim44   2 asalaaikqrdpsFdkeeFleeakeayep.ileayakgDletLrkllteevyeefkaeikerakqgltldaellgirevdlkeakie..gdtavltvrf 97 
                 a+++++++++dpsF++e Fl+e++e++ p +l+ay+kgD etL+ +l+++ +++++a  +++++ g ++d ++l+ir vd+++a++   gd +v+++++
  EEA20612.1 350 ARVIKKFREMDPSFQLEPFLREMREYILPeVLDAYVKGDIETLKLWLSDAQFSVYSALAQQYTTLGMKSDGRILDIRGVDIANARMLepGDIPVFVITC 448
                 799************************************************************************************9*********** PP

                 EEEEE-E.E-TTS.-EEEE-TT--EEEEEEEEEEE-...-S-G.GG-EEEEEEEE CS
       Tim44  98 rtqqisv.tddatGevveGdedkvvevrevwtfeRd...lgse.dpnWrLveiqa 147
                 rtq+++v ++ +t e+++G ed+v+ v++++ ++R    ++++ +++Wr++e+q+
  EEA20612.1 449 RTQEVHVyRNSKTNELAAGMEDRVQLVTYAIGVTRIpedVNNPeTRGWRMIELQK 503
                 *******999999**********************999988888********985 PP

>> Med7  MED7 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   4.5   3.7e-05      0.33      20      93 ..      80     152 ..      71     181 .. 0.59

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 3.7e-05
        Med7  20 kklkelkeeaekeeeeeedesaaeeqelelpkeLrvlipPeppk..egeYrvFGenwsllkdklpsLeeqgieqly 93 
                 ++  + k+++++e+e+e d+++++e+e e+  e +  +pP+pp   ++ ++vF e+ +  + k  +  e+g + l 
  EEA20612.1  80 EQ--AQKNQKKAEAEPEADSEKKTESEGESSREQKKDVPPPPPHgdKTPWQVFTETLRS-EFKKSKEWEEGTKALA 152
                 22..233333334444444444444444445555555688888656889******9995.5444444444555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (509 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1947  (0.108595); expected 358.6 (0.02)
Passed bias filter:                      799  (0.0445647); expected 358.6 (0.02)
Passed Vit filter:                       105  (0.00585643); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.75u 0.30s 00:00:01.05 Elapsed: 00:00:00.45
# Mc/sec: 3375.63
//
Query:       EEA20613.1  [L=350]
Description: Hsc70 cochaperone (SGT), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    8.8e-24   83.1   0.1    1.4e-23   82.4   0.1    1.4  1  SGTA_dimer   Homodimerisation domain of SGTA
    5.5e-16   57.6   6.7    1.8e-05   24.3   0.2    3.6  3  TPR_1        Tetratricopeptide repeat
    3.1e-14   51.9   8.8    0.00022   21.1   0.2    3.4  3  TPR_2        Tetratricopeptide repeat
    3.3e-11   42.7  10.4    2.4e-06   27.1   1.5    3.3  3  TPR_11       TPR repeat
      1e-09   37.8   6.0     0.0021   18.1   0.2    3.6  3  TPR_8        Tetratricopeptide repeat
      1e-08   35.6  12.5    0.00029   21.4   4.2    2.7  2  TPR_16       Tetratricopeptide repeat
    2.1e-07   30.8   2.3     0.0023   18.2   0.4    3.5  3  TPR_17       Tetratricopeptide repeat
    9.1e-07   29.2   7.0       0.15   13.0   0.5    3.7  3  TPR_14       Tetratricopeptide repeat
    1.3e-06   28.0   0.6       0.34   11.0   0.0    3.5  3  TPR_7        Tetratricopeptide repeat
    2.3e-06   27.8   7.3     0.0011   19.2   1.8    2.7  2  TPR_12       Tetratricopeptide repeat
      1e-05   25.6   2.0    6.7e-05   23.0   1.1    2.2  2  TPR_9        Tetratricopeptide repeat
    1.5e-05   25.4   3.8     0.0018   18.8   0.6    2.4  2  TPR_19       Tetratricopeptide repeat
    5.6e-05   23.0   5.3     0.0026   17.6   2.9    2.4  2  STI1         STI1 domain
     0.0031   17.3  10.2       0.14   12.0   0.5    3.6  3  TPR_10       Tetratricopeptide repeat
     0.0042   17.6   3.7       0.28   11.9   0.2    3.6  3  TPR_6        Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.012   15.3   1.5      0.027   14.2   1.5    1.6  1  XPC-binding  XPC-binding domain
      0.022   15.2   1.1      0.022   15.2   1.1    1.9  2  BTAD         Bacterial transcriptional activator domain
      0.082   13.0   0.7        3.7    7.7   0.1    2.5  2  MIT          MIT (microtubule interacting and transport) doma
       0.25   12.1   1.9         33    5.5   0.6    2.7  2  TPR_4        Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> SGTA_dimer  Homodimerisation domain of SGTA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.4   0.1   1.5e-26   1.4e-23       1      67 []       6      71 ..       6      71 .. 0.95

  Alignments for each domain:
  == domain 1  score: 82.4 bits;  conditional E-value: 1.5e-26
  SGTA_dimer  1 skkrlalaIidFLstslkdgtvseDdaESleVAiqCIaeaFevdkedkaavkkakfggqsLleilev 67
                skkrlalaI+dFL +slkdgt++++da+S+e+A++CIae+F+vd++d+ a ++a  ggqsL +i++v
  EEA20613.1  6 SKKRLALAIVDFLGSSLKDGTLTAEDADSIEIAQNCIAETFGVDPTDSVALQDAL-GGQSLFSIYNV 71
                69**********************************************9998666.*********85 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.3   0.2   1.9e-08   1.8e-05       6      34 .]     110     138 ..     106     138 .. 0.92
   2 !   14.5   0.1   2.4e-05     0.023       3      34 .]     141     172 ..     139     172 .. 0.94
   3 !   20.9   0.4   2.4e-07   0.00023       1      29 [.     173     201 ..     173     205 .. 0.95

  Alignments for each domain:
  == domain 1  score: 24.3 bits;  conditional E-value: 1.9e-08
                 HHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1   6 nlGnayfklgkydeAleyyekALelnPnn 34 
                   Gna +  ++yd A++ y kAL + P+n
  EEA20613.1 110 SEGNAAMGRKEYDAAIDLYTKALAIAPSN 138
                 569************************98 PP

  == domain 2  score: 14.5 bits;  conditional E-value: 2.4e-05
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1   3 alynlGnayfklgkydeAleyyekALelnPnn 34 
                  l n+++ay   g++ +A ++ e A+ ++P++
  EEA20613.1 141 YLSNRAAAYSASGQHTKAAADAELAVNVDPQY 172
                 589***************************86 PP

  == domain 3  score: 20.9 bits;  conditional E-value: 2.4e-07
                 HHHHHHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1   1 akalynlGnayfklgkydeAleyyekALe 29 
                 a+a+ +lG+a ++lg+ + A+e+yek +e
  EEA20613.1 173 ARAWSRLGLARYELGDAKGAVEAYEKGIE 201
                 89************************998 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.1   0.2   2.3e-07   0.00022       7      34 .]     111     138 ..     106     138 .. 0.93
   2 !   14.4   0.1   3.2e-05      0.03       2      33 ..     140     171 ..     139     172 .. 0.94
   3 !   20.3   0.8   4.1e-07   0.00039       1      30 [.     173     202 ..     173     205 .. 0.93

  Alignments for each domain:
  == domain 1  score: 21.1 bits;  conditional E-value: 2.3e-07
       TPR_2   7 lGlayyklgdyeeAleafekAleldPnn 34 
                  G+a++ +++y+ A++++ kAl+++P n
  EEA20613.1 111 EGNAAMGRKEYDAAIDLYTKALAIAPSN 138
                 79************************87 PP

  == domain 2  score: 14.4 bits;  conditional E-value: 3.2e-05
       TPR_2   2 ealynlGlayyklgdyeeAleafekAleldPn 33 
                  +l n++ ay ++g++ +A+++ e A+  dP+
  EEA20613.1 140 IYLSNRAAAYSASGQHTKAAADAELAVNVDPQ 171
                 6899**************************98 PP

  == domain 3  score: 20.3 bits;  conditional E-value: 4.1e-07
       TPR_2   1 aealynlGlayyklgdyeeAleafekAlel 30 
                 a+a+ +lGla y+lgd + A+ea+ek +e 
  EEA20613.1 173 ARAWSRLGLARYELGDAKGAVEAYEKGIEA 202
                 78************************9985 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.1   1.5   2.6e-09   2.4e-06       1      42 []     112     153 ..     112     153 .. 0.92
   2 !   20.4   0.4   3.2e-07    0.0003       3      42 .]     148     187 ..     148     187 .. 0.94
   3 !   10.2   0.5   0.00049      0.46       1      22 [.     180     201 ..     180     203 .. 0.94

  Alignments for each domain:
  == domain 1  score: 27.1 bits;  conditional E-value: 2.6e-09
      TPR_11   1 GdayyeqGkyeeAieaYkkAlkldPdnaeayynLGlayykqG 42 
                 G+a + + +y++Ai  Y kAl++ P+n+  ++n+++ay + G
  EEA20613.1 112 GNAAMGRKEYDAAIDLYTKALAIAPSNPIYLSNRAAAYSASG 153
                 67777789******************************8766 PP

  == domain 2  score: 20.4 bits;  conditional E-value: 3.2e-07
      TPR_11   3 ayyeqGkyeeAieaYkkAlkldPdnaeayynLGlayykqG 42 
                 ay + G+ ++A ++ + A++ dP++a+a++ LGla y++G
  EEA20613.1 148 AYSASGQHTKAAADAELAVNVDPQYARAWSRLGLARYELG 187
                 5778999999999999**********************98 PP

  == domain 3  score: 10.2 bits;  conditional E-value: 0.00049
      TPR_11   1 GdayyeqGkyeeAieaYkkAlk 22 
                 G a ye+G+ ++A+eaY+k ++
  EEA20613.1 180 GLARYELGDAKGAVEAYEKGIE 201
                 8899***************987 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.1    0.0002      0.19       8      34 .]     112     138 ..     111     138 .. 0.90
   2 !    9.2   0.1    0.0016       1.6       6      33 ..     144     171 ..     141     172 .. 0.91
   3 !   18.1   0.2   2.2e-06    0.0021       1      31 [.     173     203 ..     173     205 .. 0.94

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.0002
                 HHHHHHTT-HHHHHHHHHHHHHHHHH. CS
       TPR_8   8 gsiylklgdyeeAkeyyekaleldpdn 34 
                 g++ +  ++y++A+  y kal ++p+n
  EEA20613.1 112 GNAAMGRKEYDAAIDLYTKALAIAPSN 138
                 67788889*****************86 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.0016
                 HHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   6 nlgsiylklgdyeeAkeyyekaleldpd 33 
                 n + +y+  g++ +A +  e a+  dp+
  EEA20613.1 144 NRAAAYSASGQHTKAAADAELAVNVDPQ 171
                 78889**********************8 PP

  == domain 3  score: 18.1 bits;  conditional E-value: 2.2e-06
                 CCHHHHHHHHHHHTT-HHHHHHHHHHHHHHH CS
       TPR_8   1 aeayynlgsiylklgdyeeAkeyyekaleld 31 
                 a+a+ +lg++  +lgd + A+e+yek +e++
  EEA20613.1 173 ARAWSRLGLARYELGDAKGAVEAYEKGIEAE 203
                 79**************************976 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   4.2   3.1e-07   0.00029       3      59 ..     111     164 ..     110     167 .. 0.91
   2 !   19.7   8.9   1.1e-06     0.001       3      59 ..     145     198 ..     143     207 .. 0.91

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 3.1e-07
      TPR_16   3 laraalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyra 59 
                 +++aa+ +++yd+A+ +++ al+ +   P ++  l +++ a+ + g +++Aaa  + 
  EEA20613.1 111 EGNAAMGRKEYDAAIDLYTKALAIA---PSNPIYLSNRAAAYSASGQHTKAAADAEL 164
                 699**********************...99**********************54444 PP

  == domain 2  score: 19.7 bits;  conditional E-value: 1.1e-06
      TPR_16   3 laraalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyra 59 
                 +a a+ ++g+ ++Aaa +e a+  d   P+ a+A+  lg+a++++g+ ++A+++y++
  EEA20613.1 145 RAAAYSASGQHTKAAADAELAVNVD---PQYARAWSRLGLARYELGDAKGAVEAYEK 198
                 788999************9999999...************************99987 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       3.8   3.5e+03       9      17 ..      49      57 ..      38      58 .. 0.78
   2 !   18.2   0.4   2.4e-06    0.0023       1      32 [.     127     158 ..     127     160 .. 0.95
   3 !   10.1   0.0   0.00091      0.86       5      33 ..     165     193 ..     162     194 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 3.8
      TPR_17  9 dPnnadayn 17
                dP++++a++
  EEA20613.1 49 DPTDSVALQ 57
                8***99985 PP

  == domain 2  score: 18.2 bits;  conditional E-value: 2.4e-06
      TPR_17   1 lylkaleldPnnadaynnLAelllknGdlmtA 32 
                 ly+kal++ P+n+  + n+A +++  G++ +A
  EEA20613.1 127 LYTKALAIAPSNPIYLSNRAAAYSASGQHTKA 158
                 7***************************9877 PP

  == domain 3  score: 10.1 bits;  conditional E-value: 0.00091
      TPR_17   5 aleldPnnadaynnLAelllknGdlmtAr 33 
                 a+  dP +a a+  L+ + +++Gd + A+
  EEA20613.1 165 AVNVDPQYARAWSRLGLARYELGDAKGAV 193
                 56789*******************99997 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.1   0.1   0.00064       0.6      10      35 ..     114     139 ..     111     145 .. 0.87
   2 !   12.8   1.7   0.00017      0.16       7      42 ..     145     180 ..     141     183 .. 0.93
   3 !   13.0   0.5   0.00016      0.15       2      31 ..     174     203 ..     173     211 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00064
      TPR_14  10 allalGdpdeAiallrralalaPdda 35 
                 a + + ++d+Ai+l+ +ala aP+++
  EEA20613.1 114 AAMGRKEYDAAIDLYTKALAIAPSNP 139
                 5667889****************997 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 0.00017
      TPR_14   7 laeallalGdpdeAiallrralalaPddaeawllla 42 
                 +a+a+ a+G++ +A+a ++ a+  +P+ a+aw +l+
  EEA20613.1 145 RAAAYSASGQHTKAAADAELAVNVDPQYARAWSRLG 180
                 799*****************************8876 PP

  == domain 3  score: 13.0 bits;  conditional E-value: 0.00016
      TPR_14   2 eallalaeallalGdpdeAiallrralala 31 
                 +a+ +l+ a ++lGd ++A++++++ +++ 
  EEA20613.1 174 RAWSRLGLARYELGDAKGAVEAYEKGIEAE 203
                 79***********************99975 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.0   0.00036      0.34      14      31 ..     120     137 ..     112     140 .. 0.83
   2 ?    4.2   0.0     0.054        51       2      20 ..     142     160 ..     142     171 .. 0.82
   3 !    9.1   0.1    0.0015       1.4       1      29 [.     175     201 ..     175     209 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00036
       TPR_7  14 dyeeAielyeqsLaltkd 31 
                 +y+ Ai+ly+++La++ +
  EEA20613.1 120 EYDAAIDLYTKALAIAPS 137
                 8**********8888755 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.054
       TPR_7   2 LlnLarlysrlGdyeeAie 20 
                 L+n a +ys+ G++ +A+ 
  EEA20613.1 142 LSNRAAAYSASGQHTKAAA 160
                 7899*************97 PP

  == domain 3  score: 9.1 bits;  conditional E-value: 0.0015
       TPR_7   1 aLlnLarlysrlGdyeeAielyeqsLalt 29 
                 a+++L+ ++ +lGd + A+e ye+  +++
  EEA20613.1 175 AWSRLGLARYELGDAKGAVEAYEK--GIE 201
                 6899*******************9..776 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   1.8   1.2e-06    0.0011      10      75 ..     112     169 ..     108     171 .. 0.89
   2 !   14.5   4.4   3.4e-05     0.032       6      73 ..     142     201 ..     140     202 .. 0.89

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 1.2e-06
      TPR_12  10 aavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaia 75 
                 +++ + +++yd A++l+ kal+ia     p +p    +l n + +y+a+g++ +A +  e a++++
  EEA20613.1 112 GNAAMGRKEYDAAIDLYTKALAIA-----PSNPI---YLSNRAAAYSASGQHTKAAADAELAVNVD 169
                 677788999***************.....98877...7*****************99988887765 PP

  == domain 2  score: 14.5 bits;  conditional E-value: 3.4e-05
      TPR_12   6 lnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleeala 73 
                 l+n+aa++ + g++++A +  e a+++      p+   +a++   Lg + ++lg+ + A+e++e+ ++
  EEA20613.1 142 LSNRAAAYSASGQHTKAAADAELAVNVD-----PQ---YARAWSRLGLARYELGDAKGAVEAYEKGIE 201
                 569*********************9998.....86...58888888888889************9876 PP

>> TPR_9  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.7   0.2   0.00022      0.21       4      61 ..     114     171 ..     112     171 .. 0.94
   2 !   23.0   1.1   7.1e-08   6.7e-05       3      57 ..     147     201 ..     145     213 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00022
       TPR_9   4 iaireedweralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalapd 61 
                 +a+ ++++++a+  +   l++aP  p  +  R+ ++  +G+  +A+ad e ++ ++p+
  EEA20613.1 114 AAMGRKEYDAAIDLYTKALAIAPSNPIYLSNRAAAYSASGQHTKAAADAELAVNVDPQ 171
                 688999******************************************9999999985 PP

  == domain 2  score: 23.0 bits;  conditional E-value: 7.1e-08
       TPR_9   3 aiaireedweralavverllllaPddpeerrdRGlllaqlGclsaAladLeayla 57 
                 a++  + ++ +a a +e+ + ++P+ ++ +   Gl++++lG+ ++A+++ e  ++
  EEA20613.1 147 AAYSASGQHTKAAADAELAVNVDPQYARAWSRLGLARYELGDAKGAVEAYEKGIE 201
                 5688999*****************************************9997665 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.6   1.9e-06    0.0018       2      45 ..     116     159 ..     115     160 .. 0.94
   2 !   13.3   0.4   9.6e-05     0.091       3      57 ..     151     205 ..     150     212 .. 0.92

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 1.9e-06
      TPR_19   2 laegdyaeAlalleqalqedpknaearllLAeallalgqldeAe 45 
                 + ++ y++A++l+++al+ +p n+  + + A a+ a+gq ++A 
  EEA20613.1 116 MGRKEYDAAIDLYTKALAIAPSNPIYLSNRAAAYSASGQHTKAA 159
                 78899*************************************96 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 9.6e-05
      TPR_19   3 aegdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpd 57 
                 a+g+++ A+a  e a   dp++a+a+ +L  a ++lg+ + A ++ ++  e++ +
  EEA20613.1 151 ASGQHTKAAADAELAVNVDPQYARAWSRLGLARYELGDAKGAVEAYEKGIEAEGN 205
                 689*****************************************99998888776 PP

>> STI1  STI1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   2.9   2.8e-06    0.0026      12      48 ..     272     308 ..     272     310 .. 0.91
   2 ?    5.1   0.0     0.022        21      12      28 ..     320     336 ..     319     343 .. 0.80

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 2.8e-06
        STI1  12 PetrellsDPefvakleeiqsNPqalqqymsDprimt 48 
                 P++  l+s+P f ++ + ++sNP +l++ ms+pr  +
  EEA20613.1 272 PDLGSLMSNPMFASVAQNLMSNPDMLNNLMSNPRLRQ 308
                 566689****************************876 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.022
        STI1  12 PetrellsDPefvakle 28 
                 P+++ ++sDP++  + +
  EEA20613.1 320 PDMSSIMSDPSLAEMAK 336
                 88999999999888755 PP

>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.3   0.2    0.0093       8.8       9      31 ..     112     134 ..     112     135 .. 0.91
   2 !   12.0   0.5   0.00015      0.14       5      30 ..     142     167 ..     141     168 .. 0.93
   3 ?    3.7   0.3     0.063        60       7      30 ..     178     201 ..     173     202 .. 0.88

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0093
      TPR_10   9 analrqrgrydeAealleealai 31 
                 +na   r++yd+A +l+ +alai
  EEA20613.1 112 GNAAMGRKEYDAAIDLYTKALAI 134
                 678889***************98 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 0.00015
      TPR_10   5 lnNLanalrqrgrydeAealleeala 30 
                 l+N a+a+++ g++++A a++e a++
  EEA20613.1 142 LSNRAAAYSASGQHTKAAADAELAVN 167
                 89********************9997 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.063
      TPR_10   7 NLanalrqrgrydeAealleeala 30 
                  L+ a +++g+ ++A++ +e+ ++
  EEA20613.1 178 RLGLARYELGDAKGAVEAYEKGIE 201
                 699999**************9776 PP

>> TPR_6  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0       0.1        94      14      32 ..     119     137 ..     110     138 .. 0.82
   2 ?   -0.2   0.1       2.2   2.1e+03       6      24 ..     145     163 ..     142     171 .. 0.71
   3 !   11.9   0.2   0.00029      0.28       5      25 ..     178     198 ..     174     199 .. 0.92

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.1
                 HHHHHHHHHHHHHHHH-TT CS
       TPR_6  14 gdtdkAlealerlikeYPd 32 
                 +++d+A++++ + +   P 
  EEA20613.1 119 KEYDAAIDLYTKALAIAPS 137
                 699*********9998885 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 2.2
                 HHHHHHHHHHHHHHHHHHH CS
       TPR_6   6 lalsyrklgdtdkAleale 24 
                 +a +y + g+++kA +  e
  EEA20613.1 145 RAAAYSASGQHTKAAADAE 163
                 5778888679999987666 PP

  == domain 3  score: 11.9 bits;  conditional E-value: 0.00029
                 HHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   5 klalsyrklgdtdkAlealer 25 
                 +l+l++++lgd+  A+ea+e+
  EEA20613.1 178 RLGLARYELGDAKGAVEAYEK 198
                 89******9**********97 PP

>> XPC-binding  XPC-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   1.5   2.9e-05     0.027       1      29 [.     274     302 ..     274     311 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 2.9e-05
  XPC-binding   1 LefLrnnpqFqqlRqlvqqnPqlLqplLq 29 
                  L +L++np+F+ + q + +nP +L  l+ 
   EEA20613.1 274 LGSLMSNPMFASVAQNLMSNPDMLNNLMS 302
                  678***********************995 PP

>> BTAD  Bacterial transcriptional activator domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       4.4   4.1e+03       9      34 ..     108     133 ..     104     136 .. 0.61
   2 ?   15.2   1.1   2.3e-05     0.022      66     121 ..     143     198 ..     140     202 .. 0.94

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 4.4
                 HHHHHHHHHHTT-HHHHHHHHHHHHT CS
        BTAD   9 lvaagraalaagdpeeaaelleaAla 34 
                 l+++g+aa  + + ++a++l+ +Ala
  EEA20613.1 108 LKSEGNAAMGRKEYDAAIDLYTKALA 133
                 45556666666666666666666665 PP

  == domain 2  score: 15.2 bits;  conditional E-value: 2.3e-05
                 HHHHHHHHHTT-HHHHHHHHHHHHHHSTT-HHHHHHHHHHHHHTT-HHHHHHHHHH CS
        BTAD  66 ealaeaelrlGraeealaelealvaehPlrErlhrqlmrAlarsGrqaeALevYer 121
                   +a+a ++ G++ +a+a++e +v+ +P   r++  l +A + +G+   A e+Ye+
  EEA20613.1 143 SNRAAAYSASGQHTKAAADAELAVNVDPQYARAWSRLGLARYELGDAKGAVEAYEK 198
                 57899999**********************************************97 PP

>> MIT  MIT (microtubule interacting and transport) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.1     0.004       3.7      18      31 ..     119     132 ..     117     134 .. 0.90
   2 ?    3.1   0.0      0.11     1e+02      18      32 ..     187     201 ..     184     225 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.004
         MIT  18 gnyeeAlelYkeal 31 
                 ++y++A++lY++al
  EEA20613.1 119 KEYDAAIDLYTKAL 132
                 89***********8 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.11
         MIT  18 gnyeeAlelYkeale 32 
                 g+ + A+e+Y++++e
  EEA20613.1 187 GDAKGAVEAYEKGIE 201
                 78899********98 PP

>> TPR_4  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.0     0.046        44       3      22 ..     141     160 ..     139     160 .. 0.89
   2 ?    5.5   0.6     0.035        33       1      25 [.     173     197 ..     173     198 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.046
       TPR_4   3 allaLArallalGdldeAra 22 
                  l+++A a+ a G++  A+a
  EEA20613.1 141 YLSNRAAAYSASGQHTKAAA 160
                 589************99986 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.035
       TPR_4   1 arallaLArallalGdldeAralle 25 
                 ara + L+ a ++lGd+  A ++ e
  EEA20613.1 173 ARAWSRLGLARYELGDAKGAVEAYE 197
                 689999**************99877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (350 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       450  (0.025099); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              19  [number of targets reported over threshold]
# CPU time: 0.50u 0.24s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2509.64
//
Query:       EEA20614.1  [L=1081]
Description: DUF1339 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.2e-85  284.2   0.1    1.2e-84  283.6   0.1    1.3  1  RIC1      RIC1
  ------ inclusion threshold ------
       0.12   12.4   0.0       0.48   10.5   0.0    1.9  2  AID       Activation induced deaminase


Domain annotation for each model (and alignments):
>> RIC1  RIC1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  283.6   0.1   1.4e-88   1.2e-84       1     252 []     729     980 ..     729     980 .. 0.94

  Alignments for each domain:
  == domain 1  score: 283.6 bits;  conditional E-value: 1.4e-88
        RIC1   1 lenslwlfdgedikvwldlleiesadeskkesleesvripldfypLsvlldkgiilGvesevslrrslsfalfrletktqlfLhhvLrqlLernlleeA 99 
                 l++slw+f+g+d+  w d++ei ++++     +++ +++p+dfypLsvll+kgiilGvese+ +rr+++f++++ +++t+lfL+++L++ L++ ++ +A
  EEA20614.1 729 LRDSLWMFCGRDLVAWSDVQEILQRED-----VPKPLPVPVDFYPLSVLLNKGIILGVESEMIQRRDITFSILKYAIRTHLFLPYFLQHSLASVDMPSA 822
                 79*****************99988643.....8899*************************************************************** PP

        RIC1 100 lelassyqklsyFahaLElLLhevLeeeadakepsdaseeeealLpavvefl.defpe..yldvvvqCaRKtevarWrtLfdvlgsPkeLFeeclelek 195
                 l+l+++y++lsyF+haLE+LLh+vL++ +d  ++    +e+  lLp+v++fl  + p   yld+vvqC+RK e+++WrtLf++l++Pk+LFe++l+l++
  EEA20614.1 823 LSLSHYYSHLSYFPHALEILLHHVLDDAVDGPNR----DESLPLLPSVISFLqASLPAdvYLDIVVQCTRKNEIRSWRTLFAHLPPPKDLFEQALKLRS 917
                 ******************************9877....579***********77788556*************************************** PP

        RIC1 196 lktAasyLlvLqnleel..eess......qdavrLLklaleekdwelckdLlRFlaaidesgeal 252
                 lktAa+yLlvLq+l+++  e         + avrLL la++++dw+lc +L+RFl a+d sge+l
  EEA20614.1 918 LKTAAGYLLVLQALDDEdeE--TskarteDSAVRLLGLAAHKSDWDLCAELARFLIALDGSGEML 980
                 **************999642..33466779******************************99975 PP

>> AID  Activation induced deaminase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0      0.58   5.2e+03      47      68 ..      88     109 ..      83     115 .. 0.83
   2 ?   10.5   0.0   5.3e-05      0.48      24      80 ..     253     308 ..     244     316 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.58
         AID  47 lkptiyiGrisrsadsdddkal 68 
                  kpt+ +  ++rs  s ++ ++
  EEA20614.1  88 TKPTVVVATVARSQTSLKAYGP 109
                 79************99887665 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 5.3e-05
         AID  24 lwiknsPchecsevllklfkrlplkptiyiGrisrsadsdddkaliellkngFnikv 80 
                 +wi++       +++++ +++    ++++ G+  +   sd+dka++  ++  F + +
  EEA20614.1 253 IWITSDGHAYTVQRKTDAPETEQ-SAKLFKGHCFHTPTSDNDKAIKAAVNARFSLLA 308
                 799999999999*******6665.**********************99999998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1081 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       442  (0.0246528); expected 358.6 (0.02)
Passed bias filter:                      408  (0.0227564); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.72u 0.28s 00:00:01.00 Elapsed: 00:00:00.44
# Mc/sec: 7338.20
//
Query:       EEA20615.1  [L=181]
Description: PUA RNA binding domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-23   82.1   0.1    4.5e-23   81.7   0.1    1.2  1  Pre-PUA   Pre-PUA-like domain
    8.1e-14   51.3   0.3    1.1e-13   50.9   0.3    1.2  1  PUA       PUA domain


Domain annotation for each model (and alignments):
>> Pre-PUA  Pre-PUA-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.7   0.1     5e-27   4.5e-23       1      87 []       2      86 ..       2      86 .. 0.99

  Alignments for each domain:
  == domain 1  score: 81.7 bits;  conditional E-value: 5e-27
     Pre-PUA  1 fkkkfkvksntqlksSdrrkLraklleqfpslseeqleellpkkeevkvvklqgehvelyvvdgeplffqdregellPtlytlwkyP 87
                fkk+f+ +s++++ksS++r+Lr+kl+e++p + e++++e++pkk++++ vkl  ++++ly++d+ plf+q+ +g+ +P+l++++ +P
  EEA20615.1  2 FKKDFQPGSRSKVKSSVQRGLRSKLIETYPGF-EPYIDEIMPKKASLEAVKLP-DRTTLYTIDSTPLFYQPFDGPPIPHLKLIHSFP 86
                9*******************************.********************.********************************9 PP

>> PUA  PUA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.9   0.3   1.3e-17   1.1e-13       1      72 [.      90     169 ..      90     171 .. 0.91

  Alignments for each domain:
  == domain 1  score: 50.9 bits;  conditional E-value: 1.3e-17
                 CEEEE-HHHHHHHHTT-EEEGGGEEEEETT-.......-TTSEEEEEETT.SCEEEEEEESS-HHHHHHHCTSEEEEEEE CS
         PUA   1 grvvvddgAvkallsgasLlapGvvevegdf.......eegdvVaivded.gelvavGlanysseelakikggksveier 72 
                 +++++d+gA++++lsga L+apG+++++g +        +gdvVa+ +e+ +e++ vG  ++ +ee+++  +g++ +  +
  EEA20615.1  90 PKIQIDRGAIRFVLSGAALMAPGLTSAGGRLpdkehalAAGDVVAVSAEGkEEVCLVGPLKMGTEEMKEKGKGVVMDAGH 169
                 69***********************************************84677779************99998776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       237  (0.0132188); expected 358.6 (0.02)
Passed bias filter:                      227  (0.0126611); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.41u 0.24s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1348.63
//
Query:       EEA20616.1  [L=181]
Description: PUA RNA binding domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-23   82.1   0.1    4.5e-23   81.7   0.1    1.2  1  Pre-PUA   Pre-PUA-like domain
    8.1e-14   51.3   0.3    1.1e-13   50.9   0.3    1.2  1  PUA       PUA domain


Domain annotation for each model (and alignments):
>> Pre-PUA  Pre-PUA-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.7   0.1     5e-27   4.5e-23       1      87 []       2      86 ..       2      86 .. 0.99

  Alignments for each domain:
  == domain 1  score: 81.7 bits;  conditional E-value: 5e-27
     Pre-PUA  1 fkkkfkvksntqlksSdrrkLraklleqfpslseeqleellpkkeevkvvklqgehvelyvvdgeplffqdregellPtlytlwkyP 87
                fkk+f+ +s++++ksS++r+Lr+kl+e++p + e++++e++pkk++++ vkl  ++++ly++d+ plf+q+ +g+ +P+l++++ +P
  EEA20616.1  2 FKKDFQPGSRSKVKSSVQRGLRSKLIETYPGF-EPYIDEIMPKKASLEAVKLP-DRTTLYTIDSTPLFYQPFDGPPIPHLKLIHSFP 86
                9*******************************.********************.********************************9 PP

>> PUA  PUA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.9   0.3   1.3e-17   1.1e-13       1      72 [.      90     169 ..      90     171 .. 0.91

  Alignments for each domain:
  == domain 1  score: 50.9 bits;  conditional E-value: 1.3e-17
                 CEEEE-HHHHHHHHTT-EEEGGGEEEEETT-.......-TTSEEEEEETT.SCEEEEEEESS-HHHHHHHCTSEEEEEEE CS
         PUA   1 grvvvddgAvkallsgasLlapGvvevegdf.......eegdvVaivded.gelvavGlanysseelakikggksveier 72 
                 +++++d+gA++++lsga L+apG+++++g +        +gdvVa+ +e+ +e++ vG  ++ +ee+++  +g++ +  +
  EEA20616.1  90 PKIQIDRGAIRFVLSGAALMAPGLTSAGGRLpdkehalAAGDVVAVSAEGkEEVCLVGPLKMGTEEMKEKGKGVVMDAGH 169
                 69***********************************************84677779************99998776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       237  (0.0132188); expected 358.6 (0.02)
Passed bias filter:                      227  (0.0126611); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.38u 0.25s 00:00:00.63 Elapsed: 00:00:00.41
# Mc/sec: 1335.36
//
Query:       EEA20617.1  [L=181]
Description: PUA RNA binding domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-23   82.1   0.1    4.5e-23   81.7   0.1    1.2  1  Pre-PUA   Pre-PUA-like domain
    8.1e-14   51.3   0.3    1.1e-13   50.9   0.3    1.2  1  PUA       PUA domain


Domain annotation for each model (and alignments):
>> Pre-PUA  Pre-PUA-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.7   0.1     5e-27   4.5e-23       1      87 []       2      86 ..       2      86 .. 0.99

  Alignments for each domain:
  == domain 1  score: 81.7 bits;  conditional E-value: 5e-27
     Pre-PUA  1 fkkkfkvksntqlksSdrrkLraklleqfpslseeqleellpkkeevkvvklqgehvelyvvdgeplffqdregellPtlytlwkyP 87
                fkk+f+ +s++++ksS++r+Lr+kl+e++p + e++++e++pkk++++ vkl  ++++ly++d+ plf+q+ +g+ +P+l++++ +P
  EEA20617.1  2 FKKDFQPGSRSKVKSSVQRGLRSKLIETYPGF-EPYIDEIMPKKASLEAVKLP-DRTTLYTIDSTPLFYQPFDGPPIPHLKLIHSFP 86
                9*******************************.********************.********************************9 PP

>> PUA  PUA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.9   0.3   1.3e-17   1.1e-13       1      72 [.      90     169 ..      90     171 .. 0.91

  Alignments for each domain:
  == domain 1  score: 50.9 bits;  conditional E-value: 1.3e-17
                 CEEEE-HHHHHHHHTT-EEEGGGEEEEETT-.......-TTSEEEEEETT.SCEEEEEEESS-HHHHHHHCTSEEEEEEE CS
         PUA   1 grvvvddgAvkallsgasLlapGvvevegdf.......eegdvVaivded.gelvavGlanysseelakikggksveier 72 
                 +++++d+gA++++lsga L+apG+++++g +        +gdvVa+ +e+ +e++ vG  ++ +ee+++  +g++ +  +
  EEA20617.1  90 PKIQIDRGAIRFVLSGAALMAPGLTSAGGRLpdkehalAAGDVVAVSAEGkEEVCLVGPLKMGTEEMKEKGKGVVMDAGH 169
                 69***********************************************84677779************99998776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       237  (0.0132188); expected 358.6 (0.02)
Passed bias filter:                      227  (0.0126611); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.24s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1310.20
//
Query:       EEA20618.1  [L=141]
Description: PUA RNA binding domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.6e-14   52.1   0.3    5.9e-14   51.8   0.3    1.2  1  PUA       PUA domain
    5.1e-08   33.5   0.3    7.2e-08   33.0   0.3    1.2  1  Pre-PUA   Pre-PUA-like domain


Domain annotation for each model (and alignments):
>> PUA  PUA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.8   0.3   6.6e-18   5.9e-14       1      72 [.      50     129 ..      50     131 .. 0.91

  Alignments for each domain:
  == domain 1  score: 51.8 bits;  conditional E-value: 6.6e-18
                 CEEEE-HHHHHHHHTT-EEEGGGEEEEETT-.......-TTSEEEEEETT.SCEEEEEEESS-HHHHHHHCTSEEEEEEE CS
         PUA   1 grvvvddgAvkallsgasLlapGvvevegdf.......eegdvVaivded.gelvavGlanysseelakikggksveier 72 
                 +++++d+gA++++lsga L+apG+++++g +        +gdvVa+ +e+ +e++ vG  ++ +ee+++  +g++ +  +
  EEA20618.1  50 PKIQIDRGAIRFVLSGAALMAPGLTSAGGRLpdkehalAAGDVVAVSAEGkEEVCLVGPLKMGTEEMKEKGKGVVMDAGH 129
                 69***********************************************84677779************99998776655 PP

>> Pre-PUA  Pre-PUA-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.0   0.3     8e-12   7.2e-08      41      87 .]       1      46 [.       1      46 [. 0.99

  Alignments for each domain:
  == domain 1  score: 33.0 bits;  conditional E-value: 8e-12
     Pre-PUA 41 lpkkeevkvvklqgehvelyvvdgeplffqdregellPtlytlwkyP 87
                +pkk++++ vkl  ++++ly++d+ plf+q+ +g+ +P+l++++ +P
  EEA20618.1  1 MPKKASLEAVKLP-DRTTLYTIDSTPLFYQPFDGPPIPHLKLIHSFP 46
                79***********.********************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (141 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       217  (0.0121033); expected 358.6 (0.02)
Passed bias filter:                      210  (0.0117129); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.28s 00:00:00.70 Elapsed: 00:00:00.46
# Mc/sec: 925.54
//
Query:       EEA20619.1  [L=394]
Description: GTP-binding protein YchF [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.7e-36  122.6   0.1    1.5e-35  121.3   0.1    1.7  1  YchF-GTPase_C  Protein of unknown function (DUF933)
      2e-16   60.1   0.0    5.5e-16   58.7   0.0    1.9  1  MMR_HSR1       50S ribosome-binding GTPase
    0.00066   19.7   0.0     0.0018   18.3   0.0    1.8  1  TGS            TGS domain
    0.00094   18.7   0.0     0.0019   17.8   0.0    1.5  1  FeoB_N         Ferrous iron transport protein B
  ------ inclusion threshold ------
        6.5    7.2   7.0    1.6e+02    2.6   7.0    2.4  1  AAA_23         AAA domain


Domain annotation for each model (and alignments):
>> YchF-GTPase_C  Protein of unknown function (DUF933)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.3   0.1   4.1e-39   1.5e-35       1      82 [.     307     388 ..     307     390 .. 0.98

  Alignments for each domain:
  == domain 1  score: 121.3 bits;  conditional E-value: 4.1e-39
  YchF-GTPase_C   1 LitffTaGekevraWtikkgttapqaAgviHsDfekgFiraevikyedlvelgseaaakeagklrlegkdyvvqdgDiilfk 82 
                    L +ffT+G++evr+Wti+kgt+apqaAgviH+Dfek+Fi+a v++y+ l+elg eaa+k+agk+ ++gk+yvv+dgDi+l+k
     EEA20619.1 307 LGSFFTCGSDEVRQWTIRKGTKAPQAAGVIHTDFEKTFIQAIVFNYNTLKELGDEAAVKAAGKVMTKGKEYVVEDGDILLIK 388
                    679****************************************************************************998 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.7   0.0   1.5e-19   5.5e-16       3      87 ..      24     135 ..      22     263 .. 0.85

  Alignments for each domain:
  == domain 1  score: 58.7 bits;  conditional E-value: 1.5e-19
                 EEEESTTSSHHHHHHHHHTS.TEEESSSTTSSSSEEEEEEEETTEE.................EEEEECGGCSSHHHHHHHHHHHHHHHHC.TSEEEEE CS
    MMR_HSR1   3 aivGrpNvGKStLinaltge.kaivsdkpgtTrdinegrvklkgke.................ielvDtpGliegaseekglgkaflalee.adlillv 82 
                 +ivG  NvGKStL++a+t+      +++p +T+d++e+rv + + +                 ++++D++Gl  gas++ glg+afl++++ +d+i+ v
  EEA20619.1  24 GIVGLANVGKSTLFQAITKCsLGNPANFPYATIDPEEARVIVPDARydwlceqykpksrvpanLTVYDIAGLTRGASTGAGLGNAFLSHIRaVDAIFQV 122
                 8******************758899**************994432244555555555666666********888*****************55****** PP

                 EETT........T CS
    MMR_HSR1  83 vdas........e 87 
                 v++         e
  EEA20619.1 123 VRCFddaeiihvE 135
                 *988654444442 PP

>> TGS  TGS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   5.1e-07    0.0018      12      58 ..     322     387 ..     300     389 .. 0.92

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 5.1e-07
                 EEETTB-HHHHHHHHSTTHHHHEEEEEECS...................EEEETTSBB-SSEEEEE CS
         TGS  12 dlprgatveDfAykIhrslakkfiyAlVnG...................qrvgldhvLedgdvveI 58 
                 ++++g+ + ++A  Ih+++ k+fi A+V                     +  g ++v+edgd++ I
  EEA20619.1 322 TIRKGTKAPQAAGVIHTDFEKTFIQAIVFNyntlkelgdeaavkaagkvMTKGKEYVVEDGDILLI 387
                 389999999******************************************************988 PP

>> FeoB_N  Ferrous iron transport protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   5.2e-07    0.0019       5      43 ..      25      64 ..      21      72 .. 0.85

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 5.2e-07
                EEESTTSSHHHHHHHHHTTSE.EEEESTTSSSEEEEEEEE CS
      FeoB_N  5 lvGnpnvGkttlfnaltgakq.kvgNwpGvtvekkegklk 43
                +vG  nvGk+tlf a+t+ +  + +N+p  t++ +e+++ 
  EEA20619.1 25 IVGLANVGKSTLFQAITKCSLgNPANFPYATIDPEEARVI 64
                89****************9853789********9998875 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   7.0     0.046   1.6e+02      24      52 ..      25      53 ..      11     288 .. 0.70

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.046
      AAA_23 24 ItGpNGaGKTTildAiklaLygetprlsr 52
                I+G    GK+T+++Ai+ +  g +++++ 
  EEA20619.1 25 IVGLANVGKSTLFQAITKCSLGNPANFPY 53
                7888889*********9998887666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (394 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       728  (0.0406046); expected 358.6 (0.02)
Passed bias filter:                      576  (0.0321267); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.58u 0.31s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 2498.78
//
Query:       EEA20620.1  [L=687]
Description: dynamin family GTPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.1e-18   67.9   0.7    5.3e-18   65.6   0.1    2.3  3  Dynamin_N  Dynamin family
    1.5e-12   47.4   0.4    4.6e-11   42.5   0.1    2.7  2  Dynamin_M  Dynamin central region
    1.6e-06   28.1   0.0    7.5e-06   26.0   0.0    2.1  1  MMR_HSR1   50S ribosome-binding GTPase
    0.00045   19.8   0.0     0.0036   16.8   0.0    2.1  2  FeoB_N     Ferrous iron transport protein B
  ------ inclusion threshold ------
      0.079   13.4   0.0       0.44   11.0   0.0    2.2  2  CDT1_C     DNA replication factor Cdt1 C-terminal domain


Domain annotation for each model (and alignments):
>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.6   0.1   1.5e-21   5.3e-18       9     167 ..      47     226 ..      45     227 .. 0.87
   2 ?   -1.1   0.1      0.48   1.7e+03      42      96 ..     274     329 ..     260     387 .. 0.80
   3 ?   -2.8   0.0       1.5   5.6e+03     108     137 ..     449     478 ..     407     487 .. 0.82

  Alignments for each domain:
  == domain 1  score: 65.6 bits;  conditional E-value: 1.5e-21
                 TTHHHHHHHHHTS--S---SSS---S-EEEEECCT---C...............CS...SSEEEE..T-EB--CHHHHHHHHHHHHHHHTSSSS--SS. CS
   Dynamin_N   9 sGKSSvlnaLlgedilprgpnptTrrplelqlgeeeeas...............eravkeelkek..ekkledfsevreeieketekiagankgiskk. 89 
                  GKSSvl a+++   +p+++ ++Tr p++++ ++++ as               +++ +e+ k++  ++ +  +s +++ i+++t++i g   + +++ 
  EEA20620.1  47 TGKSSVLQAITEIS-FPVESALCTRFPIKISFRQTPGAStsvqaeiipgkttqyDEELIERTKDFrfTSSELTISVMADIIQEATDRIFGDEGKADQTl 144
                 7*************.7****************99999888999999998877777777778888899999999999***********997444443335 PP

                 ...-EEEEEEETTS-SEEEEE---B-S.SSGTTSHHHHHHH.STTEEEEEEEETTS-CCC-CHHHHHHHHSTTBTTEEEEEE- CS
   Dynamin_N  90 ...villkilsllvkgltlvDlPGlds.vnkrdqelvkeyi.kkadiilavtsanhdlsnsealflarevdpkgkrtivvltk 167
                    ++ ++  ++++ + t+vDlPG    ++k  ++lv++++ ++++i+l+v++ ++d+ + ++l+l +e+   ++rti+vltk
  EEA20620.1 145 sdaILRIERSGPNEMHWTIVDLPGNPTdNAKIAKDLVRSFLeNERNIVLWVVD-DTDIERHKSLELFEEIPGLQSRTIGVLTK 226
                 66699*******************8662556666*******999999999998.578*************************9 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.48
                 CT---CCS...SSEEEET-EB--CHHHHHHHHHH.HHHHHTSSSS--SS-EEEEEE CS
   Dynamin_N  42 eeeeaseravkeelkekekkledfsevreeieke.tekiagankgiskkvillkil 96 
                 +++++s+ ++k e+ + +k ++ ++ + ++i+k+ +++i++++ +i k++  lk+l
  EEA20620.1 274 RDQNESDLFEKPEWASVRKSQTGIKVLMDHIDKArRSRIQESMPKIIKEIRELKKL 329
                 45555677788888888999999998888887751456777888888886666654 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 1.5
                 ---B-SSSGTTSHHHHHHH.STTEEEEEEEE CS
   Dynamin_N 108 lPGldsvnkrdqelvkeyi.kkadiilavts 137
                 lPG +s ++++ ++ +e+  + +di + +++
  EEA20620.1 449 LPGTISPEVEE-KIFREQSaHWRDIAFDLVN 478
                 79999999998.6666555588888776655 PP

>> Dynamin_M  Dynamin central region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.5   0.1   1.3e-14   4.6e-11      10     220 ..     250     486 ..     238     496 .. 0.77
   2 ?   -3.1   0.0         1   3.6e+03     137     150 ..     585     598 ..     546     635 .. 0.49

  Alignments for each domain:
  == domain 1  score: 42.5 bits;  conditional E-value: 1.3e-14
   Dynamin_M  10 ipLklGYvgVvnRsqkdInkkksieealkkEkaFFeshpayrkl.adkaGtpyLakkLnqiLvehIrkslPelkkkineklqklekeleelgeskpsde 107
                  +L +G++g +nR  k+  ++ s +e+ ++E+++Fe+ ++  ++ ++++G+++L   + +   + I++s+P++ k+i+        el++lge+ ++ +
  EEA20620.1 250 NHLDQGWFGLRNRKPKE--AHISDQERDQNESDLFEKPEW-ASVrKSQTGIKVLMDHIDKARRSRIQESMPKIIKEIR--------ELKKLGEKGDTPA 337
                 589**********9999..799*************99755.7777*******************************97........8999998665555 PP

   Dynamin_M 108 ektklllqlitkfkedfkklieGe.se..vstkelsggarire...iFnetlekslekidpleelsd...............................e 169
                  ++++ +q ++  ++   ++++G+ ++  +++ ++ +  r+++   iF++t++   + i+p  ++                                 +
  EEA20620.1 338 AQRSYAMQFCNYLQKMADSALRGRyQDipLNNPNVMLRFRVNQrldIFQKTMAD-GDGIEPNLRFHLiedalqylaesgvspeywvefiahndgadlyS 435
                 9***********************533332333333334444311145553331.22222222222233344455556666677777777777777889 PP

   Dynamin_M 170 eirtairnsrGrelplfvpekaFealvkkqikkleepalkcvelVyeelek 220
                  i +  + +rG++lp+ +++++ e+++++q + ++++a ++v+ +++ +++
  EEA20620.1 436 RIYNESKVCRGTNLPGTISPEVEEKIFREQSAHWRDIAFDLVNDIKTLVKE 486
                 9*****************************************888776655 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 1
   Dynamin_M 137 kelsggarireiFn 150
                  + ++  ++++iF+
  EEA20620.1 585 GQAHISLEMNQIFH 598
                 22333333344444 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0   0.0   2.1e-09   7.5e-06       9      95 ..      46     205 ..      44     226 .. 0.71

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 2.1e-09
                 TSSHHHHHHHHHTSTEEESSSTTSSSSEEEEEEEETTEE............................................................ CS
    MMR_HSR1   9 NvGKStLinaltgekaivsdkpgtTrdinegrvklkgke............................................................ 47 
                 N+GKS++++a+t+    v + + +Tr ++++ ++  +++                                                            
  EEA20620.1  46 NTGKSSVLQAITEISFPV-ESALCTRFPIKISFR--QTPgastsvqaeiipgkttqydeeliertkdfrftsseltisvmadiiqeatdrifgdegkad 141
                 9***********833333.334455555555554..11122334444444444455666666666678899999999999999999999999999**** PP

                 ...................EEEEECGGCSS.HHHHHHHHHHHHHHHHCTSEEEEEEETTTTCSHHHHH CS
    MMR_HSR1  48 ...................ielvDtpGlie.gaseekglgkaflaleeadlillvvdaseeklkplde 95 
                                    +++vD+pG    +a+  k+l ++fl++e+ +++l+vvd + + +++  +
  EEA20620.1 142 qtlsdailriersgpnemhWTIVDLPGNPTdNAKIAKDLVRSFLENER-NIVLWVVDDT-D-IERH-K 205
                 ***************************5546889999********999.********44.3.4332.2 PP

>> FeoB_N  Ferrous iron transport protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0      0.18   6.3e+02      10      24 ..      46      60 ..      44      64 .. 0.86
   2 !   16.8   0.0     1e-06    0.0036      46     129 ..     158     241 ..     149     246 .. 0.80

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.18
                TSSHHHHHHHHHTTS CS
      FeoB_N 10 nvGkttlfnaltgak 24
                n+Gk++++ a+t+ +
  EEA20620.1 46 NTGKSSVLQAITEIS 60
                9**********9865 PP

  == domain 2  score: 16.8 bits;  conditional E-value: 1e-06
                 TEEEEEEE----SSSSSSSHHHHHHHHHHHCTSSSEEEEEEEGGGHHHH..HHHHHHHHHTTSSEEEEEETHHHHHHTTEEE-HHH CS
      FeoB_N  46 gkeveivDlPGiYslsayseeekvardflleeepdvvvnvvdatnlern..LyLtlqllelgvpvvlalnmideaekkgieidlkk 129
                 + + +ivDlPG  + ++  + + ++r+fl + e ++v+ vvd t +er+  L L+ ++  l+ +++ +l ++d  +++  +  +k 
  EEA20620.1 158 EMHWTIVDLPGNPT-DNAKIAKDLVRSFLEN-ERNIVLWVVDDTDIERHksLELFEEIPGLQSRTIGVLTKCDRKQETSDNWMVKL 241
                 56789******854.5566777788888865.569************85449999******************9988776655555 PP

>> CDT1_C  DNA replication factor Cdt1 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0      0.99   3.6e+03      35      71 ..     120     160 ..     100     191 .. 0.78
   2 ?   11.0   0.0   0.00012      0.44      23      66 ..     305     357 ..     285     423 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.99
      CDT1_C  35 pdvarilrllf....vaekksalpmeevvkklkdSlrtpvs 71 
                 + +a+i++         e k   ++++++ +++ S ++ + 
  EEA20620.1 120 SVMADIIQEATdrifGDEGKADQTLSDAILRIERSGPNEMH 160
                 55666666554444488899999999999999999988875 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 0.00012
      CDT1_C  23 elerrsallgrlpdvarilrllf.........vaekksalpmeevvkklkdSl 66 
                 ++ rrs   + +p++++ +r l           a++  a+++++ ++k++dS 
  EEA20620.1 305 DKARRSRIQESMPKIIKEIRELKklgekgdtpAAQRSYAMQFCNYLQKMADSA 357
                 678899999**********************9999****************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (687 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       534  (0.0297841); expected 358.6 (0.02)
Passed bias filter:                      402  (0.0224218); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.66u 0.31s 00:00:00.97 Elapsed: 00:00:00.46
# Mc/sec: 4444.62
//
Query:       EEA20621.1  [L=325]
Description: epoxide hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.8e-14   54.0   0.2    2.7e-14   53.4   0.2    1.3  1  Abhydrolase_1  alpha/beta hydrolase fold
    3.4e-08   34.4   2.4    4.4e-08   34.0   2.4    1.2  1  Abhydrolase_6  Alpha/beta hydrolase family
    4.9e-05   22.7   0.0    6.4e-05   22.3   0.0    1.1  1  Hydrolase_4    Serine aminopeptidase, S33


Domain annotation for each model (and alignments):
>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.4   0.2   4.5e-18   2.7e-14       2     142 ..      40     176 ..      39     205 .. 0.87

  Alignments for each domain:
  == domain 1  score: 53.4 bits;  conditional E-value: 4.5e-18
                    EEEEE-STTTCGGGGTTGHHHHHHHHTTSEEEEEEETTSTTSSSTTTGB.CHHSHHHHHHHHHHHHHHCTTSSEEEEEETHHHHHHHHHHHHHGGG CS
  Abhydrolase_1   2 vlvilhGlpgssdvwaerglapaLakdgfdvillDlrGvgySspapacinddygtasvaddldrildalgddkltlvGhSmGGmialayaaeyper 97 
                    +++++hG+p s d +a   ++p L k+g++vi++ lrG+g++++     +   + a++  d+ +++da  +dk +  G+++G+ ++  +aa+ per
     EEA20621.1  40 AVILVHGFPYSIDAFAS--VVPLLTKQGYRVIVPYLRGYGETTFIYPDTPRSAEQAALGSDIIALMDAIHIDKAIFAGYDWGTVVVNVAAALWPER 133
                    79***************..*************************9987776667788999************************************ PP

                    EEEEEEESECSSCCHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHH CS
  Abhydrolase_1  98 Vkalvllgaidpaaslieaqrqqaksfpdffdgyaadcarnpagp 142
                    +++ v+ ++  + +  ++++   +  + ++++ y++++   +++ 
     EEA20621.1 134 CNGHVAANS--YLIQNRSTAWVPLDPDSEALRWYYYVFLTARGAA 176
                    ********9..7777777776666666666666666666666555 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.0   2.4   7.3e-12   4.4e-08       1     172 [.      41     249 ..      41     304 .. 0.46

  Alignments for each domain:
  == domain 1  score: 34.0 bits;  conditional E-value: 7.3e-12
                    EEEE--GC.....GCHHHHHHHHCCT.CEEEEE--TTSTS-....GGCS--HHHC...HHHHHHHCCTT..TTSEEEEEETCHHH...HHHHHHHC CS
  Abhydrolase_6   1 vlllHGagssassWlvapLaallaag.vhvlapDlpGhGrs....dpppldledl...adlaalldelaagggpvvlvGHSlGGa...lalaaapl 85 
                    v+l+HG+++s ++++  ++++ll+++ ++v++p l+G+G++    ++ p + e +    d+ al d++    ++++  G+++G++   +a+a   l
     EEA20621.1  41 VILVHGFPYSIDAFA--SVVPLLTKQgYRVIVPYLRGYGETtfiyPDTPRSAEQAalgSDIIALMDAI--HIDKAIFAGYDWGTVvvnVAAA---L 129
                    79******9999997..6666666666888*********44333322222222212336667777777..59999********995443333...3 PP

                    C.................EEEEES-..----TTT...........S----TTHHHHHHTT-C......CCCH.CCH...S-HSCCCCHHHCCCCHC CS
  Abhydrolase_6  86 a...............lvvgvlldppptalpagl...........laaalelllallallrl......lawl.sre...plprlfladedadaawr 145
                                    ++++ +  p    +p+++           ++ a+ l+  + a++r+       +w  + e   +l+ + ++++d+  ++ 
     EEA20621.1 130 WpercnghvaansyliQNRSTAWVP---LDPDSEalrwyyyvfltARGAAGLASSPKAWARSlwqknsIGWNfT-EeylDLTATAFENPDYVDIVL 221
                    3554444444444454444444444...4444444333333333211111111111111111222222333321.134434445555555444444 PP

                    HCCCGHHHHCCHHC.HTTCCHHTT-TTG CS
  Abhydrolase_6 146 arlarlaallaglg.llpaaawadlpvp 172
                      ++  + +++g+  +  +aa  d+ +p
     EEA20621.1 222 NFYRNRLLYAPGDPkYVDLAARLDAQPP 249
                    4444444444433322222222222222 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.3   0.0   1.1e-08   6.4e-05       5     115 ..      39     148 ..      35     181 .. 0.87

  Alignments for each domain:
  == domain 1  score: 22.3 bits;  conditional E-value: 1.1e-08
  Hydrolase_4   5 avvvlvHGlaehsgryaelaeaLaaqGfavyalDhrGhGrse...gkrghvpsfddyvdDlaafvekvkeehpelplfllGhSmGGliallyllrypd 99 
                   +v+lvHG+  +++++a ++  L++qG+ v+    rG+G++    + + + ++   +  D+ a+++++       + +  G  +G +++  +++  p+
   EEA20621.1  39 SAVILVHGFPYSIDAFASVVPLLTKQGYRVIVPYLRGYGETTfiyPDTPRSAEQAALGSDIIALMDAIH----IDKAIFAGYDWGTVVVNVAAALWPE 132
                  589***************************************999888888999999999999999888....6678999******999999999999 PP

  Hydrolase_4 100 kvaglilsaPalkika 115
                  +++g + +++ l  + 
   EEA20621.1 133 RCNGHVAANSYLIQNR 148
                  9999999988876554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (325 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       342  (0.0190752); expected 358.6 (0.02)
Passed bias filter:                      316  (0.0176251); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 2171.78
//
Query:       EEA20622.1  [L=521]
Description: feruloyl esterase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   3.9e-101  339.3   1.7   4.5e-101  339.1   1.7    1.0  1  Tannase        Tannase and feruloyl esterase
    8.8e-08   31.9   0.0    0.00034   20.2   0.0    2.2  2  Peptidase_S9   Prolyl oligopeptidase family
     0.0024   17.2   0.0      0.008   15.5   0.0    1.7  2  Hydrolase_4    Serine aminopeptidase, S33
  ------ inclusion threshold ------
      0.015   14.9   0.2       0.14   11.8   0.1    2.4  2  Abhydrolase_1  alpha/beta hydrolase fold


Domain annotation for each model (and alignments):
>> Tannase  Tannase and feruloyl esterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  339.1   1.7    1e-104  4.5e-101       1     469 []      68     521 .]      68     521 .] 0.89

  Alignments for each domain:
  == domain 1  score: 339.1 bits;  conditional E-value: 1e-104
     Tannase   1 ckvtgeispvdrkapqikfevelPs.ewngrflqvGgggf.agniqtttskaevlskalarGfatagtdaGhdasda.......dasfa.knpealldf 89 
                 c vt +  + ++ + q   +v+lP  +wngrf   Gg  +  g  + t       +  +++G+  a+tdaG   +         +a  +  n +al+df
  EEA20622.1  68 CDVT-VFLTHSGAQNQATVKVWLPLqDWNGRFQANGGSAYvTGEFDLTL------GPTVKDGYSAASTDAGLGFNFTspgswalNAD-GsVNFDALADF 158
                 7777.6666777778999******99*******9999887256666666......7899***********96533333456664444.34899****** PP

     Tannase  90 ayralkkvtdvakaLvkafygkspersYfeGcSdGGRegltaaqRypddydGiiagapalnfvqlalygafsaraeatddldaiisaaelkviakavla 188
                 +yr+++ ++ v+k+L+++fyg  pe+sY++GcS+GGR+g+ aaqRyp+ +dGi+agapa+n+++  ++  + + +  +  +++++s +el+  ++a+++
  EEA20622.1 159 SYRSVHDMAIVGKELTRQFYGTRPEYSYWNGCSTGGRQGMAAAQRYPELFDGILAGAPAINWAKYVVAEQWPQVVMHQ--DQTFPSTCELNFFSDAAIK 255
                 ****************************************************************99999988776666..68***************** PP

     Tannase 189 aCDalDgvaDglvqdpelCklafe...vesllCeagtgsngdscltaaqvavvaaiyeglknvlssGerlylglevaseetdaagelasstakwelgst 284
                 +CD +Dgv Dg++ dp +C  ++    +++++C+++        +t+  + vv+++++g+ +  ++G+ l +gl+v +++     +l+++t+      t
  EEA20622.1 256 ECDEMDGVKDGIITDPGKCSYDPLksvGQVVQCNGQN-----IIITNSTATVVKKALQGPLD--HTGQPLWYGLNVGASLD----SLVNTTTDANGTRT 343
                 **********************9889999****4444.....789***************66..***********877554....22333333222236 PP

     Tannase 285 vkaesaaeealrnvvakfardlnldlsslklealkerkttslvelsslidatepdlskfrsrgGklilyhgtaDpvvspadsikyyesveaklgadlee 383
                 +++     +++++++a   rd ++++++++ ++  +   +s  e+  +i  +++dls f+ +gGkl+++hg +D  + p ++i y e+ve ++g++ ++
  EEA20622.1 344 GYPFFVNDQWIKYFLA---RDPDYNTEQIDYGTFFDLFWQSYTEYDGIIGIDDADLSSFHHQGGKLLMWHGLSDQLIFPGGTIDYRERVEHRMGGA-KK 438
                 7899999*****9999...*****************999********************************************************9.** PP

     Tannase 384 leeFarlylvpGvaHcgggsgtsai..dlLealvdWVEngkaPerlvatkakkekksagrtrplcryPkiakykgkgsvekassftcv 469
                 +++F+rl+l+pGv+Hcg+g++  a   d ++alv+WVE+g+aP+ + at + ++k      r +c yP+ia y+g g+ ++a sf cv
  EEA20622.1 439 TNDFFRLFLAPGVDHCGAGTTIGATpdDPFKALVNWVEHGEAPDLISATVNDATK----AERIVCAYPQIATYQG-GDPKCAASFRCV 521
                 *******************96555588***********************99999....7799************.***********7 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.0   7.5e-08   0.00034      43     108 ..     161     227 ..     154     250 .. 0.88
   2 !    9.4   0.0   0.00015      0.66     101     189 ..     353     456 ..     348     476 .. 0.82

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 7.5e-08
                   HHHHHHHHHHHHHHHTT.S--GGGEEEEEETHHHHHHHHHHHH-GGG-SEEEEESE---CCCHHCST CS
  Peptidase_S9  43 nefdDfiaaaealakeg.yvdserlaitGgSyGGyltgaalnqrpdlFkaavaevpvvdvlrydsdt 108
                   ++++D+  + ++l+ ++  + +e  +  G S GG   +aa+ + p+lF++++a++p +++ +y   +
    EEA20622.1 161 RSVHDMAIVGKELTRQFyGTRPEYSYWNGCSTGGRQGMAAAQRYPELFDGILAGAPAINWAKYVVAE 227
                   5788999999*******77999999************************************998774 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.00015
                   CCCHHCSTTS.THHHCCCC--TTT....CHHHHHHHHHH-CGGG--...---EEEEEEETT-SSS-THHHHHHHHHHH......--S-S.EEEEEET CS
  Peptidase_S9 101 vlrydsdtdl.lteeymewgnpee....neegykelspyspldnvk...aypplLlihGlaDdrvppaealklvaaLq......kkgkn.vlllifp 182
                   +++y +  d  +++e  ++g+  +    + ++y+ +  ++++d      +  +lL+ hGl D+ + p  ++ + ++++      kk ++ ++l   p
    EEA20622.1 353 WIKYFLARDPdYNTEQIDYGTFFDlfwqSYTEYDGIIGIDDADLSSfhhQGGKLLMWHGLSDQLIFPGGTIDYRERVEhrmggaKKTNDfFRLFLAP 449
                   6677777666777777777776444444888999999999988876889**********************************9888888******* PP

                   TS-SSTT CS
  Peptidase_S9 183 degHgvg 189
                   + +H ++
    EEA20622.1 450 GVDHCGA 456
                   ****443 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   1.8e-06     0.008      77     127 ..     184     234 ..     157     251 .. 0.77
   2 ?   -2.0   0.0      0.39   1.8e+03     194     219 ..     406     431 ..     400     441 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1.8e-06
  Hydrolase_4  77 plfllGhSmGGliallyllrypdkvaglilsaPalkikaklkappllklll 127
                    ++ G S+GG   +++++ryp+ ++g+   aPa+++++++ a ++ ++++
   EEA20622.1 184 YSYWNGCSTGGRQGMAAAQRYPELFDGILAGAPAINWAKYVVAEQWPQVVM 234
                  457889*******************************99987877777654 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.39
  Hydrolase_4 194 llllhGeaDkvvdpeasrelyerlgs 219
                  ll+ hG +D+++ p+++ ++ er+ +
   EEA20622.1 406 LLMWHGLSDQLIFPGGTIDYRERVEH 431
                  7999********99999777766654 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.1   3.1e-05      0.14      78     129 ..     188     245 ..     100     261 .. 0.74
   2 ?    0.3   0.0     0.097   4.3e+02     209     239 ..     395     431 ..     302     442 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3.1e-05
                    EEETHHHHHHHHHHHHHGGGEEEEEEESE......CSSCCHHHHHHHHHHHHHHCHHC CS
  Abhydrolase_1  78 vGhSmGGmialayaaeyperVkalvllga......idpaaslieaqrqqaksfpdffd 129
                     G+S GG++++a+a++ype  +++ + ++         a  + +   +q+++fp + +
     EEA20622.1 188 NGCSTGGRQGMAAAQRYPELFDGILAGAPainwakYVVAEQWPQVVMHQDQTFPSTCE 245
                    49*********************99998885544444455666666666666665555 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.097
                    HHHS......EEEEEEETTCSSSCHHHHHHHHHCHTS CS
  Abhydrolase_1 209 nvla......ptlvisgtsDplvppkaledlaqllpk 239
                    + ++      + l+++g sD+l+ p+   d+++   +
     EEA20622.1 395 DLSSfhhqggKLLMWHGLSDQLIFPGGTIDYRERVEH 431
                    22223334449999*******9999999998887666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (521 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       402  (0.0224218); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.30s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 3530.29
//
Query:       EEA20623.1  [L=243]
Description: hypothetical protein PMAA_044530 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.3e-07   29.0  14.5    1.2e-06   28.5  14.5    1.2  1  Zn_clus        Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.017   14.9   0.8      0.037   13.8   0.8    1.6  1  TRAF_BIRC3_bd  TNF receptor-associated factor BIRC3 binding d


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.5  14.5   1.3e-10   1.2e-06       1      37 [.       6      41 ..       6      44 .. 0.90

  Alignments for each domain:
  == domain 1  score: 28.5 bits;  conditional E-value: 1.3e-10
                SS-HHHHHCT---ST.SSSS-HHHHHCTHHHCCCCTCC CS
     Zn_clus  1 haCdnCrkkKvKCda.kkPaCsnCkklnleCtfysess 37
                +aC +Cr +K +Cd+  ++ Cs C++++++C+ ys++ 
  EEA20623.1  6 QACHSCRDRKKRCDRaLQG-CSDCQRRQVQCQ-YSQKV 41
                69*************7777.************.99985 PP

>> TRAF_BIRC3_bd  TNF receptor-associated factor BIRC3 binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.8   4.1e-06     0.037      38      62 ..      37      61 ..      27      62 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 4.1e-06
  TRAF_BIRC3_bd 38 erqrrldqekieaLekKvrqLerti 62
                     q+ +++ ++e+Le+K+ +Ler+i
     EEA20623.1 37 YSQKVEERGMVESLEQKLMSLERSI 61
                   56999******************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (243 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1029  (0.0573931); expected 358.6 (0.02)
Passed bias filter:                      558  (0.0311228); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 1661.56
//
Query:       EEA20624.1  [L=268]
Description: hypothetical protein PMAA_044540 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      2e-24   86.4   2.8    2.6e-24   86.0   2.8    1.1  1  Mod_r            Modifier of rudimentary (Mod(r)) protein
  ------ inclusion threshold ------
       0.14   11.7   5.5       0.21   11.1   5.5    1.3  1  PspA_IM30        PspA/IM30 family
       0.24   11.0   1.2        6.3    6.5   0.1    2.4  2  Nbl1_Borealin_N  Nbl1 / Borealin N terminal
       0.29   11.7   4.5       0.72   10.4   4.5    1.7  1  Caskin-Pro-rich  Proline rich region of Caskin proteins


Domain annotation for each model (and alignments):
>> Mod_r  Modifier of rudimentary (Mod(r)) protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.0   2.8   5.8e-28   2.6e-24       2     133 ..     104     243 ..     103     254 .. 0.94

  Alignments for each domain:
  == domain 1  score: 86.0 bits;  conditional E-value: 5.8e-28
       Mod_r   2 klSkeeLqelledeeklealvktlpevkqlkeekeellaeneslaeknlslepeleelrselqekleelkelekefeekeqeldellqkfspdallarL 100
                 ++++ eLq +l+++ +l+al +  p+  + ++ +++ l++n++la++ l+le ++ +lr+ +++ l + ++le ++++k++e+d++l+++sp+al++rL
  EEA20624.1 104 NKTTPELQSILSNPTLLSALSTLHPSYPASQQVLQSHLDSNKALAQHVLELESRVANLRATTESLLLNHQSLEVSWRKKQAEMDAALEPWSPKALYQRL 202
                 7899****************9777*************************************************************************** PP

       Mod_r 101 qtavaeaeeeSealaeefle........geieldeFvkefk 133
                  +avae+e  + a++e+fle        +++e+ ++v++ +
  EEA20624.1 203 AAAVAEQEAICHAVEESFLEgdhhsgraTDKEVTDWVRRIR 243
                 *******************9999999999999999998765 PP

>> PspA_IM30  PspA/IM30 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   5.5   4.7e-05      0.21      16      93 ..     135     210 ..     132     257 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 4.7e-05
   PspA_IM30  16 elldkaeDPekileqairdmqselakarqalaqviarqkqlerkleeqkeqa.kklekkAkaALtkgeeeLArealaei 93 
                 ++l+++ D++k l q++ +++s +a++r + ++++ ++++le   +++++++ ++le    +AL   ++ LA++++++ 
  EEA20624.1 135 QVLQSHLDSNKALAQHVLELESRVANLRATTESLLLNHQSLEVSWRKKQAEMdAALEPWSPKAL---YQRLAAAVAEQE 210
                 799***************************************9998888777356777777777...456777776664 PP

>> Nbl1_Borealin_N  Nbl1 / Borealin N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.1    0.0014       6.3       6      28 ..     147     169 ..     143     175 .. 0.87
   2 ?    2.9   0.1     0.019        86      10      26 ..     232     248 ..     231     256 .. 0.90

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0014
  Nbl1_Borealin_N   6 LenfdlEveeRirrlraelelll 28 
                      L++  lE+e+R+  lra +e+ll
       EEA20624.1 147 LAQHVLELESRVANLRATTESLL 169
                      778889**************998 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.019
  Nbl1_Borealin_N  10 dlEveeRirrlraelel 26 
                      d+Ev++ +rr+r+e ++
       EEA20624.1 232 DKEVTDWVRRIRTEGAK 248
                      99**********99765 PP

>> Caskin-Pro-rich  Proline rich region of Caskin proteins
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   4.5   0.00016      0.72      53      85 ..       7      40 ..       1      44 [. 0.77

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00016
  Caskin-Pro-rich 53 aeknvnR.sqsfavRarkkGPPPPPPkRlssvss 85
                     +++ ++  s sf +  +   PPPPPPk  s  +s
       EEA20624.1  7 PQQSAGWsSSSFQLPVHSETPPPPPPKPDSHEAS 40
                     55555554889****************8886655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (268 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       980  (0.05466); expected 358.6 (0.02)
Passed bias filter:                      605  (0.0337442); expected 358.6 (0.02)
Passed Vit filter:                        67  (0.00373696); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.38
# Mc/sec: 2134.85
//
Query:       EEA20625.1  [L=311]
Description: aldehyde reductase (AKR1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.7e-47  161.4   0.0    9.8e-47  159.6   0.0    1.7  1  Aldo_ket_red  Aldo/keto reductase family


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  159.6   0.0   5.5e-51   9.8e-47       2     293 ..      17     285 ..      16     286 .. 0.94

  Alignments for each domain:
  == domain 1  score: 159.6 bits;  conditional E-value: 5.5e-51
                   EEEE-SSS-ST.TS-HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH-TTTGGG-EEEEEE--SSSTTSSSS-HHHHHHHHHHHHHHHT CS
  Aldo_ket_red   2 lglGtwqlgskeeiskeealellrraleaGinffDtAevYgkgqseellGealkksrkkreeviiatKvdlrdaeiksglskeniresleeslkrLg 98 
                   lg+Gtwq       + e ++++++ a++ G++++DtA+vY     ee +G+a+ +s+ +r e++++tK+      ++ ++ ++++ ++++eslk L+
    EEA20625.1  17 LGFGTWQ-------DAEAQVDAVKEAIKVGYRHIDTARVY---GTEEAVGKAIRESGIPRNELFVTTKL------WNHQHDPKDVPKAIDESLKDLQ 97 
                   7888883.......56788999******************...8899**********************......********************** PP

                   -S-EEEEEE-S--TTS-..................HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHHHHTTT--EEEEE-B-BTT-HHHHTTHHHH CS
  Aldo_ket_red  99 tdyvDllllHrpdpslp.................sieevldaleelvkeGkiraiGvSnfsveqlekakkkkkvkivavqveynllreleeegllel 178
                    dyvDl+l+H p  + +                 +  ++++a+e+l + Gk+ aiG+Snfs +q+e++ +   v +++ q+e++++  l++++ +  
    EEA20625.1  98 MDYVDLFLMHFPVAWKSgnglfpkengkpavvdiDFVDTYKAMEKLLDTGKVEAIGISNFSKAQMEHLFTNTSVVPAVHQIECHPW--LQQTEFVNW 192
                   ********************************************************************9*****************..********* PP

                   HHHTT-EEEEBSTTGGGTTGTTTSS---SSSCCC-------TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTSTT-SEEEE--SSHHHHHHHHG CS
  Aldo_ket_red 179 ckkkgvpliaysplggGlltgkyqseedkedkeprkdlkrdertsknldaaeelselakehgvslaqlalryalsqpavgivipgasnieqlednld 275
                    + kg+ +  ysp+g+        ++e ++ k+            ++l  ++ l e++k++g+s aq+al++ +    + +v+p++++++++++nl+
    EEA20625.1 193 HRGKGIHITQYSPFGN--------QNEIYGAKHL-----------GKLIETPMLVEIGKKYGKSGAQVALAWGI--TLGHSVLPKSKTPKRIQENLQ 268
                   ***************4........3344443323...........4457899**********************..********************9 PP

                   GGG----HHHHHHHHHHH CS
  Aldo_ket_red 276 alelklseeevaeldell 293
                      +kls+e++++++ ++
    EEA20625.1 269 GD-FKLSDEDMKKIQTIN 285
                   87.***********9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (311 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       636  (0.0354733); expected 358.6 (0.02)
Passed bias filter:                      563  (0.0314016); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2186.53
//
Query:       EEA20626.1  [L=163]
Description: DUF636 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      9e-07   29.2   1.3    1.8e-06   28.2   1.1    1.7  1  GFA         Glutathione-dependent formaldehyde-activating enz
  ------ inclusion threshold ------
       0.26   11.2   4.9       0.99    9.3   0.3    2.2  2  PHD_Oberon  PHD - plant homeodomain finger protein


Domain annotation for each model (and alignments):
>> GFA  Glutathione-dependent formaldehyde-activating enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.2   1.1     2e-10   1.8e-06       2      69 ..      28     103 ..      27     126 .. 0.78

  Alignments for each domain:
  == domain 1  score: 28.2 bits;  conditional E-value: 2e-10
         GFA   2 lChCsdCrkasgsaftanavvkaealelleg..elkeykkt......adsgnkvtrsfCpeCgsplyseesaapev 69 
                 lC Cs Crk +g   ++n+   a+ l++ +g   +k+y+        ++++   +rsfC++C + l+   +  pe+
  EEA20626.1  28 LCACSICRKVAGYNGSVNLGGIADTLKIKKGeeLIKKYNAIknrgkrNEETCSSERSFCSNCSTMLWLWDHHWPEL 103
                 7*****************************99977888765222211233334578**********9877666655 PP

>> PHD_Oberon  PHD - plant homeodomain finger protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.6    0.0054        48      28      39 ..      27      38 ..       8      48 .. 0.74
   2 ?    9.3   0.3   0.00011      0.99      16      33 ..      75      92 ..      64      95 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.0054
  PHD_Oberon 28 keCsCviCskfd 39
                + C+C iC+k+ 
  EEA20626.1 27 QLCACSICRKVA 38
                568888887764 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.00011
  PHD_Oberon 16 ecdicskekgFCkeCsCv 33
                + + cs+e++FC++Cs +
  EEA20626.1 75 NEETCSSERSFCSNCSTM 92
                5579***********976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (163 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       856  (0.0477439); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.23s 00:00:00.69 Elapsed: 00:00:00.42
# Mc/sec: 1176.35
//
Query:       EEA20627.1  [L=96]
Description: cytochrome c oxidase assembly protein Cox19, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-05   25.4   0.6    1.8e-05   24.7   0.6    1.3  1  CHCH      CHCH domain
     0.0015   18.8   2.1     0.0066   16.8   0.3    2.1  2  COX17     Cytochrome C oxidase copper chaperone (COX17)
  ------ inclusion threshold ------
      0.013   15.8   2.2        0.3   11.4   0.8    2.0  2  Pet191_N  Cytochrome c oxidase assembly protein PET191
      0.047   13.4   0.1      0.056   13.2   0.1    1.2  1  NDUF_B7   NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)


Domain annotation for each model (and alignments):
>> CHCH  CHCH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.6     4e-09   1.8e-05       1      34 [.      31      65 ..      31      66 .. 0.94

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 4e-09
                THHHHHHHHHHHHHCTS.STTTTHHHHHHHHHHHC CS
        CHCH  1 CgeefkeylkClkdnsd.efskCrkefeafkeCvk 34
                C+   ++ylkClk+++  ++++Crk+ + +  C++
  EEA20627.1 31 CKHLIQNYLKCLKSQGGvNNEDCRKLAKGYLGCRM 65
                99999************66**************99 PP

>> COX17  Cytochrome C oxidase copper chaperone (COX17)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.3   1.5e-06    0.0066      27      45 ..      28      46 ..      22      48 .. 0.86
   2 ?    1.7   0.1     0.073   3.3e+02      26      40 ..      49      63 ..      47      68 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 1.5e-06
       COX17 27 eekCkelieahkaCmrslG 45
                + +Ck+li+++ +C++s G
  EEA20627.1 28 DGECKHLIQNYLKCLKSQG 46
                349*************998 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.073
       COX17 26 eeekCkelieahkaC 40
                ++e+C++l + +  C
  EEA20627.1 49 NNEDCRKLAKGYLGC 63
                4559********999 PP

>> Pet191_N  Cytochrome c oxidase assembly protein PET191
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   0.2   0.00068         3      40      57 ..      28      45 ..      24      50 .. 0.84
   2 ?   11.4   0.8   6.6e-05       0.3      30      56 ..      40      66 ..      40      72 .. 0.90

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.00068
    Pet191_N 40 peeCkqlrkayfeCkrgl 57
                + eCk+l ++y +C +++
  EEA20627.1 28 DGECKHLIQNYLKCLKSQ 45
                569***********8775 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 6.6e-05
    Pet191_N 30 eClkekaeelpeeCkqlrkayfeCkrg 56
                +Clk++    +e+C++l k y  C+++
  EEA20627.1 40 KCLKSQGGVNNEDCRKLAKGYLGCRMD 66
                69**998888999************87 PP

>> NDUF_B7  NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.1   1.2e-05     0.056      13      56 ..      24      68 ..      19      75 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.2e-05
     NDUF_B7 13 plkeRDyCAhlLiplnkCrrenfp.lpwkCehekhayekCqyedy 56
                pl++   C hl  ++ kC + +   +  +C++    y  C+++  
  EEA20627.1 24 PLDHDGECKHLIQNYLKCLKSQGGvNNEDCRKLAKGYLGCRMDKN 68
                5666668***********9999887999************98865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (96 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       343  (0.019131); expected 358.6 (0.02)
Passed bias filter:                      295  (0.0164538); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.47
# Mc/sec: 610.48
//
Query:       EEA20628.1  [L=794]
Description: UPF0171 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   3.9e-156  520.5   0.0   6.1e-156  519.9   0.0    1.3  1  NPR3             Nitrogen Permease regulator of amino acid tr
  ------ inclusion threshold ------
      0.069   13.9   2.1        7.1    7.5   0.9    2.5  2  Ribosomal_S30AE  Sigma 54 modulation protein / S30EA ribosoma
       0.25   11.1   4.4      0.061   13.1   0.6    1.9  2  Pox_Ag35         Pox virus Ag35 surface protein


Domain annotation for each model (and alignments):
>> NPR3  Nitrogen Permease regulator of amino acid transport activity 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  519.9   0.0    1e-159  6.1e-156       1     466 [.     155     593 ..     155     594 .. 0.93

  Alignments for each domain:
  == domain 1  score: 519.9 bits;  conditional E-value: 1e-159
        NPR3   1 gfdseflaellsPerelcntrFeltvDdlaFlGlPvhvdedgkwrkskkkkkkskrkrssrskekkskesskksesssksesseekksskeseeseeke 99 
                 g++se++++llsP+r+++++rFe+ ++dlaF+G+Pv+v++dg+wrk+++     +rkr++++++ + k++ + + +  +++ +++ +s+++  +s++++
  EEA20628.1 155 GLPSEVWEKLLSPSRAWHKRRFEIGINDLAFVGWPVFVRDDGHWRKKSR-----RRKRKKTKSGGEGKQHGSGEAKIGQDDDDANLNSDNDVPDSTQSS 248
                 789********************************************54.....666666667777777777888888888888888888888888888 PP

        NPR3 100 sneeeeeeededdeesekeeeekedkkknltmFhlvfvlnPplseynsrvdemYenvvkklsaalkyeQaksdYVskEcekilklkekalkeskklkel 198
                 ++e++ +++d +d++ ++++ + e++k+ ++mF++vfv+ Pp +ey+ +++emYe+v+kk+s+alkyeQ++sdYV+kE+++il++ke+a++++ + ++l
  EEA20628.1 249 RDEDNADKTDIEDNA-DSQTGSPESDKDTMSMFNVVFVMAPPVLEYSIHLKEMYEHVIKKFSKALKYEQDHSDYVWKEAQRILQIKERARERDVSGENL 346
                 888888888888876.44888899*************************************************************************** PP

        NPR3 199 yreilekSsLAraltelyesisknkiAslelnddvtislqiPiktefsklpnekeeavlpgsyltsilneseseedee..eeeekfLeknyaLLlLdde 295
                   e+++kSsLA+a++ ++++isk++iA+++l ++ + ++qiP++t++++lp+ ++++ l g++lt++ +   ++++    e ++++L+k++aLLlL+ e
  EEA20628.1 347 HDELVSKSSLAAAIHSVFDKISKSDIAFVSL-KSRSADFQIPPTTSIAELPSSNDTS-LAGMWLTTANS--VTADQGAeiEVPNQVLAKHFALLLLESE 441
                 *******************************.999********************98.*********44..444433346899**************** PP

        NPR3 296 kkiikelekssaeddeltvllaelvralkptlslaeyaslldedleeeqvsesnslelsqirslarhLiywRrArvIdplssrdvYivsPladlskleq 394
                 ++i++ l     + +el+++l +++r+++p++s+a             q+s+ + ++l++i++la+hLiywRrAr+I+pl++rd+YivsP++dls+l++
  EEA20628.1 442 ASIMEAL-----KGSELAPALSHYIRSSRPNKSFA-------------QISALSGIPLDTIHDLAQHLIYWRRARAIPPLHQRDTYIVSPNCDLSQLKK 522
                 ******9.....5679*******************.............6677799******************************************** PP

        NPR3 395 asaeFkekFpslPsLpkfLsaLSsskprpfssiipskehrelYleaLaWLlrkglvtqlltfarirvdkeik 466
                 a+++++++Fp+lPsLpk+LsaLS ++prp++++ipsk+h+e+Y+++LaWLlr+g+vtql+tf r++v++eik
  EEA20628.1 523 ATQSYATTFPTLPSLPKMLSALS-GTPRPYATFIPSKDHKETYFAILAWLLRGGWVTQLRTFSRVKVTPEIK 593
                 ***********************.89*********************************************9 PP

>> Ribosomal_S30AE  Sigma 54 modulation protein / S30EA ribosomal protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   0.9    0.0012       7.1      14      76 ..     300     369 ..     296     370 .. 0.69
   2 ?    5.1   0.0    0.0066        40       5      30 ..     583     610 ..     581     620 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0012
                      HHHHHHHHHCCGGGG.........-EEEEEEE.EEEEEEEEEEECTTEEEEEEE.EESSHHHHHHHHHHHHHH CS
  Ribosomal_S30AE  14 lkeyvekklekleky......f..ieadVtls.kkkkvevtirlakgkviraee.esedlyaaidlavdkler 76 
                      + e+v kk++k  ky      +   ea+ +l+ k     ++ r ++g+ ++ e  + ++l aai++++dk+ +
       EEA20628.1 300 MYEHVIKKFSKALKYeqdhsdYvwKEAQRILQiK---ERARERDVSGENLHDELvSKSSLAAAIHSVFDKISK 369
                      7799***********6554431567777777742...334443346777775542459************976 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0066
                      ECTS---HHHHHHHHHHH..CCGGGG.- CS
  Ribosomal_S30AE   5 grnievtdalkeyvekkl..eklekyfi 30 
                      +  ++vt+++k +ve+k+  e leky++
       EEA20628.1 583 FSRVKVTPEIKFVVEQKMrkEQLEKYIA 610
                      66799*************7777889964 PP

>> Pox_Ag35  Pox virus Ag35 surface protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.2      0.85   5.1e+03     108     108 ..      83      83 ..      49     135 .. 0.46
   2 ?   13.1   0.6     1e-05     0.061      56     123 ..     199     266 ..     150     273 .. 0.66

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 0.85
    Pox_Ag35 108 e 108
                 +
  EEA20628.1  83 S 83 
                 0 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 1e-05
    Pox_Ag35  56 rattprkkpakkekkkkeeekeeaaeeeeledseede.enendedeseesvqaeeeksnesteddadel 123
                 r +++r+k  kk+k   e +++   e++  +d+++ + +++nd+++s +s + e+++ +++ ed+ad+ 
  EEA20628.1 199 RKKSRRRK-RKKTKSGGEGKQHGSGEAKIGQDDDDANlNSDNDVPDSTQSSRDEDNADKTDIEDNADSQ 266
                 45555555.444444444455544555555555555505577888888777766665555566777654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (794 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       948  (0.0528752); expected 358.6 (0.02)
Passed bias filter:                      553  (0.0308439); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.73u 0.28s 00:00:01.01 Elapsed: 00:00:00.44
# Mc/sec: 5390.79
//
Query:       EEA20629.1  [L=821]
Description: La domain family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-18   66.6   0.1    2.6e-18   65.8   0.1    1.4  1  La        La domain


Domain annotation for each model (and alignments):
>> La  La domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.8   0.1   1.5e-22   2.6e-18       1      55 [.     655     707 ..     655     711 .. 0.93

  Alignments for each domain:
  == domain 1  score: 65.8 bits;  conditional E-value: 1.5e-22
                 HHHHHHHHHHTT-TTT-HHHHHHHTTSTTS---HHHHHTSSHHHHHHSSHHHHHH CS
          La   1 ilkQvEfYFSdeNLpkDkFLrkkmdkdpegwVplsliasfkrmkkltkdveliae 55 
                 i  Q+E+YFS +NL+kD +Lrk+md+  +g+V ls+ia fkr+++lt+d+e++ +
  EEA20629.1 655 IQMQLEYYFSVDNLCKDLYLRKHMDS--QGFVRLSFIAGFKRIRHLTEDYEMLRH 707
                 678**********************9..9********************998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (821 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1563  (0.0871772); expected 358.6 (0.02)
Passed bias filter:                      399  (0.0222544); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                        23  (0.00128284); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 1.15u 0.37s 00:00:01.52 Elapsed: 00:00:00.54
# Mc/sec: 4602.95
//
Query:       EEA20630.1  [L=820]
Description: La domain family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-18   66.6   0.1    2.6e-18   65.8   0.1    1.4  1  La        La domain


Domain annotation for each model (and alignments):
>> La  La domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.8   0.1   1.5e-22   2.6e-18       1      55 [.     655     707 ..     655     711 .. 0.93

  Alignments for each domain:
  == domain 1  score: 65.8 bits;  conditional E-value: 1.5e-22
                 HHHHHHHHHHTT-TTT-HHHHHHHTTSTTS---HHHHHTSSHHHHHHSSHHHHHH CS
          La   1 ilkQvEfYFSdeNLpkDkFLrkkmdkdpegwVplsliasfkrmkkltkdveliae 55 
                 i  Q+E+YFS +NL+kD +Lrk+md+  +g+V ls+ia fkr+++lt+d+e++ +
  EEA20630.1 655 IQMQLEYYFSVDNLCKDLYLRKHMDS--QGFVRLSFIAGFKRIRHLTEDYEMLRH 707
                 678**********************9..9********************998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (820 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1561  (0.0870656); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                        23  (0.00128284); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 1.13u 0.38s 00:00:01.50 Elapsed: 00:00:00.53
# Mc/sec: 4679.10
//
Query:       EEA20631.1  [L=436]
Description: stomatin family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-30  105.9   0.7    5.4e-30  104.7   0.7    1.6  1  Band_7    SPFH domain / Band 7 family
    4.4e-25   87.5   1.2    1.1e-24   86.2   1.2    1.8  1  Band_7_C  C-terminal region of band_7
  ------ inclusion threshold ------
       0.04   13.7   0.6       0.67    9.8   0.0    2.4  2  DRTGG     DRTGG domain
      0.073   12.3   0.3       0.11   11.7   0.3    1.3  1  Pox_A11   Poxvirus A11 Protein


Domain annotation for each model (and alignments):
>> Band_7  SPFH domain / Band 7 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.7   0.7   1.2e-33   5.4e-30       3     177 ..      91     260 ..      89     261 .. 0.97

  Alignments for each domain:
  == domain 1  score: 104.7 bits;  conditional E-value: 1.2e-33
      Band_7   3 ieegevgvvvrfGklsrvlepGlhfilPfgrsvt.vvsvrvqtldvsvsltvptkDglpvtidvtviyrvpddapklvaaveresanldnlirrvlesa 100
                 ++++ + +v+r Gk +r+lepGl + +Pf+++++ v s++   ++++  ++++t+D++ + +d++++ rv  da k+++ v    ++ +  i+++++ +
  EEA20631.1  91 VPQQTAWIVERMGKFHRILEPGLAILIPFIDRIAyVKSLKESAIEIPS-QNAITADNVTLELDGVLYTRV-VDAYKASYGV----EDAEYAISQLAQTT 183
                 8999******************************777888********.*********************.**********....************** PP

      Band_7 101 lrevisemtleellsnreelaeelknelneqlrkyGvevldvritdidpppevaqalaakqaaeaeaqaeiaraeae 177
                  r+ i+++tl+ +l++r+ l+ ++++++ne+++ +Gv +l+  i+di+ p+ v +a+++  +ae+ ++aei  +e++
  EEA20631.1 184 MRSEIGQLTLDHVLKERATLNTNITQAINEAAQDWGVVCLRYEIRDIHAPEGVVAAMHRQVTAERSKRAEILDSEGQ 260
                 **********************************************************************9988876 PP

>> Band_7_C  C-terminal region of band_7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.2   1.2   2.5e-28   1.1e-24       2      62 ..     310     372 ..     309     373 .. 0.95

  Alignments for each domain:
  == domain 1  score: 86.2 bits;  conditional E-value: 2.5e-28
    Band_7_C   2 kvaeaikkp..ggqeAvsLrvAeqYveaFgkLAkesntvilPanvgdvssmvaqalsiykkvs 62 
                 +va+ai++   ++q+AvsL+vAe+YveaFg+LAke++ v++P+nvgd+++m+a+als+y+kv+
  EEA20631.1 310 AVAKAIRDGqeNAQSAVSLSVAEKYVEAFGNLAKEGTAVVVPGNVGDIGGMIASALSVYGKVT 372
                 79****98888**************************************************96 PP

>> DRTGG  DRTGG domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.1     0.048   2.1e+02      25      90 ..     236     300 ..     219     311 .. 0.84
   2 ?    9.8   0.0   0.00015      0.67       8      53 ..     312     357 ..     308     368 .. 0.88

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.048
                 EE-SS-HHHHHHHHHTSEEEEEETT-HHHHHHHTT-TEEEEEEETT----HHHHHHHHHHT--EEE CS
       DRTGG  25 vvgamsvenmlerlkegdlvivpGDRediqlaaleagiaalilTgglepseevlklaeeaglpvls 90 
                 vv+am+ + + er k+ +++   G R+ ++  a   + + +il++++  +e++ +   ea+  +l+
  EEA20631.1 236 VVAAMHRQVTAERSKRAEILDSEGQRQSAINIAEGRK-QSVILASEALRAEKINRASGEAEAILLR 300
                 899************************9999988888.9999999998888888887777765555 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00015
                 -EEEE--..SS--E-EEEE-SS-HHHHHHHHHTSEEEEEETT-HHH CS
       DRTGG   8 aevlnggeeelrrvekvvvgamsvenmlerlkegdlvivpGDRedi 53 
                 a+ + +g+e+ +++ +++v+   ve++ +  keg++v+vpG+  di
  EEA20631.1 312 AKAIRDGQENAQSAVSLSVAEKYVEAFGNLAKEGTAVVVPGNVGDI 357
                 677788888998999**************************98887 PP

>> Pox_A11  Poxvirus A11 Protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.3   2.5e-05      0.11      69     130 ..     226     287 ..     157     323 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 2.5e-05
     Pox_A11  69 liPgedsPvtiiervsPqtklvddaaeseiilaeqqrqqrvnikvsekeavi.ekepiettki 130
                  i + + P  +++ ++ q++  ++++++ei+ +e qrq  +ni    k++vi  +e++++ ki
  EEA20631.1 226 EIRDIHAPEGVVAAMHRQVT-AERSKRAEILDSEGQRQSAINIAEGRKQSVIlASEALRAEKI 287
                 355668999******99999.888889*****************9987776526677766665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (436 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       616  (0.0343577); expected 358.6 (0.02)
Passed bias filter:                      344  (0.0191868); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2872.61
//
Query:       EEA20632.1  [L=1068]
Description: histone transcription regulator Hir1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.4e-84  283.2   0.1    2.7e-84  282.3   0.1    1.5  1  Hira         TUP1-like enhancer of split
    3.1e-26   91.1  30.6    2.6e-05   24.9   0.0    8.9  7  WD40         WD domain, G-beta repeat
      1e-13   51.3   0.0       0.36   11.1   0.0    6.0  7  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
    9.7e-11   41.3   0.1    3.3e-10   39.6   0.1    2.0  1  HIRA_B       HIRA B motif
    8.5e-06   25.6   2.2       0.44   10.6   0.0    5.4  5  PD40         WD40-like Beta Propeller Repeat
    3.3e-05   23.0   0.3        3.5    6.5   0.0    4.8  5  Ge1_WD40     WD40 region of Ge1, enhancer of mRNA-decapping p
  ------ inclusion threshold ------
       0.16   10.0   0.0       0.32    8.9   0.0    1.5  1  IKI3         IKI3 family


Domain annotation for each model (and alignments):
>> Hira  TUP1-like enhancer of split
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  282.3   0.1   1.1e-87   2.7e-84       1     222 []     743     977 ..     743     977 .. 0.99

  Alignments for each domain:
  == domain 1  score: 282.3 bits;  conditional E-value: 1.1e-87
        Hira   1 GrrllPplvlespasfLessgsyLlavtsvgllyvWnvkkkkvllppvslapllssssrssekeltrapavtsasltsnGvpivtlsngdgylydkslk 99 
                 Grrl+++lvle++a++Les+g +Ll++t+vg++yvWnvk+ ++++ppvsl+p+l+++++ +++++  apa+t a+++s+G+++v l+ng+gy+y+++++
  EEA20632.1 743 GRRLISALVLEAQAVILESKGPWLLCITAVGMCYVWNVKTVSSPHPPVSLQPVLDAATHVQTGQAILAPAITGARINSEGRIVVGLTNGEGYIYSSAMY 841
                 9************************************************************************************************** PP

        Hira 100 tWlrvsdswwalgsqywdsrdsstsssassas.............gilsalerktneevlrkgrakllqrlaktllekegfenleesvtlahlEnrlaa 185
                 tW+rvs++wwa+gsqyw+++d+s s+ +++ s             gi+++ler+t++e+l +gra++lqrl k ll++eg+e++e+sv++ahlEnr+aa
  EEA20632.1 842 TWQRVSEPWWAVGSQYWNTTDASVSNLQAMGSqngeeskkkkisaGIIPFLERNTTTETLLRGRAYFLQRLIKVLLSREGYESFESSVSIAHLENRMAA 940
                 ***************************998889****************************************************************** PP

        Hira 186 allLgsadEfkkwllaYakrLaeeglesrlrelckeL 222
                 al Lg+++Ef+ +l +Yakr+++egl+++++el+k L
  EEA20632.1 941 ALSLGAKEEFRLYLSMYAKRIGAEGLRGKVEELLKAL 977
                 **********************************976 PP

>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.6   0.1   2.2e-07   0.00057      12      38 .]      14      45 ..       4      45 .. 0.79
   2 !   24.0   0.0     2e-08     5e-05       3      37 ..      63      98 ..      61      99 .. 0.87
   3 !   15.6   1.8   8.8e-06     0.022       2      38 .]     123     160 ..     122     160 .. 0.92
   4 !   24.9   0.0     1e-08   2.6e-05       2      37 ..     165     201 ..     164     202 .. 0.94
   5 ?    0.0   6.3      0.73   1.9e+03       4      37 ..     299     324 ..     227     324 .. 0.73
   6 !    8.5   0.1    0.0016         4      13      34 ..     343     364 ..     334     365 .. 0.84
   7 ?    5.6   0.1     0.012        32      18      37 ..     712     739 ..     687     740 .. 0.72

  Alignments for each domain:
  == domain 1  score: 20.6 bits;  conditional E-value: 2.2e-07
                S.....EEEEEEETTSSEEEEE.ETTSEEEEEE CS
        WD40 12 s.....vtslafspdgawlasG.sdDgtvriWd 38
                      v+s+++spdg+ l+++ + Dg vriW+
  EEA20632.1 14 ErkdfeVYSCDVSPDGKRLVTAaG-DGYVRIWS 45
                134477*************98736.*******5 PP

  == domain 2  score: 24.0 bits;  conditional E-value: 2e-08
                EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40  3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37
                +l + + H + ++ ++fsp+g++lasG dD+ v ++
  EEA20632.1 63 QLASMSNHsGTIHTVRFSPNGKYLASGADDKIVCVY 98
                5778889*555**********************998 PP

  == domain 3  score: 15.6 bits;  conditional E-value: 8.8e-06
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +++r l GH ++v +l +s d++ l+s + D +v +W+
  EEA20632.1 123 RTIRRLIGHdNDVQDLGWSYDSSILVSVGLDSKVVVWS 160
                 6788999**999**************9899*******5 PP

  == domain 4  score: 24.9 bits;  conditional E-value: 1e-08
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 
                 ++l+tl+ H s+v ++ f+p ++++a++sdD+tv+i+
  EEA20632.1 165 EKLKTLSVHqSHVKGITFDPANKYFATASDDRTVKIF 201
                 6799*****999***********************97 PP

  == domain 5  score: 0.0 bits;  conditional E-value: 0.73
                 EEEEESSSSEEEEEEETTSSE...EE.EEETTSEEEEE CS
        WD40   4 lrtltGHssvtslafspdgaw...la.sGsdDgtvriW 37 
                 +++ + H           +++   +a +G+ D+++ +W
  EEA20632.1 299 VKSGSEH-----------HNLvtvIAcAGG-DKSLSVW 324
                 2233333...........333222442567.9999999 PP

  == domain 6  score: 8.5 bits;  conditional E-value: 0.0016
                 EEEEEEETTSSEEEEEETTSEE CS
        WD40  13 vtslafspdgawlasGsdDgtv 34 
                  ++la+spdg+ l++   Dgt+
  EEA20632.1 343 LSDLAWSPDGTCLFATALDGTI 364
                 67999*******987667**98 PP

  == domain 7  score: 5.6 bits;  conditional E-value: 0.012
                 EETTSSEEEEE..E.T.....TSEEEEE CS
        WD40  18 fspdgawlasG..s.d.....DgtvriW 37 
                 f p + +la+G  + +     Dg+++iW
  EEA20632.1 712 FLPKSVLLATGntGfWsvaceDGSIYIW 739
                 666666777653312133334******* PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.0   0.00053       1.4      29      68 ..       7      47 ..       4      60 .. 0.88
   2 !   11.1   0.0   0.00014      0.36      35      83 ..      68     116 ..      61     125 .. 0.85
   3 !   11.0   0.2   0.00016       0.4      27      89 ..     123     182 ..     119     185 .. 0.86
   4 !    5.3   0.0    0.0093        24      34      68 ..     170     204 ..     154     214 .. 0.82
   5 ?    2.3   0.0      0.08   2.1e+02       3      57 ..     182     254 ..     180     267 .. 0.67
   6 !    9.5   0.0   0.00046       1.2      33      76 ..     335     378 ..     310     392 .. 0.77
   7 ?   -3.3   0.0       4.7   1.2e+04      55      73 ..     729     747 ..     725     759 .. 0.64

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00053
  ANAPC4_WD40 29 vwtl.eedkedsevrsLaWkpdgklLavaysdgevrlldae 68
                 vw +   + +d ev s   +pdgk L+ a  dg vr+ + e
   EEA20632.1  7 VWLThGGERKDFEVYSCDVSPDGKRLVTAAGDGYVRIWSTE 47
                 6666566789999************************9987 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00014
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvkseka 83 
                  ++++++++ ++++p+gk La + +d  v +++       h+ + +s++a
   EEA20632.1  68 SNHSGTIHTVRFSPNGKYLASGADDKIVCVYSLDANPPSHTTTFGSDEA 116
                  688999**************************99999999988888765 PP

  == domain 3  score: 11.0 bits;  conditional E-value: 0.00016
  ANAPC4_WD40  27 qrvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                  + +  l   ++d+ v++L W+ d ++L+ +  d++v + + ++ + +++lsv++++ v+ +++
   EEA20632.1 123 RTIRRL--IGHDNDVQDLGWSYDSSILVSVGLDSKVVVWSGHTFEKLKTLSVHQSH-VKGITF 182
                  555555..57899***************************************9995.777665 PP

  == domain 4  score: 5.3 bits;  conditional E-value: 0.0093
  ANAPC4_WD40  34 edkedsevrsLaWkpdgklLavaysdgevrlldae 68 
                   + ++s+v+++ + p +k +a a +d +v+++  +
   EEA20632.1 170 LSVHQSHVKGITFDPANKYFATASDDRTVKIFRFN 204
                  4678999***********************99765 PP

  == domain 5  score: 2.3 bits;  conditional E-value: 0.08
  ANAPC4_WD40   3 wcptmDLiAlatedgellvfRlng..................qrvwtleedkedsevrsLaWkpdgklLavay 57 
                  + p +  +A a++d  + +fR+n                   + v  ++++      r  +W+pdg  +a a 
   EEA20632.1 182 FDPANKYFATASDDRTVKIFRFNSpapnstahdqlnnfvletNIVTPFQSSPLTAYFRRCSWSPDGLHIAAAN 254
                  5566677889999999999999987777777766664444433333336666777777888888887777665 PP

  == domain 6  score: 9.5 bits;  conditional E-value: 0.00046
  ANAPC4_WD40  33 eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhsl 76 
                  ++d + ++ ++LaW+pdg+ L     dg++  +  e++++   +
   EEA20632.1 335 AQDISAKSLSDLAWSPDGTCLFATALDGTILAVRFEQAELGYPM 378
                  5677788899********************99999988876555 PP

  == domain 7  score: -3.3 bits;  conditional E-value: 4.7
  ANAPC4_WD40  55 vaysdgevrlldaesgkvv 73 
                  va++dg++ +      +++
   EEA20632.1 729 VACEDGSIYIWTPAGRRLI 747
                  7888888877655444444 PP

>> HIRA_B  HIRA B motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.6   0.1   1.3e-13   3.3e-10       1      21 [.     497     517 ..     497     519 .. 0.95

  Alignments for each domain:
  == domain 1  score: 39.6 bits;  conditional E-value: 1.3e-13
      HIRA_B   1 KQkvTitKdGKKRVaPtLiSs 21 
                 KQ++T+tKdGKKR+aP+L+S 
  EEA20632.1 497 KQRPTYTKDGKKRIAPLLVSG 517
                 9******************96 PP

>> PD40  WD40-like Beta Propeller Repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0      0.03        76      16      24 ..      25      33 ..      25      44 .. 0.91
   2 !   10.6   0.0   0.00017      0.44       4      24 ..      67      87 ..      64      87 .. 0.92
   3 ?    3.1   0.0     0.037        96      15      24 ..     242     251 ..     241     251 .. 0.84
   4 ?    2.8   0.1     0.046   1.2e+02      15      21 ..     347     353 ..     344     356 .. 0.87
   5 ?   -1.1   0.0      0.76   1.9e+03      14      22 ..     500     508 ..     499     508 .. 0.91

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.03
                E-TTSSEEE CS
        PD40 16 fSPDGkrla 24
                +SPDGkrl+
  EEA20632.1 25 VSPDGKRLV 33
                5******97 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00017
                --SSSS.EEEEEE-TTSSEEE CS
        PD40  4 ltntpgnegaPsfSPDGkrla 24
                + n++g ++  +fSP+Gk+la
  EEA20632.1 67 MSNHSGTIHTVRFSPNGKYLA 87
                78*****************97 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.037
                 EE-TTSSEEE CS
        PD40  15 sfSPDGkrla 24 
                 s+SPDG  +a
  EEA20632.1 242 SWSPDGLHIA 251
                 8*****7765 PP

  == domain 4  score: 2.8 bits;  conditional E-value: 0.046
                 EE-TTSS CS
        PD40  15 sfSPDGk 21 
                 ++SPDG+
  EEA20632.1 347 AWSPDGT 353
                 8*****7 PP

  == domain 5  score: -1.1 bits;  conditional E-value: 0.76
                 EEE-TTSSE CS
        PD40  14 PsfSPDGkr 22 
                 P++++DGk+
  EEA20632.1 500 PTYTKDGKK 508
                 9******96 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.5   0.0    0.0014       3.5     189     215 ..      19      45 ..      13      58 .. 0.84
   2 ?    3.5   0.0     0.011        29     176     219 ..      59     103 ..      46     180 .. 0.62
   3 ?   -0.7   0.0      0.21   5.4e+02     186     216 ..     173     203 ..     163     209 .. 0.85
   4 !    5.2   0.0    0.0034       8.6     189     211 ..     342     364 ..     303     389 .. 0.78
   5 ?    0.1   0.0      0.12     3e+02     146     200 ..     766     823 ..     751     842 .. 0.71

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0014
    Ge1_WD40 189 liveaafspdGtalatasedGevkffq 215
                 ++ +  +spdG  l ta+ dG+v+ + 
  EEA20632.1  19 EVYSCDVSPDGKRLVTAAGDGYVRIWS 45 
                 5777889*****************996 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.011
    Ge1_WD40 176 eieegllkieehs.liveaafspdGtalatasedGevkffqvyle 219
                 ++ + l  +++hs +i +  fsp+G  la  + d +v  + +  +
  EEA20632.1  59 DKPKQLASMSNHSgTIHTVRFSPNGKYLASGADDKIVCVYSLDAN 103
                 555567788899889999****************99988876554 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 0.21
    Ge1_WD40 186 ehsliveaafspdGtalatasedGevkffqv 216
                 ++s++   +f p     atas d +vk f+ 
  EEA20632.1 173 HQSHVKGITFDPANKYFATASDDRTVKIFRF 203
                 34688899999****************9975 PP

  == domain 4  score: 5.2 bits;  conditional E-value: 0.0034
    Ge1_WD40 189 liveaafspdGtalatasedGev 211
                  +++ a+spdGt l +++ dG++
  EEA20632.1 342 SLSDLAWSPDGTCLFATALDGTI 364
                 68999****************85 PP

  == domain 5  score: 0.1 bits;  conditional E-value: 0.12
    Ge1_WD40 146 llvltrgdkaeiwsvdmiaskygsgelsveeieegllkieeh..s.liveaafspdGt 200
                 ll +t      +w+v++++s +   +l++     + ++  +   +  i+ a + ++G 
  EEA20632.1 766 LLCITAVGMCYVWNVKTVSSPHPPVSLQPVLDAATHVQTGQAilApAITGARINSEGR 823
                 6677777788889999999999888888876666666665553312567776666665 PP

>> IKI3  IKI3 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.0   0.00013      0.32     302     393 ..     130     215 ..     123     234 .. 0.76

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00013
                 XXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXX CS
        IKI3 302 keeeevqsLaWsadSevLav.rledrvqlwtisNyhWYLKqelrysasegveevkWdpekpltLlvltesgkievvdfafetavsetssendv 393
                  +++ vq+L Ws dS++L    l  +v +w     h + K ++   ++++v+ + +dp +++ +  ++ ++++++++f     +s+ +   d+
  EEA20632.1 130 GHDNDVQDLGWSYDSSILVSvGLDSKVVVWSG---HTFEKLKTLSVHQSHVKGITFDPANKY-FATASDDRTVKIFRFNSPAPNSTAH---DQ 215
                 568899************98466777****98...888888877778888899*****9988.7777777889998887766666433...44 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1068 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       729  (0.0406604); expected 358.6 (0.02)
Passed bias filter:                      543  (0.0302861); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.83u 0.31s 00:00:01.13 Elapsed: 00:00:00.47
# Mc/sec: 6855.08
//
Query:       EEA20633.1  [L=233]
Description: hypothetical protein PMAA_044620 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0039   16.9   0.0      0.005   16.6   0.0    1.1  1  MIP       Major intrinsic protein


Domain annotation for each model (and alignments):
>> MIP  Major intrinsic protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   2.8e-07     0.005     183     227 .]     132     186 ..     107     186 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 2.8e-07
                 HHHHHST-SSHHHHHHHHHHHTH........STTTTHH..HHHHHHHHHHHHHHH CS
         MIP 183 gipltGaamNpArslgpavvlnk........fedhwvy..lvGPliGailgalvY 227
                 ++  tGa  Np r++gp+++l +         + +w y  +   l G  +g+++Y
  EEA20633.1 132 TVWSTGAVFNPSRDFGPRLALLAlgygrqlfTNPYWFYgpFATSLTGCFMGGFLY 186
                 5678*****************9999999995445665522555567888888887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (233 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       530  (0.029561); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.24s 00:00:00.67 Elapsed: 00:00:00.40
# Mc/sec: 1742.34
//
Query:       EEA20634.1  [L=352]
Description: S-adenosylmethionine-dependent methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.4e-15   57.4   0.0    3.8e-08   33.2   0.0    2.3  2  Methyltransf_31  Methyltransferase domain
    3.7e-09   36.6   1.3    2.2e-08   34.1   1.3    2.1  1  Methyltransf_23  Methyltransferase domain
      7e-07   29.9   0.0      9e-06   26.3   0.0    2.3  2  Methyltransf_25  Methyltransferase domain
    7.8e-06   26.5   0.0    0.00082   20.0   0.0    2.7  2  Methyltransf_11  Methyltransferase domain
    6.1e-05   23.7   2.3     0.0013   19.5   0.4    2.8  2  Methyltransf_12  Methyltransferase domain
    0.00063   18.3  11.6    0.00085   17.9  11.6    1.1  1  SGT1             SGT1 protein
    0.00072   19.6   1.8      0.001   19.1   0.1    1.9  2  Methyltransf_32  Methyltransferase domain
     0.0014   18.8   0.0      0.056   13.5   0.0    2.1  1  FtsJ             FtsJ-like methyltransferase
     0.0069   16.7   6.9     0.0069   16.7   6.9    2.3  2  RNA_pol_3_Rpc31  DNA-directed RNA polymerase III subunit Rpc3
  ------ inclusion threshold ------
      0.013   14.8  14.5      0.013   14.8  14.5    2.1  2  NOA36            NOA36 protein
      0.019   14.5   0.0      0.038   13.5   0.0    1.5  1  MTS              Methyltransferase small domain
      0.027   14.5  16.3       0.53   10.3   6.3    2.3  2  RXT2_N           RXT2-like, N-terminal
      0.028   14.0   0.2      0.056   13.0   0.1    1.5  1  MetW             Methionine biosynthesis protein MetW
      0.042   13.2   0.0       0.12   11.7   0.0    1.8  1  PrmA             Ribosomal protein L11 methyltransferase (Prm
      0.043   14.2  37.5      0.062   13.7   2.0    2.4  2  CENP-B_dimeris   Centromere protein B dimerisation domain
       0.13   12.0   0.0        0.2   11.4   0.0    1.2  1  PCMT             Protein-L-isoaspartate(D-aspartate) O-methyl
       0.38   11.0  17.3        3.7    7.8  10.0    2.3  2  PTPRCAP          Protein tyrosine phosphatase receptor type C
       0.46    8.6  22.6      0.094   10.9  11.4    2.0  2  Nop14            Nop14-like family
       0.74   10.3   3.6       0.37   11.3   0.9    1.8  2  Usp              Universal stress protein family
        3.4    8.6  27.6        1.6    9.7   4.8    2.7  2  WRNPLPNID        Putative WW-binding domain and destruction b
        6.1    6.6  21.2       0.39   10.6   8.8    2.2  2  Myc_N            Myc amino-terminal region
        7.9    6.2  13.5        1.6    8.5   4.8    2.2  2  TFB6             Subunit 11 of the general transcription fact
        8.1    7.2  26.3        4.6    8.0   3.3    2.4  2  FYDLN_acid       Protein of unknown function (FYDLN_acid)
        8.7    4.3  31.5        2.9    5.9   1.9    2.1  2  DNA_pol_phi      DNA polymerase phi


Domain annotation for each model (and alignments):
>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.2   0.0   5.1e-11   3.8e-08       2      49 ..     105     151 ..     104     159 .. 0.90
   2 !   21.9   0.0   1.6e-07   0.00012      72     127 ..     236     318 ..     203     340 .. 0.75

  Alignments for each domain:
  == domain 1  score: 33.2 bits;  conditional E-value: 5.1e-11
  Methyltransf_31   2 dkglrvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielArenaq 49 
                      +k+ ++lDlG+G+G  +  l ++ g+k+ +vG+D+se++++lAre  q
       EEA20634.1 105 NKEPSILDLGTGNGSMLALLRKRGGFKGVMVGVDYSEQSVRLAREL-Q 151
                      67889***************************************94.3 PP

  == domain 2  score: 21.9 bits;  conditional E-value: 1.6e-07
  Methyltransf_31  72 d..............ekfDlilsnevlnaladpdkile............eiervlkpggilliedpr.llaelpakveeesk 127
                                     + fD++l++++++a++ +d++ +             ++++++pgg+l++++++ +++el + ++ es+
       EEA20634.1 236 NnndtkklswfpyetQGFDIVLDKGTFDAISLSDETTGsanthichqypiVASKLVRPGGYLIVTSCNwTEDELVHWLTTEST 318
                      444455555555555********************99999**********99****************545555444444444 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.1   1.3     3e-11   2.2e-08      18     131 ..     102     311 ..      79     332 .. 0.59

  Alignments for each domain:
  == domain 1  score: 34.1 bits;  conditional E-value: 3e-11
  Methyltransf_23  18 pklraggrvLdiGcGtGillevlren.gf..svtgvDlspeaveiae......................................kakkaqkdq 70 
                      +++++  ++Ld+G+G G++l +lr++ gf   ++gvD s++ v +a+                                      +        
       EEA20634.1 102 QRENKEPSILDLGTGNGSMLALLRKRgGFkgVMVGVDYSEQSVRLARelqrlrlhsayesgddsddydddddddddddeeeeeeeE-------- 187
                      2356666****************99966778899*********************9999999988886654332222222222220........ PP

  Methyltransf_23  71 fdeqeaaepqg........................................................................kfdlIvlre.v 91 
                                +                                                                        +fd I+l++ +
       EEA20634.1 188 ----------DeeeedvvvatstgddsvqreegiplknqdiqfeewdildpanetilnnnndtkklswfpyetqgfdivldkgTFDAISLSDeT 271
                      ..........122233333333334444444444444444444444444444466666666666666666666666666666699999888524 PP

  Methyltransf_23  92 lehvpd..ppellrqiatllkpgGylllseplaslkedrlll 131
                      +++      + +   + +l++pgGyl+++  +  + ed+l++
       EEA20634.1 272 TGSANThiCHQYPIVASKLVRPGGYLIVTSCN--WTEDELVH 311
                      55554322334444455566688888777663..44555544 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.3   0.0   1.2e-08     9e-06       1      42 [.     110     152 ..     110     174 .. 0.84
   2 ?    1.1   0.0      0.91   6.8e+02      58      78 ..     246     266 ..     215     295 .. 0.63

  Alignments for each domain:
  == domain 1  score: 26.3 bits;  conditional E-value: 1.2e-08
                      EEEET-TTSHHHHHHHCTST.SSEEEEEESSHHHHHHHHHHHH CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlg.kakvtgvDiseemleaarerae 42 
                      +LdlG+G+G +++ l kr+g k+ ++gvD+se+ ++ are  +
       EEA20634.1 110 ILDLGTGNGSMLALLRKRGGfKGVMVGVDYSEQSVRLARELQR 152
                      8*****************9889*****************9773 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.91
                      BSSSTTTEEEEEEESTGGGSS CS
  Methyltransf_25  58 lpfedgsfDlvvssgalhhls 78 
                      +p+e + fD+v+  g++  +s
       EEA20634.1 246 FPYETQGFDIVLDKGTFDAIS 266
                      455666666666554455443 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   0.0   1.1e-06   0.00082       1      41 [.     111     154 ..     111     171 .. 0.87
   2 ?    3.5   0.0      0.15   1.1e+02      49      96 .]     249     299 ..     225     299 .. 0.54

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 1.1e-06
                      EEET-TTSHHHHHHHHTT...SEEEEEES-HHHHHHHHHHCCHH CS
  Methyltransf_11   1 LdvGcGtGrlaealakrg...arvvgvDlskemlklakekasee 41 
                      Ld+G+G+G++++ l krg   +  vgvD+s++ ++la+e ++ +
       EEA20634.1 111 LDLGTGNGSMLALLRKRGgfkGVMVGVDYSEQSVRLARELQRLR 154
                      8**************9999*9****************9987765 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.15
                      TEECCCTSS-TT-EEEEEEES-CCC-...CCHHHHHHHHHHHEEEEEEEEE CS
  Methyltransf_11  49 vadaeklpfednsfDlvvssevlhhv...edpekalkeiaRvLkpgGllvi 96 
                      +    ++ + +++fD++ +s   +     +  +++   + ++++pgG+l++
       EEA20634.1 249 ETQGFDIVLDKGTFDAISLSDETTGSantHICHQYPIVASKLVRPGGYLIV 299
                      333344556666666666666333332333345555567788889998875 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.4   1.7e-06    0.0013       1      73 [.     111     198 ..     111     202 .. 0.67
   2 ?    3.0   0.0      0.23   1.7e+02      64      80 ..     231     269 ..     205     297 .. 0.61

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 1.7e-06
  Methyltransf_12   1 LeiGcGtGsllralleklpdieyt.gvDispsai......edakeklakrennnnnnvelealdlldldgg........ssfDlvvas 73 
                      L++G+G+Gs+l+ l+++  ++ +  gvD+s++++      ++ + + a +++++ + ++ +++d++d+d++        +  D+vva 
       EEA20634.1 111 LDLGTGNGSMLALLRKRGGFKGVMvGVDYSEQSVrlarelQRLRLHSAYESGDDSDDYDDDDDDDDDDDEEeeeeeedeEEEDVVVAT 198
                      8*****************8888877*********554432223333333333444444444444444444488888888888888876 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.23
  Methyltransf_12  64 g...................ssfDlvvasnvlhhl...k 80 
                      +                   + fD+v+  +++ ++   +
       EEA20634.1 231 EtilnnnndtkklswfpyetQGFDIVLDKGTFDAIslsD 269
                      233333333444456777888999999888888875541 PP

>> SGT1  SGT1 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9  11.6   1.1e-06   0.00085     349     516 ..      21     192 ..      12     209 .. 0.63

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 1.1e-06
        SGT1 349 eeyfkqsvass.sssasspgeeilelLksaleleleelkkeeeelppeddd...sWLe..iseeeLdkllqeragekelv...eesskeeeasydleev 438
                 e+y+++s ++  s++++++  +i++  +s    + ee ++ee e + +ddd   sW++    ++++ + l  r+ + + +   ++++++e +  dl   
  EEA20634.1  21 ETYYERSLEHIaSKTKTRTKPDITTTTTS---SNEEEDENEEGEEEDDDDDpgtSWFSehDAPQKVLRYLTSRKFPLAPKnlrKQRENKEPSILDLGTG 116
                 67888888775455555555556555533...44444444444445555556668*9722467888888888886655554446666666677899999 PP

        SGT1 439 tksmkaFldkvSsheGaelPeskeekevsfdvdsflkalekllgskieeeldsddldedssedsdeedeedeeeeeae 516
                   sm a l k  +++G+ +  + +e++v++  +     l++  +s   +++d+ d d+d+++d+dee+ee+ee+ee+e
  EEA20634.1 117 NGSMLALLRKRGGFKGVMVGVDYSEQSVRLARELQRLRLHSAYESG--DDSDDYDDDDDDDDDDDEEEEEEEEDEEEE 192
                 99*******************************9999999999887..443332223233333333333333222221 PP

>> Methyltransf_32  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.3       2.1   1.6e+03      78     112 ..      24      58 ..      13      68 .. 0.50
   2 !   19.1   0.1   1.4e-06     0.001      21     122 ..     102     197 ..      93     203 .. 0.69

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 2.1
  Methyltransf_32  78 fnkrlsfaelsieeatssktltkkveaeeekeeqe 112
                      ++++l+ +  +++++t+++ +t++++++ee++e+e
       EEA20634.1  24 YERSLEHIASKTKTRTKPDITTTTTSSNEEEDENE 58 
                      45555555555555555554444333333333222 PP

  == domain 2  score: 19.1 bits;  conditional E-value: 1.4e-06
  Methyltransf_32  21 akesgaltvvDvGaGkgYLsfvlalkekeyklkvvgidakeelvekaekrae.klgkkfnkrlsfaelsieeatssktltkkveaeeekeeqee 113
                      ++e+++ +++D+G G+g +   l   +  +k  +vg+d +e+ v+ a+++++ +l++++++     + + ++       ++  ++eee+ee+e+
       EEA20634.1 102 QRENKEPSILDLGTGNGSMLALLRK-RGGFKGVMVGVDYSEQSVRLARELQRlRLHSAYESGDDSDDYDDDD------DDDDDDDEEEEEEEED 188
                      578999**********988777777.4459**************9999987636666663333333332222......2333445666666666 PP

  Methyltransf_32 114 kesvdvlig 122
                      +e+ dv+++
       EEA20634.1 189 EEEEDVVVA 197
                      666676665 PP

>> FtsJ  FtsJ-like methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.0   7.5e-05     0.056      24     139 ..     109     305 ..      88     320 .. 0.65

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 7.5e-05
                 EEEECT-TTSHHHHHHCCT.T.-SEEEEEESSSS.....HHHTTEEEE........CS-CCCSSHHHHHCHCHHH........................ CS
        FtsJ  24 tvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm.....aplpgvtti........qgditdpetiekikealse........................ 85 
                  ++Dlg + G+    l +r g kg++v+vD  +      + l++++++          d  d +  +   +  +e                        
  EEA20634.1 109 SILDLGTGNGSMLALLRKRGGFKGVMVGVDYSEQsvrlaRELQRLRLHsayesgddSDDYDDDDDDDDDDDEEEEeeeedeeeedvvvatstgddsvqr 207
                 489999999999999988865567777777755544443222333333445544442222222222211111111334455556666666666666666 PP

                 ...........................................SSEEEEEE--S-S.S-CHHHHHHHHHCCCCHHHHCCHCCCCECCCEEEECCCHCC CS
        FtsJ  86 ...........................................rkvdlvvsDgapd.vsgvhdldeylqsqLllaalelalkllkpggtfvlkifrge 139
                                                            +++d+v+  g +d +s+  ++    + +++ +   +a+kl++pgg +++  ++ +
  EEA20634.1 208 eegiplknqdiqfeewdildpanetilnnnndtkklswfpyetQGFDIVLDKGTFDaISLSDETTGSANTHICHQYPIVASKLVRPGGYLIVTSCNWT 305
                 666666666666666666666666666667778999999999999*******9976157777777777789*****************9998877644 PP

>> RNA_pol_3_Rpc31  DNA-directed RNA polymerase III subunit Rpc31
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   6.5     0.058        43     187     211 ..      46      68 ..      12      78 .. 0.53
   2 !   16.7   6.9   9.2e-06    0.0069     173     211 ..     152     192 ..      80     199 .. 0.58

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.058
  RNA_pol_3_Rpc31 187 kkekedeeeeeeeeeddefdddded 211
                      +++  +eee+e +ee +e dddd d
       EEA20634.1  46 TTTSSNEEEDE-NEEGEEEDDDD-D 68 
                      22223333333.33344444333.3 PP

  == domain 2  score: 16.7 bits;  conditional E-value: 9.2e-06
  RNA_pol_3_Rpc31 173 klk.....elaeeeddeeekkekedeeeeeeeeeddefdddded 211
                      +l      e  ++ dd    ++ +d++++++eee++e +d++e+
       EEA20634.1 152 RLRlhsayESGDDSDD---YDDDDDDDDDDDEEEEEEEEDEEEE 192
                      3335443332333333...3333333333323334444433332 PP

>> NOA36  NOA36 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   5.1     0.016        12     270     292 ..      45      67 ..       9      81 .. 0.44
   2 ?   14.8  14.5   1.8e-05     0.013     262     296 ..     158     192 ..     131     201 .. 0.58

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.016
       NOA36 270 ddegdedddddddeedddeeedd 292
                 + ++++++++d++ee ++e++dd
  EEA20634.1  45 TTTTSSNEEEDENEEGEEEDDDD 67 
                 11112222222222211111111 PP

  == domain 2  score: 14.8 bits;  conditional E-value: 1.8e-05
       NOA36 262 alasgddeddegdedddddddeedddeeeddedee 296
                 a+ sgdd+dd+ d+ddddddd+e+++eee+de+ee
  EEA20634.1 158 AYESGDDSDDYDDDDDDDDDDDEEEEEEEEDEEEE 192
                 34444444444444444444444444444444443 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   5.1e-05     0.038      30      73 ..     105     149 ..      95     173 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 5.1e-05
                 CTCSEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHH CS
         MTS  30 elsgkvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesake 73 
                 +++ ++lDlG+G+G + a l k+      ++ vd + +++++a+e
  EEA20634.1 105 NKEPSILDLGTGNGSMLALLRKRGGFKGvMVGVDYSEQSVRLARE 149
                 25566*********999999888877665888**********997 PP

>> RXT2_N  RXT2-like, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   2.4    0.0011      0.85      40      80 ..      30      69 ..       7      86 .. 0.59
   2 ?   10.3   6.3   0.00071      0.53      55      87 ..     156     190 ..     124     218 .. 0.55

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0011
      RXT2_N 40 kilsrnpierskrkk...kekekeekeeeeedeegdeededddd 80
                +i s+ ++++    k   ++++++++eee+e+eeg+eed+ddd 
  EEA20634.1 30 HIASKTKTRT----KpdiTTTTTSSNEEEDENEEGEEEDDDDDP 69
                3333222222....233455666666777777777777766665 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00071
      RXT2_N  55 kekekeekeeeeedeegdeededdddee..eaeaa 87 
                 ++  ++ +++++ d+++d++d+dd++ee  e++++
  EEA20634.1 156 HSAYESGDDSDDYDDDDDDDDDDDEEEEeeEEDEE 190
                 33333333333333333333333333222122222 PP

>> MetW  Methionine biosynthesis protein MetW
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.1   7.5e-05     0.056      16      50 ..     109     145 ..     101     172 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 7.5e-05
        MetW  16 rvldlGcGdGellellkeekqvdgr..Gleldeegva 50 
                  +ldlG+G+G++l ll+++ + +g   G++ +e++v 
  EEA20634.1 109 SILDLGTGNGSMLALLRKRGGFKGVmvGVDYSEQSVR 145
                 69****************9999885337777777664 PP

>> PrmA  Ribosomal protein L11 methyltransferase (PrmA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00016      0.12     159     202 ..     104     149 ..      93     198 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00016
        PrmA 159 vkegeevlDvGtGSG.iLaiaaakLgakkv.vavDiDevAvkvake 202
                  +++ ++lD+GtG G +La+  ++ g k v v+vD+ e++v+ a+e
  EEA20634.1 104 ENKEPSILDLGTGNGsMLALLRKRGGFKGVmVGVDYSEQSVRLARE 149
                 344559*******9878*********998747************98 PP

>> CENP-B_dimeris  Centromere protein B dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   2.0   8.3e-05     0.062      16      34 ..      50      68 ..      40      98 .. 0.50
   2 ?    5.5  27.9     0.029        22       6      44 ..     159     197 ..     155     206 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 8.3e-05
  CENP-B_dimeris 16 sdeeeeeeeedeededeed 34
                    s+eee+e+ee ee++d++d
      EEA20634.1 50 SNEEEDENEEGEEEDDDDD 68
                    3333333333333333322 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.029
  CENP-B_dimeris   6 leagedsesesdeeeeeeeedeededeeddedddevpvp 44 
                      e+g+ds+   d++++++++dee+e+ee+de++++v v 
      EEA20634.1 159 YESGDDSDDYDDDDDDDDDDDEEEEEEEEDEEEEDVVVA 197
                     699*****9999999988888888887777777666654 PP

>> PCMT  Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00027       0.2      74     116 ..     107     149 ..      97     167 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00027
                 T-EEEEES-TTSHHHHHHHHHHCTTCEEEEEESBHHHHHHHHH CS
        PCMT  74 garvLevGsGsGyltavlarlvgekgrvvsierikelveeakr 116
                   ++L++G+G G   a+l +  g kg +v+++++++ v+ a++
  EEA20634.1 107 EPSILDLGTGNGSMLALLRKRGGFKGVMVGVDYSEQSVRLARE 149
                 5689*******************************99988864 PP

>> PTPRCAP  Protein tyrosine phosphatase receptor type C-associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   0.7    0.0052       3.9      40      71 ..      48      79 ..      19     126 .. 0.68
   2 ?    7.8  10.0     0.005       3.7      38      76 ..     171     209 ..     136     241 .. 0.65

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0052
     PTPRCAP 40 dgeedeeeEdqedeedeeedsedleggeeeae 71
                  +++ee+E++e+ee+ ++d+  ++   e++ 
  EEA20634.1 48 TSSNEEEDENEEGEEEDDDDDPGTSWFSEHDA 79
                34445555555555555555444444444444 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.005
     PTPRCAP  38 aedgeedeeeEdqedeedeeedsedleggeeeaesqeee 76 
                  +d+++d++eE++e+eedeee+++ +  ++ +++ q+ee
  EEA20634.1 171 DDDDDDDDDEEEEEEEEDEEEEDVVVATSTGDDSVQREE 209
                 245555566666666777777767777666666665554 PP

>> Nop14  Nop14-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   3.3     0.017        13     373     395 ..      47      68 ..      10     114 .. 0.53
   2 ?   10.9  11.4   0.00013     0.094     364     414 ..     161     209 ..     126     260 .. 0.51

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.017
       Nop14 373 eeedeeeeedeeeeeeeeededd 395
                   +++eee+++ee+ eee+d+dd
  EEA20634.1  47 TTSSNEEEDENEEG-EEEDDDDD 68 
                 22222222222222.22222222 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00013
       Nop14 364 seseeeeeeeeedeeeeedeeeeeeeeededdlsdleseeeeeedeleeel 414
                 s++++++   ++d+++++d++eeeeeee++++++d     +  +d +++e+
  EEA20634.1 161 SGDDSDD--YDDDDDDDDDDDEEEEEEEEDEEEEDVVVATSTGDDSVQREE 209
                 1222111..111111111111111222222222222222333333333222 PP

>> Usp  Universal stress protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.1       6.1   4.5e+03      54      64 ..      52      62 ..      18     107 .. 0.66
   2 ?   11.3   0.9   0.00049      0.37       2      70 ..     130     192 ..     129     220 .. 0.53

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 6.1
                HHHHHHHHHHH CS
         Usp 54 aeeeeleleea 64
                +ee+e e+ e+
  EEA20634.1 52 EEEDENEEGEE 62
                22222222222 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00049
                 -SEEEEEE-SSHHHHHHHHHHHHHHHHCTSEEEEEEEEESSHCCCCCCCHHHHHHHHHHHHHHHHHHHH CS
         Usp   2 ykrIlVavDgseeskkAlewAlelakargaelillhvidprasgavsdadeeaeeeeleleeaeleada 70 
                 +k ++V+vD se+s ++++   +l  ++      ++ + ++++++ +d d++  ++e+e+ee+e e+++
  EEA20634.1 130 FKGVMVGVDYSEQSVRLARELQRLRLHS------AYESGDDSDDYDDDDDDDDDDDEEEEEEEEDEEEE 192
                 6789**********99999998875555......33333333333333333333333333333332221 PP

>> WRNPLPNID  Putative WW-binding domain and destruction box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   4.8    0.0021       1.6      37      66 ..      45      73 ..      25      74 .. 0.44
   2 ?    3.7  14.8      0.15   1.1e+02      17      61 ..     147     192 ..     145     196 .. 0.52

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0021
   WRNPLPNID 37 e.svdedeeaeeeeeeeeeeedeedsgfngW 66
                + + +++ee++e+ee eee+  ++d+   +W
  EEA20634.1 45 TtTTSSNEEEDENEEGEEED--DDDDPGTSW 73
                22334444444444444444..444333366 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.15
   WRNPLPNID  17 dleLeeLllldseaeessege.svdedeeaeeeeeeeeeeedeeds 61 
                  +eL+ L l+ + ++  + ++   d+d++++++eeeeeeeedee++
  EEA20634.1 147 ARELQRLRLHSAYESGDDSDDyDDDDDDDDDDDEEEEEEEEDEEEE 192
                 5699999987666444443333333333344444444444444443 PP

>> Myc_N  Myc amino-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   4.4      0.24   1.8e+02     228     253 ..      42      63 ..       9      69 .. 0.45
   2 ?   10.6   8.8   0.00052      0.39     221     262 ..     159     200 ..     135     224 .. 0.67

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.24
       Myc_N 228 alssseedvlsesdeeeeeeeeeeee 253
                 +++++++++++e+de+ee e    ee
  EEA20634.1  42 DITTTTTSSNEEEDENEEGE----EE 63 
                 22222222222222222222....22 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00052
       Myc_N 221 ssssdskalssseedvlsesdeeeeeeeeeeeeidVVtvekr 262
                  +s+d ++   +++d  +++deeeeeeee+eee dVV    +
  EEA20634.1 159 YESGDDSDDYDDDDDDDDDDDEEEEEEEEDEEEEDVVVATST 200
                 444455455556666666677777777777788888765443 PP

>> TFB6  Subunit 11 of the general transcription factor TFIIH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   1.4      0.12        89     118     149 ..      49      67 ..      25      92 .. 0.46
   2 ?    8.5   4.8    0.0021       1.6     103     146 ..     149     192 ..     127     211 .. 0.54

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.12
        TFB6 118 eeeeeeedeeededeeeeeeeeeeeeeeedee 149
                 +++e eede+e+ +            ee+d++
  EEA20634.1  49 SSNE-EEDENEEGE------------EEDDDD 67 
                 1111.111111111............111111 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0021
        TFB6 103 ertRvlvvevlereeeeeeeeedeeededeeeeeeeeeeeeeee 146
                 e  R+++ ++ e+ +++++ ++d+++d+d++eeeeeeee+eeee
  EEA20634.1 149 ELQRLRLHSAYESGDDSDDYDDDDDDDDDDDEEEEEEEEDEEEE 192
                 45566667777777655553433333333222222222211111 PP

>> FYDLN_acid  Protein of unknown function (FYDLN_acid)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   3.3    0.0062       4.6      50      88 ..      33      68 ..      13      84 .. 0.40
   2 ?    4.6  15.2     0.071        53      54     100 ..     160     204 ..     136     223 .. 0.41

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0062
  FYDLN_acid 50 eaeeakkkkeeeedeedeeeeedvsdedadeeeeedddd 88
                ++ ++++ k + ++++++ +ee++++e+ +ee+  dddd
  EEA20634.1 33 SKTKTRT-KPDITTTTTSSNEEEDENEEGEEED--DDDD 68
                2222211.1111222222222222222222221..2222 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.071
  FYDLN_acid  54 akkkkeeeedeedeeeeedvsdedadeeeeedddddvdleedddddv 100
                 ++ +++++ d++d++  +d++de+++eeee+++++dv +++   dd 
  EEA20634.1 160 ESGDDSDDYDDDDDD--DDDDDEEEEEEEEDEEEEDVVVATSTGDDS 204
                 211222222222222..222222222222222222343433333333 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   1.9    0.0039       2.9     626     659 ..      36      68 ..      24      93 .. 0.49
   2 ?    4.0  22.0     0.015        11     639     682 ..     163     193 ..     148     228 .. 0.47

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0039
  DNA_pol_phi 626 earenkegqaelfedededeeddeeeeeeddeed 659
                  ++r +++ +      ++e+e+++ee eeedd++d
   EEA20634.1  36 KTRTKPDITTTTT-SSNEEEDENEEGEEEDDDDD 68 
                  4444444444333.12222222222222222211 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.015
  DNA_pol_phi 639 edededeeddeeeeeeddeededseedddeeesdedeededded 682
                  +d+d++++dd++++++d             ee++e+eede++ed
   EEA20634.1 163 DDSDDYDDDDDDDDDDD-------------EEEEEEEEDEEEED 193
                  11222222222222222.............22222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (352 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1090  (0.0607954); expected 358.6 (0.02)
Passed bias filter:                      578  (0.0322383); expected 358.6 (0.02)
Passed Vit filter:                       130  (0.00725082); expected 17.9 (0.001)
Passed Fwd filter:                        79  (0.00440627); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              24  [number of targets reported over threshold]
# CPU time: 0.85u 0.32s 00:00:01.17 Elapsed: 00:00:00.49
# Mc/sec: 2148.94
//
Query:       EEA20635.1  [L=112]
Description: Yippee zinc-binding protein Moh1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.1e-17   63.2   0.1    2.3e-17   63.1   0.1    1.0  1  Yippee-Mis18  Yippee zinc-binding/DNA-binding /Mis18, centrom
  ------ inclusion threshold ------
       0.17   10.7   0.1       0.75    8.6   0.0    1.7  2  HECT_2        HECT-like Ubiquitin-conjugating enzyme (E2)-bin


Domain annotation for each model (and alignments):
>> Yippee-Mis18  Yippee zinc-binding/DNA-binding /Mis18, centromere assembly
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.1   0.1   2.6e-21   2.3e-17       2      91 ..      14     107 ..      13     112 .] 0.78

  Alignments for each domain:
  == domain 1  score: 63.1 bits;  conditional E-value: 2.6e-21
                   EEEETTTS-EEEECCCEEE......EECC......CEEEES---CCCEEEECEEEETTSTTEEEEEEEETTT--EEEEEEEECSCC.CCCCCTCEEE CS
  Yippee-Mis18   2 vfqCkkCktilgdslqlvs......egra......lnivvlkkvtrnvvvgkelvtdeegkctystlsCkgCnsvlGwkYksteee.lkykrglfil 85 
                   +f C++Ck++l+d +++vs      +g+a       n++  ++v+r++++g++ v+d         +sC++C  ++GwkY ++ e   kyk+g+fil
    EEA20635.1  14 IFGCRECKAHLADYNEIVSrnfrgqHGKAflfqtvVNVTEGDPVERSMTTGRHIVRD---------ISCRTCRVIVGWKYDKAYEPgEKYKEGKFIL 101
                   79*****************98844433335555555555555566666666666655.........******************************* PP

                   EGGGEE CS
  Yippee-Mis18  86 etkait 91 
                   e + ++
    EEA20635.1 102 EEALLC 107
                   *88766 PP

>> HECT_2  HECT-like Ubiquitin-conjugating enzyme (E2)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.1     0.011     1e+02     112     129 ..      12      29 ..       6      36 .. 0.76
   2 ?    8.6   0.0   8.4e-05      0.75     169     225 ..      27      83 ..      19      90 .. 0.80

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.011
      HECT_2 112 etslrCrsCknvllksrk 129
                 +  + Cr+Ck+ l + ++
  EEA20635.1  12 DKIFGCRECKAHLADYNE 29 
                 56689*****99988655 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 8.4e-05
      HECT_2 169 yga..snklspqegdglvdltsfllaesdcqglklseetkpkkeeslsCkrCkatlGee 225
                 y++  s +++ q+g+ ++  t + ++e d  +  ++  t ++  +++sC++C+ ++G +
  EEA20635.1  27 YNEivSRNFRGQHGKAFLFQTVVNVTEGDPVERSMT--TGRHIVRDISCRTCRVIVGWK 83 
                 555434488889999999999999999998887766..9******************75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (112 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       434  (0.0242066); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 794.20
//
Query:       EEA20636.1  [L=374]
Description: nicotinamide N-methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.5e-11   42.3   0.0      1e-10   41.7   0.0    1.2  1  Methyltransf_16  Lysine methyltransferase
  ------ inclusion threshold ------
      0.024   13.9   0.0      0.039   13.3   0.0    1.3  1  GidB             rRNA small subunit methyltransferase G
       0.14   12.0   0.0       0.24   11.2   0.0    1.4  1  Methyltransf_23  Methyltransferase domain


Domain annotation for each model (and alignments):
>> Methyltransf_16  Lysine methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.7   0.0   1.7e-14     1e-10      15     144 ..     132     274 ..     124     282 .. 0.81

  Alignments for each domain:
  == domain 1  score: 41.7 bits;  conditional E-value: 1.7e-14
  Methyltransf_16  15 esigrkvWdaavvlvkylekklake........lganelsklsvlELGsGtGlvGlavaellpeakviltDlee...llellkknielnkn.al 96 
                      +  ++ +W aa+v+++ +e + a e        +   ++++ +vlELG+G+Gl  ++ a++    +v++tD +     l  +++ni  n    l
       EEA20636.1 132 KLFAHFLWSAAMVVAQGVEDADALEksgskstdKTMWSVKGHRVLELGAGAGLPSIISALA-FASHVTITDHPSspaFLGAIEHNIIENVPaSL 224
                      5678899******9998887655556788877666678999***************99998.7889*****9874446788999*988776699 PP

  Methyltransf_16  97 kskvkvevLdWgeeleedlleke...evDlilaaDcvYledslelLvkvLk 144
                      + ++   + +Wg  le+d ++++   ++  i+aaDc+++ +  + L+k+L 
       EEA20636.1 225 RPNIDSAPHEWGV-LEDDQFAQKnkgTFTRIIAADCLWMLHQHSNLAKTLL 274
                      ***********98.7777776541225889******************996 PP

>> GidB  rRNA small subunit methyltransferase G
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   6.6e-06     0.039      47      73 ..     172     196 ..     163     216 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 6.6e-06
                 CCC-.EEEETSTTTTTHHHHHHH-TTS CS
        GidB  47 ekrdkviDvGsGaGlPGipLaiarpel 73 
                  +  +v+ +G+GaGlP+i+ a+a+++ 
  EEA20636.1 172 GH--RVLELGAGAGLPSIISALAFASH 196
                 33..49***************998764 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0     4e-05      0.24      21     112 ..     170     280 ..     140     283 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 4e-05
  Methyltransf_23  21 raggrvLdiGcGtGillevlrengf.svtgvDlspeaveiae.........................kakkaqkdqfdeqeaaepqgkfdlIvl 88 
                       +g rvL++G+G G  + + +  ++ +vt  D  +                                +    ++dqf    a++++g+f  I++
       EEA20636.1 170 VKGHRVLELGAGAGLPSIISALAFAsHVTITDHPSSPA---FlgaiehniienvpaslrpnidsaphEWGVLEDDQF----AQKNKGTFTRIIA 256
                      4566**********433333444445788888643222...133466877778888888877755555555555555....************* PP

  Methyltransf_23  89 revlehvpdppellrqiatllkpg 112
                       ++l  ++ +  l +++   l++g
       EEA20636.1 257 ADCLWMLHQHSNLAKTLLWFLSDG 280
                      ********9999999998888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (374 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       530  (0.029561); expected 358.6 (0.02)
Passed bias filter:                      425  (0.0237046); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.24s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 2692.50
//
Query:       EEA20637.1  [L=437]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
     0.0053   17.2   3.4      0.016   15.7   3.4    1.9  1  zf-C2H2    Zinc finger, C2H2 type
     0.0082   15.9   3.9     0.0082   15.9   3.9    2.8  3  PAP1       Transcription factor PAP1
  ------ inclusion threshold ------
      0.013   15.2   0.2      0.047   13.5   0.0    1.9  2  BING4CT    BING4CT (NUC141) domain
       0.21   12.5   3.3       0.59   11.1   3.3    1.8  1  zf-C2H2_4  C2H2-type zinc finger


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   3.4   3.5e-06     0.016       2      20 ..     135     153 ..     134     156 .. 0.94

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 3.5e-06
                 EETTTTEEESSHHHHHHHH CS
     zf-C2H2   2 kCpdCgksFkrksnLkrHi 20 
                 +C+ Cgk +k++s L++H+
  EEA20637.1 135 RCDQCGKGYKHSSCLTKHM 153
                 8*****************9 PP

>> PAP1  Transcription factor PAP1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   2.6      0.81   3.6e+03      96     149 ..      41      82 ..       4     121 .. 0.44
   2 !   15.9   3.9   1.8e-06    0.0082      56     157 ..     132     244 ..      83     251 .. 0.54
   3 ?    0.4   3.0     0.092   4.1e+02     132     205 ..     265     337 ..     247     363 .. 0.64

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 0.81
        PAP1  96 nysnsaanegltrgstassaesqsstysansgtstssdSPsssseshqgqlSSc 149
                 n+   +  + ++r  t+s +   +s +s   +   +++SP            S+
  EEA20637.1  41 NH-RVTRRKSMSRRGTESTSIGATSGFSSYLSRGIHAASPD-----------SI 82 
                 11.11112222222222222222222222222223333333...........33 PP

  == domain 2  score: 15.9 bits;  conditional E-value: 1.8e-06
        PAP1  56 P..............stsaststtssvesasasssesknqrsnslealtkednnnysnsaanegltrgstassaesqsstysansgtstssdSPsssse 140
                                s  +++ ++++ + a +s+   +++++ +l   +    + ++++a    +++  +a+ a  + +t s + ++ +ss+SP +ss+
  EEA20637.1 132 TelrcdqcgkgykhsSCLTKHMWEHNPAWAVTSKLLISKHQQVQLLEAATVLVAMNQETADA--AAEVTAAAAAAASMETESNEIESDNSSASPGASSD 228
                 15555555555554333333334444444444444444434444444433333333322222..2222222222222333344444556699******* PP

        PAP1 141 shqgqlSScgTSPEPst 157
                  h g  SS++T P P+ 
  EEA20637.1 229 MHDG-ISSVETTPPPMD 244
                 **88.9*******9975 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.092
        PAP1 132 sdSPsssseshqgqlSScgTSPEPstqSPaakksketsstieeeevahttidgeksfcekLglacgniknPiPa 205
                  + Ps+ s s q+  SS+      s +SPa ++ +++s      + ++t i+ e+s  + L+ a+   +  +P+
  EEA20637.1 265 FNHPSAFSRSYQSVASSS-YADNGSLHSPAFSHFRHSSIDTRPSTAETTGIHEEDSEASDLAAAIRLCNFGTPR 337
                 346888888888854444.4567888899888844444233344455566677777777777777666655555 PP

>> BING4CT  BING4CT (NUC141) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.1       1.1   4.9e+03      25      46 ..      59      80 ..      57      86 .. 0.72
   2 ?   13.5   0.0     1e-05     0.047      27      65 ..     359     400 ..     357     401 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 1.1
     BING4CT 25 gvghskgissiivPGsGepnfd 46
                ++g ++g+ss +  G   +  d
  EEA20637.1 59 SIGATSGFSSYLSRGIHAASPD 80
                68999***99886665555555 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 1e-05
     BING4CT  27 ghskgis...siivPGsGepnfdaleanpfetkkqrrereVr 65 
                 g+++gis   s+ vPGs  + f ++  +p ++ k   ereV+
  EEA20637.1 359 GQQSGISnagSLGVPGSTPAVFGSFSLDPSQSYKVSDEREVK 400
                 6677765333789****************************8 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   3.3   0.00013      0.59       2      23 ..     135     156 ..     134     157 .. 0.93

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00013
   zf-C2H2_4   2 kCpiCgksFsskkaLlrHlkth 23 
                 +C++Cgk ++ ++ L +H+  h
  EEA20637.1 135 RCDQCGKGYKHSSCLTKHMWEH 156
                 7*********9999*****988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (437 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       803  (0.0447878); expected 358.6 (0.02)
Passed bias filter:                      388  (0.0216409); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.48
# Mc/sec: 2757.04
//
Query:       EEA20638.1  [L=425]
Description: hypothetical protein PMAA_044670 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.062   13.3   0.6       0.17   11.9   0.6    1.7  1  DUF1932   Domain of unknown function (DUF1932)
       0.26   10.6  11.9       0.32   10.3  11.9    1.4  1  BUD22     BUD22


Domain annotation for each model (and alignments):
>> DUF1932  Domain of unknown function (DUF1932)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.6   1.9e-05      0.17       9      45 ..     374     410 ..     368     411 .. 0.95

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 1.9e-05
                 HHHHHHHHHSSTHHHHHHHHHHHHHHHHHHHHHHHHH CS
     DUF1932   9 elldeleeslpallaraergltgmppkAyRwveEMee 45 
                 e+l++l++  p++++  +r   +m ++ +R+ +EM+e
  EEA20638.1 374 EVLSSLQTESPQTDQPTRRRKNRMGQRQRRRLREMRE 410
                 79**********************************8 PP

>> BUD22  BUD22
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3  11.9   3.6e-05      0.32     305     333 ..     386     414 ..     180     425 .] 0.87

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 3.6e-05
       BUD22 305 daeesvapk..RKNRrGQrARraIwEK..KYGk 333
                  +   + p+  RKNR+GQr Rr + E   KYG 
  EEA20638.1 386 TD---Q-PTrrRKNRMGQRQRRRLREMreKYGW 414
                 22...2.3335***************8889996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (425 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       871  (0.0485805); expected 358.6 (0.02)
Passed bias filter:                      597  (0.033298); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.40
# Mc/sec: 3188.87
//
Query:       EEA20639.1  [L=193]
Description: 60S ribosomal protein L24b [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.5e-29  100.8   5.1    3.5e-29  100.8   5.1    1.9  2  Ribosomal_L24e  Ribosomal protein L24e


Domain annotation for each model (and alignments):
>> Ribosomal_L24e  Ribosomal protein L24e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.8   5.1     2e-33   3.5e-29       1      64 [.       1      64 [.       1      66 [. 0.98
   2 ?   -2.9   0.0      0.47   8.5e+03      33      48 ..     103     118 ..      99     120 .. 0.71

  Alignments for each domain:
  == domain 1  score: 100.8 bits;  conditional E-value: 2e-33
                    XXX-B-TTT-SB--SS--EEEE-TTS-EEEESSHHHHHHHHTT--GGGSTTSTTT-XXXXXXXX CS
  Ribosomal_L24e  1 mktekCsFsgykiyPGhGkrfvrnDgkvfrFlssKceklfkqkrnPrklkWTkayRrahkkelt 64
                    m++e CsF+++++yP++G++fvrnD+++frF++sKcek+fk+kr+Prk+kWTk+ R  ++ke+ 
      EEA20639.1  1 MRVEVCSFCSRPVYPSKGITFVRNDARSFRFCRSKCEKNFKMKRQPRKVKWTKTHRALRGKEMI 64
                    9************************************************************996 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.47
                     SHHHHHHHHTT--GGG CS
  Ribosomal_L24e  33 ssKceklfkqkrnPrk 48 
                     +++ e+ f +kr + k
      EEA20639.1 103 RQRRERVFTKKRLAGK 118
                     6677888888886665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (193 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1137  (0.0634168); expected 358.6 (0.02)
Passed bias filter:                      464  (0.0258799); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.41
# Mc/sec: 1419.19
//
Query:       EEA20640.1  [L=152]
Description: 60S ribosomal protein L24b [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    0.00015   21.9   0.9    0.00015   21.9   0.9    2.1  2  Ribosomal_L24e  Ribosomal protein L24e
  ------ inclusion threshold ------
       0.25   11.4   1.3       0.33   11.0   1.3    1.2  1  MCU             Mitochondrial calcium uniporter


Domain annotation for each model (and alignments):
>> Ribosomal_L24e  Ribosomal protein L24e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.9   0.9   1.6e-08   0.00015      42      64 ..       1      23 [.       1      25 [. 0.93
   2 ?   -2.4   0.1      0.65   5.8e+03      33      48 ..      62      77 ..      57      79 .. 0.72

  Alignments for each domain:
  == domain 1  score: 21.9 bits;  conditional E-value: 1.6e-08
                    TT--GGGSTTSTTT-XXXXXXXX CS
  Ribosomal_L24e 42 qkrnPrklkWTkayRrahkkelt 64
                    +kr+Prk+kWTk+ R  ++ke+ 
      EEA20640.1  1 MKRQPRKVKWTKTHRALRGKEMI 23
                    79******************996 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.65
                    SHHHHHHHHTT--GGG CS
  Ribosomal_L24e 33 ssKceklfkqkrnPrk 48
                    +++ e+ f +kr + k
      EEA20640.1 62 RQRRERVFTKKRLAGK 77
                    6677888888886665 PP

>> MCU  Mitochondrial calcium uniporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   1.3   3.6e-05      0.33      26      89 ..      32     121 ..      10     127 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 3.6e-05
                 X.................XXXXXXXXXXXXXXXXX-SS.........SSSSTSSSSSHHHHHHHHHHHHH-SHHHHHHHHTCCCGGGCHH CS
         MCU  26 e.................eeakvllrvkqlvkalesal.........nveeeqlkkereleekleelreelepleekkeeidekAerrtr 89 
                 +                  + k ++rv+++ ++ e+++           e+++++++r + + ++ +r+el++++e++  + ++Ae+++ 
  EEA20640.1  32 QfaqkrnvpvkydrnlvaATIKAMERVEEIRQRRERVFtkkrlagklARERQREEDRRVVAQGEHLIRKELREMQEQNVPLGASAEKEKA 121
                 2334444444455555555577777888877777777788888888666777777888888889999**********9999999998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (152 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1029  (0.0573931); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.47
# Mc/sec: 967.53
//
Query:       EEA20641.1  [L=105]
Description: mitochondrial DnaJ chaperone (Tim14), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-07   30.6   0.0    3.9e-07   30.1   0.0    1.3  1  Pam16     Pam16
    3.9e-05   23.7   0.1    6.5e-05   23.0   0.1    1.3  1  DnaJ      DnaJ domain


Domain annotation for each model (and alignments):
>> Pam16  Pam16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.1   0.0   4.3e-11   3.9e-07      55     110 ..      48     104 ..      20     105 .] 0.88

  Alignments for each domain:
  == domain 1  score: 30.1 bits;  conditional E-value: 4.3e-11
                 X-HHHHHHHHT--G.--SHHHHHHHHHHHHHHT-CCCTS-HHHHHHHHHHHHHHHHH CS
       Pam16  55 isleeslkilnvee.dlnreevekryehlfevndkskGGslylqskvfrakerldee 110
                 ++  e+  il+++e  l +++v k++  l+ +n  ++GGs yl +k+  ake ld+ 
  EEA20641.1  48 MTRREASLILELSErTLTKDKVRKNHRQLMLLNHPDRGGSPYLATKINEAKELLDKT 104
                 6778999*****9989*************************************9986 PP

>> DnaJ  DnaJ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.0   0.1   7.2e-09   6.5e-05       5      53 ..      56     101 ..      55     104 .. 0.80

  Alignments for each domain:
  == domain 1  score: 23.0 bits;  conditional E-value: 7.2e-09
                 HHTSSTTG.-HHHHHHHHHHHHHHHSTTTSCCHHHHHHHHHHHHHHHHHH CS
        DnaJ   5 iLgvskda.sedeIkkaYrklalkyHPDknpkdpeaeekFkeineAyevL 53 
                 iL++s+   ++d+++k++r+l+l  HPD+  ++p  +    +ineA e L
  EEA20641.1  56 ILELSERTlTKDKVRKNHRQLMLLNHPDRG-GSPYLA---TKINEAKELL 101
                 7888877549*******************9.777333...3588888877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (105 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       257  (0.0143343); expected 358.6 (0.02)
Passed bias filter:                      213  (0.0118802); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.36u 0.25s 00:00:00.61 Elapsed: 00:00:00.40
# Mc/sec: 780.06
//
Query:       EEA20642.1  [L=877]
Description: fungal specific transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.9e-24   83.8   0.0    2.6e-23   82.4   0.0    1.7  1  Fungal_trans  Fungal specific transcription factor domain
    8.9e-10   38.5  13.1    1.5e-09   37.8  13.1    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.4   0.0   2.9e-27   2.6e-23       4     266 ..     295     536 ..     293     537 .. 0.87

  Alignments for each domain:
  == domain 1  score: 82.4 bits;  conditional E-value: 2.9e-27
  Fungal_trans   4 ffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeili.....hedfsspssslwilq 95 
                   ff+nf+ ++p++h+p+f++     + s  +y  ++  ++i+++ a + + +  +   ++++++ +      ++  l      +++++  +++l ++q
    EEA20642.1 295 FFDNFNALLPLFHEPTFMHLV-ERQYSRDPYEGSGWWASINIVLAISHRLRVMSHLVPQEEDK-K------AWLYLKnamgvLTELTMRNTDLLSVQ 383
                   9********************.88888888888888888888877777777777777777755.2......4444445555599************* PP

  Fungal_trans  96 sLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddl 192
                   +Ll ++l+++++ +      ++  a+rl++s+gLh++ s  +      l + e e+r+R++w a+ lDk i+l  Grpp  dd+++n++LP +    
    EEA20642.1 384 ALLGMSLFLQGTPNPQPSFFLVAAAIRLSHSIGLHKRGSLFN------LNPVEVEQRKRVFWIAYLLDKDICLRSGRPPVQDDDDMNVELPSEIP-- 472
                   **************999999********************99......99999**************************99**********9987.. PP

  Fungal_trans 193 wesddaseetlvetklsneeksrkiasfllaLkkilskiagsllsiekqlqqrdlqseklswveeleraldnWr 266
                      d++  + lv       e +++i+  + +++ i+s +++ l+s +   q   +    l+ + el+r+l++W+
    EEA20642.1 473 --PDNVGIIPLVT-----GEGQVNIFRVMCRFAIIQSRVYKRLYSTKAAKQSDGEL---LNTIGELDRELEEWK 536
                   ..77777777776.....567888*****************999988877776666...99************8 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.8  13.1   1.6e-13   1.5e-09       1      39 [.      57      95 ..      57      96 .. 0.91

  Alignments for each domain:
  == domain 1  score: 37.8 bits;  conditional E-value: 1.6e-13
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfysesskr 39
                +aCd CrkkK+KCd+k P+Cs+C+ + +eC f +  +kr
  EEA20642.1 57 RACDMCRKKKIKCDGKMPKCSHCINYKTECIFTQVEKKR 95
                69*****************************77777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (877 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       592  (0.0330191); expected 358.6 (0.02)
Passed bias filter:                      414  (0.0230911); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.31s 00:00:00.96 Elapsed: 00:00:00.44
# Mc/sec: 5944.80
//
Query:       EEA20643.1  [L=898]
Description: mitochondrial inner membrane AAA protease Yta12, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.5e-69  231.6   0.0    1.2e-68  230.8   0.0    1.4  1  Peptidase_M41  Peptidase family M41
    4.3e-43  146.9   0.0    1.3e-42  145.3   0.0    1.9  1  AAA            ATPase family associated with various cellular
    1.1e-12   47.5   0.8    2.5e-12   46.4   0.2    1.9  2  AAA_lid_3      AAA+ lid domain
    2.3e-08   34.3   0.1    6.9e-08   32.8   0.1    1.8  1  FtsH_ext       FtsH Extracellular
    0.00054   20.0   0.0     0.0026   17.8   0.0    2.2  1  AAA_5          AAA domain (dynein-related subfamily)
      0.001   19.4   0.4       0.12   12.7   0.1    3.5  3  AAA_16         AAA ATPase domain
     0.0083   15.4   0.0      0.016   14.4   0.0    1.4  1  TIP49          TIP49 P-loop domain
     0.0096   16.2   0.3        1.2    9.4   0.1    3.3  3  AAA_22         AAA domain
  ------ inclusion threshold ------
      0.012   15.4   0.0      0.029   14.1   0.0    1.6  1  RuvB_N         Holliday junction DNA helicase RuvB P-loop dom
      0.014   15.5   0.1        4.1    7.6   0.0    2.9  2  YqzH           YqzH-like protein
       0.05   13.7   0.0       0.18   11.9   0.0    1.9  1  AAA_2          AAA domain (Cdc48 subfamily)
      0.059   13.1   0.1       0.24   11.1   0.1    2.0  2  IstB_IS21      IstB-like ATP binding protein
      0.091   13.2   0.0       0.25   11.8   0.0    1.8  1  AAA_17         AAA domain
       0.14   12.4   1.9        0.4   10.9   1.9    1.8  1  DUF2508        Protein of unknown function (DUF2508)


Domain annotation for each model (and alignments):
>> Peptidase_M41  Peptidase family M41
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  230.8   0.0   9.2e-72   1.2e-68       2     190 ..     671     851 ..     670     852 .. 0.97

  Alignments for each domain:
  == domain 1  score: 230.8 bits;  conditional E-value: 9.2e-72
                    X--HHHHHHHHHHHHHHHHHHCCSSS-S-B--EES--TTS.-----------TSS--BHHHHHHHHHHHHHHHHHHHHHHHS-BGGGHHHHHHHHH CS
  Peptidase_M41   2 visekekklvAyHEaGHalvglllkeadpveKvtiiPRgq.alGltlslPeedklsltkeellarlavllGGraaEelifgevttGasnDlekatk 96 
                    v+s +ek++vAyHEaGHa++g++lk adp+ Kv+iiPRgq alG++++lP+++++ +t ++l++r+a++lGGr++Eel+f++vt+Gas+D++k+t+
     EEA20643.1 671 VLSPEEKRTVAYHEAGHAICGWYLKWADPLLKVSIIPRGQgALGYAQYLPSSENYLMTVNQLMDRMAMTLGGRVSEELHFDTVTSGASDDFNKVTR 766
                    7899******************************************************************************************** PP

                    HHHHHHHTS---TTT-S--------..----.------SS-HHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHSEE-HHHHHH CS
  Peptidase_M41  97 iarkmvtefGmsdklGpvsleeeeeeevflgkelkkekelseetaeeideevkelveeayerakeileekreelealaeaLlekEtldaeeiee 190
                    +a +mvt+fGms+ +Gp+++ee+++ +         +k++seeta++id e++++v+eay+r++++l+ek++e+  +ae+Ll+kE+l+++++ +
     EEA20643.1 767 MASAMVTKFGMSKAIGPLHFEEDQQ-Q--------LHKPFSEETARNIDLEIRRIVDEAYKRCQDLLTEKKKEVGLVAEELLSKEVLSRDDMVR 851
                    ********************99887.2........479****************************************************9976 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.3   0.0     1e-45   1.3e-42       2     131 ..     455     587 ..     454     588 .. 0.96

  Alignments for each domain:
  == domain 1  score: 145.3 bits;  conditional E-value: 1e-45
                 EEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHH....TTCCCHHHHHHHHHHHHHHHHT CS
         AAA   2 llyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksr....sgseseeeervvnqLlteldgv 96 
                 +l+GppGtGKTllaka a e+gv+f+++sgse+++++vg +++++r+lf++a+++  p+i+fiDEida++ksr     g+ ++e+e+++nq+lte+dg+
  EEA20643.1 455 ILSGPPGTGKTLLAKATAGESGVPFFSVSGSEFVEMFVGVGPSRVRDLFANARKNT-PCIIFIDEIDAIGKSRskqnFGGGNDERESTLNQILTEMDGF 552
                 79****************************************************98.****************98877789****************** PP

                 TTSSSTEEEEEEESSGGGSTHHHHS.TTSSEEEETT CS
         AAA  97 kkkeskvivigatnrpdkldpallr.gRfdrkieie 131
                 +++e+ v+v++ tnrpd ld+al+r gRfdr+i i+
  EEA20643.1 553 NTSEQ-VVVLAGTNRPDVLDKALMRpGRFDRHITID 587
                 **866.***************************987 PP

>> AAA_lid_3  AAA+ lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.4   0.2   1.9e-15   2.5e-12       6      44 ..     617     655 ..     612     656 .. 0.96
   2 ?   -3.4   0.0       6.9   8.8e+03      19      30 ..     809     820 ..     808     829 .. 0.60

  Alignments for each domain:
  == domain 1  score: 46.4 bits;  conditional E-value: 1.9e-15
   AAA_lid_3   6 eLAerTeGySGADlaalcreAallAlrrgikeitmedfe 44 
                 +LA++T+G+ GAD+a+ ++eAal+A r+  ++++m++fe
  EEA20643.1 617 RLAALTPGFAGADIANCVNEAALVAAREQADSVKMKHFE 655
                 69************************************8 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 6.9
   AAA_lid_3  19 laalcreAallA 30 
                 +  +++eA  ++
  EEA20643.1 809 IRRIVDEAYKRC 820
                 556666665554 PP

>> FtsH_ext  FtsH Extracellular
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.8   0.1   5.4e-11   6.9e-08       9     108 ..     252     352 ..     248     353 .. 0.84

  Alignments for each domain:
  == domain 1  score: 32.8 bits;  conditional E-value: 5.4e-11
    FtsH_ext   9 llllllllslfggsgtgstkeisyseFl.edleqgnvekvvvqestis.alirrptgdgvsttkkgnstttystptlgsvesleekLeealkskgvdve 105
                 +++l + l+   ++ ++++++i+++eF+ +  ++g vek +v + ++  + ++r   +g+  +++  + +  +++++gsv+s+e+kLeea  ++g+  +
  EEA20643.1 252 TSILSYMLYTT-FFPGETSRDITWQEFRsNFFDKGLVEKLTVLNRSRVrVDLNREAVAGEMPDSQAAQRNFHYYFNIGSVDSFERKLEEAHNELGIPTS 349
                 33333333333.88999**********99**************77777799999999999999999999**************************9887 PP

    FtsH_ext 106 ssp 108
                 +++
  EEA20643.1 350 QRV 352
                 765 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0     2e-06    0.0026       3     134 ..     455     574 ..     453     577 .. 0.78

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 2e-06
                 EEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--.........--------..G-SEEEEESGGG--.HHHHHHHHHHHHSSEEE..- CS
       AAA_5   3 lLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreikngttslvdsplvraar..egeilvlDEverae.sevlnsLlslleerrlllee 98 
                 +L GppGtgK+ la+  a   + +++ v ++++ +    +g+ ++           l  +ar  +++i+++DE++ +  s   + +    +er+  l++
  EEA20643.1 455 ILSGPPGTGKTLLAKATAGESGVPFFSVSGSEFVEMFVGVGPSRV---------RDLFANARknTPCIIFIDEIDAIGkSRSKQNFGGGNDERESTLNQ 544
                 89******************************9987777777776.........66666677689**********999555556666677777777777 PP

                 SSSEEE---......-EEEEEESS--.-TT-TTHHH CS
       AAA_5  99 ggelvkaknddllerfrviatanpldrslnelspal 134
                   ++++  n+   e++ v+a +n++d     l++al
  EEA20643.1 545 ILTEMDGFNT--SEQVVVLAGTNRPD----VLDKAL 574
                 7777777664..46688888888888....555555 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   0.1   9.4e-05      0.12      16      45 ..     443     472 ..     439     492 .. 0.83
   2 ?    2.2   0.0      0.16   2.1e+02     123     147 ..     499     522 ..     492     547 .. 0.80
   3 ?   -2.1   0.0       3.4   4.4e+03      72     134 ..     602     668 ..     572     672 .. 0.56

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 9.4e-05
      AAA_16  16 lervrsgrpelvllsGesGvGKsslvrell 45 
                 ++r+ +  p+  +lsG++G+GK+ l+++ +
  EEA20643.1 443 FQRLGAKIPRGAILSGPPGTGKTLLAKATA 472
                 567777778999*************98765 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.16
      AAA_16 123 lkrllallsrderplvlvlDdlqwa 147
                 +++l+a +++   p ++++D+++ +
  EEA20643.1 499 VRDLFANARK-NTPCIIFIDEIDAI 522
                 4566677777.889*******9965 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 3.4
      AAA_16  72 laqalareellrqlldeaesaeleawrekleeala...avpelagaea......srllellkrllallsrde 134
                 l ++l++ e +  l+ ++++  ++ + + +   ++       +a+ e       +++ +++ r +  l++ +
  EEA20643.1 602 LKKILTK-EDMDYLCGRLAALTPGFAGADIANCVNeaaL---VAAREQadsvkmKHFEQAIERVIGGLEK-K 668
                 4444433.6666666666665556566655555553331...2222224446678888888888877776.3 PP

>> TIP49  TIP49 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.0   1.3e-05     0.016      51      89 ..     452     488 ..     400     494 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.3e-05
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49  51 ravLlaGpsgtGktalaiaiskelgedvpfvalsgsevy 89 
                 r+ +l+Gp+gtGkt la a + e g  vpf ++sgse+ 
  EEA20643.1 452 RGAILSGPPGTGKTLLAKATAGESG--VPFFSVSGSEFV 488
                 7889*****************9977..*********975 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0         4   5.2e+03      62      88 ..     110     138 ..      67     156 .. 0.66
   2 !    9.4   0.1   0.00091       1.2       9      24 ..     455     470 ..     451     482 .. 0.88
   3 ?    2.7   0.0      0.11   1.4e+02      83     130 ..     500     564 ..     494     568 .. 0.62

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 4
      AAA_22  62 ralglelka..erlsseellealeqalra 88 
                 ++++   ++   +++++ell++++  l +
  EEA20643.1 110 QFINKLISEsgLPQRESELLRLVQTLLTE 138
                 33332222244456677777777766654 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.00091
      AAA_22   9 vvtGesGtGKTtllrr 24 
                 ++ G++GtGKT+l++ 
  EEA20643.1 455 ILSGPPGTGKTLLAKA 470
                 799**********997 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.11
      AAA_22  83 eqalrarav..ielliiDEaqhlr...s...........eealeeLrsllnl.srkgvqliLvGt 130
                 ++ + ++++  + ++ iDE++ +    s           e  l+++ + ++  +++   ++L+Gt
  EEA20643.1 500 RDLFANARKntPCIIFIDEIDAIGksrSkqnfgggnderESTLNQILTEMDGfNTSEQVVVLAGT 564
                 5555555555678999******9775515566667755555555553333324477777777776 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   2.3e-05     0.029      36      96 ..     454     522 ..     419     530 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 2.3e-05
      RuvB_N  36 vllyGpPGlGkttlakiiakelgvklkitsgPvl.ek.....agdlaalltnleekd..vlfideihrl 96 
                  +l+GpPG Gkt lak  a e gv + + sg    e      ++ +  l++n +++   ++fidei  +
  EEA20643.1 454 AILSGPPGTGKTLLAKATAGESGVPFFSVSGSEFvEMfvgvgPSRVRDLFANARKNTpcIIFIDEIDAI 522
                 589**********************99999875413211111333444444444443338888888765 PP

>> YqzH  YqzH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.0     0.028        36      22      43 ..     185     206 ..     173     208 .. 0.89
   2 ?    7.6   0.0    0.0032       4.1       7      55 ..     765     814 ..     762     818 .. 0.87

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.028
        YqzH  22 elmplseeeqkeLveriqekkk 43 
                 +  +ls++e k L ++i e+k 
  EEA20643.1 185 QFAKLSPDEVKALFKKISEEKP 206
                 7789***************986 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0032
        YqzH   7 eKmirkclrqYgrdtelmpls.eeeqkeLveriqekkkeqedeDlyeive 55 
                  +m+     ++g ++++ pl+ ee+q++L +   e+  ++ d  +  iv+
  EEA20643.1 765 TRMASAMVTKFGMSKAIGPLHfEEDQQQLHKPFSEETARNIDLEIRRIVD 814
                 578888899***********967889***********9999999988886 PP

>> AAA_2  AAA domain (Cdc48 subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   0.00014      0.18       7      84 ..     455     527 ..     452     551 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00014
                 EEE--TTSSHHHHHHHHHHHTT-....-EEEEEGGG-------THHHHHHHHHTTT-HHHHTTS.EEEEETGGG----.- CS
       AAA_2   7 lllgptgvGktelakalaellfvkkekkliradaselleeeevehlvsrligappgyvgaeegG.ivllDEidKihpk.e 84 
                 +l gp g+Gkt+laka+a    v    ++  +  se+ e   +   v    +   + +++++   i+++DEid i ++ +
  EEA20643.1 455 ILSGPPGTGKTLLAKATAGESGV----PFFSVSGSEFVE---MFVGVGPSRVRDLFANARKNTPcIIFIDEIDAIGKSrS 527
                 5789****************998....***********9...44555555555554444444336********9999531 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0         5   6.4e+03     133     160 ..     239     266 ..     238     269 .. 0.83
   2 ?   11.1   0.1   0.00019      0.24      22      69 ..     415     473 ..     401     510 .. 0.71

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 5
   IstB_IS21 133 viekryerrsiiitsnlpfaewdevlgd 160
                 v+e +++ +s i+ts l+   +  +++ 
  EEA20643.1 239 VLEFKFDPSSFIVTSILSYMLYTTFFPG 266
                 78889999*******9999888888775 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00019
   IstB_IS21  22 idfraarsldkrkvkeLatlsfiekkeni...........vllGpsGvGKshlaialgv 69 
                 i+f+   ++d++k++ +   sf++++e +           +l Gp+G+GK+ la a + 
  EEA20643.1 415 IKFADVAGMDEAKMEIMEFVSFLKEAEKFqrlgakiprgaILSGPPGTGKTLLAKATAG 473
                 5566666666666666666666665554322222222332899***********99765 PP

>> AAA_17  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0    0.0002      0.25       2      73 ..     458     530 ..     457     572 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.0002
                 E-TTSSHHHHHHHHHHHHTEEEEEH.HHHHHHHHHTTTSHSSHHHHCTSHHHHHHHHHHHHHHHHHHHHHSSE CS
      AAA_17   2 GgPGsGKgtqceklvekygfthlsa.Gdllreeakrgglakardemrklpleekkelqkeaaekiaeeakkkg 73 
                 G+PG GK+ +++  + + g++++s  G+ + e+    g ++ rd ++++ ++  + +    +++i + ++k++
  EEA20643.1 458 GPPGTGKTLLAKATAGESGVPFFSVsGSEFVEMFVGVGPSRVRDLFANARKNTPCIIFIDEIDAIGKSRSKQN 530
                 9**********************9879******9999999999999999888888877777777777766665 PP

>> DUF2508  Protein of unknown function (DUF2508)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   1.9   0.00031       0.4       5      47 ..      64     106 ..      62     116 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00031
     DUF2508   5 kkkgklkkeedeeLleeIektkeelesakslfensvDlsdeli 47 
                 +k++k++k++deeL e  +++k++  +ak+ f+ ++D  + l+
  EEA20643.1  64 NKNKKVQKSKDEELAEFFASLKKNGPEAKKSFNSAADEKEFLE 106
                 4556********************************9555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (898 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       791  (0.0441185); expected 358.6 (0.02)
Passed bias filter:                      608  (0.0339115); expected 358.6 (0.02)
Passed Vit filter:                        77  (0.00429472); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.79u 0.28s 00:00:01.07 Elapsed: 00:00:00.44
# Mc/sec: 6177.51
//
Query:       EEA20644.1  [L=367]
Description: KH domain RNA-binding protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.7e-41  138.2  10.1    2.9e-17   62.2   0.1    3.2  3  KH_1      KH domain
    1.1e-09   37.9  10.1     0.0073   16.1   1.2    3.5  3  KH_2      KH domain
    3.8e-08   33.1   5.6      0.024   14.5   0.4    3.3  3  KH_4      KH domain
    0.00016   21.7   6.8        0.1   12.7   0.1    3.4  3  KH_5      NusA-like KH domain


Domain annotation for each model (and alignments):
>> KH_1  KH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.5   0.2   5.1e-11   2.3e-07       3      61 ..      51     108 ..      49     113 .. 0.86
   2 !   50.7   1.1   2.6e-17   1.2e-13       2      64 ..     136     198 ..     135     200 .. 0.94
   3 !   62.2   0.1   6.5e-21   2.9e-17       1      65 [.     287     351 ..     287     352 .. 0.91

  Alignments for each domain:
  == domain 1  score: 30.5 bits;  conditional E-value: 5.1e-11
                 EEEEGGGHHHHHHTGGGHHHHHHHHHHT-EEEEES.STT...T.-EEEEEESHHHHHHHH CS
        KH_1   3 rilvPsslvgriIGkgGsnIkeIreetgakIkvpk.sedegsderevtisGspeavekAk 61 
                 r +v s+ +g iIGk G+n+ ++r+etg+k  v k  +    ++r++t++G  +++++A 
  EEA20644.1  51 RAIVSSKEAGVIIGKAGKNVADLRDETGVKAGVSKvVQGV--HDRVLTVTGGLQGCARAY 108
                 55799999************************99888886..*********666688876 PP

  == domain 2  score: 50.7 bits;  conditional E-value: 2.6e-17
                 EEEEEGGGHHHHHHTGGGHHHHHHHHHHT-EEEEESSTT....T.-EEEEEESHHHHHHHHHHH CS
        KH_1   2 lrilvPsslvgriIGkgGsnIkeIreetgakIkvpksedeg.sderevtisGspeavekAkeli 64 
                 +r+l+ ++++g iIG++G +Ik+I++ +g++++    e+ + s+er+v+++G+pe++ekA+ +i
  EEA20644.1 136 IRLLISHNQMGTIIGRQGLKIKHIQDASGVRMVAQ-KEMLPqSTERIVEVQGTPEGIEKAVWEI 198
                 5899**********************99****977.888889******************9988 PP

  == domain 3  score: 62.2 bits;  conditional E-value: 6.5e-21
                 EEEEEEGGGHHHHHHTGGGHHHHHHHHHHT-EEEEESSTT....T.-EEEEEESHHHHHHHHHHHH CS
        KH_1   1 tlrilvPsslvgriIGkgGsnIkeIreetgakIkvpksedeg.sderevtisGspeavekAkelie 65 
                 t+ i++P+++vg+iIG+gGs+I eIr+ +ga+I +    +++ ++er++ti Gs++a ekA++l++
  EEA20644.1 287 TQNISIPADMVGCIIGRGGSKISEIRRSSGARISIA-KAPHDeTGERMFTIMGSAQANEKALYLLY 351
                 5779***********************88*****98.566667*******************9987 PP

>> KH_2  KH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.1   0.2   2.8e-05      0.13      28      55 ..      51      78 ..      34      87 .. 0.85
   2 !   16.1   1.2   1.6e-06    0.0073      25      65 ..     134     172 ..     110     201 .. 0.76
   3 !   14.1   0.2   6.9e-06     0.031      27      59 ..     288     320 ..     273     325 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 2.8e-05
                EEEEEESCHHHHHTGGGHHHHHHHHHHH CS
        KH_2 28 iiviresqpgivIGkgGsnikkigkelr 55
                + ++ + + g++IGk G+n+  ++ e +
  EEA20644.1 51 RAIVSSKEAGVIIGKAGKNVADLRDETG 78
                567889999*************998876 PP

  == domain 2  score: 16.1 bits;  conditional E-value: 1.6e-06
                 CEEEEEEEESCHHHHHTGGGHHHHHHHHHHHHHHHHHHTTC CS
        KH_2  25 nrviiviresqpgivIGkgGsnikkigkelrkdieklegkk 65 
                 + +++ i  +q+g +IG++G +ik i+ + + ++  + +k+
  EEA20644.1 134 HPIRLLISHNQMGTIIGRQGLKIKHIQDASGVRM--VAQKE 172
                 56889999********************999998..55555 PP

  == domain 3  score: 14.1 bits;  conditional E-value: 6.9e-06
                 EEEEEEESCHHHHHTGGGHHHHHHHHHHHHHHH CS
        KH_2  27 viiviresqpgivIGkgGsnikkigkelrkdie 59 
                  +i i +   g +IG+gGs+i +i+   + +i 
  EEA20644.1 288 QNISIPADMVGCIIGRGGSKISEIRRSSGARIS 320
                 56666677789***************9999985 PP

>> KH_4  KH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   0.1   3.6e-05      0.16      20      52 ..      39      71 ..      31      75 .. 0.80
   2 !   14.5   0.4   5.3e-06     0.024      24      55 ..     129     160 ..     110     164 .. 0.81
   3 !    7.8   0.1   0.00065       2.9      24      52 ..     281     309 ..     271     313 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3.6e-05
        KH_4 20 vteeeeeeeveielnvegedlGrvIGkrGrtld 52
                 +ee+ +   +++  v++++ G++IGk G+++ 
  EEA20644.1 39 TEEEYAQAVLTLRAIVSSKEAGVIIGKAGKNVA 71
                5666777778889999**************976 PP

  == domain 2  score: 14.5 bits;  conditional E-value: 5.3e-06
        KH_4  24 eeeeeveielnvegedlGrvIGkrGrtldAlq 55 
                 +++ ++ i+l ++ +++G +IG++G  ++ +q
  EEA20644.1 129 QNNGTHPIRLLISHNQMGTIIGRQGLKIKHIQ 160
                 5678999******************8887666 PP

  == domain 3  score: 7.8 bits;  conditional E-value: 0.00065
        KH_4  24 eeeeeveielnvegedlGrvIGkrGrtld 52 
                 ++ee ++ ++++  + +G +IG+ G  ++
  EEA20644.1 281 DGEEVQTQNISIPADMVGCIIGRGGSKIS 309
                 4667778899999************9876 PP

>> KH_5  NusA-like KH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.4     0.011        47       8      36 ..      53      76 ..      49      89 .. 0.85
   2 !    6.8   0.1    0.0016       7.3      13      35 ..     143     161 ..     137     166 .. 0.87
   3 !   12.7   0.1   2.3e-05       0.1      17      46 ..     295     323 ..     285     331 .. 0.85

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.011
        KH_5  8 aVkshnpnvdpvGaivgkkGsrikavsse 36
                +V s++     +G i+gk G+++  + +e
  EEA20644.1 53 IVSSKE-----AGVIIGKAGKNVADLRDE 76
                566666.....9***********999887 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.0016
        KH_5  13 npnvdpvGaivgkkGsrikavss 35 
                 n    ++G+i+g++G +ik + +
  EEA20644.1 143 N----QMGTIIGRQGLKIKHIQD 161
                 3....79************9976 PP

  == domain 3  score: 12.7 bits;  conditional E-value: 2.3e-05
        KH_5  17 dpvGaivgkkGsrikavsseLkgekidvve 46 
                 d vG i+g++Gs+i+++ +   g +i + +
  EEA20644.1 295 DMVGCIIGRGGSKISEIRRSS-GARISIAK 323
                 89****************997.98888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (367 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       325  (0.0181271); expected 358.6 (0.02)
Passed bias filter:                      256  (0.0142785); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.47
# Mc/sec: 2336.19
//
Query:       EEA20645.1  [L=354]
Description: alcohol dehydrogenase, zinc-containing, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      7e-29   99.9   1.6    1.1e-28   99.2   1.6    1.4  1  ADH_N         Alcohol dehydrogenase GroES-like domain
    1.7e-16   60.4   0.0    3.2e-16   59.5   0.0    1.5  1  ADH_zinc_N    Zinc-binding dehydrogenase
    3.4e-06   26.7   0.0    4.8e-06   26.2   0.0    1.3  1  Glu_dehyd_C   Glucose dehydrogenase C-terminus
    4.2e-05   23.4   0.4    9.4e-05   22.2   0.4    1.6  1  ADH_N_assoc   Alcohol dehydrogenase GroES-associated
     0.0026   18.8   0.0     0.0057   17.7   0.0    1.6  1  ADH_zinc_N_2  Zinc-binding dehydrogenase
  ------ inclusion threshold ------
        0.1   11.9   0.0        0.3   10.3   0.0    1.7  2  AlaDh_PNT_C   Alanine dehydrogenase/PNT, C-terminal domain


Domain annotation for each model (and alignments):
>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.2   1.6   3.8e-32   1.1e-28       2     103 ..      32     134 ..      31     140 .. 0.94

  Alignments for each domain:
  == domain 1  score: 99.2 bits;  conditional E-value: 3.8e-32
                 TEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS--TT-EEEE-SEEE-SSSHHHHTT-GGG-TTBEETTTS.S-SSSBSEE CS
       ADH_N   2 gevlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkklkvGdrVvvepliscgeCaaCkegeenlCeeakllgvs.ldGgfaeyv 99 
                 ++v++kvk++++Cgs+lh+++g  + + k+++i+GHE++G+v+e g++vk+l+vGd +v ++++scg+C +Ck+g ++ C++  l+g   ldGg+aey 
  EEA20645.1  32 TDVIVKVKYTALCGSELHVFRG--HQPSKTGFIMGHEFTGTVVEKGDDVKTLAVGDVIVSPFTTSCGTCFYCKQGFSSRCANSLLFGCPvLDGGQAEYA 128
                 68*******************9..799**************************************************************9********* PP

                 EEC..G CS
       ADH_N 100 vvp..e 103
                  vp  +
  EEA20645.1 129 RVPyaD 134
                 **9533 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.5   0.0   1.1e-19   3.2e-16       1     109 [.     187     297 ..     187     321 .. 0.83

  Alignments for each domain:
  == domain 1  score: 59.5 bits;  conditional E-value: 1.1e-19
                 HHHHHHHHHHHHTT-.EEEEEESSHHHHHHHHHTTESEEEETTTC.HHHHHHHHHTTTSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSCTSSEEEE CS
  ADH_zinc_N   1 gvGlaavqlAkalGa.eviavdsseeklelakklGadevinykea.dlverikeltggegvdvvfecvGsgatleaalkllkpgGrlvvvGggkgeeef 97 
                 +vGl+a+  A  ++  +  avds e +lelakklGa+     k+   l++r+kelt+g+g+dvv+e+vG   +l++a++ll+p G++  vG+   e + 
  EEA20645.1 187 PVGLLAIINALEYKPkHLLAVDSVEPRLELAKKLGAEPWNFLKDReGLDKRVKELTDGRGADVVIEVVGLSPALRMAFDLLRPWGTISSVGVHNAEIPW 285
                 7999**999999999999******************98766666669********************************************85554445 PP

                 EHHHHHHTT-EE CS
  ADH_zinc_N  98 dlrnlllkeksi 109
                 + +    k++++
  EEA20645.1 286 TGSEAYGKNLKL 297
                 555555555555 PP

>> Glu_dehyd_C  Glucose dehydrogenase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.2   0.0   1.6e-09   4.8e-06      33     135 ..     179     281 ..     164     350 .. 0.83

  Alignments for each domain:
  == domain 1  score: 26.2 bits;  conditional E-value: 1.6e-09
  Glu_dehyd_C  33 salvlGaGslGLLalalleaeerglervyvlgrrdrpdptidlveelGat...Yvdsre...tpvdeipeaseemdlvvEaTGsakhafeaiealapn 124
                  +++v+G G++GLLa  +++a   +++  + l+  d  +p+++l ++lGa    + + re   + v+e+    +  d+v+E  G ++++  a + l+p 
   EEA20645.1 179 TVVVIGCGPVGLLA--IINA--LEYKPKHLLAV-DSVEPRLELAKKLGAEpwnFLKDREgldKRVKEL-TDGRGADVVIEVVGLSPALRMAFDLLRPW 270
                  789***********..5554..68998999985.889************6433666776222466666.456789*********************** PP

  Glu_dehyd_C 125 GvaaLlGvped 135
                  G +  +Gv + 
   EEA20645.1 271 GTISSVGVHNA 281
                  *******9875 PP

>> ADH_N_assoc  Alcohol dehydrogenase GroES-associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.2   0.4   3.2e-08   9.4e-05       1      23 []       7      29 ..       7      29 .. 0.96

  Alignments for each domain:
  == domain 1  score: 22.2 bits;  conditional E-value: 3.2e-08
  ADH_N_assoc  1 MKAVTyqGpkdVrVeeVPDPkIe 23
                 MKAV+++Gp +V+ e+ P P+I+
   EEA20645.1  7 MKAVVFHGPYQVAIEDWPVPRIQ 29
                 ****************9999998 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0   1.9e-06    0.0057      13     115 ..     237     335 ..     220     347 .. 0.66

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 1.9e-06
                   THHHHH-TT-EEEEEES-HHHHH.HHHHHHEEEEEEEEE--.--.S-EEE-CHHHCTTT-EEEE--GGG....-.-HHHHHHHHHHHHHHH----EE CS
  ADH_zinc_N_2  13 dfeaatggegvDvvldtvggealleaslkvlpggGrlvsig.gpplsaallkpakkrkgrsvkyeflfs.mkasaqadileelaalieeGklrpvvd 107
                   ++++ t+g+g Dvv++ vg   +l+ ++++l++ G++ s+g      a++++  +++ g+++k+++  + +++    ++le l +   ++ l    d
    EEA20645.1 237 RVKELTDGRGADVVIEVVGLSPALRMAFDLLRPWGTISSVGvH---NAEIPWTGSEAYGKNLKLQMGRCpVRSV-FPQALESLKR--NQHLLGFMAD 327
                   4447799************55555*******888***999954...5666777676777777777666522222.3332333322..2223555555 PP

                   EEEEGGGH CS
  ADH_zinc_N_2 108 rvfpleea 115
                   +v+pl+ea
    EEA20645.1 328 KVMPLSEA 335
                   55555555 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0    0.0001       0.3      30      90 ..     179     239 ..     165     257 .. 0.76
   2 ?   -2.2   0.0      0.69   2.1e+03     157     177 ..     277     295 ..     272     299 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.0001
                  EEEEESTSHHHHHHHHHHHHTT.-EEEEEESSHHHHHHHHHTTTCECEEHCHHHHHHHHHHH CS
  AlaDh_PNT_C  30 kvlviGgGvaGlqAiatakglg.akVtvlDvrparleqleslgakfvevlksqeellaeavk 90 
                  +v+viG G +Gl Ai +a + +  +  ++D  + rle  ++lga+  + lk ++e l+++vk
   EEA20645.1 179 TVVVIGCGPVGLLAIINALEYKpKHLLAVDSVEPRLELAKKLGAEPWNFLK-DREGLDKRVK 239
                  79****************998735678999999999999999998666644.3444455544 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.69
                  EBSTGGGGSHHHHHHHHHHHH CS
  AlaDh_PNT_C 157 gvanlpgavprtasalltnnt 177
                  gv+n  +++p+t s+++ +n+
   EEA20645.1 277 GVHN--AEIPWTGSEAYGKNL 295
                  5554..679********9996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (354 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       391  (0.0218082); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.54u 0.24s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 2411.95
//
Query:       EEA20646.1  [L=450]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (450 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       417  (0.0232584); expected 358.6 (0.02)
Passed bias filter:                      282  (0.0157287); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.52u 0.24s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 3139.40
//
Query:       EEA20647.1  [L=712]
Description: TBC domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.2e-31  109.2   1.3    4.7e-31  108.1   1.3    1.6  1  RabGAP-TBC  Rab-GTPase-TBC domain
  ------ inclusion threshold ------
        2.2    8.2   5.0         34    4.3   5.0    2.2  1  POP1        Ribonucleases P/MRP protein subunit POP1


Domain annotation for each model (and alignments):
>> RabGAP-TBC  Rab-GTPase-TBC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  108.1   1.3   5.2e-35   4.7e-31       3     215 .]      41     322 ..      39     322 .. 0.78

  Alignments for each domain:
  == domain 1  score: 108.1 bits;  conditional E-value: 5.2e-35
  RabGAP-TBC   3 lRgevWklllgyep...........................evkrlkksekkqeksekeksklekseeske.lsqIkkDvprtfpesesfknkqgqnqL 73 
                 lR+ +Wk++l   +                           +++ ++ ++  +   e+e+s ++  ++++     I +Dv+r ++++ +f+++++++++
  EEA20647.1  41 LRSVCWKIFLLCDDldrskwidrltdtrsaydslkdhflkyIKHPNDLQSTVDPLAEDEESPWQALRHDEAtRAEIFQDVERCLQDNCFFREPSTKSMM 139
                 56666666665555666666666666666666666666665445555555556666667777777777766699***********889*********** PP

  RabGAP-TBC  74 eriLkaysiynpevgYcqGmndivapll.......................lvsldeee.............aFwcfvsLlekyklrdlytsslpg... 133
                   iL++ys+ np++gY qGm+ ++ap+l                                            +F++f+s +  +  r++y+++ ++   
  EEA20647.1 140 LDILFVYSKLNPDLGYRQGMHELLAPILwvverdavtqsskhipvdttddeS------VmlqlldanyiesdSFNLFCSVM--QVARSFYEHTDNRpvn 230
                 ****************************877777777777766655555550......05555555566677*********..9999999999944422 PP

  RabGAP-TBC 134 ........lkrklkvleellkkkdpklykhlkeegldlelfaikwfltlflrefpletvlrlwD.lllegekfvllr.valailklleeell 215
                         + r   + +ell   d +l+ hl+++++ +++f+++w+  lf ref+++ +l +wD l+++g + +l+  +++a+l + +++ll
  EEA20647.1 231 geaemapiVARSEFIHNELLMVADHELAIHLNTIEILPQIFLTRWIRLLFGREFSFDDTLLIWDlLFANGLRATLIDhICVAMLLRIRWQLL 322
                 23333444666666**************************************************88889999999999******99999986 PP

>> POP1  Ribonucleases P/MRP protein subunit POP1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   5.0    0.0038        34      21      69 ..     418     466 ..     408     629 .. 0.62

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.0038
        POP1  21 kasstraFQslPrklRRRtaSHnvkRvPkrlrarakremakdntptvea 69 
                 + + +  FQ++   l RRt  + v +  +   + akr+ma+ +    + 
  EEA20647.1 418 QRTLESLFQDVSEGLQRRTEGWGVAKAVRGAVSEAKRNMANAEVGGISP 466
                 4455678*******************************98877332222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (712 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       988  (0.0551063); expected 358.6 (0.02)
Passed bias filter:                      537  (0.0299515); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.30s 00:00:00.97 Elapsed: 00:00:00.44
# Mc/sec: 4808.59
//
Query:       EEA20648.1  [L=1138]
Description: serine/threonine protein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.3e-56  191.1   0.0    3.4e-56  190.5   0.0    1.3  1  Pkinase         Protein kinase domain
    3.3e-20   72.4   0.0    4.9e-20   71.9   0.0    1.2  1  Pkinase_Tyr     Protein tyrosine kinase
      1e-05   25.0   0.0    2.7e-05   23.6   0.0    1.7  2  Kinase-like     Kinase-like
     0.0011   19.0   0.1      0.015   15.3   0.1    2.1  2  APH             Phosphotransferase enzyme family
     0.0013   17.7   0.0     0.0022   17.0   0.0    1.2  1  Haspin_kinase   Haspin like kinase domain
     0.0049   16.5   0.0      0.013   15.1   0.0    1.6  1  RIO1            RIO1 family
     0.0049   15.7   0.0     0.0085   14.9   0.0    1.3  1  Pkinase_fungal  Fungal protein kinase


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  190.5   0.0   1.3e-59   3.4e-56       1     264 []     875    1135 ..     875    1135 .. 0.89

  Alignments for each domain:
  == domain 1  score: 190.5 bits;  conditional E-value: 1.3e-59
                  EEEEEEEEEESSEEEEEEEET.TTTEEEEEEEEECHCHCHHHH......HHHHHHHHHHHHHS.....CTTB--EEEEEEESSEEE..EEEE--TTE CS
     Pkinase    1 yekleklGeGsfGkVykavek.etgkivAvKkikkekakkkke......kkvlrEikilkklk.....hpnivrlyevfeekdely..lvleyvegg 83  
                  y+ +e++G+G++G+V  a+ k +  k++++K + k+++  ++        +v  Ei++l  l+     hpniv++ ++fe++ ++y  +v   ++g 
  EEA20648.1  875 YVIIEEMGQGAYGQVKLARLKkNPAKKMVLKYVTKKRILVDTWtrdrrlGTVPLEIHVLDYLRrdglrHPNIVEMEGFFEDEINYYieMVPHGLPGM 971 
                  67899**********999855056899*********9987777777888999*******988777888*************8888855777888889 PP

                  BHHHHHHHHSS--HHHHHHHHHHHHHHHHHHHHTT.EE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCSBCTTTSCGGGS-HHHHTTSCB.SHHH CS
     Pkinase   84 eladllerkgslseeeakkiakqilegleylHskg.iiHrDlKpeNiLidekgelKitDFGlakelessskltsfvgtseYlAPEvlkeney.skkv 178 
                  +l+d++e k++++e e+++i+kq++ ++++lH k  ++HrD+K+eN+ +d +g +K++DFG a+ ++++  ++ fvgt +Y APEvl++++y +k+ 
  EEA20648.1  972 DLFDYIELKSNMDEGECRNIFKQVVDAIHHLHTKAlVVHRDIKDENVVLDGEGRIKLIDFGSAAYIKNGP-FDVFVGTIDYAAPEVLQGKSYrGKEQ 1067
                  9*******************************6665********************************99.************************** PP

                  HHHHHHHHHHHHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCTSHH...HHHTTS-HHHHHHHHHHT-SSGCCSTTHHHHHTSGGG CS
     Pkinase  179 DvWslGvilyelltgkppfsgekgkekvekeldqlekilkilgetkeklpeaseiseeakdllkkllkkdpkkRltaeellqhpyl 264 
                  DvW+lG++ly+++++++pf+          ++d+      il++          +se+++dl++++l++d  +R+t++e+++hp++
  EEA20648.1 1068 DVWALGILLYTIVYKENPFY----------NVDE------ILDH--PLRVPFLPFSEDCIDLIRRMLDRDVDNRITISEVVDHPWM 1135
                  ********************..........4444......2211..222234568******************************7 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.9   0.0   1.9e-23   4.9e-20       3     210 ..     877    1090 ..     875    1132 .. 0.71

  Alignments for each domain:
  == domain 1  score: 71.9 bits;  conditional E-value: 1.9e-23
                   EEEEEEEESSEEEEEEEEET..TTTSSEEEEEEEEEST.......TSSHHHHHHHHHHHHHHHT.....S-BTTB--EEEEEESSSSEEEEEE--T CS
  Pkinase_Tyr    3 lgkklGeGafGkVvegtlkg..ekekkevkVavKtlke.......eateeekeelleeakimkk.....lkhpnivkllgvctkeepllivteyvk 84  
                   + +++G+Ga+G+V  ++lk+         k ++K +++        +++++   +  e++++       l+hpniv++ g+  +e +++i  e+v+
   EEA20648.1  877 IIEEMGQGAYGQVKLARLKKnpA-----KKMVLKYVTKkrilvdtWTRDRRLGTVPLEIHVLDYlrrdgLRHPNIVEMEGFFEDEINYYI--EMVP 965 
                   5789***************6431.....3333333322111111133344455566688888641112258************7766554..5555 PP

                   TE....BHHHHHHHTCTTTSBHHHHHHHHHHHHHHHHHHHHTT.EEEST-SGGGEEEEETTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HH CS
  Pkinase_Tyr   85 gG....dLlkfLrkkekekltlkdllsfalqvAkGmeyLeskk.lvHrdlaarNvLlsenkvvkisDfGLardiekddeyvkkeeaklpvkWmapE 175 
                   +G    dL ++++ k  ++++  +  ++  qv +++++L++k  +vHrd+   Nv+l+ +  +k+ DfG a  i++       +     + + apE
   EEA20648.1  966 HGlpgmDLFDYIELK--SNMDEGECRNIFKQVVDAIHHLHTKAlVVHRDIKDENVVLDGEGRIKLIDFGSAAYIKNG----PFDVFVGTIDYAAPE 1055
                   555555******998..99*********************999679****************************333....344566789****** PP

                   HHHHSEEE.HHHHHHHHHHHHHHHHTTSSGTTTTSH CS
  Pkinase_Tyr  176 slkekkft.sksDvWsfGvllwEiftlgespypglk 210 
                   +l+ k++  ++ DvW+ G+ll+ i+   e+p+ +++
   EEA20648.1 1056 VLQGKSYRgKEQDVWALGILLYTIVY-KENPFYNVD 1090
                   ******983568************98.677776654 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0       2.7   6.9e+03      75      95 ..     474     494 ..     469     495 .. 0.84
   2 !   23.6   0.0   1.1e-08   2.7e-05     144     288 .]     987    1123 ..     973    1123 .. 0.80

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 2.7
  Kinase-like  75 eqAkdhlrlllpfdlvkiqkk 95 
                  + A++ + +ll+ d+v iqk+
   EEA20648.1 474 HPANKSRGVLLCGDVVPIQKR 494
                  568899999*********997 PP

  == domain 2  score: 23.6 bits;  conditional E-value: 1.1e-08
  Kinase-like  144 iarlllTlqlirlaanLqakgl.vhgkftvdnllldekgglmlggftaLvragtkvvl.seve.kgfaPpEllgsrggytrknktkmthkldaWql 236 
                    +r +   q++  + +L+ k l vh +++ +n++ld +g+++l +f++    + +++    v    +a pE+l  +  y+         + d+W+l
   EEA20648.1  987 ECRNIF-KQVVDAIHHLHTKALvVHRDIKDENVVLDGEGRIKLIDFGSAAYIK-NGPFdVFVGtIDYAAPEVLQGK-SYRG-------KEQDVWAL 1072
                   577777.799999*****998637**********************9865443.3443122323679999*99884.3555.......467***** PP

  Kinase-like  237 GlviyriwclklPltlateeakeewkfklckkipekvkaLlkkfLqlsqedR 288 
                   G+  y i   + P+ ++ e         +  + +e    L++++L +++++R
   EEA20648.1 1073 GILLYTIVYKENPFYNVDEILDHP-LRVPFLPFSEDCIDLIRRMLDRDVDNR 1123
                   ***************999988887.444555999*999*******9999888 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0     0.044   1.1e+02      35     106 ..     924    1003 ..     907    1005 .. 0.77
   2 !   15.3   0.1   5.8e-06     0.015     160     198 ..    1002    1036 ..     993    1038 .. 0.86

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.044
                  HHHHHHHHHHHHHHHTT-B--B-CTTB..S-EEETTEEEEEEE----EE-SS......HHHHHHHHHHHHHHHHHHCCHH CS
         APH   35 eeirrevallrlLakagvpvPevlagd..tddeeigllfalieyvpgrsllr......klsaaqlpellealgeflaalh 106 
                   +++ e ++l++L++ g++ P ++ ++    de +++   +  ++pg +l +      ++++ + ++++ ++++++ +lh
  EEA20648.1  924 GTVPLEIHVLDYLRRDGLRHPNIVEMEgfFEDEINYYIEMVPHGLPGMDLFDyielksNMDEGECRNIFKQVVDAIHHLH 1003
                  5778899***********7777775333257777777666667777777777777777777***************9999 PP

  == domain 2  score: 15.3 bits;  conditional E-value: 5.8e-06
                  --SSS-EEEE-SS-SGGGEEEC..TTEEEEE---TT-EE CS
         APH  160 lpgelptvllHgDlhpgNllvdpddgrvtGviDfedagl 198 
                  l+   ++ ++H+D++  N+++d ++gr+  +iDf+ a +
  EEA20648.1 1002 LH--TKALVVHRDIKDENVVLD-GEGRI-KLIDFGSAAY 1036
                  44..68999*************.99999.9*****9876 PP

>> Haspin_kinase  Haspin like kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0   8.6e-07    0.0022     203     254 ..     983    1034 ..     934    1059 .. 0.83

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 8.6e-07
  Haspin_kinase  203 kswkqalsifwqivkiLyvaEtkfeFEHRdLhldniLvdknlnvtlidlkls 254 
                      +  ++ +if q+v  ++   tk    HRd++ +n+ +d ++ + lid+  +
     EEA20648.1  983 MDEGECRNIFKQVVDAIHHLHTKALVVHRDIKDENVVLDGEGRIKLIDFGSA 1034
                     344589******************************************9765 PP

>> RIO1  RIO1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0     5e-06     0.013      97     153 ..     978    1035 ..     967    1041 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 5e-06
                  BHHHCG-HHHHHHHHHHHHHHHHHHHHTSTEEESS-STTSEEEETT.EEEE--GTTEE CS
        RIO1   97 klkdveeeeeaeelyeevleemrklykeaglvHaDLSeyNvlvded.kvviIDvsQav 153 
                  +lk   +e e ++++++v+++++ l ++a +vH D+ + Nv++d + ++ +ID++ a 
  EEA20648.1  978 ELKSNMDEGECRNIFKQVVDAIHHLHTKALVVHRDIKDENVVLDGEgRIKLIDFGSAA 1035
                  5666666899*********************************9988******98765 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   3.3e-06    0.0085     309     389 ..     989    1060 ..     978    1081 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 3.3e-06
  Pkinase_fungal  309 lealrDaIkghrsLflkagiLHrDiSenNilitdskkegerkglLiDLDlakelsddssesgarertGTleFmaievlkge 389 
                       + +++++ +   L++ka ++HrDi  +N+++      ge +  LiD+  a  +++          +GT+ + a evl+g+
      EEA20648.1  989 RNIFKQVVDAIHHLHTKALVVHRDIKDENVVLD-----GEGRIKLIDFGSAAYIKN--GPF--DVFVGTIDYAAPEVLQGK 1060
                      5567788888899*******************9.....9999*********99995..333..468999999999999975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1138 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       349  (0.0194657); expected 358.6 (0.02)
Passed bias filter:                      306  (0.0170673); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.83u 0.31s 00:00:01.13 Elapsed: 00:00:00.49
# Mc/sec: 6915.64
//
Query:       EEA20649.1  [L=716]
Description: F-box domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.6e-12   47.1   0.0    4.5e-12   45.7   0.0    1.9  1  F-box-like   F-box-like
    3.4e-10   39.1  12.1       0.21   11.7   0.0    6.8  8  LRR_6        Leucine Rich repeat
    1.8e-09   37.3   0.0    7.8e-09   35.2   0.0    2.3  1  F-box        F-box domain
      2e-05   24.8  10.6      0.087   13.3   0.1    5.4  6  LRR_4        Leucine Rich repeats (2 copies)
    0.00022   21.5   0.6     0.0014   18.9   0.0    2.3  2  PRANC        PRANC domain
     0.0063   16.9   6.7         21    6.2   0.1    5.7  5  LRR_1        Leucine Rich Repeat
  ------ inclusion threshold ------
       0.05   12.9   0.0      0.093   12.0   0.0    1.3  1  Phage_TTP_1  Phage tail tube protein


Domain annotation for each model (and alignments):
>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.7   0.0   1.8e-15   4.5e-12       1      47 [.     168     213 ..     168     214 .. 0.95

  Alignments for each domain:
  == domain 1  score: 45.7 bits;  conditional E-value: 1.8e-15
  F-box-like   1 isrLPdEiLlqIFsyLppsdLlrlalVCrrWrrvaldtplLWrrlvl 47 
                 +++ P+Ei  +I+ yL p++++r++lV++ W+++++d  +LW+++ +
  EEA20649.1 168 WNDMPNEIKTKILGYLTPKEIVRCSLVSKAWHDMCFDG-QLWYQIDT 213
                 6789**********************************.****9986 PP

>> LRR_6  Leucine Rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0         2   5.2e+03       5      13 ..     236     244 ..     234     245 .. 0.84
   2 ?    1.8   0.1      0.12   3.1e+02       2      12 ..     287     297 ..     286     307 .. 0.84
   3 !   11.6   0.1   9.2e-05      0.24       2      21 ..     313     333 ..     312     335 .. 0.92
   4 ?    5.2   0.1      0.01        27       3      23 ..     366     386 ..     364     386 .. 0.91
   5 !   10.8   0.0   0.00016      0.42       5      24 .]     408     428 ..     405     428 .. 0.93
   6 ?   -3.9   0.0         7   1.8e+04       8      18 ..     437     448 ..     437     450 .. 0.79
   7 !   11.7   0.0   8.3e-05      0.21       5      21 ..     488     505 ..     487     507 .. 0.92
   8 ?   -2.1   0.1       2.2   5.6e+03       1      15 [.     510     524 ..     510     526 .. 0.75

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 2
       LRR_6   5 LteLdLsgN 13 
                 ++ L+L+g+
  EEA20649.1 236 VRDLNLRGC 244
                 689****99 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.12
       LRR_6   2 nthLteLdLsg 12 
                 nt+L++ ++sg
  EEA20649.1 287 NTSLKYINVSG 297
                 9********98 PP

  == domain 3  score: 11.6 bits;  conditional E-value: 9.2e-05
       LRR_6   2 nthLteLdLsgNd.IgDeGae 21 
                 ++ L++L++s++  I+ +G++
  EEA20649.1 313 CSQLETLNVSWCLnIDTKGLK 333
                 899****************97 PP

  == domain 4  score: 5.2 bits;  conditional E-value: 0.01
       LRR_6   3 thLteLdLsgNdIgDeGaeaL 23 
                 ++L+ L L   dI+De ++ L
  EEA20649.1 366 NTLERLVLHRTDITDESLKML 386
                 89***************9986 PP

  == domain 5  score: 10.8 bits;  conditional E-value: 0.00016
       LRR_6   5 LteLdLsgNd.IgDeGaeaLa 24 
                 L++Ld+  +  I+D+G+++La
  EEA20649.1 408 LRHLDIHQCTnITDAGLSSLA 428
                 9******************98 PP

  == domain 6  score: -3.9 bits;  conditional E-value: 7
       LRR_6   8 LdLsgNd.IgDe 18 
                 L++s +  ++D+
  EEA20649.1 437 LQISQCTeLTDD 448
                 678888889997 PP

  == domain 7  score: 11.7 bits;  conditional E-value: 8.3e-05
       LRR_6   5 LteLdLsgNd.IgDeGae 21 
                 L++L++s++d IgD G+ 
  EEA20649.1 488 LEHLNVSYCDsIGDIGML 505
                 89*************985 PP

  == domain 8  score: -2.1 bits;  conditional E-value: 2.2
       LRR_6   1 snthLteLdLsgNdI 15 
                 +++ L++L++    +
  EEA20649.1 510 NCRQLRSLEMDNTRV 524
                 6899****9876655 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.2   0.0   3.1e-12   7.8e-09       3      46 ..     168     211 ..     166     213 .. 0.92

  Alignments for each domain:
  == domain 1  score: 35.2 bits;  conditional E-value: 3.1e-12
                 HHHS-HHHHHHHHHTS-HHHHHHHCTT-HHHHHHHTTHHHHHHH CS
       F-box   3 lsrLPsevlrhILerLplsdllalrrVSkgwrilidsdrlwcks 46 
                 + ++P+e+  +IL +L +++++++++VSk w++++ +  lw  +
  EEA20649.1 168 WNDMPNEIKTKILGYLTPKEIVRCSLVSKAWHDMCFDGQLWYQI 211
                 99*********************************998888665 PP

>> LRR_4  Leucine Rich repeats (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.1     0.016        41       9      32 ..     269     297 ..     264     306 .. 0.77
   2 ?    2.0   0.2      0.12   3.2e+02       1      31 [.     288     322 ..     288     345 .. 0.74
   3 ?   -1.8   0.0       1.9   4.8e+03       3      16 ..     368     381 ..     367     386 .. 0.81
   4 !    8.7   0.0   0.00091       2.3       3      38 ..     408     447 ..     407     452 .. 0.85
   5 ?    0.8   0.0      0.29   7.4e+02       2      38 ..     433     467 ..     432     479 .. 0.62
   6 !   13.3   0.1   3.4e-05     0.087       3      39 ..     488     527 ..     487     531 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.016
                 -..SS---E-S-....HHH-TT--EEE-.- CS
       LRR_4   9 s..nNqltdipl....leklpnLkeLdLsg 32 
                 s  ++++ +i+l    l+ +++Lk++++sg
  EEA20649.1 269 SveGCRIDKISLngffLR-NTSLKYINVSG 297
                 444799999999998777.9*******987 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.12
                 SS--EEE--SS---E-S-.....HHH.-TT--EEE-. CS
       LRR_4   1 pnLevLdLsnNqltdipl.....lek.lpnLkeLdLs 31 
                 ++L++++ s+  l+++ +     +++ + +L++L++s
  EEA20649.1 288 TSLKYINVSG--LSTVTNsamkiIAQtCSQLETLNVS 322
                 5788888887..7777774444433559999999973 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 1.9
                 --EEE--SS---E- CS
       LRR_4   3 LevLdLsnNqltdi 16 
                 Le L L+ + +td 
  EEA20649.1 368 LERLVLHRTDITDE 381
                 89999999999985 PP

  == domain 4  score: 8.7 bits;  conditional E-value: 0.00091
                 --EEE--SS.---E-S-..HH.H-TT--EEE-.-S----- CS
       LRR_4   3 LevLdLsnN.qltdipl..le.klpnLkeLdLsgNnlitd 38 
                 L++Ld++++ ++td +l  l+ + p L+ L +s+++ +td
  EEA20649.1 408 LRHLDIHQCtNITDAGLssLAyNVPALQGLQISQCTELTD 447
                 9******7669***999775567*********99988876 PP

  == domain 5  score: 0.8 bits;  conditional E-value: 0.29
                 S--EEE--SS.---E-S-...HHH-TT--EEE-.-S----- CS
       LRR_4   2 nLevLdLsnN.qltdipl...leklpnLkeLdLsgNnlitd 38 
                  L+ L +s++  ltd +    ++  p+L ++d+ +     d
  EEA20649.1 433 ALQGLQISQCtELTDDSIvdvIQTTPKLSHFDM-E-----D 467
                 677888886546776444443445999999998.3.....2 PP

  == domain 6  score: 13.3 bits;  conditional E-value: 3.4e-05
                 --EEE--SS.---E-S-HH...H-TT--EEE-.-S-----G CS
       LRR_4   3 LevLdLsnN.qltdiplle...klpnLkeLdLsgNnlitdl 39 
                 Le+L+ s +  + di+ l+   ++ +L++L + +N++++dl
  EEA20649.1 488 LEHLNVSYCdSIGDIGMLQvlkNCRQLRSLEM-DNTRVSDL 527
                 9******9989******776646999******.99888887 PP

>> PRANC  PRANC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.0   5.6e-07    0.0014      69      92 ..     165     188 ..     154     192 .. 0.84
   2 ?   -0.5   0.2      0.63   1.6e+03      52      72 ..     299     323 ..     287     327 .. 0.81

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 5.6e-07
       PRANC  69 kslWnlLPiEIkykIleyLndkdL 92 
                  + Wn +P+EIk kIl yL+ k++
  EEA20649.1 165 LDFWNDMPNEIKTKILGYLTPKEI 188
                 568*****************9998 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.63
       PRANC  52 ykliekaievlnnicsk....kslW 72 
                 ++ +++a++++ ++cs+    + +W
  EEA20649.1 299 STVTNSAMKIIAQTCSQletlNVSW 323
                 567899*********9986666666 PP

>> LRR_1  Leucine Rich Repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0       2.6   6.7e+03       3      11 ..     237     245 ..     236     262 .. 0.74
   2 ?   -2.5   0.0       5.9   1.5e+04       1       9 [.     289     297 ..     289     299 .. 0.85
   3 !    5.9   0.1      0.01        26       1      13 [.     315     327 ..     315     344 .. 0.77
   4 ?    3.5   0.0     0.062   1.6e+02       2      12 ..     408     418 ..     407     440 .. 0.82
   5 !    6.2   0.1    0.0082        21       2      14 ..     488     500 ..     487     527 .. 0.80

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 2.6
       LRR_1   3 rhLdLsnnp 11 
                 r L+L+++ 
  EEA20649.1 237 RDLNLRGCV 245
                 5699*9996 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 5.9
       LRR_1   1 nLrhLdLsn 9  
                 +L+++++s+
  EEA20649.1 289 SLKYINVSG 297
                 69****986 PP

  == domain 3  score: 5.9 bits;  conditional E-value: 0.01
       LRR_1   1 nLrhLdLsnnpll 13 
                 +L++L++s++ ++
  EEA20649.1 315 QLETLNVSWCLNI 327
                 59********983 PP

  == domain 4  score: 3.5 bits;  conditional E-value: 0.062
       LRR_1   2 LrhLdLsnnpl 12 
                 LrhLd+ ++ +
  EEA20649.1 408 LRHLDIHQCTN 418
                 9*****99986 PP

  == domain 5  score: 6.2 bits;  conditional E-value: 0.0082
       LRR_1   2 LrhLdLsnnpllg 14 
                 L+hL++s++  +g
  EEA20649.1 488 LEHLNVSYCDSIG 500
                 9********9833 PP

>> Phage_TTP_1  Phage tail tube protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   3.6e-05     0.093      59      96 ..     146     184 ..     140     189 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 3.6e-05
  Phage_TTP_1  59 ygnnkvkdvevgksapqvaltv.ndLpfdikqkllGrvs 96 
                   g+ +++dv+  + +++ +l++ nd+p++ik k+lG+ +
   EEA20649.1 146 EGDATIVDVQGKTRYTKRTLDFwNDMPNEIKTKILGYLT 184
                  6899999***99999999**955*************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (716 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       511  (0.0285013); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.64u 0.31s 00:00:00.95 Elapsed: 00:00:00.47
# Mc/sec: 4572.37
//
Query:       EEA20650.1  [L=320]
Description: nuclear protein involved in pre-rRNA processing, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-32  111.3  13.2    3.1e-32  111.3  13.2    2.7  3  Efg1      rRNA-processing protein Efg1
  ------ inclusion threshold ------
      0.066   12.2   0.4       0.12   11.4   0.4    1.4  1  TMEM232   Transmembrane protein family 232
        0.1   12.0   0.3        0.1   12.0   0.3    2.8  3  DUF4349   Domain of unknown function (DUF4349)


Domain annotation for each model (and alignments):
>> Efg1  rRNA-processing protein Efg1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.3  13.2   5.2e-36   3.1e-32       1     114 []      62     179 ..      62     179 .. 0.97
   2 ?   -3.0   0.3       1.6   9.3e+03      70      95 ..     194     219 ..     183     223 .. 0.49
   3 ?   -0.9   1.4      0.35   2.1e+03      26      34 ..     292     298 ..     270     314 .. 0.47

  Alignments for each domain:
  == domain 1  score: 111.3 bits;  conditional E-value: 5.2e-36
                 HHHHHHHHHHHHS-SS---SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HH....HHHHHHHHHHHHH CS
        Efg1   1 lkkkiRdlkRlLakkekLpaevreekereLkaleaeleeaekkekekklakkYhkvrFfErkKatRklkrlkkqleeledee....ekeelekkleele 95 
                 lk++iRd+kRlL++ e+L++e+r+ +er+Lk +e++le+++++++++++++kYh+vrF++rk at++l+ +++qle+++++e    + ++l+ k++ ++
  EEA20650.1  62 LKRRIRDVKRLLTRAENLSPEARIVQERALKGYERDLEQEQARRQRSEIIRKYHFVRFLDRKTATKQLRTAQRQLEKAKQQEedksKLAALQGKIDMAQ 160
                 79**************************************************************************988888777789999******** PP

                 HHHHHHHHS-TTS----SS CS
        Efg1  96 vdlnYvlyyPklekYisLy 114
                 +d+nY++yyP +ekY+sLy
  EEA20650.1 161 IDVNYTIYYPLTEKYLSLY 179
                 ******************9 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.6
                 HHHHHHHH---HHHHHHHHHHHHHHH CS
        Efg1  70 rlkkqleeledeeekeelekkleele 95 
                 ++  + ++ +de e+e++ +++++ e
  EEA20650.1 194 KVANTDDDDDDEGEEESVDEEMQTSE 219
                 33333333333336666666665555 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 0.35
                 HHHHHHHHH CS
        Efg1  26 kereLkale 34 
                 ke+  k  +
  EEA20650.1 292 KEK--KRKR 298
                 111..1111 PP

>> TMEM232  Transmembrane protein family 232
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.4   1.9e-05      0.12     341     405 ..     109     172 ..     100     198 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 1.9e-05
     TMEM232 341 selrktaligfldcksskkklelkdkseeekelkeaslldlleyfsskisdncdqviWiirYglv 405
                   +rk  +++fld k+  k+l++ +++ e+ +++e    +l   +++ki +   +v ++i+Y l 
  EEA20650.1 109 EIIRKYHFVRFLDRKTATKQLRTAQRQLEKAKQQEEDKSKLAA-LQGKIDMAQIDVNYTIYYPLT 172
                 468***********************99998888888776655.5999999999*******9876 PP

>> DUF4349  Domain of unknown function (DUF4349)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   2.4     0.012        71      78     140 ..      49     106 ..      36     110 .. 0.75
   2 ?   12.0   0.3   1.7e-05       0.1     107     156 ..     118     166 ..     112     192 .. 0.91
   3 ?   -1.4   0.1      0.23   1.3e+03     139     168 ..     263     292 ..     261     302 .. 0.81

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.012
     DUF4349  78 stsaeDVTeqyvDleaRlkaleasedrllallekaksvedlleiereLsevqaeieslegqlr 140
                 + s+ D   ++ Dl++R++  + + +r ++l  +a  v+     er+L+  + ++e+ +++++
  EEA20650.1  49 KNSTGDKGLSINDLKRRIRDVKRLLTRAENLSPEARIVQ-----ERALKGYERDLEQEQARRQ 106
                 566777888888888888888888888887766666554.....7888888888888888876 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 1.7e-05
     DUF4349 107 allekaksvedlleiereLsevqaeieslegqlryLdnqvaystvtvtlr 156
                  +l++++ ++ l +++r+L++ +++ e+ +++l++L++++++++++v+++
  EEA20650.1 118 RFLDRKTATKQLRTAQRQLEKAKQQ-EEDKSKLAALQGKIDMAQIDVNYT 166
                 589999999***********99988.999******************997 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.23
     DUF4349 139 lryLdnqvaystvtvtlrepeaeteaeeee 168
                 +r+Ld+  a+s v ++  +++aet++++e+
  EEA20650.1 263 IRSLDGTAATSNVVMNTGKEKAETTTNREK 292
                 589999999999999999999999888766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (320 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2622  (0.146244); expected 358.6 (0.02)
Passed bias filter:                      533  (0.0297284); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.73u 0.32s 00:00:01.05 Elapsed: 00:00:00.49
# Mc/sec: 1946.60
//
Query:       EEA20651.1  [L=1021]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      3e-17   63.0  16.4    2.4e-12   47.1   8.3    3.4  3  zinc_ribbon_16  Zinc-ribbon like family
     0.0022   18.2   0.4     0.0096   16.2   0.4    2.1  1  zf-rbx1         RING-H2 zinc finger domain
     0.0061   16.2   7.3     0.0061   16.2   7.3    2.9  4  Zn_ribbon_17    Zinc-ribbon, C4HC2 type
  ------ inclusion threshold ------
      0.017   14.7   0.4      0.035   13.8   0.4    1.4  1  HrpB1_HrpK      Bacterial type III secretion protein (HrpB1_H
       0.14   13.1   1.3          4    8.5   0.5    3.9  5  WD40            WD domain, G-beta repeat


Domain annotation for each model (and alignments):
>> zinc_ribbon_16  Zinc-ribbon like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0      0.68   2.4e+03       1      16 [.     836     851 ..     836     873 .. 0.66
   2 !   19.3   0.4   2.8e-07     0.001      36      62 ..     905     930 ..     874     957 .. 0.77
   3 !   47.1   8.3   6.8e-16   2.4e-12      82     123 ..     979    1020 ..     949    1021 .] 0.82

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.68
  zinc_ribbon_16   1 cnfckksitpfsakek 16 
                     cn+c +++    +   
      EEA20651.1 836 CNYCTRPLHQTGSIAS 851
                     9***999975444443 PP

  == domain 2  score: 19.3 bits;  conditional E-value: 2.8e-07
  zinc_ribbon_16  36 sksslcprcskplpkcavcglslGtsd 62 
                     s  ++cp+c +++p+c vc l lG+ d
      EEA20651.1 905 S-GTVCPKCFRHMPRCGVCSLWLGSPD 930
                     3.689*******************875 PP

  == domain 3  score: 47.1 bits;  conditional E-value: 6.8e-16
  zinc_ribbon_16   82 krfekwlsfclscghgahashakewfsthsicpvadcnceck 123 
                      +   +++ fc++c+hg ha+hak wf +h +cpva+c c c 
      EEA20651.1  979 EITRRFVVFCINCNHGFHANHAKAWFARHRVCPVAECTCVCD 1020
                      44567889*********************************6 PP

>> zf-rbx1  RING-H2 zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.4   2.7e-06    0.0096      25      53 ..     984    1012 ..     961    1014 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 2.7e-06
     zf-rbx1   25 cpvvlGeCgHaFHlhCiskWlktrkvCPl 53  
                   +v + +C+H FH +  + W+ +++vCP+
  EEA20651.1  984 FVVFCINCNHGFHANHAKAWFARHRVCPV 1012
                  4455569*********************7 PP

>> Zn_ribbon_17  Zinc-ribbon, C4HC2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.1       1.7   6.1e+03      32      47 ..     206     221 ..     196     222 .. 0.70
   2 ?   -4.5   0.8       4.8   1.7e+04      32      49 ..     577     592 ..     576     594 .. 0.51
   3 ?   -1.3   0.1      0.47   1.7e+03       5      15 ..     834     844 ..     830     849 .. 0.71
   4 !   16.2   7.3   1.7e-06    0.0061      15      54 ..     982    1020 ..     978    1021 .] 0.90

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 1.7
  Zn_ribbon_17  32 CarewfenddlaeCps 47 
                    a +w++++  a+C+s
    EEA20651.1 206 TAVDWLDENYFASCSS 221
                   3667888888888876 PP

  == domain 2  score: -4.5 bits;  conditional E-value: 4.8
  Zn_ribbon_17  32 CarewfenddlaeCpsGC 49 
                   C  + +e+ +   C   C
    EEA20651.1 577 CETDFWEHRQ--LCLHIC 592
                   5555555554..454444 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.47
  Zn_ribbon_17   5 ksCayCelavk 15 
                    +C+yC  +++
    EEA20651.1 834 LTCNYCTRPLH 844
                   58999986665 PP

  == domain 4  score: 16.2 bits;  conditional E-value: 1.7e-06
  Zn_ribbon_17   15 kgrvvlcgvCeHvlHasCarewfenddlaeCps.GCGckcl 54  
                    ++ vv+c +C+H  Ha+ a++wf      +Cp+  C c c 
    EEA20651.1  982 RRFVVFCINCNHGFHANHAKAWFARHR--VCPVaECTCVCD 1020
                    567899*******************99..***989***995 PP

>> HrpB1_HrpK  Bacterial type III secretion protein (HrpB1_HrpK)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.4   9.7e-06     0.035      51     119 ..     617     685 ..     609     690 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 9.7e-06
  HrpB1_HrpK  51 egvlliergrweeAlrlLreveaeasgtpyakaLlAlcLaalrDeeWrayAeevlesdadpdalaLvka 119
                  + l+i +++ + A ++Lr  e ++ +  +a a++  +  ++ D++W    +e+  + +dp a+a+++ 
  EEA20651.1 617 AAALAIFQNEAKIAFHALRRNEPTQAHKLLAMAIVGAAKGQQSDKDWEETCNEIATELTDPYARAVLAL 685
                 68899********************************************************99998765 PP

>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       2.6   9.2e+03      15      32 ..     102     117 ..      96     138 .. 0.66
   2 ?   -1.7   0.0       1.8   6.4e+03       4      29 ..     152     177 ..     150     186 .. 0.56
   3 ?    8.5   0.5    0.0011         4      13      38 .]     203     231 ..     192     231 .. 0.69
   4 ?   -3.0   0.0       4.7   1.7e+04      13      36 ..     265     289 ..     257     291 .. 0.57
   5 ?   -1.8   0.0         2   7.2e+03       4      18 ..     542     556 ..     539     560 .. 0.76

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 2.6
                 EEEEETTSSEEEEEETTS CS
        WD40  15 slafspdgawlasGsdDg 32 
                 ++afs++g +  +G+ D+
  EEA20651.1 102 AVAFSSHGLL--AGGLDK 117
                 5666666655..355443 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 1.8
                 EEEEESSSSEEEEE.EETTSSEEEEEE CS
        WD40   4 lrtltGHssvtsla.fspdgawlasGs 29 
                 lr+l+   ++ts++ f    + l++G 
  EEA20651.1 152 LRKLSSD-PITSIKfFREQPDTLVAGV 177
                 5666544.6999984333334466665 PP

  == domain 3  score: 8.5 bits;  conditional E-value: 0.0011
                 E..EEEEEETTSSEEEEE..ETTSEEEEEE CS
        WD40  13 v..tslafspdgawlasG..sdDgtvriWd 38 
                 v  t++++ +++ + as+  s D tv +Wd
  EEA20651.1 203 VhnTAVDWLDENYF-ASCssSADATVCLWD 231
                 54467867766666.5552368*******9 PP

  == domain 4  score: -3.0 bits;  conditional E-value: 4.7
                 EEEEEEETTSSE...EEEEETTSEEEE CS
        WD40  13 vtslafspdgaw...lasGsdDgtvri 36 
                 ++sl+fs+ ++    ++ +s +g  ++
  EEA20651.1 265 IWSLRFSRTKRGclgVL-SS-NGQFKM 289
                 88888877766522222.24.665555 PP

  == domain 5  score: -1.8 bits;  conditional E-value: 2
                 EEEEESSSSEEEEEE CS
        WD40   4 lrtltGHssvtslaf 18 
                  ++l+ Hss++ ++ 
  EEA20651.1 542 SKELRQHSSINKIDL 556
                 678999*99*99854 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1021 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1189  (0.0663171); expected 358.6 (0.02)
Passed bias filter:                      728  (0.0406046); expected 358.6 (0.02)
Passed Vit filter:                        69  (0.00384851); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.88u 0.30s 00:00:01.18 Elapsed: 00:00:00.49
# Mc/sec: 6247.07
//
Query:       EEA20652.1  [L=126]
Description: snRNP and snoRNP protein (Snu13), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.2e-26   90.5   0.1    5.1e-26   90.3   0.1    1.1  1  Ribosomal_L7Ae  Ribosomal protein L7Ae/L30e/S12e/Gadd45 famil
    0.00092   19.3   0.0    0.00099   19.2   0.0    1.2  1  RNase_P_pop3    RNase P subunit Pop3
     0.0017   18.2   0.0     0.0025   17.6   0.0    1.3  1  PELOTA_1        PELOTA RNA binding domain


Domain annotation for each model (and alignments):
>> Ribosomal_L7Ae  Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.3   0.1   8.5e-30   5.1e-26       2      92 ..      19     109 ..      18     111 .. 0.97

  Alignments for each domain:
  == domain 1  score: 90.3 bits;  conditional E-value: 8.5e-30
                     HHHHHHHHHHHHTEEEESHHHHHHHHHTTTESEEEEETTSSSGGHHHHHHHHHHHTTEEEEEESCHHHHHHHTTSSSECSEEEEEESTTTH CS
  Ribosomal_L7Ae   2 aieevlkkakkagklvlGlkevtkalergeaklvilAedvepeekkkllealckekevpyvkvkskkeLGelvgkkrpvsalaikdegdsk 92 
                     +i +v+++a++ ++l++G++e+tk+l+rg+ +++ilA+d++p  +  +l+ lc++k+vpy++v+sk +LG++ g +rpv+a++i+++++s+
      EEA20652.1  19 NILDVVQQASHYKQLKKGANEATKTLNRGTSEIIILAADTTPLAILLHLPLLCEDKNVPYCYVPSKLALGRATGVSRPVIAVSITTNDASD 109
                     67899**********************************************************************************9886 PP

>> RNase_P_pop3  RNase P subunit Pop3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   0.0   1.7e-07   0.00099      31     108 ..       9      81 ..       4     126 .] 0.71

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 1.7e-07
  RNase_P_pop3  31 leLlqekvlkklvrlleskeneeseltvglneivelLecsesddvvllvcnkD.tPsvLlsqlpllvavanltvklvql 108
                   + + +e++ ++++ + + +  + ++l  g ne  + L+  +  ++++l+   D tP+ +l +lpll++ +n  v+   +
    EEA20652.1   9 WPVADEALTQNILDVVQ-QASHYKQLKKGANEATKTLN-RGTSEIIILA--ADtTPLAILLHLPLLCEDKN--VPYCYV 81 
                   55567777777777777.67778899************.6666665555..5545***************9..444444 PP

>> PELOTA_1  PELOTA RNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   4.2e-07    0.0025      16      70 ..      27      83 ..      15      93 .. 0.86

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 4.2e-07
    PELOTA_1 16 iedinliKPgigEaTRvlLRRvPekvlvrdeee..pdlahlllLakekgvpveevpd 70
                 ++++  K g  EaT+ l R + e ++++++++  + l hl lL+++k+vp+  vp+
  EEA20652.1 27 ASHYKQLKKGANEATKTLNRGTSEIIILAADTTplAILLHLPLLCEDKNVPYCYVPS 83
                567788999**************999999988855678999**********988875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (126 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       607  (0.0338558); expected 358.6 (0.02)
Passed bias filter:                      516  (0.0287802); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.43u 0.30s 00:00:00.73 Elapsed: 00:00:00.46
# Mc/sec: 831.96
//
Query:       EEA20653.1  [L=717]
Description: Ku family DNA helicase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.1e-38  132.0   0.1    2.8e-38  130.8   0.1    1.7  1  Ku_PK_bind  Ku C terminal domain like
    1.3e-32  113.1   0.0    2.2e-32  112.4   0.0    1.4  1  Ku          Ku70/Ku80 beta-barrel domain
    5.6e-13   49.1   0.0    1.3e-12   48.0   0.0    1.6  1  Ku_N        Ku70/Ku80 N-terminal alpha/beta domain
     0.0048   17.6   2.0     0.0076   16.9   0.5    2.2  2  Ku_C        Ku70/Ku80 C-terminal arm
  ------ inclusion threshold ------
      0.011   16.0   0.1      0.029   14.6   0.1    1.8  1  VWA         von Willebrand factor type A domain


Domain annotation for each model (and alignments):
>> Ku_PK_bind  Ku C terminal domain like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  130.8   0.1   7.7e-42   2.8e-38       1     120 []     593     713 ..     593     713 .. 0.98

  Alignments for each domain:
  == domain 1  score: 130.8 bits;  conditional E-value: 7.7e-42
  Ku_PK_bind   1 dPvedFkkllaqkdeedlvekavkqlksvIeqlvedslgdssydkaveclkalReeaieeeepelyNdFlrdlkkklqs.e.ggdrrefWkelvkkekl 97 
                 +++++Fk++la+++  +++++a++q++++Ie+ +++s+gds+yd++ve l +lRee+i++eep lyN+F++ lk+k+++ + ggdr+e+W+ l++++k+
  EEA20653.1 593 NAIPEFKQMLATAETVETIKDATSQMQKIIEDHIRTSFGDSNYDRVVEELGVLREELIDYEEPGLYNEFVQPLKEKILTeKlGGDRQELWW-LIRRSKI 690
                 579************9***************************************************************77*********7.******* PP

  Ku_PK_bind  98 glIskdeaessdvteeeAkeFlk 120
                 glI+k ++++s+v+eeeAk+Fl+
  EEA20653.1 691 GLIDKATSDQSEVSEEEAKQFLS 713
                 *********************95 PP

>> Ku  Ku70/Ku80 beta-barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.4   0.0   6.1e-36   2.2e-32       5     187 ..     241     449 ..     238     467 .. 0.80

  Alignments for each domain:
  == domain 1  score: 112.4 bits;  conditional E-value: 6.1e-36
          Ku   5 vsipVklykateeakkpkfkkldketne.....................pvkvetkyvcsdtg..................evdeedivkgyeyGgevv 64 
                 ++i+V+ y +t  ak+p+ + +  +t+                                                      e++++++ kgyeyG++ v
  EEA20653.1 241 LRIQVERYYRTYVAKPPSTSSFVVKTGGdasqpstqtleaskdadanltS------------VrnvrtyhvddpqvvggkrELERDELAKGYEYGRTAV 327
                 789*************9999977777776666555555555555555553............04444444444557888866***************** PP

          Ku  65 pltkeelekiksfdskglkllgFvplseilkeylsikssyfiyPddkdekgstkafsaLveamleskkvaivrfvlrskskprlvaLvPqeeelsseee 163
                 p+++ + +  k  +   l+l+gF++++  +++  ++  s++i++++ +ek++  a+s+L++a+ e++++ai+r+v ++  +p +v L P    ++ ++ 
  EEA20653.1 328 PISESDENITKLETMAALELIGFIQADHYDRFMNMS-TSNVIIAQKTNEKAAL-ALSSLIHALFELDCYAIARLVTKDGKSPLIVLLAPL---IDPDY- 420
                 ********5455669***********9966666655.*******999999777.************************************...87876. PP

          Ku 164 keglvlvtLpfaddiRslkfpsl......d 187
                  e+l+ v+Lpf++d+Rs+kfp+l      +
  EEA20653.1 421 -ECLLEVQLPFSEDVRSYKFPPLdrvitiS 449
                 .8*********************6555442 PP

>> Ku_N  Ku70/Ku80 N-terminal alpha/beta domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.0   0.0   3.6e-16   1.3e-12       1     158 [.       6     160 ..       6     185 .. 0.91

  Alignments for each domain:
  == domain 1  score: 48.0 bits;  conditional E-value: 3.6e-16
                 EEEEEEE-SHHHHCTTCCSCC.HHHHHHHHHHHHHHHHHHCTCS.EEEEEEEESSSSTBS....TTTCTTEEEEEECCCHHHHHHHHHHCCHHHCCHHH CS
        Ku_N   1 avvfviDvspaMfesskeees.pfelalkciaellkrkvisrsk.DlIavvlygtdesen....keqlenitvlreldlpdaellkelkqivesedasv 93 
                 a+v+++Dv+++M + +++     ++ a+ ++ + ++  v + +k   I+vv   tde++     +e++eni v++ l +  +  + +l + +++     
  EEA20653.1   6 ATVYIVDVGKSMKQHNNGRDIsDLDWAMRYVWDKITTTVATGRKtATIGVVGLKTDETKVpledDEGYENISVMQGLGQMLMPDIRRLREEIKP----- 99 
                 69**************999988**********************889************9**********************************..... PP

                 HCCCTTSS-TTHHHHHHHHHHHHHHTTSSES.EEEEEEEESSSSTCCGHHHHHHHHHHHHHHHHHH CS
        Ku_N  94 eglaedssqasllsaLivclellqkvgkkls.kkriflftdlddpfedsdklelilqklkakDlrd 158
                     ++  +++  s+Liv++++++  +kkl+ k++i l+t+      +sd le i  klka +++ 
  EEA20653.1 100 ----SETDEGDAISSLIVAIQMINVYTKKLKyKRKIYLVTNGKGAI-SSDGLEDIASKLKADNIEL 160
                 ....99999****************788877256688888877766.************9988775 PP

>> Ku_C  Ku70/Ku80 C-terminal arm
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.5   2.1e-06    0.0076      10      88 .]     498     589 ..     495     589 .. 0.77
   2 ?   -2.6   0.0       2.6   9.2e+03      22      38 ..     602     617 ..     593     627 .. 0.49

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 2.1e-06
                 HHHHHHHHHHHHHHTT---.......---SS--HHHHHHHHH-....HHHHHHHHHHHHH..HHHHH......---T...........HHHHHHH CS
        Ku_C  10 PsLqrhykiLqalAldedlpe.....eledktlpkyeaidkragslleewkelfeleeedkekkkekrkaededeep...........aakkaki 88 
                 P L r  ++   +A+++d+p      +l  + +p+ +++++ra+++l+ + ++ + ++  ++ k+ kr +  + ++p           ++k+aki
  EEA20653.1 498 PLLHRIEQAVRWRAIHPDEPVpppseRLTRLSKPP-KEVQERAQKYLDRIIRAADVKKVPPKAKGRKRNR--DVDKPlsgldidellhREKRAKI 589
                 7788888899999******9889995666666666.**********************998655555444..46666666666667777787775 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 2.6
                 HHTT---..---SS--H CS
        Ku_C  22 lAldedlpeeledktlp 38 
                 lA+ e++ e+++d t +
  EEA20653.1 602 LATAETV-ETIKDATSQ 617
                 3333333.344444444 PP

>> VWA  von Willebrand factor type A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.1     8e-06     0.029      76     148 ..     100     190 ..      10     205 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 8e-06
                 GSSC-HHHHHHHHHHHHHHHHGTSST.TSEEEEEEEESS--CSS..HTHHHHHHHHGCTEEEEEEEE................SSSHHHHHH CS
         VWA  76 ggttntgkalkyaleklfkssagaRe.nakkviilltdGksndg..dpkeaaneakeqgikvfavGv................gnadekelL 148
                 ++t+  g+a++ ++  ++  +   ++ ++k+ i l+t Gk   +   +++ a ++k+++i+++++Gv                g+a +++lL
  EEA20653.1 100 SETD-EGDAISSLIVAIQMINVYTKKlKYKRKIYLVTNGKGAISsdGLEDIASKLKADNIELIVLGVdfddpdygfkeedkdeGKAENEALL 190
                 4444.555555555422222222223489*********99844335*********************7766666666555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (717 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       617  (0.0344135); expected 358.6 (0.02)
Passed bias filter:                      491  (0.0273858); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.64u 0.27s 00:00:00.91 Elapsed: 00:00:00.43
# Mc/sec: 4967.42
//
Query:       EEA20654.1  [L=722]
Description: Ku family DNA helicase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    6.3e-37  126.4   0.1    1.6e-36  125.0   0.1    1.7  1  Ku_PK_bind  Ku C terminal domain like
    1.4e-32  113.1   0.0    2.4e-32  112.3   0.0    1.3  1  Ku          Ku70/Ku80 beta-barrel domain
    5.8e-13   49.1   0.0    1.3e-12   48.0   0.0    1.6  1  Ku_N        Ku70/Ku80 N-terminal alpha/beta domain
     0.0049   17.5   2.0     0.0076   16.9   0.5    2.2  2  Ku_C        Ku70/Ku80 C-terminal arm
  ------ inclusion threshold ------
      0.011   16.0   0.1      0.029   14.6   0.1    1.8  1  VWA         von Willebrand factor type A domain


Domain annotation for each model (and alignments):
>> Ku_PK_bind  Ku C terminal domain like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  125.0   0.1   4.6e-40   1.6e-36       1     117 [.     593     710 ..     593     712 .. 0.97

  Alignments for each domain:
  == domain 1  score: 125.0 bits;  conditional E-value: 4.6e-40
  Ku_PK_bind   1 dPvedFkkllaqkdeedlvekavkqlksvIeqlvedslgdssydkaveclkalReeaieeeepelyNdFlrdlkkklqs.e.ggdrrefWkelvkkekl 97 
                 +++++Fk++la+++  +++++a++q++++Ie+ +++s+gds+yd++ve l +lRee+i++eep lyN+F++ lk+k+++ + ggdr+e+W+ l++++k+
  EEA20654.1 593 NAIPEFKQMLATAETVETIKDATSQMQKIIEDHIRTSFGDSNYDRVVEELGVLREELIDYEEPGLYNEFVQPLKEKILTeKlGGDRQELWW-LIRRSKI 690
                 579************9***************************************************************77*********7.******* PP

  Ku_PK_bind  98 glIskdeaessdvteeeAke 117
                 glI+k ++++s+v+eeeAk+
  EEA20654.1 691 GLIDKATSDQSEVSEEEAKQ 710
                 ******************98 PP

>> Ku  Ku70/Ku80 beta-barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.3   0.0   6.8e-36   2.4e-32       5     187 ..     241     449 ..     238     466 .. 0.80

  Alignments for each domain:
  == domain 1  score: 112.3 bits;  conditional E-value: 6.8e-36
          Ku   5 vsipVklykateeakkpkfkkldketne.....................pvkvetkyvcsdtg..................evdeedivkgyeyGgevv 64 
                 ++i+V+ y +t  ak+p+ + +  +t+                                                      e++++++ kgyeyG++ v
  EEA20654.1 241 LRIQVERYYRTYVAKPPSTSSFVVKTGGdasqpstqtleaskdadanltS------------VrnvrtyhvddpqvvggkrELERDELAKGYEYGRTAV 327
                 789*************9999977777776666555555555555555553............04444444444557888866***************** PP

          Ku  65 pltkeelekiksfdskglkllgFvplseilkeylsikssyfiyPddkdekgstkafsaLveamleskkvaivrfvlrskskprlvaLvPqeeelsseee 163
                 p+++ + +  k  +   l+l+gF++++  +++  ++  s++i++++ +ek++  a+s+L++a+ e++++ai+r+v ++  +p +v L P    ++ ++ 
  EEA20654.1 328 PISESDENITKLETMAALELIGFIQADHYDRFMNMS-TSNVIIAQKTNEKAAL-ALSSLIHALFELDCYAIARLVTKDGKSPLIVLLAPL---IDPDY- 420
                 ********5455669***********9966666655.*******999999777.************************************...87876. PP

          Ku 164 keglvlvtLpfaddiRslkfpsl......d 187
                  e+l+ v+Lpf++d+Rs+kfp+l      +
  EEA20654.1 421 -ECLLEVQLPFSEDVRSYKFPPLdrvitiS 449
                 .8*********************5554432 PP

>> Ku_N  Ku70/Ku80 N-terminal alpha/beta domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.0   0.0   3.6e-16   1.3e-12       1     158 [.       6     160 ..       6     185 .. 0.91

  Alignments for each domain:
  == domain 1  score: 48.0 bits;  conditional E-value: 3.6e-16
                 EEEEEEE-SHHHHCTTCCSCC.HHHHHHHHHHHHHHHHHHCTCS.EEEEEEEESSSSTBS....TTTCTTEEEEEECCCHHHHHHHHHHCCHHHCCHHH CS
        Ku_N   1 avvfviDvspaMfesskeees.pfelalkciaellkrkvisrsk.DlIavvlygtdesen....keqlenitvlreldlpdaellkelkqivesedasv 93 
                 a+v+++Dv+++M + +++     ++ a+ ++ + ++  v + +k   I+vv   tde++     +e++eni v++ l +  +  + +l + +++     
  EEA20654.1   6 ATVYIVDVGKSMKQHNNGRDIsDLDWAMRYVWDKITTTVATGRKtATIGVVGLKTDETKVpledDEGYENISVMQGLGQMLMPDIRRLREEIKP----- 99 
                 69**************999988**********************889************9**********************************..... PP

                 HCCCTTSS-TTHHHHHHHHHHHHHHTTSSES.EEEEEEEESSSSTCCGHHHHHHHHHHHHHHHHHH CS
        Ku_N  94 eglaedssqasllsaLivclellqkvgkkls.kkriflftdlddpfedsdklelilqklkakDlrd 158
                     ++  +++  s+Liv++++++  +kkl+ k++i l+t+      +sd le i  klka +++ 
  EEA20654.1 100 ----SETDEGDAISSLIVAIQMINVYTKKLKyKRKIYLVTNGKGAI-SSDGLEDIASKLKADNIEL 160
                 ....99999****************788877256688888877766.************9988775 PP

>> Ku_C  Ku70/Ku80 C-terminal arm
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.5   2.1e-06    0.0076      10      88 .]     498     589 ..     495     589 .. 0.77
   2 ?   -2.6   0.0       2.6   9.3e+03      22      38 ..     602     617 ..     593     627 .. 0.49

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 2.1e-06
                 HHHHHHHHHHHHHHTT---.......---SS--HHHHHHHHH-....HHHHHHHHHHHHH..HHHHH......---T...........HHHHHHH CS
        Ku_C  10 PsLqrhykiLqalAldedlpe.....eledktlpkyeaidkragslleewkelfeleeedkekkkekrkaededeep...........aakkaki 88 
                 P L r  ++   +A+++d+p      +l  + +p+ +++++ra+++l+ + ++ + ++  ++ k+ kr +  + ++p           ++k+aki
  EEA20654.1 498 PLLHRIEQAVRWRAIHPDEPVpppseRLTRLSKPP-KEVQERAQKYLDRIIRAADVKKVPPKAKGRKRNR--DVDKPlsgldidellhREKRAKI 589
                 7788888899999******9889995666666666.**********************998655555444..46666666666667777787775 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 2.6
                 HHTT---..---SS--H CS
        Ku_C  22 lAldedlpeeledktlp 38 
                 lA+ e++ e+++d t +
  EEA20654.1 602 LATAETV-ETIKDATSQ 617
                 3333333.344444444 PP

>> VWA  von Willebrand factor type A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.1   8.1e-06     0.029      76     148 ..     100     190 ..      10     205 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 8.1e-06
                 GSSC-HHHHHHHHHHHHHHHHGTSST.TSEEEEEEEESS--CSS..HTHHHHHHHHGCTEEEEEEEE................SSSHHHHHH CS
         VWA  76 ggttntgkalkyaleklfkssagaRe.nakkviilltdGksndg..dpkeaaneakeqgikvfavGv................gnadekelL 148
                 ++t+  g+a++ ++  ++  +   ++ ++k+ i l+t Gk   +   +++ a ++k+++i+++++Gv                g+a +++lL
  EEA20654.1 100 SETD-EGDAISSLIVAIQMINVYTKKlKYKRKIYLVTNGKGAISsdGLEDIASKLKADNIELIVLGVdfddpdygfkeedkdeGKAENEALL 190
                 4444.555555555422222222223489*********99844335*********************7766666666555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (722 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       625  (0.0348597); expected 358.6 (0.02)
Passed bias filter:                      505  (0.0281667); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.66u 0.29s 00:00:00.95 Elapsed: 00:00:00.45
# Mc/sec: 4814.25
//
Query:       EEA20655.1  [L=176]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-26   92.1   1.5    2.3e-26   92.1   1.5    1.5  2  DUF4149   Domain of unknown function (DUF4149)


Domain annotation for each model (and alignments):
>> DUF4149  Domain of unknown function (DUF4149)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.1   1.5   1.3e-30   2.3e-26       1     101 [.      10     119 ..      10     120 .. 0.97
   2 ?   -2.2   0.0      0.29   5.1e+03      40      57 ..     148     165 ..     135     172 .. 0.57

  Alignments for each domain:
  == domain 1  score: 92.1 bits;  conditional E-value: 1.3e-30
     DUF4149   1 lslglllGsqlwvtfvvapvlfrsLprhqfgelqsklFplyfglglalsvlllltevavg........seklasee.llqlllllvvllltllnafyle 90 
                 ls+g+llG+q++++f+ + v+f++Lpr+qf++lq+klFp+yf l++al++ l+lt++ ++        s+  a e+  + ll+l+++ +++l+n+fyl+
  EEA20655.1  10 LSYGTLLGAQIYQSFIGGTVAFKALPRPQFSALQNKLFPIYFSLQSALPLALALTFPGKFgtsdlssiSGVFADENrYAVLLPLTIISVVGLVNMFYLT 108
                 79********************************************************99********9999999989999****************** PP

     DUF4149  91 pritslkeqre 101
                 p + ++ ++r+
  EEA20655.1 109 PLVGKVIKERF 119
                 ***99988886 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.29
     DUF4149  40 lyfglglalsvlllltev 57 
                 ++ gl+++l + +l+ ++
  EEA20655.1 148 KLHGLSSLLNMGALIATI 165
                 444444444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (176 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       342  (0.0190752); expected 358.6 (0.02)
Passed bias filter:                      283  (0.0157845); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.36u 0.22s 00:00:00.57 Elapsed: 00:00:00.36
# Mc/sec: 1469.52
//
Query:       EEA20656.1  [L=629]
Description: MFS sugar transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-90  304.3  27.9    1.8e-90  304.0  27.9    1.1  1  Sugar_tr  Sugar (and other) transporter
    1.6e-17   63.5  27.6    1.6e-17   63.5  27.6    2.0  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.076   13.2   5.3        4.7    7.5   0.0    3.8  5  TrbC      TrbC/VIRB2 family
       0.38   11.2   2.0       0.51   10.7   0.1    2.2  2  DUF2663   Protein of unknown function (DUF2663)
        1.3    8.6   3.8        2.4    7.7   0.2    2.5  2  DUF1700   Protein of unknown function (DUF1700)
        3.3    7.6   6.2       0.93    9.3   0.2    3.1  3  DUF2427   Domain of unknown function (DUF2427)


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  304.0  27.9     6e-94   1.8e-90       2     452 .]     130     585 ..     129     585 .. 0.94

  Alignments for each domain:
  == domain 1  score: 304.0 bits;  conditional E-value: 6e-94
                 HHHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHH.HHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTT CS
    Sugar_tr   2 alvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaii.GslfagllgdrfGRkkslliaavlfvigavlqaaakgk 99 
                 +++ +++  ++g d  v +++++++   +n g +++ s k+ ++  +gliv++ ++ ++i G+ ++ +l  +f R+ ++ ia++++ ++++  ++a+  
  EEA20656.1 130 VIMCSMAAAVQGMDETVNNGAQAIYL--RNLGINTRFSGKQ-LDDITGLIVGAPYLCCAIlGCWLTEPLNRYFARRGTIFIACFFAAVCSIWEGVAN-- 223
                 57888999999**********99999..8888888888776.5889999999988887544************************************.. PP

                 SS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHH CS
    Sugar_tr 100 nsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPryl 198
                  ++  l+++R+++G+g+G  s +vP+y++E +p+ +Rgalv+++q++++fGi+++ i+g+++   s++  wr++lg+++v++ll+++ ++++PESPr+l
  EEA20656.1 224 -TWVNLFIARFFLGLGIGPKSSTVPIYAAECSPAPIRGALVMMWQMWTAFGIMLGNIMGVAFMSLSDDLSWRLMLGSTVVLPLLVCVQVYMCPESPRWL 321
                 .9************************************************************999998******************************* PP

                 HHTT-HHHHHHHHHHHHHC...HHHHHHHHHHHHHHHHHHH.....HTTHHHHSH......HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH.. CS
    Sugar_tr 199 vekgkeeeakevlaklrge...edadrelaeekdsleaeqeeekaswkellsskt...vrqrlligvvlqifqqltGinaimyysptifenlglsks.. 289
                 +++++ e+a ++++klr     + +d + a    ++e+e ++ k++  ++++ +t   +r++++    ++++qq++G+n+i yys+tif + g+s +  
  EEA20656.1 322 IQHDQVEKAFRSFRKLRSHdiqAARDLYYAYVLVQIEREINKGKNFFTMFMELFTvgrNRRATIGSWIVMFMQQFCGVNVIAYYSTTIFTTSGYSIQsa 420
                 ***************999877788899999999999999999999999999999998677777777888999**********************99889 PP

                 HHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS......CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHH CS
    Sugar_tr 290 llvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgivalllvaks...kaasivaivfialfialfalgwgpvpwvlvsElfpqsvRs 385
                 ll+++++g++n+v+ + a f++d fGRR+lll+ + + aic++  g   +++++ +   k    +++++++lf +++++g gp+p+ +++E fp++vR 
  EEA20656.1 421 LLASMGTGILNWVFALPATFTIDTFGRRNLLLTTFPFLAICLLWTG-FSFWIEQDNpfsKKRVAMVTTGMYLFEIFYSPGEGPIPFTYSAEAFPLHVRE 518
                 *********************************************9.888888888998777888899******************************* PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 386 kalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 ++++ a+a+ w +nf+ s++ p ++ + +  + f  +a+ ++++ + v+ff+petk +tlee++++f
  EEA20656.1 519 VGMSWATATCWCFNFILSFTWPSLLTSFKPQGAFGWYAAWCIIGWFLVLFFLPETKALTLEELDQVF 585
                 ****************************************************************997 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.5  27.6   5.2e-21   1.6e-17       3     351 ..     135     535 ..     133     537 .. 0.82
   2 !   14.0  23.7   5.8e-06     0.017       8     180 ..     390     576 ..     383     609 .. 0.72

  Alignments for each domain:
  == domain 1  score: 63.5 bits;  conditional E-value: 5.2e-21
       MFS_1   3 laaflsalarsilgpalplalaedlgispse........igllltlyalgaavaslpl.GrlsdrfGrrr.vlllglllfalglllllfasslw.lllv 90 
                 +aa++ +++ ++ + a   ++ ++lgi+  +         gl++++ +l +a++   l  +l   f +rr +++++ ++ a+++++  + ++ w  l++
  EEA20656.1 135 MAAAVQGMDETVNNGAQA-IYLRNLGINTRFsgkqlddiTGLIVGAPYLCCAILGCWLtEPLNRYF-ARRgTIFIACFFAAVCSIWEGV-ANTWvNLFI 230
                 677888888888888888.56688886555555667777999999999999999999945555557.6665999999999999333334.999989*** PP

       MFS_1  91 lrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg...Wravfyilaivsllafvlfllllpeepperkrkspke 186
                 +r++ Glg g   +++ +++a+ +p + rg  + ++++ +++G++lg + g +++s+     Wr++     ++ ll++v    ++++++++r+   + +
  EEA20656.1 231 ARFFLGLGIGPKSSTVPIYAAECSPAPIRGALVMMWQMWTAFGIMLGNIMGVAFMSLSDdlsWRLMLGSTVVLPLLVCV---QVYMCPESPRWLIQHDQ 326
                 ****************************************************8885444777***************99...78889999999999988 PP

       MFS_1 187 ee...............................kgtgpaplvp....awkallkdpvlw.illialllfffgfsglltllplylqevlglsglllagll 249
                  e                               +  +++++++    +++  ++++    ++++++   f+g++ + ++++++  ++ g+s   +a+l+
  EEA20656.1 327 VEkafrsfrklrshdiqaardlyyayvlvqierEINKGKNFFTmfmeLFTVGRNRRATIgSWIVMFMQQFCGVNVIAYYSTTI-FTTSGYS-IQSALLA 423
                 889999999999999999999999999888877666666666644433333333443337999999999*************7.999****.6777777 PP

       MFS_1 250 lallalvgailallagrlsdrlgrrrrlllallllllaalglallavt........ssavllllvlvliGfglgfv.fpsllalasdlappeeagtasg 339
                 ++ +++++ ++al a++ +d +grr+ ll ++++l++++l   +  ++        +  +++  +++l+ ++++    p+ +++ ++ +p + +   ++
  EEA20656.1 424 SMGTGILNWVFALPATFTIDTFGRRNLLLTTFPFLAICLLWTGFSFWIeqdnpfskKRVAMVTTGMYLFEIFYSPGeGPIPFTYSAEAFPLHVREVGMS 522
                 88888999999************************9999999999999999888544444444488888885555569********************* PP

       MFS_1 340 lfn.tagslggal 351
                 +++ t++++  +l
  EEA20656.1 523 WATaTCWCFNFIL 535
                 ***9***987665 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 5.8e-06
       MFS_1   8 salarsilgpalpl....alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa...........sslwlllvl 91 
                 ++++  + g+++      ++ ++ g+s +++ l+  + +++ +v++lp+ + +d fGrr +ll+++ ++a++ll+  f+             + ++  +
  EEA20656.1 390 VMFMQQFCGVNVIAyystTIFTTSGYSIQSALLASMGTGILNWVFALPATFTIDTFGRRNLLLTTFPFLAICLLWTGFSfwieqdnpfskKRVAMVTTG 488
                 3333333333333220016666667888888888888999********************************555556333354444444446666666 PP

       MFS_1  92 rvlqGlga.galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperk 180
                   l  +++  +  p+  ++ a+ fp   r  ++++++a+  +   +     + l++s+  +++f   a+ ++++  l+l++lpe+  +  
  EEA20656.1 489 MYLFEIFYsPGEGPIPFTYSAEAFPLHVREVGMSWATATCWCFNFILSFTWPSLLTSFKPQGAFGWYAAWCIIGWFLVLFFLPET--KAL 576
                 6677777758889*************************777777666677777777******************88755665554..444 PP

>> TrbC  TrbC/VIRB2 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0       1.2   3.6e+03      11      45 ..     119     153 ..     112     156 .. 0.58
   2 ?   -2.9   0.1       2.7   8.2e+03      61      85 ..     154     178 ..     135     185 .. 0.71
   3 ?    4.4   1.4     0.014        42      36      81 ..     256     298 ..     223     307 .. 0.75
   4 ?    7.5   0.0    0.0016       4.7      55      89 ..     455     492 ..     446     493 .. 0.90
   5 ?   -3.9   0.0       5.5   1.6e+04      27      49 ..     513     534 ..     511     536 .. 0.74

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 1.2
        TrbC  11 lllalalalvllllaspalAqaaggdpvetvlqni 45 
                 ++  ++ + +l+++ s a A ++  + v++ +q+i
  EEA20656.1 119 KWHQPWQLYWLVIMCSMAAAVQGMDETVNNGAQAI 153
                 55555566666666666665332226666666655 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 2.7
        TrbC  61 aiivaGimlafgrlswrtlvmvviG 85 
                  +  +Gi   f +++++++ ++++G
  EEA20656.1 154 YLRNLGINTRFSGKQLDDITGLIVG 178
                 5555677777888888888888887 PP

  == domain 3  score: 4.4 bits;  conditional E-value: 0.014
        TrbC  36 dpvetvlqnivdfltgplakviatiaiivaGimlafgrlswrtlvm 81 
                 +p+ ++l  + ++ t   a++i++  i+++++m +  +lswr +++
  EEA20656.1 256 APIRGALVMMWQMWT---AFGIMLGNIMGVAFMSLSDDLSWRLMLG 298
                 555555555555554...59*********************98775 PP

  == domain 4  score: 7.5 bits;  conditional E-value: 0.0016
        TrbC  55 kviatiaiivaGimlafgrls...wrtlvmvviGivii 89 
                 ++   i+++++G+ ++  +++   +++++mv  G+ ++
  EEA20656.1 455 FPFLAICLLWTGFSFWIEQDNpfsKKRVAMVTTGMYLF 492
                 67889**************99**9*******9998775 PP

  == domain 5  score: -3.9 bits;  conditional E-value: 5.5
        TrbC  27 palAqaaggdpvetvlqnivdfl 49 
                 p +  + g +++ t+ ++  +f+
  EEA20656.1 513 PLHVREVG-MSWATATCWCFNFI 534
                 56666676.99999999988876 PP

>> DUF2663  Protein of unknown function (DUF2663)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.1   0.00017      0.51      20     101 ..     264     350 ..     260     377 .. 0.79
   2 ?   -2.9   0.2       2.8   8.4e+03      23      41 ..     387     411 ..     380     440 .. 0.51

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00017
     DUF2663  20 lllsllallvlllfliyvlik.ssslssllsallessvlllllllvallyv....avkllkkKaeKaEkefhaLrceiiekSkdlwk 101
                 +++++ + + ++l+ i+ ++  s s     +++l+s+v+l ll++v + ++       + ++  eKa + f +Lr   i+   dl+ 
  EEA20656.1 264 MMWQMWTAFGIMLGNIMGVAFmSLSDDLSWRLMLGSTVVLPLLVCVQVYMCpespRWLIQHDQVEKAFRSFRKLRSHDIQAARDLYY 350
                 6788888888888888876555777777888899999999999999988873333456899***********************985 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 2.8
     DUF2663  23 sllallvlllfliyvlik......s 41 
                 s++ +++  +  + v+++      +
  EEA20656.1 387 SWIVMFMQQFCGVNVIAYysttifT 411
                 5555555555555555553222221 PP

>> DUF1700  Protein of unknown function (DUF1700)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.4      0.08   2.4e+02     116     151 ..     204     239 ..     175     240 .. 0.81
   2 ?    7.7   0.2   0.00079       2.4      74     117 ..     413     457 ..     400     492 .. 0.76

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.08
     DUF1700 116 allvsplvllvksllkgfeelslnvfvsigllglGl 151
                 ++ ++ ++  v s+ +g+ +  +n+f++  +lglG+
  EEA20656.1 204 TIFIACFFAAVCSIWEGVANTWVNLFIARFFLGLGI 239
                 457889999999*********************997 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.00079
     DUF1700  74 slknvskailavigLsllnlilvlipliviisl.vlsllvvalal 117
                 s  ++ +a+la++g ++ln ++ l++ ++i ++    ll++++ +
  EEA20656.1 413 SGYSIQSALLASMGTGILNWVFALPATFTIDTFgRRNLLLTTFPF 457
                 66799***********************99877523333333333 PP

>> DUF2427  Domain of unknown function (DUF2427)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0      0.47   1.4e+03      38      59 ..     112     133 ..     110     144 .. 0.77
   2 ?   -1.4   0.4      0.69   2.1e+03      50      96 ..     266     311 ..     258     314 .. 0.66
   3 ?    9.3   0.2   0.00031      0.93       2      60 ..     405     463 ..     403     492 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.47
     DUF2427  38 vLslaksrwylpvqivnlvlav 59 
                  L+   ++w+ p q   lv++ 
  EEA20656.1 112 LLREHTHKWHQPWQLYWLVIMC 133
                 6778889999999988887765 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.69
     DUF2427  50 vqivnlvlavlglllghiykgstPelypnniyaklswillillavqv 96 
                  q+     ++lg ++g+++++ + +l +  +    +++l +l++vqv
  EEA20656.1 266 WQMWTAFGIMLGNIMGVAFMSLSDDL-SWRLMLGSTVVLPLLVCVQV 311
                 56666666788888888888888777.44555555666666677776 PP

  == domain 3  score: 9.3 bits;  conditional E-value: 0.00031
     DUF2427   2 yntttyfttdephksalwvHiilmtlalvvvyPvalvLslaksrwylpvqivnlvlavl 60 
                 y+tt ++t+  +++sal++ + + +l +v+ +P+   +    +r  l++ + +l++++l
  EEA20656.1 405 YSTTIFTTSGYSIQSALLASMGTGILNWVFALPATFTIDTFGRRNLLLTTFPFLAICLL 463
                 566777788899************************99999999999998888887764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (629 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       745  (0.0415528); expected 358.6 (0.02)
Passed bias filter:                      429  (0.0239277); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.71u 0.31s 00:00:01.02 Elapsed: 00:00:00.47
# Mc/sec: 4008.08
//
Query:       EEA20657.1  [L=1721]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.8e-07   29.9  50.4     0.0012   19.3   3.9    9.7  9  NPV_P10          Nucleopolyhedrovirus P10 protein
    0.00037   18.2  34.3    0.00037   18.2  34.3    4.3  4  DUF3584          Protein of unknown function (DUF3584)
     0.0017   18.4  10.8     0.0017   18.4  10.8    7.3  7  DHR10            Designed helical repeat protein 10 domain
  ------ inclusion threshold ------
      0.013   15.5  53.2      0.067   13.2   8.1    7.7  7  DUF1664          Protein of unknown function (DUF1664)
       0.46    8.9   6.6        4.5    5.7   3.0    2.5  2  FUSC             Fusaric acid resistance protein family
        4.2    7.7  35.2       0.21   11.9   4.2    6.8  5  DUF948           Bacterial protein of unknown function (DUF94


Domain annotation for each model (and alignments):
>> NPV_P10  Nucleopolyhedrovirus P10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   1.7     0.012        36      15      65 ..     264     313 ..     260     320 .. 0.82
   2 !   14.8   2.7     1e-05      0.03       9      59 ..     318     369 ..     315     380 .. 0.91
   3 !    8.1   0.4    0.0012       3.7      10      55 ..     451     496 ..     445     498 .. 0.90
   4 !   19.3   3.9   3.9e-07    0.0012      10      60 ..     492     542 ..     488     546 .. 0.95
   5 ?    0.4   6.6       0.3   8.9e+02      11      62 ..     538     587 ..     536     638 .. 0.80
   6 ?    2.7   1.4     0.061   1.8e+02      10      53 ..     623     665 ..     616     711 .. 0.59
   7 ?   -0.9   0.0       0.8   2.4e+03      43      62 ..     770     789 ..     745     795 .. 0.62
   8 ?    4.1   0.0     0.022        66      37      67 ..     832     862 ..     812     870 .. 0.84
   9 ?   -3.9   0.0         6   1.8e+04      27      49 ..    1144    1166 ..    1136    1170 .. 0.73

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.012
     NPV_P10  15 avddkVdalqqqvddvqenlpdvtelnekLdaqsaqLaeletkvenIqdiL 65 
                 +v++k++ l+++++ +  n ++++el +  d+ +  + ++++kve+I+++ 
  EEA20657.1 264 KVQSKLKTLESKIQALIRNYEELNELVK-ADDTNSRILSMSAKVEHISKLV 313
                 6889999999999999999999999875.5777778889999999998765 PP

  == domain 2  score: 14.8 bits;  conditional E-value: 1e-05
     NPV_P10   9 IradikavddkVdalqq.qvddvqenlpdvtelnekLdaqsaqLaeletkve 59 
                 I++ i+avd+k++ l++ +++ ++e++++v++ n+k+  ++++ ++l++ v 
  EEA20657.1 318 IKDGIQAVDEKIEQLSNgKIEALEEKIEKVNNANDKIKTLNDKFEDLNKFVR 369
                 8999***********7539****************************99775 PP

  == domain 3  score: 8.1 bits;  conditional E-value: 0.0012
     NPV_P10  10 radikavddkVdalqqqvddvqenlpdvtelnekLdaqsaqLaele 55 
                 r d + ++ k+  +q+ +  +++  +dv+ lne L +++++L+ ++
  EEA20657.1 451 RGDFQTLEIKIGEMQKDILTLTARRNDVQSLNEPLKKMQEELQMIK 496
                 678899999**************************99999999876 PP

  == domain 4  score: 19.3 bits;  conditional E-value: 3.9e-07
     NPV_P10  10 radikavddkVdalqqqvddvqenlpdvtelnekLdaqsaqLaeletkven 60 
                 ++ ik+++ k++ +q+++  + +n  dv+ ++ekLd+++++++++ +kv++
  EEA20657.1 492 LQMIKDISRKLQEIQKNISALLDNGGDVQSMTEKLDKMTQKINNMLEKVQD 542
                 5789*****************************************999986 PP

  == domain 5  score: 0.4 bits;  conditional E-value: 0.3
     NPV_P10  11 adikavddkVdalqqqvddvqenlpdvtelnekLdaqsaqLaeletkvenIq 62 
                 + +++ ++k   +q++v++ ++    v+ l++ L+++ + L++ +t v+  +
  EEA20657.1 538 EKVQDSSQKTPNIQEEVQQKHA--SAVSRLEADLQDLEKRLTSQDTRVDVMN 587
                 6678888888888888886444..6677888888888888888888776544 PP

  == domain 6  score: 2.7 bits;  conditional E-value: 0.061
     NPV_P10  10 radikavddkVdalqqqvddvqenlpdvtelnekLdaqsaqLae 53 
                 r +i++v++   a++++v+++++   + +++n+  d+  +qL++
  EEA20657.1 623 RREISEVESNTGAIDDRVQHIANATVQ-SHINAYRDEVKDQLHD 665
                 667777777777777777555544444.4455555544444432 PP

  == domain 7  score: -0.9 bits;  conditional E-value: 0.8
     NPV_P10  43 kLdaqsaqLaeletkvenIq 62 
                 +L+++ + ++ +e +ve+ +
  EEA20657.1 770 RLEEIDERVKGIEHQVEKTK 789
                 44444444444444444444 PP

  == domain 8  score: 4.1 bits;  conditional E-value: 0.022
     NPV_P10  37 vtelnekLdaqsaqLaeletkvenIqdiLnp 67 
                 ++ l ++++++++ L++l+++v+  +diL++
  EEA20657.1 832 ISVLLDRVEGIQKRLKTLHKSVHGKTDILTE 862
                 6789999**********************93 PP

  == domain 9  score: -3.9 bits;  conditional E-value: 6
     NPV_P10   27 vddvqenlpdvtelnekLdaqsa 49  
                   dd+ e++ ++  l+ekLd+   
  EEA20657.1 1144 YDDLFEEFGEIPGLSEKLDEEER 1166
                  57778888888889999997665 PP

>> DUF3584  Protein of unknown function (DUF3584)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5  17.8     0.013        40     262     446 ..     206     387 ..     175     403 .. 0.66
   2 !   18.2  34.3   1.2e-07   0.00037     226     555 ..     363     693 ..     360     711 .. 0.67
   3 !    2.9  18.6     0.005        15     259     882 ..     571     790 ..     568     822 .. 0.47
   4 ?   -4.0  11.8      0.63   1.9e+03     349     499 ..    1127    1282 ..    1120    1326 .. 0.66

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.013
     DUF3584 262 lrLsllkgelkadeerlaekqeevqeakaelkqqlrtledelkeaidelnqelsaakaklaakesele.aleeqkkkyedadieklkadldqlpsirse 359
                 +++ +   +l + eer+ ++ +e + + +++   lrt  + +ke   + + e +a+++k++ k + le ++++  ++ye+  +++l +  d    i s 
  EEA20657.1 206 EEILSRMSNLSNIEERIGRRIQESNSELQRSSGDLRTRLEGFKELYTTDQHENNAKSDKVQSKLKTLEsKIQALIRNYEE--LNELVKADDTNSRILSM 302
                 44444556677888889999999999999999999999999999999999999999999999999998458888888876..44444444444444444 PP

     DUF3584 360 leeleeeldaltekhqdvqekydrrkqkikeeleeeleklkerleaireekdrlkaaieealealesqlrkqlea.qkeelneeekel 446
                  +++e+  ++++   +d++   ++   ki++  + ++e l+e+ e++ +++d+  ++ ++++e l++  r+++   +++++    ++l
  EEA20657.1 303 SAKVEHISKLVE--TNDIKDGIQAVDEKIEQLSNGKIEALEEKIEKVNNANDK-IKTLNDKFEDLNKFVRANNSDrKIQAFGASIEKL 387
                 444444444444..357777777777777777777777777777777777777.4566777777777777554330334444444444 PP

  == domain 2  score: 18.2 bits;  conditional E-value: 1.2e-07
     DUF3584 226 dveeWiediqalaaiekvrpeieklqeefeqlesl.elrLsllkgelkadeerlaekqeev...qeakaelkqqlrtledelkeaidelnqelsaakak 320
                 d +++++  ++ ++i++  ++iekl ++ ++  ++   + + l   + +  ++++e   e+   qe+ ++l  +++ le e++ ++++++++ ++++ k
  EEA20657.1 363 DLNKFVRANNSDRKIQAFGASIEKLSHQASKALTVdSPQFKALDNRVFEVLNEVSEAPMEFlglQESTQRLTLKIEILEREIQ-KVSNTRGDFQTLEIK 460
                 67788888999999**********99887766555156888888888888877777777763337888889999999999996.567889********* PP

     DUF3584 321 laakeselealeeqkkkye..dadieklkadldqlpsirseleeleeeldaltekhqdvqe...kydrrkqkikeeleeeleklkerleaireekdrlk 414
                 + ++++++  l +++++ +  ++ + k++++l ++  i+++l+e+++++ al+++  dvq+   k+d+  qki++ le+++   ++ + +i+ee ++++
  EEA20657.1 461 IGEMQKDILTLTARRNDVQslNEPLKKMQEELQMIKDISRKLQEIQKNISALLDNGGDVQSmteKLDKMTQKINNMLEKVQDSSQK-TPNIQEEVQQKH 558
                 ************9999876336889****************************998888751116666677777766665555444.577788887777 PP

     DUF3584 415 aaieealealesqlrkqleaqkeelneeekelesrlselklrldsatateEeleqieeadealekaqeelekaeaevealqaeeeqlrkkrdeadealq 513
                 a + + lea  + l+k+l  q +++   ++  +++l+  +  l+s  +  ++ e  +e+++ le  ++e+ + e +  a ++  +++ ++     +  +
  EEA20657.1 559 ASAVSRLEADLQDLEKRLTSQDTRVDVMNEAHQKKLNTHEESLNSLRIDLDKIE--TENKRSLEDLRREISEVESNTGAIDDRVQHIANA-----TVQS 650
                 777777777777777777777777666666666666666666666665555443..3444555555555555555555555544444332.....1222 PP

     DUF3584 514 kaerrleqlrqale.eleeqlsPqagsLlefLrkeapdWeesi 555
                 +++++  +++++l+ el++  +P   s le L ++  + ++ +
  EEA20657.1 651 HINAYRDEVKDQLHdELKQLDLPTWSSRLESLIDQVNGFKQAV 693
                 3344444444444313444444555555555555555555555 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.005
     DUF3584 259 slelrLsllkgelkadeerlaekqeevqeakaelkqqlrtledelkeaidelnqelsaakaklaakeseleal.....eeqkkkyedadieklkadldq 352
                  le+rL +    +    e+ ++k++  +e+ ++l+  l++ e e k + + l+ e+s+ + +  a+ +++ ++     ++  ++y d+  ++l+ +l q
  EEA20657.1 571 DLEKRLTSQDTRVDVMNEAHQKKLNTHEESLNSLRIDLDKIETENKRSLEDLRREISEVESNTGAIDDRVQHIanatvQSHINAYRDEVKDQLHDELKQ 669
                 444555554455555555555555555555666666666666666666666666666555555555555555422222334455666666666655555 PP

     DUF3584 353 l..psirseleeleeeldaltekhqd.vqekydrr..kqkikeelee..eleklker.leaireekdrlkaaieealealesqlrkqleaqkeelneee 443
                 l  p ++s le l  +++++ +++++ ++ ++ ++  k+ ike +    +l+++  + ++ i+e+ +++ +++e+++e                     
  EEA20657.1 670 LdlPTWSSRLESLIDQVNGFKQAVEQfIKDNLTEQlgKFDIKECKCSdvNLAGNTGDlEDSIKESMAEKCTDCEKKFET-------------------- 748
                 3224566666666666666655554323444333311222333222211344444444555555555555555555544.................... PP

     DUF3584 444 kelesrlselklrldsatateEeleqieeadealekaqeelekaeaevealqaeeeqlrkkrdeadealqkaerrleqlrqaleeleeqlsPqagsLle 542
                                                                                                                    
  EEA20657.1   - ---------------------------------------------------------------------------------------------------   -
                 ................................................................................................... PP

     DUF3584 543 fLrkeapdWeesigklispelLeRtDLdPelvessekdtlyGvsLdleridvpdyaaseeeLrerlqaleealqsaeakqkqaeeelkqlnaeleeakr 641
                                                                                                                    
  EEA20657.1   - ---------------------------------------------------------------------------------------------------   -
                 ................................................................................................... PP

     DUF3584 642 avaeaatalknardtlerlqnekesekdklekaiaerkqqaeeqlqkldaqlkqleeqqkaaleelkedlseerlekkakwqevvgeldeqlaelkkai 740
                                                                                                                    
  EEA20657.1   - ---------------------------------------------------------------------------------------------------   -
                 ................................................................................................... PP

     DUF3584 741 eaartqakarlkeleeaykreLkskdvDpetvkelkrkieeLekkieriekrreevreYraflqetwlkvdslaeerpalkeqveelesaaeeleqelt 839
                                                                                                                    
  EEA20657.1   - ---------------------------------------------------------------------------------------------------   -
                 ................................................................................................... PP

     DUF3584 840 rliedtklerkklekerkalekqldqldenlrklrdllsklae 882
                   ie ++++++ +e +r  + ++l+++de +++++  ++k  e
  EEA20657.1 749 -RIETVENNLEFFEGARANNGERLEEIDERVKGIEHQVEKTKE 790
                 .444444444444444444444444444444444444444333 PP

  == domain 4  score: -4.0 bits;  conditional E-value: 0.63
     DUF3584  349 dldqlpsirseleeleeeldaltekhqdv...qekydrrkqkikeeleeeleklkerleaireekdrl....kaaieealealesqlrkqleaqkee 438 
                  ++++ ++  +el++ ++++d l e+  ++    ek+d+++ kikee+ ++ e+ + ++e+ r+e++ l          ++ a+  +++ q e ++ +
  EEA20657.1 1127 EAEAQGKA-QELSNFHNNYDDLFEEFGEIpglSEKLDEEERKIKEEKRRKEEETRIEEEKRRDEEKILqrnvPLSLPGNVPAVDVPQNTQTETNQGA 1222
                  44444443.5788999999888877666433389***************999999998898888777633333345677889999999999988888 PP

     DUF3584  439 lneeekelesrlselklrldsatateEeleqieeadealekaqeelekaeaevealqaeee 499 
                   n + +  +++       ++++  + E+++  + ++e  +ka+e++ k +a+ ++ q+   
  EEA20657.1 1223 SNIQGEPPTQERRTIPEVQRNVASPVETSMSVKTSEE-QKKADETAGKKSASFSSSQQLSL 1282
                  8877776666666666666667777788887777665.47888888888888777665433 PP

>> DHR10  Designed helical repeat protein 10 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   2.5     0.053   1.6e+02      46     116 ..     202     273 ..     194     274 .. 0.85
   2 ?    1.7   1.7     0.085   2.5e+02      43      71 ..     338     366 ..     320     394 .. 0.70
   3 !   18.4  10.8   5.8e-07    0.0017       3     103 ..     446     546 ..     444     557 .. 0.92
   4 !    9.7  10.7   0.00029      0.85      36     116 ..     524     605 ..     516     606 .. 0.91
   5 ?    2.1   8.0     0.062   1.9e+02       4      82 ..     562     642 ..     559     651 .. 0.76
   6 ?   -3.1   0.6       2.6   7.7e+03      66      90 ..     764     788 ..     737     791 .. 0.52
   7 ?    0.9   5.9      0.15   4.4e+02      21      79 ..    1130    1188 ..    1125    1198 .. 0.51

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.053
       DHR10  46 eaelakleeakkklkelrdaleekeiel.relerkeerlqrqlenaeeklerlreqaeekreaakarleelr 116
                 +++l++  + +++l++ ++++  + +e+ +el+r    l+ +le  +e ++  +++ ++k ++ +++l+ l+
  EEA20657.1 202 STNLEEILSRMSNLSNIEERIGRRIQESnSELQRSSGDLRTRLEGFKELYTTDQHENNAKSDKVQSKLKTLE 273
                 5666677777888999999998886665169************************************99986 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.085
       DHR10  43 eeieaelakleeakkklkelrdaleekei 71 
                 e +e++++k++ a++k+k l+d+ e++++
  EEA20657.1 338 EALEEKIEKVNNANDKIKTLNDKFEDLNK 366
                 55677777777777777777777777665 PP

  == domain 3  score: 18.4 bits;  conditional E-value: 5.8e-07
       DHR10   3 slaeekeelaelErkarelqakidalqvvekdlrsciklleeieaelakleeakkklkelrdaleekeielrelerkeerlqrqlenaeeklerlreqa 101
                 ++++ +   + lE k+ e+q+ i +l+   +d++s+ + l++ ++el+  ++ ++kl+e +++++ +  +  ++++  e l +  ++ +  le+++ ++
  EEA20657.1 446 KVSNTRGDFQTLEIKIGEMQKDILTLTARRNDVQSLNEPLKKMQEELQMIKDISRKLQEIQKNISALLDNGGDVQSMTEKLDKMTQKINNMLEKVQDSS 544
                 57788888999**********************************************************999999999999999999999999999887 PP

       DHR10 102 ee 103
                 ++
  EEA20657.1 545 QK 546
                 65 PP

  == domain 4  score: 9.7 bits;  conditional E-value: 0.00029
       DHR10  36 rsciklleeieaelakleeakkklkelrdaleekei.elrelerkeerlqrqlenaeeklerlreqaeekreaakarleelr 116
                 +++ k+ ++i++ l+k++++++k  + ++++++k +  ++ le+  + l+++l +   + + + e +++k + ++++l +lr
  EEA20657.1 524 EKLDKMTQKINNMLEKVQDSSQKTPNIQEEVQQKHAsAVSRLEADLQDLEKRLTSQDTRVDVMNEAHQKKLNTHEESLNSLR 605
                 556678899************************98726899*************************************9997 PP

  == domain 5  score: 2.1 bits;  conditional E-value: 0.062
       DHR10   4 laeekeelaelErkarelqakidalqvvek.dlrsciklleeieaelakleea.kkklkelrdaleekeielrelerkeer 82 
                 +++  + l++lE++     +++d+++++ +  l+   + l+ +  +l k e++ k+ l++lr +++e e ++  ++ + ++
  EEA20657.1 562 VSRLEADLQDLEKRLTSQDTRVDVMNEAHQkKLNTHEESLNSLRIDLDKIETEnKRSLEDLRREISEVESNTGAIDDRVQH 642
                 566677899999999999999999998865156666778999999999988661567899999999988887777766665 PP

  == domain 6  score: -3.1 bits;  conditional E-value: 2.6
       DHR10  66 leekeielrelerkeerlqrqlena 90 
                  ++++++l+e++ + + ++ q+e+ 
  EEA20657.1 764 RANNGERLEEIDERVKGIEHQVEKT 788
                 3344444455555555555555544 PP

  == domain 7  score: 0.9 bits;  conditional E-value: 0.15
       DHR10   21 lqakidalqvvekdlrsciklleeieaelakleeakkklkelrdaleekeielrelerk 79  
                   q k+  l+++ +    +++   ei    +kl+e+++k+ke + + ee ++  +e  r 
  EEA20657.1 1130 AQGKAQELSNFHNNYDDLFEEFGEIPGLSEKLDEEERKIKEEKRRKEEETRIEEEKRRD 1188
                  45555555666666666666666666666666666666666555554443333333322 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   2.1    0.0015       4.6      38     112 ..     214     292 ..     205     305 .. 0.85
   2 ?    5.1   3.3    0.0075        22      45     112 ..     301     370 ..     296     383 .. 0.72
   3 ?   -0.3   0.1      0.35   1.1e+03      82     122 ..     402     442 ..     376     447 .. 0.80
   4 ?    2.2   6.3      0.06   1.8e+02      65     113 ..     478     526 ..     403     527 .. 0.69
   5 ?   13.2   8.1   2.2e-05     0.067      43     122 ..     495     574 ..     493     576 .. 0.88
   6 ?    3.0   1.7     0.032        96      57     109 ..     594     646 ..     579     660 .. 0.71
   7 ?    9.0   0.3   0.00047       1.4      52     109 ..     734     791 ..     716     801 .. 0.88

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0015
     DUF1664  38 slsdavesvskqleqvseslaatkrhLssridrvdk....kldeqkeiskeikeevtevredlseigedvesvkeaveg 112
                 +ls+  e++++++++  ++l++   +L  r++   +     + e+++ s ++++++++++++++++ ++ e+++e+v+ 
  EEA20657.1 214 NLSNIEERIGRRIQESNSELQRSSGDLRTRLEGFKElyttDQHENNAKSDKVQSKLKTLESKIQALIRNYEELNELVKA 292
                 899****************************9876422226788999999*************************9985 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0075
     DUF1664  45 svskqleqvseslaatkrhLssridrvdkkldeqk....eiskeikeevtevredlseigedvesvkeaveg 112
                 s+s ++e++s+ +++  +++++ i+ vd+k+++ +    e+ +e  e+v++++++++++++++e +++ v+ 
  EEA20657.1 301 SMSAKVEHISKLVET--NDIKDGIQAVDEKIEQLSngkiEALEEKIEKVNNANDKIKTLNDKFEDLNKFVRA 370
                 577777777776654..5788999999999998652111455666677888888999999999999998864 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.35
     DUF1664  82 skeikeevtevredlseigedvesvkeavegleskleriee 122
                  k++++ v ev +++se   ++  ++e  + l  k+e +e 
  EEA20657.1 402 FKALDNRVFEVLNEVSEAPMEFLGLQESTQRLTLKIEILER 442
                 57788999999999999999999999999999999998885 PP

  == domain 4  score: 2.2 bits;  conditional E-value: 0.06
     DUF1664  65 ssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeavegl 113
                  + +++  kk++e  +++k+i+++++e+++++s++ ++   v+++ e+l
  EEA20657.1 478 VQSLNEPLKKMQEELQMIKDISRKLQEIQKNISALLDNGGDVQSMTEKL 526
                 3334444456666666777777777777777777777666666666666 PP

  == domain 5  score: 13.2 bits;  conditional E-value: 2.2e-05
     DUF1664  43 vesvskqleqvseslaatkrhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvk.eavegleskleriee 122
                 ++++s++l++++++++a  ++   +++++ +kld++++ ++++ e+v++ ++++ +i+e+v++ + +av+ le+ l+++e+
  EEA20657.1 495 IKDISRKLQEIQKNISALLDN-GGDVQSMTEKLDKMTQKINNMLEKVQDSSQKTPNIQEEVQQKHaSAVSRLEADLQDLEK 574
                 567888888888888877665.789************************************9987358**********997 PP

  == domain 6  score: 3.0 bits;  conditional E-value: 0.032
     DUF1664  57 laatkrhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkea 109
                 l++  + L+s    +dk   e+k+  +++++e++ev++++ +i++ v+++ +a
  EEA20657.1 594 LNTHEESLNSLRIDLDKIETENKRSLEDLRREISEVESNTGAIDDRVQHIANA 646
                 55555555443334666666777788888888888888888888888888765 PP

  == domain 7  score: 9.0 bits;  conditional E-value: 0.00047
     DUF1664  52 qvseslaatkrhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkea 109
                 ++ e+ ++  ++++ ri++v+++l+  + + ++  e ++e+ e ++ i+++ve+ ke+
  EEA20657.1 734 SMAEKCTDCEKKFETRIETVENNLEFFEGARANNGERLEEIDERVKGIEHQVEKTKEI 791
                 45678889999*****************************************998876 PP

>> FUSC  Fusaric acid resistance protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.1     0.004        12     219     303 ..     203     300 ..     177     343 .. 0.75
   2 ?    5.7   3.0    0.0015       4.5     210     330 ..     491     628 ..     382     660 .. 0.62

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.004
        FUSC 219 ralrrllsrmlallallsslarllarlraeeaaavpelaallaelaal......eaaaaaealeaalaalrarlralrrale.......adadtaall 303
                   l ++lsrm +l+ +   + r+ ++ ++e +++  +l++ l+  ++l      e+ a +++ + +l++l+ +++al r+ e       ad   +++l
  EEA20657.1 203 TNLEEILSRMSNLSNIEERIGRRIQESNSELQRSSGDLRTRLEGFKELyttdqhENNAKSDKVQSKLKTLESKIQALIRNYEelnelvkADDTNSRIL 300
                 56778888888888888888899988888888888888888888888899998866667777777777777777777666665666665333333333 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.0015
        FUSC 210 esprirararalrrllsrmlallallsslarllarlraeeaaavpelaallaelaal....................eaaaaaealeaalaalrarlra 288
                 e + i + +r+l++++  + all     ++++ + l++                  +                     +++ +++++ a+ +l+a+l++
  EEA20657.1 491 ELQMIKDISRKLQEIQKNISALLDNGGDVQSMTEKLDK------------------MtqkinnmlekvqdssqktpnIQEEVQQKHASAVSRLEADLQD 571
                 22333333333333333333333333333333333333..................2223333333333336666664445555555555555555555 PP

        FUSC 289 lrrale..............adadtaalllarlaellael.aqllaslraleaaiaa 330
                 l+++l               ++ +t+++ l +l+ +l++  ++  +sl++l+++i++
  EEA20657.1 572 LEKRLTsqdtrvdvmneahqKKLNTHEESLNSLRIDLDKIeTENKRSLEDLRREISE 628
                 555555444444455555555555666666666655555523455555555555555 PP

>> DUF948  Bacterial protein of unknown function (DUF948)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   7.1      0.68     2e+03      25      72 ..     319     366 ..     247     389 .. 0.68
   2 ?    5.9   0.5    0.0051        15      32      88 ..     451     506 ..     437     514 .. 0.60
   3 ?   11.9   4.2     7e-05      0.21      21      80 ..     495     557 ..     494     578 .. 0.78
   4 ?    4.5   0.9     0.014        43      25      82 ..     591     648 ..     583     654 .. 0.86
   5 ?   -1.4   0.0      0.98   2.9e+03      35      70 ..     771     788 ..     764     793 .. 0.48

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.68
      DUF948  25 kktldeaaatieelekqvdpilkevedllakvnelledvneklekvdp 72 
                 k+ ++++ + ie+l +   + l+e  + ++++n+  + +n+k e++++
  EEA20657.1 319 KDGIQAVDEKIEQLSNGKIEALEEKIEKVNNANDKIKTLNDKFEDLNK 366
                 333444444444444444444444444445555555555555555555 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0051
      DUF948  32 aatieelekqvdpilkevedllakvnelledvneklekvdplteavadlgesvseln 88 
                 +   ++le +++++ k++ +l+a  n+ ++ +ne l+k+++  + ++d++++++e++
  EEA20657.1 451 RGDFQTLEIKIGEMQKDILTLTARRND-VQSLNEPLKKMQEELQMIKDISRKLQEIQ 506
                 444555666666666666666666666.55566655555555555555555555543 PP

  == domain 3  score: 11.9 bits;  conditional E-value: 7e-05
      DUF948  21 llklkktldeaaatieele...kqvdpilkevedllakvnelledvneklekvdplteavadl 80 
                 ++ +++ l+e+++ i  l     +v++++++++++++k+n++le v++ ++k  ++ e+v++ 
  EEA20657.1 495 IKDISRKLQEIQKNISALLdngGDVQSMTEKLDKMTQKINNMLEKVQDSSQKTPNIQEEVQQK 557
                 556667777777777776544478999999999999999999999999999999999988864 PP

  == domain 4  score: 4.5 bits;  conditional E-value: 0.014
      DUF948  25 kktldeaaatieelekqvdpilkevedllakvnelledvneklekvdplteavadlge 82 
                 +k l+  ++++++l+ ++d+i +e ++ l+  ++  ++v++ + ++d  ++++a+++ 
  EEA20657.1 591 QKKLNTHEESLNSLRIDLDKIETENKRSLEDLRREISEVESNTGAIDDRVQHIANATV 648
                 5677888999999999999999999999999999999999999999999999999875 PP

  == domain 5  score: -1.4 bits;  conditional E-value: 0.98
      DUF948  35 ieelekqvdpilkevedllakvnelledvneklekv 70 
                 +ee+ ++v++i ++ve+                   
  EEA20657.1 771 LEEIDERVKGIEHQVEK------------------T 788
                 33333444444333333..................2 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1721 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3315  (0.184896); expected 358.6 (0.02)
Passed bias filter:                      733  (0.0408835); expected 358.6 (0.02)
Passed Vit filter:                       137  (0.00764125); expected 17.9 (0.001)
Passed Fwd filter:                        73  (0.00407162); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 2.39u 0.43s 00:00:02.82 Elapsed: 00:00:00.63
# Mc/sec: 8198.30
//
Query:       EEA20658.1  [L=686]
Description: FAD monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.2e-88  297.7   0.0      2e-88  297.0   0.0    1.3  1  FAD_binding_3   FAD binding domain
    5.3e-58  195.7   0.0      1e-57  194.8   0.0    1.5  1  Phe_hydrox_dim  Phenol hydroxylase, C-terminal dimerisation d
    8.5e-05   21.9   0.0    0.00019   20.8   0.0    1.5  1  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    0.00072   18.9   0.0     0.0037   16.5   0.0    1.9  2  Thi4            Thi4 family
    0.00092   18.4   0.0     0.0017   17.6   0.0    1.4  1  FAD_binding_2   FAD binding domain
    0.00093   18.0   0.0     0.0014   17.5   0.0    1.2  1  HI0933_like     HI0933-like protein
     0.0041   16.2   0.1     0.0076   15.3   0.1    1.4  1  Lycopene_cycl   Lycopene cyclase protein
     0.0047   17.1   0.0      0.016   15.4   0.0    2.0  1  NAD_binding_8   NAD(P)-binding Rossmann-like domain
  ------ inclusion threshold ------
      0.014   16.0   0.0      0.035   14.7   0.0    1.7  1  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
      0.019   14.0   0.0        0.2   10.7   0.0    2.1  1  SE              Squalene epoxidase
       0.04   13.2   0.0      0.063   12.5   0.0    1.3  1  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
      0.047   13.3   0.0       0.11   12.1   0.0    1.8  2  DAO             FAD dependent oxidoreductase
      0.094   12.0   0.0       0.15   11.3   0.0    1.3  1  AlaDh_PNT_C     Alanine dehydrogenase/PNT, C-terminal domain
       0.15   11.1   0.1        0.3   10.1   0.1    1.4  1  GIDA            Glucose inhibited division protein A
       0.19   12.2   0.0       0.53   10.7   0.0    1.7  1  NAD_binding_7   Putative NAD(P)-binding


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  297.0   0.0   1.7e-91     2e-88       2     348 ..      12     424 ..      11     425 .. 0.88

  Alignments for each domain:
  == domain 1  score: 297.0 bits;  conditional E-value: 1.7e-91
                    EEEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSSS--EEEHHHHHHHHHTT-HHHHHHHSEECCCCEEEEEEE.................. CS
  FAD_binding_3   2 tdVlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlpradglnqrtmellrqlGledrilaegapnelmgealyne.................. 79 
                    tdVlIVGaGpaGlmla+ Ls+ Gv++++v+kr t++ +++adgl++rt+e++++   ++r+  e   n++ ++ ++n+                  
     EEA20658.1  12 TDVLIVGAGPAGLMLANWLSRCGVKTRIVDKRGTKIFNGQADGLQCRTLEIFDSFDFAHRAWCES--NHMLEICFWNPdesgtirrsgripdtipg 105
                    9************************************************************9999..***************************** PP

                    ........................CCCC........CEEEEEHH....CH.HCST-CEE--HHHHHHHHHHHHHHHTEEETCSEE........... CS
  FAD_binding_3  80 ........................lsdt........pkaradle....le.sspervtvypqteleriLvehaeerglqvrfkte........... 127
                                                                     +  ++ +  +yp t +++ L+e+ e+++ q +++++           
     EEA20658.1 106 isrfqqvvlhqgrierffldsikeH--SdikvergvL------PttfdFDvGKAGNFDDYPITVTLQTLSEN-EATPQQRNQHQKstdgnhttvsd 192
                    9999999999998777776664442..0334433221......13333444789999999999999999999.77774433333335599999999 PP

                    ..EECCEECCCC....CCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHHHTGGEEEEEEEEEEEEEEEEEEC-SCCCTTCCEEEEECCTTEEEEE CS
  FAD_binding_3 128 ..vesleqdeeg....vtaevrdketgeeetvrakYlvGaDGgrStvrktlgiefegeetvyeagvldvlfdadlsdiveplvlilsaesrgvmvi 217
                      ++s+++ +++     +a++ ++++  +etv+ak++vG+DG++S+vr++lg++++g +t+y +gvld+++ +d++di++  ++i+sa s++vm+i
     EEA20658.1 193 glFRSNLAPDDTddliNAANANKSNDHHIETVQAKFMVGCDGAHSWVRRQLGFSLQGDSTDYVWGVLDIIPITDFPDIRQR-CAIHSAISGSVMII 287
                    99777765433311213566667777777****************************************************.************** PP

                    ECCETEEEEEEEEECCE-GGGS....CCCHHHHHHHHHHHHHHTTSSCEE.EEEEEEEEEEEEEEESSSEET.TEEE-GGGTEEE-STTSHHHHHH CS
  FAD_binding_3 218 Plentlerfyvqvearaekeer....sekfteeevkarlreivgektldv.eieevsawtvaqrvaekyrkg.rvflaGDAaHihpPtgGqGlNta 307
                    P+en+l+r y+q++++++++++    +  +t++ + + +++i+++++ld    ++ +a++++qrv ++++   rvflaGDA+H+h+P++GqG+N++
     EEA20658.1 288 PRENKLVRLYIQLQTTEHVQNKgkvdRSGITPDIILQSAQKIMHPYKLDYsYCDWWTAYQIGQRVGDNFSLHeRVFLAGDAVHTHSPKAGQGMNVS 383
                    *******************99988888999********************889****************9776*********************** PP

                    HHHHHHHHHHHHHHHTTSS-GGGGHHHHHHHHHHHHHHHHH CS
  FAD_binding_3 308 iqDavnLawkLaavlkGeAkeelLdtYeeerravaqavvdf 348
                    +qD++nL+wkLa+v+kG  + ++L+tY++err++aq+++ f
     EEA20658.1 384 MQDTYNLGWKLAHVVKGYSDGSILKTYQSERRRIAQDLIAF 424
                    *************************************9987 PP

>> Phe_hydrox_dim  Phenol hydroxylase, C-terminal dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  194.8   0.0   8.5e-61     1e-57       1     166 []     461     647 ..     461     647 .. 0.98

  Alignments for each domain:
  == domain 1  score: 194.8 bits;  conditional E-value: 8.5e-61
  Phe_hydrox_dim   1 FtsGvgveYqpsllva....................evkskqnlatglrpGrrlpsakVvrvaDanpvdlqdeipsdGrfRilvfagdlsdaeqk 75 
                     F+sG++v+Y++s++va                    +  sk +latg+ +G+r+ps+kV++++Da+p++lq+ ++s+Gr+R++vf g+l+ + ++
      EEA20658.1 461 FASGIAVNYGASVIVAkegdaqeqgdgtdvignqllRSVSKPQLATGIDIGKRMPSFKVLNQSDARPWHLQELLKSNGRWRLIVFPGNLALPGNM 555
                     9***********************************8899******************************************************* PP

  Phe_hydrox_dim  76 srlsaladalsskesflsrftpadadvdsvievllihaaprkeieledlPevlrpfdeklgldyekvyvddesyhe.dgaaYekyGidkkrG 166
                     +r+++l+++l +++sf++++tp+++++ds+ievl+iha pr+++el dlPe+++p++ k g+dy+kv+vdd+syhe +g+aY +yGid++rG
      EEA20658.1 556 QRIQKLGERLGASDSFIRQYTPPGQPIDSLIEVLTIHAGPRTSFELLDLPEAFHPYNAKEGWDYWKVFVDDQSYHEgHGQAYVNYGIDPSRG 647
                     **********7778**************************************************************66**********9988 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8   0.0   1.6e-07   0.00019       2      38 ..      13      49 ..      12      53 .. 0.88

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 1.6e-07
                 SEEEE--SHHHHHHHHHHHHHTS-EEEEETTHCHHHC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  2 dvvviGgGpAGlaaaltlaqagakvtlvelegtclng 38
                 dv+++G+GpAGl +a  l++ g+k+ +v+++gt  ++
   EEA20658.1 13 DVLIVGAGPAGLMLANWLSRCGVKTRIVDKRGTKIFN 49
                 8***************************977776554 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   3.1e-06    0.0037      14      50 ..       8      43 ..       3      52 .. 0.90
   2 ?   -0.7   0.0      0.55   6.6e+02      64      91 ..     428     455 ..     425     471 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 3.1e-06
                HHTEEEEEEE--SHHHHHHHHHHHHCTTS-EEEEESS CS
        Thi4 14 kyaesDvvivGaGssGLtaayylakkpdlkvailers 50
                k  ++Dv+ivGaG++GL  a  l++  ++k+ i++++
  EEA20658.1  8 KTSQTDVLIVGAGPAGLMLANWLSRC-GVKTRIVDKR 43
                56789********************9.***9999875 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.55
                 BSEEEEETTTHHHHHHTT---EEESSEE CS
        Thi4  64 fsaivvrkpakelLdelgikyedegdyv 91 
                 fs++   +pak+++de g+ +e+ ++ +
  EEA20658.1 428 FSRLFSGRPAKDVMDEEGVSMEEFKTAF 455
                 88888899*************9988744 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   1.4e-06    0.0017       1      32 [.      13      44 ..      13      52 .. 0.93

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 1.4e-06
                   SEEEE--SHHHHHHHHHHHHTTT-EEEEESSS CS
  FAD_binding_2  1 DviViGsGlAGLaAAleaaeaGlkvavvekeq 32
                   Dv+++G+G AGL+ A  ++++G k+ +v+k +
     EEA20658.1 13 DVLIVGAGPAGLMLANWLSRCGVKTRIVDKRG 44
                   9****************************976 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   0.0   1.1e-06    0.0014       2      32 ..      13      43 ..      12      49 .. 0.91

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 1.1e-06
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SS CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVllleka 32
                 dv+++G+G+AGlm A  +++ g ++ +++k 
   EEA20658.1 13 DVLIVGAGPAGLMLANWLSRCGVKTRIVDKR 43
                 89***************************97 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.1   6.3e-06    0.0076       1      33 [.      13      43 ..      13      52 .. 0.85

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 6.3e-06
  Lycopene_cycl  1 DvvviGaGpAglslAarlteakpglkvvlieas 33
                   Dv+++GaGpAgl lA+ l  ++ g+k  +++  
     EEA20658.1 13 DVLIVGAGPAGLMLANWL--SRCGVKTRIVDKR 43
                   9*****************..9999999998865 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   1.4e-05     0.016       1      28 [.      16      43 ..      16      64 .. 0.92

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 1.4e-05
                   EE--SHHHHHHHHHHHCCTEEEEEE-SS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekr 28
                   IvGaG +Gl +A  L++ g++  +++kr
     EEA20658.1 16 IVGAGPAGLMLANWLSRCGVKTRIVDKR 43
                   9**************************8 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   0.0   2.9e-05     0.035       2      32 ..      14      44 ..      13      54 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 2.9e-05
                EEEECSSHHHHHHHHHHHHTTSEEEEEESSS CS
   Pyr_redox  2 vvvvGgGyiglElAgalaelgkkVtvversd 32
                v++vG+G  gl+lA+ l++ g k+ +v+ + 
  EEA20658.1 14 VLIVGAGPAGLMLANWLSRCGVKTRIVDKRG 44
                89*************************9875 PP

>> SE  Squalene epoxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00017       0.2       2     174 ..     226     405 ..     225     436 .. 0.61

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00017
          SE   2 AkltvvcDGifsklRkels.dnkvevtssfvGlv..lknaelpkknkghvilgk.pspvllYqisstetRilveikskklPsiangel.keylkeevaP 95 
                 Ak+ v cDG +s +R++l  + + + t++  G++  +  +++p+ ++   i +  +  v++ +   + +R+ +++++++  ++ +g++ ++ ++ ++  
  EEA20658.1 226 AKFMVGCDGAHSWVRRQLGfSLQGDSTDYVWGVLdiIPITDFPDIRQRCAIHSAiSGSVMIIPRENKLVRLYIQLQTTEHVQN-KGKVdRSGITPDIIL 323
                 66667777777777777766666677777777641133455555555555555545667777777777777777776655553.344413445555555 PP

          SE  96 qlPkelrksfkkaleeg..klrsmpnkflpasknekkGlillGDalnmRHPltggGmtvalnDivllskllkpl.edlsdee 174
                 q  +++ + +k   +           +++  + + ++ + l GDa+    P  g Gm v ++D + l   l  + + +sd +
  EEA20658.1 324 QSAQKIMHPYKLDYSYCdwWTAYQIGQRVGDNFSLHERVFLAGDAVHTHSPKAGQGMNVSMQDTYNLGWKLAHVvKGYSDGS 405
                 55555555554433332112222234555555666688999**********************9988766655536666654 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   5.3e-05     0.063       1      30 [.      15      43 ..      15      49 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 5.3e-05
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEkg 30
                 +I+GaGPaGl  a  l ++g+ +  i++k 
   EEA20658.1 15 LIVGAGPAGLMLANWLSRCGV-KTRIVDKR 43
                 6********************.57899985 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   9.1e-05      0.11       1      29 [.      13      43 ..      13     237 .. 0.86
   2 ?   -3.0   0.0       3.6   4.3e+03     217     258 ..     642     681 ..     635     684 .. 0.64

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 9.1e-05
                EEEEECTSHHHHHHHHHHHHTT..EEEEESS CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..Vtllekg 29
                dv+i+G+G +Gl  A +L+r g  + +++k+
  EEA20658.1 13 DVLIVGAGPAGLMLANWLSRCGvkTRIVDKR 43
                8*****************9999999999998 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 3.6
                 EEEEEEEEEEEEECCTHSTGSGCSEEEEEEEETTTTEEEEEE CS
         DAO 217 ispvrgqvlvlkplseklvspaailpvpetdddgrgvyvtpr 258
                 i p rg ++ ++p +   ++  a +  ++    +++ +++p 
  EEA20658.1 642 IDPSRGASVIVRPDQY-VSWVGAMDD-YDEMAKFFSGFMRPQ 681
                 6788999999977655.323323333.337777777788775 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00013      0.15      23      64 ..       7      47 ..       1      79 [. 0.83

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00013
                 ETCB---EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHHHH CS
  AlaDh_PNT_C 23 vpgvepakvlviGgGvaGlqAiatakglgakVtvlDvrparl 64
                 ++ +++  vl++G+G aGl  ++  ++ g k++++D+r +++
   EEA20658.1  7 IK-TSQTDVLIVGAGPAGLMLANWLSRCGVKTRIVDKRGTKI 47
                 55.67899*****************************98765 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.1   0.00025       0.3       1      35 [.      13      47 ..      13      54 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00025
                CEEEE-SSHHHHHHHHHHHHTT--EEEEES-GGGT CS
        GIDA  1 dviViGgGhAGceAAlaaarlGakvlLithkldti 35
                dv ++G+G AG+  A  ++r G+k+ ++ ++  +i
  EEA20658.1 13 DVLIVGAGPAGLMLANWLSRCGVKTRIVDKRGTKI 47
                799***********************997766665 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00045      0.53       4      71 ..       8      86 ..       7      99 .. 0.65

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00045
  NAD_binding_7  4 dlkgkkvlvvGgGevAarkvrklleagakvtvvapevkeeleelvk.laeee........l..ekdlegadlviaatdd 71
                   + ++  vl+vG+G+ ++  ++ l ++g k  +v+++ +++ +++ + l+ ++        +  ++++e  +++ ++  +
     EEA20658.1  8 KTSQTDVLIVGAGPAGLMLANWLSRCGVKTRIVDKRGTKIFNGQADgLQCRTleifdsfdFahRAWCESNHMLEICFWN 86
                   567889*****************************97666663333222222111111112334556666665555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (686 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       355  (0.0198003); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.46
# Mc/sec: 4504.28
//
Query:       EEA20659.1  [L=506]
Description: FAD monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.9e-89  299.0   0.0    7.8e-89  298.3   0.0    1.3  1  FAD_binding_3  FAD binding domain
    5.7e-05   22.5   0.0    0.00013   21.3   0.0    1.5  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    0.00053   19.3   0.0     0.0025   17.1   0.0    1.8  2  Thi4           Thi4 family
    0.00063   18.5   0.0    0.00095   18.0   0.0    1.2  1  HI0933_like    HI0933-like protein
    0.00066   18.9   0.0     0.0012   18.1   0.0    1.3  1  FAD_binding_2  FAD binding domain
     0.0029   16.7   0.1     0.0051   15.9   0.1    1.4  1  Lycopene_cycl  Lycopene cyclase protein
     0.0042   17.3   0.0      0.011   15.9   0.0    1.7  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
     0.0083   15.2   0.0       0.45    9.5   0.0    2.1  2  SE             Squalene epoxidase
     0.0099   16.4   0.0      0.024   15.2   0.0    1.6  1  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
      0.029   13.6   0.0      0.044   13.0   0.0    1.3  1  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
      0.046   13.3   0.1      0.074   12.6   0.1    1.5  1  DAO            FAD dependent oxidoreductase
      0.065   12.5   0.0      0.099   11.9   0.0    1.3  1  AlaDh_PNT_C    Alanine dehydrogenase/PNT, C-terminal domain
       0.11   12.9   0.0       0.34   11.4   0.0    1.7  2  NAD_binding_7  Putative NAD(P)-binding
       0.12   11.7   0.1       0.22   10.8   0.1    1.4  1  FAD_oxidored   FAD dependent oxidoreductase
       0.13   11.3   0.1       0.21   10.7   0.1    1.2  1  GIDA           Glucose inhibited division protein A


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  298.3   0.0   6.5e-92   7.8e-89       2     348 ..      12     424 ..      11     425 .. 0.88

  Alignments for each domain:
  == domain 1  score: 298.3 bits;  conditional E-value: 6.5e-92
                    EEEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSSS--EEEHHHHHHHHHTT-HHHHHHHSEECCCCEEEEEEE.................. CS
  FAD_binding_3   2 tdVlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlpradglnqrtmellrqlGledrilaegapnelmgealyne.................. 79 
                    tdVlIVGaGpaGlmla+ Ls+ Gv++++v+kr t++ +++adgl++rt+e++++   ++r+  e   n++ ++ ++n+                  
     EEA20659.1  12 TDVLIVGAGPAGLMLANWLSRCGVKTRIVDKRGTKIFNGQADGLQCRTLEIFDSFDFAHRAWCES--NHMLEICFWNPdesgtirrsgripdtipg 105
                    9************************************************************9999..***************************** PP

                    ........................CCCC........CEEEEEHH....CH.HCST-CEE--HHHHHHHHHHHHHHHTEEETCSEE........... CS
  FAD_binding_3  80 ........................lsdt........pkaradle....le.sspervtvypqteleriLvehaeerglqvrfkte........... 127
                                                                     +  ++ +  +yp t +++ L+e+ e+++ q +++++           
     EEA20659.1 106 isrfqqvvlhqgrierffldsikeH--SdikvergvL------PttfdFDvGKAGNFDDYPITVTLQTLSEN-EATPQQRNQHQKstdgnhttvsd 192
                    9999999999998777776664442..0334433221......13333444789999999999999999999.77774433333335599999999 PP

                    ..EECCEECCCC....CCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHHHTGGEEEEEEEEEEEEEEEEEEC-SCCCTTCCEEEEECCTTEEEEE CS
  FAD_binding_3 128 ..vesleqdeeg....vtaevrdketgeeetvrakYlvGaDGgrStvrktlgiefegeetvyeagvldvlfdadlsdiveplvlilsaesrgvmvi 217
                      ++s+++ +++     +a++ ++++  +etv+ak++vG+DG++S+vr++lg++++g +t+y +gvld+++ +d++di++  ++i+sa s++vm+i
     EEA20659.1 193 glFRSNLAPDDTddliNAANANKSNDHHIETVQAKFMVGCDGAHSWVRRQLGFSLQGDSTDYVWGVLDIIPITDFPDIRQR-CAIHSAISGSVMII 287
                    99777765433311213566667777777****************************************************.************** PP

                    ECCETEEEEEEEEECCE-GGGS....CCCHHHHHHHHHHHHHHTTSSCEE.EEEEEEEEEEEEEEESSSEET.TEEE-GGGTEEE-STTSHHHHHH CS
  FAD_binding_3 218 Plentlerfyvqvearaekeer....sekfteeevkarlreivgektldv.eieevsawtvaqrvaekyrkg.rvflaGDAaHihpPtgGqGlNta 307
                    P+en+l+r y+q++++++++++    +  +t++ + + +++i+++++ld    ++ +a++++qrv ++++   rvflaGDA+H+h+P++GqG+N++
     EEA20659.1 288 PRENKLVRLYIQLQTTEHVQNKgkvdRSGITPDIILQSAQKIMHPYKLDYsYCDWWTAYQIGQRVGDNFSLHeRVFLAGDAVHTHSPKAGQGMNVS 383
                    *******************99988888999********************889****************9776*********************** PP

                    HHHHHHHHHHHHHHHTTSS-GGGGHHHHHHHHHHHHHHHHH CS
  FAD_binding_3 308 iqDavnLawkLaavlkGeAkeelLdtYeeerravaqavvdf 348
                    +qD++nL+wkLa+v+kG  + ++L+tY++err++aq+++ f
     EEA20659.1 384 MQDTYNLGWKLAHVVKGYSDGSILKTYQSERRRIAQDLIAF 424
                    *************************************9987 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.0   1.1e-07   0.00013       2      38 ..      13      49 ..      12      53 .. 0.88
   2 ?   -3.7   0.0       4.7   5.6e+03     268     278 ..     359     369 ..     355     380 .. 0.74

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 1.1e-07
                 SEEEE--SHHHHHHHHHHHHHTS-EEEEETTHCHHHC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  2 dvvviGgGpAGlaaaltlaqagakvtlvelegtclng 38
                 dv+++G+GpAGl +a  l++ g+k+ +v+++gt  ++
   EEA20659.1 13 DVLIVGAGPAGLMLANWLSRCGVKTRIVDKRGTKIFN 49
                 8***************************977776554 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 4.7
                  STTEEE-GGGC CS
                  xxxxxxxxxxx RF
  Pyr_redox_2 268 vpgiyaiGDva 278
                  ++ ++++GD +
   EEA20659.1 359 HERVFLAGDAV 369
                  5789*****88 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   0.0   2.1e-06    0.0025      14      50 ..       8      43 ..       3      52 .. 0.90
   2 ?   -0.8   0.0       0.6   7.1e+02      64      90 ..     428     454 ..     425     465 .. 0.84

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 2.1e-06
                HHTEEEEEEE--SHHHHHHHHHHHHCTTS-EEEEESS CS
        Thi4 14 kyaesDvvivGaGssGLtaayylakkpdlkvailers 50
                k  ++Dv+ivGaG++GL  a  l++  ++k+ i++++
  EEA20659.1  8 KTSQTDVLIVGAGPAGLMLANWLSRC-GVKTRIVDKR 43
                56789********************9.***9999875 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.6
                 BSEEEEETTTHHHHHHTT---EEESSE CS
        Thi4  64 fsaivvrkpakelLdelgikyedegdy 90 
                 fs++   +pak+++de g+ +e+ ++ 
  EEA20659.1 428 FSRLFSGRPAKDVMDEEGVSMEEFKTA 454
                 88888899************9997764 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   7.9e-07   0.00095       2      32 ..      13      43 ..      12      49 .. 0.91

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 7.9e-07
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SS CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVllleka 32
                 dv+++G+G+AGlm A  +++ g ++ +++k 
   EEA20659.1 13 DVLIVGAGPAGLMLANWLSRCGVKTRIVDKR 43
                 89***************************97 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   9.7e-07    0.0012       1      32 [.      13      44 ..      13      52 .. 0.93

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 9.7e-07
                   SEEEE--SHHHHHHHHHHHHTTT-EEEEESSS CS
  FAD_binding_2  1 DviViGsGlAGLaAAleaaeaGlkvavvekeq 32
                   Dv+++G+G AGL+ A  ++++G k+ +v+k +
     EEA20659.1 13 DVLIVGAGPAGLMLANWLSRCGVKTRIVDKRG 44
                   9****************************976 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.1   4.3e-06    0.0051       1      33 [.      13      43 ..      13      53 .. 0.85

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 4.3e-06
  Lycopene_cycl  1 DvvviGaGpAglslAarlteakpglkvvlieas 33
                   Dv+++GaGpAgl lA+ l  ++ g+k  +++  
     EEA20659.1 13 DVLIVGAGPAGLMLANWL--SRCGVKTRIVDKR 43
                   9*****************..9999999998865 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   9.3e-06     0.011       1      28 [.      16      43 ..      16      65 .. 0.92

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 9.3e-06
                   EE--SHHHHHHHHHHHCCTEEEEEE-SS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekr 28
                   IvGaG +Gl +A  L++ g++  +++kr
     EEA20659.1 16 IVGAGPAGLMLANWLSRCGVKTRIVDKR 43
                   9**************************8 PP

>> SE  Squalene epoxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0      0.02        24       2      20 ..     226     244 ..     225     334 .. 0.87
   2 !    9.5   0.0   0.00038      0.45     131     184 ..     361     411 ..     342     463 .. 0.81

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.02
          SE   2 AkltvvcDGifsklRkels 20 
                 Ak+ v cDG +s +R++l 
  EEA20659.1 226 AKFMVGCDGAHSWVRRQLG 244
                 88999***********996 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00038
          SE 131 GlillGDalnmRHPltggGmtvalnDivllskllkpl.edlsdeekvleelksfy 184
                  + l GDa+    P  g Gm v ++D + l   l  + + +sd +     lk++ 
  EEA20659.1 361 RVFLAGDAVHTHSPKAGQGMNVSMQDTYNLGWKLAHVvKGYSDGSI----LKTYQ 411
                 57899*********************99887666555366666543....34444 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0     2e-05     0.024       2      32 ..      14      44 ..      13      54 .. 0.90

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 2e-05
                EEEECSSHHHHHHHHHHHHTTSEEEEEESSS CS
   Pyr_redox  2 vvvvGgGyiglElAgalaelgkkVtvversd 32
                v++vG+G  gl+lA+ l++ g k+ +v+ + 
  EEA20659.1 14 VLIVGAGPAGLMLANWLSRCGVKTRIVDKRG 44
                89*************************9875 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   3.7e-05     0.044       1      30 [.      15      43 ..      15      49 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 3.7e-05
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEkg 30
                 +I+GaGPaGl  a  l ++g+ +  i++k 
   EEA20659.1 15 LIVGAGPAGLMLANWLSRCGV-KTRIVDKR 43
                 6********************.57899985 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.1   6.2e-05     0.074       1      29 [.      13      43 ..      13     226 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 6.2e-05
                EEEEECTSHHHHHHHHHHHHTT..EEEEESS CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..Vtllekg 29
                dv+i+G+G +Gl  A +L+r g  + +++k+
  EEA20659.1 13 DVLIVGAGPAGLMLANWLSRCGvkTRIVDKR 43
                8*****************9999999999998 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   8.3e-05     0.099      23      64 ..       7      47 ..       1      80 [. 0.83

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 8.3e-05
                 ETCB---EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHHHH CS
  AlaDh_PNT_C 23 vpgvepakvlviGgGvaGlqAiatakglgakVtvlDvrparl 64
                 ++ +++  vl++G+G aGl  ++  ++ g k++++D+r +++
   EEA20659.1  7 IK-TSQTDVLIVGAGPAGLMLANWLSRCGVKTRIVDKRGTKI 47
                 55.67899*****************************98765 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00028      0.34       4      72 ..       8      87 ..       7     100 .. 0.65
   2 ?   -2.5   0.0       5.8   6.9e+03      61      78 ..     203     221 ..     152     230 .. 0.58

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00028
  NAD_binding_7  4 dlkgkkvlvvGgGevAarkvrklleagakvtvvapevkeeleelvk.laeee........l..ekdlegadlviaatddr 72
                   + ++  vl+vG+G+ ++  ++ l ++g k  +v+++ +++ +++ + l+ ++        +  ++++e  +++ ++  ++
     EEA20659.1  8 KTSQTDVLIVGAGPAGLMLANWLSRCGVKTRIVDKRGTKIFNGQADgLQCRTleifdsfdFahRAWCESNHMLEICFWNP 87
                   567889*****************************976666633332222221111111124356666666665555555 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 5.8
  NAD_binding_7  61 gad.lviaatddrelneri 78 
                    ++d l+ aa  +++  ++i
     EEA20659.1 203 DTDdLINAANANKSNDHHI 221
                    2332555555555555555 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.1   0.00018      0.22       1      32 [.      13      44 ..      13      45 .. 0.96

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00018
  FAD_oxidored  1 DvvVvGGgpaGvaAAiaAaraGakvlLveerg 32
                  Dv++vG+gpaG++ A    r G k+ +v++rg
    EEA20659.1 13 DVLIVGAGPAGLMLANWLSRCGVKTRIVDKRG 44
                  9****************************986 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.1   0.00017      0.21       1      35 [.      13      47 ..      13      54 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00017
                CEEEE-SSHHHHHHHHHHHHTT--EEEEES-GGGT CS
        GIDA  1 dviViGgGhAGceAAlaaarlGakvlLithkldti 35
                dv ++G+G AG+  A  ++r G+k+ ++ ++  +i
  EEA20659.1 13 DVLIVGAGPAGLMLANWLSRCGVKTRIVDKRGTKI 47
                799***********************997766665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (506 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       570  (0.0317921); expected 358.6 (0.02)
Passed bias filter:                      509  (0.0283898); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.63u 0.31s 00:00:00.94 Elapsed: 00:00:00.49
# Mc/sec: 3133.86
//
Query:       EEA20660.1  [L=358]
Description: SNARE complex subunit (Vam7), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.7e-16   57.9   0.2    2.9e-15   56.2   0.1    1.8  2  PX        PX domain


Domain annotation for each model (and alignments):
>> PX  PX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.2   0.1   1.6e-19   2.9e-15      19     111 ..      16     109 ..       4     111 .. 0.83
   2 ?   -1.0   0.0     0.096   1.7e+03      46      56 ..     238     248 ..     170     318 .. 0.69

  Alignments for each domain:
  == domain 1  score: 56.2 bits;  conditional E-value: 1.6e-19
                 EEEEEEEEEETTSSSEEEEEEEHHHHHHHHHHHHHHHTTSTSTSSSTSGSSSSSCTTSHHHHHHHHHHHHHHHHHHHT..SCHHHHSHHHHHHHH CS
          PX  19 hsyylyevelktgakewtvkRrYsdFeeLhskLlrkfprvkiPplPkkvlfgsvrkkdeefiekrrkgLeeyLqrlln..hpelrnsevlteFLe 111
                 + y++y+++++   ++  v++rYs+F  +h++L ++       plPkk+++ + ++++e+  e+rr+gLe+yLq + n  ++ +rn++v ++FL+
  EEA20660.1  16 GDYTTYNITVRLPLRSLVVQKRYSEFSTFHDDLVNQVGIQPPVPLPKKSWIHN-TNSNEKLREERRQGLEKYLQAINNaeDQRWRNTSVWRSFLN 109
                 457777777777778***********************7777799****9998.9*******************996511556777*******96 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.096
                 HHHHHHHHHHT CS
          PX  46 eLhskLlrkfp 56 
                 +Lh+ +l+k +
  EEA20660.1 238 NLHNAMLQKSK 248
                 44444444433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (358 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       937  (0.0522617); expected 358.6 (0.02)
Passed bias filter:                      395  (0.0220313); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.24s 00:00:00.73 Elapsed: 00:00:00.41
# Mc/sec: 2618.56
//
Query:       EEA20661.1  [L=668]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      0.001   18.8   0.2     0.0042   16.8   0.0    2.1  2  PGAP1          PGAP1-like protein
     0.0026   18.4   0.1     0.0052   17.4   0.0    1.7  2  Abhydrolase_6  Alpha/beta hydrolase family
  ------ inclusion threshold ------
       0.01   15.8   1.0      0.027   14.4   0.0    2.0  2  UPF0227        Uncharacterised protein family (UPF0227)
      0.037   13.9   0.0       0.13   12.1   0.0    1.9  2  Abhydrolase_3  alpha/beta hydrolase fold
      0.039   13.8   0.0      0.079   12.8   0.0    1.4  1  Lipase_3       Lipase (class 3)
       0.04   13.2   0.0      0.069   12.4   0.0    1.3  1  Hydrolase_4    Serine aminopeptidase, S33
      0.051   13.7   0.0       0.11   12.6   0.0    1.5  1  Thioesterase   Thioesterase domain
        0.1   12.1   0.2       0.28   10.6   0.0    1.7  2  DUF676         Putative serine esterase (DUF676)


Domain annotation for each model (and alignments):
>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.0   1.9e-06    0.0042      86     110 ..     139     163 ..      77     183 .. 0.88
   2 ?   -1.6   0.0      0.81   1.8e+03     114     186 ..     376     451 ..     371     459 .. 0.66

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 1.9e-06
       PGAP1  86 sekeptsviliGHSmGGivaraalt 110
                 +e ++t+vil+GHS+GGi+a  ++ 
  EEA20661.1 139 HESDQTDVILLGHSLGGILAAEVAL 163
                 67899**************965544 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.81
       PGAP1 114 yikqsvntiltlasPhalpplsfdkdilklyervnefwkkeleekek.lenvl..lvsitggird.smvpaeyssle 186
                 ++ +s++++  l sP+ ++   +d++  ++ ++v+  + +e  ++++ ++ v+  +v i + + d   v+++y+ l 
  EEA20661.1 376 IATDSIENLTKLPSPVLSAES-IDNSSDDYLTEVEPSPMEESPSQRQsFDAVSelSVDIEDNKIDkDKVENDYTALL 451
                 677899999999999988876.8999999999999888777655544544444114444444443145666666665 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.0   2.3e-06    0.0052      62      96 ..     134     193 ..      77     343 .. 0.64
   2 ?   -3.6   0.1       6.2   1.4e+04      96     117 ..     599     624 ..     573     664 .. 0.45

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 2.3e-06
                    .........TTSEEEEEETCHHHHHHHHHHCC.............EEEEES-........... CS
  Abhydrolase_6  62 a.......gggpvvlvGHSlGGalalaaapla...........lvvgvlldp..........p 96 
                    +       +  +v+l+GHSlGG+la++   +a           +++  +l +           
     EEA20661.1 134 EwliphesDQTDVILLGHSLGGILAAE---VAltetddannstRHRHRMLGTinfdvpflgmH 193
                    2444455577899**************...776667777777543335555544443333331 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 6.2
                    ......----TTTS----TTHHHHHH CS
  Abhydrolase_6  96 pp....talpagllaaalelllalla 117
                    pp     ++++++++ +++ +++++a
     EEA20661.1 599 PPhttkNSTDPLWVRIFMPDIDQVIA 624
                    33333223333333333333333333 PP

>> UPF0227  Uncharacterised protein family (UPF0227)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   1.2e-05     0.027       2      77 ..      77     162 ..      76     165 .. 0.65
   2 ?   -1.3   0.3      0.78   1.7e+03      15      56 ..     473     513 ..     468     518 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.2e-05
     UPF0227   2 llYlHGFdSSPls......hkaqllsqfiaedvlaielsvl..klkedpqqalkeleklvaelgddn..illvGssLGGyyatrlg 77 
                 l+Y+HGF     s      h  +l+s+ +a+ ++  + + +  k +  +  a  e  + +  + +d+  ++l G sLGG +a+ ++
  EEA20661.1  77 LIYIHGFMGAEDSfrefpaHVHNLISNTLADSHVIYSKIYPryKSRRAMTAARDEFSEWLIPHESDQtdVILLGHSLGGILAAEVA 162
                 8******8755551111113457889999888877665554015555666666677666555555555899**********98765 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.78
     UPF0227  15 hkaqllsqfiaedvlaielsvlklkedpqqalkeleklvael 56 
                 +++  l+q+ +e+ ++++l  + lke+   ++ke ekl ++l
  EEA20661.1 473 ANKDILKQAQKEHARQVKLHGRSLKEHN-TTIKEREKLAQKL 513
                 4677889999999999999999999875.5788888777665 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   5.6e-05      0.13      57      97 ..     134     170 ..      95     258 .. 0.85
   2 ?   -2.0   0.0       1.2   2.8e+03     175     197 ..     498     520 ..     471     526 .. 0.62

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 5.6e-05
                    HHHHHTHHHHTETTCEEEEEEETHHHHHHHHHHHHHHHTT- CS
  Abhydrolase_3  57 rwlaeqawelgadpsrivlaGdSaGGnlaaavalrardege 97 
                    +wl  +    + d++ ++l+G S GG laa val   d+ +
     EEA20661.1 134 EWLIPH----ESDQTDVILLGHSLGGILAAEVALTETDDAN 170
                    455555....57999******************98877643 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.2
                    TT-TTHHHHHHHHHHHHHTT--E CS
  Abhydrolase_3 175 efDplrdegeayaerlraagvev 197
                    e+ +  +e e++a++l ++g+++
     EEA20661.1 498 EHNTTIKEREKLAQKLSKKGKKS 520
                    44555556666666666666665 PP

>> Lipase_3  Lipase (class 3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   3.5e-05     0.079      32      83 ..     108     162 ..      78     191 .. 0.63

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 3.5e-05
                 T-EEEHHHHHHHH.S-HHHHHHHHHHHHHHHTT..-EEEEEEEETHHHHHHHHHH CS
    Lipase_3  32 ggkvhsgfleaye.eslreqvlkelkrllekyp..eysivvtGHSLGgalAlLaa 83 
                 +  + s ++  y+ + + ++ ++e++++l  ++  ++ +++ GHSLGg lA+ +a
  EEA20661.1 108 SHVIYSKIYPRYKsRRAMTAARDEFSEWLIPHEsdQTDVILLGHSLGGILAAEVA 162
                 3333333344444677888889999996655554469***********9996444 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   3.1e-05     0.069      71      99 ..     139     167 ..     123     173 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 3.1e-05
  Hydrolase_4  71 eehpelplfllGhSmGGliallyllrypd 99 
                   e+ ++ ++llGhS+GG++a++++l++ d
   EEA20661.1 139 HESDQTDVILLGHSLGGILAAEVALTETD 167
                  4556679****************977665 PP

>> Thioesterase  Thioesterase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   4.8e-05      0.11      53      84 ..     130     162 ..      77     165 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 4.8e-05
                   HHHHHHHHHH-SSS.SEEEEEETHHHHHHHHHH CS
  Thioesterase  53 aeyaealrqiqpeg.PyalfGhSlGgllAfevA 84 
                   +e+ e l ++  +   + l GhSlGg+lA evA
    EEA20661.1 130 DEFSEWLIPHESDQtDVILLGHSLGGILAAEVA 162
                   566677777777777999**************9 PP

>> DUF676  Putative serine esterase (DUF676)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00013      0.28       7     130 ..      76     193 ..      72     240 .. 0.77
   2 ?   -2.5   0.3       1.4     3e+03     150     184 ..     483     518 ..     475     527 .. 0.68

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00013
      DUF676   7 LvVlvHGlqgnsaDlelikeqlekikeklpeekieflmsennesktfkgidvlgerlaeevlevvkkkkdknkkiSfvghSlGglia.raaiaklkeke 104
                 L++ +HG+ g ++ ++   ++++++ ++   +  ++ ++   + k+   ++  ++   e+++ +  ++ d +    ++ghSlGg+ a  +a++   +++
  EEA20661.1  76 LLIYIHGFMGAEDSFREFPAHVHNLISNTLADSHVIYSKIYPRYKSRRAMTAARDEFSEWLIPHESDQTDVI----LLGHSLGGILAaEVALTETDDAN 170
                 789999999999999999888888866666666666677777888888899999999999988877777774....9*******875157777777666 PP

      DUF676 105 mtlkeaikglepvtfitlasPhLGvl 130
                 +  +   +  ++   i +  P+LG+ 
  EEA20661.1 171 NSTR---HRHRMLGTINFDVPFLGMH 193
                 6323...3446666777788999874 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 1.4
      DUF676 150 slsmeqlgltGrdLflkddk.deknsllykllkdek 184
                 +  ++q++l Gr L   +++ +e+++l  kl+k+ k
  EEA20661.1 483 KEHARQVKLHGRSLKEHNTTiKEREKLAQKLSKKGK 518
                 367889999999998877652556667777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (668 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1237  (0.0689944); expected 358.6 (0.02)
Passed bias filter:                      636  (0.0354733); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.74u 0.32s 00:00:01.06 Elapsed: 00:00:00.48
# Mc/sec: 4204.36
//
Query:       EEA20662.1  [L=480]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.9e-11   43.1   0.0    2.7e-08   33.8   0.0    3.1  2  SIP1      Survival motor neuron (SMN) interacting protein 1 (


Domain annotation for each model (and alignments):
>> SIP1  Survival motor neuron (SMN) interacting protein 1 (SIP1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.8   0.0   1.5e-12   2.7e-08       8     194 ..     110     338 ..     103     354 .. 0.59
   2 !    5.5   0.0   0.00066        12     200     219 .]     451     470 ..     434     470 .. 0.82

  Alignments for each domain:
  == domain 1  score: 33.8 bits;  conditional E-value: 1.5e-12
        SIP1   8 ddesgpPedgeeYLrrVryEakrcpdVvva.kidpsklakkq.....................tvympsipeiakcpesllP...........tkeWeq 73 
                   + gpPedg+eYLr Vr Ea+++p+  va k ++++ + kq                     t y+  ++ + ++++s  P           ++++ +
  EEA20662.1 110 ELLYGPPEDGLEYLRLVRSEANSLPALFVApKPKTEQKEIKQanealdqhgttkeeteqvqteTGYVVIDGVVIATSTSKEPteldieekrdaQSSYYN 208
                 55679*************************654443333223344455555555554445444333333333333334444433333333333556666 PP

        SIP1  74 eqladFselRqklsalreelqkkekkq..kiklp.kikdeek.wkefclgegnePllsillsldqvtveslleyliewleeeeelske.......laqW 161
                    + F  lR +l+      +    ++   i+lp ++k  +  w ++++    eP + +l+++d ++   +l+ l ++++  ++++++       +++W
  EEA20662.1 209 LLKHRFILLRTTLRCSPPATTIAGLDEshPITLPfHVKGARLaWTHLLYTT--EPQMAQLACMDMESTLGVLRLLGTVMS--KCVKDNdacqlrrIGAW 303
                 666666666666663222222222222454444414444444688888866..999999999999999999999988888..33333333445557888 PP

        SIP1 162 lyallavlekP..LdadtcsalRsllrkcaklRae 194
                  ++ll +      L ++ +  lR + rk+ ++ ++
  EEA20662.1 304 AWGLLGRCRDVgeLGSEEVGELRVFGRKALNILKK 338
                 88888776654346666666666666666666555 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.00066
        SIP1 200 eelamlnllitiigryFgQk 219
                 ++ + l+++iti+g+++gQk
  EEA20662.1 451 QSRILLDMIITIVGEFYGQK 470
                 4456699************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (480 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1303  (0.0726756); expected 358.6 (0.02)
Passed bias filter:                      534  (0.0297841); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.30s 00:00:00.98 Elapsed: 00:00:00.49
# Mc/sec: 2934.89
//
Query:       EEA20663.1  [L=567]
Description: aspartyl-tRNA synthetase Dps1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-65  221.8   0.1    1.4e-65  221.5   0.1    1.1  1  tRNA-synt_2      tRNA synthetases class II (D, K and N)
      1e-05   25.4   0.0    1.8e-05   24.6   0.0    1.5  1  tRNA_anti-codon  OB-fold nucleic acid binding domain
  ------ inclusion threshold ------
       0.15   12.4   0.1       0.32   11.3   0.1    1.5  1  DUF1570          Protein of unknown function (DUF1570)
       0.63    9.2   5.5       0.88    8.7   5.5    1.2  1  Med3             Mediator complex subunit 3 fungal


Domain annotation for each model (and alignments):
>> tRNA-synt_2  tRNA synthetases class II (D, K and N)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  221.5   0.1   3.1e-69   1.4e-65       3     313 ..     234     561 ..     232     562 .. 0.89

  Alignments for each domain:
  == domain 1  score: 221.5 bits;  conditional E-value: 3.1e-69
                  CHHHHTHHHHCCSHHHHHHHHHHHHHHHHHHHHHHHTT-EE----SEESS--SSSS--EEEEETTT.TEEE....-E-S-SHHHHHHHHHCTHSEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2   3 elrlknryldlrtekvskvlrlrstvtkavrkyleengfieietPiLsksdteegarlFkvksrekekeff....aLtqspqlylellivagidrvfq 96 
                  ++rl+nr+ldl+te  +++  + s v++++ +++ + g   i    Ls s te+g++ F v       ++f    +L+qspql +++ i++ ++ vf+
   EEA20663.1 234 KTRLDNRVLDLQTETSQAITWISSGVAQLFTEFMLKSGARWIFSSKLSGSSTEGGSEVFEV-------KYFnkkgYLAQSPQLMKQMAIAGDMESVFE 324
                  689**********************************************************.......55556667********************** PP

                  EEEEE--S--BTTB-S-CEEEEEEEEET-SCHH.HHHHHHHHHHHHHHHHHHCSCCCCCHTTTTTS.....EE-SSS.-EEEEHHHHHHHHHTS.... CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxx.xxxxxxxxxxxxxxxx.... RF
  tRNA-synt_2  97 iaraFRaEdsrtdrhlaEFtqieaemsfieeed.imqvleelikslvkevlessakdiefvirrns.....kdlkkp.fkrltykeaieklnei.... 183
                  ++++FRaE+s+t rhl+EFt +++e  f  + + +++++eel+  +++e++e+ +++i   +++       k +k+    rl+y + +  l+e     
   EEA20663.1 325 VGPVFRAENSNTHRHLTEFTGLDFEKTFRHHYHeVLDFAEELLVFILTELKERYKDEIAVIQKSYPkagdfKLPKDGkALRLNYMDGVALLKEAgvdt 422
                  ****************************987777****************888888887666665566665323332366**********99995555 PP

                  ......-SS--HHHHHHHHH...............HS--SEEEEEEEBGGGSTTCBBBSTTSTTBBSEEEEEETTEEEEEEEEB--SHHHHHHHHHHC CS
                  ......xxxxxxxxxxxxxx...............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2 184 ......gkdldkaderalvk...............keknepvfvtdfPaelkpFyarkeeddkkltesyDllingvElvgGslRiedpeeleeklksk 260
                        ++           +               k +++++ + +fP +++pFy++ + +d++ ++syD++++g E+++G++Ri+d +elee++ +k
   EEA20663.1 423 seqeafEN-----------DfttamekklgqiireKYDTDFYVLDRFPMAVRPFYTKADPEDPTFSHSYDFFMRGEEIMSGAQRINDVKELEESMIKK 509
                  55555533...........233444445555777699************************************************************* PP

                  CHHSSSGGGGHHHHHHHHCT--SEEEEEEEHHHHHHHHCT-SSGGGCSSS-XX CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2 261 gldeeaeekfswylealeyGapphgGlglGldRlvmlllgsesIrdviaFPkl 313
                  g+d  + e f++yl+a+++G+pph+G glGl+R+vm++lg++++r +++FP+ 
   EEA20663.1 510 GVD-PKTEGFEDYLNAFRQGCPPHAGGGLGLNRIVMFFLGLPNVRLATLFPRD 561
                  ***.999********************************************95 PP

>> tRNA_anti-codon  OB-fold nucleic acid binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.6   0.0   4.1e-09   1.8e-05       1      76 []     105     193 ..     105     193 .. 0.92

  Alignments for each domain:
  == domain 1  score: 24.6 bits;  conditional E-value: 4.1e-09
                      EEEEEEEEEEEEEEETTEEEEEEEETTEEEEEEEET.......HHHHHHHTTS-TTSEEEEEEEEEECTTS.......SEEEEEEEEEEE CS
  tRNA_anti-codon   1 VtvaGrvtsisdrsggkvifidlrDgtgriqvvlfr.......eeatklaenlkeGdvvrvtGrvkrrpgg.......elelkveeiell 76 
                      Vtv++rv +++  +++k+ f+ lr +  ++q v+          ++ k+   l ++++v+vtG  k+           elel++++i ++
       EEA20663.1 105 VTVVARVDNTR-SQSAKLGFLMLRQKGKKLQTVIAApaegpvsRQMVKWTTGLNVNSIVQVTGVAKKPAVPiasatltELELQITKIYMI 193
                      8*********8.999*****************************************************44455667889*******9875 PP

>> DUF1570  Protein of unknown function (DUF1570)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   7.2e-05      0.32      19      49 ..     244     274 ..     240     282 .. 0.93

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 7.2e-05
     DUF1570  19 vqsRladtpmWvsEGlaefFessklsegasw 49 
                 +q+  ++ ++W+s G+a++F    l +ga+w
  EEA20663.1 244 LQTETSQAITWISSGVAQLFTEFMLKSGARW 274
                 78899*************************9 PP

>> Med3  Mediator complex subunit 3 fungal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   5.5    0.0002      0.88     177     229 ..      20      72 ..       5     187 .. 0.71

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0002
        Med3 177 tpt.nsaaaaattatttssqa.kkPrkPrqtkkaaakaaakaqaqaqaqaqaqqq 229
                   t n+a+aa   a ++s +a kk  k +   ka+ +aa  aq+qaq+ a a ++
  EEA20663.1  20 PATeNAAPAAEGGAAAPSKSAlKKAAKEKA--KAEKAAARAAQEQAQKAASAAAD 72 
                 223366677766676776665244444332..33333333456666655555443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (567 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1130  (0.0630264); expected 358.6 (0.02)
Passed bias filter:                      647  (0.0360868); expected 358.6 (0.02)
Passed Vit filter:                        80  (0.00446204); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.72u 0.31s 00:00:01.03 Elapsed: 00:00:00.49
# Mc/sec: 3490.38
//
Query:       EEA20664.1  [L=405]
Description: HAD superfamily hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.6e-24   83.9   0.0    1.1e-23   83.3   0.0    1.4  1  Hydrolase_6     Haloacid dehalogenase-like hydrolase
    3.6e-18   65.4   0.0    2.1e-17   62.9   0.0    2.3  3  Hydrolase_like  HAD-hyrolase-like
    1.3e-05   25.6   0.0     0.0018   18.6   0.0    2.9  2  Hydrolase       haloacid dehalogenase-like hydrolase
     0.0048   16.7   0.0     0.0068   16.2   0.0    1.2  1  Hydrolase_3     haloacid dehalogenase-like hydrolase
     0.0068   16.5   0.0        1.7    8.7   0.0    2.5  3  HAD_2           Haloacid dehalogenase-like hydrolase
  ------ inclusion threshold ------
       0.13   12.7   0.0        5.2    7.4   0.0    3.2  4  HAD             haloacid dehalogenase-like hydrolase


Domain annotation for each model (and alignments):
>> Hydrolase_6  Haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.3   0.0   3.6e-27   1.1e-23       1     101 []      47     155 ..      47     155 .. 0.92

  Alignments for each domain:
  == domain 1  score: 83.3 bits;  conditional E-value: 3.6e-27
                  EEEESTTTSEETTEE-TTHHHHHHHHHHTT-EEEEEE---SS-HHHHHHHH.HHTT----GGGEEEHHHHHHHHHHHHSX......XXEEEEESXH.. CS
  Hydrolase_6   1 flfDidGvLwrgdkaipgaaealnalraagkpvvllTNnsskseeeyakkl.eklgvditeeqvvtsataaaeylkkrka......dkkvlvigee.. 89 
                  f+fDidGvL+r +k+ipga +al++l+++g+p++llTN+++k+e e+++++ ekl++ ++++ +++s++++ae+++ + +      +k++lv g++  
   EEA20664.1  47 FAFDIDGVLLRSSKPIPGASDALRTLQERGIPFILLTNGGGKHETERVAEIsEKLNITLDPSVIIQSHSPFAELVNGA-FgqealeHKTILVAGGDgd 143
                  78*********************************************9999999**********************94.3356666*********844 PP

                  HHHHHHHHTTXE CS
  Hydrolase_6  90 glreelkeagfk 101
                  ++r +++++gfk
   EEA20664.1 144 NCRLVAEKYGFK 155
                  6999******97 PP

>> Hydrolase_like  HAD-hyrolase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0       2.5   7.4e+03      42      57 ..      76      91 ..      73     104 .. 0.66
   2 ?   -1.9   0.0       1.2   3.5e+03      44      61 ..     133     150 ..     128     159 .. 0.62
   3 !   62.9   0.0     7e-21   2.1e-17       2      74 ..     307     394 ..     306     395 .. 0.87

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 2.5
                    T-EEEEESSSSS-TTT CS
  Hydrolase_like 42 GwksvLVltGvtrped 57
                    G+ ++L + G  ++e 
      EEA20664.1 76 GIPFILLTNGGGKHET 91
                    8888998887655544 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 1.2
                     EEEEESSSSS-TTTHHHH CS
  Hydrolase_like  44 ksvLVltGvtrpedleep 61 
                     k++LV+ G  ++ +l ++
      EEA20664.1 133 KTILVAGGDGDNCRLVAE 150
                     677777777666555444 PP

  == domain 3  score: 62.9 bits;  conditional E-value: 7e-21
                     .STTSSHHHHHHHHHH............---.GGGEEEEES-TTTHHHHHHHCT......-EEEEESSSSS-TTTHHHHHHHHT---SEEES CS
  Hydrolase_like   2 lgKPepemydfalevl............gsd.peevlmiGDrlatDiagAnnaG......wksvLVltGvtrpedleepehkptyvaddlae 74 
                     +gKP + +y+fa ++l              +  ++v+miGD++++Di+gAn +       w+s+LV+tGv++ +    p+++pt +add++ 
      EEA20664.1 307 VGKPYALTYRFAENQLlrnrskifdhegL-PpIRNVFMIGDNPESDIRGANTYNseygskWHSILVRTGVYSGGT---PAYQPTTIADDVKH 394
                     6***************8888888877743.34899****************987666677*************77...78*********986 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0   6.1e-07    0.0018      93     156 ..      39      99 ..      29     165 .. 0.79
   2 ?    3.7   0.0     0.022        66     171     206 ..     307     355 ..     279     358 .. 0.70

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 6.1e-07
                 HHHHCHHHHHHTTHHHHHHHHHHTHHBHTTHHHHHHHHHHTTEEEEEEE.SSEHHHHHHHHHHTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxx RF
   Hydrolase  93 aqsqgrtvallqaralavftiadplkvkpeaaeavasLkaagievvllt.gdnpetaeraanqlG 156
                 a ++  +++    ++++v+  + +  + p+a +a+++L+++gi+ +llt g+ ++  er+a+   
  EEA20664.1  39 ATEAPDIAFAF--DIDGVLLRSSK--PIPGASDALRTLQERGIPFILLTnGGGKHETERVAEISE 99 
                 55555556666..78888888988..***********************4444555558888766 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.022
                 STTTSHHHHHHHHHHH..T..........STGGGEEEEESSHH.HHHHH CS
                 xxxxxxxxxxxxxxxx..x..........xxxxxxxxxxxxxx.xxxxx RF
   Hydrolase 171 vakpspegkvaaireL..q..........gkpeevamVGDgvn.Daaal 206
                 v+kp    ++ a ++L  +           ++++v m+GD++  D+ ++
  EEA20664.1 307 VGKPYALTYRFAENQLlrNrskifdheglPPIRNVFMIGDNPEsDIRGA 355
                 5555555555555555331344444444456899********9999876 PP

>> Hydrolase_3  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   2.3e-06    0.0068       1      55 [.      47     104 ..      47     137 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 2.3e-06
                  EEEEIIIIIS-TTS---HHHHHHHHHHHHTTSEEEEE-...SS.-HHHHHHHHHHCCCC CS
  Hydrolase_3   1 ialDlDGTLlnsdkkisektkeaikklkekgikvviAT...GR.slravlpvleelgld 55 
                  +a+D+DG Ll+s k i + + +a++ l+e+gi +++ T   G  +++ v ++ e+l+++
   EEA20664.1  47 FAFDIDGVLLRSSKPI-PGASDALRTLQERGIPFILLTnggGKhETERVAEISEKLNIT 104
                  59************99.7889**************988433333455566666666665 PP

>> HAD_2  Haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0      0.81   2.4e+03       3      12 ..      49      58 ..      45      60 .. 0.85
   2 !    8.7   0.0   0.00057       1.7      77     117 ..      58      98 ..      50     158 .. 0.76
   3 !    5.0   0.0    0.0078        23     154     172 ..     340     359 ..     328     363 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.81
       HAD_2  3 FDlDgTlldt 12
                FD+Dg+ll +
  EEA20664.1 49 FDIDGVLLRS 58
                *******865 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.00057
       HAD_2  77 evkpydgvkelLeeLkeagyklgivTsksreaveekleqlg 117
                 + kp++g+ ++L +L+e+g+   + T++  +  +e ++++ 
  EEA20664.1  58 SSKPIPGASDALRTLQERGIPFILLTNGGGKHETERVAEIS 98 
                 579************************98777777666654 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.0078
       HAD_2 154 eviyvGDsp.tDieaakkag 172
                 +v+++GD+p +Di +a   +
  EEA20664.1 340 NVFMIGDNPeSDIRGANTYN 359
                 799*************8765 PP

>> HAD  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.0    0.0018       5.2      79     111 ..      57      87 ..      12     105 .. 0.76
   2 ?   -0.8   0.0      0.57   1.7e+03      99     128 ..     129     158 ..     124     175 .. 0.86
   3 ?   -1.3   0.0      0.85   2.5e+03       7      66 ..     234     293 ..     234     300 .. 0.72
   4 ?   -0.6   0.0      0.52   1.6e+03     153     184 ..     320     352 ..     297     355 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0018
         HAD  79 evirpklldpgalellaahraaGdrvvvvSgg.l 111
                 +  +p    pga ++l+  +++G++++++++g  
  EEA20664.1  57 RSSKPI---PGASDALRTLQERGIPFILLTNGgG 87 
                 445555...9*******999**********8734 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.57
         HAD  99 aaGdrvvvvSgglrplvepllaelgadevl 128
                 a  +++++v gg   + + +++++g++ v+
  EEA20664.1 129 ALEHKTILVAGGDGDNCRLVAEKYGFKSVV 158
                 567999999999999**********88876 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.85
         HAD   7 gTLldgdslelllrfllrrgaprlwralreklllalfrellrldraglaelleallagls 66 
                 gTL d++  ++l  + +++++ + +   ++ l+ a  ++l rl + g++e+le ++a+ +
  EEA20664.1 234 GTLSDKNGKPELPNRGYQQDGQPPLYFSNPDLWWAASYHLPRLGQGGFREALEGTWAAVT 293
                 566666666666666666666666666777777777889999999999999999988766 PP

  == domain 4  score: -0.6 bits;  conditional E-value: 0.52
         HAD 153 gkvaalrewlaaegegidleevvayGDsp.sDl 184
                 + + + r+++++++  +++ +v+ +GD p sD+
  EEA20664.1 320 NQLLRNRSKIFDHEGLPPIRNVFMIGDNPeSDI 352
                 445555668899999999999******886666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (405 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       292  (0.0162865); expected 358.6 (0.02)
Passed bias filter:                      287  (0.0160076); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 2784.85
//
Query:       EEA20665.1  [L=323]
Description: NAD dependent epimerase/dehydratase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      3e-20   72.7   0.0    3.9e-20   72.4   0.0    1.1  1  Epimerase        NAD dependent epimerase/dehydratase family
      1e-08   34.7   0.1    1.4e-08   34.2   0.1    1.1  1  RmlD_sub_bind    RmlD substrate binding domain
    1.9e-06   27.9   0.4    2.7e-06   27.4   0.4    1.3  1  NAD_binding_10   NAD(P)H-binding
    1.2e-05   24.5   0.0    3.3e-05   23.0   0.0    1.6  1  3Beta_HSD        3-beta hydroxysteroid dehydrogenase/isomeras
    1.8e-05   24.4   0.1    3.3e-05   23.5   0.1    1.4  1  NmrA             NmrA-like family
    6.5e-05   22.2   0.0    0.00055   19.1   0.0    2.0  2  Polysacc_synt_2  Polysaccharide biosynthesis protein
      8e-05   22.2   0.7    0.00088   18.8   0.7    2.2  1  GDP_Man_Dehyd    GDP-mannose 4,6 dehydratase
  ------ inclusion threshold ------
      0.027   13.6   0.4        5.4    6.1   0.1    2.3  2  NAD_binding_4    Male sterility protein
      0.056   13.3   0.2        0.4   10.5   0.0    2.0  2  DFP              DNA / pantothenate metabolism flavoprotein
       0.08   12.9   0.2       0.78    9.7   0.1    2.2  2  ADH_zinc_N       Zinc-binding dehydrogenase


Domain annotation for each model (and alignments):
>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.4   0.0   2.2e-23   3.9e-20       1     240 [.       9     229 ..       9     230 .. 0.85

  Alignments for each domain:
  == domain 1  score: 72.4 bits;  conditional E-value: 2.2e-23
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC..EEEE--TT-HHHHHHHHHHHT-SEEEE--S---HHHHHHSHHHHHHHHTHHHHH CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl..elveldltdrsalerlfkeeqpdavihlAavggvaassedpadfieknlqgtln 97 
                 i++tGa+G++Gs +++   ++gy+v+gl+r + ++++ +   l    v++dl   + l+r  +  +++++ihl   ++v++++ d ++ +  ++  +  
  EEA20665.1   9 IFMTGASGYLGSVITELAIAQGYKVHGLSRTEANDAKLKG--LgaVPVRGDLEALDVLRRESA--NAQIIIHL---ADVMTRNPDYSAGLCVDATAVDA 100
                 789****************************554444444..45699*************888..99******...6677777777777889******* PP

                 HHHHHHHHTCTEEEEEEEGGGGTSCSSSSBSTCSTTS----SSHHHHHHHHHHHHHHHHHHHHT-EEEEEEES.EEESTTS-TTSTTSHHHHHHHHHHT CS
   Epimerase  98 lleaarkagvkrllflsSsevYGkdaeqpkeettltgplkpnspYaaaKlageklveayaaqyglnaiilrlf.nlyGprngegevsrvipalirkile 195
                 ++e++r ++   ll  s s +  ++++   eett+t+pl+ n    + K+ ++ +++a  ++  +++i++rl   +yG +      s+v  +l  ++++
  EEA20665.1 101 ICEVVRGTNK-PLLVTSGSLLVEANPN--GEETTETSPLQKNPVNQRWKAEAHAMTWA--REKSVRVISIRLApYVYGRG-----GSGV--RLFMQMHA 187
                 ******9999.6666666677776666..8*********999999********99996..666689****996269***9.....6666..66677777 PP

                 TSSSEEEETTST-EEEEEEHHHHHHHHHHHHHHHTT-STTEEEEE CS
   Epimerase 196 gkqevtllgdgtalRdflyveDvaeaillvlehvdagdkgeiyni 240
                 +  evt ++dg+a+   ++v+D+a+++ll++++     +g+++n+
  EEA20665.1 188 RNGEVTCIDDGSARTSTIHVDDAARMYLLAAKK---AGAGDVFNC 229
                 7778*****************************...566788886 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.2   0.1   7.7e-12   1.4e-08       2     227 ..       8     244 ..       7     257 .. 0.78

  Alignments for each domain:
  == domain 1  score: 34.2 bits;  conditional E-value: 7.7e-12
                    EEEEESTTSHHHHHHHHHCTTTSEEEEEE-TTT--TTSHHHHHHHH.............HHH--SEEEE------HHHHHHSHHHHHHHHTHHHHH CS
  RmlD_sub_bind   2 kilvtGanGqlGseLakqlaeeglevlaltreeldltdaeavaell.............keakpdvvvnaAAytavDkaEseeeaayavnaeavea 84 
                    +i +tGa+G lGs +++++ ++g++v++l+r+e++ ++ + + ++              ++a+ ++++++A   +v     +  a   v+a+av a
     EEA20665.1   8 RIFMTGASGYLGSVITELAIAQGYKVHGLSRTEANDAKLKGLGAVPvrgdlealdvlrrESANAQIIIHLA---DVMTRNPDYSAGLCVDATAVDA 100
                    799*****************************6665555555555455555666666656778999****9...7778888999999********* PP

                    HHHHHHHCT-EEEEEEEGGGS-S-TTS-.B-TTS..----SSHHHHHHHHHHHHHHHH-SSEEEEEE-.SEESSSSS-HHHHHHHHHHH-SEEEEE CS
  RmlD_sub_bind  85 lAeaaaavgalLihvStDyVFdGekkrp.Yeedd..etsPlnvYGrtKlaGEqavlaagkkalivRts.wvygekgknfvktmlrlakereelkvv 176
                    + e+ + ++ +L+  S     +++ + +  +e++  +++P+n + ++ ++   + ++++ +++ +R + +vyg+ g      ++++ +++ e++ +
     EEA20665.1 101 ICEVVRGTNKPLLVTSGSLLVEANPNGEeTTETSplQKNPVNQRWKAEAHAMTWAREKSVRVISIRLApYVYGRGGSGVR-LFMQMHARNGEVTCI 195
                    ***********************9555325555522467888888888888899999999******9758***9877755.555666677788888 PP

                    SS-E.E--E.EHHHHHHHHHHHHHHCHH.GGG-EEEE---BS-EEHHHHHHHH CS
  RmlD_sub_bind 177 aDql.gsPT.sardlAevllqllekaaeekelagvyHlanegetswlefArai 227
                    +D   ++ T +++d A++ l +++ka +      v+ ++++ +++ l +A+a+
     EEA20665.1 196 DDGSaRTSTiHVDDAARMYLLAAKKAGA----GDVFNCTSSTNVTALHLAQAM 244
                    8865155552456666666655555554....99****************986 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.4   0.4   1.5e-09   2.7e-06       1     156 [.      13     181 ..      13     221 .. 0.80

  Alignments for each domain:
  == domain 1  score: 27.4 bits;  conditional E-value: 1.5e-09
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHHCTTTCEEEE--TT-CCHHHHHHTT-SEEEES-.....--TCC........HHHHHHHHH CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpeklaeleaeeglevvegdvtdvedlaealkgadaVvsal.....ggggk........deegakniv 82 
                     GA+G  G+ +++ ++a+ g++v+ l R+++  a+l+   g+  v gd++  + l++  ++a++++  +     +            d++++++i+
      EEA20665.1  13 GASGYLGSVITELAIAQ-GYKVHGLSRTEANDAKLK-GLGAVPVRGDLEALDVLRRESANAQIIIHLAdvmtrN---PdysaglcvDATAVDAIC 102
                     9****************.5*********99999997.699***********************99999775431...3455667778888***** PP

                     HHHHHCT--EEEEEEETTTTSGCGCH....HHHHHHHCCHHHHHHHHHHHHHHHHSSSEEEEEEE-CEE-ST.--SEEE CS
  NAD_binding_10  83 daakeagvkRfvlvsaigvgdevpge....fgewnkellkaylaakraaeellrasgldwTivrpggLtdep.ttkyrv 156
                     ++++ ++   +v+ +++ v+ + +ge    +++++k+ +++ ++a ++a  + r++ +    +r +    +  ++++r+
      EEA20665.1 103 EVVRGTNKPLLVTSGSLLVEANPNGEetteTSPLQKNPVNQRWKAEAHAMTWAREKSVRVISIRLAPYVYGRgGSGVRL 181
                     ***9999999999999999874443322115666677788888899999999999999888888877666653445555 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.0   0.0   1.8e-08   3.3e-05       2     231 ..      11     220 ..      10     226 .. 0.75

  Alignments for each domain:
  == domain 1  score: 23.0 bits;  conditional E-value: 1.8e-08
   3Beta_HSD   2 vtGgaGFlGralvkeLvrleelkevrvlDlrespelleelskvnvkkviegDvtdkdkleealegvdvvihlaslvdvagkltedeimkvnvkGTrnvl 100
                 +tG++G+lG+ + +  +  +   +v+ l   e +    +l+ ++    + gD+   d l++   +++++ihla ++     ++ + + ++       + 
  EEA20665.1  11 MTGASGYLGSVITELAIAQG--YKVHGLSRTEANDA--KLKGLGAV-PVRGDLEALDVLRRESANAQIIIHLADVMTRNPDYSAGLCVDA--TAVDAIC 102
                 69*******99998888888..46666655555555..88999999.9************************888877778888866554..3344555 PP

   3Beta_HSD 101 eacvkagvrvlvYtSsaevvgpnslgeeilngdEeleyeslhqdayp.esKalaEklvlkaNgrtlknggrlyTcaLRpagiyGegdkllvpllkqlak 198
                 e  + ++ + lv   s+ v  +        ng+E++e  +l +++ + + Ka a ++   a ++ +    r++ + L   ++yG g + +  +++  a+
  EEA20665.1 103 EVVRGTNKPLLVTSGSLLVEAN-------PNGEETTETSPLQKNPVNqRWKAEAHAMTW-AREKSV----RVISIRLA-PYVYGRGGSGVRLFMQMHAR 188
                 5555555566665555555444.......577777777777666655156777776655.444233....45555554.59*************99999 PP

   3Beta_HSD 199 lglalfkigdeevlsdrvYvgNvawahilAara 231
                 +g ++  i d ++ ++ + v+  a +++lAa++
  EEA20665.1 189 NG-EVTCIDDGSARTSTIHVDDAARMYLLAAKK 220
                 99.888999**********************97 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   0.1   1.9e-08   3.3e-05       1      75 [.       9      81 ..       9     105 .. 0.80

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 1.9e-08
                EEESSTTSHHHHHHHHHHHHHT-EEEEEES-S-SHHHHHHHHSTTEEEES-TT-HHHHHHHHTT-SEEEE---GG CS
        NmrA  1 IlviGaTGrqGksvvrallkaghkvralvRdtkselakslkeaGvelvkgdlddkeslvealkgvdvvfsvtgfy 75
                I  +Ga+G++G+ +++ ++++g+kv  l R + ++  ++lk  G++ v gdl+  ++l++   +++ ++    ++
  EEA20665.1  9 IFMTGASGYLGSVITELAIAQGYKVHGLSRTEAND--AKLKGLGAVPVRGDLEALDVLRRESANAQIIIHLADVM 81
                6789**************************87655..69**************9999999999999998776655 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0      0.12   2.1e+02       1      37 [.       9      44 ..       9      84 .. 0.72
   2 !   19.1   0.0   3.1e-07   0.00055     159     247 ..     158     248 ..     143     260 .. 0.84

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.12
                     EEEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHH CS
  Polysacc_synt_2  1 vlvtGagGsiGselvrqilkkkpkkiillerdElkly 37
                     +++tGa+G +Gs +++  +++   k+  l+r+E +  
       EEA20665.1  9 IFMTGASGYLGSVITELAIAQ-GYKVHGLSRTEANDA 44
                     6789*******9887766555.445555566665544 PP

  == domain 2  score: 19.1 bits;  conditional E-value: 3.1e-07
                      S--EEEEEEE-.EETTGTTSSHHHHHHHHHTTSSEEES-TT-EEE.EE-HHHHHHHHHHHHHH--SS-EEEE--.-EEEHHHHHHHH.... CS
  Polysacc_synt_2 159 kktkfvvvRfG.NVlgSrGSviplFkkqikeggpvtvTdpemtRy.fmtieeavqLvlqalalakggeifvldmGepvkivdlakaliels 247
                      k+ +++ +R    V g  GS + lF +  +++g+vt  d    R   + +++a+++ l a+++a  g++f       v+ ++la+a+ ++ 
       EEA20665.1 158 KSVRVISIRLApYVYGRGGSGVRLFMQMHARNGEVTCIDDGSARTsTIHVDDAARMYLLAAKKAGAGDVFNCTSSTNVTALHLAQAMGSIL 248
                      4577777777525788889*****************9999888853799*************************9***********97765 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.7   4.9e-07   0.00088       2     253 ..      11     234 ..      10     291 .. 0.69

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 4.9e-07
                    EETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHHHHT-SEEEE--S---HHHHTTSHHH CS
  GDP_Man_Dehyd   2 iTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkgDltDssslerllaevqpdevynLAAqshVdvsfekPey 97 
                     TG +G+ Gs ++el +++gy+vhg+ r +++   ++++ l   p          ++gDl+  + l+r  a++  + +++LA     dv   +P+y
     EEA20665.1  11 MTGASGYLGSVITELAIAQGYKVHGLSRTEAN--DAKLKGLGAVP----------VRGDLEALDVLRRESANA--QIIIHLA-----DVMTRNPDY 87 
                    6************************9887665..45777776544..........788888888888866665..5689998.....667777777 PP

                    HHH..HHTHHHHHHHHHHHHCT..TTSEEEEEEEGGGG-S-.SSSSB-TTS-----SHHHHHHHHHHHHHHHHHHHH---EEEEEE-EEESTTS-T CS
  GDP_Man_Dehyd  98 tae..vnvlGtlrLLeairalglekkvrfyqaStsEvYGkv.qevpqtEttpfyPrsPYaaaKlyadwivvnyreayglfavngilfnhesprrge 190
                     a   v+++++  + e++r ++    + ++ +S s +     +    tEt p++ +      K+ a+ ++  + ++  + +++ +l      r g 
     EEA20665.1  88 SAGlcVDATAVDAICEVVRGTN----KPLLVTSGSLLVEANpNGEETTETSPLQKNPVNQRWKAEAHAMT--WAREKSVRVISIRLAPYVYGR-GG 176
                    7652255566667777777654....24555555555444404455788888888888888888888777..445555666666666655555.44 PP

                    TSCCCHHHHHHHHHHTTS-C-EECTTTT-EEEEEEHHHHHHHHHHHHHCSS---EEE-TT-EE CS
  GDP_Man_Dehyd 191 tfvtrkitravarialgkqevlylGnldakRdwghvkDyveamwlmlqqdkpedyviatgeth 253
                    + v r+++++ ar    + ev+ + +++a+ +  hv+D ++++ l+ ++  + d+  +t  t 
     EEA20665.1 177 SGV-RLFMQMHAR----NGEVTCIDDGSARTSTIHVDDAARMYLLAAKKAGAGDVFNCTSSTN 234
                    444.566555443....4445666888888888888888888888888877777776665554 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.1     0.003       5.4       2      35 ..      12      43 ..      11      52 .. 0.77
   2 ?    5.5   0.0    0.0045         8      82     163 ..      65     143 ..      51     160 .. 0.69

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.003
                   E-TTSHHHHHHHHHHHHHS-.TEEEEEE-SSSHH CS
  NAD_binding_4  2 TGaTGFLGkvLlekLLrttpevkiyllvRaksge 35
                   TGa+G+LG+v+ e  + +    k++ l R++ ++
     EEA20665.1 12 TGASGYLGSVITELAIAQGY--KVHGLSRTEAND 43
                   **********9886666654..888888877665 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.0045
                    HHHHHH--EEEE--SS-S.STTSSEEHHHHHHHHHHHHHHHTSSS--.-EEEEEE.GGGTTS-TTT--SSS-H......HHH- CS
  NAD_binding_4  82 qelaeevdviihsaAtvnfdepykellrvNveGtrevlelakklkklkvllhvST.ayvngeregeveekvyeegekeeklde 163
                    ++ +++ ++iih a  ++ + +y+  l v  +++  ++e  ++++k   ll  S    v+ + +ge  e++  ++ +++ +++
     EEA20665.1  65 RRESANAQIIIHLADVMTRNPDYSAGLCVDATAVDAICEVVRGTNKP--LLVTSGsLLVEANPNGE--ETTETSPLQKNPVNQ 143
                    5567899*********************************9977555..66666524444444444..333333333333333 PP

>> DFP  DNA / pantothenate metabolism flavoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00023       0.4      21      92 ..       8      80 ..       5      90 .. 0.87
   2 ?    0.3   0.0       0.3   5.4e+02      30      86 ..     176     227 ..     172     233 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00023
                EEEEE----HHHHHHHHHHHHTT-EEEEEE-S-.SS---TT-EEEE--SHHHHHHHHHHHHTT-SEEEE---S CS
         DFP 21 RfisNrSSGkmGyalAeaaaarGaeVtlvsgpv.sletpegvevvkvesaeemleaveealkeadivimaAAv 92
                R++   +SG  G  + e a+a+G +V+  s    + ++ +g+  v v+   e l+ ++++ ++a+i+i+ A v
  EEA20665.1  8 RIFMTGASGYLGSVITELAIAQGYKVHGLSRTEaNDAKLKGLGAVPVRGDLEALDVLRRESANAQIIIHLADV 80
                6777789**********************9985244456799**************************99977 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.3
                 HHHHHHHHHHHHTT-EEEEEE-S-SS---TT-EEEE--SHHHHHHHHHHHHTT-SEE CS
         DFP  30 kmGyalAeaaaarGaeVtlvsgpvsletpegvevvkvesaeemleaveealkeadiv 86 
                   G+ l  ++ ar  eVt +   +     +++++++v++a+ m+  + +++ + d++
  EEA20665.1 176 GSGVRLFMQMHARNGEVTCIDDGS-----ARTSTIHVDDAARMYLLAAKKAGAGDVF 227
                 567777777888888888887662.....3467899******999998888877876 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.1   0.00044      0.78       2      37 ..      18      53 ..      18      79 .. 0.91
   2 ?    0.7   0.0      0.26   4.7e+02      30      72 ..     218     234 ..     187     272 .. 0.67

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00044
                HHHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTESE CS
  ADH_zinc_N  2 vGlaavqlAkalGaeviavdsseeklelakklGade 37
                +G+   +lA a G +v++ +++e + +++k lGa  
  EEA20665.1 18 LGSVITELAIAQGYKVHGLSRTEANDAKLKGLGAVP 53
                69999****************************965 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.26
                 HHHTTESEEEETTTCHHHHHHHHHTTTSSEEEEEESSCSHHHH CS
  ADH_zinc_N  30 akklGadevinykeadlverikeltggegvdvvfecvGsgatl 72 
                 a                        ++ g+  vf+c+   +t 
  EEA20665.1 218 A------------------------KKAGAGDVFNCTS--STN 234
                 2........................3445555555555..233 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (323 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       451  (0.0251548); expected 358.6 (0.02)
Passed bias filter:                      408  (0.0227564); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.58u 0.33s 00:00:00.90 Elapsed: 00:00:00.51
# Mc/sec: 1905.82
//
Query:       EEA20666.1  [L=507]
Description: Leucine Rich Repeat domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.1e-08   32.9   4.9    4.1e-08   32.9   4.9    2.2  3  LRR_8     Leucine rich repeat
    0.00029   21.1   2.9    0.00029   21.1   2.9    3.5  4  LRR_4     Leucine Rich repeats (2 copies)


Domain annotation for each model (and alignments):
>> LRR_8  Leucine rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.1      0.35   3.1e+03      31      50 ..     197     216 ..     194     219 .. 0.48
   2 !   32.9   4.9   4.5e-12   4.1e-08       5      61 .]     241     295 ..     240     295 .. 0.98
   3 ?   -4.1   0.0       1.6   1.5e+04      49      56 ..     400     407 ..     396     408 .. 0.58

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.35
                 E--SS---GGGGGGGTT--S CS
       LRR_8  31 dLsnNllttlspgafsgLps 50 
                 dLsn  l+ +  + ++ L +
  EEA20666.1 197 DLSNFGLKNIPTDLLRPLLH 216
                 55555555555555444433 PP

  == domain 2  score: 32.9 bits;  conditional E-value: 4.5e-12
                 EEE-TTS--SEE-TTSSTT-TT--EEE--SS---GGGGGGGTT--S-.EEE--SS-- CS
       LRR_8   5 sLdLsnNrltslddeaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 
                 +L Ls N+l++l  e F+ l nL+vL+ +nN+l  + pga++ L+sL++++Ls N+L
  EEA20666.1 241 RLFLSGNSLKELTSEIFE-LGNLNVLSVRNNELVEI-PGAIRKLTSLQEINLSVNQL 295
                 599***************.*****************.9*****************98 PP

  == domain 3  score: -4.1 bits;  conditional E-value: 1.6
                 -S-.EEE- CS
       LRR_8  49 psLrsLdL 56 
                 psLr+L L
  EEA20666.1 400 PSLRELAL 407
                 56666544 PP

>> LRR_4  Leucine Rich repeats (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.2      0.18   1.6e+03       5      19 ..     195     211 ..     194     219 .. 0.63
   2 !   11.2   0.9   4.5e-05      0.41       6      39 ..     242     275 ..     240     280 .. 0.88
   3 !   21.1   2.9   3.3e-08   0.00029       2      39 ..     261     298 ..     260     328 .. 0.93
   4 ?   -3.2   0.0       1.5   1.4e+04      23      32 ..     400     409 ..     392     412 .. 0.68

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.18
                 EEE--SS---E-S-..H CS
       LRR_4   5 vLdLsnNqltdipl..l 19 
                 ++dLsn  l+ ip   l
  EEA20666.1 195 SVDLSNFGLKNIPTdlL 211
                 57888778888877543 PP

  == domain 2  score: 11.2 bits;  conditional E-value: 4.5e-05
                 EE--SS---E-S-..HHH-TT--EEE-.-S-----G CS
       LRR_4   6 LdLsnNqltdipl..leklpnLkeLdLsgNnlitdl 39 
                 L Ls+N l+++ +  +e l nL +L++ +Nn +  +
  EEA20666.1 242 LFLSGNSLKELTSeiFE-LGNLNVLSV-RNNELVEI 275
                 99***********9888.*********.98888666 PP

  == domain 3  score: 21.1 bits;  conditional E-value: 3.3e-08
                 S--EEE--SS---E-S-.HHH-TT--EEE-.-S-----G CS
       LRR_4   2 nLevLdLsnNqltdipl.leklpnLkeLdLsgNnlitdl 39 
                 nL vL+ +nN l +ip+ ++kl++L+e++L + n++t++
  EEA20666.1 261 NLNVLSVRNNELVEIPGaIRKLTSLQEINL-SVNQLTTI 298
                 899**************9889*********.55599998 PP

  == domain 4  score: -3.2 bits;  conditional E-value: 1.5
                 TT--EEE-.- CS
       LRR_4  23 pnLkeLdLsg 32 
                 p+L+eL L  
  EEA20666.1 400 PSLRELALLA 409
                 7888886644 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (507 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       547  (0.0305092); expected 358.6 (0.02)
Passed bias filter:                      458  (0.0255452); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 3234.15
//
Query:       EEA20667.1  [L=296]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-13   51.0   3.3    2.9e-13   50.5   3.3    1.3  1  EI24      Etoposide-induced protein 2.4 (EI24)


Domain annotation for each model (and alignments):
>> EI24  Etoposide-induced protein 2.4 (EI24)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.5   3.3   1.6e-17   2.9e-13       1     177 [.      31     263 ..      31     264 .. 0.64

  Alignments for each domain:
  == domain 1  score: 50.5 bits;  conditional E-value: 1.6e-17
                 HHHHHHHHHTS.TTTHHHHHHHHHHHHHHHHHHHHHHH-TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH...................... CS
        EI24   1 allrglglllsspkllallllplllnlllfllllvlllwvllasllvllllllplwlfplvalllaapfygllaekv...................... 77 
                 ++++g+ ++ls++ l+a l   l  +l+l +            s+ + l+ll +++ ++l+a l ++pf+  +++++                      
  EEA20667.1  31 YPFKGIIYILSHRTLWAPLRSRLMPTLALGV------------SITTALFLLTYIPQMTLLA-LTSGPFVAPISAALlvineasaitgflasrnmffgl 116
                 57899***********999888888888877............3333333333333332222.223333333333333444333333555544466666 PP

                 .......................HH.HH................CCTTSHH...........HHHHHHHHHHHHHHHHHHH.HHTTHHH....HHHHHH CS
        EI24  78 .......................ekrhl................glvksla...........eslkslllllllllvllpl.liPvvglilsplllswl 125
                                        +                    +++++l+           +s  s+l  l++ l+ lpl +iPvvg++++++l +  
  EEA20667.1 117 gqsssstssltldafdatlmlkgH---EklvsggreiklpsragNVLTRLGglvgmskrnsfNSSGSTLDSLIRSLLYLPLnFIPVVGTFAFLALKGKR 212
                 555555454444444444444441...0344555555666667744444445555556766789999999999999*****999****87777766654 PP

                 HHHHHHHHHHHHHHHH...-HHHHHHHHHCTHHHHHHHHHHHHHHTTSCCHHCTH CS
        EI24 126 tayfycfeyldlaagr...sleerrallerrrayflgfGllvslllliPllnllf 177
                     ++  +ld+++++   s +er ++l+++ + +++fG++ s+l ++P+ +++f
  EEA20667.1 213 ----MGRNALDRYFELkgySASEREEWLKAHEGDYISFGVASSVLEMVPFASFIF 263
                 ....666777777777777********************************9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (296 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       343  (0.019131); expected 358.6 (0.02)
Passed bias filter:                      232  (0.0129399); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.29s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 2071.43
//
Query:       EEA20668.1  [L=829]
Description: PA and RING finger domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.4e-13   49.0   5.5    8.6e-13   48.4   5.5    1.3  1  zf-RING_2     Ring finger domain
    6.1e-09   35.5   2.7    6.1e-09   35.5   2.7    1.9  2  zf-RING_11    RING-like zinc finger
    6.1e-09   35.6   4.9      1e-08   34.9   4.9    1.4  1  zf-C3HC4_2    Zinc finger, C3HC4 type (RING finger)
    8.4e-09   35.3   0.0    1.9e-08   34.2   0.0    1.6  1  PA            PA domain
    9.5e-09   35.4   3.0    2.1e-08   34.3   3.0    1.5  1  zf-rbx1       RING-H2 zinc finger domain
    1.6e-08   34.2   3.9    2.7e-08   33.6   3.9    1.4  1  zf-C3HC4      Zinc finger, C3HC4 type (RING finger)
    1.6e-07   31.2   3.1    2.4e-07   30.6   3.1    1.3  1  zf-RING_5     zinc-RING finger domain
    3.3e-06   26.9   3.1    4.9e-06   26.3   3.1    1.3  1  zf-C3HC4_3    Zinc finger, C3HC4 type (RING finger)
    5.2e-06   26.4   2.0    1.2e-05   25.3   0.5    2.2  2  zf-RING_UBOX  RING-type zinc-finger
      0.001   19.1   1.0      0.002   18.1   1.0    1.4  1  zf-ANAPC11    Anaphase-promoting complex subunit 11 RING-H2 f
     0.0012   18.6   2.7     0.0021   17.9   2.7    1.4  1  Prok-RING_4   Prokaryotic RING finger family 4
  ------ inclusion threshold ------
      0.026   14.7   2.3      0.063   13.4   2.3    1.7  1  zf-C3HC4_4    zinc finger of C3HC4-type, RING
      0.051   13.8   2.8       0.13   12.4   2.8    1.7  1  FANCL_C       FANCL C-terminal domain
      0.054   13.1   3.1        0.1   12.2   3.1    1.4  1  Zn_ribbon_17  Zinc-ribbon, C4HC2 type
       0.37   10.9   4.4       0.69   10.1   4.4    1.5  1  RINGv         RING-variant domain
       0.37   10.6   3.2       0.71    9.7   3.2    1.4  1  zf-RING_4     RING/Ubox like zinc-binding domain
       0.39   10.7   3.2        0.7    9.8   3.2    1.5  1  PHD           PHD-finger
        2.1    8.7   3.9        3.8    7.9   3.9    1.4  1  zf-RING-like  RING-like domain


Domain annotation for each model (and alignments):
>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.4   5.5   8.6e-16   8.6e-13       2      44 .]     711     755 ..     710     755 .. 0.90

  Alignments for each domain:
  == domain 1  score: 48.4 bits;  conditional E-value: 8.6e-16
   zf-RING_2   2 eCpICleelssads.vlllpCgHvfhreClerwlrssst.CPlCr 44 
                 eC++Clee+ +++s v+ lpCgH fh eC++ wl+++++ CP+C+
  EEA20668.1 711 ECVVCLEEYVDGQSqVMSLPCGHEFHAECITPWLTTRRRtCPICK 755
                 8********8888757788**************9999999****7 PP

>> zf-RING_11  RING-like zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.5   2.7   6.1e-12   6.1e-09       1      29 []     711     740 ..     711     740 .. 0.96
   2 ?   -1.7   0.1       2.5   2.5e+03       2      12 ..     751     761 ..     751     765 .. 0.78

  Alignments for each domain:
  == domain 1  score: 35.5 bits;  conditional E-value: 6.1e-12
  zf-RING_11   1 eCsICLeefkpgq.alfilpCsHtFHfkCI 29 
                 eC++CLee+ +gq  ++ lpC+H FH +CI
  EEA20668.1 711 ECVVCLEEYVDGQsQVMSLPCGHEFHAECI 740
                 9************888999**********9 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 2.5
  zf-RING_11   2 CsICLeefkpg 12 
                 C IC  ++ ++
  EEA20668.1 751 CPICKGDVVRS 761
                 9***9888765 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.9   4.9     1e-11     1e-08       1      40 []     711     754 ..     711     754 .. 0.87

  Alignments for each domain:
  == domain 1  score: 34.9 bits;  conditional E-value: 1e-11
  zf-C3HC4_2   1 kCpiCldmlkdp...svvtpCgHvfCqkCilrsLeekn.eCPlC 40 
                 +C +Cl+++ d+   +++ pCgH f+++Ci ++L+     CP+C
  EEA20668.1 711 ECVVCLEEYVDGqsqVMSLPCGHEFHAECITPWLTTRRrTCPIC 754
                 6********9983324555****************9999***** PP

>> PA  PA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.2   0.0   1.9e-11   1.9e-08      18      87 ..     211     286 ..     193     288 .. 0.80

  Alignments for each domain:
  == domain 1  score: 34.2 bits;  conditional E-value: 1.9e-11
          PA  18 dfe....gvdvkGkivLvqr...tfaeKarnAqaaGAagviivndgelgaatgasgnegepdgitiPavgvsredge 87 
                 d +      +++Gk+vL +r    f eK++ +q+ G++++i+ +d+  g++  +    g++++itiPav+ s++++ 
  EEA20668.1 211 DIQslqeSAEIAGKVVLLSRggcGFLEKVKWVQRRGGVALIVGDDTR-GGSLITMYARGDTSNITIPAVFTSYTTAH 286
                 44455566799*******9999999******************8776.455555556667778**********9986 PP

>> zf-rbx1  RING-H2 zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.3   3.0   2.1e-11   2.1e-08      16      55 .]     714     755 ..     706     755 .. 0.73

  Alignments for each domain:
  == domain 1  score: 34.3 bits;  conditional E-value: 2.1e-11
     zf-rbx1  16 eckapgdee.cpvvlGeCgHaFHlhCiskWlkt.rkvCPlcr 55 
                  c ++  +   +v+   CgH+FH +Ci+ Wl+t r++CP+c+
  EEA20668.1 714 VCLEEYVDGqSQVMSLPCGHEFHAECITPWLTTrRRTCPICK 755
                 44444433323555559***************98889****6 PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.6   3.9   2.7e-11   2.7e-08       1      41 []     712     754 ..     712     754 .. 0.97

  Alignments for each domain:
  == domain 1  score: 33.6 bits;  conditional E-value: 2.7e-11
                 -TTT-S--SS-E....E-TTS--B-CHHHHHHHHCTSSB--TTT CS
    zf-C3HC4   1 CpiCleeakepn...elleCkHsfCskCirkilksrkkvkCPlC 41 
                 C +Clee+++ +   ++l+C+H+f+ +Ci+ +l   + ++CP+C
  EEA20668.1 712 CVVCLEEYVDGQsqvMSLPCGHEFHAECITPWLT-TRRRTCPIC 754
                 9*********99999*******************.89999**** PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.6   3.1   2.4e-10   2.4e-07       1      43 [.     711     755 ..     711     756 .. 0.97

  Alignments for each domain:
  == domain 1  score: 30.6 bits;  conditional E-value: 2.4e-10
   zf-RING_5   1 hCnkCfekl.skeekfyltsCgHifCekClkkll.ekeavCpiCr 43 
                 +C +C e++  ++++++ ++CgH f+ +C++  l +++++CpiC+
  EEA20668.1 711 ECVVCLEEYvDGQSQVMSLPCGHEFHAECITPWLtTRRRTCPICK 755
                 6********99999******************999*********8 PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.3   3.1   4.9e-09   4.9e-06       2      47 ..     709     758 ..     708     761 .. 0.90

  Alignments for each domain:
  == domain 1  score: 26.3 bits;  conditional E-value: 4.9e-09
                 GSB-TTTSSS....BS-EEETTEEEEEE-HHHHHHHHH.TT-B-TTT--B- CS
  zf-C3HC4_3   2 deeCviCler....prnvvllpCgHlvlCeeCaekllk.rkkkCpiCrrpi 47 
                 + eCv+Cle+    +++v+ lpCgH  +  eC + +l  r+++CpiC+ ++
  EEA20668.1 709 QVECVVCLEEyvdgQSQVMSLPCGHE-FHAECITPWLTtRRRTCPICKGDV 758
                 679******87777999*********.9********999********9876 PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.3   0.5   1.2e-08   1.2e-05       1      39 []     712     752 ..     712     752 .. 0.74
   2 ?    1.1   0.2      0.41   4.1e+02       1       6 [.     751     756 ..     751     768 .. 0.82

  Alignments for each domain:
  == domain 1  score: 25.3 bits;  conditional E-value: 1.2e-08
  zf-RING_UBOX   1 CpIClelft....dPlv.lpCGHtFCreCl..welskslegafkCP 39 
                   C +Cle++     + ++ lpCGH F+ eC+  w       ++++CP
    EEA20668.1 712 CVVCLEEYVdgqsQ-VMsLPCGHEFHAECItpW----LTTRRRTCP 752
                   99******966432.4548***********444....666666776 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.41
  zf-RING_UBOX   1 CpICle 6  
                   CpIC+ 
    EEA20668.1 751 CPICKG 756
                   ****95 PP

>> zf-ANAPC11  Anaphase-promoting complex subunit 11 RING-H2 finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   1.0     2e-06     0.002      45      79 ..     724     756 ..     701     761 .. 0.76

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 2e-06
                 S-EEEBTTS-EEEHHHHHHHHHHHSTSSB-TTTSS CS
  zf-ANAPC11  45 cplvlGkckhnfhlhcilkwletetskglcpmcrq 79 
                   ++   c h fh+ ci+ wl t+  +  cp+c+ 
  EEA20668.1 724 SQVMSLPCGHEFHAECITPWLTTR--RRTCPICKG 756
                 3344445**************875..789****86 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   2.7   2.1e-06    0.0021       1      40 [.     712     758 ..     712     764 .. 0.86

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 2.1e-06
  Prok-RING_4   1 CvlCgeq....ekkailepCgHlvCkeCfdskdls...sCPlCqrri 40 
                  Cv+C e+    +++++  pCgH +  eC   +  +   +CP+C+  +
   EEA20668.1 712 CVVCLEEyvdgQSQVMSLPCGHEFHAECITPWLTTrrrTCPICKGDV 758
                  ******999988889999************99555567*****9765 PP

>> zf-C3HC4_4  zinc finger of C3HC4-type, RING
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   2.3   6.3e-05     0.063      10      42 .]     725     754 ..     712     754 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 6.3e-05
  zf-C3HC4_4  10 kPvsleCGhsfClsCisslqkepdgeqllCplC 42 
                 + +sl+CGh f  +Ci+ +         +Cp C
  EEA20668.1 725 QVMSLPCGHEFHAECITPWLTTRRR---TCPIC 754
                 559****************999976...59999 PP

>> FANCL_C  FANCL C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   2.8   0.00013      0.13       2      46 ..     709     749 ..     708     763 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00013
                 --S-SSS--SS-TT-----B--S-TT----B-SGGGHHHHHHHHS CS
     FANCL_C   2 eveCgiCyayrldsgevpdisCdnekCnkkfHsaCLkeWlrslke 46 
                 +veC +C+ + + +g+  ++s     C+++fH++C++ Wl + + 
  EEA20668.1 709 QVECVVCLEEYV-DGQSQVMS---LPCGHEFHAECITPWLTTRRR 749
                 789999999999.56655554...67**************98775 PP

>> Zn_ribbon_17  Zinc-ribbon, C4HC2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   3.1    0.0001       0.1       5      47 ..     710     753 ..     707     760 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.0001
  Zn_ribbon_17   5 ksCayC.elavkgrv.vlcgvCeHvlHasCarewfenddlaeCps 47 
                    +C++C e  v g+  v+   C+H  Ha+C+  w+++     Cp 
    EEA20668.1 710 VECVVClEEYVDGQSqVMSLPCGHEFHAECITPWLTTRR-RTCPI 753
                   679999434566654267889***************999.99985 PP

>> RINGv  RING-variant domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   4.4    0.0007      0.69       1      48 []     712     754 ..     712     754 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.0007
                 ETTTTEE-SSSS..--B-SS--STCCCSB-HHHHHHHHHHTCT-SB-TTT CS
       RINGv   1 CriCleeeeese..plispCkCrGslklvHesClekWldekeantqCeiC 48 
                 C +Clee  + +   +  pC   G  + +H +C+  Wl++  + ++C iC
  EEA20668.1 712 CVVCLEEYVDGQsqVMSLPC---G--HEFHAECITPWLTT--RRRTCPIC 754
                 77777776666632444444...3..679**********9..9999**** PP

>> zf-RING_4  RING/Ubox like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   3.2   0.00072      0.71       1      44 [.     712     755 ..     712     757 .. 0.90

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00072
   zf-RING_4   1 cplCdeeldetdkdlkpCeCgyqiClfCyhrileeeegrCPaCr 44 
                 c +C ee  +  ++++  +Cg+++   C +  l++    CP C+
  EEA20668.1 712 CVVCLEEYVDGQSQVMSLPCGHEFHAECITPWLTTRRRTCPICK 755
                 889999997777888888*************************9 PP

>> PHD  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   3.2   0.00071       0.7       2      50 ..     712     755 ..     711     757 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00071
                 BTTTTSTTSTTSCEEEETTTSCEEETTTSSSTHSHHSHHSSTBSSTTTH CS
         PHD   2 CavCkkksdeeeelvqCdgCkrwfHqkClkppleseekpegewlCekCk 50 
                 C vC ++  +++  v+   C++ fH +C++p l+++++     +C+ Ck
  EEA20668.1 712 CVVCLEEYVDGQSQVMSLPCGHEFHAECITPWLTTRRR-----TCPICK 755
                 9*****88889999999***************995544.....688887 PP

>> zf-RING-like  RING-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   3.9    0.0039       3.8      17      43 .]     729     754 ..     712     754 .. 0.77

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0039
  zf-RING-like  17 esCnvrlHvdCfqhyirthsskkCpkC 43 
                     C   +H +C++  + t ++++Cp C
    EEA20668.1 729 LPCGHEFHAECITPWL-TTRRRTCPIC 754
                   5699************.77777***99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (829 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1037  (0.0578393); expected 358.6 (0.02)
Passed bias filter:                      615  (0.034302); expected 358.6 (0.02)
Passed Vit filter:                        75  (0.00418317); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              18  [number of targets reported over threshold]
# CPU time: 0.75u 0.29s 00:00:01.04 Elapsed: 00:00:00.47
# Mc/sec: 5339.64
//
Query:       EEA20669.1  [L=439]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        9.9    6.0  17.4         11    5.8   0.0    5.5  6  YpzI      YpzI-like protein


Domain annotation for each model (and alignments):
>> YpzI  YpzI-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0    0.0023        41      14      23 ..      39      48 ..      36      61 .. 0.78
   2 ?    3.0   0.3    0.0048        86      13      21 ..     193     201 ..     189     203 .. 0.85
   3 ?    5.8   0.0   0.00063        11      14      30 ..     254     270 ..     250     274 .. 0.84
   4 ?   -1.0   0.4     0.084   1.5e+03      14      20 ..     319     325 ..     316     327 .. 0.82
   5 ?    0.9   0.0     0.022     4e+02      13      30 ..     367     386 ..     365     388 .. 0.73
   6 ?   -2.3   0.2      0.22   3.9e+03      14      22 ..     420     428 ..     417     430 .. 0.79

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.0023
        YpzI 14 krvESDRDQs 23
                 rv SDRD  
  EEA20669.1 39 PRVDSDRDGR 48
                69******65 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.0048
        YpzI  13 skrvESDRD 21 
                   rv SDRD
  EEA20669.1 193 DPRVDSDRD 201
                 67******9 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.00063
        YpzI  14 krvESDRDQslsykGAt 30 
                  rv SDRD    + G t
  EEA20669.1 254 PRVDSDRDHRATHGGMT 270
                 69******988888876 PP

  == domain 4  score: -1.0 bits;  conditional E-value: 0.084
        YpzI  14 krvESDR 20 
                  rv SDR
  EEA20669.1 319 PRVDSDR 325
                 69****9 PP

  == domain 5  score: 0.9 bits;  conditional E-value: 0.022
        YpzI  13 skrvESDRDQslsyk..GAt 30 
                   rv SD D    y+  GAt
  EEA20669.1 367 DPRVDSDMDNRARYQnmGAT 386
                 569******98777534776 PP

  == domain 6  score: -2.3 bits;  conditional E-value: 0.22
        YpzI  14 krvESDRDQ 22 
                  rv SD D 
  EEA20669.1 420 PRVDSDLDG 428
                 59****886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (439 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       433  (0.0241508); expected 358.6 (0.02)
Passed bias filter:                      143  (0.0079759); expected 358.6 (0.02)
Passed Vit filter:                         9  (0.00050198); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.25s 00:00:00.72 Elapsed: 00:00:00.43
# Mc/sec: 3083.48
//
Query:       EEA20670.1  [L=340]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        5.9    6.7  12.6        8.1    6.3   0.0    4.7  5  YpzI      YpzI-like protein


Domain annotation for each model (and alignments):
>> YpzI  YpzI-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.3    0.0036        64      13      21 ..      94     102 ..      90     104 .. 0.85
   2 ?    6.3   0.0   0.00045       8.1      14      30 ..     155     171 ..     151     176 .. 0.84
   3 ?   -0.2   0.1     0.048   8.7e+02      14      20 ..     220     226 ..     216     229 .. 0.83
   4 ?    1.4   0.0     0.015   2.7e+02      13      30 ..     268     287 ..     265     289 .. 0.74
   5 ?   -1.9   0.2      0.16   2.9e+03      14      22 ..     321     329 ..     318     331 .. 0.79

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.0036
        YpzI  13 skrvESDRD 21 
                   rv SDRD
  EEA20670.1  94 DPRVDSDRD 102
                 67******9 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.00045
        YpzI  14 krvESDRDQslsykGAt 30 
                  rv SDRD    + G t
  EEA20670.1 155 PRVDSDRDHRATHGGMT 171
                 69******988888876 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 0.048
        YpzI  14 krvESDR 20 
                  rv SDR
  EEA20670.1 220 PRVDSDR 226
                 69****9 PP

  == domain 4  score: 1.4 bits;  conditional E-value: 0.015
        YpzI  13 skrvESDRDQslsyk..GAt 30 
                   rv SD D    y+  GAt
  EEA20670.1 268 DPRVDSDMDNRARYQnmGAT 287
                 579******98777534776 PP

  == domain 5  score: -1.9 bits;  conditional E-value: 0.16
        YpzI  14 krvESDRDQ 22 
                  rv SD D 
  EEA20670.1 321 PRVDSDLDG 329
                 59****886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (340 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       407  (0.0227007); expected 358.6 (0.02)
Passed bias filter:                      132  (0.00736237); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 2355.34
//
Query:       EEA20671.1  [L=709]
Description: hypothetical protein PMAA_044970 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (709 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       629  (0.0350828); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.66u 0.29s 00:00:00.95 Elapsed: 00:00:00.47
# Mc/sec: 4513.48
//
Query:       EEA20672.1  [L=548]
Description: benzoate 4-monooxygenase cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-63  215.2   0.0    2.6e-63  214.4   0.0    1.3  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  214.4   0.0   1.4e-67   2.6e-63       3     443 ..      95     518 ..      93     535 .. 0.85

  Alignments for each domain:
  == domain 1  score: 214.4 bits;  conditional E-value: 1.4e-67
                 SES.EHHCCHCHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHHH CS
        p450   3 gpt.plplvgnllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkklRr 100
                 +++ ++  ++  +q++ +++ h  + ++++kyg+i+r+   s +  ++ +p+av++v ++  + +  + +++ ++     + +++  f++     k Rr
  EEA20672.1  95 PFSaRISSLWLCFQVSPQKQAHLTMLDIHQKYGKIVRVG--SNDLSIV-HPKAVEKVHNTCLKGPFYDLNNPDTSV----QSTRDKTFHD-----KCRR 181
                 55558888999************************9975..5555444.59******9999655555555555553....5555555555.....99** PP

                 HHHHHHTSHSTT.THHHHHHHHHHHHHHHHHCCCCHCS....EEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCC CS
        p450 101 fltptltsfgkl.sleelveeeaedlveklrkkagess....elditellskaaldvigsilFgarfdlledeklselvkaveelssllskssvqllll 194
                    +++t++  l  +e++++++ + l+++++++++ ++     ++ t+l++++a+dv+g+++Fg++fd+l+++k+ e+v++ +e + +l + ++ ++l+
  EEA20672.1 182 PWSMAFTDN-RLrDYEPRIKKIHKHLLARIDQDSKNNEndgkPVNATRLINHYAFDVMGEVAFGSHFDMLNTSKSHEAVEMLNESMGMLGF-MCPIWLV 278
                 *********.888********************99999999********************************************999955.4455555 PP

                 CH.HHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS CS
        p450 195 fp.llkylptkllrklkeavkklkdlldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLakn 292
                    ++  +p+ +++ +   v++ ++ ++++    r t  s+       ++ +l +  ek++++ + ++ l+ ++  + +aG+dTts++l+ aLyeL++n
  EEA20672.1 279 RFaVA--IPGLTRKWWI-FVEYCFQQMEMC----RLTKPSS-----PVIASTLVKPYEKREPTPFEKRVLRGEAQLIVVAGSDTTSAALTCALYELVRN 365
                 44144..4554444444.334444444444....4333333.....455555555533344479*********************************** PP

                 HHHHHHHHHHHHHHC.CTTTT-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS.CEEETT.EEE-TT-EEEEEHHHHHT-TTTSSSTTS--GGGG CS
        p450 293 PevqeklreEidevl.gdkreptyddlqklpyldavikEtLRlhpvvplllpRevtk.dvvirg.ylipkGtevivnlyalhrdpevfpnPeeFdpeRF 388
                 P+++++lre i   l ++ + ++  ++ +l  l+ +i+EtLRl+p+vp++l R ++   + i++   ip + +v+++ y l+r+++++++P+ F peR+
  EEA20672.1 366 PHITNQLREAISASLsPNEKDISAHHVRNLDILNGIINETLRLYPPVPTTLWRLTPPgGLWIDEeTYIPGNVTVSTPQYVLGRSNDLYERPNDFIPERW 464
                 ***************99999*********************************999879999999********************************** PP

                 B-TTSCTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSG CS
        p450 389 ldekgnskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdp 443
                  ++ +   +++ af PF+ Gp +C+G++lA+m+l++ la+l+ +++++l+p  ++
  EEA20672.1 465 YSRPE-MIKQEKAFAPFSVGPFSCVGRPLAMMNLRMTLAQLIYTYDISLPPSMTM 518
                 ***99.559***************************************9886554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (548 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       494  (0.0275531); expected 358.6 (0.02)
Passed bias filter:                      416  (0.0232026); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.36s 00:00:00.93 Elapsed: 00:00:00.48
# Mc/sec: 3443.28
//
Query:       EEA20673.1  [L=1437]
Description: TORC1 growth control complex subunit Kog1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.4e-66  220.8   0.0    1.2e-65  220.0   0.0    1.5  1  Raptor_N         Raptor N-terminal CASPase like domain
    7.9e-07   29.7  10.9        0.4   11.6   0.0    6.6  6  WD40             WD domain, G-beta repeat
     0.0086   16.2   2.2        1.5    9.3   0.0    3.5  3  HEAT             HEAT repeat
  ------ inclusion threshold ------
      0.016   15.2   2.5        1.3    9.1   0.3    2.9  3  BBS2_Mid         Ciliary BBSome complex subunit 2, middle reg
       0.15   12.1   0.1       0.31   11.1   0.1    1.5  1  Atx10homo_assoc  Spinocerebellar ataxia type 10 protein domai


Domain annotation for each model (and alignments):
>> Raptor_N  Raptor N-terminal CASPase like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  220.0   0.0   3.3e-69   1.2e-65       1     147 []     194     347 ..     194     347 .. 0.97

  Alignments for each domain:
  == domain 1  score: 220.0 bits;  conditional E-value: 3.3e-69
    Raptor_N   1 lktksvilvlclnigvdppdvvktkpcarleawidpss.e......leeiaknlqdqyeslqlrarykqlldptvedvkklcqslrrnakdervlfHYn 92 
                 lkt+s++l +clnigvdppdvvkt+p a+le+w+dp+s +      +e+i+k+lq+qye+l+lr+rykq+ldp+v+++kk+c slrrnakdervlfHYn
  EEA20673.1 194 LKTVSAALAICLNIGVDPPDVVKTNPSAKLECWVDPTStTggqnkmMEQIGKKLQEQYENLSLRTRYKQYLDPSVDETKKFCISLRRNAKDERVLFHYN 292
                 59************************************536778877**************************************************** PP

    Raptor_N  93 GhgvprptengeiwvfdksytqyiplslaelqewlgspsiyifDCsnAglileaf 147
                 Ghgvp pt++geiwvf+k+ytqyip+sl++lq+wl +ps+++fD s+Ag+i+++f
  EEA20673.1 293 GHGVPLPTQSGEIWVFNKNYTQYIPVSLYDLQSWLAGPSLFVFDVSHAGNIIHNF 347
                 ****************************************************998 PP

>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.1      0.13   4.5e+02      16      38 .]    1132    1154 ..    1117    1154 .. 0.88
   2 !    6.6   0.0    0.0045        16      12      37 ..    1172    1200 ..    1158    1201 .. 0.71
   3 ?    3.3   0.1     0.048   1.7e+02      13      38 .]    1272    1298 ..    1260    1298 .. 0.69
   4 !   11.6   0.0   0.00011       0.4       5      38 .]    1309    1344 ..    1306    1344 .. 0.78
   5 ?   -1.3   0.0       1.3   4.8e+03       3      26 ..    1360    1393 ..    1358    1400 .. 0.71
   6 !    6.6   0.6    0.0043        16       6      35 ..    1400    1433 ..    1395    1435 .. 0.75

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.13
                  EEEETTSSEEEEEETTSEEEEEE CS
        WD40   16 lafspdgawlasGsdDgtvriWd 38  
                  ++f++  + la G+d  t+ iWd
  EEA20673.1 1132 MSFHQFEDHLAVGDDRDTISIWD 1154
                  568889999****99*******9 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0045
                  S.EEEEE..EETTSSEEEEEETTSEEEEE CS
        WD40   12 s.vtsla..fspdgawlasGsdDgtvriW 37  
                  s ++ ++  + +d+a+l++Gs Dg ++++
  EEA20673.1 1172 SkINEIRyiNEDDQALLMTGSSDGVLKVY 1200
                  2567666768889999****99*****98 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.048
                  EEEEE.EETTSSEEEEE.ETTSEEEEEE CS
        WD40   13 vtsla.fspdgawlasG.sdDgtvriWd 38  
                  +tsl   +  g+ +++G + Dg +r++d
  EEA20673.1 1272 ITSLTsDQVAGNIFIAGfG-DGAIRVFD 1298
                  5666443334455678955.******98 PP

  == domain 4  score: 11.6 bits;  conditional E-value: 0.00011
                  EEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS
        WD40    5 rtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38  
                  ++++ H +++t +  ++ g   l+sGs++g +r+Wd
  EEA20673.1 1309 KVWREHkQWITNVHMQRGGVReLVSGSRNGEIRLWD 1344
                  678889777999954444444999***********9 PP

  == domain 5  score: -1.3 bits;  conditional E-value: 1.3
                  EEEEEESS..SSEEEEE........EETTSSEEE CS
        WD40    3 clrtltGH..ssvtsla........fspdgawla 26  
                  +lrtl+ H   +v  +         f+ dg++l+
  EEA20673.1 1360 TLRTLSVHehAPVFTVGtnrhevktFNVDGTYLS 1393
                  6889998854557766666666778888888875 PP

  == domain 6  score: 6.6 bits;  conditional E-value: 0.0043
                  EEESS..SS.EEEEEEETTSSEEEEEE.TTSEEE CS
        WD40    6 tltGH..ss.vtslafspdgawlasGs.dDgtvr 35  
                  ++  H  ss +++ af+p+ ++la+++  D+++ 
  EEA20673.1 1400 SFLHHnrSSpISATAFHPHRTLLACSGlQDNHIN 1433
                  5556766335*************96665799996 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       4.9   1.7e+04      14      30 ..     672     688 ..     671     689 .. 0.82
   2 ?    4.7   0.2     0.012        44       2      27 ..     702     728 ..     701     729 .. 0.86
   3 !    9.3   0.0   0.00041       1.5       5      27 ..     748     770 ..     745     773 .. 0.90

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 4.9
                 HHHHHHHHHHHHHHHHC CS
        HEAT  14 peVReaAakaLgalaev 30 
                 +e R+++a  +  ++++
  EEA20673.1 672 SEHRAMCAFIVSIFCKN 688
                 57899999999999886 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.012
                 HHHHHHHHT-.SSHHHHHHHHHHHHHH CS
        HEAT   2 lPlllkllsD.pspeVReaAakaLgal 27 
                 ++ +l+ l+D ++p  R+ ++++L  l
  EEA20673.1 702 FDSCLNHLMDvENPLLRQWSCLCLSML 728
                 56789999999*************866 PP

  == domain 3  score: 9.3 bits;  conditional E-value: 0.00041
                 HHHHHT-SSHHHHHHHHHHHHHH CS
        HEAT   5 llkllsDpspeVReaAakaLgal 27 
                 l++l  Dp peVR+a + aL+++
  EEA20673.1 748 LCELSLDPVPEVRAAMLHALTNF 770
                 899999**************987 PP

>> BBS2_Mid  Ciliary BBSome complex subunit 2, middle region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.1       2.5   8.9e+03      68      82 ..    1088    1102 ..    1086    1105 .. 0.83
   2 ?    5.0   0.0    0.0068        24       7      51 ..    1180    1224 ..    1177    1231 .. 0.84
   3 ?    9.1   0.3   0.00035       1.3      10     106 ..    1236    1341 ..    1228    1343 .. 0.61

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 2.5
    BBS2_Mid   68 kerlWrvksknevva 82  
                  +erlWr + +++++a
  EEA20673.1 1088 NERLWRRSRNERIIA 1102
                  78****999999876 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.0068
    BBS2_Mid    7 vdgdgeneLvvgsddfeirvfkeeelvaeitetekvvslarleke 51  
                  +++d+++ L+ gs d  ++v+++ e  ++i++  +  +l +l ++
  EEA20673.1 1180 INEDDQALLMTGSSDGVLKVYRNYETRKKIEIVTAFRALPELIPS 1224
                  567889999******************999999888888777665 PP

  == domain 3  score: 9.1 bits;  conditional E-value: 0.00035
    BBS2_Mid   10 dgeneLvvgsddfeirvfkee.elvae.i..tetekvvsla..rlekerfayaleNGtvgvyekker.......lWrvksknevvalaaydingdgt 93  
                  +g+ + +v+ d   irv++   e+ ++ i  +  + ++sl+  ++ ++ f++++  G + v++++ +       +Wr   k+    ++++ ++  g+
  EEA20673.1 1236 QGQGKALVAGDVKVIRVWNAAtEVCTNdIsaRSGSCITSLTsdQVAGNIFIAGFGDGAIRVFDQRLKstaamvkVWREH-KQ---WITNVHMQRGGV 1328
                  3566667777888899998762333331310333445666533466666**************9765111111145532.33...344555667799 PP

    BBS2_Mid   94 kelivgwsnGkld 106 
                  +el+ g +nG++ 
  EEA20673.1 1329 RELVSGSRNGEIR 1341
                  **********986 PP

>> Atx10homo_assoc  Spinocerebellar ataxia type 10 protein domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.1   8.8e-05      0.31       5      57 ..     678     729 ..     674     738 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 8.8e-05
  Atx10homo_assoc   5 lvrllgnlvyknkevqdkvreldgleliLsqcniDdnnPfirewailairnLl 57 
                      +  +++  + + ++ q+ + + + +  +L++  +D +nP++r+w+ l++  L 
       EEA20673.1 678 CAFIVSIFCKNYPQGQNVCLSAELFDSCLNHL-MDVENPLLRQWSCLCLSMLW 729
                      55678888999999999999999999999986.8***************9886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1437 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       437  (0.0243739); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.86u 0.31s 00:00:01.17 Elapsed: 00:00:00.49
# Mc/sec: 8828.51
//
Query:       EEA20674.1  [L=1515]
Description: cell polarity protein (Tea1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.5e-32  109.3  11.8    1.5e-08   34.5   0.7    6.6  6  Kelch_4       Galactose oxidase, central domain
    5.4e-31  106.3  16.1    3.2e-07   30.5   0.2    6.8  6  Kelch_3       Galactose oxidase, central domain
    6.2e-30  102.5   0.6    2.1e-12   46.4   0.1    6.0  6  Kelch_1       Kelch motif
    6.4e-30  102.4   7.9    4.2e-12   45.9   0.7    6.2  6  Kelch_6       Kelch motif
    4.9e-26   90.2   8.5    5.1e-07   29.5   0.1    6.8  6  Kelch_5       Kelch motif
    1.4e-20   72.4  10.6      1e-10   41.2   0.6    6.6  6  Kelch_2       Kelch motif
     0.0031   16.5  21.4     0.0031   16.5  21.4    5.1  5  Spc7          Spc7 kinetochore protein
     0.0036   17.4  20.7     0.0036   17.4  20.7    7.2  8  TPR_MLP1_2    TPR/MLP1/MLP2-like protein


Domain annotation for each model (and alignments):
>> Kelch_4  Galactose oxidase, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.8   0.0   0.00071       1.6       1      32 [.     129     162 ..     129     163 .. 0.90
   2 !   21.8   0.1   6.3e-08   0.00014       1      48 [.     185     235 ..     185     237 .. 0.84
   3 !   22.0   0.1   5.5e-08   0.00012       1      42 [.     239     283 ..     239     297 .. 0.88
   4 !   34.5   0.7   6.5e-12   1.5e-08       1      44 [.     302     343 ..     302     351 .. 0.92
   5 !   18.3   0.0   7.8e-07    0.0017       1      48 [.     352     401 ..     352     402 .. 0.86
   6 !    5.8   0.0    0.0063        14       1      23 [.     403     424 ..     403     443 .. 0.73

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00071
     Kelch_4   1 pRaghsatsi..pdgtiylfGGrgedgtllndly 32 
                 pR g+++ si    g+iy+ GG  +  t+ +dl+
  EEA20674.1 129 PRYGAAINSIasKEGDIYMMGGLIDGSTVKGDLW 162
                 899*******6555***********99*999999 PP

  == domain 2  score: 21.8 bits;  conditional E-value: 6.3e-08
     Kelch_4   1 pRaghsatsipdgtiylfGGrgedg..tllndl.ylldlstntWrrl.gslP 48 
                 pR+gh++  ++ + +++fGG +  +   +l+d+ yll++s+++W+r  ++ P
  EEA20674.1 185 PRVGHASLLVG-NAFIVFGGDTKVNdnDVLDDTlYLLNTSSRQWSRAiPPGP 235
                 9*********7.67777***86544458*****************9987666 PP

  == domain 3  score: 22.0 bits;  conditional E-value: 5.5e-08
     Kelch_4   1 pRaghsatsipdgtiylfGGrgedgtllndlylldl.....stntWr 42 
                 +R gh++  ++  ++y+fGG+ + g ++ndl ++dl     +tn+W+
  EEA20674.1 239 GRYGHTLNILG-SRLYVFGGQVD-GFFFNDLIAFDLnalqsPTNKWE 283
                 599*******7.7**********.6***********99999999996 PP

  == domain 4  score: 34.5 bits;  conditional E-value: 6.5e-12
     Kelch_4   1 pRaghsatsipdgtiylfGGrgedgtllndlylldlstntWrrl 44 
                 pR +h+++s  ++++ylfGG ++    +nd++ +d  tn+W++l
  EEA20674.1 302 PRTNHTTISH-NDKLYLFGGTNGS-LWFNDVWCYDPRTNSWSEL 343
                 9*********.7***********9.7***************987 PP

  == domain 5  score: 18.3 bits;  conditional E-value: 7.8e-07
     Kelch_4   1 pRaghsatsipdgtiylfGGrgedgtllndlylldlstntW...rrlgslP 48 
                 pR gh+a  i+ +t y+fGGr+edg  l+dl ++ + +++W     +g++P
  EEA20674.1 352 PREGHAAALIG-DTMYVFGGRNEDGIDLGDLSAFRIGNKRWfsfHNMGPAP 401
                 7889******6.9***********************999996665556666 PP

  == domain 6  score: 5.8 bits;  conditional E-value: 0.0063
     Kelch_4   1 pRaghsatsipdgtiylfGGrge 23 
                 pR ghs+t+ ++  i++  G+ +
  EEA20674.1 403 PRSGHSMTAFGR-QIIVLAGEPS 424
                 9*********85.5555666655 PP

>> Kelch_3  Galactose oxidase, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.0   0.00018       0.4       4      47 ..     145     192 ..     142     194 .. 0.83
   2 !   17.4   0.1   1.8e-06     0.004       1      46 [.     195     245 ..     195     247 .. 0.87
   3 !   25.7   0.0   4.4e-09     1e-05       1      46 [.     249     308 ..     249     311 .. 0.82
   4 !   30.5   0.2   1.4e-10   3.2e-07       1      49 []     312     361 ..     312     361 .. 0.95
   5 !   28.2   0.1   7.2e-10   1.6e-06       1      49 []     362     412 ..     362     412 .. 0.91
   6 ?   -2.2   0.2       2.5   5.5e+03      35      47 ..     536     548 ..     522     549 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00018
     Kelch_3   4 lyifGGlgddgqdrlndvyvydldtntWa.....eiaslppaRaghaat 47 
                 +y  GGl  dg ++ +d++++  + ++       ++++ p++R+gha+ 
  EEA20674.1 145 IYMMGGLI-DGSTVKGDLWMVESSGGNLScfpipTVSEGPGPRVGHASL 192
                 77777777.8***********999998888866566999*******985 PP

  == domain 2  score: 17.4 bits;  conditional E-value: 1.8e-06
     Kelch_3   1 gdrlyifGGlgd..dgqdrlndvyvydldtntWaei...aslppaRaghaa 46 
                 g+ + +fGG +   d+   + ++y++++++ +W +    ++ p +R+gh++
  EEA20674.1 195 GNAFIVFGGDTKvnDNDVLDDTLYLLNTSSRQWSRAippGPRPAGRYGHTL 245
                 78999******9877677779999**********8877788899*****97 PP

  == domain 3  score: 25.7 bits;  conditional E-value: 4.4e-09
     Kelch_3   1 gdrlyifGGlgddgqdrlndvyvydl.....dtntWa....ei.......aslppaRaghaa 46 
                 g rly+fGG     + + nd+ ++dl      tn+W+    ++       ++ pp+R++h++
  EEA20674.1 249 GSRLYVFGGQV--DGFFFNDLIAFDLnalqsPTNKWEflirNTseggppaGQIPPPRTNHTT 308
                 679********..59***********66666556***9887335777778999*******97 PP

  == domain 4  score: 30.5 bits;  conditional E-value: 1.4e-10
     Kelch_3   1 gdrlyifGGlgddgqdrlndvyvydldtntWaei...aslppaRaghaatai 49 
                 +d+ly+fGG +  g    ndv+ yd+ tn+W e+   +  p++R ghaa++i
  EEA20674.1 312 NDKLYLFGGTN--GSLWFNDVWCYDPRTNSWSELdciGFVPSPREGHAAALI 361
                 799********..*********************998999********9976 PP

  == domain 5  score: 28.2 bits;  conditional E-value: 7.2e-10
     Kelch_3   1 gdrlyifGGlgddgqdrlndvyvydldtntWa...eiaslppaRaghaatai 49 
                 gd++y+fGG++ d +  l+d+ ++ +++  W    + ++ p++R+gh++ta+
  EEA20674.1 362 GDTMYVFGGRNED-GIDLGDLSAFRIGNKRWFsfhNMGPAPSPRSGHSMTAF 412
                 89*********65.999************99966677*************96 PP

  == domain 6  score: -2.2 bits;  conditional E-value: 2.5
     Kelch_3  35 aslppaRaghaat 47 
                 a++p++R++  +t
  EEA20674.1 536 APTPTPRMNGQVT 548
                 67899***97766 PP

>> Kelch_1  Kelch motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       3.3   7.4e+03      11      22 ..     142     153 ..     137     158 .. 0.77
   2 !   10.5   0.0   0.00016      0.36       1      41 [.     185     229 ..     185     231 .. 0.96
   3 !   20.3   0.0   1.4e-07    0.0003       2      41 ..     240     284 ..     239     285 .. 0.96
   4 !   46.4   0.1   9.6e-16   2.1e-12       1      42 [.     302     343 ..     302     344 .. 0.98
   5 !   13.5   0.0   1.8e-05     0.039       1      22 [.     352     373 ..     352     391 .. 0.86
   6 ?    4.4   0.0     0.013        28       1      34 [.     403     441 ..     403     443 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 3.3
                 TTEEEEEEEBCS CS
     Kelch_1  11 ggkiYviGGsdg 22 
                  g iY +GG  +
  EEA20674.1 142 EGDIYMMGGLID 153
                 699******766 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00016
                 BBBSEEEEEETTEEEEEEEBCS....SSBEEEEEEEETTTTEEEE CS
     Kelch_1   1 aragagavvvggkiYviGGsdg....gnalssvevyDpetntWre 41 
                 +r g+++  vg+   v+GG           ++++ +++ + +W++
  EEA20674.1 185 PRVGHASLLVGNAFIVFGGDTKvndnDVLDDTLYLLNTSSRQWSR 229
                 79***********************9999**************98 PP

  == domain 3  score: 20.3 bits;  conditional E-value: 1.4e-07
                 BBSEEEEEETTEEEEEEEBCSSSBEEEEEEEETT.....TTEEEE CS
     Kelch_1   2 ragagavvvggkiYviGGsdggnalssvevyDpe.....tntWre 41 
                 r+g++   +g ++Yv+GG+ +g + +++ ++D+      tn+W+ 
  EEA20674.1 240 RYGHTLNILGSRLYVFGGQVDGFFFNDLIAFDLNalqspTNKWEF 284
                 99*****************************************96 PP

  == domain 4  score: 46.4 bits;  conditional E-value: 9.6e-16
                 BBBSEEEEEETTEEEEEEEBCSSSBEEEEEEEETTTTEEEEE CS
     Kelch_1   1 aragagavvvggkiYviGGsdggnalssvevyDpetntWrel 42 
                 +r++++  ++++k+Y +GG +g+   ++v++yDp+tn+W+el
  EEA20674.1 302 PRTNHTTISHNDKLYLFGGTNGSLWFNDVWCYDPRTNSWSEL 343
                 79**************************************96 PP

  == domain 5  score: 13.5 bits;  conditional E-value: 1.8e-05
                 BBBSEEEEEETTEEEEEEEBCS CS
     Kelch_1   1 aragagavvvggkiYviGGsdg 22 
                 +r g++a+ +g+ +Yv+GG+++
  EEA20674.1 352 PREGHAAALIGDTMYVFGGRNE 373
                 6889****************98 PP

  == domain 6  score: 4.4 bits;  conditional E-value: 0.013
                 BBBSEEEEEETTEEEEEEEBCS.....SSBEEEEEEEET CS
     Kelch_1   1 aragagavvvggkiYviGGsdg.....gnalssvevyDp 34 
                 +r+g++++++g +i v+ G  +     ++ ls ++++D+
  EEA20674.1 403 PRSGHSMTAFGRQIIVLAGEPSsaprdPTELSMAYILDT 441
                 7****************9987777888888888888877 PP

>> Kelch_6  Kelch motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.8   0.0     0.004       8.9       5      31 ..     136     162 ..     133     163 .. 0.86
   2 !    9.1   0.0   0.00072       1.6       1      42 [.     185     229 ..     185     237 .. 0.84
   3 !   21.2   0.0   1.1e-07   0.00026       2      43 ..     240     285 ..     240     288 .. 0.89
   4 !   45.9   0.7   1.9e-15   4.2e-12       1      43 [.     302     343 ..     302     353 .. 0.89
   5 !   18.1   0.0   1.1e-06    0.0025       1      40 [.     352     391 ..     352     404 .. 0.90
   6 ?   -0.2   0.0       0.6   1.3e+03       1      20 [.     403     422 ..     403     442 .. 0.83

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.004
     Kelch_6   5 hslvsvggkiYifGGytdsspylnkvw 31 
                 +s++s  g iY++GG+ d+s+   ++w
  EEA20674.1 136 NSIASKEGDIYMMGGLIDGSTVKGDLW 162
                 799*************99877777776 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.00072
     Kelch_6   1 praghslvsvggkiYifGGytds...spylnkvwvydpetksWeq 42 
                 pr+gh++ +vg+ + +fGG t     +   + +++++ +++ W++
  EEA20674.1 185 PRVGHASLLVGNAFIVFGGDTKVndnDVLDDTLYLLNTSSRQWSR 229
                 699*******************999755557777799*****996 PP

  == domain 3  score: 21.2 bits;  conditional E-value: 1.1e-07
     Kelch_6   2 raghslvsvggkiYifGGytdsspylnkvwvydpe.....tksWeql 43 
                 r+gh+l + g+++Y+fGG++d + ++n+++ +d+      t++We+l
  EEA20674.1 240 RYGHTLNILGSRLYVFGGQVD-GFFFNDLIAFDLNalqspTNKWEFL 285
                 789******************.9**********55555669999975 PP

  == domain 4  score: 45.9 bits;  conditional E-value: 1.9e-15
     Kelch_6   1 praghslvsvggkiYifGGytdsspylnkvwvydpetksWeql 43 
                 pr+ h+++s+++k+Y+fGG ++ s ++n+vw+ydp+t+sW++l
  EEA20674.1 302 PRTNHTTISHNDKLYLFGGTNG-SLWFNDVWCYDPRTNSWSEL 343
                 79********************.89****************96 PP

  == domain 5  score: 18.1 bits;  conditional E-value: 1.1e-06
     Kelch_6   1 praghslvsvggkiYifGGytdsspylnkvwvydpetksW 40 
                 pr gh+++++g++ Y+fGG++ ++  l ++  +++ +k+W
  EEA20674.1 352 PREGHAAALIGDTMYVFGGRNEDGIDLGDLSAFRIGNKRW 391
                 5779***********************************9 PP

  == domain 6  score: -0.2 bits;  conditional E-value: 0.6
     Kelch_6   1 praghslvsvggkiYifGGy 20 
                 pr ghs+++ g +i ++ G 
  EEA20674.1 403 PRSGHSMTAFGRQIIVLAGE 422
                 699************99886 PP

>> Kelch_5  Kelch motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.0   0.00052       1.2       2      35 ..     127     162 ..     127     164 .. 0.74
   2 !    7.8   0.0    0.0015       3.3       2      40 ..     183     223 ..     182     225 .. 0.82
   3 !   22.1   0.1   4.8e-08   0.00011       2      39 ..     237     272 ..     237     274 .. 0.95
   4 !   29.5   0.1   2.3e-10   5.1e-07       1      42 []     299     338 ..     299     338 .. 0.93
   5 !   17.7   0.0   1.2e-06    0.0026       1      27 [.     349     373 ..     349     381 .. 0.89
   6 ?    2.5   0.0     0.069   1.6e+02       2      19 ..     401     418 ..     400     422 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00052
     Kelch_5   2 PppRaghcav.tvs..ekiYvyGGkvgrdgsvs.ddvy 35 
                 P pR+g+++  ++s  + iY++GG +  dgs   +d++
  EEA20674.1 127 PFPRYGAAINsIASkeGDIYMMGGLI--DGSTVkGDLW 162
                 99*******746775677*******9..3433335666 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0015
     Kelch_5   2 PppRaghcavtvsekiYvyGGkvg..rdgsvsddvyvLdlp 40 
                 P pR gh++  v++  +v+GG +    ++ + d +y L++ 
  EEA20674.1 183 PGPRVGHASLLVGNAFIVFGGDTKvnDNDVLDDTLYLLNTS 223
                 99*******************99894455555788898876 PP

  == domain 3  score: 22.1 bits;  conditional E-value: 4.8e-08
     Kelch_5   2 PppRaghcavtvsekiYvyGGkvgrdgsvsddvyvLdl 39 
                 P++R+gh   ++++ +Yv+GG v  dg +++d+  +dl
  EEA20674.1 237 PAGRYGHTLNILGSRLYVFGGQV--DGFFFNDLIAFDL 272
                 999********************..9*******99887 PP

  == domain 4  score: 29.5 bits;  conditional E-value: 2.3e-10
     Kelch_5   1 iPppRaghcavtvsekiYvyGGkvgrdgsv.sddvyvLdlpsf 42 
                 iPppR++h ++ +++k+Y++GG +   gs+ ++dv+ +d++++
  EEA20674.1 299 IPPPRTNHTTISHNDKLYLFGGTN---GSLwFNDVWCYDPRTN 338
                 7***********************...5665********9997 PP

  == domain 5  score: 17.7 bits;  conditional E-value: 1.2e-06
     Kelch_5   1 iPppRaghcavtvsekiYvyGGkvgrd 27 
                 +P+pR gh+a+  ++ +Yv+GG++  +
  EEA20674.1 349 VPSPREGHAAALIGDTMYVFGGRN--E 373
                 6*********************99..3 PP

  == domain 6  score: 2.5 bits;  conditional E-value: 0.069
     Kelch_5   2 PppRaghcavtvsekiYv 19 
                 P+pR+gh++ + + +i+v
  EEA20674.1 401 PSPRSGHSMTAFGRQIIV 418
                 9*********99999887 PP

>> Kelch_2  Kelch motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.1     0.074   1.7e+02       6      32 ..     134     161 ..     129     174 .. 0.60
   2 !    7.5   0.0    0.0019       4.2       1      48 [.     185     233 ..     185     234 .. 0.79
   3 !   10.5   0.1   0.00021      0.47       1      38 [.     239     273 ..     239     277 .. 0.93
   4 !   41.2   0.6   4.5e-14     1e-10       1      49 []     302     347 ..     302     347 .. 0.96
   5 !    9.1   0.0    0.0006       1.3       2      42 ..     353     391 ..     352     394 .. 0.72
   6 ?    2.2   0.0     0.086   1.9e+02       1      20 [.     403     422 ..     403     440 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.074
     Kelch_2   6 sssvp...ggkiyvvGGahtdnpnlsssdv 32 
                 ++ ++   +g iy++GG    +++ +  d+
  EEA20674.1 134 AINSIaskEGDIYMMGGL--IDGSTVKGDL 161
                 5555555589*******9..4444333333 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0019
     Kelch_2   1 rrgghsssvpggkiyvvGGa..htdnpnlsssdvhvldlekhvWeevtpl 48 
                 +r+gh+s  +g+  +v+GG    +dn++l  ++++ l++++++W++  p+
  EEA20674.1 185 PRVGHASLLVGNAFIVFGGDtkVNDNDVL-DDTLYLLNTSSRQWSRAIPP 233
                 79*****************8744444444.46788999999999987665 PP

  == domain 3  score: 10.5 bits;  conditional E-value: 0.00021
     Kelch_2   1 rrgghsssvpggkiyvvGGahtdnpnlsssdvhvldle 38 
                 +r+gh+   +g+++yv+GG     ++ +++d+  +dl+
  EEA20674.1 239 GRYGHTLNILGSRLYVFGGQ---VDGFFFNDLIAFDLN 273
                 69******************...********9999986 PP

  == domain 4  score: 41.2 bits;  conditional E-value: 4.5e-14
     Kelch_2   1 rrgghsssvpggkiyvvGGahtdnpnlsssdvhvldlekhvWeevtplg 49 
                 +r  h++ + ++k+y++GG    n++l+++dv+++d+++++W+e+ ++g
  EEA20674.1 302 PRTNHTTISHNDKLYLFGGT---NGSLWFNDVWCYDPRTNSWSELDCIG 347
                 6889****************...**********************9986 PP

  == domain 5  score: 9.1 bits;  conditional E-value: 0.0006
     Kelch_2   2 rgghsssvpggkiyvvGGahtdnpnlsssdvhvldlekhvW 42 
                 r gh+++ +g+ +yv+GG+   +++    d+  ++ + ++W
  EEA20674.1 353 REGHAAALIGDTMYVFGGR--NEDGIDLGDLSAFRIGNKRW 391
                 669****************..55555555555555555555 PP

  == domain 6  score: 2.2 bits;  conditional E-value: 0.086
     Kelch_2   1 rrgghsssvpggkiyvvGGa 20 
                 +r+ghs++  g +i+v  G 
  EEA20674.1 403 PRSGHSMTAFGRQIIVLAGE 422
                 79**************9997 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2  14.7      0.16   3.5e+02     165     252 ..     853     934 ..     822     948 .. 0.64
   2 ?   -1.1  26.0      0.31   6.9e+02     145     267 ..     880    1005 ..     868    1014 .. 0.89
   3 ?    2.9  10.4     0.019        42     170     257 ..    1038    1124 ..    1021    1128 .. 0.82
   4 !    6.5  10.8    0.0015       3.3     164     253 ..    1168    1257 ..    1163    1261 .. 0.74
   5 !   16.5  21.4   1.4e-06    0.0031     137     280 ..    1205    1346 ..    1200    1352 .. 0.80

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.16
        Spc7 165 ldellpeleeekaeleeeleklqeaaeelesid.keeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiae 252
                  +++ +         e + e  +++ +ele  +   eLe+lr el +l+a  ++ ++  +e +++ ++++ + eel+++ +++ ++++ 
  EEA20674.1 853 EKRARE-------LAEGTNEATRKRLAELEMQNhASELESLRAELHQLQAHARQESALRSEAEANHKQISIDKEELSQKLEDVTSRLKD 934
                 222222.......2222333334455555555547889999999999999999888888888888888888888888888888887765 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.31
        Spc7  145 eenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeeles..id.keeLeelreelaelkaeieekkkelaelqeqleeleekiee 238 
                   ++le+l+++  +L+++  + ++l  e e+++++++   e+l ++ e+++s   d   ++ +lre++a+  a+    +k l+e +e++e le k+ +
  EEA20674.1  880 ASELESLRAELHQLQAHARQESALRSEAEANHKQISIDKEELSQKLEDVTSrlKDhGGNMTSLREAVAASAAKATLMEKHLEEERERREGLERKLLQ 976 
                  567999999***********************************999999976444789************************************** PP

        Spc7  239 lkeqkseleeeiaeaervleeckgwsese 267 
                  l++ ++e  +e++ a+r l+e ++  es 
  EEA20674.1  977 LRADYEERTAELETANRRLKEAEELAESH 1005
                  *******************9998877765 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.019
        Spc7  170 peleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaervl 257 
                  +++++ +a++e+ ++  ++ ++  ++   ++L+ + e++a l+a  e+ ++e   l++ql++  ++ ++++++ +el++++++++r +
  EEA20674.1 1038 QRVVALQAQVEAAAKLAKS-NQAAADEAADKLRRAEERIAGLEAYQEQVSREGLHLRRQLQTAIKDSQSMATENKELKSQLESQQRDT 1124
                  4455555566555554444.55567788******************************************************999865 PP

  == domain 4  score: 6.5 bits;  conditional E-value: 0.0015
        Spc7  164 eldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaea 253 
                   l +l ++l++  ++ ee+  + +++++e +   +e+Le+l ++ +++   ++  +k+l++++++l++ ++  ++l+++ + ++++++++
  EEA20674.1 1168 RLRDLEQQLQASLKAHEETKVTFESREQEADRTYREKLEQLENDYQSAVHYVKGTEKMLKRMKDELARYKTHAATLQTELEAVQKNVEQS 1257
                  566777777777777777777777777777777788888888888888888888888888888888888888888888888888887775 PP

  == domain 5  score: 16.5 bits;  conditional E-value: 1.4e-06
        Spc7  137 legLkegleenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesid.keeLeelreelaelkaeie.ekkkelaelqeqlee 231 
                  le+L++ +++ +  ++  +++L++ ++el     +++++ a+l+ ele  q+ +e+ +s+  +++ e+ r+el++  ae++ + ++ +++l++q+++
  EEA20674.1 1205 LEQLENDYQSAVHYVKGTEKMLKRMKDELA----RYKTHAATLQTELEAVQKNVEQSSSSPaPASWENERSELQKSLAELQtNMSTSINDLESQITK 1297
                  455555555555555555555555555444....34556678999999999988888888779999999999999999987245689********** PP

        Spc7  232 leekieelkeqkseleeeiaeaervleeckgwsesevsrlkeevkalee 280 
                  l+e++++++++ +e++++ ++a++ l    + s+ e+++lkee + le+
  EEA20674.1 1298 LREDLSTAQTESHETRSAHEAAKKELLTVADRSRAEIEQLKEENSLLES 1346
                  *******************************************999987 PP

>> TPR_MLP1_2  TPR/MLP1/MLP2-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.1         5   1.1e+04      29      48 ..     691     710 ..     687     716 .. 0.43
   2 ?   -1.2   1.1      0.89     2e+03      53      85 ..     753     785 ..     745     797 .. 0.48
   3 ?    1.3  18.4      0.15   3.4e+02      25     114 ..     854     934 ..     820     938 .. 0.49
   4 ?    2.4  16.8     0.068   1.5e+02       3     100 ..     918    1015 ..     917    1024 .. 0.91
   5 ?   -2.3  15.6       1.9   4.2e+03       5     128 ..    1042    1119 ..    1037    1131 .. 0.52
   6 !   17.4  20.7   1.6e-06    0.0036       4     112 ..    1170    1284 ..    1167    1294 .. 0.85
   7 !   12.2  11.9   6.4e-05      0.14      57     126 ..    1293    1362 ..    1285    1364 .. 0.92
   8 ?   -2.7   0.4       2.6   5.8e+03      99      99 ..    1442    1442 ..    1420    1481 .. 0.49

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 5
  TPR_MLP1_2  29 edlekqaeiakeaqqkYere 48 
                 e l k+ e a++ +  Y++e
  EEA20674.1 691 EALIKELEAARNRNAWYASE 710
                 33333333333333333333 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.89
  TPR_MLP1_2  53 aedvkelqalreelnelkaeiaelkaeaesaka 85 
                 ae +k  +++  +++ + +++ae++ ++++a +
  EEA20674.1 753 AELAKMQATVDRQAAIASKRVAEVEHQRDAAIS 785
                 334444444444444444444444444444444 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.15
  TPR_MLP1_2  25 qklqedlekqaeiakeaqqk..Yerelvkhaedvkelqalreelnelkaeiaelkaeaesakaeleeseesweeqkeelekelselekried 114
                 +      ++ ae ++ea +k   e e+++ha+++   ++lr+el++l+a +++      ++++e e++ ++++  keel ++l+++++r++d
  EEA20674.1 854 K----RARELAEGTNEATRKrlAELEMQNHASEL---ESLRAELHQLQAHARQ----ESALRSEAEANHKQISIDKEELSQKLEDVTSRLKD 934
                 2....22333333333333322456666666543...4444444444444433....23345555555566666777777777777777776 PP

  == domain 4  score: 2.4 bits;  conditional E-value: 0.068
  TPR_MLP1_2    3 lksleeeikslkeekeeaeaklqklqedlekqaeiakeaqqkYerelvkhaedvkelqalreelnelkaeiaelkaeaesakaeleeseesweeqke 99  
                  +++l +++++++++ +++  ++++l+e + + a+ a+ +++  e+e    +   ++l +lr++++e +ae+++++ ++++a++  e    + e++k 
  EEA20674.1  918 KEELSQKLEDVTSRLKDHGGNMTSLREAVAASAAKATLMEKHLEEERERREGLERKLLQLRADYEERTAELETANRRLKEAEELAESHAREAESHKL 1014
                  6899999***********************************************************9999999999999999999888888888776 PP

  TPR_MLP1_2  100 e 100 
                  +
  EEA20674.1 1015 A 1015
                  5 PP

  == domain 5  score: -2.3 bits;  conditional E-value: 1.9
  TPR_MLP1_2    5 sleeeikslkeekeeaeaklqklqedlekqaeiakeaqqkYerelvkhaedvkelqalreelnelkaeiaelkaeaesakaeleeseesweeqkeel 101 
                  +l+++++++ + +++ +a++ ++ ++l+                                              +ae+  a le+ +e+ +++  +l
  EEA20674.1 1042 ALQAQVEAAAKLAKSNQAAADEAADKLR----------------------------------------------RAEERIAGLEAYQEQVSREGLHL 1092
                  3444444444444444444444444444..............................................55555555555555555555555 PP

  TPR_MLP1_2  102 ekelselekriedlneqNklLhdQlEs 128 
                  +++l+ + k  + + + Nk L +QlEs
  EEA20674.1 1093 RRQLQTAIKDSQSMATENKELKSQLES 1119
                  555555555555555555555555554 PP

  == domain 6  score: 17.4 bits;  conditional E-value: 1.6e-06
  TPR_MLP1_2    4 ksleeeikslkeekeeaeaklqklqedl.ekqaeiakeaqqkYerelvkhaedvkelqalreelnelkaeiaelkaeaesakaeleesee.....sw 94  
                  + le+++++ ++  ee + ++++ +++  ++ +e +++ +++Y++ +   + + k l+++++el+++k+ +a+l++e+e++++++e+s +     sw
  EEA20674.1 1170 RDLEQQLQASLKAHEETKVTFESREQEAdRTYREKLEQLENDYQSAVHYVKGTEKMLKRMKDELARYKTHAATLQTELEAVQKNVEQSSSspapaSW 1266
                  67888888888888888888888877773567999****************************************************986333337* PP

  TPR_MLP1_2   95 eeqkeelekelselekri 112 
                  e++++el+k l+el++ +
  EEA20674.1 1267 ENERSELQKSLAELQTNM 1284
                  *************99764 PP

  == domain 7  score: 12.2 bits;  conditional E-value: 6.4e-05
  TPR_MLP1_2   57 kelqalreelnelkaeiaelkaeaesakaeleeseesweeqkeelekelselekriedlneqNklLhdQl 126 
                   ++++lre+l+++++e +e +++ e+ak+el +       + e+l++e s le+r    ++  ++L++Q+
  EEA20674.1 1293 SQITKLREDLSTAQTESHETRSAHEAAKKELLTVADRSRAEIEQLKEENSLLESRALHAEQRVTMLLEQM 1362
                  5899999999999999999999999999999999999999999999999999999999999999999997 PP

  == domain 8  score: -2.7 bits;  conditional E-value: 2.6
  TPR_MLP1_2   99 e 99  
                   
  EEA20674.1 1442 R 1442
                  1 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1515 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2285  (0.127447); expected 358.6 (0.02)
Passed bias filter:                      583  (0.0325172); expected 358.6 (0.02)
Passed Vit filter:                       143  (0.0079759); expected 17.9 (0.001)
Passed Fwd filter:                        88  (0.00490825); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 2.21u 0.41s 00:00:02.62 Elapsed: 00:00:00.65
# Mc/sec: 7044.25
//
Query:       EEA20675.1  [L=402]
Description: casein kinase I, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.4e-26   91.5   0.0    7.4e-26   91.1   0.0    1.1  1  Pkinase         Protein kinase domain
    7.5e-14   51.6   0.0    1.1e-13   51.1   0.0    1.2  1  Pkinase_Tyr     Protein tyrosine kinase
    4.2e-09   35.7   0.0    7.4e-09   34.9   0.0    1.3  1  Pkinase_fungal  Fungal protein kinase
    3.8e-05   23.7   0.1     0.0016   18.4   0.0    2.8  3  APH             Phosphotransferase enzyme family


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.1   0.0   1.7e-29   7.4e-26       1     213 [.      12     231 ..      12     261 .. 0.85

  Alignments for each domain:
  == domain 1  score: 91.1 bits;  conditional E-value: 1.7e-29
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHSCTTB--EEEEEEE.SSEEEEEEE--TTEBHHHHHH.HHSS--H CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklkhpnivrlyevfee.kdelylvleyveggeladlle.rkgslse 97 
                 y+  +k+G+GsfG +y +++  +g+++A+K  +++ +      ++  E ++ k+l     + ++++f +  d+  +v +++   +l+dl +  ++++s 
  EEA20675.1  12 YRIGRKIGSGSFGDIYLGTNIISGEEIAIKLESVKAKHP----QLEYEARVYKSLAGGVGIPFVRWFGTeCDYNAMVIDLLGP-SLEDLFNfCNRKFSL 105
                 67899*************************877766665....4569*********888888888888724666699999974.577777765678*** PP

                 HHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEE..TTTE.EEE-SGTTSEESSSSCS........BCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHH CS
     Pkinase  98 eeakkiakqilegleylHskgiiHrDlKpeNiLid..ekge.lKitDFGlakelesssk........ltsfvgtseYlAPEvlkeneyskkvDvWslGv 185
                 +++  +a q+++ +ey+H+k++iHrD+Kp+N+L+   ++g+ + ++DFGlak+++  ++         ++ +gt +Y +     + e s+  D+ slG 
  EEA20675.1 106 KTVLLLADQLISRIEYIHAKSFIHRDIKPDNFLMGigKRGNqVNVIDFGLAKKYRDPKThfhipyreNKNLTGTARYASINTHLGVEQSRRDDMESLGY 204
                 *********************************986555557**************9999******99***********999889999*********** PP

                 HHHHHHHSS-STTTSSHHHHHHHHHHTH CS
     Pkinase 186 ilyelltgkppfsgekgkekvekeldql 213
                 +++ +  g+ p++g k  + +++++d++
  EEA20675.1 205 VMLYFCRGSLPWQGLKAAT-KKQKYDRI 231
                 *************766554.44444442 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.1   0.0   2.4e-17   1.1e-13       3     227 ..      14     239 ..      12     250 .. 0.79

  Alignments for each domain:
  == domain 1  score: 51.1 bits;  conditional E-value: 2.4e-17
                  EEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS.-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHTCTTT CS
  Pkinase_Tyr   3 lgkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkkl.khpnivkllgvctkeepllivteyvkgGdLlkfLrkkekek 99 
                  +g+k+G+G+fG+++ gt       + +++a+K  + +a++    +l  ea++ k+l     i  +  + t+ +   +v++++   +L++  +   ++k
   EEA20675.1  14 IGRKIGSGSFGDIYLGTNI----ISGEEIAIKLESVKAKHP---QLEYEARVYKSLaGGVGIPFVRWFGTECDYNAMVIDLLG-PSLEDLFNFC-NRK 102
                  789**************99....78899****986666666...788899999999444444444444456677889999874.4677777776.778 PP

                  SBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEE...TTEEEE-STTTHEETTTSSEE.....EETTSSTSGGGGS-HHHHHHSEEEHHHHHH CS
  Pkinase_Tyr 100 ltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlse...nkvvkisDfGLardiekddey.....vkkeeaklpvkWmapEslkekkftsksDvW 189
                  ++lk++l +a q+ + +ey+++k+++Hrd+   N L+     +++v + DfGLa++  + ++      +++++ +   ++ ++ +    + + + D+ 
   EEA20675.1 103 FSLKTVLLLADQLISRIEYIHAKSFIHRDIKPDNFLMGIgkrGNQVNVIDFGLAKKYRDPKTHfhipyRENKNLTGTARYASINTHLGVEQSRRDDME 200
                  ************************************97433388***********99555543555558888899999******************** PP

                  HHHHHHHHHHTTSSGTTTTSHHHHHHHHH..HTTEES-BB CS
  Pkinase_Tyr 190 sfGvllwEiftlgespypglkneevlekl..kegkrlekp 227
                  s G ++   +  g+ p++glk+++  +k+    +k++++p
   EEA20675.1 201 SLGYVMLYFCR-GSLPWQGLKAATKKQKYdrIMEKKMTTP 239
                  ***99986555.****999987776555522223344444 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.9   0.0   1.7e-12   7.4e-09     323     408 .]     123     210 ..     104     210 .. 0.89

  Alignments for each domain:
  == domain 1  score: 34.9 bits;  conditional E-value: 1.7e-12
  Pkinase_fungal 323 flkagiLHrDiSenNilitdskkegerkglLiDLDlakelsddsses.....garertGTleFmaievlkgeeHsyrhDLESffyvllwic 408
                     +  + ++HrDi  +N l+     +++++  +iD+ lak++ d++++      ++++ tGT+ + +i+   g e s r+D+ES+ yv+l+ c
      EEA20675.1 123 H-AKSFIHRDIKPDNFLMG--IGKRGNQVNVIDFGLAKKYRDPKTHFhipyrENKNLTGTARYASINTHLGVEQSRRDDMESLGYVMLYFC 210
                     4.6789*************..7788999*************988887666666699*********************************98 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0      0.17   7.5e+02      32      67 ..      47      81 ..      35      90 .. 0.79
   2 !   18.4   0.0   3.6e-07    0.0016     165     197 ..     124     157 ..     101     159 .. 0.88
   3 ?    1.0   0.0     0.073   3.3e+02     129     162 ..     305     337 ..     286     351 .. 0.72

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.17
                S-HHHHHHHHHHHHHHHHTT-B--B-CTTBS-EEET CS
         APH 32 raaeeirrevallrlLakagvpvPevlagdtddeei 67
                  +++++ e+++++ La+  v +P v +++t ++ +
  EEA20675.1 47 AKHPQLEYEARVYKSLAGG-VGIPFVRWFGTECDYN 81
                47899***********966.5568899999998865 PP

  == domain 2  score: 18.4 bits;  conditional E-value: 3.6e-07
                 -EEEE-SS-SGGGEEEC....TTEEEEE---TT-E CS
         APH 165 ptvllHgDlhpgNllvd..pddgrvtGviDfedag 197
                 +++++H+D++p+N+l+   +++++v  viDf++a+
  EEA20675.1 124 AKSFIHRDIKPDNFLMGigKRGNQV-NVIDFGLAK 157
                 689***************9888888.9*****996 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 0.073
                 HHCHHHCCCGCCTCCHHHHHHHHHHHHHHHH--S CS
         APH 129 lesatarllaselldlleeleeqvlaalaallpg 162
                 +++a++++++ e+++ ++++++q++ ala  +pg
  EEA20675.1 305 IVDANNPKKDKETEE-QQRRAAQAAPALANQVPG 337
                 555666777777777.888888888888888887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (402 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       674  (0.0375927); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.30s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 2723.98
//
Query:       EEA20676.1  [L=374]
Description: casein kinase I, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.4e-26   91.8   0.0      6e-26   91.4   0.0    1.1  1  Pkinase         Protein kinase domain
    6.2e-14   51.9   0.0    8.7e-14   51.4   0.0    1.2  1  Pkinase_Tyr     Protein tyrosine kinase
    3.7e-09   35.9   0.0    6.4e-09   35.1   0.0    1.4  1  Pkinase_fungal  Fungal protein kinase
      3e-05   24.1   0.1     0.0015   18.5   0.0    2.8  3  APH             Phosphotransferase enzyme family


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.4   0.0   1.3e-29     6e-26       1     213 [.      12     231 ..      12     261 .. 0.85

  Alignments for each domain:
  == domain 1  score: 91.4 bits;  conditional E-value: 1.3e-29
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHSCTTB--EEEEEEE.SSEEEEEEE--TTEBHHHHHH.HHSS--H CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklkhpnivrlyevfee.kdelylvleyveggeladlle.rkgslse 97 
                 y+  +k+G+GsfG +y +++  +g+++A+K  +++ +      ++  E ++ k+l     + ++++f +  d+  +v +++   +l+dl +  ++++s 
  EEA20676.1  12 YRIGRKIGSGSFGDIYLGTNIISGEEIAIKLESVKAKHP----QLEYEARVYKSLAGGVGIPFVRWFGTeCDYNAMVIDLLGP-SLEDLFNfCNRKFSL 105
                 67899*************************877766665....4569*********888888888888724666699999974.577777765678*** PP

                 HHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEE..TTTE.EEE-SGTTSEESSSSCS........BCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHH CS
     Pkinase  98 eeakkiakqilegleylHskgiiHrDlKpeNiLid..ekge.lKitDFGlakelesssk........ltsfvgtseYlAPEvlkeneyskkvDvWslGv 185
                 +++  +a q+++ +ey+H+k++iHrD+Kp+N+L+   ++g+ + ++DFGlak+++  ++         ++ +gt +Y +     + e s+  D+ slG 
  EEA20676.1 106 KTVLLLADQLISRIEYIHAKSFIHRDIKPDNFLMGigKRGNqVNVIDFGLAKKYRDPKThfhipyreNKNLTGTARYASINTHLGVEQSRRDDMESLGY 204
                 *********************************986555557**************9999******99***********999889999*********** PP

                 HHHHHHHSS-STTTSSHHHHHHHHHHTH CS
     Pkinase 186 ilyelltgkppfsgekgkekvekeldql 213
                 +++ +  g+ p++g k  + +++++d++
  EEA20676.1 205 VMLYFCRGSLPWQGLKAAT-KKQKYDRI 231
                 *************766554.44444442 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.4   0.0     2e-17   8.7e-14       3     227 ..      14     239 ..      12     251 .. 0.79

  Alignments for each domain:
  == domain 1  score: 51.4 bits;  conditional E-value: 2e-17
                  EEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS.-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHTCTTT CS
  Pkinase_Tyr   3 lgkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkkl.khpnivkllgvctkeepllivteyvkgGdLlkfLrkkekek 99 
                  +g+k+G+G+fG+++ gt       + +++a+K  + +a++    +l  ea++ k+l     i  +  + t+ +   +v++++   +L++  +   ++k
   EEA20676.1  14 IGRKIGSGSFGDIYLGTNI----ISGEEIAIKLESVKAKHP---QLEYEARVYKSLaGGVGIPFVRWFGTECDYNAMVIDLLG-PSLEDLFNFC-NRK 102
                  789**************99....78899****986666666...788899999999444444444444456677889999874.4677777776.778 PP

                  SBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEE...TTEEEE-STTTHEETTTSSEE.....EETTSSTSGGGGS-HHHHHHSEEEHHHHHH CS
  Pkinase_Tyr 100 ltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlse...nkvvkisDfGLardiekddey.....vkkeeaklpvkWmapEslkekkftsksDvW 189
                  ++lk++l +a q+ + +ey+++k+++Hrd+   N L+     +++v + DfGLa++  + ++      +++++ +   ++ ++ +    + + + D+ 
   EEA20676.1 103 FSLKTVLLLADQLISRIEYIHAKSFIHRDIKPDNFLMGIgkrGNQVNVIDFGLAKKYRDPKTHfhipyRENKNLTGTARYASINTHLGVEQSRRDDME 200
                  ************************************97433388***********99555543555558888899999******************** PP

                  HHHHHHHHHHTTSSGTTTTSHHHHHHHHH..HTTEES-BB CS
  Pkinase_Tyr 190 sfGvllwEiftlgespypglkneevlekl..kegkrlekp 227
                  s G ++   +  g+ p++glk+++  +k+    +k++++p
   EEA20676.1 201 SLGYVMLYFCR-GSLPWQGLKAATKKQKYdrIMEKKMTTP 239
                  ***99986555.*****99987776555522223344444 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.1   0.0   1.4e-12   6.4e-09     323     408 .]     123     210 ..     103     210 .. 0.89

  Alignments for each domain:
  == domain 1  score: 35.1 bits;  conditional E-value: 1.4e-12
  Pkinase_fungal 323 flkagiLHrDiSenNilitdskkegerkglLiDLDlakelsddsses.....garertGTleFmaievlkgeeHsyrhDLESffyvllwic 408
                     +  + ++HrDi  +N l+     +++++  +iD+ lak++ d++++      ++++ tGT+ + +i+   g e s r+D+ES+ yv+l+ c
      EEA20676.1 123 H-AKSFIHRDIKPDNFLMG--IGKRGNQVNVIDFGLAKKYRDPKTHFhipyrENKNLTGTARYASINTHLGVEQSRRDDMESLGYVMLYFC 210
                     4.6789*************..7788999*************988887666666699*********************************98 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.0      0.14   6.5e+02      32      67 ..      47      81 ..      35      93 .. 0.80
   2 !   18.5   0.0   3.4e-07    0.0015     165     197 ..     124     157 ..     105     159 .. 0.88
   3 ?    1.2   0.0     0.065   2.9e+02     129     162 ..     305     337 ..     285     351 .. 0.72

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.14
                S-HHHHHHHHHHHHHHHHTT-B--B-CTTBS-EEET CS
         APH 32 raaeeirrevallrlLakagvpvPevlagdtddeei 67
                  +++++ e+++++ La+  v +P v +++t ++ +
  EEA20676.1 47 AKHPQLEYEARVYKSLAGG-VGIPFVRWFGTECDYN 81
                47899***********966.5568899999998866 PP

  == domain 2  score: 18.5 bits;  conditional E-value: 3.4e-07
                 -EEEE-SS-SGGGEEEC....TTEEEEE---TT-E CS
         APH 165 ptvllHgDlhpgNllvd..pddgrvtGviDfedag 197
                 +++++H+D++p+N+l+   +++++v  viDf++a+
  EEA20676.1 124 AKSFIHRDIKPDNFLMGigKRGNQV-NVIDFGLAK 157
                 689***************9888888.9*****996 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.065
                 HHCHHHCCCGCCTCCHHHHHHHHHHHHHHHH--S CS
         APH 129 lesatarllaselldlleeleeqvlaalaallpg 162
                 +++a++++++ e+++ ++++++q++ ala  +pg
  EEA20676.1 305 IVDANNPKKDKETEE-QQRRAAQAAPALANQVPG 337
                 555666777777777.888888888888888887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (374 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       585  (0.0326287); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 2576.53
//
Query:       EEA20677.1  [L=292]
Description: bZIP transcription factor (Fcr3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      3e-09   37.1  10.3    1.7e-07   31.4   0.0    2.1  2  PAP1         Transcription factor PAP1
    1.3e-08   34.8  13.8    2.2e-08   34.1  13.8    1.4  1  bZIP_1       bZIP transcription factor
    0.00052   20.0  16.8    0.00059   19.9  15.5    1.7  2  bZIP_2       Basic region leucine zipper
     0.0023   17.7   4.3     0.0033   17.2   4.3    1.2  1  SHE3         SWI5-dependent HO expression protein 3
  ------ inclusion threshold ------
      0.015   13.3   3.6      0.018   13.0   3.6    1.1  1  V_ATPase_I   V-type ATPase 116kDa subunit family
      0.021   15.5   1.1      0.039   14.6   1.1    1.4  1  YabA         Initiation control protein YabA
      0.027   13.8   6.5      0.048   13.0   6.5    1.3  1  DUF4407      Domain of unknown function (DUF4407)
      0.029   14.9  13.6      0.052   14.1  13.6    1.4  1  bZIP_Maf     bZIP Maf transcription factor
      0.067   13.3   2.9      0.087   12.9   2.9    1.2  1  UPF0242      Uncharacterised protein family (UPF0242) N-termi
       0.07   12.9   4.3       0.14   11.9   4.3    1.5  1  DivIC        Septum formation initiator
       0.08   13.2   5.2       0.13   12.4   5.2    1.4  1  TMF_TATA_bd  TATA element modulatory factor 1 TATA binding
        0.1   11.2   4.6       0.12   11.0   4.6    1.0  1  Macoilin     Macoilin family
       0.14   12.6   0.8       0.26   11.7   0.8    1.4  1  FlaC_arch    Flagella accessory protein C (FlaC)
       0.16   11.7   0.2       0.23   11.1   0.2    1.2  1  LamB_YcsF    LamB/YcsF family
        1.2    9.0   6.1        1.8    8.4   6.1    1.3  1  GvpL_GvpF    Gas vesicle synthesis protein GvpL/GvpF
        1.8    8.6  11.6        3.2    7.8  11.6    1.3  1  ADIP         Afadin- and alpha -actinin-Binding
        3.6    8.0   9.1        4.4    7.8   8.2    1.7  1  CENP-H       Centromere protein H (CENP-H)


Domain annotation for each model (and alignments):
>> PAP1  Transcription factor PAP1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   8.6     0.011        11      56     152 ..      55     187 ..       8     208 .. 0.59
   2 !   31.4   0.0   1.6e-10   1.7e-07     308     370 ..     219     281 ..     213     282 .. 0.93

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.011
        PAP1  56 P...................................stsaststtssvesasasssesknqrsnslealtkednnnys.nsaanegltrgstassaesq 118
                 P                                   ++++s++++++++++  + +e+k+ r  +le+   + +++    +a ne+l r+ ++  +e++
  EEA20677.1  55 PgddplgqyifsefiedplavtqrstrssseekdaiTPAQSRRKAQNRAAQ-RAFRERKERRVRELEQKLTDLQAQSMtLHADNERLKRELAKVATENE 152
                 444445555555555555554444444444444443555555555555444.45555555566666665555555544355666666666665444443 PP

        PAP1 119 .sstysansgtstssdSPsssseshqgqlSScgTS 152
                   + +s + ++ +   SP    e+++ ++SS+ TS
  EEA20677.1 153 iLRATSSSGENISAGSSPRGDEEDKEKASSSTSTS 187
                 13334444344444679999998888888888887 PP

  == domain 2  score: 31.4 bits;  conditional E-value: 1.6e-10
        PAP1 308 vvpgedksqmltCtkiWdrlqsmekfrngeiDvDsLCseLrtKArCSegGvVvnqkdvedilk 370
                 v  +e  ++ l+ +  Wd +qs + f+ g +D+ + C  L+t  +C ++G+  ++  v++i++
  EEA20677.1 219 VLSAETGEKLLDTKATWDLIQSHPLFQKGLVDIGDVCERLKTITKCDGQGPAFEEGRVKKIIE 281
                 556788889999999*********************************************996 PP

>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.1  13.8   2.1e-11   2.2e-08       7      63 ..      95     151 ..      93     152 .. 0.95

  Alignments for each domain:
  == domain 1  score: 34.1 bits;  conditional E-value: 2.1e-11
                 XXXX--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1   7 ekrkqkNReaArrsRqRKqaeieeLerrvkaLekeNksLkseleelkkevekLkskv 63 
                  +rk++NR a+r++R+RK+ ++ eLe++   L+++ ++L   +e+lk e +k  +++
  EEA20677.1  95 SRRKAQNRAAQRAFRERKERRVRELEQKLTDLQAQSMTLHADNERLKRELAKVATEN 151
                 69************************************************9987776 PP

>> bZIP_2  Basic region leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9  15.5   5.5e-07   0.00059       6      54 .]      94     143 ..      91     143 .. 0.95
   2 ?    2.9   0.4      0.11   1.1e+02      26      46 ..     136     156 ..     135     159 .. 0.85

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 5.5e-07
                 XXXXX.XXXXXXXX-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_2   6 rerRr.kNreAarrsRekkkakeeeleervkeLeeeNaqLrqkveqLeke 54 
                   rR+ +Nr+A r +Re+k  + +ele+++ +L+++ ++L++ +e L++e
  EEA20677.1  94 QSRRKaQNRAAQRAFRERKERRVRELEQKLTDLQAQSMTLHADNERLKRE 143
                 569999******************************************98 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.11
                 HHHHHHHHHHHHHHHHHHHHH CS
      bZIP_2  26 keeeleervkeLeeeNaqLrq 46 
                  +e l++++ ++ +eN+ Lr+
  EEA20677.1 136 DNERLKRELAKVATENEILRA 156
                 578899999999999999986 PP

>> SHE3  SWI5-dependent HO expression protein 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   4.3   3.2e-06    0.0033      60     106 ..     108     154 ..      76     162 .. 0.85

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 3.2e-06
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH CS
        SHE3  60 lLkRKerrlkdlekelselkesveelklekkqlkkrlenssasetel 106
                 + +RKerr+++le++l++l+ +   l+++++ lk +l +   +++ l
  EEA20677.1 108 FRERKERRVRELEQKLTDLQAQSMTLHADNERLKRELAKVATENEIL 154
                 558*********************************99987776655 PP

>> V_ATPase_I  V-type ATPase 116kDa subunit family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   3.6   1.7e-05     0.018      53     138 ..      98     183 ..      73     218 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 1.7e-05
  V_ATPase_I  53 vikeeeaeesleapeekeldeleeelekleeelkelnenleklkkelnelvelkavlekakefleeeeeeeeeeeseeeeeekeee 138
                 +++++ a++  ++++e+++ ele++l++l+++ ++l++ +e+lk+el ++  ++++l+ +++  e+ ++ ++ + +ee++e+++++
  EEA20677.1  98 KAQNRAAQRAFRERKERRVRELEQKLTDLQAQSMTLHADNERLKRELAKVATENEILRATSSSGENISAGSSPRGDEEDKEKASSS 183
                 22233337888899999*****************************************9998887543333333333332221111 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   1.1   3.7e-05     0.039      10      53 ..     116     173 ..     109     192 .. 0.52

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 3.7e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH..............X CS
        YabA  10 leeleeqleelleeleelkeelaelleenaeLeleneklrerl..............e 53 
                 ++ele++l++l+++  +l+++ ++l  e a++ +ene lr +               +
  EEA20677.1 116 VRELEQKLTDLQAQSMTLHADNERLKRELAKVATENEILRATSssgenisagssprgD 173
                 5555555555555555555555555555555555555555555555555566554331 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   6.5   4.6e-05     0.048      98     225 ..      59     177 ..      58     194 .. 0.58

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 4.6e-05
     DUF4407  98 pleLkiFekeIdaelaeeqqeeakelkeqlaaaltaelaeleaqiaalqaeida.aearldalraeaqkeldgtkgtgttgvaGkgpaakekkaqldaa 195
                 pl + iF++ I+  la +q+++ ++ +e+ a   t+ +++ +aq++a+q+++++ +e+r+++l++++++   +  +          +  ++ k++l++ 
  EEA20677.1  59 PLGQYIFSEFIEDPLAVTQRSTRSSSEEKDA--ITPAQSRRKAQNRAAQRAFRErKERRVRELEQKLTDLQAQSMT-L-------HADNERLKRELAKV 147
                 8999****************99999988866..6777777777776666666541555666666666655444221.1.......22234445555555 PP

     DUF4407 196 qaelaelkakldatarlaalraelaeleae 225
                  +e + l+a+++++++++a  + + + e++
  EEA20677.1 148 ATENEILRATSSSGENISAGSSPRGDEEDK 177
                 555555555555555555544444442222 PP

>> bZIP_Maf  bZIP Maf transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1  13.6     5e-05     0.052      31      91 ..      94     154 ..      76     155 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 5e-05
    bZIP_Maf  31 qrRRrlKNrgyakscrkrrlqqkeelekekeeleeelerlqqelsrlrqekdalkrkneql 91 
                 q RR+ +Nr +++  r+r+  + +ele++ + l+ +   l++ ++rl++e+ ++  +ne l
  EEA20677.1  94 QSRRKAQNRAAQRAFRERKERRVRELEQKLTDLQAQSMTLHADNERLKRELAKVATENEIL 154
                 99*************************************************9999988876 PP

>> UPF0242  Uncharacterised protein family (UPF0242) N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   2.9   8.2e-05     0.087      70     126 ..     101     158 ..      73     208 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 8.2e-05
     UPF0242  70 leekeaklteld.eglktkeealeelqeeeeeLkeeldakeeelerlkeenqqLqekl 126
                 + + ++   e +   +++ e++l +lq++ + L+   +  ++el++   en+ L+   
  EEA20677.1 101 NRAAQRAFRERKeRRVRELEQKLTDLQAQSMTLHADNERLKRELAKVATENEILRATS 158
                 223333333333256888889******************************9998544 PP

>> DivIC  Septum formation initiator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   4.3   0.00014      0.14      17      57 ..     114     153 ..      95     156 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00014
                 XHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC-XXXXXXX CS
       DivIC  17 laykqlkqeiaalqaelaklkaeneeLeaevkdLksdedyi 57 
                 +++++l+q++++lqa+  +l+a+ne+L++e+++   +e+ i
  EEA20677.1 114 RRVRELEQKLTDLQAQSMTLHADNERLKRELAKV-ATENEI 153
                 6889****************************99.576666 PP

>> TMF_TATA_bd  TATA element modulatory factor 1 TATA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   5.2   0.00013      0.13      14      69 ..     109     164 ..      95     185 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00013
  TMF_TATA_bd  14 verlsseirrlEgElaslkeelerleaerdeareeivklmkeneelkelkkeleel 69 
                   er + ++r+lE  l+ l+ +  +l a  +++++e++k+ +ene l++++++ e++
   EEA20677.1 109 RERKERRVRELEQKLTDLQAQSMTLHADNERLKRELAKVATENEILRATSSSGENI 164
                  5777899****************************************999887766 PP

>> Macoilin  Macoilin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   4.6   0.00011      0.12     229     348 ..      70     189 ..      27     229 .. 0.61

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00011
    Macoilin 229 vdpvalsknnhslnkkdsslklpeleyrekkksakssrsdskkkhehnesvdsklq..ekeymenkskskrlsksessgsesellveesvkskssssss 325
                  dp+a++++++  +++++   +p  + r+ ++ a+++   + +k+++ +++++kl+  +++ m+ +++++rl+++ ++  +++ + +  ++s+++ s  
  EEA20677.1  70 EDPLAVTQRSTRSSSEEKDAITPAQSRRKAQNRAAQRAFRE-RKERRVRELEQKLTdlQAQSMTLHADNERLKRELAKVATENEILRATSSSGENISAG 167
                 46888888888888876666666666665555555554444.444455556666551144567888888888888777777766666655555544444 PP

    Macoilin 326 ssnknskkasagsagssnssskk 348
                 ss +  + + +++a+ss+s+s +
  EEA20677.1 168 SSPRGDE-EDKEKASSSTSTSTT 189
                 3332222.222233333333333 PP

>> FlaC_arch  Flagella accessory protein C (FlaC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.8   0.00025      0.26       1      33 [.     115     147 ..     115     152 .. 0.94

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00025
   FlaC_arch   1 ridelEnklsklsteletvkkeneelsksveel 33 
                 r+ elE+kl +l+ +  t+ ++ne l+ ++ ++
  EEA20677.1 115 RVRELEQKLTDLQAQSMTLHADNERLKRELAKV 147
                 899*************************99887 PP

>> LamB_YcsF  LamB/YcsF family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.2   0.00022      0.23     182     228 ..      95     141 ..      77     151 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00022
                 SB---HHHHHHHHHHHHHTSEEEBTTSSEEE---SEEEE-SSSHHHH CS
   LamB_YcsF 182 aviedpeevaervlklveegkvtavdgeevelkadsicvHgDtpeav 228
                 +  + ++++a+r+ +  +e++v++++ + ++l+a+s+ +H D+++  
  EEA20677.1  95 SRRKAQNRAAQRAFRERKERRVRELEQKLTDLQAQSMTLHADNERLK 141
                 456778999*********************************98755 PP

>> GvpL_GvpF  Gas vesicle synthesis protein GvpL/GvpF
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   6.1    0.0018       1.8     146     197 ..      83     141 ..      65     160 .. 0.71

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0018
   GvpL_GvpF 146 ases....gtayllrkrlgqrleealeerreelaeeleeaLaplaeevrerepqd...e 197
                 +se+      a+ +rk++++++++a +er+e+ ++ele++L+ l +++ + + ++   +
  EEA20677.1  83 SSEEkdaiTPAQSRRKAQNRAAQRAFRERKERRVRELEQKLTDLQAQSMTLHADNerlK 141
                 222223444478899*****************************999988888774551 PP

>> ADIP  Afadin- and alpha -actinin-Binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8  11.6     0.003       3.2      62     131 ..      80     150 ..      74     155 .. 0.87

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.003
        ADIP  62 irkleaeierlqskierlktqleqlerela.lvqakerqlekklktleqklknekeelqrlknalqqiktq 131
                  r+ + e++  + + +r k+q+ + +r      +++ r+le+kl++l+++ +++  +++rlk+ l++++t 
  EEA20677.1  80 TRSSSEEKDAITPAQSRRKAQNRAAQRAFReRKERRVRELEQKLTDLQAQSMTLHADNERLKRELAKVATE 150
                 456667778888899999***********9899999****************************9999885 PP

>> CENP-H  Centromere protein H (CENP-H)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   8.2    0.0042       4.4      16      61 ..     110     155 ..      90     189 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0042
      CENP-H  16 lklsqelrelqeeltevekenlrlkrknrelaaellelakekesek 61 
                 ++ ++ +rel+++lt+++++++ l++ n+ l +el++ a e+e  +
  EEA20677.1 110 ERKERRVRELEQKLTDLQAQSMTLHADNERLKRELAKVATENEILR 155
                 5678899****************************87777776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (292 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1764  (0.0983881); expected 358.6 (0.02)
Passed bias filter:                      783  (0.0436723); expected 358.6 (0.02)
Passed Vit filter:                       144  (0.00803168); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              17  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.46
# Mc/sec: 1916.03
//
Query:       EEA20678.1  [L=745]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.2e-16   59.1   0.1    5.2e-16   58.5   0.1    1.3  1  Fungal_trans  Fungal specific transcription factor domain
    1.5e-06   28.2  12.8    2.7e-06   27.4  12.8    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.5   0.1   5.8e-20   5.2e-16       1     194 [.     252     436 ..     252     469 .. 0.82

  Alignments for each domain:
  == domain 1  score: 58.5 bits;  conditional E-value: 5.8e-20
  Fungal_trans   1 ldrffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsL 97 
                   ld +f+nf+p  p+l++++  +++   + + +++   +ll+ ilalG+  +   ++ ++ +  +          r ++++ +     ++sl+++q+L
    EEA20678.1 252 LDAYFDNFQPFSPLLDEETCRSTF--LSGRRKDNRWLALLNIILALGSITAAGVDNHNHRTYFE----------RSMSFL-NFKILGNPSLEVVQTL 335
                   789**************9999999..66667777777777777777776666666555333333..........555555.555666999******* PP

  Fungal_trans  98 .lllelyektssdralherhhgvavrlarslgLhrnpsyvgkks...lwklweeeaesrrRlwwaaFylDktialklGrpp.llddsqinlpLPcdd 189
                    l+  +y+   s  +l + ++g  +r+a++lgL+r+p+  ++ s   ++ ++   +e  rR+ww+  +l+++    lGrp+  ++  +i++ LP   
    EEA20678.1 336 gLMGGWYCHYISQPNLGYALMGASLRMAVTLGLQREPPFDSHMSagvSPARSGY-QEFKRRVWWSLCCLETWGHETLGRPSmDFFRPSITVKLPHLL 431
                   7777899999999**************************998779977777777.999***********************879**********888 PP

  Fungal_trans 190 ddlwe 194
                   d+++ 
    EEA20678.1 432 DNENY 436
                   86655 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.4  12.8     3e-10   2.7e-06       1      38 [.      36      73 ..      36      75 .. 0.87

  Alignments for each domain:
  == domain 1  score: 27.4 bits;  conditional E-value: 3e-10
                SS-HHHHHCT---STSSSS-HHHHHCT..HHHCCCCTCCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkkln..leCtfysessk 38
                +aC++Cr++K++Cd++kP C  C+ +    +C+ y+ + +
  EEA20678.1 36 RACTSCRQRKIRCDGEKP-CEACRWYKkaEQCS-YPGRER 73
                69****************.*****888778999.887766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (745 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       589  (0.0328518); expected 358.6 (0.02)
Passed bias filter:                      375  (0.0209158); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.74u 0.30s 00:00:01.04 Elapsed: 00:00:00.53
# Mc/sec: 4225.17
//
Query:       EEA20679.1  [L=858]
Description: beta-mannosidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-16   60.6   0.3    2.3e-15   57.0   0.0    2.6  2  Mannosidase_ig   Mannosidase Ig/CBM-like domain
    4.2e-11   43.5   0.0    1.1e-10   42.1   0.0    1.8  1  Glyco_hydro_2    Glycosyl hydrolases family 2
     0.0063   16.4   0.1      0.028   14.3   0.0    2.1  3  Glyco_hydro_2_N  Glycosyl hydrolases family 2, sugar binding 
  ------ inclusion threshold ------
       0.02   14.0   0.3      0.064   12.4   0.3    1.7  1  Glyco_hydro_2_C  Glycosyl hydrolases family 2, TIM barrel dom


Domain annotation for each model (and alignments):
>> Mannosidase_ig  Mannosidase Ig/CBM-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0      0.18   8.2e+02      19      74 ..     190     240 ..     187     303 .. 0.69
   2 !   57.0   0.0   5.1e-19   2.3e-15       2      95 .]     687     777 ..     686     777 .. 0.95

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.18
  Mannosidase_ig  19 lelrlidltgkllaets.ttpvtvgansstevaeidvdellaatggadpravvlvar 74 
                     ++l++++   ++l+ ++ + +++ +  s t +a+id +    +   +  ++   ++r
      EEA20679.1 190 VRLEVYSARVADLWPKTtKIDFNGKVASVTAIARIDTSA---S---TLLKDLTASFR 240
                     667777777778887775667777777777777777652...2...33333333333 PP

  == domain 2  score: 57.0 bits;  conditional E-value: 5.1e-19
  Mannosidase_ig   2 klevwvvsdllepv.qgtlelrlidl.tgkllaets.ttpvtvgansstevaeidvdellaatggadpravvlvarledatgevlatnvywpvpl 93 
                     ++e+wv+s++  +v ++t+el+++++ +g+++      +++t++an++t+++++ + + +     a+p+a+vl+arl + +g ++a++v+wp+p+
      EEA20679.1 687 RYELWVASSRQDEVfNATVELQFLSVvSGRDIRAPVlFENITIAANGTTDMITDGIIDHV-----AEPEAHVLSARLWV-NGLIVARDVDWPQPF 775
                     79********************************999******************77665.....56***********8.*************** PP

  Mannosidase_ig  94 Kd 95 
                     K+
      EEA20679.1 776 KY 777
                     *9 PP

>> Glyco_hydro_2  Glycosyl hydrolases family 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.1   0.0   2.5e-14   1.1e-10       7     110 .]     203     309 ..     197     309 .. 0.62

  Alignments for each domain:
  == domain 1  score: 42.1 bits;  conditional E-value: 2.5e-14
                    EEEEEEETC..SEEEEEEEE.EEEEECSSSSCEEEEEEEEETTSTEEEEEEEEEEEESTT-EEEEEEEEEES--BBEC...CCB--EEEEEEEEET CS
  Glyco_hydro_2   7 fvttdlsdd..ksakvevev.elendsdksvevtleteikdaegkkvkeessvlslgngetksiklelevknpklWsp...etPnLYtlkveldkd 96 
                    + +t+++d   k a+v++ +   +++s+  +++t + +++ ++++ + +e+  ++   + +++ ++e++v +p+lW+p   +++ LY++ v+l+ +
     EEA20679.1 203 WPKTTKIDFngKVASVTAIArIDTSASTLLKDLTASFRLSLRGQEIARQENIPVN---NIDQVAQAEFQVSDPELWWPhgyGSQPLYKVSVSLSHN 295
                    5555555533444444444422223444444455554444444444433332222...222233359***************************** PP

                    TEEEEEEEEEE-B- CS
  Glyco_hydro_2  97 gkvidevstrfGfR 110
                    gk+++  s++fG+R
     EEA20679.1 296 GKELHDTSKKFGIR 309
                    *************9 PP

>> Glyco_hydro_2_N  Glycosyl hydrolases family 2, sugar binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   6.3e-06     0.028      36     124 ..      31     122 ..       7     133 .. 0.86
   2 ?   -3.0   0.0       1.3   5.8e+03     155     165 ..     182     192 ..     178     193 .. 0.85
   3 ?   -3.3   0.0       1.6   7.2e+03      94     112 ..     755     773 ..     750     777 .. 0.72

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 6.3e-06
                      CSCEGCGGSEE.ESSSTS.S.TCTTBHHSS-CEEE.EEEEEEE-HHHHHSEEEEEESEEESEEEEEETTEEEEEEE-TTS-EEEEGGGGS-S CS
  Glyco_hydro_2_N  36 vPsdwelqpiy.tnveyp.idvdsadlptvngtgv.YartfeidskwaekkvrllFegvtsasevwvngqevgkrqgsylpfefDltpylse 124
                      +Ps  + + i  +++e+p i +++ + + vn +++ Y++ f+ ++  ++  v+l+F+g ++     ++gq++ + ++ +++  +D+t+ l++
       EEA20679.1  31 IPSTVQQDLIAnNKLENPyIGFNELKARWVNEKSWiYRHAFQQPEIPTGATVVLVFDGLDTFASCKLDGQMILESDNMFMGYRVDVTEALQN 122
                      677777775541457777678999999999999987999************************************************98875 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.3
                      E--EEESEEEE CS
  Glyco_hydro_2_N 155 tlsGiyRdvsL 165
                       ++Gi+Rdv L
       EEA20679.1 182 MTAGIWRDVRL 192
                      579******87 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 1.6
                      EEEEEETTEEEEEEE-TTS CS
  Glyco_hydro_2_N  94 asevwvngqevgkrqgsyl 112
                        ++wvng  v  + +  +
       EEA20679.1 755 SARLWVNGLIVARDVDWPQ 773
                      5689****99987766555 PP

>> Glyco_hydro_2_C  Glycosyl hydrolases family 2, TIM barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.3   1.4e-05     0.064     104     154 ..     409     459 ..     378     465 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 1.4e-05
                      GGGHHHHHHHHHHHHHHHTT-TTEEEEEEEESSCHHHHHHHHHHHHHHH-T CS
  Glyco_hydro_2_C 104 pewlkavldrieelverdkNHpsviiWSlgNEsgagedikalaelikklDp 154
                      p++l  + + +  +v+r + Hps++i+   NE ++ +++++l+  + ++Dp
       EEA20679.1 409 PKMLDSIRQEAIYNVQRLRHHPSIVIYVGNNEDYQVQEHAKLTYDYDDKDP 459
                      67777788888889**************************99887777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (858 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       551  (0.0307323); expected 358.6 (0.02)
Passed bias filter:                      514  (0.0286686); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.70u 0.26s 00:00:00.96 Elapsed: 00:00:00.43
# Mc/sec: 5993.20
//
Query:       EEA20680.1  [L=242]
Description: Phosducin family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    7.7e-14   51.3   0.1      1e-13   50.8   0.1    1.2  1  Phosducin    Phosducin
  ------ inclusion threshold ------
      0.016   15.2   0.0      0.026   14.5   0.0    1.4  1  Thioredoxin  Thioredoxin
      0.082   13.0   2.1       0.18   11.9   2.1    1.5  1  U3_assoc_6   U3 small nucleolar RNA-associated protein 6


Domain annotation for each model (and alignments):
>> Phosducin  Phosducin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.8   0.1   1.7e-17     1e-13      87     249 ..      60     219 ..      36     237 .. 0.81

  Alignments for each domain:
  == domain 1  score: 50.8 bits;  conditional E-value: 1.7e-17
                 HHHHHHHTT----HHHHHHHHHHHHHHHHHHH-------SEEE--SHHHHHHHHHSS-TT-EEEEEEE.-TTSTTHHHHHHHHHHHHHH-TTSEEEEEE CS
   Phosducin  87 lkeyelidkdkddeeflrkyrkqrmdemrqklskgprfkfvlelesgeqfldtidkeqkitlivvhiy.edgvkgtealnssliclaaeyptvkfckvk 184
                 l e + ++ d +de+fl+kyrk+rm e+   l+k   +++v+ l+  +   ++ d    + ++v       g   +  l      la +y  +kfc ++
  EEA20680.1  60 LDELDALE-DEEDEDFLEKYRKKRMAEIS-TLQKASVYNQVYPLQKTDYAKEVTDASADAYVLVNLTSsTGGNTESRVLSEIWRQLAPKYGEIKFCEIR 156
                 55555554.789***************96.79**************999999988877665544333314455566678888889************** PP

                 HHHH--TTSS-TTT-SEEEEEETTEEEEEETTGGGGS-TT--HHHHHHHHHTTT-S---XXXXXX CS
   Phosducin 185 asvigasdrfsrdvlpallvykagellsnfvrvtdqlaedffavdleaflqefgllpekevlvle 249
                        + +     p++lvyk ge+  ++v++ +  +      d+e  l + g + e ++ + +
  EEA20680.1 157 GDMCI--EGYPDRNTPTILVYKDGEIRRQYVTLRELNGVRTKVEDVEKVLVDLGAIKEGDLRLRK 219
                 98753..34555667***************************************99998887655 PP

>> Thioredoxin  Thioredoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.0   4.4e-06     0.026       2     101 ..      98     197 ..      97     199 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 4.4e-06
                  EEESSHHHHHHHHTT..TSSEEEEEEE-TTSHH..HHCHHHHHHHHHHHCTTTSEEEEEETTTSHHHHHHTT-SSSSEEEEEETTEEEEEEESS-HHH CS
  Thioredoxin   2 vlvltkenFeeevak..ekklvlveFyApwCgh..CkalaPeleklaeelkdkvklakvdvdenedlakkyevegiPtlklfkngkevkkyegareke 95 
                  v  l+k+++ +ev +  ++  vlv+ +++  g    + l+  + +la ++  ++k++++  d + +   +   ++ Pt++++k+g+  ++y+  re +
   EEA20680.1  98 VYPLQKTDYAKEVTDasADAYVLVNLTSSTGGNteSRVLSEIWRQLAPKYG-EIKFCEIRGDMCIEGYPD---RNTPTILVYKDGEIRRQYVTLRELN 191
                  56789999*****99778899*********99622689************9.*******99998666666...99***************99999988 PP

                  HHHHHH CS
  Thioredoxin  96 klaafl 101
                   +++++
   EEA20680.1 192 GVRTKV 197
                  776655 PP

>> U3_assoc_6  U3 small nucleolar RNA-associated protein 6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   2.1   2.9e-05      0.18      27      74 ..      46      93 ..      41     103 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 2.9e-05
  U3_assoc_6 27 kkrrkfEyklqrrgkkkedflkYieyElnLeklrkkRrkrlklkkkks 74
                 +rr++E++l+ ++    d l+  e E  Lek rkkR++++   +k+s
  EEA20680.1 46 AQRRAYENRLEDKDLDELDALEDEEDEDFLEKYRKKRMAEISTLQKAS 93
                58**************************************99944444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (242 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       868  (0.0484132); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.30s 00:00:00.81 Elapsed: 00:00:00.48
# Mc/sec: 1525.11
//
Query:       EEA20681.1  [L=917]
Description: Coatomer subunit gamma, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.2e-114  383.7   0.5   1.9e-114  383.1   0.5    1.2  1  Adaptin_N        Adaptin N terminal region
    3.6e-60  202.5   4.0    8.3e-60  201.3   4.0    1.7  1  COP-gamma_platf  Coatomer gamma subunit appendage platform su
    1.8e-32  111.9   0.8    6.7e-32  110.0   0.1    2.4  2  Coatomer_g_Cpla  Coatomer subunit gamma-1 C-terminal appendag
      9e-17   61.2   3.7    3.7e-12   46.5   0.1    5.6  6  HEAT_2           HEAT repeats
    6.2e-08   32.8   9.9     0.0023   18.0   0.2    4.8  5  Cnd1             non-SMC mitotic condensation complex subunit
     0.0016   18.5   5.1       0.39   11.1   0.2    5.1  4  HEAT             HEAT repeat
     0.0072   16.9   0.3        4.4    8.3   0.0    4.4  3  HEAT_PBS         PBS lyase HEAT-like repeat
  ------ inclusion threshold ------
      0.013   16.0   0.7      0.063   13.8   0.7    2.2  1  HEAT_EZ          HEAT-like repeat
      0.057   13.8   0.1       0.28   11.6   0.1    2.2  1  E2F_CC-MB        E2F transcription factor CC-MB domain
      0.065   12.1   0.0       0.79    8.5   0.0    2.2  2  DUF5010          Domain of unknown function (DUF5010)
      0.067   13.4   1.9       0.19   11.9   1.9    1.7  1  DUF2057          Uncharacterized protein conserved in bacteri
        1.5    8.7   5.1         41    4.1   0.1    4.0  5  UNC45-central    Myosin-binding striated muscle assembly cent


Domain annotation for each model (and alignments):
>> Adaptin_N  Adaptin N terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  383.1   0.5  1.2e-117  1.9e-114       3     522 ..      20     555 ..      18     557 .. 0.96

  Alignments for each domain:
  == domain 1  score: 383.1 bits;  conditional E-value: 1.2e-117
                 HHCCHHHHHHCCSSS-SCHHHHHHHHHHHHHHHCT---G.....HHHHHHHCCCCSS-CHHHHHHHHHHHHHCTTSCCHHCCCCHHHHHHCC.SSSHHH CS
   Adaptin_N   3 kriqqelaeilnsnkdddekkkeavkkliylialGedvs.....flffevvklvaskdfelKrlvYlylellaeesedlalLvtnslqkDlk.dpnqli 95 
                 +++ qe a+++ns+++++++++  ++kl+ l+ +Ge+++      lff + kl++ kd++l+++vYl+l++l+ +++d ++++t+ ++kD    ++ ++
  EEA20681.1  20 TTVFQE-ARLFNSSPISPRRCRALLTKLAVLLFTGEKFPsdeatTLFFGISKLFQNKDPSLRQMVYLILKELSTTAQD-VIMSTSIIMKDTAvGSDVVY 116
                 567788.99***************************99999999**********************************.***********655****** PP

                 HHHHHHHHCCC--CCCHHHHHHHHHHHHT-SSHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHCTT-SSH....................HHHHHHHH CS
   Adaptin_N  96 rglALrvLssirvpelaedlapaikkllkdrspyvrkkAalailklykkdpdllrkqlveeikellsdkdp....................gvvlaAva 174
                 r +A+r+L++i+++++++ +++ ik++++d++p+v+++A++++++l+ +  d +r++  +e++e+ s +++                    + +++A+ 
  EEA20681.1 117 RPNAIRGLCRIIDATTVQGIERLIKTAIVDKTPSVSSAALVSSYHLLPIARDVVRRW-QSETQEAASASKTstgflgfssgqshaisqtnyMTQYHAIG 214
                 ********************************************************6.********7666668************************** PP

                 HHHHHHCCCCCCC.HHHHHHHCCHHHHHHCS-HHHHHHHHHHHCC---SSHHHH..HHHHHHHCGGCGCSSCHHHHHHHHHCCHCCCCST.HHHCCHHC CS
   Adaptin_N 175 lleeikkndrlll.kllpklvrrLcnllteldpwlqvkiiklltrlarqepeerskkellesllnllqssnnaVlletvnlivelapkne.livlavna 271
                 ll++++ +dr++l k++++    ++ +  + +p + + +++l  +la+++ ++r  k +++ l  +l++++++V +e++++i ++++ ++  +++av +
  EEA20681.1 215 LLYQMRSHDRMALvKMVQQ----YSAAGAVKSPAAVILLVRLAAKLADEDASLR--KPMMQLLDGWLRHKHDMVNFEAAKAICDMKDVTDaEASQAVHV 307
                 *****99999955555555....5555599************************..89***************************99998778****** PP

                 HHHHHHSSCCTCHHHHHCHHHHHHHHXXTTTTTTTCCCCSXXTTSXHHHHHHHHHHHCCCXXTTTHHHHHHHHHHHTTSSXXHHHHHHHHHHHHHHHHH CS
   Adaptin_N 272 LvrllsskdenlryvaLrtllkivkkepkavqhldlkifllktdddvsirlkaldlllklvdesNvkeivkeLkkyvkevadedfksklvkaIgrlaek 370
                 L+ +lss++  ++++a+r l++ ++ +p+ v +++ +i++l+++ ++si++ a+++llk+++e +v++++k++  +++++ de fk+ +v+aI++l+ k
  EEA20681.1 308 LQLFLSSPRAITKFAAIRILHSFASFKPHVVNQCNQDIESLISNSNRSIATFAITTLLKTGNEASVDRLMKQISGFMADITDE-FKITIVEAIRTLCLK 405
                 ********************************************************************************777.*************** PP

                 SCCHHHHHHHHHHHHHTTXXHHH.HHHHHHHHHHHHHHSTTTSTTCHHHHCCTCCGXXSHHHHHHHHHHHHHTTTTXTT...HHHHHHCTTTTTTTSXH CS
   Adaptin_N 371 fatdaewvldvllellslsgesv.kdeivevirdliqkvpelheeiiekLaellekieseearaaaiWllGeygelvsntesasdllrslaekfvlese 468
                 f+++++++l++l  +l+++g++  k+++ve++ dli+ vp ++e ++++L+e++e++e++++  ++++llG +g+++++   +++++r++++++vle++
  EEA20681.1 406 FPSKQASMLTFLSGILRDEGGYEfKRSVVESMFDLIKFVPGSKEDALAHLCEFIEDCEFTKLSVRILHLLGVEGPKTPQ---PTKYIRYIYNRVVLENA 501
                 ******************998766******************************************************9...***************** PP

                 HHHHHHHHHHHHHHHCXGCC.THXHHHHHHHHHHHXXSHHHHHHHHHHHHHHCC CS
   Adaptin_N 469 kvklqiltalvKlyltspdketqekliqlvlslatssdlevrdRaveylqllss 522
                 +v+++++tal+K+++ ++d e+++++  l++++++++d+evrdRa   l+l+++
  EEA20681.1 502 VVRAAAVTALAKFGVGQQDPEVKRSVSVLLTRCLDDTDDEVRDRAALNLRLMKE 555
                 **********************************************99999886 PP

>> COP-gamma_platf  Coatomer gamma subunit appendage platform subdomain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  201.3   4.0   5.6e-63   8.3e-60       1     152 []     650     800 ..     650     800 .. 0.92

  Alignments for each domain:
  == domain 1  score: 201.3 bits;  conditional E-value: 5.6e-63
  COP-gamma_platf   1 eeyaeqlaaipefaelGkllksskpveLTesetEYvVsvvKhifkehiVlqfnikNtledqvLenvsvqlepeeee.lfeevfiipiekLkyne 93 
                      ++yaeql++ipe++e+G+llkss+ veLTesetEYvVs+vKhifkehiVlq++ kNtl+d+vLe+vsv+++p++ee + ee fi+p++kL++ne
       EEA20681.1 650 QKYAEQLMQIPELKEYGTLLKSSNVVELTESETEYVVSAVKHIFKEHIVLQYDLKNTLPDTVLEDVSVVATPTDEEeELEEDFIVPCPKLPTNE 743
                      69**********************************************************************5554577777************ PP

  COP-gamma_platf  94 pgsvyvvlkrpseeeeklvsatfsntLkFtvkevdpstgepeeedgyeDeYqledlelt 152
                      pg vyv++k++  e++ ++ + f+n+LkFt+ke+dp+tgepee+ gy+DeYq+edl+lt
       EEA20681.1 744 PGIVYVAFKKTGGEHSFPTMS-FTNNLKFTSKEIDPTTGEPEES-GYKDEYQVEDLDLT 800
                      *********986555555555.*******************888.***********985 PP

>> Coatomer_g_Cpla  Coatomer subunit gamma-1 C-terminal appendage platform
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       3.6   5.4e+03       3      41 ..     582     621 ..     581     626 .. 0.70
   2 !  110.0   0.1   4.5e-35   6.7e-32       1     115 []     802     916 ..     802     916 .. 0.98

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 3.6
                      GEEE---S-HHHHHHHH-ST.T-EEEEEEESS---HHHHH CS
  Coatomer_g_Cpla   3 yikpvavsnFeaaWeelese.aeavetfaLssvksleeav 41 
                      y++ +++++F+ a++  +    ++++  a +  k+l++a 
       EEA20681.1 582 YVTATDKETFSVAFDVSSIPvVSHEQALAEERTKKLTSAT 621
                      8999999999999997766545555555557777777776 PP

  == domain 2  score: 110.0 bits;  conditional E-value: 4.5e-35
                      GGGEEE---S-HHHHHHHH-ST.T-EEEEEEESS---HHHHHHHHHHHHT-EE-TTTT---SS-SEEEEEEEEEETTS-EEEEEEEEEE..SS. CS
  Coatomer_g_Cpla   1 sDyikpvavsnFeaaWeelese.aeavetfaLssvksleeavdkliellgmqplegsdkvpenassHtLklaGkfvggekvlvrarlalssskg 93 
                      sDy+ p+++++F+++We+ +++ +ea+etf+Ls+vks+ +a ++li+ l++qpleg+d v+ ++++HtLkl+Gk+v g++++  +++a+s+++g
       EEA20681.1 802 SDYVIPAFAGSFDHVWEQTGANgEEASETFQLSNVKSIADATEQLITALSLQPLEGTD-VALSNTTHTLKLYGKTVSGGRIAGLVKMAFSARTG 894
                      7*********************9***********************************.9999999**************************** PP

                      EEEEEEEEESSHHHHHHHHHH- CS
  Coatomer_g_Cpla  94 vtlkltvRsedeevaelvlsav 115
                      vt k+++Rse+e +a+ ++++v
       EEA20681.1 895 VTTKVSIRSEEEGFAAAIVASV 916
                      *****************99876 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       5.5   8.2e+03      39      58 ..      71      90 ..      68      98 .. 0.68
   2 ?    1.4   0.0      0.29   4.4e+02      15      51 ..     115     155 ..     108     158 .. 0.68
   3 ?    1.7   0.3      0.23   3.5e+02      53      73 ..     235     255 ..     200     265 .. 0.73
   4 ?    3.6   1.0     0.059        88      26      84 ..     255     324 ..     226     328 .. 0.57
   5 ?    5.0   0.0     0.021        32       5      69 ..     308     378 ..     304     382 .. 0.81
   6 !   46.5   0.1   2.4e-15   3.7e-12       1      88 []     452     551 ..     452     551 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 5.5
      HEAT_2 39 llededpavRraaaeaLgai 58
                l +++dp  R+++   L ++
  EEA20681.1 71 LFQNKDPSLRQMVYLILKEL 90
                55777888888887777665 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.29
      HEAT_2  15 evrraairaLgrignpea...lpaLvell.ededpavRraa 51 
                   r +air L ri + ++   ++ L++ +  d+ p v  aa
  EEA20681.1 115 VYRPNAIRGLCRIIDATTvqgIERLIKTAiVDKTPSVSSAA 155
                 45669******998885523356666644477778887777 PP

  == domain 3  score: 1.7 bits;  conditional E-value: 0.23
      HEAT_2  53 eaLgaigdpealpaLkelldd 73 
                  a+ga+++p+a+ +L +l++ 
  EEA20681.1 235 SAAGAVKSPAAVILLVRLAAK 255
                 378999999999999998754 PP

  == domain 4  score: 3.6 bits;  conditional E-value: 0.059
      HEAT_2  26 rignpea......lpaLvellededpavRraaaeaLgaigd......pealpaLkellddddddvvReaAa 84 
                 ++++++a      +++L  +l++++ +v  +aa+a+  ++d      ++a+   ++l+++ + ++++ aA+
  EEA20681.1 255 KLADEDAslrkpmMQLLDGWLRHKHDMVNFEAAKAICDMKDvtdaeaSQAVH-VLQLFLSSPRAITKFAAI 324
                 4444444443333344444678899999999999998887433322133333.344555556666666665 PP

  == domain 5  score: 5.0 bits;  conditional E-value: 0.021
      HEAT_2   5 lqalendpdpevrraairaLgrignp......ealpaLvellededpavRraaaeaLgaigdpealpaLke 69 
                 lq+  ++p   ++ aair L ++++       ++ + + +l++++++ +   a+++L + g++++++ L +
  EEA20681.1 308 LQLFLSSPRAITKFAAIRILHSFASFkphvvnQCNQDIESLISNSNRSIATFAITTLLKTGNEASVDRLMK 378
                 6666678888889999999997766323466677999999**************************99976 PP

  == domain 6  score: 46.5 bits;  conditional E-value: 2.4e-15
      HEAT_2   1 ldaLlqalendpdpevrraairaLg.....rignpealpaLvellededpavRraaaeaLgaig.......dpealpaLkellddddddvvReaAaeaL 87 
                 l++L++++e+++++++  ++++ Lg     + +++++++++ + +  e++ vR+aa++aL+++g        ++++++L+ +++dd+dd+vR +Aa +L
  EEA20681.1 452 LAHLCEFIEDCEFTKLSVRILHLLGvegpkTPQPTKYIRYIYNRVVLENAVVRAAAVTALAKFGvgqqdpeVKRSVSVLLTRCLDDTDDEVRDRAALNL 550
                 579**********************998755566799**************************876664333779*********************998 PP

      HEAT_2  88 a 88 
                 +
  EEA20681.1 551 R 551
                 5 PP

>> Cnd1  non-SMC mitotic condensation complex subunit 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.0      0.15   2.2e+02      59      95 ..      64     100 ..      43     108 .. 0.83
   2 !    8.3   0.0    0.0014       2.1       3      55 ..     117     171 ..     115     180 .. 0.93
   3 !    6.7   0.3    0.0044       6.6      45     143 ..     253     350 ..     239     358 .. 0.81
   4 ?    0.1   0.0      0.48   7.1e+02      61     114 ..     343     390 ..     334     420 .. 0.57
   5 !   18.0   0.2   1.5e-06    0.0023      22     106 ..     488     574 ..     484     619 .. 0.79

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.15
        Cnd1  59 flselaklleDenprVvanalaalteiseksenaiyn 95 
                 +++ + kl ++++p+ ++++ ++l+e+s+ +++ i++
  EEA20681.1  64 LFFGISKLFQNKDPSLRQMVYLILKELSTTAQDVIMS 100
                 778899999999**************99998776655 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.0014
        Cnd1   3 RalairtlgcirvpnlveylvepLrkrLkDedpyVRktaaivvakL..ilndmvk 55 
                 R +air l+ i   ++v+ +   +++++ D+ p V   a++   +L  i +d+v+
  EEA20681.1 117 RPNAIRGLCRIIDATTVQGIERLIKTAIVDKTPSVSSAALVSSYHLlpIARDVVR 171
                 88*******99999********************************999999876 PP

  == domain 3  score: 6.7 bits;  conditional E-value: 0.0044
        Cnd1  45 vakLilndmvkekgflselaklleDenprVvanalaalteiseksenaiynllpdiisklsdalnecsewgqitilefLlsyipkdkqeaeslveklcp 143
                  akL ++d    k +++ l   l+ ++++V   a  a++++++ + +a  ++  ++++ ++++   +++ + i il + +s++p   ++ ++ +e l++
  EEA20681.1 253 AAKLADEDASLRKPMMQLLDGWLRHKHDMVNFEAAKAICDMKDVT-DAEASQAVHVLQLFLSSPRAITKFAAIRILHSFASFKPHVVNQCNQDIESLIS 350
                 356699999999999****************************98.45555667888888889999***************999887777776666665 PP

  == domain 4  score: 0.1 bits;  conditional E-value: 0.48
        Cnd1  61 selaklleDenprVvanalaalteiseksenaiynllpdiisklsdalnecsew 114
                 +++++l++++n+++ + a++ l +  +++   + +l+++i   +     +++ +
  EEA20681.1 343 QDIESLISNSNRSIATFAITTLLKTGNEA--SVDRLMKQISGFMA----DITDE 390
                 56677777777777776666665555543..23333333333333....23333 PP

  == domain 5  score: 18.0 bits;  conditional E-value: 1.5e-06
        Cnd1  22 lvepLrkrLkDedpyVRktaaivvakL.ilndmvkekg.flselaklleDenprVvanalaalteiseksenaiynllpdiisklsd 106
                 ++  +++r+  e++ VR  a+ ++ak  + ++  ++k  +   l ++l+D++++V++ a + l  ++e++e a   ++ d++++ls+
  EEA20681.1 488 YIRYIYNRVVLENAVVRAAAVTALAKFgVGQQDPEVKRsVSVLLTRCLDDTDDEVRDRAALNLRLMKEEDEIANRFVKNDSMYSLST 574
                 678889999999****************555555555527777889************99999999888754444444667777764 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0       1.8   2.7e+03       7      28 ..      70      91 ..      68      93 .. 0.83
   2 ?   -1.5   0.0       2.9   4.4e+03       5      29 ..     307     332 ..     306     333 .. 0.81
   3 ?    4.5   0.2     0.034        50      12      27 ..     499     514 ..     499     516 .. 0.88
   4 !   11.1   0.2   0.00026      0.39       4      25 ..     530     551 ..     527     555 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 1.8
                HHHT-SSHHHHHHHHHHHHHHH CS
        HEAT  7 kllsDpspeVReaAakaLgala 28
                kl + ++p+ R+++ + L +l+
  EEA20681.1 70 KLFQNKDPSLRQMVYLILKELS 91
                778999******9999888875 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 2.9
                 HHHH.HT-SSHHHHHHHHHHHHHHHH CS
        HEAT   5 llkl.lsDpspeVReaAakaLgalae 29 
                 +l+l ls+p +    aA++ L  +a+
  EEA20681.1 307 VLQLfLSSPRAITKFAAIRILHSFAS 332
                 566647999999999****9999987 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.034
                 SSHHHHHHHHHHHHHH CS
        HEAT  12 pspeVReaAakaLgal 27 
                 +++ VR+aA+ aL+++
  EEA20681.1 499 ENAVVRAAAVTALAKF 514
                 5789*********976 PP

  == domain 4  score: 11.1 bits;  conditional E-value: 0.00026
                 HHHHHHT-SSHHHHHHHHHHHH CS
        HEAT   4 lllkllsDpspeVReaAakaLg 25 
                 ll ++l D++ eVR+ Aa++L 
  EEA20681.1 530 LLTRCLDDTDDEVRDRAALNLR 551
                 467788*************996 PP

>> HEAT_PBS  PBS lyase HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.0      0.13   1.9e+02       4      25 ..     285     312 ..     282     314 .. 0.89
   2 ?   -2.2   0.0       6.7     1e+04      15      27 .]     449     461 ..     441     461 .. 0.86
   3 !    8.3   0.0    0.0029       4.4       1      23 [.     503     532 ..     503     536 .. 0.86

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.13
                 HHHHHHHHCTS......GGGHHHHHHHC CS
    HEAT_PBS   4 aAakaLgqlgd......eeaipaLleaL 25 
                 +Aaka+  ++d       +a+ +L+  L
  EEA20681.1 285 EAAKAICDMKDvtdaeaSQAVHVLQLFL 312
                 7**************9999999999877 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 6.7
                 GGGHHHHHHHCTC CS
    HEAT_PBS  15 eeaipaLleaLqd 27 
                 e+a+++L+e  +d
  EEA20681.1 449 EDALAHLCEFIED 461
                 6899***999886 PP

  == domain 3  score: 8.3 bits;  conditional E-value: 0.0029
                 HHHHHHHHHHHCTS.......GGGHHHHHH CS
    HEAT_PBS   1 vRraAakaLgqlgd.......eeaipaLle 23 
                 vR+aA+ aL+++g        ++++ +Ll 
  EEA20681.1 503 VRAAAVTALAKFGVgqqdpevKRSVSVLLT 532
                 9************99999999888888875 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.7   4.2e-05     0.063       3      49 ..     503     547 ..     501     550 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 4.2e-05
     HEAT_EZ   3 vRraAawaLGrlaggepellqplvpeilpaLl.alLnddsdeVRaaAa 49 
                 vR+aA+ aL+     +  ++ p+v++ +  Ll ++L d +deVR  Aa
  EEA20681.1 503 VRAAAVTALA---KFGVGQQDPEVKRSVSVLLtRCLDDTDDEVRDRAA 547
                 8********8...5555566667777777777477777777***9997 PP

>> E2F_CC-MB  E2F transcription factor CC-MB domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.1   0.00019      0.28      16      69 ..     540     593 ..     535     615 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00019
   E2F_CC-MB  16 DelieklteqlknltedeknqlaYvtyedirsiasfkeqtviaikAppgtqlev 69 
                 De+ + +  +l+ ++e+++  + +v+++ + s+++f+ q+v+ ++A    + +v
  EEA20681.1 540 DEVRDRAALNLRLMKEEDEIANRFVKNDSMYSLSTFEHQLVMYVTATDKETFSV 593
                 7888889999**99887777799***********************87766665 PP

>> DUF5010  Domain of unknown function (DUF5010)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.0   0.00053      0.79      33     114 ..      71     155 ..      50     189 .. 0.79
   2 ?    0.8   0.0      0.12   1.8e+02      40      72 ..     784     817 ..     752     836 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00053
     DUF5010  33 lfkpkasdedewWDnlveelayagldfvavnvRGllpeaakdndagdPrklk...dlvaAlkrrgvedklKiaifdDtpaslsaa 114
                 lf+ k+ +  ++   + +el ++ +d+++ +   +++ a   +  ++P++++    +++A   +g+e  +K ai+d tp+  saa
  EEA20681.1  71 LFQNKDPSLRQMVYLILKELSTTAQDVIMSTSIIMKDTAVGSDVVYRPNAIRglcRIIDATTVQGIERLIKTAIVDKTPSVSSAA 155
                 6666666677777778899********999998888888888888899876511167899999****************966654 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.12
     DUF5010  40 dedewWDnl.veelayagldfvavnvRGllpeaa 72 
                 +e+++ D++ ve+l  +g d+v+++  G  ++  
  EEA20681.1 784 EESGYKDEYqVEDLDLTGSDYVIPAFAGSFDHVW 817
                 56788888779**************999877544 PP

>> DUF2057  Uncharacterized protein conserved in bacteria (DUF2057)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   1.9   0.00013      0.19      78     176 ..     562     658 ..     532     665 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00013
     DUF2057  78 elpklenerqakafakspkitltdksgksveakqdklkkegfqlgrdyeqelaeynrsgaaaaaataatataataavaaaaskssataqgqnqaeqmLq 176
                 ++ k +++     f+++  + +t ++++++++  d+     ++   ++ +e  + ++  +a+++ +a+++t ++a+++ aa+ ++++a +q+ aeq +q
  EEA20681.1 562 RFVKNDSMYSLSTFEHQLVMYVTATDKETFSVAFDVSSIPVVSHEQALAEE--RTKKLTSATPTLKAPSTTPTKAKANGAAEGAATAAATQKYAEQLMQ 658
                 556667777788899999999999999998888888887778877777777..444444444568999999*************************766 PP

>> UNC45-central  Myosin-binding striated muscle assembly central
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.72   1.1e+03      12      35 ..      73      96 ..      41     108 .. 0.80
   2 ?   -3.5   0.0         6     9e+03      12      32 ..     145     165 ..     129     182 .. 0.55
   3 ?   -2.5   0.1         3   4.5e+03     129     150 ..     227     248 ..     221     249 .. 0.89
   4 ?    4.1   0.1     0.028        41      15      67 ..     350     402 ..     324     454 .. 0.82
   5 ?    3.8   0.0     0.033        50       4      39 ..     509     544 ..     494     598 .. 0.85

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.72
                   T---TTHHHHHHHHHHHHHHHHHH CS
  UNC45-central 12 mrqpesvrslallilsklldaake 35
                   +++ +s+r++++lil  l  +a++
     EEA20681.1 73 QNKDPSLRQMVYLILKELSTTAQD 96
                   378999*********998877666 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 6
                    T---TTHHHHHHHHHHHHHHH CS
  UNC45-central  12 mrqpesvrslallilskllda 32 
                     ++++sv s al+    ll  
     EEA20681.1 145 VDKTPSVSSAALVSSYHLLPI 165
                    445555555555554444433 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 3
                    HHHHHH-SSHH..HHHHHHTTS CS
  UNC45-central 129 LeelvkssddeklvkalAavvL 150
                    L ++v++++    vk  Aav+L
     EEA20681.1 227 LVKMVQQYSAAGAVKSPAAVIL 248
                    8899999999999*******99 PP

  == domain 4  score: 4.1 bits;  conditional E-value: 0.028
                    -TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCTHHHHHHHHHHHHHH CS
  UNC45-central  15 pesvrslallilsklldaakeefeeaiseflesllekgdeddllnalsvltal 67 
                    ++s rs+a+ +++ ll++ +e+  + + + ++  +++++++ ++ +++++ +l
     EEA20681.1 350 SNSNRSIATFAITTLLKTGNEASVDRLMKQISGFMADITDEFKITIVEAIRTL 402
                    56789***********9999999999999999999999999888888877554 PP

  == domain 5  score: 3.8 bits;  conditional E-value: 0.033
                    HHHHHHC-T---TTHHHHHHHHHHHHHHHHHHHHHH CS
  UNC45-central   4 dlllkfldmrqpesvrslallilsklldaakeefee 39 
                    + l kf   +q ++v+  ++++l+++ld + +e ++
     EEA20681.1 509 TALAKFGVGQQDPEVKRSVSVLLTRCLDDTDDEVRD 544
                    5566666678999**************888887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (917 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       631  (0.0351944); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.75u 0.31s 00:00:01.06 Elapsed: 00:00:00.48
# Mc/sec: 5782.05
//
Query:       EEA20682.1  [L=398]
Description: F-box domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.2e-08   33.0   0.1    1.1e-07   31.7   0.1    1.8  1  F-box-like  F-box-like
  ------ inclusion threshold ------
        2.2    8.8  12.1          5    7.7   0.2    4.4  6  LRR_4       Leucine Rich repeats (2 copies)


Domain annotation for each model (and alignments):
>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.7   0.1   1.2e-11   1.1e-07       3      47 ..      23      73 ..      21      74 .. 0.81

  Alignments for each domain:
  == domain 1  score: 31.7 bits;  conditional E-value: 1.2e-11
  F-box-like  3 rLPdEiLlqIFsyLppsd........LlrlalVCrrWrrvaldtplLWrrlvl 47
                 +P+Ei+lqI s+L+ s          ++++lV+ +W+++al+  +L++r+ l
  EEA20682.1 23 FIPTEIILQIVSRLDSSLggherqrtFYNVCLVSHQWYSAALS--FLYSRPRL 73
                68**********99755233345555***************65..8***9976 PP

>> LRR_4  Leucine Rich repeats (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.2   0.00056         5      15      31 ..     148     164 ..     143     179 .. 0.85
   2 ?    2.2   0.1     0.031   2.7e+02       2      10 ..     157     165 ..     157     198 .. 0.55
   3 ?    5.8   0.2    0.0021        19       1      29 [.     211     240 ..     211     254 .. 0.69
   4 ?    2.0   1.1     0.035   3.2e+02       2      32 ..     235     272 ..     234     279 .. 0.59
   5 ?   -3.6   0.0       1.9   1.7e+04      22      30 ..     289     297 ..     286     297 .. 0.76
   6 ?   -3.6   0.1       1.9   1.7e+04      16      26 ..     341     352 ..     332     352 .. 0.65

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00056
                 E-S-HHH-TT--EEE-. CS
       LRR_4  15 diplleklpnLkeLdLs 31 
                  +++l+k+ nL++LdLs
  EEA20682.1 148 CLSPLSKCANLRYLDLS 164
                 6889999********93 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.031
                 S--EEE--S CS
       LRR_4   2 nLevLdLsn 10 
                 nL++LdLs 
  EEA20682.1 157 NLRYLDLSL 165
                 788888873 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.0021
                 SS--EEE--S...S---.E-S-HHH-TT--EEE CS
       LRR_4   1 pnLevLdLsn...Nqlt.diplleklpnLkeLd 29 
                 pnLe+L Ls+   +++  +++++e   n+++L+
  EEA20682.1 211 PNLETLQLSGtieTRMMdTFDWPE---NMTQLY 240
                 799999999855565554888855...455555 PP

  == domain 4  score: 2.0 bits;  conditional E-value: 0.035
                 S--EEE--SS-.........--E-S-HHH-TT--EEE-.- CS
       LRR_4   2 nLevLdLsnNq.........ltdiplleklpnLkeLdLsg 32 
                 n + L+L+n++         + + p l   ++Lk+L++s 
  EEA20682.1 235 NMTQLYLRNCMnlsleimtgILSNPQLD--TKLKQLTIST 272
                 6677888887445555544444444455..5577777754 PP

  == domain 5  score: -3.6 bits;  conditional E-value: 1.9
                 -TT--EEE- CS
       LRR_4  22 lpnLkeLdL 30 
                 lpnL  L++
  EEA20682.1 289 LPNLLFLSI 297
                 889988875 PP

  == domain 6  score: -3.6 bits;  conditional E-value: 1.9
                 -S-HHH.-TT-- CS
       LRR_4  16 ipllek.lpnLk 26 
                 i+ll + lp+L+
  EEA20682.1 341 IDLLDSsLPHLR 352
                 556664488885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (398 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       369  (0.0205812); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2627.92
//
Query:       EEA20683.1  [L=97]
Description: hypothetical protein PMAA_045090 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (97 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       399  (0.0222544); expected 358.6 (0.02)
Passed bias filter:                      339  (0.0189079); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.24s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 692.86
//
Query:       EEA20684.1  [L=117]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (117 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       787  (0.0438954); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.28s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 833.96
//
Query:       EEA20685.1  [L=105]
Description: mitochondrial genome maintenance protein Mgr2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-25   88.7  17.5    2.8e-25   88.5  17.5    1.1  1  Romo1     Reactive mitochondrial oxygen species modulator 1
  ------ inclusion threshold ------
      0.036   14.4   3.9      0.041   14.3   3.9    1.1  1  Tim17     Tim17/Tim22/Tim23/Pmp24 family


Domain annotation for each model (and alignments):
>> Romo1  Reactive mitochondrial oxygen species modulator 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.5  17.5   3.1e-29   2.8e-25       1      66 []      14      79 ..      14      79 .. 0.98

  Alignments for each domain:
  == domain 1  score: 88.5 bits;  conditional E-value: 3.1e-29
       Romo1  1 scldkikmGalmGaaVGlaiGllfGtfsalryglrgrgllrtlgksmlgsaatFGfFmsiGsviRc 66
                s+l+k+kmGalmG+ VG+++G++ G +s+++yg++++g++rtlgk+mlgs+atFG+FmsiGs+iR+
  EEA20685.1 14 STLEKMKMGALMGTSVGMIMGFIGGAVSIFQYGAGPNGVMRTLGKFMLGSGATFGMFMSIGSIIRT 79
                689**************************************************************7 PP

>> Tim17  Tim17/Tim22/Tim23/Pmp24 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   3.9   4.6e-06     0.041       4      62 ..      18      73 ..      15      90 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 4.6e-06
       Tim17  4 ktglsgvlGallGavfglvkgsrradtpapskerlreglrsvgkrgpslGknfgvvggl 62
                k  +++++G  +G+++g++ g+ + ++   ++   + ++r +gk +  +G +fg+++ +
  EEA20685.1 18 KMKMGALMGTSVGMIMGFIGGAVSIFQ---YGAGPNGVMRTLGKFMLGSGATFGMFMSI 73
                667899********************5...*************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (105 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       336  (0.0187406); expected 358.6 (0.02)
Passed bias filter:                      208  (0.0116013); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.28s 00:00:00.70 Elapsed: 00:00:00.46
# Mc/sec: 692.45
//
Query:       EEA20686.1  [L=739]
Description: cytoplasm to vacuole targeting Vps64, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.2e-17   61.2   0.0    2.4e-16   59.8   0.0    1.8  1  FHA           FHA domain
    0.00033   20.9   0.0     0.0011   19.3   0.0    1.9  1  Yop-YscD_cpl  Inner membrane component of T3SS, cytoplasmic d


Domain annotation for each model (and alignments):
>> FHA  FHA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.8   0.0   2.7e-20   2.4e-16       2      69 .]     193     270 ..     192     270 .. 0.87

  Alignments for each domain:
  == domain 1  score: 59.8 bits;  conditional E-value: 2.7e-20
                 EEESS.......TTSSEETTSTTSTTTEEEEEEETTCEEEEEEEESSSSSEEETTEEEST....TSEEEE-TTEEEEET CS
         FHA   2 tiGRs.......sdcdivlddpsiSrkHalikfdkgsgkvyleDlgSknGtfvNgqrigk....gepveLksgdvielG 69 
                 +iGR         + +  +d++++Sr+Ha+i+ d   gk++++D++S+nGtfvNgqr+++    +ep+eL+++d ++lG
  EEA20686.1 193 RIGRQtnaktipTPVNGYFDSKVLSRQHAEIWADRR-GKIWIRDIKSSNGTFVNGQRLSPesreSEPHELRENDALDLG 270
                 69999755444444455566999************9.***************************************998 PP

>> Yop-YscD_cpl  Inner membrane component of T3SS, cytoplasmic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.0   1.2e-07    0.0011      34      83 ..     214     271 ..     186     275 .. 0.87

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 1.2e-07
                   TTS-TT-EEEEEE.TTEEEEEE-CESS--EETTEE-S..ECC......--TTSEEEETT CS
  Yop-YscD_cpl  34 kevsrkhlkLeve.eesvrledlgsrngllvngerve..ele......lrpgdvlelGt 83 
                   k +sr+h+++ ++   +++++d +s ng++vng+r +  +        lr +d+l lG+
    EEA20686.1 214 KVLSRQHAEIWADrRGKIWIRDIKSSNGTFVNGQRLSpeS-ResepheLRENDALDLGI 271
                   5579********95668******************99752.235688999999999995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (739 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2023  (0.112834); expected 358.6 (0.02)
Passed bias filter:                      692  (0.0385967); expected 358.6 (0.02)
Passed Vit filter:                       100  (0.00557756); expected 17.9 (0.001)
Passed Fwd filter:                        31  (0.00172904); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 1.02u 0.31s 00:00:01.33 Elapsed: 00:00:00.51
# Mc/sec: 4342.65
//
Query:       EEA20687.1  [L=305]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.6e-50  168.9  13.1      5e-48  162.5  13.1    2.8  1  Rpp20           Rpp20 subunit of nuclear RNase MRP and P
    5.5e-17   61.4   0.1      1e-16   60.5   0.1    1.4  1  Alba            Alba
  ------ inclusion threshold ------
      0.022   13.1   9.8      0.027   12.8   9.8    1.2  1  CDC45           CDC45-like protein
       0.22   11.5   1.0       0.51   10.3   1.0    1.6  1  DUF2786         Protein of unknown function (DUF2786)
       0.26   12.3  18.3       0.68   11.0  18.3    1.7  1  Spt5_N          Spt5 transcription elongation factor, acidic 


Domain annotation for each model (and alignments):
>> Rpp20  Rpp20 subunit of nuclear RNase MRP and P
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  162.5  13.1   1.4e-51     5e-48       2     137 .]      85     301 ..      84     301 .. 0.97

  Alignments for each domain:
  == domain 1  score: 162.5 bits;  conditional E-value: 1.4e-51
       Rpp20   2 vpktiyVssktpfmsavkRvqklLeqaekrataslal.......eqkkkeekkklealekkeeelkkeeVfvkatGrAiekalsvgrwfqeke.....e 88 
                 vpk++yVssktpfmsavkRvqklL+ ae+ra+++l+        +q++ ++++ ++ lek++++l++++V+vkatGrAiekalsvgrwf+e +     e
  EEA20687.1  85 VPKIVYVSSKTPFMSAVKRVQKLLRLAERRAMMPLIGkrrhshhHQQYGAKGGGGDVLEKCQKKLREDKVLVKATGRAIEKALSVGRWFEEGKggsgeE 183
                 79*********************************99******99999*****************************************666668889* PP

       Rpp20  89 ykvrvetgsVevvDdivedeeek.....................................................................ankaaed 118
                 ++v ++tgsV+vvDdive++ e+                                                                     + ka++d
  EEA20687.1 184 FEVVIRTGSVCVVDDIVEEDVEDheedeedeedgeekegsidpdinmakinttdntnedlttttqdhkdgdrgeesknqrrrrrkrerireqRLKAFVD 282
                 ********************999*********************************************************************999**** PP

       Rpp20 119 edeeepetrtRwvsmveva 137
                 ed+e+pe+rtRwv+mveva
  EEA20687.1 283 EDGETPESRTRWVNMVEVA 301
                 *****************97 PP

>> Alba  Alba
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.5   0.1   2.8e-20     1e-16       1      54 [.      87     178 ..      87     192 .. 0.94

  Alignments for each domain:
  == domain 1  score: 60.5 bits;  conditional E-value: 2.8e-20
                 CEEEE-STS-HHHHHHHHHHHH......................................THTTESEEEEEEETTHHHHHHHHHHHHHHHTC CS
        Alba   1 neiyVsskspimsyvkralklL......................................snkkeeeVvlkatGraIskAvsvaeilkrrfg 54 
                 +++yVssk+p+ms+vkr++klL                                      +++ e+ V++katGraI+kA+sv++++++  g
  EEA20687.1  87 KIVYVSSKTPFMSAVKRVQKLLrlaerrammpligkrrhshhhqqygakggggdvlekcqKKLREDKVLVKATGRAIEKALSVGRWFEEGKG 178
                 68*********************************************************99999***********************98765 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   9.8   7.5e-06     0.027     131     205 ..     201     276 ..     122     298 .. 0.59

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 7.5e-06
       CDC45 131 esdeedeeeeeeddddeeeeeeeeedeedeeedeeeskkkrk....sksdeeeesddddersrkrrrsepsakklrrql 205
                 e+d ed +ee+e+d++++ee+e + d + + ++ +++++ ++    +++d+++  d+ +e++++rrr++ ++++ r+q+
  EEA20687.1 201 EEDVED-HEEDEEDEEDGEEKEGSIDPDINMAKINTTDNTNEdlttTTQDHKDG-DRGEESKNQRRRRR-KRERIREQR 276
                 222222.22222333333333333333333333322222222233222222222.22222222222222.122233332 PP

>> DUF2786  Protein of unknown function (DUF2786)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   1.0   0.00014      0.51       2      15 ..     100     113 ..      99     115 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00014
     DUF2786   2 ilekIrKLLalAes 15 
                 ++ +++KLL+lAe+
  EEA20687.1 100 AVKRVQKLLRLAER 113
                 678*********97 PP

>> Spt5_N  Spt5 transcription elongation factor, acidic N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0  18.3   0.00019      0.68       4      58 ..     200     276 ..     196     294 .. 0.53

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00019
                 XXXXXXXXXXXXXXXXXXXXXXX.......................XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
      Spt5_N   4 deAeVdddeeeeeeeeeveggedd......................fiaeeeaeeeeedserddrshreldrrrqae 58 
                 +e +V+d ee+ee+ee++e++e +                        ++++  +  e+s++++r++r+ +r r+++
  EEA20687.1 200 VEEDVEDHEEDEEDEEDGEEKEGSidpdinmakinttdntnedlttTTQDHKDGDRGEESKNQRRRRRKRERIREQR 276
                 57788888888888888888887777777666555443333332221111222222222333444444444444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (305 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1633  (0.0910815); expected 358.6 (0.02)
Passed bias filter:                      564  (0.0314574); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.62u 0.33s 00:00:00.95 Elapsed: 00:00:00.49
# Mc/sec: 1880.59
//
Query:       EEA20688.1  [L=438]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (438 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1474  (0.0822132); expected 358.6 (0.02)
Passed bias filter:                      410  (0.022868); expected 358.6 (0.02)
Passed Vit filter:                        75  (0.00418317); expected 17.9 (0.001)
Passed Fwd filter:                        22  (0.00122706); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.74u 0.29s 00:00:01.03 Elapsed: 00:00:00.44
# Mc/sec: 2999.18
//
Query:       EEA20689.1  [L=463]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (463 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       848  (0.0472977); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 3082.52
//
Query:       EEA20690.1  [L=1490]
Description: UDP-glucose:glycoprotein glucosyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.6e-148  493.4   1.8   2.8e-148  492.6   1.8    1.4  1  Glyco_transf_24  Glucosyltransferase 24
    1.5e-65  221.7   0.0    8.6e-64  215.9   0.0    2.5  2  Thioredoxin_14   Thioredoxin-like domain
    4.3e-50  170.2   0.0    2.1e-49  168.0   0.0    2.3  2  Thioredoxin_12   Thioredoxin-like domain
    7.3e-46  156.8   0.2    3.4e-43  148.1   0.0    2.9  3  Thioredoxin_15   Thioredoxin-like domain
    1.3e-41  141.7   1.2    2.5e-40  137.5   0.0    3.4  5  Thioredoxin_13   Thioredoxin-like domain
    6.1e-40  135.7   0.0    1.4e-39  134.6   0.0    1.6  1  UDP-g_GGTase     UDP-glucose:Glycoprotein Glucosyltransferase
     0.0014   18.2   0.0     0.0026   17.3   0.0    1.3  1  Glyco_transf_8   Glycosyl transferase family 8


Domain annotation for each model (and alignments):
>> Glyco_transf_24  Glucosyltransferase 24
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  492.6   1.8  1.1e-151  2.8e-148       1     268 []    1188    1455 ..    1188    1455 .. 0.99

  Alignments for each domain:
  == domain 1  score: 492.6 bits;  conditional E-value: 1.1e-151
  Glyco_transf_24    1 inifsvasGklyerllkimilsvlkktkksvkfwlienflspkfkellpklakkygfeyelvtykwPkwlrkqkekqriiwgykilfldvlf 92  
                       inifsvasG+lyer+l+im++sv+k+t++svkfw+ie+flsp+fk++lp+la++ygf+ye+vtykwP+wlr q+ekqr iwgykilfldvlf
       EEA20690.1 1188 INIFSVASGHLYERMLNIMMVSVMKNTNHSVKFWFIEQFLSPSFKSFLPHLAEEYGFTYEMVTYKWPHWLRGQREKQREIWGYKILFLDVLF 1279
                       89****************************************************************************************** PP

  Glyco_transf_24   93 PldldkvifvdadqvvradlkelveldlegapygytPlcdsrkemegfrfwkqgywkehlkgkkyhisalyvvdlkrfrklaagdrlraqyq 184 
                       Pl+ldkvifvdadq+vr+d+ +lv+ldlegapyg+tP+cdsr+emegfrfwkqgywk+ l++ kyhisalyvvdl+rfr+laagdrlr qyq
       EEA20690.1 1280 PLSLDKVIFVDADQIVRTDMYDLVTLDLEGAPYGFTPMCDSREEMEGFRFWKQGYWKSYLRDLKYHISALYVVDLQRFRELAAGDRLRGQYQ 1371
                       ******************************************************************************************** PP

  Glyco_transf_24  185 klsadpnslanldqdlPnnlqeevpifslpqewlwcetwcsdeskkkaktidlcnnPltkepklerakrlieeweeldeevkel 268 
                       +lsadp+slanldqdlPn++q+ +pi+slpq+wlwcetwcsde++k+aktidlcnnPltkepklera+r+++ew+ +d+e++el
       EEA20690.1 1372 ALSADPESLANLDQDLPNHMQTLIPIKSLPQDWLWCETWCSDEALKTAKTIDLCNNPLTKEPKLERARRQVPEWTVYDDEIAEL 1455
                       ********************************************************************************9875 PP

>> Thioredoxin_14  Thioredoxin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  215.9   0.0   3.3e-67   8.6e-64       1     254 []     413     657 ..     413     657 .. 0.90
   2 ?    3.0   0.0     0.033        84     149     200 ..     760     811 ..     711     829 .. 0.72

  Alignments for each domain:
  == domain 1  score: 215.9 bits;  conditional E-value: 3.3e-67
                     B---SGGGTTTS---S--SSS-SSSTTS---HHHHHS--SSS.----SS--EEEEEEEESS-HHHHHHHHTHHHHHHHTT-SEEEEEEEE-..SS CS
  Thioredoxin_14   1 fdirdrkeggdailwlNdLEkDkrYsrWpsslqellrplypgqlpsirkNlfnlVlvlDlsqredllelltllqsfiqrniPiRfGlVplvsses 95 
                     +d+rd++egg++++wlNdLEkDkrY+ +p++lq+ll+p+ypgq+ps+ ++++n+V+++Dl++ +d++++ + l +fi+r iP+RfGlV+    ++
      EEA20690.1 413 YDWRDEIEGGGVVVWLNDLEKDKRYATFPKTLQALLQPTYPGQFPSVGRDIQNVVVPIDLANVDDVQFVAKYLYAFIKRLIPVRFGLVLTA--NT 505
                     7****************************************************************************************99..66 PP

                     HHHHHHHHHHHHHHHTT-HHHHHHHHHH.HH..HT-.SSS--..HHHHHHHHHHH..........SS----TT...........TTHHHHHHHHH CS
  Thioredoxin_14  96 edskklaklfyylaenygakaaleflta.leakakk.skepdltkevvesafkea..........ldealkseveeileaeitseydealkasre 178
                     e+sk++ak+ +yl++ yg++++l++l+a l++++ +  ++p+     +e+a++e+          ++e+l+se           ++d+ + ++++
      EEA20690.1 506 EESKAQAKIAHYLHQAYGLASLLQYLEAsLASEKVShAHKPS-----FEAAIAERslrpdqeslsFEEILQSE-----------ALDATVANTEK 584
                     6699************************75544444333344.....66666555555556666666666666...........79999****** PP

                     HHHHTT--SSS-EEEE.TTEEEESSSSHHHHHHHHHHHHHHHHHHHHHTT---SS--GGGGT..TTS-BSS--TTT CS
  Thioredoxin_14 179 fikrlglkeaqepvfllNGvvlpfdekweqallaelqedlqelqkavyegiltddddvkdllldlegalkrrnpli 254
                     ++krl+lk  ++p ++ NG+ +++ e+++q+l ++l++dlq +q+ +++g ++d d ++d++  l++a+++rn+ i
      EEA20690.1 585 YLKRLALKGPSPPTLV-NGIAMSRGENYLQELPMQLSRDLQIIQQGLMQGVFSDYDYIPDYF--LSQATQSRNEWI 657
                     ********99899999.*********************************************..*********987 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.033
                     SS----TT............TTHHHHHHHHHHHHHTT--SSS-EEEE.TTEEE CS
  Thioredoxin_14 149 ldealkseveeil.eaeitseydealkasrefikrlglkeaqepvfllNGvvl 200
                     ld++l + +++   +a +++e ++  ++ ++++  lgl++  +  ++lNG+v+
      EEA20690.1 760 LDDVLAQIQSDGShQATQKEEEQAYWTQVQQLVTDLGLSAG-NSTLILNGRVV 811
                     55555555555554555566656779999*********766.555555**997 PP

>> Thioredoxin_12  Thioredoxin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  168.0   0.0     8e-53   2.1e-49       2     188 ..      39     221 ..      38     225 .. 0.93
   2 ?   -3.8   0.0       3.8   9.9e+03      13      27 ..     777     791 ..     775     801 .. 0.82

  Alignments for each domain:
  == domain 1  score: 168.0 bits;  conditional E-value: 8e-53
                     --HHHHHHHHHSSS-HHHHHHHHHHH...HTTGGGS--SHHHHHHHHHHHHHH..S-.-HHHHHHHHHHHHHTTTHHHHHHHHHHHHHTT..... CS
  Thioredoxin_12   2 tPlllealEtlakenedlFwefvdaleelaeeesaesssdkelyeailklaes..ll.seealslfelsLalrsasPrieafyqlaeeslssl.. 91 
                      P+l+e+lEt+a+en++++++++d++   a++ +++++ dk+lye++l+++ +  +l ++e+l++f+++La+rsa+Pri+a+yq++++s++s+  
      EEA20690.1  39 GPYLVELLETAAQENATSYFPLLDRI---ASGIFEDATHDKDLYESFLQVLIQdnHLqNKENLDSFKFALAIRSAAPRIQAHYQYYNTSVASTlg 130
                     59************************...79********************8889999********************************99988 PP

                     GGGSS.-SSEEEETTEEESSTT.------B...--SS-STS--TT---BS....--SEEEEEEE--SSTTSHHHHHHHHHHHHHTSEEEEEEE-- CS
  Thioredoxin_12  92 enekk.CkswvdvggelvcdveeleallkkekaassseqpellpfDhvypgskeasspvaILYgdlgskefkefhkkLkelakegkvkYvlRhvp 185
                      ++++ C  wv+++g+++c+++ le+++++    s +++p+ lpfD+ ++++   s+ +a+LY+d++s+ f+++h++Lk+la eg++ Y++R+ p
      EEA20690.1 131 TGQDAaCPVWVHMDGKQYCSST-LERAQQD---VSGDKDPRELPFDRTLGDT---SATPAVLYADIASPMFADYHRTLKALADEGQIAYRVRYRP 218
                     444444*************987.9**9999...999999**********544...5789************************************ PP

                     -TT CS
  Thioredoxin_12 186 psg 188
                     p +
      EEA20690.1 219 PHD 221
                     975 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 3.8
                     SSS-HHHHHHHHHHH CS
  Thioredoxin_12  13 akenedlFwefvdal 27 
                      ke+e+++w+ v++l
      EEA20690.1 777 QKEEEQAYWTQVQQL 791
                     58999*****99998 PP

>> Thioredoxin_15  Thioredoxin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0      0.96   2.4e+03     123     159 ..     324     360 ..     252     365 .. 0.67
   2 !    5.3   0.0    0.0066        17      53     154 ..     489     602 ..     466     609 .. 0.78
   3 !  148.1   0.0   1.3e-46   3.4e-43       9     212 ..     677     866 ..     669     867 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.96
                     H......HHHHHHHHHHHTT--TT-EEEEETTEEEEE CS
  Thioredoxin_15 123 naeeakdylkalqkflrvlglepgqnavilNGRvvgp 159
                     +a +a++ +++     r++gl  g n +++NG  + p
      EEA20690.1 324 AAYNASEEFSEEYMKNRQAGLPVGRNSMWINGLQIDP 360
                     3444555555555555689999999999999988876 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0066
                     HHH-TTEEEEEEE--S--SS-THHHHHHHHHTGGGGCT-SSHH.HHHHHHH..........................-------HH......HHH CS
  Thioredoxin_15  53 lksspgvRlgiihnpssdseasslissalsaalkklknleale.fleklleeet..............eellvsgmdkdafekelnaeeakdylk 132
                     +k+   vR g++  ++++++++++  ++++ +l++   l +l   le+ l +e               e  l ++ ++ +fe+ l++e+ ++ ++
      EEA20690.1 489 IKRLIPVRFGLVLTANTEESKAQA--KIAH-YLHQAYGLASLLqYLEASLASEKvshahkpsfeaaiaERSLRPDQESLSFEEILQSEALDATVA 580
                     555566999999999999765555..4444.5555544444443777766666678899999999999999999999999999999999999*** PP

                     HHHHHHHHTT--TT-EEEEETT CS
  Thioredoxin_15 133 alqkflrvlglepgqnavilNG 154
                       +k+l+ l l+  +   ++NG
      EEA20690.1 581 NTEKYLKRLALKGPSPPTLVNG 602
                     **********999888888888 PP

  == domain 3  score: 148.1 bits;  conditional E-value: 1.3e-46
                     THHHHTSS-EE---.S-TTT-EEEEEEE-TTSHHHHHHHHHHHHHHHH-TTEEEEEEE--S--SS-THHHHHHHHHTGGGGCT-SSHHHHHHHHH CS
  Thioredoxin_15   9 haslfeklpyless.sdklkpvtlwvvaDldseeGrkLLleAlkflksspgvRlgiihnpssdseasslissalsaalkklknlealefleklle 102
                     h+++++ l+ ++++ +     v+l++ +D+++e+G +LL +Alkf++++p+v+++ +hnp++d++  +  ss l+++l++ + ++ ++ l+++ +
      EEA20690.1 677 HNDFADILR-FPADrKHPAANVQLIITGDFNTEHGFALLISALKFHQTHPEVEIVPLHNPDTDEKVGEN-SSKLYELLRHPEPVDLDDVLAQIQS 769
                     555544444.54442558999******************************************996666.899999****************999 PP

                     ............-------HH......HHHHHHHHHHHTT--TT-EEEEETTEEEEEESSTTSS-HHHHHHHHHHHHHHTHHHHHHHHHHHT-TT CS
  Thioredoxin_15 103 eeteellvsgmdkdafekelnaeeakdylkalqkflrvlglepgqnavilNGRvvgpidedeefsaeDfelLesyerkkrikpvveaieelgles 197
                                  d  ++++++ee+++y++++q+++++lgl +g + +ilNGRvvgp++ + ef+++D+elL+sye ++r  p+ +a+++l++e 
      EEA20690.1 770 -------------DGSHQATQKEEEQAYWTQVQQLVTDLGLSAGNSTLILNGRVVGPLPPSVEFTEADLELLLSYETSQRLGPLSAALKDLDIEA 851
                     .............45555555689999******************************************************************** PP

                     S--SHHHHHHHHHHH CS
  Thioredoxin_15 198 kisdsdlvakvtSlv 212
                     ki++++ +ak+tSlv
      EEA20690.1 852 KIASPLNFAKLTSLV 866
                     *************98 PP

>> Thioredoxin_13  Thioredoxin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.5   0.0   9.9e-44   2.5e-40       5     132 ..     279     406 ..     275     411 .. 0.97
   2 ?   -3.4   0.0       3.3   8.5e+03      70      86 ..     419     435 ..     412     446 .. 0.82
   3 ?   -1.7   0.0         1   2.6e+03      63     107 ..     580     628 ..     566     636 .. 0.71
   4 ?   -0.7   0.0      0.49   1.2e+03      68      84 ..     791     811 ..     764     815 .. 0.69
   5 ?   -1.9   0.1       1.1   2.9e+03      33      50 ..    1378    1395 ..    1371    1400 .. 0.85

  Alignments for each domain:
  == domain 1  score: 137.5 bits;  conditional E-value: 9.9e-44
                     SS----SSGGTTHHHHHHHHHHHHSSHHHHHHHHHHTGGGGSTTCS-SSTTTTTTTTTHHHHHHS--TT--EEEETTEEE-GGG-SHHHHHHHHH CS
  Thioredoxin_13   5 dlkpLkawelqdLglqaaqlImssedpLkaLsdlsqnFPkyassLarvkvseelreeieanqerlvqpgqnalwlNGvaldesdidpfsLldlLr 99 
                     dlkpL+++e+++Lg+ aa+++++s dp+++L +lsq+FPky+ss+a++++see+ ee+ +n++  ++ g+n +w+NG+++d++++d++sLld Lr
      EEA20690.1 279 DLKPLSSSEVAKLGMSAASFVLDSADPFTTLVKLSQDFPKYSSSVAAYNASEEFSEEYMKNRQAGLPVGRNSMWINGLQIDPRQVDAYSLLDYLR 373
                     799******************************************************************************************** PP

                     HHHHHHHHHGGGS--HHHHHHHHT-HHHHHHHH CS
  Thioredoxin_13 100 kErkllnslkklglsseqaskllthpalakaks 132
                     +Erk + +++k+gls+++++++l+ pala+ + 
      EEA20690.1 374 RERKSIAEFQKIGLSASETIEILSYPALAEVQG 406
                     ****************************97765 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 3.3
                     --TT--EEEETTEEE-G CS
  Thioredoxin_13  70 vqpgqnalwlNGvalde 86 
                     +++g  ++wlN ++ d+
      EEA20690.1 419 IEGGGVVVWLNDLEKDK 435
                     7899999****997665 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 1
                     HHHHHHS....--TT--EEEETTEEE-GGG-SHHHHHHHHHHHHHHHHH CS
  Thioredoxin_13  63 eanqerl....vqpgqnalwlNGvaldesdidpfsLldlLrkErkllns 107
                      + +++l    +++ +   ++NG+a++  +  + +L   L ++ +++++
      EEA20690.1 580 ANTEKYLkrlaLKGPSPPTLVNGIAMSRGENYLQELPMQLSRDLQIIQQ 628
                     333333344458888889999*****99998888999999998888876 PP

  == domain 4  score: -0.7 bits;  conditional E-value: 0.49
                     HS....--TT--EEEETTEEE CS
  Thioredoxin_13  68 rl....vqpgqnalwlNGval 84 
                      +    +++g+++l+lNG+ +
      EEA20690.1 791 LVtdlgLSAGNSTLILNGRVV 811
                     225667899999999999876 PP

  == domain 5  score: -1.9 bits;  conditional E-value: 1.1
                      HHHHHHHHTGGGGSTTCS CS
  Thioredoxin_13   33 kaLsdlsqnFPkyassLa 50  
                      ++L +l q++P++ ++L 
      EEA20690.1 1378 ESLANLDQDLPNHMQTLI 1395
                      67999********99986 PP

>> UDP-g_GGTase  UDP-glucose:Glycoprotein Glucosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  134.6   0.0   5.3e-43   1.4e-39       1     109 []    1040    1145 ..    1040    1145 .. 0.95

  Alignments for each domain:
  == domain 1  score: 134.6 bits;  conditional E-value: 5.3e-43
                    EEE-EEESS----TT-EEEEE-SS-S-SEEEE--SGGGEEEEEE-SEEEEEEE-TTHHHHHEEEEE--SS-S--TT----EEEE-STT-EEE--E CS
  UDP-g_GGTase    1 eGhardettkspprGlqleLgtekkksvaDTivmanlGYfQlkanPGvwklelregrssdiyeiesvgaeglsspkdegkevvltsfegktlypr 95  
                    eGh+ d+t +spprG+ql L+tek + +aDTivmanlGYfQ+ka+PG+wk+el+egrs+di++++s+g  + +s++  ++ev+l sf+gktl+p+
    EEA20690.1 1040 EGHSSDTTLRSPPRGVQLLLETEKGSFFADTIVMANLGYFQFKAQPGFWKIELKEGRSRDIFQLDSIGGGQ-QSSG--TNEVALLSFQGKTLFPH 1131
                    8******************************************************************8887.4444..579************** PP

                    EEE-TT----TTS- CS
  UDP-g_GGTase   96 vkrkpgkekedvle 109 
                    ++rkpg+e+e+vle
    EEA20690.1 1132 LSRKPGQEQEEVLE 1145
                    ***********986 PP

>> Glyco_transf_8  Glycosyl transferase family 8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0     1e-06    0.0026      16     133 ..    1205    1313 ..    1192    1347 .. 0.74

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 1e-06
  Glyco_transf_8   16 vviksllknakepawfalnfhiltaeievenleklnklassykevlellesdkksledfesklklrspkylsllnylRlylpelfpkldkily 108 
                      +++ s++kn+++    +++f  +++ + +  ++ l  la++y   +e++  +   + +    + +++ + + +  ++  +l+ l  +ldk+++
      EEA20690.1 1205 IMMVSVMKNTNH----SVKFWFIEQFLSPSFKSFLPHLAEEYGFTYEMVTYKWPHWLR---GQREKQREIWGYKILFLDVLFPL--SLDKVIF 1288
                      566777777774....777777777777777777777777777776665555544443...35666666666666655555555..******* PP

  Glyco_transf_8  109 lDaDvvvqgdlseLwdldlkgkvla 133 
                      +DaD +v +d+ +L  ldl+g   +
      EEA20690.1 1289 VDADQIVRTDMYDLVTLDLEGAPYG 1313
                      *******************987665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1490 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       502  (0.0279993); expected 358.6 (0.02)
Passed bias filter:                      427  (0.0238162); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.90u 0.30s 00:00:01.20 Elapsed: 00:00:00.46
# Mc/sec: 9696.17
//
Query:       EEA20691.1  [L=691]
Description: MYB DNA-binding domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.2e-13   51.1   8.7      2e-06   27.9   0.3    3.5  4  Myb_DNA-binding  Myb-like DNA-binding domain
    4.4e-10   39.7   8.7    1.5e-08   34.8   0.7    3.1  3  Myb_DNA-bind_6   Myb-like DNA-binding domain
  ------ inclusion threshold ------
        1.3    9.4   4.7        1.5    9.2   0.8    2.7  2  Myb_DNA-bind_4   Myb/SANT-like DNA-binding domain


Domain annotation for each model (and alignments):
>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.1      0.25   1.5e+03       2      14 ..     198     210 ..     197     211 .. 0.85
   2 ?   -2.4   0.1      0.97   5.8e+03      23      43 ..     254     274 ..     250     277 .. 0.77
   3 !   27.9   0.3   3.4e-10     2e-06       3      44 ..     285     325 ..     283     326 .. 0.96
   4 !   26.7   0.1   8.1e-10   4.8e-06       2      45 ..     336     402 ..     335     403 .. 0.91

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.25
                      SSSBHHHHHHHHH CS
  Myb_DNA-binding   2 gkWteeEdelLle 14 
                      g +++eE e L++
       EEA20691.1 198 GLFSPEEIETLEQ 210
                      779******9986 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.97
                      HHHHHHHHTSS-HHHHHHHHH CS
  Myb_DNA-binding  23 WkkIaerlggRtekqcrsrwr 43 
                      W +I   ++ R  k++  + r
       EEA20691.1 254 WQSIYGQIPDRDQKSINRFCR 274
                      999999999999999855544 PP

  == domain 3  score: 27.9 bits;  conditional E-value: 3.4e-10
                      SSBHHHHHHHHHHHHHHTTCHHHHHHHHTSS-HHHHHHHHHH CS
  Myb_DNA-binding   3 kWteeEdelLleavkkhGnrWkkIaerlggRtekqcrsrwrn 44 
                      +Wt+ +d+ L+++++ +G +W+ Ia+ +  Rt  ++  rw+n
       EEA20691.1 285 QWTTADDDELERLHHALGPKWAQIARDM-ERTYDDVVQRWKN 325
                      7***************************.6**********98 PP

  == domain 4  score: 26.7 bits;  conditional E-value: 8.1e-10
                      SSSBHHHHHHHHHHHHH............HTTC..........HHHHHHHHT.SS-HHHHHHHHHHH CS
  Myb_DNA-binding   2 gkWteeEdelLleavkk............hGnr..........WkkIaerlg.gRtekqcrsrwrny 45 
                      g+W  +E ++L+e +++             G++          W +I++r++ +R++ q+ ++wr++
       EEA20691.1 336 GPWDDDEINKLIECLEEtrkihltmekvdIGKDiydlpdefisWGAISDRFQhTRSRQQIADKWRKV 402
                      89**********************9999966667777779*************************97 PP

>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.1       1.1   6.8e+03      20      41 ..     254     274 ..     250     283 .. 0.67
   2 !   34.8   0.7   2.4e-12   1.5e-08       1      60 []     286     346 ..     286     346 .. 0.96
   3 !    9.1   0.1   0.00025       1.5      19      43 ..     378     402 ..     350     420 .. 0.76

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 1.1
  Myb_DNA-bind_6  20 WknIaealnrRtpkqcfdrwkn 41 
                     W +I  +++ R++k++ +r+++
      EEA20691.1 254 WQSIYGQIPDRDQKSI-NRFCR 274
                     8888888888888886.35555 PP

  == domain 2  score: 34.8 bits;  conditional E-value: 2.4e-12
  Myb_DNA-bind_6   1 WteeEdeiLlklvekygndWknIaealnrRtpkqcfdrwkn..kLrpkisrkkwskeedirL 60 
                     Wt ++d++L +l+ + g +W +Ia+ +  Rt  ++ +rwkn  ++r+ ++ ++w + e+ +L
      EEA20691.1 286 WTTADDDELERLHHALGPKWAQIARDME-RTYDDVVQRWKNkvEHRHTMKLGPWDDDEINKL 346
                     ****************************.************8888999********998776 PP

  == domain 3  score: 9.1 bits;  conditional E-value: 0.00025
  Myb_DNA-bind_6  19 dWknIaeal.nrRtpkqcfdrwknkL 43 
                      W  I++ + + R+ +q+ d+w++ +
      EEA20691.1 378 SWGAISDRFqHTRSRQQIADKWRK-V 402
                     799******669***********9.3 PP

>> Myb_DNA-bind_4  Myb/SANT-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.2      0.21   1.3e+03      34      47 ..     303     315 ..     284     331 .. 0.63
   2 ?    9.2   0.8   0.00025       1.5       3      65 ..     337     404 ..     336     417 .. 0.71

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.21
                     HHHHHHHHHHHHHH CS
  Myb_DNA-bind_4  34 kklWeevaeamaer 47 
                       +W ++a+ m++ 
      EEA20691.1 303 P-KWAQIARDMERT 315
                     4.799999999753 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00025
                     SS-HHHHHHHHHHHHH...HHHHHHH........SS--HHHHHHHHHHHHHHC----HHHHHHHHHHHHH CS
  Myb_DNA-bind_4   3 kWteeetklLieawge.rilelrfqe......rgkkrnkklWeevaeamaergykrspeqCkeKienLkk 65 
                      W ++e++ Lie  +e r  +l +++             + + +  +   + +++rs +q+ +K++++k+
      EEA20691.1 337 PWDDDEINKLIECLEEtRKIHLTMEKvdigkdI--YDLPDEFISWGAISDRFQHTRSRQQIADKWRKVKR 404
                     599***********9977677766656666431..222333444444445667899**********9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (691 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1304  (0.0727313); expected 358.6 (0.02)
Passed bias filter:                      474  (0.0264376); expected 358.6 (0.02)
Passed Vit filter:                       127  (0.0070835); expected 17.9 (0.001)
Passed Fwd filter:                        73  (0.00407162); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 1.41u 0.35s 00:00:01.75 Elapsed: 00:00:00.53
# Mc/sec: 3927.22
//
Query:       EEA20692.1  [L=279]
Description: exosome complex exonuclease Rrp40, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.5e-17   62.9   0.0    5.9e-17   61.8   0.0    1.7  1  KH_6      KH domain
    7.8e-07   28.9   0.5    2.3e-06   27.5   0.5    1.9  1  Rrp40_N   Exosome complex exonuclease Rrp40 N-terminal domain


Domain annotation for each model (and alignments):
>> KH_6  KH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.8   0.0   6.5e-21   5.9e-17       1      43 [.     175     234 ..     175     237 .. 0.96

  Alignments for each domain:
  == domain 1  score: 61.8 bits;  conditional E-value: 6.5e-21
        KH_6   1 GmlfeVslslvrRll.............nhvLeeLgka....gpfeiavGlNGriWvkse 43 
                 Gmlf++s++l+ Rl+             +++LeeLgk+    g+feiavG+NG++Wv+++
  EEA20692.1 175 GMLFDISTGLAARLMkassssssaeatsVVILEELGKKfeskGGFEIAVGRNGKVWVDCS 234
                 9***********************************99999999**************97 PP

>> Rrp40_N  Exosome complex exonuclease Rrp40 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.5   0.5   2.5e-10   2.3e-06       3      44 ..      22      76 ..      19      80 .. 0.75

  Alignments for each domain:
  == domain 1  score: 27.5 bits;  conditional E-value: 2.5e-10
     Rrp40_N  3 psssklkLGPGLrhtP......plst.........liatraGiLhtkpkkqalwiEs 44
                +s+++l+LGPGLr +       +  t         + at+aGiL+ +p+++++ + +
  EEA20692.1 22 ASTTPLRLGPGLRLLQrqsqntN--TntnpppahvIQATQAGILSIDPNRKSVSVQT 76
                46788*******77775445441..1345666667*****************99865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (279 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       361  (0.020135); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 1844.49
//
Query:       EEA20693.1  [L=565]
Description: Hsp70 chaperone (BiP), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-78  264.3   3.0    1.7e-78  264.3   3.0    1.7  2  HSP70     Hsp70 protein
    3.4e-07   29.4   0.5    5.8e-07   28.6   0.5    1.3  1  MreB_Mbl  MreB/Mbl protein
  ------ inclusion threshold ------
      0.025   13.6   0.1        3.9    6.4   0.0    2.9  3  PilM_2    Type IV pilus assembly protein PilM;
      0.089   13.2   1.5       0.25   11.7   1.5    1.8  1  DUF3221   Protein of unknown function (DUF3221)
       0.77    9.6   2.8        1.5    8.6   2.8    1.4  1  Vpu       Vpu protein


Domain annotation for each model (and alignments):
>> HSP70  Hsp70 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  264.3   3.0   4.7e-82   1.7e-78       1     442 [.      12     472 ..      12     484 .. 0.86
   2 ?   -1.6   0.2      0.16   5.7e+02     447     486 ..     514     549 ..     479     563 .. 0.63

  Alignments for each domain:
  == domain 1  score: 264.3 bits;  conditional E-value: 4.7e-82
                 EEEEEEXSSEEEEEEEE.TTEEEEEXXTTSXSSEESEEEEXTTSEEETHHHHHCTTTTGGGEEEXGGGTTTXBTTSHHHH.HHHTTXSSEEEEETTSBE CS
       HSP70   1 viGiDLGttnsvvavme.ggkievianeegnrttPsvvaFtkkerlvGeaAkrqavtnpkntvfsvKrliGrkfsdpevq.keikelpykvvkkengka 97 
                 +iGi  G+ +s +a    +gk+evianeeg+r  Ps++++ + e   G++Ak q ++n+kntv+ ++ ++G++f+  + + ++ +  p +v ++     
  EEA20693.1  12 AIGISFGNSSSSIAFTGpDGKAEVIANEEGDRQIPSILSYVESEEFHGTQAKAQLIRNSKNTVAYFRDYLGKDFKSIDPTpAHQSAHPQQVDST--VAF 108
                 59************8753899*****************************************************98433213344445555544..445 PP

                 EEEEEETTE..EEEHHHHHHHHHHHHHHHHHHHHTSBEEEEEEEEXTTXXHHHHHHHHHHHHHTTXEEEEEEEHHHHHHHHHHTCCSS..SCEEEEEEE CS
       HSP70  98 vveveaage..kftpeqisamvLkklketaeaylgkkvtdavitvPaYfndaqRqatkdAgkiAGLnvlRivNepTAaalaYGldkkd..kernvlvyD 192
                 +++ + a+   + t ++i+++ L++lk+ a ++lgk+v+ avitvP+ f daqR+    A+k A ++vl ++ ep Aa laY    +   +++ v+v D
  EEA20693.1 109 TIQDTDAETpsTVTVSEITTRHLRRLKQSATDFLGKTVNAAVITVPTNFSDAQREVLVAAAKNADIEVLQLIHEPVAALLAYDARPDAviEDKLVVVAD 207
                 555554444779**********************************************************************998887999******** PP

                 EXSSXEEEEEEEEETTEEEEEEEEEETTXSHHHHHHHHHHHHHHHHHHHHSXXGGGSHHHHHHHHHHHHHHHHHTTTSSCSEEEEEEEEEETTTEEEEE CS
       HSP70 193 lGggtfdvSilelekGvfevkaTagDthlGGedfDealvehlveefkkkegidlskdkkalqrlkeaaekaKkeLSsskqteinleietvdedgkdlse 291
                 +Gg   dv +++   G++ ++aT  D +lGG + D++++eh+++ef kk++ d ++d + l +lk + e  Kk+LS    t+++l+ie++ + g d+ +
  EEA20693.1 208 FGGIRSDVAVVASRGGMYTILATVHDYELGGANLDQVVIEHFAKEFIKKHKADPREDVRGLAKLKLESEATKKALSI--GTNATLSIESLVN-GIDYGS 303
                 *****************************************************************************..9************.****** PP

                 EEEHHHHHHHHHHHHHHTHHHHHHHHHHCTEEGGGCSEEEEESGGGGSHHHHHHHHHHTT...C..HHB...SSSHTTTHHHHHHHHHHHHHCTCGCSH CS
       HSP70 292 klsRakfeelvedllertlepvekalkdaklkkeeidevvlvGGstRiPkvqelvkelfg...k..eps...ktvnpDeavaiGAAvqagvlsgeeevk 382
                 +++R ++e l  +++++ +  +e+a+k a+l++ +idev+l GG++  Pk+  l++++f    k   ps   +++np e  a+GAA qa + +  ++++
  EEA20693.1 304 TINRTRYELLSGKIFSQFTGLIESAVKKAGLDVLDIDEVILAGGTSHTPKIARLLESIFPettKvlAPSttpSAINPSELSARGAAYQASLIQE-FDTE 401
                 *********************************************************99732222224422246****************9998.8888 PP

                 CCE.....EEEBES.S..-EEEEET..TTE..EEEEESTTCBSSEEEEEEEEESSTTSSSEEEEEEESSSSB CS
       HSP70 383 dll.....llDvtp.L..slgietl..ggv..mtkliernttiptkksqvfstaadnqtaveievlqgerel 442
                 d+      +  vtp L  ++g+++   +g+  +  l +  t++p+++   +++  ++  +v i++++gere+
  EEA20693.1 402 DIEqsihpMVTVTPhLskTIGVQVVsaDGSsdFAPLVNADTALPARRVAQYTVP-KEGGDVLIRISEGEREI 472
                 875333336677775422355544322333357888999999999988776554.45568999999999986 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.16
                 EEEEEEEEECESSCSTTCSEEEEEEEEETTSCEEEEEEET CS
       HSP70 447 kllgsfeldgippaprGvpqieVtfdidanGiltvsakdk 486
                 k +++ +++g+++      ++eVt++i+ +  l+++a++ 
  EEA20693.1 514 KPIAEAAVKGVKA----GGKVEVTININSDLGLQITAREV 549
                 5555555555552....24677777777776667777665 PP

>> MreB_Mbl  MreB/Mbl protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.6   0.5   1.6e-10   5.8e-07      72     295 ..     125     360 ..     118     383 .. 0.67

  Alignments for each domain:
  == domain 1  score: 28.6 bits;  conditional E-value: 1.6e-10
                 HHHHHHHHHHHHHHHTSS-SS--EEEEEE-SS--HHHHHHHHHHHHHTT-SEEEEEEHHHHHHHHTT-...-TTSSS-EEEEEE-SS-EEEEEE.ETTE CS
    MreB_Mbl  72 evaeellkyfikkvkkkkslskprvvicvPsgiteverrAvkeaakkaGarevllieeplaAAiGagl...pveepsgnmvvdiGggttevavi.slgg 166
                 e++ + l+++ + +++    + +  vi+vP++ ++ +r+ +  aak+a  +  +li ep+aA +  +     v e +  +v d Gg  ++vav+ s gg
  EEA20693.1 125 EITTRHLRRLKQSATDFLGKTVNAAVITVPTNFSDAQREVLVAAAKNADIEVLQLIHEPVAALLAYDArpdAVIEDKLVVVADFGGIRSDVAVVaSRGG 223
                 6777777887777777666777889*************************************99887633348899999999**********9945567 PP

                 E....EEEEEES-SHHHHHHHHHHHHHHHHSEE--HHHHHHH....HHHH-BSS--HHHH...EEEEEEEETTTTCEEEEEEEHHHHHHHHHHHHHHHH CS
    MreB_Mbl 167 i....vtsksvrvaGdeldeaiikyirkkynlliGertaeki....kieigsavkeeeee...kmeikGrdlvtglpkevevsseevrealkepvsaiv 254
                 +     t +   ++G +ld+ +i++  k++         e++    k+++ s ++++  +   + +++   lv+g+    +++ ++ +    + +s+ +
  EEA20693.1 224 MytilATVHDYELGGANLDQVVIEHFAKEFIKKHKADPREDVrglaKLKLESEATKKALSigtNATLSIESLVNGIDYGSTINRTRYELLSGKIFSQFT 322
                 6211134566789***********999888555544444554111133333333333322333344444455556655556655555555555555555 PP

                 HHHHHHHHTS-HHHHHHHHH.H-EEEESGGGGSBTHHHHHHH CS
    MreB_Mbl 255 eavkevLektppeLaadivd.rgivltGGgallkgldkllse 295
                   ++++ +k+  +    ++d   ++l+GG++    + +ll++
  EEA20693.1 323 GLIESAVKKAGLD----VLDiDEVILAGGTSHTPKIARLLES 360
                 5555555555443....3332346777777777777766665 PP

>> PilM_2  Type IV pilus assembly protein PilM;
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0     0.084     3e+02      52      96 ..     124     168 ..     102     184 .. 0.76
   2 ?    2.9   0.0     0.012        45     170     229 ..     190     255 ..     169     265 .. 0.79
   3 ?    6.4   0.0    0.0011       3.9     274     329 ..     338     390 ..     332     394 .. 0.81

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.084
      PilM_2  52 krvvkklktrvkevaiavpgsavitkkialdadLteeeleaqvel 96 
                   ++ +   r+k+ a    g++v   +i++++++++++ e+ v +
  EEA20693.1 124 SEITTRHLRRLKQSATDFLGKTVNAAVITVPTNFSDAQREVLVAA 168
                 455555666778888888888899999999999999988887765 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.012
      PilM_2 170 asqlpdkg.kekvvaivdigasrttlsvlrdgkivYt.....reqafGgeqltqeivrrYglslee 229
                 +++ pd++ ++k+v ++d g  r+ ++v+     +Yt      + ++Gg++l q +++++  ++ +
  EEA20693.1 190 YDARPDAViEDKLVVVADFGGIRSDVAVVASRGGMYTilatvHDYELGGANLDQVVIEHFAKEFIK 255
                 4555665426789*******************999986666679999**********999877655 PP

  == domain 3  score: 6.4 bits;  conditional E-value: 0.0011
      PilM_2 274 kvdkilLaGGtaslpgleelleeelgisttvanpfaemelsekvrakklardapsy 329
                  +d+++LaGGt+ +p +++lle     +t+v+ p++     + ++ ++l++ +++y
  EEA20693.1 338 DIDEVILAGGTSHTPKIARLLESIFPETTKVLAPSTTP---SAINPSELSARGAAY 390
                 68**********************99999999998754...445556666666655 PP

>> DUF3221  Protein of unknown function (DUF3221)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   1.5     7e-05      0.25      17      62 ..     487     535 ..     482     540 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 7e-05
     DUF3221  17 eiekeeaenlseeeiekykgeaiwv...lidsdkvsnlevGqkVrVwfd 62 
                 e+ +e+++  s+ee e+++ e +w     i    v++++ G kV+V+++
  EEA20693.1 487 EEAEEDSDFDSDEEEEEETREVVWKstkPIAEAAVKGVKAGGKVEVTIN 535
                 56677888888888999********99999*****************98 PP

>> Vpu  Vpu protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   2.8   0.00043       1.5      40      68 ..     480     508 ..     466     517 .. 0.84

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00043
         Vpu  40 erlikrireraedSgnESdGeeeeelakL 68 
                 +  +++  e +edS+  Sd+eeeee ++ 
  EEA20693.1 480 QSKAEKTEEAEEDSDFDSDEEEEEETREV 508
                 56788999****************87765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (565 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       874  (0.0487478); expected 358.6 (0.02)
Passed bias filter:                      558  (0.0311228); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.67u 0.31s 00:00:00.98 Elapsed: 00:00:00.45
# Mc/sec: 3754.04
//
Query:       EEA20694.1  [L=251]
Description: actin cortical patch protein Sur7, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.6e-41  141.6   7.7      3e-41  141.4   7.7    1.0  1  SUR7      SUR7/PalI family
    1.7e-05   24.4   0.2      3e-05   23.6   0.2    1.4  1  Clc-like  Clc-like
    0.00086   19.2   6.3      0.005   16.7   3.6    2.1  2  Amastin   Amastin surface glycoprotein


Domain annotation for each model (and alignments):
>> SUR7  SUR7/PalI family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  141.4   7.7     5e-45     3e-41       2     211 ..       9     203 ..       8     204 .. 0.96

  Alignments for each domain:
  == domain 1  score: 141.4 bits;  conditional E-value: 5e-45
        SUR7   2 rlillflslaalilllfailgsiknstpltsiylskfdlsgldlaqigladvysfgvwgyCdnsdvnytkCskpkagypfdp..leelnsesngkvdlP 98 
                  +++lf++++al+l+ +++lg+ +n++pl++iy++++++s++++a    ++++++++w++C + ++++++C  +++++pfdp   +++++++n    +P
  EEA20694.1   9 GILALFFTAGALVLMYLTLLGGANNHVPLNEIYFLQANTSNIPGA----PSISRWTFWNIC-SVSDGKSQCGTTHPDFPFDPpsSQNFGTDTN----IP 98 
                 5899************************************99999....************.8889999************8755********....** PP

        SUR7  99 snlrktlsklnnltkalfilhiialvlsfislvvgllaicvspdnsrllsflnlllsvlsflatllaalldtllfvfvrkkinlkefgikaslglkfla 197
                  ++  t+++ + l++++f +++ial++ ++sl++g++a c      r++s l  ll  ++ ++ +++  l+t++fv  r+++  ++ g +a+lg k ++
  EEA20694.1  99 AAFIGTRHY-YLLSRFMFPFMLIALFFATLSLFLGVVAPC-----TRIGSYLSGLLGSIAWVFQVITTTLMTACFVQGRHHF--NSNGQSAKLGPKAFG 189
                 ********5.8*****************************.....9************************************..9************** PP

        SUR7 198 faWlalaaallvvi 211
                 f+W+al ++ l+++
  EEA20694.1 190 FMWTALTLLTLSSV 203
                 ********999986 PP

>> Clc-like  Clc-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.6   0.2     5e-09     3e-05      87     157 ..      94     168 ..      62     177 .. 0.83

  Alignments for each domain:
  == domain 1  score: 23.6 bits;  conditional E-value: 5e-09
    Clc-like  87 dedsavgelethkFygWhkavlilllislllaalsllsgicasvsssea....ilftillvlaallalvadiiFf 157
                 d + ++  + t ++y   ++++ ++li+l++a+lsl+ g++a++++  +    +l +i  v+  +++++  + F+
  EEA20694.1  94 DTNIPAAFIGTRHYYLLSRFMFPFMLIALFFATLSLFLGVVAPCTRIGSylsgLLGSIAWVFQVITTTLMTACFV 168
                 66777778889999********************************99988888888888888888888877776 PP

>> Amastin  Amastin surface glycoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0     0.012        69      68     121 ..       8      62 ..       5      93 .. 0.76
   2 !   16.7   3.6   8.3e-07     0.005      68     147 ..     117     197 ..      93     205 .. 0.86

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.012
     Amastin  68 fsiisilvlaaalllsvllllccsslkwvclllnivsvvtllivwalmvavyy.k 121
                 f i++++++a al+l  l ll+ ++  + +  + ++ + t+ i+ a  ++ ++  
  EEA20694.1   8 FGILALFFTAGALVLMYLTLLGGANNHVPLNEIYFLQANTSNIPGAPSISRWTfW 62 
                 889**************99999877777777777777777777777777777663 PP

  == domain 2  score: 16.7 bits;  conditional E-value: 8.3e-07
     Amastin  68 fsiisilvlaaalllsvllllccsslkwvclllnivsvvtllivwalmvavyykrfCd.alksttakyga.GFgLlvvawll 147
                 f +i++++ +++l+l+v++ +  ++  ++  ll+ +++v+++i++ lm+a++ + +   + + ++ak+g+ +Fg + +a  l
  EEA20694.1 117 FMLIALFFATLSLFLGVVAPCT-RIGSYLSGLLGSIAWVFQVITTTLMTACFVQGRHHfNSNGQSAKLGPkAFGFMWTALTL 197
                 889******************9.******************************76665478888888987677777777655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (251 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       669  (0.0373138); expected 358.6 (0.02)
Passed bias filter:                      330  (0.0184059); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 1638.14
//
Query:       EEA20695.1  [L=229]
Description: actin cortical patch protein Sur7, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.5e-37  128.6   4.4    2.9e-37  128.4   4.4    1.0  1  SUR7      SUR7/PalI family
    1.6e-05   24.5   0.2    2.4e-05   23.9   0.2    1.3  1  Clc-like  Clc-like
     0.0016   18.3   2.9     0.0025   17.7   2.9    1.3  1  Amastin   Amastin surface glycoprotein


Domain annotation for each model (and alignments):
>> SUR7  SUR7/PalI family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  128.4   4.4   4.9e-41   2.9e-37      17     211 ..       2     181 ..       1     182 [. 0.96

  Alignments for each domain:
  == domain 1  score: 128.4 bits;  conditional E-value: 4.9e-41
        SUR7  17 lfailgsiknstpltsiylskfdlsgldlaqigladvysfgvwgyCdnsdvnytkCskpkagypfdp..leelnsesngkvdlPsnlrktlsklnnltk 113
                  +++lg+ +n++pl++iy++++++s++++a    ++++++++w++C + ++++++C  +++++pfdp   +++++++n    +P ++  t+++ + l++
  EEA20695.1   2 YLTLLGGANNHVPLNEIYFLQANTSNIPGA----PSISRWTFWNIC-SVSDGKSQCGTTHPDFPFDPpsSQNFGTDTN----IPAAFIGTRHY-YLLSR 90 
                 5789*********************99999....************.8889999************8755********....**********5.8**** PP

        SUR7 114 alfilhiialvlsfislvvgllaicvspdnsrllsflnlllsvlsflatllaalldtllfvfvrkkinlkefgikaslglkflafaWlalaaallvvi 211
                 ++f +++ial++ ++sl++g++a c      r++s l  ll  ++ ++ +++  l+t++fv  r+++  ++ g +a+lg k ++f+W+al ++ l+++
  EEA20695.1  91 FMFPFMLIALFFATLSLFLGVVAPC-----TRIGSYLSGLLGSIAWVFQVITTTLMTACFVQGRHHF--NSNGQSAKLGPKAFGFMWTALTLLTLSSV 181
                 *************************.....9************************************..9**********************999986 PP

>> Clc-like  Clc-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.2   4.1e-09   2.4e-05      87     157 ..      72     146 ..      40     155 .. 0.83

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 4.1e-09
    Clc-like  87 dedsavgelethkFygWhkavlilllislllaalsllsgicasvsssea....ilftillvlaallalvadiiFf 157
                 d + ++  + t ++y   ++++ ++li+l++a+lsl+ g++a++++  +    +l +i  v+  +++++  + F+
  EEA20695.1  72 DTNIPAAFIGTRHYYLLSRFMFPFMLIALFFATLSLFLGVVAPCTRIGSylsgLLGSIAWVFQVITTTLMTACFV 146
                 66777778889999********************************99988888888888888888888877776 PP

>> Amastin  Amastin surface glycoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   2.9   4.2e-07    0.0025      68     147 ..      95     175 ..      72     183 .. 0.86

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 4.2e-07
     Amastin  68 fsiisilvlaaalllsvllllccsslkwvclllnivsvvtllivwalmvavyykrfCd.alksttakyga.GFgLlvvawll 147
                 f +i++++ +++l+l+v++ +  ++  ++  ll+ +++v+++i++ lm+a++ + +   + + ++ak+g+ +Fg + +a  l
  EEA20695.1  95 FMLIALFFATLSLFLGVVAPCT-RIGSYLSGLLGSIAWVFQVITTTLMTACFVQGRHHfNSNGQSAKLGPkAFGFMWTALTL 175
                 889******************9.******************************76665478888888987677777777655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (229 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       579  (0.032294); expected 358.6 (0.02)
Passed bias filter:                      285  (0.015896); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 1585.25
//
Query:       EEA20696.1  [L=308]
Description: hypothetical protein PMAA_045210 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.2e-84  282.2   0.0    4.8e-84  282.0   0.0    1.0  1  Rogdi_lz  Rogdi leucine zipper containing protein


Domain annotation for each model (and alignments):
>> Rogdi_lz  Rogdi leucine zipper containing protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  282.0   0.0   2.7e-88   4.8e-84       1     267 [.      25     294 ..      25     295 .. 0.96

  Alignments for each domain:
  == domain 1  score: 282.0 bits;  conditional E-value: 2.7e-88
    Rogdi_lz   1 EleWLlkeelketlpqlkegLeeClallapedpgstLvlSssrsesvKGvvtRvGtrivkgdislrlrtlpk........ltlklnptkp.ivleqLtd 90 
                 EleWLl  +l+e+l +l++gL+eC+ llap++pgstLv+Ss rsesvKG+vtR Gtri+kgdi+lrl +lp+        l++++ p++p +vl qL++
  EEA20696.1  25 ELEWLL-ASLQESLAALRDGLQECAGLLAPKEPGSTLVVSSVRSESVKGFVTRIGTRIIKGDIQLRLTSLPPprgahstrLSVSSVPGAPeLVLDQLAA 122
                 9*****.***********************************************************************9999999998889******** PP

    Rogdi_lz  91 lrtlltqaldlLdltlktgdelsksaqflssqLrllleslseAkalLkgppepelafpangwttesaa.shfePplppnlsldlyiqeaelvldlrvLe 188
                 +r+l++q ld++d+++ tgd+l+  a+f+s qLrll+e++seAk +Lkg +e++    +  w+++sa+ + f+Pplpp ls++l+i +a+lvl lr+Le
  EEA20696.1 123 VRNLVNQGLDVIDVSTFTGDPLN--ASFISGQLRLLYEHMSEAKLALKGGAETS----K--WWEKSADsRVFDPPLPPYLSFHLTIVDAALVLHLRTLE 213
                 ***********************..99*************************44....4..************************************** PP

    Rogdi_lz 189 pvtakpwsei.stsfgdkladalgtarrlehdeaeevfk.kgeeVmvrekvrVesaDPsLislsakLgalehllaqarrnL 267
                 p +a++ s+   +++g +l+d l + r   hde ++vf+ +geeV+v+ek+rVe++DPsLi+++akL+aleh++ ++r +L
  EEA20696.1 214 PSSANQASTAfGSEIGFALRDRLFGPRLPSHDEQNNVFEwQGEEVKVKEKIRVETQDPSLIAVMAKLSALEHEVLKCRASL 294
                 ******876555577777777779***************999***********************************9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (308 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       442  (0.0246528); expected 358.6 (0.02)
Passed bias filter:                      382  (0.0213063); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2148.53
//
Query:       EEA20697.1  [L=860]
Description: 37S ribosomal protein Rsm22 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-30  105.8   0.0    2.6e-29  102.4   0.0    2.7  1  Rsm22     Mitochondrial small ribosomal subunit Rsm22


Domain annotation for each model (and alignments):
>> Rsm22  Mitochondrial small ribosomal subunit Rsm22
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.4   0.0   1.4e-33   2.6e-29       3     274 ..     364     745 ..     362     746 .. 0.79

  Alignments for each domain:
  == domain 1  score: 102.4 bits;  conditional E-value: 1.4e-33
       Rsm22   3 esiaYalarlpatyavlrrvLdelaerv.pdflPk........slldvgegpgtalwaaselweeleevlvidaseel.leiskelaadapelkeaalr 91 
                 e+ aY++a  p+ ya   +vL e+++r   ++l           +ldvg g g++++a  ++ +   e +v d  +++   ++k  + +   + +   r
  EEA20697.1 364 EANAYLAALYPGIYASTLSVLVEVRKRLgSKWLRDlmmqetgpRVLDVG-GSGAGILAWRDVLRAEYETMVPDHPKDApIPMGKSTVLAGSDALQM--R 459
                 6677777777777777777777777765233433211111111356665.5677788888887744444444444333144555444333333333..3 PP

       Rsm22  92 rsvirealeleea.........................dLviisyvLleled.esreklvknlWakask...ilvivEeGtpaGfrrvleaReal.... 157
                  s++ +  ++ +                          d++i  ++Lle+ +   r++ vknlW  ++    +l+++E+G ++Gf+ +  aRe+l    
  EEA20697.1 460 ASILLDNTTFLPRlpdyvhvrdsstlederappkrkqfDVIIAPHTLLEIDEdYLRKQHVKNLWTMLNPkggVLILLEKGRQKGFEAIAGAREMLlekh 558
                 44555555555555556666666777777888999999************997789*********99866779************************** PP

       Rsm22 158 .....................kaagfhivAPCPHeaaCPlvate.......dwChFsqrvaRls.lhrlaksasvpvedekfsyvakerqprasa.... 223
                                      +++ + i+APC  + +CP+ + +       d+ChF qr+ R   l+r++  ++ ++ed  fsy+a +r+ +  +    
  EEA20697.1 559 isspgsteyesltesgdqgsiRKEAGMIIAPCTNHGKCPMYHIHghakgrgDYCHFEQRYIRPPfLQRIVGAKDRNHEDVEFSYIAVQRGVDLRQtesi 657
                 *****************9997777889************976434456689**********975378999999***********999999887777789 PP

       Rsm22 224 ....................................aaRvvrptkvrskkvlidlCsedetlqrlvvtKrkG.eaykaArkaeWGDrl 274
                                                      +R v p+++r ++v+ dlC+ +++++r +v ++   +ay+ Arka+WGD++
  EEA20697.1 658 vqgkaatdaafegyedsvsteegetaqaftavnplsLPRTVLPPMKRRGHVIFDLCTPEGKIERWTVPRSFSrQAYHDARKARWGDLW 745
                 *********************************************************************6554**************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (860 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       453  (0.0252663); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.64u 0.29s 00:00:00.93 Elapsed: 00:00:00.42
# Mc/sec: 6141.73
//
Query:       EEA20698.1  [L=168]
Description: mitotic spindle biogenesis protein Spc19, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      4e-51  173.0   4.5    5.4e-51  172.6   4.5    1.2  1  DASH_Spc19    Spc19
      0.002   18.2   0.0     0.0029   17.6   0.0    1.3  1  Mur_ligase_M  Mur ligase middle domain
  ------ inclusion threshold ------
       0.91    9.7   7.2         12    6.1   0.3    3.0  3  COG5          Golgi transport complex subunit 5


Domain annotation for each model (and alignments):
>> DASH_Spc19  Spc19
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  172.6   4.5     9e-55   5.4e-51       1     157 []       5     150 ..       5     150 .. 0.89

  Alignments for each domain:
  == domain 1  score: 172.6 bits;  conditional E-value: 9e-55
                 .HHHHHHHHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHH-------TTTHHHHHHHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  DASH_Spc19   1 LencvsSLrssvslLqssietLdsgvsdfprlkkvLkttrvFeLipesdleaakaslaeeiePqieellekaekeleklerreetLkaklelqegrlsn 99 
                 L+++v+SLr+s++lL+ssi++Ldsgv+dfprl+kvL+ttr+FeL+pe++l++a++sl +ei+P+i++ll+ + +++e+l+rre++L+ak++lqegrls+
  EEA20698.1   5 LSSSVASLRTSLHLLESSIDILDSGVNDFPRLSKVLQTTRHFELLPEPTLQEAQQSLLDEITPSIAHLLSITTNHVERLARREDSLRAKCQLQEGRLSD 103
                 89************************************************************************************************* PP

                 ......HHHHT-XXXXXXXXXXXX....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  DASH_Spc19 100 aesskkeeeeseeskeeeeeeenkeeekskkkltkeelerlkkLkqkKerLkytlerL 157
                 +++  ++++  +    +++   ++         +++++++l++L qkKerLky+++rL
  EEA20698.1 104 ERQLPSATQLGKAVGGSRT---GT--------DAGAKAAQLRRLVQKKERLKYAVDRL 150
                 6555555544444444222...22........24679*******************98 PP

>> Mur_ligase_M  Mur ligase middle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   4.9e-07    0.0029      57     104 ..      53      99 ..      30     112 .. 0.84

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 4.9e-07
                   -HCHHHCTTTCCHCBESEEEE---TSTTHHHHSSHHHHHHHHHHHHHT CS
  Mur_ligase_M  57 sshglgekrlegllkpdvavitnispdHldfhgtlenyaeaKaelfer 104
                   + ++ +++ l++ + p +a +++i+++H++++  +e+ ++aK++l e+
    EEA20698.1  53 TLQEAQQSLLDE-ITPSIAHLLSITTNHVERLARREDSLRAKCQLQEG 99 
                   556677899999.9******************************9865 PP

>> COG5  Golgi transport complex subunit 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.3     0.002        12      69      95 ..       4      30 ..       1      38 [. 0.87
   2 ?    5.9   0.2    0.0023        14      53      85 ..      41      73 ..      34      92 .. 0.83
   3 ?    0.8   0.1     0.086   5.2e+02      33      51 ..     138     156 ..     124     167 .. 0.70

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.002
                XXXXXXXXXXXXXXXXXXXXXXXX-TT CS
        COG5 69 slssvlselksslesLsasyerlkskv 95
                slss++ +l++sl+ L++s++ l s v
  EEA20698.1  4 SLSSSVASLRTSLHLLESSIDILDSGV 30
                67889999************9999877 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0023
                XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        COG5 53 itsnhleLlehlskskslssvlselksslesLs 85
                 t++h eLl + + ++  +s+l+e+++s++ L 
  EEA20698.1 41 QTTRHFELLPEPTLQEAQQSLLDEITPSIAHLL 73
                5789999****999999999*********9884 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.086
                 XXXXXXXXXXXXXXXXXXX CS
        COG5  33 tplkrlnydiqeldkrlrq 51 
                  + +rl+y+++ l+ + rq
  EEA20698.1 138 QKKERLKYAVDRLELQSRQ 156
                 4567788888777766555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (168 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1013  (0.0565006); expected 358.6 (0.02)
Passed bias filter:                      477  (0.0266049); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.39u 0.27s 00:00:00.66 Elapsed: 00:00:00.40
# Mc/sec: 1275.58
//
Query:       EEA20699.1  [L=58]
Description: mitochondrial F1F0 ATP synthase subunit Atp18, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.3e-27   93.8   3.2    3.6e-27   93.7   3.2    1.0  1  ATP-synt_J   ATP synthase j chain
  ------ inclusion threshold ------
          1   10.1   4.7         10    7.0   0.3    2.3  2  Parecho_VpG  Parechovirus Genome-linked protein


Domain annotation for each model (and alignments):
>> ATP-synt_J  ATP synthase j chain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.7   3.2     4e-31   3.6e-27       1      51 []       7      57 ..       7      57 .. 0.98

  Alignments for each domain:
  == domain 1  score: 93.7 bits;  conditional E-value: 4e-31
                -----SSSSSHHHHHHHHHHHHHHHHHHHHSTTSSSSSS-TTSTTTTSS-- CS
  ATP-synt_J  1 kfptpvlkpmwPFfaaglivlygvnkaqnammnsdEfknDPRNPraakgkk 51
                k+p+pv+kpm+PFfaaglivlygvn+a+na+m+s+E+k DPRNP+a+ ++k
  EEA20699.1  7 KWPVPVAKPMFPFFAAGLIVLYGVNAAANASMASNEWKDDPRNPNAKPKGK 57
                9**********************************************9876 PP

>> Parecho_VpG  Parechovirus Genome-linked protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.6    0.0061        55       7      13 ..      10      16 ..       8      20 .. 0.80
   2 ?    7.0   0.3    0.0012        10       5      14 ..      47      56 ..      45      57 .. 0.85

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0061
  Parecho_VpG  7 LPvAKPK 13
                 +PvAKP 
   EEA20699.1 10 VPVAKPM 16
                 6*****5 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0012
  Parecho_VpG  5 PtLPvAKPKG 14
                 P  P AKPKG
   EEA20699.1 47 PRNPNAKPKG 56
                 77799****9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (58 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       277  (0.0154498); expected 358.6 (0.02)
Passed bias filter:                      218  (0.0121591); expected 358.6 (0.02)
Passed Vit filter:                         9  (0.00050198); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.29u 0.24s 00:00:00.53 Elapsed: 00:00:00.36
# Mc/sec: 485.66
//
Query:       EEA20700.1  [L=60]
Description: mitochondrial F1F0 ATP synthase subunit Atp18, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.3e-16   59.9   0.8    1.5e-16   59.7   0.8    1.2  1  ATP-synt_J  ATP synthase j chain


Domain annotation for each model (and alignments):
>> ATP-synt_J  ATP synthase j chain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.7   0.8   8.2e-21   1.5e-16       1      34 [.       7      40 ..       7      55 .. 0.93

  Alignments for each domain:
  == domain 1  score: 59.7 bits;  conditional E-value: 8.2e-21
                -----SSSSSHHHHHHHHHHHHHHHHHHHHSTTS CS
  ATP-synt_J  1 kfptpvlkpmwPFfaaglivlygvnkaqnammns 34
                k+p+pv+kpm+PFfaaglivlygvn+a+na+m+ 
  EEA20700.1  7 KWPVPVAKPMFPFFAAGLIVLYGVNAAANASMAC 40
                9*******************************85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (60 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       388  (0.0216409); expected 358.6 (0.02)
Passed bias filter:                      302  (0.0168442); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.28s 00:00:00.67 Elapsed: 00:00:00.44
# Mc/sec: 410.11
//
Query:       EEA20701.1  [L=44]
Description: mitochondrial F1F0 ATP synthase subunit Atp18, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.9e-15   56.2   0.1    2.4e-15   55.8   0.1    1.2  1  ATP-synt_J  ATP synthase j chain


Domain annotation for each model (and alignments):
>> ATP-synt_J  ATP synthase j chain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.8   0.1   1.4e-19   2.4e-15      17      51 .]       9      43 ..       7      43 .. 0.96

  Alignments for each domain:
  == domain 1  score: 55.8 bits;  conditional E-value: 1.4e-19
                HHHHHHHHHHHHHHSTTSSSSSS-TTSTTTTSS-- CS
  ATP-synt_J 17 glivlygvnkaqnammnsdEfknDPRNPraakgkk 51
                glivlygvn+a+na+m+s+E+k DPRNP+a+ ++k
  EEA20701.1  9 GLIVLYGVNAAANASMASNEWKDDPRNPNAKPKGK 43
                89*****************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (44 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       234  (0.0130515); expected 358.6 (0.02)
Passed bias filter:                      188  (0.0104858); expected 358.6 (0.02)
Passed Vit filter:                         7  (0.000390429); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.34u 0.23s 00:00:00.57 Elapsed: 00:00:00.40
# Mc/sec: 330.39
//
Query:       EEA20702.1  [L=44]
Description: mitochondrial F1F0 ATP synthase subunit Atp18, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.9e-15   56.2   0.1    2.4e-15   55.8   0.1    1.2  1  ATP-synt_J  ATP synthase j chain


Domain annotation for each model (and alignments):
>> ATP-synt_J  ATP synthase j chain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.8   0.1   1.4e-19   2.4e-15      17      51 .]       9      43 ..       7      43 .. 0.96

  Alignments for each domain:
  == domain 1  score: 55.8 bits;  conditional E-value: 1.4e-19
                HHHHHHHHHHHHHHSTTSSSSSS-TTSTTTTSS-- CS
  ATP-synt_J 17 glivlygvnkaqnammnsdEfknDPRNPraakgkk 51
                glivlygvn+a+na+m+s+E+k DPRNP+a+ ++k
  EEA20702.1  9 GLIVLYGVNAAANASMASNEWKDDPRNPNAKPKGK 43
                89*****************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (44 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       234  (0.0130515); expected 358.6 (0.02)
Passed bias filter:                      188  (0.0104858); expected 358.6 (0.02)
Passed Vit filter:                         7  (0.000390429); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.36u 0.23s 00:00:00.59 Elapsed: 00:00:00.40
# Mc/sec: 329.41
//
Query:       EEA20703.1  [L=113]
Description: 40S ribosomal protein S14, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.8e-21   75.6   2.7    2.9e-21   75.0   0.3    2.0  2  Ribosomal_S14  Ribosomal protein S14p/S29e
  ------ inclusion threshold ------
       0.26   11.6   1.0       0.36   11.1   1.0    1.2  1  Synaphin       Synaphin protein


Domain annotation for each model (and alignments):
>> Ribosomal_S14  Ribosomal protein S14p/S29e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.1     0.043   3.9e+02      24      48 ..      25      49 ..      13      54 .. 0.83
   2 !   75.0   0.3   3.2e-25   2.9e-21       1      54 []      59     112 ..      59     112 .. 0.98

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.043
                   SSSEE-GGG-EHHHHHHHTTT...T CS
  Ribosomal_S14 24 prGvirkfgLsRicfRelAlkgelp 48
                    r v+ +f+  R+ +R + ++  lp
     EEA20703.1 25 KRKVFEQFEPERQALRYAIRNTSLP 49
                   5778899999999999888877766 PP

  == domain 2  score: 75.0 bits;  conditional E-value: 3.2e-25
                    S------SS..CTTT---SSS--SSSEE-GGG-EHHHHHHHTTT...TT-EE-- CS
  Ribosomal_S14   1 klaklprnssptrirnrCrvtGrprGvirkfgLsRicfRelAlkgelpGvkKaS 54 
                    +la+++ +++ t+i+nrC+  G +rGv+r+f+L R++fR++Al+gelpGvkKaS
     EEA20703.1  59 QLAQMHAYTRSTQIKNRCVAGGIARGVFRDFRLGRYQFRQQALAGELPGVKKAS 112
                    699**************************************************9 PP

>> Synaphin  Synaphin protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   1.0   4.1e-05      0.36      51      91 ..      24      63 ..      15      75 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 4.1e-05
    Synaphin 51 eRkekfrkmeaEReklRqeiRdKYrlkkkeedeaeiqaaee 91
                  ++ f++ e ER++lR  iR+   l+++  ++a+ q+a++
  EEA20703.1 24 TKRKVFEQFEPERQALRYAIRNT-SLPQRVRAQAQLQLAQM 63
                44567****************96.89999999999998854 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (113 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       449  (0.0250432); expected 358.6 (0.02)
Passed bias filter:                      341  (0.0190195); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.37u 0.25s 00:00:00.62 Elapsed: 00:00:00.39
# Mc/sec: 860.08
//
Query:       EEA20704.1  [L=396]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (396 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       430  (0.0239835); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.24s 00:00:00.73 Elapsed: 00:00:00.41
# Mc/sec: 2895.20
//
Query:       EEA20705.1  [L=531]
Description: allantoinase Dal1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-26   93.6   0.0    1.2e-25   90.5   0.0    2.2  1  Amidohydro_1  Amidohydrolase family
      2e-13   50.7   0.1    2.1e-08   34.1   0.0    2.2  2  Amidohydro_3  Amidohydrolase family


Domain annotation for each model (and alignments):
>> Amidohydro_1  Amidohydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.5   0.0   1.4e-29   1.2e-25       1     344 []      57     509 ..      57     509 .. 0.82

  Alignments for each domain:
  == domain 1  score: 90.5 bits;  conditional E-value: 1.4e-29
                   EEEE-EEEEEEECETTECSSSGHHHHHSTTHHHHHHHHHHHHHHHHTTEEEEEEEEHSSTH......HHHHHHHHHHT.SSSEEEEEEESSEGGSGC CS
  Amidohydro_1   1 ivlPGlIDaHvHleqsllrgatledwlvppetaaealesgiktalksGtttvadmgattst......giealleaaee.lplglrilggkvsldrgs 90 
                   ++lPGl+DaHvHl+             +p++t +e++ +g+++a  +G+ttv+dm+ ++++      g+++ ++aa + ++++++++gg +++  g+
    EEA20705.1  57 VLLPGLVDAHVHLN-------------EPGRTEWEGFYTGTQAAAFGGVTTVIDMPLNAIPptttaaGFKDKIRAAQDkCWVDVGFYGG-LIP--GN 137
                   589**********8.............****************************************999999988888********99.444..88 PP

                   CCSHHHHHHHHHHHHHHHHHHCTTTCEEEEEEECGTCCSHHHHHHHHHHHHHHHTTEEEEEE.......TSSCHHHHHHHHHHTTTEEEETTTTSTC CS
  Amidohydro_1  91 aetskasreklkagaaetikgkadgvvkvalapheapafsdeelkealkeakkrdlpvaiHa.......letkgevedaeaafgetiehgthlevae 180
                   a+  k ++e  ++g+       ++ ++++++ + +a++++   ++ a+k  +++ + +++Ha        +   +v+ ++   + +   +++  ++ 
    EEA20705.1 138 ADELKPLVEMGVRGF-------KGFLIDSGVEEFPAVSAP--DIELAMKTLADQPTTLMFHAemlppitDSVGDDVQVSLPPLAPSGPLQSYSTFLA 225
                   888999999999998.......444556666566555555..666699999***********76666666666666666666666666666666666 PP

                   C.......HHTTTHCCEE......EHCTCEEEHHHHHHHHHHHHHHCEE.........................HHHHHHHHSEHH..HHHHHHHHH CS
  Amidohydro_1 181 s.......lglldeikli......lahgvhltpteaellkerlkeagva.........................hcpfsnsilrsg..realrkald 237
                   s       ++++++i+l+        h+vhl++ ea+ l + ++ +gv                           cp   s+l+++  ++ l++  +
    EEA20705.1 226 SrpvsfetYAVAEIIQLAstapklPLHIVHLSAIEAIPLLREARANGVQitaetcfhylslaaeeiaegdtrhkCCPPIRSRLNQDglWAELERYAE 322
                   6*******88888888887777768899999999999999999******99*999999777777777777776555555555555544788999999 PP

                   HTSCEEEEEECT......................................................TSSCCGGHHHH............HHHHHHHH CS
  Amidohydro_1 238 eGvkvglgtDga......................................................asgnslnllee............lrlalklq 268
                   +Gv+ ++++D+                                                       a gn ++ + +            + +   + 
    EEA20705.1 323 DGVIKTVVSDHSpctpdlkllpshimqqppsdslgssdssavatphnsssnssvsdyfeepkeqevADGNFFSAWGGissvglglpilwTEISR-RK 418
                   9*********889***********************************9999999999999999998888887777788888888755433333.22 PP

                   HHCCTT...TTHCHCHHHHHHHHHTHHHHHHTT-TTTSSSS-TTSB--EEEECC......CT........CGGGTTTCTSEEEEEEEETTEEE CS
  Amidohydro_1 269 rgllye...deegglslkealrmaTingAkalglddkvGsievGkdADlvvvdl......di........laafvglkkdgnvkkvivkGklv 344
                   +         ++   +l+++ r++++n+A ++gl++++G ++vG+dAD+ ++d        +         ++++g + +g v+ ++++G+ v
    EEA20705.1 419 KIA--ApggTKTIEEDLLDIARWCSTNTAAQVGLSSTKGDLAVGFDADICIFDDsaewvvEPstmlfrnkCSPYQGRALKGMVRETWLRGQKV 509
                   223..234888999***************************************9876665227788898899****************99865 PP

>> Amidohydro_3  Amidohydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.1   2.2e-06      0.02       9      49 ..      57      97 ..      54     113 .. 0.78
   2 !   34.1   0.0   2.4e-12   2.1e-08     405     473 .]     428     510 ..     411     510 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 2.2e-06
  Amidohydro_3  9 lvlPGFvDsHtHlaggg.vnl.rllrlpdarvtslegvltavr 49
                  ++lPG+vD+H Hl + g  ++  ++   +  + ++ gv+t+++
    EEA20705.1 57 VLLPGLVDAHVHLNEPGrTEWeGFYTGTQ--AAAFGGVTTVID 97
                  89***************788844444444..888888888876 PP

  == domain 2  score: 34.1 bits;  conditional E-value: 2.4e-12
  Amidohydro_3 405 deelsleealalyTrgpAkalgledrkGtLevGadADlvvld.adpldvdppelaear.............vrltvvdGrvvy 473
                     e +l ++++ +++++A+++gl+ +kG L+vG+dAD++++d  +   v+p+++   +             vr+t+ +G+ vy
    EEA20705.1 428 TIEEDLLDIARWCSTNTAAQVGLSSTKGDLAVGFDADICIFDdSAEWVVEPSTMLFRNkcspyqgralkgmVRETWLRGQKVY 510
                   5678999***********************************65556666666655559*********************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (531 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       398  (0.0221987); expected 358.6 (0.02)
Passed bias filter:                      361  (0.020135); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 3572.36
//
Query:       EEA20706.1  [L=288]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-40  138.0   0.0    2.8e-40  137.6   0.0    1.2  1  Vma12     Endoplasmic reticulum-based factor for assembly of 
  ------ inclusion threshold ------
      0.096   12.5   0.1      0.096   12.5   0.1    2.0  2  LapA_dom  Lipopolysaccharide assembly protein A domain


Domain annotation for each model (and alignments):
>> Vma12  Endoplasmic reticulum-based factor for assembly of V-ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.6   0.0   3.1e-44   2.8e-40       2     139 .]      62     224 ..      61     224 .. 0.87

  Alignments for each domain:
  == domain 1  score: 137.6 bits;  conditional E-value: 3.1e-44
       Vma12   2 LlrgskvyvpppppkpepspEykallarLraeqeereYkrlinsvdpsqksgktdspss...............sd.deltaqelkevnrqlilvlNil 84 
                 Llrg+kvy+pppppkpepspEy+al+arL+a ++e++Y++li +++++ +  k    s+               +d d++t          ++lv+Ni+
  EEA20706.1  62 LLRGTKVYIPPPPPKPEPSPEYLALKARLQALADEQAYNALIAPSSTHLNPYKP---SPifsdnsmmptaienvEDsDSIT----------PSLVINIF 147
                 9*******************************************7755443333...334433344444444332245555..........******** PP

       Vma12  85 iSvvavffavwialrsartp......................slpvrvllslvvallVgvAEvvvyakylrkveeak 139
                 +Sv+ ++fa+++al+++ tp                      ++pv vl+s++v++lVgvAE+vvya+ylrkv+ ak
  EEA20706.1 148 MSVILCGFATFWALKNFQTPsflswvllspsgdpakrragasKDPVFVLISMFVGILVGVAETVVYAAYLRKVKYAK 224
                 *****************999******************************************************997 PP

>> LapA_dom  Lipopolysaccharide assembly protein A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.6      0.57   5.1e+03      27      40 ..     146     159 ..     142     164 .. 0.65
   2 ?   12.5   0.1   1.1e-05     0.096      22      60 ..     194     234 ..     192     237 .. 0.88

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.57
    LapA_dom  27 fgiGallgwllslw 40 
                 +++ ++l +++++w
  EEA20706.1 146 IFMSVILCGFATFW 159
                 56667777777777 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 1.1e-05
    LapA_dom  22 lllvafgiGallgwllsl..wsylrlrrelrrlkkkikkle 60 
                  +l+++++G+l+g+  ++   +ylr+ + +++++kk+k+ +
  EEA20706.1 194 FVLISMFVGILVGVAETVvyAAYLRKVKYAKAAEKKVKERK 234
                 689***********98885569****************965 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (288 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       670  (0.0373696); expected 358.6 (0.02)
Passed bias filter:                      521  (0.0290591); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 1928.05
//
Query:       EEA20707.1  [L=206]
Description: prefoldin subunit 3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.3e-28   98.0   1.7    3.3e-28   98.0   1.7    1.7  2  Prefoldin     Prefoldin subunit
     0.0039   17.1   0.6      0.016   15.1   0.0    2.1  2  Prefoldin_2   Prefoldin subunit
  ------ inclusion threshold ------
      0.015   15.8   0.7          1   10.0   0.1    2.3  2  Syntaxin-6_N  Syntaxin 6, N-terminal
      0.016   15.0   4.0       0.61    9.8   0.1    2.2  2  DUF4201       Domain of unknown function (DUF4201)


Domain annotation for each model (and alignments):
>> Prefoldin  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0       1.6   7.1e+03      87     100 ..      33      46 ..      26      48 .. 0.57
   2 !   98.0   1.7   7.5e-32   3.3e-28       1     120 []      49     185 ..      49     185 .. 0.98

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 1.6
                 HHHHHHHHHHHHHH CS
   Prefoldin  87 eelekqlekleeel 100
                 +e+e++l++++e++
  EEA20707.1  33 AEVESTLRSFQEMI 46 
                 34555555555555 PP

  == domain 2  score: 98.0 bits;  conditional E-value: 7.5e-32
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT................-TT-EEEEEEETTEEEEEE-..-STTEEEEEEETTEEEEEEHHHHHHHH CS
   Prefoldin   1 lkeeleslqaelaqlkeaieelektletlktlkk...............edegkevlvplgaglyvkaev..kdtdkvlvdlGagyyveksleeAiell 82 
                 +++++ + q++ a lke+i++++ktl++++ lk                ++ g e++++l+++ly++a+v  kdtd+v+++lGa++++ +++ eA++ l
  EEA20707.1  49 YQFMEMNTQRRSAGLKEKIPDIKKTLDMVRFLKLnrenneddeddeeeeGKGGLETHFELNDTLYARAKVaaKDTDEVYLWLGANVMLAYPIAEAETML 147
                 899******************************************999888899*****************9*************************** PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Prefoldin  83 kkkleelekqlekleeeleklkdqittleanlaqlyqk 120
                  +kl+ +e +l ++ee+le+l++qittle++ a++y++
  EEA20707.1 148 TEKLSAAELSLANCEEDLEFLREQITTLEVATARVYNW 185
                 ************************************98 PP

>> Prefoldin_2  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1      0.51   2.3e+03      79      79 ..      61      61 ..      39      78 .. 0.43
   2 !   15.1   0.0   3.7e-06     0.016      43      97 ..     122     177 ..     104     182 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.51
                 H CS
  Prefoldin_2 79 k 79
                 +
   EEA20707.1 61 A 61
                 2 PP

  == domain 2  score: 15.1 bits;  conditional E-value: 3.7e-06
                  TT--EEEEET.TEEEEE-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Prefoldin_2  43 edtkvyklvG.dvlvkqdkeevkeeLeerketlekeiktlekqleklekeleelke 97 
                  ++++vy   G +v++  + +e++++L e++  +e  ++++e+ le l+++++ l+ 
   EEA20707.1 122 DTDEVYLWLGaNVMLAYPIAEAETMLTEKLSAAELSLANCEEDLEFLREQITTLEV 177
                  55778888875689999**********************************99975 PP

>> Syntaxin-6_N  Syntaxin 6, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.1   0.00022         1       3      51 ..      28      75 ..      27      80 .. 0.82
   2 ?    4.4   0.1     0.012        56      47      77 ..     155     186 ..     103     194 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00022
  Syntaxin-6_N  3 FfevkeeVqkslnkaeslyrrwerlledtssstseeldetrteLrkalr 51
                  +++ ++eV+++l++ ++++++++ +   +++++s  l+e   +++k+l+
    EEA20707.1 28 YVSSRAEVESTLRSFQEMISKYQFME-MNTQRRSAGLKEKIPDIKKTLD 75
                  77889*****************8544.4444569999999999999886 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.012
  Syntaxin-6_N  47 rkalrsiewdledLeetvriveknpsk.fkid 77 
                   + +l + e+dle L+e + ++e   ++ ++ d
    EEA20707.1 155 ELSLANCEEDLEFLREQITTLEVATARvYNWD 186
                   45688999**********99998766655544 PP

>> DUF4201  Domain of unknown function (DUF4201)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   0.9    0.0018         8      77     125 ..      40      88 ..      27      99 .. 0.55
   2 ?    9.8   0.1   0.00014      0.61      84     122 ..     142     180 ..     133     193 .. 0.90

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0018
     DUF4201  77 halthlkeklhmleselselkkelkekeerlaklrkelykvklerdklr 125
                    +++  k +++e++ +++   lkek  +++k  + +  +kl+r++ +
  EEA20707.1  40 RSFQEMISKYQFMEMNTQRRSAGLKEKIPDIKKTLDMVRFLKLNRENNE 88 
                 4444444555555555555555555555555555555555555555544 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00014
     DUF4201  84 eklhmleselselkkelkekeerlaklrkelykvklerd 122
                 e ++ml+++ls+++ +l ++ee+l+ lr++++ ++   +
  EEA20707.1 142 EAETMLTEKLSAAELSLANCEEDLEFLREQITTLEVATA 180
                 7889***************************99987655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (206 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1127  (0.0628591); expected 358.6 (0.02)
Passed bias filter:                      644  (0.0359195); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.50u 0.29s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 1382.38
//
Query:       EEA20708.1  [L=244]
Description: eukaryotic translation initiation factor 3 subunit EifCk, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.9e-48  164.1   0.0    2.4e-48  163.8   0.0    1.1  1  CSN8_PSD8_EIF3K  CSN8/PSMD8/EIF3K family


Domain annotation for each model (and alignments):
>> CSN8_PSD8_EIF3K  CSN8/PSMD8/EIF3K family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  163.8   0.0   1.3e-52   2.4e-48       2     143 ..      65     221 ..      64     222 .. 0.98

  Alignments for each domain:
  == domain 1  score: 163.8 bits;  conditional E-value: 1.3e-52
  CSN8_PSD8_EIF3K   2 lkaelytniLlkaLtqndladfrlllkrlpaaiqqs.............deeiqklltLetlLeeanyakfwstlksddlsadltadvagleel 82 
                      l++e++tniL+kaLt++++++f+l+l++lpa++q++              e+iqkl++L+tlLe+a+ya fwst +sddl+adl+advag+eel
       EEA20708.1  65 LQTETTTNILAKALTVFPSPAFSLSLALLPAHTQPFgastddgaqssdfVESIQKLAHLNTLLESAQYALFWSTFNSDDLYADLVADVAGFEEL 158
                      789******************************************************************************************* PP

  CSN8_PSD8_EIF3K  83 vReeiaklvgkaYesIsadvlaelLglssdeelekfvkev.gWeldaatvivpfnpe.eakpe 143
                      vR +ia +vgk++++Isad la++ +l+s e+l+kfv++v gWe+++a v+vp+n e ea++e
       EEA20708.1 159 VRVRIAVEVGKTFREISADTLAQWFDLKSREALQKFVVDVcGWEVEGALVRVPKNREnEARSE 221
                      *********************************************************998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (244 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       447  (0.0249317); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.46
# Mc/sec: 1592.09
//
Query:       EEA20709.1  [L=497]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    7.4e-54  182.5   0.9      2e-53  181.1   0.0    2.1  3  Folliculin  Vesicle coat protein involved in Golgi to plasma 


Domain annotation for each model (and alignments):
>> Folliculin  Vesicle coat protein involved in Golgi to plasma membrane transport
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.2      0.12   2.1e+03     140     140 ..      86      86 ..      47     179 .. 0.58
   2 !  181.1   0.0   1.1e-57     2e-53       2     184 ..     232     415 ..     231     416 .. 0.95
   3 ?   -3.3   0.4       0.4   7.1e+03     134     153 ..     443     462 ..     432     477 .. 0.38

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.12
  Folliculin 140 s 140
                 s
  EEA20709.1  86 S 86 
                 1 PP

  == domain 2  score: 181.1 bits;  conditional E-value: 1.1e-57
  Folliculin   2 sYvStqePlsperysllrqaclrsLScEtlpr.asggpifFgDeaaGytlayiFrlkDvkARGkkRvYalialstdkerlllkawsfiveafeklaaei 99 
                 +Y+S + P +p+ y+llrq+ +r+LScE+lpr  s+gp++FgD++aGyt+ay+Frl+D++ARGk+R+Yalial+++++ ++++a ++i++ f+++aa i
  EEA20709.1 232 TYLSLHGPPNPNDYALLRQSSIRTLSCELLPRgLSSGPLCFGDPVAGYTIAYVFRLPDPMARGKRRSYALIALAGKDAGRAFRASPIIWRIFQRIAAGI 330
                 7*******************************99***************************************************************** PP

  Folliculin 100 qalaeaelereskeeeassaassssalkadgsglsrregssfslskekylrrsksklkarsLaelvgdediFvelHawfvwlLke 184
                  ++ae+++e+e+ +ee++ ++s++sa +  ++ l+ ++  + ++  ++ + r+  +++ar+Lae+vg+e iF+elHa+fv+lL++
  EEA20709.1 331 VTAAEKHQEEEKMREEQAFRSSNTSAATGRQNYLPISSFLTGRTLDANGNPRRAGQIRARNLAEIVGNEYIFAELHAQFVTLLQQ 415
                 *************99999888888888888888888877777888888889999999**************************98 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 0.4
  Folliculin 134 srregssfslskekylrrsk 153
                 s++ ++s+++ +++ +++++
  EEA20709.1 443 SQSRRTSVAMPNNNNNNNNQ 462
                 22222222222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (497 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       940  (0.052429); expected 358.6 (0.02)
Passed bias filter:                      435  (0.0242624); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.33s 00:00:00.92 Elapsed: 00:00:00.50
# Mc/sec: 3004.36
//
Query:       EEA20710.1  [L=354]
Description: hypothetical protein PMAA_045320 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
     0.0023   17.0   0.0     0.0038   16.3   0.0    1.3  1  Fungal_trans  Fungal specific transcription factor domain
  ------ inclusion threshold ------
      0.056   13.6   9.8       0.11   12.6   9.8    1.5  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   4.2e-07    0.0038     128     206 ..     226     307 ..     204     331 .. 0.89

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 4.2e-07
  Fungal_trans 128 gLhrnpsyvgkks.....lwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddlwesddaseetlvet 206
                   +Lhr+ s  ++ +     +w+ w+  ae+ rR+ +  + +  +++ + G p++l  +   lp P     lw + ++ e++++++
    EEA20710.1 226 MLHREMSAIYDQRreyddIWEAWVV-AEAKRRTLYVMYLFNSLLSAQDGLPTFLGTELYGLPAPSAGA-LWKAGTRQEWERQYN 307
                   567777766665588888*******.******************************************.***********9985 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   9.8   1.3e-05      0.11       1      24 [.      12      35 ..      12      37 .. 0.94

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.3e-05
                SS-HHHHHCT---STSSSS-HHHH CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCk 24
                +aC++C + K KCd + + Cs+C 
  EEA20710.1 12 KACQHCLSAKAKCDLRDGGCSRCL 35
                59*************9999****5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (354 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       384  (0.0214178); expected 358.6 (0.02)
Passed bias filter:                      265  (0.0147805); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2475.95
//
Query:       EEA20711.1  [L=324]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.4e-39  135.1  51.0    8.3e-39  133.8  39.3    3.0  2  RNA_polI_A34  DNA-directed RNA polymerase I subunit RPA34.5
  ------ inclusion threshold ------
       0.99    8.9  25.9       0.29   10.7  15.3    2.1  2  PPP4R2        PPP4R2
        8.3    6.6  29.8        9.2    6.5  21.4    2.4  2  PNISR         Arginine/serine-rich protein PNISR


Domain annotation for each model (and alignments):
>> RNA_polI_A34  DNA-directed RNA polymerase I subunit RPA34.5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   3.8      0.05     3e+02     128     166 ..       9      53 ..       2      82 .. 0.49
   2 !  133.8  39.3   1.4e-42   8.3e-39       1     188 [.      97     303 ..      97     324 .] 0.80

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.05
                   X............XXXXXXXXXXXXXXXXXXXXXXXX.......X CS
  RNA_polI_A34 128 tigssseesegekekkkkpkakkkekkkkkkkaaeede......e 166
                   ++ s+s+es+++ ++ +  ++kk++k    ++a e+++      e
    EEA20711.1   9 VVVSDSDESMEDAPETTSVNTKKNAKVSPNQGATESSSefdssdE 53 
                   455566665555555444444444444444444444322222111 PP

  == domain 2  score: 133.8 bits;  conditional E-value: 1.4e-42
                   STTEEEEEEEEETTS-GGG-S..EE---SSCSEEEE.EETTEEEEEEEGGGCS-GTTEEEEEE-SSSTB-TTSS.-B-SEEEEEEE--XXXXXX... CS
  RNA_polI_A34   1 legkelWlIkaPasvpikslegvevplsgvqtgksvlshkgqdYgiledsdeeekggerlLlpdkkkdgyelaa.kpisrtlnisevvqlpstd... 93 
                   legk++++I+aP+ +p+++++  ++   ++++g++++shkg+dYg+ e+++++++++e lL++d+k+++y   +  +  +++ni+e+v+lp+ d   
    EEA20711.1  97 LEGKQVFHITAPSYLPLSEMK--QITFGKATSGEPIISHKGVDYGLVETTRQQKQSSETLLIYDEKSNTYLRKPeLRKIESYNIQEIVRLPGLDtlv 191
                   58*******************..****************************999*******************99*******************886 PP

                   ...XXXX....XXXXXXXXXXXXXXXXXXXXXXXXXXXXX............XXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXX CS
  RNA_polI_A34  94 ...aepaas..vvpkpprpqpkgLkmRFkPfGsgdgppgtigssseesegekekkkkpkakkkekkkkkkkaaeedeeeeapkkkkkkkkkkkekke 185
                      +    +  +++ + rpqpk+L+mRF+P+Gs++ pp+t+gssse+ e +++++++p++++kek++k +k++++++   +++k kk+kk+k++  +
    EEA20711.1 192 ppsQ----NatKKQPAARPQPKHLRMRFHPVGSTTLPPETVGSSSES-EADEPTSRVPATSSKEKAEKDRKRKTDEQ-NGTEEKAKKSKKDKQQSSQ 282
                   5432....233777779***************************999.99********************9999995.3333343333333333333 PP

                   ....................X CS
  RNA_polI_A34 186 ee..................k 188
                   +e                  +
    EEA20711.1 283 AElqtegrrdkekksskhrdE 303
                   334457777777766664430 PP

>> PPP4R2  PPP4R2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   2.9    0.0043        25     190     238 ..      12      61 ..       5      97 .. 0.69
   2 ?   10.7  15.3   4.9e-05      0.29     183     284 ..     217     319 ..     139     324 .] 0.49

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.0043
      PPP4R2 190 vdekteselspfikeidsimsvnlgfedeeekeedd.neseesaseseei 238
                 +d++++ e++p+ + +++  +++ + ++   +++++ ++s+es+se++++
  EEA20711.1  12 SDSDESMEDAPETTSVNTKKNAKVSPNQGATESSSEfDSSDESSSETQNN 61 
                 56777778888888888888888888777777775543333333333322 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 4.9e-05
      PPP4R2 183 slvsipwvdekteselspfikeidsimsvnlgfedeeekeedd....neseesaseseeiteekdesvkveekdddeeddeedtdyveeeeddeseddd 277
                 +  s    +e+ +s+++++  e++s + +++++e++e++ + +    n    +++++++  + k++s++ e +++  +d+e+++  + +e+++e    +
  EEA20711.1 217 PVGSTTLPPETVGSSSESEADEPTSRVPATSSKEKAEKDRKRKtdeqN---GTEEKAKKSKKDKQQSSQAELQTEGRRDKEKKSSKHRDETSQERRARK 312
                 333444444555566666666666665555555555555543321111...111111111112222222222333444444444444444444444444 PP

      PPP4R2 278 eeeeeee 284
                 ee+++ +
  EEA20711.1 313 EEKKKRK 319
                 3333333 PP

>> PNISR  Arginine/serine-rich protein PNISR
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   1.2    0.0039        23      48      80 ..      29      61 ..       5     102 .. 0.58
   2 ?    6.5  21.4    0.0015       9.2      19     138 ..     250     316 ..     199     324 .] 0.53

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.0039
       PNISR 48 esskeeeeaknprnlakskfdsedeksdeeeee 80
                 ++  + ++++ ++ ++s+fds+de+s+e +++
  EEA20711.1 29 TKKNAKVSPNQGATESSSEFDSSDESSSETQNN 61
                122233344444555566666666555555432 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0015
       PNISR  19 EKmerEKqkklererrekeraerrkeekkesskeeeeaknprnlakskfdsedeksdeeeeegaegedsesqekasskksevdeqespeeeeaarkeie 117
                 EK+e+++++k + +  ++e+a+++k++k++ss+ e + +++r  +k  +++ de s+e                                         
  EEA20711.1 250 EKAEKDRKRKTDEQNGTEEKAKKSKKDKQQSSQAELQTEGRRDKEKKSSKHRDETSQERR--------------------------------------- 309
                 455555555555555555555554444444443333333333333333333333222222....................................... PP

       PNISR 118 esspaeeeeeeepeakteeek 138
                               a +ee+k
  EEA20711.1 310 --------------ARKEEKK 316
                 ..............1111111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (324 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2677  (0.149311); expected 358.6 (0.02)
Passed bias filter:                      661  (0.0368676); expected 358.6 (0.02)
Passed Vit filter:                       222  (0.0123822); expected 17.9 (0.001)
Passed Fwd filter:                        64  (0.00356964); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 1.00u 0.36s 00:00:01.36 Elapsed: 00:00:00.54
# Mc/sec: 1816.03
//
Query:       EEA20712.1  [L=813]
Description: RNA processing protein Grc3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.7e-26   90.7   0.0    1.9e-25   89.7   0.0    1.5  1  CLP1_P        mRNA cleavage and polyadenylation factor CLP1 P
     0.0061   16.8   0.6       0.19   12.0   0.0    2.7  2  AAA_22        AAA domain
  ------ inclusion threshold ------
      0.033   14.8   0.2       0.22   12.1   0.0    2.4  2  AAA_18        AAA domain
      0.041   13.6   0.0      0.091   12.5   0.0    1.5  1  AAA_29        P-loop containing region of AAA domain
      0.058   13.8   0.0       0.34   11.3   0.0    2.1  2  RNA_helicase  RNA helicase
      0.076   13.2   2.2       0.41   10.8   0.1    2.9  3  AAA_33        AAA domain
       0.18   11.5   0.0       0.34   10.6   0.0    1.4  1  AAA_24        AAA domain
       0.24   11.7   5.0        3.9    7.8   0.0    3.6  4  AAA_16        AAA ATPase domain
       0.25   11.8   3.3       0.96    9.9   0.0    2.6  3  AAA_23        AAA domain


Domain annotation for each model (and alignments):
>> CLP1_P  mRNA cleavage and polyadenylation factor CLP1 P-loop
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.7   0.0   9.7e-29   1.9e-25       1     187 [.     312     512 ..     312     513 .. 0.83

  Alignments for each domain:
  == domain 1  score: 89.7 bits;  conditional E-value: 9.7e-29
      CLP1_P   1 GpkdsGKSTlarlLlNyal.......rkgr.kpvyvDlDvGqseispPgtislalverpi........dveegfsldaplvyffGdtspsdnpslylal 83 
                 Gpk +GKST+ r+LlN +l       + +   ++++DlD+Gq+e++p g i la +++p         + +++   +    +++G tsp+++p++y  +
  EEA20712.1 312 GPKGAGKSTFGRYLLNHLLtpapdgtSDNLdGIAFLDLDPGQPEFAPMGNIYLAHLREPCfgppfshpNLDNSRYGKIIRCHHIGATSPKEDPDNYALA 410
                 9*****************9666555434432566**************************888887543333333455568****************** PP

      CLP1_P  84 vkelareveekleenkkakasgliIntpGwvkglgaellleliealepdvvvvldq...eellnelkrdlplskvkvvklpkspgvvqrsreerrelre 179
                 +  l+++++  l +   + + +liIn pGw+ glg+e+ + +i+    + vv++++    e  + l +++   +v +++lp++p   ++   + ++lr+
  EEA20712.1 411 IMNLLDQYRM-LTA--TYPRCPLIINFPGWIFGLGLEVATWIIRSTGLSDVVYMSEkgpTEVIEPLGQAASEAGVALTTLPSQPV--DTVTRSSAQLRS 504
                 *********3.333..5899****************************9999998856666677777777788888888888765..57788889**** PP

      CLP1_P 180 erireYFy 187
                 ++i++YF+
  EEA20712.1 505 MQIQSYFH 512
                 *******9 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.0   9.7e-05      0.19       8      29 ..     308     329 ..     303     345 .. 0.91
   2 ?    1.9   0.2      0.13   2.6e+02      56     104 ..     738     787 ..     721     802 .. 0.66

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 9.7e-05
      AAA_22   8 lvvtGesGtGKTtllrrlleql 29 
                 ++++G++G+GK+t  r ll+ l
  EEA20712.1 308 TLICGPKGAGKSTFGRYLLNHL 329
                 68****************9987 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.13
      AAA_22  56 llrellralglelkaerlsseellealeqalrarav.ielliiDEaqhlr 104
                 l+r+ ++a g e ++ r ++ e l++l++ +ra+++ + l +iD+a  l 
  EEA20712.1 738 LRRNKAEAHGKEDDETRREQTEQLRRLQERVRAASKlPYLKVIDDASALH 787
                 44444444444444434444444577888888888889999*****9984 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   0.00011      0.22       2      22 ..     309     329 ..     309     349 .. 0.82
   2 ?   -1.7   0.1         2     4e+03      47      67 ..     751     771 ..     706     806 .. 0.60

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00011
      AAA_18   2 lltGtpGvGKttlakeLskrl 22 
                 l++G+ G+GK+t++++L ++l
  EEA20712.1 309 LICGPKGAGKSTFGRYLLNHL 329
                 69***************7775 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 2
      AAA_18  47 deskrldedkldklldaleen 67 
                 de++r+++++l +l++ ++++
  EEA20712.1 751 DETRREQTEQLRRLQERVRAA 771
                 333344444433333333333 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   4.6e-05     0.091      20      38 ..     302     321 ..     291     334 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 4.6e-05
      AAA_29  20 dlkg.atlltGpsGsGKSTl 38 
                 + ++  tl+ Gp G+GKST+
  EEA20712.1 302 RAHSlRTLICGPKGAGKSTF 321
                 444557*************6 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00017      0.34       2      26 ..     309     333 ..     308     343 .. 0.84
   2 ?   -1.0   0.0       1.1   2.2e+03      25      61 ..     712     749 ..     699     771 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00017
  RNA_helicase   2 wlyGpsgeGKStlakeLakallkkl 26 
                   +++Gp+g GKSt+ ++L ++ll+  
    EEA20712.1 309 LICGPKGAGKSTFGRYLLNHLLTPA 333
                   69***************99999655 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 1.1
  RNA_helicase  25 klklkkkdsvys.rnpeddfwdgYtgqevvvidDfgqv 61 
                   + +   ++++y+ rn+e+df  + ++   +  +  g+ 
    EEA20712.1 712 SPDWAFSEEYYAaRNAEQDFTTQISQLRRNKAEAHGKE 749
                   5556667889999*******999887666655555555 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.1    0.0002      0.41       3      22 ..     309     328 ..     308     332 .. 0.88
   2 ?   -0.2   0.0       0.5     1e+03      50     120 ..     625     727 ..     601     748 .. 0.56
   3 ?   -1.5   0.4       1.3   2.6e+03      52      86 ..     757     792 ..     734     800 .. 0.53

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.0002
      AAA_33   3 llvGlpGsGKstlaerllkk 22 
                 l++G++G+GKst+ + ll++
  EEA20712.1 309 LICGPKGAGKSTFGRYLLNH 328
                 78***********9998865 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.5
      AAA_33  50 rvldrlyqilnelarkalsagrnvil....datnlsr.rerarflklarrlgvp...........................vrivvvetdeetlkeRla 116
                 + ++r+++ ln++++++  +g ++++     +t l++   r+  l+++r ++v                            vr +v ++d++  +e  a
  EEA20712.1 625 QSRQRVKDLLNDTITRCPNSGLPYLFwgagSSTPLDPkGSRSLGLAFVRSIDVSsqrlelispipsssirdainqgqslvlVRGMVDSPDWAFSEEYYA 723
                 455677888888888888888887776555555555444555555555555554444444444444444444444444444444444555555555555 PP

      AAA_33 117 kRaa 120
                 +R+a
  EEA20712.1 724 ARNA 727
                 5555 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 1.3
      AAA_33  52 ldrlyqilnelarkalsagrn.vildatnlsrrera 86 
                  ++  ++l+e++r a +  +  vi da  l ++er+
  EEA20712.1 757 QTEQLRRLQERVRAASKLPYLkVIDDASALHQNERR 792
                 222334555666666666655355566666666665 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00017      0.34       3      45 ..     306     348 ..     304     361 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00017
      AAA_24   3 lkiliyGpsgiGKTtlakelgpkplfidtekGlksldadkfpd 45 
                 l+ li Gp g+GK+t+ + l ++ l    ++ +++ld++ f d
  EEA20712.1 306 LRTLICGPKGAGKSTFGRYLLNHLLTPAPDGTSDNLDGIAFLD 348
                 7899****************77777777777888888887765 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.7     0.089   1.8e+02      57     119 ..       5      81 ..       2     109 .. 0.59
   2 ?    7.8   0.0     0.002       3.9      25      51 ..     306     332 ..     294     363 .. 0.79
   3 ?   -2.1   0.0       2.2   4.4e+03     106     134 ..     612     645 ..     582     651 .. 0.59
   4 ?    0.0   0.2      0.48   9.7e+02       5      23 ..     754     772 ..     725     783 .. 0.88

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.089
      AAA_16  57 rgkcdqlesaipysalaqalareellrqlldeaesaeleawrekleeala..............avpelagaeasrl 119
                 + k+++ +s++p+sa+  ++ar+   +ql +  +s e ++ + + ++  a              +++++++a ++rl
  EEA20712.1   5 KRKAEKQQSSAPRSAVSAVAARRARQQQLQEVVSSHENAPNQNQETGPPAkkvrpsldrtakdvPTSNIERANRNRL 81 
                 5678888999***9977777674554444444444444444444444333444444444444443333333333444 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.002
      AAA_16  25 elvllsGesGvGKsslvrellralekd 51 
                   +l+ G++G GKs+  r ll++l + 
  EEA20712.1 306 LRTLICGPKGAGKSTFGRYLLNHLLTP 332
                 457999************999999877 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 2.2
      AAA_16 106 a....avpelagaea.srllellkrllallsrde 134
                       +++l+++++ +r+ +ll++ + ++++ +
  EEA20712.1 612 DhetpNAGQLSASQSrQRVKDLLNDTITRCPNSG 645
                 1222223444444446888888888888777755 PP

  == domain 4  score: 0.0 bits;  conditional E-value: 0.48
      AAA_16   5 ReeeleqLlsalervrsgr 23 
                 R+e++eqL+++ ervr+ +
  EEA20712.1 754 RREQTEQLRRLQERVRAAS 772
                 8999999999999998866 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.1       3.1   6.2e+03     153     179 ..      86     123 ..      10     137 .. 0.59
   2 ?    9.9   0.0   0.00048      0.96      22      35 ..     308     321 ..     304     329 .. 0.95
   3 ?    1.6   0.2      0.17   3.4e+02     162     191 ..     725     767 ..     665     794 .. 0.54

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 3.1
      AAA_23 153 e...........rleelekeleeledekkllekleqek 179
                 +            ++++e  + e++ +++ + ++++e+
  EEA20712.1  86 KatsadlafelsNIDAAEALKSEASGVEEIISDQNDEE 123
                 13333333333344445555555555555555544433 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.00048
      AAA_23  22 tlItGpNGaGKTTi 35 
                 tlI+Gp GaGK+T+
  EEA20712.1 308 TLICGPKGAGKSTF 321
                 8************6 PP

  == domain 3  score: 1.6 bits;  conditional E-value: 0.17
      AAA_23 162 leeledekkllekl.............eqekekekeleeleee 191
                  + ++d+  ++ +l             e + e+ ++l  l+e+
  EEA20712.1 725 RNAEQDFTTQISQLrrnkaeahgkeddETRREQTEQLRRLQER 767
                 2222222222222222222222322224444444455555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (813 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1216  (0.0678231); expected 358.6 (0.02)
Passed bias filter:                      667  (0.0372023); expected 358.6 (0.02)
Passed Vit filter:                        82  (0.0045736); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.84u 0.32s 00:00:01.15 Elapsed: 00:00:00.51
# Mc/sec: 4766.53
//
Query:       EEA20713.1  [L=391]
Description: PDCD2_C domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    8.1e-41  140.0   0.0    1.2e-40  139.4   0.0    1.3  1  PDCD2_C    Programmed cell death protein 2, C-terminal putati
  ------ inclusion threshold ------
      0.073   13.3   0.2       0.14   12.3   0.2    1.5  1  zf-RING_7  C4-type zinc ribbon domain


Domain annotation for each model (and alignments):
>> PDCD2_C  Programmed cell death protein 2, C-terminal putative domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.4   0.0   1.3e-44   1.2e-40       1     175 []     205     387 ..     205     387 .. 0.85

  Alignments for each domain:
  == domain 1  score: 139.4 bits;  conditional E-value: 1.3e-44
     PDCD2_C   1 fpelelvveee.peekekeeeseedkeekekseleellseeeeeekskeekeseeeelekyeksldktfekFkkriaaepeQvlRYelggkPLwls... 95 
                 ++e++l++++e  +  ++++ + ++++++e+ e+               ++  + ++++++e+s+dk f +F++r++++peQ lRYe+gg+PL++s   
  EEA20713.1 205 YKEYYLDADYEtLS--RPSTPTIPANTTVENVEE---------------DAGGAVDTKDAFESSMDKDFLRFSTRLEHNPEQALRYEFGGTPLLYSgrd 286
                 78999999998333..444445554443322222...............22224678999**999********************************** PP

     PDCD2_C  96 .................skkspeeesdipkCsnCgskrvFEfQlmPqlinvLeveee......ekesldWgtilVytCeksCeekeeeeneegyveEfv 171
                                   ++s +++++ip+C++Cg++rvFE+Ql+P+ i+vLe  ++      ++++++Wgti+  +C+ +C   +++e++ g++eE++
  EEA20713.1 287 avakafpshqaqgrgvqVSSSASTNNRIPRCPSCGRERVFELQLVPHTITVLEDGRDgiglgkDDAGMEWGTIILGVCAGNCG--TTKEGDLGWKEEWI 383
                 *****************5566677779**************************9999*****999*****************6..66689********* PP

     PDCD2_C 172 lvQw 175
                 +vQw
  EEA20713.1 384 GVQW 387
                 ***9 PP

>> zf-RING_7  C4-type zinc ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.2   1.6e-05      0.14      20      31 ..     311     322 ..     302     322 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.6e-05
                 STB-EE-TTT-- CS
   zf-RING_7  20 gdevvtCpeCGR 31 
                 ++ +++Cp+CGR
  EEA20713.1 311 NNRIPRCPSCGR 322
                 378********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (391 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       446  (0.0248759); expected 358.6 (0.02)
Passed bias filter:                      355  (0.0198003); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 2697.79
//
Query:       EEA20714.1  [L=542]
Description: prenylcysteine lyase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   4.7e-101  338.5   0.1     6e-101  338.2   0.1    1.0  1  Prenylcys_lyase  Prenylcysteine lyase
    1.3e-12   47.8   0.0    2.8e-12   46.7   0.0    1.6  1  NAD_binding_8    NAD(P)-binding Rossmann-like domain
    1.9e-11   43.9   0.0    5.4e-11   42.5   0.0    1.6  1  Amino_oxidase    Flavin containing amine oxidoreductase
    3.6e-06   26.8   0.3    6.9e-06   25.9   0.3    1.4  1  DAO              FAD dependent oxidoreductase
     0.0011   18.2   0.1     0.0035   16.6   0.0    1.7  2  Thi4             Thi4 family
     0.0055   16.7   0.0      0.061   13.3   0.0    2.1  2  NAD_binding_9    FAD-NAD(P)-binding
  ------ inclusion threshold ------
      0.014   14.6   0.0      0.044   13.0   0.0    1.7  2  Pyr_redox_2      Pyridine nucleotide-disulphide oxidoreductas
       0.13   12.8   0.1        6.2    7.5   0.0    2.4  2  Pyr_redox        Pyridine nucleotide-disulphide oxidoreductas


Domain annotation for each model (and alignments):
>> Prenylcys_lyase  Prenylcysteine lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  338.2   0.1  2.7e-104    6e-101       4     358 ..     151     523 ..     148     525 .. 0.94

  Alignments for each domain:
  == domain 1  score: 338.2 bits;  conditional E-value: 2.7e-104
  Prenylcys_lyase   4 sswsllnllkLlwrYGlsllrlqmwveeildkFlriYelqekgyaFssveellealggkefleltkvtleealekagisekfinelvqavlrvn 97 
                      +s s++++ kLlwrYGl+++r+q++++++++kFl++Y+   + ++Fss+++ +ealg   + ++t  t+ ++l+++gise f+ne++q+++rvn
       EEA20714.1 151 HSLSWWDMTKLLWRYGLAPIRTQSLMKSTVNKFLEMYK--PPYFPFSSLSSTVEALG---LHKATALTGVQFLKTNGISESFSNEIIQSSTRVN 239
                      6789**********************************..****************9...********************************** PP

  Prenylcys_lyase  98 Yg.qsvkinalvgavslAgaqsglwavegGnkqvcsgllkkskanv.inatVtsielksgessslYevtykkes.gtesklyDiVviAtPlqkk 188
                      Yg +   i++l+++v++A  ++g++a+e+Gn++++sg+l++s+a+v +n+tVt+i+++++es     ++y+++  + +s+++D+VviA+P+q+ 
       EEA20714.1 240 YGqNLGLIHGLEAMVCMA--TDGAVAIEDGNWRIFSGMLDSSRAEVtLNSTVTAIKQNNDES---LILSYSSNGdSISSRVFDEVVIAAPFQY- 327
                      **8899************..*************************************88886...566666655488999************8. PP

  Prenylcys_lyase 189 esnisfenfsppieefkeeyqklvatlvag..rlnssyFglkeksefplstilttenpelei.........nslssvssvetskskeekkakee 271
                       sni+++   +++++ k +y+kl++tl+a+  ++++++F+l e++++p ++iltt +  +++         +s++s+s +++ ++++e+++k++
       EEA20714.1 328 -SNIEVSPSLERVPD-KIPYVKLFVTLFASphQISPEFFNLLEQKDVP-EMILTTLPRGMDLgsredgvgpASFWSISLLRIIQTPAEDPHKQH 418
                      .66765556666666.56*****************************9.***********99******************************** PP

  Prenylcys_lyase 272 kvykifSkeplskeqlkkll....................ssyesvkekeWlaYPkysppetleefiLhdrlYYlnaiEsaaSamEmsaiagkN 345
                      +vyk+fS+e+l++ ++ ++l                    +s+  ++ek W++YP+++p++t+ee++L+ +++Y+++iEs++S+mE+s+++g+N
       EEA20714.1 419 YVYKVFSPEKLTARFVASVLgveipesnrngtigdisnndVSW--FHEKAWHSYPYEYPRVTFEEIKLARNIWYTSGIESFISTMETSSLMGMN 510
                      ***********************************99955555..************************************************* PP

  Prenylcys_lyase 346 vAlLaanrwkeet 358
                      vA L++n+w+++ 
       EEA20714.1 511 VAGLMTNEWHDKL 523
                      *********9875 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.7   0.0   1.2e-15   2.8e-12       1      67 [.      44     117 ..      44     118 .. 0.86

  Alignments for each domain:
  == domain 1  score: 46.7 bits;  conditional E-value: 1.2e-15
                    EE--SHHHHHHHHHHHC....CTE..EEEEE-SSSSSSGGG-EECE...TTCEECTS---EEETTHHHHCHHHHCC CS
  NAD_binding_8   1 IvGaGlsGlvaAylLak....agf..dvlllekrdrlGGraasyev...pgvrvdygahifhgsgyypnvrrllre 67 
                    I+GaG +G+++Ay+L+k    ag+  +++++e+  ++GGr+++++v   p  ++++ga+if ++  ++n+++  +e
     EEA20714.1  44 IIGAGSAGASTAYYLRKfsdlAGVpiNITVFEREAYIGGRSTTVDVfddPSLPIELGASIFVSV--NHNLMDTTKE 117
                    9***************98755466669*****************9986566**********997..5888876665 PP

>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.5   0.0   2.4e-14   5.4e-11       2     277 ..      50     338 ..      49     359 .. 0.71

  Alignments for each domain:
  == domain 1  score: 42.5 bits;  conditional E-value: 2.4e-14
                    HHHHHHHHHHHTT......EEEEEEESSSSSBTTS-EEEET...TEEEESS--EEETTTHHHHHHHHHTTCCCCEE...EESCC.......GCEEE CS
  Amino_oxidase   2 aGLaaArqLlsaG......fdVtvlEardrvGGRirtvrsd...GylielGamwftgagnpllellkelgledsls...lpdpg.......apkrv 78 
                    aG ++A++L  +        ++tv+E +  +GGR  tv      + +ielGa++f   +++l    kelgl+ s      p+++         + +
     EEA20714.1  50 AGASTAYYLRKFSdlagvpINITVFEREAYIGGRSTTVDVFddpSLPIELGASIFVSVNHNLMDTTKELGLKVSGAgsdRPEDSihmlgiwDGFSF 145
                    6668899996666666688******************99887889***************************988754433333444444444444 PP

                    EETTEECC..........TTEECHHHHHHHHHHHHHHHH.CHHHHHHHHHHHHHHHHH.............HHHCCCCHHHHHHHHHCHHHHHHHH CS
  Amino_oxidase  79 lskggref..........pgdlspvpaewealleqgals.aellsleeklrlgleall.............qktldeldldskslaesleelgrre 150
                    ++++g+            +                      +++++++  + +++ +l             ++t + l l + + ++ +++l  ++
     EEA20714.1 146 IYMQGHSLswwdmtkllwR-------------------YgLAPIRTQSLMKSTVNKFLemykppyfpfsslSSTVEALGLHKATALTGVQFLKTNG 222
                    4444444444444433331...................0322233333333333333333334444444777889999999999999999999999 PP

                    HHHHHHHHHHHHHHHHHHHHHHHHCHTSTTTTCBHHHHTCCCCHHHHHTSCCCEETTHTHHHHHHHHHTTTTEEEETSEEEEEEEEETTC..EEEE CS
  Amino_oxidase 151 pgdvevwdrliepelfaklefasglfagdpselsaklalpllwelegfggslllprgGlsqlpealaeelrgldirlntrVkeikregdg..vtvt 244
                     ++    + +i          + ++ +++    +++l + l+  +++  ++ + +++G  ++   + + +++ ++ ln+ V+ ik+++d+  +   
     EEA20714.1 223 ISE-SFSNEIIQS--------STRV-NYG---QNLGLIHGLEAMVCMATDGAVAIEDGNWRIFSGMLD-SSRAEVTLNSTVTAIKQNNDEslILSY 304
                    999.888888883........3333.222...367778888888888888888888888888888888.8888*************7777667777 PP

                    ETTSTEE...EESEEEE-S-HHHHHSSEEESCCSHH CS
  Amino_oxidase 245 ledgevv...eaDaVvvTvplgvlkailfsPplpde 277
                     ++g+++    +D Vv+++p+   + i+ sP+l   
     EEA20714.1 305 SSNGDSIssrVFDEVVIAAPFQYSN-IEVSPSLE-R 338
                    7799999******************.*****882.2 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.9   0.3   3.1e-09   6.9e-06       2      37 ..      42      84 ..      41      87 .. 0.81

  Alignments for each domain:
  == domain 1  score: 25.9 bits;  conditional E-value: 3.1e-09
                EEEECTSHHHHHHHHHHHHT.....T....EEEEESSSSTTSSGG CS
         DAO  2 vviiGGGiiGlstAyeLarr.....g....VtllekgdiagsgaS 37
                ++iiG+G +G+stAy+L r+     g    +t++e++  +g g S
  EEA20714.1 42 IAIIGAGSAGASTAYYL-RKfsdlaGvpinITVFEREAYIG-GRS 84
                9****************.4334333599*********9999.544 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   1.5e-06    0.0035      14      55 ..      36      82 ..      31      88 .. 0.81
   2 ?   -2.1   0.0      0.79   1.8e+03     190     232 ..     483     526 ..     477     527 .. 0.67

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 1.5e-06
                HHTEEEEEEE--SHHHHHHHHHHHHCTTS.....-EEEEESSSS--T CS
        Thi4 14 kyaesDvvivGaGssGLtaayylakkpdl.....kvailersvspGG 55
                + +  +++i+GaGs+G ++ayyl k  dl     +++++er+  +GG
  EEA20714.1 36 ETVSRNIAIIGAGSAGASTAYYLRKFSDLagvpiNITVFEREAYIGG 82
                567789*****************998776333336889999999988 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.79
                 ---ECB-HHHHHHHHH.HHECEEETTEEE-THHHHHHHT-EB-- CS
        Thi4 190 kgeksldaekaedaiv.kktrevvpnlyvaGmevaevdganRmG 232
                 k  + ++   + ++ +       + ++ vaG+ ++e ++  ++G
  EEA20714.1 483 KLARNIWYTSGIESFIsTMETSSLMGMNVAGLMTNEWHDKLQLG 526
                 55566666666555552334556789999999999998876666 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.3   0.0   2.7e-05     0.061       1      40 [.      43      83 ..      43      92 .. 0.88
   2 ?    0.8   0.0       0.2   4.4e+02     120     152 ..     285     322 ..     271     324 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 2.7e-05
  NAD_binding_9  1 aivGaGprGlavlerLlara.kkkspleitlfdpsep.gagr 40
                   ai+GaG +G++++  L + +   + p++it+f+++ + g gr
     EEA20714.1 43 AIIGAGSAGASTAYYLRKFSdLAGVPINITVFEREAYiG-GR 83
                   8*************9999988889**********77735.65 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.2
  NAD_binding_9 120 hraevvdleeradgqavll..adgas...laadaVvLA 152
                    ++++v+++++++d+  +l   ++g+s     +d+Vv+A
     EEA20714.1 285 LNSTVTAIKQNNDESLILSysSNGDSissRVFDEVVIA 322
                    5899********99866665556654222589999998 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0     2e-05     0.044       2      30 ..      41      75 ..      40     101 .. 0.78
   2 ?   -1.8   0.0      0.66   1.5e+03     199     216 ..     282     300 ..     262     330 .. 0.62

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 2e-05
                 SEEEE--SHHHHHHHHHHHH......HTS-EEEEE CS
                 xxxxxxxxxxxxxxxxxxxx......xxxxxxxxx RF
  Pyr_redox_2  2 dvvviGgGpAGlaaaltlaq......agakvtlve 30
                 ++++iG+G AG ++a +l++        +++t++e
   EEA20714.1 41 NIAIIGAGSAGASTAYYLRKfsdlagVPINITVFE 75
                 799*****************877633355666664 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.66
                  EEEESCEEEEEEETTE.EE CS
                  xxxxxxxxxxxxxxxx.xx RF
  Pyr_redox_2 199 evklgtsvkeidgnge.kl 216
                  ev l+++v++i++n++ +l
   EEA20714.1 282 EVTLNSTVTAIKQNNDeSL 300
                  5666777777777766322 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   0.0    0.0028       6.2       1      35 [.      41      81 ..      41      88 .. 0.82
   2 ?    2.7   0.0     0.085   1.9e+02      55      75 ..     281     299 ..     270     308 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0028
                EEEEECSSHHHHHHHHHHHHTT......SEEEEEESSSSSS CS
   Pyr_redox  1 kvvvvGgGyiglElAgalaelg......kkVtvversdkll 35
                +++++G+G  g   A +l+++        ++tv+er+  + 
  EEA20714.1 41 NIAIIGAGSAGASTAYYLRKFSdlagvpINITVFEREAYIG 81
                589***************98875556666899999987765 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.085
                 EEEECSEEEEEEEEETTSEEE CS
   Pyr_redox  55 ievllntkveeiegsedgves 75 
                  ev ln++v++i++++d+  s
  EEA20714.1 281 AEVTLNSTVTAIKQNNDE--S 299
                 6899***********996..3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (542 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       298  (0.0166211); expected 358.6 (0.02)
Passed bias filter:                      279  (0.0155614); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.45
# Mc/sec: 3598.51
//
Query:       EEA20715.1  [L=316]
Description: hypothetical protein PMAA_045380 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-21   77.3  13.8    1.3e-21   77.3  13.8    2.5  3  HsbA      Hydrophobic surface binding protein A
  ------ inclusion threshold ------
          1    8.9   7.2        1.8    8.1   7.2    1.4  1  EVI2A     Ectropic viral integration site 2A protein (EVI2A)


Domain annotation for each model (and alignments):
>> HsbA  Hydrophobic surface binding protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.3  13.8   1.4e-25   1.3e-21       2     119 ..      37     150 ..      36     151 .. 0.97
   2 ?   -0.3   2.3      0.15   1.4e+03      39      80 ..     166     208 ..     155     215 .. 0.81
   3 ?   -3.3   0.1       1.3   1.2e+04      17      36 ..     282     303 ..     279     311 .. 0.64

  Alignments for each domain:
  == domain 1  score: 77.3 bits;  conditional E-value: 1.4e-25
                 HHHHHHHHHHHHHHHHHHHHHHH--SH..HHHHHHHHHHHHHHHHHHHHHHHTS----HHHHHHHHHHHHHCHHHHHHHHHHHHHTHHHHHHHT-HHHH CS
        HsbA   2 atvisdittistavtaldtavnafnGgasalpilsasnalvsaikkattdaqasapltdeealalaqavqtLepdvkaaldaliaKkpafdkagltslv 100
                 a++ s+i  i+++v++ld++v+a  G+  + ++ls+s++lvs+i+++t+++qas+ l+ ++al+la+ ++tL ++v++++++li   +a+++agl s++
  EEA20715.1  37 ASIESVIGGITKQVNQLDSDVKA--GS--LDAVLSDSTSLVSTINAGTKAVQASDDLSTSDALDLANFIGTLITAVNTTVTDLIGVSSAVQSAGLVSTI 131
                 799********************..45..88******************************************************************** PP

                 HHHHHHHHHHHHHHHHHHH CS
        HsbA 101 lssLqdlkaasdaLsdalv 119
                 l++L d+ +as aL+da++
  EEA20715.1 132 LTNLHDQYTASGALADAIT 150
                 *****************96 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.15
                 HHHHHHHHHHHHHHHTS----HHHHHHHHHHHH.HCHHHHHHH CS
        HsbA  39 nalvsaikkattdaqasapltdeealalaqavq.tLepdvkaa 80 
                 + +++++++++++ ++ +  + + ++++ ++++ t +p+ +++
  EEA20715.1 166 AYITTSLQAGIDHYSSLPATSTTPSTSVGSSTSaTSAPTSPDT 208
                 5688999999999999999999999999998886666666555 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 1.3
                 HHHHHHHH--S.H...HHHHHH CS
        HsbA  17 aldtavnafnG.g.asalpils 36 
                 +  t+v +++G +  ++l+i s
  EEA20715.1 282 KTGTSVPTYTGaAsVNGLNIAS 303
                 5667888888864455565554 PP

>> EVI2A  Ectropic viral integration site 2A protein (EVI2A)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   7.2    0.0002       1.8       8     112 ..     160     264 ..     154     272 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0002
       EVI2A   8 lhlafllttifsllpqtkanytelwavnetawdsiiqnktngrnksensntnpvtpevdkkskstetletetsspsvslapkseeelttps.vvrnsss 105
                 l + + + +  sl  ++   y +l+a+++t + s+   +++++  +   +t+pvt+   +   +t+t++++  sp++s +  s+    tp  v ++s+ 
  EEA20715.1 160 LSAQLAAYITTSLQAGID-HYSSLPATSTTPSTSVGSSTSATSAPTSPDTTSPVTTSPTTAPDTTSTPASASGSPTTSPSGASTGPSGTPVgVSPSSTA 257
                 556667777888888886.6999************99999999999999**********************99************99999966666666 PP

       EVI2A 106 ttqsten 112
                    +++ 
  EEA20715.1 258 VPGGVKP 264
                 6555543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (316 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       888  (0.0495287); expected 358.6 (0.02)
Passed bias filter:                      382  (0.0213063); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.33s 00:00:00.92 Elapsed: 00:00:00.46
# Mc/sec: 2044.31
//
Query:       EEA20716.1  [L=173]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-27   96.1  10.6    1.9e-27   96.1  10.6    1.6  2  HsbA      Hydrophobic surface binding protein A


Domain annotation for each model (and alignments):
>> HsbA  Hydrophobic surface binding protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   96.1  10.6     1e-31   1.9e-27       3     119 ..      26     143 ..      25     144 .. 0.98
   2 ?   -1.6   0.1      0.19   3.4e+03      38      52 ..     154     168 ..     150     172 .. 0.61

  Alignments for each domain:
  == domain 1  score: 96.1 bits;  conditional E-value: 1e-31
                 HHHHHHHHHHHHHHHHHHHHHH--SH...HHHHHHHHHHHHHHHHHHHHHHHTS----HHHHHHHHHHHHHCHHHHHHHHHHHHHTHHHHHHHT-HHHH CS
        HsbA   3 tvisdittistavtaldtavnafnGg.asalpilsasnalvsaikkattdaqasapltdeealalaqavqtLepdvkaaldaliaKkpafdkagltslv 100
                 +v +d++t+ ++v ald++++++nG+ ++alp+l+++n+l+++ik+attd+++sa + d+++++ a+++q+L + + ++l +l+aK p+  ++gl+++v
  EEA20716.1  26 SVLTDLETVYSKVAALDSDITSWNGQlLTALPLLTDVNTLETDIKTATTDTNNSAAFGDADSASTATEMQSLSTLIVTTLGDLVAKEPKAAAIGLKGTV 124
                 689**********************9999********************************************************************** PP

                 HHHHHHHHHHHHHHHHHHH CS
        HsbA 101 lssLqdlkaasdaLsdalv 119
                  ssL++lk++sd+L+ al 
  EEA20716.1 125 ESSLKQLKTLSDSLISALE 143
                 ****************996 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.19
                 HHHHHHHHHHHHHHH CS
        HsbA  38 snalvsaikkattda 52 
                 ++++ ++i++a ++a
  EEA20716.1 154 ATSVAATIDSAFATA 168
                 556666666666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (173 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       528  (0.0294495); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.20s 00:00:00.58 Elapsed: 00:00:00.35
# Mc/sec: 1479.09
//
Query:       EEA20717.1  [L=1366]
Description: UDP-glucose:sterol glycosyltransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.7e-33  112.6   0.5    4.2e-21   75.0   0.0    3.4  3  GRAM             GRAM domain
    9.1e-27   93.8   0.0    1.7e-26   92.9   0.0    1.5  1  Glyco_transf_28  Glycosyltransferase family 28 N-terminal dom
    1.6e-15   57.5   1.4      3e-14   53.4   0.1    3.2  4  PH               PH domain
    8.7e-05   22.7   0.1    0.00026   21.2   0.1    1.8  2  PH_8             Pleckstrin homology domain
    0.00027   21.3   0.8    0.00027   21.3   0.8    3.0  2  PH_11            Pleckstrin homology domain
    0.00064   18.6   0.0     0.0013   17.7   0.0    1.4  1  UDPGT            UDP-glucoronosyl and UDP-glucosyl transferas
    0.00071   19.7   0.0     0.0014   18.7   0.0    1.4  1  PH_3             PH domain
  ------ inclusion threshold ------
      0.067   13.6   0.0       0.22   11.9   0.0    1.9  1  PH_9             Pleckstrin homology domain
       0.19   11.7   0.1        3.2    7.8   0.0    2.4  2  GnsAB_toxin      GnsA/GnsB toxin of bacterial toxin-antitoxin
        8.2    5.0  10.6        4.8    5.8   1.9    2.2  2  Ndc1_Nup         Nucleoporin protein Ndc1-Nup


Domain annotation for each model (and alignments):
>> GRAM  GRAM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.6   0.0   4.1e-08   7.3e-05       4      57 ..     249     299 ..     246     317 .. 0.86
   2 !   11.4   0.1   0.00012      0.22      41     110 ..     392     464 ..     390     468 .. 0.78
   3 !   75.0   0.0   2.3e-24   4.2e-21       2     107 ..     698     801 ..     697     807 .. 0.95

  Alignments for each domain:
  == domain 1  score: 22.6 bits;  conditional E-value: 4.1e-08
                 HHHS----TT--EEEEEEEEEESS.SEEEEEEEEESSEEEEEE-STT---EEEE CS
        GRAM   4 rkkfkellpeEkllatykCyllrdggpvqGrlyltnyrlcFrskplgsskkvvl 57 
                 +++f+ + + E ++ +y C l+++ +  qG +y+t+ ++cF+   ++ s  v +
  EEA20717.1 249 KEIFG-FENPEPVIGEYPCWLMQN-VALQGYMYITEGHICFYAYLPQKSN-VAV 299
                 78899.9999**************.*****************99987775.444 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00012
                 EEEEEE-STT---EEEEEGGGEEEEEE....-TT-TT-EEEEESS-.....EEEEE--TTHHHHHHHHHHHHH CS
        GRAM  41 rlcFrskplgsskkvvlpladikriekstsaanllengiqvetsskdl...elaFagfvtrdeaiefieellk 110
                 +++Frs++ g  +k+ lpl+d+ +ie s+  +   + +i+v  + +     e  F+ f   ++a+e++++l++
  EEA20717.1 392 KVIFRSQNEGGRVKISLPLEDVIDIEESPMMDLAQTFKIRVVDIYETYaidEHFFSFFNFGQDAFEVLKDLIN 464
                 89*************************7777766666666655555444577788888888888888888876 PP

  == domain 3  score: 75.0 bits;  conditional E-value: 2.3e-24
                 HHHHHS----TT--EEEEEEEEEESS.SEEEEEEEEESSEEEEEE-STT---EEEEEGGGEEEEEE....-TT-TT-EEEEESS-..EEEEE--TTHHH CS
        GRAM   2 lfrkkfkellpeEkllatykCyllrdggpvqGrlyltnyrlcFrskplgsskkvvlpladikriekstsaanllengiqvetsskdlelaFagfvtrde 100
                 +fr++f  l+p Ekl aty+ yl+r  +p +G++y+ n++ cFrs+ +g+ +k++lp++di+++ek+++ +  +++++ ++ ++++l ++F+   +rd+
  EEA20717.1 698 RFRAHFA-LPPTEKLQATYYGYLHRV-LPLYGKIYIGNSKFCFRSLLPGTRTKMILPIKDIENVEKEKGFRFGYQGLVLIIRGHEELFFEFNTADSRDD 794
                 69*****.****************99.***********************************************************************9 PP

                 HHHHHHH CS
        GRAM 101 aiefiee 107
                 +  ++ +
  EEA20717.1 795 CAVTLHH 801
                 9766665 PP

>> Glyco_transf_28  Glycosyltransferase family 28 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.9   0.0   9.7e-30   1.7e-26       1     139 []     870    1005 ..     870    1005 .. 0.91

  Alignments for each domain:
  == domain 1  score: 92.9 bits;  conditional E-value: 9.7e-30
                       EEEEE-SSHHHHHHHHHHHHHHHCTT-EEEEEEETCCCHHHHHHCCT-EEEE---G..HCTT..CHHHHCCHHHHHHHHHHHHHHHHHHHHC CS
  Glyco_transf_28    1 ivllggGTgGhvfPalAlakeLkkegheVrylgtkrgleerlveeaglefepiage..klrrklspknlkeilkvlkavvkakkilkeakpd 90  
                       i+ l++G++G+v+P++ l k+L +egh+ + ++t++++e ++ +++g+ f p++g+  +l+r + ++n   + ++lk+    ++ ++++ ++
       EEA20717.1  870 ITCLTIGSRGDVQPYIGLCKGLLAEGHRPK-IATHAEFEPWV-RQHGIDFAPVEGDpaELMR-ICVENGMFTYSFLKEASSKFRGWIDDLLT 958 
                       5779**************************.**********9.*************995555.5555555566666666666********** PP

                       CCCCCCCCCCHCCCCCHCCCTTHCCCCCHCTS-ECCCCCCCCC-SCCCE CS
  Glyco_transf_28   91 avvgtggyvslpaviaaplaripviihEqnaipglanktlsrtatkvai 139 
                         + ++  ++ +++i++p+a+++++i+E++ ip+++ +t+++ +t++++
       EEA20717.1  959 SAWNAC--QDSDVLIESPSAMAGIHIAEALRIPYFRGFTMPWSRTRAYP 1005
                       ******..9*************************************996 PP

>> PH  PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.4   0.1   1.7e-17     3e-14       2     104 ..     299     394 ..     298     395 .. 0.92
   2 ?   -2.0   0.0       2.8   5.1e+03      45      75 ..     405     433 ..     397     448 .. 0.78
   3 ?   -3.3   0.1       7.5   1.3e+04      40      73 ..     495     528 ..     482     540 .. 0.58
   4 ?    1.1   0.0      0.31   5.5e+02      43      95 ..     746     794 ..     729     799 .. 0.71

  Alignments for each domain:
  == domain 1  score: 53.4 bits;  conditional E-value: 1.7e-17
                 EEEEEEEEETSSSSCSEEEEEEEEETTEEEEESSTTCTTESSEEEEEESTTEEEEEEECTTSSSSTSEEEEEESTSSSTEEEEEEESSHHHHHHHHHHH CS
          PH   2 vkeGwLlkkgsgkkkswkkrwfvLkdsellyykndksekdkepkgsislsncevvevvatedpkrkfcfelriverngsrtyllqasseeerkeWikai 100
                 vk+G L+k+g ++  ++k++wf Lk+++++yy+++  +k + p g i+l+   + +  ++e++k    f ++++    +r+y+++a+s+++++eW+ka+
  EEA20717.1 299 VKSGQLSKRGRKNP-RYKRYWFSLKGDVFSYYEDP--SKLYFPSGHIDLRYGISASLADKEKGKDTRDFTVTTD----QRSYFFRADSASSANEWVKAL 390
                 799***********.********************..9************999999865668888888888777....69******************* PP

                 HHHH CS
          PH 101 qsai 104
                 q++i
  EEA20717.1 391 QKVI 394
                 *997 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 2.8
                 EEEEESTTEEEEEEECTTSSSSTSEEEEEES CS
          PH  45 kgsislsncevvevvatedpkrkfcfelriv 75 
                 k s++l+++ + e+  +++++   +f++r+v
  EEA20717.1 405 KISLPLEDVIDIEE--SPMMDLAQTFKIRVV 433
                 66889999999987..89**********988 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 7.5
                 TESSEEEEEESTTEEEEEEECTTSSSSTSEEEEE CS
          PH  40 kdkepkgsislsncevvevvatedpkrkfcfelr 73 
                 ++ + k   +l++ + ++ +++++  +  +f+  
  EEA20717.1 495 SSASEKPDANLESSSAQKSETSDQNHESDSFVQS 528
                 4555566666666666665545555555555554 PP

  == domain 4  score: 1.1 bits;  conditional E-value: 0.31
                 SEEEEEESTTEEEEEEECTTSSSSTSEEEE.....EESTSSSTEEEEEEESSHHHHHH CS
          PH  43 epkgsislsncevvevvatedpkrkfcfel.....riverngsrtyllqasseeerke 95 
                 + k++++++++e ve     +++ +    +     ++  r++ ++++++++++++r +
  EEA20717.1 746 RTKMILPIKDIENVEK----EKGFR----FgyqglVLIIRGH-EELFFEFNTADSRDD 794
                 5667777777777753....33333....2334445555677.**********99975 PP

>> PH_8  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.1   1.5e-07   0.00026       3      88 ..     304     393 ..     302     394 .. 0.81
   2 ?   -3.2   0.0       5.8     1e+04      57      84 ..     928     955 ..     923     957 .. 0.82

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 1.5e-07
        PH_8   3 llkkrrkklqgyakRfFvLdlksstlsYyrddnss.......alrgkiplslaiisaneekreiiidsGaevWeLkasnekdfqeWvealeka 88 
                 l k+ rk +  y++ +F+L  k    sYy+d  +         lr  i+ sla  +  +++r++++ +  + +  +a++++ ++eWv+al+k+
  EEA20717.1 304 LSKRGRK-NPRYKRYWFSL--KGDVFSYYEDPSKLyfpsghiDLRYGISASLADKEKGKDTRDFTVTTDQRSYFFRADSASSANEWVKALQKV 393
                 5666665.55689999999..99999****986544444555677777777777888899******************************986 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 5.8
        PH_8  57 reiiidsGaevWeLkasnekdfqeWvea 84 
                  +i ++ G+  ++   + +++f+ W++ 
  EEA20717.1 928 MRICVENGMFTYSFLKEASSKFRGWIDD 955
                 5688999999999999999999999875 PP

>> PH_11  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.8   1.5e-07   0.00027       7     104 ..     306     392 ..     300     393 .. 0.79
   2 ?   -2.9   0.3       5.3   9.6e+03      46      75 ..     496     525 ..     481     540 .. 0.55

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 1.5e-07
       PH_11   7 kkgsk..aWkrrwfavlkdgvLeyYksekkkvvkhviklSngseaklkadlisaalfkidsirssksddllleistetkifflkgdsneeteeWvealk 103
                 k+g k   +kr+wf  lk  v++yY+++ k +       S  ++ +++ +++ a       ++ + +d  ++++ t+++ +f+++ds    +eWv+al+
  EEA20717.1 306 KRGRKnpRYKRYWF-SLKGDVFSYYEDPSKLY-----FPSGHIDLRYGISASLA-------DKEKGKDTRDFTVTTDQRSYFFRADSASSANEWVKALQ 391
                 555556679*****.***************99.....45555555555555544.......444567788999*************************9 PP

       PH_11 104 e 104
                 +
  EEA20717.1 392 K 392
                 7 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 5.3
       PH_11  46 gseaklkadlisaalfkidsirssksddll 75 
                 + + k  a+l s +++k + +  ++++d +
  EEA20717.1 496 SASEKPDANLESSSAQKSETSDQNHESDSF 525
                 344444455555555555555555554444 PP

>> UDPGT  UDP-glucoronosyl and UDP-glucosyl transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0     7e-07    0.0013     213     386 ..    1047    1234 ..    1014    1251 .. 0.70

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 7e-07
       UDPGT  213 lgrpvtlaellskaevwllrsyfdlefPrpl.lpnvefigg...lnckpakplpkeleefvqssGehG..vvvfSlGsmvseipeekanaiAsaLak 303 
                  lg  +t+ + +++ +v +l +y +   P pl  p+   ++g   ln +     p+el +f++ + e+G  +v++ +Gs+v   p    ++i ++++k
  EEA20717.1 1047 LGLRGTTLDKMQANKVPFLYNYSPSVVPPPLdYPDWIRVTGywfLNEASSWTPPTELVNFIKKTREDGkkIVYIGFGSIVVSDPAALTRTIVESVQK 1143
                  5555666666666666666666666666665345555555522234444445588999999999998888999999999999999999999999999 PP

       UDPGT  304 ipqkvl....WrfdgkkPstLakntllvkWlPqndlLgH....PktkAFvtHaGangvyEaisnGvPmvglPlFgdqrdNikrmeakgaav 386 
                     + +    W+ +   P+   +   l   + q +   H     ++ A v H+Ga +   ++  GvP ++ P+Fgdq     r+e  g ++
  EEA20717.1 1144 ADVRCIlskgWSDRLGDPKSTRSEVPLPAEIHQIQSAPHdwlfTQIDAAVHHGGAGTTGASLRAGVPTIIKPFFGDQFFFGSRIEDLGVGI 1234
                  98877646667767678888888887766676666666622224789******************************98877777777665 PP

>> PH_3  PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   7.6e-07    0.0014      10      98 ..     295     393 ..     288     399 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 7.6e-07
        PH_3  10 gelilkqgivkKr..kglfarkRqllltdgPrLiyvDpekmekk.GeIplskelkv......evknskkFlihtpkrtyyled.pegnaakWvkaieev 98 
                  +  +k+g + Kr  k+   ++ ++ l      +y Dp+k     G+I l   +++      + k+ ++F + t++r y +   + + a++Wvka+++v
  EEA20717.1 295 SNVAVKSGQLSKRgrKNPRYKRYWFSLKGDVFSYYEDPSKLYFPsGHIDLRYGISAsladkeKGKDTRDFTVTTDQRSYFFRAdSASSANEWVKALQKV 393
                 567889999999975555688999999999888899999888755999888555441111115578899************7549999*********98 PP

>> PH_9  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   0.00013      0.22      22     114 ..     310     390 ..     294     393 .. 0.61

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00013
        PH_9  22 kkrgWkevyavlkklvLylykdeeesesaetedlkslknakllgkirlhhaLaekasdYkkkshvFrLqtadgaeylfqtsdakevqeWvdti 114
                 k+  +k  +  lk++v+  y+d  +s+ + ++   +        +  ++++La k ++   +   F + t d+++y+f + +a  ++eWv+++
  EEA20717.1 310 KNPRYKRYWFSLKGDVFSYYED--PSKLYFPSGHID-------LRYGISASLADKEKGKDTR--DFTV-TTDQRSYFFRADSASSANEWVKAL 390
                 5555555555566666655555..222222222122.......2233555555555543333..4666.5699*****************987 PP

>> GnsAB_toxin  GnsA/GnsB toxin of bacterial toxin-antitoxin system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0      0.26   4.6e+02      24      42 ..     108     126 ..     103     129 .. 0.81
   2 ?    7.8   0.0    0.0018       3.2      21      36 ..     583     599 ..     578     602 .. 0.81

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.26
                  HHHHHHSSEEEEEEEEEEE CS
  GnsAB_toxin  24 ELkKkTGkEVseieFtaRE 42 
                   L  +TGkE s+ +  + E
   EEA20717.1 108 RLSNRTGKELSSSQVIPEE 126
                  58899******98877766 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0018
                  HH.HHHHHHHSSEEEEE CS
  GnsAB_toxin  21 Ki.aELkKkTGkEVsei 36 
                  K+ aE  KkTGkEVs +
   EEA20717.1 583 KVlAEPTKKTGKEVSRV 599
                  443899********975 PP

>> Ndc1_Nup  Nucleoporin protein Ndc1-Nup
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   1.9    0.0027       4.8     366     474 ..     126     251 ..     103     326 .. 0.65
   2 ?    4.0   1.7    0.0092        16     309     443 ..     424     586 ..     421     663 .. 0.49

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0027
    Ndc1_Nup 366 pknkasapvkelprlsksplkkk.ddeifgn.sltaeaspkssssskegvekalsslakspgqspsptarls..................prarkllek 444
                 ++ +++ p+++ +++s ++++ + +     n  l++ +s  ++++ keg  ++++++a+sp+++++p+++ s                  + ++ +l++
  EEA20717.1 126 EAGQEARPSRKPSTSSVNSHRRTgSG----NrLLRSIPSIVPKRNDKEGKPDQVTQAAQSPQDESQPAQETSkttprtapilsrmieaqtRFDPAALST 220
                 22222333333333333333333322....223334455556666677777777777777777766666666666777777777777777777777777 PP

    Ndc1_Nup 445 aksrllskeqkealsestikkkvekelaq.l 474
                 ++ ++ +ke++ ++s+++ +k + +++++ +
  EEA20717.1 221 EEHAQAEKEADDKQSDEQKSKLLLPIRLKeI 251
                 7888877777777777777666555554444 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.0092
    Ndc1_Nup 309 iaqsspsrRkaIFsdidrkggs.tWsqilkeClklikeltqrinergq.papkaapskapknkasapvkelprlsksplkkkddeifgn..sltaeasp 403
                 +aq+++ r   I+++   +++   +  + + +++++k+l +  ++r   + p+a++        ++ v+e++r+ ++++ +  ++  +n  s++a++  
  EEA20717.1 424 LAQTFKIRVVDIYETYAIDEHFfSFFNFGQDAFEVLKDLINDSTARRIaQDPAATQ------VLNEVVSESYRQRADSSAS--EKPDANleSSSAQK-- 512
                 78888888888888888888878888888889999999777666666623333333......2333333333333222222..11111111111111.. PP

    Ndc1_Nup 404 kssssskegvekalsslakspgqspsptarls.........................................prarklle 443
                     s +++ +   +s+ +s gq+    ++ls                                           ark+l 
  EEA20717.1 513 ----SETSDQNHESDSFVQSIGQT---ESSLSlqshpdtivtasqiltrddvfnsptihslrpntslegvsfeHPARKVLA 586
                 ....12222222223333333333...122222112222222223333333333333333344444555555533444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1366 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       769  (0.0428914); expected 358.6 (0.02)
Passed bias filter:                      402  (0.0224218); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.88u 0.35s 00:00:01.23 Elapsed: 00:00:00.49
# Mc/sec: 8399.62
//
Query:       EEA20718.1  [L=471]
Description: serine hydroxymethyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   3.6e-208  691.0   0.0   4.1e-208  690.8   0.0    1.0  1  SHMT             Serine hydroxymethyltransferase
     0.0063   15.8   0.0      0.011   15.0   0.0    1.5  1  Beta_elim_lyase  Beta-eliminating lyase
  ------ inclusion threshold ------
       0.13   10.8   0.1       0.32    9.5   0.0    1.6  2  Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
       0.16   11.3   0.0       0.44    9.9   0.0    1.6  2  Baculo_DNA_bind  ssDNA binding protein


Domain annotation for each model (and alignments):
>> SHMT  Serine hydroxymethyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  690.8   0.0  9.2e-212  4.1e-208       1     399 []      18     417 ..      18     417 .. 1.00

  Alignments for each domain:
  == domain 1  score: 690.8 bits;  conditional E-value: 9.2e-212
                 HHHHTHHHHHHHHHHHHHHHHSEE-STT-----HHHHHHHTSGGGG----EETTEESSST-HHHHHHHHHHHHHHHHHCT-STTTEEEE---SSHHHHH CS
        SHMT   1 leesdpevaeiikkekerqkeeieliasenftskavlealGsvltnkyaeGyPGkryyGGcefvdeveelaqdrakelfkldpakwgvnvqplsGsqan 99 
                 l++ dpe+aeiikke +rq+e+i liasen+ts+av++alG+ ++nky+eGyPG+ryyGG++++d ve  +q+ra+++f+ldp+kwgvnvq+lsGs+an
  EEA20718.1  18 LADFDPEIAEIIKKEIQRQRESILLIASENVTSRAVFDALGTPMSNKYSEGYPGARYYGGNQHIDAVELTCQARALKVFNLDPEKWGVNVQTLSGSPAN 116
                 5789*********************************************************************************************** PP

                 HHHHHHHT-TT-EEEEESCTTTSTGGGT-BTSS-B-SHHHHHSEEEEE-B-TTTSSB-HHHHHHHHHHH--SEEEEE-SST-S---HHHHHHHHHHTT- CS
        SHMT 100 lavytallepgdrilgldladGGhlthGakveskkisassklfesveykvdketglidydelekkakefkPklivaGtsaysrlidyarlreiadevga 198
                 l+vy+al++p+dr++gldl++GGhl+hG+++ ++kisa+s++fe+++y+v++etg+idyd+le +a++++Pk++vaGtsay+rlidyar+r+iad+vga
  EEA20718.1 117 LQVYQALMKPHDRLMGLDLPHGGHLSHGYQTPQRKISAVSTYFETFPYRVNSETGIIDYDTLEANAQLYRPKILVAGTSAYCRLIDYARMRKIADSVGA 215
                 *************************************************************************************************** PP

                 EEEEE-GGGHHHHHTTSS--GCCTSSEEEEESSSTT-S-S-EEEEEC-SEEEEE.TTTEEEEHHHHHHHHHHHTTTT-SS--HHHHHHHHHHHHHCTSH CS
        SHMT 199 yllvdmahiaGlvaagvipsPfeyadvvtttthktlrGprgglillrkgvksvd.ktgkevleelekkinsavfPglqGGPlnhviaakavalkealep 296
                 yl+vdmahi+Gl+aagvipsPfeyadvvtttthk+lrGprg++i++rkgv+s d ktgke+l++le  in++vfPg+qGGP+nh+i+a+avalk+a +p
  EEA20718.1 216 YLVVDMAHISGLIAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFFRKGVRSTDpKTGKEILYDLEGPINFSVFPGHQGGPHNHTITALAVALKQASTP 314
                 *************************************************************************************************** PP

                 HHHHHHHHHHHHHHHHHHHHHHTT-EEGGGS-SSSEEEEEGGGGTS-HHHHHHHHHHTTEE-EEE--TTSSTTTT-SEEEEESHHHHHTT--HHHHHHH CS
        SHMT 297 efkvyqkqvlknakalaealkekgyklvsgGtdnhlvlvdlrekgldGkraekvlekvnitankntvPgdksalvtsGlrlGtpaltsrgfkeedlekv 395
                 ef++yq+q +knakal+ a+ke gyklv++Gtd+h+vlvdlr++g+dG+r+e+vle++ni++nkn+vPgdksal ++G+r+G+pa+t+rg++eed+++v
  EEA20718.1 315 EFRQYQEQTIKNAKALEVAFKEYGYKLVADGTDSHMVLVDLRPNGIDGARVETVLEQINIACNKNAVPGDKSALSPGGIRVGAPAMTTRGLGEEDFKRV 413
                 *************************************************************************************************** PP

                 HHHH CS
        SHMT 396 akfi 399
                 + +i
  EEA20718.1 414 VGYI 417
                 9997 PP

>> Beta_elim_lyase  Beta-eliminating lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   2.5e-06     0.011      14     216 ..      61     317 ..      55     427 .. 0.73

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 2.5e-06
                      HHHHHHCS----CCCT--HHHHHHHHHHHHHTT-SEEEE............ES-HHHHHHHHHHHH--TTEEEEEETT......-HHHHSSTTH CS
  Beta_elim_lyase  14 msdaqaaamlGdesYgedktvnrLedavaelfgkeaalf............vpqGtaAnsillkillqrgeevivtep......ahihfdetga 89 
                      ms++ ++   G   Yg+++ + ++e ++++ + k   +f            + +G  An   +++l+++++  +  +       +h++ + ++ 
       EEA20718.1  61 MSNKYSEGYPGARYYGGNQHIDAVELTCQARALK---VFnldpekwgvnvqTLSGSPANLQVYQALMKPHDRLMGLDLphgghlSHGYQTPQRK 151
                      6666677777888899999999888888885533...3333346666677799**************98777654444789999*****99999 PP

                      HHHCC--EEEEE-...EBTTTBE-HHHHHHHS--S-TTS-EEEEEEEESSBTTTTTB---HHHHHHHHHHHHHCT-EEEEEETTHHHHHHHHTS CS
  Beta_elim_lyase  90 iaelagvklrdlk...nkeaGkmdlekleaaikevgaheekiklisltvTnntagGqvvsleelrevaaiakkygiplhlDgARfanaakslge 180
                      i++++   + +++   n+e+G +d + lea  +    +++k   i+++ T  +       l   +++++ia++ g  l++D A +     + g+
       EEA20718.1 152 ISAVSTY-FETFPyrvNSETGIIDYDTLEANAQL---YRPK---ILVAGTSAY-----CRLIDYARMRKIADSVGAYLVVDMAHISGL-IAAGV 232
                      9888655.444432234455*********98888...4444...677777776.....556666777889999**********98765.58888 PP

                      -CHHHHTTSSEEEEESSSTT--SS-EEEEE-HH..................................................... CS
  Beta_elim_lyase 181 ivkemfsyvDsvtmslkKdllanvGgvlafrddel..................................................e 216
                      i++  f+y+D+vt    K l  + G++++fr+                                                      
       EEA20718.1 233 IPS-PFEYADVVTTTTHKSLRGPRGAMIFFRKGVRstdpktgkeilydlegpinfsvfpghqggphnhtitalavalkqastpefR 317
                      886.69*************************9855667777777777777776666666666666666666666666666665553 PP

>> Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.0     7e-05      0.32     145     204 ..     192     255 ..     153     262 .. 0.70
   2 ?   -3.3   0.1      0.53   2.4e+03      11      42 ..     297     328 ..     292     335 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 7e-05
                      SS-TTTT----HHHHHHHHHHTT-EEEEEGTTTHTTTS-...GGGGT.-SEEEEETTTTTTCSS CS
  Cys_Met_Meta_PP 145 tptnpllkvvDiekiaklakkagvlvvvDntfaspllqr...plklg.aDivvhSaTKylgGhs 204
                      + t+  ++++D +++ k+a ++g+ +vvD + +s+l+     p  ++ aD+v+  + K l G  
       EEA20718.1 192 AGTSAYCRLIDYARMRKIADSVGAYLVVDMAHISGLIAAgviPSPFEyADVVTTTTHKSLRGPR 255
                      45778999*********************99988876541112234359****99999999865 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 0.53
                      CHTTTTBSS--B---SBBBESSHHHHCTTCSS CS
  Cys_Met_Meta_PP  11 kdeqtgavavpiyltstykfkdvdeafageek 42 
                      ++++ +a av++ ++st +f++ +e++ +++k
       EEA20718.1 297 HNHTITALAVALKQASTPEFRQYQEQTIKNAK 328
                      34578899999999999999988887555544 PP

>> Baculo_DNA_bind  ssDNA binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0   9.9e-05      0.44      60     109 ..     178     227 ..     153     231 .. 0.88
   2 ?   -2.5   0.0       0.6   2.7e+03     126     145 ..     418     437 ..     412     443 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 9.9e-05
  Baculo_DNA_bind  60 pkspkvvyniglrvkgglkkfyffDrvkvkrakstfGeFlsvswsnipvh 109
                       +++   y+ +++v+g    + ++D+++++++  + G +l+v +++i+ +
       EEA20718.1 178 LEANAQLYRPKILVAGTSAYCRLIDYARMRKIADSVGAYLVVDMAHISGL 227
                      5578889*************************************999765 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.6
  Baculo_DNA_bind 126 deqlklqnsvlvnlPedeev 145
                      d+ +k+++s+ ++lP++ ++
       EEA20718.1 418 DQAIKISKSIQASLPKEANK 437
                      78999**********99544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (471 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       534  (0.0297841); expected 358.6 (0.02)
Passed bias filter:                      508  (0.028334); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.31s 00:00:00.94 Elapsed: 00:00:00.49
# Mc/sec: 2894.09
//
Query:       EEA20719.1  [L=210]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.6e-17   61.6   0.0    1.2e-16   60.6   0.0    1.5  1  Med9      RNA polymerase II transcription mediator complex su
      0.003   17.8   1.7      0.003   17.8   1.7    1.9  2  Med21     Subunit 21 of Mediator complex
  ------ inclusion threshold ------
      0.071   13.1   0.1       0.13   12.2   0.1    1.5  1  DUF2680   Protein of unknown function (DUF2680)
      0.071   12.9   0.2      0.097   12.5   0.2    1.2  1  DUF4515   Domain of unknown function (DUF4515)
      0.096   12.9   0.1       0.17   12.1   0.1    1.3  1  XhlA      Haemolysin XhlA
       0.18   12.2   0.1       0.18   12.2   0.1    1.7  2  Csm1_N    Csm1 N-terminal domain
       0.19   11.6   0.2       0.26   11.2   0.2    1.1  1  GP41      Retroviral envelope protein
        1.2    9.3   4.0       0.16   12.1   0.3    1.4  2  KCT2      Keratinocyte-associated gene product


Domain annotation for each model (and alignments):
>> Med9  RNA polymerase II transcription mediator complex subunit 9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.6   0.0   5.3e-20   1.2e-16      18      79 ..     133     194 ..     122     195 .. 0.94

  Alignments for each domain:
  == domain 1  score: 60.6 bits;  conditional E-value: 5.3e-20
        Med9  18 nlsskdletktgelrhkLkkarelirelpgidrsveeqeaeieeleeqlakKrelLkkyknr 79 
                  l++kdl t+++++r +++kar++++ l++++r++eeq++eieel+e++a  r + +++++r
  EEA20719.1 133 PLEAKDLLTAASAIRIRIQKARAVVQGLSDVERTTEEQDDEIEELQERIASLRGVVADFGRR 194
                 599********************************************************987 PP

>> Med21  Subunit 21 of Mediator complex
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.9      0.69   1.5e+03      34      67 ..       9      48 ..       2      57 .. 0.43
   2 !   17.8   1.7   1.4e-06     0.003      22     115 ..      88     182 ..      76     191 .. 0.70

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.69
       Med21 34 plseqdpsspsaapalakip........qeekeepepdspee 67
                 +s+q++ s+++  a +  +        ++++++++  +p++
  EEA20719.1  9 AASQQQKISSTPDVAPT--SpqvtlpapKTTPQAVPFPPPQT 48
                33333332222221111..11233433344444445555555 PP

  == domain 2  score: 17.8 bits;  conditional E-value: 1.4e-06
       Med21  22 tlgylntshdpsplseqdpsspsaapalakip.....qeekeepepdspeefaatqrelardlilkeqqIeyLIssLPgigsseeeqeerikeLeeelr 115
                 ++g+ ++ +  s+ + q++s+p+++pa++  +     +  +++p+++ p   a+ + + a+ + ++ q+ ++ ++ L +++ ++eeq+++i+eL+e ++
  EEA20719.1  88 SVGVASQTEAGSQSQ-QKQSQPQPKPASQ--QplggaT-DSATPSSNLPPLEAKDLLTAASAIRIRIQKARAVVQGLSDVERTTEEQDDEIEELQERIA 182
                 455544444444444.3333444444333..2568844.444455555555567788999***********************************9876 PP

>> DUF2680  Protein of unknown function (DUF2680)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.1     6e-05      0.13       2      20 ..     167     185 ..     166     190 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 6e-05
     DUF2680   2 TdeQkkeleaLyqqiaelr 20 
                 T+eQ +e+e+L++ ia+lr
  EEA20719.1 167 TEEQDDEIEELQERIASLR 185
                 9****************98 PP

>> DUF4515  Domain of unknown function (DUF4515)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.2   4.3e-05     0.097      66     111 ..     153     198 ..     137     207 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 4.3e-05
     DUF4515  66 lkkeLqalediaklkeqqerkiqtLeeekekvqaetaeklrelklq 111
                  +   q l d++   e+q+ +i++L+e  ++++ + a+  r++ +q
  EEA20719.1 153 ARAVVQGLSDVERTTEEQDDEIEELQERIASLRGVVADFGRRAGAQ 198
                 4556899******************************999999887 PP

>> XhlA  Haemolysin XhlA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.1   7.4e-05      0.17      20      45 ..     160     185 ..     149     188 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 7.4e-05
        XhlA  20 vdkleekaaeaeekiknleedlkkle 45 
                 ++++e+  +e++ +i++l+e++++l 
  EEA20719.1 160 LSDVERTTEEQDDEIEELQERIASLR 185
                 5799*******************997 PP

>> Csm1_N  Csm1 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.1       7.5   1.7e+04      57      64 ..      98     105 ..      91     108 .. 0.45
   2 ?   12.2   0.1   8.1e-05      0.18      32      58 ..     163     189 ..     144     199 .. 0.80

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 7.5
      Csm1_N  57 vkeleerr 64 
                  +++++++
  EEA20719.1  98 GSQSQQKQ 105
                 33333333 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 8.1e-05
      Csm1_N  32 LsqkletkdqeiesLkeqlaeleekvk 58 
                  ++++e +d+eie+L+e++a+l+  v+
  EEA20719.1 163 VERTTEEQDDEIEELQERIASLRGVVA 189
                 56889****************986665 PP

>> GP41  Retroviral envelope protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.2   0.00012      0.26       2      54 ..     142     194 ..     141     203 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00012
                 XXEXXXXTHH.HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH....... CS
        GP41   2 aaasltksvq.aatlvdglqrnvlkvleeqqeldkkleaRlsAleevvrvlged 54 
                 aa ++   +q a+ +v+gl  +v +  eeq + + +l++R+  l  vv ++g+ 
  EEA20719.1 142 AASAIRIRIQkARAVVQGL-SDVERTTEEQDDEIEELQERIASLRGVVADFGRR 194
                 6777888888355667777.589***************************9975 PP

>> KCT2  Keratinocyte-associated gene product
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.4         5   1.1e+04      16      28 ..      15      27 ..       4      37 .. 0.46
   2 ?   12.1   0.3   7.2e-05      0.16       8      95 ..      91     183 ..      84     205 .. 0.68

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 5
        KCT2 16 ekssaasaasrvs 28
                + ss++ +a+++ 
  EEA20719.1 15 KISSTPDVAPTSP 27
                2333344444433 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 7.2e-05
        KCT2   8 ttlkaptaekssaasaasrvsaassvs.....eeeadasedtsleeedlltlnsspsvikdtldnGdyGepdydlttssrdeesdeiseenre 95 
                  + ++ ++ +s++ +  +++++as+ +     + ++ +s+ + le +dllt  s+  +  +   +   G +d + tt+ +d+e +e  e   +
  EEA20719.1  91 VASQTEAGSQSQQKQSQPQPKPASQQPlggatDSATPSSNLPPLEAKDLLTAASAIRIRIQKARAVVQGLSDVERTTEEQDDEIEELQERIAS 183
                 44444445556666666777777665511110444455666779********9999988888888889*********9999888877665443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (210 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1334  (0.0744046); expected 358.6 (0.02)
Passed bias filter:                      809  (0.0451224); expected 358.6 (0.02)
Passed Vit filter:                        94  (0.0052429); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.47u 0.25s 00:00:00.72 Elapsed: 00:00:00.39
# Mc/sec: 1633.20
//
Query:       EEA20720.1  [L=520]
Description: phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-73  247.1   0.0    1.7e-73  246.7   0.0    1.2  1  iPGM_N           BPG-independent PGAM N-terminus (iPGM_N)
    6.7e-72  241.8   0.0    7.7e-72  241.6   0.0    1.0  1  Metalloenzyme    Metalloenzyme superfamily
    9.8e-06   25.4   0.0    1.6e-05   24.7   0.0    1.4  1  Phosphodiest     Type I phosphodiesterase / nucleotide pyroph
    8.1e-05   22.1   0.0    0.00012   21.5   0.0    1.4  1  Sulfatase        Sulfatase
  ------ inclusion threshold ------
      0.044   12.7   0.1       0.23   10.3   0.0    2.0  2  Alk_phosphatase  Alkaline phosphatase
       0.07   12.6   0.0       0.15   11.5   0.0    1.6  1  AP_endonuc_2     Xylose isomerase-like TIM barrel


Domain annotation for each model (and alignments):
>> iPGM_N  BPG-independent PGAM N-terminus (iPGM_N)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  246.7   0.0   5.7e-77   1.7e-73       1     214 [.      92     304 ..      92     305 .. 0.96

  Alignments for each domain:
  == domain 1  score: 246.7 bits;  conditional E-value: 5.7e-77
                 HHHHHHCTGGGG-HHHHHHHHHHHHCTSEEEEEEE-SS--SS--CHHHHHHHHHHHHTT-SEEEEEEEE-SSSSTTT-HHHHHHHHHHHHHHCT--EEE CS
      iPGM_N   1 inkaiedgslfenealkeaiekakkngkalHllGLlSdGgVHShidhllallelakeegvkkvvvhaflDGRDtapksaleyleeleeklkelgvgkia 99 
                 i+ ++++g+l e e++++ +++a + +++lHllGL+SdGgVHS+++hl+ ll++ak+ gv+kv++h+f DGRDt+pksa++y++el +k+kelg+g+++
  EEA20720.1  92 IDLTLKNGKLGEVENIRKSFQRAVDGNGRLHLLGLVSDGGVHSQNKHLYGLLQVAKDMGVPKVIIHFFGDGRDTDPKSAARYMQELLDKTKELGIGEVG 190
                 677899********************************************************************************************* PP

                 EEEEHHHHT--SS-HHHHHHHHHHHCCSSSEEECTTHHHHHHHHHHTT--GGG---EEE...TCCGGS--TT-EEEE----CCCCHHHHHHHH...STT CS
      iPGM_N 100 svsGRyyaMDRdkrwervekaydalvkgegeskaesaveaieesyakgetDefveptviaeegkkegtikdgDaviffNFRaDRareltralt...dke 195
                 +v+GRyy MDRdkrw+rve + + +++gege+ ++++v++iee+yakge+Def++p+++   g ke++++d+D+++ffN+R+DR+re+t++l    ++ 
  EEA20720.1 191 TVVGRYYVMDRDKRWDRVEIGMRGIITGEGEA-STDPVKTIEERYAKGENDEFLKPIIV---GGKENRVHDDDTLFFFNYRSDRVREITQLLGgydRSP 285
                 ****************************9987.679***********************...7899***************************773334 PP

                 HHCC.--TT-EEEESS-S- CS
      iPGM_N 196 fkefekakklklvtmteYd 214
                 + +f  +k+++++tmt+Y+
  EEA20720.1 286 IPDFPYPKNIQITTMTQYK 304
                 8888899***********8 PP

>> Metalloenzyme  Metalloenzyme superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  241.6   0.0   2.6e-75   7.7e-72       2     247 ..       7     506 ..       6     507 .. 0.97

  Alignments for each domain:
  == domain 1  score: 241.6 bits;  conditional E-value: 2.6e-75
                    EEEEEEETTBB----...GGGTTHHHS--HHHHHH...HHH........SEEEEEESSSTT----HHHHHHHH....................... CS
                    xxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxx...xxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxx....................... RF
  Metalloenzyme   2 kvvlvvlDGlGeapa...delnaihvAktPtldkL...kkeaPerw.likahgtavglpeddmgnsevgHlel....................... 67 
                    kv+l+v+DG+G+a +    e +ai  A+tP++ ++   k +  + +  ++a+ +avglpe+ mgnsevgHl++                       
     EEA20720.1   7 KVALIVIDGWGIAGPnspPEGDAIAAAETPVMSSFadpKSKTAQGYtELDASSLAVGLPEGLMGNSEVGHLNIgagrvvwqdsvridltlkngklg 102
                    89**********98855567899************8885666788999************************************************ PP

                    ................................................................................................ CS
                    ................................................................................................ RF
  Metalloenzyme  68 ................................................................................................ 67 
                                                                                                                    
     EEA20720.1 103 evenirksfqravdgngrlhllglvsdggvhsqnkhlygllqvakdmgvpkviihffgdgrdtdpksaarymqelldktkelgigevgtvvgryyv 198
                    ************************************************************************************************ PP

                    ................................................................................................ CS
                    ................................................................................................ RF
  Metalloenzyme  68 ................................................................................................ 67 
                                                                                                                    
     EEA20720.1 199 mdrdkrwdrveigmrgiitgegeastdpvktieeryakgendeflkpiivggkenrvhdddtlfffnyrsdrvreitqllggydrspipdfpypkn 294
                    ************************************************************************************************ PP

                    .......................................HHHHTT-----EEEEEEEE-S---SSHHHHHT--EEEE--SHHSTT--HHHHHHHHH CS
                    .......................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Metalloenzyme  68 .......................................lrisetvkfahvtffwnggrsgyfnpleereeipsdtvitfdlqpemkavevaekal 124
                                                            +i+et+k+ahvtff+ngg +++f++ eer  ips+ v+t+dlqp+m+a +v e+++
     EEA20720.1 295 iqittmtqyksdypfpvafppqhmgnvlaewlgkqnisqSHIAETEKYAHVTFFFNGGIEKQFPG-EERDMIPSPRVATYDLQPKMSAWAVGERVA 389
                    ***************************************99************************.****************************** PP

                    HHH.CC.-SEEEEEE-HHHHHHHTT-HHHHHHHHHHHHHHHHHHHTTS-TTTEEEEEE-SSB--TTTSS........-----EEEEEESTT----S CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Metalloenzyme 125 dailsgkfdlvvvniknaDmvGHtgdleatiaaieaaDeavkeildaieqvdgilvvtADHgnaedmvkrdkqplTsHtlepVPilivgkglapdk 220
                    + i ++kf lv+ n++ +DmvGHtg +ea+i+++ + D+a+++i +a+++++ il++tADHgnae+m +++++p TsHtl++VP+++++    +  
     EEA20720.1 390 ERIAEEKFGLVMNNFAPPDMVGHTGVYEAAIQGVAETDRAIGHIYEACKKHGYILFITADHGNAEEMLNEERKPKTSHTLNKVPFVMANAP--E-- 481
                    **************************************************************************************99884..2.. PP

                    --SSHHHHTT-TTEEEEGGGHHHHHHH CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Metalloenzyme 221 vkegakfrekggLanvaatllnllgle 247
                      +    +e g L++va+t+l+ +g+e
     EEA20720.1 482 --GWSLKKEGGVLGDVAPTILEAMGIE 506
                    ..122234699*************998 PP

>> Phosphodiest  Type I phosphodiesterase / nucleotide pyrophosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.0   5.3e-09   1.6e-05     168     237 ..     390     455 ..     298     485 .. 0.83

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 5.3e-09
                   HCT..SSESEEEEEECCCHHHHHHH-TTSHHHHHHHHHHHHHHHHHHHHHHHTTGTTTEEEEEEES---EEE CS
  Phosphodiest 168 kel..ekpdlllvyleetDtvgHkfGpdspevedalrrvDkaigdLlealderglsaetniilvSDHGmadv 237
                   ++   ek  l++ ++  +D vgH  G ++ +  + +++ D+aig+++ea +++     + +++++DHG a+ 
    EEA20720.1 390 ERIaeEKFGLVMNNFAPPDMVGH-TGVYE-AAIQGVAETDRAIGHIYEACKKH----GYILFITADHGNAEE 455
                   22234999***************.66655.66899******************....999********8765 PP

>> Sulfatase  Sulfatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.0   4.1e-08   0.00012     208     309 .]     364     505 ..     295     505 .. 0.72

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 4.1e-08
                 H.................................................HHHHHHHHHHHHHHHHHHHHHHHHHHTTTGGGEEEEEEESSSSCCCGHH CS
   Sulfatase 208 r.................................................qlleaylnsveyvDdligrvlaaLeenglldntlvvftSDhgasleesn 257
                                                                    ++ea  + v+++D +ig +++a     ++   ++++t+Dhg +  e  
  EEA20720.1 364 MipsprvatydlqpkmsawavgervaeriaeekfglvmnnfappdmvghtGVYEAAIQGVAETDRAIGHIYEAC----KKHGYILFITADHGNAE-E-- 455
                 0555555555555555556666666666666666666666666777766688999999****************....666789*********54.4.. PP

                 TTSSSCTTCSSSHHHHBEEEEEEETTTSHCEEECSEEEGGGHHHHHHHHTTE CS
   Sulfatase 258 gplrggkganayeggtrvPllvwwpgekaprvseelvshiDlfptildlagi 309
                   l  + + ++++   +vP++++   e  +  ++e   + D++ptil+++gi
  EEA20720.1 456 -MLNEERKPKTSHTLNKVPFVMANAPEGWS-LKKEGGVLGDVAPTILEAMGI 505
                 .355555558899999******98887777.666667778**********97 PP

>> Alk_phosphatase  Alkaline phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0      0.21   6.2e+02       2      27 ..     153     178 ..     152     198 .. 0.85
   2 ?   10.3   0.0   7.8e-05      0.23     263     322 ..     408     466 ..     404     480 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.21
                      SEEEEEEETT-SHHHHHHHHHHHCHC CS
  Alk_phosphatase   2 knvilligDGmgvstvtaaRslkeqa 27 
                      k +i + gDG  +   +aaR+++e  
       EEA20720.1 153 KVIIHFFGDGRDTDPKSAARYMQELL 178
                      67899***************998754 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 7.8e-05
                      HHHHHTTTHHHHHHHHHHHHHHHHHHHHHCHHCTTEEEEEEESSEESEEEESTTSTT..T CS
  Alk_phosphatase 263 DhaaHendavgalsEvvefdeAvkaalefakkeketlvvvTaDHshvfsfggyttrgesv 322
                      D  +H +    a++ v e d+A+ +  e+ kk+   ++  TaDH  + ++   + ++++ 
       EEA20720.1 408 DMVGHTGVYEAAIQGVAETDRAIGHIYEACKKHGY-ILFITADHGNAEEMLNEERKPKTS 466
                      6778999999*********************6655.5567******99988877776554 PP

>> AP_endonuc_2  Xylose isomerase-like TIM barrel
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0     5e-05      0.15      33     109 ..     142     208 ..     103     217 .. 0.63

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 5e-05
                   HHHHHHHTTSEEEEEEECCCHSTCTHCHTTCSHHHHHHHHHHHHHHHHHHTBSEEEEEBCCGBCTTTSGHHHHHHHH CS
  AP_endonuc_2  33 lrkaldelglriaslslftrfgypdederearreesvdalkraielaaaLGapllvlhpGtagagpkgseeeawerl 109
                   l + +++ g+  + +++f++  + d    +++     +++++ ++ +++LG+  + + +G   +++  +++ +w+r+
    EEA20720.1 142 LLQVAKDMGVPKVIIHFFGDGRDTDP---KSA----ARYMQELLDKTKELGIGEVGTVVG---RYYVMDRDKRWDRV 208
                   44455555555555555555555443...233....556666666666666666666666...55666666666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (520 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       412  (0.0229795); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.59u 0.26s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 3468.60
//
Query:       EEA20721.1  [L=127]
Description: prefoldin subunit 6, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.4e-21   74.5  17.3    7.3e-21   74.1  17.3    1.2  1  Prefoldin_2     Prefoldin subunit
    0.00018   21.5   5.9    0.00028   20.9   5.9    1.3  1  Prefoldin_3     Prefoldin subunit
    0.00037   20.7  12.0      0.084   13.1   5.6    2.1  2  Spc24           Spc24 subunit of Ndc80
  ------ inclusion threshold ------
      0.014   14.3  17.0      0.019   13.9  17.0    1.1  1  Spc7            Spc7 kinetochore protein
      0.016   15.4   1.6      0.016   15.4   1.6    2.0  2  XhlA            Haemolysin XhlA
       0.02   12.8  12.7      0.026   12.3  12.7    1.1  1  Myosin_tail_1   Myosin tail
      0.081   13.2  10.2       0.82   10.0   3.3    2.2  2  Rx_N            Rx N-terminal domain
       0.14   12.1  18.1        5.7    6.9  18.1    2.6  1  Prefoldin       Prefoldin subunit
       0.16   12.0  15.5       0.83    9.7   5.4    2.1  2  CENP-F_leu_zip  Leucine-rich repeats of kinetochore protein C
       0.21   11.4  23.2       0.33   10.8   2.8    3.2  3  DivIC           Septum formation initiator
       0.25    9.5  14.4       0.17   10.1   3.7    2.0  2  EzrA            Septation ring formation regulator, EzrA
       0.33   11.3   8.8        3.9    7.9   0.1    2.9  2  HalX            HalX domain
       0.35   11.5  11.8        2.4    8.8   1.3    2.1  2  YabA            Initiation control protein YabA
       0.57   10.4   6.7       0.92    9.7   6.7    1.4  1  PHM7_cyt        Cytosolic domain of 10TM putative phosphate t
       0.65    8.8  15.7         19    4.0  14.0    2.1  1  CALCOCO1        Calcium binding and coiled-coil domain (CALCO
       0.71   10.3  13.8       0.22   12.0   1.2    2.3  2  CENP-H          Centromere protein H (CENP-H)
       0.96   10.4   6.2        3.9    8.4   6.1    2.0  1  ERp29           Endoplasmic reticulum protein ERp29, C-termin
        1.1    9.5  17.3        2.8    8.2   3.5    2.1  2  TMF_TATA_bd     TATA element modulatory factor 1 TATA binding
        1.1    8.4  17.6         15    4.6  17.7    2.0  1  Taxilin         Myosin-like coiled-coil protein
        1.1    9.6  19.2        1.4    9.3   1.9    3.9  3  Csm1_N          Csm1 N-terminal domain
        1.2    9.5  17.0        4.6    7.7   4.3    2.4  2  DUF4200         Domain of unknown function (DUF4200)
        1.3    9.5  13.3       0.89   10.1   2.4    2.2  2  NPV_P10         Nucleopolyhedrovirus P10 protein
        1.4    9.0  11.9        1.9    8.6  11.9    1.2  1  End3            Actin cytoskeleton-regulatory complex protein
        1.8    8.0  15.4      0.048   13.1   1.2    2.1  2  DUF4349         Domain of unknown function (DUF4349)
          2    8.8  20.6        1.6    9.0   1.9    3.3  3  ABC_tran_CTD    ABC transporter C-terminal domain
        2.4    8.2   5.6          1    9.4   0.8    2.1  2  Bcr-Abl_Oligo   Bcr-Abl oncoprotein oligomerisation domain
        2.6    8.5  12.5        5.1    7.6   1.9    3.2  3  FlaC_arch       Flagella accessory protein C (FlaC)
        2.6    7.7  13.1        5.4    6.6   3.7    2.2  2  GrpE            GrpE
        2.7    7.3  14.3        6.6    6.0  14.3    1.5  1  DUF4407         Domain of unknown function (DUF4407)
        3.2    7.9  17.5         66    3.7  17.5    2.0  1  Fib_alpha       Fibrinogen alpha/beta chain family
        3.4    8.2  22.0          4    8.0   5.1    2.1  2  APG6_N          Apg6 coiled-coil region
        4.1    7.4  14.2       0.91    9.5   7.0    2.1  2  Rootletin       Ciliary rootlet component, centrosome cohesio
        4.3    7.4   7.9         46    4.0   7.9    2.0  1  MCU             Mitochondrial calcium uniporter
        4.7    7.3  17.0       0.45   10.6   2.3    2.4  2  BRE1            BRE1 E3 ubiquitin ligase
        5.2    7.4  27.3        4.4    7.6  13.3    2.1  2  OmpH            Outer membrane protein (OmpH-like)
        7.9    6.2  19.9    2.1e+02    1.6  19.9    2.0  1  ERM             Ezrin/radixin/moesin family
        8.2    6.5  12.7        5.1    7.2   3.2    2.1  2  DUF1664         Protein of unknown function (DUF1664)
        9.4    5.5   8.0        1.9    7.8   0.4    2.0  2  CorA            CorA-like Mg2+ transporter protein


Domain annotation for each model (and alignments):
>> Prefoldin_2  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.1  17.3   1.6e-23   7.3e-21       1     105 [.       9     113 ..       9     117 .. 0.97

  Alignments for each domain:
  == domain 1  score: 74.1 bits;  conditional E-value: 1.6e-23
                  HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS-TT--EEEEETTEEEEE-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Prefoldin_2   1 qelinkfqqlqqqlqqlaqqikqletqlkelelvleelelldedtkvyklvGdvlvkqdkeevkeeLeerketlekeiktlekqleklekeleelkee 98 
                  q l +++q+lq++l+ +   +++le q +e++ v++e+ +ld+d ++yklvG+vl+kq+k e+   ++ r+e++ekeik++e q+++++++ ++ ++e
   EEA20721.1   9 QTLSEEYQNLQAELETIILARQKLESQQQENQAVQQEFASLDDDSNIYKLVGPVLLKQEKSEAVMAVDGRLEFIEKEIKRIEGQIQEINNKSDKKRTE 106
                  66789********************************************************************************************* PP

                  HHCCTS- CS
  Prefoldin_2  99 lqkklqq 105
                  + +++ q
   EEA20721.1 107 IIQLQSQ 113
                  *998865 PP

>> Prefoldin_3  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   5.9   5.9e-07   0.00028       4      97 ..       5      99 ..       2     101 .. 0.87

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 5.9e-07
  Prefoldin_3  4 lyklreweaeydglkeeisalke...eddateedllriardfegslvtekEveeilGekqgvtrskqQvvdlisrRiDYVkqniktlekrleaaenk 97
                  + l++ ++ey++l++e++++     + ++++++   ++++f + l ++  + +++G     +++k   v +++ R+ ++++ ik +e +++  +nk
   EEA20721.1  5 QKALQTLSEEYQNLQAELETIILarqKLESQQQENQAVQQEFAS-LDDDSNIYKLVGPVLL-KQEKSEAVMAVDGRLEFIEKEIKRIEGQIQEINNK 99
                 567899999999999999998555557789999999******75.77999*******9877.899999999********************999988 PP

>> Spc24  Spc24 subunit of Ndc80
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.1   5.6   0.00018     0.084       9      57 ..       4      58 ..       2      59 .. 0.85
   2 !   11.7   0.4   0.00051      0.24       9      43 ..      82     116 ..      75     126 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 0.00018
       Spc24  9 iakelsdleselesleselaelkeeleeleeeseekeser......vedetllkl 57
                ++k+l+ l +e ++l++el+      ++le++++e+++ +       +d++++kl
  EEA20721.1  4 AQKALQTLSEEYQNLQAELETIILARQKLESQQQENQAVQqefaslDDDSNIYKL 58
                6899******************************94444467788566****998 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 0.00051
       Spc24   9 iakelsdleselesleselaelkeeleeleeesee 43 
                 i ke++ +e ++++++++ +++++e+ +l+++ ++
  EEA20721.1  82 IEKEIKRIEGQIQEINNKSDKKRTEIIQLQSQVQQ 116
                 789***************************99888 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9  17.0   3.9e-05     0.019     142     254 ..       2     118 ..       1     122 [. 0.88

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 3.9e-05
        Spc7 142 egleenlegleedkelLekqeeeldellpeleeeka...eleeeleklqeaaeelesidkeeLeelree.laelkaeieekkkelaelqeqleeleeki 236
                 e++++ l++l e++++L+++ e +  + ++le++++   ++++e+++l + ++  + + +  L++ ++e + +++  +e  +ke+++ + q++e+++k 
  EEA20721.1   2 EQAQKALQTLSEEYQNLQAELETIILARQKLESQQQenqAVQQEFASLDDDSNIYKLVGPVLLKQEKSEaVMAVDGRLEFIEKEIKRIEGQIQEINNKS 100
                 7899******************998888888766654448**********999999999****998865378999************************ PP

        Spc7 237 eelkeqkseleeeiaeae 254
                 ++ ++++ +l++++++++
  EEA20721.1 101 DKKRTEIIQLQSQVQQQQ 118
                 *************99976 PP

>> XhlA  Haemolysin XhlA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.5         3   1.4e+03      12      24 ..      14      26 ..       2      52 .. 0.51
   2 ?   15.4   1.6   3.4e-05     0.016       5      41 ..      78     114 ..      74     116 .. 0.92

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 3
        XhlA 12 kldnleervdkle 24
                +  nl+ +++++ 
  EEA20721.1 14 EYQNLQAELETII 26
                4444444333333 PP

  == domain 2  score: 15.4 bits;  conditional E-value: 3.4e-05
        XhlA   5 rlerietkldnleervdkleekaaeaeekiknleedl 41 
                 rle ie++++ +e +++++++k+++ +++i++l+ ++
  EEA20721.1  78 RLEFIEKEIKRIEGQIQEINNKSDKKRTEIIQLQSQV 114
                 8999*****************************9876 PP

>> Myosin_tail_1  Myosin tail
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3  12.7   5.6e-05     0.026     375     474 ..       4     118 ..       1     122 [. 0.78

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 5.6e-05
  Myosin_tail_1 375 lekakqaLesenkelqaelkslqqakqdseqkrkkleaqlqelqvklsese........rqreelae.......kvsklqaelesvsslleeaegk 455
                     +ka q+L +e ++lqael+++  a+q  e++++  +a  qe+ +  ++s+          ++e++e       +++ +++e+  ++++++e ++k
     EEA20721.1   4 AQKALQTLSEEYQNLQAELETIILARQKLESQQQENQAVQQEFASLDDDSNiyklvgpvLLKQEKSEavmavdgRLEFIEKEIKRIEGQIQEINNK 99 
                    57999**********************9999999999999999998888873322222223456555111222256667889999999999999** PP

  Myosin_tail_1 456 siklskdvsslesqlqDtq 474
                    s k   ++ +l+sq+q  q
     EEA20721.1 100 SDKKRTEIIQLQSQVQQQQ 118
                    ****************988 PP

>> Rx_N  Rx N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   3.3    0.0017      0.82      15      56 ..       3      44 ..       1      51 [. 0.88
   2 ?    7.7   0.6    0.0088       4.1      14      51 ..      65     103 ..      57     120 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.0017
        Rx_N 15 eeakllkgvkeeleklkdeLesiqavLedaeerqikdeavke 56
                +  k l+ + ee ++l+ eLe+i    ++ e +q++++av++
  EEA20721.1  3 QAQKALQTLSEEYQNLQAELETIILARQKLESQQQENQAVQQ 44
                55588999*******************************986 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0088
        Rx_N  14 aeea.kllkgvkeeleklkdeLesiqavLedaeerqikd 51 
                 ++e  + ++ v++ le++++e ++i++ +++  ++ +k 
  EEA20721.1  65 KQEKsEAVMAVDGRLEFIEKEIKRIEGQIQEINNKSDKK 103
                 444459999********************9999987754 PP

>> Prefoldin  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9  18.1     0.012       5.7       9     118 ..       2     118 ..       1     120 [. 0.85

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.012
                 HHHHHHHHHHHHHHHHHHHHHHHHTT.-TT-EEEEEEETTEEEEEE--STTEEEEEEETTEEEEEEHHHHH.......HHHHHHHHHHHHHHHHHHHHH CS
   Prefoldin   9 qaelaqlkeaieelektletlktlkkedegkevlvplgaglyvkaevkdtdkvlvdlGagyyveksleeAi.......ellkkkleelekqlekleeel 100
                 ++ +++l++  ee++++ + l+t++ + +  e + + ++ ++ +    d+d+ + +l   + ++ ++ eA+       e+++k+++ +e q+++++++ 
  EEA20721.1   2 EQAQKALQTLSEEYQNLQAELETIILARQKLESQQQENQAVQQEFASLDDDSNIYKLVGPVLLKQEKSEAVmavdgrlEFIEKEIKRIEGQIQEINNKS 100
                 567889999999999999999999999999999999999999999988888888888888999999999965555555899999999999999999999 PP

                 HHHHHHHHHHHHHHHHHH CS
   Prefoldin 101 eklkdqittleanlaqly 118
                 +k++++i +l+ +++q +
  EEA20721.1 101 DKKRTEIIQLQSQVQQQQ 118
                 999999999999999976 PP

>> CENP-F_leu_zip  Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   5.4    0.0018      0.83      54      96 ..       1      43 [.       1      55 [. 0.85
   2 ?    8.2   2.4    0.0049       2.3      12      63 ..      64     116 ..      61     120 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0018
  CENP-F_leu_zip 54 vetlkeeieelaeelreleldLvalrsekeeLekelqkkqerv 96
                    +e+ ++ +++l+ee ++l+++L+++   +++Le + q++q   
      EEA20721.1  1 MEQAQKALQTLSEEYQNLQAELETIILARQKLESQQQENQAVQ 43
                    57889999************************99999988654 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.0049
  CENP-F_leu_zip  12 LKeserkad.sLkdkvenLerelemseenqekvileaEtskaevetlkeeiee 63 
                     LK+ +++a   + ++ e +e+e++ +e + +++    ++++ e+ +l++++++
      EEA20721.1  64 LKQEKSEAVmAVDGRLEFIEKEIKRIEGQIQEINNKSDKKRTEIIQLQSQVQQ 116
                     55555555314667888888888888888888888888888888888888775 PP

>> DivIC  Septum formation initiator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   2.3      0.08        38      27      48 ..       2      23 ..       1      25 [. 0.85
   2 ?   10.8   2.8   0.00069      0.33      29      59 ..      28      57 ..      23      59 .. 0.79
   3 ?    8.3   3.3    0.0041       1.9      19      49 ..      86     116 ..      79     126 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.08
                HHHHHHHHHHHHHHHHHHHHHC CS
       DivIC 27 aalqaelaklkaeneeLeaevk 48
                ++ q+ l++l++e ++L+ae++
  EEA20721.1  2 EQAQKALQTLSEEYQNLQAELE 23
                6889999999999999999976 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00069
                HHHHHHHHHHHHHHHHHHHCC-XXXXXXXXX CS
       DivIC 29 lqaelaklkaeneeLeaevkdLksdedyiee 59
                  ++l+++++en++ ++e + L +d++ i +
  EEA20721.1 28 ARQKLESQQQENQAVQQEFASL-DDDSNIYK 57
                5789999999999999999999.78877765 PP

  == domain 3  score: 8.3 bits;  conditional E-value: 0.0041
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC CS
       DivIC  19 ykqlkqeiaalqaelaklkaeneeLeaevkd 49 
                 +k+++ +i++++++ +k++ e+ +L+++v++
  EEA20721.1  86 IKRIEGQIQEINNKSDKKRTEIIQLQSQVQQ 116
                 6788999999999999999999999999986 PP

>> EzrA  Septation ring formation regulator, EzrA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   3.0    0.0086       4.1     274     312 ..       2      40 ..       1      59 [. 0.67
   2 ?   10.1   3.7   0.00035      0.17     101     147 ..      70     116 ..      63     120 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0086
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTSSSSS CS
        EzrA 274 edveeelktieeeidsLyddlekEveAkkeveknlkelk 312
                 e+++++l+t++ee+++L   le+ + A+++ e++++e +
  EEA20721.1   2 EQAQKALQTLSEEYQNLQAELETIILARQKLESQQQENQ 40 
                 566677777777777777777777777777776666544 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00035
                 HHHHHHHHHHHHHHHHHHHHHHHHTHHHHTTTTTHHHHHHHHHHHHH CS
        EzrA 101 kklaeleeeldeveekikkileelkelteseeknreeieklkekYre 147
                 +++ +++ +l+ +e++ik+i  +++e+ ++  k+r+ei +l+++ ++
  EEA20721.1  70 EAVMAVDGRLEFIEKEIKRIEGQIQEINNKSDKKRTEIIQLQSQVQQ 116
                 566778889999*****************************998765 PP

>> HalX  HalX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   4.9      0.14        66      34      47 ..      12      25 ..       3      53 .. 0.72
   2 ?    7.9   0.1    0.0083       3.9      21      60 ..      63     102 ..      62     115 .. 0.89

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.14
        HalX 34 seeYqeLearleel 47
                seeYq L+a+le++
  EEA20721.1 12 SEEYQNLQAELETI 25
                89999999999974 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0083
        HalX  21 vLeaekseaeLadseeYqeLearleelraqldetldeldd 60 
                 +L+ eksea +a + + + +e ++ +++ q+ e+ +  d 
  EEA20721.1  63 LLKQEKSEAVMAVDGRLEFIEKEIKRIEGQIQEINNKSDK 102
                 69******************************99887554 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   3.4    0.0085         4      26      66 ..       3      45 ..       1      58 [. 0.47
   2 ?    8.8   1.3    0.0052       2.4       3      57 ..      65     119 ..      63     126 .. 0.87

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0085
                HHHHHHHHHHHHHHHHHHHHHHH...HHHHXXXXXXXXXXXXXX CS
        YabA 26 elkeelaelleenaeLelenekl...rerleeeekkekekkkel 66
                + +++l++l ee ++L++e e++   r++le++++++++ ++  
  EEA20721.1  3 QAQKALQTLSEEYQNLQAELETIilaRQKLESQQQENQAVQQ-E 45
                555666666666666666666543334444333222222222.2 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0052
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHXXXXX CS
        YabA   3 kkelfdkleeleeqleelleeleelkeelaelleenaeLeleneklrerleeeek 57 
                 k+e  +++++++ +le + +e+++++ +++e+ ++ ++ ++e  +l++++++++ 
  EEA20721.1  65 KQEKSEAVMAVDGRLEFIEKEIKRIEGQIQEINNKSDKKRTEIIQLQSQVQQQQP 119
                 5666788999999**********************************99976654 PP

>> PHM7_cyt  Cytosolic domain of 10TM putative phosphate transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   6.7    0.0019      0.92      42     134 ..       6     117 ..       1     127 [] 0.73

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0019
    PHM7_cyt  42 kkldklveerekavrkleaalskykkngkklpkkr........................pthklgflglkligkkvda.idyyrekleeldeeieeere 115
                 k l+ l ee ++++ +le+++  ++k +++++ ++                        ++ k            vd  ++++++++++++ +i+e ++
  EEA20721.1   6 KALQTLSEEYQNLQAELETIILARQKLESQQQENQavqqefasldddsniyklvgpvllKQEKSEAV------MAVDGrLEFIEKEIKRIEGQIQEINN 98 
                 67999**************99888887776665668999******9998777666654422222221......13554589999999999999999999 PP

    PHM7_cyt 116 kvkkkplgaaFvtfesers 134
                 k +kk+++++  + + +++
  EEA20721.1  99 KSDKKRTEIIQLQSQVQQQ 117
                 9999998887765554433 PP

>> CALCOCO1  Calcium binding and coiled-coil domain (CALCOCO1) like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0  14.0      0.04        19     165     219 ..      64     118 ..       8     125 .. 0.79

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.04
    CALCOCO1 165 qrkeeeaerkqlqakleqseeelrslskelqelrnslaerdtqvlqLqdtittlt 219
                 +++e+ +   +++ +le  e+e++++  ++qe+ n+ +++ t+++qLq+++++ +
  EEA20721.1  64 LKQEKSEAVMAVDGRLEFIEKEIKRIEGQIQEINNKSDKKRTEIIQLQSQVQQQQ 118
                 345555556789999***********************************98865 PP

>> CENP-H  Centromere protein H (CENP-H)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   5.4      0.18        86       8      41 ..       8      44 ..       1      59 [. 0.49
   2 ?   12.0   1.2   0.00046      0.22       9      62 ..      66     119 ..      61     127 .] 0.89

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.18
      CENP-H  8 rdelssellklsqelrel...qeeltevekenlrlkr 41
                 ++ls+e+++l++el+++   +++l++ ++en ++++
  EEA20721.1  8 LQTLSEEYQNLQAELETIilaRQKLESQQQENQAVQQ 44
                3444444444444444422224444444444444444 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 0.00046
      CENP-H   9 delssellklsqelrelqeeltevekenlrlkrknrelaaellelakekeseke 62 
                 +e s+++++    l+ +++e+ ++e ++ ++++k+ ++ +e+ +l+++ +++++
  EEA20721.1  66 QEKSEAVMAVDGRLEFIEKEIKRIEGQIQEINNKSDKKRTEIIQLQSQVQQQQP 119
                 57799999**********************************999999999884 PP

>> ERp29  Endoplasmic reticulum protein ERp29, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   6.1    0.0083       3.9      20      86 ..      31     107 ..       1     114 [. 0.67

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0083
       ERp29  20 ereelleeakkaaeklksekekkaaeyYvkvmekiaekge...........eyvekElkRLekllk.kgklaaekkdel 86 
                 + e+  +e ++++++ +  + ++  ++Y  v   ++++++           e++ekE+kR+e+ ++  ++ +++k++e+
  EEA20721.1  31 KLESQQQENQAVQQEFA--SLDDDSNIYKLVGPVLLKQEKseavmavdgrlEFIEKEIKRIEGQIQeINNKSDKKRTEI 107
                 33333333333333333..66677788888777777777777899999999***********99974456666666665 PP

>> TMF_TATA_bd  TATA element modulatory factor 1 TATA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   8.0     0.034        16      29      78 ..       2      51 ..       1      73 [. 0.85
   2 ?    8.2   3.5     0.006       2.8      12      60 ..      70     118 ..      62     123 .. 0.84

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.034
  TMF_TATA_bd 29 aslkeelerleaerdeareeivklmkeneelkelkkeleelekeleelqe 78
                 +++++ l++l++e +++++e+ +++   ++l+++++e++ +++e+++l++
   EEA20721.1  2 EQAQKALQTLSEEYQNLQAELETIILARQKLESQQQENQAVQQEFASLDD 51
                 67899999999999999999999999999999999999999999998875 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.006
  TMF_TATA_bd  12 qlverlsseirrlEgElaslkeelerleaerdeareeivklmkeneelk 60 
                  + v     ++   E E++ ++ ++++++++ d+ r ei++l +++++++
   EEA20721.1  70 EAVMAVDGRLEFIEKEIKRIEGQIQEINNKSDKKRTEIIQLQSQVQQQQ 118
                  55666667788899***************************99998875 PP

>> Taxilin  Myosin-like coiled-coil protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6  17.7     0.032        15      42     141 ..       2     115 ..       1     118 [. 0.75

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.032
     Taxilin  42 kklkkkleqlqkekeqlqaelskaalaksKLekLcRelqkqnkklk...ees........kqrareeeekrkelaekf...qakLkdiqaqieeksern 126
                  +++k l++l +e ++lqael+  +la++KLe+  +e q  +++     ++s        + + +e+ e+  +++ ++   ++++k i+ qi+e ++++
  EEA20721.1   2 EQAQKALQTLSEEYQNLQAELETIILARQKLESQQQENQAVQQEFAsldDDSniyklvgpVLLKQEKSEAVMAVDGRLefiEKEIKRIEGQIQEINNKS 100
                 57899****************************9887665555444333554222222224556777777777777752236999************** PP

     Taxilin 127 eklreenaelteKlk 141
                 +k r e  +l++  +
  EEA20721.1 101 DKKRTEIIQLQSQVQ 115
                 **9999999998765 PP

>> Csm1_N  Csm1 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.3       0.6   2.8e+02      34      52 ..       6      24 ..       1      26 [. 0.66
   2 ?    9.3   1.9     0.003       1.4      33      57 ..      29      53 ..      22      57 .. 0.87
   3 ?    5.2   4.4     0.058        27      36      62 ..      79     105 ..      68     124 .. 0.70

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.6
      Csm1_N 34 qkletkdqeiesLkeqlae 52
                ++l+t ++e ++L+++l++
  EEA20721.1  6 KALQTLSEEYQNLQAELET 24
                4566777777777777765 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.003
      Csm1_N 33 sqkletkdqeiesLkeqlaeleekv 57
                +qkle+++qe ++++++ a+l+ ++
  EEA20721.1 29 RQKLESQQQENQAVQQEFASLDDDS 53
                79*******************9876 PP

  == domain 3  score: 5.2 bits;  conditional E-value: 0.058
      Csm1_N  36 letkdqeiesLkeqlaeleekvkelee 62 
                 le  ++ei++++ q++e+++k+++  +
  EEA20721.1  79 LEFIEKEIKRIEGQIQEINNKSDKKRT 105
                 555567777777777777777666544 PP

>> DUF4200  Domain of unknown function (DUF4200)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   4.8     0.011         5      69     107 ..       2      40 ..       1      56 [. 0.73
   2 ?    7.7   4.3    0.0098       4.6      55      90 ..      80     115 ..      64     121 .. 0.57

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.011
     DUF4200  69 eeerklkkekeaeikklkaeietlkseiekleekleeyk 107
                 e+ +k+ +   +e ++l+ae+et+   ++kle + +e +
  EEA20721.1   2 EQAQKALQTLSEEYQNLQAELETIILARQKLESQQQENQ 40 
                 566777777777777777888877777777777777765 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0098
     DUF4200  55 kendakraralkkaeeerklkkekeaeikklkaeie 90 
                 + ++++ +r + +++e +++ ++k  ei +l+++++
  EEA20721.1  80 EFIEKEIKRIEGQIQEINNKSDKKRTEIIQLQSQVQ 115
                 555555555555555555555555555555555555 PP

>> NPV_P10  Nucleopolyhedrovirus P10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   3.4     0.069        32      20      59 ..       8      47 ..       2      58 .. 0.83
   2 ?   10.1   2.4    0.0019      0.89      11      60 ..      70     116 ..      62     120 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.069
     NPV_P10 20 VdalqqqvddvqenlpdvtelnekLdaqsaqLaeletkve 59
                ++ l+++ +++q++l+++    +kL++q+++ ++++++  
  EEA20721.1  8 LQTLSEEYQNLQAELETIILARQKLESQQQENQAVQQEFA 47
                567888999*********999********99999988654 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.0019
     NPV_P10  11 adikavddkVdalqqqvddvqenlpdvtelnekLdaqsaqLaeletkven 60 
                 +++ avd +++ +++++++++ ++++   +n+k d+  +++ +l+++v++
  EEA20721.1  70 EAVMAVDGRLEFIEKEIKRIEGQIQE---INNKSDKKRTEIIQLQSQVQQ 116
                 6899*****************97666...99***************9986 PP

>> End3  Actin cytoskeleton-regulatory complex protein END3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6  11.9    0.0039       1.9     103     199 .]       5     111 ..       1     111 [. 0.72

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0039
        End3 103 kreLaeLeeklekveeeaekr...kekereessksalvkreleqLLk....YKeeq...lreleegegkskeknlksvkedietveeqVegLesylssr 191
                 ++ L+ L e+ +++++e e+    ++k ++++++++ v++e+  L +    YK      l++++++   +++  l+ ++++i+ +e q+++ ++  +++
  EEA20721.1   5 QKALQTLSEEYQNLQAELETIilaRQKLESQQQENQAVQQEFASLDDdsniYKLVGpvlLKQEKSEAVMAVDGRLEFIEKEIKRIEGQIQEINNKSDKK 103
                 5666666666666666666544433566677889999******9976667799754221444444445555588************************* PP

        End3 192 keeLeqLk 199
                 ++e+ qL+
  EEA20721.1 104 RTEIIQLQ 111
                 **999986 PP

>> DUF4349  Domain of unknown function (DUF4349)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   7.0      0.86     4e+02      96     145 ..       6      52 ..       1      58 [. 0.75
   2 ?   13.1   1.2    0.0001     0.048     110     162 ..      64     117 ..      61     126 .. 0.77

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.86
     DUF4349  96 kaleasedrllallekaksvedlleiereLsevqaeieslegqlryLdnq 145
                 kal+++ + +++l   ++++e ++ + ++L++ q+e  + ++++++Ld+ 
  EEA20721.1   6 KALQTLSEEYQNL---QAELETIILARQKLESQQQENQAVQQEFASLDDD 52 
                 3333333333333...6899***************************986 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 0.0001
     DUF4349 110 ekaksvedlleiereLsevqaeieslegqlryLdnqvaystvtv.tlrepeaet 162
                  k+++ e ++++  +L+ +++ei ++egq+++++n+ +  + ++ +l+++++++
  EEA20721.1  64 LKQEKSEAVMAVDGRLEFIEKEIKRIEGQIQEINNKSDKKRTEIiQLQSQVQQQ 117
                 578999*****************************9998766641444433333 PP

>> ABC_tran_CTD  ABC transporter C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   1.9    0.0034       1.6      40      59 ..       5      24 ..       1      27 [. 0.85
   2 ?    1.9   0.6      0.55   2.6e+02      16      52 ..      31      48 ..      25      58 .. 0.51
   3 ?    8.4   3.8    0.0052       2.5       9      33 ..      78     102 ..      66     122 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.0034
  ABC_tran_CTD 40 peklaelsaeleeleaeLee 59
                  +++l+ ls+e+++l+aeLe+
    EEA20721.1  5 QKALQTLSEEYQNLQAELET 24
                  3779**************98 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.55
  ABC_tran_CTD 16 eIeaLEeeiaeleaeladpelysdpeklaelsaelee 52
                  ++e+ ++e +++++e+a                    
    EEA20721.1 31 KLESQQQENQAVQQEFA-------------------S 48
                  33333333334444433...................3 PP

  == domain 3  score: 8.4 bits;  conditional E-value: 0.0052
  ABC_tran_CTD   9 eleeleaeIeaLEeeiaeleaelad 33 
                   +le +e+eI ++E +i+e++++  +
    EEA20721.1  78 RLEFIEKEIKRIEGQIQEINNKSDK 102
                   588899***********99997654 PP

>> Bcr-Abl_Oligo  Bcr-Abl oncoprotein oligomerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.3      0.78   3.7e+02      20      41 ..      19      40 ..       2      51 .. 0.57
   2 ?    9.4   0.8    0.0022         1      26      65 ..      79     118 ..      66     121 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.78
  Bcr-Abl_Oligo 20 kmeLdsvedieqeLerCkaslr 41
                   + eL+++    q Le  +++ +
     EEA20721.1 19 QAELETIILARQKLESQQQENQ 40
                   2344444444444444444444 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.0022
  Bcr-Abl_Oligo  26 vedieqeLerCkaslrrLekelneekfkviyLqtllaker 65 
                    +e ie+e++r   ++++++++  + +  +i Lq+ + +++
     EEA20721.1  79 LEFIEKEIKRIEGQIQEINNKSDKKRTEIIQLQSQVQQQQ 118
                    6779*****************************9988765 PP

>> FlaC_arch  Flagella accessory protein C (FlaC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.2       0.2        93      13      32 ..       5      24 ..       1      28 [. 0.48
   2 ?    4.4   1.5       0.1        49       7      35 ..      20      51 ..      16      60 .. 0.74
   3 ?    7.6   1.9     0.011       5.1       1      38 [.      78     115 ..      71     117 .. 0.80

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.2
   FlaC_arch 13 steletvkkeneelsksvee 32
                +  l+t+ +e ++l+ ++e+
  EEA20721.1  5 QKALQTLSEEYQNLQAELET 24
                34445555555555555544 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.1
   FlaC_arch  7 nklsklst...eletvkkeneelsksveelke 35
                 +l+ +     +le+ ++en+ ++++   l++
  EEA20721.1 20 AELETIILarqKLESQQQENQAVQQEFASLDD 51
                5555554455599************9999987 PP

  == domain 3  score: 7.6 bits;  conditional E-value: 0.011
   FlaC_arch   1 ridelEnklsklsteletvkkeneelsksveelkenVk 38 
                 r++ +E+++++++ +++ + ++ ++ ++++ +l+ +V+
  EEA20721.1  78 RLEFIEKEIKRIEGQIQEINNKSDKKRTEIIQLQSQVQ 115
                 56678888888888888888888888888888887776 PP

>> GrpE  GrpE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   3.7     0.011       5.4      22      64 ..       2      45 ..       1      59 [. 0.74
   2 ?    6.6   2.0     0.012       5.6      12      53 ..      77     118 ..      63     124 .. 0.79

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.011
                TCHHHCTTSCCCCCCTTTTTTT.THHHHHHHHHHHHHHHHHHHH CS
        GrpE 22 eelekevkelkekllrllaefe.nlrkrtekekeeakkfaiekf 64
                e+++k ++ l+e++++l+ae+e  +  r + e ++ ++ a+++ 
  EEA20721.1  2 EQAQKALQTLSEEYQNLQAELEtIILARQKLESQQQENQAVQQE 45
                77888999999999999999994445666666777777776654 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.012
                 HHHCCCCCCTTCHHHCTTSCCCCCCTTTTTTTTHHHHHHHHH CS
        GrpE  12 deeeeleeeleelekevkelkekllrllaefenlrkrtekek 53 
                  ++e  e+e++++e +++e+++k ++++ e+ +l+ ++++++
  EEA20721.1  77 GRLEFIEKEIKRIEGQIQEINNKSDKKRTEIIQLQSQVQQQQ 118
                 556677889999999999999999999999999999888876 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0  14.3     0.014       6.6     127     242 ..       7     123 ..       1     126 [. 0.72

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.014
     DUF4407 127 laaaltaelaeleaqia...alqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaakekkaqldaaqaelaelkakld.atarlaalraelae 221
                   ++l++e+++l+a+++    +++++++++++ +a ++e+++    +  + + +  G     +ek ++  a + +l+ ++++++  + ++++ +++ ++
  EEA20721.1   7 ALQTLSEEYQNLQAELEtiiLARQKLESQQQENQAVQQEFASL---DDDSNIYKLVGPVLLKQEKSEAVMAVDGRLEFIEKEIKrIEGQIQEINNKSDK 102
                 2234677777777777722244555555555555555555533...33677888999999999999999************999888899999999999 PP

     DUF4407 222 leaerakeraasqaaaaaddG 242
                  ++e+++ +++ q+++ a++G
  EEA20721.1 103 KRTEIIQLQSQVQQQQPAAAG 123
                 999999999999999988888 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7  17.5      0.14        66      26     129 ..      11     118 ..       1     123 [. 0.74

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.14
                 CCCCCCCCCHHHCCC...CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  26 llkyekdvkkdlekl...eneleeisnstkeaeelvkeikdslrekqkskkdn.dnvikksskeleeeilrlketidaqesnirvLqnvlesneqkiqk 120
                 l++  ++++ +le++   +++le+ +++++ +++   +++d  +  +   +   ++  ++    ++ + + ++++i++ e +i+++ n  ++++ +i +
  EEA20721.1  11 LSEEYQNLQAELETIilaRQKLESQQQENQAVQQEFASLDDDSNIYKLVGPVLlKQEKSEAVMAVDGRLEFIEKEIKRIEGQIQEINNKSDKKRTEIIQ 109
                 4455555555555554446677777777777777777776666655555554356666667777888999***************************** PP

                 HHHHHHHHH CS
   Fib_alpha 121 Leqdidqke 129
                 L+++++q++
  EEA20721.1 110 LQSQVQQQQ 118
                 *******98 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6  11.5     0.046        22      50      93 ..       2      45 ..       1      58 [. 0.74
   2 ?    8.0   5.1    0.0084         4      14      95 ..      42     118 ..      40     124 .. 0.78

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.046
      APG6_N 50 eeleeeleklekeeeelleeLkelekereeleaelaaleeelea 93
                e++++ l++l++e ++l++eL+ +  +r++le++ ++ ++  ++
  EEA20721.1  2 EQAQKALQTLSEEYQNLQAELETIILARQKLESQQQENQAVQQE 45
                67888888888888888888888888888888887776654444 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0084
      APG6_N  14 ldkqleqaekerdaYeeflkklkkekkeeekqdeeleeleeeleklekeeeelleeLkelekereeleaelaaleeeleale 95 
                 +++++++++++ + Y+     l k++k+     e + + + +le +eke ++ + +++e+ ++ ++ + e+ +l+++ ++ +
  EEA20721.1  42 VQQEFASLDDDSNIYKLVGPVLLKQEKS-----EAVMAVDGRLEFIEKEIKRIEGQIQEINNKSDKKRTEIIQLQSQVQQQQ 118
                 5777777777777777777777777555.....3688888889999999999999999999999999999999999888765 PP

>> Rootletin  Ciliary rootlet component, centrosome cohesion
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   7.0    0.0019      0.91      69     118 ..       4      53 ..       1      58 [. 0.86
   2 ?    2.5   0.6      0.26   1.2e+02      29     137 ..      83     112 ..      63     124 .. 0.50

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.0019
   Rootletin  69 leealakLeeErqrseklaqvnslLreqleearqaneaLtedlqkltkdw 118
                  ++al+ L eE q  +  +++  l r++le ++q+n+a ++++  l +d 
  EEA20721.1   4 AQKALQTLSEEYQNLQAELETIILARQKLESQQQENQAVQQEFASLDDDS 53 
                 46899999999999999899999999999999999999999999998875 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.26
   Rootletin  29 kkrcseleqrllektselektkltlllssareleeeesadleealakLeeErqrseklaqvnslLreqleearqaneaLtedlqkltkdwerlreeleq 127
                  k ++ +e++++e + +++k++ ++++                                                                        
  EEA20721.1  83 EKEIKRIEGQIQEINNKSDKKRTEIIQ------------------------------------------------------------------------ 109
                 444555555555544443333333332........................................................................ PP

   Rootletin 128 kekewreeee 137
                         + 
  EEA20721.1 110 -------LQS 112
                 .......222 PP

>> MCU  Mitochondrial calcium uniporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   7.9     0.098        46      10      92 ..      10     108 ..       2     118 .. 0.64

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.098
                 XXXXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXXX-SS.............SSSSTSSSSSHHHHHHHHHHHHH-SHHHHHHHHTCCCGGGCHHHHG CS
         MCU  10 vlsesgvvialst...lleeeeakvllrvkqlvkalesal.............nveeeqlkkereleekleelreelepleekkeeidekAerrtrrll 92 
                 +lse+ + + ++    +l ++++++ ++ +q v++  ++l              +++e+++ + +++ +le +++e++ +e + +ei++k++++++ ++
  EEA20721.1  10 TLSEEYQNLQAELetiILARQKLESQQQENQAVQQEFASLdddsniyklvgpvLLKQEKSEAVMAVDGRLEFIEKEIKRIEGQIQEINNKSDKKRTEII 108
                 555554444444333433333333333333333333333344444455556556888999999999***************************998876 PP

>> BRE1  BRE1 E3 ubiquitin ligase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   7.0      0.47   2.2e+02       2      56 ..       5      48 ..       1      57 [. 0.43
   2 ?   10.6   2.3   0.00095      0.45       2      35 ..      83     116 ..      82     120 .. 0.93

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.47
        BRE1  2 qkELvklekafeelseqlskkvkeltileekklrleaekakadqkyfaamrskda 56
                qk L+ l++++++l+++l           e ++ + ++ + ++q+  a++ +  +
  EEA20721.1  5 QKALQTLSEEYQNLQAEL-----------ETIILARQKLESQQQENQAVQQEFAS 48
                233333333333333333...........33444444444444444444444444 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00095
        BRE1   2 qkELvklekafeelseqlskkvkeltileekklr 35 
                 +kE++++e +++e +++ +kk +e+  l++++++
  EEA20721.1  83 EKEIKRIEGQIQEINNKSDKKRTEIIQLQSQVQQ 116
                 79***************************99875 PP

>> OmpH  Outer membrane protein (OmpH-like)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6  13.3    0.0094       4.4      29      87 ..       2      53 ..       1      75 [. 0.58
   2 ?    4.6   7.8     0.081        38      38      78 ..      82     119 ..      64     127 .] 0.60

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0094
                HHHHHHHHHHHHHHHHHHHHHHHHTTTS.-HHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        OmpH 29 kklqaeleakekelqklqeelqkkakklekeekeqelqkkeqelqqkqqqkaqelqkkq 87
                ++ q++l+++ +e+q+lq+el+    +     ++q+l+ ++qe q+  qq++  l + +
  EEA20721.1  2 EQAQKALQTLSEEYQNLQAELE----T--IILARQKLESQQQENQA-VQQEFASLDDDS 53
                4666777777777777777775....2..33345556666666666.666655555444 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.081
                 HHHHHHHHHHHHHHHTTTS.-HHHHHHHHHHHHHHHHHHHH CS
        OmpH  38 kekelqklqeelqkkakklekeekeqelqkkeqelqqkqqq 78 
                  eke+++ + ++q+ ++k  + +k+ e+ +++ ++qq qq 
  EEA20721.1  82 IEKEIKRIEGQIQEINNK--SDKKRTEIIQLQSQVQQ-QQP 119
                 445555555555432233..67778888888888888.443 PP

>> ERM  Ezrin/radixin/moesin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6  19.9      0.44   2.1e+02      22     136 ..       2     117 ..       1     126 [. 0.45

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.44
         ERM  22 ekaqeaLreseetaelLaekarraeeeaelLeqkaaeaeeeiqrlkesaekeeeekeklerklr.eaeleaarleeeserkeeeaerLkeeleeareae 119
                 e+aq+aL+   e+ + L+ +++    ++++Le +++e ++  q+++    +++  k      l+ e+++ +  +    e  e+e +r + +++e++++ 
  EEA20721.1   2 EQAQKALQTLSEEYQNLQAELETIILARQKLESQQQENQAVQQEFASLDDDSNIYKLVGPVLLKqEKSEAVMAVDGRLEFIEKEIKRIEGQIQEINNKS 100
                 555555555555555555555555555555555555555555555555544444444333322202222222222233334445555555555555555 PP

         ERM 120 eeakekllealstpsks 136
                  ++++++ ++ s+ +++
  EEA20721.1 101 DKKRTEIIQLQSQVQQQ 117
                 55554444444444322 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   2.0     0.046        22      47      95 ..       5      52 ..       1      62 [. 0.60
   2 ?    7.2   3.2     0.011       5.1      61     112 ..      65     116 ..      61     120 .. 0.76

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.046
     DUF1664 47 skqleqvseslaatkrhLssridrvdkkldeqkeiskeikeevtevred 95
                 k l+++se+ ++ + +L+  i    +kl++q++  +++++e +++ +d
  EEA20721.1  5 QKALQTLSEEYQNLQAELETII-LARQKLESQQQENQAVQQEFASLDDD 52
                4556666666666666665443.34566666666666666666666555 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.011
     DUF1664  61 krhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeaveg 112
                 k++ s+ +  vd +l+  ++ +k i+ +++e++++ ++ ++++ ++++ v++
  EEA20721.1  65 KQEKSEAVMAVDGRLEFIEKEIKRIEGQIQEINNKSDKKRTEIIQLQSQVQQ 116
                 5555677778888888888888888888888888888888888888887775 PP

>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   2.0      0.27   1.3e+02     192     222 ..      13      46 ..       1      58 [. 0.49
   2 ?    7.8   0.4    0.0039       1.9     126     161 ..      78     115 ..      62     123 .. 0.85

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.27
        CorA 192 eylrdlldeler...llemlealrerleslqdty 222
                 e +++l+ ele    + ++le++++  + +q+++
  EEA20721.1  13 EEYQNLQAELETiilARQKLESQQQENQAVQQEF 46 
                 2233333333333334444444444444444444 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0039
        CorA 126 llekleeeldeledel..edstkkeilrelaqlrrrlv 161
                  le +e+e++++e ++   ++++++ + e++ql+ ++ 
  EEA20721.1  78 RLEFIEKEIKRIEGQIqeINNKSDKKRTEIIQLQSQVQ 115
                 57889***********8888888899999999998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (127 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2900  (0.161749); expected 358.6 (0.02)
Passed bias filter:                      901  (0.0502538); expected 358.6 (0.02)
Passed Vit filter:                       151  (0.00842211); expected 17.9 (0.001)
Passed Fwd filter:                        62  (0.00345808); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              38  [number of targets reported over threshold]
# CPU time: 0.76u 0.34s 00:00:01.10 Elapsed: 00:00:00.50
# Mc/sec: 768.51
//
Query:       EEA20722.1  [L=433]
Description: vacuolar sorting ATPase Vps4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.3e-42  144.6   0.0    4.5e-42  143.6   0.0    1.5  1  AAA              ATPase family associated with various cellul
    1.9e-30  104.6   0.0    7.7e-30  102.7   0.0    2.1  1  Vps4_C           Vps4 C terminal oligomerisation domain
    5.4e-23   80.8   2.2    5.4e-23   80.8   2.2    2.0  1  MIT              MIT (microtubule interacting and transport) 
    1.2e-05   25.1   0.0    2.3e-05   24.2   0.0    1.5  1  RuvB_N           Holliday junction DNA helicase RuvB P-loop d
    1.3e-05   25.7   0.0    0.00016   22.1   0.0    2.5  1  AAA_16           AAA ATPase domain
    2.7e-05   24.2   0.0    0.00012   22.1   0.0    2.2  1  AAA_5            AAA domain (dynein-related subfamily)
      5e-05   23.6   0.0      0.011   16.1   0.0    2.8  2  RNA_helicase     RNA helicase
    7.3e-05   22.6   0.0    0.00016   21.5   0.0    1.6  1  IstB_IS21        IstB-like ATP binding protein
    9.6e-05   21.7   0.0    0.00057   19.1   0.0    2.1  2  DUF815           Protein of unknown function (DUF815)
    0.00012   22.3   0.1      0.019   15.2   0.0    2.5  2  AAA_22           AAA domain
    0.00013   21.3   0.0    0.00024   20.5   0.0    1.4  1  TIP49            TIP49 P-loop domain
    0.00032   20.7   0.0    0.00068   19.7   0.0    1.5  1  AAA_14           AAA domain
    0.00045   20.8   0.1      0.002   18.7   0.0    2.2  1  AAA_18           AAA domain
    0.00075   19.3   0.0      0.025   14.4   0.0    2.6  2  AAA_lid_3        AAA+ lid domain
    0.00095   19.3   0.0     0.0082   16.3   0.0    2.3  2  AAA_2            AAA domain (Cdc48 subfamily)
     0.0017   18.5   0.0     0.0039   17.4   0.0    1.7  1  AAA_33           AAA domain
     0.0028   17.4   0.1      0.011   15.4   0.0    2.0  2  AAA_24           AAA domain
     0.0051   17.2   0.0      0.037   14.5   0.0    2.4  2  AAA_17           AAA domain
     0.0098   15.5   0.3       0.64    9.6   0.1    2.8  3  AAA_25           AAA domain
  ------ inclusion threshold ------
      0.016   14.7   0.1      0.089   12.3   0.0    2.2  2  AAA_7            P-loop containing dynein motor region
       0.02   14.3   0.1      0.071   12.5   0.1    2.0  2  Mg_chelatase     Magnesium chelatase, subunit ChlI
      0.035   14.2   0.1      0.095   12.8   0.0    1.7  1  Torsin           Torsin
      0.054   12.6   0.0        0.1   11.6   0.0    1.4  1  Parvo_NS1        Parvovirus non-structural protein NS1
      0.059   13.3   0.1        1.3    8.9   0.0    2.4  2  ATPase_2         ATPase domain predominantly from Archaea
      0.061   13.5   1.9       0.13   12.5   1.9    1.6  1  USP8_dimer       USP8 dimerisation domain
      0.079   12.4   0.1       0.16   11.4   0.1    1.4  1  PhoH             PhoH-like protein
      0.083   12.8   0.0       0.67    9.9   0.0    2.1  2  NACHT            NACHT domain
       0.14   11.8   0.0       0.49   10.1   0.0    2.0  1  Sigma54_activat  Sigma-54 interaction domain
       0.14   11.0   0.0       0.29   10.0   0.0    1.5  1  AFG1_ATPase      AFG1-like ATPase
       0.17   11.6   1.7       0.51   10.0   0.0    2.5  2  Cytidylate_kin   Cytidylate kinase
       0.19   11.5   0.8       0.34   10.6   0.8    1.4  1  Use1             Membrane fusion protein Use1
       0.22   10.8   0.2        8.5    5.6   0.0    2.7  3  ATPase           KaiC


Domain annotation for each model (and alignments):
>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  143.6   0.0     8e-45   4.5e-42       1     131 [.     167     295 ..     167     296 .. 0.98

  Alignments for each domain:
  == domain 1  score: 143.6 bits;  conditional E-value: 8e-45
                 EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTS CS
         AAA   1 vllyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksrsgseseeeervvnqLlteldgvkkk 99 
                 +llyGppGtGK++lakava+e++++f+++s s+l+sk++gese+ +++lf+ a+e++ p i+fiDE+dal++ r ++ese ++r+  +Ll ++dgv k+
  EEA20722.1 167 ILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSKWMGESERLVKQLFNMARENK-PAIIFIDEVDALCGPRGEGESEASRRIKTELLVQMDGVGKD 264
                 69******************************************************8.****************999********************** PP

                 SSTEEEEEEESSGGGSTHHHHSTTSSEEEETT CS
         AAA 100 eskvivigatnrpdkldpallrgRfdrkieie 131
                 ++ v+++gatn p++ld a++ +Rf+r+i+i+
  EEA20722.1 265 SRGVLILGATNIPWQLDAAIR-RRFQRRIHIS 295
                 *********************.7******997 PP

>> Vps4_C  Vps4 C terminal oligomerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.7   0.0   1.4e-32   7.7e-30       1      61 []     369     429 ..     369     429 .. 0.99

  Alignments for each domain:
  == domain 1  score: 102.7 bits;  conditional E-value: 1.4e-32
      Vps4_C   1 ltPCspgdpgaiemtwmdipsdkllePpvtlkDflkalkkarptVskeDLekheeFTkefG 61 
                 ltPCspgd ga+em+wm+++s+kllePp+ lkDf+ka++++rptVs eDLe++ e+T++fG
  EEA20722.1 369 LTPCSPGDNGAMEMNWMEVESEKLLEPPLVLKDFIKAIRNSRPTVSREDLERNAEWTQQFG 429
                 7***********************************************************9 PP

>> MIT  MIT (microtubule interacting and transport) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.8   2.2   9.7e-26   5.4e-23       1      65 []       7      72 ..       7      72 .. 0.97

  Alignments for each domain:
  == domain 1  score: 80.8 bits;  conditional E-value: 9.7e-26
         MIT  1 ldkAlelvkkAveeDnagnyeeAlelYkealelLlqalk.ekneerrellrekieeYleRaeeLke 65
                l +A++ vkkA+e Dnag+ye+A++ Y  alel+++alk ekn++++e++r+k+ eY++Rae+Lk+
  EEA20722.1  7 LGRAIDTVKKAIEHDNAGEYEKAYQGYYAALELFMLALKwEKNPKSKEMIRAKTGEYMDRAEKLKN 72
                568************************************88***********************97 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.2   0.0   4.2e-08   2.3e-05      31      97 ..     162     236 ..     130     293 .. 0.76

  Alignments for each domain:
  == domain 1  score: 24.2 bits;  conditional E-value: 4.2e-08
      RuvB_N  31 ealdhvllyGpPGlGkttlakiiakelgvkl.kitsgPvlek....agdlaalltnleekd...vlfideihrls 97 
                 ++   +llyGpPG Gk+ lak +a+e ++++  ++s+  ++k    +  l+  l n+ +++   ++fide+  l 
  EEA20722.1 162 QPWKGILLYGPPGTGKSYLAKAVATEANSTFfSVSSSDLVSKwmgeSERLVKQLFNMARENkpaIIFIDEVDALC 236
                 566779*********************99872455566665532224568888888865533449*****98875 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.1   0.0   2.9e-07   0.00016      23      96 ..     162     226 ..     156     271 .. 0.62

  Alignments for each domain:
  == domain 1  score: 22.1 bits;  conditional E-value: 2.9e-07
      AAA_16  23 rp.elvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipysalaqalareellrqlldeaesaelea 96 
                 +p   +ll+G++G+GKs l+++++++++ +   f++    +l      s +      e+l++ql ++a++++++ 
  EEA20722.1 162 QPwKGILLYGPPGTGKSYLAKAVATEANST---FFSVSSSDL-----VSKWMGES--ERLVKQLFNMARENKPAI 226
                 567899******************998887...544444444.....12344444..478888888866654443 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.1   0.0   2.2e-07   0.00012       2      75 ..     167     233 ..     166     288 .. 0.88

  Alignments for each domain:
  == domain 1  score: 22.1 bits;  conditional E-value: 2.2e-07
                 EEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--.........--------..G-SEEEEESGG CS
       AAA_5   2 vlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreikngttslvdsplvraar..egeilvlDEve 75 
                 +lL GppGtgKs la+ +a   n++++ v      +++dl+ ++   ++ ++lv++ l + ar  +++i+++DEv+
  EEA20722.1 167 ILLYGPPGTGKSYLAKAVATEANSTFFSV------SSSDLVSKWM--GESERLVKQ-LFNMARenKPAIIFIDEVD 233
                 89*****************9999999976......6889*****9..455555555.5556666899********8 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0     2e-05     0.011       1      26 [.     167     192 ..     167     228 .. 0.78
   2 ?    4.5   0.0     0.081        45       3      26 ..     235     258 ..     234     275 .. 0.85

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 2e-05
  RNA_helicase   1 iwlyGpsgeGKStlakeLakallkkl 26 
                   i+lyGp+g+GKS+lak +a++  +++
    EEA20722.1 167 ILLYGPPGTGKSYLAKAVATEANSTF 192
                   789**************888877655 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.081
  RNA_helicase   3 lyGpsgeGKStlakeLakallkkl 26 
                   l+Gp+geG S +++++ ++ll ++
    EEA20722.1 235 LCGPRGEGESEASRRIKTELLVQM 258
                   79***************9999777 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.0   2.9e-07   0.00016      49      90 ..     166     204 ..     157     244 .. 0.69

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 2.9e-07
   IstB_IS21  49 nivllGpsGvGKshlaialgveavraglsvlfvrvedLveel 90 
                 +i+l Gp+G+GKs+la a+++ea  + +sv   + +dLv++ 
  EEA20722.1 166 GILLYGPPGTGKSYLAKAVATEANSTFFSV---SSSDLVSKW 204
                 799****************99987666665...456666654 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.0      0.19   1.1e+02     120     144 ..     105     129 ..     103     132 .. 0.89
   2 !   19.1   0.0     1e-06   0.00057      21     115 ..     124     231 ..     110     254 .. 0.73

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.19
      DUF815 120 eeeeeyksLksvLeGsleakpenvl 144
                  e++e+k+L+ +L+G++ ++  nv+
  EEA20722.1 105 GEDAEAKKLRGALQGAILSEKPNVR 129
                 57899************99999985 PP

  == domain 2  score: 19.1 bits;  conditional E-value: 1e-06
      DUF815  21 evdevklddLvgidkqkealvente......qfl..eglpannvLLwGarGtGKSslvkallneyaeeg..Lrlievekedlkelpklvellr...erp 106
                 e  +v+++d+ g+++ keal+e +       ++   + +p + +LL+G  GtGKS l ka+ +e++++   +   ++  + + e ++lv++l    +++
  EEA20722.1 124 EKPNVRWEDVAGLENAKEALKEAVIlpikfpHLFtgKRQPWKGILLYGPPGTGKSYLAKAVATEANSTFfsVSSSDLVSKWMGESERLVKQLFnmaREN 222
                 5567888999999999999988864222121233124467899**********************9998443334566666777777777765222556 PP

      DUF815 107 erfilfvDD 115
                 +  i+f+D 
  EEA20722.1 223 KPAIIFIDE 231
                 678888886 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   3.4e-05     0.019       8      30 ..     167     189 ..     164     203 .. 0.86
   2 ?    4.5   0.0     0.071        40      74     105 ..     207     239 ..     196     276 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 3.4e-05
      AAA_22   8 lvvtGesGtGKTtllrrlleqld 30 
                 ++++G++GtGK++l++ ++ +++
  EEA20722.1 167 ILLYGPPGTGKSYLAKAVATEAN 189
                 799***************99873 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.071
      AAA_22  74 sseellealeqalraravielliiDEaqhlr..s 105
                 +se+l+++l + +r+ +  +++ iDE++ l   +
  EEA20722.1 207 ESERLVKQLFNMARENKP-AIIFIDEVDALCgpR 239
                 567888888888888888.9********996542 PP

>> TIP49  TIP49 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5   0.0   4.2e-07   0.00024      42     103 ..     156     215 ..     113     222 .. 0.79

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 4.2e-07
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49  42 likekklaGravLlaGpsgtGktalaiaiskelgedvpfvalsgsevyslevkktevltqal 103
                 l   k+   +++Ll Gp+gtGk+ la a++ e +    f ++s+s++ s  +  +e l+++l
  EEA20722.1 156 LFTGKRQPWKGILLYGPPGTGKSYLAKAVATEAN--STFFSVSSSDLVSKWMGESERLVKQL 215
                 5556666779*********************987..67999**************9998765 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.0   1.2e-06   0.00068       5      75 ..     167     234 ..     164     260 .. 0.86

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 1.2e-06
      AAA_14   5 lvitGaRrvGKTtllkqlikellvkkesilyinldderdkkladpekllelileklkeekktylflDEiqe 75 
                 +++ G+  +GK++l+k ++ e     + ++ ++  d   k + ++e+l + ++++++e+k  ++f+DE+  
  EEA20722.1 167 ILLYGPPGTGKSYLAKAVATEAN---STFFSVSSSDLVSKWMGESERLVKQLFNMARENKPAIIFIDEVDA 234
                 7899**************98888...889999988888888888888898888887677999******976 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   3.5e-06     0.002       1      42 [.     167     211 ..     167     244 .. 0.78

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 3.5e-06
      AAA_18   1 IlltGtpGvGKttlakeLskrlgf...gvnlrdvakenglllevd 42 
                 Ill G+pG+GK+ lak+++ + ++   +v ++d++++ + + e+ 
  EEA20722.1 167 ILLYGPPGTGKSYLAKAVATEANStffSVSSSDLVSKWMGESERL 211
                 99****************999766889888888887765555554 PP

>> AAA_lid_3  AAA+ lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.0   4.5e-05     0.025       3      34 ..     321     352 ..     320     362 .. 0.90
   2 ?    1.8   0.0      0.38   2.1e+02      28      44 ..     403     419 ..     397     420 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 4.5e-05
   AAA_lid_3   3 dlkeLAerTeGySGADlaalcreAallAlrrg 34 
                 d+ +LAe ++ ySG D++  ++ A +  +r  
  EEA20722.1 321 DYRHLAEISAEYSGSDISIAVQDALMQPIRKI 352
                 7789**********************999975 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.38
   AAA_lid_3  28 llAlrrgikeitmedfe 44 
                 + A+r ++++++ ed+e
  EEA20722.1 403 IKAIRNSRPTVSREDLE 419
                 78*************98 PP

>> AAA_2  AAA domain (Cdc48 subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0       1.5   8.6e+02      30      65 ..      50      87 ..      28      91 .. 0.70
   2 !   16.3   0.0   1.5e-05    0.0082       6      92 ..     167     248 ..     162     265 .. 0.72

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 1.5
                ....-EEEEEGGG---.----T.HHHHHHHHHTTT-HH CS
       AAA_2 30 kkekkliradaselle.eeeve.hlvsrligappgyvg 65
                 k+k++ira   e++  +e+++ hl + +  ++p  vg
  EEA20722.1 50 PKSKEMIRAKTGEYMDrAEKLKnHLANADNKKKPSAVG 87
                5789999**999**996555541555556666666665 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 1.5e-05
                 EEEE--TTSSHHHHHHHHHHHTT-....-EEEEEGGG---..----THHHHHHHHHTTT-HHHHTTSEEEEETGGG----.--------- CS
       AAA_2   6 illlgptgvGktelakalaellfvkkekkliradaselle..eeevehlvsrligappgyvgaeegGivllDEidKihpk.essgadvSr 92 
                 ill gp g+Gk++laka+a   +     ++  +  s+l      e+e+lv++l   +    + ++  i+++DE+d  +   ++ +++ Sr
  EEA20722.1 167 ILLYGPPGTGKSYLAKAVATEANS----TFFSVSSSDLVSkwMGESERLVKQLFNMA----RENKPAIIFIDEVDALCGPrGEGESEASR 248
                 899*******************93....66666666666633356667776666543....444556********998765555555555 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.0   6.9e-06    0.0039       2      33 ..     167     211 ..     167     294 .. 0.81

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 6.9e-06
      AAA_33   2 vllvGlpGsGKstlaerllkklg..avllssdt...........l 33 
                 +ll G+pG+GKs+la+ ++ +    ++ +ss +           l
  EEA20722.1 167 ILLYGPPGTGKSYLAKAVATEANstFFSVSSSDlvskwmgeserL 211
                 6789**************988888888888888344444444443 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.1       3.2   1.8e+03      84     112 ..      10      38 ..       4      79 .. 0.69
   2 !   15.4   0.0     2e-05     0.011       5      31 ..     167     195 ..     165     248 .. 0.64

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 3.2
      AAA_24  84 evirqnekaeskedkgdgkGygelaeefr 112
                  +++ +++ e+ + + + k+y+ + + + 
  EEA20722.1  10 AIDTVKKAIEHDNAGEYEKAYQGYYAALE 38 
                 55666667677766666666665544444 PP

  == domain 2  score: 15.4 bits;  conditional E-value: 2e-05
      AAA_24   5 iliyGpsgiGKTtlakel..gpkplfidt 31 
                 il+yGp+g+GK++lak    + +  f+ +
  EEA20722.1 167 ILLYGPPGTGKSYLAKAVatEANSTFFSV 195
                 89**************9966444444444 PP

>> AAA_17  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.0   6.6e-05     0.037       1      43 [.     170     215 ..     170     232 .. 0.75
   2 ?   -1.5   0.0       5.6   3.1e+03      57      78 ..     344     365 ..     324     369 .. 0.68

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 6.6e-05
                 EE-TTSSHHHHHHHHHHHHTEEEE..EHHHHHHHHHHTTT.SHSSH CS
      AAA_17   1 lGgPGsGKgtqceklvekygfthl..saGdllreeakrgg.lakar 43 
                 +G+PG GK+ +++ ++ + + t++  s +dl+ + + +++ l+k+ 
  EEA20722.1 170 YGPPGTGKSYLAKAVATEANSTFFsvSSSDLVSKWMGESErLVKQL 215
                 7*****************9888751166899888776665245554 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 5.6
                 HHHHHHHHHHHHHHSSEEEEEE CS
      AAA_17  57 lqkeaaekiaeeakkkgvlvdg 78 
                  + + ++ki+ +   k+vlvdg
  EEA20722.1 344 ALMQPIRKIQTATHYKKVLVDG 365
                 2334445666666889999998 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.1    0.0011      0.64      36      54 ..     167     185 ..     156     194 .. 0.88
   2 ?    2.7   0.0      0.15        84     128     167 ..     210     248 ..     191     258 .. 0.80
   3 ?   -2.2   0.0       4.7   2.6e+03     125     139 ..     317     331 ..     279     363 .. 0.57

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0011
      AAA_25  36 allaGapgtGKttlaldla 54 
                 +ll+G+pgtGK+ la  +a
  EEA20722.1 167 ILLYGPPGTGKSYLAKAVA 185
                 69************97776 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.15
      AAA_25 128 advdaleaaieevegvrlvviDplsralggdensnsdvga 167
                 + v++l + ++e ++++ + iD +++++g   + +s++++
  EEA20722.1 210 RLVKQLFNMARE-NKPAIIFIDEVDALCGPRGEGESEASR 248
                 567888899999.88**************97777777643 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 4.7
      AAA_25 125 lltadvdaleaaiee 139
                 l++ad+++l++   e
  EEA20722.1 317 LTQADYRHLAEISAE 331
                 344555555555544 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   0.00016     0.089      34     109 ..     165     232 ..     155     236 .. 0.65
   2 ?   -1.9   0.0       3.5     2e+03     149     175 ..     268     294 ..     263     295 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00016
       AAA_7  34 kpvllvGptGtGKtviikdllkkldkekylsltinfsaqtsanqlqdiiesklekrrkgvy.gPpggkklvvFvDDl 109
                 k +ll+Gp GtGK+ ++k + ++ +++ ++          s+++l +  + + e+  k+++ ++  +k  ++F+D++
  EEA20722.1 165 KGILLYGPPGTGKSYLAKAVATEANSTFFS--------V-SSSDLVSKWMGESERLVKQLFnMARENKPAIIFIDEV 232
                 569***************999888832222........2.2333333344445555555552345666677777765 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 3.5
       AAA_7 149 vqlvaamgppgggrneitpRllrhfnv 175
                 v +++a + p +    i  R++r++++
  EEA20722.1 268 VLILGATNIPWQLDAAIRRRFQRRIHI 294
                 778899999999999********9875 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.1   0.00013     0.071      25      43 ..     167     185 ..     130     191 .. 0.90
   2 ?   -3.3   0.0       8.3   4.7e+03      27      44 ..     235     252 ..     234     259 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00013
  Mg_chelatase  25 lllvGppGsGKtmlakrlp 43 
                   +ll+GppG+GK+ lak+++
    EEA20722.1 167 ILLYGPPGTGKSYLAKAVA 185
                   89*************9976 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 8.3
  Mg_chelatase  27 lvGppGsGKtmlakrlps 44 
                   l+Gp G G +   +r+++
    EEA20722.1 235 LCGPRGEGESEASRRIKT 252
                   789******999999975 PP

>> Torsin  Torsin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   0.00017     0.095      44      93 ..     155     207 ..     138     216 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 0.00017
                 HHT-SS-SS-EEEEEEE-TTSSHHHHHHHHH...HHHSTTGGGSTTEEEEEHH CS
      Torsin  44 ylenekpkkpLvlsfhGwtGtGknfvaeiia...enlyrdGlrsdyvkkfvat 93 
                 +l + k +    + ++G +GtGk+++a+ +a   + ++ + + sd v k+++ 
  EEA20722.1 155 HLFTGKRQPWKGILLYGPPGTGKSYLAKAVAteaNSTFFSVSSSDLVSKWMGE 207
                 5555544444456689************9963336789999999999998765 PP

>> Parvo_NS1  Parvovirus non-structural protein NS1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   0.00019       0.1     112     136 ..     162     186 ..     152     196 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00019
   Parvo_NS1 112 gkrntvwfyGpantGktnlaeaIak 136
                 ++   +++yGp+ tGk++la+a a+
  EEA20722.1 162 QPWKGILLYGPPGTGKSYLAKAVAT 186
                 5556799***************986 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.0    0.0023       1.3      17      45 ..     161     189 ..     158     197 .. 0.86
   2 ?    1.6   0.0       0.4   2.2e+02     111     131 ..     216     236 ..     190     244 .. 0.71

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0023
    ATPase_2  17 repneiyfiYGpegsGKtaLlkeiienle 45 
                 r+p++ +++YGp g GK+ L k ++++ +
  EEA20722.1 161 RQPWKGILLYGPPGTGKSYLAKAVATEAN 189
                 7889999***************9988764 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.4
    ATPase_2 111 ekikkkgkkiiiiiDelqkli 131
                  ++ ++ k  ii+iDe+  l 
  EEA20722.1 216 FNMARENKPAIIFIDEVDALC 236
                 345566677889999997765 PP

>> USP8_dimer  USP8 dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   1.9   0.00023      0.13      37     111 ..       9      77 ..       1      81 [. 0.81

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00023
  USP8_dimer  37 saeklfkkAeeyrlegdeEkAYvlymkylnllelIrkksdykekkasvkellgdkkankvildklekLkesLkkr 111
                 +a   +kkA e+   g+ EkAY  y   l l+ l  k ++  + k+++++     k  ++ +d++ekLk+ L + 
  EEA20722.1   9 RAIDTVKKAIEHDNAGEYEKAYQGYYAALELFMLALKWEKNPKSKEMIRA-----KTGEY-MDRAEKLKNHLANA 77 
                 6667799*************************887777666666666666.....45678.8*********9875 PP

>> PhoH  PhoH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1   0.00029      0.16      23      43 ..     168     188 ..     164     195 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00029
                 EEE--TTSSTTHHHHHHHHHH CS
        PhoH  23 faiGpaGtGKtylavalavea 43 
                    Gp GtGK+yla a+a ea
  EEA20722.1 168 LLYGPPGTGKSYLAKAVATEA 188
                 568**************9887 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0    0.0012      0.67       3      25 ..     167     189 ..     165     198 .. 0.90
   2 ?    0.4   0.0      0.95   5.3e+02      56     100 ..     199     245 ..     189     258 .. 0.64

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.0012
                 EEEEC-TTTCHHHHHHHHHHHHC CS
       NACHT   3 vilqGeaGsGKTtLlqklalawa 25 
                 ++l G++G GK++L++ +a+++ 
  EEA20722.1 167 ILLYGPPGTGKSYLAKAVATEAN 189
                 7899**************99875 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.95
                 HHHCCCCTS--SSS-CCHHHHCCSCCCEEEEEE-STT-SS-TCH.... CS
       NACHT  56 dllfsqlpepaapvsevwavllelperlLlilDglDelvtdlgq...k 100
                 dl+ + + e+++ v++   ++++  + + + +D +D l+   g+   +
  EEA20722.1 199 DLVSKWMGESERLVKQ-LFNMARENKPAIIFIDEVDALCGPRGEgesE 245
                 5555555666667777.555566666666778****999988884321 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   0.00088      0.49      25      56 ..     167     195 ..     158     237 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00088
                      EEEECSTTSSHHHHHHHHHHHSTTTTS-EEEE CS
  Sigma54_activat  25 vlitGesGtGKellaraiheaskrkekpfvav 56 
                      +l+ G  GtGK++la+a+ ++ +   + f +v
       EEA20722.1 167 ILLYGPPGTGKSYLAKAVATEAN---STFFSV 195
                      89**************9976543...445555 PP

>> AFG1_ATPase  AFG1-like ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00052      0.29      47      80 ..     152     182 ..     124     220 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00052
  AFG1_ATPase  47 algklfgrkrksvepvrglYlwGgvGrGKtylmd 80 
                  ++ +lf++kr   +p +g+ l+G+ G GK+yl  
   EEA20722.1 152 KFPHLFTGKR---QPWKGILLYGPPGTGKSYLAK 182
                  5668899997...9*****************965 PP

>> Cytidylate_kin  Cytidylate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0    0.0009      0.51       3      29 ..     169     195 ..     167     200 .. 0.88
   2 ?   -0.2   0.3       1.2     7e+02     148     148 ..     292     292 ..     234     369 .. 0.61

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.0009
                     EE-STTSSHHHHHHHHHHHHT-EEEEH CS
  Cytidylate_kin   3 iDGPagsGKssvaralaeklglkyldt 29 
                     + GP g+GKs +a+a+a++ + ++++ 
      EEA20722.1 169 LYGPPGTGKSYLAKAVATEANSTFFSV 195
                     67******************9999875 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 1.2
                     H CS
  Cytidylate_kin 148 l 148
                     +
      EEA20722.1 292 I 292
                     3 PP

>> Use1  Membrane fusion protein Use1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.8   0.00061      0.34      29     110 ..      31     114 ..      13     146 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00061
        Use1  29 ekyvkaleemleeLkkesskpskevlk....eYsekveaLkllleaeklssteekalanqllapgeeskeekeeskereeaskelr 110
                 + y +ale ++ +Lk e++++ske+++    eY  + e Lk+ l+++ ++++   + an ++a+g  s + ke+++ ++ ++k+lr
  EEA20722.1  31 QGYYAALELFMLALKWEKNPKSKEMIRaktgEYMDRAEKLKNHLANADNKKKPSAVGANGKVANG--SGKGKEDEDGEDAEAKKLR 114
                 458999*****************999766669*************99999666666688888888..3333333344445555555 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0     0.015       8.5      21      38 ..     166     183 ..     152     192 .. 0.83
   2 ?    2.3   0.0      0.16        90     103     152 ..     207     259 ..     185     271 .. 0.78
   3 ?   -2.8   0.0       5.9   3.3e+03     105     126 ..     343     364 ..     321     369 .. 0.74

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.015
      ATPase  21 vvlitGepGtGKtifalq 38 
                  +l++G pGtGK+ +a+ 
  EEA20722.1 166 GILLYGPPGTGKSYLAKA 183
                 589**********99975 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.16
      ATPase 103 dleelieelaeaikeikakrvviDsitgl...ayeekeavaReilrqlvrvlk 152
                 + e l+++l ++ +e k   + iD +++l     e +++  R+i  +l+ ++ 
  EEA20722.1 207 ESERLVKQLFNMARENKPAIIFIDEVDALcgpRGEGESEASRRIKTELLVQMD 259
                 56889999999***************999644455566667777777776665 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 5.9
      ATPase 105 eelieelaeaikeikakrvviD 126
                 ++l++ ++++  +++ k+v++D
  EEA20722.1 343 DALMQPIRKIQTATHYKKVLVD 364
                 5778888888888888999888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (433 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       612  (0.0341346); expected 358.6 (0.02)
Passed bias filter:                      513  (0.0286129); expected 358.6 (0.02)
Passed Vit filter:                       106  (0.00591221); expected 17.9 (0.001)
Passed Fwd filter:                        32  (0.00178482); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              32  [number of targets reported over threshold]
# CPU time: 0.68u 0.33s 00:00:01.01 Elapsed: 00:00:00.50
# Mc/sec: 2609.02
//
Query:       EEA20723.1  [L=989]
Description: IQ calmodulin-binding motif domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.2e-115  387.1   0.4   1.2e-115  387.1   0.4    3.2  3  Tcp11     T-complex protein 11
  ------ inclusion threshold ------
        9.6    6.3  12.6         29    4.7   8.8    2.4  2  UPF0242   Uncharacterised protein family (UPF0242) N-terminus


Domain annotation for each model (and alignments):
>> Tcp11  T-complex protein 11
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -9.6  14.3         2   1.8e+04     345     403 ..     117     171 ..      47     355 .. 0.60
   2 ?   -2.2   0.1      0.19   1.7e+03     186     215 ..     443     470 ..     403     523 .. 0.56
   3 !  387.1   0.4  1.3e-119  1.2e-115       1     441 [.     529     983 ..     529     984 .. 0.94

  Alignments for each domain:
  == domain 1  score: -9.6 bits;  conditional E-value: 2
       Tcp11 345 empeaakawLskqlqkvlsksdpvfkllesrvrkalearllassasekvretstasekl 403
                 e++  + a  ++ +++ l+ ++  + l  ++ r++l+a ++a +++ +vr ++++ e++
  EEA20723.1 117 EKVRLRAAVAKAATRN-LQREE--RALAAQQARERLLAEITA-KCEDEVRRAKKKAEET 171
                 3333222222222222.23344..666666666666666666.2222222222222211 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.19
       Tcp11 186 islestrkWlrkarekleaesserdpesss 215
                   l++ ++ lrka+++  ++  +++++s+ 
  EEA20723.1 443 KALDMVKQALRKAKRE--KKHLKSSKQSIP 470
                 4566666666666211..111111222221 PP

  == domain 3  score: 387.1 bits;  conditional E-value: 1.3e-119
       Tcp11   1 LrheilfDpelqfrpnldgeegrvketmakayWdaleeelekdppdysrllallkelrdiLlslv..pnslrqeieevLDldlleqqlekgvldlekla 97 
                 L+he+l+++e+++++   g++++ +++++k++ d+++++++  + ++++++a+++ ++d+Ll+ +  +nsl+  i+e+LD++l+e+q+e+g++++++++
  EEA20723.1 529 LVHELLINREFRIEQ---GQYTEPRQQIMKHMTDMMRSDVD-AGLGTKWIVAMATVIQDRLLRSLraGNSLHVLISEALDPKLIENQCEAGTFSYDSFF 623
                 8*************9...***********************.88******************************************************* PP

       Tcp11  98 ewlanllkklCAPmRDeevdkmvekiseaseessvdklVegLrelfeiLelMklDvaNhqirllrplLietaveyErkkFqerlesgkislestrkWlr 196
                 ++++++l++lCAP+RD+ev++++e+ s        ++++++L +l++i++l++lD++N++i++++p+Li++a+ yE+++Fq+ le+g+i+le+t+++++
  EEA20723.1 624 DFMSRILPQLCAPFRDPEVKAFAENKS--------GDPIDRLSRLMGIIDLLSLDHTNFMIQVAAPQLIQEAPGYEQRTFQKGLEDGTIKLERTKRFWQ 714
                 ***************************........99************************************************************** PP

       Tcp11 197 karekleaesserdpesssssssassspspskvliqglldllsssadpsseeefPetLalDhaRLrelradlrqlvvlasclllfkqlvkrdvsssvsr 295
                 k+++ + +e+++rdpe +++++    +p + kv++qgl+d+++ +  p++++ +PetL+lD aRL++l+  + +++++a++ll++k+l+krd+     r
  EEA20723.1 715 KNHNLVVDEMKRRDPEIAERRQV---QPPAAKVYAQGLVDIVLNN-APVPSDLVPETLELDNARLEKLHMTAFKIAATAAILLTAKNLLKRDS-----R 804
                 ****************9986554...7777**************8.5999999***************************************9.....8 PP

       Tcp11 296 sslkklkeeilalledeesesgerwtesi..aleiarevskslkessalpdempeaakawLskqlqkvl.............................. 362
                 s++k+++++il+l  +e   ++    e+i  ++e++r               mp+aa+++L +++++vl                              
  EEA20723.1 805 SQWKAEADRILSLDFTEI--KP----ERIqsIIESTRP--------------MPAAARSQLLSMMRRVLspvamattsvdnplssqmpsveyvsghiss 883
                 9***************97..44....444445566666..............78888888888888888888888888888888888888888888888 PP

       Tcp11 363 .....................sksdpvfkllesrvrkalearllassasekvretstasekllpaGlsefveeveelaerlaklvsvhwrvfgplYeei 440
                                      s++dpv +l+ sr+r ++++rl+a+sase+vr+t+tas++l++aG++efv+ev +l+++l k++ v+w+++g +Ye++
  EEA20723.1 884 sssassgststgtesptstssSFTDPVARLILSRLRAHVLSRLSAASASERVRATTTASQSLAAAGMPEFVNEVGKLVDELGKVRDVDWTCHGLVYERV 982
                 89***********************************************************************************************98 PP

       Tcp11 441 l 441
                 +
  EEA20723.1 983 I 983
                 6 PP

>> UPF0242  Uncharacterised protein family (UPF0242) N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   8.8    0.0032        29      78     158 ..     127     204 ..      91     210 .. 0.79
   2 ?    2.6   0.1     0.014   1.3e+02     103     131 ..     443     471 ..     376     518 .. 0.71

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.0032
     UPF0242  78 teldeglktkeealeelqeeeeeLkeeldakeeelerlkeenqqLqekleaiaedfeelkleleeqLaekqellqeyqeti 158
                 ++   +l+ +e al   q++e+ L+e  ++ e e++r k++ ++ + +l+a  + +++l+le+ e+ ae +++  +yq+t 
  EEA20723.1 127 KAATRNLQREERALAAQQARERLLAEITAKCEDEVRRAKKKAEETR-ELKA--AKYARLRLEMAEKFAEAEKRRLQYQQTH 204
                 3333678899999999999999999999999999999999999888.4444..69******************99***986 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.014
     UPF0242 103 eeldakeeelerlkeenqqLqekleaiae 131
                 + ld  +++l++ k+e+++L++ ++ i +
  EEA20723.1 443 KALDMVKQALRKAKREKKHLKSSKQSIPR 471
                 33667777777777777777777766544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (989 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1580  (0.0881254); expected 358.6 (0.02)
Passed bias filter:                      483  (0.0269396); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.87u 0.30s 00:00:01.17 Elapsed: 00:00:00.49
# Mc/sec: 6011.96
//
Query:       EEA20724.1  [L=439]
Description: WD repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.8e-32  109.5  22.4    2.6e-07   31.2   0.0    8.1  7  WD40         WD domain, G-beta repeat
    3.9e-11   43.1   4.8      0.082   13.2   0.1    5.9  6  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
  ------ inclusion threshold ------
      0.074   13.2   0.1          2    8.6   0.0    3.1  3  PCSK9_C1     Proprotein convertase subtilisin-like/kexin type
        0.3   11.6   2.2       0.61   10.6   0.4    2.3  2  GOLD_2       Golgi-dynamics membrane-trafficking


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.9   0.0   0.00015      0.69      18      37 ..      23      42 ..       5      43 .. 0.85
   2 !    6.5   0.1    0.0036        16       9      37 ..      56      93 ..      47      94 .. 0.70
   3 !   27.8   0.6     7e-10   3.1e-06       7      37 ..     131     162 ..     126     163 .. 0.92
   4 !   31.2   0.0   5.7e-11   2.6e-07       3      37 ..     174     209 ..     172     210 .. 0.91
   5 !   18.4   1.2   6.7e-07     0.003       4      37 ..     219     282 ..     216     283 .. 0.74
   6 !    9.4   0.0   0.00045         2       9      37 ..     324     353 ..     316     353 .. 0.83
   7 !   14.2   0.2   1.4e-05     0.061       9      38 .]     395     435 ..     386     435 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00015
                EETTSSEEEEEETTSEEEEE CS
        WD40 18 fspdgawlasGsdDgtvriW 37
                 +p+ +++a++s D+tvri+
  EEA20724.1 23 PHPSLPLVATSSADKTVRIY 42
                6788899****9*******8 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0036
                SS.SSEEEEEEETTSSE........EEEEETTSEEEEE CS
        WD40  9 GH.ssvtslafspdgaw........lasGsdDgtvriW 37
                GH  sv+s a+ p  +         la+Gs D tv iW
  EEA20724.1 56 GHkRSVRSSAWKPTASAgatkgesvLATGSFDATVGIW 93
                785558777444444447777888799*********** PP

  == domain 3  score: 27.8 bits;  conditional E-value: 7e-10
                 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 
                 l+GH s v sl++s +g++la++s+D+++ iW
  EEA20724.1 131 LDGHdSEVKSLSWSASGSLLATCSRDKSIWIW 162
                 68**777************************* PP

  == domain 4  score: 31.2 bits;  conditional E-value: 5.7e-11
                 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 
                 ++ +l  H  +v ++a++p    lasGs+D t+riW
  EEA20724.1 174 TVAVLQEHsADVKCVAWHPTEECLASGSYDDTIRIW 209
                 6788999*777************************* PP

  == domain 5  score: 18.4 bits;  conditional E-value: 6.7e-07
                 EEEEESS.SSEEEEE.............................EETTSSEEEEEETTSEEEEE CS
        WD40   4 lrtltGH.ssvtsla.............................fspdgawlasGsdDgtvriW 37 
                 +  l+GH + v+sl+                             f  +g+ +as+s D+tvriW
  EEA20724.1 219 VACLKGHtGTVWSLDwegvdcspfhpvtvpaddsakikqeykdhFALSGPRIASCSADQTVRIW 282
                 56799**766****7777777677777666666666666666666666666************* PP

  == domain 6  score: 9.4 bits;  conditional E-value: 0.00045
                 SSSS..EEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   9 GHss..vtslafspdgawlasGsdDgtvriW 37 
                 +H +  ++++a+s+ + ++as + Dg + ++
  EEA20724.1 324 AH-DlaIYAVAWSRRSGLVASTGADGRIVVY 353
                 67.4459************97777***9886 PP

  == domain 7  score: 14.2 bits;  conditional E-value: 1.4e-05
                 SSSS...EEEEEEETTSSE.........EEEEETTSEEEEEE CS
        WD40   9 GHss...vtslafspdgaw.........lasGsdDgtvriWd 38 
                 +H +   v+++a+ + g+          l+s +dDg+v++W+
  EEA20724.1 395 AH-GiyeVNHIAWAKRGDRrgsqadeeiLISTGDDGSVKVWS 435
                 56.3356899986666666777788887776677*******5 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.2   0.0    0.0028        13       7      49 ..      27      69 ..      24      93 .. 0.77
   2 !   13.2   0.1   1.8e-05     0.082      35      65 ..     132     162 ..     124     169 .. 0.87
   3 !   13.2   0.1   1.8e-05     0.082      32      66 ..     178     210 ..     169     237 .. 0.76
   4 ?   -3.3   0.0       2.7   1.2e+04      53      67 ..     270     284 ..     263     299 .. 0.63
   5 ?    2.7   0.0     0.034   1.5e+02      35      65 ..     323     353 ..     312     355 .. 0.88
   6 ?    3.9   0.2     0.015        68      23      68 ..     383     437 ..     375     439 .] 0.67

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0028
  ANAPC4_WD40  7 mDLiAlatedgellvfRlngqrvwtleedkedsevrsLaWkpd 49
                   L+A  ++d+ ++++ l   ++ ++ + +++++vrs aWkp 
   EEA20724.1 27 LPLVATSSADKTVRIYSLVNYKLLSVISGGHKRSVRSSAWKPT 69
                 5577888888888888887777777777788888888888775 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 1.8e-05
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdgevrll 65 
                  d++dsev+sL+W+ +g+lLa    d ++ + 
   EEA20724.1 132 DGHDSEVKSLSWSASGSLLATCSRDKSIWIW 162
                  789******************9999988775 PP

  == domain 3  score: 13.2 bits;  conditional E-value: 1.8e-05
  ANAPC4_WD40  32 leedkedsevrsLaWkpdgklLavaysdgevrlld 66 
                  l  ++++  v+++aW+p ++ La +  d ++r+  
   EEA20724.1 178 L--QEHSADVKCVAWHPTEECLASGSYDDTIRIWR 210
                  4..678899***********************974 PP

  == domain 4  score: -3.3 bits;  conditional E-value: 2.7
  ANAPC4_WD40  53 Lavaysdgevrllda 67 
                  +a   +d +vr+   
   EEA20724.1 270 IASCSADQTVRIWRR 284
                  555555666665544 PP

  == domain 5  score: 2.7 bits;  conditional E-value: 0.034
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdgevrll 65 
                  +++d  + ++aW+    l a   +dg++ ++
   EEA20724.1 323 AAHDLAIYAVAWSRRSGLVASTGADGRIVVY 353
                  57899999******************99876 PP

  == domain 6  score: 3.9 bits;  conditional E-value: 0.015
  ANAPC4_WD40  23 RlngqrvwtleedkedsevrsLaW.........kpdgklLavaysdgevrlldae 68 
                   ++++ v t+e+++   ev+++aW         + d+++L    +dg+v++ ++e
   EEA20724.1 383 KTEWKIVATIEAAHGIYEVNHIAWakrgdrrgsQADEEILISTGDDGSVKVWSIE 437
                  6789999999989999999999992222222222345666666666666666665 PP

>> PCSK9_C1  Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.31   1.4e+03      21      43 ..      66      88 ..      57     110 .. 0.78
   2 ?   -0.5   0.0       0.3   1.4e+03      26      61 ..     184     221 ..     174     226 .. 0.69
   3 ?    8.6   0.0   0.00046         2      12      59 ..     333     381 ..     323     418 .. 0.82

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.31
    PCSK9_C1 21 rsatavarCaadeellsCssfsr 43
                 + ta a  +++e +l+  sf  
  EEA20724.1 66 WKPTASAGATKGESVLATGSFDA 88
                45688889999999999999964 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.3
    PCSK9_C1  26 varC...aadeellsCssfsrsGkrrGerievreGrkeC 61 
                  ++C   +++ee l+  s+ ++ + + e i+   G+ +C
  EEA20724.1 184 DVKCvawHPTEECLASGSYDDTIRIWREDIDDW-GQVAC 221
                 444422268999999999998888777777653.55555 PP

  == domain 3  score: 8.6 bits;  conditional E-value: 0.00046
    PCSK9_C1  12 vWsaksgstrsatavarCaadeellsCssfs.rsGkrrGerievreGrk 59 
                  Ws++sg   s+ a  r     e++  ss s ++  ++G+++++ e  k
  EEA20724.1 333 AWSRRSGLVASTGADGRIVVYAEFFVPSSPSsETEAKEGDEMDTSEDTK 381
                 6**********************999999761566799****9887655 PP

>> GOLD_2  Golgi-dynamics membrane-trafficking
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.4   0.00014      0.61      24      67 ..      81     124 ..      66     156 .. 0.81
   2 ?   -0.9   0.1      0.49   2.2e+03      35      65 ..     352     382 ..     345     415 .. 0.65

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00014
      GOLD_2  24 fatdeydiGfGvyfewteatskavsvkvsesddeedeeeeeeee 67 
                 +at ++d   G++  w + ++++   +  + d+++de ee+eee
  EEA20724.1  81 LATGSFDATVGIWRRWDDYNNNENHEHAHDHDHDHDEGEEDEEE 124
                 69************************999999988887777644 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.49
      GOLD_2  35 vyfewteatskavsvkvsesddeedeeeeee 65 
                 vy e+  ++s +   +  e d+ ++ e+++ 
  EEA20724.1 352 VYAEFFVPSSPSSETEAKEGDEMDTSEDTKF 382
                 6777777777777777777666554444332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (439 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       471  (0.0262703); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 3144.11
//
Query:       EEA20725.1  [L=176]
Description: cAMP-regulated phosphoprotein family protein Igo1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    7.7e-29   99.7   0.0    1.3e-28   98.9   0.0    1.4  1  Endosulfine  cAMP-regulated phosphoprotein/endosulfine conser


Domain annotation for each model (and alignments):
>> Endosulfine  cAMP-regulated phosphoprotein/endosulfine conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.9   0.0   7.5e-33   1.3e-28       1      77 [.      17      92 ..      17      95 .. 0.92

  Alignments for each domain:
  == domain 1  score: 98.9 bits;  conditional E-value: 7.5e-33
  Endosulfine  1 dlsklspeelklyklyGkLPtkkdllskklqeRkYFDSgDYAlskagvaksqkaktglgskhPspertpeikqrssa 77
                 d+s+lsp+e++l +lyGk+Ptkkdll++kl+eRkYFDSgDYAlskag+a+ +   t++gs+hP pe++p++   s++
   EEA20725.1 17 DISSLSPDEQRLLRLYGKVPTKKDLLQNKLKERKYFDSGDYALSKAGKAS-DVGVTSIGSRHPVPENIPHLTATSPT 92
                 789********************************************965.56669**************9877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (176 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       436  (0.0243181); expected 358.6 (0.02)
Passed bias filter:                      247  (0.0137766); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.22s 00:00:00.61 Elapsed: 00:00:00.38
# Mc/sec: 1384.68
//
Query:       EEA20726.1  [L=205]
Description: DUF431 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.6e-75  251.1   0.0    7.5e-75  250.9   0.0    1.0  1  RNA_Me_trans  Predicted SAM-dependent RNA methyltransferase


Domain annotation for each model (and alignments):
>> RNA_Me_trans  Predicted SAM-dependent RNA methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  250.9   0.0   4.2e-79   7.5e-75       2     199 ..      12     199 ..      11     200 .. 0.97

  Alignments for each domain:
  == domain 1  score: 250.9 bits;  conditional E-value: 4.2e-79
  RNA_Me_trans   2 yviEhleeelseWvllEYrhiakevgae..nliltslskasleslpeelkslaklelekesveellkelkevkkekvclLDpkaekelspedaeefd 96 
                   +v+Ehl++el +W++lEY++ia+e++++  +++lts+++ +l+ +p++l+++++l+le++svee+++++    k++vclLDp+ae+elsp+d+++fd
    EEA20726.1  12 FVVEHLDPELGPWSALEYACIARESKESgtQFLLTSVPE-ELQ-MPDHLARMEELKLERRSVEEIFADR----KSRVCLLDPAAETELSPADGDDFD 102
                   8************************999656********.677.9***********************7....89********************** PP

  RNA_Me_trans  97 vflfGGIlGddpprdRTselrkkgfegRrLGpvqmttDtAvrvtklvvedkvkleeieyvdepelkfnkkesvempfrYvkdeegkpllpegmlell 193
                   vflfGGIl      dRTselr+kg++gRrLGpvqmttDtAvrvt++v  d+++l++i+yvd+pel++n++es+empfrYv d++gkp++p+gm+el+
    EEA20726.1 103 VFLFGGIL------DRTSELRRKGYAGRRLGPVQMTTDTAVRVTRMVSLDRIPLDKIPYVDNPELRINDHESTEMPFRYVRDSHGKPIMPDGMVELI 193
                   ********......*********************************************************************************** PP

  RNA_Me_trans 194 kkdlek 199
                   kkd++k
    EEA20726.1 194 KKDADK 199
                   ***997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (205 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       318  (0.0177366); expected 358.6 (0.02)
Passed bias filter:                      302  (0.0168442); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.42
# Mc/sec: 1479.15
//
Query:       EEA20727.1  [L=626]
Description: pheromone processing carboxypeptidase KexA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   2.1e-118  396.4   0.0   2.5e-118  396.1   0.0    1.1  1  Peptidase_S10  Serine carboxypeptidase


Domain annotation for each model (and alignments):
>> Peptidase_S10  Serine carboxypeptidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  396.1   0.0  1.4e-122  2.5e-118       4     418 ..      33     451 ..      30     452 .. 0.93

  Alignments for each domain:
  == domain 1  score: 396.1 bits;  conditional E-value: 1.4e-122
                    SST-SSEEEEEEEECSTTTTEEEEEEEEE-SSGTTTS-EEEEE--TTTB-THHHHHHTTSSEEEETTTTSEEEE-TT-GGGCSEEEEE--STTSTT CS
  Peptidase_S10   4 eetvnfkqysGYldveeeedkslFYwfveseknpeedplvlWLnGGPGCsSldGlleElGPfrvnkdstkkleenpysWnkvanvlfldqPvGvGF 99 
                     + +  k+++G+++v++e++ +lF+w +++++  +++  +lWLnGGPGCsS+dG+l+E+GP+rv+  ++++l +n+ sW++ an+lf+dqPvG+GF
     EEA20727.1  33 PDGPLLKMHAGHVEVDAETNGHLFFWHFQNRHIANRQRTILWLNGGPGCSSMDGALMEIGPYRVK--DDHTLIYNNGSWDEFANLLFVDQPVGTGF 126
                    445678***********************************************************..459************************** PP

                    -EETTSSGS--SHHHHHHHHHHHHHHHHHHSTCGTTSEEEEEEETTHHHHHHHHHHHHHTHCCH--S..STSEEEEEEEESE-SBHHHHHCCHHHH CS
  Peptidase_S10 100 SysntksdvktddeevaedlyefLkkffekfpeyksrdfyitGESYaGhyvPalakeilkknkkekk..kkinLkGlligNglideaeqvnsyvef 193
                    Sy nt+s   +d ++va+++++fL+k+f+ fpey+s+d+yi+GESYaG+y+P++a++i+++nk+ ++  ++  +kGlligNg+i++ +q+++ +++
     EEA20727.1 127 SYVNTNSY-LHDLDHVAAHMITFLEKWFAMFPEYESDDLYIAGESYAGQYIPHIARAIVERNKNIQRnqQHWPIKGLLIGNGWISPRDQYPANLQY 221
                    *****885.9*****************************************************98877799************************* PP

                    HHHTTSSHH.....HHHHHHHHHHEET.....HHHHHHHHHHHHHHHHHHHHHHHHHCHCEETTETTSEETTSSEEHHHCTTCCCCTTTTTCHHHH CS
  Peptidase_S10 194 ayehglise.....eeyeslkkacekk.....eeleqesekcanllekaskvavekenkglnvynileeccklkaelkksstdaqggedpydesyv 279
                    ay +g+++e     +e++ ++k+c+++     +    ++ +c++ l+k+   + +++ +++nvy+i+ ++             ++g+ +p d +++
     EEA20727.1 222 AYAEGIVKEgtaiaNELDGIEKSCDEQlnapgAGDLVDIRQCESILNKLLDLTRTSDDQCINVYDIRLKD------------ATCGNAWPPDLDQM 305
                    *****9996333336889999***99999999555567899999999999988888999***********............79************ PP

                    HHHHTSHHHHHHTT--.TTSSS--SB-HHH.HHHCTCCC-SBCHHHHHHHHHTT-EEEEEEETT-STT-HHHHHHHHHHTECTTECCSCCCEEEE. CS
  Peptidase_S10 280 ekylnkkeVrkalhvn.asvkkweecndsv.feqleddisksveeileellesglrvliynGdvDlicnvlgteawikklelsgkkefrpwevsp. 372
                    ++yl +++V  al+++  + + w+ecn++v  ++   +   +++++l+ l+esg++vl+++Gd Dlicn lgte++i+++++sg ++f++      
     EEA20727.1 306 TDYLRRADVGAALNLDnGKANGWTECNNQVtANFRMGHNGVPSIQLLPGLIESGVKVLLFSGDRDLICNHLGTESLIHNMKWSGGTGFETKPGVWa 401
                    ****************99999*********966666677779**********************************************99877446 PP

                    ....TTTCESEEEEEEEETTEEEEEETT--SSHHHHSHHHHHHHHHHHHT CS
  Peptidase_S10 373 ....kkengqvaGyvkeyenltfltvkgaGHmvPedkpeealqllerfis 418
                        ++ +g+ aGy+++ +nlt++  ++a+HmvP+d p+++ ++++rfi+
     EEA20727.1 402 prrgWTFEGEAAGYYQQARNLTYVLFYNASHMVPYDFPRRTRDMVDRFIN 451
                    7889********************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (626 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       497  (0.0277205); expected 358.6 (0.02)
Passed bias filter:                      448  (0.0249875); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.64u 0.26s 00:00:00.90 Elapsed: 00:00:00.44
# Mc/sec: 4267.25
//
Query:       EEA20728.1  [L=450]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   5.3e-155  516.5  10.4   6.1e-155  516.3  10.4    1.0  1  ICE2      ICE2


Domain annotation for each model (and alignments):
>> ICE2  ICE2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  516.3  10.4  3.4e-159  6.1e-155       1     405 [.       5     434 ..       5     435 .. 0.93

  Alignments for each domain:
  == domain 1  score: 516.3 bits;  conditional E-value: 3.4e-159
        ICE2   1 rvllstlyLllvvltiPlafdvGGlecGLafsltlfllYfvlttlkllarrssrlr.llasllyylqhlvipsLLilfLsrfseda.......skveet 91 
                 rv++s++yL+ +vl+iPlafdvGG++cGLa+sl+l+++Yf+++ lkl++++ssr+r ll+ l+  +q+l++p+LLi++L+ fs+d+       +     
  EEA20728.1   5 RVFSSATYLTAIVLSIPLAFDVGGKTCGLAYSLSLASFYFLFSLLKLATPDSSRFRrLLVILVGSTQWLIVPALLIWSLNLFSVDSknrsdanR----W 99 
                 799**************************************************99978899999*********************655533442....3 PP

        ICE2  92 llev...............kslseyl.......eklvvkpWkklLsnstpvftllEGfcslLvIQaigqitrwlvnrkrsdswlilllvlsgsvitsal 168
                 + ++               + +s+++       e++++++W+k+L++s+p+f+l+EGfcslLvIQa+gqitrwlvnr+  d+w+i+llv+s+s+i+s++
  EEA20728.1 100 VDNYtspssrvkdvdngvwNGISTWIfgpgglvESFAIGSWDKVLRWSSPFFQLVEGFCSLLVIQAAGQITRWLVNRSGGDTWMISLLVVSASIISSSV 198
                 333355567777888888756667778999999****************************************************************** PP

        ICE2 169 YfLyriyvfpeisvvdasllGvtltlvvflglyGivsgkGsviEsSLlfaYivlciYeifpdlsesateellellkettqneqkelpklppiilasisk 267
                 YfL+r+++fpeis+vda+l+Gv++t++v+l+++Gi+sg+G+++EsSLlfaYivlc+Y+if+d+++s +      ++++  ++ +++p+lppii+as+s+
  EEA20728.1 199 YFLWRVLQFPEISNVDAALIGVAITSAVILCAWGIGSGRGNAVESSLLFAYIVLCVYQIFTDYQPSVP------VEQAPPAQAADFPPLPPIIMASYST 291
                 ******************************************************************95......5578899999*************** PP

        ICE2 268 llkslssslpsslkeileflkaaietitpsvlisLayRilvfYaatrIiPalresgaralsq.peledsekaskilkllylyspciliavYthLllqys 365
                 l++ ls  lps+l+++++++ aa++++tps+li LayR++vfYa+trIiPa+resgaralsq ++l+d++ a+k+l+ll+++sp+il+avYt+Ll+q++
  EEA20728.1 292 LINLLSL-LPSILHAAFNVIAAAFSAVTPSILITLAYRLFVFYASTRIIPAVRESGARALSQeASLDDDDGANKLLGLLSWFSPSILVAVYTSLLMQHF 389
                 ******9.******************************************************99*********************************** PP

        ICE2 366 gelkkelklwglesivveswk........fwnWvnifltlllYavELi 405
                 +  +      g+     ++w         fw+W+n+++t++lYa+EL+
  EEA20728.1 390 AANSPGAA-GGV--AAGQWWLsqgdvgsnFWRWINLACTMALYAFELW 434
                 *9988853.333..346667688888999******************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (450 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       466  (0.0259914); expected 358.6 (0.02)
Passed bias filter:                      211  (0.0117686); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.24s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 3151.01
//
Query:       EEA20729.1  [L=555]
Description: nuclear pore complex protein (SonA), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.9e-17   62.7   1.3     0.0051   17.6   0.0    5.5  5  WD40         WD domain, G-beta repeat
    4.1e-06   26.4   1.2    4.1e-06   26.4   1.2    2.7  3  Yae1_N       Essential protein Yae1, N terminal
    5.6e-05   23.4   0.0       0.64   10.4   0.0    5.0  7  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
     0.0052   15.8   0.1      0.029   13.3   0.0    2.2  3  Ge1_WD40     WD40 region of Ge1, enhancer of mRNA-decapping p
  ------ inclusion threshold ------
      0.059   12.7   0.0        0.1   11.9   0.0    1.3  1  WD40_like    WD40-like domain
      0.092   11.4   0.0       0.29    9.7   0.0    1.7  2  Nup160       Nucleoporin Nup120/160
       0.14   12.5   0.0       0.55   10.6   0.0    1.9  2  FliO         Flagellar biosynthesis protein, FliO


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   5.2e-06     0.013      12      37 ..      37      62 ..      29      63 .. 0.91
   2 !    9.2   0.0   0.00089       2.3      10      36 ..      78     105 ..      70     107 .. 0.80
   3 !   17.6   0.0     2e-06    0.0051       9      38 .]     120     155 ..     113     155 .. 0.89
   4 ?   -0.7   0.0       1.2   3.2e+03      21      36 ..     177     192 ..     160     194 .. 0.76
   5 !   12.8   0.3   6.5e-05      0.17      12      38 .]     264     294 ..     246     294 .. 0.71

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 5.2e-06
                SEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40 12 svtslafspdgawlasGsdDgtvriW 37
                s+++lafsp ++ la +s+D++vri+
  EEA20729.1 37 SISDLAFSPVSNHLAVASWDKKVRIY 62
                599**********************8 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00089
                 S.SSEEEEEEETTSSEEEEE.ETTSEEEE CS
        WD40  10 H.ssvtslafspdgawlasG.sdDgtvri 36 
                 H  +v  +++spdg+ ++ G + D+  r+
  EEA20729.1  78 HeAPVLNCCWSPDGTKVV-GvGADKAARL 105
                 877898888*******98.6566998775 PP

  == domain 3  score: 17.6 bits;  conditional E-value: 2e-06
                 SS.SSEEEEE.....EETTSSEEEEEETTSEEEEEE CS
        WD40   9 GH.ssvtsla.....fspdgawlasGsdDgtvriWd 38 
                 +H  +++++      +++++++l++Gs+D++v+ Wd
  EEA20729.1 120 AHdAPIRCCEmipnpTNSSQPLLITGSWDKKVKYWD 155
                 79777*99*9999999999999*************9 PP

  == domain 4  score: -0.7 bits;  conditional E-value: 1.2
                 TSSEEEEEETTSEEEE CS
        WD40  21 dgawlasGsdDgtvri 36 
                  +++l+ G+ D+ + i
  EEA20729.1 177 KNKLLVIGTADRYINI 192
                 5566889*99**9988 PP

  == domain 5  score: 12.8 bits;  conditional E-value: 6.5e-05
                 S....EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  12 s....vtslafspdgawlasGsdDgtvriWd 38 
                 s    v++++f+p +  +++++ Dgt ++Wd
  EEA20729.1 264 SniysVNAISFHPVHGTFSTAGSDGTFHFWD 294
                 05455899999999999985544*******9 PP

>> Yae1_N  Essential protein Yae1, N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.3      0.74   1.9e+03       3      11 ..      66      74 ..      66      75 .. 0.84
   2 ?   -0.3   0.0      0.34   8.7e+02      29      39 .]     224     234 ..     223     234 .. 0.88
   3 !   26.4   1.2   1.6e-09   4.1e-06       1      39 []     389     427 ..     389     427 .. 0.98

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.74
      Yae1_N  3 reGiaeGke 11
                ++G++eGk+
  EEA20729.1 66 EQGQSEGKA 74
                699****96 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.34
      Yae1_N  29 GlelGqilGvl 39 
                 G+++G i+G++
  EEA20729.1 224 GFAVGSIEGRC 234
                 8999***9986 PP

  == domain 3  score: 26.4 bits;  conditional E-value: 1.6e-09
      Yae1_N   1 GYreGiaeGkeqglqeGfdeGyqeGaqlGlelGqilGvl 39 
                 GY+ G+ +G ++g+ eG  +  ++ +++ l+lG+++G++
  EEA20729.1 389 GYDLGVIDGARAGYTEGSVFAVEKSFEKLLQLGRLYGRA 427
                 9************************************96 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.9   0.0    0.0007       1.8      38      69 ..      35      66 ..      26      71 .. 0.89
   2 !   10.4   0.0   0.00025      0.64       2      70 ..      42     111 ..      41     130 .. 0.80
   3 ?   -1.4   0.0       1.2     3e+03      52      86 ..     141     173 ..     137     179 .. 0.82
   4 ?    2.5   0.0     0.071   1.8e+02      49      72 ..     177     200 ..     163     219 .. 0.82
   5 ?    2.2   0.0     0.089   2.3e+02      50      72 ..     178     200 ..     177     275 .. 0.73
   6 ?   -1.1   0.0      0.96   2.5e+03      40      76 ..     268     304 ..     250     319 .. 0.81
   7 ?   -1.6   0.0       1.3   3.3e+03      36      60 ..     306     330 ..     293     351 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0007
  ANAPC4_WD40 38 dsevrsLaWkpdgklLavaysdgevrlldaes 69
                 + ++++La++p  + Lava  d +vr++++++
   EEA20729.1 35 EDSISDLAFSPVSNHLAVASWDKKVRIYEINE 66
                 6789************************9875 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00025
  ANAPC4_WD40   2 swcptmDLiAlatedgellvfRlngqrvwtl.eedkedsevrsLaWkpdgklLavaysdgevrlldaesg 70 
                  +++p  + +A+a+ d++++++ +n q   ++ +  +++  v + +W+pdg+  + + +d + rlld    
   EEA20729.1  42 AFSPVSNHLAVASWDKKVRIYEINEQGQSEGkALFEHEAPVLNCCWSPDGTKVVGVGADKAARLLDLGAN 111
                  688999999****************999988545688999**********99999999999999997543 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 1.2
  ANAPC4_WD40  52 lLavaysdgevrlldaesgkvvhslsvksekavtc 86 
                  lL  +  d +v+  d  +++ + ++++++   v +
   EEA20729.1 141 LLITGSWDKKVKYWDLRQQTPIAQVECQER--VYT 173
                  678888899999999999999999999977..555 PP

  == domain 4  score: 2.5 bits;  conditional E-value: 0.071
  ANAPC4_WD40  49 dgklLavaysdgevrlldaesgkv 72 
                  ++klL+++++d  +++++  + + 
   EEA20729.1 177 KNKLLVIGTADRYINIINLDNPTS 200
                  689**************9987655 PP

  == domain 5  score: 2.2 bits;  conditional E-value: 0.089
  ANAPC4_WD40  50 gklLavaysdgevrlldaesgkv 72 
                  +klL+++++d  +++++  + + 
   EEA20729.1 178 NKLLVIGTADRYINIINLDNPTS 200
                  57777777777777777766544 PP

  == domain 6  score: -1.1 bits;  conditional E-value: 0.96
  ANAPC4_WD40  40 evrsLaWkpdgklLavaysdgevrlldaesgkvvhsl 76 
                  +v++++++p    +  a sdg+ ++ d   ++ ++ +
   EEA20729.1 268 SVNAISFHPVHGTFSTAGSDGTFHFWDKDAKHRLKGY 304
                  689999999999999999***9999998877766655 PP

  == domain 7  score: -1.6 bits;  conditional E-value: 1.3
  ANAPC4_WD40  36 kedsevrsLaWkpdgklLavaysdg 60 
                  + ++++ +  ++ dg+++a a+s  
   EEA20729.1 306 NVGGTIPCTTFNRDGSIFAYAVSYD 330
                  6678888899999999999998755 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.3   0.0   1.1e-05     0.029     166     229 ..      14      77 ..       5      81 .. 0.83
   2 ?    0.3   0.0       0.1   2.7e+02     177     208 ..      69     100 ..      64     106 .. 0.78
   3 ?   -2.3   0.0      0.67   1.7e+03     190     214 ..     269     293 ..     219     300 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.1e-05
    Ge1_WD40 166 kygsgelsveeieegllkieehsliveaafspdGtalatasedGevkffqvyledeeeprCLhe 229
                     ++++ +  +++ l+   +  i++ afsp    la+as d +v+ + ++ ++++e + L e
  EEA20729.1  14 TTAATNTTGDISKDVALNSPPEDSISDLAFSPVSNHLAVASWDKKVRIYEINEQGQSEGKALFE 77 
                 555566677777778888888889********************************99999976 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.1
    Ge1_WD40 177 ieegllkieehsliveaafspdGtalatased 208
                 ++eg   +e+++ + +  +spdGt +    +d
  EEA20729.1  69 QSEGKALFEHEAPVLNCCWSPDGTKVVGVGAD 100
                 5567777899999***********98766665 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 0.67
    Ge1_WD40 190 iveaafspdGtalatasedGevkff 214
                 +   +f p   + +ta +dG+ +f+
  EEA20729.1 269 VNAISFHPVHGTFSTAGSDGTFHFW 293
                 4445666766778888888888887 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0     4e-05       0.1      12     112 ..      91     197 ..      81     212 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 4e-05
   WD40_like  12 gslilyGgkddkctvlkleslesvsi.vesfedSvifvkllddd......lilvvtlDGtillslleneeevenekieedistvkviddklliGtnkGs 103
                 g+ ++  g d+ +++l+l  + +  + v+  +  +  ++++ +       l++ ++ D ++   +l+++  + + + +e + t++v ++ l+iGt    
  EEA20729.1  91 GTKVVGVGADKAARLLDLGANATTPVqVAAHDAPIRCCEMIPNPtnssqpLLITGSWDKKVKYWDLRQQTPIAQVECQERVYTMDVKNKLLVIGTADRY 189
                 55555556677777777766655544144555567778888765555666889999*****99*********************************999 PP

   WD40_like 104 iyvfskdlq 112
                 i + + d +
  EEA20729.1 190 INIINLD-N 197
                 9999988.4 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       0.3   7.7e+02     221     249 ..      41      66 ..      19      89 .. 0.78
   2 ?    9.7   0.0   0.00011      0.29     226     314 ..     135     223 ..     112     251 .. 0.73

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.3
                 EET.....TTTEEEEEETT-EEEEEETTT CS
      Nup160 221 vavavveigqtylfalsrdgkLrvWnllt 249
                 +a++ v   +++l+++s d+k+r+  ++ 
  EEA20729.1  41 LAFSPV---SNHLAVASWDKKVRIYEINE 66 
                 444444...69************998765 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.00011
                 ...TTTEEEEEETT-EEEEEETTTTEEEEEEE--.-SSSTTS--SSEESEEESSSSEEEE..........E--GGG-EEEEEEEEEEE- CS
      Nup160 226 veigqtylfalsrdgkLrvWnlltgkclatidllrdeeaqdessskstldpaesslirvsdggqsylvvtyspssggefkvwkvkkedt 314
                 +++ q +l + s d+k++ W+l+ ++++a+ +++  +++ d + + + +++a+ ++ ++  ++ +++  t+  + + ++ v+  ++++t
  EEA20729.1 135 TNSSQPLLITGSWDKKVKYWDLRQQTPIAQVECQERVYTMDVKNKLLVIGTADRYINIINLDNPTSFYKTMQSPLKWQTRVVSCFADAT 223
                 455788899999**********************5577777777778889998888888755555555555555566666666555555 PP

>> FliO  Flagellar biosynthesis protein, FliO
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00021      0.55      29      57 ..     165     193 ..     161     224 .. 0.83
   2 ?   -2.3   0.0       2.2   5.5e+03      49      74 ..     338     365 ..     337     385 .. 0.64

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00021
        FliO  29 lgpkervvlVevgeellllGvtpgsislL 57 
                 +  +erv+  +v+++ll++G ++  i+++
  EEA20729.1 165 VECQERVYTMDVKNKLLVIGTADRYINII 193
                 5668********************99998 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 2.2
        FliO  49 vtpgsis..lLheltkaeapeppsaeea 74 
                  tp++++  +Lh +t++e +  p+a ++
  EEA20729.1 338 NTPQTVNkvMLHPVTQEEVKPRPNARKP 365
                 5777775225788877766666554443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (555 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       389  (0.0216967); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.61u 0.30s 00:00:00.90 Elapsed: 00:00:00.48
# Mc/sec: 3479.51
//
Query:       EEA20730.1  [L=184]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
      0.052   13.6   0.2       0.55   10.3   0.0    2.4  2  IPU_b_solenoid  Isopullulanase beta-solenoid repeat
       0.09   12.8   0.0       0.17   11.9   0.0    1.4  1  HHH_4           Helix-hairpin-helix containing domain


Domain annotation for each model (and alignments):
>> IPU_b_solenoid  Isopullulanase beta-solenoid repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.1     0.081   7.2e+02       1       7 [.      71      77 ..      71      79 .. 0.95
   2 ?   10.3   0.0   6.2e-05      0.55      15      33 .]     110     129 ..     109     129 .. 0.92

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.081
  IPU_b_solenoid  1 WKtntAP 7 
                    WK nt P
      EEA20730.1 71 WKLNTSP 77
                    *****99 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 6.2e-05
  IPU_b_solenoid  15 sRnltNitV.dhVdvIHsrY 33 
                      Rnl+ +t+ d+ d IH++Y
      EEA20730.1 110 ARNLKGVTIkDALDAIHKQY 129
                     7********889******99 PP

>> HHH_4  Helix-hairpin-helix containing domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   1.9e-05      0.17      22      45 ..     122     144 ..     111     151 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 1.9e-05
       HHH_4  22 aekiykkygeealeilkenPYrli 45 
                 + +i+k+y+++a + l enPY l+
  EEA20730.1 122 LDAIHKQYKKKADDELGENPY-LA 144
                 568******************.54 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (184 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1359  (0.075799); expected 358.6 (0.02)
Passed bias filter:                      456  (0.0254337); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.25s 00:00:00.67 Elapsed: 00:00:00.40
# Mc/sec: 1373.41
//
Query:       EEA20731.1  [L=932]
Description: hydrolase, alpha/beta fold family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.6e-09   37.8   0.2    8.1e-09   35.5   0.0    2.3  3  Abhydrolase_1  alpha/beta hydrolase fold
    4.3e-08   34.0   0.4      5e-07   30.5   0.4    2.5  1  Abhydrolase_6  Alpha/beta hydrolase family
    2.7e-05   23.5   0.0    0.00023   20.5   0.0    2.3  3  Hydrolase_4    Serine aminopeptidase, S33
  ------ inclusion threshold ------
       0.39   10.5   5.1        0.8    9.5   5.1    1.4  1  DUF724         Protein of unknown function (DUF724)


Domain annotation for each model (and alignments):
>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   0.1         2     9e+03     152     187 ..     325     360 ..     322     392 .. 0.63
   2 !   35.5   0.0   1.8e-12   8.1e-09      23     110 ..     566     653 ..     547     701 .. 0.88
   3 ?   -2.1   0.0      0.52   2.3e+03     206     250 ..     835     877 ..     763     880 .. 0.75

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 2
                    HHHHHHHHHHHHHCHHHCCHHHHHHHCHHHHHHHHH CS
  Abhydrolase_1 152 eqrhrlvdalkfpdkskrfpssgsdnasslatgalk 187
                     +rh++ ++l+ ++  +r+p+++s++ +  +++++k
     EEA20731.1 325 SLRHSINNKLNRKSRQSRPPEQRSTTGKERSHVESK 360
                    568888888877777777777777777666655433 PP

  == domain 2  score: 35.5 bits;  conditional E-value: 1.8e-12
                    HHHHHT.TSEEEEEEETTSTTSSSTTTGB.CHHSHHHHHHHHHHHHHHCTTSSEEEEEETHHHHHHHHHHHHHGGGEEEEEEESE..CSSC CS
  Abhydrolase_1  23 paLakd.gfdvillDlrGvgySspapacinddygtasvaddldrildalgddkltlvGhSmGGmialayaaeyperVkalvllga..idpa 110
                    + La++ + ++++lD +Gvg+S+p+ +    + +  +  dd+  ++++l++ k+ +++hS G   ala a++ p+++++ + l a  i+p+
     EEA20731.1 566 DELARTlKLRLVTLDRPGVGESDPSGE---GEGTPLTWPDDVAIVCNHLKITKFSILAHSAGAIYALATALRIPQHIRGRIHLLApwIPPS 653
                    467777799*****************9...899999******************************************8666666254444 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 0.52
                    CTHHHHSEEEEEEETTCSSSCHHHHHHHHHCHTSEEEEEEETCSS CS
  Abhydrolase_1 206 elknvlaptlvisgtsDplvppkaledlaqllpkkrlvvisdagH 250
                       +++  +++ +gt+D  vp ++ + l +  ++ +++v++++gH
     EEA20731.1 835 V--DINREVVIHHGTKDTRVPVDNVRWLGKTMRRCEVRVLEGEGH 877
                    3..555589999999999999988888888866668888888888 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.5   0.4   1.1e-10     5e-07       6     126 ..     554     687 ..     548     889 .. 0.59

  Alignments for each domain:
  == domain 1  score: 30.5 bits;  conditional E-value: 1.1e-10
                    -GC.....GC.HHHHHHHHCCTCEEEEE--TTSTS-......GGCS--HHHCHHHHHHHCCTT..TTSEEEEEETCHHHHHHHHHHCC.......E CS
  Abhydrolase_6   6 GagssassWl.vapLaallaagvhvlapDlpGhGrs......dpppldledladlaalldelaagggpvvlvGHSlGGalalaaapla.....lvv 89 
                    G g++++  + +++La+ l  +   +++D+pG G+s      ++ pl++   +d+a + ++l+    ++ +++HS G+++ala    a      ++
     EEA20731.1 554 GMGLTRYLMAfYDELARTLKLRL--VTLDRPGVGESdpsgegEGTPLTW--PDDVAIVCNHLK--ITKFSILAHSAGAIYALA---TAlripqHIR 640
                    66665555534889999999999..9********553455556677999..578899999997..9999**************...6666687444 PP

                    E..EEES-..........----TTTS----TTHHHHHHTT-CCCCHC CS
  Abhydrolase_6  90 g..vlldp..pp......talpagllaaalelllallallrllawls 126
                    g   ll+p  pp      ++   +l++ a+++ ++ l++l+++ + +
     EEA20731.1 641 GriHLLAPwiPPsqmtnlGTHKEPLPNNAVPYSQRILRALPTPILKV 687
                    47555555553344433322222224444444444444555433332 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.1      0.86   3.8e+03     160     210 ..     391     449 ..     357     469 .. 0.60
   2 !   20.5   0.0   5.2e-08   0.00023      19     118 ..     564     664 ..     544     752 .. 0.77
   3 ?   -0.6   0.0      0.14   6.5e+02     190     235 ..     837     880 ..     820     881 .. 0.83

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 0.86
  Hydrolase_4 160 adplv.hgkitvrlllelldamkrleeraakit.......lPllllhGeaDkvvdpeas 210
                  + + v  g+++++++++  ++++ + ++ + ++       +   l+h+e D+  + ++s
   EEA20731.1 391 KAQEVpAGRTSIETFTSRAKTTQPAAAEPTPAQlsqedalISRYLIHAETDPFEESAPS 449
                  44444466666666666666665555554444444555555667788888877777666 PP

  == domain 2  score: 20.5 bits;  conditional E-value: 5.2e-08
  Hydrolase_4  19 ryaelaeaLaaqGfavyalDhrGhGrsegkrghvpsfddyvdDlaafvekvkeehpelplfllGhSmGGliallyllrypdkva.glilsaPalkika 115
                   y+ela+ L       ++lD  G G+s++         ++ dD+a +++++k     +++ +l+hS G++ al+ +lr p++++ ++ l aP++ + +
   EEA20731.1 564 FYDELARTLK---LRLVTLDRPGVGESDPSGEGEGTPLTWPDDVAIVCNHLK----ITKFSILAHSAGAIYALATALRIPQHIRgRIHLLAPWIPPSQ 654
                  5666666665...56899*********96666667777899******99999....8899************************77779****98776 PP

  Hydrolase_4 116 kl.......k 118
                  ++       +
   EEA20731.1 655 MTnlgthkeP 664
                  5444444330 PP

  == domain 3  score: -0.6 bits;  conditional E-value: 0.14
  Hydrolase_4 190 itlPllllhGeaDkvvdpeasrelyerlgskdktlklypglyHell 235
                  i+  + + hG++D+ v+ ++ r l ++++  ++++++ +g  H l+
   EEA20731.1 837 INREVVIHHGTKDTRVPVDNVRWLGKTMR--RCEVRVLEGEGHGLM 880
                  55567899****************99999..699999999999876 PP

>> DUF724  Protein of unknown function (DUF724)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   5.1   0.00018       0.8      89     160 ..     325     395 ..     324     417 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00018
      DUF724  89 alqsrlnkLlslkdeqtklleerkklekkieeeesekrkleeeidelekkilelerqlallkekkeaadkei 160
                 +l++ +n+ l+ k++q++  e+r+   k+ ++ es+ +++ +  +++ k+i+e+++q++++k++  a+++e+
  EEA20731.1 325 SLRHSINNKLNRKSRQSRPPEQRSTTGKERSHVESKTSEARAATEQTTKRIQEVKEQQMRIKNEL-AKAQEV 395
                 57899*****************************************************9999433.444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (932 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1403  (0.0782531); expected 358.6 (0.02)
Passed bias filter:                      591  (0.0329634); expected 358.6 (0.02)
Passed Vit filter:                        72  (0.00401584); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.94u 0.31s 00:00:01.25 Elapsed: 00:00:00.51
# Mc/sec: 5494.44
//
Query:       EEA20732.1  [L=413]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      3e-88  294.6   7.1    1.2e-78  263.2   0.7    2.2  2  Helo_like_N     Fungal N-terminal domain of STAND proteins
    0.00014   20.8   9.8       0.22   10.4   0.1    3.2  3  Spc7            Spc7 kinetochore protein
    0.00048   20.3   5.5      0.091   13.0   0.0    3.3  3  SesA            N-terminal domain on NACHT_NTPase and P-loop 
    0.00072   19.6   9.2        1.2    9.1   0.0    3.5  3  DUF1664         Protein of unknown function (DUF1664)
  ------ inclusion threshold ------
      0.011   15.8   2.3        2.5    8.1   0.0    3.3  3  PilJ            Type IV pili methyl-accepting chemotaxis tran
      0.012   15.8  10.2      0.042   14.0   0.0    3.8  3  RasGAP_C        RasGAP C-terminus
      0.029   14.7  10.1        0.6   10.5   0.4    3.6  3  CLZ             C-terminal leucine zipper domain of cyclic nu
       0.09   12.9  14.1        1.7    8.7   0.4    3.9  4  COG2            COG (conserved oligomeric Golgi) complex comp
        0.1   12.5  10.0       0.68    9.8   0.3    3.5  4  Apolipoprotein  Apolipoprotein A1/A4/E domain
        0.2   11.2  11.0          7    6.2   0.8    3.5  3  PI3K_P85_iSH2   Phosphatidylinositol 3-kinase regulatory subu
       0.26   11.5  10.5        3.3    7.9   0.0    3.6  4  COG5            Golgi transport complex subunit 5
        0.6   10.6   9.4        5.1    7.6   0.3    3.9  3  DASH_Dad2       DASH complex subunit Dad2
       0.71   10.4   7.2        8.3    7.0   0.1    3.5  3  NPV_P10         Nucleopolyhedrovirus P10 protein
        1.4    9.6  11.3        9.7    6.9   0.4    4.0  3  SlyX            SlyX
        1.7    8.8   5.4          1    9.5   0.4    3.0  3  DUF4363         Domain of unknown function (DUF4363)
        3.5    7.7   8.3        1.1    9.3   0.0    3.2  3  Spore_III_AB    Stage III sporulation protein AB (spore_III_A
        3.5    8.0  12.9         22    5.4   0.7    4.0  3  KxDL            Uncharacterized conserved protein
        3.5    8.3  12.4          5    7.8   1.5    3.7  4  ING             Inhibitor of growth proteins N-terminal histo
        4.8    7.3  13.3          6    7.0   0.3    4.5  4  DUF2205         Short coiled-coil protein
        7.7    6.8  14.3        5.6    7.2   0.0    4.0  3  Seryl_tRNA_N    Seryl-tRNA synthetase N-terminal domain
        8.7    7.1  11.5        0.9   10.3   0.3    3.7  3  Plk4_PB2        Polo-like Kinase 4 Polo Box 2
        9.7    6.6  16.9        1.2    9.5   3.0    3.7  4  YlqD            YlqD protein


Domain annotation for each model (and alignments):
>> Helo_like_N  Fungal N-terminal domain of STAND proteins
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  263.2   0.7   1.5e-81   1.2e-78       2     209 .]       3     209 ..       2     209 .. 0.99
   2 !   34.8   0.9   1.3e-11     1e-08     136     209 .]     238     309 ..     235     309 .. 0.90

  Alignments for each domain:
  == domain 1  score: 263.2 bits;  conditional E-value: 1.5e-81
  Helo_like_N   2 dplsiasgvlalvtfalqssksLyetvksfrsrdktvreLkeeleaLeevLesLeevavaeeeselalLklpllrCgkaCkefeqvikkcskkssksr 99 
                  dpls++++++al+ fa+q+sksLy++v+sf+s++++vreL+ee+e+L++vLe+L++  + e +++l++Lklpl +C k+C+efe+vi+kc+++s+++r
   EEA20732.1   3 DPLSVSASLVALTGFAFQASKSLYQAVDSFKSSKRAVRELREEVESLNGVLENLSQ-MAVEYDAQLTSLKLPLVQCAKTCEEFERVISKCVGHSDGQR 99 
                  9*******************************************************.6689************************************* PP

  Helo_like_N 100 tsfrDwakleymggdindfketlagYKsTisiaLgdinlrkskvtaevleeykeliedttsdLeehLedideklealtekseeaseedeaelqrlkeE 197
                  tsfrDwa+l+y gg ++++k+tlagYKsTisia+g +++r+  vta+vl++y+++ie++tsdL+ehL+ id+++++l+++s++ ++++  e++++ eE
   EEA20732.1 100 TSFRDWAQLQYRGGGMENLKTTLAGYKSTISIAIGGATFRQVVVTANVLDDYQKMIEEATSDLQEHLQLIDKRMQSLMQNSASIQANRPPEVEEIVEE 197
                  ***********99************************************************************************************* PP

  Helo_like_N 198 resteqcleice 209
                  ++s++qcl+ic+
   EEA20732.1 198 KRSIRQCLAICT 209
                  ***********5 PP

  == domain 2  score: 34.8 bits;  conditional E-value: 1.3e-11
  Helo_like_N 136 inlrkskvtaevleeykeliedttsdLeehLedideklealtekseeaseedeaelqrlkeEresteqcleice 209
                  +++  +++t++ l  +++ +++ t++L+++L++++++l +l+e+ ++  +++ + lq++keEr+s+++cleic+
   EEA20732.1 238 ATFGAETATNDLLMGFRTRLSSNTKNLQDRLQELENRLGKLSENGDD--QQHLNLLQAMKEERDSISHCLEICT 309
                  77888999**********************************66554..577778999***************5 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.4   0.1   0.00027      0.22     201     264 ..      32      95 ..      19     104 .. 0.76
   2 !    8.3   0.5    0.0012      0.94     155     215 ..     145     205 ..     136     229 .. 0.78
   3 !    6.9   0.6     0.003       2.4     199     260 ..     248     308 ..     230     357 .. 0.44

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00027
        Spc7 201 Leelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaervleeckgws 264
                  ++ +++++el +e+e+++  l++l +   e ++++++lk    ++ +  +e erv+ +c g+s
  EEA20732.1  32 FKSSKRAVRELREEVESLNGVLENLSQMAVEYDAQLTSLKLPLVQCAKTCEEFERVISKCVGHS 95 
                 4566777788888888888888888888888888888888888888888888888888887776 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.0012
        Spc7 155 kelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaei 215
                 +++L++ ++ ++e+  +l+e+ + + +++++l + ++++++  + e+ee+ ee +++ + +
  EEA20732.1 145 ANVLDDYQKMIEEATSDLQEHLQLIDKRMQSLMQNSASIQANRPPEVEEIVEEKRSIRQCL 205
                 6788999999999999999999999999999999999999988888888877777666554 PP

  == domain 3  score: 6.9 bits;  conditional E-value: 0.003
        Spc7 199 eeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaervleec 260
                 + L  +r +l+++ ++++ + +el+++  +l e  ++ ++l +  + ++ee  +  + le c
  EEA20732.1 248 DLLMGFRTRLSSNTKNLQDRLQELENRLGKLSENGDDQQHL-NLLQAMKEERDSISHCLEIC 308
                 44444444444444444444444444444433333333332.12222222222222222222 PP

>> SesA  N-terminal domain on NACHT_NTPase and P-loop NTPases
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.0   0.0   0.00011     0.091       7      92 ..      18     100 ..      12     128 .. 0.78
   2 ?    5.4   0.3     0.025        21      22      82 ..     153     217 ..     136     228 .. 0.77
   3 ?    2.8   0.2      0.15   1.2e+02      38      86 ..     264     311 ..     246     338 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 0.00011
        SesA   7 iveaaiklydaikdikglpeaFrevgkrLplvqetLedaksqlesskldedtesaikpvlesckekatkleeifekvapapadsrl 92 
                  ++a+ +ly+a+++ k+ ++a re  ++++ +  +Le   + + + +++ ++   +k  l +c +  ++ e++  k +   + +r+
  EEA20732.1  18 AFQASKSLYQAVDSFKSSKRAVRELREEVESLNGVLENLSQMAVEYDAQLTS---LKLPLVQCAKTCEEFERVISKCVGHSDGQRT 100
                 67999*******************************9999988887777754...7888999**********99999776666554 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.025
        SesA  22 kglpeaFrevgkrLplvqetLedaksqlesskldedtesa....ikpvlesckekatkleeifek 82 
                 k + ea ++ +++L+l+ +  ++  ++  s +++   e +     k ++++c +  t+++++ e+
  EEA20732.1 153 KMIEEATSDLQEHLQLIDKRMQSLMQNSASIQANRPPEVEeiveEKRSIRQCLAICTQVSQLIEA 217
                 557789999*************9999988888888777656666677777777766666666665 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.15
        SesA  38 vqetLedaksqlesskldedtesaikpvlesckekatkleeifekvapa 86 
                 +q+ L++ +++l + +++ d+++   ++l++ ke+ ++++  +e  ++a
  EEA20732.1 264 LQDRLQELENRLGKLSENGDDQQ-HLNLLQAMKEERDSISHCLEICTEA 311
                 68889999999999999999888.6677777777666666555554333 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   0.0    0.0015       1.2      46     111 ..      21      89 ..      13      94 .. 0.78
   2 !    8.8   1.2     0.002       1.6      47     103 ..     145     205 ..     138     221 .. 0.74
   3 ?    4.8   0.5     0.033        27      37      96 ..     262     322 ..     245     347 .. 0.58

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0015
     DUF1664  46 vskqleqvseslaatk...rhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeave 111
                  sk+l q  +s ++ k   r+L +++++++  l++ ++++ e ++++t+++  l +  +  e+ +++++
  EEA20732.1  21 ASKSLYQAVDSFKSSKravRELREEVESLNGVLENLSQMAVEYDAQLTSLKLPLVQCAKTCEEFERVIS 89 
                 567777777777776633358899999999999999999999999999999999888888888888876 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.002
     DUF1664  47 skqleqvseslaatkrhLssridrvdkkldeqkeiskeike....evtevredlseigedv 103
                 ++ l++ ++ ++++  +L+++++ +dk++++ ++ s++i++    ev+e+ e+ ++i++ +
  EEA20732.1 145 ANVLDDYQKMIEEATSDLQEHLQLIDKRMQSLMQNSASIQAnrppEVEEIVEEKRSIRQCL 205
                 5679999***********************9999999998633335777766666665543 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.033
     DUF1664  37 rslsdavesvskqleqvseslaatkr.hLssridrvdkkldeqkeiskeikeevtevredl 96 
                 ++l+d ++++ ++l ++se+  ++++ +L + +++  +++ ++ ei +e ++  ++vr ++
  EEA20732.1 262 KNLQDRLQELENRLGKLSENGDDQQHlNLLQAMKEERDSISHCLEICTEASDLTATVRTNV 322
                 5666666666666666666554433225556666666666666666666555555555555 PP

>> PilJ  Type IV pili methyl-accepting chemotaxis transducer N-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.0         1   8.2e+02      40      65 ..      35      60 ..      11      90 .. 0.57
   2 ?    8.1   0.0    0.0031       2.5      40      76 ..     155     193 ..     119     223 .. 0.80
   3 ?    5.3   0.1     0.024        20      38      80 ..     255     297 ..     242     325 .. 0.77

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 1
        PilJ 40 aaearaqlretiaqfdrtlaalrlgd 65
                + +a ++lre ++ ++  l++l++ +
  EEA20732.1 35 SKRAVRELREEVESLNGVLENLSQMA 60
                34444445555544444444444433 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0031
        PilJ  40 aaearaqlretiaqfdrtlaalrlgdpapgllvpae..a 76 
                 ++ea ++l+e+++++d+++++l + +++ +   p+e  +
  EEA20732.1 155 IEEATSDLQEHLQLIDKRMQSLMQNSASIQANRPPEveE 193
                 589999999999999999999999999888888886662 PP

  == domain 3  score: 5.3 bits;  conditional E-value: 0.024
        PilJ  38 ydaaearaqlretiaqfdrtlaalrlg.dpapgllvpaeavraq 80 
                 +  +++ ++l++++++++++l  l++  d++++l   + a++++
  EEA20732.1 255 TRLSSNTKNLQDRLQELENRLGKLSENgDDQQHLNLLQ-AMKEE 297
                 56688999****************98735555555554.66665 PP

>> RasGAP_C  RasGAP C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   5.1e-05     0.042      39      90 ..      33      84 ..      25     125 .. 0.81
   2 ?    5.4   0.5     0.024        19      55      91 ..     148     184 ..     138     226 .. 0.70
   3 ?    0.1   0.1      0.99   8.1e+02      22      73 ..     328     383 ..     321     391 .. 0.65

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 5.1e-05
    RasGAP_C 39 rnkgrlrekrkeElesleetlktLseknnylesqlesYkayienvleqlkkk 90
                ++ +r+ ++ +eE+esl+ +l++Ls+    +  ql s+k  + ++ +++++ 
  EEA20732.1 33 KSSKRAVRELREEVESLNGVLENLSQMAVEYDAQLTSLKLPLVQCAKTCEEF 84
                56677788899************************************99554 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.024
    RasGAP_C  55 leetlktLseknnylesqlesYkayienvleqlkkkk 91 
                 l +  k ++e ++ l+++l+  ++ +++ ++++++ +
  EEA20732.1 148 LDDYQKMIEEATSDLQEHLQLIDKRMQSLMQNSASIQ 184
                 4455566666667777777777777777777665543 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.99
    RasGAP_C  22 srennyqellneIakdirnkgrlrekrkeEl..esleetlktLse..knnylesql 73 
                 s +n++q +++ I   i  k+    +   +   ++  et+++Ls+  k++++e+q 
  EEA20732.1 328 SADNSHQLVVSTIGDLISAKHITTGSNSVQWlgQMSDETIQKLSSdnKRAFFENQT 383
                 66788888888888878777766655555533377778888886511445666665 PP

>> CLZ  C-terminal leucine zipper domain of cyclic nucleotide-gated channels
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.1      0.17   1.4e+02      21      46 ..      34      59 ..      27      82 .. 0.70
   2 ?   10.5   0.4   0.00074       0.6      24      59 ..     150     185 ..     141     187 .. 0.89
   3 ?    5.6   0.6     0.026        21      30      54 ..     258     282 ..     253     295 .. 0.72

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.17
         CLZ 21 kagaeqkeleekverLessLeaLqtr 46
                +++   +el e ve+L++ Le+L + 
  EEA20732.1 34 SSKRAVRELREEVESLNGVLENLSQM 59
                45566678888888888888888764 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00074
         CLZ  24 aeqkeleekverLessLeaLqtrlarLlaeyessqr 59 
                 + qk +ee  + L+++L+ +++r++ L+++  s q+
  EEA20732.1 150 DYQKMIEEATSDLQEHLQLIDKRMQSLMQNSASIQA 185
                 56899************************9999886 PP

  == domain 3  score: 5.6 bits;  conditional E-value: 0.026
         CLZ  30 eekverLessLeaLqtrlarLlaey 54 
                  ++ ++L+ +L+ L++rl +L ++ 
  EEA20732.1 258 SSNTKNLQDRLQELENRLGKLSENG 282
                 4566788888888888888886554 PP

>> COG2  COG (conserved oligomeric Golgi) complex component, COG2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.4    0.0021       1.7      58     131 ..       5      86 ..       2      90 .. 0.84
   2 ?    4.0   1.4     0.059        48      64     124 ..     148     206 ..     139     219 .. 0.49
   3 ?    7.3   0.1     0.006       4.9      79     124 ..     251     296 ..     245     305 .. 0.83
   4 ?   -2.2   0.0       4.9     4e+03      80     120 ..     321     360 ..     309     372 .. 0.55

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0021
        COG2  58 vslSghLvglqeeleevesplaaarkkvesvreklsereeeveskleeakeleekr.......ellkl.llkldevveklea 131
                 +s+S++Lv l     + +++l +a++ ++s ++++ e +eeves     ++l ++         +lkl l+++++++e+ e+
  EEA20732.1   5 LSVSASLVALTGFAFQASKSLYQAVDSFKSSKRAVRELREEVESLNGVLENLSQMAveydaqlTSLKLpLVQCAKTCEEFER 86 
                 6899*******9999********************99999999987777777777776788885555448889999998886 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.059
        COG2  64 Lvglqeeleevesplaaarkkvesvreklsereeeveskl.eeakeleekrellklllklde 124
                 L ++q+ +ee +s+l++  + +++ +++l ++++ ++++   e +e+ e++   ++++++ +
  EEA20732.1 148 LDDYQKMIEEATSDLQEHLQLIDKRMQSLMQNSASIQANRpPEVEEIVEEK---RSIRQCLA 206
                 555666666666666666666666666666666555544312333332222...22222222 PP

  == domain 3  score: 7.3 bits;  conditional E-value: 0.006
        COG2  79 aaarkkvesvreklsereeeveskleeakeleekrellklllklde 124
                   +r++++s++++l++r +e+e++l + +e  + ++ l+ll+ ++e
  EEA20732.1 251 MGFRTRLSSNTKNLQDRLQELENRLGKLSENGDDQQHLNLLQAMKE 296
                 5689999******************999999999988888877765 PP

  == domain 4  score: -2.2 bits;  conditional E-value: 4.9
        COG2  80 aarkkvesvreklsereeeveskleeakeleekrellklll 120
                 ++ ++v+s+ ++ +   +++ + ++++ +++  +++++ l 
  EEA20732.1 321 NVYEEVKSADNSHQLVVSTIGDLISAK-HITTGSNSVQWLG 360
                 445666666666666666666666544.4444445555544 PP

>> Apolipoprotein  Apolipoprotein A1/A4/E domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.4      0.22   1.8e+02     154     183 ..      37      69 ..      18      76 .. 0.55
   2 ?    5.7   0.1     0.015        12      57      88 ..     148     178 ..     112     221 .. 0.56
   3 ?    9.8   0.3   0.00083      0.68      26      60 ..     252     285 ..     233     324 .. 0.85
   4 ?   -3.3   0.0       8.5     7e+03      21      36 ..     360     375 ..     358     399 .. 0.68

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.22
                     SHHHHHHHTS-T...TSHHHHHS--XXXXXXXX CS
  Apolipoprotein 154 srveelreklee...qaeelrerleanleelka 183
                     + v+elre++e     +e+l + + ++ ++l++
      EEA20732.1  37 RAVRELREEVESlngVLENLSQMAVEYDAQLTS 69 
                     344444444444444666666666666666655 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.015
                     HHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHH CS
  Apolipoprotein  57 rdevqeqlgqnleelrqrlapyteelrerlaa 88 
                     +d+ q+++++ + +l+++l+ ++++++++l +
      EEA20732.1 148 LDDYQKMIEEATSDLQEHLQ-LIDKRMQSLMQ 178
                     23333333333333333332.22222222222 PP

  == domain 3  score: 9.8 bits;  conditional E-value: 0.00083
                     HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH CS
  Apolipoprotein  26 elrdrlskeleelrarlraeleevrarlepyrdev 60 
                      +r+rls ++++l++rl +ele+   +l++  d+ 
      EEA20732.1 252 GFRTRLSSNTKNLQDRL-QELENRLGKLSENGDDQ 285
                     58999999999999999.99999999999888765 PP

  == domain 4  score: -3.3 bits;  conditional E-value: 8.5
                     HCHHHHHHHHHHHHHH CS
  Apolipoprotein  21 aplaqelrdrlskele 36 
                     +++++e++++ls + +
      EEA20732.1 360 GQMSDETIQKLSSDNK 375
                     5666666666666654 PP

>> PI3K_P85_iSH2  Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   0.1     0.015        12      88     142 ..      30      84 ..      20      91 .. 0.87
   2 ?    6.2   0.8    0.0086         7      81     125 ..     157     201 ..     136     221 .. 0.71
   3 ?    5.0   0.5      0.02        17      85     115 ..     256     286 ..     252     309 .. 0.84

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.015
  PI3K_P85_iSH2  88 enleqlksrlkelhsskekLeedlkqqkeeereleReinalkpellqLqkrkdky 142
                    ++++  k+ + el+++ e+L+  l++  +   e + ++++lk  l+q +k+ +++
     EEA20732.1  30 DSFKSSKRAVRELREEVESLNGVLENLSQMAVEYDAQLTSLKLPLVQCAKTCEEF 84 
                    5677788999********************************9999988876665 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.0086
  PI3K_P85_iSH2  81 hEieklqenleqlksrlkelhsskekLeedlkqqkeeereleRei 125
                    +  ++lqe+l+++ +r+++l +++++++ +   ++ee  e  R+i
     EEA20732.1 157 EATSDLQEHLQLIDKRMQSLMQNSASIQANRPPEVEEIVEEKRSI 201
                    334578888888888888888888888887777777766666665 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.02
  PI3K_P85_iSH2  85 klqenleqlksrlkelhsskekLeedlkqqk 115
                    +l++n ++l++rl+el++   kL+e+   q 
     EEA20732.1 256 RLSSNTKNLQDRLQELENRLGKLSENGDDQQ 286
                    7899**************9999999866655 PP

>> COG5  Golgi transport complex subunit 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   0.0    0.0041       3.3      57     117 ..      22      82 ..      13      91 .. 0.87
   2 ?    4.3   0.2     0.051        42      17      57 ..     141     181 ..     137     216 .. 0.84
   3 ?    4.6   0.6     0.043        35      29      95 ..     255     322 ..     237     353 .. 0.75
   4 ?   -2.7   0.1       7.8   6.4e+03      46      77 ..     364     396 ..     359     404 .. 0.72

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0041
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-TTHHHHHHHHHHHHHHHHHHHHHH CS
        COG5  57 hleLlehlskskslssvlselksslesLsasyerlkskvlepyeeaeklqsalkrlhqtld 117
                  ++L + +++ ks +  + el++++esL+  +e l++  +e  +++ +l+  l +  +t++
  EEA20732.1  22 SKSLYQAVDSFKSSKRAVRELREEVESLNGVLENLSQMAVEYDAQLTSLKLPLVQCAKTCE 82 
                 5778888999999999*********************999999999999988888888876 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.051
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        COG5  17 llkatnnnddteldlstplkrlnydiqeldkrlrqlitsnh 57 
                 ++ ++n  dd +  ++ + + l++ +q +dkr+++l+++++
  EEA20732.1 141 VVVTANVLDDYQKMIEEATSDLQEHLQLIDKRMQSLMQNSA 181
                 55566777888888888999999999999999999988776 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.043
                 XXXXXXXXXXXXXXXXXXXXXXXXXX....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-TT CS
        COG5  29 ldlstplkrlnydiqeldkrlrqlit....snhleLlehlskskslssvlselksslesLsasyerlkskv 95 
                   ls++ k l+  +qel++rl +l      ++hl+Ll+ +++++   s+  e+ ++ ++L+a +   +++v
  EEA20732.1 255 TRLSSNTKNLQDRLQELENRLGKLSEngddQQHLNLLQAMKEERDSISHCLEICTEASDLTATV---RTNV 322
                 5678889999999999999999888633336899999999999999888888888888888754...4455 PP

  == domain 4  score: -2.7 bits;  conditional E-value: 7.8
                 XXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXX CS
        COG5  46 dkrlrqlitsnhleLlehlskskslss.vlsel 77 
                 d+ +++l ++n+   +e+ ++++++++ v ++l
  EEA20732.1 364 DETIQKLSSDNKRAFFENQTNKTQEQKdVFHDL 396
                 566778888888888887777777766676666 PP

>> DASH_Dad2  DASH complex subunit Dad2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.1      0.89   7.3e+02      14      27 ..      53      66 ..      21      90 .. 0.53
   2 ?    5.2   0.6     0.035        29      15      46 ..     153     184 ..     149     186 .. 0.92
   3 ?    7.6   0.3    0.0063       5.1      16      43 ..     256     283 ..     254     288 .. 0.91

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.89
   DASH_Dad2 14 Lkqlrdlsdslakq 27
                L++l++++ +   q
  EEA20732.1 53 LENLSQMAVEYDAQ 66
                23333333334444 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.035
   DASH_Dad2  15 kqlrdlsdslakqleeLeeklstladgteava 46 
                 k +++ +++l++ l+ ++++++ l +++++++
  EEA20732.1 153 KMIEEATSDLQEHLQLIDKRMQSLMQNSASIQ 184
                 6799************************9996 PP

  == domain 3  score: 7.6 bits;  conditional E-value: 0.0063
   DASH_Dad2  16 qlrdlsdslakqleeLeeklstladgte 43 
                 +l++ +++l+++l+eLe++l++l+++++
  EEA20732.1 256 RLSSNTKNLQDRLQELENRLGKLSENGD 283
                 57889*******************9975 PP

>> NPV_P10  Nucleopolyhedrovirus P10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.1      0.01       8.3      22      58 ..      24      60 ..      21      76 .. 0.79
   2 ?    1.7   0.4      0.45   3.7e+02      14      34 ..     167     187 ..     141     217 .. 0.59
   3 ?    3.8   0.1     0.099        81      13      41 ..     261     289 ..     254     323 .. 0.66

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.01
     NPV_P10 22 alqqqvddvqenlpdvtelnekLdaqsaqLaeletkv 58
                +l q+vd+ ++  + v el e++++++  L++l++  
  EEA20732.1 24 SLYQAVDSFKSSKRAVRELREEVESLNGVLENLSQMA 60
                5788999999999999999999999999999998744 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.45
     NPV_P10  14 kavddkVdalqqqvddvqenl 34 
                 + +d+++++l q+ +++q+n 
  EEA20732.1 167 QLIDKRMQSLMQNSASIQANR 187
                 233444444444444444444 PP

  == domain 3  score: 3.8 bits;  conditional E-value: 0.099
     NPV_P10  13 ikavddkVdalqqqvddvqenlpdvteln 41 
                  k+++d+++ l++++ +++en  d ++ln
  EEA20732.1 261 TKNLQDRLQELENRLGKLSENGDDQQHLN 289
                 45666666666666666666666644443 PP

>> SlyX  SlyX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.2       0.2   1.6e+02       7      44 ..      41      78 ..      36      87 .. 0.71
   2 ?    6.9   0.4     0.012       9.7      33      65 ..     159     189 ..     144     189 .. 0.76
   3 ?    4.4   0.8     0.072        59      33      58 ..     261     286 ..     253     298 .. 0.74

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.2
                HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        SlyX  7 eLEiklafqedtieeLndvvaeqqqqidrlqrqlrlla 44
                eL +++  +  ++e L+++ +e + q++ l+  l + a
  EEA20732.1 41 ELREEVESLNGVLENLSQMAVEYDAQLTSLKLPLVQCA 78
                55556666677889999999999999998887666555 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.012
                 HHHHHHHHHHHHHT-XXXXXXXXXXXXXXXXXX CS
        SlyX  33 idrlqrqlrllaerlkeleessgaseaeeepPP 65 
                  + lq++l+l+ +r+++l ++s++   +  +PP
  EEA20732.1 159 TSDLQEHLQLIDKRMQSLMQNSASI--QANRPP 189
                 5689**************9997643..444454 PP

  == domain 3  score: 4.4 bits;  conditional E-value: 0.072
                 HHHHHHHHHHHHHT-XXXXXXXXXXX CS
        SlyX  33 idrlqrqlrllaerlkeleessgase 58 
                  + lq +l++l++rl +l+e+  +++
  EEA20732.1 261 TKNLQDRLQELENRLGKLSENGDDQQ 286
                 56788888888888888888866554 PP

>> DUF4363  Domain of unknown function (DUF4363)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0       4.2   3.4e+03      80      97 ..      40      57 ..      26      61 .. 0.66
   2 ?   -0.7   0.2       1.9   1.6e+03       4      33 ..     152     181 ..     143     187 .. 0.68
   3 ?    9.5   0.4    0.0013         1       7      61 ..     257     315 ..     253     332 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 4.2
     DUF4363 80 eealaelaelkfllehik 97
                 e+ +e+++l  +le++ 
  EEA20732.1 40 RELREEVESLNGVLENLS 57
                455666666666666665 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 1.9
     DUF4363   4 qnylkkstdelsekleeleeaienedweea 33 
                 q+ ++  t++l+e+l+ +++ +++   ++a
  EEA20732.1 152 QKMIEEATSDLQEHLQLIDKRMQSLMQNSA 181
                 455666777777777777777766555555 PP

  == domain 3  score: 9.5 bits;  conditional E-value: 0.0013
     DUF4363   7 lkkstdelsekleeleeai....enedweeakekleelekeWekkkkklsifiehdeld 61 
                 l++ t++l+++l+ele+ +    en+d ++  + l+++++e ++ ++ l+i +e ++l 
  EEA20732.1 257 LSSNTKNLQDRLQELENRLgklsENGDDQQHLNLLQAMKEERDSISHCLEICTEASDLT 315
                 67889999999*99999999999****************************99998875 PP

>> Spore_III_AB  Stage III sporulation protein AB (spore_III_AB)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.0    0.0014       1.1       9      90 ..      11      89 ..       9     115 .. 0.78
   2 ?    0.1   0.1      0.92   7.5e+02      41      70 ..     152     176 ..     139     226 .. 0.61
   3 ?    1.3   0.3      0.39   3.2e+02     104     140 ..     262     298 ..     235     317 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.0014
                  XXXXXXXXXXXXXXXXHHHHHHHHHHHHHHHHHHHHHH-SS-HHHHHHHHHHCS-TTHHHH...HHHHHHHHH.STSS-HHHHHH CS
  Spore_III_AB  9 llactgiGfalakrlkrrlkeleelkralellegeirygatpLpealeklaeksesplsef...feevaerleekegesfeeawe 90
                  l+a tg+ f+++k l + ++  +  kra++ l+ e++  +  L++ l+++a +++ +l ++   + ++a+       e+fe++++
    EEA20732.1 11 LVALTGFAFQASKSLYQAVDSFKSSKRAVRELREEVESLNGVLEN-LSQMAVEYDAQLTSLklpLVQCAKT-----CEEFERVIS 89
                  57899************************************9966.9999988888777775554444443.....344444444 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.92
                   HHHHHH-SS-HHHHHHHHHHCS-TTHHHHH CS
  Spore_III_AB  41 egeirygatpLpealeklaeksesplseff 70 
                   +  i+ + + L+e l+ + ++++s     +
    EEA20732.1 152 QKMIEEATSDLQEHLQLIDKRMQS-----L 176
                   444444445555555555544444.....2 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.39
                   HHHHHHHHHHHHHHT--SHHHHHHHHHHHHHHHHHHH CS
  Spore_III_AB 104 kedkeilkelgeslgysdregqlkalelaleeleeei 140
                   k+ ++ l+el + lg+++ +g  ++  ++l+ ++ee 
    EEA20732.1 262 KNLQDRLQELENRLGKLSENGDDQQHLNLLQAMKEER 298
                   4446677788888888887777777777777776665 PP

>> KxDL  Uncharacterized conserved protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0      0.13     1e+02      35      76 ..      17      58 ..      11      63 .. 0.83
   2 ?    5.4   0.7     0.027        22      22      62 ..     145     185 ..     139     187 .. 0.85
   3 ?    5.0   1.0     0.035        29      23      67 ..     255     301 ..     234     307 .. 0.80

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.13
        KxDL 35 lnalsqerlaklrarfkqgtkllkevkkdLesifkkirslka 76
                +  ++++ l ++ + fk+ +++++e++++ es++  +++l +
  EEA20732.1 17 FAFQASKSLYQAVDSFKSSKRAVRELREEVESLNGVLENLSQ 58
                555788999999999**************9999888887766 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.027
        KxDL  22 sgrlnkknreLlelnalsqerlaklrarfkqgtkllkevkk 62 
                  ++l + +++++e    +qe+l+ + +r+++ ++ + ++++
  EEA20732.1 145 ANVLDDYQKMIEEATSDLQEHLQLIDKRMQSLMQNSASIQA 185
                 56788889999999999999999999999999999988876 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.035
        KxDL  23 grlnkknreLlelnalsqerlaklrarf..kqgtkllkevkkdLesi 67 
                 +rl + ++ L++  +++++rl kl+++   +q+ +ll+ +k++ +si
  EEA20732.1 255 TRLSSNTKNLQDRLQELENRLGKLSENGddQQHLNLLQAMKEERDSI 301
                 57888899999999999999999988652267778899999876665 PP

>> ING  Inhibitor of growth proteins N-terminal histone-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.0      0.69   5.6e+02       2      47 ..      49      94 ..      48     110 .. 0.83
   2 ?    7.8   1.5    0.0061         5      16      73 ..     148     205 ..     145     221 .. 0.78
   3 ?    4.1   0.7     0.083        68      23      95 ..     257     330 ..     251     336 .. 0.73
   4 ?   -1.8   0.1       5.7   4.7e+03      38      57 ..     364     391 ..     349     399 .. 0.58

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.69
                HHHHHTSGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS CS
         ING  2 LedyldsvenLPlelqrnltelreiDakvqellkeidskiekflkn 47
                L+  l++++++  e   +lt l+   +++ ++ +e ++ i+k + +
  EEA20732.1 49 LNGVLENLSQMAVEYDAQLTSLKLPLVQCAKTCEEFERVISKCVGH 94
                78899999999************99999999999999999999833 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0061
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS..S-HHHHHHHHHHHHHHHHHHHHHH CS
         ING  16 lqrnltelreiDakvqellkeidskiekflkngslqknekeeelsriqeelkeaqell 73 
                 l ++ + + e    +qe+l+ id++++++++n++  + ++  e+++i ee + + ++l
  EEA20732.1 148 LDDYQKMIEEATSDLQEHLQLIDKRMQSLMQNSASIQANRPPEVEEIVEEKRSIRQCL 205
                 5567778888889999999999999999998888888888888888888877777765 PP

  == domain 3  score: 4.1 bits;  conditional E-value: 0.083
                 HHHHHHHHHHHHHHHHHHHHHHHTS..S-HH.HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
         ING  23 lreiDakvqellkeidskiekflkngslqkn.ekeeelsriqeelkeaqelldeKiqlaqqaldlvdkhlrrLd 95 
                 l    + +q+ l+e+++++ k+++ng+ q++ +  +++++ +++++++ e+  e   l+ ++   v ++++  d
  EEA20732.1 257 LSSNTKNLQDRLQELENRLGKLSENGDDQQHlNLLQAMKEERDSISHCLEICTEASDLTATVRTNVYEEVKSAD 330
                 55556789999999999999999555544441566666688888888888888888888888877777776655 PP

  == domain 4  score: -1.8 bits;  conditional E-value: 5.7
                 HHHHHHHH........TS..S-HHHHHH CS
         ING  38 dskiekfl........kngslqknekee 57 
                 d+ i+k++        +n++++ +e+++
  EEA20732.1 364 DETIQKLSsdnkraffENQTNKTQEQKD 391
                 5555555555444445444444444444 PP

>> DUF2205  Short coiled-coil protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.1      0.74   6.1e+02      14      37 ..      35      58 ..      18      70 .. 0.63
   2 ?    2.5   0.8      0.18   1.5e+02       9      37 ..     150     178 ..     145     187 .. 0.72
   3 ?    7.0   0.3    0.0073         6      17      44 ..     253     280 ..     243     286 .. 0.85
   4 ?    2.7   0.1      0.16   1.3e+02      41      72 ..     321     352 ..     288     355 .. 0.76

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.74
     DUF2205 14 erearerLqqqakeLqssLqaLae 37
                ++ a  +L++ +++L+  L++L++
  EEA20732.1 35 SKRAVRELREEVESLNGVLENLSQ 58
                333444566666666666666665 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.18
     DUF2205   9 dveklerearerLqqqakeLqssLqaLae 37 
                 d +k+ +ea  +Lq++ + + + +q+L++
  EEA20732.1 150 DYQKMIEEATSDLQEHLQLIDKRMQSLMQ 178
                 66777778888888888777777777766 PP

  == domain 3  score: 7.0 bits;  conditional E-value: 0.0073
     DUF2205  17 arerLqqqakeLqssLqaLaervdeVke 44 
                  r+rL++  k+Lq+ Lq+L +r  +  e
  EEA20732.1 253 FRTRLSSNTKNLQDRLQELENRLGKLSE 280
                 699******************9877655 PP

  == domain 4  score: 2.7 bits;  conditional E-value: 0.16
     DUF2205  41 eVkeehdKLesenrfLqqYIgdLmstskvtqs 72 
                 +V ee +  ++  ++  + IgdL+s+ ++t  
  EEA20732.1 321 NVYEEVKSADNSHQLVVSTIGDLISAKHITTG 352
                 5677777778888999999*******999974 PP

>> Seryl_tRNA_N  Seryl-tRNA synthetase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   0.0    0.0068       5.6      54     100 ..      24      70 ..      19      75 .. 0.83
   2 ?    2.9   0.9      0.15   1.3e+02      35      67 ..     149     185 ..     137     221 .. 0.54
   3 ?    3.9   0.8     0.077        63      40      81 ..     256     296 ..     250     318 .. 0.65

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0068
                   HHHHHCCCCCCTTS-TCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N  54 elskeIgkakkkkedaeeliaevkelkeelkaleaelkeleaelekl 100
                   +l +++ + k +k    el++ev++l+  l++l++   e +a+l++l
    EEA20732.1  24 SLYQAVDSFKSSKRAVRELREEVESLNGVLENLSQMAVEYDAQLTSL 70 
                   55567778888899999999999999999999999999999999876 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.15
                   HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTT....S CS
  Seryl_tRNA_N  35 dekrrelqveleelqaerNelskeIgkakkkk....e 67 
                   d+ ++ ++ ++ +lq+    + k +++++++     +
    EEA20732.1 149 DDYQKMIEEATSDLQEHLQLIDKRMQSLMQNSasiqA 185
                   4555555555555555555555555555555543331 PP

  == domain 3  score: 3.9 bits;  conditional E-value: 0.077
                   HHHHHHHHHHHHHHHHHHHCCCCCCTTS-TCCCCCCCHHHHH CS
  Seryl_tRNA_N  40 elqveleelqaerNelskeIgkakkkkedaeeliaevkelke 81 
                   +l + + +lq +  el +  gk++++++d +  ++  +++ke
    EEA20732.1 256 RLSSNTKNLQDRLQELENRLGKLSENGDDQQ-HLNLLQAMKE 296
                   5667778888888888888888888883333.3333333333 PP

>> Plk4_PB2  Polo-like Kinase 4 Polo Box 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.2      0.89   7.3e+02      64      92 ..      63      91 ..      19     102 .. 0.62
   2 ?   10.3   0.3    0.0011       0.9      40      93 ..     163     219 ..     145     230 .. 0.75
   3 ?    1.7   0.2      0.51   4.2e+02      63      93 ..     285     315 ..     242     332 .. 0.53

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.89
    Plk4_PB2 64 lsselkkllehaeeclkqclklesalssl 92
                ++ +l +l   + +c k+c + e+++s+ 
  EEA20732.1 63 YDAQLTSLKLPLVQCAKTCEEFERVISKC 91
                34444444445567777777777777765 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.0011
    Plk4_PB2  40 gekvkiieksgksltleseeeleslsselkklleh...aeeclkqclklesalssle 93 
                 +e++++i+k  +sl  +s++ +++ ++e+++++e    +++cl  c ++++++++ +
  EEA20732.1 163 QEHLQLIDKRMQSLMQNSASIQANRPPEVEEIVEEkrsIRQCLAICTQVSQLIEAYQ 219
                 4579*******9**999999************9861114556666666666665555 PP

  == domain 3  score: 1.7 bits;  conditional E-value: 0.51
    Plk4_PB2  63 slsselkkllehaeeclkqclklesalssle 93 
                 + + +l + ++  +++ ++cl++ +  s l+
  EEA20732.1 285 QQHLNLLQAMKEERDSISHCLEICTEASDLT 315
                 2222333334444445555666555555444 PP

>> YlqD  YlqD protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.1         3   2.5e+03      87     101 ..      40      54 ..      19      84 .. 0.54
   2 ?    9.5   3.0    0.0014       1.2      11      73 ..     141     203 ..     138     221 .. 0.87
   3 ?    3.7   0.2      0.09        73      23      72 ..     255     301 ..     245     348 .. 0.77
   4 ?    1.4   0.2      0.46   3.8e+02      31      61 ..     362     392 ..     352     405 .. 0.70

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 3
        YlqD  87 qkLelgsevkqgqve 101
                 ++L  + e  +g +e
  EEA20732.1  40 RELREEVESLNGVLE 54 
                 222222222222222 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.0014
        YlqD  11 aivTeklKeelqqqlqaqieqldkelqqLefqakrlikeikkqsaqqieeiqeqvekekserl 73 
                 ++vT ++ ++ q+ ++++ + l++ lq ++  ++ l+++ ++ +a++  e++e ve+++s r+
  EEA20732.1 141 VVVTANVLDDYQKMIEEATSDLQEHLQLIDKRMQSLMQNSASIQANRPPEVEEIVEEKRSIRQ 203
                 799***************************************999999999999999987664 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.09
        YlqD  23 qqlqaqieqldkelqqLefqakrlikeikkqsaqqieeiqeqvekekser 72 
                 ++l+++ ++l+  lq+Le  + +l ++      qq+ ++ + +++e++ +
  EEA20732.1 255 TRLSSNTKNLQDRLQELENRLGKLSENGDD---QQHLNLLQAMKEERDSI 301
                 678899999999999999999999777765...56666666666666554 PP

  == domain 4  score: 1.4 bits;  conditional E-value: 0.46
        YlqD  31 qldkelqqLefqakrlikeikkqsaqqieei 61 
                   d+ +q+L+ + kr+  e++++++q+++ +
  EEA20732.1 362 MSDETIQKLSSDNKRAFFENQTNKTQEQKDV 392
                 4567778888888888888877777665554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (413 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1980  (0.110436); expected 358.6 (0.02)
Passed bias filter:                      952  (0.0530983); expected 358.6 (0.02)
Passed Vit filter:                       108  (0.00602376); expected 17.9 (0.001)
Passed Fwd filter:                        31  (0.00172904); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              22  [number of targets reported over threshold]
# CPU time: 0.72u 0.32s 00:00:01.04 Elapsed: 00:00:00.47
# Mc/sec: 2632.55
//
Query:       EEA20733.1  [L=165]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    8.6e-20   71.1   0.7    1.6e-19   70.2   0.2    1.6  2  zf-3CxxC    Zinc-binding domain
  ------ inclusion threshold ------
      0.028   13.9   0.2      0.033   13.6   0.2    1.1  1  ESAG1       ESAG protein


Domain annotation for each model (and alignments):
>> zf-3CxxC  Zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0      0.42   3.8e+03      64      80 ..      21      38 ..       5      50 .. 0.50
   2 !   70.2   0.2   1.8e-23   1.6e-19       2      98 ..      52     147 ..      51     149 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.42
    zf-3CxxC 64 kvlrnlvk.kiekkfyke 80
                +v+r l + +++ +fy++
  EEA20733.1 21 HVVRLLEEdDLHLNFYES 38
                454444443444444443 PP

  == domain 2  score: 70.2 bits;  conditional E-value: 1.8e-23
    zf-3CxxC   2 akgrfeCs..kCskk.WtSakvavtfrvylerqkkkgevkvrlfgQrCkkCkkleepkldeeevekvlrnlvk....kiekkfykekrkkPykvHerel 93 
                 ++grf  +  +C+ + WtS+++avt+r+y     ++g+++vr+++QrCk+Ck+l++pkl+e+ +e+ ++++++    + e + ++ ++++P   H++el
  EEA20733.1  52 VTGRFVYRnpSCGVNaWTSGRIAVTIRLY-----TGGKYNVRVYHQRCKSCKRLSRPKLNETYAERTAYRIKNwhgiEQEARPHSGNSNGP---HNSEL 142
                 78999998889**999*************.....4578***********************99**********884444444455566888...***** PP

    zf-3CxxC  94 CeaCk 98 
                 Ce+C 
  EEA20733.1 143 CEGCG 147
                 ****6 PP

>> ESAG1  ESAG protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.2   3.7e-06     0.033      71     155 ..      36     122 ..      12     128 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 3.7e-06
       ESAG1  71 veadeeakCkeeelkkvkefkvkCgdktCple...egvsestlkkykdgcleinvlkgsvskClnlprdnLyksGavknssdvleWre 155
                  e+de++ C+e+  ++v++  v   + +C ++   +g  + t++ y  g  ++ v+++  ++C  l r +L +  a++++  + +W++
  EEA20733.1  36 YESDESETCDETWDTNVTGRFVY-RNPSCGVNawtSGRIAVTIRLYTGGKYNVRVYHQRCKSCKRLSRPKLNETYAERTAYRIKNWHG 122
                 46666677887777777664433.344454441115666789********************************************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (165 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       696  (0.0388198); expected 358.6 (0.02)
Passed bias filter:                      521  (0.0290591); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.25s 00:00:00.72 Elapsed: 00:00:00.44
# Mc/sec: 1121.23
//
Query:       EEA20734.1  [L=448]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.2e-10   40.2   2.5    4.5e-07   29.4   0.2    3.0  3  Dynamin_M  Dynamin central region
    4.8e-07   29.9   0.0    1.6e-06   28.2   0.0    2.0  1  GED        Dynamin GTPase effector domain


Domain annotation for each model (and alignments):
>> Dynamin_M  Dynamin central region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.4   0.2     5e-11   4.5e-07      33     147 ..       7     122 ..       2     156 .. 0.81
   2 !    8.3   0.0   0.00013       1.2     168     267 ..     205     303 ..     185     316 .. 0.86
   3 ?    2.0   0.2     0.011        96     169     225 ..     311     371 ..     274     382 .. 0.74

  Alignments for each domain:
  == domain 1  score: 29.4 bits;  conditional E-value: 5e-11
   Dynamin_M  33 ieealkkEkaFFeshpayrkl.adkaGtpyLakkLnqiLvehIrkslPelkkkineklqklekeleelgeskpsdeektklllqlitkfkedfkklieG 130
                 i+++  +E++F  + p+ + + +d+ G+++L+++L+++ +   r+ +P+      ++ + +++el++lg +++++e++ ++ll ++ +f++  +k+++ 
  EEA20734.1   7 ITDRDAAEENFRLTAPW-NIIsKDRFGIRALKTRLQETVTANAREAFPHVA----KSSEIAKNELQSLGAERDTQEQQLAYLLGIMASFQDITQKALST 100
                 66777889999999987.7888**************************865....56778999******9999999*********************99 PP

   Dynamin_M 131 e.se...vs.tkelsggarire 147
                 + s     + + el+  +ri +
  EEA20734.1 101 NySYsgfFDsHTELRFATRIVN 122
                 9622567444999999999854 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.00013
   Dynamin_M 168 deeirtairnsrGrelplfvpekaFealvkkqikkleepalkcvelVyeelekivek.lek.elkrFpnLreeikevvedllreqeeptkemienliem 264
                 +++i++ +rnsrG e+ + ++ +   + +k+q + + ++a+ ++  V +   +++ + l+  + +   ++r+++++v+ + l  + +++ + ++ l+++
  EEA20734.1 205 RSWIENQYRNSRGFEI-GTLNVTLISTTMKQQSDHWTSIAHGYISDVVTMTHRFILTaLDIaCPD--DRVRRNLMSVLMERLLDRYKNAIDKVNFLLNV 300
                 689************9.5789999********************999999999999955556544..89************************999999 PP

   Dynamin_M 265 ela 267
                 e++
  EEA20734.1 301 ERS 303
                 986 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.011
   Dynamin_M 169 eeirtairnsrGrelplfvpekaFealvkkqikkleepalkcv....elVyeelekivekl 225
                 +  +  i+++r ++ +  v +k+F    + ++ +le++ +++     + + +e+ +i+++ 
  EEA20734.1 311 HYLNSNIEKCRQKRFSSVVAKKTFNDNSHGKVVRLEDITHQHHmsneTHAVQEIHDILQSY 371
                 5556678899999999999999999999999999999999998888877888888888773 PP

>> GED  Dynamin GTPase effector domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.2   0.0   1.8e-10   1.6e-06       2      89 ..     357     447 ..     356     448 .] 0.90

  Alignments for each domain:
  == domain 1  score: 28.2 bits;  conditional E-value: 1.8e-10
                 XXXXTTHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHTHHHHCCC...CCHHHCCTTSGGGHHHHT---SCHCCCCHHHHHHHHHHHHHCCCC CS
         GED   2 eeseveeirslvksYfnivrktiadqiPk.aimhllvneakesl...qkellakLykkedldeLLkEdeeiaekRkelkkrlealkkAreil 89 
                 e++ v+ei   ++sY++++rk+  d+i + a+ ++lv++ +  +     +++ +L k++ l+++  E+ ++++kR++l k+++ l++Ar++l
  EEA20734.1 357 ETHAVQEIHDILQSYYKVARKRFVDNICLhAVDYHLVTDPETPMglfSPSFVGSLSKEQ-LEDIAGEEGALKRKRRQLGKKIKDLQEARKVL 447
                 67889**********************854999*****998876333789*****9877.8****************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (448 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       906  (0.0505327); expected 358.6 (0.02)
Passed bias filter:                      493  (0.0274974); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.43
# Mc/sec: 3127.35
//
Query:       EEA20735.1  [L=252]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    6.9e-32  110.8   0.0    1.7e-31  109.6   0.0    1.6  1  Dynamin_N  Dynamin family
    3.8e-05   23.7   0.1    0.00034   20.7   0.1    2.0  1  MMR_HSR1   50S ribosome-binding GTPase
  ------ inclusion threshold ------
      0.033   14.0   0.0      0.044   13.6   0.0    1.2  1  AAA_21     AAA domain, putative AbiEii toxin, Type IV TA syst
      0.094   12.1   0.0       0.14   11.5   0.0    1.2  1  TniB       Bacterial TniB protein
       0.11   12.9   0.0       0.13   12.6   0.0    1.2  1  AAA_16     AAA ATPase domain
       0.12   12.2   0.0       0.27   11.0   0.0    1.6  1  AAA_29     P-loop containing region of AAA domain
       0.13   11.8   0.0         14    5.2   0.0    2.3  2  FeoB_N     Ferrous iron transport protein B


Domain annotation for each model (and alignments):
>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  109.6   0.0   6.6e-35   1.7e-31       1     167 [.      38     234 ..      38     235 .. 0.82

  Alignments for each domain:
  == domain 1  score: 109.6 bits;  conditional E-value: 6.6e-35
                 EEEEEBTTTTHHHHHHHHHTS--S---SSS---S-EEEEECCT---C....................CS...SSEEEET-EB--CHHHHHHHHHHHHHH CS
   Dynamin_N   1 iavvGsqSsGKSSvlnaLlgedilprgpnptTrrplelqlgeeeeas....................eravkeelkekekkledfsevreeieketeki 79 
                 +avvG+qSsGKSSvl+ L++ + +pr+++++Tr  +++  +++e+ +                    e++v++ +  + + ++++    ++++  +  +
  EEA20735.1  38 LAVVGDQSSGKSSVLEGLTRLA-FPRDSGLCTRFATQIIFRRTETGErtitatiipgsnatnasqlrEWKVTDLQSLDVTAFSKMMTEVHALMGLSISK 135
                 69********************.8****************77777666777777776655533333344444444444555555555555555555556 PP

                 HTSSSS--SS-EEEEEEETTS-SEEEEE---B-SSSGTTS..........HHHHHHH.STTEEEEEEEETTS-CCC-CHHHHHHHHSTTBTTEEEEEE- CS
   Dynamin_N  80 agankgiskkvillkilsllvkgltlvDlPGldsvnkrdq..........elvkeyi.kkadiilavtsanhdlsnsealflarevdpkgkrtivvltk 167
                 ++++ ++s++v+ l+i+++ +++l+++D+PG+ ++ +              +v ey+ ++++i+l v++an+d++++e  ++arevdp+g rt++vltk
  EEA20735.1 136 EDSLPTFSSNVLRLEICGPEEDHLSVIDVPGIFRNTTPGVttkedkdmvrGMVLEYMrNPRSIMLTVVPANVDIATQEIIDMAREVDPEGNRTLGVLTK 234
                 6677788888**********************99665555589999****************************************************9 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.7   0.1   1.3e-07   0.00034       2     104 ..      38     224 ..      37     234 .. 0.72

  Alignments for each domain:
  == domain 1  score: 20.7 bits;  conditional E-value: 1.3e-07
                 EEEEESTTSSHHHHHHHHHTSTEEESSSTTSSSSEEEEEEEETTEE..................................................... CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltgekaivsdkpgtTrdinegrvklkgke..................................................... 47 
                  a+vG   +GKS+++  lt+  a   d   +Tr  +++ ++    e                                                     
  EEA20735.1  38 LAVVGDQSSGKSSVLEGLTR-LAFPRDSGLCTRFATQIIFRRT--Etgertitatiipgsnatnasqlrewkvtdlqsldvtafskmmtevhalmglsi 133
                 69*****************8.5666677777777776666622..123345666666666777788888888999999999999999999********* PP

                 .........................EEEEECGGCS.......S.HHHHHH..HHHHHHHHHHCTSEEEEEEETTTTCSHHHHHHHHHHHHH...T CS
    MMR_HSR1  48 .........................ielvDtpGli.......e.gaseek..glgkaflaleeadlillvvdaseeklkpldeeleellee...a 104
                                          + ++D+pG++         +++++   g+  ++ ++ + +++l vv a+   ++   +e+ ++ +e   +
  EEA20735.1 134 skedslptfssnvlrleicgpeedhLSVIDVPGIFrnttpgvTtKEDKDMvrGMVLEYMRNPR-SIMLTVVPAN---VDIATQEIIDMAREvdpE 224
                 *********************************855544433122233334577777776666.8888888855...444556666666554443 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.0   1.7e-05     0.044       3      26 ..      39      72 ..      38     103 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 1.7e-05
      AAA_21  3 vliGpNgsGKSnLLdaldllarl..........d 26
                +++G+ +sGKS++L+ l  la+            
  EEA20735.1 39 AVVGDQSSGKSSVLEGLTRLAFPrdsglctrfaT 72
                68****************9987555554444433 PP

>> TniB  Bacterial TniB protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   5.6e-05      0.14      19     119 ..      17     122 ..       8     129 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 5.6e-05
        TniB  19 ilerLeeLley..pkrkrmpnlllvGdsnnGKtmivekFarlhppekdedaekvpvlvvqappkpdekrlyaaiL...ealgaplkararvskleqqvl 112
                 +l+++++L++    + +  p+l +vGd+  GK++++e  +rl  p+++   +++   ++  +++  e+ + a i+   +a +a    +++v++l++  +
  EEA20735.1  17 LLDKIDKLFACnvGEYTNLPQLAVVGDQSSGKSSVLEGLTRLAFPRDSGLCTRFATQIIFRRTETGERTITATIIpgsNATNASQLREWKVTDLQSLDV 115
                 5677777765521456788*******************9999999888887777777777777778888888887332334444444556666666666 PP

        TniB 113 rllrelk 119
                 + +++++
  EEA20735.1 116 TAFSKMM 122
                 6666665 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   5.3e-05      0.13      25      63 ..      36      75 ..      17     159 .. 0.70

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 5.3e-05
      AAA_16 25 elvllsGesGvGKsslvrellralekdg.giflrgkcdql 63
                + + ++G++ +GKss+++ l r +  ++ g+++r  ++  
  EEA20735.1 36 PQLAVVGDQSSGKSSVLEGLTRLAFPRDsGLCTRFATQII 75
                6689**************9999776663244444443333 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00011      0.27      25      49 ..      38      62 ..      29      67 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00011
      AAA_29 25 tlltGpsGsGKSTllDAiqalLvpa 49
                  ++G++ sGKS++l  ++ l  p+
  EEA20735.1 38 LAVVGDQSSGKSSVLEGLTRLAFPR 62
                5789**************9999887 PP

>> FeoB_N  Ferrous iron transport protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   0.0    0.0055        14       3      22 ..      38      57 ..      36      61 .. 0.90
   2 ?    4.4   0.0    0.0095        24      45      75 ..     155     189 ..     144     220 .. 0.71

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.0055
                EEEEESTTSSHHHHHHHHHT CS
      FeoB_N  3 valvGnpnvGkttlfnaltg 22
                +a+vG++ +Gk+++++ lt 
  EEA20735.1 38 LAVVGDQSSGKSSVLEGLTR 57
                799*************9997 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.0095
                 TTEEEEEEE----SSS....SSSSHHHHHHHHHHH CS
      FeoB_N  45 kgkeveivDlPGiYsl....sayseeekvardfll 75 
                 ++++++++D+PGi+       ++ e++ ++r ++l
  EEA20735.1 155 EEDHLSVIDVPGIFRNttpgVTTKEDKDMVRGMVL 189
                 567899*******9873333334556666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (252 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       376  (0.0209716); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.44u 0.29s 00:00:00.73 Elapsed: 00:00:00.41
# Mc/sec: 1859.62
//
Query:       EEA20736.1  [L=760]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.1e-35  121.7   0.2    3.1e-35  121.7   0.2    1.8  2  Dynamin_N  Dynamin family
    7.2e-24   84.5   0.1    6.5e-18   65.0   0.0    2.7  2  Dynamin_M  Dynamin central region
    4.3e-05   23.6   0.1    0.00041   20.4   0.1    2.5  1  MMR_HSR1   50S ribosome-binding GTPase
  ------ inclusion threshold ------
      0.029   14.5   0.1       0.14   12.3   0.1    2.3  1  GED        Dynamin GTPase effector domain
      0.037   13.7   1.6        0.9    9.2   0.0    3.0  3  AAA_15     AAA ATPase domain
       0.11   12.4   0.6       0.19   11.6   0.6    1.4  1  NACHT_N    N-terminal domain of NWD NACHT-NTPase
       0.13   12.5   0.0        1.1    9.5   0.0    2.5  2  Roc        Ras of Complex, Roc, domain of DAPkinase


Domain annotation for each model (and alignments):
>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.7   0.2   1.2e-38   3.1e-35       1     167 [.      61     256 ..      61     257 .. 0.91
   2 ?   -3.1   0.1       2.7     7e+03     134     141 ..     600     607 ..     579     647 .. 0.55

  Alignments for each domain:
  == domain 1  score: 121.7 bits;  conditional E-value: 1.2e-38
                 EEEEEBTTTTHHHHHHHHHTS--S---SSS---S-EEEEECCT---C...........CS...SSEEEET-EB--CHHHHHHHHHHHHHHHTSSSS--S CS
   Dynamin_N   1 iavvGsqSsGKSSvlnaLlgedilprgpnptTrrplelqlgeeeeas...........eravkeelkekekkledfsevreeieketekiagankgisk 88 
                 i+v+G+qS+GKSSvl+aL++ + +pr+ n++Tr p+e+ l++ ++ s           + +++++++e+++++++f+e+ + ++k+te    ++ +   
  EEA20736.1  61 IVVCGDQSAGKSSVLEALTEIP-FPRKDNLCTRYPTEIILRQGKSDSlqirvipdperSVEEQKSIREFRENITSFEELPKVMDKATEIMGINKVNG-- 156
                 89********************.7**************99887776677889888866555667788889999999999999999999977333333.. PP

                 S...........-EEEEEEETTS-SEEEEE---B-SSSGTTS.........HHHHHHH.STTEEEEEEEETTS-CCC-CHHHHHHHHSTTBTTEEEEEE CS
   Dynamin_N  89 k...........villkilsllvkgltlvDlPGldsvnkrdq.........elvkeyi.kkadiilavtsanhdlsnsealflarevdpkgkrtivvlt 166
                             v++++i ++++++lt+vDlPG+ +++++d+         e++++yi ++++i lav sa +d +n+  l+  r+ dpkg+rt++++t
  EEA20736.1 157 SgidlrqafardVLSVEIEGPNRPQLTVVDLPGIVQSQTKDTsqadvqltvEITESYIsQPRTICLAVISATNDYANQPILNKVRQFDPKGERTLGIIT 255
                 2447889******************************************************************************************** PP

                 - CS
   Dynamin_N 167 k 167
                 k
  EEA20736.1 256 K 256
                 9 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 2.7
                 EEEETTS- CS
   Dynamin_N 134 avtsanhd 141
                 +v ++nh 
  EEA20736.1 600 YVINYNHY 607
                 33333332 PP

>> Dynamin_M  Dynamin central region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.0   0.0   2.5e-21   6.5e-18       3     132 ..     272     405 ..     270     465 .. 0.80
   2 !   17.8   0.0   5.9e-07    0.0015      93     278 ..     423     610 ..     414     617 .. 0.72

  Alignments for each domain:
  == domain 1  score: 65.0 bits;  conditional E-value: 2.5e-21
   Dynamin_M   3 dilenkvipLklGYvgVvnRsqkdInkkksieealkkEkaFFeshpayrkladkaGtpyLakkLnqiLvehIrkslPelkkkineklqklekeleelge 101
                 ++++n++i   lG+ + +nRs ++  ++ si+e+ ++E++FF++    ++   + G+  L  +L++ L++h+++ lP l++++ e l +++kel+++ e
  EEA20736.1 272 RLAKNEDIYFTLGWHILKNRSYEE--AEFSIQERKDSESKFFRQSRCGTLSPAHIGISSLVDRLSKMLFSHVQQALPLLHEELDEALGRINKELAAIRE 368
                 5689********************..79*****************996555***********************************************9 PP

   Dynamin_M 102 skpsdeektklllqlitkfkedfkklieGe......s 132
                 ++ s +e + +l ql  +f e  k++++G+      +
  EEA20736.1 369 PRASPDECKIFLAQLALNFYEVCKAAVNGHyedsyfR 405
                 888866***********************95433330 PP

  == domain 2  score: 17.8 bits;  conditional E-value: 5.9e-07
   Dynamin_M  93 ekeleelgeskpsde..ektklllqlitkfkedfkklieGe.sevs.tkelsggarireiFnetlekslekidpleelsdeeirtairnsrGrelplfv 187
                 ++e++ l ++  +d   +  k+ ++ ++ +++d ++++  + +ev  ++e + g +   +++++++  l ++ + ++ +++++++++ ++rGrel + +
  EEA20736.1 423 RAEIQLLNQKFAEDVrqKGHKYHINGLRGVSSDAEQTVPQNvDEVPsESEGETGIKTPGELKSHIKLMLPETMSHRK-AMKWVNDVVVRTRGRELLGNF 520
                 55555555555555544455666777777778888888555466655888888888888888888877777555554.899****************** PP

   Dynamin_M 188 pekaFealvkkqikkleepalkcvelVyeelekiveklekelkrFpnLreeikevvedllreqeeptkemienliemelayintnhpdfig 278
                 ++ +   l+ +q +k+   a +++++++++ +++++++ ++++     ++   +++ dl ++++  t + +e++++  ++y+   ++ + +
  EEA20736.1 521 NPLVIAELFWEQSSKWDVFAKEHIDQASSACQRFLKHALDSMAPRDIFHRLWPRILGDLTTKRQHAT-DELEKILKDIRSYVINYNHYYTD 610
                 *************************************555554444455555555666655555444.44677777777777777777766 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.1   1.6e-07   0.00041       1      92 [.      60     233 ..      60     256 .. 0.76

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 1.6e-07
                 EEEEEESTTSSHHHHHHHHHTSTEEESSSTTSSSSEEEEEEEETTEE.................................................... CS
    MMR_HSR1   1 evaivGrpNvGKStLinaltgekaivsdkpgtTrdinegrvklkgke.................................................... 47 
                 ++++ G   +GKS+++ alt+      + + +Tr ++e+ ++ ++++                                                    
  EEA20736.1  60 QIVVCGDQSAGKSSVLEALTE-IPFPRKDNLCTRYPTEIILRQGKSDslqirvipdpersveeqksirefrenitsfeelpkvmdkateimginkvngs 157
                 5899****************8.5566788899*******99954433788899999999999999999******************************* PP

                 ........................EEEEECGGCSS.......HHHHHH..HHHHHHHHHHCTSEEEEEEETTTTCSHH CS
    MMR_HSR1  48 ........................ielvDtpGlie.......gaseek..glgkaflaleeadlillvvdaseeklkp 92 
                                         +++vD+pG+++       +a+ +   ++++++ +  +  + l v++a+ +++++
  EEA20736.1 158 gidlrqafardvlsveiegpnrpqLTVVDLPGIVQsqtkdtsQADVQLtvEITESYISQPR-TICLAVISAT-NDYAN 233
                 ********************************87533323222222222234444444333.7777777766.33433 PP

>> GED  Dynamin GTPase effector domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.1   5.6e-05      0.14      23      92 .]     689     757 ..     668     757 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 5.6e-05
                 HHHHHHHHHHHHHHTHHHHCCCCCHHHCCTTSGGGHHHHT---SCHCCCCHHHHHHHHHHHHHCCCCCHH CS
         GED  23 tiadqiPkaimhllvneakeslqkellakLykkedldeLLkEdeeiaekRkelkkrlealkkAreilsev 92 
                  ia+   ++i  ++++ ++e +   ++a++ + +++  L  E ++++++R+ l  rl+ lk+ reil e+
  EEA20736.1 689 FIANVTIQVIERHVLQGLEEIFCPLIVANISDADAVA-LALEPAATTKQRDYLSGRLAKLKQGREILREF 757
                 57888899999999999999999999****9999876.899*************************9875 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.0   0.00035       0.9      26      43 ..      61      78 ..      53     159 .. 0.90
   2 ?   -0.1   0.0      0.23   5.9e+02     235     300 ..     338     410 ..     267     445 .. 0.71
   3 ?    1.2   0.4     0.091   2.3e+02     242     280 ..     587     624 ..     519     701 .. 0.53

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00035
      AAA_15 26 tvliGkNnsGKSsileal 43
                 v++G +++GKSs+leal
  EEA20736.1 61 IVVCGDQSAGKSSVLEAL 78
                589**************9 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.23
      AAA_15 235 eeelteklkeiqeklkeidkklaeelk..kilkkkidkikkfnykgkkneeieik.....ddeelplnknGsG 300
                    ++++l+ ++e+l+e+ + +++el+  ++   + d+ k f ++ + n++   k     + e++++ +nG G
  EEA20736.1 338 FSHVQQALPLLHEELDEALGRINKELAaiREPRASPDECKIFLAQLALNFYEVCKaavngHYEDSYFRYNGKG 410
                 5567888888999999999999999996633333444455556666666666666777774444455555544 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.091
      AAA_15 242 lkeiqeklkeidkklaeelkkilkkkidkikkfnykgkk 280
                  +e+++ lk+i +++  +++  ++++i+k+ ++    + 
  EEA20736.1 587 TDELEKILKDIRSYV-INYNHYYTDIIKKSRYERRRAQM 624
                 222222222222222.22222222222222222111111 PP

>> NACHT_N  N-terminal domain of NWD NACHT-NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.6   7.3e-05      0.19       2      72 ..     570     639 ..     569     656 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 7.3e-05
     NACHT_N   2 rLWdrAYdslkeseaelvkeYekilseeeekesskkeeeseekeeeseeekrqeqlkrlvekglkrvekkk 72 
                 rLW r   +l+++ ++  +e ekil ++ ++  ++ ++  ++ +++s+ e+r++q+++ +ek+ +  + + 
  EEA20736.1 570 RLWPRILGDLTTKRQHATDELEKIL-KDIRSYVINYNHYYTDIIKKSRYERRRAQMQKCIEKATRNKKVSG 639
                 89***********************.588888899999999999******************986655444 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.0   0.00042       1.1       2      27 ..      61      86 ..      60     100 .. 0.87
   2 ?   -1.1   0.0       0.8   2.1e+03      71     117 ..     208     256 ..     197     259 .. 0.67

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00042
                EEEESSTTSSHHHHHHCHCT-CCC-E CS
         Roc  2 vvlvGdsgvGKtsllkrfvedkfsek 27
                +v++Gd+++GK+s l+ ++e  f +k
  EEA20736.1 61 IVVCGDQSAGKSSVLEALTEIPFPRK 86
                89***************999887666 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.8
                 TT-HHHHCT.SCEEEEEEEGHHHHCHHHHHHHHHHHCSSS.-EEEEEE- CS
         Roc  71 slhplylre.aalailvydsrssenlkeWlkelkkvagks.pvilvgnk 117
                 +++++y+++ + ++++v+ ++++   ++ l+++++  +k    + +++k
  EEA20736.1 208 EITESYISQpRTICLAVISATNDYANQPILNKVRQFDPKGeRTLGIITK 256
                 4677888761455666777777778889999999887764134445555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (760 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       798  (0.0445089); expected 358.6 (0.02)
Passed bias filter:                      564  (0.0314574); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.73u 0.31s 00:00:01.04 Elapsed: 00:00:00.48
# Mc/sec: 4776.32
//
Query:       EEA20737.1  [L=172]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.2e-29  101.7   0.1    3.6e-29  101.5   0.1    1.0  1  DUF3237   Protein of unknown function (DUF3237)


Domain annotation for each model (and alignments):
>> DUF3237  Protein of unknown function (DUF3237)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.5   0.1     2e-33   3.6e-29       1     149 []       4     168 ..       4     168 .. 0.91

  Alignments for each domain:
  == domain 1  score: 101.5 bits;  conditional E-value: 2e-33
                 --EEEEEEEEEEE--.-EEEEE...ETEEEEEEEEEEEEEES......TT--EEE-ST-EEEEEE-T.TS-EEEEEEEEEEETTS-EEEEEEEEEEE-- CS
     DUF3237   1 Pslepaftlevklea.pvpige...gpgkrnivpitgGtikg......prldgevlpgGaDwiridp.ggtarldaryvlktddgaliyirytGvvtld 88 
                 P+le+++tl+++ ++ +vp g+   gp  r++ p++gG ++g       +l+  + +gG+Dwi  dp +++a++d+r +  +  g+ +yi+ytG+++++
  EEA20737.1   4 PKLEHILTLRAYGTPiAVPAGKvrnGP-LRTCHPLEGGFLRGvdgtetEGLSVDLTSGGSDWISYDPsTNMAHVDVRTHGIDGAGDGFYISYTGYLRGE 101
                 99***********95336666677677.9999**********999988889999*************99****************************99 PP

                 GGGHHHHHHT-..---GGG-E...EEEEEEEEESSGGGGGGGSS-EEEEEEEESS.E...EEEEEEEE CS
     DUF3237  89 eevlavlgggekkesspteyg...frthptfetgdekykwLnnavfvGsgrfrve.g...veykvyev 149
                 e  ++ lg+ +++++ +t+yg   ++th  +et++ekyk L+++ +vG+gr+  + g   veyk ++v
  EEA20737.1 102 EIGQKFLGDWSAEVE-STNYGdhyWWTHAVIETSSEKYKSLTTTFLVGQGRWYAGeGkraVEYKLFKV 168
                 999999999885555.79999999*****************************7755789****9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (172 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       214  (0.011936); expected 358.6 (0.02)
Passed bias filter:                      172  (0.0095934); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.27s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 1199.97
//
Query:       EEA20738.1  [L=1151]
Description: ATP-binding cassette transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.2e-57  194.2  34.2    3.2e-57  194.2  34.2    2.5  1  SLAC1           Voltage-dependent anion channel
    1.7e-26   92.9  33.4    1.7e-26   92.9  33.4    3.8  1  ABC2_membrane   ABC-2 type transporter
    1.8e-25   90.0   0.1    3.1e-25   89.3   0.1    1.4  1  ABC_tran        ABC transporter
    8.6e-05   23.0   0.4    0.00024   21.6   0.1    1.8  2  AAA_16          AAA ATPase domain
    0.00012   22.1   0.0       0.26   11.1   0.0    2.2  2  AAA_21          AAA domain, putative AbiEii toxin, Type IV TA
    0.00023   20.7   0.1    0.00097   18.6   0.1    1.9  1  SMC_N           RecF/RecN/SMC N terminal domain
    0.00074   19.2   0.1     0.0015   18.2   0.1    1.4  1  AAA_25          AAA domain
    0.00083   19.1   0.1     0.0022   17.7   0.1    1.6  1  AAA_29          P-loop containing region of AAA domain
     0.0018   18.5   0.0     0.0039   17.5   0.0    1.6  1  AAA_22          AAA domain
     0.0019   18.2   0.1      0.006   16.5   0.1    1.9  2  RsgA_GTPase     RsgA GTPase
     0.0048   16.0   0.1     0.0082   15.2   0.1    1.3  1  T2SSE           Type II/IV secretion system protein
     0.0059   16.3   0.3      0.012   15.3   0.3    1.4  1  AAA_30          AAA domain
  ------ inclusion threshold ------
      0.015   15.8   0.2      0.034   14.7   0.2    1.5  1  AAA_23          AAA domain
      0.016   15.4   0.1      0.045   14.0   0.1    1.7  1  AAA_28          AAA domain
       0.02   14.7   0.0      0.036   13.8   0.0    1.4  1  IstB_IS21       IstB-like ATP binding protein
      0.023   14.6   0.1      0.053   13.4   0.1    1.6  1  NACHT           NACHT domain
      0.028   14.5   0.0      0.072   13.2   0.0    1.7  1  MMR_HSR1        50S ribosome-binding GTPase
      0.035   14.7   0.0      0.082   13.4   0.0    1.6  1  AAA_18          AAA domain
      0.037   14.5   0.0       0.14   12.6   0.0    1.9  2  AAA             ATPase family associated with various cellula
      0.073   13.2   0.1       0.14   12.3   0.1    1.4  1  AAA_33          AAA domain
      0.076   12.7   0.0       0.15   11.8   0.0    1.5  1  AAA_24          AAA domain
      0.077   12.9   0.1       0.14   12.0   0.1    1.4  1  NTPase_1        NTPase
      0.083   12.5   0.1       0.15   11.6   0.1    1.4  1  cobW            CobW/HypB/UreG, nucleotide-binding domain
      0.096   11.9   0.5       0.43    9.7   0.1    1.9  2  NB-ARC          NB-ARC domain
      0.096   12.6   0.0       0.63    9.9   0.0    2.1  2  ATPase_2        ATPase domain predominantly from Archaea
        0.1   12.3   0.1       0.19   11.5   0.1    1.4  1  Cytidylate_kin  Cytidylate kinase
       0.11   11.1   0.1       0.34    9.5   0.1    1.7  2  AAA_13          AAA domain
       0.12   11.2   0.3       0.21   10.4   0.0    1.5  2  AAA_35          AAA-like domain
       0.18   12.1   0.1       0.43   10.9   0.1    1.6  1  AAA_19          AAA domain


Domain annotation for each model (and alignments):
>> SLAC1  Voltage-dependent anion channel
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  194.2  34.2   5.2e-60   3.2e-57      31     324 .]      81     399 ..      61     399 .. 0.87

  Alignments for each domain:
  == domain 1  score: 194.2 bits;  conditional E-value: 5.2e-60
       SLAC1  31 islilfllalvlfllllvlyllrfilypeavrkelrhpveslflgtf..............pmglltilnglllvl.pgewlatlalvllW.igvllsl 113
                 i  ++ +la+  fl   +l+l  f+++ ++    l++p  ++ ++ +              +  ++++  +l+ v+  g+++ ++al+ +W ++++ls+
  EEA20738.1  81 IQRAMAILAVNCFLRTQCLVLPNFLWHIDSSLCPLSEPLSNNDYASYpvfvsrhtahglcnTYQYALL-VCLVCVPaWGQQAGYVALA-MWiVDAVLSV 177
                 67788888888888888888888888888888888887766666666343444444444332222222.2333344344889999999.9956****** PP

       SLAC1 114 ltavvvvfllftekee.kleeitpawllpvvgllvvallgallaes.qnpslqllgilvvslllwglGlllalvlfvlylyrlithklppaelrptlfi 210
                 +t+++++f+++t++++ kl +++ awllp  +++v+a++g+ +ae  +n++++l  ilv s++lwg+G+ la +++v+yl rl++hklpp+++++++f+
  EEA20738.1 178 FTCFGIIFIMITRRTKtKLGSMSVAWLLPSASCVVAAASGGIVAEVvPNSQIALE-ILVTSFILWGIGISLASMVIVIYLMRLMLHKLPPKAVIVSTFL 275
                 ************997779****************************999998998.******************************************* PP

       SLAC1 211 plGplgqgalallllgkaapk...........aaevlkvlalllalflwglglfwllvavlsvls...lpvrlkfslswWaftFPlgalalatielgka 295
                 pl p+g g++++++lg+ a+            a ++l+  + +++l++w++glfwl +av s+++   +p    f+lswWaftFPlg++a++t +lg++
  EEA20738.1 276 PLFPIGEGGFGIQKLGSVAKVilpqtdilpvaASDALYKTGNITGLLFWAFGLFWLSLAVGSIARvriFP----FNLSWWAFTFPLGVYATCTSQLGQE 370
                 *******************999**999999998899999**************************76666....************************* PP

       SLAC1 296 leseafkvlgtillvllvlvwllvlvgtl 324
                 ++s++f vlg+il++++vl+w+lv+++t+
  EEA20738.1 371 MPSKFFAVLGVILSIAVVLLWILVAIFTV 399
                 **************************996 PP

>> ABC2_membrane  ABC-2 type transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.9  33.4   2.8e-29   1.7e-26       5     210 .]     872    1079 ..     871    1079 .. 0.92

  Alignments for each domain:
  == domain 1  score: 92.9 bits;  conditional E-value: 2.8e-29
  ABC2_membrane    5 allkreflqrwrdpslgllwrliqplllalvfgtvfgnlg.nsedglnrpgllffsvlflafsaltsvapvferergvlerelvsplyslsayv 97  
                     +ll+r +++ +rd + +   r+i+ l la+++gtvf +   ++e ++ +++++ffs  f++f+a++ v p +  ++ ++++e+++++  + a++
     EEA20738.1  872 VLLQRAWIKSYRDIVAY-GIRIIMYLGLAILMGTVFLRFSpTQEYIQPYINAMFFSSAFMSFMAVAYV-PAYLEDQATFYKERANGIVGPLAFM 963 
                     79************999.99*****************988688888899************7777777.************************* PP

  ABC2_membrane   98 lakvlvelpvsllqalifllivyflvgldls.rfflfllllllt.alaasslgllisalapsfedasqlaslvllpllllsGffipidsmpkwl 189 
                     ++++++ lp+ +++a++f ++ y+l+g++ s  +f+ +l++l++ ++aa sl +l+s+++p f +a  ++ +v  +++ + Gf++pi+ + +++
     EEA20738.1  964 ISNFIIGLPFLFIIAFLFAVVEYWLTGFRASgTGFMTFLMWLFFdLVAAESLVVLVSSVFPVFVVALAVTAFVNGLWMCVNGFLVPITVLNSFW 1057
                     *******************************8556666666665166788****************************************7677 PP

  ABC2_membrane  190 qw.iaylnPltyavealrsnlf 210 
                     ++ ++y+ + +y+++++++n+f
     EEA20738.1 1058 KYvFHYIDYQAYVFQGMMVNEF 1079
                     776*****************97 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.3   0.1   5.1e-28   3.1e-25       3     137 .]     567     719 ..     565     719 .. 0.90

  Alignments for each domain:
  == domain 1  score: 89.3 bits;  conditional E-value: 5.1e-28
                 EEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--....SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH................HH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................xx RF
    ABC_tran   3 nvslklkegekvaivGenGaGKStLlkllagllkp....teGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren................es 81 
                 + +  +++ge++ai+G++G+GK+tLl+++a+ +      t G++l +g+     +l++ r  +++++q++ l   ltvre+                e+
  EEA20738.1 567 DTNGIVHAGEMIAIMGPSGSGKTTLLNAVAHRVAAagatTTGDLLANGQV---ANLQKIRDLSSYVEQDDALIGSLTVRETvgfaaglslpssvsksER 662
                 6677799**************************98666666666444433...4579**************************************9888 PP

                 HTCHHHHHHHSTTGGTTCBGESTTS.GGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  82 deeiekalsklglkelkdtvvkssp.ssLSgGqkqrvalarallkkpkllllDEpta 137
                 +++++ +++++gl++ ++t+v++   + LSgGqk+r+ ++  l+++pk+l+lDEpt+
  EEA20738.1 663 QRRVDSLIASFGLQDQAHTIVGTPIkKGLSGGQKKRLGVCSRLVTDPKILFLDEPTS 719
                 889******************888799****************************96 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.6   0.1   3.8e-07   0.00024      24      63 ..     575     613 ..     562     685 .. 0.74
   2 ?   -2.0   0.0       6.5     4e+03     109     153 ..     825     868 ..     793     877 .. 0.67

  Alignments for each domain:
  == domain 1  score: 21.6 bits;  conditional E-value: 3.8e-07
      AAA_16  24 pelvllsGesGvGKsslvrellralekdggiflrgkcdql 63 
                 +e++ + G+sG+GK++l++++++++ ++ g +++g+   +
  EEA20738.1 575 GEMIAIMGPSGSGKTTLLNAVAHRVAAA-GATTTGDLLAN 613
                 389********************99999.45555544444 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 6.5
      AAA_16 109 pelagaeasrllellkrllallsrderplvlvlDdlqwadeaslq 153
                 + l ++ea ++++++ +++a++++++   v  l d++  ++ s++
  EEA20738.1 825 KWLVSKEAASINQEIEDIIAKAKQPGT-SVPQLTDIHVQKPRSWA 868
                 445577889999999999999998665.55555555555555555 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.7   0.1    0.0022       1.4       3      19 ..     579     595 ..     577     623 .. 0.85
   2 !   11.1   0.0   0.00041      0.26     237     299 ..     691     751 ..     683     754 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0022
      AAA_21   3 vliGpNgsGKSnLLdal 19 
                 ++ Gp gsGK++LL a 
  EEA20738.1 579 AIMGPSGSGKTTLLNAV 595
                 789***********998 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00041
      AAA_21 237 lSdGtkrllalltallralkkgsllliDEpEngLHPkllrrllell.kelsrngaQviltTHSp 299
                 lS G+k+ l++ + l  ++   ++l++DEp +gL+  l  +++  + k+ ++n+  +i++ H+p
  EEA20738.1 691 LSGGQKKRLGVCSRLVTDP---KILFLDEPTSGLDSTLSFEVMNYIkKIGRENNLVIIASIHQP 751
                 6788888888888888877...9*************9999999999555555666666665665 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.1   1.6e-06   0.00097      24     200 ..     575     751 ..     563     767 .. 0.72

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 1.6e-06
                 SSEEEEEESTTSSHHHHHHHHHHHCTT.TTTTTTCHCCCCCC--BTTCSSTTEEEEEEEEEETTEESSSSSSCEEEEEEEETTSE.EEEEETTEEE-HH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxx RF
       SMC_N  24 ksftaivGpNGSGKsnlldAilFvLGersakklrseklsdlihkskekasvkkaeveitfdnedkklkiekeevsisrrvkrkge.seykingkevtkk 121
                  ++ ai+Gp GSGK+ ll+A+ +           ++++ dl+ +  + a+++k +    + ++d++      +++++ +v      s      k+ +++
  EEA20738.1 575 GEMIAIMGPSGSGKTTLLNAVAHRVAA-----AGATTTGDLLAN-GQVANLQKIRDLSSYVEQDDA---LIGSLTVRETVGFAAGlSLPSSVSKSERQR 664
                 56889****************988883.....3579999****9.677777766544445555554...234456666554433314445556667778 PP

                 HHHHHHHCTT-STT...........CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTT.SEEEEE-SSHH CS
                 xxxxxxxxxxxxxx...........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxx RF
       SMC_N 122 evsellesagiske...........lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkekskn.aQfivislree 200
                  v +l++s g++ +            LSgG+k+ + +  ++     +p+ + +lDe  + LD +   +v +++k+   +   +i+ s+++ 
  EEA20738.1 665 RVDSLIASFGLQDQahtivgtpikkGLSGGQKKRLGVCSRL---VTDPK-ILFLDEPTSGLDSTLSFEVMNYIKKIGREnNLVIIASIHQP 751
                 89999999999988899999999999*****9966655443...34455.6679********************87655155666666654 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.1   2.4e-06    0.0015      28      65 ..     570     608 ..     554     620 .. 0.85

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 2.4e-06
      AAA_25  28 gllpagelallaGapgtGKttlaldlalava.tGkpwlg 65 
                 g++ age ++++G++g+GKttl+  +a+ va  G   +g
  EEA20738.1 570 GIVHAGEMIAIMGPSGSGKTTLLNAVAHRVAaAGATTTG 608
                 7899***************************88877776 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.1   3.6e-06    0.0022      22      43 ..     574     596 ..     567     605 .. 0.85

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 3.6e-06
      AAA_29  22 kg.atlltGpsGsGKSTllDAiq 43 
                 +g ++ ++GpsGsGK+Tll A++
  EEA20738.1 574 AGeMIAIMGPSGSGKTTLLNAVA 596
                 455899**************986 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   0.0   6.4e-06    0.0039       6      31 ..     576     601 ..     572     749 .. 0.84

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 6.4e-06
      AAA_22   6 gilvvtGesGtGKTtllrrlleqlde 31 
                  +++++G+sG+GKTtll+ ++++  +
  EEA20738.1 576 EMIAIMGPSGSGKTTLLNAVAHRVAA 601
                 699*****************999743 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.1   9.8e-06     0.006      97     124 ..     573     600 ..     525     618 .. 0.73
   2 ?   -2.9   0.0         9   5.6e+03      18      39 ..     741     762 ..     736     768 .. 0.80

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 9.8e-06
                  CTTSEEEEECSTTSSHHHHHHHHCTT-- CS
  RsgA_GTPase  97 lkdktsvlvGqSGvGKStLinallpele 124
                   ++++++++G+SG GK+tL+na++ +  
   EEA20738.1 573 HAGEMIAIMGPSGSGKTTLLNAVAHRVA 600
                  35699*****************998754 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 9
                  EEEEEEESTTTT--HHHHHHHH CS
  RsgA_GTPase  18 qllivvslkepelslnlldrfL 39 
                  +l+i+ s+++p++ + +l   L
   EEA20738.1 741 NLVIIASIHQPSTATFMLFDKL 762
                  789********99998875554 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.1   1.3e-05    0.0082     126     155 ..     572     601 ..     546     607 .. 0.86

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1.3e-05
       T2SSE 126 vrerglilvsGgTgsGKttllyallkeink 155
                 v++  +i + G+ gsGKttll+a+ + +++
  EEA20738.1 572 VHAGEMIAIMGPSGSGKTTLLNAVAHRVAA 601
                 55678999****************999876 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.3     2e-05     0.012      17      51 ..     575     608 ..     569     648 .. 0.80

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 2e-05
      AAA_30  17 gdrvavltGpAGtGKttalkalreaweaaggrvig 51 
                 g  + ++ Gp G+GKtt+l+a+++ ++aag +  g
  EEA20738.1 575 G-EMIAIMGPSGSGKTTLLNAVAHRVAAAGATTTG 608
                 4.37899*****************99999966654 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   0.2   5.5e-05     0.034      21      39 ..     577     595 ..     569     609 .. 0.93

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 5.5e-05
      AAA_23  21 ltlItGpNGaGKTTildAi 39 
                 + +I Gp G+GKTT+l+A+
  EEA20738.1 577 MIAIMGPSGSGKTTLLNAV 595
                 679**************97 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.1   7.3e-05     0.045       2      22 ..     578     598 ..     577     624 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 7.3e-05
      AAA_28   2 ivitGgestGKTtlleaLaar 22 
                 i+i+G++++GKTtll+a a r
  EEA20738.1 578 IAIMGPSGSGKTTLLNAVAHR 598
                 89****************976 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   5.9e-05     0.036      43      77 ..     571     605 ..     540     631 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 5.9e-05
   IstB_IS21  43 fiekkenivllGpsGvGKshlaialgveavragls 77 
                  +++ e i+++GpsG GK+ l  a++++ ++ag  
  EEA20738.1 571 IVHAGEMIAIMGPSGSGKTTLLNAVAHRVAAAGAT 605
                 5788999********************99998875 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.1   8.6e-05     0.053       2      26 ..     577     601 ..     576     613 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 8.6e-05
                 CEEEEC-TTTCHHHHHHHHHHHHCT CS
       NACHT   2 lvilqGeaGsGKTtLlqklalawae 26 
                 ++++ G++GsGKTtLl  +a+  a+
  EEA20738.1 577 MIAIMGPSGSGKTTLLNAVAHRVAA 601
                 6899***************998876 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   0.00012     0.072       2      28 ..     578     604 ..     577     677 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 0.00012
                 EEEEESTTSSHHHHHHHHHTSTEEESS CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltgekaivsd 28 
                 +ai+G + +GK+tL+na   ++a +++
  EEA20738.1 578 IAIMGPSGSGKTTLLNAVAHRVAAAGA 604
                 89****************998665544 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   0.00013     0.082       1      30 [.     578     609 ..     578     641 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 0.00013
      AAA_18   1 IlltGtpGvGKttlakeLskrlgf..gvnlrd 30 
                 I+++G++G+GKttl ++++ r +    +  +d
  EEA20738.1 578 IAIMGPSGSGKTTLLNAVAHRVAAagATTTGD 609
                 89***************988852235333344 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   0.00022      0.14       3      28 ..     580     605 ..     578     644 .. 0.64
   2 ?   -2.4   0.0       9.5   5.9e+03      58      66 ..     708     716 ..     692     750 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 0.00022
                 EESSTTSSHHHHHHHHHHHHTHEEEE CS
         AAA   3 lyGppGtGKTllakavakelgvefle 28 
                 ++Gp G GKT+l +ava+ + +   +
  EEA20738.1 580 IMGPSGSGKTTLLNAVAHRVAAAGAT 605
                 78****************96443333 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 9.5
                 TSEEEEEET CS
         AAA  58 kpsilfiDE 66 
                 +p+ilf+DE
  EEA20738.1 708 DPKILFLDE 716
                 589999999 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.1   0.00022      0.14       2      95 ..     578     673 ..     577     685 .. 0.58

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00022
      AAA_33   2 vllvGlpGsGKstlaerllkklg..avllssdtlrr.rlfgtdqq.sktdytrvldrlyqilnelarkalsagrnvildatnlsrrerarflklarrl 95 
                 + + G++GsGK+tl+  ++ + +  + + + d l + ++++ ++  +++ y +  d l++ l  ++r++   ++++ l +   + ++++r+++l   +
  EEA20738.1 578 IAIMGPSGSGKTTLLNAVAHRVAaaGATTTGDLLANgQVANLQKIrDLSSYVEQDDALIGSL--TVRETVGFAAGLSLPSSVSKSERQRRVDSLIASF 673
                 6789************9987666666666666666645555333323444444444455555..4444444444444455555555555555555555 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   0.00024      0.15       4      22 ..     577     595 ..     574     634 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00024
      AAA_24   4 kiliyGpsgiGKTtlakel 22 
                 +i+i+Gpsg+GKTtl++  
  EEA20738.1 577 MIAIMGPSGSGKTTLLNAV 595
                 79*************9876 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.1   0.00023      0.14       2      32 ..     578     608 ..     577     618 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00023
                 EEEE--TTSSHHHHHHHHHHHH...GGGEEE CS
    NTPase_1   2 vfiTGppGvGKtTlvkkvlellkssgvkvgG 32 
                 ++i Gp+G+GKtTl++ v++ ++  g + +G
  EEA20738.1 578 IAIMGPSGSGKTTLLNAVAHRVAAAGATTTG 608
                 7899******************999998887 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.1   0.00025      0.15       3      22 ..     578     597 ..     576     610 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00025
                 EEEEESTTCCHHHHHHHHHC CS
        cobW   3 tvltGflGsGKTtLlnhlle 22 
                 + + G+ GsGKTtLln++ +
  EEA20738.1 578 IAIMGPSGSGKTTLLNAVAH 597
                 6799************9874 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.89   5.5e+02     110     130 ..     538     558 ..     535     564 .. 0.89
   2 ?    9.7   0.1    0.0007      0.43      22      43 ..     577     598 ..     570     629 .. 0.89

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.89
                 EEE-SHHHH.....HHHHCHT CS
      NB-ARC 110 DDVweeedwdkigvvlparen 130
                  DV+++  w+ki+v +++r  
  EEA20738.1 538 NDVVQNYAWRKINVQVKDRAT 558
                 6**************999875 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.0007
                 EEEEEESTTSSHHHHHHHHCCS CS
      NB-ARC  22 vvalvGmgGvGKttlakqilnk 43 
                 ++a++G  G+GKttl++ + + 
  EEA20738.1 577 MIAIMGPSGSGKTTLLNAVAHR 598
                 799*************999887 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0       1.6     1e+03     176     208 ..     439     471 ..     428     482 .. 0.80
   2 ?    9.9   0.0     0.001      0.63      21      44 ..     576     599 ..     571     607 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 1.6
    ATPase_2 176 neselegrhkyilvddldketalnflkegfkel 208
                 ++s  ++rh  +   +++ ++++n++++   ++
  EEA20738.1 439 ETSAYRQRHHCTFTLWMTGHQSWNLINFQLSQI 471
                 47888999*99****************988887 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.001
    ATPase_2  21 eiyfiYGpegsGKtaLlkeiienl 44 
                 e++ i Gp gsGKt+Ll+ ++ + 
  EEA20738.1 576 EMIAIMGPSGSGKTTLLNAVAHRV 599
                 57889*************998775 PP

>> Cytidylate_kin  Cytidylate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.1    0.0003      0.19       1      25 [.     578     602 ..     578     652 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.0003
                     EEEE-STTSSHHHHHHHHHHHHT-E CS
  Cytidylate_kin   1 iaiDGPagsGKssvaralaeklglk 25 
                     iai GP+gsGK ++  a+a+++ ++
      EEA20738.1 578 IAIMGPSGSGKTTLLNAVAHRVAAA 602
                     89******************98765 PP

>> AAA_13  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       1.5   9.5e+02      21      35 ..     580     594 ..     571     603 .. 0.84
   2 ?    9.5   0.1   0.00055      0.34     525     555 ..     707     737 ..     703     765 .. 0.85

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 1.5
      AAA_13  21 iYGwNGaGKTtLSrl 35 
                 i G  G+GKTtL ++
  EEA20738.1 580 IMGPSGSGKTTLLNA 594
                 77999******9665 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00055
      AAA_13 525 gkdkivviDDPvSSLDsnslfivfsliksrl 555
                 +  ki ++D P S LDs+ +f v+++ik+  
  EEA20738.1 707 TDPKILFLDEPTSGLDSTLSFEVMNYIKKIG 737
                 5789************************976 PP

>> AAA_35  AAA-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.1       7.2   4.4e+03     153     215 ..     413     480 ..     396     484 .. 0.60
   2 ?   10.4   0.0   0.00035      0.21      26      62 ..     570     606 ..     566     630 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 7.2
      AAA_35 153 LRswheeaknkeiwqkLrLvvvhs...tevyipldinqSpf...nvGl.pieLpeFtkeqvqeLaqrygl 215
                 L +w e+++++  ++k r+ +++s   te+    + ++  f    +G  +++L +F+ +q++ + q+++ 
  EEA20738.1 413 LAVWREKRRRE--LEKERFATIESgtgTETSAYRQRHHCTFtlwMTGHqSWNLINFQLSQITMVDQSQQK 480
                 56666655543..344444444444345555555555555522245642588999999999888777665 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00035
      AAA_35  26 eiekpGalirikapkkmGKtSLlarilakakqqgykt 62 
                  i ++G++i i +p+  GKt Ll+ + ++++++g  t
  EEA20738.1 570 GIVHAGEMIAIMGPSGSGKTTLLNAVAHRVAAAGATT 606
                 68899*********************99998887765 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.1    0.0007      0.43       8      38 ..     573     603 ..     568     632 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.0007
      AAA_19   8 lkekvllvtaGpGtGKTrvlkhivallvelg 38 
                 ++ ++++++++ G+GKT++l+++ + + ++g
  EEA20738.1 573 HAGEMIAIMGPSGSGKTTLLNAVAHRVAAAG 603
                 677899************9998877766655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1151 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1007  (0.056166); expected 358.6 (0.02)
Passed bias filter:                      481  (0.026828); expected 358.6 (0.02)
Passed Vit filter:                       109  (0.00607954); expected 17.9 (0.001)
Passed Fwd filter:                        30  (0.00167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              29  [number of targets reported over threshold]
# CPU time: 0.93u 0.31s 00:00:01.24 Elapsed: 00:00:00.46
# Mc/sec: 7549.90
//
Query:       EEA20739.1  [L=46]
Description: hypothetical protein PMAA_045620 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (46 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       279  (0.0155614); expected 358.6 (0.02)
Passed bias filter:                      263  (0.014669); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.28s 00:00:00.66 Elapsed: 00:00:00.44
# Mc/sec: 315.76
//
Query:       EEA20740.1  [L=1450]
Description: multidrug resistance-associated protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-48  164.7   0.0    1.1e-29  103.7   0.0    2.6  2  ABC_tran         ABC transporter
      7e-28   98.0  35.4      1e-20   74.5  16.8    2.8  2  ABC_membrane     ABC transporter transmembrane region
    1.9e-12   47.6   0.3    0.00096   19.0   0.1    4.4  4  AAA_21           AAA domain, putative AbiEii toxin, Type IV T
    6.3e-11   42.1   0.9      0.048   13.1   0.1    4.3  4  SMC_N            RecF/RecN/SMC N terminal domain
      1e-07   31.6   0.2     0.0093   15.7   0.0    2.7  2  AAA_29           P-loop containing region of AAA domain
    1.8e-07   31.7   0.3     0.0061   17.0   0.0    3.4  3  AAA_16           AAA ATPase domain
    4.8e-06   26.9   0.3      0.067   13.5   0.0    3.1  2  AAA_22           AAA domain
    2.3e-05   25.0   4.1     0.0048   17.4   0.0    3.3  3  AAA_23           AAA domain
    5.1e-05   23.3   0.0      0.071   13.2   0.0    2.8  2  MMR_HSR1         50S ribosome-binding GTPase
    6.6e-05   23.1   2.3    0.00031   20.9   0.5    2.6  3  DUF87            Helicase HerA, central domain
    7.8e-05   22.6   0.2       0.65    9.9   0.0    2.6  2  RsgA_GTPase      RsgA GTPase
    0.00031   20.2   0.0      0.039   13.3   0.0    2.4  2  FtsK_SpoIIIE     FtsK/SpoIIIE family
    0.00065   20.2   0.0          2    9.0   0.0    2.8  2  AAA_18           AAA domain
     0.0011   18.6   0.0      0.015   14.8   0.0    2.3  2  AAA_25           AAA domain
     0.0021   17.7   1.2          1    8.9   0.2    2.7  2  cobW             CobW/HypB/UreG, nucleotide-binding domain
     0.0022   18.2   0.0        1.5    9.0   0.0    3.0  2  AAA_33           AAA domain
     0.0024   17.0   0.1        1.9    7.5   0.0    2.5  2  T2SSE            Type II/IV secretion system protein
     0.0041   17.5   0.1        4.6    7.7   0.0    3.1  2  RNA_helicase     RNA helicase
     0.0044   17.1   0.1        1.2    9.2   0.0    2.6  2  Dynamin_N        Dynamin family
      0.008   16.1   0.4       0.16   11.8   0.0    2.3  2  dNK              Deoxynucleoside kinase
     0.0094   15.9   0.1       0.24   11.3   0.0    2.3  2  ATPase_2         ATPase domain predominantly from Archaea
     0.0097   15.8   0.2        4.4    7.2   0.0    2.8  2  NACHT            NACHT domain
  ------ inclusion threshold ------
       0.01   15.3   0.1       0.78    9.2   0.0    2.6  2  AAA_7            P-loop containing dynein motor region
      0.012   14.4   0.1       0.43    9.3   0.0    2.3  2  Adeno_IVa2       Adenovirus IVa2 protein
      0.012   15.3   0.0        6.4    6.4   0.0    2.6  2  AAA_15           AAA ATPase domain
      0.016   15.1   1.0        6.3    6.7   0.3    2.6  2  NTPase_1         NTPase
      0.026   13.5   0.3       0.12   11.3   0.0    2.0  2  MeaB             Methylmalonyl Co-A mutase-associated GTPase 
      0.034   14.2   0.0        1.6    8.8   0.0    2.3  2  TsaE             Threonylcarbamoyl adenosine biosynthesis pro
       0.04   13.8   0.7        0.2   11.6   0.1    2.3  2  Rad17            Rad17 P-loop domain
      0.043   13.6   0.1        1.8    8.2   0.0    2.7  2  Viral_helicase1  Viral (Superfamily 1) RNA helicase
      0.049   13.7   0.0       0.51   10.4   0.0    2.6  2  AAA_14           AAA domain
      0.075   13.0   0.1        9.4    6.2   0.0    3.2  3  AAA_5            AAA domain (dynein-related subfamily)
        0.1   12.3   0.1        6.6    6.4   0.0    2.6  2  AAA_24           AAA domain
        0.1   13.0   0.2        6.4    7.2   0.1    3.7  3  AAA              ATPase family associated with various cellul
       0.11   11.4   0.3        1.5    7.6   0.0    2.3  2  TrwB_AAD_bind    Type IV secretion-system coupling protein DN
       0.14   11.3   0.1        2.6    7.1   0.0    2.2  2  DUF815           Protein of unknown function (DUF815)
       0.18   11.0   0.6         28    3.8   0.0    3.1  3  KAP_NTPase       KAP family P-loop domain


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.4   0.0   2.2e-18   1.1e-15       7     136 ..     631     760 ..     627     761 .. 0.84
   2 !  103.7   0.0   2.2e-32   1.1e-29       1     137 []    1220    1367 ..    1220    1367 .. 0.92

  Alignments for each domain:
  == domain 1  score: 58.4 bits;  conditional E-value: 2.2e-18
                 EEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH..........HHHTC...HHHHHHHS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..........xxxxx...xxxxxxxx RF
    ABC_tran   7 klkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren..........esdee...iekalskl 92 
                  l +g+ ++i+G+ G+GKSt+lk+l+ ++   +G+             + + ++i+++ q+p + +++ +r+n          +++     +e  l+  
  EEA20740.1 631 RLPRGSFTVITGPIGCGKSTFLKCLLSETAFVQGTA------------PTSPENIAYCNQTPWIHDGT-IRDNivgeskfdlsWYKHVirsCELELDLG 716
                 6889*******************************8............8899*************999.*****9988877773333312233333333 PP

                 TTGGTTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  93 glkelkdtvvksspssLSgGqkqrvalarallkkpkllllDEpt 136
                 ++++ + + v+s++  LSgGq+qr+++aral  k+++ ++D+ t
  EEA20740.1 717 RITGGDSSMVGSRGLRLSGGQRQRISIARALYAKKDIAIFDDVT 760
                 33446789999999***************************988 PP

  == domain 2  score: 103.7 bits;  conditional E-value: 2.2e-32
                  EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH........HHHTCHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxx RF
    ABC_tran    1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren........esdeeiekal 89  
                  l+++sl++k+ge v+i G++G+GKS+L+++l++ll+  +G+il+dg d+++ + + +r+++  ++qep+l +++ vren         sde i ++l
  EEA20740.1 1220 LSDISLSIKPGEHVGICGRTGSGKSSLVSTLLRLLECSQGHILIDGVDISTLDPNLVRSRLNLITQEPFLYEGS-VRENatpwqhdtVSDESIIDVL 1315
                  689**********************************************************************9.*******9999888888***** PP

                  HHSTTGGTTCBGESTTS....GGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                  xxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran   90 sklglkelkdtvvkssp....ssLSgGqkqrvalarallkkpkllllDEpta 137 
                  ++++l ++ ++  + ++    + +S+Gq+q  +larall+++++l+lDEpt+
  EEA20740.1 1316 TRVDLWDKIKSLGGLDApfkeNLISHGQQQLFCLARALLRESNILILDEPTS 1367
                  *******55555444445665889**************************96 PP

>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.3  10.6   2.6e-09   1.2e-06       1     272 [.     273     552 ..     273     554 .. 0.77
   2 !   74.5  16.8   2.2e-23     1e-20       4     267 ..     886    1147 ..     884    1155 .. 0.88

  Alignments for each domain:
  == domain 1  score: 28.3 bits;  conditional E-value: 2.6e-09
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHHHHSCH CS
  ABC_membrane   1 liliillailagvlsplfplvlgrildtlldkgdpetealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsffdtnsv 97 
                   l++i+++  +  +l+++ p++ ++ + +l +  ++   +   ++  ++ + ++ ++++  + ++   +++ ++ +l  +++ k+l+  ++  d+   
    EEA20740.1 273 LFFIFMSRTMEVGLNIVYPFLVQKAVTFLDTPTTTIN-DGYGLLGGFFCVSVGIALVSPWSYHMTFRLMIMTRGALIPMIYSKLLQTKVKPADQS-- 366
                   5778888888888999999999998888854333333.455555555555555555555555555889999****************99988875.. PP

                   HHHHHHHHHHHHHHHHHHCHHHHH.HHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHH CS
  ABC_membrane  98 Gellsrltndvsklrdglgeklgl.ffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirtV 193
                      l+++t+dv+k+ + +++ +++ ++  l++ ++++++++ lg  + +v ++++++++ + av ++++ +++++  kav+ + +++  ++s ++ V
    EEA20740.1 367 -AALTLMTTDVEKIVETFWRLILDpWSCILQLGICVYLLYLQLGA-VCCVPIIVIFVCFGLVAVASRRVPEYQNTWFKAVESRVNLTSHTISSMQSV 461
                   .66899*******9887777766549999999*********9999.5799999999999999*********************************** PP

                   HHTTTHHHHHHHHHHHHHHHHHHHHH.......HHHHHHHHHHHHH.....HHHHHHHHHHHHHHHHHHHTTSSTHHHHHHHHHHHHHHHH CS
  ABC_membrane 194 kafgreeyflekfekaleeakkagik.......kaianglligitq.....llgllsyalalwfGttlvisgelsvgdlvvflslfailfg 272
                   k++g  +++++ ++k+++++ + +         +++a  + ++++q     +l+ l++++++ +   l+++g+ +v+++v+ ls+++++++
    EEA20740.1 462 KLLGISRIMETTIQKKRKQEIQVSQDfrfnnclALTACTIHFSFSQpqspaVLSPLLTFATYAIVKLLSHQGQFDVSKAVTSLSILSLMNT 552
                   ****************999888764311111114444445555554444445677777788888888888888888888888888887776 PP

  == domain 2  score: 74.5 bits;  conditional E-value: 2.2e-23
                    HHHHHHHHHHHHHHHHHHHHHHHHHHHSSTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHHHHHHHHHCSTHHHHHHSCH CS
  ABC_membrane    4 iillailagvlsplfplvlgrildtlldkgdpetealnvysllllllglaqfilallqsyll.nvtgerlskrlrrklfkkilrqpmsffdtnsv 97  
                     + l +l+ +++++f  +++ ++ +  ++   +  +l +++ l++  g++ +++ l+   ++ +++  + s +l+++l+ + lr+pm f+++ ++
    EEA20740.1  886 NFALFLLGAIIYVVFYAFFQIWITWWAEDTAGRH-TLGYWLGLYATWGVLITLALLFTPLFFfYYMVPKSSEKLHSELLAAALRAPMLFISKLDT 979 
                    678999********************99744444.588888888888877777777666655489****************************** PP

                    HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHH CS
  ABC_membrane   98 GellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirt 192 
                    G+l++r++ d++  ++ l+ +++l +  +l +++++++++ +  ++++ +  +  ++++++ ++ +++++l+  e ++ a++ s+++++++g+ t
    EEA20740.1  980 GSLVNRFSQDIRLSDWQLPVTIVLTLFEFLGCIASVGIAVSSVKYVAIGIPLLGSVLYFLQRFYLRTSRQLRLLEIESKAPLVSLFIDTIQGLAT 1074
                    ************99999****************************************************************************** PP

                    HHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSTHHHHHHHHHHH CS
  ABC_membrane  193 VkafgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttlvisgelsvgdlvvflslf 267 
                    ++afg+ ++f++k    l+  +k  +    ++++l  ++ l++ ++ +l++ +  +  ++  ++ g +   ++  
    EEA20740.1 1075 IRAFGWSQAFVQKSLSLLDVSQKPFYLLFSVQRWLLLVLSLVVAALEVLVMGI--AIPLRTSVNAGLVGLAIVQV 1147
                    *******************************************9999999544..44444445555544444444 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.4   0.0    0.0017      0.85       1      20 [.     637     656 ..     637     700 .. 0.86
   2 ?    5.4   0.0     0.028        14     246     301 ..     742     798 ..     731     800 .. 0.75
   3 !    8.2   0.0    0.0041         2       3      56 ..    1234    1285 ..    1233    1327 .. 0.65
   4 !   19.0   0.1     2e-06   0.00096     229     278 ..    1331    1381 ..    1302    1396 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0017
      AAA_21   1 lnvliGpNgsGKSnLLdald 20 
                 ++v++Gp g+GKS++L++l 
  EEA20740.1 637 FTVITGPIGCGKSTFLKCLL 656
                 89****************93 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.028
      AAA_21 246 alltallralkkgsllliDEpEngLHPkllrrll.ell...kelsrngaQviltTHSpll 301
                  ++ al++  kk ++ ++D++ + L+ + lr +  +++     l+++g+ v+l+TH   l
  EEA20740.1 742 SIARALYA--KK-DIAIFDDVTSALDARTLRAVSnRVFgkdGVLRSKGTTVVLATHAVQL 798
                 44444554..33.9********************7777977666669*********7665 PP

  == domain 3  score: 8.2 bits;  conditional E-value: 0.0041
      AAA_21    3 vliGpNgsGKSnLLdaldllarldrdvegltdelsggggirkipslldlydpei 56  
                  ++ G+ gsGKS+L  +l  l    +++ +  ++  ++++++    +++l+ +++
  EEA20740.1 1234 GICGRTGSGKSSLVSTLLRLL--ECSQGHILIDGVDISTLDPNLVRSRLNLITQ 1285
                  689**************9998..5566665555555555555555555555444 PP

  == domain 4  score: 19.0 bits;  conditional E-value: 2e-06
      AAA_21  229 gqelparelSdGtkrllalltallralkkgsllliDEpEngLHP....kllrrl 278 
                  + ++  + +S G+++l++l+ allr      +l++DEp ++++P     ++r +
  EEA20740.1 1331 DAPFKENLISHGQQQLFCLARALLRES---NILILDEPTSHIDPatdaTIQRII 1381
                  556666777****************99...89************6663333333 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   0.0    0.0037       1.8      24      44 ..     635     655 ..     625     668 .. 0.83
   2 !   10.6   0.0   0.00056      0.27     136     209 ..     732     806 ..     687     813 .. 0.77
   3 ?    5.5   0.0     0.021        10      26      46 ..    1232    1252 ..    1219    1262 .. 0.80
   4 !   13.1   0.1   9.9e-05     0.048     132     208 ..    1334    1406 ..    1302    1413 .. 0.87

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0037
                 SSEEEEEESTTSSHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  24 ksftaivGpNGSGKsnlldAi 44 
                  sft+i+Gp G+GKs +l  +
  EEA20740.1 635 GSFTVITGPIGCGKSTFLKCL 655
                 57**************99877 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00056
                 CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHH.....HHCTTSEEEEE-SSHHHCCC-SCEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 136 lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellk.....eksknaQfivislreemlekadklv 209
                  LSgG+++ +++a       + ++ + ++D++ +aLD++  ++v++++       +sk + ++  ++  ++l+ ad+++
  EEA20740.1 732 RLSGGQRQRISIAR----ALYAKKDIAIFDDVTSALDARTLRAVSNRVFgkdgvLRSKGTTVVLATHAVQLLQSADQVM 806
                 69****99887764....3466677889*****************9986333333566677777888888888887776 PP

  == domain 3  score: 5.5 bits;  conditional E-value: 0.021
                  EEEEEESTTSSHHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxx RF
       SMC_N   26 ftaivGpNGSGKsnlldAilF 46  
                  +  i G+ GSGKs+l+  +l 
  EEA20740.1 1232 HVGICGRTGSGKSSLVSTLLR 1252
                  5679***********998865 PP

  == domain 4  score: 13.1 bits;  conditional E-value: 9.9e-05
                  -STTCS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC-SCE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  132 iskelLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQfivislreemlekadkl 208 
                  ++++l+S G+++L  la        + + + +lDe  +++D +  + + ++++e+ +n  +i+i++r + l + d++
  EEA20740.1 1334 FKENLISHGQQQLFCLA----RALLRESNILILDEPTSHIDPATDATIQRIIREDFQNRTVIMIAHRLQSLVDFDRV 1406
                  56668999999997765....45689999**************************************9988777766 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   1.9e-05    0.0093      13      39 ..     626     652 ..     624     658 .. 0.82
   2 !   13.0   0.1   0.00013     0.063      17      50 ..    1225    1258 ..    1218    1261 .. 0.82

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 1.9e-05
      AAA_29  13 dghtieidlkgatlltGpsGsGKSTll 39 
                 + ++i++ + ++t++tGp+G GKST+l
  EEA20740.1 626 SLQDIRLPRGSFTVITGPIGCGKSTFL 652
                 55778887555**************98 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 0.00013
      AAA_29   17 ieidlkgatlltGpsGsGKSTllDAiqalLvpak 50  
                  ++i++ + + + G++GsGKS+l+  +  lL +++
  EEA20740.1 1225 LSIKPGEHVGICGRTGSGKSSLVSTLLRLLECSQ 1258
                  6677777889*************99999987766 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0   1.3e-05    0.0061      17      70 ..     628     679 ..     625     768 .. 0.85
   2 ?   -0.8   0.1       3.6   1.8e+03     116     158 ..    1030    1092 ..     957    1104 .. 0.63
   3 !   10.6   0.0    0.0012      0.56      25      56 ..    1231    1262 ..    1217    1423 .. 0.76

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 1.3e-05
      AAA_16  17 ervrsgrpelvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipy...s 70 
                 +++r +r++ ++++G+ G+GKs+ +++ll      +  f++g++  ++++i+y    
  EEA20740.1 628 QDIRLPRGSFTVITGPIGCGKSTFLKCLLS-----ETAFVQGTAPTSPENIAYcnqT 679
                 5667778899*******************6.....4679999999999999995533 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 3.6
      AAA_16  116 a.........srllellkrllallsrderp..lvlvlDdlq.........wadeaslqllaaL 158 
                  +         +r++   +r l+ll+ +++   + l++D +q         w ++  ++ l++L
  EEA20740.1 1030 PllgsvlyflQRFYLRTSRQLRLLEIESKAplVSLFIDTIQglatirafgWSQAFVQKSLSLL 1092
                  244444456678888888888888887664578899999998888877776666555555444 PP

  == domain 3  score: 10.6 bits;  conditional E-value: 0.0012
      AAA_16   25 elvllsGesGvGKsslvrellralekdggifl 56  
                  e v + G  G+GKsslv +llr le + g+ l
  EEA20740.1 1231 EHVGICGRTGSGKSSLVSTLLRLLECSQGHIL 1262
                  778899***************98877755553 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.0   0.00014     0.067       5      29 ..     635     659 ..     631     680 .. 0.78
   2 !    9.8   0.0    0.0018      0.88       8      30 ..    1233    1255 ..    1227    1289 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 0.00014
      AAA_22   5 agilvvtGesGtGKTtllrrlleql 29 
                  +++v+tG+ G+GK+t l+ ll++ 
  EEA20740.1 635 GSFTVITGPIGCGKSTFLKCLLSET 659
                 689*****************99986 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.0018
      AAA_22    8 lvvtGesGtGKTtllrrlleqld 30  
                  + ++G +G+GK+ l+ +ll+ l+
  EEA20740.1 1233 VGICGRTGSGKSSLVSTLLRLLE 1255
                  569***************99985 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.0   9.8e-06    0.0048      13      40 ..     628     656 ..     623     863 .. 0.80
   2 ?    7.4   0.1     0.012       5.7      23      36 ..    1234    1247 ..    1220    1254 .. 0.86
   3 ?   -1.8   0.0       7.7   3.7e+03     108     143 ..    1311    1350 ..    1288    1387 .. 0.75

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 9.8e-06
      AAA_23  13 qeidF.skgltlItGpNGaGKTTildAik 40 
                 q+i +    +t+ItGp G+GK+T+l ++ 
  EEA20740.1 628 QDIRLpRGSFTVITGPIGCGKSTFLKCLL 656
                 5666644469*****************96 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.012
      AAA_23   23 lItGpNGaGKTTil 36  
                   I+G +G+GK++++
  EEA20740.1 1234 GICGRTGSGKSSLV 1247
                  7***********97 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 7.7
      AAA_23  108 klelleideleqfisellgskkiilnlilflgqer....f 143 
                  + + l+  +l+++i++l g + +  ++++ +gq++    +
  EEA20740.1 1311 IIDVLTRVDLWDKIKSLGGLDAPFKENLISHGQQQlfclA 1350
                  4444555889999999999999999999999999966651 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.0     0.012       5.7       3      32 ..     639     668 ..     637     682 .. 0.86
   2 !   13.2   0.0   0.00015     0.071       1      41 [.    1232    1278 ..    1232    1315 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.012
                 EEEESTTSSHHHHHHHHHTSTEEESSSTTS CS
    MMR_HSR1   3 aivGrpNvGKStLinaltgekaivsdkpgt 32 
                 +i G    GKSt+++ l+ e+a v+ ++ t
  EEA20740.1 639 VITGPIGCGKSTFLKCLLSETAFVQGTAPT 668
                 7999***************99999877665 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 0.00015
                  EEEEEESTTSSHHHHHHHHHT.....S.TEEESSSTTSSSSEEEEEE CS
    MMR_HSR1    1 evaivGrpNvGKStLinaltg.....e.kaivsdkpgtTrdinegrv 41  
                  +v+i Gr+ +GKS+L+++l++     + +  +      T+d+n  r 
  EEA20740.1 1232 HVGICGRTGSGKSSLVSTLLRllecsQgHILIDGVDISTLDPNLVRS 1278
                  599****************9855553245677777788888877665 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.1       1.4   6.7e+02      33      48 ..     645     660 ..     639     665 .. 0.85
   2 ?   -2.6   0.0       9.7   4.7e+03     171     222 ..    1173    1222 ..    1164    1227 .. 0.73
   3 !   20.9   0.5   6.4e-07   0.00031      24      57 ..    1231    1263 ..    1216    1265 .. 0.84

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 1.4
       DUF87  33 GsGKSntvavLleell 48 
                 G GKS++ + Ll+e +
  EEA20740.1 645 GCGKSTFLKCLLSETA 660
                 99**********9975 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 9.7
       DUF87  171 kledllrkggsfsnsstdliallleklekegkitiidlsgvdelaqqlvvsv 222 
                  +++++++++       td +++l+++  ++g++t +++s   e + ++  s 
  EEA20740.1 1173 RISRFIKETPRE--GRTDETSSLFDEWPSSGAVTLVNVSASYEPQGNQALSD 1222
                  556666666666..6677778888888999********99888777666555 PP

  == domain 3  score: 20.9 bits;  conditional E-value: 6.4e-07
       DUF87   24 rHlAilgsTGsGKSntvavLleellekkgatili 57  
                  +H++i g+TGsGKS +v+ Ll+ l    +++ili
  EEA20740.1 1231 EHVGICGRTGSGKSSLVSTLLRLLE-CSQGHILI 1263
                  8********************9876.66777766 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.9   0.0    0.0014      0.65      98     124 ..     634     660 ..     600     672 .. 0.85
   2 !    9.8   0.1    0.0014      0.68      87     123 ..    1217    1254 ..    1201    1263 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.0014
                  TTSEEEEECSTTSSHHHHHHHHCTT-- CS
  RsgA_GTPase  98 kdktsvlvGqSGvGKStLinallpele 124
                  +++++v+ G+ G GKSt+++ ll+e+ 
   EEA20740.1 634 RGSFTVITGPIGCGKSTFLKCLLSETA 660
                  56899*****************99854 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.0014
                   HTTHHHHHHHCTT.SEEEEECSTTSSHHHHHHHHCTT- CS
  RsgA_GTPase   87 kegleelkellkd.ktsvlvGqSGvGKStLinallpel 123 
                   +++l++++  +k  + + ++G +G GKS+L+ +ll  l
   EEA20740.1 1217 NQALSDISLSIKPgEHVGICGRTGSGKSSLVSTLLRLL 1254
                   566777777888768889**************998755 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0     0.055        27      32      63 ..     626     659 ..     596     665 .. 0.67
   2 !   13.3   0.0   8.1e-05     0.039      36      60 ..    1228    1251 ..    1210    1255 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.055
                   EEEGGGS-...SEEEE--TTSSHHHHHHHHHHHH CS
  FtsK_SpoIIIE  32 vldlkkma..shllvaGatgsGKStalntLilSl 63 
                    l+ +  +  s +++ G  g GKSt+l+ L+   
    EEA20740.1 626 SLQDIRLPrgSFTVITGPIGCGKSTFLKCLLSET 659
                   44445555777899**************998655 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 8.1e-05
                    GGS-.SEEEE--TTSSHHHHHHHHH CS
  FtsK_SpoIIIE   36 kkmashllvaGatgsGKStalntLi 60  
                    k+ + h+ ++G+tgsGKS  + tL+
    EEA20740.1 1228 KPGE-HVGICGRTGSGKSSLVSTLL 1251
                    4455.******************97 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.0   0.0    0.0041         2       2      22 ..     639     659 ..     639     695 .. 0.83
   2 !    8.0   0.0    0.0081       3.9       1      30 [.    1233    1264 ..    1233    1304 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.0041
      AAA_18   2 lltGtpGvGKttlakeLskrl 22 
                 ++tG++G+GK+t+ k L +++
  EEA20740.1 639 VITGPIGCGKSTFLKCLLSET 659
                 59***********99886554 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0081
      AAA_18    1 IlltGtpGvGKttlakeLskrlgf..gvnlrd 30  
                  ++++G  G+GK++l   L ++l++  g +l+d
  EEA20740.1 1233 VGICGRTGSGKSSLVSTLLRLLECsqGHILID 1264
                  78****************99998888544444 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   3.2e-05     0.015      25      61 ..     627     665 ..     605     675 .. 0.80
   2 ?    0.7   0.0      0.71   3.4e+02      33      53 ..    1230    1250 ..    1224    1262 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 3.2e-05
      AAA_25  25 lvkgllpagelallaGapgtGKttlaldlalava..tGk 61 
                 l +  lp+g++++++G+ g+GK+t++  l  ++a  +G 
  EEA20740.1 627 LQDIRLPRGSFTVITGPIGCGKSTFLKCLLSETAfvQGT 665
                 555579********************9999998866654 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.71
      AAA_25   33 gelallaGapgtGKttlaldl 53  
                  ge + ++G++g+GK+ l++ l
  EEA20740.1 1230 GEHVGICGRTGSGKSSLVSTL 1250
                  5666689**********9877 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.9   0.2    0.0021         1       2      23 ..     637     658 ..     636     665 .. 0.87
   2 !    6.8   0.0    0.0097       4.7       3      34 ..    1233    1264 ..    1231    1285 .. 0.71

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0021
                 EEEEEESTTCCHHHHHHHHHCT CS
        cobW   2 vtvltGflGsGKTtLlnhllen 23 
                  tv+tG++G GK+t+l+ ll++
  EEA20740.1 637 FTVITGPIGCGKSTFLKCLLSE 658
                 58***************99965 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.0097
                  EEEEESTTCCHHHHHHHHHCT--SS-EEEEES CS
        cobW    3 tvltGflGsGKTtLlnhllenraglklavivN 34  
                  ++++G  GsGK++L+++ll+  +  +  +++ 
  EEA20740.1 1233 VGICGRTGSGKSSLVSTLLRLLECSQGHILID 1264
                  5799***************6666555555555 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.0   0.0     0.003       1.5       3      52 ..     639     706 ..     638     717 .. 0.76
   2 ?    5.7   0.0     0.033        16       4      24 ..    1235    1255 ..    1233    1321 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.003
      AAA_33   3 llvGlpGsGKstlaerllkklgavllssdt..................lrrrlfgtdqqsktdytrvl 52 
                 ++ G+ G+GKst+++ ll ++++v  + +t                  +r++++g+ + ++++y++v 
  EEA20740.1 639 VITGPIGCGKSTFLKCLLSETAFVQGTAPTspeniaycnqtpwihdgtIRDNIVGESKFDLSWYKHVI 706
                 578***************99998877777766677777777777777666677777776777777765 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.033
      AAA_33    4 lvGlpGsGKstlaerllkklg 24  
                  ++G  GsGKs l+  ll+ l 
  EEA20740.1 1235 ICGRTGSGKSSLVSTLLRLLE 1255
                  79*************998766 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.7   0.0    0.0067       3.2     131     152 ..     637     658 ..     596     663 .. 0.83
   2 !    7.5   0.0     0.004       1.9     126     162 ..    1227    1263 ..    1200    1285 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0067
       T2SSE 131 lilvsGgTgsGKttllyallke 152
                   +++G+ g GK+t+l  ll+e
  EEA20740.1 637 FTVITGPIGCGKSTFLKCLLSE 658
                 4589*************99987 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.004
       T2SSE  126 vrerglilvsGgTgsGKttllyallkeinksderivt 162 
                  ++    + + G TgsGK+ l+ +ll  ++ s+ +i++
  EEA20740.1 1227 IKPGEHVGICGRTGSGKSSLVSTLLRLLECSQGHILI 1263
                  5555666689******************999888765 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.7   0.0    0.0095       4.6       2      23 ..     639     660 ..     638     692 .. 0.68
   2 ?    6.1   0.0     0.029        14       3      23 ..    1235    1255 ..    1233    1270 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0095
  RNA_helicase   2 wlyGpsgeGKStlakeLakall 23 
                   +++Gp g+GKSt+ k L ++ +
    EEA20740.1 639 VITGPIGCGKSTFLKCLLSETA 660
                   689************9988766 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.029
  RNA_helicase    3 lyGpsgeGKStlakeLakall 23  
                    ++G++g GKS+l+ +L + l+
    EEA20740.1 1235 ICGRTGSGKSSLVSTLLRLLE 1255
                    89*************988776 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.2   0.0    0.0025       1.2       2      32 ..     639     669 ..     638     712 .. 0.90
   2 ?    5.2   0.1     0.042        20       1      19 [.    1233    1251 ..    1233    1275 .. 0.92

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0025
                 EEEEBTTTTHHHHHHHHHTS--S---SSS-- CS
   Dynamin_N   2 avvGsqSsGKSSvlnaLlgedilprgpnptT 32 
                 ++ G    GKS++l  Ll e  ++ g+ pt+
  EEA20740.1 639 VITGPIGCGKSTFLKCLLSETAFVQGTAPTS 669
                 688999*********************9986 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.042
                  EEEEEBTTTTHHHHHHHHH CS
   Dynamin_N    1 iavvGsqSsGKSSvlnaLl 19  
                  + ++G + sGKSS++  Ll
  EEA20740.1 1233 VGICGRTGSGKSSLVSTLL 1251
                  679************9998 PP

>> dNK  Deoxynucleoside kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   0.0   0.00032      0.16       2      24 ..     639     661 ..     638     677 .. 0.83
   2 ?    1.9   0.1      0.36   1.7e+02       3      23 ..    1235    1255 ..    1233    1266 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00032
                 EEEESTTSSHHHHHHHHHCCSTC CS
         dNK   2 vveGnIgaGKstlvklLskklgv 24 
                 v+ G+Ig+GKst++k L  ++ +
  EEA20740.1 639 VITGPIGCGKSTFLKCLLSETAF 661
                 799************77666554 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.36
                  EEESTTSSHHHHHHHHHCCST CS
         dNK    3 veGnIgaGKstlvklLskklg 23  
                  + G  g+GKs+lv++L + l+
  EEA20740.1 1235 ICGRTGSGKSSLVSTLLRLLE 1255
                  66999*********9987776 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.3   0.0   0.00049      0.24      21      42 ..     636     657 ..     630     664 .. 0.86
   2 ?    1.8   0.0       0.4     2e+02      23      45 ..    1233    1255 ..    1222    1266 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00049
    ATPase_2  21 eiyfiYGpegsGKtaLlkeiie 42 
                 ++ +i+Gp+g+GK+++lk +++
  EEA20740.1 636 SFTVITGPIGCGKSTFLKCLLS 657
                 689**************98766 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.4
    ATPase_2   23 yfiYGpegsGKtaLlkeiienle 45  
                  + i G+ gsGK++L+  ++  le
  EEA20740.1 1233 VGICGRTGSGKSSLVSTLLRLLE 1255
                  5689***********99887775 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.2   0.0    0.0091       4.4       3      24 ..     638     659 ..     636     667 .. 0.87
   2 ?    5.8   0.0     0.025        12       5      28 ..    1235    1258 ..    1231    1262 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0091
                 EEEEC-TTTCHHHHHHHHHHHH CS
       NACHT   3 vilqGeaGsGKTtLlqklalaw 24 
                  +++G+ G+GK+t+l+ l ++ 
  EEA20740.1 638 TVITGPIGCGKSTFLKCLLSET 659
                 689************9998765 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.025
                  EEC-TTTCHHHHHHHHHHHHCTS- CS
       NACHT    5 lqGeaGsGKTtLlqklalawaegk 28  
                  + G+ GsGK+ L+  l +++  ++
  EEA20740.1 1235 ICGRTGSGKSSLVSTLLRLLECSQ 1258
                  78**************99998765 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0      0.14        67      34      56 ..     636     658 ..     625     669 .. 0.83
   2 ?    9.2   0.0    0.0016      0.78      28      58 ..    1225    1255 ..    1219    1265 .. 0.86

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.14
       AAA_7  34 kpvllvGptGtGKtviikdllkk 56 
                   ++++Gp G+GK++ +k ll++
  EEA20740.1 636 SFTVITGPIGCGKSTFLKCLLSE 658
                 55789***********9998876 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.0016
       AAA_7   28 lllknkkpvllvGptGtGKtviikdllkkld 58  
                  l +k + +v ++G tG+GK++++++ll+ l+
  EEA20740.1 1225 LSIKPGEHVGICGRTGSGKSSLVSTLLRLLE 1255
                  6688899******************999876 PP

>> Adeno_IVa2  Adenovirus IVa2 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.0    0.0009      0.43      90     111 ..     638     659 ..     589     676 .. 0.86
   2 ?    2.5   0.1      0.11        51      77     108 ..    1219    1251 ..    1205    1258 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.0009
  Adeno_IVa2  90 GviyGPtGsGksqllrnlissk 111
                  vi GP G+Gks +l+ l+s  
  EEA20740.1 638 TVITGPIGCGKSTFLKCLLSET 659
                 69*****************964 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.11
  Adeno_IVa2   77 elsslnyglqPviGv.iyGPtGsGksqllrnli 108 
                   ls + +  +P   v i G tGsGks l+ +l+
  EEA20740.1 1219 ALSDISLSIKPGEHVgICGRTGSGKSSLVSTLL 1251
                  566666666664443378**********99987 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.0     0.013       6.4      14      43 ..     627     655 ..     626     696 .. 0.87
   2 ?    5.6   0.0     0.022        11      14      69 ..    1220    1272 ..    1218    1298 .. 0.75

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.013
      AAA_15  14 lkdveidlseeltvliGkNnsGKSsileal 43 
                 l+d+ ++  + +tv+ G+ ++GKS++l+ l
  EEA20740.1 627 LQDIRLPRGS-FTVITGPIGCGKSTFLKCL 655
                 6777777777.****************998 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.022
      AAA_15   14 lkdveidlsee.ltvliGkNnsGKSsilealdlFlnnkekknkkvikiekedleife 69  
                  l+d+++++++     ++G+ +sGKSs++  l  +l+ +    +  i i+  d+++ +
  EEA20740.1 1220 LSDISLSIKPGeHVGICGRTGSGKSSLVSTLLRLLECS----QGHILIDGVDISTLD 1272
                  5666666666666779***************9999877....455566665555555 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   0.3     0.013       6.3       3      20 ..     639     656 ..     638     665 .. 0.86
   2 ?    6.2   0.0     0.018       8.8       1      26 [.    1232    1257 ..    1232    1278 .. 0.86

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.013
                 EEE--TTSSHHHHHHHHH CS
    NTPase_1   3 fiTGppGvGKtTlvkkvl 20 
                 +iTGp G GK+T++k +l
  EEA20740.1 639 VITGPIGCGKSTFLKCLL 656
                 79***********98766 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.018
                  EEEEE--TTSSHHHHHHHHHHHH... CS
    NTPase_1    1 kvfiTGppGvGKtTlvkkvlellkss 26  
                  +v i G+ G+GK+ lv+ +l+ll+ s
  EEA20740.1 1232 HVGICGRTGSGKSSLVSTLLRLLECS 1257
                  789******************99755 PP

>> MeaB  Methylmalonyl Co-A mutase-associated GTPase MeaB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0       1.2   5.7e+02      34      50 ..     640     656 ..     630     662 .. 0.83
   2 ?   11.3   0.0   0.00025      0.12       4      54 ..    1202    1255 ..    1200    1274 .. 0.81

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 1.2
                 EEE-TTSSHHHHHHHHH CS
        MeaB  34 ltGvPGaGkstlvealg 50 
                 +tG  G Gkst+++ l 
  EEA20740.1 640 ITGPIGCGKSTFLKCLL 656
                 89**********98775 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00025
                  HHHHHH--SH...HHHHHHHHHGGG-S-SEEEEEEE-TTSSHHHHHHHHHHHHH CS
        MeaB    4 aitlveserp...eakellerllakaGraqvvGltGvPGaGkstlvealglelr 54  
                  a+tlv+ + +   + ++ l+ ++ +    + vG+ G  G+Gks lv+ l   l 
  EEA20740.1 1202 AVTLVNVSASyepQGNQALSDISLSIKPGEHVGICGRTGSGKSSLVSTLLRLLE 1255
                  7888875544444999********9999********************988775 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   0.0    0.0032       1.6      19      52 ..     635     668 ..     606     676 .. 0.79
   2 ?    2.7   0.0      0.25   1.2e+02      19      45 ..    1230    1256 ..    1213    1262 .. 0.78

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0032
                 TEEEEEEESTTSSHHHHHHHHHHHTT------TT CS
        TsaE  19 gdvilLeGdLGaGKTtlvrglakalgveevkSPT 52 
                 g++ +++G++G+GK+t+ + l+++  + + + PT
  EEA20740.1 635 GSFTVITGPIGCGKSTFLKCLLSETAFVQGTAPT 668
                 556899***************9998765444444 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.25
                  TEEEEEEESTTSSHHHHHHHHHHHTT- CS
        TsaE   19 gdvilLeGdLGaGKTtlvrglakalgv 45  
                  g+ + + G  G+GK+ lv  l++ l++
  EEA20740.1 1230 GEHVGICGRTGSGKSSLVSTLLRLLEC 1256
                  6678899***************99876 PP

>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.1   0.00041       0.2      48      68 ..     638     658 ..     627     679 .. 0.84
   2 ?   -0.9   0.1       2.7   1.3e+03      35      69 ..    1220    1254 ..    1216    1266 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00041
       Rad17  48 LLisGPsGCgkstvvkvLske 68 
                  +i+GP GCgkst +k L  e
  EEA20740.1 638 TVITGPIGCGKSTFLKCLLSE 658
                 579*************98655 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 2.7
       Rad17   35 lkadvLesrkkriLLisGPsGCgkstvvkvLskel 69  
                  l   +L  ++ + + i+G +G gks  v  L + l
  EEA20740.1 1220 LSDISLSIKPGEHVGICGRTGSGKSSLVSTLLRLL 1254
                  5556666666777789*********9999886655 PP

>> Viral_helicase1  Viral (Superfamily 1) RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   0.0    0.0038       1.8       2      22 ..     639     659 ..     638     683 .. 0.81
   2 ?    2.2   0.0      0.26   1.3e+02       5      21 ..    1237    1253 ..    1235    1285 .. 0.78

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0038
  Viral_helicase1   2 vvhGvpGcGKStlirkllrts 22 
                      v+ G  GcGKSt ++ ll++ 
       EEA20740.1 639 VITGPIGCGKSTFLKCLLSET 659
                      888889************984 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.26
  Viral_helicase1    5 GvpGcGKStlirkllrt 21  
                       G  G+GKS+l+ +llr 
       EEA20740.1 1237 GRTGSGKSSLVSTLLRL 1253
                       668************98 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0     0.001      0.51       4      37 ..     637     677 ..     634     681 .. 0.86
   2 ?   -0.9   0.0       3.3   1.6e+03       5      35 ..    1233    1262 ..    1230    1290 .. 0.72

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.001
      AAA_14   4 ilvitGaRrvGKTtllkqlikell.......vkkesilyin 37 
                   vitG+  +GK+t+lk l++e         +++e+i y n
  EEA20740.1 637 FTVITGPIGCGKSTFLKCLLSETAfvqgtapTSPENIAYCN 677
                 679****************9998888888888888888876 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 3.3
      AAA_14    5 lvitGaRrvGKTtllkqlikellvkkesily 35  
                  + i G   +GK+ l+ +l++ l   ++  + 
  EEA20740.1 1233 VGICGRTGSGKSSLVSTLLRLLE-CSQGHIL 1262
                  567788899*******9996665.4444444 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0      0.26   1.3e+02       3      40 ..     639     672 ..     638     686 .. 0.75
   2 ?   -1.6   0.0         5   2.4e+03      62      79 ..     746     765 ..     723     814 .. 0.68
   3 ?    6.2   0.0     0.019       9.4       4      26 ..    1235    1257 ..    1232    1264 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.26
                 EEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHH CS
       AAA_5   3 lLvGppGtgKselaerlaaalnreveyvqltrdtteed 40 
                 ++ Gp G+gKs++ + l++    e+  vq+t+ t++e+
  EEA20740.1 639 VITGPIGCGKSTFLKCLLS----ETAFVQGTAPTSPEN 672
                 679********99877664....555566666665555 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 5
                 ---.G-SEEEEESGGG--.H CS
       AAA_5  62 aar.egeilvlDEverae.s 79 
                 a   +++i+++D+v+ a   
  EEA20740.1 746 ALYaKKDIAIFDDVTSALdA 765
                 33358999999999977633 PP

  == domain 3  score: 6.2 bits;  conditional E-value: 0.019
                  EE--SSSSHHHHHHHGGGGBS-- CS
       AAA_5    4 LvGppGtgKselaerlaaalnre 26  
                  + G +G+gKs+l+  l+++l+++
  EEA20740.1 1235 ICGRTGSGKSSLVSTLLRLLECS 1257
                  78*****************9554 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.0     0.014       6.6       6      29 ..     639     662 ..     635     682 .. 0.89
   2 ?    2.8   0.0      0.17        84       5      27 ..    1233    1254 ..    1230    1275 .. 0.81

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.014
      AAA_24   6 liyGpsgiGKTtlakelgpkplfi 29 
                 +i+Gp g GK+t++k l  +++f+
  EEA20740.1 639 VITGPIGCGKSTFLKCLLSETAFV 662
                 89**************98888887 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.17
      AAA_24    5 iliyGpsgiGKTtlakelgpkpl 27  
                  + i G  g+GK++l+++l  + l
  EEA20740.1 1233 VGICGRTGSGKSSLVSTL-LRLL 1254
                  6799*************9.5444 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   0.1     0.013       6.4       3      22 ..     640     659 ..     638     812 .. 0.74
   2 ?   -1.5   0.0       6.6   3.2e+03      52      74 ..    1054    1076 ..    1038    1099 .. 0.73
   3 ?    0.2   0.0       1.9   9.1e+02       3      22 ..    1235    1254 ..    1233    1285 .. 0.73

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.013
                 EESSTTSSHHHHHHHHHHHH CS
         AAA   3 lyGppGtGKTllakavakel 22 
                 ++Gp G+GK+++ k + +e+
  EEA20740.1 640 ITGPIGCGKSTFLKCLLSET 659
                 79*************99995 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 6.6
                  HHHHTSTS.EEEEEETGGGHHHHH CS
         AAA   52 eakekakp.silfiDEidalaksr 74  
                  e+++ka p + lfiD i  la+ r
  EEA20740.1 1054 EIESKA-PlVSLFIDTIQGLATIR 1076
                  456676.7788*********9999 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 1.9
                  EESSTTSSHHHHHHHHHHHH CS
         AAA    3 lyGppGtGKTllakavakel 22  
                  ++G  G GK++l++ + + l
  EEA20740.1 1235 ICGRTGSGKSSLVSTLLRLL 1254
                  57889999999998887765 PP

>> TrwB_AAD_bind  Type IV secretion-system coupling protein DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.1      0.37   1.8e+02      18      38 ..     638     658 ..     634     664 .. 0.90
   2 ?    7.6   0.0    0.0031       1.5      16      47 ..    1231    1262 ..    1220    1267 .. 0.84

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.37
  TrwB_AAD_bind  18 ilivGttGsGKtqalekllra 38 
                    ++i+G +G GK++ l+ ll +
     EEA20740.1 638 TVITGPIGCGKSTFLKCLLSE 658
                    78**************99975 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0031
  TrwB_AAD_bind   16 qhilivGttGsGKtqalekllrairargdrai 47  
                     +h+ i G tGsGK+  ++ llr ++  +  ++
     EEA20740.1 1231 EHVGICGRTGSGKSSLVSTLLRLLECSQGHIL 1262
                     69*******************98876655544 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.0      0.29   1.4e+02      57      77 ..     639     659 ..     635     663 .. 0.88
   2 ?    7.1   0.0    0.0053       2.6      51      78 ..    1228    1255 ..    1217    1278 .. 0.82

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.29
      DUF815  57 LLwGarGtGKSslvkallney 77 
                 +++G  G+GKS+ +k ll+e+
  EEA20740.1 639 VITGPIGCGKSTFLKCLLSET 659
                 578999***********9986 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0053
      DUF815   51 lpannvLLwGarGtGKSslvkallneya 78  
                  +p ++v + G  G+GKSslv +ll+ ++
  EEA20740.1 1228 KPGEHVGICGRTGSGKSSLVSTLLRLLE 1255
                  67899999*************9987654 PP

>> KAP_NTPase  KAP family P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0     0.058        28      18      44 ..     633     659 ..     626     691 .. 0.75
   2 ?   -2.4   0.7       4.4   2.2e+03      19      31 ..     921     933 ..     917     933 .. 0.86
   3 ?    3.7   0.0     0.063        31      18      47 ..    1228    1257 ..    1215    1345 .. 0.86

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.058
  KAP_NTPase  18 atpivvgLygkWGsGKssllnkledel 44 
                  +++  +++g+ G+GKs++l+ l +e 
  EEA20740.1 633 PRGSFTVITGPIGCGKSTFLKCLLSET 659
                 566677899999*********998875 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 4.4
  KAP_NTPase  19 tpivvgLygkWGs 31 
                  ++ +gLy+ WG+
  EEA20740.1 921 LGYWLGLYATWGV 933
                 68899*******7 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.063
  KAP_NTPase   18 atpivvgLygkWGsGKssllnkledelkef 47  
                  +++  vg+ g  GsGKssl+  l + l+  
  EEA20740.1 1228 KPGEHVGICGRTGSGKSSLVSTLLRLLECS 1257
                  777889999***********9999888766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1450 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       867  (0.0483574); expected 358.6 (0.02)
Passed bias filter:                      495  (0.0276089); expected 358.6 (0.02)
Passed Vit filter:                        91  (0.00507558); expected 17.9 (0.001)
Passed Fwd filter:                        38  (0.00211947); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              37  [number of targets reported over threshold]
# CPU time: 1.10u 0.33s 00:00:01.43 Elapsed: 00:00:00.51
# Mc/sec: 8574.91
//
Query:       EEA20741.1  [L=3154]
Description: polyketide synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.6e-98  329.7   0.0    5.3e-98  329.1   0.0    1.2  1  Carn_acyltransf  Choline/Carnitine o-acyltransferase
    9.5e-71  238.3   0.0    2.1e-70  237.2   0.0    1.7  1  ketoacyl-synt    Beta-ketoacyl synthase, N-terminal domain
    1.2e-55  189.2   0.1    2.4e-55  188.3   0.1    1.5  1  Acyl_transf_1    Acyl transferase domain
    2.8e-50  170.7   0.1      1e-49  168.9   0.1    2.1  1  KR               KR domain
    4.9e-38  131.1   0.1    8.6e-38  130.2   0.1    1.4  1  PS-DH            Polyketide synthase dehydratase
    1.3e-20   73.6   0.6    5.5e-16   58.6   0.0    3.2  3  Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
    4.4e-18   66.6   0.0    2.7e-16   60.8   0.0    3.1  2  ADH_zinc_N_2     Zinc-binding dehydrogenase
      7e-17   62.0   0.0    3.8e-16   59.6   0.0    2.5  1  Methyltransf_12  Methyltransferase domain
    1.2e-16   60.9   0.1    7.2e-16   58.4   0.0    2.4  2  ADH_zinc_N       Zinc-binding dehydrogenase
    1.8e-14   54.1   0.0    4.4e-14   52.9   0.0    1.7  1  KAsynt_C_assoc   Ketoacyl-synthetase C-terminal extension
    2.9e-12   46.4   0.0    2.6e-11   43.3   0.1    2.5  2  adh_short        short chain dehydrogenase
    1.6e-10   41.6   0.0    2.4e-09   37.8   0.0    3.2  1  Methyltransf_25  Methyltransferase domain
    4.9e-10   39.9   0.0    7.1e-09   36.2   0.0    2.8  2  Methyltransf_11  Methyltransferase domain
    4.4e-09   36.3   0.0    1.3e-08   34.8   0.0    1.8  1  Methyltransf_31  Methyltransferase domain
    6.6e-07   29.6   0.0    1.7e-06   28.3   0.0    1.7  1  PP-binding       Phosphopantetheine attachment site
    7.4e-07   29.0   0.0    2.4e-06   27.3   0.0    1.9  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    1.1e-06   28.2   0.0    6.6e-06   25.6   0.0    2.2  2  Ubie_methyltran  ubiE/COQ5 methyltransferase family
    3.5e-06   27.0   0.0    1.1e-05   25.4   0.0    1.8  1  Methyltransf_23  Methyltransferase domain
  ------ inclusion threshold ------
       0.01   15.9   0.0      0.037   14.1   0.0    2.0  1  DUF4113          Domain of unknown function (DUF4113)
       0.15   11.4   0.0       0.28   10.5   0.0    1.4  1  Rtf2             Rtf2 RING-finger


Domain annotation for each model (and alignments):
>> Carn_acyltransf  Choline/Carnitine o-acyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  329.1   0.0  5.9e-101   5.3e-98       4     584 ..    2575    3144 ..    2573    3147 .. 0.88

  Alignments for each domain:
  == domain 1  score: 329.1 bits;  conditional E-value: 5.9e-101
                       -----HHHHHHHHHHHHHCCSHHHHHHHHHHHHHHHHC...THHHHHHHHHHHHHSSHT-STTTHHHHHHHHTTT--S-HHHHTBEEEE-GC CS
  Carn_acyltransf    4 LPvPkLedTleryleslkpllseeelekteklveeflk...geGpkLqerLraekekktsknwledwWedyaYleyrdplvlnsnpfllled 92  
                        P+P+L+d l+ ++++  +l+s+e+l+++++ ++ +++      + +qe L++++++k+s+ w +d+  d+ +l++r p+ ++ ++++++ d
       EEA20741.1 2575 QPLPDLDDALDFWISTTGHLYSPEQLQTVQQDIQTIKApdsPARRAFQELLKTHEHEKMSNGWYNDVLSDARWLSKRYPVAPYQSIMVTHRD 2666
                       6***********************************9988556678899997777777999************************7774444 PP

                       CCCTSTCHHHHHHHHHHHHHHHHHHHHHHTT-S--TE.EETEE---GGGGGSSSEEEE--SSS-EEEEE--TSS---EEEEEETTEEEEEEC CS
  Carn_acyltransf   93 dpdpkeknqqlkraAklilsalkfkkllrreelepdvikkgkplcmsqykrlfnttRiPgkekDklvkykkedkesrhivVlrkgqfYkvdv 184 
                       ++   + + q++raA + +s+ +f+++++++++ep +i +gkp c + +++lfn++R P+  +Dk+++y++     +hi+Vlrkg+++kv +
       EEA20741.1 2667 SK---RLQSQAERAAIISSSVFSFNRAMKAGKIEPFWI-AGKPSCTWRWDWLFNSVREPHIGCDKMMRYDD----CNHIAVLRKGHVFKVML 2750
                       44...455555*************************98.59***************************976....89**************9 PP

                       ECECTTEE--HHHHHHHHHHHHHHHHCCG.----GGGGGGS-HHHHHHHHHHHCC-TCHHHHHHHHHHCSS-EEEE----SS---HCCHHHH CS
  Carn_acyltransf  185 leddggrllspaelekqleeIlsdsekeesaeepvgvlTtenRdewakareellksekkNkeslelIesalfvvcLDdespededeeelakq 276 
                          d+g+ ++ ++le+++e+I+++  +   ++   g+lTt++R++wa +re+l++s+ +N+e +++Iesa+fv+cLDd  pe+ +  e+a+q
       EEA20741.1 2751 Q--DHGEDMPLEKLEATFEAIITQVGD---DALWTGILTTDERNSWAMVREKLSSSSLTNAEYFRVIESAMFVLCLDDGFPETPE--ERARQ 2835
                       8..555889*************43323...479*********************98777*********************84444..6**** PP

                       HHCTTCGC--TTBSEEEEE-TTS-EEEEE-STT--HHHHHHHHHHHHHCCHCTTTT--S----S-SSS....-EEE-----HHHHHHHHHHH CS
  Carn_acyltransf  277 llhgsgtnRWfDKslqlivtknGkaglnfEHswaDgtvvlrlvedvltdsilkeakekneeksssseeslpepeklefkldeelkeaieeae 368 
                          g+g+nRWfDK lq+ v++nG++gl+ EH ++Dgt+ +rl e++ +++ +  +++++   + ++    ++ e++  + + e++++i+  +
       EEA20741.1 2836 GYIGDGSNRWFDKVLQFTVSENGRSGLITEHGGVDGTTSARLSEWIAKAIDEYLPRNIH---HYEN----IQLEEVVLESTVEVDSHIDILK 2920
                       **************************************************999998862...3333....45899***************** PP

                       HHHHHHHCCEEEEEEEETS--HHHHCCCT--HHHHHHHHHHHHHHHHHSS---EEEEEE-TTSTT--EEEEE---HHHHHHHHHHHS..... CS
  Carn_acyltransf  369 trldklisdldlkvlefkeyGksfikkfklspDafiQmalQlAyyrlygklaatyEsastrkFrhGRtEtirsvteeslafvkamds..... 455 
                       +r+++ +s   +   +++e+G++f+ + k+    ++ + +QlA    yg+  + +Es+s++ +++GRtE ++ +  +++ f+ a  +     
       EEA20741.1 2921 RRFRENTSAGTYMRETLTEFGTDFLVQGKMPVKQVVDITFQLAVRLFYGRNIPSWESISVAYYHQGRTESVQRALAAVVSFCDAAAKaynge 3012
                       ************************************************************************************85556666 PP

                       ....SCTHCCHH........HHHHHHHHHHHHHHHHHHTTTSSHHHHHHHHHHHHHT...--HH..SS.-HHHHSHHHHHCT--SEEEEE.. CS
  Carn_acyltransf  456 ....kasdeekl........ellrkAvkahskltkeaakGkGvdrHLfaLkllakel...eseg..eelpelFkdplykklnnwrLsTSqls 530 
                           +      +        +ll   +k+ +++++e  +G+   r +  L  ++ +       +  +    lF+   + +++++ L T  + 
       EEA20741.1 3013 dgigA------TpvdtvklaALLSTSTKQMNANMQEILNGRSHIRVMELLNWVWPSDaaiP--KprSLSEGLFHGRPSVYAQSNALETDMV- 3095
                       66642......033333456**********************************9865332..1323334888888888899999999995. PP

                       .SSSEEEES--SSTT-EEEEEEEETC.EEEEEEETCTTS--HHHHHHHHHHHHH CS
  Carn_acyltransf  531 spalkgfGfgpvvpdGyGigYiikddsisfvisskkksetsserfaeaLeeale 584 
                          ++ f     +p+G++   +++++si+++++    s+++++ f+++L++a+ 
       EEA20741.1 3096 ---IDDFVSLLPNPEGFWTIMMPEKNSIRLSLTGG--SQERTTAFSKQLHRAAG 3144
                       ...6666677779*********************4..3579*********9975 PP

>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  237.2   0.0   2.4e-73   2.1e-70       2     253 .]       5     256 ..       4     256 .. 0.96

  Alignments for each domain:
  == domain 1  score: 237.2 bits;  conditional E-value: 2.4e-73
                    --EEEEEEEEEBTTBSS.HHHHHHHHHTT---EEES-TTSSCGTTSBTSSTTEEE-BSS.EEE..S..TTEGGTTSTHHHHHHHCTS-HHHHHHHH CS
  ketoacyl-synt   2 epvaivGmgarfPggnd.veefwelLlegrdaiselpadrwdadklydpparaagkiktklggfld..vddfdpeffgispreaeamdpqqrllle 94 
                    +++a++Gm++r+Pgg + +e++w++L egrd+ +e+p+drwd++ +y++++++++ ++ ++g+f+d  v++fd +ffgi++ ea+ +dpqqr++le
     EEA20741.1   5 RQIAVIGMACRLPGGAEnPESLWSMLAEGRDGWQEVPKDRWDWKSFYHKDPETKEAMNFSHGYFIDqdVSAFDTQFFGIPAAEATGVDPQQRIALE 100
                    78***********99888****************************************************************************** PP

                    HHHHHHHHHTS-HHTCTTGGEEEEEEESSTHHHHHHHHHHHTTGGGSCTTHHHHHSTTHHHHHHHHHHT--SSEEEEESGGGHHHHHHHHHHHHHH CS
  ketoacyl-synt  95 aawealedagltpeeldgsrvgvfiGvgagdyaalaaldedgsevkaspkavgavlanviagrisyalglrGpsvtvdtACsSslvavhaavqslr 190
                     ++ea+e+ag++ e+l+gs++ v +++ a+dy+ +   d ++ + ka  +++ga   +++++risy ++l+G s t+dt Cs slva+h+a++ l+
     EEA20741.1 101 LTYEAFEHAGIPIETLRGSDTSVHMAMFARDYDRMGYKDGPQ-IHKA--HILGA-GDAILSNRISYVFDLKGSSNTLDTGCSGSLVALHQACRTLK 192
                    ********************************8877777666.3444..56888.99*************************************** PP

                    TTS-SEEEEEEEE---SHHHHHHHHHTT.BB-TTSGGGTTBTTB-SB-BB-EEEEEEEEECHHH CS
  ketoacyl-synt 191 sgeadvalaGGvellltpeavagfsaag.llspdgrckafdpkadGfvlGEGvGavvLkrleda 253
                    +gea +a+aG+++l+ltp + +++ + g l+++dgr+ +fd++++G+ +GEGvG++vLk l++a
     EEA20741.1 193 DGEATLAVAGASQLMLTPDQSIAMTSVGtLINKDGRSYTFDDRGSGYGRGEGVGVLVLKCLDQA 256
                    ****************************999999*************************99887 PP

>> Acyl_transf_1  Acyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  188.3   0.1   2.7e-58   2.4e-55       2     313 ..     536     863 ..     535     868 .. 0.87

  Alignments for each domain:
  == domain 1  score: 188.3 bits;  conditional E-value: 2.7e-58
                    EEE--TT---TTTTCCHHHC-HHHHHHHHHHHHHCCHH.HT--HHHHHHS--T.TGGGSHHHHHHHHHHHHHHHHHHHHHTT-TTSEEEE-TTHHH CS
  Acyl_transf_1   2 fvfsGqGsQwaGMGmeLlktskafaaviaradeafksq.ygfsvldvlrnnpe.glldaiqfvqpaLaavqialaellkskGvrpaavvGHSlGEl 95 
                    +vf+GqG+Qw +MG+eLl+ts++f  +i  +++ +k    ++ +   l + +e + + +  f+qp ++a+qial++ll+ +G++p++v GHS GE+
     EEA20741.1 536 YVFTGQGAQWFAMGRELLATSQVFVTSIMLCNQILKGLgCDWELGSELSQPQEsSRVGDSRFSQPCMTAIQIALVDLLENFGLQPETVCGHSSGEI 631
                    9***********************************84379***88888876537888999*********************************** PP

                    HHHHHCCSSSHHHHHHHHHHHHHHHHHHT....S-EECCEECS...HHHHHHH....TT.EEEEEEECCCCECCEEHHHHHHHHHHHHHCC.CCEE CS
  Acyl_transf_1  96 Aaavvagalsseeallavvlrsrlmmqla....gpgdmaavel..aeeeeklr..cqddvvgavansprrvvisgsqealrelvervskegvgalv 183
                    Aaa++agals e a+ a++ r+ +   ++     +g+m+av++  +++++++r  ++ ++++a++nsp++++isg  +a++el + +   +v+ ++
     EEA20741.1 632 AAAYAAGALSREAAMEAAYYRGICSSMAKglnpTNGAMLAVGEgvEAITPRIRniTTGRLTVACVNSPESTTISGDVAAIEELQAVLDSVTVFNRR 727
                    **********9888888877765544433222569********9989999999767899************************************* PP

                    ECCCEECTTCCCCCCCCHHHHHHHHCCCHHCH..HTTBEHCCCHHHHHHCHHHHHHHHHHHCHCCHCCHHTTS...SSECC..-CCEECSSSSCCH CS
  Acyl_transf_1 184 envnvavhspqvdaiadalasaladiaprkpk..vakisstsldesserelsaeywvanlrspvrfaeavlsa...aetip..lvfveispHslll 272
                     +v+ a hs  ++ +a+  +s l ++a+  p+  va++ss++   +    +   ywv nl s v+f +a + +   ++ ip  +++vei pH+ l 
     EEA20741.1 728 LVVDSAYHSHHMEVVAKSHLSSLEHMAHGIPRtnVAFYSSVTGTRK-LSDFGPSYWVSNLLSQVKFSAASQLVaehLAAIPgaNIIVEIGPHAALS 822
                    *************************999888644788888876655.568999*************999876645555555116789********* PP

                    CCCCCCCHHGGG-T.CCCCCCTEETTSS-HHHCHHHHHHHHH CS
  Acyl_transf_1 273 aalektlksaedvk.satlvGklkrdltdflvtflyllakah 313
                      l++tl   ++ + ++t +++l+r+ ++ + t l+l++k +
     EEA20741.1 823 GPLRQTLSHISNSSfKYTYIPTLIRNRNA-VDTILALAGKTF 863
                    ********977765489**********99.888888877765 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  168.9   0.1   1.1e-52     1e-49       1     178 [.    2165    2344 ..    2165    2346 .. 0.92

  Alignments for each domain:
  == domain 1  score: 168.9 bits;  conditional E-value: 1.1e-52
                  SEEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------T CS
          KR    1 gtylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdkll 97  
                  gty+i GGlG LG+ ++++laekga h+v lsR++   ++ ++l +++++ g + ++v++D++d+++++a+ +ei+ + pp++G+i+ A vl d++l
  EEA20741.1 2165 GTYVIGGGLGDLGRRMSHFLAEKGAGHIVTLSRRNIDIQQRSSLEESIKKIGSTLHIVKCDITDEESMRAAATEIS-QLPPVRGIIQGALVLYDHPL 2260
                  8*********************************87777888888999***************************8.779***************** PP

                  TT--HHHHHHHHTTTTHHHHHHHHHTTT.S--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHHHH..HTEEEEEE--B CS
          KR   98 eemtaedleqvlapKvkGawnLhelled.esldffvlfSSiagllgsagqanYaaaNaflDalaeyrrsqg..lpavsinwglw 178 
                  e m+ ed+ ++l+pKv+G+ n+h+ll + ++ dff+++SS+a+++g++ q+nY+a+N+f+Da+a+ ++++   ++ ++in g++
  EEA20741.1 2261 EYMNVEDWMTALKPKVQGTLNMHKLLCSpKTTDFFIMLSSVASIVGATSQSNYSAGNSFQDAFAHAQQATSslTKYTTINVGAV 2344
                  ************************87655************************************9987651145678888776 PP

>> PS-DH  Polyketide synthase dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  130.2   0.1   9.6e-41   8.6e-38       1     293 [.     920    1225 ..     920    1230 .. 0.84

  Alignments for each domain:
  == domain 1  score: 130.2 bits;  conditional E-value: 9.6e-41
                  BTTB..-EE--.-SS-EEEEEEE-S-SS.TTTSEEETTEEB--TTHHHHHHHHHHHHTS---.......-EEEEEEEE----.B--SS.-EEEEEEE CS
       PS-DH    1 hpllG.srvrsasdkevvfrnrlrlaelpwLrDHrvdgkvvlPgagylemaleAarqltges......kavelrdvsilkalvlpede.pvevqlsl 89  
                  h+l+G   v s + +e+++r  ++l++ pwL+DH+v+g v++Pga+yl m+ eA++ql++        k++ +rd+s++k +v++e++   e+ql++
  EEA20741.1  920 HDLVGlFDVFS-ALHEPRWRYIVSLQSIPWLQDHVVEGFVIFPGAAYLTMVTEAMKQLFQLRrtlgriKSINFRDISFKKSVVISESKgDDELQLTI 1015
                  77777334444.699********************************************877888999***************************** PP

                  EE-TTS-E....EEEEEEE-SS-TT.EEEEEEEEEE-------B--HHHHHHHS-SEE....E-..HHHHHHHHHHHSEEE-GGG--EEEEEEETTE CS
       PS-DH   90 epeedgadrawvefeifSregggeewtehatGtvrlaegaaaaavdlealqarcaepaslrsvs..saefYerlaargleyGpsFqglralwrgdge 184 
                   p+++++++ w  f++ S++ +++ wteh tG v++ ++a+  ++++++++ +++++ +++++    +e+ +  ++  + + p F g+ ++++g+  
  EEA20741.1 1016 SPARQHDASPWEYFRVLSYDPENDSWTEHTTGLVTTVTEAQ--DLQADEVEGTREDDLFTEDALriLQEIQTNSSHPVMILAPVF-GVARIHVGKCC 1109
                  ***87777***************99**********887766..788888877777777655544333444444445558899**9.9********** PP

                  EEEEE---GGGSSTTTT....-SB-HHHHHHHHHHG..GG----------EEEEEEEEEEE-S....-BTS--EEEEEE----SS-EEEEEEEE-.. CS
       PS-DH  185 alaelrlpeelaggesa....yvlhPallDaalQllaaalsaeaekadaaylPvaierlrvyr.pssaageelwvharleeegarsivadltlvd.. 274 
                   la++ + + +++  ++    +++hP++lDa+ Ql+aa++  ++e + a+++Pv +++l+++  +++++g+el v   l  eg r++ +   +++  
  EEA20741.1 1110 GLAKVVVENIVQKMPGQymqpHLIHPTTLDAVNQLQAAVF--RRECSIAPVMPVILSELSISAdMDPTPGSELMVALNLLPEGSRTALGNSIAYQkq 1204
                  ********7777666667778**************97766..478999****************9999***********888888988888888755 PP

                  SS-..BEEEEEESEEEEE--X CS
       PS-DH  275 edG..rvvaeieglrlrrver 293 
                  +dG  r+v+  +g+rl+ v++
  EEA20741.1 1205 KDGkfRPVLIASGIRLQVVGE 1225
                  566444777777777777765 PP

>> Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   2.3e-05     0.021       1      38 [.     264     301 ..     264     301 .. 0.97
   2 !   58.6   0.0   6.1e-19   5.5e-16      55     117 ..     299     362 ..     298     363 .. 0.95
   3 ?   -3.2   0.0       9.3   8.4e+03      29      80 ..     678     730 ..     667     733 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 2.3e-05
                      SEEEEEEEEEE--STSSSTSTTHHHHHHHHHHHHHHHT CS
  Ketoacyl-synt_C   1 yavikgsavnsdgahnsltapngeaqaraiekalaeag 38 
                      +avi++s+vn+dg+++++  pn++aq+++ ++++a+ag
       EEA20741.1 264 HAVIVNSGVNHDGKTAGIFLPNADAQEKLARSVYAKAG 301
                      69*********************************997 PP

  == domain 2  score: 58.6 bits;  conditional E-value: 6.1e-19
                      HHHHHHHHHHHHHHHGGGGG.SCTSEEE-THHHH-B-GGGHHHHHHHHHHHHHHHTEE--BTT- CS
  Ketoacyl-synt_C  55 plgDpiElealkkvfgekar.kqplavgSvKsniGHleaAaGvaelikvvlalkhgvipptlnl 117
                      ++gD +E+++++kvfg++a   + l+vgS+KsniGHle+ +Gva+++k++++lk+++ipp+ln+
       EEA20741.1 299 KAGDDAEIKSISKVFGRQAGrLADLPVGSIKSNIGHLESSSGVAGILKAIMVLKNNQIPPNLNY 362
                      68***************9988667**************************************97 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 9.3
                      HHHHHHHHHT--GGGEEEEE-SS-SSHHHHHHHHHHHHHHHGGGGG.SCTSEE CS
  Ketoacyl-synt_C  29 aiekalaeagvdpedvdyveahgtgtplgDpiElealkkvfgekar.kqplav 80 
                      ai+  ++++ +   +v  v+   + t  gD + +e l++v+++ +  +++l v
       EEA20741.1 678 AITPRIRNITTGRLTVACVNSPESTTISGDVAAIEELQAVLDSVTVfNRRLVV 730
                      5556667777777899999999999******9999999999887655555555 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.0      0.48   4.3e+02      16      62 ..    1485    1532 ..    1467    1561 .. 0.70
   2 !   60.8   0.0     3e-19   2.7e-16       5     133 .]    2005    2141 ..    2002    2141 .. 0.84

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.48
                    HHH-TT-EEEEEES-H......HHHH.HHHHHHEEEEEEEEE----.S-EEE- CS
  ADH_zinc_N_2   16 aatggegvDvvldtvg......gealleaslkvlpggGrlvsiggpplsaall 62  
                    +  + +++D+++ ++        + ++++++k+l+++Grlv i  +      l
    EEA20741.1 1485 QGFSANSFDLIFASIVlhatplMDVTMSNVRKLLKPEGRLVLIELT-----GL 1532
                    455567899999998888888956666*******888***988742.....33 PP

  == domain 2  score: 60.8 bits;  conditional E-value: 3e-19
                    EEEETTSTTHH....HHH-TT-EEEEEES-HHHHH.HHHHHHEEEEEEEEE--.--....S-EEE-CHHHCTTT-EEEE--GGG...-..-HHHH CS
  ADH_zinc_N_2    5 evidyrtedfe....aatggegvDvvldtvggealleaslkvlpggGrlvsig.gpp...lsaallkpakkrkgrsvkyeflfsmkas.aqadil 90  
                    +++ ++t +f+    ++t+g+gvDvvl+++ ge +l +s++++++ G++++ig  ++    + ++++ +k++  ++v+++ +  +++  + +  l
    EEA20741.1 2005 HIFSSHTRNFKkgimRSTRGKGVDVVLNSLSGE-FLMDSWDCVAPFGTFLEIGkTDIyghSQLNMAPFEKQATFAAVDTSHMYRLRPEyVSKG-L 2097
                    5557778999999999***************99.55*******999*******5555987555566666666677777777776777777777.* PP

                    HHHHHHHHHHH----EEEE.EEGGGHHHHHHHHHSS--SSEEEE CS
  ADH_zinc_N_2   91 eelaalieeGklrpvvdrv.fpleeaaeAhrylesgrarGKiVl 133 
                    +e+++++++G  +pv + + +p++++ +A+r++++++++GK+Vl
    EEA20741.1 2098 AEIFDMVDKGLYKPVHTVTeYPMSRIEDAFRLIAARKHVGKLVL 2141
                    **************999778***********************8 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.6   0.0   4.3e-19   3.8e-16       1      99 []    1419    1524 ..    1419    1524 .. 0.88

  Alignments for each domain:
  == domain 1  score: 59.6 bits;  conditional E-value: 4.3e-19
  Methyltransf_12    1 LeiGcGtGsllrallekl......pdieytgvDispsaiedakeklakrennnnnnvelealdlldldgg.....ssfDlvvasnvlhhlkd 81  
                       Lei +GtGs +++l e++         eyt++Dis+ ++e+a++k++++      ++++++ld++ ++ +     +sfDl++as vlh+++ 
       EEA20741.1 1419 LEIDAGTGSASMPLMESInrngrlLLDEYTYTDISSGFFERARNKFSQWAH----QINFKTLDISRDPLEqgfsaNSFDLIFASIVLHATPL 1506
                       8999*****************999999**********************97....55555555444443355567***************** PP

  Methyltransf_12   82 irevldnirklLkpgGrl 99  
                       ++ +++n+rklLkp+Grl
       EEA20741.1 1507 MDVTMSNVRKLLKPEGRL 1524
                       ****************97 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       8.4   7.5e+03      71      88 ..    1510    1527 ..    1504    1536 .. 0.85
   2 !   58.4   0.0     8e-19   7.2e-16       1     116 [.    1966    2087 ..    1966    2100 .. 0.89

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 8.4
                  HHHHHHHCEEEEEEEEEC CS
  ADH_zinc_N   71 tleaalkllkpgGrlvvv 88  
                  t+++  kllkp Grlv++
  EEA20741.1 1510 TMSNVRKLLKPEGRLVLI 1527
                  7888889********987 PP

  == domain 2  score: 58.4 bits;  conditional E-value: 8e-19
                  HHHHHHHHHHHHTT-EEEEEESSHHHHHHHHH.TT.ESEEEETTTC.HHHHHHHHHTTTSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSC..TS CS
  ADH_zinc_N    1 gvGlaavqlAkalGaeviavdsseeklelakk.lG.adevinykea.dlverikeltggegvdvvfecvGsgatleaalkllkpgGrlvvvGg..gk 92  
                  gvG+aa+q+Ak +Gae++a+++   k++l ++ +G ad  i ++ + ++++ i + t+g+gvdvv++ +  g+ l ++ ++++p G++  +G    +
  EEA20741.1 1966 GVGQAAIQIAKLIGAEIYATVGGTTKRKLIQDqYGiADSHIFSSHTrNFKKGIMRSTRGKGVDVVLNSLS-GEFLMDSWDCVAPFGTFLEIGKtdIY 2061
                  9******************************99********999999***********************.************************99 PP

                  SEEEEEHHHHHHTT-EE...EEE-SSC CS
  ADH_zinc_N   93 geeefdlrnlllkeksi...lGsllgs 116 
                  g+++++++++  k+ ++     s++++
  EEA20741.1 2062 GHSQLNMAPF-EKQATFaavDTSHMYR 2087
                  9999999994.6666652224555555 PP

>> KAsynt_C_assoc  Ketoacyl-synthetase C-terminal extension
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.9   0.0   4.9e-17   4.4e-14       1     110 [.     365     505 ..     365     507 .. 0.86

  Alignments for each domain:
  == domain 1  score: 52.9 bits;  conditional E-value: 4.9e-17
  KAsynt_C_assoc   1 PnpeipaleegrlkVvteptpw.pggi.....vgvNsfGfGGsnvHviLksnkkekrkeesk......................eeslprLlvls 67 
                     P+p ++ lee  + V+ e t++ p+g+     v+vNsfG+GG+n+H+iL++++++  +++++                      + +++rL+vls
      EEA20741.1 365 PKPGLN-LEERGIIVPLELTSLtPRGYvgprrVSVNSFGYGGTNAHAILEAYDRPCITDSHQsngnghghhsngitngitngitNGDSKRLFVLS 458
                     888899.9999999999999995666699999*********************8888877777888999**************999********* PP

  KAsynt_C_assoc  68 grteeaveallekleeh....lldaellsllneilseeisrlpyRGy 110
                     +++e ++ +++++l+++    +  ++  s l+++l+ ++s+lp+R  
      EEA20741.1 459 ANSEVSLGNVISNLRQWlmsnQSRDTSFSDLSYTLNVRRSKLPWRCS 505
                     *****************653323334445688888888888***965 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0       1.5   1.4e+03      35      75 ..     823     863 ..     800     874 .. 0.86
   2 !   43.3   0.1   2.9e-14   2.6e-11       4     170 ..    2168    2334 ..    2166    2349 .. 0.85

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 1.5
                 HHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHH CS
   adh_short  35 ekleevakelkeegakalaiqvDvtdreevealvekavkkl 75 
                  +l+++++++ + + k+++i++ +++r++v+++++ a k +
  EEA20741.1 823 GPLRQTLSHISNSSFKYTYIPTLIRNRNAVDTILALAGKTF 863
                 578999*************************9999887766 PP

  == domain 2  score: 43.3 bits;  conditional E-value: 2.9e-14
                  EEESTTSHHHHHHHHHHHHTT-EEEE.EESCHHHHHH...HHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGC CS
   adh_short    4 lvtGassGIGraiakelakeGakvvv.vdrseeklee...vakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfsel 96  
                  ++ G+ + +Gr +++ la++Ga ++v ++r++ ++++   + +++k+ g++++++++D+td+e+++a+  ++ ++l ++  ++++A +  ++p + +
  EEA20741.1 2168 VIGGGLGDLGRRMSHFLAEKGAGHIVtLSRRNIDIQQrssLEESIKKIGSTLHIVKCDITDEESMRAAATEI-SQLPPVRGIIQGALVLYDHPLEYM 2263
                  45566667**************9999899988777652224566777799*********************9.99********************** PP

                  SHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGG CS
   adh_short   97 seeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelapt 170 
                  + e+w   ++  ++g++++ +++      +     +  sSva+ v+  +++ YsA   + ++++++ +   + t
  EEA20741.1 2264 NVEDWMTALKPKVQGTLNMHKLLCSP---KTTDFFIMLSSVASIVGATSQSNYSAGNSFQDAFAHAQQATSSLT 2334
                  **********************9988...678889********************9999999988766554444 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.8   0.0   2.7e-12   2.4e-09       1      97 []    1418    1522 ..    1418    1522 .. 0.87

  Alignments for each domain:
  == domain 1  score: 37.8 bits;  conditional E-value: 2.7e-12
                       EEEET-TTSHHHHHHHCTS...T...SSEEEEEESSHHHHHHHHHHHHHTTTTEEEEESBCCGBS....SSTTTEEEEEEESTGGGSSHHHH CS
  Methyltransf_25    1 vLdlGcGtGrltlalakrl...g...kakvtgvDiseemleaareraeeeglnvefvqgdaedlp....fedgsfDlvvssgalhhlsdedl 82  
                       +L++ +GtG  ++ l + +   g     ++t +Dis+++ e+ar+++++   +++f + d+++ p    f ++sfDl+++s +lh ++   +
       EEA20741.1 1418 ILEIDAGTGSASMPLMESInrnGrllLDEYTYTDISSGFFERARNKFSQWAHQINFKTLDISRDPleqgFSANSFDLIFASIVLHATP--LM 1507
                       89999***********99865435667899******************9999*********7755446689*********98899877..55 PP

                       HHHHHHHHHHEEEEE CS
  Methyltransf_25   83 ekalkeiarvLkpgG 97  
                       + ++++++++Lkp+G
       EEA20741.1 1508 DVTMSNVRKLLKPEG 1522
                       678**********99 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2   0.0   7.9e-12   7.1e-09       2      96 .]    1420    1526 ..    1419    1526 .. 0.87
   2 ?   -0.1   0.0       1.6   1.5e+03      49      74 ..    2402    2427 ..    2347    2446 .. 0.80

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 7.9e-12
                       EET-TTSHHHHHHH....HTT....SEEEEEES-HHHHHHHHHHCCHHT-EEEETTEECCC..T..SS-TT-EEEEEEES-CCC-CCHHHHH CS
  Methyltransf_11    2 dvGcGtGrlaeala....krg....arvvgvDlskemlklakekaseeglkvefvvadaek..l..pfednsfDlvvssevlhhvedpekal 81  
                       ++ +GtG+ + +l+    ++g     +++ +D+s  + ++a++k s+  ++++f   d+++  l   f  nsfDl+++s vlh  + ++ ++
       EEA20741.1 1420 EIDAGTGSASMPLMesinRNGrlllDEYTYTDISSGFFERARNKFSQWAHQINFKTLDISRdpLeqGFSANSFDLIFASIVLHATPLMDVTM 1511
                       56678888888888777755677899**********************9999999999996453225999********************** PP

                       HHHHHHEEEEEEEEE CS
  Methyltransf_11   82 keiaRvLkpgGllvi 96  
                       ++++++Lkp+G+lv+
       EEA20741.1 1512 SNVRKLLKPEGRLVL 1526
                       ************985 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 1.6
                       TEECCCTSS-TT-EEEEEEES-CCC- CS
  Methyltransf_11   49 vadaeklpfednsfDlvvssevlhhv 74  
                       +  + ++ + d+ fD v+s+  l+ +
       EEA20741.1 2402 EDAIGETALSDHLFDHVTSRRKLEVI 2427
                       445567899***********999887 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.8   0.0   1.5e-11   1.3e-08       2     113 ..    1413    1530 ..    1412    1552 .. 0.85

  Alignments for each domain:
  == domain 1  score: 34.8 bits;  conditional E-value: 1.5e-11
  Methyltransf_31    2 dkglrvlDlGCGtGeltfelaeelgpkae.....vvGiDiseeaielArenaqklgldnveFeqgdiee..lekl.ledekfDlilsnevln 85  
                       + ++++l++ +GtG  +  l e ++ +++     ++  Dis    e+Ar++ ++     ++F+  di    le + ++ ++fDli++  vl+
       EEA20741.1 1413 KPNMKILEIDAGTGSASMPLMESINRNGRllldeYTYTDISSGFFERARNKFSQWAH-QINFKTLDISRdpLE-QgFSANSFDLIFASIVLH 1502
                       6799******************99999996666677777777777777776665555.6*********98455.66888************* PP

  Methyltransf_31   86 aladpdkileeiervlkpggilliedpr 113 
                       a++ +d ++ ++ ++lkp+g+l++ +  
       EEA20741.1 1503 ATPLMDVTMSNVRKLLKPEGRLVLIELT 1530
                       ***********************98876 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.3   0.0   1.9e-09   1.7e-06       7      67 .]    2465    2522 ..    2459    2522 .. 0.86

  Alignments for each domain:
  == domain 1  score: 28.3 bits;  conditional E-value: 1.9e-09
  PP-binding    7 vaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaayl 67  
                  va  +g   +e+ +d+++ +lGlDSl+++e+ +++++ f+v++  s+l++ +++ +la+++
  EEA20741.1 2465 VAAFMG---DEVPVDQPITNLGLDSLVSIEIKNWVKHIFKVPLQTSELMNARSIIALAKLI 2522
                  555555...34668*******************************************9876 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.0   2.6e-09   2.4e-06       7     160 ..    2177    2342 ..    2173    2346 .. 0.82

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 2.6e-09
                    HHHHHHHHHHTT-E..EEEEESSGGH..HHHHHHHHHHTTSE..EEE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHH CS
  adh_short_C2    7 GraiAkalaeeGae..vvltdlneea..kkrveelaeelgae..vlecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreef 95  
                    Gr + + lae+Ga   v l+ +n +   ++++ee  +++g++  +++cD+tdee+++a++ e+  ++  + +++  a +  +   p++ ++ e++
    EEA20741.1 2177 GRRMSHFLAEKGAGhiVTLSRRNIDIqqRSSLEESIKKIGSTlhIVKCDITDEESMRAAATEIS-QLPPVRGIIQGALVLYD--HPLEYMNVEDW 2268
                    777777888888873344444444434478999*******99555****************986.689******99999998..*********** PP

                    HHHHHHHTHHHHHHHHHHHH.......HCTSC.CEEEEEEEGGGTSBSTTTT.HHHHHHHHHHHHHHHHHHHHG CS
  adh_short_C2   96 draldvnlyslfllakaalp.......lmkeg.gsivnlssvgaervvpnyn.aygaaKaalealtrylAvelg 160 
                     +al+ ++++++++ k +         +m ++ +siv  +s +   + ++ + a + a  a  +lt+y   ++g
    EEA20741.1 2269 MTALKPKVQGTLNMHKLLCSpkttdffIMLSSvASIVGATSQSNYSAGNSFQdAFAHAQQATSSLTKYTTINVG 2342
                    ***************998766777788555556********999988777777***************988776 PP

>> Ubie_methyltran  ubiE/COQ5 methyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.0   7.4e-09   6.6e-06      39     155 ..    1406    1530 ..    1393    1538 .. 0.86
   2 ?   -1.8   0.0       1.8   1.6e+03      99     152 ..    1831    1883 ..    1826    1890 .. 0.84

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 7.4e-09
                       HHHH--S--TTEEEEES-TT-HHHHHHHHHHHHHH.....EEEEEES-HHHHHHHHHHHHHHTSS.TEEEEE--TTT-T..TS-T-EEEEEE CS
  Ubie_methyltran   39 veklvavkrgakvlDvagGtgDlafklsdsvgekg.....kvvvlDinenmLkvgekklkeegki.nieflqanaeeLp..feddsfDvvtv 122 
                       ++ +v +k+  k+l++ +Gtg  ++ l++s++++g     + +  Di++  ++ +++k  + + + n + l  +   L+  f+ +sfD++  
       EEA20741.1 1406 MKAVVHKKPNMKILEIDAGTGSASMPLMESINRNGrllldEYTYTDISSGFFERARNKFSQWAHQiNFKTLDISRDPLEqgFSANSFDLIFA 1497
                       44455566667************************999888899***************9988766777777777666544899******** PP

                       ES-GGG-S-HHHHHHHHHHHEEEEEEEEEEEE- CS
  Ubie_methyltran  123 sfGlrnvtDklkaLkeayrvlkpGGrlvvlefs 155 
                       s  l  ++ ++ ++ ++++ lkp Grlv +e++
       EEA20741.1 1498 SIVLHATPLMDVTMSNVRKLLKPEGRLVLIELT 1530
                       ******************************975 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 1.8
                       TEEEEE--TTT-TTS-T-EEEEEEES-GGG-S-HHHHHHHHHHHEEEEEEEEEE CS
  Ubie_methyltran   99 nieflqanaeeLpfeddsfDvvtvsfGlrnvtDklkaLkeayrvlkpGGrlvvl 152 
                        ++f+  na++ p   d  ++ + ++G+ n+ D   aL ++   +   G++  +
       EEA20741.1 1831 TLRFVDNNAMAEPLGPDQIELQACAYGV-NFKDVFIALGQMQPGVPMTGEVAGI 1883
                       5799***********************8.999*999999988777666666655 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.4   0.0   1.2e-08   1.1e-05      16     121 ..    1408    1530 ..    1396    1577 .. 0.70

  Alignments for each domain:
  == domain 1  score: 25.4 bits;  conditional E-value: 1.2e-08
  Methyltransf_23   16 llpklraggrvLdiGcGtGi....llevlrengf....svtgvDlspeaveiaekakkaqkdqfdeq............eaaepqgkfdlIv 87  
                       ++  +++++++L+i +GtG+    l+e++ +ng     ++t  D+s+   e+a+   + +++ ++++            e  +++++fdlI 
       EEA20741.1 1408 AVVHKKPNMKILEIDAGTGSasmpLMESINRNGRllldEYTYTDISSGFFERAR---NKFSQWAHQInfktldisrdplEQGFSANSFDLIF 1496
                       3334789999**999999962222344446676456789*******98888765...44444444443333444444444445888****** PP

  Methyltransf_23   88 lrevlehvpdppellrqiatllkpgGylllsepl 121 
                       ++ vl+  p +  +++++++llkp+G+l+l e +
       EEA20741.1 1497 ASIVLHATPLMDVTMSNVRKLLKPEGRLVLIELT 1530
                       *****************************98864 PP

>> DUF4113  Domain of unknown function (DUF4113)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   4.1e-05     0.037       1      44 [.    2760    2805 ..    2760    2807 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 4.1e-05
     DUF4113    1 erLmkalDaiNrrfGrgtvklaaqgl..kasWkmkrehlSprYTTr 44  
                  e+L ++++ai ++ G ++++ +   +  + sW+m re+lS++  T+
  EEA20741.1 2760 EKLEATFEAIITQVGDDALWTGILTTdeRNSWAMVREKLSSSSLTN 2805
                  5899*******************99622666**********99987 PP

>> Rtf2  Rtf2 RING-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00032      0.28      23      48 ..    2552    2577 ..    2529    2600 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00032
        Rtf2   23 kvdkeeekearwklCaLsqepLkkPi 48  
                    d++e+ ++ w +C+Ls+epL++P 
  EEA20741.1 2552 TNDHNEKTHHSWDCCKLSKEPLAQPL 2577
                  4499********************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (3154 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       541  (0.0301746); expected 358.6 (0.02)
Passed bias filter:                      499  (0.027832); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              20  [number of targets reported over threshold]
# CPU time: 1.42u 0.34s 00:00:01.76 Elapsed: 00:00:00.51
# Mc/sec: 18623.91
//
Query:       EEA20742.1  [L=606]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      7e-10   38.9   5.7      7e-10   38.9   5.7    1.7  2  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
    4.2e-06   26.0   0.7    8.6e-06   25.0   0.7    1.6  1  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.9   5.7   7.8e-14     7e-10       2      36 ..      14      47 ..      13      51 .. 0.85
   2 ?   -3.2   0.4       1.1   9.6e+03      21      27 ..     561     567 ..     554     569 .. 0.70

  Alignments for each domain:
  == domain 1  score: 38.9 bits;  conditional E-value: 7.8e-14
                S-HHHHHCT---ST.SSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus  2 aCdnCrkkKvKCda.kkPaCsnCkklnleCtfyses 36
                aC +Cr+++ +Cda + P Cs+C+++n++C  y  s
  EEA20742.1 14 ACVPCRQRHLRCDAvMPP-CSRCEQSNVKCY-YVAS 47
                9*************5555.***********9.5444 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 1.1
                 HHHHHCT CS
     Zn_clus  21 snCkkln 27 
                 +nCkk++
  EEA20742.1 561 RNCKKKS 567
                 5788776 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.0   0.7   9.6e-10   8.6e-06       1     208 [.     167     367 ..     167     439 .. 0.79

  Alignments for each domain:
  == domain 1  score: 25.0 bits;  conditional E-value: 9.6e-10
  Fungal_trans   1 ldrffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsL 97 
                   ++++ +nfh   p++  ++ l +        ++  ++ ll ++  +G++f +++++++    +           r++++     +sp      +q+ 
    EEA20742.1 167 MKLYYQNFHASHPFIIPQKALGNS-----DLARLLPSYLLSMMQYVGSHFHPDPSAKD----RY----------RKNAYM-GLNESPEATGFKVQAM 243
                   689999999777777777766666.....67889999******************998....22..........555555.223344443668**** PP

  Fungal_trans  98 lllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrpp...l.....lddsqinlpLP 186
                   ll++++  + ++ +++ + +  av +a +lg++  ++    ++++   ++ +es+rR++w  F++  ++ +  G  +   +      d++ ++++LP
    EEA20742.1 244 LLAAIVDHADGNEEQAGYRLKSAVIMASQLGMQSGSFG--GSNSYGNVIF-EESWRRTFWELFIVVHLFKTFSGQHNcddIqlsgyQDEDLLKMELP 337
                   *********************************76655..4456778888.99***********9999999999988544377777888888888** PP

  Fungal_trans 187 cddddlwesddaseetlvetk........l 208
                   cd+ ++  + +  +++ + +         +
    EEA20742.1 338 CDEATYFAAGTIPKSKTLLQLqnswrildN 367
                   **9998888777777766655555555443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (606 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       521  (0.0290591); expected 358.6 (0.02)
Passed bias filter:                      388  (0.0216409); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.27s 00:00:00.90 Elapsed: 00:00:00.47
# Mc/sec: 3887.68
//
Query:       EEA20743.1  [L=1242]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
   2.9e-234  779.3   0.0   3.6e-234  779.0   0.0    1.1  1  Gryzun       Gryzun, putative trafficking through Golgi
    2.9e-93  312.2   8.8    2.9e-84  282.7   7.6    2.2  2  Foie-gras_1  Foie gras liver health family 1
  ------ inclusion threshold ------
      0.092   13.3   0.1        2.4    8.7   0.0    2.8  2  TPR_19       Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> Gryzun  Gryzun, putative trafficking through Golgi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  779.0   0.0    6e-238  3.6e-234       1     592 []     649    1238 ..     649    1238 .. 0.95

  Alignments for each domain:
  == domain 1  score: 779.0 bits;  conditional E-value: 6e-238
      Gryzun    1 vvlkeedvvsflsasfvFekkegkvGeplqaQlaitSealkssapitlsevkveFegslkpiklkhdeeeeeesskskvsissvsleee...tesss 94  
                  +vlk+edvv++lsa++vF++ eg+vG++lq QlaitS+a+++++p++lsevk++Feg+l+pi+l++++ ++  +++  ++i++v+l++    tess+
  EEA20743.1  649 IVLKAEDVVTCLSAAMVFQRGEGNVGQALQLQLAITSHAHQQATPLRLSEVKIVFEGGLRPITLHAKDITD--DTNPLSHIYNVKLHDLassTESST 743 
                  79****************************************************************99775..778899999999999877788888 PP

      Gryzun   95 keseteklselkgsadLtlkpgqtkvfelaiilreaGeakvasvtlsveeekFdLeytisekeekeavwWaeskkgakkrrvrkdsdt.aikilPkP 190 
                    s+t+++++++g+adL++kpg+t+vf+++ i+re+Ge+++as+tl++eeekF++ y+++++e+++++wW ++ +g+ k+r++k +dt  +kilPkP
  EEA20743.1  744 FLSPTAHMASMIGQADLIFKPGETRVFNMTAIPREPGESRIASITLAIEEEKFNFLYVMTNHERDMSFWWRHGPRGSYKKRIGKGRDTaICKILPKP 840 
                  899*************************************************************************************9******** PP

      Gryzun  191 PkleiklpelkeqYYtnEkieLeleieNeEdeeaevklevrllGesesalkisvldeeeeaeeae.e..eeekeeslp..klgklessastelsivl 282 
                  P+++i+lp+lk +YYtnE+++L++ i+N+Ed++aev +++r+lG+++s lk+s++d++eea+e      e++ +   +  ++g l+ +a +e++++l
  EEA20743.1  841 PNIQIQLPNLKPHYYTNERVSLAVAIQNNEDDAAEVAMQIRILGQPHSLLKVSWSDDAEEATEFGgVsvETTIHL--KsrSVGILSPAAISEIPVIL 935 
                  ******************************************************999999988863233333333..2559**************** PP

      Gryzun  283 tetedpleyeleikasYhlvsdletpiiktlsvklslvnpFEAnYdllprlhpdpWPslFdveesealededakeakarglaqrwclvaklasFAee 379 
                  ++t d+leye++i+++Y lvsd+etpi+k++s++l++++pFEAnYdl+pr+hpd+WP+lF+++  ++ e    k+ k++gl+qrwc++ k++sFA+e
  EEA20743.1  936 SNTVDALEYEVDISVHYFLVSDPETPISKSISATLAFMRPFEANYDLVPRIHPDAWPNLFQLDTDSDGE----KADKPDGLQQRWCVSPKIVSFASE 1028
                  ***************************************************************887633....33457******************* PP

      Gryzun  380 dLvvedvdlevlsveggavcsvskspekpeveedgltikpeeleeaqFdlevqklsLddrrpvaldlaleikWrRkssessseaevntttlavprll 476 
                  +Lv+e+v++ +l+v+gga+c++    +++ ++ + ++i peel+ ++F l+vqk+sL+drr+valdl+l+ikWrR ss++++e+++++t+la+pr++
  EEA20743.1 1029 PLVIENVSVGLLEVNGGAICEIG---SERLTTPEATQILPEELRASEFILDVQKTSLEDRRSVALDLSLNIKWRRPSSPDQDEHTSTVTSLAMPRFT 1122
                  ***********************...34444567899************************************************************ PP

      Gryzun  477 vlgsEPRvLasvsassalpglihldytlENpsmHfLtFgltmeaseeFAFsGpKqttvqllPlSRrtvrYrllplvrgawirpqlvvvDkYFqkvLr 573 
                  ++++EPRvLas+s s+++pglih+dytlENpsmH LtF+ltm+ase+FAFsG+K++++ql+PlSR++vrY+++++++g+wi+p+lvvvD+YF+k+Lr
  EEA20743.1 1123 IPTGEPRVLASASPSKEHPGLIHMDYTLENPSMHTLTFSLTMDASEHFAFSGSKTRALQLVPLSRHKVRYNIFAFKSGMWIQPHLVVVDTYFNKTLR 1219
                  ************************************************************************************************* PP

      Gryzun  574 vlptegmkiDkkGllvwvd 592 
                  vlptegm++DkkG+lvwvd
  EEA20743.1 1220 VLPTEGMRADKKGILVWVD 1238
                  ******************7 PP

>> Foie-gras_1  Foie gras liver health family 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.5   0.0   1.8e-10   1.1e-06      27      78 ..     257     317 ..     245     336 .. 0.86
   2 !  282.7   7.6   4.8e-88   2.9e-84       1     258 [.     343     620 ..     343     621 .. 0.96

  Alignments for each domain:
  == domain 1  score: 28.5 bits;  conditional E-value: 1.8e-10
  Foie-gras_1  27 seAvrkfrkHiervkdv......vgrrgkgtlafygweaWearq...asvfAeLieeasip 78 
                  ++++r+++kH++r++++      + ++++gt++++++++W++r+   + vfAe+++e+++ 
   EEA20743.1 257 VDYYRDLSKHARRKRNRgtipppTIPPTQGTSQTLSMQGWNVRYefkLGVFAEFRQEMEAA 317
                  49*********************8888******************999**********943 PP

  == domain 2  score: 282.7 bits;  conditional E-value: 4.8e-88
  Foie-gras_1   1 rfnearlladviaikiirlllsngqpseAvrkfrkHiervkdvvgrrgkgtlafygweaWearqasvfAeLieeasipgltslqtqq.stleeq.... 93 
                  rfnearll dv+ai+iir+ll+++qp++Avr + +H+++++d+v r+gkgt ++ygweaW+ar+++v+A+Li++a++p++++    +  +l+++    
   EEA20743.1 343 RFNEARLLGDVLAIRIIRCLLWTSQPTAAVRFWLSHKNNTEDIVSRKGKGT-KNYGWEAWVARWSAVMAQLISRAELPAFSAEFLLNpARLYDSifhp 439
                  8**************************************************.*****************************9885531344444**** PP

  Foie-gras_1  94 ............pwellhhagyyyqlaakhakerrelaeqiandpe.......qspassiassayvydtylapepheeyplsgseekgvahskliidl 172
                              +we lhh gy++ ++a+h+ +rr+laeqi   pe       q pas+ + +++ yd+ylapep  e+p +++   g++h++li+++
   EEA20743.1 440 pekgfssdenllAWEHLHHQGYWLDRSARHTVRRRQLAEQI---PEehrvtadQVPASQAVAQSQFYDNYLAPEPATEAPGPDD--SGFNHNALILQT 532
                  *****************************************...777788999*******************************..************ PP

  Foie-gras_1 173 LekaleeFskrkqtRlaeelsleiAeeylrlgdwkkalellqpl..tlsyrkegWwsLleevlwalrecalkvqdvkdvlavdleLls 258
                  L+++l+ F  r+q R++e+lsleiA+ ++++++w++a+++l+pl   l++rke Ww L++e++w+lr cal++ d ++ + v +eLls
   EEA20743.1 533 LKASLQHFAARDQVRKVESLSLEIAQFHIKAKQWQEAYDILKPLwpHLTWRKEHWWDLMSEFAWTLRSCALELHDIDTLVWVHWELLS 620
                  **************************************************************************************98 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.0      0.09   5.4e+02       3      44 ..     317     371 ..     315     374 .. 0.71
   2 ?    8.7   0.0   0.00041       2.4      25      54 ..     550     579 ..     527     593 .. 0.76

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.09
      TPR_19   3 aegdyaeA......lalleqalqedpknaearl.......lLAeallalgqldeA 44 
                 a+ ++++A      ++ +e++   +p   earl       + +++ll + q+++A
  EEA20743.1 317 AQRNFEAAyetlfgQEVFESIAGWNPRFNEARLlgdvlaiRIIRCLLWTSQPTAA 371
                 6777777777777788888888889998888884444333447788877777777 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.00041
      TPR_19  25 aearllLAeallalgqldeAealLdalpee 54 
                 + + l  A+ +++++q++eA ++L++l+++
  EEA20743.1 550 ESLSLEIAQFHIKAKQWQEAYDILKPLWPH 579
                 5677899******************99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1242 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       423  (0.0235931); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.81u 0.31s 00:00:01.12 Elapsed: 00:00:00.49
# Mc/sec: 7640.08
//
Query:       EEA20744.1  [L=505]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-40  138.3   0.0      2e-40  138.3   0.0    3.1  3  RXT2_N    RXT2-like, N-terminal


Domain annotation for each model (and alignments):
>> RXT2_N  RXT2-like, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.3   0.0   1.1e-44     2e-40       1     156 []      36     175 ..      36     175 .. 0.96
   2 ?   -2.2   5.1      0.21   3.7e+03      10      77 ..     197     266 ..     194     280 .. 0.48
   3 ?   -2.3   2.8      0.23     4e+03      54      81 ..     311     331 ..     280     363 .. 0.44

  Alignments for each domain:
  == domain 1  score: 138.3 bits;  conditional E-value: 1.1e-44
      RXT2_N   1 tNRGnKLkkkaefvhegrLnsskgdeelkkkveyngserkilsrnpierskrkkkekekeekeeeeedeegdeededdddee..eaeaaeenpykkvrl 97 
                 tNRGnKL+ +a++vheg+L+ s++ + +k+kve++g++r+il+rnp+++                  d+eg+e+d d++ ++  eaeaae+np++ + l
  EEA20744.1  36 TNRGNKLQVNAKYVHEGALGFSNPHDFYKQKVEHAGYTRYILHRNPPRY------------------DSEGEEIDGDEEPDTegEAEAAEDNPFAGIAL 116
                 8************************************************..................88888888777776677999************ PP

      RXT2_N  98 eelLaPltspsdlithpslsrtykskaLteLalqlieliekEqeslvklkkLlevllGd 156
                 e++L+Pl+++s+l++hp+ls++y+skaL ++++ + e +++E++ l ++++L++ +lGd
  EEA20744.1 117 EHILCPLKQASELPDHPTLSQPYRSKALPTMIKAIDEKLRRERALLARAHNLHRLFLGD 175
                 **********************************************************9 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.21
      RXT2_N  10 kaefvhegrLnsskgdeelkkkveyng.serk.ilsrnpierskrkkkekekeekeeeeedeegdeeded 77 
                 +ae  h+++ ++ ++ ++ +  +  ng ++r+  +s n+ ++++ ++ e +++  +e++++ e++e +++
  EEA20744.1 197 HAEAAHQQQTDNGSQGANGRVDIVNNGdRTRMnTVSSNKDKQNTGDDVEMTEAPMSETDKNAETKELKKE 266
                 5666666666666666666633334441333224444444443444433333334444444444444433 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 0.23
      RXT2_N  54 k.....kekekeekeeeeedeegdeededddde 81 
                 +     +             e+gd + +d +++
  EEA20744.1 311 SspqalD------------AEQGDTVMQDASES 331
                 0221111............11111111111111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (505 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1063  (0.0592894); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.67u 0.33s 00:00:01.00 Elapsed: 00:00:00.48
# Mc/sec: 3164.92
//
Query:       EEA20745.1  [L=199]
Description: phospholipid methyltransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-34  118.4   3.9    3.8e-33  114.0   3.0    2.3  2  PEMT      Phospholipid methyltransferase
  ------ inclusion threshold ------
      0.058   13.8   1.0       0.16   12.3   1.0    1.7  1  EPV_E5    Major transforming protein E5 family
      0.059   13.4   0.0      0.081   12.9   0.0    1.1  1  DUF1223   Protein of unknown function (DUF1223)


Domain annotation for each model (and alignments):
>> PEMT  Phospholipid methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0     0.024   1.4e+02      74     104 ..      18      48 ..      10      50 .. 0.87
   2 !  114.0   3.0   6.4e-37   3.8e-33       5     105 ..      89     188 ..      86     189 .. 0.97

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.024
        PEMT  74 aglllallvllvylialkfvEephlakiYgk 104
                  +l++a+ +++++++a++ + + +l +i+g 
  EEA20745.1  18 SALAIAFNPIFWNIVARQEYKNHFLTRIFGS 48 
                 458899999********************96 PP

  == domain 2  score: 114.0 bits;  conditional E-value: 6.4e-37
        PEMT   5 lGlllialglllvlssiealgefgtfygdfFlelmdklvtsGiYrylnnPeyvgstlgflGlaLitgsaaglllallvllvylialkfvEephlakiYg 103
                 +++ l+a+g++lvlss++alg++gt++gd+F++lmd++vt+++++++  P+y+gstl+flG++L++g++aglll+l v+++y++al+ +E+p++a+iY+
  EEA20745.1  89 IAYGLFATGNVLVLSSMWALGVTGTYLGDYFGILMDAPVTGFPFNVTGSPMYWGSTLSFLGTSLYYGKVAGLLLTLEVFVLYWFALR-WEDPFTAEIYA 186
                 5899***********************************************************************************.**********9 PP

        PEMT 104 kr 105
                 kr
  EEA20745.1 187 KR 188
                 97 PP

>> EPV_E5  Major transforming protein E5 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   1.0   2.7e-05      0.16       4      34 ..     149     180 ..     146     183 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 2.7e-05
      EPV_E5   4 GLLLfLGLtfGLqLmLLvfLLfffLvWW.Dqf 34 
                 G  L+ G   GL L L vf+L++f   W D f
  EEA20745.1 149 GTSLYYGKVAGLLLTLEVFVLYWFALRWeDPF 180
                 556899999************99966551555 PP

>> DUF1223  Protein of unknown function (DUF1223)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   1.4e-05     0.081      31      67 ..     162     198 ..     154     199 .] 0.89

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.4e-05
                 EEEEEE-STT-SSSS--TT--HHHHHHHHHHHHHTT- CS
     DUF1223  31 vaLalhVdYwdylGWkDtfassefterQrayaealgl 67 
                 + L + V Yw  l W+D+f  + +++r r+ a+a+++
  EEA20745.1 162 LTLEVFVLYWFALRWEDPFTAEIYAKRERERAKAAKS 198
                 67888899*********************99998775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (199 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       431  (0.0240393); expected 358.6 (0.02)
Passed bias filter:                      278  (0.0155056); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.30s 00:00:00.79 Elapsed: 00:00:00.48
# Mc/sec: 1241.93
//
Query:       EEA20746.1  [L=1223]
Description: intermediate filament protein (Mdm1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.4e-49  166.0   1.2    3.8e-48  163.9   1.1    2.2  2  PXA           PXA domain
    5.2e-24   85.0   0.0    2.7e-23   82.7   0.0    2.4  1  Nexin_C       Sorting nexin C terminal
    1.2e-19   70.4   1.2    2.7e-19   69.2   0.4    2.0  2  PX            PX domain
      5e-13   49.4   0.2    2.3e-12   47.2   0.2    2.3  1  RGS           Regulator of G protein signaling domain
      0.002   18.1   1.0       0.22   11.5   0.1    3.1  3  LRR19-TM      Leucine-rich repeat family 19 TM domain
  ------ inclusion threshold ------
      0.061   13.4   4.1        1.4    9.1   1.4    3.6  4  Mod_r         Modifier of rudimentary (Mod(r)) protein
        5.3    7.4  11.0       0.74   10.1   5.0    2.8  2  ABC_tran_CTD  ABC transporter C-terminal domain


Domain annotation for each model (and alignments):
>> PXA  PXA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  163.9   1.1   1.5e-51   3.8e-48       3     180 ..     103     283 ..     101     285 .. 0.96
   2 ?   -2.9   0.0       2.2   5.7e+03      91     128 ..    1048    1087 ..     990    1099 .. 0.55

  Alignments for each domain:
  == domain 1  score: 163.9 bits;  conditional E-value: 1.5e-51
         PXA   3 eldeelhellalilrdfVlsWYskissdeeFptevrsilrsviralanrlkkvDlaqllltrlldlltshlrdyrqaeekvkskkae......eesdld 95 
                  ++e+++ell+l+ rdf++sWY +is++ +F++e++++lr +++++++rl++ D+++l+++r++++lt+hl+d+++ae+++++++        ee+ l+
  EEA20746.1 103 VVSEAIDELLQLASRDFIRSWYGHISKNLAFINEIDRALRIALESIRDRLSSEDVTSLVVSRIVPILTTHLKDFDRAERAIRGRNLArsvtesEELGLA 201
                 799********************************************************************************9998************ PP

         PXA  96 laakffalephpalsavlrdieeskeaelaylrslverlLslllppedlesetvrtlvreilanvvlkplleklsdPdfinqlii 180
                 +a+k++++++hpa++  l   +++k+ +++y r+lv  lL++llp + l+s++v++l+rei+a++vl+p++++lsdPd++nq+++
  EEA20746.1 202 IASKYRDGRLHPAVAVSL---ADQKTIQQDYVRKLVMGLLPQLLPDNLLTSRAVSVLIREIVACAVLLPVITLLSDPDTWNQILE 283
                 ************998434...568899*******************************************************986 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 2.2
         PXA   91 esdldlaakffalephpalsavlrd..ieeskeaelaylr 128 
                   + ++  ++f++ e++p ++++++   ++ + ++ +++lr
  EEA20746.1 1048 AEAEAELNAFEDRELEPFIKPICDLflEAFELNRGNNWLR 1087
                  2233444578888888888888866653333344455555 PP

>> Nexin_C  Sorting nexin C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.7   0.0   1.1e-26   2.7e-23       1     111 [.    1085    1190 ..    1085    1191 .. 0.95

  Alignments for each domain:
  == domain 1  score: 82.7 bits;  conditional E-value: 1.1e-26
     Nexin_C    1 WlrrqaltvlkqvlqqllgdtierwlkekiekltseeavaslikklrdalWPdgeskaesaperseeeklrtraearklLlellpdalvsvvGrkna 97  
                  Wlr++a+   ++vl+qllg+tier+++++ ++l ++++++++ +  + ++WP+g     ++ +r++++k+++++ea  ++ +l+pd++++vvGr+na
  EEA20746.1 1085 WLRGRAV---VVVLHQLLGGTIERKVRDSAKSLVEDDNLLRYMTLAKATMWPGG--VMRKPVVRTSSQKSKSKNEASFMMAALIPDLAGNVVGRANA 1176
                  *****99...******************************************88..4444568********************************** PP

     Nexin_C   98 eealkrifellQnp 111 
                  ++a+++i+++l+np
  EEA20746.1 1177 QSASRKIYDILNNP 1190
                  ************98 PP

>> PX  PX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       1.3   3.4e+03      72      88 ..     612     678 ..     526     681 .. 0.46
   2 !   69.2   0.4     1e-22   2.7e-19      16     112 ..     877     974 ..     864     975 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.3
                 S..................................................CTTSHHHHHHHHHHHH CS
          PX  72 v..................................................rkkdeefiekrrkgLe 88 
                                                                    ++k++e+ie+  ++L+
  EEA20746.1 612 DvqsngklfddvessprrsvdsdrsarlfdddydtdplsysfsmssqngdaEAKNTEVIENMEQALN 678
                 0333333333333333333333334444444444444444444445555555566666666666665 PP

  == domain 2  score: 69.2 bits;  conditional E-value: 1e-22
                 TSSEEEEEEEEEETTS....SSEEEEEEEHHHHHHHHHHHHHHHTTSTSTSSSTSGSSSSSCTTSHHHHHHHHHHHHHHHHHHHTSCHHHHSHHHHHHH CS
          PX  16 skkhsyylyevelktg....akewtvkRrYsdFeeLhskLlrkfprvkiPplPkkvlfgsvrkkdeefiekrrkgLeeyLqrllnhpelrnsevlteFL 110
                 + +  +y++ev+++ g    a +w v RrYs+F+eLh+kL+ ++p+v+  ++P+++++ +    +++f++krr +Le yLq+ll  pe ++s++l+ FL
  EEA20746.1 877 GNEFAIYVIEVRRNAGeqmpAASWAVPRRYSEFHELHQKLRMRYPSVRQLEFPRRRMMMK---LQKDFLQKRRVALETYLQQLLLLPEVCRSRDLRAFL 972
                 5667789999999999****************************************9986...************************************ PP

                 HS CS
          PX 111 ev 112
                 ++
  EEA20746.1 973 SQ 974
                 86 PP

>> RGS  Regulator of G protein signaling domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.2   0.2     9e-16   2.3e-12       2     117 ..     418     552 ..     417     553 .. 0.90

  Alignments for each domain:
  == domain 1  score: 47.2 bits;  conditional E-value: 9e-16
                 HHHHHTSHHHHHHHHHHHHHTTCTHHHHHHHHHHHHHTS..............SHHHHHHHHHHHHHHHHTSTTSTTSSTS-HHHHHHHHHHHCSS... CS
         RGS   2 leslledqpgrslFreFlesefseenlsFwlaveefkka..............keqeelkkkakeIyneylapsspkelnidkklreelekrleke... 83 
                 l +l+ + +g+s+F eF++++++   ++Fw+ v++f++               +  ++ ++++  I ++yl   s+ eln+ ++ r+ ++++l+     
  EEA20746.1 418 LVDLMRNASGLSYFMEFMDRQNKMSLVQFWIVVDGFRNPleddfgdesstssaAWTSADVSDMVLINENYL---SKPELNVLEESRDAVKAFLKAGkra 513
                 668999999*************************************999755422233333477899****...********************999** PP

                 .....STTTTTTHHHHHHHHHHHHHHHHHHHHTSHHHHH CS
         RGS  84 .....qpsrklfeeaqeevfellekdsypkFlkselylr 117
                      ++ r++  + q+ ++e +e+++ypkF +s+l+ +
  EEA20746.1 514 speqyRKARTAILMTQSTILEEMESKYYPKFRDSDLFYK 552
                 *************************************87 PP

>> LRR19-TM  Leucine-rich repeat family 19 TM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.5   0.1   8.6e-05      0.22      15      42 ..      34      61 ..      30     104 .. 0.90
   2 ?   -2.1   0.0       1.5   3.8e+03      23      58 ..     260     295 ..     247     312 .. 0.66
   3 ?    3.4   0.1      0.03        77      82      99 ..     750     771 ..     700     774 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 8.6e-05
    LRR19-TM 15 Waylvgvvvlalvtsllillaikcklly 42
                Wa+++gv v+ ++++  ill++k k+ y
  EEA20746.1 34 WAFVAGVLVTCVCICSAILLTVKTKSEY 61
                **********************998755 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.5
    LRR19-TM  23 vlalvtsllillaikckllykfllsYrHrrLeesea 58 
                 v   v+  +i+l     ++ ++l  Y    L+++++
  EEA20746.1 260 VACAVLLPVITLLSDPDTWNQILETYGRTALNDRKT 295
                 333333345666667788888888888888888764 PP

  == domain 3  score: 3.4 bits;  conditional E-value: 0.03
    LRR19-TM  82 d....ddDGfiEDkYidteedl 99 
                 d    d+  fiED+Y d+e d 
  EEA20746.1 750 DelfpDEKKFIEDEYADPEGDE 771
                 146669999*******998765 PP

>> Mod_r  Modifier of rudimentary (Mod(r)) protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0       4.2   1.1e+04      99     120 ..     187     208 ..     185     213 .. 0.83
   2 ?    1.9   0.1     0.083   2.1e+02       3      52 ..     488     539 ..     486     548 .. 0.84
   3 ?    9.1   1.4   0.00053       1.4      28      97 ..     792     859 ..     783     861 .. 0.87
   4 ?   -2.3   0.0       1.6   4.2e+03      95     129 ..     973    1008 ..     930    1010 .. 0.59

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 4.2
       Mod_r  99 rLqtavaeaeeeSealaeefle 120
                 +L  +v+e+ee+  a+a++  +
  EEA20746.1 187 NLARSVTESEELGLAIASKYRD 208
                 7889999****99999998766 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.083
       Mod_r   3 lSkeeLqelledeeklealvk..tlpevkqlkeekeellaeneslaeknlsl 52 
                 lSk eL+ l e+ ++++a++k  +  + +q++++++ +l ++  ++e+  s+
  EEA20746.1 488 LSKPELNVLEESRDAVKAFLKagKRASPEQYRKARTAILMTQSTILEEMESK 539
                 899*****************965446689*********99999999987766 PP

  == domain 3  score: 9.1 bits;  conditional E-value: 0.00053
       Mod_r  28 vkqlkeekeellaeneslaeknlslepeleelrselqekleelkelekefeekeqeldellqkfspdall 97 
                 + +l+ee e+l +++es+++  l ++ el+++ +el    ++ +++++e ++ke + ++++ + s+++l+
  EEA20746.1 792 IVALTEEIEKL-NAQESVLD-TLTRKAELTNNTAELRILSKSKASIQREIRRKEMQRQQYVIQESDNSLY 859
                 66889999999.66666666.8*************************************99888888887 PP

  == domain 4  score: -2.3 bits;  conditional E-value: 1.6
       Mod_r   95 allarLqtavaeaeeeSealaeeflege.ieldeFv 129 
                  + +a+L + + +++ e+++++++++++    +d+F+
  EEA20746.1  973 SQQALLPHGAPASDGETKDIVSRIYNSVaDGMDDFL 1008
                  334557777778888888888888854436667776 PP

>> ABC_tran_CTD  ABC transporter C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   5.0   0.00029      0.74      12      62 ..     794     844 ..     788     845 .. 0.94
   2 ?   -2.6   0.3       2.7     7e+03      44      62 ..    1041    1059 ..    1024    1061 .. 0.57

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00029
  ABC_tran_CTD  12 eleaeIeaLEeeiaeleaeladpelysdpeklaelsaeleeleaeLeelye 62 
                   +l +eIe+L ++ + l++   ++el+++ ++l  ls+ ++ ++ e+ ++++
    EEA20746.1 794 ALTEEIEKLNAQESVLDTLTRKAELTNNTAELRILSKSKASIQREIRRKEM 844
                   6899*******************************************9997 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 2.7
  ABC_tran_CTD   44 aelsaeleeleaeLeelye 62  
                    +e     +e+eaeL++ ++
    EEA20746.1 1041 TEDAMTAAEAEAELNAFED 1059
                    4444445566666655554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1223 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       861  (0.0480228); expected 358.6 (0.02)
Passed bias filter:                      574  (0.0320152); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.83u 0.27s 00:00:01.10 Elapsed: 00:00:00.41
# Mc/sec: 8884.04
//
Query:       EEA20747.1  [L=294]
Description: Glutaredoxin domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.7e-13   50.6   0.0    3.9e-13   49.4   0.0    1.7  1  Glutaredoxin    Glutaredoxin
  ------ inclusion threshold ------
      0.027   15.5   0.8       0.22   12.5   0.0    2.6  2  Conotoxin       Conotoxin
      0.039   13.4   5.7       0.06   12.8   5.7    1.2  1  PBP_sp32        Proacrosin binding protein sp32
      0.082   11.7   4.2      0.099   11.5   4.2    1.0  1  DUF4551         Protein of unknown function (DUF4551)
       0.19   12.4   0.2       0.19   12.4   0.2    1.9  2  DUF680          Protein of unknown function (DUF680)
       0.35   10.6   2.2       0.49   10.2   0.1    2.1  2  TraF            F plasmid transfer operon protein


Domain annotation for each model (and alignments):
>> Glutaredoxin  Glutaredoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.4   0.0   1.3e-16   3.9e-13       1      57 [.     184     245 ..     184     248 .. 0.91

  Alignments for each domain:
  == domain 1  score: 49.4 bits;  conditional E-value: 1.3e-16
                   EEEEESTSSHHHHHHHHHHHHTTGG..EEEEEGCCSH...HHHHHHHHHHTSSSSSEEEETT CS
  Glutaredoxin   1 vvlftkptCpyCkkakrlLkelgvk..feeidvdkde...eireelkelsgvrtvPqvfidg 57 
                   +++f+k++Cp+++kak +L+++++     ++++dk++   ++++ l +++g+rtvP+v ++g
    EEA20747.1 184 IIVFSKSYCPFSRKAKSILNQYNIVpaLYIVELDKHAlgpQLQKLLGKITGRRTVPNVLVNG 245
                   79*********************66456899999997888*********************9 PP

>> Conotoxin  Conotoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   7.5e-05      0.22       5      49 ..      12      56 ..       7     101 .. 0.81
   2 ?    0.4   0.1      0.45   1.3e+03      36      43 ..     159     166 ..     132     197 .. 0.57

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 7.5e-05
                XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
   Conotoxin  5 cvlivavLllttlvtadldgdqpadrkakrledrkseekkklkke 49
                +v++v++L +t ++t   +g q  ++++k +  ++++   ++kk+
  EEA20747.1 12 VVVVVFLLVFTYFTTDTGGGIQSHRFYKKTVAAMDNAHTATIKKN 56
                566666666678888888888999999999999998888877765 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.45
                 XXXXXXXX CS
   Conotoxin  36 edrkseek 43 
                 ++ ++ee+
  EEA20747.1 159 HETSKEEE 166
                 11111111 PP

>> PBP_sp32  Proacrosin binding protein sp32
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   5.7     2e-05      0.06     113     237 ..      34     171 ..      20     177 .. 0.70

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 2e-05
    PBP_sp32 113 nrvyyakrvrcs...kvvsilssdtlkevevsaevsslsaetPivteatstekeafqp..wperllnnvee....llkssl.slggkekapeakpkeeq 201
                  + +y k v      ++ +i+  +  k+   ++ +  l +e    ++++ t + +  p  + e++++ +         s++ s+ g+ k p  kpke+q
  EEA20747.1  34 SHRFYKKTVAAMdnaHTATIKKNNEAKDAKDRSHIQRLDLENNNNNNNGGTRRTTSSPnsYNEKQEKPIGAshgkADDSDEiSVAGRTKMPIPKPKEDQ 132
                 577999999887666889***********************************987763345666655544666656665449*************999 PP

    PBP_sp32 202 l.lekkqeqleehkteekkkq.eeqeeee.keeeakqee 237
                 + l++k  +  + + e k ++  e + e  keee ++e 
  EEA20747.1 133 VrLSEKEPEAVDKPVESKSDVaTEHKHETsKEEEEEREA 171
                 535555544444555544443122222222333333333 PP

>> DUF4551  Protein of unknown function (DUF4551)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   4.2   3.3e-05     0.099     122     250 ..      46     183 ..      20     216 .. 0.49

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 3.3e-05
     DUF4551 122 spskasekksrressgaa.kkssslnessl.dakekeektvskksqlslsl.selrklseeekeelesekalkslrsasrplPesl..lsrapkpp... 212
                 +++  ++ + ++++++   k  s++++ +l +++++++ ++ ++++ + s   +++k   +++ ++++  +++ + ++  p P++   ++r ++++   
  EEA20747.1  46 DNA--HTATIKKNNEAKDaKDRSHIQRLDLeNNNNNNNGGTRRTTSSPNSYnEKQEKPIGASHGKADDSDEISVAGRTKMPIPKPKedQVRLSEKEpea 142
                 222..2222222222222366677777777444444444444444444444333344444555566666677777777777776663344444333345 PP

     DUF4551 213 .sspkeppssslsk.der.dskseessqvelrlgsvlsrll 250
                   +p e++s    + +++ ++++ee+++++ +l s+l+r++
  EEA20747.1 143 vDKPVESKSDVATEhKHEtSKEEEEEREASAELDSILKRSP 183
                 43333333333221022202222223355666666666654 PP

>> DUF680  Protein of unknown function (DUF680)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.2   6.5e-05      0.19      13      37 ..      41      63 ..      37      70 .. 0.80
   2 ?   -2.9   0.1         4   1.2e+04      28      29 ..     156     157 ..     143     172 .. 0.50

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 6.5e-05
      DUF680 13 PaAtakvDtsaTaSirkthkladsg 37
                ++A+   D+++Ta i+k+++++d++
  EEA20747.1 41 TVAA--MDNAHTATIKKNNEAKDAK 63
                7899..***********76666655 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 4
      DUF680  28 rk 29 
                 ++
  EEA20747.1 156 EH 157
                 22 PP

>> TraF  F plasmid transfer operon protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   1.0      0.17   5.1e+02      46      63 ..     132     149 ..      92     171 .. 0.48
   2 ?   10.2   0.1   0.00016      0.49     102     153 ..     153     204 ..     146     208 .. 0.85

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.17
        TraF  46 rkeleelldkAilnPtee 63 
                 + +l e++ +A+++P e 
  EEA20747.1 132 QVRLSEKEPEAVDKPVES 149
                 222222222222222211 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.00016
        TraF 102 rPvsnlarkvlndarkeekeaalkklakeygLlfFyrgkcpyceaqapilqa 153
                   +++ +   +++ +++e +a l ++ k+  +++F ++ cp+++++  il++
  EEA20747.1 153 VATEHKHETSKEEEEEREASAELDSILKRSPIIVFSKSYCPFSRKAKSILNQ 204
                 5566677777888888999999************************999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (294 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1544  (0.0861175); expected 358.6 (0.02)
Passed bias filter:                      684  (0.0381505); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.46
# Mc/sec: 1928.27
//
Query:       EEA20748.1  [L=192]
Description: 60S ribosomal protein L9, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.3e-23   82.1   3.8    6.7e-11   42.7   0.4    2.1  2  Ribosomal_L6  Ribosomal protein L6


Domain annotation for each model (and alignments):
>> Ribosomal_L6  Ribosomal protein L6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.7   0.4   3.7e-15   6.7e-11       1      76 []      12      85 ..      12      85 .. 0.89
   2 !   40.9   0.2   1.4e-14   2.5e-10       1      76 []      97     180 ..      97     180 .. 0.97

  Alignments for each domain:
  == domain 1  score: 42.7 bits;  conditional E-value: 3.7e-15
                  CSTTEEEEEETTTEEEEEESSEEEEEE-CTT.SEEEEEECSTEEEEEECSESCHHHHHHHHHHHHHHHHHHHHHHTC CS
  Ribosomal_L6  1 iPvgvrvsikggqlvlvlGpkgeltreipeg.vtvevkvegnkvtvivvsgidkekvAligtvrslinnmikGVteg 76
                  iP++v+++i + ++v+v Gp+g lt ++++  v +  + + n++  +  +g +k  +  ++tvr+linn i GVt g
    EEA20748.1 12 IPENVTINIRS-RIVTVEGPRGKLTKDLSHIsVSFGRP-DKNTISIELHHGARKGIA-TLRTVRTLINNLIIGVTRG 85
                  8*********6.******************85555544.666888888999999999.****************976 PP

  == domain 2  score: 40.9 bits;  conditional E-value: 1.4e-14
                   CSTTEEEEEET......TTEEEEEESSEEEEEE-CTTSEEEEEECSTEEEEEECSESCHHHH....HHHHHHHHHHHHHHHHHHTC CS
  Ribosomal_L6   1 iPvgvrvsikg......gqlvlvlGpkgeltreipegvtvevkvegnkvtvivvsgidkekv....AligtvrslinnmikGVteg 76 
                   +P++v+++ +g      ++++++lG+k  ++++   gv+v   +  n++++  +sg++ e v    A+i++++++ n++i+++ +g
    EEA20748.1  97 FPINVNIEKNGetgnyeVEIRNFLGEKIVRRITAQAGVEVI--TSPNVKDELQLSGNSLEAVsqsaADIQQICRVRNKDIRKFLDG 180
                   8*************************************999..559*************************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (192 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       515  (0.0287244); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1293.75
//
Query:       EEA20749.1  [L=577]
Description: Patatin-like serine hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-34  118.8   0.1    2.7e-34  117.9   0.1    1.5  1  DUF3336          Domain of unknown function (DUF3336)
    1.3e-15   58.1   0.4    3.3e-15   56.8   0.1    1.8  2  Patatin          Patatin-like phospholipase
  ------ inclusion threshold ------
      0.048   13.4   0.5      0.096   12.4   0.5    1.4  1  Gly-zipper_YMGG  YMGG-like Gly-zipper


Domain annotation for each model (and alignments):
>> DUF3336  Domain of unknown function (DUF3336)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.9   0.1   4.4e-38   2.7e-34       3     137 ..      37     179 ..      35     180 .. 0.94

  Alignments for each domain:
  == domain 1  score: 117.9 bits;  conditional E-value: 4.4e-38
     DUF3336   3 awrgkrkklrkklrkattYeeWkeaAkeLDellgndeWkendes.yYdyklvkkvlkkLrklrekedlkellellrtclkrNfagienprLYsetyiGT 100
                 + r+ ++kl  +l +a+t+eeW+e+A +LDell+ d W++n++s +Ydy+l+ ++l+++  +re+ed+  l+++lr+ l+rN+++i++ +L++++y GT
  EEA20749.1  37 RSRSPKNKLSYALSTANTFEEWEETAFRLDELLSADLWRQNPTSkHYDYRLILQRLESILGARESEDILTLVSILRSGLVRNLGNITSTKLFNHAYAGT 135
                 5678899******************************************************************************************** PP

     DUF3336 101 KklieeYidevekalellaetkq.......lsaeekleffketr 137
                 K li++Yi++v  +++++++ ++        +++ kle++++tr
  EEA20749.1 136 KLLIDDYITHVALSIQYVTSLETipmhvsgFTSQAKLELLHDTR 179
                 ******************87766777888888899999988887 PP

>> Patatin  Patatin-like phospholipase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0      0.93   5.6e+03      59      88 ..      67     128 ..      47     140 .. 0.47
   2 !   56.8   0.1   5.5e-19   3.3e-15       1     172 [.     187     353 ..     187     381 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 0.93
     Patatin  59 nlllnkifdrdl................................lirelaanlaarlsgllg 88 
                 +ll+++ ++ ++                                l   l +nl +++s  l+
  EEA20749.1  67 ELLSADLWRQNPtskhydyrlilqrlesilgaresediltlvsiLRSGLVRNLGNITSTKLF 128
                 44444444444344444444444444444444444444433333333334444444444444 PP

  == domain 2  score: 56.8 bits;  conditional E-value: 5.5e-19
     Patatin   1 LvlsGGGsrgafslgalkaLkkelgerfdiisGtSaGAiialllalgrdpaalvddlrnlllnkifdrdl..................lirelaanlaa 81 
                 Lvl+GG + g+ +lg++kaL + +g  ++ii+Gt +GA++++l++   +     d+l ++l+++i                       ++ e+++  + 
  EEA20749.1 187 LVLQGGSVFGLCHLGVVKAL-HLRGLLPRIITGTATGALVGALVGVR-TE----DELLDFLDSDILEFCAfngesakgkskgnlvagtMQNERSRIGFG 279
                 8*******************.********************777665.33....5555555555555555555599*********************** PP

     Patatin  82 rlsgllgkgglfdaealrellrkvladktlkrlsarlgklpllkslftanqavpaittataatastanranglytedddddvdladavraS 172
                  l +++++g+++d  +l++ +r++++d+t++++ a+ +++                  + ++ as      +l+++ ++++v +++a++aS
  EEA20749.1 280 WLWRYFTEGNFLDESVLEDCVRTYVGDMTFEEAYAKTKRI-----------------LNITVAASGKGAFPNLLNYLTAPNVLIRSAALAS 353
                 ****************************************.................4555555555555666667777788888888887 PP

>> Gly-zipper_YMGG  YMGG-like Gly-zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.5   1.6e-05     0.096       9      22 ..     217     230 ..     214     235 .. 0.63

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 1.6e-05
                      XXXXXXXXXXXXXX CS
  Gly-zipper_YMGG   9 iGAaaGAvvGaliG 22 
                      +G+a+GA+vGal+G
       EEA20749.1 217 TGTATGALVGALVG 230
                      45666666666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (577 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       375  (0.0209158); expected 358.6 (0.02)
Passed bias filter:                      338  (0.0188521); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.22s 00:00:00.74 Elapsed: 00:00:00.38
# Mc/sec: 4582.86
//
Query:       EEA20750.1  [L=685]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.1e-05   22.8   2.3    0.00056   19.0   0.2    2.3  3  PhoD      PhoD-like phosphatase


Domain annotation for each model (and alignments):
>> PhoD  PhoD-like phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.0   0.2   3.1e-08   0.00056      18     100 ..     183     274 ..     156     285 .. 0.65
   2 ?   -3.8   0.1      0.28     5e+03     150     175 ..     361     386 ..     355     407 .. 0.73
   3 !    3.3   0.0    0.0019        34     248     283 ..     476     513 ..     460     560 .. 0.73

  Alignments for each domain:
  == domain 1  score: 19.0 bits;  conditional E-value: 3.1e-08
        PhoD  18 relaeeedlDlvlhlGDyiYeyg..pgeyase...aaelgrevepp........keivtladYReryaqyktdadlqaahaaapfivvwDDHEvaN 100
                  ++ e+  + +++  GD iY ++   ++  +e    +++ +    +          ++  + Y ++y + +  + +++a+ ++p i +wDDH + +
  EEA20750.1 183 LRVHEKRPFHVMIGGGDQIYNDNirVDGPLNEwtnIKNPIK----RqahdfsgeLRAECDEFYYKNYVRWYNQEPFKTANGQIPQINIWDDHDIID 274
                 344455588999999*******7542222221112222222....145557764344444558999**************************9987 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 0.28
        PhoD 150 feyGdladlflLDtRqyrrdqavsye 175
                 +++G+ +++  +D R+ r + +v+y 
  EEA20750.1 361 MRLGRRIAFAGVDARTERTRMQVNYP 386
                 57788888999999999999998776 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.0019
        PhoD 248 aeRerlleti....keakirnvVvLtGDvHaawandldyk 283
                 aeR++l++ +    ke+   ++ +L+GDvH a+ +++ y 
  EEA20750.1 476 AERRELIHRLqqlsKEHS-VRITILGGDVHLAALGRF-YS 513
                 677766555511114444.6777899******99998.33 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (685 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       313  (0.0174578); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 4836.57
//
Query:       EEA20751.1  [L=560]
Description: hypothetical protein PMAA_045740 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.4e-40  136.9   0.5      1e-39  136.5   0.5    1.2  1  Fungal_trans_2  Fungal specific transcription factor domain
    6.5e-05   23.0  11.1    0.00015   21.8  11.1    1.7  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
       0.46   10.1   4.0       0.67    9.6   4.0    1.1  1  PAP1            Transcription factor PAP1


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  136.5   0.5   1.7e-43     1e-39      27     375 ..     165     551 ..     145     560 .] 0.85

  Alignments for each domain:
  == domain 1  score: 136.5 bits;  conditional E-value: 1.7e-43
  Fungal_trans_2  27 vllplalsnk..allhallalsafhlqskgpkds..lereakrykslalkelqealaelsstls.rnekykdiLaaiLllcsie.issgdvsd.. 113
                     vl+ l   nk  al +++ a++ +h+q ++ + +     +++  + +a+ +++  l++++++ + r+    d++ a  llc+ + +++ ++++  
      EEA20751.1 165 VLVDLVAVNKypALRYSVTAVANAHQQLTYRPGQhdAFLSKRTARLKAIYNFRTQLENPTHHRKaRRVPPLDLFLANVLLCILDgVIDPNDESaa 259
                     666666666677**************99999988897789999*********************988889999999999*****98888877779 PP

  Fungal_trans_2 114 wrvhLeaatsliksrggs.kasssslsskarfllrifayldilssttlgrgpsfpseeyekllenkkeesdsgldplmGcsns......lillis 201
                     ++vh ++ +++++++++  ++ +++++  ++++l++fa++d+ +s+ +g++++f+++ ++++ ++         d ++G+ ++      ++ ++s
      EEA20751.1 260 CHVHYRGGRAILSQWKLHqQLLQRHKRGLPALMLSCFATMDLTYSLLTGEEQYFRDTTWAHFAGS---------DGWWGVLPPcdpfldIMRILS 345
                     ******************9999999999*************************************.........99******99999******** PP

  Fungal_trans_2 202 eisrLarekrsarkdseleplsileeaseleqrllswkprssdlepdldet.erassls...........................kdl...tel 265
                     +++rL+  ++s +++       + +e+++l  +l+ ++ +++ le+   +  +++ +l+                           +++   +++
      EEA20751.1 346 RLARLGHAVHSGSES-----ALFGDELEALTMALRGYATPMDGLETLFMGQqNDIFALKpsrntqtplsphllapmysykaqleldESWtvfCNA 435
                     ***************.....777777777777777555555555555443303344444667777777777888888899998889555678*** PP

  Fungal_trans_2 266 frlaaliylyrlvlglppsspevqelvkkllellellpsspvaiasLlWplFiaGceavdeddRdfvrrrleele.qsrlgnvrrarqvleevWr 359
                     +rl+ liy+yr++++l+ s+p+vq+++++ l ++++ + ++ + ++Ll+p++++G+++ + ++++  +  +++++   ++g+ + +  +l+ +W+
      EEA20751.1 436 YRLTGLIYIYRVFHRLDVSHPLVQQATSHGLRAICESRLKGKLAHCLLFPALVIGAHCRTAPQQKANLMAIRSTAaFLNFGSLKVMETFLRGLWA 530
                     **************************************66666********************************99999*************** PP

  Fungal_trans_2 360 rrd.....dgeekidWrdvme 375
                     r       ++e++ +W+++ +
      EEA20751.1 531 RVPlveeeQEEQSESWWECFT 551
                     ***554444555999***985 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8  11.1   2.5e-08   0.00015       2      35 ..      12      45 ..      11      50 .. 0.88

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 2.5e-08
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCT CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfyse 35
                +C+ C+ ++v C+ ++P+Cs+C + n  C++ + 
  EEA20751.1 12 SCWACKDRRVICNLQRPQCSRCTSENQVCEYGKL 45
                8*****************************5444 PP

>> PAP1  Transcription factor PAP1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   4.0   0.00011      0.67     125     185 ..      61     121 ..      35     139 .. 0.71

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00011
        PAP1 125 nsgtstssdSPsssseshqgq.lSScgTSPEPs...tqSPaakksketsstieeeevahttidge 185
                 +++   ss+SP+ s  s +gq + S+ TSP Ps   ++SP  +k +++   +e  +va  + +ge
  EEA20751.1  61 GQNVPVSSGSPTDSKYSVNGQlSPSTLTSPSPSfslSSSPLSSKRETS---LELVRVA-DEEEGE 121
                 45666789*************666999*****8333468877773333...3333333.333444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (560 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       429  (0.0239277); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 3816.06
//
Query:       EEA20752.1  [L=510]
Description: amino acid permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.6e-47  161.2  48.7    4.5e-47  160.8  48.7    1.0  1  AA_permease_2  Amino acid permease
      1e-24   87.0  44.2    1.4e-24   86.6  44.2    1.0  1  AA_permease    Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  160.8  48.7     5e-51   4.5e-47      15     425 .]      56     485 ..      39     485 .. 0.79

  Alignments for each domain:
  == domain 1  score: 160.8 bits;  conditional E-value: 5e-51
  AA_permease_2  15 ig..sgifvknlaasggpalilwvwiavligslavllvyaElssalprsgGiyvytkaafgkkva....flsawfnwfayvpvlasilsvaasyl. 103
                    +g   + +   +++ ggp++i+++wi+v ++  +v+l +aEl+s++p+s G y ++ ++ + +++    f+++w  +++ +  + s++  +as l 
     EEA20752.1  56 YGegGPLMS--AIYGGGPLSIFVGWIVVCVLDECVALSLAELASRWPTSAGPYYWSFQLVPQRAKvvlsFINGWVWLIGNWTITLSVNFGFASLLs 149
                    552133444..5999***************************999**************9777773334666666666666666565555666554 PP

  AA_permease_2 104 ..lnalgpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfssl.stetdt.ffpngwpg..vllg 193
                      +++ +pd+  n+w+ +li+ ai +  ++i+ +g + + +i +i++ ++ + +lii+i+l  + +d g ++ + s  +++ +  +gw g  ++ g
     EEA20752.1 150 gtISMYHPDWSANNWQLLLIFYAICLSSFVICTFGNRFLPMIDTICAAWTAISILIIMIAL-SVKADVGRHDVSyS-LGHYdTSLSGWGGftFFIG 243
                    44666788*******************************************7666666655.55556666655542.3333133358887556*** PP

  AA_permease_2 194 llivlwsfdGfesaanvseevkk..kdvpkaifigllivlvlyllvniaflgvvpddeianlsnlgsvaalffeavggkvvaiivvilial.sllg 286
                    ll ++++f+++ +++ ++ee  +   +vp ai +++ + ++ +l++ i +   +p+ e   l++  +++   f++v g+ +a++  i+++l + l+
     EEA20752.1 244 LLPAAYCFSAVGMISAMAEECSNavVKVPQAISLCVPVGGIAGLFFIIPICVTLPPLEDLILAPAAQALPYIFQQVMGSPGAGLGLIFLVLaITLF 339
                    ********************8885458*****9999999999999999999999996655555555555555555544433333333333325567 PP

  AA_permease_2 287 aintavigssrvlealardgvlP..rffakvn.kfgspiraiiltaivslillllfllassaaynfllsvsslgliisyllliigalilrkkrphl 379
                    + ++ ++++sr+ +a+ard +lP  + +a+vn + g p+ +++l+ +v+++l+l+ l +ss+a+++ +sv++++l isy+++i + +++++++ ++
     EEA20752.1 340 CSISITVAASRTTYAFARDEALPlsKLWAQVNsRLGVPVWSLVLVTVVQMLLGLINL-GSSSAFTAFVSVGVVALAISYAIPIGASVFHKRQEVNK 434
                    888999*******************************************99986665.579*******************************9999 PP

  AA_permease_2 380 krpgk.....ilvaiigalfllfllvalffppkgpatqssliytiiltval 425
                     r+        +v+i+++l++ f lv++++p++ p+t  s++y+ +++v++
     EEA20752.1 435 ARFNCgpvlgLVVNIVALLWIAFELVLFCMPSVLPVTAVSMNYAAVVFVGF 485
                    994444444589********************************9998875 PP

>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.6  44.2   1.6e-28   1.4e-24      20     461 ..      63     492 ..      60     502 .. 0.77

  Alignments for each domain:
  == domain 1  score: 86.6 bits;  conditional E-value: 1.6e-28
  AA_permease  20 gvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgp....elGfviGln.ylfswitvlaleltaasiliqfwelvtdlpk 112
                   +++  +Gpl++++++++++v   +v+lsl+e+a+  p s+g y+++ + + +     l+f  G+  +  +w ++l + ++ as l + +++++  ++
   EEA20752.1  63 MSAIYGGGPLSIFVGWIVVCVLDECVALSLAELASRWPTSAGPYYWSFQLVPQrakvVLSFINGWVwLIGNWTITLSVNFGFASLLSGTISMYHPDWS 160
                  578999********************************888888887666655111167777777744446777777777777777777666444444 PP

  AA_permease 113 awvt..gavflvvll...iinlvgvkvygeaefi.lalikiiaiiafiivgiillaggkpnkgagfrflgdngsifknnlppgfakeeegafknfisv 204
                  a  +   ++f+++ l   +i+++g+++   + +i +a+ +i ++i++i ++    ++++  ++     +++++++ +  l++       g f+ fi++
   EEA20752.1 161 ANNWqlLLIFYAICLssfVICTFGNRFLPMIDTIcAAWTAISILIIMIALS----VKADVGRH----DVSYSLGHYDTSLSGW------GGFTFFIGL 244
                  555587777777764222678888887777666645555555555555555....45544444....6788888777777777......778877777 PP

  AA_permease 205 fvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasaaspfvifikesgvsvlaplinaviltaals 302
                  +++++  f+  +++ ++a+E+++   ++P ai+  v   +i+ +++++ i +++p   + +l+ +a+a  +  if++  g+++++  +++++l+ +l+
   EEA20752.1 245 LPAAY-CFSAVGMISAMAEECSNAVVKVPQAISLCVPVGGIAGLFFIIPICVTLPPLEDLILAPAAQA--LPYIFQQVMGSPGAGLGLIFLVLAITLF 339
                  77665.588888999************************************************99999..99************************** PP

  AA_permease 303 sansslysasRvlyslakdglaP...kvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliilsylrfRkalkyq 397
                  +++s++++asR+ y++a+d+++P    ++++ s+ gvP+ +++l++++ +l+ l++  +++   +f+ ++++  ++  i + + i +++ f k  ++ 
   EEA20752.1 340 CSISITVAASRTTYAFARDEALPlskLWAQVNSRLGVPVWSLVLVTVVQMLLGLINLGSSS---AFTAFVSVGVVALAISYAIPIGASV-FHKRQEV- 432
                  *************************99999*******************999988766666...8888888877777777777777777.4444344. PP

  AA_permease 398 grsieelgfkaallplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfli 461
                      ++++f    +  +v++++a+l+i + ++ ++ +  ++ + +++++a ++++  +++  + 
   EEA20752.1 433 ----NKARFNCGPVLGLVVNIVALLWIAFELVLFCMPSVLPVTAVSMNYAAVVFVGFMAISAVW 492
                  ....555666666666666666666666666666666666666688888877776666554443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (510 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       869  (0.048469); expected 358.6 (0.02)
Passed bias filter:                      350  (0.0195214); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.30s 00:00:00.94 Elapsed: 00:00:00.46
# Mc/sec: 3340.02
//
Query:       EEA20753.1  [L=567]
Description: rhomboid family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.4e-24   86.0   6.3    2.4e-24   86.0   6.3    1.7  2  Rhomboid         Rhomboid family
  ------ inclusion threshold ------
      0.033   14.4   0.5      0.089   13.0   0.5    1.8  1  Myb_DNA-binding  Myb-like DNA-binding domain


Domain annotation for each model (and alignments):
>> Rhomboid  Rhomboid family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0      0.36   3.3e+03      71     114 ..     316     362 ..     300     371 .. 0.51
   2 !   86.0   6.3   2.7e-28   2.4e-24       9     147 ..     393     545 ..     387     548 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.36
                 -EESSHHHHHHHHHHHHHHHHCCCCGS----HC.......CCCCCCCC CS
    Rhomboid  71 plvGaSGaifgllgallvlvprnrkllrkliia....llllllfilln 114
                 p++G +  + gl+ +++ + ++ + ++++++ +      +++ +++ n
  EEA20753.1 316 PAFGVTLLVLGLCYYYA-ETYQPPVYYKRMWKDippaAATIMGLMATN 362
                 66777777777665553.333333333333333322344444444444 PP

  == domain 2  score: 86.0 bits;  conditional E-value: 2.7e-28
                 HHHHGGG--SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-S......-EESSHHHHHHHHHHHHHHHHCCCCGS----HC. CS
    Rhomboid   9 rlltsmflHagwlHllfNmlallvfGsplerrlGslrflllyllsglagsllsllfsaeses...plvGaSGaifgllgallvlvprnrkllrkliia. 103
                  ++ s+f+H  + Hll N+++l+++G +l +++G+ +fl lyl+sg++gsl+sl  +   ++    ++GaSGai+gl++a+++l+   +    +l+ + 
  EEA20753.1 393 SVVGSVFSHQQFKHLLTNTVILWLIGLRLHDEIGRGNFLSLYLASGVVGSLISLTSHVLLQRltvTSLGASGAIAGLVAAWCMLHSDDKLVPSFLPHDw 491
                 56789********************************************9999888888777777********************99999888888889 PP

                 ...........CCCCCCCCCCHHHCTSS..STTTHHHHHHHHHHHHHHHHHHCC CS
    Rhomboid 104 ........llllllfillnlvlgllpra..ggvsnlAHlgGllaGlllgllllr 147
                          ++l+++++++++  + p +  g+ +n+AHlgG  aG++++ll  +
  EEA20753.1 492 rdsisangSTVLAAIVAFEVFNLVSPFKvvGKLDNYAHLGGYFAGFVWALLYKS 545
                 9*******88999999999999888888999*****************988765 PP

>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.5   9.9e-06     0.089       6      24 ..     186     207 ..     185     208 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 9.9e-06
                      HHHHHHHHHHHHHHT...TCHH CS
  Myb_DNA-binding   6 eeEdelLleavkkhG...nrWk 24 
                      +eE+e+Ll++v+++G   + W+
       EEA20753.1 186 KEEEERLLQYVQELGpqsGHWN 207
                      7**************7444497 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (567 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       858  (0.0478554); expected 358.6 (0.02)
Passed bias filter:                      466  (0.0259914); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.26s 00:00:00.86 Elapsed: 00:00:00.43
# Mc/sec: 3967.89
//
Query:       EEA20754.1  [L=187]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
     0.0023   17.8   0.8     0.0044   16.9   0.8    1.4  1  Shugoshin_N  Shugoshin N-terminal coiled-coil region
  ------ inclusion threshold ------
       0.14   11.5   1.9        8.5    5.7   0.3    2.1  2  DUF4618      Domain of unknown function (DUF4618)


Domain annotation for each model (and alignments):
>> Shugoshin_N  Shugoshin N-terminal coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.8   4.9e-07    0.0044      17      45 .]      23      51 ..      22      51 .. 0.94

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 4.9e-07
  Shugoshin_N 17 salslkirelekevseLlsENlnLRelil 45
                 s+l +k++el++ +s+L + N +LR+ i+
   EEA20754.1 23 SSLYAKVSELRNSISHLTRSNEELRTYII 51
                 7899*********************9886 PP

>> DUF4618  Domain of unknown function (DUF4618)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.0    0.0016        14     204     231 ..      24      51 ..      18      54 .. 0.75
   2 ?    5.7   0.3   0.00095       8.5     187     217 ..      61      91 ..      56     103 .. 0.91

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0016
     DUF4618 204 eleeeipeLkaeveqLqaqaeepreviF 231
                  l  +++eL++++ +L ++ ee r +i 
  EEA20754.1  24 SLYAKVSELRNSISHLTRSNEELRTYII 51 
                 5667788888888888888888888775 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.00095
     DUF4618 187 enqvlkkeiekfrefieeleeeipeLkaeve 217
                 +n++l+ +++++ e ++ + e+i  Lk eve
  EEA20754.1  61 DNKELEAYVVENEEVMQAMAERIRLLKVEVE 91 
                 89***************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (187 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       846  (0.0471861); expected 358.6 (0.02)
Passed bias filter:                      600  (0.0334653); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 1325.19
//
Query:       EEA20755.1  [L=341]
Description: protein kinase activator (Mob2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.7e-50  171.3   0.0    1.4e-49  168.4   0.0    2.0  1  Mob1_phocein  Mob1/phocein family


Domain annotation for each model (and alignments):
>> Mob1_phocein  Mob1/phocein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  168.4   0.0   7.8e-54   1.4e-49       4     169 .]      81     299 ..      78     299 .. 0.95

  Alignments for each domain:
  == domain 1  score: 168.4 bits;  conditional E-value: 7.8e-54
                   xxxx.xxxxxxxxxxxxxxxxxxxxxxxx..........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Mob1_phocein   4 lgsg.dlkeavklPkgedlneWlavhvvd..........ffneinllygtisefcteqscptmsagpkyeYlwadeevkkpvklsApeYidllmdwi 89 
                   l+ + ++ +++++Pk+++l eWla+++v+          +++e+n++ g+   +c+e++cptmsag +++Y+w  +  ++++k+sAp++i+++ +wi
    EEA20755.1  81 LNVKgNFLTLCACPKNVELGEWLAHQIVEqyrllhgmlqVIQEVNTVNGY--PICNESTCPTMSAG-RLTYTWLVD--GRAAKISAPKFINRVEKWI 172
                   56666************************889988888888888888888..89***********9.8*******6..7999*************** PP

                   xxxxxx..............................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxx RF
  Mob1_phocein  90 esqlnd..............................................lfpskagspfpknflkvvkkilkrlfrvyaHiYihHfee.iaele 139
                    s+++d                                              + +  ++s fp++f+k+++ i+k++fr+yaH+Y+ H+ + + +++
    EEA20755.1 173 VSKIHDpvmfptdpvqgaphtfasgdvstppattpiaagptnlnaslttlagQDWIGKSSGFPPTFYKDCQGIMKQMFRCYAHLYHGHWLDpFWHIN 269
                   ****************************************************************************************9777***** PP

                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Mob1_phocein 140 leahlntcfkhfvlfvkeFkLidkkelepl 169
                    +++ln+cf hfv+++k++kL+++ke+ep+
    EEA20755.1 270 RHEMLNMCFVHFVTVAKYYKLVADKEMEPM 299
                   ****************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (341 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       346  (0.0192983); expected 358.6 (0.02)
Passed bias filter:                      266  (0.0148363); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.23s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2417.57
//
Query:       EEA20756.1  [L=444]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.8e-27   95.6   0.0    1.5e-26   93.2   0.0    2.1  1  Leo1      Leo1-like protein
  ------ inclusion threshold ------
      0.056   13.4   0.1       0.11   12.5   0.1    1.4  1  Caf4      CCR4-associated factor 4


Domain annotation for each model (and alignments):
>> Leo1  Leo1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.2   0.0   1.6e-30   1.5e-26       2     165 .]     120     288 ..     119     288 .. 0.89

  Alignments for each domain:
  == domain 1  score: 93.2 bits;  conditional E-value: 1.6e-30
        Leo1   2 lvklPnflsiepkpfdpetfeeeadeeaeeaeeserarkklkaentiRwRykedkgteikeSNArivrWsDGSlsLqlGse...vfdvtrkal...... 91 
                 ++ +Pnfls+e+++f pet+ +                 +++a + + wRy++ +++ + +SNAri++W+DGS++Lql+s+   ++ + +k+l      
  EEA20756.1 120 TMEIPNFLSLETEEFRPETYVA---------------PPYSTAATSLCWRYDP-NDQTSLQSNARIIQWEDGSFTLQLASNpkeQYRIASKPLaplnka 202
                 789*****************54...............578999**********.88***********************86666*************** PP

        Leo1  92 ......adsntyLvvsheaeevleaqgvitekltfrPa.sleseahrrltravakr.hkkk.....akktklivteeDpekekeeae 165
                        d +tyL+++ e+++v ++++++t++l+  P+   +++a++rl++++ ++ +        ++ +++i+ +eDpe++ ++ae
  EEA20756.1 203 gnydatLDTHTYLAAAAETASVFKITSHLTHQLKPLPTnAETDDAIQRLQENLLAAgR-GGkananGSGIAIIDIKEDPELAGKRAE 288
                 **************************************666699*****999877632.22245668999**********9988775 PP

>> Caf4  CCR4-associated factor 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.1   1.2e-05      0.11      15      40 ..     219     244 ..     211     255 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.2e-05
        Caf4  15 aDsattfkiLahLDeeryPLPidaak 40 
                 a++a  fki +hL ++  PLP +a  
  EEA20756.1 219 AETASVFKITSHLTHQLKPLPTNAET 244
                 889******************99865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (444 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       780  (0.0435049); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.29s 00:00:00.89 Elapsed: 00:00:00.45
# Mc/sec: 2952.43
//
Query:       EEA20757.1  [L=433]
Description: C6 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      6e-08   32.7   7.1      6e-08   32.7   7.1    1.8  2  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
       0.14   12.0   3.8        0.4   10.5   3.8    1.8  1  PADR1     PADR1 (NUC008) domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.7   7.1   6.7e-12     6e-08       2      37 ..      22      56 ..      21      59 .. 0.89
   2 ?   -3.4   0.8       1.2   1.1e+04      17      21 ..     367     370 ..     363     382 .. 0.47

  Alignments for each domain:
  == domain 1  score: 32.7 bits;  conditional E-value: 6.7e-12
                S-HHHHHCT---ST.SSSS-HHHHHCTHHHCCCCTCC CS
     Zn_clus  2 aCdnCrkkKvKCda.kkPaCsnCkklnleCtfysess 37
                aCd+Cr +K KC++ + + C++C + +l+C  ys ++
  EEA20757.1 22 ACDECRNRKLKCSGdQAG-CRRCMTQGLHCH-YSIQK 56
                9*************6666.************.98876 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 1.2
                 SSS-H CS
     Zn_clus  17 kPaCs 21 
                 k+ C 
  EEA20757.1 367 KE-CN 370
                 33.32 PP

>> PADR1  PADR1 (NUC008) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   3.8   4.5e-05       0.4      15      50 ..      22      57 ..      19      59 .. 0.95

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 4.5e-05
       PADR1 15 kCpeCkegqlvfdssgYkCtGnmsewtkCtfktkdp 50
                 C eC + +l++++++  C+  m++  +C ++ ++p
  EEA20757.1 22 ACDECRNRKLKCSGDQAGCRRCMTQGLHCHYSIQKP 57
                7*******************************9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (433 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       490  (0.02733); expected 358.6 (0.02)
Passed bias filter:                      248  (0.0138323); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.25s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2857.54
//
Query:       EEA20758.1  [L=196]
Description: peptidyl-tRNA hydrolase domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-18   66.4   1.1    2.9e-18   65.9   1.1    1.2  1  RF-1      RF-1 domain
  ------ inclusion threshold ------
      0.038   14.4   0.7       0.07   13.5   0.7    1.5  1  MRP-S28   Mitochondrial ribosomal subunit protein


Domain annotation for each model (and alignments):
>> RF-1  RF-1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.9   1.1   3.2e-22   2.9e-18       6     114 ..      57     187 ..      51     193 .. 0.78

  Alignments for each domain:
  == domain 1  score: 65.9 bits;  conditional E-value: 3.2e-22
                 E--GGGEEEEEE---SSSSSSGCSSSCEEEEEETTT.........................TEEEEEEECSSSHHHHHHHHHHHHHHHHHH...HHHHH CS
        RF-1   6 eidekdleidtfrssGaGGQnVNktesaVrlthlpt.........................gvivvecqeeRsqekNrekAlerLkaklke...kelee 76 
                 +i+++   i+++rssG+GGQnVNk++s+++l   p                          + +v++++e R+q +N e + e+L   ++e     +  
  EEA20758.1  57 SIPRNICAISFSRSSGPGGQNVNKVNSKATLKV-PLsallplvpsilhqnlrssryiadrtDALVIQSDEARKQSANVESCYEKLYRVVEEsarNVIPG 154
                 699999*************************44.33347777888999999*******999779*************************8866544556 PP

                 CCCCCHTTTTT-..S.-S---S.--ECEEEECGCTTEEEE CS
        RF-1  77 ekeeekkrrvkk.ekkkigtgs.sekiRtynkkpqsrvkd 114
                 e + e+++rv++ +k+     + +++i+t+++  +s  k+
  EEA20758.1 155 EPSVEQRDRVRDlKKA-----EtEARIKTKKM--HSAKKS 187
                 7788888888774444.....22346666555..334443 PP

>> MRP-S28  Mitochondrial ribosomal subunit protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.7   7.8e-06      0.07      23      94 ..      79     150 ..      63     193 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 7.8e-06
     MRP-S28  23 hpasrkvvlevkvadL.kleekqkhklklLagprynpe.tdviklsserfesaaqNkrylsdilekLlkeakdl 94 
                 ++ + k +l+v++++L +l +  +h+   L  +ry ++ td + + s+   +++ N +++ + l + ++e+ ++
  EEA20758.1  79 NKVNSKATLKVPLSALlPLVPSILHQ--NLRSSRYIADrTDALVIQSDEARKQSANVESCYEKLYRVVEESARN 150
                 677999*******9999999999996..7899***88769******************************9864 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (196 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       951  (0.0530426); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.43
# Mc/sec: 1359.61
//
Query:       EEA20759.1  [L=394]
Description: rRNA processing protein Utp6, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.6e-28   98.5   2.1    3.1e-28   97.7   0.7    2.1  2  U3_assoc_6  U3 small nucleolar RNA-associated protein 6
      8e-07   29.4   1.7     0.0016   19.1   0.2    3.4  3  TPR_14      Tetratricopeptide repeat
     0.0037   16.4   0.0     0.0065   15.6   0.0    1.4  1  NRDE-2      NRDE-2, necessary for RNA interference
  ------ inclusion threshold ------
      0.041   13.6   0.2      0.095   12.5   0.2    1.6  1  DUF1351     Protein of unknown function (DUF1351)
      0.068   13.1   0.6      0.068   13.1   0.6    2.0  2  Suf         Suppressor of forked protein (Suf)


Domain annotation for each model (and alignments):
>> U3_assoc_6  U3 small nucleolar RNA-associated protein 6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.7   0.7   8.7e-32   3.1e-28       1      71 [.      10      80 ..      10      90 .. 0.94
   2 ?   -1.4   0.0      0.72   2.6e+03      25      74 ..     155     204 ..     150     212 .. 0.72

  Alignments for each domain:
  == domain 1  score: 97.7 bits;  conditional E-value: 8.7e-32
  U3_assoc_6  1 LEqmlpeledleekglFtkeEikeIvkkrrkfEyklqrrgkkkedflkYieyElnLeklrkkRrkrlklkk 71
                LE+++pel+++e+kg+F+k+Ei++I+kkr++fE+k++ +g + +df++YieyE+nLe+lrkkR kr ++k 
  EEA20759.1 10 LEKAVPELKEYEQKGIFNKDEIRSIAKKRSDFEHKVNTPGVTESDFVRYIEYEMNLEALRKKRTKRFGIKA 80
                8*******************************************************************932 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.72
  U3_assoc_6  25 IvkkrrkfEyklqrrgkkkedflkYieyElnLeklrkkRrkrlklkkkks 74 
                 +++ r++f   l   +++ + +++Y + E+   + +  Rr+ l+l+++ +
  EEA20759.1 155 MTQARSYFQRGLRFCKSQRNIWVQYGRLECIYIAKLFARRRILGLDESGK 204
                 56777777777877788888899999999887777777777777744444 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0         5   1.8e+04      19      28 ..       5      14 ..       3      22 .. 0.61
   2 !   19.1   0.2   4.4e-07    0.0016       3      43 ..     106     146 ..     104     147 .. 0.95
   3 !    8.6   0.0    0.0011       3.8       9      44 .]     147     182 ..     143     182 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 5
      TPR_14 19 eAiallrral 28
                +A+ +l++a+
  EEA20759.1  5 KARFYLEKAV 14
                5666666664 PP

  == domain 2  score: 19.1 bits;  conditional E-value: 4.4e-07
      TPR_14   3 allalaeallalGdpdeAiallrralalaPddaeawlllaq 43 
                 ++ ++ e+++++  +++  +++ +al+l+P++a++w + a+
  EEA20759.1 106 LWIQYIEYCRRQKMYRRLSDVFSDALRLHPANADLWVYAAK 146
                 799*********************************99886 PP

  == domain 3  score: 8.6 bits;  conditional E-value: 0.0011
      TPR_14   9 eallalGdpdeAiallrralalaPddaeawlllaql 44 
                  a++   d  +A+ +++r l+ + +++ +w ++++l
  EEA20759.1 147 YAMEDHADMTQARSYFQRGLRFCKSQRNIWVQYGRL 182
                 45666778889**********************997 PP

>> NRDE-2  NRDE-2, necessary for RNA interference
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   1.8e-06    0.0065      46     137 ..      85     171 ..      36     182 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 1.8e-06
      NRDE-2  46 laeiklsilekAleknksnpdserLllelLklgseiwdseklakeWeellkenpnsvkLWreyldfrqsnfasfsvekvkelyekclrtlsa 137
                    + l il++A +k    p s  L +++++ +++    ++l++ ++++l+ +p + +LW    ++ +++ a   +++ ++ +++ lr  ++
  EEA20759.1  85 AGRRVLFILDRATRKL---PGSLGLWIQYIEYCRRQKMYRRLSDVFSDALRLHPANADLWVYAAKYAMEDHA--DMTQARSYFQRGLRFCKS 171
                 4556688*********...*************************************************9766..556777777777776665 PP

>> DUF1351  Protein of unknown function (DUF1351)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.2   2.6e-05     0.095     158     197 ..      27      67 ..       5      74 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 2.6e-05
     DUF1351 158 kkdre.elekakaeieekakafeleasaylrllkegkslsd 197
                 +kd+  +++k+++++e k++  + ++s+++r++++ ++l +
  EEA20759.1  27 NKDEIrSIAKKRSDFEHKVNTPGVTESDFVRYIEYEMNLEA 67 
                 3454459****************************999875 PP

>> Suf  Suppressor of forked protein (Suf)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.1      0.68   2.4e+03      89     106 ..       6      46 ..       3      70 .. 0.48
   2 ?   13.1   0.6   1.9e-05     0.068       4      76 ..     107     179 ..     105     181 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.68
         Suf  89 aRvlfekvvsklskeke.......................a 106
                 aR  +ek+v +l++ ++                        
  EEA20759.1   6 ARFYLEKAVPELKEYEQkgifnkdeirsiakkrsdfehkvN 46 
                 56666666666666654555555553333333333333330 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 1.9e-05
         Suf   4 wikymrasrRaeGikgaRkvFkkAR..kkprltyevyvasAllEyyiskdkkvAtkIFelGlKkFpedeefvlkY 76 
                 wi+y++ +rR +  +    vF++A   +  +    vy a   +E +   d   A+  F +Gl+  +++ +  ++Y
  EEA20759.1 107 WIQYIEYCRRQKMYRRLSDVFSDALrlHPANADLWVYAAKYAMEDH--ADMTQARSYFQRGLRFCKSQRNIWVQY 179
                 ************************6355556677789999999999..66667*********9988888877766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (394 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       588  (0.032796); expected 358.6 (0.02)
Passed bias filter:                      504  (0.0281109); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.39
# Mc/sec: 3034.45
//
Query:       EEA20760.1  [L=936]
Description: integral plasma membrane protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.8e-37  129.0   6.5    1.8e-37  129.0   6.5    2.8  3  Frag1     Frag1/DRAM/Sfk1 family


Domain annotation for each model (and alignments):
>> Frag1  Frag1/DRAM/Sfk1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  129.0   6.5   9.8e-42   1.8e-37       4     218 ..      18     224 ..      15     225 .. 0.97
   2 ?   -2.4   0.1      0.16   2.8e+03      57     100 ..     375     418 ..     335     421 .. 0.48
   3 ?    1.1   3.0     0.013   2.4e+02      79     169 ..     503     611 ..     484     672 .. 0.70

  Alignments for each domain:
  == domain 1  score: 129.0 bits;  conditional E-value: 9.8e-42
       Frag1   4 llpliafilwlgmliamlvcavvqgpvdyvfmh.keqf...lPyISd.igatnpeslffslalnlglflvilvallrfqrlpplatksernlnfaalvl 97 
                 ++ +++++++  +++ ++++ v ++++++v+++  +++   +P++S+ ig+++pe+++f+++++++++++++++ l+++   +  ++    l  + +++
  EEA20760.1  18 WISYAHTLFAALAFVGAFIVGVQLHYHKIVQNEhFGYPdewFPSVSAtIGDRYPERSVFQVFIAITSGPRFALVGLWYLMTARPGST----LPKVVAFT 112
                 788999*******************999**99989999******************************************9988888....99****** PP

       Frag1  98 gligalglllvsifstaeyhsvHlvgavvffvfgflyvllqtalyykmgrhyvwnkstisfrlkvvllilavvlailfgvffvrhkkkcgygayslsAi 196
                 gl+++l+++++++++++++h++H++++++++v++++++l + al+         + ++  ++++ vl+ l++ ++++++++f++hk ++ +gay+++A+
  EEA20760.1 113 GLFRTLTCGGWTYVTSTDDHDWHDIFMISYLVATLPWTLGCLALS---------PANRRAVKYRKVLASLFFGTLVPLIYYFIQHKVHKVAGAYTKYAF 202
                 ********************************************9.........89999**************************************** PP

       Frag1 197 fEWllafwfiiffltfsvDFyt 218
                 fEW+l+++ ++f+ ++++DF+ 
  EEA20760.1 203 FEWSLIIFDVGFDAVTALDFDA 224
                 ********************85 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.16
       Frag1  57 fslalnlglflvilvallrfqr....lpplatksernlnfaalvlgli 100
                  ++a+ l +  v+ +a+    +    ++p  + ++  +n + l+lg++
  EEA20760.1 375 SAFAIGLVMSSVAKFAF----QtnnpVWPIMNAENGGWNKFGLFLGVL 418
                 22222222222222222....123335555555555566666666655 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.013
       Frag1  79 lpplatksern..........lnfaalvlgligalglll..vsifstaeyhsvHlvgavvffvfgflyvllqtalyykmgrhy......vwnkstisfr 159
                 ++p    s++           l + + ++g+ g l++ +  +++     +  vH + a+ f  +++++v+l+ + ++ ++         v ++  ++++
  EEA20760.1 503 YNPRLAGSWTAfgigslgaavLTCYSHWFGFYGGLTIAFylMAVTPVLFASAVHHSPASTFGTGFCVWVFLTLFHVWVVAYAFvpggplVREHTDWLMT 601
                 666667777667777777777888888888888766554114555666677899999999999999999999888888876667777775555555555 PP

       Frag1 160 lkvvllilav 169
                 + ++++ + v
  EEA20760.1 602 ITMLCVGAGV 611
                 5555555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (936 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       503  (0.0280551); expected 358.6 (0.02)
Passed bias filter:                      286  (0.0159518); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.70u 0.31s 00:00:01.01 Elapsed: 00:00:00.51
# Mc/sec: 5492.57
//
Query:       EEA20761.1  [L=650]
Description: C6 transcription factor OefC [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.4e-67  227.4   0.1      3e-67  227.1   0.1    1.1  1  Fungal_trans_2  Fungal specific transcription factor domain
    2.5e-09   37.1  10.4    3.8e-09   36.5  10.4    1.3  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
       0.12   12.7   0.4       0.27   11.6   0.4    1.5  1  FinO_N          Fertility inhibition protein N terminal
       0.43   10.6   6.8        1.3    9.2   6.8    1.9  1  AT_hook         AT hook motif


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  227.1   0.1   6.8e-71     3e-67       1     383 [.     279     649 ..     279     650 .] 0.95

  Alignments for each domain:
  == domain 1  score: 227.1 bits;  conditional E-value: 6.8e-71
  Fungal_trans_2   1 elldyyldnvapllspvpessnpfrkvllplalsnkallhallalsafhlqskgpkdslereakrykslalkelqealaelsstls....rneky 91 
                     ++ld+++ +++++l+ +++ snpf+++llp+a+++++l+h+l++ls+ hl++++p+ + +++++++ ++a++ l+++++     ++    +    
      EEA20761.1 279 RFLDHFVFDFSRVLTLINDDSNPFKEILLPMATQHRGLMHSLMCLSGSHLSARDPEPRFKERKHYHFDRAITDLRDSINAAPVVEDpeepQLLVE 373
                     589***********************************************************************************998777778 PP

  Fungal_trans_2  92 kdiLaaiLllcsieissgd.vsdwrvhLeaatsliksrggskasssslsskarfllrifayldilssttlgrgpsfpseeyekllenkkeesdsg 185
                     + i+a++L+lc+  i++g+ +++ r+h++aa+ l+ ++++       +++  +f++++f+y+d+ +s+t+ ++ + + +  ++l +        +
      EEA20761.1 374 DPIIASTLALCLNTICEGEtSGEYRSHMDAARYLLLNQKPK------NEKFRQFIIEFFQYHDVSNSLTSLDRRPVQLTGDLRLPDF---VPHAQ 459
                     889999*************5556**************9999......9***********************9999999999999999...55566 PP

  Fungal_trans_2 186 ldplmGcsnslilliseisrLarekrsarkdseleplsileeaseleqrllswkprssdlepdldeterasslskdltelfrlaaliylyrlvlg 280
                         +G+ + l+ +isei+rL+ ++r ++++      + + +++ l +++ ++ + ++++ep++ ++ +++ +s    +l+r+++++ylyr+++ 
      EEA20761.1 460 AGTFLGIFDGLFNYISEITRLRDRIRVRHSE----GFEPAVDYQILSEAV-TIDSALRFWEPSYAPETPNWYAS----QLYRQSTWVYLYRTIRP 545
                     668****************************....888888888888877.6999999****************....***************99 PP

  Fungal_trans_2 281 lppsspevqelvkkllellellpsspvaiasLlWplFiaGceavdeddRdfvrrrleele.qsrlgnvrrarqvleevWrrrd.dgeekidWrdv 373
                       +s ++++++v+++l++l+llp++ +a + +l+plF +Gc+a  + +R+ +++ +++l  +s+l+n++ a++v+e vW+ +d + ee++dW+++
      EEA20761.1 546 SRSS-EKISQVVDDALKYLDLLPQDAGAYSIMLMPLFLIGCSAFLPRQRERIKQGFDALKeYSSLRNIEPALRVVERVWEVMDtKMEESWDWEKI 639
                     8887.**********************999999**************************************************87889******* PP

  Fungal_trans_2 374 mekkgwelll 383
                     +e++++++l+
      EEA20761.1 640 IEEMQMDFLI 649
                     ****999986 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.5  10.4   8.5e-13   3.8e-09       1      36 [.     203     238 ..     203     242 .. 0.93

  Alignments for each domain:
  == domain 1  score: 36.5 bits;  conditional E-value: 8.5e-13
                 SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus   1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfyses 36 
                 ++C++Cr++K KCd+ kPaC nC+k+ + C+ y+ +
  EEA20761.1 203 TGCITCRRRKKKCDETKPACLNCQKNAVVCEGYPPK 238
                 58*****************************99876 PP

>> FinO_N  Fertility inhibition protein N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.4     6e-05      0.27      12      50 ..     212     255 ..     205     258 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 6e-05
      FinO_N  12 kRktegtAPars...RkkiinvttPPk..WkvkkekLaekakre 50 
                 k+k + t Pa     +  ++    PPk  Wk  k+k+a+ + r 
  EEA20761.1 212 KKKCDETKPACLncqKNAVVCEGYPPKeiWKSGKQKMADAVRRS 255
                 677799999865553445666678**999**********99885 PP

>> AT_hook  AT hook motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   6.8   0.00028       1.3       1      11 [.     176     186 ..     176     188 .. 0.89

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00028
     AT_hook   1 kRkRGRPrKaa 11 
                 +RkRGRPrK++
  EEA20761.1 176 PRKRGRPRKHP 186
                 7********86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (650 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       687  (0.0383178); expected 358.6 (0.02)
Passed bias filter:                      486  (0.0271069); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.44
# Mc/sec: 4459.09
//
Query:       EEA20762.1  [L=545]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.2e-38  131.6  52.7    3.5e-36  124.9  33.4    2.0  2  MFS_1          Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  124.9  33.4   1.9e-40   3.5e-36       4     352 ..      75     480 ..      72     481 .. 0.88
   2 !   20.9  11.3   7.9e-09   0.00014      45     165 ..     384     527 ..     381     535 .. 0.78

  Alignments for each domain:
  == domain 1  score: 124.9 bits;  conditional E-value: 1.9e-40
       MFS_1   4 aaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrr.vlllglllfalglllllfasslw.lllvlrvlqGlgag 100
                 ++fl +++ ++l++ lp   a+d g+s++ i +  ++y+l+++   l++G+++d +G r   l+ ++l+ ++  +++ + s+    l+++r +qG++ +
  EEA20762.1  75 ITFLGSFTTGLLTIGLP-QTAQDIGLSEDLILWPSSVYSLASGSCLLLAGSIADVVGNRIiNLIGCFLVGCFV-TACGL-SQTGiQLIIFRTMQGVAVS 170
                 78999************.799***************************************5555555555555.66665.888888************* PP

       MFS_1 101 alfpagaaliadwfpk.eergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 + +p+++a++++ +p  ++r+  +++l+    +G+  g +lgg+++  +gWr+ +yi ++++l +fv+ ++ lp+++++ + k    ++          
  EEA20762.1 171 LCLPTSVAIVSQAVPAgRRRNISYSVLGFVQPAGFSAGLVLGGVMVNTIGWRYGYYISGGLTLALFVVSIWSLPADRRDASGKINLARLrteidwiggi 269
                 *******************************************************************999***99999999999999999********* PP

       MFS_1 189 .................................................kgtgpaplvpawkallkdpvlw.illialllfffgfsglltllplylqev 237
                                                                  ++ g+ +l+p   +l+++ v+  ++l+++++++ +++ +  +  l++q+ 
  EEA20762.1 270 iscaclamlsyilaaltndvnniktpgniamlvicvllmpvfilweqrqERLGKPALIP--NSLWRNSVFTnVCLMVMFSWA-VINVMELYCSLFFQKI 365
                 ******************************************99998877777777777..778888877556777777775.7777999999999*** PP

       MFS_1 238 lglsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllll..vlvliGfglgfvfpsllalasdlappeea 334
                  gls +++a+l +    ++g i +l +g l++r+++    + + ll + a l++a++ v   + ++ +  + +l  + + + f+ +l ++sd++p++ +
  EEA20762.1 366 QGLS-AFQASLRILPNVVIGSICQLTTGLLVHRISAFYLVVGSTLLSAGAPLLMAVIKVE-WPYWYDAffAQALSPISADILFTVALLVISDVFPQRTQ 462
                 ****.8***************************887555555555555555555555555.333333245555599999999***************** PP

       MFS_1 335 gtasglfntagslggalg 352
                 + a ++fnt++++g +lg
  EEA20762.1 463 ALAGAVFNTVSQFGNSLG 480
                 ***************998 PP

  == domain 2  score: 20.9 bits;  conditional E-value: 7.9e-09
       MFS_1  45 aavaslplGrlsdrfGrrrvlllglllfalg.lllllfa...sslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgp 138
                  ++ +l +G l+ r+ +  +l++g +l+++g  ll++++    ++w   +++ +l+ + a +lf++++ +i+d+fp++ +++a +++++ +++G  lg 
  EEA20762.1 384 GSICQLTTGLLVHRI-SAFYLVVGSTLLSAGaPLLMAVIkveWPYWyDAFFAQALSPISADILFTVALLVISDVFPQRTQALAGAVFNTVSQFGNSLGL 481
                 57899999*******.55555555555555513333322557788856*************************************************** PP

       MFS_1 139 llggllasslg...................Wravfyilaivsllaf 165
                  + ++++s                      +ra f+++ + ++ af
  EEA20762.1 482 TVMAVISSVTTkhaaaspadyespgpllagYRAGFWAAFAWMMCAF 527
                 ****999776688888888888888888886666666666555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (545 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       575  (0.0320709); expected 358.6 (0.02)
Passed bias filter:                      238  (0.0132746); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.64u 0.32s 00:00:00.96 Elapsed: 00:00:00.52
# Mc/sec: 3141.49
//
Query:       EEA20763.1  [L=422]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-17   62.7   0.9    3.4e-17   62.7   0.9    1.5  2  CDH-cyt   Cytochrome domain of cellobiose dehydrogenase


Domain annotation for each model (and alignments):
>> CDH-cyt  Cytochrome domain of cellobiose dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.7   0.9   1.9e-21   3.4e-17      19     169 ..      34     179 ..      21     191 .. 0.79
   2 ?   -3.9   0.0      0.51   9.1e+03      49      70 ..     231     253 ..     224     256 .. 0.78

  Alignments for each domain:
  == domain 1  score: 62.7 bits;  conditional E-value: 1.9e-21
                 -EEEEEEB-CCC.TS--SEEEEEEEEE-GCS--EEEEESSSSSCTSEEEEEEEE..TTEEEEEEEEBSSSSS-EE--SS-.EEEEEE.EEE-SSEEEEE CS
     CDH-cyt  19 gftfgialPeda.ttdatefigqlvaplsakagWaGislggsMtnnlLlvaWpn..gnevvtSfrlatgyasPevytgda.kltqlsgtsvnathftlt 113
                 +f+f     +++ +++ + ++ + +a+ s+k gW+G++lg +M+++l+++++ +  +++ +tS r a+g+++P+v++++  ++++l+  +v+++++ + 
  EEA20763.1  34 DFCFAATTQQNTsSDSHDVYLTI-SATPSKKGGWTGVGLGREMKGALMFIVYEDqeSKSLITSIRSASGHVMPSVVKDAHeQVSVLH-ATVSDDKYLAQ 130
                 67777777777766667777777.4444348**********************9878899****************87768******.9********** PP

                 EEEET-SEEEETTEEEE--TTTEEEEEEEEESS--BSTTSCCCB-----SEEEEEE CS
     CDH-cyt 114 frCqgClsweqggtsgsastssnlvlgwAqskkaptnpaspdstlsqHdngfgqfg 169
                 f C  C+s e  + +      + +   +A +k+++   a++ s+l+qH+ +  ++g
  EEA20763.1 131 FVCYSCWSPE-VEVN------GLSPYIFAGNKEQAFYGADKYSSLTQHEFNGKIWG 179
                 ********95.2222......55567899999999999999999999987444443 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 0.51
                 --EEEEESSSSSC.TSEEEEEEE CS
     CDH-cyt  49 agWaGislggsMt.nnlLlvaWp 70 
                 + ++G+ + gsM+ +++L+ a+ 
  EEA20763.1 231 VSFMGLYFVGSMAiRSPLIRAFK 253
                 67889999999988888888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (422 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       705  (0.0393218); expected 358.6 (0.02)
Passed bias filter:                      533  (0.0297284); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.32s 00:00:00.97 Elapsed: 00:00:00.54
# Mc/sec: 2331.67
//
Query:       EEA20764.1  [L=105]
Description: hypothetical protein PMAA_045870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (105 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       355  (0.0198003); expected 358.6 (0.02)
Passed bias filter:                      230  (0.0128284); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.30s 00:00:00.72 Elapsed: 00:00:00.47
# Mc/sec: 668.37
//
Query:       EEA20765.1  [L=1015]
Description: cleavage and polyadenylylation specificity factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.7e-64  216.2   0.0    6.9e-64  214.8   0.0    1.7  1  Lactamase_B_6  Metallo-beta-lactamase superfamily domain
    2.8e-46  157.8   0.1    2.8e-46  157.8   0.1    2.2  3  CPSF100_C      Cleavage and polyadenylation factor 2 C-termin
    5.3e-14   52.5   0.0    1.6e-13   50.9   0.0    1.9  1  Beta-Casp      Beta-Casp domain
    4.8e-11   42.4   0.0    1.2e-10   41.2   0.0    1.7  1  RMMBL          Zn-dependent metallo-hydrolase RNA specificity
  ------ inclusion threshold ------
       0.02   14.9   0.1      0.061   13.3   0.1    1.8  1  Lactamase_B    Metallo-beta-lactamase superfamily
      0.067   12.7   0.1       0.44   10.0   0.0    2.0  2  Lactamase_B_2  Beta-lactamase superfamily domain


Domain annotation for each model (and alignments):
>> Lactamase_B_6  Metallo-beta-lactamase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  214.8   0.0   2.3e-67   6.9e-64       1     193 []      21     260 ..      21     260 .. 0.91

  Alignments for each domain:
  == domain 1  score: 214.8 bits;  conditional E-value: 2.3e-67
  Lactamase_B_6   1 lLeld.nvkiLlDvGwdeskvslesalkelekviptvdliLLshatlehlGayallyakfksklllnipvyatlpvvkLGrvslldlyaskgllgp 95 
                    +Lel+ ++kiL+DvGwde+++     l+elek+ipt++l+LL+hat++h+Ga+a++++ f+  l+++ipvyat pv+ LGr++l+d y+s+ l ++
     EEA20765.1  21 ILELEgGIKILVDVGWDETFDV--LELAELEKHIPTLSLVLLTHATISHIGAFAHCCKIFP--LFTQIPVYATGPVISLGRTLLQDMYTSAPLAAT 112
                    7999978***********9654..4799*****************************9995..99***************************9997 PP

  Lactamase_B_6  96 e.dseel........................................eledideafdkiktlkYsQkl.elkskl....dgltitaynaGhtlGGt 145
                    +  ++++                                        + e+i+++f+ i++lkYsQ++ +l s++    dglt+tay+aGht+GGt
     EEA20765.1 113 FlPKASIselgastsaasaavatasaegddqsskklgttgrillqppTGEEIARYFSLIHPLKYSQPHsPLCSPFspplDGLTLTAYSAGHTVGGT 208
                    7323333667999999999********9999999999888887777777*****************7768999877778***************** PP

  Lactamase_B_6 146 iWkiskesekivYavdwnhakeshLngaalldssg....kvleqllrptali 193
                    iW+i++++e+ivYavdwn+a+e++++gaa++++sg    +v+eql++ptali
     EEA20765.1 209 IWHIQHGMESIVYAVDWNQARENVVAGAAWFGGSGtsgtEVIEQLRKPTALI 260
                    *******************************988878889**********98 PP

>> CPSF100_C  Cleavage and polyadenylation factor 2 C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.2       1.9   5.8e+03      61      61 ..     564     564 ..     512     597 .. 0.41
   2 ?   -4.1   0.2       5.2   1.6e+04      45      62 ..     655     672 ..     647     688 .. 0.47
   3 !  157.8   0.1   9.4e-50   2.8e-46       1     170 []     837    1009 ..     837    1009 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1.9
   CPSF100_C  61 k 61 
                  
  EEA20765.1 564 G 564
                 1 PP

  == domain 2  score: -4.1 bits;  conditional E-value: 5.2
   CPSF100_C  45 eeeeeeeeeeeeeaskkq 62 
                 e+ee++++++e  ++ + 
  EEA20765.1 655 EREEADAQQRESGPQSEM 672
                 222222222222222233 PP

  == domain 3  score: 157.8 bits;  conditional E-value: 9.4e-50
   CPSF100_C    1 VkLsdsLvksLkwqkveglevatvtgeleieeeaeeaeeeekeeeeeeeeeeeeeeeaskkqkl......aeksekeaseeeseekkeslptldvlp 91  
                  VkLs++Lv++Lkwq+v++l+v+++t++l++ e               + e+e   e+ skkqkl      a ++ ++  +++s +k++++p+ldvlp
  EEA20765.1  837 VKLSNNLVRRLKWQHVRSLGVVALTAQLRPPEI-------------VSVEDEV-TESISKKQKLietepdAVSTPQDGVHDSSISKADAYPILDVLP 919 
                  8***************************94332.............1111111.1122222222233333344556667788889999********* PP

   CPSF100_C   92 ankas.vrsaaqplfvGdlrLadLkkallssgikAEFrgeGtLvidgaVaVrKsakGrieiegvvle..........tfyeVrkaiYegl 170 
                  a+ a+ +rs+a+pl+vGdlrLadL+k+++++g+kAEFrgeGtL+idg+VaVrKs++G ie+e++v++          +f++V+++iYegl
  EEA20765.1  920 ASIAAgTRSMARPLHVGDLRLADLRKLMIAAGYKAEFRGEGTLLIDGMVAVRKSSTGTIEVEAAVQSsasdrrgqagSFLAVKRKIYEGL 1009
                  ****************************************************************************************87 PP

>> Beta-Casp  Beta-Casp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.9   0.0   5.4e-17   1.6e-13       1      99 [.     306     459 ..     306     462 .. 0.92

  Alignments for each domain:
  == domain 1  score: 50.9 bits;  conditional E-value: 5.4e-17
                 HHHHHHHH..HCTT...TT.....S-S-EEEEE-HHHHHHHHHGGGGGGE-SHH.....HHH..H...HH............................. CS
   Beta-Casp   1 aqellylLeelwkekk.le.....dlklpiyldsplaskatevYkeyaeveaks.lewmesk..ke.eln............................. 60 
                 ++el y Le++w++ + +       +k+++yl+++ a++++++        a+s lewm++   +e e+                              
  EEA20765.1 306 VLELSYALEHAWRDAAdSAdsedvFKKAELYLAGRKAHSTMRL--------ARSmLEWMDEGivREfEAVeggdaaavrghkttdsqnrnagvtrdkqg 396
                 68***********988555999964449***************........9*********99876654489*************************** PP

                 ........................HS-SSEEEEES-TTSSSSHHHHHHHHHTTSTTSEEEESS CS
   Beta-Casp  61 ........................sskgpkvilassgmlegGrsrellkklledprntvilvg 99 
                                          +  pkvi+as+++l++G+s+e ++ l++ ++n+++l++
  EEA20765.1 397 tklgpftlkhlkiveqkrklekvlADGIPKVIIASDTSLDWGYSKETFRTLAQGSQNLILLTE 459
                 *******************9999977789********************************97 PP

>> RMMBL  Zn-dependent metallo-hydrolase RNA specificity domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.2   0.0   3.9e-14   1.2e-10       1      53 [.     749     806 ..     749     820 .. 0.82

  Alignments for each domain:
  == domain 1  score: 41.2 bits;  conditional E-value: 3.9e-14
       RMMBL   1 tipvkarieeidfSgHadknellelirklkprnvilvHGeeeatsalarllk.....e 53 
                 t+ v ari+++d+ g +dk++l +li++++pr++ilv G +e+t++la+ ++     +
  EEA20765.1 749 TVTVSARIAFVDYMGLHDKRSLEMLIPLIQPRKLILVGGMKEETASLAAECRhllagK 806
                 689************************************************6444441 PP

>> Lactamase_B  Metallo-beta-lactamase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.1     2e-05     0.061      14      67 ..      26      77 ..      16      91 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 2e-05
                 TTCEEEES--SCHHHHHHHHHHHHHTSGGGGEEEEE-SBSSHHHHTTGGGCTTH CS
  Lactamase_B 14 dggviLiDtGtsteaaraalelaalglkpkdvdavilTHlHlDHiGglgglvea 67
                 +g  iL+D G+++ ++ +   la l++ +  ++ v+lTH+ + HiG+ ++ ++ 
   EEA20765.1 26 GGIKILVDVGWDETFDVLE--LAELEKHIPTLSLVLLTHATISHIGAFAHCCKI 77
                 56789************97..8************************98886665 PP

>> Lactamase_B_2  Beta-lactamase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00015      0.44       3      67 ..      30      93 ..      29     112 .. 0.77
   2 ?   -1.5   0.0       0.5   1.5e+03      95     155 ..     186     254 ..     146     261 .. 0.67

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00015
                   EEES--TT..HHHHHTCGGS--SSS--..SEEEEE-SS--HHHHGGGGCCCC....C--EEEEEEEEHHHH CS
  Lactamase_B_2  3 iLiDagpd..lrqqalralqPvelrdelppidaVllthaHyDHlaglltlre....lrpkklplyapkgvl 67
                   iL+D g+d  +   +l      el +++p + +Vlltha + H+  + ++ +    +  +++p+ya+  v+
     EEA20765.1 30 ILVDVGWDetFDVLELA-----ELEKHIPTLSLVLLTHATISHIGAFAHCCKifplF--TQIPVYATGPVI 93
                   999*****642222222.....35788*****************9999998887644..349999987765 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.5
                    EEEECSTTEEEEEEEE-EE--C..TCCE-TTTSEEEEEECTTEE......EEEESS-S---HHHHHHHC CS
  Lactamase_B_2  95 sfelgdggleitatparhksgr..rldrnagdtlGlriegggkr......vyyigDtgyipeeigerlg 155
                    +f++   gl++ta  a h+ g    + ++ ++ + +++++++ r      +++ g++g+   e+ e+l+
     EEA20765.1 186 PFSPPLDGLTLTAYSAGHTVGGtiWHIQHGMESIVYAVDWNQARenvvagAAWFGGSGTSGTEVIEQLR 254
                    555555589999999999999866666777777777777666665565565566666655555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1015 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       513  (0.0286129); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.79u 0.31s 00:00:01.10 Elapsed: 00:00:00.51
# Mc/sec: 6003.48
//
Query:       EEA20766.1  [L=494]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-14   53.8   0.0    2.5e-08   34.4   0.0    3.6  3  Ank_2     Ankyrin repeats (3 copies)
    1.1e-12   48.2   0.0    0.00013   22.4   0.0    5.8  6  Ank_4     Ankyrin repeats (many copies)
    4.6e-12   45.0   0.0      0.087   13.4   0.0    7.0  7  Ank_3     Ankyrin repeat
    1.2e-09   38.1   0.2        1.4    9.5   0.0    5.0  5  Ank       Ankyrin repeat
    2.8e-08   33.8   0.3       0.33   11.3   0.0    6.2  7  Ank_5     Ankyrin repeats (many copies)


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.6   0.0    0.0033        12      29      70 ..     192     242 ..     151     255 .. 0.64
   2 !    8.5   0.0   0.00084         3      31      80 ..     280     334 ..     276     338 .. 0.77
   3 !   34.4   0.0   6.9e-12   2.5e-08      10      78 ..     358     441 ..     345     443 .. 0.83

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.0033
       Ank_2  29 aLhyAakngnleivklLleh....ad......ndgrtpLhyAarsghleivk 70 
                 +L +Aa+ g+  i k L+++     +          ++L  Aar+g+ e+v+
  EEA20766.1 192 PLDVAASVGDQAIHKVLIANkcpmSNprgffeP-WSNILTTAARCGNVEAVE 242
                 666666666655556666644554222233211.224666666666666665 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00084
       Ank_2  31 hyAakngnleivklLleh...ad.ndgrtpLhyAarsghleivklLlek.gadin 80 
                 h Aa++g++ei+klL +    ++ ++       A+++g+  +v+++l++  +d++
  EEA20766.1 280 HSAARGGHVEILKLLDARikdITaEKRFHSFVEAIKFGQCHTVDWFLDQgRIDLQ 334
                 7899999999999999866452246677889999999999999999977345655 PP

  == domain 3  score: 34.4 bits;  conditional E-value: 6.9e-12
       Ank_2  10 lelvklLl.egadpn...k.ngktaLhyAakngnleivklLleh.ad.........ndgrtpLhyAarsghleivklLlekgad 78 
                 +++v+lLl  ga+pn   + +g+t L+ A ++++ e+++lL+eh ad         +  + pL +A++ ++  +v+lLl kga+
  EEA20766.1 358 PQMVRLLLeRGANPNevfSpTGRTLLQRALEKDDSETARLLVEHgADvsssgygptCRKKPPLSIAIKRKNAPMVQLLLRKGAN 441
                 469******9****976648***********************994443445555577999******99999*******99986 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0      0.21   7.6e+02      16      44 ..     170     198 ..     156     215 .. 0.72
   2 ?   -0.6   0.0      0.61   2.2e+03      38      51 ..     228     241 ..     190     242 .. 0.61
   3 !    6.0   0.0    0.0054        19      40      54 ..     280     294 ..     263     294 .. 0.92
   4 ?    0.1   0.0      0.37   1.3e+03      42      55 .]     313     326 ..     307     339 .. 0.74
   5 !   15.5   0.0   5.3e-06     0.019      13      45 ..     357     389 ..     346     392 .. 0.88
   6 !   22.4   0.0   3.7e-08   0.00013       1      55 []     379     436 ..     379     436 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.21
       Ank_4  16 lvrlLlekgadinaqdnrsGetalhiAak 44 
                  +++L+++g +++ ++ +  + +l+ Aa+
  EEA20766.1 170 ELQSLFDQGLQPDLWTEELILRPLDVAAS 198
                 58899999999888866667777776665 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.61
       Ank_4  38 alhiAakrgnveil 51 
                  l  Aa+ gnve++
  EEA20766.1 228 ILTTAARCGNVEAV 241
                 56667888888877 PP

  == domain 3  score: 6.0 bits;  conditional E-value: 0.0054
       Ank_4  40 hiAakrgnveilklL 54 
                 h Aa++g+veilklL
  EEA20766.1 280 HSAARGGHVEILKLL 294
                 8999999******98 PP

  == domain 4  score: 0.1 bits;  conditional E-value: 0.37
       Ank_4  42 AakrgnveilklLl 55 
                 A+k+g+ + + ++l
  EEA20766.1 313 AIKFGQCHTVDWFL 326
                 67777777777775 PP

  == domain 5  score: 15.5 bits;  conditional E-value: 5.3e-06
       Ank_4  13 rlelvrlLlekgadinaq.dnrsGetalhiAakr 45 
                 r ++vrlLle+ga++n++ ++  G+t+l++A+ +
  EEA20766.1 357 RPQMVRLLLERGANPNEVfSPT-GRTLLQRALEK 389
                 679***************7777.********965 PP

  == domain 6  score: 22.4 bits;  conditional E-value: 3.7e-08
       Ank_4   1 eltaLhyaaisgrlelvrlLlekgadinaqdnrsGet.....alhiAakrgnveilklLl 55 
                 ++t+L +a ++ + e++rlL+e+gad+  +  ++G t     +l iA+kr n  +++lLl
  EEA20766.1 379 GRTLLQRALEKDDSETARLLVEHGADVSSS--GYGPTcrkkpPLSIAIKRKNAPMVQLLL 436
                 5899**********************8776..5544444445*****************8 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0       0.3   1.1e+03       5      19 ..     228     242 ..     226     243 .. 0.84
   2 ?   -1.4   0.0       1.6   5.9e+03      12      25 ..     265     280 ..     261     283 .. 0.64
   3 ?    2.6   0.0     0.082   2.9e+02       7      23 ..     280     295 ..     279     303 .. 0.74
   4 ?    2.3   0.0       0.1   3.6e+02       7      29 ..     311     333 ..     307     335 .. 0.83
   5 !    6.7   0.0    0.0037        13      14      30 ..     357     372 ..     347     373 .. 0.89
   6 !   13.4   0.0   2.4e-05     0.087       2      30 ..     379     406 ..     378     407 .. 0.95
   7 !    8.6   0.0   0.00093       3.3       4      28 ..     418     441 ..     416     442 .. 0.92

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.3
       Ank_3   5 pLhlAarsgnleivk 19 
                 +L +Aar+gn+e v+
  EEA20766.1 228 ILTTAARCGNVEAVE 242
                 6889******99775 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 1.6
       Ank_3  12 sgnl.eivkfLle.nk 25 
                  ++  +i  +L+e ++
  EEA20766.1 265 LNKSrDIWLALIEtHH 280
                 444427999***9444 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.082
       Ank_3   7 hlAarsgnleivkfLle 23 
                 h Aar g++e +  Ll+
  EEA20766.1 280 HSAARGGHVE-ILKLLD 295
                 88********.555555 PP

  == domain 4  score: 2.3 bits;  conditional E-value: 0.1
       Ank_3   7 hlAarsgnleivkfLlenkgadv 29 
                  +A+++g +  v+++l++  +d+
  EEA20766.1 311 VEAIKFGQCHTVDWFLDQGRIDL 333
                 58999999988******888886 PP

  == domain 5  score: 6.7 bits;  conditional E-value: 0.0037
       Ank_3  14 nleivkfLlenkgadvn 30 
                 ++ +v++Lle +ga++n
  EEA20766.1 357 RPQMVRLLLE-RGANPN 372
                 5679******.9****9 PP

  == domain 6  score: 13.4 bits;  conditional E-value: 2.4e-05
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G+t+L +A++ ++ e +++L+e +gadv 
  EEA20766.1 379 GRTLLQRALEKDDSETARLLVE-HGADVS 406
                 9*********************.9***95 PP

  == domain 7  score: 8.6 bits;  conditional E-value: 0.00093
       Ank_3   4 tpLhlAarsgnleivkfLlenkgad 28 
                  pL +A++  n ++v++Ll+ kga+
  EEA20766.1 418 PPLSIAIKRKNAPMVQLLLR-KGAN 441
                 59******************.8986 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0       3.7   1.3e+04       5      22 ..     192     209 ..     192     214 .. 0.73
   2 !    5.7   0.1    0.0063        23       7      21 ..     280     294 ..     279     304 .. 0.81
   3 !    9.0   0.0   0.00056         2      13      28 ..     356     372 ..     344     374 .. 0.71
   4 !    7.1   0.0    0.0022       7.8       2      28 ..     379     406 ..     378     408 .. 0.90
   5 !    9.5   0.0   0.00038       1.4       5      26 ..     419     441 ..     418     444 .. 0.94

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 3.7
                 HHHHHHHHTTHHHHHHHH CS
         Ank   5 PLHlAatngkkriiklLL 22 
                 PL +Aa+ g+  i k L+
  EEA20766.1 192 PLDVAASVGDQAIHKVLI 209
                 788888777777888887 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.0063
                 HHHHHHTTHHHHHHH CS
         Ank   7 HlAatngkkriiklL 21 
                 H Aa++g+++i+klL
  EEA20766.1 280 HSAARGGHVEILKLL 294
                 89***********65 PP

  == domain 3  score: 9.0 bits;  conditional E-value: 0.00056
                 TTHHHHHHHH.TTTSTT CS
         Ank  13 gkkriiklLL.hGAnln 28 
                   +++++lLL +GAn+n
  EEA20766.1 356 RRPQMVRLLLeRGANPN 372
                 3489******99****9 PP

  == domain 4  score: 7.1 bits;  conditional E-value: 0.0022
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnln 28 
                 G+T L +A   ++ + ++lL+ hGA++ 
  EEA20766.1 379 GRTLLQRALEKDDSETARLLVeHGADVS 406
                 899****9988889************85 PP

  == domain 5  score: 9.5 bits;  conditional E-value: 0.00038
                 HHHHHHHHTTHHHHHHHH.TTTS CS
         Ank   5 PLHlAatngkkriiklLL.hGAn 26 
                 PL +A+ ++++ +++lLL +GAn
  EEA20766.1 419 PLSIAIKRKNAPMVQLLLrKGAN 441
                 899***9***********88**9 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.12   4.3e+02      17      40 ..     190     213 ..     174     220 .. 0.76
   2 ?    2.7   0.0     0.048   1.7e+02      16      33 ..     225     242 ..     208     243 .. 0.79
   3 ?    1.2   0.0      0.13   4.8e+02      21      35 ..     280     294 ..     263     297 .. 0.91
   4 ?   -2.0   0.0       1.4   5.2e+03      16      48 ..     306     339 ..     300     344 .. 0.77
   5 !    7.2   0.0    0.0018       6.3      25      44 ..     354     373 ..     354     386 .. 0.79
   6 ?    0.7   0.0       0.2     7e+02      15      42 ..     378     405 ..     374     408 .. 0.85
   7 !   11.3   0.0   9.1e-05      0.33      19      42 ..     419     442 ..     413     450 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.12
       Ank_5  17 ntpLhvAakygaadvvrlLlarga 40 
                   pL vAa+ g + + ++L+a+ +
  EEA20766.1 190 LRPLDVAASVGDQAIHKVLIANKC 213
                 389*********999999997665 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.048
       Ank_5  16 gntpLhvAakygaadvvr 33 
                 + ++L +Aa++g+ + v+
  EEA20766.1 225 WSNILTTAARCGNVEAVE 242
                 23999**********997 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.13
       Ank_5  21 hvAakygaadvvrlL 35 
                 h Aa++g+ ++++lL
  EEA20766.1 280 HSAARGGHVEILKLL 294
                 88*********9987 PP

  == domain 4  score: -2.0 bits;  conditional E-value: 1.4
       Ank_5  16 gntpLhvAakygaadvvrlLl.argadlnltdsr 48 
                 +++ +  A+k g +  v ++l   + dl +++ +
  EEA20766.1 306 RFHSFVEAIKFGQCHTVDWFLdQGRIDLQMRTTH 339
                 5566666888888888999999999999998865 PP

  == domain 5  score: 7.2 bits;  conditional E-value: 0.0018
       Ank_5  25 kygaadvvrlLlargadlnl 44 
                 +++++++vrlLl+rga++n 
  EEA20766.1 354 WRRRPQMVRLLLERGANPNE 373
                 67899************995 PP

  == domain 6  score: 0.7 bits;  conditional E-value: 0.2
       Ank_5  15 ggntpLhvAakygaadvvrlLlargadl 42 
                  g t L  A ++  ++ +rlL+++gad 
  EEA20766.1 378 TGRTLLQRALEKDDSETARLLVEHGADV 405
                 566888889999999999*******996 PP

  == domain 7  score: 11.3 bits;  conditional E-value: 9.1e-05
       Ank_5  19 pLhvAakygaadvvrlLlargadl 42 
                 pL +A+k+ +a++v+lLl  ga++
  EEA20766.1 419 PLSIAIKRKNAPMVQLLLRKGANR 442
                 89****************666554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (494 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      450  (0.025099); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.50
# Mc/sec: 2946.74
//
Query:       EEA20767.1  [L=218]
Description: hypothetical protein PMAA_045900 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (218 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       747  (0.0416643); expected 358.6 (0.02)
Passed bias filter:                      482  (0.0268838); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 1455.82
//
Query:       EEA20768.1  [L=449]
Description: camp independent regulatory protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.2e-45  154.4   0.5    8.8e-38  130.2   0.1    2.1  2  Gti1_Pac2  Gti1/Pac2 family


Domain annotation for each model (and alignments):
>> Gti1_Pac2  Gti1/Pac2 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  130.2   0.1   4.9e-42   8.8e-38       1     101 [.       3     102 ..       3     113 .. 0.87
   2 !   24.8   0.0   1.1e-09   1.9e-05     135     180 ..      99     145 ..      88     146 .. 0.76

  Alignments for each domain:
  == domain 1  score: 130.2 bits;  conditional E-value: 4.9e-42
                 SEES---SHHHHHHHHHHHHTTSS---SS---HHHHHHHSSTTEEEEEEHHHH--SS---S--B---EEETTEEEEEB--------------------- CS
   Gti1_Pac2   1 tfkgyiettkdalllieavlegilkrvtrRlkekErkeliksGsvFvfeeeesgikRWTDGvsWSpSrilgnfLvYreldkkrakkkkkkkkkkskest 99 
                 t++g ++t +da++l+ea++ g+l+rv+rRl+ekEr+  iksGsvFv++e+e+g++RWTDG sWS Sr++g+fL+Yre++ kr    ++++++k+  s 
  EEA20768.1   3 TYHGLVRTPADAIILFEACRLGLLPRVQRRLSEKERQ-AIKSGSVFVWDEREAGMRRWTDGKSWSASRVSGSFLTYREMEGKRGGGVSTSRSEKTPDSR 100
                 8************************************.*****************************************99987766666555544443 PP

                 -- CS
   Gti1_Pac2 100 kk 101
                  +
  EEA20768.1 101 GN 102
                 33 PP

  == domain 2  score: 24.8 bits;  conditional E-value: 1.1e-09
                 --------------------------EEEEEEEE.EETTTEEEEEEE CS
   Gti1_Pac2 135 kslekdserslvgsltdsykfkkdgLvKkTisvt.lkgkelhlisYy 180
                 ++ ++d +r+ +++  d y++k dgL+K+++s+t   g++lhlisYy
  EEA20768.1  99 SRGNSDDDRDGSEDGPDGYRYKPDGLMKQSFSITtSAGQHLHLISYY 145
                 444556677777777888**************98467899******* PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (449 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       291  (0.0162307); expected 358.6 (0.02)
Passed bias filter:                      161  (0.00897987); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.25s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 3232.58
//
Query:       EEA20769.1  [L=105]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.037   14.1   2.2      0.037   14.1   2.2    1.5  1  LTP_2     Probable lipid transfer


Domain annotation for each model (and alignments):
>> LTP_2  Probable lipid transfer
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   2.2   2.1e-06     0.037      27      69 ..      17      61 ..       5      67 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 2.1e-06
       LTP_2 27 lpclvskcyve..kkatpskeCCkalkkavksevaClCalvtskl 69
                +p l +kc+v+  +++  +++CC++l  ++    +C    + ++l
  EEA20769.1 17 VPALSCKCFVNgnMDNGRTQSCCNQLHGVFRYGNDCAASSISEHL 61
                677889**9997678999***************999877777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (105 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       384  (0.0214178); expected 358.6 (0.02)
Passed bias filter:                      192  (0.0107089); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.24s 00:00:00.62 Elapsed: 00:00:00.40
# Mc/sec: 794.42
//
Query:       EEA20770.1  [L=206]
Description: NADH-quinone oxidoreductase Pst2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.3e-08   33.9   0.0      3e-08   33.6   0.0    1.2  1  FMN_red       NADPH-dependent FMN reductase
    0.00011   22.0   0.0    0.00013   21.8   0.0    1.1  1  Flavodoxin_2  Flavodoxin-like fold
    0.00081   19.6   0.0      0.056   13.7   0.0    2.3  1  Flavodoxin_1  Flavodoxin
  ------ inclusion threshold ------
      0.057   13.6   0.0       0.11   12.8   0.0    1.4  1  Flavodoxin_5  Flavodoxin domain


Domain annotation for each model (and alignments):
>> FMN_red  NADPH-dependent FMN reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.6   0.0   6.6e-12     3e-08      17     145 ..      18     144 ..       4     149 .. 0.80

  Alignments for each domain:
  == domain 1  score: 33.6 bits;  conditional E-value: 6.6e-12
                 HHHHHHHHCCT-T.T-CEEEEETTTS.--...---HCHGHTCGGSHHHHHHHHHHHH-SCEEEEEEECTTCE-HHHHHHHHCHT-.SSCHCCTT-EE.E CS
     FMN_red  17 rklaewaaealkeagaevelidladlilpc.alcdkdlesegqtsddvaellekiaaadaliivtPeYngsysgllKnalDrlsrtrgkkelrgKpv.a 113
                  klae+ ++ +++ag ++++ ++a+  lp  +l + +     ++s    + +++i++  a++++ P+  g+++++ K+++Dr++ ++      gK++ +
  EEA20770.1  18 LKLAEAEKAGIEAAGGKADIYQIAET-LPEdVLAKMHA---PPKSNYPVATIDTIKDYNAVLFGIPTRYGNFPAQWKAFWDRTGGIWAAGGYWGKYAgL 112
                 567777788888889999*******8.66644444444...3577778999**********************************99888888888825 PP

                 EEEE-SSTTTTHHHHHHHHHHHHHTT-EEEEC CS
     FMN_red 114 lvavgggrrgglraeeqlrqvlaelgaivvpr 145
                 +v++g    g + ++ ++++ la++g i+vp 
  EEA20770.1 113 FVSTGTLGGGQESTCLAAMSTLAHHGFIYVPL 144
                 55666666666778999******999999985 PP

>> Flavodoxin_2  Flavodoxin-like fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   0.0   2.8e-08   0.00013      19     136 ..      19     118 ..       4     148 .. 0.71

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 2.8e-08
                   CHHHHHHHHHCCCTTTEEEEEEHHCC.T-----CCCCHCC.HHHHTTCHHHHHHHHHHHHCSSEEEEEEE-BTTB--HHHHHHHHHHS-TTTSCEET CS
  Flavodoxin_2  19 alaqafvealekagphevtvrdLyad.flpvlttrdlaak.layeekpadveseqiekllaadaivlqfPlwwfgvPailKgwiDrvltagfafyte 113
                   +la+a  +++e+ag  + ++  ++++ +  vl       k +a+++ +    +  i+ +++  a++++ P  + ++Pa+ K++ Dr    g      
    EEA20770.1  19 KLAEAEKAGIEAAG-GKADIYQIAETlPEDVLA------KmHAPPK-SNYPVAT-IDTIKDYNAVLFGIPTRYGNFPAQWKAFWDRT--GGIWA--- 101
                   67777778888888.777777777764444444......4345555.3333344.489****************************5..45422... PP

                   TCSSCCCCTTTTSEEEEEEEESS CS
  Flavodoxin_2 114 eggegrgggLkgkkalvivttGg 136
                          gg  gk a + v+tG 
    EEA20770.1 102 ------AGGYWGKYAGLFVSTGT 118
                   ......25677888888888876 PP

>> Flavodoxin_1  Flavodoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.7   0.0   1.2e-05     0.056       1      64 [.       8      88 ..       8     103 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.2e-05
                  EEEETSSSHHHHHHHHHHHHHHHTTTEEEEEEEEGTTSC..................GGGGGTHSEEEEEEEEETTTBEEGG CS
  Flavodoxin_1  1 ilYgSetGnteklAkqlaeelgehgfnadvvslsdydes..................lseieeealllvvtsTfgnGdppen 64
                  il++S+ G+  klA++ + +++++g +ad++++++   +                  ++ i++++ +l++++T + G +p +
    EEA20770.1  8 ILFYSMHGHILKLAEAEKAGIEAAGGKADIYQIAETLPEdvlakmhappksnypvatIDTIKDYNAVLFGIPTRY-GNFPAQ 88
                  89*****************************99987655456666666666666667777777777777777655.666654 PP

>> Flavodoxin_5  Flavodoxin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   2.4e-05      0.11      13      67 ..      39      94 ..      36      99 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 2.4e-05
  Flavodoxin_5 13 kiaeriaeelreegelvdvedve.kesedlesydavvigasvyygkllpelakFve 67
                  +iae++ e + ++++    ++   +  + +++y+av++g + +yg+++ + ++F +
    EEA20770.1 39 QIAETLPEDVLAKMHAPPKSNYPvATIDTIKDYNAVLFGIPTRYGNFPAQWKAFWD 94
                  67777777777777776666644246679********************9999976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (206 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       352  (0.019633); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1382.65
//
Query:       EEA20771.1  [L=551]
Description: amino acid permease [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.9e-64  218.1  44.7    2.2e-64  217.8  44.7    1.0  1  AA_permease_2  Amino acid permease
    1.3e-22   80.1  38.8    1.7e-22   79.7  38.8    1.1  1  AA_permease    Amino acid permease
  ------ inclusion threshold ------
      0.077   13.6   0.1       0.38   11.4   0.1    2.3  1  Renin_r        Renin receptor-like protein
       0.86    9.5   0.0       0.86    9.5   0.0    4.1  4  DUF2721        Protein of unknown function (DUF2721)


Domain annotation for each model (and alignments):
>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  217.8  44.7     5e-68   2.2e-64       1     424 [.      55     506 ..      55     509 .. 0.86

  Alignments for each domain:
  == domain 1  score: 217.8 bits;  conditional E-value: 5e-68
  AA_permease_2   1 lsllsafalvigsvigsgifvkn...laasggpalilwvwiavligslavllvyaEl.ssalprsgGiyvytkaaf.gkkva...flsawfnwfay 88 
                    +s +s++  +i+++  +g+++++    +a+ggpa+++w w++  ++ ++v+   aEl s+  p+ gG+y +tk++  +++va   ++ +w+n++++
     EEA20771.1  55 FSRWSTVSYAISILGVLGSVPATftfPLAAGGPAAVVWCWFIGSCMAMCVGSSVAELvSA-YPTAGGMYFVTKHVVpKEQVAifaWIQGWCNLLGQ 149
                    68899999999999888888888888899***********9999999**********877.***************444555777*********** PP

  AA_permease_2  89 vpvlasilsvaasyllnalgp..........dlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfss 174
                     ++++s+++ + ++ll  ++           ++ ++  +t+l+ ia+l +  +i+++ +k++ +i  + + ++il +  i i+++++++ +  +s 
     EEA20771.1 150 TAGVSSVAYTVSQMLLACVSMnstyessgrySYSPTAAQTVLVSIALLCVMGIICSLTTKTLHRIILWFAPVNILAT--IGICTAILYLTPEKQSA 243
                    ***************99886556788888888888899************************************755..66777777777777763 PP

  AA_permease_2 175 lstetdtffpngwpgv.........llgllivlwsfdGfesaanvseevkk..kdvpkaifigllivlvlyllvniaflgvvpddeianlsnlgsv 259
                    +     ++f+++ +g+         llg+l v+w+++ +++ +++see        pkai  ++++++++++l+n+++ ++++d     +s++g +
     EEA20771.1 244 K-----WVFTTVTDGSgwgskslsfLLGFLSVTWTMTDYDGTTHMSEETHDaaIQGPKAIRTAVVVSGIFGWLLNVSMCFCINDLDAVLTSPTGMP 334
                    3.....344443333222223334499*********************6654459*****************************888777787777 PP

  AA_permease_2 260 aalffeavggkvvaiivvilialsllgaintavigssrvlealardgvlP..rffakvn.kfgspiraiiltaivslillllfllassaaynflls 352
                    aa  f ++gg+++ ++++++++l+ ++ +++a+++ +r+ +a+ard +lP  +++ak+n k+++p++a+++++ +s++l l+  ++s++  +++++
     EEA20771.1 335 AAQIFLNAGGRTGGTVMWFFVILVQFFTGCSAMLADTRMTYAFARDEALPfsKYLAKINeKTHTPVNAVWFVVFFSTLLNLIA-IGSTETATAIFN 429
                    7777777799******************************************************************9987655.567999****** PP

  AA_permease_2 353 vsslgliisyllliigalilrkkrphl......krpgkilvaiigalfllfllvalffppkgpatqssliytiiltva 424
                    v++ +l isy+ +i++  i+r++ +        +r+g ++v++i++ +++f+  +lffpp +p t  +++y+i + ++
     EEA20771.1 430 VTAPALDISYISVILAHRIYRRRVRFIegpytlGRWG-PPVNWISIAWVVFISLILFFPPTRPITAANMNYAICVAAF 506
                    *********************9988663332223344.79********************************776665 PP

>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.7  38.8   3.7e-26   1.7e-22      21     460 ..      80     513 ..      62     523 .. 0.77

  Alignments for each domain:
  == domain 1  score: 79.7 bits;  conditional E-value: 3.7e-26
  AA_permease  21 vvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgpelGfviGlnylfswitvlaleltaasiliqfwelvtdlpkawvt.. 116
                  + l+++Gp++++ ++ ++  + ++v+ s++e+++++p +gg y+  ++++ +e     +++  ++ +++ ++++  ++++++ +  + +  ++  t  
   EEA20771.1  80 FPLAAGGPAAVVWCWFIGSCMAMCVGSSVAELVSAYPTAGGMYFVTKHVVPKEQVAIFAWIQGWCNLLGQTAGVSSVAYTVSQM--LLACVSMNSTye 175
                  67899**********************************************998888888855555555555555555555555..444444444445 PP

  AA_permease 117 .................gavflvvlliinlvgvkvygeaefilalikiiaiiafiivg.iillaggkpnkgagfrflgdngsifknnlppgfakeeeg 196
                                   ++ +l+v+ ii+ +  k   ++ +++a++ i+a i+  i++ i +l+ +k++++  f+ ++d ++              ++
   EEA20771.1 176 ssgrysysptaaqtvlvSIALLCVMGIICSLTTKTLHRIILWFAPVNILATIG--ICTaILYLTPEKQSAKWVFTTVTDGSG-----W--------GS 258
                  55555666666666998888999*****************************9..566355666666666635666655555.....2........33 PP

  AA_permease 197 afknfisvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasaaspfvifikesgvsvlaplina 294
                    ++f+ +f  v  ++t +  ++ +++E+ d + + Pkai+ +v+  +if  l+ +++ +++++ d  l++ +     p   ++ ++g +  ++++ +
   EEA20771.1 259 KSLSFLLGFLSVTWTMTDYDGTTHMSEETHDAAIQGPKAIRTAVVVSGIFGWLLNVSMCFCINDLDAVLTSPTG---MPAAQIFLNAGGRTGGTVMWF 353
                  3699**************************************************************99999555...457778888899999999999 PP

  AA_permease 295 viltaalssansslysasRvlyslakdglaP..kvlkkv.skrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliilsylr 389
                  ++++  ++++ s++ + +R+ y++a+d+++P  k+l+k+ +k + P++a+ ++ ++s l+ l+a  +++  ++++++ +++a +  i ++++il++  
   EEA20771.1 354 FVILVQFFTGCSAMLADTRMTYAFARDEALPfsKYLAKInEKTHTPVNAVWFVVFFSTLLNLIAIGSTE--TATAIF-NVTAPALDISYISVILAHRI 448
                  9999999**************************7777762699**********************9999..777777.55555555679999999998 PP

  AA_permease 390 fRkalkyqgrsieelgfkaallplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfl 460
                  +R+  +  +  +  lg   + +p   ++ +a +++i lil++ +  +   + +++++a  +aa++ ++ + 
   EEA20771.1 449 YRRRVRFIEGPY-TLG---RWGPPVNWISIAWVVFISLILFFPPTRP--ITAANMNYAICVAAFIAIFSLS 513
                  999966666644.333...5566666666666666666666653333..2225555555555555544433 PP

>> Renin_r  Renin receptor-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1   8.4e-05      0.38      55      86 ..     212     243 ..     204     251 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 8.4e-05
     Renin_r  55 FniiLwlvvvlvlaliaivvalasmdPgrDSi 86 
                   iiLw+  v +la+i i+ a++ + P++ S 
  EEA20771.1 212 HRIILWFAPVNILATIGICTAILYLTPEKQSA 243
                 579**************************996 PP

>> DUF2721  Protein of unknown function (DUF2721)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.0   0.00019      0.86      46     114 ..      38     107 ..      21     115 .. 0.83
   2 ?    1.7   2.5     0.049   2.2e+02      91     113 ..     181     203 ..     149     243 .. 0.52
   3 ?   -2.4   0.1       0.9     4e+03     101     124 ..     352     375 ..     337     379 .. 0.65
   4 ?   -0.0   1.4      0.17   7.6e+02      70     109 ..     470     512 ..     445     515 .. 0.75

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00019
     DUF2721  46 deelakeikn.lrrRarlirrailllvlsallvvlvvlllflsallsldlsllaailfvlalllllvsll 114
                 de+l ++i    + R +  r++ +++++s+l v+ +v + f   l +   + ++   f+ ++++++v++ 
  EEA20771.1  38 DERLLARIGYkQELRREFSRWSTVSYAISILGVLGSVPATFTFPLAAGGPAAVVWCWFIGSCMAMCVGSS 107
                 4555566654266799**************************9999999999999999999999998875 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.049
     DUF2721  91 sldlsllaailfvlalllllvsl 113
                 s + + + ++l  +all++++ +
  EEA20771.1 181 SYSPTAAQTVLVSIALLCVMGII 203
                 33333344444444444433322 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 0.9
     DUF2721 101 lfvlalllllvslllflrEirlsl 124
                  f++ l+ +++++  +l+++r+++
  EEA20771.1 352 WFFVILVQFFTGCSAMLADTRMTY 375
                 444446666666666666666655 PP

  == domain 4  score: -0.0 bits;  conditional E-value: 0.17
     DUF2721  70 lvlsallvvlvvlllfl...sallsldlsllaailfvlallll 109
                 + +s++ vv+++l+lf+   + +++++++ ++ + +++a+++l
  EEA20771.1 470 NWISIAWVVFISLILFFpptRPITAANMNYAICVAAFIAIFSL 512
                 5689999999999999966556666666666666666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (551 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       715  (0.0398795); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.61u 0.31s 00:00:00.92 Elapsed: 00:00:00.47
# Mc/sec: 3545.63
//
Query:       EEA20772.1  [L=1004]
Description: Sec23/Sec24 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.7e-47  160.9   0.0    7.8e-47  159.9   0.0    1.5  1  Sec23_trunk     Sec23/Sec24 trunk domain
    4.9e-25   87.3   0.0    1.5e-24   85.8   0.0    1.8  2  Sec23_helical   Sec23/Sec24 helical domain
    8.8e-18   64.8   0.0    2.2e-17   63.5   0.0    1.7  2  Sec23_BS        Sec23/Sec24 beta-sandwich domain
    2.4e-16   59.5   6.2      6e-16   58.2   6.2    1.7  1  zf-Sec23_Sec24  Sec23/Sec24 zinc finger
    9.2e-06   25.5   0.0      2e-05   24.4   0.0    1.5  1  Gelsolin        Gelsolin repeat


Domain annotation for each model (and alignments):
>> Sec23_trunk  Sec23/Sec24 trunk domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  159.9   0.0   2.2e-50   7.8e-47       7     241 ..     370     612 ..     364     614 .. 0.91

  Alignments for each domain:
  == domain 1  score: 159.9 bits;  conditional E-value: 2.2e-50
                  EEEEE-SHHHHHHTHHHHHHHHHHHHC..TTSST..............STT-EEEEEEESSSEEEEETSTTSSSSEEEEECHTTSCCSSTSSSSSEET CS
  Sec23_trunk   7 lFviDvsleaikegelkalkeslkqsL..dllPe..............epralvglitfdsvvhffelkselrqpkelvvsdlqdvflpladrlLvpl 88 
                  lF+iDvs+e+ + g lk +++ + ++L  d   e               + +++g++tfd+ +hf++l   l++++++v++dl+++f+pl+++l+v++
   EEA20772.1 370 LFLIDVSQESANRGFLKGVCDGIVNALygD--EEeeqaegtetesrkvPEGSKIGIVTFDKEIHFYNLCARLDKAQMMVMTDLEEPFVPLSEGLFVDP 465
                  8**************************542..32357889999888877889********************************************** PP

                  TTTHHHHHHHHHHHHHHSTT-TTC-----HHHHHHHHHHHHCHCTS-EEEEEEESS---SSTTTSS-SBTTSCCTSSTTCHHCHSCSSSCHHHHHHHH CS
  Sec23_trunk  89 seseavledlLeelpemfavtagkrperalgpalkaavellkavetggkiivfvgslptvgaggklksredeslldidkekaklvkkadkfYkkLake 186
                   es+av+++lLe+lp++fa    k+pe+al p +ka+ ++l+  ++ggkii+   slpt+g+ gkl  +++++  d   e +kl+  ++  Yk+ a++
   EEA20772.1 466 YESKAVITSLLEQLPTLFARV--KSPESALLPTIKAGISALQ--SSGGKIICCLASLPTYGP-GKLVMKDKSQAPDG--E-NKLFAIDNPDYKAVASK 555
                  *********************..*******************..899***************.77777777766663..3.6688999999******* PP

                  HHHCTEEEEEEEEC..SS--SHHHHTHHHHTTT-EEEEETTTCCHHHHHHHHHHHHH CS
  Sec23_trunk 187 cvkqgisvDlFlfs..ldyvdlaelkqlaeltgGqvvlydsFsaekdasklkqdlkr 241
                  +++ g+ +D F+++    ++dl +++  a ++gG+ ++y++F++++d  kl+q+++ 
   EEA20772.1 556 LTEAGVGIDFFVAApgGSFMDLTTIGYTAAISGGECFFYPNFHSPRDLLKLSQEITH 612
                  ************983358***********************************9986 PP

>> Sec23_helical  Sec23/Sec24 helical domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.8   0.0   4.2e-28   1.5e-24       1      98 [.     715     811 ..     715     816 .. 0.95
   2 ?   -2.7   0.0       1.5   5.4e+03       3      24 ..     927     951 ..     926     979 .. 0.65

  Alignments for each domain:
  == domain 1  score: 85.8 bits;  conditional E-value: 4.2e-28
                    -HHHHHHHHHHHHHHHTTTS-HHHHHHHHHHHHHHHHHHHHHH-------------GGGTTHHHHHHHHHTSTTTS--TT--HHHHHHHHHHHHH- CS
  Sec23_helical   1 DqeavtvllakqaidkalesgladarealdtslvdllsayrkvgasgsspsqlqlpeslklLPlyilallKspafrggnsvpaDervfalslllsl 96 
                    Dq+av++++ak+a +ka +++l+d+r+++++++vd++s yrk+ +++++p+ql+lpe+lk++ +y+l+l+Ks+af+gg+++  D rv+ l++l+s 
     EEA20772.1 715 DQDAVVAIIAKEAASKAGDKTLKDIRASITEKTVDIFSGYRKNFSGSHPPGQLVLPENLKEFSMYMLGLIKSRAFKGGSETA-DRRVHDLRMLRSI 809
                    9***************************************************************************998887.**********998 PP

                    -H CS
  Sec23_helical  97 pv 98 
                     +
     EEA20772.1 810 GC 811
                    76 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 1.5
                    HHHHHHHHHHHHHHTT...TS-HHH CS
  Sec23_helical   3 eavtvllakqaidkal...esglad 24 
                    +avt+ la+q id a+    ++l +
     EEA20772.1 927 KAVTIQLARQGIDGAEyefARSLVE 951
                    6899999999999887655334444 PP

>> Sec23_BS  Sec23/Sec24 beta-sandwich domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.5   0.0   6.2e-21   2.2e-17       1      93 [.     619     701 ..     619     704 .. 0.94
   2 ?   -3.2   0.0       4.2   1.5e+04      29      63 ..     880     909 ..     873     933 .. 0.64

  Alignments for each domain:
  == domain 1  score: 63.5 bits;  conditional E-value: 6.2e-21
                 EEEEEEEEEE-TTEEEEEEESSSEECSTBESSEESECSESEEEEEEEETT--EEEEEEESSBTCTTSEEEEEEEEEEEETTSEEEEEEEEEEE CS
    Sec23_BS   1 gfnatlevrtSkelkvsgliGncvslsnvsekeiGeggtsewklcsldpdstlavyfdideklksgkqayiQfatlYthssgerrlRVttval 93 
                 g++a ++vr+S++l+vs ++Gn+ +++         g    ++++++d d++l+v f++d kl+ + +a++Q+a+lYt ++g+rr+R+++v  
  EEA20772.1 619 GYQALMKVRCSNGLQVSAYHGNFLQHT--------FGAD--LEIGTIDADKALGVLFSYDGKLDPKLDAHFQAALLYTAANGQRRVRCINVVA 701
                 79************************9........2555..89***********************************************975 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 4.2
                 BESSEESECSESEEEEEEEETT--EEEEEEESSBT CS
    Sec23_BS  29 vsekeiGeggtsewklcsldpdstlavyfdidekl 63 
                   e+ +G g t   +l +ldp+++    +d+   l
  EEA20772.1 880 LIEDLFGPGIT---SLQALDPNTSSLPVLDTH--L 909
                 55666777777...888888888877777773..3 PP

>> zf-Sec23_Sec24  Sec23/Sec24 zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.2   6.2   1.7e-19     6e-16       1      39 []     289     327 ..     289     327 .. 0.99

  Alignments for each domain:
  == domain 1  score: 58.2 bits;  conditional E-value: 1.7e-19
  zf-Sec23_Sec24   1 PirCrrCraylNpfckidfggkrwiCnfCnhknevppeY 39 
                     P+rCrrCr+y+Npf+++  gg++++Cn+C + n+vppeY
      EEA20772.1 289 PPRCRRCRTYINPFMTFRSGGNKFVCNMCTFPNDVPPEY 327
                     99************************************9 PP

>> Gelsolin  Gelsolin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4   0.0   5.4e-09     2e-05       4      45 ..     843     886 ..     841     917 .. 0.82

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 5.4e-09
                 EEEEBSSSGGGEETTSEEEEEESSEEEEEEHTT..SHHHHHHHH CS
    Gelsolin   4 lpkvvklsssslesgdcyLLdngftiflWiGke..ssqeeknfa 45 
                 +p+  ++s s +e+g++yL+dng+ + lW+ +   +++ e++f+
  EEA20772.1 843 VPPALRASFSRIEEGGAYLVDNGQSMLLWMHSFvsPNLIEDLFG 886
                 69999*************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1004 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       433  (0.0241508); expected 358.6 (0.02)
Passed bias filter:                      385  (0.0214736); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.76u 0.29s 00:00:01.05 Elapsed: 00:00:00.48
# Mc/sec: 6302.80
//
Query:       EEA20773.1  [L=194]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (194 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       539  (0.030063); expected 358.6 (0.02)
Passed bias filter:                      440  (0.0245412); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.42
# Mc/sec: 1392.66
//
Query:       EEA20774.1  [L=560]
Description: asparaginyl-tRNA synthetase Slm5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.9e-68  229.0   0.0    2.5e-65  220.6   0.0    2.1  1  tRNA-synt_2      tRNA synthetases class II (D, K and N)
    1.7e-06   27.9   0.0    3.1e-06   27.1   0.0    1.4  1  tRNA_anti-codon  OB-fold nucleic acid binding domain


Domain annotation for each model (and alignments):
>> tRNA-synt_2  tRNA synthetases class II (D, K and N)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  220.6   0.0   2.8e-69   2.5e-65       3     312 ..     150     553 ..     148     554 .. 0.91

  Alignments for each domain:
  == domain 1  score: 220.6 bits;  conditional E-value: 2.8e-69
                  CHHHHTHHHHCCSHHHHHHHHHHHHHHHHHHHHHHHT...T-EE----SEESS--SSSS--EEEEETTT.......T........EEE....-E-S-S CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xx........xxx....xxxxxx RF
  tRNA-synt_2   3 elrlknryldlrtekvskvlrlrstvtkavrkyleen...gfieietPiLsksdteegarlFkvksrek......ek........eff....aLtqsp 79 
                  +++++  +l+lrt+  s   r+rs+ + ++ +++ +    gfi++++P++++sd+e++++ F++  ++       +k        +ff    +Lt+s+
   EEA20774.1 150 DFLRQIPHLRLRTPFSSLLARFRSETIYQLGQVFRSVpqgGFIQVQPPLITSSDCEGAGETFTLSPQSSglpldsPKgseeleylHFFrnpkYLTVSS 247
                  6788999*********************999999875556************************888878888772256678778888********** PP

                  HHHHHHHHHCTHSEEEEEEEEE--S--BTTB-S-CEEEEEEEEET-SCHH.HHHHHHHHHHHHHHHHHHCSCCCCCHTTTTTS............... CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............... RF
  tRNA-synt_2  80 qlylellivagidrvfqiaraFRaEdsrtdrhlaEFtqieaemsfieeed.imqvleelikslvkevlessakdiefvirrns............... 161
                  ql+le++++  +++v++++++FRaE+s+t rhl+EF+++eae++f++e   +++++e li++l++++ +++  +     +r+                
   EEA20774.1 248 QLHLEAYAAE-LGNVWTLSPTFRAEKSKTPRHLSEFYMLEAEVNFTNELPaLLDLVEYLIRDLARRLYDTPVAQEVLSAKRTGesgldssddvqgilr 344
                  *******999.**************************************99****************999855444444444479************* PP

                  .......EE-SSS-EEEEHHHHHHHHHTS..............-SS--HHHHHHHHHHS--.SEEEEEEEBGGGSTTCBBBSTTS......TTBBSEE CS
                  .......xxxxxxxxxxxxxxxxxxxxxx..............xxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxx......xxxxxxx RF
  tRNA-synt_2 162 .......kdlkkpfkrltykeaieklnei..............gkdldkaderalvkkekn.epvfvtdfPaelkpFyarkeedd......kkltesy 231
                         ++   +++r+ty++aie l++               +++l++++e++ v++  n +pvfvtd+P+++kpFy+  +e        +++++ +
   EEA20774.1 345 rrwevllSET-ISWPRITYTQAIEMLQDAqanhgasfvyppswSEGLQTEHEKYIVDTIFNgVPVFVTDYPQKVKPFYMAPSEGAdaghpdQATVACF 441
                  ***9885443.35************9999***************************9754438****************99998889*********** PP

                  EEEETTE.EEEEEEEB--SHHHHHHHHHHCCHH..............................SSSGGGGHHHHHHHHCT--SEEEEEEEHHHHHHHH CS
                  xxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxx..............................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2 232 Dllingv.ElvgGslRiedpeeleeklkskgld..............................eeaeekfswylealeyGapphgGlglGldRlvmll 298
                  Dll++++ E+vgGslR+++  el  k+++ gl                                e+  +++wy +++++G+ phgG+glG+dRl+ +l
   EEA20774.1 442 DLLFPEIcEVVGGSLREHRLAELISKMREYGLIkqgpqssklmddnenehilalsknypylqpGETLGHLQWYADLRRWGSAPHGGFGLGFDRLLGYL 539
                  *****************************9998899999*************99999998877788889***************************** PP

                  CT-SSGGGCSSS-X CS
                  xxxxxxxxxxxxxx RF
  tRNA-synt_2 299 lgsesIrdviaFPk 312
                  +g  s rdv++FP+
   EEA20774.1 540 AGVGSLRDVVPFPR 553
                  *************8 PP

>> tRNA_anti-codon  OB-fold nucleic acid binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.1   0.0   3.4e-10   3.1e-06       2      74 ..      59     130 ..      58     132 .. 0.88

  Alignments for each domain:
  == domain 1  score: 27.1 bits;  conditional E-value: 3.4e-10
                      EEEEEEEEEEEEEETTEEEEEEEETT..EEEEEEEETHHHHHHHTTS-TTSEEEEEEEEEECTTS...SEEEEEEEEE CS
  tRNA_anti-codon   2 tvaGrvtsisdrsggkvifidlrDgt..griqvvlfreeatklaenlkeGdvvrvtGrvkrrpgg...elelkveeie 74 
                      t++G ++s+  r+ ++++f+++ Dg+   ++q++l++    ++a +l  G+ ++++G +k+ p g     el+ +ei+
       EEA20774.1  59 TLKGFIRSV--RKQKRFAFAEISDGStvKSLQAILTP----EQAADLSTGTAIEISGIWKACPAGkeqTHELQTSEIR 130
                      89*******..***************999********....*******************996665555666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (560 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       377  (0.0210274); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.43
# Mc/sec: 3884.14
//
Query:       EEA20775.1  [L=1099]
Description: RNA binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.8e-09   36.2   0.0    8.1e-09   35.2   0.0    1.6  1  RRM_1      RNA recognition motif. (a.k.a. RRM, RBD, or RNP do
  ------ inclusion threshold ------
      0.031   14.4   0.3      0.031   14.4   0.3    2.5  2  ApoLp-III  Apolipophorin-III precursor (apoLp-III)
      0.098   12.7   0.1       0.29   11.2   0.1    1.8  1  DUF1664    Protein of unknown function (DUF1664)


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.2   0.0   1.4e-12   8.1e-09       1      69 [.     730     799 ..     730     800 .. 0.96

  Alignments for each domain:
  == domain 1  score: 35.2 bits;  conditional E-value: 1.4e-12
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrel 69 
                 lf+gn+ ++vte+ ++e+F       ++ l+ d +tg++ gf++ +F s ++A++Al +l+g  ++g+ l
  EEA20775.1 730 LFMGNIGFEVTERVIEEVFASHFFSAKVHLPIDsSTGRHAGFGYARFLSDSSAKAALGRLQGVLIDGHSL 799
                 8********************888889**************************************99976 PP

>> ApoLp-III  Apolipophorin-III precursor (apoLp-III)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   1.0      0.13   7.7e+02      26      81 ..     264     319 ..     259     327 .. 0.87
   2 ?   14.4   0.3   5.2e-06     0.031      31     121 ..     334     421 ..     331     436 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.13
   ApoLp-III  26 tiKensenlvdqlkqvikslqeelkkksdeleealkevkkkieetadklseenPev 81 
                  +K+ns++  +q +q  ++ ++ l     e++++l++++++++ t + +  ++P++
  EEA20775.1 264 DVKDNSSTSNSQPSQSEAESTSLLSAFEAEMAKILENSQDAVNDTSNPIVPQEPQT 319
                 5899999999999999999999999999999*************999998888876 PP

  == domain 2  score: 14.4 bits;  conditional E-value: 5.2e-06
   ApoLp-III  31 senlvdqlkqvikslqeelkkksdeleealkevkkkiee.tadklseenPevkkkaqelqekvQsgvqslvkesqklaeslkensqeakekl 121
                 ++++++ + + i+++ +elk+ ++e+e+ l +++ +i e + +k++ + ++ + ++q+l + vQ++ +     s ++ae++ ++    +e++
  EEA20775.1 334 VTGVLQAVADGIENMGSELKTRIPEMERHLANAQRAIPEdVGAKMQTALSAFESQIQNLAQIVQQASN----ASGEAAERVRQADLRSTEQM 421
                 57889999999**************************7636799******************999754....35566666666655555555 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.1   4.8e-05      0.29      43     113 ..     331     399 ..     323     409 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 4.8e-05
     DUF1664  43 vesvskqleqvseslaatkrhLssridrvdkkldeqkeiskeikeev.tevredlseigedvesvkeavegl 113
                 v+ v+  l+ v + +++   +L+ ri +++++l +   ++++i e+v ++++  ls+++++++++ ++v++ 
  EEA20775.1 331 VNLVTGVLQAVADGIENMGSELKTRIPEMERHLAN---AQRAIPEDVgAKMQTALSAFESQIQNLAQIVQQA 399
                 6889999************************9965...4566777774478999999999999999999975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1099 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       880  (0.0490825); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.78u 0.29s 00:00:01.07 Elapsed: 00:00:00.45
# Mc/sec: 7346.12
//
Query:       EEA20776.1  [L=352]
Description: histone acetyltransferase (MysT1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.8e-62  207.9   0.0      2e-61  206.8   0.0    1.6  2  MOZ_SAS   MOZ/SAS family
    2.6e-17   62.2   0.7      5e-17   61.3   0.7    1.4  1  zf-MYST   MYST family zinc finger domain
  ------ inclusion threshold ------
       0.15   11.9   0.0       0.29   11.0   0.0    1.4  1  IF2_N     Translation initiation factor IF-2, N-terminal regi


Domain annotation for each model (and alignments):
>> MOZ_SAS  MOZ/SAS family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0       1.6   9.4e+03     122     145 ..      24      47 ..      24      51 .. 0.73
   2 !  206.8   0.0   3.3e-65     2e-61       1     177 [.      78     291 ..      78     293 .. 0.95

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 1.6
     MOZ_SAS 122 lgllsyrsywkeeilellkekekk 145
                 lg ls+r+++++   e l +k+++
  EEA20776.1  24 LGDLSFRTWYQSIYPEELVSKDTE 47 
                 578899999988888877776655 PP

  == domain 2  score: 206.8 bits;  conditional E-value: 3.3e-65
     MOZ_SAS   1 ppGkeiYrkeklsvfevdGekeklycqnLcllaklFldhktlyydvepFlfYvlteadeeg...ahivGyFskekesaeeynlaCilvlPpyqrkgyGk 96 
                 p G+++Y++  ++v+e+dGe++kl++qnL+l+aklFldhk++++dv++Fl+Yvlt +d ++   + ++GyFskek s++ +nlaCil++Ppyq+k++G+
  EEA20776.1  78 PLGEKVYEHGGYAVWEIDGEDDKLFAQNLSLFAKLFLDHKSVFFDVSSFLYYVLTFTDPNTpddYYVLGYFSKEKLSWDLNNLACILIFPPYQHKKLGR 176
                 679****************************************************99765433388********************************* PP

     MOZ_SAS  97 lliefsYeLskrekk...igtPekPlsdlgllsyrsywkeeilellkek...............................ekkkisieeisektgikee 161
                 ll+ +sY+Ls +e++   ig+Pe+Pls+lg+ sy+++w+e+++++l                                   +++++++ei ++tg+  e
  EEA20776.1 177 LLMGVSYKLSAWEWEgglIGGPERPLSELGHRSYTRFWEERMARYLLLGppggdpeeyiqqarqkkqaamkaaalrknspPRERMTVREIGQATGMLPE 275
                 ************9966669**************************99889***************************9998899*************** PP

     MOZ_SAS 162 Diistleelkllkyak 177
                 D+i++l+ + +++ ++
  EEA20776.1 276 DVITALKGMGVVEPEQ 291
                 ***********98776 PP

>> zf-MYST  MYST family zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.3   0.7   8.3e-21     5e-17       4      55 .]      19      72 ..      18      72 .. 0.94

  Alignments for each domain:
  == domain 1  score: 61.3 bits;  conditional E-value: 8.3e-21
     zf-MYST  4 iekieiGeyeiktWYfSpYPeel..ankekLyvCefClkYmksakelerHkkkC 55
                ++++ +G++ ++tWY+S+YPeel  +++e+LyvC +C++Y+++a ++  H k C
  EEA20776.1 19 VKRVVLGDLSFRTWYQSIYPEELvsKDTEELYVCRWCFRYTCDAAAYASHVKLC 72
                789********************7777789*********************999 PP

>> IF2_N  Translation initiation factor IF-2, N-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   4.8e-05      0.29       2      30 ..     259     286 ..     258     290 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 4.8e-05
       IF2_N   2 skirVyeLAkeLgvkskevikkLfkelGi 30 
                 + ++V+e+ +  g+ +++vi+ L k +G+
  EEA20776.1 259 ERMTVREIGQATGMLPEDVITAL-KGMGV 286
                 579********************.66998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (352 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       537  (0.0299515); expected 358.6 (0.02)
Passed bias filter:                      466  (0.0259914); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2449.44
//
Query:       EEA20777.1  [L=541]
Description: t-complex protein 1, zeta subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
   3.3e-164  547.2   0.9   3.7e-164  547.0   0.9    1.0  1  Cpn60_TCP1  TCP-1/cpn60 chaperonin family
  ------ inclusion threshold ------
       0.17   10.3   0.0       0.26    9.8   0.0    1.2  1  Herpes_UL6  Herpesvirus UL6 like


Domain annotation for each model (and alignments):
>> Cpn60_TCP1  TCP-1/cpn60 chaperonin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  547.0   0.9  4.1e-168  3.7e-164       1     490 [.      30     527 ..      30     528 .. 0.98

  Alignments for each domain:
  == domain 1  score: 547.0 bits;  conditional E-value: 4.1e-168
                 HHHHHHCCSSTTXXEEEEEETTSEEEEEXSHHHHHHCSXXXSHHHHHHHHHHHHCCCCCTTCHHHHHHHHHHHHHHHHHHHHCTXXHHHHHHHHHHHHH CS
  Cpn60_TCP1   1 ladivkttlGPkGmdKmlvnkggkvvvTnDGatilkeleiehPaakllveaaesqdeevGDGTttvviLageLleeaekliaagvhpttiiegyekale 99 
                 l+d++k++lGP G+ Kmlv+ +g +++T+DG+++l+e++i++P+a ++++aa++qd+ +GDGTt+vv+L+geLl++a + ia+g+hp+++++g+e a++
  EEA20777.1  30 LQDVLKSNLGPAGTIKMLVDGAGGIKLTKDGNVLLREMQIQNPTAVMIARAATAQDDITGDGTTSVVLLVGELLKQADRQIAEGLHPRVLTDGFELAKN 128
                 789************************************************************************************************ PP

                 HHHHHHHHHXEEBXSCSTT.HHHHHHHHHHCTTSSXXSTHHHHHHHHHHHHHCHCCCSEECSCCCEECCCCEECECTTSEEESEEEESS--SSTTSSCE CS
  Cpn60_TCP1 100 kaleaLkeiaveisseekdreeLlkvartslsskltskeaeelsklvvdAvklieenekeldlgrikvvkieggsledselveGlvldkgvlspdmpkk 198
                 ++l++L++   +i+ e  dre L++vartsls+kl ++ ae l+  vvdAv++i ++  + dl++i+++k++++s +d++l++Gl+ld+g ++pdmpk+
  EEA20777.1 129 ETLKFLDSF--KIDRE-IDRELLISVARTSLSTKLNNALAESLTPAVVDAVLAIYKAPAKPDLHMIEIMKMQHRSASDTQLIRGLALDHGARHPDMPKR 224
                 *********..77755.689*******************************9998888999************************************** PP

                 EECEEEEEESS-BS--HHCCHHHCCCCSCCHHHHHHHHHHHHHHHHHHHHHHTTECE..........EEESS-B-HHHHHHHHHCT-EEE-S--HHHHH CS
  Cpn60_TCP1 199 lenakvllldvsLeiektetkttvvlsdaeeleklekaeekqleellekiiksgvnv..........vvcqkgiddlalhflakngilalrrvkkkdle 287
                 +ena +l+l+vsLe+ek+e+++++ +s+ae+++kl+++e+++++ +l+ki++++++v          +++qkgid+l+l++l+kngi+alrr+k++++e
  EEA20777.1 225 VENAFILTLNVSLEYEKSEINSGFYYSSAEQRDKLVESERRFVDAKLQKIVELKKQVcgndpkkgfvIINQKGIDPLSLDVLVKNGIMALRRAKRRNME 323
                 *************************************************************************************************** PP

                 HHHHHHT--EBSCGGGGGCGC-EEEEEEEECCETTCCEEEEECESSSSXEEEEEEESTCCCHHHHHHHHHHHHHHHHHHHHHHEEEETTTCHHHHHHHH CS
  Cpn60_TCP1 288 rlakatGatavssledltpeelGtakkveeekigsekttiieevksgkiatillrgatdtvldeieraiedAlnvvknaiedekvvpGGGatelelakk 386
                 rl  ++G+ a +s++dltp+ lG+a+ v+e+++g+ek+t+ie+vk++k++t+l++g+++++++++ +a++d+l++v n+i d+ vvpG+G++ +++a++
  EEA20777.1 324 RLQLVCGGIAQNSVDDLTPDVLGWAGLVYEHQLGEEKYTFIEDVKDPKSVTLLIKGPNQHTIAQLTDAVRDGLRSVYNTIVDKSVVPGAGSFQVAAAAH 422
                 *************************************************************************************************** PP

                 H..HCCCCTSXCCHHHHHHHHHHHHTHHHHHHHHHCTSXHHHHHHHHHHHHHTTXTTEEEETTTTCEEECCCCTXEEEHHHHHHHHHHHHHHHHHHHCE CS
  Cpn60_TCP1 387 l..keyaksvsgeeqlaieafakALevipktLaeNaGldpievlaklraahnkgekelgidvesgeiidlveagvvDplkvkrqalksAteaastiLri 483
                 l  +e++k+v+g+ q++i+afa+AL+vipktLa N+G+d ++ lakl +++ +g+  +g+d+ sge+ d+v++gv+D+++v r+++ s+t +as +L +
  EEA20777.1 423 LlsEEFSKTVKGKAQYGIRAFADALLVIPKTLAANSGHDIQDSLAKLIDEQRQGH-VVGLDLSSGEAMDPVQEGVFDSYRVLRNCIASSTGIASNLLLC 520
                 *55589999**********************************************.******************************************* PP

                 EEEEXXX CS
  Cpn60_TCP1 484 deiikak 490
                 de +ka+
  EEA20777.1 521 DELLKAR 527
                 ***9987 PP

>> Herpes_UL6  Herpesvirus UL6 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0   2.9e-05      0.26     289     358 ..     367     428 ..     336     443 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 2.9e-05
  Herpes_UL6 289 ksdakkeLlklliklkenktvggitdvVedfleevsnslvdknklldasqpGfgkggasaqssekteqgl 358
                  +d+k   + llik  ++ t+  +td V+d l+ v n +vdk+       pG g+ +  a +++  ++++
  EEA20777.1 367 VKDPKS--VTLLIKGPNQHTIAQLTDAVRDGLRSVYNTIVDKSVV-----PGAGSFQV-AAAAHLLSEEF 428
                 578888..9********************************8877.....55555542.23333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (541 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       346  (0.0192983); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.32s 00:00:00.92 Elapsed: 00:00:00.50
# Mc/sec: 3250.25
//
Query:       EEA20778.1  [L=496]
Description: t-complex protein 1, zeta subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
   1.2e-156  522.2   0.7   1.4e-156  522.0   0.7    1.0  1  Cpn60_TCP1  TCP-1/cpn60 chaperonin family
  ------ inclusion threshold ------
       0.15   10.5   0.0       0.23   10.0   0.0    1.2  1  Herpes_UL6  Herpesvirus UL6 like


Domain annotation for each model (and alignments):
>> Cpn60_TCP1  TCP-1/cpn60 chaperonin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  522.0   0.7  1.5e-160  1.4e-156      17     490 ..       1     482 [.       1     483 [. 0.98

  Alignments for each domain:
  == domain 1  score: 522.0 bits;  conditional E-value: 1.5e-160
                 EEEETTSEEEEEXSHHHHHHCSXXXSHHHHHHHHHHHHCCCCCTTCHHHHHHHHHHHHHHHHHHHHCTXXHHHHHHHHHHHHHHHHHHHHHHXEEBXSC CS
  Cpn60_TCP1  17 mlvnkggkvvvTnDGatilkeleiehPaakllveaaesqdeevGDGTttvviLageLleeaekliaagvhpttiiegyekalekaleaLkeiaveisse 115
                 mlv+ +g +++T+DG+++l+e++i++P+a ++++aa++qd+ +GDGTt+vv+L+geLl++a + ia+g+hp+++++g+e a++++l++L++   +i+ e
  EEA20778.1   1 MLVDGAGGIKLTKDGNVLLREMQIQNPTAVMIARAATAQDDITGDGTTSVVLLVGELLKQADRQIAEGLHPRVLTDGFELAKNETLKFLDSF--KIDRE 97 
                 9*******************************************************************************************..77755 PP

                 STT.HHHHHHHHHHCTTSSXXSTHHHHHHHHHHHHHCHCCCSEECSCCCEECCCCEECECTTSEEESEEEESS--SSTTSSCEEECEEEEEESS-BS-- CS
  Cpn60_TCP1 116 ekdreeLlkvartslsskltskeaeelsklvvdAvklieenekeldlgrikvvkieggsledselveGlvldkgvlspdmpkklenakvllldvsLeie 214
                   dre L++vartsls+kl ++ ae l+  vvdAv++i ++  + dl++i+++k++++s +d++l++Gl+ld+g ++pdmpk++ena +l+l+vsLe+e
  EEA20778.1  98 -IDRELLISVARTSLSTKLNNALAESLTPAVVDAVLAIYKAPAKPDLHMIEIMKMQHRSASDTQLIRGLALDHGARHPDMPKRVENAFILTLNVSLEYE 195
                 .689*******************************9998888999****************************************************** PP

                 HHCCHHHCCCCSCCHHHHHHHHHHHHHHHHHHHHHHTTECE..........EEESS-B-HHHHHHHHHCT-EEE-S--HHHHHHHHHHHT--EBSCGGG CS
  Cpn60_TCP1 215 ktetkttvvlsdaeeleklekaeekqleellekiiksgvnv..........vvcqkgiddlalhflakngilalrrvkkkdlerlakatGatavssled 303
                 k+e+++++ +s+ae+++kl+++e+++++ +l+ki++++++v          +++qkgid+l+l++l+kngi+alrr+k++++erl  ++G+ a +s++d
  EEA20778.1 196 KSEINSGFYYSSAEQRDKLVESERRFVDAKLQKIVELKKQVcgndpkkgfvIINQKGIDPLSLDVLVKNGIMALRRAKRRNMERLQLVCGGIAQNSVDD 294
                 *************************************************************************************************** PP

                 GGCGC-EEEEEEEECCETTCCEEEEECESSSSXEEEEEEESTCCCHHHHHHHHHHHHHHHHHHHHHHEEEETTTCHHHHHHHHH..HCCCCTSXCCHHH CS
  Cpn60_TCP1 304 ltpeelGtakkveeekigsekttiieevksgkiatillrgatdtvldeieraiedAlnvvknaiedekvvpGGGatelelakkl..keyaksvsgeeql 400
                 ltp+ lG+a+ v+e+++g+ek+t+ie+vk++k++t+l++g+++++++++ +a++d+l++v n+i d+ vvpG+G++ +++a++l  +e++k+v+g+ q+
  EEA20778.1 295 LTPDVLGWAGLVYEHQLGEEKYTFIEDVKDPKSVTLLIKGPNQHTIAQLTDAVRDGLRSVYNTIVDKSVVPGAGSFQVAAAAHLlsEEFSKTVKGKAQY 393
                 ************************************************************************************55589999******* PP

                 HHHHHHHHHTHHHHHHHHHCTSXHHHHHHHHHHHHHTTXTTEEEETTTTCEEECCCCTXEEEHHHHHHHHHHHHHHHHHHHCEEEEEXXX CS
  Cpn60_TCP1 401 aieafakALevipktLaeNaGldpievlaklraahnkgekelgidvesgeiidlveagvvDplkvkrqalksAteaastiLrideiikak 490
                 +i+afa+AL+vipktLa N+G+d ++ lakl +++ +g+  +g+d+ sge+ d+v++gv+D+++v r+++ s+t +as +L +de +ka+
  EEA20778.1 394 GIRAFADALLVIPKTLAANSGHDIQDSLAKLIDEQRQGH-VVGLDLSSGEAMDPVQEGVFDSYRVLRNCIASSTGIASNLLLCDELLKAR 482
                 ***************************************.**********************************************9987 PP

>> Herpes_UL6  Herpesvirus UL6 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   2.5e-05      0.23     289     358 ..     322     383 ..     291     399 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 2.5e-05
  Herpes_UL6 289 ksdakkeLlklliklkenktvggitdvVedfleevsnslvdknklldasqpGfgkggasaqssekteqgl 358
                  +d+k   + llik  ++ t+  +td V+d l+ v n +vdk+       pG g+ +  a +++  ++++
  EEA20778.1 322 VKDPKS--VTLLIKGPNQHTIAQLTDAVRDGLRSVYNTIVDKSVV-----PGAGSFQV-AAAAHLLSEEF 383
                 578888..9********************************8877.....55555542.23333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (496 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       483  (0.0269396); expected 358.6 (0.02)
Passed bias filter:                      439  (0.0244855); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.26s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3359.89
//
Query:       EEA20779.1  [L=507]
Description: pre-rRNA processing nucleolar protein Sik1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.5e-88  296.1   0.0    1.5e-88  296.1   0.0    1.5  2  Nop             snoRNA binding domain, fibrillarin
    1.4e-19   70.2   0.2    1.4e-19   70.2   0.2    2.2  2  NOP5NT          NOP5NT (NUC127) domain
  ------ inclusion threshold ------
      0.042   13.9  34.4      0.067   13.3  34.4    1.3  1  RNA_polI_A34    DNA-directed RNA polymerase I subunit RPA34.5
       0.44   10.6  24.1       0.63   10.1  24.1    1.2  1  YL1             YL1 nuclear protein
        2.5    8.3  12.5        5.5    7.2  12.5    1.6  1  GAGA_bind       GAGA binding protein-like family
        4.9    6.9   7.2        9.3    5.9   7.2    1.4  1  EIIBC-GUT_N     Sorbitol phosphotransferase enzyme II N-termi
        8.8    5.6  22.7        1.1    8.6  17.9    2.0  3  CobT            Cobalamin biosynthesis protein CobT
        9.9    6.2   8.5         48    3.9   0.0    2.3  2  RP-C_C          Replication protein C C-terminal region


Domain annotation for each model (and alignments):
>> Nop  snoRNA binding domain, fibrillarin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  296.1   0.0   6.7e-92   1.5e-88       2     229 ..     181     413 ..     180     414 .. 0.94
   2 ?   -6.1   2.6         8   1.8e+04      67      67 ..     478     478 ..     454     497 .. 0.48

  Alignments for each domain:
  == domain 1  score: 296.1 bits;  conditional E-value: 6.7e-92
                 HHHHHHHHHHHHHHHHHHHTTTSTCHHHHS-SHHHHHHHHHHCCCCHCCT.HH..TT........HH.HHHHHHHHHHCHHHH-SSS-S-HHHHHHHHH CS
         Nop   2 ldeidkeintlhkrvrewYswhFpELeslvkdnleYakvvkligneredlekk..ee.......dee.lakevimaakvtastsmgaelseedlknike 90 
                 ld++dk int+++rvrewYswhFpEL ++v++n+ Ya+v+ +++ ++++l+++  ++       d e +a+++i+aak+    smg+++se+d++n+ +
  EEA20779.1 181 LDQLDKAINTFSMRVREWYSWHFPELIKIVSENYRYAHVALFVQ-DKKSLTDDrlHDlaalvedD-EgVARTIIEAAKH----SMGQDISETDMENVIS 273
                 89******************************************.77777555343378888734.4599999999999....**************** PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHCHHHHHHHHHHHHSSHHHHHCS-HHHHTTTT-HHHHCCCHH.T---SSSCHHHCSHHHHHTS-CCC CS
         Nop  91 lcdrvleleelrkelleYlesrmsaiAPNlsaLvGeevaarLishaGgLtnLakmPastiqilGaekalfralk.kkntpkyGliyhselvqkatppkl 188
                 +++rv++l+++rk+l++Yl s+ms++APNl+aL+Ge v+arLishaG+LtnL+k+Past+qilGaekalfralk k+ntpkyGl+yhs+++++a  pk+
  EEA20779.1 274 FAKRVVSLSDYRKSLHSYLVSKMSVVAPNLAALIGEVVGARLISHAGSLTNLSKYPASTVQILGAEKALFRALKtKGNTPKYGLLYHSSFIGRA-GPKN 371
                 **************************************************************************777***************88.**** PP

                 HHHHHHHHHHHHHHHHHHHHTT---.-SHHHHHHHHHHHHHH CS
         Nop 189 kkkiaRllaaKvalaaRiDafsekd.gslGkklreeiekklk 229
                 k++i+R+la+K+++a+RiD+fse++ +++G++l++++e++l+
  EEA20779.1 372 KGRISRFLANKCSIASRIDNFSETPsTKFGEALKKQVEERLE 413
                 *********************99999**************97 PP

  == domain 2  score: -6.1 bits;  conditional E-value: 8
                 H CS
         Nop  67 a 67 
                  
  EEA20779.1 478 K 478
                 1 PP

>> NOP5NT  NOP5NT (NUC127) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.2   0.2   6.2e-23   1.4e-19       1      65 []       4      70 ..       4      70 .. 0.95
   2 ?   -7.5   4.9         8   1.8e+04      23      23 ..     476     476 ..     458     493 .. 0.49

  Alignments for each domain:
  == domain 1  score: 70.2 bits;  conditional E-value: 6.2e-23
      NOP5NT  1 fiLfEtaaGYaLfkv.kdk....kllkkddlvkdsvsdlekfsklvkLkaFqkFesaaeALenanaiseG 65
                +iLfE ++GY+Lfk  +++    + lk+   v++sv dl+kf+k+v+L++F +Fe++++AL+++n+iseG
  EEA20779.1  4 YILFEAPMGYSLFKTvHQAdtvgNSLKE---VQESVLDLAKFGKMVELVSFLPFENNKQALSEINDISEG 70
                9*************95555999999999...**************************************9 PP

  == domain 2  score: -7.5 bits;  conditional E-value: 8
      NOP5NT  23 k 23 
                 k
  EEA20779.1 476 K 476
                 1 PP

>> RNA_polI_A34  DNA-directed RNA polymerase I subunit RPA34.5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3  34.4     3e-05     0.067     127     204 ..     433     506 ..     411     507 .] 0.72

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 3e-05
                   XX............XXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXX..XXXXXX...XXXXXXXX CS
  RNA_polI_A34 127 gtigssseesegekekkkkpkakkkekkkkkkkaaeedeeeeapkkkkkkkkkkkekkeeekkeekeeeskkskkkKK 204
                    +i  + + +e e++++++++++k++k+kk+k+a++++   +++kk+kk+kk+kk k+e+++k ++e    +skkk K
    EEA20779.1 433 DSILADMDVDEPEDSDVEMDDEEKPKKAKKEKEAKDKE--GKKEKKEKKEKKEKKNKEEKKRKRDSE--VGSSKKKSK 506
                   5555666778999999999***********99999999..888888888888888888744444444..444444433 PP

>> YL1  YL1 nuclear protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1  24.1   0.00028      0.63      45     109 ..     443     504 ..     401     507 .] 0.54

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00028
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         YL1  45 eeensDsdfdsdeedeesdeeedeeegekelerqerkkrkkekkkrkaqkkkskkkkkkqkkkkk 109
                 e   +Dsd++ d+e++++++++++e+++ke ++++++k++k++kk+k++kk ++ ++   ++kkk
  EEA20779.1 443 E--PEDSDVEMDDEEKPKKAKKEKEAKDKEGKKEKKEKKEKKEKKNKEEKKRKRDSE-VGSSKKK 504
                 1..245555555555555555555555555555555555333333332222222222.2222222 PP

>> GAGA_bind  GAGA binding protein-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2  12.5    0.0024       5.5     112     176 ..     437     500 ..     377     507 .] 0.58

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0024
   GAGA_bind 112 qeaeapelekeevasselveesavvekeeaakkrqqgkrpkepkakkakkaarkpkeegedlalk 176
                  + + +e e+++v+  +  e+ + ++ke++ak ++ +k++ke+k kk kk++++ k+++++ + +
  EEA20779.1 437 ADMDVDEPEDSDVE-MDDEEKPKKAKKEKEAKDKEGKKEKKEKKEKKEKKNKEEKKRKRDSEVGS 500
                 33333333333333.22333333344456666666666666666666666555555554433222 PP

>> EIIBC-GUT_N  Sorbitol phosphotransferase enzyme II N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   7.2    0.0042       9.3     107     157 ..     441     491 ..     414     502 .. 0.63

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0042
  EIIBC-GUT_N 107 vSgvkeeqieladeeeeeeeeeeeekeeaeekekkketkkkiteqeekekk 157
                  v + + +++e+ dee+ +++++e+e++++e k++kke+k+k+++++++ekk
   EEA20779.1 441 VDEPEDSDVEMDDEEKPKKAKKEKEAKDKEGKKEKKEKKEKKEKKNKEEKK 491
                  555566677777666666666655555555555444444444444444433 PP

>> CobT  Cobalamin biosynthesis protein CobT
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       2.1   4.8e+03     172     194 ..      24      46 ..      22      49 .. 0.87
   2 ?   -2.7   0.1       1.4   3.1e+03     174     194 ..     231     251 ..     226     262 .. 0.84
   3 ?    8.6  17.9    0.0005       1.1     184     263 ..     422     500 ..     401     507 .] 0.51

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 2.1
        CobT 172 kagkdldrlaealeDqkaFarav 194
                  +g++l++++e++ D ++F+++v
  EEA20779.1  24 TVGNSLKEVQESVLDLAKFGKMV 46 
                 68999**************9987 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 1.4
        CobT 174 gkdldrlaealeDqkaFarav 194
                 +++l +la+ +eD + +ar++
  EEA20779.1 231 DDRLHDLAALVEDDEGVARTI 251
                 568999999999999999987 PP

  == domain 3  score: 8.6 bits;  conditional E-value: 0.0005
        CobT 184 leDqkaFaravrqlLqdldlaeesaeepeeedeeeeedeeeeeeeseeeeeegedddkeeqeeaaseeeeeededeeske 263
                 ++++ a  +a+ ++L+d+d   e ++++ e d+ee+ +++++e+e++++e+++e+++k+e++e++++ee++ ++d+e ++
  EEA20779.1 422 TKNEIAMKSAMDSILADMDVD-EPEDSDVEMDDEEKPKKAKKEKEAKDKEGKKEKKEKKEKKEKKNKEEKKRKRDSEVGS 500
                 5667788899999******66.3333333333333333333333333334444444444444444444444433333222 PP

>> RP-C_C  Replication protein C C-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.022        48     117     157 ..     222     262 ..     217     288 .. 0.86
   2 ?    0.9   7.5      0.19   4.2e+02      49      89 ..     454     488 ..     397     506 .. 0.42

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.022
      RP-C_C 117 YapdgairsWrdLvaaAevvrsmlgvspsaweeAcevmGre 157
                 +++d+++ +   L++ A+ v    gv + + e A++ mG++
  EEA20779.1 222 FVQDKKSLTDDRLHDLAALVEDDEGVARTIIEAAKHSMGQD 262
                 6666666777789**************************97 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.19
      RP-C_C  49 aenssanesqnerhiqnsnpdsssesepasekereekeaaa 89 
                 +e+ ++ ++++e++ +++++++++++e      ++ek++++
  EEA20779.1 454 EEKPKKAKKEKEAKDKEGKKEKKEKKE------KKEKKNKE 488
                 111122222222222222222211111......11111111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (507 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2672  (0.149032); expected 358.6 (0.02)
Passed bias filter:                      914  (0.0509789); expected 358.6 (0.02)
Passed Vit filter:                       249  (0.0138881); expected 17.9 (0.001)
Passed Fwd filter:                        29  (0.00161749); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.87u 0.35s 00:00:01.22 Elapsed: 00:00:00.48
# Mc/sec: 3155.70
//
Query:       EEA20780.1  [L=272]
Description: hypothetical protein PMAA_046020 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
  ------ inclusion threshold ------
        7.5    7.3   8.2         20    5.9   7.7    2.1  1  U1snRNP70_N  U1 small nuclear ribonucleoprotein of 70kDa MW N


Domain annotation for each model (and alignments):
>> U1snRNP70_N  U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   7.7    0.0011        20      50      90 ..     219     259 ..     138     261 .. 0.70

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0011
  U1snRNP70_N  50 eeeqeppektetkeekkererkekkekkeekleealeeydP 90 
                  ++ q+ ++++  ++++++re++ek++++ e + + ++eydP
   EEA20780.1 219 ARSQQRQKQVTEWKNREAREAREKRRERREGVSRVKSEYDP 259
                  34556666688899**************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (272 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1055  (0.0588432); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.50
# Mc/sec: 1645.24
//
Query:       EEA20781.1  [L=192]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-36  124.5   0.0    1.8e-36  124.0   0.0    1.2  1  DUF3767       Protein of unknown function (DUF3767)
  ------ inclusion threshold ------
       0.13   11.8   0.8       0.17   11.4   0.8    1.1  1  5TM-5TMR_LYT  5TMR of 5TMR-LYT
        3.5    7.4   5.9         13    5.5   0.1    2.2  2  DUF4718       Domain of unknown function (DUF4718)
        5.6    6.3  10.9        3.8    6.8   0.1    2.1  2  Nop53         Nop53 (60S ribosomal biogenesis)


Domain annotation for each model (and alignments):
>> DUF3767  Protein of unknown function (DUF3767)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  124.0   0.0     4e-40   1.8e-36       2     100 ..      62     162 ..      61     163 .. 0.97

  Alignments for each domain:
  == domain 1  score: 124.0 bits;  conditional E-value: 4e-40
     DUF3767   2 aslsdavktisledfsklvsiPCaRdslltGigagavvGglrfvlkk..nvakaaNWavgafllgsivayeqCrarrrkekekmkravevvkekkakke 98 
                 +++s+++k+i+ledfs++++ PCaRdsll+G+gag+++Gg+r ++++   ++ a+NWavgaf+++s+++ye+C++rr +e+++m++ave+++e kakk+
  EEA20781.1  62 ITISESLKSIKLEDFSTFHKKPCARDSLLVGLGAGFGIGGIRGIVGGlsAMWPASNWAVGAFAIASLASYEFCQRRRVNEMKGMQKAVELMAELKAKKQ 160
                 6899******************************************9999************************************************9 PP

     DUF3767  99 ke 100
                 +e
  EEA20781.1 161 RE 162
                 98 PP

>> 5TM-5TMR_LYT  5TMR of 5TMR-LYT
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.8   3.8e-05      0.17      61     108 ..      90     140 ..      88     154 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 3.8e-05
  5TM-5TMR_LYT  61 lvGliagliaglhRyllgGftal.acgistilagllaGlihrklkrrr..k 108
                   lvGl+ag+ +g  R ++gG +a+ +++  ++ a ++a+l+++ + +rr  +
    EEA20781.1  90 LVGLGAGFGIGGIRGIVGGLSAMwPASNWAVGAFAIASLASYEFCQRRrvN 140
                   89*****************66651677889999999999999988875342 PP

>> DUF4718  Domain of unknown function (DUF4718)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.1    0.0029        13      16      43 ..     117     144 ..     110     155 .. 0.81
   2 ?    3.5   2.1     0.012        54      83     107 ..     157     181 ..     149     188 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0029
     DUF4718  16 slGiGffalasalwflickrreifeesk 43 
                    +G fa+as   +  c+rr + e   
  EEA20781.1 117 NWAVGAFAIASLASYEFCQRRRVNEMKG 144
                 5679*****************9987654 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.012
     DUF4718  83 ekrkkeeaeikaikdhskeefclad 107
                  k+++e++++kai+d   ee   ++
  EEA20781.1 157 AKKQREKEQLKAIQDAEAEELRKQK 181
                 6899***********9999987665 PP

>> Nop53  Nop53 (60S ribosomal biogenesis)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.1   0.00085       3.8     181     193 ..      42      54 ..       3      56 .. 0.65
   2 ?    2.0   6.3     0.024   1.1e+02     276     310 ..     147     181 ..     133     186 .. 0.51

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.00085
       Nop53 181 vevphaGkSYNPs 193
                    +h+G+SYNP+
  EEA20781.1  42 RINVHPGASYNPA 54 
                 4568********7 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.024
       Nop53 276 apvkkkpkrKTkaqRnkekrrkeeekeekeekkek 310
                 + v+ +++ K k+qR+ke+ +  + +e++e++k+k
  EEA20781.1 147 KAVELMAELKAKKQREKEQLKAIQDAEAEELRKQK 181
                 23333344555555555555555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (192 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1652  (0.0921412); expected 358.6 (0.02)
Passed bias filter:                      821  (0.0457917); expected 358.6 (0.02)
Passed Vit filter:                        69  (0.00384851); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 1352.78
//
Query:       EEA20782.1  [L=2224]
Description: DNA polymerase epsilon, catalytic subunit A/POL2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.6e-150  501.2   0.0   2.2e-150  500.7   0.0    1.2  1  DUF1744         Domain of unknown function (DUF1744)
    6.3e-83  278.7   0.2    7.3e-82  275.2   0.1    2.3  2  DNA_pol_B_exo1  DNA polymerase family B, exonuclease domain
    1.6e-14   53.5   0.0    1.4e-11   43.8   0.0    3.4  3  DNA_pol_B       DNA polymerase family B
      1e-08   35.2   0.1    2.5e-08   33.9   0.1    1.6  1  DNA_pol_B_exo2  Predicted 3'-5' exonuclease related to the ex
    4.5e-05   23.5   0.0    0.00021   21.3   0.0    2.2  1  RNase_H_2       RNase_H superfamily


Domain annotation for each model (and alignments):
>> DUF1744  Domain of unknown function (DUF1744)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  500.7   0.0  6.3e-154  2.2e-150       2     400 ..    1520    1903 ..    1519    1904 .. 0.96

  Alignments for each domain:
  == domain 1  score: 500.7 bits;  conditional E-value: 6.3e-154
     DUF1744    2 eklykeelek.keekeekkeelieypeklkfeveyvkdekkalkalsralkklkeeksgptllvlqspkelkkleskipalsefPvvklpsnkaess 97  
                  +k+y e+l +   +++e+++ +++y+ek++f++++v++ +ka+ ++ + +kkl++e+s+p+++v+qs+++ +kl ++ip+l+++P+++++ + ++++
  EEA20782.1 1520 DKMYVELLGRkIAAESEASTGAFDYQEKVHFKTTQVTTLRKAILEVGDLVKKLRNEESQPVVFVIQSQQK-RKLCHDIPILKDYPMLSVKPEVSDTD 1615
                  789999988855667777899************************************************9.************************** PP

     DUF1744   98 lpalgWqsvvakrlvehylklgswlaelielaryadvPlgnlesddllfliDiffaRrLkksnvvLWwsesprPDlGGlekDdklealslleelesp 194 
                  +p+lgWqs++akrl++hyl lgsw+++l  lary+dvP++nlesdd+++liD+++aRrL+ksnvvLWws++prPD++G+ekDd   +l +l+++e+p
  EEA20782.1 1616 MPPLGWQSFIAKRLLTHYLYLGSWIQHLKMLARYGDVPVCNLESDDPRYLIDVSYARRLEKSNVVLWWSAGPRPDHAGYEKDD---ILGSLDTVEMP 1709
                  **********************************************************************************9...8889******* PP

     DUF1744  195 einnpgaYssvcveleirnLavntilqsalinelEgssssvafddasseeldeyekgeaessssldesalssaafrvLrslvkswlddalkgnklad 291 
                  ++n pg+Y++v++ele+rnLa+ntil+s++in+lEgs++           l +++ +e+   + ++e+a++sa + vLr++vk+w+++a+ gn++ad
  EEA20782.1 1710 SVNVPGTYTTVSIELEVRNLAINTILTSSIINDLEGSDT-----------LLAST-KESADGVLYSEKAFASAGVFVLREMVKQWWSEACTGNTMAD 1794
                  ************************************975...........33333.3456789********************************** PP

     DUF1744  292 llvqhlvrWvespsslLyDpaLrrlvqnlmkKvflqLlaefkrlgskvvyAdfnkillkTsKksvenayaYveyilkairskelFkflelkikkyWd 388 
                  ++vqhlvrWvespss+LyD++L+++v+++++K+f+qL+ +f+r+gs+v++A+++++ll+T+K++v++ayaY++yilk+ir++++F+f++l+ k+yWd
  EEA20782.1 1795 IMVQHLVRWVESPSSCLYDRSLHYYVRMMSRKSFQQLMGDFRRVGSNVIFASPTRLLLQTTKQEVGTAYAYSQYILKSIRANPIFHFIDLELKEYWD 1891
                  ************************************************************************************************* PP

     DUF1744  389 lLlwmDeaNygG 400 
                  +L+w+De+NygG
  EEA20782.1 1892 FLVWYDEFNYGG 1903
                  ************ PP

>> DNA_pol_B_exo1  DNA polymerase family B, exonuclease domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  275.2   0.1     2e-85   7.3e-82       2     337 .]      99     438 ..      98     438 .. 0.99
   2 ?    0.8   0.0     0.059   2.1e+02      48     118 ..    1276    1347 ..    1256    1386 .. 0.71

  Alignments for each domain:
  == domain 1  score: 275.2 bits;  conditional E-value: 2e-85
                     ECTTSEEEEEEEE---EEEEEESSCGGHHHHHHHHHHHCCTTCCCEEEEEEEECCCCEECCTSSCCHHCEEEEEESSTCHHHHHHHHHHH..... CS
  DNA_pol_B_exo1   2 teegksvcvnvfgfkpyfYceapdgkeleevkeelkelyeelskkvtkivkvelvlkkslygyekkpvpylkvsvsnpnelkkirkelsp..... 91 
                      ++++ +++ +++++pyf+++++ g+e+ ev+e+++++ e+  k+v+++v+++l+++++l+g+ ++   +l++s++n+ +l+++rk l+p     
      EEA20782.1  99 LDDDGNNFKATVEYDPYFLIAVKGGREQ-EVEEWCRRILEGVVKDVRRVVREDLQMPNHLLGNRRT---FLRLSFANVGNLLEARKLLMPiaekn 189
                     589999*****************88887.*************************************...************************** PP

                     ......................................CCCCCCCCSSS--HHHHHHHHCTS-TTCEEEEETEEEEGCC--C-.SEEEEEETTTS CS
  DNA_pol_B_exo1  92 ......................................leeivdvyeydvdylerflidnkivgfgwysvkkylvraegkisncdveidcdvddl 148
                                                           ++ i+d++eydv+y++r++id++i+ ++wy+v+         +++  ++++c  ++l
      EEA20782.1 190 kknvtamdtyaemartsagfdlfddeldgsrpnatlnaSDFIIDIREYDVPYHVRVSIDKDIRIGKWYNVE---------AKHGVTKLTCIEERL 275
                     **************************************999******************************.........*************** PP

                     CEETTTCCS-EEEEEEEEEETEETTSEETTTT..--EEEEEEEECCTC.SS.SEEEEEEECCCTSS----EE--SSTCSTTE.EEEEESSHHHHH CS
  DNA_pol_B_exo1 149 iakpkesepplrvlsFDIeckskkgkfpdaensedpiiqIscvldglgekepearklftlrecaseeeedfeltpkpeypgv.kvlefdsEkelL 242
                     ++      ++++vl+FDIe++++++kfpda +  d+i++Is+++dg g       +l+t+re++se+++dfe+tpkpey+g+  ++++++E+++L
      EEA20782.1 276 QR------ADPVVLAFDIETTKLPLKFPDAVI--DQIMMISYMIDGNG-------FLITNREIVSEDINDFEYTPKPEYSGPfVIFNEPDERHVL 355
                     **......************************..**************.......**************************************** PP

                     HHHHHHHHHH--SEEEESSTTTTHHHHHHHHHHHCCTCCHCG.SCCSCTCEECCCCESEEEEEECEEEETTSEEEEHHHHHHHHSSSS..G-SHH CS
  DNA_pol_B_exo1 243 qaflefikqydPdvitgYNidnFDlpYilnRakelykvklsklgrlnkggrskvseigfskqarekvkisgrihlDlyrvvkrklklp..sYkLn 335
                     ++f+++ik+ +P+vi +YN+d+FD+p++++Ra+                g+ +  eigf+k++++++++++  h+D++++v+r+++lp  s  L+
      EEA20782.1 356 ERFFSHIKEAKPTVIATYNGDFFDWPFVEARAS--------------VLGIDMYAEIGFKKNSEDIYQSDHSAHMDCFAWVNRDSYLPqgSRGLK 436
                     *********************************..............9**********************************************9 PP

                     HH CS
  DNA_pol_B_exo1 336 av 337
                     av
      EEA20782.1 437 AV 438
                     98 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.059
                      E....EEEEEECCCCEECCTSSCCHHCEEEEEESSTCHHHHHHHHHHHCCCCCCCCSSS--HHHH..HHHHCTS-TT CS
  DNA_pol_B_exo1   48 t....kivkvelvlkkslygyekkpvpylkvsvsnpnelkkirkelspleeivdvyeydvdyler..flidnkivgf 118 
                      +    ki k   + +++l+g + k+++ l  +++n+ +++ i+++      + + +e+dv+  +r  +lid++++  
      EEA20782.1 1276 QkqkwKIQKQARIRRRQLFGEKSKASDSLSHYFRNQAQILFINTWT-----VLQLRETDVPGEVRafVLIDRRVHAL 1347
                      2356677788888899********999****************998.....59********9998444677776654 PP

>> DNA_pol_B  DNA polymerase family B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0      0.67   2.4e+03       6      49 ..     503     554 ..     501     567 .. 0.65
   2 !    3.2   0.0    0.0081        29      61      89 ..     632     660 ..     628     711 .. 0.88
   3 !   43.8   0.0   3.8e-15   1.4e-11     147     456 ..     807    1153 ..     790    1155 .. 0.70

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 0.67
                 HHHS-HHHHHHHHHHHHHHHTTBE-B-----.--SS............-S----B CS
   DNA_pol_B   6 vledgqqirveslLlrlakeegfilpdrtekkgkeee...........gYqGatV 49 
                 vl +g  +  e+lL+ +a + ++ilp+++++     e           +Y G+ V
  EEA20782.1 503 VLRKGTGTLCEMLLMVQAYKGEIILPNKHKDP---PEsfyeghlldseTYVGGHV 554
                 678889999999**************643332...22223444444434666666 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.0081
                 EEEEEETTHHHHHHHHTT-STTTCE-HCC CS
   DNA_pol_B  61 vlvlDFaSLYPsiiqahNlcyttlvasee 89 
                 +  lD aS+YP+i+  + l +  + ++ +
  EEA20782.1 632 IYHLDVASMYPNIMTTNRLQPDSMKQESD 660
                 6679***********99999988877765 PP

  == domain 3  score: 43.8 bits;  conditional E-value: 3.8e-15
                  HHHHHHHHHHHHHHHHHHHHHHHHTSTTSTT--HHHHHHHHHHHHHHHHHHHHHHHHT......SSG.........GGT-SS..........T-EEE CS
   DNA_pol_B  147 fekalldkqQlalKvtaNsvYGftGvansrlpclalAasvTtiGRemLektkelvekk...aellsk.........llalpeea....eee.klkvi 226 
                  ++ +l+d+ Qla Kv+ Ns+YG++  + sr +++++A     +G +++++++elve+        +           + +pe++    ++  k+   
  EEA20782.1  807 KMIVLFDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGVTCLTGARIIQMARELVERIgrpL---ELdtdgiwcmlPATFPENFaftlKNGkKMALS 900 
                  346789**************************************************884322...22223554433334444333333233466666 PP

                  EEBSSEEEEE-...S-SSHHHHHHHHHHHHHHHHT.TSTTT--EEEEEEEEEEEEEE........TTEEEEEEEEESSTTSEEEEESSGGGSTTS-H CS
   DNA_pol_B  227 YGDTDSvfiel...kvkdveellkigkelaeevseklfkkplklefekvykkllLis........KKkYaglkvektskanklliKGvdlvRrdnck 312 
                  Y     v+++    +  + ++  ++ +    + ++ +  + +  e++  yk ++L +        KK+Ya +  +     +  + KG ++ Rr+  k
  EEA20782.1  901 YP---CVMLNHlvhGRFTNHQYQTLIDPKSFKYET-TSDNSIFFEVDGPYKAMILPAskeedknlKKRYAVFNDD----GSLAELKGFEVKRRGELK 989 
                  63...566665554235555555555544444444.45778**************65444455558999877766....33479************* PP

                  HHHHHHHHHHHHHSSS....S-HHHHHHHHHHHHHHHH...HHHHTT-S-GGGG-EEEEESS.CCCSSGCCSHHHHHHHHHHHHCSS---TTCE... CS
   DNA_pol_B  313 lvkevikkvlelllkdeteersleeglealksilkdvl...eeleenkvplekfvlskelskepenyksknlphlevakrlkkrneeapevgdr... 403 
                  l+k   +++ +  l  e  ++  +++ +  ++ l+ ++   + l++++  ++  + ++++sk+ e+y +++   ++ akrl++  +e+  ++dr   
  EEA20782.1  990 LIKIFQTQIFKFFLDGEDLAETYQSVARVANRWLDVLYehgATLADEE-LIDLICENRSMSKTVEEYGAQKSTSITTAKRLAEFLGEQ-MIKDRgln 1084
                  ***************977555555555555555544442103343333.4666677899********999989********9998444.24444333 PP

                  EEEEEBETSS......................SS-GGGTEEEHHHHHHCCSEB-HHHHHHTTHHHHHHHH CS
   DNA_pol_B  404 isYvivekkkev.................kkknllaseraedpeyvleknlpidieyYlsqllkevarll 456 
                    Y+i +k k++                 +k+  l++ ++ dp+   + +  id +yYl++l + + +l+
  EEA20782.1 1085 CRYIISSKPKNApvteraipvtifsaeenIKRFFLRKWLKDDPS-DMDPRSIIDWDYYLERLGSVIQKLI 1153
                  89***999987799999999999987764333344444444444.44566679999**999999998887 PP

>> DNA_pol_B_exo2  Predicted 3'-5' exonuclease related to the exonuclease domain of PolB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.9   0.1     7e-12   2.5e-08      35     174 ..     349     485 ..     344     487 .. 0.80

  Alignments for each domain:
  == domain 1  score: 33.9 bits;  conditional E-value: 7e-12
  DNA_pol_B_exo2  35 ssekelikkffegvekkkpqlV.sfngrgfDlpvleyralkhgvsapkyfdegdedrekkwnnylsrystrhlDLmdlls..eygaranakLde. 125
                      +e++++++ff++++++kp+++ ++ng  fD p +e ra + g+    y++ g    +k+ ++  +  ++ h+D    +   +y ++ +  L+  
      EEA20782.1 349 PDERHVLERFFSHIKEAKPTVIaTYNGDFFDWPFVEARASVLGID--MYAEIGF---KKNSEDIYQSDHSAHMDCFAWVNrdSYLPQGSRGLKAv 438
                     5799***************98758***************998875..6889998...44556666777888999999886335877777777651 PP

  DNA_pol_B_exo2 126 .lakllglPGKlgvdGskVaelyqegklkeireYcetDvlnTYlvylrle 174
                      +akl   P  l+    + ++ y++++ ++++eY  +D++ TY +y+++ 
      EEA20782.1 439 tVAKLGYDPDELD---PELMTRYASERPQTLAEYSVSDAVATYYLYMKYI 485
                     1455555565555...57899**************************986 PP

>> RNase_H_2  RNase_H superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.0   5.9e-08   0.00021      39     162 ..     347     481 ..     338     484 .. 0.71

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 5.9e-08
   RNase_H_2  39 eepeeekailelflellekk.kalvtfngksFDvpflkrlf....kkyklde................eefrhiDLlkelrkkkl....esysLksvek 112
                 +ep+e++ ++++f ++ e k + + t+ng  FD+pf++ ++         d                 ++  h+D + ++++  +    ++ +Lk+v  
  EEA20782.1 347 NEPDERHVLERFFSHIKEAKpTVIATYNGDFFDWPFVEARAsvlgI----DMyaeigfkknsediyqsDHSAHMDCFAWVNRDSYlpqgSR-GLKAVTV 440
                 5788888889988776666636689****************66662....3333446666888888777779********99999999655.9999987 PP

   RNase_H_2 113 e.lgierreedlsGsqavklyqeylrtgdeellekilaYNedDvralatly 162
                 + lg++ +e        ++l ++y     +e  +++++Y   D +a+++ly
  EEA20782.1 441 AkLGYDPDE------LDPELMTRYA----SERPQTLAEYSVSDAVATYYLY 481
                 668988873......3355555664....3333455666666666666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2224 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       613  (0.0341904); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 1.14u 0.35s 00:00:01.48 Elapsed: 00:00:00.52
# Mc/sec: 12891.37
//
Query:       EEA20783.1  [L=401]
Description: calcium/calmodulin dependent protein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.7e-75  252.1   0.0    7.5e-75  251.7   0.0    1.1  1  Pkinase         Protein kinase domain
    4.3e-30  104.9   0.0      6e-30  104.4   0.0    1.2  1  Pkinase_Tyr     Protein tyrosine kinase
    6.2e-08   32.3   0.0    9.6e-08   31.7   0.0    1.4  1  Kinase-like     Kinase-like
    9.8e-05   21.3   0.0    0.00018   20.4   0.0    1.3  1  Pkinase_fungal  Fungal protein kinase
    0.00015   21.2   0.0    0.00029   20.3   0.0    1.4  1  Kdo             Lipopolysaccharide kinase (Kdo/WaaP) family
    0.00027   20.9   0.0    0.00043   20.3   0.0    1.4  1  APH             Phosphotransferase enzyme family
  ------ inclusion threshold ------
      0.065   11.4   0.0      0.087   11.0   0.0    1.1  1  SEN1_N          SEN1 N terminal


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  251.7   0.0   2.9e-78   7.5e-75       1     264 []      20     281 ..      20     281 .. 0.93

  Alignments for each domain:
  == domain 1  score: 251.7 bits;  conditional E-value: 2.9e-78
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHS..CTTB--EEEEEEESSEEEEEEE--TTEBHHHHHHHHSS--H CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklk..hpnivrlyevfeekdelylvleyveggeladllerkgslse 97 
                 y++ ++lG Gs+++V ++v+ +tg+ +A K+i+k+ +  +++  v++Ei++lk+++  h+ni++l+++fe+ ++lylv+e++ ggel+d++ rkgs+ e
  EEA20783.1  20 YKTGKTLGAGSYSVVKECVHIDTGRYFAAKVINKRLMAGREH-MVRNEIAVLKRVSmgHQNILTLVDYFETMNNLYLVVELALGGELFDRICRKGSYYE 117
                 78899*********************************9887.9***********99****************************************** PP

                 HHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTE...EEE-SGTTSEESSSSCS..BCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHHHH CS
     Pkinase  98 eeakkiakqilegleylHskgiiHrDlKpeNiLidekge...lKitDFGlakelesssk..ltsfvgtseYlAPEvlkeneyskkvDvWslGvilyell 191
                 ++a ++++ il++++ylH++gi+HrDlKpeN+L+ + ++   l i+DFGl++ +++++   lt+ +gt+ Y+APE+ k+++++k+vD+W++Gvi y ll
  EEA20783.1 118 ADAADLVRAILSAVAYLHDHGIVHRDLKPENLLFRTPEDnadLLIADFGLSRIMDEEQFhvLTTTCGTPGYMAPEIFKKTGHGKPVDIWAIGVITYFLL 216
                 **********************************95333467**************99999************************************** PP

                 HSS-STTTSSHHHHHHHHHHTHHHHHHHCTSHH...HHHTTS-HHHHHHHHHHT-SSGCCSTTHHHHHTSGGG CS
     Pkinase 192 tgkppfsgekgkekvekeldqlekilkilgetkeklpeaseiseeakdllkkllkkdpkkRltaeellqhpyl 264
                 +g +pf    +++    +l++ ++ + + + +   l+++++is++a+d+++++l+ dpk R+ta+e+lqhp++
  EEA20783.1 217 CGYTPFD---RDS----NLEE-MQAILVADYSFTPLEHWRSISQSARDFINRCLTIDPKARITAHEALQHPWI 281
                 *******...333....4444.23344555667789************************************7 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.4   0.0   2.3e-33     6e-30       2     254 ..      21     274 ..      20     278 .. 0.89

  Alignments for each domain:
  == domain 1  score: 104.4 bits;  conditional E-value: 2.3e-33
                  EEEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS..-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHTCT CS
  Pkinase_Tyr   2 elgkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkkl..khpnivkllgvctkeepllivteyvkgGdLlkfLrkkek 97 
                  ++gk+lG+G+++ V e+       ++    a K+++++ ++ +++++ +e++++k++   h+ni+ l+      ++l++v+e++ gG+L + + +k  
   EEA20783.1  21 KTGKTLGAGSYSVVKECVHI----DTGRYFAAKVINKRLMAGREHMVRNEIAVLKRVsmGHQNILTLVDYFETMNNLYLVVELALGGELFDRICRK-- 112
                  5789*************999....7888899999999999999999999******99778**********************************98.. PP

                  TTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEE...TTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSEEEHHHHHHHHH CS
  Pkinase_Tyr  98 ekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlse...nkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekkftsksDvWsfG 192
                   +    d  +++  + ++++yL+++ +vHrdl   N L ++   n    i+DfGL+r + ++++ ++ +++     +mapE++k++   +  D+W+ G
   EEA20783.1 113 GSYYEADAADLVRAILSAVAYLHDHGIVHRDLKPENLLFRTpedNADLLIADFGLSRIM-DEEQFHVLTTTCGTPGYMAPEIFKKTGHGKPVDIWAIG 209
                  8999999********************************976658899*********87.7777777777888889********************** PP

                  HHHHHHHTTSSGTTTTSHHHHHHHHH.HTTEE...S-BBTTSBHHHHHHHHHHT-SSGGGS--HHH CS
  Pkinase_Tyr 193 vllwEiftlgespypglkneevlekl.kegkr...lekpekcpeelyelmkkcweedpeeRptfse 254
                  v+++ +++ g +p+ + +n e ++++  +++    le+ ++++++  +++++c++ dp+ R t +e
   EEA20783.1 210 VITYFLLC-GYTPFDRDSNLEEMQAIlVADYSftpLEHWRSISQSARDFINRCLTIDPKARITAHE 274
                  ****9999.*****9997766666554777762235556667889999*************99776 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.7   0.0   3.7e-11   9.6e-08     104     260 ..      77     232 ..      51     269 .. 0.69

  Alignments for each domain:
  == domain 1  score: 31.7 bits;  conditional E-value: 3.7e-11
  Kinase-like 104 kesiywvvnallllpaasvdl......eilnkvlqkrsethkkletiarlllTlqlirlaanLqakglvhgkftvdnllld...ekgglmlggft..a 190
                  +++i ++v++++ + +  + +      e++  +  k s  ++  +++ r++l +     +a+L+++g+vh +++++nll+     +  l + +f+   
   EEA20783.1  77 HQNILTLVDYFETMNNLYLVVelalggELFDRICRKGSYYEADAADLVRAILSA-----VAYLHDHGIVHRDLKPENLLFRtpeDNADLLIADFGlsR 169
                  455666666666666543322335553444444444444477777777888866.....9********************63225789****996214 PP

  Kinase-like 191 Lvragtkvvlseve..kgfaPpEllgsrggytrknktkmthkldaWqlGlviyriwclklPltlateeakee 260
                  ++   +  vl +++   g+  pE++ +              ++d W++G+  y++ c + P++ + ++ + +
   EEA20783.1 170 IMDEEQFHVLTTTCgtPGYMAPEIFKKT---------GHGKPVDIWAIGVITYFLLCGYTPFDRDSNLEEMQ 232
                  4555555566777777899999999884.........44679*********************998765544 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.0   7.2e-08   0.00018     317     392 ..     129     200 ..     117     207 .. 0.82

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 7.2e-08
  Pkinase_fungal 317 kghrsLflkagiLHrDiSenNilitdskkegerkglLiDLDlakelsddssesgarertGTleFmaievlkgeeHs 392
                      +   L+ + gi+HrD   +N+l+  +  e++   l++D+ l   +++ ++ ++  +  GT+ +ma e+ k++ H 
      EEA20783.1 129 SAVAYLH-DHGIVHRDLKPENLLFRTP--EDNADLLIADFGLSRIMDE-EQFHVLTTTCGTPGYMAPEIFKKTGHG 200
                     3445688.*****************55..556788999*****99997.6666789***************98895 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0   1.1e-07   0.00029     115     167 ..     115     166 ..      87     175 .. 0.86

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 1.1e-07
         Kdo 115 laeelkrallkavgrliaklhragvnHadlyaknillqqeeeeeaeiwliDld 167
                 + e+  + l++a+  ++a lh+ g+ H+dl + n+l+++ e ++a + + D+ 
  EEA20783.1 115 YYEADAADLVRAILSAVAYLHDHGIVHRDLKPENLLFRTPE-DNADLLIADFG 166
                 666777889999****************************8.99999999996 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0   1.7e-07   0.00043     156     200 ..     120     172 ..      43     175 .. 0.73

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 1.7e-07
                 HHHH--S.......SS-EEEE-SS-SGGGEEEC...TTEEEEE---TT-EEEE CS
         APH 156 laallpg.......elptvllHgDlhpgNllvd.pddgrvtGviDfedaglgp 200
                  a+l+++         +++++H+Dl+p Nll++ p+d+    + Df+++++++
  EEA20783.1 120 AADLVRAilsavayLHDHGIVHRDLKPENLLFRtPEDNADLLIADFGLSRIMD 172
                 22222333444444778*****************5555554599***999986 PP

>> SEN1_N  SEN1 N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   3.4e-05     0.087     394     471 ..     231     306 ..     219     324 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 3.4e-05
      SEN1_N 394 adtivdvalktkpedkanselskaareviekalalDikslaeelekLsagkqe.ilqsgvlrrsknlWkalykalssgd 471
                  + i+  +++ +p  +++ ++s++ar+ i+++l+ D k+ ++++e+L++   + +++s++ ++ ++l  ++ k++++++
  EEA20783.1 231 MQAILVADYSFTP-LEHWRSISQSARDFINRCLTIDPKARITAHEALQHP--WiSNDSFSKQQGEDLLPTVKKNFNARR 306
                 4455545665566.56******************************9987..323444444666666666666666554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (401 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       571  (0.0318478); expected 358.6 (0.02)
Passed bias filter:                      520  (0.0290033); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.42
# Mc/sec: 2875.89
//
Query:       EEA20784.1  [L=322]
Description: AMMECR1 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.4e-41  140.3   0.0    9.8e-41  139.1   0.0    1.5  2  AMMECR1   AMMECR1


Domain annotation for each model (and alignments):
>> AMMECR1  AMMECR1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0      0.28     5e+03       1      19 [.       7      25 ..       7      40 .. 0.71
   2 !  139.1   0.0   5.5e-45   9.8e-41      19     149 ..     114     255 ..      96     264 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 0.28
                HHHHHHHHHHHTTSS-S-H CS
     AMMECR1  1 lklareaieealkeekkle 19
                + +++e++++ +k+e++ +
  EEA20784.1  7 CFYCFETLAASYKDEEPPS 25
                5689999987777777655 PP

  == domain 2  score: 139.1 bits;  conditional E-value: 5.5e-45
                 H...H---HHHHSEEEEEEEEE....EE..CCECCCECEEEEEEHHHHHHHHHHHHHHT-TTS----HHHHTTEEEEEEEE---EE--.GGG--TTT-E CS
     AMMECR1  19 e...eeakeelkekaglFVtlk....ekkgeLRGCiGtleperpLaeevaenAlaaAfeDpRFspvtaeElpeleveVsvLtepepiv.ledlevgkhG 109
                 e   ++ +++ +e ++lFVt++    +++++LRGCiGt+e +++L  +++e++l +Af+D+RFsp+  + lp+l++  ++L+++ep++ + d+e+g+hG
  EEA20784.1 114 EdtsSQPPSSAEEAYPLFVTWNlisrHGHKSLRGCIGTFE-AQKLSYGLKEYSLISAFNDTRFSPIPVSQLPRLSCFLTLLSNFEPCAdPLDWELGTHG 211
                 24335556688999********97554555**********.9*********************************************54677******* PP

                 EEEE.E...TTEEEEE-THHHHHTT--HHHHHHHHHHHHTS-TT CS
     AMMECR1 110 liie.k...gsrsatlLPqvaveqgwdkeeflasllrKaglrpd 149
                 + i+     +++ at+LP+vaveqgw+kee+++sl+rKag++++
  EEA20784.1 212 IRISfIhrnRRYGATYLPDVAVEQGWTKEETIESLMRKAGWSGS 255
                 **9863344599*****************************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (322 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       642  (0.0358079); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2309.25
//
Query:       EEA20785.1  [L=607]
Description: regulatory factor Sgt1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.4e-98  330.9  17.0    8.7e-89  298.5   0.0    2.0  2  SGT1         SGT1 protein
  ------ inclusion threshold ------
       0.18   11.6   0.2       0.46   10.3   0.2    1.6  1  eIF-1a       Translation initiation factor 1A / IF-1
        1.4    9.4   4.0       0.99    9.9   0.3    2.6  3  GlutR_dimer  Glutamyl-tRNAGlu reductase, dimerisation domain


Domain annotation for each model (and alignments):
>> SGT1  SGT1 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  298.5   0.0   1.5e-92   8.7e-89       1     305 [.      29     338 ..      29     347 .. 0.91
   2 !   32.2  15.5   6.7e-12     4e-08     393     578 ..     371     561 ..     335     565 .. 0.72

  Alignments for each domain:
  == domain 1  score: 298.5 bits;  conditional E-value: 1.5e-92
        SGT1   1 veYklflkqedssdke.....keeeklqelleeilakvapllveYiWqkdpFnLkvrtekgdlpahlgGvtkfGdnieDEWFiVyLlkeitkefpelva 94 
                 veY+l+l ++d + ++     +++++lqe+++++ + v+ ll++YiWq++ F+L++ +  ++ ++ l G+t+fGd+ieDEW iVyLl+e+tk+ ++l +
  EEA20785.1  29 VEYSLYLLSSDPAPAStdtivQTRARLQEVQKSASELVKGLLTDYIWQREAFSLEIAK--ENDISYLRGRTNFGDSIEDEWVIVYLLRELTKKHQDLWI 125
                 89999988555443331112278899*****************************998..677899********************************* PP

        SGT1  95 rvedndgeflLieaaevlPkWlnPdtsenrvfiykGelhiipksskssevelkakepslsqalellsknpeetlasesiqsaikkrlkgYpekikeslh 193
                 rv d+dgeflL+eaa  lP+Wl+P+ +++rv+i +G+l ii+ ++++++    +++++l+++l++ ++++e++l s+si++    rl+ Yp++ike+lh
  EEA20785.1 126 RVVDSDGEFLLVEAASSLPDWLEPEVADHRVWINNGDLVIIKPKNDRKR---VMEKITLEESLKIAAHETERLLRSSSIEEEAFYRLRKYPQQIKENLH 221
                 *****************************************99888886...7999******************************************* PP

        SGT1 194 rahvyvPasvaavLkqrPsLvapAVqaFylRdpvdlkacrt....mktFppetrvltsvtftrclYAqLvqqkftpdkrsgyklpsrsdpe.ykaaelG 287
                 +a v +P +va++L+q+P  +++AV aFy Rdp++l+++r+       Fpp + v++sv+ftr  YAq+  q f p+   + ++p+ +d + +++ae G
  EEA20785.1 222 CALVTIPRKVAYLLHQKPAYISAAVDAFYTRDPISLRTLRArgkdHLLFPPSDFVTVSVRFTRVGYAQVKSQDFPPPTSWAQSMPPPADDDkFAKAETG 320
                 **************************************9972222457*******************************9999**9965555******* PP

        SGT1 288 mklAhGfEiLcskakkas 305
                 mk+++GfE+L s  ++++
  EEA20785.1 321 MKVSCGFEMLLSDPQNQD 338
                 ***********9887754 PP

  == domain 2  score: 32.2 bits;  conditional E-value: 6.7e-12
        SGT1 393 ppedddsWLeiseeeLdkllqeragekelveesskeeeasydleevtksmkaFldkvS.sheGaelPe...............skeekevsfdvdsflk 475
                  ++dd+ WL+is e+Ld+ l+ +ag++++      +++a+ +l++++ + ++Fl+  S +++G++l +               ++ee +++fd+++f+k
  EEA20785.1 371 MQQDDEGWLDISFEDLDRELKGEAGKNKEA-GAFGDQSAQENLQRIVARFEEFLKDDSaNFDGVDLYNsdtdneageeeeassEDEEGDLKFDEEEFIK 468
                 6899*********************99999.6777888999*************876538******554444444444445447777788888888888 PP

        SGT1 476 alekllgskieeeldsddldedssedsdeedeedeeeeeaeeeskeeekeslksYmdqmdeELaqttvgksFekkkkkkekakkkeekeetseekee.d 573
                 +++++       +     l +  ++ ++ +       ee +++++++  +++++ + qm+ EL  t + +  +++ ++k    k + k++++ e+++ d
  EEA20785.1 469 YMKEMRMDPSGVD-----LRTRFDKAMKGKV------EELDSADEDDDIREIEELSRQMEAELRPTGILNVSNQEADQKPAVVKGKGKQKAKPEDFDfD 556
                 8887755442222.....3222223333222......2347788899999*****************99988888888888888887777776664313 PP

        SGT1 574 eeefe 578
                 ee+ +
  EEA20785.1 557 EEDPA 561
                 44433 PP

>> eIF-1a  Translation initiation factor 1A / IF-1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.2   7.7e-05      0.46      37      54 ..     154     170 ..     148     178 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 7.7e-05
                 CT----TT-EEEEEE-TT CS
      eIF-1a  37 nkiwikrGdyVlVelspy 54 
                 +++wi+ Gd V++++ ++
  EEA20785.1 154 HRVWINNGDLVIIKP-KN 170
                 79************9.33 PP

>> GlutR_dimer  Glutamyl-tRNAGlu reductase, dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0      0.52   3.1e+03      23      41 ..      45      63 ..      42      75 .. 0.72
   2 ?   -3.5   0.2       2.5   1.5e+04      35      49 ..     186     200 ..     182     211 .. 0.71
   3 ?    9.9   0.3   0.00017      0.99      11      65 ..     464     516 ..     462     538 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.52
                 HHHHHHHHHHHHHHHHHHH CS
  GlutR_dimer 23 vptIkalrekaeeireeel 41
                 ++tI++ r++++e++++  
   EEA20785.1 45 TDTIVQTRARLQEVQKSAS 63
                 5688888888888877654 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 2.5
                  HHHHHHHHHHHS-S. CS
  GlutR_dimer  35 eireeeleralkkla 49 
                  +i+++e er+l+  +
   EEA20785.1 186 KIAAHETERLLRSSS 200
                  688889999888655 PP

  == domain 3  score: 9.9 bits;  conditional E-value: 0.00017
                  HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS-S..--------TTHHHHH CS
  GlutR_dimer  11 eefeawlkslevvptIkalrekaeeireeeleralkklaldgedreelekltrsl 65 
                  eef + +k+++++p  ++lr+++++  +  +e++ +    +++d +e+e+l+r++
   EEA20785.1 464 EEFIKYMKEMRMDPSGVDLRTRFDKAMKGKVEELDSAD--EDDDIREIEELSRQM 516
                  69********************************9975..6888888*****987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (607 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       827  (0.0461264); expected 358.6 (0.02)
Passed bias filter:                      507  (0.0282782); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.67u 0.31s 00:00:00.98 Elapsed: 00:00:00.45
# Mc/sec: 4009.06
//
Query:       EEA20786.1  [L=1242]
Description: spindle-pole body protein (Pcp1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      2e-24   85.5   4.5      2e-24   85.5   4.5   15.1 13  Cnn_1N          Centrosomin N-terminal motif 1
    4.7e-22   78.4   1.5    4.7e-22   78.4   1.5    3.5  2  PACT_coil_coil  Pericentrin-AKAP-450 domain of centrosomal ta
    8.3e-05   22.8   9.6    8.3e-05   22.8   9.6   12.0 12  TMF_TATA_bd     TATA element modulatory factor 1 TATA binding
    0.00023   21.7 168.9       0.17   12.3  28.1    8.2  8  Fez1            Fez1
  ------ inclusion threshold ------
       0.41   11.2   3.0        8.5    7.0   3.0    3.6  1  TAF8_C          Transcription factor TFIID complex subunit 8 
        8.4    6.9   6.6        1.4    9.4   0.6    2.8  2  DUF150          RimP N-terminal domain


Domain annotation for each model (and alignments):
>> Cnn_1N  Centrosomin N-terminal motif 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.5   4.5   6.9e-28     2e-24       1      72 [.     203     274 ..     203     275 .. 0.98
   2 ?   -5.9  13.0         6   1.8e+04      22      65 ..     315     361 ..     278     368 .. 0.59
   3 ?  -10.5  18.9         6   1.8e+04      35      68 ..     402     448 ..     337     452 .. 0.68
   4 !    5.6   3.1     0.006        18      28      65 ..     440     477 ..     436     485 .. 0.84
   5 ?   -6.7  15.2         6   1.8e+04      35      73 .]     522     569 ..     453     574 .. 0.81
   6 ?    2.3   4.0     0.062   1.8e+02      24      70 ..     563     609 ..     561     624 .. 0.89
   7 ?   -7.7  10.6         6   1.8e+04      56      56 ..     648     648 ..     583     704 .. 0.50
   8 ?   -0.5   3.3      0.47   1.4e+03      36      64 ..     715     744 ..     699     751 .. 0.73
   9 ?    1.7   1.0     0.096   2.9e+02      37      68 ..     760     791 ..     751     801 .. 0.56
  10 ?   -2.5   4.3         2   5.9e+03      23      43 ..     830     856 ..     820     905 .. 0.56
  11 ?    0.6   5.4      0.22   6.6e+02      25      71 ..     931     976 ..     895     978 .. 0.89
  12 ?   -2.7  11.2       2.3   6.8e+03      18      60 ..     959    1025 ..     954    1065 .. 0.78
  13 ?   -2.1   3.9       1.5   4.6e+03      21      61 ..    1056    1102 ..    1031    1121 .. 0.61

  Alignments for each domain:
  == domain 1  score: 85.5 bits;  conditional E-value: 6.9e-28
      Cnn_1N   1 TlrEqeeqidkLkKENFdLKLriyfLeerleklseeqkeellkenielkveveslqkelkekkkllreaeka 72 
                 +l+Eqe+ i+kL+KENF+LKL+i++Lee+l+k ++  ++++lken+elkv + ++q+e+ ++kk l++ae++
  EEA20786.1 203 SLKEQENAINKLDKENFGLKLKIHYLEEQLKKAGPGYNQAALKENTELKVARITMQQEISRYKKGLHQAERD 274
                 79********************************************************************97 PP

  == domain 2  score: -5.9 bits;  conditional E-value: 6
      Cnn_1N  22 riyfLeerleklse...eqkeellkenielkveveslqkelkekkkl 65 
                 +++ L+e+l + ++   +++e l +e ++l++++ + ++ +++k+++
  EEA20786.1 315 QVNNLQEELRNVKDkdsDEVERLRDEIVDLETTLREKERIIDAKDEE 361
                 34445555555554555666666666666666666666666666655 PP

  == domain 3  score: -10.5 bits;  conditional E-value: 6
      Cnn_1N  35 e.............eqkeellkenielkveveslqkelkekkkllre 68 
                               eqke++++++ el++e+++   + k + ++l+e
  EEA20786.1 402 AdareanrnreqaiEQKEKAEENLKELQDEMANKSFSTKGLSRQLEE 448
                 34444454444556777777777777777777777777777766665 PP

  == domain 4  score: 5.6 bits;  conditional E-value: 0.006
      Cnn_1N  28 erleklseeqkeellkenielkveveslqkelkekkkl 65 
                 + l +  ee  e+l+ke+ +l++e  +l+++  +k+++
  EEA20786.1 440 KGLSRQLEERAEDLEKELNQLRDEYNDLKQDYAAKERR 477
                 5677778899*********************9999875 PP

  == domain 5  score: -6.7 bits;  conditional E-value: 6
      Cnn_1N  35 e.........eqkeellkenielkveveslqkelkekkkllreaekai 73 
                 e         ++ke l      l +e +slq+el + +  +r++e++i
  EEA20786.1 522 EvlddldrktDEKELLQTRHHALTDESASLQRELANAQSTIRRLEQEI 569
                 233334446567777777778899999999999999999999998875 PP

  == domain 6  score: 2.3 bits;  conditional E-value: 0.062
      Cnn_1N  24 yfLeerleklseeqkeellkenielkveveslqkelkekkkllreae 70 
                   Le+++e  +++ +++ ++ +++ ++e+e l  e+ ++++++++ e
  EEA20786.1 563 RRLEQEIEDEKQRGMDNNHDLRTQHREEIERLSEEIMSLHQEIEDKE 609
                 56899999999999999999999999999999999999999999876 PP

  == domain 7  score: -7.7 bits;  conditional E-value: 6
      Cnn_1N  56 q 56 
                 q
  EEA20786.1 648 Q 648
                 3 PP

  == domain 8  score: -0.5 bits;  conditional E-value: 0.47
      Cnn_1N  36 eqkeellkenie.lkveveslqkelkekkk 64 
                 +  ee+lke ++ l++ev+ l+ +l+e k+
  EEA20786.1 715 RREEEILKEKVQaLEDEVAILRASLQEEKE 744
                 456777777776589999999999999876 PP

  == domain 9  score: 1.7 bits;  conditional E-value: 0.096
      Cnn_1N  37 qkeellkenielkveveslqkelkekkkllre 68 
                 q ++++ e+ +l+++++s   el++++ +  e
  EEA20786.1 760 QLQKVMTERQNLRDQLASANVELHNLRTSTAE 791
                 44444555555555555555555555444443 PP

  == domain 10  score: -2.5 bits;  conditional E-value: 2
      Cnn_1N  23 iyfLeerleklse.........eqkeellk 43 
                 +   e++l++l++         +++e++l+
  EEA20786.1 830 L---ENELQRLKDektslmdarKSIEDALN 856
                 2...22222222222244444444444444 PP

  == domain 11  score: 0.6 bits;  conditional E-value: 0.22
      Cnn_1N  25 fLeerleklseeqkeellkenielkveveslqkelkekkkllreaek 71 
                  L+++l+  ++   + ll+   e k  + +l++ + e+++ l+ea+ 
  EEA20786.1 931 LLRQNLDDARK-REKTLLEREGEHKKSIRELRNRISELEEALHEAQM 976
                 68888888888.777888889999999***********999999986 PP

  == domain 12  score: -2.7 bits;  conditional E-value: 2.3
      Cnn_1N   18 dLKLriyfLeerleklse........................eqkeellkenielkveveslqkelk 60  
                   L+ ri +Lee+l++ +                         +  +e++k  +elk+++ +l+++  
  EEA20786.1  959 ELRNRISELEEALHEAQMqklnipsparsssdglhedlramrSRLKEAHKIVMELKTKNRELERSAM 1025
                  5899999999999999989999999999777777766655555556666666666666666666544 PP

  == domain 13  score: -2.1 bits;  conditional E-value: 1.5
      Cnn_1N   21 LriyfLeerleklse......eqkeellkenielkveveslqkelke 61  
                  L+++ L+  l +++e      ++++++ +e   l+++v sl  ++++
  EEA20786.1 1056 LQVNDLKASLRRIREersmavKKSDKASQECEALQERVDSLMEDVNA 1102
                  33344555555555555566655666666666666666666665555 PP

>> PACT_coil_coil  Pericentrin-AKAP-450 domain of centrosomal targeting protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.2       2.4   7.2e+03      19      65 ..     481     522 ..     468     526 .. 0.62
   2 !   78.4   1.5   1.6e-25   4.7e-22       1      83 []    1127    1203 ..    1127    1203 .. 0.98

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 2.4
  PACT_coil_coil  19 Lllqlevfqacnkadlrllarigvelkkkkkskeeekrrkprrklrs 65 
                     L+ qle+ q+   a+l +l++   +    + +++ ++r ++  +l+ 
      EEA20786.1 481 LEGQLEEVQQERAAELDSLRD---KA--DSAEQYLAERDEALGRLKE 522
                     344555555555555555554...44..3335666666666666665 PP

  == domain 2  score: 78.4 bits;  conditional E-value: 1.6e-25
  PACT_coil_coil    1 rleReeslRkdlayqKrYLllqlevfqacnkadlrllarigvelkkkkkskeeekrrkprrklrsaatavraiaRmrvlarkW 83  
                      rl+Ree++R+dla++K  ++l  +v+ acn+adlr++a++g++       +e++k + +rrk r+a +av+a++Rm++++++W
      EEA20786.1 1127 RLRREEKFRRDLAWSKGLMELGEQVRVACNEADLRMIAEMGIHT------PEPKKVHDARRKIRTAGLAVMATVRMQRMSQEW 1203
                      899*****************************************......789****************************** PP

>> TMF_TATA_bd  TATA element modulatory factor 1 TATA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   4.8       1.1   3.3e+03      37      76 ..     249     288 ..     197     295 .. 0.56
   2 ?   -2.9  19.9       2.6   7.9e+03      11     109 ..     258     349 ..     248     369 .. 0.59
   3 ?    4.4  19.5     0.014        42      19     111 ..     374     467 ..     369     471 .. 0.87
   4 ?    0.9  17.2      0.17   5.1e+02      22     104 ..     444     527 ..     442     539 .. 0.87
   5 !    5.8  12.6    0.0053        16      15      96 ..     556     635 ..     544     640 .. 0.88
   6 ?   -2.8   9.6       2.4   7.3e+03      30      92 ..     682     744 ..     666     748 .. 0.85
   7 !    5.4   4.5    0.0067        20      14      58 ..     768     812 ..     749     826 .. 0.65
   8 ?    1.5   4.5      0.11   3.4e+02      23      61 ..     829     868 ..     822     877 .. 0.64
   9 !   22.8   9.6   2.8e-08   8.3e-05       7     110 ..     870     973 ..     864     979 .. 0.93
  10 ?   -1.0   1.1      0.65   1.9e+03      33      62 ..     994    1023 ..     985    1039 .. 0.47
  11 ?    3.6   8.7     0.026        77      14      81 ..    1044    1112 ..    1034    1127 .. 0.80
  12 ?   -2.4   0.5       1.9   5.6e+03       8      34 ..    1200    1226 ..    1192    1232 .. 0.64

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 1.1
  TMF_TATA_bd  37 rleaerdeareeivklmkeneelkelkkeleelekeleel 76 
                  +l+  r ++++ei +  k  ++ ++  + ++ + +el+e 
   EEA20786.1 249 ELKVARITMQQEISRYKKGLHQAERDLEAYRLQLQELREK 288
                  4444444444444444443333333333333333333333 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 2.6
  TMF_TATA_bd  11 vqlverlsseirrlEgElaslkeelerlea..erdeareeivklm.keneelkelkkeleelekeleelqeryetlLellGeksEeveELraDvaDlK 105
                  +q ++r ++ +++ E +l++++ +l++l +  +r++a e i + m    ee ++ ++++++l++el+           +  + s+eve Lr++++Dl 
   EEA20786.1 258 QQEISRYKKGLHQAERDLEAYRLQLQELREkaKRRQADEAIQREMdYMREEIATREAQVNNLQEELR----------NVKDKDSDEVERLRDEIVDLE 345
                  4556666666666666666666666666431144555555554441223444444444444444444..........444566777777777777776 PP

  TMF_TATA_bd 106 emyk 109
                  + ++
   EEA20786.1 346 TTLR 349
                  6655 PP

  == domain 3  score: 4.4 bits;  conditional E-value: 0.014
  TMF_TATA_bd  19 seirrlEgElaslkeelerleaerdeareeivklmkeneelkelkkeleelekel.eelqeryetlLellGeksEeveELraDvaDlKemykeq 111
                   ++ +lE+El  ++++l++++   ++a+++  +  ++ e+  e+k++ ee  kel +e+ ++  ++  l  + +E+ e+L+++++ l++ y+++
   EEA20786.1 374 NAVAELEAELDRARQQLAEFQDDLEKAKADAREANRNREQAIEQKEKAEENLKELqDEMANKSFSTKGLSRQLEERAEDLEKELNQLRDEYNDL 467
                  678899*************************999999999888888877666665157999999*************************99875 PP

  == domain 4  score: 0.9 bits;  conditional E-value: 0.17
  TMF_TATA_bd  22 rrlEgElaslkeelerleaerdeareeivklmkeneelkelkkeleelek.eleelqeryetlLellGeksEeveELraDvaDl 104
                  r+lE   + l++el++l  e ++++++ ++  ++ e l+ + +e+++ ++ el++l+++ +++ + l e++E    L++ ++Dl
   EEA20786.1 444 RQLEERAEDLEKELNQLRDEYNDLKQDYAAKERREEMLEGQLEEVQQERAaELDSLRDKADSAEQYLAERDEALGRLKEVLDDL 527
                  7888889999999999999999999999999999999998888887665459**********************9999999987 PP

  == domain 5  score: 5.8 bits;  conditional E-value: 0.0053
  TMF_TATA_bd  15 erlsseirrlEgElaslkee.lerleaerdeareeivklmkeneelkelkkeleelekeleelqeryetlLellGeksEeveE 96 
                   + +s+irrlE E++  k++ + +    r + reei +l+   ee  +l++e+e+ e +++  q+r e++   l+ ++++ eE
   EEA20786.1 556 ANAQSTIRRLEQEIEDEKQRgMDNNHDLRTQHREEIERLS---EEIMSLHQEIEDKEGQFALDQDRWESAKRTLQSQKDRAEE 635
                  5679**********9877763777888899******9998...899999*******************************999 PP

  == domain 6  score: -2.8 bits;  conditional E-value: 2.4
  TMF_TATA_bd  30 slkeelerleaerdeareeivklmkeneelkelkkeleelekeleelqeryetlLellGeksE 92 
                  ++ke    ++++r++++e+  ++++  eel+   +e e l++++++l+++   l   l+e +E
   EEA20786.1 682 QIKELADDITSKRQTISEQRSEMLTIKEELRVGRREEEILKEKVQALEDEVAILRASLQEEKE 744
                  677778889999999999999999999999999999999999999999999888888888877 PP

  == domain 7  score: 5.4 bits;  conditional E-value: 0.0067
  TMF_TATA_bd  14 verlsseirrlEgElaslkeelerleaerdeareeivklmkenee 58 
                   ++l  ++ +  +El++l+++ +++eaerd +++e+ ++ ++++ 
   EEA20786.1 768 RQNLRDQLASANVELHNLRTSTAEVEAERDLLQNELNQIQSKSNG 812
                  356667777777777777777777777777777777766665554 PP

  == domain 8  score: 1.5 bits;  conditional E-value: 0.11
  TMF_TATA_bd  23 rlEgElaslkeelerleaerdeareeivklm.keneelke 61 
                  rlE+El+ lk+e ++l   r+++++ + + + +++ e ++
   EEA20786.1 829 RLENELQRLKDEKTSLMDARKSIEDALNAEIeRSTAEENR 868
                  7899999999999999988887766554333122223333 PP

  == domain 9  score: 22.8 bits;  conditional E-value: 2.8e-08
  TMF_TATA_bd   7 agpsvqlverlsseirrlEgElaslkeelerleaerdeareeivklmkeneelkelkkeleelekeleelqeryetlLellGeksEeveELraDvaDl 104
                  +g  vql ++l +++  ++ Ela +k+++ +le+  +e+++   +    n e ++ ++++  l+++l++ ++r++tlLe  Ge +  + ELr+ +++l
   EEA20786.1 870 SGELVQLQDKLRAALGGRDRELAVAKSQVRQLERRISELNAIAEQQQPVNAEGSSVATDIPLLRQNLDDARKREKTLLEREGEHKKSIRELRNRISEL 967
                  56779999********************************999999999************************************************* PP

  TMF_TATA_bd 105 Kemyke 110
                   e ++e
   EEA20786.1 968 EEALHE 973
                  998875 PP

  == domain 10  score: -1.0 bits;  conditional E-value: 0.65
  TMF_TATA_bd   33 eelerleaerdeareeivklmkeneelkel 62  
                   e+l  + +  +ea + +++l ++n el+++
   EEA20786.1  994 EDLRAMRSRLKEAHKIVMELKTKNRELERS 1023
                   333333333344444444444444444333 PP

  == domain 11  score: 3.6 bits;  conditional E-value: 0.026
  TMF_TATA_bd   14 verlsseirrlEgElaslkeelerleaerdeareeivklmkeneelkelkke.leelekeleelqerye 81  
                    e+l  ++ ++E +++ lk +l r+ +er+ a +   k ++e+e+l+e  ++ +e+++++++  +++ +
   EEA20786.1 1044 AESLALKLSEKELQVNDLKASLRRIREERSMAVKKSDKASQECEALQERVDSlMEDVNAKVNRKNRHDK 1112
                   57888999999999********************99999999999987655416777777777665544 PP

  == domain 12  score: -2.4 bits;  conditional E-value: 1.9
  TMF_TATA_bd    8 gpsvqlverlsseirrlEgElaslkee 34  
                   +++ +  ++++ ++rr  +El++ +++
   EEA20786.1 1200 SQEWSKAKKIGESLRRAKNELSMKRDS 1226
                   444455566777778888887777665 PP

>> Fez1  Fez1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9  16.7     0.022        65      46     151 ..     203     330 ..     196     338 .. 0.57
   2 !   12.3  28.1   5.7e-05      0.17      20     163 ..     327     477 ..     323     480 .. 0.76
   3 !   10.6  27.8   0.00019      0.58      29     177 ..     476     630 ..     466     654 .. 0.77
   4 !    6.8  14.9    0.0028       8.5      49     154 ..     642     749 ..     627     753 .. 0.70
   5 ?    3.1  12.8     0.037   1.1e+02      72     161 ..     758     847 ..     746     869 .. 0.65
   6 !    6.6  14.1    0.0032       9.6      10     163 ..     871    1023 ..     869    1029 .. 0.72
   7 !    8.3  16.2   0.00098       2.9      32     152 ..    1021    1136 ..    1011    1142 .. 0.79
   8 ?   -0.2   0.3      0.39   1.2e+03     124     152 ..    1200    1228 ..    1159    1241 .. 0.54

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.022
        Fez1  46 kleekeeeikeleesleektlelevcenelqrk........kseaellrekvekleeelkelreelselsleeeeaalesdeakaqrqe.......... 126
                 +l+e+e++i++l+++    +l+++ +e++l+++         +e++ l+    ++++e+++ ++ l++++++ e  +l+ +e +++ ++          
  EEA20786.1 203 SLKEQENAINKLDKENFGLKLKIHYLEEQLKKAgpgynqaaLKENTELKVARITMQQEISRYKKGLHQAERDLEAYRLQLQELREKAKRrqadeaiqre 301
                 566777777777777777777777777777777777666664555555555666777777777777776665555554444444444431123333333 PP

        Fez1 127 ....aeeleelkreverlraeLkeerqkk 151
                     +ee+++ +++v++l++eL++ ++k 
  EEA20786.1 302 mdymREEIATREAQVNNLQEELRNVKDKD 330
                 34445556666666666666666655554 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 5.7e-05
        Fez1  20 kdsqaevtqkl.seivalkaqlrelrakleekeeeikeleesleektlelevcenelqrkkseaellrekvekleeelkelreelselsleeeeaales 117
                 kd  ++  ++l +eiv l ++lre +  +++k+eei+ l+e   + ++ + ++e+el+r++++   +++ +ek++++ +e  ++ +++ +++e+a+++ 
  EEA20786.1 327 KDKDSDEVERLrDEIVDLETTLREKERIIDAKDEEIEILKEDDGQDSNAVAELEAELDRARQQLAEFQDDLEKAKADAREANRNREQAIEQKEKAEENL 425
                 66666655555279**********************************************999999999999999998888666665555555444333 PP

        Fez1 118 deakaqrqe.....aeeleelkreverlraeLkeerqkkeeqassFe.qERr 163
                 +e + + ++     +  +++l+++ e l++eL++ r++ ++ +++++ +ERr
  EEA20786.1 426 KELQDEMANksfstKGLSRQLEERAEDLEKELNQLRDEYNDLKQDYAaKERR 477
                 3333332224444466677888888889999999999988888888525775 PP

  == domain 3  score: 10.6 bits;  conditional E-value: 0.00019
        Fez1  29 klseiv..alkaqlrelrakleekeeeikeleesleektle...levcenelqrkkseaellrekvekleeelkelreelselsleeeeaalesdeaka 122
                 + +e++  +l    +e  a+l++  ++++++e+ l e+++    l+++ ++l+rk++e+ell+ + ++l +e ++l++el++++++ ++ ++e ++ k+
  EEA20786.1 476 RREEMLegQLEEVQQERAAELDSLRDKADSAEQYLAERDEAlgrLKEVLDDLDRKTDEKELLQTRHHALTDESASLQRELANAQSTIRRLEQEIEDEKQ 574
                 4455552234555567778899999999999999998888833345555789999*************************9988877777766666555 PP

        Fez1 123 q..rqeaeeleelkreverlraeLkeerqkkeeqassFeqERrtWqeeKekVirYqk 177
                 +   ++++  ++ ++e+erl +e++  +q+ e+++ +F+ +   W++ K + ++ qk
  EEA20786.1 575 RgmDNNHDLRTQHREEIERLSEEIMSLHQEIEDKEGQFALDQDRWESAK-RTLQSQK 630
                 5223446777889999*****************************9988.5566665 PP

  == domain 4  score: 6.8 bits;  conditional E-value: 0.0028
        Fez1  49 ekeeeikeleesleektlele.vcenelqrkkseaellrekvekleeelkelreelselsleeeeaalesdeakaqrqe....aeeleelkreverlra 142
                 ++ e+++++e +++ ++++l+ v+++e +r+ +e+ +l+ ++++l +++++ r+++se+ +e  +    ++e ++ r+e    +e++++l+ ev+ lra
  EEA20786.1 642 RTIEKLQDVELTISGRAAKLQdVIDSEKERHLQEEAVLSRQIKELADDITSKRQTISEQRSEMLTI---KEELRVGRREeeilKEKVQALEDEVAILRA 737
                 455666777777777777765267889999999999999999999999999999988855443333...333333333334568899999999999999 PP

        Fez1 143 eLkeerqkkeeq 154
                 +L+ee++ ++++
  EEA20786.1 738 SLQEEKEYSKAK 749
                 999999876655 PP

  == domain 5  score: 3.1 bits;  conditional E-value: 0.037
        Fez1  72 enelqrkkseaellrekvekleeelkelreelselsleeeeaalesdeakaqrqeaeeleelkreverlraeLkeerqkkeeqassFeqE 161
                 +++lq+  +e ++lr+++ +++ el++lr++ +e+++e++  ++e ++ + + +  ++ + +k e+ +++ +L++e q+ +++++s  + 
  EEA20786.1 758 DSQLQKVMTERQNLRDQLASANVELHNLRTSTAEVEAERDLLQNELNQIQSKSNGINNFDYEKVELRKVKLRLENELQRLKDEKTSLMDA 847
                 566777777777777777777777777777777777666666666666666666666666666666666666666666655554444433 PP

  == domain 6  score: 6.6 bits;  conditional E-value: 0.0032
        Fez1   10 GEislLKqQLkdsqaevtqklseivalkaqlrelrakleeke...eeikeleesleektlelevcenelqrkkseaellrekvekleeelkelreel 103 
                  GE+  L   L   +a +  +  e+   k+q+r+l+ +++e +   e+ + ++++ ++ ++++  + ++l+ +++++++l e+ ++ ++ ++elr+++
  EEA20786.1  871 GELVQLQDKL---RAALGGRDRELAVAKSQVRQLERRISELNaiaEQQQPVNAEGSSVATDIPLLRQNLDDARKREKTLLEREGEHKKSIRELRNRI 964 
                  5555555554...4779999**************98766654222788889999999999************999999*****************99 PP

        Fez1  104 selsleeeeaalesdeakaqrqeaeeleelkreverlraeLkeerqkk.eeqassFeqERr 163 
                  sel++  +ea+  +++ +    ++++++ l++++  +r++Lke ++   e ++++ e ER 
  EEA20786.1  965 SELEEALHEAQ--MQKLNIPSPARSSSDGLHEDLRAMRSRLKEAHKIVmELKTKNRELERS 1023
                  99765544443..333334444466777777777777777777666431334444455554 PP

  == domain 7  score: 8.3 bits;  conditional E-value: 0.00098
        Fez1   32 eivalkaq.lrelrakleekeeeikeleesleektlelevcenelqrkkseaellrekvekleeelkelreelselsleeeeaalesdeakaqrqea 127 
                  e  a+ka+  ++l++ l+++  e+++l  +l+ek+l+++ +++ l+r ++e ++  +k +k+++e++ l+e++ +l ++ +     ++ ++++r+  
  EEA20786.1 1021 ERSAMKAEdRKDLHELLKSSTLEAESLALKLSEKELQVNDLKASLRRIREERSMAVKKSDKASQECEALQERVDSLMEDVN-----AKVNRKNRH-D 1111
                  4456777525789999999****************************************************9888654322.....222223333.4 PP

        Fez1  128 eeleelkreverlraeLkeerqkke 152 
                  +e++ l +e+  lr++L+ e++ + 
  EEA20786.1 1112 KEIRGLGKEIVWLRTRLRREEKFRR 1136
                  7899*************99987654 PP

  == domain 8  score: -0.2 bits;  conditional E-value: 0.39
        Fez1  124 rqeaeeleelkreverlraeLkeerqkke 152 
                   qe++++++  +++ r ++eL+++r+++ 
  EEA20786.1 1200 SQEWSKAKKIGESLRRAKNELSMKRDSQR 1228
                  22233333333444444444444433332 PP

>> TAF8_C  Transcription factor TFIID complex subunit 8 C-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   3.0    0.0028       8.5      26      49 .]     405     428 ..     397     428 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0028
      TAF8_C  26 tdpkkirekaaeqsrlaekaLrkL 49 
                 ++  ++re+a+eq+ +ae++L+ L
  EEA20786.1 405 REANRNREQAIEQKEKAEENLKEL 428
                 677899***************876 PP

>> DUF150  RimP N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.6   0.00048       1.4      12      54 ..     646     688 ..     641     700 .. 0.90
   2 ?   -1.8   0.8       1.5   4.4e+03       7      59 ..    1045    1096 ..    1043    1100 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00048
      DUF150  12 elvdvelskegrgrvlriyidkdggvtlddcekvSraisalLd 54 
                 +l dvel+ +gr ++l+ +id+++   l++ + +Sr+i++l d
  EEA20786.1 646 KLQDVELTISGRAAKLQDVIDSEKERHLQEEAVLSRQIKELAD 688
                 689***********************************99866 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 1.5
      DUF150    7 eslglelvdvelskegrgrvlriyidkdggvtlddcekvSraisalLdvedpi 59  
                  esl l+l + el+ +  ++ lr  i ++  + + +  k S++ +al +++d++
  EEA20786.1 1045 ESLALKLSEKELQVNDLKASLR-RIREERSMAVKKSDKASQECEALQERVDSL 1096
                  6788889999999999999999.998888899999999999999887777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1242 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3031  (0.169056); expected 358.6 (0.02)
Passed bias filter:                      610  (0.0340231); expected 358.6 (0.02)
Passed Vit filter:                       248  (0.0138323); expected 17.9 (0.001)
Passed Fwd filter:                       149  (0.00831056); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 5.23u 0.44s 00:00:05.67 Elapsed: 00:00:01.06
# Mc/sec: 3543.00
//
Query:       EEA20787.1  [L=716]
Description: CHY and RING finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.7e-24   85.6   0.3    1.7e-24   85.6   0.3    3.3  3  zinc_ribbon_6   Zinc-ribbon
    7.6e-20   71.2  18.0    7.6e-20   71.2  18.0    3.7  3  zf-CHY          CHY zinc finger
    1.8e-08   34.6   7.2    1.8e-08   34.6   7.2    4.8  6  zf-RING_2       Ring finger domain
    8.8e-06   25.6   6.8    8.8e-06   25.6   6.8    6.0  6  zf-RING_5       zinc-RING finger domain
    2.7e-05   23.9   5.6    2.7e-05   23.9   5.6    4.4  5  zf-C3HC4_2      Zinc finger, C3HC4 type (RING finger)
    9.3e-05   22.3   3.6    9.3e-05   22.3   3.6    5.4  6  Prok-RING_1     Prokaryotic RING finger family 1
    0.00026   21.0   6.8    0.00026   21.0   6.8    2.9  2  zf-RING_UBOX    RING-type zinc-finger


Domain annotation for each model (and alignments):
>> zinc_ribbon_6  Zinc-ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   2.8       6.3   1.6e+04      48      58 ..     324     334 ..     317     343 .. 0.56
   2 ?   -2.6   1.5       2.3   5.8e+03      30      36 ..     397     403 ..     389     406 .. 0.71
   3 !   85.6   0.3   6.5e-28   1.7e-24       1      58 [.     490     547 ..     490     548 .. 0.98

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 6.3
  zinc_ribbon_6  48 lkCkeCgSYNT 58 
                    l+C +C+ + T
     EEA20787.1 324 LQCYTCKKWYT 334
                    44555544333 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 2.3
  zinc_ribbon_6  30 ilCnDCe 36 
                     +C+DC+
     EEA20787.1 397 YHCHDCG 403
                    4699995 PP

  == domain 3  score: 85.6 bits;  conditional E-value: 6.5e-28
  zinc_ribbon_6   1 vdmeayfraldaeiaeqpmpeeyknkkvkilCnDCekksevkfhvlglkCkeCgSYNT 58 
                    +++ea fr+ld++i++qpmp e++++++ i+CnDC++ks+v++h+lglkC+ C+SYNT
     EEA20787.1 490 MNLEARFRNLDRTIESQPMPIEFEDTRAMIYCNDCGAKSNVPYHWLGLKCDLCESYNT 547
                    6899****************************************************** PP

>> zf-CHY  CHY zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.2  18.0     3e-23   7.6e-20       1      75 []     315     388 ..     315     388 .. 0.99
   2 ?   -8.1  23.1         7   1.8e+04       5      73 ..     400     486 ..     391     488 .. 0.69
   3 ?    0.2   8.2      0.42   1.1e+03      14      74 ..     474     544 ..     463     545 .. 0.61

  Alignments for each domain:
  == domain 1  score: 71.2 bits;  conditional E-value: 3e-23
      zf-CHY   1 CkHykravvairapcCkklyaCreCHeeledhelerlevkevlcllCeteqekavlCkkCkkefaeyfCpiCkll 75 
                 C Hykr+ v++++ +Ckk+y+Cr CH+++edh+ler++++++lc+lC   q++a+ Ck C++++a+yfC +Ckl+
  EEA20787.1 315 CLHYKRN-VKLQCYTCKKWYTCRFCHNQSEDHALERQKTENMLCMLCGLPQPAAQWCKGCGERAASYFCAVCKLW 388
                 99*****.****************************************************************985 PP

  == domain 2  score: -8.1 bits;  conditional E-value: 7
      zf-CHY   5 kra.vvairapcCkklyaCreCH.....eeledhelerlevkevlcllCeteq...ekavlCkkCkk..........efaeyfCpiCk 73 
                 +   +++i     k++y+C++C      + +++h++ + +++ + c  C +     + +v+  +C++          + ++y CpiC+
  EEA20787.1 400 HDCgICRIGQGIGKDFYHCKTCSvcipiSIENTHRCIERSTQ-CDCPICGEYMftsPDTVVFMRCGHsihqkcydefSKTSYRCPICS 486
                 444588888899999********9999855677877666655.6688887754222666665556665555555555556679****7 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.42
      zf-CHY  14 pcCkklyaCreCH.....eeledhelerlevkevlcllCeteq.ekavlCkkCkk.efaey.....fCpiCkl 74 
                 +  k+ y C  C       e + ++l+r+ +++ + +  e e+ ++ + C+ C+  +   y     +C+ C++
  EEA20787.1 474 EFSKTSYRCPICSksimnLEARFRNLDRTIESQPMPI--EFEDtRAMIYCNDCGAkSNVPYhwlglKCDLCES 544
                 556789*******555442234456677666655444..4443267889****88333345677778999975 PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   9.0         7   1.8e+04       6      43 ..     315     360 ..     306     361 .. 0.73
   2 ?   -4.6  12.5         7   1.8e+04       3      44 .]     357     406 ..     352     406 .. 0.65
   3 ?   -5.8  15.5         7   1.8e+04       2      43 ..     401     447 ..     400     447 .. 0.46
   4 !   34.6   7.2     7e-12   1.8e-08       2      43 ..     443     485 ..     442     486 .. 0.90
   5 ?   -3.4   1.3       5.2   1.3e+04      25      31 ..     520     526 ..     512     544 .. 0.49
   6 ?   -3.6   0.2       6.1   1.6e+04       2      10 ..     538     545 ..     537     549 .. 0.68

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 7
   zf-RING_2   6 CleelssadsvlllpCgHv.fhreCl....erwlrssst....CPlC 43 
                 Cl  ++++ ++++  C++   +r C     ++ l++++t    C lC
  EEA20787.1 315 CL-HYKRNVKLQCYTCKKWyTCRFCHnqseDHALERQKTenmlCMLC 360
                 54.56666667766899874577777444455588888899999999 PP

  == domain 2  score: -4.6 bits;  conditional E-value: 7
   zf-RING_2   3 CpICleel.ssadsvlllpCgH...v.fhreClerw.lrssst......CPlCr 44 
                 C++C   l ++a ++++  Cg    + f+  C + w + ss++      C +Cr
  EEA20787.1 357 CMLCG--LpQPAAQWCKG-CGEraaSyFCAVC-KLWdNDSSKSiyhchdCGICR 406
                 66673..32444555554.*96677669****.566555555577777799998 PP

  == domain 3  score: -5.8 bits;  conditional E-value: 7
   zf-RING_2   2 eCpICl..eelssadsvlllpCgHvfhreCl.......erwlrssst..CPlC 43 
                 +C+IC   + + ++       C+   +  C+        r +++s +  CP+C
  EEA20787.1 401 DCGICRigQGIGKDFYH----CK--TCSVCIpisientHRCIERSTQcdCPIC 447
                 69999634444443333....32..344455444433222233333356**** PP

  == domain 4  score: 34.6 bits;  conditional E-value: 7e-12
   zf-RING_2   2 eCpIC.leelssadsvlllpCgHvfhreClerwlrssstCPlC 43 
                 +CpIC    ++s+d+v+ + CgH++h++C +++ ++s +CP+C
  EEA20787.1 443 DCPICgEYMFTSPDTVVFMRCGHSIHQKCYDEFSKTSYRCPIC 485
                 7****555669999999999*********************** PP

  == domain 5  score: -3.4 bits;  conditional E-value: 5.2
   zf-RING_2  25 fhreCle 31 
                 ++ +C +
  EEA20787.1 520 YCNDCGA 526
                 4555542 PP

  == domain 6  score: -3.6 bits;  conditional E-value: 6.1
   zf-RING_2   2 eCpICleel 10 
                 +C +C e++
  EEA20787.1 538 KCDLC-ESY 545
                 69999.555 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -8.0   9.7         7   1.8e+04      41      44 .]     328     331 ..     312     362 .. 0.52
   2 ?    0.0   1.1      0.33   8.5e+02      25      43 ..     370     386 ..     367     387 .. 0.90
   3 ?   -2.3   0.6       1.7   4.4e+03      37      43 ..     400     406 ..     392     407 .. 0.71
   4 ?  -11.4  16.7         7   1.8e+04      26      43 ..     433     448 ..     398     449 .. 0.90
   5 !   25.6   6.8   3.4e-09   8.8e-06       2      44 .]     444     487 ..     443     487 .. 0.95
   6 ?   -1.2   0.6      0.81   2.1e+03      23      40 ..     519     540 ..     519     544 .. 0.60

  Alignments for each domain:
  == domain 1  score: -8.0 bits;  conditional E-value: 7
   zf-RING_5  41 iCrk 44 
                 +C+k
  EEA20787.1 328 TCKK 331
                 4433 PP

  == domain 2  score: 0.0 bits;  conditional E-value: 0.33
   zf-RING_5  25 CekClkkllekeavCpiCr 43 
                 C+ C  ++   ++ C +C+
  EEA20787.1 370 CKGCGERAA--SYFCAVCK 386
                 999999999..999****7 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 1.7
   zf-RING_5  37 avCpiCr 43 
                 ++C iCr
  EEA20787.1 400 HDCGICR 406
                 4677775 PP

  == domain 4  score: -11.4 bits;  conditional E-value: 7
   zf-RING_5  26 ekClkkllekeavCpiCr 43 
                 ++C+ +++  + +CpiC+
  EEA20787.1 433 HRCIERST--QCDCPICG 448
                 58999999..999****7 PP

  == domain 5  score: 25.6 bits;  conditional E-value: 3.4e-09
   zf-RING_5   2 CnkCfekl.skeekfyltsCgHifCekClkkllekeavCpiCrk 44 
                 C++C e + ++ + +++++CgH++++kC ++ ++ +++CpiC+k
  EEA20787.1 444 CPICGEYMfTSPDTVVFMRCGHSIHQKCYDEFSKTSYRCPICSK 487
                 ******99999999****************************86 PP

  == domain 6  score: -1.2 bits;  conditional E-value: 0.81
   zf-RING_5  23 ifCekClkkll....ekeavCp 40 
                 i+C++C  k+         +C 
  EEA20787.1 519 IYCNDCGAKSNvpyhWLGLKCD 540
                 6888888777655554444555 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -5.8   2.7         7   1.8e+04      22      28 ..     334     340 ..     325     345 .. 0.59
   2 ?   -2.5   1.1       1.9   4.8e+03      22      40 .]     369     385 ..     368     385 .. 0.64
   3 ?  -15.3  19.1         7   1.8e+04      25      40 .]     434     447 ..     381     447 .. 0.83
   4 !   23.9   5.6     1e-08   2.7e-05       2      40 .]     444     485 ..     443     485 .. 0.77
   5 ?   -1.9   0.1       1.3   3.2e+03      22      30 ..     520     528 ..     519     529 .. 0.84

  Alignments for each domain:
  == domain 1  score: -5.8 bits;  conditional E-value: 7
  zf-C3HC4_2  22 fCqkCil 28 
                 +C+ C  
  EEA20787.1 334 TCRFCHN 340
                 4555555 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 1.9
  zf-C3HC4_2  22 fCqkCilrsLeekneCPlC 40 
                  C+ C  r+  ++  C +C
  EEA20787.1 369 WCKGCGERA--ASYFCAVC 385
                 688888886..44455555 PP

  == domain 3  score: -15.3 bits;  conditional E-value: 7
  zf-C3HC4_2  25 kCilrsLeekneCPlC 40 
                  Ci rs   +  CP+C
  EEA20787.1 434 RCIERS--TQCDCPIC 447
                 577775..45588888 PP

  == domain 4  score: 23.9 bits;  conditional E-value: 1e-08
  zf-C3HC4_2   2 CpiCld.mlkdpsvvt..pCgHvfCqkCilrsLeekneCPlC 40 
                 CpiC + m+  p +v    CgH+ +qkC ++  + + +CP+C
  EEA20787.1 444 CPICGEyMFTSPDTVVfmRCGHSIHQKCYDEFSKTSYRCPIC 485
                 ****88456655444346*************756666***** PP

  == domain 5  score: -1.9 bits;  conditional E-value: 1.3
  zf-C3HC4_2  22 fCqkCilrs 30 
                 +C++C ++s
  EEA20787.1 520 YCNDCGAKS 528
                 7****9885 PP

>> Prok-RING_1  Prokaryotic RING finger family 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   2.6       5.7   1.5e+04       7      28 ..     335     362 ..     327     371 .. 0.57
   2 ?   -5.7   5.3         7   1.8e+04       7      27 ..     382     403 ..     366     406 .. 0.61
   3 ?   -4.8   4.4         7   1.8e+04       6      26 ..     401     421 ..     396     425 .. 0.69
   4 !   22.3   3.6   3.6e-08   9.3e-05       3      39 ..     440     476 ..     438     481 .. 0.92
   5 ?    2.1   0.2      0.07   1.8e+02       2      14 ..     477     489 ..     476     493 .. 0.81
   6 ?    1.6   0.3      0.11   2.8e+02      14      31 ..     512     533 ..     510     539 .. 0.76

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 5.7
  Prok-RING_1   7 CpvCgkelkee......dDiVvCpeCgt 28 
                  C  C+++ ++            C  Cg 
   EEA20787.1 335 CRFCHNQSEDHalerqkTENMLCMLCGL 362
                  6666655444333333334445555555 PP

  == domain 2  score: -5.7 bits;  conditional E-value: 7
  Prok-RING_1   7 CpvCgkelkee.dDiVvCpeCg 27 
                  C vC+   ++  + i  C +Cg
   EEA20787.1 382 CAVCKLWDNDSsKSIYHCHDCG 403
                  6666543332225566677776 PP

  == domain 3  score: -4.8 bits;  conditional E-value: 7
  Prok-RING_1   6 kCpvCgkelkeedDiVvCpeC 26 
                   C +C+     ++D   C +C
   EEA20787.1 401 DCGICRIGQGIGKDFYHCKTC 421
                  677777776677777777777 PP

  == domain 4  score: 22.3 bits;  conditional E-value: 3.6e-08
  Prok-RING_1   3 tgkkCpvCgkelkeedDiVvCpeCgtpyHraCyekag 39 
                  t+  Cp+Cg+ +    D Vv   Cg + H++Cy+++ 
   EEA20787.1 440 TQCDCPICGEYMFTSPDTVVFMRCGHSIHQKCYDEFS 476
                  6789*****************************9875 PP

  == domain 5  score: 2.1 bits;  conditional E-value: 0.07
  Prok-RING_1   2 ytgkkCpvCgkel 14 
                  +t  +Cp+C+k +
   EEA20787.1 477 KTSYRCPICSKSI 489
                  56789*****987 PP

  == domain 6  score: 1.6 bits;  conditional E-value: 0.11
  Prok-RING_1  14 lkeedDiVvCpeCgt....pyH 31 
                  +++   ++ C +Cg+    pyH
   EEA20787.1 512 FEDTRAMIYCNDCGAksnvPYH 533
                  777778899*****84444555 PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.9   1.7         7   1.8e+04      21      25 ..     421     425 ..     421     442 .. 0.49
   2 !   21.0   6.8     1e-07   0.00026       1      39 []     444     483 ..     444     488 .. 0.87

  Alignments for each domain:
  == domain 1  score: -4.9 bits;  conditional E-value: 7
  zf-RING_UBOX  21 CreCl 25 
                   C+ C+
    EEA20787.1 421 CSVCI 425
                   55566 PP

  == domain 2  score: 21.0 bits;  conditional E-value: 1e-07
  zf-RING_UBOX   1 CpICle.lftdP..lv.lpCGHtFCreClwelskslegafkCP 39 
                   CpIC e  ft P  +v + CGH+++++C    ++ ++++++CP
    EEA20787.1 444 CPICGEyMFTSPdtVVfMRCGHSIHQKCY---DEFSKTSYRCP 483
                   *****95667899755568**********...99999999999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (716 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       978  (0.0545485); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.77u 0.30s 00:00:01.07 Elapsed: 00:00:00.53
# Mc/sec: 4096.71
//
Query:       EEA20788.1  [L=889]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.8e-31  106.4   0.2    1.4e-30  105.4   0.2    1.5  1  DUF2293   Uncharacterized conserved protein (DUF2293)


Domain annotation for each model (and alignments):
>> DUF2293  Uncharacterized conserved protein (DUF2293)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  105.4   0.2   7.6e-35   1.4e-30       2      85 .]     157     239 ..     156     239 .. 0.99

  Alignments for each domain:
  == domain 1  score: 105.4 bits;  conditional E-value: 7.6e-35
     DUF2293   2 lrdlfpriPetdaeaiiehafkkgsgrvgrtekiplerrvqlAvlAhiRHthTdYDeLlkegvereeARraveekvldvlvkWr 85 
                 +rdlfpriP++d ++ii++af+kg+++vg++ ++pl+rr+qlAv+AhiRH +TdYD+Llk+ ++ +eARr ve+ +l+ lv+Wr
  EEA20788.1 157 IRDLFPRIPDDDINQIIKTAFQKGQRKVGTAVELPLARRAQLAVVAHIRHLYTDYDKLLKT-TSFQEARRSVEDSTLEKLVQWR 239
                 89***********************************************************.*********************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (889 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       333  (0.0185733); expected 358.6 (0.02)
Passed bias filter:                      258  (0.0143901); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.29s 00:00:00.97 Elapsed: 00:00:00.50
# Mc/sec: 5355.92
//
Query:       EEA20789.1  [L=79]
Description: iron/copper transporter Atx1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      5e-17   62.1   0.9    5.8e-17   61.9   0.9    1.1  1  HMA          Heavy-metal-associated domain
  ------ inclusion threshold ------
      0.059   13.7   0.1       0.15   12.4   0.0    1.7  2  Fer2_BFD     BFD-like [2Fe-2S] binding domain
       0.16   12.0   0.7        2.2    8.2   0.2    2.1  2  GnsAB_toxin  GnsA/GnsB toxin of bacterial toxin-antitoxin sys


Domain annotation for each model (and alignments):
>> HMA  Heavy-metal-associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.9   0.9   9.7e-21   5.8e-17       2      61 ..       8      65 ..       7      66 .. 0.95

  Alignments for each domain:
  == domain 1  score: 61.9 bits;  conditional E-value: 9.7e-21
         HMA  2 vrvsgmhCagCaakvekvLselpgVesvkvdlatktvtVegdaestklrkiieaiekagy 61
                ++v  m C+gC+++ve+vL++l+gV+s++v+l+++t+tV+ +++   ++k++e+i+k+g+
  EEA20789.1  8 FNV-SMSCGGCSGAVERVLKKLDGVKSYDVSLESQTATVVAEDSL-GYEKVLETIKKTGK 65
                778.7************************************9997.88***********8 PP

>> Fer2_BFD  BFD-like [2Fe-2S] binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   2.6e-05      0.15      33      50 ..       9      26 ..       2      27 .. 0.89
   2 ?   -2.0   0.0      0.81   4.9e+03      11      20 ..      54      63 ..      50      69 .. 0.58

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2.6e-05
    Fer2_BFD 33 kagtgCggCrpaieeiLa 50
                ++++ CggC  a+e++L+
  EEA20789.1  9 NVSMSCGGCSGAVERVLK 26
                6899***********997 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.81
    Fer2_BFD 11 geIrdairra 20
                +++ + i++ 
  EEA20789.1 54 EKVLETIKKT 63
                5677777443 PP

>> GnsAB_toxin  GnsA/GnsB toxin of bacterial toxin-antitoxin system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0     0.025   1.5e+02      43      52 ..      27      36 ..      24      38 .. 0.87
   2 ?    8.2   0.2   0.00037       2.2      20      35 ..      54      69 ..      39      72 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.025
                 ETTEEEEEEE CS
  GnsAB_toxin 43 kmtGLEsYdV 52
                 k+ G+ sYdV
   EEA20789.1 27 KLDGVKSYDV 36
                 789******9 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.00037
                 HHHHHHHHHHSSEEEE CS
  GnsAB_toxin 20 kKiaELkKkTGkEVse 35
                  K+ E  KkTGk V +
   EEA20789.1 54 EKVLETIKKTGKTVNS 69
                 69**********9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (79 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       665  (0.0370907); expected 358.6 (0.02)
Passed bias filter:                      520  (0.0290033); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.48
# Mc/sec: 491.69
//
Query:       EEA20790.1  [L=969]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.1e-205  684.9   0.6   2.4e-205  684.7   0.6    1.0  1  Rrn6      RNA polymerase I-specific transcription-initiation 


Domain annotation for each model (and alignments):
>> Rrn6  RNA polymerase I-specific transcription-initiation factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  684.7   0.6  1.4e-209  2.4e-205       1     851 []     101     969 .]     101     969 .] 0.89

  Alignments for each domain:
  == domain 1  score: 684.7 bits;  conditional E-value: 1.4e-209
        Rrn6   1 DPtvgsLlaigeiqdvsddrsksr....vpilAyasGesgsiLrLarleeekwewgedksvtlrvptidesesgewisdgapIkqIkfaqsserfeeks 95 
                 +P+++s+l +g++q ++++r +++    vpi+A+asG+++++L+L+ +e e++  + ++++ +rvpti+ s+ ++wi++++pI+qIkfa+s e   +  
  EEA20790.1 101 NPQISSVLGFGNAQLSEQVRIRRGrmrtVPIAAFASGQNQNVLSLRLIEAERVVTNLEQDAAFRVPTIGCSRAVDWICNETPIRQIKFADSIE---NPG 196
                 7*****************999888888******************************************************************...999 PP

        Rrn6  96 twlaVrtetsttifrplyhrvpvperspe...ssidskspsridanplleisssetggfphaDvaFNPwdqrqfAivDekGnWsvwdisg..rkrknks 189
                 ++laVr+ +st if+p+yhr+++++++pe      ++ + s+id+++++ei++s+tggf+h+Dv+FNPw+ +qfAivDe+G+Ws+w++++  r ++   
  EEA20790.1 197 DLLAVRLLSSTAIFQPVYHREAQLIDPPElsgLAYSRPQVSHIDPCLVAEIDVSQTGGFTHVDVTFNPWYLKQFAIVDERGHWSIWQLQNivRLDN--- 292
                 ******************************9999999999*************************************************9755554... PP

        Rrn6 190 klsaslrksgsifdpeledlsset....eldgwkrIlWvsdvntLlVcnrrklvlvdikgnsqeelvlaltlsrssewILDvkrspvnpshvfvLTste 284
                  ++++l +s  ++++  +d+ ++     ++d+w r +Wv dvnt++Vc rr+++l+ ++g+++ ++ ++l++++s+ewILDvk+++++ s +f+LT+t+
  EEA20790.1 293 GVAPELLHSDFLPCDAADDKGESLtdevKYDTWGRLEWVRDVNTFIVCGRRNAMLYVLEGTTATSYRIELNWQSSTEWILDVKTCSSQNSLGFILTTTR 391
                 89***********9998888877689************************************************************************* PP

        Rrn6 285 liwldvtssseasasdeqaeltrllSwkHfrdpeDttLrltvlevgkgsedllvliySrlnnlvlvfrfsisssessaqssgsDPfildlpq.....ds 378
                 ++++d+     + a++e++++++++ w H+rd++D tLrlt+l+++   e++++l+ySrl +++lvf+++++  e  ++s +sDPf++++p+     + 
  EEA20790.1 392 ILCFDF-----KLADQETQPIRPQFAWLHDRDADDLTLRLTSLTIA---EEYYLLLYSRLDSCILVFQVPVDGYEDGIYS-MSDPFFIYVPSrpnanGL 481
                 *****8.....56789******************************...9***********************9976666.669*********999999 PP

        Rrn6 379 eteeassgissiqvlpaflfrseedssglgrdyseegvkffqlfvldsdlslheslys..sstepsrelrspakelrlkdlskssikrkkkekrkktas 475
                 +t + +s i++i v++      e++   ++r + e++++f++lf++d ++++he+lys  s  ++ +el+++++ l l+ +s  s k+k+k+ r++t++
  EEA20790.1 482 NTIRYESPIKQILVKE-----VEQQIYLSNRVTLEHCPRFIKLFMVDGTMAIHEYLYSkpSGLSSADELKVGREALLLSAVSLLSNKKKRKGDRETTVE 575
                 9999999*****9987.....799***********************************9999999********************************* PP

        Rrn6 476 rkeddfvvpdglelkvrkeksaklkrsssaslapeqrtldfervy...........sassteeaeeqsfqdllyrlseaiqqlllegsesersplktll 563
                  +++d v++   +          l++s+ ++++p+++++df+++y           ++ s++  e qsf+d++++l +a+ + ++eg++ ++    t+l
  EEA20790.1 576 PSDNDDVDDINRM---------PLYLSKPIETRPARVSVDFTKIYsllsrgdsqhlVRPSVSLPEYQSFRDYVEHLIIAVTNSAEEGHSFVH----TML 661
                 *****88888777.........9*********************************************************************....*** PP

        Rrn6 564 eladlplsvedvdefaseleqllsfyeekditfsslktilklllselvs.r..............slddiydkllelWlsplprdipsrvrlakerlir 647
                 ++ d+p+ + d+d+ ++el+++ s        ++s++t l  l  + ++ r              ++  +y+kl+++Wl +lpr++ps++r++ke+lir
  EEA20790.1 662 DIIDNPPVLFDIDDSSHELDWFRS---RFLPMEPSAETALCFLPLNVSPeRsheqanvirsfqpfGVLILYEKLVRDWLFKLPRNLPSWIRISKEKLIR 757
                 ************************...3333333333333333333333515567778889999*********************************** PP

        Rrn6 648 evaaelllSsirvsklraeasslssslssss......ssssssssssssedpelsr..edplda.lsrytklikssptslsrsvsniLshWelgsdpae 737
                 +v +el+l+ +    + + + + s s  ss+       ss+ s+++s +  +  s+  +++++a l   t + +s++  l++ +++iLs W++g dp+ 
  EEA20790.1 758 QVSIELSLAGTV---QIDIPIPDSVSIVSSQpslpgrRSSTVSQRDSVNGVADFSKehNMVTHAlLDLKTVSPPSMSILLGGATQDILSLWNVGGDPDF 853
                 ***********9...45566666666666666677743344444444444455555899**************************************** PP

        Rrn6 738 ydwqrtesaleaeeq.rqrarrkrekrrrrkeklklasraeasssssssqssssksssssssqlpsssqvptlpdfslsmqissSQvvsss.mSQperG 834
                 +d +r+ +a+  e +  +r+r+++++r r +++ +    + as +s +s+++  +   s s++ + s+ +p+ ++      ++sSQ+++s  m+Q erG
  EEA20790.1 854 FDLERALEAETGERDfGSRSRSRSAQRTRTRSRSR---ANSASGRSIRSSPVVPSMKFSGSQPQFDSARLPIRSS----QFLPSSQITDSMpMTQAERG 945
                 **********9766686667777777777777722...3333333333333343444455555555555555555....345677776655******** PP

        Rrn6 835 rFgsRpak.......kKKKRkaGF 851
                 +FgsR+a+       +KKKR+aGF
  EEA20790.1 946 VFGSRQAGkksnvkaRKKKRAAGF 969
                 ******99**************** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (969 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       440  (0.0245412); expected 358.6 (0.02)
Passed bias filter:                      367  (0.0204696); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.74u 0.28s 00:00:01.02 Elapsed: 00:00:00.44
# Mc/sec: 6553.03
//
Query:       EEA20791.1  [L=257]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.9e-21   74.5   0.0    1.8e-20   72.9   0.0    1.9  1  Spindle_Spc25    Chromosome segregation protein Spc25
     0.0018   18.0   9.4     0.0035   17.0   9.4    1.5  1  Filament         Intermediate filament protein
  ------ inclusion threshold ------
      0.032   14.1   0.9      0.057   13.3   0.9    1.4  1  Polysacc_deac_1  Polysaccharide deacetylase
       0.12   11.7   7.7       0.21   10.9   7.7    1.3  1  DUF4407          Domain of unknown function (DUF4407)
       0.17   12.2   1.7        0.3   11.3   0.2    2.1  2  RILP             Rab interacting lysosomal protein
        1.4    8.0   9.2        2.1    7.3   9.2    1.2  1  Atg14            Vacuolar sorting 38 and autophagy-related su
        3.9    7.6  14.3        1.1    9.4  10.8    1.9  2  BRE1             BRE1 E3 ubiquitin ligase


Domain annotation for each model (and alignments):
>> Spindle_Spc25  Chromosome segregation protein Spc25
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.9   0.0     7e-24   1.8e-20       2      72 ..     182     252 ..     181     253 .. 0.98

  Alignments for each domain:
  == domain 1  score: 72.9 bits;  conditional E-value: 7e-24
  Spindle_Spc25   2 ieedklkfvFtnidpkdperefsftLdvsedtyevlecsPkLedeeleelleeLnetndlgkFlkevRkaF 72 
                    ++ed+lk+v+t++ +kd+e+e++f+L + +++ye+ +++PkLe+e +++ l+ +ne++d+g++lk++R++F
     EEA20791.1 182 GREDRLKIVYTHLLEKDWEKEAWFELGTASRDYEIYHTKPKLEREAIQRELDIVNEDRDFGALLKRMRRLF 252
                    689*******************************************************************9 PP

>> Filament  Intermediate filament protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   9.4   1.4e-06    0.0035     171     271 ..      62     160 ..      35     168 .. 0.78

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 1.4e-06
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXX-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Filament 171 lkeiraqyeelaeknreeaeewyksklee...lqeaaeknsealrsakeeitelrrqiqsleieleslkkqkasleaqlaeleerleaeleklqeklse 266
                 l+e r+    + ++n +e+++ y  k ++   l+++ + +++++++   e +e++ +i s + e ++  ++++ l++q+ae+++ ++++l+  ++  + 
  EEA20791.1  62 LQE-RN----QFHSNLAELQKDYDMKHNDikiLTSKTQDHQQTIQREGAEAAEIHAHISSITLERDNRLSKRDRLKRQIAETQNAIDQKLQAQKAHSQY 155
                 444.34....445667777777777766611156788889999999999***************************************99999998888 PP

                 HHHHH CS
    Filament 267 leeel 271
                 l+++ 
  EEA20791.1 156 LDSQA 160
                 88775 PP

>> Polysacc_deac_1  Polysaccharide deacetylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.9   2.2e-05     0.057      39      97 ..      88     149 ..      48     160 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 2.2e-05
                      E-HHHHCH-HHHHHHHHHTTEEEEE-..-SS--EGGGSHHH.HHHHHHHHHHHHHHHHHS-- CS
  Polysacc_deac_1  39 vigglvedypdevremaasGveignH..tinhsnlkrlsee.evrreierakdalrkalgre 97 
                      +++++++d+++ +++  a+  ei++H  +i+ ++ +rls++ +++r+i++++ a+ ++l+ +
       EEA20791.1  88 ILTSKTQDHQQTIQREGAEAAEIHAHisSITLERDNRLSKRdRLKRQIAETQNAIDQKLQAQ 149
                      678999********************6668888999999998***************99875 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   7.7     8e-05      0.21     124     225 ..      47     159 ..      35     171 .. 0.61

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 8e-05
     DUF4407 124 keqlaaaltaelaeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaake..............kkaqldaaqaelaelkaklda 208
                 +++ +a  ++  ++  +++++  ++++++++++d + ++ +  ++ t+  + + ++++g++a e              + ++ d++++++ae ++    
  EEA20791.1  47 TAKFDAFIEKGRKQVLQERNQFHSNLAELQKDYDMKHNDIKILTSKTQDHQ-QTIQREGAEAAEihahissitlerdnRLSKRDRLKRQIAETQNA--I 142
                 444444455555666666667777777777777777777765555554333.33788899999966666666666666666666666666666666..5 PP

     DUF4407 209 tarlaalraelaeleae 225
                 +++l+a++a  + l+++
  EEA20791.1 143 DQKLQAQKAHSQYLDSQ 159
                 55555555555555444 PP

>> RILP  Rab interacting lysosomal protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.2   0.00012       0.3       6      23 ..      59      76 ..      59      81 .. 0.94
   2 ?   -1.7   0.1       1.4   3.5e+03      11      23 ..     127     139 ..     125     154 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00012
        RILP  6 rdVLqERNeLKaqlfllq 23
                ++VLqERN+  ++l +lq
  EEA20791.1 59 KQVLQERNQFHSNLAELQ 76
                79************9999 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 1.4
        RILP  11 ERNeLKaqlfllq 23 
                  R  LK q+ + q
  EEA20791.1 127 KRDRLKRQIAETQ 139
                 5777887776655 PP

>> Atg14  Vacuolar sorting 38 and autophagy-related subunit 14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   9.2   0.00082       2.1      24     139 ..      36     149 ..      25     167 .. 0.73

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.00082
       Atg14  24 lyelrerlaklksekeslkkkiekalegkeeaeqledkiknkkakleelksliadlrerlqelkdklsqlkkeieekkkklaklsdklkkRrsdleslq 122
                 +++lr r+a++ ++ +++ +k  k + +++  +q  +++  ++++ + + ++i +l +++q  ++++++  +e +e  +++++   +   R s+ + l+
  EEA20791.1  36 FEDLRSRMAQFTAKFDAFIEKGRKQVLQER--NQFHSNLAELQKDYDMKHNDIKILTSKTQDHQQTIQREGAEAAEIHAHISSITLERDNRLSKRDRLK 132
                 455555555555555555555555555555..8999999999999999999999999999999999999999999999999988888887888877778 PP

       Atg14 123 neleerrkkqiaklqda 139
                  +++e ++++ +klq +
  EEA20791.1 133 RQIAETQNAIDQKLQAQ 149
                 88888777777777733 PP

>> BRE1  BRE1 E3 ubiquitin ligase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4  10.8   0.00042       1.1       4      90 ..      71     157 ..      68     161 .. 0.94
   2 ?   -3.0   0.0       3.1   7.9e+03      32      53 ..     226     247 ..     220     253 .. 0.51

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00042
        BRE1   4 ELvklekafeelseqlskkvkeltileekklrleaekakadqkyfaamrskdalenelkkLnkllsKsselieqLkelekefvrklk 90 
                  L +l+k ++  ++ ++ ++++++++++ ++r  ae a+ +  + ++  ++d++  +  +L+++++  +  i+q  +++k+  + l+
  EEA20791.1  71 NLAELQKDYDMKHNDIKILTSKTQDHQQTIQREGAEAAEIHAHISSITLERDNRLSKRDRLKRQIAETQNAIDQKLQAQKAHSQYLD 157
                 68899************************************************************************9999988886 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 3.1
        BRE1  32 kklrleaekakadqkyfaamrs 53 
                 + ++ e ++  +d+ + a+ + 
  EEA20791.1 226 EAIQRELDIVNEDRDFGALLKR 247
                 4444444555555555554444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (257 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1860  (0.103743); expected 358.6 (0.02)
Passed bias filter:                      639  (0.0356406); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 1734.84
//
Query:       EEA20792.1  [L=309]
Description: meiotic recombination protein Ski8/Rec14, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.9e-20   72.8   9.3    3.6e-07   30.8   0.5    6.0  7  WD40           WD domain, G-beta repeat
    3.4e-16   59.3   0.5     0.0051   17.1   0.0    4.4  4  ANAPC4_WD40    Anaphase-promoting complex subunit 4 WD40 doma
    6.4e-06   26.2   0.1     0.0046   16.9   0.0    2.5  2  eIF2A          Eukaryotic translation initiation factor eIF2A
     0.0002   20.8   0.0       0.16   11.2   0.0    2.2  2  WD40_like      WD40-like domain
    0.00034   19.4   0.1      0.039   12.6   0.1    2.2  2  Nup160         Nucleoporin Nup120/160
     0.0006   18.5   0.1      0.079   11.5   0.0    2.0  2  Cytochrom_D1   Cytochrome D1 heme domain
     0.0064   15.6   0.0      0.051   12.6   0.0    2.1  2  VID27          VID27 C-terminal WD40-like domain
  ------ inclusion threshold ------
      0.035   13.2   0.0      0.047   12.7   0.0    1.2  1  Coatomer_WDAD  Coatomer WD associated region
       0.15   12.0   0.0        4.1    7.4   0.0    2.6  3  Asp_decarbox   Aspartate decarboxylase


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.1       6.3   1.3e+04      10      28 ..      15      34 ..      13      37 .. 0.61
   2 ?    0.1   0.0       0.9   1.8e+03      14      38 .]      63      87 ..      52      87 .. 0.62
   3 !   14.3   0.1   2.9e-05     0.059      14      38 .]     109     133 ..     104     133 .. 0.86
   4 !   11.6   0.0    0.0002       0.4      15      37 ..     152     174 ..     143     175 .. 0.92
   5 !   15.5   0.0   1.2e-05     0.025      11      38 .]     190     217 ..     180     217 .. 0.81
   6 !   30.8   0.5   1.8e-10   3.6e-07       2      38 .]     222     259 ..     221     259 .. 0.91
   7 ?   -1.0   0.0         2   3.9e+03       4      24 ..     266     281 ..     263     303 .. 0.54

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 6.3
                SSS..EEEEEEETTSSEEEEE CS
        WD40 10 Hss..vtslafspdgawlasG 28
                H +  + sla+ +++   asG
  EEA20792.1 15 H-PidIFSLAVTSNQIISASG 34
                5.3337788776666665555 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.9
                EEEEEETTSSEEEE.EETTSEEEEEE CS
        WD40 14 tslafspdgawlas.GsdDgtvriWd 38
                +++ +s++g   as G   g  +iW+
  EEA20792.1 63 HHVVTSRNGLKAASiGF-GGEFKIWN 87
                45555666666442255.89999998 PP

  == domain 3  score: 14.3 bits;  conditional E-value: 2.9e-05
                 EEEEEETTSSEEEEE.ETTSEEEEEE CS
        WD40  14 tslafspdgawlasG.sdDgtvriWd 38 
                 ++++ s dg++la G + +g++++Wd
  EEA20792.1 109 WAICLSEDGRYLA-GtTNNGHIKVWD 133
                 56788******97.7457*******9 PP

  == domain 4  score: 11.6 bits;  conditional E-value: 0.0002
                 EEEEETTSSEEEEEETTSEEEEE CS
        WD40  15 slafspdgawlasGsdDgtvriW 37 
                 +++ s dg+++asG+ +g+++++
  EEA20792.1 152 CIDMSNDGKYIASGHQNGSIYMF 174
                 8999****************976 PP

  == domain 5  score: 15.5 bits;  conditional E-value: 1.2e-05
                 SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  11 ssvtslafspdgawlasGsdDgtvriWd 38 
                 ++v+++afsp g++la+++d + + ++d
  EEA20792.1 190 KPVRAVAFSPGGKLLAAAGDSKVIVLYD 217
                 689*************999677777666 PP

  == domain 6  score: 30.8 bits;  conditional E-value: 1.8e-10
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 ++++ ltGH  ++ sl++s+ g +l+s+s Dg+v++W+
  EEA20792.1 222 EQVTQLTGHsAWILSLDWSHTGEYLLSASFDGKVKVWS 259
                 678889***666****************99*******5 PP

  == domain 7  score: -1.0 bits;  conditional E-value: 2
                 EEEEESS.SSEEEEEEETTSSE CS
        WD40   4 lrtltGH.ssvtslafspdgaw 24 
                 + t +   + v+s       +w
  EEA20792.1 266 VATHSENdKAVWSA------KW 281
                 45444444448988......66 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.0    0.0002       0.4      43      79 ..     110     146 ..      84     155 .. 0.86
   2 !   10.4   0.0   0.00032      0.63      45      74 ..     154     183 ..     150     188 .. 0.87
   3 !   17.1   0.0   2.5e-06    0.0051      39      80 ..     190     231 ..     183     235 .. 0.91
   4 !   16.5   0.4   3.8e-06    0.0075      40      89 ..     233     281 ..     228     284 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.0002
  ANAPC4_WD40  43 sLaWkpdgklLavaysdgevrlldaesgkvvhslsvk 79 
                  +++ ++dg+ La  +++g++++ d ++g+  + +++k
   EEA20792.1 110 AICLSEDGRYLAGTTNNGHIKVWDLSNGEQFRDYETK 146
                  678899***********************98888765 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00032
  ANAPC4_WD40  45 aWkpdgklLavaysdgevrlldaesgkvvh 74 
                    ++dgk +a ++++g++ +++ e+g++  
   EEA20792.1 154 DMSNDGKYIASGHQNGSIYMFSNETGRMPF 183
                  5689**********************9865 PP

  == domain 3  score: 17.1 bits;  conditional E-value: 2.5e-06
  ANAPC4_WD40  39 sevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvks 80 
                  + vr++a++p gklLa a +   + l+d esg+ v +l+ +s
   EEA20792.1 190 KPVRAVAFSPGGKLLAAAGDSKVIVLYDTESGEQVTQLTGHS 231
                  579*********************************998765 PP

  == domain 4  score: 16.5 bits;  conditional E-value: 3.8e-06
  ANAPC4_WD40  40 evrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                   + sL W++ g+ L  a  dg+v++ ++e   +v + s +++ av + +W
   EEA20792.1 233 WILSLDWSHTGEYLLSASFDGKVKVWSVERRACVATHSENDK-AVWSAKW 281
                  5889******************************99877766.5888777 PP

>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.9   0.1    0.0013       2.6     101     159 ..     106     163 ..      82     165 .. 0.79
   2 !   16.9   0.0   2.3e-06    0.0046      76     169 ..     162     257 ..     161     270 .. 0.79

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0013
                 ES--EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE-TT-..-EEEE-TTSSEEE CS
       eIF2A 101 qkrNtiffspkgklvllaGfgnlaGeleiwdvkkkkkiakaeaana..tlvewspdgryvl 159
                     +i  s+ g++  laG  n  G++++wd ++ ++   +e + a    ++ s+dg+y++
  EEA20792.1 106 PDTWAICLSEDGRY--LAGTTNN-GHIKVWDLSNGEQFRDYETKGAfgACIDMSNDGKYIA 163
                 55556777777776..5888885.**************99988766326799******986 PP

  == domain 2  score: 16.9 bits;  conditional E-value: 2.3e-06
                 EEESSSSCEEEEEECS.CEEEEEEE..EES--EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE..-TT--EEEE-TTSSEEEEEE-TTT-SS CS
       eIF2A  76 viyGkmpakvslfdlk.vkviskle..eqkrNtiffspkgklvllaGfgnlaGeleiwdvkkkkkiakae..aanatlvewspdgryvlTattaprlrv 169
                 +  G+++ ++++f+++ +++ ++l+   ++  ++ fsp gkl++ aG   +   + ++d+++ ++++++   +a+  +++ws +g+y+l a+   +++v
  EEA20792.1 162 IASGHQNGSIYMFSNEtGRMPFSLSglIKPVRAVAFSPGGKLLAAAGDSKV---IVLYDTESGEQVTQLTghSAWILSLDWSHTGEYLLSASFDGKVKV 257
                 567888889999988545555555522588899**************9999...999****999999886115566789**********9987766655 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.0   8.2e-05      0.16      50     110 ..     112     177 ..      73     185 .. 0.76
   2 !    7.5   0.0    0.0011       2.2       3      80 ..     192     270 ..     190     280 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 8.2e-05
   WD40_like  50 llddd.lilv.vtlDGtillslleneeevenekieedi.stvkvidd..klliGtnkGsiyvfskd 110
                  l++d  +l  +t+ G i   +l+n+e+ +  + + +  +++++ +d   ++ G ++Gsiy+fs++
  EEA20792.1 112 CLSEDgRYLAgTTNNGHIKVWDLSNGEQFRDYETKGAFgACIDMSNDgkYIASGHQNGSIYMFSNE 177
                 566665666615789************9999999999834667666511566699*********98 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0011
   WD40_like   3 iYsidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvklld.ddlilvvtlDGtillslleneeevenek 80 
                 + ++ +s+ g+l++  g+++ + ++++es+e+v+ +++ +  ++     + ++ +l ++ DG++    +e    v +++
  EEA20792.1 192 VRAVAFSPGGKLLAAAGDSKVIVLYDTESGEQVTQLTGHSAWILSLDWSHtGEYLLSASFDGKVKVWSVERRACVATHS 270
                 6789999*********************************999998876515688999*****9887777777666555 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.6   0.0    0.0054        11     227     258 ..     114     145 ..      90     181 .. 0.76
   2 !   12.6   0.1   1.9e-05     0.039     227     257 ..     241     270 ..     217     294 .. 0.82

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.0054
                 ..TTTEEEEEETT-EEEEEETTTTEEEEEEE- CS
      Nup160 227 eigqtylfalsrdgkLrvWnlltgkclatidl 258
                 +++  yl+  + +g ++vW+l++g + +  ++
  EEA20792.1 114 SEDGRYLAGTTNNGHIKVWDLSNGEQFRDYET 145
                 447789999999***********998776555 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 1.9e-05
                 ..TTTEEEEEETT-EEEEEETTTTEEEEEEE CS
      Nup160 227 eigqtylfalsrdgkLrvWnlltgkclatid 257
                 + +  yl+++s dgk++vW+++   c+at +
  EEA20792.1 241 H-TGEYLLSASFDGKVKVWSVERRACVATHS 270
                 4.5689**********************944 PP

>> Cytochrom_D1  Cytochrome D1 heme domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.5   0.0     4e-05     0.079      43      95 ..     113     166 ..     108     181 .. 0.83
   2 !    4.9   0.0     0.004       7.9      15      65 ..     211     261 ..     202     275 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 4e-05
                   -TT.SSEEEEEETTSEEEEEESSSSSEEEEE.E-SSEEEEEEE--TTSEEEEEE CS
  Cytochrom_D1  43 fasdgRyvyvigRDgkvtliDLwakeivaev.kiGlnarsvavSqddryvivgn 95 
                    ++dgRy+   +  g++++ DL + e  ++    G     +++S+d++y++ g 
    EEA20792.1 113 LSEDGRYLAGTTNNGHIKVWDLSNGEQFRDYeTKGAFGACIDMSNDGKYIASGH 166
                   689*********************9955554156999999**********9985 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.004
                   TEEEEEETTT-SEEEEEE-STTEEEEEE-TT.SSEEEEEETTSEEEEEESS CS
  Cytochrom_D1  15 gkvalldgdskeilavletgyalHisrvfasdgRyvyvigRDgkvtliDLw 65 
                     + l d +s e++ +l ++ a   s   +  g y++ ++ Dgkv++  + 
    EEA20792.1 211 KVIVLYDTESGEQVTQLTGHSAWILSLDWSHTGEYLLSASFDGKVKVWSVE 261
                   335566888888888888888888888888888888888888888876554 PP

>> VID27  VID27 C-terminal WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0      0.15     3e+02     193     209 ..     110     126 ..      97     137 .. 0.76
   2 !   12.6   0.0   2.6e-05     0.051     139     221 ..     138     223 ..     129     246 .. 0.83

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.15
       VID27 193 gldvsadGrwvlatckt 209
                  ++ s+dGr++ +t+++
  EEA20792.1 110 AICLSEDGRYLAGTTNN 126
                 58889999999999875 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 2.6e-05
       VID27 139 selkqyaskndfsava.ttekG.yiavasekGdirlfdrlginaktalPalgdpiigldvsadGrwvlatckty.llLiDalikeg 221
                 +++++y +k  f a     ++G yia + + G i +f +   +   +l  l +p++ +  s  G+ + a+ ++  ++L D++  e 
  EEA20792.1 138 EQFRDYETKGAFGACIdMSNDGkYIASGHQNGSIYMFSNETGRMPFSLSGLIKPVRAVAFSPGGKLLAAAGDSKvIVLYDTESGEQ 223
                 6899********986514445548******************************************99998765167889887654 PP

>> Coatomer_WDAD  Coatomer WD associated region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   2.4e-05     0.047      79     169 ..     156     257 ..      98     284 .. 0.66

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.4e-05
                    XXX...XXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXX......XXXXXXXXXX..XXXXXXXXXXXXXXXXXXX..XXXXXXXXXXXXXXXX CS
  Coatomer_WDAD  79 snr...favlessksvkifknfkekktksikleyqvdkifg......GalLgvkseg.svsfYDweqgklvrridvkk..vknVvwsddgelvalv 162
                    sn+   +a   +++s+  f n +++    ++l+  ++ + +      G lL +  ++ ++++YD e+g++v +++ ++  +    ws +ge++  +
     EEA20792.1 156 SNDgkyIASGHQNGSIYMFSNETGRM--PFSLSGLIKPVRAvafspgGKLLAAAGDSkVIVLYDTESGEQVTQLTGHSawILSLDWSHTGEYLLSA 249
                    44433344444566666666666665..5555444444443445789****9998876999*************96644899999******98776 PP

                    X.XXXXXX CS
  Coatomer_WDAD 163 s.kdtvyi 169
                    s + +v +
     EEA20792.1 250 SfDGKVKV 257
                    42334444 PP

>> Asp_decarbox  Aspartate decarboxylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0      0.15     3e+02      33      54 ..      72      93 ..      65     113 .. 0.82
   2 ?    7.4   0.0    0.0021       4.1      35      64 ..     120     149 ..     109     160 .. 0.83
   3 ?   -3.4   0.0       4.7   9.3e+03      80      98 ..     206     224 ..     203     234 .. 0.64

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.15
                  HHHCT--TTBEEEEEETTT--E CS
  Asp_decarbox 33 leaagileyekvqvvnvnngeR 54
                  l+aa i  + + +++n+nng+ 
    EEA20792.1 72 LKAASIGFGGEFKIWNNNNGDW 93
                  788999999999*******975 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0021
                   HCT--TTBEEEEEETTT--EEEEEEEEEST CS
  Asp_decarbox  35 aagileyekvqvvnvnngeRletYvikger 64 
                    ag +++ +++v++++nge ++ Y  kg  
    EEA20792.1 120 LAGTTNNGHIKVWDLSNGEQFRDYETKGAF 149
                   67888999****************998865 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 4.7
                   -TT-EEEEEEEEEEEHHHH CS
  Asp_decarbox  80 qvgdkviiiayaqleeeea 98 
                   + gd  +i+ y + + e++
    EEA20792.1 206 AAGDSKVIVLYDTESGEQV 224
                   5677777777766555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       388  (0.0216409); expected 358.6 (0.02)
Passed bias filter:                      346  (0.0192983); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.58u 0.31s 00:00:00.88 Elapsed: 00:00:00.50
# Mc/sec: 1865.26
//
Query:       EEA20793.1  [L=222]
Description: meiotic recombination protein Ski8/Rec14, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.2e-22   78.0   4.1    2.2e-07   31.5   0.5    4.9  5  WD40           WD domain, G-beta repeat
    7.8e-17   61.4   0.5    0.00012   22.3   0.0    4.1  4  ANAPC4_WD40    Anaphase-promoting complex subunit 4 WD40 doma
    3.3e-06   27.1   0.0     0.0025   17.7   0.0    2.4  3  eIF2A          Eukaryotic translation initiation factor eIF2A
    0.00012   21.6   0.0       0.17   11.2   0.0    2.1  2  WD40_like      WD40-like domain
    0.00017   20.4   0.1      0.025   13.2   0.1    2.1  2  Nup160         Nucleoporin Nup120/160
    0.00021   20.0   0.0      0.043   12.3   0.0    2.0  2  Cytochrom_D1   Cytochrome D1 heme domain
     0.0039   16.3   0.0      0.026   13.6   0.0    2.0  2  VID27          VID27 C-terminal WD40-like domain
  ------ inclusion threshold ------
      0.018   14.1   0.0      0.022   13.8   0.0    1.2  1  Coatomer_WDAD  Coatomer WD associated region
      0.051   13.3   0.1       0.13   12.0   0.2    1.6  2  Gmad1          Lipoprotein LpqB beta-propeller domain
       0.17   11.6   1.5        9.6    5.9   0.0    2.3  3  Hira           TUP1-like enhancer of split


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.1     2e-05     0.037      14      38 .]      22      46 ..      16      46 .. 0.87
   2 !   12.3   0.0   0.00014      0.25      15      37 ..      65      87 ..      55      88 .. 0.91
   3 !   16.1   0.0   8.6e-06     0.015      11      38 .]     103     130 ..      93     130 .. 0.81
   4 !   31.5   0.5   1.2e-10   2.2e-07       2      38 .]     135     172 ..     134     172 .. 0.91
   5 ?   -0.1   0.0       1.1   2.1e+03       4      26 ..     179     205 ..     176     217 .. 0.53

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 2e-05
                EEEEEETTSSEEEEE.ETTSEEEEEE CS
        WD40 14 tslafspdgawlasG.sdDgtvriWd 38
                ++++ s dg++la G + +g++++Wd
  EEA20793.1 22 WAICLSEDGRYLA-GtTNNGHIKVWD 46
                57788******97.7457*******9 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 0.00014
                EEEEETTSSEEEEEETTSEEEEE CS
        WD40 15 slafspdgawlasGsdDgtvriW 37
                +++ s dg+++asG+ +g+++++
  EEA20793.1 65 CIDMSNDGKYIASGHQNGSIYMF 87
                8999****************986 PP

  == domain 3  score: 16.1 bits;  conditional E-value: 8.6e-06
                 SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  11 ssvtslafspdgawlasGsdDgtvriWd 38 
                 ++v+++afsp g++la+++d + + ++d
  EEA20793.1 103 KPVRAVAFSPGGKLLAAAGDSKVIVLYD 130
                 689*************999677777666 PP

  == domain 4  score: 31.5 bits;  conditional E-value: 1.2e-10
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 ++++ ltGH  ++ sl++s+ g +l+s+s Dg+v++W+
  EEA20793.1 135 EQVTQLTGHsAWILSLDWSHTGEYLLSASFDGKVKVWS 172
                 678899***666****************99*******5 PP

  == domain 5  score: -0.1 bits;  conditional E-value: 1.1
                 EEEEESS.SSEEEEEEETTSSE.........EE CS
        WD40   4 lrtltGH.ssvtslafspdgaw.........la 26 
                 + t +   + v+s       +w         +a
  EEA20793.1 179 VATHSENdKAVWSA------KWlpkigrtegFA 205
                 45444444449998......6655544455544 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.5   0.0   0.00016      0.28      43      79 ..      23      59 ..       8      68 .. 0.87
   2 !   11.1   0.0   0.00021      0.37      44      74 ..      66      96 ..      60     102 .. 0.88
   3 !   22.3   0.0   6.5e-08   0.00012      39      90 ..     103     153 ..      96     153 .. 0.94
   4 !   17.2   0.5   2.5e-06    0.0046      40      89 ..     146     194 ..     141     197 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00016
  ANAPC4_WD40 43 sLaWkpdgklLavaysdgevrlldaesgkvvhslsvk 79
                 +++ ++dg+ La  +++g++++ d ++g+  + +++k
   EEA20793.1 23 AICLSEDGRYLAGTTNNGHIKVWDLSNGEQFRDYETK 59
                 578899***********************98888765 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00021
  ANAPC4_WD40 44 LaWkpdgklLavaysdgevrlldaesgkvvh 74
                 +  ++dgk +a ++++g++ +++ e+g++  
   EEA20793.1 66 IDMSNDGKYIASGHQNGSIYMFSNETGRMPF 96
                 56689**********************9865 PP

  == domain 3  score: 22.3 bits;  conditional E-value: 6.5e-08
  ANAPC4_WD40  39 sevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgWg 90 
                  + vr++a++p gklLa a +   + l+d esg+ v +l+ +s   + +l+W+
   EEA20793.1 103 KPVRAVAFSPGGKLLAAAGDSKVIVLYDTESGEQVTQLTGHSA-WILSLDWS 153
                  579***********************************99999.6***9995 PP

  == domain 4  score: 17.2 bits;  conditional E-value: 2.5e-06
  ANAPC4_WD40  40 evrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                   + sL W++ g+ L  a  dg+v++ ++e   +v + s +++ av + +W
   EEA20793.1 146 WILSLDWSHTGEYLLSASFDGKVKVWSVERRACVATHSENDK-AVWSAKW 194
                  5889******************************99877766.5888777 PP

>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.9   0.0    0.0015       2.6     107     159 ..      25      76 ..      14      78 .. 0.78
   2 !   17.7   0.0   1.4e-06    0.0025      76     169 ..      75     170 ..      74     176 .. 0.79
   3 !    6.1   0.0    0.0052       9.3     107     145 ..     151     186 ..     150     198 .. 0.77

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0015
                 EE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE-TT-..-EEEE-TTSSEEE CS
       eIF2A 107 ffspkgklvllaGfgnlaGeleiwdvkkkkkiakaeaana..tlvewspdgryvl 159
                   s+ g++  laG  n  G++++wd ++ ++   +e + a    ++ s+dg+y++
  EEA20793.1  25 CLSEDGRY--LAGTTNN-GHIKVWDLSNGEQFRDYETKGAfgACIDMSNDGKYIA 76 
                 55566665..5788885.**************99988766336799******986 PP

  == domain 2  score: 17.7 bits;  conditional E-value: 1.4e-06
                 EEESSSSCEEEEEECS.CEEEEEEE..EES--EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE..-TT--EEEE-TTSSEEEEEE-TTT-SS CS
       eIF2A  76 viyGkmpakvslfdlk.vkviskle..eqkrNtiffspkgklvllaGfgnlaGeleiwdvkkkkkiakae..aanatlvewspdgryvlTattaprlrv 169
                 +  G+++ ++++f+++ +++ ++l+   ++  ++ fsp gkl++ aG   +   + ++d+++ ++++++   +a+  +++ws +g+y+l a+   +++v
  EEA20793.1  75 IASGHQNGSIYMFSNEtGRMPFSLSglIKPVRAVAFSPGGKLLAAAGDSKV---IVLYDTESGEQVTQLTghSAWILSLDWSHTGEYLLSASFDGKVKV 170
                 567888999999988545555665522588999**************9999...999****999999886115566789**********9997766665 PP

  == domain 3  score: 6.1 bits;  conditional E-value: 0.0052
                 EE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE-TT CS
       eIF2A 107 ffspkgklvllaGfgnlaGeleiwdvkkkkkiakaeaan 145
                  +s +g+++l a f    G++++w v+++ ++a+  + +
  EEA20793.1 151 DWSHTGEYLLSASF---DGKVKVWSVERRACVATHSEND 186
                 59999999999987...6999999999999998876554 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.0   9.6e-05      0.17      55     110 ..      31      90 ..      20      98 .. 0.77
   2 !    8.5   0.0   0.00064       1.1       3      80 ..     105     183 ..     103     193 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 9.6e-05
   WD40_like  55 lilv.vtlDGtillslleneeevenekieedi.stvkvidd..klliGtnkGsiyvfskd 110
                  +l  +t+ G i   +l+n+e+ +  + + +  +++++ +d   ++ G ++Gsiy+fs++
  EEA20793.1  31 RYLAgTTNNGHIKVWDLSNGEQFRDYETKGAFgACIDMSNDgkYIASGHQNGSIYMFSNE 90 
                 556515789************9999999999834667666511566699*********98 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00064
   WD40_like   3 iYsidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvklld.ddlilvvtlDGtillslleneeevenek 80 
                 + ++ +s+ g+l++  g+++ + ++++es+e+v+ +++ +  ++     + ++ +l ++ DG++    +e    v +++
  EEA20793.1 105 VRAVAFSPGGKLLAAAGDSKVIVLYDTESGEQVTQLTGHSAWILSLDWSHtGEYLLSASFDGKVKVWSVERRACVATHS 183
                 678999**********************************999998876515688999*****9888777777666555 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.5   0.0     0.003       5.4     229     259 ..      29      59 ..      10     138 .. 0.80
   2 !   13.2   0.1   1.4e-05     0.025     229     257 ..     155     183 ..     137     207 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.003
                 TTTEEEEEETT-EEEEEETTTTEEEEEEE-- CS
      Nup160 229 gqtylfalsrdgkLrvWnlltgkclatidll 259
                 +  yl+  + +g ++vW+l++g + +  +++
  EEA20793.1  29 DGRYLAGTTNNGHIKVWDLSNGEQFRDYETK 59 
                 6778899999***********9998776665 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 1.4e-05
                 TTTEEEEEETT-EEEEEETTTTEEEEEEE CS
      Nup160 229 gqtylfalsrdgkLrvWnlltgkclatid 257
                 +  yl+++s dgk++vW+++   c+at +
  EEA20793.1 155 TGEYLLSASFDGKVKVWSVERRACVATHS 183
                 5689**********************944 PP

>> Cytochrom_D1  Cytochrome D1 heme domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.3   0.0   2.4e-05     0.043      43      95 ..      26      79 ..      22      99 .. 0.84
   2 !    5.9   0.0    0.0022         4      15      65 ..     124     174 ..     105     188 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 2.4e-05
                  -TT.SSEEEEEETTSEEEEEESSSSSEEEEE.E-SSEEEEEEE--TTSEEEEEE CS
  Cytochrom_D1 43 fasdgRyvyvigRDgkvtliDLwakeivaev.kiGlnarsvavSqddryvivgn 95
                   ++dgRy+   +  g++++ DL + e  ++    G     +++S+d++y++ g 
    EEA20793.1 26 LSEDGRYLAGTTNNGHIKVWDLSNGEQFRDYeTKGAFGACIDMSNDGKYIASGH 79
                  689*********************9955554156999999*********99985 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0022
                   TEEEEEETTT-SEEEEEE-STTEEEEEE-TT.SSEEEEEETTSEEEEEESS CS
  Cytochrom_D1  15 gkvalldgdskeilavletgyalHisrvfasdgRyvyvigRDgkvtliDLw 65 
                     + l d +s e++ +l ++ a   s   +  g y++ ++ Dgkv++  + 
    EEA20793.1 124 KVIVLYDTESGEQVTQLTGHSAWILSLDWSHTGEYLLSASFDGKVKVWSVE 174
                   334566888888888888888888888888888888888888888876554 PP

>> VID27  VID27 C-terminal WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.14   2.5e+02     193     209 ..      23      39 ..      14      50 .. 0.78
   2 !   13.6   0.0   1.5e-05     0.026     139     220 ..      51     135 ..      41     155 .. 0.83

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.14
       VID27 193 gldvsadGrwvlatckt 209
                  ++ s+dGr++ +t+++
  EEA20793.1  23 AICLSEDGRYLAGTTNN 39 
                 57889999999998875 PP

  == domain 2  score: 13.6 bits;  conditional E-value: 1.5e-05
       VID27 139 selkqyaskndfsava.ttekG.yiavasekGdirlfdrlginaktalPalgdpiigldvsadGrwvlatckty.llLiDalike 220
                 +++++y +k  f a     ++G yia + + G i +f +   +   +l  l +p++ +  s  G+ + a+ ++  ++L D++  e
  EEA20793.1  51 EQFRDYETKGAFGACIdMSNDGkYIASGHQNGSIYMFSNETGRMPFSLSGLIKPVRAVAFSPGGKLLAAAGDSKvIVLYDTESGE 135
                 6899********986514445548******************************************9999876516788988765 PP

>> Coatomer_WDAD  Coatomer WD associated region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   1.2e-05     0.022      79     171 ..      69     172 ..      18     197 .. 0.65

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.2e-05
                    XXX...XXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXX......XXXXXXXXXX..XXXXXXXXXXXXXXXXXXX..XXXXXXXXXXXXXXXX CS
  Coatomer_WDAD  79 snr...favlessksvkifknfkekktksikleyqvdkifg......GalLgvkseg.svsfYDweqgklvrridvkk..vknVvwsddgelvalv 162
                    sn+   +a   +++s+  f n +++    ++l+  ++ + +      G lL +  ++ ++++YD e+g++v +++ ++  +    ws +ge++  +
     EEA20793.1  69 SNDgkyIASGHQNGSIYMFSNETGRM--PFSLSGLIKPVRAvafspgGKLLAAAGDSkVIVLYDTESGEQVTQLTGHSawILSLDWSHTGEYLLSA 162
                    44434344444566676666666665..5555444444444445889****9998876999*************96644899999******98776 PP

                    X.XXXXXXXX CS
  Coatomer_WDAD 163 s.kdtvyils 171
                    s + +v + s
     EEA20793.1 163 SfDGKVKVWS 172
                    4234444444 PP

>> Gmad1  Lipoprotein LpqB beta-propeller domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0       4.3   7.7e+03      30      56 ..      26      51 ..      23      60 .. 0.70
   2 ?   12.0   0.2   7.2e-05      0.13      24      94 ..     104     186 ..      95     195 .. 0.72

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 4.3
       Gmad1 30 vSrdgqqvaavtapdggrtLvvgsygg 56
                +S+dg+ +a+ t ++g  +++  s g+
  EEA20793.1 26 LSEDGRYLAGTT-NNGHIKVWDLSNGE 51
                688888888888.66666666555555 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 7.2e-05
       Gmad1  24 dlrsaAvSrdgqqvaavt........apdggrtLvvgsyggeasevl.............eggsltrpSwdrdgalWvvedgaevvravrdd 94 
                  +r++A S+ g+ +aa          ++++g++++           +             +g+ l++ S+d++ ++W ve+ a v++  ++d
  EEA20793.1 104 PVRAVAFSPGGKLLAAAGdskvivlyDTESGEQVTQL---------TghsawilsldwshTGEYLLSASFDGKVKVWSVERRACVATHSEND 186
                 6899999999999999994444444444444444444.........34444444448888888******************99998877754 PP

>> Hira  TUP1-like enhancer of split
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.0    0.0053       9.6      16      41 ..      25      50 ..      19      59 .. 0.83
   2 ?   -3.5   0.0       3.8   6.9e+03      87      97 ..      80      90 ..      66      92 .. 0.75
   3 ?    4.5   0.3     0.014        24      20      47 ..     155     182 ..     140     194 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0053
        Hira 16 fLessgsyLlavtsvgllyvWnvkkk 41
                 L+  g yL+  t++g++ vW++ + 
  EEA20793.1 25 CLSEDGRYLAGTTNNGHIKVWDLSNG 50
                4566779****************876 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 3.8
        Hira 87 sngdgylydks 97
                +ng+ y+++++
  EEA20793.1 80 QNGSIYMFSNE 90
                79999999876 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.014
        Hira  20 sgsyLlavtsvgllyvWnvkkkkvllpp 47 
                  g+yLl  + +g + vW v++++++ ++
  EEA20793.1 155 TGEYLLSASFDGKVKVWSVERRACVATH 182
                 4599******************998754 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (222 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       313  (0.0174578); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 1497.76
//
Query:       EEA20794.1  [L=221]
Description: meiotic recombination protein Ski8/Rec14, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.7e-22   77.9   4.3    2.2e-07   31.5   0.5    4.9  5  WD40           WD domain, G-beta repeat
    7.6e-17   61.4   0.6     0.0035   17.6   0.0    4.1  4  ANAPC4_WD40    Anaphase-promoting complex subunit 4 WD40 doma
    2.5e-06   27.5   0.0     0.0025   17.7   0.0    2.5  2  eIF2A          Eukaryotic translation initiation factor eIF2A
    3.6e-05   23.2   0.0      0.048   13.0   0.0    2.1  2  WD40_like      WD40-like domain
    0.00012   20.9   0.1      0.024   13.3   0.1    2.1  2  Nup160         Nucleoporin Nup120/160
     0.0002   20.0   0.0      0.042   12.4   0.0    2.0  2  Cytochrom_D1   Cytochrome D1 heme domain
     0.0023   17.1   0.0      0.027   13.5   0.0    2.0  2  VID27          VID27 C-terminal WD40-like domain
  ------ inclusion threshold ------
      0.015   14.3   0.0      0.018   14.1   0.0    1.2  1  Coatomer_WDAD  Coatomer WD associated region
       0.05   13.4   0.1       0.13   12.0   0.2    1.6  2  Gmad1          Lipoprotein LpqB beta-propeller domain
       0.16   11.6   1.5        9.5    5.9   0.0    2.3  3  Hira           TUP1-like enhancer of split


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.1   1.8e-05     0.033      14      38 .]      21      45 ..       7      45 .. 0.87
   2 !   12.3   0.0   0.00014      0.25      15      37 ..      64      86 ..      54      87 .. 0.91
   3 !   16.1   0.0   8.6e-06     0.015      11      38 .]     102     129 ..      92     129 .. 0.81
   4 !   31.5   0.5   1.2e-10   2.2e-07       2      38 .]     134     171 ..     133     171 .. 0.91
   5 ?   -0.1   0.0       1.1     2e+03       4      26 ..     178     204 ..     175     216 .. 0.53

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 1.8e-05
                EEEEEETTSSEEEEE.ETTSEEEEEE CS
        WD40 14 tslafspdgawlasG.sdDgtvriWd 38
                ++++ s dg++la G + +g++++Wd
  EEA20794.1 21 WAICLSEDGRYLA-GtTNNGHIKVWD 45
                57788******97.7457*******9 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 0.00014
                EEEEETTSSEEEEEETTSEEEEE CS
        WD40 15 slafspdgawlasGsdDgtvriW 37
                +++ s dg+++asG+ +g+++++
  EEA20794.1 64 CIDMSNDGKYIASGHQNGSIYMF 86
                8999****************986 PP

  == domain 3  score: 16.1 bits;  conditional E-value: 8.6e-06
                 SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  11 ssvtslafspdgawlasGsdDgtvriWd 38 
                 ++v+++afsp g++la+++d + + ++d
  EEA20794.1 102 KPVRAVAFSPGGKLLAAAGDSKVIVLYD 129
                 689*************999677777666 PP

  == domain 4  score: 31.5 bits;  conditional E-value: 1.2e-10
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 ++++ ltGH  ++ sl++s+ g +l+s+s Dg+v++W+
  EEA20794.1 134 EQVTQLTGHsAWILSLDWSHTGEYLLSASFDGKVKVWS 171
                 678899***666****************99*******5 PP

  == domain 5  score: -0.1 bits;  conditional E-value: 1.1
                 EEEEESS.SSEEEEEEETTSSE.........EE CS
        WD40   4 lrtltGH.ssvtslafspdgaw.........la 26 
                 + t +   + v+s       +w         +a
  EEA20794.1 178 VATHSENdKAVWSA------KWlpkigrtegFA 204
                 45444444449998......6655544455544 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.4   0.0   0.00017       0.3      43      79 ..      22      58 ..       5      65 .. 0.88
   2 !   11.1   0.0    0.0002      0.36      45      74 ..      66      95 ..      60     102 .. 0.88
   3 !   17.6   0.0     2e-06    0.0035      39      80 ..     102     143 ..      97     146 .. 0.92
   4 !   17.3   0.4   2.4e-06    0.0044      40      89 ..     145     193 ..     140     196 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00017
  ANAPC4_WD40 43 sLaWkpdgklLavaysdgevrlldaesgkvvhslsvk 79
                 +++ ++dg+ La  +++g++++ d ++g+  + +++k
   EEA20794.1 22 AICLSEDGRYLAGTTNNGHIKVWDLSNGEQFRDYETK 58
                 578899**********************998887765 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.0002
  ANAPC4_WD40 45 aWkpdgklLavaysdgevrlldaesgkvvh 74
                   ++dgk +a ++++g++ +++ e+g++  
   EEA20794.1 66 DMSNDGKYIASGHQNGSIYMFSNETGRMPF 95
                 6689**********************9865 PP

  == domain 3  score: 17.6 bits;  conditional E-value: 2e-06
  ANAPC4_WD40  39 sevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvks 80 
                  + vr++a++p gklLa a +   + l+d esg+ v +l+ +s
   EEA20794.1 102 KPVRAVAFSPGGKLLAAAGDSKVIVLYDTESGEQVTQLTGHS 143
                  579********************************9998765 PP

  == domain 4  score: 17.3 bits;  conditional E-value: 2.4e-06
  ANAPC4_WD40  40 evrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                   + sL W++ g+ L  a  dg+v++ ++e   +v + s +++ av + +W
   EEA20794.1 145 WILSLDWSHTGEYLLSASFDGKVKVWSVERRACVATHSENDK-AVWSAKW 193
                  5889******************************99877766.5888777 PP

>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.4   0.1   0.00099       1.8     105     159 ..      22      75 ..       5      80 .. 0.79
   2 !   17.7   0.0   1.4e-06    0.0025      76     169 ..      74     169 ..      73     174 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00099
                 EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE-TT-..-EEEE-TTSSEEE CS
       eIF2A 105 tiffspkgklvllaGfgnlaGeleiwdvkkkkkiakaeaana..tlvewspdgryvl 159
                 +i  s+ g++  laG  n  G++++wd ++ ++   +e + a    ++ s+dg+y++
  EEA20794.1  22 AICLSEDGRY--LAGTTNN-GHIKVWDLSNGEQFRDYETKGAfgACIDMSNDGKYIA 75 
                 5666666766..5788885.**************9998876633679********96 PP

  == domain 2  score: 17.7 bits;  conditional E-value: 1.4e-06
                 EEESSSSCEEEEEECS.CEEEEEEE..EES--EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE..-TT--EEEE-TTSSEEEEEE-TTT-SS CS
       eIF2A  76 viyGkmpakvslfdlk.vkviskle..eqkrNtiffspkgklvllaGfgnlaGeleiwdvkkkkkiakae..aanatlvewspdgryvlTattaprlrv 169
                 +  G+++ ++++f+++ +++ ++l+   ++  ++ fsp gkl++ aG   +   + ++d+++ ++++++   +a+  +++ws +g+y+l a+   +++v
  EEA20794.1  74 IASGHQNGSIYMFSNEtGRMPFSLSglIKPVRAVAFSPGGKLLAAAGDSKV---IVLYDTESGEQVTQLTghSAWILSLDWSHTGEYLLSASFDGKVKV 169
                 567888999999988545555665522588999**************9999...999****999999886115566789**********9997766665 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.0   0.0   2.7e-05     0.048      29     110 ..       3      89 ..       1      97 [. 0.76
   2 !    8.5   0.0   0.00063       1.1       3      80 ..     104     182 ..     102     192 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 2.7e-05
   WD40_like  29 leslesvsivesfedSvifvkllddd.lilvv.tlDGtillslleneeevenekieedi.stvkvidd..klliGtnkGsiyvfskd 110
                 +++ ++ ++ + +++   ++  l++d  +l + t+ G i   +l+n+e+ +  + + +  +++++ +d   ++ G ++Gsiy+fs++
  EEA20794.1   3 FKTVTKNTSTDAIKEPDTWAICLSEDgRYLAGtTNNGHIKVWDLSNGEQFRDYETKGAFgACIDMSNDgkYIASGHQNGSIYMFSNE 89 
                 566666667777777777777788777777652689************9999999999834667666511566699*********98 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00063
   WD40_like   3 iYsidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvklld.ddlilvvtlDGtillslleneeevenek 80 
                 + ++ +s+ g+l++  g+++ + ++++es+e+v+ +++ +  ++     + ++ +l ++ DG++    +e    v +++
  EEA20794.1 104 VRAVAFSPGGKLLAAAGDSKVIVLYDTESGEQVTQLTGHSAWILSLDWSHtGEYLLSASFDGKVKVWSVERRACVATHS 182
                 678999**********************************999998876515688999*****9888777777666555 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.0   0.0    0.0022       3.9     225     259 ..      24      58 ..       3     135 .. 0.78
   2 !   13.3   0.1   1.3e-05     0.024     227     257 ..     153     182 ..     130     203 .. 0.82

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.0022
                 ....TTTEEEEEETT-EEEEEETTTTEEEEEEE-- CS
      Nup160 225 vveigqtylfalsrdgkLrvWnlltgkclatidll 259
                 + +++  yl+  + +g ++vW+l++g + +  +++
  EEA20794.1  24 CLSEDGRYLAGTTNNGHIKVWDLSNGEQFRDYETK 58 
                 5555778999999************9998776665 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 1.3e-05
                 ..TTTEEEEEETT-EEEEEETTTTEEEEEEE CS
      Nup160 227 eigqtylfalsrdgkLrvWnlltgkclatid 257
                 + +  yl+++s dgk++vW+++   c+at +
  EEA20794.1 153 H-TGEYLLSASFDGKVKVWSVERRACVATHS 182
                 4.6689**********************944 PP

>> Cytochrom_D1  Cytochrome D1 heme domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.4   0.0   2.3e-05     0.042      43      95 ..      25      78 ..      20      98 .. 0.84
   2 !    5.9   0.0    0.0022         4      15      65 ..     123     173 ..     104     187 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2.3e-05
                  -TT.SSEEEEEETTSEEEEEESSSSSEEEEE.E-SSEEEEEEE--TTSEEEEEE CS
  Cytochrom_D1 43 fasdgRyvyvigRDgkvtliDLwakeivaev.kiGlnarsvavSqddryvivgn 95
                   ++dgRy+   +  g++++ DL + e  ++    G     +++S+d++y++ g 
    EEA20794.1 25 LSEDGRYLAGTTNNGHIKVWDLSNGEQFRDYeTKGAFGACIDMSNDGKYIASGH 78
                  689*********************9955554156999999*********99985 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0022
                   TEEEEEETTT-SEEEEEE-STTEEEEEE-TT.SSEEEEEETTSEEEEEESS CS
  Cytochrom_D1  15 gkvalldgdskeilavletgyalHisrvfasdgRyvyvigRDgkvtliDLw 65 
                     + l d +s e++ +l ++ a   s   +  g y++ ++ Dgkv++  + 
    EEA20794.1 123 KVIVLYDTESGEQVTQLTGHSAWILSLDWSHTGEYLLSASFDGKVKVWSVE 173
                   334566888888888888888888888888888888888888888876554 PP

>> VID27  VID27 C-terminal WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0      0.08   1.4e+02     192     209 ..      21      38 ..       3      46 .. 0.71
   2 !   13.5   0.0   1.5e-05     0.027     139     220 ..      50     134 ..      40     153 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.08
       VID27 192 igldvsadGrwvlatckt 209
                   ++ s+dGr++ +t+++
  EEA20794.1  21 WAICLSEDGRYLAGTTNN 38 
                 468999999999999875 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 1.5e-05
       VID27 139 selkqyaskndfsava.ttekG.yiavasekGdirlfdrlginaktalPalgdpiigldvsadGrwvlatckty.llLiDalike 220
                 +++++y +k  f a     ++G yia + + G i +f +   +   +l  l +p++ +  s  G+ + a+ ++  ++L D++  e
  EEA20794.1  50 EQFRDYETKGAFGACIdMSNDGkYIASGHQNGSIYMFSNETGRMPFSLSGLIKPVRAVAFSPGGKLLAAAGDSKvIVLYDTESGE 134
                 6899********986514445548******************************************9999876516788988765 PP

>> Coatomer_WDAD  Coatomer WD associated region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0     1e-05     0.018      79     172 ..      68     172 ..       6     197 .. 0.65

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 1e-05
                    XXX...XXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXX......XXXXXXXXXX..XXXXXXXXXXXXXXXXXXX..XXXXXXXXXXXXXXXX CS
  Coatomer_WDAD  79 snr...favlessksvkifknfkekktksikleyqvdkifg......GalLgvkseg.svsfYDweqgklvrridvkk..vknVvwsddgelvalv 162
                    sn+   +a   +++s+  f n +++    ++l+  ++ + +      G lL +  ++ ++++YD e+g++v +++ ++  +    ws +ge++  +
     EEA20794.1  68 SNDgkyIASGHQNGSIYMFSNETGRM--PFSLSGLIKPVRAvafspgGKLLAAAGDSkVIVLYDTESGEQVTQLTGHSawILSLDWSHTGEYLLSA 161
                    44444344445577777766666666..5555544444444445899****9998876999*************96654899999******98776 PP

                    X.XXXXXXXXX CS
  Coatomer_WDAD 163 s.kdtvyilsy 172
                    s + +v + s 
     EEA20794.1 162 SfDGKVKVWSV 172
                    42444444444 PP

>> Gmad1  Lipoprotein LpqB beta-propeller domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0         4   7.2e+03      30      56 ..      25      50 ..      21      59 .. 0.70
   2 ?   12.0   0.2   7.1e-05      0.13      24      94 ..     103     185 ..      94     194 .. 0.72

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 4
       Gmad1 30 vSrdgqqvaavtapdggrtLvvgsygg 56
                +S+dg+ +a+ t ++g  +++  s g+
  EEA20794.1 25 LSEDGRYLAGTT-NNGHIKVWDLSNGE 50
                788888888888.66666666555555 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 7.1e-05
       Gmad1  24 dlrsaAvSrdgqqvaavt........apdggrtLvvgsyggeasevl.............eggsltrpSwdrdgalWvvedgaevvravrdd 94 
                  +r++A S+ g+ +aa          ++++g++++           +             +g+ l++ S+d++ ++W ve+ a v++  ++d
  EEA20794.1 103 PVRAVAFSPGGKLLAAAGdskvivlyDTESGEQVTQL---------TghsawilsldwshTGEYLLSASFDGKVKVWSVERRACVATHSEND 185
                 6899999999999999994444444444444444444.........34444444448888888******************99998877754 PP

>> Hira  TUP1-like enhancer of split
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.0    0.0053       9.5      16      41 ..      24      49 ..      18      58 .. 0.83
   2 ?   -3.5   0.0       3.8   6.8e+03      87      97 ..      79      89 ..      65      91 .. 0.75
   3 ?    4.5   0.3     0.013        24      20      47 ..     154     181 ..     139     193 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0053
        Hira 16 fLessgsyLlavtsvgllyvWnvkkk 41
                 L+  g yL+  t++g++ vW++ + 
  EEA20794.1 24 CLSEDGRYLAGTTNNGHIKVWDLSNG 49
                4566779****************876 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 3.8
        Hira 87 sngdgylydks 97
                +ng+ y+++++
  EEA20794.1 79 QNGSIYMFSNE 89
                79999999876 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.013
        Hira  20 sgsyLlavtsvgllyvWnvkkkkvllpp 47 
                  g+yLl  + +g + vW v++++++ ++
  EEA20794.1 154 TGEYLLSASFDGKVKVWSVERRACVATH 181
                 4599******************998754 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (221 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       326  (0.0181828); expected 358.6 (0.02)
Passed bias filter:                      300  (0.0167327); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.54u 0.30s 00:00:00.84 Elapsed: 00:00:00.49
# Mc/sec: 1345.29
//
Query:       EEA20795.1  [L=346]
Description: septin [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   5.9e-114  380.1   1.5     7e-114  379.9   1.5    1.0  1  Septin        Septin
    3.5e-08   33.5   0.0    7.4e-08   32.5   0.0    1.6  1  MMR_HSR1      50S ribosome-binding GTPase
    1.1e-05   24.9   0.0    1.8e-05   24.1   0.0    1.4  1  AIG1          AIG1 family
    3.5e-05   23.4   1.4      0.023   14.3   0.1    2.4  2  GTP_EFTU      Elongation factor Tu GTP binding domain
    5.8e-05   23.1   0.8    0.00046   20.1   0.1    2.2  2  RsgA_GTPase   RsgA GTPase
    0.00057   20.0   1.6       0.81    9.7   0.2    2.6  3  Dynamin_N     Dynamin family
    0.00069   19.2   0.1     0.0042   16.6   0.0    2.2  2  AAA_7         P-loop containing dynein motor region
     0.0023   17.1   0.1     0.0042   16.3   0.1    1.3  1  NB-ARC        NB-ARC domain
     0.0049   17.3   0.0      0.013   15.9   0.0    1.9  1  AAA_16        AAA ATPase domain
     0.0092   15.4   0.1       0.33   10.3   0.0    2.2  2  Gtr1_RagA     Gtr1/RagA G protein conserved region
  ------ inclusion threshold ------
      0.012   16.2   1.0      0.018   15.5   0.2    1.7  1  ABC_tran      ABC transporter
      0.013   15.8   0.0      0.026   14.8   0.0    1.6  1  AAA_22        AAA domain
       0.04   14.1   0.0      0.081   13.1   0.0    1.5  1  Roc           Ras of Complex, Roc, domain of DAPkinase
      0.058   12.6   1.4       0.25   10.5   1.0    1.8  1  G-alpha       G-protein alpha subunit
      0.067   12.5   0.0       0.13   11.6   0.0    1.4  1  FtsK_SpoIIIE  FtsK/SpoIIIE family
       0.15   11.9   0.0       0.31   10.8   0.0    1.5  1  AAA_29        P-loop containing region of AAA domain


Domain annotation for each model (and alignments):
>> Septin  Septin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  379.9   1.5  6.2e-117    7e-114       1     278 [.      36     312 ..      36     315 .. 0.98

  Alignments for each domain:
  == domain 1  score: 379.9 bits;  conditional E-value: 6.2e-117
                 XEEEEEEEEEEBTTSSCCCCCCTTSSSS------------------S-EEEEEEEEETTCEEEEEEEE---BSSSSSHHCCCHHHHHHHHHHHHHHHHH CS
      Septin   1 kgieftlmvvGesglGkttlintlfetdlieeekleeasekkkktveikkkkvvieedgvklnltviDtpgfGdavdnskswepiveyideqfeeylre 99 
                 +g++f++m+vG+ glGk+tlint+f+++li+++   +++e  ++t+ei++ +++iee+gv+l+l+++Dtpg+Gd+v+n+++w+piv+yi++q+++ylr+
  EEA20795.1  36 RGFQFNVMCVGQTGLGKSTLINTIFASHLIDSKGRLTPNEPVRSTTEIQTVSHIIEENGVRLRLNIVDTPGYGDQVNNDRCWDPIVKYIKDQHSAYLRK 134
                 69************************************************************************************************* PP

                 CTSS--.SS-----EEEEEEEE-TTSSSS-HHHHHHHHHHTTTS-EEEEESSGGGS-HHHHHHHHHHHHHHHHHTT--------SSSS-SCCHHHHHHH CS
      Septin 100 esklkR.kkivDkRvHaclyfisPtghglkpldvelmkklsekvnliPviaKaDtltkeElkefKkkireeleeeeikiyklpdeeededeeakelsek 197
                 e +++R + i+D+R+H+cl+fi+P+gh lkp+d+ ++kkls+ vn++PviaK+D+lt eE +efK++i+ee++ +++k+y  +d +e +dee + ++ +
  EEA20795.1 135 ELTAQReRYIQDTRIHCCLFFIQPSGHALKPIDIVVLKKLSDVVNVVPVIAKSDSLTLEERQEFKERIKEEFTFHNLKMYP-YDNDELDDEE-RVMNAQ 231
                 ******8889***********************************************************************.*******999.88999* PP

                 HHHC-SEEB-SSSSEEEESSSEEEEEEETTEEEETT-TTT-SCCHHHHHHHHHCHHHHHHHHHHTHHHHHHHHHH-XXXXX CS
      Septin 198 lkeslPfaivgsneliekkgkkvrgRkypWGvvevenekhsdFlkLrklllkthledLkevteellYetyRseklsklkek 278
                 +k  +Pfa+vgs++ i  +gk+vrgR+ +WGv++ve+e+h++F+ Lr++l++thl+dL+e+t++++Yet+R+++l +lke+
  EEA20795.1 232 IKDIIPFAVVGSEKNIVVNGKQVRGRQNRWGVINVEDENHCEFVYLRNFLTRTHLQDLIETTSQIHYETFRAKQLMALKES 312
                 ***************************************************************************998865 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.5   0.0   6.6e-11   7.4e-08       1     101 [.      41     174 ..      41     195 .. 0.54

  Alignments for each domain:
  == domain 1  score: 32.5 bits;  conditional E-value: 6.6e-11
                 EEEEEESTTSSHHHHHHHHHT.....STE.EESSST.TSSSSEEEEE..EEETT..EEEEEEECGGC................SS...HHHHHH...HH CS
    MMR_HSR1   1 evaivGrpNvGKStLinaltg.....eka.ivsdkp.gtTrdinegr..vklkg..keielvDtpGl................ie...gaseek...gl 66 
                 +v++vG++  GKStLin+++      +k   + ++p   T++i++    ++++g   ++++vDtpG                 i+   +a  +k     
  EEA20795.1  41 NVMCVGQTGLGKSTLINTIFAshlidSKGrLTPNEPvRSTTEIQTVShiIEENGvrLRLNIVDTPGYgdqvnndrcwdpivkyIKdqhSAYLRKeltAQ 139
                 5899***************9733332222122333333333333322113333333569*******555555555555544432211222222211223 PP

                 HHHHHHHHCTSEEEEEEETTTTCSHHHHHHHHHHH CS
    MMR_HSR1  67 gkaflaleeadlillvvdaseeklkpldeeleell 101
                 ++++ +  + +  l+ ++ s + lkp+d  + + l
  EEA20795.1 140 RERYIQDTRIHCCLFFIQPSGHALKPIDIVVLKKL 174
                 33333344567777777655556777776666665 PP

>> AIG1  AIG1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.0   1.6e-08   1.8e-05       2      68 ..      41     115 ..      40     132 .. 0.73

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 1.6e-08
                 EEEEESSTTSSHHHHHHHHHTS--SS--TTTS...--..-SS-EEEEE..EETT..EEEEEEE--SCCCTTCCHHC CS
        AIG1   2 tivlvGktgnGkSaTgNsilgkkaFesklsaq...sv..tkkcqkksr..twdg..kkinViDTPglfdlsvsadk 68 
                 +++ vG+tg GkS+ +N+i  ++  +sk + +   +v  t++ q++s   +++g   ++n++DTPg  d  v++d+
  EEA20795.1  41 NVMCVGQTGLGKSTLINTIFASHLIDSKGRLTpnePVrsTTEIQTVSHiiEENGvrLRLNIVDTPGYGDQ-VNNDR 115
                 7899***********************98754112443377888999853444455679*******8764.44444 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.1     2e-05     0.023       5      82 ..      41     109 ..      39     114 .. 0.71
   2 !    7.9   0.1    0.0018         2     121     179 ..     176     247 ..     164     305 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2e-05
                 EEEEEESTTSSHHHHHHHHHHHTTSSCHHHHHHHHHSTHCHSHHHHHHTSCSSCEEEEEE.TTCSSEEEEEEEESSSGG CS
    GTP_EFTU   5 nigiighvDhGKtTLtdrLlyktgaiskkgekaeeervlDtlkeErergiTiksaaisle.ketkkylinliDtPGHvd 82 
                 n++ +g +  GK+TL+ ++ +++ ++sk g      r    +++E  r  T   ++ ++  +++ + ++n++DtPG  d
  EEA20795.1  41 NVMCVGQTGLGKSTLINTIFASHLIDSK-G------R---LTPNEPVRSTTEIQTVSHIIeENGVRLRLNIVDTPGYGD 109
                 89999**************988777666.2......2...34556666555333332222247999**********877 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0018
                 TTTEEEEEEESCGST.HHHHHHHHHHHHHHHHHHHHHHHHHHHTTT..............TTEEEEEEBTTTTB CS
    GTP_EFTU 121 egvpiivfiNKmDrl.kaelkeiveevkqklsrkeeklekygekge..............kevpvvfgSalkge 179
                   v+++ +i K D l  +e +e +e +k+++  + ++l+ y+++++              +++p++ + + k+ 
  EEA20795.1 176 DVVNVVPVIAKSDSLtLEERQEFKERIKEEF--TFHNLKMYPYDNDelddeervmnaqikDIIPFAVVGSEKNI 247
                 5588***********9888999999999999..55566666666655566666666655556666666555555 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   0.1   4.1e-07   0.00046     101     160 ..      41     106 ..      18     110 .. 0.67
   2 ?    0.8   0.0      0.36     4e+02      44      74 ..     175     204 ..     159     240 .. 0.64

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 4.1e-07
                  EEEEECSTTSSHHHHHHHHCTT-----S--------------SEEEEEETT.TEE.....EESS-S CS
  RsgA_GTPase 101 tsvlvGqSGvGKStLinallpelelktgevseklgrGkhTTtavellelae.ggl.....liDtPG 160
                   ++ vGq+G GKStLin++  ++ +  +   + ++  + TT  +++ ++ e +g+     ++DtPG
   EEA20795.1  41 NVMCVGQTGLGKSTLINTIFASHLIDSKGRLTPNEPVRSTTEIQTVSHIIEeNGVrlrlnIVDTPG 106
                  34568**************99876666666666777788887776666544344333333888888 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.36
                  HTT-EEEEEEE-GGG--HHHHHHHHHHHHHH CS
  RsgA_GTPase  44 ekgiepvivlnKiDlleeeeeleelkeelea 74 
                  +  +++v v+ K D l+ ee  +e+ke++++
   EEA20795.1 175 SDVVNVVPVIAKSDSLTLEE-RQEFKERIKE 204
                  4557888899****999888.4444444332 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   0.2   0.00072      0.81       1      29 [.      42      69 ..      42      87 .. 0.79
   2 !    8.8   0.0    0.0014       1.6     100     129 ..      96     128 ..      78     134 .. 0.80
   3 ?   -3.2   0.0         7   7.8e+03      54      58 ..     197     201 ..     175     234 .. 0.56

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00072
                EEEEEBTTTTHHHHHHHHHTS--S---SS CS
   Dynamin_N  1 iavvGsqSsGKSSvlnaLlgedilprgpn 29
                ++ vG++  GKS+++n +  ++ l  +++
  EEA20795.1 42 VMCVGQTGLGKSTLINTIFASH-LIDSKG 69
                6789**************9998.444444 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0014
                 S-SEEEEE---B-SSSGTTS..HHHHHHH.STT CS
   Dynamin_N 100 vkgltlvDlPGldsvnkrdq..elvkeyi.kka 129
                 + +l++vD+PG+ ++ ++d   + + +yi +++
  EEA20795.1  96 RLRLNIVDTPGYGDQVNNDRcwDPIVKYIkDQH 128
                 67899*******998888888999999995444 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 7
                 SEEEE CS
   Dynamin_N  54 elkek 58 
                 e+ke+
  EEA20795.1 197 EFKER 201
                 22222 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   3.7e-06    0.0042      33      85 ..      39      93 ..      25     112 .. 0.78
   2 ?   -0.8   0.0      0.86   9.6e+02     126     155 ..     121     153 ..     116     167 .. 0.76

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 3.7e-06
       AAA_7 33 kkpvllvGptGtGKtviikd.llkkld.kekylsltinfsaqtsanqlqdiiesk 85
                + +v++vG+tG GK+++i++ + ++l  ++  l+ +  + ++t+ +++ +iie++
  EEA20795.1 39 QFNVMCVGQTGLGKSTLINTiFASHLIdSKGRLTPNEPVRSTTEIQTVSHIIEEN 93
                468*****************76666542566666777788888888888888875 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.86
       AAA_7 126 lRqlldyggwYdrkklefk...eikdvqlvaam 155
                 ++ + d++  Y rk+l+ +   +i+d+ + ++ 
  EEA20795.1 121 VKYIKDQHSAYLRKELTAQrerYIQDTRIHCCL 153
                 677789999999999855433379999998885 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.1   3.7e-06    0.0042       6      43 ..      27      62 ..      23      69 .. 0.88

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 3.7e-06
                HHHHHHHHCTTTSCSEEEEEEESTTSSHHHHHHHHCCS CS
      NB-ARC  6 ekviekLlekdelqslvvalvGmgGvGKttlakqilnk 43
                 ++ +kLl k ++q + v  vG  G+GK+tl++ i+ +
  EEA20795.1 27 SQIEKKLL-KRGFQ-FNVMCVGQTGLGKSTLINTIFAS 62
                68999***.999*9.88999***************987 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   1.2e-05     0.013      26      63 ..      41      74 ..      23     244 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 1.2e-05
      AAA_16 26 lvllsGesGvGKsslvrellralekdggiflrgkcdql 63
                +v+++G+ G GKs+l+++++ +   d     +g+ + +
  EEA20795.1 41 NVMCVGQTGLGKSTLINTIFASHLID----SKGRLTPN 74
                799****************9866555....34444443 PP

>> Gtr1_RagA  Gtr1/RagA G protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.3   0.0    0.0003      0.33       2      64 ..      42     113 ..      41     133 .. 0.72
   2 ?    2.8   0.1     0.055        62     105     141 ..     171     207 ..     162     221 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.0003
   Gtr1_RagA   2 vLLmGksgsGKtsmrsiiFdnylardtlrlgati......dvek.sevrflg..nltlnlwDcgGqeafvee 64 
                 v+ +G+ g GK+++ + iF+  l     rl+         +++  s++   +   l ln++D +G  + v++
  EEA20795.1  42 VMCVGQTGLGKSTLINTIFASHLIDSKGRLTPNEpvrsttEIQTvSHIIEENgvRLRLNIVDTPGYGDQVNN 113
                 7889****************99998888887544333333433213432222125799*******9988877 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.055
   Gtr1_RagA 105 lrqyspeakvfvlihKmDliqedereeifeerkeeir 141
                 l++ s  ++v   i K D ++ +er+e  e++kee +
  EEA20795.1 171 LKKLSDVVNVVPVIAKSDSLTLEERQEFKERIKEEFT 207
                 6788888999999****************99999865 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.5   0.2   1.6e-05     0.018      14      51 ..      42      79 ..      39     152 .. 0.69

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1.6e-05
                EEEEESTTSSHHHHHHHHT.TSS--SEEEEEETTCEGGG CS
                xxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxx RF
    ABC_tran 14 vaivGenGaGKStLlklla.gllkpteGeilldgkdlke 51
                v  vG++G GKStL++++   +l + +G+++  ++++++
  EEA20795.1 42 VMCVGQTGLGKSTLINTIFaSHLIDSKGRLT-PNEPVRS 79
                5679************986155667888873.3344444 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.8   0.0   2.3e-05     0.026       8      36 ..      42      70 ..      39     159 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 2.3e-05
      AAA_22  8 lvvtGesGtGKTtllrrlleqldeeakae 36
                ++++G++G GK+tl+++++ ++ +++k +
  EEA20795.1 42 VMCVGQTGLGKSTLINTIFASHLIDSKGR 70
                68*****************9997765544 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   7.3e-05     0.081       2      65 ..      42     106 ..      41     117 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 7.3e-05
                 EEEESSTTSSHHHHHHCHCT-CCC-EE.ETTTTEEEEE.EECGGSGGCTTBTTTTCEEEEEEEE-S CS
         Roc   2 vvlvGdsgvGKtsllkrfvedkfseke.kstigvdflt.kevtkikgvendkkvkkvklniWDtaG 65 
                 v++vG++g GK++l++ +  ++  +++ + t    + + +e+++++++ ++ +  +++lni Dt G
  EEA20795.1  42 VMCVGQTGLGKSTLINTIFASHLIDSKgRLTPNEPVRStTEIQTVSHIIEE-NGVRLRLNIVDTPG 106
                 89**************98887775544044544444332445555555444.45569999999987 PP

>> G-alpha  G-protein alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   1.0   0.00022      0.25      10      69 ..      28      96 ..      22     212 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00022
                XXXXXXXXXXE..EEEEEEEESTTSSHHHHHHHHH...HHCS--........--HHHHHCCHHHHHHHHHH CS
     G-alpha 10 slkaerkarkkkrevkllllGqseSGKsTilkqlk...llykkg........fseeelatwraviqlnivr 69
                ++++  k  k+ ++++++++Gq + GKsT+++ +    l+  kg         s+ e++t   +i +n vr
  EEA20795.1 28 QIEK--KLLKRGFQFNVMCVGQTGLGKSTLINTIFashLIDSKGrltpnepvRSTTEIQTVSHIIEENGVR 96
                3333..345556799*****************997333333444665555544444455566666666555 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   0.00012      0.13      40      64 ..      40      64 ..      13      70 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00012
                  .SEEEE--TTSSHHHHHHHHHHHHH CS
  FtsK_SpoIIIE 40 shllvaGatgsGKStalntLilSla 64
                   +++ +G tg GKSt +nt+ +S +
    EEA20795.1 40 FNVMCVGQTGLGKSTLINTIFASHL 64
                  69******************99976 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00027      0.31      24      42 ..      41      59 ..      30      68 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00027
      AAA_29 24 atlltGpsGsGKSTllDAi 42
                +++ +G++G GKSTl+  i
  EEA20795.1 41 NVMCVGQTGLGKSTLINTI 59
                57889**********9665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (346 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       578  (0.0322383); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        77  (0.00429472); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              16  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.42
# Mc/sec: 2481.28
//
Query:       EEA20796.1  [L=200]
Description: guanylate kinase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.1e-65  218.3   0.0    7.4e-65  218.0   0.0    1.0  1  Guanylate_kin  Guanylate kinase
    3.3e-06   27.6   0.4    1.2e-05   25.8   0.4    1.8  1  AAA_16         AAA ATPase domain
    1.2e-05   25.5   0.2     0.0001   22.5   0.2    2.2  1  AAA_33         AAA domain
    2.3e-05   24.5   0.0    3.7e-05   23.8   0.0    1.4  1  MMR_HSR1       50S ribosome-binding GTPase
    2.8e-05   24.7   0.6    0.00011   22.7   0.3    2.1  2  AAA_18         AAA domain
     0.0002   21.7   0.0    0.00054   20.3   0.0    1.7  2  AAA_22         AAA domain
    0.00033   21.2   0.0    0.00051   20.6   0.0    1.7  1  ABC_tran       ABC transporter
    0.00052   20.3   0.0    0.00091   19.5   0.0    1.6  2  AAA_28         AAA domain
     0.0013   18.6   0.0     0.0024   17.8   0.0    1.4  1  RsgA_GTPase    RsgA GTPase
     0.0015   18.3   0.2      0.018   14.8   0.2    2.2  1  AAA_24         AAA domain
      0.002   17.7   0.0     0.0033   17.0   0.0    1.3  1  AAA_7          P-loop containing dynein motor region
     0.0025   18.2   0.0     0.0039   17.6   0.0    1.5  1  RNA_helicase   RNA helicase
     0.0035   16.5   0.0     0.0059   15.7   0.0    1.4  1  T2SSE          Type II/IV secretion system protein
      0.007   16.4   0.0      0.014   15.4   0.0    1.6  1  AAA_14         AAA domain
     0.0074   16.2   0.0      0.016   15.1   0.0    1.6  1  NTPase_1       NTPase
      0.008   16.1   0.0      0.015   15.3   0.0    1.4  1  NACHT          NACHT domain
     0.0081   15.9   0.1      0.015   15.0   0.1    1.4  1  AAA_29         P-loop containing region of AAA domain
     0.0094   16.4   0.0      0.027   14.9   0.0    2.0  1  AAA            ATPase family associated with various cellular
  ------ inclusion threshold ------
      0.011   15.0   0.0       0.12   11.6   0.0    2.0  1  DUF2075        Uncharacterized conserved protein (DUF2075)
      0.012   15.4   0.0      0.019   14.7   0.0    1.5  1  AAA_30         AAA domain
      0.012   15.6   0.0      0.014   15.3   0.0    1.2  1  Rad17          Rad17 P-loop domain
      0.022   14.7   0.0      0.031   14.2   0.0    1.7  1  ATPase_2       ATPase domain predominantly from Archaea
      0.027   14.5   0.1       0.14   12.2   0.0    2.1  2  AAA_5          AAA domain (dynein-related subfamily)
      0.043   14.3   0.1       0.24   11.9   0.0    1.9  2  AAA_23         AAA domain
      0.092   13.1   0.0       0.15   12.4   0.0    1.4  1  AAA_19         AAA domain
      0.096   11.5   0.0       0.14   10.9   0.0    1.2  1  Adeno_IVa2     Adenovirus IVa2 protein
       0.11   12.0   0.0       0.26   10.9   0.0    1.5  1  cobW           CobW/HypB/UreG, nucleotide-binding domain
       0.16   11.8   0.3        1.5    8.6   0.0    2.3  2  dNK            Deoxynucleoside kinase


Domain annotation for each model (and alignments):
>> Guanylate_kin  Guanylate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  218.0   0.0   1.2e-67   7.4e-65       2     179 ..       9     190 ..       8     192 .. 0.98

  Alignments for each domain:
  == domain 1  score: 218.0 bits;  conditional E-value: 1.2e-67
                    SSEEEEESTTTSSHHHHHHHHHHHSTTTEEE--EEESS---TTS-TTTSEEE--HHHHHHHHHTTTEEEEEEETTEEEEEEHHHHHHHHHTTSEEE CS
  Guanylate_kin   2 rrpvvlvgpsgaGksslkkaLlselpekfgvsvshtTrdprkgevdGkdYyFvskeemekdiskneflEaaefsgnlygtsveaieevlekgkivi 97 
                     rpvv++gpsg+Gks+l k L++e+p++fg+s+shtTr+pr+ge+dG++YyF +k+ + k +++n f+E+a+f gn ygtsv+a+++++ k++i+i
     EEA20796.1   9 YRPVVISGPSGTGKSTLLKRLFAEFPDTFGFSISHTTRAPRAGEEDGREYYFTTKDDFLKLVDENGFIEHAQFGGNFYGTSVQAVRNIASKQRICI 104
                    69********************************************************************************************** PP

                    EE--CHHHHHHHHTTTTEEEEEEEESSHHHHHHHHTTSSSSHHHHHHHHHHHHHHHHGGG.C...SSEEEEESSHHHHHHHHHHHH CS
  Guanylate_kin  98 LDvdiqavkqlrkaelspiivFikppslkelqrrlksrgkeqeeklakrlaaaekelqey.e...fdvvivnddleealkklkell 179
                    LD+++++vkq+++++l+++++F+ ppsl+el+rrl++rg+e+e +l+krla+a++el+++     +d ++vnddle+a+++l++ +
     EEA20796.1 105 LDIEMEGVKQVKRTDLNARFLFLSPPSLEELERRLRGRGTETEDSLNKRLAQARNELEYSrQpgaHDKIVVNDDLEKAYTELRDWI 190
                    *********************************************************99966899*****************9977 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   0.4   1.8e-08   1.2e-05      25     147 ..      10     182 ..       2     192 .. 0.48

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 1.8e-08
      AAA_16  25 elvllsGesGvGKsslvrellralekdggiflrgkcdql.....esaipysalaqalareellrqlldeaesaeleawrekleeala............ 106
                 + v++sG+sG+GKs+l+++l+ ++ ++ + f   ++++      e +++y     ++++++ + +l de    e++++   + ++              
  EEA20796.1  10 RPVVISGPSGTGKSTLLKRLFAEFPDT-FGFSISHTTRAprageEDGREY-----YFTTKDDFLKLVDENGFIEHAQFGGNFYGTSVqavrniaskqri 102
                 669******************999998.6664333333312233333555.....33333334444444222222222222222222233333333333 PP

      AAA_16 107 ....................................avpelagaea...........srllellkrllallsrderplvlvlDdlqwa 147
                                                              +           +rl+++ ++l    +++++  ++v Ddl++a
  EEA20796.1 103 cildiemegvkqvkrtdlnarflflsppsleelerrL--------RgrgtetedslnKRLAQARNELEYSRQPGAHDKIVVNDDLEKA 182
                 3334445555555555555555555555333332320........2333333333335555555555534444444566666666665 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5   0.2   1.6e-07    0.0001       2     132 ..      12     156 ..      12     167 .. 0.62

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 1.6e-07
      AAA_33   2 vllvGlpGsGKstlaerllkklg...avllssdtlrrrlfgtdqqskt.................dytrvldrlyqilnelarkalsagrnvildatnl 80 
                 v++ G++G+GKstl++rl ++ +   ++ +s  t   r  ++d +                    + +++  ++y++  + +r  +s+ r +ild  + 
  EEA20796.1  12 VVISGPSGTGKSTLLKRLFAEFPdtfGFSISHTTRAPRAGEEDGREYYfttkddflklvdengfiEHAQFGGNFYGTSVQAVRNIASKQRICILDIEME 110
                 6789***************99999766666666633344433333222444444444555555445555556666666666666666666666665555 PP

      AAA_33  81 srrerarflklarrlgvpvrivvve.tdeetlkeRlakRaangddrsevpeea 132
                   ++ +r        + + r ++++ ++ e+l++Rl+ R  +++d+ +  +++
  EEA20796.1 111 GVKQVKR-------TDLNARFLFLSpPSLEELERRLRGRGTETEDSLNKRLAQ 156
                 5455444.......555555555551678999999999999988776665555 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.0   5.8e-08   3.7e-05       2      94 ..      12     116 ..      11     138 .. 0.74

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 5.8e-08
                 EEEEESTTSSHHHHHHHHHTS..TEEESSSTTSSSSEEEEEEE.......ETTEEEEEEECGGCSSHHHHHH.HHHHHHHHHHC..TSEEEEEEETTTT CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltge..kaivsdkpgtTrdinegrvk.......lkgkeielvDtpGliegaseek.glgkaflalee..adlillvvdasee 88 
                 v+i G + +GKStL+++l+ e       ++  tTr ++ g+ +       +k++ ++lvD  G+ie a+ +    g +++a+++  ++  + ++d++ e
  EEA20796.1  12 VVISGPSGTGKSTLLKRLFAEfpDTFGFSISHTTRAPRAGEEDgreyyftTKDDFLKLVDENGFIEHAQFGGnFYGTSVQAVRNiaSKQRICILDIEME 110
                 7999****************964445578999*****9997554444444556679*******998444444456666666666546888888888766 PP

                 CSHHHH CS
    MMR_HSR1  89 klkpld 94 
                 ++k+++
  EEA20796.1 111 GVKQVK 116
                 666654 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   0.3   1.7e-07   0.00011       1     125 [.      12     154 ..      12     160 .. 0.80
   2 ?   -0.6   0.0       2.8   1.8e+03      35      67 ..     159     189 ..     147     195 .. 0.56

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 1.7e-07
      AAA_18   1 IlltGtpGvGKttlakeLskrlgf.....................gvnlrdvakenglllevdpealdeskrldedkldklldaleenssaleegknlv 78 
                 ++++G++G+GK+tl k+L  +  f                     g+++ ++ k++ l l +++  + e+ ++  ++    ++a+++++s   ++  ++
  EEA20796.1  12 VVISGPSGTGKSTLLKRLFAE--FpdtfgfsishttraprageedGREYYFTTKDDFLKLVDENG-FIEHAQFGGNFYGTSVQAVRNIAS---KQRICI 104
                 78****************665..333356688887788888888888888888887777777777.888888888888888888888876...888889 PP

      AAA_18  79 idghlaeleseaakdikk..vvLtasp.eelleRlekRgyeeakikenee 125
                 +d  ++   + +++d++    +L  +  eel +Rl+ Rg+e+ +  +++ 
  EEA20796.1 105 LDIEMEGVKQVKRTDLNArfLFLSPPSlEELERRLRGRGTETEDSLNKRL 154
                 9999999999999999997777777779***********99987666655 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 2.8
      AAA_18  35 nglllevdpealdeskrldedkldklldaleen 67 
                 n+l+++++p      k+++ d l+k+ ++l+ +
  EEA20796.1 159 NELEYSRQPG--AHDKIVVNDDLEKAYTELRDW 189
                 3444455555..555555555555555555554 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0   8.4e-07   0.00054       7      30 ..      11      34 ..       6      60 .. 0.88
   2 ?   -1.6   0.0       4.8   3.1e+03      58      58 ..     140     140 ..     108     188 .. 0.61

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 8.4e-07
      AAA_22  7 ilvvtGesGtGKTtllrrlleqld 30
                 +v+ G+sGtGK+tll+rl+ +++
  EEA20796.1 11 PVVISGPSGTGKSTLLKRLFAEFP 34
                579*****************9985 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 4.8
      AAA_22  58 r 58 
                 r
  EEA20796.1 140 R 140
                 2 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.6   0.0     8e-07   0.00051       8      40 ..       6      38 ..       2     182 .. 0.81

  Alignments for each domain:
  == domain 1  score: 20.6 bits;  conditional E-value: 8e-07
                EETTSEEEEEESTTSSHHHHHHHHTTSS--SEE CS
                xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  8 lkegekvaivGenGaGKStLlkllagllkpteG 40
                +++ + v+i G++G+GKStLlk l  +  +t G
  EEA20796.1  6 VHKYRPVVISGPSGTGKSTLLKRLFAEFPDTFG 38
                66677799**************99998877665 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0   1.4e-06   0.00091       2      23 ..      12      38 ..      11     109 .. 0.74
   2 ?   -2.6   0.0       9.1   5.8e+03     131     144 ..     144     157 ..     114     172 .. 0.55

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 1.4e-06
      AAA_28  2 ivitGgestGKTtlleaLaar.....g 23
                +vi+G+++tGK+tll++L a+     g
  EEA20796.1 12 VVISGPSGTGKSTLLKRLFAEfpdtfG 38
                8*****************976444442 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 9.1
      AAA_28 131 leereaiderlrea 144
                  e    +++rl +a
  EEA20796.1 144 TETEDSLNKRLAQA 157
                 33333333333333 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   3.7e-06    0.0024     100     123 ..      10      41 ..       2      77 .. 0.66

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 3.7e-06
                  SEEEEECSTTSSHHHHHHHHCTT........- CS
  RsgA_GTPase 100 ktsvlvGqSGvGKStLinallpe........l 123
                  + +v+ G+SG GKStL+++l  e         
   EEA20796.1  10 RPVVISGPSGTGKSTLLKRLFAEfpdtfgfsI 41 
                  7789****************987555555443 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.2   2.7e-05     0.018       5      28 ..      12      38 ..       8     199 .. 0.67

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 2.7e-05
      AAA_24  5 iliyGpsgiGKTtlakel...gpkplf 28
                ++i Gpsg+GK+tl+k+l    p+++ 
  EEA20796.1 12 VVISGPSGTGKSTLLKRLfaeFPDTFG 38
                899*************99655444444 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0   5.1e-06    0.0033      29      61 ..       5      36 ..       1      49 [. 0.82

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 5.1e-06
       AAA_7 29 llknkkpvllvGptGtGKtviikdllkkldkek 61
                 +++ +pv++ Gp+GtGK++++k+l+ +++ ++
  EEA20796.1  5 SVHKYRPVVISGPSGTGKSTLLKRLFAEFP-DT 36
                678899******************999998.43 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   6.1e-06    0.0039       1      27 [.      12      50 ..      12     115 .. 0.80

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 6.1e-06
  RNA_helicase  1 iwlyGpsgeGKStlakeLakallkkl............k 27
                  ++++Gpsg+GKStl k+L +++ +++             
    EEA20796.1 12 VVISGPSGTGKSTLLKRLFAEFPDTFgfsishttraprA 50
                  689******************999994444444444441 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   9.3e-06    0.0059     124     155 ..       4      35 ..       1      42 [. 0.89

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 9.3e-06
       T2SSE 124 kavrerglilvsGgTgsGKttllyallkeink 155
                 ++v+++  +++sG+ g+GK+tll  l +e+++
  EEA20796.1   4 SSVHKYRPVVISGPSGTGKSTLLKRLFAEFPD 35 
                 57889999***************999998876 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   2.2e-05     0.014       2      27 ..       9      34 ..       8      86 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 2.2e-05
      AAA_14  2 rkilvitGaRrvGKTtllkqlikell 27
                ++++vi+G+  +GK+tllk+l+ e  
  EEA20796.1  9 YRPVVISGPSGTGKSTLLKRLFAEFP 34
                5799******************8765 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   2.5e-05     0.016       2     102 ..      12     106 ..      11     114 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 2.5e-05
                 EEEE--TTSSHHHHHHHHHHHH....GGGEEEEEEEEE-------EEEEEET.T--EEEEEETT---SSEETTEEE-HHHHHHHHHHHHHHHHHHH-EE CS
    NTPase_1   2 vfiTGppGvGKtTlvkkvlellkss.gvkvgGfyteevreggrrigFkivdlasgeegiLarveakreprvgkyvvdvesfeelalealrkalseadvi 99 
                 v+i+Gp+G+GK+Tl+k++  +  +  g++++   t +  + g+  g ++      + + L  v+++  +++ ++  +   f    ++a+r+  s++ ++
  EEA20796.1  12 VVISGPSGTGKSTLLKRLFAEFPDTfGFSIS--HTTRAPRAGEEDGREYYFT--TKDDFLKLVDENGFIEHAQFGGN---FYGTSVQAVRNIASKQRIC 103
                 79****************9999554344443..4555568888888888766..56667777777788888888887...5566677777777788888 PP

                 EE- CS
    NTPase_1 100 viD 102
                 ++D
  EEA20796.1 104 ILD 106
                 887 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   2.3e-05     0.015       1      22 [.      10      31 ..      10      36 .. 0.91

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 2.3e-05
                SCEEEEC-TTTCHHHHHHHHHH CS
       NACHT  1 rlvilqGeaGsGKTtLlqklal 22
                r+v++ G++G GK+tLl++l  
  EEA20796.1 10 RPVVISGPSGTGKSTLLKRLFA 31
                789****************975 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.1   2.3e-05     0.015      25      39 ..      12      26 ..       3      30 .. 0.86

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 2.3e-05
      AAA_29 25 tlltGpsGsGKSTll 39
                ++++GpsG+GKSTll
  EEA20796.1 12 VVISGPSGTGKSTLL 26
                689***********8 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   4.2e-05     0.027       1      32 [.      12      44 ..      12     186 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 4.2e-05
                EEEESSTTSSHHHHHHHHHHHHTHEE.EEEETT CS
         AAA  1 vllyGppGtGKTllakavakelgvef.leisgs 32
                v+++Gp GtGK++l k +  e+  +f ++is +
  EEA20796.1 12 VVISGPSGTGKSTLLKRLFAEFPDTFgFSISHT 44
                5789****************9855544555443 PP

>> DUF2075  Uncharacterized conserved protein (DUF2075)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   0.00018      0.12       4      26 ..      12      40 ..      10     177 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00018
     DUF2075  4 vlVtGvaGtGKtvvllnllael......e 26
                v+++G +GtGK+ +l +l+ae       +
  EEA20796.1 12 VVISGPSGTGKSTLLKRLFAEFpdtfgfS 40
                79******************995555540 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   0.0     3e-05     0.019      20      52 ..      11      44 ..       2     106 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 3e-05
      AAA_30 20 vavltGpAGtGKttalkalreaweaa.ggrvigl 52
                 +v+ Gp GtGK+t+lk l + + +  g+++   
  EEA20796.1 11 PVVISGPSGTGKSTLLKRLFAEFPDTfGFSISHT 44
                579**************99544444447666555 PP

>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.3   0.0   2.3e-05     0.014      46     106 ..      10      70 ..       1     109 [. 0.74

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 2.3e-05
       Rad17  46 riLLisGPsGCgkstvvkvLskelgiklrewlnpvslkepdnqksdfkg.ltekesrflsqi 106
                 r ++isGPsG gkst +k L  e+   +   +  ++ + p   ++d +   + +++ fl ++
  EEA20796.1  10 RPVVISGPSGTGKSTLLKRLFAEFPDTFGFSISHTT-RAPRAGEEDGREyYFTTKDDFLKLV 70 
                 5679****************9988777766666666.7777755555541466667776665 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   4.8e-05     0.031      19      44 ..       8      33 ..       3     186 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 4.8e-05
    ATPase_2 19 pneiyfiYGpegsGKtaLlkeiienl 44
                ++++++i Gp g GK++Llk++  + 
  EEA20796.1  8 KYRPVVISGPSGTGKSTLLKRLFAEF 33
                5789****************998776 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00022      0.14       2      22 ..      12      32 ..      11      45 .. 0.86
   2 ?   -0.8   0.0       2.1   1.4e+03      49      78 ..     141     183 ..     131     188 .. 0.65

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00022
                EEEE--SSSSHHHHHHHGGGG CS
       AAA_5  2 vlLvGppGtgKselaerlaaa 22
                v++ Gp+GtgKs+l +rl a 
  EEA20796.1 12 VVISGPSGTGKSTLLKRLFAE 32
                8999************99765 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 2.1
                 ........--------.............G-SEEEEESGGG-- CS
       AAA_5  49 ngttslvdsplvraar.............egeilvlDEverae 78 
                 +++t+ +ds  +r a+             + +i+v D++e+a 
  EEA20796.1 141 GRGTETEDSLNKRLAQarneleysrqpgaHDKIVVNDDLEKAY 183
                 5666666666666666666666777777777788888888775 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   0.00038      0.24      23      37 ..      13      27 ..      10      31 .. 0.90
   2 ?    0.5   0.0       1.1   7.3e+02     154     175 ..     131     153 ..      45     186 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00038
      AAA_23 23 lItGpNGaGKTTild 37
                +I+Gp G+GK+T+l 
  EEA20796.1 13 VISGPSGTGKSTLLK 27
                8************95 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 1.1
      AAA_23 154 rleelekeleel.edekkllekl 175
                  leele+ l+   +++++ l+k+
  EEA20796.1 131 SLEELERRLRGRgTETEDSLNKR 153
                 34444444333212222233332 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   0.00024      0.15       7      38 ..       6      37 ..       1      54 [. 0.80

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00024
      AAA_19  7 alkekvllvtaGpGtGKTrvlkhivallvelg 38
                 +k +++++ ++ GtGK+++lk   a++ ++ 
  EEA20796.1  6 VHKYRPVVISGPSGTGKSTLLKRLFAEFPDTF 37
                577899****************9998876655 PP

>> Adeno_IVa2  Adenovirus IVa2 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00022      0.14      91     108 ..      13      30 ..       3      34 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00022
  Adeno_IVa2  91 viyGPtGsGksqllrnli 108
                 vi+GP G+Gks ll+ l 
  EEA20796.1  13 VISGPSGTGKSTLLKRLF 30 
                 8*************9986 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0    0.0004      0.26       3      21 ..      12      30 ..      11      36 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.0004
                EEEEESTTCCHHHHHHHHH CS
        cobW  3 tvltGflGsGKTtLlnhll 21
                +v++G+ G+GK+tLl++l 
  EEA20796.1 12 VVISGPSGTGKSTLLKRLF 30
                69**************997 PP

>> dNK  Deoxynucleoside kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.0    0.0023       1.5       2      21 ..      13      32 ..      12      41 .. 0.86
   2 ?    0.4   0.1      0.79     5e+02     132     152 ..     131     151 ..     112     166 .. 0.82

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0023
                EEEESTTSSHHHHHHHHHCC CS
         dNK  2 vveGnIgaGKstlvklLskk 21
                v++G+ g GKstl+k+L  +
  EEA20796.1 13 VISGPSGTGKSTLLKRLFAE 32
                8**************98655 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.79
                 -HHHHHHHHHHCTTCCCTTS- CS
         dNK 132 sletclerikkRgreeekkie 152
                 sle++++r++ Rg e e   +
  EEA20796.1 131 SLEELERRLRGRGTETEDSLN 151
                 689999*******99998654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (200 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       738  (0.0411624); expected 358.6 (0.02)
Passed bias filter:                      689  (0.0384294); expected 358.6 (0.02)
Passed Vit filter:                       128  (0.00713927); expected 17.9 (0.001)
Passed Fwd filter:                        28  (0.00156172); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              28  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.42
# Mc/sec: 1445.22
//
Query:       EEA20797.1  [L=537]
Description: Golgi matrix protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.7e-08   34.0   0.1    1.7e-08   34.0   0.1    2.3  2  GRAB            GRIP-related Arf-binding domain
     0.0018   18.3  81.4       0.17   11.9  16.7    5.1  4  TPR_MLP1_2      TPR/MLP1/MLP2-like protein
      0.005   16.8  20.9      0.005   16.8  20.9    3.1  1  SIKE            SIKE family
  ------ inclusion threshold ------
      0.033   14.1  57.4       0.79    9.6  44.9    2.7  2  Apolipoprotein  Apolipoprotein A1/A4/E domain
      0.053   13.8  23.3       0.85    9.9   0.4    4.9  4  DUF948          Bacterial protein of unknown function (DUF948
      0.062   13.5   0.2      0.062   13.5   0.2    5.5  4  HALZ            Homeobox associated leucine zipper
      0.086   12.9  28.5       0.68   10.0   3.7    4.4  3  Baculo_PEP_C    Baculovirus polyhedron envelope protein, PEP,
        0.2   10.7  33.8      0.026   13.6   3.9    3.6  3  FH2             Formin Homology 2 Domain
       0.71    7.8  30.4      0.086   10.8   7.8    2.3  2  Prominin        Prominin
        1.7    8.7  30.5        2.1    8.4   5.2    4.2  5  DUF1664         Protein of unknown function (DUF1664)
        2.5    8.2  39.7       0.54   10.4   6.7    4.8  5  COG2            COG (conserved oligomeric Golgi) complex comp
        3.4    6.9  64.7      0.047   13.0  16.1    3.3  3  DUF4407         Domain of unknown function (DUF4407)
        3.9    7.5   9.5       0.78    9.8   0.4    3.7  3  TTRAP           Putative tranposon-transfer assisting protein
        4.2    6.8  74.6        0.7    9.3  14.7    3.9  3  Golgin_A5       Golgin subfamily A member 5
        4.2    7.1  67.1       0.97    9.2  16.3    3.6  3  FAM184          Family with sequence similarity 184, A and B
        4.4    8.0   6.2      3e+02    2.0   5.5    2.7  1  DUF3800         Protein of unknown function (DUF3800)
        6.8    6.1  78.9      0.083   12.4  18.1    3.1  3  HMMR_N          Hyaluronan mediated motility receptor N-termi
        8.9    5.1  73.4       0.21   10.4  32.6    3.5  4  Spc7            Spc7 kinetochore protein
        9.4    6.7  35.1        1.8    9.0   0.6    6.6  6  FlaC_arch       Flagella accessory protein C (FlaC)


Domain annotation for each model (and alignments):
>> GRAB  GRIP-related Arf-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.4       4.7   4.4e+03       1       7 [.      20      26 ..      20      26 .. 0.93
   2 !   34.0   0.1   1.8e-11   1.7e-08       1      19 []     408     426 ..     408     426 .. 0.97

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 4.7
        GRAB  1 sseenVD 7 
                sse nVD
  EEA20797.1 20 SSEQNVD 26
                79****9 PP

  == domain 2  score: 34.0 bits;  conditional E-value: 1.8e-11
        GRAB   1 sseenVDKrLISNLllsFL 19 
                 ++e+nVD+++++N+ll+FL
  EEA20797.1 408 KPEDNVDRHVVTNHLLHFL 426
                 79****************9 PP

>> TPR_MLP1_2  TPR/MLP1/MLP2-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.9  16.7   0.00018      0.17      10     115 ..      42     143 ..      33     146 .. 0.88
   2 !   11.4  16.3   0.00026      0.25      57     122 ..     131     196 ..     128     199 .. 0.93
   3 !    8.8  10.3    0.0017       1.6      53     113 ..     201     261 ..     197     266 .. 0.90
   4 !    6.9  19.6    0.0065       6.1      29     116 ..     279     367 ..     268     400 .. 0.52

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00018
  TPR_MLP1_2  10 ikslkeekeeaeaklqklqedlekqaeiakeaqqkYerelvkhaedvkelqalreelnelkaeiaelkaeaesakaeleeseesweeqkeelekelsel 108
                 +++lk+e e  e+++q +  + ++ a++a+e +++ e    ++a+d+k++++++  ++e +++  +l  +++s++ae+ e ++s+e+ + + e+e++ l
  EEA20797.1  42 KEELKDEPEGEENQAQGVNGQSKATADSATEKKNNDE----NNASDAKTITTTKPAASEDNSKFDDLVRDRDSLRAEVTELRKSLEQIQHKHEEEMEAL 136
                 4677777778888888888888888888888888655....589******************************************************* PP

  TPR_MLP1_2 109 ekriedl 115
                 ++++++ 
  EEA20797.1 137 QQKLNES 143
                 ***9985 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00026
  TPR_MLP1_2  57 kelqalreelnelkaeiaelkaeaesakaeleeseesweeqkeelekelselekriedlneqNklL 122
                 +e++al ++lne +++ ++++++ +++ + +++ ++++ e+ +e  +els++++rie+l++qN+ L
  EEA20797.1 131 EEMEALQQKLNESEDKKTQAETQFQKLLERVNTIKSQLGERLKEDAEELSQARSRIEELEDQNSAL 196
                 46778889*******************************************************998 PP

  == domain 3  score: 8.8 bits;  conditional E-value: 0.0017
  TPR_MLP1_2  53 aedvkelqalreelnelkaeiaelkaeaesakaeleeseesweeqkeelekelselekrie 113
                 +e++++++ l +++ e  +e+++l+++a+  ++++++++e++ eq++ ++ e +e+++ + 
  EEA20797.1 201 SENLTKIAGLEKDAREHSNELSNLRNRANLSQQNWQQEKEELIEQESYIRAEFEEAKQAMH 261
                 78889999999999999***********************************999999765 PP

  == domain 4  score: 6.9 bits;  conditional E-value: 0.0065
  TPR_MLP1_2  29 edlekqaeiakeaqqkYerelvkhaedvkelqalreelnelkaei.aelkaeaesakaeleeseesweeqkeelekelselekriedln 116
                 e+++  +e+++   + Y + +  ++++++++  l   l+e+++ + +el++ ++s  a+lee +e++++ +++ e+  ++l++  ++l+
  EEA20797.1 279 EKVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQEIQDARkQELRELVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQTELD 367
                 33334444444444444444444444444444444444444432213344444444444444444444444444444444444444443 PP

>> SIKE  SIKE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8  20.9   5.3e-06     0.005      24     175 ..      55     198 ..      38     201 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 5.3e-06
        SIKE  24 aAdsLleqaqalnkkiesmkqyqee.vkelneiakekprseLiagiqqenrqireLqqENreLrasleehqsaLelImsKYReqvskllkakkeekkea 121
                  A  +  q++a+ ++  ++k+  e+  ++ ++i+  kp        +++n ++ +L ++ + Lra + e ++ Le I  K+ e ++ l ++   +++e 
  EEA20797.1  55 QAQGVNGQSKATADSATEKKNNDENnASDAKTITTTKPA------ASEDNSKFDDLVRDRDSLRAEVTELRKSLEQIQHKHEEEMEALQQKL--NESED 145
                 444444455444444444443333335555556666654......466*************************************9986555..55555 PP

        SIKE 122 vlkkklseevesqeekieeMaaVmrkavevdeeesakeqeklaqLetENkeLRe 175
                  ++ +++++ +++ e+++ +++ + +  + d+ee ++ + ++++Le  N++L+ 
  EEA20797.1 146 KKT-QAETQFQKLLERVNTIKSQLGERLKEDAEELSQARSRIEELEDQNSALKA 198
                 555.679********************************************985 PP

>> Apolipoprotein  Apolipoprotein A1/A4/E domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7  32.2     0.054        51      34     189 ..     107     243 ..      64     262 .. 0.43
   2 ?    9.6  44.9   0.00083      0.79       3     186 ..     144     357 ..     144     381 .. 0.82

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.054
                     HHHHHHHHH...HHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCHHCCHHCHCCHCHHHHHHHHHHHHHHHHHHCHHHHH CS
  Apolipoprotein  34 eleelrarl...raeleevrarlepyrdevqeqlgqnleelrqrlapyteelrerlaadaeelqeqlavyaeelrerlerhvealkarlapyvee 125
                     + ++lra++   r+ le+   + e+ ++++q++l+++ e+ + + ++  ++l er++    +l e+l++ aeel                     
      EEA20797.1 107 DRDSLRAEVtelRKSLEQIQHKHEEEMEALQQKLNES-EDKKTQAETQFQKLLERVNTIKSQLGERLKEDAEEL--------------------- 179
                     3333333333334444444444444444444444433.333444444444444444444444444444444443..................... PP

                     HHHHHHHHHHHHHH-----..-----SSSHHHHHHHTS-T..TSHHHHHS--XXXXXXXXXXXXXX CS
  Apolipoprotein 126 lrqklaerleelkeslaphaeeveerlssrveelreklee..qaeelrerleanleelkaqlealv 189
                       q  ++r+eel+++  + ++ev e+l++ +   +++ e   ++++lr+r++  +++ +++ e+l+
      EEA20797.1 180 -SQ-ARSRIEELEDQNSALKAEVSENLTKIAGLEKDAREHsnELSNLRNRANLSQQNWQQEKEELI 243
                     .22.22222222222222222222222221111111111122333333333333333333322222 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00083
                     HHCCCCHHHHHCCHHHCHHCHHHHHHHHHHHHHHHHHHHH..HHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCHHCCHH CS
  Apolipoprotein   3 eesldelkayaeeleeqlaplaqelrdrlskeleelrarl..raeleevrarlepyrdevqeqlgqnleelrqrlapyteelrerlaadaeelqe 95 
                     e++  ++++++++l e+++ +  +l +rl +++eel+++    +ele+++++l++ ++e  ++++   ++ r++ ++ +++lr+r+++  ++ q+
      EEA20797.1 144 EDKKTQAETQFQKLLERVNTIKSQLGERLKEDAEELSQARsrIEELEDQNSALKAEVSENLTKIAGLEKDAREH-SNELSNLRNRANLSQQNWQQ 237
                     57788999*************99********9999977543338888888888888888888888877777777.77788888888888888888 PP

                     CHCCHCHH...........................HHHHHHHHHHHHHHHHCHHHHHHHH..HHHHHHHHHHH-----..-----SSSHHHHHHH CS
  Apolipoprotein  96 qlavyaee...........................lrerlerhvealkarlapyveelrq..klaerleelkeslaphaeeveerlssrveelre 161
                       ++  e+                           +re+l ++v +l ++l+ +++e  +  +      +  + l+ +++e++++  ++++el +
      EEA20797.1 238 EKEELIEQesyiraefeeakqamhnwevlameersIREGLTEKVNDLEEQLSSLRDEYNSavSDNNTQSNTIDGLQRALQEIQDARKQELRELVQ 332
                     88888888***************************************************733333344556677777777888888888888888 PP

                     TS-TTSHHHHHS--XXXXXXXXXXX CS
  Apolipoprotein 162 kleeqaeelrerleanleelkaqle 186
                     + ++q+eelre+l+++ ++ ++  +
      EEA20797.1 333 SSDAQLEELREKLQQVEKRAEEANT 357
                     8888888888888887777776544 PP

>> DUF948  Bacterial protein of unknown function (DUF948)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   3.6      0.14   1.3e+02      24      70 ..     111     157 ..      84     174 .. 0.63
   2 ?    8.8   0.3     0.002       1.9      26      73 ..     177     224 ..     168     237 .. 0.87
   3 ?    9.9   0.4    0.0009      0.85      29      82 ..     275     321 ..     264     325 .. 0.72
   4 ?    4.0   1.2     0.062        58      34      72 ..     337     371 ..     320     388 .. 0.52

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.14
      DUF948  24 lkktldeaaatieelekqvdpilkevedllakvnelledvneklekv 70 
                 l+  ++e+++++e+++++ ++ ++ +++ l+++++   + + + +k+
  EEA20797.1 111 LRAEVTELRKSLEQIQHKHEEEMEALQQKLNESEDKKTQAETQFQKL 157
                 55667777777777775555555555555555555333333333332 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.002
      DUF948  26 ktldeaaatieelekqvdpilkevedllakvnelledvneklekvdpl 73 
                 + l++a+++ieele+q  ++  ev + l+k+  l +d +e+++++ +l
  EEA20797.1 177 EELSQARSRIEELEDQNSALKAEVSENLTKIAGLEKDAREHSNELSNL 224
                 67899*********************************9999998876 PP

  == domain 3  score: 9.9 bits;  conditional E-value: 0.0009
      DUF948  29 deaaatieelekqvdpilkevedllakvnelledvneklekvdplteavadlge 82 
                 + +++ +++le+q+ ++ +e + +++  n+       +++++d l  a++++ +
  EEA20797.1 275 EGLTEKVNDLEEQLSSLRDEYNSAVSDNNT-------QSNTIDGLQRALQEIQD 321
                 445666677777777777777777776666.......99999999999999876 PP

  == domain 4  score: 4.0 bits;  conditional E-value: 0.062
      DUF948  34 tieelekqvdpilkevedllakvnelledvneklekvdp 72 
                 ++ee    +++ l++ve+  +++n+ l++ + +l+++ p
  EEA20797.1 337 QLEE----LREKLQQVEKRAEEANTDLKQAQTELDRLLP 371
                 2222....2333344444444444444445555555555 PP

>> HALZ  Homeobox associated leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.2   6.6e-05     0.062      19      42 ..      99     122 ..      98     123 .. 0.91
   2 ?    5.8   1.2     0.018        17      19      37 ..     184     202 ..     170     205 .. 0.89
   3 ?   -0.8   0.1       1.9   1.8e+03      30      39 ..     283     292 ..     274     303 .. 0.60
   4 ?    0.6   0.8       0.7   6.6e+02      33      43 .]     336     346 ..     324     346 .. 0.91

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 6.6e-05
        HALZ  19 sdydsLkkenekLkaelqeLkekl 42 
                 s++d L +++++L+ae+ eL++ l
  EEA20797.1  99 SKFDDLVRDRDSLRAEVTELRKSL 122
                 78******************9876 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.018
        HALZ  19 sdydsLkkenekLkaelqe 37 
                 s+ + L+++n +Lkae+ e
  EEA20797.1 184 SRIEELEDQNSALKAEVSE 202
                 7899************976 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 1.9
        HALZ  30 kLkaelqeLk 39 
                  L+ +l +L+
  EEA20797.1 283 DLEEQLSSLR 292
                 3444444444 PP

  == domain 4  score: 0.6 bits;  conditional E-value: 0.7
        HALZ  33 aelqeLkeklq 43 
                 a+l+eL+eklq
  EEA20797.1 336 AQLEELREKLQ 346
                 79*******97 PP

>> Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   8.8    0.0097       9.2      25      95 ..     111     180 ..     103     245 .. 0.60
   2 ?   10.0   3.7   0.00072      0.68      32      90 ..     273     330 ..     266     343 .. 0.81
   3 ?    3.9   2.0     0.052        49      34      87 ..     346     401 ..     331     406 .. 0.62

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0097
  Baculo_PEP_C  25 irlqnvqilaqlatlldaietqLnalsedlksllaeldtrldtlltnLtdalnalqdtlrneLtnlnsilt 95 
                   +r+  +++   l+++  + e++++al+++l++ +++ +t+ +t++++L + +n+++ +l ++L+    +l+
    EEA20797.1 111 LRAEVTELRKSLEQIQHKHEEEMEALQQKLNE-SEDKKTQAETQFQKLLERVNTIKSQLGERLKEDAEELS 180
                   55555666666666666666666666666666.55666666666666666666666444433333222222 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00072
  Baculo_PEP_C  32 ilaqlatlldaietqLnalsedlksllaeldtrldtlltnLtdalnalqdtlrneLtnl 90 
                   i   l++ ++++e+qL++l ++ +s++++ +t+ +++++ L++al+++qd+ ++eL  l
    EEA20797.1 273 IREGLTEKVNDLEEQLSSLRDEYNSAVSDNNTQ-SNTIDGLQRALQEIQDARKQELREL 330
                   666799*********************998887.566899*********7777776543 PP

  == domain 3  score: 3.9 bits;  conditional E-value: 0.052
  Baculo_PEP_C  34 aqlatlldaietqLnalsedlksllaeldt...rldtlltnLtdalnalqdtlrneL 87 
                    q+++  ++ +t L++ +++l +ll+ +++   + + l+ +L +   +l+d l+++L
    EEA20797.1 346 QQVEKRAEEANTDLKQAQTELDRLLP-FEKevkEKNLLIGKLRHEAVTLNDHLTKAL 401
                   45566666666666666666666666.333344445577888888889998888877 PP

>> FH2  Formin Homology 2 Domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   9.7     0.048        45     278     351 ..     101     171 ..      84     205 .. 0.65
   2 ?    4.9   5.3     0.013        12     261     345 ..     215     299 ..     196     308 .. 0.83
   3 ?   13.6   3.9   2.8e-05     0.026     254     368 ..     313     426 ..     303     428 .. 0.64

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.048
                 HHHHHHHHHHHHHHHHHHHHHHHHCCTTSSTT-THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-- CS
         FH2 278 leslekevkklekglkklekelessekkeepsdkflevlkeflkeaeeklkkleeelkeakelvkelveYfged 351
                 +++l+ + + l+ ++ +l+k+le+ ++   ++++ +e+l++ l+e+e+k  + e++ ++++e+v+++   +ge+
  EEA20797.1 101 FDDLVRDRDSLRAEVTELRKSLEQIQH---KHEEEMEALQQKLNESEDKKTQAETQFQKLLERVNTIKSQLGER 171
                 667777777777777777777777766...44444566666666666666666666666666666655544443 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.013
                 GGHHHHTTTHHHCCTS-HHHHHHHHHHHHHHHHHHHHHHHHCCTTSSTT-THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
         FH2 261 ldfsseLknvkkaakvnleslekevkklekglkklekelessekkeepsdkflevlkeflkeaeeklkkleeelkeakelvkelv 345
                  + s+eL+n++  a+++ ++ ++e ++l ++ + ++ e+e+ +++ ++++ +    +++ +  +ek+++lee+l++++++++++v
  EEA20797.1 215 REHSNELSNLRNRANLSQQNWQQEKEELIEQESYIRAEFEEAKQAMHNWEVLAMEERSIREGLTEKVNDLEEQLSSLRDEYNSAV 299
                 55689***************************************66666666666666666667888888888888888887765 PP

  == domain 3  score: 13.6 bits;  conditional E-value: 2.8e-05
                 HTTSGGGGGHH.HHTTTHHHCCTS-HHHHHHHHHHHHHHHHHHHHHHHHCCTTSSTT-THHHHHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHT CS
         FH2 254 reklpevldfs.seLknvkkaakvnleslekevkklekglkklekelessekkeepsdkflevlkeflkeaeek...lkkleeelkeakelvkelveYf 348
                 +++l+e++d   +eL+++ +++  +le+l+++++++ek+ ++++++l++ ++        l+ l +f ke +ek   + kl+ e  ++++ ++++++++
  EEA20797.1 313 QRALQEIQDARkQELRELVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQT-------ELDRLLPFEKEVKEKnllIGKLRHEAVTLNDHLTKALRFL 404
                 3455555555545666666666666666666666666666666666666665.......6667777777777763336677777777777888888888 PP

                 ..T--TTCCHHHHHHHHHHHHH CS
         FH2 349 ..gedkkevspeeffkilreFl 368
                   g+ +++v +  +++ l +Fl
  EEA20797.1 405 krGKPEDNVDRHVVTNHLLHFL 426
                 7655555888888888888887 PP

>> Prominin  Prominin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7  16.6     0.099        93     619     714 ..     120     220 ..      63     260 .. 0.73
   2 ?   10.8   7.8   9.1e-05     0.086     277     378 ..     271     369 ..     236     381 .. 0.84

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.099
    Prominin 619 kkltkvnletlaekleelanelsngk...knlkqslkneaqdlraiqqelvlplessvkklkksvkklde...ensdlqesikkllaaveraenflkkn 711
                 k+l +++  + +e++e+l+++l++++   +++++++++  + +++i+++l ++l++ +++l +   +++e   +ns l++++++ l+++  +e+  +++
  EEA20797.1 120 KSLEQIQH-KHEEEMEALQQKLNESEdkkTQAETQFQKLLERVNTIKSQLGERLKEDAEELSQARSRIEEledQNSALKAEVSENLTKIAGLEKDAREH 217
                 44333332.334455555555555555557889999999999999999999999999999887766666666599999999999999999888766665 PP

    Prominin 712 gse 714
                  +e
  EEA20797.1 218 SNE 220
                 554 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 9.1e-05
    Prominin 277 rgvkrdlnqalsnlCqseeCskilssleiekldtskcldqlpnvdevlealeevletnlssivkeglarlneipekvknqtaevvpdlkkalakgreqi 375
                 r++++ l++ +++l  +e+ s+++++++    d++++ ++++ +++ l++++++ +++l ++v+++ a+l+e++ek++ q+++  ++   +l+++++++
  EEA20797.1 271 RSIREGLTEKVNDL--EEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQEIQDARKQELRELVQSSDAQLEELREKLQ-QVEKRAEEANTDLKQAQTEL 366
                 55666666666662..35788899999999999*******************************************96.78888999999999999988 PP

    Prominin 376 kkl 378
                 ++l
  EEA20797.1 367 DRL 369
                 765 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   8.3    0.0027       2.5      36     113 ..     108     186 ..      99     198 .. 0.76
   2 ?    5.2   2.0     0.021        20      51     104 ..     155     208 ..     151     233 .. 0.42
   3 ?    0.7   1.7      0.54   5.1e+02      63     121 ..     227     285 ..     194     293 .. 0.50
   4 ?    1.2   0.8      0.38   3.6e+02      82     105 ..     274     297 ..     240     320 .. 0.59
   5 ?    8.4   5.2    0.0022       2.1      49     106 ..     311     369 ..     299     379 .. 0.80

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0027
     DUF1664  36 krslsdavesvskqleqvseslaatkrhLssridrvdkkldeqkeiskeikeevtevredl.seigedvesvkeavegl 113
                 + sl+  v+++ k+leq++++ ++  + L++++++ ++k  + +   +++ e v++++++l ++++ed e++++a + +
  EEA20797.1 108 RDSLRAEVTELRKSLEQIQHKHEEEMEALQQKLNESEDKKTQAETQFQKLLERVNTIKSQLgERLKEDAEELSQARSRI 186
                 6788889999999999999999999999999999988888888888888888899998887456777777776654333 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.021
     DUF1664  51 eqvseslaatkrhLssridrvdkkldeqkeiskeikeevtevredlseigedve 104
                 +++ e +++ k +L +r+++  ++l +    ++e++++ ++++ ++se  +++ 
  EEA20797.1 155 QKLLERVNTIKSQLGERLKEDAEELSQARSRIEELEDQNSALKAEVSENLTKIA 208
                 444444444444444444443333333333333333333333333332222222 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 0.54
     DUF1664  63 hLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeaveglesklerie 121
                 + +   ++ +++ +e +e  + i++e +e+++ +++ +    + +++ egl +k++++e
  EEA20797.1 227 RANLSQQNWQQEKEELIEQESYIRAEFEEAKQAMHNWEVLAMEERSIREGLTEKVNDLE 285
                 33333334444445555555555555555555555554444444444444555555444 PP

  == domain 4  score: 1.2 bits;  conditional E-value: 0.38
     DUF1664  82 skeikeevtevredlseigedves 105
                  + ++e+v++++e+ls+++++ +s
  EEA20797.1 274 REGLTEKVNDLEEQLSSLRDEYNS 297
                 444444555555555554444433 PP

  == domain 5  score: 8.4 bits;  conditional E-value: 0.0022
     DUF1664  49 qleqvseslaat.krhLssridrvdkkldeqkeiskeikeevtevredlseigedvesv 106
                  l++  ++++++ k++L + +++ d++l+e  e  +++++  +e++ dl++ +++++ +
  EEA20797.1 311 GLQRALQEIQDArKQELRELVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQTELDRL 369
                 3455556666542789**********************************999998765 PP

>> COG2  COG (conserved oligomeric Golgi) complex component, COG2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   6.7   0.00057      0.54      69     129 ..     106     168 ..      99     172 .. 0.85
   2 ?    4.7   2.3     0.032        30      63     111 ..     178     226 ..     167     235 .. 0.51
   3 ?    0.9   1.7      0.46   4.4e+02      66     113 ..     209     257 ..     198     275 .. 0.51
   4 ?    7.9   1.3    0.0032         3      66     121 ..     276     332 ..     273     336 .. 0.89
   5 ?    5.2   3.7     0.023        22      66     113 ..     333     380 ..     328     401 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00057
        COG2  69 eeleevesplaaarkkvesvreklsereeeveskleeakeleekr..ellklllkldevvekl 129
                 ++ + ++ +++++rk +e++++k +e +e++++kl+e ++ + +   ++ kll ++++  ++l
  EEA20797.1 106 RDRDSLRAEVTELRKSLEQIQHKHEEEMEALQQKLNESEDKKTQAetQFQKLLERVNTIKSQL 168
                 5678899*****************************998877666669999999998887777 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.032
        COG2  63 hLvglqeeleevesplaaarkkvesvreklsereeeveskleeakelee 111
                 +L   ++++ee+e + +a++ +v+++  k++  e++ ++  +e ++l++
  EEA20797.1 178 ELSQARSRIEELEDQNSALKAEVSENLTKIAGLEKDAREHSNELSNLRN 226
                 3344444455555555555555555555555555555555555555444 PP

  == domain 3  score: 0.9 bits;  conditional E-value: 0.46
        COG2  66 glqeeleevesplaaarkkvesvreklsereee.veskleeakeleekr 113
                 gl+++ +e + +l+++r++ +  +++ ++ +ee +e++   ++e ee++
  EEA20797.1 209 GLEKDAREHSNELSNLRNRANLSQQNWQQEKEElIEQESYIRAEFEEAK 257
                 5566666666666666665555555554443331333333333333333 PP

  == domain 4  score: 7.9 bits;  conditional E-value: 0.0032
        COG2  66 glqeeleevesplaaarkkvesvreklsereeeveskleeakeleekr.ellklllk 121
                 gl e+++ +e +l+++r++ +s+++  + +++++++  ++ +e++++r + l+ l++
  EEA20797.1 276 GLTEKVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQEIQDARkQELRELVQ 332
                 8999*****************************************999766666655 PP

  == domain 5  score: 5.2 bits;  conditional E-value: 0.023
        COG2  66 glqeeleevesplaaarkkvesvreklsereeeveskleeakeleekr 113
                 + +++lee++ +l+++ k+ e+++  l+++++e++  l   ke++ek+
  EEA20797.1 333 SSDAQLEELREKLQQVEKRAEEANTDLKQAQTELDRLLPFEKEVKEKN 380
                 567899999999999999999999999999999999988888888876 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0  26.0      0.11   1.1e+02     130     250 ..      28     164 ..       4     171 .. 0.73
   2 ?   13.0  16.1     5e-05     0.047     108     243 ..     164     312 ..     161     317 .. 0.73
   3 ?    6.2  20.0    0.0058       5.5     135     241 ..     267     367 ..     228     371 .. 0.67

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.11
     DUF4407 130 a....................ltaelaeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaakekkaqldaaqaelaelkaklda 208
                                       + e ++++  + + +a+ d+a ++ ++ +++a +  +   +t+ ++   +   ++   ++ d ++ae++el+++   
  EEA20797.1  28 GkaadnetqndavvkeelkdePEGEENQAQGVNGQSKATADSATEKKNNDENNASDAKTI--TTTKPAASEDNSKFDDLVRDRDSLRAEVTELRKS--L 122
                 122222222233333343334666666666666688888888888888888888887776..6666788889999999999999999999999999..9 PP

     DUF4407 209 tarlaalraelaeleaerakeraasqaaaaaddGllarleal 250
                 ++ + ++++e++ l+++++++++++++a+ +++ ll+r + +
  EEA20797.1 123 EQIQHKHEEEMEALQQKLNESEDKKTQAETQFQKLLERVNTI 164
                 9999999*******************************9876 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 5e-05
     DUF4407 108 IdaelaeeqqeeakelkeqlaaaltaelaeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaake....kkaqldaaqaelael 202
                 I+++l e+ +e+a+el     ++++++++ele+q++al+ae+++  ++++ l+++a+++ + + ++  ++ +   ++ ++      +q   ++ae +e+
  EEA20797.1 164 IKSQLGERLKEDAEEL-----SQARSRIEELEDQNSALKAEVSENLTKIAGLEKDAREHSN-ELSNLRNRANLSQQNWQQekeeLIEQESYIRAEFEEA 256
                 6666666666666666.....55899******************************96655.4544444444444444442112222223334444444 PP

     DUF4407 203 kakld...............atarlaalraelaeleaerakeraasqaaaaaddGl 243
                 k+ +                 t+++++l+++l++l++e+++++++++++++  dGl
  EEA20797.1 257 KQAMHnwevlameersiregLTEKVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGL 312
                 44444888888899999**********************************99998 PP

  == domain 3  score: 6.2 bits;  conditional E-value: 0.0058
     DUF4407 135 laeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaakekkaqldaaqaelaelkakldatarlaalraelaeleaerakeraas 233
                   e+++ ++ l ++++ +e++l+ lr+e+++ ++ + +t+ + + G     ++ ++  da+++el el ++  ++a+l++lr++l+++e+++++++++ 
  EEA20797.1 267 AMEERSIREGLTEKVNDLEEQLSSLRDEYNSAVSDN-NTQSNTIDGL---QRALQEIQDARKQELRELVQS--SDAQLEELREKLQQVEKRAEEANTDL 359
                 234445555999999999999999999999999964.4444445555...666777888888899999999..99999999999999999999888888 PP

     DUF4407 234 qaaaaadd 241
                 ++a+ + d
  EEA20797.1 360 KQAQTELD 367
                 88777665 PP

>> TTRAP  Putative tranposon-transfer assisting protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.5      0.33   3.2e+02      21      42 ..     112     139 ..     105     147 .. 0.66
   2 ?   -2.7   0.1       6.6   6.2e+03      19      35 ..     156     177 ..     153     191 .. 0.64
   3 ?    9.8   0.4   0.00082      0.78      14      52 ..     302     343 ..     292     345 .. 0.87

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.33
                 HHHHHHSTTTS.......-HHHHHHHHH CS
       TTRAP  21 ieelkaalkyl......eddelreLaes 42 
                  +e ++ +k l       ++e+ +L ++
  EEA20797.1 112 RAEVTELRKSLeqiqhkHEEEMEALQQK 139
                 4444444444444499889999999764 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 6.6
                 HHHHHHHHSTTTS......-HH CS
       TTRAP  19 elieelkaalkyl.....edde 35 
                 +l+e+ +++ ++l     ed+e
  EEA20797.1 156 KLLERVNTIKSQLgerlkEDAE 177
                 5677777777777555544443 PP

  == domain 3  score: 9.8 bits;  conditional E-value: 0.00082
                 -SHHHHHHHHHHHSTTTS....-HHHHHHHHHHHHHHTT--H CS
       TTRAP  14 egtRkelieelkaalkyl...eddelreLaestlaKLkaltD 52 
                 ++t +++i+ l+ al+ +   + +elreL++s  a L++l++
  EEA20797.1 302 NNTQSNTIDGLQRALQEIqdaRKQELRELVQSSDAQLEELRE 343
                 56999*************887789*******99999998887 PP

>> Golgin_A5  Golgin subfamily A member 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6  24.4    0.0012       1.1      40     158 ..      85     203 ..      62     208 .. 0.82
   2 ?    9.3  14.7   0.00075       0.7      36     135 ..     201     300 ..     193     308 .. 0.86
   3 ?    7.5  12.8    0.0026       2.4      70     143 ..     312     388 ..     297     408 .. 0.47

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0012
   Golgin_A5  40 esstalsaeldelkqerdllreelqklnqqieqlrtelqdleaqqqaeaeslreqlqeleeqleeerkakeeveaelerlkeelryleeelvrskatlq 138
                 ++ t+++ + +e +++ d l  +  +l+ ++ +lr+ l+++++++++e+e l+++l+e+e++ ++ + + +++ + ++ +k +l    +e  ++ ++ +
  EEA20797.1  85 KTITTTKPAASEDNSKFDDLVRDRDSLRAEVTELRKSLEQIQHKHEEEMEALQQKLNESEDKKTQAETQFQKLLERVNTIKSQLGERLKEDAEELSQAR 183
                 23333444455555555666677889999**********************************999999999************99999999999**** PP

   Golgin_A5 139 srikdrekeieklrnqlttk 158
                 sri++ e++ + l+++++ +
  EEA20797.1 184 SRIEELEDQNSALKAEVSEN 203
                 ******99999999988765 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.00075
   Golgin_A5  36 eeglesstalsaeldelkqerdllreelqklnqqieqlrtelqdleaqqqaeaeslreqlqeleeqleeerkakeeveaelerlkeelryleeelvrsk 134
                 +e+l     l+++  e ++e   lr+  + ++q+ +q + el + e+   ae+e++++ +++ e    eer+ +e + ++++ l+e+l++l++e   + 
  EEA20797.1 201 SENLTKIAGLEKDAREHSNELSNLRNRANLSQQNWQQEKEELIEQESYIRAEFEEAKQAMHNWEVLAMEERSIREGLTEKVNDLEEQLSSLRDEYNSAV 299
                 455555566778888889999999**********************************************************************87655 PP

   Golgin_A5 135 a 135
                 +
  EEA20797.1 300 S 300
                 4 PP

  == domain 3  score: 7.5 bits;  conditional E-value: 0.0026
   Golgin_A5  70 ieqlrtelqdleaqqqae.aeslreqlqeleeqleeerkakeeveaelerlkeelryle..eelvrskatlqsrikd 143
                 +++  +e+qd  +q+  e ++s+  ql+el+e+l++ +k+ ee++++l++ + el++l   e  v++k+ l +++++
  EEA20797.1 312 LQRALQEIQDARKQELRElVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQTELDRLLpfEKEVKEKNLLIGKLRH 388
                 22333333333333333322333445555555555555555555555555555555543223334444444444444 PP

>> FAM184  Family with sequence similarity 184, A and B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3  25.8      0.13   1.2e+02      66     204 ..      59     198 ..      38     204 .. 0.66
   2 ?    8.3  11.4    0.0019       1.8     115     185 ..     185     264 ..     183     271 .. 0.87
   3 ?    9.2  16.3     0.001      0.97      86     184 ..     269     369 ..     264     381 .. 0.77

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.13
      FAM184  66 ekekrqalaefeqykrrveerelkleaehsqkvvelsreveevkrkFeeklrqfaqlqeqleqekekaLeelrkkhreeveeLlkeqeaqsekllkeqe 164
                 ++ + +a a+  + k++ +e+++++     +++++ +    e   kF++ +r+  +l++++  e +k+Le++++kh+ee+e L+++ ++ + k ++ + 
  EEA20797.1  59 VNGQSKATADSATEKKNNDENNASDA----KTITTTKPAASEDNSKFDDLVRDRDSLRAEV-TELRKSLEQIQHKHEEEMEALQQKLNESEDKKTQAET 152
                 55556666666666666555555554....3455555666666788999999988888887.588999***************9988766555444443 PP

      FAM184 165 kl......eekhkaev.eklkeeveelekekkklveeyEeklakqka 204
                 +        +++k ++ e+lke++eel++ +++++ e E++ +++ka
  EEA20797.1 153 QFqkllerVNTIKSQLgERLKEDAEELSQARSRIE-ELEDQNSALKA 198
                 33122444334455554678888999999999975.56666555555 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.0019
      FAM184 115 klrqfaqlqeqleqekeka......LeelrkkhreeveeLlkeqeaqsekllkeqekl...eekhkaeveklkeeveele 185
                 +++++++++++l++e +++      Le+  ++h++e+++L+++ +  ++++++e+e+l   e+ ++ae e++k++++++e
  EEA20797.1 185 RIEELEDQNSALKAEVSENltkiagLEKDAREHSNELSNLRNRANLSQQNWQQEKEELieqESYIRAEFEEAKQAMHNWE 264
                 7889999999999877777666677999999***************************9877789**********99987 PP

  == domain 3  score: 9.2 bits;  conditional E-value: 0.001
      FAM184  86 relkleaehsqkvvelsreveevkrkFeeklrqfaqlqeqleqekekaLeelrkkhreeveeLlkeqeaqsekllkeqekl...eekhkaeveklkeev 181
                 +e + ++  ++kv  l++++  ++ +++ ++++ +  q++     ++aL+e++ + ++e+ eL+++++aq e+l +  +++   +e+ ++++++++ e+
  EEA20797.1 269 EERSIREGLTEKVNDLEEQLSSLRDEYNSAVSDNNT-QSNTIDGLQRALQEIQDARKQELRELVQSSDAQLEELREKLQQVekrAEEANTDLKQAQTEL 366
                 5667788889*********************99655.5556667899*************************999988888333445555566655555 PP

      FAM184 182 eel 184
                 ++l
  EEA20797.1 367 DRL 369
                 555 PP

>> DUF3800  Protein of unknown function (DUF3800)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   5.5      0.32     3e+02      12      12 ..     256     256 ..      61     442 .. 0.60

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.32
     DUF3800  12 l 12 
                 +
  EEA20797.1 256 A 256
                 1 PP

>> HMMR_N  Hyaluronan mediated motility receptor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5  16.7      0.17   1.6e+02      22     140 ..       7     126 ..       4     130 .. 0.88
   2 ?    2.1  32.4      0.11   1.1e+02     184     321 ..     126     260 ..     119     270 .. 0.56
   3 ?   12.4  18.1   8.8e-05     0.083     202     309 ..     278     380 ..     264     400 .. 0.82

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.17
      HMMR_N  22 vsFeksqRfkkqkesqqnlssskdasttaaarkvsvlelk.kaksqkkdkskltkekkkqkeLEkeiRsLvqergeqdkrlqaleeelkkveakLlaav 119
                  s+ ks++ kk+++s+qn++s k a   +++  v ++elk +++ + ++++++  ++k       e ++  ++++   k +   +  +   ++k   +v
  EEA20797.1   7 YSSAKSKKNKKNQSSEQNVDSGKAADNETQNDAVVKEELKdEPEGEENQAQGVNGQSKATADSATEKKNNDENNASDAKTITTTKPAASEDNSKFDDLV 105
                 5899********************999888888877777725689999999999999999988888888889999999********************* PP

      HMMR_N 120 rektslsanvasLekqlaelk 140
                 r++ sl a v+ L k l  ++
  EEA20797.1 106 RDRDSLRAEVTELRKSLEQIQ 126
                 ***************998776 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.11
      HMMR_N 184 QedmeaklqvtqknLeeskakvaqLkeklvslekekieekseteklleyieels.nvseqlekykldiaqleellkekndeiesLkssLeekeqelskq 281
                 Q++                +++ +L++kl ++e++k++  ++ +klle ++ ++ ++ e+l    +++ q+++ ++e +d+ + Lk +++e+ +++   
  EEA20797.1 126 QHK--------------HEEEMEALQQKLNESEDKKTQAETQFQKLLERVNTIKsQLGERLKEDAEELSQARSRIEELEDQNSALKAEVSENLTKIAGL 210
                 333..............4556666777777777777666667777777666664145566666666666666677777777777777776666655444 PP

      HMMR_N 282 vkdlnekcklle..............kekeelvreeeekeqtlsaEleelkekl 321
                  kd+ e+ ++l               +eke    e  e+e+ + aE ee k+++
  EEA20797.1 211 EKDAREHSNELSnlrnranlsqqnwqQEKE----ELIEQESYIRAEFEEAKQAM 260
                 444444444444333444443211114444....33456667777777777766 PP

  == domain 3  score: 12.4 bits;  conditional E-value: 8.8e-05
      HMMR_N 202 kakvaqLkeklvslekekieekseteklleyieelsnvseqlekykldiaqleellkekndeiesLkssLeekeqelskqvkdlnekckllekekeelv 300
                  +kv  L+e+l+sl +e +   s+++ + + i+ l+ + +++     + ++l+el+++ + ++e+L+++L++ e+    +++++n+ +k+ ++e++ l+
  EEA20797.1 278 TEKVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQEI--QDARKQELRELVQSSDAQLEELREKLQQVEK----RAEEANTDLKQAQTELDRLL 370
                 689**************************************9..5666789**************9999998766....88888888888888888776 PP

      HMMR_N 301 r.eeeekeqt 309
                   e+e+ke++
  EEA20797.1 371 PfEKEVKEKN 380
                 4244444444 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.8       2.2   2.1e+03     225     254 ..      10      39 ..       4      54 .. 0.44
   2 ?    4.4  19.9     0.016        15     180     284 ..      66     170 ..      38     174 .. 0.88
   3 ?   10.4  32.6   0.00022      0.21     138     293 ..     116     272 ..     115     274 .. 0.90
   4 ?    8.6  20.8   0.00079      0.75     139     234 ..     272     371 ..     255     383 .. 0.74

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 2.2
        Spc7 225 lqeqleeleekieelkeqkseleeeiaeae 254
                  ++++++++++ e+  ++ + + +e+++  
  EEA20797.1  10 AKSKKNKKNQSSEQNVDSGKAADNETQNDA 39 
                 333333333333333333333333333333 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.016
        Spc7 180 eeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaervleeckgwsesevsrlkeevkal 278
                 ++  +++++ ++e +++d + + +++ + +e +++ + + ++ ++l+++++el++++e+++ + +e +e+++++ +  e +k   e++ ++l e+v+++
  EEA20797.1  66 TADSATEKKNNDENNASDAKTITTTKPAASEDNSKFDDLVRDRDSLRAEVTELRKSLEQIQHKHEEEMEALQQKLNESEDKKTQAETQFQKLLERVNTI 164
                 4445566777888899*********************************************************************************** PP

        Spc7 279 eeltgw 284
                 ++++g 
  EEA20797.1 165 KSQLGE 170
                 999875 PP

  == domain 3  score: 10.4 bits;  conditional E-value: 0.00022
        Spc7 138 egLkegleenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleeki 236
                  +L+++le++  + ee+ e L+++ +e ++ + + e+++++l e++++++++  e  + d eeL ++r++++el+ + +++k+e++e  ++++ le++ 
  EEA20797.1 116 TELRKSLEQIQHKHEEEMEALQQKLNESEDKKTQAETQFQKLLERVNTIKSQLGERLKEDAEELSQARSRIEELEDQNSALKAEVSENLTKIAGLEKDA 214
                 6899***********************************************9999999***************************************** PP

        Spc7 237 eelkeqkseleeeiaeaervleeckgwsesevsrlkeevkal.eeltgwkivslsgst 293
                  e +++ s+l+++ + +++  +++k+   ++ s +++e+++  +  ++w+++ +++ +
  EEA20797.1 215 REHSNELSNLRNRANLSQQNWQQEKEELIEQESYIRAEFEEAkQAMHNWEVLAMEERS 272
                 ***********99998888777777777666677888887651567999999888765 PP

  == domain 4  score: 8.6 bits;  conditional E-value: 0.00079
        Spc7 139 gLkegleenlegleedkelLekqeeeldellpeleeekaeleeeleklqe....aaeelesidkeeLeelreelaelkaeieekkkelaelqeqleele 233
                 +++egl+e++++lee+ + L ++ + + +  +  ++  + l++ l+++q+    + +el ++  ++Leelre+l+++++  ee +++l++ q++l++l 
  EEA20797.1 272 SIREGLTEKVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQEIQDarkqELRELVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQTELDRLL 370
                 588899999999999888888888888888888888888888888888775333444555588899999999999999999999999999999998875 PP

        Spc7 234 e 234
                  
  EEA20797.1 371 P 371
                 5 PP

>> FlaC_arch  Flagella accessory protein C (FlaC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.1     0.062        59      17      35 ..     109     127 ..      98     131 .. 0.80
   2 ?    4.3   2.1     0.057        54       2      36 ..     133     167 ..     130     173 .. 0.87
   3 ?    5.2   0.9      0.03        28       7      31 ..     177     201 ..     170     206 .. 0.77
   4 ?    0.3   0.1         1   9.5e+02       1      22 [.     206     227 ..     206     242 .. 0.82
   5 ?    9.0   0.6    0.0019       1.8       1      39 [.     280     318 ..     280     321 .. 0.93
   6 ?    3.3   2.0      0.12   1.1e+02       4      37 ..     326     359 ..     323     370 .. 0.76

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.062
   FlaC_arch  17 etvkkeneelsksveelke 35 
                 +++++e  el+ks+e+++ 
  EEA20797.1 109 DSLRAEVTELRKSLEQIQH 127
                 6899999999999999975 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.057
   FlaC_arch   2 idelEnklsklsteletvkkeneelsksveelken 36 
                 ++ l++kl++ + + + +++++++l + v+++k +
  EEA20797.1 133 MEALQQKLNESEDKKTQAETQFQKLLERVNTIKSQ 167
                 67899999999999999999999999999999876 PP

  == domain 3  score: 5.2 bits;  conditional E-value: 0.03
   FlaC_arch   7 nklsklsteletvkkeneelsksve 31 
                 ++ls+  +++e ++++n+ l+ +v 
  EEA20797.1 177 EELSQARSRIEELEDQNSALKAEVS 201
                 6788888888888888888888875 PP

  == domain 4  score: 0.3 bits;  conditional E-value: 1
   FlaC_arch   1 ridelEnklsklsteletvkke 22 
                 +i  lE++  ++s el+++++ 
  EEA20797.1 206 KIAGLEKDAREHSNELSNLRNR 227
                 6778999999999999999975 PP

  == domain 5  score: 9.0 bits;  conditional E-value: 0.0019
   FlaC_arch   1 ridelEnklsklsteletvkkeneelsksveelkenVkd 39 
                 ++++lE++ls+l  e +++ ++n+  s++++ l++  ++
  EEA20797.1 280 KVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQE 318
                 89******************************9988765 PP

  == domain 6  score: 3.3 bits;  conditional E-value: 0.12
   FlaC_arch   4 elEnklsklsteletvkkeneelsksveelkenV 37 
                 el + +++ + +le +++++++++k  ee + + 
  EEA20797.1 326 ELRELVQSSDAQLEELREKLQQVEKRAEEANTDL 359
                 6667778888888888888888888888766655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (537 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      4217  (0.235206); expected 358.6 (0.02)
Passed bias filter:                      911  (0.0508115); expected 358.6 (0.02)
Passed Vit filter:                       333  (0.0185733); expected 17.9 (0.001)
Passed Fwd filter:                       186  (0.0103743); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              19  [number of targets reported over threshold]
# CPU time: 2.78u 0.36s 00:00:03.13 Elapsed: 00:00:00.71
# Mc/sec: 2293.62
//
Query:       EEA20798.1  [L=405]
Description: Golgi matrix protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.3e-09   35.9   0.1    1.2e-08   34.5   0.1    1.9  1  GRAB            GRIP-related Arf-binding domain
     0.0021   18.1  59.3       0.16   12.1  13.8    3.8  3  TPR_MLP1_2      TPR/MLP1/MLP2-like protein
     0.0062   14.1  44.9     0.0074   13.9  44.9    1.1  1  DUF3584         Protein of unknown function (DUF3584)
  ------ inclusion threshold ------
      0.027   14.7  45.4       0.28   11.4  10.7    4.2  3  Seryl_tRNA_N    Seryl-tRNA synthetase N-terminal domain
      0.028   14.3  46.5       0.29   11.0  44.8    2.4  1  Apolipoprotein  Apolipoprotein A1/A4/E domain
      0.031   13.2  51.7        0.1   11.4  17.7    2.3  2  Spc7            Spc7 kinetochore protein
      0.037   14.3  18.5       0.55   10.5   0.4    4.3  4  DUF948          Bacterial protein of unknown function (DUF948
       0.12   11.8  51.2       0.35   10.3  14.3    3.1  3  Golgin_A5       Golgin subfamily A member 5
       0.15   10.0  24.9      0.061   11.3   8.1    2.2  2  Prominin        Prominin
        0.2   11.1  52.7      0.089   12.2  19.3    2.2  2  HMMR_N          Hyaluronan mediated motility receptor N-termi
       0.21   11.4  47.7       0.67    9.7  16.6    2.3  2  FAM184          Family with sequence similarity 184, A and B
       0.39   10.0  37.8       0.85    8.9  21.8    2.5  2  DUF4407         Domain of unknown function (DUF4407)
        0.4   10.9  30.1        1.7    8.8  11.2    3.3  3  Fib_alpha       Fibrinogen alpha/beta chain family
       0.42    9.6  44.2        1.1    8.2  14.3    2.2  2  Atg14           Vacuolar sorting 38 and autophagy-related sub
       0.64   10.0  31.9        1.8    8.6   5.0    3.6  3  Laminin_II      Laminin Domain II
       0.92    9.5   5.2       0.53   10.3   0.4    3.2  2  TTRAP           Putative tranposon-transfer assisting protein
          1   10.0  43.9      0.082   13.5  10.6    4.3  5  BST2            Bone marrow stromal antigen 2
        1.5    9.0  57.5        6.4    6.9  25.1    4.0  2  ATG16           Autophagy protein 16 (ATG16)
        1.5    8.3  44.5        1.9    8.0  17.3    2.4  2  Filament        Intermediate filament protein
        1.6    8.4   5.2         13    5.5   0.0    3.4  3  Vac_Fusion      Chordopoxvirus multifunctional envelope prote
        1.7    8.6  11.4        1.3    9.0   2.5    3.9  3  Pox_A_type_inc  Viral A-type inclusion protein repeat
        1.9    7.4  41.7       0.25   10.3  11.4    3.1  3  IFT57           Intra-flagellar transport protein 57
          4    8.0  18.3        6.7    7.3   4.6    4.1  2  YtxH            YtxH-like protein
        4.2    6.6  29.6        3.3    6.9  16.5    2.8  2  CorA            CorA-like Mg2+ transporter protein
        4.4    7.2  32.8       0.66    9.9   6.6    4.2  4  LMP             LMP repeated region
        4.4    6.3  30.0      0.014   14.5   3.8    3.2  3  FH2             Formin Homology 2 Domain
        5.8    5.0  39.7         62    1.6  39.7    2.1  1  EzrA            Septation ring formation regulator, EzrA
        5.9    7.2  33.6       0.38   11.0   3.9    4.9  5  XhlA            Haemolysin XhlA
        8.7    6.8  31.1        1.2    9.6   0.6    5.7  5  FlaC_arch       Flagella accessory protein C (FlaC)
        8.8    7.0   9.2        3.5    8.3   1.1    3.7  3  VWA_2           von Willebrand factor type A domain
          9    6.7  47.9        2.8    8.4  12.7    3.2  3  Fez1            Fez1


Domain annotation for each model (and alignments):
>> GRAB  GRIP-related Arf-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.5   0.1   2.1e-11   1.2e-08       1      19 []     276     294 ..     276     294 .. 0.97

  Alignments for each domain:
  == domain 1  score: 34.5 bits;  conditional E-value: 2.1e-11
        GRAB   1 sseenVDKrLISNLllsFL 19 
                 ++e+nVD+++++N+ll+FL
  EEA20798.1 276 KPEDNVDRHVVTNHLLHFL 294
                 79****************9 PP

>> TPR_MLP1_2  TPR/MLP1/MLP2-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.1  13.8   0.00027      0.16      60     122 ..       2      64 ..       1      68 [. 0.96
   2 !    9.4  10.2    0.0018         1      53     113 ..      69     129 ..      65     134 .. 0.90
   3 !    7.6  19.5    0.0064       3.7      29     116 ..     147     235 ..     138     268 .. 0.50

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00027
  TPR_MLP1_2  60 qalreelnelkaeiaelkaeaesakaeleeseesweeqkeelekelselekriedlneqNklL 122
                 +al ++lne +++ ++++++ +++ + +++ ++++ e+ +e  +els++++rie+l++qN+ L
  EEA20798.1   2 EALQQKLNESEDKKTQAETQFQKLLERVNTIKSQLGERLKEDAEELSQARSRIEELEDQNSAL 64 
                 68999*******************************************************998 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.0018
  TPR_MLP1_2  53 aedvkelqalreelnelkaeiaelkaeaesakaeleeseesweeqkeelekelselekrie 113
                 +e++++++ l +++ e  +e+++l+++a+  ++++++++e++ eq++ ++ e +e+++ + 
  EEA20798.1  69 SENLTKIAGLEKDAREHSNELSNLRNRANLSQQNWQQEKEELIEQESYIRAEFEEAKQAMH 129
                 78889999999999999***********************************999999765 PP

  == domain 3  score: 7.6 bits;  conditional E-value: 0.0064
  TPR_MLP1_2  29 edlekqaeiakeaqqkYerelvkhaedvkelqalreelnelkaei.aelkaeaesakaeleeseesweeqkeelekelselekriedln 116
                 e+++  +e+++   + Y + +  ++++++++  l   l+e+++ + +el++ ++s  a+lee +e++++ +++ e+  ++l++  ++l+
  EEA20798.1 147 EKVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQEIQDARkQELRELVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQTELD 235
                 33333334444444444444444444444444444444444332213344444444444444444444444444444444444433333 PP

>> DUF3584  Protein of unknown function (DUF3584)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9  44.9   1.3e-05    0.0074     276     507 ..       2     236 ..       1     268 [. 0.83

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.3e-05
     DUF3584 276 erlaekqeevqeakaelkqqlrtledelkeaidelnqelsaakaklaakeselealeeqkkkyeda...dieklkadldqlpsirseleeleeeldalt 371
                 e+l++k++e + +k + ++q+++l + +++ +++l ++l++  ++l++++s++e+le+q+ + + +   ++ k +     + + ++el++l ++ ++  
  EEA20798.1   2 EALQQKLNESEDKKTQAETQFQKLLERVNTIKSQLGERLKEDAEELSQARSRIEELEDQNSALKAEvseNLTKIAGLEKDAREHSNELSNLRNRANLSQ 100
                 57889999****************************************************99987611155555555667889999************* PP

     DUF3584 372 ekhqdvqekydrrkqkikeeleeeleklkerleaireekdrl..kaaieealealesqlrkqleaqkeelneeekelesrlselklrldsatateEele 468
                 ++ q+ +e++ ++++ i  e+ee+ + +++ +    ee+  +  +++  ++le++ s+lr++ + + ++ n  + +    l+++ + +++a  ++E+ e
  EEA20798.1 101 QNWQQEKEELIEQESYIRAEFEEAKQAMHNWEVLAMEERSIRegLTEKVNDLEEQLSSLRDEYNSAVSDNNT-QSNTIDGLQRALQEIQDAR-KQELRE 197
                 **********************99999999855555555443247777777777777777776666666444.4555567777777666664.679999 PP

     DUF3584 469 qieeadealekaqeelekaeaevealqaeeeqlrkkrde 507
                   + +d++le+ +e+l++ e++ e+++++++q++++ d 
  EEA20798.1 198 LVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQTELDR 236
                 9999******************************99886 PP

>> Seryl_tRNA_N  Seryl-tRNA synthetase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4  10.7   0.00049      0.28      28      92 ..       5      70 ..       1      75 [. 0.91
   2 ?    6.2   7.0      0.02        12      24      85 ..      68     130 ..      65     137 .. 0.89
   3 ?    8.8  12.6    0.0031       1.8      19      99 ..     137     222 ..     133     239 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00049
                  HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTT.S-TCCCCCCCHHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N 28 vdelleldekrrelqveleelqaerNelskeIgkakkkk.edaeeliaevkelkeelkaleaelke 92
                   ++l e ++k+ ++++++++l ++ N++  + g+  k++ e+ ++ + +++el ++ +al+ae++e
    EEA20798.1  5 QQKLNESEDKKTQAETQFQKLLERVNTIKSQLGERLKEDaEELSQARSRIEELEDQNSALKAEVSE 70
                  5789999*****************************9999999******************99987 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.02
                   CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTT.S-TCCCCCCCHHHHHHHHH CS
  Seryl_tRNA_N  24 dkadvdelleldekrrelqveleelqaerNelskeIgkakkkk.edaeeliaevkelkeelka 85 
                    ++++ ++  l++  re+ +el +l+++ N  +++ ++ k++  e+ + ++ae +e k+ + +
    EEA20798.1  68 VSENLTKIAGLEKDAREHSNELSNLRNRANLSQQNWQQEKEELiEQESYIRAEFEEAKQAMHN 130
                   678999*******************************99999999999999999999998766 PP

  == domain 3  score: 8.8 bits;  conditional E-value: 0.0031
                   CCCTCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTT.....S-TCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH CS
  Seryl_tRNA_N  19 kkRgedkadvdelleldekrrelqveleelqaerNelskeIgkakkkk.....edaeeliaevkelkeelkaleaelkeleaelek 99 
                   ++R   + + +++ +l+e+  +l+ e +++ +  N+ s++I  + ++      + ++el++ v++  ++l++l ++l+++e++ e+
    EEA20798.1 137 EERSIREGLTEKVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALqeiqdARKQELRELVQSSDAQLEELREKLQQVEKRAEE 222
                   66777888999*******************************99998855555556666666666666667777777666666655 PP

>> Apolipoprotein  Apolipoprotein A1/A4/E domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0  44.8   0.00051      0.29       3     186 ..      12     225 ..      10     249 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00051
                     HHCCCCHHHHHCCHHHCHHCHHHHHHHHHHHHHHHHHHHH..HHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCHHCCHH CS
  Apolipoprotein   3 eesldelkayaeeleeqlaplaqelrdrlskeleelrarl..raeleevrarlepyrdevqeqlgqnleelrqrlapyteelrerlaadaeelqe 95 
                     e++  ++++++++l e+++ +  +l +rl +++eel+++    +ele+++++l++ ++e  ++++   ++ r++ ++ +++lr+r+++  ++ q+
      EEA20798.1  12 EDKKTQAETQFQKLLERVNTIKSQLGERLKEDAEELSQARsrIEELEDQNSALKAEVSENLTKIAGLEKDAREH-SNELSNLRNRANLSQQNWQQ 105
                     6788899**************99********9999977543338888888888888888888888877777777.77788888888888888888 PP

                     CHCCHCHH...........................HHHHHHHHHHHHHHHHCHHHHHHHH..HHHHHHHHHHH-----..-----SSSHHHHHHH CS
  Apolipoprotein  96 qlavyaee...........................lrerlerhvealkarlapyveelrq..klaerleelkeslaphaeeveerlssrveelre 161
                       ++  e+                           +re+l ++v +l ++l+ +++e  +  +      +  + l+ +++e++++  ++++el +
      EEA20798.1 106 EKEELIEQesyiraefeeakqamhnwevlameersIREGLTEKVNDLEEQLSSLRDEYNSavSDNNTQSNTIDGLQRALQEIQDARKQELRELVQ 200
                     88888888***************************************************733333344456677777777778888888888888 PP

                     TS-TTSHHHHHS--XXXXXXXXXXX CS
  Apolipoprotein 162 kleeqaeelrerleanleelkaqle 186
                     + ++q+eelre+l+++ ++ ++  +
      EEA20798.1 201 SSDAQLEELREKLQQVEKRAEEANT 225
                     8888888888888887777776544 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1  25.9    0.0018       1.1     156     293 ..       2     140 ..       1     142 [. 0.85
   2 ?   11.4  17.7   0.00018       0.1     140     233 ..     141     238 ..     139     251 .. 0.73

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0018
        Spc7 156 elLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeae 254
                 e L+++ +e ++ + + e+++++l e++++++++  e  + d eeL ++r++++el+ + +++k+e++e  ++++ le++  e +++ s+l+++ + ++
  EEA20798.1   2 EALQQKLNESEDKKTQAETQFQKLLERVNTIKSQLGERLKEDAEELSQARSRIEELEDQNSALKAEVSENLTKIAGLEKDAREHSNELSNLRNRANLSQ 100
                 56888888888889999999999999999999988888889***************************************************9999888 PP

        Spc7 255 rvleeckgwsesevsrlkeevkal.eeltgwkivslsgst 293
                 +  +++k+   ++ s +++e+++  +  ++w+++ +++ +
  EEA20798.1 101 QNWQQEKEELIEQESYIRAEFEEAkQAMHNWEVLAMEERS 140
                 8777777777666677888887651567999999888765 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00018
        Spc7 140 LkegleenlegleedkelLekqeeeldellpeleeekaeleeeleklqe....aaeelesidkeeLeelreelaelkaeieekkkelaelqeqleele 233
                 ++egl+e++++lee+ + L ++ + + +  +  ++  + l++ l+++q+    + +el ++  ++Leelre+l+++++  ee +++l++ q++l++l 
  EEA20798.1 141 IREGLTEKVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQEIQDarkqELRELVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQTELDRLL 238
                 77888888888888888888888888777777777777777777777765333444555577889999999999999999999999999999988875 PP

>> DUF948  Bacterial protein of unknown function (DUF948)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.4       1.1   6.5e+02      30      65 ..       3      38 ..       1      46 [. 0.62
   2 ?    8.0   2.0    0.0059       3.4      25      73 ..      44      92 ..      17     105 .. 0.88
   3 ?   10.5   0.4   0.00094      0.55      29      82 ..     143     189 ..     124     193 .. 0.74
   4 ?    5.2   2.2     0.043        25      34      64 ..     183     231 ..     175     256 .. 0.45

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 1.1
      DUF948 30 eaaatieelekqvdpilkevedllakvnelledvne 65
                ++++ ++e e++ ++  ++ ++ll+ vn++ +++ e
  EEA20798.1  3 ALQQKLNESEDKKTQAETQFQKLLERVNTIKSQLGE 38
                556666666666666666777777777776555544 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0059
      DUF948 25 kktldeaaatieelekqvdpilkevedllakvnelledvneklekvdpl 73
                ++ l++a+++ieele+q  ++  ev + l+k+  l +d +e+++++ +l
  EEA20798.1 44 AEELSQARSRIEELEDQNSALKAEVSENLTKIAGLEKDAREHSNELSNL 92
                5678999*******************************99999988776 PP

  == domain 3  score: 10.5 bits;  conditional E-value: 0.00094
      DUF948  29 deaaatieelekqvdpilkevedllakvnelledvneklekvdplteavadlge 82 
                 + +++ +++le+q+ ++ +e + +++  n+       +++++d l  a++++ +
  EEA20798.1 143 EGLTEKVNDLEEQLSSLRDEYNSAVSDNNT-------QSNTIDGLQRALQEIQD 189
                 445666666666666666666666666666.......99999999999999876 PP

  == domain 4  score: 5.2 bits;  conditional E-value: 0.043
      DUF948  34 tieele..................kqvdpilkevedllakvnelledvn 64 
                 +++e++                  +++++ l++ve+  +++n+ l++ +
  EEA20798.1 183 ALQEIQdarkqelrelvqssdaqlEELREKLQQVEKRAEEANTDLKQAQ 231
                 4444443333111111122222222333333333333333333333344 PP

>> Golgin_A5  Golgin subfamily A member 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7  16.1     0.031        18      45     136 ..       4      95 ..       1     102 [. 0.85
   2 ?   10.3  14.3   0.00061      0.35      36     135 ..      69     168 ..      62     177 .. 0.86
   3 ?    8.0  13.1     0.003       1.7      70     144 ..     180     257 ..     164     279 .. 0.48

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.031
   Golgin_A5  45 lsaeldelkqerdllreelqklnqqieqlrtelqdleaqqqaeaeslreqlqeleeqleeerkakeeveaelerlkeelryleeelvrskat 136
                 l+++l+e ++++ +++ + qkl +++++++++l +  ++  +e +++r +++ele+q ++ +++  e  ++++ l+++ r   +el++ ++ 
  EEA20798.1   4 LQQKLNESEDKKTQAETQFQKLLERVNTIKSQLGERLKEDAEELSQARSRIEELEDQNSALKAEVSENLTKIAGLEKDAREHSNELSNLRNR 95 
                 67889999999999999999999999999999988888888999999999999999999999999999999999999999999999876655 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00061
   Golgin_A5  36 eeglesstalsaeldelkqerdllreelqklnqqieqlrtelqdleaqqqaeaeslreqlqeleeqleeerkakeeveaelerlkeelryleeelvrsk 134
                 +e+l     l+++  e ++e   lr+  + ++q+ +q + el + e+   ae+e++++ +++ e    eer+ +e + ++++ l+e+l++l++e   + 
  EEA20798.1  69 SENLTKIAGLEKDAREHSNELSNLRNRANLSQQNWQQEKEELIEQESYIRAEFEEAKQAMHNWEVLAMEERSIREGLTEKVNDLEEQLSSLRDEYNSAV 167
                 445555566778888889999999**********************************************************************87655 PP

   Golgin_A5 135 a 135
                 +
  EEA20798.1 168 S 168
                 5 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.003
   Golgin_A5  70 ieqlrtelqdleaqqqae.aeslreqlqeleeqleeerkakeeveaelerlkeelryle..eelvrskatlqsrikdr 144
                 +++  +e+qd  +q+  e ++s+  ql+el+e+l++ +k+ ee++++l++ + el++l   e  v++k+ l +++++ 
  EEA20798.1 180 LQRALQEIQDARKQELRElVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQTELDRLLpfEKEVKEKNLLIGKLRHE 257
                 223333333333333333223334455555555555555555555555555555555432233344444444444444 PP

>> Prominin  Prominin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0  10.5     0.033        19     632     714 ..       3      88 ..       1     116 [. 0.76
   2 ?   11.3   8.1   0.00011     0.061     277     378 ..     139     237 ..     101     249 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.033
    Prominin 632 kleelanelsngkknlkqslkneaqdlraiqqelvlplessvkklkksvkklde...ensdlqesikkllaaveraenflkkngse 714
                  l+++ ne + +k+++++++++  + +++i+++l ++l++ +++l +   +++e   +ns l++++++ l+++  +e+  +++ +e
  EEA20798.1   3 ALQQKLNESEDKKTQAETQFQKLLERVNTIKSQLGERLKEDAEELSQARSRIEEledQNSALKAEVSENLTKIAGLEKDAREHSNE 88 
                 4455555555555899999*******************99999998876666666669999*****99999999888866665554 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00011
    Prominin 277 rgvkrdlnqalsnlCqseeCskilssleiekldtskcldqlpnvdevlealeevletnlssivkeglarlneipekvknqtaevvpdlkkalakgreqi 375
                 r++++ l++ +++l  +e+ s+++++++    d++++ ++++ +++ l++++++ +++l ++v+++ a+l+e++ek++ q+++  ++   +l+++++++
  EEA20798.1 139 RSIREGLTEKVNDL--EEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQEIQDARKQELRELVQSSDAQLEELREKLQ-QVEKRAEEANTDLKQAQTEL 234
                 55666666666662..35788899999999999*******************************************96.78888999999999999988 PP

    Prominin 376 kkl 378
                 ++l
  EEA20798.1 235 DRL 237
                 765 PP

>> HMMR_N  Hyaluronan mediated motility receptor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7  26.8      0.06        35     207     321 ..       3     128 ..       1     133 [. 0.73
   2 ?   12.2  19.3   0.00015     0.089     202     309 ..     146     248 ..     125     268 .. 0.81

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.06
      HMMR_N 207 qLkeklvslekekieekseteklleyieels.nvseqlekykldiaqleellkekndeiesLkssLeekeqelskqvkdlnekcklle..........k 294
                 +L++kl ++e++k++  ++ +klle ++ ++ ++ e+l    +++ q+++ ++e +d+ + Lk +++e+ +++    kd+ e+ ++l           +
  EEA20798.1   3 ALQQKLNESEDKKTQAETQFQKLLERVNTIKsQLGERLKEDAEELSQARSRIEELEDQNSALKAEVSENLTKIAGLEKDAREHSNELSnlrnranlsqQ 101
                 799**********999999******99999625788998889999999999***************999988766666666666666644455555432 PP

      HMMR_N 295 ekeelvreeeekeqtlsaEleelkekl 321
                 + +++ +e  e+e+ + aE ee k+++
  EEA20798.1 102 NWQQEKEELIEQESYIRAEFEEAKQAM 128
                 222222333455566666666666655 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 0.00015
      HMMR_N 202 kakvaqLkeklvslekekieekseteklleyieelsnvseqlekykldiaqleellkekndeiesLkssLeekeqelskqvkdlnekckllekekeelv 300
                  +kv  L+e+l+sl +e +   s+++ + + i+ l+ + +++     + ++l+el+++ + ++e+L+++L++ e+    +++++n+ +k+ ++e++ l+
  EEA20798.1 146 TEKVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQEI--QDARKQELRELVQSSDAQLEELREKLQQVEK----RAEEANTDLKQAQTELDRLL 238
                 689**************************************9..5666789**************9999998766....88888888888888888776 PP

      HMMR_N 301 r.eeeekeqt 309
                   e+e+ke++
  EEA20798.1 239 PfEKEVKEKN 248
                 4244444444 PP

>> FAM184  Family with sequence similarity 184, A and B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3  24.7     0.013       7.4      56     185 ..       2     132 ..       1     138 [. 0.79
   2 ?    9.7  16.6    0.0012      0.67      86     184 ..     137     237 ..     132     257 .. 0.78

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.013
      FAM184  56 aeleesleqhekekrqalaefeqykrrveerelkleaehsqkvvelsreveevkrkFeeklrqfaqlqeqleqekeka......LeelrkkhreeveeL 148
                 ++l+++l++ e +k qa ++f    ++  er +  +++  +++ e ++e+ +++   ee   q + l++++ +    +      Le+  ++h++e+++L
  EEA20798.1   2 EALQQKLNESEDKKTQAETQF----QKLLERVNTIKSQLGERLKEDAEELSQARSRIEELEDQNSALKAEVSE----NltkiagLEKDAREHSNELSNL 92 
                 578899999999999998888....455566677788888888888888888887666655555555555553....333334599999********** PP

      FAM184 149 lkeqeaqsekllkeqekl...eekhkaeveklkeeveele 185
                 +++ +  ++++++e+e+l   e+ ++ae e++k++++++e
  EEA20798.1  93 RNRANLSQQNWQQEKEELieqESYIRAEFEEAKQAMHNWE 132
                 ******************9877789**********99987 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.0012
      FAM184  86 relkleaehsqkvvelsreveevkrkFeeklrqfaqlqeqleqekekaLeelrkkhreeveeLlkeqeaqsekllkeqekl...eekhkaeveklkeev 181
                 +e + ++  ++kv  l++++  ++ +++ ++++ +  q++     ++aL+e++ + ++e+ eL+++++aq e+l +  +++   +e+ ++++++++ e+
  EEA20798.1 137 EERSIREGLTEKVNDLEEQLSSLRDEYNSAVSDNNT-QSNTIDGLQRALQEIQDARKQELRELVQSSDAQLEELREKLQQVekrAEEANTDLKQAQTEL 234
                 5667788889*********************99655.5556667899*************************999988888333445555566655555 PP

      FAM184 182 eel 184
                 ++l
  EEA20798.1 235 DRL 237
                 555 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9  21.8    0.0015      0.85     108     243 ..      32     180 ..       1     181 [. 0.66
   2 ?    7.4  19.6    0.0041       2.4     136     243 ..     136     237 ..      99     246 .. 0.70

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0015
     DUF4407 108 Idaelaeeqqeeakelkeqlaaa..........ltaelaeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaake....kkaql 192
                 I+++l e                          ++++++ele+q++al+ae+++  ++++ l+++a+++ + + ++  ++ +   ++ ++      +q 
  EEA20798.1  32 IKSQLGE---------------RlkedaeelsqARSRIEELEDQNSALKAEVSENLTKIAGLEKDAREHSN-ELSNLRNRANLSQQNWQQekeeLIEQE 114
                 3333333...............1333344444588899999999999999999999999999999886655.444443333334444444211222222 PP

     DUF4407 193 daaqaelaelkakld...................atarlaalraelaeleaerakeraasqaaaaaddGl 243
                   ++ae +e+    +                    t+++++l+++l++l++e+++++++++++++  dGl
  EEA20798.1 115 SYIRAEFEEA----KqamhnwevlameersiregLTEKVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGL 180
                 2233344444....1344588888889999***********************************99997 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0041
     DUF4407 136 aeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaakekkaqldaaqaelaelkakldatarlaalraelaeleaerakeraasq 234
                  e+++ ++ l ++++ +e++l+ lr+e+++ ++ + +t+ + + G     ++ ++  da+++el el ++  ++a+l++lr++l+++e+++++++++ +
  EEA20798.1 136 MEERSIREGLTEKVNDLEEQLSSLRDEYNSAVSDN-NTQSNTIDGL---QRALQEIQDARKQELRELVQS--SDAQLEELREKLQQVEKRAEEANTDLK 228
                 34455556999999999999999999999999964.4444445554...666777888888999999999..999999999999999999999999888 PP

     DUF4407 235 aaaaaddGl 243
                 +a+ + d l
  EEA20798.1 229 QAQTELDRL 237
                 888776655 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8  11.2    0.0029       1.7      33     130 ..       4     101 ..       1     107 [. 0.88
   2 ?    4.9   9.3     0.049        28      23      96 ..     142     216 ..     137     237 .. 0.65
   3 ?    6.4   6.5     0.017       9.6      37     110 ..     177     257 ..     169     268 .. 0.64

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0029
                 CCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  33 vkkdlekleneleeisnstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvLqnvlesneqkiqkLeqdidqker 130
                 ++++l++ e++ ++++ + ++  e v++ik++l e+ k+++++ +  ++  +ele++ + lk++++++ ++i  L +  ++ ++++++L++  +  ++
  EEA20798.1   4 LQQKLNESEDKKTQAETQFQKLLERVNTIKSQLGERLKEDAEELSQARSRIEELEDQNSALKAEVSENLTKIAGLEKDAREHSNELSNLRNRANLSQQ 101
                 5677888888888888889999999****************998888888999************************************998776655 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.049
                 HHCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHHCCCHHHHH CS
   Fib_alpha  23 qdlllkyekdvkkdlekleneleeisnstkeaeelvkeikdslrekqkskkdn.dnvikksskeleeeilrlket 96 
                 ++ l+++ +d++++l++l++e +++ + +++ ++++  ++  l+e q   k++  +++++s  +lee  ++l++ 
  EEA20798.1 142 REGLTEKVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQEIQDARKQElRELVQSSDAQLEELREKLQQV 216
                 555667777778888888888888888888888888888888888777777666777777777777444444332 PP

  == domain 3  score: 6.4 bits;  conditional E-value: 0.017
                 HCCCCCCCCCCC........CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHH CS
   Fib_alpha  37 lekleneleeis........nstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvLqnv 110
                 ++ l++ l+ei+        +  ++++   +e++++l++ +k +++ ++ +k+ ++el+ + l ++++++++   i +L+  
  EEA20798.1 177 IDGLQRALQEIQdarkqelrELVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQTELD-RLLPFEKEVKEKNLLIGKLRHE 257
                 55555555555410000000444556666667777777777777777889999999999.9999999999998888888865 PP

>> Atg14  Vacuolar sorting 38 and autophagy-related subunit 14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1  22.6    0.0044       2.6      26     137 ..       3     115 ..       1     140 [. 0.82
   2 ?    8.2  14.3     0.002       1.1      35     131 ..     139     233 ..     129     259 .. 0.87

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0044
       Atg14  26 elrerlaklksekeslkkkiekalegke.eaeqledkiknkkakleelksliadlrerlqelkdklsqlkkeieekkkklaklsdklkkRrsdleslqn 123
                  l+++l     +k + +++++k+le+ +  ++ql +++k +++ l++ +s+i++l+++++ lk+ +s++  +i+   k  +++s++l+  r ++++ q+
  EEA20798.1   3 ALQQKLNESEDKKTQAETQFQKLLERVNtIKSQLGERLKEDAEELSQARSRIEELEDQNSALKAEVSENLTKIAGLEKDAREHSNELSNLRNRANLSQQ 101
                 567777777777888888888888887777799999*********************************************************9***** PP

       Atg14 124 eleerrkkqiaklq 137
                   +++++++i++ +
  EEA20798.1 102 NWQQEKEELIEQES 115
                 99999999998754 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.002
       Atg14  35 ksekeslkkkiekalegkeeaeqledkiknkkakleelksliadlrerlqelkdklsq.lkkeieekkkklaklsdklkkRrsdleslqneleerrkk 131
                 +s +e l +k+++++e+ +   +l+d+  +   + +++ ++i  l++ lqe++d ++q l++ ++   ++l++l++kl +  +++e +++ l++++++
  EEA20798.1 139 RSIREGLTEKVNDLEEQLS---SLRDEYNSAVSDNNTQSNTIDGLQRALQEIQDARKQeLRELVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQTE 233
                 577899999***9999999...99999999999999*****************99876267777888899*********8888888999999999875 PP

>> Laminin_II  Laminin Domain II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   9.2      0.04        23      21     107 ..       3      87 ..       1      90 [. 0.74
   2 ?    6.4   4.1     0.015       8.5      23      91 ..     104     170 ..      91     193 .. 0.64
   3 ?    8.6   5.0    0.0031       1.8      12      55 ..     192     235 ..     174     256 .. 0.67

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.04
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--TTTTTGGGHHHHHHHHHH....HHHHHHHHHHHHHHHHHHHH CS
  Laminin_II  21 plsqnlentkeklseinrsveetnekvkdankairdArrsvkkLeklapqLldklkelkqleeasss.lsdniseikelIaqARkaAn 107
                 +l+q+l++ ++k  +++++    +++++  n++  + ++  k+  +++ q  ++++el+ +++a ++ +s+n+ +i  l + AR+  n
  EEA20798.1   3 ALQQKLNESEDKKTQAETQ---FQKLLERVNTIKSQLGERLKEDAEELSQARSRIEELEDQNSALKAeVSENLTKIAGLEKDAREHSN 87 
                 6777777777777777777...555666666666667777777777777778888888888888888999999999999999999877 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.015
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.X--TTTTTGGGHHHHHHHHHH...HHHH CS
  Laminin_II  23 sqnlentkeklseinrsveetnekvkdankairdArrsvkk.LeklapqLldklkelkqleeassslsdn 91 
                 +q+ e++ e+ s i+++ ee ++ +++   +++  +rs+++ L++++++L+++l++l+   +   ++sdn
  EEA20798.1 104 QQEKEELIEQESYIRAEFEEAKQAMHNWE-VLAMEERSIREgLTEKVNDLEEQLSSLRDEYNS--AVSDN 170
                 45555555666667777777776666654.444555565544***********9999875544..35554 PP

  == domain 3  score: 8.6 bits;  conditional E-value: 0.0031
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Laminin_II  12 akevleqlaplsqnlentkeklseinrsveetnekvkdankair 55 
                  +e  e ++  +++le+++ekl+++++ +ee n ++k+a++ ++
  EEA20798.1 192 KQELRELVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQTELD 235
                 34555666666777777777777777777777777777666554 PP

>> TTRAP  Putative tranposon-transfer assisting protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.1       6.9     4e+03      19      35 ..      24      45 ..      20      60 .. 0.64
   2 ?   10.3   0.4   0.00092      0.53      14      52 ..     170     211 ..     160     213 .. 0.87

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 6.9
                HHHHHHHHSTTTS......-HH CS
       TTRAP 19 elieelkaalkyl.....edde 35
                +l+e+ +++ ++l     ed+e
  EEA20798.1 24 KLLERVNTIKSQLgerlkEDAE 45
                5677777777777555544443 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00092
                 -SHHHHHHHHHHHSTTTS....-HHHHHHHHHHHHHHTT--H CS
       TTRAP  14 egtRkelieelkaalkyl...eddelreLaestlaKLkaltD 52 
                 ++t +++i+ l+ al+ +   + +elreL++s  a L++l++
  EEA20798.1 170 NNTQSNTIDGLQRALQEIqdaRKQELRELVQSSDAQLEELRE 211
                 56999*************887789*******99999998887 PP

>> BST2  Bone marrow stromal antigen 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2  10.5    0.0015       0.9      21      88 ..       3      74 ..       1      77 [. 0.81
   2 ?   -0.5   1.2       3.3   1.9e+03      22      36 ..      99     113 ..      79     133 .. 0.49
   3 ?   -1.4   1.3       6.4   3.7e+03      12      38 ..     107     133 ..      98     152 .. 0.64
   4 ?   13.5  10.6   0.00014     0.082      17      90 ..     147     221 ..     139     222 .. 0.90
   5 ?    1.8   1.0      0.63   3.7e+02      44      87 ..     228     270 ..     217     274 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.0015
                HHHHHHHHHHHHHHHHHHHHHH....HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        BST2 21 lLerqLtqaqeslreaeaqaat....cnqtvvtLkasLekekaqsqkqqakvqelqgeikkLnqkLqdaeae 88
                 L+++L++++++  +ae+q +      n +  +L + L+++  +  +++++++el++++  L+ ++ + +++
  EEA20798.1  3 ALQQKLNESEDKKTQAETQFQKllerVNTIKSQLGERLKEDAEELSQARSRIEELEDQNSALKAEVSENLTK 74
                59*****************9862222566666777778888888888899***************9998776 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 3.3
                 HHHHHHHHHHHHHHH CS
        BST2  22 LerqLtqaqeslrea 36 
                  +++ +q +e+l e+
  EEA20798.1  99 SQQNWQQEKEELIEQ 113
                 222222222222222 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 6.4
                 HHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        BST2  12 eqecrnvtrlLerqLtqaqeslreaea 38 
                 ++e+ +++ ++ ++  +a++ ++++e 
  EEA20798.1 107 KEELIEQESYIRAEFEEAKQAMHNWEV 133
                 345555555666666666666666665 PP

  == domain 4  score: 13.5 bits;  conditional E-value: 0.00014
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC CS
        BST2  17 nvtrlLerqLtqaqeslreaeaqaatcnqtvvtLkasLek.ekaqsqkqqakvqelqgeikkLnqkLqdaeaeve 90 
                 ++   Le+qL   +++ ++a  + +t ++t+  L+ +L++ + a++q+ ++ vq    ++++L +kLq+ e+  e
  EEA20798.1 147 EKVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQEiQDARKQELRELVQSSDAQLEELREKLQQVEKRAE 221
                 566779********************************98356899999*******************9988765 PP

  == domain 5  score: 1.8 bits;  conditional E-value: 0.63
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        BST2  44 nqtvvtLkasLekekaqsqkqqakvqelqgeikkLnqkLqdaea 87 
                 +q   +L   L  ek   ++++  + +l+ e  +Ln++L +a+ 
  EEA20798.1 228 KQAQTELDRLLPFEKEV-KEKNLLIGKLRHEAVTLNDHLTKALR 270
                 55556666666666666.45567899999999999999999875 PP

>> ATG16  Autophagy protein 16 (ATG16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   3.5       0.4   2.3e+02     160     188 ..       1      29 [.       1      40 [. 0.79
   2 ?    6.9  25.1     0.011       6.4      57     170 ..     151     268 ..     110     279 .. 0.69

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.4
       ATG16 160 lsaLqlqlnqaEeklrklekENkeLveRW 188
                 ++aLq +ln  E+k+ + e+  ++L+eR 
  EEA20798.1   1 MEALQQKLNESEDKKTQAETQFQKLLERV 29 
                 67899999999999999999999999985 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.011
       ATG16  57 sakekeasasqsnskqsakiqsleqklaqlreelaelyk.srgelaqrllelneelqkleeklkedeerlaeleaeraaletklkdr...eeelrekek 151
                 + +e+++s +++ ++  ++ +++++++  l+  l+e +  +++el + +++  ++l++l+ekl++ e+r +e++++ ++ +t+l+++   e+e++ek+ 
  EEA20798.1 151 DLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQEIQDaRKQELRELVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQTELDRLlpfEKEVKEKNL 249
                 333333444443333344444555666666677777665145677777888888999999999999999999999999999999987666999999999 PP

       ATG16 152 lvqdlqDElsaLqlqlnqa 170
                 l+ +l+ E ++L+ +l++a
  EEA20798.1 250 LIGKLRHEAVTLNDHLTKA 268
                 9999999999999888765 PP

>> Filament  Intermediate filament protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0  17.3    0.0034       1.9     182     281 ..      11     113 ..       2     116 .. 0.87
   2 ?    2.2  33.1       0.2   1.1e+02      23     232 ..      57     258 ..      56     273 .. 0.66

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0034
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Filament 182 aeknreeaeewykskleelqeaaeknsealrsakeeitelrrqiqsleieleslkkqkasleaqlaelee...rleaeleklqeklseleeelaeiree 277
                  e+++++ae ++++ le++++  ++ +e l++  ee++++r +i++le + ++lk++ +   +++a le+   ++++el++l++  +  +++ ++ +ee
  EEA20798.1  11 SEDKKTQAETQFQKLLERVNTIKSQLGERLKEDAEELSQARSRIEELEDQNSALKAEVSENLTKIAGLEKdarEHSNELSNLRNRANLSQQNWQQEKEE 109
                 678899**************************************************9999999999888622257888999999999999999999988 PP

                 HHHH CS
    Filament 278 marq 281
                 +  q
  EEA20798.1 110 LIEQ 113
                 7655 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.2
                 XXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
    Filament  23 LEqenkeLeakieeleekksaevsklkelyekeleelrkqldeltkerarlqleldnlreeledlrkkyekelnkreevEaelkalrkdldeatlarvd 121
                 LE +n++L+a+++e   k  a  +k+ +   +el++lr++    +  +++ q e ++l e+   +r+ +e+  +  ++ E           e+   r  
  EEA20798.1  57 LEDQNSALKAEVSENLTK-IAGLEKDAREHSNELSNLRNRA---NLSQQNWQQEKEELIEQESYIRAEFEEAKQAMHNWE-------VLAMEERSIREG 144
                 778888888888777777.6666666666666666666542...233334444555555555555555554333333333.......333455556777 PP

                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-H CS
    Filament 122 LekkvesLkeelaflkkvheeEvkelqkqvs.....eqvlvevdaarkldLteilkeiraqyeelaeknreeaeewykskleelqeaaeknsealrsak 215
                 L +kv+ L+e+l+ l+  ++  v++ ++q +     +++l e+++ark++L e ++   aq eel ek  +++e+  ++  ++l++ a+++ + l   +
  EEA20798.1 145 LTEKVNDLEEQLSSLRDEYNSAVSDNNTQSNtidglQRALQEIQDARKQELRELVQSSDAQLEELREK-LQQVEKRAEEANTDLKQ-AQTELDRLLPFE 241
                 88888888888888888888888877776655566677778999999999999999999999988665.56777777776666654.566677777888 PP

                 HHHHHHHHHHHHHHHHH CS
    Filament 216 eeitelrrqiqsleiel 232
                 +e++e +  i +l++e 
  EEA20798.1 242 KEVKEKNLLIGKLRHEA 258
                 88888888888888774 PP

>> Vac_Fusion  Chordopoxvirus multifunctional envelope protein A27
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.1       2.6   1.5e+03      12      30 ..      18      36 ..       7      60 .. 0.60
   2 ?    5.5   0.0     0.023        13       2      35 ..     149     182 ..     148     190 .. 0.89
   3 ?    3.3   0.2      0.11        63       2      33 ..     206     237 ..     205     239 .. 0.93

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 2.6
                HHHHHHHHHHHHHHHHHHH CS
  Vac_Fusion 12 lekdfqlvikcckrvneal 30
                 e++fq++ ++  + + +l
  EEA20798.1 18 AETQFQKLLERVNTIKSQL 36
                5566666666555554444 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.023
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH- CS
  Vac_Fusion   2 lkdleerllvlekdfqlvikcckrvnealkRlEn 35 
                 ++dlee+l +l ++++  ++   ++++ ++ l +
  EEA20798.1 149 VNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQR 182
                 689************************9998766 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.11
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Vac_Fusion   2 lkdleerllvlekdfqlvikcckrvnealkRl 33 
                 l++l e+l ++ek  ++     k+ +  l+Rl
  EEA20798.1 206 LEELREKLQQVEKRAEEANTDLKQAQTELDRL 237
                 689999***********************998 PP

>> Pox_A_type_inc  Viral A-type inclusion protein repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   2.5    0.0022       1.3       1      15 [.      45      59 ..      45      60 .. 0.91
   2 ?   -1.8   0.1       5.7   3.3e+03       2       9 ..      88      95 ..      87      95 .. 0.90
   3 ?    3.2   0.1      0.15        89       8      18 ..     147     157 ..     144     160 .. 0.90

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.0022
  Pox_A_type_inc  1 rEmsrlRsRIsDLEr 15
                    +E+s+ RsRI++LE 
      EEA20798.1 45 EELSQARSRIEELED 59
                    7*************6 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 5.7
  Pox_A_type_inc  2 EmsrlRsR 9 
                    E+s lR+R
      EEA20798.1 88 ELSNLRNR 95
                    9999**98 PP

  == domain 3  score: 3.2 bits;  conditional E-value: 0.15
  Pox_A_type_inc   8 sRIsDLErqLs 18 
                     +++ DLE qLs
      EEA20798.1 147 EKVNDLEEQLS 157
                     6999******8 PP

>> IFT57  Intra-flagellar transport protein 57
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3  11.4   0.00043      0.25     235     325 ..       3      93 ..       1      97 [. 0.93
   2 ?    3.3  11.1     0.058        33     210     299 ..      91     183 ..      83     190 .. 0.48
   3 ?    3.7   8.7     0.042        25     254     310 ..     180     237 ..     170     249 .. 0.73

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00043
       IFT57 235 sieeslpetksqlkklhedisktlekiesrEkylnsqleellqeyreaqeelsevkekykqlsegvseltrelaeiseelekvkqemeerg 325
                 +++++l+e++ + ++ +++++k le++++  ++l ++l+e  +e+++a+ +++e++++ + l+++vse  ++ a ++++ ++ ++e+ +  
  EEA20798.1   3 ALQQKLNESEDKKTQAETQFQKLLERVNTIKSQLGERLKEDAEELSQARSRIEELEDQNSALKAEVSENLTKIAGLEKDAREHSNELSNLR 93 
                 678999999999******************************************************************9999999987655 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.058
       IFT57 210 qLkvtikadakdWrahleqmkkhkksieeslpetksqlkk...lhedisktlekiesrEkylnsqleellqeyreaqeelsevkekykqlseg 299
                 +L+++ + +++ W+++ e++ + ++ i+++++e+k+++ +   l  +     e ++++ + l++ql++l +ey++a    +++++ ++ l++ 
  EEA20798.1  91 NLRNRANLSQQNWQQEKEELIEQESYIRAEFEEAKQAMHNwevLAMEERSIREGLTEKVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRA 183
                 455555555556666666666666666666666555554411133344444444444445555555555555555555554444444444444 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.042
       IFT57 254 isktlekie.srEkylnsqleellqeyreaqeelsevkekykqlsegvseltrelaei 310
                 ++++l++i+ +r + l + ++++ ++++e++e+l++v+++ +++++ +++ ++el+++
  EEA20798.1 180 LQRALQEIQdARKQELRELVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQTELDRL 237
                 5667777763577788888888888888888888888888888888888888888776 PP

>> YtxH  YtxH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   5.8      0.42   2.4e+02      30      72 ..      18      59 ..       2     129 .. 0.87
   2 ?    7.3   4.6     0.012       6.7      26      74 ..     141     213 ..     138     258 .. 0.90

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.42
        YtxH 30 lkekaddlkekakelleeakekakekaedlkekvkekadelke 72
                +  ++++l e+++ ++ ++ e+ ke ae+l+++ +++++el +
  EEA20798.1 18 AETQFQKLLERVNTIKSQLGERLKEDAEELSQA-RSRIEELED 59
                344588888999999888888889999999886.888888776 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.012
        YtxH  26 tRkdlkekaddlkekakelleeakeka........................kekaedlkekvkekadelkekv 74 
                  R+ l ek++dl e++ +l +e ++ +                        k++  +l+++ + + +el+ek+
  EEA20798.1 141 IREGLTEKVNDLEEQLSSLRDEYNSAVsdnntqsntidglqralqeiqdarKQELRELVQSSDAQLEELREKL 213
                 69999***********999999999999999999999999999999999998888888888888888888775 PP

>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9  16.5    0.0057       3.3     114     230 ..      34     171 ..       5     177 .. 0.86
   2 ?    4.1   5.6     0.041        23     116     174 ..     195     272 ..     173     292 .. 0.55

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0057
        CorA 114 rlldeivdrlfellekleeeldeledel..edstkkeilrelaqlrrrlvklrralapnrevlkrlla....kaddkllddedkeylrdlldeler... 203
                   l e +++ +e+l++  ++++eled+    + +  e l ++a l++++ +    l+++r+   +l +    ++ ++l+++e   y+r   +e+++   
  EEA20798.1  34 SQLGERLKEDAEELSQARSRIEELEDQNsaLKAEVSENLTKIAGLEKDAREHSNELSNLRNRA-NLSQqnwqQEKEELIEQES--YIRAEFEEAKQamh 129
                 567777888899****************99**********************99999999999.5555444255555555555..88888888888*** PP

        CorA 204 ...............llemlealrerleslqdtyssllserl 230
                                l e+++ l e+l+sl+d+y+s +s ++
  EEA20798.1 130 nwevlameersiregLTEKVNDLEEQLSSLRDEYNSAVSDNN 171
                 *************************************99885 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.041
        CorA 116 ldeivdrlfellekleeeldeledel...................edstkkeilrelaqlrrrlvklrralapnrevl 174
                 l+e+v++ +++le+l e+l+++e++                    ++++ ke    + +lr+++v+l ++l+   + l
  EEA20798.1 195 LRELVQSSDAQLEELREKLQQVEKRAeeantdlkqaqteldrllpFEKEVKEKNLLIGKLRHEAVTLNDHLTKALRFL 272
                 344444444444444444444444444333311332333366666555555555556666666666666666666655 PP

>> LMP  LMP repeated region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   1.4      0.21   1.2e+02     125     153 ..       2      30 ..       1      33 [. 0.88
   2 ?    3.2   6.4      0.13        74      16      80 ..      29      95 ..      17     102 .. 0.78
   3 ?    6.1   1.2     0.017       9.9      13      67 ..     107     163 ..      95     179 .. 0.78
   4 ?    9.9   6.6    0.0011      0.66      25      89 ..     178     245 ..     163     268 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.21
         LMP 125 eeLkqaLakakaakeqvdnaakslkeqLn 153
                 e+L+q+L++++ +k+q++ + ++l e +n
  EEA20798.1   2 EALQQKLNESEDKKTQAETQFQKLLERVN 30 
                 579******************99988875 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.13
         LMP 16 iqkakkeLekeiqkanqalns..nntasmqsakssLdakvteitkkLekFnkdkeakFkeLeqtRkd 80
                ++  k++L + +++  ++l +    +++++  +s+L+a v+e   k+   +kd   + +eL + R+ 
  EEA20798.1 29 VNTIKSQLGERLKEDAEELSQarSRIEELEDQNSALKAEVSENLTKIAGLEKDAREHSNELSNLRNR 95
                4556777777777766666441156899*************************99999**9999885 PP

  == domain 3  score: 6.1 bits;  conditional E-value: 0.017
         LMP  13 DkeiqkakkeLekeiqkanqalnsnntasmq..sakssLdakvteitkkLekFnkdk 67 
                  +e+ +  + + +e ++a+qa+++ +   m+  s+++ L+ kv +++++L   + + 
  EEA20798.1 107 KEELIEQESYIRAEFEEAKQAMHNWEVLAMEerSIREGLTEKVNDLEEQLSSLRDEY 163
                 4556666677889999******99999988644899**************9887665 PP

  == domain 4  score: 9.9 bits;  conditional E-value: 0.0011
         LMP  25 keiqkanqalnsnntasmqsakssLdakvteitkkLekFnkdkeakFkeLeqtRkdieeFl...kdvk 89 
                 + +q+a q+++   +++++ + +s da++ e+++kL++ +k  e    +L+q   +++  l   k+vk
  EEA20798.1 178 DGLQRALQEIQDARKQELRELVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQTELDRLLpfeKEVK 245
                 56799*****************************************************9985423333 PP

>> FH2  Formin Homology 2 Domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   6.2       3.5     2e+03     279     341 ..       2      68 ..       1      74 [. 0.55
   2 ?    5.3   5.6     0.016         9     261     345 ..      83     167 ..      64     178 .. 0.83
   3 ?   14.5   3.8   2.5e-05     0.014     254     368 ..     181     294 ..     170     296 .. 0.64

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 3.5
                 HHHHHHHHHHHHHHHHHHHHHHHCCT.....TSSTT-THHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
         FH2 279 eslekevkklekglkklekelessek.....keepsdkflevlkeflkeaeeklkkleeelkeakelv 341
                 e+l++++++ e++  ++e+++++  +     k++  ++++e  +  l++a++++++le++ + +k++v
  EEA20798.1   2 EALQQKLNESEDKKTQAETQFQKLLErvntiKSQLGERLKEDAE-ELSQARSRIEELEDQNSALKAEV 68 
                 56666666666666666666666655533333333333333333.35666666666666666666655 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.016
                 GGHHHHTTTHHHCCTS-HHHHHHHHHHHHHHHHHHHHHHHHCCTTSSTT-THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
         FH2 261 ldfsseLknvkkaakvnleslekevkklekglkklekelessekkeepsdkflevlkeflkeaeeklkkleeelkeakelvkelv 345
                  + s+eL+n++  a+++ ++ ++e ++l ++ + ++ e+e+ +++ ++++ +    +++ +  +ek+++lee+l++++++++++v
  EEA20798.1  83 REHSNELSNLRNRANLSQQNWQQEKEELIEQESYIRAEFEEAKQAMHNWEVLAMEERSIREGLTEKVNDLEEQLSSLRDEYNSAV 167
                 55689***************************************66666666666666666667888888888888888887765 PP

  == domain 3  score: 14.5 bits;  conditional E-value: 2.5e-05
                 HTTSGGGGGHH.HHTTTHHHCCTS-HHHHHHHHHHHHHHHHHHHHHHHHCCTTSSTT-THHHHHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHT CS
         FH2 254 reklpevldfs.seLknvkkaakvnleslekevkklekglkklekelessekkeepsdkflevlkeflkeaeek...lkkleeelkeakelvkelveYf 348
                 +++l+e++d   +eL+++ +++  +le+l+++++++ek+ ++++++l++ ++        l+ l +f ke +ek   + kl+ e  ++++ ++++++++
  EEA20798.1 181 QRALQEIQDARkQELRELVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQT-------ELDRLLPFEKEVKEKnllIGKLRHEAVTLNDHLTKALRFL 272
                 3455555555445666666666666666666666666666666666666655.......6677777777777763336677777777777888888888 PP

                 ..T--TTCCHHHHHHHHHHHHH CS
         FH2 349 ..gedkkevspeeffkilreFl 368
                   g+ +++v +  +++ l +Fl
  EEA20798.1 273 krGKPEDNVDRHVVTNHLLHFL 294
                 7655555888888998888887 PP

>> EzrA  Septation ring formation regulator, EzrA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6  39.7      0.11        62      58     302 ..       4     248 ..       1     266 [. 0.76

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.11
                 THHHHHHHHHHHHHHHHHHTHHHHHT-GGGT--S-SHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHTHHHHTTTTTHHHHHHHHHHHHHHHHT--TTT CS
        EzrA  58 seekfeewkkkwdeiktkklpeieellfeaeelldkykfkkakkklaeleeeldeveekikkileelkelteseeknreeieklkekYrelrkkllanr 156
                 +++k++e + k  + +t +++++ e+++ ++ +l   ++k+  ++l++++++++e+e +  ++++e++e +++    ++   +  ++  +lr++ +  +
  EEA20798.1   4 LQQKLNESEDKKTQAET-QFQKLLERVNTIKSQLG-ERLKEDAEELSQARSRIEELEDQNSALKAEVSENLTKIAGLEKDAREHSNELSNLRNRANLSQ 100
                 56666666666666555.78888888888877764.477777788888888888888888888777777777777777777777777778888888888 PP

                 THHHHHHHHHHHHHHHH----------------HHH..HHHHHHHHHHHHHHHHHHHHHHHHHTTTTTTSHHHHHHHHHHHHHSTTS--SGGGSSSSSH CS
        EzrA 157 fsygealeelekqleniekefsefeeltengdyvea..keilkkleeeideleevieeiPelleelkkelpkqleelkegykemkeegYaleelnieke 253
                 ++ ++ +eel +q + i  ef+e ++++ n + ++   + i + l e++++lee++  + + ++ + ++   q + +    + ++e + +  ++++ + 
  EEA20798.1 101 QNWQQEKEELIEQESYIRAEFEEAKQAMHNWEVLAMeeRSIREGLTEKVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQEIQ-DARKQELREL 198
                 8888888888888888888888888888888887551156889999999999999999999999999999999988876666666555.6677799999 PP

                 HHHHHHHHHHHHHHHTT-..-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        EzrA 254 ieelekkieeilerlkel..eledveeelktieeeidsLyddlekEveAkk 302
                 +++ ++++ee+ e+l+++  + e+++ +lk+ ++e+d L   +ekEv+ k+
  EEA20798.1 199 VQSSDAQLEELREKLQQVekRAEEANTDLKQAQTELDRLL-PFEKEVKEKN 248
                 9999999999999999883347889999999999999997.5999998776 PP

>> XhlA  Haemolysin XhlA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   1.6     0.017       9.7      15      47 ..       3      35 ..       1      37 [. 0.91
   2 ?    3.8   2.5      0.11        66       8      46 ..      39      80 ..      38      83 .. 0.77
   3 ?    1.3   0.2       0.7     4e+02      19      40 ..      74      95 ..      67     104 .. 0.79
   4 ?    4.1   0.9     0.092        53       3      46 ..     146     189 ..     144     192 .. 0.90
   5 ?   11.0   3.9   0.00065      0.38       2      44 ..     195     237 ..     194     238 .. 0.91

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.017
        XhlA 15 nleervdkleekaaeaeekiknleedlkklesn 47
                 l++++++ e+k++ ae++ + l e+++ ++s+
  EEA20798.1  3 ALQQKLNESEDKKTQAETQFQKLLERVNTIKSQ 35
                578999************************997 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.11
        XhlA  8 rietkldnlee...rvdkleekaaeaeekiknleedlkkles 46
                r++++ ++l++   r+++le+ ++  ++++ ++  +++ le+
  EEA20798.1 39 RLKEDAEELSQarsRIEELEDQNSALKAEVSENLTKIAGLEK 80
                677777788888778999999888888888888888777765 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.7
        XhlA 19 rvdkleekaaeaeekiknleed 40
                ++  le++a+e+ +++ nl ++
  EEA20798.1 74 KIAGLEKDAREHSNELSNLRNR 95
                4777999999999999998876 PP

  == domain 4  score: 4.1 bits;  conditional E-value: 0.092
        XhlA   3 kerlerietkldnleervdkleekaaeaeekiknleedlkkles 46 
                  e+++ +e++l +l ++ +    +++++ + i+ l+  l ++++
  EEA20798.1 146 TEKVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQEIQD 189
                 599*************9999999999999999999999999987 PP

  == domain 5  score: 11.0 bits;  conditional E-value: 0.00065
        XhlA   2 ikerlerietkldnleervdkleekaaeaeekiknleedlkkl 44 
                 ++e ++  +++l++l e+++++e++a+ea + +k+++ +l++l
  EEA20798.1 195 LRELVQSSDAQLEELREKLQQVEKRAEEANTDLKQAQTELDRL 237
                 5677888899*****************************9987 PP

>> FlaC_arch  Flagella accessory protein C (FlaC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   2.0     0.074        43       2      36 ..       1      35 [.       1      42 [. 0.91
   2 ?    5.7   1.0     0.033        19       7      31 ..      45      69 ..      38      75 .. 0.76
   3 ?    0.8   0.1       1.2   6.8e+02       1      22 [.      74      95 ..      74     110 .. 0.82
   4 ?    9.6   0.6    0.0021       1.2       1      39 [.     148     186 ..     148     189 .. 0.93
   5 ?    3.5   2.2      0.16        92       4      37 ..     194     227 ..     191     238 .. 0.77

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.074
   FlaC_arch  2 idelEnklsklsteletvkkeneelsksveelken 36
                ++ l++kl++ + + + +++++++l + v+++k +
  EEA20798.1  1 MEALQQKLNESEDKKTQAETQFQKLLERVNTIKSQ 35
                6789****************************976 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.033
   FlaC_arch  7 nklsklsteletvkkeneelsksve 31
                ++ls+  +++e ++++n+ l+ +v 
  EEA20798.1 45 EELSQARSRIEELEDQNSALKAEVS 69
                6788888888888888888888875 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 1.2
   FlaC_arch  1 ridelEnklsklsteletvkke 22
                +i  lE++  ++s el+++++ 
  EEA20798.1 74 KIAGLEKDAREHSNELSNLRNR 95
                6778999999999999999975 PP

  == domain 4  score: 9.6 bits;  conditional E-value: 0.0021
   FlaC_arch   1 ridelEnklsklsteletvkkeneelsksveelkenVkd 39 
                 ++++lE++ls+l  e +++ ++n+  s++++ l++  ++
  EEA20798.1 148 KVNDLEEQLSSLRDEYNSAVSDNNTQSNTIDGLQRALQE 186
                 89******************************9988765 PP

  == domain 5  score: 3.5 bits;  conditional E-value: 0.16
   FlaC_arch   4 elEnklsklsteletvkkeneelsksveelkenV 37 
                 el + +++ + +le +++++++++k  ee + + 
  EEA20798.1 194 ELRELVQSSDAQLEELREKLQQVEKRAEEANTDL 227
                 6667778888888888888888888888776655 PP

>> VWA_2  von Willebrand factor type A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.5         1   5.9e+02      45      72 ..      68      95 ..      10     131 .. 0.68
   2 ?    8.3   1.1     0.006       3.5      54     106 ..     144     204 ..      90     205 .. 0.74
   3 ?    0.7   0.1       1.4   8.1e+02      28      62 ..     213     247 ..     195     287 .. 0.47

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 1
       VWA_2 45 fsdgpevlipltkdkakilnalrnleak 72
                +s++ +++++l+kd +++ n+l nl+ +
  EEA20798.1 68 VSENLTKIAGLEKDAREHSNELSNLRNR 95
                4556667777777777777777777654 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.006
       VWA_2  54 pltkdkakilnalrnleak........gggtnlaaaLqlarkalkkrrkgekrvivlitDg 106
                 +lt+  +++++ l +l+++        + ++n+ ++Lq a +++++ rk+e r++v  +D+
  EEA20798.1 144 GLTEKVNDLEEQLSSLRDEynsavsdnNTQSNTIDGLQRALQEIQDARKQELRELVQSSDA 204
                 456666666666666666666667669999*****************99998888877765 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 1.4
       VWA_2  28 veallkslpgdrvglvtfsdgpevlipltkdkaki 62 
                 ++++ k+  + +  l +  ++  +l+p++k  ++ 
  EEA20798.1 213 LQQVEKRAEEANTDLKQAQTELDRLLPFEKEVKEK 247
                 33333333333444444444444444444444444 PP

>> Fez1  Fez1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1  28.0       1.8     1e+03      39     145 ..      46     164 ..       1     176 [. 0.57
   2 ?    4.1  22.5     0.099        58      45     159 ..     108     228 ..     101     244 .. 0.65
   3 ?    8.4  12.7    0.0048       2.8      15      99 ..     180     268 ..     173     328 .. 0.73

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 1.8
        Fez1  39 qlrelrakleekeeeikeleesleektlelevcenelqrkkseaellrekvekleeelkelreelselsleeeeaalesdeakaqrqe........... 126
                 +l ++r+++ee e++++ l+++++e  +++  +e++ +++++e ++lr++++  ++++++ +eel e++   +  ++e +eak+  ++           
  EEA20798.1  46 ELSQARSRIEELEDQNSALKAEVSENLTKIAGLEKDAREHSNELSNLRNRANLSQQNWQQEKEELIEQE---SYIRAEFEEAKQAMHNwevlameersi 141
                 455566667777777777777777777777777777777777777777777777777777777776633...223334444443333333444443222 PP

        Fez1 127 ....aeeleelkreverlraeLk 145
                     +e++++l++++  lr e +
  EEA20798.1 142 reglTEKVNDLEEQLSSLRDEYN 164
                 33334444444444444444444 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.099
        Fez1  45 akleekeeeikeleesleektlelevcenelqrkkseaellrekvekleeelkelreelselsleeeeaa..........lesdeakaqrqeaeeleel 133
                 ++l e+e+    +++++ee ++ +++ e    +++s  e l ekv+ lee+l++lr+e++++ +++++++          +e ++a++q+ + e +++ 
  EEA20798.1 108 EELIEQESY---IRAEFEEAKQAMHNWEVLAMEERSIREGLTEKVNDLEEQLSSLRDEYNSAVSDNNTQSntidglqralQEIQDARKQELR-ELVQSS 202
                 344444444...444555555555555555555567788999***************99987766555556888888765555555544444.678888 PP

        Fez1 134 kreverlraeLkeerqkkeeqassFe 159
                 ++++e+lr++L++ +++ ee +++ +
  EEA20798.1 203 DAQLEELREKLQQVEKRAEEANTDLK 228
                 89999999999888888777655544 PP

  == domain 3  score: 8.4 bits;  conditional E-value: 0.0048
        Fez1  15 LKqQLkdsqaevtqklseival.kaqlrelrakleekeeeikeleesleektlelevc...enelqrkkseaellrekvekleeelkel 99 
                 L   L+++q    q l e+v+   aql elr+kl++ e++++e+++ l++ ++el+++   e+e+++k+     lr ++ +l++ l++ 
  EEA20798.1 180 LQRALQEIQDARKQELRELVQSsDAQLEELREKLQQVEKRAEEANTDLKQAQTELDRLlpfEKEVKEKNLLIGKLRHEAVTLNDHLTKA 268
                 677899*************9862699************************999998853447888877555555555444444444333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (405 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3289  (0.183446); expected 358.6 (0.02)
Passed bias filter:                      889  (0.0495845); expected 358.6 (0.02)
Passed Vit filter:                       243  (0.0135535); expected 17.9 (0.001)
Passed Fwd filter:                       161  (0.00897987); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              31  [number of targets reported over threshold]
# CPU time: 2.15u 0.39s 00:00:02.54 Elapsed: 00:00:00.65
# Mc/sec: 1869.78
//
Query:       EEA20799.1  [L=205]
Description: DUF814 domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.3e-32  111.4   0.1    9.5e-32  109.9   0.1    1.8  1  NFACT-R_1  NFACT protein RNA binding domain
     0.0049   16.6   0.0     0.0093   15.7   0.0    1.4  1  TBCC       Tubulin binding cofactor C
  ------ inclusion threshold ------
      0.032   13.1   8.0       0.04   12.8   8.0    1.2  1  NARP1      NMDA receptor-regulated protein 1
        5.6    5.7   4.5        6.4    5.6   4.5    1.1  1  LMBR1      LMBR1-like membrane protein


Domain annotation for each model (and alignments):
>> NFACT-R_1  NFACT protein RNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  109.9   0.1   2.1e-35   9.5e-32       1     109 []       1     104 [.       1     104 [. 0.94

  Alignments for each domain:
  == domain 1  score: 109.9 bits;  conditional E-value: 2.1e-35
   NFACT-R_1   1 kvfwFk...ssdgylvimGkDkqeneelikkyleesdvwfhvdkessahvylrlsege.leeipeelleeaaqlakanSiagnklssvdvvyvpasnls 95 
                 +v++F     s   ++++GkDk+eneelik++le  dv        +ahvylrl+ege +e+ip+e+le++aql+kanSi+gnk+++++v+y+p+ nl 
  EEA20799.1   1 MVYYFVsnvVSPAATIYVGKDKFENEELIKHGLES-DV--------CAHVYLRLREGEtWENIPKEVLEDCAQLTKANSIEGNKKDNITVIYTPWANLM 90 
                 9*****6666666********************99.74........699*******999**************************************** PP

   NFACT-R_1  96 ktapldtGsvgfkg 109
                 k+a+++tG+v+f++
  EEA20799.1  91 KNASMATGQVSFHN 104
                 ************97 PP

>> TBCC  Tubulin binding cofactor C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   2.1e-06    0.0093      53     108 ..      94     150 ..      91     159 .. 0.88

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 2.1e-06
                 E---SEEEEES-BS-.EEE---SSEEEEES-BSEEEE------TTSHHHHHHHT--S CS
        TBCC  53 vvacrqlrihdctnv.dvylltksrPiiedskgirfapynlsypeleehlkkagldp 108
                 ++a+ q++ h+ ++v +v+++++++Pi+ + ++ r+ +++   +e ee lkk++ + 
  EEA20799.1  94 SMATGQVSFHNPKQVkKVFVAVRQNPIVNRLNKTRVEKFPDLQAEKEEILKKQRKEE 150
                 6899**********945******************************9999987665 PP

>> NARP1  NMDA receptor-regulated protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   8.0     9e-06      0.04     378     453 ..     107     177 ..      63     197 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 9e-06
                 HHHHHHHHHHH-TTGGG---HHHHHT-S-HHHHHHHHHHHHHHHHHHHHHHHHHHHHH--.......--------- CS
       NARP1 378 gaievYlkledkpkakeeekeeaksaelseaerkklrkkakkaekkaekeeaekaekekekkaaekkakkedeeak 453
                 +  +v++++  +p  ++ +k++ ++    +ae++ + kk++k+e++a+++++ +++ke++++++ k +k+     +
  EEA20799.1 107 QVKKVFVAVRQNPIVNRLNKTRVEKFPDLQAEKEEILKKQRKEERRAREDKKLAEKKERQERDQLKWQKE-----H 177
                 556899*******99999999888888889999*************999999977777665544333332.....2 PP

>> LMBR1  LMBR1-like membrane protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   4.5    0.0014       6.4     194     312 ..      71     193 ..      35     203 .. 0.71

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0014
       LMBR1 194 iksdldeelkklyfeaaklntekeeaerele.dllkevkklrksisesdplrkyleeilkkvPeeiaeklks..nenkteeslaklekqlikalqkrer 289
                 i+ ++++ +  +y+  a+l ++ + a+ +++ +  k+vkk+   ++++  + + +++ ++k+P   aek ++  +++ +ee+ a++ k+l ++ +++er
  EEA20799.1  71 IEGNKKDNITVIYTPWANLMKNASMATGQVSfHNPKQVKKVFVAVRQNPIVNRLNKTRVEKFPDLQAEK-EEilKKQRKEERRAREDKKLAEKKERQER 168
                 555556666666666666666655555555533446777777777777768889999999999955555.33688888999999999999999999999 PP

       LMBR1 290 tekqwkr..llekalelediiknks 312
                  + +w++  + +  +  e+++++++
  EEA20799.1 169 DQLKWQKehAYDDLFSEENLMQSNN 193
                 9999987446677766666665554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (205 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2330  (0.129957); expected 358.6 (0.02)
Passed bias filter:                      663  (0.0369792); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.47u 0.30s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 1443.76
//
Query:       EEA20800.1  [L=705]
Description: glycerol-3-phosphate dehydrogenase, mitochondrial [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.2e-50  170.3   0.0    1.2e-49  169.8   0.0    1.2  1  DAO            FAD dependent oxidoreductase
    1.5e-44  150.9   0.0    2.6e-44  150.1   0.0    1.4  1  DAO_C          C-terminal domain of alpha-glycerophosphate ox
    1.4e-08   34.2   0.0    2.8e-08   33.3   0.0    1.4  1  FAD_binding_2  FAD binding domain
     0.0003   20.3   0.3    0.00054   19.4   0.1    1.5  2  FAD_oxidored   FAD dependent oxidoreductase
     0.0018   17.6   0.0     0.0033   16.7   0.0    1.4  1  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
     0.0062   16.7   0.5      0.017   15.3   0.3    1.9  2  NAD_binding_8  NAD(P)-binding Rossmann-like domain
  ------ inclusion threshold ------
      0.013   15.4   0.2      0.026   14.4   0.2    1.5  1  3HCDH_N        3-hydroxyacyl-CoA dehydrogenase, NAD binding d
      0.036   12.8   0.3      0.063   12.0   0.3    1.3  1  HI0933_like    HI0933-like protein
      0.063   13.8   0.2       0.17   12.5   0.2    1.7  1  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
      0.091   12.0   0.1       0.23   10.7   0.0    1.6  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
      0.091   11.8   0.1        0.2   10.7   0.1    1.5  2  GIDA           Glucose inhibited division protein A


Domain annotation for each model (and alignments):
>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  169.8   0.0   7.2e-53   1.2e-49       1     352 []      89     460 ..      89     460 .. 0.81

  Alignments for each domain:
  == domain 1  score: 169.8 bits;  conditional E-value: 7.2e-53
                 EEEEECTSHHHHHHHHHHHHTT..EEEEESSSSTTSSGGGSSEEEEESSSSTHHSTH.....HHHHHHHHHHHHHHHHHHHHSSTTSEEEEEEEEEESS CS
         DAO   1 dvviiGGGiiGlstAyeLarrg..VtllekgdiagsgaSgrnsgllhsglrylpeas.....elarlslealeelreleeelgididyrrtGllslaad 92 
                 d+++iGGG +G+++A+++a+rg  V+++e++d+ + g+S+++++l+h+g+ryl++a      +++ l++eal+e++ + ++ ++++    + ++++   
  EEA20800.1  89 DLLVIGGGATGSGIALDAATRGlrVAVVERDDFSA-GTSSKSTKLVHGGVRYLEKAVweldyAQYSLVKEALRERKYFLKT-APHLSSWLPIMVPVQKW 185
                 789****************************5555.******************98899*99888**********999997.99988777888888643 PP

                 HHHHHHHHHHHHHH..........HHTTTTE.EEEEHHHHHHHSTTST..TTSEEEEETTEEEEEHHHHHHHHHHHHHHTT-EEEESECEEEEEEEE.T CS
         DAO  93 eeelealdkllall..........leaglda.elldaeevrelepalp..gllgalfypdtgqvdpakltaalaraaealGveilegtevtgleeed.g 177
                   + +++      +          ++ g+++ ++l+ +++++ +p+l+  +l ga++y+d+++ ++ ++  +la +a+  G +++++ evtgl ++  g
  EEA20800.1 186 W-QAPYF------WlgckaydflaGSEGIESsYFLTHSKALDAFPMLKkeDLFGAVVYYDGAH-NDSRMNVSLAMTAALYGSTVVNHLEVTGLTKDAsG 276
                 2.23332......022233455587799999458***99*******4446999*******666.*****************************554467 PP

                 CEEEEE....EECT.EEE.E..EEEE..EEE--GGGHHHH.HTT.CTTTSEEEEEEEEEEEEEECCTHSTGSGCSEEEEEEEETTTTEEEEEETTSEEE CS
         DAO 178 kvwgve....rttp.gen.d..aada..vVnaaGawsdll.gll.keldlpispvrgqvlvlkplseklvspaailpvpetdddgrgvyvtprkdgrvl 264
                 k+ g      ++++ g++ +   ++a  ++na+G++ d + +++ +e +  + p  g ++ l p   +++   +i+p   ++ dgr+++++p+  g+++
  EEA20800.1 277 KLNGALvkdlVAEKnGQEaKvfPIRAkgIINATGPFCDSIrKMDePETKDIVAPSSGVHVIL-PGYYSPSNMGLIDP---STSDGRVIFFLPWQ-GNTI 370
                 7777777888444446664367667788**********99888876666677**********.66665555557777...8899*********5.99** PP

                 EEESSEEETTCSSTSCSHHHHHHHHHHHHHHS.GGG....CGEEEEEEEEEEETTSSEEEEEEE.TEEEEEEEEECTTTHHHHHHHHHHHHHHH CS
         DAO 265 vGgtadeesgdddpevdeedidellealrklf.Pql....gdvlrkwaGlrplpdglpligetp.gvkglylatGhsghGltlapatGkllael 352
                 +G+t+  +  + +p++deedid++l++++ ++ P++    +dvl +w+G+rpl  ++p   +t+  v+++++   +  +Gl ++++ Gk+++++
  EEA20800.1 371 AGTTDRATQITAHPQPDEEDIDWILNEISGYLaPDInvrrEDVLAAWSGIRPL-VRDPKAKNTEsLVRNHLITISA--SGLLTCAG-GKWTTYR 460
                 ****9633344448******************888445568899********5.4456666654568888888555..9*******.***9986 PP

>> DAO_C  C-terminal domain of alpha-glycerophosphate oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  150.1   0.0   1.6e-47   2.6e-44       1     126 []     503     630 ..     503     630 .. 0.97

  Alignments for each domain:
  == domain 1  score: 150.1 bits;  conditional E-value: 1.6e-47
                 --TTS---TT--.......TT-STTHT--HHHHHHHHHHHGGGHHHHHHHHHHTH.....HHHHHTTS-HHHHHHHHHHHHHS---SHHHHHHTTS-HH CS
       DAO_C   1 crTkklpLvGaenwsknlaaelaqeygldeevaehLaerYGsraeevlelakedekp..elaerlspelpyieaevvYavrhEmartlvDvlaRRtrla 97 
                 c+T++++L+Ga+++sk+l+++l+q++g++++va+hL  +YG+ra++v++l++ ++++    ++r+sp +p+i +e++YavrhE+a+t+vDvlaRRtrla
  EEA20800.1 503 CQTHQVRLIGAHGYSKTLFINLIQHFGIETDVAKHLTISYGDRAWQVAALSSPTAARfpVRGTRVSPLYPFIDGEIRYAVRHEYAQTAVDVLARRTRLA 601
                 9***********************************************998888877889*************************************** PP

                 HH-HHHHHHHHHHHHHHHHHHTT--HHHH CS
       DAO_C  98 fldadaalealpevaelmaeelgWdearr 126
                 fl+a+aalealp v++lmaeel+Wde+r+
  EEA20800.1 602 FLNAQAALEALPSVIDLMAEELKWDEKRK 630
                 **************************986 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.3   0.0   1.7e-11   2.8e-08       1     209 [.      89     318 ..      89     334 .. 0.71

  Alignments for each domain:
  == domain 1  score: 33.3 bits;  conditional E-value: 1.7e-11
                    SEEEE--SHHHHHHHHHHHHTTT-EEEEESSSGGGSGGGG--S-EE-TT..SSGGSTC.CHHHHHHHHHHHHTTT-S-HHHHHHHHHTHHHHHHHH CS
  FAD_binding_2   1 DviViGsGlAGLaAAleaaeaGlkvavvekeqefggatawsqGgidavlspeqkkagikdspelhrtdtlkaldeladqplveafveaapeavdeL 96 
                    D++ViG+G+ G   Al aa +Gl+vavve  +   g++  s   +        + +   ++ ++ + +++ +l ++a  +  ++f+++ap+  ++L
     EEA20800.1  89 DLLVIGGGATGSGIALDAATRGLRVAVVERDDFSAGTSSKSTKLVHGGV----RYL---EKAVWELDYAQYSLVKEAL-RERKYFLKTAPHLSSWL 176
                    89******************************97776666643333333....111...2345555555555554433.33699************ PP

                    HHT.......T----B..........CCTSSB-EEE-TT-SST..............EEEE-.STT-......HHHHHHHHHHHHHHTCTEEEEES CS
  FAD_binding_2  97 eel.......gvpfsr..........tedgpvdvrelGglsat..............artlhdaadarretlvtghallarlvesarkagvdfqer 161
                      +        +p+++             + +  + + ++s+               a       ++  +  ++  ++ + l+ +a  +g ++ ++
     EEA20800.1 177 PIMvpvqkwwQAPYFWlgckaydflaG-SEGIESSYFLTHSKAldafpmlkkedlfgA------VVY-YDGAHNDSRMNVSLAMTAALYGSTVVNH 264
                    988887666655555577777776641.225555555555555666666664444432......333.2445578888888888888899****** PP

                    EEEEEEEEC.TTEEEEEEEEET......TTTCEEEEEESEEEE-----GG..... CS
  FAD_binding_2 162 teadeLive.dgrvtGavvenp......esgrevrirakavvlatgGfgrallke 209
                    +e++ L+ + +g+ +Ga v+++      ++ + + irak+++ atg f    +++
     EEA20800.1 265 LEVTGLTKDaSGKLNGALVKDLvaekngQEAKVFPIRAKGIINATGPFCD-SIRK 318
                    ******997456********99***988888889************9994.5544 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.1   3.3e-07   0.00054       1      40 [.      89     128 ..      89     168 .. 0.90
   2 ?   -3.8   0.0       3.6   5.9e+03     100     144 ..     257     310 ..     240     310 .. 0.62

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 3.3e-07
  FAD_oxidored   1 DvvVvGGgpaGvaAAiaAaraGakvlLveergvlGGllts 40 
                   D++V+GGg+ G   A+ Aa +G +v++ve++++  G++++
    EEA20800.1  89 DLLVIGGGATGSGIALDAATRGLRVAVVERDDFSAGTSSK 128
                   99******************************99888876 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 3.6
  FAD_oxidored 100 agvtvllntrlvevekeg....kr..iesvtveske.g..rktirAkvfiDATg 144
                   +g tv+ + ++++ +k+     +   ++ +++e++  +     irAk +i ATg
    EEA20800.1 257 YGSTVVNHLEVTGLTKDAsgklNGalVKDLVAEKNGqEakVFPIRAKGIINATG 310
                   566777777777777753224411357777776655444466789999999986 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0     2e-06    0.0033       1      39 [.      88     125 ..      11     159 .. 0.68

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 2e-06
                  CSEEEE--SHHHHHHHHHHHHHTS-EEEEETTHCHHHCS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2   1 kdvvviGgGpAGlaaaltlaqagakvtlvelegtclngg 39 
                  +d++viGgG+ G   al++a+ g++v++v +++ +  g+
   EEA20800.1  88 YDLLVIGGGATGSGIALDAATRGLRVAVV-ERDDFSAGT 125
                  35566666666666666666666666666.444444444 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.3   1.1e-05     0.017       1      44 [.      92     138 ..      92     161 .. 0.78
   2 ?   -3.2   0.0       6.4     1e+04      31      42 ..     452     464 ..     450     478 .. 0.72

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 1.1e-05
                    EE--SHHHHHHHHHHHCCTEEEEEE-SSSSSSGGG-EECE...TTCE CS
  NAD_binding_8   1 IvGaGlsGlvaAylLakagfdvlllekrdrlGGraasyev...pgvr 44 
                    ++G+G++G+ +A  +a +g++v ++e+ d   G ++  +    +gvr
     EEA20800.1  92 VIGGGATGSGIALDAATRGLRVAVVERDDFSAGTSSKSTKlvhGGVR 138
                    8**************************99877766655433544444 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 6.4
                    SSGGG-EECE.TT CS
  NAD_binding_8  31 lGGraasyev.pg 42 
                     GG++++y+   +
     EEA20800.1 452 AGGKWTTYRQmAE 464
                    6999999987434 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.2   1.6e-05     0.026       4      35 ..      92     123 ..      89     144 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.6e-05
                 EE--SCCHHHHHHHHHHTT-EEEEE-S-HHHH CS
     3HCDH_N   4 viGaGtmGagiaavfasagleVvlvdiseeal 35 
                 viG G  G+gia  +a +gl+V +v++++ ++
  EEA20800.1  92 VIGGGATGSGIALDAATRGLRVAVVERDDFSA 123
                 9*************************987555 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.3   3.9e-05     0.063       2      32 ..      89     119 ..      88     124 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 3.9e-05
                  SEEEE--SHHHHHHHHHHHHTT--EEEE-SS CS
  HI0933_like   2 dviviGgGaAGlmaAisaakrgkrVllleka 32 
                  d++viGgGa G   A+ aa+rg rV+++e+ 
   EEA20800.1  89 DLLVIGGGATGSGIALDAATRGLRVAVVERD 119
                  789*************************985 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.2    0.0001      0.17       2      32 ..      90     120 ..      89     128 .. 0.95

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.0001
                 EEEECSSHHHHHHHHHHHHTTSEEEEEESSS CS
   Pyr_redox   2 vvvvGgGyiglElAgalaelgkkVtvversd 32 
                 ++v+GgG +g   A  +a  g +V vver d
  EEA20800.1  90 LLVIGGGATGSGIALDAATRGLRVAVVERDD 120
                 69***************************87 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00014      0.23       1     197 [.      91     120 ..      80     165 .. 0.69
   2 ?   -3.5   0.0         3   4.9e+03     216     280 ..     465     531 ..     460     539 .. 0.62

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00014
  Pyr_redox_3   1 iIiGaGPaGlaaaielkkagledylilEkgnignsiyrypkemtfispsftsekleipdlnaiseetspafslkeeklsrkealeYlrevaksfelpi 98 
                  ++iG+G+ G ++a+ +   gl ++ ++E+                                                                     
   EEA20800.1  91 LVIGGGATGSGIALDAATRGL-RVAVVER--------------------------------------------------------------------- 118
                  355555555555555555555.4555555..................................................................... PP

  Pyr_redox_3  99 klfeeVesvkkedegfevetsketyeAkkviiAtGefdkPnklnipGeeklvkhyskvkefhkyagqkvvViGgknSavDaAlelvrkgaeVtvvtrg 196
                                                                                                                   +
   EEA20800.1 119 -------------------------------------------------------------------------------------------------D 119
                  .................................................................................................4 PP

  Pyr_redox_3 197 s 197
                  +
   EEA20800.1 120 D 120
                  4 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 3
  Pyr_redox_3 216 nrleelvkeekikvlfnaevkeikekeeeykvktedgkkvevkddvvlatGykpdl..sflkkslfe 280
                  + ++e++k  +++ ++ ++v +++ +  + +    dg+  + + + + a Gy+ +l  +++++ ++e
   EEA20800.1 465 EAVDEAIKGFSLQTHKVQDVPDVSGTGLKTDNFNLDGSCQTHQVRLIGAHGYSKTLfiNLIQHFGIE 531
                  5556666655567777777777777766666666676666667777777888777422555555555 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.1   0.00012       0.2       1      29 [.      89     117 ..      89     157 .. 0.82
   2 ?   -3.3   0.0       2.2   3.6e+03     139     154 ..     300     315 ..     290     323 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00012
                 CEEEE-SSHHHHHHHHHHHHTT--EEEEE CS
        GIDA   1 dviViGgGhAGceAAlaaarlGakvlLit 29 
                 d+ ViGgG  G+  Al aa +G++v+ + 
  EEA20800.1  89 DLLVIGGGATGSGIALDAATRGLRVAVVE 117
                 578***********************982 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 2.2
                 EEECEEEE--TT-BT- CS
        GIDA 139 ikakavviatGtflkg 154
                 i+ak ++ atG+f ++
  EEA20800.1 300 IRAKGIINATGPFCDS 315
                 6788999*****9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (705 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       382  (0.0213063); expected 358.6 (0.02)
Passed bias filter:                      360  (0.0200792); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.68u 0.29s 00:00:00.97 Elapsed: 00:00:00.47
# Mc/sec: 4495.46
//
Query:       EEA20801.1  [L=147]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-11   46.3  28.4      2e-11   45.4  28.4    1.4  1  Ecl1      ECL1/2/3 zinc binding proteins
     0.0042   16.8   0.3     0.0081   15.9   0.3    1.4  1  YacG      DNA gyrase inhibitor YacG
  ------ inclusion threshold ------
      0.079   12.8   0.1       0.13   12.1   0.1    1.2  1  MciZ      Mother cell inhibitor of FtsZ
        5.7    5.2  20.5          7    4.9  20.5    1.2  1  DUF515    Protein of unknown function (DUF515)


Domain annotation for each model (and alignments):
>> Ecl1  ECL1/2/3 zinc binding proteins
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.4  28.4   4.5e-15     2e-11       1     140 [.       3     131 ..       3     146 .. 0.42

  Alignments for each domain:
  == domain 1  score: 45.4 bits;  conditional E-value: 4.5e-15
        Ecl1   1 aasflqfCamCEkqivpsnsiLYCSEaCRrkDsekslssssssss......spplsprsssapseprdsavpsrp.sfsripsdssdsksdldptewks 92 
                 a++ l+fC++C++q+  s    YCS++CR++D  +  s ss ss+      +++ +p +ss       s+++sr+ ++sr p+ ++ s+s+ ++t+++ 
  EEA20801.1   3 ADWSLDFCLVCDQQT--SGAGPYCSQSCRLADLDQNASESSLSSYpvylssKSTIQPKTSSV------SSTQSRSsAVSRQPI-GKRSSSSFSSTSSN- 91 
                 6899***********..***************555554444443301111122333333333......444444422222222.22222222222222. PP

        Ecl1  93 rpasppspssssswnylstfpstsrsssss..ssesttsssstsssssss 140
                  ++s++ +s+ss+         ts ss++   s++ + s++  +  +++s
  EEA20801.1  92 -EQSSSLTSTSSQ---------TSLSSLTGtlSPSAALSNQVRHELQDYS 131
                 .111222211111.........1111111111111222233333333333 PP

>> YacG  DNA gyrase inhibitor YacG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.3   1.8e-06    0.0081      14      38 ..      16      40 ..      10      44 .. 0.82

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 1.8e-06
        YacG 14 eenpfrPFCSeRCkliDLGeWasee 38
                +++   P+CS+ C+l DL + ase+
  EEA20801.1 16 QTSGAGPYCSQSCRLADLDQNASES 40
                456677************9988886 PP

>> MciZ  Mother cell inhibitor of FtsZ
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.1   2.9e-05      0.13      18      36 ..     122     140 ..     121     140 .. 0.97

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 2.9e-05
                 HHHHHHHHHHHHXSBHHHH CS
        MciZ  18 EIRekLKeYgkqyetvkeW 36 
                 ++R+ L  Y+k ++ v +W
  EEA20801.1 122 QVRHELQDYSKSFDQVRDW 140
                 79***************** PP

>> DUF515  Protein of unknown function (DUF515)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9  20.5    0.0016         7     316     406 ..      51     137 ..      25     142 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.0016
      DUF515 316 sqsssvseesstsssessstsespGdvsisdsssasdsssvsqstseslsssisYsv.NLaeiLkAiaadkldasdevkaqlgnYGkellel 406
                 s+s+   ++ss ss++s+s++ s   +  + sss s++ss+ qs+s +++ss + s+  L++ L   aa     s++v+++l++Y k   ++
  EEA20801.1  51 SKSTIQPKTSSVSSTQSRSSAVSRQPIGKRSSSSFSSTSSNEQSSSLTSTSSQT-SLsSLTGTLSPSAA----LSNQVRHELQDYSKSFDQV 137
                 56777778899999999999999999999999999999*******999999988.5559*****99998....57899*******9887665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (147 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1437  (0.0801495); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.45u 0.28s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 1003.11
//
Query:       EEA20802.1  [L=123]
Description: DASH complex subunit DAD2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.7e-26   91.4   5.7      1e-25   90.0   5.7    1.7  1  DASH_Dad2       DASH complex subunit Dad2
  ------ inclusion threshold ------
      0.032   14.2   1.9       0.04   13.9   1.9    1.1  1  CENP-F_leu_zip  Leucine-rich repeats of kinetochore protein C
      0.058   13.1   1.5      0.067   12.9   1.5    1.2  1  PAXX            PAXX, PAralog of XRCC4 and XLF, also called C
       0.21   11.5   2.7        5.6    6.9   0.1    2.3  2  CAMSAP_CC1      Spectrin-binding region of Ca2+-Calmodulin
       0.59   10.6   3.7        7.9    7.0   1.0    2.4  2  NPV_P10         Nucleopolyhedrovirus P10 protein
       0.68   10.2   5.6       0.91    9.8   0.6    2.4  3  ABC_tran_CTD    ABC transporter C-terminal domain


Domain annotation for each model (and alignments):
>> DASH_Dad2  DASH complex subunit Dad2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.0   5.7   3.4e-29     1e-25       2      99 .]      28     114 ..      27     114 .. 0.87

  Alignments for each domain:
  == domain 1  score: 90.0 bits;  conditional E-value: 3.4e-29
   DASH_Dad2   2 ariaeKraELeaLkqlrdlsdslakqleeLeeklstladgteavasVlanWqnvlraismaslkllqkaeeeaeeeeedeeeeeeeeplpetLVRIpv 99 
                  ri++K+aELe+L qlrdls++la+q+++Le kl+tl+dgte++a+VlanWq+vl+ai+ma+ k +       ++ e+ +++    ++ p+tLVRIp+
  EEA20802.1  28 MRIEAKKAELENLTQLRDLSNALASQMQALELKLATLKDGTESIACVLANWQSVLQAINMATKKTA-------TSVEALATA----DSRPATLVRIPT 114
                 59*************************************************************986.......222222222....256999999996 PP

>> CENP-F_leu_zip  Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   1.9   1.3e-05      0.04      42     104 ..      25      90 ..      11     104 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.3e-05
  CENP-F_leu_zip  42 kvileaEtskaevet...lkeeieelaeelreleldLvalrsekeeLekelqkkqervseLeslns 104
                      +++  E +kae+e+   l++  + la++++ lel+L++l+   e+++  l ++q+  +  +++  
      EEA20802.1  25 TLTMRIEAKKAELENltqLRDLSNALASQMQALELKLATLKDGTESIACVLANWQSVLQAINMATK 90 
                     4556789999999994446667889**************************999986655555444 PP

>> PAXX  PAXX, PAralog of XRCC4 and XLF, also called C9orf142
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   1.5   2.2e-05     0.067      75     137 ..       5      68 ..       2      99 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.2e-05
                 -EEEEEETTEEEEEE-SSSS-EEEEE.EE--HHHHHHHHHHHHHHHHHHHHHHHHHHHTHHT-X CS
        PAXX  75 avsltlqedrasltlsggpsaLtleL.skledpeaaerlkaLllelAervaqlekrlaaveesa 137
                 +++ +l++++a+ t s+++ +Lt+ + +k  + e   +l++L   lA +++ le +la +++ +
  EEA20802.1   5 TINASLRQSNAYPTTSQQAMTLTMRIeAKKAELENLTQLRDLSNALASQMQALELKLATLKDGT 68 
                 567789999***************995688899*************************998754 PP

>> CAMSAP_CC1  Spectrin-binding region of Ca2+-Calmodulin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.1    0.0019       5.6      10      31 ..      17      38 ..       9      40 .. 0.81
   2 ?    4.8   0.3    0.0084        25       9      23 ..      47      61 ..      39      62 .. 0.88

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0019
  CAMSAP_CC1 10 selaselselrlkLEEKRRaIE 31
                +  + + ++l ++ E K+   E
  EEA20802.1 17 PTTSQQAMTLTMRIEAKKAELE 38
                5667899**********98877 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.0084
  CAMSAP_CC1  9 sselaselselrlkL 23
                s++las+++ l lkL
  EEA20802.1 47 SNALASQMQALELKL 61
                789***********9 PP

>> NPV_P10  Nucleopolyhedrovirus P10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   1.0    0.0026       7.9      18      62 ..      21      65 ..       6      78 .. 0.68
   2 ?    4.1   0.1     0.022        65       3      25 ..      79     101 ..      76     105 .. 0.92

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0026
     NPV_P10 18 dkVdalqqqvddvqenlpdvtelnekLdaqsaqLaeletkvenIq 62
                ++   l  +++  +++l+++t+l +  +a++ q+++le k+ + +
  EEA20802.1 21 QQAMTLTMRIEAKKAELENLTQLRDLSNALASQMQALELKLATLK 65
                555566666666667777777777777777777777766665544 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.022
     NPV_P10   3 qniLlvIradikavddkVdalqq 25 
                 q++L  I  + k++ + V+al +
  EEA20802.1  79 QSVLQAINMATKKTATSVEALAT 101
                 89*****************9976 PP

>> ABC_tran_CTD  ABC transporter C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.6    0.0003      0.91      27      61 ..       6      41 ..       4      43 .. 0.87
   2 ?    6.7   1.9    0.0029       8.6      20      56 ..      30      67 ..      29      79 .. 0.76
   3 ?    2.9   0.6     0.044   1.3e+02      13      28 ..      50      65 ..      42     109 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.0003
  ABC_tran_CTD 27 leaeladpely.sdpeklaelsaeleeleaeLeely 61
                  ++a l + + y +++++ + l+ ++e+ +aeLe+l+
    EEA20802.1  6 INASLRQSNAYpTTSQQAMTLTMRIEAKKAELENLT 41
                  678888888886888******************997 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0029
  ABC_tran_CTD 20 LEeeiaeleaeladpelysdp.eklaelsaeleeleae 56
                  +E+++aele+  +  +l +    ++++l  +l++l++ 
    EEA20802.1 30 IEAKKAELENLTQLRDLSNALaSQMQALELKLATLKDG 67
                  79999999998888887544367788888888888765 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.044
  ABC_tran_CTD 13 leaeIeaLEeeiaele 28
                  l ++++aLE ++a+l 
    EEA20802.1 50 LASQMQALELKLATLK 65
                  4455555555555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (123 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1343  (0.0749066); expected 358.6 (0.02)
Passed bias filter:                      656  (0.0365888); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 866.78
//
Query:       EEA20803.1  [L=659]
Description: shugoshin family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.5e-16   59.9   7.3    3.7e-16   58.7   3.6    2.5  2  Shugoshin_N  Shugoshin N-terminal coiled-coil region
    1.5e-10   40.6   4.6    1.5e-10   40.6   4.6    2.5  2  Shugoshin_C  Shugoshin C terminus
  ------ inclusion threshold ------
      0.019   14.7   0.5      0.067   12.9   0.5    1.9  1  CCDC85       CCDC85 family
       0.02   15.2   0.2      0.055   13.8   0.2    1.8  1  Prok-TraM    Prokaryotic Transcriptional repressor TraM
       0.14   12.2   2.6       0.15   12.2   0.4    2.2  2  bZIP_2       Basic region leucine zipper
       0.18   11.9   4.0       0.65   10.1   3.9    2.1  1  Mod_r        Modifier of rudimentary (Mod(r)) protein
       0.38   11.0   3.7        1.3    9.3   1.0    2.4  2  HALZ         Homeobox associated leucine zipper
        1.8    8.4   3.4        2.1    8.2   1.0    2.4  2  DivIC        Septum formation initiator


Domain annotation for each model (and alignments):
>> Shugoshin_N  Shugoshin N-terminal coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.7   3.6   1.6e-19   3.7e-16       1      45 []      17      61 ..      17      61 .. 0.98
   2 ?    2.0   0.1     0.088     2e+02      18      33 ..      86     101 ..      84     101 .. 0.89

  Alignments for each domain:
  == domain 1  score: 58.7 bits;  conditional E-value: 1.6e-19
  Shugoshin_N  1 lKrkylrqNreLAKsNsalslkirelekevseLlsENlnLRelil 45
                 lKr+++rqNre+A+ Ns++sl+i+ le+e+s+Ll+EN +L+e+++
   EEA20803.1 17 LKRRFVRQNREIARVNSLQSLRIQGLEAELSHLLKENTALKEQVI 61
                 7******************************************96 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.088
  Shugoshin_N  18 alslkirelekevseL 33 
                  +l +k++el+k vseL
   EEA20803.1  86 KLAAKVSELNKLVSEL 101
                  5899*******99998 PP

>> Shugoshin_C  Shugoshin C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.6   4.6   6.8e-14   1.5e-10       1      24 [.     426     449 ..     426     449 .. 0.98
   2 ?   -3.2   0.8       3.4   7.6e+03       4      12 ..     571     579 ..     570     579 .. 0.64

  Alignments for each domain:
  == domain 1  score: 40.6 bits;  conditional E-value: 6.8e-14
  Shugoshin_C   1 gRpsRrarkvvsYKEPSLnsKMRR 24 
                  +RpsRrar +vsY+EP+L++KMRR
   EEA20803.1 426 SRPSRRARGAVSYAEPNLRDKMRR 449
                  6**********************9 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 3.4
  Shugoshin_C   4 sRrarkvvs 12 
                  +Rr+++++s
   EEA20803.1 571 RRRSTNPTS 579
                  566568876 PP

>> CCDC85  CCDC85 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.5     3e-05     0.067     114     155 ..      37      79 ..      19     104 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 3e-05
      CCDC85 114 qklkeLearqeellrenleLkelvllLdeekaa.gagarssid 155
                  +++ Lea+ ++ll+en++Lke v+ L ++  + +ag+  + +
  EEA20803.1  37 LRIQGLEAELSHLLKENTALKEQVISLTQDAEKyAAGRAFHKE 79 
                 36789********************999887774344433333 PP

>> Prok-TraM  Prokaryotic Transcriptional repressor TraM
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.2   2.5e-05     0.055      42     101 ..      48     106 ..      22     107 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2.5e-05
                 HHHHHHHHHHHCHHHSCHHHHTTSCHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHTSEE- CS
   Prok-TraM  42 rllaaaeavyeewvrasadekvseavleelqeeYveaqkeseaqqeelstlldaLGyvPk 101
                 +ll+++ a+ e+ + +++d++   a++++ ++e  + + +  a+ +el++l++ LG +P+
  EEA20803.1  48 HLLKENTALKEQVISLTQDAEKY-AAGRAFHKEIHQCKDKLAAKVSELNKLVSELGLIPE 106
                 56777777777877777777665.55666777777778899******************6 PP

>> bZIP_2  Basic region leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.4   6.6e-05      0.15      26      53 ..      38      65 ..      36      66 .. 0.93
   2 ?   -3.9   0.1       6.8   1.5e+04      29      43 ..      86     100 ..      84     101 .. 0.63

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 6.6e-05
                HHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_2 26 keeeleervkeLeeeNaqLrqkveqLek 53
                + ++le ++ +L +eN +L+++v +L++
  EEA20803.1 38 RIQGLEAELSHLLKENTALKEQVISLTQ 65
                789**********************998 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 6.8
                 HHHHHHHHHHHHHHH CS
      bZIP_2  29 eleervkeLeeeNaq 43 
                 +l+ +v eL++  ++
  EEA20803.1  86 KLAAKVSELNKLVSE 100
                 566677777776655 PP

>> Mod_r  Modifier of rudimentary (Mod(r)) protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   3.9   0.00029      0.65      31     110 ..      14      97 ..       2     116 .. 0.63

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00029
       Mod_r  31 lkeekeellaeneslaeknlslepeleelrselqekleelkelekefeekeqeldell..qkfspd..allarLqtavaeaeee 110
                 +++ k   + +n+++a+ n  +  +++ l +el+  l+e ++l++++  ++q+ +++   + f ++    +++L ++v+e +++
  EEA20803.1  14 IEALKRRFVRQNREIARVNSLQSLRIQGLEAELSHLLKENTALKEQVISLTQDAEKYAagRAFHKEihQCKDKLAAKVSELNKL 97 
                 556666666677777776666666777777777777777777777777777666555554555544334555555555555543 PP

>> HALZ  Homeobox associated leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   1.0   0.00059       1.3      17      40 ..      42      65 ..      40      68 .. 0.88
   2 ?    1.6   0.1      0.14   3.2e+02      27      41 ..      83      97 ..      75      99 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00059
        HALZ 17 LksdydsLkkenekLkaelqeLke 40
                L ++   L+ken +Lk ++ +L++
  EEA20803.1 42 LEAELSHLLKENTALKEQVISLTQ 65
                6777889***************86 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.14
        HALZ 27 enekLkaelqeLkek 41
                 ++kL a++ eL+++
  EEA20803.1 83 CKDKLAAKVSELNKL 97
                599*********986 PP

>> DivIC  Septum formation initiator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   1.0   0.00094       2.1      25      55 ..      38      68 ..      20      76 .. 0.84
   2 ?   -1.2   0.1      0.77   1.7e+03      24      50 ..      78      94 ..      67     102 .. 0.52

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.00094
                HHHHHHHHHHHHHHHHHHHHHHHCC-XXXXX CS
       DivIC 25 eiaalqaelaklkaeneeLeaevkdLksded 55
                 i+ l+ael  l +en +L+++v  L++d +
  EEA20803.1 38 RIQGLEAELSHLLKENTALKEQVISLTQDAE 68
                5788999999999999999999999987654 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.77
                HHHHHHHHHHHHHHHHHHHHHHHHCC- CS
       DivIC 24 qeiaalqaelaklkaeneeLeaevkdL 50
                +ei++ +++la          a+v++L
  EEA20803.1 78 KEIHQCKDKLA----------AKVSEL 94
                44444444444..........333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (659 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1435  (0.0800379); expected 358.6 (0.02)
Passed bias filter:                      529  (0.0295053); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.71u 0.32s 00:00:01.03 Elapsed: 00:00:00.48
# Mc/sec: 4133.57
//
Query:       EEA20804.1  [L=181]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.3e-25   87.3   5.0    1.3e-24   85.8   5.0    1.9  1  PPI_Ypi1     Protein phosphatase inhibitor
  ------ inclusion threshold ------
        0.3    9.3  10.3       0.29    9.4  10.3    1.2  1  CDC45        CDC45-like protein
       0.65    8.5  13.1       0.82    8.2  13.0    1.3  1  TFIIF_alpha  Transcription initiation factor IIF, alpha subun


Domain annotation for each model (and alignments):
>> PPI_Ypi1  Protein phosphatase inhibitor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.8   5.0   2.2e-28   1.3e-24       1      60 []      35     111 ..      35     121 .. 0.94

  Alignments for each domain:
  == domain 1  score: 85.8 bits;  conditional E-value: 2.2e-28
    PPI_Ypi1   1 vLrLrg.................eekkkkkkkskrrVrWeedvvDNEgmnkkksKiCCIyhkprefdesSsesssss 60 
                 +LrLrg                  e++ ++ + +rrVrW+e+vv+NEgm+kk+sK+CCIyh+pr++desSses+sss
  EEA20804.1  35 TLRLRGeshshvvtvgesartetPEQEAAEGSPSRRVRWDENVVNNEGMGKKSSKVCCIYHRPRAMDESSSESESSS 111
                 699999999999999999999988888899999************************************99999986 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4  10.3   4.8e-05      0.29     116     213 ..      83     176 ..      16     181 .] 0.62

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 4.8e-05
       CDC45 116 leeereayealeeeeesdeedeeeeeeddddeeeeeeeeedeedeeedeeeskkkrk.sksdeeeesddddersrkrrrsepsakklrrqlkkerrkye 213
                 + ++ ++++ + + + +      +e++++++++++++++++++d++ + +++  +r+   +d +++++d+++  +k rr++ps ++ +rq ++err  +
  EEA20804.1  83 MGKKSSKVCCIYHRPRAM-----DESSSESESSSSSDDSDTDDDNDMRARRRPARREgCGHDGHDHEHDHNHGIKKVRRKRPSPNAYERQPRNERRPTQ 176
                 444444444444444443.....2222222233333333333334444444444444456666666666666666667777788888888666655444 PP

>> TFIIF_alpha  Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2  13.0   0.00014      0.82     302     410 ..      52     165 ..      15     180 .. 0.58

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.00014
                  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..X..XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....XXXX CS
  TFIIF_alpha 302 kkseEeeekkeieqdedeeekeeekkeeegklskkkkkakklkkkkkekdkk..dSddeedsddsDideedsvslvkakKkkekkkeekvd...snes 394
                   +  E++e++  e + +   + +e+  ++++  kk  k     ++ +  d++  +S+++++sddsD+d+++ + + ++  ++e   +++ d   + + 
   EEA20804.1  52 SARTETPEQEAAEGSPSRRVRWDENVVNNEGMGKKSSKVCCIYHRPRAMDESssESESSSSSDDSDTDDDNDMRARRRPARREGCGHDGHDhehDHNH 149
                  45567777777777777777777777777788888888777666666666650055556666777777766644443333333322222221112222 PP

                  XXXXXXXXXXXXXXXX CS
  TFIIF_alpha 395 sagnsrparpspeqkd 410
                  +  + r +rpsp++ +
   EEA20804.1 150 GIKKVRRKRPSPNAYE 165
                  3345677777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       883  (0.0492498); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.29s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 1199.36
//
Query:       EEA20805.1  [L=1072]
Description: exportin KapK [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.6e-138  461.3   8.9   1.6e-138  461.3   8.9    3.0  3  CRM1_C         CRM1 C terminal
    1.9e-42  144.8  10.7    2.2e-41  141.4   6.4    3.9  4  Xpo1           Exportin 1-like protein
      8e-34  115.1   4.5      2e-33  113.9   3.6    2.3  2  CRM1_repeat_2  CRM1 / Exportin repeat 2
    3.3e-29  100.7   0.6    3.3e-29  100.7   0.6    2.7  3  CRM1_repeat_3  CRM1 / Exportin repeat 3
    2.5e-20   71.7   1.8    5.5e-20   70.6   1.8    1.6  1  CRM1_repeat    Chromosome region maintenance or exportin repe
    4.8e-12   45.6   0.1    2.1e-11   43.5   0.1    2.3  1  IBN_N          Importin-beta N-terminal domain
  ------ inclusion threshold ------
      0.016   15.1   5.8       0.09   12.7   0.0    4.3  6  DUF3385        Domain of unknown function (DUF3385)
       0.15   12.6   2.9         25    5.5   0.2    4.0  4  HD_assoc       Phosphohydrolase-associated domain


Domain annotation for each model (and alignments):
>> CRM1_C  CRM1 C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.3      0.67   1.5e+03     147     198 ..     110     160 ..      84     207 .. 0.60
   2 ?    1.2   0.3     0.072   1.6e+02     131     160 ..     546     575 ..     515     633 .. 0.85
   3 !  461.3   8.9  7.2e-142  1.6e-138       1     321 []     706    1029 ..     706    1029 .. 0.99

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.67
      CRM1_C 147 inkkcfkallklpseqfklvidsivwafkHterdvaetgLnillellknvee 198
                 +n   +++l +  +++  ++i+ i+ ++ Ht  +++e+ + il+ l ++v +
  EEA20805.1 110 LNLVLVSILKQEWPHNWPTFINEIISSC-HTSLSICENNMAILRLLSEEVFD 160
                 5555555555555555555666555433.56666666666666555555444 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.072
      CRM1_C 131 eeyPehrveFfellrainkkcfkallklps 160
                  +yP + + ++++l+ +++k f+ +++ ++
  EEA20805.1 546 GQYPRFLKAHWKFLKTVVNKLFEFMHETHE 575
                 579999999999999999999999987655 PP

  == domain 3  score: 461.3 bits;  conditional E-value: 7.2e-142
      CRM1_C    1 QlgkiyldllklyklvseliseavaaegeiatktpkvrllrtvkkeiLkLietyiekaedleevlnnlveplleavLvdYkknvpeardaevLsllt 97  
                  Q+g+iy+d+l++y++ s+lis+ava++g+iatktp+vr+lrt+kkeiLkLi+ty++ka+dle+v++n+v+plleavL dY++nvp+ar+aevL+++t
  EEA20805.1  706 QIGRIYHDMLNMYRASSQLISDAVASDGTIATKTPRVRGLRTIKKEILKLIDTYVQKADDLEMVNQNMVPPLLEAVLLDYNRNVPDAREAEVLNVMT 802 
                  9************************************************************************************************ PP

      CRM1_C   98 tlveklenlisdevpkileavfectldmikkdfeeyPehrveFfellrainkkcfkallklpseqfklvidsivwafkHterdvaetgLnillellk 194 
                  t+++kl+nl+ d+vp i+e+vfectl+mi+kdf+eyPehrv+Ff+ll+ain +cf+allkl+ +qfk+vids++wa kH++r+v++tgL+++lel++
  EEA20805.1  803 TIIHKLHNLMDDKVPVIMESVFECTLEMINKDFHEYPEHRVQFFKLLQAINLYCFPALLKLDGNQFKFVIDSCMWASKHDNREVENTGLTMCLELMN 899 
                  ************************************************************************************************* PP

      CRM1_C  195 nveekkkeaanqFyknyylsllkevlkvltDtdhksgfklqaelLaklirlvesgsikvpllee...eqvtsnkvflseyvvellsnaFpnlsqkqv 288 
                  n++e++ ++++ F++++yls+l++v++vltDtdhk+gfk+qa+lL +++++vesg+i++p++ +   +++tsnk+fl+eyv++ll++aF+nl++ q+
  EEA20805.1  900 NMAETDLQTSSIFFRQFYLSILQDVFFVLTDTDHKAGFKSQAMLLSRMFYFVESGKIQEPIYSPeqaPAGTSNKDFLQEYVASLLQSAFKNLQEIQI 996 
                  **************************************************************99888899*************************** PP

      CRM1_C  289 eafvvglfelandlkkfkehlrDflislkefsg 321 
                  ++fv glf+ ++d +kfk+hlrDflislkef+g
  EEA20805.1  997 KQFVIGLFAYNDDFTKFKTHLRDFLISLKEFAG 1029
                  *******************************85 PP

>> Xpo1  Exportin 1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  141.4   6.4   9.7e-45   2.2e-41       2     149 .]     104     248 ..     103     248 .. 0.97
   2 ?   -3.3   0.0       3.8   8.4e+03      94     135 ..     528     569 ..     515     584 .. 0.46
   3 ?    0.4   0.0      0.28   6.3e+02     103     136 ..     748     781 ..     722     797 .. 0.81
   4 ?    1.4   0.0      0.14     3e+02      70     111 ..     806     849 ..     798     856 .. 0.69

  Alignments for each domain:
  == domain 1  score: 141.4 bits;  conditional E-value: 9.7e-45
                 HHHHHHHHHHHHHHHHHHTTTTSTTHHHHHHHHHCT.HHHHHHHHHHHHHHHHHHHTSHTTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH CS
        Xpo1   2 kflrnklaealaelflqeypnnWpsffddllsllssspsglelllriLkvlpeEiadfsrskleqerrndlkdllrsnvqkilelllqileqsqskkqs 100
                 ++ +nkl+++l+ +++qe+p+nWp+f+++++s++++s+s +e+++ iL++l+eE++d+s++++++ ++++lk++++++++ i++l++++l++ ++    
  EEA20805.1 104 RAFLNKLNLVLVSILKQEWPHNWPTFINEIISSCHTSLSICENNMAILRLLSEEVFDYSQDQMTSTKAKNLKTTMTQEFSSIFQLCSEVLNTANQ---- 198
                 5789**************************************************************************************99997.... PP

                 HHHHHHHHHHHHHHTTTS-HHHHHTSCHHHHH.HHHCCSCCCHHHHHHHH CS
        Xpo1 101 selveavLkclsswvswidiglivnnpllnll.fqlLsdpelreaavecL 149
                 + l++a+L++l ++++wi++g+i+++p++n+l  ++L+ pe+r+ +++cL
  EEA20805.1 199 PALIKATLETLLRFLNWIPLGYIFETPIINTLlTRFLDAPETRNVTLKCL 248
                 9**************************9998879***************8 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 3.8
                 HHHCCHHHHHHHHHHHHHHHHTTTS-HHHHHTSCHHHHHHHH CS
        Xpo1  94 sqskkqsselveavLkclsswvswidiglivnnpllnllfql 135
                  + k++++ ++++++ +++++ +  +    + ++++n lf++
  EEA20805.1 528 KRGKDNKAVVASNIMYIVGQYPRFLKAHWKFLKTVVNKLFEF 569
                 333334455555555555555443333333333333333333 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.28
                 HHHHHHHHHHHHTTTS-HHHHHTSCHHHHHHHHC CS
        Xpo1 103 lveavLkclsswvswidiglivnnpllnllfqlL 136
                 + +++Lk +  +v+  d   +vn+++++ l++++
  EEA20805.1 748 IKKEILKLIDTYVQKADDLEMVNQNMVPPLLEAV 781
                 67899*********99999999999888776655 PP

  == domain 4  score: 1.4 bits;  conditional E-value: 0.14
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHCC..HHHHHHHHHHHHH CS
        Xpo1  70 ndlkdllrsnvqkilelllqileqsqskk..qsselveavLkcl 111
                 ++l++l++++v+ i+e+++++  ++ +k+  + +e   + +k l
  EEA20805.1 806 HKLHNLMDDKVPVIMESVFECTLEMINKDfhEYPEHRVQFFKLL 849
                 57899999997777777777766666665554466666665555 PP

>> CRM1_repeat_2  CRM1 / Exportin repeat 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.9   3.6   8.8e-37     2e-33       1      68 []     402     469 ..     402     469 .. 0.98
   2 ?   -2.7   0.0       2.1   4.6e+03       2      17 ..     914     929 ..     913     933 .. 0.85

  Alignments for each domain:
  == domain 1  score: 113.9 bits;  conditional E-value: 8.8e-37
  CRM1_repeat_2   1 rkqlYkeiLsqlrlvlierMakPeEVliveneeGeivretvkdtdtialYktmretLvyLthLdvedt 68 
                    rk++Y+e+Ls+lr+v+ie+M++PeEVliven+eGeivre+vk++dti+lYkt re+LvyLthLdv dt
     EEA20805.1 402 RKHKYQEVLSSLRTVMIEKMVRPEEVLIVENDEGEIVREFVKESDTIQLYKTTRECLVYLTHLDVVDT 469
                    799**************************************************************997 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 2.1
  CRM1_repeat_2   2 kqlYkeiLsqlrlvli 17 
                    +q+Y +iL+++  vl 
     EEA20805.1 914 RQFYLSILQDVFFVLT 929
                    789999**99999886 PP

>> CRM1_repeat_3  CRM1 / Exportin repeat 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.7   0.6   1.5e-32   3.3e-29       1      51 []     482     532 ..     482     532 .. 0.98
   2 ?   -2.6   0.0       2.8   6.3e+03      31      46 ..     557     572 ..     556     575 .. 0.82
   3 ?   -2.6   0.0       2.9   6.5e+03      32      46 ..     800     814 ..     794     815 .. 0.82

  Alignments for each domain:
  == domain 1  score: 100.7 bits;  conditional E-value: 1.5e-32
  CRM1_repeat_3   1 dgseWswnnlnkLCWAiGSISgamseedEkrfLvtvikdLLnLceekrgkd 51 
                    dg+eWsw+n+n+LCWAiGSISgam+ee+EkrfLvtvikdLL L+e+krgkd
     EEA20805.1 482 DGTEWSWANCNTLCWAIGSISGAMNEETEKRFLVTVIKDLLGLTEQKRGKD 532
                    799**********************************************98 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 2.8
  CRM1_repeat_3  31 rfLvtvikdLLnLcee 46 
                    +fL tv+++L++++ e
     EEA20805.1 557 KFLKTVVNKLFEFMHE 572
                    6999******998765 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 2.9
  CRM1_repeat_3  32 fLvtvikdLLnLcee 46 
                     + t+i +L nL++ 
     EEA20805.1 800 VMTTIIHKLHNLMDD 814
                    5789*******9986 PP

>> CRM1_repeat  Chromosome region maintenance or exportin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.6   1.8   2.5e-23   5.5e-20       2      37 .]     328     363 ..     327     363 .. 0.97

  Alignments for each domain:
  == domain 1  score: 70.6 bits;  conditional E-value: 2.5e-23
                  HHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHH CS
  CRM1_repeat   2 allaalqYLvkISeVedrEiFKICLEYWnkLvseLY 37 
                  +l +a++YL++IS+++drEiFKICLEYW+kLv+eLY
   EEA20805.1 328 YLTHAHFYLIRISQIDDREIFKICLEYWTKLVQELY 363
                  7999*******************************9 PP

>> IBN_N  Importin-beta N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.5   0.1   9.5e-15   2.1e-11       1      73 [.      26      91 ..      26      92 .. 0.98

  Alignments for each domain:
  == domain 1  score: 43.5 bits;  conditional E-value: 9.5e-15
                HHHHHHHHHCSTCHHHHHHHHHHCTTSHHHHHHHHHHHHHHHHHHHGGSCCCHCGSXHHHHHHHHHHHHHHHH CS
       IBN_N  1 AekqLkqlekqpgflsallqilanseselevRqlAalyLknlitkhWsdeeekqslpseekeqIrnnllnllg 73
                A+++L +++++p++++++ +il+ s+ + ++++l++++L   i  +W+       lp ++ + Irn+++nl++
  EEA20805.1 26 AQQSLTEFKQNPDAWLSVGEILQESSYS-QTKYLGLQVLDEVIMTRWK------VLPRDQCQGIRNFVVNLII 91
                89**************************.*******************......****************997 PP

>> DUF3385  Domain of unknown function (DUF3385)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       2.7   6.1e+03      94     154 ..      46     111 ..      42     119 .. 0.45
   2 ?   -4.2   0.0       6.1   1.4e+04     113     142 ..     116     146 ..      99     156 .. 0.62
   3 ?   -0.7   0.0      0.54   1.2e+03      23      42 ..     236     255 ..     222     300 .. 0.82
   4 ?   12.7   0.0     4e-05      0.09      74     149 ..     504     581 ..     439     591 .. 0.83
   5 ?    1.6   0.0      0.11   2.4e+02      96     140 ..     671     721 ..     637     729 .. 0.70
   6 ?   -2.4   0.0       1.7   3.9e+03     104     137 ..     794     827 ..     768     839 .. 0.69

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 2.7
     DUF3385  94 ilkdpslsshhaavveai....mnifktlglkcvp.fLdqiipallsvirtteesnlrefllqqLa 154
                 il+++s+s+ +   ++++    m+  k l   + + + + +++ +++  ++ e+ + +  +l++L+
  EEA20805.1  46 ILQESSYSQTKYLGLQVLdeviMTRWKVLPRDQCQgIRNFVVNLIIEHSKSEEKLKSERAFLNKLN 111
                 666666666555555444222244444444333330333344444444444444455555556664 PP

  == domain 2  score: -4.2 bits;  conditional E-value: 6.1
     DUF3385 113 nifktlglkc.vpfLdqiipallsvirttee 142
                 +i+k+       +f+++ii++  + ++ +e+
  EEA20805.1 116 SILKQEWPHNwPTFINEIISSCHTSLSICEN 146
                 4444322222245666777666666666655 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 0.54
     DUF3385  23 qsqsirrevikllGilGALD 42 
                 +  ++r+ ++k+l+ +G L 
  EEA20805.1 236 DAPETRNVTLKCLTEIGGLQ 255
                 4679999*********9885 PP

  == domain 4  score: 12.7 bits;  conditional E-value: 4e-05
     DUF3385  74 glspsneeyyptvvinaLlrilkdpslsshhaavveaimnifkt..lglkc.vpfLdqiipallsvirtteesnlrefl 149
                  + + +e  +  +vi+ Ll + +++  ++++a v + im+i+ +    lk   +fL+ ++++l++ +++t+e  ++++ 
  EEA20805.1 504 AMNEETEKRFLVTVIKDLLGLTEQKRGKDNKAVVASNIMYIVGQypRFLKAhWKFLKTVVNKLFEFMHETHE-GVQDMA 581
                 3456668999999*****************************984433555588**************9988.776665 PP

  == domain 5  score: 1.6 bits;  conditional E-value: 0.11
     DUF3385  96 kdpslsshhaavveaimnifktlglkcvp.......fLdqiipallsvirtt 140
                 +dps+  + +++++++ ni+kt    c +        + +i +++l++ r +
  EEA20805.1 671 QDPSIL-QDSETIKVVGNIMKTNVAACSSigtyfypQIGRIYHDMLNMYRAS 721
                 777777.567788888888888776776655664336666677777776655 PP

  == domain 6  score: -2.4 bits;  conditional E-value: 1.7
     DUF3385 104 haavveaimnifktlglkcvpfLdqiipallsvi 137
                  a+v++++++i+++l   +   ++ i+ ++++++
  EEA20805.1 794 EAEVLNVMTTIIHKLHNLMDDKVPVIMESVFECT 827
                 4566667777777766666666666666666654 PP

>> HD_assoc  Phosphohydrolase-associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.0     0.028        62       9      58 ..      77     126 ..      75     134 .. 0.85
   2 ?    5.5   0.2     0.011        25       7      43 ..     406     442 ..     403     456 .. 0.91
   3 ?   -3.8   0.0         8   1.8e+04      37      51 ..     561     575 ..     560     584 .. 0.77
   4 ?   -1.8   0.1       2.1   4.7e+03      14      73 ..     996    1054 ..     990    1055 .. 0.68

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.028
    HD_assoc   9 aeiaeLkkflfenvyrhpevqreeekarriireLfealledperllpeef 58 
                  +++ +++f+++ +++h++ +++ + +r  +++L  +l++  +++ p+++
  EEA20805.1  77 DQCQGIRNFVVNLIIEHSKSEEKLKSERAFLNKLNLVLVSILKQEWPHNW 126
                 68999*****************************9999886665666665 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.011
    HD_assoc   7 vaaeiaeLkkflfenvyrhpevqreeekarriireLf 43 
                 +++ +  L++++ e+++r +ev  +e+ + +i+re +
  EEA20805.1 406 YQEVLSSLRTVMIEKMVRPEEVLIVENDEGEIVREFV 442
                 6778899***************************977 PP

  == domain 3  score: -3.8 bits;  conditional E-value: 8
    HD_assoc  37 riireLfealledpe 51 
                  ++++Lfe+++e+ e
  EEA20805.1 561 TVVNKLFEFMHETHE 575
                 689999999888655 PP

  == domain 4  score: -1.8 bits;  conditional E-value: 2.1
    HD_assoc   14 LkkflfenvyrhpevqreeekarriireLfealledperllpeefrarleaaeddaraRv 73  
                  +k+f+      +++  + +++ r+ +  L e+  +++e l+ ee +++l++a+ ++r+R+
  EEA20805.1  996 IKQFVIGLFAYNDDFTKFKTHLRDFLISLKEFAGDNAE-LYAEEREQALQDAKAAERDRA 1054
                  66666666666666667777777777777777777777.777777777777777677775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1072 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1051  (0.0586201); expected 358.6 (0.02)
Passed bias filter:                      629  (0.0350828); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.88u 0.34s 00:00:01.22 Elapsed: 00:00:00.52
# Mc/sec: 6166.86
//
Query:       EEA20806.1  [L=696]
Description: acetyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    7.2e-85  283.9  10.8    7.2e-85  283.9  10.8    2.1  2  Mac_assoc  Unstructured region on maltose acetyltransferase
    2.6e-12   46.8   0.0    6.4e-12   45.5   0.0    1.6  1  Mac        Maltose acetyltransferase
    2.2e-10   40.1   4.9    1.1e-07   31.5   0.0    3.5  3  Hexapep_2  Hexapeptide repeat of succinyl-transferase
    6.9e-10   38.9   8.5    1.5e-09   37.8   8.5    1.6  1  Zn_clus    Fungal Zn(2)-Cys(6) binuclear cluster domain
    1.5e-08   34.0   5.6    0.00033   20.3   0.1    3.7  3  Hexapep    Bacterial transferase hexapeptide (six repeats)


Domain annotation for each model (and alignments):
>> Mac_assoc  Unstructured region on maltose acetyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.2         1   3.7e+03      60      82 ..     210     232 ..     157     256 .. 0.62
   2 !  283.9  10.8     2e-88   7.2e-85       1     185 []     311     497 ..     311     497 .. 0.99

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1
   Mac_assoc  60 aqyitsptgvsssrgsWskrsWs 82 
                 aq + + +  + s  s +++ W+
  EEA20806.1 210 AQLVEALQRETHSTDSMEQKPWP 232
                 23333333334444444455554 PP

  == domain 2  score: 283.9 bits;  conditional E-value: 2e-88
   Mac_assoc   1 kPsssktPvPLqsKegYsevgsqYlqevspq.hdrqqslaeqvdagKvRpivvddndraaaqyitsptgvsssrgsWskrsWsgtghtaylpdev.akp 97 
                 kPsssk+PvPLqsK+gYse+++qYlq+v+++ h+r q++a+q++ +KvRp+vv+dnd+aaaqy  +pt+v+++r++W krsW++++h++y+++++ +++
  EEA20806.1 311 KPSSSKGPVPLQSKDGYSEAANQYLQDVNARhHERIQTTAQQAEVNKVRPVVVEDNDNAAAQYLGTPTNVTGNRNAWPKRSWPSASHPPYMAEHMsKST 409
                 9****************************99899*************************************************************8889 PP

   Mac_assoc  98 dyRevpsihelsreeksKsdykvvpsirelshasshpKpglplfqggidqrpahpssvdtsspqaqARlALsiEhqlsaravsseetE 185
                 dyRevp+ihelsre+++K++y+vvpsirels++++hpKpg+p+fqg++dqrp hpss+dtsspqaqARlALsiEhqlsar+ ++e+tE
  EEA20806.1 410 DYREVPPIHELSREGQPKTEYHVVPSIRELSQQGPHPKPGMPMFQGAVDQRPPHPSSIDTSSPQAQARLALSIEHQLSARHNTGEDTE 497
                 ***************************************************************************************8 PP

>> Mac  Maltose acetyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.5   0.0   1.8e-15   6.4e-12       1      49 [.     500     551 ..     500     558 .. 0.89

  Alignments for each domain:
  == domain 1  score: 45.5 bits;  conditional E-value: 1.8e-15
                 HHHTTS-BETTTSHHHHHHHHHHHHHHHHHHT.STTT...-HHHHHHHHHHHS CS
         Mac   1 KMlaGelYdafsDpeLvaeRlrarelcrryNq.trps...dkdeRrelLrell 49 
                 KM+ GelY++f D +Lv++R r++ +++r+N+ + p      +e+++lLre++
  EEA20806.1 500 KMIHGELYRPF-DMQLVEDRDRCKSALWRFNNaCNPLsgvSSKEQNRLLREII 551
                 9*********6.8******************96644456688999******97 PP

>> Hexapep_2  Hexapeptide repeat of succinyl-transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0      0.36   1.3e+03      19      28 ..     570     579 ..     570     579 .. 0.90
   2 !    8.4   0.5   0.00051       1.8       1      32 [.     588     623 ..     588     624 .. 0.87
   3 !   31.5   0.0   2.9e-11   1.1e-07       1      32 [.     646     679 ..     646     681 .. 0.95

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.36
                 EE-TT-EE-T CS
   Hexapep_2  19 slGdncvvga 28 
                 s+G ++vv+a
  EEA20806.1 570 SIGQGAVVEA 579
                 69******98 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.00051
                 .EEE-TT-EE-TT-E.E...SEEE-TT-EE-TT-EE CS
   Hexapep_2   1 pviIGdnCliGanag.i...GvslGdncvvgaGvvi 32 
                 +++IG++++i  n+  +   ++++G    +g++v+i
  EEA20806.1 588 NIHIGEDVMISENCSmVddcPINIGAHTWIGPNVTI 623
                 589**********99547779****99999999998 PP

  == domain 3  score: 31.5 bits;  conditional E-value: 2.9e-11
                 .EEE-TT-EE-TT-EE..SEEE-TT-EE-TT-EE CS
   Hexapep_2   1 pviIGdnCliGanagi..GvslGdncvvgaGvvi 32 
                 pv+I+++C +Gan++i  Gv l++++ v++G v+
  EEA20806.1 646 PVTIEEDCYVGANCTIypGVRLRRGAYVAPGEVV 679
                 8******************************777 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.8   8.5   4.2e-13   1.5e-09       1      39 [.     271     309 ..     271     310 .. 0.94

  Alignments for each domain:
  == domain 1  score: 37.8 bits;  conditional E-value: 4.2e-13
                 SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus   1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfysesskr 39 
                 ++C +Cr++K KCd+++PaC nC++ ++ C+ ys +s++
  EEA20806.1 271 TGCLTCRRRKKKCDEQHPACNNCIRGGFVCEGYSSRSTW 309
                 58*******************************999876 PP

>> Hexapep  Bacterial transferase hexapeptide (six repeats)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.1   0.2    0.0056        20      19      32 ..     588     601 ..     570     605 .. 0.69
   2 !    9.2   0.2   0.00029         1       3      18 ..     610     625 ..     608     626 .. 0.88
   3 !   20.3   0.1   9.1e-08   0.00033       2      31 ..     647     676 ..     646     679 .. 0.94

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0056
                 TEEE-TTEEEETTE CS
     Hexapep  19 nVkIGdnvkIgagv 32 
                 n++IG++v I +++
  EEA20806.1 588 NIHIGEDVMISENC 601
                 67788888887776 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00029
                 EEETTEEE-TTEEEET CS
     Hexapep   3 vIGsnvlIgpfavigg 18 
                  IG +++Igp+++i+g
  EEA20806.1 610 NIGAHTWIGPNVTILG 625
                 79***********986 PP

  == domain 3  score: 20.3 bits;  conditional E-value: 9.1e-08
                 EEEETTEEE-TTEEEETTEEE-TTEEEETT CS
     Hexapep   2 tvIGsnvlIgpfaviggnVkIGdnvkIgag 31 
                 ++I++++++g++++i+++V + +++++++g
  EEA20806.1 647 VTIEEDCYVGANCTIYPGVRLRRGAYVAPG 676
                 79*************************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (696 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       769  (0.0428914); expected 358.6 (0.02)
Passed bias filter:                      329  (0.0183502); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.44
# Mc/sec: 4756.47
//
Query:       EEA20807.1  [L=376]
Description: porphobilinogen synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   4.6e-121  403.9   0.0   5.5e-121  403.6   0.0    1.1  1  ALAD      Delta-aminolevulinic acid dehydratase


Domain annotation for each model (and alignments):
>> ALAD  Delta-aminolevulinic acid dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  403.6   0.0  3.1e-125  5.5e-121       4     317 .]      54     373 ..      51     373 .. 0.97

  Alignments for each domain:
  == domain 1  score: 403.6 bits;  conditional E-value: 3.1e-125
                 GGGGGSSHHHHHHC-S----GGGEEEEEEEESS-SS-EE-TTSTT-EEEEGGGHHHHHHHHHHTT--EEEEEEE-...SS-BSS-GGGGSTTSHHHHHH CS
        ALAD   4 lrrlrksealrelvretrlsasdlilplfvkegeeekeeiksmpgvyrlsvdelvkeveelvklgikavllFgvp...eekdeegsealnedglvqrai 99 
                 l+  ++++  r++++e++l++++li+plf++++ +e+++i+s+p++ r ++++lv  ++ lv++g+++v+lFgvp   + kd+ g++a++++g+v +ai
  EEA20807.1  54 LHAGYSHPLARSWQAERQLTKEMLIYPLFITDNPDEETPIPSLPNQCRRGLNRLVPFLTPLVRKGLRSVMLFGVPlnpNAKDPLGTAADDPSGPVIQAI 152
                 6778899*******************************************************************975455******************* PP

                 HHHHHH-TTSEEEEEE-STTTBSS-SSSEE.ESS.EEHHHHHHHHHHHHHHHHHCT-SEEEE-S--TTHHHHHHHHHHHTT-.TT-EEB---EEB--CG CS
        ALAD 100 raikeevpelvvitDvclceytshGhcgil.eekevdndetlellakvavsqaeaGadivapSdmmDgrvaaireaLdeagf.eevailsYsaKyaSaf 196
                 r +++++p+l++++DvclceytshGhcgil ++++++n +++e++++va+++a aGa++vapSdm Dgrv+ai+ +L eag+ ++v ++sY+aK++ ++
  EEA20807.1 153 RLLRAQFPNLYITVDVCLCEYTSHGHCGILcDDGSLNNAQSVERISDVALAYAMAGAHCVAPSDMNDGRVRAIKLKLIEAGIsHQVLLMSYAAKFSGSL 251
                 ******************************66677**********************************************9889************** PP

                 GHHHHHHHT---S.S--TTTSB-TT-HHHHHHHHHHHHHTT-SBEEEES-TTGHHHHHHHHTT-.SS-EEEEE-HHHHHHHHHHHHTTSS-HHHHHHHH CS
        ALAD 197 YgPFrdaaesapsfgdrktYqmdpansrealreveldleeGADivmvKPalaylDiirevkeef.dlpvaayqvSGEYamikaaaengwldekkvvlEs 294
                 YgPFrdaa+sapsfgdrk+Yq++p  +  a r++ +d++eGADi+mvKPa  +lDii+++ke + d+p+aayqvSGE+ami+aaa++g++d k+++lEs
  EEA20807.1 252 YGPFRDAAGSAPSFGDRKCYQLPPGGRGLARRAIIRDVAEGADIIMVKPASNFLDIISDAKELAkDMPIAAYQVSGEFAMIHAAAKAGVFDLKEMALES 350
                 **************************************************************9989********************************* PP

                 HHHHHHTT-SEEEETTHHHHHH. CS
        ALAD 295 llsikRAGadliltYfakevakl 317
                 +++i RAGa ++++Yf++e++++
  EEA20807.1 351 TQGILRAGAGIVISYFTPEFLDW 373
                 *******************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (376 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       349  (0.0194657); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.30s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 2458.19
//
Query:       EEA20808.1  [L=125]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
       0.01   16.7   0.5      0.014   16.3   0.5    1.2  1  HABP4_PAI-RBP1  Hyaluronan / mRNA binding family


Domain annotation for each model (and alignments):
>> HABP4_PAI-RBP1  Hyaluronan / mRNA binding family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   16.3   0.5   7.5e-07     0.014      17      46 ..      38      70 ..      32     118 .. 0.60

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 7.5e-07
  HABP4_PAI-RBP1 17 neeKregagrgnWGtvkdeieeqeeeeae...k 46
                    n++K++g+g+gnWG + +e+++ + + ++    
      EEA20808.1 38 NKTKKDGGGKGNWGRSGEEVQDYDYNFTNarrR 70
                    679****************98876654433221 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (125 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       300  (0.0167327); expected 358.6 (0.02)
Passed bias filter:                      238  (0.0132746); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.24s 00:00:00.63 Elapsed: 00:00:00.41
# Mc/sec: 915.42
//
Query:       EEA20809.1  [L=74]
Description: hypothetical protein PMAA_046280 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (74 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       319  (0.0177924); expected 358.6 (0.02)
Passed bias filter:                      237  (0.0132188); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.39u 0.24s 00:00:00.63 Elapsed: 00:00:00.40
# Mc/sec: 550.39
//
Query:       EEA20810.1  [L=231]
Description: hypothetical protein PMAA_046290 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.018   14.8   0.1      0.025   14.3   0.1    1.2  1  DUF4300   Domain of unknown function (DUF4300)
      0.093   13.2   0.1       0.17   12.3   0.1    1.4  1  HsbA      Hydrophobic surface binding protein A


Domain annotation for each model (and alignments):
>> DUF4300  Domain of unknown function (DUF4300)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.1   2.8e-06     0.025       8      76 ..      41     108 ..      33     121 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2.8e-06
     DUF4300   8 kesqkevkkaLkeagiskknvdaflesVnefnktv.ekkellkkgfeklkkkkpkydevkiqdawekknk 76 
                 ++s +e+  ++ ++ i+  ++ +f++sV++f+++v +++  l+k ++ l  ++ + d+ +i d+++k++ 
  EEA20810.1  41 AKSAHEMLLYMGNQAIKDPTIFNFIRSVKNFANAVpKRDGELDKVWQAL--NSIQRDTAQIRDKVSKSST 108
                 567788888999***********************666778******77..8888999999999998775 PP

>> HsbA  Hydrophobic surface binding protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.1   1.9e-05      0.17      14      69 ..      67     120 ..      60     134 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.9e-05
                 HHHHHHHHHHH--SH..HHHHHHHHHHHHHHHHHHHHHHHTS----HHHHHHHHHH CS
        HsbA  14 avtaldtavnafnGgasalpilsasnalvsaikkattdaqasapltdeealalaqa 69 
                 +v+++ +av + +G   + ++++a n++++++ + ++++++s++ + ++++a+  +
  EEA20810.1  67 SVKNFANAVPKRDGE--LDKVWQALNSIQRDTAQIRDKVSKSSTSDSSDSAAIWRT 120
                 566777777777664..89*******************************999665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (231 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       657  (0.0366445); expected 358.6 (0.02)
Passed bias filter:                      460  (0.0256568); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.24s 00:00:00.65 Elapsed: 00:00:00.38
# Mc/sec: 1812.36
//
Query:       EEA20811.1  [L=234]
Description: hypothetical protein PMAA_046300 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00015   22.4   0.0    0.00027   21.6   0.0    1.3  1  zf-RVT    zinc-binding in reverse transcriptase


Domain annotation for each model (and alignments):
>> zf-RVT  zinc-binding in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.6   0.0   1.5e-08   0.00027      45      79 ..     138     172 ..     129     175 .. 0.89

  Alignments for each domain:
  == domain 1  score: 21.6 bits;  conditional E-value: 1.5e-08
      zf-RVT  45 ptadnllkrgiesssrCqlCgqeeEtieHlfleCp 79 
                 p+   l++ ++  s++C  Cg+  Et++H+++eC+
  EEA20811.1 138 PIGTYLHRIKARDSPECRACGELRETVSHILFECR 172
                 566779999999**********************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (234 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       350  (0.0195214); expected 358.6 (0.02)
Passed bias filter:                      282  (0.0157287); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.23s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1773.24
//
Query:       EEA20812.1  [L=519]
Description: pogo transposable element, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    9.5e-33  113.3   0.0      2e-32  112.2   0.0    1.6  1  DDE_1        DDE superfamily endonuclease
      5e-09   36.1   0.5    2.4e-08   33.9   0.0    2.2  2  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
    1.1e-05   25.1   0.0    2.8e-05   23.7   0.0    1.7  1  HTH_psq      helix-turn-helix, Psq domain


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.2   0.0   3.4e-36     2e-32       2     175 .]     204     373 ..     203     373 .. 0.95

  Alignments for each domain:
  == domain 1  score: 112.2 bits;  conditional E-value: 3.4e-36
       DDE_1   2 erltvllcanaagsekLkplvigkak.sprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrle..aekrkilLlldssrshetvel.les 95 
                 ++++++++a  +++  +++++i+kak + r  ++   ++ ++d+++ +++++w+t++i+ eWL  +f++ ++  + +++ +L+ld+++sh t+e+   +
  EEA20812.1 204 QEWVTAIEATNSTGWAIPSYIIFKAKkNVRLGWF---DDLPSDWRIDISENGWTTDQIGLEWLkTHFIPYINgrSMGSYRMLILDGHGSHLTAEFdRTC 299
                 7899********************9725677888...99*********************************99*********************9*** PP

       DDE_1  96 elqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                  ++ni  +++P++s++llqPld+g+++ lK++Y +q+ q + ++ n+++k       ld+l    +A++ a + +ti+++f
  EEA20812.1 300 TENNIIPICMPPHSSHLLQPLDVGCFAVLKRHYGQQVEQRMRHGFNHIDK-------LDFLMAFPQARTeAYTARTIQNSF 373
                 **************************************************.......999999999999899999999887 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.9   0.0     4e-12   2.4e-08       5      61 ..      73     125 ..      70     130 .. 0.91
   2 ?   -1.2   0.4      0.35   2.1e+03      14      35 ..     483     504 ..     481     514 .. 0.77

  Alignments for each domain:
  == domain 1  score: 33.9 bits;  conditional E-value: 4e-12
                  HHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT.S CS
  HTH_Tnp_Tc5   5 EkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh.g 61 
                  E++L++W+ +l++rg p++++l+r++ + l+     l++++++++k+W+ + +kR  +
   EEA20812.1  73 EDSLVKWVLDLDRRGLPPRHSLVRDMVNYLL-----LQHGKPQVGKNWVTNLIKRRpE 125
                  899**************************95.....6679***************854 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.35
                  HHC-CT---SCHHHHHHHHHHH CS
  HTH_Tnp_Tc5  14 qlrergipitgelirekAqela 35 
                  q  ++ i+i + + re+Aq+l 
   EEA20812.1 483 QKSKKQISIEQGITREEAQALV 504
                  44788999999999*****995 PP

>> HTH_psq  helix-turn-helix, Psq domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.7   0.0   4.7e-09   2.8e-05       5      41 ..      19      56 ..      15      59 .. 0.85

  Alignments for each domain:
  == domain 1  score: 23.7 bits;  conditional E-value: 4.7e-09
     HTH_psq  5 laaAleavvnGk.mSirkAArkYgiPrsTLwrrkrgky 41
                ++ A+ +  nG  + ir+A r+Y+iPr+TL+ r++g++
  EEA20812.1 19 IQFAISDLKNGRiLNIREATRIYDIPRTTLRDRLKGIE 56
                555666777999999********************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (519 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1506  (0.083998); expected 358.6 (0.02)
Passed bias filter:                      697  (0.0388756); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.64u 0.29s 00:00:00.93 Elapsed: 00:00:00.47
# Mc/sec: 3345.83
//
Query:       EEA20813.1  [L=540]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    5.1e-17   62.1   0.0    1.1e-16   61.0   0.0    1.6  1  DDE_1        DDE superfamily endonuclease
    6.6e-10   38.9   0.0    2.8e-09   36.8   0.0    2.2  1  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
     0.0077   16.0   0.0      0.022   14.5   0.0    1.7  1  HTH_psq      helix-turn-helix, Psq domain
  ------ inclusion threshold ------
       0.03   14.6   0.6        0.1   13.0   0.6    1.9  1  Tup_N        Tup N-terminal
      0.048   13.6   1.0      0.078   13.0   1.0    1.2  1  Sds3         Sds3-like
      0.077   13.2   0.9       0.14   12.3   0.9    1.4  1  PknG_rubred  Protein kinase G rubredoxin domain


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.0   0.0   3.6e-20   1.1e-16       4     107 ..     207     312 ..     204     355 .. 0.90

  Alignments for each domain:
  == domain 1  score: 61.0 bits;  conditional E-value: 3.6e-20
       DDE_1   4 ltvllcanaagsekLkplvigkak.sprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrle..aekrkilLlldssrshetvel.lesel 97 
                  +++++   +++  L++++i+kak + r  ++   ++ ++d+++++++++w+t++i+ eWL  +f++ ++    +r+ +L+ld+++sh t+e+ + + +
  EEA20813.1 207 CVTAIEVTNSTGWALPSYIIFKAKkNVRLGWF---DDLPSDWRINISENGWTTDQIGLEWLkTHFIPNINgrTMGRYRMLILDGHGSHLTAEFdHTCIE 302
                 56677778888999********9725677888...99*********************************999************************** PP

       DDE_1  98 qniklvflPa 107
                 +ni  +fl  
  EEA20813.1 303 NNIIPIFLKR 312
                 *******864 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.8   0.0   9.5e-13   2.8e-09       3      62 ..      71     126 ..      69     130 .. 0.89

  Alignments for each domain:
  == domain 1  score: 36.8 bits;  conditional E-value: 9.5e-13
                  HHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT.S- CS
  HTH_Tnp_Tc5   3 elEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh.gl 62 
                   +E++L++W+ +l++rg p++++l+re+ + l+      ++++ +++++W+++  kR  ++
   EEA20813.1  71 FEEESLIKWVLDLTKRGLPPRHSLVREMVNYLL-----SQHGNRQVGEKWVYNLVKRRpEI 126
                  589*****************************6.....4469***************8555 PP

>> HTH_psq  helix-turn-helix, Psq domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.0   7.5e-06     0.022      18      39 ..      33      54 ..      23      58 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 7.5e-06
     HTH_psq 18 SirkAArkYgiPrsTLwrrkrg 39
                Sir+AAr+Y iPr+ L+ r++g
  EEA20813.1 33 SIREAARIYTIPRTPLQDRLNG 54
                9****************88776 PP

>> Tup_N  Tup N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.6   3.3e-05       0.1      37      61 ..     439     463 ..     433     474 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 3.3e-05
       Tup_N  37 qiqElqqirqtlyeLeeahrkikqq 61 
                  i+El+ +r+++++L +ah+k kq+
  EEA20813.1 439 SINELTIVRKEVHDLRAAHEKEKQK 463
                 69*********************97 PP

>> Sds3  Sds3-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   1.0   2.6e-05     0.078     129     213 ..     387     483 ..     341     485 .. 0.72

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 2.6e-05
        Sds3 129 hta......glanesatstepvelltdrrslrtnsdsdflqelsd......leeLqallfggepg...kenkekkkrkastrestksapglqslkeeev 212
                 ++       + +n+ ++ +  + ++++r+s+rt+s s+  +   +        ++++l    ++         ++k+k++ + s+k+ ++ q+ + eev
  EEA20813.1 387 SNIqssclqTPQNPRQFNR-QMITIKERMSRRTRSPSEVIDGAISriskayGMSINELTIVRKEVhdlR--AAHEKEKQKRQRSKKQIATEQGITREEV 482
                 3333323333678877877.7999********9999988776555677787566666666666667542..4556667777889**************9 PP

        Sds3 213 n 213
                 +
  EEA20813.1 483 Q 483
                 6 PP

>> PknG_rubred  Protein kinase G rubredoxin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.9   4.7e-05      0.14      13      99 ..     433     525 ..     418     534 .. 0.67

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 4.7e-05
                  XXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXX..XXXXXXXXXXXXETTTTEEEE------TTGGG-CSS---GG......G-B-TTT- CS
  PknG_rubred  13 saatarpvstqavfRpevdddedsaslealsteastrs..asatrslspvrrlGgGLveiprvveadPleAlltnpvvpEs......kRfCwrCG 99 
                  s+a   ++++ +++R+ev d    + +e+++++ s+++  +++  ++++v+ l  G ve+ +vv++ P++   t+p +p s      +  C+ CG
   EEA20813.1 433 SKAYGMSINELTIVRKEVHDLRAAHEKEKQKRQRSKKQiaTEQGITREEVQALVQGQVEVSQVVTTTPAAP--TDPKLPASqpvarrQFRCSGCG 525
                  566667778899******7776655555555554444423444456999****************999764..4554444311110033466676 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (540 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1490  (0.0831056); expected 358.6 (0.02)
Passed bias filter:                      914  (0.0509789); expected 358.6 (0.02)
Passed Vit filter:                        95  (0.00529868); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.72u 0.30s 00:00:01.02 Elapsed: 00:00:00.48
# Mc/sec: 3380.45
//
Query:       EEA20814.1  [L=249]
Description: hypothetical protein PMAA_046330 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (249 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       438  (0.0244297); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.45
# Mc/sec: 1671.06
//
Query:       EEA20815.1  [L=1188]
Description: SET domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    6.2e-53  179.4   0.0      2e-52  177.8   0.0    2.0  1  N-SET      COMPASS (Complex proteins associated with Set1p) c
    4.9e-27   93.4   1.0      1e-26   92.3   0.4    1.9  2  SET_assoc  Histone lysine methyltransferase SET associated
    3.2e-21   76.4   0.3    1.9e-20   73.9   0.2    2.5  2  SET        SET domain
    0.00019   21.1   0.0    0.00042   20.1   0.0    1.6  1  RRM_1      RNA recognition motif. (a.k.a. RRM, RBD, or RNP do


Domain annotation for each model (and alignments):
>> N-SET  COMPASS (Complex proteins associated with Set1p) component N
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  177.8   0.0   4.4e-56     2e-52       3     173 .]     872    1040 ..     870    1040 .. 0.94

  Alignments for each domain:
  == domain 1  score: 177.8 bits;  conditional E-value: 4.4e-56
       N-SET    3 lldldglqelikDeeDlkflkkllkeldekeassdignlelwawkqkeikeln..glegikekeekiegyylenatGcarteGykkIpdkeKskYLp 97  
                  +ldldg+q+likD+eDl fl++++++++    +s++g++++wawkq+e k ln  g++g++ ++++i gy ++n+tG+arteG k+I ++eKskYLp
  EEA20815.1  872 VLDLDGWQTLIKDDEDLDFLRDIMSDTL----PSKVGDITIWAWKQREAKLLNrfGETGPVFTPTTIPGYFVPNSTGSARTEGKKRIFEAEKSKYLP 964 
                  79*************************9....*********************9999**************************************** PP

       N-SET   98 hrrkvqkaletveaeakkdekaaaaaaaeeaaekesskqeissSRenRannRRfvadieaqkaal...gtesdlLslNq 173 
                  hr+kvqka+e++ea a++d+++  + +a+   +k ++   +s+SR++R++nRR++adi+aqk++l   g+++d+L++Nq
  EEA20815.1  965 HRIKVQKAREEREALAQSDPQSVLVDSAKAGPTKPVN---NSTSRSTRVQNRRLAADINAQKQVLppqGGDGDALRFNQ 1040
                  *********************9999988633333333...47************************************9 PP

>> SET_assoc  Histone lysine methyltransferase SET associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.3   0.4   2.3e-30     1e-26       1      66 []     442     511 ..     442     511 .. 0.99
   2 ?   -2.9   0.0       1.3   5.7e+03       1      14 [.    1122    1135 ..    1122    1156 .. 0.72

  Alignments for each domain:
  == domain 1  score: 92.3 bits;  conditional E-value: 2.3e-30
   SET_assoc   1 FiskksvpvhkvtvedlkkrLkkyeweriledktGyYivFndsk....eAerCfraedgtklftyrmvme 66 
                 Fi++++vpv ++t+++l+krL++++w+ +++dktGyYi+F++s+    e+ rC++++++t+lfty m+me
  EEA20815.1 442 FIAHCYVPVLGSTLPHLQKRLRTFDWKAVRCDKTGYYIIFENSRrgeeETMRCYKMCHMTPLFTYIMNME 511
                 9********************************************************************7 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.3
   SET_assoc    1 Fiskksvpvhkvtv 14  
                  Fi+++++p+++  +
  EEA20815.1 1122 FINHSCTPNCTAKI 1135
                  99999999998765 PP

>> SET  SET domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       1.4   6.2e+03      52      78 ..     530     557 ..     436     602 .. 0.62
   2 !   73.9   0.2   4.2e-24   1.9e-20       2     168 ..    1058    1162 ..    1057    1163 .. 0.93

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 1.4
                 X.HHHHHHHTTSSHHHHHHHHHHHHHHH CS
                 x.xxxxxxxxxxxxxxxxxxxxxxxxxx RF
         SET  52 t.kelakasastllqklakdqkqaeked 78 
                 + + +a a+ ++ l++++ +++++++++
  EEA20815.1 530 QaELKARAEEKRVLREAELEIEEEKQQR 557
                 2233333333334444444444443333 PP

  == domain 2  score: 73.9 bits;  conditional E-value: 4.2e-24
                  CEEEESSXBXTTXEEEEEE.ECCEECHHHHHHHHHH........HTEEEEEXGGXXGGSXHHHHHHHTTSSHHHHHHHHHHHHHHHHHHTHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         SET    2 rGvfAtedIpkgeficeyp.eeiiltkdeadksele........aylfslpeapknlaftkelakasastllqklakdqkqaekedtdaalkasska 89  
                  +G++A e+I ++++i+ey+ e   ++++ ad +e           ylf ++                                              
  EEA20815.1 1058 WGLYAEENITANDMIIEYVgE--KVRQQVADMRERRylksgigsSYLFRID---------------------------------------------- 1106
                  *******************77..8999999999888889999999999999.............................................. PP

                  XTTTSXXXHCCCCCHCCCHEEEETEEEEEECCCGTTGGGCEEXSSSSEEEEEEEETTSSEEEEEESSXBXTTEEEEEXT CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         SET   90 esdlnaskpeagafsaiagysidaralksgngagplarflNHsCdpNcnltvqnvlrgprvavfAtrdIkkGeEltidY 168 
                                    + +id  a+k g+ a    rf+NHsC+pNc++ + +v++++r++++A+rdI+k+eElt+dY
  EEA20815.1 1107 -----------------ENAVID--ATKRGGIA----RFINHSCTPNCTAKIIRVDGSKRIVIYALRDISKDEELTYDY 1162
                  .................6778**..77******....****************************************** PP

>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   0.0   9.4e-08   0.00042       2      52 ..     265     316 ..     264     318 .. 0.85

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 9.4e-08
                 EEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHH CS
       RRM_1   2 fVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedA 52 
                 +V+++ p +    + +lFs fG++ +i+  +d  tg++ g++ V+F++  + 
  EEA20815.1 265 VVTGFDPLTPIAPITALFSSFGEVAHIDNRTDpVTGRPLGICLVKFKDATSF 316
                 5666666666667889*******************************98776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1188 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       638  (0.0355848); expected 358.6 (0.02)
Passed bias filter:                      382  (0.0213063); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.84u 0.31s 00:00:01.14 Elapsed: 00:00:00.50
# Mc/sec: 7200.29
//
Query:       EEA20816.1  [L=584]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.9e-17   61.9   0.1    2.6e-16   59.2   0.1    2.4  3  Rad60-SLD  Ubiquitin-2 like Rad60 SUMO-like
      1e-10   42.0   0.0    1.4e-09   38.4   0.0    2.8  2  Trm112p    Trm112p-like protein
    0.00022   20.9   0.0    0.00061   19.5   0.0    1.8  1  ubiquitin  Ubiquitin family


Domain annotation for each model (and alignments):
>> Rad60-SLD  Ubiquitin-2 like Rad60 SUMO-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0      0.45   2.7e+03      29      62 ..     233     268 ..     223     269 .. 0.77
   2 !   59.2   0.1   4.3e-20   2.6e-16       2      70 ..     324     392 ..     323     393 .. 0.97
   3 ?   -3.2   0.0       1.3     8e+03      40      54 ..     398     412 ..     394     413 .. 0.71

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.45
                 HHHHHHT----..TT-EEEETTEE--TTSBGGGSS- CS
   Rad60-SLD  29 ayrkkkgipee..qkvrLiFDGeeLdpnstvedldi 62 
                   + ++g +++  ++v+L+ + ++L +  t+++ld+
  EEA20816.1 233 TWCARQGFDQKmtDSVYLTWNRRRLFDVTTCKSLDV 268
                 5666777777666999***99999999999999885 PP

  == domain 2  score: 59.2 bits;  conditional E-value: 4.3e-20
                 EEEEEESSS--EEEEEETTSBHHHHHHHHHHHHT----TT-EEEETTEE--TTSBGGGSS--TTEEEEE CS
   Rad60-SLD   2 kiilkgkdgkevkikVkptttvskLieayrkkkgipeeqkvrLiFDGeeLdpnstvedldiedgdtidv 70 
                  i+lk++++ ++k+kV p t+v +++  +++k++i+ + k+ L FDG+ Ldp+s+++d+di+d+d++++
  EEA20816.1 324 HIVLKSPSHGDLKVKVLPRTPVLQIMANFKSKRNISSDLKILLSFDGDILDPDSQLKDYDIDDMDLVEA 392
                 69****************************************************************996 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 1.3
                 TT-EEEETTEE--TT CS
   Rad60-SLD  40 qkvrLiFDGeeLdpn 54 
                  +  L F++ eL+++
  EEA20816.1 398 ASTPLHFKDAELEQQ 412
                 566688999999876 PP

>> Trm112p  Trm112p-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.4   0.0   2.3e-13   1.4e-09      17      68 .]     387     491 ..     296     491 .. 0.77
   2 ?   -0.2   0.0      0.26   1.5e+03      52      63 ..     511     522 ..     501     523 .. 0.90

  Alignments for each domain:
  == domain 1  score: 38.4 bits;  conditional E-value: 2.3e-13
                 -.........................................-HHHHHHHHH.TT---S-SS----S...........CHHTTEECCCCEEEETTTTEE CS
     Trm112p  17 L.........................................dwealvevaa.lglnelpkekpedy...........ellleldieegeLvCpncgra 62 
                                                           dw++l  +a+ lg++++   kp d            +ll+e++++eg+L C ncg+ 
  EEA20816.1 387 MdlveacrispastplhfkdaeleqqeldfnpslirnilpriDWDSLRITAQeLGFPDISNIKPNDDqidenmlrdlhKLLMETHVIEGKLCCANCGHE 485
                 055555555555555588888888888899999999999999****************9999999999******************************* PP

                 EEEETT CS
     Trm112p  63 YpIkdG 68 
                 Y Ik+G
  EEA20816.1 486 YQIKEG 491
                 ****98 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.26
                 CEEEETTTTEEE CS
     Trm112p  52 geLvCpncgraY 63 
                 ++L C++ gr+Y
  EEA20816.1 511 EVLHCTELGRHY 522
                 689********9 PP

>> ubiquitin  Ubiquitin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0     1e-07   0.00061       2      65 ..     326     390 ..     325     394 .. 0.89

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 1e-07
                 EEEETTSEEEEEEEETTSBHHHHHHHHHHHHTSSGGGE.EEEETTEEE-TTSBHGGHTTSTTEEE CS
   ubiquitin   2 tvktldgkkitleveesdtveelKekiaekegipaeqq.rLiysGkvLedertleeygiqdgstl 65 
                  +k+ ++ ++ ++v + + v+++++   +k +i  +    L ++G +L+ ++ l++y+i+d + +
  EEA20816.1 326 VLKSPSHGDLKVKVLPRTPVLQIMANFKSKRNISSDLKiLLSFDGDILDPDSQLKDYDIDDMDLV 390
                 56777788899*********************9999776999*****************998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (584 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       675  (0.0376485); expected 358.6 (0.02)
Passed bias filter:                      399  (0.0222544); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.63u 0.23s 00:00:00.86 Elapsed: 00:00:00.43
# Mc/sec: 4040.88
//
Query:       EEA20817.1  [L=80]
Description: U6 snRNA-associated Sm-like protein LSm6, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.5e-20   70.4   0.0    8.4e-20   70.2   0.0    1.0  1  LSM       LSM domain
     0.0019   18.3   0.0     0.0021   18.1   0.0    1.1  1  SM-ATX    Ataxin 2 SM domain
  ------ inclusion threshold ------
      0.014   15.5   0.1      0.016   15.3   0.1    1.1  1  LSM14     Scd6-like Sm domain
      0.056   13.1   0.0      0.075   12.7   0.0    1.2  1  Hfq       Hfq protein


Domain annotation for each model (and alignments):
>> LSM  LSM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.2   0.0   1.9e-23   8.4e-20       2      66 ..      15      78 ..      14      79 .. 0.97

  Alignments for each domain:
  == domain 1  score: 70.2 bits;  conditional E-value: 1.9e-23
                HHHHTTTSEEEEEETTSEEEEEEEEEEETTSEEEEEEEEEEETTETEEEEEEEEEEEGGGEEEEE CS
         LSM  2 flkklinkkvtvelkngrelrGtLkgfDqfmNlvLedveetlkdkkekrklglvliRGnnivlis 66
                fl++ ++  vtv+l++g ++ G L+++D +mN+ Le++ee+++++   r++g+ ++RGnn+++is
  EEA20817.1 15 FLSEITGAPVTVKLNSGVVYQGELQSVDGYMNIALEKTEEYVNGQ-LRRSYGDAFVRGNNVLYIS 78
                899*****************************************9.******************8 PP

>> SM-ATX  Ataxin 2 SM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   4.8e-07    0.0021       8      49 ..      16      55 ..      12      74 .. 0.87

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 4.8e-07
                HHTTTTSEEEEEETTS-EEEEEEEEE-T..T--EEEEEEEET CS
      SM-ATX  8 ltslvGkevevtvknGevyeGifstvslekdfsvvLkmarkv 49
                l  + G +v+v++ +G vy+G +++v+    ++++L+ + + 
  EEA20817.1 16 LSEITGAPVTVKLNSGVVYQGELQSVDG--YMNIALEKTEEY 55
                67789**********************9..999999998776 PP

>> LSM14  Scd6-like Sm domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.3   0.1   3.6e-06     0.016       2      39 ..      19      55 ..      18      77 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 3.6e-06
       LSM14  2 fIGskislisksdirYeGilceinledstiaLqnvrsf 39
                + G+ + ++ +s+++Y+G l +++    +iaL++   +
  EEA20817.1 19 ITGAPVTVKLNSGVVYQGELQSVD-GYMNIALEKTEEY 55
                568999******************.7889999994433 PP

>> Hfq  Hfq protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   1.7e-05     0.075      14      43 ..      22      52 ..      14      59 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 1.7e-05
                -EEEEEETTS-EEEEEEEEE-SSE.EEEEET CS
         Hfq 14 ipvtifLvnGiklkGviksfDnft.vlLesd 43
                 pvt+ L +G+  +G ++s D ++ + Le++
  EEA20817.1 22 APVTVKLNSGVVYQGELQSVDGYMnIALEKT 52
                79*********************85666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (80 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       399  (0.0222544); expected 358.6 (0.02)
Passed bias filter:                      353  (0.0196888); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.35u 0.25s 00:00:00.60 Elapsed: 00:00:00.40
# Mc/sec: 601.03
//
Query:       EEA20818.1  [L=384]
Description: translation initiation factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.2e-73  244.9   1.2    1.1e-72  244.7   1.2    1.0  1  IF-2B     Initiation factor 2 subunit family


Domain annotation for each model (and alignments):
>> IF-2B  Initiation factor 2 subunit family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  244.7   1.2     6e-77   1.1e-72       2     281 ..      45     365 ..      44     366 .. 0.93

  Alignments for each domain:
  == domain 1  score: 244.7 bits;  conditional E-value: 6e-77
                 S-SHHHHHHHHHHHHHHHHHHCC.....CSTHHHHHHHHHHHHHHHHTSSTS-HHHHHHHHHHHH...HHHCCTTTSSHHHHHHHHHHHHHHHHHHHHH CS
       IF-2B   2 vrGspaiaiaalevllevikdak.....tskvaeLkeelrkaidlLkkarPtavslgnairrllk...eiselksssdvkeakksliekikelikeiee 92 
                 vrG+paiai+a+ +l+ ++++++      s ++e    + +++ +L  +rPtav+l  a r + +   e    ++ s+ ++  ++++++++ ++ +++ 
  EEA20818.1  45 VRGAPAIAIVAILSLAVELSEIQtagklSSSSEEVGLFIIEKLHYLVTSRPTAVNLADAARKFETmvtE-HTKTQGSTGQSLVAAYLQEAELMLVHDLS 142
                 8*********************954444455666688899***********************994322.2345566777788889************* PP

                 HHHHHHHHHHTTC........-TTEEEEEES--SH........HHHHHHHHHHTTEEEEEEEEEXTTTTHH.HTHHHHHHHTTXEEEEEEGGGHHHHHH CS
       IF-2B  93 adekigdiaaeli........kdgdtilTicnskt........vlevlraaakekkkfkVivvEsrPrlqG.rltakeLvqagipvtlitdsavayvms 174
                  +++ig+++a+ i        + + ++lT+cn+++        +l+v+r++++ +   +V+++E+rP++qG rlta+eLv+++ p tlitds++a ++ 
  EEA20818.1 143 DNKNIGAYGAKWIleraategQAKVNVLTHCNTGSlatagygtALGVIRSLHEGNALNRVYCTETRPYNQGaRLTAYELVHEKMPATLITDSMAASLLA 241
                 ******************9999999************************************************************************** PP

                 C...TESEEEEEXSEEETTSEEEEETTHHHHHHHHHHTTXEEEEEXXGGGBESTSSSGGGSSXXBEXTHHHHEETTEESSTT..............TEE CS
       IF-2B 175 e...evdkvivGAdrilenGaiankiGTsslAvlAkefnipvlvvaeslkfservqldedifieerdpeellnitgeriaee..............elk 256
                 +   +v++++vGAdr+++nG++ankiGT+ lAvlAk + +++lv+a+ +++++ ++ +++i+ieer+p e++ i+g+                    ++
  EEA20818.1 242 KpesKVSAIVVGADRVAANGDTANKIGTYALAVLAKYHGVKFLVAAPRTTIDRGTPSGNEIVIEERAPSEVTTIKGPLQGRVgdalqmetiqlaatGID 340
                 99999***********************************************************************997555999************** PP

                 EEEBSEEEEEGGGXSEEEETTEEEX CS
       IF-2B 257 vvnpafDvtPpelItliITevGvlp 281
                 v+npafDvtP+ lI+++ITe+Gv++
  EEA20818.1 341 VWNPAFDVTPAALIDAVITEKGVVE 365
                 **********************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (384 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       380  (0.0211947); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2558.33
//
Query:       EEA20819.1  [L=694]
Description: glucosamine-fructose-6-phosphate aminotransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-60  202.7   0.1      3e-32  111.2   0.1    2.3  2  SIS       SIS domain
    8.6e-17   61.6   0.0    1.7e-16   60.7   0.0    1.4  1  GATase_6  Glutamine amidotransferase domain
    1.8e-10   40.8   0.0    4.3e-10   39.6   0.0    1.6  1  GATase_7  Glutamine amidotransferase domain
     0.0032   16.4   0.0     0.0051   15.8   0.0    1.3  1  GATase_4  Glutamine amidotransferases class-II


Domain annotation for each model (and alignments):
>> SIS  SIS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.2   0.1   6.8e-36     3e-32       2     130 ..     375     502 ..     374     503 .. 0.98
   2 !   89.4   0.0   3.8e-29   1.7e-25       3     129 ..     548     675 ..     546     676 .. 0.95

  Alignments for each domain:
  == domain 1  score: 111.2 bits;  conditional E-value: 6.8e-36
                 HCTSSEEEEEESHHHHHHHHHHHHHHHHHHTSEEEEEEHHHHHHTGGGG-STTCEEEEEESSSHHHHHHHHHHHHHHTTSEEEEEESSTTSHHHHHSSE CS
         SIS   2 LakakriyvlGaGtsyaiakelalkleeiggivvevedaselkhgvlalideddlvilisfsgetkdlvaaaelakergakiiaITdskgsplareadl 100
                 ++ ++ri+++++Gtsy++++ ++  +ee+++i+ +ve+as++ ++  a++ +dd ++++s+sget+d+++a++++ erga +++I +  gs+++  +++
  EEA20819.1 375 IRRCRRIIFIACGTSYHSCMAVRGVFEELTEIPIAVELASDFLDR-QAPVFRDDTCVFVSQSGETADSLMALRYCLERGALTVGIVNVVGSSISLLTHC 472
                 789******************************************.9**************************************************** PP

                 EEEEEEECHCSSSHCHHHHHHHHHHHHHHH CS
         SIS 101 alyinaepetlvastksltaqlaaldalav 130
                  ++ina+pe++vastk++t+q++a  ++a+
  EEA20819.1 473 GVHINAGPEIGVASTKAYTSQFVAMVMFAL 502
                 ************************999986 PP

  == domain 2  score: 89.4 bits;  conditional E-value: 3.8e-29
                 CTSSEEEEEESHHHHHHHHHHHHHHHHHHTSEEEEEEHHHHHHTGGGG-STTCEEEEEESSSHHHHHHHHHH.HHHHTTSEEEEEESSTTSHHHHHSSE CS
         SIS   3 akakriyvlGaGtsyaiakelalkleeiggivvevedaselkhgvlalideddlvilisfsgetkdlvaaae.lakergakiiaITdskgsplareadl 100
                  ++k++++lG+G++y++a+e+alk++ei++ ++e++ ++elkhgvlal+de+ ++i+i ++++ + + ++a  ++ +rg+++i+I+++++    ++ ++
  EEA20819.1 548 KNQKSLLLLGRGSQYSTALEGALKIKEISYLHCEAVMSGELKHGVLALVDENLPIIMILTRDNIFAKSLNAYqQVIARGGRPIVICNENDEEFPTSQTE 646
                 6899*******************************************************99998887777777************************** PP

                 EEEEEEECHCSSSHCHHHHHHHHHHHHHH CS
         SIS 101 alyinaepetlvastksltaqlaaldala 129
                 +++i++    l+++++++++ql+a+++++
  EEA20819.1 647 KIEIPKTVDCLQGLLNVIPLQLIAYWLAV 675
                 *****99999****************986 PP

>> GATase_6  Glutamine amidotransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.7   0.0   3.7e-20   1.7e-16       8     123 ..      75     200 ..      68     209 .. 0.81

  Alignments for each domain:
  == domain 1  score: 60.7 bits;  conditional E-value: 3.7e-20
    GATase_6   8 slvedevalaHvRlaivglaeeegaqPf.psedgrlllvhNGeiynykelreelpalkglafrsrsDtevllall....eelG........eevlerlr 93 
                 + +++++++aH+R+a++g + +  ++P  + ++ ++++vhNG i nykel++ l++ kg +f++++Dte +++l+    ++++        ++v+++l+
  EEA20819.1  75 KTYDSHAGIAHTRWATHGPPSRINCHPHrSDPKWEFSVVHNGIITNYKELKALLES-KGFRFETETDTECIAKLAkylyDQHPdidftvlaKAVIKELQ 172
                 567899**************88888***8888999*********************.****************9978884444566667747777**** PP

    GATase_6  94 Gmfafaiwdk.rentlilardrlgvkplyya 123
                 G+f   + +   ++++i a  r g +pl+++
  EEA20819.1 173 GAFGLLMKSVhYPHEVIAA--RKG-SPLVIG 200
                 *998877776666666666..445.666655 PP

>> GATase_7  Glutamine amidotransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.6   0.0   9.7e-14   4.3e-10      20      94 ..     106     192 ..      95     208 .. 0.83

  Alignments for each domain:
  == domain 1  score: 39.6 bits;  conditional E-value: 9.7e-14
    GATase_7  20 edgrlvivfnGeiyNykelreeLeakghrfrtksDtevllallea...........ewgeealerlnGmfAfaiwd.eeekrlllaR 94 
                  + ++ +v+nG i+Nykel++ Le+kg+rf+t++Dte +++l ++              ++++++l+G f +++   +  +++++aR
  EEA20819.1 106 PKWEFSVVHNGIITNYKELKALLESKGFRFETETDTECIAKLAKYlydqhpdidftVLAKAVIKELQGAFGLLMKSvHYPHEVIAAR 192
                 556799***********************************99989999****9977788899*******99876623333566666 PP

>> GATase_4  Glutamine amidotransferases class-II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   1.1e-06    0.0051      70     133 ..      78     144 ..      39     213 .. 0.85

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 1.1e-06
    GATase_4  70 ksknvvaHiRkatqGevklenthpFvRelwgrewifAHnGdlkeykpkl....egrfePvGsTDsEla 133
                  s+  +aH R at+G  +  n+hp  R+  + e+   HnG +++yk+      ++ f+   +TD+E +
  EEA20819.1  78 DSHAGIAHTRWATHGPPSRINCHPH-RSDPKWEFSVVHNGIITNYKELKalleSKGFRFETETDTECI 144
                 58899*******************6.77777888889*****99988665677778888889999975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (694 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       519  (0.0289475); expected 358.6 (0.02)
Passed bias filter:                      467  (0.0260472); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.68u 0.30s 00:00:00.98 Elapsed: 00:00:00.48
# Mc/sec: 4379.58
//
Query:       EEA20820.1  [L=214]
Description: DMRL synthase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.7e-55  186.1   1.3    4.8e-55  185.3   1.3    1.4  1  DMRL_synthase  6,7-dimethyl-8-ribityllumazine synthase
  ------ inclusion threshold ------
      0.088   12.9   0.0       0.12   12.5   0.0    1.2  1  GalBD_like     Galactose-binding domain-like


Domain annotation for each model (and alignments):
>> DMRL_synthase  6,7-dimethyl-8-ribityllumazine synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  185.3   1.3   5.3e-59   4.8e-55       1     138 [.      17     202 ..      17     205 .. 0.95

  Alignments for each domain:
  == domain 1  score: 185.3 bits;  conditional E-value: 5.3e-59
                    TEEEEEEEESTTHHHHHHHHHHHHHHHHHCTTSSCCEEEEEESSCCCHHHHHHHHCTS...................................... CS
  DMRL_synthase   1 glriaiVvarfneeitdkllegaldelkeagvaeenidvvtVPGafElplaakklaes...................................... 58 
                    glriaiV+ar+n++i+d+l++ga+++l + gv+++ni+++tVPG++Elp+a+++++++                                      
     EEA20820.1  17 GLRIAIVHARWNTKIIDALVSGAVNSLISTGVSKDNIVIQTVPGSYELPIAVQNIYRAshvqaaassttgniaatdllssstsdltqqatttttss 112
                    68*******************************************************7789999******************************** PP

                    ......TT-..SEEEEEEEEE--SSCHHHHHHHHHHHHHHHHHHHCTS-EEEEEEEESSHHCCHHCCT.STC...CCHHHHHHHHHHHHHH CS
  DMRL_synthase  59 ......sky.ldavialGvvirGetphfeyvaeavskglmrvsldtgvPvifgvltvdteeqalerag.gka...gnkGeeaaeaaleman 138
                          s   +da+ia+Gv+i+Get+hfey++eavs+g+mrv+l+ +vPvifg+lt  teeq lerag g +   +n+Ge+++ aa+e+a 
     EEA20820.1 113 lsasaaSTApFDAIIAIGVLIKGETMHFEYISEAVSHGIMRVQLEANVPVIFGLLTLLTEEQGLERAGlG-SgkkHNHGEDWGLAAVELAL 202
                    *****844669********************************************************853.3466*************985 PP

>> GalBD_like  Galactose-binding domain-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   1.4e-05      0.12      63     125 ..      25      89 ..      19     129 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.4e-05
  GalBD_like  63 rGwdvkkiddvldGkWslkinGlvernklvyqtiPqnfrfep..gktykvsfdyeaGsdgtyavv 125
                 + w++k id ++ G     i   v+++++v qt+P  + +     + y+ s    a s  t +++
  EEA20820.1  25 ARWNTKIIDALVSGAVNSLISTGVSKDNIVIQTVPGSYELPIavQNIYRASHVQAAASSTTGNIA 89 
                 67************99888888899**********999875411456777776666655554444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (214 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       588  (0.032796); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.42
# Mc/sec: 1513.99
//
Query:       EEA20821.1  [L=292]
Description: proteasome subunit alpha type 3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.4e-45  153.9   0.1      3e-32  111.7   0.0    2.3  2  Proteasome      Proteasome subunit
    5.3e-12   45.2   1.0    6.2e-12   45.0   0.0    1.7  2  Proteasome_A_N  Proteasome subunit A N-terminal signature


Domain annotation for each model (and alignments):
>> Proteasome  Proteasome subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.7   0.0   3.3e-36     3e-32       1     117 [.      31     145 ..      31     168 .. 0.94
   2 !   40.2   0.0   2.6e-14   2.4e-10     115     182 ..     169     235 ..     164     243 .. 0.90

  Alignments for each domain:
  == domain 1  score: 111.7 bits;  conditional E-value: 3.3e-36
                 HHHS-EEEEEEETTEEEEEEEEEEEETTEEEESSSSTSEEEEETTEEEEEEESHHHHHHHHHHHHHHHHHHHHHHSSGTCHHHHHHHHHHHHHHHHHHC CS
  Proteasome   1 vkkGttvvGikgkdgvvlaadkratagskllskstveKifkiddhigvafaGlaaDartlvrraraeaqlyrlrygrpipverlvarvaaklqaytqrs 99 
                 v++G+t++Gi++kdgvvla++k +t  skll++   ++i  +d+++g++ +Gl++D+r +v+rar ea+++r +y+ pip++ l++r+  ++qayt++s
  EEA20821.1  31 VENGGTAIGIRCKDGVVLAVEKLIT--SKLLKPGANKRIATVDRNVGIVSSGLVPDGRHFVSRARDEAASWRKTYKGPIPTSALANRLGGYVQAYTLYS 127
                 689**********************..************************************************************************ PP

                 TTTTTSEEEEEEEEETTT CS
  Proteasome 100 grrpfgvslliagvdeeg 117
                 ++rpfgv  +++g+d e 
  EEA20821.1 128 SVRPFGVTSIVGGWDSEA 145
                 ***************775 PP

  == domain 2  score: 40.2 bits;  conditional E-value: 2.6e-14
                 TTTEEEEEEEETTSEEEEESSEEEESTTHHHHHHHHHHHH..STTBSHHHHHHHHHHHHHHHHHHBTTSC CS
  Proteasome 115 eeggpeLyqidpsGsyieekdavaiGsgseaaktalekey..kedltleeavelavkalkealerdklsg 182
                 + ggp Ly+i+psG y+++ + +a+G+g++aak+ lek+     +l+l ++v+ a ++++ a+e+dk   
  EEA20821.1 169 KAGGPGLYMIEPSGLYWGY-YGAATGKGRQAAKAELEKLDlpAGNLSLLDGVKEAARIIYVAHEEDK--D 235
                 5799***************.8*******************9999********************884..4 PP

>> Proteasome_A_N  Proteasome subunit A N-terminal signature
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.0   0.0     7e-16   6.2e-12       1      23 []       8      30 ..       8      30 .. 0.99
   2 ?   -3.3   0.3      0.88   7.9e+03      10      13 ..      83      86 ..      83      86 .. 0.95

  Alignments for each domain:
  == domain 1  score: 45.0 bits;  conditional E-value: 7e-16
  Proteasome_A_N  1 YDrslttFSPdGRLfQVEYAmkA 23
                    YD+s ++FSPdGR fQVEYA kA
      EEA20821.1  8 YDLSNSVFSPDGRNFQVEYAVKA 30
                    **********************9 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 0.88
  Proteasome_A_N 10 PdGR 13
                    PdGR
      EEA20821.1 83 PDGR 86
                    9**9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (292 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       525  (0.0292822); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2048.46
//
Query:       EEA20822.1  [L=240]
Description: hypothetical protein PMAA_046410 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.9e-06   26.0   1.3    1.2e-05   25.2   1.3    1.4  1  Zn_Tnp_IS91      Transposase zinc-binding domain
     0.0085   16.4   1.0      0.018   15.4   1.0    1.5  1  Lar_restr_allev  Restriction alleviation protein Lar
  ------ inclusion threshold ------
      0.082   12.5   0.0       0.27   10.8   0.0    1.8  2  GNAT_acetyltran  GNAT acetyltransferase
       0.35   10.7   3.2        4.5    7.1   1.2    2.5  2  zinc_ribbon_2    zinc-ribbon domain


Domain annotation for each model (and alignments):
>> Zn_Tnp_IS91  Transposase zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   1.3   2.7e-09   1.2e-05      40      81 ..       3      48 ..       1      56 [. 0.81

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 2.7e-09
  Zn_Tnp_IS91 40 yeCeeCg...hekivyfsCksrh.CpsCqkkateewlekqqeellp 81
                 + C+ Cg   h++ +y++C++   C++C+  +++ wl++q++el+ 
   EEA20822.1  3 FNCPYCGhaaHSTAMYMTCEESTlCQQCGLSESDAWLRNQEDELVA 48
                 5677776444889******99888******************9986 PP

>> Lar_restr_allev  Restriction alleviation protein Lar
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   1.0     4e-06     0.018       5      47 ..       4      45 ..       3      54 .. 0.85

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 4e-06
  Lar_restr_allev  5 pCPfCggravlersqrvvaeigqcvyCadCga..stpwfkiaede 47
                      CP Cg++a    ++ + +e      C++Cg   s  w ++ ede
       EEA20822.1  4 NCPYCGHAAHSTAMYMTCEE---STLCQQCGLseSDAWLRNQEDE 45
                     5******************9...*********7777777777666 PP

>> GNAT_acetyltran  GNAT acetyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0     6e-05      0.27     164     207 ..      42      85 ..      39      92 .. 0.93
   2 ?   -2.4   0.0      0.62   2.8e+03     187     199 ..     182     194 ..     163     197 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 6e-05
  GNAT_acetyltran 164 kngeivsgasSysvyekgieieidTkedyrrkgLAtivaaalil 207
                      +++e+v+  s+ys+  +   ++++ k++  r  +A+++a+++i 
       EEA20822.1  42 QEDELVARLSAYSITPQVEHVSVESKPAANRIVYASAAAHSFIV 85 
                      679***************************************96 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.62
  GNAT_acetyltran 187 dTkedyrrkgLAt 199
                      +T ++ +++gLA+
       EEA20822.1 182 NTVNQSQNQGLAQ 194
                      6778889999998 PP

>> zinc_ribbon_2  zinc-ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   1.2     0.001       4.5      16      21 ..       5      10 ..       2      11 .. 0.83
   2 ?    2.8   0.0     0.023     1e+02      12      20 ..      23      31 ..      22      32 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.001
  zinc_ribbon_2 16 CpyCGt 21
                   CpyCG+
     EEA20822.1  5 CPYCGH 10
                   *****8 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.023
  zinc_ribbon_2 12 nakFCpyCG 20
                   +++ C +CG
     EEA20822.1 23 ESTLCQQCG 31
                   578899998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (240 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       656  (0.0365888); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.42
# Mc/sec: 1710.98
//
Query:       EEA20823.1  [L=384]
Description: NAD(+)-isocitrate dehydrogenase subunit I [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-83  280.5   0.0    2.4e-83  280.2   0.0    1.0  1  Iso_dh    Isocitrate/isopropylmalate dehydrogenase


Domain annotation for each model (and alignments):
>> Iso_dh  Isocitrate/isopropylmalate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  280.2   0.0   1.4e-87   2.4e-83       1     348 []      49     376 ..      49     379 .. 0.93

  Alignments for each domain:
  == domain 1  score: 280.2 bits;  conditional E-value: 1.4e-87
                 EEEEEEESTTHHHHHHHHHHHHHHHHHHHT-EEEEEE---TH.HHHHHHSSSS-HHHHHHHHHSSEEEEEE---CS.SSSSSHHHHHHHHHHHTTEEEE CS
      Iso_dh   1 kiallegdgiGpevveaalkvlkaakekaglelefeevdvGg.aaidetgeplpeetleaikeadvvllgavgtpk.ekevrpengLlaLrkeldlfan 97 
                 +++l++gdgiG ev e+++ ++ka +      +e+e+vdv+g  + +++ e l  e+++++++++  l+g + tp+ ++++++ n  +aLr+eld++a 
  EEA20823.1  49 TVTLIPGDGIGAEVAESVKTIFKADN--V--PIEWEQVDVSGvDTGNKHSEELFRESIASLRRNKLGLKGILHTPVeRSGHQSFN--VALRQELDIYAS 141
                 589********************988..5..59******97615678999**************************8899*****..***********9 PP

                 EEEEE-BCCTTCCSSBTHHHHCT-EEEEEEE-SSCGGCSSEEEEETTG.GGGEEEEEEEEEHHHHHHHHHHHHHHHHHTTTSEEEEEESTTTTHHHH.H CS
      Iso_dh  98 lrpvkvfeklkvksplkrevveevdlvivReltggiYfgeekekkgsifteevavdtklyseeeieriaraafelAlkrgkkkvtlvdKanvlksse.l 195
                 +  +k ++  ++k+       e+vdl+i+Re+t+g Y+g e++  +      v+ ++k ++++ +eria++a+  Al++++kk+t+++Kan++k ++ l
  EEA20823.1 142 VVLIKNIP--GYKT-----RHENVDLCIIRENTEGEYSGLEHQSVQG-----VVESLKIITRAKSERIAKFACSFALANNRKKITCIHKANIMKLADgL 228
                 98888873..3333.....3468********************9997.....899******************************************** PP

                 HHHHHHHHHCCTTTTSEEEEEEHHHHHHHHHHSGGGGSEEEE-HHHHHHHHHHHHHHTTSGCC-EEEEEETSS-EEEEE.SS---CCCTTSS-S-THHH CS
      Iso_dh 196 wrkiveevaeeeypdielehqlvDsaamqlvkspkqfdVivtkNlfGDilSDeaaalvGslGllpSaslgekkvaifEa.vHGsapdiagkdkaNpiav 293
                 +r+++++vae  yp +e ++++vD+a mq+v +p+qfdV+v++Nl+G ilS   aalvG+ G++p+ ++g ++va+fE+ +     di gkd+aNp+a 
  EEA20823.1 229 FRNTFKKVAE-SYPTLETNDMIVDNASMQAVSRPQQFDVMVMPNLYGGILSNIGAALVGGPGIVPGCNMG-REVAVFEPgCRHVGLDIKGKDQANPTAL 325
                 **********.***********************************************************.79*****95455667************* PP

                 HHHHHHHHHHTTT-HHHHHHHHHHHHHHHHH.TSCCHHHCTTSTCCCHHHHHHHHH CS
      Iso_dh 294 ilSaalmLryslgleeaAdkiekAvekvlea.givTkDlageaakevstsefgdav 348
                 ilS +++Lr+ lgl+e+A++i kAv +v+ + +i+T+D++g a    +t+ef+ av
  EEA20823.1 326 ILSGSMLLRH-LGLDEHANRISKAVYDVIGEgKIRTRDMGGVA----TTHEFTRAV 376
                 **********.******************99899********9....888888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (384 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       406  (0.0226449); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.24s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 2645.08
//
Query:       EEA20824.1  [L=281]
Description: methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.4e-14   52.7   3.5    9.1e-14   52.0   3.5    1.3  1  WBS_methylT      Methyltransferase involved in Williams-Beure
    4.6e-10   40.0   0.0    8.8e-10   39.1   0.0    1.5  1  Methyltransf_11  Methyltransferase domain
    1.5e-09   38.5   0.0    4.2e-09   37.0   0.0    1.9  1  Methyltransf_25  Methyltransferase domain
    0.00043   20.1   0.0    0.00067   19.5   0.0    1.4  1  Methyltransf_31  Methyltransferase domain
     0.0025   17.6   0.0     0.0047   16.7   0.0    1.4  1  PCMT             Protein-L-isoaspartate(D-aspartate) O-methyl
     0.0031   18.2   0.0     0.0082   16.9   0.0    1.8  1  Methyltransf_12  Methyltransferase domain
  ------ inclusion threshold ------
      0.039   13.3   0.0       0.26   10.6   0.0    2.1  2  Ubie_methyltran  ubiE/COQ5 methyltransferase family
       0.16   11.8   0.0       0.25   11.1   0.0    1.3  1  Methyltransf_23  Methyltransferase domain
        0.2   10.9   0.0        1.4    8.1   0.0    1.9  2  CMAS             Mycolic acid cyclopropane synthetase


Domain annotation for each model (and alignments):
>> WBS_methylT  Methyltransferase involved in Williams-Beuren syndrome
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.0   3.5   4.6e-17   9.1e-14      29      81 ..     224     278 ..     208     279 .. 0.74

  Alignments for each domain:
  == domain 1  score: 52.0 bits;  conditional E-value: 4.6e-17
  WBS_methylT  29 vkyekrrrkrkkr..kkkkkkavksreWilkKKerrrkkGkeVkrdSKYTGRkRk 81 
                  v++ + r+++++    ++ ++++ s+ Wil+KKe++ +kGk Vk+ SKYTGRkR+
   EEA20824.1 224 VDIVDSRKRDNAAkiARSLQEKKGSKSWILRKKEQMARKGKVVKASSKYTGRKRR 278
                  555444444333324444444555******************************7 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.1   0.0   4.4e-13   8.8e-10       1      96 []      52     161 ..      52     161 .. 0.89

  Alignments for each domain:
  == domain 1  score: 39.1 bits;  conditional E-value: 4.4e-13
                      EEET-TTSHHHHHHH....HTT..SEEEEEES-HHHHHHHHHHCCHHT-EEEETTEECCC.TSS-TT-EEEEEEES-CCC-..C.........C CS
  Methyltransf_11   1 LdvGcGtGrlaeala....krg..arvvgvDlskemlklakekaseeglkvefvvadaek.lpfednsfDlvvssevlhhv..e.........d 76 
                      Ld+GcG+G+  e l     + g  +  +g+D+s+ ml++a ++ +e +l      ad+ + +pf+ +sfD+ +s ++++++  +         +
       EEA20824.1  52 LDLGCGSGLSGEILSsvppDEGgpHMWIGMDVSPSMLDVALQREVEGDL----FLADIGQgVPFRPGSFDAAISISAIQWLcnAetsdvspegR 141
                      8**************99996667*****************999998874....899999978*******************8615777888889 PP

                      HHHHHHHHHHHEEEEEEEEE CS
  Methyltransf_11  77 pekalkeiaRvLkpgGllvi 96 
                      ++++++ +   L+ gG+ v+
       EEA20824.1 142 LNRFFEGLFASLRRGGRAVC 161
                      99999999999999999875 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.0   0.0   2.1e-12   4.2e-09       1      82 [.      51     133 ..      51     157 .. 0.75

  Alignments for each domain:
  == domain 1  score: 37.0 bits;  conditional E-value: 2.1e-12
                      EEEET-TTSHHHHHHHCTS....TSSEEEEEESSHHHHHHHHHHHHHTTTTEEEEESBC.CGBSSSTTTEEEEEEESTGGGSSHHHH CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrl....gkakvtgvDiseemleaareraeeeglnvefvqgda.edlpfedgsfDlvvssgalhhlsdedl 82 
                      +LdlGcG+G   + l+       g + ++g+D+s++ml+ a +r     ++ ++  +d+ + +pf  gsfD+ +s+ a+++l ++++
       EEA20824.1  51 ILDLGCGSGLSGEILSSVPpdegGPHMWIGMDVSPSMLDVALQRE----VEGDLFLADIgQGVPFRPGSFDAAISISAIQWLCNAET 133
                      8********8888777664665459****************9999....78899*****666*************877886443333 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0   3.4e-07   0.00067       7      85 ..      51     130 ..      45     185 .. 0.75

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 3.4e-07
  Methyltransf_31   7 vlDlGCGtGeltfelae....elgpkaevvGiDiseeaielArenaqklgldnveFeqgdiee.leklledekfDlilsnevl....n 85 
                      +lDlGCG+G  +  l +    e gp    +G D s+ ++ +A ++     ++   +  +di +  +  + + +fD  +s +++    n
       EEA20824.1  51 ILDLGCGSGLSGEILSSvppdEGGP-HMWIGMDVSPSMLDVALQRE----VE-GDLFLADIGQgVP--FRPGSFDAAISISAIqwlcN 130
                      8*******99999999777644444.448***************83....32.4467899999999..99999999998887766552 PP

>> PCMT  Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   2.4e-06    0.0047      58     110 ..      32      87 ..      14      99 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 2.4e-06
                 -HHHHHHHHHHTT--TT-EEEEES-TTSHHHHHHHHHHCTTC...EEEEEESBHHH CS
        PCMT  58 aphmvalalellelkkgarvLevGsGsGyltavlarlvgekg...rvvsierikel 110
                 +  m  +alell+lk  + +L++G+GsG    +l+ +  ++g     ++++ ++++
  EEA20824.1  32 QADMTHRALELLDLKSPSLILDLGCGSGLSGEILSSVPPDEGgphMWIGMDVSPSM 87 
                 45688899**********************99999887666655555666655555 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.0   4.1e-06    0.0082       1      98 [.      52     158 ..      52     159 .. 0.66

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 4.1e-06
  Methyltransf_12   1 LeiGcGtGsllrallekl.....pdieytgvDispsaiedakeklakrennnnnnvelealdlldldgg..ssfDlvvasnvlhhl........ 79 
                      L++GcG+G    ++l +       +   +g+D+sps+++ a ++  + +       ++ +           +sfD+ ++++++++l        
       EEA20824.1  52 LDLGCGSGLSG-EILSSVppdegGPHMWIGMDVSPSMLDVALQREVEGDLF---LADIGQGVP-----FrpGSFDAAISISAIQWLcnaetsdv 136
                      8*****98544.44444447775445555*********6666665555542...333333332.....1225*************988888777 PP

  Methyltransf_12  80 ...kdirevldnirklLkpgGr 98 
                           ++++++ + + L+ gGr
       EEA20824.1 137 speGRLNRFFEGLFASLRRGGR 158
                      7777777777777777777775 PP

>> Ubie_methyltran  ubiE/COQ5 methyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00013      0.26      44     119 ..      44     118 ..      14     134 .. 0.78
   2 ?    0.3   0.0      0.18   3.7e+02      43      81 ..     192     230 ..     163     262 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00013
                      -S--TTEEEEES-TT-HHHHHHHHHH.HHHH...EEEEEES-HHHHHHHHHHHHHHTSSTEEEEE--TTT-TTS-T-EEE CS
  Ubie_methyltran  44 avkrgakvlDvagGtgDlafklsdsv.gekg...kvvvlDinenmLkvgekklkeegkinieflqanaeeLpfeddsfDv 119
                        k+++ +lD+ +G+g    ++++sv  ++g     +++D++++mL+v+ ++  e       fl   ++ +pf  +sfD 
       EEA20824.1  44 DLKSPSLILDLGCGSGLSG-EILSSVpPDEGgphMWIGMDVSPSMLDVALQREVEGDL----FLADIGQGVPFRPGSFDA 118
                      4578899********9555.555555145557867789***********999776554....777778888888888885 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.18
                      --S--TTEEEEES-TT-HHHHHHHHHHHHHHEEEEEES- CS
  Ubie_methyltran  43 vavkrgakvlDvagGtgDlafklsdsvgekgkvvvlDin 81 
                       ++k+g++ l ++ G g l  +++  vg    v+++D  
       EEA20824.1 192 PGTKNGKTYLVLTVGGGGLNGDITGVVGGMDGVDIVDSR 230
                      578999999999999999999999999988888888854 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00013      0.25       9      60 ..      35      91 ..      26     182 .. 0.55

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00013
  Methyltransf_23  9 lsdklerllpklraggrvLdiGcGtGillevlre.....ngfsvt.gvDlspeaveia 60
                     + +  ++ll+ l++++ +Ld+GcG+G   e+l+       g ++  g+D sp + + a
       EEA20824.1 35 MTHRALELLD-LKSPSLILDLGCGSGLSGEILSSvppdeGGPHMWiGMDVSPSMLDVA 91
                     4444555665.89999**********87777754222213455555999999887765 PP

>> CMAS  Mycolic acid cyclopropane synthetase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.0   0.00071       1.4      42      74 ..      27      59 ..      18      65 .. 0.88
   2 ?    0.3   0.0      0.18   3.5e+02     141     169 ..     138     166 ..     111     183 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00071
                -HHHHHHHHHHHHHTTTT--TT-EEEEES-TTS CS
        CMAS 42 tLeeAqlaKldlileklelkpGmtlLdiGcGWG 74
                 + + q + ++++le l+lk  + +Ld+GcG G
  EEA20824.1 27 RIRNIQADMTHRALELLDLKSPSLILDLGCGSG 59
                56778999999********************88 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.18
                 SGGGHHHHHHHHHHHS-TT-EEEEEEEEE CS
        CMAS 141 gkenydtffkklkkllkedGllllhtits 169
                  + ++++ff+ l+  l+++G+ + +   +
  EEA20824.1 138 PEGRLNRFFEGLFASLRRGGRAVCQFYPK 166
                 4568999*************988776554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (281 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       435  (0.0242624); expected 358.6 (0.02)
Passed bias filter:                      359  (0.0200234); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.49u 0.24s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2010.93
//
Query:       EEA20825.1  [L=237]
Description: Golgi apparatus and endoplasmic reticulum protein Svp26, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-93  312.2   0.3    1.9e-93  312.0   0.3    1.0  1  Erv26     Transmembrane adaptor Erv26
  ------ inclusion threshold ------
        0.3   11.4   4.2       0.26   11.6   0.9    2.7  2  DUF1970   Domain of unknown function (DUF1970)


Domain annotation for each model (and alignments):
>> Erv26  Transmembrane adaptor Erv26
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  312.0   0.3   2.1e-97   1.9e-93       1     206 []       1     216 [.       1     216 [. 0.92

  Alignments for each domain:
  == domain 1  score: 312.0 bits;  conditional E-value: 2.1e-97
       Erv26   1 mwilellsylglvlgflfltlaiasgLyYlsElvEEhtvlakrllkrliyaiiaiqvllllvdkfpltltllsivshvvylqnlrrfPvvkltdplfll 99 
                 mwil+l++y g+v+gf+fltlaiasgLyYlsElvEEhtv+a+r+l rliy +iaiqvll+l+d+fpltl+llsi+sh+vy++nlr+fP+vkl+dplf+l
  EEA20825.1   1 MWILPLVGYTGVVVGFAFLTLAIASGLYYLSELVEEHTVIARRILYRLIYGVIAIQVLLWLFDNFPLTLSLLSIFSHLVYASNLRKFPIVKLSDPLFIL 99 
                 9************************************************************************************************** PP

       Erv26 100 scvlvvlnhylwfrhFskk.....qarlkkessy....ykkkkdvpsfteiasffglcvWlvPfalfvsLsAgdnvLPtmgsesasgessssssese.. 187
                 sc++v+lnh++wfrhFs++     +   ++++s+    + + +++p+fte+as+fglcvWlvPfalfvsLsAgdnvLP++gse+a+g++ +ss++    
  EEA20825.1 100 SCLMVCLNHWVWFRHFSRPpvpssS--SRDATSWrrpyQPDYENMPTFTEVASYFGLCVWLVPFALFVSLSAGDNVLPSIGSEYATGTTPASSTSLPes 196
                 ******************9887431..33334555553666778*****************************************99887766554456 PP

       Erv26 188 .kkkkkkkgllkavvdkvre 206
                  + ++k++gl+ka+vd+vre
  EEA20825.1 197 gSGRNKNVGLAKALVDSVRE 216
                 799***************96 PP

>> DUF1970  Domain of unknown function (DUF1970)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.1      0.26   2.3e+03       5      23 ..      44      62 ..      41      83 .. 0.75
   2 ?   11.6   0.9   2.9e-05      0.26       6      37 ..      96     129 ..      92     224 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.26
                SHHHHHHHHHHHHHHHHHH CS
     DUF1970  5 llvvvgvllvllliwlwir 23
                +l+ +  +++++ + lw+ 
  EEA20825.1 44 ILYRLIYGVIAIQVLLWLF 62
                6777777888888888875 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 2.9e-05
                 HHHHHHHHHHHHHHHHHHH..TT-S-SS-TT--- CS
     DUF1970   6 lvvvgvllvllliwlwirr..rpavdvasnweGr 37 
                 l++++ l+v l  w+w+r+  rp+v  +s+ +  
  EEA20825.1  96 LFILSCLMVCLNHWVWFRHfsRPPVPSSSSRDAT 129
                 56778899**********6559**9877665544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (237 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       554  (0.0308997); expected 358.6 (0.02)
Passed bias filter:                      338  (0.0188521); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.23s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 1700.70
//
Query:       EEA20826.1  [L=1269]
Description: Rho GTPase activator (Bem3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.7e-41  140.5   0.1    7.5e-41  139.5   0.1    1.5  1  RhoGAP    RhoGAP domain
    1.4e-13   51.2   0.0    3.1e-13   50.2   0.0    1.6  1  PH        PH domain
  ------ inclusion threshold ------
      0.048   13.0   2.8      0.085   12.2   2.8    1.3  1  DUF2353   Uncharacterized coiled-coil protein (DUF2353)
       0.12   12.7   0.0        0.7   10.2   0.0    2.1  2  PH_8      Pleckstrin homology domain


Domain annotation for each model (and alignments):
>> RhoGAP  RhoGAP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.5   0.1   1.7e-44   7.5e-41       1     146 [.     960    1108 ..     960    1111 .. 0.97

  Alignments for each domain:
  == domain 1  score: 139.5 bits;  conditional E-value: 1.7e-44
                  BHHHHHHHHHHHH.HTTTSTTTTTS-S-HHHHHHHHHHHHHTGGGCT..TTTTSCHHHHHHHHHHHHHHSSSTTTTGGHHHHHHHHHTSSSHHHHHH CS
      RhoGAP    1 Piivekcvefiek.rgldtegiyRvsgskarvkelreafdkgkavds..dleeedvhavaslLKrfLrelpepLltkelyeelieaaksedeeerle 94  
                  P++v++c+e++e+ ++  +egi+R+sgs+ ++k+l+e+f+++ +vd    ++++dvhavasl+K++Lrelp+ +lt el +e+ ++ + +d++++++
  EEA20826.1  960 PAVVYRCIEYLEAkKAASEEGIFRLSGSNLVIKALKERFNTEGDVDFlaGDHYYDVHAVASLFKQYLRELPTTVLTLELQSEFRRVPELDDHDQKIR 1056
                  99**********96679****************************999999********************************************** PP

                  HHHHHHTTS-HHHHHHHHHHHHHHHHHHHTHHHH---HHHHHHHHHHHHHT- CS
      RhoGAP   95 alkellekLPkenrdtLryLlehLkrvaenskenkMtaknLaivfaPtLlrp 146 
                  al+ l++ LPk+n ++L +L + L ++++ns++nkMt++n++ivfaPtL  p
  EEA20826.1 1057 ALNTLVHMLPKPNLSLLMALSQYLITIINNSDVNKMTVRNIGIVFAPTLNIP 1108
                  *************************************************876 PP

>> PH  PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.2   0.0   6.8e-17   3.1e-13       2     101 ..     660     769 ..     659     773 .. 0.85

  Alignments for each domain:
  == domain 1  score: 50.2 bits;  conditional E-value: 6.8e-17
                 EEEEEEEEETSSSSCSEEEEEEEEETTEEEEESSTTCTTESSEEEEEESTTEEEEEEEC............TTSSSSTSEEEEEESTSSS..T...EEE CS
          PH   2 vkeGwLlkkgsgkkkswkkrwfvLkdsellyykndksekdkepkgsislsncevvevva............tedpkrkfcfelriverng..s...rty 83 
                  keG+L+k+g++++ +wk r+fvL++ el y++ +         g+i + n+++ +  +            ++d + ++ f +  +  ++  +    ++
  EEA20826.1 660 RKEGYLTKRGKNFG-GWKSRYFVLHGPELKYFEGP----GGAHLGTIKIPNAQIGKQSQgghnqspsraedDSDNQYRHAFLILEP--KKkdTsalVRH 751
                 69************.********************....*****************999********9964336666666666333..33332456*** PP

                 EEEESSHHHHHHHHHHHH CS
          PH  84 llqasseeerkeWikaiq 101
                 +l+a+s+ er +W+ a+ 
  EEA20826.1 752 VLCAESDAERDSWVDALL 769
                 ***************995 PP

>> DUF2353  Uncharacterized coiled-coil protein (DUF2353)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   2.8   1.9e-05     0.085       5      89 ..     115     200 ..     112     207 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 1.9e-05
     DUF2353   5 esKveALli.LskeLekcrqerdqyklmaeqLqerlsalkkqleeekakaadlkeekekekklsqlleesreenkalkleveeLrq 89 
                   K+ AL++ L+++Le++ +++d+yk ++++Lq++   l +++++    ++  +++++++++++  +++ ++  ++ + +  + +q
  EEA20826.1 115 LEKQRALVLgLNRDLERAIKDKDRYKKKLKELQSQAPPLPTNNQQSLPLREGSSKDQKSNETTIVDVSNRQHSDSSRQDDSPNTQQ 200
                 4577787655****************************999999999988888888777777777777666666666666655555 PP

>> PH_8  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   0.00016       0.7       5      50 ..     666     708 ..     663     716 .. 0.83
   2 ?   -1.1   0.0      0.53   2.4e+03      70      85 ..     753     768 ..     745     771 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00016
        PH_8   5 kkrrkklqgyakRfFvLdlksstlsYyrddnssalrgkiplslaii 50 
                  kr k   g++ R+FvL  +  +l+Y++   +++l g i +  a i
  EEA20826.1 666 TKRGKNFGGWKSRYFVL--HGPELKYFEGPGGAHL-GTIKIPNAQI 708
                 5889999**********..999******9999888.8888777655 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.53
        PH_8  70 LkasnekdfqeWveal 85 
                 L a+++++ ++Wv+al
  EEA20826.1 753 LCAESDAERDSWVDAL 768
                 78999**********8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1269 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       875  (0.0488036); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.81u 0.31s 00:00:01.12 Elapsed: 00:00:00.47
# Mc/sec: 8171.01
//
Query:       EEA20827.1  [L=704]
Description: mitochondrion biogenesis protein (Mdm31), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
   3.6e-253  841.0   0.1   4.6e-253  840.7   0.1    1.1  1  MDM31_MDM32  Yeast mitochondrial distribution and morphology 
     0.0086   15.7   0.4      0.015   15.0   0.4    1.3  1  TraH_2       TraH_2


Domain annotation for each model (and alignments):
>> MDM31_MDM32  Yeast mitochondrial distribution and morphology (MDM) proteins
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  840.7   0.1  5.1e-257  4.6e-253       1     525 []     179     699 ..     179     699 .. 0.94

  Alignments for each domain:
  == domain 1  score: 840.7 bits;  conditional E-value: 5.1e-257
  MDM31_MDM32   1 keelLaaangflsrlkirlkwllirsvrpfnaddisafvswlllgnvlwillgtTtfvslvillintvfaqetlakkigdyltkstgvkvvFEsaivp 98 
                  keelLaaa+gf+srl++r+kw++irsvrpf  d+i+a++sw+llg+vlwi+lgtTtf+sl+il+intvfaqetla+++g+ylt+s+gv+vvFEsaivp
   EEA20827.1 179 KEELLAAATGFWSRLRVRFKWFSIRSVRPFTLDEIGALFSWVLLGHVLWIILGTTTFFSLLILTINTVFAQETLARWVGNYLTSSSGVQVVFESAIVP 276
                  89************************************************************************************************ PP

  MDM31_MDM32  99 kwkdgkisfknvfvsrrPkqkkskvekgsskeaaakaaaaaaaeekese..eeeeeeeddgnytqfdltidtvdvtLsfakwlngkGllkdvevkGvr 194
                  kw+dg+i+fknvfvsrrP++ + +v+kgssk+aaa+aaaaa+a+++++e  +++++ e+d+nytqfd++idtv+vtLsf+kw+ngkGll+dvevkG+r
   EEA20827.1 277 KWRDGVITFKNVFVSRRPGHGNGHVSKGSSKTAAAAAAAAASATSDSKEtdSNHAAVEEDSNYTQFDVSIDTVNVTLSFTKWFNGKGLLRDVEVKGIR 374
                  ********************************99988877766444444346666679**************************************** PP

  MDM31_MDM32 195 GvvdrthvkwkeeeldpksyrhehqpgdfelesfkledvlvtvyqpegfrpfkvsifscdlpqLRkqwlfyDflsAnnvsGsfdnslFtiHkrqs... 289
                  Gv+drthv+w++ + dpksyr eh+pgdfe++sfk+ed+lvtvyqp++frpf vsifscdlpqLRkqwlfyDflsAn++sGsfdnslFtiH+rq+   
   EEA20827.1 375 GVIDRTHVHWTDYNADPKSYRREHNPGDFEIDSFKMEDLLVTVYQPNNFRPFAVSIFSCDLPQLRKQWLFYDFLSANMMSGSFDNSLFTIHPRQTnnf 472
                  ************99*********************************************************************************777 PP

  MDM31_MDM32 290 ...lekeeeekeeea......skwkklsrlridglnidhlnrgvegpfsWiteGkvdivaDimlPededelslskvlseildkleeevtskkaleeee 378
                     +  +++            ++wkk+sr+ridglnidhlnrgvegpfsWi+eG+vdivaDimlP+d+ e sl+k++s+++d++e++vts++++    
   EEA20827.1 473 tgaQ-LTSS-----GeetvkgTPWKKQSRIRIDGLNIDHLNRGVEGPFSWIHEGNVDIVADIMLPADDSE-SLAKFVSDFYDRFEATVTSHSHT---- 559
                  6531.2222.....12223469********************************************9988.9*******************943.... PP

  MDM31_MDM32 379 kseelakeaksaeeseeekeeeeekeeeeeekyvvvdlklklndvkAavPlftkdlsyvnnaliRpivayiNskrtyipikcrvvkklsdfdgswtvy 476
                          ++++  ++ ++++    ++e++++++v dl+l+l +v+A vPlftkdlsy+n+aliRpivayiNs++t+ipi+cr+vk+lsdfdgswtv+
   EEA20827.1 560 -------GETNECPQDANTPSLIPVDDENDKRFFVTDLRLHLTNVRAVVPLFTKDLSYINSALIRPIVAYINSRHTFIPIHCRLVKRLSDFDGSWTVF 650
                  .......33445556666677778889999******************************************************************** PP

  MDM31_MDM32 477 dsgLmddlsaevYealakdvadeearkrrlkkvglWslqlavqalllgl 525
                  dsgLmddlsa +Y+a+a+dv de+ar+rr+kkvg+Wslqla+qa++lg+
   EEA20827.1 651 DSGLMDDLSAATYDAFAADVVDEQARMRRFKKVGFWSLQLAAQAIFLGM 699
                  ***********************************************97 PP

>> TraH_2  TraH_2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.4   1.6e-06     0.015     112     198 ..     252     342 ..     242     352 .. 0.64

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.6e-06
      TraH_2 112 vakwyGnp.keddvlpqifedave.awktGefeGvsvfqaadpGkvv..ateealgaededvkekdsaklktadadteleekeddvnkagi 198
                 +a+w Gn  +++  +  +fe a++  w+ G    ++vf +  pG+ +  + +++ ++ + ++  ++sa  ++ ++d+++ + e+d n +++
  EEA20827.1 252 LARWVGNYlTSSSGVQVVFESAIVpKWRDGVITFKNVFVSRRPGHGNghVSKGSSKTAAAAAAAAASATSDSKETDSNHAAVEEDSNYTQF 342
                 689999973566678889****8747****9999999999888865411455555555555555555555555555555555555554433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (704 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       599  (0.0334096); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.32s 00:00:00.99 Elapsed: 00:00:00.48
# Mc/sec: 4404.49
//
Query:       EEA20828.1  [L=257]
Description: rRNA processing protein (Rrp20), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.4e-05   23.5   0.0    8.5e-05   22.6   0.0    1.4  1  KH_8      Krr1 KH1 domain
     0.0021   17.9   0.5      0.017   14.9   0.3    2.3  2  KH_1      KH domain


Domain annotation for each model (and alignments):
>> KH_8  Krr1 KH1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.6   0.0   9.4e-09   8.5e-05       6      78 ..      84     157 ..      80     160 .. 0.90

  Alignments for each domain:
  == domain 1  score: 22.6 bits;  conditional E-value: 9.4e-09
        KH_8   6 lfpkyrekylkeveekikkll.eekklklevdlkerslkvsTtekTrDPyiilkardlikLisrgvpleeakkv 78 
                   p +r + lk  ++ki   l e+ kl++++++k r+++++  + T DP  + ++ d++k  + + +++ a  +
  EEA20828.1  84 PIPPHRMTPLKTYWPKIYPPLvEHLKLQVRMNVKSRTVELRNSKLTNDPSALQRGADFVKAFALSFDVDDAIAL 157
                 56899************98775889***********************************99999999888765 PP

>> KH_1  KH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0     0.077   6.9e+02      21      40 ..      43      62 ..      43      73 .. 0.76
   2 !   14.9   0.3   1.9e-06     0.017       9      65 ..     183     231 ..     180     232 .. 0.91

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.077
                HHHHHHHHH.T-EEEEESSTT CS
        KH_1 21 nIkeIreet.gakIkvpksed 40
                ++ +I+e+t g  ++v+ +e 
  EEA20828.1 43 TVESIQEDTtGDVMHVD-EEG 62
                5779***999*999987.443 PP

  == domain 2  score: 14.9 bits;  conditional E-value: 1.9e-06
                 GHHHHHHTGGGHHHHHHHHHHT-EEEEESSTT...T.-EEEEEESHHHHHHHHHHHH CS
        KH_1   9 slvgriIGkgGsnIkeIreetgakIkvpksedegsderevtisGspeavekAkelie 65 
                 + +gri G +G++   I++ t +++++  ++        v+i G+ ++ + A+e+i 
  EEA20828.1 183 RAIGRIAGHNGKTKFAIENATRTRVVLA-GQ-------KVHILGTFKNAKMAQEAIV 231
                 679***********************76.54.......5***************995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (257 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       437  (0.0243739); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1771.68
//
Query:       EEA20829.1  [L=252]
Description: proteasome component Prs3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.5e-30  106.1   0.1    4.5e-30  104.5   0.1    1.8  1  Proteasome  Proteasome subunit


Domain annotation for each model (and alignments):
>> Proteasome  Proteasome subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.5   0.1   2.5e-34   4.5e-30       2     154 ..      27     181 ..      26     237 .. 0.93

  Alignments for each domain:
  == domain 1  score: 104.5 bits;  conditional E-value: 2.5e-34
                 HHS-EEEEEEETTEEEEEEEEEEEETTEEEESSSSTSEEEE..ET......TEEEEEEESHHHHHHHHHHHHHHHHHHHHHHSSGTCHHHHHHHHHHHH CS
  Proteasome   2 kkGttvvGikgkdgvvlaadkratagskllskstveKifki..dd......higvafaGlaaDartlvrraraeaqlyrlrygrpipverlvarvaakl 92 
                 ++G++++Gi+g+d+ +la+d+r+t+g  + ++  + K+fki  dd      hi+++++G aaD+ +l +r+ + ++ yr+++g+pi+v     ++a++l
  EEA20829.1  27 DNGGSTLGIAGSDFCILAGDTRSTSGYNINTRY-APKLFKIggDDetgegaHIVLSVVGFAADGHALKERLDSIVKVYRYQHGKPITVN----ACAQRL 120
                 68***************************7777.8******64336677779*************************************....999999 PP

                 HHHHHHCTTTTTSEEEEEEEEETTTEEEEEEEETTSEEEEESSEEEESTTHHHHHHHHHHHH CS
  Proteasome  93 qaytqrsgrrpfgvslliagvdeeggpeLyqidpsGsyieekdavaiGsgseaaktalekey 154
                 +  ++++++ p+++ ++++g+deeg+  Ly+ dp Gsy +e ++ a+G +s  ++++l++++
  EEA20829.1 121 STILYSKRFFPYYAYAILGGLDEEGRGALYSYDPVGSYERE-QCRAAGAASSLIMPFLDNQV 181
                 9999999**********************************.5****************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (252 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       358  (0.0199677); expected 358.6 (0.02)
Passed bias filter:                      349  (0.0194657); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 1826.93
//
Query:       EEA20830.1  [L=224]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.1e-28   96.9   0.1    1.4e-27   96.1   0.1    1.4  1  HCNGP     HCNGP-like protein


Domain annotation for each model (and alignments):
>> HCNGP  HCNGP-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   96.1   0.1     8e-32   1.4e-27       1      93 [.     109     204 ..     109     205 .. 0.96

  Alignments for each domain:
  == domain 1  score: 96.1 bits;  conditional E-value: 8e-32
       HCNGP   1 iPpsppskcdpelqaKiekflklkkegvhfnerlassksfrNPsilekLvefvgi...deygtnlpkevwdphgfpeeayydalakaqkkerekre 93 
                 +Ppspp++ dp ++ K ++fl+lkk+gvhfne+l++s+s++NPs++ kL e+ gi   ++y+t+lp+++wd +++p++ay+++l k q+++r+k e
  EEA20830.1 109 LPPSPPGSPDPIASGKATQFLALKKQGVHFNEKLSASSSLKNPSLFLKLREHTGIddvSQYATSLPSDIWDHTSLPAWAYKEELYKMQQAIRSKIE 204
                 7*****9899*********************************************77669*****************************9998865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (224 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       410  (0.022868); expected 358.6 (0.02)
Passed bias filter:                      295  (0.0164538); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.24s 00:00:00.63 Elapsed: 00:00:00.39
# Mc/sec: 1736.39
//
Query:       EEA20831.1  [L=260]
Description: proteasome component Pre4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.5e-28   99.6   0.0    1.8e-28   99.4   0.0    1.1  1  Proteasome  Proteasome subunit


Domain annotation for each model (and alignments):
>> Proteasome  Proteasome subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.4   0.0   9.8e-33   1.8e-28       3     190 .]      39     228 ..      37     228 .. 0.91

  Alignments for each domain:
  == domain 1  score: 99.4 bits;  conditional E-value: 9.8e-33
                 HS-EEEEEEETTEEEEEEEEEEEETTEEEESSSSTSEEEEETTEEEEEEESHHHHHHHHHHHHH.HHHHHHHHHSSGTCHHHHHHHHHHHHHHHHH..H CS
  Proteasome   3 kGttvvGikgkdgvvlaadkratagskllskstveKifkiddhigvafaGlaaDartlvrrara.eaqlyrlrygrpipverlvarvaaklqaytq..r 98 
                 +Gt+vv++k+++gv++a+d+ a++gs    ++ v++i+  dd  +v+f G+++D++++ r + + ++++    +g  ++ +    ++ ++l++  +  r
  EEA20831.1  39 TGTSVVAVKFNGGVAMATDNLASYGSLARFTD-VNRIRTFDDSAIVGFGGDVSDMQYIDRLLGSiQIRENYSATGSTLNAK----NLHTYLSKVFYkrR 132
                 7***************************9999.9************************99987735666666788889888....55555544444226 PP

                 CTTTTTSEEEEEEEEETTTEEEEEEEETTSEEEEESSEEEESTTHHHHHHHHHHHH.....STTBSHHHHHHHHHHHHHHHHHHBTTSCSSEEEEEE CS
  Proteasome  99 sgrrpfgvslliagvdeeggpeLyqidpsGsyieekdavaiGsgseaaktalekey.....kedltleeavelavkalkealerdklsgknievavi 190
                 s ++p+  ++l+ag+d +g+p+L + d  G+ ++  +  a+G g++ a ++l++++      e++++e+a++  + ++k +++rd+ s +++++avi
  EEA20831.1 133 SEMNPLWNHILVAGFDSDGKPFLSSADLLGTTYSG-PHLATGFGAHLAVPILRRLFpeeipIENISKEQAIKALRDCMKVLFYRDARSMDQYTLAVI 228
                 789********************************.6********************99999********************************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (260 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       532  (0.0296726); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.21s 00:00:00.65 Elapsed: 00:00:00.38
# Mc/sec: 2048.76
//
Query:       EEA20832.1  [L=498]
Description: heat shock protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.9e-18   64.7   2.1      3e-17   62.4   2.7    1.9  2  Complex1_LYR    Complex 1 protein (LYR family)
    3.6e-15   56.0   4.8    7.3e-12   45.3   0.3    3.0  3  HSP20           Hsp20/alpha crystallin family
    6.7e-07   30.0   0.1    1.4e-06   29.0   0.1    1.5  1  Complex1_LYR_2  Complex1_LYR-like
    1.8e-06   27.4   0.0    0.00096   18.7   0.0    2.3  2  ArsA_HSP20      HSP20-like domain found in ArsA
  ------ inclusion threshold ------
      0.092   13.4   0.2       0.21   12.2   0.2    1.6  1  Complex1_LYR_1  Complex1_LYR-like


Domain annotation for each model (and alignments):
>> Complex1_LYR  Complex 1 protein (LYR family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.4   2.7   8.3e-21     3e-17       1      58 [.     105     163 ..     105     164 .. 0.95
   2 ?   -2.2   0.0       1.3   4.5e+03      30      44 ..     364     378 ..     361     381 .. 0.86

  Alignments for each domain:
  == domain 1  score: 62.4 bits;  conditional E-value: 8.3e-21
  Complex1_LYR   1 rqvLsLYRalLRearkfpdyntreyfrrriRdeFrknkh..vtDpekieellkkgreeLe 58 
                   r+vLsLYR++LReark+p ++ r++fr+ ++ eFrk  +   +D++ ie+ll+kg+++Le
    EEA20832.1 105 REVLSLYRKCLREARKKPEDT-RDHFRAFAQSEFRKQLDvnKKDFSTIEHLLRKGHKQLE 163
                   69****************999.**************9887788****************8 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.3
  Complex1_LYR  30 iRdeFrknkhvtDpe 44 
                   i+ + ++n +vt+p+
    EEA20832.1 364 IKGQIERNYDVTSPS 378
                   778889******998 PP

>> HSP20  Hsp20/alpha crystallin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0      0.63   2.3e+03      40      66 ..     120     145 ..      81     163 .. 0.70
   2 !   13.3   0.7     2e-05     0.071       1      92 [.     330     429 ..     330     435 .. 0.71
   3 !   45.3   0.3     2e-15   7.3e-12      23     101 ..     418     497 ..     407     498 .] 0.87

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.63
                 ..---TT----SS---EEEEEE--STT CS
       HSP20  40 eeeedekglikerssrkFsrkftLPen 66 
                 ++ ed +++ +  ++++F++++ + + 
  EEA20832.1 120 KKPEDTRDHFRAFAQSEFRKQLDV-NK 145
                 345666666666888999988877.44 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 2e-05
                 E--SSEEEEEEEEE-TT--CCCEEEEEETTE.EEEEEE--..........---TT----SS---EEEEEE--STTB-TTT-EEEEETTEEEEEEEBSS- CS
       HSP20   1 dikeeeeefevkldvpglkkeelkvkvednr.vlvkgehe........eeeedekglikerssrkFsrkftLPenvdadkvkaslkdGvLtvtvpkkep 90 
                 d++e ++ + ++ ++pg ++e+++++ +d++ +++kg+ e        + ee+ ++    +s+ + s + +   n+   +v+ + +dGv +v++ ++++
  EEA20832.1 330 DVREADQFYILNGELPGAQQENIEIEFTDTEtMVIKGQIErnydvtspSSEESTHDNDDVMSVHSDS-ASSTHSNYHSPTVEDEDEDGVVKVKAAQSTS 427
                 5678899999*****************99876999***99888888763333333333322233323.3333468888999988899999998888776 PP

                 -. CS
       HSP20  91 ek 92 
                 + 
  EEA20832.1 428 NV 429
                 65 PP

  == domain 3  score: 45.3 bits;  conditional E-value: 2e-15
                 EEEEEETTEEEEEEE--......---TT----SS---EEEEEE--STTB-TTT-EEEEETTEEEEEEEBSS--..-------- CS
       HSP20  23 lkvkvednrvlvkgehe....eeeedekglikerssrkFsrkftLPenvdadkvkaslkdGvLtvtvpkkepekkkkerkiqi 101
                 +kvk  + +  v  +h+     ++ + k++++ers + F+r+ft P  v++d+vka +k+G+L+v vpk+  +   k ++i +
  EEA20832.1 418 VKVKAAQSTSNVATKHQpqseAQQPKYKYWASERSIGTFQRTFTFPTRVNQDEVKAVFKNGILSVFVPKQAIQ---KAKRIRV 497
                 678888888888888888887788899******************************************9988...5677766 PP

>> Complex1_LYR_2  Complex1_LYR-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.0   0.1   3.8e-10   1.4e-06       1      51 [.     107     159 ..     107     186 .. 0.79

  Alignments for each domain:
  == domain 1  score: 29.0 bits;  conditional E-value: 3.8e-10
  Complex1_LYR_2   1 vlsLYrrllrelrelppelrslgdayvraefrrhkhlk.npe...eialflknqr 51 
                     vlsLYr  lre+r++p++ r +++a  ++efr+  +l+ n++    i  +l++ +
      EEA20832.1 107 VLSLYRKCLREARKKPEDTRDHFRAFAQSEFRK--QLDvNKKdfsTIEHLLRKGH 159
                     79***********99******************..44444440025556665554 PP

>> ArsA_HSP20  HSP20-like domain found in ArsA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.3   0.0    0.0019       6.9       4      32 ..     338     367 ..     335     393 .. 0.81
   2 !   18.7   0.0   2.7e-07   0.00096      30      61 ..     452     482 ..     451     483 .. 0.96

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0019
  ArsA_HSP20   4 yvlkldLPfvdkeeidlsrs.gdeLtIkig 32 
                 y+l+ +LP++++e+i+++ +  ++++Ik +
  EEA20832.1 338 YILNGELPGAQQENIEIEFTdTETMVIKGQ 367
                 888999***********9873566777654 PP

  == domain 2  score: 18.7 bits;  conditional E-value: 2.7e-07
  ArsA_HSP20  30 kignfrRqitLPsvlarkevtsAkfedgvLeI 61 
                 +ig f+R++t P++++++ev +A f++g L +
  EEA20832.1 452 SIGTFQRTFTFPTRVNQDEV-KAVFKNGILSV 482
                 589*****************.*********87 PP

>> Complex1_LYR_1  Complex1_LYR-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.2   5.8e-05      0.21       1      42 [.     105     145 ..     105     166 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 5.8e-05
  Complex1_LYR_1   1 reklrlyrallkaarrfPlrsrreivaeevraafrhplndsl 42 
                     re+l+lyr+ l+ ar+ P   r        +++fr+ l+   
      EEA20832.1 105 REVLSLYRKCLREARKKPEDTRD-HFRAFAQSEFRKQLDVNK 145
                     79****************87665.556667899998876544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (498 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1061  (0.0591779); expected 358.6 (0.02)
Passed bias filter:                      571  (0.0318478); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.66u 0.32s 00:00:00.98 Elapsed: 00:00:00.52
# Mc/sec: 2887.63
//
Query:       EEA20833.1  [L=289]
Description: fumarylacetoacetate hydrolase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.1e-63  213.9   0.0    2.7e-63  213.6   0.0    1.1  1  FAA_hydrolase  Fumarylacetoacetate (FAA) hydrolase family
  ------ inclusion threshold ------
       0.17   12.8   0.2        2.2    9.2   0.1    2.7  2  DUF2437        Domain of unknown function (DUF2437)


Domain annotation for each model (and alignments):
>> FAA_hydrolase  Fumarylacetoacetate (FAA) hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  213.6   0.0     3e-67   2.7e-63       2     217 ..      72     280 ..      71     281 .. 0.95

  Alignments for each domain:
  == domain 1  score: 213.6 bits;  conditional E-value: 3e-67
                    EEEEEEE--SHHHHHTTT.-SS-EEEEEEGGGE.EETTE..EE-TTSSSS-EE.........EEEEEEEESS-B--T--HHHHHTTEEEEEEEEEE CS
  FAA_hydrolase   2 ivcdglnyaehvreagkaaeeppdrhiplepvfflkrasslvgpgdpirrPagsek...ldyEvELavvigkplrevlsveeAedaiaGytllnDv 94 
                    + c glny++h+ e +    + p+      pv+f+k+ +s+ gp d+i++ + +++   ldyE+EL+v+igk++r+v + ++A d+++Gy+++nDv
     EEA20833.1  72 VRCLGLNYEQHAIESN---APIPK-----YPVLFYKPVTSIAGPTDDIPVSYMAQEgegLDYECELVVIIGKEARDV-PESKALDYVFGYAVGNDV 158
                    5699**********84...56666.....899****************99999555555******************.9***************** PP

                    E-SBGGG---.HHHHHHTGGGEEEEEE-B--B-.STT---SS-EEEEEETTEEEEEEEGGGTTTSHHHHHHHHHHHH-B-TT-EEEEEES...... CS
  FAA_hydrolase  95 saRdlqaeekaplgwflgksfdtftpiGpwivtpdeledpedlelrlrvngeevqdsntkdmifspaeliahlsagltLepGdliltGTpsgvgae 190
                    s Rd+q ++    +w lgk+fd+ +p+Gp iv+ + ++dp++le+++ +nge vq+sntkd if++a+ ia +s+g+tL pGd+i+tGTp+gvg +
     EEA20833.1 159 SHRDWQIKKG-GGQWSLGKGFDGWAPFGPGIVSSKLIRDPNALEISTKLNGEIVQSSNTKDQIFGVAKTIAFISQGVTLLPGDVIFTGTPQGVGMG 253
                    ******9999.77*********************************************************************************99 PP

                    .S--EE--TT-EEEEEETTTEEEEEEE CS
  FAA_hydrolase 191 eeslkflkdgDeveveieglGelrnrV 217
                    ++++ +lkdgD vev+++++G++ nrV
     EEA20833.1 254 RKPQLWLKDGDYVEVSLQDVGTCSNRV 280
                    **************************9 PP

>> DUF2437  Domain of unknown function (DUF2437)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.1   0.00025       2.2       2      48 ..       6      60 ..       5      63 .. 0.81
   2 ?   -1.9   0.0      0.77   6.9e+03      20      37 ..     232     245 ..     213     249 .. 0.60

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00025
                EEEEE.EETTEEEEEEEE...........EEEEEESS-TTSS-EEEEEEEEGGGSEEE CS
     DUF2437  2 riaRF.shgggpryGvle..........gdtvvvlagdpfgavqpTGervpLadVrLL 48
                r++RF +++g++ yG              ++ +v++gd fg+   T++    a+V+LL
  EEA20833.1  6 RLVRFlAKDGQVYYGDAIlpsgktdiaqITKARVIKGDIFGEHHVTDQ---IAEVKLL 60
                8999988888999986656688888888889999999****9999999...6999665 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.77
                 EEEEEESS-TTSS-EEEE CS
     DUF2437  20 dtvvvlagdpfgavqpTG 37 
                 + v++l gd    v +TG
  EEA20833.1 232 QGVTLLPGD----VIFTG 245
                 445666664....44444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (289 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       223  (0.0124379); expected 358.6 (0.02)
Passed bias filter:                      218  (0.0121591); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.43
# Mc/sec: 2040.71
//
Query:       EEA20834.1  [L=521]
Description: hypothetical protein PMAA_046530 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (521 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       536  (0.0298957); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                         9  (0.00050198); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.40
# Mc/sec: 3905.11
//
Query:       EEA20835.1  [L=232]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.8e-11   43.8   0.2    4.9e-11   43.0   0.2    1.4  1  Autophagy_act_C  Autophagocytosis associated protein, active-


Domain annotation for each model (and alignments):
>> Autophagy_act_C  Autophagocytosis associated protein, active-site domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.0   0.2   2.7e-15   4.9e-11       1      55 []     119     189 ..     119     189 .. 0.90

  Alignments for each domain:
  == domain 1  score: 43.0 bits;  conditional E-value: 2.7e-15
  Autophagy_act_C   1 ItYsktYqvPvlyfrlyd.edgtplsleelyed.................sadvtieehpllgvpwysiHPCk 55 
                      I +s++Y+vPv+yf l + ++  p  l+++y+                  +  ++ + hp +g+p y++HPC+
       EEA20835.1 119 IALSTSYHVPVMYFCLREtPQVGPAALDDIYNFlvprqhqqslrnngvmgG--ISFGYHPKSGIPAYFVHPCN 189
                      789*************9965567888***************9999865555..*******************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (232 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       258  (0.0143901); expected 358.6 (0.02)
Passed bias filter:                      248  (0.0138323); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.25s 00:00:00.65 Elapsed: 00:00:00.40
# Mc/sec: 1757.05
//
Query:       EEA20836.1  [L=177]
Description: U1 small nuclear ribonucleoprotein A, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      8e-10   38.4   0.0      2e-09   37.1   0.0    1.7  1  RRM_1          RNA recognition motif. (a.k.a. RRM, RBD, or RN
    5.4e-05   22.8   0.0    7.4e-05   22.3   0.0    1.2  1  RRM_5          RNA recognition motif. (a.k.a. RRM, RBD, or RN
      0.008   16.0   0.0      0.013   15.4   0.0    1.3  1  RRM_occluded   Occluded RNA-recognition motif
  ------ inclusion threshold ------
       0.12   12.8   0.0       0.22   11.9   0.0    1.5  1  Prim-Pol       Bifunctional DNA primase/polymerase, N-termina
       0.13   10.3   0.0       0.15   10.1   0.0    1.1  1  FSA_C          Fragile site-associated protein C-terminus
        2.2    8.9   7.6          6    7.5   7.6    1.8  1  Ribosomal_60s  60s Acidic ribosomal protein


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.1   0.0   6.7e-13     2e-09       1      69 [.      22      92 ..      22      93 .. 0.89

  Alignments for each domain:
  == domain 1  score: 37.1 bits;  conditional E-value: 6.7e-13
                EEEESETTTSSHHHH....HHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1  1 lfVgnLppdvteeeL....kelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkklggrel 69
                l+++nLp  +++ +L    ++lFs +Gp+ ++ + +  t k +g a + + +  + ++A++al+g  + g+el
  EEA20836.1 22 LYIKNLPDKIKKPDLrmalYTLFSTYGPVLDVVVLK--TAKMRGQAHIVYRDIQASTQAMRALQGFDFFGKEL 92
                89********987751111689*******9999999..8*******************************997 PP

>> RRM_5  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.3   0.0   2.5e-08   7.4e-05      43     103 ..      39     101 ..       4     111 .. 0.84

  Alignments for each domain:
  == domain 1  score: 22.3 bits;  conditional E-value: 2.5e-08
       RRM_5  43 klFnlfclYgnvervkflktkk..etalvqmgdasaveravqHLnnaklfgkrlevalSKqqa 103
                  l+ lf+ Yg v  v +lkt k  ++a +   d +a  +a+  L++   fgk+l+++  K  +
  EEA20836.1  39 ALYTLFSTYGPVLDVVVLKTAKmrGQAHIVYRDIQASTQAMRALQGFDFFGKELNIVYAKGSS 101
                 699****************9754499*******************************999654 PP

>> RRM_occluded  Occluded RNA-recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   4.3e-06     0.013       2      71 ..      20      95 ..      19      99 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 4.3e-06
  RRM_occluded  2 rtisllplsDtvnkariralveek...egeikkivLv.p..dheGAivefkdekiagkasLaLdgsefegkklrcG 71
                  +t+ + +l+D++ k  +r  + +     g++ ++v+  +    + A ++++d ++  +a+ aL+g +f gk+l++ 
    EEA20836.1 20 QTLYIKNLPDKIKKPDLRMALYTLfstYGPVLDVVVLkTakMRGQAHIVYRDIQASTQAMRALQGFDFFGKELNIV 95
                  68999**********999877666654377777665413113456***************************9986 PP

>> Prim-Pol  Bifunctional DNA primase/polymerase, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   7.4e-05      0.22      68     146 ..      35     114 ..       4     129 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 7.4e-05
    Prim-Pol  68 agaealarLareegplPetvtvttgstgggrhlyfraPdglalpnsagklapgldlrgeg.gyvvappsvh...etgraYrwl 146
                 + ++al  L  ++gp+ + v+ +t++  g+ h+++r   +++ +++a +  +g+d+ g+  + v a +s h   +  ++Y  +
  EEA20836.1  35 DLRMALYTLFSTYGPVLDVVVLKTAKMRGQAHIVYR---DIQASTQAMRALQGFDFFGKElNIVYAKGSSHviaKLRGTYMAT 114
                 7789999999998877778999999999********...78999999999999*******8888999****766444555544 PP

>> FSA_C  Fragile site-associated protein C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   5.1e-05      0.15     522     603 ..      49     135 ..      26     154 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 5.1e-05
       FSA_C 522 pyltdevlkekkaksstsltpklmsaakssleslqg.....sqdsiaiattasavelndatsstiasaatasslsstkstvtivvst 603
                 p l   vlk +k +  + ++ + + a+++++ +lqg        +i  a+++s v ++  ++   +++a a + +st+ + +i  + 
  EEA20836.1  49 PVLDVVVLKTAKMRGQAHIVYRDIQASTQAMRALQGfdffgKELNIVYAKGSSHVIAKLRGTYMATATANAPTGASTDLQKSIFGAP 135
                 6788899***************************97332225678899*******99999999999999999999998888776654 PP

>> Ribosomal_60s  60s Acidic ribosomal protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   7.6     0.002         6      40      82 ..     117     169 ..      89     173 .. 0.66

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.002
                    XXXXXXXX........XXXXXXXXXXXXXXXXXXXXXXXXXXXX...XX--SS CS
  Ribosomal_60s  40 angaakla........aaaaaaaaaaaaaaaaaaaeekkkeeeee..Eeeddd 82 
                    an+ ++++        +a+++aa aa+ + + + +ee ++ e +   +e+d  
     EEA20836.1 117 ANAPTGAStdlqksifGAPPSAATAATVGTKRPREEESDEGEAPMdeDESDVS 169
                    33333333777777777777777777777777777777777777643345444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (177 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       424  (0.0236488); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.43u 0.25s 00:00:00.68 Elapsed: 00:00:00.40
# Mc/sec: 1341.04
//
Query:       EEA20837.1  [L=362]
Description: actin-related protein 2/3 complex subunit 1A, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    7.2e-17   61.5  12.1    0.00022   22.0   0.0    6.8  7  WD40         WD domain, G-beta repeat
    8.7e-09   35.6   0.0     0.0069   16.7   0.0    4.8  4  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
     0.0014   18.4   2.1      0.014   15.2   0.1    2.8  3  Gmad1        Lipoprotein LpqB beta-propeller domain
  ------ inclusion threshold ------
      0.033   14.5   0.1          2    8.7   0.0    2.5  2  DUF3642      Bacterial lipoprotein
      0.054   12.2   0.8        6.5    5.4   0.0    3.3  3  DPPIV_N      Dipeptidyl peptidase IV (DPP IV) N-terminal regi
       0.15   11.0   0.0         32    3.3   0.0    3.0  3  Ge1_WD40     WD40 region of Ge1, enhancer of mRNA-decapping p


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.5   0.0    0.0027         8       4      37 ..       6      37 ..       4      38 .. 0.85
   2 !   22.0   0.0   7.3e-08   0.00022       6      37 ..      49      81 ..      44      82 .. 0.92
   3 ?   -1.4   0.0       1.8   5.4e+03      16      29 ..     104     117 ..      97     120 .. 0.83
   4 !   18.3   0.4   1.1e-06    0.0032      12      37 ..     142     171 ..     133     172 .. 0.81
   5 !    7.3   0.2    0.0032       9.6      12      34 ..     207     229 ..     195     231 .. 0.81
   6 ?    4.6   0.0     0.022        65      14      34 ..     255     274 ..     248     275 .. 0.90
   7 ?    3.5   0.0     0.049   1.5e+02      25      37 ..     348     360 ..     319     361 .. 0.70

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0027
                EEEEESSSSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40  4 lrtltGHssvtslafspdgawlasGsdDgtvriW 37
                +++l  Hs++ + +fs+d++ la +  D++v ++
  EEA20837.1  6 VHHL-FHSPIADHSFSQDKSTLAVAR-DNNVELY 37
                5666.6999*************9877.***9987 PP

  == domain 2  score: 22.0 bits;  conditional E-value: 7.3e-08
                EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40  6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37
                +l+GH + vt+++  pd+  ++++s D++ ++W
  EEA20837.1 49 ELKGHdKTVTGVDIAPDSGRIVTCSQDRNAYVW 81
                699**888************************* PP

  == domain 3  score: -1.4 bits;  conditional E-value: 1.8
                 EEEETTSSEEEEEE CS
        WD40  16 lafspdgawlasGs 29 
                 +++sp+ + +a Gs
  EEA20837.1 104 VRWSPSEQKFAVGS 117
                 679***99999886 PP

  == domain 4  score: 18.3 bits;  conditional E-value: 1.1e-06
                 S....EEEEEEETTSSEEEEEETTSEEEEE CS
        WD40  12 s....vtslafspdgawlasGsdDgtvriW 37 
                 +    +t la++p++ +la+Gs D + r++
  EEA20837.1 142 PirstITTLAWHPNSVLLAAGSTDSHARVF 171
                 244459*********************997 PP

  == domain 5  score: 7.3 bits;  conditional E-value: 0.0032
                 SEEEEEEETTSSEEE.EEETTSEE CS
        WD40  12 svtslafspdgawla.sGsdDgtv 34 
                 +v+++afsp+g+ la  ++ D +v
  EEA20837.1 207 WVHGVAFSPSGNALAfVSH-DSSV 229
                 59***********975677.9887 PP

  == domain 6  score: 4.6 bits;  conditional E-value: 0.022
                 EEEEEETTSSEEEEEETTSEE CS
        WD40  14 tslafspdgawlasGsdDgtv 34 
                 tsl +s + + +a+G+ D+ v
  EEA20837.1 255 TSLVWSGEDQIIAAGH-DCEV 274
                 8999***********9.9977 PP

  == domain 7  score: 3.5 bits;  conditional E-value: 0.049
                 EEEEETTSEEEEE CS
        WD40  25 lasGsdDgtvriW 37 
                 +++++ Dg v +W
  EEA20837.1 348 FTTSGVDGRVVVW 360
                 456777******* PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.0     0.037   1.1e+02      44      72 ..      17      44 ..      10      77 .. 0.71
   2 !   16.7   0.0   2.3e-06    0.0069       2      68 ..     105     174 ..     104     181 .. 0.84
   3 !    6.5   0.0    0.0033       9.9      23      64 ..     190     231 ..     183     236 .. 0.82
   4 ?    2.5   0.0     0.059   1.8e+02      42      70 ..     255     283 ..     247     296 .. 0.79

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.037
  ANAPC4_WD40 44 LaWkpdgklLavaysdgevrlldaesgkv 72
                  ++++d + Lava  d++v+l++a+  k 
   EEA20837.1 17 HSFSQDKSTLAVAR-DNNVELYQASGNKF 44
                 56778888888874.66788888776654 PP

  == domain 2  score: 16.7 bits;  conditional E-value: 2.3e-06
  ANAPC4_WD40   2 swcptmDLiAlatedgellvfRlngqrvwtl...eedkedsevrsLaWkpdgklLavaysdgevrlldae 68 
                  +w+p+   +A+++    ++v+ ++ ++ w +    ++   s+++ LaW+p+  lLa +  d++ r+++++
   EEA20837.1 105 RWSPSEQKFAVGSGARVIAVCYFEEENDWWIskhLKKPIRSTITTLAWHPNSVLLAAGSTDSHARVFSSY 174
                  68899999999999999999999888888775554555678999***********************998 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.0033
  ANAPC4_WD40  23 RlngqrvwtleedkedsevrsLaWkpdgklLavaysdgevrl 64 
                  Rl ++ v +   +++ + v+++a++p+g+ La++ +d++v +
   EEA20837.1 190 RLPFNTVCGEYLNDTAGWVHGVAFSPSGNALAFVSHDSSVTV 231
                  6666666666667778889******************99976 PP

  == domain 4  score: 2.5 bits;  conditional E-value: 0.059
  ANAPC4_WD40  42 rsLaWkpdgklLavaysdgevrlldaesg 70 
                  +sL W+ +++++a +++    rl   e+g
   EEA20837.1 255 TSLVWSGEDQIIAAGHDCEVYRLQGDENG 283
                  89************998766666665555 PP

>> Gmad1  Lipoprotein LpqB beta-propeller domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.1     0.059   1.8e+02      71     138 ..      18      78 ..       7     126 .. 0.56
   2 ?   -1.2   0.1      0.47   1.4e+03      65      88 ..     145     168 ..      93     180 .. 0.64
   3 !   15.2   0.1   4.6e-06     0.014      21      97 ..     204     283 ..     195     340 .. 0.77

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.059
       Gmad1  71 SwdrdgalWvvedgaevvravrddaegevavveVdasalragpvtelrvSrDGtRaAvivekdgggkv 138
                 S+++d++  +v ++++v+  ++   +g+    + + ++  +++vt + +++D  R++  +   ++++ 
  EEA20837.1  18 SFSQDKSTLAVARDNNVELYQA---SGNKFTLKDELKGH-DKTVTGVDIAPDSGRIVTCS---QDRNA 78 
                 5555544444444444444444...33333333333332.36777777777777776666...33444 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.47
       Gmad1  65 gsltrpSwdrdgalWvvedgaevv 88 
                 +++t + w +++ l ++  ++ ++
  EEA20837.1 145 STITTLAWHPNSVLLAAGSTDSHA 168
                 245555555555555555544444 PP

  == domain 3  score: 15.2 bits;  conditional E-value: 4.6e-06
       Gmad1  21 gavdlrsaAvSrdgqqvaavtapdggrtLvvgsyggeasevl..egg..sltrpSwdrdgalWvvedgaevvravrddaeg 97 
                 +a  ++ +A S++g+ +a+v+++++ + ++  ++++ ++ +l  + +   +t++ w++++++ ++  + ev r++  d++g
  EEA20837.1 204 TAGWVHGVAFSPSGNALAFVSHDSSVTVVYPSAPDQPPKAMLniSTRllPFTSLVWSGEDQIIAAGHDCEVYRLQG-DENG 283
                 55567899*************9999999999***********653336799*************999999999987.4444 PP

>> DUF3642  Bacterial lipoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.0   0.00068         2      45      77 ..      19      53 ..      10      59 .. 0.75
   2 ?    2.8   0.0     0.048   1.4e+02      48      67 ..     262     281 ..     255     283 .. 0.90

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00068
     DUF3642 45 ldadnklilvGdd..vktyklvgnqltvddfdrdq 77
                +  d+ ++ v  d  v+ y+  gn++t++d ++  
  EEA20837.1 19 FSQDKSTLAVARDnnVELYQASGNKFTLKDELKGH 53
                5567777777766679***************9765 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.048
     DUF3642  48 dnklilvGddvktyklvgnq 67 
                 ++++i  G d ++y+l+g++
  EEA20837.1 262 EDQIIAAGHDCEVYRLQGDE 281
                 89**************9976 PP

>> DPPIV_N  Dipeptidyl peptidase IV (DPP IV) N-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.0      0.02        59      35      68 ..       6      37 ..       1      61 [. 0.77
   2 ?    0.8   0.1     0.055   1.6e+02      42      59 ..      98     115 ..      66     149 .. 0.74
   3 ?    5.4   0.0    0.0022       6.5     105     128 ..     210     233 ..     203     244 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.02
                CEEEETTTT.BSEEEEESSTTEEEEEETTEEEEE CS
     DPPIV_N 35 veelspgeeklqlakwSPagdklafvrnnnLyvr 68
                v++l ++  ++++  +S ++  la+ r+nn+ + 
  EEA20837.1  6 VHHLFHS--PIADHSFSQDKSTLAVARDNNVELY 37
                4555555..999******************7555 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.055
                 TT.BSEEEEESSTTEEEE CS
     DPPIV_N  42 eeklqlakwSPagdklaf 59 
                 ++++++++wSP  +k+a+
  EEA20837.1  98 NRAATYVRWSPSEQKFAV 115
                 677788888888887775 PP

  == domain 3  score: 5.4 bits;  conditional E-value: 0.0022
                 EEEE-TTSSEEEEEEEECTTS-EE CS
     DPPIV_N 105 avwWspdgsrlaylrfdeseVpei 128
                 +v++sp+g++la+++ d+s +  +
  EEA20837.1 210 GVAFSPSGNALAFVSHDSSVTVVY 233
                 899************999865544 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0     0.011        32     187     216 ..      11      39 ..       5     104 .. 0.91
   2 ?    0.2   0.0     0.099   2.9e+02     187     221 ..     144     178 ..     124     186 .. 0.85
   3 ?    3.2   0.0     0.012        35     189     212 ..     207     230 ..     198     241 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.011
    Ge1_WD40 187 hsliveaafspdGtalatasedGevkffqv 216
                 hs i + +fs d  +la+a  d  v ++q 
  EEA20837.1  11 HSPIADHSFSQDKSTLAVA-RDNNVELYQA 39 
                 6789999**********98.6889999995 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.099
    Ge1_WD40 187 hsliveaafspdGtalatasedGevkffqvylede 221
                  s+i++ a+ p+   la+ s+d   + f  y+++ 
  EEA20837.1 144 RSTITTLAWHPNSVLLAAGSTDSHARVFSSYIKGI 178
                 5789999999******************9999865 PP

  == domain 3  score: 3.2 bits;  conditional E-value: 0.012
    Ge1_WD40 189 liveaafspdGtalatasedGevk 212
                  +   afsp G ala  s+d  v 
  EEA20837.1 207 WVHGVAFSPSGNALAFVSHDSSVT 230
                 577889**************9885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (362 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       338  (0.0188521); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.56u 0.24s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2456.28
//
Query:       EEA20838.1  [L=415]
Description: extracellular triacylglycerol lipase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.2e-30  104.5   0.0    6.7e-30  103.8   0.0    1.3  1  Lipase_3       Lipase (class 3)
    0.00016   21.1   0.0    0.00033   20.0   0.0    1.5  1  Hydrolase_4    Serine aminopeptidase, S33
    0.00068   20.3   0.0     0.0011   19.6   0.0    1.4  1  Abhydrolase_6  Alpha/beta hydrolase family
     0.0044   16.6   0.2        0.1   12.2   0.0    2.7  3  DUF2974        Protein of unknown function (DUF2974)
  ------ inclusion threshold ------
      0.012   15.2   0.0      0.021   14.5   0.0    1.3  1  Abhydrolase_1  alpha/beta hydrolase fold
      0.013   15.3   0.0      0.024   14.4   0.0    1.4  1  PGAP1          PGAP1-like protein
      0.015   15.4   0.0      0.038   14.1   0.0    1.6  1  Thioesterase   Thioesterase domain
      0.051   13.1   0.0      0.099   12.1   0.0    1.5  1  DUF676         Putative serine esterase (DUF676)
      0.068   13.1   0.0       0.22   11.4   0.0    1.8  2  Cutinase       Cutinase
       0.11   12.1   0.0        0.2   11.3   0.0    1.3  1  Abhydrolase_8  Alpha/beta hydrolase
       0.26   11.7   0.8       0.51   10.7   0.1    1.8  2  DrsE           DsrE/DsrF-like family


Domain annotation for each model (and alignments):
>> Lipase_3  Lipase (class 3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.8   0.0   4.1e-33   6.7e-30       1     140 [.     122     284 ..     122     286 .. 0.93

  Alignments for each domain:
  == domain 1  score: 103.8 bits;  conditional E-value: 4.1e-33
                 EEEE----------------EEE-HHHH-G..................TT-EEEHHHHHHHHS-HHHHHHHHHHHHHHHTT-EEEEEEEETHHHHHHHH CS
    Lipase_3   1 vvafRGtesakdwltdldfslteakellek..................eggkvhsgfleayeeslreqvlkelkrllekypeysivvtGHSLGgalAlL 81 
                 +vafRGt s ++++ dl + ++ + + +++                  ++++vh gf+++++ + r +vl+ + + lekyp+y++++ GHSLGga+A+L
  EEA20838.1 122 IVAFRGTYSLTNTIIDLSAVPQTYVPYPTDgdddgnnnkpsviepkqcQNCTVHAGFWTSWK-NSRGTVLSAVTQALEKYPDYEVTLIGHSLGGAVAAL 219
                 69*******************999999888999*****************************.************************************ PP

                 HHHHHHHTT-SS---EEEEEES----B-HHHHHHHH........T-TTE.....EEEEEEETT--GGG-S-S CS
    Lipase_3  82 aaldlvengenekkkvtvvtfGqPrvgnkefaklvd........sqlnk.....kvlrvvntnDivPrlppl 140
                 a+l++ ++g     ++ v tfG+P+vgn ++a++++        +   +     ++ r+++ nD++P lp  
  EEA20838.1 220 ASLEMYSRG----LDPHVTTFGEPKVGNDKMADFISeifdlskgK---EddtqmRYRRITHVNDPIPLLPLT 284
                 *********....78*********************777775540...25566699*************975 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   0.0     2e-07   0.00033      48      95 ..     175     223 ..     168     235 .. 0.87

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 2e-07
  Hydrolase_4  48 krghvpsfddyvdDlaafvekvkeehpelplfllGhSmGGliallyl.l 95 
                  + g ++s++     + ++v+++ e++p+ +++l+GhS+GG++a+l+  +
   EEA20838.1 175 HAGFWTSWKNSRGTVLSAVTQALEKYPDYEVTLIGHSLGGAVAALASlE 223
                  67889999999999999**************************998744 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.0   6.8e-07    0.0011      44     125 ..     179     267 ..     140     333 .. 0.66

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 6.8e-07
                    S--HHH.....CHHHHHHHCCTT..TTSEEEEEETCHHHHHHHHHHCC...........EEEEES-..----TTTS----TTHHHHHHTT-CCCCH CS
  Abhydrolase_6  44 pldled.....ladlaalldelaagggpvvlvGHSlGGalalaaapla.........lvvgvlldppptalpagllaaalelllallallrllawl 125
                    ++++ +     l ++ ++l++ +  + +v l+GHSlGGa+a++   +          ++v+ + +p   ++ + +++++ e+++   + + + +++
     EEA20838.1 179 WTSWKNsrgtvLSAVTQALEKYP--DYEVTLIGHSLGGAVAAL---ASlemysrgldPHVTTFGEP--KVGNDKMADFISEIFDLSKGKEDDTQMR 267
                    45666644343344555666665..8999**********9999...44444567777777788888..5555555555555555443333333333 PP

>> DUF2974  Protein of unknown function (DUF2974)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0      0.19   3.2e+02      35      47 ..     117     129 ..     106     137 .. 0.76
   2 !   12.2   0.0   6.2e-05       0.1      74     106 ..     192     226 ..     179     238 .. 0.80
   3 ?   -2.1   0.0       1.4   2.3e+03     139     173 ..     327     361 ..     321     370 .. 0.80

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.19
     DUF2974  35 eedtlvvaFRGTd 47 
                 +++ ++vaFRGT 
  EEA20838.1 117 SAKRIIVAFRGTY 129
                 578899******4 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 6.2e-05
     DUF2974  74 Ylnkileesegk.iylgGhSkGGnlAvyaamn.ae 106
                  ++++le++++  ++l GhS GG +A++a+++  +
  EEA20838.1 192 AVTQALEKYPDYeVTLIGHSLGGAVAALASLEmYS 226
                 5789999999966****************998344 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 1.4
     DUF2974 139 skikklvPessivgmlleseeeviivksdakgilq 173
                 ++ +++v + s+++m +  + e i ++s+ ++  q
  EEA20838.1 327 DREEETVKNLSLLAMSMVPQRENILLSSSDNQQQQ 361
                 56678899999999999999999999988877666 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.0   1.3e-05     0.021      58      91 ..     188     221 ..     152     231 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 1.3e-05
                    HHHHHHHHHHHHCTTSSEEEEEETHHHHHHHHHH CS
  Abhydrolase_1  58 svaddldrildalgddkltlvGhSmGGmialaya 91 
                    +v   + ++l++++d ++tl+GhS+GG++a+ + 
     EEA20838.1 188 TVLSAVTQALEKYPDYEVTLIGHSLGGAVAALAS 221
                    577788999********************99765 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   1.5e-05     0.024      89     114 ..     201     225 ..     187     260 .. 0.75

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.5e-05
       PGAP1  89 eptsviliGHSmGGivaraaltlkny 114
                 +  +v liGHS+GG va a++ l+ y
  EEA20838.1 201 PDYEVTLIGHSLGGAVA-ALASLEMY 225
                 6678*************.45555555 PP

>> Thioesterase  Thioesterase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   2.3e-05     0.038      49      95 ..     187     232 ..     176     237 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 2.3e-05
                   HHHHHHHHHHHHHH-SSSSEEEEEETHHHHHHHHHHHHHHHCT-SEE CS
  Thioesterase  49 eelaaeyaealrqiqpegPyalfGhSlGgllAfevArqLesqGlavk 95 
                   +++ + +++al++  +   ++l+GhSlGg++A  ++ ++ s+Gl ++
    EEA20838.1 187 GTVLSAVTQALEKYPDY-EVTLIGHSLGGAVAALASLEMYSRGLDPH 232
                   56667777777776655.899******************99999886 PP

>> DUF676  Putative serine esterase (DUF676)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   6.1e-05     0.099      45     103 ..     167     227 ..     120     251 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 6.1e-05
      DUF676  45 sennesktfkgidvlgerlaeevlevvkkkkdk..nkkiSfvghSlGgliaraaiaklkek 103
                 ++ +++  ++g+ +  ++    vl+ v ++ +k  +  + ++ghSlGg +a  a   ++++
  EEA20838.1 167 KQCQNCTVHAGFWTSWKNSRGTVLSAVTQALEKypDYEVTLIGHSLGGAVAALASLEMYSR 227
                 55555666666655555444444444444444444448*************9998877754 PP

>> Cutinase  Cutinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       1.9   3.2e+03     115     139 ..      24      48 ..      21      58 .. 0.78
   2 ?   11.4   0.0   0.00014      0.22      61      99 ..     185     223 ..     170     266 .. 0.80

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 1.9
                 EEEEES-TTCCCCTTS-TTS-GGGE CS
    Cutinase 115 avvlfGdpsnvaglpevsklyaski 139
                 a+v+ Gd++nv + ++ ++  ++++
  EEA20838.1  24 AAVVHGDAQNVLQKQQNQEDITDRT 48 
                 8899999999777777666666666 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00014
                 HHHHHHHHHHHHHHH-TT-EEEEEEETHHHHHHHHHHTT CS
    Cutinase  61 gakeaaalvqslaskCPdtkivlgGYSqGaqvidnaieg 99 
                    ++ ++v+++ +k Pd ++ l G S G++v++ a  +
  EEA20838.1 185 SRGTVLSAVTQALEKYPDYEVTLIGHSLGGAVAALASLE 223
                 55678899************************9988666 PP

>> Abhydrolase_8  Alpha/beta hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00012       0.2      94     129 ..     190     223 ..     173     260 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00012
  Abhydrolase_8  94 LnallrdlratsvpgqhlallgHSYGSlvaslAldd 129
                    L+a  ++l++   p+ +++l+gHS G  va+lA  +
     EEA20838.1 190 LSAVTQALEKY--PDYEVTLIGHSLGGAVAALASLE 223
                    77777777654..7******************9654 PP

>> DrsE  DsrE/DsrF-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.1   0.00031      0.51      35      79 ..      24      71 ..      10      77 .. 0.76
   2 ?   -3.1   0.0         6   9.7e+03      74      90 ..     309     325 ..     306     342 .. 0.67

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00031
                EEEE-GGGGGGGBS---TGGGTS---.GGGGGGCGG.GT.-EEEEEHH CS
        DrsE 35 svffygdGvllllkgqtanpadeknl.aellkalke.yg.vklyvCgq 79
                + +++gd+ ++l+k+q++++++++ +  +l+++l+e ++ +++  C+ 
  EEA20838.1 24 AAVVHGDAQNVLQKQQNQEDITDRTVsEALFAELEEsARlADIAYCVG 71
                4799**********************5557899999777888888865 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 6
                 EEEEHHHHHHTT--GGG CS
        DrsE  74 lyvCgqaakargldede 90 
                 +  C+  a++r ++++e
  EEA20838.1 309 VEHCVGNADKRCISSSE 325
                 66799999999999655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (415 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       980  (0.05466); expected 358.6 (0.02)
Passed bias filter:                      723  (0.0403257); expected 358.6 (0.02)
Passed Vit filter:                        69  (0.00384851); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.61u 0.29s 00:00:00.89 Elapsed: 00:00:00.47
# Mc/sec: 2658.80
//
Query:       EEA20839.1  [L=1198]
Description: WW domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.6e-11   43.0   0.4    7.5e-11   41.9   0.4    1.6  1  WW        WW domain
  ------ inclusion threshold ------
      0.053   12.5   0.3       0.12   11.4   0.3    1.5  1  PhoD      PhoD-like phosphatase


Domain annotation for each model (and alignments):
>> WW  WW domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.9   0.4   8.4e-15   7.5e-11       1      31 []     475     505 ..     475     505 .. 0.98

  Alignments for each domain:
  == domain 1  score: 41.9 bits;  conditional E-value: 8.4e-15
                 X-TTEEEEE-TTTT-EEEEETTT--EESS-- CS
          WW   1 LPpGWeeqwdpdsGrvYYyNheTgetqWekP 31 
                 LP+GW+++ d++sG++YY++  T+ tqWe P
  EEA20839.1 475 LPEGWIAHLDSNSGQYYYIHLPTQSTQWEFP 505
                 8****************************98 PP

>> PhoD  PhoD-like phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.3   1.3e-05      0.12      57     100 ..     775     818 ..     758     837 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 1.3e-05
        PhoD  57 ppkeivtladYReryaqyktdadlqaahaaapfivvwDDHEvaN 100
                 p++e +  + Y   y+ +   ++l++a a++p i ++DDH + +
  EEA20839.1 775 PAHEDEVSHAYFHFYTSHFDQPHLREAFAQIPYILQLDDHDIFD 818
                 3366677778889999999*********************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1198 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       555  (0.0309554); expected 358.6 (0.02)
Passed bias filter:                      316  (0.0176251); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.90u 0.30s 00:00:01.20 Elapsed: 00:00:00.51
# Mc/sec: 7091.87
//
Query:       EEA20840.1  [L=710]
Description: hypothetical protein PMAA_046590 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      3e-17   62.5   4.7    4.3e-17   62.0   4.7    1.2  1  Fungal_trans_2  Fungal specific transcription factor domain
      5e-10   39.3   7.0    8.8e-10   38.5   7.0    1.3  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.0   4.7   4.8e-21   4.3e-17      12     381 ..     306     705 ..     285     708 .. 0.77

  Alignments for each domain:
  == domain 1  score: 62.0 bits;  conditional E-value: 4.8e-21
  Fungal_trans_2  12 pllspvpessnpfrkvllplalsnkallhallalsafhlqskgpkdslereakrykslalkelqealaelsstlsrnekykdiLaaiLllcsiei 106
                     +l+sp +++  p  +++  la + ++l+ha++a+sa+ l+ ++ ++  + +a++++++a   lq al++ +   s     + ++ +  ll ++e+
      EEA20840.1 306 DLFSPLSSPIIPGVEIFEDLASTFQPLYHAIMAVSALSLARQHRSK--SIDALQHYQQAFPSLQIALRDTNDLCS-----DGLFLTHFLLLVYEV 393
                     488899999999999************************8888777..99*************************.....**************8 PP

  Fungal_trans_2 107 ssgdvsd...wrvhLeaatsliksrggskasssslsskarfllrifayldilssttlg.......rgpsfpseeyekllenkkeesdsg...... 185
                     +  ++     w  h+   t +  +r  +    s +++ + +l+ ++    +ls   +g       ++ ++ps+ ++                   
      EEA20840.1 394 AAAEEAGsnlWSHHMARLTQISLMRISQ--FGSEQYPYIVWLVCNIDLYALLSGAGTGeflktmlDNNLLPSSGSQLY----------Pvapsgh 476
                     8888444456999999999999999998..445556666666666666666666555555555553333333333222..........0333333 PP

  Fungal_trans_2 186 ..........ldplmGcsnslilliseisrLarekrsarkd.......seleplsileeaseleqrll.swkprssdlepdldeterasslskdl 262
                               l +++ ++++ + l s+++ La+++r+++++       s +   + +++++e+    +  w  ++ ++  + + +  +++ +   
      EEA20840.1 477 sviypeehetLPSVLHFNHETFVLASRLAFLAADLRHQSDEyhtgsppSPNRAFDPKRRLYEIRDSFHrLWDCPQ-AHYLCENMKTLPQRSR--- 567
                     3344555555888********************************999999999999999999999996776664.4555555555554444... PP

  Fungal_trans_2 263 telfrlaaliylyrlvlglpps............spevqelvkkllellellpsspv.aiasLlWplFiaGceavdeddRdfvrrrleeleqsrl 344
                      e+ ++a+ +y  +++ + ++             ++ +   +++++ + e++  s+    + +++plFiaG++ ++  ++++  +++ ++e++++
      EEA20840.1 568 -EVLQNALSLYHSCMLFSYTSVwngqllgpegasDEILAHHTNNIFHIAESIVHSNQfDLRFIIFPLFIAGVSTSSTGQKMMAMDFICSMEKQGI 661
                     .5666666666656663333333333445556668899999************8777799*****************999999********9999 PP

  Fungal_trans_2 345 .gnvrrarqvleevWrrrddgee.......kidWrdvmekkgwel 381
                      +n++++r++l+ v +++ + +        ++ W dvm++ g+ +
      EEA20840.1 662 gRNATTTRHLLQMVYQAQTE-QLmtighsaNVGWSDVMVQQGIQI 705
                     9*****************94.335666666999*****9888766 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.5   7.0   9.9e-14   8.8e-10       1      35 [.      63      96 ..      63     100 .. 0.92

  Alignments for each domain:
  == domain 1  score: 38.5 bits;  conditional E-value: 9.9e-14
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCT CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfyse 35
                ++C++Cr++KvKCd+++P+C++C++l+  C  ys 
  EEA20840.1 63 TGCWTCRSRKVKCDERRPSCGQCARLGHGCD-YSP 96
                58****************************9.765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (710 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       415  (0.0231469); expected 358.6 (0.02)
Passed bias filter:                      330  (0.0184059); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.27s 00:00:00.94 Elapsed: 00:00:00.48
# Mc/sec: 4469.32
//
Query:       EEA20841.1  [L=1857]
Description: proteasome component (Ecm29), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   2.9e-159  530.9   3.0   5.3e-157  523.5   0.0    3.5  4  Ecm29          Proteasome stabiliser
    0.00074   19.6   1.4        3.2    8.3   0.1    7.2  8  HEAT           HEAT repeat
     0.0014   19.1   0.2        2.8    8.6   0.1    4.6  4  Vac14_Fab1_bd  Vacuolar 14 Fab1-binding region
     0.0043   17.5   6.1         16    6.2   0.0    7.7  8  HEAT_EZ        HEAT-like repeat


Domain annotation for each model (and alignments):
>> Ecm29  Proteasome stabiliser
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  523.5   0.0  1.2e-160  5.3e-157       1     497 []      18     535 ..      18     535 .. 0.96
   2 ?   -0.4   0.1     0.077   3.5e+02     291     396 ..     731     834 ..     719     974 .. 0.63
   3 !    5.3   0.1    0.0014       6.4     316     428 ..    1223    1331 ..    1190    1334 .. 0.81
   4 ?   -2.6   0.0      0.36   1.6e+03     230     247 ..    1484    1514 ..    1356    1521 .. 0.59

  Alignments for each domain:
  == domain 1  score: 523.5 bits;  conditional E-value: 1.2e-160
       Ecm29   1 vekvelRlalAdtdekLeklLskfLpplLlklasphasvRkkVieilqhinkriksrpsikLPveaLlkqyketeasslvrnfsllyiekgidRlsaee 99 
                 v+kvelR+alAd+dekL+klL+++L+plLlklas+h +vR+kVi ++qhin rik ++si+LPv+aLlkq+ke+ +s+l+r+f+l+yi++gidRl+a+ 
  EEA20841.1  18 VSKVELRIALADSDEKLQKLLQTYLAPLLLKLASEHLAVRNKVIAVCQHINLRIK-PQSIQLPVTALLKQFKEQ-SSQLIRHFDLIYIQQGIDRLDASA 114
                 78*****************************************************.*****************9.999********************* PP

       Ecm29 100 rkellpkllkgis..kkpsqhqarlfnlllklLgklklpprgskedealkellglsdkpedakflleffldflllspskssesstscpGlsaaevkflt 196
                 r+ellp +l+gi+  +  s++ a++fnl+l+lL+ l+lpp++s ed++l e+l+ls+  +d++ l+ +++++llls++++   + +cpGls++e++fl+
  EEA20841.1 115 RVELLPAALQGIAqlDVASAQTASVFNLILRLLPLLRLPPKDSPEDQKLGEKLSLSE--ADTRSLAVWLGKLLLLSQAAK--DARTCPGLSPSEYTFLN 209
                 *************88888999***********************************5..****************75433..4558************* PP

       Ecm29 197 kkak......vsalkkeeleetKlailkflasgaftdeerevlpallvasadsdssvsdraeelLKrlsvdledealvdkLfslflgskeeskispasp 289
                 k+a+      +s++ + +l+etK  ++kflasgaf+++ r +lpa++ + ads+s++sd+++++LKr+++dled+++v++L++l++g++ ++ + pa+ 
  EEA20841.1 210 KSASfeetwnPSTQGGLNLTETKYFVAKFLASGAFNNSAR-FLPAIILS-ADSNSRLSDIGDDILKRFNPDLEDAEVVEQLYKLYFGTTGSDAALPARI 306
                 9999******9999*********************99998.*****888.************************************************* PP

       Ecm29 290 alrlkIlslLskSvlaaansfpaniqvife.sly......gsglessKLrslllqFinwvarhgsskelkkiapvllsglrklidsqgwpep....ekn 377
                 +l++kIls+L kSv+a++  ++ +i+++ + +l+      ++gl++sK+rs+++ Fi+wv+r+g  ++l+ iap+ + glr++++sqgwp+p    ++ 
  EEA20841.1 307 PLQVKILSFLGKSVKATT--YTGEISKLLDeGLFstiaksAQGLQASKIRSQIFMFITWVVRMGAPSDLRIIAPNAVIGLRQFVESQGWPDPgvsgQRL 403
                 **************9999..9*********9999**************************************************************999 PP

       Ecm29 378 ssaseelrslaYealGlLakrapslvred...lsliefLFdsLeeee..sevrvsIqeALssllsafkeleseaskekLeellleylead.......ee 464
                 s++++ lr+laYe++G L  +  s  + d   ++l+++LF+sL++++  +e+ vsI++AL s+l++ +++ +e ++++L ++l  +++++       + 
  EEA20841.1 404 SQTDIGLRGLAYESIGVLSPKISSGGSVDyidMDLLRWLFSSLASDAsaAEIYVSIEQALGSILNCCTGNLPEGVQSELGNFLEFQMQSQpgtesslTG 502
                 9******************7777664444444***************877*******************99****************999*******99 PP

       Ecm29 465 esaersvryvavkyanalfpfsdveaRyililA 497
                    +rs++y av+yan+++p+ d +aR+i++lA
  EEA20841.1 503 YPIVRSTHYTAVRYANRCLPYWDLTARWIDLLA 535
                 9*******************************8 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.077
       Ecm29 291 lrlkIlslLskSvlaaansfpaniqvifesly........gsglessKLrslllqFinwvarhgsske............................lkk 353
                 + ++I+ +L   + + +   +++ q++f++l+        ++g  ++K+r ++l     + r +++k                                
  EEA20841.1 731 IAARIFGILASHT-SVT---ESDCQQVFSDLLntsigwkgAIGEAANKVRGAILAVAYLLSRLAYRKRlnvipeaqigqyitlavevldqsrdsqlS-- 823
                 5567777777666.444...46667777766667777777666444488888888888888888877733333333333333333333333333330.. PP

       Ecm29 354 iapvllsglrklidsqgwpepeknssaseelrslaYealGlLa 396
                                                 +    ++G+La
  EEA20841.1 824 --------------------------------EAVQVTIGQLA 834
                 ................................33333333333 PP

  == domain 3  score: 5.3 bits;  conditional E-value: 0.0014
       Ecm29  316 vifeslygsgless.KLrslllqFinwvarhgsskelkkiapvllsglrklidsqgwpepeknssaseelrslaYealGlLakrapslvred..lsl 409 
                  ++++++++s  +++ +L +++ + + +++++g+++   k a+ +l ++  ++  q+  e     s+++e++++a ++l +++k++ps   +    ++
  EEA20841.1 1223 KVMDDIKESVRTAAlRLCQVITNILIRTLEVGDTDS--KRAKTMLGHIIPFLLGQDGME-----SSAQEVQGYAISTLVQIIKKSPSALLRPfmAQI 1312
                  566777777777779*****************9554..677777778888887444333.....35689******************9988866799 PP

       Ecm29  410 iefLFdsLeeeesevrvsI 428 
                  +e++++sL++ e++ + +I
  EEA20841.1 1313 LEKFLSSLSSLEPQAVNYI 1331
                  ********99888777666 PP

  == domain 4  score: -2.6 bits;  conditional E-value: 0.36
       Ecm29  230 r.............evlpallvasadsdssv 247 
                  +              +lp+++va+ d+d++ 
  EEA20841.1 1484 MsklssdrfsnfstAALPFVFVAKQDTDEQT 1514
                  0333333333333367888888888887765 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1      0.93   4.2e+03       2      23 ..      43      63 ..      42      67 .. 0.78
   2 ?   -2.0   0.0       1.4   6.2e+03       3      30 ..     714     742 ..     714     743 .. 0.85
   3 ?   -2.4   0.0         2   8.8e+03      18      28 ..     866     876 ..     865     878 .. 0.86
   4 !    8.3   0.1   0.00072       3.2      12      30 ..    1186    1204 ..    1173    1205 .. 0.82
   5 ?   -1.0   0.0      0.69   3.1e+03      15      28 ..    1231    1244 ..    1226    1247 .. 0.83
   6 ?   -0.7   0.0      0.54   2.4e+03       8      29 ..    1277    1298 ..    1268    1300 .. 0.78
   7 ?    0.7   0.0      0.19   8.5e+02       5      25 ..    1543    1563 ..    1540    1569 .. 0.82
   8 ?   -2.4   0.0         2   8.8e+03       3      30 ..    1583    1610 ..    1582    1611 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.93
                HHHHHHHHT-SSHHHHHHHHHH CS
        HEAT  2 lPlllkllsDpspeVReaAaka 23
                 Plllk l +++  VR  ++  
  EEA20841.1 43 APLLLK-LASEHLAVRNKVIAV 63
                599***.689999999877765 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.4
                 HHHHHHHT-SSHHH.HHHHHHHHHHHHHC CS
        HEAT   3 PlllkllsDpspeV.ReaAakaLgalaev 30 
                 P +l+ + +++ +V  + Aa+ +g la++
  EEA20841.1 714 PSILQRIYSTNDHVlQRIAARIFGILASH 742
                 6788888899999889999*999999987 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 2
                 HHHHHHHHHHH CS
        HEAT  18 eaAakaLgala 28 
                 e+A+ aLg+l+
  EEA20841.1 866 ENAIHALGQLS 876
                 79*******96 PP

  == domain 4  score: 8.3 bits;  conditional E-value: 0.00072
                  SSHHHHHHHHHHHHHHHHC CS
        HEAT   12 pspeVReaAakaLgalaev 30  
                   +++VR+a++ a+++l+++
  EEA20841.1 1186 REWRVRQASCAAIADLLQG 1204
                  58**************986 PP

  == domain 5  score: -1.0 bits;  conditional E-value: 0.69
                  HHHHHHHHHHHHHH CS
        HEAT   15 eVReaAakaLgala 28  
                  +VR aA++ +  + 
  EEA20841.1 1231 SVRTAALRLCQVIT 1244
                  7******9998876 PP

  == domain 6  score: -0.7 bits;  conditional E-value: 0.54
                  HHT-SSHHHHHHHHHHHHHHHH CS
        HEAT    8 llsDpspeVReaAakaLgalae 29  
                   +++++ eV   A+ +L+++++
  EEA20841.1 1277 GMESSAQEVQGYAISTLVQIIK 1298
                  46789999999********998 PP

  == domain 7  score: 0.7 bits;  conditional E-value: 0.19
                  HHHHHT-SSHHHHHHHHHHHH CS
        HEAT    5 llkllsDpspeVReaAakaLg 25  
                  + + l+++++ +  +A++a +
  EEA20841.1 1543 ISERLESSNWTIKHSACLATA 1563
                  567899***********9865 PP

  == domain 8  score: -2.4 bits;  conditional E-value: 2
                  HHHHHHHT-SSHHHHHHHHHHHHHHHHC CS
        HEAT    3 PlllkllsDpspeVReaAakaLgalaev 30  
                  P+l k  + + ++  e ++ka+++++e+
  EEA20841.1 1583 PILEKSVNGKTWDGKEKVLKAFVKFVEN 1610
                  77788888888999999******99986 PP

>> Vac14_Fab1_bd  Vacuolar 14 Fab1-binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.6   0.1   0.00062       2.8      19      92 ..    1169    1240 ..    1158    1245 .. 0.75
   2 ?    4.0   0.0     0.017        78      20      74 ..    1260    1317 ..    1250    1330 .. 0.79
   3 ?   -2.5   0.0       1.8     8e+03      42      81 ..    1472    1511 ..    1452    1517 .. 0.56
   4 ?   -0.9   0.0      0.58   2.6e+03       4      34 ..    1556    1586 ..    1553    1590 .. 0.87

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00062
  Vac14_Fab1_bd   19 kkikeyleeivkpvlkcfsDkdsrvRyyacEslyniakvak.gevlkllneifdalvklvaDsdesvksgaelld 92  
                     ++ ++++++++++++     ++ rvR  +c ++  + +    ++  k+lnei++  +k++ D +esv+++a  l 
     EEA20841.1 1169 TQFDPIMDDLLSSII---AGREWRVRQASCAAIADLLQGRSiEKYDKYLNEILSKAFKVMDDIKESVRTAALRLC 1240
                     444455555555544...568899999999999888775441556679**********************97765 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.017
  Vac14_Fab1_bd   20 kikeyleeivkpvl..kcfsDkdsrvRyyacEslyniakvakgevlk.llneifdalv 74  
                     ++k++l +i++ +l  + ++ + ++v  ya+ +l  i+k++ +++l+ ++ +i++ + 
     EEA20841.1 1260 RAKTMLGHIIPFLLgqDGMESSAQEVQGYAISTLVQIIKKSPSALLRpFMAQILEKFL 1317
                     477788888888884446889999**********************856677877654 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 1.8
  Vac14_Fab1_bd   42 rvRyyacEslyniakvakgevlkllneifdalvklvaDsd 81  
                       R  a E l+ ++k + +++ ++ +  +  ++    D+d
     EEA20841.1 1472 SQRTVAGEILHSMSKLSSDRFSNFSTAALPFVFVAKQDTD 1511
                     5555566666666665555554444444444444444444 PP

  == domain 4  score: -0.9 bits;  conditional E-value: 0.58
  Vac14_Fab1_bd    4 kggligLaavaialekkikeyleeivkpvlk 34  
                     + + ++ a v  +l+k++++ + eiv p+l+
     EEA20841.1 1556 HSACLATADVVTSLGKSLDQSTAEIVWPILE 1586
                     567788899999*****************97 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.2      0.16     7e+02      16      48 ..      29      60 ..      23      65 .. 0.63
   2 ?   -2.5   0.0       1.8   7.9e+03      45      55 .]     865     875 ..     859     875 .. 0.86
   3 ?    1.4   0.2       0.1   4.7e+02       5      47 ..     969    1012 ..     964    1019 .. 0.59
   4 !    6.2   0.0    0.0035        16       1      52 [.    1188    1240 ..    1188    1243 .. 0.63
   5 ?    0.3   0.0      0.24   1.1e+03      29      54 ..    1268    1295 ..    1257    1296 .. 0.84
   6 ?   -1.0   0.0      0.59   2.6e+03      14      39 ..    1297    1322 ..    1288    1327 .. 0.75
   7 ?   -1.5   0.0      0.89     4e+03      17      50 ..    1527    1560 ..    1526    1561 .. 0.86
   8 ?    0.8   0.0      0.17   7.5e+02       3      45 ..    1640    1682 ..    1638    1684 .. 0.62

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.16
     HEAT_EZ 16 ggepellqplvpeilpaLlalLnddsdeVRaaA 48
                     l+++l++ + p+Ll+l  +++ +VR ++
  EEA20841.1 29 DSDEKLQKLLQTYLAPLLLKLA-SEHLAVRNKV 60
                5555666666666666666555.4555888765 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 1.8
     HEAT_EZ  45 RaaAagaLgnl 55 
                 +++A++aLg+l
  EEA20841.1 865 KENAIHALGQL 875
                 789******97 PP

  == domain 3  score: 1.4 bits;  conditional E-value: 0.1
     HEAT_EZ    5 raAawaLGr.......laggepellqplvpeilpaLlalLnddsdeV.Raa 47  
                  ++A+waL +       l+ g  + l+ ++ +   +L+     d deV +++
  EEA20841.1  969 ASAIWAL-ClvkdcgeLE-GVQQRLRAFQAAFAGLLA-----DRDEVvQET 1012
                  7899999.6333323133.444555556666666666.....777776776 PP

  == domain 4  score: 6.2 bits;  conditional E-value: 0.0035
     HEAT_EZ    1 wrvRraAawaLGr.laggepellqplvpeilpaLlalLnddsdeVRaaAagaL 52  
                  wrvR a ++a++  l g   e   +++ eil    + + d + +VR+aA++ +
  EEA20841.1 1188 WRVRQASCAAIADlLQGRSIEKYDKYLNEILSKAFKVMDDIKESVRTAALRLC 1240
                  9**********775333333334445556666655555444449999998875 PP

  == domain 5  score: 0.3 bits;  conditional E-value: 0.24
     HEAT_EZ   29 ilpaLl..alLnddsdeVRaaAagaLgn 54  
                  i+p+Ll   +++++ +eV+++A+ +L +
  EEA20841.1 1268 IIPFLLgqDGMESSAQEVQGYAISTLVQ 1295
                  8999999999999999******999855 PP

  == domain 6  score: -1.0 bits;  conditional E-value: 0.59
     HEAT_EZ   14 laggepellqplvpeilpaLlalLnd 39  
                  +    + ll+p+  +il  +l+ L++
  EEA20841.1 1297 IKKSPSALLRPFMAQILEKFLSSLSS 1322
                  555667899************88854 PP

  == domain 7  score: -1.5 bits;  conditional E-value: 0.89
     HEAT_EZ   17 gepellqplvpeilpaLlalLnddsdeVRaaAag 50  
                  g+p++++++++ei +    +L++++ +++  A+ 
  EEA20841.1 1527 GGPRAVALYLKEITAIISERLESSNWTIKHSACL 1560
                  899***********99999999998788888885 PP

  == domain 8  score: 0.8 bits;  conditional E-value: 0.17
     HEAT_EZ    3 vRraAawaLGrlaggepel.....lqplvpeilpaLlalLnddsdeVR 45  
                   R +A++aL+  a+  p+l       + v+ i++ L+     dsd+V+
  EEA20841.1 1640 YRPHALNALADFAEFQPDLdllsdAIKIVEPIVDDLV-----DSDNVK 1682
                  6899*****9855555555343332336666666666.....777775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1857 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       474  (0.0264376); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.02u 0.34s 00:00:01.36 Elapsed: 00:00:00.54
# Mc/sec: 10436.54
//
Query:       EEA20842.1  [L=1479]
Description: SNF2 family helicase/ATPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.1e-60  204.3   0.0    4.2e-60  203.3   0.0    1.5  1  SNF2_N        SNF2 family N-terminal domain
    3.1e-07   30.1  14.2    8.6e-07   28.7  14.2    1.8  1  zf-C3HC4_2    Zinc finger, C3HC4 type (RING finger)
    8.6e-07   28.7  14.2    2.2e-06   27.4  14.2    1.8  1  zf-C3HC4      Zinc finger, C3HC4 type (RING finger)
    1.1e-06   28.4  11.9    2.9e-06   27.0  11.9    1.7  1  zf-C3HC4_3    Zinc finger, C3HC4 type (RING finger)
    3.4e-06   27.4   0.0    8.5e-06   26.1   0.0    1.8  1  Helicase_C    Helicase conserved C-terminal domain
    9.2e-06   25.9  15.6    2.2e-05   24.7  15.6    1.7  1  zf-RING_2     Ring finger domain
    0.00027   20.8  11.6    0.00066   19.5  11.6    1.7  1  Prok-RING_4   Prokaryotic RING finger family 4
    0.00039   20.4  10.4    0.00098   19.1  10.4    1.7  1  zf-RING_UBOX  RING-type zinc-finger
    0.00079   19.5   0.0     0.0026   17.8   0.0    2.0  1  ResIII        Type III restriction enzyme, res subunit
     0.0078   16.5  12.4      0.023   15.0  12.4    1.8  1  zf-rbx1       RING-H2 zinc finger domain
  ------ inclusion threshold ------
      0.022   14.4   0.0      0.056   13.1   0.0    1.7  1  SWI2_SNF2     SWI2/SNF2 ATPase
      0.023   14.6   1.0       0.06   13.3   1.0    1.7  1  Baculo_IE-1   Baculovirus immediate-early protein (IE-0)
      0.041   13.9  14.0        0.1   12.6  14.0    1.7  1  zf-RING_5     zinc-RING finger domain
       0.16   12.2  11.7       0.33   11.1  11.7    1.6  1  zf-C3HC4_4    zinc finger of C3HC4-type, RING
        9.1    6.0  12.7         19    5.0  12.7    1.5  1  Zn_ribbon_17  Zinc-ribbon, C4HC2 type


Domain annotation for each model (and alignments):
>> SNF2_N  SNF2 family N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  203.3   0.0   3.5e-63   4.2e-60       1     348 [.     270     642 ..     270     644 .. 0.86

  Alignments for each domain:
  == domain 1  score: 203.3 bits;  conditional E-value: 3.5e-63
                 HHHHHHHHH...........................................................HHHHHTT--EEE---TTS--HHHHHHHHH.. CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxx....................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      SNF2_N   1 yQkeavkwmlkReqnlqdleaalrkllk....................tldgekiyvnpatgevveesaeakqsvrGGiLaDemGLGKTvqvlalilaq 79 
                 +Q++av+w+l++e  + d+   +                         + + +   + ++ ++ +++ +  +++ rGGiLa+emGLGKTv++++li  +
  EEA20842.1 270 FQNRAVRWLLEKEGMELDIYGNV----VpkkmeiaglpesfqeftdvdGRRCFSSQLYRVATTDMAPWYDSNRNLRGGILAEEMGLGKTVEMISLISLH 364
                 69*******88887665554333....133346899999******888666666666677788889999999*************************88 PP

                 .HHTTTS---.......S-EEEE--HHHHHHHHHHHHHH-TTS-EEE--SSHHHH-----------------EEEE-HHHHHHHT.............. CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........... RF
      SNF2_N  80 rakeekdkekkrkdtlagptLivvPaslldqWeneierhvsssalrvlvyggqkkmkkkntkvapklladydvvittYdvlsreaelq........... 167
                 r +  +d ++ +    + +tLi+ P ++l+qW++e+++h++s ++  + y+g +  +k  ++++ +ll+d+dvv+ttY+vl++e+++            
  EEA20842.1 365 RRAMVDDDAH-HSLIKSRATLIITPPAILEQWKQELQNHAPSLTV--FDYKGYQANSKLSQEQLSDLLRDTDVVLTTYNVLAKEVHRAtdppkrnmrne 460
                 8766666654.5666789***********************9965..77777777789999*********************999888*********** PP

                 .......TTS-S-S-SEEEES-GGGT--TTSHHHHHHHH---S-EEEE-S--SSS-HHHHHHHHHHH-TTTT--.HHHHHHHTHHHHHHHHHHHHHHHH CS
                 ....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxx RF
      SNF2_N 168 ....kkrsvlkqvewkrvvlDEghtlknstskaaeavskLstsnrwiltGTPiqnsledlygLlkfLreepfge.kqtfdkllqrpieaqaekgrsrLl 261
                     + +s+l++++w+rv+lDE+++++++ s+aa++++ +   n w +tGTPi  +++d++gLl+fLr epf+   + +++l++  +            
  EEA20842.1 461 krfkVPKSPLVRMSWWRVCLDEAQMIESGVSNAAQVARLIPRVNAWAVTGTPIRKDMRDFFGLLQFLRYEPFCGsIDLWSRLYSAYYP--------AFK 551
                 ***88899******************************9**********************************9899***99888887........899 PP

                 TT-STTEE---GGGT..--S---EEEEEEEEE--HHHHHHHH.....................HHHHHH-HH.H-HHHHHHHHHHHHH--- CS
                 xxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxx RF
      SNF2_N 262 qllqrlmlrrakkdv..eknlPpkteeiiflklskverksYnrllevlrkkalak.llkrseaalksssksk.ekilelllelrqacnhpq 348
                 +++++l lr++k+ +  + +lPp++  +i +++++ e++ Y +l e+++++     +    e   + +s+ +  k+ + l++lrq+c hp+
  EEA20842.1 552 SIVNKLALRHSKEFIrdDLKLPPQKRVVITIPFTAIEEQHYGQLFEQMCEDCGVDpTGAPLEQDWNPESQASiDKMRGWLTRLRQTCLHPE 642
                 ***************98889**********************9999988887654133334444555555566778999********9997 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.7  14.2   7.2e-10   8.6e-07       2      40 .]    1131    1168 ..    1130    1168 .. 0.98

  Alignments for each domain:
  == domain 1  score: 28.7 bits;  conditional E-value: 7.2e-10
  zf-C3HC4_2    2 CpiCldmlkdpsvvtpCgHvfCqkCilrsLeekneCPlC 40  
                  C iC+  ++++ v+t CgH++C++C++ +++++  CP+C
  EEA20842.1 1131 CIICQCTFENG-VLTVCGHKYCKDCLRVWWHQHRTCPTC 1168
                  **********9.*************************** PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.4  14.2   1.8e-09   2.2e-06       1      41 []    1131    1168 ..    1131    1168 .. 0.99

  Alignments for each domain:
  == domain 1  score: 27.4 bits;  conditional E-value: 1.8e-09
                  -TTT-S--SS-E.E-TTS--B-CHHHHHHHHCTSSB--TTT CS
    zf-C3HC4    1 CpiCleeakepnelleCkHsfCskCirkilksrkkvkCPlC 41  
                  C+iC++++++ + l+ C+H++C++C+r ++   ++++CP+C
  EEA20842.1 1131 CIICQCTFENGV-LTVCGHKYCKDCLRVWWH--QHRTCPTC 1168
                  ************.******************..999***** PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.0  11.9   2.5e-09   2.9e-06       3      47 ..    1129    1172 ..    1127    1174 .. 0.94

  Alignments for each domain:
  == domain 1  score: 27.0 bits;  conditional E-value: 2.5e-09
                  SB-TTTSSSBS-EEETTEEEEEE-HHHHHHHHHTT-B-TTT--B- CS
  zf-C3HC4_3    3 eeCviClerprnvvllpCgHlvlCeeCaekllkrkkkCpiCrrpi 47  
                  ++C+iC+ + +n vl  CgH  +C++C++ ++ ++++Cp C+r  
  EEA20842.1 1129 RLCIICQCTFENGVLTVCGHK-YCKDCLRVWWHQHRTCPTCKRTL 1172
                  68*******************.*******************9975 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.1   0.0   7.1e-09   8.5e-06       4     111 .]    1234    1339 ..    1231    1339 .. 0.78

  Alignments for each domain:
  == domain 1  score: 26.1 bits;  conditional E-value: 7.1e-09
                  HHHHHHH...HHTTTTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHH.TTSSS.EEEESGGGTSSSTSTTESEEEESSSSS CS
  Helicase_C    4 eallell...kleeeggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfn.kgesd.vLiatdvaerGidipkvnlVinfdlpr 95  
                  ++l + l    ++  g k+++f++++d l    +l + +  ++ + +++ ++   ++ +++f+ +     +L+  ++ + G+++ ++++V+ +++  
  EEA20842.1 1234 DTLSRHLmwlREHDPGAKSIVFSQYRDFL---GVLATAF-SRFKIGYSSVEA---KDGIQRFKeDPAAEcFLLHARAHSSGLNLVNATHVFLCEPLI 1323
                  555555556678999************99...7885555.555555565555...55666666423334499************************* PP

                  SHHHHHHHHTTSSSTT CS
  Helicase_C   96 nvtsyiqriGRtgRag 111 
                  n++   q+i R++R+g
  EEA20842.1 1324 NTAIELQAIARVHRIG 1339
                  **************97 PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7  15.6   1.9e-08   2.2e-05       3      44 .]    1131    1169 ..    1129    1169 .. 0.90

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 1.9e-08
   zf-RING_2    3 CpICleelssadsvlllpCgHvfhreClerwlrssstCPlCr 44  
                  C IC++ ++  + vl++ CgH ++++Cl+ w ++++tCP+C+
  EEA20842.1 1131 CIICQCTFE--NGVLTV-CGHKYCKDCLRVWWHQHRTCPTCK 1169
                  *****9997..566666.***********************7 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5  11.6   5.6e-07   0.00066       1      43 [.    1131    1175 ..    1131    1178 .. 0.90

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 5.6e-07
  Prok-RING_4    1 CvlCgeqekkailepCgHlvCkeCfdsk..dlssCPlCqrrisks 43  
                   C++C+   ++ +l  CgH  Ck+C+  +  ++ +CP C+r ++++
   EEA20842.1 1131 CIICQCTFENGVLTVCGHKYCKDCLRVWwhQHRTCPTCKRTLKAN 1175
                   ****************************66666*******99765 PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1  10.4   8.2e-07   0.00098       1      39 []    1131    1166 ..    1131    1166 .. 0.90

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 8.2e-07
  zf-RING_UBOX    1 CpIClelftdPlv.lpCGHtFCreClwelskslegafkCP 39  
                    C IC+ +f++  v + CGH +C++Cl   + + +++++CP
    EEA20842.1 1131 CIICQCTFENG-VlTVCGHKYCKDCL---RVWWHQHRTCP 1166
                    99******998.5247**********...8999******9 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   2.2e-06    0.0026      21     122 ..     318     455 ..     264     514 .. 0.69

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 2.2e-06
                 .....................TTSEEEEEESTTSTHHHHHHHHHHHH-S..............-EEEEESSHHHHHHHHHHGGGGTGG..........G CS
      ResIII  21 s...................krdkrglikmaTGtGKTlvaaklierllkkgkee.........kflflvprkslleqtleefkkflseayke......i 85 
                                     ++ + g+++ + G GKT+ +++li   +++   +         ++ +++   ++leq+++e+++ +++ + +      +
  EEA20842.1 318 FssqlyrvattdmapwydsnRNLRGGILAEEMGLGKTVEMISLISLHRRAMVDDdahhsliksRATLIITPPAILEQWKQELQNHAPSLTVFdykgyqA 416
                 055555555555555655534445788999**************999888776699999****999999999**************9998776655554 PP

                 EEEESSS-B--.......-SEEEEEHHHHHHTH......... CS
      ResIII  86 gkkvsgdkkkakekdstnkkilvttiqsldadseee.....e 122
                 + k+s+++ +       ++++++tt++ l ++ +++     +
  EEA20842.1 417 NSKLSQEQLSD---LLRDTDVVLTTYNVLAKEVHRAtdppkR 455
                 44444444444...78999************99776554441 PP

>> zf-rbx1  RING-H2 zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0  12.4   1.9e-05     0.023      12      55 .]    1129    1169 ..    1125    1169 .. 0.86

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.9e-05
     zf-rbx1   12 eacieckapgdeecpvvlGeCgHaFHlhCiskWlktrkvCPlcr 55  
                  + ci c+ + ++    vl  CgH++ ++C++ W +++++CP+c+
  EEA20842.1 1129 RLCIICQCTFEN---GVLTVCGHKYCKDCLRVWWHQHRTCPTCK 1169
                  578888888887...56668***********************6 PP

>> SWI2_SNF2  SWI2/SNF2 ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   4.7e-05     0.056      19     163 ..     341     518 ..     321     529 .. 0.64

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 4.7e-05
   SWI2_SNF2  19 kgGviWHtqGSGKsltmvflakklle.eelknpkvvvvtDRkdL.......dkQlsktfaka.........geekpkqaesrkeLkellekesekiift 100
                 +gG++    G GK+++m+ l +  ++    ++++  ++  R  L        +Q ++++++          +  +++++ s+++L +ll  +++++++t
  EEA20842.1 341 RGGILAEEMGLGKTVEMISLISLHRRaMVDDDAHHSLIKSRATLiitppaiLEQWKQELQNHapsltvfdyKGYQANSKLSQEQLSDLL--RDTDVVLT 437
                 66777777777777777777666555212233333333333333111111134555555554333333333233445777889999999..46899999 PP

   SWI2_SNF2 101 tiqKfeeeek..................eklevlsereniivlvDEaHRsqyg.elakklrkalpnaafigFTGTPilkkdk 163
                 t + +++e +                   k + l + + + v  DEa   ++g + a+++ + +p+    + TGTPi k+ +
  EEA20842.1 438 TYNVLAKEVHratdppkrnmrnekrfkvPK-SPLVRMSWWRVCLDEAQMIESGvSNAAQVARLIPRVNAWAVTGTPIRKDMR 518
                 988887442234567777788776654322.3445555699*********99977899*******************98765 PP

>> Baculo_IE-1  Baculovirus immediate-early protein (IE-0)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   1.0     5e-05      0.06       8     135 ..    1051    1176 ..    1029    1181 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 5e-05
  Baculo_IE-1    8 ekfeknvyiflpylkqlrkilklfvndycckklvkklkaal.delleesekslevikline.rvqvlnvflek....klyqcnicedtsaeerflk 97  
                   e f+  +   l y kql++i +  +  y  +++ k l +a+ d+ le  +k  + + ++++ r  ++ + +e+        c ic+ t+ +     
   EEA20842.1 1051 ELFRDTMNNRLEYYKQLQQISDTVA-PYDEESVGKPLDQAVyDSKLEAENKIQQKLDSLQSkRRYLIHLRDESgpdeSTRLCIICQCTFENGVL-- 1143
                   5677777777889999998887654.3334556665555441555666666666677665404455555544332326778****999877653.. PP

  Baculo_IE-1   98 PneccGykicnlcyanlwkfstvyPvcPvcktsfksss 135 
                     + cG+k c+ c    w+    + +cP ck + k+++
   EEA20842.1 1144 --TVCGHKYCKDCLRVWWH---QHRTCPTCKRTLKAND 1176
                   ..69*********977775...5789*****9999865 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6  14.0   8.5e-05       0.1       2      43 ..    1131    1169 ..    1130    1170 .. 0.95

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 8.5e-05
   zf-RING_5    2 CnkCfeklskeekfyltsCgHifCekClkkllekeavCpiCr 43  
                  C +C + +   e+ +lt CgH +C++Cl+   ++ ++Cp+C+
  EEA20842.1 1131 CIICQCTF---ENGVLTVCGHKYCKDCLRVWWHQHRTCPTCK 1169
                  999*****...9******************999********9 PP

>> zf-C3HC4_4  zinc finger of C3HC4-type, RING
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1  11.7   0.00028      0.33       1      42 []    1131    1168 ..    1131    1168 .. 0.93

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00028
  zf-C3HC4_4    1 CPiCldYLekPvsleCGhsfClsCisslqkepdgeqllCplC 42  
                  C iC   +e+ v   CGh +C  C+  ++++      +Cp C
  EEA20842.1 1131 CIICQCTFENGVLTVCGHKYCKDCLRVWWHQH----RTCPTC 1168
                  99***************************988....469999 PP

>> Zn_ribbon_17  Zinc-ribbon, C4HC2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0  12.7     0.016        19       3      47 ..    1127    1167 ..    1125    1170 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.016
  Zn_ribbon_17    3 llksCayCelavkgrvvlcgvCeHvlHasCarewfenddlaeCps 47  
                    +++ C +C+ + +  v   +vC+H   ++C+r w+++     Cp+
    EEA20842.1 1127 STRLCIICQCTFENGV--LTVCGHKYCKDCLRVWWHQHR--TCPT 1167
                    6889****99998765..479***************999..8886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1479 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1070  (0.0596798); expected 358.6 (0.02)
Passed bias filter:                      560  (0.0312343); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.97u 0.32s 00:00:01.29 Elapsed: 00:00:00.51
# Mc/sec: 8675.95
//
Query:       EEA20843.1  [L=679]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.7e-189  629.5   1.0   3.5e-189  629.2   1.0    1.1  1  PNGaseA   Peptide N-acetyl-beta-D-glucosaminyl asparaginase a
  ------ inclusion threshold ------
      0.089   12.4   0.0        1.2    8.8   0.0    2.4  3  DUF4131   Domain of unknown function (DUF4131)


Domain annotation for each model (and alignments):
>> PNGaseA  Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  629.2   1.0  3.9e-193  3.5e-189       1     434 []     127     551 ..     127     551 .. 0.99

  Alignments for each domain:
  == domain 1  score: 629.2 bits;  conditional E-value: 3.9e-193
     PNGaseA   1 PvetpkgsekckeevlllehtFgnsygkPfvgkytpPecsfdrvvlnltvtssGrqydRlallylgdvevwRTSTaepttagivwtylKdvseYlaLfk 99 
                 Pve ++ s+ c++ +ll+eh+Fg+syg+Pfvg++tpP+c+fd+v++nltvts+Grq+dRlal+yl+d+ev+RTSTaeptt+givwty+K++s+Yl+L+k
  EEA20843.1 127 PVEFDPPSQGCDQVILLMEHSFGYSYGQPFVGSFTPPDCDFDTVRINLTVTSRGRQFDRLALMYLNDTEVFRTSTAEPTTNGIVWTYIKEMSQYLTLWK 225
                 8888999999***************************************************************************************** PP

     PNGaseA 100 epqklifdLgNliddtytgsfnvtltatfyaseelletaeaadlilpisarksasnsssafslpsdkatvtlslprntsravlsisasgqaaeEfWysN 198
                 +pqk+ifdLgNlid++ytg fn+tlta+f++++    ++++adlilpisarks ++++saf++psd+atv l++p+n++rav+sisa+gq++eEfW+s 
  EEA20843.1 226 TPQKIIFDLGNLIDSKYTGPFNTTLTASFTKEN----NVRMADLILPISARKSVNDAASAFNVPSDNATVDLTFPSNAQRAVVSISACGQSEEEFWWSG 320
                 ********************************9....************************************************************** PP

     PNGaseA 199 vlssdteafedtvgelyghspfRevqvlidGqlagvvwPfpviftGGisPglwrPivgidafDlreleiditpfLplLldgedheleikvagledeeeg 297
                 vl++dt++f++t g+lyg+spfRevq++idG lagvvwPfpviftGG++Pg+wrPivgidafDlre+eidi+pfLplLldg++h++eikvagl+  +++
  EEA20843.1 321 VLNQDTDDFDSTIGVLYGYSPFREVQLYIDGLLAGVVWPFPVIFTGGVAPGFWRPIVGIDAFDLREPEIDISPFLPLLLDGTTHSFEIKVAGLDIPSSN 419
                 *************************************************************************************************** PP

     PNGaseA 298 tatlsktvgsyWvvtgnlfvwldssskesegtivetdtkpeikakapslkvtreleqnsatgtneslsytveaerslsvesttvtwsqklsfsntqlls 396
                 ++tl++tv+syWvvtg++f++l++s    ++ti+ t+ +p i+a+  +++++r+l++n  ++tne+lsy+v+a+r+l+++s +++w+q+lsf n ++l+
  EEA20843.1 420 DKTLTQTVNSYWVVTGKVFIYLNDSG---KTTIKPTGVPPAISASDLQFSFSRNLVSN--STTNETLSYSVSAHRTLKIRSGSSSWTQDLSFYNDGYLN 513
                 *************************9...899*************************9..789************************************ PP

     PNGaseA 397 qqglsqsvnqttsgkstvtekseakesdevevsfsyPl 434
                 q+g+sq ++q+t+g+s ++ ++ + ++ e++++fsyPl
  EEA20843.1 514 QNGMSQRNTQNTTGTSIAKGFGLDGKMVEFKTTFSYPL 551
                 *************************************8 PP

>> DUF4131  Domain of unknown function (DUF4131)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   0.0   0.00013       1.2       7      90 ..      13     142 ..       8     160 .. 0.80
   2 ?   -3.5   0.0      0.81   7.2e+03      69     106 ..     170     207 ..     167     213 .. 0.77
   3 ?    0.5   0.0     0.047   4.2e+02      66     122 ..     401     451 ..     378     453 .. 0.66

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00013
     DUF4131   7 lvllalllllllllllllrr........................................rprrrvllllllllllallgfalrapqpnandlsqlles 65 
                 lv++++ +++++ l+l+++r                                        r++  + ++++l+l l++l+ ++ a++ na+++ +   s
  EEA20843.1  13 LVVILIPVWAICRLILWSQRthqsptilpydtiksdtgsakerkndltfacnlksykaasRRTDFMKISAALCLSLFGLYSFVAAYNDNATHFLRRQAS 111
                 677888888888888888889999999999999999999999888888888888888766666666999999999999999999999999776665555 PP

     DUF4131  66 ...gqeviveGvvaslpeltgsgt...rfvl 90 
                    + +v+v   v + +e ++ ++   +++l
  EEA20843.1 112 atnSSSVLVDFQVYKPVEFDPPSQgcdQVIL 142
                 78899999999**999999988776666665 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 0.81
     DUF4131  69 viveGvvaslpeltgsgtrfvlevervlsagktkpvsg 106
                 v +  +v+s+ ++ ++ + ++l+ ++v++++  +p++ 
  EEA20843.1 170 VRINLTVTSRGRQFDRLALMYLNDTEVFRTSTAEPTTN 207
                 66777899999999888888888888888777777665 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.047
     DUF4131  66 gqeviveGvvaslpeltgsgtrfvlevervlsagktkpvsgrvlvtvpkspaeglrp 122
                 g++  +e +va l   + + + ++      ++ +    v+g+v +++++s  ++++p
  EEA20843.1 401 GTTHSFEIKVAGLDIPSSNDKTLT------QTVNSYWVVTGKVFIYLNDSGKTTIKP 451
                 444445555544444444444222......566778899*********999998887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (679 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       552  (0.0307881); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.44
# Mc/sec: 4632.77
//
Query:       EEA20844.1  [L=353]
Description: oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.9e-66  222.9   0.0    5.6e-66  222.7   0.0    1.0  1  Aldo_ket_red  Aldo/keto reductase family
  ------ inclusion threshold ------
       0.14   11.5   0.0        0.2   11.1   0.0    1.1  1  SDA1          SDA1


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  222.7   0.0   6.2e-70   5.6e-66       2     292 ..      16     342 ..      15     344 .. 0.95

  Alignments for each domain:
  == domain 1  score: 222.7 bits;  conditional E-value: 6.2e-70
                   EEEE-SSS-ST.....TS-HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH-TTTGGG-EEEEEE........................ CS
  Aldo_ket_red   2 lglGtwqlgsk....eeiskeealellrraleaGinffDtAevYgkgqseellGealkksrkkreeviiatKv........................ 70 
                   +++G+++lgs     ++i++++al +l++a++ Gin++Dt++vY  g+se+++G+alk+++  r  v+i tK+                        
    EEA20844.1  16 VIFGAMSLGSSdhmqWAIPEDQALPILKHAFDLGINTWDTSDVYSFGESERIIGKALKHYNIARGRVVILTKCyggvpepadfvgrseeeklrmlsv 112
                   79*********************************************************************************************** PP

                   --SSSTTSSSS-HHHHHHHHHHHHHHHT-S-EEEEEE-S--TTS-.HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHH....HHTTT--EEEEE-B CS
  Aldo_ket_red  71 dlrdaeiksglskeniresleeslkrLgtdyvDllllHrpdpslpsieevldaleelvkeGkiraiGvSnfsveqleka....kkkkkvkivavqve 163
                   +++++ +++gls+++i  ++++s++rLgt y+D+l++Hr d+++p +ee+++al+++v++Gk+r++G S+  ++  +++     k++ +k+++ q  
    EEA20844.1 113 NDGIMVNQVGLSRKHIFDAVDASVERLGT-YIDVLQIHRLDRNTP-REEIMKALNDVVESGKVRYLGASSMHAWEFQALnniaDKHGWHKFISMQDY 207
                   ****************************6.***************.**************************9999999999*************** PP

                   -BTT-HHHHTTHHHHHHHTT-EEEEBSTTGGGTTGTTTSS---SSSCCC-------....TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTSTT CS
  Aldo_ket_red 164 ynllreleeegllelckkkgvpliaysplggGlltgkyqseedkedkeprkdlkrd....ertsknldaaeelselakehgvslaqlalryalsqpa 256
                   ++ll ++ee+++  +c++ gv++i++spl++Gll + y+  ++ ++  + +d  ++    + t+   + +++++ela ++ +s+aq+a+++ l  ++
    EEA20844.1 208 HSLLYREEEREMHAYCRDAGVGIIPWSPLARGLLARPYKVTQEQPTLRQTSDVYSRflvgDVTEADVKIINRVEELADKKHCSMAQIAIAWSL--KK 302
                   ***********************************9999998888887777777779************************************..99 PP

                   -SEEEE--SSHHHHHHHHGGGG-....---HHHHHHHHHH CS
  Aldo_ket_red 257 vgivipgasnieqlednldalel....klseeevaeldel 292
                   ++ +i+g  +++++++ ++a++l     l++e+++ ld+l
    EEA20844.1 303 GVNPIVGLASVKRVDEAAEAVALaskgLLTDEDFKSLDKL 342
                   999999999999999999987543225699****999997 PP

>> SDA1  SDA1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   2.2e-05       0.2     197     223 ..     317     343 ..     278     349 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 2.2e-05
        SDA1 197 ekiskaselattrILTpaDFaklkelr 223
                 +++++a  la++ +LT++DF+ l++l 
  EEA20844.1 317 DEAAEAVALASKGLLTDEDFKSLDKLY 343
                 44556667****************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (353 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       411  (0.0229238); expected 358.6 (0.02)
Passed bias filter:                      375  (0.0209158); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2441.29
//
Query:       EEA20845.1  [L=581]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.8e-17   61.8   0.0      1e-16   61.0   0.0    1.4  1  DUF3425   Domain of unknown function (DUF3425)


Domain annotation for each model (and alignments):
>> DUF3425  Domain of unknown function (DUF3425)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.0   0.0   5.8e-21     1e-16      12     122 ..     454     561 ..     449     563 .. 0.86

  Alignments for each domain:
  == domain 1  score: 61.0 bits;  conditional E-value: 5.8e-21
     DUF3425  12 eeaveklpenlrPtelQlriaHpveidvlpwpelRdrllr..afqeeeidedeffrdvvs.tlivWsieeeeletaeissaelsagdvtdlegWelkes 107
                 +e+++ + + lrPt  Q+r  H++++d lp+p lR+r+++  + +   ide+++++d+ + +li+W       + +   +  +  g ++d ++We++++
  EEA20845.1 454 KERFDDVAPHLRPTIAQIRHSHHPYLDGLPFPSLRERIIEacSLEPPIIDEEDLCNDLEKgGLICWG------SYLGNGNCATGSGAPWDYRSWEAQPW 546
                 57788899********************************77667778**********8889****8......33334444556689************ PP

     DUF3425 108 FfrkYpylvdglele 122
                 F+rk++  + g + e
  EEA20845.1 547 FLRKWWFFIGGSQAE 561
                 ********9997665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (581 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       403  (0.0224776); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 3847.85
//
Query:       EEA20846.1  [L=225]
Description: DnaJ chaperone (Caj1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.2e-21   74.9   0.7    6.5e-21   74.2   0.7    1.3  1  DnaJ             DnaJ domain
     0.0057   16.8   2.6      0.011   15.8   2.6    1.4  1  Bacteriocin_IIc  Bacteriocin class II with double-glycine lea
  ------ inclusion threshold ------
      0.025   14.9   1.3      0.037   14.3   1.3    1.2  1  DUF456           Protein of unknown function (DUF456)
       0.26   11.3  10.0       0.51   10.4  10.0    1.5  1  Gly-zipper_Omp   Glycine zipper
        5.2    6.9  12.7         17    5.3  12.9    1.7  1  Gly-zipper_YMGG  YMGG-like Gly-zipper


Domain annotation for each model (and alignments):
>> DnaJ  DnaJ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.2   0.7   1.8e-24   6.5e-21       1      63 []       6      72 ..       6      72 .. 0.92

  Alignments for each domain:
  == domain 1  score: 74.2 bits;  conditional E-value: 1.8e-24
                HHHHHHTSSTTG-HHHHHHHHHHHHHHHSTTTS....CCHHHHHHHHHHHHHHHHHHTSHHHHHHHH CS
        DnaJ  1 dyYeiLgvskdasedeIkkaYrklalkyHPDkn....pkdpeaeekFkeineAyevLsdpekRkqYD 63
                dyY++Lgvs++a+++eI+ aY++ +l+ HPD+     p+  + +++F+++n+Ay +Lsdp++R++YD
  EEA20846.1  6 DYYKVLGVSPTATQQEIRTAYKRASLRTHPDRVpvdaPDRASRTKQFQKVNDAYYTLSDPSRRRDYD 72
                8******************************77444355559999*********************9 PP

>> Bacteriocin_IIc  Bacteriocin class II with double-glycine leader peptide
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   2.6     3e-06     0.011      34      59 ..     156     181 ..     137     187 .. 0.65

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 3e-06
  Bacteriocin_IIc  34 aGaatGaatlgilgaavGavvGavvG 59 
                       Ga++G+a++ i++ ++Ga++Gav+G
       EEA20846.1 156 VGAISGGALGFIVANVPGALAGAVAG 181
                      45555555555588889999998887 PP

>> DUF456  Protein of unknown function (DUF456)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   1.3     1e-05     0.037      62      94 ..     153     185 ..     147     195 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 1e-05
      DUF456  62 rgligaivGaivGffllpplGlllgpflgaflg 94 
                 ++++gai G+ +Gf++  ++G+l+g+++g  lg
  EEA20846.1 153 WSIVGAISGGALGFIVANVPGALAGAVAGNRLG 185
                 99***********99999*********997666 PP

>> Gly-zipper_Omp  Glycine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4  10.0   0.00014      0.51       4      36 ..     155     186 ..     154     195 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00014
  Gly-zipper_Omp   4 aiGAaaGaliGgavggrgtGaliGAavGaavGg 36 
                     ++GA+ G+++G +v + + Gal+GA++G  +G+
      EEA20846.1 155 IVGAISGGALGFIVAN-VPGALAGAVAGNRLGA 186
                     5899999999999998.7888888888877776 PP

>> Gly-zipper_YMGG  YMGG-like Gly-zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3  12.9    0.0047        17       9      43 ..     156     188 ..     154     193 .. 0.77

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0047
                      XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Gly-zipper_YMGG   9 iGAaaGAvvGaliGsgggkGAaiGAaaGalaGgai 43 
                      +GA++G ++G ++   +  GA+ GA+aG   G+++
       EEA20846.1 156 VGAISGGALGFIVA--NVPGALAGAVAGNRLGAVR 188
                      57777777777777..9999999999998888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (225 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       403  (0.0224776); expected 358.6 (0.02)
Passed bias filter:                      357  (0.0199119); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 1489.42
//
Query:       EEA20847.1  [L=269]
Description: phosphomannomutase (Sec53), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
   1.6e-103  345.2   0.1   1.9e-103  345.0   0.1    1.0  1  PMM          Eukaryotic phosphomannomutase
  ------ inclusion threshold ------
      0.031   14.0   0.0       0.25   11.0   0.0    2.0  2  Hydrolase_3  haloacid dehalogenase-like hydrolase
       0.13   11.5   0.1       0.17   11.1   0.1    1.1  1  TMPIT        TMPIT-like protein


Domain annotation for each model (and alignments):
>> PMM  Eukaryotic phosphomannomutase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  345.0   0.1  3.1e-107  1.9e-103       3     220 ..      43     268 ..      41     269 .] 0.96

  Alignments for each domain:
  == domain 1  score: 345.0 bits;  conditional E-value: 3.1e-107
                 HHHHHHCTTSEEEEE-SS-HHHHHHHHS...TTHHHH-SEEEEGGGTEEEETTEEEEE--HHHHH-HHHHHHHHHHHHHHHHCS--S---S-SEEEESS CS
         PMM   3 eflqklrkkveigvvgGsdlekikeqla..gdevldefdyvfsenGlvaykkgkelasqsiiealgeeklkklinfvlryladldlPvkrGtfiefrng 99 
                  +l+klr+k++ig vgGsd++k++eql+    +v++ fd++fsenGl a++ gk las s+i++lgeek++++ nf l+yl++++lP krGtfiefr g
  EEA20847.1  43 TLLSKLRHKCAIGYVGGSDFSKQQEQLGssTVSVTSLFDFCFSENGLNAFRLGKPLASTSFIQWLGEEKYQNMANFLLKYLSEVKLPRKRGTFIEFRTG 141
                 6899***********************955557899*************************************************************** PP

                 EEEE-SS-TTSSHHHHHHHHHHHHHHTHHHHHHHHHHHHTTTSSEEEEEETTTEEEEEETT-SGGGGGGGCTTST......-SEEEEEESS-STTSTTH CS
         PMM 100 llnvsPiGrnasqeernefeeydkkekireklvealkeefadlgltfsiGGqisfdvfPkgWdktyclqhvekds......fdeihffGdktaeGGndy 192
                 l+nvsPiGrnas eernefeeydk ++ir+ lvealk+ef d+glt+siGGqisfdvfP+gWdktycl+h+e+++      +++ihffGdk  +GGndy
  EEA20847.1 142 LINVSPIGRNASVEERNEFEEYDKVHNIRKDLVEALKKEFPDYGLTYSIGGQISFDVFPTGWDKTYCLRHIEAEKditgieYKNIHFFGDKCFPGGNDY 240
                 ***********************************************************************98744455569***************** PP

                 HHHHSTTCEEEE-SSHHHHHHHHHHHHT CS
         PMM 193 eiyadprtighsvtspddtvkkleellk 220
                 eiy+dprtighsvt+pddt+k+l+el++
  EEA20847.1 241 EIYTDPRTIGHSVTGPDDTMKQLKELFQ 268
                 **************************97 PP

>> Hydrolase_3  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0     0.052   3.1e+02       1      29 [.      22      50 ..      22      57 .. 0.90
   2 ?   11.0   0.0   4.2e-05      0.25     152     212 ..     168     232 ..     109     243 .. 0.81

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.052
                 EEEEIIIIIS-TTS---HHHHHHHHHHHH CS
  Hydrolase_3  1 ialDlDGTLlnsdkkisektkeaikklke 29
                 + +D+D TL    ++ s++    + kl+ 
   EEA20847.1 22 VLFDVDKTLSPARGTASPEMLTLLSKLRH 50
                 579*****************999999985 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 4.2e-05
                  HHHHHHHHHHHHHCTTTE.EEEEESTTEEEEEETT-SHHHHHHHHH...HHCT--GGGEEEEESS CS
  Hydrolase_3 152 ekldelekelksklnkll.titssskgyleimpkgvsKgtalkkla...kelnisleeviafGDg 212
                  +  ++l ++lk+++++   t++  ++ ++++ p g++K   l+++       +i+ +++  fGD+
   EEA20847.1 168 NIRKDLVEALKKEFPDYGlTYSIGGQISFDVFPTGWDKTYCLRHIEaekDITGIEYKNIHFFGDK 232
                  34455666666666665479999**********************93334456788999999995 PP

>> TMPIT  TMPIT-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.1   2.9e-05      0.17      85     130 ..     124     169 ..     100     186 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 2.9e-05
       TMPIT  85 vesllpkknglylklvlGnvnvsllnkqdkfkyKdeYekFklkltv 130
                  e  lp+k+g++++   G +nvs + +++ ++ ++e+e++ ++ ++
  EEA20847.1 124 SEVKLPRKRGTFIEFRTGLINVSPIGRNASVEERNEFEEYDKVHNI 169
                 4678************************************877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (269 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       368  (0.0205254); expected 358.6 (0.02)
Passed bias filter:                      349  (0.0194657); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 1881.94
//
Query:       EEA20848.1  [L=1275]
Description: pre-mRNA splicing factor (Prp24), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.1e-51  171.6   0.1    5.7e-18   64.5   0.0    4.6  4  RRM_1            RNA recognition motif. (a.k.a. RRM, RBD, or 
    1.2e-35  121.2   0.0    1.2e-27   95.5   0.0    4.3  4  RRM_occluded     Occluded RNA-recognition motif
    6.1e-09   35.7   0.0     0.0035   17.3   0.0    3.7  3  Nup35_RRM_2      Nup53/35/40-type RNA recognition motif
    0.00035   20.6   1.9       0.65   10.1   0.0    4.3  4  RRM_3            RNA binding motif
  ------ inclusion threshold ------
      0.092   12.3   0.7       0.24   11.0   0.7    1.8  1  Lsm_interact     Lsm interaction motif
          1   10.3   5.3        4.7    8.3   0.0    4.5  4  TPR_14           Tetratricopeptide repeat
        9.9    6.0  11.7         51    3.7  11.7    2.2  1  Spore_coat_CotO  Spore coat protein CotO


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.1   0.0   3.9e-13     1e-09       1      69 [.     834     899 ..     834     900 .. 0.93
   2 !   44.8   0.0   3.1e-15   7.9e-12       1      65 [.     909     972 ..     909     974 .. 0.95
   3 !   64.5   0.0   2.2e-21   5.7e-18       2      69 ..    1001    1067 ..    1000    1068 .. 0.97
   4 !   18.6   0.0   4.6e-07    0.0012       5      64 ..    1118    1172 ..    1114    1179 .. 0.92

  Alignments for each domain:
  == domain 1  score: 38.1 bits;  conditional E-value: 3.9e-13
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkklggrel 69 
                 ++V+  p+d+ e++++++F+++Gpi++ik  +   +    +a VeFe++edA++Al   + k ++g+++
  EEA20848.1 834 VMVKRMPSDIIESQIRQFFRDCGPIVDIKFLPS--EHDLTTAVVEFETQEDAAAALT-RDQKRINGQTV 899
                 689*****************************5..888899****************.99999999876 PP

  == domain 2  score: 44.8 bits;  conditional E-value: 3.1e-15
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEET CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkklg 65 
                 ++V+n+pp+++e  ++ lFs+ G+i++++ ++ + +++++f++V+F+s+++A +A + l++  +g
  EEA20848.1 909 VYVTNFPPTADEAFIRSLFSEAGEIVEVRFPSLKYNTHRRFCYVQFKSPDQAIAATK-LDNNVVG 972
                 8******************************************************99.8887665 PP

  == domain 3  score: 64.5 bits;  conditional E-value: 2.2e-21
                  EEESETTTSSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1    2 fVgnLppdvteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkklggrel 69  
                   ++n+++d+ e++LkelFsk+G i++++++++ +g ++gf+f+ F +ke+A++Al+ ++++ ++gr+l
  EEA20848.1 1001 HISNIHFDARENDLKELFSKYGTIETVRIPSKVNGEHRGFGFIVFSKKEEATAALA-MHKQDFRGRPL 1067
                  599*****************************************************.*********97 PP

  == domain 4  score: 18.6 bits;  conditional E-value: 4.6e-07
                  SETTTSSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEE CS
       RRM_1    5 nLppdvteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkkl 64  
                  n+p +v+++ ++++ ++fGp ++i l +d     +  a+VeF +  +A kA  +l g ++
  EEA20848.1 1118 NIPDTVNDSRIRAIAEPFGPLVKIILRPD-----REGAIVEFVDIKAAGKASLELEGHEI 1172
                  99**************************9.....*****************999999665 PP

>> RRM_occluded  Occluded RNA-recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   4.7e-06     0.012       3      68 ..     833     899 ..     831     904 .. 0.81
   2 ?    0.7   0.0      0.18   4.7e+02       3      33 ..     908     937 ..     906     973 .. 0.79
   3 ?    3.5   0.0     0.025        63      17      70 ..    1013    1069 ..     997    1072 .. 0.70
   4 !   95.5   0.0   4.9e-31   1.2e-27       1      78 [.    1111    1188 ..    1111    1189 .. 0.96

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 4.7e-06
  RRM_occluded   3 tisllplsDtvnkariralveekegeikkivLvp...dheGAivefkdekiagkasLaLdgsefegkkl 68 
                   t+ +  ++  + +++ir+++ +  g+i++i   p   d   A+vef+ +++a+ a+L  d ++++g+++
    EEA20848.1 833 TVMVKRMPSDIIESQIRQFFRDC-GPIVDIKFLPsehDLTTAVVEFETQEDAA-AALTRDQKRINGQTV 899
                   5666678888999**********.******99884334579**********99.567778888887775 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.18
  RRM_occluded   3 tisllplsDtvnkariralveekegeikkiv 33 
                   t+ + +++ t  +a ir+l++e  gei+++ 
    EEA20848.1 908 TVYVTNFPPTADEAFIRSLFSEA-GEIVEVR 937
                   788999999**************.9998874 PP

  == domain 3  score: 3.5 bits;  conditional E-value: 0.025
  RRM_occluded   17 riralveekegeikkivLvp....dheGAivefkdekiagkasLaLdgsefegkklrc 70  
                     +++l++++ g i+ + + +    +h+G   ++ ++k  + a+La++ ++f g+ l++
    EEA20848.1 1013 DLKELFSKY-GTIETVRIPSkvngEHRGFGFIVFSKKEEATAALAMHKQDFRGRPLQV 1069
                    567777777.777777665511114555444444566677899***********9986 PP

  == domain 4  score: 95.5 bits;  conditional E-value: 4.9e-31
  RRM_occluded    1 ertisllplsDtvnkariralveekegeikkivLvpdheGAivefkdekiagkasLaLdgsefe.gkklrcGtvkdLkk 78  
                    +rt++l++++Dtvn++rira+ e+  g+++ki+L+pd eGAivef d k+agkasL+L+g+e++ g+ +r+Gt +d  k
    EEA20848.1 1111 ARTLGLMNIPDTVNDSRIRAIAEPF-GPLVKIILRPDREGAIVEFVDIKAAGKASLELEGHEIApGRLIRVGTANDVLK 1188
                    59***********************.*************************************77**********9765 PP

>> Nup35_RRM_2  Nup53/35/40-type RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0   1.4e-06    0.0035      15      53 .]     846     887 ..     840     887 .. 0.86
   2 !   12.3   0.0   4.8e-05      0.12      11      49 ..     917     960 ..     906     963 .. 0.86
   3 ?    0.9   0.0      0.18   4.6e+02      24      52 ..    1135    1163 ..    1131    1163 .. 0.91

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 1.4e-06
  Nup35_RRM_2  15 elVlehFasfGeIvkhyvp...kevsvmyvkfesekdaekAL 53 
                  + ++++F+++G+Iv++ +        +++v+fe+  da+ AL
   EEA20848.1 846 SQIRQFFRDCGPIVDIKFLpseHDLTTAVVEFETQEDAAAAL 887
                  56899**********9998666446799***********998 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 4.8e-05
  Nup35_RRM_2  11 telielVlehFasfGeIvkhyvp.....kevsvmyvkfesekda 49 
                  t++++ ++  F + GeIv+  +p       + + yv+f+s+++a
   EEA20848.1 917 TADEAFIRSLFSEAGEIVEVRFPslkynTHRRFCYVQFKSPDQA 960
                  5566788889*************99999889**********998 PP

  == domain 3  score: 0.9 bits;  conditional E-value: 0.18
  Nup35_RRM_2   24 fGeIvkhyvpkevsvmyvkfesekdaekA 52  
                   fG+ vk+  ++ +  ++v+f + k+a kA
   EEA20848.1 1135 FGPLVKIILRPDREGAIVEFVDIKAAGKA 1163
                   9*********************9999888 PP

>> RRM_3  RNA binding motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.2       1.4   3.7e+03      48      81 ..     424     457 ..     406     467 .. 0.64
   2 !   10.1   0.0   0.00025      0.65      10      67 ..     840     897 ..     833     908 .. 0.79
   3 ?    1.2   0.0      0.15   3.8e+02      17      55 ..     922     965 ..     906     983 .. 0.75
   4 !    5.0   0.0    0.0096        25      12      56 ..    1008    1057 ..    1000    1072 .. 0.73

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.4
                 HHHHHHHHHHHHC-B-CCTSSEEEEE--HHHHHH CS
       RRM_3  48 eeakkalekateaklkikdaevtlelLeGeeEke 81 
                  +a++ +e+ ++  l+ kd ++++ + +   E e
  EEA20848.1 424 YAARQDFEHKVQRALESKDRNLEWAVYSEYIEWE 457
                 3455556666666677777777777766555544 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00025
                 SSS--HHHHHHHCHCCS...-ECEEEE-TTSSEEEEEESSHHHHHHHHHHHHHC-B-CCTS CS
       RRM_3  10 nkelsredikellsklg...evayvdyekgdkegevrFkedeeakkalekateaklkikda 67 
                  +++  ++i+++++  g   ++++   e++ +++ v F+++e+a +al    +    i+ +
  EEA20848.1 840 PSDIIESQIRQFFRDCGpivDIKFLPSEHDLTTAVVEFETQEDAAAALTRDQKR---INGQ 897
                 5677889**********88889999999***************99988765544...4444 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.15
                 HHHHHCHCCS...-ECE..EEE-TTSSEEEEEESSHHHHHHHHH CS
       RRM_3  17 dikellsklg...evay..vdyekgdkegevrFkedeeakkale 55 
                  i+ l+s+ g   ev++    y+     ++v+Fk++++a +a +
  EEA20848.1 922 FIRSLFSEAGeivEVRFpsLKYNTHRRFCYVQFKSPDQAIAATK 965
                 5888999999666677755678888899********99876654 PP

  == domain 4  score: 5.0 bits;  conditional E-value: 0.0096
                  S--HHHHHHHCHCCS-ECEEEE...-TTSSE..EEEEESSHHHHHHHHHH CS
       RRM_3   12 elsredikellsklgevayvdy...ekgdke..gevrFkedeeakkalek 56  
                  +   +d+kel+sk+g+++ v      +g++   g + F ++eea +al  
  EEA20848.1 1008 DARENDLKELFSKYGTIETVRIpskVNGEHRgfGFIVFSKKEEATAALAM 1057
                  566789*********98888652225677763357999999999888755 PP

>> Lsm_interact  Lsm interaction motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.7   9.3e-05      0.24       2      17 ..    1255    1270 ..    1254    1270 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 9.3e-05
  Lsm_interact    2 astakPmSNDDFRKMF 17  
                    ++ ++++ NDDFR MF
    EEA20848.1 1255 TEQKPQKTNDDFRAMF 1270
                    67899********999 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0      0.76   1.9e+03      22      38 ..     474     490 ..     473     493 .. 0.88
   2 ?   -3.4   0.0         7   1.8e+04      24      38 ..     516     530 ..     513     534 .. 0.83
   3 ?    8.3   0.0    0.0018       4.7       6      40 ..     630     664 ..     625     665 .. 0.88
   4 ?   -2.5   1.7       5.2   1.3e+04       9      33 ..     752     766 ..     722     779 .. 0.57

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.76
      TPR_14  22 allrralalaPddaeaw 38 
                 al++ral ++P+d   w
  EEA20848.1 474 ALYQRALLRFPTDVPMW 490
                 589*********98877 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 7
      TPR_14  24 lrralalaPddaeaw 38 
                  +ra +++P++  +w
  EEA20848.1 516 IERATRHCPWSGSLW 530
                 689******998777 PP

  == domain 3  score: 8.3 bits;  conditional E-value: 0.0018
      TPR_14   6 alaeallalGdpdeAiallrralalaPddaeawll 40 
                  + ++l ++G +d A+++++ ++a+  ++ e+wl 
  EEA20848.1 630 IYTRYLSESGSWDSAREYYKGLIATRGNSYEFWLD 664
                 5668999**********************999985 PP

  == domain 4  score: -2.5 bits;  conditional E-value: 5.2
      TPR_14   9 eallalGdpdeAiallrralalaPd 33 
                 eal+++   +          ++a +
  EEA20848.1 752 EALERAAAQQ----------SAAAS 766
                 2222222222..........22333 PP

>> Spore_coat_CotO  Spore coat protein CotO
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7  11.7      0.02        51      14     111 ..     732     825 ..     731     851 .. 0.63

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.02
  Spore_coat_CotO  14 QpkykeaaikmqeivrtsfkeekkqaaakekkdeaeekkpekaveeeveqekkkeaaePaeqeeeekaeeeekkeeeeqkeeeeekqetveaek 107
                      Q  ++e++++m+ + r+++ke+  + aa++++ +a  ++ + a++e++  e    aa  a++ +  ++   e +e + +k+ +e++    ++++
       EEA20848.1 732 QEALVETQMAMKAVARRRQKEAL-ERAAAQQSAAASTEAAQVAAAESMGTEGDVAAAAAASKRK-REEDSLETTETPHKKARPETISS--DHKE 821
                      7778999*******999977777.5555666666777777778888865555554444443333.33334455566666666666665..4455 PP

  Spore_coat_CotO 108 Peqe 111
                      P++ 
       EEA20848.1 822 PAEL 825
                      5543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1408  (0.078532); expected 358.6 (0.02)
Passed bias filter:                      586  (0.0326845); expected 358.6 (0.02)
Passed Vit filter:                        76  (0.00423894); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 1.02u 0.38s 00:00:01.40 Elapsed: 00:00:00.54
# Mc/sec: 7055.01
//
Query:       EEA20849.1  [L=265]
Description: hypothetical protein PMAA_046680 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (265 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       670  (0.0373696); expected 358.6 (0.02)
Passed bias filter:                      546  (0.0304535); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 1825.07
//
Query:       EEA20850.1  [L=222]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    0.00048   20.4   5.7    0.00085   19.6   5.7    1.4  1  L_HMGIC_fpl    Lipoma HMGIC fusion partner-like protein
  ------ inclusion threshold ------
      0.048   13.6  10.6       0.15   12.0  10.6    1.8  1  Claudin_3      Tight junction protein, Claudin-like
      0.091   12.9   0.5       0.65   10.2   0.1    2.1  2  TMEM223        Transmembrane protein 223
       0.42    9.9   7.1       0.21   10.9   2.7    1.9  2  STE2           Fungal pheromone mating factor STE2 GPCR
        0.5   10.3   2.4        1.4    8.9   0.1    2.6  3  PDR_CDR        CDR ABC transporter
        2.2    7.7  13.0        2.6    7.4   9.0    2.2  2  ABC2_membrane  ABC-2 type transporter


Domain annotation for each model (and alignments):
>> L_HMGIC_fpl  Lipoma HMGIC fusion partner-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   5.7   2.9e-07   0.00085       7     158 ..      36     187 ..      32     203 .. 0.64

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 2.9e-07
  L_HMGIC_fpl   7 llslvaavlelvafvspeWlvgsee.sekagslglyerCk.....kesqevelecgryaldflaipssawkaaavlvalgilllllvlllslltlcrq 98 
                  ll l+a   ++++++ p+W+  ++e  + + s gl++rC+      e   + ++c++ +        s+w+ + +l+a +++l++l +++ +++l   
   EEA20850.1  36 LLFLIAYAFTILSIILPNWVSYNSEkPPLHYSYGLHRRCSsltdiCEPFPQYEDCHGED----RYFCSMWRSVGFLMAFAVVLMSLGIVAYVIILSGG 129
                  566778888899********986552677999********3322222222333333333....233567**************777666666666666 PP

  L_HMGIC_fpl  99 silkksvfkicallqlvaglllllglllyPlgWdseevrklCGeeaekyelgdCslgway 158
                  + l ++ + +++++ +++  + +++++l  +  d++e     G + +k + + C++ w +
   EEA20850.1 130 KKLRETGWGVLSTIIVLSVAVQVASMALVAYLFDNDERFF-IGWQLDK-SFAFCTVSWCI 187
                  6788888888888888887777777777777777766443.3444433.34556666543 PP

>> Claudin_3  Tight junction protein, Claudin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0  10.6     5e-05      0.15       8     153 ..      33     194 ..      20     202 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 5e-05
   Claudin_3   8 lgvl.vvisfilnivglftpaWiteest.........................kkeksiGivPfssteagwleaasimmyislalflvviliyivivrk 80 
                 l++l  +i+  ++i+++ +p+W++++s+                         + e+++G   + +   ++   ++++m ++     vv++++ ++++ 
  EEA20850.1  33 LTLLlFLIAYAFTILSIILPNWVSYNSEkpplhysyglhrrcssltdicepfpQYEDCHGEDRYFC---SMWRSVGFLMAFA-----VVLMSLGIVAYV 123
                 44455999********************9*999999888876666666666555556666555555...3444444444433.....344666677777 PP

   Claudin_3  81 vkkngysksvrklffliallslliviltviaviliavnvskfndsfndsslqLGYsawlsvisailslinvaL 153
                 +  +g  k   +   +++ + +l+v+ +v+++ l+a  ++ + ++f  +  qL  s+ ++ +s  +sl+ +a 
  EEA20850.1 124 IILSGGKKLRETGWGVLSTIIVLSVAVQVASMALVAYLFD-NDERFFIGW-QLDKSFAFCTVSWCISLFCAAT 194
                 777888888888999*********************9999.555666666.7888888888888887776554 PP

>> TMEM223  Transmembrane protein 223
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0      0.18   5.5e+02      57      82 ..      27      52 ..       9      54 .. 0.80
   2 ?   10.2   0.1   0.00022      0.65      61     104 ..      96     138 ..      83     159 .. 0.81

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.18
     TMEM223 57 nkkrvgltlicllvgvlilllgllfp 82
                ++  +gltl+++l+++++++l+++ p
  EEA20850.1 27 KTIVYGLTLLLFLIAYAFTILSIILP 52
                55668999999****99999998876 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.00022
     TMEM223  61 vgltlicllvgvlilllgllfplRsvkkvvllkggktveivTya 104
                 + + ++   vg+l++++++l++l  v +v++l ggk+++ +  +
  EEA20850.1  96 Y-FCSMWRSVGFLMAFAVVLMSLGIVAYVIILSGGKKLRETGWG 138
                 5.56677789**************************99765555 PP

>> STE2  Fungal pheromone mating factor STE2 GPCR
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.2     0.056   1.7e+02     147     181 ..      26      60 ..      21      78 .. 0.82
   2 ?   10.9   2.7     7e-05      0.21     106     205 ..      91     191 ..      70     198 .. 0.70

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.056
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XX CS
        STE2 147 lrvvltalsallalvtvgfrlalavlniraileae 181
                 +++++ +l++ll l++ +f++ +++l +   +++e
  EEA20850.1  26 TKTIVYGLTLLLFLIAYAFTILSIILPNWVSYNSE 60 
                 5788999999999******9999999887777544 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 7e-05
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXX..XX CS
        STE2 106 vsrsdlavsvaanvlsvllvalieasLvlQvrvvfstlpkllrvvltalsallalvtvgfrlalavlniraileaeetsssswleslslilfavs..In 202
                   +  + +s+  +v  ++ +a++ +sL + ++v++ +  k+lr +  ++ +++ +++v++++a++ l +  +  ++e     w  + s+++ +vs  I 
  EEA20850.1  91 HGEDRYFCSMWRSVGFLMAFAVVLMSLGIVAYVIILSGGKKLRETGWGVLSTIIVLSVAVQVASMALVAYLFD-NDERFFIGWQLDKSFAFCTVSwcIS 188
                 5566778888888999999****************666699999999999999999******99988655444.3333344444444444444441144 PP

                 XXX CS
        STE2 203 ffs 205
                 +f+
  EEA20850.1 189 LFC 191
                 455 PP

>> PDR_CDR  CDR ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.1      0.33   9.9e+02      50      63 ..      38      51 ..      28      63 .. 0.65
   2 ?    8.9   0.1   0.00047       1.4      45      71 ..      99     125 ..      91     134 .. 0.86
   3 ?   -2.1   0.0       1.2   3.6e+03      56      68 ..     185     198 ..     176     210 .. 0.60

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.33
     PDR_CDR 50 fgiliaflifflal 63
                f i +af+i+ ++l
  EEA20850.1 38 FLIAYAFTILSIIL 51
                45556666555544 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.00047
     PDR_CDR  45 hlwrnfgiliaflifflalyllateli 71 
                  +wr +g l+af+++ + l ++a  +i
  EEA20850.1  99 SMWRSVGFLMAFAVVLMSLGIVAYVII 125
                 58***************9999987655 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 1.2
     PDR_CDR  56 fli.fflalyllat 68 
                 ++i +f+a++++++
  EEA20850.1 185 WCIsLFCAATVVVA 198
                 33325666666554 PP

>> ABC2_membrane  ABC-2 type transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.1     0.049   1.5e+02     167     192 ..      32      58 ..      15      73 .. 0.61
   2 ?    7.4   9.0   0.00088       2.6      56     148 ..     104     195 ..      84     203 .. 0.80

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.049
  ABC2_membrane 167 lvllpllllsGffipidsm.pkwlqwi 192
                     ++l+l+l + +f  ++ + p+w+ + 
     EEA20850.1  32 GLTLLLFLIAYAFTILSIIlPNWVSYN 58 
                    344555555555555555555555555 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.00088
  ABC2_membrane  56 lffsvlflafsaltsvapvferergvlerelvsplyslsayvlakvlvelpvsllqalifllivyflvgldlsrfflflllllltalaasslg 148
                    ++f++ f ++++  ++ + +++  +  ++++ +++  ls++++ +v+v+++ ++l+a +f     f++g++l++ f f+ + ++++l++ +  
     EEA20850.1 104 VGFLMAFAVVLMSLGI-VAYVIILSGGKKLRETGWGVLSTIIVLSVAVQVASMALVAYLFDNDERFFIGWQLDKSFAFCTVSWCISLFCAATV 195
                    3445555554445555.66777777789999999999*************************999999*****77888888888888876654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (222 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       852  (0.0475208); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 1596.76
//
Query:       EEA20851.1  [L=173]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    0.00015   22.1   3.8    0.00049   20.4   3.6    1.7  1  L_HMGIC_fpl  Lipoma HMGIC fusion partner-like protein
  ------ inclusion threshold ------
      0.015   15.3   5.2      0.034   14.1   5.1    1.6  1  Claudin_3    Tight junction protein, Claudin-like
        0.1   12.5   0.2       0.88    9.5   0.0    2.3  2  PDR_CDR      CDR ABC transporter
       0.13   12.4   0.7       0.13   12.4   0.7    2.7  3  SPC12        Microsomal signal peptidase 12 kDa subunit (SPC1
       0.26   11.4   3.1       0.68   10.1   0.7    2.2  2  TMEM223      Transmembrane protein 223
        1.8    8.7   5.2        3.1    7.9   2.1    2.0  2  DHHC         DHHC palmitoyltransferase
        4.5    6.6   8.2       0.22   10.9   1.6    1.8  2  TMEM43       Transmembrane protein 43


Domain annotation for each model (and alignments):
>> L_HMGIC_fpl  Lipoma HMGIC fusion partner-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   3.6   1.9e-07   0.00049       7      96 ..      36     127 ..      32     164 .. 0.62

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 1.9e-07
  L_HMGIC_fpl   7 llslvaavlelvafvspeWlvgsee.sekagslglyerCk.....kesqevelecgryaldflaipssawkaaavlvalgilllllvlllslltlc 96 
                  ll l+a   ++++++ p+W+  ++e  + + s gl++rC+      e   + ++c++ +        s+w+ + +l+a +++l++l +++ +++l 
   EEA20851.1  36 LLFLIAYAFTILSIILPNWVSYNSEkPPLHYSYGLHRRCSsltdiCEPFPQYEDCHGEDR----YFCSMWRSVGFLMAFAVVLMSLGIVAYVIILS 127
                  566778888899********986552677999********33332222333334444443....33457999999999999995544444444443 PP

>> Claudin_3  Tight junction protein, Claudin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   5.1   1.3e-05     0.034       8     113 ..      33     162 ..      24     172 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 1.3e-05
   Claudin_3   8 lgvl.vvisfilnivglftpaWiteest.........................kkeksiGivPfssteagwleaasimmyislalflvviliyivivrk 80 
                 l++l  +i+  ++i+++ +p+W++++s+                         + e+++G   + +   ++   ++++m ++++l+ + i+ y++i   
  EEA20851.1  33 LTLLlFLIAYAFTILSIILPNWVSYNSEkpplhysyglhrrcssltdicepfpQYEDCHGEDRYFC---SMWRSVGFLMAFAVVLMSLGIVAYVIILSG 128
                 44455999**********************999999999998888888888888888888877777...688889999999999999988888888776 PP

   Claudin_3  81 vkk.ngysksvrklffliallslliviltviavi 113
                  kk +++   v + + ++++++ ++++ +v+++ 
  EEA20851.1 129 GKKlRETGWGVLSTIIVLSVAVQVASMALVVSIL 162
                 5553566667888888888888888877777765 PP

>> PDR_CDR  CDR ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.1      0.25   6.3e+02      50      63 ..      38      51 ..      27      65 .. 0.66
   2 ?    9.5   0.0   0.00034      0.88      45      71 ..      99     125 ..      88     135 .. 0.87

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.25
     PDR_CDR 50 fgiliaflifflal 63
                f i +af+i+ ++l
  EEA20851.1 38 FLIAYAFTILSIIL 51
                44555555555444 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00034
     PDR_CDR  45 hlwrnfgiliaflifflalyllateli 71 
                  +wr +g l+af+++ + l ++a  +i
  EEA20851.1  99 SMWRSVGFLMAFAVVLMSLGIVAYVII 125
                 58***************9999987655 PP

>> SPC12  Microsomal signal peptidase 12 kDa subunit (SPC12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.7   4.9e-05      0.13      36      63 ..      33      61 ..      21      66 .. 0.73
   2 ?   -0.2   1.0      0.43   1.1e+03      23      42 ..     104     123 ..      95     127 .. 0.55
   3 ?   -1.7   1.0       1.2   3.1e+03      26      33 ..     147     154 ..     136     165 .. 0.40

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 4.9e-05
       SPC12 36 ltlyillagvvltll.vvvPpWpfYnrnp 63
                ltl+++l+++++t+l +++P+W  Yn ++
  EEA20851.1 33 LTLLLFLIAYAFTILsIILPNWVSYNSEK 61
                567777777777765499*******9875 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.43
       SPC12  23 iafivGyitqdlkltlyill 42 
                 ++f++ +++  ++l +++++
  EEA20851.1 104 VGFLMAFAVVLMSLGIVAYV 123
                 55555555555555554444 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 1.2
       SPC12  26 ivGyitqd 33 
                  v   + +
  EEA20851.1 147 SVAVQVAS 154
                 22222222 PP

>> TMEM223  Transmembrane protein 223
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.1      0.14   3.5e+02      57      82 ..      27      52 ..       8      55 .. 0.81
   2 ?   10.1   0.7   0.00027      0.68      61     103 ..      96     137 ..      85     157 .. 0.81

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.14
     TMEM223 57 nkkrvgltlicllvgvlilllgllfp 82
                ++  +gltl+++l+++++++l+++ p
  EEA20851.1 27 KTIVYGLTLLLFLIAYAFTILSIILP 52
                566699999*******9999999876 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00027
     TMEM223  61 vgltlicllvgvlilllgllfplRsvkkvvllkggktveivTy 103
                 + + ++   vg+l++++++l++l  v +v++l ggk+++ +  
  EEA20851.1  96 Y-FCSMWRSVGFLMAFAVVLMSLGIVAYVIILSGGKKLRETGW 137
                 5.56677789**************************9976555 PP

>> DHHC  DHHC palmitoyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.1     0.081   2.1e+02      57      71 ..      35      49 ..      12      78 .. 0.56
   2 ?    7.9   2.1    0.0012       3.1      49     121 ..      95     170 ..      90     173 .] 0.58

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.081
        DHHC 57 ylllllilalvllli 71
                 ll+l+++a+++l+i
  EEA20851.1 35 LLLFLIAYAFTILSI 49
                111222222222222 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0012
        DHHC  49 kyFllfllylllllilalv...lllialvklveeekkseflavtllkkllsilllvlsllfllllgllllfhlyli 121
                 +yF+ +  ++ +l+++a+v   l ++a+v +++  kk +++ +  l++++++ ++v+ + ++l++++l+l   +++
  EEA20851.1  95 RYFCSMWRSVGFLMAFAVVlmsLGIVAYVIILSGGKKLRETGWGVLSTIIVLSVAVQVASMALVVSILFLLDNMNV 170
                 6775544444444444444111334444444455555555555555667788888888888888888888776655 PP

>> TMEM43  Transmembrane protein 43
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.6      0.32   8.1e+02     221     247 ..      28      55 ..      19      58 .. 0.59
   2 ?   10.9   1.6   8.6e-05      0.22     181     247 ..      93     158 ..      86     160 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.32
      TMEM43 221 lvglglalvalllslslsllviala.wl 247
                  +  gl l+ +l++ ++++l i l+ w+
  EEA20851.1  28 TIVYGLTLLLFLIAYAFTILSIILPnWV 55 
                 4445666667777777777666553255 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 8.6e-05
      TMEM43 181 enklltwllRllGfllmflglllllsplsvlvslipllgelvglglalvalllslslsllvialawl 247
                 e + +  ++R +Gfl+ f  +l+ l ++++++ l    ++l ++g ++++ ++ ls+++ v ++a +
  EEA20851.1  93 EDRYFCSMWRSVGFLMAFAVVLMSLGIVAYVIILSGG-KKLRETGWGVLSTIIVLSVAVQVASMALV 158
                 66778889***********999999999999997777.9********99999999999999888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (173 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       911  (0.0508115); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 1169.59
//
Query:       EEA20852.1  [L=660]
Description: hypothetical pathogenicity factor [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.035   11.6   0.7      0.052   11.0   0.7    1.2  1  HHV6-IE   Human herpesvirus 6 immediate early protein


Domain annotation for each model (and alignments):
>> HHV6-IE  Human herpesvirus 6 immediate early protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.7   2.9e-06     0.052     804     880 ..     212     291 ..     200     304 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 2.9e-06
     HHV6-IE 804 esdsesssesddctsedkylhlsdydkvinn..ghcqskgfpspvftipirs.mqgtgdikskfvpkknwlwfmkkthkv 880
                 ++ +  +se +  +   k +hl +y ++ nn  g c+ +  p  + +  i s + g ++  ++ +p   w+w+ +k ++ 
  EEA20852.1 212 QNRTTVASEDKKESESPKVIHLCQYTDMENNvwGPCNENPNPEDINARKIVShIFGRNKKPTQNIPDELWIWYCRKHYQR 291
                 4455556666665666799***********9556677777777788888776356888888999************9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (660 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       918  (0.051202); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.43
# Mc/sec: 4562.88
//
Query:       EEA20853.1  [L=899]
Description: conserved serine proline-rich protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-14   54.4   0.0    2.1e-14   53.7   0.0    1.4  1  C2        C2 domain


Domain annotation for each model (and alignments):
>> C2  C2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.7   0.0   1.2e-18   2.1e-14       2     103 .]      31     133 ..      30     133 .. 0.89

  Alignments for each domain:
  == domain 1  score: 53.7 bits;  conditional E-value: 1.2e-18
                 EEEEEEEEEESSSSSSTTSSCEEEEEEEEECEEEEEE-SC.SSSSSSEEEEEEEEEESC.HTTSEEEEEEEEECSSSTEEEEEEEEEEGHH..HHTTHH CS
          C2   2 klevtvieAknLpnkdkkgssdpyvkvsldgkqkakTrvi.knslnPvWnekftfevae.leeakLeveVfdndrlskddfiGkveiplst..llsgee 96 
                 +l v   +AknLpn++  g+ +pyv + l gk+ +kT++  +    P+W++++++ v+e +   +L+v+Vf++d+  + d+iG++ ++ls+  +  g +
  EEA20853.1  31 TLVVIFDRAKNLPNRKTIGKQNPYVAARL-GKEAKKTETDmRGGQTPRWDQEIRYTVHEsPDYLQLKVSVFNDDK--RTDLIGETWVDLSSviIPGGGQ 126
                 67788889*******99************.7777777765477778*************9999999*****9998..9999**********99889999 PP

                 HHEEEEH CS
          C2  97 aegwypl 103
                  + w++l
  EEA20853.1 127 SDSWHEL 133
                 9999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (899 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       465  (0.0259356); expected 358.6 (0.02)
Passed bias filter:                      181  (0.0100954); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.69u 0.29s 00:00:00.98 Elapsed: 00:00:00.48
# Mc/sec: 5649.86
//
Query:       EEA20854.1  [L=142]
Description: hypothetical protein PMAA_046720 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.2e-08   33.2   0.0    8.5e-08   32.8   0.0    1.2  1  SnoaL_2   SnoaL-like domain
    1.8e-05   25.1   0.0    2.3e-05   24.7   0.0    1.1  1  DUF4440   Domain of unknown function (DUF4440)
    3.7e-05   24.3   0.0      5e-05   23.9   0.0    1.1  1  NTF2      Nuclear transport factor 2 (NTF2) domain
  ------ inclusion threshold ------
      0.017   15.2   0.0      0.019   15.1   0.0    1.1  1  LEH       Limonene-1,2-epoxide hydrolase catalytic domain
      0.041   13.7   0.0      0.051   13.4   0.0    1.3  1  SnoaL     SnoaL-like polyketide cyclase
       0.15   10.2   0.0       0.19    9.8   0.0    1.0  1  RHD3      Root hair defective 3 GTP-binding protein (RHD3)


Domain annotation for each model (and alignments):
>> SnoaL_2  SnoaL-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.8   0.0   2.9e-11   8.5e-08       2      92 ..      15     109 ..       7     118 .. 0.86

  Alignments for each domain:
  == domain 1  score: 32.8 bits;  conditional E-value: 2.9e-11
                 HHHHHHHHTTCHH.HHHHTEEEEEEEEET.TSEEESHHHHHHHHHHHHHHEEEEEEEEEEEEEETTEEEEEEEEEEE..EETTSSEEEEEEEEEE CS
     SnoaL_2   2 raflaalnagdld.alaalfapdvvwedp.ggelrGreairaffralfaafpdlrfeihdvvadgdrvavewtvtgt..ipatgrgvtvrgvdvf 92 
                 ++f   ++a d+  a+  ++++d+v++ +  ++++G+  i +ff + f +++ ++++i++v +  dr+  e ++++     ++ ++++v+g +vf
  EEA20854.1  15 EDFHKHMDAMDPNlAIPKFYTDDCVLRFAkNPAISGKSSIIDFFNSQFPHLESMKHTIKHVDVLPDRIYQEADIRYVvkGDPERKEIPVTGLAVF 109
                 67778888889875789************7777**************************************888877556777777777777776 PP

>> DUF4440  Domain of unknown function (DUF4440)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.0   7.8e-09   2.3e-05       6      98 ..      15     109 ..      11     116 .. 0.87

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 7.8e-09
                 HHHHHHHHCT-HH.HHHHCEEEEEEEE-TTS-EE.EHHHHHHHHHCCHCEEEEEEEEEEEEEEETTEEEEEEEEEEEECCTTEEEEEEEEEEEEE CS
     DUF4440   6 ealeeafvagdae.alaallapdavlvgpsgtvl.dkeellealeagfaagrslelteeevrvlgdlAvvtgrytfegrgdgepvegrgrftsvw 98 
                 e++ + + a d+  a+ +++++d+vl  ++ + + +k ++++ + ++f + +s++ t+ +v+vl+d  ++ +  ++ ++gd e  e   + ++v+
  EEA20854.1  15 EDFHKHMDAMDPNlAIPKFYTDDCVLRFAKNPAIsGKSSIIDFFNSQFPHLESMKHTIKHVDVLPDRIYQEADIRYVVKGDPERKEIPVTGLAVF 109
                 6778888999999999**************998759***************************************99999988777666666666 PP

>> NTF2  Nuclear transport factor 2 (NTF2) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.0   1.7e-08     5e-05       9      86 ..      17      96 ..      10     104 .. 0.76

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 1.7e-08
                HHHHHHHHGGG.GGGGGEEEEEEEEEETTEEEEESHHHHHHHHHHS.SCSCE.EEEEEEEEEEETSEGGGCEEEEEEEEEE CS
        NTF2  9 YYaaldagdre.gllalyaadaslltpegsspvkgreaIteffrsl.pftri.elkittvdaqpdeaslstgvlvmvtGel 86
                +   +da d++ ++ ++y +d+++l +  + +++g+ +I +ff+s  p+ ++ +++i +vd+ pd    + ++  +v+G+ 
  EEA20854.1 17 FHKHMDAMDPNlAIPKFY-TDDCVLRFAKNPAISGKSSIIDFFNSQfPHLESmKHTIKHVDVLPDRIYQEADIRYVVKGDP 96
                556677777772356888.666677776666************9861555577***********77777888998888876 PP

>> LEH  Limonene-1,2-epoxide hydrolase catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.1   0.0   6.4e-06     0.019       3     117 ..      10     128 ..       8     136 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 6.4e-06
                 HHHHHHHHHHHHHHT-HHHHHHHEEEEE.EEEETTTEEEE-HHHHHHHHHTT.TTT-EEEEEEEEEEEETTEEEEEEEEEEEE..TTEEEEEEEEE..E CS
         LEH   3 pirvVeaFlaalqeddydaavrrlatdlevyeneglstihGraeaiallerlsadilavevkilriaadgsaVltERlDrliladGplivqltvmG..v 99 
                 +i   e F + ++  d + a+ ++ td+ v      ++i G++  i +++  +    +++  i  +     +++ E   r++++  p++ +++v+G  v
  EEA20854.1  10 AIAWLEDFHKHMDAMDPNLAIPKFYTDDCVLRFAKNPAISGKSSIIDFFNSQFPHLESMKHTIKHVDVLPDRIYQEADIRYVVKGDPERKEIPVTGlaV 108
                 6777899*******************999************************************************99*****99*********9444 PP

                 E..EEETTEEEEEEEE--HH CS
         LEH 100 f..eVedgrivlWRdYfDvn 117
                 f  +  d+++  +  Y D  
  EEA20854.1 109 FgrKLGDEKMSFFTVYLDPT 128
                 54456677777666666655 PP

>> SnoaL  SnoaL-like polyketide cyclase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   1.7e-05     0.051      18      75 ..      29      86 ..       8     123 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 1.7e-05
                HHHGTEEEEEEETCCTTTCECHHHHHHHHHHHHHHHCTTCEEEEEEEEEETTEEEEEE CS
       SnoaL 18 aldelvaedvvdhnpeeeparGlegfrafveelfkafPDlkvevedlvaegdkvaarl 75
                a+ +++++d+v + +++    G++++ +f+++ f  +  +k++++++ +  d+++ ++
  EEA20854.1 29 AIPKFYTDDCVLRFAKNPAISGKSSIIDFFNSQFPHLESMKHTIKHVDVLPDRIYQEA 86
                6899******************************************999999988655 PP

>> RHD3  Root hair defective 3 GTP-binding protein (RHD3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0   6.4e-05      0.19     161     231 ..      46     112 ..      41     117 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 6.4e-05
                 -GGGTT--HHHHEEEEEEEEE-TTT-HHHHHHHHHHHHHHHTTS....--S--GG.GS-SS-HHHHHHHHHH CS
        RHD3 161 PegleessledfFdvefvaLshkelkeeqFkeevkkLrerfveskeiengvfkpe.yhkriPadgfslyaeq 231
                 P+   +ss+ dfF+ +f  L +     ++  ++v+ L +r+ +  +   +v+k++  +k+iP+ g++++ ++
  EEA20854.1  46 PAISGKSSIIDFFNSQFPHLESM----KHTIKHVDVLPDRIYQEAD-IRYVVKGDpERKEIPVTGLAVFGRK 112
                 7777899**********988775....455789**********855.6788888746899******998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (142 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       344  (0.0191868); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.46
# Mc/sec: 923.98
//
Query:       EEA20855.1  [L=540]
Description: small nucleolar ribonucleoprotein complex subunit Utp15, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.5e-53  179.2   0.1      1e-52  177.7   0.3    1.7  2  UTP15_C      UTP15 C terminal
    6.6e-20   71.1   1.8    0.00086   20.1   0.0    6.4  7  WD40         WD domain, G-beta repeat
    4.7e-09   36.4   0.1     0.0034   17.6   0.0    4.7  6  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
    0.00022   20.6   0.2        0.2   10.9   0.1    2.3  2  RAB3GAP2_N   Rab3 GTPase-activating protein regulatory subuni
     0.0036   16.9   0.9       0.03   13.9   0.4    2.3  2  PQQ_2        PQQ-like domain
  ------ inclusion threshold ------
      0.041   13.2   0.0       0.22   10.8   0.0    1.7  2  CPSF_A       CPSF A subunit region


Domain annotation for each model (and alignments):
>> UTP15_C  UTP15 C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       1.4   4.2e+03      26      41 ..     221     236 ..     215     244 .. 0.81
   2 !  177.7   0.3   3.5e-56     1e-52       1     147 []     391     537 ..     391     537 .. 0.96

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1.4
     UTP15_C  26 LrkfryskALdavlek 41 
                   +f++s+A+ +vl  
  EEA20855.1 221 VMTFQMSAAIECVLPM 236
                 5689*********987 PP

  == domain 2  score: 177.7 bits;  conditional E-value: 3.5e-56
     UTP15_C   1 dykgeeadivieek...kkkklkkydklLrkfryskALdavlekkvekspevvvtlleeLrhRgalraALagrdeeslepiLkfllkhitdpryvsllv 96 
                 d+ ge++di+i+++   k+kk+++++ +Lr+ rys+AL++vl     ++++  +tl+++LrhR+alr+AL +rde++l+piLk+++k+i++pr v+++v
  EEA20855.1 391 DFLGEGVDIIIQGQdtkKRKKESDWESDLRHARYSEALNRVLAG---TDKTAQLTLITALRHRSALRTALMNRDEVTLQPILKWVYKYISEPRLVNICV 486
                 5789*******8444559**************************...78************************************************** PP

     UTP15_C  97 dvanvlldlyseklgqseeldelvkrLkrkvreevelakellelkGmlell 147
                 +v +++ld+ys +lgqs+ +d ++ +L+++vreev++a++++++kGml++l
  EEA20855.1 487 EVGMNILDIYSGNLGQSADVDAQIIKLHKRVREEVDRAQQAWQTKGMLDML 537
                 **************************************************8 PP

>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0     0.051   1.5e+02      18      38 .]     104     124 ..      75     124 .. 0.82
   2 !   18.8   0.2   7.2e-07    0.0022       4      38 .]     131     167 ..     128     167 .. 0.73
   3 !   20.1   0.0   2.9e-07   0.00086       4      38 .]     174     213 ..     171     213 .. 0.76
   4 ?    1.2   0.0      0.27   8.2e+02      13      34 ..     230     250 ..     219     253 .. 0.81
   5 !   18.9   0.0   6.6e-07     0.002       1      38 []     258     296 ..     258     296 .. 0.95
   6 ?    0.5   0.0      0.45   1.3e+03      12      34 ..     311     329 ..     302     331 .. 0.75
   7 ?   -3.6   0.0         6   1.8e+04      24      33 ..     430     438 ..     421     439 .. 0.71

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.051
                 EETTSSEEEEEETTSEEEEEE CS
        WD40  18 fspdgawlasGsdDgtvriWd 38 
                   pdg+ +a G+d gt+ ++d
  EEA20855.1 104 IRPDGRIIAVGDDTGTIQVFD 124
                 68*********9999999987 PP

  == domain 2  score: 18.8 bits;  conditional E-value: 7.2e-07
                 EEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 
                 l+t++ H ++v+  +fsp+ +  l+s sdD+tvr+W+
  EEA20855.1 131 LKTWKDHkQPVWVTKFSPSDPTtLLSTSDDRTVRLWS 167
                 789999*7776555566666666567788*******5 PP

  == domain 3  score: 20.1 bits;  conditional E-value: 2.9e-07
                 EEEEESS.SSEEEEEEETTSSE....EEEEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgaw....lasGsdDgtvriWd 38 
                  rt+tGH + v+s af p +      ++sGs+D+tvr+Wd
  EEA20855.1 174 ERTFTGHtDYVRSGAFLPGSMAsagmVVSGSYDKTVRLWD 213
                 589****555987755555555677689***********9 PP

  == domain 4  score: 1.2 bits;  conditional E-value: 0.27
                 EEEEEEETTSSEEEEEETTSEE CS
        WD40  13 vtslafspdgawlasGsdDgtv 34 
                 + ++   p+g+ ++++  D+ +
  EEA20855.1 230 IECVLPMPSGTTVLAAA-DNQI 250
                 99999*******99988.8876 PP

  == domain 5  score: 18.9 bits;  conditional E-value: 6.6e-07
                 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 g++l+ ++ H + vtsl+  + g  ++sG  Dg+++++d
  EEA20855.1 258 GKPLHMIKSHqKTVTSLSLASKGERVVSGALDGHLKVFD 296
                 689*******999****************99******98 PP

  == domain 6  score: 0.5 bits;  conditional E-value: 0.45
                 SEEEEEEETTSSEEEEEET..TSEE CS
        WD40  12 svtslafspdgawlasGsd..Dgtv 34 
                 ++ sl      + l+sGs+  D+++
  EEA20855.1 311 PILSL------RVLTSGSEreDKHI 329
                 47788......88999*94459998 PP

  == domain 7  score: -3.6 bits;  conditional E-value: 6
                 EEEEEETTSE CS
        WD40  24 wlasGsdDgt 33 
                  +++G+ D+t
  EEA20855.1 430 RVLAGT-DKT 438
                 355799.987 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0       1.3     4e+03      39      65 ..      21      48 ..      15      52 .. 0.72
   2 !   17.6   0.0   1.1e-06    0.0034      37      81 ..      95     139 ..      71     149 .. 0.79
   3 !   11.8   0.0   7.6e-05      0.23      22      88 ..     214     275 ..     203     279 .. 0.78
   4 !    9.6   0.0   0.00037       1.1      56      88 ..     244     275 ..     242     315 .. 0.78
   5 ?   -3.0   0.0       3.1   9.1e+03      50      68 ..     326     344 ..     323     360 .. 0.63
   6 ?   -2.0   0.0       1.6   4.7e+03      59      86 ..     487     512 ..     477     515 .. 0.74

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 1.3
  ANAPC4_WD40 39 sevrsLaWkp.dgklLavaysdgevrll 65
                  + ++L W+  ++ lL+ + s++ ++l+
   EEA20855.1 21 LTTEQLYWRSfKNPLLVSSPSNNPINLI 48
                 5667899986255677777888888887 PP

  == domain 2  score: 17.6 bits;  conditional E-value: 1.1e-06
  ANAPC4_WD40  37 edsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvkse 81 
                   d + r+   +pdg+++av+ + g+++++d++s  ++++++ +++
   EEA20855.1  95 FDDTARGTDIRPDGRIIAVGDDTGTIQVFDVNSRAILKTWKDHKQ 139
                  46667788889****************************998876 PP

  == domain 3  score: 11.8 bits;  conditional E-value: 7.6e-05
  ANAPC4_WD40  22 fRlngqrvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclg 88 
                   R++g+ v+t+   + +  ++++   p+g+  + a +d+++ +ld+  gk +h ++ +++ +vt+l+
   EEA20855.1 214 PRVDGRAVMTF---QMSAAIECVLPMPSGTT-VLAAADNQIAVLDVVGGKPLHMIKSHQK-TVTSLS 275
                  57777777777...66777777777777776.45779*********************99.599986 PP

  == domain 4  score: 9.6 bits;  conditional E-value: 0.00037
  ANAPC4_WD40  56 aysdgevrlldaesgkvvhslsvksekavtclg 88 
                  a +d+++ +ld+  gk +h ++ +++ +vt+l+
   EEA20855.1 244 AAADNQIAVLDVVGGKPLHMIKSHQK-TVTSLS 275
                  66788888888888888888888877.477765 PP

  == domain 5  score: -3.0 bits;  conditional E-value: 3.1
  ANAPC4_WD40  50 gklLavaysdgevrlldae 68 
                  +k +av+++ g +++    
   EEA20855.1 326 DKHIAVGMQSGLLSIKTRL 344
                  5667777777766654444 PP

  == domain 6  score: -2.0 bits;  conditional E-value: 1.6
  ANAPC4_WD40  59 dgevrlldaesgkvvhslsvksekavtc 86 
                  +  +++ld++sg++ +s +v+++  + +
   EEA20855.1 487 EVGMNILDIYSGNLGQSADVDAQ--IIK 512
                  55678999999999998888776..555 PP

>> RAB3GAP2_N  Rab3 GTPase-activating protein regulatory subunit N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.9   0.1   6.7e-05       0.2     315     346 ..     104     135 ..      68     139 .. 0.88
   2 !    7.4   0.0   0.00078       2.3      77     138 ..     281     342 ..     260     381 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 6.7e-05
  RAB3GAP2_N 315 lsPsgrlaavtDsLgRVlLlDvqagvvvRlWK 346
                 + P+gr+ av D+ g + ++Dv+ + +++ WK
  EEA20855.1 104 IRPDGRIIAVGDDTGTIQVFDVNSRAILKTWK 135
                 67*****************************9 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.00078
  RAB3GAP2_N  77 tviavGlssGylrfytengelLlsqllheepvlkikcvssqekeeseelsilypkaivvidg 138
                   ++ G  +G+l++++ +g  ++     ++p+l++++++s+ ++e++ +++ +++ +  i+ 
  EEA20855.1 281 ERVVSGALDGHLKVFDTTGWSVVAGSKFPSPILSLRVLTSGSEREDKHIAVGMQSGLLSIKT 342
                 458899******************************658889999999***99999888764 PP

>> PQQ_2  PQQ-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0     0.064   1.9e+02     171     235 ..      63     132 ..      38     135 .. 0.70
   2 !   13.9   0.4     1e-05      0.03      16     138 ..     165     296 ..     116     353 .. 0.67

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.064
       PQQ_2 171 vaeg.tVyassgqgrllaldlatgr..rlw.ske.issinglpildgdllyvvsa.gelialdratGavlW 235
                  a+  +V+ ++   r+  + ++t +  +   ++   +++ +   +dg+++ v+++ g++  +d+++ a+l+
  EEA20855.1  63 AAQPpDVFTVTTGARVQIYSVRTRKllK-TiTRFdDTARGTDIRPDGRIIAVGDDtGTIQVFDVNSRAILK 132
                 4444678888888876666888888432.334443444444478899999999966999999998877765 PP

  == domain 2  score: 13.9 bits;  conditional E-value: 1e-05
       PQQ_2  16 lWrvdlarp................lgggvsravlsggtlfvatgggrlvalda.atGkvlWettlegpvvgaplvaegrvvvvasdgqlialdaedGk 97 
                 lW++    p                +g+ + +   s+g ++++++  ++  +d+  +G+ + +++ ++ +     +  g +v++a+d+q++ ld   Gk
  EEA20855.1 165 LWSL----PsessertftghtdyvrSGAFLPGSMASAGMVVSGSYDKTVRLWDPrVDGRAVMTFQMSAAIECVLPMPSGTTVLAAADNQIAVLDVVGGK 259
                 3444....022223333344444445555555566999999999999999999845999999999999999997777778889999************* PP

       PQQ_2  98 rlWstqqrseepae..lrssaspavagdtvvvgessgklvald 138
                  l+ ++++++  ++  l+s+      g++vv g  +g l ++d
  EEA20855.1 260 PLHMIKSHQKTVTSlsLASK------GERVVSGALDGHLKVFD 296
                 *9998777732222224444......44444444444444444 PP

>> CPSF_A  CPSF A subunit region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   7.5e-05      0.22     105     210 ..      72     174 ..      64     196 .. 0.88
   2 ?   -1.2   0.0      0.33   9.9e+02      92     147 ..     229     286 ..     219     289 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 7.5e-05
                 EE-SSEEEEEEE-TTS-EEEEEEEE-SS-EEEEEEETTEEEEEESSS-EEEEEE-SSS--EEEEEEESS---EEEEEEE--SSSEEEEEETTSEEEEEE CS
      CPSF_A 105 vgvgqkvrvydlgedktLlrkafldtqlyvvslkvlgnriivgDlmkSvtfveydeenyklilfardtqkrwvtaaeflvdgedtvlvaDkfgnlfvlr 203
                 v  g  v +y + ++k L    ++d +   +++   g +i+vgD    ++++ +++    l++  ++ q++wvt+     d  +t+l + +++ + +  
  EEA20855.1  72 VTTGARVQIYSVRTRKLLKTITRFDDTARGTDIRPDGRIIAVGDDTGTIQVFDVNSRAI-LKTWKDHKQPVWVTKFSPS-DP-TTLLSTSDDRTVRLWS 167
                 67788999********4445567777779******************************.***************9999.88.8999999999999988 PP

                 --TTSGG CS
      CPSF_A 204 ydpease 210
                 ++ e se
  EEA20855.1 168 LPSESSE 174
                 8877665 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.33
                 ----EEEE.TTE.EEEE-SSEEEEEEE-TTS-EEEEEEEE-SS-EEEEEEETTEEEEE CS
      CPSF_A  92 avtalaef.qGr.llvgvgqkvrvydlgedktLlrkafldtqlyvvslkvlgnriivg 147
                 a+ ++ ++ +G  +l++  +++ v d+   k L    ++++++  +sl ++g+r++ g
  EEA20855.1 229 AIECVLPMpSGTtVLAAADNQIAVLDVVGGKPLHMIKSHQKTVTSLSLASKGERVVSG 286
                 5666666665555899999999999988888899999999999999999999988865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (540 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       893  (0.0498076); expected 358.6 (0.02)
Passed bias filter:                      583  (0.0325172); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.82u 0.38s 00:00:01.20 Elapsed: 00:00:00.59
# Mc/sec: 2749.09
//
Query:       EEA20856.1  [L=753]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.3e-26   93.3   0.0    2.8e-26   92.1   0.0    1.6  1  Fungal_trans    Fungal specific transcription factor domain
    4.8e-06   26.6   9.0    9.9e-06   25.6   9.0    1.6  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
       0.04   13.5   0.0       0.13   11.8   0.0    1.7  2  DAPG_hydrolase  DAPG hydrolase PhiG domain
        2.9    7.3   9.5         77    2.6  12.7    1.6  2  CAP_N           Adenylate cyclase associated (CAP) N terminal
        4.5    7.1  11.3        7.2    6.5  11.3    1.2  1  TFIIA           Transcription factor IIA, alpha/beta subunit


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.1   0.0   7.9e-30   2.8e-26       2     233 ..     199     411 ..     198     454 .. 0.85

  Alignments for each domain:
  == domain 1  score: 92.1 bits;  conditional E-value: 7.9e-30
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLl 98 
                     +f++fhp+fpi+++ +++++       + +  splll ++l +Ga++++ e+ + +  + +    + +f+ r + ++  d+  +++sl  lq+ +
    EEA20856.1 199 RAYFEWFHPCFPIVDRVDISKSC------NDKTISPLLLQSMLFIGASLCSIEALQASGFRDR-YETKFHFYDRGKEIF--DADCETDSLSKLQAVF 286
                   67**************5555555......5555********************9998555554.447888889******..888888889******* PP

  Fungal_trans  99 llelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddlwes 195
                   ll+++ +t +  +   +++g a++la++ gLh  ++ +       l ++e+  r+R++w+ ++ D ++a  +G pp ++d++ ++p+ ++ d ++e+
    EEA20856.1 287 LLSFWRSTPGHEKDTRYWLGAAISLAQTGGLHMLSKLSL------LKPKEKSVRKRIFWSLYIRDQQVAAAYGLPPRIRDEDCDIPMLDETD-FDEA 376
                   *************************************99......99999**************************77*********98888.7777 PP

  Fungal_trans 196 ddaseetlvetklsneeksrkiasfllaLkkilskiag 233
                    ++ +    ++   +++ + +   ++++ +++l ++++
    EEA20856.1 377 GFVGNRVIFGI---QRPEHISYIIQMVRAARLLREVVS 411
                   77666666663...466666666666666666666665 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   9.0   2.7e-09   9.9e-06       1      36 [.      17      52 ..      17      56 .. 0.90

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 2.7e-09
                SS-HHHHHCT---ST..SSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus  1 haCdnCrkkKvKCda..kkPaCsnCkklnleCtfyses 36
                +aC++C  ++vKC+   k+P C nC+ ++++C+ +  s
  EEA20856.1 17 RACITCNARRVKCNVveKQP-CDNCRISGSHCE-IGVS 52
                69**************9***.***********9.6555 PP

>> DAPG_hydrolase  DAPG hydrolase PhiG domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   3.5e-05      0.13     140     201 ..     275     337 ..     263     347 .. 0.81
   2 ?   -2.3   0.0      0.71   2.5e+03     143     160 ..     507     524 ..     442     582 .. 0.53

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3.5e-05
  DAPG_hydrolase 140 glgeepelklalmvHlvretegGlelrSrfwlgerv..arvaglekaaklvkalsegeavleel 201
                     ++ + ++l++  +++++r t+ G e  +r+wlg ++  a++ gl+  +kl   ++++++v++++
      EEA20856.1 275 ETDSLSKLQAVFLLSFWRSTP-GHEKDTRYWLGAAIslAQTGGLHMLSKLSLLKPKEKSVRKRI 337
                     55566789999********98.9*************8888888888888888888887777765 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 0.71
  DAPG_hydrolase 143 eepelklalmvHlvrete 160
                      + +l  + mvH++ ++ 
      EEA20856.1 507 LSHNLIEHGMVHIITNIF 524
                     222333344555555444 PP

>> CAP_N  Adenylate cyclase associated (CAP) N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0       1.2   4.3e+03     173     216 ..     374     415 ..     371     425 .. 0.81
   2 ?    2.6  12.7     0.022        77     233     275 ..     648     687 ..     624     699 .. 0.52

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 1.2
                 HHHHHHHHHHHHHHTTT-HHHHHHHHHHHHHHHHHHHHHHHHST CS
       CAP_N 173 daaqFYtNrVlkeykekdkkhveWvksflqilkeLqaYvkeyht 216
                 d a F +NrV+   +   ++h+ ++ ++++  + L++ v   + 
  EEA20856.1 374 DEAGFVGNRVIFGIQR--PEHISYIIQMVRAARLLREVVSASYL 415
                 6788999**9987765..57999999999999888888877665 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.022
                 .......SSC--XXXXXXX.....XXXXXXXX.....XXXXXXXXXXXX CS
       CAP_N 233 k.....aaaaaasaaaaggppp.PpPpPppasvfeeesaaasasaaagg 275
                 +     + +++a ++a++  +p P+PpPpp++ +++         ++++
  EEA20856.1 648 AvevspQPQPPAIQPAQQLEQPqPQPPPPPPQQQQQ---------QQQQ 687
                 233433333333333333333336666665543222.........2222 PP

>> TFIIA  Transcription factor IIA, alpha/beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5  11.3     0.002       7.2     152     230 ..     623     698 ..     577     722 .. 0.42

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.002
       TFIIA 152 qqiaaqplqqvvqqsqgsaaqssvaalqaqsqqaqalaepqqqlekqqqqqqqqqqqqqqqqvqqqqqeesqqaqqasq 230
                 ++  ++ l +++    +   +s+vaa++ ++q +  +++p qqle   q+q q++ +  qqq+qqqqq e+  +++++q
  EEA20856.1 623 TNSPSEFLRNTHVLPDSTKPASAVAAVEVSPQPQPPAIQPAQQLE---QPQPQPPPPPPQQQQQQQQQIEEVLNEEQPQ 698
                 333333333332222223333344444444344445566666644...2233333333333222222222222222212 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (753 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       899  (0.0501422); expected 358.6 (0.02)
Passed bias filter:                      532  (0.0296726); expected 358.6 (0.02)
Passed Vit filter:                        74  (0.00412739); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.85u 0.38s 00:00:01.23 Elapsed: 00:00:00.56
# Mc/sec: 4037.89
//
Query:       EEA20857.1  [L=446]
Description: hypothetical protein PMAA_046750 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
      0.048   13.4   0.2       0.39   10.5   0.1    2.6  2  Arg_repressor  Arginine repressor, DNA binding domain


Domain annotation for each model (and alignments):
>> Arg_repressor  Arginine repressor, DNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.1   2.2e-05      0.39      10      41 ..      38      68 ..      31      86 .. 0.80
   2 ?   -1.3   0.0      0.11   1.9e+03      16      34 ..     313     331 ..     305     332 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 2.2e-05
                   HHHHHHHS---SHHHHHHHHHTTT----HHHH CS
  Arg_repressor 10 ikkiikeekissQkelvelLkeeGidvtQatv 41
                   ik++  ++ ++  +e++ +L+ +Gi++ Q+t+
     EEA20857.1 38 IKELYFKQGLR-DHEIIHALETNGIKISQSTL 68
                   55555555554.479****************8 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.11
                    HS---SHHHHHHHHHTTT- CS
  Arg_repressor  16 eekissQkelvelLkeeGi 34 
                    +++is Q ++   L e+Gi
     EEA20857.1 313 NHSISGQSNVLYHLLEDGI 331
                    6889999999999999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (446 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       587  (0.0327403); expected 358.6 (0.02)
Passed bias filter:                      416  (0.0232026); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.49
# Mc/sec: 2732.58
//
Query:       EEA20858.1  [L=177]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (177 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      270  (0.0150594); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.37u 0.27s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 1300.89
//
Query:       EEA20859.1  [L=329]
Description: phytanoyl-CoA dioxygenase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.2e-43  148.1   0.0    5.6e-43  147.7   0.0    1.2  1  PhyH            Phytanoyl-CoA dioxygenase (PhyH)
  ------ inclusion threshold ------
       0.03   14.7   0.0       0.06   13.8   0.0    1.5  1  2OG-FeII_Oxy_5  Putative 2OG-Fe(II) oxygenase


Domain annotation for each model (and alignments):
>> PhyH  Phytanoyl-CoA dioxygenase (PhyH)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  147.7   0.0   6.2e-47   5.6e-43       1     210 [.      19     291 ..      19     292 .. 0.92

  Alignments for each domain:
  == domain 1  score: 147.7 bits;  conditional E-value: 6.2e-47
                 HHHHSEEEETTSS-HHHHHHHHHHHHHH................................HHHCHTTCCSEEEEECEEESTTCCCEE...........C CS
        PhyH   1 feedGylviegflsaeevealraeieal................................ldralesgdkidfffeekaaadedgll...........e 56 
                 f+e+G+lvi++ ls ee+++l+ ++++l                                +d++l+sgdki+fffe +a+a  dg              
  EEA20859.1  19 FNENGFLVIPSYLSSEEIQSLLTTTNDLlenfdlanhpmtrfttgddgdaegdekakhvgDDYFLSSGDKIHFFFEPEAVAPPDGTTqdktprllkpkH 117
                 79***************************************************************************999998888888889999*999 PP

                 CCHHCHHHHTTH.......HHHHHHHHHHHTSCEEEE.EEEEEEEEEEEE-TTTCB-EEEEE-SGGGSTEESGCCEEEEEEESS-B-TTBT-EEEETTG CS
        PhyH  57 ksinkvghflhp.......rkvadlvrailgqdvyva.avlqsmyqdifkqpkiGgevqpwHqDstflptdpeesvvgvwialedateenGclrfiPGS 147
                  +ink+gh+lh         +++++  ai ++  ++  ++lqsm+  i+kqp+iGg+v p H+Ds+fl+t p +s+vg w+al dat+ n  l +  GS
  EEA20859.1 118 LAINKIGHALHSksppfekVTISKRNAAIAQSLGFKDpRCLQSMV--ICKQPSIGGPV-PAHRDSEFLYTSP-PSAVGYWVALQDATPGNASLGMWKGS 212
                 9***********99999998888888888888888779*******..***********.************9.************************** PP

                 GGS-CCGTCCHHCSGCCTTS.................CCCTTTGHGSCEEEE.BTTTEEEEEETTSEEEE-TB.SSSXEE CS
        PhyH 148 Hkweegplrrrlpeddteae.................ddeakkedeeeavpvevkaGdavlfhgrllHgsgaNrsdksRr 210
                 Hk ++g + rr+   ++  +                 ++ + +e++e +  ++vkaGd+vl+hg++lH+s+ N+sdksR 
  EEA20859.1 213 HKGRKGGHIRRRFVRAEG-GgttfiandgpslplgkdEEVSGQEEDEDFEILNVKAGDLVLIHGNVLHKSEKNTSDKSRY 291
                 ***999654333322222.24689***********9766777889999******************************95 PP

>> 2OG-FeII_Oxy_5  Putative 2OG-Fe(II) oxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   6.7e-06      0.06      38     100 ..     233     295 ..     224     296 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 6.7e-06
  2OG-FeII_Oxy_5  38 lkledprlavelgaparkeeakeenqslvdvkpkeGdlvlFPswlrHevlpnegeeeRisisf 100
                     + + +++++    +++++ + +ee++++  ++ k+Gdlvl    + H+  +n+++++R  + f
      EEA20859.1 233 TTFIANDGPSLPLGKDEEVSGQEEDEDFEILNVKAGDLVLIHGNVLHKSEKNTSDKSRYAYTF 295
                     556666666665666667777788999999****************************99888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (329 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       401  (0.022366); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2261.37
//
Query:       EEA20860.1  [L=163]
Description: hypothetical protein PMAA_046780 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (163 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       498  (0.0277762); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.25s 00:00:00.68 Elapsed: 00:00:00.40
# Mc/sec: 1207.85
//
Query:       EEA20861.1  [L=437]
Description: sulfate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.1e-63  210.1  35.1    4.8e-34  117.1  10.2    3.1  3  MFS_MOT1         Molybdate transporter of MFS superfamily
    3.4e-05   22.8  20.5    0.00068   18.5   2.1    2.8  2  Sulfate_transp   Sulfate permease family
    0.00068   18.4  33.0    0.00088   18.1  18.2    2.5  2  Xan_ur_permease  Permease family


Domain annotation for each model (and alignments):
>> MFS_MOT1  Molybdate transporter of MFS superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.1  11.8   3.6e-33   2.1e-29       1     111 []      24     138 ..      24     138 .. 0.98
   2 ?   -0.4   0.2      0.25   1.5e+03      75      93 ..     181     199 ..     161     213 .. 0.60
   3 !  117.1  10.2   8.1e-38   4.8e-34       2     111 .]     225     344 ..     224     344 .. 0.97

  Alignments for each domain:
  == domain 1  score: 102.1 bits;  conditional E-value: 3.6e-33
    MFS_MOT1   1 aelsgalgdlglTllnlvialaalaslsltalllsvGlmnlltglfggvPmc.....hgAgglaaqyrf.gartgaagillGlvllllgltgllerllr 93 
                 ae+sg+lgdlg T+l+l+ial++  ++sl+++l+++G++n+ltglf+g+P++     ++A++++a+  f + +++aagi+++++++++++tgll+++++
  EEA20861.1  24 AEISGSLGDLG-TFLPLAIALSINGTISLSSTLVFSGIANILTGLFFGIPLPvqpmkAIAAVAIANA-FtNGEIAAAGIFVAACIFVFSATGLLRWFAN 120
                 589********.******************************************************5.45***************************** PP

    MFS_MOT1  94 liPksvlgglllgaGleL 111
                 +iP +v++g+++gaGl+L
  EEA20861.1 121 VIPIPVVKGIQVGAGLSL 138
                 ****************98 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.25
    MFS_MOT1  75 lGlvllllgltgllerllr 93 
                 ++lv+l+ gl++++   ++
  EEA20861.1 181 YALVVLAAGLVFAIISATQ 199
                 3445555555554444444 PP

  == domain 3  score: 117.1 bits;  conditional E-value: 8.1e-38
    MFS_MOT1   2 elsgalgdlglTllnlvialaala........slsltalllsvGlmnlltglfggvPmchgAgglaaqyrfgartgaagillGlvllllgltg..ller 90 
                  +++ +g+l+lT+ln+via+++la        + s+t+++lsv++mnl++++fg++P+chg+gglaaqyrfgar+g+++++lG+++ll+g+++  +l+ 
  EEA20861.1 225 IVQAGIGQLPLTTLNSVIAVVHLAgdlfpevtTPSITSVGLSVSIMNLVSCWFGAMPVCHGSGGLAAQYRFGARSGSSVVFLGVLKLLFGFFFgnTLVG 323
                 57899**************************9667**************************************************************** PP

    MFS_MOT1  91 llrliPksvlgglllgaGleL 111
                 ll+ +P ++lg+++++aGleL
  EEA20861.1 324 LLKSFPYALLGIMVIAAGLEL 344
                 *******************98 PP

>> Sulfate_transp  Sulfate permease family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3  10.0   7.1e-05      0.42      57     193 ..      74     212 ..      34     216 .. 0.64
   2 !   18.5   2.1   1.1e-07   0.00068     283     365 ..     267     352 ..     264     360 .. 0.88

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 7.1e-05
  Sulfate_transp  57 pvavlslivgeiiakvaeeepekgieiattltllaGviqvllGllRLgflveflseavlsGfiaGaaivillsqikvllgle......rvskkes 145
                     pv  +  i++ +ia+     + ++ eia++ +++a  i+v+  +  L + +++++ +v+ G  +Ga++ +++++  +l +l         ++   
      EEA20861.1  74 PVQPMKAIAAVAIAN-----AFTNGEIAAAGIFVAACIFVFSATGLLRWFANVIPIPVVKGIQVGAGLSLIIAAGGSLSKLGwvtpswADNRIWA 163
                     455555555555554.....59999***************98888888*************************9999999985543222233333 PP

  Sulfate_transp 146 lvsvlsslftnlek.vnlakvvlgllllvvLlvtkellkklkkllvipa 193
                     +v++l+ l tn+ + +  a vvl++ l+++++ +++ ++ ++ +l+ip+
      EEA20861.1 164 IVAFLFLLATNYYRqIPYALVVLAAGLVFAIISATQAMDLPNFRLWIPV 212
                     4444444444443336667777777777777777776666666677776 PP

  == domain 2  score: 18.5 bits;  conditional E-value: 1.1e-07
  Sulfate_transp 283 lGfsNilsslfgglpatgafsrsavnikaGaktqlsglvsalvvllvllvlt....plleyiPkavLaaiiivagkglLvelkelkk 365
                     ++++N++s  fg++p+  +    a +++ Ga++  s ++++++ ll+  +++    +ll+ +P a L+ ++i ag++ L+++ e  +
      EEA20861.1 267 VSIMNLVSCWFGAMPVCHGSGGLAAQYRFGARSGSSVVFLGVLKLLFGFFFGntlvGLLKSFPYALLGIMVIAAGLE-LASVGESLN 352
                     689****************************************99999887722225899*****************.999888766 PP

>> Xan_ur_permease  Permease family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1  18.2   1.5e-07   0.00088      39     202 ..      51     196 ..      36     213 .. 0.69
   2 !    6.9   5.1   0.00036       2.2      58     140 ..     264     349 ..     255     363 .. 0.68

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 1.5e-07
                      .HHHHHHHHHHHHHHHHHTTT-----EEE-GGGHHHHHGGG-....HHHHHHHHHHHHHHHHHHHHHHHTT-SH.HHHHH--HHHHHHHHHHHH CS
  Xan_ur_permease  39 isatllasGiatllqllifgirlpillgssfafvtalmialGsaedieialagllgallvagvlfilisltglrgrlarlipPvvtgpvvlliG 132
                       s+tl++sGia +l  l+fgi+lp+    + a+v++   ++          ++++ a++  + + +++s+tgl  + a +ip  v+ ++ ++ G
       EEA20861.1  51 LSSTLVFSGIANILTGLFFGIPLPVQPMKAIAAVAIANAFTN---------GEIAAAGIFVAACIFVFSATGLLRWFANVIPIPVVKGIQVGAG 135
                      599************************999999994444443.........445555555556667788888888*******99999******* PP

                      HHHHHHHHHHTTSS-..BTT.B---HHHHHHHHHHHHHHHHHHHSSSTTTTTHHHHHHHHHHHHHHHHHH CS
  Xan_ur_permease 133 lslaqiavkkvgggwaavegltvvslkllllavvvllvilllsvflkglfsqlpiLigiiagwllalfmg 202
                      lsl+  a  + +++         + +   ++   + +++  l  ++ ++ +q+p+ + ++a+ l+++++ 
       EEA20861.1 136 LSLIIAAGGSLSKL---------GWVTPSWADNRIWAIVAFLFLLATNYYRQIPYALVVLAAGLVFAIIS 196
                      **997666666554.........23344444444444444444555566666777666666555555544 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.00036
                      TT-----EEE-GGGHHHHHGGG-.......HHHHHHHHHHHHHHHHHHHHHHHTT-SH...HHHHH--HHHHHHHHHHHHHHHHHHHH CS
  Xan_ur_permease  58 girlpillgssfafvtalmialGsa...edieialagllgallvagvlfilisltglrg..rlarlipPvvtgpvvlliGlslaqiav 140
                      g+ ++i+  +s  +++a+ +++Gs    +++  + ++ +  ++  gvl +l++++++     l + +p   +g++v+  Gl+la+++ 
       EEA20861.1 264 GLSVSIMNLVSC-WFGAMPVCHGSGglaAQYRFGARSGSS-VVFLGVLKLLFGFFFGNTlvGLLKSFPYALLGIMVIAAGLELASVGE 349
                      555555555554.444466666654543555555554443.344588899999888764114799*******************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (437 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       597  (0.033298); expected 358.6 (0.02)
Passed bias filter:                      253  (0.0141112); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.23s 00:00:00.74 Elapsed: 00:00:00.41
# Mc/sec: 3167.72
//
Query:       EEA20862.1  [L=356]
Description: YeeE/YedE family integral membrane protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.1e-05   23.3  15.0      0.006   16.2   3.9    3.2  3  Sulf_transp  Sulphur transport


Domain annotation for each model (and alignments):
>> Sulf_transp  Sulphur transport
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   3.9   3.4e-07     0.006     261     308 ..     105     152 ..      93     154 .. 0.85
   2 !    1.6   0.3     0.009   1.6e+02      24      72 ..     190     237 ..     186     247 .. 0.81
   3 !   12.3   0.2   5.1e-06     0.091      46      83 ..     300     336 ..     259     356 .] 0.78

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 3.4e-07
  Sulf_transp 261 llaallGGllMGfGarlAgGCniGaglsgiaslslsgwlalvflllGa 308
                  ++a l  G+l G+G+    GC++G++l g++ ls  + +a++ ++  a
   EEA20862.1 105 AAATLGLGVLTGWGTKNDQGCTSGHMLCGLSRLSARSLIATAIFFTTA 152
                  55556669********************************99988765 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.009
  Sulf_transp  24 alllaiavaavgfqllaaaglidlpksafpvvglivGGllFGvGMalaG 72 
                  a++++ +++a++++++ + ++++ + ++  v+++ + G+ FG+G+ ++G
   EEA20862.1 190 AVMTTSCISALFTTFVLGPKVLTRSYKSRRVFAY-LAGVQFGLGLLFSG 237
                  6788888999999999999999988888885555.56899*****9998 PP

  == domain 3  score: 12.3 bits;  conditional E-value: 5.1e-06
  Sulf_transp  46 dlpksafpvvglivGGllFGvGMalaGgCasgtlyrvG 83 
                  +l+ + ++ +  ivG+++FGv    +G+C++ ++ r++
   EEA20862.1 300 KLTVADIN-WRFIVGAVIFGVAWGSSGTCPGPAILRSV 336
                  45555666.899******************98888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (356 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       357  (0.0199119); expected 358.6 (0.02)
Passed bias filter:                      230  (0.0128284); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.23s 00:00:00.67 Elapsed: 00:00:00.39
# Mc/sec: 2719.79
//
Query:       EEA20863.1  [L=445]
Description: glutaminyl cyclase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.1e-30  105.4   0.0    5.4e-30  104.6   0.0    1.4  1  Peptidase_M28  Peptidase family M28


Domain annotation for each model (and alignments):
>> Peptidase_M28  Peptidase family M28
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.6   0.0     3e-34   5.4e-30      14     197 ..     168     414 ..     151     415 .. 0.85

  Alignments for each domain:
  == domain 1  score: 104.6 bits;  conditional E-value: 3e-34
                    EEEEEEE--B-TTTTCCT---TTTTHHHHHHHHHHHHHCHH.................GGCCSSEEEEEEEESSCSG........SSHHHHHHHHH CS
  Peptidase_M28  14 vlllgAHyDsvgvgrgpifvGAdDnAsgvaalLelarvlaa.................sgsrpkrgvrflffdaEEa........gllGSkafaka 84 
                    +l l AHyDs+++   ++f GA+D+A+++a+++  +r + a                  g +   g++++f+d+EEa        +l+GS+ +a+ 
     EEA20863.1 168 RLTLVAHYDSKYE--PKGFIGAIDSAAPCAMIMHAVRSIDAaltrkwkqmetegdameAGFDAYTGIQVIFLDGEEAfktwtnsdSLYGSRSLAE- 260
                    799*********7..4489***********************************9988666789******************************6. PP

                    HC.............CCTTEEEEEEECS-SSSS--EEE.........................HHHHHHCHHHHHHHHHHHHHTT-TTSCCEEEEE CS
  Peptidase_M28  85 kp.............elkkiaavlnlDmvgsggkellf.........................esgdkssselekelkalakpvgraaaedpfder 142
                    ++             +l+ i ++l+lD++gs+++ + +                         +s+++ +s+ e+++++  + ++ a++ + + ++
     EEA20863.1 261 TWgetayspmsifrtPLSSISLFLLLDLLGSKDPLIQSyfptthwayqsmadlerrlrslkqlKSSPNFDSKSEQTADEP-QWLADAEKGEHLLKA 355
                    4444456778899999******************999999*********9999999999555444444444444444422.224445555788888 PP

                    SSTT-STTHHHHTTT--EEEE....CTSSS-TTTTSTTSSGGGB-HHHHHHHHHHHHHH CS
  Peptidase_M28 143 sgrgrsDhspflkagvpvldl....aetgfpevyHtprDtldnidkdtlariaelvlel 197
                     +++++Dh+pfl++gv +l++     ++gfpev+Ht +D+ +++d +t+++++ lv ++
     EEA20863.1 356 WTTIQDDHLPFLRRGVEILHIidtpGRHGFPEVWHTINDDGEHLDLPTVEDWSMLVTAF 414
                    899******************777777889***********************999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (445 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       375  (0.0209158); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.26s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 2903.20
//
Query:       EEA20864.1  [L=276]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (276 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       356  (0.0198561); expected 358.6 (0.02)
Passed bias filter:                      258  (0.0143901); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 1850.51
//
Query:       EEA20865.1  [L=172]
Description: histone h1.3., putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (172 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       390  (0.0217525); expected 358.6 (0.02)
Passed bias filter:                      277  (0.0154498); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.25s 00:00:00.63 Elapsed: 00:00:00.40
# Mc/sec: 1295.42
//
Query:       EEA20866.1  [L=1197]
Description: DNA mismatch repair protein Msh6, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.6e-69  231.2   0.1    1.8e-68  230.3   0.1    1.5  1  MutS_V    MutS domain V
    1.2e-40  139.8   0.0    2.6e-40  138.7   0.0    1.6  1  MutS_III  MutS domain III
    1.4e-33  115.5   0.6    4.7e-33  113.8   0.1    2.2  3  MutS_I    MutS domain I
      7e-13   49.0   0.0      2e-12   47.6   0.0    1.8  1  MutS_II   MutS domain II
    1.1e-12   48.1   0.2    2.4e-12   47.0   0.2    1.6  1  MutS_IV   MutS family domain IV
  ------ inclusion threshold ------
      0.013   16.0   0.0      0.013   16.0   0.0    2.7  3  AAA_23    AAA domain
      0.038   13.7   0.0      0.078   12.7   0.0    1.4  1  AAA_29    P-loop containing region of AAA domain
      0.085   12.4   0.0       0.24   11.0   0.0    1.7  1  AAA_27    AAA domain
       0.21   11.3   3.4       0.11   12.3   0.2    2.1  2  AAA_21    AAA domain, putative AbiEii toxin, Type IV TA syste


Domain annotation for each model (and alignments):
>> MutS_V  MutS domain V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  230.3   0.1   8.9e-72   1.8e-68       2     186 ..     956    1142 ..     955    1144 .. 0.96

  Alignments for each domain:
  == domain 1  score: 230.3 bits;  conditional E-value: 8.9e-72
                  EEE-STTSSHHHHHHHHHHHHHHHHHT--BSSSEEEEE--SEEEEEE--------SS-HHHHHHHHHHHHHTT--TTSEEEEESTS-SS-HHHHHHH CS
      MutS_V    2 litGpnmaGkstylrqvalivllaqiGsfvpaekaeisivdkiftRvgasDdlakgkstFmvEmlEtasilknatekslvilDElGRGtstydGlai 98  
                  l+tG+n aGkst lr ++++v++aq+G+++p+++a++++vd+i++R+ga+D++  ++stF vE++Et++il++at kslvilDElGRGts+ydG+a+
  EEA20866.1  956 LLTGANAAGKSTILRMTCVAVIMAQVGCYIPCQSARLTPVDRIMSRLGANDNIFAAQSTFFVELSETKKILSEATPKSLVILDELGRGTSSYDGVAV 1052
                  79*********************************************************************************************** PP

                  HHHHHHHHHHTT--EEEEEES-GGGGGHHHHSTTEE..EEEEEEEEETTEEEEEEEEEES--SS--HHHHHHHTT--HHHHHHHHHHHHH CS
      MutS_V   99 alavaeyllekikaktlfatHyheltklaekleevk..nlhlavkeeeedivflykvkegaaeksyGikvaklaglPesvverArevlke 186 
                  a+av++++++++ +  +fatHyh+l++  e+++e++  +++++v++ee++++flyk+++g+ae s+G++ a++ g+P++v+e+A++++k+
  EEA20866.1 1053 AQAVLHHIATHVGSLGFFATHYHSLAAEFENHPEISpkRMRIHVDDEERRVTFLYKLEDGVAEGSFGMHCASMCGIPNKVIENAENAAKQ 1142
                  **********************************984466667778999************************************99887 PP

>> MutS_III  MutS domain III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.7   0.0   1.3e-43   2.6e-40       1     191 []     609     900 ..     609     900 .. 0.77

  Alignments for each domain:
  == domain 1  score: 138.7 bits;  conditional E-value: 1.3e-43
                 HHHHHTTSSS-.TTS.SSSS-HHHHH---SSHHHHHHHHHHHH--BS-HHHHHHHHHHHHH.T..TT.HHHHHHHHTT---HHHHHHHHHTT---HHHH CS
                 xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    MutS_III   1 aTlrnLeilen.lrggskegsLlgvldrTvTamGaRlLrewllqPltdleeInaRldaVee.leneelreelrellrrlpDleRllsrislgkakardl 97 
                 +Tl nLei+ n ++g ++eg+L+++l+r+ T++G+R++++w+++Pl+d+++InaR daV+    ++++r+++ ++l ++pDleRl+sri++g +k +d+
  EEA20866.1 609 QTLINLEIFANsFDG-GSEGTLFQLLNRCITPFGKRMFKQWVCHPLVDIDKINARFDAVDAlNADSTIRDQFSSQLTKMPDLERLISRIHAGACKGQDF 706
                 7*******9986776.67******************************************9666889999999*************************9 PP

                 HHHHHHHHHHHTTTTT---SSTHHHHH....................................HHHHHHHHHHB-SS--SSGGGS--B-T......... CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx....................................xxxxxxxxxxxxxxxxxxxxxxxxxxx......... RF
    MutS_III  98 kallealkaleelvallekeklaesee....................................eslaelleeaideeplalekegedlra......... 151
                 +++le ++++e ++ ll++  +    e                                    +       e                 +         
  EEA20866.1 707 LRVLEGFEQIEYTMGLLKDLGSG---EgligklvssmpdlvspleywktafdrlkakengilvP-------E-----------------Qgieedfdas 778
                 99999999988888888666543...23446666666665555555555554444433333331.......2.................0222222333 PP

                 ..................................................................................HHHHHHHHHHHHHHHHH CS
                 ..................................................................................xxxxxxxxxxxxxxxxx RF
    MutS_III 152 ..................................................................................iealeqelfqelleeve 168
                                                                                                     ++ +e+  ++ ++++
  EEA20866.1 779 qatieqihrdlenllkqarrdlgstaicyrdngkeiyqlevpikvknipktwdqmsatkqvkryyfpelralirklqeaqetHSQIVKEVAGRFYARFD 877
                 33333333555557788888888889999999999*************************************998866544433333666667777776 PP

                 HTHHHHHHHHHHHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxx RF
    MutS_III 169 ealerlrrlaealaeLDvllSlA 191
                 e  e++++ ++++a+LD+l+SlA
  EEA20866.1 878 EDYETWLKSIRIVAQLDCLISLA 900
                 668*******************9 PP

>> MutS_I  MutS domain I
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.8   0.1   2.4e-36   4.7e-33       2     111 ..     309     428 ..     308     430 .. 0.95
   2 ?   -2.8   0.0       3.7   7.4e+03      23      40 ..     869     886 ..     857     892 .. 0.76
   3 ?   -3.0   0.0       4.2   8.3e+03      55      67 ..    1121    1134 ..    1113    1137 .. 0.77

  Alignments for each domain:
  == domain 1  score: 113.8 bits;  conditional E-value: 2.4e-36
                 HHHHHHHCCCHH-TTCEEEEEETTEEEEECHHHHHHHHHCSSSSTT.ESSSSC.EEEEEEEHHHHHHHHHHHHHTT-EEEEEEE-S-HHHH........ CS
      MutS_I   2 plmkqylelkkkykdavlffrvGdfYelfgeDAviaareleitltkrkkssekeipmagvPehalekylrkLvekgykVavveqtetpaek........ 92 
                 p++kqy+e+k+k  d+++ff++G+fYel+++DA+i++++++++lt    ++ + ++m+gvPe++l+++++++v+kgyk+a+v+q+e++  k        
  EEA20866.1 309 PFEKQYWEIKQKFWDTIVFFKKGKFYELYENDATIGHQLFDLKLT----DRVN-MRMVGVPEMSLDHWANQFVAKGYKIARVDQSESALGKemrerddk 402
                 9********************************************....6677.*********************************999999****** PP

                 .......S.S--EEEEEEEBTTC-TT CS
      MutS_I  93 .......kgvvkrevvrviTpGtltd 111
                        ++++kre++ v+T Gtl++
  EEA20866.1 403 kakvgkeDKIIKRELACVLTAGTLVE 428
                 999998746**************987 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 3.7
                 ETTEEEEECHHHHHHHHH CS
      MutS_I  23 vGdfYelfgeDAviaare 40 
                  G+fY  f eD ++  + 
  EEA20866.1 869 AGRFYARFDEDYETWLKS 886
                 699*******97776665 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 4.2
                  ..EEEEEEEHHHHH CS
      MutS_I   55 e.ipmagvPehale 67  
                  +  +m+g+P++ +e
  EEA20866.1 1121 HcASMCGIPNKVIE 1134
                  4478*****98876 PP

>> MutS_II  MutS domain II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.6   0.0     1e-15     2e-12       2     131 ..     439     584 ..     438     589 .. 0.80

  Alignments for each domain:
  == domain 1  score: 47.6 bits;  conditional E-value: 1e-15
                 EEEEEEEE..TTTSEEEEEEEETTTTEEEEEEEEE...-HHHHHHHHHH-ESEEEEESS-SCCCH.....HHHHHCHCTTT-EEEEESC.CCCSHCCHH CS
     MutS_II   2 ylaAisek..regrrvGlafiDlstgefvvsefed...feeleaeLsrlsPkElllpedlsesta.....eeessklrelrsrvgvret.vefesekas 89 
                 y++Ai+e      +++G+af+D++tg+f++sef+d    +++e+ +++  P Elll++++ +++a     +       +l++ ++  ++ +e +++ ++
  EEA20866.1 439 YCVAIKEIilDGLPAFGIAFVDTATGQFYLSEFKDdadMTKFETFVAQTRPQELLLEKSAVSQKAmrilkN--NTGPTTLWNHLKPGKEfWEADIAVRE 535
                 666755555445566*********************************************99988755322..22233455566666554667777778 PP

                 HHCHHHB--STTTTTTT.......GGG-HHHHHHHHHHHHHCCCCCSCC CS
     MutS_II  90 erleedfsvedldgfgl.......ekekklalaAlgalisYleetqkek 131
                  +  ++f   d d+++          ek+ a++A+gal++Yl  +++++
  EEA20866.1 536 LDASDYFVSPDSDNINAwpqvlreAREKENAMSAFGALVQYLRVLKLDR 584
                 88888888999999999******9899***************9988875 PP

>> MutS_IV  MutS family domain IV
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.0   0.2   1.2e-15   2.4e-12       1      91 [.     770     859 ..     770     860 .. 0.97

  Alignments for each domain:
  == domain 1  score: 47.0 bits;  conditional E-value: 1.2e-15
                 TTSHHHHHHHHHHHHHHHHHHHHHCCCCCCCT-TTBEECCCSSSEEEEEE-TCCCTTT--SEEEEEECTCEEEEECCCHHHHHHHHHHHHH CS
     MutS_IV   1 gfdeeLdelrdrleelekeleeleekereklgikslkveynkvlGyylevtrseakkvpkefirlqtlknseryttaelkkleaelleaee 91 
                 g++e++d +++++e++ ++le+l+++ r++lg   + +++n++  y+lev+ +  k++pk + +++ +k+ +ry+ +el++l ++l+ea+e
  EEA20866.1 770 GIEEDFDASQATIEQIHRDLENLLKQARRDLGSTAICYRDNGKEIYQLEVPIKV-KNIPKTWDQMSATKQVKRYYFPELRALIRKLQEAQE 859
                 6899***********************************************887.**********************************98 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.4       4.7   9.4e+03     116     116 ..     138     138 ..      77     211 .. 0.48
   2 ?   -0.5   0.4      0.72   1.4e+03     118     172 ..     786     864 ..     749     888 .. 0.53
   3 ?   16.0   0.0   6.7e-06     0.013      17      41 ..     947     974 ..     933     977 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 4.7
      AAA_23 116 e 116
                 e
  EEA20866.1 138 E 138
                 1 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.72
      AAA_23 118 eqfisellgskkiil.nlilflgqerfeefelkdkke.......................rleelekeleeledekkll 172
                  + +++ll++  + l +  +++ +  +e  +l+ + +                       +l++l+++l+e++++ +++
  EEA20866.1 786 HRDLENLLKQARRDLgSTAICYRDNGKEIYQLEVPIKvknipktwdqmsatkqvkryyfpELRALIRKLQEAQETHSQI 864
                 2333333333333332222222222222333322222333333444444444466677777777777777777665554 PP

  == domain 3  score: 16.0 bits;  conditional E-value: 6.7e-06
      AAA_23  17 F...skgltlItGpNGaGKTTildAikl 41 
                 +   +  ++l+tG N aGK+Til+  + 
  EEA20866.1 947 LggdKASINLLTGANAAGKSTILRMTCV 974
                 45545579***************87665 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   3.9e-05     0.078      22      39 ..     952     969 ..     942     980 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 3.9e-05
      AAA_29  22 kgatlltGpsGsGKSTll 39 
                 +++ lltG++ +GKST+l
  EEA20866.1 952 ASINLLTGANAAGKSTIL 969
                 4478*************8 PP

>> AAA_27  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00012      0.24      16      44 ..     942     970 ..     933     974 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00012
      AAA_27  16 drsldfsaeeadlhliyGpNEAGKstalr 44 
                  + ++++ ++a++ l+ G+N AGKst+lr
  EEA20866.1 942 PNDVQLGGDKASINLLTGANAAGKSTILR 970
                 567899999******************97 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.3      0.89   1.8e+03     118     218 ..      71     175 ..      32     345 .. 0.72
   2 ?   12.3   0.2   5.3e-05      0.11       1      17 [.     954     970 ..     954     971 .. 0.95

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.89
      AAA_21 118 irggvsvfslkelsvsepndlqfgkaltditsrawsllllldglrke....rigllnifadyfgfakekrllqrlvrslklveielsdlgegeeliasv 212
                 +++ ++ + +++l++++++d + ++  ++ t   ++ ++++++l +     ++ ++  ++++   ++e  ++ + +r+++++ ie +d+   + + a  
  EEA20866.1  71 TKSSIKKKPAQNLTPAPSSDVIEPDEDDSATPKVSKNAQDDQSLTPSrrtkKKVNYMESDSEGVDDDEEIFRPQPSRKRRRPAIESEDEFQDDGKDAHM 169
                 555555555566666666666666666666666666666666666666655555555555555555555556666666555555555555444444444 PP

      AAA_21 213 derlre 218
                 +e++ +
  EEA20866.1 170 SEDEMD 175
                 443333 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 5.3e-05
      AAA_21   1 lnvliGpNgsGKSnLLd 17 
                 +n+l+G+N++GKS++L+
  EEA20866.1 954 INLLTGANAAGKSTILR 970
                 79*************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1197 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1053  (0.0587317); expected 358.6 (0.02)
Passed bias filter:                      560  (0.0312343); expected 358.6 (0.02)
Passed Vit filter:                        76  (0.00423894); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 1.02u 0.36s 00:00:01.38 Elapsed: 00:00:00.52
# Mc/sec: 6954.37
//
Query:       EEA20867.1  [L=636]
Description: tyrosyl-tRNA synthetase, mitochondrial precursor (tyrosine--tRNA ligase) (tyrrs) [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      2e-73  247.3   0.0    2.7e-73  246.9   0.0    1.1  1  tRNA-synt_1b  tRNA synthetases class I (W and Y)
      9e-43  144.9   0.0    1.6e-42  144.1   0.0    1.4  1  TyrRSs_C      Tyrosyl-tRNA synthetase C-terminal domain
  ------ inclusion threshold ------
      0.012   15.3   0.0      0.027   14.2   0.0    1.6  1  S4            S4 domain


Domain annotation for each model (and alignments):
>> tRNA-synt_1b  tRNA synthetases class I (W and Y)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  246.9   0.0   4.5e-77   2.7e-73       4     292 ..     115     434 ..     113     435 .. 0.97

  Alignments for each domain:
  == domain 1  score: 246.9 bits;  conditional E-value: 4.5e-77
                   S--EEEEEEETSSS.-BGGGHHHHHHHHHHHHTTSEEEEEEEHHHHHTTTTT.-SSHHHHHHHHHHHHHH..HHHHHHHTCHTTT............ CS
  tRNA-synt_1b   4 rplrvysGidPTgk.lHlGylvplkklvelqkaghevffliaDlhAiigdps.kaeerklrkreevlena..ikaqlakgldpek............ 84 
                   +++ +y+G+dPT++ lH+G+++p+++l++  + g+ v f++++++A  gdp+ +  +r  ++r+ +++n+  ++ ql+++    +            
    EEA20867.1 115 KRTGLYTGVDPTAPsLHVGHMLPIMVLAWAFNWGYPVHFILGGATARFGDPTgRLGPRATEHRSVRVANMaaMHMQLKRISASIEdygrrygyvkew 211
                   57789****************************************************************99*******99666556*********** PP

                   ...EEEEETHHHHTTHHHHHHHHHHHTTCBHHHHHHHHHCCHHCSSSC--BHHHHHHHHHHHHHHHHTCHS...EEEEEGGGHHHHHHHHHHHHHHH CS
  tRNA-synt_1b  85 ...aevvlqsewlehlelaellrdlgklgslnrmlqfksvkkrleegegislgeftYplLqaaDilllkad...lvpgGsDQkqnielgrdlarrfn 175
                      + + +++ w++++   e+lrdlg +++l  ml +++vk+rle  +g+s++ef+Ypl+qa+D++ l ++   +++gG DQ +ni +g d ++++ 
    EEA20867.1 212 awkRALTNNNVWWNKTPFVEVLRDLGMHMRLGPMLGRDTVKTRLEG-SGMSFAEFSYPLMQAWDWWELFKKgvqVQVGGADQFGNILFGMDAVKHVA 307
                   *9999*****************************************.69*********************9999*********************** PP

                   HH...........STTSS-EEEEET-BBSTTSSSBTTCETTCGC-BTTCCHHHHHHHHHHCHCSTTCSHHHHHHHHHTHHHCHHHHHHHHCCSEE.E CS
  tRNA-synt_1b 176 kk...........evfkkpegltvplltgldGekKmSKSagnsaIfLddekesvkkkiqkavtdsdeevekllklktelsnelierleavsgkkp.k 260
                   k+           +  +kp+glt+pllt ++Ge K++KSagn a++Ld++ +s  +++q++v+++d+ vek+lk++t+l+ e i +++a+s+++p k
    EEA20867.1 308 KNtaieidrrpveDDVDKPVGLTTPLLTTSSGE-KIGKSAGN-AVWLDKDMTSTFELYQYFVRTPDDVVEKYLKMFTFLPLEKIAEIMAESTQDPsK 402
                   *************999*****************.********.****************************************************** PP

                   SSHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH CS
  tRNA-synt_1b 261 reaeellaeevtklvhggdlkkalaealnell 292
                   r a++ la+e ++ vhg   ++a+a ++++l+
    EEA20867.1 403 RIAQHALAKEFVDIVHGPIEAEAAATQHRQLF 434
                   *****************************998 PP

>> TyrRSs_C  Tyrosyl-tRNA synthetase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  144.1   0.0   2.6e-46   1.6e-42       2     119 ..     479     595 ..     478     596 .. 0.98

  Alignments for each domain:
  == domain 1  score: 144.1 bits;  conditional E-value: 2.6e-46
                 TTTSTT-EEEE--GGGGGS-SHHHHHHHTTS-STHHHHHHHHHHT-EEEEE--S---SSS-SSS--------SHHHHHHHTT-SS-EEEEESSS-EEEE CS
    TyrRSs_C   2 tlanapkvdvkLPksLvlnksiariLyaaGLasskseghrliakkgayvgsrpgkkkgekedelsftpiktwkpeetkkflidgklLiLrkGkwkvrii 100
                 +++n+++ +v LP+sL l++++a++Ly+aGL+ss+seghrli+ kg+ +gsrpg ++ge++d+lsftpiktw p + ++flid++lLi+++Gkwk+++i
  EEA20867.1 479 NYKNMESNRVLLPRSLALEQPLAKVLYNAGLVSSNSEGHRLIVGKGVSIGSRPG-DSGEMSDALSFTPIKTWVPGKNSDFLIDNNLLIVKIGKWKLKLI 576
                 67899*************************************************.******************************************** PP

                 E---HHHHHHHTTTSHHHH CS
    TyrRSs_C 101 eivsDeefeasgltapgee 119
                 e+++Deefe++gl++pg+ 
  EEA20867.1 577 ELIDDEEFEKRGLDVPGWA 595
                 ******************7 PP

>> S4  S4 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   4.5e-06     0.027       1      31 [.     498     528 ..     498     531 .. 0.93

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 4.5e-06
                 EEHHHHHHHTTSSSSHHHHHHHHHTTTEEET CS
          S4   1 rRLdkvlarlglassrreArqlIehGrVlVN 31 
                 ++L kvl+++gl+ss +e  +lI +++V + 
  EEA20867.1 498 QPLAKVLYNAGLVSSNSEGHRLIVGKGVSIG 528
                 589*************************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (636 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       558  (0.0311228); expected 358.6 (0.02)
Passed bias filter:                      480  (0.0267723); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 4240.95
//
Query:       EEA20868.1  [L=688]
Description: aspartyl-tRNA synthetase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.4e-90  303.6   0.0    3.7e-90  302.2   0.0    1.6  2  tRNA-synt_2      tRNA synthetases class II (D, K and N)
     0.0003   20.7   0.0     0.0014   18.5   0.0    2.0  2  tRNA_anti-codon  OB-fold nucleic acid binding domain
  ------ inclusion threshold ------
      0.011   15.8   0.0      0.019   14.9   0.0    1.5  1  tRNA-synt_2b     tRNA synthetase class II core domain (G, H, 


Domain annotation for each model (and alignments):
>> tRNA-synt_2  tRNA synthetases class II (D, K and N)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.1      0.27   1.6e+03       7      37 ..     113     143 ..     108     145 .. 0.85
   2 !  302.2   0.0   6.2e-94   3.7e-90       6     313 ..     206     660 ..     202     661 .. 0.97

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.27
                  HTHHHHCCSHHHHHHHHHHHHHHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2   7 knryldlrtekvskvlrlrstvtkavrkyle 37 
                  k  +++l  + +++++++ s++ + v++ l+
   EEA20868.1 113 KLSFVRLTDPTMRQNIQIISSAKNEVHQQLK 143
                  6678999999***********9999999887 PP

  == domain 2  score: 302.2 bits;  conditional E-value: 6.2e-94
                  HHTHHHHC.CSHHHHHHHHHHHHHHHHHHHHHHHT..T-EE----SEESS--SSSS--EEEEETTT.TEEE-E-S-SHHHHHHHHHCTHSEEEEEEEE CS
                  xxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2   6 lknryldl.rtekvskvlrlrstvtkavrkyleen..gfieietPiLsksdteegarlFkvksrekekeffaLtqspqlylellivagidrvfqiara 100
                   ++r+l+l   + +++ lr+rs++ k  r+ le+    fieietP+L+ks t+egar+F v++r k +  +aL+qspq+y+++l+++gi r++q+ar+
   EEA20868.1 206 AEQRHLQLrSDRGLREALRFRSEARKVCREELENMspPFIEIETPLLFKS-TPEGAREFIVPTRRK-GLAYALPQSPQQYKQILMASGIPRYYQFARC 301
                  579*****555679******************998668************.**************9.77788************************** PP

                  E--S--BTTB-S-CEEEEEEEEET-SCHHHHHHHHHHHHHHHHHHHHCSCCCCCHTTTTTSEE-SSS-EEEEHHHHHHHHHTS-SS--HHHHHHHHH. CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx. RF
  tRNA-synt_2 101 FRaEdsrtdrhlaEFtqieaemsfieeedimqvleelikslvkevlessakdiefvirrnskdlkkpfkrltykeaieklneigkdldkaderalvk. 197
                  FR+Ed+r+dr++ EFtq+++emsf++ ed+m+ +e+++++l++ +  ++            +  ++pf r++y+ea+ +      ++dk+d+r+ ++ 
   EEA20868.1 302 FRDEDLRADRQP-EFTQLDLEMSFATGEDVMKSIEKVVRKLWSSL-LNI------------DLGTQPFTRMPYQEAMGR-----FGSDKPDTRLGMEi 380
                  ************.********************************.555............234556************.....9************* PP

                  .................................................................................................. CS
                  .................................................................................................. RF
  tRNA-synt_2 198 .................................................................................................. 197
                                                                                                                    
   EEA20868.1 381 vrldymlpvdlvqkitpltdpivegfklesedndpsktlelvtrfldspagvefnknpdggpgifvydakkplrglmpfgfeaaerveellepdhgdl 478
                  ************************************************************************************************** PP

                  .....................................HS--SEEEEEEEB...................GGGSTTCBBBSTTS.........TTBBSE CS
                  .....................................xxxxxxxxxxxxx...................xxxxxxxxxxxxxx.........xxxxxx RF
  tRNA-synt_2 198 .....................................keknepvfvtdfP...................aelkpFyarkeedd.........kkltes 230
                                                        +++++++v+dfP                   ++++pF+a+k+  d           ++++
   EEA20868.1 479 ivlqarknapfsggstplgdlrkalhseavkagvkeaPKGFNFLWVVDFPlfspidenepgqggtaglaSTHHPFTAPKSAADvdlmvadpaAVVADH 576
                  *************************************9*******************************************99********999**** PP

                  EEEEETTEEEEEEEEB--SHHHHHHHHHHCCHH.SSSGGGGHHHHHHHHCT--SEEEEEEEHHHHHHHHCT-SSGGGCSSS-XX CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2 231 yDllingvElvgGslRiedpeeleeklkskgld.eeaeekfswylealeyGapphgGlglGldRlvmlllgsesIrdviaFPkl 313
                  yDl++ngvEl+gGs Ri+d +++e ++++  +   +  ++fs++leal+ G+pph+G++lG+dRl++++lg+es+rdviaFPk 
   EEA20868.1 577 YDLIVNGVELGGGSRRIHDARVQEIVFRDILKMpASRLTEFSHLLEALKAGCPPHAGIALGFDRLIAIMLGKESVRDVIAFPKS 660
                  *****************************998889999********************************************95 PP

>> tRNA_anti-codon  OB-fold nucleic acid binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0      0.13   7.7e+02      39      61 ..      85     107 ..      78     109 .. 0.84
   2 !   18.5   0.0   2.4e-07    0.0014      13      72 ..     109     185 ..      98     189 .. 0.80

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.13
                      HHHHHTTS-TTSEEEEEEEEEEC CS
  tRNA_anti-codon  39 atklaenlkeGdvvrvtGrvkrr 61 
                      + +l++n  +Gd v   G+++ r
       EEA20868.1  85 FPSLLKNASPGDTVVLHGYLGNR 107
                      557889999**********9876 PP

  == domain 2  score: 18.5 bits;  conditional E-value: 2.4e-07
                      EEETTEEEEEEEETT..EEEEEEEET.HHHHHHHTTS-TTSEEEEEEEEEECTTS..............SEEEEEEE CS
  tRNA_anti-codon  13 rsggkvifidlrDgt..griqvvlfr.eeatklaenlkeGdvvrvtGrvkrrpgg..............elelkvee 72 
                        ++k++f+ l+D t   +iq++    +e+ +++++l+ ++ v + G+v++ +g                le++ ++
       EEA20868.1 109 DISKKLSFVRLTDPTmrQNIQIISSAkNEVHQQLKSLPSNSPVAIQGTVQAKKGSgegereapdvekidSLEISLTN 185
                      6679***********999******9999************************7776666666666666666666555 PP

>> tRNA-synt_2b  tRNA synthetase class II core domain (G, H, P, S and T)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   0.0   3.2e-06     0.019      38      95 ..     294     346 ..     286     510 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 3.2e-06
                   EEEEEEEEEBTTTSTBCTTTB-SEEEEEEEEEEESGGGHHHHHHHHHHHHHHHHHHTT CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2b  38 klyqiqtkyRdEksdsrGLlRvreFhqkdgyvfhaeaslddslrdlikaisriferlg 95 
                   ++yq+ +++RdE        R+ eF+q d ++  a +  +d+++ ++k++ +++++l+
    EEA20868.1 294 RYYQFARCFRDEDL-RAD--RQPEFTQLDLEMSFATG--EDVMKSIEKVVRKLWSSLL 346
                   79**********97.335..999*******9888866..6788888888888888774 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (688 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       281  (0.0156729); expected 358.6 (0.02)
Passed bias filter:                      274  (0.0152825); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.28s 00:00:00.90 Elapsed: 00:00:00.46
# Mc/sec: 4447.28
//
Query:       EEA20869.1  [L=599]
Description: alpha-1,3-glucanase/mutanase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   3.5e-131  437.5   5.1   4.2e-131  437.2   5.1    1.1  1  Glyco_hydro_71  Glycosyl hydrolase family 71
  ------ inclusion threshold ------
       0.13   12.4   0.0       0.35   11.1   0.0    1.6  1  NPCBM           NPCBM/NEW2 domain


Domain annotation for each model (and alignments):
>> Glyco_hydro_71  Glycosyl hydrolase family 71
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  437.2   5.1  4.7e-135  4.2e-131       1     374 [.      38     427 ..      38     428 .. 0.95

  Alignments for each domain:
  == domain 1  score: 437.2 bits;  conditional E-value: 4.7e-135
  Glyco_hydro_71   1 VfaHfmvgnt.enytasdwekDiklAkaagiDgFaLNigskdswtaeqladayeaAeavgfkLflSfDmavagawpk...sevislikkyashpa 91 
                     VfaHfm+g+t ++ +++d+++D+++Ak++giD+FaLNig  d++t++ql  ay++A+++g+k+f+SfD+++   w++   +++ + i++ya+ p 
      EEA20869.1  38 VFAHFMIGITsDRSSSADYDADMQRAKSYGIDAFALNIGV-DPYTDQQLGFAYDSAARNGMKVFISFDFNW---WNTgqaTAIGQKIAQYAGLPG 128
                     9*********9999*************************8.*****************************9...7777779************** PP

  Glyco_hydro_71  92 qlkvngkplvSTFeGeknaedwasiksalteeiffvPdfsslgaaaaaekaldvvDGlfsWeaWpkgatn.........mstetDeaylsalkgk 177
                     qlkv+gk++vS+F+G+++  ++ +++sa+++e+ff+P+f+ +       ++++ vDGl++W+ Wp++++n            + D+ y+sal+gk
      EEA20869.1 129 QLKVDGKVFVSSFAGDGV--NIGAMRSAAGVELFFAPNFHPSY-----GTDMSNVDGLLNWMGWPSNGNNkaptsgatvSVEQGDNDYISALAGK 216
                     ******************..88899999889*********444.....335788**************888******9888899*********** PP

  Glyco_hydro_71 178 pYmmpvSpwffthlgkesyn.knwvwrgddlwakRweqvlelqpdfveiitWNDygEShYigplkekkaqdgsskyvegmpHdgwrdllkyyiaa 271
                     +Y++p Spwf th+g+e  + knwv+ +d lw++Rw+++l+l p+f+ei+tWNDygEShYigpl++ +++dg+sk+v++mpHdgw+d++k++iaa
      EEA20869.1 217 AYIAPASPWFSTHFGPEVSYsKNWVFPSDLLWYNRWQELLKLGPRFIEIVTWNDYGESHYIGPLSSPHTDDGASKWVNDMPHDGWLDMAKPFIAA 311
                     **************9987545************************************************************************** PP

  Glyco_hydro_71 272 yKtgsk..kpaitedklvlwyRphpkkakcssgdtt..............gnpanaelleDkvfvvallkspatvtvsvggkesetfsvkaGvnk 350
                     +K+g++  +++it+d+lv+wyRp+ k+++c+++dt+              g+p+++e+++D+vfvv ll++pa+vtv++gg+++ tf+++aG+n+
      EEA20869.1 312 FKAGATtvDNYITNDELVYWYRPTLKNVNCDATDTCmnpsasnssgnyflGRPNGYETMQDSVFVVSLLTAPAQVTVTSGGNSQ-TFQASAGANA 405
                     ****99999***************************88888888888888888888*************************999.99******** PP

  Glyco_hydro_71 351 lsvpfngetGkvkvsvvrngktva 374
                     ++vp+   +G++++sv+rng+tv 
      EEA20869.1 406 FQVPM--GVGSQTFSVTRNGATVF 427
                     *****..9*************996 PP

>> NPCBM  NPCBM/NEW2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   3.9e-05      0.35      45      95 ..     381     433 ..     379     435 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 3.9e-05
                 E-BSSEEEE-TTSEEEEEEEEEE-TTS..TTSSE-EEEEEETTEEEEETT-EE CS
       NPCBM  45 hanseitydlegkytrftaavGvddev..gqkgsvkFevlaDgkelyesgvlk 95 
                  a++++t+  +g+ ++f+a +G + ++   + gs +F+v   g ++++ + lk
  EEA20869.1 381 TAPAQVTVTSGGNSQTFQASAGANAFQvpMGVGSQTFSVTRNGATVFQGTSLK 433
                 699************************9988*************999987765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (599 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       521  (0.0290591); expected 358.6 (0.02)
Passed bias filter:                      266  (0.0148363); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.46
# Mc/sec: 3930.91
//
Query:       EEA20870.1  [L=198]
Description: nuclear movement protein NudC [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      3e-16   60.2   0.0    5.9e-16   59.2   0.0    1.5  1  CS        CS domain


Domain annotation for each model (and alignments):
>> CS  CS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.2   0.0   3.3e-20   5.9e-16       2      76 .]      37     114 ..      36     114 .. 0.94

  Alignments for each domain:
  == domain 1  score: 59.2 bits;  conditional E-value: 3.3e-20
                 SCEEEEETTEEEEEEE-TTCTTTTTCEEEEEETTEEEEEE.TSCEEEEECEBSS-BETTTEEEEEET....TEEEEEEEB CS
          CS   2 kydWyQtldeVvvtiyvkkvnikkkdvkvefkerslkvki.gkeklliegeLfgpIdpeesswties....kkveitLkK 76 
                  y+W+Qt+ e +v+i+v++ +ik++d++v ++++++kv + g + ++ieg++ +pI+ ++s+w +e+    k v i+L+K
  EEA20870.1  37 PYKWTQTIGEAEVSIPVPG-TIKGRDLDVVLTKTKIKVALkG-QAPIIEGDFPHPIQADDSTWMLETtptgKQVTIHLDK 114
                 69*****************.8*******************55.58899******************76999*******99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (198 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1212  (0.0676); expected 358.6 (0.02)
Passed bias filter:                      569  (0.0317363); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.23s 00:00:00.65 Elapsed: 00:00:00.38
# Mc/sec: 1556.97
//
Query:       EEA20871.1  [L=139]
Description: alkaline serine protease [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.2e-34  118.2   0.0    2.6e-34  117.9   0.0    1.0  1  Ribosomal_L14   Ribosomal protein L14p/L23e
  ------ inclusion threshold ------
      0.077   12.3   0.0       0.11   11.8   0.0    1.2  1  Endonuc-FokI_C  Restriction endonuclease FokI, C terminal


Domain annotation for each model (and alignments):
>> Ribosomal_L14  Ribosomal protein L14p/L23e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.9   0.0   2.9e-38   2.6e-34       4     119 ..      21     136 ..      19     139 .] 0.93

  Alignments for each domain:
  == domain 1  score: 117.9 bits;  conditional E-value: 2.9e-38
                    SS-EEE--SSSSBSEEEEEEETT-.....---EE-SSSEEEEEESSS-T...TTSSCEEEEEEEE-SS-EE-TTS-EEEESS-EEEEB-TTS-BSS CS
  Ribosomal_L14   4 lktrlkvaDNsgakevecikvlggk....krkaasvGdiivvsvkkakpkgkvkkgdvvkavvvrtkkevrrkdGsvirfddnaaVllnkkgeplG 95 
                    ++++++++DNsga+++++i+v g++    + +aa vGd+++++vkk+kp   + +++v+ avvvr++k++rr+dG ++ f+dna V++n+kge++G
     EEA20871.1  21 VGAVMNCCDNSGARNLYIISVAGAGarlnRLPAAGVGDMVMATVKKGKP---ELRKKVMPAVVVRQSKPWRRPDGIFLYFEDNAGVIVNAKGEMKG 113
                    6789******************999555344******************...899***************************************** PP

                    -.B-SBEEHHHHHH.-HHHHHTBS CS
  Ribosomal_L14  96 trifgpvarelrekkflkivslAp 119
                    + i+gpv +e++e  +++i+s + 
     EEA20871.1 114 SAITGPVGKEAAEL-WPRIASNSG 136
                    *************9.****99876 PP

>> Endonuc-FokI_C  Restriction endonuclease FokI, C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   1.2e-05      0.11      61      88 ..      88     117 ..      83     128 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 1.2e-05
  Endonuc-FokI_C  61 rkPdgivy..edndGiildtkayskGyslp 88 
                     r+Pdgi+   edn G+i+++k   kG +++
      EEA20871.1  88 RRPDGIFLyfEDNAGVIVNAKGEMKGSAIT 117
                     89***974469**********999998775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (139 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       225  (0.0125495); expected 358.6 (0.02)
Passed bias filter:                      198  (0.0110436); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.37u 0.25s 00:00:00.62 Elapsed: 00:00:00.39
# Mc/sec: 1057.94
//
Query:       EEA20872.1  [L=115]
Description: alkaline serine protease [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.4e-33  115.5   0.0    1.5e-33  115.4   0.0    1.0  1  Ribosomal_L14   Ribosomal protein L14p/L23e
  ------ inclusion threshold ------
      0.056   12.7   0.0      0.074   12.3   0.0    1.1  1  Endonuc-FokI_C  Restriction endonuclease FokI, C terminal


Domain annotation for each model (and alignments):
>> Ribosomal_L14  Ribosomal protein L14p/L23e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.4   0.0   1.7e-37   1.5e-33       8     119 ..       1     112 [.       1     115 [] 0.94

  Alignments for each domain:
  == domain 1  score: 115.4 bits;  conditional E-value: 1.7e-37
                    EE--SSSSBSEEEEEEETT-.....---EE-SSSEEEEEESSS-T...TTSSCEEEEEEEE-SS-EE-TTS-EEEESS-EEEEB-TTS-BSS-.B- CS
  Ribosomal_L14   8 lkvaDNsgakevecikvlggk....krkaasvGdiivvsvkkakpkgkvkkgdvvkavvvrtkkevrrkdGsvirfddnaaVllnkkgeplGtrif 99 
                    ++++DNsga+++++i+v g++    + +aa vGd+++++vkk+kp   + +++v+ avvvr++k++rr+dG ++ f+dna V++n+kge++G+ i+
     EEA20872.1   1 MNCCDNSGARNLYIISVAGAGarlnRLPAAGVGDMVMATVKKGKP---ELRKKVMPAVVVRQSKPWRRPDGIFLYFEDNAGVIVNAKGEMKGSAIT 93 
                    69****************999555344******************...899********************************************* PP

                    SBEEHHHHHH.-HHHHHTBS CS
  Ribosomal_L14 100 gpvarelrekkflkivslAp 119
                    gpv +e++e  +++i+s + 
     EEA20872.1  94 GPVGKEAAEL-WPRIASNSG 112
                    *********9.****99876 PP

>> Endonuc-FokI_C  Restriction endonuclease FokI, C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   8.2e-06     0.074      61      88 ..      64      93 ..      59     106 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 8.2e-06
  Endonuc-FokI_C 61 rkPdgivy..edndGiildtkayskGyslp 88
                    r+Pdgi+   edn G+i+++k   kG +++
      EEA20872.1 64 RRPDGIFLyfEDNAGVIVNAKGEMKGSAIT 93
                    89***974469***********99998775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (115 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       256  (0.0142785); expected 358.6 (0.02)
Passed bias filter:                      230  (0.0128284); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.35u 0.25s 00:00:00.60 Elapsed: 00:00:00.39
# Mc/sec: 887.55
//
Query:       EEA20873.1  [L=668]
Description: histone deacetylase RpdA/Rpd3 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.5e-81  274.3   0.0    2.9e-81  273.3   0.0    1.5  1  Hist_deacetyl  Histone deacetylase domain


Domain annotation for each model (and alignments):
>> Hist_deacetyl  Histone deacetylase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  273.3   0.0   1.6e-85   2.9e-81       1     305 [.      39     328 ..      39     330 .. 0.94

  Alignments for each domain:
  == domain 1  score: 273.3 bits;  conditional E-value: 1.6e-85
                    SCCGTHHHHHHHHHHHHT.THHHHCCE.EE-----HHHHTTTS-HHHHHHHHCHHHHCHHT.TTHCCHHHCCTSTSSSSSTHCTTTCCHHHHHHHH CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Hist_deacetyl   1 hpenpkRlsaileslaesvglldelelliqpseatkeellkvHskeYlelleslsnelkkkeeakekeleeiasklldddtpvspktlkaallavg 96 
                    hp++p+R++ + +sl  ++gl +++e + ++++a+k e++++H++eY+++l++++ +  ++    +ke ++++   + dd+pv++++++ + +++g
     EEA20873.1  39 HPMKPHRIR-MAHSLVMNYGLYKKME-IYRAKPASKYEMTQFHTDEYIDFLSKVTPDNMEQY---AKEQSKYN---VGDDCPVFDGLFEFCGISAG 126
                    89*******.***********99888.5*************************998877776...34444444...5799**************** PP

                    HHHHHHHHHHTTSSSEEEETT.SS--TT-BTTB-BTTBSS-HHHHHHHHHHHCC-SS-EEEEE-SSS--HHHHHHCTT-TTEEEEEEEE-CCTSTT CS
                    xxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Hist_deacetyl  97 avleavdavlsgsvkaafvlv.rPpgHHakaseasGFClvNnvaiaikylqakhelkrvailDvDvHhGnGteeafysdpdvltlSiHryegifyP 191
                    +++e++ ++ ++  k++++++  ++ HHak+seasGFC+vN+++++i +l + +  +rv+++D+DvHhG+G+eeafy +++v+t+S+H+y++ ++P
     EEA20873.1 127 GSMEGAARLNRN--KCDIAVNwAGGLHHAKKSEASGFCYVNDIVLGILELLR-F-KQRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKYGE-YFP 217
                    **********99..9***********************************99.3.36********************************966.9** PP

                    SS--TT---SGGGTTSEEEEEE-TT-BHHHHHHHHHHCHHHHHCCH--SEEEEEE-STTBTTSTT-S-BB-HHHHHHHHHHHCCCHGS-G.EEEEE CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Hist_deacetyl 192 gtgaledlgegkgkgfnlnvpleegtgdeeylkvfeeilrpvleefkPdlilvsaGfDalkgdplgelnlsvegykeltkklaeladkvkkvvlll 287
                    gtg+l d+g g+gk +++n+pl++g++d +y ++fe ++ +v+e ++P+++++++G D+l+gd+lg +nls++g++++++ ++++     ++++l+
     EEA20873.1 218 GTGELRDIGVGSGKYYAVNFPLRDGIDDVSYKSIFEPVISNVMEWYRPEAVVLQCGGDSLSGDRLGCFNLSMRGHANCVNFVKSFNL---PTLVLG 310
                    **************************************************************************************9...89**** PP

                    -S---HHHHHHHHHHHHH CS
                    xxxxxxxxxxxxxxxxxx RF
  Hist_deacetyl 288 eGGYnlealaravtavls 305
                    +GGY+++++ar ++  + 
     EEA20873.1 311 GGGYTMRNVARTWAFETG 328
                    ************987665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (668 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1497  (0.083496); expected 358.6 (0.02)
Passed bias filter:                      642  (0.0358079); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.79u 0.33s 00:00:01.12 Elapsed: 00:00:00.45
# Mc/sec: 4447.40
//
Query:       EEA20874.1  [L=336]
Description: proteasome regulatory particle subunit (RpnK), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    9.4e-33  112.7   0.0    1.8e-32  111.8   0.0    1.5  1  JAB         JAB1/Mov34/MPN/PAD-1 ubiquitin protease
    3.3e-12   46.8   0.7    5.2e-12   46.2   0.7    1.4  1  MitMem_reg  Maintenance of mitochondrial structure and functi
    4.9e-07   29.5   0.0    9.5e-07   28.6   0.0    1.5  1  Prok-JAB    Prokaryotic homologs of the JAB domain


Domain annotation for each model (and alignments):
>> JAB  JAB1/Mov34/MPN/PAD-1 ubiquitin protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.8   0.0   3.1e-36   1.8e-32       3     117 ..      32     142 ..      30     143 .. 0.97

  Alignments for each domain:
  == domain 1  score: 111.8 bits;  conditional E-value: 3.1e-36
                 SCEEEEEHHHHHHHHHHHHHHHHHTS--EEEEEEEESSSEEEEEEEEEEESEEEESSECEEEEEHHHHHHHHHHHHHHHCTT.SEEEEEEEESSSS-SS CS
         JAB   3 vqavhleslvllkildhalrtekeeeevmGlliGelnddttveitnvfalpfeetekdvdavsldqeylekksellkklrgr.ervvGWYhshpditvw 100
                  ++vh++sl+llk+l+h + +     evmGl++G + d++tv++++vfa+p+++t  +v+av+++ +  +k+++ lk++ gr e vvGWYhshp++++w
  EEA20874.1  32 SETVHISSLALLKMLRHGRAGVPM--EVMGLMLGDFVDEYTVRVVDVFAMPQSGTGVSVEAVDPVFQ--TKMMDFLKQT-GRpESVVGWYHSHPGFGCW 125
                 689*********************..**************************************999..*********9.999**************** PP

                 --HHHHHHHHHHHHHST CS
         JAB 101 lsevdvrtqalyqrmde 117
                 ls+vd++tq++++++++
  EEA20874.1 126 LSSVDINTQQSFEQLTP 142
                 ************99876 PP

>> MitMem_reg  Maintenance of mitochondrial structure and function
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.2   0.7   8.7e-16   5.2e-12       1      77 [.     177     290 ..     177     327 .. 0.91

  Alignments for each domain:
  == domain 1  score: 46.2 bits;  conditional E-value: 8.7e-16
  MitMem_reg   1 Eaeei..gvehllkpsiqdasstlstglnrqyyslki.......................................lqerldlikdYlkkveegelpvn 58 
                 E++++  +++hl+kpsiq    +l++glnr+yysl+i                                       +q  ++l++ Y k+v+e+ +  +
  EEA20874.1 177 EPRQTtsNLGHLNKPSIQ----ALIHGLNRHYYSLAInyrktgleenmlmnlhkhvwtealqmndfhedgkrnvesMQRLVELAEGYEKRVKEESTLTK 271
                 9*****************....**********************************************************************9998888 PP

  MitMem_reg  59 he.ilrnlqkllnllP..hlet 77 
                 ++  +r+++k++   P  h+e+
  EEA20874.1 272 EQlKTRYVGKVD---PkkHIED 290
                 889*********...9655554 PP

>> Prok-JAB  Prokaryotic homologs of the JAB domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.6   0.0   1.6e-10   9.5e-07       4      93 ..      41     135 ..      38     158 .. 0.74

  Alignments for each domain:
  == domain 1  score: 28.6 bits;  conditional E-value: 1.6e-10
    Prok-JAB   4 vlsalvaharrahpeEtcGlllgkeseseevivvplvnewsn....rfeipdpedslarlkf...earerglevvgiwHSHpggsarPSetDrrdaa 93 
                 +l ++++h r+  p E  Gl+lg+  ++  v+vv++  ++++    ++e  dp  + ++  +   + + r ++vvg +HSHpg +   S+ D+++ +
  EEA20874.1  41 ALLKMLRHGRAGVPMEVMGLMLGDFVDEYTVRVVDVFAMPQSgtgvSVEAVDPVFQTKM--MdflKQTGRPESVVGWYHSHPGFGCWLSSVDINTQQ 135
                 5789*********************7777777777665444488553333344444444..3559******************98777777776665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (336 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       809  (0.0451224); expected 358.6 (0.02)
Passed bias filter:                      495  (0.0276089); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.69u 0.34s 00:00:01.03 Elapsed: 00:00:00.59
# Mc/sec: 1725.52
//
Query:       EEA20875.1  [L=548]
Description: mitochondrial translocase complex component (Tim50), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-41  141.2   0.0    3.1e-41  140.7   0.0    1.2  1  NIF       NLI interacting factor-like phosphatase
  ------ inclusion threshold ------
        7.3    4.8   6.5         12    4.1   6.5    1.2  1  Menin     Menin


Domain annotation for each model (and alignments):
>> NIF  NLI interacting factor-like phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.7   0.0   3.5e-45   3.1e-41       1     156 []     271     418 ..     271     418 .. 0.97

  Alignments for each domain:
  == domain 1  score: 140.7 bits;  conditional E-value: 3.5e-45
         NIF   1 ktLVLDLDetLvhsklekskklkvegekvevsvlkRpgldefLkelsklyevvifTasseeyaeavidildpekkllshrlyrescvkkkgeyvKdLsl 99 
                 +tLVL L+++Lvhs++         +++++++v+kRpg+d+fL++l+++ye+v+fT+  + +a++v+++ldp +  +   l+re+++ k+geyvKdLs+
  EEA20875.1 271 YTLVLSLEDLLVHSEW---------TREHGWRVAKRPGVDYFLRYLNQYYELVLFTSVPSMMADQVLRKLDPFRI-IRWPLFREATKYKDGEYVKDLSY 359
                 79*************9.........99**********************************************96.9999******877********** PP

         NIF 100 lgrdlsrvvivDdspdsfelqpengipiksffsdkkDneLlkllpllkela..kvddvr 156
                 l+rdls+v+++D  p  ++ qpen+i  +++ +d kD++L  l+p+l+ +a  +v+dvr
  EEA20875.1 360 LNRDLSKVILIDTVPGHAREQPENAIILPKWKGDTKDKSLVALIPFLEYVAgmNVEDVR 418
                 ************************************************99986679997 PP

>> Menin  Menin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   6.5    0.0013        12     524     597 ..      45     118 ..      28     134 .. 0.69

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.0013
       Menin 524 aeqkqkkageeserreannnnnsksnsekeadkkasttsnggeasstpsseseaavespsehkeakleeksqel 597
                  +qk k a ++++++++n   +s+ +++k   +   tts+++ a s++s+ s++a e+p+++ +   e+ + e+
  EEA20875.1  45 PNQKAKPAQSKATPSQKNTSTKSQPTQQKSKPTVVGTTSKAKAAASASSGASTNASETPKSEPDVSPEQPEFET 118
                 46677777777777777777777777777777889999999999999999999999999886665555444222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (548 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1327  (0.0740142); expected 358.6 (0.02)
Passed bias filter:                      599  (0.0334096); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.84u 0.39s 00:00:01.23 Elapsed: 00:00:00.57
# Mc/sec: 2911.06
//
Query:       EEA20876.1  [L=310]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (310 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       357  (0.0199119); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.47
# Mc/sec: 1968.23
//
Query:       EEA20877.1  [L=446]
Description: L-allo-threonine aldolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.8e-68  231.0   0.0    2.4e-68  230.6   0.0    1.2  1  Beta_elim_lyase  Beta-eliminating lyase


Domain annotation for each model (and alignments):
>> Beta_elim_lyase  Beta-eliminating lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  230.6   0.0   1.3e-72   2.4e-68       1     290 [.      87     378 ..      87     381 .. 0.96

  Alignments for each domain:
  == domain 1  score: 230.6 bits;  conditional E-value: 1.3e-72
                      E-S-GGG----HHHHHHHHCS----CCCT..--HHHHHHHHHHHHHTT-SEEEEES-HHHHHHHHHHHH-.-TTEEEEEETT-HHHHSSTTHHH CS
  Beta_elim_lyase   1 DLlSDsvtkgteamsdaqaaamlGdesYg..edktvnrLedavaelfgkeaalfvpqGtaAnsillkill.qrgeevivtepahihfdetgaia 91 
                      D++SD+vt +t  m++a+++    d+ Y   +d++vnrL++++ el+gkeaa+ + +Gt++n+i+l+++l q+ + v+++ +ah+h +etga+ 
       EEA20877.1  87 DFRSDTVTVPTVHMMQAMIESSFQDDMYDatGDESVNRLQQRLVELTGKEAAMWALSGTMGNQICLRTHLtQPPHTVLLDYRAHVHCWETGAMP 180
                      9*****************99999999985448***********************************9999*********************** PP

                      HCC--EEEEE-EBTTTBE-HHHHHHHS--S-T.TS-EEEEEEEESSBTTTTTB---HHHHHHHHHHHHHCT.......-EEEEEETTHHHHHHH CS
  Beta_elim_lyase  92 elagvklrdlknkeaGkmdlekleaaikevga.heekiklisltvTnntagGqvvsleelrevaaiakkyg.......iplhlDgARfanaaks 177
                      +++++ ++++  k+   ++le+++++i ++g+ h+++++++sl++      G++++l+  +e+++++++         i +hlDgAR+++a+++
       EEA20877.1 181 VMSQAAVTQVHPKNGLHLTLEDVKKHIIADGNiHFPPTRVVSLENSLS---GTILPLKDAKEISDFVRNFPveegekpIAMHLDGARLFDAVAA 271
                      **************88*************999*************999...****************97555556777**************** PP

                      HTS-CHHHHTTSSEEEEESSSTT--SS-EEEEE-HH....HHHHHHHHHHHHT---SSTHHHHH..HHHHHHHHSSTTHHHHHHHHHHHHHHHH CS
  Beta_elim_lyase 178 lgeivkemfsyvDsvtmslkKdllanvGgvlafrddeledylaerveqrkylggglrqagvlaaleagiraleeglaslerdhktaeqlaekle 271
                       g+++ke+++++Ds++++l K+l+a++G++++++++    ++ +++ +rk+ ggg rq g++aa  a+++ale  + +l + h+ +++ a+ l+
       EEA20877.1 272 EGVSLKEYCACFDSISICLAKGLGAPMGSIIVGSKK----FIHRARLFRKMFGGGTRQPGMMAA--AALCALEYTMPLLPKVHALTKRTADSLR 359
                      ************************************....************************..**************************** PP

                      HCT--EEECCGTTCCEEEE CS
  Beta_elim_lyase 272 lvrlaiprrvytqehldyv 290
                      +  + i  +v+t++ ++++
       EEA20877.1 360 EAGYKITLPVQTNMIVLDL 378
                      **********999888766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (446 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       461  (0.0257125); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.23s 00:00:00.74 Elapsed: 00:00:00.39
# Mc/sec: 3410.66
//
Query:       EEA20878.1  [L=339]
Description: L-allo-threonine aldolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.1e-60  203.6   0.0    5.3e-60  203.2   0.0    1.1  1  Beta_elim_lyase  Beta-eliminating lyase


Domain annotation for each model (and alignments):
>> Beta_elim_lyase  Beta-eliminating lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  203.2   0.0     3e-64   5.3e-60       1     237 [.      87     327 ..      87     337 .. 0.95

  Alignments for each domain:
  == domain 1  score: 203.2 bits;  conditional E-value: 3e-64
                      E-S-GGG----HHHHHHHHCS----CCCT..--HHHHHHHHHHHHHTT-SEEEEES-HHHHHHHHHHHH-.-TTEEEEEETT-HHHHSSTTHHH CS
  Beta_elim_lyase   1 DLlSDsvtkgteamsdaqaaamlGdesYg..edktvnrLedavaelfgkeaalfvpqGtaAnsillkill.qrgeevivtepahihfdetgaia 91 
                      D++SD+vt +t  m++a+++    d+ Y   +d++vnrL++++ el+gkeaa+ + +Gt++n+i+l+++l q+ + v+++ +ah+h +etga+ 
       EEA20878.1  87 DFRSDTVTVPTVHMMQAMIESSFQDDMYDatGDESVNRLQQRLVELTGKEAAMWALSGTMGNQICLRTHLtQPPHTVLLDYRAHVHCWETGAMP 180
                      9*****************99999999985448***********************************9999*********************** PP

                      HCC--EEEEE-EBTTTBE-HHHHHHHS--S-T.TS-EEEEEEEESSBTTTTTB---HHHHHHHHHHHHHCT.......-EEEEEETTHHHHHHH CS
  Beta_elim_lyase  92 elagvklrdlknkeaGkmdlekleaaikevga.heekiklisltvTnntagGqvvsleelrevaaiakkyg.......iplhlDgARfanaaks 177
                      +++++ ++++  k+   ++le+++++i ++g+ h+++++++sl++      G++++l+  +e+++++++         i +hlDgAR+++a+++
       EEA20878.1 181 VMSQAAVTQVHPKNGLHLTLEDVKKHIIADGNiHFPPTRVVSLENSLS---GTILPLKDAKEISDFVRNFPveegekpIAMHLDGARLFDAVAA 271
                      **************88*************999*************999...****************97555556777**************** PP

                      HTS-CHHHHTTSSEEEEESSSTT--SS-EEEEE-HH....HHHHHHHHHHHHT---SSTH CS
  Beta_elim_lyase 178 lgeivkemfsyvDsvtmslkKdllanvGgvlafrddeledylaerveqrkylggglrqag 237
                       g+++ke+++++Ds++++l K+l+a++G++++++++    ++ +++ +rk+ ggg rq+ 
       EEA20878.1 272 EGVSLKEYCACFDSISICLAKGLGAPMGSIIVGSKK----FIHRARLFRKMFGGGTRQVC 327
                      ************************************....****************9975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (339 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       634  (0.0353617); expected 358.6 (0.02)
Passed bias filter:                      556  (0.0310112); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.40
# Mc/sec: 2528.50
//
Query:       EEA20879.1  [L=343]
Description: L-allo-threonine aldolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.3e-60  203.8   0.0    4.2e-60  203.5   0.0    1.1  1  Beta_elim_lyase  Beta-eliminating lyase


Domain annotation for each model (and alignments):
>> Beta_elim_lyase  Beta-eliminating lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  203.5   0.0   2.3e-64   4.2e-60      25     290 ..       8     275 ..       1     278 [. 0.94

  Alignments for each domain:
  == domain 1  score: 203.5 bits;  conditional E-value: 2.3e-64
                      -CCCT..--HHHHHHHHHHHHHTT-SEEEEES-HHHHHHHHHHHH-.-TTEEEEEETT-HHHHSSTTHHHHCC--EEEEE-EBTTTBE-HHHHH CS
  Beta_elim_lyase  25 desYg..edktvnrLedavaelfgkeaalfvpqGtaAnsillkill.qrgeevivtepahihfdetgaiaelagvklrdlknkeaGkmdlekle 115
                      d+ Y   +d++vnrL++++ el+gkeaa+ + +Gt++n+i+l+++l q+ + v+++ +ah+h +etga+ +++++ ++++  k+   ++le+++
       EEA20879.1   8 DDMYDatGDESVNRLQQRLVELTGKEAAMWALSGTMGNQICLRTHLtQPPHTVLLDYRAHVHCWETGAMPVMSQAAVTQVHPKNGLHLTLEDVK 101
                      565542289**********************************9999*************************************88******** PP

                      HHS--S-T.TS-EEEEEEEESSBTTTTTB---HHHHHHHHHHHHHCT.......-EEEEEETTHHHHHHHHTS-CHHHHTTSSEEEEESSSTT- CS
  Beta_elim_lyase 116 aaikevga.heekiklisltvTnntagGqvvsleelrevaaiakkyg.......iplhlDgARfanaakslgeivkemfsyvDsvtmslkKdll 201
                      ++i ++g+ h+++++++sl++      G++++l+  +e+++++++         i +hlDgAR+++a+++ g+++ke+++++Ds++++l K+l+
       EEA20879.1 102 KHIIADGNiHFPPTRVVSLENSLS---GTILPLKDAKEISDFVRNFPveegekpIAMHLDGARLFDAVAAEGVSLKEYCACFDSISICLAKGLG 192
                      *****999*************999...****************97555556777**************************************** PP

                      -SS-EEEEE-HH....HHHHHHHHHHHHT---SSTHHHHH..HHHHHHHHSSTTHHHHHHHHHHHHHHHHHCT--EEECCGTTCCEEEE CS
  Beta_elim_lyase 202 anvGgvlafrddeledylaerveqrkylggglrqagvlaaleagiraleeglaslerdhktaeqlaeklelvrlaiprrvytqehldyv 290
                      a++G++++++++    ++ +++ +rk+ ggg rq g++aa  a+++ale  + +l + h+ +++ a+ l++  + i  +v+t++ ++++
       EEA20879.1 193 APMGSIIVGSKK----FIHRARLFRKMFGGGTRQPGMMAA--AALCALEYTMPLLPKVHALTKRTADSLREAGYKITLPVQTNMIVLDL 275
                      ************....************************..**************************************999888766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (343 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       350  (0.0195214); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.46
# Mc/sec: 2264.54
//
Query:       EEA20880.1  [L=695]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.1e-14   52.2   0.0    7.5e-14   51.4   0.0    1.4  1  Fungal_trans  Fungal specific transcription factor domain
    1.2e-06   28.5   6.7      3e-06   27.2   6.7    1.7  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.4   0.0   8.3e-18   7.5e-14       3     265 ..     230     460 ..     228     462 .. 0.81

  Alignments for each domain:
  == domain 1  score: 51.4 bits;  conditional E-value: 8.3e-18
  Fungal_trans   3 rffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeili....hedfsspssslwilq 95 
                   +f + f+  fp+++ + f++ +     s+++  ++ ll  ++a+   +++ + k+   ++ +++   i         +    hed+s p    +++ 
    EEA20880.1 230 LFIDRFNVAFPVFDGQAFWEAY----ISDADDLPTTLLCHVYAMSLVYWKHTPKFARHPKPDVR-YAINL-------TvaalHEDYSAPGL-STVSA 313
                   79999*****************....99999************************988888877.44433.......233449********.99999 PP

  Fungal_trans  96 sLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddl 192
                   +Ll l    + s + ++    +g  v+la+ lgL+r+ps+++      ++  ++++r Rlww++ + D++ ++ +G pp +++sq ++pLP  +  +
    EEA20880.1 314 ALLDLTGRPIFSMTGNAI--SCGRLVSLAHCLGLNRDPSNWK------VPLSDKKQRIRLWWGVVIQDRWGSFGHGVPPQISKSQYDVPLPSVEVLV 402
                   999999999888874444..579999999*************......99999**************************99**********999988 PP

  Fungal_trans 193 wesddaseetlvetklsneeksrkiasfllaLkkilskiagsllsiekqlqqrdlqseklswveeleraldnW 265
                    +   +s++ +  +             +l +L +il++++     + +qlq +  + e+ + ++ +++ ld+W
    EEA20880.1 403 TQPRATSQHIRAAHC----------HISLCRLTEILGELLP----LVYQLQTKPGR-ENSKRLRHIRTDLDTW 460
                   888888888887732..........3345555555555555....44444444444.4447888888899988 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.2   6.7   3.4e-10     3e-06       1      37 [.      33      70 ..      33      73 .. 0.90

  Alignments for each domain:
  == domain 1  score: 27.2 bits;  conditional E-value: 3.4e-10
                SS-HHHHHCT---STSSSS..-HHHHHCTHHHCCCCTCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPa..CsnCkklnleCtfysess 37
                +aCd Crk+K++C  ++P   C  C+  +++C  y+e s
  EEA20880.1 33 RACDLCRKRKSRCTVDIPGqsCVLCRIQGADCH-YQEDS 70
                69****************999************.87765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (695 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       501  (0.0279436); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.31s 00:00:00.93 Elapsed: 00:00:00.46
# Mc/sec: 4516.43
//
Query:       EEA20881.1  [L=1016]
Description: F-box domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.083   13.8   1.2         55    4.9   0.0    4.0  4  WD40      WD domain, G-beta repeat
        0.1   12.5   0.0       0.23   11.4   0.0    1.6  1  F-box     F-box domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0      0.11   9.4e+02       5      36 ..     205     246 ..     201     247 .. 0.67
   2 ?    3.4   0.1     0.018   1.6e+02      14      31 ..     267     284 ..     258     285 .. 0.77
   3 ?    4.9   0.0    0.0062        55      18      37 ..     336     353 ..     323     354 .. 0.89
   4 ?   -2.7   0.0       1.6   1.4e+04      17      32 ..     864     885 ..     831     887 .. 0.56

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.11
                 EEEESS..SS........E.EEEEEETTSSEEEEE.ETTSEEEE CS
        WD40   5 rtltGH..ss........v.tslafspdgawlasG.sdDgtvri 36 
                 ++l+ H  ++        v ++la  p+g+ l  G  +Dg++ +
  EEA20881.1 205 YHLSRHeaKHvqvltlndVpRALALAPNGSVL--GiAYDGSIEV 246
                 5666665444554444446678899*****98..6655999975 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.018
                 EEEEEETTSSEEEEEETT CS
        WD40  14 tslafspdgawlasGsdD 31 
                   l+fspdg++l+ +s D
  EEA20881.1 267 DTLSFSPDGSMLLGSSLD 284
                 5689********944545 PP

  == domain 3  score: 4.9 bits;  conditional E-value: 0.0062
                 EETTSSEEEEEETTSEEEEE CS
        WD40  18 fspdgawlasGsdDgtvriW 37 
                  s d +w++ G  D+t++i+
  EEA20881.1 336 ISGDDDWVM-GY-DNTLKIF 353
                 5899****9.**.*****97 PP

  == domain 4  score: -2.7 bits;  conditional E-value: 1.6
                 E.......EETTSSEEEEEETTS CS
        WD40  17 a.......fspdgawlasGsdDg 32 
                 +       fs++++ la G+ +g
  EEA20881.1 864 KsimgngrFSRSSPNLAIGG-NG 885
                 04444444777778788787.66 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   2.6e-05      0.23       5      44 ..      30      69 ..      27      73 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 2.6e-05
                HS-HHHHHHHHHTS-HHHHHHHCTT-HHHHHHHTTHHHHH CS
       F-box  5 rLPsevlrhILerLplsdllalrrVSkgwrilidsdrlwc 44
                rLP+ v+r++L  ++  +  +l+     wr++ ++ +l+ 
  EEA20881.1 30 RLPLNVIRKVLYTVDANTFASLAILNEQWRQASNDAELYA 69
                9*******************************99988876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1016 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       822  (0.0458475); expected 358.6 (0.02)
Passed bias filter:                      395  (0.0220313); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.72u 0.29s 00:00:01.01 Elapsed: 00:00:00.47
# Mc/sec: 6546.32
//
Query:       EEA20882.1  [L=767]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.2e-19   70.5   0.7    2.6e-13   50.8   0.1    2.7  2  GRDP-like  Glycine-rich domain-containing protein-like


Domain annotation for each model (and alignments):
>> GRDP-like  Glycine-rich domain-containing protein-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.1   3.2e-07    0.0058     119     142 .]     177     200 ..     160     200 .. 0.81
   2 !   50.8   0.1   1.5e-17   2.6e-13      33     140 ..     392     505 ..     380     506 .. 0.79

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 3.2e-07
   GRDP-like 119 lvPtyDidLiWhtHqlhpisYakD 142
                   P +D+ ++Wh+H l+p +Y +D
  EEA20882.1 177 SLPPLDVLMVWHAHLLNPRTYLED 200
                 6899*****************998 PP

  == domain 2  score: 50.8 bits;  conditional E-value: 1.5e-17
   GRDP-like  33 elwkrlypeepf..ele.skklkkeeevsessss...isydlvkavkrqskfvykvs......sphiseevflkeAvqRYkrfLyLlkkneeegskrfl 119
                 +++++   + ++   l+ ++++++++ +s++ ++      dlv+av rq +f++k++      sp +  +  +++ ++ Y  f++++  n+    +++ 
  EEA20882.1 392 KVLMTINGNSRYshRLKrEQRISIRRMMSHYWENssiFGLDLVGAVIRQGTFIQKMDnldwihSPAVAAT--MDRLIRKYGIFFQIMISNA----NQMA 484
                 5666777777773334444555544444444333445889*****************9999999999999..9999999**********99....5679 PP

   GRDP-like 120 vPtyDidLiWhtHqlhpisYa 140
                 vPt+D+dL WhtHq++p  Y+
  EEA20882.1 485 VPTLDVDLAWHTHQMSPARYF 505
                 ********************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (767 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       771  (0.043003); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.30s 00:00:00.95 Elapsed: 00:00:00.46
# Mc/sec: 4966.64
//
Query:       EEA20883.1  [L=736]
Description: C6 transcription factor (Leu3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.4e-10   38.0   0.3    1.7e-09   37.1   0.3    1.4  1  Fungal_trans  Fungal specific transcription factor domain
    1.3e-06   28.4   9.6    1.3e-06   28.4   9.6    1.7  2  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.061   13.1   0.1       0.14   11.9   0.1    1.6  1  DivIC         Septum formation initiator
        9.6    6.6   8.3        1.5    9.2   0.6    2.9  4  NUDE_C        NUDE protein, C-terminal conserved region


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.1   0.3   3.8e-13   1.7e-09       2     178 ..     219     380 ..     218     398 .. 0.79

  Alignments for each domain:
  == domain 1  score: 37.1 bits;  conditional E-value: 3.8e-13
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLl 98 
                   ++ff+ +hp +p+l+++   +++        + +spll+++i+++Ga+  +++++  ns +  +        l ++++      + ++s++++++L 
    EEA20883.1 219 NLFFTFYHPYLPFLDREVTPEEY--------YTTSPLLFWMIISVGARRYQTDAQLLNSLAGPVT------RLVWSTIA-----DIPQSFHAVKALC 296
                   58**************9999999........899**************99999988755555433......33555444.....555559******* PP

  Fungal_trans  99 llelyektssdralher..hhgvavrlarslgLhrnpsyvgkkslwklweeeaesrr..RlwwaaFylDktialklGrpp.lldd 178
                   ll+++ + +s+++      ++g++v++a +lgLhr +      s +++   e+e r   R+w  + ++  ++a+ +G pp +l+d
    EEA20883.1 297 LLCTWPFPTSSTSTDPTfmLSGLMVHVAMQLGLHRPSHTQD-FSKFRVELIESELRDkvRTWAICNVVAQRVATGYGQPPsTLYD 380
                   **********988877777***************8776665.4445555554777542378888888888888888888876666 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.4   9.6   2.9e-10   1.3e-06       1      35 [.      66     102 ..      66     107 .. 0.86
   2 ?   -3.0   0.1       1.9   8.4e+03       9      14 ..     603     608 ..     602     610 .. 0.76

  Alignments for each domain:
  == domain 1  score: 28.4 bits;  conditional E-value: 2.9e-10
                 SS-HHHHHCT---ST.SSSS..-HHHHHCTHHHCCCCT CS
     Zn_clus   1 haCdnCrkkKvKCda.kkPa..CsnCkklnleCtfyse 35 
                 +aC++Cr++K +Cd  + P   Cs+C++l leC+ ++ 
  EEA20883.1  66 RACNECRQQKLRCDViQEPFmdCSRCRRLKLECK-IES 102
                 69*************8888799***********9.443 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.9
                 CT---S CS
     Zn_clus   9 kKvKCd 14 
                  Kv+C 
  EEA20883.1 603 LKVRCR 608
                 699997 PP

>> DivIC  Septum formation initiator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.1   3.1e-05      0.14      18      57 ..     112     151 ..     107     153 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 3.1e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC-XXXXXXX CS
       DivIC  18 aykqlkqeiaalqaelaklkaeneeLeaevkdLksdedyi 57 
                 +  ++++ei +l +++a+ +a+n++ +++v   k+d ++i
  EEA20883.1 112 RNAEMEREIIELRRQIANANATNASFKSQVTPVKQDASAI 151
                 66789****************************9999998 PP

>> NUDE_C  NUDE protein, C-terminal conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.1     0.088   3.9e+02     113     129 ..       4      20 ..       1      36 [. 0.78
   2 ?    9.2   0.6   0.00034       1.5      21     129 ..      48     169 ..      47     213 .. 0.64
   3 ?   -3.2   0.1       2.3     1e+04     117     141 ..     583     607 ..     562     643 .. 0.59
   4 ?   -3.6   0.1       2.9   1.3e+04      69      95 ..     632     659 ..     617     686 .. 0.58

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.088
      NUDE_C 113 gsetatppsPpasessd 129
                  s++atp++ p+++ ++
  EEA20883.1   4 ESQNATPLTSPVRINAK 20 
                 4899**********983 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00034
      NUDE_C  21 eeikagEqErEsLrievQRLrDelsDLkveleiiqeklrkaeeklrrrkplslsspstpqsleiekrspavqas.......ssPviatppekslsslat 112
                 +ei  g+q  E+ r  v R  +e + +k+  ++iqe   +  +  r + +  ++s  +   +  ++++++ +             ++ + +++++ +++
  EEA20883.1  48 DEIDDGDQHEERKRQPVKRACNECRQQKLRCDVIQEPFMDCSRCRRLKLECKIESNFKRVGKRSRNAEMEREIIelrrqiaNANATNASFKSQVTPVKQ 146
                 589999*******************************99988887767676662222221111122222222213332222333333444444444444 PP

      NUDE_C 113 g.setatppsPpasess.....d 129
                   s+++tp+s ++ +++     d
  EEA20883.1 147 DaSAISTPLSGAMYQTPtplstD 169
                 45888999999888887444442 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 2.3
      NUDE_C 117 atppsP.pasessdllrkvlaltskl 141
                 +  p+P pas ss +++  l+l+   
  EEA20883.1 583 GGAPTPrPASASS-EIDDQLQLKVRC 607
                 3444442555555.444444444333 PP

  == domain 4  score: -3.6 bits;  conditional E-value: 2.9
      NUDE_C  69 kplslsspstp.qsleiekrspavqass 95 
                  + sl++p+ p ++ +++    +  ass
  EEA20883.1 632 IEASLKNPTDPdSNGDTTGSALGPRASS 659
                 4455566666644444444444444432 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (736 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       634  (0.0353617); expected 358.6 (0.02)
Passed bias filter:                      479  (0.0267165); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.64u 0.28s 00:00:00.92 Elapsed: 00:00:00.43
# Mc/sec: 5186.53
//
Query:       EEA20884.1  [L=452]
Description: deoxyribodipyrimidine photo-lyase Phr1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      2e-20   73.5   1.8      2e-20   73.5   1.8    2.2  2  DNA_photolyase  DNA photolyase


Domain annotation for each model (and alignments):
>> DNA_photolyase  DNA photolyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.1      0.49   8.7e+03      77     110 ..     154     187 ..     150     194 .. 0.56
   2 !   73.5   1.8   1.1e-24     2e-20       1     124 [.     327     442 ..     327     445 .. 0.91

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 0.49
                     HHHHHHHHHHCTECEEEEE---SHHHHHHHHHHH CS
  DNA_photolyase  77 advlpelakelgasavvanreyepdererdeavk 110
                     +d+l+e  ++ ++++  a+++y + + + + +v+
      EEA20884.1 154 RDILAESNTQREVRRRAAQTDYGSMAIRDRMNVR 187
                     4555555555555555666666666655555555 PP

  == domain 2  score: 73.5 bits;  conditional E-value: 1.1e-24
                     EEEEESS---STT-HHHHHHHCTTSEEEEEEEE-HHHHTCGS-CHHHHHHHHHHHHHHHHHHHHTT--EEEEESS....HHHHHHHHHHHCTECE CS
  DNA_photolyase   1 vlvWfrrDlRlhDNpALaaAaasgepvipvfvldpekahklrvgaarvdfllesLadLdeeLrelgirLvvrrgd....padvlpelakelgasa 91 
                     vl+Wf+ DlRl+DN+AL+ A + +++        ++    +  ++arvdf+l++L+ L+++L++l+i+L++ + +    +   ++el++++gas+
      EEA20884.1 327 VLHWFKGDLRLKDNRALTMASELAAK--------NN----IVRCPARVDFTLRNLKVLQQKLDNLDIPLYMETQEqrrnVPGRIAELCERWGASH 409
                     79******************887642........22....245899***************************997888888889********** PP

                     EEEE---SHHHHHHHHHHHHHHHHCTSEEEEE- CS
  DNA_photolyase  92 vvanreyepdererdeavkealrkagievesfd 124
                     ++an eye+de +r++++ + ++++g+++e+ +
      EEA20884.1 410 LFANIEYEVDELRRKAKLVRLFADKGVAFETRW 442
                     ****************************99765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (452 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1069  (0.0596241); expected 358.6 (0.02)
Passed bias filter:                      532  (0.0296726); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.27s 00:00:00.88 Elapsed: 00:00:00.45
# Mc/sec: 3029.84
//
Query:       EEA20885.1  [L=592]
Description: sugar transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-34  119.8  43.3    3.5e-29  101.9  26.4    2.1  2  MFS_1     Major Facilitator Superfamily
    6.5e-18   64.8  23.7    1.2e-16   60.7  23.6    2.8  1  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.9  26.4   3.9e-33   3.5e-29      13     353 .]     135     550 ..     121     550 .. 0.83
   2 !   32.2   8.8   5.6e-12     5e-08      42     175 ..     452     585 ..     448     591 .. 0.79

  Alignments for each domain:
  == domain 1  score: 101.9 bits;  conditional E-value: 3.9e-33
       MFS_1  13 silgpalpl.alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlgagalfpagaal 109
                 ++ g+al+l  +++++gis + + + +++ ++g ++++ ++G  sd +Grr  + ++l++ ++++++++ as+ w  ++ l + +Glg g+ +p+ +al
  EEA20885.1 135 WLQGIALTLnQVSQEFGISDTHVRFTTAALFIGLCLGASFWGIASDVVGRRFAFNMTLFICGIFGIFIA-ASPTWiGVCGLAAAMGLGVGGNLPVDGAL 232
                 336677777799****************************************99999999999966666.4999999********************** PP

       MFS_1 110 iadwfpkeergraigllsagfslGailgpllggllasslg.........................Wravfyilaivsllafvlfllllpeepperkrks 183
                 + +  p  e g  + lls+ + +G ++g l++  ++ +++                         Wr++ + l++++l +fv+ ++l+   ++++   s
  EEA20885.1 233 FLEFLPF-ESGNLLTLLSVWWPVGQLVGSLIAWGFIPNYSceaglpacsavaageaccrrednmgWRYLCLTLGAITLAMFVCRFFLFHLYESPKFLLS 330
                 *******.**************************************************************************86677755555555555 PP

       MFS_1 184 pkeee.................................................kgtgpaplvp..........awkallkdpvlwillialllfffgf 223
                   ++e                                                 +        +          + k l    vl  l+++++++++g+
  EEA20885.1 331 RGRQEeavrtvhaiayknkaktwltvdilneigghpgdgddakltrfeiikrslS--------KfsaerlcplfHTKRLGITTVL--LWFCWATIGMGY 419
                 5555556777777777777777799999999999999999966666444443331........2333333333335555555555..************ PP

       MFS_1 224 sglltllplylqevlgls...glllaglllallalvgailallagrlsdr..lgrrrrlllallllllaalglallavtssavllllvlvliGfglgfv 317
                  ++ ++lp y   + g +      +++  +a++++vg+++++++ + ++   +g  r  ++a++ ++++ ++++++    ++ + ll + l +f++ ++
  EEA20885.1 420 PLFNAFLPQY-LAHAGSGtvtPINITYRNYAITSIVGVPGSIIGCYTVNIkyIG--RKGTMAIATMFTGIILFCFTVSN-DSNIQLLCSSLESFFQNIM 514
                 **********.7788888899445555558999999999999999999884455..57888888888888888888888.557777789999******* PP

       MFS_1 318 fpsllalasdlappeeagtasglfntagslggalgp 353
                 ++ l a++ +++p+ ++g+ +g++++++ l g+++p
  EEA20885.1 515 YGVLYAYTPEVFPAPNRGSGTGIASFFNRLCGVMAP 550
                 ********************************9998 PP

  == domain 2  score: 32.2 bits;  conditional E-value: 5.6e-12
       MFS_1  42 algaavaslplGrlsdr..fGrrrvlllglllfalglllllfasslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailg 137
                 +++ + +s+++ + ++   +Gr+ ++ ++  ++++ l+++++ s+   + l++  l ++++ +++ + +a++ ++fp ++rg+++g++s ++ l  +++
  EEA20885.1 452 SIVGVPGSIIGCYTVNIkyIGRKGTMAIATMFTGIILFCFTV-SNDSnIQLLCSSLESFFQNIMYGVLYAYTPEVFPAPNRGSGTGIASFFNRLCGVMA 549
                 556666666776665533379999999999999999555555.88888*************************************************** PP

       MFS_1 138 pllggllasslgWravfyilaivsllafv.lfllllpee 175
                 p+++ + a + + +a+ y+ +++ l af  +  ++lp e
  EEA20885.1 550 PIVAIYGAKN-NASAPVYASGGLILAAFGaM--VFLPIE 585
                 *****99944.56677777777777774413..666655 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.7  23.6   1.3e-20   1.2e-16      44     443 ..     153     589 ..      79     591 .. 0.77

  Alignments for each domain:
  == domain 1  score: 60.7 bits;  conditional E-value: 1.3e-20
                 ...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHH CS
    Sugar_tr  44 ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvsl 142
                 s++ + ++++++++G  +G+ f g+++d++GR+ ++ ++ +++ i ++ +aa++   ++  ++     +G+gvG+   +   +  E+ p +  g l +l
  EEA20885.1 153 SDTHVRFTTAALFIGLCLGASFWGIASDVVGRRFAFNMTLFICGIFGIFIAASP---TWIGVCGLAAAMGLGVGGNLPVDGALFLEFLPFE-SGNLLTL 247
                 56667799**********************************************...89999999***********************998.79***** PP

                 HHHHHHHHHHHHHHHHHHH.HTSS-......................TTHHHHHHHCCHHHHHHHHHHGGG...S---HHHHHHTT-HHHHHHHHHHHH CS
    Sugar_tr 143 yqlaitfGilvaaifglgl.nktsn......................adgwrillglqlvpallllilllf...lPESPrylvekgkeeeakevlaklr 215
                   +++ +G+lv++ + +g+   + +                      + gwr+l+    +++l+++++++f   l ESP +l+++g++eea +++  + 
  EEA20885.1 248 LSVWWPVGQLVGSLIAWGFiP-NYSceaglpacsavaageaccrredNMGWRYLCLTLGAITLAMFVCRFFlfhLYESPKFLLSRGRQEEAVRTVHAIA 345
                 *******************53.444479******************999****************99887733358***************99999955 PP

                 HC...................HHHHHHHHHHHHHHHHHHH.....................HTTHHHHSH...HHHHHHHHHHH..HHHTTHHHHHHHT CS
    Sugar_tr 216 ge...................edadrelaeekdsleaeqeee................kaswkellssktvrqrlligvvlqif..qqltGinaimyys 277
                  +                                                        k s ++l   +  ++  ++ v+l+++  +   G+  +  + 
  EEA20885.1 346 YKnkaktwltvdilneigghpG--------------D----GddakltrfeiikrslsKFSAERLCPLFHTKRLGITTVLLWFCwaTIGMGYPLFNAFL 426
                 5522333333333333333331..............2....13333666666633333334444444433333334445555432256678889999** PP

                 TTHHHHSS-THH......HHHHHHHHHHHHHHHHHHHHHH..HHS-SHHHHHHHHHHHHHHHHHHH...HHHHTTSS...CHHHHHHHHHHHHHHHTTT CS
    Sugar_tr 278 ptifenlglsks......llvtiivgvvnfvatfvaiflv..drfGRRtllllGaagmaicfvilg.ivalllvakskaasivaivfialfialfalgw 367
                 p+ +  +g  +       +   +i+++v +  ++++ ++v  +++GR+        +mai++++ g i ++++v+++   s++ + +  l   +f+  +
  EEA20885.1 427 PQYLAHAGSGTVtpinitYRNYAITSIVGVPGSIIGCYTVniKYIGRK-------GTMAIATMFTGiILFCFTVSND---SNIQLLCSSLE-SFFQNIM 514
                 *********99977766433446788888888899987753379****.......5566666666656777777776...77777777666.6777788 PP

                 THHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT- CS
    Sugar_tr 368 gpvpwvlvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgr 443
                  +v++ + +E+fp   R++++ ia + n l+ +   ++  + +++   ++v++  + ++ +++  ++f  +et g+
  EEA20885.1 515 YGVLYAYTPEVFPAPNRGSGTGIASFFNRLCGVMAPIVAIYGAKNNASAPVYASGGLIL-AAFGAMVFLPIETRGK 589
                 88999***************************************999899987655555.5555556666777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (592 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       581  (0.0324056); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.26s 00:00:00.89 Elapsed: 00:00:00.44
# Mc/sec: 4045.36
//
Query:       EEA20886.1  [L=447]
Description: hypothetical protein PMAA_047010 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
     0.0089   15.6  22.7      0.066   12.8   0.3    5.4  4  PI3K_P85_iSH2    Phosphatidylinositol 3-kinase regulatory sub
  ------ inclusion threshold ------
      0.042   14.1   4.2      0.071   13.4   0.1    3.3  4  Imm7             Immunity protein 7
      0.047   13.7  23.6       0.12   12.5   2.8    4.9  4  DUF1664          Protein of unknown function (DUF1664)
       0.16   12.4  30.0        3.3    8.2   0.0    6.1  4  ZapB             Cell division protein ZapB
       0.18   11.9  25.7       0.18   11.8   2.6    4.3  4  ADIP             Afadin- and alpha -actinin-Binding
       0.27   11.7  25.8        2.4    8.7   1.8    6.9  6  NPV_P10          Nucleopolyhedrovirus P10 protein
       0.32   11.3  34.3       0.13   12.6   1.2    6.5  7  DUF4164          Domain of unknown function (DUF4164)
        1.6    9.0  21.5        9.1    6.7   1.1    6.2  6  BLOC1_2          Biogenesis of lysosome-related organelles co
        1.7    8.0  23.1      0.071   12.5   8.2    4.1  4  DUF4618          Domain of unknown function (DUF4618)
          2    8.4   4.3        1.4    8.9   1.0    2.4  2  Methyltransf_32  Methyltransferase domain
        2.4    7.7  22.0        1.3    8.5   3.9    3.1  3  Exonuc_VII_L     Exonuclease VII, large subunit
        2.6    8.2  38.8         18    5.5   2.2    6.1  4  ATG16            Autophagy protein 16 (ATG16)
        3.1    8.3  23.5        2.2    8.7   0.8    6.7  9  FlaC_arch        Flagella accessory protein C (FlaC)
        3.9    8.1  24.3        7.2    7.2   0.0    5.1  5  Syntaxin-6_N     Syntaxin 6, N-terminal
        5.2    6.9  12.4       0.11   12.4   2.3    2.9  3  CK2S             Casein Kinase 2 substrate
        7.1    7.0  16.4        2.5    8.4   0.3    4.5  4  DUF641           Plant protein of unknown function (DUF641)
        8.2    6.1  12.5         31    4.2   0.3    5.2  5  DUF4988          Domain of unknown function


Domain annotation for each model (and alignments):
>> PI3K_P85_iSH2  Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.0   0.8   0.00047       0.5      82     136 ..      26      90 ..      13      92 .. 0.80
   2 !   12.8   0.3   6.3e-05     0.066      80     130 ..     128     178 ..      88     185 .. 0.70
   3 ?    2.3   0.2      0.11   1.1e+02      89     112 ..     254     277 ..     187     297 .. 0.58
   4 ?   -1.9   7.7         2   2.1e+03      54     118 ..     262     328 ..     254     388 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00047
  PI3K_P85_iSH2  82 EieklqenleqlksrlkelhsskekLeedlkqqkeeer..........eleReinalkpellqLq 136
                      e l+++ ++l+sr++ l ++++ L+ +++ +  + +          +++R++ +l+p++  +q
     EEA20886.1  26 SEEGLEQSTSDLQSRVDALLEKMDLLQLQIRLKNGSIQsltgrlevleTVDRKVAQLQPDVFAMQ 90 
                    456899******************99999888877666556667777788999999999988765 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 6.3e-05
  PI3K_P85_iSH2  80 ehEieklqenleqlksrlkelhsskekLeedlkqqkeeereleReinalkp 130
                    + +   ++  ++++ srl+  +  k+ L+ +++ +k + r+leR++nal  
     EEA20886.1 128 NPDRIGIEGEIAEVHSRLDAAQIDKKGLQSQIRLNKGSVRSLERRLNALET 178
                    334446788899***********************************9975 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.11
  PI3K_P85_iSH2  89 nleqlksrlkelhsskekLeedlk 112
                     +++ +s+++ +++ ++ L+ +++
     EEA20886.1 254 AVAEFQSKVEAIEDDRKLLQSQIR 277
                    234455555556666655555555 PP

  == domain 4  score: -1.9 bits;  conditional E-value: 2
  PI3K_P85_iSH2  54 leaFneaikmFeeqiklqekfskea..qehEieklqenleqlksrlkelhsskekLeedlkqqkeee 118
                    +ea ++  k+++ qi+l+   +       +  e+  e+ ++ k+r+++l+s +e+L +   q++++e
     EEA20886.1 262 VEAIEDDRKLLQSQIRLNKGSMVSLagRVKGLESSVEHHREEKNRVDSLESDMEDLIQVTLQRVKRE 328
                    5666666677777777766555554344667777888888888888888888888866544444433 PP

>> Imm7  Immunity protein 7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.1   6.8e-05     0.071       5      54 ..       9      63 ..       7      92 .. 0.73
   2 ?    0.1   0.1      0.86   9.1e+02      18      51 ..     129     164 ..     112     204 .. 0.68
   3 ?   -1.6   0.1         3   3.2e+03      27      46 ..     255     274 ..     236     314 .. 0.63
   4 ?   -2.8   0.0       6.8   7.2e+03      19      32 ..     314     327 ..     294     350 .. 0.55

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 6.8e-05
        Imm7  5 hGWltiqesaee...dddeallesivkeieskideldysselvdL..raknGeyy 54
                +GW+t+ e  +    +  e+ le+  ++++s++d+l  + +l++L  r knG+++
  EEA20886.1  9 DGWATLYEISASsddESSEEGLEQSTSDLQSRVDALLEKMDLLQLqiRLKNGSIQ 63
                69**98775555111444678***************9899988872256899876 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.86
        Imm7  18 ddeallesivkeieskideldysselvd..LraknG 51 
                  d+  +e  ++e++s++d+ +++++ ++  +r   G
  EEA20886.1 129 PDRIGIEGEIAEVHSRLDAAQIDKKGLQsqIRLNKG 164
                 566677888889999988776665554311444444 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 3
        Imm7  27 vkeieskideldysselvdL 46 
                 v+e +sk+++++ + +l++ 
  EEA20886.1 255 VAEFQSKVEAIEDDRKLLQS 274
                 44555555555544444332 PP

  == domain 4  score: -2.8 bits;  conditional E-value: 6.8
        Imm7  19 deallesivkeies 32 
                  e+l++ +++++++
  EEA20886.1 314 MEDLIQVTLQRVKR 327
                 33333444444433 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   2.4     0.097     1e+02      58     111 ..      31      87 ..      18     128 .. 0.46
   2 ?    6.6   1.3     0.007       7.4      63     122 ..     133     193 ..     104     195 .. 0.82
   3 ?    2.6   0.2      0.12   1.3e+02      88     111 ..     254     277 ..     213     304 .. 0.50
   4 ?   12.5   2.8   0.00011      0.12      40     115 ..     304     384 ..     299     388 .. 0.81

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.097
     DUF1664  58 aatkrhLssridrvdkkldeqkeiskeikeevtevredl...seigedvesvkeave 111
                 ++   +L+sr+d + +k+d  +  ++  +  ++++ + l   ++++++v +++  v 
  EEA20886.1  31 EQSTSDLQSRVDALLEKMDLLQLQIRLKNGSIQSLTGRLevlETVDRKVAQLQPDVF 87 
                 444444444444444444433333332222222222222000222222222222222 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.007
     DUF1664  63 hLssridrvdkkldeqkeiskeikeevtevredlseigedvesvk.eavegleskleriee 122
                  ++ +i++v ++ld+ +  +k +++++   ++ ++++++ +++++ + v  le+++er+e 
  EEA20886.1 133 GIEGEIAEVHSRLDAAQIDKKGLQSQIRLNKGSVRSLERRLNALEtNRVDALEASVERVER 193
                 56789***************************************7368**********996 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.12
     DUF1664  88 evtevredlseigedvesvkeave 111
                  v+e ++++++i++d + +++ ++
  EEA20886.1 254 AVAEFQSKVEAIEDDRKLLQSQIR 277
                 233444444444444444443333 PP

  == domain 4  score: 12.5 bits;  conditional E-value: 0.00011
     DUF1664  40 sdavesvskqleqvs.eslaatkrhLssridrvdkkldeqkeiskeikeevtevr....edlseigedvesvkeavegles 115
                 ++ v+s+ +++e++   +l+++kr+ ++r+d+++ + ++ +++  ++++ ++ ++      l +i++d++ +k+ ve les
  EEA20886.1 304 KNRVDSLESDMEDLIqVTLQRVKRENKARMDNLELQNQALQDALGQTQRIIEGLHigiqTALGQINTDLSGLKQRVEMLES 384
                 577889999998865269*****************************9999877611115566888888899999988886 PP

>> ZapB  Cell division protein ZapB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3  11.1       0.9   9.5e+02       8      52 ..      36      83 ..      26     215 .. 0.88
   2 ?    8.2   0.0    0.0032       3.3      12      34 ..     223     245 ..     222     251 .. 0.91
   3 ?    5.6   0.4     0.021        22       9      58 ..     258     307 ..     254     319 .. 0.90
   4 ?    2.2   2.7      0.24   2.5e+02      27      64 ..     322     356 ..     307     370 .. 0.62

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.9
        ZapB  8 qLEskiqkaidtitlLqmeieeLkeeneelkeenrele...eeneqlk 52
                 L+s++++++++++lLq +i+      ++l+ + + le   +++ ql+
  EEA20886.1 36 DLQSRVDALLEKMDLLQLQIRLKNGSIQSLTGRLEVLEtvdRKVAQLQ 83
                699999999999999999998766666777776666666666666666 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.0032
        ZapB  12 kiqkaidtitlLqmeieeLkeen 34 
                 ++++aid++t L   +e+L+++ 
  EEA20886.1 223 RYSQAIDRVTCLEANVERLEQDA 245
                 89*****************9976 PP

  == domain 3  score: 5.6 bits;  conditional E-value: 0.021
        ZapB   9 LEskiqkaidtitlLqmeieeLkeeneelkeenreleeeneqlkeereaw 58 
                  +sk+++  d  +lLq +i+  k    +l+ + + le+++e+ +ee++ +
  EEA20886.1 258 FQSKVEAIEDDRKLLQSQIRLNKGSMVSLAGRVKGLESSVEHHREEKNRV 307
                 6899999999999*********************************9987 PP

  == domain 4  score: 2.2 bits;  conditional E-value: 0.24
        ZapB  27 ieeLkeeneelkeenreleeeneqlkeereawqerlkk 64 
                 ++++k+en   k ++++le +n++l++   ++q+ +++
  EEA20886.1 322 LQRVKREN---KARMDNLELQNQALQDALGQTQRIIEG 356
                 44444444...444446666677776666666665554 PP

>> ADIP  Afadin- and alpha -actinin-Binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   1.0     0.074        78      66     108 ..      24      66 ..      16      83 .. 0.55
   2 ?   11.8   2.6   0.00017      0.18      28     109 ..      97     178 ..      80     200 .. 0.87
   3 ?   -0.7   0.1       1.3   1.3e+03      75      92 ..     180     198 ..     175     247 .. 0.63
   4 ?    6.2   7.2    0.0099        10      44     128 ..     271     357 ..     256     387 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.074
        ADIP  66 eaeierlqskierlktqleqlerelalvqakerqlekklktle 108
                 e++ e l+++++ l+ ++ +l  +++l+q + r  + ++++l+
  EEA20886.1  24 ESSEEGLEQSTSDLQSRVDALLEKMDLLQLQIRLKNGSIQSLT 66 
                 4444555555555555555555555555555554444444444 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 0.00017
        ADIP  28 ekveeniaaiinviysLlqardrdleqreslnetirkleaeierlqskierlktqleqlerelalvqakerqlekklktleq 109
                 e +++  ++ inv+ + +++ + +++  e+ n ++  +e ei+  +s+ +  +   + l++++ l +   r+le++l +le+
  EEA20886.1  97 EIQNKVCKSSINVLADIVKSVEDNAKRLEQGNPDRIGIEGEIAEVHSRLDAAQIDKKGLQSQIRLNKGSVRSLERRLNALET 178
                 5566777889*******************************************************************99886 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 1.3
        ADIP  75 kierlktqleqlerela.l 92 
                 +++ l++++e+ ere+  l
  EEA20886.1 180 RVDALEASVERVERENHeL 198
                 4555555555555554422 PP

  == domain 4  score: 6.2 bits;  conditional E-value: 0.0099
        ADIP  44 Llqardr.dleqreslnetirkleaeierlqskierlktqleqlerela.lvqakerqlekklktleqklknekeelqrlknalqqi 128
                 Llq++ r ++    sl+ +++ le++ e+ + + +r++   ++ e  ++ ++q+ +r++++++ +le +++ +++ l  ++++++ +
  EEA20886.1 271 LLQSQIRlNKGSMVSLAGRVKGLESSVEHHREEKNRVDSLESDMEDLIQvTLQRVKRENKARMDNLELQNQALQDALGQTQRIIEGL 357
                 6665544388888999*********************************9***************************9999998765 PP

>> NPV_P10  Nucleopolyhedrovirus P10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.1         1   1.1e+03      15      33 ..      36      54 ..      30      74 .. 0.53
   2 ?    8.7   1.8    0.0023       2.4      13      60 ..      72     119 ..      61     131 .. 0.78
   3 ?    5.2   0.1     0.028        30      12      61 ..     137     191 ..     132     216 .. 0.67
   4 ?    5.9   0.2     0.017        18      18      63 ..     229     267 ..     225     277 .. 0.85
   5 ?    2.1   1.0      0.26   2.8e+02      18      38 ..     305     326 ..     282     359 .. 0.50
   6 ?    2.0   0.0      0.27   2.8e+02       5      35 ..     364     387 ..     356     417 .. 0.52

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 1
     NPV_P10 15 avddkVdalqqqvddvqen 33
                +++++Vdal +++d +q +
  EEA20886.1 36 DLQSRVDALLEKMDLLQLQ 54
                4555555555555544333 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.0023
     NPV_P10  13 ikavddkVdalqqqvddvqenlpdvtelnekLdaqs.aqLaeletkven 60 
                  + vd kV  lq  v  +q+ ++d te+++k+ + s + La++ ++ve+
  EEA20886.1  72 LETVDRKVAQLQPDVFAMQDAFQD-TEIQNKVCKSSiNVLADIVKSVED 119
                 678*********************.889999755442566777766665 PP

  == domain 3  score: 5.2 bits;  conditional E-value: 0.028
     NPV_P10  12 dikavddkVdalqqqv....ddvqenlpdvtelnekLdaq.saqLaeletkvenI 61 
                 +i++v +++da q        +++ n   v  l+ +L+a+ ++ +++le++ve +
  EEA20886.1 137 EIAEVHSRLDAAQIDKkglqSQIRLNKGSVRSLERRLNALeTNRVDALEASVERV 191
                 6777777777766665222233444555677777777776345677777777665 PP

  == domain 4  score: 5.9 bits;  conditional E-value: 0.017
     NPV_P10  18 dkVdalqqqvddvqenlpdvtelnekLdaqsaqLaeletkvenIqd 63 
                 d+V+ l+++v++++++ +d      ++d+   ++ae+++kve+I+d
  EEA20886.1 229 DRVTCLEANVERLEQDAKD------RIDGGL-AVAEFQSKVEAIED 267
                 799*************999......788754.57899999999986 PP

  == domain 5  score: 2.1 bits;  conditional E-value: 0.26
     NPV_P10  18 dkVdalqqqvddv.qenlpdvt 38 
                 ++Vd+l++ ++d+ q  l+ v+
  EEA20886.1 305 NRVDSLESDMEDLiQVTLQRVK 326
                 3444444444332133344443 PP

  == domain 6  score: 2.0 bits;  conditional E-value: 0.27
     NPV_P10   5 iLlvIradikavddkVdalqqqvddvqenlp 35 
                  L +I +d + ++++V       + +++  +
  EEA20886.1 364 ALGQINTDLSGLKQRV-------EMLESSKR 387
                 3444444444444444.......44444433 PP

>> DUF4164  Domain of unknown function (DUF4164)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.2       1.6   1.6e+03       7      80 ..      31      45 ..      21      81 .. 0.61
   2 ?   -1.3   0.0       2.6   2.7e+03      15      45 ..      60      90 ..      45      92 .. 0.68
   3 ?    1.6   0.1      0.31   3.3e+02       6      52 ..     110     156 ..     105     164 .. 0.75
   4 ?    2.7   3.7      0.15   1.5e+02      23      66 ..     168     214 ..     166     232 .. 0.63
   5 ?   12.6   1.2   0.00012      0.13      11      54 ..     232     275 ..     221     281 .. 0.89
   6 ?    7.6   2.3    0.0042       4.5      13      51 ..     286     325 ..     279     357 .. 0.70
   7 ?    4.1   0.0     0.055        58       6      56 ..     361     412 ..     356     417 .. 0.84

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 1.6
     DUF4164  7 eaaltrLeaaldsLEkavdrrleaerkrdeleaeiealgedrsRLaeeLdqaearaarleevnrEvsrrLkaai 80
                e+ +++L+  +d+L                                                            
  EEA20886.1 31 EQSTSDLQSRVDAL-----------------------------------------------------------L 45
                33333333333332...........................................................2 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 2.6
     DUF4164 15 aaldsLEkavdrrleaerkrdeleaeiealg 45
                ++++sL+++++   + +rk ++l+ ++ a++
  EEA20886.1 60 GSIQSLTGRLEVLETVDRKVAQLQPDVFAMQ 90
                4788888888877777777777777776665 PP

  == domain 3  score: 1.6 bits;  conditional E-value: 0.31
     DUF4164   6 leaaltrLeaaldsLEkavdrrleaerkrdeleaeiealgedrsRLa 52 
                 l+++ +  e   ++LE+    r+  e++ +e+ +++ a + d++ L 
  EEA20886.1 110 LADIVKSVEDNAKRLEQGNPDRIGIEGEIAEVHSRLDAAQIDKKGLQ 156
                 56666667777788888888888888888888888888888887665 PP

  == domain 4  score: 2.7 bits;  conditional E-value: 0.15
     DUF4164  23 avdrrleaerkr..deleaeiealgedrsRL.aeeLdqaearaarle 66 
                 +++rrl+a +++  d+lea +e+++++   L + e d  +a ++ + 
  EEA20886.1 168 SLERRLNALETNrvDALEASVERVERENHELfEREYDRISAAESDVR 214
                 57788888877777888888888877665442445555555554444 PP

  == domain 5  score: 12.6 bits;  conditional E-value: 0.00012
     DUF4164  11 trLeaaldsLEkavdrrleaerkrdeleaeiealgedrsRLaee 54 
                 t Lea +++LE+  + r++   + +e+++++ea+++dr+ L  +
  EEA20886.1 232 TCLEANVERLEQDAKDRIDGGLAVAEFQSKVEAIEDDRKLLQSQ 275
                 5599***********************************99876 PP

  == domain 6  score: 7.6 bits;  conditional E-value: 0.0042
     DUF4164  13 LeaaldsLEkavdrrleaerkrdeleaei.ealgedrsRL 51 
                 L + ++ LE++v++++e+++  d+le+++  +++   +R 
  EEA20886.1 286 LAGRVKGLESSVEHHREEKNRVDSLESDMeDLIQVTLQRV 325
                 7788999********************9944445444444 PP

  == domain 7  score: 4.1 bits;  conditional E-value: 0.055
     DUF4164   6 leaaltrLeaaldsLEkavdrrleaerkrdeleaeiealgedrsR.LaeeLd 56 
                 ++ al ++++ l  L ++v++  +++r+ d++ +  + ++e r R L+++ d
  EEA20886.1 361 IQTALGQINTDLSGLKQRVEMLESSKRDGDSVYTITTSMQENRFRnLEARVD 412
                 68899**************998888888888888889999999875666666 PP

>> BLOC1_2  Biogenesis of lysosome-related organelles complex-1 subunit 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.3      0.32   3.4e+02      33      78 ..      38      83 ..      27      97 .. 0.60
   2 ?    2.8   0.1      0.14   1.5e+02      26      55 ..      97     126 ..      80     147 .. 0.72
   3 ?    6.7   1.1    0.0086       9.1       2      93 ..     101     193 ..     100     196 .. 0.87
   4 ?    4.9   0.9      0.03        32      34      74 ..     179     213 ..     152     250 .. 0.48
   5 ?    5.0   0.2     0.029        30      12      70 ..     259     317 ..     254     321 .. 0.82
   6 ?    1.8   0.6      0.28   2.9e+02      26      86 ..     323     384 ..     320     388 .. 0.61

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.32
     BLOC1_2 33 sekykklkdvaaslekkleklnekyeelqpylqqidqiekqvteLe 78
                ++++++l ++++ l+ ++   n   ++l   l+ ++ ++++v++L+
  EEA20886.1 38 QSRVDALLEKMDLLQLQIRLKNGSIQSLTGRLEVLETVDRKVAQLQ 83
                4455555555555555555555555566666666666666666665 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.14
     BLOC1_2  26 eklNeaasekykklkdvaaslekkleklne 55 
                 e  N++  + ++ l+d+++s+e+++++l++
  EEA20886.1  97 EIQNKVCKSSINVLADIVKSVEDNAKRLEQ 126
                 455666666666666666666666666665 PP

  == domain 3  score: 6.7 bits;  conditional E-value: 0.0086
     BLOC1_2   2 rmfekvskyleaeleatvedyklLeklNeaasekykklkdvaaslekkleklnekyeelqpylqqidqiekqvteLeea.vseLDeyskeLEa 93 
                 ++++++ ++l   ++++ ++ k Le+ N   +    ++++v + l +   + + ++ +++ ++ ++  +e++++ Le++ v++L++ + + E 
  EEA20886.1 101 KVCKSSINVLADIVKSVEDNAKRLEQGNPDRIGIEGEIAEVHSRLDAAQIDKKGLQSQIRLNKGSVRSLERRLNALETNrVDALEASVERVER 193
                 56777888888888888999999999999999999999999999999999999***********************97549999998888875 PP

  == domain 4  score: 4.9 bits;  conditional E-value: 0.03
     BLOC1_2  34 ekykklkdvaaslekkleklnekyeelqpylqqidqiekqv 74 
                 +++++l+ +++ +e++ ++l e         ++i + e +v
  EEA20886.1 179 NRVDALEASVERVERENHELFE------REYDRISAAESDV 213
                 4444444444444443333322......2223333333333 PP

  == domain 5  score: 5.0 bits;  conditional E-value: 0.029
     BLOC1_2  12 eaeleatvedyklLeklNeaasekykklkdvaaslekkleklnekyeelqpylqqidqi 70 
                 ++++ea  +d klL+   +       +l+ ++++le+++e+ +e+++ ++++ + ++++
  EEA20886.1 259 QSKVEAIEDDRKLLQSQIRLNKGSMVSLAGRVKGLESSVEHHREEKNRVDSLESDMEDL 317
                 67888899999999999999999999999999999999999999998888877666654 PP

  == domain 6  score: 1.8 bits;  conditional E-value: 0.28
     BLOC1_2  26 eklNeaasekykklkdvaaslekkleklnekyeelqpylq.qidqiekqvteLeeavseLDe 86 
                 +++ ++  ++ ++l+ + + l++ l ++++  e l+  +q  + qi+++++ L++ v++L++
  EEA20886.1 323 QRVKRENKARMDNLELQNQALQDALGQTQRIIEGLHIGIQtALGQINTDLSGLKQRVEMLES 384
                 55555555566666666666666666666666665554442577777777777777777765 PP

>> DUF4618  Domain of unknown function (DUF4618)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   8.2   6.7e-05     0.071      58     225 ..      23     190 ..      13     201 .. 0.76
   2 ?   -2.3   0.0       2.2   2.3e+03     208     225 ..     230     247 ..     221     251 .. 0.78
   3 ?    0.5   0.1       0.3   3.2e+02     178     221 ..     259     302 ..     243     308 .. 0.73
   4 ?    1.3   2.9      0.17   1.8e+02      69     201 ..     319     353 ..     283     392 .. 0.55

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 6.7e-05
     DUF4618  58 eksskkqleqakaeLqeweekeekklekLeqqleqlnakvqklqeelnvLstYkDkeYpvkavqIanlvrqlqqlkdsqqdeldeleelikevleklsk 156
                 ++ss++ leq++++Lq+  + + +k+  L+ q++  n  +q+l   l+vL+t  D+     +  +  ++   q+++ +++     ++ l+    ++ ++
  EEA20886.1  23 DESSEEGLEQSTSDLQSRVDALLEKMDLLQLQIRLKNGSIQSLTGRLEVLET-VDRKVAQLQPDVFAMQDAFQDTEIQNKVCKSSINVLADI-VKSVED 119
                 6789999*********************************************.566555555556666666666666555555555544433.334444 PP

     DUF4618 157 kiqkkkekllksl.aektlkatqeaLlqktlenqvlkkeiekfrefieeleeeipeLk.aeveqLqaqaee 225
                 ++++ ++   + +  e  +++ ++ L +  ++++ l+++i+ ++  +  le ++++L+ + v++L+a++e 
  EEA20886.1 120 NAKRLEQGNPDRIgIEGEIAEVHSRLDAAQIDKKGLQSQIRLNKGSVRSLERRLNALEtNRVDALEASVER 190
                 444433333333326778999************************************83579999998874 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 2.2
     DUF4618 208 eipeLkaeveqLqaqaee 225
                 ++  L+a+ve+L+++a++
  EEA20886.1 230 RVTCLEANVERLEQDAKD 247
                 577789999999998876 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.3
     DUF4618 178 qeaLlqktlenqvlkkeiekfrefieeleeeipeLkaeveqLqa 221
                 q+ +++   +++ l+++i+ ++  +  l  +++ L+++ve+ ++
  EEA20886.1 259 QSKVEAIEDDRKLLQSQIRLNKGSMVSLAGRVKGLESSVEHHRE 302
                 45555555667778888888888888888888888888876554 PP

  == domain 4  score: 1.3 bits;  conditional E-value: 0.17
     DUF4618  69 kaeLqeweekeekklekLeqqleqlnakvqklqeelnvLstYkDkeYpvkavqIanlvrqlqqlkdsqqdeldeleelikevleklskkiqkkkekllk 167
                 +  Lq ++ + + ++ +Le q ++l++                                                                        
  EEA20886.1 319 QVTLQRVKRENKARMDNLELQNQALQDA----------------------------------------------------------------------- 346
                 2233333333333333333333333333....................................................................... PP

     DUF4618 168 slaektlkatqeaLlqktlenqvlkkeiekfref 201
                                            + + +++
  EEA20886.1 347 ---------------------------LGQTQRI 353
                 ...........................3333333 PP

>> Methyltransf_32  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.1      0.95     1e+03      64      64 ..     188     188 ..      89     272 .. 0.65
   2 ?    8.9   1.0    0.0013       1.4      49     124 ..     285     358 ..     272     360 .. 0.81

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.95
  Methyltransf_32  64 v 64 
                      v
       EEA20886.1 188 V 188
                      1 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.0013
  Methyltransf_32  49 eyklkvvgidakeelvekaekraeklgkkfnkrlsfaelsieeatssktltkkveaeeekeeqeekesvdvligLH 124
                       +  +v g++++ e+ ++ ++r + l++++++ ++ + + ++ +++ k + +++e ++++ +++  +++ ++ gLH
       EEA20886.1 285 SLAGRVKGLESSVEHHREEKNRVDSLESDMEDLIQVTLQRVK-REN-KARMDNLELQNQALQDALGQTQRIIEGLH 358
                      46789*************************655555555555.543.4567789999999999************* PP

>> Exonuc_VII_L  Exonuclease VII, large subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   4.1      0.14   1.5e+02     151     259 ..      52     176 ..      12     181 .. 0.29
   2 ?    8.5   3.9    0.0013       1.3     161     273 ..     156     286 ..     128     303 .. 0.49
   3 ?    6.5   4.1     0.005       5.3     140     259 ..     298     414 ..     285     419 .. 0.54

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.14
  Exonuc_VII_L 151 elerrlekaikrll.......eekkqrleklasrlkspeellerk..rqrldeleerleralkkqlkkkrerleelk.erlk....ekleekkerlk 233
                   +l+ rl++   + l       e+  +++ +l+ ++   ++ +++   ++++ + + ++ + + k+++ +++rle+ + +  +     +++e ++rl+
    EEA20886.1  52 QLQIRLKNGSIQSLtgrlevlETVDRKVAQLQPDVFAMQDAFQDTeiQNKVCKSSINVLADIVKSVEDNAKRLEQGNpD--RigieGEIAEVHSRLD 146
                   1111111111111111111111111111111111111111111110111111111111111222222222222222211..0222333333333332 PP

  Exonuc_VII_L 234 klkerle....lleekkerleeleekleal 259
                   + +   +    +++ +k ++++le++l+al
    EEA20886.1 147 AAQIDKKglqsQIRLNKGSVRSLERRLNAL 176
                   222222233344555555555666666665 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0013
  Exonuc_VII_L 161 krlleekkqrleklasrl..................k.speellerkrqrldeleerleralkkqlkkkrerleelkerlkekleekkerlkklker 238
                   +++++ +k  +++l++rl                  + +++el+er+ +r++ +e+++++  + ++++ ++++++++          ++++++l++ 
    EEA20886.1 156 QSQIRLNKGSVRSLERRLnaletnrvdaleasvervErENHELFEREYDRISAAESDVRALGEATYDRYSQAIDRVT--------CLEANVERLEQD 244
                   33333333334444433311110000000000011121333444444444444444444433333444444444443........333333333333 PP

  Exonuc_VII_L 239 le.......lleekkerleeleeklealsplkvLkrGyaivr 273
                    +        ++e ++++e++e+  ++l+ +  L++G  +  
    EEA20886.1 245 AKdridgglAVAEFQSKVEAIEDDRKLLQSQIRLNKGSMVSL 286
                   334445777799999999999999999999999999976655 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.005
  Exonuc_VII_L 140 pdkaeleeqleelerrlekaikrlleekkqrleklasrlkspeellerkrqrldeleerleralkkqlkkkrerleelkerlk..ekleekkerlkk 234
                   ++++e ++++++le+ +e+ i+ +l++ k++ ++   +l+ +++ l+++  + +++ e l+  ++++l + +++l+ lk+r++  e+ +        
    EEA20886.1 298 EHHREEKNRVDSLESDMEDLIQVTLQRVKRENKARMDNLELQNQALQDALGQTQRIIEGLHIGIQTALGQINTDLSGLKQRVEmlESSK-------- 386
                   44455566666666666666666665555554444445554455555555555555555555555566666666666665553222222........ PP

  Exonuc_VII_L 235 lkerle........lleekkerleeleekleal 259
                        +        +++ +++r+++le++++ l
    EEA20886.1 387 -----RdgdsvytiTTSMQENRFRNLEARVDGL 414
                   .....1233333334666677777777777665 PP

>> ATG16  Autophagy protein 16 (ATG16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   2.2     0.017        18      93     138 ..      30      75 ..      18      83 .. 0.88
   2 ?    3.3   0.1     0.079        83      90     144 ..      72     126 ..      71     131 .. 0.91
   3 ?    2.2   7.6      0.17   1.8e+02     124     187 ..     137     201 ..     110     209 .. 0.51
   4 ?    3.9  14.5     0.052        54      17     174 ..     217     386 ..     203     414 .. 0.57

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.017
       ATG16  93 lyksrgelaqrllelneelqkleeklkedeerlaeleaeraaletk 138
                 l +s ++l++r+ +l e+++ l+ +++ ++ ++++l+ + ++let 
  EEA20886.1  30 LEQSTSDLQSRVDALLEKMDLLQLQIRLKNGSIQSLTGRLEVLETV 75 
                 6778999*********************************999975 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.079
       ATG16  90 laelyksrgelaqrllelneelqkleeklkedeerlaeleaeraaletklkdree 144
                 l+++ ++ ++l+  + +++++ q+ e + k  +++++ l + ++++e++ k++e+
  EEA20886.1  72 LETVDRKVAQLQPDVFAMQDAFQDTEIQNKVCKSSINVLADIVKSVEDNAKRLEQ 126
                 567889999************************************9999999886 PP

  == domain 3  score: 2.2 bits;  conditional E-value: 0.17
       ATG16 124 rlaeleaeraaletklkdreeelrekeklvqdlqDElsaLql.qlnqaEeklrklekENkeLveR 187
                 ++ae++++  a +   k ++ ++r  +  v  l   l+aL+  ++  +E+  +++e+EN eL eR
  EEA20886.1 137 EIAEVHSRLDAAQIDKKGLQSQIRLNKGSVRSLERRLNALETnRVDALEASVERVERENHELFER 201
                 33333333333333333333344444444444444444443314556666666666666666665 PP

  == domain 4  score: 3.9 bits;  conditional E-value: 0.052
       ATG16  17 faeliqaynrLldrtsaleaenaklekaaasaks.........sksskksakekeasasq...........snskqsakiqsleqklaqlreelaelyk 95 
                  ++ ++ y++ +dr+  lea  ++le+ a+++           sk+++  + +      +           s       + sl+ +++ l + ++    
  EEA20886.1 217 GEATYDRYSQAIDRVTCLEANVERLEQDAKDRIDgglavaefqSKVEAIEDDR------KllqsqirlnkgS-------MVSLAGRVKGLESSVEHHRE 302
                 56788999999**********99998888888778876654443333333333......1344433555553.......33444444443333333333 PP

       ATG16  96 srgelaqrllelneelq.kleeklkedeerlaeleaeraaletklkdreeelrekeklvq....dlqDElsaLqlqlnqaEekl 174
                 +++   +   ++++ +q +l++  +e+++r+++le +++al+++l + +  ++++   +q    ++  +ls L+ +++++E+ +
  EEA20886.1 303 EKNRVDSLESDMEDLIQvTLQRVKRENKARMDNLELQNQALQDALGQTQRIIEGLHIGIQtalgQINTDLSGLKQRVEMLESSK 386
                 333333333333333331355556666677777777777777777777777777766666555544555555555555555444 PP

>> FlaC_arch  Flagella accessory protein C (FlaC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       3.5   3.7e+03      19      33 ..      30      44 ..      24      53 .. 0.52
   2 ?   -1.3   0.1       2.9     3e+03      16      23 ..      72      79 ..      40     100 .. 0.55
   3 ?   -0.6   0.1       1.7   1.8e+03      13      39 ..      97     123 ..      78     125 .. 0.62
   4 ?   -1.6   0.0       3.4   3.6e+03       5      31 ..     134     160 ..     133     169 .. 0.77
   5 ?    6.5   0.3      0.01        11       4      33 ..     168     198 ..     165     204 .. 0.72
   6 ?   -1.9   0.0       4.3   4.5e+03       5      35 ..     234     243 ..     227     250 .. 0.57
   7 ?   -1.4   0.1         3   3.1e+03       1      33 [.     261     293 ..     254     301 .. 0.51
   8 ?    8.7   0.8    0.0021       2.2       1      38 [.     306     344 ..     306     349 .. 0.82
   9 ?    4.2   0.0     0.054        57      13      54 ..     362     404 ..     359     405 .. 0.71

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 3.5
   FlaC_arch 19 vkkeneelsksveel 33
                ++++ ++l++ v+ l
  EEA20886.1 30 LEQSTSDLQSRVDAL 44
                344444444444444 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 2.9
   FlaC_arch 16 letvkken 23
                letv ++ 
  EEA20886.1 72 LETVDRKV 79
                33444444 PP

  == domain 3  score: -0.6 bits;  conditional E-value: 1.7
   FlaC_arch  13 steletvkkeneelsksveelkenVkd 39 
                 +++ +  k++++ l + v+ +++n k+
  EEA20886.1  97 EIQNKVCKSSINVLADIVKSVEDNAKR 123
                 444444555566666666666666555 PP

  == domain 4  score: -1.6 bits;  conditional E-value: 3.4
   FlaC_arch   5 lEnklsklsteletvkkeneelsksve 31 
                 +E ++ ++ ++l+ ++ + + l++++ 
  EEA20886.1 134 IEGEIAEVHSRLDAAQIDKKGLQSQIR 160
                 788999999999999988888887775 PP

  == domain 5  score: 6.5 bits;  conditional E-value: 0.01
   FlaC_arch   4 elEnklsklst.eletvkkeneelsksveel 33 
                 +lE +l+ l+t +++ ++++ e ++ + +el
  EEA20886.1 168 SLERRLNALETnRVDALEASVERVERENHEL 198
                 6788888888877777777777777776665 PP

  == domain 6  score: -1.9 bits;  conditional E-value: 4.3
   FlaC_arch   5 lEnklsklsteletvkkeneelsksveelke 35 
                 lE  +++l                     ++
  EEA20886.1 234 LEANVERL---------------------EQ 243
                 44444444.....................44 PP

  == domain 7  score: -1.4 bits;  conditional E-value: 3
   FlaC_arch   1 ridelEnklsklsteletvkkeneelsksveel 33 
                 +++ +E + + l++++   k ++ +l   v+ l
  EEA20886.1 261 KVEAIEDDRKLLQSQIRLNKGSMVSLAGRVKGL 293
                 344444444444444444444444444444444 PP

  == domain 8  score: 8.7 bits;  conditional E-value: 0.0021
   FlaC_arch   1 ridelEnklskl.steletvkkeneelsksveelkenVk 38 
                 r+d+lE+++++l +++l+ vk+en+   +++e  ++  +
  EEA20886.1 306 RVDSLESDMEDLiQVTLQRVKRENKARMDNLELQNQALQ 344
                 8*********97366*********998888887666665 PP

  == domain 9  score: 4.2 bits;  conditional E-value: 0.054
   FlaC_arch  13 steletvkkeneelsksveelkenVkdllsLYEvVsn.qvNPF 54 
                 +t l+ + ++++ l++ ve+l+ + +d  s+Y + +  q N F
  EEA20886.1 362 QTALGQINTDLSGLKQRVEMLESSKRDGDSVYTITTSmQENRF 404
                 5678888888899999999998877776666666665566655 PP

>> Syntaxin-6_N  Syntaxin 6, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   1.9      0.39   4.2e+02      30      65 ..      21      56 ..       2     118 .. 0.65
   2 ?   -0.1   0.1       1.3   1.4e+03      51      69 ..     104     119 ..      60     144 .. 0.52
   3 ?    2.1   2.6      0.27   2.8e+02      43      78 ..     166     203 ..      91     220 .. 0.54
   4 ?    6.0   4.3     0.017        18      34      84 ..     285     341 ..     225     356 .. 0.74
   5 ?    7.2   0.0    0.0068       7.2      46      73 ..     361     388 ..     349     414 .. 0.80

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.39
  Syntaxin-6_N 30 dtssstseeldetrteLrkalrsiewdledLeetvr 65
                  + ++s++e l++ +++L++ ++ + ++++ L+  +r
    EEA20886.1 21 SDDESSEEGLEQSTSDLQSRVDALLEKMDLLQLQIR 56
                  223356888888888888888888888888877773 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 1.3
  Syntaxin-6_N  51 rsiewdledLeetvrivek 69 
                   +s    ++ L + v+ ve 
    EEA20886.1 104 KSS---INVLADIVKSVED 119
                   222...2222222222233 PP

  == domain 3  score: 2.1 bits;  conditional E-value: 0.27
  Syntaxin-6_N  43 rteLrkalrsiew.dledLeetvriveknpsk.fkide 78 
                    + L++ l+ +e+  ++ Le +v+ ve+++++ f+ + 
    EEA20886.1 166 VRSLERRLNALETnRVDALEASVERVERENHElFEREY 203
                   33444444444431344555555555554444444444 PP

  == domain 4  score: 6.0 bits;  conditional E-value: 0.017
  Syntaxin-6_N  34 s......tseeldetrteLrkalrsiewdledLeetvriveknpskfkidekelsrr 84 
                   s        e++ e+++e ++ ++s+e d+edL ++     k ++k ++d+ el+++
    EEA20886.1 285 SlagrvkGLESSVEHHREEKNRVDSLESDMEDLIQVTLQRVKRENKARMDNLELQNQ 341
                   1445555778889999999**************998844444457777777777765 PP

  == domain 5  score: 7.2 bits;  conditional E-value: 0.0068
  Syntaxin-6_N  46 LrkalrsiewdledLeetvriveknpsk 73 
                   +++al++i++dl+ L++ v+++e+++++
    EEA20886.1 361 IQTALGQINTDLSGLKQRVEMLESSKRD 388
                   789********************98754 PP

>> CK2S  Casein Kinase 2 substrate
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.4      0.47     5e+02      71     101 ..      61      91 ..      23     126 .. 0.70
   2 ?   -2.1   0.1       2.9   3.1e+03      66     101 ..     167     200 ..     150     219 .. 0.55
   3 ?   12.4   2.3    0.0001      0.11       6     101 ..     297     394 ..     292     410 .. 0.87

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.47
        CK2S  71 vlakLrekleelqkvrdsleklvrdalqlye 101
                  +++L   le l+ v +++++l+ d++ + +
  EEA20886.1  61 SIQSLTGRLEVLETVDRKVAQLQPDVFAMQD 91 
                 4666777777777777777777766665544 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 2.9
        CK2S  66 ealeevlakLrekleelqkvrdsleklvrdalqlye 101
                  +le+ l  L+   ++++ +  s+e+  r+  +l e
  EEA20886.1 167 RSLERRLNALET--NRVDALEASVERVERENHELFE 200
                 444444444432..3444444444444444444444 PP

  == domain 3  score: 12.4 bits;  conditional E-value: 0.0001
        CK2S   6 frkveeqrekWkellseseslleslsnlaeqlqa..lqnvklygtplrdfpdlqerLrekqlealeevlakLrekleelqkvrdsleklvrdalqlye 101
                  +  +e++++ ++l+s++e l+++    +++ +   + n +l++  l+d  ++ +r++e +  ++++ l +++ +l+ l++ ++ le+ +rd+ ++y 
  EEA20886.1 297 VEHHREEKNRVDSLESDMEDLIQVTLQRVKRENKarMDNLELQNQALQDALGQTQRIIEGLHIGIQTALGQINTDLSGLKQRVEMLESSKRDGDSVYT 394
                 5667899**********************99764127788889999*****************************************99998877665 PP

>> DUF641  Plant protein of unknown function (DUF641)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.2     0.015        16      70     124 ..      24      78 ..       5      83 .. 0.84
   2 ?    8.4   0.3    0.0024       2.5      70     121 ..     128     179 ..      86     201 .. 0.85
   3 ?    1.1   0.4      0.45   4.7e+02      81     120 ..     256     295 ..     221     317 .. 0.66
   4 ?   -0.7   1.7       1.6   1.7e+03      89     121 ..     317     349 ..     291     387 .. 0.64

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.015
      DUF641  70 eaeeseleaeiqeqrsllktyeitvkkleaelkakdseieeLkekLeeaeksnkk 124
                 e +e+ le+   +++s ++++   ++ l+ +++ k+  i++L  +Le +e   +k
  EEA20886.1  24 ESSEEGLEQSTSDLQSRVDALLEKMDLLQLQIRLKNGSIQSLTGRLEVLETVDRK 78 
                 2578889999999*********************************988877665 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0024
      DUF641  70 eaeeseleaeiqeqrsllktyeitvkkleaelkakdseieeLkekLeeaeks 121
                 ++++  +e ei e +s l++ +i  k l+++++  +  + +L+++L+++e +
  EEA20886.1 128 NPDRIGIEGEIAEVHSRLDAAQIDKKGLQSQIRLNKGSVRSLERRLNALETN 179
                 37788899999********************************999988765 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.45
      DUF641  81 qeqrsllktyeitvkkleaelkakdseieeLkekLeeaek 120
                  e +s++++ e   k l+++++  +  + +L  +++ +e+
  EEA20886.1 256 AEFQSKVEAIEDDRKLLQSQIRLNKGSMVSLAGRVKGLES 295
                 4566666666666666666666666666665555444433 PP

  == domain 4  score: -0.7 bits;  conditional E-value: 1.6
      DUF641  89 tyeitvkkleaelkakdseieeLkekLeeaeks 121
                   ++t++++++e ka+  ++e  ++ L++a  +
  EEA20886.1 317 LIQVTLQRVKRENKARMDNLELQNQALQDALGQ 349
                 345555555555555555555555555555444 PP

>> DUF4988  Domain of unknown function
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.3     0.029        31       1      30 [.      37      66 ..      30      81 .. 0.77
   2 ?    2.2   0.1      0.12   1.3e+02       1      24 [.     169     193 ..     163     211 .. 0.74
   3 ?    2.5   0.1     0.098     1e+02      10      63 ..     229     287 ..     221     297 .. 0.66
   4 ?   -0.7   0.0      0.95     1e+03       9      20 ..     304     315 ..     280     339 .. 0.59
   5 ?    1.3   0.0      0.22   2.3e+02       2      32 ..     369     398 ..     360     418 .. 0.67

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.029
     DUF4988  1 leddvndlkdrvaaleeqvkelndniealk 30
                l+++v++l +++  l+ q++  n +i++l 
  EEA20886.1 37 LQSRVDALLEKMDLLQLQIRLKNGSIQSLT 66
                577888888888888888888888888875 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.12
     DUF4988   1 leddvndlk.drvaaleeqvkelnd 24 
                 le ++n+l+ +rv ale+ v+ ++ 
  EEA20886.1 169 LERRLNALEtNRVDALEASVERVER 193
                 4566777754677788777777765 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.098
     DUF4988  10 drvaaleeqvkelndnie.alkklleegkviteveensdg....syvltlsdgktitlt 63 
                 drv+ le++v+ l+++ +  +   l   ++ ++ve  +d     + ++ l+ g+ ++l+
  EEA20886.1 229 DRVTCLEANVERLEQDAKdRIDGGLAVAEFQSKVEAIEDDrkllQSQIRLNKGSMVSLA 287
                 89999999999998877514544334555555555555556666777777777777765 PP

  == domain 4  score: -0.7 bits;  conditional E-value: 0.95
     DUF4988   9 kdrvaaleeqvk 20 
                 k+rv +le+ ++
  EEA20886.1 304 KNRVDSLESDME 315
                 334444444433 PP

  == domain 5  score: 1.3 bits;  conditional E-value: 0.22
     DUF4988   2 eddvndlkdrvaaleeqvkelndniealkkl 32 
                 + d++ lk+rv+ le+  ++  d++ ++ + 
  EEA20886.1 369 NTDLSGLKQRVEMLESSKRD-GDSVYTITTS 398
                 45677788888888876544.3444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (447 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1199  (0.0668749); expected 358.6 (0.02)
Passed bias filter:                      476  (0.0265492); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                        32  (0.00178482); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              17  [number of targets reported over threshold]
# CPU time: 0.96u 0.33s 00:00:01.29 Elapsed: 00:00:00.48
# Mc/sec: 2781.67
//
Query:       EEA20887.1  [L=564]
Description: general amino acid permease (Agp2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   2.2e-103  346.5  42.4   2.6e-103  346.2  42.4    1.0  1  AA_permease    Amino acid permease
    3.6e-21   75.5  43.7    5.2e-21   75.0  43.7    1.2  1  AA_permease_2  Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  346.2  42.4  2.9e-107  2.6e-103       2     473 ..      57     522 ..      56     525 .. 0.97

  Alignments for each domain:
  == domain 1  score: 346.2 bits;  conditional E-value: 2.9e-107
  AA_permease   2 vlvialggviGtglfvglgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgpelGfviGlnylfswitvlaleltaasi 99 
                  v+++a+gg+iGt l+v +++ l ++Gp+g+++a+l++g+v+++v  +++e++t++p+ + f  + ++ ++++lGf++++n++++ ++ +++e++a++i
   EEA20887.1  57 VQLFAIGGAIGTSLYVQIASSLPKGGPAGLFIAFLIWGLVMWAVNECFAEMVTYMPVPSPFIRFGTEWVDDALGFAMAWNFFLNMAFLVPFEIVAMNI 154
                  89************************************************************************************************ PP

  AA_permease 100 liqfwelvtdlpkawvtgavflvvlliinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkga.gfrflgdngsifknnlppgfakeeeg 196
                  +i+fw  ++++p  +++++ ++v++ ++n+v+v+++g aef l+++k+i +i+++ +++i++ gg+p +++ gfr++ ++g+ f ++++ g    ++g
   EEA20887.1 155 MITFW--TDKVP-VEAIIVAMIVIYALLNVVSVRYFGVAEFYLSIFKVILMIGLFCFTFITMLGGNPIHDRyGFRYWDKPGA-FVEHFSTG----NTG 244
                  *****..*****.999999***************************************************************.55555555....599 PP

  AA_permease 197 afknfisvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasa..........aspfvifikesg 284
                  +f++++s++ +++f++tG e++ ++a+E+++P+k +P a++++v+ri++f+v+s+l++g+++p+nd +ll  ++ +          asp+vi+++ + 
   EEA20887.1 245 RFLGILSCMYQASFSITGPEYISMVAAETENPRKVLPPAFRSFVWRILVFFVGSSLCMGIVIPYNDSTLLG-IL-GgtvsgsgtgaASPYVIAMQRLQ 340
                  ******************************************************************98887.33.236777***************** PP

  AA_permease 285 vsvlaplinaviltaalssansslysasRvlyslakdglaPkvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwll 382
                  + vl++++na+i t+++s++n++l++a+R+l+ ++ +g+aPkvl++++k+gvP+ a+++s+++ lla+l  ++++a  +v+++l+ +++  ++i++++
   EEA20887.1 341 IHVLPHIVNALIMTSIFSAGNGLLFTATRTLHGMSISGHAPKVLSYCTKKGVPIWALAISILFCLLAFLQVNSSSA--EVMTYLVDLVTCCQMINYGF 436
                  ****************************************************************************..******************** PP

  AA_permease 383 iilsylrfRkalkyqgrsieelgfkaallplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfliilvgvklhvknk 473
                  ++++y  f  +lk+qg+s + l +k +++p++++l++   +++ll+ ++  +lt     + w+   f++ y ++  f+i++vg+kl++++k
   EEA20887.1 437 TAFTYRHFYSSLKKQGISRDTLAYKGRFQPYTSYLAMGGTLFMLLAGGYDVFLT-----GRWSIMWFFLDYGMIGFFIILFVGWKLIFRTK 522
                  ******************************************************.....9****************************987 PP

>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.0  43.7   5.8e-25   5.2e-21       8     401 ..      59     482 ..      55     515 .. 0.77

  Alignments for each domain:
  == domain 1  score: 75.0 bits;  conditional E-value: 5.8e-25
  AA_permease_2   8 alvigsvigsgifvknlaas....ggpalilwvwiavligslavllvyaElssalprsgGiyvytkaafgkkvaflsawfnwfayvpvlasilsva 99 
                    +++ig +ig+  +v+  +as    ggpa +++ +++ +++++av  ++aE+ + +p     + ++ +     ++f +aw ++   +++l+   +va
     EEA20887.1  59 LFAIGGAIGTSLYVQ--IASslpkGGPAGLFIAFLIWGLVMWAVNECFAEMVTYMPVPSPFIRFGTEWVDDALGFAMAWNFF-LNMAFLVPFEIVA 151
                    578999999999998..4444555***************************655***************9999999988665.5555576778999 PP

  AA_permease_2 100 asyllnalgpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfssl.....stetdtffpngwpgv 190
                    ++ +++++       ++++  i++a +++ al+n+++++  + + ++l i+k++l++ ++  + + +++g+  ++      +++ + f+ ++++g+
     EEA20887.1 152 MNIMITFWTD-----KVPVEAIIVAMIVIYALLNVVSVRYFGVAEFYLSIFKVILMIGLFCFTFITMLGGNPIHDRygfryWDKPGAFVEHFSTGN 242
                    9999999964.....45788999******************************6555555555555555555555589887666666888877764 PP

  AA_permease_2 191 .......llgllivlwsfdGfesaanvseevkk..kdvpkaifigllivlvlyllvniaflgvvpddei.......anlsnlgsv........... 259
                           l+ ++++ +s++G e+++ v+ e ++  k +p a  + +  +lv++++ ++ + +v+p +                 +           
     EEA20887.1 243 tgrflgiLSCMYQASFSITGPEYISMVAAETENprKVLPPAFRSFVWRILVFFVGSSLCMGIVIPYNDStllgilgG-------Tvsgsgtgaasp 331
                    4554444666677*****************6655388*****88888888888887777777777766634444441.......333333334344 PP

  AA_permease_2 260 aalffeavggkvvaiivvilialsllgaintavigssrvlealardgvlPrffakvnkfgspiraiiltaivslillllfllassaaynfllsvss 355
                    + + +++++  v+ +iv++li+ s++ a+n+++++++r+l+ ++  g  P++++   k+g pi a+ ++ +++l+ +l +  +s++ +++l+++ +
     EEA20887.1 332 YVIAMQRLQIHVLPHIVNALIMTSIFSAGNGLLFTATRTLHGMSISGHAPKVLSYCTKKGVPIWALAISILFCLLAFLQVNSSSAEVMTYLVDLVT 427
                    99999999999**************************************************************88777666666************ PP

  AA_permease_2 356 lgliisyllliigalilrkkrphl..kr..........pgkilvaiigalfllfllva 401
                    ++ +i y+++++++   +   +++   r          p+   ++ +++ ++lf+l a
     EEA20887.1 428 CCQMINYGFTAFTYRHFYSSLKKQgiSRdtlaykgrfqPY---TSYLAMGGTLFMLLA 482
                    **********988876666655554433556553334444...444445555555443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (564 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       750  (0.0418317); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.34s 00:00:00.99 Elapsed: 00:00:00.53
# Mc/sec: 3205.57
//
Query:       EEA20888.1  [L=288]
Description: aldolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      6e-47  160.0   0.3    8.1e-47  159.6   0.3    1.2  1  Aldolase_II  Class II Aldolase and Adducin N-terminal domain


Domain annotation for each model (and alignments):
>> Aldolase_II  Class II Aldolase and Adducin N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  159.6   0.3   4.5e-51   8.1e-47       2     186 .]      56     237 ..      55     237 .. 0.90

  Alignments for each domain:
  == domain 1  score: 159.6 bits;  conditional E-value: 4.5e-51
                  HHHHHHHHHHHTTSSCTTBCEEEEEET.STTEEEEEBTSS-GGGHTGGGEEEEETTSCEEEECECSSSTB-.TTHHHHHHHHHH-TT-SEEEEE--HH CS
  Aldolase_II   2 elaeasrllarrglvegtgGniSvrvp.eedsflitpsgvdfeeltaedlvvvdldsgevvegkekggkps.setplHlaiykarpdaravvHtHspa 97 
                  ++a a+r +ar+g++eg++G+iSvr+p  ed+f+i+p  v+f+ l+a+d++ v+ld gev+ g + +g+++ +++++H+a++k r+d++a++HtHs +
   EEA20888.1  56 HMAGAFRVFAREGYAEGISGHISVRDPeFEDRFWINPLAVHFGMLKASDMICVNLD-GEVIGG-NTEGSINaAGFQIHSAVHKSRKDVHAICHTHSVH 151
                  7999*********************999889************************9.****66.77888999************************** PP

                  HHHHHTCCSTSCHCCSSHHHHC.HSSSEEEEES-SSTTCHHH.HHHHHHHHHHS-SEEEETTTEEEEEESSHHHHHHHHHHHHHHHHHHH CS
  Aldolase_II  98 avalsalagkeglppltqeaaklllgdevpvipyaapgteel.gealaealkedakavllrnHGlltvGetleeAvalaetleeaaeiql 186
                  + a+sa+   ++l++++q+ + ++ + +  + +y  + +e   ge++a+ l+ + ka +l nHGlltvG+t++eA++l+  +e+++++ql
   EEA20888.1 152 GRAWSAF--ARPLEMINQDVCYFY-KAHSVYSDYGGIANESSeGEKIAKSLG-TGKASILMNHGLLTVGQTVDEAAFLFCLMERSCKVQL 237
                  *****88..799*********977.3434444555555444469*******8.668********************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (288 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       329  (0.0183502); expected 358.6 (0.02)
Passed bias filter:                      287  (0.0160076); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 1942.16
//
Query:       EEA20889.1  [L=525]
Description: benzoate 4-monooxygenase cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-56  192.5   0.0    4.9e-56  190.4   0.0    1.7  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  190.4   0.0   2.7e-60   4.9e-56      20     436 ..      51     483 ..      32     496 .. 0.78

  Alignments for each domain:
  == domain 1  score: 190.4 bits;  conditional E-value: 2.7e-60
                 CCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTST..TTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHHHHHHHHHTSHSTTTHHH CS
        p450  20 eelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkg..eefsgrpdeallatsrkpfkgkgvlfangekwkklRrfltptltsfgklslee 116
                 + + + +++l++kyg  +r+ + + ++  ls   a + ++++++  e +s++ +++ ++ +++ f   gv  ++  k+   +  +  +++s+     ++
  EEA20889.1  51 GARTRSIHYLHQKYGTAVRISPKEVSFSSLS---ALRTIYGAGSgfERTSFY-RMFDVYGRQNLFTFAGVKQHADRKKLLAHAYSKSAILSP-TAIAKP 144
                 55667799************99998888888...666677666300233332.555555555555555555555555555555555555555.446799 PP

                 HHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSH.....................HHHHHHHHHHHHHHHHCHHHHCCCC CS
        p450 117 lveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledek.....................lselvkaveelssllskssvqllll 194
                 l+e+ ++  +e l+ ++g     +i++ l  + ld+i+  l+g + +  +++                      ls +   ++++ ++l ++     l+
  EEA20889.1 145 LIEKNVKSYLELLEHEKGVT--EEIFQSLHWFSLDSITGFLYGDQHG--GTHAlkgdsgdrallgdiidpsrrlLSWYTVHMKNYTKWLYTR---TGLM 236
                 9****************999..7*********************977..2332578899****99999887776444455555555555333...3333 PP

                 CH.HHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHC.SCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        p450 195 fp.llkylptkllrklkeavkklkdlldklieerretldsa.kksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLak 291
                  + +    + ++++ +      +  ++ k  +  ++++ ++   ++++ +  l   +  +kg+  l+  ++a ++ + ++aG+dTts tl++++  L +
  EEA20889.1 237 EKvVTNLGLLPMKKPAT--YTGIRAHALKAWNSFEASVTENpPTRDMSIMEKLWRHSISEKGP-RLDGLDIASEAADHFLAGIDTTSDTLMFTIWALSR 332
                 33222222333444443..34566666666666666666665345777777777776444566.8********************************96 PP

                 ..SHHHHHHHHHHHHHHC.CTTT....T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEETTEEE-TT-EEEEEHHHHHT-TTTSSSTTS- CS
        p450 292 ..nPevqeklreEidevl.gdkr....eptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirgylipkGtevivnlyalhrdpevfpnPeeF 383
                   n ++qekl +E+d++   d      +p+ +   klpylda+ikEtLRl+ ++p + pR  + d++i+gylip+Gt+v++++y lhr+pevfp+P +F
  EEA20889.1 333 peNRKYQEKLIQEVDSIPdTD-CnadgNPSAEVADKLPYLDAIIKETLRLYAPLPASEPRSSLVDTKIDGYLIPAGTVVSMSPYNLHRNPEVFPEPLKF 430
                 5599************98444.34888************************************************************************ PP

                 -GGGGB-TTSCTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEE CS
        p450 384 dpeRFldekgnskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFeve 436
                 +peR+  e+g+    +  f +F+ G R+CiG +lA+ e+  +la + ++++ +
  EEA20889.1 431 NPERWHGENGDCTEMKKWFWAFSSGGRMCIGLHLAMAEMTTLLAAIYRRYTTS 483
                 **********88899*********************************99865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (525 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       385  (0.0214736); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3556.59
//
Query:       EEA20890.1  [L=620]
Description: calcium/calmodulin-dependent protein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      2e-72  243.7   0.0    3.5e-72  242.9   0.0    1.4  1  Pkinase      Protein kinase domain
      9e-37  126.7   0.0    2.7e-36  125.2   0.0    1.7  1  Pkinase_Tyr  Protein tyrosine kinase
     0.0012   18.2   1.0       0.89    8.8   0.0    3.0  3  Kinase-like  Kinase-like
  ------ inclusion threshold ------
      0.046   13.6   0.8        1.8    8.5   0.0    2.8  3  APH          Phosphotransferase enzyme family
       0.06   13.8   0.3       0.36   11.3   0.3    2.2  1  Spa1_C       Lantibiotic immunity protein Spa1 C-terminal dom


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  242.9   0.0   9.7e-76   3.5e-72       2     264 .]     104     391 ..     103     391 .. 0.92

  Alignments for each domain:
  == domain 1  score: 242.9 bits;  conditional E-value: 9.7e-76
                 EEEEEEEEESSEEEEEEEETTTT.EEEEEEEEECHCHCHHHHHHHHHHHHHHHHHSCTTB--EEEEEEESSEEEEEEE--TTEBHHHHHHHHSS--HHH CS
     Pkinase   2 ekleklGeGsfGkVykaveketg.kivAvKkikkekakkkkekkvlrEikilkklkhpnivrlyevfeekdelylvleyveggeladllerkgslseee 99 
                   ++k+G G+f++Vy+a+++ ++ ++vA+K+++k +++ +++ ++l+E++i+++l+hpniv+l+++ e+++ +y+vle+++ggel++ + r + +see 
  EEA20890.1 104 ILIQKMGDGAFSNVYRAKDTLSQmEEVAIKVVRKFEMNRNQRANILKEVQIMRQLDHPNIVKLVDFSESSQFYYIVLELCPGGELFHQIVRLTYFSEEL 202
                 5689**************98654289****************************************************************9999***** PP

                 HHHHHHHHHHHHHHHH.HTTEE-SS-SGGGEEEET.................................TTEEEE-SGTTSEESSSSCSBCTTTSCGGGS CS
     Pkinase 100 akkiakqilegleylH.skgiiHrDlKpeNiLide.................................kgelKitDFGlakelessskltsfvgtseYl 164
                  +++++q++e++eylH   g++HrD+KpeN+L+                                    g++Ki+DFGl+k +  s+ +++ +gt  Y 
  EEA20890.1 203 SRHVITQVAEAIEYLHeTSGVVHRDIKPENLLFYPtefvpskhpklrqpgdedkvdegdfiagvgaggIGKIKIADFGLSKVIWDSQ-TMTPCGTVGYT 300
                 ****************6667*************9548*************999999888887777666666*************998.9********** PP

                 -HHHHTTSCBSHHHHHHHHHHHHHHHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCT.SHH...HHHTTS-HHHHHHHHHHT-SSGCCSTTHHHHHTSG CS
     Pkinase 165 APEvlkeneyskkvDvWslGvilyelltgkppfsgekgkekvekeldqlekilkilg.etkeklpeaseiseeakdllkkllkkdpkkRltaeellqhp 262
                 APE++k+++ysk+vD+W+lG++ly++l+g ppf++e+      + l++     k+ + ++++ +p++++is+ a+dl++ ll++dp kR+t+++ l+hp
  EEA20890.1 301 APEIVKDERYSKSVDMWALGCVLYTILCGFPPFYDES-----IQVLTE-----KVARgQYTFLSPWWDDISKPAQDLVSHLLTVDPDKRYTIRQFLDHP 389
                 **********************************222.....233333.....44444899************************************** PP

                 GG CS
     Pkinase 263 yl 264
                 ++
  EEA20890.1 390 WV 391
                 *6 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  125.2   0.0   7.6e-40   2.7e-36       3     255 ..     105     385 ..     103     388 .. 0.89

  Alignments for each domain:
  == domain 1  score: 125.2 bits;  conditional E-value: 7.6e-40
                  EEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEEST.TSSHHHHHHHHHHHHHHHTS-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHTCTTT CS
  Pkinase_Tyr   3 lgkklGeGafGkVvegtlkgekekkevkVavKtlke.eateeekeelleeakimkklkhpnivkllgvctkeepllivteyvkgGdLlkfLrkkekek 99 
                  l +k+G Gaf++V++++ +    ++ ++Va+K++++ e+++++++++l+e++im++l+hpnivkl+ +  +++ ++iv+e+++gG+L + + +   + 
   EEA20890.1 105 LIQKMGDGAFSNVYRAKDT---LSQMEEVAIKVVRKfEMNRNQRANILKEVQIMRQLDHPNIVKLVDFSESSQFYYIVLELCPGGELFHQIVRL--TY 197
                  5789************988...78899*******662667777999*****************************************9999997..88 PP

                  SBHHHHHHHHHHHHHHHHHHHHTT.EEEST-SGGGEEEEE.................................TTEEEE-STTTHEETTTSSEEEETT CS
  Pkinase_Tyr 100 ltlkdllsfalqvAkGmeyLeskk.lvHrdlaarNvLlse.................................nkvvkisDfGLardiekddeyvkke 163
                  ++ +   ++++qvA+++eyL++ + +vHrd+   N L                                      ++ki+DfGL++ i +    +++ 
   EEA20890.1 198 FSEELSRHVITQVAEAIEYLHETSgVVHRDIKPENLLFYPtefvpskhpklrqpgdedkvdegdfiagvgaggIGKIKIADFGLSKVIWD----SQTM 291
                  99999999************987659************98899****************************98889************33....3333 PP

                  SSTSGGGGS-HHHHHHSEEEHHHHHHHHHHHHHHHHTTSSGTTTTSHHHHHHHHHHTTEE.S-BB..TTSBHHHHHHHHHHT-SSGGGS--HHHH CS
  Pkinase_Tyr 164 eaklpvkWmapEslkekkftsksDvWsfGvllwEiftlgespypglkneevleklkegkr.lekp..ekcpeelyelmkkcweedpeeRptfsel 255
                  +    v ++apE++k+++++++ D+W+ G +l+ i++ g  p+ + + + ++ek+ +g+     p  +++++  ++l+++ ++ dp++R t+++ 
   EEA20890.1 292 TPCGTVGYTAPEIVKDERYSKSVDMWALGCVLYTILC-GFPPFYDESIQVLTEKVARGQYtFLSPwwDDISKPAQDLVSHLLTVDPDKRYTIRQF 385
                  4456899*****************************9.*******99999999996665424444337889999999999999999999998876 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.1      0.21   7.6e+02      21      61 ..     110     151 ..     102     175 .. 0.53
   2 !    6.5   0.0    0.0013       4.5     142     179 ..     200     237 ..     186     242 .. 0.84
   3 !    8.8   0.0   0.00025      0.89     225     251 ..     308     334 ..     283     379 .. 0.78

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.21
  Kinase-like  21 kkgdrsvvfevkdqe.tgeplavkvfllpseaskkdlerlke 61 
                  ++g +s v+++kd   + e++a+kv    + + ++  + lke
   EEA20890.1 110 GDGAFSNVYRAKDTLsQMEEVAIKVVRKFEMNRNQRANILKE 151
                  555666666666653134555555544444333333333333 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0013
  Kinase-like 142 etiarlllTlqlirlaanLqa.kglvhgkftvdnlllde 179
                  e+++r+++T q+   + +L++  g+vh +++++nll+ +
   EEA20890.1 200 EELSRHVIT-QVAEAIEYLHEtSGVVHRDIKPENLLFYP 237
                  6789****6.699999***9636************9865 PP

  == domain 3  score: 8.8 bits;  conditional E-value: 0.00025
  Kinase-like 225 tkmthkldaWqlGlviyriwclklPlt 251
                   +++ ++d W+lG v y i c   P+ 
   EEA20890.1 308 ERYSKSVDMWALGCVLYTILCGFPPFY 334
                  568999***************988875 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   0.0    0.0048        17      32     108 ..     143     220 ..     106     222 .. 0.77
   2 ?    8.5   0.0   0.00049       1.8     156     181 ..     210     236 ..     187     243 .. 0.68
   3 ?   -2.9   0.3       1.5   5.3e+03     143     143 ..     573     573 ..     514     617 .. 0.44

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.0048
                 S-HHHHHHHHHHHHHHHHTT-B--B-CTTBS-EEETTEEEEEEE----EE-SS.....HHHHHHHHHHHHHHHHHHCCHHCH CS
         APH  32 raaeeirrevallrlLakagvpvPevlagdtddeeigllfalieyvpgrsllr.....klsaaqlpellealgeflaalhqv 108
                    + i +ev+++r+L   ++   +++++ ++ ++++++ +l ++  g+ +++     + s++ +++++ +++e++  lh++
  EEA20890.1 143 NQRANILKEVQIMRQLDHPNI--VKLVDFSESSQFYYIVLELCPG--GELFHQivrltYFSEELSRHVITQVAEAIEYLHET 220
                 446789999999999998877..5*****9999999998888888..77777799999999999999999999999888876 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00049
                 HHHH--S.SS-EEEE-SS-SGGGEEEC CS
         APH 156 laallpg.elptvllHgDlhpgNllvd 181
                 +a+     ++  +++H+D++p Nll+ 
  EEA20890.1 210 VAEAIEYlHETSGVVHRDIKPENLLFY 236
                 333222244799*************97 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 1.5
                 C CS
         APH 143 d 143
                  
  EEA20890.1 573 G 573
                 1 PP

>> Spa1_C  Lantibiotic immunity protein Spa1 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.3   9.9e-05      0.36      34      97 ..      61     139 ..      47     141 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 9.9e-05
      Spa1_C  34 viaelivvdetgkilskeelkkievsg..............eekseekreqlnygnVYsikgtske.eavaVeinneyr 97 
                 +++++ + d++++++s+++++k+  ++                   +k  +  + nVY++k+t ++ e+va+++  ++ 
  EEA20890.1  61 ALSQQTATDTKNNRISRADIEKLVAEErhskskmpiypgldRYILIQKMGDGAFSNVYRAKDTLSQmEEVAIKVVRKFE 139
                 5778888999************999999999999999998777889999999***********8877******988886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (620 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       806  (0.0449551); expected 358.6 (0.02)
Passed bias filter:                      456  (0.0254337); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.62u 0.25s 00:00:00.87 Elapsed: 00:00:00.42
# Mc/sec: 4448.03
//
Query:       EEA20891.1  [L=914]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (914 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1010  (0.0563333); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.71u 0.31s 00:00:01.02 Elapsed: 00:00:00.46
# Mc/sec: 6026.82
//
Query:       EEA20892.1  [L=496]
Description: MFS monocarboxylate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-37  129.3  62.6    2.8e-35  121.9  45.1    2.1  2  MFS_1     Major Facilitator Superfamily
    3.7e-10   39.3  39.6    1.5e-07   30.6  14.4    2.8  3  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.9  45.1   3.1e-39   2.8e-35       6     352 ..     113     446 ..     103     447 .. 0.85
   2 !   21.5   9.5     1e-08   9.3e-05      77     160 ..     387     477 ..     384     487 .. 0.77

  Alignments for each domain:
  == domain 1  score: 121.9 bits;  conditional E-value: 3.1e-39
       MFS_1   6 flsalarsilgpalplalaedlg...ispseigllltlyalgaavaslplGrlsdrfGrrr.vlllglllfalglllllfasslw.lllvlrvlqGlga 99 
                 f ++  ++++g++ + +++++ +   +s  +ig+++++ya ++++  l +G++ d  G+r  vl  ++l+++++ ++l f++ +w ++lv+ vl+G+g+
  EEA20892.1 113 FGAMGLINTIGTFQT-YISTH-QlkeYSSGTIGWIFGIYACLTFFCGLQIGPVFDAKGPRLlVLAGSVLIMVSM-IILGFCTKYWqFMLVFGVLMGVGT 208
                 333333333333333.34333.13469**********************************7777777777777.888899****************** PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeeekgtgpaplvp 198
                 +++f+ ++a++ ++f + +rg a+g++++g s+G i+ pl+  +l   +gW ++  ++a+++l++  l+++ ++ + + ++++++ke         ++p
  EEA20892.1 209 SLIFTPAIAAVGHYFYD-RRGEATGIAAMGGSVGGIVFPLVLEALFPKIGWAWATRVIALFCLIS--LGVACILIRSRLPPKPASKEN--------ILP 296
                 *****************.***********************************************..455555555555555555555........444 PP

       MFS_1 199 awkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavt 297
                     +++dp + +  ++++l+ +g++  +t++ +y     g+s    ++ +la+l +++a+++ l g+++d lgr ++++la l++l+++++l l a  
  EEA20892.1 297 -DFRIFRDPIFSLTTAGVFLIEWGMFVPVTYISSY-ALAEGFS-STFSYQILAILNVGSAFGRWLPGYIADYLGRFNTMILASLGCLVTSACLWLPAGG 392
                 .45567777664588888888889999********.*******.699999999999999999************************************* PP

       MFS_1 298 ssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfntagslggalg 352
                  s +ll++ +vl+Gf++g   ++  +++ +l+ +e+ g++++ + t+ s g++ g
  EEA20892.1 393 -SLALLIVYSVLFGFFSGSNISLTPVCVGQLCKTEHYGRYYATAYTIVSMGTLTG 446
                 .89999999****************************************998866 PP

  == domain 2  score: 21.5 bits;  conditional E-value: 1e-08
       MFS_1  77 llllfasslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg........Wravfyilaiv 160
                 +l++   ++  ll+v  vl G+++g+ +++  + + ++ + e+ gr+++ +++ +s+G++ g +++g ++s  g        + a+ y+ +++
  EEA20892.1 387 WLPA--GGSLaLLIVYSVLFGFFSGSNISLTPVCVGQLCKTEHYGRYYATAYTIVSMGTLTGVPIAGEILSRCGghywgliaFVACCYFSGAI 477
                 3333..56666***************************************************9999988888886763333333333333333 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4  11.6   8.8e-08   0.00079      16     118 ..     116     210 ..     102     219 .. 0.86
   2 ?   -0.6   0.2     0.053   4.7e+02     387     435 ..     230     278 ..     223     282 .. 0.50
   3 !   30.6  14.4   1.7e-11   1.5e-07      44     177 ..     337     469 ..     306     484 .. 0.85

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 8.8e-08
                 HHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHH CS
    Sugar_tr  16 tgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGi 114
                 +g+i+++ t++ +++ ++l++++s +      +g+i++i+    ++ +l +g++ d  G +   l+++vl +++ ++ ++++++  ++ ++v  vl+G+
  EEA20892.1 116 MGLINTIGTFQTYISTHQLKEYSSGT------IGWIFGIYACLTFFCGLQIGPVFDAKGPRLLVLAGSVLIMVSMIILGFCTKY--WQFMLVFGVLMGV 206
                 68899999999999999999999866......59************************************************44..6666777899988 PP

                 HHHH CS
    Sugar_tr 115 gvGl 118
                 g  l
  EEA20892.1 207 GTSL 210
                 7655 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.053
                 HHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHH CS
    Sugar_tr 387 alaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvff 435
                 a+ ia++   +  ++  l+   ++ +ig ++   v a ++++++ + ++
  EEA20892.1 230 ATGIAAMGGSVGGIVFPLVLEALFPKIGWAWATRVIALFCLISLGVACI 278
                 5555555555555555555555555555444444444444444444444 PP

  == domain 3  score: 30.6 bits;  conditional E-value: 1.7e-11
                 ...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHH CS
    Sugar_tr  44 ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvsl 142
                 ss+ s  i++i++vG+++G  + g+++d++GR ++++ a++ +++ +++  +  g+ s+ +liv  vl G++ G    l+P+ ++ ++++++ g+    
  EEA20892.1 337 SSTFSYQILAILNVGSAFGRWLPGYIADYLGRFNTMILASLGCLVTSACLWLPAGG-SLALLIVYSVLFGFFSGSNISLTPVCVGQLCKTEHYGRYYAT 434
                 666677799****************************************9999966.****************************************** PP

                 HHHHHHHHHHHHHHHHHHH.HTSS-TTHHHHHHHCC CS
    Sugar_tr 143 yqlaitfGilvaaifglgl.nktsnadgwrillglq 177
                   + +++G l +  +   + +++++   w +  +++
  EEA20892.1 435 AYTIVSMGTLTGVPIAGEIlSRCGG-HYWGLIAFVA 469
                 ***********98666555599999.6666554443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (496 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       712  (0.0397122); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.23s 00:00:00.81 Elapsed: 00:00:00.42
# Mc/sec: 3543.35
//
Query:       EEA20893.1  [L=210]
Description: hypothetical protein PMAA_047080 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (210 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       237  (0.0132188); expected 358.6 (0.02)
Passed bias filter:                      107  (0.00596798); expected 358.6 (0.02)
Passed Vit filter:                         7  (0.000390429); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.47
# Mc/sec: 1332.67
//
Query:       EEA20894.1  [L=330]
Description: tricarboxylate transport protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.8e-64  213.7   1.7    4.9e-22   77.7   0.0    3.0  3  Mito_carr  Mitochondrial carrier protein


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.7   0.0   2.7e-26   4.9e-22       3      96 ..      12     106 ..      10     107 .. 0.92
   2 !   57.4   0.3   5.9e-20   1.1e-15       8      95 ..     116     207 ..     110     209 .. 0.90
   3 !   76.9   0.0   4.9e-26   8.8e-22       2      92 ..     224     314 ..     223     318 .. 0.95

  Alignments for each domain:
  == domain 1  score: 77.7 bits;  conditional E-value: 2.7e-26
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSS.HHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCTT CS
   Mito_carr   3 lsvlkellaGglagavatlvttPldvvKtrlqtqkksskksksaa.ildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlllkk 96 
                 +s++ +l+aGg ag+ ++lv++Pld++K+r+q++++ ++     + ++ +   i+++eG+ gly Gl++ + +++p+ a++f++ye++krll++k
  EEA20894.1  12 TSIATTLIAGGGAGMSEVLVCHPLDTIKVRMQLSRRANRFGPPPQgVVGTAVGIVRNEGFFGLYNGLGAVIGGIIPKMAIRFTSYEYYKRLLTDK 106
                 678999***************************9999876443337*********************************************9875 PP

  == domain 2  score: 57.4 bits;  conditional E-value: 5.9e-20
                 HHHHHHHHHHH.HHHHHHHHHHHHHHHHH...CCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCT CS
   Mito_carr   8 ellaGglagav.atlvttPldvvKtrlqt...qkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlllk 95 
                 ++laG++ag++ a++v++ ++v+K+rlq+   +++ +   k++++ +++++++++eG++ l+rG++ + lr+  ++a++f++y  lk+ l+k
  EEA20894.1 116 TFLAGLAAGITeAVTVVNAVEVIKIRLQAlhkAPNGALVPKYKGTSEAISTLIRTEGISFLWRGVTLTALRQGTNQAANFTVYTELKTGLQK 207
                 79*********8899**************655555566677777*******************************************99876 PP

  == domain 3  score: 76.9 bits;  conditional E-value: 4.9e-26
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   2 elsvlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrl 92 
                 el+ +++ ++G+++gav+ ++ +P+d++Ktr+q ++    ks  ++i+ +   ++++eG r++y+G++p+++rvap +a++f++ye+lk  
  EEA20894.1 224 ELPSYQTTIIGLISGAVGPFFNAPIDTIKTRIQQAPVIPGKSSLSHIMTITTDMLRNEGARSFYKGITPRVMRVAPGQAVTFTVYEFLKGR 314
                 67789999********************************999999*****************************************9965 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (330 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       590  (0.0329076); expected 358.6 (0.02)
Passed bias filter:                      493  (0.0274974); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.31s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2193.30
//
Query:       EEA20895.1  [L=315]
Description: D-3-phosphoglycerate dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.8e-53  180.5   0.0    2.6e-53  180.0   0.0    1.2  1  2-Hacid_dh_C   D-isomer specific 2-hydroxyacid dehydrogenase,
    9.9e-22   77.0   0.1    1.4e-21   76.6   0.1    1.2  1  2-Hacid_dh     D-isomer specific 2-hydroxyacid dehydrogenase,
    3.5e-06   27.3   0.0    6.2e-06   26.5   0.0    1.4  1  NAD_binding_2  NAD binding domain of 6-phosphogluconate dehyd
    0.00034   21.1   0.0    0.00084   19.9   0.0    1.7  1  F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
  ------ inclusion threshold ------
      0.034   14.5   0.1       0.17   12.2   0.0    2.1  2  Gp_dh_N        Glyceraldehyde 3-phosphate dehydrogenase, NAD 
       0.07   13.0   0.0       0.12   12.2   0.0    1.4  1  3HCDH_N        3-hydroxyacyl-CoA dehydrogenase, NAD binding d
       0.11   13.3   0.0       0.24   12.2   0.0    1.6  1  GFO_IDH_MocA   Oxidoreductase family, NAD-binding Rossmann fo


Domain annotation for each model (and alignments):
>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  180.0   0.0     1e-56   2.6e-53       1     178 []     103     283 ..     103     283 .. 0.95

  Alignments for each domain:
  == domain 1  score: 180.0 bits;  conditional E-value: 1e-56
                   HHHHHHHHTTHHHHHHHHHTTCCHTTCCGSBS-GTTSEEEEES-SHHHHHHHHHHH.HTT-EEEEESSSHHHHHCHHHHTCEECSHHHHHHH-SEEE CS
  2-Hacid_dh_C   1 lalllallrrlaeadeevregewksekallgkelsgktvGiiGlGrIGqavakrlk.afgmkviaydrskkkeeeeeelgvelvsleellaesDivs 96 
                   +al+l l+rr+ e+d++vr+g+   ++++l++++ +k+vG+iG+G+IG+ +a++   af+++v+ayd+s  +++ +  ++v++  l++ll+++D+++
    EEA20895.1 103 MALALTLSRRVCEIDRAVRSGQRVIRSTMLSTSMFRKRVGVIGMGNIGKIIAQKWIgAFECEVVAYDPSAPADAWKGLNHVRVKALDDLLKDADVIT 199
                   6899*****************9999***************************99877************998885555667999************* PP

                   E-S--STTTTTSBSHHHHHCSTTTEEEEESS-GGGB-HHHHHHHHHTTSCCEEEES--SSSSSGTC..HHHHHSTTEEE-SS-T CS
  2-Hacid_dh_C  97 lhlpltpetrhlinaeelakmkkgailiNtaRGglvdeeaLleaLksgkiagaalDvfeeeplped..spllelpnviltPHia 178
                   lh+pl ++tr li+++el+ mk +ail+N+aRGg+v+e+aLl+aL+++ki+gaalDv+e ep++ d   ++l+++nvi+tPHi+
    EEA20895.1 200 LHVPLLESTRSLISDHELSIMKANAILVNCARGGVVEEKALLRALDQKKIGGAALDVMEIEPPTLDvyGEFLKHENVIMTPHIG 283
                   ***************************************************************9885569************98 PP

>> 2-Hacid_dh  D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.6   0.1   5.4e-25   1.4e-21      35     130 ..      35     311 ..       6     314 .. 0.95

  Alignments for each domain:
  == domain 1  score: 76.6 bits;  conditional E-value: 5.4e-25
                 HHHTTESEEEE-TTS-BSHHHHHHHTT--EEEESSSSCTTB-HHHHHHTT-EEEE-TTTTHHHHHHHH............................... CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............................... RF
  2-Hacid_dh  35 ekakdadalivrsntkvtaevlealpkLkviaragvGvDnvDldaakerGilVtnvpgystesvAElt............................... 102
                    +dad++++rs +++t++ ++++  L+ ++  gvGvDn+Dl+  k++Gi+V n+p+ ++esvAEl                                
  EEA20895.1  35 HWHADADGIMIRSDSRLTEADFAQAACLRAVVKQGVGVDNIDLAGSKKHGIAVHNTPTLNSESVAELSmalaltlsrrvceidravrsgqrvirstmls 133
                 34569********************************************************************************************** PP

                 ................................................................................................... CS
                 ................................................................................................... RF
  2-Hacid_dh 103 ................................................................................................... 102
                                                                                                                    
  EEA20895.1 134 tsmfrkrvgvigmgnigkiiaqkwigafecevvaydpsapadawkglnhvrvkalddllkdadvitlhvpllestrslisdhelsimkanailvncarg 232
                 *************************************************************************************************** PP

                 ...................................................T-BHHHHHHHHHHHHHHHHHHHTTCCGT CS
                 ...................................................xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  2-Hacid_dh 103 ...................................................aaTeeaqeniaeeaaenlvaflkgespa 130
                                                                    + T+e q++ ++ ++e l+++l+g++++
  EEA20895.1 233 gvveekallraldqkkiggaaldvmeiepptldvygeflkhenvimtphigGCTKENQSRTGMAVVETLMDVLEGREAT 311
                 ***************************************************************************8765 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.5   0.0   2.4e-09   6.2e-06       1     109 [.     140     249 ..     140     256 .. 0.90

  Alignments for each domain:
  == domain 1  score: 26.5 bits;  conditional E-value: 2.4e-09
                    EEEEE--SHHHHHHHHHHH.HTT-EEEEE-SSHHHHHHHHHTTEEE-SSHHHHHHHCSEEEE-SSSHHHHHHHHHS.HCCC--TT-EEEE-S---H CS
  NAD_binding_2   1 kigfiGlGvMGsnmalnll.kagykvavynrtkekveelvaegakaaesieelvasldvvitmvkagkavdevieg.llealkkgdilidgstssp 94 
                    ++g+iG+G++G+ +a++ + + +++v++y+ + + ++++   + + ++ + +l++++dv+ + v+  + ++++i++  l+ +k+++il++++   +
     EEA20895.1 140 RVGVIGMGNIGKIIAQKWIgAFECEVVAYDPS-APADAWKGLNHVRVKALDDLLKDADVITLHVPLLESTRSLISDhELSIMKANAILVNCARGGV 234
                    58***************9736699******88.889999999999******************************9888999********999888 PP

                    HHHHHHHHHHHHTT- CS
  NAD_binding_2  95 edtrelakelkekgl 109
                     + + l ++l +k++
     EEA20895.1 235 VEEKALLRALDQKKI 249
                    888888888888765 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   0.0   3.3e-07   0.00084       1      71 [.     140     204 ..     140     232 .. 0.76

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 3.3e-07
                    EEEEETTSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC-EEECECHHHHHHH-SEEEE-S-H CS
  F420_oxidored   1 kigiiGaGnmgealasgllaagaqpheivvansrnpekaeelaeelgvkvtavdneeaaeeadvvvlavkp 71 
                    ++g+iG+Gn+g+ +a++++ a   + e+v a +++   a++++    v+v+a    +++++adv+ l v+ 
     EEA20895.1 140 RVGVIGMGNIGKIIAQKWIGAF--ECEVV-AYDPS-APADAWKGLNHVRVKA--LDDLLKDADVITLHVPL 204
                    69*****************997..77888.74444.4477777777777777..99***********9996 PP

>> Gp_dh_N  Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0       1.1   2.8e+03      68      85 ..      21      38 ..       6      50 .. 0.73
   2 ?   12.2   0.0   6.8e-05      0.17       2      30 ..     140     168 ..     139     183 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 1.1
                EEEEEE--SSGGGS-CHH CS
     Gp_dh_N 68 kkikvlaekdpeelpwke 85
                 +++v+  +dp++ +w++
  EEA20895.1 21 PHVQVIIPNDPRKAHWHA 38
                589999999999999975 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 6.8e-05
                 EEEEESTSHHHHHHHHHHHHHTTCEEEEE CS
     Gp_dh_N   2 kvainGfGRIGrlvlralleekelevvai 30 
                 +v++ G+G IG++++++++   e+evva 
  EEA20895.1 140 RVGVIGMGNIGKIIAQKWIGAFECEVVAY 168
                 89************************986 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   4.7e-05      0.12       2      32 ..     141     172 ..     140     203 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 4.7e-05
                 EEEE--SCCHHHHHHHHHHT.T-EEEEE-S-H CS
     3HCDH_N   2 vaviGaGtmGagiaavfasa.gleVvlvdise 32 
                 v+viG G +G+ ia+  + a ++eVv +d s+
  EEA20895.1 141 VGVIGMGNIGKIIAQKWIGAfECEVVAYDPSA 172
                 9****************9999********954 PP

>> GFO_IDH_MocA  Oxidoreductase family, NAD-binding Rossmann fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   9.3e-05      0.24       2      73 ..     140     210 ..     139     228 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 9.3e-05
                   EEEEETTSHHHHHHHHHHHHTTTTEEEEEEECSSHHHHHHHHHHTTHEEESSHHHHHTCTTESEEEE-S-G.....G CS
  GFO_IDH_MocA   2 rvaiiGaGkigskhlrplnesqrleevvalldpdaeraeavaesfgveaysdleelladpeidavivatpn.....g 73 
                   rv++iG+G+ig+  ++++  ++++e v+  +dp+a++     + +++  ++ l++ll+  ++d+++  +p      +
    EEA20895.1 140 RVGVIGMGNIGKIIAQKWIGAFECEVVA--YDPSAPADA--WKGLNHVRVKALDDLLK--DADVITLHVPLlestrS 210
                   8********************7776554..888885544..57788888899999999..78888888886555443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (315 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       393  (0.0219198); expected 358.6 (0.02)
Passed bias filter:                      345  (0.0192426); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.50u 0.29s 00:00:00.79 Elapsed: 00:00:00.47
# Mc/sec: 2015.91
//
Query:       EEA20896.1  [L=136]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-28  100.4   0.0    1.3e-28  100.2   0.0    1.0  1  Ldh_2     Malate/L-lactate dehydrogenase


Domain annotation for each model (and alignments):
>> Ldh_2  Malate/L-lactate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.2   0.0     7e-33   1.3e-28     218     332 ..       1     116 [.       1     117 [. 0.96

  Alignments for each domain:
  == domain 1  score: 100.2 bits;  conditional E-value: 7e-33
                 E-BTTTHHHHHHHHHHHHHHTCTTTS-HGGGSSSSSSCTSS-SSEEEEEEEEEGGGTT..HHHHHHHHHHHHHHHHTS-BSTTTSS---TTHHHHHHHH CS
       Ldh_2 218 llplGghKGyglalmvelLagvLsgaatgkevsgsedeekkpaklghffiaidpeafgd.aeefkervdalldelrasppaegadevllPGereaaara 315
                 +lp+Gg+KG+gla+m+++++++L+ ++++ +v+++++++++p+ +gh+f++++pe f d ++e+++r+d+ll ++r ++++eg d++++PGe+  +++ 
  EEA20896.1   1 MLPIGGAKGSGLAMMMDIFGALLTASSFAGDVNDQYNNTRNPQGVGHWFMVFKPETFLDsRDELADRMDTLLGRVRPCEKVEGVDRIRVPGENATEMET 99 
                 79**********************************999999999************7669************************************** PP

                 HHHHH-EEEEHHHHHHH CS
       Ldh_2 316 erlkeGipldeavleel 332
                 +r+ eGip  +  l++l
  EEA20896.1 100 RRRFEGIPFTAVELKNL 116
                 *********99888877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (136 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       256  (0.0142785); expected 358.6 (0.02)
Passed bias filter:                      242  (0.0134977); expected 358.6 (0.02)
Passed Vit filter:                         9  (0.00050198); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.20s 00:00:00.59 Elapsed: 00:00:00.38
# Mc/sec: 1066.49
//
Query:       EEA20897.1  [L=586]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.3e-46  159.2  26.2      2e-44  151.9  28.1    2.3  2  MFS_1       Major Facilitator Superfamily
    2.1e-14   52.9  18.4      3e-14   52.4  18.4    1.1  1  TRI12       Fungal trichothecene efflux pump (TRI12)
    2.9e-11   42.9  13.3    7.7e-11   41.5  13.3    1.7  1  Sugar_tr    Sugar (and other) transporter
    3.4e-06   26.2   1.7    3.4e-06   26.2   1.7    2.9  3  MFS_1_like  MFS_1 like family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  151.9  28.1   4.5e-48     2e-44       1     278 [.      66     390 ..      66     416 .. 0.88
   2 !    3.0   0.0    0.0088        39     144     184 ..     511     546 ..     488     572 .. 0.75

  Alignments for each domain:
  == domain 1  score: 151.9 bits;  conditional E-value: 4.5e-48
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlga 99 
                 ++la+++s+l+ +++++a+p a++e+l++ ps i++++t + l++   +l+ Grlsd +Gr+++ll+++ ++a + l++ fa++  +l+++r ++Glg+
  EEA20897.1  66 IALAQMISYLDQTCISTAVP-AIGESLNMGPS-ISWIATSFLLASTSIQLVNGRLSDIVGRKPLLLICMGILAGANLCAGFAQNAAMLFAFRSIAGLGG 162
                 689*****************.*******6666.9*****************************************77777966655************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 ga++++++++++d+++ e+rg+++g+++a+++lG  +gpl+gg+l+++++Wr++f+++ +v ++++v   +   + pp+  r + ++++          
  EEA20897.1 163 GAITALVMIIASDITTLEQRGKYNGFIGAMVGLGNGIGPLIGGALTQHASWRWCFWFIVPVIVVVMV---VIAIVIPPSTVRGNAWTKLrmldwlglvm 258
                 *****************************************************************99...5555556666666666666799******* PP

       MFS_1 189 ............................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsgl 243
                                                              + ++ p+ p ++++ +d+   ++++   l ++++++ l+++p+ylq+v+g+s  
  EEA20897.1 259 nvgavvlvlipisqggstypwdgtlviamltisglliitfvlveWKFAKLPMMP-IRLFQSDKSANLVFLQGTLHGVVYWANLFYIPMYLQTVRGYSPI 356
                 **********************************99999999888888888888.9999999977568888888899********************43 PP

       MFS_1 244 llaglllallalvgailallagrlsdrlgrrrrll 278
                 l+++++l+++a  g +++l++g ++ ++g+  +l 
  EEA20897.1 357 LSGAIILPMVASHG-VGSLVSGHIISKTGHYGPLR 390
                 44444444444444.5689********99876665 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.0088
       MFS_1 144 lasslgWravfyilaivsllafvlfllllpeepperkrksp 184
                 +a   g + +f++ a++  ++fv+  ++l +++   ++++ 
  EEA20897.1 511 MA---GMHTIFVMYAPIIGVCFVC--AVLIRDEGVAEKDAR 546
                 44...8999**************9..555555444444433 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.4  18.4   6.8e-18     3e-14      42     335 ..      59     348 ..      44     373 .. 0.79

  Alignments for each domain:
  == domain 1  score: 52.4 bits;  conditional E-value: 6.8e-18
       TRI12  42 vvasfaafslnvvatyfvlqasasalpnilqdvgqsensslfstlwttgqavsilvmgrltdrfgrrpfvilthilglvga.ivgctatkfntllaamt 139
                 ++  f +++l  + +y+   + ++a+p i + +      s ++t + +  +   lv grl+d +gr+p++++   + l ga +    a++   l+a  +
  EEA20897.1  59 LMIVFPTIALAQMISYLDQTCISTAVPAIGESLNMGPSISWIATSFLLASTSIQLVNGRLSDIVGRKPLLLICMGI-LAGAnLCAGFAQNAAMLFAFRS 156
                 6667888888889999988889999****9999999999999**9999999999**************98876544.4455144445677778888899 PP

       TRI12 140 llgvaagpagasplfvge...lmsnktkflgllivsipvvvtsglspylgqrlaiqgswrwifyiyiitsaiavllivvwyyppsfaqlhgkkvrkree 235
                 + g+  g   a  +++      + ++ k+ g++   + v   +g++p +g  l+   swrw f+ +i+   + v++++    pps   + g+      +
  EEA20897.1 157 IAGLGGGAITALVMIIASditTLEQRGKYNGFI--GAMVGLGNGIGPLIGGALTQHASWRWCFW-FIVPVIVVVMVVIAIVIPPST--VRGNAW---TK 247
                 999999999999999875222356788999975..55666789*******************98.455555566666667789986..456554...45 PP

       TRI12 236 lakldwigiilvivgvslfllgvswggkpnspwnsakviglissglgslvvfalyevygkpvrpivppalfkdtrgfvcillissimgam...nlslvi 331
                 l  ldw+g+++ +  v l+l+ +s gg    pw+ + vi +++     ++ f l e +   + p++p  lf+  +    ++l  ++ g +   nl  + 
  EEA20897.1 248 LRMLDWLGLVMNVGAVVLVLIPISQGGS-TYPWDGTLVIAMLTISGLLIITFVLVE-WKFAKLPMMPIRLFQSDKSANLVFLQGTLHGVVywaNLFYIP 344
                 8899**********************97.57*********9997655566677777.556678*********999988888888877776221344444 PP

       TRI12 332 iypq 335
                 +y q
  EEA20897.1 345 MYLQ 348
                 5544 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.5  13.3   1.7e-14   7.7e-11      47     195 ..      96     240 ..      49     247 .. 0.90

  Alignments for each domain:
  == domain 1  score: 41.5 bits;  conditional E-value: 1.7e-14
                 HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHH CS
    Sugar_tr  47 lsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyql 145
                  +++i+ +fl+ ++  +l+ g l+d++GRk+ lli+  ++  ++++ ++a+   +  +l++ R ++G+g G++++lv + +s i++ + Rg+  ++   
  EEA20897.1  96 SISWIATSFLLASTSIQLVNGRLSDIVGRKPLLLICMGILAGANLCAGFAQ---NAAMLFAFRSIAGLGGGAITALVMIIASDITTLEQRGKYNGFIGA 191
                 579************************************************...99******************************************* PP

                 HHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---H CS
    Sugar_tr 146 aitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESP 195
                 ++ +G  ++  +g +l +  + ++w++ + + ++  ++++i+++  P + 
  EEA20897.1 192 MVGLGNGIGPLIGGALTQHAS-WRWCFWFIVPVIVVVMVVIAIVIPPSTV 240
                 *************99988888.8899888899998888888777777665 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.2   1.7   7.5e-10   3.4e-06     270     384 ..     105     218 ..      13     219 .. 0.79
   2 ?    2.1   2.0     0.015        69     183     289 ..     287     385 ..     221     401 .. 0.68
   3 ?   -0.9   0.3      0.12   5.5e+02     154     236 ..     455     533 ..     449     543 .. 0.59

  Alignments for each domain:
  == domain 1  score: 26.2 bits;  conditional E-value: 7.5e-10
  MFS_1_like 270 vvaeiplfffaeklleklGhvklliiallayilrfllyaiienawlvlpievLhgisfgllwaaaveyvskiapksleatgqgllsglyfglGralGsl 368
                  +a+  + +++ +l +++G   ll+i++ + +   l  ++ +na +++ +  + g+  g++ a ++  +s+i++ + ++++ g++ ++ +glG+++G l
  EEA20897.1 105 LLASTSIQLVNGRLSDIVGRKPLLLICMGILAGANLCAGFAQNAAMLFAFRSIAGLGGGAITALVMIIASDITTLEQRGKYNGFIGAM-VGLGNGIGPL 202
                 456777888999******************99999999***********************99999*****************98766.9********* PP

  MFS_1_like 369 iGGllwdlksaiflFr 384
                 iGG+l ++ s ++ F 
  EEA20897.1 203 IGGALTQHASWRWCFW 218
                 **********999996 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.015
  MFS_1_like 183 lyvlaallvisllvvlilnetekesklkvtkslqvllnilknpeviif.llvalilgmswgiienFlflYL.kelgasntllGslvalgvvaeiplfff 279
                 ++++ +ll+i++++       +k  kl ++      +++++  + + + +l  ++ g+++ +   ++ +YL    g+s +l G+++   v++  +  ++
  EEA20897.1 287 MLTISGLLIITFVL-----VEWKFAKLPMM-----PIRLFQSDKSANLvFLQGTLHGVVYWANLFYIPMYLqTVRGYSPILSGAIILPMVASHGVGSLV 375
                 33333333333333.....33333344433.....4666666666554033344445554444567889996677999999999888877777777777 PP

  MFS_1_like 280 aeklleklGh 289
                 +  ++ k+Gh
  EEA20897.1 376 SGHIISKTGH 385
                 7888888887 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 0.12
  MFS_1_like 154 GsvGyaifafitGilidhysvnllpysallyvlaallvisllvvlilnetekesklkvtkslqvllnil.knpeviifllvali 236
                 GsvG  i+ +i+   + +  +n+lp+ ++  +  + + +s++  l++n+ e   +  ++     +  i+ +   +i++++v+++
  EEA20897.1 455 GSVGLTISGTILNNTLKTQLRNTLPLDVINTITSSAYSLSSIN-LSPNQYEMVMDAYMAG----MHTIFvMYAPIIGVCFVCAV 533
                 8888888888888888888888888544444444444444444.5666666655555553....22233022335555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (586 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       779  (0.0434492); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.66u 0.31s 00:00:00.97 Elapsed: 00:00:00.46
# Mc/sec: 3802.13
//
Query:       EEA20898.1  [L=1313]
Description: two-component osmosensing histidine kinase (Bos1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.2e-42  144.0  15.5    1.5e-08   34.9   0.0    7.5  7  HAMP             HAMP domain
    2.9e-33  114.7   0.4    2.2e-32  111.9   0.1    2.6  2  HATPase_c        Histidine kinase-, DNA gyrase B-, and HSP90-
    1.2e-25   89.8   0.9    4.6e-25   88.0   0.5    2.3  1  Response_reg     Response regulator receiver domain
    4.6e-16   58.6   5.0    4.9e-16   58.5   0.1    3.8  3  HisKA            His Kinase A (phospho-acceptor) domain
    1.1e-11   44.5   6.6      0.026   13.7   0.0    5.6  4  APG17            Autophagy protein Apg17
    4.6e-07   30.1  13.0       0.73   10.2   0.0    6.6  5  Syntaxin_2       Syntaxin-like protein
    4.6e-05   23.6   0.0         13    6.0   0.0    5.5  5  DUF4279          Domain of unknown function (DUF4279)
     0.0021   18.3  53.1        1.6    9.1   0.2    9.9  5  DUF948           Bacterial protein of unknown function (DUF94
     0.0029   17.7   5.1     0.0029   17.7   5.1    6.9  5  Baculo_PEP_C     Baculovirus polyhedron envelope protein, PEP
      0.004   17.3  24.4        3.2    8.1   0.7    8.1  7  WXG100           Proteins of 100 residues with WXG
  ------ inclusion threshold ------
      0.013   16.0   5.0         27    5.4   0.0    5.9  5  DUF1843          Domain of unknown function (DUF1843)
      0.022   14.3  15.2       0.17   11.3   0.6    5.0  6  DUF3829          Protein of unknown function (DUF3829)
      0.023   15.0   4.9         45    4.4   0.1    4.9  5  Gp-FAR-1         Nematode fatty acid retinoid binding protein
      0.027   14.7  30.4       0.87    9.8   0.7    7.2  7  Fib_alpha        Fibrinogen alpha/beta chain family
       0.03   13.9  22.4        1.1    8.9   6.9    4.9  4  DUF4795          Domain of unknown function (DUF4795)
      0.043   13.4   0.0        6.2    6.5   0.0    2.7  2  NOD              NOTCH protein
      0.088   12.4   0.1       0.28   10.8   0.1    1.8  1  IcmF_C           Type VI secretion protein IcmF C-terminal
      0.096   12.7   2.5        2.1    8.4   0.1    2.8  2  PA-IL            PA-IL-like protein
       0.11   12.6   0.3         13    5.9   0.0    3.5  3  CMD              Carboxymuconolactone decarboxylase family
       0.12   11.5  17.3       0.22   10.6  17.3    1.3  1  DUF2457          Protein of unknown function (DUF2457)
       0.29   11.2  31.4       0.68   10.0   0.1    8.2  7  CENP-F_leu_zip   Leucine-rich repeats of kinetochore protein 
       0.37   10.0   9.4         17    4.5   0.0    4.3  5  GLE1             GLE1-like protein
       0.76    7.8  20.3       0.13   10.4  16.4    1.6  2  DNA_pol_phi      DNA polymerase phi
       0.91    9.4   6.4         26    4.7   0.0    4.8  4  DUF1759          Protein of unknown function (DUF1759)
        1.4    9.3  20.9         17    5.8   3.4    4.3  1  Fez1             Fez1
        1.6    8.8  14.5        3.5    7.7  14.5    1.5  1  YL1              YL1 nuclear protein
        1.7    7.2  29.1      0.061   12.0   4.8    4.0  4  AAA_13           AAA domain
        2.5    8.3  12.4         26    5.0   0.1    5.3  5  BORCS6           BLOC-1-related complex sub-unit 6
        2.7    7.8  34.3        3.4    7.4   2.7    6.2  5  Mer2             Mer2
        3.6    8.3   9.4         57    4.5   0.1    5.0  4  DUF5593          Domain of unknown function (DUF5593)
          4    6.9  11.0         12    5.4  11.0    1.8  1  PPP4R2           PPP4R2
        4.8    7.2  10.7         17    5.4  10.7    1.9  1  RXT2_N           RXT2-like, N-terminal
        5.6    6.9  13.8         17    5.3   0.1    5.5  6  Phage_Mu_Gam     Bacteriophage Mu Gam like protein
        6.4    6.9  11.9         40    4.4   0.2    5.9  5  SpoIIID          Stage III sporulation protein D
        7.4    6.7  17.3        2.7    8.2  14.3    1.8  1  RNA_pol_3_Rpc31  DNA-directed RNA polymerase III subunit Rpc3


Domain annotation for each model (and alignments):
>> HAMP  HAMP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.0     0.038        19      10      52 ..     219     264 ..     216     265 .. 0.89
   2 !   33.6   0.1   7.6e-11   3.9e-08       2      52 ..     306     356 ..     305     357 .. 0.96
   3 !   27.8   0.0   4.9e-09   2.5e-06       2      53 .]     398     449 ..     397     449 .. 0.97
   4 ?   -0.3   0.0       2.8   1.4e+03      40      52 ..     483     495 ..     482     496 .. 0.86
   5 !   30.9   0.4     5e-10   2.6e-07       2      52 ..     490     540 ..     489     541 .. 0.95
   6 !   34.9   0.0   2.9e-11   1.5e-08       2      51 ..     582     631 ..     581     633 .. 0.95
   7 !   15.8   0.1   2.6e-05     0.013      15      53 .]     687     725 ..     674     725 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.038
                 HHHHHHHHHHHTTTBTSST..CCT.TSSSHHHHHHHHHHHHHHHHH CS
        HAMP  10 LrrLaraarriaaGdldtr..lpv.sgrDEiGeLarafNaMldrLr 52 
                 Lr++   + ++a+Gdl+    + + + + Ei++  r++N+M+d+L+
  EEA20898.1 219 LREIGGIITQVANGDLSMKvqIHPlEMDPEIATFKRTINTMMDQLQ 264
                 6777777899****9999988999999*****************97 PP

  == domain 2  score: 33.6 bits;  conditional E-value: 7.6e-11
                 HHHTTHHHHHHHHHHHHHHTTTBTSSTCCTTSSSHHHHHHHHHHHHHHHHH CS
        HAMP   2 larrilrPLrrLaraarriaaGdldtrlpvsgrDEiGeLarafNaMldrLr 52 
                 +a++++  +r++a+++ ++a+Gdl++ ++ +   Ei eL +++N+M+d+Lr
  EEA20898.1 306 MAKNLTDQVREIATVTTAVAHGDLSQKIESRAHGEIFELQQTINTMVDQLR 356
                 78999999******************************************8 PP

  == domain 3  score: 27.8 bits;  conditional E-value: 4.9e-09
                 HHHTTHHHHHHHHHHHHHHTTTBTSSTCCTTSSSHHHHHHHHHHHHHHHHHH CS
        HAMP   2 larrilrPLrrLaraarriaaGdldtrlpvsgrDEiGeLarafNaMldrLre 53 
                 +a++++  +r +a +++++a+Gdl++ +  + + Ei+eL   +N M+d+Lr+
  EEA20898.1 398 MANNLTTQVRDIANVTKAVAKGDLTQKVQANCKGEIAELKNIINSMVDQLRQ 449
                 78999*********************************************97 PP

  == domain 4  score: -0.3 bits;  conditional E-value: 2.8
                 HHHHHHHHHHHHH CS
        HAMP  40 LarafNaMldrLr 52 
                 L +++N+M+++L 
  EEA20898.1 483 LTENVNRMANNLT 495
                 8899******995 PP

  == domain 5  score: 30.9 bits;  conditional E-value: 5e-10
                 HHHTTHHHHHHHHHHHHHHTTTBTSSTCCTTSSSHHHHHHHHHHHHHHHHH CS
        HAMP   2 larrilrPLrrLaraarriaaGdldtrlpvsgrDEiGeLarafNaMldrLr 52 
                 +a++++  +r++a+++ ++a+Gdl+  ++ + + Ei +L  ++N+M+drL+
  EEA20898.1 490 MANNLTTHVREIAEVTTAVAKGDLTRKVTANVQGEILDLKNTINDMVDRLN 540
                 788899999*****************************************8 PP

  == domain 6  score: 34.9 bits;  conditional E-value: 2.9e-11
                 HHHTTHHHHHHHHHHHHHHTTTBTSSTCCTTSSSHHHHHHHHHHHHHHHH CS
        HAMP   2 larrilrPLrrLaraarriaaGdldtrlpvsgrDEiGeLarafNaMldrL 51 
                 +a +++  +r +++++++ia+Gdl++ ++v+ + Ei +L  ++N+M+drL
  EEA20898.1 582 MAQNLTSQVRGISDVTQAIAKGDLSKKIEVHAQGEILTLKVTINNMVDRL 631
                 57789999*****************************************9 PP

  == domain 7  score: 15.8 bits;  conditional E-value: 2.6e-05
                 HHHHHHTTTBTSSTCCTTSSSHHHHHHHHHHHHHHHHHH CS
        HAMP  15 raarriaaGdldtrlpvsgrDEiGeLarafNaMldrLre 53 
                 + +++  +Gd+++ ++v+   E++eL r +N M+ +Lr+
  EEA20898.1 687 EITDAATDGDFTKLITVNASGEMDELKRKINKMVSNLRD 725
                 34455557*****************************96 PP

>> HATPase_c  Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0         6   3.1e+03       6      26 ..     620     640 ..     615     679 .. 0.75
   2 !  111.9   0.1   4.3e-35   2.2e-32       1     108 [.     856     971 ..     856     975 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 6
                 HHHHHHHHHHHHHHHHSTTTE CS
   HATPase_c   6 LrqiisnlvdNavkfatkage 26 
                 L+  i+n+vd ++kfat+ ++
  EEA20898.1 620 LKVTINNMVDRLAKFATELKR 640
                 677899999999999665443 PP

  == domain 2  score: 111.9 bits;  conditional E-value: 4.3e-35
                 EHHHHHHHHHHHHHHHHHHHHSTTTEEEEEEEEEE........TEEEEEEEESSSSSTTHHHTGTCSTTCH.HCSTCHTSTSSSHHHHHHHHHHHHTTT CS
   HATPase_c   1 gdekrLrqiisnlvdNavkfatkageieveikase........ddlvisveDnGiGipkedlkklfekfsq.ddstkrggggtGlGlsivkklvelmgG 90 
                 gd+ rLrqii nlv+Na+kf t+ ge++++i++se          +++sv+D+GiGi +++l+++f+ f+q d+st+r+ ggtGlGlsi+k+lv+lmgG
  EEA20898.1 856 GDPFRLRQIILNLVGNAIKF-TEHGEVKLTISKSEreqcardeYAFEFSVSDTGIGIEEDKLDLIFDTFQQaDGSTTRRFGGTGLGLSISKRLVNLMGG 953
                 6889****************.99*********8434456666699999*************************************************** PP

                 EEEEEEETTTEEEEEEEE CS
   HATPase_c  91 eiwvesepgrGttftftl 108
                 ++wv+se g+G+tf+ft 
  EEA20898.1 954 DVWVTSEYGHGSTFHFTC 971
                 ***************975 PP

>> Response_reg  Response regulator receiver domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.0   0.5   8.9e-28   4.6e-25       1     111 [.    1129    1243 ..    1129    1244 .. 0.96

  Alignments for each domain:
  == domain 1  score: 88.0 bits;  conditional E-value: 8.9e-28
                    EEEESSSHHHHHHHHHHHHHTTEEEEEEESSHHHHHHHHHHHHESEEEEESSCSSSEHHHHHHHHHHCT.....TTSEEEEEESSTSHHHHHHHH CS
  Response_reg    1 vlivdDdplvrellrqlleeegyeevaeaedgkealellkeekvdlillDinmpgmdGlellkeireed.....pelpviiltahseeedaveal 90  
                    +l+++D++++++l  ++le+ +   v+++ +g+eal+ +k++++d+il+D++mp m G+e++ +ire +     + +p+i+ltah+   d+++++
    EEA20898.1 1129 ILLAEDNEVNQKLAVKILEKCNH-GVTVVGNGQEALDAVKNRRFDIILMDVQMPIMGGFEATAKIREYErennlSRTPIIALTAHAMLGDREKCI 1222
                    89*****************9999.99***************************************99987667777******************* PP

                    HCTESEEEESSG-HHHHHHHH CS
  Response_reg   91 kagaddflsKpfdpeeLlkal 111 
                    +a +d++lsKp++++++++ +
    EEA20898.1 1223 QAQMDEYLSKPLKQNQMIQTI 1243
                    *****************9976 PP

>> HisKA  His Kinase A (phospho-acceptor) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       7.5   3.8e+03      49      63 ..     346     360 ..     303     362 .. 0.69
   2 !   58.5   0.1   9.5e-19   4.9e-16       2      66 ..     744     808 ..     743     809 .. 0.96
   3 ?   -1.7   0.0       5.9     3e+03      14      54 ..    1203    1243 ..    1203    1248 .. 0.50

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 7.5
                 HHHHHHHHHHHHHCC CS
       HisKA  49 rrldhlvedlLdlsr 63 
                 + ++ +v++l+++++
  EEA20898.1 346 QTINTMVDQLRTFAT 360
                 377788888887775 PP

  == domain 2  score: 58.5 bits;  conditional E-value: 9.5e-19
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHC..T-HSSCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH CS
       HisKA   2 lgrflagvaHELrtPLsailgnaeaLkregklteelkeyletiesearrldhlvedlLdlsriea 66 
                 +++fla+++HE+rtP+++i+g++++  ++++l +  +e+l+++++ a+ l+ +++d+Ld+s+iea
  EEA20898.1 744 KSEFLANMSHEIRTPMNGIIGMTQLTLDTDDLKPYPREMLNVVHNLANSLLTIIDDILDISKIEA 808
                 89***********************98888999******************************98 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 5.9
                  HHHHHHHHHHHHHHHC..........T-HSSCHHHHHHHHHHHHHHHHH CS
       HisKA   14 rtPLsailgnaeaLkre........gklteelkeyletiesearrldhl 54  
                  rtP+ a+ + a +  re        +        yl +  ++ + ++ +
  EEA20898.1 1203 RTPIIALTAHAMLGDREkciqaqmdE--------YLSKPLKQNQMIQTI 1243
                  67777776666666665564444441........444444444433333 PP

>> APG17  Autophagy protein Apg17
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.5   0.9   0.00022      0.11     110     284 ..     188     411 ..     131     423 .. 0.58
   2 !   13.7   0.0     5e-05     0.026     122     192 ..     423     495 ..     418     510 .. 0.85
   3 ?    4.8   0.0     0.024        13     124     196 ..     517     591 ..     510     601 .. 0.87
   4 !    9.9   0.3   0.00071      0.36     130     247 ..     615     800 ..     600     814 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00022
                 STGGGCS--TTTTHHHHHHHHH........................................HHHHHHHHHHHHTTHH..HHHHHHHHHHH......-- CS
       APG17 110 ktLlDFvdedsveelkealkes........................................idelqaaqkkldssllefdtdlrelkkel......sk 162
                 +tL   v +++v  l+++l++                                         i+ ++++ + + ++l+ f ++++ + +e+        
  EEA20898.1 188 RTLVK-VEHEDVGVLQRELRKHqqaneafqkalreiggiitqvangdlsmkvqihplemdpeIATFKRTINTMMDQLQVFGSEVSRVAREVgtegilG- 284
                 33333.33333333333332222333333333333366666666666666666666666666888888888888888888888888888886644331. PP

                 -----STCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH...................S-CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.... CS
       APG17 163 sksksessslipellkelesleeemAslLesLtnHfDqcvkAvkltegggal.rraaae..lseeereelleVlekDaaeledVvkelqerleem.... 254
                    ++++ + ++ + kel++  + mA+ L+  ++    +++Av + + +++  +ra++e    ++  + +++ l   a+e+  V +++ ++        
  EEA20898.1 285 ---GQAQITGVHGIWKELTENVNIMAKNLTDQVREIATVTTAVAHGDLSQKIeSRAHGEifELQQTINTMVDQLRTFATEVTRVARDVGTEGVLGgqaq 380
                 ...457888888888888888888888888888888888888888888777777777775533444577888888888888888877766543333323 PP

                 .HHHHHHHHHHHHHHHHHHHHHHHHHHHHH. CS
       APG17 255 .ekakkllsekkeeiekllsalkkaleelee 284
                  e ++  ++e + +++++ ++l+ +++++ +
  EEA20898.1 381 iEGVQGMWNELTVNVNAMANNLTTQVRDIAN 411
                 3555555555555555555555555555555 PP

  == domain 2  score: 13.7 bits;  conditional E-value: 5e-05
                 THHHHHHHHHHHHHHHHHHHHHTTHH..HHHHHHHHHHH.....-------STCCHHHHHHHHHHHHHHHHHHHHH CS
       APG17 122 eelkealkesidelqaaqkkldssllefdtdlrelkkel.....sksksksessslipellkelesleeemAslLe 192
                 ++++ + k +i+el+++ +++ ++l++f ++++++ ke+          ++++ + ++   k+l++  ++mA+ L+
  EEA20898.1 423 QKVQANCKGEIAELKNIINSMVDQLRQFAQEVTKIAKEVgtdgvL---GGQATVHDVEGTWKDLTENVNRMANNLT 495
                 6678888999*****************************885441...4568888999999999999999999886 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.024
                 HHHHHHHHHHHHHHHHHHHHTTHH..HHHHHHHHHHH..-------STCCHHHHHHHHHHHHHHHHHHHHHHHHH CS
       APG17 124 lkealkesidelqaaqkkldssllefdtdlrelkkel..sksksksessslipellkelesleeemAslLesLtn 196
                 +  +++ +i +l+++ +++ ++l++f  +++++ +e+  + +  ++++ + ++   k+l++  + mA+ L+s ++
  EEA20898.1 517 VTANVQGEILDLKNTINDMVDRLNKFAFEVSKVAREVgtDGTLGGQAKVDNVEGKWKDLTDNVNTMAQNLTSQVR 591
                 55677888999999***********************87333445699999*********************876 PP

  == domain 4  score: 9.9 bits;  conditional E-value: 0.00071
                 HHHHHHHHHHHHHHTTHH..HHHHHHHHHHH..-------STCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH...................... CS
       APG17 130 esidelqaaqkkldssllefdtdlrelkkel..sksksksessslipellkelesleeemAslLesLtnHfDqcvkAvkltegggalrraaae...... 220
                  +i  l+ + +++ ++l +f t+l+ + + +  + +  ++++ + i    ke ++  + mA+ L+s ++ f   + A   t+g+   + ++++      
  EEA20898.1 615 GEILTLKVTINNMVDRLAKFATELKRVARDVgvDGKMGGQANVEGIAGRWKEITEDVNTMAENLTSQVRAFGEITDA--ATDGDFT-KLITVNasgemd 710
                 456777788889999999*************9854566779***********************************9..4454432.445555556677 PP

                 ...........................................................S-CCH....HHHHHHHHHHHHHHHHHHHHHH CS
       APG17 221 ...........................................................lseee....reelleVlekDaaeledVvkel 247
                                                                            l+ ++     +e+l+V+++ a+ l  +++++
  EEA20898.1 711 elkrkinkmvsnlrdsiqrntaareaaeqanrtkseflanmsheirtpmngiigmtqltLDTDDlkpyPREMLNVVHNLANSLLTIIDDI 800
                 777777777777777777777777777777777777777777777777777777777664444444445677777777777777776666 PP

>> Syntaxin_2  Syntaxin-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.049        25       3      63 ..     261     324 ..     259     336 .. 0.86
   2 ?    5.1   0.0     0.057        29       4      72 ..     354     427 ..     337     442 .. 0.68
   3 !   10.2   0.0    0.0014      0.73       3      65 ..     445     510 ..     443     527 .. 0.87
   4 ?    6.7   0.0     0.018       9.4       5      62 ..     539     599 ..     535     619 .. 0.81
   5 ?    5.0   0.3      0.06        31      26      94 ..     655     732 ..     622     739 .. 0.65

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.049
  Syntaxin_2   3 snlqkinsnvstleklvkq...Lgtkkdteelreklhelieeinelikktnellkklsqldnss 63 
                 ++lq + s vs   + v +   Lg + + + ++   +el+e++n ++k+ +++++++++++   
  EEA20898.1 261 DQLQVFGSEVSRVAREVGTegiLGGQAQITGVHGIWKELTENVNIMAKNLTDQVREIATVTTAV 324
                 689999999999999999999999999999999999*********************9988765 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.057
  Syntaxin_2   4 nlqkinsnvstleklvkq...Lgtkkdteelreklhelieeinelikktnellkklsqldnsssds..qqklqk 72 
                 +l ++++ v+   + v +   Lg + + e ++   +el+ ++n ++++ + ++++++++++   +   +qk+q+
  EEA20898.1 354 QLRTFATEVTRVARDVGTegvLGGQAQIEGVQGMWNELTVNVNAMANNLTTQVRDIANVTKAVAKGdlTQKVQA 427
                 33444444444444444444444444577777888999999999999999999999999988866677777764 PP

  == domain 3  score: 10.2 bits;  conditional E-value: 0.0014
  Syntaxin_2   3 snlqkinsnvstleklvkq...Lgtkkdteelreklhelieeinelikktnellkklsqldnsssd 65 
                 ++l ++++ v+++ k v +   Lg +    ++    ++l+e++n+++++ + +++++++++    +
  EEA20898.1 445 DQLRQFAQEVTKIAKEVGTdgvLGGQATVHDVEGTWKDLTENVNRMANNLTTHVREIAEVTTAVAK 510
                 699***************99*************************************999877654 PP

  == domain 4  score: 6.7 bits;  conditional E-value: 0.018
  Syntaxin_2   5 lqkinsnvstleklvkq...Lgtkkdteelreklhelieeinelikktnellkklsqldns 62 
                 l k++  vs+  + v +   Lg +   +++  k ++l++++n+++++ +++++ +s +++ 
  EEA20898.1 539 LNKFAFEVSKVAREVGTdgtLGGQAKVDNVEGKWKDLTDNVNTMAQNLTSQVRGISDVTQA 599
                 66777777777777777777999999**************************999988765 PP

  == domain 5  score: 5.0 bits;  conditional E-value: 0.06
  Syntaxin_2  26 kdteelreklhelieeinelikktnellkklsqldnsssds........qqklqkekLkkdfkealqeFq.kiqrqya 94 
                  + e +  + +e++e++n+++++ +++++ + ++++   d         +   + + Lk+++++ ++++  +iqr+ a
  EEA20898.1 655 ANVEGIAGRWKEITEDVNTMAENLTSQVRAFGEITDAATDGdftklitvNASGEMDELKRKINKMVSNLRdSIQRNTA 732
                 446666777888999999999999999999999888887778866655533336666777777666666523444444 PP

>> DUF4279  Domain of unknown function (DUF4279)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0       5.5   2.8e+03      51      81 ..     251     281 ..     246     286 .. 0.85
   2 ?    1.7   0.0      0.55   2.8e+02      51      84 ..     343     376 ..     333     407 .. 0.83
   3 ?    6.0   0.0     0.026        13      50     109 ..     434     493 ..     423     507 .. 0.80
   4 ?    3.7   0.0      0.13        67      50      84 ..     526     560 ..     515     588 .. 0.83
   5 ?    3.7   0.0      0.14        70      50      79 ..     618     647 ..     608     658 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 5.5
     DUF4279  51 dleeqldklldrlepkaekikelakkyglei 81 
                 +++  ++++ d+l+ + +++ ++a++ g e 
  EEA20898.1 251 TFKRTINTMMDQLQVFGSEVSRVAREVGTEG 281
                 6788899**************9999887765 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.55
     DUF4279  51 dleeqldklldrlepkaekikelakkygleiylq 84 
                 +l+  +++++d+l  +a ++ ++a++ g e +l+
  EEA20898.1 343 ELQQTINTMVDQLRTFATEVTRVARDVGTEGVLG 376
                 68889********************999887765 PP

  == domain 3  score: 6.0 bits;  conditional E-value: 0.026
     DUF4279  50 ldleeqldklldrlepkaekikelakkygleiylqvviyiedgeqpelhldkevleflaa 109
                  +l++ +++++d+l ++a+++ ++ak+ g + +l+   +++d e++   l   v +++++
  EEA20898.1 434 AELKNIINSMVDQLRQFAQEVTKIAKEVGTDGVLGGQATVHDVEGTWKDLTENVNRMANN 493
                 578999*********************999998877666666665544666666666655 PP

  == domain 4  score: 3.7 bits;  conditional E-value: 0.13
     DUF4279  50 ldleeqldklldrlepkaekikelakkygleiylq 84 
                 ldl++ +++++drl+++a ++ ++a++ g + +l+
  EEA20898.1 526 LDLKNTINDMVDRLNKFAFEVSKVAREVGTDGTLG 560
                 7999**********************988887775 PP

  == domain 5  score: 3.7 bits;  conditional E-value: 0.14
     DUF4279  50 ldleeqldklldrlepkaekikelakkygl 79 
                 l+l+  ++ ++drl ++a ++k++a++ g+
  EEA20898.1 618 LTLKVTINNMVDRLAKFATELKRVARDVGV 647
                 678999*******************98766 PP

>> DUF948  Bacterial protein of unknown function (DUF948)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.2       3.8   1.9e+03      24      49 ..     140     165 ..     135     231 .. 0.69
   2 ?    7.1   2.0     0.012       6.4      40      79 ..     287     326 ..     243     338 .. 0.74
   3 ?    6.1   6.5     0.026        14      23      79 ..     354     418 ..     331     428 .. 0.80
   4 !    9.1   0.2     0.003       1.6      20      79 ..     627     694 ..     617     696 .. 0.75
   5 ?    0.2   0.1       1.8   9.4e+02      46      78 ..     706     738 ..     699     748 .. 0.59

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 3.8
      DUF948  24 lkktldeaaatieelekqvdpilkev 49 
                  ++tl+  a+t+++l+++v++  +e+
  EEA20898.1 140 RRRTLRGGAETLRSLQNHVEKQAHEI 165
                 56677777777777776666665554 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.012
      DUF948  40 kqvdpilkevedllakvnelledvneklekvdplteavad 79 
                  q++++    ++l+++vn +++++++++ ++ ++t+ava+
  EEA20898.1 287 AQITGVHGIWKELTENVNIMAKNLTDQVREIATVTTAVAH 326
                 6777777777899999999*****************9973 PP

  == domain 3  score: 6.1 bits;  conditional E-value: 0.026
      DUF948  23 klkktldeaaatieele........kqvdpilkevedllakvnelledvneklekvdplteavad 79 
                 +l+  ++e+++  ++++         q++++    ++l+ +vn+++++++ ++ ++ ++t+ava+
  EEA20898.1 354 QLRTFATEVTRVARDVGtegvlggqAQIEGVQGMWNELTVNVNAMANNLTTQVRDIANVTKAVAK 418
                 344444455555555559999999999************************************85 PP

  == domain 4  score: 9.1 bits;  conditional E-value: 0.003
      DUF948  20 vllklkktldeaaatieele........kqvdpilkevedllakvnelledvneklekvdplteavad 79 
                 ++ +l+k ++e+++  ++++         +v++i    +++++ vn+++e++++++ +  ++t+a+ d
  EEA20898.1 627 MVDRLAKFATELKRVARDVGvdgkmggqANVEGIAGRWKEITEDVNTMAENLTSQVRAFGEITDAATD 694
                 33344555555555555555999999989999999999999999999999999999999999999865 PP

  == domain 5  score: 0.2 bits;  conditional E-value: 1.8
      DUF948  46 lkevedllakvnelledvneklekvdplteava 78 
                 + e+++l +k+n++++++++ +++  +  ea++
  EEA20898.1 706 SGEMDELKRKINKMVSNLRDSIQRNTAAREAAE 738
                 455666666666666666665555555555544 PP

>> Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.2       1.3   6.9e+02      34      82 ..     250     309 ..     207     317 .. 0.60
   2 ?    2.2  10.2      0.32   1.7e+02      32     116 ..     341     410 ..     245     428 .. 0.55
   3 !   17.7   5.1   5.6e-06    0.0029       6     121 ..     424     545 ..     419     559 .. 0.80
   4 ?    3.5   1.3      0.13        67      56      83 ..     570     597 ..     562     646 .. 0.44
   5 ?    0.4   3.7       1.2     6e+02      50      82 ..     667     688 ..     620     805 .. 0.63

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 1.3
  Baculo_PEP_C  34 aqlatlldaietqLnalsedlksllaeldt...........rldtlltnLtdalnalqdt 82 
                   a  +++++++  qL+ + ++++++  e+ t            ++   ++Lt+ +n ++++
    EEA20898.1 250 ATFKRTINTMMDQLQVFGSEVSRVAREVGTegilggqaqitGVHGIWKELTENVNIMAKN 309
                   444555555555666666666666666555555555555554444444444444444433 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.32
  Baculo_PEP_C  32 ilaqlatlldaietqLnalsedlksllaeldt...........rldtlltnLtdalnalqdtlrneLtnlnsiltnLlssvtNinstLnnllqaln 116
                   i  +l+++++++  qL +++++++++  ++ t            ++ + ++Lt  +na++++l                         +  + +++
    EEA20898.1 341 I-FELQQTINTMVDQLRTFATEVTRVARDVGTegvlggqaqieGVQGMWNELTVNVNAMANNL-------------------------TTQVRDIA 410
                   2.2344444444444444444444444444444444444433333333333333333333222.........................22222222 PP

  == domain 3  score: 17.7 bits;  conditional E-value: 5.6e-06
  Baculo_PEP_C   6 qLnggggnqfldLtnvLnairlqnvqilaqlatlldai..etqL..nalsedlksllaeldtrldtlltnLtdalnalq..dtlrneLtnlnsiltn 96 
                   ++  +  ++  +L n++n++  q+ q + +++++ +++  +++L  +a  +d++   ++l+++++ +++nLt+ + +++  +t   + + + ++ +n
    EEA20898.1 424 KVQANCKGEIAELKNIINSMVDQLRQFAQEVTKIAKEVgtDGVLggQATVHDVEGTWKDLTENVNRMANNLTTHVREIAevTTAVAKGDLTRKVTAN 520
                   45667778899*********999999999999999988334567334667899**************************55444444455677778* PP

  Baculo_PEP_C  97 LlssvtNinstLnnllqalnnldlg 121
                    + ++  +++t+n ++  ln ++ +
    EEA20898.1 521 VQGEILDLKNTINDMVDRLNKFAFE 545
                   *******************998654 PP

  == domain 4  score: 3.5 bits;  conditional E-value: 0.13
  Baculo_PEP_C  56 sllaeldtrldtlltnLtdalnalqdtl 83 
                      ++l+++++t+++nLt+++  ++d  
    EEA20898.1 570 GKWKDLTDNVNTMAQNLTSQVRGISDVT 597
                   3344455555555555555555555221 PP

  == domain 5  score: 0.4 bits;  conditional E-value: 1.2
  Baculo_PEP_C  50 lsedlksllaeldtrldtlltnLtdalnalqdt 82 
                   ++ed++ + ++l++++            a+ + 
    EEA20898.1 667 ITEDVNTMAENLTSQVR-----------AFGEI 688
                   33333333333333222...........22211 PP

>> WXG100  Proteins of 100 residues with WXG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.1       9.1   4.7e+03      57      77 ..     209     229 ..     202     232 .. 0.52
   2 ?    1.7   0.0       0.6   3.1e+02       2      36 ..     238     272 ..     237     277 .. 0.79
   3 ?    6.5   0.2     0.019       9.8      15      79 ..     302     367 ..     296     370 .. 0.92
   4 !    8.1   0.7    0.0062       3.2      15      80 ..     394     460 ..     383     463 .. 0.94
   5 ?    3.5   0.0      0.17        87      50      83 ..     477     510 ..     469     512 .. 0.86
   6 ?    4.8   0.1     0.064        33      14      79 ..     577     643 ..     560     646 .. 0.90
   7 ?    3.1   0.7      0.22   1.1e+02      47      84 ..     703     740 ..     656     742 .. 0.71

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 9.1
                 HHHHHHHHHHHHHHHHHHHHH CS
      WXG100  57 kqaaqklvdaLeeisealkqa 77 
                 +qa + +++aL ei+  ++q+
  EEA20898.1 209 QQANEAFQKALREIGGIITQV 229
                 444445555555555444444 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.6
                 HCSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      WXG100   2 ikvdpeelrqaaarfqkqaeeledelqrlkaevda 36 
                 +++ p e++  +a+f+++ ++++d+lq   +ev+ 
  EEA20898.1 238 VQIHPLEMDPEIATFKRTINTMMDQLQVFGSEVSR 272
                 68888899999999999999999999877777665 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.019
                 HHHHHHHHHHHHHHHHHHHHHHC.GCGCTHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      WXG100  15 rfqkqaeeledelqrlkaevdal.qsgWsGaaadafqaefeewkqaaqklvdaLeeisealkqaan 79 
                 +++  a++l+d++++++    a+ +++ s +  ++ ++e+ e++q+++++vd+L + + +++++a+
  EEA20898.1 302 NVNIMAKNLTDQVREIATVTTAVaHGDLSQKIESRAHGEIFELQQTINTMVDQLRTFATEVTRVAR 367
                 566779999**************9************************************999986 PP

  == domain 4  score: 8.1 bits;  conditional E-value: 0.0062
                 HHHHHHHHHHHHHHHHHHHHHHC.GCGCTHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      WXG100  15 rfqkqaeeledelqrlkaevdal.qsgWsGaaadafqaefeewkqaaqklvdaLeeisealkqaana 80 
                 ++++ a++l+++++++++  +a+ +++   + +  +++e++e+k+ ++ +vd+L + +++++++a++
  EEA20898.1 394 NVNAMANNLTTQVRDIANVTKAVaKGDLTQKVQANCKGEIAELKNIINSMVDQLRQFAQEVTKIAKE 460
                 6888999*********************************************************986 PP

  == domain 5  score: 3.5 bits;  conditional E-value: 0.17
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      WXG100  50 qaefeewkqaaqklvdaLeeisealkqaanafed 83 
                 +++++ +++++++++++L+++ +++ ++++a+++
  EEA20898.1 477 EGTWKDLTENVNRMANNLTTHVREIAEVTTAVAK 510
                 678999***************9999999888776 PP

  == domain 6  score: 4.8 bits;  conditional E-value: 0.064
                 HHHHHHHHHHHHHHHHHHHHHHHC.GCGCTHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      WXG100  14 arfqkqaeeledelqrlkaevdal.qsgWsGaaadafqaefeewkqaaqklvdaLeeisealkqaan 79 
                  ++++ a++l+++++ +    +a+ +++ s +  +  q+e+  +k +++++vd L++ + +lk++a+
  EEA20898.1 577 DNVNTMAQNLTSQVRGISDVTQAIaKGDLSKKIEVHAQGEILTLKVTINNMVDRLAKFATELKRVAR 643
                 6788999999999999999999999999999999999999999999999999999999999999886 PP

  == domain 7  score: 3.1 bits;  conditional E-value: 0.22
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      WXG100  47 dafqaefeewkqaaqklvdaLeeisealkqaanafeda 84 
                 +   +e++e+k++++k+v +L +  +  ++a +a e+a
  EEA20898.1 703 VNASGEMDELKRKINKMVSNLRDSIQRNTAAREAAEQA 740
                 56678999999999999999998888777777766665 PP

>> DUF1843  Domain of unknown function (DUF1843)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.54   2.8e+02       6      43 ..     319     355 ..     318     362 .. 0.64
   2 ?    2.0   0.1      0.59     3e+02       8      43 ..     413     447 ..     410     457 .. 0.62
   3 ?    0.6   0.0       1.6   8.1e+02       8      43 ..     505     539 ..     502     549 .. 0.70
   4 ?    5.4   0.0     0.052        27       8      27 ..     597     616 ..     595     632 .. 0.85
   5 ?    1.2   0.0         1   5.3e+02       7      29 ..     688     710 ..     686     729 .. 0.75

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.54
     DUF1843   6 aiqqAiasGDLakMKalaaqaeqqLaeygdiasaleqL 43 
                 + + A+a GDL++  +  a  e   + ++ i ++++qL
  EEA20898.1 319 TVTTAVAHGDLSQKIESRAHGEI-FELQQTINTMVDQL 355
                 6789*******984333333333.25555666666666 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.59
     DUF1843   8 qqAiasGDLakMKalaaqaeqqLaeygd.iasaleqL 43 
                 ++A+a GDL +  ++ a+ +   ae ++ i s+++qL
  EEA20898.1 413 TKAVAKGDLTQ--KVQANCKGEIAELKNiINSMVDQL 447
                 68999999987..444444444555555235556655 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 1.6
     DUF1843   8 qqAiasGDLakMKalaaqaeqqLaeygdiasaleqL 43 
                 + A+a GDL + K +a    + L+ +  i  +++ L
  EEA20898.1 505 TTAVAKGDLTR-KVTANVQGEILDLKNTINDMVDRL 539
                 689******87.666666666666666666666655 PP

  == domain 4  score: 5.4 bits;  conditional E-value: 0.052
     DUF1843   8 qqAiasGDLakMKalaaqae 27 
                 +qAia GDL+k  +++aq e
  EEA20898.1 597 TQAIAKGDLSKKIEVHAQGE 616
                 79********9888888876 PP

  == domain 5  score: 1.2 bits;  conditional E-value: 1
     DUF1843   7 iqqAiasGDLakMKalaaqaeqq 29 
                 i++A+ +GD  k+ ++ a  e  
  EEA20898.1 688 ITDAATDGDFTKLITVNASGEMD 710
                 89*********999998887765 PP

>> DUF3829  Protein of unknown function (DUF3829)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.0     0.018       9.1     215     278 ..     292     355 ..     247     357 .. 0.86
   2 ?    5.0   0.3     0.028        14     215     278 ..     384     447 ..     371     449 .. 0.88
   3 ?   11.3   0.6   0.00034      0.17     186     280 .]     431     541 ..     423     541 .. 0.82
   4 ?    0.7   0.1      0.59     3e+02     215     277 ..     568     630 ..     558     633 .. 0.80
   5 ?    0.3   0.2      0.75   3.9e+02     188     277 ..     631     722 ..     604     725 .. 0.64
   6 ?    0.3   0.3      0.75   3.9e+02     214     238 ..     694     728 ..     651     755 .. 0.56

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.018
     DUF3829 215 kkpalesfkssakeflaaarkiirrirdkepysdsdkellksadsvegspeallrkynelidey 278
                  +  + +++++++ + +++++ +r+i++ +++  + +  +k+ +++ g   +l++ +n ++d+ 
  EEA20898.1 292 VHGIWKELTENVNIMAKNLTDQVREIATVTTAVAHGDLSQKIESRAHGEIFELQQTINTMVDQL 355
                 67899***********************9999888876666999*****************986 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.028
     DUF3829 215 kkpalesfkssakeflaaarkiirrirdkepysdsdkellksadsvegspeallrkynelidey 278
                  + ++++++ +++++  ++++ +r+i++ + +  + +  +k + + +g  ++l + +n+++d+ 
  EEA20898.1 384 VQGMWNELTVNVNAMANNLTTQVRDIANVTKAVAKGDLTQKVQANCKGEIAELKNIINSMVDQL 447
                 6789************************999988888777799******************986 PP

  == domain 3  score: 11.3 bits;  conditional E-value: 0.00034
     DUF3829 186 ldlaklkkklddlekaleklekaskeekr................kkpalesfkssakeflaaarkiirrirdkepysdsdkellksadsvegspeall 268
                  ++a+lk  ++ +  +l+++ +  ++ ++                 +  + +++++++ +  ++++ +r+i++ +++  + +  +k   +v+g   +l 
  EEA20898.1 431 GEIAELKNIINSMVDQLRQFAQEVTKIAKevgtdgvlggqatvhdVEGTWKDLTENVNRMANNLTTHVREIAEVTTAVAKGDLTRKVTANVQGEILDLK 529
                 667777777777777777775554444444777888888888999999*************************99999999877779999********* PP

     DUF3829 269 rkynelideyNs 280
                 + +n+++d+ N+
  EEA20898.1 530 NTINDMVDRLNK 541
                 *********995 PP

  == domain 4  score: 0.7 bits;  conditional E-value: 0.59
     DUF3829 215 kkpalesfkssakeflaaarkiirrirdkepysdsdkellksadsvegspeallrkynelide 277
                  + ++ +++++++++ +++++ +r i d + +  + +  +k+   ++g    l   +n+++d+
  EEA20898.1 568 VEGKWKDLTDNVNTMAQNLTSQVRGISDVTQAIAKGDLSKKIEVHAQGEILTLKVTINNMVDR 630
                 67899**********************988776666555558888888888888899999986 PP

  == domain 5  score: 0.3 bits;  conditional E-value: 0.75
     DUF3829 188 laklkkklddlekaleklekaskeekr...kkpalesfkssakeflaaarkiirrird.kepysdsdkellksadsvegspeallrkynelide 277
                 lak+ ++l+ +++++   ++++  +++       + +++++++++ +++++ +r   +  ++++d+d ++l +  +++g   +l rk+n++++ 
  EEA20898.1 631 LAKFATELKRVARDV-GVDGKMGGQANvegIAGRWKEITEDVNTMAENLTSQVRAFGEiTDAATDGDFTKL-ITVNASGEMDELKRKINKMVSN 722
                 555555555555553.3455555555555534467777788888777777777754331233344444444.6667899999999999999986 PP

  == domain 6  score: 0.3 bits;  conditional E-value: 0.75
     DUF3829 214 r..........kkpalesfkssakeflaaarkiir 238
                 +           + +++++k++++++++++r+ i+
  EEA20898.1 694 DgdftklitvnASGEMDELKRKINKMVSNLRDSIQ 728
                 22233333333445566666666666666666666 PP

>> Gp-FAR-1  Nematode fatty acid retinoid binding protein (Gp-FAR-1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       7.9   4.1e+03      63     109 ..     251     297 ..     249     326 .. 0.71
   2 ?    3.9   0.0      0.12        61      50     109 ..     330     389 ..     291     408 .. 0.75
   3 ?    3.5   0.1      0.16        83      60     117 ..     432     489 ..     418     510 .. 0.79
   4 ?   -0.5   0.0       2.9   1.5e+03      53     113 ..     483     537 ..     479     555 .. 0.69
   5 ?    4.4   0.1     0.088        45      51     117 ..     573     633 ..     565     645 .. 0.74

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 7.9
    Gp-FAR-1  63 klkekvdkLspeakeFvkkliakgrkleaqvlagekpdlselkkvak 109
                 ++k+ ++++ ++ + F  +++  +r++ ++ + g + + + +  + k
  EEA20898.1 251 TFKRTINTMMDQLQVFGSEVSRVAREVGTEGILGGQAQITGVHGIWK 297
                 67888889999999999999988888888877777766555544444 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.12
    Gp-FAR-1  50 spaLyekaeklqaklkekvdkLspeakeFvkkliakgrkleaqvlagekpdlselkkvak 109
                 s ++ ++a     +l++ ++++ ++ ++F++++   +r + ++ + g + + + ++ + +
  EEA20898.1 330 SQKIESRAHGEIFELQQTINTMVDQLRTFATEVTRVARDVGTEGVLGGQAQIEGVQGMWN 389
                 66777888888899********************99999998888887777666655554 PP

  == domain 3  score: 3.5 bits;  conditional E-value: 0.16
    Gp-FAR-1  60 lqaklkekvdkLspeakeFvkkliakgrkleaqvlagekpdlselkkvaktifnkyks 117
                   a+lk+ ++++ ++ ++F++++ + ++++ ++ + g + + +++  + k+  ++ + 
  EEA20898.1 432 EIAELKNIINSMVDQLRQFAQEVTKIAKEVGTDGVLGGQATVHDVEGTWKDLTENVNR 489
                 55789999**********************9999999999988877666666655554 PP

  == domain 4  score: -0.5 bits;  conditional E-value: 2.9
    Gp-FAR-1  53 LyekaeklqaklkekvdkLspeakeFvkkliakgrkleaqvlagekpdlselkkvaktifn 113
                 L e+++++ ++l++ v ++ + + + +k+  +  rk+ a+ ++ge +d   lk+++++++ 
  EEA20898.1 483 LTENVNRMANNLTTHVREIAEVTTAVAKG--DLTRKVTAN-VQGEILD---LKNTINDMVD 537
                 77788888888888888888888877777..777777777.5666666...5555444444 PP

  == domain 5  score: 4.4 bits;  conditional E-value: 0.088
    Gp-FAR-1  51 paLyekaeklqaklkekvdkLspeakeFvkkliakgrkleaqvlagekpdlselkkvaktifnkyks 117
                   L  +++++ ++l+ +v ++s+ +++ +k+ ++k  +++aq   ge ++   lk+++++++    +
  EEA20898.1 573 KDLTDNVNTMAQNLTSQVRGISDVTQAIAKGDLSKKIEVHAQ---GEILT---LKVTINNMVDRLAK 633
                 578999********************9999966555555555...44444...66666666655555 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.1       2.9   1.5e+03     101     119 ..     148     166 ..     138     178 .. 0.73
   2 ?    7.7   0.3    0.0072       3.7      34     114 ..     195     273 ..     174     278 .. 0.85
   3 ?    2.3   0.1      0.33   1.7e+02      51     108 ..     304     359 ..     289     369 .. 0.63
   4 ?    9.8   0.7    0.0017      0.87      49     116 ..     394     459 ..     379     463 .. 0.84
   5 ?    8.0   0.2    0.0058       2.9      48     106 ..     485     541 ..     470     553 .. 0.82
   6 ?    0.6   0.4       1.2     6e+02      49     106 ..     578     633 ..     562     645 .. 0.50
   7 ?    2.5   0.2       0.3   1.5e+02      24      66 ..     707     749 ..     702     798 .. 0.77

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 2.9
                 HHHHHHHHHHHHHHHHHHH CS
   Fib_alpha 101 esnirvLqnvlesneqkiq 119
                  +++r Lqn +e++ ++i+
  EEA20898.1 148 AETLRSLQNHVEKQAHEIS 166
                 5789999999999999986 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0072
                 CHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHH CS
   Fib_alpha  34 kkdlekleneleeisnstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvLqnvlesn 114
                 ++d+  l++el+++++ ++  ++  +ei  ++++  + +   +  ++    e++ ei+++k+ti++ + +++v  + +++ 
  EEA20898.1 195 HEDVGVLQRELRKHQQANEAFQKALREIGGIITQVANGDL--SMKVQIHPLEMDPEIATFKRTINTMMDQLQVFGSEVSRV 273
                 467888999*******************999987766665..78888899999999***************9987777665 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.33
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHH CS
   Fib_alpha  51 tkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvLq 108
                 +  a++l+ +++++ + + + ++    + +k++++   ei +l++ti++ + ++r   
  EEA20898.1 304 NIMAKNLTDQVREIATVTTAVAH--GDLSQKIESRAHGEIFELQQTINTMVDQLRTFA 359
                 33444555555555544444444..577777777777788888888888888877654 PP

  == domain 4  score: 9.8 bits;  conditional E-value: 0.0017
                 CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHH CS
   Fib_alpha  49 nstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvLqnvlesneq 116
                 n +  a++l+++++d+ + +++ +k    +++k++ +++ ei++lk+ i++ + ++r+  + + +  +
  EEA20898.1 394 NVNAMANNLTTQVRDIANVTKAVAK--GDLTQKVQANCKGEIAELKNIINSMVDQLRQFAQEVTKIAK 459
                 5667789999999999999999998..699**********************9999998887777665 PP

  == domain 5  score: 8.0 bits;  conditional E-value: 0.0058
                 CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHH CS
   Fib_alpha  48 snstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirv 106
                 +n ++ a++l+++++++ + + + +k    +++k++ +++ eil+lk+ti++ + ++++
  EEA20898.1 485 ENVNRMANNLTTHVREIAEVTTAVAK--GDLTRKVTANVQGEILDLKNTINDMVDRLNK 541
                 56778899999999999999999998..69*********************99988875 PP

  == domain 6  score: 0.6 bits;  conditional E-value: 1.2
                 CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHH CS
   Fib_alpha  49 nstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirv 106
                 n ++ a++l+++++ +   +q+ +k    + kk++ + + eil+lk ti++ + ++ +
  EEA20898.1 578 NVNTMAQNLTSQVRGISDVTQAIAK--GDLSKKIEVHAQGEILTLKVTINNMVDRLAK 633
                 2333344444444444444444444..3555555555556666666666666665554 PP

  == domain 7  score: 2.5 bits;  conditional E-value: 0.3
                 HCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH CS
   Fib_alpha  24 dlllkyekdvkkdlekleneleeisnstkeaeelvkeikdslr 66 
                 + +++ +++++k +++l++++++++   + ae+  ++ ++ l+
  EEA20898.1 707 GEMDELKRKINKMVSNLRDSIQRNTAAREAAEQANRTKSEFLA 749
                 5688888888888888888888888877777776655555554 PP

>> DUF4795  Domain of unknown function (DUF4795)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   2.3      0.45   2.3e+02      86     147 ..     245     357 ..     146     372 .. 0.66
   2 ?    7.2   0.3    0.0067       3.4      86     156 ..     384     458 ..     367     476 .. 0.84
   3 ?    4.7   1.0     0.038        20      85     147 ..     433     541 ..     413     555 .. 0.64
   4 ?    8.9   6.9    0.0021       1.1      20     170 ..     562     748 ..     470     753 .. 0.78

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.45
     DUF4795  86 fDeakkeLekmleellekle..........................eqeealkkaldtLq......................eelkekld...rlelep 133
                 +D  ++ +++ ++ ++++l+                          ++   +k++ ++++                       +l +k++   + e+ +
  EEA20898.1 245 MDPEIATFKRTINTMMDQLQvfgsevsrvarevgtegilggqaqitGVHGIWKELTENVNimaknltdqvreiatvttavahGDLSQKIEsraHGEIFE 343
                 666666666666666666656666666666666666666666666666666666666666777777777777777777777778888888877788888 PP

     DUF4795 134 Lkeqleerlkelqk 147
                 L++ ++  +++l++
  EEA20898.1 344 LQQTINTMVDQLRT 357
                 88888877777775 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0067
     DUF4795  86 fDeakkeLekmleellekleeqeealkkaldtLq.eelkekld...rlelepLkeqleerlkelqkelqeameke 156
                 ++ + +eL+ +++ + + l+ q +++  + + +   +l++k+    + e+ +Lk+ +++ +++l++  qe ++  
  EEA20898.1 384 VQGMWNELTVNVNAMANNLTTQVRDIANVTKAVAkGDLTQKVQancKGEIAELKNIINSMVDQLRQFAQEVTKIA 458
                 6778888999999999999999999999999998679***************************97777654443 PP

  == domain 3  score: 4.7 bits;  conditional E-value: 0.038
     DUF4795  85 q......fDeakkeLekmleellek...............leeqeealkkaldtLq......................eelkekld...rlelepLkeq 137
                        + +++++L++ ++e+ +                ++ +e  +k + ++++                       +l+ k+    + e+ +Lk+ 
  EEA20898.1 433 IaelkniINSMVDQLRQFAQEVTKIakevgtdgvlggqatVHDVEGTWKDLTENVNrmannltthvreiaevttavakGDLTRKVTanvQGEILDLKNT 531
                 144444567777777777777777744555555555555555888888888888887777777777777666666666666666667777777777777 PP

     DUF4795 138 leerlkelqk 147
                 +++ ++ l+k
  EEA20898.1 532 INDMVDRLNK 541
                 7777776664 PP

  == domain 4  score: 8.9 bits;  conditional E-value: 0.0021
     DUF4795  20 qeelekleekvkelekrledkekklealkkqieelekvkadkeeveeelaekadkeaLatkvsrdqfDeakkeLekml...................ee 99 
                 q++++++e+k k+l ++ ++  ++l +    i++  ++ a+  ++++++++ a  e L  kv  +++  +++++   l                   e 
  EEA20898.1 562 QAKVDNVEGKWKDLTDNVNTMAQNLTSQVRGISDVTQAIAK-GDLSKKIEVHAQGEILTLKVTINNMVDRLAKFATELkrvardvgvdgkmggqanvE- 658
                 67788899999999999999999999999999999888776.889999**************666644444444444422223334443333333333. PP

     DUF4795 100 llekleeqeealkkaldtLq.........................eelkekldrlelepLkeqleerlkelqkelqeamekedkedeaaglrkkLl 170
                       +   ++k++ ++++                         ++l + +   e+++Lk ++++ + +l++ +q  +++++ +++a  ++ + l
  EEA20898.1 659 ------GIAGRWKEITEDVNtmaenltsqvrafgeitdaatdgdfTKLITVNASGEMDELKRKINKMVSNLRDSIQRNTAAREAAEQANRTKSEFL 748
                 ......444455555555554444444888888877777777555555555559**********************98888877777877777666 PP

>> NOD  NOTCH protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.0     0.012       6.2       3      31 ..     228     256 ..     227     260 .. 0.86
   2 ?    3.9   0.0     0.077        40      21      38 ..     741     758 ..     736     760 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.012
         NOD   3 klaeGsLvlvVlidpeellnnskeFLrel 31 
                 ++a+G+L++ V+i+p e+  + ++F r +
  EEA20898.1 228 QVANGDLSMKVQIHPLEMDPEIATFKRTI 256
                 689***************99998886665 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.077
         NOD  21 lnnskeFLrelsalLrtn 38 
                  ++++eFL ++s+ +rt 
  EEA20898.1 741 NRTKSEFLANMSHEIRTP 758
                 578899**********95 PP

>> IcmF_C  Type VI secretion protein IcmF C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.1   0.00055      0.28      97     147 ..     209     257 ..     185     264 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00055
      IcmF_C  97 lglspaflkqfqraarirdalfa.gggepsvefeirplplsagvtelkleid 147
                  + ++af k++++   i  ++ +  +g++s++++i pl+++++++++k +i+
  EEA20898.1 209 QQANEAFQKALRE---IGGIITQvANGDLSMKVQIHPLEMDPEIATFKRTIN 257
                 3344444444444...5555566778*********************98876 PP

>> PA-IL  PA-IL-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.3      0.16        84      39      99 ..     379     438 ..     368     458 .. 0.77
   2 ?    8.4   0.1    0.0042       2.1      61     102 ..     493     533 ..     469     551 .. 0.82

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.16
                 STTBECECCCCSTTSS.S-TTTTCTCEEEEETTCEEEETTCEEEEEE-STTSBEEEEEEE- CS
       PA-IL  39 dqkegaagdrevpdqglipqdasiaalvakiankktiivntvlfktvapnnvdGelillyn 99 
                  q eg +g  +     + +    +++ v  ian   +++ + l + v   n +Ge+  l n
  EEA20898.1 379 AQIEGVQGMWNELTVNVNAMANNLTTQVRDIANVTKAVAKGDLTQKVQ-ANCKGEIAELKN 438
                 555555555444444455666778999********************9.899***987766 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0042
                 TCTCEEEEETTCEEEETTCEEEEEE-STTSBEEEEEEE---T CS
       PA-IL  61 siaalvakiankktiivntvlfktvapnnvdGelillyndvp 102
                  +++ v  ia+  t+++ + l + v+  nv+Ge++ l n + 
  EEA20898.1 493 NLTTHVREIAEVTTAVAKGDLTRKVT-ANVQGEILDLKNTIN 533
                 5788999******************9.99*****98888764 PP

>> CMD  Carboxymuconolactone decarboxylase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.0     0.025        13      15      41 ..     306     330 ..     294     346 .. 0.79
   2 ?    1.7   0.0      0.53   2.7e+02       7      39 ..     480     512 ..     475     517 .. 0.78
   3 ?   -1.0   0.0       3.8   1.9e+03      27      69 ..    1205    1248 ..    1186    1252 .. 0.74

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.025
                 CCGSSTS-HHHHHHHHHHHHHHTT-HH CS
         CMD  15 lareggLdpkereLialavsaangcey 41 
                 +a ++ L+ + re++++++++a+g   
  EEA20898.1 306 MA-KN-LTDQVREIATVTTAVAHGDLS 330
                 43.55.*****************9765 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.53
                 HHHHHHHHCC.GSSTS-HHHHHHHHHHHHHHTT- CS
         CMD   7 ltalrealla.reggLdpkereLialavsaangc 39 
                 + +l e++     ++L+   re++ +++++a g 
  EEA20898.1 480 WKDLTENVNRmA-NNLTTHVREIAEVTTAVAKGD 512
                 666666666644.56****************986 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 3.8
                  HHHHHHHHHHTT.-HHHHHHHHHHHHHTT--HHHHHHHHHHHHH CS
         CMD   27 eLialavsaang.ceyCvdaHtraAleaGvteeeiaevlaqaaa 69  
                   +ial++ a++g +e C++a + + l + + +++  +++   a 
  EEA20898.1 1205 PIIALTAHAMLGdREKCIQAQMDEYLSKPLKQNQMIQTILKCAT 1248
                  47999999999989999999999988888888888877776665 PP

>> DUF2457  Protein of unknown function (DUF2457)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6  17.3   0.00043      0.22      57      91 ..      83     132 ..      58     143 .. 0.51

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00043
     DUF2457  57 e...............eddeedeeddddddddedddedddeedededdds 91 
                                 +dd++d+ ddddd+dd+d  eddd++d+++dd++
  EEA20898.1  83 YkrprrsrklkrkyddDDDDDDTGDDDDDEDDSDGSEDDDDDDNEDDDHA 132
                 34455555555555324444444444444455555555555554444333 PP

>> CENP-F_leu_zip  Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.1      0.67   3.5e+02      82     108 ..      55      81 ..      35      93 .. 0.87
   2 ?   -0.1   0.0       1.7   8.8e+02      53      81 ..     248     276 ..     244     278 .. 0.88
   3 ?    2.6   0.1      0.25   1.3e+02      50      78 ..     337     365 ..     297     370 .. 0.86
   4 ?   10.0   0.1    0.0013      0.68      53     123 ..     387     460 ..     378     465 .. 0.79
   5 ?    3.4   0.0      0.14        74      57     112 ..     483     541 ..     472     555 .. 0.53
   6 ?    1.9   0.1      0.39     2e+02      50      78 ..     613     641 ..     562     645 .. 0.68
   7 ?    6.1   0.2     0.021        11      18      66 ..     708     757 ..     704     796 .. 0.79

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.67
  CENP-F_leu_zip  82 keeLekelqkkqervseLeslnsslen 108
                     k+ L+ el+   +rv+eLe+  +s  n
      EEA20898.1  55 KKALTTELECLIRRVHELETELVSHPN 81 
                     889999999999999999998887665 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 1.7
  CENP-F_leu_zip  53 evetlkeeieelaeelreleldLvalrse 81 
                     e+ t+k  i+++  +l+ + ++++ + +e
      EEA20898.1 248 EIATFKRTINTMMDQLQVFGSEVSRVARE 276
                     78999**************9999988765 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.25
  CENP-F_leu_zip  50 skaevetlkeeieelaeelreleldLval 78 
                     +  e+ +l++ i+++  +lr + ++++ +
      EEA20898.1 337 AHGEIFELQQTINTMVDQLRTFATEVTRV 365
                     4569999**************99998876 PP

  == domain 4  score: 10.0 bits;  conditional E-value: 0.0013
  CENP-F_leu_zip  53 evetlkeeieelaeelreleldLvalrs..ekeeLekelqkk.qervseLeslnsslenlleekEqekvqmkee 123
                       ++l  +++ +a++l+    d++++++   k +L++++q + + ++ eL+++  s+  +l++  qe  ++ +e
      EEA20898.1 387 MWNELTVNVNAMANNLTTQVRDIANVTKavAKGDLTQKVQANcKGEIAELKNIINSMVDQLRQFAQEVTKIAKE 460
                     55678888999999999999999999953369999999997548899999999999999999988888777766 PP

  == domain 5  score: 3.4 bits;  conditional E-value: 0.14
  CENP-F_leu_zip  57 lkeeieelaeelreleldLvalr..sekeeLekelq.kkqervseLeslnsslenllee 112
                     l e+++++a++l+    ++++++    k +L++++  + q ++ +L+++  ++   l++
      EEA20898.1 483 LTENVNRMANNLTTHVREIAEVTtaVAKGDLTRKVTaNVQGEILDLKNTINDMVDRLNK 541
                     55555555555555555555554223455555555413455565555555555444433 PP

  == domain 6  score: 1.9 bits;  conditional E-value: 0.39
  CENP-F_leu_zip  50 skaevetlkeeieelaeelreleldLval 78 
                     ++ e+ tlk  i+++  +l ++ ++L+ +
      EEA20898.1 613 AQGEILTLKVTINNMVDRLAKFATELKRV 641
                     45678889999999999999999998876 PP

  == domain 7  score: 6.1 bits;  conditional E-value: 0.021
  CENP-F_leu_zip  18 kadsLkdkvenLerelemseenqekvileaEtskaevet.lkeeieelae 66 
                     + d Lk k++++ ++l +s + ++++   aE++  + ++ l ++ +e+++
      EEA20898.1 708 EMDELKRKINKMVSNLRDSIQRNTAAREAAEQANRTKSEfLANMSHEIRT 757
                     6799*****************99999999999877665525555555555 PP

>> GLE1  GLE1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.0     0.032        17      25      98 ..     250     325 ..     236     340 .. 0.78
   2 ?    3.8   0.1     0.054        27      18      95 ..     335     414 ..     327     418 .. 0.71
   3 ?    4.5   0.8     0.034        17       9      53 ..     420     462 ..     413     528 .. 0.79
   4 ?   -2.1   0.0       3.5   1.8e+03       5      57 ..     489     544 ..     485     601 .. 0.60
   5 ?   -1.7   0.1       2.6   1.3e+03      24      44 ..     709     729 ..     704     757 .. 0.69

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.032
        GLE1  25 gdlkrkInpkvgQltnsseqlkkitkel..kellesgkpvkvadk.pelaykyllnflAkalvsqaetevsakpeaA 98 
                  + kr In+ + Ql+   ++++++++e+  + +l  + +++ +    ++ ++  +n++Ak+l +q+ + ++++++ A
  EEA20898.1 250 ATFKRTINTMMDQLQVFGSEVSRVAREVgtEGILGGQAQITGVHGiWKE-LTENVNIMAKNLTDQVREIATVTTAVA 325
                 5789***********************9445688555555444335444.58889************9999966555 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.054
        GLE1  18 kelkkllgdlkrkInpkvgQltnsseqlkkitkel..kellesgkpvkvadk..pelaykyllnflAkalvsqaetevsakp 95 
                 + +   +++l++ In+ v Ql++ +++++++++++  + +l  + +++ ++   +e  ++  +n +A++l  q+   + +++
  EEA20898.1 335 SRAHGEIFELQQTINTMVDQLRTFATEVTRVARDVgtEGVLGGQAQIEGVQGmwNE--LTVNVNAMANNLTTQVRDIANVTK 414
                 56677899************************998334566455554444445444..478888888888888776666555 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.034
        GLE1   9 nlleqvkedkelkkllgdlkrkInpkvgQltnsseqlkkitkelk 53 
                 +l ++v  +++ k  + +lk  In  v Ql++ +++++ki+ke+ 
  EEA20898.1 420 DLTQKV--QANCKGEIAELKNIINSMVDQLRQFAQEVTKIAKEVG 462
                 566644..6779*****************************9984 PP

  == domain 4  score: -2.1 bits;  conditional E-value: 3.5
        GLE1   5 qikknlleqvke..dkelkkllgdlkrkInpkv.gQltnsseqlkkitkelkelle 57 
                  + +nl + v e  + ++    gdl+rk++ +v g +   ++ +++++++l+++  
  EEA20898.1 489 RMANNLTTHVREiaEVTTAVAKGDLTRKVTANVqGEILDLKNTINDMVDRLNKFAF 544
                 55666666666655555666677788888877756777777888888888877763 PP

  == domain 5  score: -1.7 bits;  conditional E-value: 2.6
        GLE1  24 lgdlkrkInpkvgQltnsseq 44 
                 + +lkrkIn+ v+ l+ s + 
  EEA20898.1 709 MDELKRKINKMVSNLRDSIQR 729
                 567788888888877777633 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4  16.4   0.00025      0.13     640     677 ..      95     132 ..      75     184 .. 0.59
   2 ?   -3.7   0.1       4.3   2.2e+03     358     384 ..     715     742 ..     681     757 .. 0.53

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00025
  DNA_pol_phi 640 dededeeddeeeeeeddeededseedddeeesdedeed 677
                  + d+d++dd+  +++dde+d+d +eddd++++++d+  
   EEA20898.1  95 KYDDDDDDDDTGDDDDDEDDSDGSEDDDDDDNEDDDHA 132
                  33444444444444444444444433333333333332 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 4.3
  DNA_pol_phi 358 glkklvdllkslilssnee.sdekeaes 384
                  +++k+v +l++ i++++   ++ ++a++
   EEA20898.1 715 KINKMVSNLRDSIQRNTAArEAAEQANR 742
                  3445555555555552222334444444 PP

>> DUF1759  Protein of unknown function (DUF1759)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0     0.051        26      68     113 ..     328     373 ..     309     381 .. 0.87
   2 ?    2.3   0.1      0.27   1.4e+02      69     110 ..     421     462 ..     409     476 .. 0.85
   3 ?    1.2   0.0      0.61   3.1e+02      68     111 ..     512     555 ..     502     566 .. 0.87
   4 ?   -2.4   0.0       7.7   3.9e+03      70     110 ..     606     646 ..     577     654 .. 0.80

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.051
     DUF1759  68 dnkrkiirellnelmklpslkeedasqlrrivdavneivralealg 113
                 d ++ki +  + e+ +l+++ +  ++qlr++  +v ++ r + + g
  EEA20898.1 328 DLSQKIESRAHGEIFELQQTINTMVDQLRTFATEVTRVARDVGTEG 373
                 6678999999****************************99876655 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.27
     DUF1759  69 nkrkiirellnelmklpslkeedasqlrrivdavneivrale 110
                  ++k+ ++   e+ +l+++ ++ ++qlr++ ++v +i + + 
  EEA20898.1 421 LTQKVQANCKGEIAELKNIINSMVDQLRQFAQEVTKIAKEVG 462
                 56788888889999*****9*************999988765 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.61
     DUF1759  68 dnkrkiirellnelmklpslkeedasqlrrivdavneivralea 111
                 d +rk+ ++   e+ +l+++ ++ ++ l+++  +v ++ r + +
  EEA20898.1 512 DLTRKVTANVQGEILDLKNTINDMVDRLNKFAFEVSKVAREVGT 555
                 66899999999*********************999999998765 PP

  == domain 4  score: -2.4 bits;  conditional E-value: 7.7
     DUF1759  70 krkiirellnelmklpslkeedasqlrrivdavneivrale 110
                 ++ki  +   e+  l+ + ++ ++ l+++  ++ ++ r + 
  EEA20898.1 606 SKKIEVHAQGEILTLKVTINNMVDRLAKFATELKRVARDVG 646
                 66777777778888888888889999999999988888765 PP

>> Fez1  Fez1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   3.4     0.033        17      10     140 ..     431     582 ..     417     755 .. 0.73

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.033
        Fez1  10 GEislLKq.......QLkdsqaevtqklsei.....valkaqlrelrakleekeeeikeleesleektlelevcenelqrkkseaellrekvekleeel 96 
                 GEi+ LK+       QL++  +evt+ ++e+     +  +a++++++ + ++  e+++++ ++l+++ +e+ ++        ++ +l+r+ + +++ e+
  EEA20898.1 431 GEIAELKNiinsmvdQLRQFAQEVTKIAKEVgtdgvLGGQATVHDVEGTWKDLTENVNRMANNLTTHVREIAEVTTA----VAKGDLTRKVTANVQGEI 525
                 77777774444444489999999998888853333266677788888888888888888888888877776555444....445567777777788888 PP

        Fez1  97 kelreelselsleeeeaalesdeakaqrqe...............aeeleelkreverl 140
                  +l+++++++  + ++ a e ++  + r+                + + ++l+ +v+ +
  EEA20898.1 526 LDLKNTINDMVDRLNKFAFEVSK--VAREVgtdgtlggqakvdnvEGKWKDLTDNVNTM 582
                 88888888766555554433322..2222222233333222222222223333333333 PP

>> YL1  YL1 nuclear protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7  14.5    0.0069       3.5      28     115 ..      96     177 ..      64     222 .. 0.53

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0069
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..x RF
         YL1  28 FaEeedDeefeseeeeeeeensDsdfdsdeedeesdeeedeeegekelerqerkkr...kkekkkrkaqkkkskkkkkkqkkkkkkkidp..q 115
                 + +++dD++  +++++e+    Dsd   +e+d+++d+e+d+ + +  l   +r+ r   +     r  q+ + k++   +++ +k  i++  +
  EEA20898.1  96 YDDDDDDDDTGDDDDDED----DSDG--SEDDDDDDNEDDDHAANGVLVTRRRTLRggaE---TLRSLQNHVEKQAH--EISIQKDIIARvrE 177
                 567777777776554443....5445..44444456888888888888888888885431...22222222222222..22223332222321 PP

>> AAA_13  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   1.7     0.091        47     357     471 ..     151     267 ..      55     278 .. 0.76
   2 ?   12.0   4.8   0.00012     0.061     290     446 ..     298     461 ..     295     497 .. 0.68
   3 ?    2.5   3.8     0.087        44     324     447 ..     481     601 ..     467     644 .. 0.58
   4 ?    4.4   4.3     0.022        11     288     464 ..     572     766 ..     562     772 .. 0.51

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.091
      AAA_13 357 lesvkakiesikklvaeineliakhNekvanleeekeeakkklelhlveeleseldeykkkykklekaieklekelkeeeaelkkleeeikeLek..ql 453
                 l s+++ +e+  ++++  +++ia+  e  ++ ee++ +  +k+e+  v  l+ el + +++ ++++ka+ +    +++ ++    ++ +i  Le   ++
  EEA20898.1 151 LRSLQNHVEKQAHEISIQKDIIARVREELDMQEERTRRTLVKVEHEDVGVLQRELRKHQQANEAFQKALREIGGIITQVANGDLSMKVQIHPLEMdpEI 249
                 566666667777777777777777777777777777777777777777777777777777777777777777766666666666666666655532267 PP

      AAA_13 454 rdekpaaeeinkeLkafG 471
                  + k++++ + ++L+ fG
  EEA20898.1 250 ATFKRTINTMMDQLQVFG 267
                 777777777777777776 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 0.00012
      AAA_13 290 kliekveskkselleklkavsde.......asensafeedkeelkaeaealeeqLkglqralea...Krkepfksvelesvkakiesikklvaeineli 378
                 +l e+v+ + ++l++++ ++++        +  +++     + ++ e+ +l+++++++ ++l      +++++++v +e v +   +i+  +   nel 
  EEA20898.1 298 ELTENVNIMAKNLTDQVREIATVttavahgDLSQKI----ESRAHGEIFELQQTINTMVDQLRTfatEVTRVARDVGTEGVLGGQAQIEGVQGMWNELT 392
                 555666666666666666666552211111222222....2333334445555555544444430003456777888899999999************* PP

      AAA_13 379 akhNekvanleeekeeakkklelhlveeleseld.eykkkykklekaieklekelkeeeaelkkleeei 446
                  + N++ +nl++++ ++++  ++    +l+++++ + k ++++l++ i+++ ++l++ ++e+ k+++e+
  EEA20898.1 393 VNVNAMANNLTTQVRDIANVTKAVAKGDLTQKVQaNCKGEIAELKNIINSMVDQLRQFAQEVTKIAKEV 461
                 *******************999999999999999788999**********************9999994 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.087
      AAA_13 324 eelkaeaealeeqLkglqraleaKrkepfksvelesvkakiesikklvaeineliakhNekvanleeekeeakkklelhlveeleseldeykkkykkle 422
                 ++l+++ + ++++L++  r++ +  + ++k   + +v+    +++ ++ +++++i++   + ++++ e+++++ ++  +     ++++d+ + k+k+l+
  EEA20898.1 481 KDLTENVNRMANNLTTHVREIAEVTTAVAKGDLTRKVT---ANVQGEILDLKNTINDMVDRLNKFAFEVSKVAREVGTDGTLGGQAKVDNVEGKWKDLT 576
                 33444444444444444444444444444422222222...3444555555555555555555666777777777777777677778888888888888 PP

      AAA_13 423 kaieklekelkeeeaelkkleeeik 447
                 ++++ + ++l+ + + +  + + i+
  EEA20898.1 577 DNVNTMAQNLTSQVRGISDVTQAIA 601
                 8888888888777777766666643 PP

  == domain 4  score: 4.4 bits;  conditional E-value: 0.022
      AAA_13 288 LekliekveskkselleklkavsdeasensafeedkeelkaeaealeeqLkglqraleaKrkepfk.svelesvkaki.e...............sikk 369
                  ++l ++v+++ ++l+ ++  +sd  ++ +a  +  ++++ +a+     + +l+  +++ +++++k   el++v+ ++ +               + k+
  EEA20898.1 572 WKDLTDNVNTMAQNLTSQVRGISDVTQA-IAKGDLSKKIEVHAQGE---ILTLKVTINNMVDRLAKfATELKRVARDVgVdgkmggqanvegiagRWKE 666
                 5677788888888888888888776654.33333334443333322...33333333333333333223555555555313444444433344443333 PP

      AAA_13 370 lvaeineliakhNekvanleeekeeakk.klelhlveeleseldeyk....kkykklekaieklekelkeeeaelkkleeeikeLekqlrdekpaaeei 463
                 + +++n++ ++   +v  + e + +a++ ++ + +  ++  e+de+k    k +++l ++i+ ++++ +++e++ +++ e  +++  ++r++ +++  +
  EEA20898.1 667 ITEDVNTMAENLTSQVRAFGEITDAATDgDFTKLITVNASGEMDELKrkinKMVSNLRDSIQRNTAAREAAEQANRTKSEFLANMSHEIRTPMNGIIGM 765
                 333333333333333333333333333223444444666666666653333555667777777777777777777777777888888887777776655 PP

      AAA_13 464 n 464
                 +
  EEA20898.1 766 T 766
                 5 PP

>> BORCS6  BLOC-1-related complex sub-unit 6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.1         1   5.4e+02       5      42 ..     303     342 ..     295     372 .. 0.53
   2 ?    4.2   1.6     0.092        47      55      91 ..     470     506 ..     394     527 .. 0.61
   3 ?    5.0   0.1      0.05        26      58      90 ..     565     597 ..     511     607 .. 0.92
   4 ?   -1.0   0.0       3.6   1.9e+03      65      90 ..     664     689 ..     654     694 .. 0.80
   5 ?   -2.1   0.1         8   4.1e+03      77      88 ..     721     732 ..     708     811 .. 0.50

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 1
      BORCS6   5 thFvaedLeekiklsssvskkees..sslsesstpsasls 42 
                 ++ +a++L  +++  ++v++  +    s++ +s + ++++
  EEA20898.1 303 VNIMAKNLTDQVREIATVTTAVAHgdLSQKIESRAHGEIF 342
                 4456777777777766666655541233333344444444 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.092
      BORCS6  55 pnvlsdlereaqkvaasvdnllenlssklhsisaltv 91 
                 +  ++d+e   ++++++v+++ +nl++++++i+ +t 
  EEA20898.1 470 QATVHDVEGTWKDLTENVNRMANNLTTHVREIAEVTT 506
                 4568999999999999999999999999999988875 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.05
      BORCS6  58 lsdlereaqkvaasvdnllenlssklhsisalt 90 
                 ++++e + ++++++v+++ +nl+s+++ is +t
  EEA20898.1 565 VDNVEGKWKDLTDNVNTMAQNLTSQVRGISDVT 597
                 67899999*********************9988 PP

  == domain 4  score: -1.0 bits;  conditional E-value: 3.6
      BORCS6  65 aqkvaasvdnllenlssklhsisalt 90 
                  +++++ v+++ enl+s+++    +t
  EEA20898.1 664 WKEITEDVNTMAENLTSQVRAFGEIT 689
                 57899999999999999998776665 PP

  == domain 5  score: -2.1 bits;  conditional E-value: 8
      BORCS6  77 enlssklhsisa 88 
                 +nl+ ++++ +a
  EEA20898.1 721 SNLRDSIQRNTA 732
                 333333333332 PP

>> Mer2  Mer2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.4      0.22   1.1e+02      91     186 ..     151     244 ..     138     247 .. 0.69
   2 ?    6.7   3.4     0.011       5.9      48     190 ..     298     455 ..     296     459 .. 0.69
   3 ?    7.4   2.7    0.0066       3.4      48     140 ..     482     587 ..     475     591 .. 0.69
   4 ?   -0.6   7.6       1.9   9.8e+02      49     145 ..     575     684 ..     564     763 .. 0.42
   5 ?    1.7   0.0      0.39     2e+02      34      86 ..     767     815 ..     764     849 .. 0.74

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.22
        Mer2  91 ikdLsvkienqlsk..vskavldklkvkkhksntdtksnLtellekkeakileeidkkqtkleksvdttqelllnvnkQledvnevllSlskdlenls 186
                 ++ L+ ++e+q ++  ++k++  ++ ++   ++  t++ L+++  +    + +e++    k +++++  q+ l  ++  + +v +  lS++ +++ l+
  EEA20898.1 151 LRSLQNHVEKQAHEisIQKDIIARVREELDMQEERTRRTLVKVEHEDVGVLQRELR----KHQQANEAFQKALREIGGIITQVANGDLSMKVQIHPLE 244
                 55677777777665115677777777777777777777777766666666655555....55667777777787888887778777788887777765 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.011
        Mer2  48 kLinvlkenskeLlkvisklnellidlkeeesdnskekeikdlikdLsvkienqlskvskavldklk.............vkkhksntdtksnLtelle 133
                 +L++ ++ + k+L++ + ++   +  + +++  ++ e      i +L+ +i+   +++++  ++ +              + + +   +  ++Lt  ++
  EEA20898.1 298 ELTENVNIMAKNLTDQVREIATVTTAVAHGDLSQKIESRAHGEIFELQQTINTMVDQLRTFATEVTRvardvgtegvlggQAQIEGVQGMWNELTVNVN 396
                 678888888888888888888888888887777766666666666666666664333333222222233466667777653444444456678888888 PP

        Mer2 134 kkeakileeidk..kqtkleksvdttqelllnvnkQledvnevllSlskdlenlstrqt 190
                    ++++ ++++  + tk     d+tq++  n+   + ++++++ S+  +l++  +  t
  EEA20898.1 397 AMANNLTTQVRDiaNVTKAVAKGDLTQKVQANCKGEIAELKNIINSMVDQLRQFAQEVT 455
                 8888888888853356677777899***********************99998877655 PP

  == domain 3  score: 7.4 bits;  conditional E-value: 0.0066
        Mer2  48 kLinvlkenskeLlkvisklnellidlkeeesdnskekeikdlikdLsvkienqlskvskavldklk.............vkkhksntdtksnLtelle 133
                  L++ ++++ ++L++ + ++ e +  + +++  ++ + +++  i dL+ +i++  ++++k   +  k             + k ++  ++ ++Lt+ ++
  EEA20898.1 482 DLTENVNRMANNLTTHVREIAEVTTAVAKGDLTRKVTANVQGEILDLKNTINDMVDRLNKFAFEVSKvarevgtdgtlggQAKVDNVEGKWKDLTDNVN 580
                 6999***********************************************995544443322222222233334445553333333444455555555 PP

        Mer2 134 kkeakil 140
                    ++++
  EEA20898.1 581 TMAQNLT 587
                 5555555 PP

  == domain 4  score: -0.6 bits;  conditional E-value: 1.9
        Mer2  49 LinvlkenskeLlkvisklnellidlkeeesdnskekeikdlikdLsvkien...qlskvskavldklk...........vkkhksntdtksnLtelle 133
                 L+  ++ + ++L++ +  + + +  + +++  ++ e + +  i  L+v+i+n    l+k  ++++   +           + + +   +  +++te ++
  EEA20898.1 575 LTDNVNTMAQNLTSQVRGISDVTQAIAKGDLSKKIEVHAQGEILTLKVTINNmvdRLAKFATELKRV-ArdvgvdgkmggQANVEGIAGRWKEITEDVN 672
                 5666666666666666666666666666666555555555566666666666333122222221111.1233333333332222222233333333333 PP

        Mer2 134 kkeakileeidk 145
                    +++++++++
  EEA20898.1 673 TMAENLTSQVRA 684
                 333333333332 PP

  == domain 5  score: 1.7 bits;  conditional E-value: 0.39
        Mer2  34 KLELEsvdLrEksskLinvlkenskeLlkvisklnellidlkeeesdnskeke 86 
                  L L++ dL+    ++ nv+++  + Ll++i+++ ++  +++    ++  +++
  EEA20898.1 767 QLTLDTDDLKPYPREMLNVVHNLANSLLTIIDDILDIS-KIE---ANRMVIES 815
                 58899999***********************9988766.333...34444443 PP

>> DUF5593  Domain of unknown function (DUF5593)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.1       1.3   6.8e+02      22      55 ..     149     183 ..     142     205 .. 0.71
   2 ?    0.0   0.0       2.8   1.4e+03      33      81 ..     245     293 ..     224     298 .. 0.82
   3 ?    4.5   0.1      0.11        57      33      83 ..     337     388 ..     315     391 .. 0.84
   4 ?    3.6   0.1      0.21   1.1e+02      35      81 ..     431     477 ..     409     482 .. 0.87

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 1.3
     DUF5593  22 kewtplasllrrkaalaav.rsaiaevvrsgepvs 55 
                   +++l++++ ++a+   + +++ia v++     +
  EEA20898.1 149 ETLRSLQNHVEKQAHEISIqKDIIARVREELDMQE 183
                 6789************9**5667777776554443 PP

  == domain 2  score: 0.0 bits;  conditional E-value: 2.8
     DUF5593  33 rkaalaavrsaiaevvrsgepvsritpksdrviraepVlgpdgrvhgVq 81 
                   + +a+ ++ i++++++ +   +++++  r++ +e +lg + ++ gV+
  EEA20898.1 245 MDPEIATFKRTINTMMDQLQVFGSEVSRVAREVGTEGILGGQAQITGVH 293
                 456777788888999999888888888999999***********99998 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.11
     DUF5593  33 rkaalaavrsaiaevvrsgepvsritpksdrviraepVlgpdgrvhgVq.vW 83 
                 ++  + ++++ i+++v++ ++ ++++++  r + +e Vlg + ++ gVq +W
  EEA20898.1 337 AHGEIFELQQTINTMVDQLRTFATEVTRVARDVGTEGVLGGQAQIEGVQgMW 388
                 45556788999************999999999****************9555 PP

  == domain 4  score: 3.6 bits;  conditional E-value: 0.21
     DUF5593  35 aalaavrsaiaevvrsgepvsritpksdrviraepVlgpdgrvhgVq 81 
                   +a+++++i+++v++ ++ +++++k  +++ +  Vlg + +vh V+
  EEA20898.1 431 GEIAELKNIINSMVDQLRQFAQEVTKIAKEVGTDGVLGGQATVHDVE 477
                 4678999**************999999999**************985 PP

>> PPP4R2  PPP4R2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4  11.0     0.023        12     240     286 ..      84     130 ..      20     133 .. 0.62

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.023
      PPP4R2 240 eekdesvkveekdddeeddeedtdyveeeeddesedddeeeeeeeee 286
                 +    s+k++ k dd++dd+++ d +++e+d++  +dd+++++e+++
  EEA20898.1  84 KRPRRSRKLKRKYDDDDDDDDTGDDDDDEDDSDGSEDDDDDDNEDDD 130
                 34445555565555555555555544444444433333333333332 PP

>> RXT2_N  RXT2-like, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4  10.7     0.032        17      47      92 ..      87     133 ..      66     140 .. 0.38

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.032
      RXT2_N  47 ierskrkk......kekekeekeeeeedeegdeededdddeeeaeaaeenpy 92 
                 ++++k k+      +++++ +++++e+d++g+e+d+d     ++++++++  
  EEA20898.1  87 RRSRKLKRkyddddDDDDTGDDDDDEDDSDGSEDDDD-----DDNEDDDHAA 133
                 2222222233212122222222222222222222222.....3344444444 PP

>> Phage_Mu_Gam  Bacteriophage Mu Gam like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0       1.8   9.1e+02       5      59 ..     216     268 ..     202     272 .. 0.78
   2 ?    3.2   0.0      0.14        73      30      60 ..     331     361 ..     302     367 .. 0.88
   3 ?    5.3   0.1     0.033        17      30      61 ..     423     454 ..     407     464 .. 0.89
   4 ?   -0.2   0.1       1.7   8.5e+02       6      62 ..     489     547 ..     484     626 .. 0.64
   5 ?   -0.2   0.0       1.6   8.4e+02      30      62 ..     607     639 ..     572     644 .. 0.87
   6 ?    0.8   0.6       0.8   4.1e+02       7      45 ..     705     743 ..     703     754 .. 0.71

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 1.8
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH CS
  Phage_Mu_Gam   5 nwalrkiaelkreleeieaeaneeiaaikekleaeleplkkeieylesllkqYae 59 
                   ++alr+i+ + ++++     ++ +i  +  + + e+++ k  i+ + ++l+ +  
    EEA20898.1 216 QKALREIGGIITQVANGDLSMKVQIHPL--EMDPEIATFKRTINTMMDQLQVFGS 268
                   5677888888888777777777777665..5789999999999999999998865 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.14
                   HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHC CS
  Phage_Mu_Gam  30 aaikekleaeleplkkeieylesllkqYaea 60 
                   ++i+ ++  e+ +l++ i+ + ++l+++a++
    EEA20898.1 331 QKIESRAHGEIFELQQTINTMVDQLRTFATE 361
                   78999***********************987 PP

  == domain 3  score: 5.3 bits;  conditional E-value: 0.033
                   HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCT CS
  Phage_Mu_Gam  30 aaikekleaeleplkkeieylesllkqYaean 61 
                   ++++++ + e+++lk+ i+ + ++l+q+a++ 
    EEA20898.1 423 QKVQANCKGEIAELKNIINSMVDQLRQFAQEV 454
                   68899999*********************986 PP

  == domain 4  score: -0.2 bits;  conditional E-value: 1.7
                   HHHHHHHHHHHHHHHHHHHHHHH..HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCTH CS
  Phage_Mu_Gam   6 walrkiaelkreleeieaeanee..iaaikekleaeleplkkeieylesllkqYaeank 62 
                       ++  + re++e+ + + +     +++++ + e+  lk+ i+++ + l ++a +  
    EEA20898.1 489 RMANNLTTHVREIAEVTTAVAKGdlTRKVTANVQGEILDLKNTINDMVDRLNKFAFEVS 547
                   55556666666666666666543115677788899999999999999999999886655 PP

  == domain 5  score: -0.2 bits;  conditional E-value: 1.6
                   HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCTH CS
  Phage_Mu_Gam  30 aaikekleaeleplkkeieylesllkqYaeank 62 
                   ++i+ +++ e+ +lk  i+ + + l ++a+++k
    EEA20898.1 607 KKIEVHAQGEILTLKVTINNMVDRLAKFATELK 639
                   5788899999999***************99998 PP

  == domain 6  score: 0.8 bits;  conditional E-value: 0.8
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH CS
  Phage_Mu_Gam   7 alrkiaelkreleeieaeaneeiaaikekleaeleplkk 45 
                   a +++ elkr+++++ + + ++i++ +++ ea+ ++  +
    EEA20898.1 705 ASGEMDELKRKINKMVSNLRDSIQRNTAAREAAEQANRT 743
                   567888999999999999999998877666655444444 PP

>> SpoIIID  Stage III sporulation protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.0      0.36   1.9e+02      36      65 ..     295     324 ..     286     328 .. 0.85
   2 ?   -0.6   0.1       2.9   1.5e+03      39      64 ..     390     415 ..     386     428 .. 0.83
   3 ?    4.4   0.2     0.077        40      37      62 ..     480     505 ..     437     520 .. 0.82
   4 ?   -1.5   0.0       5.4   2.7e+03      33      58 ..     529     553 ..     503     557 .. 0.79
   5 ?    2.3   0.0      0.36   1.8e+02      38      64 ..     573     599 ..     560     603 .. 0.91

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.36
     SpoIIID  36 vhkDvterLkkinkklakqvkevLeknkae 65 
                 + k++te ++ + k+l +qv+e+  +  a 
  EEA20898.1 295 IWKELTENVNIMAKNLTDQVREIATVTTAV 324
                 789*******************98776665 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 2.9
     SpoIIID  39 DvterLkkinkklakqvkevLeknka 64 
                 ++t  ++ + ++l +qv+++ ++ ka
  EEA20898.1 390 ELTVNVNAMANNLTTQVRDIANVTKA 415
                 67778888899999999999999887 PP

  == domain 3  score: 4.4 bits;  conditional E-value: 0.077
     SpoIIID  37 hkDvterLkkinkklakqvkevLekn 62 
                  kD+te ++++ ++l ++v+e+ e+ 
  EEA20898.1 480 WKDLTENVNRMANNLTTHVREIAEVT 505
                 39********************9876 PP

  == domain 4  score: -1.5 bits;  conditional E-value: 5.4
     SpoIIID  33 kstvhkDvterLkkinkklakqvkev 58 
                 k t+ +D+ +rL+k   ++ k  +ev
  EEA20898.1 529 KNTI-NDMVDRLNKFAFEVSKVAREV 553
                 5555.699999999998888877776 PP

  == domain 5  score: 2.3 bits;  conditional E-value: 0.36
     SpoIIID  38 kDvterLkkinkklakqvkevLeknka 64 
                 kD+t+ ++++ ++l +qv+ + ++ +a
  EEA20898.1 573 KDLTDNVNTMAQNLTSQVRGISDVTQA 599
                 9******************99988766 PP

>> RNA_pol_3_Rpc31  DNA-directed RNA polymerase III subunit Rpc31
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2  14.3    0.0053       2.7     170     214 ..      88     130 ..      34     134 .. 0.66

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0053
  RNA_pol_3_Rpc31 170 lleklkelaeeeddeeekkekedeeeeeeeeeddefddddedggD 214
                        +klk++ +++dd++++ + +d+e++++  edd+ dd   +++D
       EEA20898.1  88 RSRKLKRKYDDDDDDDDTGDDDDDEDDSDGSEDDDDDDN--EDDD 130
                      457888766666664333333333333233333333322..3555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1313 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1729  (0.0964359); expected 358.6 (0.02)
Passed bias filter:                      844  (0.0470746); expected 358.6 (0.02)
Passed Vit filter:                       136  (0.00758548); expected 17.9 (0.001)
Passed Fwd filter:                        58  (0.00323498); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              35  [number of targets reported over threshold]
# CPU time: 1.43u 0.34s 00:00:01.77 Elapsed: 00:00:00.51
# Mc/sec: 7758.24
//
Query:       EEA20899.1  [L=1319]
Description: two-component osmosensing histidine kinase (Bos1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.4e-42  143.8  15.5    1.5e-08   34.9   0.0    7.4  7  HAMP             HAMP domain
    2.9e-33  114.7   0.4    2.2e-32  111.9   0.1    2.6  2  HATPase_c        Histidine kinase-, DNA gyrase B-, and HSP90-
    1.2e-25   89.8   0.9    4.6e-25   88.0   0.5    2.3  1  Response_reg     Response regulator receiver domain
    4.7e-16   58.6   5.0    4.9e-16   58.5   0.1    3.8  3  HisKA            His Kinase A (phospho-acceptor) domain
    8.8e-12   44.8   6.2     0.0035   16.5   0.0    5.6  3  APG17            Autophagy protein Apg17
    4.5e-07   30.2  13.0       0.73   10.2   0.0    6.6  5  Syntaxin_2       Syntaxin-like protein
    4.7e-05   23.6   0.0         13    6.0   0.0    5.5  5  DUF4279          Domain of unknown function (DUF4279)
     0.0021   18.3  53.1        1.6    9.1   0.2    9.9  5  DUF948           Bacterial protein of unknown function (DUF94
     0.0026   17.8   4.9     0.0026   17.8   4.9    6.9  5  Baculo_PEP_C     Baculovirus polyhedron envelope protein, PEP
     0.0044   17.2  24.5        3.2    8.1   0.7    8.1  7  WXG100           Proteins of 100 residues with WXG
  ------ inclusion threshold ------
      0.013   16.0   5.0         27    5.4   0.0    5.9  5  DUF1843          Domain of unknown function (DUF1843)
      0.021   14.3  15.2       0.17   11.3   0.6    5.0  6  DUF3829          Protein of unknown function (DUF3829)
      0.024   15.0   4.9         45    4.4   0.1    4.9  5  Gp-FAR-1         Nematode fatty acid retinoid binding protein
      0.026   14.1  22.2       0.46   10.1   5.3    4.9  5  DUF4795          Domain of unknown function (DUF4795)
       0.03   14.5  30.6       0.87    9.8   0.7    7.2  7  Fib_alpha        Fibrinogen alpha/beta chain family
      0.043   13.4   0.0        6.3    6.5   0.0    2.7  2  NOD              NOTCH protein
      0.088   12.4   0.1       0.28   10.8   0.1    1.8  1  IcmF_C           Type VI secretion protein IcmF C-terminal
      0.097   12.7   2.5        2.1    8.3   0.1    2.8  2  PA-IL            PA-IL-like protein
       0.11   12.6   0.3         13    5.9   0.0    3.5  3  CMD              Carboxymuconolactone decarboxylase family
       0.12   11.4  17.3       0.22   10.6  17.3    1.3  1  DUF2457          Protein of unknown function (DUF2457)
        0.3   11.1  31.4       0.68    9.9   0.1    8.2  7  CENP-F_leu_zip   Leucine-rich repeats of kinetochore protein 
       0.31   10.2   9.1        9.5    5.3   0.0    4.3  5  GLE1             GLE1-like protein
       0.76    7.8  20.3       0.13   10.4  16.4    1.6  2  DNA_pol_phi      DNA polymerase phi
       0.93    9.4   6.4         26    4.7   0.0    4.8  4  DUF1759          Protein of unknown function (DUF1759)
        1.3    9.4  20.7         15    6.0   3.2    4.3  2  Fez1             Fez1
        1.5    8.9  14.5        3.6    7.6  14.5    1.6  1  YL1              YL1 nuclear protein
        1.8    7.1  29.1      0.062   11.9   4.7    4.0  4  AAA_13           AAA domain
        2.6    8.3  12.5         26    5.0   0.1    5.3  5  BORCS6           BLOC-1-related complex sub-unit 6
        2.7    7.7  34.3        3.4    7.4   2.7    6.2  5  Mer2             Mer2
        3.5    8.4   9.3         57    4.5   0.1    5.0  4  DUF5593          Domain of unknown function (DUF5593)
          4    6.9  11.0         12    5.4  11.0    1.8  1  PPP4R2           PPP4R2
        4.8    7.2  10.7         17    5.4  10.7    1.9  1  RXT2_N           RXT2-like, N-terminal
        5.5    6.9  13.8         16    5.4   0.3    5.5  6  Phage_Mu_Gam     Bacteriophage Mu Gam like protein
        6.6    6.9  11.9         40    4.4   0.2    5.9  5  SpoIIID          Stage III sporulation protein D
        7.5    6.7  17.3        2.7    8.2  14.3    1.8  1  RNA_pol_3_Rpc31  DNA-directed RNA polymerase III subunit Rpc3


Domain annotation for each model (and alignments):
>> HAMP  HAMP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.0     0.038        20      10      52 ..     219     264 ..     216     265 .. 0.89
   2 !   33.5   0.1   7.6e-11   3.9e-08       2      52 ..     306     356 ..     305     357 .. 0.96
   3 !   27.8   0.0   4.9e-09   2.5e-06       2      53 .]     398     449 ..     397     449 .. 0.97
   4 ?   -0.3   0.0       2.8   1.5e+03      40      52 ..     483     495 ..     482     496 .. 0.86
   5 !   30.9   0.4     5e-10   2.6e-07       2      52 ..     490     540 ..     489     541 .. 0.95
   6 !   34.9   0.0     3e-11   1.5e-08       2      51 ..     582     631 ..     581     633 .. 0.95
   7 !   15.8   0.1   2.6e-05     0.013      15      53 .]     687     725 ..     674     725 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.038
                 HHHHHHHHHHHTTTBTSST..CCT.TSSSHHHHHHHHHHHHHHHHH CS
        HAMP  10 LrrLaraarriaaGdldtr..lpv.sgrDEiGeLarafNaMldrLr 52 
                 Lr++   + ++a+Gdl+    + + + + Ei++  r++N+M+d+L+
  EEA20899.1 219 LREIGGIITQVANGDLSMKvqIHPlEMDPEIATFKRTINTMMDQLQ 264
                 6777777899****9999988999999*****************97 PP

  == domain 2  score: 33.5 bits;  conditional E-value: 7.6e-11
                 HHHTTHHHHHHHHHHHHHHTTTBTSSTCCTTSSSHHHHHHHHHHHHHHHHH CS
        HAMP   2 larrilrPLrrLaraarriaaGdldtrlpvsgrDEiGeLarafNaMldrLr 52 
                 +a++++  +r++a+++ ++a+Gdl++ ++ +   Ei eL +++N+M+d+Lr
  EEA20899.1 306 MAKNLTDQVREIATVTTAVAHGDLSQKIESRAHGEIFELQQTINTMVDQLR 356
                 78999999******************************************8 PP

  == domain 3  score: 27.8 bits;  conditional E-value: 4.9e-09
                 HHHTTHHHHHHHHHHHHHHTTTBTSSTCCTTSSSHHHHHHHHHHHHHHHHHH CS
        HAMP   2 larrilrPLrrLaraarriaaGdldtrlpvsgrDEiGeLarafNaMldrLre 53 
                 +a++++  +r +a +++++a+Gdl++ +  + + Ei+eL   +N M+d+Lr+
  EEA20899.1 398 MANNLTTQVRDIANVTKAVAKGDLTQKVQANCKGEIAELKNIINSMVDQLRQ 449
                 78999*********************************************97 PP

  == domain 4  score: -0.3 bits;  conditional E-value: 2.8
                 HHHHHHHHHHHHH CS
        HAMP  40 LarafNaMldrLr 52 
                 L +++N+M+++L 
  EEA20899.1 483 LTENVNRMANNLT 495
                 8899******995 PP

  == domain 5  score: 30.9 bits;  conditional E-value: 5e-10
                 HHHTTHHHHHHHHHHHHHHTTTBTSSTCCTTSSSHHHHHHHHHHHHHHHHH CS
        HAMP   2 larrilrPLrrLaraarriaaGdldtrlpvsgrDEiGeLarafNaMldrLr 52 
                 +a++++  +r++a+++ ++a+Gdl+  ++ + + Ei +L  ++N+M+drL+
  EEA20899.1 490 MANNLTTHVREIAEVTTAVAKGDLTRKVTANVQGEILDLKNTINDMVDRLN 540
                 788899999*****************************************8 PP

  == domain 6  score: 34.9 bits;  conditional E-value: 3e-11
                 HHHTTHHHHHHHHHHHHHHTTTBTSSTCCTTSSSHHHHHHHHHHHHHHHH CS
        HAMP   2 larrilrPLrrLaraarriaaGdldtrlpvsgrDEiGeLarafNaMldrL 51 
                 +a +++  +r +++++++ia+Gdl++ ++v+ + Ei +L  ++N+M+drL
  EEA20899.1 582 MAQNLTSQVRGISDVTQAIAKGDLSKKIEVHAQGEILTLKVTINNMVDRL 631
                 57789999*****************************************9 PP

  == domain 7  score: 15.8 bits;  conditional E-value: 2.6e-05
                 HHHHHHTTTBTSSTCCTTSSSHHHHHHHHHHHHHHHHHH CS
        HAMP  15 raarriaaGdldtrlpvsgrDEiGeLarafNaMldrLre 53 
                 + +++  +Gd+++ ++v+   E++eL r +N M+ +Lr+
  EEA20899.1 687 EITDAATDGDFTKLITVNASGEMDELKRKINKMVSNLRD 725
                 34455557*****************************96 PP

>> HATPase_c  Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0       6.1   3.1e+03       6      26 ..     620     640 ..     615     679 .. 0.75
   2 !  111.9   0.1   4.3e-35   2.2e-32       1     108 [.     856     971 ..     856     975 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 6.1
                 HHHHHHHHHHHHHHHHSTTTE CS
   HATPase_c   6 LrqiisnlvdNavkfatkage 26 
                 L+  i+n+vd ++kfat+ ++
  EEA20899.1 620 LKVTINNMVDRLAKFATELKR 640
                 677899999999999665443 PP

  == domain 2  score: 111.9 bits;  conditional E-value: 4.3e-35
                 EHHHHHHHHHHHHHHHHHHHHSTTTEEEEEEEEEE........TEEEEEEEESSSSSTTHHHTGTCSTTCH.HCSTCHTSTSSSHHHHHHHHHHHHTTT CS
   HATPase_c   1 gdekrLrqiisnlvdNavkfatkageieveikase........ddlvisveDnGiGipkedlkklfekfsq.ddstkrggggtGlGlsivkklvelmgG 90 
                 gd+ rLrqii nlv+Na+kf t+ ge++++i++se          +++sv+D+GiGi +++l+++f+ f+q d+st+r+ ggtGlGlsi+k+lv+lmgG
  EEA20899.1 856 GDPFRLRQIILNLVGNAIKF-TEHGEVKLTISKSEreqcardeYAFEFSVSDTGIGIEEDKLDLIFDTFQQaDGSTTRRFGGTGLGLSISKRLVNLMGG 953
                 6889****************.99*********8434456666699999*************************************************** PP

                 EEEEEEETTTEEEEEEEE CS
   HATPase_c  91 eiwvesepgrGttftftl 108
                 ++wv+se g+G+tf+ft 
  EEA20899.1 954 DVWVTSEYGHGSTFHFTC 971
                 ***************975 PP

>> Response_reg  Response regulator receiver domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.0   0.5   8.9e-28   4.6e-25       1     111 [.    1129    1243 ..    1129    1244 .. 0.96

  Alignments for each domain:
  == domain 1  score: 88.0 bits;  conditional E-value: 8.9e-28
                    EEEESSSHHHHHHHHHHHHHTTEEEEEEESSHHHHHHHHHHHHESEEEEESSCSSSEHHHHHHHHHHCT.....TTSEEEEEESSTSHHHHHHHH CS
  Response_reg    1 vlivdDdplvrellrqlleeegyeevaeaedgkealellkeekvdlillDinmpgmdGlellkeireed.....pelpviiltahseeedaveal 90  
                    +l+++D++++++l  ++le+ +   v+++ +g+eal+ +k++++d+il+D++mp m G+e++ +ire +     + +p+i+ltah+   d+++++
    EEA20899.1 1129 ILLAEDNEVNQKLAVKILEKCNH-GVTVVGNGQEALDAVKNRRFDIILMDVQMPIMGGFEATAKIREYErennlSRTPIIALTAHAMLGDREKCI 1222
                    89*****************9999.99***************************************99987667777******************* PP

                    HCTESEEEESSG-HHHHHHHH CS
  Response_reg   91 kagaddflsKpfdpeeLlkal 111 
                    +a +d++lsKp++++++++ +
    EEA20899.1 1223 QAQMDEYLSKPLKQNQMIQTI 1243
                    *****************9976 PP

>> HisKA  His Kinase A (phospho-acceptor) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       7.5   3.8e+03      49      63 ..     346     360 ..     303     362 .. 0.69
   2 !   58.5   0.1   9.5e-19   4.9e-16       2      66 ..     744     808 ..     743     809 .. 0.96
   3 ?   -1.7   0.0       5.9     3e+03      14      54 ..    1203    1243 ..    1203    1248 .. 0.50

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 7.5
                 HHHHHHHHHHHHHCC CS
       HisKA  49 rrldhlvedlLdlsr 63 
                 + ++ +v++l+++++
  EEA20899.1 346 QTINTMVDQLRTFAT 360
                 377788888887775 PP

  == domain 2  score: 58.5 bits;  conditional E-value: 9.5e-19
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHC..T-HSSCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH CS
       HisKA   2 lgrflagvaHELrtPLsailgnaeaLkregklteelkeyletiesearrldhlvedlLdlsriea 66 
                 +++fla+++HE+rtP+++i+g++++  ++++l +  +e+l+++++ a+ l+ +++d+Ld+s+iea
  EEA20899.1 744 KSEFLANMSHEIRTPMNGIIGMTQLTLDTDDLKPYPREMLNVVHNLANSLLTIIDDILDISKIEA 808
                 89***********************98888999******************************98 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 5.9
                  HHHHHHHHHHHHHHHC..........T-HSSCHHHHHHHHHHHHHHHHH CS
       HisKA   14 rtPLsailgnaeaLkre........gklteelkeyletiesearrldhl 54  
                  rtP+ a+ + a +  re        +        yl +  ++ + ++ +
  EEA20899.1 1203 RTPIIALTAHAMLGDREkciqaqmdE--------YLSKPLKQNQMIQTI 1243
                  67777776666666665564444441........444444444433333 PP

>> APG17  Autophagy protein Apg17
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.7   0.5    0.0002       0.1     116     281 ..     193     408 ..     131     418 .. 0.56
   2 !   16.5   0.0   6.9e-06    0.0035     122     273 ..     423     584 ..     416     600 .. 0.69
   3 !   10.0   0.3   0.00066      0.34     130     247 ..     615     800 ..     592     811 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.0002
                 S--TTTTHHHHHHHHH........................................HHHHHHHHHHHHTTHH..HHHHHHHHHHH......-------S CS
       APG17 116 vdedsveelkealkes........................................idelqaaqkkldssllefdtdlrelkkel......skskskse 168
                 v +++v  l+++l++                                         i+ ++++ + + ++l+ f ++++ + +e+           +++
  EEA20899.1 193 VEHEDVGVLQRELRKHqqaneafqkalreiggiitqvangdlsmkvqihplemdpeIATFKRTINTMMDQLQVFGSEVSRVAREVgtegilG----GQA 287
                 33333333333332222333333333333366666666666666666666666666888888888888888888888888888886644331....447 PP

                 TCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH...................S-CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.....HHHHH CS
       APG17 169 ssslipellkelesleeemAslLesLtnHfDqcvkAvkltegggal.rraaae..lseeereelleVlekDaaeledVvkelqerleem.....ekakk 259
                 + + ++ + kel++  + mA+ L+  ++    +++Av + + +++  +ra++e    ++  + +++ l   a+e+  V +++ ++         e ++ 
  EEA20899.1 288 QITGVHGIWKELTENVNIMAKNLTDQVREIATVTTAVAHGDLSQKIeSRAHGEifELQQTINTMVDQLRTFATEVTRVARDVGTEGVLGgqaqiEGVQG 386
                 888888888888888888888888888888888888888877777777777775533444577788888888888777777766543333222255555 PP

                 HHHHHHHHHHHHHHHHHHHHHH CS
       APG17 260 llsekkeeiekllsalkkalee 281
                  ++e + +++++ ++l+ ++++
  EEA20899.1 387 MWNELTVNVNAMANNLTTQVRD 408
                 5555555555555555555555 PP

  == domain 2  score: 16.5 bits;  conditional E-value: 6.9e-06
                 THHHHHHHHHHHHHHHHHHHHHTTHH..HHHHHHHHHHH..-------STCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.............. CS
       APG17 122 eelkealkesidelqaaqkkldssllefdtdlrelkkel..sksksksessslipellkelesleeemAslLesLtnHfDqcvkAvkltegggal.rra 217
                 ++++ + k +i+el+++ +++ ++l++f ++++++ ke+  +    ++++ + ++   k+l++  ++mA+ L+  ++    +++Av     g  l r+ 
  EEA20899.1 423 QKVQANCKGEIAELKNIINSMVDQLRQFAQEVTKIAKEVgtDGVLGGQATVHDVEGTWKDLTENVNRMANNLTTHVREIAEVTTAVAK---GD-LtRKV 517
                 6778888999*****************************88334456699999999*************9988777766666666553...33.44555 PP

                 ..........S-CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.....HHHHHHHHHHHHHHHHHHH CS
       APG17 218 aae.......lseeereelleVlekDaaeledVvkelqerleem.....ekakkllsekkeeieklls 273
                 +a+       l ++  +++++ l k a e+++V +e+ +           ++   +++ +++++++ +
  EEA20899.1 518 TANvqgeildL-KNTINDMVDRLNKFAFEVSKVAREVGTDGTLGgqakvDNVEGKWKDLTDNVNTMAQ 584
                 55555567432.22357788888888888888888887766555533334444444444444444444 PP

  == domain 3  score: 10.0 bits;  conditional E-value: 0.00066
                 HHHHHHHHHHHHHHTTHH..HHHHHHHHHHH..-------STCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH...................... CS
       APG17 130 esidelqaaqkkldssllefdtdlrelkkel..sksksksessslipellkelesleeemAslLesLtnHfDqcvkAvkltegggalrraaae...... 220
                  +i  l+ + +++ ++l +f t+l+ + + +  + +  ++++ + i    ke ++  + mA+ L+s ++ f   + A   t+g+   + ++++      
  EEA20899.1 615 GEILTLKVTINNMVDRLAKFATELKRVARDVgvDGKMGGQANVEGIAGRWKEITEDVNTMAENLTSQVRAFGEITDA--ATDGDFT-KLITVNasgemd 710
                 447778888899999999*************9854566779***********************************9..4454432.445555556677 PP

                 ...........................................................S-CCH....HHHHHHHHHHHHHHHHHHHHHH CS
       APG17 221 ...........................................................lseee....reelleVlekDaaeledVvkel 247
                                                                            l+ ++     +e+l+V+++ a+ l  +++++
  EEA20899.1 711 elkrkinkmvsnlrdsiqrntaareaaeqanrtkseflanmsheirtpmngiigmtqltLDTDDlkpyPREMLNVVHNLANSLLTIIDDI 800
                 777777777777777777777777777777777777777777777777777777666664444444444677777777777766666666 PP

>> Syntaxin_2  Syntaxin-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.049        25       3      63 ..     261     324 ..     259     336 .. 0.86
   2 ?    5.1   0.0     0.057        29       4      72 ..     354     427 ..     337     442 .. 0.68
   3 !   10.2   0.0    0.0014      0.73       3      65 ..     445     510 ..     443     527 .. 0.87
   4 ?    6.7   0.0     0.019       9.5       5      62 ..     539     599 ..     535     619 .. 0.81
   5 ?    5.0   0.3      0.06        31      26      94 ..     655     732 ..     622     739 .. 0.65

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.049
  Syntaxin_2   3 snlqkinsnvstleklvkq...Lgtkkdteelreklhelieeinelikktnellkklsqldnss 63 
                 ++lq + s vs   + v +   Lg + + + ++   +el+e++n ++k+ +++++++++++   
  EEA20899.1 261 DQLQVFGSEVSRVAREVGTegiLGGQAQITGVHGIWKELTENVNIMAKNLTDQVREIATVTTAV 324
                 689999999999999999999999999999999999*********************9988765 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.057
  Syntaxin_2   4 nlqkinsnvstleklvkq...Lgtkkdteelreklhelieeinelikktnellkklsqldnsssds..qqklqk 72 
                 +l ++++ v+   + v +   Lg + + e ++   +el+ ++n ++++ + ++++++++++   +   +qk+q+
  EEA20899.1 354 QLRTFATEVTRVARDVGTegvLGGQAQIEGVQGMWNELTVNVNAMANNLTTQVRDIANVTKAVAKGdlTQKVQA 427
                 33444444444444444444444444577777888999999999999999999999999988866677777764 PP

  == domain 3  score: 10.2 bits;  conditional E-value: 0.0014
  Syntaxin_2   3 snlqkinsnvstleklvkq...Lgtkkdteelreklhelieeinelikktnellkklsqldnsssd 65 
                 ++l ++++ v+++ k v +   Lg +    ++    ++l+e++n+++++ + +++++++++    +
  EEA20899.1 445 DQLRQFAQEVTKIAKEVGTdgvLGGQATVHDVEGTWKDLTENVNRMANNLTTHVREIAEVTTAVAK 510
                 699***************99*************************************999877654 PP

  == domain 4  score: 6.7 bits;  conditional E-value: 0.019
  Syntaxin_2   5 lqkinsnvstleklvkq...Lgtkkdteelreklhelieeinelikktnellkklsqldns 62 
                 l k++  vs+  + v +   Lg +   +++  k ++l++++n+++++ +++++ +s +++ 
  EEA20899.1 539 LNKFAFEVSKVAREVGTdgtLGGQAKVDNVEGKWKDLTDNVNTMAQNLTSQVRGISDVTQA 599
                 66777777777777777777999999**************************999988765 PP

  == domain 5  score: 5.0 bits;  conditional E-value: 0.06
  Syntaxin_2  26 kdteelreklhelieeinelikktnellkklsqldnsssds........qqklqkekLkkdfkealqeFq.kiqrqya 94 
                  + e +  + +e++e++n+++++ +++++ + ++++   d         +   + + Lk+++++ ++++  +iqr+ a
  EEA20899.1 655 ANVEGIAGRWKEITEDVNTMAENLTSQVRAFGEITDAATDGdftklitvNASGEMDELKRKINKMVSNLRdSIQRNTA 732
                 446666777888999999999999999999999888887778866655533336666777777666666523444444 PP

>> DUF4279  Domain of unknown function (DUF4279)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0       5.6   2.8e+03      51      81 ..     251     281 ..     246     286 .. 0.85
   2 ?    1.7   0.0      0.56   2.9e+02      51      84 ..     343     376 ..     333     407 .. 0.83
   3 ?    6.0   0.0     0.026        13      50     109 ..     434     493 ..     423     507 .. 0.80
   4 ?    3.7   0.0      0.13        67      50      84 ..     526     560 ..     515     588 .. 0.83
   5 ?    3.7   0.0      0.14        70      50      79 ..     618     647 ..     608     658 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 5.6
     DUF4279  51 dleeqldklldrlepkaekikelakkyglei 81 
                 +++  ++++ d+l+ + +++ ++a++ g e 
  EEA20899.1 251 TFKRTINTMMDQLQVFGSEVSRVAREVGTEG 281
                 6788899**************9999887765 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.56
     DUF4279  51 dleeqldklldrlepkaekikelakkygleiylq 84 
                 +l+  +++++d+l  +a ++ ++a++ g e +l+
  EEA20899.1 343 ELQQTINTMVDQLRTFATEVTRVARDVGTEGVLG 376
                 68889********************999887765 PP

  == domain 3  score: 6.0 bits;  conditional E-value: 0.026
     DUF4279  50 ldleeqldklldrlepkaekikelakkygleiylqvviyiedgeqpelhldkevleflaa 109
                  +l++ +++++d+l ++a+++ ++ak+ g + +l+   +++d e++   l   v +++++
  EEA20899.1 434 AELKNIINSMVDQLRQFAQEVTKIAKEVGTDGVLGGQATVHDVEGTWKDLTENVNRMANN 493
                 578999*********************999998877666666665544666666666655 PP

  == domain 4  score: 3.7 bits;  conditional E-value: 0.13
     DUF4279  50 ldleeqldklldrlepkaekikelakkygleiylq 84 
                 ldl++ +++++drl+++a ++ ++a++ g + +l+
  EEA20899.1 526 LDLKNTINDMVDRLNKFAFEVSKVAREVGTDGTLG 560
                 7999**********************988887775 PP

  == domain 5  score: 3.7 bits;  conditional E-value: 0.14
     DUF4279  50 ldleeqldklldrlepkaekikelakkygl 79 
                 l+l+  ++ ++drl ++a ++k++a++ g+
  EEA20899.1 618 LTLKVTINNMVDRLAKFATELKRVARDVGV 647
                 678999*******************98766 PP

>> DUF948  Bacterial protein of unknown function (DUF948)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.2       3.8   1.9e+03      24      49 ..     140     165 ..     135     231 .. 0.69
   2 ?    7.1   2.0     0.013       6.6      40      79 ..     287     326 ..     243     337 .. 0.74
   3 ?    6.5   6.0      0.02        10      23      79 ..     354     418 ..     341     427 .. 0.78
   4 !    9.1   0.2    0.0031       1.6      20      79 ..     627     694 ..     617     696 .. 0.75
   5 ?    0.2   0.1       1.8   9.4e+02      46      78 ..     706     738 ..     699     748 .. 0.59

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 3.8
      DUF948  24 lkktldeaaatieelekqvdpilkev 49 
                  ++tl+  a+t+++l+++v++  +e+
  EEA20899.1 140 RRRTLRGGAETLRSLQNHVEKQAHEI 165
                 56677777777777776666665554 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.013
      DUF948  40 kqvdpilkevedllakvnelledvneklekvdplteavad 79 
                  q++++    ++l+++vn +++++++++ ++ ++t+ava+
  EEA20899.1 287 AQITGVHGIWKELTENVNIMAKNLTDQVREIATVTTAVAH 326
                 6777777777899999999*****************9973 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.02
      DUF948  23 klkktldeaaatieele........kqvdpilkevedllakvnelledvneklekvdplteavad 79 
                 +l+  ++e+++  ++++         q++++    ++l+ +vn+++++++ ++ ++ ++t+ava+
  EEA20899.1 354 QLRTFATEVTRVARDVGtegvlggqAQIEGVQGMWNELTVNVNAMANNLTTQVRDIANVTKAVAK 418
                 34444455555555555999999999*************************************85 PP

  == domain 4  score: 9.1 bits;  conditional E-value: 0.0031
      DUF948  20 vllklkktldeaaatieele........kqvdpilkevedllakvnelledvneklekvdplteavad 79 
                 ++ +l+k ++e+++  ++++         +v++i    +++++ vn+++e++++++ +  ++t+a+ d
  EEA20899.1 627 MVDRLAKFATELKRVARDVGvdgkmggqANVEGIAGRWKEITEDVNTMAENLTSQVRAFGEITDAATD 694
                 33344555555555555555999999989999999999999999999999999999999999999865 PP

  == domain 5  score: 0.2 bits;  conditional E-value: 1.8
      DUF948  46 lkevedllakvnelledvneklekvdplteava 78 
                 + e+++l +k+n++++++++ +++  +  ea++
  EEA20899.1 706 SGEMDELKRKINKMVSNLRDSIQRNTAAREAAE 738
                 455666666666666666665555555555544 PP

>> Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.5      0.43   2.2e+02      35      91 ..     251     318 ..     217     333 .. 0.67
   2 ?    3.9   8.4     0.098        50      32     115 ..     341     409 ..     284     427 .. 0.46
   3 !   17.8   4.9     5e-06    0.0026       6     121 ..     424     545 ..     419     558 .. 0.80
   4 ?    3.5   1.3      0.13        68      56      83 ..     570     597 ..     562     646 .. 0.44
   5 ?    0.2   4.1       1.4   7.3e+02      49      81 ..     666     687 ..     616     805 .. 0.63

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.43
  Baculo_PEP_C  35 qlatlldaietqLnalsedlksllaeldt...........rldtlltnLtdalnalqdtlrneLtnln 91 
                     +++++++  qL+ + ++++++  e+ t            ++   ++Lt+ +n ++++l+ +   + 
    EEA20899.1 251 TFKRTINTMMDQLQVFGSEVSRVAREVGTegilggqaqitGVHGIWKELTENVNIMAKNLTDQVREIA 318
                   55566666666677777777777777766666666666665555555555555555544444443333 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.098
  Baculo_PEP_C  32 ilaqlatlldaietqLnalsedlksllaeldt...........rldtlltnLtdalnalqdtlrneLtnlnsiltnLlssvtNinstLnnllqal 115
                   i  +l+++++++  qL +++++++++  ++ t            ++ + ++Lt  +na++++l+++                         + ++
    EEA20899.1 341 I-FELQQTINTMVDQLRTFATEVTRVARDVGTegvlggqaqieGVQGMWNELTVNVNAMANNLTTQ-------------------------VRDI 409
                   2.3344444444444444444444444444444444444444433333344444444333222222.........................2222 PP

  == domain 3  score: 17.8 bits;  conditional E-value: 5e-06
  Baculo_PEP_C   6 qLnggggnqfldLtnvLnairlqnvqilaqlatlldai..etqL..nalsedlksllaeldtrldtlltnLtdalnalq..dtlrneLtnlnsiltn 96 
                   ++  +  ++  +L n++n++  q+ q + +++++ +++  +++L  +a  +d++   ++l+++++ +++nLt+ + +++  +t   + + + ++ +n
    EEA20899.1 424 KVQANCKGEIAELKNIINSMVDQLRQFAQEVTKIAKEVgtDGVLggQATVHDVEGTWKDLTENVNRMANNLTTHVREIAevTTAVAKGDLTRKVTAN 520
                   45667778899*********999999999999999988334567334667899**************************55444444455677778* PP

  Baculo_PEP_C  97 LlssvtNinstLnnllqalnnldlg 121
                    + ++  +++t+n ++  ln ++ +
    EEA20899.1 521 VQGEILDLKNTINDMVDRLNKFAFE 545
                   *******************998654 PP

  == domain 4  score: 3.5 bits;  conditional E-value: 0.13
  Baculo_PEP_C  56 sllaeldtrldtlltnLtdalnalqdtl 83 
                      ++l+++++t+++nLt+++  ++d  
    EEA20899.1 570 GKWKDLTDNVNTMAQNLTSQVRGISDVT 597
                   3344455555555555555555555221 PP

  == domain 5  score: 0.2 bits;  conditional E-value: 1.4
  Baculo_PEP_C  49 alsedlksllaeldtrldtlltnLtdalnalqd 81 
                   +++ed++ + ++l+++           + a+ +
    EEA20899.1 666 EITEDVNTMAENLTSQ-----------VRAFGE 687
                   3333333333333332...........222221 PP

>> WXG100  Proteins of 100 residues with WXG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.1       9.1   4.7e+03      57      77 ..     209     229 ..     202     232 .. 0.52
   2 ?    1.7   0.0      0.61   3.1e+02       2      36 ..     238     272 ..     237     277 .. 0.79
   3 ?    6.5   0.2     0.019       9.9      15      79 ..     302     367 ..     296     370 .. 0.92
   4 !    8.1   0.7    0.0062       3.2      15      80 ..     394     460 ..     383     463 .. 0.94
   5 ?    3.5   0.0      0.17        87      50      83 ..     477     510 ..     469     512 .. 0.86
   6 ?    4.8   0.1     0.064        33      14      79 ..     577     643 ..     560     646 .. 0.90
   7 ?    3.0   0.7      0.23   1.2e+02      47      84 ..     703     740 ..     656     742 .. 0.71

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 9.1
                 HHHHHHHHHHHHHHHHHHHHH CS
      WXG100  57 kqaaqklvdaLeeisealkqa 77 
                 +qa + +++aL ei+  ++q+
  EEA20899.1 209 QQANEAFQKALREIGGIITQV 229
                 444445555555555444444 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.61
                 HCSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      WXG100   2 ikvdpeelrqaaarfqkqaeeledelqrlkaevda 36 
                 +++ p e++  +a+f+++ ++++d+lq   +ev+ 
  EEA20899.1 238 VQIHPLEMDPEIATFKRTINTMMDQLQVFGSEVSR 272
                 68888899999999999999999999877777665 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.019
                 HHHHHHHHHHHHHHHHHHHHHHC.GCGCTHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      WXG100  15 rfqkqaeeledelqrlkaevdal.qsgWsGaaadafqaefeewkqaaqklvdaLeeisealkqaan 79 
                 +++  a++l+d++++++    a+ +++ s +  ++ ++e+ e++q+++++vd+L + + +++++a+
  EEA20899.1 302 NVNIMAKNLTDQVREIATVTTAVaHGDLSQKIESRAHGEIFELQQTINTMVDQLRTFATEVTRVAR 367
                 566779999**************9************************************999986 PP

  == domain 4  score: 8.1 bits;  conditional E-value: 0.0062
                 HHHHHHHHHHHHHHHHHHHHHHC.GCGCTHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      WXG100  15 rfqkqaeeledelqrlkaevdal.qsgWsGaaadafqaefeewkqaaqklvdaLeeisealkqaana 80 
                 ++++ a++l+++++++++  +a+ +++   + +  +++e++e+k+ ++ +vd+L + +++++++a++
  EEA20899.1 394 NVNAMANNLTTQVRDIANVTKAVaKGDLTQKVQANCKGEIAELKNIINSMVDQLRQFAQEVTKIAKE 460
                 6888999*********************************************************986 PP

  == domain 5  score: 3.5 bits;  conditional E-value: 0.17
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      WXG100  50 qaefeewkqaaqklvdaLeeisealkqaanafed 83 
                 +++++ +++++++++++L+++ +++ ++++a+++
  EEA20899.1 477 EGTWKDLTENVNRMANNLTTHVREIAEVTTAVAK 510
                 678999***************9999999888776 PP

  == domain 6  score: 4.8 bits;  conditional E-value: 0.064
                 HHHHHHHHHHHHHHHHHHHHHHHC.GCGCTHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      WXG100  14 arfqkqaeeledelqrlkaevdal.qsgWsGaaadafqaefeewkqaaqklvdaLeeisealkqaan 79 
                  ++++ a++l+++++ +    +a+ +++ s +  +  q+e+  +k +++++vd L++ + +lk++a+
  EEA20899.1 577 DNVNTMAQNLTSQVRGISDVTQAIaKGDLSKKIEVHAQGEILTLKVTINNMVDRLAKFATELKRVAR 643
                 6788999999999999999999999999999999999999999999999999999999999999886 PP

  == domain 7  score: 3.0 bits;  conditional E-value: 0.23
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      WXG100  47 dafqaefeewkqaaqklvdaLeeisealkqaanafeda 84 
                 +   +e++e+k++++k+v +L +  +  ++a +a e+a
  EEA20899.1 703 VNASGEMDELKRKINKMVSNLRDSIQRNTAAREAAEQA 740
                 56678999999999999999998888777777766665 PP

>> DUF1843  Domain of unknown function (DUF1843)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.55   2.8e+02       6      43 ..     319     355 ..     318     362 .. 0.64
   2 ?    2.0   0.1      0.59     3e+02       8      43 ..     413     447 ..     410     457 .. 0.62
   3 ?    0.6   0.0       1.6   8.2e+02       8      43 ..     505     539 ..     502     549 .. 0.70
   4 ?    5.4   0.0     0.053        27       8      27 ..     597     616 ..     595     632 .. 0.85
   5 ?    1.2   0.0         1   5.3e+02       7      29 ..     688     710 ..     686     729 .. 0.75

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.55
     DUF1843   6 aiqqAiasGDLakMKalaaqaeqqLaeygdiasaleqL 43 
                 + + A+a GDL++  +  a  e   + ++ i ++++qL
  EEA20899.1 319 TVTTAVAHGDLSQKIESRAHGEI-FELQQTINTMVDQL 355
                 6789*******984333333333.25555666666666 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.59
     DUF1843   8 qqAiasGDLakMKalaaqaeqqLaeygd.iasaleqL 43 
                 ++A+a GDL +  ++ a+ +   ae ++ i s+++qL
  EEA20899.1 413 TKAVAKGDLTQ--KVQANCKGEIAELKNiINSMVDQL 447
                 68999999987..444444444555555235556655 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 1.6
     DUF1843   8 qqAiasGDLakMKalaaqaeqqLaeygdiasaleqL 43 
                 + A+a GDL + K +a    + L+ +  i  +++ L
  EEA20899.1 505 TTAVAKGDLTR-KVTANVQGEILDLKNTINDMVDRL 539
                 689******87.666666666666666666666655 PP

  == domain 4  score: 5.4 bits;  conditional E-value: 0.053
     DUF1843   8 qqAiasGDLakMKalaaqae 27 
                 +qAia GDL+k  +++aq e
  EEA20899.1 597 TQAIAKGDLSKKIEVHAQGE 616
                 79********9888888876 PP

  == domain 5  score: 1.2 bits;  conditional E-value: 1
     DUF1843   7 iqqAiasGDLakMKalaaqaeqq 29 
                 i++A+ +GD  k+ ++ a  e  
  EEA20899.1 688 ITDAATDGDFTKLITVNASGEMD 710
                 89*********999998887765 PP

>> DUF3829  Protein of unknown function (DUF3829)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.0     0.018       9.2     215     278 ..     292     355 ..     247     357 .. 0.86
   2 ?    5.0   0.3     0.028        15     215     278 ..     384     447 ..     371     449 .. 0.88
   3 ?   11.3   0.6   0.00034      0.17     186     280 .]     431     541 ..     423     541 .. 0.82
   4 ?    0.7   0.1      0.59     3e+02     215     277 ..     568     630 ..     558     633 .. 0.80
   5 ?    0.3   0.2      0.76   3.9e+02     188     277 ..     631     722 ..     604     725 .. 0.64
   6 ?    0.3   0.3      0.75   3.8e+02     214     238 ..     694     728 ..     651     755 .. 0.56

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.018
     DUF3829 215 kkpalesfkssakeflaaarkiirrirdkepysdsdkellksadsvegspeallrkynelidey 278
                  +  + +++++++ + +++++ +r+i++ +++  + +  +k+ +++ g   +l++ +n ++d+ 
  EEA20899.1 292 VHGIWKELTENVNIMAKNLTDQVREIATVTTAVAHGDLSQKIESRAHGEIFELQQTINTMVDQL 355
                 67899***********************9999888876666999*****************986 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.028
     DUF3829 215 kkpalesfkssakeflaaarkiirrirdkepysdsdkellksadsvegspeallrkynelidey 278
                  + ++++++ +++++  ++++ +r+i++ + +  + +  +k + + +g  ++l + +n+++d+ 
  EEA20899.1 384 VQGMWNELTVNVNAMANNLTTQVRDIANVTKAVAKGDLTQKVQANCKGEIAELKNIINSMVDQL 447
                 6789************************999988888777799******************986 PP

  == domain 3  score: 11.3 bits;  conditional E-value: 0.00034
     DUF3829 186 ldlaklkkklddlekaleklekaskeekr................kkpalesfkssakeflaaarkiirrirdkepysdsdkellksadsvegspeall 268
                  ++a+lk  ++ +  +l+++ +  ++ ++                 +  + +++++++ +  ++++ +r+i++ +++  + +  +k   +v+g   +l 
  EEA20899.1 431 GEIAELKNIINSMVDQLRQFAQEVTKIAKevgtdgvlggqatvhdVEGTWKDLTENVNRMANNLTTHVREIAEVTTAVAKGDLTRKVTANVQGEILDLK 529
                 667777777777777777775554444444777888888888999999*************************99999999877779999********* PP

     DUF3829 269 rkynelideyNs 280
                 + +n+++d+ N+
  EEA20899.1 530 NTINDMVDRLNK 541
                 *********995 PP

  == domain 4  score: 0.7 bits;  conditional E-value: 0.59
     DUF3829 215 kkpalesfkssakeflaaarkiirrirdkepysdsdkellksadsvegspeallrkynelide 277
                  + ++ +++++++++ +++++ +r i d + +  + +  +k+   ++g    l   +n+++d+
  EEA20899.1 568 VEGKWKDLTDNVNTMAQNLTSQVRGISDVTQAIAKGDLSKKIEVHAQGEILTLKVTINNMVDR 630
                 67899**********************988776666555558888888888888899999986 PP

  == domain 5  score: 0.3 bits;  conditional E-value: 0.76
     DUF3829 188 laklkkklddlekaleklekaskeekr...kkpalesfkssakeflaaarkiirrird.kepysdsdkellksadsvegspeallrkynelide 277
                 lak+ ++l+ +++++   ++++  +++       + +++++++++ +++++ +r   +  ++++d+d ++l +  +++g   +l rk+n++++ 
  EEA20899.1 631 LAKFATELKRVARDV-GVDGKMGGQANvegIAGRWKEITEDVNTMAENLTSQVRAFGEiTDAATDGDFTKL-ITVNASGEMDELKRKINKMVSN 722
                 555555555555553.3455555555555534467777788888777777777754331233344444444.6667899999999999999986 PP

  == domain 6  score: 0.3 bits;  conditional E-value: 0.75
     DUF3829 214 r..........kkpalesfkssakeflaaarkiir 238
                 +           + +++++k++++++++++r+ i+
  EEA20899.1 694 DgdftklitvnASGEMDELKRKINKMVSNLRDSIQ 728
                 22233333333445566666666666666666666 PP

>> Gp-FAR-1  Nematode fatty acid retinoid binding protein (Gp-FAR-1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0         8   4.1e+03      63     109 ..     251     297 ..     249     326 .. 0.71
   2 ?    3.9   0.0      0.12        62      50     109 ..     330     389 ..     291     408 .. 0.75
   3 ?    3.5   0.1      0.16        83      60     117 ..     432     489 ..     418     510 .. 0.79
   4 ?   -0.5   0.0       2.9   1.5e+03      53     113 ..     483     537 ..     479     555 .. 0.69
   5 ?    4.4   0.1     0.089        45      51     117 ..     573     633 ..     565     645 .. 0.74

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 8
    Gp-FAR-1  63 klkekvdkLspeakeFvkkliakgrkleaqvlagekpdlselkkvak 109
                 ++k+ ++++ ++ + F  +++  +r++ ++ + g + + + +  + k
  EEA20899.1 251 TFKRTINTMMDQLQVFGSEVSRVAREVGTEGILGGQAQITGVHGIWK 297
                 67888889999999999999988888888877777766555544444 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.12
    Gp-FAR-1  50 spaLyekaeklqaklkekvdkLspeakeFvkkliakgrkleaqvlagekpdlselkkvak 109
                 s ++ ++a     +l++ ++++ ++ ++F++++   +r + ++ + g + + + ++ + +
  EEA20899.1 330 SQKIESRAHGEIFELQQTINTMVDQLRTFATEVTRVARDVGTEGVLGGQAQIEGVQGMWN 389
                 66777888888899********************99999998888887777666655554 PP

  == domain 3  score: 3.5 bits;  conditional E-value: 0.16
    Gp-FAR-1  60 lqaklkekvdkLspeakeFvkkliakgrkleaqvlagekpdlselkkvaktifnkyks 117
                   a+lk+ ++++ ++ ++F++++ + ++++ ++ + g + + +++  + k+  ++ + 
  EEA20899.1 432 EIAELKNIINSMVDQLRQFAQEVTKIAKEVGTDGVLGGQATVHDVEGTWKDLTENVNR 489
                 55789999**********************9999999999988877666666655554 PP

  == domain 4  score: -0.5 bits;  conditional E-value: 2.9
    Gp-FAR-1  53 LyekaeklqaklkekvdkLspeakeFvkkliakgrkleaqvlagekpdlselkkvaktifn 113
                 L e+++++ ++l++ v ++ + + + +k+  +  rk+ a+ ++ge +d   lk+++++++ 
  EEA20899.1 483 LTENVNRMANNLTTHVREIAEVTTAVAKG--DLTRKVTAN-VQGEILD---LKNTINDMVD 537
                 77788888888888888888888877777..777777777.5666666...5555444444 PP

  == domain 5  score: 4.4 bits;  conditional E-value: 0.089
    Gp-FAR-1  51 paLyekaeklqaklkekvdkLspeakeFvkkliakgrkleaqvlagekpdlselkkvaktifnkyks 117
                   L  +++++ ++l+ +v ++s+ +++ +k+ ++k  +++aq   ge ++   lk+++++++    +
  EEA20899.1 573 KDLTDNVNTMAQNLTSQVRGISDVTQAIAKGDLSKKIEVHAQ---GEILT---LKVTINNMVDRLAK 633
                 578999********************9999966555555555...44444...66666666655555 PP

>> DUF4795  Domain of unknown function (DUF4795)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   1.8      0.29   1.5e+02      86     149 ..     245     359 ..     148     381 .. 0.68
   2 ?    7.1   0.3    0.0074       3.8      86     156 ..     384     458 ..     374     476 .. 0.83
   3 ?    5.3   0.6     0.027        14      85     147 ..     433     541 ..     413     560 .. 0.65
   4 ?    9.0   0.6    0.0019      0.99      67     149 ..     503     635 ..     470     654 .. 0.81
   5 ?   10.1   5.3   0.00089      0.46      20     170 ..     562     748 ..     562     753 .. 0.70

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.29
     DUF4795  86 fDeakkeLekmleellekle..........................eqeealkkaldtLq......................eelkekld...rlelep 133
                 +D  ++ +++ ++ ++++l+                          ++   +k++ ++++                       +l +k++   + e+ +
  EEA20899.1 245 MDPEIATFKRTINTMMDQLQvfgsevsrvarevgtegilggqaqitGVHGIWKELTENVNimaknltdqvreiatvttavahGDLSQKIEsraHGEIFE 343
                 666666666666666666666666666666666666777766666666666666666666777777777777778888887888888888888888888 PP

     DUF4795 134 Lkeqleerlkelqkel 149
                 L++ ++  +++l++  
  EEA20899.1 344 LQQTINTMVDQLRTFA 359
                 8888888887777554 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0074
     DUF4795  86 fDeakkeLekmleellekleeqeealkkaldtLq.eelkekld...rlelepLkeqleerlkelqkelqeameke 156
                 ++ + +eL+ +++ + + l+ q +++  + + +   +l++k+    + e+ +Lk+ +++ +++l++  qe ++  
  EEA20899.1 384 VQGMWNELTVNVNAMANNLTTQVRDIANVTKAVAkGDLTQKVQancKGEIAELKNIINSMVDQLRQFAQEVTKIA 458
                 6678888888999999999999999999999998679***************************97777654443 PP

  == domain 3  score: 5.3 bits;  conditional E-value: 0.027
     DUF4795  85 q......fDeakkeLekmleellek...............leeqeealkkaldtLq......................eelkekld...rlelepLkeq 137
                        + +++++L++ ++e+ +                ++ +e  +k + ++++                       +l+ k+    + e+ +Lk+ 
  EEA20899.1 433 IaelkniINSMVDQLRQFAQEVTKIakevgtdgvlggqatVHDVEGTWKDLTENVNrmannltthvreiaevttavakGDLTRKVTanvQGEILDLKNT 531
                 144444567777777777777777744555555555555555888888888888887777777777777666666666666666667777788888888 PP

     DUF4795 138 leerlkelqk 147
                 +++ ++ l+k
  EEA20899.1 532 INDMVDRLNK 541
                 8877777664 PP

  == domain 4  score: 9.0 bits;  conditional E-value: 0.0019
     DUF4795  67 elaekadkeaLatkvsrdqfDeakkeLekmleellekle..........................eqeealkkaldtLq.................... 119
                 e++ ++ k +L +kv   +++  + +L++ +++++++l+                          ++e ++k + d+++                    
  EEA20899.1 503 EVTTAVAKGDLTRKV-TANVQGEILDLKNTINDMVDRLNkfafevskvarevgtdgtlggqakvdNVEGKWKDLTDNVNtmaqnltsqvrgisdvtqai 600
                 556677788888888.88889999999999999999988888888888888888888888888889999***999999999999999999999999999 PP

     DUF4795 120 ..eelkekld...rlelepLkeqleerlkelqkel 149
                    +l +k++   + e+  Lk  +++ ++ l+k  
  EEA20899.1 601 akGDLSKKIEvhaQGEILTLKVTINNMVDRLAKFA 635
                 99999999999999999999999997777776543 PP

  == domain 5  score: 10.1 bits;  conditional E-value: 0.00089
     DUF4795  20 qeelekleekvkelekrledkekklealkkqieelekvkadkeeveeelaekadkeaLatkvsrdqfDeakkeLekml...................ee 99 
                 q++++++e+k k+l ++ ++  ++l +    i++  ++ a+  ++++++++ a  e L  kv  +++  +++++   l                   e 
  EEA20899.1 562 QAKVDNVEGKWKDLTDNVNTMAQNLTSQVRGISDVTQAIAK-GDLSKKIEVHAQGEILTLKVTINNMVDRLAKFATELkrvardvgvdgkmggqanvE- 658
                 57788999999999999999999999999999999988776.89******************666644444444444422223334443333333333. PP

     DUF4795 100 llekleeqeealkkaldtLq.........................eelkekldrlelepLkeqleerlkelqkelqeamekedkedeaaglrkkLl 170
                       +   ++k++ ++++                         ++l + +   e+++Lk ++++ + +l++ +q  +++++ +++a  ++ + l
  EEA20899.1 659 ------GIAGRWKEITEDVNtmaenltsqvrafgeitdaatdgdfTKLITVNASGEMDELKRKINKMVSNLRDSIQRNTAAREAAEQANRTKSEFL 748
                 ......55555555555555444444499988887777777755555555555***********************99888877778877777666 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.1       2.9   1.5e+03     101     119 ..     148     166 ..     138     178 .. 0.73
   2 ?    7.7   0.3    0.0073       3.8      34     114 ..     195     273 ..     174     278 .. 0.85
   3 ?    2.3   0.1      0.34   1.7e+02      51     108 ..     304     359 ..     289     369 .. 0.63
   4 ?    9.8   0.7    0.0017      0.87      49     116 ..     394     459 ..     379     463 .. 0.84
   5 ?    8.0   0.2    0.0058         3      48     106 ..     485     541 ..     470     553 .. 0.82
   6 ?    0.6   0.4       1.2     6e+02      49     106 ..     578     633 ..     562     645 .. 0.50
   7 ?    2.5   0.2       0.3   1.6e+02      24      66 ..     707     749 ..     702     798 .. 0.77

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 2.9
                 HHHHHHHHHHHHHHHHHHH CS
   Fib_alpha 101 esnirvLqnvlesneqkiq 119
                  +++r Lqn +e++ ++i+
  EEA20899.1 148 AETLRSLQNHVEKQAHEIS 166
                 5789999999999999986 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0073
                 CHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHH CS
   Fib_alpha  34 kkdlekleneleeisnstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvLqnvlesn 114
                 ++d+  l++el+++++ ++  ++  +ei  ++++  + +   +  ++    e++ ei+++k+ti++ + +++v  + +++ 
  EEA20899.1 195 HEDVGVLQRELRKHQQANEAFQKALREIGGIITQVANGDL--SMKVQIHPLEMDPEIATFKRTINTMMDQLQVFGSEVSRV 273
                 467888999*******************999987766665..78888899999999***************9987777665 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.34
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHH CS
   Fib_alpha  51 tkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvLq 108
                 +  a++l+ +++++ + + + ++    + +k++++   ei +l++ti++ + ++r   
  EEA20899.1 304 NIMAKNLTDQVREIATVTTAVAH--GDLSQKIESRAHGEIFELQQTINTMVDQLRTFA 359
                 33444555555555544444444..577777777777788888888888888877654 PP

  == domain 4  score: 9.8 bits;  conditional E-value: 0.0017
                 CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHH CS
   Fib_alpha  49 nstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvLqnvlesneq 116
                 n +  a++l+++++d+ + +++ +k    +++k++ +++ ei++lk+ i++ + ++r+  + + +  +
  EEA20899.1 394 NVNAMANNLTTQVRDIANVTKAVAK--GDLTQKVQANCKGEIAELKNIINSMVDQLRQFAQEVTKIAK 459
                 5667789999999999999999998..699**********************9999998887777665 PP

  == domain 5  score: 8.0 bits;  conditional E-value: 0.0058
                 CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHH CS
   Fib_alpha  48 snstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirv 106
                 +n ++ a++l+++++++ + + + +k    +++k++ +++ eil+lk+ti++ + ++++
  EEA20899.1 485 ENVNRMANNLTTHVREIAEVTTAVAK--GDLTRKVTANVQGEILDLKNTINDMVDRLNK 541
                 56778899999999999999999998..69*********************99988875 PP

  == domain 6  score: 0.6 bits;  conditional E-value: 1.2
                 CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHH CS
   Fib_alpha  49 nstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirv 106
                 n ++ a++l+++++ +   +q+ +k    + kk++ + + eil+lk ti++ + ++ +
  EEA20899.1 578 NVNTMAQNLTSQVRGISDVTQAIAK--GDLSKKIEVHAQGEILTLKVTINNMVDRLAK 633
                 2333344444444444444444444..3555555555556666666666666665554 PP

  == domain 7  score: 2.5 bits;  conditional E-value: 0.3
                 HCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH CS
   Fib_alpha  24 dlllkyekdvkkdlekleneleeisnstkeaeelvkeikdslr 66 
                 + +++ +++++k +++l++++++++   + ae+  ++ ++ l+
  EEA20899.1 707 GEMDELKRKINKMVSNLRDSIQRNTAAREAAEQANRTKSEFLA 749
                 5688888888888888888888888877777776655555554 PP

>> NOD  NOTCH protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.0     0.012       6.3       3      31 ..     228     256 ..     227     260 .. 0.86
   2 ?    3.9   0.0     0.078        40      21      38 ..     741     758 ..     736     760 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.012
         NOD   3 klaeGsLvlvVlidpeellnnskeFLrel 31 
                 ++a+G+L++ V+i+p e+  + ++F r +
  EEA20899.1 228 QVANGDLSMKVQIHPLEMDPEIATFKRTI 256
                 689***************99998886665 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.078
         NOD  21 lnnskeFLrelsalLrtn 38 
                  ++++eFL ++s+ +rt 
  EEA20899.1 741 NRTKSEFLANMSHEIRTP 758
                 578899**********95 PP

>> IcmF_C  Type VI secretion protein IcmF C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.1   0.00055      0.28      97     147 ..     209     257 ..     185     264 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00055
      IcmF_C  97 lglspaflkqfqraarirdalfa.gggepsvefeirplplsagvtelkleid 147
                  + ++af k++++   i  ++ +  +g++s++++i pl+++++++++k +i+
  EEA20899.1 209 QQANEAFQKALRE---IGGIITQvANGDLSMKVQIHPLEMDPEIATFKRTIN 257
                 3344444444444...5555566778*********************98876 PP

>> PA-IL  PA-IL-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.3      0.16        84      39      99 ..     379     438 ..     368     458 .. 0.77
   2 ?    8.3   0.1    0.0042       2.1      61     102 ..     493     533 ..     469     551 .. 0.82

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.16
                 STTBECECCCCSTTSS.S-TTTTCTCEEEEETTCEEEETTCEEEEEE-STTSBEEEEEEE- CS
       PA-IL  39 dqkegaagdrevpdqglipqdasiaalvakiankktiivntvlfktvapnnvdGelillyn 99 
                  q eg +g  +     + +    +++ v  ian   +++ + l + v   n +Ge+  l n
  EEA20899.1 379 AQIEGVQGMWNELTVNVNAMANNLTTQVRDIANVTKAVAKGDLTQKVQ-ANCKGEIAELKN 438
                 555555555444444455666778999********************9.899***987766 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.0042
                 TCTCEEEEETTCEEEETTCEEEEEE-STTSBEEEEEEE---T CS
       PA-IL  61 siaalvakiankktiivntvlfktvapnnvdGelillyndvp 102
                  +++ v  ia+  t+++ + l + v+  nv+Ge++ l n + 
  EEA20899.1 493 NLTTHVREIAEVTTAVAKGDLTRKVT-ANVQGEILDLKNTIN 533
                 5788999******************9.99*****98888764 PP

>> CMD  Carboxymuconolactone decarboxylase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.0     0.025        13      15      41 ..     306     330 ..     294     346 .. 0.79
   2 ?    1.7   0.0      0.54   2.7e+02       7      39 ..     480     512 ..     475     517 .. 0.78
   3 ?   -1.1   0.0       3.8   1.9e+03      27      69 ..    1205    1248 ..    1186    1252 .. 0.74

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.025
                 CCGSSTS-HHHHHHHHHHHHHHTT-HH CS
         CMD  15 lareggLdpkereLialavsaangcey 41 
                 +a ++ L+ + re++++++++a+g   
  EEA20899.1 306 MA-KN-LTDQVREIATVTTAVAHGDLS 330
                 43.55.*****************9765 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.54
                 HHHHHHHHCC.GSSTS-HHHHHHHHHHHHHHTT- CS
         CMD   7 ltalrealla.reggLdpkereLialavsaangc 39 
                 + +l e++     ++L+   re++ +++++a g 
  EEA20899.1 480 WKDLTENVNRmA-NNLTTHVREIAEVTTAVAKGD 512
                 666666666644.56****************986 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 3.8
                  HHHHHHHHHHTT.-HHHHHHHHHHHHHTT--HHHHHHHHHHHHH CS
         CMD   27 eLialavsaang.ceyCvdaHtraAleaGvteeeiaevlaqaaa 69  
                   +ial++ a++g +e C++a + + l + + +++  +++   a 
  EEA20899.1 1205 PIIALTAHAMLGdREKCIQAQMDEYLSKPLKQNQMIQTILKCAT 1248
                  47999999999989999999999988888888888877776665 PP

>> DUF2457  Protein of unknown function (DUF2457)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6  17.3   0.00043      0.22      57      91 ..      83     132 ..      58     143 .. 0.51

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00043
     DUF2457  57 e...............eddeedeeddddddddedddedddeedededdds 91 
                                 +dd++d+ ddddd+dd+d  eddd++d+++dd++
  EEA20899.1  83 YkrprrsrklkrkyddDDDDDDTGDDDDDEDDSDGSEDDDDDDNEDDDHA 132
                 34455555555555324444444444444455555555555554444333 PP

>> CENP-F_leu_zip  Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.1      0.68   3.5e+02      82     108 ..      55      81 ..      35      93 .. 0.87
   2 ?   -0.1   0.0       1.7   8.8e+02      53      81 ..     248     276 ..     244     278 .. 0.88
   3 ?    2.6   0.1      0.25   1.3e+02      50      78 ..     337     365 ..     297     370 .. 0.86
   4 ?    9.9   0.1    0.0013      0.68      53     123 ..     387     460 ..     378     465 .. 0.79
   5 ?    3.4   0.0      0.14        74      57     112 ..     483     541 ..     472     555 .. 0.53
   6 ?    1.9   0.1       0.4     2e+02      50      78 ..     613     641 ..     562     645 .. 0.68
   7 ?    6.0   0.2     0.021        11      18      66 ..     708     757 ..     704     796 .. 0.79

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.68
  CENP-F_leu_zip  82 keeLekelqkkqervseLeslnsslen 108
                     k+ L+ el+   +rv+eLe+  +s  n
      EEA20899.1  55 KKALTTELECLIRRVHELETELVSHPN 81 
                     889999999999999999998887665 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 1.7
  CENP-F_leu_zip  53 evetlkeeieelaeelreleldLvalrse 81 
                     e+ t+k  i+++  +l+ + ++++ + +e
      EEA20899.1 248 EIATFKRTINTMMDQLQVFGSEVSRVARE 276
                     78999**************9999988765 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.25
  CENP-F_leu_zip  50 skaevetlkeeieelaeelreleldLval 78 
                     +  e+ +l++ i+++  +lr + ++++ +
      EEA20899.1 337 AHGEIFELQQTINTMVDQLRTFATEVTRV 365
                     4569999**************99998876 PP

  == domain 4  score: 9.9 bits;  conditional E-value: 0.0013
  CENP-F_leu_zip  53 evetlkeeieelaeelreleldLvalrs..ekeeLekelqkk.qervseLeslnsslenlleekEqekvqmkee 123
                       ++l  +++ +a++l+    d++++++   k +L++++q + + ++ eL+++  s+  +l++  qe  ++ +e
      EEA20899.1 387 MWNELTVNVNAMANNLTTQVRDIANVTKavAKGDLTQKVQANcKGEIAELKNIINSMVDQLRQFAQEVTKIAKE 460
                     55678888999999999999999999953369999999997548899999999999999999988888777766 PP

  == domain 5  score: 3.4 bits;  conditional E-value: 0.14
  CENP-F_leu_zip  57 lkeeieelaeelreleldLvalr..sekeeLekelq.kkqervseLeslnsslenllee 112
                     l e+++++a++l+    ++++++    k +L++++  + q ++ +L+++  ++   l++
      EEA20899.1 483 LTENVNRMANNLTTHVREIAEVTtaVAKGDLTRKVTaNVQGEILDLKNTINDMVDRLNK 541
                     55555555555555555555554223455555555413455565555555555444433 PP

  == domain 6  score: 1.9 bits;  conditional E-value: 0.4
  CENP-F_leu_zip  50 skaevetlkeeieelaeelreleldLval 78 
                     ++ e+ tlk  i+++  +l ++ ++L+ +
      EEA20899.1 613 AQGEILTLKVTINNMVDRLAKFATELKRV 641
                     45678889999999999999999998876 PP

  == domain 7  score: 6.0 bits;  conditional E-value: 0.021
  CENP-F_leu_zip  18 kadsLkdkvenLerelemseenqekvileaEtskaevet.lkeeieelae 66 
                     + d Lk k++++ ++l +s + ++++   aE++  + ++ l ++ +e+++
      EEA20899.1 708 EMDELKRKINKMVSNLRDSIQRNTAAREAAEQANRTKSEfLANMSHEIRT 757
                     6799*****************99999999999877665525555555555 PP

>> GLE1  GLE1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.019       9.5      25     111 ..     250     336 ..     235     344 .. 0.75
   2 ?    3.8   0.1     0.057        29      18      95 ..     335     414 ..     328     418 .. 0.71
   3 ?    4.4   0.7     0.037        19       9      52 ..     420     461 ..     413     510 .. 0.80
   4 ?   -2.0   0.0       3.3   1.7e+03       5      58 ..     489     545 ..     485     602 .. 0.58
   5 ?   -1.7   0.1       2.6   1.3e+03      24      44 ..     709     729 ..     704     757 .. 0.69

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.019
        GLE1  25 gdlkrkInpkvgQltnsseqlkkitkel..kellesgkpvkvadk.pelaykyllnflAkalvsqaetevsakpeaAfplArvavgllse 111
                  + kr In+ + Ql+   ++++++++e+  + +l  + +++ +    ++ ++  +n++Ak+l +q+ + +++  ++A++ + +  ++ s+
  EEA20899.1 250 ATFKRTINTMMDQLQVFGSEVSRVAREVgtEGILGGQAQITGVHGiWKE-LTENVNIMAKNLTDQVREIATV--TTAVAHGDLSQKIESR 336
                 5789***********************9445688555555444335444.58889************99999..5566666666666555 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.057
        GLE1  18 kelkkllgdlkrkInpkvgQltnsseqlkkitkel..kellesgkpvkvadk..pelaykyllnflAkalvsqaetevsakp 95 
                 + +   +++l++ In+ v Ql++ +++++++++++  + +l  + +++ ++   +e  ++  +n +A++l  q+   + +++
  EEA20899.1 335 SRAHGEIFELQQTINTMVDQLRTFATEVTRVARDVgtEGVLGGQAQIEGVQGmwNE--LTVNVNAMANNLTTQVRDIANVTK 414
                 55667899************************998334566455554444445444..478888888888888776666555 PP

  == domain 3  score: 4.4 bits;  conditional E-value: 0.037
        GLE1   9 nlleqvkedkelkkllgdlkrkInpkvgQltnsseqlkkitkel 52 
                 +l ++v  +++ k  + +lk  In  v Ql++ +++++ki+ke+
  EEA20899.1 420 DLTQKV--QANCKGEIAELKNIINSMVDQLRQFAQEVTKIAKEV 461
                 566644..6779*****************************997 PP

  == domain 4  score: -2.0 bits;  conditional E-value: 3.3
        GLE1   5 qikknlleqvke..dkelkkllgdlkrkInpkv.gQltnsseqlkkitkelkelles 58 
                  + +nl + v e  + ++    gdl+rk++ +v g +   ++ +++++++l+++  +
  EEA20899.1 489 RMANNLTTHVREiaEVTTAVAKGDLTRKVTANVqGEILDLKNTINDMVDRLNKFAFE 545
                 555666666666555555666677778887777567777777777777777777622 PP

  == domain 5  score: -1.7 bits;  conditional E-value: 2.6
        GLE1  24 lgdlkrkInpkvgQltnsseq 44 
                 + +lkrkIn+ v+ l+ s + 
  EEA20899.1 709 MDELKRKINKMVSNLRDSIQR 729
                 567788888888877777633 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4  16.4   0.00025      0.13     640     677 ..      95     132 ..      75     184 .. 0.59
   2 ?   -3.7   0.1       4.4   2.2e+03     358     384 ..     715     742 ..     681     757 .. 0.53

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00025
  DNA_pol_phi 640 dededeeddeeeeeeddeededseedddeeesdedeed 677
                  + d+d++dd+  +++dde+d+d +eddd++++++d+  
   EEA20899.1  95 KYDDDDDDDDTGDDDDDEDDSDGSEDDDDDDNEDDDHA 132
                  33444444444444444444444433333333333332 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 4.4
  DNA_pol_phi 358 glkklvdllkslilssnee.sdekeaes 384
                  +++k+v +l++ i++++   ++ ++a++
   EEA20899.1 715 KINKMVSNLRDSIQRNTAArEAAEQANR 742
                  3445555555555552222334444444 PP

>> DUF1759  Protein of unknown function (DUF1759)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0     0.051        26      68     113 ..     328     373 ..     309     381 .. 0.87
   2 ?    2.3   0.1      0.28   1.4e+02      69     110 ..     421     462 ..     409     476 .. 0.85
   3 ?    1.2   0.0      0.62   3.2e+02      68     111 ..     512     555 ..     502     566 .. 0.87
   4 ?   -2.4   0.0       7.7     4e+03      70     110 ..     606     646 ..     577     654 .. 0.80

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.051
     DUF1759  68 dnkrkiirellnelmklpslkeedasqlrrivdavneivralealg 113
                 d ++ki +  + e+ +l+++ +  ++qlr++  +v ++ r + + g
  EEA20899.1 328 DLSQKIESRAHGEIFELQQTINTMVDQLRTFATEVTRVARDVGTEG 373
                 6678999999****************************99876655 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.28
     DUF1759  69 nkrkiirellnelmklpslkeedasqlrrivdavneivrale 110
                  ++k+ ++   e+ +l+++ ++ ++qlr++ ++v +i + + 
  EEA20899.1 421 LTQKVQANCKGEIAELKNIINSMVDQLRQFAQEVTKIAKEVG 462
                 56788888889999*****9*************999988765 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.62
     DUF1759  68 dnkrkiirellnelmklpslkeedasqlrrivdavneivralea 111
                 d +rk+ ++   e+ +l+++ ++ ++ l+++  +v ++ r + +
  EEA20899.1 512 DLTRKVTANVQGEILDLKNTINDMVDRLNKFAFEVSKVAREVGT 555
                 66899999999*********************999999998765 PP

  == domain 4  score: -2.4 bits;  conditional E-value: 7.7
     DUF1759  70 krkiirellnelmklpslkeedasqlrrivdavneivrale 110
                 ++ki  +   e+  l+ + ++ ++ l+++  ++ ++ r + 
  EEA20899.1 606 SKKIEVHAQGEILTLKVTINNMVDRLAKFATELKRVARDVG 646
                 66777777778888888888889999999999988888765 PP

>> Fez1  Fez1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0  12.1       1.9   9.8e+02      19     101 ..     151     231 ..     148     438 .. 0.85
   2 ?    6.0   3.2     0.029        15      10     140 ..     431     582 ..     417     755 .. 0.73

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 1.9
        Fez1  19 Lkdsqaevtqklseivalkaqlrelrakleekeeeikeleesleektlelevcenelqrkkseaellrekvekleeelkelre 101
                 L+  q+ v ++++ei   k  +  +r++l+ +ee+++++  ++   ++++ v++ el+++++ +e +++ ++++   ++++ +
  EEA20899.1 151 LRSLQNHVEKQAHEISIQKDIIARVREELDMQEERTRRTLVKV--EHEDVGVLQRELRKHQQANEAFQKALREIGGIITQVAN 231
                 999*******************************999877666..5678899********99999998887777666655544 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.029
        Fez1  10 GEislLKq.......QLkdsqaevtqklsei.....valkaqlrelrakleekeeeikeleesleektlelevcenelqrkkseaellrekvekleeel 96 
                 GEi+ LK+       QL++  +evt+ ++e+     +  +a++++++ + ++  e+++++ ++l+++ +e+ ++        ++ +l+r+ + +++ e+
  EEA20899.1 431 GEIAELKNiinsmvdQLRQFAQEVTKIAKEVgtdgvLGGQATVHDVEGTWKDLTENVNRMANNLTTHVREIAEVTTA----VAKGDLTRKVTANVQGEI 525
                 77777774444444489999999998888853333266677788888888888888888888888877776555444....445567777777788888 PP

        Fez1  97 kelreelselsleeeeaalesdeakaqrqe...............aeeleelkreverl 140
                  +l+++++++  + ++ a e ++  + r+                + + ++l+ +v+ +
  EEA20899.1 526 LDLKNTINDMVDRLNKFAFEVSK--VAREVgtdgtlggqakvdnvEGKWKDLTDNVNTM 582
                 88888888766555554433322..2222222233333222222222223333333333 PP

>> YL1  YL1 nuclear protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6  14.5     0.007       3.6      28     115 ..      96     177 ..      64     222 .. 0.53

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.007
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..x RF
         YL1  28 FaEeedDeefeseeeeeeeensDsdfdsdeedeesdeeedeeegekelerqerkkr...kkekkkrkaqkkkskkkkkkqkkkkkkkidp..q 115
                 + +++dD++  +++++e+    Dsd   +e+d+++d+e+d+ + +  l   +r+ r   +     r  q+ + k++   +++ +k  i++  +
  EEA20899.1  96 YDDDDDDDDTGDDDDDED----DSDG--SEDDDDDDNEDDDHAANGVLVTRRRTLRggaE---TLRSLQNHVEKQAH--EISIQKDIIARvrE 177
                 567777777776554443....5445..44444456888888888888888888885431...22222222222222..22223332222321 PP

>> AAA_13  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   1.7     0.092        47     357     471 ..     151     267 ..      55     278 .. 0.76
   2 ?   11.9   4.7   0.00012     0.062     290     446 ..     298     461 ..     295     496 .. 0.68
   3 ?    0.6   0.3      0.33   1.7e+02     377     470 ..     483     542 ..     468     554 .. 0.34
   4 ?    4.4   4.4     0.024        12     288     464 ..     572     766 ..     562     772 .. 0.51

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.092
      AAA_13 357 lesvkakiesikklvaeineliakhNekvanleeekeeakkklelhlveeleseldeykkkykklekaieklekelkeeeaelkkleeeikeLek..ql 453
                 l s+++ +e+  ++++  +++ia+  e  ++ ee++ +  +k+e+  v  l+ el + +++ ++++ka+ +    +++ ++    ++ +i  Le   ++
  EEA20899.1 151 LRSLQNHVEKQAHEISIQKDIIARVREELDMQEERTRRTLVKVEHEDVGVLQRELRKHQQANEAFQKALREIGGIITQVANGDLSMKVQIHPLEMdpEI 249
                 566666667777777777777777777777777777777777777777777777777777777777777777766666666666666666655532267 PP

      AAA_13 454 rdekpaaeeinkeLkafG 471
                  + k++++ + ++L+ fG
  EEA20899.1 250 ATFKRTINTMMDQLQVFG 267
                 777777777777777776 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 0.00012
      AAA_13 290 kliekveskkselleklkavsde.......asensafeedkeelkaeaealeeqLkglqralea...Krkepfksvelesvkakiesikklvaeineli 378
                 +l e+v+ + ++l++++ ++++        +  +++     + ++ e+ +l+++++++ ++l      +++++++v +e v +   +i+  +   nel 
  EEA20899.1 298 ELTENVNIMAKNLTDQVREIATVttavahgDLSQKI----ESRAHGEIFELQQTINTMVDQLRTfatEVTRVARDVGTEGVLGGQAQIEGVQGMWNELT 392
                 555666666666666666666552211111222222....2333334445555555544444430003456777888899999999************* PP

      AAA_13 379 akhNekvanleeekeeakkklelhlveeleseld.eykkkykklekaieklekelkeeeaelkkleeei 446
                  + N++ +nl++++ ++++  ++    +l+++++ + k ++++l++ i+++ ++l++ ++e+ k+++e+
  EEA20899.1 393 VNVNAMANNLTTQVRDIANVTKAVAKGDLTQKVQaNCKGEIAELKNIINSMVDQLRQFAQEVTKIAKEV 461
                 *******************999999999999999788999**********************9999995 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.33
      AAA_13 377 liakhNekvanleeekeeakkklelhlveeleseldeykkkykklekaieklekelkeeeaelkkleeeikeLekqlrdekpaaeeinkeLkaf 470
                 l ++ N++ +nl++ + e+++   +    +l+ ++                                   ++ + ++ d k++++++ + L++f
  EEA20899.1 483 LTENVNRMANNLTTHVREIAEVTTAVAKGDLTRKV----------------------------------TANVQGEILDLKNTINDMVDRLNKF 542
                 22222222222222222222222222222222222..................................2333333333333333333333333 PP

  == domain 4  score: 4.4 bits;  conditional E-value: 0.024
      AAA_13 288 LekliekveskkselleklkavsdeasensafeedkeelkaeaealeeqLkglqraleaKrkepfk.svelesvkaki.e...............sikk 369
                  ++l ++v+++ ++l+ ++  +sd  ++ +a  +  ++++ +a+     + +l+  +++ +++++k   el++v+ ++ +               + k+
  EEA20899.1 572 WKDLTDNVNTMAQNLTSQVRGISDVTQA-IAKGDLSKKIEVHAQGE---ILTLKVTINNMVDRLAKfATELKRVARDVgVdgkmggqanvegiagRWKE 666
                 5677788888888888888888776654.33333334443333322...33333333333333333223555555555313444444433344443333 PP

      AAA_13 370 lvaeineliakhNekvanleeekeeakk.klelhlveeleseldeyk....kkykklekaieklekelkeeeaelkkleeeikeLekqlrdekpaaeei 463
                 + +++n++ ++   +v  + e + +a++ ++ + +  ++  e+de+k    k +++l ++i+ ++++ +++e++ +++ e  +++  ++r++ +++  +
  EEA20899.1 667 ITEDVNTMAENLTSQVRAFGEITDAATDgDFTKLITVNASGEMDELKrkinKMVSNLRDSIQRNTAAREAAEQANRTKSEFLANMSHEIRTPMNGIIGM 765
                 333333333333333333333333333223444444666666666653333555667777777777777777777777777888888887777776655 PP

      AAA_13 464 n 464
                 +
  EEA20899.1 766 T 766
                 5 PP

>> BORCS6  BLOC-1-related complex sub-unit 6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.1       1.1   5.4e+02       5      42 ..     303     342 ..     295     372 .. 0.53
   2 ?    4.2   1.6     0.092        47      55      91 ..     470     506 ..     394     527 .. 0.61
   3 ?    5.0   0.1     0.051        26      58      90 ..     565     597 ..     511     607 .. 0.92
   4 ?   -1.0   0.0       3.7   1.9e+03      65      90 ..     664     689 ..     654     694 .. 0.80
   5 ?   -2.1   0.1         8   4.1e+03      77      88 ..     721     732 ..     708     811 .. 0.50

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 1.1
      BORCS6   5 thFvaedLeekiklsssvskkees..sslsesstpsasls 42 
                 ++ +a++L  +++  ++v++  +    s++ +s + ++++
  EEA20899.1 303 VNIMAKNLTDQVREIATVTTAVAHgdLSQKIESRAHGEIF 342
                 4456777777777766666655541233333344444444 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.092
      BORCS6  55 pnvlsdlereaqkvaasvdnllenlssklhsisaltv 91 
                 +  ++d+e   ++++++v+++ +nl++++++i+ +t 
  EEA20899.1 470 QATVHDVEGTWKDLTENVNRMANNLTTHVREIAEVTT 506
                 4568999999999999999999999999999988875 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.051
      BORCS6  58 lsdlereaqkvaasvdnllenlssklhsisalt 90 
                 ++++e + ++++++v+++ +nl+s+++ is +t
  EEA20899.1 565 VDNVEGKWKDLTDNVNTMAQNLTSQVRGISDVT 597
                 67899999*********************9988 PP

  == domain 4  score: -1.0 bits;  conditional E-value: 3.7
      BORCS6  65 aqkvaasvdnllenlssklhsisalt 90 
                  +++++ v+++ enl+s+++    +t
  EEA20899.1 664 WKEITEDVNTMAENLTSQVRAFGEIT 689
                 57899999999999999998776665 PP

  == domain 5  score: -2.1 bits;  conditional E-value: 8
      BORCS6  77 enlssklhsisa 88 
                 +nl+ ++++ +a
  EEA20899.1 721 SNLRDSIQRNTA 732
                 333333333332 PP

>> Mer2  Mer2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.4      0.22   1.1e+02      91     186 ..     151     244 ..     138     247 .. 0.69
   2 ?    6.6   3.4     0.012       5.9      48     190 ..     298     455 ..     296     459 .. 0.69
   3 ?    7.4   2.7    0.0066       3.4      48     140 ..     482     587 ..     475     591 .. 0.69
   4 ?   -0.6   7.6       1.9   9.8e+02      49     145 ..     575     684 ..     564     763 .. 0.42
   5 ?    1.7   0.0      0.39     2e+02      34      86 ..     767     815 ..     764     849 .. 0.74

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.22
        Mer2  91 ikdLsvkienqlsk..vskavldklkvkkhksntdtksnLtellekkeakileeidkkqtkleksvdttqelllnvnkQledvnevllSlskdlenls 186
                 ++ L+ ++e+q ++  ++k++  ++ ++   ++  t++ L+++  +    + +e++    k +++++  q+ l  ++  + +v +  lS++ +++ l+
  EEA20899.1 151 LRSLQNHVEKQAHEisIQKDIIARVREELDMQEERTRRTLVKVEHEDVGVLQRELR----KHQQANEAFQKALREIGGIITQVANGDLSMKVQIHPLE 244
                 55677777777665115677777777777777777777777766666666655555....55667777777787888877778777788887777765 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.012
        Mer2  48 kLinvlkenskeLlkvisklnellidlkeeesdnskekeikdlikdLsvkienqlskvskavldklk.............vkkhksntdtksnLtelle 133
                 +L++ ++ + k+L++ + ++   +  + +++  ++ e      i +L+ +i+   +++++  ++ +              + + +   +  ++Lt  ++
  EEA20899.1 298 ELTENVNIMAKNLTDQVREIATVTTAVAHGDLSQKIESRAHGEIFELQQTINTMVDQLRTFATEVTRvardvgtegvlggQAQIEGVQGMWNELTVNVN 396
                 678888888888888888888888888887777766666666666666666664333333222222233466667777653444444456678888888 PP

        Mer2 134 kkeakileeidk..kqtkleksvdttqelllnvnkQledvnevllSlskdlenlstrqt 190
                    ++++ ++++  + tk     d+tq++  n+   + ++++++ S+  +l++  +  t
  EEA20899.1 397 AMANNLTTQVRDiaNVTKAVAKGDLTQKVQANCKGEIAELKNIINSMVDQLRQFAQEVT 455
                 8888888888853356677777899***********************99998877655 PP

  == domain 3  score: 7.4 bits;  conditional E-value: 0.0066
        Mer2  48 kLinvlkenskeLlkvisklnellidlkeeesdnskekeikdlikdLsvkienqlskvskavldklk.............vkkhksntdtksnLtelle 133
                  L++ ++++ ++L++ + ++ e +  + +++  ++ + +++  i dL+ +i++  ++++k   +  k             + k ++  ++ ++Lt+ ++
  EEA20899.1 482 DLTENVNRMANNLTTHVREIAEVTTAVAKGDLTRKVTANVQGEILDLKNTINDMVDRLNKFAFEVSKvarevgtdgtlggQAKVDNVEGKWKDLTDNVN 580
                 6999***********************************************995544443322222222233334445553333333444455555555 PP

        Mer2 134 kkeakil 140
                    ++++
  EEA20899.1 581 TMAQNLT 587
                 5555555 PP

  == domain 4  score: -0.6 bits;  conditional E-value: 1.9
        Mer2  49 LinvlkenskeLlkvisklnellidlkeeesdnskekeikdlikdLsvkien...qlskvskavldklk...........vkkhksntdtksnLtelle 133
                 L+  ++ + ++L++ +  + + +  + +++  ++ e + +  i  L+v+i+n    l+k  ++++   +           + + +   +  +++te ++
  EEA20899.1 575 LTDNVNTMAQNLTSQVRGISDVTQAIAKGDLSKKIEVHAQGEILTLKVTINNmvdRLAKFATELKRV-ArdvgvdgkmggQANVEGIAGRWKEITEDVN 672
                 5666666666666666666666666666666555555555566666666666333122222221111.1233333333332222222233333333333 PP

        Mer2 134 kkeakileeidk 145
                    +++++++++
  EEA20899.1 673 TMAENLTSQVRA 684
                 333333333332 PP

  == domain 5  score: 1.7 bits;  conditional E-value: 0.39
        Mer2  34 KLELEsvdLrEksskLinvlkenskeLlkvisklnellidlkeeesdnskeke 86 
                  L L++ dL+    ++ nv+++  + Ll++i+++ ++  +++    ++  +++
  EEA20899.1 767 QLTLDTDDLKPYPREMLNVVHNLANSLLTIIDDILDIS-KIE---ANRMVIES 815
                 58899999***********************9988766.333...34444443 PP

>> DUF5593  Domain of unknown function (DUF5593)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.1       1.3   6.8e+02      22      55 ..     149     183 ..     142     205 .. 0.71
   2 ?   -0.0   0.0       2.8   1.5e+03      33      81 ..     245     293 ..     224     298 .. 0.82
   3 ?    4.5   0.1      0.11        57      33      83 ..     337     388 ..     315     391 .. 0.84
   4 ?    3.6   0.1      0.22   1.1e+02      35      81 ..     431     477 ..     409     482 .. 0.87

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 1.3
     DUF5593  22 kewtplasllrrkaalaav.rsaiaevvrsgepvs 55 
                   +++l++++ ++a+   + +++ia v++     +
  EEA20899.1 149 ETLRSLQNHVEKQAHEISIqKDIIARVREELDMQE 183
                 6789************9**5667777776554443 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 2.8
     DUF5593  33 rkaalaavrsaiaevvrsgepvsritpksdrviraepVlgpdgrvhgVq 81 
                   + +a+ ++ i++++++ +   +++++  r++ +e +lg + ++ gV+
  EEA20899.1 245 MDPEIATFKRTINTMMDQLQVFGSEVSRVAREVGTEGILGGQAQITGVH 293
                 456777788888899999888888888999999***********99998 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.11
     DUF5593  33 rkaalaavrsaiaevvrsgepvsritpksdrviraepVlgpdgrvhgVq.vW 83 
                 ++  + ++++ i+++v++ ++ ++++++  r + +e Vlg + ++ gVq +W
  EEA20899.1 337 AHGEIFELQQTINTMVDQLRTFATEVTRVARDVGTEGVLGGQAQIEGVQgMW 388
                 45556788999************999999999****************9555 PP

  == domain 4  score: 3.6 bits;  conditional E-value: 0.22
     DUF5593  35 aalaavrsaiaevvrsgepvsritpksdrviraepVlgpdgrvhgVq 81 
                   +a+++++i+++v++ ++ +++++k  +++ +  Vlg + +vh V+
  EEA20899.1 431 GEIAELKNIINSMVDQLRQFAQEVTKIAKEVGTDGVLGGQATVHDVE 477
                 4678999**************999999999**************985 PP

>> PPP4R2  PPP4R2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4  11.0     0.024        12     240     286 ..      84     130 ..      20     133 .. 0.62

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.024
      PPP4R2 240 eekdesvkveekdddeeddeedtdyveeeeddesedddeeeeeeeee 286
                 +    s+k++ k dd++dd+++ d +++e+d++  +dd+++++e+++
  EEA20899.1  84 KRPRRSRKLKRKYDDDDDDDDTGDDDDDEDDSDGSEDDDDDDNEDDD 130
                 34445555565555555555555544444444433333333333332 PP

>> RXT2_N  RXT2-like, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4  10.7     0.032        17      47      92 ..      87     133 ..      66     140 .. 0.38

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.032
      RXT2_N  47 ierskrkk......kekekeekeeeeedeegdeededdddeeeaeaaeenpy 92 
                 ++++k k+      +++++ +++++e+d++g+e+d+d     ++++++++  
  EEA20899.1  87 RRSRKLKRkyddddDDDDTGDDDDDEDDSDGSEDDDD-----DDNEDDDHAA 133
                 2222222233212122222222222222222222222.....3344444444 PP

>> Phage_Mu_Gam  Bacteriophage Mu Gam like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0       1.8   9.1e+02       5      59 ..     216     268 ..     202     272 .. 0.78
   2 ?    3.2   0.0      0.14        73      30      60 ..     331     361 ..     302     367 .. 0.88
   3 ?    5.4   0.3     0.031        16      30      62 ..     423     455 ..     407     517 .. 0.90
   4 ?   -1.2   0.0       3.3   1.7e+03       6      58 ..     489     543 ..     484     552 .. 0.69
   5 ?   -0.2   0.0       1.7   8.5e+02      30      62 ..     607     639 ..     572     644 .. 0.87
   6 ?    0.8   0.6       0.8   4.1e+02       7      45 ..     705     743 ..     703     754 .. 0.71

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 1.8
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH CS
  Phage_Mu_Gam   5 nwalrkiaelkreleeieaeaneeiaaikekleaeleplkkeieylesllkqYae 59 
                   ++alr+i+ + ++++     ++ +i  +  + + e+++ k  i+ + ++l+ +  
    EEA20899.1 216 QKALREIGGIITQVANGDLSMKVQIHPL--EMDPEIATFKRTINTMMDQLQVFGS 268
                   5677888888888777777777777665..5789999999999999999998865 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.14
                   HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHC CS
  Phage_Mu_Gam  30 aaikekleaeleplkkeieylesllkqYaea 60 
                   ++i+ ++  e+ +l++ i+ + ++l+++a++
    EEA20899.1 331 QKIESRAHGEIFELQQTINTMVDQLRTFATE 361
                   78999***********************987 PP

  == domain 3  score: 5.4 bits;  conditional E-value: 0.031
                   HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCTH CS
  Phage_Mu_Gam  30 aaikekleaeleplkkeieylesllkqYaeank 62 
                   ++++++ + e+++lk+ i+ + ++l+q+a++  
    EEA20899.1 423 QKVQANCKGEIAELKNIINSMVDQLRQFAQEVT 455
                   68899999*********************9865 PP

  == domain 4  score: -1.2 bits;  conditional E-value: 3.3
                   HHHHHHHHHHHHHHHHHHHHHHH..HHHHHHHHHHHCHHHHHHHHHHHHHHHHHH CS
  Phage_Mu_Gam   6 walrkiaelkreleeieaeanee..iaaikekleaeleplkkeieylesllkqYa 58 
                       ++  + re++e+ + + +     +++++ + e+  lk+ i+++ + l ++a
    EEA20899.1 489 RMANNLTTHVREIAEVTTAVAKGdlTRKVTANVQGEILDLKNTINDMVDRLNKFA 543
                   5555666666666666666654311566778888899999999999999988887 PP

  == domain 5  score: -0.2 bits;  conditional E-value: 1.7
                   HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCTH CS
  Phage_Mu_Gam  30 aaikekleaeleplkkeieylesllkqYaeank 62 
                   ++i+ +++ e+ +lk  i+ + + l ++a+++k
    EEA20899.1 607 KKIEVHAQGEILTLKVTINNMVDRLAKFATELK 639
                   57888999999999**************99998 PP

  == domain 6  score: 0.8 bits;  conditional E-value: 0.8
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH CS
  Phage_Mu_Gam   7 alrkiaelkreleeieaeaneeiaaikekleaeleplkk 45 
                   a +++ elkr+++++ + + ++i++ +++ ea+ ++  +
    EEA20899.1 705 ASGEMDELKRKINKMVSNLRDSIQRNTAAREAAEQANRT 743
                   567888999999999999999998877666655444444 PP

>> SpoIIID  Stage III sporulation protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0      0.37   1.9e+02      36      65 ..     295     324 ..     286     328 .. 0.85
   2 ?   -0.6   0.1       2.9   1.5e+03      39      64 ..     390     415 ..     386     428 .. 0.83
   3 ?    4.4   0.2     0.078        40      37      62 ..     480     505 ..     437     520 .. 0.82
   4 ?   -1.5   0.0       5.4   2.8e+03      33      58 ..     529     553 ..     503     557 .. 0.79
   5 ?    2.3   0.0      0.36   1.9e+02      38      64 ..     573     599 ..     560     603 .. 0.91

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.37
     SpoIIID  36 vhkDvterLkkinkklakqvkevLeknkae 65 
                 + k++te ++ + k+l +qv+e+  +  a 
  EEA20899.1 295 IWKELTENVNIMAKNLTDQVREIATVTTAV 324
                 789*******************98776665 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 2.9
     SpoIIID  39 DvterLkkinkklakqvkevLeknka 64 
                 ++t  ++ + ++l +qv+++ ++ ka
  EEA20899.1 390 ELTVNVNAMANNLTTQVRDIANVTKA 415
                 67778888899999999999999887 PP

  == domain 3  score: 4.4 bits;  conditional E-value: 0.078
     SpoIIID  37 hkDvterLkkinkklakqvkevLekn 62 
                  kD+te ++++ ++l ++v+e+ e+ 
  EEA20899.1 480 WKDLTENVNRMANNLTTHVREIAEVT 505
                 39********************9876 PP

  == domain 4  score: -1.5 bits;  conditional E-value: 5.4
     SpoIIID  33 kstvhkDvterLkkinkklakqvkev 58 
                 k t+ +D+ +rL+k   ++ k  +ev
  EEA20899.1 529 KNTI-NDMVDRLNKFAFEVSKVAREV 553
                 5555.699999999998888877776 PP

  == domain 5  score: 2.3 bits;  conditional E-value: 0.36
     SpoIIID  38 kDvterLkkinkklakqvkevLeknka 64 
                 kD+t+ ++++ ++l +qv+ + ++ +a
  EEA20899.1 573 KDLTDNVNTMAQNLTSQVRGISDVTQA 599
                 9******************99988766 PP

>> RNA_pol_3_Rpc31  DNA-directed RNA polymerase III subunit Rpc31
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2  14.3    0.0053       2.7     170     214 ..      88     130 ..      34     134 .. 0.66

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0053
  RNA_pol_3_Rpc31 170 lleklkelaeeeddeeekkekedeeeeeeeeeddefddddedggD 214
                        +klk++ +++dd++++ + +d+e++++  edd+ dd   +++D
       EEA20899.1  88 RSRKLKRKYDDDDDDDDTGDDDDDEDDSDGSEDDDDDDN--EDDD 130
                      457888766666664333333333333233333333322..3555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1319 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1732  (0.0966033); expected 358.6 (0.02)
Passed bias filter:                      851  (0.047465); expected 358.6 (0.02)
Passed Vit filter:                       137  (0.00764125); expected 17.9 (0.001)
Passed Fwd filter:                        58  (0.00323498); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              35  [number of targets reported over threshold]
# CPU time: 1.57u 0.40s 00:00:01.97 Elapsed: 00:00:00.56
# Mc/sec: 7037.24
//
Query:       EEA20900.1  [L=520]
Description: phenylalanyl-tRNA synthetase beta chain cytoplasmic [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-86  290.1   0.0    1.7e-86  289.7   0.0    1.2  1  tRNA-synt_2d     tRNA synthetases class II core domain (F)
    3.8e-16   59.1   0.2    1.1e-15   57.7   0.2    1.8  1  PheRS_DBD3       PheRS DNA binding domain 3
    3.9e-07   29.7   0.0     0.0027   17.2   0.0    2.5  3  tRNA_synthFbeta  Phenylalanyl tRNA synthetase beta chain CLM 
    5.2e-05   22.5   0.1     0.0031   16.6   0.0    2.9  3  tRNA-synt_2      tRNA synthetases class II (D, K and N)
    0.00019   21.3   0.3    0.00055   19.9   0.3    1.8  1  PheRS_DBD2       PheRS DNA binding domain 2


Domain annotation for each model (and alignments):
>> tRNA-synt_2d  tRNA synthetases class II core domain (F)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  289.7   0.0   4.7e-90   1.7e-86       2     243 ..     205     510 ..     204     512 .. 0.97

  Alignments for each domain:
  == domain 1  score: 289.7 bits;  conditional E-value: 4.7e-90
                   .-TSSCTSCTSHSB-SHHHHHHHHHHHHHHCTTCEESS.TTSEEEHHHHTSTTTSTTTSHHHCHTTSEBTCTSSS-..................... CS
  tRNA-synt_2d   2 idvtlpgkrieagklhpltkvleeikeiflelgfeeve.gpevesefynfdaLnvpqdhpaRdmqdtFylkkpeka..................... 76 
                   ++++ +g+ + +g+lhpl+kv++e+++if+e+gfee+  ++ ve+ f+nfdaL vpq+hpaRd+qdtFy+ +p ka                     
    EEA20900.1 205 YNFNSKGALTPSGALHPLNKVRQEFRNIFFEMGFEEMPtNRFVETGFWNFDALYVPQQHPARDLQDTFYIADPLKAdppredppndphltkassmps 301
                   89999999*****************************9999*********************************99********************* PP

                   ........................................ECESEEE-SSTHHHHHHHH...TTS-SSEEEEEEEEEEBSST-SSSB-SEEEEEEEE CS
  tRNA-synt_2d  77 ........................................veekllLRthttavqirtl...ekkkppikiisigrvfRrdavDathlaeFhqvegl 130
                                                           ++ +l+LRthtt+v+  +l   +++  p++++si+rvfR++avDathlaeFhqveg+
    EEA20900.1 302 sakkqedkpldykqywdnvravhehgkygsigyrypwnpdEALRLVLRTHTTSVSTYMLhklAANPRPARYFSIDRVFRNEAVDATHLAEFHQVEGV 398
                   ****************************************999************999988788899****************************** PP

                   EEETT--HHHHHHHHHHHHHHHCTSTEEEEEEECEETTEEEEEEEEEEECCSSSSEEEEEEEEEE-HHHHHHTT-.TTSEEEEEEEEHHHHHHHHHT CS
  tRNA-synt_2d 131 vvdenvsladlkgvleellkklfgaevkvrfrpsyfpftePsaevdvylvekkkkwlEllgaGmvrpevleavgideevsgfafGlGveRlamlkyg 227
                   ++d ++ l  l+g++e ++ k+ g + ++rf+p+++p+tePs+e++ y+ +  +kw+E++++Gm+rpe+le++g++++++++++Gl++eR +m+kyg
    EEA20900.1 399 IADFGLALGGLIGFMEVFFAKM-GIH-RLRFKPAFNPYTEPSMEIFGYH-DGLGKWVEIGNSGMFRPEMLESMGLPKDMRVYGWGLSLERPTMIKYG 492
                   **********************.**9.**********************.9********************************************** PP

                   -SSGHHHHTT...HHHHG CS
  tRNA-synt_2d 228 ieDiRelven..dlrflr 243
                   +++iRel+ +  dl+f++
    EEA20900.1 493 VSNIRELLGHkvDLNFIE 510
                   *******99967888776 PP

>> PheRS_DBD3  PheRS DNA binding domain 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.7   0.2     3e-19   1.1e-15       1      58 [.      71     127 ..      71     128 .. 0.83

  Alignments for each domain:
  == domain 1  score: 57.7 bits;  conditional E-value: 3e-19
  PheRS_DBD3   1 ShEarvfaavpp..eggisqkel.kklggdpvakiGfskAmknkWikkdkgdgkvvrkvds 58 
                 ShEa+vf+av +  +g +++++l + +g+  +ak+G+++A+k +Wikkdk+  ++ +++d+
  EEA20900.1  71 SHEAKVFEAVLAslDG-LKIADLpAIVGK-DIAKVGQGNAFKRGWIKKDKD--LLRANTDK 127
                 9*********977776.******555555.79****************874..47777666 PP

>> tRNA_synthFbeta  Phenylalanyl tRNA synthetase beta chain CLM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.1   0.0       2.4   8.6e+03     141     163 ..      29      50 ..      28      57 .. 0.78
   2 !    9.9   0.0   0.00013      0.46      10      45 ..     214     249 ..     210     282 .. 0.85
   3 !   17.2   0.0   7.5e-07    0.0027      85     209 ..     359     478 ..     339     483 .. 0.80

  Alignments for each domain:
  == domain 1  score: -4.1 bits;  conditional E-value: 2.4
  tRNA_synthFbeta 141 vdfydlkgivealleslgiekve 163
                      v f ++k+++++l+++  + ++e
       EEA20900.1  29 VPFLNIKAALDRLASRSMV-EYE 50 
                      5689999999999998888.554 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.00013
  tRNA_synthFbeta  10 ttegelnkeqklrrklrdllagaGlnEvitysfvse 45 
                      t+ g+l++ +k+r++ r++  ++G+ E+ t  fv  
       EEA20900.1 214 TPSGALHPLNKVRQEFRNIFFEMGFEEMPTNRFVET 249
                      667889***************************975 PP

  == domain 3  score: 17.2 bits;  conditional E-value: 7.5e-07
  tRNA_synthFbeta  85 vlarNlargnedvrlFEigkvflkd.seeelpeeerhlaivltgkreeeswsekaravdfydlkgivealleslgiekvefepaehpalhpgrs 177
                       l +  a+  +  r F i +vf+++  + +  +e +++ +v++                   l g++e +++++gi +++f+pa +p+ +p   
       EEA20900.1 359 MLHKLAANPRP-ARYFSIDRVFRNEaVDATHLAEFHQVEGVIADFG-----------LALGGLIGFMEVFFAKMGIHRLRFKPAFNPYTEPSME 440
                      44444445555.999**********9888999**********9999...........999*******************************766 PP

  tRNA_synthFbeta 178 Aeikvdgk....evGvlGelhpevleafdlkq..rvyv 209
                         + dg     e+G  G + pe+le+++l++  rvy+
       EEA20900.1 441 IFGYHDGLgkwvEIGNSGMFRPEMLESMGLPKdmRVYG 478
                      655666546677*******************9666665 PP

>> tRNA-synt_2  tRNA synthetases class II (D, K and N)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0     0.064   2.3e+02      26      46 ..     223     243 ..     215     258 .. 0.87
   2 !   16.6   0.0   8.7e-07    0.0031      91     119 ..     369     396 ..     353     419 .. 0.84
   3 ?    0.8   0.0     0.059   2.1e+02     286     307 ..     478     499 ..     466     502 .. 0.92

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.064
                  HHHHHHHHHHHHHTT-EE--- CS
                  xxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2  26 stvtkavrkyleengfieiet 46 
                  ++v + +r++++e gf e+ t
   EEA20900.1 223 NKVRQEFRNIFFEMGFEEMPT 243
                  7899************99877 PP

  == domain 2  score: 16.6 bits;  conditional E-value: 8.7e-07
                  HSEEEEEEEEE--S--BTTB-S-CEEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2  91 idrvfqiaraFRaEdsrtdrhlaEFtqie 119
                    r+f+i r+FR+E ++++ hlaEF q+e
   EEA20900.1 369 PARYFSIDRVFRNEAVDAT-HLAEFHQVE 396
                  579**************77.566*****9 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.059
                  EEEEEHHHHHHHHCT-SSGGGC CS
                  xxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2 286 GlglGldRlvmlllgsesIrdv 307
                  G+gl+l+R +m+  g ++Ir++
   EEA20900.1 478 GWGLSLERPTMIKYGVSNIREL 499
                  9*******************97 PP

>> PheRS_DBD2  PheRS DNA binding domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   0.3   1.5e-07   0.00055       1      33 []     130     161 ..     130     161 .. 0.79

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 1.5e-07
  PheRS_DBD2   1 DeVqekLkliqeGkadelddkeknELKKRKLlq 33 
                 De++  L+ i+e +    d+k+ ++LKKRKL++
  EEA20900.1 130 DETRLLLQTIKESQTH-PDPKVIADLKKRKLIA 161
                 6667777777777666.699***********95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (520 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       488  (0.0272185); expected 358.6 (0.02)
Passed bias filter:                      450  (0.025099); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3668.18
//
Query:       EEA20901.1  [L=86]
Description: 40S ribosomal protein S21 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.7e-40  136.4   0.0      3e-40  136.2   0.0    1.0  1  Ribosomal_S21e  Ribosomal protein S21e


Domain annotation for each model (and alignments):
>> Ribosomal_S21e  Ribosomal protein S21e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  136.2   0.0   1.7e-44     3e-40       1      79 []       1      79 [.       1      79 [. 0.99

  Alignments for each domain:
  == domain 1  score: 136.2 bits;  conditional E-value: 1.7e-44
  Ribosomal_S21e  1 mqndagelVdlYiPrkcsatnrlItakDhasvqinvaevdetGratgesttyalsgairrkGesddslnrlakkdgllk 79
                    m+n++ge+VdlY+Prkcsatnr+I+a+Dhasvqi++++vde+Gr+tge+ +yalsg++r++Ge+ddslnrla++dg+lk
      EEA20901.1  1 MENEKGEIVDLYVPRKCSATNRIIKANDHASVQISIGNVDENGRYTGENGVYALSGFVRARGEADDSLNRLAQRDGYLK 79
                    9**************************************************************************9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (86 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       269  (0.0150036); expected 358.6 (0.02)
Passed bias filter:                      237  (0.0132188); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.29s 00:00:00.69 Elapsed: 00:00:00.45
# Mc/sec: 578.52
//
Query:       EEA20902.1  [L=410]
Description: NUDIX family hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.3e-07   29.1   0.0    2.1e-06   27.8   0.0    1.7  1  NUDIX     NUDIX domain


Domain annotation for each model (and alignments):
>> NUDIX  NUDIX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0   1.2e-10   2.1e-06       3     117 ..      84     224 ..      82     236 .. 0.72

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 1.2e-10
                 EEEEEEEEEETTSEEEEEEESSSSTTT....EESSEEECBT..................TSHHHHHHHHHHHHHHSE...EE.EEEEEEEEEEEEEEEE CS
       NUDIX   3 rravgvvllnekgevLlvrrskkpfpg....WelPgGkvep..................gEtpeeAArREleEEtGl...ea.ellellgrlhylapyd 75 
                 r++ +vvl+ +++evLl++r  k+ ++      +PgG +                    g +++ AA+REl+EE G+   +   + + l ++++   ++
  EEA20902.1  84 RPSSSVVLISPENEVLLLHRV-KTSTSfasaHVFPGGNISVrqdgeftvsledprrhydGINYRRAAIRELFEESGIllaTDtTNPQKLVHVDEAERER 181
                 78899**999999********.44444333446*******999***************555***************63342224446666677777777 PP

                 EEEEEEEEEEEEEEEEECSGCSST..STTTEEEE.EEEEHHHHHH CS
       NUDIX  76 gpygdeheilyvfleevegelepn..denevsev.rwvpleellk 117
                 g+y+  h   + f+e ++ ++ +   d++ +  +  w+++  l +
  EEA20902.1 182 GRYD-IHNNKIGFEEWLKKQNSTAemDTDNLIPFtHWITPPNL-P 224
                 7777.77777888855555555554444444444358877777.4 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (410 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       514  (0.0286686); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2768.55
//
Query:       EEA20903.1  [L=545]
Description: IMP dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   3.9e-128  427.3   3.3   4.6e-128  427.1   3.3    1.0  1  IMPDH         IMP dehydrogenase / GMP reductase domain
    2.1e-19   69.7   0.1    1.4e-10   41.4   0.0    2.6  2  CBS           CBS domain
    8.9e-07   28.2   0.6      9e-06   24.9   0.5    2.3  2  FMN_dh        FMN-dependent dehydrogenase
    1.6e-05   24.4   6.3      0.021   14.2   5.7    2.7  2  NMO           Nitronate monooxygenase
     0.0002   20.9   0.9    0.00051   19.6   0.9    1.6  1  His_biosynth  Histidine biosynthesis protein
     0.0025   17.3   0.8      0.011   15.2   0.1    2.1  2  Aldolase      KDPG and KHG aldolase
  ------ inclusion threshold ------
      0.011   15.7   0.0       0.02   14.9   0.0    1.3  1  YpsA          YspA SLOG family
      0.036   13.0   0.0       0.06   12.2   0.0    1.3  1  PK            Pyruvate kinase, barrel domain
      0.092   12.0   1.2       0.22   10.8   0.5    1.8  2  ThiG          Thiazole biosynthesis protein ThiG
       0.16   11.5   0.0       0.43   10.1   0.0    1.7  2  SHNi-TPR      SHNi-TPR


Domain annotation for each model (and alignments):
>> IMPDH  IMP dehydrogenase / GMP reductase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  427.1   3.3  2.5e-131  4.6e-128       1     345 []      49     534 ..      49     534 .. 0.96

  Alignments for each domain:
  == domain 1  score: 427.1 bits;  conditional E-value: 2.5e-131
                 E--GGGEEEE---B-S-GGGSB--EESSTTEEESSSEEE-SSTTT-SHHHHHHHHHTTSEEEE-SSS-HHHHHHHHHHHHTS................. CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................. RF
       IMPDH   1 gltfddvllvpaksevlpkevdlktkltkkiklniPlvsaamdtvtesemAialareGgigvihknlsieeqaeevkkvkrs................. 82 
                 +lt++d+l++p+++ + +++v+l+t +tk+i+l+ Pl+s++mdtvte++mAi++a  Gg+gvih+n+s+e+qae+v+kvkr+                 
  EEA20903.1  49 ALTYNDFLILPGYIGFPASDVTLDTPVTKRISLKAPLLSSPMDTVTEHNMAIHMALLGGLGVIHHNCSAEDQAEMVRKVKRYengfildpvvispkttv 147
                 69************************************************************************************************* PP

                 ................................................................................................... CS
                 ................................................................................................... RF
       IMPDH  83 ................................................................................................... 82 
                                                                                                                    
  EEA20903.1 148 aeakelkstwgfggfpvtengtlrsklvgivtsrdiqfhtsdedpvtevmstdlvtapagttlaeanevlrnskkgklpivdkdgnlvsllsrsdlrkn 246
                 *************************************************************************************************** PP

                 ...TTSXBX.TTSXB-EEEEE-SSTTHHHHHHHHHHTT-SEEEEE-STSSSHHHHHHHHHHHHHTTTSEEEEEEE-SHHHHHHHHHTT-SEEEE-SS-S CS
                 ...xxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       IMPDH  83 ...pnaakd.ekgrllvgaavgvkedalervkalveagvdvlvvdsahghsekvleavkeikkkveeveviaGnvataegakaLieagadavkvGiGpG 177
                    p a+k  ++++l+ +aa+g++e+++er+++lv+ag+d++++ds++g+s ++l+++k+ikk++++++viaGnv+t+e+a++Li+agad++++G+G+G
  EEA20903.1 247 lhyPLASKLpHSKQLIAAAAIGTRESDKERLQMLVDAGLDIVILDSSQGNSMYQLDMIKYIKKTYPQIDVIAGNVVTREQAANLIAAGADGLRIGMGSG 345
                 ***88888549999************************************************************************************* PP

                 TTBHHHHHCSB---HHHHHHHHHHHHCTCT-EEEEES---SHHHHHHHHHTT-SEEEESCCCTTBTTSSSEEEEET.TEEEEEEEETTSHHHHHH.... CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxx.... RF
       IMPDH 178 siCttrvvagvGvpqltAvaevaeaakkagvpviaDGGikysgdivkAlaaGadavmlGsllagteEspgevilie.grkyKeyrGmgslgamkk.... 271
                 s C+t++v++vG+pq+ +v +va++a+++gvp+iaDGGi++ g+ivk la+Ga+++m+G llagt+Espg++++ + g+ +K+yrGmgs++am++    
  EEA20903.1 346 SACITQEVMAVGRPQALSVRSVASFAARFGVPCIADGGIQNVGHIVKGLAMGASTIMMGGLLAGTTESPGDYFVSSeGQLVKAYRGMGSIDAMEDkkag 444
                 ************************************************************************98776****************444688 PP

                 ..........-SS-TTS-...--SS-SBEEEEEE--B-HHHHHHHHHHHHHHHHHHHT-SSHHHHHH.....H-EEEEE-HHHHHHHS-- CS
                 ..........xxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxx RF
       IMPDH 272 ..........gskdryfq.kkeklvpeGvegrvpykgsvkevveqlvgglrsgmgylGaktieelke.....kakfvritaaglkeshvH 345
                             + ryf+ k++ lv++Gv+g+v ++gsv+++v +l++g++++++++G++++++l+e     +++f+ ++ ++++e++vH
  EEA20903.1 445 kggkdskasnAGTARYFSeKDRVLVAQGVSGSVLDRGSVTKFVPYLIAGIQHSLQDIGVRSVKDLHEsvnnkTVRFELRSGSAQAEGNVH 534
                 8887765543255699984466********************************************988888899**************9 PP

>> CBS  CBS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   0.0     6e-09   1.1e-05       8      51 ..     137     183 ..     121     186 .. 0.88
   2 !   41.4   0.0   7.9e-14   1.4e-10       1      56 [.     193     248 ..     193     249 .. 0.94

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 6e-09
                 SCEEEETTSBHHHHHHHHHHHT..SSEEEEEETTT....BEEEEEEHHHH CS
         CBS   8 dvvtvppdttleealelmrekg..vsrlPVVdedg....klvGivtlrDl 51 
                 d+v+++p tt++ea el   +   ++++PV+ e+g    klvGivt rD+
  EEA20903.1 137 DPVVISPKTTVAEAKELK--STwgFGGFPVT-ENGtlrsKLVGIVTSRDI 183
                 799**************6..3346*******.89988777*********9 PP

  == domain 2  score: 41.4 bits;  conditional E-value: 7.9e-14
                 HHHHSBSSCEEEETTSBHHHHHHHHHHHTSSEEEEEETTTBEEEEEEHHHHHHHHH CS
         CBS   1 VgdimtrdvvtvppdttleealelmrekgvsrlPVVdedgklvGivtlrDllrall 56 
                 V+++m++d+vt+p  ttl+ea e +r+++ + lP+Vd+dg+lv +++++Dl + l+
  EEA20903.1 193 VTEVMSTDLVTAPAGTTLAEANEVLRNSKKGKLPIVDKDGNLVSLLSRSDLRKNLH 248
                 789**********************976679********************99876 PP

>> FMN_dh  FMN-dependent dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.9   0.5     5e-09     9e-06     193     302 ..     289     406 ..     232     414 .. 0.66
   2 ?    0.4   0.0      0.14   2.6e+02     313     345 ..     481     513 ..     467     516 .. 0.86

  Alignments for each domain:
  == domain 1  score: 24.9 bits;  conditional E-value: 5e-09
                 HHCCCHB-TC--HHHHHHHHHHHS.SEEEEEEE-SHHHHHHHHHTTESEEEE--GGG.......TSSTT---HHHCHHHHHHHH...SS-EEEESS--S CS
      FMN_dh 193 efvgkqldpsltwddikwlreqtk.lplvvKGvltaedakraveaGvdgivvSNHGG.......RqldgapatidvLpeiveavgg.rievlvDgGirr 282
                  + ++q ++  + d ik ++++ + + ++   v+t e a ++++aG+dg+ +    G           g p +++v  +++  +++  ++ ++DgGi++
  EEA20903.1 289 ILDSSQGNSMYQLDMIKYIKKTYPqIDVIAGNVVTREQAANLIAAGADGLRIGMGSGsacitqeVMAVGRPQALSV-RSVASFAARfGVPCIADGGIQN 386
                 3344455667789999***9998747899999********************999996666532111222222222.333333332359********** PP

                 HHHHHHHHHTT-SEEEESHH CS
      FMN_dh 283 GsDvlkAlalGAdavllGRp 302
                   +++k la+GA+ +++G  
  EEA20903.1 387 VGHIVKGLAMGASTIMMGGL 406
                 *****************975 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.14
                 HHHHHHHHHHHHHHHHHHHHHT-SBHHHHHCGG CS
      FMN_dh 313 eGvervleilraelertmallGvksvaeldrsl 345
                   v++ +  l a ++++++ +Gv+sv++l++s+
  EEA20903.1 481 GSVTKFVPYLIAGIQHSLQDIGVRSVKDLHESV 513
                 568899999999*****************9885 PP

>> NMO  Nitronate monooxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.7   0.0    0.0012       2.1       3      59 ..      74     129 ..      72     158 .. 0.84
   2 !   14.2   5.7   1.2e-05     0.021     135     233 ..     313     415 ..     245     423 .. 0.62

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0012
         NMO   3 lltellkikppvvqpgmggiskarLaaavsnaGgLGvlasgyltaDrlakeirkvka 59 
                 ++t+ +  k p+  ++m  +++ ++a   +  GgLGv+     +    a+ +rkvk+
  EEA20903.1  74 PVTKRISLKAPLLSSPMDTVTEHNMAIHMALLGGLGVIHHNCSAE-DQAEMVRKVKR 129
                 567778899*****************************9555555.45667788876 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 1.2e-05
         NMO 135 agvvliptissvkearkvearGaDalivqGpeaGGhqG...tpevgdkglfaLvpqvldavd...iPviAaGGiidrrgvaaaLalGAsgvqigtrfLl 227
                  + v+ + + + ++a  ++a+GaD l + G+ +G        ++vg   +   v +v++  +   +P iA GGi +   +   La+GAs + +g  + +
  EEA20903.1 313 QIDVIAGNVVTREQAANLIAAGADGLRI-GMGSGSACItqeVMAVGR-PQALSVRSVASFAArfgVPCIADGGIQNVGHIVKGLAMGASTIMMGGLLAG 409
                 3445556667778888899999998854.555555444123444443.22333344444433688********************************** PP

         NMO 228 tkesda 233
                 t es+ 
  EEA20903.1 410 TTESPG 415
                 ***975 PP

>> His_biosynth  Histidine biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.9   2.9e-07   0.00051      84     223 ..     273     407 ..     266     411 .. 0.82

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 2.9e-07
                   SHHHHHHHHHCT-SEEEESHH...HHH-THHHHHHHHHHCGGGEEEEEEEEECEEEEETTTTEEEEEEHHHHHHHHHHTT-S...EEEEEETTTTTT CS
  His_biosynth  84 sledveelleagadkviigta...avknpelikelaekfgsqkivvaiDarrgykvaikgwreetgldavelakkleelgag...eilltdidrdGt 174
                   + e+++ l++ag d vi+ ++    + + ++ik + + +++      iD+ +g +v++++   +    ++    +  + g+g   + + +++ ++G 
    EEA20903.1 273 DKERLQMLVDAGLDIVILDSSqgnSMYQLDMIKYIKKTYPQ------IDVIAG-NVVTREQAAN----LIAAGADGLRIGMGsgsACITQEVMAVGR 358
                   6788999************9944445667777777777777......**9999.7777776666....5555555555555422278********** PP

                   SS---HHHHHHHHHHHSSEEEEESS--SHHHHHHHHHTTCSEEEESHHH CS
  His_biosynth 175 lsGpdleltkelaeavkipviasGGvgsledlkelksegvdavivgsal 223
                    +   +  + ++a+++ +p ia GG++++ ++ +  ++g++ +++g +l
    EEA20903.1 359 PQALSVRSVASFAARFGVPCIADGGIQNVGHIVKGLAMGASTIMMGGLL 407
                   ****************************************999999776 PP

>> Aldolase  KDPG and KHG aldolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.1     6e-06     0.011       9      82 ..     260     336 ..     253     353 .. 0.83
   2 ?   -0.5   0.0      0.38   6.8e+02     107     125 ..     383     401 ..     362     423 .. 0.64

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 6e-06
                 SEEEEE--SSGGGHHHHHHHHHHTT--EEEEET...TSTTHHHHHHHHHHH-TTSEEEEES--SHHHHHHHHHCT-S CS
    Aldolase   9 kvvpvivikdkedalplaeaLvagGlrvlevtl...rteaaldairvlrkerpdllvgaGtvlnaeqlaeakeaGaq 82 
                 ++++  +i   e  ++  + Lv+ Gl ++ +      +   ld+i+ ++k  p++ v aG v+++eq+a+  +aGa+
  EEA20903.1 260 QLIAAAAIGTRESDKERLQMLVDAGLDIVILDSsqgNSMYQLDMIKYIKKTYPQIDVIAGNVVTREQAANLIAAGAD 336
                 566677777777778888899999999876654111456679*********************************98 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.38
                 EESSHHHHHHHHHTT--EE CS
    Aldolase 107 GvstpseimlaldlGlkrl 125
                 G++++ +i  +l++G +++
  EEA20903.1 383 GIQNVGHIVKGLAMGASTI 401
                 5555555555555555443 PP

>> YpsA  YspA SLOG family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   0.0   1.1e-05      0.02      29      71 ..     274     316 ..     270     319 .. 0.93

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.1e-05
                 HHHHHHHHTTT--EEEE---TTHHHHHHHHHHTTTTT-TT-EE CS
        YpsA  29 kkklkelleeglewviisgqlGvelwaaevvleLkeeypelkl 71 
                 k++l+ l++ gl+ vi+  ++G  ++ +++++ +k++yp++ +
  EEA20903.1 274 KERLQMLVDAGLDIVILDSSQGNSMYQLDMIKYIKKTYPQIDV 316
                 6899***********************************9875 PP

>> PK  Pyruvate kinase, barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   3.4e-05      0.06       8      56 ..     265     313 ..     258     367 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 3.4e-05
                 EEESCCCTSHHHHHHHHHHTEEEEEEETTSS-HHHHHHHHHHHHHHHHT CS
          PK   8 ctlGPasesvekleklieaGlnvvrlnfshGsheehqerienvreaekk 56 
                 + +G   ++ e+l+ l++aGl++v l+ s G+  ++ + i+ ++++  +
  EEA20903.1 265 AAIGTRESDKERLQMLVDAGLDIVILDSSQGNSMYQLDMIKYIKKTYPQ 313
                 6799999****************************99999988876554 PP

>> ThiG  Thiazole biosynthesis protein ThiG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0      0.75   1.3e+03      97     184 ..     195     285 ..     193     291 .. 0.70
   2 ?   10.8   0.5   0.00012      0.22     166     210 ..     366     410 ..     343     415 .. 0.82

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.75
                 --BCETTTTEB-HHHHHHHHHHHHHTT-EEEEEE-S-HHHHHHHH..HTT-SEBEEBSSSTTS----S-HHHHHHHHHH-.SS-BEEES-- CS
        ThiG  97 EviadektLlPdvvetlkaaeiLvkeGFevlpYvsdDlvlarrle..evGcaavmPlaapiGsglGllnkealkiiieea.kvPvivDAGi 184
                 Ev++ + +  P  + + +a e+L +     lp v +D  l   l   ++  +   Pla+ +  ++ l +++a+ +  ++  ++ ++vDAG+
  EEA20903.1 195 EVMSTDLVTAPAGTTLAEANEVLRNSKKGKLPIVDKDGNLVSLLSrsDLRKNLHYPLASKLPHSKQLIAAAAIGTRESDKeRLQMLVDAGL 285
                 6667777777777778888888887777778888888777777752244445566888888888888888888776655548888888887 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00012
                 HHHHHHHH-SS-BEEES---SHHHHHHHHHTT-SEEEESHHHHTS CS
        ThiG 166 alkiiieeakvPvivDAGigspsdaaqamelGadavllntavaea 210
                  +  + +++ vP i D Gi +  ++++ + +Ga+++++   +a +
  EEA20903.1 366 SVASFAARFGVPCIADGGIQNVGHIVKGLAMGASTIMMGGLLAGT 410
                 466778899****************************98777655 PP

>> SHNi-TPR  SHNi-TPR
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   0.00024      0.43      21      37 ..      16      32 ..       9      33 .. 0.89
   2 ?   -3.2   0.0       3.3     6e+03      21      29 ..     506     514 ..     505     516 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00024
    SHNi-TPR 21 veDlrkaLeLreqllpp 37
                ++D++kaLe+ e+ +p+
  EEA20903.1 16 IQDYTKALEILEKQYPT 32
                79***********9985 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 3.3
    SHNi-TPR  21 veDlrkaLe 29 
                 v+Dl ++++
  EEA20903.1 506 VKDLHESVN 514
                 89****997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (545 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       371  (0.0206927); expected 358.6 (0.02)
Passed bias filter:                      330  (0.0184059); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.49
# Mc/sec: 3358.15
//
Query:       EEA20904.1  [L=226]
Description: oxidoreductase, short-chain dehydrogenase/reductase family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      5e-31  107.7   0.7    8.4e-29  100.4   0.7    2.1  1  adh_short      short chain dehydrogenase
    1.3e-28  100.2   1.4      1e-26   93.9   1.4    2.1  1  adh_short_C2   Enoyl-(Acyl carrier protein) reductase
     0.0049   16.8   0.0     0.0071   16.3   0.0    1.4  1  KR             KR domain
  ------ inclusion threshold ------
       0.03   14.4   0.1      0.052   13.6   0.1    1.3  1  FKBP_N_2       BDBT FKBP like N-terminal
      0.065   12.6   0.0       0.12   11.7   0.0    1.4  1  THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase,


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.4   0.7   2.3e-32   8.4e-29       1     178 [.      56     226 .]      56     226 .] 0.93

  Alignments for each domain:
  == domain 1  score: 100.4 bits;  conditional E-value: 2.3e-32
                 SEEEEES.....TTSHHHHHHHHHHHHTT-EEEE..EESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---S.S--S CS
   adh_short   1 kvvlvtG.....assGIGraiakelakeGakvvv..vdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGi.tgsg 91 
                 k vl+tG      ssGIGra+a  +a+eGa+v++  + +++e++e ++k +++e+++ + +++D+t++e+++++v++    +g+l++LvnNA+     +
  EEA20904.1  56 KNVLITGendnlSSSGIGRAVAVLMAREGADVTIahLPEEQEDAEDTKKMVEAENRSCFLFAGDLTNYENCRQVVDEHFRSYGSLNILVNNASQqFMCK 154
                 678888844444589*****************99777889999***************************************************65678 PP

                 SGGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEE CS
   adh_short  92 pfselseeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnava 178
                 +f +++ +++e v+  N+  +f +t+ +l++m+               + ++++++ Y+A+Kaa++g+trsla +l p+girvnava
  EEA20904.1 155 TFTDIDLNNVEHVFRSNVLQMFAMTKYALTYMK---------------ETRSPSMVDYAATKAAIVGFTRSLATQLIPKGIRVNAVA 226
                 99******************************9...............56789999*****************************96 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.9   1.4   2.9e-30     1e-26       4     170 ..      70     226 .]      67     226 .] 0.93

  Alignments for each domain:
  == domain 1  score: 93.9 bits;  conditional E-value: 2.9e-30
                   TSHHHHHHHHHHHTT-EEEEEESSGGH..HHHHHHHHHHTTSE.E.EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHH CS
  adh_short_C2   4 sgIGraiAkalaeeGaevvltdlneea..kkrveelaeelgae.v.lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreefd 96 
                   sgIGra+A ++a+eGa+v ++ l ee+  ++++++++e+ +++ + ++ D t+ e+++++v+e  +++g+l+ilvnna       + f++++ ++++
    EEA20904.1  70 SGIGRAVAVLMAREGADVTIAHLPEEQedAEDTKKMVEAENRScFlFAGDLTNYENCRQVVDEHFRSYGSLNILVNNASQQFM-CKTFTDIDLNNVE 165
                   8************************998778899999888877547********************************99998.9************ PP

                   HHHHHHTHHHHHHHHHHHHHCTSCCEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEE CS
  adh_short_C2  97 raldvnlyslfllakaalplmkeggsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavs 170
                   +++  n+  +f+++k+al +mke+ s             p+   y+a+Kaa++++tr+lA +l pkgiRvNav+
    EEA20904.1 166 HVFRSNVLQMFAMTKYALTYMKETRS-------------PSMVDYAATKAAIVGFTRSLATQLIPKGIRVNAVA 226
                   ******************99998754.............6666899**************************96 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0     2e-06    0.0071      10     113 ..      70     172 ..      58     214 .. 0.85

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 2e-06
                 SHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE--.-------TTT--HHHHHH CS
          KR  10 GgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaA.gvlrdklleemtaedleq 107
                  g+G+++a  +a++ga   +    +  ++ed++++ + +ea + ++ ++a D+++ ++ +++++e  ++ ++++  ++ A   ++ k++++ + +++e+
  EEA20904.1  70 SGIGRAVAVLMAREGADVTIAHLPE--EQEDAEDTKKMVEAENRSCFLFAGDLTNYENCRQVVDEHFRSYGSLNILVNNAsQQFMCKTFTDIDLNNVEH 166
                 589************8866665555..56666666777788889999**************************99887662568899999999999999 PP

                 HHTTTT CS
          KR 108 vlapKv 113
                 v+++ v
  EEA20904.1 167 VFRSNV 172
                 998876 PP

>> FKBP_N_2  BDBT FKBP like N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   1.5e-05     0.052      46     101 ..      47     102 ..      34     108 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 1.5e-05
    FKBP_N_2  46 llekleleeekeiviGealteideyierlleqmklgEtaevtikikaeesetesii 101
                 +  +++l++++++  Ge ++  +  i r++  +++ E a vti+  +ee+e+ +++
  EEA20904.1  47 YVGNNKLKDKNVLITGENDNLSSSGIGRAVAVLMAREGADVTIAHLPEEQEDAEDT 102
                 45566799***************************************999876554 PP

>> THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   3.3e-05      0.12      32      69 ..      51      93 ..      34     108 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 3.3e-05
                   ---TT-EEEEE--.....-TTTHHHHHHHHHCTT-EEEEE-TT CS
  THF_DHG_CYH_C 32 ielegkkvvvvGr.....snivgkplallLleknatVtvchsk 69
                    +l++k+v++ G+     s+ +g+++a+l+++++a Vt++h  
     EEA20904.1 51 NKLKDKNVLITGEndnlsSSGIGRAVAVLMAREGADVTIAHLP 93
                   5689999999997333335679******************965 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (226 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       599  (0.0334096); expected 358.6 (0.02)
Passed bias filter:                      425  (0.0237046); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 1535.54
//
Query:       EEA20905.1  [L=133]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-21   76.1   0.0    2.1e-21   75.7   0.0    1.1  1  DUF952    Protein of unknown function (DUF952)


Domain annotation for each model (and alignments):
>> DUF952  Protein of unknown function (DUF952)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.7   0.0   1.2e-25   2.1e-21      18      90 .]      29     112 ..      21     112 .. 0.90

  Alignments for each domain:
  == domain 1  score: 75.7 bits;  conditional E-value: 1.2e-25
                 -.-HHHHHHTSEE-EEHHHHHHHHHHHSTT--SEEEEEEESGGGTTTEEEEEG........GGGSEEEEESS..-EEGGGEEE. CS
      DUF952  18 g.ssldakdGFIHlStaeqvpetaarffagqedlvllkidasklaaavkweas........eggelfPHlYg..plplkaVvsv 90 
                 + s+ld ++GFIHlS+a qvp+t++ ff++++ +++l+++++k++++++we++        eg+ +fPHlY+  +l+ ++++sv
  EEA20905.1  29 PvSDLDLQSGFIHLSSARQVPNTLKFFFKDEPVVYVLRLEYAKVEENIRWESPdakicgprEGEGMFPHLYNglKLGKEEIESV 112
                 5599**************************666******************99*******65559*******888888888875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (133 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       190  (0.0105974); expected 358.6 (0.02)
Passed bias filter:                      183  (0.0102069); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.24s 00:00:00.67 Elapsed: 00:00:00.42
# Mc/sec: 950.51
//
Query:       EEA20906.1  [L=1667]
Description: Ras GTPase activating protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.1e-47  160.2   4.8    3.1e-47  160.2   4.8    2.6  2  RasGAP_C     RasGAP C-terminus
    6.2e-45  153.5   0.2    1.9e-44  151.9   0.0    2.0  2  RasGAP       GTPase-activator protein for Ras-like GTPase
    4.2e-12   46.2   0.0    1.3e-11   44.6   0.0    1.9  1  CH           Calponin homology (CH) domain
    1.1e-08   34.1  52.6       0.51   10.3   0.5   13.6 16  IQ           IQ calmodulin-binding motif
     0.0068   16.2   0.1      0.025   14.4   0.0    2.0  2  CAMSAP_CH    CAMSAP CH domain
  ------ inclusion threshold ------
      0.021   14.8   0.3       0.04   13.9   0.3    1.4  1  Trypan_PARP  Procyclic acidic repetitive protein (PARP)


Domain annotation for each model (and alignments):
>> RasGAP_C  RasGAP C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.4       1.2   3.7e+03      58     105 ..     565     611 ..     559     635 .. 0.65
   2 !  160.2   4.8     1e-50   3.1e-47       1     137 []    1448    1588 ..    1448    1588 .. 0.98

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.2
    RasGAP_C  58 tlktLseknnylesqlesYkayienvleqlkkkkgklpfskqyfkkre 105
                  +++L+ k +  es ++s +a i+ +l+  +++  +++++k + k+++
  EEA20906.1 565 QISQLKTKMRREESGVKSIQAAIRGALQRKHASD-RIQQTKGAEKEVK 611
                 5667777777778888888888888887765552.3444444444444 PP

  == domain 2  score: 160.2 bits;  conditional E-value: 1e-50
    RasGAP_C    1 lvelkkkalenlkeLeelgvisrennyqellneIakdirnkgrlrekrkeElesleetlktLseknnylesqlesYkayienvleqlkkkkgk.... 93  
                  +++lk+ alen+++Le+ g+isr+n+yq++ln+Ia dir+k+r+r +r++Eles++ tl++L+ + ++le+ql++Y++yie+++ +l++kkgk    
  EEA20906.1 1448 YADLKSVALENILQLEQFGKISRHNQYQDILNAIAVDIRTKHRRRIQRERELESVRLTLSRLNGQAEFLEQQLKTYNDYIEHSMTTLQNKKGKkrfl 1544
                  899****************************************************************************************777*** PP

    RasGAP_C   94 lpfskqyfkkrelkksgklpkfgsykysakqLeekgVLleiegl 137 
                  lpf+kq+ ++rel+k+g++ k+gsykysa+ L+ekgVL++++g+
  EEA20906.1 1545 LPFTKQWDHERELQKTGRVFKLGSYKYSARTLAEKGVLVHWKGY 1588
                  ****************************************9985 PP

>> RasGAP  GTPase-activator protein for Ras-like GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   0.0       3.8   1.1e+04      62      83 ..     989    1010 ..     985    1018 .. 0.61
   2 !  151.9   0.0   6.4e-48   1.9e-44       1     208 []    1039    1247 ..    1039    1247 .. 0.99

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 3.8
      RasGAP   62 lelDPrkiyeelkkkkesktgk 83  
                  l++ P+++++ ++k +e+ t++
  EEA20906.1  989 LQTQPQYLARLFRKLREQNTSD 1010
                  5666777777777777765443 PP

  == domain 2  score: 151.9 bits;  conditional E-value: 6.4e-48
      RasGAP    1 liseliklElessenpndllrsnsvvsklleeytkrpegqeyLkkilkpllqkil.ekedlnlelDPrkiyeelkkkkesktgkksessgkksekea 96  
                  li++ ik+E+  + +++d +r ns++ kl+  y+k+p+ +++L++il+p++++ + e++d +le+DP++iy+ ++ ++e +tg+ks+++ ++ ++ a
  EEA20906.1 1039 LITRSIKEEILGCPSLQDWVRCNSFWLKLFVAYVKSPRDRKFLREILNPIVKEWIlENPDIDLESDPMQIYRTAIINEELRTGQKSRRPLDIPKEAA 1135
                  68899************************************************988***************************************** PP

      RasGAP   97 selekvsqmleknldkLkelvneildsIfksleqlPvgiRiickqirekvkekfpdaseeeilnligsflflrfliPaivnPklfglvdkqiseeqr 193 
                  +++++++ +++++l++L+++ +++l +  + l ++P+giR+i+k ++e + +++ ++++  +l++ g+ ++ ++l  a+++P+  g+vd+ ++++++
  EEA20906.1 1136 IRDPETRAIFIQHLENLRDISEQFLGRFHEALPKMPFGIRYIAKELYEMLLAQYNNEDPGLVLQVAGQCIWKNYLQSAVLEPEKHGVVDHSLDPKHK 1232
                  ************************************************************************************************* PP

      RasGAP  194 rnLtliaKllqnlan 208 
                  + L++iaK+l ++a+
  EEA20906.1 1233 KDLSEIAKVLSQVAS 1247
                  ************985 PP

>> CH  Calponin homology (CH) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.6   0.0   4.4e-15   1.3e-11       6     105 ..     284     383 ..     280     387 .. 0.92

  Alignments for each domain:
  == domain 1  score: 44.6 bits;  conditional E-value: 4.4e-15
                 HHHHHHHHHHTTSTTSSTTSCHHHHHTTSHHHHHHHHHHSTTTSSGGGSTTT.HHHHHHHHHHHHHHHHHHTTCHTTSS.-HHHHHTTSHH.HHHHHHH CS
          CH   6 ellrWinshleeagpkvkvedfeedlrDGvlLckLlnklapglvdkkklnks.efkkleNinlaldvaekklgvpkvli.eaedlvegknk.svltlla 101
                 e+ +Wi++++++++p +   ++ee+lrDGv L++++++l+p+       n++ ++++ +Ni+l++ +++ ++ +p++   e  dl+e+kn  +v+++++
  EEA20906.1 284 EAKEWIEDVIQKEIPPI--VQLEEALRDGVTLAEIVQALYPNRMLRIFRNPRlQYRHSDNIALFFRFLD-EVALPDIFRfELIDLYEKKNIpKVIHCIH 379
                 5789******9976665..7***********************888888888*****************.***************************** PP

                 HHHH CS
          CH 102 qLfr 105
                 +L++
  EEA20906.1 380 ALSW 383
                 *987 PP

>> IQ  IQ calmodulin-binding motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.1      0.43   1.3e+03       7      19 ..     467     479 ..     467     480 .. 0.87
   2 ?   -1.1   0.5      0.79   2.4e+03       7      17 ..     497     507 ..     497     509 .. 0.83
   3 !    9.8   0.2   0.00024      0.72       2      18 ..     518     534 ..     517     535 .. 0.88
   4 !    7.8   0.3     0.001       3.1       4      18 ..     550     564 ..     549     566 .. 0.89
   5 !    9.1   0.2   0.00041       1.2       7      19 ..     583     595 ..     578     596 .. 0.90
   6 !    7.1   0.0    0.0018       5.4       7      19 ..     613     625 ..     607     626 .. 0.86
   7 ?   -0.5   0.0       0.5   1.5e+03       4      17 ..     640     653 ..     638     656 .. 0.77
   8 ?    2.1   0.1     0.074   2.2e+02       6      21 .]     672     687 ..     671     687 .. 0.91
   9 ?   -2.8   0.0       2.8   8.4e+03       7      18 ..     703     714 ..     703     715 .. 0.81
  10 !    6.0   0.0     0.004        12       4      19 ..     730     745 ..     728     746 .. 0.93
  11 ?    2.5   0.0     0.054   1.6e+02       5      19 ..     761     775 ..     759     776 .. 0.91
  12 ?    0.5   0.0      0.25   7.4e+02       4      17 ..     790     803 ..     787     806 .. 0.86
  13 !   10.3   0.5   0.00017      0.51       7      20 ..     823     836 ..     823     837 .. 0.94
  14 !    6.7   0.1    0.0024       7.1       3      21 .]     849     867 ..     847     867 .. 0.86
  15 ?   -2.9   0.1       2.9   8.8e+03       8      16 ..    1203    1211 ..    1203    1211 .. 0.91
  16 ?   -2.9   0.1         3   9.1e+03      10      18 ..    1584    1592 ..    1584    1593 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.43
                 HHHHHHHHHHHHH CS
          IQ   7 IQaawRGylaRkr 19 
                 +Q ++RG l R +
  EEA20906.1 467 LQTQIRGALLRVK 479
                 7*******99965 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.79
                 HHHHHHHHHHH CS
          IQ   7 IQaawRGylaR 17 
                 +Q+++RG +aR
  EEA20906.1 497 LQSRIRGDWAR 507
                 7******7777 PP

  == domain 3  score: 9.8 bits;  conditional E-value: 0.00024
                 HHHHHHHHHHHHHHHHH CS
          IQ   2 kaaikIQaawRGylaRk 18 
                 + a+ +Qa+ RG+l+R 
  EEA20906.1 518 QFAVNLQAVSRGFLVRA 534
                 679*************5 PP

  == domain 4  score: 7.8 bits;  conditional E-value: 0.001
                 HHHHHHHHHHHHHHH CS
          IQ   4 aikIQaawRGylaRk 18 
                 ++kIQ+ +RG +aR 
  EEA20906.1 550 VLKIQKLVRGRKARA 564
                 579***********6 PP

  == domain 5  score: 9.1 bits;  conditional E-value: 0.00041
                 HHHHHHHHHHHHH CS
          IQ   7 IQaawRGylaRkr 19 
                 IQaa+RG l+Rk+
  EEA20906.1 583 IQAAIRGALQRKH 595
                 9***********8 PP

  == domain 6  score: 7.1 bits;  conditional E-value: 0.0018
                 HHHHHHHHHHHHH CS
          IQ   7 IQaawRGylaRkr 19 
                 +Q a+RG++aR+ 
  EEA20906.1 613 LQTAIRGMQARRS 625
                 8**********95 PP

  == domain 7  score: -0.5 bits;  conditional E-value: 0.5
                 HHHHHHHHHHHHHH CS
          IQ   4 aikIQaawRGylaR 17 
                 ++ +Q+++R+  +R
  EEA20906.1 640 VLFLQSVIRASAQR 653
                 6789*****86666 PP

  == domain 8  score: 2.1 bits;  conditional E-value: 0.074
                 HHHHHHHHHHHHHHHH CS
          IQ   6 kIQaawRGylaRkryk 21 
                 ++Q+ +R+  +Rk++k
  EEA20906.1 672 TLQSSIRAAAVRKHLK 687
                 79***********986 PP

  == domain 9  score: -2.8 bits;  conditional E-value: 2.8
                 HHHHHHHHHHHH CS
          IQ   7 IQaawRGylaRk 18 
                 +Q+ +R+   R 
  EEA20906.1 703 LQSIVRANALRS 714
                 7*****987775 PP

  == domain 10  score: 6.0 bits;  conditional E-value: 0.004
                 HHHHHHHHHHHHHHHH CS
          IQ   4 aikIQaawRGylaRkr 19 
                 a+++Q+  RG+  Rkr
  EEA20906.1 730 ALRLQSMTRGMFLRKR 745
                 789************8 PP

  == domain 11  score: 2.5 bits;  conditional E-value: 0.054
                 HHHHHHHHHHHHHHH CS
          IQ   5 ikIQaawRGylaRkr 19 
                 +++Q+  R+ l+R+ 
  EEA20906.1 761 TTLQSLTRAALVRRD 775
                 89***********95 PP

  == domain 12  score: 0.5 bits;  conditional E-value: 0.25
                 HHHHHHHHHHHHHH CS
          IQ   4 aikIQaawRGylaR 17 
                 ++ +Q  +R++l+R
  EEA20906.1 790 VVQLQGLIRAMLVR 803
                 678999*******9 PP

  == domain 13  score: 10.3 bits;  conditional E-value: 0.00017
                 HHHHHHHHHHHHHH CS
          IQ   7 IQaawRGylaRkry 20 
                 +Qa++RGyl R r+
  EEA20906.1 823 LQAHIRGYLIRLRF 836
                 7**********998 PP

  == domain 14  score: 6.7 bits;  conditional E-value: 0.0024
                 HHHHHHHHHHHHHHHHHHH CS
          IQ   3 aaikIQaawRGylaRkryk 21 
                  +ik Q+++RG  + ++yk
  EEA20906.1 849 KVIKVQSFVRGKIQGQAYK 867
                 68*********99988886 PP

  == domain 15  score: -2.9 bits;  conditional E-value: 2.9
                  HHHHHHHHH CS
          IQ    8 QaawRGyla 16  
                  Q+ w+ yl+
  EEA20906.1 1203 QCIWKNYLQ 1211
                  9******96 PP

  == domain 16  score: -2.9 bits;  conditional E-value: 3
                  HHHHHHHHH CS
          IQ   10 awRGylaRk 18  
                  +w+Gy  R+
  EEA20906.1 1584 HWKGYTERQ 1592
                  8****9987 PP

>> CAMSAP_CH  CAMSAP CH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.0   8.3e-06     0.025       8      81 ..     295     365 ..     290     368 .. 0.81
   2 ?   -3.4   0.1       3.1   9.2e+03      55      70 ..    1635    1650 ..    1631    1654 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 8.3e-06
   CAMSAP_CH   8 plippvedllrdlsdGvaLaalihfYcPqliklediclkesmsladslyNiqllqefcerkLgnsvfhltleDl 81 
                 + ipp+  l + l+dGv La++++ ++P+ + l  i +++   +    +Ni l++ f  +    ++f ++l Dl
  EEA20906.1 295 KEIPPIVQLEEALRDGVTLAEIVQALYPNRM-L-RI-FRNPRLQYRHSDNIALFFRFLDEVALPDIFRFELIDL 365
                 6789999999*******************99.4.34.445555555669*****99998876688888888887 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 3.1
   CAMSAP_CH   55 lyNiqllqefcerkLg 70  
                  +yN+ ++ +f+e +L 
  EEA20906.1 1635 QYNNTQFLDFFEGTLR 1650
                  79*********98884 PP

>> Trypan_PARP  Procyclic acidic repetitive protein (PARP)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.3   1.4e-05      0.04      54      87 ..     426     459 ..     381     470 .. 0.54

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.4e-05
  Trypan_PARP  54 tngtdpepepepepepepepepepepetepeeep 87 
                   +g  +    epepepepep    e+  e e + 
   EEA20906.1 426 FSGMGATFGAEPEPEPEPEPVETEEERIERELHE 459
                  4444444444455555555533333322222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1667 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1194  (0.066596); expected 358.6 (0.02)
Passed bias filter:                      527  (0.0293937); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.04u 0.27s 00:00:01.31 Elapsed: 00:00:00.46
# Mc/sec: 10965.05
//
Query:       EEA20907.1  [L=538]
Description: Golgi to endosome transport protein (Ent3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.7e-46  155.0   0.2    1.2e-45  154.6   0.2    1.2  1  ENTH      ENTH domain
    3.2e-05   23.1   0.1    4.6e-05   22.5   0.1    1.2  1  ANTH      ANTH domain
  ------ inclusion threshold ------
        1.2    9.1   6.1        2.7    7.9   0.1    2.5  2  DUF5102   Domain of unknown function (DUF5102)


Domain annotation for each model (and alignments):
>> ENTH  ENTH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  154.6   0.2     2e-49   1.2e-45       1     123 [.      32     154 ..      32     156 .. 0.98

  Alignments for each domain:
  == domain 1  score: 154.6 bits;  conditional E-value: 2e-49
                 --HHHHHHHHHTSSSSSS--HHHHHHHHHHTTSHHHHHHHHHHHHHHHHH--GGGHHHHHHHHHHHHHHHHHS-HHHHHHHHHTHHHHHGGGG---B-T CS
        ENTH   1 yseteskvreatnndpwGpsnkllteiarltyskkelseiisvitkrLqnnkgkewrsvlKaLtlieYLlknGseqvidwlkenisiiktlsefkyide 99 
                 y+e+e+kvreatnn+pwG+s++l++eia+ t++++ l+ei+ +i+kr+++++ +ewr+++KaL+l+e+L+k+Gse+v+d++++++s+i++l++f+yid 
  EEA20907.1  32 YTEMEAKVREATNNEPWGASSTLMQEIASGTHNYHLLNEIMPMIYKRFTEKTAEEWRQIYKALQLLEFLIKHGSERVVDDARSHLSLIRMLRQFHYIDA 130
                 799************************************************************************************************ PP

                 TS-B-HHHHHHHHHHHHHHHT-HH CS
        ENTH 100 egkdeglniRkkakkiislledee 123
                 +gkd+g+n+R++++++++ll d +
  EEA20907.1 131 NGKDQGINVRNRSQELVKLLGDVD 154
                 ********************9976 PP

>> ANTH  ANTH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5   0.1   7.7e-09   4.6e-05       2     108 ..      35     140 ..      34     148 .. 0.86

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 7.7e-09
                 HHHHHHHHT-SSS---HHHHHHHHHHHCSTTS-HHHHHHHHHHHCTSS...SHHHHHHHHHHHHHHHHHS-CHHHHHHHHTT-----TT---TSHHHST CS
        ANTH   2 levavvKAtshdevPpkekhvreilvltssrekvaalvwalsrrlklt..rnwvvalKaLilvHklLreGhpsveqellsarrrisellnlssfddsss 98 
                 +e+ v+ At+ +   +   +++ei ++t++ + +++++ ++ +r +++  ++w + +KaL l+  l+++G+++v  ++ s+ + i+ l +++  d    
  EEA20907.1  35 MEAKVREATNNEPWGASSTLMQEIASGTHNYHLLNEIMPMIYKRFTEKtaEEWRQIYKALQLLEFLIKHGSERVVDDARSHLSLIRMLRQFHYID---A 130
                 5778999*************************************97652268*************************999999998888888733...3 PP

                 HHHHHHHHHH CS
        ANTH  99 kswdysafir 108
                 +++d++ ++r
  EEA20907.1 131 NGKDQGINVR 140
                 5666665555 PP

>> DUF5102  Domain of unknown function (DUF5102)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   2.5     0.031   1.8e+02       7      62 ..     221     279 ..     216     291 .. 0.56
   2 ?    7.9   0.1   0.00046       2.7      14      45 ..     310     342 ..     302     375 .. 0.47

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.031
     DUF5102   7 dFeegaeaeddddFgDFddgfqeee....aees.eeaeeeepa.epsasslsfplldfesld 62 
                 dF + a+  +   F+++d++ +e++    + ++ +e++++++a +++++++++ l df + d
  EEA20907.1 221 DFRDTAR--RSSRFEEYDEEDDEPStapaS-RRpAESKAQAKApQQPPKAQEVDLFDFGDDD 279
                 7777763..345688888655555555541.3322233332232555555666778886655 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.00046
     DUF5102  14 aeddddFgDFddgfqeee.....aeeseeaeeeepae 45 
                  +ddddF+DF+   + ++     +   ++a+++ +a+
  EEA20907.1 310 GDDDDDFDDFQSA-SPPAaptavT---TTASTQFVAP 342
                 378999****953.2222222321...2222222221 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (538 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       910  (0.0507558); expected 358.6 (0.02)
Passed bias filter:                      552  (0.0307881); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.67u 0.30s 00:00:00.97 Elapsed: 00:00:00.49
# Mc/sec: 3317.75
//
Query:       EEA20908.1  [L=915]
Description: cell polarity protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.8e-25   85.9   5.8      2e-13   49.7   0.6    2.7  2  GIT_SHD         Spa2 homology domain (SHD) of GIT
    4.9e-05   23.4   0.1    4.9e-05   23.4   0.1    3.7  5  GIT1_C          G protein-coupled receptor kinase-interacting
     0.0027   18.2  16.7     0.0027   18.2  16.7    3.1  3  APG6_N          Apg6 coiled-coil region
  ------ inclusion threshold ------
      0.033   13.4  37.3       0.21   10.7  14.2    2.4  2  Taxilin         Myosin-like coiled-coil protein
       0.05   12.9  23.9      0.042   13.2  20.4    2.3  2  DUF4407         Domain of unknown function (DUF4407)
      0.077   13.0  36.8       0.66   10.0   5.2    3.9  3  CENP-F_leu_zip  Leucine-rich repeats of kinetochore protein C
        0.2   11.5  40.6      0.016   15.0  25.6    3.0  3  ERM             Ezrin/radixin/moesin family
       0.29    9.9  27.7         28    3.4  27.7    2.2  1  Fmp27_WPPW      RNA pol II promoter Fmp27 protein domain
          1    7.4  30.8       0.18    9.9  20.6    2.2  2  EzrA            Septation ring formation regulator, EzrA
        1.5    9.0  30.3       0.84    9.8   2.7    4.9  4  bZIP_1          bZIP transcription factor
        2.6    8.2  10.8      0.062   13.5   1.2    2.6  2  XLF             XLF-Cernunnos, XRcc4-like factor, NHEJ compon
        4.6    7.4  40.1        2.5    8.3   9.2    3.5  2  ATG16           Autophagy protein 16 (ATG16)
        4.6    7.6  12.4       0.14   12.5   0.3    4.0  3  DUF948          Bacterial protein of unknown function (DUF948
        5.4    7.2  44.7        0.9    9.8  21.5    4.2  4  Jnk-SapK_ap_N   JNK_SAPK-associated protein-1
        6.8    7.1  35.3        6.2    7.2  12.1    2.7  2  Fez1            Fez1
        9.9    6.8  10.5         11    6.6   0.8    4.1  2  HisKA_3         Histidine kinase


Domain annotation for each model (and alignments):
>> GIT_SHD  Spa2 homology domain (SHD) of GIT
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.7   0.6   1.8e-16     2e-13       1      29 []     134     162 ..     134     162 .. 0.98
   2 !   38.0   0.5   7.9e-13   8.9e-10       1      27 [.     192     218 ..     192     218 .. 0.99

  Alignments for each domain:
  == domain 1  score: 49.7 bits;  conditional E-value: 1.8e-16
     GIT_SHD   1 ARqKLarLsnkqFeeLvtDVydEldRRet 29 
                 AR+KL+rLs++qF+eL+tDV+dEl RR++
  EEA20908.1 134 ARDKLLRLSPTQFHELSTDVFDELVRRQQ 162
                 9**************************96 PP

  == domain 2  score: 38.0 bits;  conditional E-value: 7.9e-13
     GIT_SHD   1 ARqKLarLsnkqFeeLvtDVydEldRR 27 
                 ARqKLa+L   +F +L+tDV++El+RR
  EEA20908.1 192 ARQKLASLQHPRFRDLATDVFCELERR 218
                 9*************************9 PP

>> GIT1_C  G protein-coupled receptor kinase-interacting protein 1 C term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   1.1      0.56   6.3e+02      58      95 ..     416     453 ..     392     461 .. 0.79
   2 ?   -0.2   0.2      0.95   1.1e+03      61     101 ..     467     507 ..     460     512 .. 0.78
   3 ?   -1.2   0.3       1.8   2.1e+03       4      47 ..     491     536 ..     481     558 .. 0.50
   4 ?   -3.2   0.0       7.8   8.8e+03      19      50 ..     593     624 ..     586     653 .. 0.75
   5 !   23.4   0.1   4.4e-08   4.9e-05      11     115 ..     787     898 ..     783     900 .. 0.89

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.56
      GIT1_C  58 eetlrtaLkqLtssaerLqeeCeelqeaeseskedikk 95 
                 +++l+++L++++++++ Lq++  ++qe+++ ++++++k
  EEA20908.1 416 KSELENKLTDVENANTYLQNKIDQMQEEHAMKEQELRK 453
                 5688899******************9944444444333 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.95
      GIT1_C  61 lrtaLkqLtssaerLqeeCeelqeaeseskedikketqqvi 101
                 l++  ++L++  + Lq+e +e q++++e+ +d+ ++ ++++
  EEA20908.1 467 LQQRYSELETRHKSLQSELQEQQKTTEEVRRDASNFLKEMR 507
                 55666788899999999999999988888888888777765 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 1.8
      GIT1_C   4 sseeVvrkteqitkriqeLlqaaqe..ekkesfvpcaerIqsaVqd 47 
                 ++eeV r      k+++++ + +++  e++e+  + ++r ++ V++
  EEA20908.1 491 TTEEVRRDASNFLKEMRAMSERSNAtwEQEEKLSRDVNRLEEEVKE 536
                 3444444444444444444444443223444444444444444444 PP

  == domain 4  score: -3.2 bits;  conditional E-value: 7.8
      GIT1_C  19 iqeLlqaaqeekkesfvpcaerIqsaVqdlva 50 
                 i eLl++a++++ + +    + +  aV+ l++
  EEA20908.1 593 IDELLRSARSGEPNLVLDQMKVVVVAVRHLMN 624
                 77888888877777777777777777776654 PP

  == domain 5  score: 23.4 bits;  conditional E-value: 4.4e-08
      GIT1_C  11 kteqitkriqeLlqaaqeekk.esfvpcaerIqsaVqdlvalfpenlseetlrta........LkqLtssaerLqeeCeelqeaeseskedikketqqv 100
                 +te +++ iq+L+++ + +++ +++ ++ + I  +V ++va   + +++ +++ a        +++L s + rL +  +e +e   es+e+++  t ++
  EEA20908.1 787 QTEGLVQTIQALVASIRGAEHiSAIRNHISAISIVVGNVVASTDHAMDKAEISPAvrerlgpvVQSLASCSDRLSNTAAEGEE--LESPEQLRDLTAKL 883
                 7999*************8665166778999**************999999998866777888899*********999888888..899*********** PP

      GIT1_C 101 iqcAydiAkaaKqLv 115
                    A++iA+ +K+Lv
  EEA20908.1 884 PPIAFEIARETKELV 898
                 **************9 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7  19.3     0.076        85      13     103 ..     366     456 ..     360     461 .. 0.87
   2 !   18.2  16.7   2.4e-06    0.0027      51     133 .]     466     548 ..     461     548 .. 0.97
   3 ?   -2.8   0.4       7.8   8.7e+03      61      91 ..     867     897 ..     851     908 .. 0.51

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.076
      APG6_N  13 eldkqleqaekerdaYeeflkklkkekkeeekqdeeleeleeeleklekeeeelleeLkelekereeleaelaaleeelealeeeeerfwr 103
                   + q++++++  d++++ +k+ ++e +  ++++e+ + +  e ++ e  ++el+++L ++e+++  l++++ + +ee++ +e+e ++ ++
  EEA20908.1 366 DSQAQVATLQERVDELQSLMKNKDEEISRLQDEQEKSQISTSERDEWEGVKSELENKLTDVENANTYLQNKIDQMQEEHAMKEQELRKQIE 456
                 5678899999999999999999999988777677777778888999***************************************988765 PP

  == domain 2  score: 18.2 bits;  conditional E-value: 2.4e-06
      APG6_N  51 eleeeleklekeeeelleeLkelekereeleaelaaleeelealeeeeerfwreynelqlelleleeeldsleaqyehaqnql 133
                 el++++++le   ++l++eL+e +k+ ee++++ ++  +e +a+ e  ++ w++  +l++++++leee +  +++y  a++ql
  EEA20908.1 466 ELQQRYSELETRHKSLQSELQEQQKTTEEVRRDASNFLKEMRAMSERSNATWEQEEKLSRDVNRLEEEVKEWKNRYIRAKTQL 548
                 7999**************************************************************************99997 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 7.8
      APG6_N  61 keeeelleeLkelekereeleaelaaleeel 91 
                  ee e  e+L++l ++   ++ e+a  ++el
  EEA20908.1 867 GEELESPEQLRDLTAKLPPIAFEIARETKEL 897
                 3344444445555444444444444444444 PP

>> Taxilin  Myosin-like coiled-coil protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0  15.1    0.0013       1.4      13     109 ..     364     456 ..     357     458 .. 0.90
   2 ?   10.7  14.2   0.00019      0.21      22     101 ..     466     549 ..     464     555 .. 0.87

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0013
     Taxilin  13 lespeekleaLvkkyaelleerkrlqkqlkklkkkleqlqkekeqlqaelskaalaksKLekLcRelqkqnkklkeeskqrareeeekrkelaekfq 109
                 l++++ ++++L++++ el + +k++++++  l    +  q++ + +++e++++  +ks Le+   ++ ++n  l+++  q+++e   k +el ++ +
  EEA20908.1 364 LADSQAQVATLQERVDELQSLMKNKDEEISRL----QDEQEKSQISTSERDEWEGVKSELENKLTDVENANTYLQNKIDQMQEEHAMKEQELRKQIE 456
                 577899*********************99994....455556667889*******************************************999876 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 0.00019
     Taxilin  22 aLvkkyaelleerkrlqkqlkklkkkleqlqkekeqlqaels....kaalaksKLekLcRelqkqnkklkeeskqrareeeekr 101
                 +L+++y+el + +k+lq++l++++k++e++ ++  +  +e++    +++++ +  ekL+R++ +  +++ke  ++ +r + + r
  EEA20908.1 466 ELQQRYSELETRHKSLQSELQEQQKTTEEVRRDASNFLKEMRamseRSNATWEQEEKLSRDVNRLEEEVKEWKNRYIRAKTQLR 549
                 79*******************************998777764222278899999*****************9999999888776 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2  20.4   3.7e-05     0.042     128     256 ..     364     515 ..     345     519 .. 0.71
   2 ?    0.5   0.2      0.28   3.1e+02     133     203 ..     518     597 ..     510     662 .. 0.61

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 3.7e-05
     DUF4407 128 aaaltaelaeleaqiaalqaeidaaearldalraeaqkeldgtk............gtgttgvaGkgpaakekkaqldaaqaelaelkakld....... 207
                  a+++a++a+l++++++lq+ ++++++++++l++e +k    t+             ++ t v+   ++    ++++d+ q+e a  +++l+       
  EEA20908.1 364 LADSQAQVATLQERVDELQSLMKNKDEEISRLQDEQEKSQISTSerdewegvkselENKLTDVENANTY---LQNKIDQMQEEHAMKEQELRkqieaah 459
                 445888999999999999999999999999999988877776555444444433333333333333333...333344444333333333336666999 PP

     DUF4407 208 .......atarlaalraelaeleaerakeraasqaaaaaddGllarlealdrltke 256
                         ++r ++l+++ ++l++e++++++++++ +++++ +l++++a+++ +++
  EEA20908.1 460 gagvhveLQQRYSELETRHKSLQSELQEQQKTTEEVRRDASNFLKEMRAMSERSNA 515
                 **************************************************987665 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.28
     DUF4407 133 aelaeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGk.gpaake..........kkaqldaaqaelaelk 203
                 ++ ++l +++++l++e+++ ++r+ +++++++   + t   g+++ + + g aa+e          k+++ ++ q  ++el 
  EEA20908.1 518 EQEEKLSRDVNRLEEEVKEWKNRYIRAKTQLRHLRTSTV--GIPNLHTDvGMAAREnelihehglvKDSHVTKFQMSIDELL 597
                 455667777777777777777777777777776666533..33333322033333344555555555555555555555555 PP

>> CENP-F_leu_zip  Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   3.4     0.024        27      88     127 ..     363     402 ..     349     409 .. 0.80
   2 ?   10.0   5.2   0.00059      0.66       1      46 [.     412     457 ..     412     467 .. 0.89
   3 ?    8.7  12.9    0.0014       1.6      15     104 ..     467     556 ..     456     577 .. 0.89

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.024
  CENP-F_leu_zip  88 elqkkqervseLeslnsslenlleekEqekvqmkeeskaa 127
                      l ++q +v +L+++  +l++l+++k +e  ++++e++++
      EEA20908.1 363 FLADSQAQVATLQERVDELQSLMKNKDEEISRLQDEQEKS 402
                     5677888888888888888888888888888888777664 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00059
  CENP-F_leu_zip   1 DekkklhvlekLKeserkadsLkdkvenLerelemseenqekvile 46 
                     +e  k ++++kL  +e  +  L++k+++++ e+ m e+++ k i  
      EEA20908.1 412 WEGVKSELENKLTDVENANTYLQNKIDQMQEEHAMKEQELRKQIEA 457
                     67778999******************************99887655 PP

  == domain 3  score: 8.7 bits;  conditional E-value: 0.0014
  CENP-F_leu_zip  15 serkadsLkdkvenLerelemseenqekvileaEtskaevetlkeeieelaeelreleldLvalrsekeeLekelqkkqervseLeslns 104
                      +++ + L+ + ++L++el+++++  e+v ++a +  +e+ ++ e  +   e+ ++l+ d++ l +e +e ++     + +   L ++ +
      EEA20908.1 467 LQQRYSELETRHKSLQSELQEQQKTTEEVRRDASNFLKEMRAMSERSNATWEQEEKLSRDVNRLEEEVKEWKNRYIRAKTQLRHLRTSTV 556
                     67788899***********************************************************99988887777777777777665 PP

>> ERM  Ezrin/radixin/moesin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0       1.1   1.2e+03     114     195 ..     102     200 ..      98     202 .. 0.71
   2 ?    1.3   5.9      0.23   2.5e+02      80     121 ..     367     408 ..     351     421 .. 0.83
   3 ?   15.0  25.6   1.4e-05     0.016       3     133 ..     426     555 ..     424     604 .. 0.66

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 1.1
         ERM 114 eareaeeeakekllealstpskseseenveeseteeeeenseeesaeletdeveklsleieee.................RvtylekskrlqeqLkeLk 195
                 +++e++ +  ++++++l +p+ s+ ++ ++++ +++    s ++ +el+td  ++l+++++                   R +  ek ++ +++L  L+
  EEA20908.1 102 RMEESLAQHYNAVRRFLGNPHASDRAAMKTNKARDKLLRLSPTQFHELSTDVFDELVRRQQAAggpgrpprtdippslppRPDFHEKRNQARQKLASLQ 200
                 566677777778888888886665545555555555555555566899999888888888877888888888888888888888888888888888876 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.23
         ERM  80 lerklreaeleaarleeeserkeeeaerLkeeleeareaeee 121
                  +++++  ++++ +l++ +++k+ee +rL++e e+ + +  e
  EEA20908.1 367 SQAQVATLQERVDELQSLMKNKDEEISRLQDEQEKSQISTSE 408
                 567888999999999999999999999999999998877655 PP

  == domain 3  score: 15.0 bits;  conditional E-value: 1.4e-05
         ERM   3 aerekreleerLkqlqeeaekaqeaLreseetae......lLaekarraeeeaelLeqkaaeaeeeiqrlkesaekeeeekeklerklreaeleaarle 95 
                 +e+ +  l++++ q+qee ++++++Lr++ e a+      +L+++  ++e+  + L+ + +e ++ +++++++a++  +e +++ ++ ++  ++ ++l 
  EEA20908.1 426 VENANTYLQNKIDQMQEEHAMKEQELRKQIEAAHgagvhvELQQRYSELETRHKSLQSELQEQQKTTEEVRRDASNFLKEMRAMSERSNATWEQEEKLS 524
                 6788899************************99733333355555555566666666666666666666666666666666666666666666666666 PP

         ERM  96 eeserkeeeaerLkeeleeareaeeeakekllealstp 133
                 ++++r eee++++k++ ++a+ +++       ++ +++
  EEA20908.1 525 RDVNRLEEEVKEWKNRYIRAKTQLR-------HLRTST 555
                 6666666666666666666655554.......444444 PP

>> Fmp27_WPPW  RNA pol II promoter Fmp27 protein domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4  27.7     0.025        28     169     290 ..     367     549 ..     361     553 .. 0.77

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.025
  Fmp27_WPPW 169 ervqkelleeRleeleeqiekleekleelelkseke......deelkeeieelekeikelkeklefletlledlkeseesse................. 244
                  + q   l+eR++el++ +++++e++++l++++ek+      ++e +   +ele+++ +++++ + l++ +++++e+++ +e                 
  EEA20908.1 367 SQAQVATLQERVDELQSLMKNKDEEISRLQDEQEKSqistseRDEWEGVKSELENKLTDVENANTYLQNKIDQMQEEHAMKEqelrkqieaahgagvhv 465
                 578999****************************98787666566666677788888888888888888888888887766699*************** PP

  Fmp27_WPPW 245 ..............................eeeskskelsaastsesfselde.............................lasseesaseFknRFii 284
                                               +                     +                             +++ ee ++e+knR+i 
  EEA20908.1 466 elqqryseletrhkslqselqeqqktteevR---------------------RdasnflkemramsersnatweqeeklsrdVNRLEEEVKEWKNRYIR 543
                 *999999887766666555543333333220.....................1334444445556667777777888888889***************9 PP

  Fmp27_WPPW 285 hniqlk 290
                  + ql+
  EEA20908.1 544 AKTQLR 549
                 888886 PP

>> EzrA  Septation ring formation regulator, EzrA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4  13.6     0.016        18      96     179 ..     364     446 ..     356     459 .. 0.86
   2 ?    9.9  20.6   0.00016      0.18     305     432 ..     413     550 ..     407     557 .. 0.88

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.016
                 HHHTTHHHHHHHHHHHHHHHHHHHHHHHHTHHHHTTTTTHHHHHHHHHHHHHHHHT--TTTTHHHHHHHHHHHHHHHH------ CS
        EzrA  96 fkkakkklaeleeeldeveekikkileelkelteseeknreeieklkekYrelrkkllanrfsygealeelekqleniekefse 179
                 + ++++++a+l+e++de+++ +k+  ee++ l++ +ek +++ ++ +++ + ++ +l+++  + ++a ++l+++++++++e + 
  EEA20908.1 364 LADSQAQVATLQERVDELQSLMKNKDEEISRLQDEQEK-SQISTSERDEWEGVKSELENKLTDVENANTYLQNKIDQMQEEHAM 446
                 567889999**********************9876555.67788889******************************9998665 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.00016
                 TTTSSSSSHHHHT--HHHHTTGGG-TTTS-GGGSSTTTSTTH..........HHHHHHHHHHHHHHHHHHHHHS-SS---STTGGGTHHHHHHHHHHHH CS
        EzrA 305 eknlkelkeklehlekqnkelkeeldrlkqsYeLseeelekl..........relekelkelekdyeeleekleekkvaYSelqeeleeleekleeiee 393
                 e   +el++kl+ +e+ n+ l++++d+++++  ++e+el k+           el+++ +ele+++++l+ +l+e++ +  e++ +  ++ +++ +++e
  EEA20908.1 413 EGVKSELENKLTDVENANTYLQNKIDQMQEEHAMKEQELRKQieaahgagvhVELQQRYSELETRHKSLQSELQEQQKTTEEVRRDASNFLKEMRAMSE 511
                 566789********************************98862222222222468999***************************************** PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSS CS
        EzrA 394 kqeeileslkslrkdEkrAreqldeikkelkeikrkiek 432
                 + + ++e+ ++l +d +r +e+++e+k++   +k +++ 
  EEA20908.1 512 RSNATWEQEEKLSRDVNRLEEEVKEWKNRYIRAKTQLRH 550
                 ****************************99999988875 PP

>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   2.7   0.00075      0.84      25      58 ..     368     401 ..     367     405 .. 0.92
   2 ?    4.9   3.5     0.024        27      29      61 ..     417     449 ..     415     452 .. 0.88
   3 ?    9.0   1.0    0.0014       1.5      30      60 ..     466     496 ..     463     500 .. 0.91
   4 ?    0.4   1.2      0.63     7e+02      27      60 ..     505     538 ..     503     550 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00075
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  25 qaeieeLerrvkaLekeNksLkseleelkkevek 58 
                 qa+++ L++rv++L++ +k+  +e+++l++e ek
  EEA20908.1 368 QAQVATLQERVDELQSLMKNKDEEISRLQDEQEK 401
                 78999*************************9984 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.024
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  29 eeLerrvkaLekeNksLkseleelkkevekLks 61 
                 +eLe++    e+ N+ L+++++++++e + +++
  EEA20908.1 417 SELENKLTDVENANTYLQNKIDQMQEEHAMKEQ 449
                 58*************************995555 PP

  == domain 3  score: 9.0 bits;  conditional E-value: 0.0014
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  30 eLerrvkaLekeNksLkseleelkkevekLk 60 
                 eL++r ++Le+  ksL+sel+e +k+ e+ +
  EEA20908.1 466 ELQQRYSELETRHKSLQSELQEQQKTTEEVR 496
                 8************************999776 PP

  == domain 4  score: 0.4 bits;  conditional E-value: 0.63
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  27 eieeLerrvkaLekeNksLkseleelkkevekLk 60 
                 e+ + ++r+ a  ++ ++L+  +++l++ev++ k
  EEA20908.1 505 EMRAMSERSNATWEQEEKLSRDVNRLEEEVKEWK 538
                 5666677777777777888888888888888766 PP

>> XLF  XLF-Cernunnos, XRcc4-like factor, NHEJ component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   1.2   5.5e-05     0.062     140     176 ..     371     407 ..     360     413 .. 0.89
   2 ?   -1.6   2.7       2.3   2.6e+03      58      86 ..     467     495 ..     416     535 .. 0.65

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 5.5e-05
         XLF 140 saelkrqveeLieilkeKDavIskLldklessGadls 176
                 +a+l+++v+eL +++k+KD +Is+L d+ e+s +++s
  EEA20908.1 371 VATLQERVDELQSLMKNKDEEISRLQDEQEKSQISTS 407
                 6789************************999987765 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 2.3
         XLF  58 psedeeqlavlleklrkaldgskkssaef 86 
                  +++ ++l+++ ++l+++l++++k+++e+
  EEA20908.1 467 LQQRYSELETRHKSLQSELQEQQKTTEEV 495
                 33333666677777777777777776665 PP

>> ATG16  Autophagy protein 16 (ATG16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   9.2    0.0022       2.5     120     172 ..     359     411 ..     346     422 .. 0.82
   2 ?    0.3  25.0      0.61   6.9e+02      89     183 ..     422     536 ..     417     554 .. 0.44

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.0022
       ATG16 120 edeerlaeleaeraaletklkdreeelrekeklvqdlqDElsaLqlqlnqaEe 172
                  +++ la+ +a++a+l++++++++  ++ k++ +  lqDE +  q+  + ++e
  EEA20908.1 359 GEKKFLADSQAQVATLQERVDELQSLMKNKDEEISRLQDEQEKSQISTSERDE 411
                 566779999*******************************9999999887765 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.61
       ATG16  89 elaelyksrgelaqrllelneelqkleeklkedeerla......eleaeraaletklkdreeelrekeklvqdlqDElsaLqlqlnqaEeklr...... 175
                  l+++  +++ l++++ +++ee++ +e++l+++ e+ +      el+++ ++let+ k+++ el+e++k+ ++++ + s    ++  + e+++      
  EEA20908.1 422 KLTDVENANTYLQNKIDQMQEEHAMKEQELRKQIEAAHgagvhvELQQRYSELETRHKSLQSELQEQQKTTEEVRRDASNFLKEMRAMSERSNatweqe 520
                 455555555555555555555555555555555443322222224555555555555555555555555555554444444444443333333333333 PP

       ATG16 176 ........klekENke 183
                         +le+E ke
  EEA20908.1 521 eklsrdvnRLEEEVKE 536
                 3333333333333333 PP

>> DUF948  Bacterial protein of unknown function (DUF948)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   3.0       4.4   4.9e+03      35      58 ..     371     394 ..     354     467 .. 0.61
   2 ?   12.5   0.3   0.00012      0.14      22      80 ..     479     537 ..     477     541 .. 0.92
   3 ?   -0.2   0.0       1.1   1.2e+03      33      84 ..     806     860 ..     781     864 .. 0.51

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 4.4
      DUF948  35 ieelekqvdpilkevedllakvne 58 
                 +++l+++vd++   +++  +++ +
  EEA20908.1 371 VATLQERVDELQSLMKNKDEEISR 394
                 444444444433333333333333 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 0.00012
      DUF948  22 lklkktldeaaatieelekqvdpilkevedllakvnelledvneklekvdplteavadl 80 
                 ++l++ l+e ++t ee+++++ + lke++++ + +n++ e+ ++ + +v++l e+v+++
  EEA20908.1 479 KSLQSELQEQQKTTEEVRRDASNFLKEMRAMSERSNATWEQEEKLSRDVNRLEEEVKEW 537
                 678999*******************************9999999999999999999886 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 1.1
      DUF948  33 atieelekqvdpilkevedllakvnelledvne...klekvdplteavadlgesv 84 
                 ++i  +++++ +i+  v +++a +   ++  +      e++ p+++++a  ++ +
  EEA20908.1 806 EHISAIRNHISAISIVVGNVVASTDHAMDKAEIspaVRERLGPVVQSLASCSDRL 860
                 3333444444445444445555444444444433334456666666666666555 PP

>> Jnk-SapK_ap_N  JNK_SAPK-associated protein-1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8  21.5    0.0008       0.9      41     155 ..     363     479 ..     361     480 .. 0.73
   2 ?   -0.4  18.4       1.1   1.2e+03      49     147 ..     468     578 ..     447     585 .. 0.61
   3 ?   -1.0   0.0       1.6   1.8e+03      77     120 ..     774     816 ..     769     819 .. 0.72
   4 ?   -1.9   0.0       3.1   3.5e+03      78     102 ..     881     905 ..     848     910 .. 0.67

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.0008
  Jnk-SapK_ap_N  41 lasrneeeeaeleelreeleqLeteyerekelrkrae..eele.eiedqweeerkelqekveqleeenrelelkaknaadqlsrleekeaelkkey 133
                    ++++++++ a+l+e  +el++L +++++e +  ++++   ++     d+we+ ++el++k++++e+ n  l+ k+++++++      ke+el+k+ 
     EEA20908.1 363 FLADSQAQVATLQERVDELQSLMKNKDEEISRLQDEQekSQIStSERDEWEGVKSELENKLTDVENANTYLQNKIDQMQEE---HAMKEQELRKQI 455
                    78999*******************9999986555554222222133599***********************666665544...334445555555 PP

  Jnk-SapK_ap_N 134 sklhe..retellkklkelverqr 155
                    +++h    + el +++ el  r +
     EEA20908.1 456 EAAHGagVHVELQQRYSELETRHK 479
                    555557789999999988877665 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 1.1
  Jnk-SapK_ap_N  49 eaeleelreeleqLeteyerekelrkrae...........eeleeiedqweeerkelqekveqleeenrelelkaknaadqlsrleekeaelkkey 133
                    +++ +el+   ++L++e++++++  ++                e+   +we+e+ +l+  v++leee++e + +   a++ql  l  +     + +
     EEA20908.1 468 QQRYSELETRHKSLQSELQEQQKTTEEVRrdasnflkemrAMSERSNATWEQEE-KLSRDVNRLEEEVKEWKNRYIRAKTQLRHLRTSTVGIPNLH 562
                    344444444444444444444333333333333566444333444555666665.67888888888888888888888888888887777774444 PP

  Jnk-SapK_ap_N 134 sklhe......retellkkl 147
                        +      re+el++++
     EEA20908.1 563 ----TdvgmaaRENELIHEH 578
                    ....3344477888888776 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 1.6
  Jnk-SapK_ap_N  77 eeeleeiedqweeerkelqekveqleeenrelelkaknaadqls 120
                    + elee+   +e++++ l + ++ l   +r  e  ++++ +++s
     EEA20908.1 774 DHELEELKLYLEDQTEGLVQTIQALVASIRGAE-HISAIRNHIS 816
                    567888888888888888888888888888777.6666666665 PP

  == domain 4  score: -1.9 bits;  conditional E-value: 3.1
  Jnk-SapK_ap_N  78 eeleeiedqweeerkelqekveqle 102
                     +l  i  ++ +e+kel  ++ qle
     EEA20908.1 881 AKLPPIAFEIARETKELVHRIDQLE 905
                    4555556667777888888777776 PP

>> Fez1  Fez1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8  16.3      0.06        68      40     138 ..     364     456 ..     354     470 .. 0.44
   2 ?    7.2  12.1    0.0055       6.2      27     114 ..     468     552 ..     462     604 .. 0.75

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.06
        Fez1  40 lrelrakleekeeeikeleesleektlelevcenelqrkkseaellrekvekleeelkelreelselsleeeeaalesdeakaqrqeaeeleelkreve 138
                 l + +a++ + +e+++el++ +++k++e+ ++++e ++++ +++  r++ e +++el++  +++++++     + l+ +  ++q+++a + +el++++e
  EEA20908.1 364 LADSQAQVATLQERVDELQSLMKNKDEEISRLQDEQEKSQISTSE-RDEWEGVKSELENKLTDVENAN-----TYLQNKIDQMQEEHAMKEQELRKQIE 456
                 445566666666666666666666666666666665555333332.2223333333332222222211.....11222222222233333333333333 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0055
        Fez1  27 tqklseivalkaqlrelrakleekeeeikeleesleektlelevcenelqrkkseaellrekvekleeelkelreelselsleeeeaa 114
                  q+ se   l ++ + l+++l+e++++++e++  +++  +e+  + ++ + + +++e l+  v++leee+ke ++++ +++++ ++ +
  EEA20908.1 468 QQRYSE---LETRHKSLQSELQEQQKTTEEVRRDASNFLKEMRAMSERSNATWEQEEKLSRDVNRLEEEVKEWKNRYIRAKTQLRHLR 552
                 555554...78999******************************999999998777777777************98877665554444 PP

>> HisKA_3  Histidine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0     0.047        53      26      62 ..      84     120 ..      81     125 .. 0.89
   2 ?    6.6   0.8    0.0098        11      24      61 ..     474     511 ..     471     516 .. 0.91

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.047
                 HHHHHTTT-HHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
     HisKA_3  26 lakrllekdpekaaeqlreieelarealqevRrllhn 62 
                 +a+ ++ + p++   + r++ee + + ++ vRr+l+n
  EEA20908.1  84 AARSSVGTLPDQQGGRYRRMEESLAQHYNAVRRFLGN 120
                 67788899999***********************987 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0098
                 HHHHHHHTTT-HHHHHHHHHHHHHHHHHHHHHHHHHHH CS
     HisKA_3  24 lelakrllekdpekaaeqlreieelarealqevRrllh 61 
                 le+ +++l+++ ++ +++ +e+++ a++ l+e+R++++
  EEA20908.1 474 LETRHKSLQSELQEQQKTTEEVRRDASNFLKEMRAMSE 511
                 7788899999999**********************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (915 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2188  (0.122037); expected 358.6 (0.02)
Passed bias filter:                      585  (0.0326287); expected 358.6 (0.02)
Passed Vit filter:                       145  (0.00808746); expected 17.9 (0.001)
Passed Fwd filter:                        90  (0.0050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              16  [number of targets reported over threshold]
# CPU time: 1.56u 0.36s 00:00:01.92 Elapsed: 00:00:00.58
# Mc/sec: 4748.99
//
Query:       EEA20909.1  [L=1059]
Description: DNA excision repair protein (Rad26L), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.5e-51  174.4   0.1    3.7e-51  173.9   0.1    1.2  1  SNF2_N         SNF2 family N-terminal domain
    3.3e-25   88.0   0.9      1e-24   86.4   0.9    1.9  1  VIGSSK         Helicase-associated putative binding domain, C
    7.7e-21   74.5   0.0    1.5e-18   67.2   0.0    3.4  3  Helicase_C     Helicase conserved C-terminal domain
    1.9e-07   30.5   0.0    4.5e-07   29.3   0.0    1.6  1  ERCC3_RAD25_C  ERCC3/RAD25/XPB C-terminal helicase
    1.4e-06   28.4   0.1      7e-06   26.1   0.0    2.3  3  ResIII         Type III restriction enzyme, res subunit
     0.0048   16.7   0.0      0.011   15.5   0.0    1.5  1  DEAD           DEAD/DEAH box helicase


Domain annotation for each model (and alignments):
>> SNF2_N  SNF2 family N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  173.9   0.1   1.3e-54   3.7e-51      55     321 ..     265     536 ..     251     580 .. 0.83

  Alignments for each domain:
  == domain 1  score: 173.9 bits;  conditional E-value: 1.3e-54
                 T--EEE---TTS--HHHHHHHHH...HHTTTS---.......S-........EEEE--HHHHHHHHHHHHHH-TTS-EEE--SSHHHH----------- CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      SNF2_N  55 vrGGiLaDemGLGKTvqvlalilaqrakeekdkekkrkdtlagp........tLivvPaslldqWeneierhvsssalrvlvyggqkkmkkkntkvapk 145
                 ++GGiL D+mGLGKTvqv+a+++a   k  +++ +kr ++l+          tLiv+P +l+++W++e++r+     + v++++       k++ ++++
  EEA20909.1 265 QKGGILGDDMGLGKTVQVIAFLTAAYGKTGDERDMKRMRKLRRSgdnvwypcTLIVCPGTLIENWKSELQRWGWWA-VGVFHGDR------KEEALQAA 356
                 47*********************77755555555555555555556667777********************7665.55555544......4568899* PP

                 ------EEEE-HHHHHHHT......TTS-S-S-SEEEES-GGGT--TTSHHHHHHHH---S-EEEE-S--SSS-HHHHHHHHHHH-TTTT--HHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      SNF2_N 146 lladydvvittYdvlsreaelqkkrsvlkqvewkrvvlDEghtlknstskaaeavskLstsnrwiltGTPiqnsledlygLlkfLreepfgekqtfdkl 244
                  +   +++ittY +++ ++      ++++ vew++vv DE+h++k  +s+++ a++++++  r+ ltGT iqn+ e+l++Ll+  +++++g  + +++ 
  EEA20909.1 357 KAGRLEILITTYVTYRMNK------DAINMVEWDCVVADECHQIKERKSETTIAMNEINALCRIGLTGTAIQNKYEELWTLLNWTNPGKLGPVTAWKRA 449
                 ****************766......************************************************************************** PP

                 THHHHH............HHHHHHHHHHHT.T-STTEE---GGGT--S---EEEEEEEEE--HHHHHHHH.................... CS
                 xxxxxx............xxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      SNF2_N 245 lqrpie............aqaekgrsrLlq.llqrlmlrrakkdveknlPpkteeiiflklskverksYnrllevlrkkalakllkrsea 321
                 + +p +            ++a+k +++L+q ll ++ lrr+k+ +  +lP+k+ +++f++l++ ++ +Y+   ++l  +al  +++ se+
  EEA20909.1 450 VADPLKigqshdatlyqlSKARKTAKKLVQnLLPEFFLRRMKTLIADQLPKKSDRVVFCPLTDTQADAYE---NFLNSDALVYIKNASEM 536
                 *****************988899999988736778***********************************...55555555555555444 PP

>> VIGSSK  Helicase-associated putative binding domain, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.4   0.9   3.5e-28     1e-24       1      62 []     864     928 ..     864     928 .. 0.95

  Alignments for each domain:
  == domain 1  score: 86.4 bits;  conditional E-value: 3.5e-28
      VIGSSK   1 sqlaalitaeakekkkeakks...tkkksDaiqAILasaGVeYTHenseViGsSkvEeqLsrrAe 62 
                 sq+aali++++ ++++++ +s   ++kk+D+i+AILa+aGVeY+H n+eViGsSkvEe+LsrrAe
  EEA20909.1 864 SQIAALIRGDTPSSTTATTTSslqESKKHDPIHAILAGAGVEYSHLNNEVIGSSKVEERLSRRAE 928
                 89********999999888878889***************************************7 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0      0.14   4.3e+02      53      76 ..     347     370 ..     317     413 .. 0.82
   2 !   67.2   0.0     5e-22   1.5e-18       2     111 .]     627     739 ..     626     739 .. 0.91
   3 ?    1.1   0.0      0.16   4.8e+02      39      70 ..     999    1030 ..     958    1038 .. 0.75

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.14
                 HHHHHHHHHHHTTSSSEEEESGGG CS
  Helicase_C  53 nereeileqfnkgesdvLiatdva 76 
                 + +ee+l++ ++g+  +Li+t v 
  EEA20909.1 347 DRKEEALQAAKAGRLEILITTYVT 370
                 678999***************884 PP

  == domain 2  score: 67.2 bits;  conditional E-value: 5e-22
                 HHHHHHHHH.HHTTTTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHH..TTSSSEEEESGGGTSSSTSTTESEEEESSSSSSH CS
  Helicase_C   2 kleallell.kleeeggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfn..kgesdvLiatdvaerGidipkvnlVinfdlprnv 97 
                 k++ l +ll   +++g+k+l+f+++++ l+++++l ++ +++v +l+g ++ ++r +++++fn   +++ +Li+t++++ G++i ++n V+ +d+ +n+
  EEA20909.1 627 KWKVLRKLLkWWHANGDKVLVFSHSVRLLKMLQMLFNHTSYNVSYLDGAMSYEDRAKVVDEFNsdPQQFVFLISTRAGGVGLNIVSANKVVVVDPNWNP 725
                 677888888777899************9977788877779***********************7556677***************************** PP

                 HHHHHHHTTSSSTT CS
  Helicase_C  98 tsyiqriGRtgRag 111
                 ++  q+ +R++R+g
  EEA20909.1 726 SHDLQAQDRAYRIG 739
                 ************97 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.16
                  TTSTEEEESTTSTHHHHHHHHHHHHTTSSSEE CS
  Helicase_C   39 kgikvavlhgelpqnereeileqfnkgesdvL 70  
                  ++ ++a +   ++q +r++ le++ ++++ +L
  EEA20909.1  999 NATEFALVVEGMTQAQRRACLERWYRDRREML 1030
                  36777778888***********9987776666 PP

>> ERCC3_RAD25_C  ERCC3/RAD25/XPB C-terminal helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.3   0.0   1.5e-10   4.5e-07      38     135 ..     617     723 ..     603     788 .. 0.78

  Alignments for each domain:
  == domain 1  score: 29.3 bits;  conditional E-value: 1.5e-10
  ERCC3_RAD25_C  38 lyvmnpn...kfracefLikyhekrgDkiivfsDnvfaLkeyakkl.....kkpyiyGetseaerlkilqkfkknpkvntifls.kvgDtsiDlPe 124
                    +   np+   k++++  L+k+ ++ gDk++vfs +v  Lk + + +     +  y+ G++s ++r k++++f+++p+  + ++s + g   +++ +
     EEA20909.1 617 INYANPEfcgKWKVLRKLLKWWHANGDKVLVFSHSVRLLKMLQMLFnhtsyNVSYLDGAMSYEDRAKVVDEFNSDPQQFVFLIStRAGGVGLNIVS 712
                    5566775555999************************99998766511111568*********************9988877774789999***** PP

  ERCC3_RAD25_C 125 anvliqisshf 135
                    an ++ ++ + 
     EEA20909.1 713 ANKVVVVDPNW 723
                    *9999887664 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.1   0.0   2.4e-09     7e-06       4     169 ..     247     420 ..     245     422 .. 0.82
   2 ?   -3.9   0.0       3.9   1.2e+04      48      78 ..     634     666 ..     626     691 .. 0.69
   3 ?   -3.2   0.2       2.4   7.2e+03      64     111 ..     762     815 ..     758     840 .. 0.52

  Alignments for each domain:
  == domain 1  score: 26.1 bits;  conditional E-value: 2.4e-09
                 E-HHHHHHHHHHT......TTSEEEEEESTTSTHHHHH.HHHHHHH-S.......................-EEEEESSHHHHHHHHHHGGGGTGG... CS
      ResIII   4 lreyQeeaienlleklkskrdkrglikmaTGtGKTlva.aklierllkkgkee..................kflflvprkslleqtleefkkflseayk 83 
                 lr+yQ e    l + +    +k g++    G GKT+   a l++++ k g+e+                   +l+++p+ +l+e +++e++++   a+ 
  EEA20909.1 247 LRDYQVEGAAFLHKLF--VYQKGGILGDDMGLGKTVQViAFLTAAYGKTGDERdmkrmrklrrsgdnvwypCTLIVCPG-TLIENWKSELQRWGWWAV- 341
                 6888888776665555..6999999999********88456666666666655*****************667777776.799***********9975. PP

                 .GEEEESSS-B--.........-SEEEEEHHHHHHTH........HHHTTT-SEEEEETGGGTTS.TTTHHH.HHT---SEEEEEESS- CS
      ResIII  84 eigkkvsgdkkka..kekdstnkkilvttiqsldadseeeeeeseellrdrfdviiiDEaHrlgakkswrei.lekfkeavllglTATp 169
                    ++++gd+k++  ++ ++   +il+tt+ +   ++       +     + d+++ DE+H +++ ks + i ++ +++ +++glT+T 
  EEA20909.1 342 ---GVFHGDRKEEalQAAKAGRLEILITTYVTYRMNK-------DAINMVEWDCVVADECHQIKERKSETTIaMNEINALCRIGLTGTA 420
                 ...6666666666677789999********9988888.......667778999************987777669999**********95 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 3.9
                 H-S.......-EEEEESSHHHHHHHHHHGGGGT CS
      ResIII  48 llkkgkee..kflflvprkslleqtleefkkfl 78 
                 llk+ + +  k+l++ ++  ll+ ++  f++++
  EEA20909.1 634 LLKWWHANgdKVLVFSHSVRLLKMLQMLFNHTS 666
                 444434334499999999999988777666554 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 2.4
                 HHHHHHHHHHGGGGTGG.......GEEEESSS-B--..........-SEEEEEH CS
      ResIII  64 kslleqtleefkkflseayke...igkkvsgdkkka...kekdstnkkilvtti 111
                 +++++q + ++   +s+++     +++k++++++++   +  + +n++i++  i
  EEA20909.1 762 RQIYKQQQANIGYNASTERRYfkgVQEKKDQKGEIFglsNLFEYQNNNIVLRDI 815
                 566677666553333333221223333333333333444333566666666554 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   3.8e-06     0.011      22     149 ..     273     408 ..     258     427 .. 0.75

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 3.8e-06
                 STTSSHHHHHHHHHHHHHHHSTTSTS....................-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTT.CS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxx....................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xx RF
        DEAD  22 eTGsGKTlaflipvlqivyetkgktg....................pkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldng.vd 99 
                 + G GKT   +i+ l + y +   tg                    p +liv+P   L+e+  ++l++++      ++ +++g+++++ l++ ++g ++
  EEA20909.1 273 DMGLGKTVQ-VIAFLTAAYGK---TGderdmkrmrklrrsgdnvwyPCTLIVCPG-TLIENWKSELQRWGWW----AVGVFHGDRKEEALQAAKAGrLE 362
                 569999987.55555555543...2233355566677777788887999999996.699*********9996....234678899999999998778** PP

                 EEEEEHHHHHHHHHCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD 100 ivvgtpgrlddllstgklnlsqvrflVlDEadrlldqgfsdfinrilnql 149
                 i+++t       +++  +n+ +  ++V DE++++ + + + +i    n++
  EEA20909.1 363 ILITTYVTYR--MNKDAINMVEWDCVVADECHQIKERKSETTIAM--NEI 408
                 *****95555..588999*****************9966655543..555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1059 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1214  (0.0677115); expected 358.6 (0.02)
Passed bias filter:                      614  (0.0342462); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.83u 0.32s 00:00:01.14 Elapsed: 00:00:00.46
# Mc/sec: 6911.43
//
Query:       EEA20910.1  [L=283]
Description: exosome complex endonuclease 1/ribosomal RNA processing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.5e-35  121.4   0.5    6.7e-35  120.5   0.5    1.5  1  RNase_PH  3' exoribonuclease family, domain 1


Domain annotation for each model (and alignments):
>> RNase_PH  3' exoribonuclease family, domain 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  120.5   0.5   3.7e-39   6.7e-35       1     132 []      23     153 ..      23     153 .. 0.93

  Alignments for each domain:
  == domain 1  score: 120.5 bits;  conditional E-value: 3.7e-39
                 EEEEEEEEESSSSTTSEEEEEEECCEEEEEEEEEEEEEE-TCCG--CCEEEECCCCECCCCEC-C....S...HHHHHHHHHHHHHHCCTC-CCGCCTC CS
    RNase_PH   1 elRslsietgvlsqanGSaylelGdtkvlasvtgpieerpseerddaegaldveveyapfasger.rregrpsdeeielsrlleralrpsillekkpks 98 
                 elR l++++ + ++++GS+yl++G+t+++++v+gp e++++ + +  e ++dv+v++a fa ++r rr g  ++++++ls +l++a+++ ++++ +p+s
  EEA20910.1  23 ELRLLQAQISTNPASSGSSYLSMGNTSIMCTVHGPHETSGAGS-SATEAVVDVDVNIAGFAGVDRkRRAGGSDRQSTQLSTALKSAFQSHLHTSLYPHS 120
                 7999*********************************966666.433455***************555599999999********************** PP

                 EEEEEEEEEECCCS-CHHHCHHHHHHHHHCTCEE CS
    RNase_PH  99 tididitvlssdggslldalinaaslALadagip 132
                 ti + + vlssdg sl++a+ina++lAL+dagip
  EEA20910.1 121 TITVQVSVLSSDG-SLFAAAINACTLALVDAGIP 153
                 *************.*******************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (283 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       342  (0.0190752); expected 358.6 (0.02)
Passed bias filter:                      274  (0.0152825); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.22s 00:00:00.67 Elapsed: 00:00:00.39
# Mc/sec: 2189.64
//
Query:       EEA20911.1  [L=234]
Description: cyclophillin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.5e-46  156.1   0.2    1.2e-45  155.6   0.2    1.1  1  Pro_isomerase  Cyclophilin type peptidyl-prolyl cis-trans iso


Domain annotation for each model (and alignments):
>> Pro_isomerase  Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  155.6   0.2   6.7e-50   1.2e-45       6     148 ..      80     223 ..      77     232 .. 0.86

  Alignments for each domain:
  == domain 1  score: 155.6 bits;  conditional E-value: 6.7e-50
  Pro_isomerase   6 tsskGrivieLfadkaPktvenFlklvkeg.........fYdgttFhRvikgfmvqgGdptgktsageqe.kkggesiraipdEitsklkh.krGa 90 
                    t+  Gr++++L++d +P t++nF +l+ +g         +Y+g++FhRvi++fm+qgGd+t ++  g++  +  g   ++++dE+ +k++h ++G+
     EEA20911.1  80 TK-TGRVEFKLYDDVVPRTAKNFAELC-KGftdetgkllTYKGSSFHRVIPQFMLQGGDFTRGN--GTGGkSIYG---EKFADEN-FKIRHeRPGL 167
                    53.8***********************.67788899999********************99984..443323333...69*****.88899789** PP

  Pro_isomerase  91 lamartgkepnsagsqFfItlkeaphldgkytvFGkVveGmdvvekiekvetdeerpk 148
                    l+ma++g  pn++gsqFfIt+ ++++ldgk++vFG+Vv+G+d+ve+iek+ t++  +k
     EEA20911.1 168 LSMANAG--PNTNGSQFFITTVTTSWLDGKHVVFGEVVKGYDIVEAIEKLGTSSGSVK 223
                    *****98..8***************************************877763443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (234 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       331  (0.0184617); expected 358.6 (0.02)
Passed bias filter:                      278  (0.0155056); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.39
# Mc/sec: 1820.72
//
Query:       EEA20912.1  [L=414]
Description: high osmolarity glycerol pathway protein Nbp2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-11   43.8   0.0    4.1e-11   42.3   0.0    1.8  2  SH3_1     SH3 domain
    4.3e-09   36.1   0.0    8.9e-09   35.1   0.0    1.6  1  SH3_9     Variant SH3 domain
    2.5e-07   30.3   0.0    5.3e-07   29.2   0.0    1.6  1  SH3_2     Variant SH3 domain


Domain annotation for each model (and alignments):
>> SH3_1  SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.3   0.0   6.8e-15   4.1e-11       1      47 [.     295     341 ..     295     342 .. 0.98
   2 ?   -2.1   0.0      0.49   2.9e+03       9      21 ..     380     392 ..     378     394 .. 0.84

  Alignments for each domain:
  == domain 1  score: 42.3 bits;  conditional E-value: 6.8e-15
                 EESSSBEXSSTTBXEBSTTEEEEEEEECSSSEEEEEETTSTEEEEEE CS
       SH3_1   1 iAlYDYeaeesdELsfkkGDviivleksedgWwkgrlkgtgkeGliP 47 
                 +Al+D++ e+++EL++k+G vi v+ ++  gW+ +++ +tg+ Gl+P
  EEA20912.1 295 VALFDFTREHENELPLKEGQVILVSYRHGQGWLVAEDPRTGESGLVP 341
                 7********************************************** PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.49
                 SSTTBXEBSTTEE CS
       SH3_1   9 eesdELsfkkGDv 21 
                 e+++ Ls ++G++
  EEA20912.1 380 ESPSNLSAEQGET 392
                 57999******97 PP

>> SH3_9  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.1   0.0   1.5e-12   8.9e-09       1      48 [.     296     345 ..     296     346 .. 0.94

  Alignments for each domain:
  == domain 1  score: 35.1 bits;  conditional E-value: 1.5e-12
       SH3_9   1 AlypyepreddeLsLqrGDvitvieesedgWlegs..ltGrtGlvPanyv 48 
                 Al++++  ++ eL+L +G+vi+v+ ++  gWl ++  +tG++GlvP+ +v
  EEA20912.1 296 ALFDFTREHENELPLKEGQVILVSYRHGQGWLVAEdpRTGESGLVPEEFV 345
                 89**********************999********666*********998 PP

>> SH3_2  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.2   0.0   8.9e-11   5.3e-07       2      55 ..     294     346 ..     293     348 .. 0.89

  Alignments for each domain:
  == domain 1  score: 29.2 bits;  conditional E-value: 8.9e-11
                 EEESS-B-SCGCCB--B-TTEEEEEE..EEEECTTEEEEEE...CCCEEEEEGCGEE CS
       SH3_2   2 vraiedyvgedkseLsfkkGdvikvlslgskdsdgwwegev...gGrvGlfPsslve 55 
                 ++a++d+++e ++eL +k+G+vi v      + + +w+++     G  Gl+P ++v+
  EEA20912.1 294 AVALFDFTREHENELPLKEGQVILVS----YRHGQGWLVAEdprTGESGLVPEEFVR 346
                 79***********************7....777788999886767999*******98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (414 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       511  (0.0285013); expected 358.6 (0.02)
Passed bias filter:                      293  (0.0163422); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2960.40
//
Query:       EEA20913.1  [L=607]
Description: poly(A) polymerase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.5e-23   82.9   0.4    1.1e-13   51.7   0.6    2.4  2  PolyA_pol        Poly A polymerase head domain
    0.00011   21.9   0.0    0.00025   20.7   0.0    1.7  1  PolyA_pol_RNAbd  Probable RNA and SrmB- binding site of polym


Domain annotation for each model (and alignments):
>> PolyA_pol  Poly A polymerase head domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.8   0.0   1.5e-10   1.3e-06       1      41 [.      78     119 ..      78     156 .. 0.73
   2 !   51.7   0.6   1.3e-17   1.1e-13      44     126 .]     173     258 ..     141     258 .. 0.80

  Alignments for each domain:
  == domain 1  score: 28.8 bits;  conditional E-value: 1.5e-10
                 EEEETHHHHHHHTT---CEEEEEEC.S-HHHHHHHHHHHHT- CS
   PolyA_pol   1 lylvGGaVRDlllgkepkDvDlatd.aapeelakllrkkvke 41 
                 +++vGG+VRD+llg+++ D+D+a++ +++ e+a+ l++ ++ 
  EEA20913.1  78 MWFVGGWVRDKLLGNQSCDIDVAMSnMTGPEFASHLKDFLSS 119
                 589*******************98636777777766655444 PP

  == domain 2  score: 51.7 bits;  conditional E-value: 1.3e-17
                 EEETTTTCCCCEECCEEEEECCEECEEEEEE---SSHH..H...HHHHHHCTSSBGGGS-EEECTTTCEE-TTS.HHHHHHTTEE- CS
   PolyA_pol  44 lsgeefqtiavlekkqllevatfRlekdesdarnpese..kstesleeDlkrRDftiNalaynlnkgkvlDlfg.GikdLkskvir 126
                 ++g++ qt  +++   ++++  +R+e++e +++n +++  ++ +s+eeD++rRD t+Na++ynl++++v+D++  G++dL+ kv+r
  EEA20913.1 173 KKGKHLQTTSAKIFGLDIDFVNLRTETQELQVENLSRVgrEFGSSAEEDAYRRDATVNAIFYNLDTQRVEDYTTkGLQDLEAKVLR 258
                 34677777777777778999999999999999998876225566****************************977********997 PP

>> PolyA_pol_RNAbd  Probable RNA and SrmB- binding site of polymerase A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.7   0.0   2.8e-08   0.00025       1      57 [.     285     345 ..     285     351 .. 0.80

  Alignments for each domain:
  == domain 1  score: 20.7 bits;  conditional E-value: 2.8e-08
  PolyA_pol_RNAbd   1 gFtIep.eTaaair..klaplL.kkispeRifeEllKlLlsghpeaglelLretgLlkylf 57 
                      gFtI++ +T++a++  +  +l+ ++ispeRi  El K+ ++++p+ +l    +++L+k++f
       EEA20913.1 285 GFTIDEgDTQQAMKspEIQSLIgTRISPERIGLELKKMVTGPDPVTALLWIHRLKLYKHVF 345
                      5777655677777622344455479**********************************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (607 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       521  (0.0290591); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.42
# Mc/sec: 4330.50
//
Query:       EEA20914.1  [L=442]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        2.1    8.5   6.4       0.98    9.5   0.4    2.6  2  BTP       Chlorhexidine efflux transporter


Domain annotation for each model (and alignments):
>> BTP  Chlorhexidine efflux transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   1.1     0.033   5.9e+02      17      38 ..       8      29 ..       6      31 .. 0.87
   2 ?    9.5   0.4   5.4e-05      0.98      12      47 ..     291     326 ..     289     330 .. 0.95

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.033
         BTP 17 lllllvpllawllgvslleagv 38
                l+l++++l++++  +s++ea+ 
  EEA20914.1  8 LVLVTTLLASLAHAHSWVEALS 29
                7899999999*99****99986 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 5.4e-05
         BTP  12 lFElglllllvpllawllgvslleagvldiglslfa 47 
                 +FE ++ +++vp +++++ v++  ++  +++ s+fa
  EEA20914.1 291 VFESLAATMTVPPVSAIVPVNITASVSYSVAASMFA 326
                 7**********************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (442 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       601  (0.0335211); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.24s 00:00:00.76 Elapsed: 00:00:00.40
# Mc/sec: 3344.29
//
Query:       EEA20915.1  [L=1127]
Description: HMG-CoA reductase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.5e-139  465.1   8.4   1.9e-139  464.7   8.4    1.1  1  HMG-CoA_red     Hydroxymethylglutaryl-coenzyme A reductase
    2.6e-46  157.3   0.0    4.8e-46  156.5   0.0    1.5  1  HPIH            N-terminal domain with HPIH motif
    2.2e-14   53.6   4.2      6e-14   52.2   4.2    1.8  1  Sterol-sensing  Sterol-sensing domain of SREBP cleavage-activ
    1.3e-09   36.7   1.1    1.5e-09   36.5   0.1    1.5  2  Patched         Patched family


Domain annotation for each model (and alignments):
>> HMG-CoA_red  Hydroxymethylglutaryl-coenzyme A reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  464.7   8.4  4.3e-143  1.9e-139       2     367 .]     707    1090 ..     706    1090 .. 0.96

  Alignments for each domain:
  == domain 1  score: 464.7 bits;  conditional E-value: 4.3e-143
                   HHHHHHHHHH.......S-HHHHHHHTT----.HHHHHHHSSS---------EEEEEEEETTEEEEEEE---STTHHHHHHHHHHHHHHTT-B.EE CS
  HMG-CoA_red    2 veeRrkllee.......lteeeleelkeesld.eevadkmiEnviGyvqlPlGvagpllingkeylvPmAteEgslvAsasrgakainesgGvktt 89  
                   v++Rr+++++        +  e++ +++++++ + v+++++EnviGy++lPlGvagp++i+g++y++PmAt+Eg lvAs+srgakain++gG+ t+
   EEA20915.1  707 VKIRRAVVSRtpataavASSLETSLVPYKDYNyTLVHGACCENVIGYLPLPLGVAGPMVIDGQNYFIPMATTEGVLVASTSRGAKAINAGGGAVTV 802 
                   788999997765444333444444479999*99*************************************************************** PP

                   EE----EEEEEEEE.--S-HHHHHHHHHTHHHHHHHHHHCSHHCCT-EEEEEEEEE-SSEEEEEEEEE-TTC--HHHHHHHHHHHHHHHHHH..HT CS
  HMG-CoA_red   90 vlkdgmtraqvvllesvedaaelkkwiekkeeleelanaaestsrggglkdievvlagrlvvlrlkvdtgDAmGaNmvnkateaaaelieee..fg 183 
                   v  dgmtr++ v ++++++aae+k+w++++e    ++ a++stsr+++l++++++lag+++++r+k++tgDAmG+Nm++k++e+a+e++ +e  f+
   EEA20915.1  803 VHGDGMTRGPGVSFPTLTRAAEAKTWLDSEEGASIMRTAFNSTSRFARLQHLKTALAGTNLYIRFKTTTGDAMGMNMISKGVEKALEVMANEcgFD 898 
                   ******************************************************************************************996677 PP

                   SEEEEEEE-S--GGGEEEEEEEEEHHHH..-SSTTHHHHHHHHHHHHHHHHHH-HHHH....HHHHHHH........HHHHHHHHHHTT--HHHHH CS
  HMG-CoA_red  184 eeellsilsNlctdkkasainaiegrgksvvaeatigeevvekilkasaealvdlnra.n.igtankGi.ggfnahaaNgiaAvflAtGqDlaave 276 
                   +++++s+++N+ctdkka+ain+i+grgksvvaea+i+ ++v+++lk s++a+v+ln++ n ig+a++G+ ggfnaha+N+++AvflAtGqD+a+++
   EEA20915.1  899 DMNVISLSANYCTDKKAAAINWIDGRGKSVVAEAIIPGDIVKSVLKSSVDAMVELNISkNlIGSAMAGSlGGFNAHASNIVTAVFLATGQDPAQNV 994 
                   8*********************************************************************************************** PP

                   HHHHHHTTSEEETTTEEEEEEEEE.----SBSHHHHH-HHHHHHHHTT---HH.........HHHHHHHHHHHHHHHHHHHHHT-----HHHHHHH CS
  HMG-CoA_red  277 esshaiaaleevedgdlygsvtlPsleVGtvGGgtklppqaellkllgvkgak......nakeLaeiiaavgLAqelsalrALaaeglqkgHmklh 366 
                   ess++i+++++  dg+l++sv++Ps+eVGt+GGgt l++q+++l++lgv+g++      n+++La+i+aa +LA+els+++ALaa++l+k+Hm+++
   EEA20915.1  995 ESSNCITLMKNL-DGNLHISVSMPSIEVGTIGGGTILEAQSAMLEMLGVRGPHptnpgeNSRQLARIVAASVLAGELSLCAALAAGHLVKAHMAHN 1089
                   ************.777*******************************************************************************9 PP

                   H CS
  HMG-CoA_red  367 r 367 
                   r
   EEA20915.1 1090 R 1090
                   7 PP

>> HPIH  N-terminal domain with HPIH motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  156.5   0.0   1.1e-49   4.8e-46       1     156 []      26     170 ..      26     170 .. 0.93

  Alignments for each domain:
  == domain 1  score: 156.5 bits;  conditional E-value: 1.1e-49
        HPIH   1 kvtkllaslskfaakhPIhtIvvvallasttYlsvleeslfdwkldsksissagkvdvdsLlegsrhlrlgeetawkWqvldseeaaslsakdaqhlaL 99 
                 k+t+ l++++++a+ hPIhtI v+allasttY+++le+s+fd      ++  +g++d  sLl+gsr+lrlge+taw+Wq++d+  +   s+  +qhlaL
  EEA20915.1  26 KITSTLQAVARRACAHPIHTIGVIALLASTTYVGLLEGSIFD------AKGGSGQLDPASLLHGSRNLRLGESTAWRWQLEDKVVSDP-SE-ITQHLAL 116
                 689***************************************......66789*****************************963333.33.57***** PP

        HPIH 100 ltLvFpdsnstssataPelenvplpsnlsaylLpstpnllselssdsslafrlpydq 156
                 +t+vF+ds+s++    P+++++p+p+n+sa ++p+tpnl+s++ +dss+a ++pyd+
  EEA20915.1 117 TTFVFSDSTSSN---TPTIDDIPIPENVSAVHVPQTPNLFSSFLRDSSIALAVPYDE 170
                 *******98855...5**************************************985 PP

>> Sterol-sensing  Sterol-sensing domain of SREBP cleavage-activation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.2   4.2   1.3e-17     6e-14       3     140 ..     258     409 ..     256     420 .. 0.90

  Alignments for each domain:
  == domain 1  score: 52.2 bits;  conditional E-value: 1.3e-17
                     HHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHH.HHHHHHHHHHHHCHHCCHHCHHHHHHHHTTTCH............HHHHHHHHHHHCCC CS
  Sterol-sensing   3 kskfgLglagviivllsvasslgllaylgltltli.ilevlPflvlavgvdnifvlvkavqrtsrslde............seriaealgevgps 84 
                      s+f+L+++ ++  +++ +  l + + lg++++++  +e lPflv+ vg +   +l+kav + s +++             ++ i  a++e+g  
      EEA20915.1 258 GSQFWLAFSVLLSSVFAFLFGLLVTTKLGVSINMLlLSEGLPFLVVTVGFEKPTLLTKAVLSASLKNKAvangnshssrsiQDSIETAIKEEGFG 352
                     69******************************98625799********************999888777788888888888889*********** PP

                     CHHCCCHHHHHHHHHHHCCHH.HHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHH CS
  Sterol-sensing  85 illtsltellalllgaltdvp.avqeFclfaavavlvdFllqitfFvavLsldirre 140
                     i+  +l e++al++ga++ v+ ++++Fc+ aa  +++d +l  tf++++L ++++ +
      EEA20915.1 353 IVRDYLIEITALVIGAVSGVHgGLRQFCFLAAWILFFDCVLLFTFYTSILLIKQEVN 409
                     *******************9946***************************9887654 PP

>> Patched  Patched family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.5   0.1   3.4e-13   1.5e-09     167     405 ..     180     427 ..     173     498 .. 0.76
   2 ?   -3.0   0.1      0.31   1.4e+03     674     700 ..     999    1025 ..     999    1028 .. 0.91

  Alignments for each domain:
  == domain 1  score: 36.5 bits;  conditional E-value: 3.4e-13
     Patched 167 kldeeeveelskeyerelekllkdkyasehievsilhsqiledelqrnaktllpflvvtiaiLlvfsiivsvvlssdalkidwvrskpilailgvlspv 265
                 ++++  +e + +e+++ + k  +   +   +++++    +   +l + a+t+   +++t+  + +  ++vs+ ls+       + s+++la   +ls+v
  EEA20915.1 180 EINDPSTEDDGQEARKWIMKAARGAGSRRALKLYVSDAWSSLVDLIKHAETID-IVIMTLGYISMHLTFVSLFLSM-----RRLGSQFWLAFSVLLSSV 272
                 55666666666666666666666666666666666666655566666666553.2222333333333444444444.....56899************* PP

     Patched 266 lAivsslGlllwlGfrfnsivtv..tPFLvLaiGvDdmflmvaawkrteakls............vkkrigealseagvaitiTslTdvlsFgiGaitt 350
                  A + +l +   lG+  n  ++    PFLv+ +G     l+ +a+   + k++            ++  i+ a+ e g  i+   l ++ +  iGa++ 
  EEA20915.1 273 FAFLFGLLVTTKLGVSINMLLLSegLPFLVVTVGFEKPTLLTKAVLSASLKNKavangnshssrsIQDSIETAIKEEGFGIVRDYLIEITALVIGAVSG 371
                 ****888888889**99988765337*******************9999999999*********99********************************9 PP

     Patched 351 lp.aiqlFciytavailfdfiYqitffaavlaiaakaeaegrhsllliiekeesps 405
                 +  ++  Fc  +a  ++fd +  +tf++++l i +++++ +rh+ +  + +e+  s
  EEA20915.1 372 VHgGLRQFCFLAAWILFFDCVLLFTFYTSILLIKQEVNRIKRHVSIRKALEEDGVS 427
                 86379*************************************99887755444332 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.31
     Patched  674 allfipelitvlvitlsivsidigviG 700 
                  ++ ++ +l   l i +s+ si++g+iG
  EEA20915.1  999 CITLMKNLDGNLHISVSMPSIEVGTIG 1025
                  77899999999***************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1127 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       595  (0.0331865); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.80u 0.26s 00:00:01.06 Elapsed: 00:00:00.45
# Mc/sec: 7561.13
//
Query:       EEA20916.1  [L=611]
Description: acyl-CoA dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.5e-17   62.1   0.1    1.9e-16   60.6   0.1    1.8  1  Acyl-CoA_dh_1  Acyl-CoA dehydrogenase, C-terminal domain
    4.8e-12   46.1   0.0    8.4e-12   45.3   0.0    1.3  1  AidB_N         Adaptive response protein AidB N-terminal doma
    1.7e-10   41.0   0.0    3.5e-10   40.0   0.0    1.6  1  Acyl-CoA_dh_M  Acyl-CoA dehydrogenase, middle domain
  ------ inclusion threshold ------
      0.043   14.1   0.0       0.16   12.2   0.0    2.0  2  Acyl-CoA_dh_2  Acyl-CoA dehydrogenase, C-terminal domain


Domain annotation for each model (and alignments):
>> Acyl-CoA_dh_1  Acyl-CoA dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.6   0.1   4.2e-20   1.9e-16       1     148 [.     311     484 ..     311     486 .. 0.93

  Alignments for each domain:
  == domain 1  score: 60.6 bits;  conditional E-value: 4.2e-20
                    TBHHHHHTTTT--S-----..-SHHHHHHHHHHHHHHHTSB-CC-BGGGSHHHHHHHHHHHHHHHHHHHHHHHHHH--------............ CS
  Acyl-CoA_dh_1   1 gkGfrvametlnheRlavaaaalglarraleealeyarrrkafgkplidhqlvreklaemaaeleaarllvyraaealdagkpd............ 84 
                    g+G++ + + ln +R+ +++ ++g+  r l  ++++ar r   gk l d ++  + la+ +++ +a+  l + +a++l + + +            
     EEA20916.1 311 GQGVKEISHVLNITRMQNIVSSVGAWGRGLAISRAFARVRNVGGKLLCDVPAHVRGLAQEHVKYTAHMHLSFFIAALLGRSEGSndtssaassiip 406
                    6899999*********************************************************************7776666667999******* PP

                    ..........HHHHHHHHHHHHHHHHHHHHHHHHHHGGGTTSGGGH....HHHHHHHTHHHHHSSS-HHHHHHHHHHH CS
  Acyl-CoA_dh_1  85 ..........raeasmaKlfaselaqevadlamqllGgaGyleeyp....verlyrdarvlrigeGtseiqrniiarr 148
                              r  + +aK++++  a +  + +m+ lGg Gyle +     ++rl+rd+ vl i+eGt++i+ ++ +r+
     EEA20916.1 407 qdinrinalyRLLTPIAKAQTALSAINGLRACMESLGGVGYLENEDpelnIARLFRDTNVLAIWEGTTDIMADDFMRV 484
                    *****************************************633333566**********************998876 PP

>> AidB_N  Adaptive response protein AidB N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.3   0.0   1.9e-15   8.4e-12      11     137 ..      20     154 ..      15     177 .. 0.87

  Alignments for each domain:
  == domain 1  score: 45.3 bits;  conditional E-value: 1.9e-15
      AidB_N  11 lfasdpaLqeavaregaaea....aeelaalGellgsaevlelarlanrnpPrlrthDrfGr..RiDevefhpayhalmaaaveaglhasawe.eareg 102
                 ++ +d+aL+ +++ +++  +    ++el ++ e + s+ vl    + +++pP l+   +fG+  R D + +++++++l ++++++g+ a+a+e ++r +
  EEA20916.1  20 QYLEDRALNRIISFHLPTPTpssiSNELLQFSEFVLSKPVLGYIADSEKHPPYLKPLTSFGEenRDDPLVTSEGWRRLQEIGIAEGIVALAYErSERWN 118
                 5889*********99996555566*************************************65599***************************888889 PP

      AidB_N 103 ahvaraallyllaqveaGhlCPltmThAavpaL.ka 137
                  ++++++++ +++     ++CP +mT++a+ +L k+
  EEA20916.1 119 PRIHQFVKYHIWSGSSGIVTCPSAMTDGAAKLLgKH 154
                 9******************************99543 PP

>> Acyl-CoA_dh_M  Acyl-CoA dehydrogenase, middle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.0   0.0   7.8e-14   3.5e-10       3      96 ..     186     301 ..     184     302 .. 0.86

  Alignments for each domain:
  == domain 1  score: 40.0 bits;  conditional E-value: 7.8e-14
                    E---SS-SS-GGG---EEEEETT.E...............EEEEEEEEEEETTTT-SEEEEEEETS-------EEEEEEE....GG.......... CS
  Acyl-CoA_dh_M   3 alTEpqaGsdvasvkttaaerdgge...............yvlnGeKiwitnaaiatlalvlartekpdrarglslflvp..rdap.......... 71 
                    ++TE+++Gsdv++ +t a++ ++ +               ++++G K+  ++a++a+++++la+   +  ++++s f+ p  r             
     EEA20916.1 186 WMTERKGGSDVRGTETIAVKLSDVQsrdggldangqplgpWRVDGFKW-FSSATDANMTILLAK---TG-DNQISAFYAPlrR--Rvanaangkte 274
                    79*************9886655534488899****************5.56788**********...44.689*******642..335788999** PP

                    ..GEEE-----BSS-TTS-EEEEEEE. CS
  Acyl-CoA_dh_M  72 ..gvsvrrieeklGlrglptgelvfed 96 
                      g++++r+++klG++ lpt+e++++ 
     EEA20916.1 275 lnGIKIQRLKNKLGTKALPTAEIEIKG 301
                    ***********************9885 PP

>> Acyl-CoA_dh_2  Acyl-CoA dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0       1.2   5.2e+03       7      22 ..      99     114 ..      97     124 .. 0.84
   2 ?   12.2   0.0   3.5e-05      0.16      75     132 ..     412     473 ..     394     475 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 1.2
                    HHHHHHHHHHHHHHHH CS
  Acyl-CoA_dh_2   7 alGaAraalaefvela 22 
                     +G+A++ +a + e+ 
     EEA20916.1  99 EIGIAEGIVALAYERS 114
                    58******99998875 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 3.5e-05
                    --HHHHHHHHHHHHHHHHHHHHHHHHHHHHCGGGGGBTT-....HHHHHHHHHHHHCTSGGG CS
  Acyl-CoA_dh_2  75 vtvedraearraaalavelaiaavdalfeaaGgsalrkes....plqRlwRDahaaaaHaal 132
                    +++  r+   +a+a ++  ai+  +a++e+ Gg ++++++     + Rl+RD +++a+++++
     EEA20916.1 412 INALYRLLTPIAKAQTALSAINGLRACMESLGGVGYLENEdpelNIARLFRDTNVLAIWEGT 473
                    566677778889999999******************99873333588********9998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (611 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       387  (0.0215851); expected 358.6 (0.02)
Passed bias filter:                      367  (0.0204696); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.43
# Mc/sec: 4298.98
//
Query:       EEA20917.1  [L=296]
Description: transcription/RNA-processing factor Ssu72 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-81  272.0   0.0    2.6e-81  271.8   0.0    1.0  1  Ssu72     Ssu72-like protein


Domain annotation for each model (and alignments):
>> Ssu72  Ssu72-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  271.8   0.0   1.5e-85   2.6e-81       2     191 .]      65     296 .]      64     296 .] 0.98

  Alignments for each domain:
  == domain 1  score: 271.8 bits;  conditional E-value: 1.5e-85
                 EEEEEESSSSSHHHHHHHHHHHTT-EEEEEE-SSSEEEEESSTTSEEEE-T.TS-HHHHHHHHHHHHHHHHHHTSHHHHHHHHHHH-SS--BGGG.... CS
       Ssu72   2 kfavvcasnqnrsmeahkvLkkagfkvkSfGtgsavrLPgpsidkpnvyeF.gtsyeeiyedLkskdkelyeanGllkmldrnrkiKkaPerwqe.... 95 
                  f++vcasn+nrsmeah +L++ +++v+SfGtgs vrLPgpsi++pnv++F +tsy+++yedL +kd++ly++nG+l+mldrnr++K+ Per+q+    
  EEA20917.1  65 IFCTVCASNNNRSMEAHLQLSR-SYPVISFGTGSLVRLPGPSITQPNVFNFdSTSYNHMYEDLYNKDQRLYRNNGILNMLDRNRNLKWGPERFQNwvpg 162
                 59******************85.7***************************99********************************************** PP

                 ................---.--SEEEESSHHHHHHHHHHHHHS--SS-EEEEEEEE---SSHHHHHHHHHHHHHHHHHHHT-SS............... CS
       Ssu72  96 ................aeekkfdvvitceervfdavvedllsreselnrpvhvinvdikDnheeAlvgakaileLakaleeaede.............. 164
                                 +e++++dv+itceer++davv+dll+r+s+lnrpvhv+nvdi+DnheeAl+g+kai +La++l++a++e              
  EEA20917.1 163 qprldhiakgdkgslgTEAGVVDVIITCEERCWDAVVDDLLNRGSPLNRPVHVFNVDIRDNHEEALTGGKAIRDLADMLNAAANEerrlyddpdawdrg 261
                 **************999999*************************************************************99999************* PP

                 .......HHHHHHHHHHHHHHHHT--.EEEEEEEE CS
       Ssu72 165 .......leeevkeilaefeektkkl.llytvafy 191
                        ++e+v+eil +++ek+++l +l+t++++
  EEA20917.1 262 asearqsFDEKVPEILGAWQEKYPNLpALWTLSWF 296
                 *********************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (296 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       419  (0.02337); expected 358.6 (0.02)
Passed bias filter:                      388  (0.0216409); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 1933.89
//
Query:       EEA20918.1  [L=243]
Description: isochorismatase family hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.5e-22   78.5   0.0    3.8e-21   76.0   0.0    2.0  1  Isochorismatase  Isochorismatase family
  ------ inclusion threshold ------
      0.013   15.1   0.0      0.019   14.6   0.0    1.2  1  Ribosomal_S7     Ribosomal protein S7p/S5e


Domain annotation for each model (and alignments):
>> Isochorismatase  Isochorismatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.0   0.0   4.3e-25   3.8e-21       2     173 ..      12     233 ..      11     235 .. 0.85

  Alignments for each domain:
  == domain 1  score: 76.0 bits;  conditional E-value: 4.3e-25
  Isochorismatase   2 alvviDmqndfv.eegvkeseeisavveninkllkaarkagipviftrdvhe............................leevkgdlderkaa 66 
                      al+v+Dmq+df+ ++g  ++e+ + + + i+kll       +  i t+d h+                              + +   ++r ++
       EEA20918.1  12 ALIVVDMQEDFCpPNGSLAVEGGRTIAPLIVKLLNLPA--FVIRIGTQDWHPadhisfasnhpspnnkpfesyigmnnpaPGREHETKRQRLWP 103
                      9************9999999999999999999986432..2223333444445555555555588***********9997666677778889** PP

  Isochorismatase  67 phfkpgttgaelvpelaplegdvvvdKt.......rfsaf...............agtdldeiLkelgiktivlaGiatdvCVeatardaldlG 138
                       h++ +t gae++ e+a   + +++ K+        +s f                + ++ ++Lk+ +++++ ++G+a d+CV+ ta+da++ G
       EEA20918.1 104 IHCVASTKGAEIIAEIASTNKLDILAKKgmdtrveMYSVFsdafqnmdpsmhlksVDVGVAATLKQYNVTDVFVVGLAGDYCVKYTAIDAARAG 197
                      ******************99777777775777777666669999**********9999************************************ PP

  Isochorismatase 139 yevvvvsDAvaalspel.hdaalkrlkqafatvitt 173
                      ++ +vv+DAv +++p + +++alk++ + +++v+ +
       EEA20918.1 198 FRSYVVEDAVRSVDPGEgWAQALKEFGEGGVQVVRS 233
                      **************9999********9999999876 PP

>> Ribosomal_S7  Ribosomal protein S7p/S5e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.0   2.1e-06     0.019      33      86 ..     111     167 ..      99     196 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 2.1e-06
                   TTBHHHHHHHHHHHHHHHHHH...HSS-HHHHHHHHHHHCS-SEEEEEEBSSSSBEE CS
  Ribosomal_S7  33 dGkkslAekivygaldiieek...tkkdplevleeAlenvkPrvevksrrvGGatyq 86 
                   +G   +Ae    + ldi+++k   t+ + ++v+++A +n+ P++ +ks+ vG a+  
    EEA20918.1 111 KGAEIIAEIASTNKLDILAKKgmdTRVEMYSVFSDAFQNMDPSMHLKSVDVGVAATL 167
                   56667788888899999999955445599***********************76654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (243 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       346  (0.0192983); expected 358.6 (0.02)
Passed bias filter:                      329  (0.0183502); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1643.54
//
Query:       EEA20919.1  [L=219]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.3e-40  136.8   0.0      1e-39  136.4   0.0    1.1  1  DUF3605   Protein of unknown function (DUF3605)


Domain annotation for each model (and alignments):
>> DUF3605  Protein of unknown function (DUF3605)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  136.4   0.0   5.6e-44     1e-39       2     130 ..      81     210 ..      80     216 .. 0.94

  Alignments for each domain:
  == domain 1  score: 136.4 bits;  conditional E-value: 5.6e-44
                 HHHHHHHHHHT-GGG----HHHHHHHHHHHHHHT...TS-HHHHHHHHHT-.......STTS.TTSSGGGEEEEE-SS---B-TTEEEEEEEESS---T CS
     DUF3605   2 WeevkeiieeneleklkRspsdlrrYlkfkkelkkkygsiveyilkerlkWee...leakeelpfadeedykillNdfPYgleedivHlvvWsktelee 97 
                 We+vke++++n++ k++R psdlrrYl+++  lk+kygsi++++++erl+W++   l+a++ +pf+ ++d+kil+Nd+PYgle++ivHlv+W+k+elee
  EEA20919.1  81 WEKVKELVRTNDIGKFQRLPSDLRRYLEYMFYLKQKYGSIMDFVVSERLHWDQeggLKARG-QPFECDDDLKILYNDWPYGLEKGIVHLVIWTKFELEE 178
                 ***************************************************7667666666.8************************************ PP

                 T-SS.HHHHHHHHHHHHHHHTHHH.....HT-E CS
     DUF3605  98 deetgdlteesrakieefvkktfvekleeedkv 130
                 d++tg lte++ +ki+++v + f++++  +d+v
  EEA20919.1 179 DPATGLLTESMWKKIDDYVGRVFRSRIP-ADQV 210
                 *************************997.5554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (219 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       294  (0.016398); expected 358.6 (0.02)
Passed bias filter:                      265  (0.0147805); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.44
# Mc/sec: 1493.42
//
Query:       EEA20920.1  [L=156]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      3e-14   53.6   0.0    4.4e-14   53.1   0.0    1.2  1  DUF3605   Protein of unknown function (DUF3605)


Domain annotation for each model (and alignments):
>> DUF3605  Protein of unknown function (DUF3605)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.1   0.0   2.4e-18   4.4e-14       2      64 ..      81     145 ..      80     153 .. 0.85

  Alignments for each domain:
  == domain 1  score: 53.1 bits;  conditional E-value: 2.4e-18
                 HHHHHHHHHHT-GGG----HHHHHHHHHHHHHHT...TS-HHHHHHHHHT-.......STTS.TTS CS
     DUF3605   2 WeevkeiieeneleklkRspsdlrrYlkfkkelkkkygsiveyilkerlkWee...leakeelpfa 64 
                 We+vke++++n++ k++R psdlrrYl+++  lk+kygsi++++++erl+W++   l+a++ +pf+
  EEA20920.1  81 WEKVKELVRTNDIGKFQRLPSDLRRYLEYMFYLKQKYGSIMDFVVSERLHWDQeggLKARG-QPFE 145
                 ***************************************************6555444444.4454 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (156 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       437  (0.0243739); expected 358.6 (0.02)
Passed bias filter:                      384  (0.0214178); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.21s 00:00:00.62 Elapsed: 00:00:00.38
# Mc/sec: 1235.28
//
Query:       EEA20921.1  [L=513]
Description: oxysterol binding protein (Osh7), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.3e-91  304.8   0.1    7.4e-81  271.8   0.0    2.1  2  Oxysterol_BP  Oxysterol-binding protein


Domain annotation for each model (and alignments):
>> Oxysterol_BP  Oxysterol-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  271.8   0.0   4.2e-85   7.4e-81       1     272 [.      39     321 ..      39     328 .. 0.94
   2 !   30.5   0.9   9.1e-12   1.6e-07     315     360 ..     326     378 ..     323     389 .. 0.76

  Alignments for each domain:
  == domain 1  score: 271.8 bits;  conditional E-value: 4.2e-85
                   HHHCCHTTSTT-BCCCS---GGGEEEEEHHHHHHHCCTTCHHHHHHHC.SSHHHHHHHHHHHHHHCCCGCTSTSSSEEE---TT-EEEEEETT.... CS
  Oxysterol_BP   1 slwsilkkciGkDLskislPvffneplSlLqrlaedleyselLdkaakeddsleRlayVaaFalSsyastikrrlkKPFNPlLGEtfelvred.... 93 
                   +++s+l+  +G DLs+++lP+f++ep+S+L+r+++++ ++e+L  + + dd+leR++ V++F+lS+++ ++   +kKP+NP+LGEtf+++++     
    EEA20921.1  39 HIISQLR--PGADLSRVTLPTFILEPRSMLERITNFMAHPETLLPMPTIDDPLERFVSVVRFYLSGWHIKP-PGVKKPLNPILGETFTCYWDYndgt 132
                   589****..**************************************************************.799****************556786 PP

                   CEEEEEEEEEETTTTEEEEEEEE..CTEEEEEEEEEEEEE-SSEEEEEE-SEEEEEEEEE.....SEEEEEEE--EEEEE-TTTTS-EEEEEEEEEE CS
  Oxysterol_BP  94 kgfrfiaEQVsHhPpvsAfhaes..egweldgeikvkskflgkslevkpeGtahlellkk.....sgehYtwtkpttivhniivgklwvelsgevei 183
                   +g+ +i+EQ+sHhPp s++++++  +++++dg++k++skflg+s+   +eGta+l++l++     +ge+Y++t+p++++++i++gk+ +el++++ i
    EEA20921.1 133 RGY-YISEQTSHHPPKSSYFFMApeHHIRIDGTLKPRSKFLGNSAASLMEGTAVLTFLDRgknpaKGERYHLTQPNMYARGILFGKMKYELGDHSFI 228
                   777.******************9999*******************************43345566******************************** PP

                   EETTT--EEEEEEE---SSS---SSEEEEEEEE.TTS-EEEEEEEETTTEEEEEETTSTTS--EEEEETT-....BSXXGCGSSTTBCCCCCCH CS
  Oxysterol_BP 184 tnhstgdkakleFkkkglfsskksnkvegkvkd.kkkevlyeisGkwdeelyikkkktekkeeeedaseks....kvkekeeqeefeseklWka 272
                   +  ++   +++eFk+kg+f s+++n + g++k+ +++ev ye+sG w++e+y+k++ t+kk+   da++++     v++ e+q+e+es+klW  
    EEA20921.1 229 KCPENHFVCDVEFKTKGYF-SGTYNAIAGTIKNdQTGEVYYELSGLWNGEMYLKNNATGKKDLLFDATHAKhtppLVRSLEDQTERESQKLWYS 321
                   *888999************.59**********76999***********************99999999984456799***************76 PP

  == domain 2  score: 30.5 bits;  conditional E-value: 9.1e-12
                   HHTT-HHHHHHHHHHHHHHHHHHHHHH.CCTT----SSEEEEE......TTTT CS
  Oxysterol_BP 315 leegdideAeeeKkrlEekQRerrker.eekkewkpkwFekek......dpdt 360
                   l++++++ A++eK+++E++QRe++++r e++ ew+pk+F+++       ++ +
    EEA20921.1 326 LNARNHEVATAEKTKIEDQQREEAAKRaEGNVEWHPKLFRRVRggpggsEEGE 378
                   67899**********************655549*******9997666542233 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (513 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       612  (0.0341346); expected 358.6 (0.02)
Passed bias filter:                      477  (0.0266049); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.45
# Mc/sec: 3447.60
//
Query:       EEA20922.1  [L=393]
Description: oxysterol binding protein (Osh7), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.6e-91  307.0   0.1      4e-81  272.7   0.0    2.0  2  Oxysterol_BP  Oxysterol-binding protein


Domain annotation for each model (and alignments):
>> Oxysterol_BP  Oxysterol-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  272.7   0.0   2.2e-85     4e-81       1     272 [.      39     321 ..      39     325 .. 0.94
   2 !   31.9   0.8   3.4e-12   6.2e-08     315     369 ..     326     387 ..     322     391 .. 0.77

  Alignments for each domain:
  == domain 1  score: 272.7 bits;  conditional E-value: 2.2e-85
                   HHHCCHTTSTT-BCCCS---GGGEEEEEHHHHHHHCCTTCHHHHHHHC.SSHHHHHHHHHHHHHHCCCGCTSTSSSEEE---TT-EEEEEETT.... CS
  Oxysterol_BP   1 slwsilkkciGkDLskislPvffneplSlLqrlaedleyselLdkaakeddsleRlayVaaFalSsyastikrrlkKPFNPlLGEtfelvred.... 93 
                   +++s+l+  +G DLs+++lP+f++ep+S+L+r+++++ ++e+L  + + dd+leR++ V++F+lS+++ ++   +kKP+NP+LGEtf+++++     
    EEA20922.1  39 HIISQLR--PGADLSRVTLPTFILEPRSMLERITNFMAHPETLLPMPTIDDPLERFVSVVRFYLSGWHIKP-PGVKKPLNPILGETFTCYWDYndgt 132
                   589****..**************************************************************.799****************556786 PP

                   CEEEEEEEEEETTTTEEEEEEEE..CTEEEEEEEEEEEEE-SSEEEEEE-SEEEEEEEEE.....SEEEEEEE--EEEEE-TTTTS-EEEEEEEEEE CS
  Oxysterol_BP  94 kgfrfiaEQVsHhPpvsAfhaes..egweldgeikvkskflgkslevkpeGtahlellkk.....sgehYtwtkpttivhniivgklwvelsgevei 183
                   +g+ +i+EQ+sHhPp s++++++  +++++dg++k++skflg+s+   +eGta+l++l++     +ge+Y++t+p++++++i++gk+ +el++++ i
    EEA20922.1 133 RGY-YISEQTSHHPPKSSYFFMApeHHIRIDGTLKPRSKFLGNSAASLMEGTAVLTFLDRgknpaKGERYHLTQPNMYARGILFGKMKYELGDHSFI 228
                   777.******************9999*******************************43345566******************************** PP

                   EETTT--EEEEEEE---SSS---SSEEEEEEEE.TTS-EEEEEEEETTTEEEEEETTSTTS--EEEEETT-....BSXXGCGSSTTBCCCCCCH CS
  Oxysterol_BP 184 tnhstgdkakleFkkkglfsskksnkvegkvkd.kkkevlyeisGkwdeelyikkkktekkeeeedaseks....kvkekeeqeefeseklWka 272
                   +  ++   +++eFk+kg+f s+++n + g++k+ +++ev ye+sG w++e+y+k++ t+kk+   da++++     v++ e+q+e+es+klW  
    EEA20922.1 229 KCPENHFVCDVEFKTKGYF-SGTYNAIAGTIKNdQTGEVYYELSGLWNGEMYLKNNATGKKDLLFDATHAKhtppLVRSLEDQTERESQKLWYS 321
                   *888999************.59**********76999***********************99999999984456799***************75 PP

  == domain 2  score: 31.9 bits;  conditional E-value: 3.4e-12
                   HHTT-HHHHHHHHHHHHHHHHHHHHHH.CCTT----SSEEEEE......TTTTSSCEEEC-S CS
  Oxysterol_BP 315 leegdideAeeeKkrlEekQRerrker.eekkewkpkwFekek......dpdtgeevwkykg 369
                   l++++++ A++eK+++E++QRe++++r e++ ew+pk+F+++       ++ +++  w+++ 
    EEA20922.1 326 LNARNHEVATAEKTKIEDQQREEAAKRaEGNVEWHPKLFRRVRggpggsEEGEEDLDWIINA 387
                   67899**********************655549********997776543334444566665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (393 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       610  (0.0340231); expected 358.6 (0.02)
Passed bias filter:                      475  (0.0264934); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 2748.00
//
Query:       EEA20923.1  [L=499]
Description: histone deacetylase HosA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      3e-77  260.1   0.0    4.5e-77  259.6   0.0    1.3  1  Hist_deacetyl  Histone deacetylase domain
  ------ inclusion threshold ------
       0.15   12.2   0.0        0.9    9.8   0.0    2.0  2  CBP            Fungal calcium binding protein


Domain annotation for each model (and alignments):
>> Hist_deacetyl  Histone deacetylase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  259.6   0.0     5e-81   4.5e-77       1     307 []      61     360 ..      61     360 .. 0.92

  Alignments for each domain:
  == domain 1  score: 259.6 bits;  conditional E-value: 5e-81
                    SCCGTHHHHHHHHHHHHT.THHHHCCE.EE-----HHHHTTTS-HHHHHHHHCHHHHCHHT.TTHCCHHHCCTSTSSSSSTHCTTTCCHHHHHHHH CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Hist_deacetyl   1 hpenpkRlsaileslaesvglldelelliqpseatkeellkvHskeYlelleslsnelkkkeeakekeleeiasklldddtpvspktlkaallavg 96 
                    hp++p Rl  ++++l  ++g+  + ++l  +++at ee++++H+ +Yl++l+++     +      +++ +ias +  dd+p++++++++++l +g
     EEA20923.1  61 HPMKPWRLV-LTKELVLAYGMH-HAMDLYLSRAATFEEMAEFHTADYLDFLRQVIPADMEAA----EQSDRIASYNIGDDCPIFDGLFDYCSLYAG 150
                    899999999.888899989976.55667999*********************9876654444....23345666578999**************** PP

                    HHHHHHHHHHTTSSSEEEETT.SS--TT-BTTB-BTTBSS-HHHHHHHHHHHCC-SS-EEEEE-SSS--HHHHHHCTT-TTEEEEEEEE-.CCTST CS
                    xxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxx RF
  Hist_deacetyl  97 avleavdavlsgsvkaafvlv.rPpgHHakaseasGFClvNnvaiaikylqakhelkrvailDvDvHhGnGteeafysdpdvltlSiHry.egify 190
                    ++++a+++++++  +a+++++  ++ HHak++easGFC+vN+++++i +l +   ++rv+++D+DvHhG+G+e+af+s+++vlt+S+H+y +++f+
     EEA20923.1 151 GTVDAARKLINN--QADIAINwSGGLHHAKKTEASGFCYVNDIVLGILQLLR--FHPRVMYIDIDVHHGDGVEQAFWSTDRVLTVSFHKYdKDNFF 242
                    **********99..9***********************************99..346*********************************77**** PP

                    TSS--TT---....SGGGTTSEEEEEE-TT-BHHHHHHHHHHCHHHHHCCH--SEEEEEE-STTBTTSTT-S-BB-HHHHHHHHHHHCCCHGS-G. CS
                    xxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Hist_deacetyl 191 Pgtgaledlg....egkgkgfnlnvpleegtgdeeylkvfeeilrpvleefkPdlilvsaGfDalkgdplgelnlsvegykeltkklaeladkvkk 282
                    Pgtg le+ g     + g+++++nvpl++g++d+ yl++++ ++ +++e ++P +i++++G+D+l  d+lg +nl+v g++ ++ + ++l     +
     EEA20923.1 243 PGTGGLESNGpahpLNPGSKHAINVPLNDGIEDDAYLQLYKDVVSSCVETYQPGAIVLQCGADSLGCDRLGCFNLNVTGHGACVAYTKTLGL---P 335
                    *********96666667888***********************************************************************9...9 PP

                    EEEEE-S---HHHHHHHHHHHHHHH CS
                    xxxxxxxxxxxxxxxxxxxxxxxxx RF
  Hist_deacetyl 283 vvllleGGYnlealaravtavlsal 307
                    ++++++GGY++++++ra+++ +s+l
     EEA20923.1 336 MLVVGGGGYTPRNVSRAWAHETSIL 360
                    9*******************99876 PP

>> CBP  Fungal calcium binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0      0.18   1.6e+03       6      34 ..      81     109 ..      78     117 .. 0.81
   2 ?    9.8   0.0    0.0001       0.9       5      56 ..     286     337 ..     283     345 .. 0.85

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.18
         CBP   6 tsAldelkeavetftkakeaagCdwlaCl 34 
                  +A+d +   + tf+++ e    d+l  l
  EEA20923.1  81 HHAMDLYLSRAATFEEMAEFHTADYLDFL 109
                 699999999******99998887777655 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.0001
         CBP   5 vtsAldelkeavetftkakeaagCdwlaClsslaassAaCaAAlaElgLnil 56 
                 v+s ++ ++  + + +   +  gCd+l C +  ++   aC+A  + lgL +l
  EEA20923.1 286 VSSCVETYQPGAIVLQCGADSLGCDRLGCFNLNVTGHGACVAYTKTLGLPML 337
                 5666667777777777777888**********9****************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (499 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       586  (0.0326845); expected 358.6 (0.02)
Passed bias filter:                      516  (0.0287802); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.41
# Mc/sec: 3626.50
//
Query:       EEA20924.1  [L=309]
Description: allergen, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       590  (0.0329076); expected 358.6 (0.02)
Passed bias filter:                      353  (0.0196888); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 2037.94
//
Query:       EEA20925.1  [L=236]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0096   15.5   0.4      0.055   13.0   0.4    2.0  2  Saw1      Single strand annealing-weakened 1


Domain annotation for each model (and alignments):
>> Saw1  Single strand annealing-weakened 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0     0.025   4.5e+02       1      23 [.       1      23 [.       1      43 [. 0.84
   2 !   13.0   0.4   3.1e-06     0.055     187     232 ..     100     185 ..      55     193 .. 0.68

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.025
        Saw1  1 MaptiatvkisdklvLPlriFin 23
                Map   +++is+  vL  riF +
  EEA20925.1  1 MAPIRRYLRISKYSVLECRIFLE 23
                88888999*************86 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 3.1e-06
        Saw1 187 k...........qlneeandkpeileeaedd.............................kqeraseeeevkdekKpkikfkYkpv 232
                 +           + n+ +  ++eil e++d+                             +++ a e+++++d+kK+++++ Y+  
  EEA20925.1 100 QktfgnkqrmksNSNKLTGSTAEILVESDDEdvnertgitmsdipevadsedeeadsekrTEKAAVEATDNHDDKKLQLTTSYEGF 185
                 234444434333334444455566666666666666666666666666667777888887888999999**************865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (236 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       811  (0.045234); expected 358.6 (0.02)
Passed bias filter:                      451  (0.0251548); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 1697.10
//
Query:       EEA20926.1  [L=342]
Description: hypothetical protein PMAA_047380 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
       0.17   11.3   0.0       0.27   10.7   0.0    1.3  1  Hist_deacetyl  Histone deacetylase domain


Domain annotation for each model (and alignments):
>> Hist_deacetyl  Histone deacetylase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   1.5e-05      0.27     211     287 ..     233     317 ..     179     330 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 1.5e-05
                    EEE-TT-BHHHHHHHHHHCHHHHHCCH--SEEEEEE..-STTBTTS....TT-S-BB-HHHHHHHHHHHCCCHGS-.G..EEEEE CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxx.x.xxxxxx RF
  Hist_deacetyl 211 vpleegtgdeeylkvfeeilrpvleefkPdlilvsa..GfDalkgd....plgelnlsvegykeltkklaeladkv.k.kvvlll 287
                    +  e+ ++++e +++++ +++ +lee +Pd +++ +  GfD ++ d    + +++ +    +++l+k+l++l++ +   k++++ 
     EEA20926.1 233 IREEKPEKEQEKTNLLSDLFIGMLEEAQPDQVIYILidGFDLVEMDepeaNKSDFWWLLTCFYSLIKDLRKLKKPHpViKLLITY 317
                    556677889999*****************988765444********99888889999999*************998655666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       607  (0.0338558); expected 358.6 (0.02)
Passed bias filter:                      435  (0.0242624); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2459.58
//
Query:       EEA20927.1  [L=422]
Description: amidohydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.4e-21   77.2   0.0    2.1e-21   76.6   0.0    1.3  1  Peptidase_M20  Peptidase family M20/M25/M40
    4.4e-14   52.3   0.0    1.2e-13   50.9   0.0    1.7  1  M20_dimer      Peptidase dimerisation domain


Domain annotation for each model (and alignments):
>> Peptidase_M20  Peptidase family M20/M25/M40
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.6   0.0   2.4e-25   2.1e-21       1     177 [.      79     371 ..      79     392 .. 0.88

  Alignments for each domain:
  == domain 1  score: 76.6 bits;  conditional E-value: 2.4e-25
                    EEEEES-BSS.TTCGGGSSSTTSEE....ETTT....EEESTTTTTTHHHHHHHHHHHHHHHHHTTT-SSEEEEEEESTTSSTTTHHHHHHH.HHH CS
                    xxxxxxxxxx.xxxxxxxxxxxxxx....xxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxx RF
  Peptidase_M20   1 llgsHlDvVp.eeetdgwttpfslt....eedG....klyGrGaddmkggvlaalealralkdegikpkgtivllfqpdEEggrgGakalle.gle 86 
                    ll++++D++p +e t g   p+++     + +G    +++++G+d + + +laa+e+l++ + ++    gt+ +lfqpdEE g gGa+a+++ gl 
     EEA20927.1  79 LLRADMDALPvKELT-GL--PYASSitmsDAEGvekpVMHACGHDMHITCLLAAAELLANTQHAW---SGTLIVLFQPDEERG-GGAQAMVDdGLY 167
                    79********44444.55..***999999666677779**********************99999...*************76.*********999 PP

                    .TTTCESEEEEEEEESSSBTCHSTETEEEE.................................................................. CS
                    .xxxxxxxxxxxxxxxxxxxxxxxxxxxxx.................................................................. RF
  Peptidase_M20  87 .erekvdavfelhieepgileagklaigvv.................................................................. 115
                     +   +d+ f+ h++    + ag+++ +++                                                                  
     EEA20927.1 168 sKIPVPDYCFGQHVM---RMRAGTIGSRPGtimaaadsmkvtvfgrgghgslphqtvdpallaahivvrlqsivsreidptdlgvvtvgslqagqt 260
                    9999***********...66669999999999**************************************************************** PP

                    .............................................E.EEEEEEEEESHEEECCHHHHHHHHHHHHHHHTSC.EEEE.EESSSBHTH CS
                    .............................................x.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxx.xxxxxxxxx RF
  Peptidase_M20 116 .............................................k.vevelleggapvtlndsplvkalaeaaeelfgek.veli.vsgpggtda 163
                                                                   ++     +  p+t nd +++ +la++ e  fg +   +i  s   ++d+
     EEA20927.1 261 eniiadraeigldfrtvkletrekilsairriveaecmasgspkpPiFT---PTRRFPPTNNDRDVASKLAASFETHFGDSfDGDIsRSN-VAEDF 352
                    *******************************999999998887532133...36788999999*************99988533333666.***** PP

                    HHH...TTTEEEEE.EE.S CS
                    xxx...xxxxxxxx.xx.x RF
  Peptidase_M20 164 rff...agiptvmi.fg.p 177
                    + +   +g+p++++ +g  
     EEA20927.1 353 STLatsKGVPSCFWfLGgI 371
                    ***9999999664527734 PP

>> M20_dimer  Peptidase dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.9   0.0   1.4e-17   1.2e-13       8     105 ..     202     297 ..     199     300 .. 0.95

  Alignments for each domain:
  == domain 1  score: 50.9 bits;  conditional E-value: 1.4e-17
                 EEEEEEE-B-EEGG-TTTTB-HHHHHHHHHHCSCTTEEC.....TCCTCCCCCEECCE-CCCCEESSEEEEEEEEEHHHHHHHHHHHHHHHHHHTSCC CS
   M20_dimer   8 ggkitvkgkagHsgapgagaNAieklarllaeledeegdiaeerslprttlnvtgiegGsaknvipdeaeakidiRllpgedpeevleeieeilekea 105
                 ++k+tv g++gH++ p+  +++  ++a+++ +l++  +++    ++    ++v+++++G+  n+i+d+ae  +d+R+++ e++e++l +i+ i+e+e+
  EEA20927.1 202 SMKVTVFGRGGHGSLPHQTVDPALLAAHIVVRLQSIVSREI--DPTDLGVVTVGSLQAGQTENIIADRAEIGLDFRTVKLETREKILSAIRRIVEAEC 297
                 79**********************************99977..88888889*******************************************9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (422 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       456  (0.0254337); expected 358.6 (0.02)
Passed bias filter:                      442  (0.0246528); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2963.69
//
Query:       EEA20928.1  [L=151]
Description: norsolorinic acid reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.3e-15   54.9   0.0    8.4e-15   54.7   0.0    1.1  1  Aldo_ket_red  Aldo/keto reductase family


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.7   0.0   4.7e-19   8.4e-15     179     293 ..       2     106 ..       1     107 [. 0.92

  Alignments for each domain:
  == domain 1  score: 54.7 bits;  conditional E-value: 4.7e-19
                   HHHTT-EEEEBSTTGGGTTGTTTSS---SSSCCC-------TS-HHHHHHHHHHHHHHHHTT-.-HHHHHHHHHTTSTT-SEEEE--SSHHHHHHHH CS
  Aldo_ket_red 179 ckkkgvpliaysplggGlltgkyqseedkedkeprkdlkrdertsknldaaeelselakehgv.slaqlalryalsqpavgivipgasnieqlednl 274
                   + + g++l ++ +lggG +++  q e+  ++ +  ++               +l++++  hg+ s++q+al+y++++ +++++++g + +e+l+dn+
    EEA20928.1   2 ALHFGMALCPWDVLGGGQFKTARQLEAAENSNQGSRS-----------GVSAALERVVSGHGInSVQQIALAYIMQKARNVFPVVGGRMVEHLHDNI 87 
                   4556999*****************9999887666665...........789999999999************************************* PP

                   GGGG----HHHHHHHHHHH CS
  Aldo_ket_red 275 dalelklseeevaeldell 293
                   +al++ l++e++++ld++ 
    EEA20928.1  88 GALSIYLTDEQIRYLDSIK 106
                   ****************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (151 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       347  (0.0193541); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.25s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1123.27
//
Query:       EEA20929.1  [L=174]
Description: norsolorinic acid reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.2e-19   68.8   0.0    4.7e-19   68.7   0.0    1.2  1  Aldo_ket_red  Aldo/keto reductase family


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.7   0.0   2.6e-23   4.7e-19      79     158 ..      81     163 ..      40     170 .. 0.89

  Alignments for each domain:
  == domain 1  score: 68.7 bits;  conditional E-value: 2.6e-23
                   SSS-HHHHHHHHHHHHHHHT-S-EEEEEE-S--TTS-.HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHH....HHTTT--EE CS
  Aldo_ket_red  79 sglskeniresleeslkrLgtdyvDllllHrpdpslpsieevldaleelvkeGkiraiGvSnfsveqleka....kkkkkvkiv 158
                   +   k+++r s+ +sl++L+t y+Dll++H++d +++ iee++d l+ lv++Gk+ ++G+S ++++ +  a    k ++k++++
    EEA20929.1  81 EETIKKSLRLSIADSLRKLQTTYIDLLYVHWWDWTTS-IEELMDSLHNLVQQGKVLYLGISDTPAWVVATAntyaKDHGKTPFS 163
                   3444568888999************************.******************************9999999999999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (174 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       352  (0.019633); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.24s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1301.06
//
Query:       EEA20930.1  [L=505]
Description: benzoate 4-monooxygenase cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.9e-64  216.8   0.0    6.4e-64  216.4   0.0    1.0  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  216.4   0.0   3.6e-68   6.4e-64      20     453 ..      58     486 ..      39     492 .. 0.90

  Alignments for each domain:
  == domain 1  score: 216.4 bits;  conditional E-value: 3.6e-68
                 CCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGH.HHHHHHHHHHHHHHTSHSTT.THHH CS
        p450  20 eelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfang.ekwkklRrfltptltsfgkl.slee 116
                 ++   +l++l+k ygpi r+ +   ++v + +p++++ v ++k+    ++ +++++a    +f  +  l+ +g ++ ++ Rr  +  ++s ++   l++
  EEA20930.1  58 GQYAFKLKELHKIYGPIIRISP---ETVHIDDPDYFEVVHNQKN---GREVKPPHVAE---TFGPYPALLGTGpHELHRVRRSALSPFFSRKAVlDLVP 147
                 55566799***********976...6788999***********7...77788999998...9***********9888888888888888884555**** PP

                 HHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCCCHHHTCCSCHHHHHHHHHHHH CS
        p450 117 lveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelssllskssvqllllfpllkylptkllrklkeavkk 215
                 ++++ +++l+++l++ + + ++++++ +++ ++ld+i++ +F ++  +  ++++ + ++ + +++  +s  ++ +  l++l   lp++  +++  av k
  EEA20930.1 148 TIQRPTAILCRRLQEASLTGETMNLKYIFAAVTLDIINDYCFAREPTTTLEPDFGKKETDNVAYFLKVSLLNTHIPWLMRLTYSLPDRVSKTFTPAVAK 246
                 ***********************************************9*****9999999999988887888888888888889*************** PP

                 HHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHC...TTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHC.CTT CS
        p450 216 lkdlldklieerretldsakksrrdfldalllak...kekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklreEidevl.gdk 310
                 + d+ ++l ++ ++  + ++ s+ + ++ ++  +   ++    ++l+ + l+ +++ l +aG+dTt+++l+ + y++  nP++  +l +E+++++   +
  EEA20930.1 247 ILDFRMELSRQVEAIRNGQDTSHQTAAHRTVFHElldSTLPP-DELKPARLRDEAFSLVAAGSDTTAHVLRGTTYHISANPTIRLQLFNELKTAIpDPD 344
                 **************9999955566666666665553224555.59**************************************************6666 PP

                 TT-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS.CEEETTEEE-TT-EEEEEHHHHHT-TTTSSSTTS--GGGGB-TTSCTESSCTT--TTEEG CS
        p450 311 reptyddlqklpyldavikEtLRlhpvvplllpRevtk.dvvirgylipkGtevivnlyalhrdpevfpnPeeFdpeRFldekgnskrksfaflPFGaG 408
                   p+  +l+klpyl avi+E LRl ++v  ++ R+ +      +gylip +t+v +++  +h +++ fp+P++F+peR+l  ++   r + + + F+ G
  EEA20930.1 345 NLPSLPELEKLPYLSAVIHEGLRLANPVTHRIIRQYPDkAFDYQGYLIPPNTIVGMSPNLVHFNEDKFPEPQVFKPERWLGPDN--ARLQRYLISFSRG 441
                 69***************************9*99999876899***************************************987..49*********** PP

                 GGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGEEESSCSSE CS
        p450 409 pRnCiGerlArmelklflatlLqnFevelqpetdpppileksgll 453
                 pR+C+G  lAr el+++la+++++Fe+++ + ++ ++i+   +++
  EEA20930.1 442 PRACLGIALARAELFIILASVFRQFELDVSEIERSRDIDFSRDFI 486
                 *****************************9999999988776555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (505 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       368  (0.0205254); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.41
# Mc/sec: 3733.17
//
Query:       EEA20931.1  [L=272]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.6e-18   67.3   0.1    2.1e-18   66.8   0.1    1.2  1  NAD_binding_10  NAD(P)H-binding
     0.0036   16.8   0.0     0.0056   16.2   0.0    1.4  1  Epimerase       NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.8   0.1   2.4e-22   2.1e-18       1     181 [.       8     225 ..       8     228 .. 0.74

  Alignments for each domain:
  == domain 1  score: 66.8 bits;  conditional E-value: 2.4e-22
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHH.....CTTTCEEEE--TT-CCHHHHHHT.....T-SEEEES---TCC.........HHH CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpeklaele.....aeeglevvegdvtdvedlaealk.....gadaVvsalggggk.........dee 76 
                     G++Gk++ +l+  llar+ ++vt ++Rn+e+  e+      +  +++v+  ++ dv++ a+a +       d Vv+a+g+ggk         d++
      EEA20931.1   8 GGHGKIALYLTPLLLARS-WNVTSVIRNAEHEVEILalgngKPGKVSVLLSSLDDVKSQADAQAvldkvKPDYVVWAAGAGGKgapqrtyaiDQD 101
                     9****************6.*********9987655435454567889988877776555544444444445799999988888788777777777 PP

                     HHHHHHHH.HHHCT--EEEEEEETTTTSGCGCHHHH........HHHHCCHHHHHHHHHHHHHHHH...........SSSEEEEEEE-CEE-ST- CS
  NAD_binding_10  77 gaknivda.akeagvkRfvlvsaigvgdevpgefge........wnkellkaylaakraaeellra...........sgldwTivrpggLtdept 151
                     +ak  ++    +  v +f+l+s +g+++  p+ ++e        +++  l +y +ak +a+++  a           ++++   +rpg+L d+p+
      EEA20931.1 102 AAKYFIASsFAAPSVTKFLLISHMGSRKVKPSWLSEdgwkrtqwLWSVGLPDYCKAKWEADQYQTAlaaitkqreptRKFQSISLRPGHLIDDPA 196
                     78887765156778*************8766654332211111144457899***********655555778888988****************7 PP

                     -SEEEEETTSS----EEEHHHHHHHHHHHC CS
  NAD_binding_10 152 tkyrvvekgepfkggsisradVAdvlvavl 181
                     t+ ++  ++    +gs++r+dVA v+ ++l
      EEA20931.1 197 TGKVA-LGHVAAAEGSVTREDVAIVADRLL 225
                     76444.455667789********8876665 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   6.3e-07    0.0056       1      79 [.       4      91 ..       4     130 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 6.3e-07
                EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC.............EEEE-.-TT-HHHHHHHHHHHT-SEEEE--S---HHH CS
   Epimerase  1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl.............elvel.dltdrsalerlfkeeqpdavihlAavggvaa 79
                +l++G++G i  +l+  ll++ ++v+ + r+  a+++ +   +              l  l d++ +++ ++++++++pd+v+ +A+ gg +a
  EEA20931.1  4 VLLLGGHGKIALYLTPLLLARSWNVTSVIRN--AEHEVE---IlalgngkpgkvsvLLSSLdDVKSQADAQAVLDKVKPDYVVWAAGAGGKGA 91
                6899**********************99999..333333...23458899**99873333326788889****************99888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (272 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       357  (0.0199119); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 1843.93
//
Query:       EEA20932.1  [L=1188]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1188 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       838  (0.0467399); expected 358.6 (0.02)
Passed bias filter:                      361  (0.020135); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.83u 0.29s 00:00:01.11 Elapsed: 00:00:00.50
# Mc/sec: 7191.65
//
Query:       EEA20933.1  [L=534]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.019   14.0   1.1      0.037   13.1   1.1    1.4  1  Corona_nucleoca  Coronavirus nucleocapsid protein
       0.66    9.6   8.1        1.5    8.3   8.1    1.5  1  SR-25            Nuclear RNA-splicing-associated protein


Domain annotation for each model (and alignments):
>> Corona_nucleoca  Coronavirus nucleocapsid protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   1.1   4.2e-06     0.037     148     216 ..     279     341 ..     271     350 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 4.2e-06
                      ----TT---STTEEETT-SXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Corona_nucleoca 148 lrladGtvlPqgfyvegsgrsraasrsgsrsrsrsrnrarsssrgrspastakndveeeiaalvLekLg 216
                      l++    + P+ + +  +g s+ +s s+s+ +s+s n++  +++g+++ +t++ + + +i++  ++ L+
       EEA20933.1 279 LQF---GLYPEDYLLAYEGNSNGSSSSSSNNNSNS-NSNSNKTKGKKNRRTKRMGKASKIIV--FNNLN 341
                      555...45688888888999**********99999.88888999999999998888888765..66666 PP

>> SR-25  Nuclear RNA-splicing-associated protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   8.1   0.00017       1.5      67     103 ..     296     330 ..     291     341 .. 0.43

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00017
       SR-25  67 ssssssssssssssssssssddrkkrgkkkdkkkkkk 103
                 s+ ssssss+  s   s+s++++ k +k++++k+  k
  EEA20933.1 296 SNGSSSSSSNNNS--NSNSNSNKTKGKKNRRTKRMGK 330
                 2223333222222..2333333333333333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (534 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1061  (0.0591779); expected 358.6 (0.02)
Passed bias filter:                      715  (0.0398795); expected 358.6 (0.02)
Passed Vit filter:                        79  (0.00440627); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.66u 0.29s 00:00:00.95 Elapsed: 00:00:00.45
# Mc/sec: 3569.65
//
Query:       EEA20934.1  [L=339]
Description: inositol oxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.7e-123  410.4   0.3   4.8e-123  409.6   0.3    1.4  1  MIOX      Myo-inositol oxygenase
  ------ inclusion threshold ------
      0.024   14.8   0.0        1.1    9.5   0.0    2.4  2  HD        HD domain
      0.025   14.6   0.9       0.79    9.7   0.1    2.6  2  NOG1_N    NOG1 N-terminal helical domain
       0.06   13.6   0.0       0.11   12.7   0.0    1.5  1  UBD       Ubiquitin-binding domain


Domain annotation for each model (and alignments):
>> MIOX  Myo-inositol oxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  409.6   0.3  1.1e-126  4.8e-123       1     249 []      91     339 .]      91     339 .] 0.99

  Alignments for each domain:
  == domain 1  score: 409.6 bits;  conditional E-value: 1.1e-126
        MIOX   1 kdrvkefykeqhtkqtvdfvkkkrkefkkkkrakmtiwealellnelvdesdPdvdlsqiehllqtaeairkdypdkdWlqltglihdlGkvlllfkae 99 
                 ++rvk+fy eqhtkqtv+++ ++r++f++++ra+m++w+a+e+ln+l+d+sdPd++lsqiehllqtaeair+d ++++W+qltglihdlGk+l++f+a+
  EEA20934.1  91 CERVKSFYLEQHTKQTVAYNLQARNKFHSTTRARMSVWQAIEMLNTLIDDSDPDTSLSQIEHLLQTAEAIRRD-GKPRWMQLTGLIHDLGKLLYFFDAR 188
                 589**********************************************************************.************************* PP

        MIOX 100 pqWavvGdtfpvGckfsesivy.kesfkenpdlkdekyntklGiykencGldnvllswghdeylykvlkenkstlpeealamiryhsfypwhkegaykh 197
                 +qW+vvGdtfpvGc+f+e+i+y +esf+ npd  +e+++  lGiy +++Gldnv++swghdeyly+v+k ++stlp+ealamiryhsfypwhkegay++
  EEA20934.1 189 GQWDVVGDTFPVGCAFDERIIYgRESFRLNPDCGHEVFDNGLGIYFPGIGLDNVMISWGHDEYLYHVVK-DQSTLPDEALAMIRYHSFYPWHKEGAYQE 286
                 *********************************************************************.99*************************** PP

        MIOX 198 lmnekdeellkavkafnkydlyskseekpdveelkPyyqelidkylpe.klkw 249
                 lmnekd+++l+av+afn+ydlysks+  p+v+el+Pyy+elid+++pe +++w
  EEA20934.1 287 LMNEKDKKMLRAVQAFNPYDLYSKSDGLPKVDELRPYYEELIDEFFPEkVINW 339
                 ***********************************************956666 PP

>> HD  HD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.0   0.00024       1.1       5      41 ..     153     182 ..     146     198 .. 0.75
   2 ?    2.9   0.0     0.027   1.2e+02      57      95 ..     246     280 ..     220     319 .. 0.74

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00024
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTHHH CS
          HD   5 sleVaklarrlaedlgeeedrellllaaLlHDiGkgp 41 
                  l++a+ +rr       + ++ + +l +L+HD+Gk +
  EEA20934.1 153 LLQTAEAIRR-------DGKPRWMQLTGLIHDLGKLL 182
                 4444444433.......456888************87 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.027
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCCHHHHH CS
          HD  57 laHekvgaeilrevekrlgldledvaklirehheswegk 95 
                  +H ++ + ++++   ++    ++++++ir+h++    k
  EEA20934.1 246 WGHDEYLYHVVKDQSTLP----DEALAMIRYHSFYPWHK 280
                 479999999999999999....569*******9876544 PP

>> NOG1_N  NOG1 N-terminal helical domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.1     0.027   1.2e+02      76     107 ..     132     163 ..      76     165 .. 0.84
   2 ?    9.7   0.1   0.00018      0.79      44      79 ..     294     329 ..     279     333 .. 0.71

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.027
      NOG1_N  76 elldvlvdkdelkksLaqvkwarklirkigke 107
                 e+l++l+d++    sL+q++ + ++++ i+++
  EEA20934.1 132 EMLNTLIDDSDPDTSLSQIEHLLQTAEAIRRD 163
                 78999999999999******999999999875 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.00018
      NOG1_N  44 rkvrtasntlsdkLeeivkkfPnldelhpFyrelld 79 
                 +++r+++      L++  +  P++del p+y+el+d
  EEA20934.1 294 KMLRAVQAFNPYDLYSKSDGLPKVDELRPYYEELID 329
                 334444443345677778899*************98 PP

>> UBD  Ubiquitin-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   2.5e-05      0.11      20      73 ..     108     163 ..      90     195 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.5e-05
         UBD  20 raqlerereeFfdTrvtgrkeiWdalkaalevleedd....lataqaildaaeitlpt 73 
                 + +l + r++F +T + +r  +W+a++++ ++++++d    l++ +++l++ae +  +
  EEA20934.1 108 AYNL-QARNKFHST-TRARMSVWQAIEMLNTLIDDSDpdtsLSQIEHLLQTAEAIRRD 163
                 3333.678999988.578************9998888776677777888888876555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (339 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1121  (0.0625244); expected 358.6 (0.02)
Passed bias filter:                      594  (0.0331307); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.42
# Mc/sec: 2438.58
//
Query:       EEA20935.1  [L=313]
Description: glycerol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.3e-44  151.7   0.1    3.3e-42  144.7   0.1    2.0  1  Aldo_ket_red  Aldo/keto reductase family


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  144.7   0.1   1.8e-46   3.3e-42       2     293 ..      20     286 ..      19     287 .. 0.94

  Alignments for each domain:
  == domain 1  score: 144.7 bits;  conditional E-value: 1.8e-46
                   EEEE-SSS-ST.TS-HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH....-TTTGGG-EEEEEE--SSSTTSSSS-HHHHHHHHHHHH CS
  Aldo_ket_red   2 lglGtwqlgskeeiskeealellrraleaGinffDtAevYgkgqseellGealkk....srkkreeviiatKvdlrdaeiksglskeniresleesl 94 
                   lg+Gtwq       ++ee ++++ +a++aG++++DtA vY    +e  +G+ +k+      +kre+++++tK+        ++  +++++e l++sl
    EEA20935.1  20 LGFGTWQS------TPEETQRAVYHAIKAGYRHIDTALVY---GNEVDVGKGIKAaiddGLVKREDLFVTTKL--------WNVYANRVEEGLDASL 99 
                   89****55......589***********************...788889998888887799************........7777899********* PP

                   HHHT-S-EEEEEE-S--TTS-......................HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHHHHTTT--EEEEE-B-BTT-HH CS
  Aldo_ket_red  95 krLgtdyvDllllHrpdpslp.....................sieevldaleelvkeGkiraiGvSnfsveqlekakkkkkvkivavqveynllrel 170
                   k Lg++yvDl+l+H+p ++ +                     +  ++++ +e+l   Gk +a+GvSn+sv  lek+++++ + ++++q+e +++  l
    EEA20935.1 100 KALGLEYVDLYLVHWPVRMNDkgnhplfpkhpdgsrdiifshNHVDTWKDMEKLPATGKTKAVGVSNYSVPYLEKLLAEATIVPATNQIENHPQ--L 194
                   **********************************************************************************************..* PP

                   HHTTHHHHHHHTT-EEEEBSTTGGGTTGTTTSS---SSSCCC-------TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTSTT-SEEEE--SSH CS
  Aldo_ket_red 171 eeegllelckkkgvpliaysplggGlltgkyqseedkedkeprkdlkrdertsknldaaeelselakehgvslaqlalryalsqpavgivipgasni 267
                   ++++++++ck kg+ + aysplg+                               l  ae + e+a++++vs+a++ l++ l   ++++v+ ++ n+
    EEA20935.1 195 AQQEIVDFCKTKGIVIEAYSPLGSTGSP---------------------------LFNAEPVVEIANKRNVSPATVLLSWHL--ARGSVVLAKSINP 262
                   ***********************53322...........................2357899********************..9************ PP

                   HHHHHHHGGGG----HHHHHHHHHHH CS
  Aldo_ket_red 268 eqlednldalelklseeevaeldell 293
                   +++++n +    +l++e+va l++++
    EEA20935.1 263 DRITANRELI--DLDAEDVALLQKYA 286
                   **********..********999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (313 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       470  (0.0262145); expected 358.6 (0.02)
Passed bias filter:                      459  (0.025601); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 2062.84
//
Query:       EEA20936.1  [L=540]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (540 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       476  (0.0265492); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.49
# Mc/sec: 3285.23
//
Query:       EEA20937.1  [L=2382]
Description: TOR pathway phosphatidylinositol 3-kinase TorA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.5e-132  442.0   0.3   1.5e-132  442.0   0.3    2.2  2  FAT             FAT domain
      1e-68  231.9   0.8    1.9e-68  231.0   0.1    1.9  1  PI3_PI4_kinase  Phosphatidylinositol 3- and 4-kinase
    9.2e-65  217.5   8.2    9.7e-61  204.4   0.4    4.7  4  DUF3385         Domain of unknown function (DUF3385)
    1.3e-40  137.8   0.2    1.3e-40  137.8   0.2    4.4  3  FRB_dom         FKBP12-rapamycin binding domain
    3.9e-17   62.4  13.1    0.00018   21.8   0.0    9.5  8  HEAT_2          HEAT repeats
      1e-16   61.0  13.4     0.0004   20.8   0.0   11.7 11  HEAT_EZ         HEAT-like repeat
    3.2e-15   54.9  21.8     0.0047   17.1   0.0   12.7 11  HEAT            HEAT repeat
    2.4e-13   49.6   3.5    2.7e-13   49.5   1.0    2.3  2  FATC            FATC domain
    0.00031   20.6   5.1        2.1    8.3   0.0    7.1  7  UME             UME (NUC010) domain
     0.0011   18.9   0.2      0.087   12.7   0.0    4.1  2  Sec7_N          Guanine nucleotide exchange factor in Golgi t
     0.0023   17.5   1.8        2.2    7.8   0.0    4.9  5  CLASP_N         CLASP N terminal
     0.0056   17.3   5.3    4.4e+02    1.6   0.0    8.0  7  Vac14_Fab1_bd   Vacuolar 14 Fab1-binding region
  ------ inclusion threshold ------
      0.021   13.9  10.5      0.086   11.9   0.1    4.5  3  MMS19_C         RNAPII transcription regulator C-terminal
       0.06   13.4   1.7         26    5.1   0.1    4.2  3  TPR_7           Tetratricopeptide repeat
       0.11   12.7   0.2        5.2    7.2   0.0    4.0  2  Spore_III_AB    Stage III sporulation protein AB (spore_III_A
       0.16   12.5   8.4         12    6.5   0.0    6.0  5  TPR_19          Tetratricopeptide repeat
       0.17   12.1   4.4         44    4.5   0.2    4.2  3  TPR_2           Tetratricopeptide repeat
       0.17   11.6   3.2        3.1    7.5   0.0    3.9  3  TPR_11          TPR repeat
       0.23   11.7   1.1         37    4.6   0.0    4.8  5  RTP1_C1         Required for nuclear transport of RNA pol II 
       0.62   10.3   3.0    1.1e+02    3.2   0.1    4.3  4  ANAPC3          Anaphase-promoting complex, cyclosome, subuni
        1.4    8.8   4.5         46    4.1   0.2    3.7  3  TPR_1           Tetratricopeptide repeat
        1.6    9.5   0.0        1.6    9.5   0.0    4.3  3  TPR_16          Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> FAT  FAT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.4       1.8   1.5e+03     223     283 ..    1277    1329 ..    1251    1333 .. 0.67
   2 !  442.0   0.3  1.9e-135  1.5e-132       1     346 []    1371    1739 ..    1371    1739 .. 0.97

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 1.8
                  SS-SS---............HH.HHCCCTCCCCCCCCCCCT.S...-SSCCHHHHCCHHCTC CS
         FAT  223 elqsgleaqkeptnleeftkll.arcylkkGewqealqkldwseekieeilqsysaateidp 283 
                  +++++l+  ++   +  ++k +  r   +k  w e+lq+        ee+l++y++  + dp
  EEA20937.1 1277 TINNQLQ--QSDAAIGILRKAQaYRDVELKETWFEKLQR-------WEEALAAYKRREKQDP 1329
                  3333333..457777888888877888899999999999.......7888888887766665 PP

  == domain 2  score: 442.0 bits;  conditional E-value: 1.9e-135
                  CCCTTCCCCTSSSGHHCCCCT....TSSSS--CCCHCCCCHH--CCHCHHCCCHCCCCCCCCCTS---SCCCCCHHHHHCCCCCHHHCHHCCHHCSS CS
         FAT    1 aplaaeaaWrlgqWdsmeeylsvlkkdspdkaffeailalhrnqfdeakeliekarqlldtelsalvgesynraygvlvrvQmlaEleeiiqykqkl 97  
                  aplaa+aaW+ gqWd+m++yl v+k+++pd++ff+aila+ rnqf+ea+ +iek+r++ldtelsal gesynray+v+vrvQmlaEleeii +kq+ 
  EEA20937.1 1371 APLAAAAAWGRGQWDLMDSYLGVMKEHTPDRSFFGAILAINRNQFEEAAHYIEKVRNGLDTELSALLGESYNRAYDVVVRVQMLAELEEIIVFKQNV 1467
                  79*********************************************************************************************** PP

                  ----TTTTTTT----TTS-TTTGCCCTTTCCCCTCCCHCCCHCHCCS-STTCCCCCCCCHCHHHHCCSTTHHCCCCCHCTT.......TT.TSSCCC CS
         FAT   98 ssseklksllktWrkRlpgcqdnvevwqdiltvRslvlspiedllkgvkaemwlkfanlarksgrlslAekaLkelleedp..eewlprappevvya 192 
                  +++ek++++++tW+kRl+gcq+n evwq++l+vR+lv+ p+e+      ++m +k+anl+rks+r+++Ae++L +l++e +  +  ++  ppev ya
  EEA20937.1 1468 GDPEKQQAMRETWNKRLLGCQQNAEVWQRMLKVRQLVIPPHEN------MDMLIKYANLCRKSNRMGIAERTLASLETEISgpNGIETVVPPEVKYA 1558
                  *******************************************......***************************999998766666889****** PP

                  HHHHHHHCCHHHHHSSCCHHHHCCTSSCCCSS-SS---...................................HHHHCCCTCCCCCCCCCCCT.S.. CS
         FAT  193 ylKylwssgeqkealqkLreftsellekkeelqsgleaq.......................keptnleeftkllarcylkkGewqealqkldwsee 266 
                  ++K+ w++g+q +alq+L+efts l+++ ++++  l+ +                       +    + +++klla+ ylk+Gewq+alq++dw+ +
  EEA20937.1 1559 RFKFAWAQGHQVDALQSLKEFTSALADDLTRYNALLANHtdhdgtngvngmldnnpdvnhlrSRIGDVTKLKKLLAKSYLKQGEWQTALQSGDWRPQ 1655
                  *****************************9666666666667888888999999999999999********************************** PP

                  .-SSCCHHHHCCHHCTCCCHSTTCCCCHHHHHCCHHHHHHSSSS....S-TCC.HHHHCCT..CCHHHHTTTSSTTTCHHHHHC CS
         FAT  267 kieeilqsysaateidpswykawhtwalfnfevvskeeeqkeeee...pedlq.eyvvpavkgflksislssenslqdtlRLLt 346 
                  +++e+l++ysaat++++++ykawh+wal+nfevv+++  q+++++   p +++ e+v pa++gf++sislss++slqdtlRLLt
  EEA20937.1 1656 HVREVLNAYSAATQYNRDSYKAWHSWALANFEVVTTLAAQQSRDGssvPGHIInEHVLPAIRGFFRSISLSSTSSLQDTLRLLT 1739
                  ****************************************999999999**********************************8 PP

>> PI3_PI4_kinase  Phosphatidylinositol 3- and 4-kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  231.0   0.1   2.3e-71   1.9e-68       3     249 ..    2014    2261 ..    2012    2262 .. 0.98

  Alignments for each domain:
  == domain 1  score: 231.0 bits;  conditional E-value: 2.3e-71
                      EEEEECSSCHHHHHHHHHHHHHHHHHHHHTTTTCCCT-------EEESSSSEEEEE--TTEEEHHHHHHHHHHHCTTSTCHHHHH.HHHHCHC CS
  PI3_PI4_kinase    3 agiykvgddlrqdelivqvfklmdeelskennpkrrklalktysviplgrkcgiielvassetaaslldeklekkgvpptasves.lrvaldk 94  
                       +++k+++d rqde+++q+f+l++++l ++++  +r+l+++++ +ipl++++g+i++v +s+t++ l++e++e +++  ++++++ l++a+d+
      EEA20937.1 2014 MYALKGHEDIRQDERVMQLFGLVNTLLDNDSESFKRHLSVQQFPAIPLSQNSGLIGWVSNSDTLHALIKEYRESRRILLNIEHRImLQMAPDY 2106
                      5789***********************************************************************99999999999999**** PP

                      HCCHHHHHCC.HHHHHHTSSTTHHHHHHHHHSSSHHHHHHHHHHHHHHHHHHHHHHHHHT-TT--TTTEEEETTTSEEEESSTTTCCTCSHCS CS
  PI3_PI4_kinase   95 kklkkekklk.fekrtalkpksgllqeFvkkspsaeewlearkqFvrslaklsvldyilgngDRhldNilvdktsgklihIDfGlilpdewkl 186 
                      ++l +++k++ f   + +++ ++l++ ++ ks+s e wle+r++++rsl + s+++yilg+gDRh++N+l+d+ +g+++h+DfG++++ ++++
      EEA20937.1 2107 DNLSLMQKVEvFGYAMDNTTGKDLYRVLWLKSKSSESWLERRTNYTRSLGVTSMVGYILGLGDRHPSNLLLDRLTGTVVHVDFGDCFEIAMHR 2199
                      **********9999******************************************************************************* PP

                      SSS-.SSSSSS-THHHHHHTSTTCCHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHCCSSC CS
  PI3_PI4_kinase  187 lpfpqekvPfrltrelvlaidpskdeglfresceealealrrdqnlltrllkkavkdglilwe 249 
                       ++p e+vPfrltr+l +a++ s  eg +r +ce +++++r++++ l+++l+++++d+li+w+
      EEA20937.1 2200 EKYP-ERVPFRLTRMLTFAMEVSNIEGSYRITCEAVMRVIRENKDSLMAVLEAFIHDPLINWR 2261
                      ****.*********************************************************7 PP

>> DUF3385  Domain of unknown function (DUF3385)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       2.7   2.2e+03      94     130 ..     312     349 ..     265     356 .. 0.49
   2 !   13.7   0.0   5.3e-05     0.044      58     158 ..     632     730 ..     581     731 .. 0.74
   3 !  204.4   0.4   1.2e-63   9.7e-61       1     161 []     735     895 ..     735     895 .. 0.97
   4 ?   -1.0   0.4       1.8   1.5e+03      79     136 ..    1018    1073 ..     981    1089 .. 0.59

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 2.7
     DUF3385  94 ilkdpsls.shhaavveaimnifktlglkcvpfLdqii 130
                  l+ +  + + ++a+  ai +i + +g+   ++Ld ii
  EEA20937.1 312 YLQAQLKReKERNAAFIAIGKIANAVGVAIGQYLDAII 349
                 22222222244455555666666666666666666665 PP

  == domain 2  score: 13.7 bits;  conditional E-value: 5.3e-05
     DUF3385  58 rreeaaretdlsllmvglspsneeyyptvvinaLlrilkdpslsshhaavveaimnifktlglkcvpfLdqiipallsvirtteesnlrefllqqLatL 156
                  r+++++++ +sl++ + ++    y    +i++Ll    dps +   +++++ai    +  g+++ ++++q++p +l  +++ +++  re  l+ L++L
  EEA20937.1 632 ARQKEESAQLISLFVANATKLIRSYVDP-MITSLLPKTTDPSAN-VASTTLRAIGELANIGGSEMKTYIPQLMPIILDSLQDLSSHAKREAALRTLGQL 728
                 3344445566777888888887777655.8999999999***66.889999********99************************************99 PP

     DUF3385 157 vs 158
                  s
  EEA20937.1 729 AS 730
                 75 PP

  == domain 3  score: 204.4 bits;  conditional E-value: 1.2e-63
     DUF3385   1 VvdPyleypqLLelLlnilkteqsqsirrevikllGilGALDPykhkqveeraedkkrreeaaretdlsllmvglspsneeyyptvvinaLl.rilkdp 98 
                 V++Py+eypqLL +L+ni+kteq +s+r+e+ikllGilGALDPyk++q++e ++d +  +e ++ +d++l+m+gl+ps+eeyyptvvin+Ll +il+++
  EEA20937.1 735 VIEPYMEYPQLLAVLINIIKTEQAGSLRKETIKLLGILGALDPYKYQQISEISPDVRYINEVQPISDVALIMQGLTPSSEEYYPTVVINTLLqNILREN 833
                 9**************************************************9***9888888889**************************978***** PP

     DUF3385  99 slsshhaavveaimnifktlglkcvpfLdqiipallsvirtteesnlrefllqqLatLvsivk 161
                 sl+++h+av++ai++ifktlglkcv+fL qiip +l vir+++   ++e++++qLa+Lv+iv+
  EEA20937.1 834 SLAQYHSAVIDAIVTIFKTLGLKCVSFLGQIIPGFLGVIRSSPV-GRLESYFNQLAILVNIVR 895
                 ****************************************9876.*****************7 PP

  == domain 4  score: -1.0 bits;  conditional E-value: 1.8
     DUF3385   79 neeyyptvvinaLlrilkdpslsshhaavveaimnifktlglkcvpfLdqiipallsv 136 
                  n   +++ +i++L r++  +  ++ ++a+++ i   + +lg   + +++ +i+++++ 
  EEA20937.1 1018 NVSDFASLMIHSLSRVIASND-RTLQKAAMDCICALIFQLGQDFTHYIQ-LINKVMKQ 1073
                  444467778999999884444.334555666665444446666665553.33444443 PP

>> FRB_dom  FKBP12-rapamycin binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.3       6.2     5e+03      39      89 ..    1069    1134 ..    1051    1140 .. 0.55
   2 ?    2.3   0.4      0.27   2.2e+02      43      80 ..    1291    1327 ..    1253    1332 .. 0.72
   3 !  137.8   0.2   1.6e-43   1.3e-40       1      98 [.    1846    1943 ..    1846    1944 .. 0.99

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 6.2
     FRB_dom   39 plhellekgpetlreasFaqafgreLkeaeewlkky...............kkteneedlnqawdi 89  
                  + +++ + ++++++    + + g++L +  ++ ++y               k + n+++l++awd 
  EEA20937.1 1069 KVMKQHQVTNSSYESYVVKLQKGESLPQDLTLHENYrtladdtnyaeigqkKMQVNQQHLKNAWDA 1134
                  444444444444444444445555555555555555555555555555544556677778888875 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.27
     FRB_dom   43 llekgpetlreasFaqafgreLkeaeewlkkykktene 80  
                   l+ +++ +r+++ ++++ ++L++ ee+l  yk+ e++
  EEA20937.1 1291 ILR-KAQAYRDVELKETWFEKLQRWEEALAAYKRREKQ 1327
                  233.589*************************888765 PP

  == domain 3  score: 137.8 bits;  conditional E-value: 1.6e-43
     FRB_dom    1 ELiRvAilwhElwhegLeeAsrlyfgeknveamlklleplhellekgpetlreasFaqafgreLkeaeewlkkykkteneedlnqawdiyyevfrri 97  
                  ELiRvA+lwhElwhegLeeAsrlyfg++nve+m+++l plhell++g++tlre+sF+qafgr+L ea++++  y++te+  dlnqaw++yy+vfr+i
  EEA20937.1 1846 ELIRVAVLWHELWHEGLEEASRLYFGDHNVEGMFSTLAPLHELLDRGAQTLREVSFTQAFGRDLAEARQYCLLYRETEELGDLNQAWELYYNVFRKI 1942
                  9***********************************************************************************************9 PP

     FRB_dom   98 k 98  
                   
  EEA20937.1 1943 A 1943
                  6 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.1   0.5    0.0044       3.6      29      84 ..      95     160 ..      87     164 .. 0.78
   2 ?    3.4   0.2      0.12     1e+02       4      57 ..     143     206 ..     140     216 .. 0.70
   3 ?   -1.4   0.0       3.9   3.2e+03       8      55 ..     274     290 ..     264     334 .. 0.70
   4 ?    2.9   0.0      0.18   1.4e+02      19      53 ..     474     514 ..     464     519 .. 0.79
   5 !   21.8   0.0   2.2e-07   0.00018       2      71 ..     542     619 ..     541     621 .. 0.84
   6 !   17.0   0.0   6.9e-06    0.0056       3      87 ..     663     769 ..     661     770 .. 0.73
   7 ?    3.6   0.0       0.1        85      34      73 ..     987    1028 ..     979    1042 .. 0.78
   8 ?    4.8   0.1     0.045        37       2      33 ..    1771    1803 ..    1761    1842 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0044
      HEAT_2  29 npealpaLvellededpavRraaaeaLgaig..........dpealpaLkellddddddvvReaAa 84 
                 +++   +L+++l++ d av   aa++Lg+++           ++ +++ +e+l++++ + +R aA+
  EEA20937.1  95 TTRFASYLRSALRSNDNAVLVYAARSLGRLAkpggaltaelVESEIQSALEWLQSERQESRRFAAV 160
                 556678999******************999533345544333668999999999999999999997 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.12
      HEAT_2   4 LlqalendpdpevrraairaLg..rignp........ealpaLvellededpavRraaaeaLga 57 
                  l+ l++   +  r aa+  +    +g+p        ++++++  +l+d++  +R++aaea ++
  EEA20937.1 143 ALEWLQSERQESRRFAAVLIIRelAKGSPtllygfvsQIFDLVWVALRDPKVLIRETAAEAVSE 206
                 56777544444445577777773333556666666656677777788**************987 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 3.9
      HEAT_2   8 lendpdpevrraairaLgrignpealpaLvellededpavRraaaeaL 55 
                 l+++ d                               p +R ++++++
  EEA20937.1 274 LKDHRD-------------------------------PKIRTQVVRTI 290
                 344444...............................55555555443 PP

  == domain 4  score: 2.9 bits;  conditional E-value: 0.18
      HEAT_2  19 aairaLg......rignpealpaLvellededpavRraaae 53 
                  a+++Lg       i n+ +++  ++++e+++p++R+a a 
  EEA20937.1 474 LALHTLGsfdfsgHILNEFVRDVAIRYVESDNPEIRKASAL 514
                 5788888666666667778899***************9876 PP

  == domain 5  score: 21.8 bits;  conditional E-value: 2.2e-07
      HEAT_2   2 daLlqalendpdpevrraairaLg.....rignpealpaLvellededpavRraaaeaLgaigd..pe.alpaLkell 71 
                 d+Ll + + dpdpe+rr+++ +L       ++ pe +++L+ +++de  avR+aa+  +g++ +  p+ + p L++ll
  EEA20937.1 542 DKLLTVGVGDPDPEIRRTVLLSLDrkfdrHLAKPENIRCLFLAVNDEVFAVREAAISIIGRLSSvnPAyVFPPLRKLL 619
                 677777789***************9887667889**************************998643443568888876 PP

  == domain 6  score: 17.0 bits;  conditional E-value: 6.9e-06
      HEAT_2   3 aLlqalendpdpevrraairaLg........rignp.....ealpaLvelled.edpavRraaaeaLgaig............dpealpaLkelldddd 75 
                  Ll    +dp+ +v+ +++ra+g        +         +++p++++ l+d ++ a R+aa ++Lg+++             p+ l++L  + ++++
  EEA20937.1 663 SLLPKT-TDPSANVASTTLRAIGelaniggsE---MktyipQLMPIILDSLQDlSSHAKREAALRTLGQLAsnsgyviepymeYPQLLAVLINIIKTEQ 757
                 567777.8***************666444442...04445599********9967889999999****9963333444333324889999999999988 PP

      HEAT_2  76 ddvvReaAaeaL 87 
                     R ++++ L
  EEA20937.1 758 AGSLRKETIKLL 769
                 887787777665 PP

  == domain 7  score: 3.6 bits;  conditional E-value: 0.1
      HEAT_2   34 paLvell.ededp.avRraaaeaLgaigdpealpaLkelldd 73  
                  p +v+l  + ++p ++R+ a+e+Lg++ ++ +++  + l+ +
  EEA20937.1  987 PSIVRLFdKVQNPlNIRKSAIETLGKLSREVNVSDFASLMIH 1028
                  666666644477768************998888777777765 PP

  == domain 8  score: 4.8 bits;  conditional E-value: 0.045
      HEAT_2    2 daLlqalendpdpevrraairaLg..rignpeal 33  
                  ++L++++ n p+++vr a+ r L+   +++p+al
  EEA20937.1 1771 PQLIARI-NQPNTKVRTAVHRLLAevGKAHPQAL 1803
                  5666666.66666666666666663323334433 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.1     0.059        48      31      55 .]     100     124 ..      71     124 .. 0.85
   2 !   13.3   0.0   0.00011     0.091       4      53 ..     156     205 ..     154     206 .. 0.94
   3 ?    0.3   0.0       1.4   1.1e+03       3      30 ..     322     349 ..     306     356 .. 0.74
   4 ?   -2.4   0.0         9   7.3e+03      26      49 ..     537     561 ..     527     564 .. 0.73
   5 !    7.6   0.1    0.0068       5.5       2      37 ..     591     626 ..     590     643 .. 0.83
   6 !   10.5   0.0   0.00084      0.68      16      55 .]     647     686 ..     632     686 .. 0.83
   7 !   20.8   0.0   4.9e-07    0.0004       8      55 .]     680     728 ..     679     728 .. 0.96
   8 !    9.8   0.0    0.0014       1.1       4      53 ..     718     770 ..     715     772 .. 0.92
   9 ?   -1.3   0.0       4.1   3.4e+03      10      45 ..     929     960 ..     925     962 .. 0.75
  10 ?    3.2   0.0      0.17   1.3e+02      16      55 .]     976    1013 ..     972    1013 .. 0.80
  11 ?    1.9   0.0       0.4   3.3e+02      29      52 ..    1769    1792 ..    1768    1795 .. 0.85

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.059
     HEAT_EZ  31 paLlalLnddsdeVRaaAagaLgnl 55 
                  +L ++L++ + +V  +Aa+ Lg+l
  EEA20937.1 100 SYLRSALRSNDNAVLVYAARSLGRL 124
                 68999******************97 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 0.00011
     HEAT_EZ   4 RraAawaLGrlaggepellqplvpeilpaLlalLnddsdeVRaaAagaLg 53 
                 R+aA++ + +la g p ll ++v++i ++   +L+d++ ++R++Aa a +
  EEA20937.1 156 RFAAVLIIRELAKGSPTLLYGFVSQIFDLVWVALRDPKVLIRETAAEAVS 205
                 9*******77************************9999999*****9965 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 1.4
     HEAT_EZ   3 vRraAawaLGrlaggepellqplvpeil 30 
                 +R+aA  a+G +a+  + ++ +++++i+
  EEA20937.1 322 ERNAAFIAIGKIANAVGVAIGQYLDAII 349
                 4556666888888888888888877777 PP

  == domain 4  score: -2.4 bits;  conditional E-value: 9
     HEAT_EZ  26 vpeilpaLl.alLnddsdeVRaaAa 49 
                 v e+++ Ll  +  d+++e+R +++
  EEA20937.1 537 VGEVIDKLLtVGVGDPDPEIRRTVL 561
                 556777777577799999**99886 PP

  == domain 5  score: 7.6 bits;  conditional E-value: 0.0068
     HEAT_EZ   2 rvRraAawaLGrlaggepellqplvpeilpaLlalL 37 
                 +vR+aA++ +Grl +++p ++ p + ++l  Ll +L
  EEA20937.1 591 AVREAAISIIGRLSSVNPAYVFPPLRKLLVNLLTGL 626
                 69******************8888888777776555 PP

  == domain 6  score: 10.5 bits;  conditional E-value: 0.00084
     HEAT_EZ  16 ggepellqplvpeilpaLlalLnddsdeVRaaAagaLgnl 55 
                 +++  l++ +v+ ++  Ll+  +d+s++V  ++++a+g l
  EEA20937.1 647 ANATKLIRSYVDPMITSLLPKTTDPSANVASTTLRAIGEL 686
                 467789999*****************************86 PP

  == domain 7  score: 20.8 bits;  conditional E-value: 4.9e-07
     HEAT_EZ   8 awaLGrlaggepellqplvpeilpaLlalLnddsdeV.RaaAagaLgnl 55 
                 ++a+G+la+ ++  +++++p+++p  l  L+d s++  R+aA+++Lg+l
  EEA20937.1 680 LRAIGELANIGGSEMKTYIPQLMPIILDSLQDLSSHAkREAALRTLGQL 728
                 68******************************999999*********97 PP

  == domain 8  score: 9.8 bits;  conditional E-value: 0.0014
     HEAT_EZ   4 RraAawaLGrlaggepellqp..lvpeilpaLlalLnddsd.eVRaaAagaLg 53 
                 R+aA+++LG la++ +  ++p  + p++l+ L++  +++++ + R+ ++  Lg
  EEA20937.1 718 REAALRTLGQLASNSGYVIEPymEYPQLLAVLINIIKTEQAgSLRKETIKLLG 770
                 9***********999999999******************99999999998888 PP

  == domain 9  score: -1.3 bits;  conditional E-value: 4.1
     HEAT_EZ  10 aLGr.laggepellqplvpeilpaLlalLnddsdeVR 45 
                 a+++ l+g+ + +l++l+p +l+ L      ++ + R
  EEA20937.1 929 AISTaLEGEFKKYLAGLIPLMLDTLE-----KDISPR 960
                 77777788888889999998888888.....666665 PP

  == domain 10  score: 3.2 bits;  conditional E-value: 0.17
     HEAT_EZ   16 ggepellqplvpeilpaLlalLnddsd...eVRaaAagaLgnl 55  
                  + + e+++++vp i++++      + +   ++R+ A+ +Lg+l
  EEA20937.1  976 SSGEEYMHLVVPSIVRLFD-----KVQnplNIRKSAIETLGKL 1013
                  678899*************.....6664236699999999987 PP

  == domain 11  score: 1.9 bits;  conditional E-value: 0.4
     HEAT_EZ   29 ilpaLlalLnddsdeVRaaAagaL 52  
                  + p+L+a+ n ++ +VR+a+ + L
  EEA20937.1 1769 VTPQLIARINQPNTKVRTAVHRLL 1792
                  679***************985555 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.1      0.35   2.9e+02       5      29 ..     102     126 ..      99     126 .. 0.89
   2 ?    0.6   0.0       1.2   9.4e+02       6      30 ..     144     169 ..     140     170 .. 0.81
   3 !    7.3   0.0    0.0082       6.7       1      29 [.     181     209 ..     181     211 .. 0.87
   4 ?    1.6   0.0      0.55   4.5e+02       5      30 ..     271     296 ..     268     297 .. 0.82
   5 ?    5.2   0.0     0.037        30       9      27 ..     501     519 ..     493     522 .. 0.87
   6 ?    4.1   0.0     0.087        71       8      24 ..     548     564 ..     541     566 .. 0.82
   7 !    9.1   0.1    0.0022       1.8       5      29 ..     581     605 ..     578     606 .. 0.85
   8 ?    4.2   0.0     0.082        67       8      29 ..     667     688 ..     661     689 .. 0.85
   9 !   17.1   0.0   5.8e-06    0.0047       1      30 [.     701     731 ..     701     732 .. 0.92
  10 ?    3.5   0.0      0.13   1.1e+02       2      28 ..     986    1014 ..     985    1017 .. 0.75
  11 ?    1.6   0.0      0.56   4.6e+02       3      28 ..    1771    1796 ..    1769    1799 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.35
                 HHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   5 llkllsDpspeVReaAakaLgalae 29 
                 l ++l++++  V   Aa++Lg+la+
  EEA20937.1 102 LRSALRSNDNAVLVYAARSLGRLAK 126
                 6678999****************96 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 1.2
                 HHHHT-SSHH.HHHHHHHHHHHHHHC CS
        HEAT   6 lkllsDpspe.VReaAakaLgalaev 30 
                 l++l+++  e  R aA++ + +la++
  EEA20937.1 144 LEWLQSERQEsRRFAAVLIIRELAKG 169
                 678877777747***********986 PP

  == domain 3  score: 7.3 bits;  conditional E-value: 0.0082
                 HHHHHHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgalae 29 
                 +++l++ +l+Dp   +Re+Aa+a+ +  e
  EEA20937.1 181 IFDLVWVALRDPKVLIRETAAEAVSECFE 209
                 56789999***************988765 PP

  == domain 4  score: 1.6 bits;  conditional E-value: 0.55
                 HHHHHT-SSHHHHHHHHHHHHHHHHC CS
        HEAT   5 llkllsDpspeVReaAakaLgalaev 30 
                 +l+l  + +p++R  +++++  la++
  EEA20937.1 271 VLRLKDHRDPKIRTQVVRTIPILASY 296
                 6776677************9888875 PP

  == domain 5  score: 5.2 bits;  conditional E-value: 0.037
                 HT-SSHHHHHHHHHHHHHH CS
        HEAT   9 lsDpspeVReaAakaLgal 27 
                  ++++pe+R+a+a+++++l
  EEA20937.1 501 VESDNPEIRKASALTCCQL 519
                 6789************998 PP

  == domain 6  score: 4.1 bits;  conditional E-value: 0.087
                 HHT-SSHHHHHHHHHHH CS
        HEAT   8 llsDpspeVReaAakaL 24 
                    Dp+pe+R++++++L
  EEA20937.1 548 GVGDPDPEIRRTVLLSL 564
                 568**********9988 PP

  == domain 7  score: 9.1 bits;  conditional E-value: 0.0022
                 HHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   5 llkllsDpspeVReaAakaLgalae 29 
                 l  + +D+   VReaA+  +g+l++
  EEA20937.1 581 LFLAVNDEVFAVREAAISIIGRLSS 605
                 45557*****************997 PP

  == domain 8  score: 4.2 bits;  conditional E-value: 0.082
                 HHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   8 llsDpspeVReaAakaLgalae 29 
                   +Dps++V +++++a+g+la 
  EEA20937.1 667 KTTDPSANVASTTLRAIGELAN 688
                 568*****************95 PP

  == domain 9  score: 17.1 bits;  conditional E-value: 5.8e-06
                 HHHHHHHHHT-.SSHHHHHHHHHHHHHHHHC CS
        HEAT   1 llPlllkllsD.pspeVReaAakaLgalaev 30 
                 l+P++l  l+D +s   ReaA+++Lg+la++
  EEA20937.1 701 LMPIILDSLQDlSSHAKREAALRTLGQLASN 731
                 8**********877779************86 PP

  == domain 10  score: 3.5 bits;  conditional E-value: 0.13
                  HHHHHHHH.T-SSHH.HHHHHHHHHHHHH CS
        HEAT    2 lPlllkll.sDpspe.VReaAakaLgala 28  
                  +P +++l  + ++p  +R++A+++Lg+l+
  EEA20937.1  986 VPSIVRLFdKVQNPLnIRKSAIETLGKLS 1014
                  56666654444777779*********997 PP

  == domain 11  score: 1.6 bits;  conditional E-value: 0.56
                  HHHHHHHT-SSHHHHHHHHHHHHHHH CS
        HEAT    3 PlllkllsDpspeVReaAakaLgala 28  
                  P l+  ++ p+ +VR a+ + L+++ 
  EEA20937.1 1771 PQLIARINQPNTKVRTAVHRLLAEVG 1796
                  88999999*********998888765 PP

>> FATC  FATC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.1       2.1   1.7e+03      13      24 ..    2101    2112 ..    2098    2112 .. 0.90
   2 !   49.5   1.0   3.3e-16   2.7e-13       2      32 .]    2352    2382 .]    2351    2382 .] 0.98

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 2.1
        FATC   13 keATdpeNLaqm 24  
                  ++A d +NL+ m
  EEA20937.1 2101 QMAPDYDNLSLM 2112
                  89********98 PP

  == domain 2  score: 49.5 bits;  conditional E-value: 3.3e-16
        FATC    2 LsveqQVdrLIkeATdpeNLaqmyiGWcPww 32  
                  L v++QVd+L  +AT++eN +q++iGWc +w
  EEA20937.1 2352 LNVSDQVDKLLAQATSVENICQHWIGWCSFW 2382
                  89***************************** PP

>> UME  UME (NUC010) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0      0.61   4.9e+02      21      65 ..      66     109 ..      47     118 .. 0.79
   2 ?    1.3   0.0       0.4   3.3e+02      23      98 ..     277     352 ..     268     355 .. 0.80
   3 !    8.3   0.0    0.0025       2.1      30      73 ..     677     723 ..     660     772 .. 0.82
   4 ?    0.6   0.0      0.64   5.2e+02      30      82 ..     840     894 ..     820     913 .. 0.46
   5 ?    1.3   0.0       0.4   3.2e+02      31      64 ..     882     915 ..     868     945 .. 0.72
   6 ?   -0.0   0.1         1   8.2e+02      25      83 ..     999    1057 ..     979    1071 .. 0.63
   7 ?   -0.1   0.1       1.1     9e+02      25      88 ..    1139    1202 ..    1121    1210 .. 0.64

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.61
         UME  21 hgkkslaekkraikaleeliklagssissalpqimacLqsaleid 65 
                  g+ + +ek+  + al +li + g  ++   ++  + L+sal+++
  EEA20937.1  66 TGS-DANEKIGGLLALDRLIDFDGVDAAQKTTRFASYLRSALRSN 109
                 344.889**********************************9985 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.4
         UME  23 kkslaekkraikaleeliklagss.issalpqimacLqsaleidelrsaalsvWatllsnlededleplleqtfali 98 
                  ++++ + ++++ +  l ++a +   + +l + m+ Lq  l+ ++ r+aa+ +    ++ + + +++++l+++++ i
  EEA20937.1 277 HRDPKIRTQVVRTIPILASYAPTDfTNNYLHRFMVYLQAQLKREKERNAAFIAIGKIANAVGV-AIGQYLDAIIVYI 352
                 44677899999999999999999988999*******************999887777776665.4666666666665 PP

  == domain 3  score: 8.3 bits;  conditional E-value: 0.0025
         UME  30 kraikaleeliklagssissalpqimacLqsalei...delrsaals 73 
                   +++a++el ++ gs++++++pq+m +  + l++    + r+aal+
  EEA20937.1 677 STTLRAIGELANIGGSEMKTYIPQLMPIILDSLQDlssHAKREAALR 723
                 5689********************99998888876433445555555 PP

  == domain 4  score: 0.6 bits;  conditional E-value: 0.64
         UME  30 kraikaleeliklagssissalpqimacLqsaleid..elrsaalsvWatllsnl 82 
                   +i a+  ++k +g +  s+l qi+  +   +++   +  +  ++  a+l++++
  EEA20937.1 840 SAVIDAIVTIFKTLGLKCVSFLGQIIPGFLGVIRSSpvGRLESYFNQLAILVNIV 894
                 5566666666666666666666666443333333321111222333333333332 PP

  == domain 5  score: 1.3 bits;  conditional E-value: 0.4
         UME  31 raikaleeliklagssissalpqimacLqsalei 64 
                  + + l  l+++++++i+ +lp i+ + ++  ++
  EEA20937.1 882 SYFNQLAILVNIVRQHIRAFLPEIIDTIRDYWDS 915
                 56778999**************877776665555 PP

  == domain 6  score: -0.0 bits;  conditional E-value: 1
         UME   25 slaekkraikaleeliklagssissalpqimacLqsalei..delrsaalsvWatllsnle 83  
                  +l+ +k ai+ l++l + ++  +s ++  ++  L   +++    l++aa+++  +l+ +l 
  EEA20937.1  999 PLNIRKSAIETLGKLSREVN--VSDFASLMIHSLSRVIASndRTLQKAAMDCICALIFQLG 1057
                  66777777777777766654..444444444555554444336888889888888887775 PP

  == domain 7  score: -0.1 bits;  conditional E-value: 1.1
         UME   25 slaekkraikaleeliklagssissalpqi..macLqsaleidelrsaalsvWatllsnlededle 88  
                  + +++++ i+  +  ++l+++s s+al     +a   + l++d ++ a +s+W +l  + ++e + 
  EEA20937.1 1139 TREDWQEWIRRFS--VELLKESPSPALRACasLAGIYQPLAKDLFNAAFVSCWTELYDQYQEELVR 1202
                  5556666666655..56666665555543211333445677888999999*****99988877655 PP

>> Sec7_N  Guanine nucleotide exchange factor in Golgi transport N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   0.0   0.00011     0.087      58     149 ..     650     742 ..     641     744 .. 0.87
   2 ?   -0.0   0.0      0.91   7.4e+02      99     136 ..     893     931 ..     878     962 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 0.00011
      Sec7_N  58 lqllkqklcplLlknls..espsfpvferslrivllLlkkfrseLktEievflsllilillesdsslwqrvlaLeilrrlcsdpqllvelylnY 149
                 ++l+++++ p+++ +l   + ps +v + +lr +  L +   se+kt i  ++  ++  l +  ss  +r+ aL++l +l s++  ++e y++Y
  EEA20937.1 650 TKLIRSYVDPMITSLLPktTDPSANVASTTLRAIGELANIGGSEMKTYIPQLMPIILDSL-QDLSSHAKREAALRTLGQLASNSGYVIEPYMEY 742
                 678999999999999954455567799999999999999999999999999999999999.778889************************999 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 0.91
      Sec7_N  99 eLktEievflsllililles.dsslwqrvlaLeilrrlc 136
                  + + i +fl ++i  + +  ds+ + ++++L +++ ++
  EEA20937.1 893 IVRQHIRAFLPEIIDTIRDYwDSNHQVQATILSLIEAIS 931
                 455667888888888884448888888888888777765 PP

>> CLASP_N  CLASP N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0      0.49     4e+02      76     123 ..     162     209 ..     150     234 .. 0.64
   2 !    7.8   0.0    0.0027       2.2     143     195 ..     505     559 ..     491     562 .. 0.77
   3 ?    2.5   0.0      0.12        94      63     126 ..     669     733 ..     642     743 .. 0.77
   4 ?   -0.5   0.3      0.93   7.6e+02      51      96 ..    1026    1068 ..    1001    1078 .. 0.65
   5 ?   -2.3   0.1       3.3   2.7e+03     111     162 ..    1785    1833 ..    1767    1849 .. 0.52

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.49
     CLASP_N  76 llkelaiqlkeqldpmveillptLlkllgdtKkiisqnanqalaalls 123
                 +++ela+   + l  +v +++++    l d K +i+++a+ a++  ++
  EEA20937.1 162 IIRELAKGSPTLLYGFVSQIFDLVWVALRDPKVLIRETAAEAVSECFE 209
                 556666666666666666666666666666666666666666655443 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0027
     CLASP_N 143 nvqpReysaiwLkilltrfeshkskleaslll..dliekslkkgleDanptVRet 195
                 n+++R  sa    +l+ + ++ +++ ++s  +  + i+k+l+ g+ D++p++R+t
  EEA20937.1 505 NPEIRKASALTCCQLFVHDPIINQTSSHSIQVvgEVIDKLLTVGVGDPDPEIRRT 559
                 78888888888888888888444444444433349******************97 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.12
     CLASP_N  63 ssLrttlsstgchllkelaiqlkeqldpmveillptLlkllgdtKkii.sqnanqalaallsnas 126
                 ++ +  + st +  + ela + +++++ ++ +l+p++l+ l+d    + +++a  +l +l sn +
  EEA20937.1 669 TDPSANVASTTLRAIGELANIGGSEMKTYIPQLMPIILDSLQDLSSHAkREAALRTLGQLASNSG 733
                 4555678899999***************************9997766515555667777777766 PP

  == domain 4  score: -0.5 bits;  conditional E-value: 0.93
     CLASP_N   51 lkqlleailkalssLrttlsstgchllkelaiqlkeqldpmveill 96  
                  +   ++ +++ ++s   tl ++++  ++ l+ ql++++ ++++ + 
  EEA20937.1 1026 M---IHSLSRVIASNDRTLQKAAMDCICALIFQLGQDFTHYIQLIN 1068
                  2...366666666666677777777777777777777777666654 PP

  == domain 5  score: -2.3 bits;  conditional E-value: 3.3
     CLASP_N  111 sqnanqalaallsnasfspri.lqvlsvalqdKnvqpReysaiwLkilltrfe 162 
                  +++ +  la + ++    p+  +  ++va++  nv  R+ sa+++   +++++
  EEA20937.1 1785 RTAVHRLLAEVGKAH---PQAlVYPVTVAIKS-NVARRSQSATYIMESMRQHS 1833
                  333333333333333...33335666666665.77777777777666666665 PP

>> Vac14_Fab1_bd  Vacuolar 14 Fab1-binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.62     5e+02      27      78 ..       9      61 ..       5      85 .. 0.74
   2 ?    1.5   0.0      0.57   4.6e+02      29      88 ..     140     200 ..     129     208 .. 0.75
   3 ?    0.5   0.1       1.2   9.4e+02       2      32 ..     322     352 ..     321     357 .. 0.91
   4 ?    1.6   0.0      0.54   4.4e+02      11      35 ..     376     400 ..     369     406 .. 0.89
   5 ?    0.7   0.0         1   8.4e+02      21      82 ..     653     714 ..     638     724 .. 0.55
   6 ?    0.7   0.0         1   8.3e+02      10      37 ..     927     954 ..     917     962 .. 0.83
   7 ?    0.6   0.0       1.1   8.6e+02      21      88 ..     978    1045 ..     968    1051 .. 0.76

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.62
  Vac14_Fab1_bd 27 eivkpvlkcfsDkdsrvRyyacEsly.niakvakgevlkllneifdalvklva 78
                   ++v+ +++ ++ k+++ R  a+  ly n+  v+++ + +++ e ++a+++ +a
     EEA20937.1  9 DVVQRLFTELKSKNEEARVRASYELYdNVLTVSRDWAPEKFLEFYNAVSQRIA 61
                   68888999999999999999999999889999998888888888887776554 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.57
  Vac14_Fab1_bd  29 vkpvlkcfsDkdsr.vRyyacEslyniakvakgevlkllneifdalvklvaDsdesvksga 88 
                    +++ l+ ++ + ++  R+ a+  +  +ak + + +  ++++ifd ++  + D +  ++++a
     EEA20937.1 140 IQSALEWLQSERQEsRRFAAVLIIRELAKGSPTLLYGFVSQIFDLVWVALRDPKVLIRETA 200
                    55556666554443046777778889999999999999********999999999998765 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 1.2
  Vac14_Fab1_bd   2 arkggligLaavaialekkikeyleeivkpv 32 
                    +r+++ i++  +a a++ +i +yl+ i+  +
     EEA20937.1 322 ERNAAFIAIGKIANAVGVAIGQYLDAIIVYI 352
                    799************************9765 PP

  == domain 4  score: 1.6 bits;  conditional E-value: 0.54
  Vac14_Fab1_bd  11 aavaialekkikeyleeivkpvlkc 35 
                      +++a+++++++y+e +++p+++c
     EEA20937.1 376 SMLSLAVGQALSKYMEALLDPIFAC 400
                    56799*****************998 PP

  == domain 5  score: 0.7 bits;  conditional E-value: 1
  Vac14_Fab1_bd  21 ikeyleeivkpvlkcfsDkdsrvRyyacEslyniakvakgevlkllneifdalvklvaDsde 82 
                    i++y++ +++++l   +D ++ v  ++  ++  +a +  +e+ +++ ++  ++   + D  +
     EEA20937.1 653 IRSYVDPMITSLLPKTTDPSANVASTTLRAIGELANIGGSEMKTYIPQLMPIILDSLQDLSS 714
                    56666666666666666666666655555555555544444444444444444444444433 PP

  == domain 6  score: 0.7 bits;  conditional E-value: 1
  Vac14_Fab1_bd  10 Laavaialekkikeyleeivkpvlkcfs 37 
                    + a++ ale + k+yl  +++ +l++++
     EEA20937.1 927 IEAISTALEGEFKKYLAGLIPLMLDTLE 954
                    5699********************9875 PP

  == domain 7  score: 0.6 bits;  conditional E-value: 1.1
  Vac14_Fab1_bd   21 ikeyleeivkpvlkcfsDkds..rvRyyacEslyniakvakgevlkllne.ifdalvklvaDsdesvksga 88  
                      +ey++ +v+++++ f+  ++   +R  a+E+l  +++ ++   ++ + + + + l++++a +d+ ++++a
     EEA20937.1  978 GEEYMHLVVPSIVRLFDKVQNplNIRKSAIETLGKLSREVN---VSDFASlMIHSLSRVIASNDRTLQKAA 1045
                     5789999*******99876653479999***9976665554...444443156889999999999998887 PP

>> MMS19_C  RNAPII transcription regulator C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.1      0.16   1.3e+02     360     421 ..     603     665 ..     596     666 .. 0.88
   2 ?   11.9   0.1   0.00011     0.086     368     414 ..     694     741 ..     683     752 .. 0.85
   3 ?    1.3   2.6      0.18   1.5e+02      49     222 ..     828    1053 ..     817    1088 .. 0.42

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.16
     MMS19_C 360 lkhvPkslllpeLptLlPlLlqaLdlpdae.vkastLetlksileespslvsehlssLvprLL 421
                 l++v ++++ p L +Ll  Ll++L   +++  k  + + ++  + ++ +l+ ++++  +++LL
  EEA20937.1 603 LSSVNPAYVFPPLRKLLVNLLTGLGFASTArQKEESAQLISLFVANATKLIRSYVDPMITSLL 665
                 89999*******************66555538899999999999999*************998 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 0.00011
     MMS19_C 368 llpeLptLlPlLlqaL.dlpdaevkastLetlksileespslvsehls 414
                 + +++p+L+P++l++L dl++ + + ++L tl  ++ +s  +++++++
  EEA20937.1 694 MKTYIPQLMPIILDSLqDLSSHAKREAALRTLGQLASNSGYVIEPYME 741
                 6789********************************999999998664 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.18
     MMS19_C   49 lvlksnessaayahailstllkllekkqtdlekeellnsyydrivprlltlvvsaastss...............................siltdd 114 
                   +l++n+  a+y  a+++++++++++    l    ++ s+  +i+p +l ++ s+  +                                    +++
  EEA20937.1  828 NILRENSL-AQYHSAVIDAIVTIFKTLG--L----KCVSFLGQIIPGFLGVIRSSPVGRLesyfnqlailvnivrqhiraflpeiidtirdYWDSNH 917 
                  45555554.6666677777777777755..4....56677777777777764444433223333333333222222222222222222222222222 PP

     MMS19_C  115 rllevlgriinlivrslssskqqevleevvalfltgdask.................kfeplsesas.esqkqli...................... 171 
                  ++ +++ ++i++i   l+ +                   +                 +++p ++ ++       +                      
  EEA20937.1  918 QVQATILSLIEAISTALEGE-------------------FkkylagliplmldtlekDISPRRQPSErI-----Lhtflifgssgeeymhlvvpsiv 990 
                  22222222222222222222...................122333222222222222233322222222.....12222244444444444445555 PP

     MMS19_C  172 .............ilftailaalrkevklpdlsellnellellaseaespflrlaylrllallv 222 
                                     l  l++ev+++d ++l+ + l   +  +++++l++a++++++ l+
  EEA20937.1  991 rlfdkvqnplnirKSAIETLGKLSREVNVSDFASLMIHSLS-RVIASNDRTLQKAAMDCICALI 1053
                  44444444442222222223344555555555555544444.3333456666666666666666 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.1     0.032        26       9      32 ..    1308    1329 ..    1303    1331 .. 0.81
   2 ?   -1.2   0.0       3.5   2.8e+03      11      24 ..    1411    1424 ..    1406    1436 .. 0.85
   3 ?    4.2   0.0     0.066        53       4      19 ..    1632    1647 ..    1631    1649 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.032
       TPR_7    9 ysrlGdyeeAielyeqsLaltkdp 32  
                  +++l+++eeA+  y++  +   dp
  EEA20937.1 1308 FEKLQRWEEALAAYKR--REKQDP 1329
                  678************9..666665 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 3.5
       TPR_7   11 rlGdyeeAielyeq 24  
                  +++++eeA+ + e+
  EEA20937.1 1411 NRNQFEEAAHYIEK 1424
                  6899*******998 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.066
       TPR_7    4 nLarlysrlGdyeeAi 19  
                   La  y ++G++++A+
  EEA20937.1 1632 LLAKSYLKQGEWQTAL 1647
                  599************8 PP

>> Spore_III_AB  Stage III sporulation protein AB (spore_III_AB)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   0.0    0.0064       5.2      99     157 ..     103     161 ..      87     163 .. 0.90
   2 ?   -0.4   0.1       1.3   1.1e+03      39      82 ..    1116    1159 ..    1099    1234 .. 0.71

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0064
                   GS---HHHHHHHHHHHHHHT--SHHHHHHHHHHHHHHHHHHHHHHHHHHHHT-XXXXXX CS
  Spore_III_AB  99 klaLkkedkeilkelgeslgysdregqlkalelaleeleeeieeareeakkkeklyrtl 157
                   ++aL  +d ++l   ++slg++ + g   + el+++e++  +e ++ e+++  + +  l
    EEA20937.1 103 RSALRSNDNAVLVYAARSLGRLAKPGGALTAELVESEIQSALEWLQSERQESRRFAAVL 161
                   68999**********************************************99977655 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 1.3
                    HHHHHHHH-SS-HHHHHHHHHHCS-TTHHHHHHHHHHHHH.STS CS
  Spore_III_AB   39 llegeirygatpLpealeklaeksesplseffeevaerleekeg 82  
                    + + +++ ++  L++a    +++++++++e++++++ +l +++ 
    EEA20937.1 1116 IGQKKMQVNQQHLKNAWDASQKSTREDWQEWIRRFSVELLKESP 1159
                    55667777777777777778888888888888888777765332 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.4       2.8   2.3e+03      33      60 ..    1260    1286 ..    1255    1298 .. 0.68
   2 ?    6.5   0.0     0.014        12       5      42 ..    1312    1349 ..    1310    1350 .. 0.92
   3 ?   -1.8   0.0       5.7   4.7e+03      25      51 ..    1511    1537 ..    1507    1540 .. 0.85
   4 ?    3.1   0.1      0.17   1.4e+02      25      67 ..    1553    1596 ..    1552    1597 .. 0.92
   5 ?    1.6   0.0      0.48   3.9e+02      27      46 ..    1629    1648 ..    1623    1649 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 2.8
      TPR_19   33 eallalgqldeAealLdalpeedpddar 60  
                  e+ +++ q   A ++L ++ ++ +++ +
  EEA20937.1 1260 ELEFEQDQNSSAVEALITINNQLQQS-D 1286
                  56677778888888888888888773.2 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.014
      TPR_19    5 gdyaeAlalleqalqedpknaearllLAeallalgqld 42  
                  ++ +eAla++++  ++dp++  + ++ +++l alg+++
  EEA20937.1 1312 QRWEEALAAYKRREKQDPDSFGITMGKMRCLHALGEWK 1349
                  57899*******9999*******************985 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 5.7
      TPR_19   25 aearllLAeallalgqldeAealLdal 51  
                   + ++ +A+++ ++++   Ae++L+ l
  EEA20937.1 1511 MDMLIKYANLCRKSNRMGIAERTLASL 1537
                  5677789*****************987 PP

  == domain 4  score: 3.1 bits;  conditional E-value: 0.17
      TPR_19   25 aearllLAeallalgqldeAealLdalpeedpdd.aryasLlAk 67  
                  +e++++  +  +a+g+  +A + L++   + +dd  ry +LlA 
  EEA20937.1 1553 PEVKYARFKFAWAQGHQVDALQSLKEFTSALADDlTRYNALLAN 1596
                  578888889999******************************95 PP

  == domain 5  score: 1.6 bits;  conditional E-value: 0.48
      TPR_19   27 arllLAeallalgqldeAea 46  
                  ++ lLA+ +l++g+++ A +
  EEA20937.1 1629 LKKLLAKSYLKQGEWQTALQ 1648
                  6779***********99976 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.2     0.054        44      12      26 ..    1309    1323 ..    1307    1331 .. 0.84
   2 ?    2.4   0.1      0.26   2.1e+02       9      27 ..    1407    1425 ..    1406    1426 .. 0.86
   3 ?    3.7   0.1     0.097        79       6      22 ..    1632    1648 ..    1628    1649 .. 0.89

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.054
       TPR_2   12 yklgdyeeAleafek 26  
                  +kl+++eeAl+a+++
  EEA20937.1 1309 EKLQRWEEALAAYKR 1323
                  689**********98 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.26
       TPR_2    9 layyklgdyeeAleafekA 27  
                   ++++++++eeA+++ ek+
  EEA20937.1 1407 ILAINRNQFEEAAHYIEKV 1425
                  567899*********9995 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.097
       TPR_2    6 nlGlayyklgdyeeAle 22  
                   l+++y+k+g+++ Al+
  EEA20937.1 1632 LLAKSYLKQGEWQTALQ 1648
                  69***********9986 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   0.0    0.0038       3.1       7      28 ..    1311    1332 ..    1309    1334 .. 0.89
   2 ?   -0.6   0.0       1.4   1.1e+03       2      15 ..    1635    1648 ..    1634    1649 .. 0.87
   3 ?    1.2   0.2      0.38   3.1e+02      14      39 ..    1661    1686 ..    1659    1688 .. 0.88

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0038
      TPR_11    7 qGkyeeAieaYkkAlkldPdna 28  
                  ++++eeA++aYk+  k dPd+ 
  EEA20937.1 1311 LQRWEEALAAYKRREKQDPDSF 1332
                  689***********99999975 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 1.4
      TPR_11    2 dayyeqGkyeeAie 15  
                  + y +qG++  A++
  EEA20937.1 1635 KSYLKQGEWQTALQ 1648
                  5799********98 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.38
      TPR_11   14 ieaYkkAlkldPdnaeayynLGlayy 39  
                  ++aY++A +++ d+  a++  +la +
  EEA20937.1 1661 LNAYSAATQYNRDSYKAWHSWALANF 1686
                  689***********999999888876 PP

>> RTP1_C1  Required for nuclear transport of RNA pol II C-terminus 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.0       1.1   9.3e+02      18      70 ..      75     127 ..      67     162 .. 0.87
   2 ?    4.6   0.0     0.045        37       1      84 [.     227     318 ..     227     343 .. 0.85
   3 ?   -0.0   0.0       1.2   9.8e+02       7      54 ..     667     714 ..     662     756 .. 0.76
   4 ?   -2.9   0.0       9.6   7.8e+03      33      70 ..     959     995 ..     943    1000 .. 0.73
   5 ?   -2.0   0.1       4.7   3.9e+03      13      76 ..    1000    1061 ..     989    1095 .. 0.66

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 1.1
     RTP1_C1  18 hglvlLrkliekkskeavldiekilkllleaLkdedsYvYLnaikgLvaLadv 70 
                  gl+ L +li     +a+++ ++ ++ l +aL+ +d  v + a + L  La+ 
  EEA20937.1  75 GGLLALDRLIDFDGVDAAQKTTRFASYLRSALRSNDNAVLVYAARSLGRLAKP 127
                 69999******9999999*******************9999999999999875 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.045
     RTP1_C1   1 lqealkdlqdpllpvrahglvlLrkliekkskeavldiekilkllleaLkdedsYvYLnaikgLvaLadvfpeevlklLleey........e 84 
                 ++e l+ l+++ +      l+ Lr+l+ k      ++ ++  +++l+   + d+ +  ++++++  La++ p+++++  l+++        +
  EEA20937.1 227 YEESLQGLRSSNVDWIHGSLLILRELLLKGAMFMNEHYRNACEIVLRLKDHRDPKIRTQVVRTIPILASYAPTDFTNNYLHRFmvylqaqlK 318
                 5677888899999999999********************************************************99999999777654331 PP

  == domain 3  score: -0.0 bits;  conditional E-value: 1.2
     RTP1_C1   7 dlqdpllpvrahglvlLrkliekkskeavldiekilkllleaLkdeds 54 
                 + +dp + v +  l+ + +l++   +e ++ i++++ ++l++L+d  s
  EEA20937.1 667 KTTDPSANVASTTLRAIGELANIGGSEMKTYIPQLMPIILDSLQDLSS 714
                 567888888888888888888888888888888888888888888655 PP

  == domain 4  score: -2.9 bits;  conditional E-value: 9.6
     RTP1_C1  33 eavldiekilkllleaLkdedsYvYLnaikgLvaLadv 70 
                   ++  e+il+++l   +  ++Y++L ++  +v L d+
  EEA20937.1 959 PRRQPSERILHTFLIFGSSGEEYMHL-VVPSIVRLFDK 995
                 45677889999999999999***999.56666666665 PP

  == domain 5  score: -2.0 bits;  conditional E-value: 4.7
     RTP1_C1   13 lpvrahglvlLrkliekkskeavldiekilkllleaLkdedsYvYLnaikgLvaLadvfpeevl 76  
                  l +r  ++ +L kl ++ +      ++ +++ l + ++ +d  +  +a+ +++aL+    ++++
  EEA20937.1 1000 LNIRKSAIETLGKLSREVN--VSDFASLMIHSLSRVIASNDRTLQKAAMDCICALIFQLGQDFT 1061
                  4678888888888888776..6666666677777777777777777777777777766655544 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       9.4   7.7e+03      32      52 ..     257     276 ..     252     284 .. 0.75
   2 ?    3.1   0.2      0.14   1.1e+02      35      72 ..    1310    1348 ..    1249    1349 .. 0.71
   3 ?    0.1   0.0       1.2   9.6e+02      21      52 ..    1397    1429 ..    1389    1447 .. 0.75
   4 ?    3.2   0.1      0.13   1.1e+02      28      43 ..    1632    1647 ..    1627    1650 .. 0.77

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 9.4
                 HHHHTT-HHHHHHHHHCTSHH CS
      ANAPC3  32 clylngqykrAyellrkakln 52 
                 +++ n+ y  A+e++ ++ ++
  EEA20937.1 257 AMFMNEHYRNACEIVLRL-KD 276
                 678999999999999988.33 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.14
                  HTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-H CS
      ANAPC3   35 lngqykrAyellrka.klnskslgcrylfAqcllkLkky 72  
                  +++++++A+  +++  k+++ s g+ + + +cl +L+++
  EEA20937.1 1310 KLQRWEEALAAYKRReKQDPDSFGITMGKMRCLHALGEW 1348
                  445677777777777777777777777777777777766 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 1.2
                  --HHHHHHHHHHHHHTT-HHHHHHHHHCT.SHH CS
      ANAPC3   21 espedayllAlclylngqykrAyellrka.kln 52  
                  + p+ +++ A    +++q+++A ++++k  +  
  EEA20937.1 1397 HTPDRSFFGAILAINRNQFEEAAHYIEKVrNGL 1429
                  5566677777778899999***99999994443 PP

  == domain 4  score: 3.2 bits;  conditional E-value: 0.13
                  HHHHHHHHTT-HHHHH CS
      ANAPC3   28 llAlclylngqykrAy 43  
                  llA++++++g++++A+
  EEA20937.1 1632 LLAKSYLKQGEWQTAL 1647
                  5788888888888776 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.2     0.057        46      12      26 ..    1309    1323 ..    1308    1330 .. 0.90
   2 ?   -0.5   0.1       1.5   1.2e+03      12      26 ..    1410    1424 ..    1406    1425 .. 0.82
   3 ?    3.9   0.1     0.065        53       6      22 ..    1632    1648 ..    1628    1649 .. 0.89

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.057
                  HHTT-HHHHHHHHHH CS
       TPR_1   12 fklgkydeAleyyek 26  
                   kl++++eAl++y++
  EEA20937.1 1309 EKLQRWEEALAAYKR 1323
                  799**********97 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 1.5
                  HHTT-HHHHHHHHHH CS
       TPR_1   12 fklgkydeAleyyek 26  
                   + ++++eA  y ek
  EEA20937.1 1410 INRNQFEEAAHYIEK 1424
                  5789********998 PP

  == domain 3  score: 3.9 bits;  conditional E-value: 0.065
                  HHHHHHHHTT-HHHHHH CS
       TPR_1    6 nlGnayfklgkydeAle 22  
                   l+  y+k+g+++ Al+
  EEA20937.1 1632 LLAKSYLKQGEWQTALQ 1648
                  6999***********97 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.0    0.0019       1.6       9      51 ..    1310    1349 ..    1308    1350 .. 0.93
   2 ?   -1.2   0.1       4.2   3.4e+03       4      22 ..    1406    1424 ..    1406    1426 .. 0.84
   3 ?   -0.4   0.0       2.3   1.9e+03       3      17 ..    1633    1647 ..    1632    1649 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.0019
      TPR_16    9 ragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrla 51  
                  +++++++A+aa+++  k+d   Pd     +++ +++ ++g+++
  EEA20937.1 1310 KLQRWEEALAAYKRREKQD---PDSFGITMGKMRCLHALGEWK 1349
                  6789***************...******************986 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 4.2
      TPR_16    4 araalragdyddAaaalea 22  
                  a +a++++++++Aa++ e 
  EEA20937.1 1406 AILAINRNQFEEAAHYIEK 1424
                  568999********99875 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 2.3
      TPR_16    3 laraalragdyddAa 17  
                  la+++l++g+++ A+
  EEA20937.1 1633 LAKSYLKQGEWQTAL 1647
                  788999999999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2382 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       716  (0.0399353); expected 358.6 (0.02)
Passed bias filter:                      533  (0.0297284); expected 358.6 (0.02)
Passed Vit filter:                        64  (0.00356964); expected 17.9 (0.001)
Passed Fwd filter:                        23  (0.00128284); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              22  [number of targets reported over threshold]
# CPU time: 1.29u 0.31s 00:00:01.60 Elapsed: 00:00:00.52
# Mc/sec: 13747.10
//
Query:       EEA20938.1  [L=335]
Description: ketoreductase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.4e-16   58.2   0.0    1.2e-15   57.6   0.0    1.2  1  Epimerase        NAD dependent epimerase/dehydratase family
    6.3e-13   48.4   0.0    8.5e-13   47.9   0.0    1.1  1  3Beta_HSD        3-beta hydroxysteroid dehydrogenase/isomeras
    4.2e-10   39.2   0.1      7e-09   35.2   0.1    2.0  1  NAD_binding_4    Male sterility protein
    9.1e-08   31.9   0.0    1.4e-07   31.3   0.0    1.4  1  GDP_Man_Dehyd    GDP-mannose 4,6 dehydratase
    5.9e-07   29.5   0.0    2.1e-06   27.8   0.0    1.8  2  NAD_binding_10   NAD(P)H-binding
     0.0016   18.4   0.0     0.0028   17.6   0.0    1.3  1  KR               KR domain
  ------ inclusion threshold ------
      0.016   14.7   0.1       0.13   11.8   0.0    2.1  2  NmrA             NmrA-like family
      0.023   14.2   0.0      0.043   13.3   0.0    1.6  1  adh_short        short chain dehydrogenase
      0.063   13.7   0.0       0.13   12.7   0.0    1.5  1  Semialdhyde_dh   Semialdehyde dehydrogenase, NAD binding doma
       0.11   12.8   0.0       0.22   11.8   0.0    1.6  1  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma


Domain annotation for each model (and alignments):
>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.6   0.0   6.8e-19   1.2e-15       1     233 [.       4     258 ..       4     264 .. 0.81

  Alignments for each domain:
  == domain 1  score: 57.6 bits;  conditional E-value: 6.8e-19
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC........EEEE--TT-HHHHHHHHHHH.T-SEEEE--S---HHHHHHSHHHHHH. CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl........elveldltdrsalerlfkee.qpdavihlAavggvaassedpadfie. 89 
                 +++tG++Gfi +++++ lle+g ev++  r ++++ + +++           ++  d+ ++ a+++++k+  + d+vih    +  + +++dp + i  
  EEA20938.1   4 VFLTGGSGFIAAHVLNILLEHGFEVVTTVRSQQKGDKILEAYPnlsrdklsYVIVEDIAKEGAFDEVLKSGpAYDYVIHT--ASPFHYNFTDPVKEILn 100
                 578*******************996666666555554444444799**99988999**************99********..56667788998765552 PP

                 HHTHHHHHHHHHHHHH..TCTEEEEEEEGGGGTSCSSSS............BSTCSTTS----SSHHHHHHHHHHHHHHHHHHHH..T-EEEEEEESEE CS
   Epimerase  90 knlqgtlnlleaarka..gvkrllflsSsevYGkdaeqp............keettltgplkpnspYaaaKlageklveayaaqy..glnaiilrlfnl 172
                   ++gt  +l+a++++   vkr++  sS +     ++ p             ee t   + +  + Y  +K+ +ek ++++ ++   ++++ ++++  +
  EEA20938.1 101 PAINGTKGILNAIKTYvpSVKRVVITSSFAAITHAPNHPklydesvwnpvtYEEAT---KDNKFTTYRGSKTFAEKAAWEFVEKEkpNFDVATINPPFV 196
                 7899************99999*******6665533333444433333325556666...66889*****************9998667*********** PP

                 ESTT...S-TTSTTSHHHHHHHHHHTTSSSEEEETTST-EEEEEEHHHHHHHHHHHHHHHTT-S CS
   Epimerase 173 yGpr...ngegevsrvipalirkilegkqevtllgdgtalRdflyveDvaeaillvlehvdagd 233
                 +Gp        e  +   ++i+ +++gk   +  ++ t+ + +++v+Dva a++ ++e  +ag 
  EEA20938.1 197 FGPVigyLNSLESLNTSNQIITDFALGK--KKNDSSPTEHMLWVDVRDVALAHVKAIEVAEAGG 258
                 ****987666668888899********9..5555688999******************977664 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.9   0.0   4.7e-16   8.5e-13       2     230 ..       6     252 ..       5     268 .. 0.76

  Alignments for each domain:
  == domain 1  score: 47.9 bits;  conditional E-value: 4.7e-16
   3Beta_HSD   2 vtGgaGFlGralvkeLvrlee..lkevrvlDlrespelleelskvnvkk...viegDvtdkdkleealeg...vdvvihlaslvdvagkltedeimkvn 92 
                 +tGg+GF+ +++ + L++ +   + +vr+   ++++++le   ++ ++k   vi  D+ ++   +e+l++    d vih+as      ++  +ei +  
  EEA20938.1   6 LTGGSGFIAAHVLNILLEHGFevVTTVRS--QQKGDKILEAYPNLSRDKlsyVIVEDIAKEGAFDEVLKSgpaYDYVIHTASPFHYNFTDPVKEILNPA 102
                 69****************98633555555..6788999999999999999988899************97444699*********9999********** PP

   3Beta_HSD  93 vkGTrnvleacvka..gvrvlvYtSsaevvg.....pnslgeeiln..gdEeleyeslhqdaypesKalaEklvlkaNgrtlknggrlyTcaLRpagiy 182
                 ++GT+ +l+a ++   +v+++v tSs  ++      p  + e + n    Ee + ++    +y  sK  aEk+  +  +   k+  ++    + p  ++
  EEA20938.1 103 INGTKGILNAIKTYvpSVKRVVITSSFAAIThapnhPKLYDESVWNpvTYEEATKDN-KFTTYRGSKTFAEKAAWEFVE---KEKPNFDVATINPPFVF 197
                 **********9874449*************722111234556666522233333333.44689********99888777...7777999999******* PP

   3Beta_HSD 183 Gegdkllvpllkqlaklglal..fkigdeevlsd......rvYvgNvawahilAar 230
                 G+    l ++l+ l  +++++  f +g++++ s+      +v v  va ah+ A  
  EEA20938.1 198 GPVIGYL-NSLESLNTSNQIItdFALGKKKNDSSptehmlWVDVRDVALAHVKAIE 252
                 **87665.445555555554422677777776654444447889999999998865 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.2   0.1   3.9e-12     7e-09       1     219 [.       6     208 ..       6     241 .. 0.71

  Alignments for each domain:
  == domain 1  score: 35.2 bits;  conditional E-value: 3.9e-12
                    EE-TTSHHHHHHHHHHHHHS-.TEEEEEE-SSSHHHHHHHHHHHT-SS-HHHHHHHHHTTTEEEEE--TTSGGGG--HHHHHHHHHH--EEEE--S CS
  NAD_binding_4   1 lTGaTGFLGkvLlekLLrttpevkiyllvRaksgesaeeRleeelekkelfsallkelaerikvveGDlseprlGLseedlqelaeevdviihsaA 96 
                    lTG++GF+++++l+ LL+     +++  vR++++    +++   le ++  s+      +   v++ D++++      +++ +     d +ih a 
     EEA20938.1   6 LTGGSGFIAAHVLNILLEHGF--EVVTTVRSQQK---GDKI---LEAYPNLSRD-----KLSYVIVEDIAKEG---AFDEVLKSGPAYDYVIHTAS 85 
                    8****************9976..8******9866...4555...4555554444.....23457888999997...334444455789*******9 PP

                    ..S-S.STTSSEEHHHHHHHHHHHHHHHTS.SS--.-EEEEEE.GGGTTS-TTT--SSS-H......HHH--EEEETTTCCCHHHHHHHHHHHHHH CS
  NAD_binding_4  97 ..tvnfdepykellrvNveGtrevlelakk.lkklkvllhvST.ayvngeregeveekvyeegekeekldederaklkglpntYeqsKalaEklvr 188
                       +nf++p+ke+l++ ++Gt+ +l+  k+ + + k ++  S+ a+++ + +   + k+y+e   +    + e+a++++  +tY  sK  aEk   
     EEA20938.1  86 pfHYNFTDPVKEILNPAINGTKGILNAIKTyVPSVKRVVITSSfAAITHAPN---HPKLYDESVWN--PVTYEEATKDNKFTTYRGSKTFAEKAAW 176
                    44468999*********************83445577777777544443333...34777655444..444455555566689**********998 PP

                    HHHHHH..---EEEEEE-EEE--SSST---TTS CS
  NAD_binding_4 189 earrrs..glpvvivRpsiitgesktGwingsd 219
                    e  +++  ++ v+ + p+ + g ++ G++n+ +
     EEA20938.1 177 EFVEKEkpNFDVATINPPFVFG-PVIGYLNSLE 208
                    876553116779********99.7777777665 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.3   0.0   7.7e-11   1.4e-07       2     129 ..       6     128 ..       5     178 .. 0.84

  Alignments for each domain:
  == domain 1  score: 31.3 bits;  conditional E-value: 7.7e-11
                    EETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHHHH.T-SEEEE--S---HHHHTTSHH CS
  GDP_Man_Dehyd   2 iTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkgDltDssslerllaev.qpdevynLAAqshVdvsfekPe 96 
                     TG++Gfi +++++ Lle g+ev+ +vr +++ +  +i + +   + + ++   ++  D+  + + +++l++    d v++ A     ++ f++P 
     EEA20938.1   6 LTGGSGFIAAHVLNILLEHGFEVVTTVRSQQKGD--KILEAYP--NLSRDKLSYVIVEDIAKEGAFDEVLKSGpAYDYVIHTASP--FHYNFTDPV 95 
                    6************************999888865..5544453..3333444557778************997689*****9865..568999997 PP

                    H.HHHHHTHHHHHHHHHHHHCT..TTSEEEEEEE CS
  GDP_Man_Dehyd  97 y.taevnvlGtlrLLeairalglekkvrfyqaSt 129
                    +  ++  + Gt  +L+ai+++   + +r++++S+
     EEA20938.1  96 KeILNPAINGTKGILNAIKTYV-PSVKRVVITSS 128
                    615677889***********94.56678888887 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0   1.1e-09   2.1e-06       1     123 [.       8     153 ..       8     175 .. 0.75
   2 ?   -1.2   0.0       0.9   1.6e+03      77     103 ..     241     271 ..     217     288 .. 0.56

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 1.1e-09
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHHCT.TTCE......EEE--TT-CCHHHHHHT...T-SEEEES---TCC.....HHHH... CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpeklaeleae.egle......vvegdvtdvedlaealk...gadaVvsalggggk.....deeg... 77 
                     G++G ++ ++++ ll++ g+ev+  vR+++k +++ ++ ++l+      v++ d+ ++ +  e+lk    +d V+ ++++ +             
      EEA20938.1   8 GGSGFIAAHVLNILLEH-GFEVVTTVRSQQKGDKILEAyPNLSrdklsyVIVEDIAKEGAFDEVLKsgpAYDYVIHTASPFHYnftdpV--Keil 99 
                     9****************.5*********9999865422254442222236667888888888888888889*******66554454442..1336 PP

                     ......HHHHHHHHHH..CT--EEEEEEETTTTSGCGCHHHHHHHHCCHHHHHH CS
  NAD_binding_10  78 ......aknivdaake..agvkRfvlvsaigvgdevpgefgewnkellkaylaa 123
                           +k i++a k+    vkR+v+ s++ +  ++p++ + +++++++++  +
      EEA20938.1 100 npaingTKGILNAIKTyvPSVKRVVITSSFAAITHAPNHPKLYDESVWNPVTYE 153
                     666788*********95558**********999899998887777776666443 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.9
                     H.....HHHHHHHHHHCT--EEEEEEETTTTS CS
  NAD_binding_10  77 g.....aknivdaakeagvkRfvlvsaigvgd 103
                           +++++++a eag kRf +  ++ +++
      EEA20938.1 241 RdvalaHVKAIEVA-EAGGKRFFTAEGFMSNK 271
                     04433344555554.46777777766665554 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   1.6e-06    0.0028       4     144 ..       5     136 ..       3     140 .. 0.85

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 1.6e-06
                 EEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT--H CS
          KR   4 litGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklleemta 102
                 ++tGG G ++ ++ + l+e+g + +v + Rs+++ ++  +   +l++   +  +v+ D++++ a  ++l+    ++p+   vih+A  ++ +      +
  EEA20938.1   5 FLTGGSGFIAAHVLNILLEHGFE-VVTTVRSQQKGDKILEAYPNLSRDKLSYVIVE-DIAKEGAFDEVLK----SGPAYDYVIHTASPFHYN-----FT 92 
                 68*******************86.77888998999999999*****9999988877.9999877666665....5678889****9766555.....57 PP

                 HHHHHHHTTTTHHHHHHHHHTTT..S--SEEEEEEEHHHHH--T CS
          KR 103 edleqvlapKvkGawnLhelled..esldffvlfSSiagllgsa 144
                 + ++++l+p ++G++ + ++++    s++ +v++SS a+++ ++
  EEA20938.1  93 DPVKEILNPAINGTKGILNAIKTyvPSVKRVVITSSFAAITHAP 136
                 8999***********999999998889***********998765 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0     7e-05      0.13       3      34 ..       6      37 ..       4     132 .. 0.86
   2 ?    1.0   0.0      0.15   2.6e+02     171     222 ..     227     278 ..     152     285 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 7e-05
                ESSTTSHHHHHHHHHHHHHT-EEEEEES-S-S CS
        NmrA  3 viGaTGrqGksvvrallkaghkvralvRdtks 34
                 +G++G ++++v ++ll++g++v   vR +++
  EEA20938.1  6 LTGGSGFIAAHVLNILLEHGFEVVTTVRSQQK 37
                68**************************9843 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.15
                 ESS-TTS-EE.-HHHHHHHHHHHHHHHHHHHTTEEEEE-SEEE-HHHHHHHHH CS
        NmrA 171 gpgnpkavll.daeeDiGafvikilkdprklkgkriklagntlsgneivelfe 222
                  +++p + +l ++++D++ + +k+++ ++++ gkr   a+  +s +++v+++ 
  EEA20938.1 227 NDSSPTEHMLwVDVRDVALAHVKAIE-VAEAGGKRFFTAEGFMSNKDLVDAIR 278
                 56677777777889999988888886.56678888888888888888887765 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   2.4e-05     0.043       3      68 ..       4      71 ..       2     138 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 2.4e-05
                EEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT.TSE.EEEEE-TTTSHHHHHHHH CS
   adh_short  3 vlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee.gak.alaiqvDvtdreevealv 68
                v+ tG+s+ I   + + l++ G++vv + rs++k  ++++   ++ ++k  ++i  D++++ + ++++
  EEA20938.1  4 VFLTGGSGFIAAHVLNILLEHGFEVVTTVRSQQKGDKILEAYPNLsRDKlSYVIVEDIAKEGAFDEVL 71
                889*****************************************974443566777888887777665 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   7.2e-05      0.13       1      58 [.       3      60 ..       3      76 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 7.2e-05
                    EEEEETTTSHHHHHHHHHHHCTSSEEEEEEEESTTTTTSBHHHHSG..GGTTTECEBEEE CS
  Semialdhyde_dh  1 kvaivGatGyvGqellrlLeehpevelvvllsssrsaGkklaeavk..aleegkdlkved 58
                    kv + G++G + + +l++L eh  +e+v+ + s++ +G k+ ea++  + ++ + + ved
      EEA20938.1  3 KVFLTGGSGFIAAHVLNILLEHG-FEVVTTVRSQQ-KGDKILEAYPnlSRDKLSYVIVED 60
                    68889****************96.99999777777.**********54444455555555 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   0.00012      0.22       5      80 ..       9      87 ..       4     103 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00012
                     --SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHH...TTTCEEEEE-.-TTTHHHHHHHHHTTS...SEEEE-SSGG CS
  Sacchrp_dh_NADP  5 GaGsvGqavaellarhfdvdaeitvadrskeklealaaka...lgvrfeaial.daenyeavLaallkeg...dlvvnlsppi 80
                     G+G+++  v+  l++h+ +  e++   rs++k ++++++    ++ +++ + + d++++ a  +++lk+g   d v++ + p+
       EEA20938.1  9 GSGFIAAHVLNILLEHG-F--EVVTTVRSQQKGDKILEAYpnlSRDKLSYVIVeDIAKEGA-FDEVLKSGpayDYVIHTASPF 87
                     66**************8.5..7***************988888666666555525555555.999999999999999999888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (335 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       572  (0.0319036); expected 358.6 (0.02)
Passed bias filter:                      520  (0.0290033); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.56u 0.30s 00:00:00.86 Elapsed: 00:00:00.48
# Mc/sec: 2102.09
//
Query:       EEA20939.1  [L=435]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   2.2e-111  373.0   0.2   2.5e-111  372.8   0.2    1.0  1  Mit_ribos_Mrp51  Mitochondrial ribosomal protein subunit


Domain annotation for each model (and alignments):
>> Mit_ribos_Mrp51  Mitochondrial ribosomal protein subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  372.8   0.2  1.4e-115  2.5e-111       1     364 [.       6     396 ..       6     397 .. 0.94

  Alignments for each domain:
  == domain 1  score: 372.8 bits;  conditional E-value: 1.4e-115
  Mit_ribos_Mrp51   1 lsplaaLLRnSRLfslpkplpppa.......lsasdtatlpyPthqaItTpksslargdWGLKrslPlksttskvsspvirvnalDtiehitdf 87 
                      lsp+a+LLRnSRLf+lp+pl+ ++        ++s++atlp+Pt++aI+Tp+++l++gdWGLKr+lP+kst++++s+pvirvnalDt+eh+tdf
       EEA20939.1   6 LSPTANLLRNSRLFALPTPLTTAPrpvtsktVNESASATLPHPTRAAIETPPAALYKGDWGLKRALPAKSTIERSSKPVIRVNALDTFEHVTDF 99 
                      59*******************9999******9999*********************************************************** PP

  Mit_ribos_Mrp51  88 esaadhtltlkkfqElgipl.......kssekeakakkSvFeeeadvt..sekakekedkrwkfkgPllagmtegelseylkkkvrkrrkeFkk 172
                      +sa+dh +tl kfqEl++p+       k++++  ka++S Fe++ d++  se ake+ ++ ++++gP+l g++e ++++yl++ +r+rr+e+ k
       EEA20939.1 100 DSAGDHIMTLTKFQELNLPIslpqvarKNRTDFGKAHESPFEARRDNVstSEGAKERGAQVYRQSGPWLGGQSEIQFQAYLHS-LRRRRPELLK 192
                      *************************999999999*************977888899999***********************9.********** PP

  Mit_ribos_Mrp51 173 fLreklaeektaearraalekge....ealkek....iseeelkeylkklradrqklyklvseFLdlaplkske..aaeekasaelskakr... 253
                       Lre+++++ t e+r++a+++g     ++   +    +++ee+++ylk+lrad++ ++ ++s+ Ldl++l+s    ++  ++++e++ a+    
       EEA20939.1 193 QLREQYENKLTVERRKKAQDEGGleadQT---IepvkVTDEEFQSYLKRLRADKRLAGPELSRLLDLHTLSSDLpsMFIGTDYYEANAANLasv 283
                      **********************9855444...3455********************************9988544477777888877777799* PP

  Mit_ribos_Mrp51 254 ...eqgppkthpsaGLsYlrtgaylenhPlygpqkqktpvpaRvlsprtsatg.eskaklgvGGfvandpssstsaskvsagleaidpdlerga 343
                         +qgpp+thpsaGL Y+r+ga+l nhP ygpq+  +pv+aRvl+++t++++ +++++lgv+G+  +d+++st+  + + gle++dp++++g 
       EEA20939.1 284 dyaSQGPPRTHPSAGLAYTRSGAILYNHPSYGPQQAMRPVEARVLTAKTKKRRyKRRPVLGVAGIAYEDEHDSTED-NIR-GLEYLDPSIPGGG 375
                      ***99**********************************************9988*************99987554.666.9************ PP

  Mit_ribos_Mrp51 344 kipvevkeasvdsdGrirlev 364
                      k++v +k++s++s+G i le+
       EEA20939.1 376 KVWVVPKRVSISSQGTIDLEA 396
                      ******************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (435 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       448  (0.0249875); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 3121.40
//
Query:       EEA20940.1  [L=139]
Description: 40S ribosomal protein S17, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.1e-60  200.5   0.8    7.5e-60  200.2   0.8    1.1  1  Ribosomal_S17e  Ribosomal S17


Domain annotation for each model (and alignments):
>> Ribosomal_S17e  Ribosomal S17
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  200.2   0.8   4.2e-64   7.5e-60       1     118 [.       1     123 [.       1     129 [. 0.93

  Alignments for each domain:
  == domain 1  score: 200.2 bits;  conditional E-value: 4.2e-64
                     XX----HHHHHHHHHHHHS-TTT--S-HHHHHHHHHHHS----SHHHHHHHHHHHHHHHHTTSS--SS---HHHHHHHHHHH------------- CS
  Ribosomal_S17e   1 mgrvrtktvKkaarviiekyyskltndFhtnkkvceevaiipskklrnkiaGyvthlmkriqkgpvrgislklqeeererrdnyvpevsaldqea 95 
                     mgrvrtktvKk+a+viie+yy+klt+dF+tnk++c+e+aii+sk+lrnkiaGy+thlmkriq+gpvrgis+klqeeerer+d+yvpe+sald+++
      EEA20940.1   1 MGRVRTKTVKKSAKVIIERYYPKLTLDFETNKRLCDEIAIIASKRLRNKIAGYTTHLMKRIQRGPVRGISFKLQEEERERKDQYVPEISALDVSQ 95 
                     9******************************************************************************************7665 PP

                     .....----HHHHHHHHHH-X.XXXXXX CS
  Ribosomal_S17e  96 .....ievdkdtkemlkslgfeslsnle 118
                          ++vd dtk++lkslgf+sl+   
      EEA20940.1  96 sesgqLDVDADTKDLLKSLGFDSLKVNV 123
                     55677****************9988333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (139 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       515  (0.0287244); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.31s 00:00:00.73 Elapsed: 00:00:00.46
# Mc/sec: 901.53
//
Query:       EEA20941.1  [L=310]
Description: DUF408 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.9e-22   77.6   0.0    1.5e-21   76.5   0.0    1.6  1  RPAP2_Rtr1       Rtr1/RPAP2 family
     0.0054   17.4   1.5      0.019   15.7   1.5    1.9  1  U3_snoRNA_assoc  U3 snoRNA associated


Domain annotation for each model (and alignments):
>> RPAP2_Rtr1  Rtr1/RPAP2 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.5   0.0   1.6e-25   1.5e-21       3      74 ..      81     162 ..      79     163 .. 0.97

  Alignments for each domain:
  == domain 1  score: 76.5 bits;  conditional E-value: 1.6e-25
                 --HHHHHHHHHHHHCTT--SSTT--S--SS-----------................--TTGGGGT-SSHHHHHHHHHHHHCS CS
  RPAP2_Rtr1   3 lspsdyddvveERniekkCGyplCnnsleedkrqkekyris...........rkakkvvereelekfCSkaCaerslavraqL 74 
                 ++p d+d+++ ERnie++CGy+lC++++++++  + k+ri             +++kvv+re+le++CS++Caer++++r+qL
  EEA20941.1  81 FQPVDFDNLILERNIEGRCGYALCPREHRKED-PNAKFRILwgpkgsgdngrGREMKVVPREKLEMWCSDQCAERAMYLRVQL 162
                 899*************************9999.*************************************************9 PP

>> U3_snoRNA_assoc  U3 snoRNA associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   1.5   2.1e-06     0.019       3      69 ..     179     259 ..     179     271 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 2.1e-06
  U3_snoRNA_assoc   3 Pdeilealee..redeeeaeeekskhin............eepkkarkkkkkekllelkekrpkdvkkGpvsvrVlkssns 69 
                      P e+le++++  +e++++  e++ + ++            + ++++  +++k+  le+ + +p+ +++G v v+V++++ +
       EEA20941.1 179 PLELLEEAQQtrKEATKTNGEQEDRTLTekmknlkvndesSSASASTSEHTKQLALERGDTGPTFRNQGRVDVNVQEKDVD 259
                      8999999999875555555555555555778899999*887777788888888888999******************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (310 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1444  (0.0805399); expected 358.6 (0.02)
Passed bias filter:                      657  (0.0366445); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.42
# Mc/sec: 2204.27
//
Query:       EEA20942.1  [L=1181]
Description: SH3 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.7e-11   43.5   0.1    4.5e-11   42.2   0.1    1.8  1  SH3_1           SH3 domain
    6.4e-09   35.4   0.0    1.3e-08   34.4   0.0    1.5  1  SH3_2           Variant SH3 domain
    8.8e-09   35.1   0.1    1.7e-08   34.2   0.1    1.5  1  SH3_9           Variant SH3 domain
  ------ inclusion threshold ------
      0.017   14.9   1.1      0.017   14.9   1.1    2.5  2  DUF3464         Photosynthesis affected mutant 68
       0.68    9.5   5.2        0.2   11.2   1.6    1.9  2  F-protein       Negative factor, (F-Protein) or Nef
        3.6    5.6  12.0        6.4    4.8  12.0    1.3  1  DNA_pol_phi     DNA polymerase phi


Domain annotation for each model (and alignments):
>> SH3_1  SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.2   0.1   1.5e-14   4.5e-11       1      47 [.       9      58 ..       9      59 .. 0.97

  Alignments for each domain:
  == domain 1  score: 42.2 bits;  conditional E-value: 1.5e-14
                EESSSBEXSSTTBXEBSTTEEEEEEEECSSSEEEEEETTS...TEEEEEE CS
       SH3_1  1 iAlYDYeaeesdELsfkkGDviivleksedgWwkgrlkgt...gkeGliP 47
                +Al+DY+ e++d+L f  G vi+v + ++++W+ g+++++   ++eG++P
  EEA20942.1  9 KALFDYTSEHEDDLHFSIGQVITVTAVEDADWYYGEYNDDagsKQEGIFP 58
                7**************************************9999******* PP

>> SH3_2  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.4   0.0   4.4e-12   1.3e-08       2      55 ..       8      63 ..       7      64 .. 0.90

  Alignments for each domain:
  == domain 1  score: 34.4 bits;  conditional E-value: 4.4e-12
                EEESS-B-SCGCCB--B-TTEEEEEE..EEEECTTEEEEEEC.....CCEEEEEGCGEE CS
       SH3_2  2 vraiedyvgedkseLsfkkGdvikvlslgskdsdgwwegevg.....GrvGlfPsslve 55
                v+a++dy++e ++ L+f  G+vi v+     ++ +w++ge++     ++ G+fP+++ve
  EEA20942.1  8 VKALFDYTSEHEDDLHFSIGQVITVT---AVEDADWYYGEYNddagsKQEGIFPRNFVE 63
                89************************...99999*****99556755556*******97 PP

>> SH3_9  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.2   0.1   5.6e-12   1.7e-08       1      49 []      10      63 ..      10      63 .. 0.89

  Alignments for each domain:
  == domain 1  score: 34.2 bits;  conditional E-value: 5.6e-12
       SH3_9  1 AlypyepreddeLsLqrGDvitvieesedgWlegs.l....tGrtGlvPanyve 49
                Al++y+  ++d L+++ G+vitv   ++ +W++g+ +    + + G +P+n+ve
  EEA20942.1 10 ALFDYTSEHEDDLHFSIGQVITVTAVEDADWYYGEyNddagSKQEGIFPRNFVE 63
                89*********************9666********73565555*********97 PP

>> DUF3464  Photosynthesis affected mutant 68
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   3.9       2.4   7.3e+03      26      40 ..     291     305 ..     255     325 .. 0.42
   2 ?   14.9   1.1   5.8e-06     0.017      11      75 ..     391     457 ..     380     461 .. 0.70

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 2.4
     DUF3464  26 kakkeekekakeeek 40 
                    +e ++k+++++k
  EEA20942.1 291 SRLAEAAQKKEKAKK 305
                 111111111111111 PP

  == domain 2  score: 14.9 bits;  conditional E-value: 5.8e-06
     DUF3464  11 kkkrkkkpkkkkkskkakkeekekakeeekkdkeekeeaaiPevVskRm..irRvalfsGiPlalGl 75 
                 ++  +++p+++k++ +++++++ +++e++ +d+ee+ee+++  +V++Rm   +R+a +sG   ++G+
  EEA20942.1 391 REDADERPRAQKHAVHEQQTDDGDNEEAAAEDDEEEEEEEVDPEVRRRMelRERMAKMSGGMGMMGM 457
                 3444456666666666666666677777888888888899*********444789999997666666 PP

>> F-protein  Negative factor, (F-Protein) or Nef
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.1       2.2   6.6e+03      27      57 ..     279     309 ..     274     321 .. 0.68
   2 ?   11.2   1.6   6.8e-05       0.2      29     100 ..     378     448 ..     360     464 .. 0.71

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 2.2
                 --SS..........S-S.....SSSCCHHHH CS
   F-protein  27 vaalldelegessqsqeesdkeakskslekq 57 
                 +a l++++ +++s+  e+++k++k k+  k+
  EEA20942.1 279 IALLQKQQLEQASRLAEAAQKKEKAKKPPKK 309
                 5566677778888888877777766655444 PP

  == domain 2  score: 11.2 bits;  conditional E-value: 6.8e-05
                 SS..........S-S.....SSSCCHHHHHTT-SS-SSSSSSSS--XXXXXXXXXXXXXXXXXXXXXXXXXX CS
   F-protein  29 alldelegessqsqeesdkeakskslekqkaitgeatrqqnadladleseeedevgvpvrprvplRemtykl 100
                 a   e  +e+s+s e++d+  + ++   ++++t +  +++   + d e+eee+ev   vr+r+ lRe   k+
  EEA20942.1 378 AADTEDAEETSTSREDADERPRAQKHAVHEQQTDDGDNEEA-AAEDDEEEEEEEVDPEVRRRMELRERMAKM 448
                 33345667788888888877777666666555555544444.4467899999**************876665 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8  12.0    0.0021       6.4     628     697 ..     369     449 ..     363     475 .. 0.50

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0021
  DNA_pol_phi 628 renkegqaelfedededeeddeeeeeeddeededse.....eddde......eesdedeededdedvdeid.......elreklaeal 697
                  + n ++ +  +++ed +e+  + e+ ++    ++ +     +          e   ed+e+e++e+v   d       elre++a+  
   EEA20942.1 369 DTNDADYSGAADTEDAEETSTSREDADERPRAQK-HavheqQ---TddgdneEAAAEDDEEEEEEEV---DpevrrrmELRERMAKMS 449
                  4444444444423333333222222222222221.1232221...1112112333333334444444...344577888888887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1216  (0.0678231); expected 358.6 (0.02)
Passed bias filter:                      537  (0.0299515); expected 358.6 (0.02)
Passed Vit filter:                       102  (0.00568911); expected 17.9 (0.001)
Passed Fwd filter:                        29  (0.00161749); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.23u 0.32s 00:00:01.55 Elapsed: 00:00:00.55
# Mc/sec: 6469.75
//
Query:       EEA20943.1  [L=1181]
Description: SH3 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.7e-11   43.5   0.1    4.5e-11   42.2   0.1    1.8  1  SH3_1           SH3 domain
    6.4e-09   35.4   0.0    1.3e-08   34.4   0.0    1.5  1  SH3_2           Variant SH3 domain
    8.8e-09   35.1   0.1    1.7e-08   34.2   0.1    1.5  1  SH3_9           Variant SH3 domain
  ------ inclusion threshold ------
      0.017   14.9   1.1      0.017   14.9   1.1    2.5  2  DUF3464         Photosynthesis affected mutant 68
       0.68    9.5   5.2        0.2   11.2   1.6    1.9  2  F-protein       Negative factor, (F-Protein) or Nef
        3.6    5.6  12.0        6.4    4.8  12.0    1.3  1  DNA_pol_phi     DNA polymerase phi


Domain annotation for each model (and alignments):
>> SH3_1  SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.2   0.1   1.5e-14   4.5e-11       1      47 [.       9      58 ..       9      59 .. 0.97

  Alignments for each domain:
  == domain 1  score: 42.2 bits;  conditional E-value: 1.5e-14
                EESSSBEXSSTTBXEBSTTEEEEEEEECSSSEEEEEETTS...TEEEEEE CS
       SH3_1  1 iAlYDYeaeesdELsfkkGDviivleksedgWwkgrlkgt...gkeGliP 47
                +Al+DY+ e++d+L f  G vi+v + ++++W+ g+++++   ++eG++P
  EEA20943.1  9 KALFDYTSEHEDDLHFSIGQVITVTAVEDADWYYGEYNDDagsKQEGIFP 58
                7**************************************9999******* PP

>> SH3_2  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.4   0.0   4.4e-12   1.3e-08       2      55 ..       8      63 ..       7      64 .. 0.90

  Alignments for each domain:
  == domain 1  score: 34.4 bits;  conditional E-value: 4.4e-12
                EEESS-B-SCGCCB--B-TTEEEEEE..EEEECTTEEEEEEC.....CCEEEEEGCGEE CS
       SH3_2  2 vraiedyvgedkseLsfkkGdvikvlslgskdsdgwwegevg.....GrvGlfPsslve 55
                v+a++dy++e ++ L+f  G+vi v+     ++ +w++ge++     ++ G+fP+++ve
  EEA20943.1  8 VKALFDYTSEHEDDLHFSIGQVITVT---AVEDADWYYGEYNddagsKQEGIFPRNFVE 63
                89************************...99999*****99556755556*******97 PP

>> SH3_9  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.2   0.1   5.6e-12   1.7e-08       1      49 []      10      63 ..      10      63 .. 0.89

  Alignments for each domain:
  == domain 1  score: 34.2 bits;  conditional E-value: 5.6e-12
       SH3_9  1 AlypyepreddeLsLqrGDvitvieesedgWlegs.l....tGrtGlvPanyve 49
                Al++y+  ++d L+++ G+vitv   ++ +W++g+ +    + + G +P+n+ve
  EEA20943.1 10 ALFDYTSEHEDDLHFSIGQVITVTAVEDADWYYGEyNddagSKQEGIFPRNFVE 63
                89*********************9666********73565555*********97 PP

>> DUF3464  Photosynthesis affected mutant 68
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   3.9       2.4   7.3e+03      26      40 ..     291     305 ..     255     325 .. 0.42
   2 ?   14.9   1.1   5.8e-06     0.017      11      75 ..     391     457 ..     380     461 .. 0.70

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 2.4
     DUF3464  26 kakkeekekakeeek 40 
                    +e ++k+++++k
  EEA20943.1 291 SRLAEAAQKKEKAKK 305
                 111111111111111 PP

  == domain 2  score: 14.9 bits;  conditional E-value: 5.8e-06
     DUF3464  11 kkkrkkkpkkkkkskkakkeekekakeeekkdkeekeeaaiPevVskRm..irRvalfsGiPlalGl 75 
                 ++  +++p+++k++ +++++++ +++e++ +d+ee+ee+++  +V++Rm   +R+a +sG   ++G+
  EEA20943.1 391 REDADERPRAQKHAVHEQQTDDGDNEEAAAEDDEEEEEEEVDPEVRRRMelRERMAKMSGGMGMMGM 457
                 3444456666666666666666677777888888888899*********444789999997666666 PP

>> F-protein  Negative factor, (F-Protein) or Nef
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.1       2.2   6.6e+03      27      57 ..     279     309 ..     274     321 .. 0.68
   2 ?   11.2   1.6   6.8e-05       0.2      29     100 ..     378     448 ..     360     464 .. 0.71

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 2.2
                 --SS..........S-S.....SSSCCHHHH CS
   F-protein  27 vaalldelegessqsqeesdkeakskslekq 57 
                 +a l++++ +++s+  e+++k++k k+  k+
  EEA20943.1 279 IALLQKQQLEQASRLAEAAQKKEKAKKPPKK 309
                 5566677778888888877777766655444 PP

  == domain 2  score: 11.2 bits;  conditional E-value: 6.8e-05
                 SS..........S-S.....SSSCCHHHHHTT-SS-SSSSSSSS--XXXXXXXXXXXXXXXXXXXXXXXXXX CS
   F-protein  29 alldelegessqsqeesdkeakskslekqkaitgeatrqqnadladleseeedevgvpvrprvplRemtykl 100
                 a   e  +e+s+s e++d+  + ++   ++++t +  +++   + d e+eee+ev   vr+r+ lRe   k+
  EEA20943.1 378 AADTEDAEETSTSREDADERPRAQKHAVHEQQTDDGDNEEA-AAEDDEEEEEEEVDPEVRRRMELRERMAKM 448
                 33345667788888888877777666666555555544444.4467899999**************876665 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8  12.0    0.0021       6.4     628     697 ..     369     449 ..     363     475 .. 0.50

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0021
  DNA_pol_phi 628 renkegqaelfedededeeddeeeeeeddeededse.....eddde......eesdedeededdedvdeid.......elreklaeal 697
                  + n ++ +  +++ed +e+  + e+ ++    ++ +     +          e   ed+e+e++e+v   d       elre++a+  
   EEA20943.1 369 DTNDADYSGAADTEDAEETSTSREDADERPRAQK-HavheqQ---TddgdneEAAAEDDEEEEEEEV---DpevrrrmELRERMAKMS 449
                  4444444444423333333222222222222221.1232221...1112112333333334444444...344577888888887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1216  (0.0678231); expected 358.6 (0.02)
Passed bias filter:                      537  (0.0299515); expected 358.6 (0.02)
Passed Vit filter:                       102  (0.00568911); expected 17.9 (0.001)
Passed Fwd filter:                        29  (0.00161749); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.33u 0.34s 00:00:01.67 Elapsed: 00:00:00.59
# Mc/sec: 6069.24
//
Query:       EEA20944.1  [L=563]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.6e-52  177.1  22.5    4.6e-52  177.1  22.5    2.0  2  MFS_1          Major Facilitator Superfamily
    9.2e-08   31.4  11.4    9.2e-08   31.4  11.4    2.3  2  Sugar_tr       Sugar (and other) transporter
  ------ inclusion threshold ------
       0.23   11.1   5.8       0.65    9.6   5.8    1.8  1  CPP1-like      Protein CHAPERONE-LIKE PROTEIN OF POR1-like
        3.2    5.9  11.5       0.26    9.5   3.1    2.8  3  OATP           Organic Anion Transporter Polypeptide (OATP) f


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  177.1  22.5     1e-55   4.6e-52       2     350 ..     105     509 ..     104     512 .. 0.82
   2 ?    1.9   1.2     0.019        87     132     183 ..     507     555 ..     505     560 .. 0.78

  Alignments for each domain:
  == domain 1  score: 177.1 bits;  conditional E-value: 1e-55
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlga 99 
                 ++a+f+s +++ i++pa+  +la+dl++s s i+l +t y++++++a +++G ++d+ Grr+ +++++++++ + + l++ ++++ +l+vlr++q++g+
  EEA20944.1 105 SCAGFFSPISSQIYFPAMN-TLAKDLNVSISLINLTMTSYMIFQGIAPVFIGDFADNAGRRPAYFICFIIYLGANVGLAL-QNSYaALFVLRCMQSAGS 201
                 699****************.******************************************************666666.88888************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 ++ ++++a +iad+++  erg+++g+++ag+ lG++lgp++ggll+++lgWr++f++l i+++ +++ f+l++pe+ ++   + +++            
  EEA20944.1 202 STTIALSAGVIADIASVAERGSYMGFVTAGSLLGPALGPVIGGLLSQYLGWRSIFWFLFIIAAAWLIQFILFYPETGRKIVSNGSIPPPkwnmslisyi 300
                 *******************************************************************999***88888888888888878888888888 PP

       MFS_1 189 .......................kgtgpaplvp.awkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailall 263
                                        k  +p pl + a+ + +   vl  l++ +++f+ ++  +++ + ly  e +gl+  l++gl +  +++++a +a+ 
  EEA20944.1 301 ksrkevseedrlaaestlpcaprKLSFPNPLPTlAIVLQKDTAVL--LITNSIFFAGFYDVAVAITSLY-SEIYGLN-DLEIGLCYLPFGAGSALAAFA 395
                 888888777778555555444443333333333223333333344..7777777766777799999999.*******.599999999999999999*** PP

       MFS_1 264 agrlsdr.......................lgr.rrrlllallllllaalglallavtssavllll....vlvliGfglgfvfpsllalasdlappeea 334
                  g+l+d                        ++  + rl +a++l+l a ++++++++  ++ ++++    + +++Gf+l   f ++ +l+ dl+p ++a
  EEA20944.1 396 NGKLLDVnyrriatqlglpvqrnrhtdlknFPIeKARLQIAFPLILGAIALIIVFGWVLDYGVHVAaptiITFFMGFCLTGSFNTVSTLLIDLYP-NKA 493
                 *****99999999998888776666665554445666666666666666666666666777777775655666688877777************8.99* PP

       MFS_1 335 gtasglfntagslgga 350
                 +ta++  n++++l ga
  EEA20944.1 494 ATATAGSNITRCLLGA 509
                 ************8776 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.019
       MFS_1 132 lGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrks 183
                 lGa  ++++ ++l+ + g  +++ ++a+v+l    l  l+++ ++ +++r++
  EEA20944.1 507 LGAGATAVIEPMLT-AMGAGWCYTFIALVMLATTPL--LFILINYGPKWREE 555
                 67778888888888.777888888899999988777..88888888888775 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.4  11.4   2.1e-11   9.2e-08      20     202 ..     108     285 ..     101     291 .. 0.88
   2 ?   -0.1  12.0     0.073   3.3e+02     329     436 ..     444     545 ..     433     547 .. 0.66

  Alignments for each domain:
  == domain 1  score: 31.4 bits;  conditional E-value: 2.1e-11
                 GGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHH CS
    Sugar_tr  20 gafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGl 118
                 g+f+ +++++++  +++  ++ + s +l+ l++ ++++ + i  +f+g ++d  GR++++ i+ ++++ ++v  a+ +   s+ +l+v R     g  +
  EEA20944.1 108 GFFSPISSQIYFPAMNTLAKDLNVSISLINLTMTSYMIFQGIAPVFIGDFADNAGRRPAYFICFIIYLGANVGLALQN---SYAALFVLRCMQSAGSST 203
                 45555556666666666666666677899*************************************************...****************** PP

                 HHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHH.HHHHGGGS---HHHHHHTT CS
    Sugar_tr 119 asvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpall.llilllflPESPrylvekg 202
                 + +l+   i+ iA  + Rg  +++   +  +G  ++ ++g  l+++ +   wr  +++ +++a + l+ ++lf PE+ r  v++g
  EEA20944.1 204 TIALSAGVIADIASVAERGSYMGFVTAGSLLGPALGPVIGGLLSQYLG---WRSIFWFLFIIAAAwLIQFILFYPETGRKIVSNG 285
                 **********************99999999999999999999999988...**999999988876256688******98777766 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.073
                 HHHHHHH..HHHHTTSS.....CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHH CS
    Sugar_tr 329 icfvilgivalllvaks..kaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfagl 425
                 i+++    +++ +v      +a+  +i+f++ f  + + ++++v   l+ +l+p++  ++++    +   l   +++++ p++t a+g+g+++ + a +
  EEA20944.1 444 IALI----IVFGWVLDYgvHVAAPTIITFFMGF--CLTGSFNTVS-TLLIDLYPNKAATATAGSNITRCLLGAGATAVIEPMLT-AMGAGWCYTFIALV 534
                 2222....3333333321223455555555555..4443455555.7889******9998888888888888888888877666.6666********** PP

                 HHHHHHHHHHH CS
    Sugar_tr 426 avlfiifvfff 436
                 +++++   f+ 
  EEA20944.1 535 MLATTPLLFIL 545
                 ***99988875 PP

>> CPP1-like  Protein CHAPERONE-LIKE PROTEIN OF POR1-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   5.8   0.00015      0.65     103     169 ..     187     253 ..     181     274 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00015
   CPP1-like 103 flvlavltlvapaesvpalllalglgasiyflnrKekklgravlltlvgLvvGlllGsllasllqvd 169
                 +++l vl  +++a s+++++l+ g++a i ++ ++   +g   + +l+g ++G ++G+ll+++l   
  EEA20944.1 187 YAALFVLRCMQSAGSSTTIALSAGVIADIASVAERGSYMGFVTAGSLLGPALGPVIGGLLSQYLGWR 253
                 899***********************************************************99544 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.3     0.017        74       3      73 ..     101     172 ..      99     184 .. 0.80
   2 ?    9.5   3.1   5.9e-05      0.26     134     226 ..     189     267 ..     177     362 .. 0.73
   3 ?   -3.6   0.0      0.56   2.5e+03     214     240 ..     467     493 ..     463     500 .. 0.78

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.017
                 xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxx RF
        OATP   3 lvllsllglvq.amvsgyfkstittiEkrFklpsstsgliassneignillilfvsYfggr.ghrPrwigiga 73 
                 +++ s++g++  + + +yf  +++t+ k  + + s + l ++s+ i + ++ +f++ f+++ g+rP +  + +
  EEA20944.1 101 VIAASCAGFFSpISSQIYFP-AMNTLAKDLNVSISLINLTMTSYMIFQGIAPVFIGDFADNaGRRPAYFICFI 172
                 67788899999566666665.6799*******************************99988688887655444 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 5.9e-05
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 134 lfflaqlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllklyvdidseisltpkdprWvgaWWlgflilgvll 226
                  +f+  +++ +G+++ ++l    i D ++  +   y+g+++a ++lGpalG ++G+ll + y               W   +W  f+i+++ l
  EEA20944.1 189 ALFVLRCMQSAGSSTTIALSAGVIADIASVAERGSYMGFVTAGSLLGPALGPVIGGLLSQ-YL-------------GWRSIFWFLFIIAAAWL 267
                 56666889999*********************************************7766.53.............35556666666555544 PP

  == domain 3  score: -3.6 bits;  conditional E-value: 0.56
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 214 aWWlgflilgvllllaaiplffFPkel 240
                  +++gf ++g +  ++ +++ ++P + 
  EEA20944.1 467 TFFMGFCLTGSFNTVSTLLIDLYPNKA 493
                 568899999999999999988888874 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (563 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       681  (0.0379832); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.32s 00:00:00.95 Elapsed: 00:00:00.46
# Mc/sec: 3675.92
//
Query:       EEA20945.1  [L=181]
Description: ER membrane DUF1077 domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-49  165.8   3.6    4.2e-49  165.5   3.6    1.1  1  DUF1077   Protein of unknown function (DUF1077)


Domain annotation for each model (and alignments):
>> DUF1077  Protein of unknown function (DUF1077)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  165.5   3.6   2.3e-53   4.2e-49       5     117 ..      56     168 ..      52     169 .. 0.97

  Alignments for each domain:
  == domain 1  score: 165.5 bits;  conditional E-value: 2.3e-53
     DUF1077   5 ekeelkakkaweialapakslpmnlfmlYmsGnslqifsimmvlmllvnpikallsvnkaFkkleseksksklllqklvyvllqllllalglyklnsmG 103
                 e+++lk kkawe+alap k++pmn++m+YmsGnslqifsimmv+ml++ pi+ l+++n++F k+e+e++++k++  k+vyvl+ql+ll++g++k+n+mG
  EEA20945.1  56 ETDTLKLKKAWEVALAPSKQIPMNAIMMYMSGNSLQIFSIMMVFMLFKGPIQGLIATNAQFVKFETESNRTKIWGCKAVYVLMQLVLLGMGVWKVNAMG 154
                 6899*********************************************************************************************** PP

     DUF1077 104 LLPttssDwlafee 117
                 LLPtt+sDwla+e+
  EEA20945.1 155 LLPTTRSDWLAWES 168
                 ************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       472  (0.0263261); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.25s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1337.38
//
Query:       EEA20946.1  [L=718]
Description: AP-2 adaptor complex subunit beta, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   2.7e-115  385.9   6.3   3.5e-115  385.5   6.3    1.0  1  Adaptin_N        Adaptin N terminal region
    1.8e-56  190.7   5.0    3.5e-55  186.5   0.6    3.3  3  Cnd1             non-SMC mitotic condensation complex subunit
    4.6e-13   49.4   4.1     0.0018   18.6   0.0    4.9  6  HEAT_2           HEAT repeats
    4.5e-09   35.8   5.0       0.11   12.8   0.0    5.5  7  HEAT             HEAT repeat
     0.0001   22.3   0.0        2.3    8.3   0.0    4.4  4  Atx10homo_assoc  Spinocerebellar ataxia type 10 protein domai
     0.0027   17.7   1.3        1.3    9.1   0.0    4.6  4  Arm              Armadillo/beta-catenin-like repeat
  ------ inclusion threshold ------
      0.018   15.6   4.5         39    4.9   0.0    5.6  6  HEAT_EZ          HEAT-like repeat
      0.025   14.4   1.8        1.9    8.2   0.1    3.0  3  TIP120           TATA-binding protein interacting (TIP20)
      0.035   13.9   0.0        0.9    9.3   0.0    2.3  2  T_hemolysin      Thermostable hemolysin


Domain annotation for each model (and alignments):
>> Adaptin_N  Adaptin N terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  385.5   6.3  1.8e-118  3.5e-115       9     522 ..      19     537 ..      13     539 .. 0.94

  Alignments for each domain:
  == domain 1  score: 385.5 bits;  conditional E-value: 1.8e-118
                 HHHHCCSSS...-SCHHHHHHHHHHHHHHHCT-.--GHHHHHHHCCCCSS-CHHHHHHHHHHHHHCTTSCCHHCCCCHHHHHHCCSSSHHHHHHHHHHH CS
   Adaptin_N   9 laeilnsnk...dddekkkeavkkliylialGe.dvsflffevvklvaskdfelKrlvYlylellaeesedlalLvtnslqkDlkdpnqlirglALrvL 103
                 l++ lns     ++++ kk a+kk+++ ++ ++ d+  lf++++ +++   +e+K++++lyl+++a  ++++al +   l  D+ d n+l+r+lALr++
  EEA20946.1  19 LRQELNSGGkkdKNHSAKKIALKKIVANMTMSNnDMVGLFPDIIACMTIPSLEIKKMCFLYLVNYARAKPEIALKALPILVDDMDDHNPLVRALALRTI 117
                 34444443366678889999*****987765555***************************************************************** PP

                 CCC--CCCHHHHHHHHHHHHT-SSHHHHHHHHHHHHHCCCCCHHCCCCC.HHHHHHHCTT-SSHHHHHHHHHHHHHH.HCCCCCCCHHHHHHHCCHHHH CS
   Adaptin_N 104 ssirvpelaedlapaikkllkdrspyvrkkAalailklykkdpdllrkq.lveeikellsdkdpgvvlaAvalleei.kkndrlllkllpklvrrLcnl 200
                 s i v+e +e+ ++ +k l++d +pyvrk+Aa +++kly+  ++ ++   l++++ + l+d++p vv++++a+l  i ++++ + l++    +++   +
  EEA20946.1 118 SYIHVREFVEATVQPVKHLMVDVDPYVRKTAAFCVAKLYDHHKKMVESSdLIDRLNKMLKDENPTVVSSVLAALVDIwERSESISLTIDYASASKVVSV 216
                 *****************************************************************************8888888667777788899999 PP

                 HHCS-HHHHHHHHHHHCC---SSHHHH..HHHHHHHCGGCGCSSCHHHHHHHHHCCHCCCCST.......HHHCCHHCHHHHHHSSCCTCHHHHHCHHH CS
   Adaptin_N 201 lteldpwlqvkiiklltrlarqepeerskkellesllnllqssnnaVlletvnlivelapkne.......livlavnaLvrllsskdenlryvaLrtll 292
                 l ++++w+q++i++ l ++++++  e+   +l e++ ++l++sn aV+l ++++i +l++  +       l +++   Lv+lls+++e ++y+aLr+  
  EEA20946.1 217 LADCSEWGQTYILESLMAYVPRDSGEA--LLLAERISPRLSHSNSAVVLTSIRVILYLMNYISdekqvtaLSKKLSPPLVTLLSKPPE-VQYLALRNAI 312
                 9**************************..99*************************99999888999**999****************.********** PP

                 HHHHHXXTTTTTTTCCCCSXXTTSXHHHHHHHHHHHCCCXXTTTHHHHHHHHHHHTTSSXXHHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHTTXXH CS
   Adaptin_N 293 kivkkepkavqhldlkifllktdddvsirlkaldlllklvdesNvkeivkeLkkyvkevadedfksklvkaIgrlaekfatdaewvldvllellslsge 391
                  i++k+ ++v ++d+++f++k++d+++++ ++l+l + l++++N+  ++ eL +y++e+ d  f++k+v+aIg+la+k+++ a++++d+llel   +  
  EEA20946.1 313 LILQKR-PEVLRNDIRVFFCKYNDPIYVKVTKLELIFMLASKENIGVVLAELREYASEI-DVHFVRKAVRAIGKLAIKIESAARQCIDTLLELVHAKVP 409
                 ******.9************************************************999.999************************************ PP

                 HHHHHHHHHHHHHHHHSTTTSTTCHHHHCCTCCGXXSHHHHHHHHHHHHHTTTTXTT...HHHHHHCTTTTTTTSXHHHHHHHHHHHHHHHHCXGCC.T CS
   Adaptin_N 392 svkdeivevirdliqkvpelheeiiekLaellekieseearaaaiWllGeygelvsntesasdllrslaekfvlesekvklqiltalvKlyltspdket 490
                 ++++e+ +vir++++k+p++ e ii  +++ +++++++ea+aa+iW++G+y+++++n      ll+  +  f++e+ +v+l++lta vKl+ + p+k +
  EEA20946.1 410 YIVQEATVVIRNIFRKYPNQYEGIIGAVIQNIDELDEPEAKAAIIWIIGQYADRIEN---SDGLLQDYLATFHDEPIEVQLALLTATVKLFIQRPTKGQ 505
                 *********************************************************...***********************************7655 PP

                 HXHHHHHHHHHHH..XXSHHHHHHHHHHHHHHCC CS
   Adaptin_N 491 qekliqlvlslat..ssdlevrdRaveylqllss 522
                   +l+  vl+ +t  ++d ++rdR ++y++lls+
  EEA20946.1 506 --QLVPEVLKWCTedTDDPDLRDRGYMYWRLLST 537
                 ..555555555555988**************987 PP

>> Cnd1  non-SMC mitotic condensation complex subunit 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.1       1.2   2.5e+03      82     105 ..      43      66 ..      21     103 .. 0.52
   2 !  186.5   0.6   1.8e-58   3.5e-55       1     162 []     108     271 ..     108     271 .. 0.98
   3 ?    4.5   0.0     0.016        33      40     109 ..     377     445 ..     357     520 .. 0.78

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 1.2
        Cnd1  82 lteiseksenaiynllpdiiskls 105
                 +    ++s+n ++ l+pdii  + 
  EEA20946.1  43 IVANMTMSNNDMVGLFPDIIACMT 66 
                 222223344555555555554444 PP

  == domain 2  score: 186.5 bits;  conditional E-value: 1.8e-58
        Cnd1   1 liRalairtlgcirvpnlveylvepLrkrLkDedpyVRktaaivvakL..ilndmvkekgflselaklleDenprVvanalaalteiseksenaiynll 97 
                 l+Rala+rt+++i+v+++ve++v+p+++ + D dpyVRktaa++vakL  ++++mv++++++++l+k+l+Denp+Vv+++laal +i+e+se++ +++ 
  EEA20946.1 108 LVRALALRTISYIHVREFVEATVQPVKHLMVDVDPYVRKTAAFCVAKLydHHKKMVESSDLIDRLNKMLKDENPTVVSSVLAALVDIWERSESISLTID 206
                 79**********************************************777778********************************************* PP

        Cnd1  98 pdiisklsdalnecsewgqitilefLlsyipkdkqeaeslveklcprlqhansavvlaaikviLs 162
                   ++sk+++ l +csewgq++ile+L+ y+p+d+ ea  l+e++ prl+h+nsavvl++i+viL+
  EEA20946.1 207 YASASKVVSVLADCSEWGQTYILESLMAYVPRDSGEALLLAERISPRLSHSNSAVVLTSIRVILY 271
                 ***************************************************************97 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.016
        Cnd1  40 taaivvakL.ilndmvkekgflselaklleDenprVvanalaalteiseksenaiynllpdiisklsdaln 109
                  a+ ++ kL i+ +    ++ +++l++l++ + p +v+ a  ++ +i +k +n+   +   +i+++  +l+
  EEA20946.1 377 KAVRAIGKLaIKIESA-ARQCIDTLLELVHAKVPYIVQEATVVIRNIFRKYPNQYEGIIGAVIQNID-ELD 445
                 4777777885554444.46679999999999999999999999999999987877777777777776.333 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0   9.2e-07    0.0018      31      84 ..      93     149 ..      80     150 .. 0.79
   2 !   18.5   0.0   9.8e-07     0.002      10      59 ..     138     195 ..     129     223 .. 0.78
   3 ?   -3.0   0.0         5     1e+04      39      68 ..     253     286 ..     247     302 .. 0.57
   4 ?   -3.2   0.0       5.7   1.1e+04       2      22 ..     291     309 ..     289     318 .. 0.73
   5 !   10.6   0.1   0.00029      0.57      19      83 ..     345     416 ..     339     419 .. 0.77
   6 !    7.1   0.0    0.0035       6.9      11      77 ..     444     521 ..     435     528 .. 0.70

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 9.2e-07
      HEAT_2  31 ealpaLvellededpavRraaaeaLgaig....dpealpaLkellddddddvvReaAa 84 
                 +alp+Lv+ ++d++p vR+ a ++++ i      +++++  k+l+ d  d++vR  Aa
  EEA20946.1  93 KALPILVDDMDDHNPLVRALALRTISYIHvrefVEATVQPVKHLMVD-VDPYVRKTAA 149
                 789999999999***********999998443348899999999975.6666666554 PP

  == domain 2  score: 18.5 bits;  conditional E-value: 9.8e-07
      HEAT_2  10 ndpdpevrraairaLg.....rignp......ealpaLvellededpavRraaaeaLgaig 59 
                  d dp+vr++a+ + +         +      ++++ L ++l+de+p v   +  aL+ i 
  EEA20946.1 138 VDVDPYVRKTAAFCVAklydhH---KkmvessDLIDRLNKMLKDENPTVVSSVLAALVDIW 195
                 699*************765540...144555599***********************9883 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 5
      HEAT_2  39 llededpavRraaaeaL....gaigdpealpaLk 68 
                  l+++++av  + ++ +      i d++ + aL 
  EEA20946.1 253 RLSHSNSAVVLTSIRVIlylmNYISDEKQVTALS 286
                 5666666666666654312122334454444444 PP

  == domain 4  score: -3.2 bits;  conditional E-value: 5.7
      HEAT_2   2 daLlqalendpdpevrraair 22 
                 ++L+ +l  ++ pev++ a+r
  EEA20946.1 291 PPLVTLL--SKPPEVQYLALR 309
                 5677777..466788877776 PP

  == domain 5  score: 10.6 bits;  conditional E-value: 0.00029
      HEAT_2  19 aairaLgrign.pealpaLvellededpavRraaaeaLgaig......dpealpaLkellddddddvvReaA 83 
                 + i  L+++ n   +l+ L+e+++  d +  r a++a+g+++        + ++ L+el++ +  ++v+ea+
  EEA20946.1 345 ELIFMLASKENiGVVLAELREYASEIDVHFVRKAVRAIGKLAikiesaARQCIDTLLELVHAKVPYIVQEAT 416
                 666677766552456999*********************87544543346679*******999999999986 PP

  == domain 6  score: 7.1 bits;  conditional E-value: 0.0035
      HEAT_2  11 dpdpevrraairaLgrignp..ealpaLvell...ededpavRraaaeaLgai......gdpealpaLkelldddddd 77 
                   +pe ++a+i+ +g+++++   +  +L ++l    de  +v+ a  +a +++      + ++ +p  ++++++d+dd
  EEA20946.1 444 LDEPEAKAAIIWIIGQYADRieNSDGLLQDYLatfHDEPIEVQLALLTATVKLfiqrptKGQQLVPEVLKWCTEDTDD 521
                 468999*********88876545555666666522445569*********9887776664577787777777777664 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.3   0.0    0.0016       3.2       2      25 ..      95     118 ..      94     121 .. 0.90
   2 !   12.2   0.0   8.8e-05      0.18       6      30 ..     134     158 ..     130     159 .. 0.85
   3 !   12.8   0.0   5.7e-05      0.11       1      29 [.     168     196 ..     168     198 .. 0.91
   4 ?   -3.7   0.0         9   1.8e+04       8      23 ..     253     268 ..     250     273 .. 0.76
   5 ?   -2.6   0.0       4.9   9.7e+03      19      28 ..     377     386 ..     375     387 .. 0.83
   6 ?   -3.7   0.0         9   1.8e+04       3      18 ..     398     414 ..     397     417 .. 0.70
   7 ?   -1.4   0.1         2     4e+03       1      13 [.     507     521 ..     507     526 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.0016
                 HHHHHHHHT-SSHHHHHHHHHHHH CS
        HEAT   2 lPlllkllsDpspeVReaAakaLg 25 
                 lP+l+  + D +p VR+ A++++ 
  EEA20946.1  95 LPILVDDMDDHNPLVRALALRTIS 118
                 89999999************9986 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 8.8e-05
                 HHHHT-SSHHHHHHHHHHHHHHHHC CS
        HEAT   6 lkllsDpspeVReaAakaLgalaev 30 
                  +l+ D +p VR++Aa ++++l+ +
  EEA20946.1 134 KHLMVDVDPYVRKTAAFCVAKLYDH 158
                 567789***************9887 PP

  == domain 3  score: 12.8 bits;  conditional E-value: 5.7e-05
                 HHHHHHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgalae 29 
                 l++ l k+l+D++p V ++++ aL+++ e
  EEA20946.1 168 LIDRLNKMLKDENPTVVSSVLAALVDIWE 196
                 677899********************987 PP

  == domain 4  score: -3.7 bits;  conditional E-value: 9
                 HHT-SSHHHHHHHHHH CS
        HEAT   8 llsDpspeVReaAaka 23 
                  ls++++ V  ++++ 
  EEA20946.1 253 RLSHSNSAVVLTSIRV 268
                 5889999998877765 PP

  == domain 5  score: -2.6 bits;  conditional E-value: 4.9
                 HHHHHHHHHH CS
        HEAT  19 aAakaLgala 28 
                  A++a+g+la
  EEA20946.1 377 KAVRAIGKLA 386
                 5999999987 PP

  == domain 6  score: -3.7 bits;  conditional E-value: 9
                 HHHHHHHT-SSHH.HHH CS
        HEAT   3 PlllkllsDpspe.VRe 18 
                 ++ll+l + + p  V e
  EEA20946.1 398 DTLLELVHAKVPYiVQE 414
                 67899999999883344 PP

  == domain 7  score: -1.4 bits;  conditional E-value: 2
                 HHHHHHHHH.T-.SS CS
        HEAT   1 llPlllkll.sD.ps 13 
                 l+P +lk++ +D ++
  EEA20946.1 507 LVPEVLKWCtEDtDD 521
                 7899****9899444 PP

>> Atx10homo_assoc  Spinocerebellar ataxia type 10 protein domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.31   6.2e+02      38      54 ..     102     118 ..      91     128 .. 0.84
   2 ?    2.6   0.0     0.067   1.3e+02      40      62 ..     139     161 ..     133     191 .. 0.78
   3 ?    4.2   0.0     0.022        43      39      61 ..     405     427 ..     376     442 .. 0.85
   4 !    8.3   0.0    0.0012       2.3      25      87 ..     504     566 ..     490     576 .. 0.87

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.31
  Atx10homo_assoc  38 iDdnnPfirewailair 54 
                      +Dd+nP++r  a+ +i 
       EEA20946.1 102 MDDHNPLVRALALRTIS 118
                      8********99988775 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.067
  Atx10homo_assoc  40 dnnPfirewailairnLlegnee 62 
                      d +P++r+ a +++ +L ++ ++
       EEA20946.1 139 DVDPYVRKTAAFCVAKLYDHHKK 161
                      568************99987653 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.022
  Atx10homo_assoc  39 DdnnPfirewailairnLlegne 61 
                      +++ P+i + a++ irn+  +++
       EEA20946.1 405 HAKVPYIVQEATVVIRNIFRKYP 427
                      5678**************98765 PP

  == domain 4  score: 8.3 bits;  conditional E-value: 0.0012
  Atx10homo_assoc  25 eldgleliLsqcniDdnnPfirewailairnLlegneenqelvaeLeakgvvdeevLeelgle 87 
                       ++ ++ +L+ c  D ++P +r+++ +  r L  + ++++e+v   ++  ++++e+Le + le
       EEA20946.1 504 GQQLVPEVLKWCTEDTDDPDLRDRGYMYWRLLSTDPAAAREVVMGEKPPITAESEKLEPNTLE 566
                      5667999************************************99999999999998876655 PP

>> Arm  Armadillo/beta-catenin-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.35   6.9e+02      12      39 ..      93     120 ..      89     120 .. 0.88
   2 ?    0.7   0.0       0.3   5.9e+02      11      36 ..     166     191 ..     157     194 .. 0.81
   3 ?    0.8   0.1      0.28   5.6e+02      15      26 ..     291     301 ..     287     308 .. 0.78
   4 !    9.1   0.0   0.00067       1.3      13      40 ..     396     423 ..     391     424 .. 0.92

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.35
                 THHHHHHHHTTTSSHHHHHHHHHHHHHH CS
         Arm  12 GavppLvrLLssedeevqeeAawALsNL 39 
                  a+p+Lv+ +++ ++ v+  A++++s++
  EEA20946.1  93 KALPILVDDMDDHNPLVRALALRTISYI 120
                 6899999999999999999999999997 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.3
                 TTHHHHHHHHTTTSSHHHHHHHHHHH CS
         Arm  11 aGavppLvrLLssedeevqeeAawAL 36 
                 +  +++L ++L++e+++v+  +++AL
  EEA20946.1 166 SDLIDRLNKMLKDENPTVVSSVLAAL 191
                 5667888899*********9999998 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.28
                 HHHHHHTTTSSH CS
         Arm  15 ppLvrLLssede 26 
                 ppLv+LLs   +
  EEA20946.1 291 PPLVTLLSK-PP 301
                 9******93.33 PP

  == domain 4  score: 9.1 bits;  conditional E-value: 0.00067
                 HHHHHHHHTTTSSHHHHHHHHHHHHHHT CS
         Arm  13 avppLvrLLssedeevqeeAawALsNLa 40 
                 +++ L++L + + + +++eA+  ++N+ 
  EEA20946.1 396 CIDTLLELVHAKVPYIVQEATVVIRNIF 423
                 7*************************96 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.0     0.019        39      37      55 .]     102     120 ..      88     120 .. 0.79
   2 ?    4.7   0.0     0.023        45      25      52 ..     164     191 ..     142     192 .. 0.70
   3 ?    2.0   0.0      0.16   3.2e+02      28      50 ..     288     309 ..     279     309 .. 0.71
   4 ?   -2.3   0.0       3.4   6.8e+03       7      55 .]     378     385 ..     375     404 .. 0.64
   5 ?   -1.8   0.0       2.4   4.7e+03      40      54 ..     445     459 ..     442     460 .. 0.88
   6 ?   -2.4   0.1       3.9   7.7e+03      17      30 ..     499     512 ..     498     513 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.019
     HEAT_EZ  37 LnddsdeVRaaAagaLgnl 55 
                 + d +++VRa A+++++ +
  EEA20946.1 102 MDDHNPLVRALALRTISYI 120
                 344455*********9975 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.023
     HEAT_EZ  25 lvpeilpaLlalLnddsdeVRaaAagaL 52 
                 + +++++ L ++L+d++++V   ++ aL
  EEA20946.1 164 ESSDLIDRLNKMLKDENPTVVSSVLAAL 191
                 6789***************987777776 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.16
     HEAT_EZ  28 eilpaLlalLnddsdeVRaaAag 50 
                 ++ p+L+ lL ++++eV++ A++
  EEA20946.1 288 KLSPPLVTLL-SKPPEVQYLALR 309
                 4556666444.4777****9986 PP

  == domain 4  score: -2.3 bits;  conditional E-value: 3.4
     HEAT_EZ   7 AawaLGrlaggepellqplvpeilpaLlalLnddsdeVRaaAagaLgnl 55 
                 A++a+G                                          l
  EEA20946.1 378 AVRAIGK-----------------------------------------L 385
                 5555554.........................................3 PP

  == domain 5  score: -1.8 bits;  conditional E-value: 2.4
     HEAT_EZ  40 dsdeVRaaAagaLgn 54 
                 d++e +aa ++ +g+
  EEA20946.1 445 DEPEAKAAIIWIIGQ 459
                 889999*****9998 PP

  == domain 6  score: -2.4 bits;  conditional E-value: 3.9
     HEAT_EZ  17 gepellqplvpeil 30 
                 ++p   q+lvpe+l
  EEA20946.1 499 QRPTKGQQLVPEVL 512
                 689999*****998 PP

>> TIP120  TATA-binding protein interacting (TIP20)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.1     0.018        37      57     110 ..      48     102 ..      34     105 .. 0.83
   2 ?    8.2   0.1   0.00098       1.9      36      86 ..     138     189 ..     118     211 .. 0.80
   3 ?   -3.6   0.0       4.2   8.3e+03      66     101 ..     470     506 ..     456     513 .. 0.68

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.018
      TIP120  57 aldrldlselldrvlaGlsDe.hdikllcnlmlsklvalapeevlerldelveal 110
                 ++++ d+  l+  ++a ++    +ik +c+l l++++  +pe  l+ l  lv+ +
  EEA20946.1  48 TMSNNDMVGLFPDIIACMTIPsLEIKKMCFLYLVNYARAKPEIALKALPILVDDM 102
                 55778888899999998876669**********************9999888776 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.00098
      TIP120  36 vDdGLelRKaaYetlytlletaldrldlselldrvlaGlsDe.hdikllcnl 86 
                 vD    +RK+a  ++  l +++ + ++ s+l+dr+ + l+De   +    + 
  EEA20946.1 138 VDVDPYVRKTAAFCVAKLYDHHKKMVESSDLIDRLNKMLKDEnPTVVSSVLA 189
                 5666679***************9*******************5555544444 PP

  == domain 3  score: -3.6 bits;  conditional E-value: 4.2
      TIP120  66 lldrvlaGlsDe.hdikllcnlmlsklvalapeevle 101
                 ll+  la ++De  +++l  ++  +kl+  +p++ ++
  EEA20946.1 470 LLQDYLATFHDEpIEVQLALLTATVKLFIQRPTKGQQ 506
                 5566788888888888888888888888877776555 PP

>> T_hemolysin  Thermostable hemolysin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.0     0.077   1.5e+02      66     159 ..     131     227 ..      92     232 .. 0.74
   2 ?    9.3   0.0   0.00045       0.9      75     136 ..     369     429 ..     362     446 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.077
  T_hemolysin  66 epieqllserlgapvaReeivEvGnLassspga..arllilalarllaeaglewvvftatkqlrnllqrlglelteLaeAdperlge...eaeeWGsY 158
                  +p+++l+   ++  v+++  ++v++L+ +++++  ++ li  l ++l++++ + vv ++ ++l  + +r +   +++  A+++++ +   + +eWG+ 
   EEA20946.1 131 QPVKHLM-VDVDPYVRKTAAFCVAKLYDHHKKMveSSDLIDRLNKMLKDENPT-VVSSVLAALVDIWERSESISLTIDYASASKVVSvlaDCSEWGQT 226
                  5777777.4556678999999*****999877522677999999999988765.78888999999999988888888777777765411157899987 PP

  T_hemolysin 159 Y 159
                  Y
   EEA20946.1 227 Y 227
                  7 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.00045
  T_hemolysin  75 rlgapvaReeivEvGnLassspgaarllilalarllaeaglewvvftatkqlrnllqrlgle 136
                  +++ ++ R+ +  +G+La   ++aar+ i +l +l+ +a++ ++v  at  +rn++++   +
   EEA20946.1 369 EIDVHFVRKAVRAIGKLAIKIESAARQCIDTLLELV-HAKVPYIVQEATVVIRNIFRKYPNQ 429
                  5667789***********************999865.678****************997655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (718 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       548  (0.030565); expected 358.6 (0.02)
Passed bias filter:                      464  (0.0258799); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.66u 0.31s 00:00:00.97 Elapsed: 00:00:00.50
# Mc/sec: 4324.31
//
Query:       EEA20947.1  [L=351]
Description: kynureninase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.5e-07   29.5   0.1    1.6e-06   27.3   0.1    1.9  1  Aminotran_5      Aminotransferase class-V
  ------ inclusion threshold ------
      0.032   12.8   0.0      0.073   11.6   0.0    1.4  1  Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
      0.033   13.5   0.0      0.052   12.8   0.0    1.2  1  DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family


Domain annotation for each model (and alignments):
>> Aminotran_5  Aminotransferase class-V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.1   2.7e-10   1.6e-06     129     202 ..      69     147 ..      56     285 .. 0.85

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 2.7e-10
                  GGGHHHH-...-TTEEEEEEESBETTTTEB--HHHHHHHHHHTT-EEEEE-TTTTTTS---HHHHTESEEEEETTT..T CS
  Aminotran_5 129 ldelekll...nektklvaithvsnvtGtiqpveeigklakkkgalvlvDaaqavghipidvkklgvDflafsghK..l 202
                  ++++ k +   + +t+l+ +  ++  tG  ++++ i+++a+ kg+l+  D a avg  ++++++++vDf+a    K  +
   EEA20947.1  69 TEQILKVIddnASDTALILLPGIQFYTGQYFDIKTITAHAHSKGILIGWDCAHAVGNVELQLHDWDVDFAAWCHYKyvN 147
                  5566666633346799999999999*********************************************998888433 PP

>> Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   1.2e-05     0.073     129     218 ..      71     164 ..      65     174 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 1.2e-05
                      HHHHHCCT...TEEEEEEESS-TTTT----HHHHHHHHHHTT-EEEEEGTTTHT.TTS-GGGGT-SEEEEETTTTTTCSSS--EEEEEESSCHH CS
  Cys_Met_Meta_PP 129 elekaike...ntklvylEtptnpllkvvDiekiaklakkagvlvvvDntfasp.llqrplklgaDivvhSaTKylgGhsdvvaGvivvkgkee 218
                      ++ k+i++    t l++l  +   + +  Di++i++ a+++g+l+  D + a + +  +  ++++D       Ky++    ++aG+ v +++ +
       EEA20947.1  71 QILKVIDDnasDTALILLPGIQFYTGQYFDIKTITAHAHSKGILIGWDCAHAVGnVELQLHDWDVDFAAWCHYKYVNSGPGAMAGLFVHEKHGK 164
                      555566553336889999999999999*************************99677788899***********************99877555 PP

>> DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   8.7e-06     0.052     120     150 ..      94     124 ..      67     130 .. 0.94

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 8.7e-06
                      GGGB---HHHHHHHHHHCT-EEEEE-TT-TT CS
  DegT_DnrJ_EryC1 120 lyGqvadmdalkaiaakhglkvieDaAhAlG 150
                      + Gq +d++ ++a a+++g+ +  D+AhA+G
       EEA20947.1  94 YTGQYFDIKTITAHAHSKGILIGWDCAHAVG 124
                      67****************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (351 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       303  (0.0169); expected 358.6 (0.02)
Passed bias filter:                      298  (0.0166211); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.47u 0.24s 00:00:00.71 Elapsed: 00:00:00.40
# Mc/sec: 2657.17
//
Query:       EEA20948.1  [L=529]
Description: iron-sulfur cluster assembly accessory protein Isa2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.6e-12   46.9   0.0    6.7e-12   45.6   0.0    1.7  2  Fe-S_biosyn  Iron-sulphur cluster biosynthesis


Domain annotation for each model (and alignments):
>> Fe-S_biosyn  Iron-sulphur cluster biosynthesis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.6   0.0   3.8e-16   6.7e-12       1     110 [.     110     222 ..     110     223 .. 0.86
   2 ?   -3.8   0.0      0.83   1.5e+04      72      95 ..     401     422 ..     382     425 .. 0.60

  Alignments for each domain:
  == domain 1  score: 45.6 bits;  conditional E-value: 3.8e-16
                  -EEEE-HHHHHHHHHHHHCTTEC..EEEEEECCTSCCGGS.TT.EEEEEEEEESSTS.........TTTEEEEE.ETTEEEEEEGGGHHHS.TTEEEE CS
  Fe-S_biosyn   1 mkitlteaAaeklkkllaedkke..lrLdvddgggpyskggCsiggkyslvlvdeed.........eeydevle.snggkvyvksyslvfldeglvld 86 
                  m i+++++Aa++l++  ++++++  lr++v  gg       C+ g++y + l ++ +         e+ ++  +  +  +v++++ sl++l  g ++d
   EEA20948.1 110 MFIEISPRAAKRLSQITTSSEENqhLRVTVTSGG-------CH-GFQYLMSLEPSTKideaedtifEPAETDATgPGHARVVMDQASLELL-SGSTVD 198
                  89***************99777779*********.......**.****99999876666555566633333334366789***********.9***** PP

                  EEEETTEEEEEEETCCEEEEEEEE CS
  Fe-S_biosyn  87 fvedlgtlgLksdngilddnvglg 110
                  f+++l ++++k  n+ +++n+g++
   EEA20948.1 199 FTTELIGSQFKVINPRATSNCGCD 222
                  ***********************7 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 0.83
                  EGGGHHHS.TTEEEEEEEETTEEE CS
  Fe-S_biosyn  72 ksyslvfldeglvldfvedlgtlg 95 
                  +s+ +v +  g ++d+++  g ++
   EEA20948.1 401 ESKGEVKM--GITIDIKPRSGHIE 422
                  34444444..78888887776665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (529 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       519  (0.0289475); expected 358.6 (0.02)
Passed bias filter:                      440  (0.0245412); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.31s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 3485.14
//
Query:       EEA20949.1  [L=338]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.031   14.5   1.0        2.2    8.6   0.0    2.9  2  COX7C     Cytochrome c oxidase subunit VIIc
       0.15   10.9  30.5      0.023   13.6  25.6    2.0  3  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> COX7C  Cytochrome c oxidase subunit VIIc
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.0   0.00024       2.2      24      49 ..      14      39 ..       5      43 .. 0.76
   2 ?    3.1   0.5     0.013   1.2e+02      38      58 ..     168     188 ..     154     190 .. 0.74

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00024
                S.TTTSSSS--SSH.HHHHHHHHHHHHH CS
       COX7C 24 g.pysnLPFsknnK.ipfavkywgflgv 49
                g py+nLPF   +K + +++k  ++l++
  EEA20949.1 14 GaPYKNLPF--RQKlTSLGLKSALILAS 39
                56*******..55658888887777765 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.013
                 HHHHHHHHHHHHHHHHHHHHH CS
       COX7C  38 pfavkywgflgvgFalPFlav 58 
                 + ++  +++  +gF +PF+ v
  EEA20949.1 168 ATLISGTLVTLSGFYVPFMWV 188
                 55566678899*******976 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   1.8     0.018   1.6e+02     243     292 ..      31      79 ..       3      99 .. 0.55
   2 ?   13.6  25.6   2.6e-06     0.023     156     349 ..      65     249 ..      27     256 .. 0.66
   3 ?   -3.0   0.2      0.29   2.6e+03     154     166 ..     311     323 ..     296     330 .. 0.56

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.018
       MFS_1 243 lllaglllallalvgailallagrls.drlgrrrrlllallllllaalgla 292
                 l +a+  + ++ lv++ilal +g  +     +r    + +++llla++g++
  EEA20949.1  31 LKSAL--ILASTLVCLILALQWGGSVyPWSDSRVWGCFLGFGLLLALFGYM 79 
                 33444..44444444444444444442333334444444444444444444 PP

  == domain 2  score: 13.6 bits;  conditional E-value: 2.6e-06
       MFS_1 156 ilaivsllafvlfllllpeepperkrkspkeee.kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllall 253
                  + +++ll+++++++ + +++      s+ +       +++++ +++ l  + vl+ +++++ll + ++++ +++lp+y+q v+g + + ++g+ +  +
  EEA20949.1  65 CFLGFGLLLALFGYMQYHQKDEYVIAASTPTNAgLNLIRSQCLVPLRVLSQRSVLLGCIFSCLLQG-AMMTQTYYLPFYFQAVRGTD-AQTSGFSILPY 161
                 333444444444444443333333333332221222244455447999999999987777777776.88889***************.67777666666 PP

       MFS_1 254 alvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllll.vlvliGfglgfvfpsllalasdlappeeagtasglfntagslgg 349
                 ++ + i+ l++g l++  g   + ++ ++++++a  gl+++   ss+++ ++   v+ G+g+g+++++++a              s l+ +a++lgg
  EEA20949.1 162 GVTISIATLISGTLVTLSGFYVPFMWVGSGIFVAGSGLLYTLSRSSPFAKWFgYQVFTGTGYGVMVVLAAAD---IP------LGSTLVILAQCLGG 249
                 6666666*********99999999999999999999999999999999999956666777***876555443...33......44444445555555 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 0.29
       MFS_1 154 fyilaivsllafv 166
                 f+++ +++ +af+
  EEA20949.1 311 FLVAVGLGGVAFL 323
                 3333333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (338 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       587  (0.0327403); expected 358.6 (0.02)
Passed bias filter:                      329  (0.0183502); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.31s 00:00:00.87 Elapsed: 00:00:00.50
# Mc/sec: 2036.11
//
Query:       EEA20950.1  [L=201]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.3e-48  163.9   0.0    4.1e-48  163.6   0.0    1.0  1  GrpB      GrpB protein


Domain annotation for each model (and alignments):
>> GrpB  GrpB protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  163.6   0.0   2.3e-52   4.1e-48       2     153 ..      31     190 ..      30     193 .. 0.95

  Alignments for each domain:
  == domain 1  score: 163.6 bits;  conditional E-value: 2.3e-52
                 X--BS--THHHHHHHHHHHHHHHHH....EEEEEESGGGSTT--B-S-EEEEEEES-SGGGGGGHHHHHHTT-EE.-TTTTSTTEEEEEE-SSS...-- CS
        GrpB   2 velveydpeWpeqferekarlraal....isieHiGSTsvpglaAKpiiDilvvvedledeeelveaLeaagyellrgepgiperrlfvkgedee.ert 95 
                 +++ve++p+Wp++f  +kar+++ l    ++i H GSTsvpgl+AK++iDi++vv+dl de+++ve+Le++g+ +l +ep+++++r+fv + d+  + +
  EEA20950.1  31 ISIVEPNPAWPQRFLDTKARIETELgstaVAIFHAGSTSVPGLPAKDVIDIDLVVKDLMDEDSYVEPLERLGFIFLFREPDWHQHRFFVDEGDRPdAYP 129
                 89***********************998669********************************************99*************999987899 PP

                 EEEEEEETT-HHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHTT-...SS-HHHH----HHH CS
        GrpB  96 vhlhvveagspelerhllfrdyLrahpearaeYaalKrelaaka...eedidaYteaKeef 153
                 ++lhv+ +++pe+erh++fr++L + pe+   Ya++Kre+a +a   +e++++Yt++K+ +
  EEA20950.1 130 INLHVFGPDCPEVERHRIFREWLSTTPEDLLLYATVKRECAGAAeaaGESMQQYTDRKDMV 190
                 ****************************************9987454667********976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (201 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       317  (0.0176809); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 1453.23
//
Query:       EEA20951.1  [L=476]
Description: eukaryotic translation initiation factor 3 subunit EifCl, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.1e-160  535.1   0.0   1.3e-160  534.9   0.0    1.0  1  Paf67     RNA polymerase I-associated factor PAF67
  ------ inclusion threshold ------
      0.028   14.5   0.0       0.16   12.2   0.0    2.3  2  TPR_2     Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> Paf67  RNA polymerase I-associated factor PAF67
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  534.9   0.0  1.4e-164  1.3e-160       2     404 ..      76     474 ..      75     475 .. 0.97

  Alignments for each domain:
  == domain 1  score: 534.9 bits;  conditional E-value: 1.4e-164
       Paf67   2 rveSwenYceLfnlllnesespveleLpn.qWlwDiidEFvYQFqsfcqyrsklkkk..seeelkalkeensqvwsvesvlnvLhslvqkskineqlea 97 
                 +++S++nYc+Lf+++ln se+pv+le+p+  W wD+idEF+YQF+sfc+yr++++++  +eee+++l +en+++w ++svlnvL+sl+q+s+ineql+a
  EEA20951.1  76 KFASYDNYCSLFHYILN-SEGPVDLEVPSyYWAWDVIDEFIYQFESFCRYRNRVARTgsNEEEAQLL-RENPNTWGCYSVLNVLYSLIQRSQINEQLAA 172
                 689**************.**********978*********************999663244666666.999**************************** PP

       Paf67  98 ekegkeeeevagefgssplykmLgyFsligllrvhvllGdYttalkvlenidlskkallskvpaahvsllYyvGfaylmlrrYkDAirtlsqillyisr 196
                  k+g+++ +vage+gs+plykmLgyFs+igllrvh+llGd+++alk+l++i+++kka++++v+aah++++YyvGf+y+m+rrY+DAir++s+il+y+sr
  EEA20951.1 173 IKRGEDPLTVAGEYGSRPLYKMLGYFSIIGLLRVHCLLGDFSLALKTLDDIEMNKKAMFARVMAAHFTTYYYVGFSYMMMRRYADAIRMFSHILVYVSR 271
                 *************************************************************************************************** PP

       Paf67 197 tkqyqsrsyqsdqinkqadrmyaLlaiclalspskldesilqqlkekyseklsklqk...edeeafeelFskacPkfispaapdledaeaeedanseke 292
                 tk++q+ s+q+d+i+k++d+myaL+aic+a++p++ld++i+++l+eky+e++++lq+   e++  feelF+ acPkfisp++pd+++++ +       +
  EEA20951.1 272 TKNFQKGSSQYDAITKKNDQMYALIAICVAFHPTRLDDTIHTALREKYGEQFHRLQRggpEALPLFEELFRSACPKFISPTPPDFDNPAVN------ID 364
                 ***999***************************************************9888999***********************9754......89 PP

       Paf67 293 alkrqlklFlkevkqqkklptlrsylkLYttislekLasllevdeeelrsqLlslkhksrqlkwkkgsaslldgesvsasdldfyidedmihiaetkvq 391
                 ++++++ +F++evk++   pt++sylkLYtt++l+kLa +l+v+ e+lr++Ll+ k++srq++w +g   ll+ge ++asdld+ i++d+ihi+e+k  
  EEA20951.1 365 PVDHHTAIFMDEVKNTLFNPTVKSYLKLYTTMDLSKLAGFLDVEPEKLRAWLLVNKQRSRQIRWVEG--GLLEGEAITASDLDYAIEGDLIHISEAKAG 461
                 *****************************************************************96..99**************************** PP

       Paf67 392 rrygdyFlkqiek 404
                 rr  d++l+++++
  EEA20951.1 462 RRLVDWYLRNLTR 474
                 *********9875 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0      0.63   5.7e+03      10      22 ..     206     218 ..     205     221 .. 0.78
   2 ?   12.2   0.0   1.7e-05      0.16       3      25 ..     241     263 ..     239     268 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.63
       TPR_2  10 ayyklgdyeeAle 22 
                 ++  lgd+  Al+
  EEA20951.1 206 VHCLLGDFSLALK 218
                 5778999999987 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 1.7e-05
       TPR_2   3 alynlGlayyklgdyeeAleafe 25 
                  +y+ G +y+ + +y++A++ f 
  EEA20951.1 241 TYYYVGFSYMMMRRYADAIRMFS 263
                 69*****************9886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (476 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       510  (0.0284455); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 3188.01
//
Query:       EEA20952.1  [L=510]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      9e-51  173.2   0.0    1.3e-50  172.6   0.0    1.3  1  Paf1      Paf1


Domain annotation for each model (and alignments):
>> Paf1  Paf1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  172.6   0.0   7.5e-55   1.3e-50       1     408 [.      16     508 ..      16     510 .] 0.84

  Alignments for each domain:
  == domain 1  score: 172.6 bits;  conditional E-value: 7.5e-55
        Paf1   1 dliarirYsNnLPdppfdpKflkypfep.erfveyk.sssLerelkheiltdadlGmpldLinidgyldgdeesn....epvkLdpkDrkLLedeeask 93 
                 ++ia +rY+N+LP+p ++pKfl++p+e  erf  ++ +s+++r     i +da+ Gmp+dL++i+g+  gde+ +    +p+ +dp+D   L +     
  EEA20952.1  16 EYIASLRYRNDLPPPEMPPKFLDIPHEGlERFLAPGyASNMARREEPGIDVDAEGGMPIDLVGIPGLHLGDESAIlmpeNPPPVDPRDLPFLVPL---- 110
                 8**********************************************************************9999***99**********99999.... PP

        Paf1  94 asskrskqhskkVswLRrTEYistefnrfgvsatdkqetklgknlkkkeqeedlyrdresqika.iektFe....dakkplkdl............... 172
                  + k++++++ +Vs+LRrT Yi+ e  ++g+ + + +  +++   + ++++ +l++d + +ik+   k F+    ++k++ +d+               
  EEA20952.1 111 DQLKNPAVKNVNVSFLRRTQYIAIE--QRGPGGFKPAAGRVK--PR-ASEKTKLANDDPVYIKKyLMKGFDiaypQSKHTSEDTaerikghtpqkpeid 204
                 899**********************..666666333333333..33.367889999***************76664444444447778999******** PP

        Paf1 173 .....kHpskknlkaVealpllPDfelwknp..yaqvkfdgdpatdskekdlkeeeqkerlsqaiirpvmeeege........................ 240
                       Hp +++lk++   p++PD++  ++p  ++q kfd+ p+  +  k        +r+  +++ p    e                          
  EEA20952.1 205 awahpVHPDNPKLKPLGFFPVMPDLQGYPDPggFVQFKFDKPPLLAAAGKR------DDRIDVGLLYPSAPPE-Hileehdakarlhknnprlykdpgp 296
                 ***999***************************************444444......6899999999953332.24567788***************99 PP

        Paf1 241 .efv.ayflpteetlekrkr.............dleeeideeedeeyefklaReYnwkvenkaskgyee.nlllvfrd........d.kkkavyYnele 314
                   +  ++f+p+++ + ++ +             dl++++d + ++  ++ ++R Y +k ++ +s++++  + l +f+         d   ka+yY+++ 
  EEA20952.1 297 iPWDyDLFVPEKKGSVNKIKknldlsnsnrddeDLYTHDDGD-GKFHRYDRLRTYSTKAQQLNSEQKQRdIALTLFDPaksssgqaDdGIKAAYYYPIL 394
                 97756******99887777779*9999999999999997777.8899************77777555553777778888888877625789******** PP

        Paf1 315 trveLrkrRkk..............eeeeskkdklvvklrelneeelkarekresefdpleee......keeeeeeeeeeeeekseeeeekeeekeeae 393
                  +++L + R++                +e++ d++ v++r+++e e  +r   + ++dp  ++      ++ eeeeee e  +++ +++ + e +e+++
  EEA20952.1 395 GKMRLAPERARkiakaglarshgesSGREDQADQIHVTVRDPDEAEIYKRSLHRGNVDPEFKKnlpsppAQLEEEEEEIEVGNTQISADADAEADEDVA 493
                 ***********************973345899************************8887666888887555555555555555667777777777777 PP

        Paf1 394 eeseaeseeessdee 408
                 e +++++ ++ sd+e
  EEA20952.1 494 EHDSRPGRRDHSDDE 508
                 877888877777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (510 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       471  (0.0262703); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3555.27
//
Query:       EEA20953.1  [L=429]
Description: ATP-dependent protease (CrgA), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.4e-23   82.0   0.0    7.6e-23   81.5   0.0    1.2  1  LON_substr_bdg  ATP-dependent protease La (LON) substrate-bin
    6.3e-11   42.0   8.5    1.1e-10   41.2   8.5    1.4  1  zf-C3HC4_3      Zinc finger, C3HC4 type (RING finger)
    1.6e-09   37.4  12.8    9.7e-09   34.9   9.9    2.5  2  zf-C3HC4_2      Zinc finger, C3HC4 type (RING finger)
    1.5e-06   28.0  10.6    1.5e-06   28.0  10.6    1.7  2  zf-C3HC4        Zinc finger, C3HC4 type (RING finger)
    1.9e-06   28.1  10.9    1.9e-06   28.1  10.9    1.8  1  zf-RING_2       Ring finger domain
    9.4e-06   25.4   9.4    2.2e-05   24.2   9.2    1.7  2  Prok-RING_4     Prokaryotic RING finger family 4
    1.9e-05   24.6   8.0      4e-05   23.5   6.1    2.4  2  zf-RING_UBOX    RING-type zinc-finger
    2.1e-05   24.4   9.7      4e-05   23.5   9.7    1.5  1  zf-RING_5       zinc-RING finger domain
    0.00086   19.1   9.0    0.00086   19.1   9.0    2.1  2  zf-RING_4       RING/Ubox like zinc-binding domain
     0.0009   19.5   3.1      0.003   17.8   3.1    1.9  1  zf-rbx1         RING-H2 zinc finger domain
     0.0029   17.7  15.6      0.008   16.3  13.0    2.3  2  zf-C3HC4_4      zinc finger of C3HC4-type, RING
  ------ inclusion threshold ------
      0.041   14.0   8.2      0.081   13.1   8.2    1.5  1  zf-RING_10      zinc RING finger of MSL2
      0.046   13.9   0.0       0.19   11.9   0.0    2.0  2  CsgE            Curli assembly protein CsgE
       0.46   10.2   7.7          1    9.1   7.7    1.6  1  zf-P11          P-11 zinc finger


Domain annotation for each model (and alignments):
>> LON_substr_bdg  ATP-dependent protease La (LON) substrate-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.5   0.0   5.9e-26   7.6e-23       1     201 [.     188     406 ..     188     410 .. 0.85

  Alignments for each domain:
  == domain 1  score: 81.5 bits;  conditional E-value: 5.9e-26
  LON_substr_bdg   1 elpllpldnkvlfPgitlpltvsrpksiaaierlldkdkpyigvflv....kesqkdaide.esiselysvGtvarIvqilrlddgrikvvlegl 90 
                     elpl+++  ++ fP +++ l++++p+++ +i+r+ld++++++g++ +    + ++++     +s + + ++Gt +rI     l+dgri +++ g+
      EEA20953.1 188 ELPLFVC--TLAFPSTSTHLHIFEPRYRLMIRRALDSGNSKFGMVTHnfyhDLATEGH--PdRSPEPFMQYGTAVRIEWRDFLPDGRIMLTAVGM 278
                     699****..99**************************8778******76654555554..33589************77779************* PP

  LON_substr_bdg  91 eRvkikklekekeegylvaeveiiedd.....................s.epedsdslq.kelkalvqeiiekikkslarellkllleielllky 162
                      ++ki +  +   +gy++a +e+++d                      + +    + l+ ++l++ +++++ek +     +++   ++  ++   
      EEA20953.1 279 HKFKILRYGV--LDGYYRAHTERVDDIslaeeetlearelaaanqnnqPaNGSPLNALStQQLMQICMDFLEKQR-----MNSAPAVRERINRVF 366
                     ********88..9***********666**************99886541433333333378************99.....677777777777777 PP

  LON_substr_bdg 163 edlenpyr.LadlvaailpfsneekqelLeeldvedRlkk 201
                      + +  ++ + +++a++lp++ ee +++    +v++Rlk 
      EEA20953.1 367 GQPPTDPAiFPYWFANVLPIPDEEAYKIIPLTSVRERLKV 406
                     776666666*****************************95 PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.2   8.5   8.6e-14   1.1e-10       2      48 ..     100     145 ..      99     147 .. 0.94

  Alignments for each domain:
  == domain 1  score: 41.2 bits;  conditional E-value: 8.6e-14
                 GSB-TTTSSSBS-EEETTEEEEEE-HHHHHHHHHTT-B-TTT--B-- CS
  zf-C3HC4_3   2 deeCviClerprnvvllpCgHlvlCeeCaekllkrkkkCpiCrrpie 48 
                 +  C +C+    + ++ pCgH  +C+eCa+++++ ++ Cp+Cr++++
  EEA20953.1 100 ELDCRVCYGLIVDPCISPCGHS-FCYECANRIRDTSNLCPLCRKKMD 145
                 578*******************.*********99*********9976 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.9   9.9   7.6e-12   9.7e-09       2      40 .]     103     140 ..     102     140 .. 0.97
   2 ?    2.5   0.0       0.1   1.3e+02       3      11 ..     341     349 ..     341     354 .. 0.82

  Alignments for each domain:
  == domain 1  score: 34.9 bits;  conditional E-value: 7.6e-12
  zf-C3HC4_2   2 CpiCldmlkdpsvvtpCgHvfCqkCilrsLeekneCPlC 40 
                 C +C+  + dp  + pCgH+fC++C  r  + +n CPlC
  EEA20953.1 103 CRVCYGLIVDP-CISPCGHSFCYECANRIRDTSNLCPLC 140
                 ***********.****************989999***** PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.1
  zf-C3HC4_2   3 piCldmlkd 11 
                 +iC+d+l++
  EEA20953.1 341 QICMDFLEK 349
                 7******97 PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.0  10.6   1.1e-09   1.5e-06       1      41 []     103     140 ..     103     140 .. 0.96
   2 ?   -3.0   0.0       5.4   6.9e+03       2      11 ..     341     350 ..     341     352 .. 0.78

  Alignments for each domain:
  == domain 1  score: 28.0 bits;  conditional E-value: 1.1e-09
                 -TTT-S--SS-E.E-TTS--B-CHHHHHHHHCTSSB--TTT CS
    zf-C3HC4   1 CpiCleeakepnelleCkHsfCskCirkilksrkkvkCPlC 41 
                 C +C   +++p+ +++C+HsfC++C  +i++  +++ CPlC
  EEA20953.1 103 CRVCYGLIVDPC-ISPCGHSFCYECANRIRD--TSNLCPLC 140
                 ************.******************..7778**** PP

  == domain 2  score: -3.0 bits;  conditional E-value: 5.4
                 TTT-S--SS- CS
    zf-C3HC4   2 piCleeakep 11 
                 +iC++ ++++
  EEA20953.1 341 QICMDFLEKQ 350
                 6999998876 PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.1  10.9   1.5e-09   1.9e-06       2      44 .]     102     141 ..     101     141 .. 0.82

  Alignments for each domain:
  == domain 1  score: 28.1 bits;  conditional E-value: 1.5e-09
   zf-RING_2   2 eCpICleelssadsvlllpCgHvfhreClerwlrssstCPlCr 44 
                 +C +C+  +    ++++ pCgH+f++eC++r+  +s+ CPlCr
  EEA20953.1 102 DCRVCYGLIV---DPCISPCGHSFCYECANRIRDTSNLCPLCR 141
                 6****86664...344458************8888888****9 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.2   9.2   1.7e-08   2.2e-05       1      41 [.     103     145 ..     103     149 .. 0.86
   2 ?   -3.2   0.0       6.3     8e+03      20      41 ..     342     363 ..     340     364 .. 0.76

  Alignments for each domain:
  == domain 1  score: 24.2 bits;  conditional E-value: 1.7e-08
  Prok-RING_4   1 CvlCgeqekkailepCgHlvCkeCfdsk.dls.sCPlCqrris 41 
                  C +C     ++ ++pCgH +C eC +   d s  CPlC+++++
   EEA20953.1 103 CRVCYGLIVDPCISPCGHSFCYECANRIrDTSnLCPLCRKKMD 145
                  77888888899***************99744459******976 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 6.3
  Prok-RING_4  20 vCkeCfdskdlssCPlCqrris 41 
                  +C + ++++ ++s P  ++ri+
   EEA20953.1 342 ICMDFLEKQRMNSAPAVRERIN 363
                  7888888888888888777775 PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   6.1   3.1e-08     4e-05       1      38 [.     103     137 ..     103     138 .. 0.78
   2 ?    0.8   0.1      0.41   5.3e+02       1      11 [.     137     154 ..     137     162 .. 0.72

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 3.1e-08
  zf-RING_UBOX   1 CpIClelftdPlvlpCGHtFCreClwelskslegafkC 38 
                   C +C+ l  dP + pCGH+FC eC     + ++++  C
    EEA20953.1 103 CRVCYGLIVDPCISPCGHSFCYECA---NRIRDTSNLC 137
                   99*********4359*********9...4555555555 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.41
  zf-RING_UBOX   1 CpIClelft.......dP 11 
                   Cp C+  ++       +P
    EEA20953.1 137 CPLCRKKMDlsfregpNP 154
                   *****9998777777776 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   9.7   3.1e-08     4e-05       2      44 .]     103     142 ..     102     142 .. 0.95

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 3.1e-08
   zf-RING_5   2 CnkCfeklskeekfyltsCgHifCekClkkllekeavCpiCrk 44 
                 C +C+  +    ++++ +CgH+fC +C+++    ++ Cp+Crk
  EEA20953.1 103 CRVCYGLI---VDPCISPCGHSFCYECANRIRDTSNLCPLCRK 142
                 99999999...99****************************97 PP

>> zf-RING_4  RING/Ubox like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   9.0   6.7e-07   0.00086      16      46 ..     112     143 ..     103     145 .. 0.90
   2 ?   -3.1   0.0       5.5     7e+03      23      31 ..     341     349 ..     340     355 .. 0.71

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 6.7e-07
   zf-RING_4  16 kpC..eCgyqiClfCyhrileeeegrCPaCree 46 
                  pC  +Cg+ +C  C +ri+ ++++ CP Cr++
  EEA20953.1 112 DPCisPCGHSFCYECANRIR-DTSNLCPLCRKK 143
                 689889**************.67********97 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 5.5
   zf-RING_4  23 qiClfCyhr 31 
                 qiC++ +++
  EEA20953.1 341 QICMDFLEK 349
                 788887665 PP

>> zf-rbx1  RING-H2 zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   3.1   2.4e-06     0.003      27      55 .]     113     141 ..      87     141 .. 0.91

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 2.4e-06
     zf-rbx1  27 vvlGeCgHaFHlhCiskWlktrkvCPlcr 55 
                 + ++ CgH+F  +C ++  +t++ CPlcr
  EEA20953.1 113 PCISPCGHSFCYECANRIRDTSNLCPLCR 141
                 56789***********************8 PP

>> zf-C3HC4_4  zinc finger of C3HC4-type, RING
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3  13.0   6.3e-06     0.008       1      42 []     103     140 ..     103     140 .. 0.94
   2 ?    1.3   0.0       0.3   3.9e+02       3      10 ..     342     349 ..     341     350 .. 0.90

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 6.3e-06
  zf-C3HC4_4   1 CPiCldYLekPvsleCGhsfClsCisslqkepdgeqllCplC 42 
                 C++C  ++ +P   +CGhsfC +C +++   +     lCplC
  EEA20953.1 103 CRVCYGLIVDPCISPCGHSFCYECANRIRDTS----NLCPLC 140
                 ***************************98777....579999 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.3
  zf-C3HC4_4   3 iCldYLek 10 
                 iC+d+Lek
  EEA20953.1 342 ICMDFLEK 349
                 9*****97 PP

>> zf-RING_10  zinc RING finger of MSL2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   8.2   6.3e-05     0.081       1      45 [.     101     142 ..     101     161 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 6.3e-05
  zf-RING_10   1 lsCvvCckLLvdPlepkekeCqHyvCrlCvgkkkklkpsCsqCkd 45 
                 l C vC  L+vdP+ +    C+H+ C  C  + +     C+ C++
  EEA20953.1 101 LDCRVCYGLIVDPCIS---PCGHSFCYECANRIRDTSNLCPLCRK 142
                 67***********876...7*********9999999999999983 PP

>> CsgE  Curli assembly protein CsgE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   0.00015      0.19       3      47 ..     108     157 ..     106     162 .. 0.75
   2 ?   -2.1   0.0       3.5   4.5e+03      17      45 ..     292     320 ..     290     323 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00015
        CsgE   3 GLvidrtitrlGhdFyreFssywrdlps.....teefnltikErptaraG 47 
                 GL++d  i+ +Gh F +e ++++rd+++     ++++ l+ +E p ++ G
  EEA20953.1 108 GLIVDPCISPCGHSFCYECANRIRDTSNlcplcRKKMDLSFREGPNPAHG 157
                 9************************9431222245666666666666665 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 3.5
        CsgE  17 FyreFssywrdlpsteefnltikErptar 45 
                 +yr  ++++ d++  ee +l+ +E + a+
  EEA20953.1 292 YYRAHTERVDDISLAEEETLEARELAAAN 320
                 68889999999988888899999988775 PP

>> zf-P11  P-11 zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   7.7   0.00078         1       5      45 ..     103     144 ..     100     149 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00078
                 BTTTS.S--SSEEE-SSSEEEHHHHHHHHHHSSBETTTSSB- CS
      zf-P11   5 CksCW.fkdksLveCsdHYLClrClqllLsvserCpiCkkPL 45 
                 C+ C+    +  +    H  C +C + +   s++Cp+C+k +
  EEA20953.1 103 CRVCYgLIVDPCISPCGHSFCYECANRIRDTSNLCPLCRKKM 144
                 66666334566677778*********************9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (429 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       458  (0.0255452); expected 358.6 (0.02)
Passed bias filter:                      360  (0.0200792); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2793.15
//
Query:       EEA20954.1  [L=1312]
Description: cytosolic regulator Pianissimo, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
   7.5e-128  426.7   2.3   8.2e-128  426.5   0.4    2.0  3  RICTOR_N    Rapamycin-insensitive companion of mTOR, N-term
    9.5e-39  132.1   0.2    1.5e-35  121.9   0.0    3.7  4  RasGEF_N_2  Rapamycin-insensitive companion of mTOR RasGEF_N 
    8.3e-37  125.1   1.4    8.9e-34  115.4   0.3    4.7  5  RICTOR_M    Rapamycin-insensitive companion of mTOR, middle d
    7.3e-28   96.6   2.6    2.2e-26   91.9   0.0    4.2  5  RICTOR_V    Rapamycin-insensitive companion of mTOR, domain 5
    2.5e-16   59.5   8.6    5.6e-16   58.4   8.6    1.7  1  HR1         Hr1 repeat
  ------ inclusion threshold ------
        0.3   11.3   6.3        0.8    9.9   6.3    1.7  1  Uds1        Up-regulated During Septation
       0.73   10.0   2.6         11    6.2   0.1    3.4  3  Arm         Armadillo/beta-catenin-like repeat


Domain annotation for each model (and alignments):
>> RICTOR_N  Rapamycin-insensitive companion of mTOR, N-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  426.5   0.4  3.2e-131  8.2e-128       1     373 []     253     617 ..     253     617 .. 0.94
   2 ?   -3.9   0.0         2   5.2e+03      45      77 ..     779     811 ..     771     814 .. 0.75
   3 ?   -1.7   0.0      0.44   1.1e+03     220     268 ..     910     959 ..     883     965 .. 0.80

  Alignments for each domain:
  == domain 1  score: 426.5 bits;  conditional E-value: 3.2e-131
    RICTOR_N   1 vekandLvkllkrhpelkydlsleellkriqfmLldeskevraagyRilRylisdseslklllklkldiliirSLekdsksevEReqALkLirafleik 99 
                 +e+an+Lv+l+krhp+lkydl+++ +++r+q+mLl++s+ev+aagyR++Ry+i+d+ s++++++l++d l++ SL k+sk+++EReqALk+irafl++k
  EEA20954.1 253 IERANSLVELFKRHPTLKYDLEWSVFGQRVQMMLLSDSREVVAAGYRLTRYAIADRASIRTIRRLHTDELVTLSLVKESKASIEREQALKFIRAFLDVK 351
                 689************************************************************************************************ PP

    RICTOR_N 100 kgakelsksvvralvavaehedDrlrricletLaElllldpelvveagGlrvllnalldgsselaesllvallylLdspetrkylrkgldleillspft 198
                 +g++e+s++vvr++v++aeh++Drlr+i + tLaE+++ dp l++ agG+  l ++l++g+++++esl+  +l+++d+p++r+yl+ g +le +l+pft
  EEA20954.1 352 DGVHEISRAVVRTIVSIAEHHEDRLRNISIMTLAEIMVKDPGLIAYAGGIGPLHDTLAEGTFSASESLIGSFLHIMDTPHRRQYLHGGRELEAVLTPFT 450
                 *************************************************************************************************** PP

    RICTOR_N 199 dslekekkkesneeklqnsakaisslLksWsGlialsmnnfrplksLvsaLripslevrkaildllfdllrikppewsesflagrrltt..r.ansksq 294
                 ds +    ++ ++ +l++sakais +Lk+W+Gl++l++++++pl sL+++L++p ++ r+ il+llf+ l+ikpp+ws+sflagrrltt  r +n    
  EEA20954.1 451 DSFS----DTVRSGRLKCSAKAISAMLKTWPGLLVLARDKSKPLSSLLESLNYPDPNARDLILELLFEALQIKPPSWSSSFLAGRRLTTygRvTN---- 541
                 *544....899999***************************************************************************654222.... PP

    RICTOR_N 295 kkqeeneaeesaelkkkeserkrenlvdhylallllvlieaglleaLvevieeesdsslsrkatlLlgellklanrlLP 373
                    +e+ +++      +e++++r +l++h+ al+l+ l+eagl++aL  +ie e+++sl+rk+tlLl+e+lkla++ LP
  EEA20954.1 542 -LRSESDSKQL--RIFQENDKNRFDLTAHFSALVLATLLEAGLVKALSGLIEVENNQSLKRKSTLLLTEVLKLAQHSLP 617
                 .2233333333..333344456999***************************************************999 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 2
    RICTOR_N  45 gyRilRylisdseslklllklkldiliirSLek 77 
                 g  +lR l++++e +k+l + kl   i  +L++
  EEA20954.1 779 GCALLRTLMQTPEGIKYLAENKLLRQIAECLAQ 811
                 555788888888888888888888888888875 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 0.44
    RICTOR_N 220 aisslLksWsGlialsmnn.frplksLvsaLripslevrkaildllfdll 268
                   ++lL+ +    +l++nn    ++ Lv  L+ p ++v ++++++l + +
  EEA20954.1 910 FATKLLRKYAVGHHLAVNNvVWVVRMLVTQLYDPDISVCEVAVKILEEAC 959
                 55667777776677888886778999999999999999999999998776 PP

>> RasGEF_N_2  Rapamycin-insensitive companion of mTOR RasGEF_N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       3.3   8.4e+03      14      47 ..     286     319 ..     279     354 .. 0.79
   2 ?   -3.3   0.0       4.6   1.2e+04      10      34 ..     493     517 ..     490     521 .. 0.86
   3 !    5.7   0.0    0.0075        19      46      81 ..     770     804 ..     737     807 .. 0.80
   4 !  121.9   0.0   5.8e-39   1.5e-35       4     105 ..     930    1031 ..     927    1034 .. 0.97

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 3.3
  RasGEF_N_2  14 LydqsrevvaaaleiLeeacddkeslevlvelkp 47 
                 L  +srevvaa  ++   a+ d++s++++ +l++
  EEA20954.1 286 LLSDSREVVAAGYRLTRYAIADRASIRTIRRLHT 319
                 5567899999999999999999999998888777 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 4.6
  RasGEF_N_2  10 lvnqLydqsrevvaaaleiLeeacd 34 
                 l+++L+ ++++ ++ +le+L ea++
  EEA20954.1 493 LLESLNYPDPNARDLILELLFEALQ 517
                 8899999999999999999999976 PP

  == domain 3  score: 5.7 bits;  conditional E-value: 0.0075
  RasGEF_N_2  46 kpslqhlgeigslLllkllstssGfkylqelnfvee 81 
                 kp+  ++   g  Ll +l++t++G+kyl e++ +++
  EEA20954.1 770 KPNQRYV-RTGCALLRTLMQTPEGIKYLAENKLLRQ 804
                 4444555.57889***************99887665 PP

  == domain 4  score: 121.9 bits;  conditional E-value: 5.8e-39
  RasGEF_N_2    4 kWgiellvnqLydqsrevvaaaleiLeeacddkeslevlvelkpslqhlgeigslLllkllstssGfkylqelnfveeeldkWiekkneeYvklvEe 100 
                   W++++lv+qLyd++ +v+++a++iLeeac+++e+le++v+++psl+hlgeig++Lll++lsts G++yl+ l+++++e+d+W+  +n  Yv lvE+
  EEA20954.1  930 VWVVRMLVTQLYDPDISVCEVAVKILEEACNQREYLEYVVKCRPSLDHLGEIGAPLLLRFLSTSVGYHYLDGLDYITQEMDDWFLGRNDAYVALVEA 1026
                  6************************************************************************************************ PP

  RasGEF_N_2  101 alaea 105 
                   l++a
  EEA20954.1 1027 SLSRA 1031
                  *9987 PP

>> RICTOR_M  Rapamycin-insensitive companion of mTOR, middle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0     0.035        90      22      52 ..     778     808 ..     764     815 .. 0.80
   2 !  115.4   0.3   3.5e-37   8.9e-34       2     103 ..     817     918 ..     816     919 .. 0.97
   3 ?    0.1   0.0      0.27     7e+02      29      51 ..    1064    1086 ..    1060    1103 .. 0.79
   4 ?   -3.0   0.0       2.4   6.2e+03      28      56 ..    1112    1140 ..    1108    1157 .. 0.82
   5 ?   -0.2   0.0      0.33   8.5e+02      18      40 ..    1144    1166 ..    1138    1170 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.035
    RICTOR_M  22 gYfkfiGvlsssknGlklLekwkiftllykl 52 
                 +  +++ +l+++++G+k L + k+   + ++
  EEA20954.1 778 TGCALLRTLMQTPEGIKYLAENKLLRQIAEC 808
                 5557899**************9999888766 PP

  == domain 2  score: 115.4 bits;  conditional E-value: 3.5e-37
    RICTOR_M   2 gvsagepllskerleetlsrgYfkfiGvlsssknGlklLekwkiftllyklvelksrddllklilssldysvdghiRiilskaLtnssekiRlyatkhL 100
                 g ++ +pl+s+e++ +tls gYf+++Gvlss+ +Gl+++e+w++ +++y+++elk+r dl++++l ++d+++++h+R++lskaLt++s++iRl+atk+L
  EEA20954.1 817 GLTSASPLFSREQMASTLSGGYFALLGVLSSDTKGLSMMERWHMTNMFYHIIELKDRADLIQALLGNMDFTLESHLRVLLSKALTAGSKDIRLFATKLL 915
                 6788899******************************************************************************************** PP

    RICTOR_M 101 rkl 103
                 rk+
  EEA20954.1 916 RKY 918
                 *97 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.27
    RICTOR_M   29 vlsssknGlklLekwkiftllyk 51  
                   l ++++G klLe+++ f  + +
  EEA20954.1 1064 ELARTSEGCKLLEHSGHFLEFAS 1086
                  5889**********998876655 PP

  == domain 4  score: -3.0 bits;  conditional E-value: 2.4
    RICTOR_M   28 GvlsssknGlklLekwkiftllyklvelk 56  
                  G + s + G  +Le+++i + + +++e+ 
  EEA20954.1 1112 GNVGSMELGAPFLEETEIVQDIVNIAEQA 1140
                  666677789999*******9999998875 PP

  == domain 5  score: -0.2 bits;  conditional E-value: 0.33
    RICTOR_M   18 tlsrgYfkfiGvlsssknGlklL 40  
                  t+  + f  +G++s+s++Gl++ 
  EEA20954.1 1144 TMRGTAFFVLGLISRSQHGLEMV 1166
                  566677899***********986 PP

>> RICTOR_V  Rapamycin-insensitive companion of mTOR, domain 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       1.9     5e+03      27      39 ..     360     372 ..     345     383 .. 0.81
   2 ?   -0.1   0.0      0.43   1.1e+03      15      38 ..     788     811 ..     785     816 .. 0.81
   3 ?   -0.8   0.0      0.71   1.8e+03      44      66 ..     834     856 ..     827     859 .. 0.83
   4 ?   -0.9   0.0       0.8   2.1e+03      55      69 ..    1065    1079 ..    1064    1079 .. 0.87
   5 !   91.9   0.0   8.7e-30   2.2e-26       1      71 []    1102    1172 ..    1102    1172 .. 0.98

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 1.9
    RICTOR_V  27 divedivelaees 39 
                  +v +iv++ae++
  EEA20954.1 360 AVVRTIVSIAEHH 372
                 7999******987 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.43
    RICTOR_V  15 sselGielldeydivedivelaee 38 
                 ++++Gi++l e++++ +i+e   +
  EEA20954.1 788 QTPEGIKYLAENKLLRQIAECLAQ 811
                 6899***99999999999987655 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 0.71
    RICTOR_V  44 lRGtafyvLglissteegaeiLd 66 
                 l G  f  Lg++ss ++g  +++
  EEA20954.1 834 LSGGYFALLGVLSSDTKGLSMME 856
                 56778999**********99987 PP

  == domain 4  score: -0.9 bits;  conditional E-value: 0.8
    RICTOR_V   55 issteegaeiLdelg 69  
                  +++t+eg+++L+  g
  EEA20954.1 1065 LARTSEGCKLLEHSG 1079
                  699********9765 PP

  == domain 5  score: 91.9 bits;  conditional E-value: 8.7e-30
    RICTOR_V    1 lklKaaLWaiGhigsselGielldeydivedivelaeespvlslRGtafyvLglissteegaeiLdelgWe 71  
                  lk+K++LWa+G++gs+elG+++l+e++iv+div++ae+++v+++RGtaf+vLglis++++g e+  e+gW+
  EEA20954.1 1102 LKVKGCLWAVGNVGSMELGAPFLEETEIVQDIVNIAEQADVITMRGTAFFVLGLISRSQHGLEMVYEAGWD 1172
                  589*******************************************************************6 PP

>> HR1  Hr1 repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.4   8.6   2.2e-19   5.6e-16       2      67 ..     123     190 ..     122     192 .. 0.92

  Alignments for each domain:
  == domain 1  score: 58.4 bits;  conditional E-value: 2.2e-19
         HR1   2 leelekklekElkireGAenllralesk.ktqnkkvrqeaeselsesnskielLreqL.eelqasvqn 67 
                  ++++++++kE+ki+ G en+l+al +k ++q +++r ++esels+sn+k+++Lr++L  el++s+++
  EEA20954.1 123 QAAIRDRIAKEMKIKVGTENMLEALLTKsAKQTRDQRLRVESELSSSNRKLAELRQELeDELMRSQTP 190
                 689***********************999*****************************6677776665 PP

>> Uds1  Up-regulated During Septation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   6.3   0.00031       0.8      29     111 ..     115     186 ..     106     193 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00031
        Uds1  29 elkaLeerlealrkkLaletklrdaarsLsrlyssskksakssaarsnskssreslakaeeelaeserkvdelaselekleer 111
                 e  + e+r  a+r ++a e+k++ +++++ ++  +++++           ++r++ ++ e+el++s+rk  el +ele    r
  EEA20954.1 115 EADTTEQRQAAIRDRIAKEMKIKVGTENMLEALLTKSAK-----------QTRDQRLRVESELSSSNRKLAELRQELEDELMR 186
                 5667799********************999988666555...........567899*********************875555 PP

>> Arm  Armadillo/beta-catenin-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.1      0.11   2.9e+02       7      30 ..     575     599 ..     573     606 .. 0.81
   2 ?    6.2   0.1    0.0045        11      13      33 ..     932     952 ..     932     959 .. 0.91
   3 ?   -2.0   0.0       1.7   4.3e+03      30      38 ..    1105    1113 ..    1104    1114 .. 0.85

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.11
                 HHHHTTHHHHHHHHTT.TSSHHHHH CS
         Arm   7 avieaGavppLvrLLs.sedeevqe 30 
                 ++ eaG v++L  L++   ++++++
  EEA20954.1 575 TLLEAGLVKALSGLIEvENNQSLKR 599
                 6889************777776665 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.0045
                 HHHHHHHHTTTSSHHHHHHHH CS
         Arm  13 avppLvrLLssedeevqeeAa 33 
                 +v+ Lv+ L+++d +v+e+A+
  EEA20954.1 932 VVRMLVTQLYDPDISVCEVAV 952
                 699****************98 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 1.7
                  HHHHHHHHH CS
         Arm   30 eeAawALsN 38  
                  + ++wA++N
  EEA20954.1 1105 KGCLWAVGN 1113
                  679*****9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1312 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       891  (0.049696); expected 358.6 (0.02)
Passed bias filter:                      558  (0.0311228); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.92u 0.28s 00:00:01.20 Elapsed: 00:00:00.46
# Mc/sec: 8531.23
//
Query:       EEA20955.1  [L=302]
Description: urate oxydase UaZ [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-80  268.3   1.8    2.3e-43  147.6   0.5    2.0  2  Uricase   Uricase
  ------ inclusion threshold ------
      0.025   14.4   0.0      0.038   13.8   0.0    1.3  1  Mob_Pre   Plasmid recombination enzyme
       0.13   12.4   0.1       0.25   11.5   0.1    1.4  1  DUF4825   Domain of unknown function (DUF4825)


Domain annotation for each model (and alignments):
>> Uricase  Uricase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  147.6   0.5   3.8e-47   2.3e-43       2     130 ..       9     134 ..       8     135 .. 0.96
   2 !  120.3   0.0     1e-38   6.2e-35       3     131 .]     146     291 ..     144     291 .. 0.97

  Alignments for each domain:
  == domain 1  score: 147.6 bits;  conditional E-value: 3.8e-47
                 EEEEEEEEEEEE.EETTCBEBECEEEECCEEEEEESSEEECCHHH-STTT---CCHHHHHHHHHHHHH--SSHH.HHHHHHHHHHHC-TTEEEEEEEEE CS
     Uricase   2 kyGkddvrvlkv.rkstgsafhgfvedevttllegkdrilstyfagdnsdvvasdSvkntvYkmakkhgvespe.Falllakhflekyphveevsvslp 98 
                 +yGkd+vrv+kv r+ ++++f+++ve++v++lleg d i+ +y+++dns vva+dS+knt++ +ak+h+v++pe F++++++hf+eky+h+++++v++ 
  EEA20955.1   9 RYGKDNVRVYKVhRD-EKTGFQTVVEMTVCCLLEG-D-IDVSYTKADNSVVVATDSIKNTIFILAKQHPVTTPEvFGSIIGSHFIEKYSHIHAAHVNII 104
                 8***********877.6679***************.*.************************************************************* PP

                 EEEEEEEEECCSSEEEEEECEEEECCCCEEEE CS
     Uricase  99 nkhwervdlwgtgkphahafvftpsekptgli 130
                 +++w+r+++  +gkph+h+f++++ e++++++
  EEA20955.1 105 THRWTRMTI--DGKPHPHSFLRDGAETRNVQV 134
                 *********..669***************987 PP

  == domain 2  score: 120.3 bits;  conditional E-value: 1e-38
                 EEEEEEEEEEEEETTCBEBECEEEECCEEEEEESSEEECC.....................................HHH-STTT---CCHHHHHHHHH CS
     Uricase   3 yGkddvrvlkvrkstgsafhgfvedevttllegkdrilst.....................................yfagdnsdvvasdSvkntvYkm 64 
                 + ++++ vlk   stgs+f+gfv+de+ttl+e++drilst                                     +fa++n     s+Sv++t+Y+m
  EEA20955.1 146 STIQGLHVLK---STGSQFWGFVRDEYTTLPEVWDRILSTevdatwnwknfsslaevqadparfdnawsaareitlsTFAKEN-----SASVQATMYNM 236
                 7899******...**********************************************************************.....*********** PP

                 HHHH--SSHHHHHHHHHHHHHC-TTEEEEEEEEEEEEEEEEEE.CC..SSEEEEEECEEEECCCCEEEEE CS
     Uricase  65 akkhgvespeFalllakhflekyphveevsvslpnkhwervdl.wg..tgkphahafvftpsekptglie 131
                 a++               +l+ +p+ve+v++slpnkh+++vdl w+   +++ ++a+vf+p++ p+gli+
  EEA20955.1 237 ANQ---------------ILAVVPQVETVEYSLPNKHYFEVDLkWHkgLKNTGKDAEVFAPQSGPNGLIK 291
                 ***...............****************************7733689***************95 PP

>> Mob_Pre  Plasmid recombination enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   6.4e-06     0.038     109     136 ..       4      31 ..       1      66 [. 0.87

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 6.4e-06
                 HHHHHHH-GGGEEEEEEETSSSS-EEEE CS
     Mob_Pre 109 kffeeryGkenvlsAvvHlDEatpHmHl 136
                 k+++ ryGk+nv+   vH+DE+t  +++
  EEA20955.1   4 KLAAARYGKDNVRVYKVHRDEKTGFQTV 31 
                 77899******************98776 PP

>> DUF4825  Domain of unknown function (DUF4825)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.1   4.2e-05      0.25      53      88 ..     222     257 ..     213     263 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 4.2e-05
     DUF4825  53 tekeeeelkeelkknavillaLidNldsvtfeledd 88 
                 +++++  +++++++ a  +la+++ +++v+++l+++
  EEA20955.1 222 AKENSASVQATMYNMANQILAVVPQVETVEYSLPNK 257
                 4566667788**********************9984 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (302 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       572  (0.0319036); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 2029.85
//
Query:       EEA20956.1  [L=175]
Description: 50S ribosomal protein L13 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.7e-42  143.5   0.1    4.9e-42  143.1   0.1    1.1  1  Ribosomal_L13  Ribosomal protein L13


Domain annotation for each model (and alignments):
>> Ribosomal_L13  Ribosomal protein L13
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  143.1   0.1   2.7e-46   4.9e-42       2     122 ..      16     139 ..      15     141 .. 0.96

  Alignments for each domain:
  == domain 1  score: 143.1 bits;  conditional E-value: 2.7e-46
                    EEEEE..ETTSBHHHHHHHHHHHHHTTTSTT--TTS--S-EEEEEEGGCBB-SSTHHTT-EEEEE-SSTTSEEEEEHHHHHCCSH.HHHHHHHHHC CS
  Ribosomal_L13   2 WyviD..AegqvlgrlaskiakvLrGkhkptytphvdcGdyvvvinaekvaltgkkleqkvyyrhtgypgglkevtakellekkp.eeilekaVkg 94 
                    W+ iD   +g++lgr+as ia++L+Gkhkp+y+p++dcGdyvv + ++++++tgkk  qk+yy+ht++pg+lk++t+++++ek    e+l++aV+g
     EEA20956.1  16 WHYIDvgTDGRSLGRVASAIAMHLMGKHKPIYDPSTDCGDYVVAVGCHDLHTTGKKRLQKKYYTHTTRPGSLKSMTMDKMFEKWGgGEVLKRAVRG 111
                    ****9877899************************************************************************8769********* PP

                    CS-SSHHHHHHGCTEEEESSSTTSGGGG CS
  Ribosomal_L13  95 mLpknklgrrrlkrLkvyageehpheaq 122
                    mLpkn+l+++rl rLk ++g +hp++++
     EEA20956.1 112 MLPKNRLRDKRLARLKTFEGLQHPYKKN 139
                    ************************9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (175 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       283  (0.0157845); expected 358.6 (0.02)
Passed bias filter:                      255  (0.0142228); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.44
# Mc/sec: 1195.50
//
Query:       EEA20957.1  [L=143]
Description: 40S ribosomal protein Rps16, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.5e-33  115.9   0.4    1.7e-33  115.7   0.4    1.0  1  Ribosomal_S9  Ribosomal protein S9/S16


Domain annotation for each model (and alignments):
>> Ribosomal_S9  Ribosomal protein S9/S16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.7   0.4   9.4e-38   1.7e-33       1     121 []      11     143 .]      11     143 .] 0.94

  Alignments for each domain:
  == domain 1  score: 115.7 bits;  conditional E-value: 9.4e-38
                   EECTTEEEEEEEEESSSEEEETTEECCHHSTTSCHHHHHCHHHHHTTTSS..SEEEEEEEESS-HHHHHHHHHHHHHHHHHHHHH.....HHHHHHC CS
  Ribosomal_S9   1 GrrKesvArvwikegkgkilvngksleeYfkeeaarekvleplkltgllg..kfdvfvkvkgGGlsgqaeAirlgiaraLvalek.....eekkeLk 90 
                   G++K+++A ++ k+gkg i+vng++l+  +k e+ r kv+epl ++gl +   +d++v+v+gGG+++q++Air++ia+ +va+++     ++k++Lk
    EEA20957.1  11 GKKKTATAVAHTKQGKGLIKVNGQPLNL-VKPEQLRFKVYEPLLIVGLDKfaGVDIRVRVTGGGHVSQIYAIRQAIAKSIVAYYQkfvdeHSKNQLK 106
                   89**************************.877***************988745******************************98888744599999 PP

                   ......TCCCTS-B--------TTSSCTTB----S-- CS
  Ribosomal_S9  91 ......kaglltrDpRvvErkKtgkkkARkkyqwskR 121
                         +++ll++D+R+ E+kK+g ++AR++yq+s+R
    EEA20957.1 107 qafiqyDRTLLVADSRRAEPKKFGGPGARARYQKSYR 143
                   8888888****************************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (143 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       623  (0.0347482); expected 358.6 (0.02)
Passed bias filter:                      496  (0.0276647); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.26s 00:00:00.65 Elapsed: 00:00:00.40
# Mc/sec: 1062.93
//
Query:       EEA20958.1  [L=465]
Description: AAR2 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.2e-100  337.4   0.0   1.4e-100  337.1   0.0    1.0  1  AAR2      AAR2 protein


Domain annotation for each model (and alignments):
>> AAR2  AAR2 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  337.1   0.0  7.9e-105  1.4e-100       2     351 ..       7     404 ..       6     405 .. 0.87

  Alignments for each domain:
  == domain 1  score: 337.1 bits;  conditional E-value: 7.9e-105
        AAR2   2 gatlllldlpegtefGiDlksftvgpkFkGikmiPpGvHfvyysaasstselslrsgfffy.......................fkkgevivkkwdkee 77 
                 ++t++l  lp++t++G+Dl+sft++++F Gi +++pG+Hf+y+++   t+++s+r+g++fy                       ++++e+++++w+++ 
  EEA20958.1   7 TPTIILPRLPAKTLVGLDLLSFTSTEQFYGISDLTPGWHFLYTGT---TESFSIRCGAWFYvgdishdstsdgsksiilhsgaaTGGPEIRIWRWNQDI 102
                 789******************************************...99*********************************9999************ PP

        AAR2  78 EdLve.....elseeeaerykanlksiefdkkLapYpsdasek..................WksltshIteellerilp.esgkisstaelasseseae 152
                 E+L++      +++ e++r+kanl+ + + + L++Y+++ + +                  W +lt+++t+e+l+ril+    +  +            
  EEA20958.1 103 ETLIPmrgddGENRLEIMRWKANLGGLRQMGALFSYKTKGLPDnteidendatdqsptrkdWIQLTNRLTPEILSRILGtP--YSDD------------ 187
                 ********9989999**********9*************7766778888888888899999******************21..1112............ PP

        AAR2 153 sekkkawskssseeskgssakrdeeelpslkskegtelr.................FteiplkrtwpegatgrelTkaalDkSwaLedllrksssgd.. 232
                  +++++w+ +s     +s+a+rd e++p+++ +  +e+r                 F++i+lkrtw+ega+gre+T+aa+DkSwaL+dl+ ++s +   
  EEA20958.1 188 -DDRPSWNINS-----ASTAARDAENIPGITAEIASEVRtkafesgqeskkekelqFLPIDLKRTWREGAIGRERTEAAQDKSWALGDLIGRYSLSGns 280
                 .2334444444.....4444445555555554444444444555555555555555*************************************987789 PP

        AAR2 233 ....eaelLgElqfaFvlflllqnyssfeqWkrllsLlltceeaikerpdlfvkflrvLraqLkelpe.....flsdivskdnfLkkllkkfrenleee 322
                     e e+LgElqf+F+++l+l+nys++eqWkrllsL+ltc+ ai+er+ +f+++l++Lr+qL+++++     f +d   ++nfL+kll+ fr+++++ 
  EEA20958.1 281 gkkgEGEILGELQFCFLMILTLMNYSCLEQWKRLLSLILTCRIAIREREPFFRDVLQLLRLQLRHCEDvdgglFEMDGDYDGNFLRKLLTGFRQTIYQI 379
                 ********************************************************************77766555533389****************5 PP

        AAR2 323 eeeeeeesklkkelekLekllkekfgWdl 351
                 e++    +++++e+++Le+++++++gW+l
  EEA20958.1 380 EGA----DTVRQEMNALEQWVRTEYGWEL 404
                 555....7********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (465 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       336  (0.0187406); expected 358.6 (0.02)
Passed bias filter:                      314  (0.0175135); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.41
# Mc/sec: 3396.46
//
Query:       EEA20959.1  [L=279]
Description: glutathione S-transferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-12   47.8   0.0    2.8e-12   46.9   0.0    1.4  1  GST_N_3   Glutathione S-transferase, N-terminal domain
    1.6e-12   47.6   0.0    3.8e-12   46.4   0.0    1.7  2  GST_N     Glutathione S-transferase, N-terminal domain
    2.2e-10   40.7   0.0    4.2e-10   39.8   0.0    1.5  1  GST_N_2   Glutathione S-transferase, N-terminal domain
    6.5e-09   35.9   0.0    1.1e-08   35.1   0.0    1.3  1  GST_C     Glutathione S-transferase, C-terminal domain
    2.5e-08   34.0   0.0    4.6e-08   33.2   0.0    1.4  1  GST_C_3   Glutathione S-transferase, C-terminal domain
      0.004   17.1   0.0       0.01   15.9   0.0    1.7  1  GST_C_2   Glutathione S-transferase, C-terminal domain
  ------ inclusion threshold ------
      0.057   13.7   0.1       0.14   12.5   0.0    1.6  2  Tom37     Outer mitochondrial membrane transport complex prot


Domain annotation for each model (and alignments):
>> GST_N_3  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.9   0.0   1.1e-15   2.8e-12       8      72 ..      65     132 ..      60     143 .. 0.90

  Alignments for each domain:
  == domain 1  score: 46.9 bits;  conditional E-value: 1.1e-15
                 HHHHHHHHHHHHHT--EEEE---TTT.THHHHHHH-TT--SSEEETTS-..EEESHHHHHHHHHHHH- CS
     GST_N_3   8 pyarrvrlaLnekglpvevvevtpge.hdeellaknplgkvPvLeddge..altdSlaIidyLeelyp 72 
                 p+ ++v+++L+e+ lp+++  ++ ++ + e++l+++p+g++P+L+d+++   l++S aIi yL ++y+
  EEA20959.1  65 PNPWKVAMVLEELSLPYQINYLELTDvKTESYLEVTPNGRLPALRDPNTgiTLWESGAIILYLVDQYD 132
                 889****************9999888569****************985555***************98 PP

>> GST_N  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.4   0.0   1.5e-15   3.8e-12       2      75 ..      55     128 ..      54     129 .. 0.95
   2 ?   -3.5   0.0       5.4   1.4e+04      40      57 ..     144     163 ..     137     163 .. 0.63

  Alignments for each domain:
  == domain 1  score: 46.4 bits;  conditional E-value: 1.5e-15
                 EEEEESSSTSHTHHHHHHHHHHTT-EEEEEEECSTTTCGGCHHHHHHCTTS-SSEEEET..TEEEESHHHHHHHHH CS
       GST_N   2 vltlysirgsprahrirlllaakgveyevvpldfeageekspellklnplgkvPaLedn..gkkltESraIleYia 75 
                 +l l++++g p+++++ ++l+++ ++y++  l++++ ++  + +l + p+g++PaL d+  g +l+ES+aI  Y++
  EEA20959.1  55 TLELWGHWGAPNPWKVAMVLEELSLPYQINYLELTDVKT--ESYLEVTPNGRLPALRDPntGITLWESGAIILYLV 128
                 689*******************************88855..9********************************96 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 5.4
                 GGC..HHHHHHCTTS-SSEE CS
       GST_N  40 eks..pellklnplgkvPaL 57 
                 ek   +++l  +  g+ P++
  EEA20959.1 144 EKYlcQQWLAFQISGQGPYF 163
                 44445777777777888876 PP

>> GST_N_2  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.8   0.0   1.6e-13   4.2e-10       3      68 ..      65     128 ..      63     130 .. 0.89

  Alignments for each domain:
  == domain 1  score: 39.8 bits;  conditional E-value: 1.6e-13
                 HHHHHHHHHHHHCT--EEEEEEH...-TTSHHHHHHHHCTTTSSSEEE-C.TTEEEESHHHHHHHHH CS
     GST_N_2   3 PwahRvlialalkglediisvvvlepkgfekseefprlnprgtVPvLwdk.dgqvineSseIlryle 68 
                 P +++v ++l+++ l+++i+ +   +  + k+e +++++p+g +P+L d+ +g  ++eS +I+ yl 
  EEA20959.1  65 PNPWKVAMVLEELSLPYQINYL---ELTDVKTESYLEVTPNGRLPALRDPnTGITLWESGAIILYLV 128
                 889******************9...45566678*****************6666***********95 PP

>> GST_C  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.1   0.0   4.4e-12   1.1e-08       6      93 .]     164     259 ..     161     259 .. 0.88

  Alignments for each domain:
  == domain 1  score: 35.1 bits;  conditional E-value: 4.4e-12
                 HHHHHHHHSTTHHHHHHHHHHHHHHHHHHHHHHHHHHH....TSSSSSTTSSCHHHHHHHHHHHHHHHHTTTTT.....TTTSHHHHHHHHHHHTSH CS
       GST_C   6 sqilllfyvkaeekkeelvdealekvaevlsaleeelk....kqdylvGdkltlADialvpilnwlqrlglafg.....qekfpnlkawlerimarp 93 
                 +q++++  +++ ek +++ d   +++ +v+s+++  l+       +lvGdk t+AD+ +++++++ + l  ++g     ++++pn ++w+ ++ +++
  EEA20959.1 164 GQATWFARFHP-EKIQSAIDRYINEILRVISVIDLGLRrnpaAGNWLVGDKCTYADLSFATWALVGYGLLKELGkneglEKDYPNYTQWIAKMEEQE 259
                 68899999999.799999*****************9999999999*******************66666666666666***************9986 PP

>> GST_C_3  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.2   0.0   1.8e-11   4.6e-08      30      94 ..     189     263 ..     162     265 .. 0.69

  Alignments for each domain:
  == domain 1  score: 33.2 bits;  conditional E-value: 1.8e-11
                 HCHHHHHHHHHH.C.HGTSSSSTTS--HHHHHHHHHHHHHHHH........TCCCC-HHHHHHHHHHHTSHHHHH CS
     GST_C_3  30 pkflkyfekvlk.k.kgggylvgdklTyADlalfqvldgleea........ealkkfpklkalyervearpkika 94 
                  +++++++  l  +  +g++lvgdk+TyADl++ ++      +        + +k++p+ +++++++e+++++k+
  EEA20959.1 189 LRVISVIDLGLRrNpAAGNWLVGDKCTYADLSFATWALVGYGLlkelgkneGLEKDYPNYTQWIAKMEEQESVKK 263
                 3444455555557657778************98885433333335667555444******************997 PP

>> GST_C_2  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   3.9e-06      0.01       3      68 ..     180     253 ..     178     254 .. 0.82

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 3.9e-06
                 HHCHHHHHCCHCHHHCTTT---SS.....CTTCS--HHHHHHHH....HHHHHHHHHHS----TT-HHHHHHHH CS
     GST_C_2   3 averaleqldaaldaleahLadsp....flfGdqptlaDialap....flvrlraagpgfdireaypnlraWle 68 
                 a++r  +++ + +++++  L+  p    +l Gd+ t+aD ++a+     ++ l+  g ++ ++++ypn  +W++
  EEA20959.1 180 AIDRYINEILRVISVIDLGLRRNPaagnWLVGDKCTYADLSFATwalvGYGLLKELGKNEGLEKDYPNYTQWIA 253
                 68888899999999*******999999************88886322233344666888899**********86 PP

>> Tom37  Outer mitochondrial membrane transport complex protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       3.4   8.7e+03      91     120 ..      23      52 ..      20      56 .. 0.74
   2 ?   12.5   0.0   5.5e-05      0.14      17      68 ..      90     139 ..      76     159 .. 0.74

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 3.4
       Tom37  91 yslyvnsenyekvTrpayskllpfPlnyil 120
                  sl+ + +n  +  r+   + +++P ++++
  EEA20959.1  23 CSLFTSIDNSCTLLRSNIYSSFSIPNKLNM 52 
                 678888888888888888888888877765 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 5.5e-05
       Tom37  17 evvessnpslsptgeLPaLkdge.gtwisgfdnIveylrkkseesdldaslsa 68 
                 +v++ s  +++p+g+LPaL+d + g ++ +   I+ yl ++   +d d ++s 
  EEA20959.1  90 DVKTESYLEVTPNGRLPALRDPNtGITLWESGAIILYLVDQ---YDRDGKISY 139
                 5788888899***********985445599999*****988...444444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (279 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       419  (0.02337); expected 358.6 (0.02)
Passed bias filter:                      386  (0.0215294); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.41
# Mc/sec: 2064.17
//
Query:       EEA20960.1  [L=447]
Description: hypothetical protein PMAA_047720 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (447 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       399  (0.0222544); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.41
# Mc/sec: 3258.86
//
Query:       EEA20961.1  [L=151]
Description: 40S ribosomal protein S11 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.7e-46  156.0   1.0    4.6e-46  155.7   1.0    1.1  1  Ribosomal_S11  Ribosomal protein S11
  ------ inclusion threshold ------
      0.068   13.4   0.0       0.12   12.6   0.0    1.4  1  CBM_25         Carbohydrate binding domain (family 25)


Domain annotation for each model (and alignments):
>> Ribosomal_S11  Ribosomal protein S11
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  155.7   1.0   5.2e-50   4.6e-46       1     110 []      29     147 ..      29     147 .. 0.99

  Alignments for each domain:
  == domain 1  score: 155.7 bits;  conditional E-value: 5.2e-50
  Ribosomal_S11   1 GvahiqasfnntiititdlkGaevlvksaGglgvkasr.kssPyaaqlaaekaaekvldkGikavevkvkg........pGpGreaalralaraGl 87 
                    Gva+i+asfn+t++++tdl+G+e++ + +Gg++vka+r +ssPyaa+laa+++a ++++ Gi+a+++k+++        pGpG+++alralar+G+
     EEA20961.1  29 GVARIFASFNDTFVHVTDLSGRETICRVTGGMKVKADRdESSPYAAMLAAQDVAVRCKELGINALHIKIRAtggngtktPGPGAQSALRALARSGM 124
                    89********************************************************************************************** PP

  Ribosomal_S11  88 kigriedvtPiPhdgirrpkkrr 110
                    kigriedvtP+P d++rr+++rr
     EEA20961.1 125 KIGRIEDVTPTPSDSTRRKGGRR 147
                    ********************998 PP

>> CBM_25  Carbohydrate binding domain (family 25)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   1.3e-05      0.12      12      59 ..      85     132 ..      77     142 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.3e-05
      CBM_25  12 trkkGftsayihyrpaGGswtavpGvkmrdaeaGyakkdvdlGaassl 59 
                 ++++G ++ +i+ r +GG  t +pG + ++a    a+  + +G   ++
  EEA20961.1  85 CKELGINALHIKIRATGGNGTKTPGPGAQSALRALARSGMKIGRIEDV 132
                 5789***************************99999999999976665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (151 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       314  (0.0175135); expected 358.6 (0.02)
Passed bias filter:                      270  (0.0150594); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.44
# Mc/sec: 1039.34
//
Query:       EEA20962.1  [L=435]
Description: prephenate dehydrogenase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      1e-14   54.2   0.0    1.7e-14   53.4   0.0    1.3  1  PDH            Prephenate dehydrogenase
    8.3e-07   29.5   0.0    1.7e-06   28.5   0.0    1.5  1  F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
    3.4e-06   27.3   0.0    5.8e-06   26.6   0.0    1.4  1  NAD_binding_2  NAD binding domain of 6-phosphogluconate dehyd
    0.00013   21.6   0.0    0.00026   20.7   0.0    1.5  1  ApbA           Ketopantoate reductase PanE/ApbA
    0.00015   21.2   0.0    0.00025   20.5   0.0    1.3  1  2-Hacid_dh_C   D-isomer specific 2-hydroxyacid dehydrogenase,
     0.0018   18.2   0.0     0.0033   17.3   0.0    1.5  1  3HCDH_N        3-hydroxyacyl-CoA dehydrogenase, NAD binding d
  ------ inclusion threshold ------
      0.045   14.0   0.0        0.1   12.8   0.0    1.6  1  TrkA_N         TrkA-N domain
      0.091   12.8   0.0        0.2   11.7   0.0    1.5  1  Shikimate_DH   Shikimate / quinate 5-dehydrogenase
       0.17   11.7   0.0       0.33   10.8   0.0    1.4  1  Rossmann-like  Rossmann-like domain


Domain annotation for each model (and alignments):
>> PDH  Prephenate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.4   0.0   8.7e-18   1.7e-14      46     257 ..      68     272 ..      38     273 .. 0.93

  Alignments for each domain:
  == domain 1  score: 53.4 bits;  conditional E-value: 8.7e-18
                 GSEEEE-S-GGGHHHHHHHHHHHS-TT-EEEE--S--CHHHHHHHHHCC..GCEEEEEES---S-SSGGG--TTTTTT-EEEEEE-TTS-HHHHHHHHH CS
         PDH  46 adivvlavPvevilevlkelaphlkedalitDvgsvKekvvreleellkegksfvgghPmaGteksGvdaareelfenavviLtPtektdkealekvke 144
                  d ++ +v    i ++++e  p  k +a++  ++s K     + +++l++ +++++ h + G+         +   ++++ +L    ++d e +  + +
  EEA20962.1  68 SDYIIYSVEAAYIDKIVAEYGPSTKVGAIVGGQTSCKSPELAAFDKHLPSDVEIISCHSLHGP---------KVNTKGQPLVLIQHRASD-ESMRFIER 156
                 488999999999***************************************************.........55569**********999.9******* PP

                 HHHHCT-EEEE--HHHHHHHHHHHTHHHHHHHHHHHHHHHCHHCCCCHHHHCGTCCHHHHH....CGGGS-HHHHHHHHHHTHHHHHHHHHHHHHHHHH CS
         PDH 145 lleevgarvilmspeeHDrvvavvshlphvvaialaatlkekkndekeirklasggfrdvt....RiaksnPelwadilleNkeavlealdkfikelkk 239
                 ++e  + + +++s e HDr++a ++ ++h+++ ++  +   +++   ei ++ +g+ +  +    Ri ++   ++a +++ N    ++++ +++k++++
  EEA20962.1 157 VFESFESQYVYLSGEMHDRITADTQAVTHAAFLSMGTAWYSNNQFPWEIDRWVGGIENVKInitlRIYANKWHVYAGLAILNPA-AKKQIRQYAKSVTE 254
                 *************************************999***************9776666778*****************99.9************* PP

                 HHHHHHTT-HHHHHHHHH CS
         PDH 240 lkelienedaeeLvellk 257
                 l +l+ ++++eeL +  k
  EEA20962.1 255 LYKLMIEGKREELKKRVK 272
                 *************98776 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.5   0.0   8.4e-10   1.7e-06       2      89 ..      10      95 ..       9      97 .. 0.84

  Alignments for each domain:
  == domain 1  score: 28.5 bits;  conditional E-value: 8.4e-10
                   EEEETTSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC..-EEECECHHHHHH.H-SEEEE-S-HHHHHHHHHHCGHHHHTTS CS
  F420_oxidored  2 igiiGaGnmgealasgllaagaqpheivvansrnpekaeelaeelg..vkvtavdneeaae.eadvvvlavkpedveevlselakdalkgk 89
                   igiiG+G+mg+  a++l++ag     i  a++r+ +k e+l++e+     ++  +n  +++  +d ++ +v  ++++++++e  ++++ g 
     EEA20962.1 10 IGIIGMGDMGKMYAQRLSQAG---WRIN-ACDRS-DKYESLKQEYAsdKAISIFPNGHLVSrISDYIIYSVEAAYIDKIVAEYGPSTKVGA 95
                   9********************...9999.98887.569*******999555555677777759*****************99866666555 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.6   0.0   2.9e-09   5.8e-06       1      85 [.       9      96 ..       9     115 .. 0.76

  Alignments for each domain:
  == domain 1  score: 26.6 bits;  conditional E-value: 2.9e-09
                   EEEEE--SHHHHHHHHHHHHTT-EEEEE-SSHHHHHHHHHTT....EEE-SSHHHHHHHC.SEEEE-SSSHHHHHHHHHSHCCC--TT-E CS
  NAD_binding_2  1 kigfiGlGvMGsnmalnllkagykvavynrtkekveelvaeg....akaaesieelvasl.dvvitmvkagkavdeviegllealkkgdi 85
                   +ig+iG+G MG+  a++l +ag+++ + +r+ +k e+l +e     a  +     lv+++ d +i  v+a + +d+++ +  ++ k g+i
     EEA20962.1  9 SIGIIGMGDMGKMYAQRLSQAGWRINACDRS-DKYESLKQEYasdkAISIFPNGHLVSRIsDYIIYSVEA-AYIDKIVAEYGPSTKVGAI 96
                   59***************************99.77777777755555555555566777777999999987.5566666666666666655 PP

>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.7   0.0   1.3e-07   0.00026       1      39 [.      10      48 ..      10      64 .. 0.95

  Alignments for each domain:
  == domain 1  score: 20.7 bits;  conditional E-value: 1.3e-07
                EEEES-SHHHHHHHHHHHHHTHCEEEE-SCHHHHHHHHH CS
        ApbA  1 iailGaGaiGsllaakLakagadvtlilrsrrlealkkn 39
                i i+G+G +G ++a +L++ag+ +  ++rs+++e+lk++
  EEA20962.1 10 IGIIGMGDMGKMYAQRLSQAGWRINACDRSDKYESLKQE 48
                79*********************************9987 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5   0.0   1.2e-07   0.00025      36      77 ..       7      47 ..       2      72 .. 0.83

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 1.2e-07
                  TSEEEEES-SHHHHHHHHHHHHTT-EEEEESSSHHHHHCHHH CS
  2-Hacid_dh_C 36 gktvGiiGlGrIGqavakrlkafgmkviaydrskkkeeeeee 77
                  +  +GiiG+G++G+  a+rl++ g ++ a drs k e+  ++
    EEA20962.1  7 NASIGIIGMGDMGKMYAQRLSQAGWRINACDRSDKYES-LKQ 47
                  6789*****************************88666.333 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0   1.7e-06    0.0033       2      46 ..      10      54 ..       9     100 .. 0.84

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 1.7e-06
                EEEE--SCCHHHHHHHHHHTT-EEEEE-S-HHHHHHHHHHHHHHH CS
     3HCDH_N  2 vaviGaGtmGagiaavfasagleVvlvdiseealekalekieksl 46
                +++iG G mG+  a+ + +ag +++ +d+s++     +e ++++ 
  EEA20962.1 10 IGIIGMGDMGKMYAQRLSQAGWRINACDRSDKYESLKQEYASDKA 54
                89***************************9987776666666655 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   5.2e-05       0.1       3      40 ..      12      48 ..      10      56 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 5.2e-05
                EES-SHHHHHHHHHHHHTTEEEEEEESSHHHHHHHHHT CS
      TrkA_N  3 iiGlGrvGrslaeeLseggkdvvvidkdeerveelree 40
                iiG+G++G+  a++Ls++g+++ + d++ ++ e+l++e
  EEA20962.1 12 IIGMGDMGKMYAQRLSQAGWRINACDRS-DKYESLKQE 48
                9****************8888*999997.577777665 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0    0.0001       0.2      12      59 ..       7      52 ..       2      80 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.0001
                  T-EEEEES-SHHHHHHHHHHHCCT-CEEEEEESSHHHHHHHHHHHT.E CS
  Shikimate_DH 12 ekkvlliGaGemaelvakhLlakgvkkvvvaNRtlerakelaeelkge 59
                  ++ + +iG G m++  a+ L+++g + +    R+ ++ ++l +e+ ++
    EEA20962.1  7 NASIGIIGMGDMGKMYAQRLSQAGWR-INACDRS-DKYESLKQEYASD 52
                  67899********************9.9999997.6888888888444 PP

>> Rossmann-like  Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00017      0.33      11     100 ..       8      97 ..       4     106 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00017
  Rossmann-like  11 lsvGiisaGrvGtalgaaleraghvvvgisaisaasreraerrlPdvpvl..ev.edvaaraellllavPdaelpglvkglaatgavraGtiv 100
                     s+Gii+ G +G   ++ l +ag  + ++   s+  + + ++   d ++   +  + v + ++ ++ +v  a + ++v++   +  ++ G iv
     EEA20962.1   8 ASIGIIGMGDMGKMYAQRLSQAGWRINACDR-SDKYESLKQEYASDKAISifPNgHLVSRISDYIIYSVEAAYIDKIVAEYGPS--TKVGAIV 97 
                    589*************************975.5555555555555554431133134667799999999999999999988765..6667776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (435 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       536  (0.0298957); expected 358.6 (0.02)
Passed bias filter:                      480  (0.0267723); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.62u 0.31s 00:00:00.93 Elapsed: 00:00:00.50
# Mc/sec: 2627.02
//
Query:       EEA20963.1  [L=282]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    0.00055   20.1   0.2    0.00096   19.3   0.2    1.4  1  Podoplanin       Podoplanin
      0.001   18.4   0.9      0.002   17.5   0.9    1.5  1  SKG6             Transmembrane alpha-helix domain
     0.0018   17.8   0.2     0.0035   16.8   0.2    1.5  1  Rax2             Cortical protein marker for cell polarity
  ------ inclusion threshold ------
      0.062   13.3   0.0      0.097   12.7   0.0    1.3  1  Cytomega_TRL10   Cytomegalovirus TRL10 protein
      0.082   13.8   0.0       0.16   12.8   0.0    1.5  1  EphA2_TM         Ephrin type-A receptor 2 transmembrane domai
        0.1   12.5   1.2       0.26   11.2   1.2    1.7  1  TMEM154          TMEM154 protein family
        1.3    9.0   5.9        3.3    7.7   5.9    1.6  1  MSA-2c           Merozoite surface antigen 2c


Domain annotation for each model (and alignments):
>> Podoplanin  Podoplanin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.2   3.8e-07   0.00096      79     155 ..     142     219 ..      89     221 .. 0.75

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 3.8e-07
                 -GGG-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXX CS
  Podoplanin  79 rledlptaestvkakeesqstttlnvvtshstekvgeetettvekdGLatvtLvgiivGvll.aigfiggiiivvvrk 155
                      +t++ t++    s s++++ + t+ st  +  +t t+     L+t +  gi +G  + a+ +++gii+ ++r+
  EEA20963.1 142 TSTPGATSALTTASSALSTSASASPASTALSTTPTPTSTPTSPSTSSLSTGAKAGIGIGAAVgALLILAGIIFFIIRR 219
                 333345555666666777777788888999999999***********************988457788*******997 PP

>> SKG6  Transmembrane alpha-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   0.9   7.8e-07     0.002       1      38 []     184     221 ..     184     221 .. 0.93

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 7.8e-07
        SKG6   1 psdssnsntvaIavaVaVPVaViiivLlailifvrRRk 38 
                 ps ss+s+++  +++++  V++ +i+ ++i++++rRR+
  EEA20963.1 184 PSTSSLSTGAKAGIGIGAAVGALLILAGIIFFIIRRRR 221
                 788999***9999999999******************6 PP

>> Rax2  Cortical protein marker for cell polarity
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.2   1.4e-06    0.0035     154     204 ..     154     232 ..      97     237 .. 0.67

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 1.4e-06
        Rax2 154 k.............................kkkkklsrgfVVlIgLAlALgtvallgllgiilayirkkregyepakp.ri 204
                                                +++ ls+g+  +Ig + A+g  all l+gii+ +ir++r++    k+  +
  EEA20963.1 154 AssalstsasaspastalsttptptstptsPSTSSLSTGAKAGIGIGAAVG--ALLILAGIIFFIIRRRRNNAAANKQeNM 232
                 0333333333445556666666666666668999*****************..68999*************9776666444 PP

>> Cytomega_TRL10  Cytomegalovirus TRL10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   3.8e-05     0.097      53     111 ..     190     250 ..     140     277 .. 0.63

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 3.8e-05
  Cytomega_TRL10  53 vlgaysawgagsfvatlivll.vvffviyareeek.nntgtevdqclayrsltrkkleqha 111
                       ga +  g g+ v +l++l  ++ff+i  r +++  n+  ++d  l+  +l ++     a
      EEA20963.1 190 STGAKAGIGIGAAVGALLILAgIIFFIIRRRRNNAaANKQENMDMHLTPAQLQQQEYYVEA 250
                     25899999******99888863788888876665514566677888887777776655444 PP

>> EphA2_TM  Ephrin type-A receptor 2 transmembrane domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   6.4e-05      0.16       4      37 ..     200     240 ..     197     272 .. 0.53

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 6.4e-05
    EphA2_TM   4 aavaglvllvilvilvlvlvrrrsknrkqksdl.........k 37 
                 +a++g++l+++   ++++++rrr++n ++++++         +
  EEA20963.1 200 GAAVGALLILA--GIIFFIIRRRRNNAAANKQEnmdmhltpaQ 240
                 34444444444..444555556666666555543443332220 PP

>> TMEM154  TMEM154 protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   1.2    0.0001      0.26       8      94 ..     142     228 ..     134     246 .. 0.59

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.0001
     TMEM154   8 gdtaletatleeesadatsaasteseslkqeeakeslssaelsnesdqlel..vlmiiiPlvllillllvviiliqkkkrkrsKddeks 94 
                 ++t++ t  l++ s+ +++ as+ s++     +  +  s+ +s+  ++l+      i i + + +ll+l++ii+  + +r+r+    ++
  EEA20963.1 142 TSTPGATSALTTASSALSTSASA-SPASTALSTTPTPTSTPTSPSTSSLSTgaKAGIGIGAAVGALLILAGIIFF-IIRRRRNNAAANK 228
                 34444444444555554444444.333333334444455556666666655545668899999********9998.6677766544333 PP

>> MSA-2c  Merozoite surface antigen 2c
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   5.9    0.0013       3.3     151     205 ..     142     196 ..     121     204 .. 0.77

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0013
      MSA-2c 151 ekkPsrtssaetPaPsdaesaaaqPPeskpaqaPaPtspsqseesssnlqGqsag 205
                   +P  ts   t + + + sa+a P  +  + +P+Pts + s+ +ss   G +ag
  EEA20963.1 142 TSTPGATSALTTASSALSTSASASPASTALSTTPTPTSTPTSPSTSSLSTGAKAG 196
                 4578888888888888888888888777889999998888877777666666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (282 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1012  (0.0564449); expected 358.6 (0.02)
Passed bias filter:                      574  (0.0320152); expected 358.6 (0.02)
Passed Vit filter:                        86  (0.0047967); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 1953.22
//
Query:       EEA20964.1  [L=303]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    0.00057   20.0   0.2    0.00096   19.3   0.2    1.4  1  Podoplanin  Podoplanin
    0.00091   18.6   0.9     0.0022   17.3   0.9    1.7  1  SKG6        Transmembrane alpha-helix domain
     0.0021   17.5   0.1      0.004   16.6   0.1    1.5  1  Rax2        Cortical protein marker for cell polarity
  ------ inclusion threshold ------
      0.054   13.4   0.1       0.14   12.0   0.1    1.7  1  TMEM154     TMEM154 protein family
      0.086   13.7   0.0       0.19   12.6   0.0    1.5  1  EphA2_TM    Ephrin type-A receptor 2 transmembrane domain
        1.8    8.5   5.9        3.7    7.5   5.9    1.5  1  MSA-2c      Merozoite surface antigen 2c


Domain annotation for each model (and alignments):
>> Podoplanin  Podoplanin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.2   3.2e-07   0.00096      78     155 ..     162     240 ..      88     242 .. 0.77

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 3.2e-07
                 --GGG-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXX CS
  Podoplanin  78 lrledlptaestvkakeesqstttlnvvtshstekvgeetettvekdGLatvtLvgiivGvll.aigfiggiiivvvrk 155
                 +     +t++ t++    s s++++ + t+ st  +  +t t+     L+t +  gi +G  + a+ +++gii+ ++r+
  EEA20964.1 162 DTSTPGATSALTTASSALSTSASASPASTALSTTPTPTSTPTSPSTSSLSTGAKAGIGIGAAVgALLILAGIIFFIIRR 240
                 3333445555666666777777778888999999999***********************988457788*******997 PP

>> SKG6  Transmembrane alpha-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.9   7.4e-07    0.0022       1      38 []     205     242 ..     205     242 .. 0.93

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 7.4e-07
        SKG6   1 psdssnsntvaIavaVaVPVaViiivLlailifvrRRk 38 
                 ps ss+s+++  +++++  V++ +i+ ++i++++rRR+
  EEA20964.1 205 PSTSSLSTGAKAGIGIGAAVGALLILAGIIFFIIRRRR 242
                 788999***9999999999******************6 PP

>> Rax2  Cortical protein marker for cell polarity
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.1   1.3e-06     0.004     154     204 ..     175     253 ..     118     258 .. 0.67

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 1.3e-06
        Rax2 154 k.............................kkkkklsrgfVVlIgLAlALgtvallgllgiilayirkkregyepakp.ri 204
                                                +++ ls+g+  +Ig + A+g  all l+gii+ +ir++r++    k+  +
  EEA20964.1 175 AssalstsasaspastalsttptptstptsPSTSSLSTGAKAGIGIGAAVG--ALLILAGIIFFIIRRRRNNAAANKQeNM 253
                 0333333333345555666666666666668999*****************..68999*************9776665444 PP

>> TMEM154  TMEM154 protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.1   4.8e-05      0.14       8      94 ..     163     249 ..     155     267 .. 0.59

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 4.8e-05
     TMEM154   8 gdtaletatleeesadatsaasteseslkqeeakeslssaelsnesdqlel..vlmiiiPlvllillllvviiliqkkkrkrsKddeks 94 
                 ++t++ t  l++ s+ +++ as+ s++     +  +  s+ +s+  ++l+      i i + + +ll+l++ii+  + +r+r+    ++
  EEA20964.1 163 TSTPGATSALTTASSALSTSASA-SPASTALSTTPTPTSTPTSPSTSSLSTgaKAGIGIGAAVGALLILAGIIFF-IIRRRRNNAAANK 249
                 34444444444555554444444.333333334444455556666666655545668899999********9998.6677666544333 PP

>> EphA2_TM  Ephrin type-A receptor 2 transmembrane domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   6.4e-05      0.19       4      37 ..     221     261 ..     218     292 .. 0.53

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 6.4e-05
    EphA2_TM   4 aavaglvllvilvilvlvlvrrrsknrkqksdl.........k 37 
                 +a++g++l+++   ++++++rrr++n ++++++         +
  EEA20964.1 221 GAAVGALLILA--GIIFFIIRRRRNNAAANKQEnmdmhltpaQ 261
                 34444444444..444555556666665555543433332220 PP

>> MSA-2c  Merozoite surface antigen 2c
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   5.9    0.0012       3.7     151     205 ..     163     217 ..     142     225 .. 0.77

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0012
      MSA-2c 151 ekkPsrtssaetPaPsdaesaaaqPPeskpaqaPaPtspsqseesssnlqGqsag 205
                   +P  ts   t + + + sa+a P  +  + +P+Pts + s+ +ss   G +ag
  EEA20964.1 163 TSTPGATSALTTASSALSTSASASPASTALSTTPTPTSTPTSPSTSSLSTGAKAG 217
                 4578888888888888888888888777889999998888877777666666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (303 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1092  (0.0609069); expected 358.6 (0.02)
Passed bias filter:                      601  (0.0335211); expected 358.6 (0.02)
Passed Vit filter:                        87  (0.00485247); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.46
# Mc/sec: 1963.34
//
Query:       EEA20965.1  [L=500]
Description: catalase Cat [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   6.2e-196  651.0   0.2   8.1e-196  650.6   0.2    1.1  1  Catalase      Catalase
    1.6e-09   37.8   0.0    4.6e-09   36.3   0.0    1.8  1  Catalase-rel  Catalase-related immune-responsive
  ------ inclusion threshold ------
       0.14   12.3   0.3       0.85    9.7   0.0    2.4  4  DUF3974       Domain of unknown function (DUF3974)


Domain annotation for each model (and alignments):
>> Catalase  Catalase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  650.6   0.2  1.4e-199  8.1e-196       1     379 [.      19     397 ..      19     400 .. 0.99

  Alignments for each domain:
  == domain 1  score: 650.6 bits;  conditional E-value: 1.4e-199
                 B-TTS-B-S-SSS-EEESTTS-BBTT-HHHHHHHHHHHT------SS--SEEEEEEEEEESS--TTT---GGGSSTT-EEEEEEEEE-SS--TT--SSS CS
    Catalase   1 ttseGapvsdnqnsltagerGplllqdvhlieklahfdreripeRvvhAkGagahgeFevtkdisdltkakllskvgkktpvlvRfStvagekgsadta 99 
                 tts+G+pv d+++s+++g++Gplllqd+hli+ lahfdreripeRvvhAkGaga+geFevt+disd+t++++l+ vgkkt++++RfStv+gekgsad+a
  EEA20965.1  19 TTSNGCPVFDPESSQRIGKNGPLLLQDFHLIDLLAHFDRERIPERVVHAKGAGAYGEFEVTDDISDITTIDMLKGVGKKTKLVTRFSTVGGEKGSADSA 117
                 89************************************************************************************************* PP

                 SS--EEEEEEEETTEEEEEEEESSSS-S-S-GGGHHHHHHHHSB-TTT-SB-HHHHHHHHHT-GGGHHHHHHHHSGGGSBS-GGGS-EE--S-EEEE-T CS
    Catalase 100 RdvrGfavkfyTeeGnwDlvgnntpvFfirDpikfpdlihsqkrepqtnlkdaamfwdflslnpeslhqvlilfsdrgipksyrhmngygvhtfklvnk 198
                 Rd+rGf+vkfyTe+GnwD+v+nntpvFf+rDp kfp +ih+qkr+pqtnlkda+mfwd+ls+++es+hqv++lfsdrg+p syrhmngy++htfk+++ 
  EEA20965.1 118 RDPRGFSVKFYTEQGNWDWVFNNTPVFFLRDPSKFPVFIHTQKRNPQTNLKDANMFWDYLSTHQESAHQVMHLFSDRGTPYSYRHMNGYSGHTFKWIKP 216
                 *************************************************************************************************** PP

                 T--EEEEEEEEEETT---B--HHHHHHHHHH-TTHHHHHHHHHHHTT---EEEEEEEEEEHHHHTTTHHHHT-TT----TTTS--EEEEEEEEEE--S- CS
    Catalase 199 egevvyvkfhfktkqgvknltaeeaeklagedpdyatrdLyeaiekgeypewelyvqvmteeeaeklrfnilDlTkvwpekevplrevGkltLnrnpen 297
                 +g++ yv++h+kt+qg k+lt+eea +l++++pd++t+dL++aie+geyp+w++yvq++++e+aek+r+n++DlTkvwp++evplr++G++tLn+npen
  EEA20965.1 217 DGTFNYVQIHLKTDQGNKTLTNEEAGELSNSNPDWHTQDLFQAIERGEYPSWTCYVQTLSPEQAEKFRWNVFDLTKVWPQSEVPLRRFGRFTLNKNPEN 315
                 *************************************************************************************************** PP

                 HHHHTTT----TT---TTEE--S-HHHHHHHHHHHHHHHHHT-TTGGGSGGG---..---S----TT-.....S-S---SS- CS
    Catalase 298 yFaevEqvafspsnlvpGiepseDklLqgRlfsYadtqryRlGvnyqqlpvNrpkakvanyqrdGamrveankgkepnYepn 379
                 yFae+Eq+af+ps+lvpG+eps+D++Lq+RlfsY+dt+r+RlGvnyqq+pvN+p +++++yqrdGam+v+ n+g++p Y ++
  EEA20965.1 316 YFAEIEQAAFAPSHLVPGVEPSADPVLQARLFSYPDTHRHRLGVNYQQIPVNCPLHAFNPYQRDGAMAVNGNYGANPAYPSS 397
                 ******************************************************99**********************9765 PP

>> Catalase-rel  Catalase-related immune-responsive
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.3   0.0   7.8e-13   4.6e-09       5      64 ..     428     488 ..     425     489 .. 0.95

  Alignments for each domain:
  == domain 1  score: 36.3 bits;  conditional E-value: 7.8e-13
                   --SSHHHHHHHHHS..-HHHHHHHHHHHHHHHTTSS-HHHHHHHHHHHHHH-HHHHHHHHHH CS
  Catalase-rel   5 ddhfsQagllyrsm..seeekerlvnniafelskvedeeiqerqlehfakvDpdlgqrVaea 64 
                   d++f Qa +l+r++  ++ ++e++v+n++ +l +++ e ++++    f+++++ lg+r+++a
    EEA20965.1 428 DEDFVQANALWRVLgrTPGQQENFVKNVSVHLCNAN-ERVRKQTYGFFTRINAILGERIKKA 488
                   79**********987799*****************8.**********************997 PP

>> DUF3974  Domain of unknown function (DUF3974)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0      0.67     4e+03      12      33 ..      39      60 ..      38      67 .. 0.87
   2 ?   -2.5   0.0      0.89   5.3e+03      55      78 ..     143     166 ..     138     195 .. 0.66
   3 ?   -3.1   0.0       1.3     8e+03      42      75 ..     183     218 ..     165     221 .. 0.62
   4 ?    9.7   0.0   0.00014      0.85      51     102 ..     420     475 ..     399     496 .. 0.74

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.67
     DUF3974 12 gillligltvvvllvyfgrkly 33
                g lll  + ++ ll +f r ++
  EEA20965.1 39 GPLLLQDFHLIDLLAHFDRERI 60
                66899999*********99875 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.89
     DUF3974  55 tpflkeftkhplfyrwirtegkke 78 
                 + fl++ +k p+f    + + + +
  EEA20965.1 143 VFFLRDPSKFPVFIHTQKRNPQTN 166
                 568889999999876655554444 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 1.3
     DUF3974  42 rahesieklsnkstpflkeftk..hplfyrwirteg 75 
                  ah+ ++ +s++ tp+     +      ++wi+ +g
  EEA20965.1 183 SAHQVMHLFSDRGTPYSYRHMNgySGHTFKWIKPDG 218
                 466677777777777743332211223466666655 PP

  == domain 4  score: 9.7 bits;  conditional E-value: 0.00014
     DUF3974  51 snkstpflke.ftkhplfyrwi.rtegkkeq..kvlnvlfcaanertreqvfsalp 102
                   + +p  +e f +   ++r + rt g++e+  k ++v +c aner r+q +  + 
  EEA20965.1 420 ISQQIPVTDEdFVQANALWRVLgRTPGQQENfvKNVSVHLCNANERVRKQTYGFFT 475
                 556667665439999888886559******8335567889**********987665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (500 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       491  (0.0273858); expected 358.6 (0.02)
Passed bias filter:                      430  (0.0239835); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 3416.43
//
Query:       EEA20966.1  [L=295]
Description: enoyl-CoA hydratase/isomerase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.3e-77  258.8   0.0      5e-77  258.6   0.0    1.0  1  ECH_1          Enoyl-CoA hydratase/isomerase
      9e-37  127.3   0.1    6.6e-36  124.5   0.1    1.9  1  ECH_2          Enoyl-CoA hydratase/isomerase
  ------ inclusion threshold ------
      0.058   14.1   0.0        0.1   13.4   0.0    1.5  1  TetR_C_33      Tetracyclin repressor-like, C-terminal domain
      0.099   12.6   0.0       0.21   11.5   0.0    1.5  1  Peptidase_S49  Peptidase family S49


Domain annotation for each model (and alignments):
>> ECH_1  Enoyl-CoA hydratase/isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  258.6   0.0   1.1e-80     5e-77       4     250 ..      47     294 ..      44     295 .] 0.97

  Alignments for each domain:
  == domain 1  score: 258.6 bits;  conditional E-value: 1.1e-80
                 TTEEEEEE--CGCTTEE-HHHHHHHHHHHHHHHHSTTECEEEEEEBTSEEEEEB-HHHHHHHHCHHHHHHHCCHHHHHHHHHH.SSSEEEEEE-SEEET CS
       ECH_1   4 agvaviklnrPeavNalsaelltEliqalekleddksvravvLtGgdkaFaaGadlkemaeeekakqallkeevlelwtklyt.vpkpviaavnGaaig 101
                  gv +i+lnrP+a+Nals  l +El++al k ++dk ++a+++tG++kaFaaGad+kema     + a +++++ + w++l + + kpviaav+G+a+g
  EEA20966.1  47 PGVGLITLNRPKALNALSSPLFQELNDALSKYDQDKDIGAIIITGSEKAFAAGADIKEMAPL--TFSAAYSNNFIAPWSHLANsIRKPVIAAVSGYALG 143
                 5899*********************************************************7..8**************9975279************* PP

                 HHHHHHHHSSEEEEETTTEEE-GGGGGTS--CTTCHHHHHHHHHHHHHHHHHHHT-EEEHHHHHHCTSSSEEESG..GGHHHHHHHHHHHHHHSCHHHH CS
       ECH_1 102 GGlelalacDiviaadnasfglnelklGlipgaggtqilarkvGkskAeeilllgkkisaqealkvGlvdkvvpe..eqlleealelaeklaekspaal 198
                 GG+elal+cDi+++  na fg++e+klG+ipgagg+q+l+r++Gks+A+e++l+gk++s++ea ++G+  +v+    e+ll e l+ ae +a  s+ a+
  EEA20966.1 144 GGCELALMCDIIYCTSNATFGQPEIKLGVIPGAGGSQRLTRAIGKSRAMELILTGKNFSGKEAGEWGVAARVIDGgkEELLAEVLKTAETIAGYSRVAV 242
                 ************************************************************************96555********************** PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTSHHHHHHHHHHHTCSH----- CS
       ECH_1 199 rqlkealnakledalaeqleaeaklfestfskddikeGlqaflEkrkpefed 250
                 +++ke +n+  e  l e++e e++lf+ +f ++d k G++af+Ek+k+e++ 
  EEA20966.1 243 VAAKEVVNKSQELSLREGVEYERRLFHGLFGSKDQKIGMTAFAEKKKAEWTH 294
                 **************************************************85 PP

>> ECH_2  Enoyl-CoA hydratase/isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  124.5   0.1   1.5e-39   6.6e-36       1     239 [.      49     285 ..      49     295 .] 0.83

  Alignments for each domain:
  == domain 1  score: 124.5 bits;  conditional E-value: 1.5e-39
                 .EEEEE--GGGTT-B-HHHHHHHHHHHHHHCC-TT-SEEEEEESSSSECE--B--HHHHHHHHCS-THHHHHHHHHHHHHHHHHC-SS-EEEEE-BEEE CS
       ECH_2   1 vgvitLnrpkalNaLslemvralkealkewekddevklvvlkgagekafCAGgDvralyeaakegkkeeeeffreeYklnyliatypkpvvalmdGivm 99 
                 vg+itLnrpkalNaLs +++++l++al+++++d+++ +++++g +ekaf AG D+++++    + + + ++f++      +l ++++kpv+a + G+++
  EEA20966.1  49 VGLITLNRPKALNALSSPLFQELNDALSKYDQDKDIGAIIITG-SEKAFAAGADIKEMAPLTFSAAYS-NNFIAP---WSHLANSIRKPVIAAVSGYAL 142
                 589****************************************.66**************99998777.567765...467778889************ PP

                 THHHHHHTTSSEEEE-TT-EEE--GGGGT----TTHHHHHHCSST.THHHHHHHH---B-HHHHHHTTS--EE--GGGHHHHHHHHHTT.........- CS
       ECH_2 100 GgGvGlsvhgsfrvvtertvfAmPEtaIGlfPDvGgsyfLsrlpg.elGlylalTGarlkgadalaaglathyvpseklealeeaLaelessd.eeave 196
                 GgG+ l++ + +   t +++f  PE+++G++P  Ggs  L+r+ g + ++ l lTG++++g++a + g+a  +++  k e l+e L+++e+ +  ++v+
  EEA20966.1 143 GGGCELALMCDIIYCTSNATFGQPEIKLGVIPGAGGSQRLTRAIGkSRAMELILTGKNFSGKEAGEWGVAARVIDGGKEELLAEVLKTAETIAgYSRVA 241
                 ******************************************97647799************************************9998776645554 PP

                 -------......--.--SHHHHHHHHHHHT.-S-TTTHHHHHH CS
       ECH_2 197 evleelaeeaeeeee.eselaekreaidrlfsadsveeiveaLe 239
                  v+++   ++++e + ++ ++ +r+  + lf++++ +  ++a +
  EEA20966.1 242 VVAAKEVVNKSQELSlREGVEYERRLFHGLFGSKDQKIGMTAFA 285
                 44444333333333344555556666677776665555555554 PP

>> TetR_C_33  Tetracyclin repressor-like, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   2.3e-05       0.1       7      58 ..      25      82 ..      22     138 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 2.3e-05
                HHHHHHHH-HHHHHHCC.SS--T..T-S-.....HGHHCCCCHHHHHHHHHHHGGG---T CS
   TetR_C_33  7 ayrrfAlahpaeYallf.gspvp..gyaa.....pdelaaagarvlalllaalaalvaag 58
                 yrrf  + pa Y+ +  ++p p  g        p++l a ++++++ l +al+++ +++
  EEA20966.1 25 SYRRFSTTSPASYEYILtETPKPgvG--LitlnrPKALNALSSPLFQELNDALSKYDQDK 82
                6**************99889998552..33354479******************993333 PP

>> Peptidase_S49  Peptidase family S49
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   4.7e-05      0.21       4      40 ..     128     164 ..     126     172 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 4.7e-05
                    HTT--EEEEEEEEEETHHHHHHTTSSEEEE-TT-EEE CS
  Peptidase_S49   4 kakkPvvasaenvaaSggYylasaadkivanpstivg 40 
                    +  kPv+a ++++a  gg  la ++d i+ ++++  g
     EEA20966.1 128 SIRKPVIAAVSGYALGGGCELALMCDIIYCTSNATFG 164
                    678****************************999766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (295 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       382  (0.0213063); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.47
# Mc/sec: 1896.34
//
Query:       EEA20967.1  [L=189]
Description: Golgi membrane protein (Rer1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-80  269.5   5.2    1.2e-80  269.2   5.2    1.0  1  Rer1      Rer1 family
  ------ inclusion threshold ------
       0.16   12.0   2.7        5.2    7.2   0.2    2.2  2  DUF962    Protein of unknown function (DUF962)


Domain annotation for each model (and alignments):
>> Rer1  Rer1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  269.2   5.2   1.3e-84   1.2e-80       2     171 .]      17     187 ..      16     187 .. 0.97

  Alignments for each domain:
  == domain 1  score: 269.2 bits;  conditional E-value: 1.3e-84
        Rer1   2 alkklkrkyqklldkltpytleRWiatlvllllfllriillqgfyivaYalgiylLnlllafltPkfdpsleeeaaeeeaeega.elptkkdeefrPfi 99 
                 +++kl+r+yq++ld+ltpyt++RWi+ +vlll+f+lri+l+qg+yivaY+lgiylLnl+lafl+Pkfdpsl++++  e+ e+g+ +lp k+d+efrPfi
  EEA20967.1  17 QTSKLARQYQAYLDQLTPYTAYRWIGSVVLLLFFFLRIVLAQGWYIVAYTLGIYLLNLFLAFLSPKFDPSLTQDEGLEDGEAGSsSLPIKQDDEFRPFI 115
                 57899********************************************************************8888888887769************* PP

        Rer1 100 rrlpEfkfWlsatkailialvltffevfdvpVfwpiLlvyfivlfvltmrrqikhmikykyvpfdlgKkkyk 171
                 rrlpEfkfW+sat+ai+i++v+++f+vfd+pVfwp+L++y+++lf+ltmrrqi+hmiky+y+pf++gK++y+
  EEA20967.1 116 RRLPEFKFWHSATRAIAISFVCSWFKVFDIPVFWPVLVMYWLILFFLTMRRQIQHMIKYRYIPFNIGKTRYG 187
                 **********************************************************************95 PP

>> DUF962  Protein of unknown function (DUF962)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.2    0.0026        23       3      59 ..      20      74 ..      18      90 .. 0.74
   2 ?    7.2   0.2   0.00058       5.2       2      51 ..     112     161 ..     111     169 .. 0.79

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0026
      DUF962  3 sleefyafYlaeHsnpinrllHfigvplilltvlllllraklklllalfvvgyifaf 59
                +l+++y+ Yl++ +  +     +ig++++ll+++l ++ a+ ++++a  +  y +  
  EEA20967.1 20 KLARQYQAYLDQLTPYTA--YRWIGSVVLLLFFFLRIVLAQGWYIVAYTLGIYLLNL 74
                567778888877655544..4589999999999999999999998888888777655 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.00058
      DUF962   2 ksleefyafYlaeHsnpinrllHfigvplilltvlllllraklklllalf 51 
                 + + + ++ ++  Hs ++ +++ f+++++ ++ + ++     + +l++ f
  EEA20967.1 112 RPFIRRLPEFKFWHSATRAIAISFVCSWFKVFDIPVFWPVLVMYWLILFF 161
                 5677889999999*****************99888776655555555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (189 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       799  (0.0445647); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1253.97
//
Query:       EEA20968.1  [L=210]
Description: Golgi membrane protein (Rer1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-64  216.3   5.3      3e-64  215.9   5.3    1.1  1  Rer1      Rer1 family
  ------ inclusion threshold ------
       0.17   12.0   2.4        5.8    7.1   0.1    2.3  2  DUF962    Protein of unknown function (DUF962)


Domain annotation for each model (and alignments):
>> Rer1  Rer1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  215.9   5.3   3.4e-68     3e-64       2     147 ..      17     163 ..      16     166 .. 0.96

  Alignments for each domain:
  == domain 1  score: 215.9 bits;  conditional E-value: 3.4e-68
        Rer1   2 alkklkrkyqklldkltpytleRWiatlvllllfllriillqgfyivaYalgiylLnlllafltPkfdpsleeeaaeeeaeega.elptkkdeefrPfi 99 
                 +++kl+r+yq++ld+ltpyt++RWi+ +vlll+f+lri+l+qg+yivaY+lgiylLnl+lafl+Pkfdpsl++++  e+ e+g+ +lp k+d+efrPfi
  EEA20968.1  17 QTSKLARQYQAYLDQLTPYTAYRWIGSVVLLLFFFLRIVLAQGWYIVAYTLGIYLLNLFLAFLSPKFDPSLTQDEGLEDGEAGSsSLPIKQDDEFRPFI 115
                 57899********************************************************************8888888887769************* PP

        Rer1 100 rrlpEfkfWlsatkailialvltffevfdvpVfwpiLlvyfivlfvlt 147
                 rrlpEfkfW+sat+ai+i++v+++f+vfd+pVfwp+L++y+++lf+lt
  EEA20968.1 116 RRLPEFKFWHSATRAIAISFVCSWFKVFDIPVFWPVLVMYWLILFFLT 163
                 **********************************************98 PP

>> DUF962  Protein of unknown function (DUF962)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.2    0.0032        28       3      59 ..      20      74 ..      18      90 .. 0.74
   2 ?    7.1   0.1   0.00065       5.8       2      51 ..     112     161 ..     111     170 .. 0.79

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.0032
      DUF962  3 sleefyafYlaeHsnpinrllHfigvplilltvlllllraklklllalfvvgyifaf 59
                +l+++y+ Yl++ +  +     +ig++++ll+++l ++ a+ ++++a  +  y +  
  EEA20968.1 20 KLARQYQAYLDQLTPYTA--YRWIGSVVLLLFFFLRIVLAQGWYIVAYTLGIYLLNL 74
                567778888877655544..4589999999999999999999998888887777655 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.00065
      DUF962   2 ksleefyafYlaeHsnpinrllHfigvplilltvlllllraklklllalf 51 
                 + + + ++ ++  Hs ++ +++ f+++++ ++ + ++     + +l++ f
  EEA20968.1 112 RPFIRRLPEFKFWHSATRAIAISFVCSWFKVFDIPVFWPVLVMYWLILFF 161
                 5677889999999*****************99888776655555555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (210 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       847  (0.0472419); expected 358.6 (0.02)
Passed bias filter:                      455  (0.0253779); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1420.97
//
Query:       EEA20969.1  [L=745]
Description: chromatin remodeling complex subunit (Arp8), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      2e-28   99.1   0.0    5.2e-18   64.8   0.0    2.6  2  Actin        Actin
      6e-07   28.6   0.0     0.0012   17.8   0.0    2.2  2  MreB_Mbl     MreB/Mbl protein
     0.0003   20.1   0.4      0.032   13.4   0.1    2.2  2  Actin_micro  Putative actin-like family
  ------ inclusion threshold ------
       0.02   15.3   0.0       0.11   12.9   0.0    2.3  2  FtsA         Cell division protein FtsA
       0.14   10.6   0.1        0.2   10.1   0.1    1.1  1  DUF2114      Uncharacterized protein conserved in archaea (DU
        3.2    6.9   7.6        5.3    6.2   7.6    1.3  1  DUF4106      Protein of unknown function (DUF4106)


Domain annotation for each model (and alignments):
>> Actin  Actin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.8   0.0   1.8e-21   5.2e-18       4     189 ..     105     398 ..     102     433 .. 0.86
   2 !   31.5   0.0   2.3e-11   6.9e-08     309     406 ..     642     741 ..     615     742 .. 0.84

  Alignments for each domain:
  == domain 1  score: 64.8 bits;  conditional E-value: 1.8e-21
       Actin   4 vsavVlDnGssttraGyagedaPkavipslvgkprgrkvea.......................................................... 44 
                 ++++Vl +Gs+++r+G a++  Pk+v p ++++++ +++++                                                          
  EEA20969.1 105 SKVIVLHVGSQNLRIGLASDALPKTV-PMVIARKSTKNESEdgveprpkrvklnedeteedtppekrfgpefaslyttmsaelkthmrqnkrrmlpnsk 202
                 689********************975.899998777765557********************************************************* PP

       Actin  45 ..................................klyvgdealt....krpelevrspvedGvvedwdavee.........lwehvlkeelkvdp.... 92 
                                                   ++  g+eal+    ++p ++++ p+++G+ ++ d +++         ++e ++k +l  ++    
  EEA20969.1 203 emvinynrrtvpehipehndpsrvewtefsnpppEYITGQEALRipddSKPRYKLSWPIRNGWCNEKDYANArlmfldialILEDAIKTQLGLTSkkdw 301
                 *****************************************7666443499****************97764333333333667777777655534444 PP

       Actin  93 eehpllltepplnppkqrekalEivfEkfkvpalylaksavlsafasgkstglvvDsGasvtsvvpVldGyvLkkairrsdlgGkaLteqlkellss 189
                  +++ +++ p l  ++  + +lE+++ +f ++ +++ ++   +af +g +t ++vD+Ga++ts++ V +G+ ++++  +++ gG ++te + +++ +
  EEA20969.1 302 PQYSCVFVIPDLYEKSYVTTILEMLMKEFSFARVCFIQESLAAAFGAGYTTTCIVDIGAQKTSICCVEEGMCVENSRINLKYGGFDVTETFIKMMLY 398
                 456667777889999999************************************************************************9999876 PP

  == domain 2  score: 31.5 bits;  conditional E-value: 2.3e-11
       Actin 309 ivaainacdvdlrpeLlanivvtGGnsllpglteRlekelaqlaskgv.kvkiiapee..erkysaWiGGSiLAslgtfqqlwvskqEYeEqGssvver 404
                 i++a    d ++ +++l  i v+GG s ++g+   le+ l  l ++   ++ i +p+   + +  +W G+S++++l+  ++ w+ + EY+  Gs++   
  EEA20969.1 642 ITHAARSDDKKM-RDFLGGIMVVGGGSQINGFHAYLEERLHLLRPAFAkEIMIGSPPRdlDAQVVVWKGASVFGKLDGTNDSWIGQLEYDRLGSRLLVY 739
                 444444444454.5799***********************99755433478888888889***********************************9999 PP

       Actin 405 kc 406
                 kc
  EEA20969.1 740 KC 741
                 98 PP

>> MreB_Mbl  MreB/Mbl protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   3.9e-07    0.0012      95     188 ..     305     396 ..     280     428 .. 0.78
   2 !    8.5   0.0   0.00026      0.78     276     299 ..     659     682 ..     653     690 .. 0.92

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 3.9e-07
                 EEEEEE-SS--HHHHHHHHHH.HHHTT-SEEEEEEHHHHHHHHTT--TTSSS-EEEEEE-SS-EEEEEEETTEEEEEEEE..S-SHHHHHHHHHHHH CS
    MreB_Mbl  95 rvvicvPsgiteverrAvkea.akkaGarevllieeplaAAiGaglpveepsgnmvvdiGggttevavislggivtsksv..rvaGdeldeaiikyi 188
                 + v  +P   ++     + e+ +k+    +v  i+e+laAA Gag      + + +vdiG+ +t++  +  g  v+ +++  + +G ++ e+ ik +
  EEA20969.1 305 SCVFVIPDLYEKSYVTTILEMlMKEFSFARVCFIQESLAAAFGAGY-----TTTCIVDIGAQKTSICCVEEGMCVENSRInlKYGGFDVTETFIKMM 396
                 555555555555555555554145566789***************7.....6789********************9998733568888877777765 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00026
                 -EEEESGGGGSBTHHHHHHHHHSS CS
    MreB_Mbl 276 givltGGgallkgldkllseetgl 299
                 gi+++GGg++++g++ +l+e+++l
  EEA20969.1 659 GIMVVGGGSQINGFHAYLEERLHL 682
                 9******************99886 PP

>> Actin_micro  Putative actin-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.1   1.1e-05     0.032     122     191 ..     307     376 ..     278     395 .. 0.86
   2 !    4.6   0.0     0.005        15     327     365 ..     703     741 ..     688     744 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 1.1e-05
  Actin_micro 122 slvfkdtlnrseilalvdlflnisgfkGilllPesLalclglgiqsaiviseyekhttvslveDyvllds 191
                   +v +d++++s + ++ +++++  +f  +    esLa ++g g   + +++   ++t ++ ve  + ++ 
   EEA20969.1 307 VFVIPDLYEKSYVTTILEMLMKEFSFARVCFIQESLAAAFGAGYTTTCIVDIGAQKTSICCVEEGMCVEN 376
                  5899**************************999**********998888888888899**9998776664 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.005
  Actin_micro 327 essilrgakvlkelevsKelWlTDkEWnsvrlRvLKeKv 365
                  + ++++ga v+ +l+ + + W+   E++  + R+L  K 
   EEA20969.1 703 QVVVWKGASVFGKLDGTNDSWIGQLEYDRLGSRLLVYKC 741
                  4689*************************9999997665 PP

>> FtsA  Cell division protein FtsA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0      0.81   2.4e+03      45      71 ..      92     146 ..      83     336 .. 0.63
   2 ?   12.9   0.0   3.8e-05      0.11       1      84 [.     354     678 ..     354     700 .. 0.62

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.81
                 HHHHHHHHH.HH--S--EEEEEHHHHH...........................G CS
                 xxxxxxxxx.xxxxxxxxxxxxxxxxx...........................x RF
        FtsA  45 veeAeriki.kyGsalaekeigrkels...........................g 71 
                 +e+Ae+++  + Gs +   ++g+++l                            g
  EEA20969.1  92 MEDAEEVEAeTAGSKVIVLHVGSQNLRiglasdalpktvpmviarkstknesedG 146
                 6666666631233333322222222223333333333333333333333333340 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 3.8e-05
                 EEEEE-SSSEEEEEEETTEEEEEEEES-..-HHHHHHH..............HHHHHT--HHHHHHHHHHH--S--...........EEEEEHHHHH.. CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxx..............xxxxxxxxxxxxxxxxxxxxxxxx...........xxxxxxxxxx.. RF
        FtsA   1 alvDiGagktdvavaedgalvhlrvigv..ggngitkd..............iakalrtaveeAerikikyGsala...........ekeigrkels.. 70 
                 ++vDiGa+kt++  +e+g  v  + i++  gg  +t+               i    r  +  Ae +k++  + ++           +           
  EEA20969.1 354 CIVDIGAQKTSICCVEEGMCVENSRINLkyGGFDVTETfikmmlydhfpyadINLNRRYDFLLAEDLKKN-VCTMNesgvsvqvfdfH--------Lrv 443
                 68******************99999988889999999998888888888766666667888888888843.33333233333344441........034 PP

                 ................................................................................................... CS
                 ................................................................................................... RF
        FtsA  71 ................................................................................................... 70 
                                                                                                                    
  EEA20969.1 444 sgqdtrkytfkaydevylapmgyfqpgifsvgdklqgrrklfprsydiydgqpndptsaaqseilraitapdssatedekpqvngtsdvqatparsqln 542
                 444444444455555555566666666666555555555555666666666666666666666666666666666666666666666666666666666 PP

                 ................................................................................................... CS
                 ................................................................................................... RF
        FtsA  71 ................................................................................................... 70 
                                                                                                                    
  EEA20969.1 543 algrvqdldgtprssvagspapefntplngittagnstpvpekasqsaagassqpsqpsqpvaaqplqqpppqpprtptieerddilpiypldqailts 641
                 666666666666666666666666666666666666666666666666666666666666666666666666666666666666666666666666666 PP

                 .......................GGGGSTTHHHHHHH CS
                 .......................xxxxxxxxxxxxxx RF
        FtsA  71 .......................ggsalpnleelaer 84 
                                        ggs+++++  ++e+
  EEA20969.1 642 ithaarsddkkmrdflggimvvgGGSQINGFHAYLEE 678
                 6666666666666666666666666666666655555 PP

>> DUF2114  Uncharacterized protein conserved in archaea (DUF2114)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.1   6.7e-05       0.2     391     448 ..     322     381 ..     314     382 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 6.7e-05
     DUF2114 391 ieelglyddkeenvvfvddgLa..rGaavmarCmnslGtpknPlGGvrggkCilkkrikl 448
                 i e+ + + ++ +v f++++La   Ga   + C+  +G +k+ +  v++g+C+ ++ri+l
  EEA20969.1 322 ILEMLMKEFSFARVCFIQESLAaaFGAGYTTTCIVDIGAQKTSICCVEEGMCVENSRINL 381
                 4466677778999******996336*******************************9986 PP

>> DUF4106  Protein of unknown function (DUF4106)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   7.6    0.0018       5.3     209     248 ..     587     625 ..     553     657 .. 0.72

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0018
     DUF4106 209 vqnpaqqptq..qptvqqpaqvqqpaqqpppqpaqqptvqnp 248
                  q  a   +q  qp+  qp    qp qqpppqp + pt+++ 
  EEA20969.1 587 SQSAAGASSQpsQPS--QPV-AAQPLQQPPPQPPRTPTIEER 625
                 333333222200455..677.789**************9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (745 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       606  (0.0338); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.67u 0.30s 00:00:00.97 Elapsed: 00:00:00.44
# Mc/sec: 5121.36
//
Query:       EEA20970.1  [L=182]
Description: ADP-ribosylation factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.5e-73  244.8   0.1    4.3e-73  244.5   0.1    1.0  1  Arf        ADP-ribosylation factor family
    1.5e-13   51.0   0.0      2e-13   50.6   0.0    1.2  1  Roc        Ras of Complex, Roc, domain of DAPkinase
    2.6e-11   43.3   0.0    3.2e-11   43.0   0.0    1.2  1  SRPRB      Signal recognition particle receptor beta subunit
    3.2e-10   39.9   0.0    3.8e-10   39.6   0.0    1.1  1  Ras        Ras family
    2.9e-09   36.6   0.2    4.3e-05   22.8   0.0    2.4  2  G-alpha    G-protein alpha subunit
      6e-08   32.3   0.0    7.9e-08   31.9   0.0    1.2  1  Gtr1_RagA  Gtr1/RagA G protein conserved region
    5.4e-06   26.5   0.0    9.6e-06   25.7   0.0    1.4  1  MMR_HSR1   50S ribosome-binding GTPase
    0.00058   19.5   0.0      0.046   13.3   0.0    2.1  2  GTP_EFTU   Elongation factor Tu GTP binding domain
     0.0089   15.6   0.6      0.039   13.5   0.6    2.0  1  FeoB_N     Ferrous iron transport protein B


Domain annotation for each model (and alignments):
>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  244.5   0.1   2.1e-76   4.3e-73       7     175 .]      10     177 ..       5     177 .. 0.97

  Alignments for each domain:
  == domain 1  score: 244.5 bits;  conditional E-value: 2.1e-76
                 GGTT.TTEEEEEEEESTTSSHHHHHHHHHHSSCEECSSSSSEEEEEEEETTEEEEEEEE-SSGGGGGGGGGGCTTESEEEEEEETT-CTTHHHHHHHHH CS
         Arf   7 klklkkkelrilllGLDnaGKtTilkklkleelvttvPTigfnveeleiknlkftvwDvGGqeklRplWknYfektdavifvvDsadreRleeakeeLk 105
                 +l  +kke+ril+lGLDnaGKtT+l++lk +e+vtt+PTigfnve++++knl+++vwD+GGq+++Rp+W++Y+++t av+fv+Ds+d eRl  a +eL+
  EEA20970.1  10 SLIWAKKEIRILILGLDNAGKTTLLYRLKIGEVVTTIPTIGFNVESVTYKNLNLNVWDLGGQTSIRPYWRCYYANTAAVVFVIDSTDIERLGIAADELA 108
                 455569********************************************************************************************* PP

                 HHCTSGCCTTSEEEEEEE-TTSTTSS-HHHHHHHTTGGGSSSSSSEEEEEEBTTTTBTHHHHHHHHHHHH CS
         Arf 106 alleeeelkevallvlaNKqDlpealseeelrellgleelkgkrkleiqkcsavkgeglkeglewlsesi 175
                 a+l+eeel+++allv+aNKqD p+a  + e++e+l+l el+ +r+++i++csa+ g+g++eg++wl+++i
  EEA20970.1 109 AMLNEEELRDAALLVFANKQDQPGAKGAGEISEALKLGELR-DRNWSIVACSAIDGKGINEGMDWLVQTI 177
                 *****************************************.*************************986 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.6   0.0     1e-16     2e-13       1     119 [.      19     129 ..      19     130 .. 0.78

  Alignments for each domain:
  == domain 1  score: 50.6 bits;  conditional E-value: 1e-16
                 EEEEESSTTSSHHHHHHCHCT-CCC-EEETTTTEEEEEEECGGSGGCTTBTTTTCEEEEEEEE-SGGCTTTT-HHHHCTSCEEEEEEEGHHHHCH.... CS
         Roc   1 KvvlvGdsgvGKtsllkrfvedkfsekekstigvdfltkevtkikgvendkkvkkvklniWDtaGqerfrslhplylreaalailvydsrssenl.... 95 
                 +++++G  ++GKt+ll r+  +++  ++ +tig ++ + ++            k+++ln+WD++Gq+ +r   ++y+ + a++++v+ds++ e+l    
  EEA20970.1  19 RILILGLDNAGKTTLLYRLKIGEVV-TTIPTIGFNVESVTY------------KNLNLNVWDLGGQTSIRPYWRCYYANTAAVVFVIDSTDIERLgiaa 104
                 699*******************996.568*****9966433............4689*******************************99988762221 PP

                 HHHHHHHHHHCS.SS-EEEEEE-TT CS
         Roc  96 keWlkelkkvag.kspvilvgnkiD 119
                 +e    l+++   ++ +++ +nk D
  EEA20970.1 105 DELAAMLNEEELrDAALLVFANKQD 129
                 3444444443331445667789988 PP

>> SRPRB  Signal recognition particle receptor beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.0   0.0   1.6e-14   3.2e-11       3     138 ..      17     144 ..      15     179 .. 0.87

  Alignments for each domain:
  == domain 1  score: 43.0 bits;  conditional E-value: 1.6e-14
                 --EEEEE-STTSSHHHHHHHHHHSS---B---S.S-EEETTG...GGTT-SEEEETT-GCCSHHHHHHHHHHGGEEEEEEEEETTS-HHHHHHHHHHHH CS
       SRPRB   3 kpavllvGlsdsGKTslftrLttdsvkktvtSq.essaalkvksekgskltliDfPGheklrqklleklkaksslkglvfvvDStidpkevkevAElly 100
                 + ++l++Gl ++GKT+l+ rL  ++v +t   +  +  +  +   k+ +l++ D+ G+ ++r     +    ++  ++vfv+DSt d  ++   A+ l 
  EEA20970.1  17 EIRILILGLDNAGKTTLLYRLKIGEVVTTIPTIgFNVESVTY---KNLNLNVWDLGGQTSIRPYWRCY---YANTAAVVFVIDST-DIERLGIAADELA 108
                 5689**************************999777777777...9****************987665...788899*******9.5566888899999 PP

                 HHHHHHHHHTT---EEEEEE-TTSTT---HHHHHHHHH CS
       SRPRB 101 eilliteklkdavdiliACnKqelflakspklikdaLE 138
                  +l + e l+da  +l+  nKq+   ak +  i +aL 
  EEA20970.1 109 AMLNEEE-LRDA-ALLVFANKQDQPGAKGAGEISEALK 144
                 9999888.4554.688888****************995 PP

>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.6   0.0   1.9e-13   3.8e-10       1     161 [.      19     178 ..      19     179 .. 0.83

  Alignments for each domain:
  == domain 1  score: 39.6 bits;  conditional E-value: 1.9e-13
                 EEEEEESTTSSHHHHHHHHHHSSCSSSCTTTSSEEEEEEEEEETTEEEEEEEEEETTSGGGHHHHHHHHTTESEEEEEEETTBHHHHHTHH.HHHHHHH CS
         Ras   1 KlvlvGdsavGKtslllrfvkdkFkeeyesTigvdfytkeievdgkevkleiwDTAGqeefkslrelyyrdaegillvyditsresfenvk.kwveeik 98 
                 +++++G  + GKt+ll+r   ++  ++ ++Tig++    ++    k+++l++wD  Gq   +   + yy ++ +++ v d t+ e +  ++ ++   ++
  EEA20970.1  19 RILILGLDNAGKTTLLYRLKIGEVVTT-IPTIGFNVE--SV--TYKNLNLNVWDLGGQTSIRPYWRCYYANTAAVVFVIDSTDIERLGIAAdELAAMLN 112
                 5899*******************8875.9***87655..44..45789***************************999999999999887745666666 PP

                 HHSTTTSEEEEEEETTTGGG.G-SS-HHHHHHHH..HHHTSEEEEEBTTTTCTHHHHHHHHHHHHH CS
         Ras  99 rvaeenvpivLvGnKvDlee.kravsteegeela..kelglkfletSAktnenveeafeellreil 161
                 +   ++ ++++ +nK D    k a + +e+ +l   ++ +   + +SA + ++++e ++ l+++i+
  EEA20970.1 113 EEELRDAALLVFANKQDQPGaKGAGEISEALKLGelRDRNWSIVACSAIDGKGINEGMDWLVQTIQ 178
                 665589***********98744444556666665336777999**************999999885 PP

>> G-alpha  G-protein alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.4   0.1   6.4e-05      0.13      21      45 ..      15      39 ..      12      44 .. 0.89
   2 !   22.8   0.0   2.2e-08   4.3e-05     186     276 ..      46     125 ..      40     134 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 6.4e-05
                ..EEEEEEEESTTSSHHHHHHHHHH CS
     G-alpha 21 krevkllllGqseSGKsTilkqlkl 45
                k+e+++l+lG +  GK+T+l  lk+
  EEA20970.1 15 KKEIRILILGLDNAGKTTLLYRLKI 39
                459*****************99986 PP

  == domain 2  score: 22.8 bits;  conditional E-value: 2.2e-08
                 ----SEEEEEEECT-TEEEEEEEE-SSHHHHHGTCCCTTTECEEEEEEEGGGTT-B-SS-TTSBHHHHHHHHHHCCCC-GGGTTSEEEEEE CS
     G-alpha 186 lktvGisetkfevdsklefrivdvgGqrserkkWvpffddvdaiiFlvslsefdqvlyedekvnrleeslklFkeicnnkllkntpiiLfl 276
                 ++t+G++  ++ ++ +l+++++d+gGq s r+ W  ++ ++ a++F++   ++  +            + +   +++n+++l+++ +++f 
  EEA20970.1  46 IPTIGFNVESVTYK-NLNLNVWDLGGQTSIRPYWRCYYANTAAVVFVIDSTDIERL----------GIAADELAAMLNEEELRDAALLVFA 125
                 68999999999998.********************************886666543..........3344444444555555555555555 PP

>> Gtr1_RagA  Gtr1/RagA G protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.9   0.0     4e-11   7.9e-08       1     123 [.      19     130 ..      19     149 .. 0.81

  Alignments for each domain:
  == domain 1  score: 31.9 bits;  conditional E-value: 4e-11
   Gtr1_RagA   1 kvLLmGksgsGKtsmrsiiFdnylardtlrlgatidveksevrflgnltlnlwDcgGqeafveeylssqkeeifrnvgvliyVfDvesreleedletlk 99 
                 ++L++G  ++GKt++       +   ++++   ti  + ++v +++nl+ln+wD+gGq+++   y      + + n +++++V+D++  ++e+      
  EEA20970.1  19 RILILGLDNAGKTTLL----YRLKIGEVVTTIPTIGFNVESV-TYKNLNLNVWDLGGQTSIR-PY----WRCYYANTAAVVFVIDST--DIERLGIAAD 105
                 589**********974....567889999999**********.89*************9865.55....3678999*********99..6666666666 PP

   Gtr1_RagA 100 eilealrq.yspeakvfvlihKmDl 123
                 e+   l +   ++a + v+ +K D+
  EEA20970.1 106 ELAAMLNEeELRDAALLVFANKQDQ 130
                 6665555414588999999999986 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.7   0.0   4.8e-09   9.6e-06       1     113 [.      19     126 ..      19     128 .. 0.64

  Alignments for each domain:
  == domain 1  score: 25.7 bits;  conditional E-value: 4.8e-09
                 EEEEEESTTSSHHHHHHHH.HTSTEEESSSTTSSSSEEEEEEEETTEEEEEEECGGCSSHHHHHHHHHHHHHH.HHCTSEEEEEEETT..TTCSHHHHH CS
    MMR_HSR1   1 evaivGrpNvGKStLinal.tgekaivsdkpgtTrdinegrvklkgkeielvDtpGliegaseekglgkafla.leeadlillvvdas..eeklkplde 95 
                 +++i+G  N+GK+tL+ +l +ge+  v+ +p  T+  n + v++k+ +++++D+ G         +++  ++    ++ ++++v+d++  e  l     
  EEA20970.1  19 RILILGLDNAGKTTLLYRLkIGEV--VTTIP--TIGFNVESVTYKNLNLNVWDLGG-QT------SIRPYWRCyYANTAAVVFVIDSTdiE-RLGIAAD 105
                 689****************44543..44455..666666667777899********.33......233333331224789******66531.3444556 PP

                 HHHHHHHH...TTSEEEEEEE CS
    MMR_HSR1  96 eleellee...akkplilvln 113
                 el+++l+e   ++  l++ +n
  EEA20970.1 106 ELAAMLNEeelRDAALLVFAN 126
                 777777665444444555555 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.0     0.011        21       4      23 ..      18      37 ..      15      45 .. 0.85
   2 !   13.3   0.0   2.3e-05     0.046      91     193 ..      82     178 ..      41     179 .. 0.71

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.011
                EEEEEEESTTSSHHHHHHHH CS
    GTP_EFTU  4 rnigiighvDhGKtTLtdrL 23
                + i i+g  ++GKtTL+ rL
  EEA20970.1 18 IRILILGLDNAGKTTLLYRL 37
                678999999*******9887 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 2.3e-05
                 HHT-SEEEEEEETT..TBSTHHHHHHHHHHHHTTTE...EEEEEESCGSTHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTTEEEEEEBTTTTBTHHHH CS
    GTP_EFTU  91 lrvlDgavlvvdav..eGvepqteevlrlalkegvp...iivfiNKmDrlkaelkeiveevkqklsrkeeklekygekgekevpvvfgSalkgegvktl 184
                 ++ +  +v+v+d++  e       e++ ++++e+++   + vf NK D+++a+    ++e+  kl          ge ++++ ++v +Sa++g+g+++ 
  EEA20970.1  82 YANTAAVVFVIDSTdiERLGIAADELAAMLNEEELRdaaLLVFANKQDQPGAKGAGEISEAL-KL----------GELRDRNWSIVACSAIDGKGINEG 169
                 55566677888887444467777788888888888888899*********887766666555.45..........222335799*************** PP

                 HHHHHHHSH CS
    GTP_EFTU 185 lealvellp 193
                 ++ lv+ ++
  EEA20970.1 170 MDWLVQTIQ 178
                 **9999887 PP

>> FeoB_N  Ferrous iron transport protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.6   1.9e-05     0.039       2      93 ..      19      99 ..      18     172 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 1.9e-05
                EEEEEESTTSSHHHHHHHHHTTSEEEEESTTSSSEEEEEEEEETTEEEEEEE----SSSSSSSHHHHHHHHHHHCTSSSEEEEEEEGGGHHH CS
      FeoB_N  2 tvalvGnpnvGkttlfnaltgakqkvgNwpGvtvekkegklklkgkeveivDlPGiYslsayseeekvardflleeepdvvvnvvdatnler 93
                ++ ++G  n+Gkttl+ +l    + v   p +  + +++++k  + ++++ Dl G  s+ +y +       +    ++ +vv v+d+t +er
  EEA20970.1 19 RILILGLDNAGKTTLLYRLK-IGEVVTTIPTIGFNVESVTYK--NLNLNVWDLGGQTSIRPYWR------CYY--ANTAAVVFVIDSTDIER 99
                78999*************95.567788888777666666555..99**********99998843......333..34556777777777777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (182 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       399  (0.0222544); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.45u 0.28s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 1246.52
//
Query:       EEA20971.1  [L=822]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
     5e-158  526.3   0.0   6.7e-158  525.9   0.0    1.2  1  DUF3419          Protein of unknown function (DUF3419)
    1.8e-11   44.1   0.0    6.5e-10   39.1   0.0    2.2  2  Methyltransf_23  Methyltransferase domain
    4.2e-09   37.0   0.0      3e-08   34.3   0.0    2.4  2  Methyltransf_25  Methyltransferase domain
    6.8e-09   36.4   0.0    4.4e-08   33.8   0.0    2.2  2  Methyltransf_12  Methyltransferase domain
    3.9e-08   32.9   0.0    7.7e-08   32.0   0.0    1.4  1  Ubie_methyltran  ubiE/COQ5 methyltransferase family
    4.5e-08   33.0   0.0    1.2e-07   31.7   0.0    1.6  1  Methyltransf_31  Methyltransferase domain
    1.2e-05   25.8   0.0    6.4e-05   23.5   0.0    2.2  2  Methyltransf_11  Methyltransferase domain
  ------ inclusion threshold ------
      0.086   11.5   0.1       0.13   10.9   0.1    1.1  1  Xan_ur_permease  Permease family
       0.11   11.7   0.0       0.35   10.1   0.0    1.7  2  Mab-21           Mab-21 protein


Domain annotation for each model (and alignments):
>> DUF3419  Protein of unknown function (DUF3419)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  525.9   0.0  3.4e-161  6.7e-158       2     385 .]     401     794 ..     400     794 .. 0.98

  Alignments for each domain:
  == domain 1  score: 525.9 bits;  conditional E-value: 3.4e-161
     DUF3419   2 keeqFkdeliYaftWEDprvdeeaLklepddrvlaItSaGdNaLsYllaspkrihaVDlNpaqnaLleLKlaairalsyedfwklfGegkhenfeelle 100
                 k++qFkde+iYaf WEDprvd+++L+++++d++l+ItSaGdN+L+Yl++spkrihaVD+Np+qn+LleLK+a++ral ++d+wk+fG+gkh +f+ell 
  EEA20971.1 401 KHTQFKDEYIYAFNWEDPRVDHRLLNINSEDVILTITSAGDNILDYLQKSPKRIHAVDMNPNQNHLLELKVASFRALGFDDVWKIFGDGKHTDFRELLL 499
                 89************************************************************************************************* PP

     DUF3419 101 kklsphLsseafqyWekraekvFss.kgkglyetGgsgrairlarllfrllglrkdvkklleaktleeqreiwekkirplllsklvsklvlsneafllk 198
                 +klsphLss+afqyW +++ +vF+s ++kglyetGgs+ ai+l+r+lf+++gl+   ++l+ea+tl+eqreiw + ir++l+s++++++++++e+f +k
  EEA20971.1 500 TKLSPHLSSQAFQYWLEQT-DVFTSkSNKGLYETGGSRVAIKLVRYLFTIFGLHGVNNRLCEAQTLNEQREIWPT-IRRVLISRILNWAIVKTEWFAWK 596
                 *******************.99**999**********************************************65.*********************** PP

     DUF3419 199 alGvpknqlellekes.................gesvaeyvvdtldpvaeksllsedNyFyllaltgkytkeclPeyLkeeafeklkkrakraldelrl 280
                 a+Gvp+ q++++ +++                 g++++eyvvdt+dpva+++l+s+dNyFy+l+l+gk++++c+P+yL+++a+ekl++++  a+d+lr+
  EEA20971.1 597 AAGVPPPQRNMIIDDYlkrngltggikknsdvsGRAIWEYVVDTFDPVAKDTLISNDNYFYYLCLKGKFSRQCHPTYLTAKAHEKLSSPG--AFDGLRI 693
                 ************9995568999********************************************************************..9****** PP

     DUF3419 281 htdeleevlarlkkksltravllDhmDWled..eeleeeiqelnralkpggrvllRsaaeepwyakrfeklgFkvkavaaresgeeekeleaiDrvnmY 377
                 htd l+ev+ar+++++lt+av++D+mDW++   ++++++ q+ln alk+ggrvllRsa+ +pwy+k+fe++gF++++v+ar +g+      +iDrvnmY
  EEA20971.1 694 HTDGLNEVIARITPRTLTIAVVMDSMDWFNPdeDAAAKQAQALNCALKMGGRVLLRSASIDPWYIKDFEANGFTPRRVGARFPGT------CIDRVNMY 786
                 *****************************94579999************************************************......******** PP

     DUF3419 378 asfwiatk 385
                 as w++tk
  EEA20971.1 787 ASAWVITK 794
                 *****997 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.1   0.0   3.3e-13   6.5e-10       2     153 ..      94     274 ..      93     278 .. 0.74
   2 ?    2.6   0.0     0.055   1.1e+02      26      62 ..     433     478 ..     411     541 .. 0.77

  Alignments for each domain:
  == domain 1  score: 39.1 bits;  conditional E-value: 3.3e-13
  Methyltransf_23   2 daqreeels...dklerllpklragg........rvLdiGcGtG.illevlre.....ngf.svtgvDlspeaveiae...........kakka 66 
                      da r++ l+   d l+ l++ l+ +          ++diG GtG ++ e + +     ++f +v++vDlsp + e a+           + ++ 
       EEA20971.1  94 DATRKRLLCgreDMLALLAAQLKYREsqhqvskpVWVDIGGGTGsYNIEAMNAflpvdKFFsHVYLVDLSPSLLEVARqrferlgwknvTVICR 187
                      55566665555444444444333333445677779*********9899999663333334469*********9999978886666555544444 PP

  Methyltransf_23  67 qkdqfdeqeaae.......pqgkfdlIvlrevlehvpdppellrqiatllkpgGylllseplaslkedrllldwlylvpagrhisffsarslke 153
                          f               +g  d+I+++++l  +pd+ ++++++++l+k +++l + ++ +    d + ++++  v + rh+++  +  ++ 
       EEA20971.1 188 DAREF------RlpgtngaANGGADIITMSYSLSMIPDYYSVVDSLNNLMKSDALLGVVDFYVQNIVDVSCRNYTGGVFN-RHVNWLGRAFWRA 274
                      44444......14455556778**************************************98877899999***999998.***9998665555 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.055
  Methyltransf_23  26 vLdiGcGtGillevlrengfsvtgvDlspeaveiae.........k 62 
                      +L i  +  + l++l++ ++ + +vD++p++++++e         +
       EEA20971.1 433 ILTITSAGDNILDYLQKSPKRIHAVDMNPNQNHLLElkvasfralG 478
                      5556666668899******************999876655554440 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.3   0.0   1.5e-11     3e-08       2      94 ..     130     232 ..     130     234 .. 0.85
   2 ?   -1.4   0.0         2     4e+03       9      35 ..     440     465 ..     437     483 .. 0.73

  Alignments for each domain:
  == domain 1  score: 34.3 bits;  conditional E-value: 1.5e-11
                      EEET-TTSHHHHHHHCTS....T.SSEEEEEESSHHHHHHHHHHHHHTTT.TEEEEESBCCGBS......SSTTTEEEEEEESTGGGSSHHHHH CS
  Methyltransf_25   2 LdlGcGtGrltlalakrl....g.kakvtgvDiseemleaareraeeegl.nvefvqgdaedlp......fedgsfDlvvssgalhhlsdedle 83 
                      +d+G GtG + +++ +++    +  ++v+ vD+s+++le ar+r+e+ g+ nv++++ da+++        ++g  D++++s++l++++  d+ 
       EEA20971.1 130 VDIGGGTGSYNIEAMNAFlpvdKfFSHVYLVDLSPSLLEVARQRFERLGWkNVTVICRDAREFRlpgtngAANGGADIITMSYSLSMIP--DYY 221
                      59***********999988664389*********************9999**********99653355555999********9999987..677 PP

                      HHHHHHHHHEE CS
  Methyltransf_25  84 kalkeiarvLk 94 
                       +++ + +++k
       EEA20971.1 222 SVVDSLNNLMK 232
                      78888777776 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 2
                      SHHHHHHHCTSTSSEEEEEESSHHHHH CS
  Methyltransf_25   9 GrltlalakrlgkakvtgvDiseemle 35 
                      G+++l+ +++   +++++vD+++++  
       EEA20971.1 440 GDNILDYLQKS-PKRIHAVDMNPNQNH 465
                      66666666664.599999999998755 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.8   0.0   2.2e-11   4.4e-08       1      98 [.     130     236 ..     130     237 .. 0.88
   2 ?   -0.6   0.0       1.2   2.3e+03      10      44 ..     443     475 ..     438     483 .. 0.72

  Alignments for each domain:
  == domain 1  score: 33.8 bits;  conditional E-value: 2.2e-11
  Methyltransf_12   1 LeiGcGtGsllrallekl.....pdieytgvDispsaiedakeklakrennnnnnvelealdlldldgg.......ssfDlvvasnvlhhlkdi 82 
                      ++iG+GtGs+  +  +++      +++++ vD+sps +e a++++ + + +n++++  +a++ + l  +       +  D++++s  l+ ++d 
       EEA20971.1 130 VDIGGGTGSYNIEAMNAFlpvdkFFSHVYLVDLSPSLLEVARQRFERLGWKNVTVICRDARE-FRL--PgtngaanGGADIITMSYSLSMIPDY 220
                      69*******************999999********************997666666666555.333..235899******************** PP

  Methyltransf_12  83 revldnirklLkpgGr 98 
                       +v+d++ +l+k ++ 
       EEA20971.1 221 YSVVDSLNNLMKSDAL 236
                      ***********99876 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 1.2
  Methyltransf_12  10 llralleklpdieytgvDispsaiedakeklakre 44 
                      +l++l ++  ++++++vD +p++ +  + k a+ +
       EEA20971.1 443 ILDYLQKS--PKRIHAVDMNPNQNHLLELKVASFR 475
                      45555555..99*********99876666666655 PP

>> Ubie_methyltran  ubiE/COQ5 methyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.0   0.0   3.9e-11   7.7e-08      51     155 ..     129     243 ..     111     265 .. 0.82

  Alignments for each domain:
  == domain 1  score: 32.0 bits;  conditional E-value: 3.9e-11
                      EEEES-TT-HHHHHHHHHHHHHH....EEEEEES-HHHHHHHHHHHHHHTSSTEEEEE--TTT..-TTS-....T-EEEEEEES-GGG-S-HHH CS
  Ubie_methyltran  51 vlDvagGtgDlafklsdsvgekg....kvvvlDinenmLkvgekklkeegkinieflqanaee..Lpfed....dsfDvvtvsfGlrnvtDklk 134
                       +D+ gGtg + ++ +++         +v ++D+++++L+v++++ ++ g +n+  ++ +a e  Lp ++    +  D++t+s+ l  ++D+  
       EEA20971.1 129 WVDIGGGTGSYNIEAMNAFLPVDkffsHVYLVDLSPSLLEVARQRFERLGWKNVTVICRDAREfrLPGTNgaanGGADIITMSYSLSMIPDYYS 222
                      68*********99998876544334689******************************9998733565542222568***************** PP

                      HHHHHHHHEEEEEEEEEEEE- CS
  Ubie_methyltran 135 aLkeayrvlkpGGrlvvlefs 155
                      ++ ++   +k    l v++f 
       EEA20971.1 223 VVDSLNNLMKSDALLGVVDFY 243
                      **********99999888885 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.7   0.0   5.8e-11   1.2e-07       7     113 ..     129     243 ..     124     277 .. 0.82

  Alignments for each domain:
  == domain 1  score: 31.7 bits;  conditional E-value: 5.8e-11
  Methyltransf_31   7 vlDlGCGtGeltfelae....elgpkaevvGiDiseeaielArenaqklgldnveFeqgdiee..leklled....ekfDlilsnevlnaladp 90 
                       +D+G GtG + +e+         + ++v+++D s+  +e+Ar++ ++lg +nv++   d+ e  l+ +          D+i+    l  ++d 
       EEA20971.1 129 WVDIGGGTGSYNIEAMNaflpVDKFFSHVYLVDLSPSLLEVARQRFERLGWKNVTVICRDAREfrLPGT--NgaanGGADIITMSYSLSMIPDY 220
                      58**************955542222567*********************************99545533..1455599**************** PP

  Methyltransf_31  91 dkileeiervlkpggilliedpr 113
                       ++  ++ +++k++  l + d+ 
       EEA20971.1 221 YSVVDSLNNLMKSDALLGVVDFY 243
                      ***********999998888777 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   0.0   3.2e-08   6.4e-05       1      93 [.     130     236 ..     130     239 .. 0.84
   2 ?   -1.8   0.0       2.6   5.2e+03      12      34 ..     445     467 ..     438     482 .. 0.66

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 3.2e-08
                      EEET-TTSHHHHHHH.......HTT.SEEEEEES-HHHHHHHHHHCCHHT-.EEEETTEECCC..TS....S-TT-EEEEEEES-CCC-CCHHH CS
  Methyltransf_11   1 LdvGcGtGrlaeala.......krg.arvvgvDlskemlklakekaseegl.kvefvvadaek..lp....fednsfDlvvssevlhhvedpek 79 
                      +d+G GtG++  + +       k + ++v+ vDls+ +l++a+++ ++ g  +v++++ da++  lp     +++  D++++s +l  ++d  +
       EEA20971.1 130 VDIGGGTGSYNIEAMnaflpvdK-FfSHVYLVDLSPSLLEVARQRFERLGWkNVTVICRDAREfrLPgtngAANGGADIITMSYSLSMIPDYYS 222
                      599***99998888856666644.36************************9***********844554444566699***************** PP

                      HHHHHHHHEEEEEE CS
  Methyltransf_11  80 alkeiaRvLkpgGl 93 
                      +++ +  ++k + l
       EEA20971.1 223 VVDSLNNLMKSDAL 236
                      *9999999998876 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 2.6
                      HHHHHTTSEEEEEES-HHHHHHH CS
  Methyltransf_11  12 ealakrgarvvgvDlskemlkla 34 
                       +l+k  +r+ +vD+++++  l 
       EEA20971.1 445 DYLQKSPKRIHAVDMNPNQNHLL 467
                      45555568888888888776544 PP

>> Xan_ur_permease  Permease family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.1   6.6e-05      0.13     336     367 ..      19      51 ..      16      60 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 6.6e-05
                      -HHHHHHHHHHHHHHHHHHHHHHHHHTTS-.SH CS
  Xan_ur_permease 336 PepvlgGvllvvfgmiaasgvsnlqtvdld.sa 367
                      P + +g++l++vfg++a+++v +lq+++ld ++
       EEA20971.1  19 PHIMVGAALVLVFGLVASVAVLSLQKSKLDwNK 51 
                      9999************************99654 PP

>> Mab-21  Mab-21 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   0.00017      0.35      54      97 ..     329     380 ..     295     409 .. 0.71
   2 ?   -2.3   0.0         1   2.1e+03     269     288 ..     511     530 ..     498     532 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00017
                 GG.......EETTEE-HHHHHHHHHHHHHHHH...HCSSSSEE........E CS
      Mab-21  54 yysllkefvtaegylsakkirsrfqslvekavnllekeievka........s 97 
                 + ++l++ +t++ ylsa+k r+ +++ veka   ++ +  ++a         
  EEA20971.1 329 SIEMLNASWTESPYLSAAKHRQEMNDAVEKATPEIKSKAYESAvvnlstnlP 380
                 334566689**********************655553333332344444441 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1
                 B-SSSTT-BTTSTT-HHHHH CS
      Mab-21 269 phyFipklNLlaelskseld 288
                   y++ + + + + s++ l 
  EEA20971.1 511 FQYWLEQTDVFTSKSNKGLY 530
                 579*********99998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (822 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       575  (0.0320709); expected 358.6 (0.02)
Passed bias filter:                      533  (0.0297284); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.81u 0.34s 00:00:01.15 Elapsed: 00:00:00.56
# Mc/sec: 4397.45
//
Query:       EEA20972.1  [L=396]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.078   13.3   0.0       0.18   12.2   0.0    1.6  1  TSC22     TSC-22/dip/bun family
       0.16   11.3   0.0       0.24   10.7   0.0    1.2  1  Corona_M  Coronavirus M matrix/glycoprotein


Domain annotation for each model (and alignments):
>> TSC22  TSC-22/dip/bun family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0     2e-05      0.18      14      52 ..       9      48 ..       4      52 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2e-05
       TSC22 14 EeVevLkekIkeLeernselee.ENslLkalaspeqleql 52
                E+V +Lk++  +L+   ++ e+  NslL+  +s+e l  l
  EEA20972.1  9 ETVTILKSQYENLLRAARQFENlRNSLLRGGVSSEDLDVL 48
                99******************9659***********99765 PP

>> Corona_M  Coronavirus M matrix/glycoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   2.6e-05      0.24     117     174 ..     238     296 ..     224     310 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 2.6e-05
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXX.XXXX CS
    Corona_M 117 lsvlllGqsvvlpleeaplvitvvllsGvLyv.eGhklakveiedLPkeitvatpsrti 174
                  s++l G + +l +++++  it+ l++ +L   +   + +++++++ + i ++t s  +
  EEA20972.1 238 QSITLNGATRNLIIKNTNSNITPALIREHLDHiHNLIVINIKVDHMNRSICICTNSVHN 296
                 6899**************************7515555566**************88654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (396 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       706  (0.0393775); expected 358.6 (0.02)
Passed bias filter:                      492  (0.0274416); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 2645.67
//
Query:       EEA20973.1  [L=597]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    8.5e-06   25.7   0.0    3.1e-05   23.9   0.0    1.9  2  Lipase_3     Lipase (class 3)
  ------ inclusion threshold ------
       0.11   11.7   0.0        0.2   10.9   0.0    1.3  1  Hydrolase_4  Serine aminopeptidase, S33
       0.25   11.3   0.0        0.4   10.6   0.0    1.2  1  UPF0227      Uncharacterised protein family (UPF0227)


Domain annotation for each model (and alignments):
>> Lipase_3  Lipase (class 3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.0   5.1e-09   3.1e-05      57      84 ..     291     318 ..     251     324 .. 0.82
   2 ?   -3.5   0.0       1.4   8.3e+03       6      35 ..     414     439 ..     414     463 .. 0.61

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 5.1e-09
                 HHHHHTT-EEEEEEEETHHHHHHHHHHH CS
    Lipase_3  57 rllekypeysivvtGHSLGgalAlLaal 84 
                 +  e yp+ ++++tGHSLGga++ L++l
  EEA20973.1 291 NATELYPNSNVWLTGHSLGGAMSGLLGL 318
                 47899******************99876 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 1.4
                 ---------------EEE-HHHH-GTT-EE CS
    Lipase_3   6 Gtesakdwltdldfslteakellekeggkv 35 
                 Gt+++k++++++     e+++++++    v
  EEA20973.1 414 GTHRIKSVIKEVLEAYDEVPPCVPE----V 439
                 6777777777777766666666443....3 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   3.4e-05       0.2      53      90 ..     276     313 ..     272     320 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 3.4e-05
  Hydrolase_4  53 psfddyvdDlaafvekvkeehpelplfllGhSmGGlia 90 
                  ++ ++y++ + ++++++ e +p++++ l GhS+GG+++
   EEA20973.1 276 QDENRYYRAAIELYTNATELYPNSNVWLTGHSLGGAMS 313
                  6678899999999**********************997 PP

>> UPF0227  Uncharacterised protein family (UPF0227)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   6.6e-05       0.4      30      87 ..     270     327 ..     259     339 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 6.6e-05
     UPF0227  30 aielsvlklkedpqqalkeleklvaelgddnillvGssLGGyyatrlgerfglrqvll 87 
                  i+ ++   + + + a++   ++ + + + n+ l G sLGG ++  lg  fgl  v +
  EEA20973.1 270 CITEAMQDENRYYRAAIELYTNATELYPNSNVWLTGHSLGGAMSGLLGLTFGLPTVAF 327
                 5555566667788889999999999999999***********************9988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (597 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       727  (0.0405488); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.71u 0.31s 00:00:01.02 Elapsed: 00:00:00.48
# Mc/sec: 3753.55
//
Query:       EEA20974.1  [L=428]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.3e-10   39.1   0.0      1e-06   28.4   0.0    2.3  2  RNA_pol_I_TF  RNA polymerase I specific initiation factor


Domain annotation for each model (and alignments):
>> RNA_pol_I_TF  RNA polymerase I specific initiation factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.4   0.0   5.6e-11     1e-06      28     118 ..     130     243 ..     102     278 .. 0.80
   2 !    8.5   0.0   7.3e-05       1.3     158     189 ..     316     347 ..     297     353 .. 0.87

  Alignments for each domain:
  == domain 1  score: 28.4 bits;  conditional E-value: 5.6e-11
  RNA_pol_I_TF  28 dskseirsyktkhienltqllhlnilrrnwklAykiFslLiRlp....evdirs..iWplGveiLekleeetsse.................kflew 101
                    s+++    + +h+  lt++lh ++l+ ++  A +++ +L+  +     +dir+   W++G eiL ++++  +++                 +++e+
    EEA20974.1 130 GSQTTEATLHIQHLGVLTTILHRCLLEGDFVRAGRVWGMLLHEKfgkdPIDIRHggRWGIGAEILFRQNTAGTNTsnstshiftrpgfeaakAYYER 226
                   44444455577899999***********************986433337****8557********999987766667999***********99**** PP

  RNA_pol_I_TF 102 lssvysskkafnqstsr 118
                   l+  y+s++a ++  s 
    EEA20974.1 227 LIIQYPSRSARSSASSS 243
                   *****988877665554 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 7.3e-05
  RNA_pol_I_TF 158 leelidklselvLePPysedgelyfllalckl 189
                    +e+  +++e++  PPys+ ++l  l +++ l
    EEA20974.1 316 AQEIAARMDEIMVGPPYSDSPALLRLRGMVAL 347
                   689999*****************999999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (428 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       687  (0.0383178); expected 358.6 (0.02)
Passed bias filter:                      414  (0.0230911); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.22s 00:00:00.73 Elapsed: 00:00:00.41
# Mc/sec: 3103.36
//
Query:       EEA20975.1  [L=584]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.2e-49  166.5   0.0    3.7e-48  163.5   0.0    2.6  2  ECM11     Extracellular mutant protein 11


Domain annotation for each model (and alignments):
>> ECM11  Extracellular mutant protein 11
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.2      0.22   3.9e+03      12      44 ..      63      86 ..      54     124 .. 0.43
   2 !  163.5   0.0   2.1e-52   3.7e-48       1     133 []     421     579 ..     421     579 .. 0.95

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.22
       ECM11 12 yseLekep..Fdhdpaappaelppsldtsetleek 44
                +++ +++p  +d+  ++           ++++ ek
  EEA20975.1 63 FNNQQTQPqqYDFPVTT-----------AQQPPEK 86
                22233322223333222...........2222222 PP

  == domain 2  score: 163.5 bits;  conditional E-value: 2.1e-52
       ECM11   1 DyddeelqqmsyseLekepFdhdpaa.........................ppaelppsldtsetleekleelknl..nekeqheffsslsideWeeaG 72 
                 Dy+de+lq+m++seLekepFdh+p +                         pp+++pp+ dts++++ekl++++++  n++++h+++ss++i++We +G
  EEA20975.1 421 DYPDEVLQYMDFSELEKEPFDHSPGSssplkhqrstpkkpkalppppspssPPPPPPPP-DTSTSPSEKLAYIMTAlpNPTARHNYISSMPITDWELLG 518
                 9*******************************************999886544444455.9**************88********************** PP

       ECM11  73 dwlldqfsellkklkeaRrakrktaaefeaeierReeavrkkgeeldrkLeemkegGkevL 133
                 d+l+dq++e+lk++k++R+a+rkt+a feaei+rR++++ ++++eldrk+ emkegG +vL
  EEA20975.1 519 DELIDQMGEMLKMIKDSRQARRKTTALFEAEIRRRHDQTITEAGELDRKFVEMKEGGLGVL 579
                 ***********************************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (584 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       966  (0.0538792); expected 358.6 (0.02)
Passed bias filter:                      405  (0.0225891); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.23s 00:00:00.80 Elapsed: 00:00:00.39
# Mc/sec: 4444.80
//
Query:       EEA20976.1  [L=684]
Description: VPS9 domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      7e-28   96.9   0.0    1.2e-27   96.1   0.0    1.4  1  VPS9      Vacuolar sorting protein 9 (VPS9) domain


Domain annotation for each model (and alignments):
>> VPS9  Vacuolar sorting protein 9 (VPS9) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   96.1   0.0   6.8e-32   1.2e-27       3     103 ..     226     327 ..     224     328 .. 0.96

  Alignments for each domain:
  == domain 1  score: 96.1 bits;  conditional E-value: 6.8e-32
        VPS9   3 qaseeLkklseaksPreKlkcllrtieeiteavskseegeslgaDdlLPiliyviiksspp..nlysnvqfikrFrsktllegeegYylttleaavefi 99 
                  a ++Lkk++ a+ P +Kl++l+++++ i++a+ ++  g+s++aD++LP liy++i+s p+  n++sn+ fi+rFrs ++++ge++Y+lt+leaa++f+
  EEA20976.1 226 AAGDDLKKMNDAHYPLGKLQHLISAHKAIVDAL-TTLLGSSSSADEILPALIYTLITSPPEgiNVISNLLFIQRFRSVSKINGESAYCLTNLEAAISFL 323
                 5889*****************************.**************************97777********************************** PP

        VPS9 100 esle 103
                 es++
  EEA20976.1 324 ESVD 327
                 *986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (684 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       471  (0.0262703); expected 358.6 (0.02)
Passed bias filter:                      318  (0.0177366); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.26s 00:00:00.84 Elapsed: 00:00:00.41
# Mc/sec: 4985.10
//
Query:       EEA20977.1  [L=832]
Description: RING finger protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      1e-12   48.2   5.1    1.6e-12   47.6   5.1    1.3  1  zf-RING_2     Ring finger domain
    1.2e-09   38.3   2.8    2.3e-09   37.4   2.8    1.4  1  zf-rbx1       RING-H2 zinc finger domain
    1.6e-08   34.2   4.6    2.6e-08   33.5   4.6    1.4  1  zf-C3HC4_2    Zinc finger, C3HC4 type (RING finger)
    9.9e-08   31.7   4.8    1.5e-07   31.1   4.8    1.3  1  zf-C3HC4      Zinc finger, C3HC4 type (RING finger)
    8.3e-07   28.6   1.7    1.5e-06   27.8   1.7    1.4  1  zf-RING_11    RING-like zinc finger
    5.1e-06   26.4   3.3    7.6e-06   25.8   3.3    1.3  1  zf-RING_5     zinc-RING finger domain
    7.5e-05   22.5   2.4    0.00013   21.8   2.4    1.3  1  Prok-RING_4   Prokaryotic RING finger family 4
    0.00018   21.1   2.5    0.00028   20.4   2.5    1.2  1  Zn_ribbon_17  Zinc-ribbon, C4HC2 type
    0.00036   20.3   2.9    0.00059   19.6   2.9    1.3  1  zf-C3HC4_3    Zinc finger, C3HC4 type (RING finger)
    0.00039   20.4   2.3    0.00077   19.5   2.3    1.5  1  zf-ANAPC11    Anaphase-promoting complex subunit 11 RING-H2 f
    0.00086   19.3   4.0     0.0018   18.3   4.0    1.5  1  zf-RING_UBOX  RING-type zinc-finger
     0.0054   16.8   5.7     0.0085   16.2   5.7    1.3  1  RINGv         RING-variant domain
  ------ inclusion threshold ------
      0.016   15.0   1.5      0.035   13.9   1.5    1.5  1  zf-Nse        Zinc-finger of the MIZ type in Nse subunit
      0.039   14.0   2.2      0.076   13.1   2.2    1.4  1  zf-C3H2C3     Zinc-finger
      0.093   12.6   1.1       0.18   11.7   1.1    1.5  1  zf-C3HC4_5    Zinc finger, C3HC4 type (RING finger)
       0.26   11.5   3.5       0.48   10.6   3.5    1.4  1  FANCL_C       FANCL C-terminal domain
       0.28   11.1   4.8        0.2   11.6   3.0    1.6  1  Prok-RING_1   Prokaryotic RING finger family 1
       0.47   10.4   4.5       0.76    9.7   4.5    1.3  1  PHD           PHD-finger
       0.71   10.2   2.9        1.3    9.4   2.9    1.3  1  zf-RING-like  RING-like domain
        1.5    8.7   4.1        2.4    8.0   4.1    1.3  1  zf-RING_4     RING/Ubox like zinc-binding domain


Domain annotation for each model (and alignments):
>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.6   5.1   1.7e-15   1.6e-12       2      44 .]     767     811 ..     766     811 .. 0.93

  Alignments for each domain:
  == domain 1  score: 47.6 bits;  conditional E-value: 1.7e-15
   zf-RING_2   2 eCpICleelssadsvlll.pCgHvfhreClerwlrssst.CPlCr 44 
                  C ICl++++ a++v++l +C+H +h+eC+++wl++ ++ CPlCr
  EEA20977.1 767 RCLICLSDYEAAEDVRQLtKCKHLYHKECIDQWLTTGRNsCPLCR 811
                 6***************7779*************9888888****9 PP

>> zf-rbx1  RING-H2 zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.4   2.8   2.6e-12   2.3e-09      13      55 .]     767     811 ..     762     811 .. 0.78

  Alignments for each domain:
  == domain 1  score: 37.4 bits;  conditional E-value: 2.6e-12
     zf-rbx1  13 acieckapgdee.cpvvlGeCgHaFHlhCiskWlkt.rkvCPlcr 55 
                  c+ c ++ ++   +  l +C+H +H++Ci++Wl+t r++CPlcr
  EEA20977.1 767 RCLICLSDYEAAeDVRQLTKCKHLYHKECIDQWLTTgRNSCPLCR 811
                 5666655544443445567*****************9*******8 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.5   4.6   2.9e-11   2.6e-08       1      40 []     767     810 ..     767     810 .. 0.89

  Alignments for each domain:
  == domain 1  score: 33.5 bits;  conditional E-value: 2.9e-11
  zf-C3HC4_2   1 kCpiCldmlkdpsvvt...pCgHvfCqkCilrsLeekn.eCPlC 40 
                 +C iCl  ++ + +v    +C+H ++++Ci+++L+ +  +CPlC
  EEA20977.1 767 RCLICLSDYEAAEDVRqltKCKHLYHKECIDQWLTTGRnSCPLC 810
                 6*****9999887765555****************9988***** PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.1   4.8   1.7e-10   1.5e-07       1      41 []     768     810 ..     768     810 .. 0.96

  Alignments for each domain:
  == domain 1  score: 31.1 bits;  conditional E-value: 1.7e-10
                 -TTT-S--SS-E....E-TTS--B-CHHHHHHHHCTSSB--TTT CS
    zf-C3HC4   1 CpiCleeakepn...elleCkHsfCskCirkilksrkkvkCPlC 41 
                 C iCl+ ++ +    +l++CkH ++++Ci+++l   + ++CPlC
  EEA20977.1 768 CLICLSDYEAAEdvrQLTKCKHLYHKECIDQWLT-TGRNSCPLC 810
                 99******9999999*******************.88899**** PP

>> zf-RING_11  RING-like zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   1.7   1.7e-09   1.5e-06       2      29 .]     768     796 ..     768     796 .. 0.85

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 1.7e-09
  zf-RING_11   2 CsICLeefkpgqalf.ilpCsHtFHfkCI 29 
                 C ICL++++  + ++ +++C+H++H +CI
  EEA20977.1 768 CLICLSDYEAAEDVRqLTKCKHLYHKECI 796
                 9********7776652668*********9 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   3.3   8.5e-09   7.6e-06       1      43 [.     767     811 ..     767     812 .. 0.95

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 8.5e-09
   zf-RING_5   1 hCnkCfekl.skeekfyltsCgHifCekClkkll.ekeavCpiCr 43 
                 +C +C + +   e+   lt+C+H ++++C+++ l + ++ Cp+Cr
  EEA20977.1 767 RCLICLSDYeAAEDVRQLTKCKHLYHKECIDQWLtTGRNSCPLCR 811
                 6********989999*****************999*********8 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   2.4   1.4e-07   0.00013       1      37 [.     768     811 ..     768     818 .. 0.86

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 1.4e-07
  Prok-RING_4   1 CvlCgeq....ekkailepCgHlvCkeCfdskdls...sCPlCq 37 
                  C++C +     e ++ l  C+Hl  keC d++  +   sCPlC+
   EEA20977.1 768 CLICLSDyeaaEDVRQLTKCKHLYHKECIDQWLTTgrnSCPLCR 811
                  999998888889999*****************554455*****9 PP

>> Zn_ribbon_17  Zinc-ribbon, C4HC2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   2.5   3.2e-07   0.00028       5      48 ..     766     812 ..     763     820 .. 0.78

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 3.2e-07
  Zn_ribbon_17   5 ksCayC..elavkgrvvlcgvCeHvlHasCarewfenddlaeCps..G 48 
                   + C +C  + ++   v   ++C+H  H++C+++w++++  ++Cp   G
    EEA20977.1 766 ERCLIClsDYEAAEDVRQLTKCKHLYHKECIDQWLTTGR-NSCPLcrG 812
                   56777744456677788889*******************.9**97334 PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   2.9   6.6e-07   0.00059       3      45 ..     766     812 ..     764     814 .. 0.81

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 6.6e-07
                 SB-TTTSSS....BS-EEETTEEEEEE-HHHHHHHHH.TT-B-TTT-- CS
  zf-C3HC4_3   3 eeCviCler....prnvvllpCgHlvlCeeCaekllk.rkkkCpiCrr 45 
                 e C+iCl+     +    l +C+Hl + +eC +++l   +++Cp+Cr 
  EEA20977.1 766 ERCLICLSDyeaaEDVRQLTKCKHL-YHKECIDQWLTtGRNSCPLCRG 812
                 78******5333244457779****.99********99********96 PP

>> zf-ANAPC11  Anaphase-promoting complex subunit 11 RING-H2 finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   2.3   8.6e-07   0.00077      49      80 ..     784     813 ..     758     818 .. 0.85

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 8.6e-07
                 EBTTS-EEEHHHHHHHHHHHSTSSB-TTTSSB CS
  zf-ANAPC11  49 lGkckhnfhlhcilkwletetskglcpmcrqt 80 
                 l kckh +h+ ci +wl t   ++ cp+cr +
  EEA20977.1 784 LTKCKHLYHKECIDQWLTT--GRNSCPLCRGQ 813
                 679**************75..6899****965 PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   4.0     2e-06    0.0018       1      39 []     768     808 ..     768     810 .. 0.74

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 2e-06
  zf-RING_UBOX   1 CpIClelft...dPlv.l.pCGHtFCreClwelskslegafkCP 39 
                   C ICl++++   d +  l +C H +++eC+   +    g+ +CP
    EEA20977.1 768 CLICLSDYEaaeD-VRqLtKCKHLYHKECI--DQWLTTGRNSCP 808
                   99*******6542.344449**********..455666666666 PP

>> RINGv  RING-variant domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   5.7   9.5e-06    0.0085       1      48 []     768     810 ..     768     810 .. 0.96

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 9.5e-06
                 ETTTTEE-SSSS--B-SS--STCCCSB-HHHHHHHHHHTCT-SB-TTT CS
       RINGv   1 CriCleeeeeseplispCkCrGslklvHesClekWldekeantqCeiC 48 
                 C iCl + e +e++ +  kC+    l H++C+++Wl++    ++C +C
  EEA20977.1 768 CLICLSDYEAAEDVRQLTKCKH---LYHKECIDQWLTT--GRNSCPLC 810
                 99******************96...************9..9999***9 PP

>> zf-Nse  Zinc-finger of the MIZ type in Nse subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   1.5   3.9e-05     0.035      28      56 ..     785     810 ..     765     811 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 3.9e-05
                 SSS--EEEHHHHHHHCTTTS-EE-SCCC- CS
      zf-Nse  28 kkCpHvFEreaIlelikrkktvkCPvagC 56 
                 +kC+H + +e I + + ++ +  CP+  C
  EEA20977.1 785 TKCKHLYHKECIDQWL-TTGRNSCPL--C 810
                 7***************.9999****9..7 PP

>> zf-C3H2C3  Zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   2.2   8.5e-05     0.076      16      34 ..     786     810 ..     785     811 .. 0.75

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 8.5e-05
   zf-C3H2C3  16 sCkHlvHakCade......evCPkC 34 
                 +CkHl+H++C d+      + CP+C
  EEA20977.1 786 KCKHLYHKECIDQwlttgrNSCPLC 810
                 8*********885333333679999 PP

>> zf-C3HC4_5  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   1.1    0.0002      0.18       2      48 ..     766     810 ..     765     813 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.0002
  zf-C3HC4_5   2 eiCPvCkssrYlnpdleflinpeCYhkmCesCvdRlFsdGPnqCPva 48 
                 e C +C s+    +d++ l  ++C h   ++C+d   ++G n+CP  
  EEA20977.1 766 ERCLICLSDYEAAEDVRQL--TKCKHLYHKECIDQWLTTGRNSCPLC 810
                 6788888888888888888..57999999****************75 PP

>> FANCL_C  FANCL C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   3.5   0.00053      0.48       3      46 ..     766     805 ..     764     812 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00053
                 -S-SSS--SS-TT-----B--S-TT----B-SGGGHHHHHHHHS CS
     FANCL_C   3 veCgiCyayrldsgevpdisCdnekCnkkfHsaCLkeWlrslke 46 
                  +C iC++         + + + +kC++ +H++C+ +Wl + ++
  EEA20977.1 766 ERCLICLSDYEAA----EDVRQLTKCKHLYHKECIDQWLTTGRN 805
                 5799998877744....4445567***************98766 PP

>> Prok-RING_1  Prokaryotic RING finger family 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   3.0   0.00022       0.2       5      37 ..     766     798 ..     763     807 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00022
  Prok-RING_1   5 kkCpvCgkelkeedDiVvCpeCgtpyHraCyek 37 
                  ++C +C    + ++D+ + ++C+  yH++C ++
   EEA20977.1 766 ERCLICLSDYEAAEDVRQLTKCKHLYHKECIDQ 798
                  78****************************765 PP

>> PHD  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   4.5   0.00085      0.76       1      50 [.     767     811 ..     767     813 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00085
                 SBTTTTSTTSTTSCEEEETTTSCEEETTTSSSTHSHHSHHSSTBSSTTTH CS
         PHD   1 rCavCkkksdeeeelvqCdgCkrwfHqkClkppleseekpegewlCekCk 50 
                 rC +C ++ ++ e++ q  +Ck+ +H++C++  l++ ++      C+ C+
  EEA20977.1 767 RCLICLSDYEAAEDVRQLTKCKHLYHKECIDQWLTTGRN-----SCPLCR 811
                 6******9999*******************998883333.....477776 PP

>> zf-RING-like  RING-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   2.9    0.0014       1.3      18      43 .]     786     810 ..     782     810 .. 0.90

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0014
  zf-RING-like  18 sCnvrlHvdCfqhyirthsskkCpkC 43 
                   +C+  +H++C+++ + t  +++Cp C
    EEA20977.1 786 KCKHLYHKECIDQWL-TTGRNSCPLC 810
                   8**************.77888****9 PP

>> zf-RING_4  RING/Ubox like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   4.1    0.0027       2.4       1      44 [.     768     811 ..     768     813 .. 0.93

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0027
   zf-RING_4   1 cplCdeeldetdkdlkpCeCgyqiClfCyhrileeeegrCPaCr 44 
                 c +C ++ ++ ++  +  +C++     C ++ l++  + CP Cr
  EEA20977.1 768 CLICLSDYEAAEDVRQLTKCKHLYHKECIDQWLTTGRNSCPLCR 811
                 889999999999999999*************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (832 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       527  (0.0293937); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                        22  (0.00122706); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              20  [number of targets reported over threshold]
# CPU time: 0.65u 0.26s 00:00:00.91 Elapsed: 00:00:00.42
# Mc/sec: 5937.34
//
Query:       EEA20978.1  [L=224]
Description: phosphoribosylglycinamide formyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.1e-35  121.5   0.0    3.6e-35  121.3   0.0    1.0  1  Formyl_trans_N  Formyl transferase


Domain annotation for each model (and alignments):
>> Formyl_trans_N  Formyl transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.3   0.0     2e-39   3.6e-35       2     178 ..       6     207 ..       5     210 .. 0.90

  Alignments for each domain:
  == domain 1  score: 121.3 bits;  conditional E-value: 2e-39
                     EEEEEESESSHHHHHHHHHHHHTTSE....CEEEEEEESCTTEHCHHHHHHCCHCCCECHHCC............SCCCCCCCHHHHHHHHCTT- CS
  Formyl_trans_N   2 kivvlisgtgsnlqalldalkkgsle....advvlvvsnkdkaaglekaeaasiptkvfeekk............leprsqfeeelaeelkelka 80 
                     ++ vlisg+gsnlqa++d+  k+  +     ++v v+sn+++a+gle+a +a+ipt + +  k              +r++++ ela+ + + k+
      EEA20978.1   6 RLTVLISGNGSNLQAVIDEIAKSPDSrlsnTQIVRVLSNRKTAYGLERASKAGIPTTYHNLLKykkahpatpegiQASREEYDAELARLVIADKP 100
                     789****************988776667789*************************9988777778********777789*************** PP

                     SEEEEES--S---HHHH...HSSTTSEEEEESSSTTTTBSS-HHHHH...HHTTS.SEEEEEEEE--SSSSTS-EEEEEEEE--T..T--HHHHH CS
  Formyl_trans_N  81 dlivlagymkllpkelv...qavrlkilniHpSLLPrfkGaaaiqra...leaGd.ketGvtihfvdeelDtGailaqkkveiia..edtkeele 166
                     dl+ + g+m +l+  ++   ++   +i+n+Hp+L+++f+G++ai+ra   +++G  ++tGv+ih v  e+D G+++++k+++ ++  ++++e+ +
      EEA20978.1 101 DLVACLGFMHVLSTRFLvplEEAGIRIVNLHPALPGAFNGVDAIERAhaaWQEGSiTKTGVMIHNVISEVDMGQPILVKEIPFVKgvDEDLEKFK 195
                     ****************876688899******************998622266776356************************998899******* PP

                     HHHHHHHHHHHH CS
  Formyl_trans_N 167 qrvadaehkalv 178
                     ++v+ +e  a++
      EEA20978.1 196 EKVHAVEWGAVI 207
                     ****99976665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (224 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       380  (0.0211947); expected 358.6 (0.02)
Passed bias filter:                      356  (0.0198561); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.30s 00:00:00.76 Elapsed: 00:00:00.46
# Mc/sec: 1462.63
//
Query:       EEA20979.1  [L=723]
Description: C6 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.8e-20   71.2   2.3    1.3e-19   70.3   2.3    1.5  1  Fungal_trans_2  Fungal specific transcription factor domain
    2.2e-07   30.9  12.4    2.2e-07   30.9  12.4    1.6  2  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
          1    7.8   6.9        1.4    7.4   6.9    1.2  1  Macoilin        Macoilin family


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.3   2.3   2.2e-23   1.3e-19      21     373 ..     296     665 ..     275     675 .. 0.85

  Alignments for each domain:
  == domain 1  score: 70.3 bits;  conditional E-value: 2.2e-23
  Fungal_trans_2  21 snpfrkvllplalsnkallhallalsafhlqskgpkdslereakrykslalkelqealaelsstlsrnekykdiLaaiLllcsieissgdvsdwr 115
                        fr +l+ +al+ ++ll+a++ ++a+h +  +p+    ++ ++y+++++++l+++la  +++ +      ++La+iL l  +e   gd  + +
      EEA20979.1 296 DLFFRGTLIDMALEYEPLLYAVVGFAAYHHTLEQPRGK-LNNFLKYYNQSIQLLRKSLASGEKHNE------ATLATILQLSTFEETIGDFMNLG 383
                     55699************************977777776.89*************************......******************999** PP

  Fungal_trans_2 116 vhLeaatsliksrggskasssslsskarfllrifayldilssttlgrgpsfpseeyekllenkkeesdsgldp....lmGcsnslilliseisrL 206
                      h++aa  l++ ++ +  ++ ++++ +rfl  + + +d+++++  +++  ++ e y+++ ++++ +   +ld+    l  + ++l l   e ++L
      EEA20979.1 384 DHHQAADQLMHELLTP--QTITENAIHRFLFVWHSRFDLVACILASNEAILEREWYTSMEQHDTALAARNLDDpimqLNAMTSRLRLFALEYASL 476
                     ****************..9*******************************************555555554444444****************** PP

  Fungal_trans_2 207 arekrsarkdseleplsileeaseleqrllswkprssdlepdldeterassls.........kdltelfrlaaliylyrlvlglpps........ 284
                      ++  s        p++++ +++ l++ ++++++ +++++++ + t +  +           +d+t  f+  +  +++ l +++ ++        
      EEA20979.1 477 FARFASGVIN----PEQFQIRYDYLNEVIDDLHQALKAYDDCEEITMPGPAVPlqgpedildTDMTCRFYRDSKFFMNFLWPDILATvlmfkyqs 567
                     **********....******************************999999999999988887666666888888888877766666666677778 PP

  Fungal_trans_2 285 ...........spevqelvkkllellellpsspv..aiasLlWplFiaGceavdeddRdfvrrrleeleqsrlgnvrrarqvleevWrrrddgee 366
                                 +++   +++  e l+++p+ +v   i +  W ++++     d+ + ++ rr+++++e+s++  +  ar+ l e+W++      
      EEA20979.1 568 hlmtghpdgseLQSIALRICHHAESLARWPEVEVgiTIGGHNWLALTTMFLPRDDKHMQWSRRMFARMEISGYVYAPIARRALAELWNDPS---- 658
                     888888885555555555666666666666666655999999*****999999999999****************************9877.... PP

  Fungal_trans_2 367 kidWrdv 373
                        W+d 
      EEA20979.1 659 VEEWWDP 665
                     5567775 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.9  12.4   3.7e-11   2.2e-07       2      39 ..     102     138 ..     101     139 .. 0.92
   2 ?   -3.3   0.1       1.7     1e+04      29      36 ..     538     545 ..     537     546 .. 0.80

  Alignments for each domain:
  == domain 1  score: 30.9 bits;  conditional E-value: 3.7e-11
                 S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus   2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfysesskr 39 
                 +C +Cr+++vKCd+++P+C +Ckk n  C+ y +s  +
  EEA20979.1 102 GCLTCRSRRVKCDEGRPVCDRCKKGNRSCE-YAQSNAK 138
                 6*****************************.9988765 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 1.7
                 HHCCCCTC CS
     Zn_clus  29 eCtfyses 36 
                 +C+fy++s
  EEA20979.1 538 TCRFYRDS 545
                 69999987 PP

>> Macoilin  Macoilin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   6.9   0.00023       1.4     203     375 ..      78     252 ..      65     393 .. 0.62

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.00023
    Macoilin 203 Pkeqqlldkeereae..eqlaaakelvevdpvalsknnhslnkkdsslklpeleyrekkksakssrsdskkkhehn.esvdsklqekeymenkskskrl 298
                 P+ q+ l++++  ae  +++ +  + ++  +  ++ ++  +     ++     ey +++ +++ssr +++++ +h+  s d+++ e+    + +  +  
  EEA20979.1  78 PQSQPQLQQQQLTAEqrKHKRTRSGCLTCRSRRVKCDEGRPVCDRCKKGNRSCEYAQSNAKSTSSRRSTRRQSSHEsISSDEDHAEQGGSLDVIPDEDE 176
                 444433333332222002333444444455555554444444433444444555655555555555555555444435566666666555554443333 PP

    Macoilin 299 sksessgsesellveesvkskssssssssnknskkasagsagssnssskkhsessksvtsssssknskkqklpaGks 375
                  +   ++s  ++ +  ++ s       s ++n  +  ++s +ss s sk++s +s+ v+ss+ss++s   +   G+ 
  EEA20979.1 177 -TAGLPSSLPSVRMAFDSGSARRMRAHSPSNNRPRPRNSSETSSASKSKSLSPASDWVSSSQSSTSSATYQQQRGRF 252
                 .3334444444444333333333333333344445555566677777777888887777777666665555555553 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (723 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1140  (0.0635841); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.72u 0.27s 00:00:00.99 Elapsed: 00:00:00.44
# Mc/sec: 4907.38
//
Query:       EEA20980.1  [L=1200]
Description: DEAD/DEAH box helicase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.5e-27   94.7   0.0    9.6e-27   93.9   0.0    1.3  1  DEAD        DEAD/DEAH box helicase
    5.7e-17   62.3   0.1    2.9e-12   47.1   0.1    2.8  2  DUF1998     Domain of unknown function (DUF1998)
    2.3e-12   47.2   0.1      1e-11   45.2   0.0    2.0  2  Helicase_C  Helicase conserved C-terminal domain
    2.1e-06   27.8   0.0    3.7e-06   27.0   0.0    1.4  1  ResIII      Type III restriction enzyme, res subunit
    5.8e-06   26.7   0.0    1.2e-05   25.6   0.0    1.5  1  CDT1        DNA replication factor CDT1 like
  ------ inclusion threshold ------
          9    6.7   9.9         40    4.6   0.6    3.3  3  NUDE_C      NUDE protein, C-terminal conserved region


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.9   0.0   3.2e-30   9.6e-27       3     170 ..     380     551 ..     378     556 .. 0.88

  Alignments for each domain:
  == domain 1  score: 93.9 bits;  conditional E-value: 3.2e-30
                 HHHHHHHHHHTTCEEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTST.SEEEEE...ETTSSHHHHHHHHHTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxx...xxxxxxxxxxxxxxxx RF
        DEAD   3 iQaeaiplilgggdvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyid.lrvlli...iggvaardqlskldng 97 
                  Qaeai+++++g++v+v+  T sGK+l+++ip+l+++   +++++ + +++ Pt++La+++ + +k+++++++ l+ ++i   + g++   ++++++ +
  EEA20980.1 380 HQAEAINNLYEGHHVIVSTSTSSGKSLIYQIPMLHEL---EKDPNSRGIYIFPTKALAQDQRRSMKELLNFMEgLE-HVIvetFDGDTPMAERNTIRDE 474
                 6*********************************999...689999************************977433.333122669**********999 PP

                 CSEEEEEHHHHHHHH..HCTSSH..CTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTST.TTSEEEEEESSBS CS
                 xxxxxxxxxxxxxxx..xxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxx RF
        DEAD  98 vdivvgtpgrlddll..stgkln..lsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgk.lqrqvivlSATlp 170
                  +i++++p++l+  +  ++g+ +  l++++f+V+DE + +    f+ ++  ++++l++i++       ++i +SAT+ 
  EEA20980.1 475 GRIIFTNPDMLHVTIlpQEGSWRtfLQNLKFVVVDELHAYNGL-FGSHVAFVMRRLRRICAAVGnRYVRFISCSATVA 551
                 ************9666955555556*****************9.**************99998867778*******97 PP

>> DUF1998  Domain of unknown function (DUF1998)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.0   8.9e-05      0.26       1      31 [.     982    1012 ..     982    1030 .. 0.85
   2 !   47.1   0.1   9.9e-16   2.9e-12      17      83 .]    1055    1121 ..    1045    1121 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 8.9e-05
     DUF1998    1 lehalinalplflqcdesdlgteckapedep 31  
                  +eha+++++p+f+ + ++d++teck++++e 
  EEA20980.1  982 AEHAVLSLFPTFIISLPGDVRTECKVAKKEL 1012
                  69***********************887765 PP

  == domain 2  score: 47.1 bits;  conditional E-value: 9.9e-16
     DUF1998   17 esdlgteckapedeprkrpariliydavp..gGaGiaekaaelleellraalelieecdCee.aGCpaCl 83  
                   + l++e+++p+   r+rpar+++yda++  +G+Gia ka+e++++ll +a+++ie+c+C + +GC +C+
  EEA20980.1 1055 NKNLSEELEPPH---RQRPARLTFYDAKGgpSGSGIALKAFEFIDSLLARAVRRIEACTCISpQGCIECV 1121
                  567788887663...68***********9778****************************5579*****8 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       1.4   4.2e+03      31      57 ..     437     470 ..     387     475 .. 0.56
   2 !   45.2   0.0   3.4e-15     1e-11       6     110 ..     609     719 ..     602     720 .. 0.82

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 1.4
                 H....HHHHHHHT.....TSTEEEESTTSTHHHHHH CS
  Helicase_C  31 k....vklllekk.....gikvavlhgelpqneree 57 
                 +     +ll  ++     ++ v +++g++p  er+ 
  EEA20980.1 437 QrrsmKELL--NFmegleHVIVETFDGDTPMAERNT 470
                 122322223..1122333566666777777666665 PP

  == domain 2  score: 45.2 bits;  conditional E-value: 3.4e-15
                 HHHHHHHTTTTSEEEEEESSHHHHHH.....HHHHHHHT........TSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEES CS
  Helicase_C   6 llellkleeeggkilifvntidrlek.....vklllekk........gikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinf 91 
                 +++l     +g ++++f++ ++++e           +++        +  v  + g  + + r++i +++ +g+   ++at+++e G+di +++ Vi +
  EEA20980.1 609 FCQL---VLRGVRVILFCRIRKQCEIalaavR----TEFqtlgrpevANLVMGYRGGYSPQARRQIEKEMFDGKLMGIVATNALELGVDIGSLDAVITL 700
                 3444...58999**********9987744431....2233445555555566778899*********9999**************************** PP

                 SSSSSHHHHHHHHTTSSST CS
  Helicase_C  92 dlprnvtsyiqriGRtgRa 110
                 ++p++++++ q++GR+gR 
  EEA20980.1 701 GFPFSISNLRQQSGRAGRR 719
                 ******************6 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.0   0.0   1.3e-09   3.7e-06       3     146 ..     376     516 ..     374     551 .. 0.80

  Alignments for each domain:
  == domain 1  score: 27.0 bits;  conditional E-value: 1.3e-09
                 EE-HHHHHHHHHHT......TTSEEEEEESTTSTHHHHHHHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG.......GEEEESSS-B--.. CS
      ResIII   3 elreyQeeaienlleklkskrdkrglikmaTGtGKTlvaaklierllkkgkeekflflvprkslleqtleefkkflseayke...igkkvsgdkkka.k 97 
                 +l+ +Q+eai+nl       + +++++   T +GK+l++   + + l+k ++++ + + p+k+l +  ++ +k++l+        i + ++gd+ +a +
  EEA20980.1 376 QLYLHQAEAINNLY------EGHHVIVSTSTSSGKSLIYQIPMLHELEKDPNSRGIYIFPTKALAQDQRRSMKELLNFMEGLehvIVETFDGDTPMAeR 468
                 67889********6......6789***************77777777778999*************999666555554422244599999999999977 PP

                 ......-SEEEEEHHHHHHTH........HHHTTT-SEEEEETGGGTTS CS
      ResIII  98 ekdstnkkilvttiqsldadseeeeeeseellrdrfdviiiDEaHrlga 146
                 +  +++ +i++t+ ++l+  +   +e s +   ++ +++++DE H +++
  EEA20980.1 469 NTIRDEGRIIFTNPDMLHVTI-LPQEGSWRTFLQNLKFVVVDELHAYNG 516
                 888999***************.6677777777777789*******9987 PP

>> CDT1  DNA replication factor CDT1 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.0   4.1e-09   1.2e-05       2      67 ..      76     143 ..      75     174 .. 0.89

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 4.1e-09
        CDT1   2 PskYevLlelFkaldtivsmlenrket.itfakvkkaVermsr.ksfeekhLaqiktvyPeayklkqe 67 
                 P  +++L ++ +al+ +  + ++rk+  +tf+ +k+aV++ +  ++ + +++a+ik ++P a+ +++ 
  EEA20980.1  76 PDAFKRLSQTHRALNLVYTFCCTRKHLaTTFETIKTAVQAQMGgRELTVEDVARIKVLIPRAVRFEYV 143
                 8899*******************9996268999******98877*********************964 PP

>> NUDE_C  NUDE protein, C-terminal conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.6     0.014        40      75     113 ..       9      48 ..       2      87 .. 0.81
   2 ?    3.7   0.0     0.027        80     110     150 ..     283     323 ..     215     336 .. 0.71
   3 ?    2.3   1.2     0.071   2.1e+02      46     102 ..    1000    1053 ..     999    1073 .. 0.62

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.014
      NUDE_C  75 spstp.qsleiekrspavqasssPviatppekslsslatg 113
                 +p++p   ++ +  +pa  a+  P i+tpp+k+ ss ++g
  EEA20980.1   9 QPTAPpVVVNDDLIDPALRATTAPSIETPPKKASSSSTRG 48 
                 45566577788889******************97777766 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.027
      NUDE_C 110 latgsetatppsPpasessdllrkvlaltsklarqrasisd 150
                 + + ++ +  psPp++e sd+l   ++    +++ r+ i++
  EEA20980.1 283 VERLESEKVIPSPPVKEESDNLGAKGKVPDAIPKDRKPIAE 323
                 44444456779**********************99998877 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.071
      NUDE_C   46 DLkveleiiqeklrkaeeklrrrkplslsspstpqsleiekrspavqasssPviatp 102 
                  D + e ++ +++l k  + +r+++ +s  ++st + ++ + +s++  a+ s+     
  EEA20980.1 1000 DVRTECKVAKKELGK--NLKRANEAISS-ASSTNEHTTQHPTSSGRPATVSKSSFAN 1053
                  889999999999988..44455555555.5566655556666666666644433233 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1200 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       679  (0.0378716); expected 358.6 (0.02)
Passed bias filter:                      531  (0.0296168); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.87u 0.32s 00:00:01.19 Elapsed: 00:00:00.50
# Mc/sec: 7289.53
//
Query:       EEA20981.1  [L=292]
Description: C2H2 transcription factor (Con7), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0084   15.9   1.4      0.018   14.8   1.4    1.5  1  HDV_ag    Hepatitis delta virus delta antigen
  ------ inclusion threshold ------
       0.12   13.0   0.9       0.25   12.0   0.7    1.6  1  FOXP-CC   FOXP coiled-coil domain
       0.13   12.8   0.2        0.3   11.6   0.2    1.6  1  zf-C2H2   Zinc finger, C2H2 type
          7    7.3   8.0        2.8    8.6   0.2    2.2  2  YabA      Initiation control protein YabA


Domain annotation for each model (and alignments):
>> HDV_ag  Hepatitis delta virus delta antigen
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   1.4     4e-06     0.018     123     173 ..     186     233 ..     158     243 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 4e-06
      HDV_ag 123 skeeeeelrrlteederrerriagpqvggvnpleggtrgapgggfvpsmqg 173
                  k+eee+ r+ +ee er+    a  q     p+egg+   p gg  ps  g
  EEA20981.1 186 RKKEEENQRKAAEERERQAAAQAQAQG---GPVEGGAPTDPQGGQPPSYAG 233
                 466778889999887777666655554...499**************9876 PP

>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.7   5.5e-05      0.25       6      40 ..     142     176 ..     139     208 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 5.5e-05
     FOXP-CC   6 vCkWPgCekvledveeflkhlnseHalddkstaql 40 
                  C W gCek+  +++++ +h+  + + ++++ +++
  EEA20981.1 142 KCGWNGCEKAYGTLNHLNAHVTMQSHGNKRTPEEF 176
                 6********************98888887776655 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.2   6.7e-05       0.3       1      22 [.     141     164 ..     141     167 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 6.7e-05
                 EEET..TTTEEESSHHHHHHHHHC CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirt 22 
                 ykC+  +C k + +  +L++H  +
  EEA20981.1 141 YKCGwnGCEKAYGTLNHLNAHVTM 164
                 9********************865 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.2   0.00062       2.8      61      91 ..     125     155 ..     122     159 .. 0.88
   2 ?    1.8   3.3     0.084   3.8e+02      24      69 ..     155     200 ..     154     212 .. 0.68

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00062
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        YabA  61 ekkkelsegkenLarlYeeGFHiCnvlyGsr 91 
                 +++k+ ++ +e+++r+Y+ G+  C+  yG+ 
  EEA20981.1 125 QQHKRPRRRYEEIERMYKCGWNGCEKAYGTL 155
                 677888999********************86 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.084
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHXXXXXXXXXXXXXXXXX CS
        YabA  24 leelkeelaelleenaeLeleneklrerleeeekkekekkkelseg 69 
                 l++l+++++   + n++   e +++r++ + ++k+e++++k+ +e 
  EEA20981.1 155 LNHLNAHVTMQSHGNKRTPEEFKEIRKEWKARKKEEENQRKAAEER 200
                 5677788888888888888899999999865555555554444433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (292 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1708  (0.0952647); expected 358.6 (0.02)
Passed bias filter:                      858  (0.0478554); expected 358.6 (0.02)
Passed Vit filter:                       114  (0.00635841); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 1900.40
//
Query:       EEA20982.1  [L=300]
Description: C2H2 transcription factor (Con7), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      0.009   15.8   1.4      0.019   14.8   1.4    1.5  1  HDV_ag    Hepatitis delta virus delta antigen
  ------ inclusion threshold ------
       0.14   12.7   0.2       0.31   11.6   0.2    1.6  1  zf-C2H2   Zinc finger, C2H2 type
       0.14   12.8   1.0       0.28   11.9   0.8    1.6  1  FOXP-CC   FOXP coiled-coil domain
        7.7    7.2   8.0        2.9    8.6   0.2    2.2  2  YabA      Initiation control protein YabA


Domain annotation for each model (and alignments):
>> HDV_ag  Hepatitis delta virus delta antigen
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   1.4   4.2e-06     0.019     123     173 ..     186     233 ..     158     243 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 4.2e-06
      HDV_ag 123 skeeeeelrrlteederrerriagpqvggvnpleggtrgapgggfvpsmqg 173
                  k+eee+ r+ +ee er+    a  q     p+egg+   p gg  ps  g
  EEA20982.1 186 RKKEEENQRKAAEERERQAAAQAQAQG---GPVEGGAPTDPQGGQPPSYAG 233
                 466778889999887777666655554...499**************9876 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.2   6.9e-05      0.31       1      22 [.     141     164 ..     141     167 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 6.9e-05
                 EEET..TTTEEESSHHHHHHHHHC CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirt 22 
                 ykC+  +C k + +  +L++H  +
  EEA20982.1 141 YKCGwnGCEKAYGTLNHLNAHVTM 164
                 9********************865 PP

>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.8   6.1e-05      0.28       6      40 ..     142     176 ..     139     208 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 6.1e-05
     FOXP-CC   6 vCkWPgCekvledveeflkhlnseHalddkstaql 40 
                  C W gCek+  +++++ +h+  + + ++++ +++
  EEA20982.1 142 KCGWNGCEKAYGTLNHLNAHVTMQSHGNKRTPEEF 176
                 6********************98888887776655 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.2   0.00065       2.9      61      91 ..     125     155 ..     122     159 .. 0.88
   2 ?    1.7   3.3     0.089     4e+02      24      69 ..     155     200 ..     154     212 .. 0.68

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00065
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        YabA  61 ekkkelsegkenLarlYeeGFHiCnvlyGsr 91 
                 +++k+ ++ +e+++r+Y+ G+  C+  yG+ 
  EEA20982.1 125 QQHKRPRRRYEEIERMYKCGWNGCEKAYGTL 155
                 677888999********************86 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.089
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHXXXXXXXXXXXXXXXXX CS
        YabA  24 leelkeelaelleenaeLeleneklrerleeeekkekekkkelseg 69 
                 l++l+++++   + n++   e +++r++ + ++k+e++++k+ +e 
  EEA20982.1 155 LNHLNAHVTMQSHGNKRTPEEFKEIRKEWKARKKEEENQRKAAEER 200
                 5677788888888888888899999999865555555554444433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (300 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1752  (0.0977188); expected 358.6 (0.02)
Passed bias filter:                      892  (0.0497518); expected 358.6 (0.02)
Passed Vit filter:                       119  (0.00663729); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.62u 0.32s 00:00:00.94 Elapsed: 00:00:00.48
# Mc/sec: 1884.99
//
Query:       EEA20983.1  [L=247]
Description: C2H2 transcription factor (Con7), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0077   16.1   1.5      0.013   15.3   1.5    1.4  1  HDV_ag    Hepatitis delta virus delta antigen
  ------ inclusion threshold ------
        0.1   13.2   0.9       0.19   12.3   0.7    1.6  1  FOXP-CC   FOXP coiled-coil domain
       0.14   12.7   0.2       0.24   11.9   0.2    1.4  1  zf-C2H2   Zinc finger, C2H2 type
        5.4    7.7   8.2        2.4    8.9   0.2    2.1  2  YabA      Initiation control protein YabA


Domain annotation for each model (and alignments):
>> HDV_ag  Hepatitis delta virus delta antigen
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   1.5     3e-06     0.013     123     173 ..     141     188 ..     113     198 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 3e-06
      HDV_ag 123 skeeeeelrrlteederrerriagpqvggvnpleggtrgapgggfvpsmqg 173
                  k+eee+ r+ +ee er+    a  q     p+egg+   p gg  ps  g
  EEA20983.1 141 RKKEEENQRKAAEERERQAAAQAQAQG---GPVEGGAPTDPQGGQPPSYAG 188
                 466778889999887777666655554...499**************9876 PP

>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.7   4.3e-05      0.19       6      40 ..      97     131 ..      94     163 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 4.3e-05
     FOXP-CC   6 vCkWPgCekvledveeflkhlnseHalddkstaql 40 
                  C W gCek+  +++++ +h+  + + ++++ +++
  EEA20983.1  97 KCGWNGCEKAYGTLNHLNAHVTMQSHGNKRTPEEF 131
                 6********************98888887776655 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.2   5.3e-05      0.24       1      22 [.      96     119 ..      96     122 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 5.3e-05
                 EEET..TTTEEESSHHHHHHHHHC CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirt 22 
                 ykC+  +C k + +  +L++H  +
  EEA20983.1  96 YKCGwnGCEKAYGTLNHLNAHVTM 119
                 9********************865 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.2   0.00053       2.4      61      91 ..      80     110 ..      77     113 .. 0.89
   2 ?    2.0   3.6      0.07   3.1e+02      24      69 ..     110     155 ..     108     167 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00053
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        YabA  61 ekkkelsegkenLarlYeeGFHiCnvlyGsr 91 
                 +++k+ ++ +e+++r+Y+ G+  C+  yG+ 
  EEA20983.1  80 QQHKRPRRRYEEIERMYKCGWNGCEKAYGTL 110
                 677888999********************85 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.07
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHXXXXXXXXXXXXXXXXX CS
        YabA  24 leelkeelaelleenaeLeleneklrerleeeekkekekkkelseg 69 
                 l++l+++++   + n++   e +++r++ + ++k+e++++k+ +e 
  EEA20983.1 110 LNHLNAHVTMQSHGNKRTPEEFKEIRKEWKARKKEEENQRKAAEER 155
                 6678888888888899999999999999965555555555444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (247 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1906  (0.106308); expected 358.6 (0.02)
Passed bias filter:                      996  (0.0555525); expected 358.6 (0.02)
Passed Vit filter:                       139  (0.0077528); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.44
# Mc/sec: 1697.61
//
Query:       EEA20984.1  [L=263]
Description: C2H2 transcription factor (Con7), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0081   16.0   1.4      0.015   15.1   1.4    1.4  1  HDV_ag    Hepatitis delta virus delta antigen
  ------ inclusion threshold ------
       0.15   12.7   1.2       0.28   11.9   1.1    1.6  1  FOXP-CC   FOXP coiled-coil domain
       0.15   12.6   0.2       0.26   11.8   0.2    1.4  1  zf-C2H2   Zinc finger, C2H2 type
        6.4    7.5   8.2        2.6    8.7   0.2    2.1  2  YabA      Initiation control protein YabA


Domain annotation for each model (and alignments):
>> HDV_ag  Hepatitis delta virus delta antigen
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   1.4   3.4e-06     0.015     123     173 ..     157     204 ..     129     214 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 3.4e-06
      HDV_ag 123 skeeeeelrrlteederrerriagpqvggvnpleggtrgapgggfvpsmqg 173
                  k+eee+ r+ +ee er+    a  q     p+egg+   p gg  ps  g
  EEA20984.1 157 RKKEEENQRKAAEERERQAAAQAQAQG---GPVEGGAPTDPQGGQPPSYAG 204
                 466778889999887777666655554...499**************9876 PP

>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   1.1   6.2e-05      0.28       6      41 ..     113     148 ..     110     180 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 6.2e-05
     FOXP-CC   6 vCkWPgCekvledveeflkhlnseHalddkstaqlr 41 
                  C W gCek+  +++++ +h+  + + ++++ ++++
  EEA20984.1 113 KCGWNGCEKAYGTLNHLNAHVTMQSHGNKRTPEEFK 148
                 6********************988888877766554 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.2   5.8e-05      0.26       1      22 [.     112     135 ..     112     138 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 5.8e-05
                 EEET..TTTEEESSHHHHHHHHHC CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirt 22 
                 ykC+  +C k + +  +L++H  +
  EEA20984.1 112 YKCGwnGCEKAYGTLNHLNAHVTM 135
                 9********************865 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.2   0.00058       2.6      61      91 ..      96     126 ..      93     129 .. 0.89
   2 ?    1.9   3.6     0.077   3.4e+02      24      69 ..     126     171 ..     124     183 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00058
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        YabA  61 ekkkelsegkenLarlYeeGFHiCnvlyGsr 91 
                 +++k+ ++ +e+++r+Y+ G+  C+  yG+ 
  EEA20984.1  96 QQHKRPRRRYEEIERMYKCGWNGCEKAYGTL 126
                 677888999********************85 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.077
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHXXXXXXXXXXXXXXXXX CS
        YabA  24 leelkeelaelleenaeLeleneklrerleeeekkekekkkelseg 69 
                 l++l+++++   + n++   e +++r++ + ++k+e++++k+ +e 
  EEA20984.1 126 LNHLNAHVTMQSHGNKRTPEEFKEIRKEWKARKKEEENQRKAAEER 171
                 6678888888888899999999999999965555555555444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (263 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1998  (0.11144); expected 358.6 (0.02)
Passed bias filter:                     1079  (0.0601818); expected 358.6 (0.02)
Passed Vit filter:                       144  (0.00803168); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.64u 0.32s 00:00:00.96 Elapsed: 00:00:00.48
# Mc/sec: 1651.37
//
Query:       EEA20985.1  [L=247]
Description: C2H2 transcription factor (Con7), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0077   16.1   1.5      0.013   15.3   1.5    1.4  1  HDV_ag    Hepatitis delta virus delta antigen
  ------ inclusion threshold ------
        0.1   13.2   0.9       0.19   12.3   0.7    1.6  1  FOXP-CC   FOXP coiled-coil domain
       0.14   12.7   0.2       0.24   11.9   0.2    1.4  1  zf-C2H2   Zinc finger, C2H2 type
        5.4    7.7   8.2        2.4    8.9   0.2    2.1  2  YabA      Initiation control protein YabA


Domain annotation for each model (and alignments):
>> HDV_ag  Hepatitis delta virus delta antigen
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   1.5     3e-06     0.013     123     173 ..     141     188 ..     113     198 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 3e-06
      HDV_ag 123 skeeeeelrrlteederrerriagpqvggvnpleggtrgapgggfvpsmqg 173
                  k+eee+ r+ +ee er+    a  q     p+egg+   p gg  ps  g
  EEA20985.1 141 RKKEEENQRKAAEERERQAAAQAQAQG---GPVEGGAPTDPQGGQPPSYAG 188
                 466778889999887777666655554...499**************9876 PP

>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.7   4.3e-05      0.19       6      40 ..      97     131 ..      94     163 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 4.3e-05
     FOXP-CC   6 vCkWPgCekvledveeflkhlnseHalddkstaql 40 
                  C W gCek+  +++++ +h+  + + ++++ +++
  EEA20985.1  97 KCGWNGCEKAYGTLNHLNAHVTMQSHGNKRTPEEF 131
                 6********************98888887776655 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.2   5.3e-05      0.24       1      22 [.      96     119 ..      96     122 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 5.3e-05
                 EEET..TTTEEESSHHHHHHHHHC CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirt 22 
                 ykC+  +C k + +  +L++H  +
  EEA20985.1  96 YKCGwnGCEKAYGTLNHLNAHVTM 119
                 9********************865 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.2   0.00053       2.4      61      91 ..      80     110 ..      77     113 .. 0.89
   2 ?    2.0   3.6      0.07   3.1e+02      24      69 ..     110     155 ..     108     167 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00053
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        YabA  61 ekkkelsegkenLarlYeeGFHiCnvlyGsr 91 
                 +++k+ ++ +e+++r+Y+ G+  C+  yG+ 
  EEA20985.1  80 QQHKRPRRRYEEIERMYKCGWNGCEKAYGTL 110
                 677888999********************85 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.07
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHXXXXXXXXXXXXXXXXX CS
        YabA  24 leelkeelaelleenaeLeleneklrerleeeekkekekkkelseg 69 
                 l++l+++++   + n++   e +++r++ + ++k+e++++k+ +e 
  EEA20985.1 110 LNHLNAHVTMQSHGNKRTPEEFKEIRKEWKARKKEEENQRKAAEER 155
                 6678888888888899999999999999965555555555444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (247 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1906  (0.106308); expected 358.6 (0.02)
Passed bias filter:                      996  (0.0555525); expected 358.6 (0.02)
Passed Vit filter:                       139  (0.0077528); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.58u 0.32s 00:00:00.89 Elapsed: 00:00:00.47
# Mc/sec: 1578.93
//
Query:       EEA20986.1  [L=554]
Description: RNA helicase (Dbp), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.1e-49  167.7   0.0    6.7e-48  162.8   0.0    2.1  2  DEAD            DEAD/DEAH box helicase
    9.6e-32  109.6   0.0    3.1e-31  108.0   0.0    1.9  2  Helicase_C      Helicase conserved C-terminal domain
    0.00053   20.0   0.0     0.0017   18.4   0.0    1.8  2  ResIII          Type III restriction enzyme, res subunit
     0.0057   15.5   0.0       0.33    9.7   0.0    2.3  2  UTP25           Utp25, U3 small nucleolar RNA-associated SSU 
     0.0059   17.0   0.0        1.7    9.0   0.0    2.4  2  AAA_19          AAA domain
     0.0061   15.8   0.1     0.0089   15.3   0.1    1.2  1  ERCC3_RAD25_C   ERCC3/RAD25/XPB C-terminal helicase
  ------ inclusion threshold ------
      0.073   12.9   0.1       0.14   12.0   0.1    1.4  1  DUF5335         Family of unknown function (DUF5335)
      0.091   12.8   0.4       0.19   11.8   0.4    1.5  1  DUF2443         Protein of unknown function (DUF2443)
       0.15   11.9   0.0       0.33   10.8   0.0    1.5  1  POTRA_2         POTRA domain, ShlB-type


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  162.8   0.0   3.4e-51   6.7e-48       1     175 [.     149     319 ..     149     320 .. 0.96
   2 ?    2.7   0.0     0.047        94      34     104 ..     362     429 ..     347     438 .. 0.66

  Alignments for each domain:
  == domain 1  score: 162.8 bits;  conditional E-value: 3.4e-51
                 -HHHHHHHHHHHTTCEEEEEESTTSSHHHHHHHHHHHHHHHS...TTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   1 tdiQaeaiplilgggdvlvaaeTGsGKTlaflipvlqivyet...kgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldn 96 
                 t+iQ++ +p +l+g+dv++ aeTGsGKTl +++p++ ++  +      +gp +li++PtreLa q+ ++++kf+   ++r  +++ggv++  q+++l++
  EEA20986.1 149 TAIQSQGWPMALSGRDVVGIAETGSGKTLTYCLPAIVHINAQpllSPGDGPIVLILAPTRELAVQIQTEISKFGRSSRIRNTCVYGGVPKGPQIRDLSR 247
                 79**********************************9998889998999***************************99*******************99 PP

                 TCSEEEEEHHHHHHHHHCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  97 gvdivvgtpgrlddllstgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlpkdvkk 175
                 gv++ ++tpgrl+d+l+ gk nl++v++lVlDEadr+ld+gf+++i++i+ q+       + +rq+++ SAT+pk+v++
  EEA20986.1 248 GVEVCIATPGRLIDMLEAGKTNLRRVTYLVLDEADRMLDMGFEPQIRKIIGQI-------RPDRQTCMWSATWPKEVRQ 319
                 9****************************************************.......35678*********99986 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.047
                 HHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEET...TSSHHHHHHHHHTT.CSEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxx.xxxxxxx RF
        DEAD  34 pvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliig...gvaardqlskldng.vdivvgt 104
                   l++++   +++++k+li + t+  a ++ + l++ + +    +l+i g   +++++  l++++ng   i+v+t
  EEA20986.1 362 KHLEKIM---EDRKNKCLIFTGTKRVADDITRFLRQDGWP----ALSIHGdkqQNERDWVLQEFKNGkSPIMVAT 429
                 3444454...478889999999999999999999888885....2333331103333333333355567777766 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       2.4   4.8e+03      31      62 ..     319     354 ..     294     361 .. 0.61
   2 !  108.0   0.0   1.6e-34   3.1e-31       3     111 .]     361     467 ..     355     467 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 2.4
                 H.HHHHHHHTTSTEEEESTTSTHHHHH....HHHHHH CS
  Helicase_C  31 k.vklllekkgikvavlhgelpqnere....eileqf 62 
                 + ++ +l+ + i+v +   +l++n+r+    e++++f
  EEA20986.1 319 QlASDFLNDF-IQVNIGSMDLSANHRItqivEVVSDF 354
                 3334444555.88888888888888884444555555 PP

  == domain 2  score: 108.0 bits;  conditional E-value: 1.6e-34
                 HHHHHHHHHHTTTTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSSHHHHH CS
  Helicase_C   3 leallellkleeeggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprnvtsyi 101
                 +++l ++  +e +++k+lif+ t++ +++++ +l++ g  ++ +hg+ +qner+ +l++f++g+s +++atdva+rGid+ ++++Vin+d+p n ++y+
  EEA20986.1 361 IKHLEKI--MEDRKNKCLIFTGTKRVADDITRFLRQDGWPALSIHGDKQQNERDWVLQEFKNGKSPIMVATDVASRGIDVRDITHVINYDYPNNSEDYV 457
                 4455555..599*************999967777888************************************************************** PP

                 HHHTTSSSTT CS
  Helicase_C 102 qriGRtgRag 111
                 +riGRtgRag
  EEA20986.1 458 HRIGRTGRAG 467
                 ********97 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.0   8.3e-07    0.0017      31     157 ..     169     300 ..     161     315 .. 0.72
   2 ?   -2.4   0.0       2.1   4.3e+03      92     113 ..     364     383 ..     337     412 .. 0.58

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 8.3e-07
                 ESTTSTHHHHH.HHHHHHH-S..........-EEEEESSHHHHHHHHHHGGGGTGG........GEEEESSS-B--.......-SEEEEEHHHHHHTH. CS
      ResIII  31 maTGtGKTlva.aklierllkkgkee.....kflflvprkslleqtleefkkflseayke....igkkvsgdkkkakekdstnkkilvttiqsldadse 119
                 ++TG+GKTl++ + +i ++  +   +      +l+l+p+++l  q ++e++kf  + + +     g++ +g + +     s   +++++t  +l   + 
  EEA20986.1 169 AETGSGKTLTYcLPAIVHINAQPLLSpgdgpIVLILAPTRELAVQIQTEISKFGRSSRIRntcvYGGVPKGPQIR---DLSRGVEVCIATPGRLIDML- 263
                 68*********87788887776555588999**********************9998765444333333333333...36778888888888888888. PP

                 .......HHHTTT-SEEEEETGGGTTS....TTTHHHHHT- CS
      ResIII 120 eeeeeseellrdrfdviiiDEaHrlgak...kswreilekf 157
                     e  +    r  +++ DEa r+ ++    ++r+i+ ++
  EEA20986.1 264 ----EAGKTNLRRVTYLVLDEADRMLDMgfePQIRKIIGQI 300
                 ....5555556666688888888877775544666666655 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 2.1
                 S-B--.......-SEEEEEHHH CS
      ResIII  92 dkkkakekdstnkkilvttiqs 113
                  +k+   +d++nk +++t +++
  EEA20986.1 364 LEKIM--EDRKNKCLIFTGTKR 383
                 22222..344444444444444 PP

>> UTP25  Utp25, U3 small nucleolar RNA-associated SSU processome protein 25
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0     0.013        26      76     102 ..     199     225 ..     197     232 .. 0.83
   2 !    9.7   0.0   0.00017      0.33     318     417 ..     359     457 ..     324     481 .. 0.86

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.013
       UTP25  76 pkvLillptreaalevvelllklleae 102
                 p vLil+ptre a+++ +++ k+  ++
  EEA20986.1 199 PIVLILAPTRELAVQIQTEISKFGRSS 225
                 77*************999998887666 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.00017
       UTP25 318 kilpqlkk.ssskssgiliyipsyfdfvrvrnylkeekvsfaaiseysskkevsraRelFfkgkkkvlLyteRlhffrRykikgvkkvilYklPenpef 415
                 k++++l+k  ++ ++++li+  +      ++++l+++    ++i+  ++++e     ++F++gk  +++ t+ +   r  +++++ +vi Y+ P+n+e 
  EEA20986.1 359 KMIKHLEKiMEDRKNKCLIFTGTKRVADDITRFLRQDGWPALSIHGDKQQNERDWVLQEFKNGKSPIMVATDVAS--RGIDVRDITHVINYDYPNNSED 455
                 4555555544477889999999988888999*****************************************885..99*****************987 PP

       UTP25 416 ys 417
                 y 
  EEA20986.1 456 YV 457
                 75 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.5   0.0    0.0098        20      13     111 ..     165     281 ..     153     305 .. 0.58
   2 !    9.0   0.0   0.00085       1.7      30      75 ..     360     405 ..     358     506 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0098
      AAA_19  13 llvtaGpGtGKTrv..lkhivallvelggvkp...eeillvaftgrAakelrerlaalgae...atTiHrlal................ldfddlltea 87 
                 ++ +a  G+GKT +  l +iv++  +   ++p     +l++a+t+  a +++++++++g++    +T+ + ++                +++ ++l   
  EEA20986.1 165 VVGIAETGSGKTLTycLPAIVHINAQPL-LSPgdgPIVLILAPTRELAVQIQTEISKFGRSsriRNTCVYGGVpkgpqirdlsrgvevcIATPGRL--- 259
                 5568899****86522444444443333.344554678999*****99999999977666655523333222255555554444444332222222... PP

      AAA_19  88 lelleeaeeekklqeeellivDEf 111
                   +le  + +++l++ ++l+ DE+
  EEA20986.1 260 IDMLE--AGKTNLRRVTYLVLDEA 281
                 22222..34555645557777776 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00085
      AAA_19  30 ivallvelggvkpeeillvaftgrAakelrerlaalgaeatTiHrl 75 
                 ++++l+++ +   +++l+ + t+r a+ ++  l++ g +a  iH+ 
  EEA20986.1 360 MIKHLEKIMEDRKNKCLIFTGTKRVADDITRFLRQDGWPALSIHGD 405
                 6899999999999********************999999****975 PP

>> ERCC3_RAD25_C  ERCC3/RAD25/XPB C-terminal helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.1   4.5e-06    0.0089      47     170 ..     359     482 ..     332     498 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 4.5e-06
  ERCC3_RAD25_C  47 racefLikyhekrgDkiivfsDnvfaLkeyakklkk.....pyiyGetseaerlkilqkfkknpkvntiflskvgDtsiDlPeanvliqisshfgs 137
                    +++++L k+ e r++k ++f+       ++++ l++       i+G+ +++er  +lq+fk+  k   ++   v+   iD+ + + +i  +    s
     EEA20986.1 359 KMIKHLEKIMEDRKNKCLIFTGTKRVADDITRFLRQdgwpaLSIHGDKQQNERDWVLQEFKNG-KSPIMVATDVASRGIDVRDITHVINYDYPNNS 453
                    5678899999999999999998888778888777752222257*****************987.556777899***************99998888 PP

  ERCC3_RAD25_C 138 rrqeaqrlGriLrakkksneeefnaffYsLvsk 170
                          r+Gr  ra +k    +  +ff +  sk
     EEA20986.1 454 E-DYVHRIGRTGRAGAK---GTAITFFTTDNSK 482
                    5.568999999998776...3445566555555 PP

>> DUF5335  Family of unknown function (DUF5335)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.1   7.1e-05      0.14      48     107 ..     319     380 ..     311     387 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 7.1e-05
     DUF5335  48 gisydpkddavevavggereeleHliakPaevy.v.eeedgelesle.iededgektlitfee 107
                 +++ d  +d ++v++g+ +   +H+i + +ev  + e+ d++++ le i +  ++k+li f  
  EEA20986.1 319 QLASDFLNDFIQVNIGSMDLSANHRITQIVEVVsDfEKRDKMIKHLEkIMEDRKNKCLI-FTG 380
                 55666679*********9999***********9635999*******8355555555555.444 PP

>> DUF2443  Protein of unknown function (DUF2443)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.4   9.8e-05      0.19      25      73 ..     320     368 ..     316     378 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 9.8e-05
                 HHT--HHHHHHHHTTSS---TTS-HHHHHHHHHHHHHHHHHHHHHHHHH CS
     DUF2443  25 lakislvdyilikrGsldmPesldvafltqideevekLkeaidaLnkik 73 
                 la   l d+i +  Gs+d+  +  ++ +  +  + ek  ++i+ L ki 
  EEA20986.1 320 LASDFLNDFIQVNIGSMDLSANHRITQIVEVVSDFEKRDKMIKHLEKIM 368
                 6666799*****************99999999999***********985 PP

>> POTRA_2  POTRA domain, ShlB-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00017      0.33      18      54 ..     363     399 ..     351     415 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00017
                 CHHHHHCCCSSSEEEHHHHHHHHHHHHHHHHHTT-TT CS
     POTRA_2  18 eleallqpylgkclgladlnqlakeltnayiekGYvt 54 
                 +le+++++ ++kcl  ++ +++a+++t +++++G++ 
  EEA20986.1 363 HLEKIMEDRKNKCLIFTGTKRVADDITRFLRQDGWPA 399
                 789999****************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (554 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       613  (0.0341904); expected 358.6 (0.02)
Passed bias filter:                      515  (0.0287244); expected 358.6 (0.02)
Passed Vit filter:                        81  (0.00451782); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.45
# Mc/sec: 3685.26
//
Query:       EEA20987.1  [L=761]
Description: pentatricopeptide repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.5e-17   62.8   0.1    2.1e-14   53.5   0.0    3.2  3  PPR_2     PPR repeat family
    8.5e-06   25.3   0.0    1.6e-05   24.3   0.0    1.4  1  PPR_long  Pentacotripeptide-repeat region of PRORP
     0.0011   19.0   0.0        0.6   10.2   0.0    2.7  2  PPR_3     Pentatricopeptide repeat domain
  ------ inclusion threshold ------
      0.029   14.6   4.3        3.9    7.9   0.0    3.7  3  PPR       PPR repeat
      0.056   13.1   0.1        0.3   10.8   0.0    2.3  3  PPR_1     PPR repeat


Domain annotation for each model (and alignments):
>> PPR_2  PPR repeat family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.5   0.0   5.8e-18   2.1e-14       3      50 .]     182     229 ..     180     229 .. 0.97
   2 !    5.7   0.0    0.0046        16       2      47 ..     259     305 ..     258     307 .. 0.88
   3 ?   -3.5   0.0       3.6   1.3e+04      16      25 ..     405     414 ..     404     418 .. 0.84

  Alignments for each domain:
  == domain 1  score: 53.5 bits;  conditional E-value: 5.8e-18
       PPR_2   3 vvtyNtlIsglckkgkveeAfklfneMkkrglePnsyTysilikglck 50 
                 + ++N l+s+++++g++  Af+++n+Mkkr   P+++Ty++++kglc+
  EEA20987.1 182 SAAWNRLLSYCFERGAPLAAFRFYNDMKKRARAPTAHTYTVMLKGLCR 229
                 579********************************************7 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.0046
       PPR_2   2 dvvtyNtlIsglckkgkveeAfklfneMkkrgl.ePnsyTysilikg 47 
                 + + y +++  + +  ++++ + +  +  + g  +P++ Ty+ ++++
  EEA20987.1 259 SHHHYHAMLEVCGTYHDMDMLWTVVGDLPELGPhKPTAQTYTLILQA 305
                 667799999999999***************7655*********9987 PP

  == domain 3  score: -3.5 bits;  conditional E-value: 3.6
       PPR_2  16 kgkveeAfkl 25 
                 +gk+e A++l
  EEA20987.1 405 QGKWEAALRL 414
                 79*****998 PP

>> PPR_long  Pentacotripeptide-repeat region of PRORP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.3   0.0   4.6e-09   1.6e-05       6     140 ..     177     311 ..     172     325 .. 0.86

  Alignments for each domain:
  == domain 1  score: 24.3 bits;  conditional E-value: 4.6e-09
                 XXX-HHHHHHHHHHHHHHHT-HHHHHHHHHHHHHSSS---HHHHHHHHH.HHHHC.HCSTTTHHHHHHHHHHHHHHHHH..TT----HHHHHHHHHHHH CS
    PPR_long   6 kkktpeselrrqldkCskekDaaaAlelydkavaegvrlaqyhynvlly.lcskaeaaseskknkalargfevfeamka..kgvspnEatvtalarlaa 101
                  k +  + ++r l  C  ++   aA+  y+++++ + + ++++y v+l  lc k+ ++      k ++ ++++++++    + v+p+   + a+  ++ 
  EEA20987.1 177 MKMETSAAWNRLLSYCFERGAPLAAFRFYNDMKKRARAPTAHTYTVMLKgLCRKSLQPGV----KPVDLAYKIYRQLLDtdSDVTPSHHHYHAMLEVCG 271
                 5556667788899999999999**************************769999966542....469999******98866899*************** PP

                 HTT-HHHHHHHHHHHHHH-.S---HHHHHHHHHHHHHTT- CS
    PPR_long 102 akedgdlafelvkemekag.vsPrLRsyaPaLaayckagd 140
                   +d d+  ++v ++ + g  +P   +y  +L+a   a d
  EEA20987.1 272 TYHDMDMLWTVVGDLPELGpHKPTAQTYTLILQAILGALD 311
                 ***************9998578*******99999876655 PP

>> PPR_3  Pentatricopeptide repeat domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.2   0.0   0.00017       0.6      18      58 ..     185     225 ..     182     229 .. 0.94
   2 !    5.7   0.0    0.0043        15       9      60 ..     254     306 ..     251     309 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00017
       PPR_3  18 YthLLtayanagnkklalevlermkkkgikPtvvtyNailg 58 
                 ++ LL+ ++  g   +a++  + mkk   +Pt  ty ++l+
  EEA20987.1 185 WNRLLSYCFERGAPLAAFRFYNDMKKRARAPTAHTYTVMLK 225
                 689***********************************997 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.0043
       PPR_3   9 kgikldvvtYthLLtayanagnkklalevlermkkkg.ikPtvvtyNailgvi 60 
                  ++ ++   Y ++L+++    + + +  v++ + + g  kPt  ty  il++i
  EEA20987.1 254 SDVTPSHHHYHAMLEVCGTYHDMDMLWTVVGDLPELGpHKPTAQTYTLILQAI 306
                 578888899************************9998569**********998 PP

>> PPR  PPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.7         3   1.1e+04      14      31 .]     112     129 ..     111     129 .. 0.84
   2 ?    7.9   0.0    0.0011       3.9       2      29 ..     184     211 ..     183     212 .. 0.95
   3 ?    6.5   0.0    0.0032        11       2      13 ..     219     230 ..     218     232 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 3
         PPR  14 GkleeAlelfkeMkekGi 31 
                 G+ ee++ l++  k kG+
  EEA20987.1 112 GNKEEVEMLMELAKGKGF 129
                 888999999999998886 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0011
         PPR   2 tynslIsgycknGkleeAlelfkeMkek 29 
                 ++n l+s +   G +  A++++++Mk++
  EEA20987.1 184 AWNRLLSYCFERGAPLAAFRFYNDMKKR 211
                 6*************************96 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.0032
         PPR   2 tynslIsgyckn 13 
                 ty+++++g+c++
  EEA20987.1 219 TYTVMLKGLCRK 230
                 9*********97 PP

>> PPR_1  PPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.1       1.9   6.8e+03      26      34 .]     201     209 ..     200     209 .. 0.91
   2 ?   10.8   0.0   8.5e-05       0.3       5      20 ..     215     230 ..     214     232 .. 0.92
   3 ?   -2.3   0.0         1   3.7e+03       4      14 ..     293     303 ..     292     305 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 1.9
                 HHHHHHHHH CS
       PPR_1  26 AfelfdeMe 34 
                 Af++ ++M+
  EEA20987.1 201 AFRFYNDMK 209
                 9*******7 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 8.5e-05
                 --HHHHHHHHHHHHHT CS
       PPR_1   5 PdvvTYNtLIdGlCka 20 
                 P++ TY+ +++GlC++
  EEA20987.1 215 PTAHTYTVMLKGLCRK 230
                 8999***********7 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 1
                 ---HHHHHHHH CS
       PPR_1   4 kPdvvTYNtLI 14 
                 kP++ TY+ ++
  EEA20987.1 293 KPTAQTYTLIL 303
                 899****9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (761 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       426  (0.0237604); expected 358.6 (0.02)
Passed bias filter:                      379  (0.0211389); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.66u 0.28s 00:00:00.94 Elapsed: 00:00:00.46
# Mc/sec: 5005.32
//
Query:       EEA20988.1  [L=306]
Description: Yip1 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-13   50.2  18.6      5e-13   49.1  18.6    1.6  1  Yip1      Yip1 domain
  ------ inclusion threshold ------
      0.034   13.9   6.0       0.05   13.4   6.0    1.3  1  DUF1282   Protein of unknown function (DUF1282)


Domain annotation for each model (and alignments):
>> Yip1  Yip1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.1  18.6   5.5e-17     5e-13      17     151 ..     159     278 ..      94     298 .. 0.76

  Alignments for each domain:
  == domain 1  score: 49.1 bits;  conditional E-value: 5.5e-17
        Yip1  17 p......ilrapdlallllalltlllgllaslnlgqtlasgeevqgltlssllgaiiggylglllgllllalllhliakllggkgsfkqtlsvvgyall 109
                         lr++dl+++l+++l l ++l +             + + ++s ++++++++++   +g ++++l ++l    lgg++sf q+++++gy+l+
  EEA20988.1 159 LqsgmseGLRDWDLWGPLIFCLLLSMFLSMR------------AHDEQSSLVFSGVFSIVW---IGEAIVTLQIKL----LGGNISFFQSVCIIGYTLF 238
                 04555666799********************............667888889999999999...************....******************* PP

        Yip1 110 Plilgaliaillllllgt.llllvgllaliWslvllylglkaa 151
                 Pl+++al+++l l+   + + + v l++++Wsl++ +  l  +
  EEA20988.1 239 PLVIAALLSALGLP---MiVRIPVYLVLIAWSLAAGVSILGGS 278
                 ********885443...24679999999999997666555444 PP

>> DUF1282  Protein of unknown function (DUF1282)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   6.0   5.6e-06      0.05      66     136 ..     196     268 ..     175     297 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 5.6e-06
     DUF1282  66 svvf.ylalgvlvlayliklmgrtydsqhsyskifafaayalvplflgglalgl..sllllvalvslllllyvv 136
                 s+vf +++  v +  ++++l  + ++++ s+ + + +++y+l+pl++++l++ l  + + ++  v l+l+++++
  EEA20988.1 196 SLVFsGVFSIVWIGEAIVTLQIKLLGGNISFFQSVCIIGYTLFPLVIAALLSALglPMIVRI-PVYLVLIAWSL 268
                 444404444666778899************99*****************9865520444444.48888888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (306 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       577  (0.0321825); expected 358.6 (0.02)
Passed bias filter:                      294  (0.016398); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.43u 0.24s 00:00:00.67 Elapsed: 00:00:00.39
# Mc/sec: 2370.22
//
Query:       EEA20989.1  [L=501]
Description: nuclear protein export protein Yrb2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      7e-19   68.3   0.0    1.6e-18   67.1   0.0    1.6  1  Ran_BP1   RanBP1 domain


Domain annotation for each model (and alignments):
>> Ran_BP1  RanBP1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.1   0.0   8.9e-23   1.6e-18       2     121 ..     373     499 ..     372     500 .. 0.83

  Alignments for each domain:
  == domain 1  score: 67.1 bits;  conditional E-value: 8.9e-23
                 ---SSTTEEEEEEEEEEEEEEETTTTEEEEEEEEEEEEEEET.........TT.TEEEEEEEETTTTEEEEEEEE-TTS-EEESTTESSEEEEEEEE-T CS
     Ran_BP1   2 vksgEEdEevlfkqraKLfrfdaekkewkeRGvGdiKilkkk.........dd.ekvRllmRrdqvlkvcaNhvitkemklkplagsdrslvwtaadaa 90 
                 +++gEE+E++ f+ +aKLf+f   +kewkeRGvG  K++ k+          + +  R++mR d+vl+v++N  i k m +  ++g +   +     a+
  EEA20989.1 373 IETGEEEEKTYFSCKAKLFHFT--NKEWKERGVGTFKVNVKEppsnaddntPKrKTARMIMRADGVLRVMLNSPIFKGMPVGEVSGEEPKGKQLN-LAS 468
                 89*******************7..589***********9654232222221223678**************************999998887755.455 PP

                 TSSSEEEEEEEEESSHHHHHHHHHHHHHHHH CS
     Ran_BP1  91 deeakleqlaikfkkkeeadefkkkfeeakk 121
                  e++k + l +++++++ a+e+++ + + +k
  EEA20989.1 469 VEDGKTVPLLLRVGNADSAKELYHVIIDLQK 499
                 5789999****************99988776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (501 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1522  (0.0848904); expected 358.6 (0.02)
Passed bias filter:                      473  (0.0263818); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.67u 0.34s 00:00:01.01 Elapsed: 00:00:00.47
# Mc/sec: 3193.38
//
Query:       EEA20990.1  [L=516]
Description: thiamin biosynthesis protein (Thi-4), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.3e-81  271.2   2.7      1e-80  270.7   2.7    1.2  1  Phos_pyr_kin  Phosphomethylpyrimidine kinase
    6.2e-53  179.7   0.1    8.9e-53  179.2   0.1    1.2  1  TENA_THI-4    TENA/THI-4/PQQC family
    1.8e-06   27.5   0.8    2.2e-05   23.9   0.8    2.1  1  PfkB          pfkB family carbohydrate kinase
    0.00038   19.9   0.5     0.0055   16.1   0.1    2.3  2  HK            Hydroxyethylthiazole kinase family
     0.0031   17.0   1.0     0.0064   16.0   1.0    1.5  1  Carb_kinase   Carbohydrate kinase
  ------ inclusion threshold ------
       0.15   11.3   0.1       0.38   10.0   0.1    1.6  1  CbiK          Cobalt chelatase (CbiK)


Domain annotation for each model (and alignments):
>> Phos_pyr_kin  Phosphomethylpyrimidine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  270.7   2.7   3.4e-84     1e-80       1     246 []      12     282 ..      12     282 .. 0.94

  Alignments for each domain:
  == domain 1  score: 270.7 bits;  conditional E-value: 3.4e-84
                   ETTSSSHHHHHHHHHHHTTEEEEEEEEEEEEEETTCEEEEEE--HHHHHHHHHHHHHTS--SEEEE-S--SHHHHHHHHHHHHHTTS.SEEEE---S CS
  Phos_pyr_kin   1 DssGGAGiqADlktfsalgvygmsvitaltaqntkgvkevhplpaelveaqleavledvkvdavKiGmlasaeiievvaeklkkykv.pvVlDPVmv 96 
                   DssGGAG++AD ++++a+gvy++++ t ltaqnt gv+++h +pa +v++q++a ledv+ d+vK+Gml+sae+++v+ae+lk+++v ++VlDPVm+
    EEA20990.1  12 DSSGGAGLEADQRVLTAHGVYSLTATTGLTAQNTLGVQDIHVVPAGFVRKQINAALEDVGADVVKLGMLSSAETVDVIAEELKRHTVkTIVLDPVMI 108
                   9**************************************************************************************9********* PP

                   SCTSSSBSSHHHHHHHHHHTGGG-SEEE-BHHHHHHHHT.......---SSHHHHHHHHHHHHHTT-SEEEEEEGGS-S...........SSEEEEE CS
  Phos_pyr_kin  97 aksgselleeeavealkeeLlplatvitPNlpEaeaLlg.......ekikteedmkeaakkllklgakaVlikGghleg...........eeavvtd 175
                   ++sgs+ll ++a++ ++++L+pl+tv+tPN+pEa+ Ll+       ++ +++++m e akk++ lg+kaVl+kGghl+            e   v+d
    EEA20990.1 109 STSGSQLLPQDAIQHVRSNLVPLTTVLTPNIPEAKLLLEnagqspvSEPQNVNEMIELAKKVQGLGSKAVLLKGGHLPFtsegvransteEARIVVD 205
                   **************************************988776555666999************************87899******98778899* PP

                   EEE......TSSEEEEEEEE----S--BTHHHHHHHHHHHHHHCTSSHHHHHHHHHHHHHHHHHCG-BSTSSS-B-- CS
  Phos_pyr_kin 176 vly......dgeeveeleaerietknthGtGCtlssaiaaelakgesleeAvkkAkeyvteaikealelgkgagpvn 246
                   vly      ++e v+  e+e++ +knthGtGC+l+saiaa+lakg++l+++v++A +yv++ ik ++++g+g gp+n
    EEA20990.1 206 VLYsaagdgEEEVVMLTETEYLRSKNTHGTGCSLASAIAANLAKGNDLQTSVRSAIKYVEAGIKLSVDMGQGSGPIN 282
                   ***8765333344566799********************************************************96 PP

>> TENA_THI-4  TENA/THI-4/PQQC family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  179.2   0.1     3e-56   8.9e-53       2     208 ..     305     514 ..     304     516 .] 0.98

  Alignments for each domain:
  == domain 1  score: 179.2 bits;  conditional E-value: 3e-56
                 HHCHHHHHHHHCSHHHHHHHTT-S-HHHHHHHHHHHHHHHHHHHHHHHHHHHC-SSHHHHHHHHHHHHHHHHCHHHHHHHHHHHTT-HHHHHCTTT--H CS
  TENA_THI-4   2 aqlrpiwkeyinHpFvkalakGtlpreqfqayviqdylylknfvrvlaiilskssdlevrrelesrivdhdgeeielhlrlaealGlsreelsktkpsp 100
                 ++++piw + ++HpFv+ l +G+lp + f++y++qdylyl++f+r+ a++ +k+ + + +   ++riv h+++e +lh  ++ ++Gl+ree+++t + +
  EEA20990.1 305 PDMKPIWHRFTHHPFVQGLGDGSLPLKNFKDYLVQDYLYLIHFARSNALASYKARTMKSI-AASARIVLHINTETALHIDYCASFGLTREEMEATPEKQ 402
                 789*********************************************************.************************************** PP

                 HHHHHHHHHHHHHCHS-HHHHHHHHHHHHHHHHHHHHHHCCHHH....S-TSCHHHHHHHHHCSHHHHHHHHHHHHHHHHHHHTSHHHHHHHHHHHHHH CS
  TENA_THI-4 101 atkayvrylldlarrgslaeavaallpclfvyqeiaerlkeklr....alegpeyyewvkeyaseefraaveeakrllerllakvsdeqleelqeiflk 195
                 a+ ay+ry+ld++++ +++++++al pcl++y  ia+rl +  +      e++ y +w+++y  e++  av+++ +lle+ + +vs++++eel +if++
  EEA20990.1 403 ACVAYSRYILDIGQSEDWLALQIALAPCLIGYGAIARRLYDDAEntvkGEENNRYWKWIENYVAEDYATAVKSGSALLEEHMHQVSPSRVEELVGIFKR 501
                 ************************************99988887788899************************************************* PP

                 HHHHHHHHHHHHH CS
  TENA_THI-4 196 alefetsfltmal 208
                 a+e+e+ f++m l
  EEA20990.1 502 ATELEIGFWDMGL 514
                 **********987 PP

>> PfkB  pfkB family carbohydrate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.8   7.5e-09   2.2e-05     151     282 ..      90     260 ..      71     264 .. 0.83

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 7.5e-09
                 HHHHHHHTTE...EEEEECESSSHH......HHHHHHHHHCTESEEEEEHHHHHHHHTSCT.......HSHHHHHHHHHHHHHTTSSEEEEEEG..... CS
        PfkB 151 laeaaknggt...fdpnlldplgaq......fkeallellaladllkpneeElealtgekl.......edieealaalhklkakgaktvvvtlG..... 228
                 ++e++++  +    dp++ +++g+q       +++ ++l++l+++l+pn  E++ l++ ++       ++++e +++++k++  g k v+ + G     
  EEA20990.1  90 AEELKRHTVKtivLDPVMISTSGSQllpqdaIQHVRSNLVPLTTVLTPNIPEAKLLLENAGqspvsepQNVNEMIELAKKVQGLGSKAVLLKGGhlpft 188
                 4455555554667899999999999996664444444567*****************************************************966666 PP

                 GGEEEEEE...............TTEEEEEEE.SSSS...-SBGTTHHHHHHHHHHHHHHTTHHHHHHHHHH CS
        PfkB 229 keGalvve...............kdgelkvpavpkvk...vvDttGAGDsfvggflaallegksleealrfa 282
                 +eG+ + +               +dge +v  + +++     +t G+G s +++++a+l++g++l++++r a
  EEA20990.1 189 SEGVRANSteearivvdvlysaaGDGEEEVVMLTETEylrSKNTHGTGCSLASAIAANLAKGNDLQTSVRSA 260
                 799999999**************8888888877666622267***************************988 PP

>> HK  Hydroxyethylthiazole kinase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.1     0.045   1.4e+02      52      92 ..      72     111 ..      62     129 .. 0.77
   2 !   16.1   0.1   1.8e-06    0.0055     164     230 ..     211     279 ..     145     291 .. 0.78

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.045
                 EEEEE-TT--HHHHHHHHHHHHHHHHTT--EEEE-TTBTTB CS
          HK  52 aLllNiGtleekaiealkaAvksakevnrPvvlDPVgvgAt 92 
                 a ++ +G l++ a  +   A + ++++ + +vlDPV ++ +
  EEA20990.1  72 ADVVKLGMLSS-AETVDVIAEELKRHTVKTIVLDPVMISTS 111
                 55788899988.333445666777778889******98865 PP

  == domain 2  score: 16.1 bits;  conditional E-value: 1.8e-06
                 EEESSEEEEEE-S-GGGG..GSTTHHHHHHHHHHHHHTTBSSHHHHHHHHHHHHHHHH..HHHHHHHTTH CS
          HK 164 vsdgkkvyklknGtellg..kitasGCllgsvvaaflavkkdkllaaveavllykvAg.keaaarsegsg 230
                   dg++++++   te+l   +  ++GC+l+s++aa la k ++l+++v + + y  Ag k  +   +gsg
  EEA20990.1 211 AGDGEEEVVMLTETEYLRskNTHGTGCSLASAIAANLA-KGNDLQTSVRSAIKYVEAGiKLSVDMGQGSG 279
                 568999888888888885225679*************9.5677788888888899999455555555554 PP

>> Carb_kinase  Carbohydrate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   1.0   2.1e-06    0.0064       1     164 [.       5     184 ..       5     202 .. 0.65

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 2.1e-06
                  EEEEE-BTTCHHHHHHHHHHHHCTT-SEEEEEESSTTTCCCCTTTTTCEECCTT..HTTTS...--SSS..-SEEEE-TT-SSSHCHHHHCHHHCCCC CS
  Carb_kinase   1 vlvigGsedytGAallaalaalrlgaglvsvateseaiavlksylpevivhpll..edeqakilekler..ldavviGpGLgrdekikklleevlekd 94 
                  vlvi+Gs+   GA+ l a   +    g+ s  +     a++   ++++ v p    + +  +i+++le   +d+v +G+ L + e+++ + ee   + 
   EEA20990.1   5 VLVIAGSDSSGGAG-LEADQRVLTAHGVYSLTATTGLTAQNTLGVQDIHVVPAGfvR-K--QINAALEDvgADVVKLGM-LSSAETVDVIAEELKRHT 97 
                  789***76655555.677777777788888887777777777777777777766322.2..455555551167777777.888888888666554444 PP

                  S-.EEEE.....GGGGGSGGGG.......TTTTSSEEEE--HHHHHHHCTTTCH.......HCCSHHHHHHHHHHHHTTEEEEESTT CS
  Carb_kinase  95 ep.lviD.....AdgLnllaqkne....lserkaeviLTPhkkEfkrLlkaivk.......keddrlelarelaqklnavvllkgek 164
                  +  +v+D      +g +ll q+      +      ++LTP++ E k Ll+ +++       + ++  ela++++   ++ vllkg +
   EEA20990.1  98 VKtIVLDpvmisTSGSQLLPQDAIqhvrSNLVPLTTVLTPNIPEAKLLLENAGQspvsepqNVNEMIELAKKVQGLGSKAVLLKGGH 184
                  334555511111555555555433444445555689*****************9999777666666777777777777889999976 PP

>> CbiK  Cobalt chelatase (CbiK)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.1   0.00013      0.38     161     208 ..      62     109 ..      53     115 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00013
                 HHHHHHHHCT-S.EEEEETTSSS-HHHHHHHHHHHT--EEEEEE-SSS CS
        CbiK 161 eldkvlkekdfkqvvvgtvegyPeveevieelkkkgikevkliPlmlv 208
                 +++  l++ + + v +g++ +  +v+ + eelk + +k++ l P+m+ 
  EEA20990.1  62 QINAALEDVGADVVKLGMLSSAETVDVIAEELKRHTVKTIVLDPVMIS 109
                 6888899999999*********************************85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (516 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       538  (0.0300073); expected 358.6 (0.02)
Passed bias filter:                      490  (0.02733); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.44
# Mc/sec: 3499.93
//
Query:       EEA20991.1  [L=1464]
Description: DNA polymerase alpha catalytic subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.2e-119  400.1   3.8   1.8e-119  399.5   3.8    1.3  1  DNA_pol_B        DNA polymerase family B
      3e-69  232.5   0.4    7.1e-69  231.3   0.4    1.7  1  zf-DNA_Pol       DNA Polymerase alpha zinc finger
    1.3e-42  146.2   0.0    2.3e-42  145.3   0.0    1.4  1  DNA_pol_B_exo1   DNA polymerase family B, exonuclease domain
    1.8e-25   88.8   7.0    1.8e-25   88.8   7.0    3.4  3  DNA_pol_alpha_N  DNA polymerase alpha subunit p180 N terminal
     0.0022   16.9   0.0     0.0064   15.4   0.0    1.7  1  DNA_pol_B_2      DNA polymerase type B, organellar and viral


Domain annotation for each model (and alignments):
>> DNA_pol_B  DNA polymerase family B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  399.5   3.8  4.9e-123  1.8e-119       2     459 .]     787    1231 ..     786    1231 .. 0.92

  Alignments for each domain:
  == domain 1  score: 399.5 bits;  conditional E-value: 4.9e-123
                  -HHHHHHS-HHHHHHHHHHHHHHHTTBE-B-...................----.--SS.-S----BE----EEESS-EEEEEETTHHHHHHHHTT- CS
   DNA_pol_B    2 plsrvledgqqirveslLlrlakeegfilpd...................rtekkgkeeegYqGatVlePkkglydkpvlvlDFaSLYPsiiqahNl 79  
                   ++r+l++++++r+e++Ll++++++++i pd                   +t+k  k++e+Y+G++V+eP+kglyd +vlv+DF+SLYPsiiq++N+
  EEA20991.1  787 SWARTLTGTRAERNEYILLHEFHRNKYICPDkysnrqlkaleekvdddddSTDK--KKKEKYKGGLVFEPEKGLYDRYVLVMDFNSLYPSIIQEFNI 881 
                  6899*****************************999999999999998644444..33336************************************ PP

                  STTTCE-HCCHCCT--BTT...TEEE-TCC-EEE-TTS---HHHHHHHHHHHHHHHHHHHHH.CS--HHHHHHHHHHHHHHHHHHHHHHHHHTSTTS CS
   DNA_pol_B   80 cyttlvaseeeakeleaedeyleveveprlvefvkksvregllpklLkdllakRkaikkelk.eekdefekalldkqQlalKvtaNsvYGftGvans 175 
                  c+tt+++s ++++e e+++            e+ ++++++g+lp+l+++l+++R+++kk +k +  ++++ al+d +Q+alK+taNs+YG++G+++s
  EEA20991.1  882 CFTTVDRSSTAENENEEQV-----------PEVPSSDQEQGILPRLIANLVTRRREVKKLMKdKRATTEQLALWDTKQMALKLTANSMYGCLGYTQS 967 
                  ***********99877654...........34445889************************6555556889************************* PP

                  TT--HHHHHHHHHHHHHHHHHHHHHHHHT...SSGGGT-SS.....T-EEEEEBSSEEEEE-S-SSHHHHHHHHHHHHHHHHT.TSTTT--EEEEEE CS
   DNA_pol_B  176 rlpclalAasvTtiGRemLektkelvekkaellskllalpeeaeeeklkviYGDTDSvfielkvkdveellkigkelaeevseklfkkplklefekv 272 
                  r+++ +lA + T +GRe+L +tk+l e+k                 +l+viYGDTDSv+i++++++++++lk+g+e+++ v+e ++k  l++++++v
  EEA20991.1  968 RFYARPLAMLTTFKGREILRSTKDLAESK-----------------QLRVIYGDTDSVMINTNMDTISDALKVGEEFKASVNE-RYKL-LEIDIDNV 1045
                  ***************************99.................9************************************.9998.******** PP

                  EEEEEEEETTEEEEEEEEESSTTS..EEEEESSGGGSTTS-HHHHHHHHHHHHHHSSS....S-HHHHHHHHHHHHHHHHHHHHTT-S-GGGG-EEE CS
   DNA_pol_B  273 ykkllLisKKkYaglkvektskan..klliKGvdlvRrdncklvkevikkvlelllkdeteersleeglealksilkdvleeleenkvplekfvlsk 367 
                  + +llL++KKkYa++ +++ + +   kl++KG+d+ Rr+ c+l+kev+k++l+++l+     ++ e++l++++++l dv+++++e k+p++k+v+ +
  EEA20991.1 1046 FRRLLLHAKKKYAAINMTEIDGKYvdKLEVKGLDMKRREYCALSKEVSKRLLDEILSG----EDSEVVLNKVHDYLRDVTAQMKEYKIPVQKYVIYT 1138
                  *****************9877655669*******************************....*********************************** PP

                  EESS.CCCS.SGCCSHHHHHHHHHHHHCSS---TTCEEEEEEBETSS.....SS-GGGTEEEH.HHHHH.CCSEB-HHHHHH.TTHHHHHHHHTTS CS
   DNA_pol_B  368 elskepeny.ksknlphlevakrlkkrneeapevgdrisYvivekkkevkkknllaseraedp.eyvle.knlpidieyYls.qllkevarlleai 459 
                  +lsk pe+y +++++p ++va r  +r ++++++ d+i+Y++++ ++  +++nl   +r +   ++++  ++l+ dieyYl  q++++++rl+++i
  EEA20991.1 1139 KLSKRPEEYpNKESMPPAQVALREIAR-GKTIRPNDVIAYIVTSGDS--ETANLPPPKRSYTLqDVMKPdSELKPDIEYYLLkQIFPPIERLCAPI 1231
                  *********999**************9.799**************98..58888888888888555554467********999*********9876 PP

>> zf-DNA_Pol  DNA Polymerase alpha zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  231.3   0.4     2e-72   7.1e-69       1     185 []    1270    1459 ..    1270    1459 .. 0.97

  Alignments for each domain:
  == domain 1  score: 231.3 bits;  conditional E-value: 2e-72
                  XXXX-TTTTTT---EEEE-TTT--EEEE-SSS--S.SEEEETTEEEET..TT--B--HHHHHHHHHHHHHHHHHHHHH--EEES-TTT--EES---S CS
  zf-DNA_Pol    1 sqisdeerFkdceplelrCpsCkeefefegvfesaeeekvtasglrCsnesCkaslstaslvnqlelairkhiskYYegwlvCddptCgnrTrqlsv 97  
                  sqi+d+ rF+++++l+lrC++C+e++ feg+ +s   ++++++g+ C+ne+C + +st+s+v+q+e++ir++++kYYegwlvCdd++CgnrTrq+sv
  EEA20991.1 1270 SQIPDSIRFEHSARLSLRCRHCGESSVFEGLSSSP--RMCSPHGVVCPNEACANVFSTISIVAQVESQIRAQTAKYYEGWLVCDDSSCGNRTRQMSV 1364
                  79*****************************9988..8*********************************************************** PP

                  STTB-S.......T---BEEESS-HHHHHHHHHHHHHHT-HHHHHTT-S--S.--HHHHHHHHHHTHHHHHHHHHHHHHHHHC-XXXXXXXXXXX CS
  zf-DNA_Pol   98 ygkrCla......gCkgrmrkeysekqLYnQLlYfeslfdvekalkklkkee.ekkekvealaeknrerlktlkevvdkyleksgyrwVdlksLF 185 
                  yg+rCl+      gC grm++ey+ekq+YnQLlYf+ l+dv+ka++ + ke+  +k++++alae nr r+ t+k vvd yl+k+g++wV++++LF
  EEA20991.1 1365 YGHRCLGprgraeGCLGRMNYEYTEKQMYNQLLYFAGLWDVDKAKSVAAKEAsDAKDNIHALAEYNRARFATVKGVVDGYLKKCGRQWVEMDTLF 1459
                  ******99999988******************************998877776899**************************************9 PP

>> DNA_pol_B_exo1  DNA polymerase family B, exonuclease domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.3   0.0   6.5e-46   2.3e-42       4     337 .]     377     720 ..     374     720 .. 0.84

  Alignments for each domain:
  == domain 1  score: 145.3 bits;  conditional E-value: 6.5e-46
                     TTSEEEEEEEE---EEEEEES....SCGGHHHHHHHHHHHCCTTCCCEE....EEEEEECCCCEECCTSSCCHHC....EEEEEESSTCHHHHHH CS
  DNA_pol_B_exo1   4 egksvcvnvfgfkpyfYceap....dgkeleevkeelkelyeelskkvt....kivkvelvlkkslygyekkpvp....ylkvsvsnpnelkkir 86 
                       +s++v+v ++ + +++ ++    ++   ++ +  ++++yee +  +t    ++ k++++++k  y++e +++p    ylk+ +++ +++++++
      EEA20991.1 377 SYVSSFVKVDNILRKLFFLPRenrvKNGHVTDEEVDMEDVYEEVDGMMTklkvGMHKIKPCTRK--YAFELPNIPkegdYLKLLYPYDKPVLPMD 469
                     57899************99995555333444555556667777776666886666666666665..55555555555****************** PP

                     HHHHHCCCCCCCCSSS--HHHHHHHHCTS-TTCEEEEETEEEEGCC--C-.SEEEEEETTTSCEETTTCC...S-EEEEEEEEEETEETTSEETT CS
  DNA_pol_B_exo1  87 kelspleeivdvyeydvdylerflidnkivgfgwysvkkylvraegkisncdveidcdvddliakpkese...pplrvlsFDIeckskkgkfpda 178
                     ++    e++++v+++++  +e+f++ + ++g++w+++ +++++a +++s+c++e+++++++ i+   +se   ppl+++s ++++        ++
      EEA20991.1 470 TT---GETFSHVFGTNTALFEQFVLWKHVMGPCWLKIGEADFSAATNASWCKFECQVSKPNTITTIPDSEletPPLTLMSLSFRT------QLNV 555
                     99...69******************************************************************************......8899 PP

                     TT..--EEEEEEEE.CCTC...SS.SEE...EEEEECCCTSS----EE--SSTCSTTEEEE.EESSHHHHHHHHHHHHHHH--SEEEESSTTTTH CS
  DNA_pol_B_exo1 179 ensedpiiqIscvl.dglg..ekepear...klftlrecaseeeedfeltpkpeypgvkvl.efdsEkelLqaflefikqydPdvitgYNidnFD 266
                     ++++++i   s+ + ++++  e++p+++   k ft+   +  +++   l+   + ++  v+  +++E  lL++fl ++ ++dPd+i+g+ +++ D
      EEA20991.1 556 KENKQEILVASARIyENVSlpETTPPEKmpcKTFTVMRPS-GTSYPIGLEAEVK-KQRGVYmLEKNEQFLLSKFLALFERMDPDIIMGHQLQEVD 648
                     999***********66666766666666888666666665.3444333322222.222444689******************************* PP

                     HHHHHHHHHHCCTCCHCG.SCCS..CTCEECCCCESEEEEEECEEEETTSEEEEHHHHHHHHSSSS..G-SHHHH CS
  DNA_pol_B_exo1 267 lpYilnRakelykvklsklgrln..kggrskvseigfskqarekvkisgrihlDlyrvvkrklklp..sYkLnav 337
                     l  +lnR+ke +++ +s++grl+  ++++++++  gf    ++   i+gr+++Dl + + ++l  +  s++L ++
      EEA20991.1 649 LGILLNRMKEKKTPGWSRVGRLKrtEWPKNFNRGGGFF---ADRHLIAGRMMCDLANDMGKSLMVKcqSWTLTEM 720
                     **************************************...9********************777777****886 PP

>> DNA_pol_alpha_N  DNA polymerase alpha subunit p180 N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.8   7.0   5.1e-29   1.8e-25       1      65 [.       9      73 ..       9      74 .. 0.98
   2 ?    1.8   0.2      0.07   2.5e+02      17      31 ..     406     421 ..     396     423 .. 0.62
   3 ?   -3.5   0.0       3.1   1.1e+04      19      31 ..     561     574 ..     552     574 .. 0.67

  Alignments for each domain:
  == domain 1  score: 88.8 bits;  conditional E-value: 5.1e-29
  DNA_pol_alpha_N  1 LekLkaaReggkkakdeyeveeeeriYdeVdeeeYkklvrkrleeddFvvDDdgegYvddGeedw 65
                     L++Lka+R++gkk++++yeve++ +iYdeVdee Ykk+vrkrl+eddFvvDD+gegY+ddG+e w
       EEA20991.1  9 LAELKALRASGKKRLSTYEVEDQGSIYDEVDEEGYKKVVRKRLDEDDFVVDDNGEGYADDGREVW 73
                     89*************************************************************99 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.07
  DNA_pol_alpha_N  17 eyeve.eeeriYdeVd 31 
                       ++ e + e++Y+eVd
       EEA20991.1 406 VTDEEvDMEDVYEEVD 421
                      223344899******9 PP

  == domain 3  score: -3.5 bits;  conditional E-value: 3.1
  DNA_pol_alpha_N  19 eve.eeeriYdeVd 31 
                      e+    +riY+ V+
       EEA20991.1 561 EILvASARIYENVS 574
                      44457899***995 PP

>> DNA_pol_B_2  DNA polymerase type B, organellar and viral
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   1.8e-06    0.0064     205     253 ..     838     886 ..     817     905 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 1.8e-06
  DNA_pol_B_2 205 ldkyiRkayrGGrc.ypsvlgiyeeniyvyDvnSlYPsamthypmPygkp 253
                   dk+ ++ y GG + +p  +g y+  + v D+nSlYPs+  ++ + +++ 
   EEA20991.1 838 TDKKKKEKYKGGLVfEPE-KGLYDRYVLVMDFNSLYPSIIQEFNICFTTV 886
                  56777999******8887.********************99987766665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1464 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       920  (0.0513135); expected 358.6 (0.02)
Passed bias filter:                      501  (0.0279436); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.95u 0.31s 00:00:01.26 Elapsed: 00:00:00.54
# Mc/sec: 8220.29
//
Query:       EEA20992.1  [L=1289]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.9e-37  127.0   0.0    1.5e-36  126.2   0.0    1.3  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    3.5e-09   36.9   0.0    9.8e-09   35.4   0.0    1.7  1  rve              Integrase core domain
    8.8e-09   35.1   0.1    1.7e-08   34.2   0.1    1.4  1  gag_pre-integrs  GAG-pre-integrase domain
  ------ inclusion threshold ------
      0.017   15.3   0.0      0.086   13.1   0.0    2.2  1  TetR_C_31        Tetracyclin repressor-like, C-terminal domai
       0.11   12.4   0.0       0.29   11.0   0.0    1.7  1  Flg_hook         Flagellar hook-length control protein FliK


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  126.2   0.0   4.3e-40   1.5e-36      10     230 ..     819    1036 ..     810    1045 .. 0.91

  Alignments for each domain:
  == domain 1  score: 126.2 bits;  conditional E-value: 4.3e-40
       RVT_2   10 kdrkaigsrWvftkkkddl.kevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeeelvvhqldvdsafLnaeldeevyvkqPpGfei 105 
                  ++++ +   Wv+  k d++ + vk karlva+G  q  + d  +++a  +   s r l++++a  +l +  +d   af+na++dee+y+k PpG+  
  EEA20992.1  819 REKQILDCMWVYVYKADKKgRLVKCKARLVARG-DQEKEDDMRDTYAATLAARSFRTLMSICARFGLEIKGFDAVNAFVNAKIDEEMYMKMPPGYRK 914 
                  567778899******9999899***********.688899*******************************************************87 PP

       RVT_2  106 dreeekvykLnkslyGlkqapllWnekidkvLkklgferseaesGlyvrgtgegklivalyvddlliagsdik..iledvkkelakkfklkdlgkvs 200 
                      + +y++nk++yGl+++pllW+e+++ +Lk+lgf+  + e    +r+     +i+  yvdd+++a ++ +  + +++  +l kk+++    +++
  EEA20992.1  915 R---GLIYRINKAIYGLRRSPLLWQEELTGTLKDLGFKAVPHEPCCMLRS----GIILFFYVDDIVLAYKKEReaEANEIMARLRKKYNITGGEDLD 1004
                  6...9********************************************9....799**********98876511578999**************** PP

       RVT_2  201 kfLGieiaq..eaggiklsladyiakvvkkfe 230 
                   fLG+ i++  e   i ls+a yi k++k ++
  EEA20992.1 1005 WFLGMRIVRdrEKKLIWLSQATYIDKIAKLVD 1036
                  *******9855667899**********98665 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.4   0.0   2.7e-12   9.8e-09      24     118 ..     254     350 ..     231     350 .. 0.92

  Alignments for each domain:
  == domain 1  score: 35.4 bits;  conditional E-value: 2.7e-12
         rve  24 ayllvvvddfsrlilaealsdemdastvlalleravarfggve...pervlsDngseytskafrefladlgirvsftrpgrpqdnGkvErfhrtlkde 118
                   l  ++d +s++++ ++l+++ ++  vl++l+  +a+++++    p+r+ +Dn  +++   ++++l + ++++ +++p+   +nG +Er  r++kd+
  EEA20992.1 254 RTLMLITDRYSGYTWDFYLTSH-TTLEVLDMLKWLFAYLKKQYnltPKRMEMDNEITMVIPGVADWLTEQHVKLLPSAPYAQAQNGGAERVGRIIKDK 350
                 568899****************.******************88****************************************************985 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.2   0.1   4.8e-12   1.7e-08      19      66 ..     163     215 ..     149     216 .. 0.75

  Alignments for each domain:
  == domain 1  score: 34.2 bits;  conditional E-value: 4.8e-12
  gag_pre-integrs  19 kn.kssinlWHrRLGHpsfsrlkkLfkkgl...lpglkisk.sevCeaCqlgK 66 
                      k+ k s+++WH RLGHp+ + +++L++      + gl+++    +CeaC+ +K
       EEA20992.1 163 KErKASAKRWHARLGHPGPQVIQHLANATKgvrVTGLSKGPtTVQCEACARAK 215
                      324899********************9544446677776543559******99 PP

>> TetR_C_31  Tetracyclin repressor-like, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   2.4e-05     0.086      47     102 ..     161     221 ..     155     223 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2.4e-05
                 HHHHHHHHHHHHHHHHCSS-HHHHHHHHHHHHHHHHHHHHHSG.TS-H.......HHHHHHHHH CS
   TetR_C_31  47 lrralrealaallaalGlpdpeeaarllvaaldGllldrLagp.aadp.......raevrellr 102
                 +r +  + + +++a+lG+p+p+  +++l  a  G+ +  L  + +  +       ra + +++r
  EEA20992.1 161 ARKERKASAKRWHARLGHPGPQ-VIQHLANATKGVRVTGLSKGpT--TvqceacaRAKIQRMVR 221
                 5677888999************.*****************99941..23563334555555555 PP

>> Flg_hook  Flagellar hook-length control protein FliK
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   8.1e-05      0.29      34      66 ..    1175    1207 ..    1167    1224 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 8.1e-05
                  ETTEEEEEEEE-SCHHHHHHHHTHHHHHHHHHC CS
    Flg_hook   34 rggqlsvqltaenpetrelLeqnlprLreaLaa 66  
                  r +  ++++  +n++t+ lLe+++prLr+ L+ 
  EEA20992.1 1175 RFQTPTLHVYCDNKQTLGLLEKDAPRLRTKLRH 1207
                  55566899**********************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1289 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       640  (0.0356964); expected 358.6 (0.02)
Passed bias filter:                      573  (0.0319594); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.86u 0.33s 00:00:01.19 Elapsed: 00:00:00.49
# Mc/sec: 7846.33
//
Query:       EEA20993.1  [L=473]
Description: hypothetical protein PMAA_047990 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
       0.16   12.1   0.0        0.3   11.2   0.0    1.5  1  DUF5012          Domain of unknown function (DUF5012)
       0.67    9.7   7.1        1.6    8.5   6.6    2.1  2  Sulfotransfer_4  Sulfotransferase domain
        9.9    6.3  10.0         21    5.3   1.1    3.2  3  Myb_DNA-bind_5   Myb/SANT-like DNA-binding domain


Domain annotation for each model (and alignments):
>> DUF5012  Domain of unknown function (DUF5012)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0     5e-05       0.3      63     113 ..     208     257 ..     173     264 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 5e-05
                 TSS-EEEEEE-TTS-EEEEEEE-TTS----SEEEEEEEETTTTEEEEEEEE CS
     DUF5012  63 ayamkGyiqlkndnsitllsssvkgwddsldaleegkldPetgevswkaey 113
                 +ya + +i lk+  + + l++ + +wdd l+  e  k+  +t +++w  ++
  EEA20993.1 208 DYAAV-FILLKQARTTKDLEAWIVKWDDVLTRAERKKMSIATNTIEWADKF 257
                 55554.67899999*********************************8766 PP

>> Sulfotransfer_4  Sulfotransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   6.6   0.00027       1.6      38     151 ..     155     279 ..     130     439 .. 0.71
   2 ?   -1.5   0.0      0.31   1.8e+03      97     124 ..     409     436 ..     405     456 .. 0.63

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00027
  Sulfotransfer_4  38 sdlkewaealeakkegk....kpitredfdkllggydavvdvpaalfaeelleayPdakvIl....teRdpekWlksmkktllalrsetlsrll 123
                      +d++++ ++++++ + +       +  d++k++++ ++ +  p+  +++++   y    ++l    t++d e+W  +++ +l ++ ++++s + 
       EEA20993.1 155 RDVDKVFNWMKKTVHPSylkmCVSNTPDWRKAYRNLKSHLSQPQSDVYRKISSDYAAVFILLkqarTTKDLEAWIVKWDDVLTRAERKKMSIAT 248
                      344444444444444445556667788****************************8655555999999******************99877555 PP

  Sulfotransfer_4 124 al...ldpllellaklvellralvrrlfgag 151
                      +    +d++ ++ + l + + ++++  f+++
       EEA20993.1 249 NTiewADKFFDAIDFLDHSWITTFKVHFHEK 279
                      5500044444333333333434444444433 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.31
  Sulfotransfer_4  97 eRdpekWlksmkktllalrsetlsrlla 124
                      ++  ++W ++ ++++ +l++++ + +l+
       EEA20993.1 409 QERAKEWTEKNTNMIDELVKHHEQLTLS 436
                      4455566666666666666665555544 PP

>> Myb_DNA-bind_5  Myb/SANT-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.1      0.17     1e+03      60      70 ..     182     192 ..     175     198 .. 0.87
   2 ?    5.3   1.1    0.0035        21      51      76 ..     218     243 ..     190     245 .. 0.79
   3 ?    5.2   0.4    0.0038        23       1      35 [.     411     445 ..     411     450 .. 0.75

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.17
  Myb_DNA-bind_5  60 elkkkwedlkr 70 
                     +++k +++lk+
      EEA20993.1 182 DWRKAYRNLKS 192
                     8********97 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0035
  Myb_DNA-bind_5  51 lgsveRtaeelkkkwedlkrraKkkl 76 
                     ++ +++++e++  kw+d  +ra +k 
      EEA20993.1 218 QARTTKDLEAWIVKWDDVLTRAERKK 243
                     56789************999987764 PP

  == domain 3  score: 5.2 bits;  conditional E-value: 0.0038
  Myb_DNA-bind_5   1 RkknfseeEkevLvelveknksilegkksdaatnk 35 
                     R+k ++e+ ++++ elv+ ++++  +  +++   +
      EEA20993.1 411 RAKEWTEKNTNMIDELVKHHEQLTLSANKEHPRSR 445
                     89***********9999998887666555544444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (473 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1069  (0.0596241); expected 358.6 (0.02)
Passed bias filter:                      519  (0.0289475); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.66u 0.31s 00:00:00.97 Elapsed: 00:00:00.52
# Mc/sec: 2761.76
//
Query:       EEA20994.1  [L=555]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      0.002   18.5   1.1         32    5.1   0.0    5.1  5  LRR_4     Leucine Rich repeats (2 copies)
     0.0048   17.5   0.6      0.016   15.8   0.0    2.2  2  HHH_5     Helix-hairpin-helix domain


Domain annotation for each model (and alignments):
>> LRR_4  Leucine Rich repeats (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.1   0.0    0.0035        32       8      32 ..     182     204 ..     181     210 .. 0.82
   2 ?    2.0   0.1     0.035   3.1e+02      22      38 ..     278     290 ..     255     316 .. 0.70
   3 ?    0.6   0.0     0.092   8.3e+02       2       9 ..     339     346 ..     330     375 .. 0.75
   4 !    4.1   0.0    0.0073        65       3      30 ..     395     429 ..     393     438 .. 0.63
   5 ?   -3.9   0.0         2   1.8e+04      22      32 ..     448     458 ..     446     459 .. 0.73

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0035
                 --SS---E-S-HHH-TT--EEE-.- CS
       LRR_4   8 LsnNqltdiplleklpnLkeLdLsg 32 
                 Ls+N l+   +   lp L++L++++
  EEA20994.1 182 LSGNALKQ--WAIHLPRLQTLYIWN 204
                 89999999..7557********965 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.035
                 -TT--EEE-.-S----- CS
       LRR_4  22 lpnLkeLdLsgNnlitd 38 
                 l++L++L L  N  + +
  EEA20994.1 278 LDSLTKLVL-TN--L-S 290
                 666666666.44..2.2 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.092
                 S--EEE-- CS
       LRR_4   2 nLevLdLs 9  
                 nL++L L+
  EEA20994.1 339 NLRHLQLR 346
                 55555554 PP

  == domain 4  score: 4.1 bits;  conditional E-value: 0.0073
                 --EEE--SS-...--.E-S-HH...H-TT--EEE- CS
       LRR_4   3 LevLdLsnNq...lt.diplle...klpnLkeLdL 30 
                 L++L L+  +   ++ + +ll+   kl+ L+eLdL
  EEA20994.1 395 LRSLILQRKRhavVQnEASLLQaicKLTELRELDL 429
                 56666664444555544444556668********9 PP

  == domain 5  score: -3.9 bits;  conditional E-value: 2
                 -TT--EEE-.- CS
       LRR_4  22 lpnLkeLdLsg 32 
                 l++L+ +++sg
  EEA20994.1 448 LTKLERFSVSG 458
                 78888887765 PP

>> HHH_5  Helix-hairpin-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   1.8e-06     0.016       3      48 ..     259     305 ..     258     311 .. 0.84
   2 ?   -3.2   0.1       1.6   1.4e+04      18      38 ..     414     433 ..     413     434 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 1.8e-06
                 HHHTSTT--HHHHHHHHTTT--SHHHH..HHS-HHHHHTSTTS-HHHH CS
       HHH_5   3 eLlsvsGiGpktAlallsaGiesvedl..aaadveeLakipGiGkktA 48 
                 e++s+s iGp+t+lal s+  +s+ +l   ++++e++a +p +G+ +A
  EEA20994.1 259 EVISLSFIGPRTILALGSH-LDSLTKLvlTNLSIEAIAHLPTLGPPKA 305
                 689****************.9999877325789*******99987554 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 1.6
                 HHTTT--SHHHHHHS-HHHHH CS
       HHH_5  18 llsaGiesvedlaaadveeLa 38 
                 ll a i+ + +l ++d +e++
  EEA20994.1 414 LLQA-ICKLTELRELDLKEVS 433
                 6777.8888999999988876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (555 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       329  (0.0183502); expected 358.6 (0.02)
Passed bias filter:                      286  (0.0159518); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.23s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 3980.21
//
Query:       EEA20995.1  [L=458]
Description: DNA repair protein rad9, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.5e-52  177.3   0.6    4.2e-52  177.1   0.6    1.1  1  Rad9      Rad9
    8.9e-08   31.5   1.2    6.5e-07   28.7   0.6    2.4  2  Rad1      Repair protein Rad1/Rec1/Rad17


Domain annotation for each model (and alignments):
>> Rad9  Rad9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  177.1   0.6   4.7e-56   4.2e-52       4     249 ..      19     288 ..      16     289 .. 0.94

  Alignments for each domain:
  == domain 1  score: 177.1 bits;  conditional E-value: 4.7e-56
        Rad9   4 alqclsrigdelyleisedglelrtvnssrSayalvtlk.ksfFdky...........ekevseqirckilvKsvlsvfr....slsakektvekvkis 86 
                 al cls++++ + +e++ d+l+l+t+n +++aya++ l  ++fF ky            ++  +++ c++ +K++lsvf+        k++ ve+++++
  EEA20995.1  19 ALVCLSKFNESVSIEAEYDLLRLSTLNTAKTAYASFVLDsSKFFFKYsfsargaqqssGQRYVDKFACQMYIKALLSVFKgragESRDKQTAVERCDVE 117
                 789***********************************6268***********999887888999***************555422347789******* PP

        Rad9  87 i....dekksrlivqllCkhgvkkthkisledseslkavfdkettpsklriksrvLsdllehfsssleeitielakervllksyeeeekdn....kkal 177
                 +    de ++rl +q+ C +gv k +k+++e    ++a fd+++++++++i++++L+++++hfs + e++ i +  ++ +++s++++  d     k+++
  EEA20995.1 118 LhdspDEVECRLHIQMICGQGVVKSYKLTYEPVSVQHALFDQSRVQNQWVIQAKILREIIDHFSPTAEQLDIYPDAGKAIFTSFTNKISDGkeilKQPV 216
                 *9999999*****************************************************************************999888777789** PP

        Rad9 178 stelsideeeFeqyqlaedveitlslkefkallvfaeslsaslslafdeaGkPllltikklslleakfilaT 249
                 +t + id+++Fe++++  + ++ +++k+fka++v a+++++ +++ + ++ +Pl l+  +   ++ +f l T
  EEA20995.1 217 HTSVAIDRKDFEEFTVRDGLHVAINVKDFKAAVVHADTMKTAITARYTRPCRPLQLAYVSEDGIDSEFTLMT 288
                 ***********************************************************999******9988 PP

>> Rad1  Repair protein Rad1/Rec1/Rad17
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.7   0.6   7.3e-11   6.5e-07       2     196 ..       6     193 ..       5     222 .. 0.82
   2 ?   -0.2   0.0     0.047   4.2e+02     110     149 ..     248     288 ..     194     301 .. 0.70

  Alignments for each domain:
  == domain 1  score: 28.7 bits;  conditional E-value: 7.3e-11
        Rad1   2 fsAtlsnvseLatlLksiafkd.kalvqissdGlkfiv.ednrvlqaqafldk.alFtsYtfenaqddedeedeeedsvsfevsLsallecLnifgknd 97 
                 fs + s + +L+++L +++ ++ +++++++ d l++++ + +++  a+ +ld+ ++F +Y+f ++ +++++ ++  d+   ++ ++all+ ++   +++
  EEA20995.1   6 FSLKPSALLQLHDALVCLSKFNeSVSIEAEYDLLRLSTlNTAKTAYASFVLDSsKFFFKYSFSARGAQQSSGQRYVDKFACQMYIKALLSVFKGRAGES 104
                 5666678889********999857************87358999*******862699*****99999999999999999*********99998555555 PP

        Rad1  98 ssskessssraskvasssakatscklsYkgeGsPLvliLee.....agvtttcelsTyepeedldleldrqevvlkvilkselLhsalteLdatskklk 191
                  +++              ++ ++c  + ++  ++    L       +gv+ + +l Tyep +     +d+++v+++ ++++++L++++  ++ t+++l 
  EEA20995.1 105 RDKQ--------------TAVERCDVELHDSPDEVECRLHIqmicgQGVVKSYKL-TYEPVSVQHALFDQSRVQNQWVIQAKILREIIDHFSPTAEQLD 188
                 5543..............4455677777776666665555522545666666665.79999************************************** PP

        Rad1 192 ilass 196
                 i+  +
  EEA20995.1 189 IYPDA 193
                 98655 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.047
        Rad1 110 kvasssakatscklsYkgeGsPLvliLee.agvtttcelsT 149
                  v+++++++t ++  Y+ +  PL l     +g+  +  l T
  EEA20995.1 248 AVVHADTMKTAITARYTRPCRPLQLAYVSeDGIDSEFTLMT 288
                 33778888888888888888888886443377766666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (458 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       427  (0.0238162); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.25s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 2960.69
//
Query:       EEA20996.1  [L=456]
Description: alpha-tubulin suppressor protein Aats1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-27   95.2  18.7      8e-08   32.8   0.0    7.8  6  RCC1      Regulator of chromosome condensation (RCC1) repeat
    1.5e-21   75.6  19.4    5.3e-07   29.3   0.1    6.4  6  RCC1_2    Regulator of chromosome condensation (RCC1) repeat
  ------ inclusion threshold ------
        2.7    8.3   4.4        3.4    8.0   0.0    3.0  4  DUF4213   Putative heavy-metal chelation


Domain annotation for each model (and alignments):
>> RCC1  Regulator of chromosome condensation (RCC1) repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.8   0.0   1.3e-11     8e-08       3      50 .]       3      72 ..       2      72 .. 0.78
   2 !    6.2   0.1    0.0027        16       1      17 [.      75      91 ..      75     147 .. 0.75
   3 !    6.6   1.5     0.002        12       6      50 .]     165     225 ..     164     225 .. 0.57
   4 !   25.1   0.1   3.4e-09     2e-05       1      48 [.     228     280 ..     228     281 .. 0.85
   5 !   19.5   0.0   1.9e-07    0.0011       4      50 .]     348     391 ..     345     391 .. 0.76
   6 !   10.4   0.3   0.00013       0.8       6      47 ..     400     450 ..     397     453 .. 0.73

  Alignments for each domain:
  == domain 1  score: 32.8 bits;  conditional E-value: 1.3e-11
                EEEEEE--GGGTTSSSS---EEEEEE-....................GGGTTS..-EEEEEEETTEEEEE CS
        RCC1  3 rVysWGrndyGqLGlgttesvlvPtkv....................eglsgn..rvvkvacGddhtval 50
                +V++ G+n  GqLG+g++++v+ Pt+                     +g++g+  +v+ ++cG++ht+ l
  EEA20996.1  3 KVFALGSNGSGQLGIGHRDDVSEPTEClfcddaivtnqqqqqqqqtaNGSDGTerKVKRISCGGNHTLIL 72
                69**********************77766666666655555555444555444*9************975 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.0027
                TTEEEEEE--GGGTTSS CS
        RCC1  1 dGrVysWGrndyGqLGl 17
                dG Vy+ G n++ ++G 
  EEA20996.1 75 DGVVYAAGLNEDLRCGV 91
                8***************8 PP

  == domain 3  score: 6.6 bits;  conditional E-value: 0.002
                 EEE--GGGTTSSSS-......--E.......EE........EEE-GGGTTS.-EEEEEEETTEEEEE CS
        RCC1   6 sWGrndyGqLGlgtt......esv.......lv........Ptkveglsgn.rvvkvacGddhtval 50 
                 s G +d+G LGlg+        ++       +v        P      +++ r+ ++++G +h+va+
  EEA20996.1 165 SLGTGDKGELGLGSGlrttssTNNtvdgaliDVddylltdfP------PATtRIEAISSGMNHVVAI 225
                 679999999999777654443222233333311332323332......2224999999999999987 PP

  == domain 4  score: 25.1 bits;  conditional E-value: 3.4e-09
                 TTEEEEEE--GGGTTSSSS-....--EEEEEE-GGGTTS.-EEEEEEETTEEE CS
        RCC1   1 dGrVysWGrndyGqLGlgtt....esvlvPtkveglsgn.rvvkvacGddhtv 48 
                 +G+Vy+WG + +GqL + ++    + v+ P+++ + +      +v+cG  +t+
  EEA20996.1 228 NGEVYGWGASRKGQLSNDSKsvgrKVVWAPVRIDLTDMGvVPRSVSCGREFTF 280
                 69***************999876455588****88766678889********9 PP

  == domain 5  score: 19.5 bits;  conditional E-value: 1.9e-07
                 EEEEE--GGGTTSSSS---EEEEEE-GGGTTS-EEEEEEETTEEEEE CS
        RCC1   4 VysWGrndyGqLGlgttesvlvPtkveglsgnrvvkvacGddhtval 50 
                 V +WGrnd+GqLG   + s    ++ ++ + + v +  +G+ h va+
  EEA20996.1 348 VIAWGRNDRGQLGVHEKSSA---VRESMVRWESVAQFMAGSEHAVAV 391
                 779***********888555...333333334899999999999986 PP

  == domain 6  score: 10.4 bits;  conditional E-value: 0.00013
                 EEE--GGGTTSSSS---E.........EEEEE-GGGTTS-EEEEEEETTEE CS
        RCC1   6 sWGrndyGqLGlgttesv.........lvPtkveglsgnrvvkvacGddht 47 
                 s+G++++G +G  t+e+           +P +v   ++ +vv v +G+  +
  EEA20996.1 400 SCGWGEHGNCGPDTDERGnvkgrlsriQLPAEVLYDDQAKVVRVGAGCATS 450
                 89**********888444223434434559999887777*****9998765 PP

>> RCC1_2  Regulator of chromosome condensation (RCC1) repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.0     0.032   1.9e+02      19      30 .]       3      14 ..       2      14 .. 0.91
   2 !   29.3   0.1   8.9e-11   5.3e-07       1      28 [.      59      86 ..      59      90 .. 0.94
   3 !   27.0   0.2   4.5e-10   2.7e-06       1      30 []     212     241 ..     212     241 .. 0.96
   4 ?    0.8   0.0     0.077   4.6e+02       3      12 ..     271     280 ..     270     281 .. 0.84
   5 !    9.7   0.3   0.00012      0.74      10      30 .]     336     358 ..     333     358 .. 0.76
   6 !   14.8   1.8     3e-06     0.018       2      29 ..     376     407 ..     375     410 .. 0.79

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.032
      RCC1_2 19 eVlcWGsNsdGQ 30
                +V++ GsN++GQ
  EEA20996.1  3 KVFALGSNGSGQ 14
                68999******9 PP

  == domain 2  score: 29.3 bits;  conditional E-value: 8.9e-11
      RCC1_2  1 VksvsaGdyHscaLtedGeVlcWGsNsd 28
                Vk +s+G++H+++L+edG V++ G N+d
  EEA20996.1 59 VKRISCGGNHTLILLEDGVVYAAGLNED 86
                899***********************85 PP

  == domain 3  score: 27.0 bits;  conditional E-value: 4.5e-10
      RCC1_2   1 VksvsaGdyHscaLtedGeVlcWGsNsdGQ 30 
                 ++++s+G +H +a++++GeV++WG    GQ
  EEA20996.1 212 IEAISSGMNHVVAILSNGEVYGWGASRKGQ 241
                 789*********************999999 PP

  == domain 4  score: 0.8 bits;  conditional E-value: 0.077
      RCC1_2   3 svsaGdyHsc 12 
                 svs+G+ +++
  EEA20996.1 271 SVSCGREFTF 280
                 9****99886 PP

  == domain 5  score: 9.7 bits;  conditional E-value: 0.00012
      RCC1_2  10 HscaLted.Ge.VlcWGsNsdGQ 30 
                 H + L+++ ++ V +WG+N++GQ
  EEA20996.1 336 HGICLHDTlDKsVIAWGRNDRGQ 358
                 666666654446**********9 PP

  == domain 6  score: 14.8 bits;  conditional E-value: 3e-06
      RCC1_2   2 ksvs...aGdyHscaLtedGe.VlcWGsNsdG 29 
                 +sv+   aG+ H++a+++d++ V+++G+ ++G
  EEA20996.1 376 ESVAqfmAGSEHAVAVLSDNKtVVSCGWGEHG 407
                 56666658*******7776666******9887 PP

>> DUF4213  Putative heavy-metal chelation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   0.0   0.00057       3.4      10      38 ..      55      94 ..      47     121 .. 0.81
   2 ?    0.5   0.0      0.12   7.1e+02      10      38 ..     208     237 ..     199     277 .. 0.76
   3 ?   -3.0   0.0       1.6   9.3e+03      18      34 ..     382     402 ..     376     422 .. 0.56
   4 ?   -3.6   0.1       2.3   1.4e+04      11      27 ..     437     453 ..     430     455 .. 0.59

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00057
     DUF4213 10 edltVedvviGlnwtlVelsdg...........gaGlAyt 38
                 +++V+++ +G n tl+ l+dg           ++G+++ 
  EEA20996.1 55 TERKVKRISCGGNHTLILLEDGvvyaaglnedlRCGVCWA 94
                5899*****************7777666777788888876 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.12
     DUF4213  10 edltVedvviGlnwtlVelsdg.gaGlAyt 38 
                  ++++e +  G n +++ ls+g   G  ++
  EEA20996.1 208 ATTRIEAISSGMNHVVAILSNGeVYGWGAS 237
                 67899************9999963344444 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 1.6
     DUF4213  18 viGlnwtlVelsdg....gaG 34 
                 + G    +++lsd+    ++G
  EEA20996.1 382 MAGSEHAVAVLSDNktvvSCG 402
                 555544444444432444444 PP

  == domain 4  score: -3.6 bits;  conditional E-value: 2.3
     DUF4213  11 dltVedvviGlnwtlVe 27 
                 +++V +v  G   ++V+
  EEA20996.1 437 QAKVVRVGAGCATSWVV 453
                 56666666665544444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (456 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       466  (0.0259914); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.24s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 3219.75
//
Query:       EEA20997.1  [L=666]
Description: MFS phosphate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-22   80.5  20.1    7.1e-20   71.3  20.1    2.1  1  Sugar_tr  Sugar (and other) transporter
    2.7e-05   23.3  34.3    0.00082   18.4  10.8    2.8  3  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.3  20.1   7.9e-24   7.1e-20       8     452 .]     101     540 ..      95     540 .. 0.74

  Alignments for each domain:
  == domain 1  score: 71.3 bits;  conditional E-value: 7.9e-24
                 HHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTT.SS-TGG CS
    Sugar_tr   8 ggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgk.nsvevl 105
                 g ll+gY ++ ++++++ll+ a+  ++s++++ ++    ++ +++ + ++G ++G++++g+lgd++GR+++l+  a+++++g ++  aa g  ++ +v+
  EEA20997.1 101 GLLLEGYVLFSVSTVQSLLADAFPDCWSRHQT-CN--VNWINALTYLEIAGIMVGQILVGYLGDMIGRRWGLIQDATIMFVGLLMLTAAYGVtENGWVI 196
                 4499**************************98.55..258889999999*********************************99999998767888888 PP

                 GGG..HHHHHHHHHHHHHHHHHHHHTTS..........-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-...........TTHHHHHHHCCHHHH CS
    Sugar_tr 106 ivg..RvlvGigvGlasvlvPmyisEiA..........pkklRgalvslyqlaitfGilvaaifglglnktsn...........adgwrillglqlvpa 181
                 + +   ++  igvG+++ ++ +   E+A             +Rg+ v+   l+  +G+++ +++   l  +             a          + ++
  EEA20997.1 197 CYAwsLFFYSIGVGGEYPMTATSGMENAvgsgristreDRLHRGRKVVSAFLMQGWGQFINQGLLILLLLIFHhgsgsppyskvA----------AQWT 285
                 888668999*************************99887889********************99888755444444455555442..........4444 PP

                 HHHHHHGGGS---HHHH.HHTT-HH.HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH.....HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTT CS
    Sugar_tr 182 llllilllflPESPryl.vekgkee.eakevlaklrgeedadrelaeekdsleaeqeeekaswkellssktvrqrlligvvlqifqqltGinaimyysp 278
                   +++++  +     +l + +  +  +a + l+ +++++ ++ + +e ++ +                  +++ + l +    +f + +    +  + +
  EEA20997.1 286 YRVSFAIPAVG--TLWLtYYRAYHMkAASKQLQAIKKKASVTGYDVESFRLTL-----------------KYFGPRLFATSFGWFANDVFFYGNKLFQT 365
                 44444444444..2333122222222555555554444444444444444444.................44446666666666654444444444445 PP

                 THHHHSS-THH.....HHHHHHHHHHHHHHHHHHHHHHHH..S-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHH CS
    Sugar_tr 279 tifenlglsks.....llvtiivgvvnfvatfvaiflvdr..fGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfalgwgpv 370
                 ++++ +  +++      l +++ + v  v    a fl+d    GR+ +  +G+++++i+fv+ g   + + ++      ++ ++++l  ++ ++g+++v
  EEA20997.1 366 QFINVILPNEKslmpnWLYNLLNIGVSLVGYYLASFLIDNkfYGRKWMQQVGFLMCFILFVVPG-FRYNYYTSL-EHIKAFQAMYFLSSFFNQFGPNCV 462
                 5544444444484444444555555555555555588875448********************9.333333332.1234555666666667789***** PP

                 HHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 371 pwvlvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                  +++++E fp  +R++a  +++a+  l  ++ +++  ++  +      f ++  + +++++++++ +p t g++l+e+e+ +
  EEA20997.1 463 TFLVAAECFPAPIRASAHGFSAAMGKLGALIAAIVSSYTSAQQR----FHIWPWFGLAGMLVTYLWLPDTTGLDLKEQERRW 540
                 ******************************99999999988888....99999*************************9987 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   9.3   1.2e-06     0.011     243     329 ..     137     224 ..      62     253 .. 0.68
   2 !    9.7  15.1   4.1e-05      0.37      34     136 ..     135     256 ..     108     373 .. 0.56
   3 !   18.4  10.8   9.1e-08   0.00082      36     165 ..     382     525 ..     361     571 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.2e-06
       MFS_1 243 lllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllll...vlvliGfglgfvfpsllalasdla 329
                 ++ a+++l ++++++  +++l+g+l d +grr+ l+    ++++++l+l  +   +++ ++++   +l+++++g+g  +p+ ++  +++a
  EEA20997.1 137 WINALTYLEIAGIMV--GQILVGYLGDMIGRRWGLIQDATIMFVGLLMLTAAYGVTENGWVICyawSLFFYSIGVGGEYPMTATSGMENA 224
                 333332233333322..3677777777777777777777777777777766666667777777776777777777777777776666666 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 4.1e-05
       MFS_1  34 igllltlyal...gaavaslplGrlsdrfGrrrvlllglllfalglllllfa.....sslw.lllvlrvlqGlgagalfpagaaliadwfpke...... 117
                 ++++ +l +l   g +v+++++G+l+d +Grr+ l+  ++++++gll+l+ a     +++    +++ ++ ++g g+ +p+ a+   + + ++      
  EEA20997.1 135 VNWINALTYLeiaGIMVGQILVGYLGDMIGRRWGLIQDATIMFVGLLMLTAAygvteNGWViCYAWSLFFYSIGVGGEYPMTATSGMENAVGSgristr 233
                 455555544444466777777777777777777666666666666444442233455555555666677777777777776666555555554455555 PP

       MFS_1 118 ....ergraigllsagfslGail 136
                     +rgr +  + ++ + G  +
  EEA20997.1 234 edrlHRGRKVVSAFLMQGWGQFI 256
                 55555555555555555555555 PP

  == domain 3  score: 18.4 bits;  conditional E-value: 9.1e-08
       MFS_1  36 llltlyalga.avaslplGrlsdr..fGrrrvlllglllfalglllllf.....a..sslwlllvlrvlqGlgagal.fpagaaliadwfpkeergrai 123
                 +l+ l  +g  +v+ +++++l+d+  +Gr+++  +g+l+ ++ ++++ f     +   ++ ++ ++ +l++++  ++ + +   ++a+ fp + r++a 
  EEA20997.1 382 WLYNLLNIGVsLVGYYLASFLIDNkfYGRKWMQQVGFLMCFILFVVPGFrynyyTslEHIKAFQAMYFLSSFFNQFGpNCVTFLVAAECFPAPIRASAH 480
                 555555554438999999*****6668************9999899997545442455566788888888888733314555667899*********** PP

       MFS_1 124 gllsagfslGailgpllggllasslg...Wravfyilaivsllaf 165
                 g+ +a+  lGa+++++++++ +++     W++  ++  +v+ l++
  EEA20997.1 481 GFSAAMGKLGALIAAIVSSYTSAQQRfhiWPWFGLAGMLVTYLWL 525
                 **********************55555566666555555555552 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (666 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       652  (0.0363657); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.68u 0.27s 00:00:00.95 Elapsed: 00:00:00.45
# Mc/sec: 4427.86
//
Query:       EEA20998.1  [L=630]
Description: serine/threonine protein kinase (YPK1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.4e-70  236.4   0.0    4.4e-70  236.1   0.0    1.1  1  Pkinase        Protein kinase domain
    2.9e-34  118.5   0.0    4.2e-34  118.0   0.0    1.1  1  Pkinase_Tyr    Protein tyrosine kinase
    3.9e-10   40.3   0.1      1e-09   39.0   0.1    1.8  1  Pkinase_C      Protein kinase C terminal domain
    3.3e-07   29.6   0.1    5.1e-07   29.0   0.1    1.2  1  Haspin_kinase  Haspin like kinase domain
     0.0074   15.6   0.0      0.013   14.8   0.0    1.4  1  Kinase-like    Kinase-like
  ------ inclusion threshold ------
      0.057   13.7   0.0       0.12   12.7   0.0    1.4  1  C2             C2 domain
      0.058   13.0   0.1       0.52    9.9   0.0    2.1  2  FTA2           Kinetochore Sim4 complex subunit FTA2
        0.1   11.9   0.0       0.17   11.2   0.0    1.2  1  Dcc1           Sister chromatid cohesion protein Dcc1


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  236.1   0.0     2e-73   4.4e-70       1     264 []     287     544 ..     287     544 .. 0.95

  Alignments for each domain:
  == domain 1  score: 236.1 bits;  conditional E-value: 2e-73
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHH.HHHHHHHHHHHHHSCTTB--EEEEEEESSEEEEEEE--TTEBHHHHHHHHSS--HH CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkke.kkvlrEikilkklkhpnivrlyevfeekdelylvleyveggeladllerkgslsee 98 
                 +e l+ +G+GsfGkV+++++k+t++i+A+K+++k ++ +++e  ++l+E ++l++++ p+iv l+ +f+++++lylvl +v+ggel+++l+r++ ++ +
  EEA20998.1 287 FELLKVVGRGSFGKVMQVRKKDTKRIYALKTLRKAHIISRSEvAHTLAERSVLAQINNPFIVPLKFSFQSPEKLYLVLAFVNGGELFHHLQREQRFDIN 385
                 577899*********************************9999******************************************************** PP

                 HHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCS.BCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHHHHHSS-S CS
     Pkinase  99 eakkiakqilegleylHskgiiHrDlKpeNiLidekgelKitDFGlakelesssk.ltsfvgtseYlAPEvlkeneyskkvDvWslGvilyelltgkpp 196
                 +a+++++++l +le lH  ++i+rDlKpeNiL+d +g++ ++DFGl+k   ++++ +++f+gt+eYlAPE+l +n+y+k+vD W+lGv+lye+ltg pp
  EEA20998.1 386 RARFYTAELLCALECLHGFKVIYRDLKPENILLDYTGHIALCDFGLCKLDMKDEDrTNTFCGTPEYLAPELLLGNGYTKSVDFWTLGVLLYEMLTGLPP 484
                 ************************************************75555555******************************************* PP

                 TTTSSHHHHHHHHHHTHHHHHHHCTSHH...HHHTTS-HHHHHHHHHHT-SSGCCSTT...HHHHHTSGGG CS
     Pkinase 197 fsgekgkekvekeldqlekilkilgetkeklpeaseiseeakdllkkllkkdpkkRlt...aeellqhpyl 264
                 f++e+++e ++k++++            +++p ++ ++  a+dll++ll++dp++Rl+   a+e+++h+++
  EEA20998.1 485 FYDENTNEMYKKIVQE-----------PLTFPSHDIVPAAARDLLTRLLDRDPQRRLGangAAEIKAHHFF 544
                 **88888877777666...........6899**************************97778899999887 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.0   0.0   1.9e-37   4.2e-34       2     250 ..     288     530 ..     287     535 .. 0.91

  Alignments for each domain:
  == domain 1  score: 118.0 bits;  conditional E-value: 1.9e-37
                  EEEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTS..SHHHHHHHHHHHHHHHTS-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHTCT CS
  Pkinase_Tyr   2 elgkklGeGafGkVvegtlkgekekkevkVavKtlkeea..teeekeelleeakimkklkhpnivkllgvctkeepllivteyvkgGdLlkfLrkkek 97 
                  el k +G+G+fGkV++ + k    +++   a+Ktl++ +  +++e ++ l e +++ ++++p iv l     + e+l++v+ +v+gG+L ++L+++  
   EEA20998.1 288 ELLKVVGRGSFGKVMQVRKK----DTKRIYALKTLRKAHiiSRSEVAHTLAERSVLAQINNPFIVPLKFSFQSPEKLYLVLAFVNGGELFHHLQRE-- 379
                  67899**********99888....889999*****765422677789999*********************************************8.. PP

                  TTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEETTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSEEEHHHHHHHHHHHH CS
  Pkinase_Tyr  98 ekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsenkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekkftsksDvWsfGvll 195
                  +++++++   +++++ +++e L+  k++ rdl   N+Ll+ + ++ ++DfGL++  +kd++ +  ++     +++apE l  + +t++ D W  Gvll
   EEA20998.1 380 QRFDINRARFYTAELLCALECLHGFKVIYRDLKPENILLDYTGHIALCDFGLCKLDMKDEDRT--NTFCGTPEYLAPELLLGNGYTKSVDFWTLGVLL 475
                  99****************************************************885555443..34455679************************* PP

                  HHHHTTSSGTTTTSHHHHHHHHH.HTTEES-BBTTSBHHHHHHHHHHT-SSGGGS- CS
  Pkinase_Tyr 196 wEiftlgespypglkneevlekl.kegkrlekpekcpeelyelmkkcweedpeeRp 250
                  +E++t g  p+ + +++e+++k+ +e    +  + +p++  +l+++ +++dp++R 
   EEA20998.1 476 YEMLT-GLPPFYDENTNEMYKKIvQEPLTFPSHDIVPAAARDLLTRLLDRDPQRRL 530
                  *****.****9999999999998688889999999******************995 PP

>> Pkinase_C  Protein kinase C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.0   0.1   4.5e-13     1e-09       4      46 .]     568     606 ..     565     606 .. 0.96

  Alignments for each domain:
  == domain 1  score: 39.0 bits;  conditional E-value: 4.5e-13
   Pkinase_C   4 deDtsNFDpeFTeedprdtppddmpagspltssvqenFrGFtY 46 
                 ++Dt NFDpeFT e p d+ ++    g  l++ +q++F G++Y
  EEA20998.1 568 ALDTENFDPEFTGEMPVDSVVE----GNALSQTMQDQFAGWSY 606
                 78********************....89**************9 PP

>> Haspin_kinase  Haspin like kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.0   0.1   2.3e-10   5.1e-07     143     260 ..     311     438 ..     273     448 .. 0.79

  Alignments for each domain:
  == domain 1  score: 29.0 bits;  conditional E-value: 2.3e-10
  Haspin_kinase 143 kelslkelkslklvkgtypglllllqdkvlkek........pdfyseqqlflvlllkdkGtdLeevklkswkqalsifwqivkiLyvaEtkfeFE. 229
                    ++  lk l++ +++  +   ++l  ++ +++ +          f+s ++l+lvl + ++G+   +++ ++  ++++  + +++ L + E    F  
     EEA20998.1 311 RIYALKTLRKAHIISRSEVAHTLAERSVLAQINnpfivplkFSFQSPEKLYLVLAFVNGGELFHHLQREQRFDINRARFYTAELLCALECLHGFKv 406
                    44555667777777666444444444444444467777766889999******************************************8655543 PP

  Haspin_kinase 230 .HRdLhldniLvdknlnvtlidlklsRle.sse 260
                      RdL+ +niL+d ++++ l+d+ l++l  + +
     EEA20998.1 407 iYRDLKPENILLDYTGHIALCDFGLCKLDmK-D 438
                    39*************************9952.3 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   5.8e-06     0.013     149     288 .]     390     529 ..     366     529 .. 0.71

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 5.8e-06
  Kinase-like 149 lTlqlirlaanLqakglvhgkftvdnllldekgglmlggftaLvragtkv..vlsevekgfaPpEllgsrggytrknktkmthkldaWqlGlviyriw 244
                   T++l+     L+   ++  +++++n+lld  g + l +f+ L +   k   + ++ +     pE l+            +t ++d W+lG+  y + 
   EEA20998.1 390 YTAELLCALECLHGFKVIYRDLKPENILLDYTGHIALCDFG-LCKLDMKDedRTNTFC---GTPEYLAPELL----LGNGYTKSVDFWTLGVLLYEML 479
                  4677777778899999************************8.4444444300334444...34555555444....2236788**************9 PP

  Kinase-like 245 clklPl.tlateeakeew.....kfklckkipekvkaLlkkfLqlsqedR 288
                      P+ ++ t+e+ ++       f     +p + + Ll ++L ++ ++R
   EEA20998.1 480 TGLPPFyDENTNEMYKKIvqeplTFPSHDIVPAAARDLLTRLLDRDPQRR 529
                  99888745666666666577776777777889999999999998887776 PP

>> C2  C2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   5.2e-05      0.12      24      86 ..     149     219 ..     129     234 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 5.2e-05
                 EEEEEEEECEEEEEE-SCSSSSSSEE...EEEEEEEESCHTTSEEEEEEEEECS.......SSTEEEEEEEEE CS
          C2  24 pyvkvsldgkqkakTrviknslnPvW...nekftfevaeleeakLeveVfdndr.......lskddfiGkvei 86 
                 py+ +++d++q++   v  + +nP W   n  f+f+v+   +++L ++++ ++         s+d f+G ++ 
  EEA20998.1 149 PYALLDFDKNQVFVDAVSGTPENPLWagdNTAFKFDVSR--QTELSIQIYLRNPaarpgvgRSEDIFLGATKT 219
                 999999*9********877779****9999*********..89999999987776677754455558887765 PP

>> FTA2  Kinetochore Sim4 complex subunit FTA2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0   0.00023      0.52      20      58 ..     282     323 ..     276     348 .. 0.76
   2 ?    0.2   0.0      0.22   4.9e+02     178     204 ..     391     417 ..     378     431 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00023
        FTA2  20 ae.kdiefleyLgkglhsiVlkvkirgk..eYALKlFrflea 58 
                  + +d+e+l+++g+g  + V++v+ ++   +YALK  r+ + 
  EEA20998.1 282 MKlEDFELLKVVGRGSFGKVMQVRKKDTkrIYALKTLRKAHI 323
                 44589******************9987556*****9888754 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.22
        FTA2 178 lpkllrdlkklhklgIvvrDlkeenyi 204
                 + +ll  l+ lh   ++ rDlk+en++
  EEA20998.1 391 TAELLCALECLHGFKVIYRDLKPENIL 417
                 678899999***************986 PP

>> Dcc1  Sister chromatid cohesion protein Dcc1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   7.5e-05      0.17      89     170 ..     215     356 ..     200     380 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 7.5e-05
                 EEEEE--S-.--TT-...-EE-S-SSTHHHHH...TSS-S..........................................................- CS
        Dcc1  89 ElkeiaprldklkelLrepeYdgeeeeeeedaksaeekek..........................................................y 129
                   ++++prl++  +++++p+ +++++++++ +++++ ++                                                           y
  EEA20998.1 215 GATKTQPRLQETTTYVENPKLSKKDNQKAAAEQEKNVGQLgaewldlqfgtgsikiglsfvenrvhsmkledfellkvvgrgsfgkvmqvrkkdtkriY 313
                 5689999999999999999999999998877766554444999******************************************************** PP

                 SHHHHHHTSSS-HHHHHHHHHHCTEE.EE.TTEEEEE-HHHHH CS
        Dcc1 130 tleeLlenvqaSeaElkkaLkelgal.ei.dGrlrllspsyls 170
                  l+ L+++  +S++E+ + L+e+++l +i + ++++l++s++s
  EEA20998.1 314 ALKTLRKAHIISRSEVAHTLAERSVLaQInNPFIVPLKFSFQS 356
                 **************************99944577788888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (630 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       516  (0.0287802); expected 358.6 (0.02)
Passed bias filter:                      473  (0.0263818); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.65u 0.30s 00:00:00.95 Elapsed: 00:00:00.46
# Mc/sec: 4147.60
//
Query:       EEA20999.1  [L=519]
Description: SAGA complex subunit (Ada2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.8e-10   39.4   4.1    7.6e-10   38.5   4.1    1.5  1  ZZ               Zinc finger, ZZ type
    5.1e-10   39.4   0.0    1.3e-09   38.1   0.0    1.7  1  Myb_DNA-binding  Myb-like DNA-binding domain
    7.7e-09   35.8   0.7    2.6e-08   34.1   0.0    2.2  3  SWIRM            SWIRM domain
  ------ inclusion threshold ------
       0.04   13.7   1.7       0.15   11.9   1.7    2.1  1  SHOCT            Short C-terminal domain


Domain annotation for each model (and alignments):
>> ZZ  Zinc finger, ZZ type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.5   4.1   1.7e-13   7.6e-10       3      44 ..      17      61 ..      16      62 .. 0.92

  Alignments for each domain:
  == domain 1  score: 38.5 bits;  conditional E-value: 1.7e-13
                S-EE-TTT-S..EESSEEEES..SSSS-EE-HHHHHH..H---SS CS
          ZZ  3 kkytCdgCseapligvRyhcl..rcsdYDLCqsCfst.hkagkhk 44
                 ky+Cd+Cs + +  vR +c+  +c++YDLC++Cf +   +++h 
  EEA20999.1 17 TKYHCDVCSVDITSTVRISCAhpSCPEYDLCVPCFAAgESSKTHD 61
                58******************9667*************99999996 PP

>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.1   0.0   2.9e-13   1.3e-09       2      43 ..      80     123 ..      79     125 .. 0.94

  Alignments for each domain:
  == domain 1  score: 38.1 bits;  conditional E-value: 2.9e-13
                      SSSBHHHHHHHHHHHHHHT.TCHHHHHHHHT.SS-HHHHHHHHH CS
  Myb_DNA-binding   2 gkWteeEdelLleavkkhG.nrWkkIaerlg.gRtekqcrsrwr 43 
                        W ++E++lLle+ + +G ++W+ Ia+++g  R+++++r+++ 
       EEA20999.1  80 EDWGADEELLLLEGAEIYGlGSWADIADHIGgYRSKEEVRDHYI 123
                      57*****************************66*********95 PP

>> SWIRM  SWIRM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0       1.4   6.3e+03      49      58 ..     146     155 ..     116     171 .. 0.52
   2 ?   -2.7   0.1       1.7   7.8e+03      34      47 ..     264     277 ..     236     299 .. 0.68
   3 !   34.1   0.0   5.8e-12   2.6e-08       7      87 ..     447     516 ..     445     517 .. 0.93

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 1.4
       SWIRM  49 keyltvteaq 58 
                 + +++++e+q
  EEA20999.1 146 QDEISKEEFQ 155
                 4556666663 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 1.7
       SWIRM  34 lkiRnkiialyren 47 
                 l++R+ i ++ +++
  EEA20999.1 264 LEYRKNIAQEKKRT 277
                 45555555555544 PP

  == domain 3  score: 34.1 bits;  conditional E-value: 5.8e-12
       SWIRM   7 dpdslhpiEkellselfngkdktpeeYlkiRnkiialyrenpkeyltvteaqkalkrrrltgidvnllsrihefLerwGlI 87 
                 d + l+++E+el+ ++      +p+ Yl i++ ++++  ++ +  l++++a+  +k      id++++ ri++f+ + G+I
  EEA20999.1 447 DLHLLTKEEVELCNSVH----VQPKPYLVIKEALLKEAMKQ-NGTLKKKDARTICK------IDAAKAGRIFDFMVHSGWI 516
                 568899**********9....9******************8.777******77777......9*****************9 PP

>> SHOCT  Short C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   1.7   3.3e-05      0.15      14      26 ..     148     160 ..     146     160 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 3.3e-05
       SHOCT  14 eIteEEFeakKak 26 
                 eI++EEF+a+K++
  EEA20999.1 148 EISKEEFQARKKR 160
                 9**********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (519 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1271  (0.0708907); expected 358.6 (0.02)
Passed bias filter:                      559  (0.0311785); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.45
# Mc/sec: 3473.90
//
Query:       EEA21000.1  [L=737]
Description: mannitol-1-phosphate dehydrogenase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      5e-45  153.9   0.1    8.7e-45  153.1   0.1    1.3  1  Mannitol_dh_C    Mannitol dehydrogenase C-terminal domain
    2.5e-26   92.7   0.0    6.7e-25   88.1   0.0    2.4  2  DIOX_N           non-haem dioxygenase in morphine synthesis N
    5.8e-21   74.9   0.0    1.5e-20   73.5   0.0    1.7  1  2OG-FeII_Oxy     2OG-Fe(II) oxygenase superfamily
    3.4e-18   66.3   0.2    1.4e-17   64.2   0.0    2.0  2  Mannitol_dh      Mannitol dehydrogenase Rossmann domain
  ------ inclusion threshold ------
       0.01   15.7   0.5      0.054   13.4   0.0    2.3  2  3HCDH_N          3-hydroxyacyl-CoA dehydrogenase, NAD binding
      0.012   15.2   0.2      0.032   13.8   0.2    1.8  1  UDPG_MGDP_dh_N   UDP-glucose/GDP-mannose dehydrogenase family
       0.02   15.2   1.6          2    8.7   0.1    2.8  2  TrkA_N           TrkA-N domain
        0.1   11.8   0.2       0.18   11.0   0.2    1.4  1  Pyr_redox_2      Pyridine nucleotide-disulphide oxidoreductas
       0.16   11.8   0.0       0.33   10.8   0.0    1.4  1  Methyltransf_23  Methyltransferase domain


Domain annotation for each model (and alignments):
>> Mannitol_dh_C  Mannitol dehydrogenase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  153.1   0.1   4.4e-48   8.7e-45       4     241 ..     154     372 ..     151     376 .. 0.94

  Alignments for each domain:
  == domain 1  score: 153.1 bits;  conditional E-value: 4.4e-48
  Mannitol_dh_C   4 gfpntmVDRIvpaatddelakleeelgveDplavtvEpFiqWviednfvkgrpelelvgvelvedvepyeerKlriLNggHaalaylgalaGyqti 99 
                     f n+++DRIvp             +  + +l+v  E+F++W +e++ +    + +++ ++ v+++epy+erKl+++N+gHa+ ay g+ aG +ti
     EEA21000.1 154 RFANSAIDRIVPT------------QPEHAGLNVRIEKFYEWAVEQTPFGEYGHPDISAIHWVDHLEPYIERKLFTVNTGHATAAYYGYKAGKKTI 237
                    599*********4............5567789***************999999******************************************* PP

  Mannitol_dh_C 100 heamkdeeiraivkkllteevapllkkv..deqdleeYadkiieRFsNpyikdtvervaldGsqklpkrilpslrrlikagtlpellalgvalwir 193
                    heam++e+i ++v+++l e+  ++++k+   eq+ +eY + ii+R sNpy++d verv++      p r+l+  +r+i   +  +l ++g +++ +
     EEA21000.1 238 HEAMAEETIHKAVHAALDETASLIISKHeiTEQEQKEYVKTIISRISNPYLEDVVERVGRA-----PLRKLSRKERFIG--PAAQLAERG-MKFDA 325
                    ****************************9999*****************************.....************9..*********.***** PP

  Mannitol_dh_C 194 ylegvaeggnyie.keDpqleelqeaallakervkavlaekeileedla 241
                    +l  ++++ ++++ k D++++el++  +l+++  +++ ++ ++le d +
     EEA21000.1 326 LLGSIEKALQFQNvKGDDESTELAK--ILSEKTAAEATQQITGLETDHP 372
                    ********9987615699*******..9999999999999999998875 PP

>> DIOX_N  non-haem dioxygenase in morphine synthesis N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.0      0.18   3.6e+02      15      48 ..     243     276 ..     234     283 .. 0.85
   2 !   88.1   0.0   3.3e-28   6.7e-25       1     118 []     409     531 ..     409     531 .. 0.92

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.18
      DIOX_N  15 raavaeqlreAcrevGffyvvnhgvpeelidelf 48 
                 ++ + +++++A+ e+  ++++ h ++e++ +e  
  EEA21000.1 243 EETIHKAVHAALDETASLIISKHEITEQEQKEYV 276
                 567899********************99988765 PP

  == domain 2  score: 88.1 bits;  conditional E-value: 3.3e-28
      DIOX_N   1 iPvidlspl..sddedraavaeqlreAcrevGffyvvnhgvpeelidelfeaareFFalPeeeKekl..akspsfrGysrlgeektdgkkldwkesfdl 95 
                 iP+id+s++  +d+++ a++a+++ + +++ Gf+++++hg+ +el+ +l++ ++ FFalP+e+K  l   +sp+ r ++++ge+++++++ d ke+f +
  EEA21000.1 409 IPIIDISDYlsKDESATASIASSISSTAQSPGFLQITGHGIAPELTIKLLDRLKAFFALPLETKTTLhrNNSPALREFEAVGEQSLEKGVMDSKEGFMI 507
                 9*******995555889**************************************************766678************************** PP

      DIOX_N  96 gtelp.eddpagkplegpnqwPee 118
                 g+e+  e++++ + l+gpnqwP+e
  EEA21000.1 508 GPEWLvENAKNARFLQGPNQWPAE 531
                 ***97344458899********86 PP

>> 2OG-FeII_Oxy  2OG-Fe(II) oxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.5   0.0   7.6e-24   1.5e-20       4      99 ..     582     690 ..     579     692 .. 0.90

  Alignments for each domain:
  == domain 1  score: 73.5 bits;  conditional E-value: 7.6e-24
                   EEEEEEE-S------..---EEEEEESSSEEEEEEE-.........TT---EEEE.TE.EEE----TTEEEEEE-HHHHHHTTS-S----EEE-.-- CS
  2OG-FeII_Oxy   4 llvlnyypphpdpev..ilglgahtdaslltillqdd.........vgglevfkd.gk.wlrvppvdnslivniGdallflsngryksvlHrVl.pv 86 
                   +++++ ypp ++ ++  + g+gahtd + lt+llqd+         +gglevf+   + w  v+pv ++++vniGd+l+ ++n++y+s+lHrV+ pv
    EEA21000.1 582 MCRAHRYPPTTQEMSkkSRGIGAHTDFGALTLLLQDKdlftdfriiLGGLEVFHRpTEtWHPVQPVVGAFVVNIGDMLERWTNNKYTSTLHRVTsPV 678
                   6777778*****998889**********************************9554667***********************************555 PP

                   -GTGSEEEEEEEE CS
  2OG-FeII_Oxy  87 negerRvsiayfi 99 
                      e R+s+a+f 
    EEA21000.1 679 SN-EYRYSVAFFN 690
                   55.66******96 PP

>> Mannitol_dh  Mannitol dehydrogenase Rossmann domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.2   0.0   7.1e-21   1.4e-17       2     150 ..       4     125 ..       3     126 .. 0.95
   2 ?   -1.2   0.0         1   2.1e+03      45      88 ..     253     283 ..     218     315 .. 0.57

  Alignments for each domain:
  == domain 1  score: 64.2 bits;  conditional E-value: 7.1e-21
                  EEEEES-SHHHHHTHHHHHHHHTT--TT-EEEEEE-STTHHHHHHHTTTT-EEEEE-SSS---EEEE--EEEEEEGGG-HHHHHHHHTSTT--EEEE- CS
  Mannitol_dh   2 rivhfGaGnfhRahqayiddLlaeegldwgivevnlrevdareaLkaqdelyvviekgeeskearlvgsvnavlsveedlealieamaePeirivslt 99 
                  ++++fG Gn++R+   ++ + l+e+g+++ +++v +++ +    L++ ++++v+ ++ ee+++ +++++ +a+ s++++  ++++++a   +++v+ +
   EEA21000.1   4 KAIQFGGGNIGRG---FVAEFLHESGYEVVFIDVVPQVIES---LNKNKSYEVTEIS-EEGEKTKTITNYRALSSKTQE-PEVVKEIAT--ADVVTCA 91 
                  79***********...99999*****************999...***********99.999****************99.9********..******* PP

                  --TTTBETTTEB-TTSHHHHHHHH-TTHHHHHHHHHHHTT----EEEE-SS CS
  Mannitol_dh 100 vtekGidatgeletdlpaiaadlakpellvealkrrraaglkpltiisCdn 150
                  v++          + l+ ia  +ak+          r++gl+p ++i+C+n
   EEA21000.1  92 VGP----------NILKFIAPVIAKGI-------DAREEGLPPIAVIACEN 125
                  ***..........*************4.......6678899*********9 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 1
                  HHHTTTT-EEEEE-SSS---EEEE--EEEEEEGGG-HHHHHHHH CS
  Mannitol_dh  45 aLkaqdelyvviekgeeskearlvgsvnavlsveedlealieam 88 
                  aL +  +l +   + +e+++++              ++++i  +
   EEA21000.1 253 ALDETASLIISKHEITEQEQKEY-------------VKTIISRI 283
                  22222222222222223333333.............33333333 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   2.7e-05     0.054       5      86 ..       8      92 ..       5      97 .. 0.72
   2 ?   -1.1   0.1      0.74   1.5e+03      29      67 ..     240     279 ..     221     292 .. 0.62

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 2.7e-05
                E--SCCHHHHHHHHHHT.T-EEEEE-S-HHHHHHHHHHHHHHHHCCTTTTSS-HH..HHCCCHHCEEEES-HHHHHC-SEEEE-S CS
     3HCDH_N  5 iGaGtmGagiaavfasa.gleVvlvdiseealekalekieksleklvekgklkee..eveaalarisfttdleeavdadlviEav 86
                 G G +G+g  a f+++ g+eVv +d+ ++ +e+ +++ + ++ +  e+g+ ++   + +a+ ++ +  + ++e++ ad+v  av
  EEA21000.1  8 FGGGNIGRGFVAEFLHEsGYEVVFIDVVPQVIESLNKNKSYEVTEISEEGEKTKTitNYRALSSKTQEPEVVKEIATADVVTCAV 92
                599******766666555****************999999999999998887633003333334444444556666777776665 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.74
                 -S-HHHHHHH.HHHHHHHHHCCTTTTSS-HHHHCCCHHCE CS
     3HCDH_N  29 diseealeka.lekieksleklvekgklkeeeveaalari 67 
                  ++ee+++ka ++++ ++ +  ++k++++e+e ++++++i
  EEA21000.1 240 AMAEETIHKAvHAALDETASLIISKHEITEQEQKEYVKTI 279
                 3444444444144455566666788888877777777665 PP

>> UDPG_MGDP_dh_N  UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.2   1.6e-05     0.032       6      85 ..       8      93 ..       3      98 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.6e-05
                    E--STTHH.HHHHHHHHCTSEEEEE-S-HHHHHHHCTTS-S....S--TTHH.HHHHHHCHTTTEEEES-HHHHHHC-SEEEE--- CS
  UDPG_MGDP_dh_N  6 iGlGYvGl.vtaavlaeighevigvDideekvdklnsgkip....iyepgLe.elvkkavesgrlsfttdvekaveeadvifiaVg 85
                    +G G +G    a  l e g ev+++D+  + +++ln++k++    i e+g + + +++ ++ +  + + +v k+++ adv+  aVg
      EEA21000.1  8 FGGGNIGRgFVAEFLHESGYEVVFIDVVPQVIESLNKNKSYevteISEEGEKtKTITNYRALSSKTQEPEVVKEIATADVVTCAVG 93
                    788889852567789999*******************98643222666665413444444444455556788899999**999998 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.1     0.001         2       5      44 ..       9      50 ..       6     109 .. 0.87
   2 ?    4.7   0.2     0.018        36      47     109 ..     229     296 ..     213     299 .. 0.64

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.001
                S-SHHHHH.HHHHHHH.TTEEEEEEESSHHHHHHHHHTT.SEE CS
      TrkA_N  5 GlGrvGrs.laeeLse.ggkdvvvidkdeerveelreeg.lev 44
                G G++Gr  +ae L+e g+ +vv id  ++++e+l +++ +ev
  EEA21000.1  9 GGGNIGRGfVAEFLHEsGY-EVVFIDVVPQVIESLNKNKsYEV 50
                99*****934555666555.5*************987765554 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.018
                 S-TTSHHHHHHTTGGGE..SEEEE-SSSHHHHHHHHHHHHHHTSS...SEEEEEESSGGGHHHHHHHT CS
      TrkA_N  47 gdatdeevLeeagieka..daviaatgddeanilavllakelnpk...kkiiaraqdpehaellkklg 109
                 g  + +++++ea +e+   +av aa+++ ++ i+  + + e  +k   k+ii+r+++p  +++++++g
  EEA21000.1 229 GYKAGKKTIHEAMAEETihKAVHAALDETASLIISKHEITEQEQKeyvKTIISRISNPYLEDVVERVG 296
                 44444444555544443113466777555555555555555444467899**************9987 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.2   9.2e-05      0.18     148     236 ..       8      93 ..       1     115 [. 0.74

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 9.2e-05
                  ES-SHHHHHHHHH.HHHHT-EEEEEESSSSSSTTS-HHHHHHHHHHHHHTTEEEEESCEEEEEEETTEEEEEEETTSCE.EEESEEEE-S- CS
                  xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxx RF
  Pyr_redox_2 148 vGgGyiGvElAaa.laklgkevtlveardrllraldkelsaaleealekeGvevklgtsvkeidgngeklevvledgee.idadlvvvavG 236
                   GgG+iG  + a+ l++ g+ev+ ++  +++ ++l+k+ s +++e  e+ G ++k+ t+  ++ ++++    + e  +e   ad v  avG
   EEA21000.1   8 FGGGNIGRGFVAEfLHESGYEVVFIDVVPQVIESLNKNKSYEVTEISEE-GEKTKTITNYRALSSKTQ----EPEVVKEiATADVVTCAVG 93 
                  6******99766548***************************9998888.667777677766665555....3333333133555555666 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00016      0.33      32     107 ..      14      84 ..       9      86 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00016
  Methyltransf_23  32 GtGillevlrengfsvtgvDlspeaveiaekakkaqkdqfdeqeaaepqgkfdlIvlrevlehvpdppellrqiat 107
                      G G ++e l e g++v+++D  p+ +e +     ++++++   e++e+ +k+++I++   l +    pe+++ iat
       EEA21000.1  14 GRGFVAEFLHESGYEVVFIDVVPQVIESL-----NKNKSYEVTEISEEGEKTKTITNYRALSSKTQEPEVVKEIAT 84 
                      667788999****************9964.....66777777899******************9999999999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (737 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       655  (0.036533); expected 358.6 (0.02)
Passed bias filter:                      523  (0.0291706); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.73u 0.29s 00:00:01.02 Elapsed: 00:00:00.47
# Mc/sec: 4735.64
//
Query:       EEA21001.1  [L=259]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.2e-27   95.5   9.0    3.8e-27   95.3   9.0    1.0  1  SUR7             SUR7/PalI family
  ------ inclusion threshold ------
        4.7    7.1  13.8       0.21   11.5   6.0    2.0  2  Fig1             Ca2+ regulator and membrane fusion protein F


Domain annotation for each model (and alignments):
>> SUR7  SUR7/PalI family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.3   9.0   4.2e-31   3.8e-27       4     212 .]       8     238 ..       5     238 .. 0.89

  Alignments for each domain:
  == domain 1  score: 95.3 bits;  conditional E-value: 4.2e-31
        SUR7   4 illflslaalilllfailgsiknstpltsiylskfdls.gldlaqi...........gladvysfgvwgyC.......dnsdvnytkCskpkagypfdp 83 
                 i+ ++ l+++il++++++++  ++++l++  ++ +d+s + + + i           gl+d+y ++v +yC       ++   n t+Csk ka + f+p
  EEA21001.1   8 ISKVFALVSFILSMLCLFAGS-QNSVLQNASVMMLDTSaSQPTSAIqsavnsttadlGLKDFYAIHVLSYCegtfkraGEGGLNLTSCSKRKAPFAFNP 105
                 6779*****************.77778888888888885555555599******************************99******************9 PP

        SUR7  84 ...l.eelnsesngkvd..lPsnlrktlsklnnltkalfilhiialvlsfislvvgllaicvspdnsrllsflnlllsvlsflatllaalldtllfvfv 176
                    + +e++ + n   d  +P++++++   +    ka+ +l++++++++ +++++ +l        ++  +f  l++ vlsf+++ +++ l+t++ v +
  EEA21001.1 106 tkvFsTEFKAGFNIS-DinWPDRINDDFEVMEMTAKAMSVLYVVGVAATGVAFLMEILLTQ--AGGKP-SMFAHLFFVVLSFVCLGISSSLATVIAVQF 200
                 653266666666533.267************************************777764..35666.899*************************** PP

        SUR7 177 rkkin..lkefgikaslglkflafaWlalaaallvvif 212
                  + in   +e+g  a+ g +fl+++W+a+++++l+ +f
  EEA21001.1 201 VNLINrhGQEYGLVAKGGGSFLGMTWSAVMLSFLTIVF 238
                 *********************************99876 PP

>> Fig1  Ca2+ regulator and membrane fusion protein Fig1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.9     0.057   5.1e+02     115     150 ..       8      43 ..       1      62 [. 0.62
   2 ?   11.5   6.0   2.3e-05      0.21      79     185 ..     143     242 ..     117     245 .. 0.79

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.057
        Fig1 115 vskvalvlsflllllwlvgalwqhvassaastlvee 150
                 +skv  ++sf+l++l l++     v  +a+++++  
  EEA21001.1   8 ISKVFALVSFILSMLCLFAGSQNSVLQNASVMMLDT 43 
                 566666666666666666655555555565555544 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 2.3e-05
        Fig1  79 pyllmvaiiLtlllfllllyfplgseipllPfkskavskvalvlsflllllwlvgalwqhvassaastlveeasmgi.vkskvGkkaealgWfafafll 176
                 + l +v ++ t + fl+ +  +         +k      + l +++l+++ +++++ + +v ++ +++l+++  ++  + +k G++  +++W a+++ +
  EEA21001.1 143 SVLYVVGVAATGVAFLMEILLT------QAGGKPS--MFAHLFFVVLSFVCLGISSSLATVIAVQFVNLINRHGQEYgLVAKGGGSFLGMTWSAVMLSF 233
                 4566777777777777776654......2333333..57789999999999***999999999999999998888777889999************999 PP

        Fig1 177 lvclglwvl 185
                 l+ +  +++
  EEA21001.1 234 LTIVFSVIT 242
                 988877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (259 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       969  (0.0540465); expected 358.6 (0.02)
Passed bias filter:                      468  (0.026103); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.49
# Mc/sec: 1579.92
//
Query:       EEA21002.1  [L=850]
Description: COPI vesicle coat beta' subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.4e-171  571.5   0.0   6.6e-171  569.2   0.0    1.9  2  Coatomer_WDAD  Coatomer WD associated region
    9.1e-38  127.6   7.3      1e-05   26.2   0.0    7.9  7  WD40           WD domain, G-beta repeat
    1.1e-08   35.2   0.4        3.4    8.0   0.1    6.2  6  ANAPC4_WD40    Anaphase-promoting complex subunit 4 WD40 doma
    1.5e-05   23.9   3.2        0.2   10.3   0.1    4.2  4  Nup160         Nucleoporin Nup120/160
  ------ inclusion threshold ------
      0.011   15.8   0.0        5.4    7.1   0.0    3.6  3  BBS2_Mid       Ciliary BBSome complex subunit 2, middle regio
      0.055   13.7   0.1       0.22   11.7   0.0    2.0  2  MetallophosC   C terminal of Calcineurin-like phosphoesterase


Domain annotation for each model (and alignments):
>> Coatomer_WDAD  Coatomer WD associated region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.1      0.15   4.6e+02      33     150 ..      98     231 ..      74     281 .. 0.59
   2 !  569.2   0.0  2.2e-174  6.6e-171       1     445 []     318     761 ..     318     761 .. 0.99

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.15
                    XXXXXXXXXXXXXXXXX.XXXXXXXXXX.XXXXXXXXXXXXXXXXXXX.......XXXXXXXXXXXXXXX.XXX.XXXX..XXXXXXXXXXXXXXX CS
  Coatomer_WDAD  33 iypqslshnpngrfvlV.cgdgeyiiyt.alalrnkaygkgldfvwvs.......snrfavlessksvkifknf.kekk..tksikleyqvdkifg 116
                     y++s+  +p++ fvl   +d ++++    ++++  +  +g++   +         n fa     ++vki  n+ +++   t + + ++ v+++ +
     EEA21002.1  98 DYIRSIVVHPTQPFVLTaSDDMTIKLWDwDKGWKCVQVFEGHSHYVMGlainpkdTNTFASACLDRTVKI-WNLgSGHAnyTLEAHETKGVNSVDY 192
                    4566667777777776633333344433644444444444433322222333334566777777778888.5552333300222333334444444 PP

                    ......XXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXX CS
  Coatomer_WDAD 117 ......GalLgvksegsvsfYDweqgklvrridvkkvknV 150
                           +lL ++++++v ++D +++ l++ ++ +  +nV
     EEA21002.1 193 ygqadkPYLLTTSDDKTVKVWDYTTKALIATLEGHT-SNV 231
                    767666778888888888888888888888887665.555 PP

  == domain 2  score: 569.2 bits;  conditional E-value: 2.2e-174
                    XXXXXXXXXXXX....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXXX CS
  Coatomer_WDAD   1 esevrqanikkkeelkdgellslqlkelgsieiypqslshnpngrfvlVcgdgeyiiytalalrnkaygkgldfvwvs...snrfavlessksvki 93 
                    ++ev +++i++  +lkdg +l l++k+lgs+eiypq+l h+pngrfv Vcgdgeyiiytala+rnka+g++ldf+w+s   sn++a++es++svki
     EEA21002.1 318 HTEVVSTVIRGD-DLKDGAPLALPTKDLGSCEIYPQTLVHSPNGRFVSVCGDGEYIIYTALAWRNKAFGQALDFAWGSrdnSNDYAIRESATSVKI 412
                    578999999999.8****************************************************************999999************ PP

                    .XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.............. CS
  Coatomer_WDAD  94 fknfkekktksikleyqvdkifgGalLgvksegsvsfYDweqgklvrridvkkvknVvwsddgelvalvskdtvyilsynleavee.....edeee 184
                    fknfke+k + +++ +q++ + gG lLgvk +g++ ++Dwe+g+lvrri+v++ ++V+ws++gelval+++dt yil++++e++ +     e +e+
     EEA21002.1 413 FKNFKEQK-EGLDVGFQAEGLSGGVLLGVKGQGGIGLFDWETGSLVRRIEVEP-REVYWSESGELVALACEDTCYILRFSRENYVNglnagEADED 506
                    ********.9*******************************************.*******************************9********** PP

                    ....XXXXXXX.XXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Coatomer_WDAD 185 gvedafevlhelsesiksgaWvgdvfiYttsnnrlkylvngevgiikhldktlyilgykgkenklylldkdgnvvsleidlselefktavlrkdle 280
                    gve+afev++++se++++g Wvgd+fiYt+s+nrl+ylv++++++i+h+d+ +yilgy+++++++yl+dkd+++vs+ ++ls++e++t+vlr+d++
     EEA21002.1 507 GVESAFEVVTDISETVRTGEWVGDCFIYTNSTNRLNYLVGDQTYTISHFDQAMYILGYLPRDGRIYLADKDVEIVSFALSLSVVEYQTLVLRGDMD 602
                    ************************************************************************************************ PP

                    XXXXXXXXXXXX.......XXXXXXXXXXXXXXXX-GGGSS-HHHHHHHHHHTT-HHHHHHHHHHH--HHHHHHHHHHHHHTT-HHHHHHHHHHTT CS
  Coatomer_WDAD 281 evlkiiaasnllpeipkeegqkiirfLekkgypelAlqlvqDpetkFdLAlelgnLelAlelakelddeekWkkLgdaAlsqgniklaeeayqkak 376
                    +      a++ll++ip+++ +ki+rfLe +g++elAl+++ D+e++FdLAl+l +L++Alela+e+d e+kWk++gdaAl+ ++++la+e++++ak
     EEA21002.1 603 S------AAELLADIPQDQMNKIARFLEGQGFKELALEVSPDSEHRFDLALSLSRLDIALELAREADVEHKWKTVGDAALAAWDLNLAQECFTHAK 692
                    9......699************************************************************************************** PP

                    -HHHHHHHHHHHT-HHHHHHHHHHHHHTT-HHHHHHHHHHHT-HHHHHHHHHHTT-HHHHHHHHHHTT. CS
  Coatomer_WDAD 377 dfdkLllLylstgnkekLkkLakiaekkgdyniafqaalllgdvekcvdlLiksgrlpeAalfAktygl 445
                    d+ +LllLy+s+ n+++L++La++a+ +g +n+af+a + +gd+++c+dlL++++rl+eA+lfA+ty++
     EEA21002.1 693 DLGSLLLLYTSSRNTDGLRSLADQASVAGLHNVAFSALWTIGDIDACIDLLVSTNRLAEAVLFAQTYKP 761
                    *******************************************************************86 PP

>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.3   0.0   0.00036       1.1      13      38 .]      16      41 ..       9      41 .. 0.90
   2 !    9.9   0.0   0.00049       1.5      22      38 .]      67      83 ..      49      83 .. 0.89
   3 !   26.2   0.0   3.4e-09     1e-05       3      38 .]      89     125 ..      87     125 .. 0.93
   4 !   25.6   0.1   5.3e-09   1.6e-05       1      38 []     130     169 ..     130     169 .. 0.91
   5 !   24.0   0.0   1.7e-08   5.1e-05       5      38 .]     177     214 ..     173     214 .. 0.92
   6 !   25.3   0.0   6.4e-09   1.9e-05       3      37 ..     220     255 ..     218     256 .. 0.91
   7 ?    2.5   0.0       0.1   3.1e+02      16      32 ..     354     369 ..     342     373 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00036
                EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40 13 vtslafspdgawlasGsdDgtvriWd 38
                v +++f+p  +w+++  + g+v+iW+
  EEA21002.1 16 VKGIDFHPTEPWILTTLYSGHVYIWS 41
                7899**********9977*******5 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.00049
                SSEEEEEETTSEEEEEE CS
        WD40 22 gawlasGsdDgtvriWd 38
                ++w+++GsdD  vr+++
  EEA21002.1 67 KNWIVCGSDDFQVRVYN 83
                79*************97 PP

  == domain 3  score: 26.2 bits;  conditional E-value: 3.4e-09
                 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +++++++H + ++s+ ++p +++++++sdD t+++Wd
  EEA21002.1  89 KITSFEAHpDYIRSIVVHPTQPFVLTASDDMTIKLWD 125
                 6789****777*************************9 PP

  == domain 4  score: 25.6 bits;  conditional E-value: 5.3e-09
                 TEEEEEEESSSS.EEEEE.EETTSSEEEEEETTSEEEEEE CS
        WD40   1 gqclrtltGHss.vtsla.fspdgawlasGsdDgtvriWd 38 
                 ++c+++++GHs+ v +la +++d + +as++ D+tv+iW+
  EEA21002.1 130 WKCVQVFEGHSHyVMGLAiNPKDTNTFASACLDRTVKIWN 169
                 79********778*****88888888999999*******8 PP

  == domain 5  score: 24.0 bits;  conditional E-value: 1.7e-08
                 EEEESS..SSEEEEE..EETTSSEEEEEETTSEEEEEE CS
        WD40   5 rtltGH..ssvtsla..fspdgawlasGsdDgtvriWd 38 
                 +tl++H  ++v+s++   + d+++l++ sdD+tv++Wd
  EEA21002.1 177 YTLEAHetKGVNSVDyyGQADKPYLLTTSDDKTVKVWD 214
                 6899**9888****************99*********9 PP

  == domain 6  score: 25.3 bits;  conditional E-value: 6.4e-09
                 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 
                 ++ tl+GH s+v+  +++p+ + ++sGs+Dgtv++W
  EEA21002.1 220 LIATLEGHtSNVSFACYHPELPVIISGSEDGTVKVW 255
                 5789****888*8888******************** PP

  == domain 7  score: 2.5 bits;  conditional E-value: 0.1
                 EEEETTSSEEEEEETTS CS
        WD40  16 lafspdgawlasGsdDg 32 
                 l  sp+g++++ ++ Dg
  EEA21002.1 354 LVHSPNGRFVSVCG-DG 369
                 5589******9999.87 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.6   0.0    0.0067        20      37      80 ..      12      55 ..       2      69 .. 0.90
   2 ?    1.6   0.0      0.12   3.5e+02      41      84 ..      58     100 ..      50     108 .. 0.80
   3 !    8.0   0.1    0.0011       3.4      19      89 ..     119     192 ..     107     195 .. 0.80
   4 !    6.4   0.0    0.0037        11      30      90 ..     213     279 ..     203     281 .. 0.81
   5 ?    0.9   0.0      0.18   5.5e+02      49      81 ..     433     465 ..     408     468 .. 0.81
   6 ?    4.0   0.0      0.02        61      42      75 ..     465     497 ..     460     510 .. 0.72

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0067
  ANAPC4_WD40 37 edsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvks 80
                 ++++v+++ ++p +  +      g+v + + e++ ++++++ ++
   EEA21002.1 12 RSERVKGIDFHPTEPWILTTLYSGHVYIWSYETQSIIKTFELTD 55
                 5789**********************************998765 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.12
  ANAPC4_WD40  41 vrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekav 84 
                  vr+ ++    + ++ + +d +vr+++ ++ + + s++++ +  +
   EEA21002.1  58 VRAGRFIARKNWIVCGSDDFQVRVYNYNTSEKITSFEAHPDY-I 100
                  55555666677889999999****************999884.5 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.0011
  ANAPC4_WD40  19 llvfRlngqrvwtl..eedkedsevrsLaWkpdg.klLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                  + ++  ++ + w+     +++++ v +La +p++ + +a a+ d +v++ +  sg+   +l+++++k v+++++
   EEA21002.1 119 MTIKLWDWDKGWKCvqVFEGHSHYVMGLAINPKDtNTFASACLDRTVKIWNLGSGHANYTLEAHETKGVNSVDY 192
                  55555677777777554467888999***99866379****************************999988876 PP

  == domain 4  score: 6.4 bits;  conditional E-value: 0.0037
  ANAPC4_WD40  30 wtl.......eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgWg 90 
                  w+        + +++ s+v+  +++p+  ++  + +dg+v++ +a++ ++ +sl+++ e +  c++++
   EEA21002.1 213 WDYttkaliaTLEGHTSNVSFACYHPELPVIISGSEDGTVKVWHASTYRLEQSLNYGLE-RAWCVSYQ 279
                  4444444554567889999999*************************999999998877.47777765 PP

  == domain 5  score: 0.9 bits;  conditional E-value: 0.18
  ANAPC4_WD40  49 dgklLavaysdgevrlldaesgkvvhslsvkse 81 
                  +g +L  +  +g + l+d e+g +v+ ++v+  
   EEA21002.1 433 SGGVLLGVKGQGGIGLFDWETGSLVRRIEVEPR 465
                  577888888999**************9999876 PP

  == domain 6  score: 4.0 bits;  conditional E-value: 0.02
  ANAPC4_WD40  42 rsLaWkpdgklLavaysdgevrlldaesgkvvhs 75 
                  r++ W+++g+l a a++d+ + +l  + ++ v+ 
   EEA21002.1 465 REVYWSESGELVALACEDT-CYILRFSRENYVNG 497
                  5788999999999999885.55555555555555 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.0     0.022        66     220     249 ..      98     128 ..      83     137 .. 0.75
   2 !    8.1   0.0   0.00029      0.87     229     266 ..     152     187 ..     140     199 .. 0.77
   3 !   10.3   0.1   6.7e-05       0.2     229     256 ..     197     224 ..     189     252 .. 0.87
   4 ?   -0.9   0.0      0.16   4.7e+02     218     251 ..     228     261 ..     223     267 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.022
                 EEET......TTTEEEEEETT-EEEEEETTT CS
      Nup160 220 dvavavvei.gqtylfalsrdgkLrvWnllt 249
                 d + ++v   +q +++++s d ++++W+ + 
  EEA21002.1  98 DYIRSIVVHpTQPFVLTASDDMTIKLWDWDK 128
                 55555554469*****************875 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.00029
                 TTTEEEEEETT-EEEEEETTTTEEEEEEE--.-SSSTT CS
      Nup160 229 gqtylfalsrdgkLrvWnlltgkclatidllrdeeaqd 266
                 + ++ +++++d+++++Wnl +g   +t +    e++ +
  EEA21002.1 152 DTNTFASACLDRTVKIWNLGSGHANYTLEAH--ETKGV 187
                 789999*************999988887766..44444 PP

  == domain 3  score: 10.3 bits;  conditional E-value: 6.7e-05
                 TTTEEEEEETT-EEEEEETTTTEEEEEE CS
      Nup160 229 gqtylfalsrdgkLrvWnlltgkclati 256
                 ++ yl++ s d++++vW+++t+ ++at 
  EEA21002.1 197 DKPYLLTTSDDKTVKVWDYTTKALIATL 224
                 7889********************9995 PP

  == domain 4  score: -0.9 bits;  conditional E-value: 0.16
                 EEEEET.....TTTEEEEEETT-EEEEEETTTTE CS
      Nup160 218 sldvavavveigqtylfalsrdgkLrvWnlltgk 251
                 +++v++a+ + +  ++ + s dg+++vW  +t++
  EEA21002.1 228 TSNVSFACYHPELPVIISGSEDGTVKVWHASTYR 261
                 67788888888888999999********999986 PP

>> BBS2_Mid  Ciliary BBSome complex subunit 2, middle region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.0    0.0018       5.4      12      31 ..      67      86 ..      60     125 .. 0.81
   2 ?   -1.2   0.0      0.71   2.1e+03      16      31 ..     113     128 ..     102     192 .. 0.58
   3 ?    4.1   0.0     0.015        45      11      69 ..     197     259 ..     187     296 .. 0.79

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0018
    BBS2_Mid 12 eneLvvgsddfeirvfkeee 31
                +n +v gsddf++rv++ ++
  EEA21002.1 67 KNWIVCGSDDFQVRVYNYNT 86
                6889***********98764 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.71
    BBS2_Mid  16 vvgsddfeirvfkeee 31 
                 + +sdd++i++++ ++
  EEA21002.1 113 LTASDDMTIKLWDWDK 128
                 5677777777766553 PP

  == domain 3  score: 4.1 bits;  conditional E-value: 0.015
    BBS2_Mid  11 geneLvvgsddfeirvfk..eeelvaeitetekvvslarleker..fayaleNGtvgvyekke 69 
                 ++ +L+  sdd +++v++   + l+a+++ +   vs+a  ++e   ++ + e Gtv+v++ ++
  EEA21002.1 197 DKPYLLTTSDDKTVKVWDytTKALIATLEGHTSNVSFACYHPELpvIISGSEDGTVKVWHAST 259
                 56799999***9999965115678888888888888888888876688899999999998765 PP

>> MetallophosC  C terminal of Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   7.4e-05      0.22      47      94 ..      74     142 ..      71     168 .. 0.82
   2 ?   -2.1   0.0       1.4   4.1e+03      66      87 ..     193     223 ..     163     236 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 7.4e-05
  MetallophosC  47 dedyqmrlyapgevkkgakk......................akknsvvvnvwngdpgwk.Vevyedgkal 94 
                   ++d+q+r+y+ ++ +k   +                      + +++++++ w++d+gwk V+v+e+ + +
    EEA21002.1  74 SDDFQVRVYNYNTSEKI--TsfeahpdyirsivvhptqpfvlTASDDMTIKLWDWDKGWKcVQVFEGHSHY 142
                   6899*****88877643..1458999****************99****************88888875554 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.4
  MetallophosC  66 k.........akknsvvvnvwngdpgwkVev 87 
                   +         +++++ +v+vw+++++  +  
    EEA21002.1 193 YgqadkpyllTTSDDKTVKVWDYTTKALIAT 223
                   2344445555566677788888877766555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (850 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       472  (0.0263261); expected 358.6 (0.02)
Passed bias filter:                      448  (0.0249875); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.77u 0.27s 00:00:01.04 Elapsed: 00:00:00.45
# Mc/sec: 5654.18
//
Query:       EEA21003.1  [L=241]
Description: NADH-ubiquinone oxidoreductase 299 kDa subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.1e-29  100.2   1.7    3.2e-26   90.9   0.0    2.3  2  ETC_C1_NDUFA5  ETC complex I subunit conserved region
     0.0064   16.6   0.0      0.015   15.4   0.0    1.6  1  Ku_PK_bind     Ku C terminal domain like


Domain annotation for each model (and alignments):
>> ETC_C1_NDUFA5  ETC complex I subunit conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.9   0.0   3.6e-30   3.2e-26       1      65 [.      27      97 ..      27      99 .. 0.97
   2 !    8.3   0.6   0.00023         2      49      67 .]     177     195 ..     166     195 .. 0.91

  Alignments for each domain:
  == domain 1  score: 90.9 bits;  conditional E-value: 3.6e-30
  ETC_C1_NDUFA5  1 GLavhpnPreaLialytktLkkLkkiPessvYRqsvEaltkhRlkiVee......eedvekiekkigagqi 65
                   GL +hp+Pr++Li lyt+tL+kLk++Pess+YRqsvEalt+hRl+iVe+      +e+ ++++k + ++++
     EEA21003.1 27 GLVTHPSPRPTLIFLYTQTLEKLKQFPESSAYRQSVEALTRHRLQIVESakppgfDEWLQRVKKVVAENPE 97
                   99**********************************************999*************9999875 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.00023
  ETC_C1_NDUFA5  49 eeedvekiekkigagqiee 67 
                    e+e++++ie+kigag iee
     EEA21003.1 177 EAEQIAEIENKIGAGLIEE 195
                    4899*************98 PP

>> Ku_PK_bind  Ku C terminal domain like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   1.7e-06     0.015      33     103 ..      48     115 ..      41     125 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 1.7e-06
  Ku_PK_bind  33 lvedslgdssydkaveclkalReeaieeeepelyNdFlrdlkkklqseggdrrefWkelvkkeklglIskd 103
                  +++  ++s y++ ve+l+  R + +e  +p  ++++l+ +kk +    ++ + f k+ + ++++  I++d
  EEA21003.1  48 KLKQFPESSAYRQSVEALTRHRLQIVESAKPPGFDEWLQRVKKVVA---ENPERFAKARLANGTFAGIQQD 115
                 567777899************************************8...4667788778877777777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (241 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       457  (0.0254894); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.41u 0.24s 00:00:00.64 Elapsed: 00:00:00.38
# Mc/sec: 1914.13
//
Query:       EEA21004.1  [L=743]
Description: disulfide isomerase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.3e-43  147.2   0.0    2.7e-24   85.1   0.0    4.5  4  Thioredoxin     Thioredoxin
    8.4e-14   51.9   0.0    0.00013   21.9   0.0    4.5  5  Thioredoxin_6   Thioredoxin-like domain
    6.2e-05   23.4   1.1        1.2    9.6   0.3    3.9  3  Thioredoxin_2   Thioredoxin-like domain
    0.00076   19.8   0.1        3.2    8.1   0.0    4.2  4  Thioredoxin_8   Thioredoxin-like
     0.0017   18.3   0.0       0.24   11.4   0.0    3.0  3  HyaE            Hydrogenase-1 expression protein HyaE
  ------ inclusion threshold ------
      0.044   14.0   1.5       0.25   11.6   0.1    2.8  3  Thioredoxin_7   Thioredoxin-like
       0.14   11.2   1.1       0.27   10.2   0.3    1.8  2  Calsequestrin   Calsequestrin
       0.15   12.2   0.1        6.1    7.0   0.0    2.6  2  Thioredoxin_3   Thioredoxin domain
       0.83   10.0   4.7       0.13   12.6   0.7    1.7  2  Fungus-induced  Fungus-induced protein
        3.1    7.5   8.1         14    5.5   0.0    3.6  4  TraF            F plasmid transfer operon protein


Domain annotation for each model (and alignments):
>> Thioredoxin  Thioredoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.0   1.7e-08     3e-05       5      47 ..      53      93 ..      50     102 .. 0.90
   2 !   29.5   0.0   3.2e-10   5.7e-07      48     102 ..     117     173 ..     104     174 .. 0.90
   3 !   85.1   0.0   1.5e-27   2.7e-24       3     101 ..     270     367 ..     268     369 .. 0.92
   4 ?    2.5   0.0     0.078   1.4e+02      59      83 ..     428     452 ..     410     463 .. 0.82

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 1.7e-08
                 SSHHHHHHHHTTTSSEEEEEEE-TTSHHHHCHHHHHHHHHHHC CS
  Thioredoxin  5 ltkenFeeevakekklvlveFyApwCghCkalaPeleklaeel 47
                 l  +nF++++a+    ++v+ ++p C+hC+a+aP +++l e +
   EEA21004.1 53 LGPDNFKTTIAN--GYWFVKHFSPSCPHCQAIAPSWQTLYEFY 93
                 5679*******9..***********************998755 PP

  == domain 2  score: 29.5 bits;  conditional E-value: 3.2e-10
                  TT..TSEEEEEETTTSHHHHHHTT-SSSSEEEEEETTEEEEEEESS-HHHHHHHHHH CS
  Thioredoxin  48 kd..kvklakvdvdenedlakkyevegiPtlklfkngkevkkyegarekeklaaflk 102
                  ++  ++ +a++++ + +dl+ +++++ +Pt+ l++ng+ v++y+g ++ + l +f++
   EEA21004.1 117 TGyyDFHFAEMNCLAFRDLCVELDIKFFPTFSLYHNGELVEQYSGMKNMQGLSNFIE 173
                  4455899***********************************************997 PP

  == domain 3  score: 85.1 bits;  conditional E-value: 1.5e-27
                  EESSHHHHHHHHTTTSSEEEEEEE-TTSHHHHCHHHHHHHHHHHCTTTSEEEEEETTTSHHHHHHTT-SSSSEEEEEETTEEEEEEESS-HHHHHHHH CS
  Thioredoxin   3 lvltkenFeeevakekklvlveFyApwCghCkalaPeleklaeelkdkvklakvdvdenedlakkyevegiPtlklfkngkevkkyegarekeklaaf 100
                  + lt+e+F++ v  ++++++v+FyApwC hC+alaP + ++a+e+k+++ + +v++d ++ l+k+ +v+g+Pt+ +fk g+   +y+g r   +l+++
   EEA21004.1 270 VPLTAESFQKFVTRTRDPWFVKFYAPWCHHCQALAPPWLTMAKEMKGQLNVGEVNCDVEKRLCKDAGVKGYPTMFFFKGGE-KVEYQGLRGVGDLISY 366
                  57899*********************************************************************9999999.5678998888888776 PP

                  H CS
  Thioredoxin 101 l 101
                   
   EEA21004.1 367 A 367
                  6 PP

  == domain 4  score: 2.5 bits;  conditional E-value: 0.078
                  TTSHHHHHHTT-SSSSEEEEEETTE CS
  Thioredoxin  59 denedlakkyevegiPtlklfkngk 83 
                  +++e la++++++  P l+++++g+
   EEA21004.1 428 TDSEILADRFKISTWPRLLVVRDGR 452
                  5567899****************98 PP

>> Thioredoxin_6  Thioredoxin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.7   0.0    0.0034         6      32      75 ..     134     176 ..     110     181 .. 0.77
   2 ?   -3.1   0.1       3.4   6.1e+03      45      80 ..     261     290 ..     221     292 .. 0.59
   3 !    8.9   0.0   0.00073       1.3      15     121 ..     310     416 ..     307     421 .. 0.77
   4 !   21.9   0.0   7.3e-08   0.00013       8     122 ..     408     524 ..     405     534 .. 0.75
   5 !    9.7   0.0   0.00041      0.74     113     163 ..     564     615 ..     550     625 .. 0.76

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0034
                    HHHHHTT--S.SEEEEEETTTTEEEEEETHT--HHHHHHHHHHH- CS
  Thioredoxin_6  32 evadklgvke.pavllfrkfdeekvkydgekitvddlkkfiekns 75 
                    +++ +l++k+ p+  l+++  e  ++y+g k + + l++fie++ 
     EEA21004.1 134 DLCVELDIKFfPTFSLYHN-GELVEQYSGMK-NMQGLSNFIEEKL 176
                    46677999*99********.677799***85.**********986 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 3.4
                    EEEETTTTEEEEEETHT--HHHHHHHHHHH---SEE CS
  Thioredoxin_6  45 llfrkfdeekvkydgekitvddlkkfieknslplvr 80 
                    ++++++ ++   ++   +t+++ +kf++  + p++ 
     EEA21004.1 261 IIYNPQGTS---VP---LTAESFQKFVTRTRDPWFV 290
                    334443332...22...3566666666666666665 PP

  == domain 3  score: 8.9 bits;  conditional E-value: 0.00073
                    HTTT-T.TSEEEEE-...-HHHHHHTT--S.SEEEEEETTTTEEEEEETHT--HHHHHHHHHHH---S..EEE-SHHHHHHHHTSS--EEEEEEE- CS
  Thioredoxin_6  15 vakelkgdvrfgvtk...skevadklgvke.pavllfrkfdeekvkydgekitvddlkkfieknslpl..vreltpenaeelfeeglppllllflk 104
                    +ake+kg + +g ++   +k ++++ gvk+ p+  +f++   ekv+y+g    v dl +  +k+      v  ++  +++e  e+g  +++l+f++
     EEA21004.1 310 MAKEMKGQLNVGEVNcdvEKRLCKDAGVKGyPTMFFFKG-G-EKVEYQGL-RGVGDLISYAQKAVDTGagVKYVDASTFKEMEETG-EVIFLYFFD 401
                    5777777777777753225669999*****999999999.4.459****9.79**********998765688999******88888.667777775 PP

                    TTSTTHHHHHHHHHHHH CS
  Thioredoxin_6 105 kddeeteklkkaiekva 121
                    k    t++  +a+e++a
     EEA21004.1 402 K--ATTSEDFAALEQLA 416
                    5..44666666666665 PP

  == domain 4  score: 21.9 bits;  conditional E-value: 7.3e-08
                    HHHHHHHHTTT-T.TSEEEEE--HHHHHHTT--S.SEEEEEET....TTTEEEEEETH.....T--HHHHHHHHHHH---SEEE-SHHHHHHHHTS CS
  Thioredoxin_6   8 eseiFekvakelkgdvrfgvtkskevadklgvke.pavllfrk....fdeekvkydge.....kitvddlkkfieknslplvreltpenaeelfee 93 
                    ++ ++e+ a  l g+ r + t s+ +ad +++++ p +l++r+        +     +     + +   + ++++ + lp v+elt  na+e++++
     EEA21004.1 408 DFAALEQLALPLVGHARLVKTDSEILADRFKISTwPRLLVVRDgrptY--FN-----AlapydMRDNPRVLEWMRGHWLPIVPELTVSNAKEIMQN 496
                    56677777777788888888999999999*************833221..22.....22344467******************************* PP

                    S--EEEEEEE-TTSTTHHHHHHHHHHHHH CS
  Thioredoxin_6  94 glppllllflkkddeeteklkkaiekvak 122
                    +  +l +l + k+++e +  +++++++a 
     EEA21004.1 497 KYVVLGILSH-KRSDEFRLGQAELKNAAM 524
                    *665544444.556676666666666665 PP

  == domain 5  score: 9.7 bits;  conditional E-value: 0.00041
                    HHHHHHHHHHHTTTT-EEEEEETTGGHHHHH.HTT--GGG-SEEEEEESSSS CS
  Thioredoxin_6 113 lkkaiekvakefkdkinfaladaksfkrple.ylglsssdlPvivivdsash 163
                    +k+   ++ +e k+++ fa++d++ + r l+  +g++  d+  ++i d ++ 
     EEA21004.1 564 AKSMHINIREEDKKQVAFAWVDGDFWDRWLRtTYGIDVKDGERVIINDEDNR 615
                    44444677888899**************999999***999988887774433 PP

>> Thioredoxin_2  Thioredoxin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.8   0.0    0.0012       2.1      14     102 ..      73     165 ..      63     172 .. 0.78
   2 !    9.6   0.3   0.00067       1.2       6      98 ..     286     356 ..     281     362 .. 0.74
   3 ?   -1.2   0.0       1.5   2.7e+03      66      90 ..     427     452 ..     382     459 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0012
  Thioredoxin_2  14 dpdCpyCkklkkelkelddvtvrvllfplkpsfepkavaiwcakekkkafkd.............ieenvelarkygvrgtPtiv.fldgkeivar 95 
                    +p+Cp C+++    ++l  ++++     ++++  p + +  ++++++ +++                + ++l  +++++++Pt+  + +g+  v++
     EEA21004.1  73 SPSCPHCQAIAPSWQTL--YEFY-----YTSD--PLSSSSTKSPDPQSSLNSftgyydfhfaemnCLAFRDLCVELDIKFFPTFSlYHNGE-LVEQ 158
                    899*********99999..7777.....6655..8888888888888555556669999999999889999************77366666.9999 PP

  Thioredoxin_2  96 lpGyvpa 102
                    + G+ + 
     EEA21004.1 159 YSGMKNM 165
                    9998665 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00067
  Thioredoxin_2   6 kpvlvvftdpdCpyCkklkkelkelddvtvrvllfplkpsfepkavaiwcakekkkafkdieenvelarkygvrgtPtivfldgk..eivarlpG 98 
                     p +v f++p+C  C++l     ++    +      +k +    + ++ c+ ek            l +  gv+g Pt++f+ g       +++G
     EEA21004.1 286 DPWFVKFYAPWCHHCQALAPPWLTM---AKE-----MKGQ--LNVGEVNCDVEKR-----------LCKDAGVKGYPTMFFFKGGekV---EYQG 356
                    6778889999999999999988888...333.....3333..6677888888886...........9999********9999998422...4444 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 1.5
  Thioredoxin_2  66 ieenvelarkygvrgtPt.ivfldgk 90 
                    +++++ la++++++  P  +v+ dg+
     EEA21004.1 427 KTDSEILADRFKISTWPRlLVVRDGR 452
                    45666688999999999977799998 PP

>> Thioredoxin_8  Thioredoxin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.0     0.086   1.5e+02       6      30 ..      69      93 ..      64     148 .. 0.89
   2 !    8.1   0.0    0.0018       3.2       5      46 ..     289     328 ..     285     335 .. 0.82
   3 ?    1.0   0.0      0.31   5.6e+02      59      91 ..     315     348 ..     307     352 .. 0.71
   4 ?    3.2   0.0     0.063   1.1e+02      68      90 ..     427     449 ..     384     453 .. 0.80

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.086
                   EEE--SSSHHHHHHHHHHHHHHHHH CS
  Thioredoxin_8  6 Lyfgaswcppckaftpklkelyekl 30
                   +  ++  cp+c+a+ p+ + lye +
     EEA21004.1 69 VKHFSPSCPHCQAIAPSWQTLYEFY 93
                   6668889**********99999987 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0018
                    EEEE--SSSHHHHHHHHHHHHHHHHHHHTTSEEEEEEE-SS- CS
  Thioredoxin_8   5 lLyfgaswcppckaftpklkelyeklkkkkkveivyvsldkk 46 
                    ++ f+a wc++c+a  p    + +++k   ++++  v++d +
     EEA21004.1 289 FVKFYAPWCHHCQALAPPWLTMAKEMK--GQLNVGEVNCDVE 328
                    689*************99999999998..7888877777765 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 0.31
                    TTSEE.EE-TT-.HHHHTT-S--TT-SEEEEE-T CS
  Thioredoxin_8  59 kpwlsvpfddkk.rnklkkkynvkaiPtlvvldk 91 
                    k  l+v   +++  + l+k  +vk++Pt++  + 
     EEA21004.1 315 KGQLNVGEVNCDvEKRLCKDAGVKGYPTMFFFKG 348
                    5555555555555889*************98765 PP

  == domain 4  score: 3.2 bits;  conditional E-value: 0.063
                    TT-HHHHTT-S--TT-SEEEEE- CS
  Thioredoxin_8  68 dkkrnklkkkynvkaiPtlvvld 90 
                    + +++ l+++++++ +P+l+v++
     EEA21004.1 427 KTDSEILADRFKISTWPRLLVVR 449
                    4567889*************997 PP

>> HyaE  Hydrogenase-1 expression protein HyaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0     0.048        87      69      96 ..     325     352 ..     310     362 .. 0.82
   2 !   11.4   0.0   0.00013      0.24      70      94 ..     428     452 ..     415     461 .. 0.88
   3 ?   -2.5   0.0       2.7   4.9e+03       8      39 ..     578     616 ..     573     622 .. 0.72

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.048
                 HHHHHHHHHCCT-TSSSEEEEEETTEEE CS
        HyaE  69 reqeealaerfgvlktPsllflrdgeyl 96 
                  + e++l +  gv+ +P++ f+++ge +
  EEA21004.1 325 CDVEKRLCKDAGVKGYPTMFFFKGGEKV 352
                 46789999***************99865 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00013
                 HHHHHHHHCCT-TSSSEEEEEETTE CS
        HyaE  70 eqeealaerfgvlktPsllflrdge 94 
                  ++e la+rf+++ +P ll++rdg+
  EEA21004.1 428 TDSEILADRFKISTWPRLLVVRDGR 452
                 789********************97 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 2.7
                 T.TEEEE-CCCHHHHHHH.......HSEEEEEESS-SS- CS
        HyaE   8 rkglaevdadtlddflka.......agdavlllagDpkr 39 
                 +  +a+vd d  d++l++        g  v++   D +r
  EEA21004.1 578 QVAFAWVDGDFWDRWLRTtygidvkDGERVIINDEDNRR 616
                 667899999999999998666666666666666666666 PP

>> Thioredoxin_7  Thioredoxin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.1      0.86   1.5e+03      26      35 ..      73      82 ..      68      84 .. 0.78
   2 ?   11.6   0.1   0.00014      0.25      16      36 ..     284     304 ..     278     347 .. 0.75
   3 ?   -3.0   0.0       4.9   8.8e+03      45      64 ..     490     509 ..     486     516 .. 0.72

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.86
                   -TT-HHHHHH CS
  Thioredoxin_7 26 aswcftCqal 35
                   +  c++Cqa+
     EEA21004.1 73 SPSCPHCQAI 82
                   568*****97 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 0.00014
                    HT--EEEEE--TT-HHHHHHH CS
  Thioredoxin_7  16 rgkpvlvffgaswcftCqale 36 
                    +  p +v f a wc++Cqal+
     EEA21004.1 284 TRDPWFVKFYAPWCHHCQALA 304
                    567889*************96 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 4.9
                    HHH.HHHT-EEEEESS--S- CS
  Thioredoxin_7  45 vkaalaekfvllrvdvterd 64 
                     k+++++k+v+l +    r+
     EEA21004.1 490 AKEIMQNKYVVLGILSHKRS 509
                    68889999999877665554 PP

>> Calsequestrin  Calsequestrin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.3   0.00015      0.27      95     192 ..     319     417 ..     308     439 .. 0.77
   2 ?   -2.1   0.0      0.85   1.5e+03      41      74 ..     484     518 ..     481     530 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00015
                    EEEEEETTTTHHHHHCCT--STTEEEEEETTCEEEE-S--SHHHHHHHHHCCCS-SEEE..E-SHHHHHHHHH--SS-EEEEE-S-TTSHHHHHHH CS
  Calsequestrin  95 gfvlvdakkeaklakklgldevdslyvlkgdevieydgefaadvlveflldlledpvel..iesklelqaferiedeikligyfkskeseyykafe 188
                      + v+++ e +l+k  g++   +++ +kg e +ey+g      l+ +    ++    +  +++    + +e+  + i l  + k+  se + a+e
     EEA21004.1 319 NVGEVNCDVEKRLCKDAGVKGYPTMFFFKGGEKVEYQGLRGVGDLISYAQKAVDTGAGVkyVDAS-TFKEMEETGEVIFLYFFDKATTSEDFAALE 413
                    455677777889****************************9999999999998876554104433.4566666666777777779999******99 PP

                    HHHH CS
  Calsequestrin 189 eaae 192
                    + a 
     EEA21004.1 414 QLAL 417
                    9875 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.85
                    EE-CCCHHHHHC.C-SEEEEEEE--STTSCCCCHH CS
  Calsequestrin  41 slteknyknvlk.kyevlallyhesveddkvaqkq 74 
                    +lt  n k++++ ky vl +l h+ +++ +  q +
     EEA21004.1 484 ELTVSNAKEIMQnKYVVLGILSHKRSDEFRLGQAE 518
                    57778999988549*********987776666543 PP

>> Thioredoxin_3  Thioredoxin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.0      0.12   2.2e+02       6      20 ..      72      86 ..      69      93 .. 0.77
   2 ?    7.0   0.0    0.0034       6.1       7      62 ..     294     355 ..     290     362 .. 0.81

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.12
                   ESSSSTTCHHHHHHH CS
  Thioredoxin_3  6 lgpgCakCpklekav 20
                   ++p+C++C++++  +
     EEA21004.1 72 FSPSCPHCQAIAPSW 86
                   799*****9876555 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0034
                    SSSSTTCHHHHHHHHHHCHCCTCECEEECC.TTHHHH..HHCT-SSSSEE.ECT..TCEEEE CS
  Thioredoxin_3   7 gpgCakCpklekavkeaaaekgikaevekv.tdfeei..ekygVmsvPal.vid..gkvvvs 62 
                     p C++C++l+  +  +a+e++ +++v +v  d+e+   ++ gV   P++ +    +kv+++
     EEA21004.1 294 APWCHHCQALAPPWLTMAKEMKGQLNVGEVnCDVEKRlcKDAGVKGYPTMfFFKggEKVEYQ 355
                    577**************************987888766999999999998433344555555 PP

>> Fungus-induced  Fungus-induced protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.7   7.4e-05      0.13      10      44 ..     677     710 ..     673     714 .. 0.77
   2 ?   -4.4   1.8        10   1.8e+04      32      40 ..     714     722 ..     706     723 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 7.4e-05
  Fungus-induced  10 aiLaissVsgifkp.kggkrcgrGgsgyGsGseegv 44 
                     +iL+iss+++   + +++++ +rG s yGs   +g+
      EEA21004.1 677 IILVISSIAA--YIaHRRRQLRRGLSAYGSNNGGGI 710
                     79********..553455555*********655655 PP

  == domain 2  score: -4.4 bits;  conditional E-value: 10
  Fungus-induced  32 GgsgyGsGs 40 
                     G s +GsG+
      EEA21004.1 714 GTSTGGSGG 722
                     666667764 PP

>> TraF  F plasmid transfer operon protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0     0.063   1.1e+02     131     155 ..      66      90 ..      60      95 .. 0.77
   2 ?   -1.4   4.2      0.95   1.7e+03      16      63 ..     203     250 ..     189     255 .. 0.69
   3 ?    5.5   0.0    0.0076        14     135     170 ..     291     328 ..     278     352 .. 0.75
   4 ?   -3.4   0.0       3.8   6.7e+03     184     202 ..     433     451 ..     425     455 .. 0.75

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.063
        TraF 131 ygLlfFyrgkcpyceaqapilqafa 155
                 y ++  ++++cp c+a ap+ q + 
  EEA21004.1  66 YWFVKHFSPSCPHCQAIAPSWQTLY 90 
                 555556899**********999876 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.95
        TraF  16 kekakppkaakpalkeptseesatesaaelrkeleelldkAilnPtee 63 
                 +++  p++++k  ++ ++ +e+++e++++ ++++++ + kA ++ + +
  EEA21004.1 203 EKPDVPQAKDKDPAAGAKAAENYNEKVSQSTETIDKEESKAADTTSTK 250
                 22233333333333566889999*************999999877655 PP

  == domain 3  score: 5.5 bits;  conditional E-value: 0.0076
        TraF 135 fFyrgkcpyceaqapilqafadky..glevraVsvdgr 170
                  Fy++ c  c+a+ap    +a+++  +l v  V++d +
  EEA21004.1 291 KFYAPWCHHCQALAPPWLTMAKEMkgQLNVGEVNCDVE 328
                 59********************9955577777777755 PP

  == domain 4  score: -3.4 bits;  conditional E-value: 3.8
        TraF 184 qaarlgvkrtPalvlvdpk 202
                  a r+++++ P l++v+  
  EEA21004.1 433 LADRFKISTWPRLLVVRDG 451
                 4569*********999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (743 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1010  (0.0563333); expected 358.6 (0.02)
Passed bias filter:                      625  (0.0348597); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.76u 0.33s 00:00:01.09 Elapsed: 00:00:00.51
# Mc/sec: 4411.94
//
Query:       EEA21005.1  [L=569]
Description: amino acid permease [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      2e-69  234.5  48.7    2.3e-69  234.3  48.7    1.0  1  AA_permease_2  Amino acid permease
    3.3e-18   65.5  35.3    4.6e-18   65.1  35.3    1.2  1  AA_permease    Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  234.3  48.7   2.6e-73   2.3e-69       1     423 [.      56     502 ..      56     504 .. 0.91

  Alignments for each domain:
  == domain 1  score: 234.3 bits;  conditional E-value: 2.6e-73
  AA_permease_2   1 lsllsafalvigsvigsgifvkn...laasggpalilwvwiavligslavllvyaElssalprsgGiyvytkaa....fgkkvaflsawfnwfayv 89 
                    +sl+++f++++ ++  +++f+++   +++++g+  ++w+w+++++++ +v+ ++aEl+sa+p+sgG+y  ++ +    +g+++a++++w+nw+++v
     EEA21005.1  56 FSLWTTFCVSFAVLGLLPSFASTlyyGMGYAGTGGMVWGWLIAMVFIQCVAMAMAELCSAMPTSGGLYYAAAVLappgYGPFAAWITGWSNWIGQV 151
                    79************9999999999999******************************888********999988555559**************** PP

  AA_permease_2  90 pvlasilsvaasyllna...lgpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfsslstetdtf 182
                     +++s+ +++a+++l a   ++pd++++tw+tyl+ ++ili++++i+++ +k++a+i++++ +++i+ ++i+li ++ +t ++  f+s+ + ++t+
     EEA21005.1 152 TSAPSVDYALAAMILAAgsiANPDYVPTTWQTYLLTVFILIIHTVISSMPTKWIATINSWGSTFNIIALVITLITIPAATSNIPKFTSAKDVWGTI 247
                    **************777555789********************************************9******************9875555554 PP

  AA_permease_2 183 fpn..gwpgv..llgllivlwsfdGfesaanvsee..vkkkdvpkaifigllivlvlyllvniaflgvvpddeianlsnlgsvaalffeavggkvv 272
                     ++    +gv  l+++ +v+w+++G++s  + see  + +   p+ai +  ++ ++l++++++++++ v+d     +s+lg+++a ++ +v  +  
     EEA21005.1 248 YNGtdYPDGVaiLMSFVGVIWTMSGYDSPFHLSEEcsNANIASPRAITMTSAVGGLLGWFLQLVVAYTVTDIDSVISSDLGQPWASYLLQVLPQQT 343
                    44333566645599*********************5444579*****************************88888999*****999999998999 PP

  AA_permease_2 273 aiivvilialsllgaintavigssrvlealardgvlP..rffakvn.kfgspiraiiltaivslillllfllassaaynfllsvsslgliisylll 365
                    a+++ +l++++ + ++ ++++++srv +a ard+++P    +++vn ++++p++a++l++++  il++l++++ + a+ +l+s+++++ +i ++++
     EEA21005.1 344 AMAILALTIVCGFSMGQGCMVAASRVTYAYARDDCFPlsGLWKQVNpRTQTPVNAVVLNCVLG-ILMCLLIFGGTVAIGALFSIGAIAQFIAFAIP 438
                    999999*********************************************************.55566667779********************* PP

  AA_permease_2 366 iigalilrkkrphlkrpgk....ilvaiigalfllfllvalffppkgpa..tqssliytiiltv 423
                    i+ ++++  +r + + +       +++++ga f++++l +l++p+++ +  t + +++t+++++
     EEA21005.1 439 IAIRVFIVGDRFKPGPWNLgkmsKPIGATGAMFVFLMLPILCLPSVTGNdlTADLMNWTCLVYG 502
                    ********99998866443334469********************9887789999****99876 PP

>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.1  35.3   5.2e-22   4.6e-18      18     385 ..      78     440 ..      62     490 .. 0.80

  Alignments for each domain:
  == domain 1  score: 65.1 bits;  conditional E-value: 5.2e-22
  AA_permease  18 glgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfyt....yasrflgpelGfviGlnylfswitvlaleltaasiliqfwel..vtd 109
                   l++  + aG +g++ ++l+a+v+i +v+++++e+ +++p sgg y+    +a    gp +++ +G++ ++ ++t ++    a++ +i  +++  ++d
   EEA21005.1  78 TLYYGMGYAGTGGMVWGWLIAMVFIQCVAMAMAELCSAMPTSGGLYYaaavLAPPGYGPFAAWITGWSNWIGQVTSAPSVDYALAAMILAAGSiaNPD 175
                  57889999********************************9999885333378888999999999999******999976444443333333312555 PP

  AA_permease 110 .lpkawvt..gavflvvl.liinlvgvkvygeaefilalikiiaiiafiivg.iillaggkpnkgagfrflgdngsifknnlppgfakeeegafknfi 202
                   +p++w t   +vf++++ ++i+ +  k+ + +  + + + iia+++++i   + ++   k      f++ +d ++    ++ +g++ +++    +++
   EEA21005.1 176 yVPTTWQTylLTVFILIIhTVISSMPTKWIATINSWGSTFNIIALVITLITIpAATSNIPK------FTSAKDVWG----TIYNGTDYPDG---VAIL 260
                  256666666666666555466788889**********************988433333333......355566666....45555333333...79** PP

  AA_permease 203 svfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasaaspfvifikesgvsvlaplinaviltaa 300
                  + fv v+ +++G+ +   +++E+++   + P+ai ++    +++  ++ l++  +v + d  + +d  ++     +++        a  i a++++  
   EEA21005.1 261 MSFVGVIWTMSGYDSPFHLSEECSNANIASPRAITMTSAVGGLLGWFLQLVVAYTVTDIDSVISSDLGQP---WASYLLQVLPQQTAMAILALTIVCG 355
                  *********************************************9999999999999998888888877...7777777777777888888888888 PP

  AA_permease 301 lssansslysasRvlyslakdglaP...kvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliil 385
                  +s++ +++++asRv y++a+d+ +P    + ++  + + P++a++l ++++ l+ l   l ++ ++++  l +i a++++i + + i+
   EEA21005.1 356 FSMGQGCMVAASRVTYAYARDDCFPlsgLWKQVNPRTQTPVNAVVLNCVLGILMCL---LIFGGTVAIGALFSIGAIAQFIAFAIPIA 440
                  9**************************88888889**************9988883...44444489999999999999999987665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (569 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       704  (0.039266); expected 358.6 (0.02)
Passed bias filter:                      279  (0.0155614); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.56
# Mc/sec: 3086.42
//
Query:       EEA21006.1  [L=70]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-22   79.0   0.4    2.2e-22   78.9   0.4    1.1  1  QCR10     Ubiquinol-cytochrome-c reductase complex subunit (Q


Domain annotation for each model (and alignments):
>> QCR10  Ubiquinol-cytochrome-c reductase complex subunit (QCR10)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.9   0.4   1.2e-26   2.2e-22      13      63 .]      20      70 .]       7      70 .] 0.94

  Alignments for each domain:
  == domain 1  score: 78.9 bits;  conditional E-value: 1.2e-26
       QCR10 13 gptlalfGgaagvavlfftsgvPrvqkdiLqkiPvigsyfkkeippeDnpF 63
                ++++ +fG+aag++++ff+++vPrv+kdiLqk+P++++y ++++ppeD+pF
  EEA21006.1 20 ATIASGFGVAAGIFAVFFFGEVPRVRKDILQKLPFFDKYLDRTVPPEDSPF 70
                7899**********************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (70 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       331  (0.0184617); expected 358.6 (0.02)
Passed bias filter:                      274  (0.0152825); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.35s 00:00:00.92 Elapsed: 00:00:00.58
# Mc/sec: 362.70
//
Query:       EEA21007.1  [L=98]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      5e-25   87.3   1.1    6.7e-25   86.9   1.1    1.2  1  QCR10     Ubiquinol-cytochrome-c reductase complex subunit (Q


Domain annotation for each model (and alignments):
>> QCR10  Ubiquinol-cytochrome-c reductase complex subunit (QCR10)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.9   1.1   3.8e-29   6.7e-25       2      63 .]      37      98 .]      36      98 .] 0.99

  Alignments for each domain:
  == domain 1  score: 86.9 bits;  conditional E-value: 3.8e-29
       QCR10  2 ggitlktltrygptlalfGgaagvavlfftsgvPrvqkdiLqkiPvigsyfkkeippeDnpF 63
                +g+t+ ++t++++++ +fG+aag++++ff+++vPrv+kdiLqk+P++++y ++++ppeD+pF
  EEA21007.1 37 HGLTIPKVTKAATIASGFGVAAGIFAVFFFGEVPRVRKDILQKLPFFDKYLDRTVPPEDSPF 98
                79***********************************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (98 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       405  (0.0225891); expected 358.6 (0.02)
Passed bias filter:                      350  (0.0195214); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.36u 0.27s 00:00:00.63 Elapsed: 00:00:00.42
# Mc/sec: 700.97
//
Query:       EEA21008.1  [L=70]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-22   79.0   0.4    2.2e-22   78.9   0.4    1.1  1  QCR10     Ubiquinol-cytochrome-c reductase complex subunit (Q


Domain annotation for each model (and alignments):
>> QCR10  Ubiquinol-cytochrome-c reductase complex subunit (QCR10)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.9   0.4   1.2e-26   2.2e-22      13      63 .]      20      70 .]       7      70 .] 0.94

  Alignments for each domain:
  == domain 1  score: 78.9 bits;  conditional E-value: 1.2e-26
       QCR10 13 gptlalfGgaagvavlfftsgvPrvqkdiLqkiPvigsyfkkeippeDnpF 63
                ++++ +fG+aag++++ff+++vPrv+kdiLqk+P++++y ++++ppeD+pF
  EEA21008.1 20 ATIASGFGVAAGIFAVFFFGEVPRVRKDILQKLPFFDKYLDRTVPPEDSPF 70
                7899**********************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (70 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       331  (0.0184617); expected 358.6 (0.02)
Passed bias filter:                      274  (0.0152825); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.27s 00:00:00.68 Elapsed: 00:00:00.45
# Mc/sec: 471.91
//
Query:       EEA21009.1  [L=707]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.9e-06   26.3   8.1      1e-05   25.5   8.1    1.4  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.5   8.1   5.7e-10     1e-05       2      36 ..      15      52 ..      14      56 .. 0.89

  Alignments for each domain:
  == domain 1  score: 25.5 bits;  conditional E-value: 5.7e-10
                S-HHHHHCT---ST...SSSS.-HHHHHCTHHHCCCCTC CS
     Zn_clus  2 aCdnCrkkKvKCda...kkPa.CsnCkklnleCtfyses 36
                aCd+C++ K KC +   +++  C++C+k ++ C+ ys s
  EEA21009.1 15 ACDRCHSFKLKCPRsslRNEDtCARCRKAGVSCS-YSPS 52
                9***************966666************.8876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (707 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       530  (0.029561); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.24s 00:00:00.85 Elapsed: 00:00:00.42
# Mc/sec: 4998.89
//
Query:       EEA21010.1  [L=361]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
     0.0001   21.9   0.0    0.00022   20.8   0.0    1.6  1  DUF676         Putative serine esterase (DUF676)
      0.003   17.3   0.0     0.0049   16.6   0.0    1.4  1  PGAP1          PGAP1-like protein
  ------ inclusion threshold ------
      0.057   13.0   0.1      0.093   12.4   0.1    1.2  1  Abhydrolase_8  Alpha/beta hydrolase
      0.076   12.2   0.0      0.091   11.9   0.0    1.3  1  LCAT           Lecithin:cholesterol acyltransferase
      0.098   13.2   0.0       0.13   12.9   0.0    1.3  1  Abhydrolase_6  Alpha/beta hydrolase family
       0.13   12.9  10.6       0.26   12.0  10.6    1.4  1  GRP            Glycine rich protein family


Domain annotation for each model (and alignments):
>> DUF676  Putative serine esterase (DUF676)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8   0.0   7.4e-08   0.00022      10     163 ..      61     219 ..      58     265 .. 0.65

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 7.4e-08
      DUF676  10 lvHGlqgn.saDl..elikeqleki..keklpeekieflmsen....nesktfkgidvlgerlaeevlevvkkkkdknkkiSfvghSlGgliaraaiak 99 
                 +vHGl gn ++ +  e   e + k+   +++ + +i+  ++ +    +++ + + ++  +++l++ +     + + ++  + fv+hSlGgl+ + a+  
  EEA21010.1  61 FVHGLTGNrESTWtaEGKPEPWPKAllPSEIGNARIITFGYDAyvvrASAASKNHLRDHADNLVNALTVDRARINASTRALIFVAHSLGGLVCKKALLS 159
                 7777777753333332223334444444556666666666654111133344455666677777776655555555577899***************96 PP

      DUF676 100 lkekemt.lkeaikglepvtfitlasPhLGvlysskslinlglalleklkkslsmeqlgltGrdL 163
                  + + ++ l++++k  + + f+   +Ph G+   + + +  +l   + +k+ ++++ l + Gr +
  EEA21010.1 160 SRVNGEAdLRGIFKSTKGIIFM--GTPHEGSWAANWAIFPAKLL--SLIKS-TNINLLDTLGRVM 219
                 5544433578899999999886..79****99999885555544..33433.4555555555555 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   1.6e-06    0.0049      53     133 ..     104     189 ..      55     225 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 1.6e-06
       PGAP1  53 fneelsaldGrtlldqaeylndaIkyIlslysssekeptsviliGHSmGGivaraaltlkn........yikqsvntiltlasPhalpp 133
                 +  + sa   + l+d+a+ l +a+       +  +  ++ +i ++HS+GG+v + al   +         i +s + i+ +++Ph+ + 
  EEA21010.1 104 YVVRASAASKNHLRDHADNLVNALTVDR---ARINASTRALIFVAHSLGGLVCKKALLSSRvngeadlrGIFKSTKGIIFMGTPHEGSW 189
                 4557788889999999999888887733...355888999***************9999887777887766788999999999998765 PP

>> Abhydrolase_8  Alpha/beta hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   3.1e-05     0.093      64     134 ..      94     162 ..      84     170 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 3.1e-05
  Abhydrolase_8  64 AviAWlgYeaPagaskevatddrAaagAaeLnallrdlratsvpgqhlallgHSYGSlvaslAlddaaseV 134
                    A i   gY+a +  +  + +++  +++   +nal  d ++++++ + l  ++HS G lv+  Al +  s+V
     EEA21010.1  94 ARIITFGYDAYVVRASAASKNHLRDHADNLVNALTVDRARINASTRALIFVAHSLGGLVCKKALLS--SRV 162
                    677778999997777777777777777777799999999999999999999************976..555 PP

>> LCAT  Lecithin:cholesterol acyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0     3e-05     0.091     111     169 ..     128     192 ..      95     301 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 3e-05
        LCAT 111 lieealk.lsgkkvvliaHSmGnllvlyflkwveaea.....WvdqhikafislgapllGsvkav 169
                 +++ a   +s +  + +aHS+G+l++   l++ + ++      + +  k++i +g+p  Gs  a 
  EEA21010.1 128 TVDRARInASTRALIFVAHSLGGLVCKKALLSSRVNGeadlrGIFKSTKGIIFMGTPHEGSWAAN 192
                 5666666567778899***************999888778886668899***********98775 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   4.3e-05      0.13      46      78 ..     114     158 ..      61     263 .. 0.58

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 4.3e-05
                    -HHHCHHH.HHHHCCTT.........TTSEEEEEETCHHH......H CS
  Abhydrolase_6  46 dledladl.aalldelaa.......gggpvvlvGHSlGGa......l 78 
                    ++  l+d  ++l+++l         ++++ + v+HSlGG+      l
     EEA21010.1 114 NH--LRDHaDNLVNALTVdrarinaSTRALIFVAHSLGGLvckkalL 158
                    22..33332333333322333555567888*********94442222 PP

>> GRP  Glycine rich protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0  10.6   8.7e-05      0.26      33      91 ..     283     350 ..     268     354 .. 0.51

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 8.7e-05
         GRP  33 ksekeeevkdekyggggkh..........ggGgygggggggngGGGykgggGgygggggggeggyGgGy 91 
                 k+e+++   d+++     +           g  ++g+ +++n GGG ++ g  y+ g   +++g G+ +
  EEA21010.1 283 KEETAKALADQQQQQHEGTkrpgdanpgqSGNQHTGNTYNYNSGGG-NQSGNTYQSGNTSYNSGSGHQF 350
                 3333322222222111111233445565455667788888877877.5666778887777776555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (361 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       503  (0.0280551); expected 358.6 (0.02)
Passed bias filter:                      345  (0.0192426); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 2411.24
//
Query:       EEA21011.1  [L=556]
Description: hypothetical protein PMAA_048150 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      0.006   16.5   0.0        4.2    7.3   0.0    2.5  2  NACHT     NACHT domain
  ------ inclusion threshold ------
       0.14   12.5   0.1       0.84   10.0   0.1    2.1  1  AAA_16    AAA ATPase domain


Domain annotation for each model (and alignments):
>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.3   0.0   0.00047       4.2       2      27 ..      12      37 ..      11      47 .. 0.83
   2 !    6.7   0.0   0.00068       6.1      35     111 ..      78     188 ..      65     246 .. 0.71

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.00047
                CEEEEC-TTTCHHHHHHHHHHHHCTS CS
       NACHT  2 lvilqGeaGsGKTtLlqklalawaeg 27
                l++++G++ sGK+tL+++  ++ +++
  EEA21011.1 12 LLWIKGKPVSGKSTLMRWAFDERKKN 37
                58***************988776665 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.00068
                 SEEEEEETTTTTTS-...-HCHHHCCCCTS--SSS-C............................CHHHHCCSCCCEE..........EEEE-STT-SS CS
       NACHT  35 klvFflslrelsrsgnarsladllfsqlpepaapvse............................vwavllelperlL..........lilDglDelvt 95 
                  l+Ff++ r  s +++++++ +++  ql+e+++  +e                             ++ l++ ++++L          l +D+lDe+ +
  EEA21011.1  78 ILSFFFHGRGSSLQKTMLGFYRTVLFQLLEEQSIREEkiealsnlekffktqcdsrgppgiswqwEMSQLAQDFQSALteilkghlvyLYVDALDECGE 176
                 5677777777777777766555555555555555555566667777777777777777777777767778888888889999999999**********9 PP

                 -TCH.........HHH CS
       NACHT  96 dlgqkekqpvrtlLse 111
                 d+      ++ + + +
  EEA21011.1 177 DDAR----HLTETFVK 188
                 7766....33333333 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.1   9.3e-05      0.84      23     154 ..       9     181 ..       5     195 .. 0.60

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 9.3e-05
      AAA_16  23 rpelvllsGesGvGKsslvrellralekd.........................................ggiflrgkcdqlesaipy....sa.laqa 75 
                 +++l+ + G + +GKs+l+r ++++ +k+                                           +f+ g+  +l+   ++     + l q+
  EEA21011.1   9 DGGLLWIKGKPVSGKSTLMRWAFDERKKNpdnrnestndheqstdnlkgnvgdqkkstdsknpelkksiiLSFFFHGRGSSLQ--KTMlgfyRTvLFQL 105
                 45789999***********9999877777888888888888888887777766666666666666643321222333333331..12212222213333 PP

      AAA_16  76 lareellrqlldeaesaeleawrekleealaavpelagaea.....srllellkrllallsrderplvlvlDdlqwadeaslql 154
                 l +e+ +r+++ ea s++   ++++++++       ++ ++     s+l++ ++++l  + + ++ ++l +D l+   e+++  
  EEA21011.1 106 L-EEQSIREEKIEALSNLEKFFKTQCDSR------GPPGISwqwemSQLAQDFQSALTEILK-GHLVYLYVDALDECGEDDARH 181
                 3.445555555554443333333333332......234444677799999999999966666.6779999**999888766554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (556 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       804  (0.0448435); expected 358.6 (0.02)
Passed bias filter:                      519  (0.0289475); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.30s 00:00:00.97 Elapsed: 00:00:00.50
# Mc/sec: 3334.60
//
Query:       EEA21012.1  [L=420]
Description: C2H2 transcription factor (RfeC), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.2e-05   25.5   1.4    1.2e-05   25.5   1.4    2.9  3  zf-H2C2_2    Zinc-finger double domain
    0.00021   21.5   4.4    0.00036   20.8   4.4    1.3  1  zf-Di19      Drought induced 19 protein (Di19), zinc-binding
    0.00026   21.6  15.2      0.023   15.5   5.9    2.6  2  zf-C2H2_4    C2H2-type zinc finger
  ------ inclusion threshold ------
      0.033   14.6  14.7       0.14   12.7   7.3    2.5  2  zf-C2H2      Zinc finger, C2H2 type
      0.049   13.9   4.0        3.3    8.1   0.8    2.3  2  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding


Domain annotation for each model (and alignments):
>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.0   0.8    0.0023       8.2      14      26 .]     231     243 ..     226     243 .. 0.87
   2 !   25.5   1.4   3.3e-09   1.2e-05       1      25 [.     246     270 ..     246     271 .. 0.95
   3 ?   -3.1   0.1       3.8   1.4e+04       2       7 ..     275     280 ..     275     281 .. 0.79

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0023
   zf-H2C2_2  14 pyeCplCdkaFkt 26 
                 ++ Cp C k++ +
  EEA21012.1 231 KFPCPHCTKTYLH 243
                 599*******976 PP

  == domain 2  score: 25.5 bits;  conditional E-value: 3.3e-09
   zf-H2C2_2   1 nLrrHirkHtgekpyeCplCdkaFk 25 
                 +L+rH+  Htg++py C lC+++F+
  EEA21012.1 246 HLKRHLLRHTGDRPYMCVLCKDTFS 270
                 79**********************8 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 3.8
   zf-H2C2_2   2 LrrHir 7  
                 L+rH+ 
  EEA21012.1 275 LKRHFQ 280
                 899*86 PP

>> zf-Di19  Drought induced 19 protein (Di19), zinc-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8   4.4     1e-07   0.00036       2      46 ..     231     275 ..     230     285 .. 0.81

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 1e-07
     zf-Di19   2 sftCPyCgk.eltvkeLveHvedeHrveskevvCPvCaekvtk.dlv 46 
                 +f+CP+C+k  l++k L +H+   H+ + ++++C +C+++ ++ d+ 
  EEA21012.1 231 KFPCPHCTKtYLHAKHLKRHLLR-HTGD-RPYMCVLCKDTFSRsDIL 275
                 69*******78**********98.8876.6799*****987653544 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   5.9   6.4e-06     0.023       1      23 [.     232     254 ..     232     255 .. 0.97
   2 !   11.1   1.9   0.00016      0.58       1      22 [.     260     281 ..     260     283 .. 0.89

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 6.4e-06
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlkth 23 
                 f+Cp+C+k++   k+L+rHl++h
  EEA21012.1 232 FPCPHCTKTYLHAKHLKRHLLRH 254
                 89********************9 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00016
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlkt 22 
                 + C +C+ +Fs+++ L+rH+++
  EEA21012.1 260 YMCVLCKDTFSRSDILKRHFQK 281
                 78********88888****986 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   7.3   3.9e-05      0.14       1      23 []     232     254 ..     232     254 .. 0.98
   2 ?    6.3   0.7    0.0041        15       1      21 [.     260     280 ..     260     281 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 3.9e-05
                 EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirtH 23 
                 ++Cp+C+k++ +  +LkrH+ +H
  EEA21012.1 232 FPCPHCTKTYLHAKHLKRHLLRH 254
                 89********************9 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0041
                 EEETTTTEEESSHHHHHHHHH CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHir 21 
                 y C  C+ +F+r++ LkrH +
  EEA21012.1 260 YMCVLCKDTFSRSDILKRHFQ 280
                 89*****************65 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.8   0.00093       3.3       1      21 [.     231     251 ..     231     252 .. 0.94
   2 ?    6.7   0.1    0.0025       9.1       2      21 ..     260     279 ..     259     280 .. 0.92

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00093
                  ECBBTTTTBBBSSHHHHHCCT CS
  zf-C2H2_jaz   1 qfYCvlCdKyFksenaldnHl 21 
                  +f C++C K++  ++ l+ Hl
   EEA21012.1 231 KFPCPHCTKTYLHAKHLKRHL 251
                  688*****************7 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0025
                  CBBTTTTBBBSSHHHHHCCT CS
  zf-C2H2_jaz   2 fYCvlCdKyFksenaldnHl 21 
                  + CvlC+ +F+ +  l+ H+
   EEA21012.1 260 YMCVLCKDTFSRSDILKRHF 279
                  89**************9997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (420 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       597  (0.033298); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.48
# Mc/sec: 2610.66
//
Query:       EEA21013.1  [L=682]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-13   51.1  25.1    2.8e-09   36.9   8.4    2.5  2  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
    2.3e-08   33.4   0.0    4.2e-08   32.5   0.0    1.4  1  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.9   8.4   3.2e-13   2.8e-09       2      36 ..      21      55 ..      20      58 .. 0.90
   2 !   19.6   8.7   8.3e-08   0.00074       1      36 [.      81     114 ..      81     118 .. 0.88

  Alignments for each domain:
  == domain 1  score: 36.9 bits;  conditional E-value: 3.2e-13
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfyses 36
                +C+nCr++Kv+Cd+ +P+C++C +l+l+C+f ++s
  EEA21013.1 21 VCNNCRSRKVRCDRAQPVCGSCTRLQLDCSFQRQS 55
                6*****************************65554 PP

  == domain 2  score: 19.6 bits;  conditional E-value: 8.3e-08
                 SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus   1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfyses 36 
                 +aC +Cr  K KC++  P C +C++++l C+  ++ 
  EEA21013.1  81 RACGSCRAVKAKCSGIGP-CERCVSKRLACE-LENH 114
                 59****************.***********9.6554 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.5   0.0   4.7e-12   4.2e-08       3     205 ..     157     335 ..     155     389 .. 0.84

  Alignments for each domain:
  == domain 1  score: 32.5 bits;  conditional E-value: 4.7e-12
  Fungal_trans   3 rffsnfh.pqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLl 98 
                    +f+ ++  +f +lhkp++l++       +  + +p l+ +++a G ++ + +   + ++++ ++qe      + e+l     +  +  +++l  L+
    EEA21013.1 157 AYFETTSrILFVFLHKPTILVYW------SRGILDPNLIKCVVAFGVFLGNGPPDGQ-ATARAWMQEV-----QEETLR----RIGRHTITHLRILV 237
                   588888889999***********......99***************99999999998.5666677453.....555555....567778******** PP

  Fungal_trans  99 llelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddlwes 195
                   ll+ + +  +d   +++++ +a r+a +++++   +++g      l+   +es rRl wa++  D++++         + ++++++LPcdd+   e+
    EEA21013.1 238 LLSRFRFHAGDFGDAWNILALAARVAFTMRMN--YEHEG------LDCIVQESHRRLMWAIYHQDRLFSGGIADLQVCPVEKMHIRLPCDDR-SFEM 325
                   ********************************..66788......*******************************88**************.5555 PP

  Fungal_trans 196 ddaseetlve 205
                     as+   ++
    EEA21013.1 326 GIASKAGFLN 335
                   5555444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (682 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       479  (0.0267165); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.26s 00:00:00.86 Elapsed: 00:00:00.43
# Mc/sec: 4735.23
//
Query:       EEA21014.1  [L=522]
Description: sulfatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      5e-42  144.4   0.0    6.9e-42  143.9   0.0    1.2  1  Sulfatase     Sulfatase
    6.6e-05   21.7   0.0    9.4e-05   21.2   0.0    1.3  1  DUF229        Protein of unknown function (DUF229)
     0.0001   22.5   0.1     0.0004   20.6   0.1    1.9  2  DUF4976       Domain of unknown function (DUF4976)
      0.004   16.8   0.3       0.14   11.8   0.3    2.3  1  Phosphodiest  Type I phosphodiesterase / nucleotide pyrophosp


Domain annotation for each model (and alignments):
>> Sulfatase  Sulfatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  143.9   0.0   1.5e-45   6.9e-42       1     309 []      24     367 ..      24     367 .. 0.87

  Alignments for each domain:
  == domain 1  score: 143.9 bits;  conditional E-value: 1.5e-45
                 EEEEEEEESSE-TTGSGGGTTTSCS..SHHHHHHHHTSEEESSEE-SSSSHHHHHHHHHHSS-HHHHTHSSCCSTTTHHCTTTS-HHHHHHHHTT-EEE CS
   Sulfatase   1 pnvvliladdlgagdlglyggktat..tpnldrlaeeglrftnfysaaplcspsraalltgryphnsgvasntevgggglpqteatLpellkeaGYnta 97 
                 pn+v+ + d+l++++lg+  +  a   tpn+d+ +++g+++tn ++ a++cs+sr +++tg yph sg   +   + + + + e+++ + +ke+GY+ a
  EEA21014.1  24 PNYVIFMPDQLRYDSLGCTTDGNAGinTPNIDAFRRRGTLYTNCFTQASVCSQSRCSMFTGCYPHVSG---HRSLQ-NLIKPWEPNIFRSMKENGYHIA 118
                 8*************9988766654444***************************************99...33333.********************** PP

                 EEEES-SCCSGGGSHHC........CTTTSE.EEETSSSCHHTCCCCCCCCCECTCCCTTTTCSHHHHHHHHHHHHHHCCC.TSSEEEEEEE-TTSSST CS
   Sulfatase  98 aigkwhlgwssrqsvyk........nrgfdr.flgfptgsaalkdpekseyngevlrvppeggysddrlldealefllarn.dkpfflylatlapHapp 186
                 +  +   ++ +  +  +           f   f  +++g++ +k++  +  + ++lr+ ++   +d++++  al++l   + dkp++l++ +l pH p+
  EEA21014.1 119 CLAPRGDTFAPTVTELSateygfleTPEFTPkFARGSGGEDIDKENIWNRLFYKGLRNANQALDYDEAVVRSALKWLECPPdDKPWVLFMPLLFPHCPF 217
                 **********999966699999999444554477777777777777777777777777899****************66666***************** PP

                 CTCGGHTCCGSTTTTCCCCCCH...................................HHHHHHHHHHHHHHHHHHHHHHHHHHTTTGGGEEEEEEESSS CS
   Sulfatase 187 eapdeyakkyatffddgseaar...................................qlleaylnsveyvDdligrvlaaLeenglldntlvvftSDhg 250
                 +++++y  +y + ++      +                                   ++ ++y++++++ Dd+ gr+l++++e+gl+++t+ +f+ Dhg
  EEA21014.1 218 QVEEPYFSMYDRDKM------AsvvskpekktgyeprymkairerygtgrateeiwrEVKATYFGMITRLDDQFGRILNKVDELGLWKDTVTMFFTDHG 310
                 ******999866654......123334677888999999999999****************************************************** PP

                 SCCCGHHTTSSSCTTCSSSHHHHBEEEEEEETTTSHCEEECSEEEGGGHHHHHHHHTTE CS
   Sulfatase 251 asleesngplrggkganayeggtrvPllvwwpgekaprvseelvshiDlfptildlagi 309
                 + l++ +   ++      +e  +r Pl++++ g+ ++++ +  ++ +Dl+pt+l+  gi
  EEA21014.1 311 EYLGDHGLIEKWPS--GLSETLVREPLIIAGAGIPENKTINSMTEMVDLVPTMLEMSGI 367
                 ***66444444444..5999**********************************98875 PP

>> DUF229  Protein of unknown function (DUF229)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.0   2.1e-08   9.4e-05     281     348 ..     249     315 ..     216     440 .. 0.84

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 2.1e-08
      DUF229 281 ylrqflerysnsrlfgffwsnslshdkfnllealDedllkylkklekkgllentlvlllsDHGlrfgk 348
                 y++ + ery   r   ++w  +++  +f ++++lD+++ ++l k+++ gl ++t+ +++ DHG   g+
  EEA21014.1 249 YMKAIRERYGTGRATEEIWR-EVKATYFGMITRLDDQFGRILNKVDELGLWKDTVTMFFTDHGEYLGD 315
                 56666666666666666665.577899************************************76655 PP

>> DUF4976  Domain of unknown function (DUF4976)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0       1.3   5.8e+03       6      21 ..     374     389 ..     373     394 .. 0.78
   2 !   20.6   0.1   8.9e-08    0.0004      39      91 ..     428     478 ..     421     486 .. 0.86

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 1.3
     DUF4976   6 qGksllpllkgkkkke 21 
                 +Gks++p+l g+++k+
  EEA21014.1 374 NGKSWVPILVGDATKH 389
                 59*******9877665 PP

  == domain 2  score: 20.6 bits;  conditional E-value: 8.9e-08
     DUF4976  39 vkrhygvrteryklihfykdidewelyDlkkDpkelknlyddpeyeevvkelk 91 
                 v + +++r+e+y+ i  y+  +  elyD   D +e++nl  dp+y e++++ +
  EEA21014.1 428 VGKAISLRDEKYTYI--YRLYEPAELYDRVSDSHEMHNLAADPAYCELIAKYE 478
                 667889999***988..6667889***********************998865 PP

>> Phosphodiest  Type I phosphodiesterase / nucleotide pyrophosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   0.3     3e-05      0.14      86     233 ..     115     310 ..      26     316 .. 0.53

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3e-05
                   G.................................GGGCTT........S-HHHHHHHTHTTC.EEEESETTTTSEBTTCT.SC.TBHHSBTCT.... CS
  Phosphodiest  86 a.................................prwwqg........epiwdtaakarglk.aaalfwpgsevdystyyylvsetppryled.... 136
                   +                                 p++ +g        e iw ++  + gl+ a+ +      v +s  ++l+  +pp+   +    
    EEA21014.1 115 YhiaclaprgdtfaptvtelsateygfletpeftPKFARGsggedidkENIWNRLFYK-GLRnANQALDYDEAVVRSALKWLE--CPPDDK-Pwvlf 207
                   2444455555555555555555555555555555555444555555556666666666.666444333333444444444443..333331.22333 PP

                   .........CSTTSCHHHHHHHHHHHHHHHCHTHSHHHHHCT.SSESEEEEEEC..CCHHHHHHH-TT..SHHHHHHHHHHHHHHHHHHHHHHHTTG CS
  Phosphodiest 137 ........dfnakvpledkvdkavlqtwldaafakvvlekel.ekpdlllvyle..etDtvgHkfGpd..spevedalrrvDkaigdLlealdergl 220
                           +f+ ++p+ + +d++++ + ++++++k        ++p+++  + e  +t+++  ++ +   + + +  + r+D+  g++l+ +de gl
    EEA21014.1 208 mpllfphcPFQVEEPYFSMYDRDKMASVVSKPEKK------TgYEPRYMKAIREryGTGRATEEI-WRevKATYFGMITRLDDQFGRILNKVDELGL 297
                   33444444666666666666655555666666654......235565555544312566666666.75467779999******************** PP

                   TTTEEEEEEES-- CS
  Phosphodiest 221 saetniilvSDHG 233
                   +++t  + + DHG
    EEA21014.1 298 WKDTVTMFFTDHG 310
                   ************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (522 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       438  (0.0244297); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.30s 00:00:00.93 Elapsed: 00:00:00.50
# Mc/sec: 3131.57
//
Query:       EEA21015.1  [L=534]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-40  138.7  47.9    2.1e-40  138.7  47.9    2.1  2  MFS_1     Major Facilitator Superfamily
    4.8e-12   45.5  14.8    4.8e-12   45.5  14.8    2.6  2  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.7  47.9   2.3e-44   2.1e-40       2     351 ..      29     425 ..      28     427 .. 0.88
   2 ?   -2.3   0.1      0.18   1.6e+03     288     311 ..     489     512 ..     481     522 .. 0.54

  Alignments for each domain:
  == domain 1  score: 138.7 bits;  conditional E-value: 2.3e-44
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgag 100
                 + a+f+sa + +++++alp ++a++++ s s + ++ ++y l+  ++ +++  +sd +Gr+ v+l++++lf ++++++ f++s+ +l+ +r+lqG++ag
  EEA21015.1  29 YAALFISAVNTTTVTTALP-TIAKHFQ-STSGYTWVGAAYVLADTASGPVWTNFSDIWGRKVVFLMAVALFMVSSFVCGFSTSMGMLISGRALQGAAAG 125
                 5789***************.*******.9999******************************************88888855555************** PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee........... 188
                 a++ +++++i+d+f  ++r++++g+  + ++++ ++gp++gg++a+++gWr+++y + +++++ f+++ l++ + +p+ +  ++ +             
  EEA21015.1 126 AIMLLVNIVISDMFDMRRRTLYLGICDVIWAMSGAIGPVVGGAFAEYAGWRWIWYTNIPIAAVTFLVVCLFMDVHNPRTPIWRGLKAVdwlgsasllav 224
                 ******************************************************************88888844444444444444445699******* PP

       MFS_1 189 ........................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllag 247
                                                         +++++ p+ p  + ++++     ++++ +l +f+++g  ++lply  +  +l+  l++g
  EEA21015.1 225 tlmvllglniggeytdwtsskvlvliivglalsgvffsveAKVAKYPVMP-VQVFKNRSNAA-AIAIGALHAFAMMGPEYYLPLY-FQSSKLAQPLQSG 320
                 ***************99999999999999999999999988888888888.66666666554.66666666779999********.5666666358888 PP

       MFS_1 248 lllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllllvlvliGf.glgfvfpsllalasdlappeeagtasglfntag 345
                 ll   + ++  ++++++g +++ +gr ++ll+a+++l+++ +gl++   +s+ ++ ++++ +iG  g+g+   + l++++ +++++e++ta++  ++++
  EEA21015.1 321 LLGLPFVFLEGMGGIISGLVIHYTGRYNALLWAGAVLMTLGFGLLIDLKSSTGLAKIMIYQIIGAlGSGLLIQPPLVAIQANVSQQETATATSTLTFMR 419
                 555555555555599999999*****99999999999999999999888899999999***************************************** PP

       MFS_1 346 slggal 351
                 +l+ a+
  EEA21015.1 420 GLAQAV 425
                 **9987 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 0.18
       MFS_1 288 alglallavtssavllllvlvliG 311
                 +lg a++  +  a l++++++++G
  EEA21015.1 489 SLGNAWILYAGIAGLTIVASYFVG 512
                 444444444444444444444444 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.5  14.8   5.3e-16   4.8e-12      32     191 ..      43     196 ..      19     212 .. 0.84
   2 !    3.2   7.0    0.0035        32      45     119 ..     316     391 ..     288     444 .. 0.77

  Alignments for each domain:
  == domain 1  score: 45.5 bits;  conditional E-value: 5.3e-16
                 STT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTT CS
    Sugar_tr  32 fglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEi 130
                  ++  + +++ +s++ ++++ +++++  ++++ +   ++d++GRk ++l+a++lf+++++++++++   s+ +li gR l G ++G++  lv + is +
  EEA21015.1  43 TTALPTIAKHFQSTSGYTWVGAAYVLADTASGPVWTNFSDIWGRKVVFLMAVALFMVSSFVCGFST---SMGMLISGRALQGAAAGAIMLLVNIVISDM 138
                 22223333333378889*************************************************...****************************** PP

                 S-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS CS
    Sugar_tr 131 ApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllfl 191
                    + R    ++ ++ +++   ++ ++g +++++ +   wr+  + ++ +a + +++++++
  EEA21015.1 139 FDMRRRTLYLGICDVIWAMSGAIGPVVGGAFAEYAG---WRWIWYTNIPIAAVTFLVVCLF 196
                 ************************************...8888888888887777776653 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.0035
                 ..HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHH.HHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHH CS
    Sugar_tr  45 svlsglivsiflvGaiiGslfagllgdrfGRkkslli.aavlfvigavlqaaakgknsvevlivgRvlvGigvGla 119
                  ++sgl+   f++ + +G++++gl++++ GR ++ll  +avl+  g  l +  k+ + +  +++ +++  +g Gl 
  EEA21015.1 316 PLQSGLLGLPFVFLEGMGGIISGLVIHYTGRYNALLWaGAVLMTLGFGLLIDLKSSTGLAKIMIYQIIGALGSGLL 391
                 5678888888999999********************95667777777777777777999999999***99999975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (534 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       930  (0.0518713); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.46
# Mc/sec: 3460.82
//
Query:       EEA21016.1  [L=540]
Description: hypothetical protein PMAA_048200 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.7e-06   26.9   8.6    9.6e-06   25.6   8.6    1.7  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   8.6   5.3e-10   9.6e-06       2      34 ..      33      69 ..      32      74 .. 0.86

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 5.3e-10
                S-HHHHHCT---ST..SSSS...-HHHHHCTHHHCCCC CS
     Zn_clus  2 aCdnCrkkKvKCda..kkPa...CsnCkklnleCtfys 34
                aCd+Cr +K +C++   +P+   C++C+k +  Ct +s
  EEA21016.1 33 ACDRCRMQKLRCERdiWRPSlmpCKRCRKARIACT-IS 69
                9*************996666666************.54 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (540 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       700  (0.0390429); expected 358.6 (0.02)
Passed bias filter:                      518  (0.0288917); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.48
# Mc/sec: 3416.79
//
Query:       EEA21017.1  [L=477]
Description: dihydroorotate reductase PyrE, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.4e-65  221.4   0.1    1.8e-65  221.0   0.1    1.1  1  DHO_dh          Dihydroorotate dehydrogenase
      0.004   16.7   0.1        2.6    7.4   0.0    2.3  2  PcrB            PcrB family
  ------ inclusion threshold ------
      0.017   14.5   0.0      0.028   13.8   0.0    1.4  1  Ribul_P_3_epim  Ribulose-phosphate 3 epimerase family
      0.059   12.7   0.7      0.091   12.1   0.1    1.6  2  NMO             Nitronate monooxygenase
       0.14   11.5   1.2         10    5.5   0.0    2.5  2  LVIVD           LVIVD repeat


Domain annotation for each model (and alignments):
>> DHO_dh  Dihydroorotate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  221.0   0.1   5.2e-69   1.8e-65       2     293 ..     134     473 ..     133     474 .. 0.90

  Alignments for each domain:
  == domain 1  score: 221.0 bits;  conditional E-value: 5.2e-69
                 G-EEETTEEESSSEEE-TTSSTTSSSHHHHHCTTSSEEEEEEE-SS-B--S-S--EEEETTCTEEEE---S-BS-HHHHHHHHHHHHHHHHCC...... CS
      DHO_dh   2 latkvlglkfknpiglAaGfdkegeeilkllklgfgaieigsvtpkpqeGnpkPrvfrlkedrsvlNslGlnneGldavlekllkrrkeqeek...... 94 
                 l+t+v+g ++ npig++ G+dk++e  + l +lg++++e+g +tp pq Gnp+Prvfr++++  ++N++Gln++G+d++++ l++r++  +        
  EEA21017.1 134 LSTEVFGYTLSNPIGISGGLDKNAEIPDPLFALGAAVVEVGGTTPLPQDGNPRPRVFRIVSQSGMINRYGLNSKGADHMAKVLKQRVRDFAYAngfgys 232
                 899****************************************************************************9999999987655589**** PP

                 .......................CEEEEEEE-TTS.....S.HHHHHHHHHHHHGGGESEEEEES-SCTCCTSCCCGCHHHHHHHHHHHHHHHH..... CS
      DHO_dh  95 ......................kelginlskakkt.....enavddyvevvrkigpfadilelNvSsPntpglrdlqekeelkaillkvvkevs..... 161
                                       k l++ ++k+k t       + +dyv++v +i+p+adi+++NvSsPntpglr lq+   l++il  vv +++     
  EEA21017.1 233 dageervlngeagvppgslnqgKLLAVQVAKNKVTpesdiAAVTADYVYCVDRIAPYADIVVVNVSSPNTPGLRGLQATGPLTEILKGVVGAAKridrk 331
                 **********************99999999999998755555679*********************************************9999999** PP

                 .SSEEEEEE-SSSSHHHHHHHHHHHH.HHTECEEEE...BSEE-.....-CTTCCGCCCCTTSSEEEEEGGGHHHHHHHHHHHHHHTTT....S-EEEE CS
      DHO_dh 162 .kvpvlvKlaPdltdeekkdiadvll.elkldgiivtNttvqrl.....aidlkseknvkanktGGlsGkalkdialkvirelykrlkke...ipiIgv 250
                  k+ v+vK++Pd   ee+ d +  ++ e ++dg+iv+Ntt +r+     +  l  +++ +  +tGG sG++l ++ ++++ + +++l++      i ++
  EEA21017.1 332 tKPFVMVKVSPDEDSEEQVDGICHAVrESGVDGVIVGNTTNRRPgplpnRSPLTPKEKLTMTETGGYSGPQLFERTVELVSRYKQKLSDAespKTIFAS 430
                 99**********999999887777766***************982111123333344444449********************9998754222569*** PP

                 SS--SHHHHHHHHHHTECEEEESHHHHHHGTCHHHHHHHHHHH CS
      DHO_dh 251 GGiesgeDalekieaGAslvqvytalvfegpkiakkikkelee 293
                 GGi+ g+ a e + aGAs+  +yta+ f g   + ++k+el e
  EEA21017.1 431 GGITNGKQAQEVLDAGASVAMMYTAISFGGTGTVTRVKNELRE 473
                 ****************************************986 PP

>> PcrB  PcrB family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.9   0.0    0.0011       3.9       9      41 ..     337     372 ..     327     375 .. 0.73
   2 !    7.4   0.0   0.00073       2.6     167     207 ..     407     452 ..     397     468 .. 0.79

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0011
                 EEEE-TTSS...-CHHHHHHHHCTT-SEEEEECSTC CS
        PcrB   9 ltklDPeee...npdEiveiviesgtDavmigGsqs 41 
                 ++k+ P+e+   ++d i ++v esg D+v++g +++
  EEA21017.1 337 MVKVSPDEDseeQVDGICHAVRESGVDGVIVGNTTN 372
                 5688888761114566778889**********9875 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.00073
                 -HHHHHHHHHHHSSS....EEEEESS--SHHHHHHHHCC.SSEEEE CS
        PcrB 167 dveevialkkkleka....rlivGGGirsaEkAkevvea.ADvivv 207
                  ve+v + k+kl++a    +++  GGi ++ +A+ev+ a A v ++
  EEA21017.1 407 TVELVSRYKQKLSDAespkTIFASGGITNGKQAQEVLDAgASVAMM 452
                 56888888888887533338*****************998887665 PP

>> Ribul_P_3_epim  Ribulose-phosphate 3 epimerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   7.7e-06     0.028     132     197 ..     390     456 ..     329     457 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 7.7e-06
                     EEESS-TT-SS----CCHHHHHHHHHHHHHHHT---EEEEESS--T.TTCHHHHHHT--EEEESHHH CS
  Ribul_P_3_epim 132 llmsvePgfgGQkFipevlekikkvrklidekeldlkievDGGvkl.dnieqiaeagadvlVagsav 197
                     l m+   g +G +  + ++e +++ ++++++ e   +i++ GG+++ ++++++ +aga v  + +a+
      EEA21017.1 390 LTMTETGGYSGPQLFERTVELVSRYKQKLSDAESPKTIFASGGITNgKQAQEVLDAGASVAMMYTAI 456
                     679999**************************************764899********998877665 PP

>> NMO  Nitronate monooxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.1       1.1   3.8e+03     195     222 ..     146     174 ..     143     177 .. 0.78
   2 ?   12.1   0.1   2.5e-05     0.091     166     225 ..     394     456 ..     390     474 .. 0.78

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 1.1
         NMO 195 PviAaGGiidrrgv.aaaLalGAsgvqig 222
                 P+   GG+ ++ ++ +  +alGA+ v +g
  EEA21017.1 146 PIGISGGLDKNAEIpDPLFALGAAVVEVG 174
                 555678888888885678999**999998 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 2.5e-05
         NMO 166 eaGGhqGtpevgdkglfaLvpqvldavd.....iPviAaGGiidrrgvaaaLalGAsgvqigtrf 225
                 e GG+ G p+   + +++Lv + ++ ++       + A GGi ++++ + +L +GAs + + t+ 
  EEA21017.1 394 ETGGYSG-PQLF-ERTVELVSRYKQKLSdaespKTIFASGGITNGKQAQEVLDAGASVAMMYTAI 456
                 7899999.4332.45666666655555555546669************************99985 PP

>> LVIVD  LVIVD repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.0    0.0028        10       7      19 ..      69      81 ..      64      84 .. 0.85
   2 ?    4.3   0.3    0.0069        25       8      38 ..     274     307 ..     270     311 .. 0.78

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0028
       LVIVD  7 vavsGnYaYvAdq 19
                va+ G+Y+Yv d 
  EEA21017.1 69 VALFGGYLYVTDT 81
                999*******986 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.0069
       LVIVD   8 avsGnYaYvAdq...dngLvIvDISNpSsptlkg 38 
                 av  +Y+Y  d+     + v+v +S p  p l g
  EEA21017.1 274 AVTADYVYCVDRiapYADIVVVNVSSPNTPGLRG 307
                 577899998776333579*********9999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (477 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       399  (0.0222544); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.46
# Mc/sec: 3087.18
//
Query:       EEA21018.1  [L=291]
Description: triosephosphate isomerase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.6e-41  141.1   0.0    4.6e-41  140.8   0.0    1.2  1  TIM       Triosephosphate isomerase
  ------ inclusion threshold ------
      0.023   14.9   0.0      0.051   13.8   0.0    1.6  1  DUF1921   Domain of unknown function (DUF1921)


Domain annotation for each model (and alignments):
>> TIM  Triosephosphate isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.8   0.0   5.1e-45   4.6e-41       4     237 ..      24     277 ..      21     283 .. 0.83

  Alignments for each domain:
  == domain 1  score: 140.8 bits;  conditional E-value: 5.1e-45
                 EEE-TBTS-HHHHHHHHHH.HHHHCHG......CTSEEEEE--GGGHHHHHHHHT...............TSSECEEES--BSSSSBS-TT--BHHHHH CS
         TIM   4 agNwKmnktleeakellkk.lkaklke......ekvevviappflylekvkklle...............esklklgaqnvsaeksGafTGevsaemlk 80 
                 +   Km+ t + + ++l+  l+ + +       +k+ ++++p+fl++ +++++++                  + lg q+  +e+ Ga+TGevs   l+
  EEA21018.1  24 IISLKMYFTPSRTLQYLRDlLDPQNEIvlaknrSKLLLALIPDFLTIYPCAEIIRewestlpetkqgeavPPPFLLGGQDSFWEDFGAYTGEVSPLSLR 122
                 5667777766666666655333332223433456677889999999999999998888888877664333334459*********************** PP

                 HTT-SEEEES-HHHHHHST--HHHHHHHHHHHHHTT-EEEEEE---HHH.....HHTT.HHHHHHHHHHHHTTTS-CCCGGCEEEEE--GGGSSSS--- CS
         TIM  81 dlgvkyviiGHsErrqlfkEtdelvakKvkaalksglkpilCvGEtlee.....reagkteevvkeqlkeilkkldeealknvviAYePvWAiGtgkta 174
                 ++g+++v +GH+Err lf+Etde+  kK++a+ k+gl p++C+GE  +      +  g + + +++q++++l+ l  +  + v+ AYePvWAiG+ ++a
  EEA21018.1 123 EIGASLVELGHAERRDLFGETDEITGKKAAAVSKQGLIPLVCIGELSAPgqvasEAVGLAVRECETQIRAVLSALPGH--APVIFAYEPVWAIGKPQPA 219
                 *********************************************76543222255566788999**********998..79***************** PP

                 -HHHHHHHHHHHHHHHHHHSTHHHHTTSEEEEESS--TTTHHHHHTSTT--EEEESGGGCSHH CS
         TIM 175 tpeqaqevhaairkelaekvskevaekirilYGGsvnkenakellkqkdidGlLvGgaslkae 237
                   e++ +v+a ir ++ ++     + ++rilYGGs  +   +e    k +dG++ G+ ++++e
  EEA21018.1 220 GVEHVAAVVAGIRAVIGKR-----EGDVRILYGGSAGPGLWSEGGLGKAVDGMFLGRFAHQVE 277
                 ****************777.....789******************************999887 PP

>> DUF1921  Domain of unknown function (DUF1921)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   5.7e-06     0.051      24      48 ..     167     191 ..     152     193 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 5.7e-06
     DUF1921  24 nlssPgqvAsGafseAvntdnGriR 48 
                  ls PgqvAs a  +Av +   +iR
  EEA21018.1 167 ELSAPGQVASEAVGLAVRECETQIR 191
                 79*****************999999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (291 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       238  (0.0132746); expected 358.6 (0.02)
Passed bias filter:                      223  (0.0124379); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 2057.47
//
Query:       EEA21019.1  [L=160]
Description: ribose-5-phosphate isomerase B, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      1e-41  142.2   0.0    1.2e-41  142.0   0.0    1.0  1  LacAB_rpiB      Ribose/Galactose Isomerase
  ------ inclusion threshold ------
      0.073   13.1   0.1       0.14   12.2   0.0    1.6  1  Gly_rich_SFCGS  Glycine-rich SFCGS


Domain annotation for each model (and alignments):
>> LacAB_rpiB  Ribose/Galactose Isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  142.0   0.0   1.3e-45   1.2e-41       1     139 []      10     151 ..      10     151 .. 0.95

  Alignments for each domain:
  == domain 1  score: 142.0 bits;  conditional E-value: 1.3e-45
                 EEEEE-GCGHHHHHHHHHHHHHT..TTEEEEECESS.SS---HHHHHHHHHHHHHTTSSSEEEEEESSSHHHHHHHHTSTT--EEE-SSHHHHHHHHHT CS
  LacAB_rpiB   1 iaigsDhagfelkekikeyLkek..ghevidvgtes.eesvdYpdfakkvaeavasgeadlgiliCgtGiGmsiaaNkvkgiraalchdeesAklareh 96 
                 i+++ D+ag+++k +ik+ L+++    +v+dvg++s ++++ Yp+ a + a+++a+g+ad+g++iCgtG G++iaaNkv+gira+++hd++s+++a  +
  EEA21019.1  10 IVMAGDEAGYDYKAAIKDLLEKSplVESVVDVGATSlTDKTAYPHSAVEGAKLIAEGKADRGLFICGTGLGVAIAANKVPGIRAVTAHDPFSVERAILS 108
                 8899****************77433448*****999999************************************************************ PP

                 T--SEEEEETTTS-HHHHHHHHHHHHHS---.HTHHHHHHHHH CS
  LacAB_rpiB  97 nnanvlalGarvigeelakeivkaFletefeeggrharrvdki 139
                 n+a++l++G+rvig+elak++   +l+ +f++++ +a +v+ i
  EEA21019.1 109 NDAQILCFGQRVIGIELAKKLTLDWLNYRFDPKSGSAAKVQAI 151
                 ******************************9999999999876 PP

>> Gly_rich_SFCGS  Glycine-rich SFCGS
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   1.5e-05      0.14      41     108 ..      62     130 ..      25     135 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 1.5e-05
  Gly_rich_SFCGS  41 vmkkeeadlgisfcgsggagaltaqtkygyka..kyglrsveegvtaikegkkvlgfgf.ldkeelgkrlv 108
                     ++ + +ad g+ +cg+g   a+ a++  g +a   ++  sve  +  + + +++l fg  +   el k+l+
      EEA21019.1  62 LIAEGKADRGLFICGTGLGVAIAANKVPGIRAvtAHDPFSVERAI--LSNDAQILCFGQrVIGIELAKKLT 130
                     677889***********9999999999999862256677888776..678888899886233456777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (160 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       329  (0.0183502); expected 358.6 (0.02)
Passed bias filter:                      310  (0.0172904); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.24s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1162.92
//
Query:       EEA21020.1  [L=285]
Description: U-box domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.2e-21   75.3   0.0    5.8e-21   74.4   0.0    1.4  1  U-box          U-box domain
    2.7e-08   33.3   0.6    0.00069   19.5   0.0    4.3  3  TPR_2          Tetratricopeptide repeat
    2.6e-07   30.2   0.2    0.00015   21.4   0.0    3.7  4  TPR_1          Tetratricopeptide repeat
    3.1e-07   30.9   4.6      0.037   14.7   0.0    2.8  2  TPR_16         Tetratricopeptide repeat
    3.3e-05   23.5   0.0    0.00022   20.8   0.0    2.2  2  TPR_11         TPR repeat
    8.2e-05   23.3   4.4    0.00016   22.3   4.4    1.5  1  CHIP_TPR_N     CHIP N-terminal tetratricopeptide repeat domai
    0.00013   22.2   2.5       0.89    9.9   0.0    3.1  2  TPR_12         Tetratricopeptide repeat
    0.00032   21.3   4.7       0.32   11.9   0.0    3.5  3  TPR_14         Tetratricopeptide repeat
    0.00053   20.4   7.9     0.0065   17.0   0.0    3.1  4  TPR_19         Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.011   15.9   0.1       0.98    9.7   0.2    2.4  2  ANAPC3         Anaphase-promoting complex, cyclosome, subunit
      0.014   15.6   2.9      0.094   13.0   0.1    3.3  2  TPR_8          Tetratricopeptide repeat
      0.016   15.3   0.1      0.067   13.4   0.0    2.0  1  TPR_9          Tetratricopeptide repeat
      0.021   15.2   0.2        1.6    9.2   0.0    3.1  3  TPR_17         Tetratricopeptide repeat
      0.041   13.9   2.7        8.2    6.7   0.0    4.0  3  TPR_7          Tetratricopeptide repeat
      0.045   13.9   1.5      0.068   13.3   1.5    1.3  1  GlnD_UR_UTase  GlnD PII-uridylyltransferase
      0.052   13.6   0.9       0.13   12.2   0.9    1.7  1  GvpG           Gas vesicle protein G
      0.057   13.6   0.0       0.12   12.5   0.0    1.6  1  zf-NOSIP       Zinc-finger of nitric oxide synthase-interacti
      0.063   13.1   0.0       0.13   12.1   0.0    1.5  1  zf-Nse         Zinc-finger of the MIZ type in Nse subunit
      0.094   12.5   6.1       0.72    9.7   1.8    2.5  3  CdvA           CdvA-like coiled-coil domain
       0.11   12.8   2.0       0.21   12.0   2.0    1.5  1  HTH_WhiA       WhiA C-terminal HTH domain
        0.3   11.0   3.4        1.5    8.8   0.0    2.9  3  TPR_10         Tetratricopeptide repeat
       0.87    9.9   9.1       0.13   12.5   4.7    1.9  2  Phasin_2       Phasin protein


Domain annotation for each model (and alignments):
>> U-box  U-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.4   0.0   7.1e-24   5.8e-21       1      73 []     210     281 ..     210     281 .. 0.98

  Alignments for each domain:
  == domain 1  score: 74.4 bits;  conditional E-value: 7.1e-24
                 SSGGGB-TTT-SB-SSEEEETTTEEEEHHHHHHHHTT.SSB-TTT-SB--GGGSEE-HHHHHHHHHHHHHCTC CS
       U-box   1 iPdefldpitlelmkdPvilpsgvvvdrstiekhllsrdktdPftrepltqdqlipnlelKekIdefleekre 73 
                 +Pd+++d+it+e+m dPv++ sg+++dr  i+k+l++  ++dP+tr p+t ++l pn++lK++ +efl ++ +
  EEA21020.1 210 VPDFLIDNITFEVMHDPVVTVSGHSYDRLGITKYLEQ-ARVDPVTRVPMTVKDLRPNYSLKAACEEFLDKNGW 281
                 8************************************.******************************99865 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0   8.4e-07   0.00069       6      33 ..       7      34 ..       3      35 .. 0.93
   2 ?    2.7   0.0      0.21   1.7e+02       5      30 ..      40      65 ..      36      68 .. 0.88
   3 ?    5.5   0.3     0.026        22       6      22 ..      80      96 ..      77     109 .. 0.88

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 8.4e-07
       TPR_2  6 nlGlayyklgdyeeAleafekAleldPn 33
                + G+ ++k gdy+ A+e + +A++ +P+
  EEA21020.1  7 EKGNNLFKDGDYAGAEEMYSQAIQMNPK 34
                579************************7 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.21
       TPR_2  5 ynlGlayyklgdyeeAleafekAlel 30
                 n++   ++l +++ A+++ + A+ l
  EEA21020.1 40 TNRAVTRIRLEKWAGAEHDARIAIDL 65
                5899999***********99999887 PP

  == domain 3  score: 5.5 bits;  conditional E-value: 0.026
       TPR_2  6 nlGlayyklgdyeeAle 22
                +l++a+++l++++eA +
  EEA21020.1 80 YLAQALLELQRPQEAYD 96
                799999****9999965 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0   1.9e-07   0.00015       4      33 ..       5      34 ..       2      35 .. 0.93
   2 ?    1.0   0.0      0.54   4.4e+02       4      30 ..      39      65 ..      36      67 .. 0.87
   3 ?    2.8   0.0      0.14   1.2e+02       6      21 ..      80      95 ..      77      97 .. 0.90
   4 ?   -2.3   0.0       5.9   4.8e+03      20      28 ..      98     106 ..      98     107 .. 0.83

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 1.9e-07
                HHHHHHHHHHTT-HHHHHHHHHHHHHHSTT CS
       TPR_1  4 lynlGnayfklgkydeAleyyekALelnPn 33
                ++ +Gn +fk g+y  A+e y++A++ nP+
  EEA21020.1  5 FKEKGNNLFKDGDYAGAEEMYSQAIQMNPK 34
                6789*************************7 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.54
                HHHHHHHHHHTT-HHHHHHHHHHHHHH CS
       TPR_1  4 lynlGnayfklgkydeAleyyekALel 30
                + n++++  +l+k+  A+ + + A+ l
  EEA21020.1 39 FTNRAVTRIRLEKWAGAEHDARIAIDL 65
                689**************9998888876 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.14
                HHHHHHHHTT-HHHHH CS
       TPR_1  6 nlGnayfklgkydeAl 21
                 l++a+++l++++eA 
  EEA21020.1 80 YLAQALLELQRPQEAY 95
                69*************7 PP

  == domain 4  score: -2.3 bits;  conditional E-value: 5.9
                 HHHHHHHHH CS
       TPR_1  20 AleyyekAL 28 
                 A+++y+  L
  EEA21020.1  98 AIDAYRASL 106
                 99***9776 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   4.5e-05     0.037       3      32 ..       8      37 ..       7      45 .. 0.87
   2 !   12.7   5.4   0.00019      0.16       4      59 ..      43     101 ..      40     109 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 4.5e-05
      TPR_16  3 laraalragdyddAaaaleaalkrdpssPd 32
                +++ +++ gdy+ A++++ +a+ ++p++P 
  EEA21020.1  8 KGNNLFKDGDYAGAEEMYSQAIQMNPKEPS 37
                6899*********************87775 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 0.00019
      TPR_16   4 araalragdyddAaaaleaalkrdpssPd..aaeAllllgdaalrqgrlaeAa.alyra 59 
                 a  ++r+ +++ A++ +++a++++++s +     ++l+l++a+l+++r +eA   +++a
  EEA21020.1  43 AVTRIRLEKWAGAEHDARIAIDLHGGSKAaaSLKSSLYLAQALLELQRPQEAYdVAIDA 101
                 55678999*******************996666789**********9988884333333 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8   0.0   2.7e-07   0.00022       1      36 [.       9      44 ..       9      49 .. 0.94
   2 ?   -0.5   0.1       1.3   1.1e+03       9      20 ..      94     105 ..      91     107 .. 0.80

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 2.7e-07
      TPR_11  1 GdayyeqGkyeeAieaYkkAlkldPdnaeayynLGl 36
                G+ +++ G+y +A e Y++A++ +P+ ++++ n+++
  EEA21020.1  9 GNNLFKDGDYAGAEEMYSQAIQMNPKEPSFFTNRAV 44
                899******************************986 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 1.3
      TPR_11   9 kyeeAieaYkkA 20 
                  y+ Ai aY++ 
  EEA21020.1  94 AYDVAIDAYRAS 105
                 6899*****975 PP

>> CHIP_TPR_N  CHIP N-terminal tetratricopeptide repeat domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.3   4.4     2e-07   0.00016       1      74 [.     123     198 ..     123     208 .. 0.91

  Alignments for each domain:
  == domain 1  score: 22.3 bits;  conditional E-value: 2e-07
                 HHHCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCTTCCHGTTTSXCHH..HCHHHHHHHHHHHHHHHHHHHHHH CS
  CHIP_TPR_N   1 AkkkrfrkeEekRikqEieLqsyLnkLideDkerkleeleeeeekeedek..leeeeeeieeeaderlaeLnelFa 74 
                 Ak++++ ++E  R+++  e  + +++Li++D+e++l+el+++ ++ e  +   +e++++++eead++++++ + F+
  EEA21020.1 123 AKQQIWAAKETARLREMDESLASVESLIEADLEQQLNELKTQLNNGEIGEigFNEDQKALREEADKKIRHVRDAFK 198
                 9**************************************8887777777666899*****************9997 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.9   0.0    0.0011      0.89       9      31 ..       8      30 ..       2      34 .. 0.77
   2 !    8.4   2.7    0.0032       2.6       8      71 ..      41     101 ..      37     111 .. 0.89

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.0011
      TPR_12  9 laavlrrlgrydeAlellekale 31
                 ++ l++ g+y+ A+e++ +a++
  EEA21020.1  8 KGNNLFKDGDYAGAEEMYSQAIQ 30
                57778888888888888888876 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0032
      TPR_12   8 nlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleea 71 
                 n+a++  rl++++ A+   + a++++    G + ++ + +   L++++++l r++eA +   +a
  EEA21020.1  41 NRAVTRIRLEKWAGAEHDARIAIDLH---GGSKAAASLKSSLYLAQALLELQRPQEAYDVAIDA 101
                 8899999*******************...99************************996655555 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.9   0.0    0.0004      0.32      11      37 ..      12      38 ..       6      45 .. 0.85
   2 !    9.0   0.6    0.0034       2.8       5      30 ..      79     104 ..      76     114 .. 0.74
   3 ?   -1.7   0.1       9.4   7.6e+03      12      31 ..     134     153 ..     125     162 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.0004
      TPR_14 11 llalGdpdeAiallrralalaPddaea 37
                l+  Gd+++A++++ +a++ +P+++ +
  EEA21020.1 12 LFKDGDYAGAEEMYSQAIQMNPKEPSF 38
                6778******************99876 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.0034
      TPR_14   5 lalaeallalGdpdeAiallrralal 30 
                 l la+all+l++p+eA +++ +a ++
  EEA21020.1  79 LYLAQALLELQRPQEAYDVAIDAYRA 104
                 679*********99966666555443 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 9.4
      TPR_14  12 lalGdpdeAiallrralala 31 
                 ++l++ de++a  + +++++
  EEA21020.1 134 ARLREMDESLASVESLIEAD 153
                 46777788888888777765 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0   7.9e-06    0.0065       1      45 [.      12      56 ..      12      57 .. 0.87
   2 ?    6.9   0.8     0.011       9.1      25      44 ..      75      94 ..      62      98 .. 0.83
   3 ?    0.4   0.1       1.2   9.8e+02       4      25 ..      92     113 ..      92     133 .. 0.80
   4 ?   -2.3   0.4       8.1   6.6e+03      39      68 .]     137     165 ..     134     165 .. 0.77

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 7.9e-06
      TPR_19  1 llaegdyaeAlalleqalqedpknaearllLAeallalgqldeAe 45
                l+++gdya A ++++qa+q +pk +    + A   + l  ++ Ae
  EEA21020.1 12 LFKDGDYAGAEEMYSQAIQMNPKEPSFFTNRAVTRIRLEKWAGAE 56
                6899*******************9999988888888887777765 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.011
      TPR_19 25 aearllLAeallalgqldeA 44
                +   l+LA+all+l +++eA
  EEA21020.1 75 LKSSLYLAQALLELQRPQEA 94
                556789*************9 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 1.2
      TPR_19   4 egdyaeAlalleqalqedpkna 25 
                 ++ y+ A++++++ l++ + + 
  EEA21020.1  92 QEAYDVAIDAYRASLSAMNAQT 113
                 678999*****99988766554 PP

  == domain 4  score: -2.3 bits;  conditional E-value: 8.1
      TPR_19  39 gqldeAealLdalpeedpddaryasLlAkl 68 
                  + de  a ++ l e+d   +++  L+ +l
  EEA21020.1 137 REMDESLASVESLIEADLE-QQLNELKTQL 165
                 5778888888888888888.8888888876 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0      0.11        90      33      75 ..      12      55 ..       7      60 .. 0.89
   2 ?    9.7   0.2    0.0012      0.98      54      78 ..      73      97 ..      58     102 .. 0.69

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.11
                HHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHH CS
      ANAPC3 33 lylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeA 75
                l+++g+y  A e +++a + n+k +      A + + L+k+  A
  EEA21020.1 12 LFKDGDYAGAEEMYSQAiQMNPKEPSFFTNRAVTRIRLEKWAGA 55
                89***************999999999999999999999999776 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.0012
                C-HHHHHHHHHHHHHTT-HHHHHHH CS
      ANAPC3 54 kslgcrylfAqcllkLkkyeeAiaa 78
                 sl++ + +Aq+ll+L++ +eA+++
  EEA21020.1 73 ASLKSSLYLAQALLELQRPQEAYDV 97
                5566666677777777777777765 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.1   0.00012     0.094       7      33 ..       8      34 ..       7      35 .. 0.92
   2 ?    1.1   0.1      0.73   5.9e+02      14      26 ..      92     104 ..      76     108 .. 0.52

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 0.00012
                HHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8  7 lgsiylklgdyeeAkeyyekaleldpd 33
                +g+ ++k gdy  A+e y +a++++p+
  EEA21020.1  8 KGNNLFKDGDYAGAEEMYSQAIQMNPK 34
                67889999******************8 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.73
                 TT-HHHHHHHHHH CS
       TPR_8  14 lgdyeeAkeyyek 26 
                 ++ y+ A+ +y+ 
  EEA21020.1  92 QEAYDVAIDAYRA 104
                 3334555555555 PP

>> TPR_9  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   8.2e-05     0.067       9      70 ..      16      77 ..      12      80 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 8.2e-05
       TPR_9  9 edweralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalapdapdaeaira 70
                 d++ a +++   ++++P++p+    R++ + +l+ +++A  d   +++l +   +a+ +++
  EEA21020.1 16 GDYAGAEEMYSQAIQMNPKEPSFFTNRAVTRIRLEKWAGAEHDARIAIDLHGGSKAAASLKS 77
                58999999***********************************9999998888888877766 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       9.2   7.5e+03      22      34 .]      11      23 ..       7      23 .. 0.76
   2 ?    9.2   0.0     0.002       1.6       1      33 [.      24      56 ..      24      57 .. 0.89
   3 ?    2.3   0.1      0.33   2.6e+02      18      32 ..      80      94 ..      76      96 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 9.2
      TPR_17 22 lllknGdlmtArq 34
                 l k Gd++ A++
  EEA21020.1 11 NLFKDGDYAGAEE 23
                567899*999986 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.002
      TPR_17  1 lylkaleldPnnadaynnLAelllknGdlmtAr 33
                +y +a++ +P+ + +++n+A++  ++ +++ A+
  EEA21020.1 24 MYSQAIQMNPKEPSFFTNRAVTRIRLEKWAGAE 56
                5999******************99888887775 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.33
      TPR_17 18 nLAelllknGdlmtA 32
                +LA++ll++ ++++A
  EEA21020.1 80 YLAQALLELQRPQEA 94
                8**********9998 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   0.0      0.01       8.2      10      28 ..      13      31 ..       9      37 .. 0.78
   2 ?   -2.5   0.0       8.5   6.9e+03       4      18 ..      41      55 ..      39      56 .. 0.82
   3 ?    4.3   0.4     0.061        49       4      28 ..      80     109 ..      77     117 .. 0.66

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.01
       TPR_7 10 srlGdyeeAielyeqsLal 28
                +++Gdy+ A+e y q++++
  EEA21020.1 13 FKDGDYAGAEEMYSQAIQM 31
                689************5444 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 8.5
       TPR_7  4 nLarlysrlGdyeeA 18
                n a+++ rl +++ A
  EEA21020.1 41 NRAVTRIRLEKWAGA 55
                779999999999887 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.061
       TPR_7   4 nLarlysr....lGdyeeAielyeqsL.al 28 
                 +La++  +    +  y+ Ai+ y++sL a+
  EEA21020.1  80 YLAQALLElqrpQEAYDVAIDAYRASLsAM 109
                 677777774445556777777777777555 PP

>> GlnD_UR_UTase  GlnD PII-uridylyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   1.5   8.4e-05     0.068      55     144 ..     112     199 ..     101     201 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 8.4e-05
  GlnD_UR_UTase  55 erstlealeelvergllteeeakelreayrflrrlehrLqlladrqthrLpfdeeeqrrlaealgyredkaafmkelfqhaerVrrlfek 144
                    ++++l+++   +++++  ++e ++lre  + l ++e  + +  ++q ++L ++  +  ++   +g++ed++a+++e  ++ ++Vr  f++
     EEA21020.1 112 QTENLSKIVLRAKQQIWAAKETARLREMDESLASVESLIEADLEQQLNELKTQ-LNNGEI-GEIGFNEDQKALREEADKKIRHVRDAFKA 199
                    66788888888999***************************************.555555.568999******************99875 PP

>> GvpG  Gas vesicle protein G
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.9   0.00016      0.13      31      58 ..     152     179 ..     135     198 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00016
        GvpG  31 enlrkeLaaLqqeLdaGeIdeeeFdrrE 58 
                 ++l+++L +L+ +L++GeI e  F++  
  EEA21020.1 152 ADLEQQLNELKTQLNNGEIGEIGFNEDQ 179
                 689******************9998765 PP

>> zf-NOSIP  Zinc-finger of nitric oxide synthase-interacting protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   0.00015      0.12      36      71 ..     209     244 ..     187     248 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00015
    zf-NOSIP  36 avkdfdccslslqacrdpvltedgylyekeaileyi 71 
                  v df    ++++  +dpv+t  g+ y++  i +y+
  EEA21020.1 209 VVPDFLIDNITFEVMHDPVVTVSGHSYDRLGITKYL 244
                 67788888999999******************9996 PP

>> zf-Nse  Zinc-finger of the MIZ type in Nse subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   0.00016      0.13      14      46 ..     216     247 ..     210     264 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00016
                 -TTTSSB-SSEEEESSS--EEEHHHHHHHCTTT CS
      zf-Nse  14 CPltlqpfeePvtskkCpHvFEreaIlelikrk 46 
                 + +t++ +++Pv  +   H+++r  I++++++ 
  EEA21020.1 216 DNITFEVMHDPVV-TVSGHSYDRLGITKYLEQA 247
                 679*********8.5779************554 PP

>> CdvA  CdvA-like coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       9.6   7.8e+03      77      96 ..      15      34 ..      13      36 .. 0.72
   2 ?    4.4   0.1     0.039        32      77     108 ..      92     123 ..      89     135 .. 0.85
   3 ?    9.7   1.8   0.00088      0.72      44      96 ..     138     191 ..     129     201 .. 0.81

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 9.6
        CdvA 77 EeaYksaieairellesale 96
                + +Y  a e+++++++++ +
  EEA21020.1 15 DGDYAGAEEMYSQAIQMNPK 34
                66788888888888877655 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.039
        CdvA  77 EeaYksaieairellesaleekeeikkllekl 108
                  eaY+ ai+a+r +l  ++++ e+++k++ + 
  EEA21020.1  92 QEAYDVAIDAYRASLSAMNAQTENLSKIVLRA 123
                 689*********************99998765 PP

  == domain 3  score: 9.7 bits;  conditional E-value: 0.00088
        CdvA  44 klkkrlkeledqik.slekalanlkisyasGEidEeaYksaieairellesale 96 
                 +++++l+++e+ i+  le+ l  lk +   GEi E  +++ ++a+re+ ++  +
  EEA21020.1 138 EMDESLASVESLIEaDLEQQLNELKTQLNNGEIGEIGFNEDQKALREEADKKIR 191
                 67888888888775279*****************************99876554 PP

>> HTH_WhiA  WhiA C-terminal HTH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   2.0   0.00025      0.21       5      70 ..     109     172 ..     107     186 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00025
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHT-GGGS-HHHHHHHHHHHH-TTS-HHHHHHTT...T--H CS
    HTH_WhiA   5 vNcetaNlkKtvkaaakqieaielieekkgleklpeklkevaelRlenpdaSLkeLgell.eppisK 70 
                 +N +t Nl+K+v  a++qi a    +e+ +l++++e+l +v  l  +  +  L+eL   l + +i+ 
  EEA21020.1 109 MNAQTENLSKIVLRAKQQIWA---AKETARLREMDESLASVESLIEADLEQQLNELKTQLnNGEIGE 172
                 79**************99887...678888999***********************99996666665 PP

>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   0.0    0.0018       1.5       9      31 ..       9      31 ..       8      32 .. 0.92
   2 ?   -2.3   0.0       5.7   4.6e+03      14      26 ..      48      60 ..      40      66 .. 0.69
   3 ?    1.6   0.3      0.34   2.8e+02       8      21 ..      81      94 ..      79     109 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0018
      TPR_10  9 analrqrgrydeAealleealai 31
                +n l++ g+y++Ae+++ +a+++
  EEA21020.1  9 GNNLFKDGDYAGAEEMYSQAIQM 31
                788999***************97 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 5.7
      TPR_10 14 qrgrydeAealle 26
                ++ ++++Ae +++
  EEA21020.1 48 RLEKWAGAEHDAR 60
                6778999999877 PP

  == domain 3  score: 1.6 bits;  conditional E-value: 0.34
      TPR_10  8 LanalrqrgrydeA 21
                La al +++r +eA
  EEA21020.1 81 LAQALLELQRPQEA 94
                9999********99 PP

>> Phasin_2  Phasin protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   4.7   0.00016      0.13      37      94 ..      72     129 ..      69     134 .. 0.93
   2 ?   -2.3   0.1       6.8   5.6e+03      40      62 ..     139     161 ..     137     166 .. 0.62

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00016
    Phasin_2  37 rasleeslaaakallsakdpqellelqselaqpalekavayarklaelaaktqeeaak 94 
                  asl  sl  a+all+ + pqe++++  +  +++l ++ a++ +l+ ++ ++++++ +
  EEA21020.1  72 AASLKSSLYLAQALLELQRPQEAYDVAIDAYRASLSAMNAQTENLSKIVLRAKQQIWA 129
                 5789999999*******************************************99876 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 6.8
    Phasin_2  40 leeslaaakallsakdpqellel 62 
                 ++esla +++l++a   q+l el
  EEA21020.1 139 MDESLASVESLIEADLEQQLNEL 161
                 56777777777777544444455 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (285 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       996  (0.0555525); expected 358.6 (0.02)
Passed bias filter:                      544  (0.0303419); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                        22  (0.00122706); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              22  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 2011.33
//
Query:       EEA21021.1  [L=381]
Description: alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.5e-20   71.9   1.6    5.9e-20   71.2   1.6    1.4  1  ADH_N         Alcohol dehydrogenase GroES-like domain
      2e-19   69.8   0.0    4.6e-19   68.7   0.0    1.6  2  ADH_zinc_N    Zinc-binding dehydrogenase
    1.7e-08   35.6   0.0    3.4e-08   34.6   0.0    1.5  1  ADH_zinc_N_2  Zinc-binding dehydrogenase
    1.9e-07   30.8   0.0    3.3e-07   30.0   0.0    1.4  1  Glu_dehyd_C   Glucose dehydrogenase C-terminus
  ------ inclusion threshold ------
      0.098   12.8   0.0       0.22   11.7   0.0    1.6  1  OapA          Opacity-associated protein A LysM-like domain


Domain annotation for each model (and alignments):
>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.2   1.6   1.6e-23   5.9e-20       2      82 ..      29     129 ..      28     160 .. 0.77

  Alignments for each domain:
  == domain 1  score: 71.2 bits;  conditional E-value: 1.6e-23
                 TEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS..--TT-EEEE-SEEE-SSSHHHHTT-GGG-................. CS
       ADH_N   2 gevlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkk..lkvGdrVvvepliscgeCaaCkegeenlC................. 81 
                  evl+++k++g+C++D+ + +g   +  ++p +lGHE vG+v+++g+ev++  l+ Gd V++  + +c +C+aC ++++  C                 
  EEA21021.1  29 SEVLVEIKYTGLCHTDIVVQEG-GMPIGHFPAVLGHEGVGIVKQIGSEVQDksLQPGDTVIL-SFHTCRKCKACLNDQHGSCsrctetnflhtaradgs 125
                 79*******************9.69999*********************9999*********.5568*********99998877765555555555555 PP

                 ...T CS
       ADH_N  82 ...e 82 
                    +
  EEA21021.1 126 spiS 129
                 5440 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.7   0.0   1.3e-22   4.6e-19       1     116 [.     206     326 ..     206     342 .. 0.90
   2 ?   -3.3   0.0       2.4   8.4e+03      45      63 ..     358     376 ..     353     378 .. 0.79

  Alignments for each domain:
  == domain 1  score: 68.7 bits;  conditional E-value: 1.3e-22
                 HHHHHHHHHHHHTT-.EEEEEESSHHHHHHHHHTTESEEEET....TTCHHHHHHHHHTTTSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSC..TS CS
  ADH_zinc_N   1 gvGlaavqlAkalGa.eviavdsseeklelakklGadeviny....keadlverikeltggegvdvvfecvGsgatleaalkllkpgGrlvvvGg..gk 92 
                 +vG a++ +Aka+G+ + ia+d+ ++kle+a++l   +++n+       +l+e+i ++  +egvd++++++G +++l++a+k+l++gG+l++vG+  ++
  EEA21021.1 206 PVGFAGLLAAKAIGVkNLIAIDIVDSKLEIAASLTGSHTVNSlkppGG-SLSEKILAIY-PEGVDYIMDTSGRPQVLQDAVKALAHGGTLALVGVppPT 302
                 79*******************************988******986644.7*********.9***********************************888 PP

                 SEEEEEHHHHHHTT-EEEEE-SSC CS
  ADH_zinc_N  93 geeefdlrnlllkeksilGsllgs 116
                 g  e+++ +ll   k+i+G++ g 
  EEA21021.1 303 GTIEVNALDLLVSCKRIVGVIEGA 326
                 8888****************9987 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 2.4
                 HHHHHHHHHTTTSSEEEEE CS
  ADH_zinc_N  45 dlverikeltggegvdvvf 63 
                 +l+++i++l  g  v+vv+
  EEA21021.1 358 QLDKAIEDLKSGTVVKVVL 376
                 6889999999998999987 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.6   0.0   9.3e-12   3.4e-08      20     132 ..     264     375 ..     242     376 .. 0.88

  Alignments for each domain:
  == domain 1  score: 34.6 bits;  conditional E-value: 9.3e-12
                   TT-EEEEEES-HHHHH.HHHHHHEEEEEEEEE----.S-EEE-CHHHCTTT-EEEE--GGG...-.-HHHHHHHHHHHHHHH----.EEEEEEGGGH CS
  ADH_zinc_N_2  20 gegvDvvldtvggealleaslkvlpggGrlvsiggpplsaallkpakkrkgrsvkyeflfsmkasaqadileelaalieeGklrpv.vdrvfpleea 115
                   +egvD++ dt g ++ l++++k+l++gG+l  +g pp + ++  +a++      +++ +++  a+ +++il +l +l+ eGk+ ++ +++ +p +++
    EEA21021.1 264 PEGVDYIMDTSGRPQVLQDAVKALAHGGTLALVGVPPPTGTIEVNALDLLVSCKRIVGVIEGAAN-PKKILPHLINLFNEGKFPVReLTKIYPANQL 359
                   799*********99999*******999***99998888888888888888888889999987787.****************987624567****** PP

                   HHHHHHHHSS--SSEEE CS
  ADH_zinc_N_2 116 aeAhrylesgrarGKiV 132
                    +A+++l+sg ++ K+V
    EEA21021.1 360 DKAIEDLKSGTVV-KVV 375
                   **********876.555 PP

>> Glu_dehyd_C  Glucose dehydrogenase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.0   0.0   9.1e-11   3.3e-07      32     209 ..     197     375 ..     183     378 .. 0.64

  Alignments for each domain:
  == domain 1  score: 30.0 bits;  conditional E-value: 9.1e-11
  Glu_dehyd_C  32 esalvlGaGslGLLalalleaeerglervyvlgrrdrpdptidlveel.GatYvdsretpvdeipe....as.eemdlvvEaTGsakhafeaiealap 123
                  +++ ++G G++G+    ll+a+  g++++  +   d  d ++++ ++l G+  v+s + p  +++e    ++ e +d+++++ G ++++ +a++ala 
   EEA21021.1 197 SKVAIIGMGPVGFAG--LLAAKAIGVKNLIAI---DIVDSKLEIAASLtGSHTVNSLKPPGGSLSEkilaIYpEGVDYIMDTSGRPQVLQDAVKALAH 289
                  467899*****9877..455444555544444...5677899999998455567777766544443111143378*********************** PP

  Glu_dehyd_C 124 nGvaaLlGvpeds.evevdggelhrelvleNkalvGsvNanrrhfeaavdtLaal..peslldelvtkvvdldeleeAfeddd..etiKtv 209
                   G  aL+Gvp ++ ++ev++ +    l+++ k +vG +   ++  +  + +L +l  + ++  + +tk ++ ++l++A ed +  + +K+v
   EEA21021.1 290 GGTLALVGVPPPTgTIEVNALD----LLVSCKRIVGVIEGAANPKK-ILPHLINLfnEGKFPVRELTKIYPANQLDKAIEDLKsgTVVKVV 375
                  **********987577777654....55667788887765444322.23333222112344444457777777777777643322555655 PP

>> OapA  Opacity-associated protein A LysM-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   6.1e-05      0.22      13      56 ..     336     379 ..     334     381 .] 0.93

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 6.1e-05
        OapA  13 LaqvFRdnnLplsdvnalakveGadkplSnlksGqkvriklnaq 56 
                 L ++F + + p+ ++ ++  ++  dk++ +lksG  v++ l+ +
  EEA21021.1 336 LINLFNEGKFPVRELTKIYPANQLDKAIEDLKSGTVVKVVLSWE 379
                 899***********************************988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (381 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       600  (0.0334653); expected 358.6 (0.02)
Passed bias filter:                      462  (0.0257683); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2636.71
//
Query:       EEA21022.1  [L=91]
Description: Acyl CoA binding protein family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-22   79.5   3.3    1.8e-22   79.3   3.3    1.0  1  ACBP      Acyl CoA binding protein
  ------ inclusion threshold ------
      0.013   15.9   0.3       0.13   12.7   0.1    1.9  2  FERM_M    FERM central domain


Domain annotation for each model (and alignments):
>> ACBP  Acyl CoA binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.3   3.3     2e-26   1.8e-22       1      84 [.       4      83 ..       4      84 .. 0.92

  Alignments for each domain:
  == domain 1  score: 79.3 bits;  conditional E-value: 2e-26
                HHHHHHHHHHH.H...HSTS---HHHHHHHHHHHHHHHTSS--S-.---TTSHHHHHHHHHHHHTTT--HHHHHHHHHHHHHHHH CS
        ACBP  1 eeeFekavaavkklekklkkkpsneeklelYglyKqateGdvnts.rPsaldfkgkaKwdaWkalkglskeeAkkkYiellkelv 84
                +e+Fe+a+ +vkk    l +k +n+ekle+Ygl+Kqa+   ++ + +Psa+ f++k K++aW+++++ls eeA+++Yiel+++l+
  EEA21022.1  4 QERFEQATIDVKK----L-NKCDNSEKLEFYGLFKQAKGETFDPKsKPSAFAFEAKYKHQAWEKVSHLSVEEAQEQYIELFEKLK 83
                689********65....2.4589***************99997766************************************986 PP

>> FERM_M  FERM central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.0     0.041   3.7e+02      15      52 ..       7      43 ..       1      55 [. 0.70
   2 ?   12.7   0.1   1.4e-05      0.13      86     115 ..      58      88 ..      56      89 .. 0.90

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.041
                HHHHHHHHHTTSSXXXHHHHHHHHHHHHHHHHHHHHCX CS
                xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      FERM_M 15 YeQakwdllegeldcteeeallLAaLqlqiekgdlses 52
                +eQa  d+ +   +c+ +e l++ +L  q++  +++++
  EEA21022.1  7 FEQATIDVKK-LNKCDNSEKLEFYGLFKQAKGETFDPK 43
                6777777655.446888888888888888888877743 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 1.4e-05
                 HHHHHHHHHHHHHHHHHHHHHHHTST.TTTX CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxx.xxxx RF
      FERM_M  86 eahqnvaqlslaeaklkylqawqslp.dyGv 115
                 +a+++v++ls +ea+ +y+++ ++l+  yG+
  EEA21022.1  58 QAWEKVSHLSVEEAQEQYIELFEKLKaKYGL 88 
                 699*********************9867776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (91 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       860  (0.047967); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.45
# Mc/sec: 612.73
//
Query:       EEA21023.1  [L=91]
Description: Acyl CoA binding protein family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-22   79.5   3.3    1.8e-22   79.3   3.3    1.0  1  ACBP      Acyl CoA binding protein
  ------ inclusion threshold ------
      0.013   15.9   0.3       0.13   12.7   0.1    1.9  2  FERM_M    FERM central domain


Domain annotation for each model (and alignments):
>> ACBP  Acyl CoA binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.3   3.3     2e-26   1.8e-22       1      84 [.       4      83 ..       4      84 .. 0.92

  Alignments for each domain:
  == domain 1  score: 79.3 bits;  conditional E-value: 2e-26
                HHHHHHHHHHH.H...HSTS---HHHHHHHHHHHHHHHTSS--S-.---TTSHHHHHHHHHHHHTTT--HHHHHHHHHHHHHHHH CS
        ACBP  1 eeeFekavaavkklekklkkkpsneeklelYglyKqateGdvnts.rPsaldfkgkaKwdaWkalkglskeeAkkkYiellkelv 84
                +e+Fe+a+ +vkk    l +k +n+ekle+Ygl+Kqa+   ++ + +Psa+ f++k K++aW+++++ls eeA+++Yiel+++l+
  EEA21023.1  4 QERFEQATIDVKK----L-NKCDNSEKLEFYGLFKQAKGETFDPKsKPSAFAFEAKYKHQAWEKVSHLSVEEAQEQYIELFEKLK 83
                689********65....2.4589***************99997766************************************986 PP

>> FERM_M  FERM central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.0     0.041   3.7e+02      15      52 ..       7      43 ..       1      55 [. 0.70
   2 ?   12.7   0.1   1.4e-05      0.13      86     115 ..      58      88 ..      56      89 .. 0.90

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.041
                HHHHHHHHHTTSSXXXHHHHHHHHHHHHHHHHHHHHCX CS
                xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      FERM_M 15 YeQakwdllegeldcteeeallLAaLqlqiekgdlses 52
                +eQa  d+ +   +c+ +e l++ +L  q++  +++++
  EEA21023.1  7 FEQATIDVKK-LNKCDNSEKLEFYGLFKQAKGETFDPK 43
                6777777655.446888888888888888888877743 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 1.4e-05
                 HHHHHHHHHHHHHHHHHHHHHHHTST.TTTX CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxx.xxxx RF
      FERM_M  86 eahqnvaqlslaeaklkylqawqslp.dyGv 115
                 +a+++v++ls +ea+ +y+++ ++l+  yG+
  EEA21023.1  58 QAWEKVSHLSVEEAQEQYIELFEKLKaKYGL 88 
                 699*********************9867776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (91 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       860  (0.047967); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.39u 0.25s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 672.31
//
Query:       EEA21024.1  [L=587]
Description: tyrosyl-DNA phosphodiesterase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   8.2e-170  565.3   0.0   9.5e-170  565.1   0.0    1.0  1  Tyr-DNA_phospho  Tyrosyl-DNA phosphodiesterase
    0.00027   20.9   0.1       0.16   11.9   0.0    2.3  2  PLDc_2           PLD-like domain
  ------ inclusion threshold ------
      0.021   14.4   0.7      0.058   13.0   0.3    1.9  2  DUF2271          Predicted periplasmic protein (DUF2271)


Domain annotation for each model (and alignments):
>> Tyr-DNA_phospho  Tyrosyl-DNA phosphodiesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  565.1   0.0  1.6e-173  9.5e-170       1     424 []      90     563 ..      90     563 .. 0.95

  Alignments for each domain:
  == domain 1  score: 565.1 bits;  conditional E-value: 1.6e-173
                      EEE--TTTT----------EE-HHHHH--TTEEEEEEE-S-EEHHHHHTTS.-T-...-EEEEEE..............ETTSEE-TEEEEEE- CS
  Tyr-DNA_phospho   1 plkltkirdlpeesernkdtitlkdilgdplleeavqfnFlfdlefllsqldedvrrkvkvvivhgakkeedeererleekakrypnvelieak 94 
                      p++lt+irdlp+++  n dt++l+dilgdp+++e++qfn++fd++f++sq+d+dvr++v+v+ivhg++k+++++r+r++e+++rypnve i a+
       EEA21024.1  90 PIQLTHIRDLPNDK--NIDTVQLHDILGDPMIRECWQFNYCFDVDFVMSQFDQDVRDLVQVKIVHGSWKQDSANRIRIDEACARYPNVESIVAY 181
                      699********655..99**************************************************************************** PP

                      --.TT--B---EEEEEETTSEEEEEEESS-BSHHHHHSSB-EEEE---EEE............S--SS--HHHHHHHHHHHTT..-HHHHTHHH CS
  Tyr-DNA_phospho  95 mpepfgthHsKmmilfyeddslrvvihtaNlieaDwgnmtqgvwrspllpl.....le.sskeseeesgtrFkrdLleYLkaygkkklkkliek 182
                      mpepfgthHsKmmil+++dd+++v+ihtaN+++ Dw+nm+q+vwrspll+l     ++ ++++++ ++g+rFkrdLl+YL+ yg+kk+++l+++
       EEA21024.1 182 MPEPFGTHHSKMMILLRHDDHAQVIIHTANMLAGDWTNMSQAVWRSPLLSLspirdNSeTAQAASFGTGARFKRDLLAYLEFYGNKKTRSLVDQ 275
                      ***************************************************9999966699999****************************** PP

                      HHTEE-GGGT-EEEEE---TTS--..........HHHHHHHHHHHTCT..T----EEEEEEE-SBB---S-.SSS---HHHHTHHHHHTTSS-- CS
  Tyr-DNA_phospho 183 lkkyDfsevrvaliaSvPgrhkgs......ktkwGlakLkkalkelplekeekskeleivaqvSSigslgstekwlknefleslspalqgkdks 270
                      l+k+Df+++r+aliaSvP+++++s      +t wG+++Lk++l+++pl  +ek++  ++v+q+SSi+slg+t+kwlk+++++sl+  +      
       EEA21024.1 276 LRKFDFQAIRAALIASVPSKERISradssrSTLWGWPALKDTLRQVPLRIREKNQCPHVVIQISSIASLGQTDKWLKDVLFDSLCLPS------ 363
                      ******************************9*****************999999999****************************999...... PP

                      -.HHHHHTEEEE..EE--BSGGGTTSTTGGGGGGG-B---...SGGHHHHHHHTS--EEEE-TT.....................TTTTT--B- CS
  Tyr-DNA_phospho 271 k.eeeekkskpkfkiifPtveevrrsldgyasggsihfkiqsaqqqkqleelkpylckwkqdse...................eeagRkraapH 344
                      +  +++k ++pk++iifPt++e+rrsl+gy sggsih+k+qs +qqkql++++pylc+w++d++                   ++agR+raapH
       EEA21024.1 364 ElPHTNKMPRPKYSIIFPTPDEIRRSLNGYGSGGSIHMKLQSITQQKQLQYMRPYLCQWAGDQKqtamgtlhlnaesvynsqrTDAGRRRAAPH 457
                      2222377899****************************************************99*******************99********* PP

                      -EEEEEE.--STTSEESEEEEES--BSHHHH--S.....SS--SSBEEEEEEEGG...............................------SE CS
  Tyr-DNA_phospho 345 iKtyirf.ssktlkkidWalltSaNLSkqAWGelekakeelrirsyElGVlvlpk.....................kdlpee....eektevgv 412
                      iKtyirf ++ ++++idWa++tSaNLS+qAWG+++++++e+ri+s+E+GVl++p+                     kd+p++    + +  vg+
       EEA21024.1 458 IKTYIRFaDKTKMDTIDWAMITSANLSTQAWGAAANSNGEVRICSWEIGVLFWPEliagdpfnpnstrtemvpsfrKDTPDPteseDVSSIVGF 551
                      *******9888999*****************************************9999999998888777777764444447777888999** PP

                      EESS-SSEEE-- CS
  Tyr-DNA_phospho 413 rvPydlplepYs 424
                      r+Pydlpl+pYs
       EEA21024.1 552 RMPYDLPLTPYS 563
                      ***********6 PP

>> PLDc_2  PLD-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.6   0.0    0.0012       6.9      17     100 ..     127     211 ..     120     222 .. 0.72
   2 !   11.9   0.0   2.6e-05      0.16      80     111 ..     454     497 ..     402     506 .. 0.71

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.0012
      PLDc_2  17 yyfvsdreildallkaakrgvkvrilldskkddagavdeaslkelkellleagvevrvfetllgslHaKlyli.dgk....tvivGSsN 100
                 y f   + ++ ++ ++ +  v+v+i+ +s+k+ ++a++ +    +++++  + +  ++ e+ +g+ H+K+++  + +     vi+ ++N
  EEA21024.1 127 YCF-DVDFVMSQFDQDVRDLVQVKIVHGSWKQ-DSANRIRIDEACARYPNVESIVAYMPEP-FGTHHSKMMILlR-HddhaQVIIHTAN 211
                 566.5556677777788888*********875.5778889999999998888888777655.4778*****9842.2223455555555 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 2.6e-05
      PLDc_2  80 gslHaKlyli.dgk.......tvivGSsNltkrgl....dlnlE 111
                    H K+y+   +k       +++++S+Nl+++++    ++n E
  EEA21024.1 454 AAPHIKTYIRfADKtkmdtidWAMITSANLSTQAWgaaaNSNGE 497
                 445999998754445788888**************664444444 PP

>> DUF2271  Predicted periplasmic protein (DUF2271)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0      0.91   5.4e+03      36      49 ..     341     354 ..     336     355 .. 0.79
   2 ?   13.0   0.3   9.7e-06     0.058       8      65 ..     406     474 ..     400     491 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 0.91
     DUF2271  36 Lavwgegekwlkdl 49 
                 +a +g+ +kwlkd+
  EEA21024.1 341 IASLGQTDKWLKDV 354
                 6667999*****95 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 9.7e-06
     DUF2271   8 ipqlkvaeyhrpYvavwledakgkyvktLavw...........gegekwlkdlrqWwrksgrklkeeid 65 
                 i q k+ +y rpY+  w  d+k+++  tL +              + +  ++++++ r++ +++ + id
  EEA21024.1 406 ITQQKQLQYMRPYLCQWAGDQKQTAMGTLHLNaesvynsqrtdAGRRRAAPHIKTYIRFADKTKMDTID 474
                 66999**************************999****99998888899999******99965545444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (587 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       348  (0.0194099); expected 358.6 (0.02)
Passed bias filter:                      279  (0.0155614); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.31s 00:00:00.90 Elapsed: 00:00:00.49
# Mc/sec: 3572.94
//
Query:       EEA21025.1  [L=891]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.3e-09   36.5   0.2    1.5e-08   34.7   0.0    2.0  2  NACHT         NACHT domain
    1.8e-08   35.0   0.0      3e-07   31.0   0.0    2.6  3  AAA_16        AAA ATPase domain
    1.3e-05   25.5   0.0    4.5e-05   23.7   0.0    1.9  1  AAA_22        AAA domain
    0.00023   21.5   0.1     0.0053   17.1   0.0    2.7  3  RNA_helicase  RNA helicase
     0.0026   17.1   0.2       0.57    9.4   0.1    2.7  2  KAP_NTPase    KAP family P-loop domain
  ------ inclusion threshold ------
      0.022   14.0   0.0      0.044   13.0   0.0    1.4  1  NB-ARC        NB-ARC domain
      0.029   15.0   0.0      0.094   13.3   0.0    1.9  1  Ank_2         Ankyrin repeats (3 copies)
      0.042   13.1   0.0      0.095   11.9   0.0    1.5  1  DUF2075       Uncharacterized conserved protein (DUF2075)
      0.047   13.6   0.0        0.1   12.5   0.0    1.6  1  ATPase_2      ATPase domain predominantly from Archaea
      0.051   13.9   0.0       0.78   10.1   0.0    2.6  1  Ank_5         Ankyrin repeats (many copies)
      0.088   13.2   0.0       0.33   11.4   0.0    2.1  1  AAA           ATPase family associated with various cellular 
       0.13   12.7   0.0       0.33   11.4   0.0    1.7  1  Goodbye       fungal STAND N-terminal Goodbye domain


Domain annotation for each model (and alignments):
>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.7   0.0     1e-11   1.5e-08       3     153 ..     320     484 ..     318     494 .. 0.79
   2 ?   -2.5   0.1       2.8   4.2e+03      57      88 ..     684     715 ..     672     718 .. 0.77

  Alignments for each domain:
  == domain 1  score: 34.7 bits;  conditional E-value: 1e-11
                 EEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-....-HCHHHCCCCTS--SSS-C.......................CHHHHC CS
       NACHT   3 vilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgna.rsladllfsqlpepaapvse.......................vwavll 77 
                 +++ G+aG GK++L+  +++   ++  ++++  + ++   +e+++   +  ++  +l +ql+++ ++ +                        ++++ +
  EEA21025.1 320 LWIYGAAGTGKSVLASMVIDHFSQDSNQKDH-AVAYVYIKGEDTTLRGSpSRIVSMLIKQLCWKLETLPSqtldyyrqckkdarlpvlnkletMFIECA 417
                 89**********************9988875.5555555555544444437899999999999888888789*****************9999999999 PP

                 CSCCCEEEEEE-STT-SS-TCH.........HHHHHCTTTTT--EEEEEEECCCHHHHCTTSSCE..EEEE--TCC CS
       NACHT  78 elperlLlilDglDelvtdlgqkekqpvrtlLselirkkllpeasllltvrpralrdleeqleeaivlevegfses 153
                     r++ i+DglDe++++ ++    p+ + +   i ++  + +++l+t++   + d+e+ ++++++l +++++ +
  EEA21025.1 418 GSLSRVVAIIDGLDECEEKSRK----PILDFI---IAASQQTDCKFLVTSQW-EW-DIERAFRRTKSLIIPDMTSD 484
                 9999999**********95555....444444...77766677777766654.44.59999999988888888765 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 2.8
                 HHCCCCTS--SSS-CCHHHHCCSCCCEEEEEE CS
       NACHT  57 llfsqlpepaapvsevwavllelperlLlilD 88 
                 +++  lp  +++ ++ +  l+++pe +L ilD
  EEA21025.1 684 FMRNILPYCGSHFDTHIRRLTTIPEEILQILD 715
                 55555666667777777779********9999 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0         6     9e+03     102     132 ..     163     193 ..     131     200 .. 0.58
   2 !   31.0   0.0     2e-10     3e-07      14     164 ..     306     451 ..     304     458 .. 0.74
   3 ?    0.4   0.0      0.51   7.6e+02      47      97 ..     515     556 ..     507     669 .. 0.77

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 6
      AAA_16 102 eealaavpelagaeasrllellkrllallsr 132
                 ++ +++ ++ +++++  l +l +++la++++
  EEA21025.1 163 LDLFTQNNANSPELHDTLVALYTNILAFCRH 193
                 3333355555566666666666666666666 PP

  == domain 2  score: 31.0 bits;  conditional E-value: 2e-10
      AAA_16  14 salervrsgrp.elvllsGesGvGKsslvrellralekd......ggiflrgkcdql.esaipysalaqalareellrqlldeaesaeleawrekleea 104
                 s++e++ s ++ + + ++G++G+GKs l+ ++ +++++d       + +++ k ++   ++ p s ++++l + +l+ +l++ +++  l+++r+ +++ 
  EEA21025.1 306 SVYEKWVSEQCtGPLWIYGAAGTGKSVLASMVIDHFSQDsnqkdhAVAYVYIKGEDTtLRGSP-SRIVSMLIK-QLCWKLETLPSQ-TLDYYRQ-CKKD 400
                 56777777777799************************9999984244466666666224444.668888877.999999998666.4444444.4444 PP

      AAA_16 105 laavpelagaeasrllellkrll.allsrderplvlvlDdlqwadeaslql.laaLlrlles 164
                 ++            +l++l  ++ + + + +r +v ++D l+  +e s++  l+++ +++++
  EEA21025.1 401 AR----------LPVLNKLETMFiECAGSLSR-VVAIIDGLDECEEKSRKPiLDFIIAASQQ 451
                 44..........56777777777677777666.****************9999999988887 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.51
      AAA_16  47 alekdggiflrgkcdqlesaipysalaqalareellrqlldeaesaeleaw 97 
                  +ek+ggifl+ +++ +        laq++ + + +++ l+ + s++++ +
  EEA21025.1 515 LVEKSGGIFLWIDFQLN-------DLAQVI-E-HDVKAQLSVLPSDLQATY 556
                 34556899999999999.......789999.5.777777666555444444 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.7   0.0     3e-08   4.5e-05       8     127 ..     320     458 ..     315     464 .. 0.83

  Alignments for each domain:
  == domain 1  score: 23.7 bits;  conditional E-value: 3e-08
      AAA_22   8 lvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsst...sskdllrellralglelka........erlsseellealeqalrarav.... 91 
                 l ++G +GtGK++l+ ++ + + ++++++++ + +v+++    t   s++ + ++l ++l  +l++        +r+ +++ +  + + l++ +     
  EEA21025.1 320 LWIYGAAGTGKSVLASMVIDHFSQDSNQKDHAVAYVYIKGEDTTlrgSPSRIVSMLIKQLCWKLETlpsqtldyYRQCKKDARLPVLNKLETMFIecag 418
                 779*********************99999999999999999999999*************999999888888887777777766666666666668888 PP

      AAA_22  92 ...ielliiDEaqhlr..s.eealeeLrsllnlsrkgvqliL 127
                    +++ iiD  +     s + +l ++   +   ++++++++
  EEA21025.1 419 slsRVVAIIDGLDECEekSrKPILDFIIAASQ--QTDCKFLV 458
                 99999999999999966525888888877777..88888875 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0      0.44   6.6e+02      20      49 ..     251     280 ..     242     290 .. 0.76
   2 !   17.1   0.0   3.6e-06    0.0053       1      36 [.     320     355 ..     320     366 .. 0.81
   3 ?   -2.6   0.0       4.9   7.4e+03      51      64 ..     423     436 ..     362     456 .. 0.51

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.44
  RNA_helicase  20 kallkklklkkkdsvysrnpeddfwdgYtg 49 
                   +al+ + ++kk++s y++n +++f+dg  g
    EEA21025.1 251 TALAIREESKKTSSSYAQNERKEFLDGICG 280
                   4455445778999*************9865 PP

  == domain 2  score: 17.1 bits;  conditional E-value: 3.6e-06
  RNA_helicase   1 iwlyGpsgeGKStlakeLakallkklklkkkdsvys 36 
                   +w+yG++g+GKS+la  +++++++++++k +   y+
    EEA21025.1 320 LWIYGAAGTGKSVLASMVIDHFSQDSNQKDHAVAYV 355
                   6**********************9997776665555 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 4.9
  RNA_helicase  51 evvvidDfgqvkde 64 
                    v +id + +++++
    EEA21025.1 423 VVAIIDGLDECEEK 436
                   34555555555555 PP

>> KAP_NTPase  KAP family P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.0     0.011        16      22      58 ..     319     355 ..     282     363 .. 0.82
   2 !    9.4   0.1   0.00038      0.57     163     197 ..     411     445 ..     396     459 .. 0.77

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.011
  KAP_NTPase  22 vvgLygkWGsGKssllnkledelkefakpvrflfaef 58 
                 ++ +yg+ G+GKs l  +++d  ++ ++++++++a++
  EEA21025.1 319 PLWIYGAAGTGKSVLASMVIDHFSQDSNQKDHAVAYV 355
                 5779**********************99999999985 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.00038
  KAP_NTPase 163 dmektLdalqkrlVvviDdLDrceteevlqlleav 197
                  m+ + + + +r+V +iD+LD ce +  + +l+ +
  EEA21025.1 411 TMFIECAGSLSRVVAIIDGLDECEEKSRKPILDFI 445
                 44444445789*************99988888766 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0     3e-05     0.044      23      63 ..     320     361 ..     306     394 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 3e-05
                 EEEEESTTSSHHHHHHHHCCSHCCCCCCBT.EEEEEEEESXX CS
      NB-ARC  23 valvGmgGvGKttlakqilnksdevegrFd.svawvvvsktd 63 
                 + ++G +G GK++la+ ++ ++++  ++ d  va+v +  +d
  EEA21025.1 320 LWIYGAAGTGKSVLASMVIDHFSQDSNQKDhAVAYVYIKGED 361
                 679*******************99888877677777665554 PP

>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   6.3e-05     0.094       1      74 [.     789     874 ..     789     881 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 6.3e-05
       Ank_2   1 LhlAakngnlelvklLl.egadpn..k.ngktaLhyAakng..nleivklLleh......adndgrtpLhyAarsghleivklLle 74 
                 Lh+ a+ g +++v  L+  g+dpn  +    taL++   +   ++ iv +Ll++      a+++gr+p  +A   +++++v++L e
  EEA21025.1 789 LHITAMTGLDDVVGELIeRGVDPNreDtGSFTALQALSDAEecSETIVIMLLKAggdpykATKSGRSPYEHAQNRKREKFVQILSE 874
                 89999999669*************8544447888866665422334589999866667677799********866899****9974 PP

>> DUF2075  Uncharacterized conserved protein (DUF2075)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   6.4e-05     0.095       6      37 ..     322     353 ..     320     362 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 6.4e-05
     DUF2075   6 VtGvaGtGKtvvllnllaeleddeeertavyl 37 
                 + G+aGtGK+v+++ ++   ++d++++ ++++
  EEA21025.1 322 IYGAAGTGKSVLASMVIDHFSQDSNQKDHAVA 353
                 89***********9999999555555554444 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   6.9e-05       0.1      12      55 ..     309     356 ..     307     437 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 6.9e-05
    ATPase_2  12 eeilerepneiyfiYGpegsGKtaLlkeiienl.edkdk...yviyyi 55 
                 e++++++   ++ iYG  g GK+ L   +i    +d+++    v y++
  EEA21025.1 309 EKWVSEQCTGPLWIYGAAGTGKSVLASMVIDHFsQDSNQkdhAVAYVY 356
                 78999********************99999887333322444666665 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   0.00052      0.78       1      56 []     804     860 ..     804     860 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00052
       Ank_5   1 LlehgpadvnrldgggntpLhvAak.ygaad.vvrlLlargadlnltdsrGltaldlA 56 
                 L+e+g +d+nr+d g++t+L   +    +++ +v++Ll+ g d+   +++G++++++A
  EEA21025.1 804 LIERG-VDPNREDTGSFTALQALSDaEECSEtIVIMLLKAGGDPYKATKSGRSPYEHA 860
                 78999.9**********999999997777752555555*****************998 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00022      0.33       3      51 ..     322     377 ..     320     477 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00022
                 EESSTTSSHHHHHHHHHHHHT.........HEEEEEETTTCSSSSTTHHHHHHHHHHH CS
         AAA   3 lyGppGtGKTllakavakelg.........vefleisgsellskyvgesekkirelfk 51 
                 +yG  GtGK+ la+ v+ +++         v ++ i+g + +  + g  ++ +++l+k
  EEA21025.1 322 IYGAAGTGKSVLASMVIDHFSqdsnqkdhaVAYVYIKGEDTT--LRGSPSRIVSMLIK 377
                 89*****************84333333444668888888888..44444444444444 PP

>> Goodbye  fungal STAND N-terminal Goodbye domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00022      0.33      33     119 ..      79     164 ..      63     166 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00022
     Goodbye  33 qieaekdkfeefrekkeklkealkkilspiqllggiaaqgasmaFgPaslcfnAvsyLikaakkvseiydaieeLfeelsdflerle 119
                  ie+ ++  + +++ ++++   + ++l+ i+++   a+ g+++    +s++ + +  +i++a k+ e y+++++++eel d  + l+
  EEA21025.1  79 TIEDMDK-LHLQETASRRIAGPTLRFLRAIETVMAGATIGIQAYPDVSSIIVGIIRVVINVAVKYFEYYEKLSKMLEELVDDIQVLD 164
                 5555444.333445555566666677777877777777777655446*******************************998777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (891 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       592  (0.0330191); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.75u 0.29s 00:00:01.04 Elapsed: 00:00:00.44
# Mc/sec: 6110.89
//
Query:       EEA21026.1  [L=179]
Description: hypothetical protein PMAA_048290 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00016   22.1   0.0    0.00021   21.7   0.0    1.2  1  Goodbye   fungal STAND N-terminal Goodbye domain


Domain annotation for each model (and alignments):
>> Goodbye  fungal STAND N-terminal Goodbye domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.7   0.0   1.2e-08   0.00021      17     121 .]      33     133 ..      17     133 .. 0.80

  Alignments for each domain:
  == domain 1  score: 21.7 bits;  conditional E-value: 1.2e-08
     Goodbye  17 kdealkelssvedllkqieaekdkfeefrekkeklkealkkilspiqllggiaaqgasmaFgPaslcfnAvsyLikaakkvseiydaieeLfeelsdfl 115
                 ++++++++ ++e+ +k++++++     +++  +k+ + +  +l++i ll + a+ +++ a    s++++    +i+aa ++ e y++++e++e l   l
  EEA21026.1  33 SHQHTQTPLQIEETMKKLDKDHL----DESLLRKISDRTLGFLQVIDLLMRGATVAVQGAPSVGSVVLGVFRVVIDAAVRYLEYYEKLTEMMEYLIGLL 127
                 667788999**********9999....45666777777777777777776666666666644489****************************998888 PP

     Goodbye 116 erleiY 121
                  ++ +Y
  EEA21026.1 128 HTVGVY 133
                 777666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (179 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       593  (0.0330749); expected 358.6 (0.02)
Passed bias filter:                      469  (0.0261587); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 1269.61
//
Query:       EEA21027.1  [L=668]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.2e-09   36.5   0.0      8e-09   35.6   0.0    1.5  1  NACHT         NACHT domain
    3.6e-05   24.2   0.0    9.1e-05   22.9   0.0    1.7  1  AAA_16        AAA ATPase domain
    5.3e-05   23.7   0.8       0.08   13.5   0.0    3.4  3  Ank_2         Ankyrin repeats (3 copies)
    0.00098   19.1   0.0     0.0016   18.4   0.0    1.4  1  ATPase_2      ATPase domain predominantly from Archaea
      0.001   19.4   0.0     0.0026   18.1   0.0    1.7  1  RNA_helicase  RNA helicase
      0.002   18.4   0.4        0.2   12.0   0.1    3.4  2  Ank_5         Ankyrin repeats (many copies)
  ------ inclusion threshold ------
      0.017   14.6   0.0        0.3   10.5   0.0    2.5  3  PhoH          PhoH-like protein
       0.02   15.3   1.7        1.1    9.8   1.3    3.7  3  Ank           Ankyrin repeat
       0.02   14.1   0.0       0.07   12.3   0.0    1.9  1  NB-ARC        NB-ARC domain
      0.028   14.7   0.0      0.073   13.3   0.0    1.7  1  AAA_22        AAA domain
      0.029   13.6   0.2       0.25   10.5   0.0    2.1  2  KAP_NTPase    KAP family P-loop domain
       0.03   14.1   0.0      0.054   13.2   0.0    1.4  1  IstB_IS21     IstB-like ATP binding protein
      0.031   14.6   0.0      0.083   13.2   0.0    1.7  1  AAA_19        AAA domain
       0.07   12.2   0.0       0.16   11.0   0.0    1.6  1  Parvo_NS1     Parvovirus non-structural protein NS1
      0.079   12.7   0.0       0.14   11.9   0.0    1.4  1  AAA_11        AAA domain
      0.079   13.4   0.0       0.17   12.3   0.0    1.5  1  AAA           ATPase family associated with various cellular 
      0.088   12.7   0.0       0.15   12.0   0.0    1.3  1  Rad17         Rad17 P-loop domain
       0.12   11.8   0.0       0.44    9.9   0.0    1.9  2  Mg_chelatase  Magnesium chelatase, subunit ChlI
       0.12   11.6   0.2       0.25   10.5   0.0    1.5  2  DUF2075       Uncharacterized conserved protein (DUF2075)
       0.13   12.9   0.9         87    4.2   0.1    4.1  3  Ank_3         Ankyrin repeat


Domain annotation for each model (and alignments):
>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.6   0.0     9e-12     8e-09       2     100 ..      71     204 ..      70     272 .. 0.71

  Alignments for each domain:
  == domain 1  score: 35.6 bits;  conditional E-value: 9e-12
                 CEEEEC-TTTCHHHHHH.HHHHHHCTS-SCCCC-SEEEEEETTTTTTS-...-HCHHHCCCCTS--SSS-C.......................CHHHH CS
       NACHT   2 lvilqGeaGsGKTtLlq.klalawaegklpqgafklvFflslrelsrsgnarsladllfsqlpepaapvse.......................vwavl 76 
                 +++l+G++G GK++L+   + ++++++k  q++     +++  e++ +   + ++  l++ql++   + +e                        +   
  EEA21027.1  71 ILWLNGPPGTGKSVLASvAINHLIKRSKHTQDT-VIYAYFKGEETNSQYLPTQMISSLVKQLCWALPALPEpaiefysnflmngrrpsfndlesLFLKC 168
                 58**************84577778888888864.34445555555665555899999999999999999999999*******************9999* PP

                 CCSCCCEEEEEE-STT-SS-TCH............. CS
       NACHT  77 lelperlLlilDglDelvtdlgq............k 100
                 l+l+er+  +lDglDe++++ ++            +
  EEA21027.1 169 LKLFERVFVVLDGLDECEQKHRKmilnfvfgigaqS 204
                 ******************987776666666655551 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.0     1e-07   9.1e-05      19     155 ..      64     194 ..      57     211 .. 0.67

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 1e-07
      AAA_16  19 vrsgrpelvllsGesGvGKsslvrellralekd......ggiflrgkcdqlesa.ipysalaqalareellrqlldeaesaeleawrekleealaavpe 110
                 v+++ ++++ l G++G+GKs l+  + ++l k+       +i+++ k ++  s+ +p +++ ++  + +l+ +l + +e  + e ++ +l    +    
  EEA21027.1  64 VNQNKENILWLNGPPGTGKSVLASVAINHLIKRskhtqdTVIYAYFKGEETNSQyLPTQMISSLV-K-QLCWALPALPEP-AIEFYSNFLMN-GR---- 154
                 5566779****************999999998888888635556666665522225545555555.5.666666666444.44444443322.22.... PP

      AAA_16 111 lagaea..srllellkrllallsrderplvlvlDdlqwadeaslql.l 155
                      +  ++l  l+ ++l+l +r    + +vlD l+  ++  +++ l
  EEA21027.1 155 ----RPsfNDLESLFLKCLKLFER----VFVVLDGLDECEQKHRKMiL 194
                 ....22447777777777777777....9*******998888777744 PP

>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0       5.6     5e+03      12      36 ..     419     443 ..     411     453 .. 0.59
   2 !   10.6   0.1   0.00074      0.66       2      73 ..     537     619 ..     536     620 .. 0.72
   3 !   13.5   0.0   8.9e-05      0.08      17      73 ..     577     662 ..     573     666 .. 0.62

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 5.6
       Ank_2  12 lvklLlegadpnkngktaLhyAakn 36 
                 ++++L++ ++p ++ +t L y+a++
  EEA21027.1 419 CLQHLMSDTEPQDFFETCLSYCAEH 443
                 5566663333333447888888774 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00074
       Ank_2   2 hlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnlei.vklLleh.......adndgrtpLhyAarsghleivklLl 73 
                 +lAa++g +++++ ++ +g+++n  + +  taLh+A+    l++ + +  ++        ++d +tpL +A  ++ + +vk+++
  EEA21027.1 537 FLAALFGLDDILEKIIfQGVNINgaTaDRFTALHLAIGIL-LDAgADWNYDArhvssgnPREDYQTPLNAALLHQAYTAVKIMV 619
                 5799999679*****99****998537999******9852.2333333333223444344467789999999999999999876 PP

  == domain 3  score: 13.5 bits;  conditional E-value: 8.9e-05
       Ank_2  17 l.egadpn....k........ngktaLhyAakn..........gnleivklLleh......adndgrtpLhyAarsghleivklLl 73 
                 l +gad n    +        + +t+L +A  +          g+++ +++L+++       d++g t+L +    g++++v++L 
  EEA21027.1 577 LdAGADWNydarHvssgnpreDYQTPLNAALLHqaytavkimvGHNHYIRILVAQggninqRDEYGDTALRIVRDDGRQDCVEILE 662
                 45565555443313334455566888888888733333333444445566666547776655599******99888*******995 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.0   1.8e-06    0.0016      10     129 ..      59     184 ..      55     267 .. 0.71

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 1.8e-06
    ATPase_2  10 eleeilerepneiyfiYGpegsGKtaL....lkeiienledkdkyviyyialreesiskldefieeeeekkklekal...giavpkaeleeilk...ek 98 
                 + ++++++++++i+ + Gp g GK+ L    ++++i+++++ ++ viy +   ee +s++  +    +  ++l k+l   + a+p+ ++e  ++   + 
  EEA21027.1  59 SFKSWVNQNKENILWLNGPPGTGKSVLasvaINHLIKRSKHTQDTVIYAYFKGEETNSQYLPT----QMISSLVKQLcwaLPALPEPAIEFYSNflmNG 153
                 6789**********************9333345555555666669***776666666655554....33333444444553444444443333344456 PP

    ATPase_2  99 sklvfkaielllekikkkgkkiiiiiDelqk 129
                 ++  f+ +e+l+ k  k   ++ +++D l +
  EEA21027.1 154 RRPSFNDLESLFLKCLKLFERVFVVLDGLDE 184
                 6666777777777777777777777776655 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   2.9e-06    0.0026       1      48 [.      72     119 ..      72     126 .. 0.88

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 2.9e-06
  RNA_helicase   1 iwlyGpsgeGKStlakeLakallkklklkkkdsvysrnpeddfwdgYt 48 
                   +wl Gp+g+GKS+la   +++l k++k +++  +y+  + ++  ++Y 
    EEA21027.1  72 LWLNGPPGTGKSVLASVAINHLIKRSKHTQDTVIYAYFKGEETNSQYL 119
                   6*************************9999999999888888888775 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0      0.38   3.4e+02      30      56 .]     546     572 ..     538     574 .. 0.56
   2 !   12.0   0.1   0.00022       0.2      17      55 ..     600     648 ..     586     649 .. 0.82

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.38
       Ank_5  30 dvvrlLlargadlnltdsrGltaldlA 56 
                 d++++++  g+++n  +++  tal+lA
  EEA21027.1 546 DILEKIIFQGVNINGATADRFTALHLA 572
                 555555555666666666666666655 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 0.00022
       Ank_5  17 ntpLhvAakygaadvvrlLl..........argadlnltdsrGltaldl 55 
                 +tpL+ A  ++a + v++++          a g ++n++d++G+tal +
  EEA21027.1 600 QTPLNAALLHQAYTAVKIMVghnhyirilvAQGGNINQRDEYGDTALRI 648
                 488888888888888888888888888888****************987 PP

>> PhoH  PhoH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00034       0.3      18      49 ..      68      99 ..      57     121 .. 0.79
   2 ?    0.5   0.0       0.4   3.6e+02     118     160 ..     172     219 ..     170     268 .. 0.75
   3 ?   -2.2   0.0       2.6   2.4e+03      72     119 ..     336     383 ..     328     386 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00034
                H-SEEEEE--TTSSTTHHHHHHHHHHHHTTS- CS
        PhoH 18 kndivfaiGpaGtGKtylavalavealkkkkv 49
                k++i+   Gp GtGK+ la ++  +++k++k 
  EEA21027.1 68 KENILWLNGPPGTGKSVLASVAINHLIKRSKH 99
                77899**************8876666666444 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.4
                 B-SEEEEE-SGGG--HHHHHHHHT...TB-TT-E..EEEEE------- CS
        PhoH 118 lndafvilDEAQnttkeqmkmflt...RlGensk..vvvtGdvtqidl 160
                 +++ fv+lD   ++++++ km+l     +G +s    +++ + +qid+
  EEA21027.1 172 FERVFVVLDGLDECEQKHRKMILNfvfGIGAQSEdaKIFVASRKQIDI 219
                 678999999999888888888774111566665422455566666665 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 2.6
                 ------TTTHHHHHHHTTTS-TTCHHHHHHTTSEEEEEGGGGTT--B- CS
        PhoH  72 leekvdpylrplydaLkdllgaekvekllekgkievaplaymRGrTln 119
                 l+ kv     +l+da++ + +   +e+++  g + +  + y R rT++
  EEA21027.1 336 LNAKVVLTSGTLIDAVSLTQDYGPTEEAVTFGLLTIGIIPYFRVRTIH 383
                 678888889999999999999999999999999999999999999987 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0       5.5     5e+03       8      28 ..     538     559 ..     530     562 .. 0.81
   2 ?    9.8   1.3    0.0013       1.1       2      31 ..     565     639 ..     564     640 .. 0.73
   3 ?   -2.3   0.0       8.3   7.4e+03       1      10 [.     641     649 ..     641     666 .. 0.56

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 5.5
                 HHHHHTTHHHHHHHH.TTTSTT CS
         Ank   8 lAatngkkriiklLL.hGAnln 28 
                 lAa +g  +i++ ++ +G n+n
  EEA21027.1 538 LAALFGLDDILEKIIfQGVNIN 559
                 7888888899999999999988 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.0013
                 SBBHHHHH..........................................H..HHTTHHHHHHHH.TTTSTTCBT CS
         Ank   2 GnTPLHlA..........................................a..tngkkriiklLL.hGAnlnald 31 
                  +T+LHlA                                          +  + g+ + i+ L+ +G n+n++d
  EEA21027.1 565 RFTALHLAigilldagadwnydarhvssgnpredyqtplnaallhqaytaVkiMVGHNHYIRILVaQGGNINQRD 639
                 58*****8777777777777777777777777777777776666665554155888888******9988***998 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 8.3
                 TSBBHHHHHH CS
         Ank   1 dGnTPLHlAa 10 
                 +G+T+L + +
  EEA21027.1 641 YGDTALRI-V 649
                 69999977.6 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   7.8e-05      0.07      20      57 ..      69     107 ..      57     283 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 7.8e-05
                 SEEEEEEESTTSSHHHHHHHHCCSHCCCCC.CBTEEEEE CS
      NB-ARC  20 slvvalvGmgGvGKttlakqilnksdeveg.rFdsvawv 57 
                   ++ l G +G GK++la+ ++n++ +  + + d v++ 
  EEA21027.1  69 ENILWLNGPPGTGKSVLASVAINHLIKRSKhTQDTVIYA 107
                 36999**************99999655443277777665 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   8.2e-05     0.073       4      56 ..      68     119 ..      65     198 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 8.2e-05
      AAA_22   4 tagilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsst.sskdl 56 
                 +++il + G++GtGK++l+    + l +++k++  +++v++ + ++++ +s+ l
  EEA21027.1  68 KENILWLNGPPGTGKSVLASVAINHLIKRSKHT--QDTVIYAYFKGEEtNSQYL 119
                 67899999****************996666665..5666666666665344444 PP

>> KAP_NTPase  KAP family P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0      0.34   3.1e+02      22      78 ..      71     128 ..      62     136 .. 0.67
   2 ?   10.5   0.0   0.00028      0.25     171     202 ..     171     202 ..     154     227 .. 0.76

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.34
  KAP_NTPase  22 vvgLygkWGsGKssllnkledelkefa..kpvrflfaefnawsfkggddavaellaaLa 78 
                 ++ L+g+ G+GKs l    ++ l +++   +++++ a+f+   +++ + +  +++++L+
  EEA21027.1  71 ILWLNGPPGTGKSVLASVAINHLIKRSkhTQDTVIYAYFKGEETNS-QYLPTQMISSLV 128
                 56799999*****996665555555542226666667776666654.555566666665 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00028
  KAP_NTPase 171 lqkrlVvviDdLDrceteevlqlleavkllfs 202
                 l  r++vv+D+LD ce++  + +l+ v  ++ 
  EEA21027.1 171 LFERVFVVLDGLDECEQKHRKMILNFVFGIGA 202
                 4689********************99987665 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   6.1e-05     0.054      39      67 ..      59      89 ..      32     108 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 6.1e-05
   IstB_IS21 39 atlsfiek.keniv.llGpsGvGKshlaial 67
                   s++++ keni+ l Gp+G+GKs la   
  EEA21027.1 59 SFKSWVNQnKENILwLNGPPGTGKSVLASVA 89
                55789975267876478**********9643 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   9.3e-05     0.083       6      48 ..      65     107 ..      61     115 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 9.3e-05
      AAA_19   6 ealkekvllvtaGpGtGKTrvlkhivallvelggvkpeeillv 48 
                 ++ ke++l + ++pGtGK+ +   ++++l+++ +   ++++ +
  EEA21027.1  65 NQNKENILWLNGPPGTGKSVLASVAINHLIKRSKHTQDTVIYA 107
                 567889999**********************998876665554 PP

>> Parvo_NS1  Parvovirus non-structural protein NS1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00018      0.16     106     143 ..      63      99 ..      50     111 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00018
   Parvo_NS1 106 wlskqlgkrntvwfyGpantGktnlae.aIakavplygc 143
                 w++++  k n +w+ Gp+ tGk+ la+ aI + +++ ++
  EEA21027.1  63 WVNQN--KENILWLNGPPGTGKSVLASvAINHLIKRSKH 99 
                 55555..99*****************9888888877766 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   0.00016      0.14      16      46 ..      66      98 ..      56     122 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00016
      AAA_11 16 ese..itliqGPPGtgKTktivellsqllsrrk 46
                +++  i  + GPPGtgK+      +++l++r+k
  EEA21027.1 66 QNKenILWLNGPPGTGKSVLASVAINHLIKRSK 98
                444448999*********998888888875522 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   0.00019      0.17       3      22 ..      74      93 ..      72     131 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00019
                EESSTTSSHHHHHHHHHHHH CS
         AAA  3 lyGppGtGKTllakavakel 22
                l GppGtGK+ la+  +++l
  EEA21027.1 74 LNGPPGTGKSVLASVAINHL 93
                88************999987 PP

>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   0.00017      0.15       8      73 ..      28      96 ..      21     160 .. 0.63

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00017
       Rad17  8 lWfekykPekaeelavhkkkieevkewl.kadvLesrkkr....iLLisGPsGCgkstvvkvLskelgikl 73
                 W+ k+  e++++  +  k+ ++   wl ++d+ +s  ++    iL + GP+G gks    v   ++ ik 
  EEA21027.1 28 DWICKHDVETLHDE-IDNKRHKDTGSWLlETDSFKSWVNQnkenILWLNGPPGTGKSVLASVAI-NHLIKR 96
                68888888888884.66777788888862577765433333335************96544433.333333 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0   0.00049      0.44      25      47 ..      72      94 ..      66     120 .. 0.74
   2 ?   -2.2   0.0       2.5   2.2e+03     121     145 ..     297     321 ..     290     332 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00049
  Mg_chelatase 25 lllvGppGsGKtmlakrlpsllp 47
                  l l GppG+GK++la+   + l 
    EEA21027.1 72 LWLNGPPGTGKSVLASVAINHLI 94
                  5689***********96544333 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 2.5
  Mg_chelatase 121 kvlevLRePledgevtisrakakve 145
                   + le L + led+ v+i r+ +++ 
    EEA21027.1 297 RQLELLPSGLEDTYVSIFRKMNTLP 321
                   56999999***********988765 PP

>> DUF2075  Uncharacterized conserved protein (DUF2075)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       2.7   2.4e+03     215     275 ..      17      67 ..       9      75 .. 0.48
   2 ?   10.5   0.0   0.00028      0.25       5      38 ..      73     108 ..      69     119 .. 0.73

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 2.7
     DUF2075 215 lkeknkesgrsrlvatydakrl.ae.kkkkkskekdvkieegdfklpWnleekelkkpwaess 275
                 lk++++  +   +++  d + l +e ++k++++ +           +W le++ + k+w++++
  EEA21027.1  17 LKAQKERRDFLDWICKHDVETLhDEiDNKRHKDTG-----------SWLLETD-SFKSWVNQN 67 
                 45555555556666666666662221222233333...........4555555.333444443 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00028
     DUF2075   5 lVtGvaGtGKtvvllnllael..eddeeertavyls 38 
                   +G +GtGK+v+++ +++ l  +++  + t++y++
  EEA21027.1  73 WLNGPPGTGKSVLASVAINHLikRSKHTQDTVIYAY 108
                 5689***********999999554445555566655 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0      0.12   1.1e+02       7      30 ..     537     559 ..     529     560 .. 0.89
   2 ?   -0.7   0.0       3.9   3.5e+03       3      10 ..     566     573 ..     564     575 .. 0.84
   3 ?    4.2   0.1     0.096        87       2      24 ..     599     621 ..     598     637 .. 0.75

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.12
       Ank_3   7 hlAarsgnleivkfLlenkgadvn 30 
                 +lAa++g  +i++ ++   g+++n
  EEA21027.1 537 FLAALFGLDDILEKIIF-QGVNIN 559
                 48***************.9****9 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 3.9
       Ank_3   3 etpLhlAa 10 
                  t+LhlA+
  EEA21027.1 566 FTALHLAI 573
                 59****97 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.096
       Ank_3   2 GetpLhlAarsgnleivkfLlen 24 
                 ++tpL  A++++ ++ vk ++ +
  EEA21027.1 599 YQTPLNAALLHQAYTAVKIMVGH 621
                 79************987766663 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (668 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       730  (0.0407162); expected 358.6 (0.02)
Passed bias filter:                      665  (0.0370907); expected 358.6 (0.02)
Passed Vit filter:                        88  (0.00490825); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              20  [number of targets reported over threshold]
# CPU time: 0.71u 0.27s 00:00:00.98 Elapsed: 00:00:00.44
# Mc/sec: 4564.94
//
Query:       EEA21028.1  [L=634]
Description: glucosyltransferase (Die2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
   6.1e-123  411.0   4.4     1e-122  410.3   4.4    1.4  1  DIE2_ALG10  DIE2/ALG10 family
  ------ inclusion threshold ------
      0.051   13.0   6.8      0.071   12.5   6.8    1.1  1  SDA1        SDA1
       0.22   11.5   7.9       0.34   10.9   7.9    1.2  1  DUF4674     Domain of unknown function (DUF4674)
        6.4    7.1   7.0        9.4    6.6   4.4    2.2  2  Phage_Gp23  Protein gp23 (Bacteriophage A118)


Domain annotation for each model (and alignments):
>> DIE2_ALG10  DIE2/ALG10 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  410.3   4.4  2.3e-126    1e-122       1     396 []      35     568 ..      35     568 .. 0.91

  Alignments for each domain:
  == domain 1  score: 410.3 bits;  conditional E-value: 2.3e-126
  DIE2_ALG10   1 vpepylDEiFHvpQaqkYckgkfkeWdpkiTTpPGLYllsvlllkllklelslselcslavlRlvnllllllllplllrrllkkkkkeskekk....av 95 
                 v+epylDE+FHv Qaq+Y+++++ +WdpkiTTpPGLYl s+l  +  +l + +s++ s+  lR++n +++++llp+ l++ll+  +ke+++++     +
  EEA21028.1  35 VQEPYLDEVFHVGQAQTYWRHDWFNWDPKITTPPGLYLWSYLDCTGRSLLKGSSDVVSVFDLRFTNSIAAAFLLPWRLQTLLDLIRKEKNTRAagawLS 133
                 689**************************************99988888888999****************************9999998888899999 PP

  DIE2_ALG10  96 lsalnlalfPllfffsfLYYTDvlStllvllayllalkkk.....kkls.................allglvsllfRQTNivWv.vfvaglevvktlee 171
                 ++ ln++lfP+lfffs LYYTD+l++++v++ay+  ++++     k  +                 +++g+++l+fRQTNi+Wv vf+ gl+vv+t+++
  EEA21028.1 134 HTVLNICLFPPLFFFSGLYYTDILALIVVIQAYIWDTERSdangqK--KtavdalrchvslktlafITIGCIALVFRQTNIFWVsVFMGGLQVVRTIRQ 230
                 9*******************************99888888555541..04456666666677777799******************************* PP

  DIE2_ALG10 172 akkkkkkskkeekslk..............eledllklllsllsslkkllkkllkilkkllpyllvlvlFaaFvvwNggivlGdksnHeatlhlpQllY 256
                 ++k++ +s   e ++k              +l d+lk+ lsl  ++   l++l  ++++++p+l++l +F aFv+wNgg+vlG+k+ H+a++hlpQ+lY
  EEA21028.1 231 NTKSCGRSGPLEIMAKsfqaelydplveeaSLADYLKTGLSLGCAA---LSELPLVVASIIPHLIILGAFGAFVLWNGGVVLGHKEFHTAGIHLPQMLY 326
                 ******98877666558999*******9998899999999998866...788999******************************************** PP

  DIE2_ALG10 257 fllfiaffslplllskll...klkellkallklsllslll......tllllllillivkkftivHpflLADNRHYtFYiwrrllkrhplikyllvpvYl 346
                 ++++++ffs+pl+   +l     ++++ ++l  +l++++       +l+++ l+ ++v+++tivHpf+LADNRHY+FY++r l + hp++ky++vpvYl
  EEA21028.1 327 IWPYFVFFSFPLISIGVLnavVPRRFIPKYLDYNLSNAHRlpsiltALAIIPLMSAAVHFNTIVHPFTLADNRHYVFYVFRVLTRVHPAVKYAAVPVYL 425
                 ************98766677744555555555555444336666668899999********************************************** PP

  DIE2_ALG10 347 lslwlvlealaksks.................................................................................... 361
                 l++w+vl+a+   ++                                                                                    
  EEA21028.1 426 LCGWAVLAAFGLFSPpppkappiqiatpqegfpsypetqkpskrqekeakkqqkkqesktnsdkkspstvaklkqsdqqthvltpellakiqahialrq 524
                 **********8555579********************************************************************************** PP

  DIE2_ALG10 362 .........vllvlalllatllslvpapLlEpRYfiiPyvllrl 396
                          v++vl++l+at lsl++apL+EpRYfiiP+v++rl
  EEA21028.1 525 qqrdnqrvrVSFVLIWLIATSLSLITAPLVEPRYFIIPWVIWRL 568
                 ******************************************97 PP

>> SDA1  SDA1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   6.8   1.6e-05     0.071     170     223 ..     467     520 ..     454     535 .. 0.59

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.6e-05
        SDA1 170 eeeeekekkkkkakeaseeekkkekeeekiskaselattrILTpaDFaklkelr 223
                 ++++eke+kk+++k++s+++++k+++++ ++ +++ ++t++LTp+ +ak+++  
  EEA21028.1 467 SKRQEKEAKKQQKKQESKTNSDKKSPSTVAKLKQSDQQTHVLTPELLAKIQAHI 520
                 222223333333444444444555555555544689**************9865 PP

>> DUF4674  Domain of unknown function (DUF4674)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   7.9   7.6e-05      0.34     103     165 ..     455     517 ..     446     536 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 7.6e-05
     DUF4674 103 eetpksksslktkkkktksskkktktsvsksnskgkspaltfrspssgqstsvssskskkkkk 165
                 e+ p   + +k  k+++k++kk++k ++sk ns +ksp+ + + ++s q+t v + +   k +
  EEA21028.1 455 EGFPSYPETQKPSKRQEKEAKKQQKKQESKTNSDKKSPSTVAKLKQSDQQTHVLTPELLAKIQ 517
                 5556666677777888888888888999***********************996555555555 PP

>> Phage_Gp23  Protein gp23 (Bacteriophage A118)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.0      0.22   9.7e+02      18      42 ..     147     172 ..     136     180 .. 0.72
   2 ?    6.6   4.4    0.0021       9.4      51      88 ..     468     505 ..     462     524 .. 0.76

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.22
  Phage_Gp23  18 lfaalsvv.lflillivtkriwddrk 42 
                 +f+ l+ + ++ +++++ + iwd ++
  EEA21028.1 147 FFSGLYYTdILALIVVIQAYIWDTER 172
                 56666554144455678999***877 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0021
  Phage_Gp23  51 erekkeekrekkekeskeekdkti.ssvdkskrlldkqn 88 
                  r+ ke+k+++k++esk + dk   s+v k k+  d+q 
  EEA21028.1 468 KRQEKEAKKQQKKQESKTNSDKKSpSTVAKLKQ-SDQQT 505
                 7999**************999865255655443.45555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (634 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2095  (0.11685); expected 358.6 (0.02)
Passed bias filter:                     1091  (0.0608511); expected 358.6 (0.02)
Passed Vit filter:                       149  (0.00831056); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.91u 0.32s 00:00:01.23 Elapsed: 00:00:00.48
# Mc/sec: 3962.81
//
Query:       EEA21029.1  [L=272]
Description: DNA replication complex GINS protein (Psf2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-31  109.5   0.0    5.1e-31  107.4   0.0    2.0  2  Sld5      GINS complex protein


Domain annotation for each model (and alignments):
>> Sld5  GINS complex protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0      0.86   1.5e+04      11      29 ..      17      33 ..      15      39 .. 0.58
   2 !  107.4   0.0   2.8e-35   5.1e-31       2     109 .]      51     225 ..      50     225 .. 0.99

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 0.86
                HHHTTSCCCHHCHHHCHHH CS
        Sld5 11 Lkrqrrveieppewlspes 29
                L+++  v+++p + l  e+
  EEA21029.1 17 LSEMEMVTVVPRQRL--EE 33
                556666666666665..33 PP

  == domain 2  score: 107.4 bits;  conditional E-value: 2.8e-35
                 EEEHHHHHHHHHTTSCCCHHCHHHCHHHHHHCCCHHTTS............................................................ CS
        Sld5   2 eLPlWlaelLkrqrrveieppewlspesleailedetks............................................................ 40 
                  LPlWla lLkrqrrv+i+pp wl+pe l+ il+ et++                                                            
  EEA21029.1  51 TLPLWLAILLKRQRRVNIVPPHWLHPECLQIILQFETETkeysdtfspppilpgqrraaddgrrqpaapprpkytldgqryyptppflpqntaltaaet 149
                 69************************************************************************************************* PP

                 ...SSSTTTTTTHHHHHHHHHHHHT.....HCHHHHHHHHHHHHHHHHHHHTHCHHHHHHHTS-TCCHCCS-HHHH CS
        Sld5  41 ...sdlpslpphflelavkllelard....ldelkrllrdllevRlakirkfaenledaagggggellsglseeEk 109
                    ++  +lp+h+le++++ll++a+d    +d ++rll+dl+evR++k+rk +++l++aa+ g+g+ l+g++++E+
  EEA21029.1 150 qdmEREIALPYHWLEVGNMLLDAASDdltePDHVRRLLKDLREVRMSKMRKRVDSLDAAATAGNGVSLTGVGAMEI 225
                 ***9999******************99************************************************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (272 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       339  (0.0189079); expected 358.6 (0.02)
Passed bias filter:                      279  (0.0155614); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.28s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 1864.74
//
Query:       EEA21030.1  [L=191]
Description: AMFR protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-10   40.9   0.0    1.9e-10   40.2   0.0    1.4  1  CUE       CUE domain
  ------ inclusion threshold ------
      0.013   15.1   9.1      0.031   13.9   9.1    1.6  1  G2BR      E3 gp78 Ube2g2-binding region (G2BR)
      0.036   14.0   2.9      0.054   13.4   2.9    1.2  1  DUF1151   Protein of unknown function (DUF1151)


Domain annotation for each model (and alignments):
>> CUE  CUE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.2   0.0   3.2e-14   1.9e-10       2      41 ..      50      89 ..      49      90 .. 0.95

  Alignments for each domain:
  == domain 1  score: 40.2 bits;  conditional E-value: 3.2e-14
                HHHHHHHHHHSTTS-HHHHHHHHHHCTTTHHHHHHHHHHC CS
         CUE  2 eqmletLkemFPdldeevIravLrasngnvEatinaLLeg 41
                + ++e++++mFP+l + +I ++L++++g+v at++++L g
  EEA21030.1 50 PAQVEQISQMFPQLNRRDIMWDLQRNGGSVAATTERILTG 89
                679***********************************88 PP

>> G2BR  E3 gp78 Ube2g2-binding region (G2BR)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   9.1   5.2e-06     0.031       4      23 ..     156     175 ..     155     179 .. 0.94

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 5.2e-06
        G2BR   4 ERQRMLvqRKEdLLqqARRR 23 
                 ERQR L  R +d+++ ARR 
  EEA21030.1 156 ERQRLLQKRRDDMILAARRK 175
                 9*****************95 PP

>> DUF1151  Protein of unknown function (DUF1151)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   2.9   9.1e-06     0.054      31      72 ..     142     184 ..     126     188 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 9.1e-06
     DUF1151  31 lnqkr.glvleeKpELqrvlekrkeeqvlkqkkeeeeakkkks 72 
                 ++ k   +  ++K+E qr l+kr+ + +l+++++ +++++ +s
  EEA21030.1 142 ISSKPqSAWSQNKSERQRLLQKRRDDMILAARRKLQQKDRETS 184
                 555654566789******************9999888888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (191 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       880  (0.0490825); expected 358.6 (0.02)
Passed bias filter:                      429  (0.0239277); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.46
# Mc/sec: 1261.33
//
Query:       EEA21031.1  [L=1179]
Description: nuclear condensin complex subunit Smc2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      1e-69  234.4   4.3    6.3e-69  231.8   4.3    2.2  1  SMC_N         RecF/RecN/SMC N terminal domain
    7.7e-21   74.6   0.4    4.6e-20   72.1   0.1    2.5  2  SMC_hinge     SMC proteins Flexible Hinge Domain
    3.2e-11   44.1  13.8    3.2e-11   44.1  13.8    6.6  6  AAA_23        AAA domain
      8e-10   39.0   7.9     0.0002   21.2   0.2    3.8  4  AAA_21        AAA domain, putative AbiEii toxin, Type IV TA s
    7.8e-05   22.5  16.9    7.8e-05   22.5  16.9    4.5  4  AAA_15        AAA ATPase domain
    0.00013   21.6   0.1    0.00032   20.4   0.1    1.6  1  AAA_29        P-loop containing region of AAA domain
  ------ inclusion threshold ------
       0.31   10.9  17.7       0.27   11.1   0.5    5.2  5  HSBP1         Heat shock factor binding protein 1
        5.9    7.2  14.2        1.7    8.9   3.3    4.1  3  VPS11_C       Vacuolar protein sorting protein 11 C terminal


Domain annotation for each model (and alignments):
>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  231.8   4.3   2.8e-72   6.3e-69       2     215 ..       3    1165 ..       2    1169 .. 0.99

  Alignments for each domain:
  == domain 1  score: 231.8 bits;  conditional E-value: 2.8e-72
                  EEEEEEESETTEECEEEEEETTSSEEEEEESTTSSHHHHHHHHHHHCTT.TTTTTTCHCCCCCC--BTTCSSTTEEEEEEEEEETTEE....SSSSS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxx RF
       SMC_N    2 lkrleienFksyagktvilpfsksftaivGpNGSGKsnlldAilFvLGersakklrseklsdlihkskekasvkkaeveitfdnedkk....lkiek 94  
                  + +++i++Fksya +tvi  +++sf++i+G NGSGKsn+ldAi+FvLG ++++++r+++l+dli+k + +a v+ka+v+i+fdn dk+      +e 
  EEA21031.1    3 IVEIIIDGFKSYAVRTVISGWDESFNSITGLNGSGKSNILDAICFVLGITNMSTVRAQNLQDLIYK-RGQAGVTKASVTIVFDNRDKAkspiGFEEY 98  
                  679**************************************************************9.9******************99855555566 PP

                  SCEEEEEEEETTSEEEEEETTEEE-HHHHHHHHHCTT-STT........................................................ CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........................................................ RF
       SMC_N   95 eevsisrrvkrkgeseykingkevtkkevsellesagiske........................................................ 135 
                   ++s++r+++ +g+s+y ing++++++ v++l++s++++++                                                        
  EEA21031.1   99 GSISVTRQIVLGGTSKYLINGHRAQQQTVQNLFQSVQLNINnpnflimqgritkvlnmkaveilsmieeaagtrmfedrkekaaktmakkemkvrei 195 
                  66*********************************************************************************************** PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA21031.1  196 egllneeiepkleklrgekrafldfqqtqndverltrlvvahdyvkskdrlklageeyeakkqkiqtledsaarlkneiahleedvkrvkavrekel 292 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA21031.1  293 rkggkfqalenevkehshelvrlatvfelknssmadekekrkasqksvaelekllkdkrkvyeklqmkydtakaefdtqtaevetkeellqtlqtgi 389 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA21031.1  390 askegqengyqgqlqdarnrasaalteqeqaklkvthlekrikeeeprakkaveqnsgllkdleslrgraskletemaklgfepgkeeeiyqeqsnl 486 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA21031.1  487 qrairelreradgmnrrvanldfsysdphqgfdrskvkglvaqlftldkekthagtaleicaggrlynvvvdsaetgsqllqngklrkrvtiiplnk 583 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA21031.1  584 isgfkasaekigaaqrlapgkvdlalsligyddevsaamnyvfgstlicedaqtakavtfdpsvrlksvtlegdvydpsgtlsggsspnssgvlvvl 680 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA21031.1  681 qklheinrelrskehqlanlqemmakekkkldavrslkqeldlknheikltedqinsnssssiiqavkemkeqieqlkkdiadaksryaeaqqdikr 777 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA21031.1  778 iekdmkefdnnkddklaelqtsvdtlkkslnknsiavktlhkelqasrleseqagsdlsaaeeqlaeadnamqaqleeietlkkeqtrikdahdiaq 874 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA21031.1  875 aqleeeqakltsfddelgdleqairsknariteesleaqklghqleklhkdqqaaaqmvanmenehewieeekdsfgrpntpydfrgqniaecrstl 971 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA21031.1  972 rnlterfqgmkkkinpkvmnmidsvekkevalknmmktvvrdknkieetiinldeykkealhktwtkvnadfgqifaellpgsfakldppegkeitd 1068
                  ************************************************************************************************* PP

                  .................CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC-SCEEEEEEEE CS
                  .................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  136 .................lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQfivislreemlekadklvgvtkve 215 
                                   +LSgG+++L+al+L++A+ ++kpap+y+lDe+daaLD ++++++ +l+k++ k +Qfiv+sl+++m+++a++++++++ e
  EEA21031.1 1069 glevkvslgkvwkqsltELSGGQRSLIALSLIMALLQFKPAPMYILDEVDAALDLSHTQNIGRLIKTRFKGSQFIVVSLKDGMFQNANRIFRTRFSE 1165
                  *******************************************************************************************998844 PP

>> SMC_hinge  SMC proteins Flexible Hinge Domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.1   0.1   2.1e-23   4.6e-20       2     116 ..     521     641 ..     520     642 .. 0.93
   2 ?   -1.4   0.0       1.3   2.8e+03      78     103 ..     987    1013 ..     971    1032 .. 0.68

  Alignments for each domain:
  == domain 1  score: 72.1 bits;  conditional E-value: 2.1e-23
   SMC_hinge   2 kgvlGrladlievdegye...kAveaalgnrlqalvvedeetakkiieflkkknagratflpldrikqknkadgandkns.....gavplidlvevdde 92 
                 ++v G +a+l+++d++ +   +A+e+ +g+rl ++vv++ et  ++++  k +  +r+t++pl++i+ ++ + ++    +     ++  +++l+ +dde
  EEA21031.1 521 SKVKGLVAQLFTLDKEKThagTALEICAGGRLYNVVVDSAETGSQLLQNGKLR--KRVTIIPLNKISGFKASAEKIGAAQrlapgKVDLALSLIGYDDE 617
                 5699**********6555599**************************988888..79************999999888779****************** PP

   SMC_hinge  93 lrkalryllgdtlvvdsldeAeel 116
                 +++a++y++g tl++++ ++A+++
  EEA21031.1 618 VSAAMNYVFGSTLICEDAQTAKAV 641
                 *********************986 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 1.3
   SMC_hinge   78 sgavplidlvevdde.lrkalryllgd 103 
                  +++  +id ve ++  l+++++ +++d
  EEA21031.1  987 PKVMNMIDSVEKKEVaLKNMMKTVVRD 1013
                  466667777766666666666665554 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.1  13.8   1.4e-14   3.2e-11       2     196 ..       6     264 ..       5     313 .. 0.56
   2 ?   -5.6  16.7         8   1.8e+04     108     196 ..     288     386 ..     265     395 .. 0.59
   3 ?  -16.3  28.9         8   1.8e+04      67     196 ..     333     494 ..     322     498 .. 0.47
   4 ?    3.0  17.5     0.055   1.2e+02     127     199 ..     692     761 ..     673     775 .. 0.66
   5 ?  -12.4  29.2         8   1.8e+04      96     186 ..     777     892 ..     763     933 .. 0.34
   6 ?    0.1   6.8      0.44   9.8e+02     105     192 ..     903    1021 ..     892    1041 .. 0.67

  Alignments for each domain:
  == domain 1  score: 44.1 bits;  conditional E-value: 1.4e-14
      AAA_23   2 Lkienfrsf.rdqeidF.skgltlItGpNGaGKTTildAiklaLygetprlsrksgrgfeksdveiesegkvkayveltfenkdgry.......trsie 91 
                 + i +f+s+  ++ i   +  ++ ItG NG+GK+ ildAi+++L+   +++s+ + +++ +  ++ ++ g +ka+v++ f n d+ +       + si+
  EEA21031.1   6 IIIDGFKSYaVRTVISGwDESFNSITGLNGSGKSNILDAICFVLGI--TNMSTVRAQNLQDLIYKRGQAGVTKASVTIVFDNRDKAKspigfeeYGSIS 102
                 899******65677877799************************97..577888889999999999999*************99998977777744443 PP

      AAA_23  92 rerelskkkgkttkkaklelleideleqfisellgskki..ilnlilflgqer.............................feefelkdkke...... 153
                  +r+   + +++       + ++++++q++++l++s +   +++++l + q+r                             +         +      
  EEA21031.1 103 VTRQIVLGGTSK-----YLINGHRAQQQTVQNLFQSVQLniNNPNFL-IMQGRitkvlnmkaveilsmieeaagtrmfedrkE---------Kaaktma 186
                 333333333322.....223333555555555444222211222222.22333234444444444555544445333332221.........0234444 PP

      AAA_23 154 .......................................rleelekeleeledekkllekl................eqekekekeleeleeeleeil 196
                                                                             +                 ++k   +e+e++++++++++
  EEA21031.1 187 kkemkvreiegllneeiepkleklrgekrafldfqqtqnD--------------------VerltrlvvahdyvkskDRLKLAGEEYEAKKQKIQTLE 264
                 4446555555555554444222222222222222222220....................24444445555444433222222225555555555443 PP

  == domain 2  score: -5.6 bits;  conditional E-value: 8
      AAA_23 108 klelleideleqfisellgskki.........ilnlilflgqer....feefelkdkkerleelekeleeledekkllekl.........eqekekeke 184
                  +++l++  + q ++++++             +l+        +     e++++k+ ++ ++elek l+++ ++ ++l+ +              + +e
  EEA21031.1 288 REKELRKGGKFQALENEVKEHSHelvrlatvfELK--------NssmaDEKEKRKASQKSVAELEKLLKDKRKVYEKLQMKydtakaefdT----QTAE 374
                 44444554455555555555544222222222223........233444445588889999999999999999999999988876544330....3335 PP

      AAA_23 185 leeleeeleeil 196
                  e++ee l++++
  EEA21031.1 375 VETKEELLQTLQ 386
                 555555555544 PP

  == domain 3  score: -16.3 bits;  conditional E-value: 8
      AAA_23  67 segkvkayveltfenkdgrytrsiererelskkkgkttkkaklellei.deleqfisellgskkiilnlilflgqer...................... 142
                  ++++k+++el+   kd+r   ++ ++ + +++ +k   ++++ ++e+ +el q++++ + sk+ + n ++ + q+                       
  EEA21031.1 333 RKASQKSVAELEKLLKDKR---KVYEKLQMKYDTAKAEFDTQTAEVETkEELLQTLQTGIASKEGQENGYQGQLQDArnrasaalteqeqaklkvthle 428
                 3356666777776666663...47666666666666666666666666555556666544444333333332222222333322222112222222221 PP

      AAA_23 143 ...feefel.....kdkkerleelekeleeledekkllekl........eqekekekeleeleeeleeil 196
                    +    +     k+  e+   l k+le l  ++++le++         +e+e  +e ++l++++ e+ 
  EEA21031.1 429 kriK----EeepraKKAVEQNSGLLKDLESLRGRASKLETEmaklgfepGKEEEIYQEQSNLQRAIRELR 494
                 1110....11122233333444444444444444444554477778866456666667777777776665 PP

  == domain 4  score: 3.0 bits;  conditional E-value: 0.055
      AAA_23 127 skkiil.nlilflgqerfeefelkdkkerleelekeleeledekkllekl..........eqekekekeleeleeeleeilkel 199
                 sk+ +l nl        + + ++k+k++++++l++el+ ++ e+kl e++          +       + +e +e++e+++k++
  EEA21031.1 692 SKEHQLaNLQ-------EMMAKEKKKLDAVRSLKQELDLKNHEIKLTEDQinsnssssiiQ-------AVKEMKEQIEQLKKDI 761
                 3333332222.......33444577999**********************77755555544.......4445555555554443 PP

  == domain 5  score: -12.4 bits;  conditional E-value: 8
      AAA_23  96 lskkkgkttkka.klelleideleqfisellgskki.ilnlilflgqer...........feefelkdkke...........rleelekeleeledekk 170
                 +++k++k+ +++ + +l e +++ ++++++l+++ i   +l   l+++r           +        +e           +lee+e+ ++e++ +k+
  EEA21031.1 777 RIEKDMKEFDNNkDDKLAELQTSVDTLKKSLNKNSIaVKTLHKELQASRleseqagsdlsA-------AEEqlaeadnamqaQLEEIETLKKEQTRIKD 868
                 3333333222221222333344444444444444333223333333333222222222221.......1111111111111122222222222222222 PP

      AAA_23 171 llekl.....eqekekek.......ele 186
                            q++e+++       el 
  EEA21031.1 869 ----AhdiaqAQLEEEQAkltsfddELG 892
                 ....122222111222222222222222 PP

  == domain 6  score: 0.1 bits;  conditional E-value: 0.44
      AAA_23  105 kkaklelleideleqfisellgskkiilnlilflgqerfeefelkdkke.........................rleelekeleele.dekkllekl 175 
                     ++e+le ++l  ++++l + +++  ++++ +  e ++ +e+kd +                          r + ++k+++ +  ++++ +ek+
  EEA21031.1  903 ARITEESLEAQKLGHQLEKLHKDQQAAAQMVANMENEHEWIEEEKDSFGrpntpydfrgqniaecrstlrnlteRFQGMKKKINPKVmNMIDSVEKK 999 
                  3446778888999999999999999999999999999999999999888999999999999999888888888866666666666543466666666 PP

      AAA_23  176 ............eqekekekeleeleeel 192 
                                        +++ee++
  EEA21031.1 1000 evalknmmktvvR-------DKNKIEETI 1021
                  5444444443442.......222222222 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.2   9.1e-08    0.0002       1      26 [.      27      56 ..      27      99 .. 0.77
   2 ?   -1.5   0.0       0.8   1.8e+03      66     123 ..     393     450 ..     389     476 .. 0.80
   3 ?   -0.2   0.4      0.32   7.1e+02     116     195 ..     712     785 ..     678     828 .. 0.65
   4 !   19.6   0.0     3e-07   0.00067     233     296 ..    1083    1146 ..    1023    1146 .. 0.88

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 9.1e-08
      AAA_21  1 lnvliGpNgsGKSnLLdaldllarl....d 26
                +n ++G NgsGKSn+Lda+ ++ ++     
  EEA21031.1 27 FNSITGLNGSGKSNILDAICFVLGItnmsT 56
                799****************88877665552 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.8
      AAA_21  66 lsqgvryryglrlersqveeklssvetllesgllldkrsleeedvfnpeargirggvs 123
                 + q++ y++ l+  r++ ++ l+++e+ +++ + l kr++eee++    ++ + g+++
  EEA21031.1 393 EGQENGYQGQLQDARNRASAALTEQEQAKLKVTHLEKRIKEEEPRAKKAVEQNSGLLK 450
                 5678888888888888889999999999********9999999987666666555555 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 0.32
      AAA_21 116 rgirggvsvfslkelsvsepndlqfgkaltditsrawsllllldglrkerigllnifadyfgfakekrllqrlvrslklv 195
                 +  r+++++  lk+++++  +d++++    +i+    + ++  + l        +i+++   +a+ ++ ++r ++  k+ 
  EEA21031.1 712 DAVRSLKQELDLKNHEIKLTEDQINSNSSSSIIQAVKEMKEQIEQL------KKDIADAKSRYAEAQQDIKRIEKDMKEF 785
                 4556777888888888888888888888888888887777777444......3333333333333333333333333333 PP

  == domain 4  score: 19.6 bits;  conditional E-value: 3e-07
      AAA_21  233 parelSdGtkrll..alltallralkkgsllliDEpEngLHPkllrrllellkelsr.ngaQviltT 296 
                  +++elS G+++l+   l+ all+  +  + +++DE+++ L+ + +  + +l+  ++r +g+Q+i+++
  EEA21031.1 1083 SLTELSGGQRSLIalSLIMALLQFKPA-PMYILDEVDAALDLSHTQNIGRLI--KTRfKGSQFIVVS 1146
                  6789********767999999999999.************************..333368***9986 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5  16.9   3.5e-08   7.8e-05       1     235 [.       1     417 [.       1     505 [. 0.57
   2 ?   -5.8  35.3         8   1.8e+04      99     298 ..     707     916 ..     680     955 .. 0.62
   3 ?   -0.8   3.8      0.43   9.5e+02     101     178 ..     965    1041 ..     918    1086 .. 0.78
   4 ?    2.1   1.8     0.058   1.3e+02     125     336 ..     988    1121 ..     962    1138 .. 0.50

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 3.5e-08
      AAA_15   1 MkIkkikikNFRslkd.veidlsee.ltvliGkNnsGKSsilealdlFlnnkekkn........................................... 54 
                 M+I +i+i  F+s+   + i+  +e ++ + G N+sGKS+il+a+ + l  +   n                                           
  EEA21031.1   1 MRIVEIIIDGFKSYAVrTVISGWDEsFNSITGLNGSGKSNILDAICFVLGIT---Nmstvraqnlqdliykrgqagvtkasvtivfdnrdkakspigfe 96 
                 9*************986666644446*******************9999977...34478888888999999888888887777775444444444444 PP

      AAA_15  55 ...............kkvikiekedleifeniseskdikIdvef....................................................... 83 
                                                                                                                    
  EEA21031.1  97 eygsisvtrqivlggT---------------------------Skylinghraqqqtvqnlfqsvqlninnpnflimqgritkvlnmkaveilsmieea 168
                 4444444444444441...........................36666666666666666666666666667777777777777788888888888877 PP

      AAA_15  84 ..................................................................................aek.ekakeyektlksk 99 
                                                                                                   + + e +k+ ++tl+++
  EEA21031.1 169 agtrmfedrkekaaktmakkemkvreiegllneeiepkleklrgekrafldfqqtqndverltrlvvahdyvkskdrlklagE-EyEAKKQKIQTLEDS 266
                 77776665555555554444444444444444444444466666666666666666666666666666666666666655531.234555555566555 PP

      AAA_15 100 ekkkadlllkkkesdlkktikdkklklkknelsdekisvekkks.......kkelpkekeeklekekeelkid.kedlkklikkleeslkkeeelknvl 190
                 +++ ++ ++ ++e+d k  + +++ +l k  + +   +  k+ s       +        e ++++ ++ k + k ++k++ + le+ lk +    +v+
  EEA21031.1 267 AARLKN-EIAHLEEDVKRVKAVREKELRKGGKFQALENEVKEHShelvrlaT------VFELKNSSMADEKEKrKASQKSVAE-LEKLLKDKR---KVY 354
                 555444.666666666666666666665554444444444433333222221......1122222222222220222222222.444444444...666 PP

      AAA_15 191 ksaiiklllisakRnvsdedsekkssllgklkekileealqekl..................e 235
                 ++++ k+++ +a+ + ++ + e k++ll +l+  i ++ +qe                     
  EEA21031.1 355 EKLQMKYDTAKAEFDTQTAEVETKEELLQTLQTGIASKEGQENGyqgqlqdarnrasaalteQ 417
                 666666666666666666666666666666666666665555555444444444444433330 PP

  == domain 2  score: -5.8 bits;  conditional E-value: 8
      AAA_15  99 kekkkadlllkkkesdlkktikdkklklkknelsdekisvekkks.kkelpkekeeklekekeelkid......kedlkklikkleeslkkee...... 184
                 ++         kk ++  +++++ +lk+++++l+ + i+ +   s ++  +++ke  ++++k+  + +      ++d+k++ k+++e  + ++      
  EEA21031.1 707 EK---------KKLDAVRSLKQELDLKNHEIKLTEDQINSNSSSSiIQAVKEMKEQIEQLKKDIADAKsryaeaQQDIKRIEKDMKEFDNNKDdklael 796
                 22.........2223333333333333333333333333333333222223333333333333333333322224444444444444444444677777 PP

      AAA_15 185 .....elknvlksaiiklllisakRnvsdedsekkssllgklkekileealqekleeelteklkeiqeklkeidkklaeelk......kilkkkidkik 272
                      +lk++l++++i +++ +++ ++s  +se+  s l+++ e++ e  ++ ++ +e +e lk+ q+ +k++ ++ +++l+       ++++ + +  
  EEA21031.1 797 qtsvdTLKKSLNKNSIAVKTLHKELQASRLESEQAGSDLSAAEEQLAEADNAMQAQLEEIETLKKEQTRIKDAHDIAQAQLEeeqaklTSFDDELGD-- 893
                 788888999999************************************999999999*******************999999777444333333333.. PP

      AAA_15 273 kfnykgkkneeieikddeelplnknG 298
                  ++  + +++ +   ++e+l++ k G
  EEA21031.1 894 -LEQAIRSKNARI--TEESLEAQKLG 916
                 .333333333333..45555555554 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 0.43
      AAA_15  101 kkkadlllkkkesdlkktikdkklklkknelsdekisvekkkskkelpkekeeklekekeelkidkedlkklikklee 178 
                  ++ +   l ++ ++++ ++k+ + k+ +  +s+ek++v  k+ +k     k++ +e+ ++  +++ke l k++ k + 
  EEA21031.1  965 AE-CRSTLRNLTERFQGMKKKINPKVMNMIDSVEKKEVALKNMMKTVVRDKNKIEETIINLDEYKKEALHKTWTKVNA 1041
                  33.334778888889999999999999999999999999999999999999999988888888889999998886554 PP

  == domain 4  score: 2.1 bits;  conditional E-value: 0.058
      AAA_15  125 klkknelsdekisvekkkskkelpkekeeklekekeelkidkedlkklikkleeslkkeeelknvlksaiiklllisakRnvsdedsekkssllgkl 221 
                  k+ +  +s+ek++v                                                                                   
  EEA21031.1  988 KVMNMIDSVEKKEVA---------------------------------------------------------------------------------- 1002
                  222222222222222.................................................................................. PP

      AAA_15  222 kekileealqekleeelteklkeiqeklkeidkklaeelkkilkkkidkik.kfnykgkkneeieik.............................. 287 
                                +++ +   + ++k++e++ +l+e +k+ l k + k++ +f         ++i+                              
  EEA21031.1 1003 -------------LKNMMKTVVRDKNKIEETIINLDEYKKEALHKTWTKVNaDF---------GQIFaellpgsfakldppegkeitdglevkvslg 1077
                  .............33333444444444444444444444444444444442211.........1111222233333455555555566666666666 PP

      AAA_15  288 ddeelplnknGsGvqrllllillileaekkdekeeknvilliEEPEahL 336 
                     +++l++ + G+++l+ l+l  + ++ k     +   ++++E +a L
  EEA21031.1 1078 KVWKQSLTELSGGQRSLIALSLIMALLQFK-----PAPMYILDEVDAAL 1121
                  666677777777777777777777777766.....66666666666655 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.1   1.4e-07   0.00032      24      46 ..      27      49 ..      15      56 .. 0.88

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 1.4e-07
      AAA_29 24 atlltGpsGsGKSTllDAiqalL 46
                +  +tG +GsGKS +lDAi ++L
  EEA21031.1 27 FNSITGLNGSGKSNILDAICFVL 49
                5679***************9998 PP

>> HSBP1  Heat shock factor binding protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.8       2.8   6.2e+03       5      15 ..     125     135 ..     124     140 .. 0.59
   2 ?   -0.0   0.0      0.36   8.1e+02      15      42 ..     483     510 ..     480     516 .. 0.78
   3 ?    8.0   0.3    0.0012       2.6      22      46 ..     740     764 ..     737     768 .. 0.91
   4 ?   -0.6   0.1      0.57   1.3e+03      28      44 ..     792     808 ..     790     811 .. 0.84
   5 ?   11.1   0.5   0.00012      0.27      10      43 ..     970    1003 ..     967    1009 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 2.8
       HSBP1   5 avVenlLqqlq 15 
                 + V+nl+q +q
  EEA21031.1 125 QTVQNLFQSVQ 135
                 45666666665 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 0.36
       HSBP1  15 qdkFqtmsdqilsriDdMssriDdLEks 42 
                 q+  q+   ++ +r D M +r+ +L+ s
  EEA21031.1 483 QSNLQRAIRELRERADGMNRRVANLDFS 510
                 566666677888999*******999866 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.0012
       HSBP1  22 sdqilsriDdMssriDdLEksiadl 46 
                 s++i++ + +M + i++L k iad 
  EEA21031.1 740 SSSIIQAVKEMKEQIEQLKKDIADA 764
                 89*********************97 PP

  == domain 4  score: -0.6 bits;  conditional E-value: 0.57
       HSBP1  28 riDdMssriDdLEksia 44 
                 ++ ++++ +D L ks++
  EEA21031.1 792 KLAELQTSVDTLKKSLN 808
                 78899999999999986 PP

  == domain 5  score: 11.1 bits;  conditional E-value: 0.00012
       HSBP1   10 lLqqlqdkFqtmsdqilsriDdMssriDdLEksi 43  
                  +L +l ++Fq m ++i  ++ +M   ++  E  +
  EEA21031.1  970 TLRNLTERFQGMKKKINPKVMNMIDSVEKKEVAL 1003
                  799********************87777655555 PP

>> VPS11_C  Vacuolar protein sorting protein 11 C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.1   0.3         8   1.8e+04       6      22 ..     332     348 ..     329     349 .. 0.75
   2 ?    3.7   0.2     0.032        72       3      28 ..     739     764 ..     738     768 .. 0.84
   3 ?    8.9   3.3   0.00076       1.7       2      28 ..     854     880 ..     838     884 .. 0.95

  Alignments for each domain:
  == domain 1  score: -4.1 bits;  conditional E-value: 8
     VPS11_C   6 elrraQeesadrhdlFk 22 
                 + + +Q+ +a+   l+k
  EEA21031.1 332 KRKASQKSVAELEKLLK 348
                 66788999999888876 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.032
     VPS11_C   3 tirelrraQeesadrhdlFkaaLees 28 
                 ++  +++a +e++++ +++k+   ++
  EEA21031.1 739 SSSSIIQAVKEMKEQIEQLKKDIADA 764
                 678899*************9987775 PP

  == domain 3  score: 8.9 bits;  conditional E-value: 0.00076
     VPS11_C   2 etirelrraQeesadrhdlFkaaLees 28 
                 e+i+ l+++Q +++d hd+ +a+Lee+
  EEA21031.1 854 EEIETLKKEQTRIKDAHDIAQAQLEEE 880
                 89***********************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1179 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3127  (0.17441); expected 358.6 (0.02)
Passed bias filter:                      586  (0.0326845); expected 358.6 (0.02)
Passed Vit filter:                       184  (0.0102627); expected 17.9 (0.001)
Passed Fwd filter:                       108  (0.00602376); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 2.85u 0.40s 00:00:03.25 Elapsed: 00:00:00.70
# Mc/sec: 5084.23
//
Query:       EEA21032.1  [L=529]
Description: NOT2 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.3e-28   97.1   0.8    2.2e-27   95.7   0.0    1.9  2  NOT2_3_5  NOT2 / NOT3 / NOT5 family


Domain annotation for each model (and alignments):
>> NOT2_3_5  NOT2 / NOT3 / NOT5 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.3      0.12   2.2e+03      14      34 ..     127     148 ..     104     168 .. 0.58
   2 !   95.7   0.0   1.2e-31   2.2e-27      15     131 .]     399     509 ..     382     509 .. 0.82

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.12
    NOT2_3_5  14 kprqyep.klphptsisypqep 34 
                 +p + +p +  ++t+++++q++
  EEA21032.1 127 QPPSSQPpSRTSQTQTHFTQQQ 148
                 2323333355555566664333 PP

  == domain 2  score: 95.7 bits;  conditional E-value: 1.2e-31
    NOT2_3_5  15 prqyepklphptsisypqeplyekle.sakklekldedtLFyiFYysqgtleqllAakeLkkrsWryhkelktWflreeke.epkekteey.ekgsYky 110
                 p +++  +p++    y+  +     +  ++ + +++++tLFyiFY++++++ q+l a+eL  r+Wryhk +++W++r+e++  p  +++ + e+g Y  
  EEA21032.1 399 PLEQDFAIPSC----YNVANV----QpLQSRIPSFSDETLFYIFYSMPRDVLQELVAEELMGRKWRYHKVERCWLTRDENYpGPVDVERGVsERGVYLW 489
                 33333467777....865553....336679***********************************************98877788887777******* PP

    NOT2_3_5 111 FD.yetWlkrrkkdfkleyekL 131
                 +D   +W+k+r ++f l+ye+L
  EEA21032.1 490 WDpA-SWKKIR-REFILRYEDL 509
                 **55.******.*******987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (529 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       763  (0.0425568); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.42
# Mc/sec: 3769.72
//
Query:       EEA21033.1  [L=246]
Description: 50S ribosomal protein L4 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-18   66.5   1.3    3.8e-18   65.4   0.0    2.0  2  MRP-L47   Mitochondrial 39-S ribosomal protein L47 (MRP-L47)


Domain annotation for each model (and alignments):
>> MRP-L47  Mitochondrial 39-S ribosomal protein L47 (MRP-L47)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.4   0.0   2.1e-22   3.8e-18       1      87 []      98     189 ..      98     189 .. 0.86
   2 ?    0.9   0.3     0.028     5e+02      29      60 ..     189     220 ..     189     235 .. 0.62

  Alignments for each domain:
  == domain 1  score: 65.4 bits;  conditional E-value: 2.1e-22
     MRP-L47   1 Leeffdd.kkdl.kseeevkvgraWaaeeLrkksfedLhklwyvllkekNmLlteeeellrkqekmpsperlkk...vkesMeniktVlkeR 87 
                 L+ ff     ++  +e+++  gr+W+++eLr ks+edLh lw+v+ ke+N ++t + e +r +  + + e++++   v+ +  +ik+Vl+eR
  EEA21033.1  98 LWGFFPPdRLPMsTPEYDIAHGRSWSIQELRGKSWEDLHCLWWVCVKERNRISTSNVERERLKAGFGEAELIDRervVRSTQRAIKHVLRER 189
                 677776524466789****************************************999999999987777775333399999*********9 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.028
     MRP-L47  29 rkksfedLhklwyvllkekNmLlteeeellrk 60 
                 r+ ++ed +++w+    e+     ++++l +k
  EEA21033.1 189 RWYAWEDARQIWLKEAEEQWQTEHKKAQLTAK 220
                 67789999999988777765544444444433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (246 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1680  (0.0937029); expected 358.6 (0.02)
Passed bias filter:                      596  (0.0332422); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 1762.73
//
Query:       EEA21034.1  [L=469]
Description: secretory pathway gdp dissociation inhibitor [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   4.1e-193  641.8   0.0   4.8e-193  641.6   0.0    1.0  1  GDI            GDP dissociation inhibitor
     0.0089   16.2   0.0      0.023   14.9   0.0    1.7  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
  ------ inclusion threshold ------
      0.014   15.9   0.4       0.45   11.1   0.2    2.4  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase


Domain annotation for each model (and alignments):
>> GDI  GDP dissociation inhibitor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  641.6   0.0    8e-197  4.8e-193       4     432 ..       7     457 ..       1     461 [. 0.94

  Alignments for each domain:
  == domain 1  score: 641.6 bits;  conditional E-value: 8e-197
                 EECEEEE--SHHHHHHHHHHHHTT--EEEE-SSSSSCGGG-EE-HHHHHHHH-TT...HHHHHHH--GGG--EESS--BEETTSHHHHHHHHTTGGGCS CS
         GDI   4 eydvivlGtGlkecilsGllsvdgkkvlhldrndyyGgesasltleqlyerfkle...ekpeeklGkdrdwnvdlipkfllanGelvkiliktdvtryl 99 
                 eydv+vlGtGl+ec+lsG+lsv+gkkvlh+drnd+yGge+as+++e l++++ +    e+p +k+G+  dwnvdlipk+l++nGel++il+ tdvtryl
  EEA21034.1   7 EYDVVVLGTGLTECVLSGVLSVKGKKVLHIDRNDHYGGEAASVNIETLFKTYGNVrpgEEPWKKYGRVNDWNVDLIPKLLMSNGELTNILVSTDVTRYL 105
                 8*************************************************9966555599*************************************** PP

                 -EEE-SEEEEEE....TCEEEE--SSHHHHHC-TTS-HHHHHHHHHHHHHHHH-BTTBGGGSTT--TTTSBHHHHHHHCT--HHHHHHHHHHTS--SSS CS
         GDI 100 efkaveGsyvyk....egkiakvpanelealaspllglfekrrakkfleyvseyeeddpktyedldlkkatmkevykkfdlsedtkdfiGhalalyrdd 194
                 ef++++Gsyv +    +  +akvp++  eal s+l+glfekrrakkfle+v e++eddp+t+++l+l++ +mk+vy+kf+l+ +t+df+Gh++aly  d
  EEA21034.1 106 EFRQIAGSYVQQgegpKATVAKVPSDAGEALRSSLMGLFEKRRAKKFLEWVGEFKEDDPSTHQGLNLSTCAMKDVYDKFGLEATTRDFVGHSMALYPSD 204
                 ************8888899******************************************************************************** PP

                 GGGGSB..CHHHHHHHHHHHHHHCCCSS-SEEEETT-TTHHHHHHHHHHHHTT-EEETS--ECEEEE-TTS-EEEEEE....TTE........EEEECE CS
         GDI 195 dylkqp..aletleriklyaeslarygkspylyplyGlGelpqgfarlsaiyGGtymlnkpvdevvldedgkvvGvks....eee........vakakk 279
                 +y++    ++e+++ri+ly++s+arygkspy+yplyGlGelpqgfarlsaiyGGtymln++vdev++de+gkv G+k+      +        ++k+ k
  EEA21034.1 205 EYINAKgrVIESINRIRLYVNSMARYGKSPYIYPLYGLGELPQGFARLSAIYGGTYMLNTSVDEVLYDENGKVSGIKAtmkeR-DeagegmkfTTKTTK 302
                 ***87522679*****************************************************************9744321.12334444467999* PP

                 EEE-GGG-CCCEEEEEEEEEEEEEESS--TTSTT-SSEEEEE-GGGCTSSS-EEEEEEEGGGTSS-TT-EEEEEEEE--SS.-HHHHTHHHHHTT-SEC CS
         GDI 280 vicdpsylpekvrkvgkviraicilshpipntddadsvqiiipqkqlgrksdiyvalvssahnvaakgkylaivsttvete.npevelepalellgpie 377
                 +i+dpsy+p+kv+ +g viraicil+hpi +td +ds+q+iipq+q+grk+diy+a+vssahnv++kg+y+aivst+ e+e n + elep+++ lg ie
  EEA21034.1 303 IIADPSYFPNKVKITGYVIRAICILKHPIDKTDGSDSLQLIIPQSQVGRKHDIYIAMVSSAHNVCPKGYYVAIVSTIAESEaNHHLELEPGFQRLGQIE 401
                 *******************************************************************************9637789************* PP

                 EEEEEE.EEEEEESSSSTTTSEEE-----S-SBSHHHHHHHHHHHHHHHSS----- CS
         GDI 378 ekfvki.sdlyepvedgskdnifisksydatshfettvedvkdiykrltGkkldlk 432
                 e+f+     lyep++dg kdn+fisksydatshfett++dv+diy+r  G++l+++
  EEA21034.1 402 ERFMGPpIPLYEPLDDGKKDNVFISKSYDATSHFETTTDDVRDIYERAEGHELVVE 457
                 ****85268*******************************************9986 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   3.8e-06     0.023       1      40 [.      12      51 ..      12      63 .. 0.91

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 3.8e-06
                   EE--SHHHHHHHHHHHCCTEEEEEE-SSSSSSGGG-EECE CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekrdrlGGraasyev 40
                   ++G+Gl+ +v+   L+ +g++vl ++++d+ GG aas+++
     EEA21034.1 12 VLGTGLTECVLSGVLSVKGKKVLHIDRNDHYGGEAASVNI 51
                   79***********************************986 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.2   7.5e-05      0.45       2      47 ..      10      52 ..       9      61 .. 0.84
   2 ?    2.4   0.0     0.039   2.3e+02      56      79 ..     259     283 ..     251     289 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 7.5e-05
                EEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSSTTSSHHHHHHHH CS
   Pyr_redox  2 vvvvGgGyiglElAgalaelgkkVtvversdkllrllDeeaskilq 47
                vvv+G G++ + l g+l+  gkkV  ++r+d+     +e+as +++
  EEA21034.1 10 VVVLGTGLTECVLSGVLSVKGKKVLHIDRNDHYG---GEAASVNIE 52
                8******************************988...555555555 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.039
                 EEECSEEEEEEEEETTS.EEEEEEE CS
   Pyr_redox  56 evllntkveeiegsedg.vesvklk 79 
                 + +lnt+v e+  +e+g v+++k +
  EEA21034.1 259 TYMLNTSVDEVLYDENGkVSGIKAT 283
                 6799*************9**99975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (469 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       340  (0.0189637); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.42
# Mc/sec: 3359.48
//
Query:       EEA21035.1  [L=171]
Description: thioesterase family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.5e-12   45.6   0.0    9.2e-12   45.2   0.0    1.2  1  4HBT      Thioesterase superfamily
    0.00013   22.4   0.2     0.0025   18.1   0.0    2.0  2  4HBT_3    Thioesterase-like superfamily
  ------ inclusion threshold ------
       0.03   14.7   0.0      0.052   13.9   0.0    1.3  1  DUF3662   Protein of unknown function (DUF2662)


Domain annotation for each model (and alignments):
>> 4HBT  Thioesterase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.2   0.0   1.5e-15   9.2e-12       2      77 ..      73     151 ..      72     153 .. 0.95

  Alignments for each domain:
  == domain 1  score: 45.2 bits;  conditional E-value: 1.5e-15
                 SSB-HHHHHHHHHHHHHHHHHHTTST...TEEEEEEEEEEEESS-BBTTCEEEEEEEEEEEESSEEEEEEEEEETTSCE CS
        4HBT   2 GvvhgGvylallDeaagaalrslggr...gilvvvvelsidflrpvrlgdeltvearvlrlgrtsavvevevrdedgrl 77 
                 +++hgG+ ++++D    + ++  g++   +++ v ++l++++lrpv ++ e++v ++v+++g++   ++ e+r+ d+  
  EEA21035.1  73 NNLHGGCAATIIDILTVIPVMAVGKPgvfQYGGVSRNLNVTYLRPVPVHTEIRVVCEVTQIGKRLSLLRAEIRRVDDDA 151
                 689****************9999999999*********************************************99875 PP

>> 4HBT_3  Thioesterase-like superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.3   0.0     0.007        42     130     182 ..      27      95 ..       3     107 .. 0.54
   2 !   18.1   0.0   4.1e-07    0.0025      33      80 ..     106     155 ..      65     170 .. 0.70

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.007
                 E-HHT---S.....................S-EEEEEEEET..TTS.-SSHHHHHHHHTT-.-GGGGTSS CS
      4HBT_3 130 feprpaegg.............kpd.spagpkrvrqWvrlr..egg.epahlaaLaylsDsfpvprvhgl 182
                 +  r a ++             + +  p +++++r +v ++  + +  ++h  ++a + D+++v  v+ +
  EEA21035.1  27 LVRRDANEQrwtidqttkvrleSATqGPPARATFRLFVTPAmtN-AlNNLHGGCAATIIDILTVIPVMAV 95 
                 2222221111222222333322222234457899******9643.35899*99********866666554 PP

  == domain 2  score: 18.1 bits;  conditional E-value: 4.1e-07
                 S.EEEEEEE-S---SE.EEEEEEEEEE--SS-EEEEEEEEETTEEEEEEE CS
      4HBT_3  33 l.hslhvyFlrpgdag.pviyhvervrdGrsfstrtvelsqggrpiftat 80 
                 + ++l v++lrp+++  ++++ +e++  G++ s++++e+++ + +++ ++
  EEA21035.1 106 VsRNLNVTYLRPVPVHtEIRVVCEVTQIGKRLSLLRAEIRRVDDDALCVL 155
                 36899**********************************98655554444 PP

>> DUF3662  Protein of unknown function (DUF2662)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   8.6e-06     0.052      66     105 ..      12      51 ..       9      59 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 8.6e-06
     DUF3662  66 rlasleeelaeeladllaehareqgytlvgpvtVeleede 105
                 ++ ++e+ ++e l+ l+++ a+eq++t+++  +V+le+  
  EEA21035.1  12 EFDEFETGIEEMLQHLVRRDANEQRWTIDQTTKVRLESAT 51 
                 577889999***************************9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (171 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       359  (0.0200234); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.42u 0.25s 00:00:00.67 Elapsed: 00:00:00.42
# Mc/sec: 1215.66
//
Query:       EEA21036.1  [L=701]
Description: origin recognition complex subunit Orc4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.9e-48  162.4   0.0    1.6e-47  161.7   0.0    1.3  1  ORC4_C         Origin recognition complex (ORC) subunit 4 C-t
    5.8e-16   59.3   0.1    2.6e-15   57.2   0.1    2.1  2  AAA_16         AAA ATPase domain
    2.7e-07   30.9   0.0    6.4e-07   29.7   0.0    1.6  1  AAA_22         AAA domain
    3.6e-07   30.2   0.9    8.2e-07   29.1   0.2    1.9  2  NACHT          NACHT domain
    6.5e-07   29.8   0.0      2e-06   28.3   0.0    1.8  1  AAA            ATPase family associated with various cellular
    5.2e-06   25.8   0.0    8.6e-06   25.1   0.0    1.3  1  DUF815         Protein of unknown function (DUF815)
    0.00015   21.8   0.0    0.00028   20.9   0.0    1.4  1  ATPase_2       ATPase domain predominantly from Archaea
     0.0003   20.1   0.1    0.00078   18.8   0.0    1.5  1  KAP_NTPase     KAP family P-loop domain
    0.00046   20.5   0.1    0.00093   19.5   0.1    1.5  1  AAA_19         AAA domain
      0.002   17.4   0.1     0.0034   16.6   0.1    1.3  1  NB-ARC         NB-ARC domain
      0.005   16.6   1.0     0.0093   15.7   0.1    1.9  2  AAA_30         AAA domain
     0.0053   16.1   0.1     0.0091   15.4   0.1    1.3  1  FtsK_SpoIIIE   FtsK/SpoIIIE family
     0.0067   16.2   0.6      0.018   14.8   0.1    1.9  2  AAA_29         P-loop containing region of AAA domain
  ------ inclusion threshold ------
      0.017   15.2   0.1      0.094   12.8   0.1    2.3  1  AAA_14         AAA domain
      0.022   15.3   0.0      0.052   14.1   0.0    1.7  1  ABC_tran       ABC transporter
      0.025   13.8   0.1      0.056   12.6   0.1    1.6  1  PIF1           PIF1-like helicase
      0.039   13.5   0.3      0.091   12.3   0.0    1.7  2  AAA_25         AAA domain
      0.053   12.4   0.0      0.084   11.7   0.0    1.2  1  DUF2791        P-loop Domain of unknown function (DUF2791)
      0.063   12.6   0.4       0.11   11.8   0.4    1.4  1  Gtr1_RagA      Gtr1/RagA G protein conserved region
      0.064   12.4   0.0       0.11   11.7   0.0    1.3  1  G-alpha        G-protein alpha subunit
      0.081   12.4   0.0       0.16   11.4   0.0    1.5  1  AAA_7          P-loop containing dynein motor region
       0.12   12.1   0.0       0.29   10.8   0.0    1.6  1  BAG6           BCL2-associated athanogene 6
       0.16   12.0   0.0        0.3   11.1   0.0    1.4  1  TsaE           Threonylcarbamoyl adenosine biosynthesis prote


Domain annotation for each model (and alignments):
>> ORC4_C  Origin recognition complex (ORC) subunit 4 C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  161.7   0.0   2.1e-50   1.6e-47       3     219 .]     462     689 ..     460     689 .. 0.91

  Alignments for each domain:
  == domain 1  score: 161.7 bits;  conditional E-value: 2.1e-50
      ORC4_C   3 ckelLslpeeesseeasdsa....dakfleaWnksieelledsafqellkrlyyltksvrallnslilpvsalspssp.......kitaesllsalesa 90 
                 c + Ls++ +e ++++   +     +++l+ W++++++l+ed+ f+++l+r++++tksv+++++s++lp+s+l +s++        +t+e ++++++++
  EEA21036.1 462 CLSTLSVEATEIEDSDFGGRkpvkLPQLLDVWKAYLKSLWEDKDFESHLQRIFHQTKSVKEFYSSALLPISNLYHSASdlesdleIPTPEGFATQSLTC 560
                 889999999999766655558999***************************************************887777777667778888888875 PP

      ORC4_C  91 apd......sklslLrsLSeLeLaLLIaaarldeiydtd.........tvNFemaydeYkklakrakvqsssassqssasgalatgarvWgrdvalkaw 174
                 + +      s l+   s ++L+L+LL+aa+rl++ yd+          +++F++ay+eY++l+++ak++       ++a+ga+atg+rvWgrdv ++aw
  EEA21036.1 561 PDPgplpfsSSLTGSTSATSLPLSLLLAATRLTALYDPGsdvansqslALSFPAAYAEYVRLLTSAKAT-------AAAQGAAATGGRVWGRDVSREAW 652
                 555799888777777799************************************************888.......78899****************** PP

      ORC4_C 175 erLisleLllpagagsssessssgggkefrmvrlevsleeikaav 219
                 e+L++++L++          +s +g+ ++ m+r+e+s+ee++++v
  EEA21036.1 653 EKLVNWGLVVSL--------GSRNGTTDGTMFRVEISFEEVADMV 689
                 ***********9........6788*****************9987 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       4.9   3.8e+03      60      98 ..     189     221 ..     168     250 .. 0.75
   2 !   57.2   0.1   3.3e-18   2.6e-15       2     169 ..     258     421 ..     257     422 .. 0.80

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 4.9
      AAA_16  60 cdqlesaipysalaqalareellrqlldeaesaeleawr 98 
                  d++     y+++a +l  e+l+ +++ ++e+a  ++ +
  EEA21036.1 189 MDDS-----YDPVAAQL-HEDLIHDVDGHEETAPSSPLP 221
                 4444.....88888888.459999999987776655554 PP

  == domain 2  score: 57.2 bits;  conditional E-value: 3.3e-18
      AAA_16   2 lvGReeeleqLlsale.rvrsgrpelvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipysalaqalareellrqlldeaesaeleawre 99 
                 l G ++e +++++++e +v +g+++++ll G +G+GK+++v+ +  +l k+     +g+++                  +l    +++++ a++e wr+
  EEA21036.1 258 LKGLDAEYQKVHQLVEqTVTAGEGNSMLLMGSRGSGKTTMVEWIISSLMKK----HKGDFHVV----------------RLNGFFHTDDRLALREIWRQ 336
                 7799************99999999*****************9999999999....67777777................45555566666666666666 PP

      AAA_16 100 kleealaavpelagaeasrllellkrllallsrder...............plvlvlDdlqwadeaslql.laaLlrlles.k.pllv 169
                   +e+ +   e+++++ ++ +++++ llalls++e+                +v++lD+++ + ++++q  l++L++ +++ k pl+v
  EEA21036.1 337 LGRETDT---EDEASKVNSYADTMATLLALLSHPEEllnsadntngittakSVVIILDEFDLFATHPRQTlLYNLFDIAQArKaPLAV 421
                 4444333...555555588888888888888887778888888888888867**************************9998668887 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.7   0.0   8.2e-10   6.4e-07       5     128 ..     281     422 ..     276     429 .. 0.75

  Alignments for each domain:
  == domain 1  score: 29.7 bits;  conditional E-value: 8.2e-10
      AAA_22   5 agilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelka............erlsseellealeqalrarav 91 
                  ++++++G  G+GKTt ++++ ++l +  k++  + +vv+ +    t+ +  lre+ r+lg+e+++              +++ +ll++ e+ l++++ 
  EEA21036.1 281 GNSMLLMGSRGSGKTTMVEWIISSLMK--KHKG-DFHVVRLNGFFHTDDRLALREIWRQLGRETDTedeaskvnsyadTMATLLALLSHPEELLNSADN 376
                 6789********************953..3433.666666666555544444666666666666666666*****999888888888888888888888 PP

      AAA_22  92 ........ielliiDEaqhlr...seealeeLrsllnlsrkgvqliLv 128
                          +++i+DE++ +    ++++l +L +++     + +l + 
  EEA21036.1 377 tngittakSVVIILDEFDLFAthpRQTLLYNLFDIAQ--ARKAPLAVL 422
                 889998889**********987655999999977777..555555555 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.1   0.2   1.1e-09   8.2e-07       3     142 ..     284     437 ..     282     453 .. 0.77
   2 ?   -3.0   0.0       7.8   6.1e+03     106     146 ..     569     609 ..     559     611 .. 0.75

  Alignments for each domain:
  == domain 1  score: 29.1 bits;  conditional E-value: 1.1e-09
                 EEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEE.EEEETTTTTTS-...-HCHHHCCCCTS--SSS-C........CHHHHCCSCCCEE........ CS
       NACHT   3 vilqGeaGsGKTtLlqklalawaegklpqgafklv.Fflslrelsrsgnarsladllfsqlpepaapvse........vwavllelperlL........ 84 
                 ++l G  GsGKTt+++++++ + +++     f +v +  +++++ r  + r + ++l ++ + + ++++             ll++pe lL        
  EEA21036.1 284 MLLMGSRGSGKTTMVEWIISSLMKKHKGD--FHVVrLNGFFHTDDRL-ALREIWRQLGRETDTEDEASKVnsyadtmaTLLALLSHPEELLnsadntng 379
                 7899********************99444..6665144444555554.345667777666655555554488999988777888999999999999999 PP

                 ........EEEE-STT-SS-TCH.........HHHHHCTTTTT--EEEEEEECCCHHHHCTTSSCE CS
       NACHT  85 ........lilDglDelvtdlgqkekqpvrtlLselirkkllpeasllltvrpralrdleeqleea 142
                         +ilD +D ++t+++q       tlL +l+  +  ++a+l +   ++++ d+ e+le+ 
  EEA21036.1 380 ittaksvvIILDEFDLFATHPRQ-------TLLYNLFDIAQARKAPLAVLGLTTKV-DVTETLEKR 437
                 99999999***********9999.......99999999999999998877666666.666666655 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 7.8
                 ...HHHHHCTTTTT--EEEEEEECCCHHHHCTTSSCE..EE CS
       NACHT 106 rtlLselirkkllpeasllltvrpralrdleeqleeaivle 146
                    L++  ++++lp + ll+++r +al d ++ ++ +++l+
  EEA21036.1 569 SSSLTGSTSATSLPLSLLLAATRLTALYDPGSDVANSQSLA 609
                 56677778889999999999999999877777666666655 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.3   0.0   2.6e-09     2e-06       1     126 [.     284     444 ..     284     448 .. 0.79

  Alignments for each domain:
  == domain 1  score: 28.3 bits;  conditional E-value: 2.6e-09
                 EEEESSTTSSHHHHHHHHHHHH......THEEEEEETTTCSSS................................STTHHHHHHHHHHHHHHHTS.... CS
         AAA   1 vllyGppGtGKTllakavakel......gvefleisgsellsk................................yvgesekkirelfkeakeka.... 57 
                 +ll+G  G GKT++++ ++++l      ++++++++g   +++                                ++ +  ++ +el+++a + +    
  EEA21036.1 284 MLLMGSRGSGKTTMVEWIISSLmkkhkgDFHVVRLNGFFHTDDrlalreiwrqlgretdtedeaskvnsyadtmaTLLALLSHPEELLNSADNTNgitt 382
                 89*******************9766644488888888888866899999****************9**9888888555555555555655555557777 PP

                 .TSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTSSSTEEEEEEESS...GGGSTHHHHSTTSSE CS
         AAA  58 .kpsilfiDEidalaksrsgseseeeervvnqLlteldgvkkkeskvivigatnr...pdkldpallrgRfdr 126
                  k +++++DE+d +a++            +  L++ +d  + +++++ v+g t++    ++l++ +  +Rf++
  EEA21036.1 383 aKSVVIILDEFDLFATHP----------RQTLLYNLFDIAQARKAPLAVLGLTTKvdvTETLEKRVK-SRFSH 444
                 566***********9998..........588899999999999999*********444444555555.77765 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1   0.0   1.1e-08   8.6e-06      19      81 ..     247     309 ..     232     334 .. 0.86

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 1.1e-08
      DUF815  19 veevdevklddLvgidkqkealventeqfleglpannvLLwGarGtGKSslvkallneyaeeg 81 
                 +e++ + +l+ L+g+d++ +++ + +eq ++  + n +LL+G+rG+GK ++v  +++++ +++
  EEA21036.1 247 LEKLTRKRLTPLKGLDAEYQKVHQLVEQTVTAGEGNSMLLMGSRGSGKTTMVEWIISSLMKKH 309
                 477888899*******************************************99999887765 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.0   3.6e-07   0.00028      12     151 ..     273     414 ..     268     457 .. 0.74

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 3.6e-07
    ATPase_2  12 eeilerepneiyfiYGpegsGKtaLlkeiienledkdkyviyyialreesiskldefie........eeeekkklekalgiavpkaeleeilkeksklv 102
                 e+ +  ++ + +++ G++gsGKt+++  ii+ l +k+k  + +  l++ + +  +  ++        e++ +++++k+ + a   a+l ++l++  +l+
  EEA21036.1 273 EQTVTAGEGNSMLLMGSRGSGKTTMVEWIISSLMKKHKGDFHVVRLNGFFHTDDRLALReiwrqlgrETDTEDEASKVNSYADTMATLLALLSHPEELL 371
                 66677788888999************************9999999999998888877778888999977777777777766666666656655444442 PP

    ATPase_2 103 fkaielllekikkkgkkiiiiiDelqklidlglngaellvkeLlnlies 151
                   + ++  + i+  +k ++ii+De+           + l+++L+++ + 
  EEA21036.1 372 --NSADNTNGITT-AKSVVIILDEFDLFA---THPRQTLLYNLFDIAQA 414
                 ..22333444544.466*******98777...44568999999887765 PP

>> KAP_NTPase  KAP family P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.0     1e-06   0.00078      16      94 ..     277     354 ..     263     365 .. 0.82

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 1e-06
  KAP_NTPase  16 tlatpivvgLygkWGsGKssllnkledelkefakpvrflfaefnawsfkggddavaellaaLadaleeeygqlatkllr 94 
                 t++++ +  L g  GsGK+++++ ++++l ++  + +f+++++n +  ++   a++e+ ++L ++  +e ++ +++ ++
  EEA21036.1 277 TAGEGNSMLLMGSRGSGKTTMVEWIISSLMKK-HKGDFHVVRLNGFFHTDDRLALREIWRQLGRETDTEDEASKVNSYA 354
                 44788888999999*********988766555.59***************9999****999999999988888777665 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.1   1.2e-06   0.00093       7     125 ..     278     408 ..     273     423 .. 0.66

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 1.2e-06
      AAA_19   7 alkekvllvtaGpGtGKTrvlkhivallvelggvkpeeillvaftg.rAakelrerlaalgae.............atTiHrlalldfddlltealell 91 
                 a + + +l+++  G+GKT++++ i++ l + ++ + + + l  f +      lre  ++lg+e             a+T+  l  l    ll+++ ell
  EEA21036.1 278 AGEGNSMLLMGSRGSGKTTMVEWIISSLMKKHKGDFHVVRLNGFFHtDDRLALREIWRQLGREtdtedeaskvnsyADTMATL--L---ALLSHPEELL 371
                 5677899************************9988644444433220222334555555588855566666666666666666..3...4444556677 PP

      AAA_19  92 eeaeeekklqeee..llivDEfqdvd.elqyrLlkal 125
                 ++a++++ ++ ++  ++i DEf        ++Ll +l
  EEA21036.1 372 NSADNTNGITTAKsvVIILDEFDLFAtHPRQTLLYNL 408
                 7777777776555568888**9877655555565555 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.1   4.3e-06    0.0034       5     100 ..     268     361 ..     264     370 .. 0.76

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 4.3e-06
                 HHHHHHHHHCTTTSCSEEEEEEESTTSSHHHHHHHHCCSHCCCCC.CBTEEEEEEEESXXHHHHHHHXXHHHHHCCCTTSSSS-STTSHHHHHHHHC CS
      NB-ARC   5 vekviekLlekdelqslvvalvGmgGvGKttlakqilnksdeveg.rFdsvawvvvsktdkseeiletilkeLslseddleekeeveslkrklvrlL 100
                 v ++ e+ +  +e +   + l+G  G+GKtt+++ i++++ + ++  F +v      +td+   +  +i+++L+++ d  +e ++v+s ++ +  lL
  EEA21036.1 268 VHQLVEQTVTAGEGN--SMLLMGSRGSGKTTMVEWIISSLMKKHKgDFHVVRLNGFFHTDDRLALR-EIWRQLGRETDTEDEASKVNSYADTMATLL 361
                 556666666556666..799*****************99654444478777776777777766655.5********999999999988777776665 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.1   1.2e-05    0.0093      13     109 ..     276     405 ..     266     425 .. 0.62
   2 ?   -2.2   0.1       3.7   2.9e+03      12      44 ..     621     654 ..     617     668 .. 0.75

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 1.2e-05
      AAA_30  13 lltsgdrvavltGpAGtGKttalkal.reaweaag..grviglAptgkaAkvLa..................eelgieastiakllkrlk......... 81 
                 +++++   ++l G  G+GKtt+++ +   ++++++  ++v+ l       ++La                   +++  a+t+a ll  l          
  EEA21036.1 276 VTAGEGNSMLLMGSRGSGKTTMVEWIiSSLMKKHKgdFHVVRLNGFFHTDDRLAlreiwrqlgretdtedeaSKVNSYADTMATLLALLShpeellnsa 374
                 34445568999*************996667776644755665555555566666556665555553333322233345666666665555999****** PP

      AAA_30  82 ...grarlepgtllivDEagmvdtkqlaall 109
                    +  + +++ ++i DE  + +t+  ++ll
  EEA21036.1 375 dntNGITTAKSVVIILDEFDLFATHPRQTLL 405
                 9773345556688899**9999877655554 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 3.7
      AAA_30  12 alltsgdrvavltGpAGtGKttalkal.reawea 44 
                 +llts + +a+++G+A tG     + + reawe+
  EEA21036.1 621 RLLTSAKATAAAQGAAATGGRVWGRDVsREAWEK 654
                 4677777899999999998777777766777776 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.1   1.2e-05    0.0091      35      68 ..     271     310 ..     242     315 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 1.2e-05
                   GGGS-.......SEEEE--TTSSHHHHHHHHHHHHHTT-- CS
  FtsK_SpoIIIE  35 lkkma......shllvaGatgsGKStalntLilSlattht 68 
                   l++ +      + +l++G+ gsGK+t++  +i Sl+ +h+
    EEA21036.1 271 LVEQTvtagegNSMLLMGSRGSGKTTMVEWIISSLMKKHK 310
                   33333344687889*********************99886 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.1   2.2e-05     0.018      15      50 ..     274     309 ..     268     314 .. 0.75
   2 ?   -2.8   0.1       6.9   5.4e+03       5      11 ..     654     660 ..     654     663 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 2.2e-05
      AAA_29  15 htieidlkgatlltGpsGsGKSTllDAiqalLvpak 50 
                 +t++  + +++ll+G  GsGK+T++  i+  L+ ++
  EEA21036.1 274 QTVTAGEGNSMLLMGSRGSGKTTMVEWIISSLMKKH 309
                 4555554449**************987777776665 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 6.9
      AAA_29   5 qlvNWgt 11 
                 +lvNWg 
  EEA21036.1 654 KLVNWGL 660
                 58***96 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.1   0.00012     0.094       4      35 ..     283     315 ..     280     398 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 0.00012
      AAA_14   4 ilvitGaRrvGKTtllkqlikell.vkkesily 35 
                  ++++G R +GKTt+++ +i++l+  +k ++  
  EEA21036.1 283 SMLLMGSRGSGKTTMVEWIISSLMkKHKGDFHV 315
                 5789****************9998633333333 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   6.7e-05     0.052       6      43 ..     276     314 ..     271     392 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 6.7e-05
                 EEEETTSEEEEEESTTSSHHHHHHHHTT.SS--SEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxx RF
    ABC_tran   6 lklkegekvaivGenGaGKStLlkllag.llkpteGeil 43 
                 ++  eg+ + ++G+ G+GK+t+++ ++  l+k+ +G+ +
  EEA21036.1 276 VTAGEGNSMLLMGSRGSGKTTMVEWIISsLMKKHKGDFH 314
                 67778999***************9766515566777764 PP

>> PIF1  PIF1-like helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.1   7.2e-05     0.056       2      51 ..     261     310 ..     260     317 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 7.2e-05
                 --HHHHHHHHHH......HCTS-EEEEESTTSSCHHHHHHHHHHCHCTCC CS
        PIF1   2 LneeQkkvfdaiieavlnekgklfFvtGsgGtgKtflwkallkklrsegk 51 
                 L +e +kv + + ++v++ +g+++ + Gs G+gKt + + ++++l +++k
  EEA21036.1 261 LDAEYQKVHQLVEQTVTAGEGNSMLLMGSRGSGKTTMVEWIISSLMKKHK 310
                 67788999999*999****************************9988765 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.1       7.3   5.7e+03      76     100 ..      69      92 ..      61     110 .. 0.77
   2 ?   12.3   0.0   0.00012     0.091      10      74 ..     256     320 ..     248     399 .. 0.61

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 7.3
      AAA_25  76 yvsaEdsedelrrRlravgealrdd 100
                 + +aEd+e +  r lra g++++++
  EEA21036.1  69 FNDAEDNE-TSSRSLRASGRQRKAP 92 
                 56789998.9999999999887443 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 0.00012
      AAA_25  10 vsvadlaapppprrwlvkg..llpagelallaGapgtGKttlaldlalavatGkpwlgpvapeqgkV 74 
                 ++  +l+a+ +++ +lv+      +g   ll+G +g+GKtt++  +  ++++ ++  g++++ + + 
  EEA21036.1 256 TPLKGLDAEYQKVHQLVEQtvTAGEGNSMLLMGSRGSGKTTMVEWIISSLMKKHK--GDFHVVRLNG 320
                 56778999999999999983344567799*************9888888886653..4555555555 PP

>> DUF2791  P-loop Domain of unknown function (DUF2791)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00011     0.084      29     112 ..     260     344 ..     258     352 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00011
     DUF2791  29 Grereiealledle.rvaeggaafrfirGeYGsGKtFllqllreralerg...fvva..eadlsperrLhgtkgqlealYrelvenlstk 112
                 G+++e +++++ +e +v++g+++  +++G  GsGKt +++++ +  ++++   f v+  +  + ++ rL+     l++++r+l ++  t+
  EEA21036.1 260 GLDAEYQKVHQLVEqTVTAGEGNSMLLMGSRGSGKTTMVEWIISSLMKKHkgdFHVVrlNGFFHTDDRLA-----LREIWRQLGRETDTE 344
                 7788888888888625999***********************9999987422243330033455777776.....666666666665555 PP

>> Gtr1_RagA  Gtr1/RagA G protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.4   0.00014      0.11       2      24 ..     284     306 ..     283     314 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00014
   Gtr1_RagA   2 vLLmGksgsGKtsmrsiiFdnyl 24 
                 +LLmG +gsGKt+m + i + ++
  EEA21036.1 284 MLLMGSRGSGKTTMVEWIISSLM 306
                 79************999887765 PP

>> G-alpha  G-protein alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00014      0.11      24     160 ..     282     521 ..     259     541 .. 0.66

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00014
                 EEEEEEESTTSSHHHHHHHHHHHCS----HHHH.HCCHHHHHHHHHHHHHHHHHHHHHTT.......HHHC-SS-SCCCS-HCHHHH............ CS
     G-alpha  24 vkllllGqseSGKsTilkqlkllykkgfseeel.atwraviqlnivrsiktilealesleselsesfelqelkerldplkkveasliaklssateee.. 119
                  ++ll+G+ +SGK+T+++ +    +k+++ +     ++ + ++    +++ i ++l +++++ +e ++ +++ + ++ l+++ +   + l+sa + +  
  EEA21036.1 282 NSMLLMGSRGSGKTTMVEWIISSLMKKHKGDFHvVRLNGFFHTDDRLALREIWRQLGRETDTEDEASKVNSYADTMATLLALLSHPEELLNSADNTNgi 380
                 379*************99998555555554433244677888888888999999999987777777777777777777777776665555555554466 PP

                 .............................................HHCCHHC-HCHHH......................................... CS
     G-alpha 120 .............................................qeiefnpraevge......................................... 132
                                                              +           +                                         
  EEA21036.1 381 ttaksvviildefdlfathprqtllynlfdiaqarkaplavlgltT-----------Kvdvtetlekrvksrfshryvylplarsfeafsdsclstlsv 468
                 6777666666666555555555555555444444444444444441...........044444444455556666666688888888888888888888 PP

                 ...........................HHHHHCCSHHHHHHHCCGCCTT--TTHH CS
     G-alpha 133 ...........................dikaLwndpgiqelyerrnkiklednae 160
                                            ++k+Lw+d+ + + ++r   ++   +++
  EEA21036.1 469 eateiedsdfggrkpvklpqlldvwkaYLKSLWEDKDFESHLQRI--FHQTKSVK 521
                 888888899999999999999999999999999999666666655..33333444 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00021      0.16      32      60 ..     280     308 ..     263     327 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00021
       AAA_7  32 nkkpvllvGptGtGKtviikdllkkldke 60 
                 +++++ll+G+ G+GKt++++ ++++l k+
  EEA21036.1 280 EGNSMLLMGSRGSGKTTMVEWIISSLMKK 308
                 5689***************9987777643 PP

>> BAG6  BCL2-associated athanogene 6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00037      0.29      21      78 ..     495     551 ..     489     580 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00037
        BAG6  21 ryieileedptfeesdntegreeaqrildrvsEalhllshalhalSDlrldLsqpppR 78 
                 +y + l ed +fe +  ++  +++ ++ +  s al  +s+ +h+ SDl  dL+ p+p 
  EEA21036.1 495 AYLKSLWEDKDFESHL-QRIFHQTKSVKEFYSSALLPISNLYHSASDLESDLEIPTPE 551
                 6888889999999998.77799999999999************************996 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00039       0.3       8      44 ..     269     306 ..     262     325 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00039
                 HHHHHHHHHCH....TEEEEEEESTTSSHHHHHHHHHHHTT CS
        TsaE   8 ealgkklakal....gdvilLeGdLGaGKTtlvrglakalg 44 
                 ++l ++    +    g+ +lL G  G+GKTt+v  ++++l 
  EEA21036.1 269 HQLVEQT---VtageGNSMLLMGSRGSGKTTMVEWIISSLM 306
                 3333333...23446777****************9999884 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (701 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       828  (0.0461822); expected 358.6 (0.02)
Passed bias filter:                      497  (0.0277205); expected 358.6 (0.02)
Passed Vit filter:                        92  (0.00513135); expected 17.9 (0.001)
Passed Fwd filter:                        24  (0.00133861); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              23  [number of targets reported over threshold]
# CPU time: 0.75u 0.33s 00:00:01.08 Elapsed: 00:00:00.49
# Mc/sec: 4345.93
//
Query:       EEA21037.1  [L=667]
Description: developmental regulator FlbA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.5e-33  115.5   0.0    3.8e-33  114.3   0.0    1.7  1  RGS           Regulator of G protein signaling domain
      1e-25   89.6   0.0    7.3e-19   67.6   0.0    3.4  3  DEP           Domain found in Dishevelled, Egl-10, and Plecks
     0.0035   17.4   0.0        1.1    9.3   0.0    2.4  2  Replic_Relax  Replication-relaxation


Domain annotation for each model (and alignments):
>> RGS  Regulator of G protein signaling domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.3   0.0   6.3e-37   3.8e-33       1     116 [.     493     632 ..     493     634 .. 0.98

  Alignments for each domain:
  == domain 1  score: 114.3 bits;  conditional E-value: 6.3e-37
                 -HHHHHTSHHHHHHHHHHHHHTTCTHHHHHHHHHHHHHTS.............SHHHHHHHHHHHHHHHHTSTTSTTSSTS-HHHHHHHHHHHCSS... CS
         RGS   1 sleslledqpgrslFreFlesefseenlsFwlaveefkka.............keqeelkkkakeIyneylapsspkelnidkklreelekrleke... 83 
                 +l+++l+d+++r lFreFl+ + +eenlsF+l+v+ef +              ++ +e++++a+ +yn++lap+sp+elni++ lr++l++r++k+   
  EEA21037.1 493 RLNHILHDPALRLLFREFLRYSLCEENLSFYLDVSEFTSHyhrleksgslnkiETVRETLAAAYGLYNAFLAPGSPCELNIEHGLRNSLASRMTKAvgd 591
                 689***********************************************999999999999************************************* PP

                 ........STTTTTTHHHHHHHHHHHHHHHHHHHHTSHHHH CS
         RGS  84 ........qpsrklfeeaqeevfellekdsypkFlkselyl 116
                         q+  +lfe aq++vf+l+++ds+pkF+++++y+
  EEA21037.1 592 desmikslQEVVDLFELAQTSVFKLMSSDSVPKFVRDPKYS 632
                 ****************************************6 PP

>> DEP  Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.8   0.0    0.0012         7       2      25 ..     195     218 ..     194     222 .. 0.91
   2 !   11.3   0.0   4.7e-05      0.28      36      71 ..     253     288 ..     241     289 .. 0.87
   3 !   67.6   0.0   1.2e-22   7.3e-19       1      71 [.     379     459 ..     379     460 .. 0.97

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0012
                 S-SCEEECTTEEESSE-HHHHHHH CS
         DEP   2 vklkdrrkhlktypncftGseavd 25 
                 +kl ++r++++ ++++ft  ea+ 
  EEA21037.1 195 LKLDTHRVRFTRFEHTFTSDEAIN 218
                 6899*****************986 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 4.7e-05
                 HHHHHHHHHHHHHCTSCECSSSSHCC--SSSSS-EE CS
         DEP  36 reeAvalgqlLldqgliehvedkhqeFrdskqafYq 71 
                  e A +++q++ d ++ie v+++++ F + k  +Yq
  EEA21037.1 253 KEMARSVCQRFADARFIESVDGRGNSFFPMKGGLYQ 288
                 5899*********************99888888888 PP

  == domain 3  score: 67.6 bits;  conditional E-value: 1.2e-22
                 SS-SCEEECT.TEEESSE-HHHHHHHHHHHHTSSSSHHHHHHHHHHHHHCTSCECSSSSHCC.........--SSSSS-EE CS
         DEP   1 gvklkdrrkh.lktypncftGseavdWLldnldiedreeAvalgqlLldqgliehvedkhqe.........FrdskqafYq 71 
                 gvk++++rk   k + n+ftG++avdWL+d+ ++ dr+e+  ++ l++++gli+ v++++ +         F+++k+a+Y 
  EEA21037.1 379 GVKMAKERKIgDKFFANTFTGKAAVDWLMDCSTTNDRRETCLIAALFIKHGLITSVQEDRPYaaqeptavdFQPTKHAIYT 459
                 899999999989********************************************************************6 PP

>> Replic_Relax  Replication-relaxation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.6   0.0    0.0025        15      26      93 ..     255     320 ..     238     329 .. 0.63
   2 !    9.3   0.0   0.00018       1.1      54      99 ..     453     499 ..     417     516 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0025
  Replic_Relax  26 tarrrLarLrelgllsrlrkrvggarg...gsepyvYaLtpkGarllaaqra.epeprskrdrrereassrf 93 
                    ar++ +r+++ +++++++ r    ++     ++  Y+LtpkG ++l  qr  + ++ ++r   e + s+r+
    EEA21037.1 255 MARSVCQRFADARFIESVDGR----GNsffPMKGGLYQLTPKGINIL--QRFcQRNGITARHVMEVLESPRN 320
                   367777777777777776666....33233567779***********..55564444444445566666655 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.00018
  Replic_Relax  54 sepyvYaLtpkGarllaaqra.epeprskrdrrereassrflpHtla 99 
                   +++++Y+ t++G+r+    ++ + +  ++  r +r  ++++l+H+l+
    EEA21037.1 453 TKHAIYTVTEHGQRVCGWIAReKSSVSQYDGRGARDSNNARLNHILH 499
                   5799************666665666699999**************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (667 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       579  (0.032294); expected 358.6 (0.02)
Passed bias filter:                      466  (0.0259914); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.68u 0.29s 00:00:00.97 Elapsed: 00:00:00.50
# Mc/sec: 4049.47
//
Query:       EEA21038.1  [L=472]
Description: Pol II transcription elongation factor subunit Cdc73, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-53  179.5   0.0    5.9e-53  178.8   0.0    1.4  1  CDC73_C   RNA pol II accessory factor, Cdc73 family, C-termin


Domain annotation for each model (and alignments):
>> CDC73_C  RNA pol II accessory factor, Cdc73 family, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  178.8   0.0   3.3e-57   5.9e-53       1     156 [.     280     463 ..     280     464 .. 0.96

  Alignments for each domain:
  == domain 1  score: 178.8 bits;  conditional E-value: 3.3e-57
     CDC73_C   1 rkkkPiIlvpssasslltlsnvksfledgkyvppdekkkeaskaenevsisrklkkiad..................skkvrflvvdspekltkedWer 81 
                 r+++PiIl+++sass ++lsn+k fl+dg++vppd+++ ++++++n+  i+r+  +i +                  ++++rf++ ds++++++++W+r
  EEA21038.1 280 RRPDPIILLSPSASSPIRLSNIKAFLQDGVFVPPDHPTLASHTTSNMQIITRQ-TRIGNaagsqggsggaggaaptnRRPTRFILADSTANFKPDYWQR 377
                 589**************************************999999999993.33444689******************************99***** PP

     CDC73_C  82 VvAVfvtgqewqfksykwsepaelFkkvkgvyvkyeeeevpeevkgwn..Vkslqlsr.........skRhrDravveefwealee 156
                 +vAVf+tgq+wqfk+ykws+p+elF+++ g+yv++++e+vp+++k+w+  V+++ l r         s R+ Dr++ve++w+ +e+
  EEA21038.1 378 LVAVFTTGQAWQFKTYKWSNPPELFRHAAGIYVGMSGEHVPNQIKDWGrgVSTFTLARwdekkgvdgSGRWLDREIVEHIWDVIEN 463
                 ************************************************************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (472 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       537  (0.0299515); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.50
# Mc/sec: 2859.98
//
Query:       EEA21039.1  [L=132]
Description: hypothetical protein PMAA_048420 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
     0.0034   17.3   2.6       0.07   13.1   2.6    2.2  1  DUF3819          Domain of unknown function (DUF3819)
  ------ inclusion threshold ------
      0.014   15.1   3.0       0.26   10.9   0.7    2.4  2  DUF5314          Family of unknown function (DUF5314)
      0.031   14.4   0.0      0.046   13.8   0.0    1.4  1  Abhydrolase_4    TAP-like protein
      0.033   14.5   0.6      0.055   13.8   0.6    1.4  1  Phage_T7_Capsid  Phage T7 capsid assembly protein
      0.039   14.0   0.9      0.085   12.9   0.9    1.6  1  Spo0A_C          Sporulation initiation factor Spo0A C termin
      0.044   14.0   4.1       0.27   11.4   1.1    2.5  2  SSPI             Small, acid-soluble spore protein I
      0.079   12.6   1.2       0.15   11.7   0.7    1.6  2  EcsC             EcsC protein family
      0.091   13.0   2.5        4.8    7.5   0.7    3.1  2  TonB_2           TonB C terminal
       0.12   12.3   1.1       0.18   11.7   1.1    1.2  1  Dak2             DAK2 domain
       0.14   12.6   4.7        1.9    8.9   2.9    2.6  3  DNTTIP1_dimer    DNTTIP1 dimerisation domain
       0.16   12.0   4.2       0.34   10.9   4.2    1.9  1  YpjP             YpjP-like protein
       0.16   11.3   0.7       0.56    9.6   0.5    1.7  2  SecD_SecF        Protein export membrane protein
       0.19   11.5   3.1       0.22   11.3   3.1    1.3  1  DUF445           Protein of unknown function (DUF445)
       0.35   10.8   5.1       0.21   11.5   3.1    1.6  1  ARGLU            Arginine and glutamate-rich 1
       0.41   11.0   3.1        3.9    7.9   3.1    2.2  1  Trns_repr_metal  Metal-sensitive transcriptional repressor
       0.47   10.7   8.2        7.8    6.8   0.3    3.2  2  DUF4355          Domain of unknown function (DUF4355)
       0.77   10.1   4.1        4.6    7.6   0.5    2.8  3  Sec3_C_2         Sec3 exocyst complex subunit
        1.6    9.9   4.9        1.3   10.1   2.3    2.2  2  RNase_J_C        Ribonuclease J C-terminal domain
        2.4    8.2   5.0         19    5.4   0.4    2.7  2  Ribosomal_S5     Ribosomal protein S5, N-terminal domain


Domain annotation for each model (and alignments):
>> DUF3819  Domain of unknown function (DUF3819)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.1   2.6   7.4e-05      0.07       5      41 ..      16      53 ..      12      74 .. 0.74

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 7.4e-05
                HHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHH CS
     DUF3819  5 klvqlaierairEiiqpvversvtiAvi.tteelvkKD 41
                k++ +a+e+ai++ iq  ver v+ Av  + e+ vkK 
  EEA21039.1 16 KAFDKAVENAIEDTIQSTVERTVESAVEkAVEKTVKKA 53
                68999*******************99952566677765 PP

>> DUF5314  Family of unknown function (DUF5314)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.7   0.00028      0.26      67     102 ..      10      45 ..       2      50 .. 0.82
   2 ?    8.8   0.3    0.0012       1.2      59     102 ..      34      77 ..      33     119 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00028
     DUF5314  67 qkksvlstldtaLiklIlksvskevkikieeyfqnh 102
                 + + +++ +d+a+ + I+ +++ +v+ ++e+ ++++
  EEA21039.1  10 INEAIIKAFDKAVENAIEDTIQSTVERTVESAVEKA 45 
                 5678999*****************999999877665 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0012
     DUF5314  59 veagltdaqkksvlstldtaLiklIlksvskevkikieeyfqnh 102
                 ve+ + +a +k v +t  +a+   ++ sv+k v++ +  y+  +
  EEA21039.1  34 VERTVESAVEKAVEKTVKKAIHCSVEDSVEKAVEKPMTRYLDRS 77 
                 56777788888888888888888888888888888888887655 PP

>> Abhydrolase_4  TAP-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   4.9e-05     0.046      54      98 ..      36      81 ..      19      92 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 4.9e-05
  Abhydrolase_4 54 kklakalggavlvtvegeGHgala.agntCvdkavdaYLltGelpa 98
                   +++ +a ++av  tv+++ H++++ + +++v+k++++YL++ ++pa
     EEA21039.1 36 RTVESAVEKAVEKTVKKAIHCSVEdSVEKAVEKPMTRYLDRSHVPA 81
                   6677888999999***********9*******************98 PP

>> Phage_T7_Capsid  Phage T7 capsid assembly protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.6   5.8e-05     0.055      50     114 ..      20      86 ..       3      96 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 5.8e-05
  Phage_T7_Capsid  50 qailshleaenkdaae.sleaalerrDlatvkaiinl.ageslakkfGkkpkrsvtkrakPakpkaa 114
                      +a+ +++e + ++++e ++e+a+e+   +tvk  i    + s +k++ k+ +r + ++ +Pa+p   
       EEA21039.1  20 KAVENAIEDTIQSTVErTVESAVEKAVEKTVKKAIHCsVEDSVEKAVEKPMTRYLDRSHVPASPYLI 86 
                      35777888777776552788999999889998766651567999******************99754 PP

>> Spo0A_C  Sporulation initiation factor Spo0A C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.9   9.1e-05     0.085      35      92 ..      12      70 ..       2      76 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 9.1e-05
     Spo0A_C 35 esitkelypevAkkyk.ttpsrVeraIrhaIevaWekgnkekleelfgysinsekgkPt 92
                e+i+k   ++v +  + t +s+Ver +  a+e+a ek  k++++  ++ s+++  +kP 
  EEA21039.1 12 EAIIKAFDKAVENAIEdTIQSTVERTVESAVEKAVEKTVKKAIHCSVEDSVEKAVEKPM 70
                5566666666666665266899***************9999999999999999998886 PP

>> SSPI  Small, acid-soluble spore protein I
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   1.1   0.00028      0.27       2      33 ..       9      40 ..       8      43 .. 0.90
   2 ?    3.5   0.1     0.084        79       8      33 ..      43      68 ..      38      71 .. 0.64

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00028
        SSPI  2 diRkaiiqnlkgsskeeleetIedaiqskeEk 33
                +i +aii+ + ++ ++ +e+tI++++++  E 
  EEA21039.1  9 QINEAIIKAFDKAVENAIEDTIQSTVERTVES 40
                6899**********************988776 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.084
        SSPI  8 iqnlkgsskeeleetIedaiqskeEk 33
                 + +++  k+ ++ ++ed++++  Ek
  EEA21039.1 43 EKAVEKTVKKAIHCSVEDSVEKAVEK 68
                45556666677777777777776666 PP

>> EcsC  EcsC protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.7   0.00016      0.15      19      78 ..      13      72 ..       4      98 .. 0.73
   2 ?   -0.7   0.0         1   9.5e+02     179     214 ..      91     122 ..      76     124 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00016
        EcsC 19 sfleklskklqeklnaliPekvqekitkaieealeavleggeylvekkenkesiedlael 78
                +++++  k+++++++++i + v++++++a+e+a+e++++++ + + ++++ + +e++   
  EEA21039.1 13 AIIKAFDKAVENAIEDTIQSTVERTVESAVEKAVEKTVKKAIHCSVEDSVEKAVEKPMTR 72
                566777788888888888888888888888888888888877777777776666655554 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 1
        EcsC 179 eqvesqesgwleelikeiakelrdqvdkkkllqliP 214
                 ++++++e++    ++ ei ++ rd++  k + + +P
  EEA21039.1  91 TNQNISEAD----VVSEIPETQRDSMEVKTVTEDVP 122
                 232444444....48899999999998888888887 PP

>> TonB_2  TonB C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   0.7    0.0051       4.8      51      65 ..      15      29 ..       6      60 .. 0.85
   2 ?    2.2   0.1      0.23   2.2e+02      47      64 ..      51      68 ..      48      94 .. 0.71

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0051
      TonB_2 51 neafDkavkrAieka 65
                 +afDkav++Aie++
  EEA21039.1 15 IKAFDKAVENAIEDT 29
                589*********954 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.23
      TonB_2 47 ksSgneafDkavkrAiek 64
                k+  +  ++++v++A+ek
  EEA21039.1 51 KKAIHCSVEDSVEKAVEK 68
                566666778999999994 PP

>> Dak2  DAK2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   1.1   0.00019      0.18      73     129 ..      11      68 ..       2      72 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00019
                 --.HHHHHHHHHHHHHHHH---TTSSSTHHHHHHHHHHHHT...........T---HH CS
        Dak2  73 ed.laaalkaaleaiqavgkarpgdkTmlDvlrpavealekakdgedlkealekaaka 129
                 ++ + +a+++a+e+  + +   ++++T+  ++++ave+  k+  + ++++ +eka+++
  EEA21039.1  11 NEaIIKAFDKAVENAIEDTIQSTVERTVESAVEKAVEKTVKKAIHCSVEDSVEKAVEK 68 
                 33388888888855555558889**************999944479999999999975 PP

>> DNTTIP1_dimer  DNTTIP1 dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   2.9     0.002       1.9      14      62 ..       3      49 ..       1      56 [. 0.83
   2 ?    4.8   0.0     0.037        35       9      35 ..      29      55 ..      27      81 .. 0.64
   3 ?    2.9   0.0      0.15   1.4e+02      11      37 ..      59      85 ..      54     116 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.002
  DNTTIP1_dimer 14 inkevdevikkylrkvfkpAveNireNlgeevvteadvqklcrsiLeea 62
                   +n++v ++ +  + k f +AveN+ e + + + +e +v+ ++ ++ e++
     EEA21039.1  3 VNNAVVQINEAII-KAFDKAVENAIEDTIQ-STVERTVESAVEKAVEKT 49
                   7899999999999.************9997.667888888888887765 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.037
  DNTTIP1_dimer  9 vlQpainkevdevikkylrkvfkpAve 35
                   ++Q+ +++ v+  ++k ++k+ k+A++
     EEA21039.1 29 TIQSTVERTVESAVEKAVEKTVKKAIH 55
                   567777777777777777777776664 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.15
  DNTTIP1_dimer 11 QpainkevdevikkylrkvfkpAveNi 37
                     +++k+v++ + +yl  +  pA   +
     EEA21039.1 59 EDSVEKAVEKPMTRYLDRSHVPASPYL 85
                   567889999999999988888886554 PP

>> YpjP  YpjP-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   4.2   0.00036      0.34       9      65 ..       5      60 ..       1     124 [. 0.78

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00036
        YpjP  9 llleeaeeqsllKlGkkiaekiedefeeeilpkieevieellekveeekleeleise 65
                +++ + +e  ++ + k++++ ied ++++++  +e+++e+ +ek+ ++++ + ++++
  EEA21039.1  5 NAVVQINEAIIKAFDKAVENAIEDTIQSTVERTVESAVEKAVEKTVKKAI-HCSVED 60
                55666677777778888888888888888888888888887777544443.444444 PP

>> SecD_SecF  Protein export membrane protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.5   0.00059      0.56     107     140 ..       9      42 ..       2      50 .. 0.86
   2 ?    0.0   0.0       0.5   4.7e+02     116     135 ..      46      65 ..      40      78 .. 0.44

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00059
                 HHHHHHHH--SS-HHHHHHHHHHHHHHHHHHTTH CS
   SecD_SecF 107 rvrenlrkkkratlkeiinlslnqtLtrtiltsl 140
                 ++ e + k  ++ ++++i++ +++t+ rt+   +
  EEA21039.1   9 QINEAIIKAFDKAVENAIEDTIQSTVERTVESAV 42 
                 689999***********************98776 PP

  == domain 2  score: 0.0 bits;  conditional E-value: 0.5
                 -SS-HHHHHHHHHHHHHHHH CS
   SecD_SecF 116 kratlkeiinlslnqtLtrt 135
                  ++t+k++i  s+++ + ++
  EEA21039.1  46 VEKTVKKAIHCSVEDSVEKA 65 
                 33333333333333333333 PP

>> DUF445  Protein of unknown function (DUF445)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   3.1   0.00023      0.22      90     339 ..      19      51 ..       2     128 .. 0.46

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00023
      DUF445  90 eellkeiledlddesikellkknlkkkleevipepllgkllellleeerhkkllddlldriknllkdeevkekikelidelieeesgklvlesivsmfl 188
                  +++++++ed++++ +++ ++++++                                                                          
  EEA21039.1  19 DKAVENAIEDTIQSTVERTVESAVE-------------------------------------------------------------------------- 43 
                 1222222222222222222222222.......................................................................... PP

      DUF445 189 reltsilekvksdpdhllreeedkkvreliadllndpelaakveklkkkklsdlevqeyeealwealkdlllkdlneeesllrerisklleklgeklae 287
                                                                                                                    
  EEA21039.1   - ---------------------------------------------------------------------------------------------------   -
                 ................................................................................................... PP

      DUF445 288 dpklreklnkflenaaakvlekyrldiskiveetvnafdaeeleelIelivg 339
                                                             +++e+ v+
  EEA21039.1  44 --------------------------------------------KAVEKTVK 51 
                 ............................................11111111 PP

>> ARGLU  Arginine and glutamate-rich 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   3.1   0.00022      0.21       8      50 ..      26      69 ..      10      90 .. 0.63

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00022
       ARGLU  8 ieeevarRveeavakrVeeelekr.keeiekeverrveearkkm 50
                ie+ ++  ve+ v++ Ve+ +ek  k++i   ve  ve+a +k 
  EEA21039.1 26 IEDTIQSTVERTVESAVEKAVEKTvKKAIHCSVEDSVEKAVEKP 69
                55555444555554444444443213667777777777665554 PP

>> Trns_repr_metal  Metal-sensitive transcriptional repressor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   3.1    0.0041       3.9      36      70 ..      11      48 ..       4     104 .. 0.74

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0041
                     HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH...HHHHH CS
  Trns_repr_metal 36 laAvrsalnkvglelledhlkhcvaeaiee...ekiee 70
                       A+ +a +k+ +  +ed +++ v++++e+   +++e+
       EEA21039.1 11 NEAIIKAFDKAVENAIEDTIQSTVERTVESaveKAVEK 48
                     46777777777777777777777775554433322222 PP

>> DUF4355  Domain of unknown function (DUF4355)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.3    0.0083       7.8     105     124 ..      12      31 ..       3      32 .. 0.86
   2 ?    5.2   2.9     0.025        24       4      53 ..      41     115 ..      31     130 .. 0.64

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0083
     DUF4355 105 etfkelfnkavekaveeklk 124
                 e++ ++f+kave+a+e+ ++
  EEA21039.1  12 EAIIKAFDKAVENAIEDTIQ 31 
                 78999*********999875 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.025
     DUF4355   4 ytqsevdkivakalet.kknklekeledei........................kkeakklakmnaeekaeyele 53 
                  +++ v k+v+ka++   + + ek++e+ +                        ++ea  + ++ +++++  e++
  EEA21039.1  41 AVEKAVEKTVKKAIHCsVEDSVEKAVEKPMtryldrshvpaspylieqhdtnqnISEADVVSEIPETQRDSMEVK 115
                 445556666666666666666666666666666666666666666666666666666666666666666666655 PP

>> Sec3_C_2  Sec3 exocyst complex subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   0.5    0.0049       4.6      12      44 ..      12      44 ..       6      61 .. 0.69
   2 ?    4.3   0.1     0.055        52      13      36 ..      44      68 ..      37      79 .. 0.53
   3 ?    0.8   0.1      0.68   6.4e+02      25      49 ..      94     119 ..      85     125 .. 0.67

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0049
    Sec3_C_2 12 edaikdvlkelefsldeaiiesveelaeekiel 44
                e  ik   k +e++++++i+++ve  +e  +e 
  EEA21039.1 12 EAIIKAFDKAVENAIEDTIQSTVERTVESAVEK 44
                556777788888888888888888887776653 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.055
    Sec3_C_2 13 daikd.vlkelefsldeaiiesvee 36
                +a+++ v+k +  s+++++ ++ve+
  EEA21039.1 44 KAVEKtVKKAIHCSVEDSVEKAVEK 68
                3333313334445555555555554 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.68
    Sec3_C_2  25 sldea.iiesveelaeekielkevkd 49 
                  + ea +++++ e  ++ +e+k v +
  EEA21039.1  94 NISEAdVVSEIPETQRDSMEVKTVTE 119
                 44443377888888888898888865 PP

>> RNase_J_C  Ribonuclease J C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   2.3    0.0014       1.3      13      60 ..       9      54 ..       6      77 .. 0.76
   2 ?   -1.4   0.0       5.3     5e+03      43      51 ..      99     107 ..      85     127 .. 0.51

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.0014
   RNase_J_C 13 keseeLieeakkvvretieealeekesdwnelkrkirealkkflykkt 60
                + +e +i++  k+v+++ie+++++  + ++++++++ +a++k ++k +
  EEA21039.1  9 QINEAIIKAFDKAVENAIEDTIQS--TVERTVESAVEKAVEKTVKKAI 54
                668899999999999999999887..4555566666666666655544 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 5.3
   RNase_J_C  43 elkrkirea 51 
                 ++ ++i e+
  EEA21039.1  99 DVVSEIPET 107
                 333333333 PP

>> Ribosomal_S5  Ribosomal protein S5, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   0.4      0.02        19      45      62 ..       9      26 ..       5      27 .. 0.85
   2 ?    4.1   0.5     0.048        45      44      62 ..      36      54 ..      32      69 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.02
                  SHHHHHHHHHHHHHHTEE CS
  Ribosomal_S5 45 evatAirkAiekAkknlv 62
                  ++++Ai kA +kA+ n +
    EEA21039.1  9 QINEAIIKAFDKAVENAI 26
                  5789*********99976 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.048
                  SSHHHHHHHHHHHHHHTEE CS
  Ribosomal_S5 44 kevatAirkAiekAkknlv 62
                  ++v+ A++kA+ek +k+ +
    EEA21039.1 36 RTVESAVEKAVEKTVKKAI 54
                  5688888888888877765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (132 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1788  (0.0997267); expected 358.6 (0.02)
Passed bias filter:                      746  (0.0416086); expected 358.6 (0.02)
Passed Vit filter:                        88  (0.00490825); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              19  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.43
# Mc/sec: 913.34
//
Query:       EEA21040.1  [L=904]
Description: PHD finger and SET domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-06   28.8   1.4    7.8e-06   26.4   0.3    2.6  2  SET       SET domain
      1e-05   25.3  11.8      2e-05   24.4  11.8    1.5  1  PHD       PHD-finger
  ------ inclusion threshold ------
        2.8    7.6   5.8          5    6.8   5.8    1.4  1  PHD_2     PHD-finger


Domain annotation for each model (and alignments):
>> SET  SET domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.4   0.3   1.3e-09   7.8e-06     110     165 ..     348     398 ..      47     402 .. 0.78
   2 ?   -3.0   0.0       1.4   8.2e+03      64      78 ..     541     555 ..     484     625 .. 0.60

  Alignments for each domain:
  == domain 1  score: 26.4 bits;  conditional E-value: 1.3e-09
                 EEETEEEEEECCCGTTGGGCEEXSSSSEEEEEEEE.TTSSEEEEEESSXBXTTEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxx RF
         SET 110 sidaralksgngagplarflNHsCdpNcnltvqnv.lrgprvavfAtrdIkkGeElt 165
                 +id  ++++g+      r++  sC+pN+++ ++   + +++++++A +dI+++ E+t
  EEA21040.1 348 YID--SREEGSIL----RYVRRSCRPNVTMKTYITnEVEYHFCFVANQDIPADSEIT 398
                 244..33555555....***********7777766999******************9 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.4
                 HHHHHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxx RF
         SET  64 lqklakdqkqaeked 78 
                  ++l+ dq+ + k++
  EEA21040.1 541 FEQLEHDQHGQRKKK 555
                 222222222222222 PP

>> PHD  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4  11.8   3.3e-09     2e-05       2      51 ..      48      91 ..      47      92 .. 0.90

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 3.3e-09
                BTTTTSTTSTTSCEEEETTTSCEEETTTSSSTHSHHSHHSSTBSSTTTHT CS
         PHD  2 CavCkkksdeeeelvqCdgCkrwfHqkClkppleseekpegewlCekCke 51
                C +C   +d+++++v+C++C++w+H +C+   +e   +p+ e +C+ C++
  EEA21040.1 48 C-ICAF-EDDDGNTVFCEKCETWQHIECYYHGQE---VPD-EHFCTDCSP 91
                8.****.9*********************99977...554.79*****86 PP

>> PHD_2  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   5.8   0.00084         5       5      35 ..      60      89 ..      57      90 .. 0.83

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.00084
       PHD_2  5 lsCdkCsvaVHasCYGvskesdgeeWlCrrC 35
                ++C kC++  H +CY   +e   +e  C  C
  EEA21040.1 60 VFCEKCETWQHIECYYHGQEVP-DEHFCTDC 89
                89*************8777665.47889888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (904 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       988  (0.0551063); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.70u 0.28s 00:00:00.98 Elapsed: 00:00:00.44
# Mc/sec: 6151.85
//
Query:       EEA21041.1  [L=381]
Description: nuclear pore protein (SEH1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    5.9e-14   52.2  16.7     0.0003   21.5   1.9    4.7  4  WD40         WD domain, G-beta repeat
      2e-06   28.0   0.2      0.091   13.1   0.0    3.3  3  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
  ------ inclusion threshold ------
      0.033   13.1   0.2        2.5    7.0   0.0    2.6  3  Ge1_WD40     WD40 region of Ge1, enhancer of mRNA-decapping p
      0.046   12.1   0.0      0.067   11.6   0.0    1.2  1  Rav1p_C      RAVE protein 1 C terminal


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.2   4.4e-07     0.002       8      38 .]      10      41 ..       2      41 .. 0.81
   2 !    5.6   0.3    0.0071        32       1      37 [.      47      86 ..      47      87 .. 0.71
   3 !   14.5   0.1   1.1e-05     0.049       6      37 ..     221     257 ..     217     258 .. 0.79
   4 !   21.5   1.9   6.6e-08    0.0003       9      38 .]     329     359 ..     319     359 .. 0.85

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 4.4e-07
                ESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  8 tGHss.vtslafspdgawlasGsdDgtvriWd 38
                +GH + vt  +f+ +g+ +++Gs D+ +++Wd
  EEA21041.1 10 SGHRDlVTVTKFNFYGNRIVTGSSDHRLKVWD 41
                599445766679**********99*******9 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0071
                TEEEEEEESS.SSEEEEEEETTSSE.......EEEE..ETTSEEEEE CS
        WD40  1 gqclrtltGH.ssvtslafspdgaw.......lasG..sdDgtvriW 37
                +q++ t+++H   +++       +w       ++ G  ++D  ++iW
  EEA21041.1 47 WQLTDTWRAHdAEIRDA------TWngpftgqHI-GsvGEDMRLKIW 86
                57788999996669999......55555566655.52357******* PP

  == domain 3  score: 14.5 bits;  conditional E-value: 1.1e-05
                 EEESSSS.EEEEEEETTSSE..........EEEEETTSEEEEE CS
        WD40   6 tltGHss.vtslafspdgaw..........lasGsdDgtvriW 37 
                 +ltGH++ v+++      +w          +asG++Dg vri+
  EEA21041.1 221 ELTGHGGlVRDI------SWangsvrgydlIASGCKDGFVRIF 257
                 589**6679*99......55555555777699*********97 PP

  == domain 4  score: 21.5 bits;  conditional E-value: 6.6e-08
                 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 
                  H  +v+ +++s  g+ l+s++dDg+vr+W+
  EEA21041.1 329 SHhLDVWQVQWSFAGDCLISSGDDGSVRFWK 359
                 56466**************9999*******6 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.0     0.029   1.3e+02      37      72 ..      12      47 ..       5      68 .. 0.74
   2 !   13.1   0.0     2e-05     0.091      13      69 ..     199     261 ..     190     278 .. 0.79
   3 !    7.9   0.0   0.00081       3.6      23      66 ..     318     359 ..     315     375 .. 0.83

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.029
  ANAPC4_WD40 37 edsevrsLaWkpdgklLavaysdgevrlldaesgkv 72
                 +   v+  +++  g+ ++ + sd ++++ d ++g+ 
   EEA21041.1 12 HRDLVTVTKFNFYGNRIVTGSSDHRLKVWDQKDGQW 47
                 5667888899999*****************999975 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 2e-05
  ANAPC4_WD40  13 atedgellvfRlngqr.vwtl.eedkedsevrsLaWkpdg....klLavaysdgevrlldaes 69 
                  + + + + ++R++  r  +++ e +++++ vr+++W +       l+a +++dg vr++++++
   EEA21041.1 199 VAAMDTVKIYRTDSSRrFYHAvELTGHGGLVRDISWANGSvrgyDLIASGCKDGFVRIFEVYT 261
                  55667899999977550555578899**********8743222469**************996 PP

  == domain 3  score: 7.9 bits;  conditional E-value: 0.00081
  ANAPC4_WD40  23 RlngqrvwtleedkedsevrsLaWkpdgklLavaysdgevrlld 66 
                  R + ++v  +  d++   v +++W+  g  L  + +dg+vr+ +
   EEA21041.1 318 RHEYREVACI--DSHHLDVWQVQWSFAGDCLISSGDDGSVRFWK 359
                  6666777777..789999**********************9864 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.1      0.78   3.5e+03     260     280 ..      28      50 ..      14      58 .. 0.56
   2 ?    7.0   0.0   0.00056       2.5     190     219 ..     232     262 ..     180     276 .. 0.62
   3 ?    3.1   0.0    0.0082        37     184     216 ..     327     360 ..     312     368 .. 0.81

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 0.78
    Ge1_WD40 260 itgadnnselklWsce..lWtCl 280
                 i + + ++ lk+W  +   W+ +
  EEA21041.1  28 IVTGSSDHRLKVWDQKdgQWQLT 50 
                 33344456677776542245544 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.00056
    Ge1_WD40 190 iveaafspdGt.alatasedGevkffqvyle 219
                 i+ a  s  G   +a  ++dG+v+ f vy +
  EEA21041.1 232 ISWANGSVRGYdLIASGCKDGFVRIFEVYTF 262
                 44444455554157999************76 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.0082
    Ge1_WD40 184 ieehs.liveaafspdGtalatasedGevkffqv 216
                 i++h   + +  +s  G  l  +  dG v+f++ 
  EEA21041.1 327 IDSHHlDVWQVQWSFAGDCLISSGDDGSVRFWKK 360
                 555554789999999*****************85 PP

>> Rav1p_C  RAVE protein 1 C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   1.5e-05     0.067      45     118 ..      29     103 ..       6     110 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 1.5e-05
     Rav1p_C  45 vvdesrseLsiwdlksgvleyeeef.eeedsikdldwtstpdsqsilavgFekkvllltqlRydylnkgpswaai 118
                 v  +s ++L +wd k+g++  + ++  ++ +i+d  w+   ++q i +vg + +  ++ +   +  n+g+ + +i
  EEA21041.1  29 VTGSSDHRLKVWDQKDGQWQLTDTWrAHDAEIRDATWNGPFTGQHIGSVGEDMRLKIWQEDVTQPPNSGRRFKSI 103
                 5578999******************666779*******************9888888877777777777766666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (381 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       351  (0.0195772); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.47u 0.24s 00:00:00.71 Elapsed: 00:00:00.40
# Mc/sec: 2836.43
//
Query:       EEA21042.1  [L=469]
Description: UDP-N-acetyl-glucosamine-1-P transferase Alg7, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.5e-32  112.8  11.8    1.5e-32  112.8  11.8    2.5  3  Glycos_transf_4  Glycosyl transferase family 4


Domain annotation for each model (and alignments):
>> Glycos_transf_4  Glycosyl transferase family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   1.2       0.1   1.9e+03     116     131 ..      87     102 ..      12     110 .. 0.52
   2 !  112.8  11.8   8.4e-37   1.5e-32       3     159 ..     146     321 ..     144     322 .. 0.88
   3 ?   -2.7   0.1      0.29   5.2e+03     113     128 ..     426     441 ..     404     456 .. 0.51

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.1
  Glycos_transf_4 116 llalallgallGfllf 131
                      ++a+++l  +++f++f
       EEA21042.1  87 VCAVVYLLLMIAFIPF 102
                      2222333334444444 PP

  == domain 2  score: 112.8 bits;  conditional E-value: 8.4e-37
  Glycos_transf_4   3 lllltillilllGflDDvlglkarlKlilqilaalililtld..lslttlglllt.....qvlielglilavlltllvivgvtNavNliDGldG 89 
                      + ll++ +i+llG+ DD+l++++r+K+++ +l a+++++++   +++t++ +++       ++++lg +++v+++ ++i++  N++N+++G++G
       EEA21042.1 146 SGLLSLQAITLLGIGDDLLDIRWRHKVLIPALGAFPMLVVYFvdFGVTHVVVPMPlqryfGQIFDLGFLYYVYMAAVAIFCP-NSINMLAGVNG 238
                      56788889*****************************9999866666666555557676669********************.*********** PP

  Glycos_transf_4  90 laagvsiiialalvvla.............avdgrsellllalallgallGfllfNrypAkvFmGDsgslflGlvlavlailg 159
                      +++++s++ia++l++               a+d++  +++++l ++g+ l++l++N+yp+kvF+GD++ +f+G+v+av+ ilg
       EEA21042.1 239 VEVAQSLVIAVLLLLNDllylgpftpfphpAMDSHLFSIYFLLPFIGVSLALLCHNWYPSKVFVGDTYCYFAGMVFAVVGILG 321
                      **********999888799999*9998877777777777777777778899****************************9987 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 0.29
  Glycos_transf_4 113 ellllalallgallGf 128
                      + l+l+++ll  ++G+
       EEA21042.1 426 DRLALSIVLLQTVCGL 441
                      3334444444444442 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (469 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       491  (0.0273858); expected 358.6 (0.02)
Passed bias filter:                      239  (0.0133304); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.49
# Mc/sec: 2907.33
//
Query:       EEA21043.1  [L=325]
Description: pyrroline-5-carboxylate reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.7e-19   68.1   4.2    9.4e-19   67.6   2.8    1.9  2  P5CR_dimer     Pyrroline-5-carboxylate reductase dimerisation
    4.8e-08   33.5   0.2    0.00014   22.3   0.0    2.9  3  F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
  ------ inclusion threshold ------
       0.04   13.3   0.7        1.3    8.4   0.3    2.3  2  2-Hacid_dh_C   D-isomer specific 2-hydroxyacid dehydrogenase,


Domain annotation for each model (and alignments):
>> P5CR_dimer  Pyrroline-5-carboxylate reductase dimerisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0       0.5     3e+03      37      54 ..     167     184 ..     154     201 .. 0.69
   2 !   67.6   2.8   1.6e-22   9.4e-19       1      99 [.     207     314 ..     207     318 .. 0.91

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.5
                 HHHHHHHHHHHHHHHHHH CS
  P5CR_dimer  37 eeArelaaqtvaGaakll 54 
                  ++  l+ +tvaGa + l
  EEA21043.1 167 RQSATLISETVAGADTTL 184
                 567778888888887655 PP

  == domain 2  score: 67.6 bits;  conditional E-value: 1.6e-22
                 CCHHHHHHHHTTTHHHHHHHHHHHHHHHHHHTT--HHHHHHHHHHHHHHHHHHHH...CHS......HHHHHHH.H--TTSHHHHHHHHHHHTTHHHHH CS
  P5CR_dimer   1 EkqldavtalsGsgpAyvflliealadagvklGlsreeArelaaqtvaGaaklll...ese......paelrdk.vtspgGtTiaglkeleegglraav 89 
                 E++++ ++++sG +pA++++++e +a+ ++++Gls+ +A+ laaq+++G+a+++l   e e      ++e+rd+ ++s +G+ ++g+ +l+e+++++++
  EEA21043.1 207 ESLMNSASMISGLAPAFYTVALEGIAKEAITKGLSEPDAMFLAAQALKGTAEMILsrrE-EnkglfvVDEVRDQaISSSAGSGARGVVVLREAAVKDSF 304
                 899**************************************************976531.2568999999999857889******************** PP

                 HHHHHHHHHH CS
  P5CR_dimer  90 ieaveaaakr 99 
                 +ea+ + +++
  EEA21043.1 305 AEAMGQGMEK 314
                 ****999886 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.1   0.1   0.00068       4.1       2      19 ..       7      24 ..       6      30 .. 0.87
   2 !   22.3   0.0   2.4e-08   0.00014      25      96 ..      48     128 ..      41     129 .. 0.92
   3 ?   -2.6   0.0       1.4   8.4e+03      67      68 ..     248     249 ..     228     276 .. 0.50

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00068
                   EEEETTSHHHHHHHHHHH CS
  F420_oxidored  2 igiiGaGnmgealasgll 19
                   ++iiG+G++g ++++ ll
     EEA21043.1  7 LAIIGCGQIGTSILEVLL 24
                   89***********99776 PP

  == domain 2  score: 22.3 bits;  conditional E-value: 2.4e-08
                    GGCEEEEEESSCCCHHHHHHHHC.........-EEECECHHHHHHH-SEEEE-S-HHHHHHHHHHC.GHHHHTTSEEEEESS CS
  F420_oxidored  25 pheivvansrnpekaeelaeelg.........vkvtavdneeaaeeadvvvlavkpedveevlsel.akdalkgklvisvla 96 
                    p+ ++ a+ ++++++  l+ ++g         v+++++   e++++ad+++l +++++++++ls+   ++ l+gkl++s++a
     EEA21043.1  48 PSRFI-ACVNTQDSVSRLRTKFGhlacnsypnVQISQGRVIEVVAQADIILLGCRTSQATDILSDPsLREHLAGKLLLSTCA 128
                    55666.99*******************************************************98767999********997 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 1.4
                    E- CS
  F420_oxidored  67 la 68 
                    la
     EEA21043.1 248 LA 249
                    22 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   0.3   0.00021       1.3      36      55 ..       4      23 ..       2      29 .. 0.89
   2 ?    2.8   0.0     0.011        68      84     108 ..      85     109 ..      70     141 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00021
                  TSEEEEES-SHHHHHHHHHH CS
  2-Hacid_dh_C 36 gktvGiiGlGrIGqavakrl 55
                  g t++iiG+G+IG+++ ++l
    EEA21043.1  4 GTTLAIIGCGQIGTSILEVL 23
                  78************998876 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.011
                   SHHHHHHH-SEEEE-S--STTTTTS CS
  2-Hacid_dh_C  84 sleellaesDivslhlpltpetrhl 108
                    + e++a++Di+ l +  +++t  l
    EEA21043.1  85 RVIEVVAQADIILLGCRTSQATDIL 109
                   56799***********988777544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (325 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       526  (0.0293379); expected 358.6 (0.02)
Passed bias filter:                      456  (0.0254337); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2272.23
//
Query:       EEA21044.1  [L=304]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (304 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       466  (0.0259914); expected 358.6 (0.02)
Passed bias filter:                      383  (0.021362); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.47u 0.24s 00:00:00.71 Elapsed: 00:00:00.40
# Mc/sec: 2265.54
//
Query:       EEA21045.1  [L=391]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    0.00057   19.2   0.0    0.00083   18.7   0.0    1.3  1  Dynamin_M  Dynamin central region


Domain annotation for each model (and alignments):
>> Dynamin_M  Dynamin central region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   4.6e-08   0.00083     148     227 ..      47     130 ..      18     185 .. 0.78

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 4.6e-08
   Dynamin_M 148 iFnetle.kslek..idpleelsdeeirtairnsrGrelplfvpekaFealvkkqikkleepalkcvelVyeelekivek.lek 227
                 i+++ ++ +++ +  i +++e  +e ir+++ ++rG+el+  ++ ++   l+++  + + + a++++  +++++e +v++ +++
  EEA21045.1  47 IYQQGFNrAAVPQgiIPFTKEDMTEHIRHLMLQTRGKELSSSTNSMVVADLFRENSAPWGDLAHDYIASIWKAVEGFVHQaITQ 130
                 5555555322222445667777789******************************************************95554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (391 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       561  (0.0312901); expected 358.6 (0.02)
Passed bias filter:                      493  (0.0274974); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2726.12
//
Query:       EEA21046.1  [L=255]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.8e-32  112.1   0.0    3.5e-32  111.8   0.0    1.1  1  Dynamin_N     Dynamin family
     0.0001   22.4   0.1     0.0004   20.5   0.1    1.9  1  MMR_HSR1      50S ribosome-binding GTPase
  ------ inclusion threshold ------
      0.017   14.9   0.0      0.031   14.0   0.0    1.4  1  AAA_15        AAA ATPase domain
      0.056   13.2   0.0        0.1   12.4   0.0    1.4  1  AAA_29        P-loop containing region of AAA domain
      0.077   12.5   0.1        5.7    6.5   0.1    2.3  2  FeoB_N        Ferrous iron transport protein B
       0.13   11.6   0.1       0.46    9.8   0.0    1.9  2  FtsK_SpoIIIE  FtsK/SpoIIIE family
       0.18   12.1   0.6       0.38   11.0   0.2    1.7  2  AAA_28        AAA domain


Domain annotation for each model (and alignments):
>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.8   0.0   1.4e-35   3.5e-32       1     167 [.      43     235 ..      43     236 .. 0.83

  Alignments for each domain:
  == domain 1  score: 111.8 bits;  conditional E-value: 1.4e-35
                 EEEEEBTTTTHHHHHHHHHTS--S---SSS---S-EEEEE............CCT---C....CS...SSEEEET-EB--CHHHHHH.....HHHHHHH CS
   Dynamin_N   1 iavvGsqSsGKSSvlnaLlgedilprgpnptTrrplelql............geeeeas....eravkeelkekekkledfsevree.....ieketek 78 
                 i+v+G qSsGKSS+l+a+ g ++  +g +p+Tr p+e+ l                       ++a++ +l+++++ le f+e+        i +++++
  EEA21046.1  43 IIVCGGQSSGKSSILEAISGIPFPIKGGGPCTRFPIEVVLcntsqtgvhvsiV-----PdesrSKAEILSLRDFSETLEGFDEIPAVvkeagIVMQKST 136
                 89**************************************7766666666662.....03333467888888887777777777655000223445555 PP

                 HHTSSSS--SS-EEEEEEETTS-SEEEEE---B-SSSGTTS.........HHHHHHH.STTEEEEEEEETTS-CCC-CHHHHHHHHSTTBTTEEEEEE- CS
   Dynamin_N  79 iagankgiskkvillkilsllvkgltlvDlPGldsvnkrdq.........elvkeyi.kkadiilavtsanhdlsnsealflarevdpkgkrtivvltk 167
                 + ++ ++  k+v+ ++i ++++++l ++DlPGl ++   +q         ++vk+yi k+++iilav sa+ + +n+  l++ r vd++++rt++++tk
  EEA21046.1 137 SRRQENAYFKDVLRIQIAGPDQPHLIIIDLPGLPRSFSDQQvtkdaqlvhDIVKSYIaKPETIILAVISAEDSYTNQPILNMVRGVDQNDSRTLGIITK 235
                 55556666666************************99999899*******************************************************9 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5   0.1   1.5e-07    0.0004       1      93 [.      42     213 ..      42     238 .. 0.79

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 1.5e-07
                 EEEEEESTTSSHHHHHHHHHTSTEEESSSTTSSSSEEEEEEEETTEE.................................................... CS
    MMR_HSR1   1 evaivGrpNvGKStLinaltgekaivsdkpgtTrdinegrvklkgke.................................................... 47 
                 ++++ G   +GKS+++ a++g    ++    +Tr ++e  +  + ++                                                    
  EEA21046.1  42 RIIVCGGQSSGKSSILEAISGIPFPIKGGGPCTRFPIEVVLC-NTSQtgvhvsivpdesrskaeilslrdfsetlegfdeipavvkeagivmqkstsrr 139
                 68999****************99999999999****999887.223357788888888899999999999999************************** PP

                 .....................EEEEECGGCS.........SHHHHHHHHHHHHHHHHCTSEEEEEEETTTTCSHHH CS
    MMR_HSR1  48 .....................ielvDtpGli.........egaseekglgkaflaleeadlillvvdaseeklkpl 93 
                                      ++++D+pGl          ++a+  +++ k++ a+ e  +il v++a+ ++++++
  EEA21046.1 140 qenayfkdvlriqiagpdqphLIIIDLPGLPrsfsdqqvtKDAQLVHDIVKSYIAKPE-TIILAVISAE-DSYTNQ 213
                 *****************************85433332222245555578888887666.8999999866.445332 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   1.2e-05     0.031      26      43 ..      43      60 ..      25      64 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1.2e-05
      AAA_15 26 tvliGkNnsGKSsileal 43
                 +++G ++sGKSsilea+
  EEA21046.1 43 IIVCGGQSSGKSSILEAI 60
                689**************9 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   3.9e-05       0.1      16      44 ..      35      62 ..      20      68 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 3.9e-05
      AAA_29 16 tieidlkgatlltGpsGsGKSTllDAiqa 44
                ++ i++   +++ G + sGKS++l Ai+ 
  EEA21046.1 35 QHLISMPR-IIVCGGQSSGKSSILEAISG 62
                44455445.8999*************975 PP

>> FeoB_N  Ferrous iron transport protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.0     0.016        40       3      23 ..      43      63 ..      41      67 .. 0.89
   2 ?    6.5   0.1    0.0022       5.7      47      89 ..     159     207 ..     148     220 .. 0.77

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.016
                EEEEESTTSSHHHHHHHHHTT CS
      FeoB_N  3 valvGnpnvGkttlfnaltga 23
                ++++G + +Gk+++++a++g 
  EEA21046.1 43 IIVCGGQSSGKSSILEAISGI 63
                7899**************985 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0022
                 EEEEEEE----...SSSSSSSHHHHHHHHHHH...CTSSSEEEEEEEGG CS
      FeoB_N  47 keveivDlPGi...Yslsayseeekvardfll...eeepdvvvnvvdat 89 
                  ++ i+DlPG    +s ++++++ ++++d++     +   +++ v+ a+
  EEA21046.1 159 PHLIIIDLPGLprsFSDQQVTKDAQLVHDIVKsyiAKPETIILAVISAE 207
                 56889*****877788899****99999988633234455666777665 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0      0.97   2.5e+03     216     231 ..       7      30 ..       4      39 .. 0.67
   2 ?    9.8   0.0   0.00018      0.46      35      58 ..      37      59 ..      24      60 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.97
                   HHHHHHHHHHHCG........GGT CS
  FtsK_SpoIIIE 216 vedaivRlarkgr........aag 231
                   + da++Rl++k+r        + +
    EEA21046.1   7 QTDALTRLCDKNRlellntidNLR 30 
                   678899999998865555555444 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00018
                  GGGS-.SEEEE--TTSSHHHHHHH CS
  FtsK_SpoIIIE 35 lkkmashllvaGatgsGKStalnt 58
                  l++m+  ++v+G++ sGKS  l +
    EEA21046.1 37 LISMP-RIIVCGGQSSGKSSILEA 59
                  67889.9*************9987 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.2   0.00015      0.38       1      20 [.      42      61 ..      42      74 .. 0.91
   2 ?   -2.3   0.0       1.9   4.8e+03      26      56 ..     124     152 ..     108     154 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00015
      AAA_28  1 kivitGgestGKTtlleaLa 20
                +i++ Gg+s+GK+++lea++
  EEA21046.1 42 RIIVCGGQSSGKSSILEAIS 61
                799**************986 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1.9
      AAA_28  26 vvpEaareileeklakgedalpwvedllafa 56 
                 vv+Ea+  + ++ ++++e+a    +d+l+++
  EEA21046.1 124 VVKEAGIVMQKSTSRRQENAYF--KDVLRIQ 152
                 5688887777777776666333..4666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (255 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       465  (0.0259356); expected 358.6 (0.02)
Passed bias filter:                      437  (0.0243739); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.48u 0.30s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 1695.47
//
Query:       EEA21047.1  [L=369]
Description: dihydroorotase, homodimeric type [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.8e-07   31.3   0.0    2.8e-07   30.6   0.0    1.3  1  Amidohydro_2  Amidohydrolase
      3e-05   23.5   0.3    0.00043   19.7   0.3    2.5  1  Amidohydro_1  Amidohydrolase family


Domain annotation for each model (and alignments):
>> Amidohydro_2  Amidohydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.6   0.0   3.1e-11   2.8e-07      93     215 ..      80     210 ..      56     279 .. 0.71

  Alignments for each domain:
  == domain 1  score: 30.6 bits;  conditional E-value: 3.1e-11
                   SSHCHHHHHHHHHHHHTTECEEEEESSTTTCCTTTCGGH....HHHHHHHHHHT-EEEEE.............CHHHCHHHHHHHHHHHHHHHCCHH CS
  Amidohydro_2  93 ldpedaaaeleraveelgfkGvrlnphvggddllgdrld....rpifealeelglpvdihtGps.........pewlfggpqettraiqplllsgva 176
                   l+   + +e+e+a+++  + Gv+++p+    +  +  ld    +p+f+a+e+++l++ +h G            ++ ++     +++  +++l+ + 
    EEA21047.1  80 LHNGLTEEEIEKAAKSGVVYGVKFYPAGVTTNSQEGVLDieqlYPVFAAMEKHDLVLNLH-GEMistpasavgKQTEPVVTVLNAEPLFIPQLAKLH 175
                   555678899*****999999******997666666666677779****************.655888455555555555555588889999****** PP

                   HHCTTSEEEESGGGTTTTCHHHHHHHHHHHHHCCEEECC CS
  Amidohydro_2 177 rkfPnlkivlaHgGgpserlraalellarrpnvyvklsg 215
                   + fP+l+ivl H +   ++l a+++    +pnv   + +
    EEA21047.1 176 AAFPKLRIVLEHVSTK-QGLDAVRAC---GPNVAGTITA 210
                   ************9987.555555555...5666655544 PP

>> Amidohydro_1  Amidohydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.3   4.9e-08   0.00043       8     252 ..      16     270 ..      11     298 .. 0.67

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 4.9e-08
                   EEEEECETTECSSSGHHHHHSTTHHHHHHHHHHHHHHHHTTEEEEEEEEHSSTH..HHHHHHHHHHT...SSSEEEEEEESSEGGSGCCCSHHHHHH CS
  Amidohydro_1   8 DaHvHleqsllrgatledwlvppetaaealesgiktalksGtttvadmgattst..giealleaaee...lplglrilggkvsldrgsaetskasre 99 
                   D+HvHl+q+                  +++e ++    k+G+ tv  m++ t++  +++  +e  e+   l++++ +l +         +    + e
    EEA21047.1  16 DMHVHLRQD------------------AMMELCTPLVEKGGCDTVFIMPNLTPKigSVSQAIEYHEKlqrLAPNVKFLMS------LYLH-NGLTEE 87 
                   899999866..................45778888888999999999999888787555555544444446666666666......3323.233444 PP

                   HHHHHHHHHHHHCTTTCEE.EEEEECGTCCSHHH......HHHHHHHHHHHHTTEEEEEE..TSSCHHHHHHHHHHTTTEEEETTTTSTCC...... CS
  Amidohydro_1 100 klkagaaetikgkadgvvk.valapheapafsde......elkealkeakkrdlpvaiHa..letkgevedaeaafgetiehgthlevaes...... 181
                   ++++ a       ++gvv+ v+++p++ +++s+e      +l+ ++ + +k+dl +  H    +t++     + + + t+  +              
    EEA21047.1  88 EIEKAA-------KSGVVYgVKFYPAGVTTNSQEgvldieQLYPVFAAMEKHDLVLNLHGemISTPASAVGKQTEPVVTVLNAE------Plfipql 171
                   554444.......7889999**************888888888888899999********774444443222222222333333......2344444 PP

                   ...........................HHTTTHCCEEEHCTCEEEHHHHHHHHHHHHHHCEE.......HHHHHHHHSEHHHHHHHHHHHH.TSCEE CS
  Amidohydro_1 182 ...........................lglldeiklilahgvhltpteaellkerlkeagva.......hcpfsnsilrsgrealrkalde.Gvkvg 243
                                              ++ ++++ +i ah  h+t                        + +++  +  ++r al ka+ + + k++
    EEA21047.1 172 aklhaafpklrivlehvstkqgldavrACGPNVAGTITAHHLHITI---------------DdavsdvfNFCKPVAKTPEDRLALVKAVVDgSGKFF 253
                   7776555566666666555555555555555555555555555553...............1444444589999999**************7778** PP

                   EEEECT........TSS CS
  Amidohydro_1 244 lgtDga........asg 252
                   +g+D+a        ++g
    EEA21047.1 254 FGSDSAphpiqskkGAG 270
                   ****9988887666333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (369 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       348  (0.0194099); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 2559.28
//
Query:       EEA21048.1  [L=772]
Description: 3-isopropylmalate dehydratase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
   4.2e-163  543.6   0.0   5.1e-163  543.4   0.0    1.1  1  Aconitase    Aconitase family (aconitate hydratase)
    1.8e-41  141.5   0.0    4.8e-41  140.2   0.0    1.8  1  Aconitase_C  Aconitase C-terminal domain


Domain annotation for each model (and alignments):
>> Aconitase  Aconitase family (aconitate hydratase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  543.4   0.0  5.7e-167  5.1e-163       1     461 []      13     472 ..      13     472 .. 0.96

  Alignments for each domain:
  == domain 1  score: 543.4 bits;  conditional E-value: 5.7e-167
   Aconitase   1 ekiwdahlvee..eg..iayvpdrvllqdvtgvqalvdlaaareavrrlggtlatidhlvpvdlvidhsvgaeealeknledefernkeryefLksaak 95 
                 +k++++h+v+e  +g  + y+ dr+l+++vt++qa+++l +a+++vrr+++tl+t+dh++p++     s ++ +++e+ ++++ +r   ++ +L+++ k
  EEA21048.1  13 DKVFEDHIVNEqdDGtiLIYI-DRHLVHEVTSPQAFEGLTNAGRKVRRPDCTLSTVDHNIPTT-----SRKTFKNAETFVKETDSR--LQVMTLEENVK 103
                 699999*99554455745555.*****************************************.....666667788999988888..9********** PP

   Aconitase  96 afgirvvppg...qGIvHqvnlEyglalpgktvvgtDSHTtmigglGvlaiGvGgieaeavllgqplelkipkvvgvkltGklkegvtakDlvlavigk 191
                 +fg++++ ++   qGIvH +++E+g++lpg+tvv++DSHT+++g++G+la+G+G++e+e+vl++q+l +k+ k+++++++G+l +gv++kD+vl++ig 
  EEA21048.1 104 KFGLTYFGMDddrQGIVHIIGPEQGFTLPGTTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLLTKRSKNMRIQVDGELYPGVSSKDVVLHIIGV 202
                 *********9999************************************************************************************** PP

   Aconitase 192 lrkkgvvgkvvEffGegvesLsledraTiaNMaaEvGAttglfpvdektleYLkatgreeaav.lveaydkaqalf.elaadedaeydkvleldlstle 288
                 ++++g++g+v+Ef+G+ +++Ls+e+r++i+NM++E+GA++g++++de t+eYLk  gr+ a++   ++++ka++++ +l++de+a+yd+++ +d++++ 
  EEA21048.1 203 IGTAGGTGCVIEFCGSVIRALSMEARMSICNMSIEAGARAGMVAPDEITFEYLK--GRPLAPKyGSAEWKKAVNYWsSLQSDEGAKYDSEVFIDAKDII 299
                 ******************************************************..******988899********88********************* PP

   Aconitase 289 psvagpkrPqdavplselvk.k.efkeelekeaaekaley.klkegtklkdgkvdiaaigSCTNssnedvraaagllakavekglkvkpgv.ktsvaPG 383
                 p+v+++++Pqd++p+++ v+ + +f++e++k + ++aley +l++gt+lk+++vd+++igSCTN+++ed+r aa++++     g+k+++++  ++++PG
  EEA21048.1 300 PTVSWGTSPQDVLPITGVVPsPdDFEDEVRKLSCKRALEYmGLTSGTPLKEIPVDKVFIGSCTNARIEDLRSAAKVVE-----GRKIASNIkAAMIVPG 393
                 *******************97669******************************************************.....********7789**** PP

   Aconitase 384 SevvkayleaeGlleiLekaGfevvgagCstCig.nsdrleegeaivsssNRNFegRqgpntrayLaSPelvvaaAlaG 461
                 S+ vk+++eaeGl++i+ +aGfe+++agCs+C+g n+d l+++e+++s+sNRNFegRqg+++r++L+SP +++aaA+aG
  EEA21048.1 394 SGLVKKQAEAEGLDKIFIDAGFEWREAGCSMCLGmNPDILSPRERCASTSNRNFEGRQGAHGRTHLMSPTMAAAAAIAG 472
                 ******************************************************************************9 PP

>> Aconitase_C  Aconitase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.2   0.0   5.3e-45   4.8e-41       2     129 ..     535     657 ..     534     659 .. 0.97

  Alignments for each domain:
  == domain 1  score: 140.2 bits;  conditional E-value: 5.3e-45
                  CCCCCCTT--CHHHHSTGGGCCGHCCHHHCCCGGTTTCCCCTTTSBBSEEEETTTTEEEEHHHHHHHHHHTT--EEEE--SSBTBS---THHHHHHHH CS
  Aconitase_C   2 ekllklkGlttedeksnvdtdlkipkqfegtianiglgnelveekrankttdlddgekedvvdaaerykkegaklvviagknfGeGSSRehAAkalrl 99 
                  +k++ lkG++++ +++n+dtd++ipkqf++ti+++glg++l++e+r+n +t++   e +++v++ e+y+  ++k++v++g nfG+GSSRehA++al++
   EEA21048.1 535 PKFTVLKGIAAPMDRANIDTDAIIPKQFLKTIKRTGLGSALFYEWRFNTETGA---ELPEFVLNNEPYR--NSKILVVTGPNFGCGSSREHAPWALLD 627
                  68999*********************************************997...8899*********..9************************** PP

                  TTEEEEEES-B-HHHHHHHHHTT-EEEEES CS
  Aconitase_C 100 lGikaviaeSFerIfennliknglLplefk 129
                  +Gik++ia+SF++If nn +kng+Lp+ + 
   EEA21048.1 628 FGIKVIIAPSFADIFFNNTFKNGMLPIPIT 657
                  **************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (772 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       374  (0.0208601); expected 358.6 (0.02)
Passed bias filter:                      349  (0.0194657); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 5125.94
//
Query:       EEA21049.1  [L=2412]
Description: alpha-1,3-glucan synthase Ags2 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.4e-17   63.0   1.8    2.1e-16   60.4   1.1    2.5  2  Alpha-amylase    Alpha amylase, catalytic domain
    2.1e-15   57.1   0.1    4.3e-15   56.1   0.1    1.5  1  Glyco_transf_5   Starch synthase catalytic domain
    3.7e-05   23.3   0.0      8e-05   22.2   0.0    1.5  1  Glycos_transf_1  Glycosyl transferases group 1
  ------ inclusion threshold ------
      0.016   15.2   0.0      0.046   13.7   0.0    1.7  1  Glyco_transf_4   Glycosyltransferase Family 4
       0.23   10.9   5.8       0.53    9.7   5.8    1.5  1  DUF373           Domain of unknown function (DUF373)


Domain annotation for each model (and alignments):
>> Alpha-amylase  Alpha amylase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.4   1.1     6e-20   2.1e-16       1     218 [.      98     347 ..      98     354 .. 0.74
   2 ?   -1.0   0.0      0.29     1e+03     309     331 ..     474     496 ..     453     498 .. 0.80

  Alignments for each domain:
  == domain 1  score: 60.4 bits;  conditional E-value: 6e-20
                    --CHHHHCTCCCCCCCT-SCEEE-..B-CE-S-TTTTSS-SCECCE-CCC--CCCCCCHHHHHHCTT-EEEEEE--SC--TTSCC........... CS
  Alpha-amylase   1 GDLkGiiekLdYlkeLGvtaiwls..PifkspqadhgYdiadytkidpefGtnedlkeLiskahekgikvilDlVvNHtsdehew........... 83 
                    GD  G+i+ LdYl+++G++ai+l+    +++p    gY + d t +d+++G+ + +   i+++h++g++vi+D     ++d               
     EEA21049.1  98 GDVVGLIDTLDYLQGMGIKAIYLAgtALMNQPWGFDGYSALDTTLLDQHYGDIATWRSAITEIHNRGMYVIFDNTLATMGDLLGFegylnttapfi 193
                    9**********************7225667999*******************************************99999988888999999986 PP

                    .CHCCHHST.TSGGGCCC-E.............................ESS-STTC-TTTTCSCEE..CTTTTCEEESSS-TTS-BB-TTTCCCC CS
  Alpha-amylase  84 .fkeslkkk.gepkrdyyiwkegk.......................eekeppnnwkslfdgsawey..dekaqeyylhlflkklpdLnteneevr 152
                      ++++++k  +++ d++++++ +                        +   +++  ++ d +a+    d ++    l +f++ ++ L   n++vr
     EEA21049.1 194 hQEHKVQYKsSRQYVDFHFGNDYNttceyprfynetgypvdsyvyddLKGCYNSDFDQYGDIEAFGVfpDYER---ELAKFASVQDRLREWNPSVR 286
                    6222233220233555555555559998888887766666555443311222222222333333333333333...4999**************** PP

                    CCCCC.CCCCCCTTT-SEEEETTCCCTTTCCCCHCCHCCHHHHHHHHHHHTCCGTT-EEEEE-TT-S CS
  Alpha-amylase 153 kelkd.vvkfwlekgidGfRlDvvkhvskvealesngeflheftqalnetvasrkevmtvgEvssda 218
                    ++l + ++ +    ++dGfR D + +       +  g++ + ++q + +   +++++++ gE+ +++
     EEA21049.1 287 EKLIRhACIIIASLDVDGFRYDKATQATV----DALGDMSEGWRQCARAH--GKENFFLSGEITGGN 347
                    ***997888888888*******9888777....55667777777766644..467788888887765 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.29
                    HHHHCCCTSSSEEEEETTCCCT- CS
  Alpha-amylase 309 laaillltlrGvpviYyGeEigm 331
                     + i +l ++G p +  GeE+g+
     EEA21049.1 474 GMFITTLHMPGAPLVLWGEEQGF 496
                    45677899*************97 PP

>> Glyco_transf_5  Starch synthase catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.1   0.1   1.2e-18   4.3e-15       3     213 ..    1163    1366 ..    1161    1370 .. 0.77

  Alignments for each domain:
  == domain 1  score: 56.1 bits;  conditional E-value: 1.2e-18
  Glyco_transf_5    3 lfvasEv..apl...aktGGLadvvgaLpkaLaklghdvrvilPrygaikeek.keleevaelskaaedevevev..ekvkvaklkkdgvdvy 87  
                      +++++E+    +   +k GGL+ +++ + k L+++  d   ++P  g+++  + + +e ++          +v    ++vkv  +  ++++++
      EEA21049.1 1163 MIATMEYdiEDWaikIKIGGLGVMAQLMGKNLSHQ--DLIWVVPCVGDVEYPEdQPAEPMFV---------TVLGnsYEVKVQYHVLRNITYV 1244
                      6667776552334459****************996..899******8888866222222222.........22213477888888889***** PP

  Glyco_transf_5   88 fldnpeffdreg..lYgdkgedyednaerfalfsraalelleklgwkpdvihahDWhtalvpallkelykerglfkkiktvftiHNlayqgrf 178 
                      +ld+p f ++++  +Y ++  d  d a  ++++++ ++e++++  +  d+ h++D+h +l+p++l  +         i+ ++++HN ++qg +
      EEA21049.1 1245 LLDAPVFRQQTKtePY-PARMDDLDSAIYYSAWNQCIAEAMKR--FPIDLYHINDYHGSLAPLYLLPQT--------IPACLSLHNAEFQGLW 1326
                      ******99755568**.4588889*******************..579*****************9977........**************** PP

  Glyco_transf_5  179 p......kdel.aalglp.aedfekldglefygkvnflkagiv 213 
                      p      kde+ + ++l+ +      + ++f + +n+l+ag  
      EEA21049.1 1327 PmrtqneKDEVcSVFNLDvNV---ATRYVQFGEVFNLLHAGAS 1366
                      *87776655555667777222...3456677777888887765 PP

>> Glycos_transf_1  Glycosyl transferases group 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.2   0.0   2.2e-08     8e-05      12     112 ..    1451    1553 ..    1443    1571 .. 0.76

  Alignments for each domain:
  == domain 1  score: 22.2 bits;  conditional E-value: 2.2e-08
                       TTT-EEEEEESS-TTTTTHHHHHHHHHCCCCCHCSCEEEEEES......STTHHHHHHHHHHHCTTCGGGEEECCHSSSHHHHHHC.ESEEE CS
  Glycos_transf_1   12 nekkkiilsvgrlekeKgvdllikafallkkqlnpnvklviaG.....ngeeekelkklaeelelsdnviflgevsredleellkn.adifv 97  
                       n +  ++++vgr + +Kg+dl+ ++++++ ++ +pnv+l+ +G      g+  +   +++ +l  +      ++    +l++++ + a  ++
       EEA21049.1 1451 NPDADLLVFVGRWSMQKGIDLIADVMPSVLEA-RPNVQLICIGpvidlYGKFAALKLDRMMKLYPGRVFSRPQFT---ALPSYIFSgAEFAL 1538
                       6778899************************9.**********99986444433333333333333444444444...566666556***** PP

                       EEESSBSS-HHHHHH CS
  Glycos_transf_1   98 lpsisEgfGivllEA 112 
                       +ps+ E+fG+v++E 
       EEA21049.1 1539 IPSRDEPFGLVAVEF 1553
                       *************95 PP

>> Glyco_transf_4  Glycosyltransferase Family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   1.3e-05     0.046      59     117 ..    1275    1331 ..    1220    1337 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.3e-05
  Glyco_transf_4   59 aflrrlrrllkrekpDvvHahspaalgaallalrrrlgiplVltvHglyekrllkarlk 117 
                      a  + +++++kr+ +D+ H+++++  +a l  l     ip  l++H+ + ++l++ r +
      EEA21049.1 1275 AWNQCIAEAMKRFPIDLYHINDYHGSLAPLYLLP--QTIPACLSLHNAEFQGLWPMRTQ 1331
                      333468999****************999988777..7***********98777776655 PP

>> DUF373  Domain of unknown function (DUF373)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   5.8   0.00015      0.53     190     315 ..    2128    2255 ..    2115    2278 .. 0.67

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00015
      DUF373  190 lylllrGfgldelleelleklkesleegritfvtyvvallllligiisgyislesvssasvssglltlilafiygavewlalailtaslgkiideyl 286 
                  ++l ++G +l ++ +  l+ ++ ++++ +it +t+ +a++l +igi+ ++    +++ ++  +    +  +f  +++ w+ + +l+  +        
  EEA21049.1 2128 VALWYWGSSLSKQTQAGLTAVQPIVNSWKITAITVPIAVMLWAIGILLAFGL-PDYYRQTPGKVASFYKSIFRRKIIMWFFVTVLIQNFFLSAPYG- 2222
                  67889*****************************************999766.6666644444444444557778888887777776654333322. PP

      DUF373  287 kre.....ekdiarllllpflvlaiglvlygasa 315 
                   r+     +++ a+++ +++lv+ + ++++g++ 
  EEA21049.1 2223 -RNwsflwSSKHASTWQIVLLVVLFFVLVWGIML 2255
                  .232344434444455555555555555555432 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2412 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       615  (0.034302); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 1.14u 0.32s 00:00:01.46 Elapsed: 00:00:00.50
# Mc/sec: 14409.15
//
Query:       EEA21050.1  [L=244]
Description: orotate phosphoribosyltransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.6e-12   46.6   0.3    4.4e-12   45.8   0.3    1.3  1  Pribosyltran  Phosphoribosyl transferase domain


Domain annotation for each model (and alignments):
>> Pribosyltran  Phosphoribosyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.8   0.3   2.4e-16   4.4e-12      29     133 ..      82     190 ..      72     198 .. 0.93

  Alignments for each domain:
  == domain 1  score: 45.8 bits;  conditional E-value: 2.4e-16
                   GGEEEEEEETTTHHHHHHHHHHS.............TT-EE-EEEEEE-TTT--EE........EE----TTSEEEEE-SEESSSHHHHHHHHHHHC CS
  Pribosyltran  29 kpdvvvgiargGvpfakiladeL.............evplayvrkvkyrpdgseeaargssdesrlledpagkkVliVDDildtGgTllaalelLke 112
                   + d+v+g+a++G+p    + +eL             ++ + + rk+ ++++ +++++          + ++gk+VliVDD+++ G++l++a+ ++ +
    EEA21050.1  82 NFDIVFGPAYKGIPECVGVVNELatrdalagtktwdNISYSFNRKEAKDHGEGGNIV---------GAPLKGKRVLIVDDVITAGTALREAVGIIQK 169
                   789*****************************************************5.........6789*************************** PP

                   C-BSEEEEEEEEE-HHHHHHH CS
  Pribosyltran 113 kgpeevriavlvdkpateeev 133
                   +g  + +++ l+d+ +++ + 
    EEA21050.1 170 EGGVVAGVVLLFDRQERVSDT 190
                   ***999999999999998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (244 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       310  (0.0172904); expected 358.6 (0.02)
Passed bias filter:                      281  (0.0156729); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.48
# Mc/sec: 1536.75
//
Query:       EEA21051.1  [L=607]
Description: methylenetetrahydrofolate reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.6e-115  385.3   0.0   2.2e-115  384.9   0.0    1.1  1  MTHFR     Methylenetetrahydrofolate reductase


Domain annotation for each model (and alignments):
>> MTHFR  Methylenetetrahydrofolate reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  384.9   0.0  1.2e-119  2.2e-115       1     286 [.       6     292 ..       6     293 .. 0.99

  Alignments for each domain:
  == domain 1  score: 384.9 bits;  conditional E-value: 1.2e-119
                 HHHHHHT.SS-EEEEEE---SSHHHHHHHHHHHHHHGGGG-SEEEE---CCCTTHHHHHHHHHHHHHHH-S-EEEEEESTTS-HHHHHHHHHHHHHCT- CS
       MTHFR   1 kleqaleegkalisfEffpPkteegernLleridrleevkplfvdvTwgaggstaeltssiakviqqelgleailhlTctdaskeeldkalekakelGi 99 
                 kl++++++g++ isfE+fpPkt++g++nL++r+dr++ ++p f+dvTwgaggs++elt +++  +q+ +gle+++hlTctd+++e +d+ale a+++G+
  EEA21051.1   6 KLQEQAATGRPGISFEYFPPKTAQGVQNLYDRMDRMHDLGPAFIDVTWGAGGSRSELTCEMVRIAQTVFGLETCMHLTCTDMPRERVDAALEAAYNAGC 104
                 57788899******************************************************************************************* PP

                 -EEEEE--S--TT-GGC---S----SHHHHHHHHHHHHCGGSEEEEEE-TT--TT-S-HHHHHHHHHHHHHCT--EEEEEE-S-HHHHHHHHHHHHHCT CS
       MTHFR 100 rnilALrGDppkdedkweekeeefkyaldLvrlireeygdlfdigvaaYPevhpeaksleadlkylkeKvdaGAdfiitQlffdvdkflkfveqvreag 198
                  nilALrGDpp++++kwe+ e++f+ya+dLv++ire+yg++fdigv +YPe+   ++++++ + +lkeKvdaG+ fi+tQ+f+dvd+fl++ve++r++g
  EEA21051.1 105 TNILALRGDPPREQEKWEAAEGGFRYAKDLVKYIREKYGNHFDIGVGGYPEGADDNPDVDQLIDHLKEKVDAGSTFIVTQMFYDVDNFLNWVEKCRAKG 203
                 *************************************************************************************************** PP

                 -SS-EEEEE---SSHHHHHHHHHHHT----HHHHCCCTCHCT-HHHHHHHHHHHHHHHHHHHHHCT.--EEEEE-TT--HHHHHHHHHC CS
       MTHFR 199 idipiipgimpiksykslkrlaklskvkiPqelldrleeikdddeavkkigielavemvkkllaeg.vkglHlytlnkekaileileql 286
                 i+  i+pgimpi++y+++ r+ +++k++iP   l++le++k+dd++v+++g++l+ em++klla+g +++lH+yt+n+++a++ ile+l
  EEA21051.1 204 INAAIVPGIMPISTYDAFMRRSNWTKIRIPPDWLEKLEPVKADDAKVREVGTKLVAEMCRKLLASGhIHHLHFYTMNLAQATRLILEEL 292
                 **************************************************************************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (607 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       430  (0.0239835); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.47
# Mc/sec: 3903.51
//
Query:       EEA21052.1  [L=1046]
Description: NTP binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1046 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2299  (0.128228); expected 358.6 (0.02)
Passed bias filter:                      652  (0.0363657); expected 358.6 (0.02)
Passed Vit filter:                       103  (0.00574488); expected 17.9 (0.001)
Passed Fwd filter:                        18  (0.00100396); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 1.22u 0.34s 00:00:01.56 Elapsed: 00:00:00.52
# Mc/sec: 6067.09
//
Query:       EEA21053.1  [L=460]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-37  127.2   4.3    5.5e-37  126.2   0.6    2.8  4  DUF2418   Protein of unknown function (DUF2418)
  ------ inclusion threshold ------
      0.013   15.0   0.9      0.025   14.1   0.9    1.5  1  FIN1      Filaments in between nuclei protein-1


Domain annotation for each model (and alignments):
>> DUF2418  Protein of unknown function (DUF2418)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0     0.072   6.5e+02      13      33 ..       9      29 ..       6      65 .. 0.84
   2 ?   -3.7   0.1         2   1.8e+04      15      24 ..      91     100 ..      79     110 .. 0.49
   3 !  126.2   0.6   6.1e-41   5.5e-37       1      96 []     166     270 ..     166     270 .. 0.99
   4 ?   -1.6   0.0      0.44     4e+03       3      19 ..     285     301 ..     283     308 .. 0.79

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.072
     DUF2418 13 kfslrlftlFsPlhvlllvll 33
                ++s rl  +F+P  +ll+++ 
  EEA21053.1  9 PLSERLANFFNPWDFLLWISE 29
                78899***********99984 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 2
     DUF2418  15 slrlftlFsP 24 
                 +++ +tlFs 
  EEA21053.1  91 IVHTLTLFSS 100
                 2233333333 PP

  == domain 3  score: 126.2 bits;  conditional E-value: 6.1e-41
     DUF2418   1 devweLsvWdpskfslrlftlFsPlhvlllvlll.........sesvlktlllvvllslqlylliskfeqqikDkkiiqkevleEYnekfVkPrlnvlv 90 
                 ++vwe++vWdp ++slrlf++FsP+hvl+++l+l         s+++++t++l++ll++q+++l s+f+qq+kD ++++kev++EY++kfV+Pr+++l+
  EEA21053.1 166 RDVWEIAVWDPFPLSLRLFCSFSPGHVLVYWLFLptlptdprpSVTIFTTIVLAILLTVQMSFLSSSFSQQSKDLAVVHKEVMHEYDTKFVHPRTQPLM 264
                 68************************************************************************************************* PP

     DUF2418  91 rdvavq 96 
                 rdv+vq
  EEA21053.1 265 RDVGVQ 270
                 ****97 PP

  == domain 4  score: -1.6 bits;  conditional E-value: 0.44
     DUF2418   3 vweLsvWdpskfslrlf 19 
                 + +++ W+p++++ r f
  EEA21053.1 285 YNQVELWTPTHIINRGF 301
                 678999***99877665 PP

>> FIN1  Filaments in between nuclei protein-1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.9   2.8e-06     0.025      15     110 ..     295     395 ..     280     406 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 2.8e-06
        FIN1  15 nvFkr.LstsPskrklnk.elskpparlspkksskskssiqvtpkrlasPecLkdykp...kvtqsldrpqfkkeskatkiesndsvtnivfptSPtki 108
                 ++ +r ++tsP+ ++l++   ++   ++sp+++++   ++ ++  +l+ P++L+d  p   +   ++ +pqf++ +++t   + +s       +SP + 
  EEA21053.1 295 HIINRgFKTSPNPNYLAHvDPESTGRQVSPSRRQSFMPTNSQAGVQLQTPSHLRDSSPvvqNQLSNIRQPQFRPPTTSTGTGDGGSLGVYSHANSPFRK 393
                 66777799*********9666777889*****9999999****************99833333446699***999998877777777777777888776 PP

        FIN1 109 tF 110
                 ++
  EEA21053.1 394 SM 395
                 64 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (460 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       493  (0.0274974); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.24s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 3067.62
//
Query:       EEA21054.1  [L=123]
Description: V-type ATPase F subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.7e-32  111.0   0.0    3.1e-32  110.8   0.0    1.0  1  ATP-synt_F  ATP synthase (F/14-kDa) subunit


Domain annotation for each model (and alignments):
>> ATP-synt_F  ATP synthase (F/14-kDa) subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.8   0.0   1.7e-36   3.1e-32       2      91 .]      14     117 ..      13     117 .. 0.98

  Alignments for each domain:
  == domain 1  score: 110.8 bits;  conditional E-value: 1.7e-36
                 EEEESHHHHHHHHHTTCEEEE..............CSSHHHHHHHHHHHHH.HTTEEEEEEEHHHHCCCHHHHHHCTCSSSSEEEEESCSCCGGSHHCH CS
  ATP-synt_F   2 avIGdedtvtgfrlaGvgeve..............vtdeeeieealkelle.redigiilitekiaeeirelideykeealPaileIPskegpydeekd 85 
                 avIGded+vtg++laG+g+v+              +t++++ie+a++++++ r+dig++li+++iae+ir  +d++++ a+Pa+leIPsk++pyd+ekd
  EEA21054.1  14 AVIGDEDSVTGLLLAGIGHVTeppdsqrnflvvdsKTETSAIEKAFHNFTQeRKDIGVLLINQHIAERIRLSVDSFTD-AFPAVLEIPSKDHPYDPEKD 111
                 9*************************************************99**************************.******************** PP

                 HHHHHH CS
  ATP-synt_F  86 svrkkv 91 
                 sv+++v
  EEA21054.1 112 SVLRRV 117
                 ***997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (123 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       433  (0.0241508); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.24s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 925.08
//
Query:       EEA21055.1  [L=169]
Description: ML domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.1e-25   87.8   0.1      1e-24   87.5   0.1    1.1  1  E1_DerP2_DerF2  ML domain
  ------ inclusion threshold ------
       0.19   11.5   0.0       0.19   11.5   0.0    1.2  1  Alph_Pro_TM     Putative transmembrane protein (Alph_Pro_TM)


Domain annotation for each model (and alignments):
>> E1_DerP2_DerF2  ML domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.5   0.1   1.1e-28     1e-24       2     130 ..      42     163 ..      41     166 .. 0.95

  Alignments for each domain:
  == domain 1  score: 87.5 bits;  conditional E-value: 1.1e-28
                     -EEEESSTTTSSEEEEEEEEEESSECEECTSEEEEEEEEEECSSBBSSEEEEEEEEETTEEEEE-BSSEETCHHHHHHTTTT-SSSB-TCEEEEE CS
  E1_DerP2_DerF2   2 vsfedCgankddavtvksveisppcplkrgqnltisadgstsdeissglkaevevkvggwikvpfelpetddaCkvlelgegleCPikageyvty 96 
                     +++e+C+++k+d++++ sv+++p+ p+ +g+ lti+a+g   + +++g k++++vk+g +i++  +   + d+C+++e +  l+CP++  ++  +
      EEA21055.1  42 NPLEYCANPKNDILEIISVNLTPN-PPIPGEILTIEAEGIFHEAVEQGSKIHLQVKYG-LIRLVNV---EADLCDEIEGNTDLTCPLEGHKK--F 129
                     6899**99**************99.********************************9.7******...88****************98888..5 PP

                     EEEEES-CCCHSCEEEEEEEEEECTTEEEEEEEE CS
  E1_DerP2_DerF2  97 tlslplpselpngkyrvelelldedgkeltCvki 130
                      +++++p+e+p+gky+v +++++ed+ ++tC+++
      EEA21055.1 130 AKEVEIPKEVPPGKYTVLADVYTEDKVRITCLQA 163
                     7******************************986 PP

>> Alph_Pro_TM  Putative transmembrane protein (Alph_Pro_TM)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   2.1e-05      0.19     145     174 ..     125     154 ..      32     160 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 2.1e-05
  Alph_Pro_TM 145 dgtlfraevalPanvpeGkytvevyllrdg 174
                  +++ f +ev++P +vp+Gkytv + +  ++
   EEA21055.1 125 GHKKFAKEVEIPKEVPPGKYTVLADVYTED 154
                  56779****************977665555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (169 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       235  (0.0131073); expected 358.6 (0.02)
Passed bias filter:                      226  (0.0126053); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.36u 0.22s 00:00:00.57 Elapsed: 00:00:00.37
# Mc/sec: 1386.23
//
Query:       EEA21056.1  [L=531]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.1e-13   49.5   0.0      7e-13   48.7   0.0    1.4  1  Methyltransf_23  Methyltransferase domain
    5.4e-11   43.1   0.0    2.2e-10   41.1   0.0    2.1  1  Methyltransf_25  Methyltransferase domain
      5e-10   39.9   0.0    1.2e-09   38.7   0.0    1.7  1  Methyltransf_11  Methyltransferase domain
    7.6e-06   25.8   0.0    0.00013   21.7   0.0    2.8  2  Methyltransf_31  Methyltransferase domain
    9.2e-06   26.3   0.0    2.2e-05   25.1   0.0    1.7  1  Methyltransf_12  Methyltransferase domain
     0.0026   17.9   0.0      0.006   16.7   0.0    1.5  1  FtsJ             FtsJ-like methyltransferase
     0.0028   17.1   0.0     0.0055   16.2   0.0    1.4  1  Methyltransf_4   Putative methyltransferase
  ------ inclusion threshold ------
       0.03   13.6   0.0      0.055   12.7   0.0    1.4  1  Methyltransf_2   O-methyltransferase domain
       0.16   11.5   0.0       0.33   10.5   0.0    1.4  1  MTS              Methyltransferase small domain


Domain annotation for each model (and alignments):
>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.7   0.0   3.5e-16     7e-13       3     163 ..     285     457 ..     283     459 .. 0.81

  Alignments for each domain:
  == domain 1  score: 48.7 bits;  conditional E-value: 3.5e-16
  Methyltransf_23   3 aqreeelsdklerllpklraggrvLdiGcGtGillevlren..gfsvtgvDlspeaveiae.......kakkaqkdqfdeqeaaepqgkfdlIv 87 
                       q+++ + d+++ ++p    + rvLd G+G G+++ + +e+   ++v+gvD+sp+++++          +  +++  f       p+++fdl++
       EEA21056.1 285 QQVFNLVFDNRL-IFPPIHNPRRVLDCGYGAGNWALEVAERypHCQVIGVDISPHMQPLDIpdnlwlqVDNLNRPFTF-------PSRHFDLVH 370
                      678888889998.7777999*************999996653345**********99986577777766666666666.......********* PP

  Methyltransf_23  88 lrevlehvp..dppellrqiatllkpgGylllse..plasl.....kedrllldw..lylvpagrhisffsarslkelleeaGlevv 163
                      +r v   ++   + +++r + + +k gG++   e  +++ +       +++l++w  +y++  +++  +  a  l+ l+ +aGle+v
       EEA21056.1 371 SRLVASGLDrsRWSSYVRDLVRVTKRGGWVQMAEiyFNVQSdngsiTDRHALREWsrRYMRALEDLKDLRAAPRLASLMTAAGLEDV 457
                      *********644*****************988886534433667665777777775446655559999*****************98 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.1   0.0   1.1e-13   2.2e-10       1      97 []     307     398 ..     307     398 .. 0.86

  Alignments for each domain:
  == domain 1  score: 41.1 bits;  conditional E-value: 1.1e-13
                      EEEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHHTTT.TEEEEESBCCG.BSSSTTTEEEEEEESTGGGSSHHHHHHHHHHHHHH CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlgkakvtgvDiseemleaareraeeegl.nvefvqgdaed.lpfedgsfDlvvssgalhhlsdedlekalkeiarv 92 
                      vLd+G G G+++l++a+r+++++v+gvDis+ m       +    + n+ +++ ++++ + f++++fDlv+s+ + + l+++++  +++ + rv
       EEA21056.1 307 VLDCGYGAGNWALEVAERYPHCQVIGVDISPHMQPLD---I----PdNLWLQVDNLNRpFTFPSRHFDLVHSRLVASGLDRSRWSSYVRDLVRV 393
                      9******************99************5542...2....22456677777445889**********877777**************** PP

                      EEEEE CS
  Methyltransf_25  93 LkpgG 97 
                      +k gG
       EEA21056.1 394 TKRGG 398
                      ****9 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.7   0.0     6e-13   1.2e-09       1      94 [.     308     400 ..     308     402 .. 0.87

  Alignments for each domain:
  == domain 1  score: 38.7 bits;  conditional E-value: 6e-13
                      EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-EEEETTEECCC.TSS-TT-EEEEEEES-CCC-..CCHHHHHHHHHHHEE CS
  Methyltransf_11   1 LdvGcGtGrlaealakrg..arvvgvDlskemlklakekaseeglkvefvvadaek.lpfednsfDlvvssevlhhv..edpekalkeiaRvLk 89 
                      Ld+G G+G  a ++a+r+  ++v+gvD+s+ m       ++++     ++v ++ + + f++  fDlv s+ v   +   +++++++ ++Rv k
       EEA21056.1 308 LDCGYGAGNWALEVAERYphCQVIGVDISPHMQ---PLDIPDNL---WLQVDNLNRpFTFPSRHFDLVHSRLVASGLdrSRWSSYVRDLVRVTK 395
                      8**************9999*************9...44555553...356666666458******************888************** PP

                      EEEEE CS
  Methyltransf_11  90 pgGll 94 
                       gG++
       EEA21056.1 396 RGGWV 400
                      ***86 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0      0.43   8.6e+02      63      84 ..     278     297 ..     260     304 .. 0.77
   2 !   21.7   0.0   6.7e-08   0.00013       5      40 ..     305     339 ..     301     437 .. 0.84

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.43
  Methyltransf_31  63 ieeleklledekfDlilsnevl 84 
                      i  le  l+++ f+l+++n ++
       EEA21056.1 278 IDRLE--LQQQVFNLVFDNRLI 297
                      34455..899********9876 PP

  == domain 2  score: 21.7 bits;  conditional E-value: 6.7e-08
  Methyltransf_31   5 lrvlDlGCGtGeltfelaeelgpkaevvGiDiseea 40 
                       rvlD+G G+G+ ++e a e +p+++v+G+Dis+++
       EEA21056.1 305 RRVLDCGYGAGNWALEVA-ERYPHCQVIGVDISPHM 339
                      68****************.889***********986 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1   0.0   1.1e-08   2.2e-05       1      98 [.     308     399 ..     308     400 .. 0.88

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 1.1e-08
  Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvelealdlldldggssfDlvvasnvlhhl..kdirevldnirkl 92 
                      L+ G G G+ + +++e+ p+++++gvDisp++           +  +n ++++++l+   ++++ +fDlv++  v + l    + ++++ + ++
       EEA21056.1 308 LDCGYGAGNWALEVAERYPHCQVIGVDISPHMQ--------PLDIPDNLWLQVDNLNRPFTFPSRHFDLVHSRLVASGLdrSRWSSYVRDLVRV 393
                      79999***************************9........344445677888888888889999**************988888********* PP

  Methyltransf_12  93 LkpgGr 98 
                       k gG+
       EEA21056.1 394 TKRGGW 399
                      *****8 PP

>> FtsJ  FtsJ-like methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0     3e-06     0.006      19      61 ..     301     345 ..     276     379 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 3e-06
                 S-TT-EEEECT-TTSHHHHHHCCT.T.-SEEEEEES.SSSHHH..T CS
        FtsJ  19 fkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDl.qpmapl..p 61 
                 +++ ++v+D+g++ G+w+  +++r  + ++v++vD+  +m+pl  p
  EEA21056.1 301 IHNPRRVLDCGYGAGNWALEVAERYPH-CQVIGVDIsPHMQPLdiP 345
                 345578******************765.********5555777444 PP

>> Methyltransf_4  Putative methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   2.8e-06    0.0055       5      35 ..     307     337 ..     303     344 .. 0.92

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 2.8e-06
                     EEEET-TTSHHHHHHHHHSTTSEEEEEES-H CS
  Methyltransf_4   5 vleiGcGkGeflvalAkknPdknflGiEirv 35 
                     vl+ G G G++ ++ A++ P+++++G++i+ 
      EEA21056.1 307 VLDCGYGAGNWALEVAERYPHCQVIGVDISP 337
                     799*************************976 PP

>> Methyltransf_2  O-methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   2.8e-05     0.055      47      95 ..     288     336 ..     253     341 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.8e-05
                     HHHHHHHHHHSS-GGG-SEEEEET-TTSHHHHHHHHH-TT-EEEEEE-H CS
  Methyltransf_2  47 sslvakkvleafdleglkslvDvGGGtGalakaivsayPtikvivfDlp 95 
                      +lv ++ l    +++ ++++D G G+G  a ++++ yP+++vi  D++
      EEA21056.1 288 FNLVFDNRLIFPPIHNPRRVLDCGYGAGNWALEVAERYPHCQVIGVDIS 336
                     55555555555556777899************************99985 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00017      0.33      32      64 ..     304     336 ..     292     339 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00017
                 CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESB CS
         MTS  32 sgkvlDlGcGaGvlgaalakespeaevtlvdvd 64 
                  ++vlD G GaG  ++++a+++p+ +v  vd++
  EEA21056.1 304 PRRVLDCGYGAGNWALEVAERYPHCQVIGVDIS 336
                 467*************************99997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (531 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       508  (0.028334); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.56u 0.24s 00:00:00.80 Elapsed: 00:00:00.40
# Mc/sec: 4014.71
//
Query:       EEA21057.1  [L=349]
Description: rRNA assembly protein Mis3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.5e-31  106.8   0.0    9.5e-31  105.7   0.0    1.6  1  KH_8      Krr1 KH1 domain
  ------ inclusion threshold ------
      0.031   14.1   0.0       0.09   12.6   0.0    1.9  1  KH_1      KH domain


Domain annotation for each model (and alignments):
>> KH_8  Krr1 KH1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  105.7   0.0   1.1e-34   9.5e-31       1      81 []      38     118 ..      38     118 .. 0.99

  Alignments for each domain:
  == domain 1  score: 105.7 bits;  conditional E-value: 1.1e-34
        KH_8   1 SsfevlfpkyrekylkeveekikklleekklklevdlkerslkvsTtekTrDPyiilkardlikLisrgvpleeakkvleD 81 
                 Ssf +lfpkyre ylke ++ i+++le++ + +++dl e+s++v+Tt+kT+DP  il+ardlikL++r+vp+++a k+leD
  EEA21057.1  38 SSFMTLFPKYREVYLKEAWPLITRTLEKQGIACTLDLVEGSMTVKTTRKTFDPAAILNARDLIKLLARSVPVQQALKILED 118
                 89******************************************************************************9 PP

>> KH_1  KH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0     1e-05      0.09      11      61 ..     141     183 ..     133     194 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1e-05
                 HHHHHTGGGHHHHHHHHHHT-EEEEESSTT...T.-EEEEEESHHHHHHHH CS
        KH_1  11 vgriIGkgGsnIkeIreetgakIkvpksedegsderevtisGspeavekAk 61 
                   ri+G++Gs++k ++  t ++I v  +       ++v   G+ ++ ++ +
  EEA21057.1 141 RQRILGPNGSTLKALELLTSTYILVQ-G-------NTVSAMGPFKGLKEVR 183
                 579*************999***9976.3.......2455555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (349 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2093  (0.116738); expected 358.6 (0.02)
Passed bias filter:                      578  (0.0322383); expected 358.6 (0.02)
Passed Vit filter:                       121  (0.00674884); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.69u 0.31s 00:00:01.00 Elapsed: 00:00:00.49
# Mc/sec: 2154.52
//
Query:       EEA21058.1  [L=309]
Description: rRNA assembly protein Mis3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-29  101.3   0.0    5.2e-29  100.2   0.0    1.6  1  KH_8      Krr1 KH1 domain
  ------ inclusion threshold ------
      0.024   14.4   0.0      0.074   12.9   0.0    1.9  1  KH_1      KH domain
          7    6.9  22.2         11    6.3  22.2    1.3  1  Vfa1      AAA-ATPase Vps4-associated protein 1


Domain annotation for each model (and alignments):
>> KH_8  Krr1 KH1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.2   0.0   8.8e-33   5.2e-29       5      81 .]       2      78 ..       1      78 [. 0.99

  Alignments for each domain:
  == domain 1  score: 100.2 bits;  conditional E-value: 8.8e-33
        KH_8  5 vlfpkyrekylkeveekikklleekklklevdlkerslkvsTtekTrDPyiilkardlikLisrgvpleeakkvleD 81
                +lfpkyre ylke ++ i+++le++ + +++dl e+s++v+Tt+kT+DP  il+ardlikL++r+vp+++a k+leD
  EEA21058.1  2 TLFPKYREVYLKEAWPLITRTLEKQGIACTLDLVEGSMTVKTTRKTFDPAAILNARDLIKLLARSVPVQQALKILED 78
                69**************************************************************************9 PP

>> KH_1  KH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   1.2e-05     0.074      11      61 ..     101     143 ..      92     155 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.2e-05
                 HHHHHTGGGHHHHHHHHHHT-EEEEESSTT...T.-EEEEEESHHHHHHHH CS
        KH_1  11 vgriIGkgGsnIkeIreetgakIkvpksedegsderevtisGspeavekAk 61 
                   ri+G++Gs++k ++  t ++I v  +       ++v   G+ ++ ++ +
  EEA21058.1 101 RQRILGPNGSTLKALELLTSTYILVQ-G-------NTVSAMGPFKGLKEVR 143
                 579*************999***9976.3.......2555555555555555 PP

>> Vfa1  AAA-ATPase Vps4-associated protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3  22.2    0.0019        11      67     131 ..     225     300 ..     195     308 .. 0.54

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0019
        Vfa1  67 e......leeeiekv.kkeyeekqkkkkekekkkkekd....kkdkdkkkekekdkkkekekeeekkkelkkaeee 131
                 e      +++  e+v k+e++ekq++k+e++ k+++kd    ++d dkk++k+k k++++  e+++kk++kk++++
  EEA21058.1 225 EsgeyflSKQAKERVrKEEIQEKQREKREEKMKERQKDfvppTEDADKKEKKKKRKHADDGGESTEKKKKKKSKSK 300
                 2445675444444542678999999999988888888899763333333333333333333222222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2387  (0.133136); expected 358.6 (0.02)
Passed bias filter:                      679  (0.0378716); expected 358.6 (0.02)
Passed Vit filter:                       145  (0.00808746); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.32s 00:00:00.97 Elapsed: 00:00:00.47
# Mc/sec: 1975.87
//
Query:       EEA21059.1  [L=282]
Description: stress protein DDR48, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-07   31.0   0.0        1.8    8.3   0.0    3.9  4  DUF4573   Domain of unknown function (DUF4573)


Domain annotation for each model (and alignments):
>> DUF4573  Domain of unknown function (DUF4573)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.0   0.0    0.0011        20      23      75 ..      68     120 ..      50     123 .. 0.82
   2 !    7.3   0.0    0.0002       3.6      23      65 ..     123     164 ..     117     179 .. 0.80
   3 !    8.3   0.0    0.0001       1.8      27      82 ..     171     217 ..     158     221 .. 0.51
   4 !    6.7   0.0   0.00031       5.5      25      70 ..     222     257 ..     218     280 .. 0.45

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0011
     DUF4573  23 pqpggkddplgaeekkkdlravteveplkgvaeieplkavseiqPlravserd 75 
                 +++ ++ d  g ++kk d+++ ++ + ++g+++ ++    s ++ ++++s++ 
  EEA21059.1  68 SYGSSNNDSYGSSNKKSDSYGSSNNNDSYGSSNKKSDSYGSSNNDSYGSSNKK 120
                 7899999*************************999876666666677777665 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0002
     DUF4573  23 pqpggkddplgaeekkkdlravteveplkgvaeieplkavsei 65 
                 +++ ++ d  g +++ +d+++ ++ ++++g+++++ +++ s++
  EEA21059.1 123 SYGSSNNDSYGSNNNNNDSYGSSNKNSSYGSSNTD-SYGSSNN 164
                 67888899999999999999999999999999999.5555555 PP

  == domain 3  score: 8.3 bits;  conditional E-value: 0.0001
     DUF4573  27 gkddplgaeekkkdlravteveplkgvaeieplkavseiqPlravserdplgavee 82 
                 +k d  g ++         + + ++g+ + +++++ s+++ ++++s+++++++ ++
  EEA21059.1 171 KKSDSYGSSN---------NNDDSYGSNNKNSSYGSSNNNDSYGSSNKNSSYGASN 217
                 2333333333.........4455666666666666666666666666666665554 PP

  == domain 4  score: 6.7 bits;  conditional E-value: 0.00031
     DUF4573  25 pggkddplgaeekkkdlravteveplkgvaeieplkavseiqPlra 70 
                 + ++ +  +++++ +d+++ ++ ++++g ++ +          +++
  EEA21059.1 222 GSSNKNSSYGSSNNNDSYGSSNKNSSYGASNND----------SYG 257
                 333333334444444444444444444444444..........222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (282 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       827  (0.0461264); expected 358.6 (0.02)
Passed bias filter:                      121  (0.00674884); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                        23  (0.00128284); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.86u 0.33s 00:00:01.19 Elapsed: 00:00:00.51
# Mc/sec: 1664.01
//
Query:       EEA21060.1  [L=346]
Description: alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-20   74.0   0.0    1.9e-20   73.2   0.0    1.4  1  ADH_zinc_N    Zinc-binding dehydrogenase
    1.6e-15   56.9   0.1    2.7e-15   56.2   0.1    1.4  1  ADH_N         Alcohol dehydrogenase GroES-like domain
    8.3e-10   39.8   0.0    1.4e-09   39.1   0.0    1.4  1  ADH_zinc_N_2  Zinc-binding dehydrogenase
    0.00031   20.2   0.1    0.00061   19.2   0.1    1.4  1  2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, 
    0.00052   19.4   0.7     0.0013   18.1   0.0    1.8  2  AlaDh_PNT_C   Alanine dehydrogenase/PNT, C-terminal domain
  ------ inclusion threshold ------
       0.13   12.3   0.0       0.29   11.2   0.0    1.5  1  Shikimate_DH  Shikimate / quinate 5-dehydrogenase


Domain annotation for each model (and alignments):
>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.2   0.0   6.3e-24   1.9e-20       1     129 [.     174     301 ..     174     302 .. 0.91

  Alignments for each domain:
  == domain 1  score: 73.2 bits;  conditional E-value: 6.3e-24
                 HHHHHHHHHHHHTT-.EEEEEESSHHHHHHHHH.TTESEEEETTTCHHHHHHHHHTTTSSEEEEEESSCSHHH.HHHHHHCEEEEEEEEECSCTSSEEE CS
  ADH_zinc_N   1 gvGlaavqlAkalGa.eviavdsseeklelakk.lGadevinykeadlverikeltggegvdvvfecvGsgat.leaalkllkpgGrlvvvGggkgeee 96 
                 g+G++++ +AkalG+ +v+a++++++k++ a + lGad +i ++e   ++  ++ t  + +d+++ +v s++  l+++l+ll+ gG++v vG+++g+ +
  EEA21060.1 174 GLGHLGILFAKALGCeRVVAISRTSSKRKDAVEgLGADLFIATEE---DK-KWARTYSRSLDLIICTVDSPKLpLSQYLRLLRVGGTFVQVGAPEGPLP 268
                 89**************************999888*********65...44.44455579*********98875599*********************** PP

                 .EEHHHHHHTT-EEEEE-SSCHHHHHHHHHHHHH CS
  ADH_zinc_N  97 .fdlrnlllkeksilGsllgslreefkealdlla 129
                  +++  l+ ke++i+Gs+ gs +++++e+l+l+a
  EEA21060.1 269 gLPAWSLIQKEVQITGSNIGS-PDDIREMLQLAA 301
                 *********************.*********976 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.2   0.1     9e-19   2.7e-15       2      75 ..      31     112 ..      30     127 .. 0.92

  Alignments for each domain:
  == domain 1  score: 56.2 bits;  conditional E-value: 9e-19
                 TEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS.........--TT-EEEE-SEEE-SSSHHHHT CS
       ADH_N   2 gevlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkk.........lkvGdrVvvepliscgeCaaCke 75 
                 +++ + ++ +giCg+Dlh+l+   ++++ +p+++GHEi+G+v+ +g++v +         ++vGdrV + +++   ++++  +
  EEA21060.1  31 TDIEVHISHCGICGTDLHTLRS-GWSPTDYPCVVGHEIIGTVVRIGSGVATlasspasrqIRVGDRVGIGAQMGTYNARYADK 112
                 6899*****************9.69*************************999****************99999888777665 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.1   0.0   4.7e-13   1.4e-09       1     128 [.     208     330 ..     208     335 .. 0.82

  Alignments for each domain:
  == domain 1  score: 39.1 bits;  conditional E-value: 4.7e-13
                   TT-SEEEETT.STTHHHHH-TT-EEEEEES-H..HHHH.HHHHHHEEEEEEEEE----..S-EEE-CHHHCTTT-EEEE--GGG...-.-HHHHHHH CS
  ADH_zinc_N_2   1 lGAdevidyr.tedfeaatggegvDvvldtvg..gealleaslkvlpggGrlvsiggpp.lsaallkpakkrkgrsvkyeflfsmkasaqadileel 93 
                   lGAd +i  + ++ ++  t +++ D++++tv+  +   l++ l++l+ gG++v++g+p     +l+++++ +k+ +++ + + s     + d ++e+
    EEA21060.1 208 LGADLFIATEeDKKWA-RTYSRSLDLIICTVDspK-LPLSQYLRLLRVGGTFVQVGAPEgPLPGLPAWSLIQKEVQITGSNIGS-----PDD-IREM 296
                   8******555588887.455888*********743.3359999***999*******6544666777777777777777777763.....778.**** PP

                   HHHHHHHH----EEEEEEGGGHHHHHHHHHSS--S CS
  ADH_zinc_N_2  94 aalieeGklrpvvdrvfpleeaaeAhrylesgrar 128
                   ++l +e+++ p ++   p+++++ A++++ +g+ar
    EEA21060.1 297 LQLAAEKRVYPWIQ-KRPMSDVNAALADMDAGKAR 330
                   *************8.69***************998 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   0.1     2e-07   0.00061      35      76 ..     163     204 ..     154     216 .. 0.85

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 2e-07
                   TTSEEEEES-SHHHHHHHHHHHHTT-.EEEEESSSHHHHHCHH CS
  2-Hacid_dh_C  35 sgktvGiiGlGrIGqavakrlkafgm.kviaydrskkkeeeee 76 
                    gktvGiiG+G +G+  +  +ka+g+ +v+a++r+ +k++ ++
    EEA21060.1 163 PGKTVGIIGVGGLGHLGILFAKALGCeRVVAISRTSSKRK-DA 204
                   59************************88999999988666.33 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.8      0.48   1.4e+03      29      45 ..      69      85 ..      62      99 .. 0.72
   2 !   18.1   0.0   4.4e-07    0.0013      30     102 ..     166     240 ..     158     265 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.48
                 -EEEEESTSHHHHHHHH CS
  AlaDh_PNT_C 29 akvlviGgGvaGlqAia 45
                 ++v+ iG Gva l++  
   EEA21060.1 69 GTVVRIGSGVATLASSP 85
                 56777888888887644 PP

  == domain 2  score: 18.1 bits;  conditional E-value: 4.4e-07
                  EEEEESTSHHHHHHHHHHHHTT-E..EEEEESSHHHHHHHHHTTTCECEEHCHHHHHHHHHHHH-SEEEE---BT CS
  AlaDh_PNT_C  30 kvlviGgGvaGlqAiatakglgak..VtvlDvrparleqleslgakfvevlksqeellaeavkeadvvigtvlip 102
                  +v +iG+G  G   i  ak+lg +  V +  ++++r+  +e lga  + + +++++  +   ++ d++i+tv  p
   EEA21060.1 166 TVGIIGVGGLGHLGILFAKALGCErvVAISRTSSKRKDAVEGLGADLFIATEEDKKWARTYSRSLDLIICTVDSP 240
                  467****************9996433888999999999********88888889999999999********9765 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   9.6e-05      0.29      12      87 ..     164     241 ..     157     247 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 9.6e-05
                   T-EEEEES-SHHHHHHHHHHHCCT-CEEEEEESSHHHHHHHHHHHT.ET-EEEEGCG..HHHHHHT-SEEEE-SSSSS CS
  Shikimate_DH  12 ekkvlliGaGemaelvakhLlakgvkkvvvaNRtlerakelaeelkgeeiealklee..lkellaeadvvisatasee 87 
                   +k+v +iG G +++l +    a g+++vv + Rt ++ k+ +e l+++ + a++ ++   +++ ++ d++i+ + s++
    EEA21060.1 164 GKTVGIIGVGGLGHLGILFAKALGCERVVAISRTSSKRKDAVEGLGADLFIATEEDKkwARTYSRSLDLIICTVDSPK 241
                   6899**********999999999*********************9888666665554335677788888888887776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (346 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       302  (0.0168442); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.46u 0.30s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 2331.41
//
Query:       EEA21061.1  [L=383]
Description: integral membrane protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (383 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       633  (0.0353059); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 2640.22
//
Query:       EEA21062.1  [L=75]
Description: vacuolar ATP synthase subunit e, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    6.5e-23   81.0   3.4    7.2e-23   80.8   3.4    1.0  1  ATP_synt_H  ATP synthase subunit H
  ------ inclusion threshold ------
      0.052   13.7   0.5      0.056   13.6   0.5    1.1  1  Pox_A14     Poxvirus virion envelope protein A14
      0.062   12.9   2.2      0.065   12.9   2.2    1.1  1  DUF4131     Domain of unknown function (DUF4131)
       0.19   11.2   0.4       0.22   11.0   0.4    1.0  1  DUF1129     Protein of unknown function (DUF1129)
       0.37   10.7   4.2       0.69    9.9   4.2    1.5  1  Caveolin    Caveolin
        5.5    6.8   5.5       0.51   10.1   0.8    1.7  2  HCV_NS4a    Hepatitis C virus non-structural protein NS4a


Domain annotation for each model (and alignments):
>> ATP_synt_H  ATP synthase subunit H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.8   3.4   2.4e-26   7.2e-23       2      61 ..       7      66 ..       6      67 .. 0.97

  Alignments for each domain:
  == domain 1  score: 80.8 bits;  conditional E-value: 2.4e-26
                THHHHHHHHHHHTCSCSSS-S.TTHHHHHHHHHHHHHHHHHTCHHTSSSS-SS---XXSX CS
  ATP_synt_H  2 ilvgtiifavlgvvatfvvpkgenrglirvlviltavccWlfWlcvYlaQmnPLiaPils 61
                +++g+++ ++++++a+f++pkg+n++++r+++il++  c+++W++++laQ++PLi+P++s
  EEA21062.1  7 VIIGLVFAILASLCAWFFAPKGDNQTVWRSSLILAFSACYIMWAITFLAQWHPLIVPTRS 66
                89********************************************************97 PP

>> Pox_A14  Poxvirus virion envelope protein A14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.5   1.9e-05     0.056      15      58 ..       7      48 ..       2      69 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 1.9e-05
     Pox_A14 15 liaGiiLLilacifafvdfskststtdkawralsivsFilgivi 58
                +i+G++  ila ++a++   k  +  +++wr+  i++F    ++
  EEA21062.1  7 VIIGLVFAILASLCAWFFAPKGDN--QTVWRSSLILAFSACYIM 48
                899*************96666666..459***999999665544 PP

>> DUF4131  Domain of unknown function (DUF4131)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   2.2   2.2e-05     0.065       8      49 ..       7      57 ..       2      70 .. 0.53

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.2e-05
     DUF4131  8 vllalllllllllllllrr.........rprrrvllllllllllallgfal 49
                v+++l++++l+ l++++           r +   +++++++++++++ +++
  EEA21062.1  7 VIIGLVFAILASLCAWFFApkgdnqtvwRSSLILAFSACYIMWAITFLAQW 57
                555555555555555555567665544444444444444444444444444 PP

>> DUF1129  Protein of unknown function (DUF1129)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.4   7.3e-05      0.22     120     174 ..       6      61 ..       4      68 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 7.3e-05
     DUF1129 120 alvgGlamvlvyrlltre.kkkkkrpplwkrllilllllvvwlvlftlvallpavi 174
                 +++ Gl++ +++ l     ++k + + +w++ lil+++   ++ ++t++a   + i
  EEA21062.1   6 SVIIGLVFAILASLCAWFfAPKGDNQTVWRSSLILAFSACYIMWAITFLAQWHPLI 61 
                 78999999999999988889*******************99999999988766655 PP

>> Caveolin  Caveolin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   4.2   0.00023      0.69      69     107 ..       5      43 ..       1      62 [. 0.79

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00023
    Caveolin  69 lalilgilfallsalhiwlvvPlvklllielkliqkvws 107
                  ++i+g++fa+l++l  w+  P     ++  +++   +s
  EEA21062.1   5 ASVIIGLVFAILASLCAWFFAPKGDNQTVWRSSLILAFS 43 
                 589*******************88777766666555555 PP

>> HCV_NS4a  Hepatitis C virus non-structural protein NS4a
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.8   0.00017      0.51       2      20 ..       5      23 ..       4      26 .. 0.91
   2 ?   -2.1   0.3       1.1   3.3e+03       8      19 ..      38      49 ..      38      57 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00017
    HCV_NS4a  2 pvvlvGlalAglAiyaltt 20
                + v++Gl+ A lA ++ ++
  EEA21062.1  5 ASVIIGLVFAILASLCAWF 23
                679**************97 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.1
    HCV_NS4a  8 lalAglAiyalt 19
                l+lA  A y  +
  EEA21062.1 38 LILAFSACYIMW 49
                577877777666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (75 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       780  (0.0435049); expected 358.6 (0.02)
Passed bias filter:                      492  (0.0274416); expected 358.6 (0.02)
Passed Vit filter:                        78  (0.00435049); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.47u 0.33s 00:00:00.80 Elapsed: 00:00:00.50
# Mc/sec: 450.82
//
Query:       EEA21063.1  [L=75]
Description: vacuolar ATP synthase subunit e, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    6.5e-23   81.0   3.4    7.2e-23   80.8   3.4    1.0  1  ATP_synt_H  ATP synthase subunit H
  ------ inclusion threshold ------
      0.052   13.7   0.5      0.056   13.6   0.5    1.1  1  Pox_A14     Poxvirus virion envelope protein A14
      0.062   12.9   2.2      0.065   12.9   2.2    1.1  1  DUF4131     Domain of unknown function (DUF4131)
       0.19   11.2   0.4       0.22   11.0   0.4    1.0  1  DUF1129     Protein of unknown function (DUF1129)
       0.37   10.7   4.2       0.69    9.9   4.2    1.5  1  Caveolin    Caveolin
        5.5    6.8   5.5       0.51   10.1   0.8    1.7  2  HCV_NS4a    Hepatitis C virus non-structural protein NS4a


Domain annotation for each model (and alignments):
>> ATP_synt_H  ATP synthase subunit H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.8   3.4   2.4e-26   7.2e-23       2      61 ..       7      66 ..       6      67 .. 0.97

  Alignments for each domain:
  == domain 1  score: 80.8 bits;  conditional E-value: 2.4e-26
                THHHHHHHHHHHTCSCSSS-S.TTHHHHHHHHHHHHHHHHHTCHHTSSSS-SS---XXSX CS
  ATP_synt_H  2 ilvgtiifavlgvvatfvvpkgenrglirvlviltavccWlfWlcvYlaQmnPLiaPils 61
                +++g+++ ++++++a+f++pkg+n++++r+++il++  c+++W++++laQ++PLi+P++s
  EEA21063.1  7 VIIGLVFAILASLCAWFFAPKGDNQTVWRSSLILAFSACYIMWAITFLAQWHPLIVPTRS 66
                89********************************************************97 PP

>> Pox_A14  Poxvirus virion envelope protein A14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.5   1.9e-05     0.056      15      58 ..       7      48 ..       2      69 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 1.9e-05
     Pox_A14 15 liaGiiLLilacifafvdfskststtdkawralsivsFilgivi 58
                +i+G++  ila ++a++   k  +  +++wr+  i++F    ++
  EEA21063.1  7 VIIGLVFAILASLCAWFFAPKGDN--QTVWRSSLILAFSACYIM 48
                899*************96666666..459***999999665544 PP

>> DUF4131  Domain of unknown function (DUF4131)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   2.2   2.2e-05     0.065       8      49 ..       7      57 ..       2      70 .. 0.53

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.2e-05
     DUF4131  8 vllalllllllllllllrr.........rprrrvllllllllllallgfal 49
                v+++l++++l+ l++++           r +   +++++++++++++ +++
  EEA21063.1  7 VIIGLVFAILASLCAWFFApkgdnqtvwRSSLILAFSACYIMWAITFLAQW 57
                555555555555555555567665544444444444444444444444444 PP

>> DUF1129  Protein of unknown function (DUF1129)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.4   7.3e-05      0.22     120     174 ..       6      61 ..       4      68 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 7.3e-05
     DUF1129 120 alvgGlamvlvyrlltre.kkkkkrpplwkrllilllllvvwlvlftlvallpavi 174
                 +++ Gl++ +++ l     ++k + + +w++ lil+++   ++ ++t++a   + i
  EEA21063.1   6 SVIIGLVFAILASLCAWFfAPKGDNQTVWRSSLILAFSACYIMWAITFLAQWHPLI 61 
                 78999999999999988889*******************99999999988766655 PP

>> Caveolin  Caveolin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   4.2   0.00023      0.69      69     107 ..       5      43 ..       1      62 [. 0.79

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00023
    Caveolin  69 lalilgilfallsalhiwlvvPlvklllielkliqkvws 107
                  ++i+g++fa+l++l  w+  P     ++  +++   +s
  EEA21063.1   5 ASVIIGLVFAILASLCAWFFAPKGDNQTVWRSSLILAFS 43 
                 589*******************88777766666555555 PP

>> HCV_NS4a  Hepatitis C virus non-structural protein NS4a
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.8   0.00017      0.51       2      20 ..       5      23 ..       4      26 .. 0.91
   2 ?   -2.1   0.3       1.1   3.3e+03       8      19 ..      38      49 ..      38      57 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00017
    HCV_NS4a  2 pvvlvGlalAglAiyaltt 20
                + v++Gl+ A lA ++ ++
  EEA21063.1  5 ASVIIGLVFAILASLCAWF 23
                679**************97 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.1
    HCV_NS4a  8 lalAglAiyalt 19
                l+lA  A y  +
  EEA21063.1 38 LILAFSACYIMW 49
                577877777666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (75 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       780  (0.0435049); expected 358.6 (0.02)
Passed bias filter:                      492  (0.0274416); expected 358.6 (0.02)
Passed Vit filter:                        78  (0.00435049); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 524.91
//
Query:       EEA21064.1  [L=300]
Description: BAR domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.9e-63  213.7   0.5    4.1e-63  213.2   0.5    1.2  1  BAR_2     Bin/amphiphysin/Rvs domain for vesicular traffickin
      3e-23   82.7   4.5    6.8e-22   78.3   4.5    2.0  1  BAR       BAR domain
    0.00033   20.4   0.7      0.036   13.8   0.0    2.2  2  BAR_3     BAR domain of APPL family


Domain annotation for each model (and alignments):
>> BAR_2  Bin/amphiphysin/Rvs domain for vesicular trafficking
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  213.2   0.5   6.9e-67   4.1e-63       3     283 ..      16     283 ..      14     289 .. 0.92

  Alignments for each domain:
  == domain 1  score: 213.2 bits;  conditional E-value: 6.9e-67
       BAR_2   3 lsikkkttrllqeklgqvkdiskLPkqYleLEkkvDslekvykrlllvtktyevegYDYPpnltesisdwwksigaklkelknvssleedeivllgkkk 101
                 ++++++t+++++e+lgq+++  +LP +YleLEk+vD+l++v ++ll vt+ y +e+YDYPpn++es++d++++i++k++ l+++ss+ e++ +l +  +
  EEA21064.1  16 TPFAARTQQFVKEQLGQADEKTQLPDDYLELEKRVDALKQVHQKLLSVTSQYSNEAYDYPPNIRESFNDLGRTISEKVNLLSHASSPAEAQAALTAPPS 114
                 79******************************************************************************************8854443 PP

       BAR_2 102 kekskeekesqatsallprtlaqalskaakdsslilqeleekdedlepLikvleqvssaykeiaeakleqDslivkefnkkLeellnqefkkvhelrkk 200
                 ++              +p+t+ +a+++a+   s+ +    +++ +++pL+ +le+++ a +++ ea+l qD  i++ f +  +++ln+++  + + r++
  EEA21064.1 115 AK------P-------QPKTFSHAIARASLSGSQLIA---QTSPAEDPLSTALEKYALALEKVGEARLAQDAQIQSRFLAGWNTTLNTNLTFATKARRN 197
                 33......3.......6*************9994544...4577789**************************************************** PP

       BAR_2 201 VeesRlkfdtlrseveek...ekpeteeedkklleklEDefvsateeAvvvmkeildssklisllklfqkaqleYfekcvkkleel 283
                 Ve+sRl +d ++ + ++    +  +  e+ + ++e++EDefv  teeAv vmk++ld  + + +l  +++aqleY++++ + l el
  EEA21064.1 198 VENSRLSLDSIKAKKKAAaggDLDNISEDARIEIEQAEDEFVGQTEEAVAVMKNVLDTPEPLRNLADLIAAQLEYHKRAYEILSEL 283
                 *************99997665334445568999*********************************************99888776 PP

>> BAR  BAR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.3   4.5   1.1e-25   6.8e-22       6     235 ..      20     285 ..      11     288 .. 0.78

  Alignments for each domain:
  == domain 1  score: 78.3 bits;  conditional E-value: 1.1e-25
         BAR   6 nRasqlleekvgka.ekTkLDedFeelerrldvteklieklvkelkeylqanpga...rakqivlekl..............................k 70 
                 +R++q ++e +g+a ekT+L +d+ ele+r+d ++++ +kl++ +++y+     +     +++  ++l                              k
  EEA21064.1  20 ARTQQFVKEQLGQAdEKTQLPDDYLELEKRVDALKQVHQKLLSVTSQYSNEAYDYppnIRESF--NDLgrtisekvnllshasspaeaqaaltappsaK 116
                 79**********9836777*****************************994433311022222..3335555555566666655555555555555553 PP

         BAR  71 eqplelLaesmieagkelgedssfg...............................kalekygeavkklaqteeelekrvetnfldplrellekefkei 138
                                                                          aleky+ a++k++++    +++++++fl   ++ l++ ++  
  EEA21064.1 117 ------------------------PqpktfshaiaraslsgsqliaqtspaedplsTALEKYALALEKVGEARLAQDAQIQSRFLAGWNTTLNTNLTFA 191
                 ........................04444444455555555555555555555555******************************************* PP

         BAR 139 qkerkklehkrlDyDaakarlkklktkkskkakde.ekaeeelrkAqqkfeesneelkaeLpnllalevefvnqlqafveaqldfhkqaaqlleqlqq 235
                  k+r++ e+ rl +D+ ka+ k +   +  +     e a+ e+++A+++f  + ee+ a ++n+l++  e +++l +++ aql++hk+a+++l++l +
  EEA21064.1 192 TKARRNVENSRLSLDSIKAKKKAAAGGDLDN---IsEDARIEIEQAEDEFVGQTEEAVAVMKNVLDT-PEPLRNLADLIAAQLEYHKRAYEILSELAP 285
                 **********************999544433...35****************************665.4556**********************9976 PP

>> BAR_3  BAR domain of APPL family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.4   0.2    0.0022        13      43      88 ..       6      65 ..       1      98 [. 0.67
   2 !   13.8   0.0     6e-06     0.036      69     220 ..     144     293 ..     118     299 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.0022
       BAR_3 43 eagkaysaaqkqfaqsLrelkkes..kgdeetd............esLkkfsellqelen 88
                + gk+++a++  fa + +++ ke+  + de+t+            ++Lk++++ l  + +
  EEA21064.1  6 AFGKNFNAQFTPFAARTQQFVKEQlgQADEKTQlpddylelekrvDALKQVHQKLLSVTS 65
                556777777777777777777777666666666665555555444444444444444333 PP

  == domain 2  score: 13.8 bits;  conditional E-value: 6e-06
       BAR_3  69 deetdesLkkfsellqelenehtilldqaqrsikkpLekFrkedlkevkekkkkFdkesekleaaleknaqlskkkkeseleeadnelkatrkkfhqas 167
                 ++ ++++L+k + +l+++ + +     q+q+++ +  ++ +  +l+ +++++++ + ++ +l++  +k  ++     ++  e+a  e+++++ +f  + 
  EEA21064.1 144 EDPLSTALEKYALALEKVGEARLAQDAQIQSRFLAGWNTTLNTNLTFATKARRNVENSRLSLDSIKAKKKAAAGGDLDNISEDARIEIEQAEDEFVGQT 242
                 4455688999999999999999999999999999999999999***999*************999999988888878888889**************** PP

       BAR_3 168 ldyvlqinelqerkkfeiletllsfmqaqltFfhqGyelfkdlepfmkeLsaq 220
                  + v  ++ + +    e l +l  ++ aql + +  ye++++l p+   L+ +
  EEA21064.1 243 EEAVAVMKNVLD--TPEPLRNLADLIAAQLEYHKRAYEILSELAPVVDGLQVE 293
                 *****9999986..5799****************************9998865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (300 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       838  (0.0467399); expected 358.6 (0.02)
Passed bias filter:                      498  (0.0277762); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.30s 00:00:00.83 Elapsed: 00:00:00.47
# Mc/sec: 1929.91
//
Query:       EEA21065.1  [L=305]
Description: BAR domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-63  213.6   0.5    4.4e-63  213.1   0.5    1.2  1  BAR_2     Bin/amphiphysin/Rvs domain for vesicular traffickin
    3.2e-23   82.6   4.5    7.4e-22   78.2   4.5    2.0  1  BAR       BAR domain
    0.00023   20.9   0.6      0.028   14.1   0.0    2.2  2  BAR_3     BAR domain of APPL family


Domain annotation for each model (and alignments):
>> BAR_2  Bin/amphiphysin/Rvs domain for vesicular trafficking
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  213.1   0.5   7.3e-67   4.4e-63       3     283 ..      16     283 ..      14     289 .. 0.92

  Alignments for each domain:
  == domain 1  score: 213.1 bits;  conditional E-value: 7.3e-67
       BAR_2   3 lsikkkttrllqeklgqvkdiskLPkqYleLEkkvDslekvykrlllvtktyevegYDYPpnltesisdwwksigaklkelknvssleedeivllgkkk 101
                 ++++++t+++++e+lgq+++  +LP +YleLEk+vD+l++v ++ll vt+ y +e+YDYPpn++es++d++++i++k++ l+++ss+ e++ +l +  +
  EEA21065.1  16 TPFAARTQQFVKEQLGQADEKTQLPDDYLELEKRVDALKQVHQKLLSVTSQYSNEAYDYPPNIRESFNDLGRTISEKVNLLSHASSPAEAQAALTAPPS 114
                 79******************************************************************************************8854443 PP

       BAR_2 102 kekskeekesqatsallprtlaqalskaakdsslilqeleekdedlepLikvleqvssaykeiaeakleqDslivkefnkkLeellnqefkkvhelrkk 200
                 ++              +p+t+ +a+++a+   s+ +    +++ +++pL+ +le+++ a +++ ea+l qD  i++ f +  +++ln+++  + + r++
  EEA21065.1 115 AK------P-------QPKTFSHAIARASLSGSQLIA---QTSPAEDPLSTALEKYALALEKVGEARLAQDAQIQSRFLAGWNTTLNTNLTFATKARRN 197
                 33......3.......6*************9994544...4577789**************************************************** PP

       BAR_2 201 VeesRlkfdtlrseveek...ekpeteeedkklleklEDefvsateeAvvvmkeildssklisllklfqkaqleYfekcvkkleel 283
                 Ve+sRl +d ++ + ++    +  +  e+ + ++e++EDefv  teeAv vmk++ld  + + +l  +++aqleY++++ + l el
  EEA21065.1 198 VENSRLSLDSIKAKKKAAaggDLDNISEDARIEIEQAEDEFVGQTEEAVAVMKNVLDTPEPLRNLADLIAAQLEYHKRAYEILSEL 283
                 *************99997665334445568999*********************************************99888776 PP

>> BAR  BAR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.2   4.5   1.2e-25   7.4e-22       6     235 ..      20     285 ..      11     288 .. 0.78

  Alignments for each domain:
  == domain 1  score: 78.2 bits;  conditional E-value: 1.2e-25
         BAR   6 nRasqlleekvgka.ekTkLDedFeelerrldvteklieklvkelkeylqanpga...rakqivlekl..............................k 70 
                 +R++q ++e +g+a ekT+L +d+ ele+r+d ++++ +kl++ +++y+     +     +++  ++l                              k
  EEA21065.1  20 ARTQQFVKEQLGQAdEKTQLPDDYLELEKRVDALKQVHQKLLSVTSQYSNEAYDYppnIRESF--NDLgrtisekvnllshasspaeaqaaltappsaK 116
                 79**********9836777*****************************994433311022222..3335555555566666655555555555555553 PP

         BAR  71 eqplelLaesmieagkelgedssfg...............................kalekygeavkklaqteeelekrvetnfldplrellekefkei 138
                                                                          aleky+ a++k++++    +++++++fl   ++ l++ ++  
  EEA21065.1 117 ------------------------PqpktfshaiaraslsgsqliaqtspaedplsTALEKYALALEKVGEARLAQDAQIQSRFLAGWNTTLNTNLTFA 191
                 ........................04444444455555555555555555555555******************************************* PP

         BAR 139 qkerkklehkrlDyDaakarlkklktkkskkakde.ekaeeelrkAqqkfeesneelkaeLpnllalevefvnqlqafveaqldfhkqaaqlleqlqq 235
                  k+r++ e+ rl +D+ ka+ k +   +  +     e a+ e+++A+++f  + ee+ a ++n+l++  e +++l +++ aql++hk+a+++l++l +
  EEA21065.1 192 TKARRNVENSRLSLDSIKAKKKAAAGGDLDN---IsEDARIEIEQAEDEFVGQTEEAVAVMKNVLDT-PEPLRNLADLIAAQLEYHKRAYEILSELAP 285
                 **********************999544433...35****************************665.4556**********************9976 PP

>> BAR_3  BAR domain of APPL family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.4   0.2    0.0022        13      43      88 ..       6      65 ..       1      98 [. 0.67
   2 !   14.1   0.0   4.6e-06     0.028      69     221 ..     144     294 ..     118     304 .. 0.87

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.0022
       BAR_3 43 eagkaysaaqkqfaqsLrelkkes..kgdeetd............esLkkfsellqelen 88
                + gk+++a++  fa + +++ ke+  + de+t+            ++Lk++++ l  + +
  EEA21065.1  6 AFGKNFNAQFTPFAARTQQFVKEQlgQADEKTQlpddylelekrvDALKQVHQKLLSVTS 65
                556777777777777777777777666666666665555555444444444444444333 PP

  == domain 2  score: 14.1 bits;  conditional E-value: 4.6e-06
       BAR_3  69 deetdesLkkfsellqelenehtilldqaqrsikkpLekFrkedlkevkekkkkFdkesekleaaleknaqlskkkkeseleeadnelkatrkkfhqas 167
                 ++ ++++L+k + +l+++ + +     q+q+++ +  ++ +  +l+ +++++++ + ++ +l++  +k  ++     ++  e+a  e+++++ +f  + 
  EEA21065.1 144 EDPLSTALEKYALALEKVGEARLAQDAQIQSRFLAGWNTTLNTNLTFATKARRNVENSRLSLDSIKAKKKAAAGGDLDNISEDARIEIEQAEDEFVGQT 242
                 4455688999999999999999999999999999999999999***999*************9999999888888788888899*************** PP

       BAR_3 168 ldyvlqinelqerkkfeiletllsfmqaqltFfhqGyelfkdlepfmkeLsaql 221
                  + v  ++ + +    e l +l  ++ aql + +  ye++++l p+   L+ + 
  EEA21065.1 243 EEAVAVMKNVLD--TPEPLRNLADLIAAQLEYHKRAYEILSELAPVVDGLQVEQ 294
                 *****9999986..5799****************************99998654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (305 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       858  (0.0478554); expected 358.6 (0.02)
Passed bias filter:                      503  (0.0280551); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 2136.06
//
Query:       EEA21066.1  [L=495]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (495 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       503  (0.0280551); expected 358.6 (0.02)
Passed bias filter:                      279  (0.0155614); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 3447.54
//
Query:       EEA21067.1  [L=369]
Description: alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.1e-25   87.3   0.1    1.4e-24   86.6   0.1    1.3  1  ADH_zinc_N    Zinc-binding dehydrogenase
    5.4e-17   61.6   0.8    9.6e-17   60.8   0.8    1.4  1  ADH_N         Alcohol dehydrogenase GroES-like domain
    1.5e-06   29.3   0.0    2.6e-06   28.5   0.0    1.4  1  ADH_zinc_N_2  Zinc-binding dehydrogenase
  ------ inclusion threshold ------
        1.1    9.8   5.7       0.11   12.9   1.3    1.6  2  TNFR_c6       TNFR/NGFR cysteine-rich region
        5.6    7.2   7.1        7.2    6.8   0.3    2.5  2  SR1P          SR1 protein


Domain annotation for each model (and alignments):
>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.6   0.1   3.8e-28   1.4e-24       1     127 [.     200     329 ..     200     332 .. 0.94

  Alignments for each domain:
  == domain 1  score: 86.6 bits;  conditional E-value: 3.8e-28
                 HHHHHHHHHHHHTT-.EEEEEESSHHHHHHHHHTTESEEEETTTC.HHHHHHHHHTTTSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSCTSSEEEE CS
  ADH_zinc_N   1 gvGlaavqlAkalGa.eviavdsseeklelakklGadevinykea.dlverikeltggegvdvvfecvGsgatleaalkllkpgGrlvvvGggkgeeef 97 
                 g+G+++vq+A  ++  +via+d  ++k++l  + Ga+++i+ k++ d+ +r++eltggeg+++ + ++G++a++e+a ++++  G++v+vG++ ++ e+
  EEA21067.1 200 GLGHIGVQIASRIKHyRVIAIDTGDDKRQLSLDCGAEAFIDFKTEpDVASRVHELTGGEGAHATIVVPGTKAAFEMAPSVVRNMGTIVCVGLPRNDVEL 298
                 89*********99999****************************************************************************9999996 PP

                 EHHH..HHHTT-EEEEE-SSCHHHHHHHHHHH CS
  ADH_zinc_N  98 dlrn..lllkeksilGsllgslreefkealdl 127
                 +++   ++++ +si+Gs +gs  e++ e+l+ 
  EEA21067.1 299 PISAtiCAARGISIIGSSVGS-EEQMTELLQH 329
                 66664377*************.9**9999885 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.8   0.8   2.7e-20   9.6e-17       1     107 [.      35     145 ..      35     147 .. 0.87

  Alignments for each domain:
  == domain 1  score: 60.8 bits;  conditional E-value: 2.7e-20
                 TTEEEEEEEEEEE-HHHH..HHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS..--TT-EEEE-SEEE.-SSSHHHHTT-GGG-TTBEETTTSS-SS CS
       ADH_N   1 pgevlikvkaagiCgsDl..hilkggkelevklplilGHEivGeveevgpevkk..lkvGdrVvveplis.cgeCaaCkegeenlCeeakllgvsldGg 94 
                 p+evl+k++++g+C+       ++      ++++ ++GHE +G++ ++   +     +vG+rV v++l+s c eC+ C++g+++ C++++ ++ +++G+
  EEA21067.1  35 PNEVLVKLSCTGLCNGGTshSEVRA-VLNWASYNPVIGHEGIGTIIKTHTTLAPsvASVGERVGVKWLYSaCRECSVCRKGYYHNCARQANTSRHVPGT 132
                 689***********76661145554.4455566679***********9999988889***********999**************************** PP

                 SBSEEEECGGGEE CS
       ADH_N  95 faeyvvvpekklv 107
                 +++yvv+++++l 
  EEA21067.1 133 LQQYVVADARFLT 145
                 ********99886 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.5   0.0   7.3e-10   2.6e-06       2     133 .]     234     365 ..     233     365 .. 0.79

  Alignments for each domain:
  == domain 1  score: 28.5 bits;  conditional E-value: 7.3e-10
                   T-SEEEETT.STTHH....HHH-TT-EEEEEES-HHHHH.HHHHHHEEEEEEEEE----.S-EEE-CHHHCTTT-EEEE--GGG...-.-HHHHHHH CS
  ADH_zinc_N_2   2 GAdevidyr.tedfe....aatggegvDvvldtvggealleaslkvlpggGrlvsiggpplsaallkpakkrkgrsvkyeflfsmkasaqadileel 93 
                   GA+ +id + ++d++    + tggeg  + +   g++a++e + +v+++ G++v++g p  ++++  p +    +++ ++ + s + +  ++ ++el
    EEA21067.1 234 GAEAFIDFKtEPDVAsrvhELTGGEGAHATIVVPGTKAAFEMAPSVVRNMGTIVCVGLP--RNDVELPISATICAARGISIIGS-SVGSEEQ-MTEL 326
                   99999*999899999***999*99*9999999999777769999999888*******75..33333333323333333333332.2233566.**** PP

                   HHHHHHHH----EEEEEEGGGHHHHHHHHHSS--SSEEEE CS
  ADH_zinc_N_2  94 aalieeGklrpvvdrvfpleeaaeAhrylesgrarGKiVl 133
                   ++   +G ++pvv  v+++e+aa  +r+    + +GK+V+
    EEA21067.1 327 LQHALAGLINPVVK-VYEFEDAASLIRKFIDDAITGKVVV 365
                   *************7.************************8 PP

>> TNFR_c6  TNFR/NGFR cysteine-rich region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.2       3.9   1.4e+04      17      25 ..      43      52 ..      42      54 .. 0.75
   2 ?   12.9   1.3   3.1e-05      0.11      11      37 ..     101     125 ..      98     126 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 3.9
                EEE-.BGCTE CS
     TNFR_c6 17 pCtr.Cppgq 25
                +Ct  C+ g+
  EEA21067.1 43 SCTGlCNGGT 52
                6888898876 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 3.1e-05
                 CTCSEEEEE-BGCTEEECC--BTTC-- CS
     TNFR_c6  11 nskeClpCtrCppgqvvlrpCtptsdt 37 
                  ++ C+ C++C++g +   +C + ++t
  EEA21067.1 101 LYSACRECSVCRKGYYH--NCARQANT 125
                 5556*******999886..******99 PP

>> SR1P  SR1 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.3     0.002       7.2      20      31 ..      97     108 ..      94     114 .. 0.73
   2 ?    2.6   1.8     0.041   1.5e+02       1       6 [.     283     288 ..     283     289 .. 0.96

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.002
        SR1P  20 kVttLYgtCnqc 31 
                 +V+ LY+ C +c
  EEA21067.1  97 GVKWLYSACREC 108
                 69*******944 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.041
        SR1P   1 MGtIvC 6  
                 MGtIvC
  EEA21067.1 283 MGTIVC 288
                 ****** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (369 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       457  (0.0254894); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 2509.71
//
Query:       EEA21068.1  [L=364]
Description: alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.9e-25   87.3   0.1    1.3e-24   86.6   0.1    1.3  1  ADH_zinc_N    Zinc-binding dehydrogenase
    2.8e-19   69.0   0.7    4.9e-19   68.2   0.7    1.4  1  ADH_N         Alcohol dehydrogenase GroES-like domain
    1.5e-06   29.3   0.0    2.5e-06   28.6   0.0    1.4  1  ADH_zinc_N_2  Zinc-binding dehydrogenase
  ------ inclusion threshold ------
      0.052   14.0   1.3       0.11   12.9   1.3    1.5  1  TNFR_c6       TNFR/NGFR cysteine-rich region
        5.5    7.2   7.1        7.1    6.8   0.3    2.5  2  SR1P          SR1 protein


Domain annotation for each model (and alignments):
>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.6   0.1   3.7e-28   1.3e-24       1     127 [.     195     324 ..     195     327 .. 0.94

  Alignments for each domain:
  == domain 1  score: 86.6 bits;  conditional E-value: 3.7e-28
                 HHHHHHHHHHHHTT-.EEEEEESSHHHHHHHHHTTESEEEETTTC.HHHHHHHHHTTTSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSCTSSEEEE CS
  ADH_zinc_N   1 gvGlaavqlAkalGa.eviavdsseeklelakklGadevinykea.dlverikeltggegvdvvfecvGsgatleaalkllkpgGrlvvvGggkgeeef 97 
                 g+G+++vq+A  ++  +via+d  ++k++l  + Ga+++i+ k++ d+ +r++eltggeg+++ + ++G++a++e+a ++++  G++v+vG++ ++ e+
  EEA21068.1 195 GLGHIGVQIASRIKHyRVIAIDTGDDKRQLSLDCGAEAFIDFKTEpDVASRVHELTGGEGAHATIVVPGTKAAFEMAPSVVRNMGTIVCVGLPRNDVEL 293
                 89*********99999****************************************************************************9999996 PP

                 EHHH..HHHTT-EEEEE-SSCHHHHHHHHHHH CS
  ADH_zinc_N  98 dlrn..lllkeksilGsllgslreefkealdl 127
                 +++   ++++ +si+Gs +gs  e++ e+l+ 
  EEA21068.1 294 PISAtiCAARGISIIGSSVGS-EEQMTELLQH 324
                 66664377*************.9**9999885 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.2   0.7   1.4e-22   4.9e-19       1     107 [.      35     140 ..      35     142 .. 0.92

  Alignments for each domain:
  == domain 1  score: 68.2 bits;  conditional E-value: 1.4e-22
                 TTEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS..--TT-EEEE-SEEE.-SSSHHHHTT-GGG-TTBEETTTSS-SSSB CS
       ADH_N   1 pgevlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkk..lkvGdrVvveplis.cgeCaaCkegeenlCeeakllgvsldGgfa 96 
                 p+evl+k++++g+C+s++  + +     ++++ ++GHE +G++ ++   +     +vG+rV v++l+s c eC+ C++g+++ C++++ ++ +++G+++
  EEA21068.1  35 PNEVLVKLSCTGLCHSEVRAVLN----WASYNPVIGHEGIGTIIKTHTTLAPsvASVGERVGVKWLYSaCRECSVCRKGYYHNCARQANTSRHVPGTLQ 129
                 689***************99987....35555699**********9999988889***********999****************************** PP

                 SEEEECGGGEE CS
       ADH_N  97 eyvvvpekklv 107
                 +yvv+++++l 
  EEA21068.1 130 QYVVADARFLT 140
                 ******99886 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.6   0.0   7.1e-10   2.5e-06       2     133 .]     229     360 ..     228     360 .. 0.79

  Alignments for each domain:
  == domain 1  score: 28.6 bits;  conditional E-value: 7.1e-10
                   T-SEEEETT.STTHH....HHH-TT-EEEEEES-HHHHH.HHHHHHEEEEEEEEE----.S-EEE-CHHHCTTT-EEEE--GGG...-.-HHHHHHH CS
  ADH_zinc_N_2   2 GAdevidyr.tedfe....aatggegvDvvldtvggealleaslkvlpggGrlvsiggpplsaallkpakkrkgrsvkyeflfsmkasaqadileel 93 
                   GA+ +id + ++d++    + tggeg  + +   g++a++e + +v+++ G++v++g p  ++++  p +    +++ ++ + s + +  ++ ++el
    EEA21068.1 229 GAEAFIDFKtEPDVAsrvhELTGGEGAHATIVVPGTKAAFEMAPSVVRNMGTIVCVGLP--RNDVELPISATICAARGISIIGS-SVGSEEQ-MTEL 321
                   99999*999899999***999*99*9999999999777769999999888*******75..33333333323333333333332.2233566.**** PP

                   HHHHHHHH----EEEEEEGGGHHHHHHHHHSS--SSEEEE CS
  ADH_zinc_N_2  94 aalieeGklrpvvdrvfpleeaaeAhrylesgrarGKiVl 133
                   ++   +G ++pvv  v+++e+aa  +r+    + +GK+V+
    EEA21068.1 322 LQHALAGLINPVVK-VYEFEDAASLIRKFIDDAITGKVVV 360
                   *************7.************************8 PP

>> TNFR_c6  TNFR/NGFR cysteine-rich region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   1.3     3e-05      0.11      11      37 ..      96     120 ..      93     121 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 3e-05
                 CTCSEEEEE-BGCTEEECC--BTTC-- CS
     TNFR_c6  11 nskeClpCtrCppgqvvlrpCtptsdt 37 
                  ++ C+ C++C++g +   +C + ++t
  EEA21068.1  96 LYSACRECSVCRKGYYH--NCARQANT 120
                 5556*******999886..******99 PP

>> SR1P  SR1 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.3     0.002       7.1      20      31 ..      92     103 ..      89     109 .. 0.73
   2 ?    2.6   1.8      0.04   1.4e+02       1       6 [.     278     283 ..     278     284 .. 0.96

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.002
        SR1P  20 kVttLYgtCnqc 31 
                 +V+ LY+ C +c
  EEA21068.1  92 GVKWLYSACREC 103
                 69*******944 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.04
        SR1P   1 MGtIvC 6  
                 MGtIvC
  EEA21068.1 278 MGTIVC 283
                 ****** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (364 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       462  (0.0257683); expected 358.6 (0.02)
Passed bias filter:                      367  (0.0204696); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 2410.00
//
Query:       EEA21069.1  [L=424]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.3e-61  207.1   0.0    1.7e-52  178.6   0.0    2.3  2  Arv1      Arv1-like family


Domain annotation for each model (and alignments):
>> Arv1  Arv1-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  178.6   0.0   9.7e-57   1.7e-52       1     154 [.       3     159 ..       3     192 .. 0.88
   2 !   26.2   0.0   4.3e-10   7.7e-06     161     189 ..     252     280 ..     206     286 .. 0.85

  Alignments for each domain:
  == domain 1  score: 178.6 bits;  conditional E-value: 9.7e-57
        Arv1   1 iCieCgepvksLytkYskg.......nirltkCknCkkvaDkYvEfdnvilfiDllLlkpqaYrHllfNtlereeekfekikslirlvillllfevylt 92 
                 iCieC++pv++Lyt+Ysk+        +rlt+C++Ck++aDkYvE+dnv+lfiDl+L+kpq+YrHllfN+l r+++ f+  +s+irl++llllf+vylt
  EEA21069.1   3 ICIECSYPVSHLYTSYSKAddralgkGVRLTQCPRCKRFADKYVEHDNVVLFIDLVLIKPQVYRHLLFNQLGRDDKAFD--PSIIRLGVLLLLFDVYLT 99 
                 8******************************************************************************..****************** PP

        Arv1  93 wariekksesessslsaqaivlesakelkqylfflvlalletlvfhlsillllslesslsa.....l 154
                 wariek+s+ +s+sls+ +i++       qylffl+l    tl+ hl+++l  s+ s+ s+     l
  EEA21069.1 100 WARIEKSSTLASTSLSTAPIIV-------QYLFFLTLNASATLAHHLVVRLGASIISKRSQqtsssL 159
                 ******9999999999999999.......*********************99988777666443331 PP

  == domain 2  score: 26.2 bits;  conditional E-value: 4.3e-10
        Arv1 161 arlnalltalllssyaklfpilmlIWeyd 189
                  + na++tal++ss+ klfpilm+IW  +
  EEA21069.1 252 PSANAVSTALFVSSCPKLFPILMVIWGSK 280
                 5789**********************765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (424 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       731  (0.0407719); expected 358.6 (0.02)
Passed bias filter:                      461  (0.0257125); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 2949.80
//
Query:       EEA21070.1  [L=1043]
Description: C6 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      3e-14   52.6   8.8    4.3e-13   48.8   0.2    3.4  4  Fungal_trans_2  Fungal specific transcription factor domain
    3.2e-07   30.3  12.2    5.8e-07   29.5  12.2    1.4  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
        7.7    6.4  23.1         14    5.6  23.1    1.4  1  TFIIA           Transcription factor IIA, alpha/beta subunit


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -6.8   3.7         3   1.8e+04      51      78 ..     139     164 ..     131     165 .. 0.61
   2 !   48.8   0.2   7.2e-17   4.3e-13       5     130 ..     399     533 ..     396     555 .. 0.78
   3 !    6.5   0.0   0.00053       3.2     148     216 ..     628     693 ..     624     704 .. 0.91
   4 ?    1.2   0.0     0.021   1.3e+02     300     337 ..     909     946 ..     806     970 .. 0.74

  Alignments for each domain:
  == domain 1  score: -6.8 bits;  conditional E-value: 3
  Fungal_trans_2  51 qskgpkdslereakrykslalkelqeal 78 
                     q+++++   ++++++ + +al++ q+ l
      EEA21070.1 139 QQQQQQ--QQQQDQSISGQALNRQQRLL 164
                     233333..47888888888887777665 PP

  == domain 2  score: 48.8 bits;  conditional E-value: 7.2e-17
  Fungal_trans_2   5 yyldnvapllspvpes...snpfrkvllplalsnk.............allhallalsafhlqskgpkdslereakrykslalkelqealaelss 83 
                     ++ + +ap +s+  ++     pf    +p  ++               all+++la+s++h + +++++   +   ++++ al+ +++a   + +
      EEA21070.1 399 HFMHATAPAISIMERHnanPTPFFGGPVPASQQGLwsyimplkslehpALLQSILAISSLHIARLQQSH--FTITFKHYEYALRKVSKAVGLPLR 491
                     566666666666665555544444444444444444444444444445*********************..78999******************* PP

  Fungal_trans_2  84 tlsrnekykdiLaaiLllcsieissgdvsdwrvhLeaatsliksrgg 130
                     +++      ++Laa+Lll ++e+   d ++w  hL +a  l+k    
      EEA21070.1 492 RKQ-----VSTLAATLLLAFYEVTAADHTKWDRHLAGAAQLLKEIDF 533
                     ***.....**********************************98765 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.00053
  Fungal_trans_2 148 ifayldilssttlgrgpsfpseeyekllenkkeesdsgldplmGcsnslilliseisrLarekrsarkd 216
                     ++a +d ++s  +g++++ p e +  +  +    +   +d ++G  ++l+ll+++ ++ + + r+++ +
      EEA21070.1 628 WYAKQDFFQSMLSGNRLLTPIERWDAIPPR---AGLGKVDAIYGSWDHLVLLLARMMDFGYRDRKRKLQ 693
                     89999*************************...99999******************9998877777666 PP

  == domain 4  score: 1.2 bits;  conditional E-value: 0.021
  Fungal_trans_2 300 ellpsspvaiasLlWplFiaGceavdeddRdfvrrrle 337
                     +l p+ ++a++  ++ lF+aG+  +d  +Rd+  + l+
      EEA21070.1 909 NLNPNLGGAWIQATMTLFVAGIQYTDAIQRDWTVSTLQ 946
                     3334555578888999**********999999877666 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.5  12.2   9.7e-11   5.8e-07       1      36 [.      56      91 ..      56      92 .. 0.95

  Alignments for each domain:
  == domain 1  score: 29.5 bits;  conditional E-value: 9.7e-11
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfyses 36
                ++C +Crk+++KC ++kP C nC+k   +C+ y+++
  EEA21070.1 56 TGCLTCRKRRIKCGEEKPRCNNCIKAKRDCEGYTQR 91
                58*****************************99985 PP

>> TFIIA  Transcription factor IIA, alpha/beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6  23.1    0.0023        14     114     338 ..      95     339 ..      14     362 .. 0.44

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0023
       TFIIA 114 atfslpakleppvqipagvtlqtasgqlykvnvqasgaqqiaaqplqqvvqq.....sqgsaaqssvaalqaqsqqaqalaepqqqlekq......... 198
                 ++ + p + ++   +pa+++ +++   ++  +vq ++ qq+ + ++qq++qq      +g+a + +   l++  +                        
  EEA21070.1  95 KNAQGPFGADYDPRVPANLQAPVTHFPQLPPQVQLQQLQQLQQFQQQQQQQQqqdqsISGQALNRQQRLLAPRLPYVPP----------Tvlpnatalp 183
                 3444444555555888877777777644445554333333332222222222001221222222222222222111122..........1223334444 PP

       TFIIA 199 .qqqqqqqqqqqqqqqvqqqqqe.....................esqqaqqasqe.........qvag.sqvessqtdgaedaleeespv.legelsae 264
                  +qqqqqq+ + +    q+ +q+                     +                   ++++ +++ +s++dga +a+++++++ l  +++++
  EEA21070.1 184 iHQQQQQQPLHYHTIPLQTPSQAepiiapqsihaptgdftshvhT---------WssadqltylALPEtTNAFQSSHDGAFQAQTTAETIpLSHQHMDT 273
                 344455555555555444433334666665555555555433321.........022222233333333444455555555666555555555555444 PP

       TFIIA 265 eeagaqkeelsreeidri.reealkakelekeskkkkr.aeessladlseilqlDGagddsdeeeeeeesdedsds 338
                 ++           + d   ++ a +   +++++ ++++   +++++++  i+ +  ++d +d+     + d+d+d+
  EEA21070.1 274 NPVSIV-------QQDPAvQSMAETIGFYTDDTFQQAQvYYAWDAEQEALIPTIYAPEDLEDD---YYDVDSDDDQ 339
                 443332.......22222111122223334444444443333666666666666666666666...3333333332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1043 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1477  (0.0823805); expected 358.6 (0.02)
Passed bias filter:                      648  (0.0361426); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.86u 0.35s 00:00:01.21 Elapsed: 00:00:00.50
# Mc/sec: 6236.88
//
Query:       EEA21071.1  [L=537]
Description: rRNA processing protein Rrp8, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.8e-54  184.3   0.1    5.8e-51  173.4   0.0    2.9  3  Methyltransf_8   Hypothetical methyltransferase
    1.5e-06   28.7   0.0    4.3e-06   27.3   0.0    1.9  1  Methyltransf_11  Methyltransferase domain
    3.6e-05   24.4   0.0     0.0014   19.3   0.0    2.6  1  Methyltransf_25  Methyltransferase domain
  ------ inclusion threshold ------
       0.43   10.8   2.0          1    9.6   0.0    2.7  3  DNA_pol_B_thumb  DNA polymerase beta thumb
       0.79    8.9   8.7          4    6.6   0.1    2.3  2  Zip              ZIP Zinc transporter
       0.94    9.5   0.0       0.94    9.5   0.0    3.3  2  Methyltransf_32  Methyltransferase domain
        1.3    8.1  10.8       0.32   10.2   3.8    2.2  2  DUF4471          Domain of unknown function (DUF4471)
        3.8    7.6   9.9         19    5.3   6.5    2.4  2  DDHD             DDHD domain
        5.8    6.1  18.8      0.038   13.3   6.7    2.3  2  FmiP_Thoc5       Fms-interacting protein/Thoc5
        6.8    6.8  20.7        6.2    7.0  12.7    2.7  2  CPSF100_C        Cleavage and polyadenylation factor 2 C-term
        9.1    5.6  15.6        2.9    7.3   8.2    2.3  2  DUF4746          Domain of unknown function (DUF4746)


Domain annotation for each model (and alignments):
>> Methyltransf_8  Hypothetical methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  173.4   0.0   3.5e-54   5.8e-51       2     178 ..     171     379 ..     170     408 .. 0.86
   2 !    7.2   0.0    0.0026       4.2     165     203 ..     437     477 ..     434     488 .. 0.81
   3 ?   -1.1   0.0      0.88   1.4e+03     205     219 .]     523     537 .]     513     537 .] 0.74

  Alignments for each domain:
  == domain 1  score: 173.4 bits;  conditional E-value: 3.5e-54
                     XXXXX-HHHHHHHHHHHHHHHHHS-HHHHHHHHHH-HHHHHHHHHHHHHHHC.TSSS-HHHHHHHHHC.........................TS CS
  Methyltransf_8   2 leakikkrldgarfrflneklytgesskavdlfkedpeafdlyhkgfrsqvk.kWPenPldviirklk.........................kk 70 
                     l++k++++l ++rfr+lne lyt++s++a+ +f+ +pe+f+ yh+gf  qvk  WP nP+d  i  ++                         ++
      EEA21071.1 171 LQQKMRDKLISSRFRHLNETLYTTPSKQAQAMFEANPELFTEYHNGFSRQVKeSWPSNPVDGYIAAVRkrgvvpahhdkrkhnnsnnavaplpRR 265
                     79*************************************************836**************************************977 PP

                     -TT.S-EEEES-TT-HHH.....HH--S-..EEEEESS-SSTT.EEES-TTS-S--TT-EEEEEEES---SS-HHHHHHHHHHHEEEE..EEEEE CS
  Methyltransf_8  71 kdn.lvvadlGcGeakia.....eavrekekvrsfdlvavner.vvacdlakvPledesvdvavfclslmgtnladflkeanrvlkvG..Gllkv 156
                     ++   ++adlGcG+a+ a     +a++ + k+ s+dl++++e  v+  d+a++P+ d+svdv++fclslmgtn+ +f++ea rvl+    G  +v
      EEA21071.1 266 PNGfCTIADLGCGDAQFArsltaSAKKLQLKLTSYDLQSPDEAlVTKADIANLPVTDGSVDVTIFCLSLMGTNWVSFIEEAWRVLRGDgkGECWV 360
                     765268**********99666545566677899*******99747889**************************************7623579** PP

                     EEEGGG-S-HHHHHHHHHCTTE CS
  Methyltransf_8 157 aevksrfesvklfaraltklGf 178
                     +evksrf +v+    +  ++G+
      EEA21071.1 361 SEVKSRFGKVNR---KKAQIGL 379
                     *******88764...4444555 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0026
                     -HHHHHHHHHCTTE..EEEEEE--STTEEEEEEEE-SSS-T CS
  Methyltransf_8 165 svklfaraltklGf..evkskdlsnkqfvlfefkkvekkgk 203
                     ++  f++ +++ Gf  +++s+d snk+fv +ef k +    
      EEA21071.1 437 DISAFVEVFKSRGFvlKQESVDKSNKMFVKMEFIKAGGAPT 477
                     678899999999996678899************99875544 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 0.88
                     ---GG--------XX CS
  Methyltransf_8 205 relglklkpclykkr 219
                     ++    lkpc+yk r
      EEA21071.1 523 EQEAKVLKPCVYKIR 537
                     4556789******76 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.0   2.6e-09   4.3e-06       2      93 ..     274     355 ..     273     358 .. 0.82

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 2.6e-09
                      EET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-EEEETTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHHHHHEEEEEE CS
  Methyltransf_11   2 dvGcGtGrlaealakrgarvvgvDlskemlklakekaseeglkvefvvadaeklpfednsfDlvvssevlhhvedpekalkeiaRvLkpgGl 93 
                      d+GcG  ++a+ l+   a+ + + l+ + l+       +e l   + +ad+ +lp+ d+s+D+ +   +l+   ++ ++++e++RvL+ +G+
       EEA21071.1 274 DLGCGDAQFARSLTAS-AKKLQLKLTSYDLQSP-----DEAL---VTKADIANLPVTDGSVDVTIFCLSLMGT-NWVSFIEEAWRVLRGDGK 355
                      99************33.4666777777766333.....3332...3789***********************9.6*************9996 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.0   8.7e-07    0.0014       1      97 []     272     354 ..     272     354 .. 0.71

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 8.7e-07
                      EEEET-TTSHHHHHHHCTST..SSEEEEEESSHHHHHHHHHHHHHTTT.TEEEEESBCCGBSSSTTTEEEEEEESTGGGSSHHHHHHHHHHHHH CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlg..kakvtgvDiseemleaareraeeegl.nvefvqgdaedlpfedgsfDlvvssgalhhlsdedlekalkeiar 91 
                      + dlGcG  ++++ l +  +  + k+t  D+++              + ++ + ++d+ +lp  dgs+D+ + +  l+++   ++  +++e++r
       EEA21071.1 272 IADLGCGDAQFARSLTASAKklQLKLTSYDLQS--------------PdEALVTKADIANLPVTDGSVDVTIFC--LSLMG-TNWVSFIEEAWR 348
                      568888888888887776521333334444332..............224457899**************9995..55555.579********* PP

                      HEEEEE CS
  Methyltransf_25  92 vLkpgG 97 
                      vL+ +G
       EEA21071.1 349 VLRGDG 354
                      ***887 PP

>> DNA_pol_B_thumb  DNA polymerase beta thumb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.4       3.9   6.3e+03      46      46 ..     101     101 ..      61     138 .. 0.58
   2 ?    9.6   0.0   0.00062         1       7      33 ..     278     304 ..     276     345 .. 0.85
   3 ?   -3.4   0.2       7.1   1.2e+04      44      44 ..     404     404 ..     378     422 .. 0.48

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 3.9
                      E CS
  DNA_pol_B_thumb  46 l 46 
                       
       EEA21071.1 101 N 101
                      1 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00062
                      S-HHHHHHHHHHHHCTTEEEETTEEE. CS
  DNA_pol_B_thumb   7 GsktFnrdlRrlakkkglkLnssglrd 33 
                      G+ +F r+l   akk +lkL+s+ l +
       EEA21071.1 278 GDAQFARSLTASAKKLQLKLTSYDLQS 304
                      999*********************984 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 7.1
                      C CS
  DNA_pol_B_thumb  44 g 44 
                      g
       EEA21071.1 404 G 404
                      1 PP

>> Zip  ZIP Zinc transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   5.4     0.016        26     101     162 ..      78     134 ..      24     257 .. 0.66
   2 ?    6.6   0.1    0.0024         4      77     168 ..     328     425 ..     303     524 .. 0.66

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.016
         Zip 101 ekksshkektpkkasssssesaakksvsndkveeseekedhvaeadtdadskeelrngkqek 162
                 e+     ++ ++ ++++ ++++ k++ +n + e++e  +++ aea++ + +k++++++ +ek
  EEA21071.1  78 EG-----QTDKSGKKNKNKTKKNKEKKENRQPETDEAVQEKPAEAREGRANKKQKKARDEEK 134
                 22.....1111222222222222222222222222222222222222222222222222222 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0024
         Zip  77 lagllvllGflllllveklltmivek..............ksshkektpkkasssssesaakksvsndkveeseekedhvaeadtdadskeelrngkqe 161
                   ++l l+G   + ++e++ + + +                       + + ++ +   ++ + + ++++++++ k ++++++++++ds+ e+ n+++e
  EEA21071.1 328 TIFCLSLMGTNWVSFIEEAWRVLRGDgkgecwvsevksrfG-------KVNRKKAQIGLKRDDAAGMSNTQKKKLK-NKKKKKNGNNDSDDEDDNDHEE 418
                 56778888888888888888888777777776644432221.......2222222222222222222222222222.2233333444444444444444 PP

         Zip 162 kseseke 168
                    ++++
  EEA21071.1 419 IYAEDAQ 425
                 3333333 PP

>> Methyltransf_32  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.0   0.00058      0.94      22      61 ..     265     304 ..     250     315 .. 0.84
   2 ?   -1.3   0.4       1.2   1.9e+03      69      89 ..     390     406 ..     362     438 .. 0.49

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00058
  Methyltransf_32  22 kesgaltvvDvGaGkgYLsfvlalkekeyklkvvgidake 61 
                      + +g +t++D+G+G +  ++ l  ++k+++lk+++ d+++
       EEA21071.1 265 RPNGFCTIADLGCGDAQFARSLTASAKKLQLKLTSYDLQS 304
                      468889******************7778999999999875 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.2
  Methyltransf_32  69 kraeklgkkfnkrlsfaelsi 89 
                      + ++kl+    ++ +++++++
       EEA21071.1 390 TQKKKLK----NKKKKKNGNN 406
                      1111111....1111122221 PP

>> DUF4471  Domain of unknown function (DUF4471)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   3.8    0.0002      0.32     144     249 ..      55     193 ..      48     215 .. 0.67
   2 ?    1.9   0.6     0.067   1.1e+02     174     212 ..     388     435 ..     362     473 .. 0.45

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.0002
     DUF4471 144 gqhvktatdvserNvlellqeletreeyklkkkksersdkveeekkekkeeeeekeeeeeakdeeeek............................... 211
                  +++k+   v++ Nv e+++   ++++ k  kk++++++k++e+k+++++e++e+ +e+ a+++e +                                
  EEA21071.1  55 AKKRKRDNGVTKSNVDEMFKRHIEGQTDKSGKKNKNKTKKNKEKKENRQPETDEAVQEKPAEAREGRAnkkqkkardeekrangdasatvddiqtattt 153
                 567788899**********98777776777777777777777766633333333332222222222224455667777888999999998888888777 PP

     DUF4471 212 .eseleelekvkvkflpl.esleklkekkkyknlFdiifv 249
                   s    ++  +vk++pl +++++   ++++++l ++++ 
  EEA21071.1 154 sVSLPPPMPPSTVKLTPLqQKMRDKLISSRFRHLNETLYT 193
                 6555666777777778877777777777777777666665 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.067
     DUF4471 174 kkkksersdkveeekkekkeeeeekeeeeeakdeeeek...............e 212
                 +++++++ ++++++k+ ++++++e+++++e+      +                
  EEA21071.1 388 SNTQKKKLKNKKKKKNGNNDSDDEDDNDHEE------IyaedaqpassgggndD 435
                 2222222222222221111111111112222......13333345555555550 PP

>> DDHD  DDHD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   6.5     0.012        19      89     170 ..      45     138 ..      10     260 .. 0.58
   2 ?    3.6   0.1      0.04        66     122     158 ..     379     416 ..     319     509 .. 0.63

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.012
        DDHD  89 elkesltsigaalkqkvsglvssls.allnrslelaeeesaslaesskshe......rasesskasqeskaaesstasssaksskaee........... 169
                 +++++  + +a+++++ +g+++s    +++r  e ++++s ++++++++++      r+ e+++a qe+ a+ ++ +++++      +           
  EEA21071.1  45 QIGQGAGNESAKKRKRDNGVTKSNVdEMFKRHIEGQTDKSGKKNKNKTKKNkekkenRQPETDEAVQEKPAEAREGRANKK------Qkkardeekran 137
                 445555555555555555555554331333332222222222222222222000000222222222222222222222222......111122233333 PP

        DDHD 170 k 170
                  
  EEA21071.1 138 G 138
                 0 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.04
        DDHD 122 laeeesaslaessksherasesska.sqeskaaessta 158
                 l+++++a +++++k++ ++++++k+ ++ s+ ++++++
  EEA21071.1 379 LKRDDAAGMSNTQKKKLKNKKKKKNgNNDSDDEDDNDH 416
                 23333332222222222222111110111111111111 PP

>> FmiP_Thoc5  Fms-interacting protein/Thoc5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   6.7   2.4e-05     0.038     186     252 ..      67     133 ..      63     201 .. 0.76
   2 ?   -1.7   4.2      0.83   1.4e+03     207     250 ..     389     414 ..     361     435 .. 0.46

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 2.4e-05
  FmiP_Thoc5 186 eavdkkleveIeGdveeakafnkssnsaeekkaeaessdsdsesq.....eekekkkkkrekqkeekeeeks 252
                 + vd+ ++ +IeG+++++ + nk++++++++k+e+ + ++d+  q           ++ r ++k++k+++++
  EEA21071.1  67 SNVDEMFKRHIEGQTDKSGKKNKNKTKKNKEKKENRQPETDEAVQekpaeA-----REGRANKKQKKARDEE 133
                 556788999*************99999999999999999999998444431.....2222222222222222 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.83
  FmiP_Thoc5 207 nkssnsaeek.kaeaessdsdsesqeekekkkkkrekqkeekeee 250
                 n+++++ ++k k+++ ++dsd+e++                   +
  EEA21071.1 389 NTQKKKLKNKkKKKNGNNDSDDEDD-------------------N 414
                 1111111111122222222222222...................1 PP

>> CPSF100_C  Cleavage and polyadenylation factor 2 C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0  12.7    0.0038       6.2      23     128 ..      76     185 ..      14     192 .. 0.76
   2 ?    3.8   0.9     0.036        58      49      87 ..     382     422 ..     353     445 .. 0.48

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0038
   CPSF100_C  23 tvtgeleieeeaeeaeeeekeeeeeeeeeeeeeeeaskkqkl....aeksekeaseeeseekkeslptldvlpankasvrsaaqplfvGdlrLadLkka 117
                 +++g+ + + ++++++ ++++e++e+ + e++e  ++k  ++    a+k++k+a++ee++++ ++  t+d +++++++  s   p+    ++L+ L ++
  EEA21071.1  76 HIEGQTDKSGKKNKNKTKKNKEKKENRQPETDEAVQEKPAEAregrANKKQKKARDEEKRANGDASATVDDIQTATTTSVSLPPPMPPSTVKLTPLQQK 174
                 77888875555444444444444444444444444333333344547777777777777777778888888888888878899999999********** PP

   CPSF100_C 118 llssgikAEFr 128
                 ++++ i++ Fr
  EEA21071.1 175 MRDKLISSRFR 185
                 *9998888886 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.036
   CPSF100_C  49 eeeeeeeeeaskkqkl..aeksekeaseeeseekkeslptl 87 
                 +++++ +++++kk k+  ++k+ +++s++e+++++e++   
  EEA21071.1 382 DDAAGMSNTQKKKLKNkkKKKNGNNDSDDEDDNDHEEIYAE 422
                 22222222222222221122222233333333333333333 PP

>> DUF4746  Domain of unknown function (DUF4746)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   8.2    0.0018       2.9      76     151 ..      83     160 ..      56     198 .. 0.59
   2 ?    2.7   0.7     0.042        68     101     130 ..     389     417 ..     348     462 .. 0.52

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0018
     DUF4746  76 evsseeetlekqekekektkakeaeltade.paeeeea.eeeeeeeaveeeeeeeeeeeeeeedkeltktktvkiPpi 151
                 ++ +++++++k++kek++++++e++++++e pae++e   ++++++a +ee+ ++ ++++ ++d ++ +t  v++Pp 
  EEA21071.1  83 KSGKKNKNKTKKNKEKKENRQPETDEAVQEkPAEAREGrANKKQKKARDEEKRANGDASATVDDIQTATTTSVSLPPP 160
                 333333444444444444455555555555444444430344445555566555666777788889999999999764 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.042
     DUF4746 101 ltadepaeeeeaeeeeeeeaveeeeeeeee 130
                 +t++++ +++++++++++++ +e+ ++ +e
  EEA21071.1 389 NTQKKKLKNKKKKKNGNNDSDDED-DNDHE 417
                 111111112222222222111121.11111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (537 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2351  (0.131128); expected 358.6 (0.02)
Passed bias filter:                      691  (0.0385409); expected 358.6 (0.02)
Passed Vit filter:                       161  (0.00897987); expected 17.9 (0.001)
Passed Fwd filter:                        70  (0.00390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 1.06u 0.35s 00:00:01.41 Elapsed: 00:00:00.51
# Mc/sec: 3194.00
//
Query:       EEA21072.1  [L=245]
Description: proteasome component Pup2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.1e-56  188.5   0.2      1e-55  188.2   0.2    1.1  1  Proteasome      Proteasome subunit
    1.5e-12   46.9   0.2    3.6e-12   45.7   0.0    1.8  2  Proteasome_A_N  Proteasome subunit A N-terminal signature


Domain annotation for each model (and alignments):
>> Proteasome  Proteasome subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  188.2   0.2   1.1e-59     1e-55       1     189 [.      31     220 ..      31     221 .. 0.95

  Alignments for each domain:
  == domain 1  score: 188.2 bits;  conditional E-value: 1.1e-59
                 HHHS-EEEEEEETTEEEEEEEEEEEETTEEEESSSSTSEEEEETTEEEEEEESHHHHHHHHHHHHHHHHHHHHHHSSGTCHHHHHHHHHHHHHHHHHHC CS
  Proteasome   1 vkkGttvvGikgkdgvvlaadkratagskllskstveKifkiddhigvafaGlaaDartlvrraraeaqlyrlrygrpipverlvarvaaklqaytqrs 99 
                 +k G+t++G+++++gvvl+++kr+t  s+ll++s+veKi +id+hig+a++Gl+aDar ++++ar+e+q++ + + + ++ve +++++++++++    +
  EEA21072.1  31 IKLGSTAIGVATSEGVVLGVEKRVT--STLLETSSVEKIVEIDQHIGCAMSGLQADARSMIEHARVECQNHAFHFAESLRVESCTQAICDLALRFGEGA 127
                 589**********************..*******************************************************************99855 PP

                 ......TTTTTSEEEEEEEEETTTEEEEEEEETTSEEEEESSEEEESTTHHHHHHHHHHHHSTTBSHHHHHHHHHHHHHHHHHHBTTSCSSEEEEE CS
  Proteasome 100 ......grrpfgvslliagvdeeggpeLyqidpsGsyieekdavaiGsgseaaktalekeykedltleeavelavkalkealerdklsgknievav 189
                         rpfgv+lliag+de+g p+Ly+ +psG++++++ a aiGsgse a++ l++ey+  ltl ea++l++k+lk+++e +kl  kn+++a 
  EEA21072.1 128 dgeesvMSRPFGVALLIAGYDEDG-PQLYHAEPSGTFYRYD-AKAIGSGSEGAQAELQNEYHRSLTLAEAETLVLKTLKQVME-EKLDAKNVQLAS 220
                 55555578*************888.***************6.*****************************************.88******9985 PP

>> Proteasome_A_N  Proteasome subunit A N-terminal signature
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.7   0.0     4e-16   3.6e-12       1      23 []       8      30 ..       8      30 .. 0.98
   2 ?   -2.9   0.0      0.64   5.7e+03       1       6 [.     186     191 ..     186     192 .. 0.89

  Alignments for each domain:
  == domain 1  score: 45.7 bits;  conditional E-value: 4e-16
  Proteasome_A_N  1 YDrslttFSPdGRLfQVEYAmkA 23
                    YDr ++tFSP+GRLfQVEY ++A
      EEA21072.1  8 YDRGINTFSPEGRLFQVEYSLEA 30
                    ********************998 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.64
  Proteasome_A_N   1 YDrslt 6  
                     Y rslt
      EEA21072.1 186 YHRSLT 191
                     99***9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (245 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       695  (0.038764); expected 358.6 (0.02)
Passed bias filter:                      552  (0.0307881); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.39
# Mc/sec: 1861.60
//
Query:       EEA21073.1  [L=902]
Description: spindle pole body component (Alp4), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.8e-68  229.0   0.0    1.7e-67  228.3   0.0    1.4  1  GCP_N_terminal  Gamma tubulin complex component N-terminal
    1.3e-62  212.0   5.3    1.3e-62  212.0   5.3    1.5  2  GCP_C_terminal  Gamma tubulin complex component C-terminal


Domain annotation for each model (and alignments):
>> GCP_N_terminal  Gamma tubulin complex component N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  228.3   0.0   1.9e-71   1.7e-67       1     306 []     183     520 ..     183     520 .. 0.88

  Alignments for each domain:
  == domain 1  score: 228.3 bits;  conditional E-value: 1.9e-71
  GCP_N_terminal   1 lrdllylLqGisgklirfdekdd......ervvkdvrl.pgllppslrslverllelgtlyrrlrkfveevsrsesglvlqalaaaldeelteyy 88 
                     l+d+l++++G++g++ir+ ++ d        v +++++ pgl +psl++l  ++l+++t+y+ l++f++  sr+e+g v +al+aa++++l++y+
      EEA21073.1 183 LQDILFVFMGYEGQYIRYHSSYDpsvekdRLVGPSFQIgPGL-DPSLKDLTISMLKMATHYSALEAFINVLSRPEYGAVSHALCAAIRKLLKDYL 276
                     79***************9776664444445566666668888.*************************999************************ PP

  GCP_N_terminal  89 rliaqlEsqlledsesiltLlrlevwlqetllllrvLanlveeve........................................kanlkggall 143
                      liaqlE+qll++++  +tL+ l++++ +t + l+ L++l +e                                          k+ +kgg++l
      EEA21073.1 277 ILIAQLENQLLNNPN--FTLHVLHLQTLPTSQSLSQLHSLSQELLrrnklldqdldesiddfddvdnileqlkeggdlvpgslssKKICKGGNVL 369
                     **************9..*************************99977777777777777777777777777777777777766655555****** PP

  GCP_N_terminal 144 sllhe..aaqhgdpkvrkllsellervsrpflemlekWileGelsDpynEfFveenesvakeklkeddseklweekYtlrkemlPsflseelaek 236
                      ll e  a+ +gdp++++ll++ll+++srp++ ml+ W+ +Ge+ Dp++Ef+++e++ +++ekl+ed+ +++we++Yt+r + +P  l++ + +k
      EEA21073.1 370 GLLTErlATFSGDPATKTLLQTLLREASRPYMIMLNEWLHHGEIRDPHGEFLIKEQKWIKREKLEEDYTDEYWEKRYTIRDNEVPPQLES-VRDK 463
                     ******9999********************************************************************************.**** PP

  GCP_N_terminal 237 IletGkslnflrescgdsewiekteseekeleyiddleelssslslsleelidsayklaskrllelLfke 306
                     +l++Gk+ln++re++g  + ++ ++      +    +   +++ + ++ + ++say +a+++ll+lL+ e
      EEA21073.1 464 VLLAGKYLNVVRECGG-VD-VN-KAV-----KD---VP--KTFDDPRFLDNVNSAYAYANTSLLNLLLSE 520
                     *************744.45.55.333.....11...22..2233457********************987 PP

>> GCP_C_terminal  Gamma tubulin complex component C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.3   0.7       1.1   9.8e+03      13      54 ..     286     322 ..     278     347 .. 0.48
   2 !  212.0   5.3   1.5e-66   1.3e-62       1     303 [.     523     893 ..     523     895 .. 0.86

  Alignments for each domain:
  == domain 1  score: -4.3 bits;  conditional E-value: 1.1
  GCP_C_terminal  13 LlgqgdFisrLldalfdelwkpasselrlaLtslLeeairss 54 
                     Ll++ +F  + l++   + +++ s+     L sl +e +r++
      EEA21073.1 286 LLNNPNFTLHVLHLQTLPTSQSLSQ-----LHSLSQELLRRN 322
                     5555555555554444444433333.....444445555543 PP

  == domain 2  score: 212.0 bits;  conditional E-value: 1.5e-66
  GCP_C_terminal   1 LlehLkllkrylLlgqgdFisrLldalfdelwkpasselrlaLtslLeeairssna.qqsdelkddlsfaldlpevleeldakldpds....... 87 
                     L  ++++lk+y++l+++dF+s ++++ ++el kpa++  + +L+slL++++r+  + ++sd++k+d+++++++  +++ l + +++++       
      EEA21073.1 523 LTTRFRSLKHYFFLDRSDFFSYFMELSASELRKPAKAVNESKLQSLLDLVLRQPGSiAASDPFKEDVKVKMNKIGLTRWLMQVVSVSGidqdnpd 617
                     6789*********************************99999**********98776669***********8888778887666776688999** PP

  GCP_C_terminal  88 ...................legldfltLeYkvpwplslvitpealekYqriFrfLlrvkrvefalsslw........krrkatgarsvl...... 149
                                        + g+d+l L+Y vp plslvi+++++ +Yq iFr+Ll ++++e+ l ++w               +++        
      EEA21073.1 618 gglekyqtpttqlaedekdIIGFDALELDYLVPFPLSLVISRKTVLRYQLIFRYLLSLRHLENLLVTSWqdqqktlgW------RHK-Ssdrrle 705
                     ***************998777*********************************************99*753333321......221.1244555 PP

  GCP_C_terminal 150 .lkra.rllrqemlhfvsqlqyYvldeviessWreleekl.kke.....................atdldelieaHeafLdsilkkclLrskkkl 220
                      +kr  ++lr++ml f++ql y+++ evie++W+ l+e++  ++                     + ++del++ H +fLd++lk+c+L++  kl
      EEA21073.1 706 mWKRRaWTLRAKMLVFIQQLLYFCTAEVIEPNWQSLMERVnGTAsgtqssallptdevdgskqvnR-TVDELMQDHVDFLDTCLKECMLTQA-KL 798
                     655555**********************************65558999888888888888877755.5*********************999.** PP

  GCP_C_terminal 221 lklleeilelileFakvldgly.lsvselt.............aeeaeeeeleekleerleelekeFrkkvslllkvlralkeqeededlrqLll 301
                     lk+ +++++++  Fa+++      s+s+++             a+  ++++l++ le++l+++e+ F++++++ll+ l+ ++++e ++ l +L++
      EEA21073.1 799 LKIHSKLMTCCTMFASWTAASLaRSMSTADpdlsagasgapadARPYDATRLAK-LEDTLKRYEDHFNRHLRILLDSLNYFAATE-SVVLLKLAH 891
                     ****************8777444555554499********99866666677777.***********************8886666.777777766 PP

  GCP_C_terminal 302 rL 303
                      L
      EEA21073.1 892 SL 893
                     65 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (902 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       627  (0.0349713); expected 358.6 (0.02)
Passed bias filter:                      396  (0.0220871); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.71u 0.27s 00:00:00.98 Elapsed: 00:00:00.44
# Mc/sec: 6119.50
//
Query:       EEA21074.1  [L=654]
Description: bifunctional fatty acid transporter/acyl-CoA synthetase (FAT1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.4e-57  195.2   0.0      2e-57  194.7   0.0    1.1  1  AMP-binding    AMP-binding enzyme
    0.00061   20.7   0.1     0.0024   18.8   0.1    2.1  2  AMP-binding_C  AMP-binding enzyme C-terminal domain


Domain annotation for each model (and alignments):
>> AMP-binding  AMP-binding enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  194.7   0.0   2.2e-61     2e-57       5     420 ..      76     506 ..      72     509 .. 0.77

  Alignments for each domain:
  == domain 1  score: 194.7 bits;  conditional E-value: 2.2e-61
                  HHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEEE... CS
  AMP-binding   5 aaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakvli... 99 
                  ++k+  + al +  e++t+TY +l++ ++rlAa++ + G++ gd Va++  nspe+v++++a+ k+G+v++ +n++l+ ++ +++le s++k++i   
   EEA21074.1  76 VNKQGSAEALWF--ENKTWTYDQLKDYSDRLAAYIHAQGIQAGDFVAVYTTNSPEMVFIVYALSKLGVVAALINTNLRDATFKHCLEISRSKLIIstp 171
                  67889999**88..**********************99*********************************************************555 PP

                  ...E..TCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS......-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHH CS
  AMP-binding 100 ...a..tvdselleklleaaakleavklvivldadellkeeelkeeeeseekae......kpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlva 186
                     a  ++d+  ++k   + ++  +  + i +d  ++  e+ +          +          +++ +p dla++iYTSGTTG+PK++ ++   ++ 
   EEA21074.1 172 dlaAfvKTDD--MPKFTFNVSS-FDNVTDIPSDITQITPETLS----------QfsaadiAAIAAAKRSPPDLAVLIYTSGTTGNPKACAIRNSMTLV 256
                  4431221111..2222222221.11112222333333333222..........1333444233566899*********************98854444 PP

                  HHHHHHHHHC.SCCTT....T-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHH CS
  AMP-binding 187 nvaslkletr.fklke....ddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakka 279
                  + + l  +++ ++  +      +++s lpl+h +++ ++l++++ +G+t++l +k++a  ++ +++++++ ++t + ++ +++++ll+s++       
   EEA21074.1 257 TSTPL--PKDtRN--PskyyPMRIYSSLPLFHGTAFFSGLCYSVGNGGTLCLRRKFSA--SQ-FWKDVHDSRATRVLYIGELCRYLLASPPSP----- 342
                  43333..333222..22344679*********************************99..44.56***********************87555..... PP

                  CCGTT.-SEEEEESS-EBHHHHHHHHHHHTC.EEEEEEEEGGGSSEC.EECHCTTTCTSTTS-B.....EE-TTEEEEEE..-TTTSCBEE....... CS
  AMP-binding 280 kdlss.lrlvllggeplspellrffralfge.evlegYGlTEttgvv.tvlpleedkkklgsvG.....kplpgvevkiv..Deetgepvp....... 360
                    + + +  v++ g+ l+ e++++f+++f   e+ e+Y  TE  + +  +   ++    +g vG     + + +++ +++  D et++p +       
   EEA21074.1 343 --FDKnHNCVVAYGNGLRGEIWDKFSERFNVaEIREIYRSTEGVARFdNFSGGSWG---AGAVGfhgpiRQMFEQDTYLIkfDLETEQPYRdpktgfc 435
                  ..4454788889*****************9999************99732333333...455555545544555555544457777777767788888 PP

                  ....TTSEEEEE..EEETTS-SEBTT-HHHHHHHEEE...T.CC.EEEEEEEEEEETTSEEEEEEECCCEE CS
  AMP-binding 361 ....dgeeGell..vrgpgvmkgYlkkpeataeafds...e.gr.wlrTGDlgrldedGyleivgRkkdli 420
                       geeGe    vr  +    Yl + eat++++ +   e g+ + r GDl ++d+dG +++ +R  d+ 
   EEA21074.1 436 vkvsAGEEGEAIgrVRTRQSLTEYLHNNEATEKKLLTdvfEkGDvFQRMGDLLVRDHDGWIRFGDRVGDTY 506
                  8899******88789*******************9978995588899*******************99985 PP

>> AMP-binding_C  AMP-binding enzyme C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0         2   1.8e+04      42      59 ..     206     223 ..     195     226 .. 0.73
   2 !   18.8   0.1   2.7e-07    0.0024       2      69 ..     518     591 ..     517     598 .. 0.80

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 2
                    HHHHHHHHHHHHT-TTTS CS
  AMP-binding_C  42 leeeLkahvrkelgpyav 59 
                    ++e+L ++ ++ ++++a+
     EEA21074.1 206 TPETLSQFSAADIAAIAA 223
                    678999999999999875 PP

  == domain 2  score: 18.8 bits;  conditional E-value: 2.7e-07
                    HHHHHHSSTTEEEEEEE-----.TTS---EEEEEE---..---...HHHHHHHHHHH.HT-TTTS-SEEEE-S-- CS
  AMP-binding_C   2 vEsalvshpaVaeaaVvGvpde.vkGealvafVvlkdg..sea...leeeLkahvrk.elgpyavpkkvvfvdel 69 
                    v   + ++++V++a+V+Gv+ +  +G+a +a ++l++   +       e+L  ++r+  +++ya p+ v++++e+
     EEA21074.1 518 VRDHICRMENVQDAVVYGVKLKnYDGQAGAAGITLERRtpE-TeaaAIENLWTFLRSqGVPTYAIPRLVRVTKEV 591
                    556688999*************99***********644331.12457888888886658999********99886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (654 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       532  (0.0296726); expected 358.6 (0.02)
Passed bias filter:                      499  (0.027832); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.68u 0.31s 00:00:00.99 Elapsed: 00:00:00.51
# Mc/sec: 3829.64
//
Query:       EEA21075.1  [L=421]
Description: peroxisomal 3-ketoacyl-coA thiolase (Kat1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.4e-64  216.1   1.6    6.1e-64  215.9   0.1    1.9  3  Thiolase_N     Thiolase, N-terminal domain
    5.3e-43  145.6   0.6    5.3e-43  145.6   0.6    1.7  2  Thiolase_C     Thiolase, C-terminal domain
     0.0036   17.1   0.2       0.22   11.4   0.1    2.5  2  ACP_syn_III    3-Oxoacyl-[acyl-carrier-protein (ACP)] synthas
  ------ inclusion threshold ------
      0.043   14.0   0.0       0.12   12.6   0.0    1.8  1  ACP_syn_III_C  3-Oxoacyl-[acyl-carrier-protein (ACP)] synthas
      0.057   13.0   2.0       0.13   11.8   1.0    2.1  3  ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
       0.15   12.1   0.6       0.42   10.7   0.6    1.8  1  SasG_E         E domain


Domain annotation for each model (and alignments):
>> Thiolase_N  Thiolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0         2   5.8e+03     108     120 ..      15      27 ..       9      31 .. 0.80
   2 !  215.9   0.1     2e-67   6.1e-64       1     260 []      35     290 ..      35     290 .. 0.93
   3 ?   -3.3   0.1       1.6   4.7e+03      59      92 ..     379     413 ..     362     416 .. 0.76

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 2
                 EEEEEEESTTS-E CS
  Thiolase_N 108 vagGvEsmsnapt 120
                 + gG+Es+s++  
  EEA21075.1  15 ITGGGESLSRKRV 27 
                 789*****99865 PP

  == domain 2  score: 215.9 bits;  conditional E-value: 2e-67
                 EEEEEEEEE--EE.TTSTTTTS-HHHHHHHHHHHHHHHHTS-GGGCCEEEEEHSSCTTSTSCHHHHHHHHTTS-TTSEEEEEEHGGGHHHHHHHHHHHH CS
  Thiolase_N   1 vvivsaartpigk.fggslkdlsaeeLlaealkallekagvdpeevdevivGnvlqagegqniarqaalkagipeevpavtvnkvcsSglkavalaaqs 98 
                 +vi  a+rtp++k ++g lkd++ ++Ll ++l+ + ek ++dp+ v++v vGnvl+  ++  +ar a+l+ag+pe+++a+   ++csSgl a+ ++a++
  EEA21075.1  35 IVITLAVRTPLTKaKKGGLKDTPLDDLLISLLTTVREKSNLDPNLVEDVCVGNVLNPSAT-YLARSAVLAAGFPETTAASIASRFCSSGLLAIQQIANQ 132
                 69999********9******************************************9875.59************************************ PP

                 HHTTSHSEEEEEEEEESTTS-EEETCTTTTGGSSSSEEEEEHHHHHHTEETTTTSEHHHHHHHHHHHHT--HHHHHHHHHHHHHHHHHHHHTTTTTTTB CS
  Thiolase_N  99 iaageadvvvagGvEsmsnaptaestdvrsglklgdekakdllipdgladafneehmGltaenlakkykisReeqdefAvkshqkaaaaqkagkFkdei 197
                 i ag+++v +a+G+Esms++p   +    s   l ++ a++ l             mG t+en+a ++++sR + defA+ s qka++aqkag Fkdei
  EEA21075.1 133 IIAGAIEVGIAIGAESMSTNPDGGA-PPFSDRILSHSLASQNLQ-----------PMGQTSENVAGQFGLSRAQMDEFAALSFQKAEKAQKAGWFKDEI 219
                 **********************998.455555555555555554...........56****************************************** PP

                 E-EEEEESSSEE......EE-S-TTS-TT--HHHHHTS-BSSSTT..SS-BTTSB--BEEEEEEEEEEEHH CS
  Thiolase_N 198 vPvkvkgkkgkk......tvdkdeairsevtaekLaklkpaFkke..GtvtAgnasqisDGaaavllmses 260
                 +P+k+++k+ k+      +vd+d++ir ++tae+L k++ aF +     +t gnasqi+DGaaa++lm++s
  EEA21075.1 220 IPIKTTVKDPKTgevkevIVDSDDGIRYGTTAESLGKIRAAFPQWepSNTTGGNASQITDGAAALILMKRS 290
                 ********9996689999************************8754799*******************985 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 1.6
                 TSCHHHHHHH.HTTS-TTSEEEEEEHGGGHHHHHH CS
  Thiolase_N  59 gqniarqaal.kagipeevpavtvnkvcsSglkav 92 
                 g++ arq++   a++ ++   ++v+ +c    +a+
  EEA21075.1 379 GATGARQVVTaLAELRRSNKRIAVTSMCVGTGMAM 413
                 66667776541578888888888888888777776 PP

>> Thiolase_C  Thiolase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       2.5   7.3e+03      71      84 ..     133     146 ..     123     150 .. 0.77
   2 !  145.6   0.6   1.8e-46   5.3e-43       4     121 ..     300     417 ..     297     419 .. 0.97

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 2.5
                 TT--HHHH-B-TTT CS
  Thiolase_C  71 vnGGaialGHPlGa 84 
                 +  Gai +G  +Ga
  EEA21075.1 133 IIAGAIEVGIAIGA 146
                 56799999988887 PP

  == domain 2  score: 145.6 bits;  conditional E-value: 1.8e-46
                 SEEEEEEEEEE--GGGGGGHHHHHHHHHHHHHT--GGGESEEEE--SBHHHHHHHHHHHT--GGGBSTT--HHHH-B-TTTHHHHHHHHHHHHHHHCTT CS
  Thiolase_C   4 lakirsyaevgvdpeilglgPayaikkvlkkagltvedidlfEinEAFaaqaLavakaldldlekvNvnGGaialGHPlGasGaRivvtllselkkegg 102
                 ++k+++ +++g +p+i+g+gP+ ai+k+l+k+gl+ved+d+fEinEAFa+  ++++++l+l l+kvN +GGaia GHPlGa+GaR+vvt+l el+++++
  EEA21075.1 300 IGKFVAATVAGLEPRIMGIGPTVAIPKILSKTGLNVEDVDVFEINEAFASMGVYCVQNLNLPLSKVNPRGGAIAFGHPLGATGARQVVTALAELRRSNK 398
                 67889999******************************************************************************************* PP

                 SEEEEEEEETTTEEEEEEE CS
  Thiolase_C 103 klgvaalCigggqgvalvi 121
                 +++v+++C g+g+++a v+
  EEA21075.1 399 RIAVTSMCVGTGMAMAGVF 417
                 ***************9876 PP

>> ACP_syn_III  3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.4   0.1   7.4e-05      0.22       5      39 ..     117     151 ..     115     158 .. 0.93
   2 ?    3.0   0.0     0.031        92      52      65 ..     277     291 ..     265     305 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 7.4e-05
                  -GGGHHHHHHHHHHHHHHTTS-SEEEEEEEEEGGG CS
  ACP_syn_III   5 aaCsgfvyalsvAdaliesgaakrvLvigaetlsk 39 
                    Cs+ + a+++ ++ i +ga++  + igae +s 
   EEA21075.1 117 RFCSSGLLAIQQIANQIIAGAIEVGIAIGAESMST 151
                  57*******************************97 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.031
                  B-EEEEEEEEEEE.S CS
  ACP_syn_III  52 fGDGAgAvvleas.e 65 
                    DGA+A++l +  +
   EEA21075.1 277 ITDGAAALILMKRsH 291
                  67********98742 PP

>> ACP_syn_III_C  3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   3.9e-05      0.12       1      87 [.     328     417 ..     328     419 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 3.9e-05
                    HHHTT--GGG-SEEEE-SSSHHHHHHHHHHHT--GGGB.....--TH.HHH-B-GGGHHHHHHHHHHHTTSS-TT-EEEEEEEETTTEEEEEE CS
  ACP_syn_III_C   1 Lekagltpedidalvphqanlriidavakklglpeekv.....vvnl.deyGntsaasiplaLdeaveegklkpgdlvllvgfGaGltwgaal 87 
                    L+k+gl++ed+d++ ++ a +++    +++l+lp  kv     ++ + + +G t+a  ++ aL+e+ +++   +   v  + +G G+ ++++ 
     EEA21075.1 328 LSKTGLNVEDVDVFEINEAFASMGVYCVQNLNLPLSKVnprggAIAFgHPLGATGARQVVTALAELRRSN---KRIAVTSMCVGTGMAMAGVF 417
                    6899***************************9998876444445566699*****************944...44444555588888888776 PP

>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   1.0   4.5e-05      0.13     175     207 ..     119     151 ..     109     157 .. 0.91
   2 ?   -3.2   0.0       1.6   4.9e+03      78      99 ..     191     209 ..     180     219 .. 0.75
   3 ?   -2.3   0.0       0.9   2.7e+03     235     253 .]     274     292 ..     256     292 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 4.5e-05
                    GGHHHHHHHHHHHHHHTTS-SEEEEEEEE---S CS
  ketoacyl-synt 175 CsSslvavhaavqslrsgeadvalaGGvelllt 207
                    CsS+l a++++ +++ +g ++v +a G+e + t
     EEA21075.1 119 CSSGLLAIQQIANQIIAGAIEVGIAIGAESMST 151
                    ****************************99876 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 1.6
                    HHHHHCTS-HHHHHHHHHHHHH CS
  ketoacyl-synt  78 spreaeamdpqqrllleaawea 99 
                    s     +md ++ l+ + a++a
     EEA21075.1 191 SRA---QMDEFAALSFQKAEKA 209
                    444...8999999999998887 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 0.9
                    SB-BB-EEEEEEEEECHHH CS
  ketoacyl-synt 235 GfvlGEGvGavvLkrleda 253
                       +++G++a++L+++++a
     EEA21075.1 274 ASQITDGAAALILMKRSHA 292
                    5567899999999998876 PP

>> SasG_E  E domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.6   0.00014      0.42      20      48 .]     218     248 ..     211     248 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00014
                 EEE--B-EEEETTTTEEEE--B-..EEEEE- CS
      SasG_E  20 eevPGKPGvKnPdtGevvtpPvD..dvtKyG 48 
                 e +P K  vK P tGev +  vD  d ++yG
  EEA21075.1 218 EIIPIKTTVKDPKTGEVKEVIVDsdDGIRYG 248
                 66899************88877522667776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (421 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       535  (0.0298399); expected 358.6 (0.02)
Passed bias filter:                      451  (0.0251548); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.56u 0.30s 00:00:00.86 Elapsed: 00:00:00.48
# Mc/sec: 2660.05
//
Query:       EEA21076.1  [L=596]
Description: WSC domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-86  290.6   0.3    1.6e-86  290.1   0.3    1.2  1  DUF1996   Domain of unknown function (DUF1996)
      1e-20   73.7   8.9    3.8e-20   71.9   8.9    2.1  1  WSC       WSC domain


Domain annotation for each model (and alignments):
>> DUF1996  Domain of unknown function (DUF1996)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  290.1   0.3   1.8e-90   1.6e-86       1     233 []      39     276 ..      39     276 .. 0.93

  Alignments for each domain:
  == domain 1  score: 290.1 bits;  conditional E-value: 1.8e-90
     DUF1996   1 DPivspgevsshvHtivGgsafnasltyeelrkskctscevkeDkSnYWvptLYfkkengsferve.......qkggllvYYllekkk.ekkvtafpkg 91 
                 DPivspg++s hvH+i Ggs+f++++ty+++r+s+c+sc +k+D SnYWvp+LY++++ng++ +v+       + gg++vYYl+++ + ++ ++afp+g
  EEA21076.1  39 DPIVSPGAMSGHVHSIAGGSGFGFNMTYQDARASSCSSCPIKADLSNYWVPHLYYRAQNGTYVQVPisgdgrgNLGGITVYYLQRPGAnKDPLKAFPEG 137
                 9**********************************************************************99999********887767778****** PP

     DUF1996  92 frmiaGdptlr..ekslaqkaisftcleseekeeaeeetkelpkktkkkcasglraeilfpsCwdgknldspdhkshvaypskveesegkCpeshpvrl 188
                 frm+aGdp +r  + + a + +s+ cl++++ +  ++et+++p   + +ca+glra+++fpsCwdgknldspdhksh++yp ++  ++g Cp++hpv+l
  EEA21076.1 138 FRMLAGDPFRRnfTGDFAAQGVSYACLDYNGPA--RPETNGFP---NYNCADGLRAQVFFPSCWDGKNLDSPDHKSHMSYPISGAYNDGVCPDTHPVHL 231
                 ***********4444455678********9644..689*****...678********************************888889************ PP

     DUF1996 189 pqlfyeviwdtekfnkk.edgksqpfvlsngdktGyglHaDFinGW 233
                 +++fyevi++t+ f+++  d+ +qpfv+++gd+tGyg+H+DF+nGW
  EEA21076.1 232 VSIFYEVIFQTNLFADQwWDN-KQPFVWAMGDPTGYGFHGDFVNGW 276
                 ***************995444.89********************** PP

>> WSC  WSC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.9   8.9   4.2e-24   3.8e-20       1      82 []     379     461 ..     379     461 .. 0.95

  Alignments for each domain:
  == domain 1  score: 71.9 bits;  conditional E-value: 4.2e-24
         WSC   1 ylGCytdssesrrllgpssasdstmtpekCaafCkakgykyagledgseCyCgnslpaaavkassss..CnasCsGdssqtCGg 82 
                 y+GC  d   s+r+l++s++s+ +mt+e+C++fC+++gy+yagle++++CyCgns+++a+++ +     C  +C G+s+q+CGg
  EEA21076.1 379 YVGCAFDD-VSSRTLDGSNESQGDMTVEQCISFCSKAGYSYAGLEYSTQCYCGNSIAPAKAPIAGVVggCLFPCGGNSTQMCGG 461
                 99**9988.6999*********************************************99998776689**************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (596 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       578  (0.0322383); expected 358.6 (0.02)
Passed bias filter:                      260  (0.0145016); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.42
# Mc/sec: 4220.24
//
Query:       EEA21077.1  [L=332]
Description: glutathione S-transferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.9e-08   33.5   0.0    4.1e-07   30.3   0.0    2.3  2  GST_N     Glutathione S-transferase, N-terminal domain
      8e-08   32.4   0.0    1.5e-07   31.5   0.0    1.5  1  GST_C_3   Glutathione S-transferase, C-terminal domain
    1.4e-06   28.5   0.0    2.2e-06   27.8   0.0    1.4  1  GST_C     Glutathione S-transferase, C-terminal domain
    2.2e-06   27.6   0.1      5e-06   26.4   0.1    1.6  1  GST_C_2   Glutathione S-transferase, C-terminal domain
    1.7e-05   25.1   0.2     0.0003   21.1   0.1    2.5  2  GST_N_3   Glutathione S-transferase, N-terminal domain
     0.0026   18.0   0.3      0.032   14.5   0.0    2.8  2  GST_N_2   Glutathione S-transferase, N-terminal domain


Domain annotation for each model (and alignments):
>> GST_N  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.3   0.0   1.4e-10   4.1e-07       7      65 ..      89     150 ..      86     151 .. 0.90
   2 ?    0.3   0.0      0.29   8.8e+02      58      72 ..     157     178 ..     152     182 .. 0.71

  Alignments for each domain:
  == domain 1  score: 30.3 bits;  conditional E-value: 1.4e-10
                 SSSTSHTHHHHHHHHH....HTT-EEEEEEECSTTTCGGCHHHHHHCTTS-SSEEEETTEEEE CS
       GST_N   7 sirgsprahrirllla....akgveyevvpldfeageekspellklnplgkvPaLedngkklt 65 
                 ++++s+ + r++++l+     +g+ey+ +++++ +g+ ++++l+ ++plgk+P+Le++g  l+
  EEA21077.1  89 HHLSSSSSLRVLWALEelflSSGLEYNLKNYKRVKGR-APEDLKTVFPLGKSPVLEIPGVNLF 150
                 7888999*********877778**********98885.68*****************998886 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.29
                 EET.......TEEEESHHHHHH CS
       GST_N  58 edn.......gkkltESraIle 72 
                  d+       + + tESr Il+
  EEA21077.1 157 HDDssnnneiKTIMTESRLILQ 178
                 55555556667889******98 PP

>> GST_C_3  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.5   0.0   5.1e-11   1.5e-07      22      96 ..     244     319 ..     230     322 .. 0.83

  Alignments for each domain:
  == domain 1  score: 31.5 bits;  conditional E-value: 5.1e-11
                 HHHHHHHHHCHHHHHHHHHHCHGTSSSSTTS--HHHHHHHHHHHHHHHH..TCCCC-HHHHHHHHHHHTSHHHHHHH CS
     GST_C_3  22 kefleerlpkflkyfekvlkkkgggylvgdklTyADlalfqvldgleea..ealkkfpklkalyervearpkikaYl 96 
                 +++l++ l  +++ +e++l+ ++++++ g+k+ +AD++l   +d+  +     +kk+pkl+ +++rv+ rp+ ++ l
  EEA21077.1 244 AKILKQGLDPHFDLMERALS-DEKPWFSGSKIGLADFTLTFPMDTAVQRqfLDEKKYPKLAGWVKRVHDRPAYQNAL 319
                 5778899999**********.8999************98776666655545444*****************866665 PP

>> GST_C  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0   7.3e-10   2.2e-06       3      93 .]     225     313 ..     223     313 .. 0.80

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 7.3e-10
                 HHHHHHHHHHHSTTHHHHHHHHHHHHHHHHHHHHHHHHHHH.TSSSSSTTSSCHHHHHHHHHHHHHHHHTTTTTTTTSHHHHHHHHHHHTSH CS
       GST_C   3 dlisqilllfyvkaeekkeelvdealekvaevlsaleeelk.kqdylvGdkltlADialvpilnwlqrlglafgqekfpnlkawlerimarp 93 
                 +++s++l+ ++++a+ ++   ++++++ ++  ++  e  l+  + ++ G+k++lAD+ l++  + + ++++   ++k+p+l  w++r+  rp
  EEA21077.1 225 PTMSPWLVRPLMSAIFNP--IAKILKQGLDPHFDLMERALSdEKPWFSGSKIGLADFTLTFPMDTAVQRQFLD-EKKYPKLAGWVKRVHDRP 313
                 667777777777776444..48888999999999*******9999************9999999555444433.37************9988 PP

>> GST_C_2  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.4   0.1   1.7e-09     5e-06       5      69 .]     245     308 ..     241     308 .. 0.90

  Alignments for each domain:
  == domain 1  score: 26.4 bits;  conditional E-value: 1.7e-09
                 CHHHHHCCHCHHHCTTT---SS..CTTCS--HHHHHHHHHHHHHHHHHHS----TT-HHHHHHHHH CS
     GST_C_2   5 eraleqldaaldaleahLadsp.flfGdqptlaDialapflvrlraagpgfdireaypnlraWler 69 
                 +++++ ld ++d++e+ L d   ++ G++++laD++l+     + ++   f  +++yp+l+ W++r
  EEA21077.1 245 KILKQGLDPHFDLMERALSDEKpWFSGSKIGLADFTLTFPMDTAVQRQ--FLDEKKYPKLAGWVKR 308
                 668999**************999**************98877777776..6788**********98 PP

>> GST_N_3  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.1   0.1     1e-07    0.0003       7      73 ..      93     186 ..      88     192 .. 0.82
   2 ?   -3.6   0.0       5.1   1.5e+04      16      39 ..     293     316 ..     290     322 .. 0.64

  Alignments for each domain:
  == domain 1  score: 21.1 bits;  conditional E-value: 1e-07
                 SHHHHHHHHHHHHHT--....EEEE---..TTTTHHHHHHH-TT--SSEEETTS-.....................EEESHHHHHHHHHHHH-G CS
     GST_N_3   7 SpyarrvrlaLnekglp....vevvevt..pgehdeellaknplgkvPvLeddge.....................altdSlaIidyLeelypg 73 
                 S  + rv +aL+e+ l+    +++ +    +g+ +e l+ + plgk PvLe++g                      ++t+S+ I++ L ++y++
  EEA21077.1  93 SSSSLRVLWALEELFLSsgleYNLKNYKrvKGRAPEDLKTVFPLGKSPVLEIPGVnlfrplpflhddssnnneiktIMTESRLILQLLSDKYSN 186
                 44578999****998866655666665444788899999999********98877788889999999999999******************984 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 5.1
                 HHHHHT--EEEE---TTTTHHHHH CS
     GST_N_3  16 aLnekglpvevvevtpgehdeell 39 
                 +L+ek++p    +v   + +++++
  EEA21077.1 293 FLDEKKYPKLAGWVKRVHDRPAYQ 316
                 677888776666666666666665 PP

>> GST_N_2  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0      0.58   1.7e+03      26      50 ..      24      48 ..       9      59 .. 0.73
   2 !   14.5   0.0   1.1e-05     0.032       5      67 ..      96     180 ..      92     183 .. 0.69

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.58
                ...-TTSHHHHHHHHCTTTSSSEEE CS
     GST_N_2 26 lepkgfekseefprlnprgtVPvLw 50
                +   +++ + ++   +++++VP  w
  EEA21077.1 24 HVASDEDEGNWVGSGHHKFSVPFRW 48
                4456777888999999999999755 PP

  == domain 2  score: 14.5 bits;  conditional E-value: 1.1e-05
                 HHHHHHHHHHC....T--EEEEEEH...-TTSHHHHHHHHCTTTSSSEEE-.............CTTE.......EEESHHHHHHHH CS
     GST_N_2   5 ahRvlialalk....glediisvvvlepkgfekseefprlnprgtVPvLwd.............kdgq.......vineSseIlryl 67 
                 + Rvl+al+++    gle+ ++ +   +   +++e+++ + p+g+ PvL +             +d++       + +eS+ Il+ l
  EEA21077.1  96 SLRVLWALEELflssGLEYNLKNY--KRVKGRAPEDLKTVFPLGKSPVLEIpgvnlfrplpflhDDSSnnneiktIMTESRLILQLL 180
                 789******986666788888888..334445679*********9999999777777777777623332334443555777776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (332 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       390  (0.0217525); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2239.69
//
Query:       EEA21078.1  [L=810]
Description: alfa-L-rhamnosidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   5.1e-129  430.4   0.1   6.7e-129  430.0   0.1    1.2  1  Bac_rhamnosid6H  Bacterial alpha-L-rhamnosidase 6 hairpin gly
      7e-55  185.5   0.0    1.5e-54  184.4   0.0    1.6  1  Bac_rhamnosid_N  Alpha-L-rhamnosidase N-terminal domain
    6.7e-26   90.2   0.0    1.2e-25   89.4   0.0    1.4  1  Bac_rhamnosid    Bacterial alpha-L-rhamnosidase concanavalin-
     0.0054   16.4   0.0       0.77    9.3   0.0    2.2  2  DUF3344          Protein of unknown function (DUF3344)


Domain annotation for each model (and alignments):
>> Bac_rhamnosid6H  Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  430.0   0.1  1.5e-132  6.7e-129       2     340 .]     447     799 ..     446     799 .. 0.98

  Alignments for each domain:
  == domain 1  score: 430.0 bits;  conditional E-value: 1.5e-132
                      B-EEEEES-HHHHHHHHHHHHHHHHTBSSSB-S-SSSS----BHHHHHHHHHHHHHHB--HHHHHHHHHHHHHH--T.TS..--BSBSS--T.. CS
  Bac_rhamnosid6H   2 qtgsfecsdpllnrlhenvlwsvrsnflgvptDCPqrdErlgWtgdaqlfaptasylydveaflekwlrdladeqre.ng..avptvaPevl.. 90 
                      + g+f+cs+p++n+lh n++ws+r+nfl++ptDCPqrdErlgWtgd+q+f+p+a++ly+++++l +wl+d+a eq + ng  ++p+v+P+v+  
       EEA21078.1 447 RSGWFSCSHPMVNQLHANAWWSMRGNFLSIPTDCPQRDERLGWTGDIQIFCPSANFLYNTAGILGDWLQDVAAEQLKeNGgcVPPFVVPNVIse 540
                      579************************************************************************8867788899********* PP

                      ..T--B--TTTTTHHHHHHHHHHHHH--HHHHHHHHHHHHHHHHHHHHTSBT.TB.--S-S--STT........-SS----HHHHHHHHHHHHH CS
  Bac_rhamnosid6H  91 ..galsetaeWadaivivpwelyetygDkeilkkqYesmkryldylkqrsddgleelskfqlgDWldpe...ardgaaktekalvataylvrsl 179
                        ++ +++a W+d++++ pw+ly  ygD+eil++q esm +++d++ +r  dgl++   +qlgDWldp     ++g+a+t+++lva+aylv+++
       EEA21078.1 541 klWPHTPQAVWDDVVILTPWALYLSYGDREILRRQHESMLAWIDRGIRRGSDGLWDPDLWQLGDWLDPAappVEPGDARTSGTLVADAYLVHIT 634
                      ********************************************************************999989******************** PP

                      HHHHHHHHHTTS..--HHHHHHHHHHHHHHHHHHB.-TTS-BTT--HHHHHHHHHTT-S-GGGH.HHHHHHHHHHHHHTTS-----TTTHHHHH CS
  Bac_rhamnosid6H 180 klvakiaellgkeedakkyaalaeelkaafnkkyldsetgsvandtqtanalpLafglvpeaeraakvaerlvkkveenknhlstGfvGtpill 273
                        ++ki+++l+++++a++++a+ ++lka+f++ky+ +++g +  dtqta++l+++ +l+ ++e+a+++a+rlv+ v+++k++++tGf+Gtpi+ 
       EEA21078.1 635 YVMSKISKALDQDQNAARFEADHDRLKAKFQAKYI-APSGLLVGDTQTALSLAIMYDLHSTPEQATAAASRLVQLVRQAKFRVATGFAGTPIIA 727
                      ***********************************.********************************************************** PP

                      HHHHHTT-HHHHHHHHH--SSSSSHHHHHTT-SS--SSTTSB-.....--TTS--S--SGGGGGHHHHHHHT CS
  Bac_rhamnosid6H 274 rvLsengeedlayalllqeeypswgymvknGaTtiwErWdsml.....npkemnSfnHyalgavaewlyenv 340
                      ++L+++g++++ay++l+++++psw+y++++GaTt+wErWdsml     np+em+SfnHyalg++++wl+++v
       EEA21078.1 728 HALTKSGYPQIAYRMLQEKNRPSWMYPITMGATTVWERWDSMLpdgsiNPGEMTSFNHYALGSIINWLHSTV 799
                      *********************************************************************986 PP

>> Bac_rhamnosid_N  Alpha-L-rhamnosidase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  184.4   0.0   3.4e-58   1.5e-54       2     172 .]     155     330 ..     154     330 .. 0.95

  Alignments for each domain:
  == domain 1  score: 184.4 bits;  conditional E-value: 3.4e-58
                      -EEEEEEEEEEESEEEEEETTEE-SSBSSBT----TTTEEEEEEEE-TTT--S.EEEEEEEEEE-HHHHS--TTS...S-SS-SS-EEEEEEEE CS
  Bac_rhamnosid_N   2 kikrarlyitaLGvyelelNGkrvgdevLaPgwtdyrkrvqyqtyDvtsllre.geNaigvlvgeGwyagrvgfgekrrstygkepallaqlev 94 
                      ++++arlyit+ Gvy++++NG+ vgd++LaPgwt+yr+r++yq++Dvt+ll++ g N+i+v+v+eGwy++r+gf+++rr++yg+++a laqle+
       EEA21078.1 155 TVETARLYITSFGVYRAFINGHLVGDQCLAPGWTSYRHRLNYQVFDVTPLLNDeGPNVIAVEVAEGWYTTRLGFRGGRRQIYGDRLAALAQLEI 248
                      6899***********************************************987**************************************** PP

                      EETTS-EEEEE-STT-EEE--SEEEEETTTEEEEEGGG--TTTT....STT---TTSEE-EE--S--SEEEE--S--EEEEE CS
  Bac_rhamnosid_N  95 eyedgtkeviatdtsWkvtegpiteseiydGEtyDarkeikgws....epgfddskwnpvkvlkvpegkleaqeappvrvte 172
                      +   + +  + td++W++t ++i +se+ydGE yD r+e + w+    ep+++   w  v++l++p ++l+a++appvr+te
       EEA21078.1 249 QLGPEDRFSVCTDSTWTCTPSAIVRSELYDGEVYDTREENTTWNcrglEPSVEGLGWVAVRELDFPIATLVAPDAPPVRITE 330
                      *******************************************9444455666789***********************986 PP

>> Bac_rhamnosid  Bacterial alpha-L-rhamnosidase concanavalin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.4   0.0   2.7e-29   1.2e-25       2     100 ..     339     440 ..     338     442 .. 0.89

  Alignments for each domain:
  == domain 1  score: 89.4 bits;  conditional E-value: 2.7e-29
                    EEETTEEEEEEEEEEEEEEEEE.E---TT-EEEEEEESEE-TTS-EE-GGGTT---EEEEE----SSEEE--SS--EEEEEEEEES-SS-...--G CS
  Bac_rhamnosid   2 klkdgttvlDlGqnlaGvirlk.vkgeeGtevklrfgEvLeddgevdtrnlrkakatdeyilkGreeeawqpsftfhGfrYveieglade...lad 93 
                    k+++g+tv+D+Gqnl+G++r++  +++ G+++++ ++EvLe +ge+ tr lr+ak+tde+il+G e   w+p++tfhGfrYv+++g+ +e      
     EEA21078.1 339 KTPSGKTVVDFGQNLVGRLRVRsLTQPVGSRLSFIHAEVLE-HGELGTRPLRHAKCTDEIILNGAEILDWSPQYTFHGFRYVQVNGWDEEqdgSLL 433
                    7899******************99*****************.*********************************************555344333 PP

                    GGEEEEE CS
  Bac_rhamnosid  94 esltglv 100
                     +l +lv
     EEA21078.1 434 VNLRALV 440
                    3355555 PP

>> DUF3344  Protein of unknown function (DUF3344)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.0   0.00017      0.77      45      70 ..     146     170 ..     138     176 .. 0.85
   2 !    4.7   0.0    0.0043        19     228     266 ..     178     219 ..     170     228 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00017
     DUF3344  45 ktftlPegaevkwArlYvyytwsvyg 70 
                 k ftlP +++v+ ArlY+  +++vy 
  EEA21078.1 146 KPFTLPTASTVETARLYI-TSFGVYR 170
                 669***************.7777775 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.0043
     DUF3344 228 lad.....vgstegsyvgiesfdVtsylkssggdNtlgyqresg 266
                 ++d     ++++    +++++fdVt++l++ +g N ++++   +
  EEA21078.1 178 VGDqclapGWTSYRHRLNYQVFDVTPLLND-EGPNVIAVEV-AE 219
                 555555556677777899**********99.6799998887.34 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (810 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       418  (0.0233142); expected 358.6 (0.02)
Passed bias filter:                      389  (0.0216967); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.64u 0.27s 00:00:00.91 Elapsed: 00:00:00.43
# Mc/sec: 5712.73
//
Query:       EEA21079.1  [L=504]
Description: hexose carrier protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.6e-88  295.5  29.1    7.5e-88  295.4  29.1    1.0  1  Sugar_tr  Sugar (and other) transporter
    2.7e-30  105.5  33.1    2.7e-30  105.5  33.1    1.9  2  MFS_1     Major Facilitator Superfamily
    0.00035   19.1   2.0    0.00035   19.1   2.0    2.5  3  TRI12     Fungal trichothecene efflux pump (TRI12)


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  295.4  29.1   1.3e-91   7.5e-88       2     452 .]      10     464 ..       9     464 .. 0.92

  Alignments for each domain:
  == domain 1  score: 295.4 bits;  conditional E-value: 1.3e-91
                 HHHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTS CS
    Sugar_tr   2 alvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgkn 100
                 alv+algg+++g d+g+i+++l+     +++++   ++ ++    l+g+ivs+++vG+++G + ag+ ++rf+R+ ++ ++av+++ ga lq aa    
  EEA21079.1  10 ALVVALGGFVYGVDSGIIATTLNHDT--FKHCMLGPTGVNAP---LTGAIVSLYNVGQAVGTFAAGYSANRFSRRRTICASAVIAILGATLQCAAV--- 100
                 79******************999988..66666666665664...9**************************************************... PP

                 S-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHH CS
    Sugar_tr 101 svevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPrylv 199
                 +  ++i+gR+++G+g+G++ ++vP+yi+E++p+k Rg++v+l+ ++i++G++ a ++g+g ++ +++ +wri+l++q+  +l+l+i+ +f+P SPr+l+
  EEA21079.1 101 NPGMMIAGRLFAGMGCGIILTIVPIYIAEVSPPKQRGMIVGLQGFMIAIGFFAANWIGYGGAYAKGDAQWRIPLAMQIPGPLALAIGCCFVPYSPRWLI 199
                 9************************************************************************************************** PP

                 HTT-HHHHHHHHHHHHHC.....HHHHHHHHHHHHHHHHHHH........HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH. CS
    Sugar_tr 200 ekgkeeeakevlaklrge.....edadrelaeekdsleaeqeee...kaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsks. 289
                 +++++eea+ vl  + g+     + + +ela + ++++ e ++       + +lls+  ++ r+l+++ + ++ q++G  +i +y  +++  +g++ + 
  EEA21079.1 200 QQERYEEARVVLTAIHGNshdndDVVGQELAHIRAQIHVEATQVtsfRLAVTNLLSR-RYLHRTLMACFILVMGQFSGSSVIQNYQGSFYAAVGFTGKt 297
                 **************8888644444445555566666655544337777777778777.68***********************************9999 PP

                 .HHHHHHHHHHHHHHHHHH.HHHHHHS-SHHHHHHHHHHHHHHHHHHH...HHHHTTSS.....CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTT CS
    Sugar_tr 290 .llvtiivgvvnfvatfva.iflvdrfGRRtllllGaagmaicfvilg.ivalllvaks..kaasivaivfialfialfalgwgpvpwvlvsElfpqsv 383
                  ll+++i+g + ++   +  +   d++ R ++l +G+++ +i+ +i     a  ++a+s   + s +ai++i+l+ + +a+ ++ ++wv+ sElfp  +
  EEA21079.1 298 sLLISGIYGLMGVLGQEIYlFIAADKWPRTRTLWVGSVFLSIMIAICMaLSASYGSASSgnISGSRAAIAMIFLYSCGYAVFFNATIWVVPSELFPFFL 396
                 9*************9999946789************9999998888775566777777688899*********************************** PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 384 Rskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 Rs+++ +av+++ +a ++ s+++p+++++++ + ++ +f + + +++++ ff +pet g++leei elf
  EEA21079.1 397 RSTGMGLAVFSKAVAAIILSQITPTALQNVS-WRYYSLFIASNFVAAFVYFFLLPETGGKSLEEIAELF 464
                 *******************************.**********************************987 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  105.5  33.1   4.5e-34   2.7e-30       2     351 ..      14     414 ..       7     416 .. 0.78
   2 !    5.6   1.9    0.0011       6.6     119     187 ..     397     462 ..     397     500 .. 0.75

  Alignments for each domain:
  == domain 1  score: 105.5 bits;  conditional E-value: 4.5e-34
       MFS_1   2 llaaflsalarsilgpal......plalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfasslw.lllvlr 92 
                 +l++f+++ +++i++++l        ++    g+++   g +++ly +g+av+++ +G+ ++rf+rrr++++++++ +lg +l ++  +  + +++++r
  EEA21079.1  14 ALGGFVYGVDSGIIATTLnhdtfkH-CMLGPTGVNAPLTGAIVSLYNVGQAVGTFAAGYSANRFSRRRTICASAVIAILGaTLQCA--AVNPgMMIAGR 109
                 7888999999999888885555433.5566678***********************************************444444..55677****** PP

       MFS_1  93 vlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg...Wravfyilaivsllafv.lfllllpeepperkrkspkee 187
                 +++G+g+g++++++ ++ia+++p+++rg+ +gl + ++++G+  +  +g   a + g   Wr +  +  +  l +++ +  +++p +p+    ++  ee
  EEA21079.1 110 LFAGMGCGIILTIVPIYIAEVSPPKQRGMIVGLQGFMIAIGFFAANWIGYGGAYAKGdaqWRIPLAMQIPGPLALAIgC--CFVPYSPRWLIQQERYEE 206
                 *********************************************9999987755556889988777777777766633..777666666666666666 PP

       MFS_1 188 e...............................kgtgpaplvpawkallkdpvlw.illialllfffgfsg....lltllplylqevlglsglllaglll 250
                                                 + t+ ++++ a + ll++++l   l+++++l+ +g ++    +  +  ++     g++g  +++l++
  EEA21079.1 207 ArvvltaihgnshdnddvvgqelahiraqihvEATQVTSFRLAVTNLLSRRYLHrTLMACFILV-MGQFSgssvIQNYQGSF-YAAVGFTG-KTSLLIS 302
                 6999******999999998888888866655544444444447888888887743355555555.45555255566666665.88888887.8888889 PP

       MFS_1 251 allalvgailallagrls.drlgr.rrrlllallllllaalglallavt........ssavllllvlvliGfglgfv.fpsllalasdlappeeagtas 338
                 ++++l+g+ ++ +  +++ d+++r r+ ++ +++l +++a+++al a +        s + +++++++l+++g++++ +++++++ s+l+p   + t +
  EEA21079.1 303 GIYGLMGVLGQEIYLFIAaDKWPRtRTLWVGSVFLSIMIAICMALSASYgsassgniSGSRAAIAMIFLYSCGYAVFfNATIWVVPSELFPFFLRSTGM 401
                 9999999999555555555**999555555566666666777777777766666665555555559999***777766********************* PP

       MFS_1 339 glfntagslggal 351
                 gl+ +  ++++++
  EEA21079.1 402 GLAVFSKAVAAII 414
                 ********99987 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0011
       MFS_1 119 rgraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkee 187
                 r+ ++gl+  + +++ai+   + +  +++++Wr+  +++a  ++ afv    +++ +++  k  +++ e
  EEA21079.1 397 RSTGMGLAVFSKAVAAIILSQITPTALQNVSWRYYSLFIASNFVAAFV---YFFLLPETGGKSLEEIAE 462
                 7889999999999999999999999999*****988888888888877...555555555554444444 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   2.0   5.8e-08   0.00035      83     164 ..      54     136 ..      44     201 .. 0.80
   2 ?   -1.9   0.1      0.14   8.1e+02     376     399 ..     229     252 ..     224     273 .. 0.83
   3 ?   -0.5   1.8      0.05     3e+02     386     480 ..     343     442 ..     326     478 .. 0.71

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 5.8e-08
       TRI12  83 fstlwttgqavsilvmgrltdrfgrrpfvilthilglvgaivgctatkfntllaamtllgvaagpa.gasplfvgelmsnktk 164
                 + +l+ +gqav  +  g  ++rf rr  + ++ ++ ++ga + c+a +   ++a   + g+ +g      p+++ e+   k +
  EEA21079.1  54 IVSLYNVGQAVGTFAAGYSANRFSRRRTICASAVIAILGATLQCAAVNPGMMIAGRLFAGMGCGIIlTIVPIYIAEVSPPKQR 136
                 56799*********************************************************998625689999999876654 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.14
       TRI12 376 vrhirwqilvgalwltaflgamss 399
                 + hir qi v a  +t+f  a++ 
  EEA21079.1 229 LAHIRAQIHVEATQVTSFRLAVTN 252
                 57***************9877664 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 0.05
       TRI12 386 galwltaflgamssvnrdnknaaialsvl..sgfvvawaqditml...lvqfittdedlgvafavvaaarpfagsiftaafislysnrypkelashlss 479
                  ++ l+a  g+ ss n     aaia+ +l  +g+ v +   i ++   l  f      +g+a+   a a  ++  i  +a+  +    y   +as + +
  EEA21079.1 343 ICMALSASYGSASSGNISGSRAAIAMIFLysCGYAVFFNATIWVVpseLFPFFLRSTGMGLAVFSKAVAAIILSQITPTALQNVSWRYYSLFIASNFVA 441
                 357899999999999999999999998874357777777776654333556667777777776666666667777777777777666666666666655 PP

       TRI12 480 a 480
                 a
  EEA21079.1 442 A 442
                 5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (504 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       778  (0.0433934); expected 358.6 (0.02)
Passed bias filter:                      388  (0.0216409); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.30s 00:00:00.89 Elapsed: 00:00:00.45
# Mc/sec: 3394.67
//
Query:       EEA21080.1  [L=588]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.7e-10   39.7   0.8    4.7e-10   38.9   0.8    1.5  1  Fungal_trans  Fungal specific transcription factor domain
     0.0014   18.7   7.0     0.0031   17.6   7.0    1.6  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.031   14.2   0.0      0.069   13.1   0.0    1.5  1  ComX          Bacillus competence pheromone ComX


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.9   0.8   7.9e-14   4.7e-10       3     265 ..      86     319 ..      84     369 .. 0.80

  Alignments for each domain:
  == domain 1  score: 38.9 bits;  conditional E-value: 7.9e-14
  Fungal_trans   3 rffsnfh.pqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeili...hedfsspssslwilq 95 
                   ++f ++h    +++h+psf++        k   as + ++a++al+a++s ++  ++ s+  + +  ++    +a   i   he ++sps  l+++q
    EEA21080.1  86 LYFHYIHnIAHTVFHEPSFMHRL------KEGRASMIHIYAMCALAARYSTNRIFSNVSPCARGK-LYA---TEA---IrrcHERMVSPS--LETVQ 167
                   699999955559***********......*************************99977777766.333...233...233366666655..6**** PP

  Fungal_trans  96 sLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddl 192
                    +ll+ +y ++ +++ +   ++g+a       +Lh +  + ++    + ++  +e++rR+w+++ +   + a+++   p+ + +   +pLP+ dd  
    EEA21080.1 168 GFLLIGYYFSGEGSIQGKHTYVGLA-------RLHADLLSPED----TPTVVLREELRRTWLSIHIASHWSASDMETEPT-NPFHGPVPLPKIDD-A 251
                   *************************.......45555444443....355556888***********************7.9*************.6 PP

  Fungal_trans 193 wesddaseetlvetklsneeksrkiasfllaLkkilsk...iagsllsiekqlqqrdlqseklswveeleraldnW 265
                   ++++  s        l ++ +++++  ++ +  +i  k   +++ +ls    +  ++           le++ld+W
    EEA21080.1 252 DFHTLGSDLLTET--LASPITRCDMWAQMARTLNIFTKinvLLR-HLSKDEISFDKYCT-----EAAVLEHSLDQW 319
                   6666555555444..46788888888888888888888564344.55555555555444.....556666666666 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   7.0   5.2e-07    0.0031       2      35 ..      13      47 ..      12      52 .. 0.83

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 5.2e-07
                S-HHHHHCT---ST..SSSS-HHHHHCTHHHCCCCT CS
     Zn_clus  2 aCdnCrkkKvKCda..kkPaCsnCkklnleCtfyse 35
                +C +Cr +K++C    k   C+ C++l+++C+  ++
  EEA21080.1 13 SCATCRARKRRCIPsfKWDGCQLCQSLSSPCS-LRQ 47
                8***********87665555***********9.655 PP

>> ComX  Bacillus competence pheromone ComX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   1.1e-05     0.069       5      32 ..      94     121 ..      91     126 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.1e-05
        ComX   5 vVekLvenPdvleklqeGklsLvGlset 32 
                 +  +   +P+++ +l+eG +s++++ ++
  EEA21080.1  94 IAHTVFHEPSFMHRLKEGRASMIHIYAM 121
                 66667789****************9776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (588 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       424  (0.0236488); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.56u 0.24s 00:00:00.80 Elapsed: 00:00:00.41
# Mc/sec: 4279.92
//
Query:       EEA21081.1  [L=308]
Description: F-box domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.2e-08   32.7   1.1      1e-07   31.7   1.1    1.5  1  F-box-like  F-box-like
    0.00031   20.6   0.5    0.00073   19.4   0.1    1.7  2  F-box_4     F-box
     0.0041   17.0   0.3     0.0041   17.0   0.3    1.8  2  F-box       F-box domain


Domain annotation for each model (and alignments):
>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.7   1.1   1.7e-11     1e-07       3      43 ..      14      53 ..      12      58 .. 0.87

  Alignments for each domain:
  == domain 1  score: 31.7 bits;  conditional E-value: 1.7e-11
  F-box-like  3 rLPdEiLlqIFsyLppsdLlrlalVCrrWrrvaldtplLWr 43
                 LP+EiL+qI+  L ++ Ll+la V+ r+++v+l+  l +r
  EEA21081.1 14 TLPNEILVQILNPLATRALLPLASVSHRFHDVVLRI-LHYR 53
                6********************************876.4444 PP

>> F-box_4  F-box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.1   1.2e-07   0.00073       4      49 ..      11      56 ..       8      64 .. 0.92
   2 ?   -1.8   0.0      0.46   2.8e+03      24      61 ..     168     207 ..     159     216 .. 0.67

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 1.2e-07
     F-box_4  4 sLssLPlevlqhiaslLDsfsLsqLslvskllrevcssllqergiV 49
                 L +LP e+l +i++ L   +L+ L+ vs+++ +v  ++l+ r + 
  EEA21081.1 11 PLYTLPNEILVQILNPLATRALLPLASVSHRFHDVVLRILHYRLLL 56
                6889*************************************99876 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.46
     F-box_4  24 sLsqLslvskllrevcssllqergi..VllkWekkkyskg 61 
                 s+++L ++    r + s +  e gi  V   W k+k +k+
  EEA21081.1 168 SIVNLVKIMPNSRILISAVTVEDGIirVWRDWLKRKAKKD 207
                 6667777777777777777777777334557888877765 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.3   6.8e-07    0.0041       4      40 ..      13      49 ..      10      56 .. 0.89
   2 ?   -4.3   0.3         3   1.8e+04      33      39 ..     196     202 ..     196     204 .. 0.84

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 6.8e-07
                HHS-HHHHHHHHHTS-HHHHHHHCTT-HHHHHHHTTH CS
       F-box  4 srLPsevlrhILerLplsdllalrrVSkgwrilidsd 40
                  LP+e+l +IL  L ++ ll l++VS ++++++ ++
  EEA21081.1 13 YTLPNEILVQILNPLATRALLPLASVSHRFHDVVLRI 49
                569*****************************99877 PP

  == domain 2  score: -4.3 bits;  conditional E-value: 3
                 HHHHHTT CS
       F-box  33 wrilids 39 
                 wr+++++
  EEA21081.1 196 WRDWLKR 202
                 9999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (308 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       512  (0.0285571); expected 358.6 (0.02)
Passed bias filter:                      381  (0.0212505); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.41u 0.24s 00:00:00.64 Elapsed: 00:00:00.37
# Mc/sec: 2483.58
//
Query:       EEA21082.1  [L=724]
Description: acetylglutamate synthase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      8e-49  165.6   0.0    1.8e-48  164.4   0.0    1.5  1  NAT       NAT, N-acetyltransferase, of N-acetylglutamate synt


Domain annotation for each model (and alignments):
>> NAT  NAT, N-acetyltransferase, of N-acetylglutamate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  164.4   0.0     1e-52   1.8e-48      12     160 ..     515     702 ..     509     713 .. 0.92

  Alignments for each domain:
  == domain 1  score: 164.4 bits;  conditional E-value: 1e-52
                 SSEEEE---XEEEESSCCCS..................SXCCHHHHHHTTSTTTSSXHHHHHHHHHTSXEEEEEETTXSEEEEE.....EXSS...... CS
         NAT  12 agtlirrGlkvitvkslkel..................idlekLksliedsfkrkldvkdYldrlkgkiakiyiaedyeglAivtwedpkeek...... 86 
                 + t+++rG++++  ++++                    idl++L +liedsf+rkldv+dYl+r++g++a+ +ia++yeg Ai+twe+p + +      
  EEA21082.1 515 QSTFLKRGMPLTILPDPRITpwspnspdsrhltlddprIDLSRLVHLIEDSFNRKLDVQDYLNRVNGRLAGLIIAGEYEGGAILTWETPPSIPesernn 613
                 579**************9999*******************************************************************988778999** PP

                 ......SSXEEEEEEEXHHHHHT.THHHHHHHHH.HHHXSS.EEEEEETTXTTHHHHHHCXSEEEE..ETTEEEEEES....XXXHHHH CS
         NAT  87 ......evayLdkFavlkssqgs.gvsdvvfkal.kkdfpk.LvWrsrednpvnkWyfersdGslk..ksqwvlfWyG....lkdlkev 160
                        v+yLdkFavlk+sqg  gv+d+vf+a+ ++  p+ ++Wrsr dnpvnkWyfers G++k  +s+w +fW++     +d+ + 
  EEA21082.1 614 penlprLVPYLDKFAVLKRSQGAgGVADIVFNAMvRTCLPQgVCWRSRMDNPVNKWYFERSRGTWKldGSNWAMFWTTpgvpEEDSLRF 702
                 **********************************9999****************************99*********977664444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (724 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       428  (0.0238719); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.43
# Mc/sec: 5040.60
//
Query:       EEA21083.1  [L=318]
Description: 6-phosphogluconate dehydrogenase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-29  103.5   0.0      2e-29  102.8   0.0    1.3  1  NAD_binding_2    NAD binding domain of 6-phosphogluconate deh
    3.4e-09   37.0   0.0    1.4e-08   35.0   0.0    2.1  1  NAD_binding_11   NAD-binding of NADP-dependent 3-hydroxyisobu
    2.5e-08   34.1   0.0    4.5e-08   33.3   0.0    1.4  1  Shikimate_DH     Shikimate / quinate 5-dehydrogenase
    9.5e-08   32.5   0.0    1.8e-07   31.6   0.0    1.5  1  F420_oxidored    NADP oxidoreductase coenzyme F420-dependent
     0.0018   17.3   0.0       0.06   12.3   0.0    2.2  2  OCD_Mu_crystall  Ornithine cyclodeaminase/mu-crystallin famil


Domain annotation for each model (and alignments):
>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.8   0.0   5.5e-33     2e-29       2     144 ..       4     156 ..       3     168 .. 0.90

  Alignments for each domain:
  == domain 1  score: 102.8 bits;  conditional E-value: 5.5e-33
                    EEEE--SHHHHHHHHHHHHTT-...EEEEE-SSHHHHHHHHHTT.....EEE-SSHHHHHHHCSEEEE-SSSHHHHHHHHHSHCCC-..-TT-EEE CS
  NAD_binding_2   2 igfiGlGvMGsnmalnllkagy...kvavynrtkekveelvaeg.....akaaesieelvasldvvitmvkagkavdevieglleal..kkgdili 87 
                    +++iGlG+MG+ m +nl+++g     + +ynrt +k+e+ + +      aka+ +i+e+v+  d+++t+v +++av+e+ +  l+     +g++++
     EEA21083.1   4 LAYIGLGNMGRGMTKNLVEKGSlssPILLYNRTFSKAESHALTLggsshAKAVRTIAEAVSPSDIIFTCVGDDAAVEEIFNTALKDGedVSGKLFV 99 
                    799***************999533389*******999988877446888*********************************666552358***** PP

                    E-S---HHHHHHHHHHHHHTT-EEEEEEEESHHHHHHHT-EEEEEEE-HHHHHHHHH CS
  NAD_binding_2  88 dgstsspedtrelakelkekglkfldaPVSGGeegAekGtLsimvGGseeafervkp 144
                    d+st++p+++r+l+++++++g++f+ +PV G  + Ae+G+L +++GG++++++r+ p
     EEA21083.1 100 DMSTIHPDTSRKLYTQISARGARFVSCPVFGVPAMAEAGQLICVLGGDKADIQRILP 156
                    *****************************************************9987 PP

>> NAD_binding_11  NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.0   0.0   3.9e-12   1.4e-08       1     119 [.     184     303 ..     184     306 .. 0.88

  Alignments for each domain:
  == domain 1  score: 35.0 bits;  conditional E-value: 3.9e-12
  NAD_binding_11   1 GaGqavKlvnnlllainlaaasEalvlaekaGldpekvlevinassgrsnalenklpqrvlsrdfd....pgFaldlmlKDlglalelareagap 91 
                     G+++++Kl+ n  +   +  ++E+++laek G+ +e + + ++    +   l ++++ r+ ++d+     p F++dl +KDl+ + ++a + g++
      EEA21083.1 184 GKASTMKLIGNSFILSFVEQLAEGMTLAEKSGVGIEPLAQWMELMFPGP--LPKYVE-RMRTGDYYkreyPLFQVDLARKDLRHVSSVAAQSGMK 275
                     8899********************************9999999887665..666666.56666664222256*********************** PP

  NAD_binding_11  92 lpllalaeqlyaaaaaegggdaDhsaiv 119
                     ++ l+++   ++ ++a+ g++ D + ++
      EEA21083.1 276 MRSLEVVDGYLKDVKAHSGEKGDIAGMY 303
                     ***********************99987 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.3   0.0   1.3e-11   4.5e-08      14     112 ..       3     102 ..       1     111 [. 0.82

  Alignments for each domain:
  == domain 1  score: 33.3 bits;  conditional E-value: 1.3e-11
                   EEEEES-SHHHHHHHHHHHCCT-..CEEEEEESSHHHHHHHHHHHT.ET-EEEEGCGHHHHHHT-SEEEE-SSSSS-SB-HHHHHCCHHH.S....E CS
  Shikimate_DH  14 kvlliGaGemaelvakhLlakgv..kkvvvaNRtlerakelaeelkgeeiealkleelkellaeadvvisataseepilekeeveealkkrk..kpl 106
                   +   iG G+m++ ++k+L++kg     ++  NRt+++a++ a  l+g  ++a+++  + e+++ +d+++++++   ++   e ++ alk+ +  + +
    EEA21083.1   3 QLAYIGLGNMGRGMTKNLVEKGSlsSPILLYNRTFSKAESHALTLGGS-SHAKAVRTIAEAVSPSDIIFTCVGDDAAVE--EIFNTALKDGEdvSGK 96 
                   5667*****************852267999***************888.9**********************9887663..3333333333336788 PP

                   EEEE-- CS
  Shikimate_DH 107 llvDia 112
                   l+vD++
    EEA21083.1  97 LFVDMS 102
                   999987 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.6   0.0   5.1e-11   1.8e-07       2      93 ..       4     100 ..       3     103 .. 0.78

  Alignments for each domain:
  == domain 1  score: 31.6 bits;  conditional E-value: 5.1e-11
                    EEEETTSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC....-EEECECHHHHHHH-SEEEE-S-HHH.HHHHHHHC..GHHHHTTSE CS
  F420_oxidored   2 igiiGaGnmgealasgllaagaqpheivvansrnpekaeelaeelg....vkvtavdneeaaeeadvvvlavkped.veevlsel..akdalkgkl 90 
                    ++ iG Gnmg++++++l+++g   + i+   +r+ +kae+ a +lg    +k+   + +ea++ +d+++ +v   + vee+ + +    ++ +gkl
     EEA21083.1   4 LAYIGLGNMGRGMTKNLVEKGSLSSPIL-LYNRTFSKAESHALTLGgsshAKAVR-TIAEAVSPSDIIFTCVGDDAaVEEIFNTAlkDGEDVSGKL 97 
                    688******************9999999.55***************999877777.89**************755413444443322224455666 PP

                    EEE CS
  F420_oxidored  91 vis 93 
                    +++
     EEA21083.1  98 FVD 100
                    666 PP

>> OCD_Mu_crystall  Ornithine cyclodeaminase/mu-crystallin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.3   0.0   1.7e-05      0.06     132     207 ..       4      79 ..       2     101 .. 0.85
   2 ?    2.7   0.0     0.013        48     211     235 ..     133     157 ..     116     194 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.7e-05
                      EEEE--SHHHHHHHHHHCCCS-.-SEEEEE-SSHHHHHHHHHHCCS.CTT-EEECSCHHHHTTSSEEEE----SS-S CS
  OCD_Mu_crystall 132 laiiGaGvqaetqlealkavld.ikevriydrdeeaaekfaenlqefefevsackseeeavegadivvtvTaakapi 207
                      la iG G + +  ++ l +  +  + + +y+r+ ++ae  a +l + + + +a+   +eav+  di+ t+  ++a +
       EEA21083.1   4 LAYIGLGNMGRGMTKNLVEKGSlSSPILLYNRTFSKAESHALTLGG-SSHAKAVRTIAEAVSPSDIIFTCVGDDAAV 79 
                      8999**********9999999944579*****************98.8999*******************9999843 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.013
                      GGS-TT-EEEE-S--STT--SB-HH CS
  OCD_Mu_crystall 211 ewvkpGahinavgadapgkteLddd 235
                       + ++G++i+ +g+d  + + + + 
       EEA21083.1 133 AMAEAGQLICVLGGDKADIQRILPY 157
                      5889*************99988764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (318 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       351  (0.0195772); expected 358.6 (0.02)
Passed bias filter:                      339  (0.0189079); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 2116.53
//
Query:       EEA21084.1  [L=277]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-30  106.8   0.0    1.4e-30  106.4   0.0    1.1  1  CIA30     Complex I intermediate-associated protein 30 (CIA30


Domain annotation for each model (and alignments):
>> CIA30  Complex I intermediate-associated protein 30 (CIA30)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.4   0.0   7.8e-35   1.4e-30       8     160 .]      17     199 ..       8     199 .. 0.91

  Alignments for each domain:
  == domain 1  score: 106.4 bits;  conditional E-value: 7.8e-35
       CIA30   8 sldkwtllsDrvmGGvStaslklskk..........dktalFsGnlstelinrgGFasvrtkkrkrkldlssyegleLrvk.GDgrkYklnlktesk.. 93 
                 s ++wt+ +Dr +GG+St++++++++          ++ a F+G+l++++++++GFas+r ++++  + l++++gleL +  +Dg++Y ++lk+e    
  EEA21084.1  17 SKQDWTSCDDRIRGGSSTSQISIKPStvhhpstpaySSSAFFHGHLDITTLGGAGFASQRNTTNTLGWHLEKFDGLELIIGkSDGKRYSFILKDEMLpk 115
                 6789*******************988*******99999******************************************77*************889* PP

       CIA30  94 .....eqsglsyqadfetk.kge.wetvk......ipfsdfvptfrGrvvedqee.ldlskiksigllls...dkqegpfeLei 160
                      eqs+l+++ +f ++ ++e +e ++      +++ dfvpt+rG++ e  ++ +++++ik++ l+++   + q+g+fe+e+
  EEA21084.1 116 rpdgrEQSSLNWEFEFVVPsPKEgEEGMRagtvlrVKWCDFVPTYRGKPKEGLSRrIAANNIKRVTLMMRsffGMQSGDFEVEV 199
                 *****************876555455555888888**************9987544**************99999******997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (277 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       406  (0.0226449); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.25s 00:00:00.65 Elapsed: 00:00:00.39
# Mc/sec: 2119.63
//
Query:       EEA21085.1  [L=1269]
Description: hypothetical protein PMAA_048880 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1269 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3818  (0.212951); expected 358.6 (0.02)
Passed bias filter:                      493  (0.0274974); expected 358.6 (0.02)
Passed Vit filter:                       120  (0.00669307); expected 17.9 (0.001)
Passed Fwd filter:                        29  (0.00161749); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 1.41u 0.41s 00:00:01.81 Elapsed: 00:00:00.62
# Mc/sec: 6204.98
//
Query:       EEA21086.1  [L=523]
Description: autophagy protein (Atg22), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.6e-134  449.2  27.0   1.9e-134  448.9  27.0    1.0  1  ATG22     Vacuole effluxer Atg22 like


Domain annotation for each model (and alignments):
>> ATG22  Vacuole effluxer Atg22 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  448.9  27.0    1e-138  1.9e-134       1     478 []      43     508 ..      43     508 .. 0.98

  Alignments for each domain:
  == domain 1  score: 448.9 bits;  conditional E-value: 1e-138
       ATG22   1 ttkkellgWylyafaaevfavvavgsfvPllleqlarenGvllsdksapCsakgdeqcvvkflgieidtaSfvlytfslsvllqavvvislsglADygn 99 
                 t++ke++++y+y+++++ ++++   +f+P+++++l+++ +           +    +  ++f+g  ++++S+vl+++++s+++q+vv+++++++AD+g+
  EEA21086.1  43 TSRKEIWSYYAYYIGNNGLTLF---NFAPTAFQNLLYQAAD----------S----NSQLYFAGKLRSINSIVLLCNGISFAIQIVVFLIIGSFADFGT 124
                 79********************...************8887..........1....3569*************************************** PP

       ATG22 100 yrknlLlafaligslstilfllv.tpkkYllgavlyivsntcfgaslvllnsfLPllvredpelqeaeeeeeeeeessetaeeeeskelklstriSslG 197
                 +r+n+L+ ++l+++++++++l+v + +k+ +++ lyiv++++++++l+++++++P l+r+++e+++a++e  ++   s t++e++ +++++++++S+++
  EEA21086.1 125 WRPNILIGLSLVAWAIGFAWLGVhDATKWEAATGLYIVGLIAYQTTLTFWTAAFPGLARNTAEMKRAADELVSG---SITRDEYDFADTMKRSQLSNIA 220
                 ***********************99***************************************9999999988...********************** PP

       ATG22 198 laigylgailvqiisilivialgsta.....tfslrlalllvGlwWliftipaalllkkrpgpplpkglsyliygwkslgrtlkqarklkdvllfLvaw 291
                 ++i+++g+i++++i++ i+++l+ +a     ++ l++++++++ +Wl+++ip+++++k+rpg++    ++++++g+ +l+++ +q+ +l++ l++L+++
  EEA21086.1 221 FYIQSVGEIFILAIIVGIMFGLDVNAstennNWGLSVLIAFATGVWLLLAIPWFVFEKRRPGQDPA-PRNIIMAGLWQLYHAGRQILQLRQSLIYLIGY 318
                 **********************999999999******************************87743.58****************************** PP

       ATG22 292 fllsdgiatvsstavlfaktelkmstaklillsivaviaavlGaflwplvsrrlnlktkktllaiivlfeliplyGllGiilgkiGlkqpwEfyvlavv 390
                 fll d+++t+++++ +++++ + ++t +l++l iv ++a+ +G++++++v+r+++l+tk+++ +i++ ++l++ +G++Gi+++++G++++wE+++++++
  EEA21086.1 319 FLLGDSLNTTVTVIGTLQNSIVAYNTLQLTYLLIVGIAAQAIGIYVFWFVQRHFHLSTKTMFNVIAIGIILLDGWGMIGIWTQRFGFHNEWEVWLYQAY 417
                 *************************************************************************************************** PP

       ATG22 391 yglvlgglssysRslfseLiPrGkEaaFFsLyaitdkgssvigplivglItDrt..gnirsafvflavLlvvplpll.llvdvergrreae 478
                 ygl++++++sys++++se++PrGkE+ FFsL++i++k+ss+igp+++++I+D+t  gn +++f+fl++L+vv++++l ++vd++++r+e+e
  EEA21086.1 418 YGLFVCPWYSYSQIMISEVTPRGKEFLFFSLFSIIGKTSSFIGPIVSSAIIDATpsGNESTPFYFLFALSVVSFGVLvVFVDLKKSRKEQE 508
                 **************************************************************************99879*********985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (523 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       928  (0.0517597); expected 358.6 (0.02)
Passed bias filter:                      389  (0.0216967); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.33s 00:00:00.93 Elapsed: 00:00:00.48
# Mc/sec: 3300.33
//
Query:       EEA21087.1  [L=394]
Description: actin-binding protein Fragmin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-31  107.9   0.9    2.5e-11   43.3   0.0    3.4  3  Gelsolin  Gelsolin repeat


Domain annotation for each model (and alignments):
>> Gelsolin  Gelsolin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.3   0.0   1.4e-15   2.5e-11      12      76 .]      63     140 ..      52     140 .. 0.94
   2 !   37.5   0.0   8.8e-14   1.6e-09       2      53 ..     187     238 ..     186     261 .. 0.86
   3 !   24.2   0.1   1.3e-09   2.4e-05      11      42 ..     315     346 ..     309     387 .. 0.84

  Alignments for each domain:
  == domain 1  score: 43.3 bits;  conditional E-value: 1.4e-15
                 GGGEETTSEEEEEESS..............EEEEEEHTTSHHHHHHHHHHHHHHHHHCTTTTTSEEEEEETTHHHHHHH CS
    Gelsolin  12 ssslesgdcyLLdngf..............tiflWiGkessqeeknfaadlaaeldseerfplpeliredqgkeparFl 76 
                 ++++++gd+y++++ +              +if+W+G++ +q+e++ aa+ ++eld e +++ + ++re+q + +++Fl
  EEA21087.1  63 YGQFYDGDSYIVLHSYiipragnqperlahDIFFWLGAKTTQDEAGTAAYKTVELD-EYLHGIATQHRETQLHPSEEFL 140
                 79******************************************************.**************99888886 PP

  == domain 2  score: 37.5 bits;  conditional E-value: 8.8e-14
                 CEEEEEBSSSGGGEETTSEEEEEESSEEEEEEHTTSHHHHHHHHHHHHHHHH CS
    Gelsolin   2 svlpkvvklsssslesgdcyLLdngftiflWiGkessqeeknfaadlaaeld 53 
                 sv++ +v+ +++sl++ d+++L + ++i++W+Gk+ss+ ek++aa+  ++l 
  EEA21087.1 187 SVVVHEVEPTWKSLDDADVFVLEKDNKIWVWQGKDSSPMEKAKAAQVVSDLT 238
                 678999****************************************999987 PP

  == domain 3  score: 24.2 bits;  conditional E-value: 1.3e-09
                 SGGGEETTSEEEEEESSEEEEEEHTTSHHHHH CS
    Gelsolin  11 sssslesgdcyLLdngftiflWiGkessqeek 42 
                  +s+l+s+d+++ d+g++i++W G++ s+e +
  EEA21087.1 315 RVSDLDSNDVFIFDTGKKIWVWEGQNTSPEVR 346
                 5799**********************888755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (394 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       413  (0.0230353); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2573.54
//
Query:       EEA21088.1  [L=513]
Description: N-alkane-inducible cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.5e-63  214.4   0.0    3.3e-63  214.1   0.0    1.0  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  214.1   0.0   1.8e-67   3.3e-63       1     445 [.      53     490 ..      53     506 .. 0.84

  Alignments for each domain:
  == domain 1  score: 214.1 bits;  conditional E-value: 1.8e-67
                 --SESEHHCCHCHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHH CS
        p450   1 PpgptplplvgnllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkklR 99 
                 P+gp  + ++  + + +r++ + + +++l k+ygp+f+ k  s +v + ++pe +k++l  + ++f   ++    +t   p +g g+++a+g++w   R
  EEA21088.1  53 PSGPFGIGFFLQVAKAAREGRRIQLHDSLYKTYGPTFNQKTPSNDVLFTIDPENIKAILTSQFNDFGLGHR---AKT-FWPLLGDGIFNADGQMWSHAR 147
                 6777778888888888888899999*************************************655544333...333.3389***************** PP

                 HHHHHHHTSHSTTTHHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSH.....HHHHHHHHHHHHHHHHCHHHHCCC CS
        p450 100 rfltptltsfgklsleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledek.....lselvkaveelssllskssvqlll 193
                 ++l p++t++ + +  +l++e + d+++k+ k+ g+   +di++l++ ++ d+++  lFg+++  + ++      + e+ +a+++ +++  +++     
  EEA21088.1 148 TLLRPQFTKD-QVADLQLMDEHITDFLAKIPKD-GSL--FDIQPLFFSFTNDSSTHFLFGESLA-NSKNAagrsdAAEFGRAFDKSLEWI-SRR----- 235
                 ********99.66889*************9664.555..8*********************976.4444356555667777777776666.333..... PP

                 CCH.HHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHC.SCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        p450 194 lfp.llkylptkllrklkeavkklkdlldklieerretldsa.kksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLa 290
                  ++   + ++   ++++ +a+k+++d++d+++    e+ +++  ++r+ fl+al +++         + + l+ ++l+ll+aG dTt+s ls +L++L 
  EEA21088.1 236 -ISaQKLSFLVDGNKEYTSACKYVHDIADHYVCIALESRKNTkVSDRYVFLQALANDT--------QDPKVLRDNILNLLIAGRDTTASLLSSVLFYLS 325
                 .222333466778889999999999999999887777777775456888888888885........36789**************************** PP

                 HSHHHHHHHHHHHHHHCCTTT....T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEETT.........EEE-TT-EEEEEHHHHHT-TTT CS
        p450 291 knPevqeklreEidevlgdkr....eptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirg.........ylipkGtevivnlyalhrdpev 376
                 + P + ++lr Ei    gd+     e+t++ ++++ yl+ v++E+LRl p+vp   +R+ ++d++++           +++k+t++ ++ly +hr+ ++
  EEA21088.1 326 HAPAIWKRLRREIIDEYGDAAhptgEITHANIKNMRYLRYVLNEALRLLPPVP-INSRMSFRDTSLPRgggpdgkgpIFVKKDTVIPFSLYRMHRRTDI 423
                 *************999999888999****************************.777*********7334566688*********************** PP

                 S.SSTTS--GGGGB-TTSCTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGE CS
        p450 377 f.pnPeeFdpeRFldekgnskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdppp 445
                 + p++eeF+peR++++     +k  +++PF  GpR+C+G++ A  e +++l++l qnF+   +++++p p
  EEA21088.1 424 WgPDAEEFRPERWEENAS---SKTWEYIPFNGGPRICLGQQYALIEASYMLIRLAQNFDTLENDGGSPVP 490
                 **************9965...8*************************************99766555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (513 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       496  (0.0276647); expected 358.6 (0.02)
Passed bias filter:                      492  (0.0274416); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.28s 00:00:00.90 Elapsed: 00:00:00.46
# Mc/sec: 3319.77
//
Query:       EEA21089.1  [L=493]
Description: FAD binding domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      3e-16   59.4   0.0    4.9e-16   58.7   0.0    1.3  1  FAD_binding_4  FAD binding domain


Domain annotation for each model (and alignments):
>> FAD_binding_4  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.7   0.0   2.7e-20   4.9e-16      11     137 ..       9     134 ..       6     136 .. 0.92

  Alignments for each domain:
  == domain 1  score: 58.7 bits;  conditional E-value: 2.7e-20
                    HHHHHHHHHHHHCTSCEEEESSSTTEESTTCSCCEEEEEETTS--EEEEETTTTEEEEETTSBHHHHHHHHHHHTTECSSGGGTTCGSBHHHTTTT CS
  FAD_binding_4  11 eevaaalrlaneaglpvlvrGgGssllgqavatggvvldlsrlnrileideeegtatveaGvtlgdlvealaakglllglepgsgipgtvGGaiat 106
                    +e+++++   ++ + p +++ g ++ ++  +  +   +d+s+ln++l +d++++ta ve+ v++++lvea+ ++gl+ ++ ++     t+GG  ++
     EEA21089.1   9 KEISRVVSQFHKLNQPYRIFHGSTNSTRPRLGASQNFVDISKLNNVLRVDRSSKTAAVEPNVPMDRLVEATLKHGLVPPVVMEF-PGITAGGGYSG 103
                    799************************666669999***********************************8888888866655.566******** PP

                    T-EETTEEGG--HHGTEEEEEEEETTSEEEE CS
  FAD_binding_4 107 nagGygsekyGlirdnvlglevvladGevvr 137
                     +g + s ++G +  ++ ++e+vla+Gevv+
     EEA21089.1 104 TSGESSSFRHGFFDRTINSVEMVLANGEVVK 134
                    *****************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (493 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       417  (0.0232584); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 3306.92
//
Query:       EEA21090.1  [L=382]
Description: galactose-1-phosphate uridylyltransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.6e-71  239.4   0.5    8.4e-70  234.9   0.1    2.5  3  GalP_UDP_transf  Galactose-1-phosphate uridyl transferase, N-
    3.3e-60  202.6   0.1    1.1e-59  200.9   0.1    1.7  2  GalP_UDP_tr_C    Galactose-1-phosphate uridyl transferase, C-
     0.0048   15.8   0.0       0.37    9.6   0.0    2.5  2  DUF4921          Domain of unknown function (DUF4921)
  ------ inclusion threshold ------
      0.028   15.2   0.0       0.12   13.1   0.0    2.1  2  HIT              HIT domain
       0.17   12.4   0.0       0.45   11.0   0.0    1.7  1  DcpS_C           Scavenger mRNA decapping enzyme C-term bindi


Domain annotation for each model (and alignments):
>> GalP_UDP_transf  Galactose-1-phosphate uridyl transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  234.9   0.1   2.3e-73   8.4e-70       5     184 .]       6     208 ..       2     208 .. 0.94
   2 ?   -2.4   0.0       1.6   5.6e+03     156     167 ..     244     255 ..     233     257 .. 0.77
   3 ?    1.9   0.0     0.072   2.6e+02       5      44 ..     288     327 ..     268     332 .. 0.85

  Alignments for each domain:
  == domain 1  score: 234.9 bits;  conditional E-value: 2.3e-73
  GalP_UDP_transf   5 eddaiyashrrfnpltgewvlvsphrtkrpwqgqqekiskdtlpekDklkcyLcPgnsrangefnpkykstfvftndFpalsedsnyikteai. 97 
                      ++d+   shrrfnpl+g+++lvsphrtkrpwqgqqe++sk+tlpe+D l+cyLcPgn+ra+g+ np+yk+tfvf nd++a++e++ ++++e++ 
       EEA21090.1   6 LNDI---SHRRFNPLRGSYILVSPHRTKRPWQGQQESPSKTTLPEYD-LACYLCPGNTRAQGDANPQYKNTFVFVNDYSAVKEEQADYQPEEKg 95 
                      5667...9***************************************.*****************************************98874 PP

  GalP_UDP_transf  98 aknilfkaepayGrceviifsskheltladlspkdikavvaaWqektae.lka..........................keypkcvlifENkGa 164
                      a++  ++aep+ G+c+v++fss h++tladls+++i +v++aW+e +++ l +                          k+++++++ifENkGa
       EEA21090.1  96 AESFFLRAEPVVGKCYVLTFSSAHNKTLADLSAAEIVPVIDAWTEIYTShL-SpknplaavapathlppeaptasltkpKSQYRYMQIFENKGA 188
                      455889******************************************942.357788889999****************************** PP

  GalP_UDP_transf 165 amgvsnphPHgqiwaeehlp 184
                      amg+snphPHgq+w++++lp
       EEA21090.1 189 AMGCSNPHPHGQVWTTSSLP 208
                      *****************998 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 1.6
  GalP_UDP_transf 156 vlifENkGaamg 167
                        +fEN G+ + 
       EEA21090.1 244 RIVFENDGFVVL 255
                      4699**998765 PP

  == domain 3  score: 1.9 bits;  conditional E-value: 0.072
  GalP_UDP_transf   5 eddaiyashrrfnpltgewvlvsphrtkrpwqgqqekisk 44 
                      + +ai    rr+++l++++   s  + + p++g +e++++
       EEA21090.1 288 LAEAIAEITRRYDNLFETHFPYSMGIHQAPLEGTEEEVEA 327
                      55566677899*******************9999999854 PP

>> GalP_UDP_tr_C  Galactose-1-phosphate uridyl transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0      0.44   1.6e+03      83      99 ..     176     199 ..     111     211 .. 0.68
   2 !  200.9   0.1     3e-63   1.1e-59       2     155 ..     215     371 ..     214     381 .. 0.97

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.44
                    HHHHHHHCT.......S---EEEE CS
  GalP_UDP_tr_C  83 arkydnlfe.......tsfeysmG 99 
                      +y ++fe       +s +++ G
     EEA21090.1 176 QYRYMQIFEnkgaamgCSNPHPHG 199
                    456777777888888888888888 PP

  == domain 2  score: 200.9 bits;  conditional E-value: 3e-63
                    HHHHHHHHHHH.SS-HHHHHHHHHHHH-TTEEEE-SSEEEE--TT--STT-EEEEESS--SSGGG--HHHHHHHHHHHHHHHHHHHHHCTS---EE CS
  GalP_UDP_tr_C   2 ldsfekYfagsngsillhdyvqmelaekervvelkdsflavvpylakWPfevlllrkaevkslaeladeekedlaailkklarkydnlfetsfeys 97 
                    l++ +kY +++ gs++l dyv +e +++er+v ++d f+++ p++a+WPfe+++++k++++ l++l+  ek++la ++ +++r+ydnlfet+f+ys
     EEA21090.1 215 LEQLQKYRSEHRGSHMLGDYVALECQKQERIVFENDGFVVLCPWWATWPFETMIISKTHKRALVDLNTDEKMQLAEAIAEITRRYDNLFETHFPYS 310
                    7899******************************************************************************************** PP

                    EEEE---SCCCTT...TT--EEEEE--BCSSTTEB----THHHHT-EEESS-HHHHHHHHH CS
  GalP_UDP_tr_C  98 mGlhqaplnaeed...nswlHaHfevpllrsatvrkieVGlelLperlrdllaEqaaerlr 155
                    mG+hqapl+++e+   +swlH Hf++pllrsatvrk++VG+e+++e++rd+++Eqa ++lr
     EEA21090.1 311 MGIHQAPLEGTEEeveASWLHLHFYPPLLRSATVRKFLVGYEMMAEPQRDITPEQATTKLR 371
                    **********99989899*****************************************99 PP

>> DUF4921  Domain of unknown function (DUF4921)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.0    0.0001      0.37       5      55 ..      10      60 ..       6      97 .. 0.86
   2 !    3.7   0.0    0.0062        22     217     301 ..     173     263 ..     165     298 .. 0.68

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0001
     DUF4921  5 tikqvnPftGtevWtvpgrgnrPlsekaeetapleeedreeacafcedrkl 55
                  ++ nP+ G+ +   p r++rP + ++e++++ +  + + ac  c  ++ 
  EEA21090.1 10 SHRRFNPLRGSYILVSPHRTKRPWQGQQESPSKTTLPEYDLACYLCPGNTR 60
                56789*****************************************98764 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.0062
     DUF4921 217 rnryvrYvavfqnWLkpaGasfdhlhkqlvaiDergvqaeaeiarlren......PnlynelavdyaakhnlviaendhavafagfGhryp 301
                  + + rY+++f n  +  G s  h h q+ +  +   + + e+++l++        ++  +++     k++ ++ end  v++      +p
  EEA21090.1 173 PKSQYRYMQIFENKGAAMGCSNPHPHGQVWTTSSLPEEPAIELEQLQKYrsehrgSHMLGDYVALECQKQERIVFENDGFVVLCPWWATWP 263
                 566789***********************99998888888888877664111111234444444444566777777877777766655555 PP

>> HIT  HIT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.0      0.93   3.3e+03      26      58 ..     109     141 ..      97     198 .. 0.60
   2 ?   13.1   0.0   3.4e-05      0.12       3      67 ..     240     304 ..     238     337 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.93
                 SSEEEEEESSTGCSGGGCCHHHHHHHHHHHHHH CS
         HIT  26 pghlLvipkkhlselhdlteeelakllsavkkv 58 
                 ++++L    +h ++l dl+++e+  ++ a +++
  EEA21090.1 109 KCYVLTFSSAHNKTLADLSAAEIVPVIDAWTEI 141
                 566666666666666666666555555544444 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 3.4e-05
                 CC-CCEEEE-SSEEEEE-SS-SSSSEEEEEESSTGCSGGGCCHHHHHHHHHHHHHHHHHHHTCTT CS
         HIT   3 eipstvvyeddlvlafldidpkapghlLvipkkhlselhdlteeelakllsavkkvakalqkkfk 67 
                 ++++++v+e+d ++++    +++p  + +i k+h + l dl+ +e ++l +a+ ++ +   + f+
  EEA21090.1 240 QKQERIVFENDGFVVLCPWWATWPFETMIISKTHKRALVDLNTDEKMQLAEAIAEITRRYDNLFE 304
                 567899***************************************************99988773 PP

>> DcpS_C  Scavenger mRNA decapping enzyme C-term binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00013      0.45      11      99 ..     240     334 ..     234     343 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00013
                 SS-B-EEEE-SSEEEEE-SS-SSSEEEEEEESS---SGGG--TTTTTHHHHHHHHHHHHHHHTT-T-EEEEE--SCCCT-........-S-S--EEE CS
      DcpS_C  11 kepervvyedekfvvlkDikpkaklhllvipkrdikslrdLtkehlpllkemrekakkvieekynevdaeelrvgvhyqP........svyhlHlHv 99 
                 +++er+v+e+++fvvl    +  ++  ++i+k + + l dL++++   l+e   ++    ++ +++       +g+h +P          + lHlH+
  EEA21090.1 240 QKQERIVFENDGFVVLCPWWATWPFETMIISKTHKRALVDLNTDEKMQLAEAIAEITRRYDNLFET--HFPYSMGIHQAPlegteeevEASWLHLHF 334
                 5789*************************************8887776666666666555555533..22467888888877777766555566665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (382 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       465  (0.0259356); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2624.42
//
Query:       EEA21091.1  [L=144]
Description: ergosterol biosynthesis protein Erg28, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-40  137.6   3.0    2.4e-40  137.3   3.0    1.0  1  Erg28     Erg28 like protein


Domain annotation for each model (and alignments):
>> Erg28  Erg28 like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.3   3.0   1.3e-44   2.4e-40       1     109 [.      16     128 ..      16     129 .. 0.97

  Alignments for each domain:
  == domain 1  score: 137.3 bits;  conditional E-value: 1.3e-44
       Erg28   1 glLpkwllfvsvvslgnslqnyvtlkltrrvYsgkpk....eqvtplsaRtfgtwtllsaivrlyaaynienkalyqlalltyvialvhflsEllvfkt 95 
                 g+Lp wll+vsv+s++ns+q+y+++ ++++++ g+ +    ++ tpl+aRtfgtwt++sa++r yaayni+n+  y++a++ty ialvhf++E+lv+++
  EEA21091.1  16 GWLPAWLLIVSVISAANSAQSYLSPLYHSQIFIGSRRtnnkSPSTPLAARTFGTWTFVSAVIRAYAAYNIHNPVAYDMAIWTYGIALVHFTTEWLVYGS 114
                 79*******************************977677779********************************************************* PP

       Erg28  96 aklgkgllfpliva 109
                 a+++++++fp+++a
  EEA21091.1 115 AEFRGRIVFPFLFA 128
                 ***********987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (144 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       353  (0.0196888); expected 358.6 (0.02)
Passed bias filter:                      240  (0.0133861); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.26s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 1031.15
//
Query:       EEA21092.1  [L=350]
Description: ketoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.1e-38  131.8   0.0    3.5e-38  131.0   0.0    1.3  1  adh_short        short chain dehydrogenase
    5.2e-22   78.6   0.0    7.1e-22   78.1   0.0    1.1  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    2.6e-05   24.2   0.0    7.2e-05   22.8   0.0    1.8  2  KR               KR domain
    0.00063   19.0   0.0    0.00085   18.5   0.0    1.2  1  Polysacc_synt_2  Polysaccharide biosynthesis protein
  ------ inclusion threshold ------
      0.039   13.9   0.0      0.064   13.2   0.0    1.3  1  T3SS_needle_reg  YopR, type III needle-polymerisation regulat
       0.17   12.5   0.0       0.31   11.7   0.0    1.4  1  F420_oxidored    NADP oxidoreductase coenzyme F420-dependent


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  131.0   0.0   1.2e-41   3.5e-38       2     190 ..      76     268 ..      75     272 .. 0.92

  Alignments for each domain:
  == domain 1  score: 131.0 bits;  conditional E-value: 1.2e-41
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT..TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---S..S--SSGGGC CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee..gakalaiqvDvtdreevealvekavkklgkldvLvnNAGi..tgsgpfsel 96 
                 ++l+tGas+G+G+++a ++a++G++v++v+r+e+kl  +a+e+k++  +++  ++++D ++ ++ +  + k   +   + +LvnN+G   + ++pf e+
  EEA21092.1  76 WALITGASDGLGKEFALQIARAGFNVILVSRTESKLVSLADEIKSKnpATQTKILAMDFAQNKDSDYELLKSLINGLDIAILVNNVGKshSIPVPFDET 174
                 69*******************************************999999*********666666444444444457889******998999****** PP

                 SHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHH CS
   adh_short  97 seeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakel 190
                  e+e++++i++N +g++ +t++v+p m+++++G I +++S  g+ p + +a Ys sKa+++ ++++l  el+p+gi+v+ ++  l+ ++m k +
  EEA21092.1 175 PEDEMKDIININCHGTLRVTKLVTPGMIERKRGLILTMGSFGGLLPTPLLATYSGSKAFLQYWSSALGAELEPYGITVQLMQAHLITSAMSKIR 268
                 **************************************************************************************99998755 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.1   0.0   2.4e-25   7.1e-22       1     179 [.      81     265 ..      81     276 .. 0.89

  Alignments for each domain:
  == domain 1  score: 78.1 bits;  conditional E-value: 2.4e-25
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGH.HHHHHHHHHHTTSE...EEE--TTSHHHHH.HHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-H CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneea.kkrveelaeelgae...vlecDVtdeeqve.alveevvekfgklDilvnnagiapklkgpfletsr 92 
                   Ga  g+G++ A ++a++G +v+l+ + e++  + ++e++++ +a+   +l++D +++++ + +l + + + +  + ilvnn+g ++++  pf et++
    EEA21092.1  81 GASDGLGKEFALQIARAGFNVILVSRTESKlVSLADEIKSKNPATqtkILAMDFAQNKDSDyELLKSLINGL-DIAILVNNVGKSHSIPVPFDETPE 176
                   899***************************8899999999888554346****9998887725555555554.7889******************** PP

                   HHHHHHHHHHTHHHHHHHHHHHH.HCTSC.CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGG CS
  adh_short_C2  93 eefdraldvnlyslfllakaalp.lmkeg.gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaa 179
                   +e+++++++n++++++++k + p +++++ g i+++ s+g+   +p  + y+ +Ka l+  + +l +el p+gi+v    + +i   ++
    EEA21092.1 177 DEMKDIININCHGTLRVTKLVTPgMIERKrGLILTMGSFGGLLPTPLLATYSGSKAFLQYWSSALGAELEPYGITVQLMQAHLITSAMS 265
                   ***********************8776667************************************************99999986664 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       1.5   4.6e+03     152     169 ..      11      28 ..       3      41 .. 0.66
   2 !   22.8   0.0   2.4e-08   7.2e-05       3     158 ..      77     236 ..      75     257 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1.5
                 HHHHHHHHHHHHHHHHHT CS
          KR 152 aNaflDalaeyrrsqglp 169
                  N +l+ la+ r++   +
  EEA21092.1  11 LNLYLNKLAHFRAADMSQ 28 
                 588999999999875544 PP

  == domain 2  score: 22.8 bits;  conditional E-value: 2.4e-08
                 EEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHT..T-EEEE----TT-HHH.HHHHHHHHHHHSS---EEEE------..--- CS
          KR   3 ylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaeleal..gaevevvaaDvsdkda.vealleeikaeeppikGvihaAgvlr..dkl 96 
                  litG+  gLG+e+a ++a+ g  +++l+sR+++   +  +l +e++++   ++ +++a+D +++++   +ll+++  ++  i+  ++  g ++    +
  EEA21092.1  77 ALITGASDGLGKEFALQIARAGF-NVILVSRTES---KLVSLADEIKSKnpATQTKILAMDFAQNKDsDYELLKSLI-NGLDIAILVNNVGKSHsiPVP 170
                 69*****************9996.7899****33...333467777776447899******9876550556666665.566899999988877733578 PP

                 TTT--HHHHHHHHTTTTHHHHHHHHHTTT....S--SEEEEEEEHHHHH--TT-HHHHHHHHHHHH CS
          KR  97 leemtaedleqvlapKvkGawnLhelled....esldffvlfSSiagllgsagqanYaaaNaflDa 158
                 ++e+ +++++ +++  ++G+  + +l+++    ++  +++++ S +gll ++  a+Y+   afl  
  EEA21092.1 171 FDETPEDEMKDIININCHGTLRVTKLVTPgmieRKRGLILTMGSFGGLLPTPLLATYSGSKAFLQY 236
                 99***********************9998777788889999*****************99999875 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.0   2.9e-07   0.00085       2     114 ..      78     196 ..      77     204 .. 0.75

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 2.9e-07
                      EEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH......-TTEEEE....E.--TT-HHHHHHHTT..T-SEEEE------...HH CS
  Polysacc_synt_2   2 lvtGagGsiGselvrqilkkkpkkiillerdElklyeiekeleeelkkkklkveivpvi.gdvrdkerlekaleelkvdvvfhaAAlKh...VP 91 
                      l+tGa+  +G+e+  qi++    ++il++r+E kl ++++e++++  ++++k+  + +   +  d e l+++++ l++ ++++     h   VP
       EEA21092.1  78 LITGASDGLGKEFALQIARAGF-NVILVSRTESKLVSLADEIKSKNPATQTKILAMDFAqNKDSDYELLKSLINGLDIAILVNNVGKSHsipVP 170
                      8****************99887.58899*************98888877776654433303345678899999999999888877766654455 PP

                      HH...HHSHHHHHHHHHHHHHHHHHH CS
  Polysacc_synt_2  92 lv...eenpleaiktNvlgtenviea 114
                           e ++ + i+ N +gt  v + 
       EEA21092.1 171 FDetpEDEMKDIININCHGTLRVTKL 196
                      44112557777888899998888765 PP

>> T3SS_needle_reg  YopR, type III needle-polymerisation regulator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   2.1e-05     0.064       7      77 ..     106     173 ..     101     187 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 2.1e-05
                      ........XXXXXXXX-HHHHHHHHHHHHHH...-SS--HHHHHHHHHHHHHHHHHHHTT--S---HHHHH CS
  T3SS_needle_reg   7 skqsvlssLenvlkdedpetqrevlWqayqalkskkpsddavlevLlapvkeeLladfgglqgsvkPplDl 77 
                      + +s l sL + +k+++p+tq ++l   + +   +k sd   l+ L+  +  ++l +  g+  s+  p D 
       EEA21092.1 106 RTESKLVSLADEIKSKNPATQTKILAMDFAQ---NKDSDYELLKSLINGLDIAILVNNVGKSHSIPVPFDE 173
                      5678999************************...9999999******999999998888888888777774 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0    0.0001      0.31      10      50 ..      86     122 ..      77     140 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.0001
                    HHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC-EE CS
  F420_oxidored  10 mgealasgllaagaqpheivvansrnpekaeelaeelgvkv 50 
                    +g+ +a+++++ag    +++++ sr+++k+ +la+e++ k 
     EEA21092.1  86 LGKEFALQIARAG---FNVILV-SRTESKLVSLADEIKSKN 122
                    68999********...****88.*************98433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (350 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       439  (0.0244855); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.40
# Mc/sec: 2644.04
//
Query:       EEA21093.1  [L=516]
Description: succinate semialdehyde dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     4e-148  493.8   0.0   4.5e-148  493.6   0.0    1.0  1  Aldedh    Aldehyde dehydrogenase family


Domain annotation for each model (and alignments):
>> Aldedh  Aldehyde dehydrogenase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  493.6   0.0  2.5e-152  4.5e-148       5     461 ..      41     507 ..      37     508 .. 0.96

  Alignments for each domain:
  == domain 1  score: 493.6 bits;  conditional E-value: 2.5e-152
                 SSSE.EEEEETTTCEEEEEEE-B-HHHHHHHHHHHHHHHHHHTTS-HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH---HHHHHHHHHHHHHHHHHHHH CS
      Aldedh   5 eset.ievinPatgeviakvpaataedvdaavaaAkeafkawaklpaeeRaeiLrkaadlleerkeelaeletletGkplaearaeveeaidvlryyae 102
                  s++ +   +P +g+++a++p++ +edvd++v++A+ af+ ++++++++Ra++L ++++l+ + +++la++++ etGkpl+ea +e+++ +++  ++a+
  EEA21093.1  41 LSGNfFTIEDPGSGTKWATCPDCIPEDVDNVVQKAHVAFQLYSRTNPRKRAQLLSTWHQLILSARDDLAKILVYETGKPLTEAFGEIDYGASFTWWFAG 139
                 553448899****************************************************************************************** PP

                 HHHHHSEEEEEE.CTTEEEEEEEEE-SEEEEEE-SSSCCHHHHHHHHHHHHTT-EEEEEE-TTSHHHHHHHHHHHHHTTS-TTSEEE--SS...TCCHH CS
      Aldedh 103 laeklegevlps.segklalvrrePlGvvgaItPWNfPlllaawklapalaaGNtvvlKPaeetplsalllaelfeeaglPkgvlnvvtgs...gsevg 197
                 +a++++g++l s ++++++++ ++P+Gv +a++PWNfP++l+++k+ +alaaG+t+v+KP++etp++al la l+ +ag+Pkg++nv+t+s      v+
  EEA21093.1 140 EADRIRGSTLVSaADNRRTVTIKQPIGVAAALVPWNFPIALVLRKVSAALAAGCTIVVKPSPETPMTALCLADLATRAGFPKGAFNVLTTSlenTPAVA 238
                 *******88888689*************************************************************************8764447789* PP

                 HHHHH-TTESEEEEES-HHHHHHHHHHHHCTTSEEEEEE---EEEEE-TTSHHHHHHHHHHHHHHGGGGTSTTSEEEEEEEHHHHHHHHHHHHHHHHT- CS
      Aldedh 198 ealvehpevdkvsftGstevgrkiakaaaknlkrvtlElGGknplivledaDldkaveaivkgafgnaGQvCiaasrllvqesiydefveklveaakkl 296
                 + l++hp v+kv+ftGst+vg+ ia+ +a+ lk+ t ElGG+ pli ++daDld a++++ +  +++aGQ C++a+r++v++ iy++f+e++++++k+l
  EEA21093.1 239 QSLCTHPLVKKVTFTGSTRVGKIIARLCADYLKKSTCELGGNCPLICFADADLDLAIDQLFALKWRHAGQACVTANRVYVERAIYQDFIERIIKQTKTL 337
                 *************************************************************************************************** PP

                 -BS-TTSTT-SB---SSHHHHHHHHHHHHHHHHTTSEEEE-TT.....E.SB-SSSTTEE--EEEES-TTTSHHHHS---SSEEEEEEESSHHHHHHHH CS
      Aldedh 297 kvgdpldedtdvGPliseaqlekvekyveeakeegaklllGge.....reeaglekgyfvePtvlanvtpdmriaqeEiFGPVlsvikfkdeeeaieia 390
                  vg++ld++t++GP++ e+ l+++e++v++a+ +gak++lG        + ++l kg+f++Pt+l ++t++m + +eE+FGPVl ++ f++e+e+ + a
  EEA21093.1 338 VVGHGLDPNTTMGPVTVERGLDRLEDLVADAVGKGAKIVLGTGtrchkDNIKDLTKGFFMKPTILVDMTDEMIMTHEEVFGPVLGIYLFETEQEITDRA 436
                 ****************************************876678765667899******************************************** PP

                 HSSSEESEEEEE-SBHHHHHHHHHHS-SSEEEESSSST--TTTSEB--CGGGEES-BSH.HHHHHHTEEEEE CS
      Aldedh 391 NdteyGLaagvftkdleraervaerleaGnvyiNdsttgaaealpfgGvkqSglGregg.kegleeytevkt 461
                 N+t+yGLa++vft++  r+ r++e+leaG++++N  + +aaea pfgG+k+Sg+G+e+g   +++ey+  kt
  EEA21093.1 437 NATPYGLASYVFTENTHRIWRMMENLEAGMIGLNVGNSSAAEA-PFGGMKDSGWGKESGkDVAIDEYLVSKT 507
                 *****************************************99.***************6778999999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (516 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       517  (0.028836); expected 358.6 (0.02)
Passed bias filter:                      478  (0.0266607); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.43
# Mc/sec: 3564.50
//
Query:       EEA21094.1  [L=516]
Description: succinate semialdehyde dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     4e-148  493.8   0.0   4.5e-148  493.6   0.0    1.0  1  Aldedh    Aldehyde dehydrogenase family


Domain annotation for each model (and alignments):
>> Aldedh  Aldehyde dehydrogenase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  493.6   0.0  2.5e-152  4.5e-148       5     461 ..      41     507 ..      37     508 .. 0.96

  Alignments for each domain:
  == domain 1  score: 493.6 bits;  conditional E-value: 2.5e-152
                 SSSE.EEEEETTTCEEEEEEE-B-HHHHHHHHHHHHHHHHHHTTS-HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH---HHHHHHHHHHHHHHHHHHHH CS
      Aldedh   5 eset.ievinPatgeviakvpaataedvdaavaaAkeafkawaklpaeeRaeiLrkaadlleerkeelaeletletGkplaearaeveeaidvlryyae 102
                  s++ +   +P +g+++a++p++ +edvd++v++A+ af+ ++++++++Ra++L ++++l+ + +++la++++ etGkpl+ea +e+++ +++  ++a+
  EEA21094.1  41 LSGNfFTIEDPGSGTKWATCPDCIPEDVDNVVQKAHVAFQLYSRTNPRKRAQLLSTWHQLILSARDDLAKILVYETGKPLTEAFGEIDYGASFTWWFAG 139
                 553448899****************************************************************************************** PP

                 HHHHHSEEEEEE.CTTEEEEEEEEE-SEEEEEE-SSSCCHHHHHHHHHHHHTT-EEEEEE-TTSHHHHHHHHHHHHHTTS-TTSEEE--SS...TCCHH CS
      Aldedh 103 laeklegevlps.segklalvrrePlGvvgaItPWNfPlllaawklapalaaGNtvvlKPaeetplsalllaelfeeaglPkgvlnvvtgs...gsevg 197
                 +a++++g++l s ++++++++ ++P+Gv +a++PWNfP++l+++k+ +alaaG+t+v+KP++etp++al la l+ +ag+Pkg++nv+t+s      v+
  EEA21094.1 140 EADRIRGSTLVSaADNRRTVTIKQPIGVAAALVPWNFPIALVLRKVSAALAAGCTIVVKPSPETPMTALCLADLATRAGFPKGAFNVLTTSlenTPAVA 238
                 *******88888689*************************************************************************8764447789* PP

                 HHHHH-TTESEEEEES-HHHHHHHHHHHHCTTSEEEEEE---EEEEE-TTSHHHHHHHHHHHHHHGGGGTSTTSEEEEEEEHHHHHHHHHHHHHHHHT- CS
      Aldedh 198 ealvehpevdkvsftGstevgrkiakaaaknlkrvtlElGGknplivledaDldkaveaivkgafgnaGQvCiaasrllvqesiydefveklveaakkl 296
                 + l++hp v+kv+ftGst+vg+ ia+ +a+ lk+ t ElGG+ pli ++daDld a++++ +  +++aGQ C++a+r++v++ iy++f+e++++++k+l
  EEA21094.1 239 QSLCTHPLVKKVTFTGSTRVGKIIARLCADYLKKSTCELGGNCPLICFADADLDLAIDQLFALKWRHAGQACVTANRVYVERAIYQDFIERIIKQTKTL 337
                 *************************************************************************************************** PP

                 -BS-TTSTT-SB---SSHHHHHHHHHHHHHHHHTTSEEEE-TT.....E.SB-SSSTTEE--EEEES-TTTSHHHHS---SSEEEEEEESSHHHHHHHH CS
      Aldedh 297 kvgdpldedtdvGPliseaqlekvekyveeakeegaklllGge.....reeaglekgyfvePtvlanvtpdmriaqeEiFGPVlsvikfkdeeeaieia 390
                  vg++ld++t++GP++ e+ l+++e++v++a+ +gak++lG        + ++l kg+f++Pt+l ++t++m + +eE+FGPVl ++ f++e+e+ + a
  EEA21094.1 338 VVGHGLDPNTTMGPVTVERGLDRLEDLVADAVGKGAKIVLGTGtrchkDNIKDLTKGFFMKPTILVDMTDEMIMTHEEVFGPVLGIYLFETEQEITDRA 436
                 ****************************************876678765667899******************************************** PP

                 HSSSEESEEEEE-SBHHHHHHHHHHS-SSEEEESSSST--TTTSEB--CGGGEES-BSH.HHHHHHTEEEEE CS
      Aldedh 391 NdteyGLaagvftkdleraervaerleaGnvyiNdsttgaaealpfgGvkqSglGregg.kegleeytevkt 461
                 N+t+yGLa++vft++  r+ r++e+leaG++++N  + +aaea pfgG+k+Sg+G+e+g   +++ey+  kt
  EEA21094.1 437 NATPYGLASYVFTENTHRIWRMMENLEAGMIGLNVGNSSAAEA-PFGGMKDSGWGKESGkDVAIDEYLVSKT 507
                 *****************************************99.***************6778999999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (516 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       517  (0.028836); expected 358.6 (0.02)
Passed bias filter:                      478  (0.0266607); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 3305.23
//
Query:       EEA21095.1  [L=447]
Description: hypothetical protein PMAA_049000 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      9e-07   28.2   0.0    1.3e-06   27.7   0.0    1.4  1  Fungal_trans  Fungal specific transcription factor domain
    0.00048   20.4   0.1       0.44   10.9   0.0    3.1  3  DUF3143       Protein of unknown function (DUF3143)


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.7   0.0   1.4e-10   1.3e-06     140     248 ..     280     404 ..     187     433 .. 0.76

  Alignments for each domain:
  == domain 1  score: 27.7 bits;  conditional E-value: 1.4e-10
  Fungal_trans 140 s.......lwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddlwesddaseetlvetk..........lsneeksrkias 219
                   +        w +w++ +e+ +R++wa F  D+  a  +Gr    d  +  l++Pc +  lwe+ +a +++ ++            l+  + +r+ ++
    EEA21095.1 280 TnmddvhaEWIQWID-REREKRVTWASFEYDCSRAALTGRRGAVDLGEFPLRFPCAEA-LWEAPSAQAWRSLSLHsysgisvataLERVMAGRLLPN 374
                   144445558******.**************************88**************.*************9555555555555555555555554 PP

  Fungal_trans 220 flla.Lkkilskiagsllsiekqlqqrdlq 248
                   +l++  k++ s+i g lls  kql+  +l+
    EEA21095.1 375 GLSSwGKRLCSQIIGRLLSDIKQLEVAYLS 404
                   444423555555888888888888766655 PP

>> DUF3143  Protein of unknown function (DUF3143)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.9   0.0   4.9e-05      0.44      39      61 ..      92     114 ..      76     118 .. 0.85
   2 !    5.5   0.0    0.0024        22      32      56 ..     289     313 ..     281     317 .. 0.87
   3 ?   -1.1   0.0      0.27   2.5e+03      25      38 ..     392     405 ..     389     419 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 4.9e-05
     DUF3143  39 geggkdiqrsFkYsLsReDieaA 61 
                 +++++di+ s  YsLsR+D+ a 
  EEA21095.1  92 TQSQSDIEESIIYSLSRDDVPAS 114
                 67899**************9776 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.0024
     DUF3143  32 tVrYlkageggkdiqrsFkYsLsRe 56 
                 ++++++++ +++ +  sF+Y +sR+
  EEA21095.1 289 WIQWIDREREKRVTWASFEYDCSRA 313
                 5899999999**************8 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 0.27
     DUF3143  25 lLdieeltVrYlka 38 
                 l di +l V Yl++
  EEA21095.1 392 LSDIKQLEVAYLSK 405
                 55999******875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (447 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       294  (0.016398); expected 358.6 (0.02)
Passed bias filter:                      259  (0.0144459); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.29s 00:00:00.85 Elapsed: 00:00:00.49
# Mc/sec: 2763.44
//
Query:       EEA21096.1  [L=250]
Description: oxidoreductase, short-chain dehydrogenase/reductase family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-58  198.3   0.0    1.6e-58  198.0   0.0    1.0  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    1.2e-45  155.4   0.2    1.6e-45  155.0   0.2    1.1  1  adh_short        short chain dehydrogenase
    1.1e-07   32.0   0.0    1.9e-07   31.2   0.0    1.3  1  KR               KR domain
     0.0002   21.6   0.1    0.00033   20.9   0.1    1.3  1  TrkA_N           TrkA-N domain
    0.00024   20.7   0.1     0.0006   19.3   0.1    1.6  1  Epimerase        NAD dependent epimerase/dehydratase family
  ------ inclusion threshold ------
      0.013   14.7   0.4      0.023   13.9   0.4    1.4  1  Polysacc_synt_2  Polysaccharide biosynthesis protein
      0.026   14.4   0.1      0.038   13.9   0.1    1.3  1  3HCDH_N          3-hydroxyacyl-CoA dehydrogenase, NAD binding
       0.11   12.5   0.1       0.19   11.7   0.1    1.4  1  ADH_zinc_N       Zinc-binding dehydrogenase


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  198.0   0.0   7.3e-62   1.6e-58       1     232 [.      14     247 ..      14     248 .. 0.95

  Alignments for each domain:
  == domain 1  score: 198.0 bits;  conditional E-value: 7.3e-62
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSEEEE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHHH CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneeakkrveelaeelgaevlecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreefdr 97 
                   Gaasg G++iA ++ eeGa+v+++dl+ee+    +++a+el+ e++  DVt++++++++ ++  e fg+lDi+vnnag + + ++p++++++++fd 
    EEA21096.1  14 GAASGFGKGIATKFVEEGAKVLIVDLSEES---GQKVAKELSCEFVVGDVTKRTHWQEILRKSLEIFGGLDIVVNNAGATYA-NKPTTSVTDADFDL 106
                   9****************************9...89**********************************************9.************** PP

                   HHHHHTHHHHHHHHHHHHHCTSC...CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTT...HHHH CS
  adh_short_C2  98 aldvnlyslfllakaalplmkeg...gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikg...fdel 188
                   +++vn++s++l +  ++p++ ++   g  + +ss++a r  p+ ++y+a+K+a+   ++++A+e+g++++R N+v+p +  T ++  + g   ++e 
    EEA21096.1 107 VMNVNVKSIYLSTDVIVPYFLDNnrpGVFIQISSTAAIRPRPGLTWYNASKGAVSIASKSMAAEFGSRQVRFNTVCPVVGSTGMTHLFLGkpdTEEN 203
                   ******************55444479**********************************************************8766553337889 PP

                   HHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEESTT CS
  adh_short_C2 189 leelearaplgrlgtpeevaeaalfLasdeasyitGqtlvvDgG 232
                   ++++ + +pl+r  tp +va+a+++Lasdea++itG +l vDgG
    EEA21096.1 204 RAAFVETIPLRRPSTPADVANACCYLASDEAAFITGVDLEVDGG 247
                   9999***************************************9 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  155.0   0.2   7.1e-49   1.6e-45       1     188 [.       8     192 ..       8     196 .. 0.98

  Alignments for each domain:
  == domain 1  score: 155.0 bits;  conditional E-value: 7.1e-49
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---S.S--SSGGGCSH CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGi.tgsgpfselse 98 
                 kv+++tGa+sG+G+ ia ++++eGakv++vd see  ++vakel        ++ +Dvt+r+ ++++++k  + +g+ld++vnNAG    ++p+ ++++
  EEA21096.1   8 KVAIITGAASGFGKGIATKFVEEGAKVLIVDLSEESGQKVAKELS-----CEFVVGDVTKRTHWQEILRKSLEIFGGLDIVVNNAGAtYANKPTTSVTD 101
                 89******************************************9.....68***********************************8899******** PP

                 HHHHHHHHHHTHHHHHHHHHHHHHHH.HCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHH CS
   adh_short  99 eewervievNltgvflltravlpaml.kqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmak 188
                 ++++ v++vN+++++l t  ++p++l +++ G  +++sS+a+  p +g++ Y AsK+av   ++s+a e+ ++++r n+v+P + +T+m++
  EEA21096.1 102 ADFDLVMNVNVKSIYLSTDVIVPYFLdNNRPGVFIQISSTAAIRPRPGLTWYNASKGAVSIASKSMAAEFGSRQVRFNTVCPVVGSTGMTH 192
                 ************************8879999*****************************************************99*9985 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.2   0.0   8.6e-11   1.9e-07       4     152 ..      11     156 ..       9     169 .. 0.83

  Alignments for each domain:
  == domain 1  score: 31.2 bits;  conditional E-value: 8.6e-11
                 EEETTTSHHHHHHHHHHHHHHS-EEEE.E-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE-----.----TTT- CS
          KR   4 litGGlGgLGlelarwlaekgarhlvl.lsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvl.rdklleem 100
                 +itG++ g+G+ +a+  +e+ga+ l++ ls +     + ++  +     + ++e+v  Dv+++++ +++l++  + ++ +  v++ Ag++ ++k+ +++
  EEA21096.1  11 IITGAASGFGKGIATKFVEEGAKVLIVdLSEE-----SGQKVAK-----ELSCEFVVGDVTKRTHWQEILRKSLEIFGGLDIVVNNAGATyANKPTTSV 99 
                 8**********************999823433.....2232333.....45679999******************************97626999**** PP

                 -HHHHHHHHTTTTHHHHHHHHHTTT.....S--SEEEEEEEHHHHH--TT-HHHHHH CS
          KR 101 taedleqvlapKvkGawnLhelled.....esldffvlfSSiagllgsagqanYaaa 152
                 t++d++ v++  vk +     ++ +     ++  +f+ +SS a++   +g + Y a 
  EEA21096.1 100 TDADFDLVMNVNVKSIYLSTDVIVPyfldnNRPGVFIQISSTAAIRPRPGLTWYNAS 156
                 *************9876655554442333478889***********99999999986 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.1   1.5e-07   0.00033       6      58 ..      16      69 ..      10      77 .. 0.86

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 1.5e-07
                -SHHHHHHHHHHHHTTEEEEEEESSHHHHHHHHHTT.SEEEES-TTSHHHHHHT CS
      TrkA_N  6 lGrvGrslaeeLseggkdvvvidkdeerveelreeg.levvvgdatdeevLeea 58
                ++ +G+ +a ++ e+g +v+++d +ee  +++++e  +e+vvgd+t++  ++e+
  EEA21096.1 16 ASGFGKGIATKFVEEGAKVLIVDLSEESGQKVAKELsCEFVVGDVTKRTHWQEI 69
                5679**********6657***************9999**********9999886 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.1   2.7e-07    0.0006       2     161 ..      11     172 ..      10     192 .. 0.63

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 2.7e-07
                 EEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC..EEEE--TT-HHHHHHHHHH....H.T-SEEEE--S---HHHHHHSHHHHHHHHTH CS
   Epimerase   2 lVtGatGfiGsalvkallekgyevigldrlssasntarledl..elveldltdrsalerlfke....e.qpdavihlAavggvaassedpadfieknlq 93 
                 ++tGa+   G+ ++ ++ e+g +v+ +d  ++++++ ++e l  e+v +d+t+r+ +++++++    + + d+v++             +++  + ++ 
  EEA21096.1  11 IITGAASGFGKGIATKFVEEGAKVLIVDLSEESGQKVAKE-LscEFVVGDVTKRTHWQEILRKsleiFgGLDIVVNN----------AGATYANKPTTS 98 
                 89*************************9996666655544.358***********8888887511112334555554..........444444444444 PP

                 HHHHHHHHHHHHTCTEEEEEEEGGGGT...SCSSSS....BSTCSTTS--.--SSHHHHHHHHHHHHHHHHHHHHT CS
   Epimerase  94 gtlnlleaarkagvkrllflsSsevYG...kdaeqp....keettltgpl.kpnspYaaaKlageklveayaaqyg 161
                 +t   ++ +   +v + ++ls++ + +   +++  p    + ++t      +  + Y a+K a+    +++aa++g
  EEA21096.1  99 VTDADFDLVMNVNV-KSIYLSTDVIVPyflDNN-RPgvfiQISSTAAIRPrPGLTWYNASKGAVSIASKSMAAEFG 172
                 44444555555566.666666666666443111.234434333333333335566677777777666666666666 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.4     1e-05     0.023       2     135 ..      11     147 ..      10     194 .. 0.56

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1e-05
                      EEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH......-TTEEEE....E--TT-HHHHHHHTT.......T-SEEEE--....- CS
  Polysacc_synt_2   2 lvtGagGsiGselvrqilkkkpkkiillerdElklyeiekeleeelkkkklkveivpvigdvrdkerlekaleel.....kvdvvfhaA....A 86 
                      ++tGa+  +G+ + ++++++ + k+++++ +E + ++++kel+          e   v+gdv+++++ +++l++      + d+v++ A    A
       EEA21096.1  11 IITGAASGFGKGIATKFVEEGA-KVLIVDLSEESGQKVAKELS-------C--E--FVVGDVTKRTHWQEILRKSleifgGLDIVVNNAgatyA 92 
                      69****************9876.678899***99999999983.......2..2..46999999998888887532223356777665433222 PP

                      ---HHHHHHSHHH.HHHHHH....HHHHHHHHHHHH.TT-SEEEEEEEGGGSS-- CS
  Polysacc_synt_2  87 lKhVPlveenple.aiktNv....lgtenvieaaie.agvkkvvliStDKAvnPt 135
                       K    v    ++ +++ Nv    l+t+ ++   ++ ++   ++ iS+  A++P 
       EEA21096.1  93 NKPTTSVTDADFDlVMNVNVksiyLSTDVIVPYFLDnNRPGVFIQISSTAAIRPR 147
                      3333333333333133445522222344444333330333456667777777664 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.1   1.7e-05     0.038      10      44 ..      19      53 ..       8      76 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.7e-05
                CHHHHHHHHHHTT-EEEEE-S-HHHHHHHHHHHHH CS
     3HCDH_N 10 mGagiaavfasagleVvlvdiseealekalekiek 44
                 G+gia+ f+++g +V +vd see+ +k++++++ 
  EEA21096.1 19 FGKGIATKFVEEGAKVLIVDLSEESGQKVAKELSC 53
                7************************9999998765 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.1   8.3e-05      0.19      14      69 ..      31      90 ..      28     108 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 8.3e-05
                T-EEEEEESSHHHH.HHHHHTTESEEEET..TTCHHHHHHHHHTT.TSSEEEEEESSCSH CS
  ADH_zinc_N 14 Gaeviavdsseekl.elakklGadeviny..keadlverikeltg.gegvdvvfecvGsg 69
                Ga+v  vd see   + ak+l +++v+    k+++++e +++  +  +g+d+v++ +G+ 
  EEA21096.1 31 GAKVLIVDLSEESGqKVAKELSCEFVVGDvtKRTHWQEILRKSLEiFGGLDIVVNNAGAT 90
                99*********987255666*******999666599999999887766*********943 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (250 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       438  (0.0244297); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 1785.52
//
Query:       EEA21097.1  [L=158]
Description: 3-isopropylmalate dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-25   90.1   0.0    1.7e-25   89.9   0.0    1.0  1  Iso_dh    Isocitrate/isopropylmalate dehydrogenase


Domain annotation for each model (and alignments):
>> Iso_dh  Isocitrate/isopropylmalate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.9   0.0   9.4e-30   1.7e-25       2     123 ..       7     134 ..       6     155 .. 0.91

  Alignments for each domain:
  == domain 1  score: 89.9 bits;  conditional E-value: 9.4e-30
                 EEEEEESTTHHHHHHHHHHHHHHHHHHHT.-EEEEEE---THHHHHHHSSSS-HHHHHHHHHSSEEEEEE---CS....SSSSSHHHHHHHHHHHTTEE CS
      Iso_dh   2 iallegdgiGpevveaalkvlkaakekag.lelefeevdvGgaaidetgeplpeetleaikeadvvllgavgtpk....ekevrpengLlaLrkeldlf 95 
                 + +l gd iGpe++++alk l+ ++e+++  ++++ +  ++ga++d+t+ep++++ l+a+ ++d+vllg+vg p+    ++ ++pe+g+l+Lr+ ld f
  EEA21097.1   7 LLVLRGDRIGPEIIAEALKPLTVLVEERPdFKVQVRYGLLAGASLDKTNEPITDKVLDAALATDAVLLGSVGEPEwahmPGALNPEKGILRLRQRLDAF 105
                 6799******************988776669***********************************************999****************** PP

                 EEEEEEE-B.CCTTCCSSBTHHHHCT-EE CS
      Iso_dh  96 anlrpvkvf.eklkvksplkrevveevdl 123
                 an+rp+++   +l+++splk+++v++v++
  EEA21097.1 106 ANIRPCRFCaSSLVEQSPLKSDMVNGVNF 134
                 ********9999********988888654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (158 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       285  (0.015896); expected 358.6 (0.02)
Passed bias filter:                      253  (0.0141112); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.23s 00:00:00.62 Elapsed: 00:00:00.39
# Mc/sec: 1213.24
//
Query:       EEA21098.1  [L=664]
Description: hypothetical protein PMAA_049030 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.2e-05   23.2   0.0    0.00024   21.4   0.0    2.0  1  Ank_5     Ankyrin repeats (many copies)
  ------ inclusion threshold ------
      0.037   14.5   0.1          2    9.0   0.1    2.5  2  Ank       Ankyrin repeat
      0.062   13.9   0.0       0.15   12.7   0.0    1.6  1  Ank_2     Ankyrin repeats (3 copies)


Domain annotation for each model (and alignments):
>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0   3.9e-08   0.00024       1      43 [.       5      44 ..       5      50 .. 0.90

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 3.9e-08
       Ank_5  1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadln 43
                Lle+g advn + ++g+t L++A  +g  dvv++Ll  +a ++
  EEA21098.1  5 LLERG-ADVNIPGNYGVTTLMLALQRGLHDVVEKLL--QAGAT 44
                89***.******************************..55555 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.0      0.03   1.8e+02      18      30 ..       2      15 ..       1      17 [. 0.83
   2 ?    9.0   0.1   0.00033         2       1      26 [.      18      44 ..      18      46 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.03
                HHHHH.TTTSTTCB CS
         Ank 18 iklLL.hGAnlnal 30
                i  LL +GA++n+ 
  EEA21098.1  2 ITVLLeRGADVNIP 15
                889**88*****86 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00033
                TSBBHHHHHHHHTTHHHHHHHH.TTTS CS
         Ank  1 dGnTPLHlAatngkkriiklLL.hGAn 26
                +G T L+lA ++g +++++ LL  GA 
  EEA21098.1 18 YGVTTLMLALQRGLHDVVEKLLqAGAT 44
                69999*****************66986 PP

>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   2.5e-05      0.15      43      77 ..       3      43 ..       1      55 [. 0.64

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.5e-05
       Ank_2 43 klLleh...ad...ndgrtpLhyAarsghleivklLlekga 77
                  Lle    ++   n+g t L++A + g  ++v+ Ll+ ga
  EEA21098.1  3 TVLLERgadVNipgNYGVTTLMLALQRGLHDVVEKLLQAGA 43
                45666453333555777777777777776677777776565 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (664 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       522  (0.0291148); expected 358.6 (0.02)
Passed bias filter:                      499  (0.027832); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.25s 00:00:00.87 Elapsed: 00:00:00.42
# Mc/sec: 4762.98
//
Query:       EEA21099.1  [L=547]
Description: MFS monosaccharide transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   5.6e-135  450.7  30.8   6.4e-135  450.5  30.8    1.0  1  Sugar_tr  Sugar (and other) transporter
    3.2e-25   88.8  50.5    2.7e-20   72.6  31.8    2.2  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.025   14.8   2.2      0.025   14.8   2.2    4.5  6  DUF2530   Protein of unknown function (DUF2530)


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  450.5  30.8  1.1e-138  6.4e-135       3     452 .]      59     513 ..      57     513 .. 0.95

  Alignments for each domain:
  == domain 1  score: 450.5 bits;  conditional E-value: 1.1e-138
                 HHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS CS
    Sugar_tr   3 lvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgkns 101
                 l+a++gg++fgY tg i++f t+ +f+ +f +  +++ +  s+v+sgliv+++++G +iG+l a++l+drfGRk s+ + +++ ++g+++q+a+   ++
  EEA21099.1  59 LIASMGGFIFGYSTGQISGFETMHDFQVRFAQHDESGYYF-SNVRSGLIVGLMSIGTMIGALAASPLADRFGRKLSITFWCIIHMVGIIVQIATS--TK 154
                 79****************************9999998555.8****************************************************9..68 PP

                 -TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHH CS
    Sugar_tr 102 vevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPrylve 200
                 +++++vgR+++G+gvG+ s lvPmy+sE Ap ++Rga+vs +ql+++fGi+vaa++++g+++++++  wri++g+ ++++l+l i++lflPESPr+ + 
  EEA21099.1 155 WYQVAVGRLVAGLGVGALSSLVPMYQSESAPRHVRGAMVSAFQLFVAFGIFVAACINFGTERIQSTAAWRITMGIGFAWPLILGIGILFLPESPRFAYR 253
                 *************************************************************************************************** PP

                 TT-HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH.........HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THHHHHHHH CS
    Sugar_tr 201 kgkeeeakevlaklrgeedadrelaeekdsleaeqeee....kaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsksllvtii 295
                  g+ eeak ++ kl g++ ++r +aee++ ++ + +ee    ka + e+++   +++r+l+g++lq++qqltG n+i+yy+ tif ++gl++s+++ +i
  EEA21099.1 254 MGRIEEAKHTMTKLYGVPHNHRLVAEEIADMKDKLDEEkaagKAGVFEIFTGPRMLYRTLLGIGLQSLQQLTGANFIFYYGNTIFTSTGLNNSYVTQMI 352
                 *************99996666666666666666555555556999999999999********************************************* PP

                 HHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH...HHHHTTSS.......CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHH CS
    Sugar_tr 296 vgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilg.ivalllvaks....kaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskala 389
                 +  vnf +t++++++v++fGRR+ l+ Ga+ m++cf+i++    + l  ++      a+  +ivf+++fi+ fa++wgp++w +v El+p + R++++ 
  EEA21099.1 353 MTGVNFGVTIIGLYIVEHFGRRKSLIAGALWMFVCFMIFAtVGHYSLDRADppatPKAGTTLIVFTCFFIVGFATTWGPIVWAIVGELYPARYRATCMG 451
                 ****************************************655555555559999999***************************************** PP

                 HHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 390 iavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 ia+a+nw++nflis+++p+i +ai  + +++vfa++  +++++v+ffv+et grtleei++++
  EEA21099.1 452 IATASNWTWNFLISFFTPFISSAID-FQYGYVFASCSFAAAVVVYFFVCETQGRTLEEIDTMY 513
                 *************************.**********************************996 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.6  31.8   4.6e-24   2.7e-20      28     345 ..      85     457 ..      53     465 .. 0.71
   2 !   30.4  10.7     3e-11   1.8e-07      55     194 ..     367     523 ..     366     546 .. 0.68

  Alignments for each domain:
  == domain 1  score: 72.6 bits;  conditional E-value: 4.6e-24
       MFS_1  28 g............ispseigllltlyalgaavaslplGrlsdrfGrrr.vlllglllfalg.lllllfasslw.lllvlrvlqGlgagalfpagaalia 111
                 +            +s    gl+++l ++g+++++l +++l+drfGr+  + +++++ ++   + +++  s+ w  ++v+r+++Glg gal +++  + +
  EEA21099.1  85 QvrfaqhdesgyyFSNVRSGLIVGLMSIGTMIGALAASPLADRFGRKLsITFWCIIHMVGIiVQIAT--STKWyQVAVGRLVAGLGVGALSSLVPMYQS 181
                 3444444444444666679*****************************6555555555555233333..66666************************* PP

       MFS_1 112 dwfpkeergraigllsagfslGailgpllggllasslg....Wravfyilaivsllafvlfllllpeepperkrkspkeee.................. 188
                 + +p+  rg +++ +++++++G+ +++ +  + ++ +     Wr ++ i  +  l++++ ++l+lpe+p+   r   +ee                   
  EEA21099.1 182 ESAPRHVRGAMVSAFQLFVAFGIFVAACI-NFGTERIQstaaWRITMGIGFAWPLILGI-GILFLPESPRFAYRMGRIEEAkhtmtklygvphnhrlva 278
                 ***********************999555.66666666555677777777777777766.77***9999999999999998999999999999988888 PP

       MFS_1 189 ..........kgtgpaplvp.awkallkdpvlwillialllfffgfsg.........lltllplylqevlglsglllaglllallalvgailallagrl 267
                              +++++ + +  ++++ p +  l  +ll++  g+++         ++++  ++  +  gl+    ++++ +++  v++++ +++ ++
  EEA21099.1 279 eeiadmkdklD--EEKAAGKaGVFEIFTGPRM--LYRTLLGI--GLQSlqqltganfIFYYGNTI-FTSTGLN---NSYVTQMIMTGVNFGVTIIGLYI 367
                 88888887441..3333333534446666655..33333333..333312232222266666654.5555555...44444888888888889999*** PP

       MFS_1 268 sdrlgrrrrlllallllllaalglallavt.............ssavllllvlvliGfglgfv.fpsllalasdlappeeagtasglfntag 345
                 + ++grr+ l+ + l ++++++++a ++++              +++++   ++++  g++++  p+++a++ +l+p+++++t +g+++  +
  EEA21099.1 368 VEHFGRRKSLIAGALWMFVCFMIFATVGHYsldradppatpkaGTTLIVFTCFFIV--GFATTwGPIVWAIVGELYPARYRATCMGIATASN 457
                 **************************************985432222222233333..4444459**********************98655 PP

  == domain 2  score: 30.4 bits;  conditional E-value: 3e-11
       MFS_1  55 lsdrfGrrrvlllglllfalglllll.f.......a.......sslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailg 137
                 +++ fGrr+ l++g+l++++++++++ +       a       ++ + +++ + ++ G+++ +  p++ a++ +++p + r+  +g+++a++     l 
  EEA21099.1 367 IVEHFGRRKSLIAGALWMFVCFMIFAtVghysldrAdppatpkAGTTlIVFTCFFIVGFAT-TWGPIVWAIVGELYPARYRATCMGIATASNWTWNFLI 464
                 6789*****************4444443444444414444556557768999999999996.8888999*********************999999999 PP

       MFS_1 138 pllggllasslgWravfyilaivsllafvlfllll..................peepperkrkspkeeekgtgpa 194
                   + ++++s++ +++ ++++   ++ a v++++++                  +               k ++ +
  EEA21099.1 465 SFFTPFISSAIDFQYGYVFASCSFAAA-VVVYFFVcetqgrtleeidtmyvqhV---------------KPWKSS 523
                 999999999999998866655555555.54455554444443333333333330...............333333 PP

>> DUF2530  Protein of unknown function (DUF2530)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0      0.93   5.5e+03      47      59 ..     103     115 ..      88     127 .. 0.71
   2 ?   14.8   2.2   4.1e-06     0.025      19      73 ..     136     191 ..     129     193 .. 0.85
   3 ?   -1.3   0.2      0.44   2.7e+03      24      59 ..     205     242 ..     197     255 .. 0.55
   4 ?   -2.3   0.2       0.9   5.4e+03      46      60 ..     353     367 ..     331     395 .. 0.62
   5 ?   -0.4   0.2      0.23   1.4e+03       8      32 ..     405     429 ..     403     454 .. 0.73
   6 ?   -0.5   0.0      0.25   1.5e+03      20      38 ..     484     502 ..     475     507 .. 0.76

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.93
     DUF2530  47 aGlvvGllGlaif 59 
                  Gl+vGl+ ++ +
  EEA21099.1 103 SGLIVGLMSIGTM 115
                 5777777766554 PP

  == domain 2  score: 14.8 bits;  conditional E-value: 4.1e-06
     DUF2530  19 vgtllWlvalvvllvvgdal.eswlpvclaGlvvGllGlaiflwQRrAaRrGsrgA 73 
                   +++ +v+++v +++  ++ + ++   +aGl+vG+l   + + Q ++a r  rgA
  EEA21099.1 136 FWCIIHMVGIIVQIATSTKWyQVAVGRLVAGLGVGALSSLVPMYQSESAPRHVRGA 191
                 56789999*99998876666155888999********************9999998 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.44
     DUF2530  24 Wlvalvvllvv.gdaleswlpvclaGlvvG.llGlaif 59 
                 +++a + + +  ++++++w+ +  +G++   +lG++i+
  EEA21099.1 205 FVAACINFGTErIQSTAAWRITMGIGFAWPlILGIGIL 242
                 33343333322023334466666666655423566665 PP

  == domain 4  score: -2.3 bits;  conditional E-value: 0.9
     DUF2530  46 laGlvvGllGlaifl 60 
                 ++G+  G+  +++++
  EEA21099.1 353 MTGVNFGVTIIGLYI 367
                 445544444333333 PP

  == domain 5  score: -0.4 bits;  conditional E-value: 0.23
     DUF2530   8 rrLtdprpvivvgtllWlvalvvll 32 
                 +++ +    ++v t+ ++v++  ++
  EEA21099.1 405 PATPKAGTTLIVFTCFFIVGFATTW 429
                 5566667778899999999988775 PP

  == domain 6  score: -0.5 bits;  conditional E-value: 0.25
     DUF2530  20 gtllWlvalvvllvvgdal 38 
                  ++ +++a+vv ++v ++ 
  EEA21099.1 484 ASCSFAAAVVVYFFVCETQ 502
                 5678999999999886654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (547 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       675  (0.0376485); expected 358.6 (0.02)
Passed bias filter:                      314  (0.0175135); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.61u 0.32s 00:00:00.93 Elapsed: 00:00:00.50
# Mc/sec: 3261.98
//
Query:       EEA21100.1  [L=56]
Description: hypothetical protein PMAA_049050 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (56 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       142  (0.00792013); expected 358.6 (0.02)
Passed bias filter:                       97  (0.00541023); expected 358.6 (0.02)
Passed Vit filter:                         4  (0.000223102); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.35u 0.25s 00:00:00.60 Elapsed: 00:00:00.40
# Mc/sec: 417.40
//
Query:       EEA21101.1  [L=111]
Description: hypothetical protein PMAA_049060 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (111 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       241  (0.0134419); expected 358.6 (0.02)
Passed bias filter:                      215  (0.0119917); expected 358.6 (0.02)
Passed Vit filter:                         7  (0.000390429); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.35u 0.23s 00:00:00.57 Elapsed: 00:00:00.37
# Mc/sec: 896.87
//
Query:       EEA21102.1  [L=660]
Description: nucleolar GTP-binding protein (Nog1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.7e-48  164.6   0.1    1.7e-48  164.6   0.1    2.5  3  NOG1_N       NOG1 N-terminal helical domain
    3.6e-30  103.7   4.2    7.7e-30  102.7   4.2    1.6  1  NOGCT        NOGCT (NUC087) domain
    3.2e-26   90.9   0.4    6.9e-26   89.8   0.4    1.6  1  NOG1         Nucleolar GTP-binding protein 1 (NOG1)
    4.8e-16   58.9   0.0    1.1e-15   57.7   0.0    1.6  1  MMR_HSR1     50S ribosome-binding GTPase
    1.9e-07   30.8   0.1    5.9e-07   29.1   0.1    1.8  1  FeoB_N       Ferrous iron transport protein B
     0.0028   17.7   0.0          2    8.4   0.0    2.8  2  Dynamin_N    Dynamin family
     0.0064   16.9   0.3        0.2   12.1   0.0    3.1  3  AAA_16       AAA ATPase domain
      0.008   16.1   1.1        3.1    7.7   0.1    3.4  3  RsgA_GTPase  RsgA GTPase
  ------ inclusion threshold ------
       0.59   10.6   4.3        1.4    9.3   0.0    2.7  2  AAA_23       AAA domain


Domain annotation for each model (and alignments):
>> NOG1_N  NOG1 N-terminal helical domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  164.6   0.1   8.4e-52   1.7e-48       2     160 .]       6     164 ..       5     164 .. 0.99
   2 ?   -2.2   0.0       1.7   3.5e+03       8      86 ..     300     314 ..     295     349 .. 0.66
   3 ?   -2.8   0.4       2.8   5.5e+03      34      46 ..     614     626 ..     583     643 .. 0.54

  Alignments for each domain:
  == domain 1  score: 164.6 bits;  conditional E-value: 8.4e-52
      NOG1_N   2 ekiptvptseelidkalrrakraakttkkkkneikrlrnlearkvrtasntlsdkLeeivkkfPnldelhpFyrelldvlvdkdelkksLaqvkwarkl 100
                 ++i  vpt +e++d  l+r++r  +t+ +++ +i+r+r +++rkv+++s+t+ +k+++i++ fP+l+++hpF+++l+++l+d d+++++L+q+++a++l
  EEA21102.1   6 KEIAPVPTQQEFLDIVLSRTQRRLPTVIRAGFQISRIRAFYTRKVKFTSETFCEKFQAILDGFPRLQDIHPFHKDLMNTLYDADHFRIALGQISTAKHL 104
                 78999********************************************************************************************** PP

      NOG1_N 101 irkigkeyvnklkkaddkkeakelrreafgrvasvlkkvdkaldfLedvrkkLrkLpaiD 160
                 i++++++yv+++k+a+++ ++k+l+r+a+gr+a++ ++ ++ l +Le+vr++L +Lp+iD
  EEA21102.1 105 IETVARDYVRLIKYAQSLFQCKQLKRAALGRMATICRRLKDPLLYLEQVRQHLGRLPSID 164
                 ***********************************************************9 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.7
      NOG1_N   8 ptseelidkalrrakraakttkkkkneikrlrnlearkvrtasntlsdkLeeivkkfPnldelhpFyrelldvlvdkde 86 
                 p+ +el+d++l++                                                                ++
  EEA21102.1 300 PETKELLDSMLNQ----------------------------------------------------------------SN 314
                 4455555555554................................................................44 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 2.8
      NOG1_N  34 eikrlrnlearkv 46 
                 +++rl +l ++k+
  EEA21102.1 614 KAERLTKLGQKKM 626
                 2222222222222 PP

>> NOGCT  NOGCT (NUC087) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.7   4.2   3.9e-33   7.7e-30       1      54 []     401     454 ..     401     454 .. 0.99

  Alignments for each domain:
  == domain 1  score: 102.7 bits;  conditional E-value: 3.9e-33
       NOGCT   1 rklerdleeenggagvYsvdlkkkYllkndewkyDiiPEildGkNvaDFidpdI 54 
                 rklerd+eeenggagvYsvdl+k+Y+l+ndewkyD+iPEi++GkN++D++dpdI
  EEA21102.1 401 RKLERDIEEENGGAGVYSVDLQKNYTLANDEWKYDKIPEIWNGKNIYDYVDPDI 454
                 89***************************************************9 PP

>> NOG1  Nucleolar GTP-binding protein 1 (NOG1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.8   0.4   3.4e-29   6.9e-26       1      58 []     234     291 ..     234     291 .. 0.99

  Alignments for each domain:
  == domain 1  score: 89.8 bits;  conditional E-value: 3.4e-29
        NOG1   1 eIEkqAiaALkhladavlFllDpseecgysleeQlsLleeikelfankpvivvlnKiD 58 
                 +IE+q+i+A++hl++a+l+++D+se+cgys+ +Q++L+++ik+lfank v+vv+nKiD
  EEA21102.1 234 TIEMQSITAIAHLRSAILYFMDLSEQCGYSVVDQVKLFNSIKPLFANKLVFVVVNKID 291
                 6********************************************************9 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.7   0.0   5.4e-19   1.1e-15       3     114 .]     171     289 ..     169     289 .. 0.71

  Alignments for each domain:
  == domain 1  score: 57.7 bits;  conditional E-value: 5.4e-19
                 EEEESTTSSHHHHHHHHHTSTEEESSSTTSSSSEEEEEEEETTEEEEEEECGGCSS....HHHHHHHHHHHHHHHHCTSEEEEEEETTTT.CSHHHHHH CS
    MMR_HSR1   3 aivGrpNvGKStLinaltgekaivsdkpgtTrdinegrvklkgkeielvDtpGlie....gaseekglgkaflaleeadlillvvdasee.klkpldee 96 
                 +i G+pNvGKS++++++t++ + v+ +++tT+    g++++k  +++ +DtpG+++    + ++ ++ + +  a+ + ++il+ +d+se+ +++ +d +
  EEA21102.1 171 LICGYPNVGKSSFLRSITRADVDVQPYAFTTKSLFVGHFDYKYLRFQAIDTPGILDhpleEMNTIEMQSITAIAHLR-SAILYFMDLSEQcGYSVVD-Q 267
                 799*************************************999**********874232122222233333333555.89******99334565553.2 PP

                 HHHHHHH....TTSEEEEEEES CS
    MMR_HSR1  97 leellee....akkplilvlnk 114
                 ++ +++     a+k +++v+nk
  EEA21102.1 268 VKLFNSIkplfANKLVFVVVNK 289
                 2222211246677778888887 PP

>> FeoB_N  Ferrous iron transport protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.1   0.1     3e-10   5.9e-07       3     155 ..     170     334 ..     168     335 .. 0.70

  Alignments for each domain:
  == domain 1  score: 29.1 bits;  conditional E-value: 3e-10
                 EEEEESTTSSHHHHHHHHHTTSEEEEESTTSSSEEEEEEEEETTEEEEEEE----..SSSSSSSHHHHHHHHHHHCTSSSEEEEEEEGG.....GHHHH CS
      FeoB_N   3 valvGnpnvGkttlfnaltgakqkvgNwpGvtvekkegklklkgkeveivDlPGi..Yslsayseeekvardflleeepdvvvnvvdat.....nlern 94 
                 + ++G pnvGk++++ ++t a+ +v  ++ +t     g++++k  +++ +D PGi  + l+++++ e  + + +++ +  +++  +d +     ++  +
  EEA21102.1 170 LLICGYPNVGKSSFLRSITRADVDVQPYAFTTKSLFVGHFDYKYLRFQAIDTPGIldHPLEEMNTIEMQSITAIAHLR-SAILYFMDLSeqcgySVVDQ 267
                 6789***************************************************44446665555544444444333.34444444321111123334 PP

                 HHHH..HHHHHTTSSEEEEEETHHHHHHTTEEE-HHHH.HHHH...TS-EEEEBTTTTBTHHHHHHH CS
      FeoB_N  95 LyLt..lqllelgvpvvlalnmideaekkgieidlkkL.sekL...gvpvvktsakkkegieellka 155
                 + L+  ++ l  ++ v +++n+id+ + + ++ ++k+L +++L   +v+++++s +++eg+ ++++a
  EEA21102.1 268 VKLFnsIKPLFANKLVFVVVNKIDVKRPEDLDPETKELlDSMLnqsNVEMLQLSCTTTEGVTNVKNA 334
                 4444004444557778899999999999999999887614455333588888999999999988875 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.3   0.0    0.0045         9       2      32 ..     171     201 ..     170     208 .. 0.79
   2 !    8.4   0.0     0.001         2     106     167 ..     219     289 ..     206     290 .. 0.81

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0045
                 EEEEBTTTTHHHHHHHHHTS--S---SSS-- CS
   Dynamin_N   2 avvGsqSsGKSSvlnaLlgedilprgpnptT 32 
                 +++G  + GKSS+l +++++d+ +     tT
  EEA21102.1 171 LICGYPNVGKSSFLRSITRADVDVQPYAFTT 201
                 6899999***********9998665555555 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.001
                 EE---B-SSSGTTS.....HHHHHHHSTTEEEEEEEETTS-CCC-..CHHHHHHHHSTTBTT..EEEEEE- CS
   Dynamin_N 106 vDlPGldsvnkrdq.....elvkeyikkadiilavtsanhdlsns..ealflarevdpkgkr..tivvltk 167
                 +D+PG+ + + +++     + ++ +++ +++il+ ++ + ++  s  ++ +l ++++p   +  ++vv++k
  EEA21102.1 219 IDTPGILDHPLEEMntiemQSITAIAHLRSAILYFMDLSEQCGYSvvDQVKLFNSIKPLFANklVFVVVNK 289
                 9*******999999778766666667**********99987644433999999999999888778888887 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.1   0.0   9.8e-05       0.2       9      47 ..     150     190 ..     148     221 .. 0.86
   2 ?   -1.7   0.2       1.6   3.2e+03     106     107 ..     547     570 ..     458     617 .. 0.56
   3 ?    0.8   0.0      0.28   5.5e+02      28      38 ..     647     657 ..     628     658 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 9.8e-05
      AAA_16   9 leqLlsalervrsgrp..elvllsGesGvGKsslvrellra 47 
                 leq+++ l+r+ s +p  + +l+ G++ vGKss +r++ ra
  EEA21102.1 150 LEQVRQHLGRLPSIDPntRTLLICGYPNVGKSSFLRSITRA 190
                 689999999888888888******************99864 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 1.6
      AAA_16 106 a......................a 107
                 +                      +
  EEA21102.1 547 RaqsqsqpsrgraltrdgdnngaD 570
                 122222222333333333333343 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.28
      AAA_16  28 llsGesGvGKs 38 
                 l+sG +G+GK+
  EEA21102.1 647 LFSGKRGMGKT 657
                 789*******9 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.0     0.011        23      99     122 ..     167     190 ..     128     227 .. 0.81
   2 !    7.7   0.1    0.0016       3.1      49     100 ..     283     338 ..     277     341 .. 0.86
   3 ?   -0.9   0.1      0.69   1.4e+03      67     113 ..     613     657 ..     602     658 .. 0.61

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.011
                  TSEEEEECSTTSSHHHHHHHHCTT CS
  RsgA_GTPase  99 dktsvlvGqSGvGKStLinallpe 122
                   +t +++G   vGKS+++ +++  
   EEA21102.1 167 TRTLLICGYPNVGKSSFLRSITRA 190
                  48999*************999875 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0016
                  EEEEEE-GGG--HHH....HHHHHHHHHHHTTSEEEE--TTTHTTHHHHHHHCTTS CS
  RsgA_GTPase  49 pvivlnKiDlleeee....eleelkeelealgyevllvsaktkegleelkellkdk 100
                  + +v+nKiD+   e+    + e l + l++ ++e+l +s +t+eg++++k++  dk
   EEA21102.1 283 VFVVVNKIDVKRPEDldpeTKELLDSMLNQSNVEMLQLSCTTTEGVTNVKNAACDK 338
                  6799*******99999996667778899********************99876665 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 0.69
                  HHHHHHHHTTSEEEE--TTTHTTHHHHHHHCTTSEEEEECSTTSSHH CS
  RsgA_GTPase  67 elkeelealgyevllvsaktkegleelkellkdktsvlvGqSGvGKS 113
                  + +e+l++lg + +   a+++e+ ++  + ++    ++ G+ G+GK+
   EEA21102.1 613 SKAERLTKLGQKKMNRMARQGEADRH--QTVSLAKHLFSGKRGMGKT 657
                  55666666666666665554444443..34444456899******97 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.0   0.00072       1.4       2      42 ..     148     190 ..     148     204 .. 0.90
   2 ?   -4.9   7.1         9   1.8e+04     114     164 ..     470     536 ..     382     553 .. 0.44

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00072
      AAA_23   2 Lkienfrsf..rdqeidFskgltlItGpNGaGKTTildAikla 42 
                 L +e +r++  r  +id +    lI+G    GK+++l+ i+ a
  EEA21102.1 148 LYLEQVRQHlgRLPSIDPNTRTLLICGYPNVGKSSFLRSITRA 190
                 678999999855578************************9965 PP

  == domain 2  score: -4.9 bits;  conditional E-value: 9
      AAA_23 114 i......deleqfise......llgskkiilnlilflgqerfeefel.......kdkkerleelekelee 164
                        d   + ++e       ++ + i+ +++l++ + r  + ++       ++k +rl e+ek+l+ 
  EEA21102.1 470 AegfydsD---DSVEEaedaeiRMKADLIREKRVLMKNEARLRKSLKnraaiprSAKAKRLSEMEKALDN 536
                 11221121...11111112322344444455555555555532222233444445555566666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (660 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1032  (0.0575604); expected 358.6 (0.02)
Passed bias filter:                      560  (0.0312343); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.43
# Mc/sec: 4569.19
//
Query:       EEA21103.1  [L=296]
Description: acetyltransferase, GNAT family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.9e-12   45.4   0.0      1e-11   44.9   0.0    1.2  1  Acetyltransf_10  Acetyltransferase (GNAT) domain
    4.2e-11   43.1   0.0      1e-10   41.8   0.0    1.7  2  Acetyltransf_1   Acetyltransferase (GNAT) family
    2.2e-07   31.2   0.0    4.1e-07   30.3   0.0    1.4  1  Acetyltransf_7   Acetyltransferase (GNAT) domain
     0.0039   17.1   0.0     0.0081   16.1   0.0    1.4  1  FR47             FR47-like protein
     0.0086   16.2   0.0      0.022   14.8   0.0    1.7  1  Acetyltransf_9   Acetyltransferase (GNAT) domain
  ------ inclusion threshold ------
      0.031   14.4   0.0       0.05   13.7   0.0    1.3  1  Acetyltransf_4   Acetyltransferase (GNAT) domain


Domain annotation for each model (and alignments):
>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.9   0.0   3.4e-15     1e-11      38     126 ..     199     288 ..     186     289 .. 0.90

  Alignments for each domain:
  == domain 1  score: 44.9 bits;  conditional E-value: 3.4e-15
  Acetyltransf_10  38 eggkivGvielrdgshisllfVdpeyrgqGigkaLleaveeeaekdgikleltvnaspyavpfYeklGFkav.geeqeenGirfvpMeke 126
                      e+++ vG+    ++  ++ l+V+ e++++ +g+ L++ +++++++++i+ ++ + a+++ vpfYe lGF+++  + +++ G  + +M +e
       EEA21103.1 199 EEKNYVGHEDQGTTVALHSLAVKAEHQRKRVGSTLMKSYIQRIKEAQIADRVALLAHDHMVPFYEALGFENCgPSACTFGGGGWFDMVLE 288
                      5567888888888889***************************9999999**********************667899999999999775 PP

>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       3.2   9.7e+03      49      69 ..      49      73 ..      42      76 .. 0.59
   2 !   41.8   0.0   3.5e-14     1e-10      55     117 .]     199     267 ..     111     267 .. 0.67

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 3.2
                    EEEEEET....TSTTEEEEEEEEES CS
  Acetyltransf_1 49 sllkipd....ekggvayieslaVs 69
                    s+++  d    e++++++ + +aV+
      EEA21103.1 49 SFNPHGDdddeEDEDEGAEDYVAVD 73
                    4444444566666666666666665 PP

  == domain 2  score: 41.8 bits;  conditional E-value: 3.5e-14
                     T........TSTTEEEEEEEEESGGGTTSSHHHHHHHHHHHHHHHTTE.SEEEEEEETTEHHHHHHHHHTTE CS
  Acetyltransf_1  55 d........ekggvayieslaVspeyrgkGlGsaLlealeerareegi.kkivlaveedndaairlYeklGF 117
                     +          g +++++slaV+ e+++k +Gs+L++ +++r +e +i +++ l     +d+++++Ye lGF
      EEA21103.1 199 EeknyvgheDQGTTVALHSLAVKAEHQRKRVGSTLMKSYIQRIKEAQIaDRVAL---LAHDHMVPFYEALGF 267
                     144445555567889999****************************999**988...678999****99**9 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.3   0.0   1.4e-10   4.1e-07      25      75 ..     213     268 ..     196     269 .. 0.61

  Alignments for each domain:
  == domain 1  score: 30.3 bits;  conditional E-value: 1.4e-10
                     TCTEEEEE-GGGTTSSHHHHHHH.H....TTSEEEEE..EEEETHHHHHHHHHHTTEE CS
  Acetyltransf_7  25 aeitrlaVdpeyrgkGiGraLle.a....aekgiile..qlelnaekaikfYeklGFe 75 
                       ++ laV+ e+++k +G+ L++ +    +    ++   ++ l++++ ++fYe lGFe
      EEA21103.1 213 VALHSLAVKAEHQRKRVGSTLMKsYiqriK--EAQIAdrVALLAHDHMVPFYEALGFE 268
                     23455******************6444321..212222233332225588*******8 PP

>> FR47  FR47-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0   2.7e-06    0.0081      23      79 ..     214     269 ..     205     275 .. 0.87

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 2.7e-06
                 SEEEEEE-GGG-SSSHHHHHHHHHHHHHHHS-S-EEEEEETT-HHHHHHHHHHT-EE CS
        FR47  23 elgalqvlpehrrrGlgsrlvkalakeiaergktvllvvvasNtpsirlyeklGfek 79 
                 +l +l v+ eh+r+  gs l k+ +++i e+++   +   a+++    +ye+lGfe 
  EEA21103.1 214 ALHSLAVKAEHQRKRVGSTLMKSYIQRIKEAQIADRVALLAHDH-MVPFYEALGFEN 269
                 6889**************************99988887777665.589*******96 PP

>> Acetyltransf_9  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   7.4e-06     0.022      76     126 ..     215     268 ..     202     270 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 7.4e-06
                     EEEEEE-CCGTTS-HHHHHHHHHHHHHHHT..T--EEEE--.SSHHHHHTTT-E CS
  Acetyltransf_9  76 vtgVavapehrgrgvlskLlaraleemree..gqplsllfP.ssipiYrrfGye 126
                     + + av++eh+++ v s L++  +++++e    ++++ll     +p+Y+ +G+e
      EEA21103.1 215 LHSLAVKAEHQRKRVGSTLMKSYIQRIKEAqiADRVALLAHdHMVPFYEALGFE 268
                     66789************************9433455555557779********8 PP

>> Acetyltransf_4  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   1.7e-05      0.05      83     154 ..     219     286 ..     202     287 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.7e-05
  Acetyltransf_4  83 ylaerdnnkeglgrelidaleqvlkeqnienllaeiaspnensiqfhkalGFelvgifkkcikkngrwiDmi 154
                      ++    + + +g+ l+++ +q++ke  i   +a +a  ++  + f++alGFe+ g +  c   +g w+Dm+
      EEA21103.1 219 AVK-AEHQRKRVGSTLMKSYIQRIKEAQIADRVALLA--HDHMVPFYEALGFENCGPS-ACTFGGGGWFDMV 286
                     454.56888999999*******************999..88899************86.7999********8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (296 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 1942.27
//
Query:       EEA21104.1  [L=440]
Description: DNA damage-inducible v-SNARE binding protein Ddi1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-61  205.5   0.1    2.6e-61  204.9   0.1    1.3  1  Asp_protease     Aspartyl protease
    1.2e-22   80.2   0.0    2.9e-22   79.1   0.0    1.7  1  gag-asp_proteas  gag-polyprotein putative aspartyl protease
    7.1e-12   45.8   0.1      8e-11   42.4   0.0    2.6  3  Asp_protease_2   Aspartyl protease
    4.4e-11   42.4   0.0    9.2e-11   41.4   0.0    1.5  1  ubiquitin        Ubiquitin family
      6e-08   32.4   0.1    1.7e-07   31.0   0.0    1.9  2  UBA              UBA/TS-N domain
    0.00013   21.7   1.7    0.00064   19.5   0.0    2.3  2  Rad60-SLD        Ubiquitin-2 like Rad60 SUMO-like
    0.00014   22.1   0.4     0.0017   18.6   0.0    2.8  4  RVP              Retroviral aspartyl protease
     0.0022   17.7   0.0     0.0053   16.5   0.0    1.5  1  RVP_2            Retroviral aspartyl protease
     0.0065   16.3   0.0      0.014   15.2   0.0    1.5  1  UBA_4            UBA-like domain
  ------ inclusion threshold ------
      0.012   15.3   0.1       0.65    9.8   0.0    2.6  2  CUE              CUE domain
      0.021   15.1   2.0      0.047   14.0   2.0    1.6  1  acVLRF1          Actinobacteria/chloroflexi VLRF1 release fac
        1.8    8.8  11.6       0.17   12.1   5.5    2.4  3  DUF3947          Protein of unknown function (DUF3947)
          6    7.1  10.2        1.8    8.8   1.5    2.4  2  Snurportin1      Snurportin1


Domain annotation for each model (and alignments):
>> Asp_protease  Aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  204.9   0.1   1.8e-64   2.6e-61       1     124 []     196     319 ..     196     319 .. 0.99

  Alignments for each domain:
  == domain 1  score: 204.9 bits;  conditional E-value: 1.8e-64
  Asp_protease   1 qeaveenlekalehtPeafvkvtmlyinvevngvkvkafvdsGaqksilskkcaercglmrlldtrfkgiakGvGtkkilGrvhsaevklgdlflpv 97 
                   q+av+enl++a+eh+Pe+f++vtmlyi+vevng+++kafvdsGaq +i+s++ca  c++mrl+d+r+ giakGvGt+ki+Grvhsa++k+g++flp+
    EEA21104.1 196 QQAVTENLHNAMEHHPESFGRVTMLYIPVEVNGKPIKAFVDSGAQVTIMSPECAAACNIMRLVDQRYGGIAKGVGTAKIIGRVHSAQLKIGSMFLPC 292
                   689********************************************************************************************** PP

  Asp_protease  98 alsvledkevdlllGldllkrhqviid 124
                   +++v+e+k++dlllGld+l+rhq++id
    EEA21104.1 293 SFTVMEGKHIDLLLGLDMLRRHQACID 319
                   **************************8 PP

>> gag-asp_proteas  gag-polyprotein putative aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.1   0.0   2.1e-25   2.9e-22       1      92 []     222     313 ..     222     313 .. 0.95

  Alignments for each domain:
  == domain 1  score: 79.1 bits;  conditional E-value: 2.1e-25
                      EEEEETTEEEEEEEETT-SS-EEEHHHHHHTTGGGGEB..TT--EE-TTST.T-EEEEEEEEEE.EETTEEEEEEEEEESSSSEEEEHHHHHH CS
  gag-asp_proteas   1 vkvkingkpvkflvDTGAsstiiseelaerlglsrkedkgkvevktangev.eakrvrldsvkiggielrnvsavvlegelddlLLGldfLkr 92 
                      ++v++ngkp+k++vD+GA+ ti+s+e+a +++++r++d++ + ++++ g++  ++rv+ +++kig++ l  +s++v+eg+  dlLLGld+L+r
       EEA21104.1 222 IPVEVNGKPIKAFVDSGAQVTIMSPECAAACNIMRLVDQRYGGIAKGVGTAkIIGRVHSAQLKIGSMFLP-CSFTVMEGKHIDLLLGLDMLRR 313
                      689***********************************99999999999984569**************8.9*******************97 PP

>> Asp_protease_2  Aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.4   0.0   5.8e-14     8e-11       1      89 [.     222     309 ..     222     310 .. 0.87
   2 ?   -0.5   0.0       1.4     2e+03      11      37 ..     315     341 ..     312     370 .. 0.76
   3 ?   -1.9   0.0       3.8   5.3e+03      30      55 ..     372     398 ..     356     431 .. 0.69

  Alignments for each domain:
  == domain 1  score: 42.4 bits;  conditional E-value: 5.8e-14
  Asp_protease_2   1 vpvtinGkpvrfllDTGasttlispelaeklgl.kvreseltvrvsgaggevkarlvrldslklggltlknvpalvldlgeeidglLGmd 89 
                     +pv++nGkp+++++D+Ga++t++spe a+++++ +  ++++   ++g+g ++   +v+  +lk+g++ l    ++v++ g+ id+lLG+d
      EEA21104.1 222 IPVEVNGKPIKAFVDSGAQVTIMSPECAAACNImRLVDQRYGGIAKGVGTAKIIGRVHSAQLKIGSMFL-PCSFTVME-GKHIDLLLGLD 309
                     69*****************************884555555667778888888888899999*****888.699*****.99*******98 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 1.4
  Asp_protease_2  11 rfllDTGasttlispelaeklglkvre 37 
                     ++++D G ++++i ++++  lg    +
      EEA21104.1 315 QACIDLGRGALVIQDQAVPFLGEAEIP 341
                     6899*********99998777654444 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 3.8
  Asp_protease_2  30 klglkvreseltvrvsgagge.vkarl 55 
                     +++ ++ +++ + + +++gg+ +++  
      EEA21104.1 372 QAEKPPAQQAAQPQTRTLGGAsQPSTS 398
                     455556666666666777776333333 PP

>> ubiquitin  Ubiquitin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.4   0.0   6.6e-14   9.2e-11      10      69 ..      17      77 ..       3      78 .. 0.91

  Alignments for each domain:
  == domain 1  score: 41.4 bits;  conditional E-value: 6.6e-14
                EEEEEEETTSBHHHHHHHHHHHHTSSGGGEEEEETTEEE.-TTSBHGGHTTSTTEEEEEEE CS
   ubiquitin 10 kitleveesdtveelKekiaekegipaeqqrLiysGkvL.edertleeygiqdgstlhlvl 69
                 i+l+v+ + t+e lK+ i++  +ip++ qrL+y+ ++L +d +tle++gi +g+ l +++
  EEA21104.1 17 IISLDVAGDMTLEVLKAVIESDSNIPPSAQRLVYNNQLLsNDAQTLEQVGILEGDMLLVHV 77
                7899***************************************************998875 PP

>> UBA  UBA/TS-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.0       9.4   1.3e+04      28      34 ..     138     144 ..     137     144 .. 0.84
   2 !   31.0   0.0   1.2e-10   1.7e-07       3      37 .]     403     437 ..     402     437 .. 0.96

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 9.4
                 TSHHHHH CS
         UBA  28 nNeErAv 34 
                 +N+E+A+
  EEA21104.1 138 QNPELAA 144
                 69**996 PP

  == domain 2  score: 31.0 bits;  conditional E-value: 1.2e-10
                 HHHHHHHHHTTS-HHHHHHHHHHTTTSHHHHHHHH CS
         UBA   3 eeaiqrLveMGFdreevveALratgnNeErAveyL 37 
                 +++i+ + e+GF+re+++  L a+++N+++A+++L
  EEA21104.1 403 ASSINKITELGFSREQAISGLDASNGNVDQAINFL 437
                 6799******************************9 PP

>> Rad60-SLD  Ubiquitin-2 like Rad60 SUMO-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0   4.6e-07   0.00064       8      70 ..      13      75 ..       3      77 .. 0.86
   2 ?    0.7   0.6      0.33   4.6e+02      29      54 ..      98     124 ..      96     126 .. 0.77

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 4.6e-07
                SSS--EEEEEETTSBHHHHHHHHHHHHT----TT-EEEETTEE--TT.SBGGGSS--TTEEEEE CS
   Rad60-SLD  8 kdgkevkikVkptttvskLieayrkkkgipeeqkvrLiFDGeeLdpn.stvedldiedgdtidv 70
                +d + +++ V+ ++t++ L+ + ++  +ip+ + +rL+++++ L+++ +t+e+ +i +gd++ v
  EEA21104.1 13 SDADIISLDVAGDMTLEVLKAVIESDSNIPP-SAQRLVYNNQLLSNDaQTLEQVGILEGDMLLV 75
                455568899**********************.************76538************755 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.33
                 HHHHHHT----.TT-EEEETTEE--TT CS
   Rad60-SLD  29 ayrkkkgipee.qkvrLiFDGeeLdpn 54 
                 a++++++++++ q+++ +FD e+L+ n
  EEA21104.1  98 ALQRQQQLQQQqQQQQPLFDTETLRLN 124
                 567777777765888999**9999876 PP

>> RVP  Retroviral aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0       1.7   2.3e+03      49      89 ..      88     127 ..      83     129 .. 0.61
   2 !   18.6   0.0   1.2e-06    0.0017       8      98 ..     223     316 ..     220     319 .. 0.68
   3 ?   -0.1   0.0      0.86   1.2e+03      15      35 ..     313     333 ..     282     386 .. 0.76
   4 ?   -2.3   0.0         4   5.5e+03      35      61 ..     377     400 ..     361     417 .. 0.56

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 1.7
                 ETTEEEEEEEEEEEEEEETTEEEEE..EEEESTT.SSSEEE- CS
         RVP  49 Giggatevqqskaievllieekfrgevsplilpa.lpvnilG 89 
                 ++gg +   q  +++ +l+++++++  +pl   + l +n+lG
  EEA21104.1  88 SLGGPSASSQALQRQQQLQQQQQQQ--QPLFDTEtLRLNLLG 127
                 5666666666666666666666666..555554446677776 PP

  == domain 2  score: 18.6 bits;  conditional E-value: 1.2e-06
                 EEEETTEEEEEEE-TTBSSEEEES---SCE....EEEEEEEETTEEEEEEEEEEEEEEETTEEEEE..EEEESTTSSSE....EE-HHHHCCCT- CS
         RVP   8 kvkiggkyieallDtGAdatviseedwPenwpvkkaetllqGiggatevqqskaievllieekfrgevsplilpalpvn....ilGrdlLqqlgv 98 
                  v ++gk+i+a +D+GA++t++s e   +    + +++   Gi ++  ++ +  + v+ ++ k  + + p  +  +  +    +lG d+L+  ++
  EEA21104.1 223 PVEVNGKPIKAFVDSGAQVTIMSPECAAACNIMRLVDQRYGGIAKGVGTAKIIGR-VHSAQLKIGSMFLPCSFTVMEGKhidlLLGLDMLRRHQA 316
                 699*******************998887775669999999999888877776653.433333333323332222222224457888888887765 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.86
                 EEEEEE-TTBSSEEEES---S CS
         RVP  15 yieallDtGAdatviseedwP 35 
                 + +a +D G  a vi+++++P
  EEA21104.1 313 RHQACIDLGRGALVIQDQAVP 333
                 455666666666666666666 PP

  == domain 4  score: -2.3 bits;  conditional E-value: 4
                 SCE....EEEEEEEETTEEEEEEEEEE CS
         RVP  35 PenwpvkkaetllqGiggatevqqska 61 
                 P++   ++a+++ + +gga++   s+ 
  EEA21104.1 377 PAQ---QAAQPQTRTLGGASQPSTSSR 400
                 444...555555555555554444333 PP

>> RVP_2  Retroviral aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   3.8e-06    0.0053      27     131 ..     225     328 ..     212     331 .. 0.83

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 3.8e-06
       RVP_2  27 lvnsipatvLfdsGasHsFiskafvsklklkveaLstpllietPvgssvtakeicksveieiqgiefladlilLdlkdlDviLgmdWLsknkanidcae 125
                  vn+ p +   dsGa    +s +++   ++     +    i   vg   ++    +s +++i ++ ++    +++ k++D++Lg+d L +++a id  +
  EEA21104.1 225 EVNGKPIKAFVDSGAQVTIMSPECAAACNIMRLVDQRYGGIAKGVGTAKIIG-RVHSAQLKIGSMFLPCSFTVMEGKHIDLLLGLDMLRRHQACIDLGR 322
                 5899999999999999999999999999887666566666777766655544.458899*************************************988 PP

       RVP_2 126 kkvtlt 131
                  +++++
  EEA21104.1 323 GALVIQ 328
                 777665 PP

>> UBA_4  UBA-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0     1e-05     0.014      12      34 ..     413     435 ..     408     437 .. 0.91

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1e-05
       UBA_4  12 GadeekArqlLeannWdLerAis 34 
                 G+++e+A++ L+a+n+++++Ai+
  EEA21104.1 413 GFSREQAISGLDASNGNVDQAIN 435
                 78********************8 PP

>> CUE  CUE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.0     0.069        95      12      38 ..      23      48 ..      20      52 .. 0.78
   2 ?    9.8   0.0   0.00047      0.65      24      39 ..     423     438 ..     414     440 .] 0.85

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.069
                STTS-HHHHHHHHHHCTTTHHHHHHHH CS
         CUE 12 FPdldeevIravLrasngnvEatinaL 38
                  d++ ev++av  +s+ n+ +   +L
  EEA21104.1 23 AGDMTLEVLKAVI-ESDSNIPPSAQRL 48
                5699*********.***9997665555 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00047
                 HHHCTTTHHHHHHHHH CS
         CUE  24 LrasngnvEatinaLL 39 
                 L asngnv+++in LL
  EEA21104.1 423 LDASNGNVDQAINFLL 438
                 89**********9776 PP

>> acVLRF1  Actinobacteria/chloroflexi VLRF1 release factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   2.0   3.4e-05     0.047      14     119 ..      64     168 ..      54     177 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 3.4e-05
     acVLRF1  14 avgvveggelvaskvgtrdvqgrtaaGGwSqqRfaRrrenqadalleavaeaaarllaeesaevvlgGdrslvaevled.arlaplatlare..elldv 109
                 +vg++eg+ l+ +++g r   ++ + GG S +  a +r++q ++  ++     + l++ e+ ++ l Gd++++++v+ + ++la++a+ +r+  e+l  
  EEA21104.1  64 QVGILEGDMLLVHVGGGRPQPTSRSLGGPSASSQALQRQQQLQQQQQQQ----QPLFDTETLRLNLLGDPRVMETVRRQnPELAAAAEDPRRfqEVLLS 158
                 699***************************9999999999988877665....5566688899***************977799999999998888878 PP

     acVLRF1 110 pdprravLed 119
                 ++ r++ Le 
  EEA21104.1 159 QKRREQELER 168
                 8888888875 PP

>> DUF3947  Protein of unknown function (DUF3947)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   5.5   0.00012      0.17      30      53 ..      94     117 ..      85     124 .. 0.88
   2 ?   -3.2   0.0       7.3     1e+04      21      30 ..     236     245 ..     232     251 .. 0.76
   3 ?   -1.9   0.1       2.9     4e+03      11      37 ..     354     384 ..     345     401 .. 0.56

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00012
     DUF3947  30 avqqalqmqqqaqmqqsqiqPyss 53 
                 a  qalq qqq+q qq+q qP ++
  EEA21104.1  94 ASSQALQRQQQLQQQQQQQQPLFD 117
                 779******************876 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 7.3
     DUF3947  21 laGaqstvqa 30 
                  +Gaq t+ +
  EEA21104.1 236 DSGAQVTIMS 245
                 5899999865 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 2.9
     DUF3947  11 mrpayGaaitlaGaqstvqa....vqqalqm 37 
                 +r a Ga i       t qa     qqa q 
  EEA21104.1 354 IRGADGAEIGARSGAVTHQAekppAQQAAQP 384
                 5667777775433334444411112333333 PP

>> Snurportin1  Snurportin1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   1.8      0.11   1.5e+02      12      30 ..      93     111 ..      90     118 .. 0.84
   2 ?    8.8   1.5    0.0013       1.8      17      30 ..     159     172 ..     153     178 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.11
  Snurportin1  12 saldQeeRRrrlLerqKek 30 
                  sa++Q+  R++ L++q ++
   EEA21104.1  93 SASSQALQRQQQLQQQQQQ 111
                  6789**********99887 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0013
  Snurportin1  17 eeRRrrlLerqKek 30 
                  ++RR++ LerqKe+
   EEA21104.1 159 QKRREQELERQKEA 172
                  58**********96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (440 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       862  (0.0480785); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.48
# Mc/sec: 2760.91
//
Query:       EEA21105.1  [L=177]
Description: integral membrane protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-36  125.5  10.2    2.4e-36  125.3  10.2    1.0  1  DUF2781   Protein of unknown function (DUF2781)


Domain annotation for each model (and alignments):
>> DUF2781  Protein of unknown function (DUF2781)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  125.3  10.2   1.3e-40   2.4e-36       1     147 []      11     159 ..      11     159 .. 0.91

  Alignments for each domain:
  == domain 1  score: 125.3 bits;  conditional E-value: 1.3e-40
     DUF2781   1 DlvyllyflihipitllvDlqvllpaslfp......hflsk.lrewyiatnnDpllleppaWfksfvllelffqlPlffiavyaLlkkekpwlrllllv 92 
                 Dl++l++f++h++++ +vD+  l+p++l +        + + lr++y++t++D+l++e+p Wf +f+++el+f++P+++++v++L+   +p ++l ++ 
  EEA21105.1  11 DLLILIFFSLHLFFVTCVDCLDLWPTWLSSspylpfFGVGRvLRDFYLETYQDKLVAEQPGWFVVFTWCELLFHVPVCVWVVRGLVI-DSPLVPLGVIS 108
                 899**********************77763357765333346********************************************4.69********* PP

     DUF2781  93 YgvhaatttlaciaellsegeavasesekqklkllalylpylliPlllavdmllr 147
                 + v++++ttl+c++e++++++    +s++ k+ l+++y+pyl+i+++l+v m+ r
  EEA21105.1 109 WTVETFFTTLPCVVEIWKWDD----RSDEIKWGLTGCYGPYLVISAWLFVLMYGR 159
                 ********************9....588889*******************99865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (177 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       361  (0.020135); expected 358.6 (0.02)
Passed bias filter:                      233  (0.0129957); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.28s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 1260.88
//
Query:       EEA21106.1  [L=145]
Description: hypothetical protein PMAA_049110 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.098   12.9   0.0       0.16   12.2   0.0    1.3  1  PPR_2     PPR repeat family


Domain annotation for each model (and alignments):
>> PPR_2  PPR repeat family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   8.8e-06      0.16       5      37 ..      74     106 ..      71     108 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 8.8e-06
       PPR_2   5 tyNtlIsglckkgkveeAfklfneMkkrglePn 37 
                 +y +lI +l  +g +eeA + +++ +k g+  +
  EEA21106.1  74 AYMSLIYYLESQGLYEEANDHMEDLRKAGIDAD 106
                 799***9999*******************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (145 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       434  (0.0242066); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.35s 00:00:00.92 Elapsed: 00:00:00.56
# Mc/sec: 774.77
//
Query:       EEA21107.1  [L=172]
Description: hypothetical protein PMAA_049120 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
      0.069   13.2   0.0       0.09   12.8   0.0    1.1  1  Smg4_UPF3  Smg-4/UPF3 family


Domain annotation for each model (and alignments):
>> Smg4_UPF3  Smg-4/UPF3 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0     5e-06      0.09     108     145 ..      81     118 ..      66     131 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 5e-06
   Smg4_UPF3 108 akqgtIekDpeylaFleslekeeeekeseseeeklaee 145
                 + + tIe D+ y++F ++l++e +++e+++   +l+e+
  EEA21107.1  81 TDNLTIELDQRYMSFAHTLKDEGNHDEAADVLRELREN 118
                 5566****************999998777755555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (172 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       576  (0.0321267); expected 358.6 (0.02)
Passed bias filter:                      461  (0.0257125); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.37s 00:00:00.95 Elapsed: 00:00:00.56
# Mc/sec: 925.82
//
Query:       EEA21108.1  [L=334]
Description: 4-hydroxybenzoate octaprenyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-35  123.2  14.0    1.4e-35  122.8  14.0    1.1  1  UbiA      UbiA prenyltransferase family
  ------ inclusion threshold ------
       0.21   10.9   3.6          1    8.7   0.2    2.2  2  DUF1616   Protein of unknown function (DUF1616)


Domain annotation for each model (and alignments):
>> UbiA  UbiA prenyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  122.8  14.0   1.5e-39   1.4e-35      19     246 ..      61     305 ..      40     313 .. 0.84

  Alignments for each domain:
  == domain 1  score: 122.8 bits;  conditional E-value: 1.5e-39
        UbiA  19 l....llllllllgtllaaaaanalNdyfDreiDadmertpnRPlvsGrispkealifaivllilgllllalllnpltallgllalllyvvYtglrlKr 113
                      +l+++l++ t+++++ a+++Nd+fD ++D+++ert+ RPl+++++s+ +a++f+++l+++  +l  + l   +   + l  l++++Y+    Kr
  EEA21108.1  61 VlvvvSLAVFLAIWTVVLRGVACTWNDIFDQDFDRQVERTRFRPLARRAVSTTQAVLFSLFLMVILGVLC-VPLPSASRNYAGLKTLVLCLYP--LAKR 156
                 2444455666666666**********************************************99987777.888888889999999999****..**** PP

        UbiA 114 rtllgtvvggiafglppllgwaavtgsl................sllalllalavflltwaialandlrdregDrkagiktlpvvlGrkaaril.lall 195
                 +t+l++vv+g+  +l +l+ +++ +++                  l ++ +++a++++t+  +++++++d+ +D kag+k+l+v+lG ++ ++l +++ 
  EEA21108.1 157 ITHLPQVVLGFGLALSVLMCVTILSEDPplrarhggdesssspsFLSVVSFYFACAIWTIISDTIYAHQDLTDDIKAGVKSLAVLLGGRTILYLsVLST 255
                 ***************************9*************9754455555566777777778888***************************953334 PP

        UbiA 196 lavlllallllllalllllylllalllaalallraarlvrrrdakkaakff 246
                 + v+ll +l+ + ++++ +y+l++ l  a  l   +  v+ r+++++a +f
  EEA21108.1 256 IQVALL-VLAGTECGYSFFYYLICCLGTACSLGTMLIKVDLRQPDSCAWWF 305
                 444444.5789999*********************************9988 PP

>> DUF1616  Protein of unknown function (DUF1616)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.4    0.0053        48      81     153 ..      56     128 ..      39     141 .. 0.70
   2 ?    8.7   0.2   0.00011         1      39      74 ..     146     181 ..     145     221 .. 0.88

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.0053
     DUF1616  81 irlepilvslslftlllalvAivrRsrlpeeerfsvplralieslkeeleeksesrldkalnvlLvvsivlav 153
                  +l  +lv++sl ++l+++  ++r  ++  ++ f  ++++ +e+++ +   + +  +++a+ + L + ++l v
  EEA21108.1  56 PTLPDVLVVVSLAVFLAIWTVVLRGVACTWNDIFDQDFDRQVERTRFRPLARRAVSTTQAVLFSLFLMVILGV 128
                 4555688888888888888889999999999999999999888888877777444455555555555555544 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.00011
     DUF1616  39 liaaLFPekrdidgieRlaLSfglSiaivpliglvl 74 
                 l+  L+P  ++i+++  ++L fgl + +++ ++++ 
  EEA21108.1 146 LVLCLYPLAKRITHLPQVVLGFGLALSVLMCVTILS 181
                 8999*************************9998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (334 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       747  (0.0416643); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.47
# Mc/sec: 2154.94
//
Query:       EEA21109.1  [L=1351]
Description: non-repetitive nucleoporin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.9e-92  310.3   1.9    3.3e-92  309.5   1.9    1.4  1  Nucleoporin_N  Nup133 N terminal like
      5e-51  174.2   4.6    8.1e-50  170.2   1.5    2.1  2  Nucleoporin_C  Non-repetitive/WGA-negative nucleoporin C-term


Domain annotation for each model (and alignments):
>> Nucleoporin_N  Nup133 N terminal like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  309.5   1.9   3.7e-96   3.3e-92       2     434 .]     108     558 ..     107     558 .. 0.96

  Alignments for each domain:
  == domain 1  score: 309.5 bits;  conditional E-value: 3.7e-96
                    E-SCEEEEEEE--HCHHHTTS--SS-EEEEEECTTTEEEEEETTEEEEEETTSSSS...EEEEEE----S---EEEEEE---SSSS-SSSCEEEEE CS
  Nucleoporin_N   2 etdfykvsklalPdelleelnhtesstkgglfpeigrawitvdnklflWnYnstasspstdtipydgeehtilavglLvkpkpgtfveevgllLvv 97 
                    + +f+k++ +++Pd++++++n ++ st++glf+e++ aw+++dn+l+lW+Y+++     ++ + y++++++i av+ L kp+pg+f ++++++Lv+
     EEA21109.1 108 WAPFHKIKMYNIPDQIFDQYNRAQVSTSMGLFAELNHAWVAIDNALYLWDYTHPN----PQLVGYESQPNSINAVK-LAKPRPGVFLPSITHILVI 198
                    789*****99********************************************9....9****************.******************* PP

                    CTTSEEEEECECCS--------EEEEEEEE--EETT.TTEEEEEEETTTC-EEEEETTS.SEEEEEEC-SSS-CEEEEEEEEE-SSSS-...--SS CS
  Nucleoporin_N  98 attgeivyweviysaasllstnelslfntdlsvssdgeivtqvinseptgriflagstg.rlyeltyrdssgwpslkckkicltkgglssllsilp 192
                    +tt ei++++  ++  s    ++++l++t++s+s  g++v  +++s+ tgrif+a+s++ ++ye++y++++ w++ +c+k++ t++ +    s+ p
     EEA21109.1 199 STTAEIILLGMGCETVSG-GAKQVTLYQTGMSTSIRGLDVHVITSSDTTGRIFFASSSDnDVYEFKYQQEEKWFQGRCSKVNQTSSRIT---SFAP 290
                    **********99988554.79**************************************9*****************************...**** PP

                    S--G----GG-EEEEEEECCTCEEEEEETTSEEEEEEEETTCEE-EEEEEEEHHHHHHHH.HHSCHTTTCGCTTT-EEEEEEES-TTTSSCEEEEE CS
  Nucleoporin_N 193 gvlsgasereeivqlridssrrilytlsskgvirvydlsasngesslksdidirqilleaitesliasaplaskslkildispvsaeessllhlva 288
                    ++  ++++ e++ q+++d++r++lytlss ++irv++l  + g+  l  ++ + +i+++   +++i s+ + + ++ki++ispv+  e+s  hlva
     EEA21109.1 291 SLSFTQKPTESVEQMVVDDTRNLLYTLSSLSTIRVFHLK-PDGSLALAITKPVIDIYSNI--GHIIPSNEALNPKVKIVSISPVPTPEASRYHLVA 383
                    **99***********************************.76888888888888888877..7789999999999********************* PP

                    EECSSSEEEEEEEEE........EEECTTT-EEEEEEEEE.......EEEECCCCCSSSSSSSBECC-CC...SSETTCEEEEEEES-...-SEEE CS
  Nucleoporin_N 289 itsngvrlylllsss........ssdspsalslvsvrfpp.......krlntysskllenkkksklllps...kiispgiflfvvfdk...ssavv 363
                     t++g r+yl+++ s          ++p++++  +v+ pp          +++ ++++++k ++  l p+   + ++pg f++ + +    +++++
     EEA21109.1 384 TTATGYRIYLSATGSyswsptpsGTSPPTSMQAHFVKTPPfdtpaavPGAMQFQQTATTTKVPIHTLDPTrlaQQFPPGYFFCFTCKDpsqKEDTL 479
                    **********************9999*******************999999999999999999*********************9999999***** PP

                    EEEEEE-TTTTSSS.......ESEEEECCS--SE-EEEEE--T--T--CCCCCCSSTTCTTT.TS---EEEETTTEEEE CS
  Nucleoporin_N 364 lvslpdtgilkksq.......lvedasflpldgkwediislrksfdatilpsgyenesatqy.keParvalltntGvvi 434
                    ++s+pd+g++  ++        +e+a +l+l ++ edi  ++ +++a  + +g++ne+a qy +++a++a+ltntGv+i
     EEA21109.1 480 FISAPDSGRIARAHenvvppkPSESAIWLSLGSRAEDIGLITTPLTAVASANGFGNELAIQYdQSAAEFAILTNTGVHI 558
                    *************9************************************************999999*********97 PP

>> Nucleoporin_C  Non-repetitive/WGA-negative nucleoporin C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.0   0.1   0.00095       8.5      13      45 ..     710     753 ..     699     765 .. 0.89
   2 !  170.2   1.5     9e-54   8.1e-50     180     595 ..     794    1230 ..     789    1231 .. 0.92

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.00095
                    XXXXXXXXXXXXXXXXXXX...........XXXXXXXXXXXXXX CS
  Nucleoporin_C  13 ssLeiLaeflksngeslsr...........dtrwellwqAEkia 45 
                      L+ L ef+k+n++ +++           ++++e+++qAE+ a
     EEA21109.1 710 RDLSALQEFFKANKNFIEGlsgpealsraaTKQEEVALQAEHRA 753
                    67999*************************************88 PP

  == domain 2  score: 170.2 bits;  conditional E-value: 9e-54
                     XXXXXXXXXXXXX.........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHHHHHHHHHHHHHHH......HHHHHHHHHHXXXXXXX CS
  Nucleoporin_C  180 Ltklllkdlfapn.........lssiinrnisrgesieleatllqeicgslcsltdvllfraiErlrwake......qkdkklqnaikllekay 258 
                     ++kl++++lf++          + +i+nrni++g++ e+ a +l+++cg++cs+ dv++f+a E l++a e        ++ l+++ +l+++  
     EEA21109.1  794 FLKLTFEELFSTGkgyeiakelVKAIVNRNIAKGSNVETVADALRRRCGNFCSAEDVIIFKAQELLKRATEaganseIGRNLLNESLRLFRQVS 887 
                     7899999999999999***99999**************************************************99999999************ PP

                     XX.........XXXHHHHHHHHHHHHTSXHHHHHHHHHHHHH..HHHXSSSSXHHHH......HHHHHHH........................ CS
  Nucleoporin_C  259 dearkeqilkLlsigkleeaielaekledfralvellleianklasdkgederkelyekaeelekriely........................ 328 
                     +e         l +++l +a++     +++ ++++l+l+ a+  +sdk + + + + + ++e ++r  +y                        
     EEA21109.1  888 EE---------LPMDNLVSAVDSYIANQFYAGAIQLCLNVAS--NSDKANLALNWMMDGRQEEDARKIHYafrkqcydlifkivvavdksaatd 970 
                     **.........******************************9..777775555555555555555555555555555889999*********** PP

                     ......................SSSXXHHHHHHHHHHHHHTTXGGGGGGX..XXTTHHHHHHHTX....XHHHHHHTHHHHXXSHHHHHHHHHH CS
  Nucleoporin_C  329 ......................fekfgkaFayalYdwlisqgqqekLLdlkedtsfilpFLrekp....elakllWiydvkekdfeeAAeiLys 396 
                                            +++++ F + lYdw+++qg +++LL    +++f+  +L+ k+      a+llW y+++ +++++AA++ ++
     EEA21109.1  971 pgvidgqytplakrrneaynviSDSNDEVFLTSLYDWYLEQGWSDRLLAT--QSPFVVTYLERKSvddiFHADLLWRYYAQSERYFDAARVQFQ 1062
                     *********************999**************************..***************9989*********************** PP

                     HHSSSSXXXHHHHHH.HHHHX---HHH................HGGGHHHHHHHHHHHHHHHH.......................H-TT..S- CS
  Nucleoporin_C  397 Lalskeqlvlskrie.LSlakLaqLaeleesekekkglekklekieellevaaiQddllalilpsiegaidekaeveLamekfgkklderpalr 489 
                     La s ++l ls+rie L  a+ a  ++  + e  +++ ++ l+ i +l++va+iQddll+  +                        der  l+
     EEA21109.1 1063 LAQSAFTLPLSRRIEyLGQAR-ANAST-FTPEIGRQSRQRLLQEIGNLMDVANIQDDLLQRLK-----------------------EDER--LN 1129
                     *****************9997.44444.4455555578999**********************.......................****..** PP

                     HHHHHHHHHHHHHS---HHHHHHHTT.........TTTT-HHHHHHHHHHTT---HHH............HHHHHHHHHHHHHHH-........ CS
  Nucleoporin_C  490 qllkdelkklLkhkildasdLidlltLidtkeeeedplgefelALkvlkvsdlrneeeealekliWRRcvIrddWeelnetkkked........ 575 
                     ++ kd++ k++++ i d++ L++ ++         d +g+  ++L++  ++d+rn ++            I++ We+l e  +++         
     EEA21109.1 1130 KESKDSVLKEIDGPIQDLTLLFNRYA---------DAGGYCDICLQIYYAADHRNMTD------------ILSTWENLIELTHEQTvakglaqp 1202
                     **************************.........***********************............********999877778******* PP

                     ........HHHHHHHTT-TTTS-HHHHH CS
  Nucleoporin_C  576 ........akvekklsstalvftlsell 595 
                             ++++++l+++++vf++ ++l
     EEA21109.1 1203 yeaviekiRSLGSRLRMSEIVFPVPSIL 1230
                     ***********************98775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1351 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       718  (0.0400469); expected 358.6 (0.02)
Passed bias filter:                      621  (0.0346366); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.94u 0.35s 00:00:01.29 Elapsed: 00:00:00.54
# Mc/sec: 7583.98
//
Query:       EEA21110.1  [L=180]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-23   83.5   3.0    1.7e-23   83.3   3.0    1.0  1  YqeY      Yqey-like protein


Domain annotation for each model (and alignments):
>> YqeY  Yqey-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.3   3.0   9.6e-28   1.7e-23       2     143 .]      30     177 ..      29     177 .. 0.93

  Alignments for each domain:
  == domain 1  score: 83.3 bits;  conditional E-value: 9.6e-28
                 HHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHHHHTTSS--HHHHHHHHHHHHHHHHHHHHHHHHHT-HHHHHHHHHHHHHHGGGS-..----HHHHHH CS
        YqeY   2 eklkedlkeamkakdkerlstlrllkaaikqeevderkelsdeevlkvlakevkqRresieefekagRedlaekekaEievleeYlP..eqlseeeiea 98 
                  kl++dlk+am+akd+ rl++lr l ++ +++  +++   +d ++l++++k++   ++++e+f +a+R+dl eke+a i++ eeY    + ++ e+i+a
  EEA21110.1  30 AKLRSDLKDAMRAKDTPRLNVLRALISETNNAAKTASPIATDLQLLSLIKKKIAASKDAAEQFLNANRSDLKEKEDAQITIFEEYAGqvQTMTAEDIKA 128
                 589****************************99999999**********************************************862268******** PP

                 HHHHHHHHTT--BGGGHHHHHHHHHH...HHTTT.S-HHHHHHHHHHH- CS
        YqeY  99 lvkeaiaevgaesmkdmGkvmkalkp...kvkGk.aDgkkvsalvkekL 143
                 +v+++i+++g   + ++G v+k + +    + Gk a+ ++v ++vke+L
  EEA21110.1 129 AVTSTISQLGTDAKLNVGVVLKNIFApggALDGKpAEKSEVAQIVKELL 177
                 **********************997633368898668999999999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (180 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       921  (0.0513693); expected 358.6 (0.02)
Passed bias filter:                      511  (0.0285013); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1302.80
//
Query:       EEA21111.1  [L=252]
Description: 5-formyltetrahydrofolate cyclo-ligase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.3e-36  126.2   0.0    2.2e-36  125.5   0.0    1.3  1  5-FTHF_cyc-lig  5-formyltetrahydrofolate cyclo-ligase family


Domain annotation for each model (and alignments):
>> 5-FTHF_cyc-lig  5-formyltetrahydrofolate cyclo-ligase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  125.5   0.0   1.2e-40   2.2e-36       1     186 [.      18     241 ..      18     242 .. 0.87

  Alignments for each domain:
  == domain 1  score: 125.5 bits;  conditional E-value: 1.2e-40
                     HHHHHHHHHHHHHTS-HHHHHHHHHHHHHHHHTSHHHHH-SEEEE----.TTS---HHHHHHHHHTTEEEEEEEECSSC..........TEECEE CS
  5-FTHF_cyc-lig   1 KqelRkqllaalralseeevaaesealsqrieslkesqeakrvalyvsv.kgeidtkelikklleegkevllPrvrles..........gslkvv 84 
                     K+elR+++++ l+ +  e+v+a+s  + +++  l+e+ +a+r+++++s+  gei+t+ +++++l++gkev++P++++ +          + ++++
      EEA21111.1  18 KKELRRKIQNLLKDVPRESVNAQSTVVANKLFTLPEYLNARRISIFLSMpTGEISTTGIVRDALSKGKEVFIPYTHKLEttgnpsqpkvSVMDML 112
                     89***********************************************889**********************9998889********999999 PP

                     EEEECCCCCCCCCHCTS................SCE--TTECCBCGGG...............G-SEEEE--SEEETTS-EE-SSTTHHHHHHHH CS
  5-FTHF_cyc-lig  85 rlttlkeedslesgkyg................lkePeeeeerelale...............kldlvlvPgvAfdkeGaRlGkGkGyyDrflar 148
                     rl++ +e +sl+  ++g                                               ldl+++Pg+Afd++  RlG+GkGyyD fl++
      EEA21111.1 113 RLESMEEFESLQPDNWGipsldkqsipnrqnclG-------------GtgvleerprgnpddlGLDLIVMPGMAFDTDFQRLGHGKGYYDYFLNN 194
                     9999999999999999966665555555554431.............03444444444555679******************************* PP

                     HTS.T-S.....S--EEEEE--GGGEES...-----ST----SEEE- CS
  5-FTHF_cyc-lig 149 lkg.gag.....dkpltvglaldeqlve...rlPleehDvpvdevvt 186
                     +++ +ag     ++p++v++al+eq+v+   ++P+ +hD+pvd +++
      EEA21111.1 195 YSKeIAGsprasQRPYLVAIALKEQIVNppdEIPVASHDQPVDVIIV 241
                     *9977543333389*************99999*************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (252 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       630  (0.0351386); expected 358.6 (0.02)
Passed bias filter:                      598  (0.0333538); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 1631.90
//
Query:       EEA21112.1  [L=217]
Description: 5-formyltetrahydrofolate cyclo-ligase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.5e-28   99.9   0.0    2.6e-28   99.1   0.0    1.3  1  5-FTHF_cyc-lig  5-formyltetrahydrofolate cyclo-ligase family


Domain annotation for each model (and alignments):
>> 5-FTHF_cyc-lig  5-formyltetrahydrofolate cyclo-ligase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.1   0.0   1.5e-32   2.6e-28       1     152 [.       8     189 ..       8     195 .. 0.86

  Alignments for each domain:
  == domain 1  score: 99.1 bits;  conditional E-value: 1.5e-32
                     HHHHHHHHHHHHHTS-HHHHHHHHHHHHHHHHTSHHHHH-SEEEE----.TTS---HHHHHHHHHTTEEEEEEEECSSC..........TEECEE CS
  5-FTHF_cyc-lig   1 KqelRkqllaalralseeevaaesealsqrieslkesqeakrvalyvsv.kgeidtkelikklleegkevllPrvrles..........gslkvv 84 
                     K+elR+++++ l+ +  e+v+a+s  + +++  l+e+ +a+r+++++s+  gei+t+ +++++l++gkev++P++++ +          + ++++
      EEA21112.1   8 KKELRRKIQNLLKDVPRESVNAQSTVVANKLFTLPEYLNARRISIFLSMpTGEISTTGIVRDALSKGKEVFIPYTHKLEttgnpsqpkvSVMDML 102
                     89***********************************************889**********************9998889********999999 PP

                     EEEECCCCCCCCCHCTS................SCE--TTECCBCGGG...............G-SEEEE--SEEETTS-EE-SSTTHHHHHHHH CS
  5-FTHF_cyc-lig  85 rlttlkeedslesgkyg................lkePeeeeerelale...............kldlvlvPgvAfdkeGaRlGkGkGyyDrflar 148
                     rl++ +e +sl+  ++g                                               ldl+++Pg+Afd++  RlG+GkGyyD fl++
      EEA21112.1 103 RLESMEEFESLQPDNWGipsldkqsipnrqnclG-------------GtgvleerprgnpddlGLDLIVMPGMAFDTDFQRLGHGKGYYDYFLNN 184
                     9999999999999999966665555555554431.............03444444444555679******************************* PP

                     HTS.T CS
  5-FTHF_cyc-lig 149 lkg.g 152
                     +++ +
      EEA21112.1 185 YSKeI 189
                     *9933 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (217 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       334  (0.018629); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1404.03
//
Query:       EEA21113.1  [L=227]
Description: 5-formyltetrahydrofolate cyclo-ligase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.8e-28   99.7   0.0      3e-28   98.9   0.0    1.3  1  5-FTHF_cyc-lig  5-formyltetrahydrofolate cyclo-ligase family


Domain annotation for each model (and alignments):
>> 5-FTHF_cyc-lig  5-formyltetrahydrofolate cyclo-ligase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.9   0.0   1.7e-32     3e-28       1     152 [.      18     199 ..      18     205 .. 0.86

  Alignments for each domain:
  == domain 1  score: 98.9 bits;  conditional E-value: 1.7e-32
                     HHHHHHHHHHHHHTS-HHHHHHHHHHHHHHHHTSHHHHH-SEEEE----.TTS---HHHHHHHHHTTEEEEEEEECSSC..........TEECEE CS
  5-FTHF_cyc-lig   1 KqelRkqllaalralseeevaaesealsqrieslkesqeakrvalyvsv.kgeidtkelikklleegkevllPrvrles..........gslkvv 84 
                     K+elR+++++ l+ +  e+v+a+s  + +++  l+e+ +a+r+++++s+  gei+t+ +++++l++gkev++P++++ +          + ++++
      EEA21113.1  18 KKELRRKIQNLLKDVPRESVNAQSTVVANKLFTLPEYLNARRISIFLSMpTGEISTTGIVRDALSKGKEVFIPYTHKLEttgnpsqpkvSVMDML 112
                     89***********************************************889**********************9998889********999999 PP

                     EEEECCCCCCCCCHCTS................SCE--TTECCBCGGG...............G-SEEEE--SEEETTS-EE-SSTTHHHHHHHH CS
  5-FTHF_cyc-lig  85 rlttlkeedslesgkyg................lkePeeeeerelale...............kldlvlvPgvAfdkeGaRlGkGkGyyDrflar 148
                     rl++ +e +sl+  ++g                                               ldl+++Pg+Afd++  RlG+GkGyyD fl++
      EEA21113.1 113 RLESMEEFESLQPDNWGipsldkqsipnrqnclG-------------GtgvleerprgnpddlGLDLIVMPGMAFDTDFQRLGHGKGYYDYFLNN 194
                     9999999999999999966665555555554431.............03444444444555679******************************* PP

                     HTS.T CS
  5-FTHF_cyc-lig 149 lkg.g 152
                     +++ +
      EEA21113.1 195 YSKeI 199
                     *9933 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (227 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       558  (0.0311228); expected 358.6 (0.02)
Passed bias filter:                      528  (0.0294495); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.40
# Mc/sec: 1698.83
//
Query:       EEA21114.1  [L=241]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-95  317.5   0.0    3.9e-95  317.3   0.0    1.0  1  Rot1      Chaperone for protein-folding within the ER, fungal


Domain annotation for each model (and alignments):
>> Rot1  Chaperone for protein-folding within the ER, fungal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  317.3   0.0   2.2e-99   3.9e-95       1     208 [.      29     237 ..      29     238 .. 0.95

  Alignments for each domain:
  == domain 1  score: 317.3 bits;  conditional E-value: 2.2e-99
        Rot1   1 lvGtWssksnkvltGpgfydpveekliePsltGisysFteDGfyEealyrvvanpknpsCpkavlqfqHGtyeleangslvltPievDGRqllsdpCkk 99 
                 l+GtWssks++v+tGp+fydpv + + eP ltGisysFt+DG+yEea+yr++ np++p+Cpk+++q+qHGty++++ngsl l Pi +DGRql+sdpC+ 
  EEA21114.1  29 LTGTWSSKSRQVVTGPDFYDPVADIFQEPPLTGISYSFTDDGHYEEAYYRAIPNPTQPQCPKGIMQWQHGTYSIQNNGSLALVPIPSDGRQLISDPCAG 127
                 79************************************************************************************************* PP

        Rot1 100 kkstytrynqselfkkyevlvdeyhgvkrlnlyqfdgspmqplylaykppqmlPtetlnptekasekvkrsleseeklkk.navkkkeeslnadklwwv 197
                  +styt+ynqs lf++y++++d+yhg++rl+l+qfdgspmqply+ y+pp mlPt++lnpt ka+ k+kr+++ + k ++ +++ ++ + +  +++ww+
  EEA21114.1 128 YHSTYTHYNQSVLFESYRIYMDKYHGIQRLDLVQFDGSPMQPLYILYRPPAMLPTTMLNPTGKARGKAKRAVAIDGKENQvSSMIRSVDPVVLERWWWF 226
                 ************************************************************************87555444044444458888******* PP

        Rot1 198 gvlllavgsva 208
                 g++ ++vg+++
  EEA21114.1 227 GIISTSVGGLV 237
                 ********986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (241 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       349  (0.0194657); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1683.25
//
Query:       EEA21115.1  [L=94]
Description: small nuclear ribonucleoprotein SmE, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-13   49.6   0.1    2.8e-13   49.3   0.1    1.1  1  LSM       LSM domain
     0.0013   18.4   0.1     0.0019   17.8   0.1    1.3  1  Hfq       Hfq protein


Domain annotation for each model (and alignments):
>> LSM  LSM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.3   0.1   3.1e-17   2.8e-13       4      66 ..      25      91 ..      22      92 .. 0.87

  Alignments for each domain:
  == domain 1  score: 49.3 bits;  conditional E-value: 3.1e-17
                HHTTTSEEEEEETTSEEEEEEEEEEETTSEEEEEEEEEEETTET....EEEEEEEEEEEGGGEEEEE CS
         LSM  4 kklinkkvtvelkngrelrGtLkgfDqfmNlvLedveetlkdkk....ekrklglvliRGnnivlis 66
                ++     +++  +   +++G+++gfD+fmNlv +d++e++  +k    + r+lg++l++G+n+ li+
  EEA21115.1 25 QQRSTVSIWLYEQLSFRIEGKIRGFDEFMNLVVDDAVEVRLATKseeeKRRNLGQILLKGDNVSLIQ 91
                55556667777788889*********************9988889999***************9996 PP

>> Hfq  Hfq protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.1   2.1e-07    0.0019       8      43 ..      22      59 ..      18      68 .. 0.81

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 2.1e-07
                HHHHCT-EEEEEETT..S-EEEEEEEEE-SSEEEEEET CS
         Hfq  8 qlrkekipvtifLvn..GiklkGviksfDnftvlLesd 43
                +l +++++v+i+L     ++++G+i++fD+f+ l+ +d
  EEA21115.1 22 KLLQQRSTVSIWLYEqlSFRIEGKIRGFDEFMNLVVDD 59
                5678899999999874579************9887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (94 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       391  (0.0218082); expected 358.6 (0.02)
Passed bias filter:                      318  (0.0177366); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.39u 0.26s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 675.39
//
Query:       EEA21116.1  [L=971]
Description: mRNA transport regulator (Mtr10), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.3e-28   98.6   0.2    3.4e-27   95.3   0.1    2.7  2  Xpo1      Exportin 1-like protein
    2.4e-06   27.4   0.0    1.1e-05   25.3   0.0    2.1  2  IBN_N     Importin-beta N-terminal domain
  ------ inclusion threshold ------
      0.056   14.0   0.8        6.8    7.3   0.0    4.5  5  HEAT_EZ   HEAT-like repeat
       0.07   13.1   3.4        0.3   11.0   0.1    2.9  3  TerB      Tellurite resistance protein TerB
       0.49   10.7   4.5        1.7    9.0   0.0    3.5  4  GAT       GAT domain


Domain annotation for each model (and alignments):
>> Xpo1  Exportin 1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.3   0.1   9.5e-31   3.4e-27       1     149 []     105     246 ..     105     246 .. 0.97
   2 ?   -0.5   0.0      0.33   1.2e+03       8      34 ..     747     773 ..     730     791 .. 0.67

  Alignments for each domain:
  == domain 1  score: 95.3 bits;  conditional E-value: 9.5e-31
                 THHHHHHHHHHHHHHHHHHTTTTSTTHHHHHHHHHCT.HHHHHHHHHHHHHHHHHHHTSHTTTSCHHH.HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC CS
        Xpo1   1 pkflrnklaealaelflqeypnnWpsffddllsllssspsglelllriLkvlpeEiadfsrskleqer.rndlkdllrsnvqkilelllqileqsqskk 98 
                 p+ ++++l++ la+l++q+   +W++++ ++ s l s++   +++l++Lk+lpeE+++ ++ +l++++ + ++k+ll++n+++++ ll+q+ ++s +  
  EEA21116.1 105 PRPIQTQLCVGLANLAIQM--TSWKDVLATVGSTLGSNAG--DCVLEFLKILPEEVTEGRKINLSEDElAARTKELLDDNAEQVMHLLTQYSQSSAT-- 197
                 5789***************..****************777..66************************************************99998.. PP

                 HHHHHHHHHHHHHHHHTTTS-HHHHHTSCHHHHHHHHCCSCCCHHHHHHHH CS
        Xpo1  99 qsselveavLkclsswvswidiglivnnpllnllfqlLsdpelreaavecL 149
                   + ++   ++c++sw+++i+ ++iv++pll++++++L+++ +++aav+c+
  EEA21116.1 198 --AATNPRLIDCITSWLREIPATQIVESPLLDVILKALDNDASFDAAVDCI 246
                 ..899*********************************************7 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.33
                 HHHHHHHHHHHHTTTTSTTHHHHHHHH CS
        Xpo1   8 laealaelflqeypnnWpsffddllsl 34 
                  ++a+ +++  + p++ p++++d+++l
  EEA21116.1 747 QSLAFLRILNELPPEQLPDVIEDFFRL 773
                 345555555555566666666666655 PP

>> IBN_N  Importin-beta N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.3   0.0   2.9e-09   1.1e-05       1      72 [.      33      98 ..      33     100 .. 0.96
   2 ?   -2.5   0.0       1.4     5e+03      24      42 ..     484     501 ..     470     513 .. 0.74

  Alignments for each domain:
  == domain 1  score: 25.3 bits;  conditional E-value: 2.9e-09
                HHHHHHHHHCSTCHHHHHHHHHHCTTSHHHHHHHHHHHHHHHHHHHGGSCCCHCGSXHHHHHHHHHHHHHHH CS
       IBN_N  1 AekqLkqlekqpgflsallqilanseselevRqlAalyLknlitkhWsdeeekqslpseekeqIrnnllnll 72
                A++ L++++k+ +++ a    l++ e ++e++++Aa++Lk +it+         +lp++   ++r++ ln l
  EEA21116.1 33 AHEYLENFQKSVEAWTATHAMLQTPEIPIEAKLFAATTLKGKITYDLD------QLPPDAVPSLRDSMLNQL 98
                7899******************************************99......*************99976 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 1.4
                 CTTSHHHHHHHHHHHHHHH CS
       IBN_N  24 nseselevRqlAalyLknl 42 
                   ++e  vR++A+  L ++
  EEA21116.1 484 IPDHE-KVRFSAIMALGRY 501
                 36778.9999999988766 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       2.6   9.5e+03      21      40 ..      78      92 ..      67     107 .. 0.76
   2 ?   -2.8   0.0       2.7   9.7e+03      13      34 ..     166     189 ..     163     190 .. 0.78
   3 ?   -1.7   0.0       1.3   4.7e+03      10      34 ..     461     482 ..     458     483 .. 0.53
   4 ?    7.3   0.0    0.0019       6.8       2      51 ..     489     537 ..     488     541 .. 0.77
   5 ?    1.0   0.0      0.17   6.2e+02      22      53 ..     595     627 ..     577     629 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 2.6
     HEAT_EZ 21 llqplvpeilpaLlalLndd 40
                +l +l p+++p L      d
  EEA21116.1 78 DLDQLPPDAVPSLR-----D 92
                67788899999988.....4 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 2.7
     HEAT_EZ  13 r..laggepellqplvpeilpaLl 34 
                 +  la+  +ell ++ ++++ +L 
  EEA21116.1 166 EdeLAARTKELLDDNAEQVMHLLT 189
                 455778889999999999999886 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 1.3
     HEAT_EZ  10 aLGr.laggepellqplvpeilpaLl 34 
                 a+Gr +    +   ++++p+++p+ +
  EEA21116.1 461 AMGRmV----DSEESTVLPQVIPLIV 482
                 667533....3334555666666554 PP

  == domain 4  score: 7.3 bits;  conditional E-value: 0.0019
     HEAT_EZ   2 rvRraAawaLGr....laggepellqplvpeilpaLlalLnddsdeVRaaAaga 51 
                  vR++A++aLGr     a + pe+l+ ++  ++  +     + s+eV +aAa a
  EEA21116.1 489 KVRFSAIMALGRytewTA-NHPETLEAQLNYVISGFQ----HTSQEVIGAAALA 537
                 59**********999977.789999988888888887....4444666666655 PP

  == domain 5  score: 1.0 bits;  conditional E-value: 0.17
     HEAT_EZ  22 lqplvpeilpaLlalLnddsdeV.RaaAagaLg 53 
                 ++++ + i++  ++l n+ +de  + a+a +L 
  EEA21116.1 595 MKLFCDPIMARIMNLANNAQDEQgQRAVADHLQ 627
                 7889999****************9999999986 PP

>> TerB  Tellurite resistance protein TerB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.1   8.5e-05       0.3      31      66 ..      12      46 ..       7      56 .. 0.88
   2 ?   -2.8   0.1       1.5   5.4e+03      57      81 ..     171     195 ..     166     200 .. 0.74
   3 ?    1.4   0.0     0.079   2.8e+02      51      85 ..     750     781 ..     732     782 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 8.5e-05
        TerB 31 aallaevakaDgqvsesErqafrellksrfglspee 66
                aa+la va + g+vs+sE+++ +e+l ++f+ s+e+
  EEA21116.1 12 AAVLAAVATMQGNVSRSEKAQAHEYL-ENFQKSVEA 46
                89************************.999877665 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1.5
        TerB  57 ksrfglspeeakallelfeeaeeea 81 
                 +++ +l +++a+++++l  ++++++
  EEA21116.1 171 ARTKELLDDNAEQVMHLLTQYSQSS 195
                 5566777899999999999888875 PP

  == domain 3  score: 1.4 bits;  conditional E-value: 0.079
        TerB  51 afrellksrfglspeeakallelfeeaeeeavdle 85 
                 af ++l    +l+pe++++++e f ++ ++a+ ++
  EEA21116.1 750 AFLRIL---NELPPEQLPDVIEDFFRLASDAIRFY 781
                 444555...78899999999999988888887665 PP

>> GAT  GAT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.1       3.7   1.3e+04      36      49 ..     180     193 ..     161     199 .. 0.55
   2 ?    9.0   0.0   0.00048       1.7      20      49 ..     257     285 ..     245     295 .. 0.83
   3 ?   -1.4   0.1      0.82     3e+03      36      50 ..     426     440 ..     420     446 .. 0.63
   4 ?    0.8   0.1      0.18   6.4e+02      33      60 ..     599     628 ..     588     630 .. 0.81

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 3.7
         GAT  36 mqpriqklieetad 49 
                   +++++l++++++
  EEA21116.1 180 NAEQVMHLLTQYSQ 193
                 33455555555544 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00048
         GAT  20 llenellkeLyetckamqpriqklieetad 49 
                 ++++ +++ Ly ++ a++p++q+l+e+ +d
  EEA21116.1 257 DDSMSAIQRLYPRIVALRPKLQELAEA-ED 285
                 457899*******************99.43 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.82
         GAT  36 mqpriqklieetade 50 
                 + ++iq++++++a +
  EEA21116.1 426 AYQQIQQWVSKYASQ 440
                 556777777776543 PP

  == domain 4  score: 0.8 bits;  conditional E-value: 0.18
         GAT  33 ckamqpriqklieetadeed..llaelLql 60 
                 c  +  ri++l+++ +de+   ++a+ Lql
  EEA21116.1 599 CDPIMARIMNLANNAQDEQGqrAVADHLQL 628
                 777889********8888877888888875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (971 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       695  (0.038764); expected 358.6 (0.02)
Passed bias filter:                      631  (0.0351944); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.77u 0.28s 00:00:01.05 Elapsed: 00:00:00.43
# Mc/sec: 6712.85
//
Query:       EEA21117.1  [L=936]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.8e-61  205.4   0.0    1.2e-60  204.8   0.0    1.3  1  Fungal_trans  Fungal specific transcription factor domain
    8.1e-05   22.9  15.0     0.0063   16.9   4.1    2.9  2  zf-C2H2       Zinc finger, C2H2 type
  ------ inclusion threshold ------
          4    8.0  10.8       0.91   10.1   3.1    2.7  2  zf-H2C2_2     Zinc-finger double domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  204.8   0.0   2.1e-64   1.2e-60       2     266 ..     402     697 ..     401     698 .. 0.98

  Alignments for each domain:
  == domain 1  score: 204.8 bits;  conditional E-value: 2.1e-64
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLl 98 
                    +++ +fh q+pilh+p+f  +           +++llll+ +a+Ga  +e  ++++  +   e ++f+a+++r+ei+ + d+++p++ lw+ q+Ll
    EEA21117.1 402 GSYWLHFHAQLPILHRPTFVADR----------TPSLLLLSLMAIGAATLERMHGQTVIDGAAELANFLAWHIRWEIFMDVDCRPPAK-LWVFQALL 487
                   58*********************..........************************99999999***********************.******** PP

  Fungal_trans  99 llelyektssdralher...hhgvavr.larslgLhrnpsyvgkks....................lwklweeeaesrrRlwwaaFylDktialklG 171
                   lle+yek++s+ralher   hh ++++ ++r  ++ ++++y  + s                     w +w+   e+ rR++++aF++D ++a+++G
    EEA21117.1 488 LLEIYEKGYSTRALHERahiHHDTTLTlMRRGSSFLGRSAYDTPASfrderanrsvttttdgeredPWSYWIR-TEATRRVAFGAFVMDSIHATMFG 583
                   *******************************************999***************************.*********************** PP

  Fungal_trans 172 rppllddsqinlpLPcddddlwesddaseetlvetklsneeksrkiasfllaLkkilsk............iagsllsiekqlqqrdlq........ 248
                   + + + +++++lpLPcd+  lw++ +a+e+ +++t+   +++++k++ fl  Lkk l +            ++g lls++++++qrdlq        
    EEA21117.1 584 HSVKMVAHELRLPLPCDEA-LWSAGSAAEVSRMQTV--LQSNGVKPTMFLDGLKKTLTGqkvrtnafgrmiLMGGLLSVSWHMNQRDLQvsslgvtq 677
                   ***99**************.**************98..9********************************9999********************** PP

  Fungal_trans 249 ..seklswveeleraldnWr 266
                        ++w+  l ra+dnW+
    EEA21117.1 678 vlGGRDKWRSSLLRAFDNWK 697
                   *******************8 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   4.1   1.1e-06    0.0063       1      23 []      30      54 ..      30      54 .. 0.96
   2 !   10.7   3.2   9.9e-05      0.59       1      23 []      60      84 ..      60      84 .. 0.97

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 1.1e-06
                EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCp..dCgksFkrksnLkrHirtH 23
                ++C   +Cgks++r ++L rH+  H
  EEA21117.1 30 FECQheGCGKSYSRAEHLHRHQLNH 54
                89999*****************999 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 9.9e-05
                EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCp..dCgksFkrksnLkrHirtH 23
                y+C+  dC +sF r+++  rH+ +H
  EEA21117.1 60 YRCDfpDCYRSFVRQDLCIRHRERH 84
                99********************999 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   1.0     0.058   3.5e+02      11      25 ..      26      42 ..       9      43 .. 0.74
   2 ?   10.1   3.1   0.00015      0.91       2      25 ..      47      72 ..      46      73 .. 0.88

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.058
   zf-H2C2_2 11 gekpyeCp..lCdkaFk 25
                ++k++eC    C+k+++
  EEA21117.1 26 PDKKFECQheGCGKSYS 42
                5678****977***997 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00015
   zf-H2C2_2  2 LrrHirkHtgekpyeCp..lCdkaFk 25
                L rH+ +Ht++ +y C+   C  +F+
  EEA21117.1 47 LHRHQLNHTPKQIYRCDfpDCYRSFV 72
                669**************877999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (936 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       484  (0.0269954); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.69u 0.26s 00:00:00.95 Elapsed: 00:00:00.43
# Mc/sec: 6481.04
//
Query:       EEA21118.1  [L=139]
Description: cytokinesis EF-hand protein Cdc4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    4.5e-12   46.3   0.6    2.4e-07   31.1   0.1    2.1  2  EF-hand_7  EF-hand domain pair
      4e-10   39.9   0.1    0.00011   22.4   0.0    2.4  2  EF-hand_9  EF-hand domain
    3.8e-09   35.8   1.0     0.0046   16.8   0.0    3.7  4  EF-hand_6  EF-hand domain
    6.6e-09   34.7   0.6      0.017   14.6   0.0    3.8  4  EF-hand_1  EF hand
    3.4e-07   30.0   0.8    0.00032   20.5   0.1    3.2  3  EF-hand_8  EF-hand domain pair


Domain annotation for each model (and alignments):
>> EF-hand_7  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   0.0   1.5e-05     0.055       5      36 ..       7      48 ..       3      64 .. 0.72
   2 !   31.1   0.1   6.6e-11   2.4e-07       5      67 ..      77     133 ..      73     136 .. 0.93

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.5e-05
   EF-hand_7  5 keaFkelDtdgdgyldkeellrllrkifqga..........g 36
                keaF ++D++g+g++  + l +llr+  q+           +
  EEA21118.1  7 KEAFSLFDKRGNGRVALDSLGDLLRACGQNPtlaeirdleaS 48
                899**********************86655555554444443 PP

  == domain 2  score: 31.1 bits;  conditional E-value: 6.6e-11
   EF-hand_7   5 kea.FkelDtdgdgyldkeellrllrkifqgagegsklsdeelellfkefDtdkdGvisfdEFl 67 
                 +++ F+ +D+d +g++ + +l+ +l+        g+k++d+e+++l+k +Dt++ G+i++++++
  EEA21118.1  77 YCRgFQVFDKDLTGFIGVGQLRYILT------NLGEKMTDDEVDELLKVVDTSS-GEINYTDLV 133
                 6888******************9999......89******************98.9****9986 PP

>> EF-hand_9  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.4   0.0   3.1e-08   0.00011       3      61 ..       9      61 ..       7      64 .. 0.81
   2 !   15.0   0.0   6.5e-06     0.023       4      46 ..      81     122 ..      79     135 .. 0.87

  Alignments for each domain:
  == domain 1  score: 22.4 bits;  conditional E-value: 3.1e-08
   EF-hand_9  3 vFevcDtqktGrVpvsrlidyLravtaqdpeeseLeelakelDPdgedasvdldtflrv 61
                 F+++D    GrV++  l d+Lra+++ +p+ +e+ +l +++   g  +  d+d f++v
  EEA21118.1  9 AFSLFDKRGNGRVALDSLGDLLRACGQ-NPTLAEIRDLEASI---G--GDFDFDSFQKV 61
                6**************************.99988888888776...2..24566666666 PP

  == domain 2  score: 15.0 bits;  conditional E-value: 6.5e-06
   EF-hand_9   4 FevcDtqktGrVpvsrlidyLravtaqdpeeseLeelakelDP 46 
                 F+v+D + tG + v +l  +L   ++ + ++ e++el k +D 
  EEA21118.1  81 FQVFDKDLTGFIGVGQLRYILTNLGE-KMTDDEVDELLKVVDT 122
                 9*************************.6667799999999985 PP

>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.0   1.3e-06    0.0046       3      29 ..       7      32 ..       5      34 .. 0.91
   2 ?   -1.2   0.0      0.78   2.8e+03      18      27 ..      54      63 ..      51      67 .. 0.74
   3 !   13.1   0.1     2e-05     0.072       6      31 .]      81     105 ..      78     105 .. 0.94
   4 ?    1.7   0.0     0.087   3.1e+02       4      24 ..     115     134 ..     112     138 .. 0.72

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 1.3e-06
   EF-hand_6  3 reaFklfDkdgdGkidaeElrkalrka 29
                +eaF lfDk g+G +  + l ++lr a
  EEA21118.1  7 KEAFSLFDKRGNGRVALDSLGDLLR-A 32
                89**********************9.6 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.78
   EF-hand_6 18 daeElrkalr 27
                d++ ++k+l+
  EEA21118.1 54 DFDSFQKVLN 63
                7778888886 PP

  == domain 3  score: 13.1 bits;  conditional E-value: 2e-05
   EF-hand_6   6 FklfDkdgdGkidaeElrkalrkalg 31 
                 F+ fDkd +G+i   +lr +l+ +lg
  EEA21118.1  81 FQVFDKDLTGFIGVGQLRYILT-NLG 105
                 99*******************9.776 PP

  == domain 4  score: 1.7 bits;  conditional E-value: 0.087
   EF-hand_6   4 eaFklfDkdgdGkidaeElrk 24 
                 e+ k  D++ +G+i++ +l++
  EEA21118.1 115 ELLKVVDTS-SGEINYTDLVR 134
                 566666775.99999999976 PP

>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   4.8e-06     0.017       3      27 ..       7      31 ..       5      33 .. 0.88
   2 ?   -2.0   0.0      0.97   3.5e+03      18      26 ..      54      62 ..      51      64 .. 0.67
   3 !   12.5   0.0   2.3e-05     0.084       6      28 ..      81     103 ..      76     104 .. 0.90
   4 ?    3.7   0.0     0.014        51       1      24 [.     112     134 ..     112     137 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 4.8e-06
                HHHHHHHTTTSSSEEEHHHHHHHHH CS
   EF-hand_1  3 keiFrefDkDgdGkIdfeEfkellk 27
                ke+F++fDk g+G++ ++ + +ll+
  EEA21118.1  7 KEAFSLFDKRGNGRVALDSLGDLLR 31
                8*************99998888887 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.97
                EHHHHHHHH CS
   EF-hand_1 18 dfeEfkell 26
                df+ f+++l
  EEA21118.1 54 DFDSFQKVL 62
                777777776 PP

  == domain 3  score: 12.5 bits;  conditional E-value: 2.3e-05
                 HHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1   6 FrefDkDgdGkIdfeEfkellkk 28 
                 F++fDkD +G+I   +++ +l+ 
  EEA21118.1  81 FQVFDKDLTGFIGVGQLRYILTN 103
                 9*****************99986 PP

  == domain 4  score: 3.7 bits;  conditional E-value: 0.014
                 HHHHHHHHHTTTSSSEEEHHHHHH CS
   EF-hand_1   1 elkeiFrefDkDgdGkIdfeEfke 24 
                 e++e+ +++D   +G I++ ++++
  EEA21118.1 112 EVDELLKVVD-TSSGEINYTDLVR 134
                 6788888888.88999*9999986 PP

>> EF-hand_8  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.0     0.012        41      32      47 ..      10      25 ..       7      33 .. 0.84
   2 ?    2.7   0.0     0.031   1.1e+02       2      17 ..      50      66 ..      50      90 .. 0.63
   3 !   20.5   0.1   8.8e-08   0.00032       2      47 ..      89     131 ..      88     135 .. 0.87

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.012
   EF-hand_8 32 frefDtdgdGkisfeE 47
                f++fD  g+G++ +++
  EEA21118.1 10 FSLFDKRGNGRVALDS 25
                99*********98886 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.031
   EF-hand_8  2 kgkItreelrril.ril 17
                +g  +++++++ l r  
  EEA21118.1 50 GGDFDFDSFQKVLnRPG 66
                5889*******664443 PP

  == domain 3  score: 20.5 bits;  conditional E-value: 8.8e-08
   EF-hand_8   2 kgkItreelrrilrilglkkglseeevdilfrefDtdgdGkisfeE 47 
                 +g I +  lr il+ lg k  ++++evd+l++ +Dt  +G i++++
  EEA21118.1  89 TGFIGVGQLRYILTNLGEK--MTDDEVDELLKVVDTS-SGEINYTD 131
                 699**********999*99..**************96.56666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (139 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       343  (0.019131); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1014.96
//
Query:       EEA21119.1  [L=144]
Description: cytokinesis EF-hand protein Cdc4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    5.1e-12   46.1   0.6    2.6e-07   31.0   0.1    2.1  2  EF-hand_7  EF-hand domain pair
    4.6e-10   39.7   0.1    0.00012   22.3   0.0    2.4  2  EF-hand_9  EF-hand domain
    4.5e-09   35.5   1.0     0.0049   16.7   0.0    3.7  4  EF-hand_6  EF-hand domain
    7.9e-09   34.4   0.5      0.018   14.5   0.0    3.8  4  EF-hand_1  EF hand
    4.2e-07   29.7   0.8    0.00034   20.4   0.1    3.2  3  EF-hand_8  EF-hand domain pair


Domain annotation for each model (and alignments):
>> EF-hand_7  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.8   0.0   1.7e-05     0.059       5      36 ..      12      53 ..       8      69 .. 0.72
   2 !   31.0   0.1   7.1e-11   2.6e-07       5      67 ..      82     138 ..      78     141 .. 0.93

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.7e-05
   EF-hand_7  5 keaFkelDtdgdgyldkeellrllrkifqga..........g 36
                keaF ++D++g+g++  + l +llr+  q+           +
  EEA21119.1 12 KEAFSLFDKRGNGRVALDSLGDLLRACGQNPtlaeirdleaS 53
                899**********************86655555554444443 PP

  == domain 2  score: 31.0 bits;  conditional E-value: 7.1e-11
   EF-hand_7   5 kea.FkelDtdgdgyldkeellrllrkifqgagegsklsdeelellfkefDtdkdGvisfdEFl 67 
                 +++ F+ +D+d +g++ + +l+ +l+        g+k++d+e+++l+k +Dt++ G+i++++++
  EEA21119.1  82 YCRgFQVFDKDLTGFIGVGQLRYILT------NLGEKMTDDEVDELLKVVDTSS-GEINYTDLV 138
                 6888******************9999......89******************98.9****9986 PP

>> EF-hand_9  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.3   0.0   3.3e-08   0.00012       3      61 ..      14      66 ..      12      69 .. 0.81
   2 !   14.9   0.0     7e-06     0.025       4      46 ..      86     127 ..      84     140 .. 0.87

  Alignments for each domain:
  == domain 1  score: 22.3 bits;  conditional E-value: 3.3e-08
   EF-hand_9  3 vFevcDtqktGrVpvsrlidyLravtaqdpeeseLeelakelDPdgedasvdldtflrv 61
                 F+++D    GrV++  l d+Lra+++ +p+ +e+ +l +++   g  +  d+d f++v
  EEA21119.1 14 AFSLFDKRGNGRVALDSLGDLLRACGQ-NPTLAEIRDLEASI---G--GDFDFDSFQKV 66
                6**************************.99988888888776...2..24566666666 PP

  == domain 2  score: 14.9 bits;  conditional E-value: 7e-06
   EF-hand_9   4 FevcDtqktGrVpvsrlidyLravtaqdpeeseLeelakelDP 46 
                 F+v+D + tG + v +l  +L   ++ + ++ e++el k +D 
  EEA21119.1  86 FQVFDKDLTGFIGVGQLRYILTNLGE-KMTDDEVDELLKVVDT 127
                 9*************************.6667799999999985 PP

>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   1.4e-06    0.0049       3      29 ..      12      37 ..      10      39 .. 0.91
   2 ?   -1.3   0.0      0.82   2.9e+03      18      27 ..      59      68 ..      56      72 .. 0.74
   3 !   13.0   0.1   2.1e-05     0.077       6      31 .]      86     110 ..      83     110 .. 0.94
   4 ?    1.7   0.0     0.092   3.3e+02       4      24 ..     120     139 ..     117     143 .. 0.72

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 1.4e-06
   EF-hand_6  3 reaFklfDkdgdGkidaeElrkalrka 29
                +eaF lfDk g+G +  + l ++lr a
  EEA21119.1 12 KEAFSLFDKRGNGRVALDSLGDLLR-A 37
                89**********************9.6 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.82
   EF-hand_6 18 daeElrkalr 27
                d++ ++k+l+
  EEA21119.1 59 DFDSFQKVLN 68
                7778888886 PP

  == domain 3  score: 13.0 bits;  conditional E-value: 2.1e-05
   EF-hand_6   6 FklfDkdgdGkidaeElrkalrkalg 31 
                 F+ fDkd +G+i   +lr +l+ +lg
  EEA21119.1  86 FQVFDKDLTGFIGVGQLRYILT-NLG 110
                 99*******************9.776 PP

  == domain 4  score: 1.7 bits;  conditional E-value: 0.092
   EF-hand_6   4 eaFklfDkdgdGkidaeElrk 24 
                 e+ k  D++ +G+i++ +l++
  EEA21119.1 120 ELLKVVDTS-SGEINYTDLVR 139
                 566666775.99999999976 PP

>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.0   5.1e-06     0.018       3      27 ..      12      36 ..      10      38 .. 0.88
   2 ?   -2.1   0.0         1   3.6e+03      18      26 ..      59      67 ..      56      69 .. 0.67
   3 !   12.4   0.0   2.5e-05     0.089       6      28 ..      86     108 ..      81     109 .. 0.90
   4 ?    3.7   0.0     0.015        54       1      24 [.     117     139 ..     117     142 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 5.1e-06
                HHHHHHHTTTSSSEEEHHHHHHHHH CS
   EF-hand_1  3 keiFrefDkDgdGkIdfeEfkellk 27
                ke+F++fDk g+G++ ++ + +ll+
  EEA21119.1 12 KEAFSLFDKRGNGRVALDSLGDLLR 36
                8*************99998888887 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1
                EHHHHHHHH CS
   EF-hand_1 18 dfeEfkell 26
                df+ f+++l
  EEA21119.1 59 DFDSFQKVL 67
                777777776 PP

  == domain 3  score: 12.4 bits;  conditional E-value: 2.5e-05
                 HHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1   6 FrefDkDgdGkIdfeEfkellkk 28 
                 F++fDkD +G+I   +++ +l+ 
  EEA21119.1  86 FQVFDKDLTGFIGVGQLRYILTN 108
                 9*****************99986 PP

  == domain 4  score: 3.7 bits;  conditional E-value: 0.015
                 HHHHHHHHHTTTSSSEEEHHHHHH CS
   EF-hand_1   1 elkeiFrefDkDgdGkIdfeEfke 24 
                 e++e+ +++D   +G I++ ++++
  EEA21119.1 117 EVDELLKVVD-TSSGEINYTDLVR 139
                 6788888888.8899999999986 PP

>> EF-hand_8  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0     0.012        44      32      47 ..      15      30 ..      12      38 .. 0.84
   2 ?    2.6   0.0     0.033   1.2e+02       2      17 ..      55      71 ..      55      95 .. 0.63
   3 !   20.4   0.1   9.5e-08   0.00034       2      47 ..      94     136 ..      93     140 .. 0.87

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.012
   EF-hand_8 32 frefDtdgdGkisfeE 47
                f++fD  g+G++ +++
  EEA21119.1 15 FSLFDKRGNGRVALDS 30
                99*********98886 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.033
   EF-hand_8  2 kgkItreelrril.ril 17
                +g  +++++++ l r  
  EEA21119.1 55 GGDFDFDSFQKVLnRPG 71
                5889*******664443 PP

  == domain 3  score: 20.4 bits;  conditional E-value: 9.5e-08
   EF-hand_8   2 kgkItreelrrilrilglkkglseeevdilfrefDtdgdGkisfeE 47 
                 +g I +  lr il+ lg k  ++++evd+l++ +Dt  +G i++++
  EEA21119.1  94 TGFIGVGQLRYILTNLGEK--MTDDEVDELLKVVDTS-SGEINYTD 136
                 699**********999*99..**************96.56666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (144 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       371  (0.0206927); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.46u 0.30s 00:00:00.76 Elapsed: 00:00:00.50
# Mc/sec: 860.29
//
Query:       EEA21120.1  [L=270]
Description: hypothetical protein PMAA_049220 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (270 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       580  (0.0323498); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.67u 0.34s 00:00:01.01 Elapsed: 00:00:00.59
# Mc/sec: 1377.58
//
Query:       EEA21121.1  [L=717]
Description: metallopeptidase MepB [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   1.3e-158  529.1   0.0   1.7e-158  528.7   0.0    1.1  1  Peptidase_M3  Peptidase family M3


Domain annotation for each model (and alignments):
>> Peptidase_M3  Peptidase family M3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  528.7   0.0  9.3e-163  1.7e-158       2     457 ..     221     715 ..     220     716 .. 0.98

  Alignments for each domain:
  == domain 1  score: 528.7 bits;  conditional E-value: 9.3e-163
                   HHC-S-HHHHHHHHHHHCTTTCCSS..THHHHHHHHHHHHHHHHHHHTT-SSHHHHHHTTSTT-SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Peptidase_M3   2 lkespdrelRkeayeashskaaeqrntlensklleellklraelAkllgyesyaelaledkmaknpetvldfleelvkklrpllekelkllkelkkk 98 
                   lk+++++e+Rk++ + + +k++       n++l++e++ lr+e A+llgy+++a++++edkmak+p+tv++fl +l+++l+  + ke+++lkelkk+
    EEA21121.1 221 LKYAKNAETRKRVSIGNENKCN------SNVPLFKEAMVLRDEAARLLGYPNHAAFRIEDKMAKTPQTVDTFLGDLRSRLTAGGLKEIEKLKELKKA 311
                   89******************99......67******************************************************************* PP

                   C...CT-S..SS--CCCHHHHHHHHHCCCCS--CCCCGGG-BHHHHHHCHHHHHHHHHTEEEEEETTS.............--SSTT-EEEEEEET. CS
  Peptidase_M3  99 e...lgle..gelqpwDvaYYsekqreekydldqeelkeyfpletvleGllelfeeLfGikfveekdak...........gevwhedVrkleVvde. 178
                   +   +g++  g +  wD+++Y++ ++e++y+ld ++++e+fpl+t++ G+le+feeLfG+ fve+k+++           + vwhedV++++V+d+ 
    EEA21121.1 312 DvesRGEKfdGHYFLWDHRFYDRLMLEKEYQLDHQKISEFFPLQTTVRGMLEIFEELFGLVFVEVKGDDrasisptgkgeDIVWHEDVQLFSVWDDe 408
                   99997766789************************************************************************************98 PP

                   .TT-EEEEEEEEEEC--TTS-SS-EEEEEE--B..TTS-B--EEEEEEEEE---BTTS--B--HHHHHHHHHHHHHHHHHHC--BSSGGGSTT-S-C CS
  Peptidase_M3 179 ilsegligeiylDlyerkgKrggAasfglvksr..edgtrqlpviylllNftkpsskkPsLLtldevetLfHEfGHsmHsllsrteysnvsgtnvpi 273
                      +g++g++ylDl++r+gK+g+Aa+f+l++++  ++g+ ++p+++l++Nf+kp++kkPsLL++dev tLfHE+GH++H+l+++t ys+++gtn+ +
    EEA21121.1 409 AQGSGFVGYLYLDLHPREGKYGHAANFNLQPGFieSNGNKRYPATALVCNFSKPTEKKPSLLKHDEVVTLFHELGHGIHDLVAKTIYSRFHGTNTVR 505
                   999*****************************98669************************************************************ PP

                   CCCCHHHHHHHHGGGSHHHHHCC-B-TTT--B....................--HHHHHHHHCCCCTTHHHHHHHHHHHHHHHHHCTT-TCCGHH.. CS
  Peptidase_M3 274 dfvElpSqlmEnlltepevlkslskhyetgea....................ipeelleklikaknvnaalellrqlvfaafdqelHeeaeeeqilk 350
                   dfvE+pSq++En++++p++lksls+hy+t++                     ip++++e+li++k+vn+al++lrql+f+ fd+++He  ++++i +
    EEA21121.1 506 DFVEAPSQMLENWCWTPSQLKSLSRHYSTLSEdyrkaweessstpgtpaperIPDDVIESLIRTKHVNDALFNLRQLHFGIFDMTMHEPSSHDEIVS 602
                   ************************************************************************************************* PP

                   ..HHHHHHHHHHCTTSCTTBT.......TSSGGGC-CCCHTSS-TTTTCHHHHHHHHHHHHHHCCHHCCTT-CCHHHHHHHHTTTTTTSS-HHHHHH CS
  Peptidase_M3 351 kdlletyaelrkkflglpvap.......deasqasFghlfahgYaanYYsylyaevlaldifekffeedplnretGeryrkeiLsrGgskdplellk 440
                    + + ty+ lrk++++++ ++       + + qa+Fghl+ +gY+a+YY+yl ++v+++d+f+++f+e+p+++e G+ryr+++L++Ggs+d+++ l+
    EEA21121.1 603 LNPTVTYNTLRKEISQIEGPEvlgqgdeWGNGQATFGHLM-GGYDAGYYGYLSSQVYSTDMFYTIFKENPMDPEQGRRYRRTVLEKGGSQDEMKSLT 698
                   99**************99999999999999*********7.******************************************************** PP

                   CCCSS---SHHHHHHCT CS
  Peptidase_M3 441 kflgrepsadallkalg 457
                   +flgrep+++a++k lg
    EEA21121.1 699 EFLGREPKTEAFYKDLG 715
                   *************9887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (717 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       523  (0.0291706); expected 358.6 (0.02)
Passed bias filter:                      470  (0.0262145); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.75u 0.34s 00:00:01.09 Elapsed: 00:00:00.54
# Mc/sec: 3992.51
//
Query:       EEA21122.1  [L=458]
Description: stearic acid desaturase (SdeA), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.7e-19   70.0  15.2    4.4e-19   69.3  15.2    1.3  1  FA_desaturase  Fatty acid desaturase
      1e-16   60.8   0.1    2.5e-16   59.6   0.1    1.7  1  Cyt-b5         Cytochrome b5-like Heme/Steroid binding domain
  ------ inclusion threshold ------
        0.1   12.1   0.5       0.27   10.8   0.3    1.7  2  DUF1189        Protein of unknown function (DUF1189)


Domain annotation for each model (and alignments):
>> FA_desaturase  Fatty acid desaturase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.3  15.2   7.3e-23   4.4e-19       6     251 ..      66     294 ..      61     297 .. 0.75

  Alignments for each domain:
  == domain 1  score: 69.3 bits;  conditional E-value: 7.3e-23
  FA_desaturase   6 lllalllglf.llgitgslaHeaaHgalfkkrklnrwlndllgallglplgisysawrisHlrHHaytngpdeDpdlaplalsrfeglfryllrll 100
                    ++  +l+ +   lgit+++++ +aH +++     +  l+ +l+a+ g ++  s+ +w + H+ HH+y  ++d+Dp+      s ++gl + +l+++
     EEA21122.1  66 WA--VLYYFYtGLGITAGYHRLWAHCSYS----ATLPLQIFLAAAGGGAVEGSIRWWARGHRAHHRY-TDTDKDPY------SVRKGLLYSHLGWM 148
                    22..3333433378889********8888....5666666777779999999***************.6666****......6699999999**** PP

  FA_desaturase 101 lgllvlgwllalvlglwlrrlarrrapsksrrrkwrllawlllllawlglwlalllllglalllwlvplllllfllalvl.nyveHyggdwgerqv 195
                     + ++++       + ++ + + +++p+ ++++++++  ++++ l++  ++++l++  ++++++++  l+++++  a++  n + H+    g++++
     EEA21122.1 149 VMKQNPK------RIGRTDITDLNEDPIVKFQHRHYIKIVAFMGLVFPMMVAGLGWGDWWGGFVYAGILRIFFVQQATFCvNSLAHWL---GDQPF 235
                    *****99......333788888888888888886666666666666666666666666666546666666666655555478888864...55555 PP

  FA_desaturase 196 etsasirsaswllnlltgnlnyHieHHlfP.....gvpwyrLpelhrrlrellpehglpyr 251
                     +++s r ++ + +l+t++ +yH+ HH fP     ++ w++++  ++    ++++ gl+y+
     EEA21122.1 236 DDRNSPR-DHVITALITLGEGYHNFHHEFPsdyrnAIEWHQYDPTKW-FIWTCKQLGLAYD 294
                    5555555.***********************************9996.6666888888875 PP

>> Cyt-b5  Cytochrome b5-like Heme/Steroid binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.6   0.1   4.1e-20   2.5e-16       4      73 ..     338     408 ..     335     409 .. 0.91

  Alignments for each domain:
  == domain 1  score: 59.6 bits;  conditional E-value: 4.1e-20
                 HHTTTECTTEEEEEETTEEEECTTTCCCSTTCSHHHHTTTTSBBHHHHHHTT..GGCHHHHHHHHGGEEEEE CS
      Cyt-b5   4 elskhngkndlwvairgkVYDvskflskhpGgesailkyaGkDateafksvv..hsekdaekllkkylvGkl 73 
                 +  +++++++ ++ai g ++Dv++f+++hpGg+++i++  GkDat+ f+  v  hs++ a++ll +++vG++
  EEA21122.1 338 DYVEQAKNGRGLIAIAGVIHDVTDFIKDHPGGRAMINSGIGKDATAMFNGGVyfHSNA-AHNLLSTMRVGVI 408
                 55667788899******************************************88877.9**********87 PP

>> DUF1189  Protein of unknown function (DUF1189)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.3   4.5e-05      0.27     140     216 ..      25     101 ..      15     104 .. 0.76
   2 ?   -3.3   0.0       0.9   5.4e+03     138     165 ..     165     189 ..     148     214 .. 0.53

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 4.5e-05
     DUF1189 140 kedlreflssvksilkiilvlilivlflvsllltl.....idalilaliglilarilkiklsYkqlfkisvyalTlPtilna 216
                 k +l+++     +   ++ v ++i + l+ ++  l     +++++ a++ ++++ + +i+  Y+ l+  + y+ TlP+ +++
  EEA21122.1  25 KMTLKNWY----KHVDWLNVYFIIGIPLYGCIQSLwvplqLKTAVWAVLYYFYTGL-GITAGYHRLWAHCSYSATLPLQIFL 101
                 55566666....55666666666666666666666555578889999999999885.********************97775 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 0.9
     DUF1189 138 ltkedlreflssvksilkiilvlilivl 165
                 l+++ +++f       ++ i++++ +v 
  EEA21122.1 165 LNEDPIVKFQ---HRHYIKIVAFMGLVF 189
                 5555555555...333333333333332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (458 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       524  (0.0292264); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 3181.73
//
Query:       EEA21123.1  [L=958]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.2e-21   77.3   0.0    7.6e-21   74.7   0.0    2.1  1  Pkinase      Protein kinase domain
      1e-15   57.8   0.0    9.7e-11   41.4   0.0    2.3  2  Pkinase_Tyr  Protein tyrosine kinase
  ------ inclusion threshold ------
       0.44   10.1   2.0       0.61    9.7   0.9    1.7  2  BAR          BAR domain


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.7   0.0   1.3e-24   7.6e-21       2     190 ..     175     429 ..     174     434 .. 0.80

  Alignments for each domain:
  == domain 1  score: 74.7 bits;  conditional E-value: 1.3e-24
                 EEEEEEEEESSEEEEEEE.............ETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHS.CTTB--EEEEEEESSEEE.EEEE--TTEBH CS
     Pkinase   2 ekleklGeGsfGkVykav.............eketgkivAvKkikkekakkkkekkvlrEikilkklk.hpnivrlyevfeekdely.lvleyveggel 85 
                  ++e+lG+GsfGkV+k++              ++t   vA K   +  + + ++++ ++E  +  +++ ++ni+  y++++  ++ y l++ ++   +l
  EEA21123.1 175 LEEEELGSGSFGKVFKVKiakghfkdtrhgtLNATIMDVARKDYITTTQFDGEKERNMMERILTGSTRkCENILGNYGSLRIGTNAYsLFMPCAI-CDL 272
                 57899*********9986222222111111123445679999999999999998999999999988888*************9998845555555.558 PP

                 HHHHH......HHSS--HHHHHHHHHHHHHHHHHHHHTT.........EE-SS-SGGGEEEETTTE........EEE-SGTTSEESSSSCS........ CS
     Pkinase  86 adlle......rkgslseeeakkiakqilegleylHskg.........iiHrDlKpeNiLidekge........lKitDFGlakelesssk........ 153
                  d+++       +++ +++++   ak ++egl++lH++          + H+DlKp+NiLi ++           K++DFG+a+   ++          
  EEA21123.1 273 SDYMTkhhptrPSSVHEKAQIVLSAKGLAEGLDFLHNEMkgpdqqdmvCYHMDLKPSNILIFRDTAydggtrfvWKLSDFGMARVKYRRRGqtvereem 371
                 888876667633444566689999************776699999*9999***********96554588889999*********8877766799***** PP

                 ....................BCTTTSCGGGS-HHHH.TTSCBSHHHHHHHHHHHHHHH CS
     Pkinase 154 ....................ltsfvgtseYlAPEvl.keneyskkvDvWslGvilyel 190
                                     ++++ g  +Yl+PE l +++ +++++DvW+lG++l  +
  EEA21123.1 372 dfnsaflpriqpeterspsgTRNRRGEGTYLPPESLtSTRTMTTASDVWALGCVLSVV 429
                 ********************99**************555555************9765 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.4   0.0   1.6e-14   9.7e-11       4     164 ..     177     370 ..     175     388 .. 0.80
   2 !   14.0   0.0   3.8e-06     0.023     166     212 ..     396     443 ..     378     456 .. 0.79

  Alignments for each domain:
  == domain 1  score: 41.4 bits;  conditional E-value: 1.6e-14
                  EEEEEEESSEEEEEEEEET.........TTTSSEEEEEEEEE..STTSSHHHHHHHHHHHHHHHTS-BTTB--EEEEEESSSSEEEEEE--TTEBHHH CS
  Pkinase_Tyr   4 gkklGeGafGkVvegtlkg.........ekekkevkVavKtl..keeateeekeelleeakimkklkhpnivkllgvctkeepllivteyvkgGdLlk 90 
                  +++lG+G+fGkV++ ++ +         + + + ++Va K    + + + e++++++e + + ++ k +ni+  +g    + + + ++  ++  dL++
   EEA21123.1 177 EEELGSGSFGKVFKVKIAKghfkdtrhgTLNATIMDVARKDYitTTQFDGEKERNMMERILTGSTRKCENILGNYGSLRIGTNAYSLFMPCAICDLSD 274
                  589***********9998889988877666778899999977435566667777888877777777*************99999999999******** PP

                  HHHHT....CTTTSBHHHHHHHHHHHHHHHHHHHHTT.........EEEST-SGGGEEEEE........TTEEEE-STTTHEETTTSSEE.EETTS CS
  Pkinase_Tyr  91 fLrkk....ekekltlkdllsfalqvAkGmeyLeskk.........lvHrdlaarNvLlse........nkvvkisDfGLardiekddey.vkkee 164
                  +++k+     ++  +  +++  a  +A+G+++L+++          + H dl   N+L+ +        + v k+sDfG+ar  +++  + v++ee
   EEA21123.1 275 YMTKHhptrPSSVHEKAQIVLSAKGLAEGLDFLHNEMkgpdqqdmvCYHMDLKPSNILIFRdtaydggtRFVWKLSDFGMARVKYRRRGQtVEREE 370
                  ****976654555566677888899********975444555566699***********99999999967789*********99765544144444 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 3.8e-06
                  TSGGGGS-HHHHHHSE.EEHHHHHHHHHHHHHHHHTTSSGTTTTSHHH CS
  Pkinase_Tyr 166 klpvkWmapEslkekk.ftsksDvWsfGvllwEiftlgespypglkne 212
                  +    +++pEsl++++ +t++sDvW+ G +l  +f + e+  +g++n 
   EEA21123.1 396 RGEGTYLPPESLTSTRtMTTASDVWALGCVLSVVFAYLEDGGEGVENY 443
                  5566799****9876659*************99998877766666665 PP

>> BAR  BAR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0      0.65   3.9e+03      97     131 ..     214     248 ..     192     251 .. 0.73
   2 ?    9.7   0.9    0.0001      0.61     114     168 ..     473     527 ..     468     536 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 0.65
         BAR  97 alekygeavkklaqteeelekrvetnfldplrell 131
                 a ++y  + +  +++e+++++r+ t  +++++++l
  EEA21123.1 214 ARKDYITTTQFDGEKERNMMERILTGSTRKCENIL 248
                 55677777888889999999999998888888887 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.0001
         BAR 114 elekrvetnfldplrellekefkeiqkerkklehkrlDyDaakarlkklktkksk 168
                 ++  ++ t++++   + +++e+  +q +++ leh++l +D  k+   k  ++k +
  EEA21123.1 473 PEVNKTHTRLIKQAAHRQAEEMHAVQFMLRYLEHRVLVLDHRKRDGVKTVKEKLS 527
                 5667899999******************************877765555544433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (958 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       420  (0.0234257); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.73u 0.34s 00:00:01.07 Elapsed: 00:00:00.50
# Mc/sec: 5787.12
//
Query:       EEA21124.1  [L=442]
Description: hypothetical protein PMAA_049260 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.1e-15   54.7   4.1    9.1e-15   54.7   4.1    1.5  2  CorA      CorA-like Mg2+ transporter protein


Domain annotation for each model (and alignments):
>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.0      0.32   5.7e+03     147     174 ..      79     106 ..      76     112 .. 0.75
   2 !   54.7   4.1   5.1e-19   9.1e-15     101     290 ..     188     397 ..     173     399 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 0.32
        CorA 147 keilrelaqlrrrlvklrralapnrevl 174
                  e+l+++++ +   v+  + l++++ v+
  EEA21124.1  79 PEMLQSIIDAHNISVQNAETLWDLTSVF 106
                 5778888888888888888888877776 PP

  == domain 2  score: 54.7 bits;  conditional E-value: 5.1e-19
        CorA 101 eggkpkspgellyrlldeivdrlfellekleeeldeledel.......edstkkeilrelaqlrrrlvklrralapnrevlkrlla.kaddkllddedk 191
                 ++++ ks+++l   l+ + v   ++++  le++   + ++        e +  +++l++l+ ++++  ++ ++l +  +vl++l +    +  +++e  
  EEA21124.1 188 QSDDSKSSFWLHQTLFTTYVPAWRHYIASLERRFLPIANTAsasyineELRVGHGHLSTLISIQKDFLQIPTILDAAGDVLTELNTaV--ALDVNQET- 283
                 4678899999999999999999999**********9999999999998889999***************************8666642..33333222. PP

        CorA 192 eylrdlldelerllemlealrerleslqdtyssllser..............lNrvmkvLTvltaiflPlTlitGiyGmNfkglP.elewsygypfvll 275
                 + l+++  + e  ++++++lr+r++   ++++ +l  r              lNr   +LT lt + lP++++t+++GmNf  +  + ++  g+p++++
  EEA21124.1 284 QKLKNIKRQCETYSRTATHLRQRVQMTAQLLADTLLFRdqvlaneqngnmlqLNRSAVFLTTLTLLYLPASFLTSFFGMNFFAMNqQDDTIIGTPMIWI 382
                 447777777777777777777777777777777777777777777667788899999999*************************5666666******* PP

        CorA 276 lglmallailllfwf 290
                 ++++a+l ++ +f +
  EEA21124.1 383 FVVSAILLTVATFIM 397
                 *99999998888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (442 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1036  (0.0577835); expected 358.6 (0.02)
Passed bias filter:                      562  (0.0313459); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.27s 00:00:00.88 Elapsed: 00:00:00.49
# Mc/sec: 2703.52
//
Query:       EEA21125.1  [L=277]
Description: hypothetical protein PMAA_049270 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.19   10.6   1.4       0.25   10.2   1.4    1.1  1  SCAI      Protein SCAI


Domain annotation for each model (and alignments):
>> SCAI  Protein SCAI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   1.4   1.4e-05      0.25     253     311 ..     182     243 ..     165     252 .. 0.58

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 1.4e-05
        SCAI 253 eeaseaaekkeksgsfyqkk...eakseenge.nlaedlsdetkreNphKylLYrPtvsqlla 311
                 ++++++++k ++ g ++++k   +++++++++   +++++++   +N  K  LYrP+++ ll 
  EEA21125.1 182 NHQNPSSSKEKR-GRTTKNKmlfRTSTNTTTKcADQNQQASKPVAQNTTKNYLYRPALQALLE 243
                 223333333333.444444433322222222224445556667789***********999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (277 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       708  (0.0394891); expected 358.6 (0.02)
Passed bias filter:                      419  (0.02337); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.29s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 1806.50
//
Query:       EEA21126.1  [L=672]
Description: amino acid transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      3e-38  131.6  43.3    9.4e-24   83.8  25.7    2.8  2  AA_permease    Amino acid permease
    9.9e-20   70.8  41.3    5.6e-19   68.3  41.3    2.1  2  AA_permease_2  Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.8  25.7     1e-27   9.4e-24       1     230 [.     121     334 ..     121     335 .. 0.93
   2 !   51.7   9.6   5.9e-18   5.3e-14     239     469 ..     362     641 ..     353     649 .. 0.80

  Alignments for each domain:
  == domain 1  score: 83.8 bits;  conditional E-value: 1e-27
  AA_permease   1 hvlvialggviGtglfvglgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgpelGfviGlnylfswitvlaleltaas 98 
                  h+++ ++ g  Gtgl+ + g +l  +Gpl++ll++ll+g+  ++vm+++ e+ ++ p  g+ ++y+s+f++ elG v+G  y+f++ + + + +++++
   EEA21126.1 121 HLFMLTINGTLGTGLYWRGGQILELGGPLAVLLSFLLVGLLAWAVMQCITEMLCIWPIPGALSVYVSEFVDMELGIVVGVTYWFTYSVSFSALVATSA 218
                  899***********************************************************************************999999999999 PP

  AA_permease  99 iliqfwelvtdlpkawvt..gavflvvlliinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkgagfrflgdngsifknnlppgfakee 194
                    + fw  v d  +  +      + v+l+++n +++  y+ +e+ + +iki  ++  ++++iil + +                +f++n  p+     
   EEA21126.1 219 AELVFWPVVNDSKSFQGLviYFAIPVLLILVNAFSIGIYRHVELYTGIIKICFLVVIFVFLIILKFMDWSLVL-----------VFDHNAAPN----- 300
                  99999988888886665533444558999*********************************99999886666...........789999999..... PP

  AA_permease 195 egafknfisvfvivvfaftGielvaiiagEvkdPek 230
                    + ++fi+ ++i+ fa+ G e+va+ a Ev+ P++
   EEA21126.1 301 --WATAFIMSISIATFAYVGVEIVAASALEVQWPRR 334
                  ..99****************************9997 PP

  == domain 2  score: 51.7 bits;  conditional E-value: 5.9e-18
  AA_permease 239 vviritifYvlsllligllvprndlgllndsasa........................aspfvifikesgvsvlaplinaviltaalssansslysas 312
                  + ++ t++Y+l ++l++l +p++d +l   s ++                        +s fv + + s +++l++++n+++  ++ls+a+  ly+as
   EEA21126.1 362 ISVMATLAYTLTSVLATLEIPWDDCQLPRLSWVTttqctspstdmsapsaetgiaeqtSSVFVAIASRSQIPHLGDIFNLFLVFTCLSCASTNLYVAS 459
                  5678999*********************9888889*************************************************************** PP

  AA_permease 313 Rvlyslakd....glaP......kvlkkvskrgvPlraillsmiisl.lalllaslnlaapi....vfnfllaisaliglivwlliilsylrf..... 390
                  R+l+ l  +    +  P      ++++k + ++vP ra+++s+++   + +l   + ++ ++      ++l  +  + +livw + +l+++r+     
   EEA21126.1 460 RALFGLTSRlddgRDQPwylramAYFGKTDSHNVPRRAMIFSAFAFWwVPFLQLRAGTGTDNpigmFVEILAEMGSVGILIVWACNCLAFIRYyhcis 557
                  *****9865222255569999999*****************976543144455555555444112234556666779999999999999996533333 PP

  AA_permease 391 ..Rkalkyqgrsi.........eelgfkaallplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfliilvgvklh 469
                    R al+ +g+s+          + +++  ++p++++ +la ++++l++++ +a+         + +  f+++yliv++f+++lvg kl+
   EEA21126.1 558 thREALEREGISLvrrwstkhpTDYPYRGSGQPFLAYAALAGCMFVLVVANSAALWG------GFYVMPFLSSYLIVMVFIVLLVGMKLK 641
                  33666665554332222222226899*************************999977......456778*****************9986 PP

>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.3  41.3   6.3e-23   5.6e-19       5     403 ..     121     608 ..     117     635 .. 0.76
   2 ?   -0.4   1.9     0.045     4e+02      89     163 ..     595     637 ..     582     652 .. 0.41

  Alignments for each domain:
  == domain 1  score: 68.3 bits;  conditional E-value: 6.3e-23
  AA_permease_2   5 safalvigsvigsgifvkn..laasggpalilwvwiavligslavllvyaEl.ssalprsgGiyvytkaafgkkvaflsawfnwfayvpvlasils 97 
                     +f+l+i+ ++g+g +  +   ++ ggp+++l  ++ v+++ +av+ ++ E+ +  +p  g ++vy++++    ++ +++ ++wf y++++++ ++
     EEA21126.1 121 HLFMLTINGTLGTGLYWRGgqILELGGPLAVLLSFLLVGLLAWAVMQCITEMlCI-WPIPGALSVYVSEFVDMELGIVVGVTYWFTYSVSFSALVA 215
                    68***************9997777799998888888888888**********555.*********************************9966666 PP

  AA_permease_2  98 vaasyllnalgpdlqgntw.ltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfsslstetdtffpngwpgvll 192
                      a+ l++ + p +++++  + ++i++ai +l++l+n+++i +++ +  ++gi+ki  +l++++++ +i+   +++  l+  +++  pn  + +++
     EEA21126.1 216 TSAAELVF-W-PVVNDSKSfQGLVIYFAIPVLLILVNAFSIGIYRHVELYTGIIKI-CFLVVIFVFLIILKFMDWSLVLV-FDHNAAPNWATAFIM 307
                    66666666.5.76777555277**********************************.58888887888888899**9774.456999999999*** PP

  AA_permease_2 193 gllivlwsfdGfesaanvseevk..................k...kdvpkaifigllivlvlyllvniaflgvvpddei.............anls 254
                    +++i++++++G+e +a  + ev+                  +    +v++ ++++ +++++ y+l++++++  +p+d               +   
     EEA21126.1 308 SISIATFAYVGVEIVAASALEVQwprrvktdlsssshrsndTligNTVKFSAIWISVMATLAYTLTSVLATLEIPWDDCqlprlswvtttqcT--- 400
                    *********************8866666666666666664313323566666**************************966666666655441... PP

  AA_permease_2 255 nlgsv..................aalffeavggk...vvaiivvilialsllgaintavigssrvlealard.......gvlP...rffakvnkfg 319
                                            ++f++ +  +    +  i+++++++ +l ++ t ++ +sr l+ l           ++     +f k++ ++
     EEA21126.1 401 ----SpstdmsapsaetgiaeqtSSVFVAIASRSqipHLGDIFNLFLVFTCLSCASTNLYVASRALFGLTSRlddgrdqPWYLramAYFGKTDSHN 492
                    ....044455666667677777544555544432345******************************9877667776665555799********** PP

  AA_permease_2 320 spiraiiltaivslillllfl...........lassaaynfllsvsslgliisyllliigalilrkk....rphlkr.................pg 383
                     p ra+i++a     + + fl           +  +  + +l++++s+g++i+++ + ++ + ++ +    r+ l+r                 p+
     EEA21126.1 493 VPRRAMIFSAFAF--WWVPFLqlragtgtdnpI--GMFVEILAEMGSVGILIVWACNCLAFIRYYHCisthREALERegislvrrwstkhptdyPY 584
                    *********9985..445566568776555542..45677******************99998887632222222446666666555444444433 PP

  AA_permease_2 384 k....ilvaiigalfllfllvalf 403
                    +    + +a  ++ ++ f+lv+++
     EEA21126.1 585 RgsgqPFLAYAALAGCMFVLVVAN 608
                    266655555555555555555443 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.045
  AA_permease_2  89 vpvlasilsvaasyllnalgpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilg 163
                    ++ +  ++++++++ + ++g+++                               +  +l  + i ++++i++++g
     EEA21126.1 595 AALAGCMFVLVVANSAALWGGFY-------------------------------VMPFLSSYLI-VMVFIVLLVG 637
                    22222333333333333333333...............................2222222222.1222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (672 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1115  (0.0621897); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.42
# Mc/sec: 4841.09
//
Query:       EEA21127.1  [L=374]
Description: PAP2 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      4e-27   94.7   0.3    1.3e-26   92.9   0.3    1.9  1  PAP2         PAP2 superfamily
     0.0035   17.7   0.6        2.1    8.8   0.1    2.7  2  DUF805       Protein of unknown function (DUF805)
  ------ inclusion threshold ------
      0.012   15.2   0.4      0.012   15.2   0.4    1.8  3  Sulf_transp  Sulphur transport


Domain annotation for each model (and alignments):
>> PAP2  PAP2 superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.9   0.3   2.2e-30   1.3e-26       2     132 ..     117     319 ..     116     323 .. 0.96

  Alignments for each domain:
  == domain 1  score: 92.9 bits;  conditional E-value: 2.2e-30
        PAP2   2 llalllalalaalltsvlKdlvgrpRPfflaeetkldtqvstletses........................keakesfPSgHsafafalalllalllr 76 
                 ++ l+lala++   t+ lKdl+g+pRP+ +a+++++ ++  t+                             k+++  +PSgHs+f+fa++l+l+l+l+
  EEA21127.1 117 WMGLALALAATFTATEGLKDLIGKPRPDLIARCDPDLSKIATYAVGGLgellqgaptfvtyeicrnqgnnlkKDGFAAWPSGHSSFSFAGMLYLTLWLC 215
                 789999*********************************998877777*********************8888888888******************** PP

        PAP2  77 rkrkkig................................................lvllalillllavlvalsRlylgvHflsDvlaGlliGialaala 127
                  k++                                                   l +la++++++a++va+sR+ +++H  +D++ G ++Gi++a++ 
  EEA21127.1 216 AKFSIAFpyigplpfgartpaatsriqkteaeqasvsttpvsssprhqgaappvyLQILAFVPVCVAFFVACSRYHDHRHAGFDIISGSVVGIFFAYIG 314
                 *****779*****************************************************************************************99 PP

        PAP2 128 yrlvq 132
                 +++++
  EEA21127.1 315 FHMYH 319
                 99886 PP

>> DUF805  Protein of unknown function (DUF805)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.8   0.1   0.00035       2.1      64      95 ..      62      93 ..      53      98 .. 0.87
   2 !    6.7   0.1    0.0015       9.1      44      82 ..     271     309 ..     200     340 .. 0.74

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00035
      DUF805 64 HDtgrsgwllllllvplialllllvllllpgt 95
                HDt  sg+l++++lv   a++l++ ll+ p++
  EEA21127.1 62 HDTVSSGLLIVIGLVIPAAIILVFSLLFVPSN 93
                **************976788888889988876 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0015
      DUF805  44 svvlallllvpslavtvRRlHDtgrsgwllllllvplia 82 
                   +la++ + +++ v+  R HD  + g+ ++ + v  i 
  EEA21127.1 271 LQILAFVPVCVAFFVACSRYHDHRHAGFDIISGSVVGIF 309
                 33344444455599999***********87777664332 PP

>> Sulf_transp  Sulphur transport
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   0.4   1.9e-06     0.012     123     199 ..      59     133 ..      17     170 .. 0.69
   2 ?   -3.9   0.4       1.3     8e+03     288     302 ..     197     211 ..     193     220 .. 0.76
   3 ?   -2.1   0.0      0.37   2.2e+03     113     149 ..     247     283 ..     227     313 .. 0.60

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1.9e-06
  Sulf_transp 123 eslyetlglsplllialllliallllvkelrkeklqeaeklektslakklfrkpwslvlgavllgllavlawllsak 199
                   + ++t++ ++l++i+l++ +a++l++  l  +   +  +l+k+ la ++ rk w++++g++ l+l  ++++ +++ 
   EEA21127.1  59 YAAHDTVSSGLLIVIGLVIPAAIILVFSLLFVPSNLR--ALRKAPLALTWRRKVWEWNAGWMGLALALAATFTATEG 133
                  2334566666667777777777777777666664443..3578888899****************999999988765 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 1.3
  Sulf_transp 288 sgiaslslsgwlalv 302
                  sg +s+s+ g+l+l 
   EEA21127.1 197 SGHSSFSFAGMLYLT 211
                  778888888888775 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 0.37
  Sulf_transp 113 eqllestvskeslyetlglsplllialllliallllv 149
                  eq + st+  +s +++ g +p + + +l+++ +++++
   EEA21127.1 247 EQASVSTTPVSSSPRHQGAAPPVYLQILAFVPVCVAF 283
                  4555555556666677776665555555444332222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (374 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       507  (0.0282782); expected 358.6 (0.02)
Passed bias filter:                      317  (0.0176809); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.49
# Mc/sec: 2302.42
//
Query:       EEA21128.1  [L=686]
Description: hypothetical protein PMAA_049300 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.6e-58  196.3   0.4    1.6e-57  195.4   0.4    1.4  1  DDE_Tnp_1_7      Transposase IS4
    8.6e-12   45.6   9.4    1.8e-11   44.6   9.4    1.6  1  Tnp_zf-ribbon_2  DDE_Tnp_1-like zinc-ribbon


Domain annotation for each model (and alignments):
>> DDE_Tnp_1_7  Transposase IS4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  195.4   0.4   1.8e-61   1.6e-57       2     350 .]     164     577 ..     163     577 .. 0.90

  Alignments for each domain:
  == domain 1  score: 195.4 bits;  conditional E-value: 1.8e-61
  DDE_Tnp_1_7   2 pvelFelflpdkilerivkatNayakqk.........kkwleltaeElkaFlGllllmglvrlpsvedyWstkdfyg....npllseiMsreRFeeil 86 
                  p+++F+lf+++++++ +++ tN+ya  k         ++w+ +t  ElkaF+G+++ mg  + p+++dyW+++++ +    n++ls +++  RFe++ 
   EEA21128.1 164 PYQIFSLFFTEDLFKVLADNTNMYAYAKlsknmnphhRNWRSTTPGELKAFVGAQIYMGFTKEPQLKDYWDEEKHNKsvhaNHPLSNYITCFRFEQLK 261
                  9**********************************************************************9995555678***************** PP

  DDE_Tnp_1_7  87 salhladn........................stkkaekdklkkvrelidslnermqkvyrpsqtlvldeslvlfkgrvpfkqylpgkprkvgiklhv 160
                  + +h++++                        s+++ +    +kv  ++d l +  +++y ps+++++de +v  +gr +    +p+kp   g+k++v
   EEA21128.1 262 RFFHISEPsevpggfistyyrpepteeeelqlSEEQLSGIWWHKVHTVFDILRKASKNLYIPSSNISIDEAMVCSHGRSSHTYKMPNKPISQGFKIFV 359
                  ***********************9999888664444488999******************************************************** PP

  DDE_Tnp_1_7 161 lcdsqtgyilalelyegearnlrl..srelgktnalvlrLleplqgkg..rvvvmdnfftslellqeLakkgtyavGtlkknrsglPkeltqklpkge 254
                  l+d   gy + +++  ++++ ++    +el+kt ++v +L+++l + +  + +++dn+fts++l+++L++ ++ a+Gt +  ++++P+ l++ ++ g+
   EEA21128.1 360 LAD--HGYCYYFYPASRTKGVVEVgmAKELTKTGQMVYELVQTLPKDNktYDLYLDNYFTSVNLFKALREIQVGACGTTRP-HKEFPNLLKKLKDLGS 454
                  ***..9**********999877653378****************965555*******************************.77***88876666666 PP

  DDE_Tnp_1_7 255 llaryg......gplmllkwndrkkvkllstyss....qklveskersg................qki..karpklvedYnqalgavdrhdqllqayr 324
                     +++      +++  ++w d++ v+ l+t+++    ++ +e+ +r+                 q +     p  ++dYn ++g+vd ++q ++ y 
   EEA21128.1 455 YIPYHKvcaipvNDVLCVAWQDNNIVLALTTIHTvdqtDDYIERTRRRPqktstngplvhkefgeQAVknMPIPRFIDDYNSHMGGVDIANQHRAVYD 552
                  666666666666**********************876555588777775677888899999998844543479************************* PP

  DDE_Tnp_1_7 325 aslktskkwykrvlifllsiavvNAy 350
                   ++k+ ++w+  +   +l++ +vNAy
   EEA21128.1 553 THIKAFRSWWP-LWNWCLDVGIVNAY 577
                  **********9.*************9 PP

>> Tnp_zf-ribbon_2  DDE_Tnp_1-like zinc-ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.6   9.4     2e-15   1.8e-11       1      31 []     638     679 ..     638     686 .] 0.94

  Alignments for each domain:
  == domain 1  score: 44.6 bits;  conditional E-value: 2e-15
  Tnp_zf-ribbon_2   1 kRCkvClkkkikke.......TriiCqeCdvplCrnh....C 31 
                      kRC++Cl+k++k++       T++iCq+CdvplCr++    C
       EEA21128.1 638 KRCIWCLYKNPKRQtgqspsfTTFICQACDVPLCRPEtgrtC 679
                      8**********************************9877776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (686 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       434  (0.0242066); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.68u 0.31s 00:00:00.99 Elapsed: 00:00:00.51
# Mc/sec: 4010.50
//
Query:       EEA21129.1  [L=592]
Description: purine permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.2e-69  233.5  31.6    1.4e-68  231.4  31.6    1.8  1  Xan_ur_permease  Permease family


Domain annotation for each model (and alignments):
>> Xan_ur_permease  Permease family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  231.4  31.6   7.9e-73   1.4e-68       4     387 ..      73     496 ..      71     498 .. 0.92

  Alignments for each domain:
  == domain 1  score: 231.4 bits;  conditional E-value: 7.9e-73
                      HHHHHHHHHHHHHHHHHHHHTTTS-..........H.HHHHHHHHHHHHHHHH.........HTTT-----EEE-GGGHHHHHGGG-....... CS
  Xan_ur_permease   4 lllglQhllamfaalvvvPllvgdalgl.aeelrqlisatllasGiatllqll.........ifgirlpillgssfafvtalmialGsa..... 82 
                      +llglQh lam+a+++++P++v+ a+g  + ++++l+s++l++sGi + +q++         ++g++l +++g+sf  +t+   al ++     
       EEA21129.1  73 ILLGLQHALAMLAGVITPPIIVSGAAGFdTSTSQYLVSSSLIVSGILSAIQITrlkirgtpyYIGTGLISVAGTSFSTLTIANNALTQMynsgy 166
                      89***********************877555566**********************************************55555555566678 PP

                      ............HHHHHHHHHHHHHHHHHHHHHHHTT-SH.HHHHH--HHHHHHHHHHHHHHHHHHHHHHTTSS-...BTT............. CS
  Xan_ur_permease  83 ..........edieialagllgallvagvlfilisltglrgrlarlipPvvtgpvvlliGlslaqiavkkvgggwaa.veg............. 152
                                     +++++lg+  + ++l i +s++ + + + r++pP+vtgp+v+liG sl++ ++k+ +gg  a + +             
       EEA21129.1 167 cpidpetgakLACPQGYGAILGTSCLCSLLEIGLSFVPI-DVIKRIFPPLVTGPTVMLIGVSLIESGLKNWAGGSGAcLANaasralcpsatap 259
                      9***9999886788999**********************.6****************************9999876654333555556666666 PP

                      ...B---HHHHHHHHHHHHHHHHHHHSSSTTTTTHHHHHHHHHHHHHHHHHHHTTSSHHHHS-SS-----------HH..H.HHHHTHHH.HHH CS
  Xan_ur_permease 153 ..ltvvslkllllavvvllvilllsvflkglfsqlpiLigiiagwllalfmgivnlspevseapwfqlpsplkfgtplfnlgliltvlavalva 244
                        l+ +s ++++l++ v + i+l+ +f ++++++ ++ +g+++g+++a+++g ++ s+ +++ap++++   +k ++ ++ ++lil +la+++v+
       EEA21129.1 260 hpLPWGSAEFIGLGFLVFVSIILCERFGSPIMRTCSVAVGLLVGCIVAAACGYFDPSS-IQQAPVASFV-WVKTFPLSIYAPLILPFLALYIVL 351
                      778899****************************************************.99**999996.5566666699************** PP

                      HHHHHHHHHHHHHHHTS-TII...IIIHHHHHHHHHHHHHHHHHHT---EEE-HHHHHHHHHHTB--HHHHHHHHHHHHHHT--HHHHHHHTTS CS
  Xan_ur_permease 245 vvesvGdiravakvvgrslkp...kpdlrralladGlatllsgllGalpvttyaeniGvvaltkvasrrvmvtagvilillglipklaallssI 335
                      ++e++Gdi+a+ +v+++++++   ++++r ++ladGl+ ll+gl+  +pv+t+a+n+Gv+alt+ a+r+ + +   +li++g+++k+aa l +I
       EEA21129.1 352 MMEAIGDITATCDVSRLDIEGelfDSRIRGGVLADGLNGLLAGLFTITPVSTFAQNNGVIALTRCANRKAGYWCCFFLIVMGIFSKFAAALVAI 445
                      ********************************************************************************************** PP

                      -HHHHHHHHHHHHHHHHHHHHHHHHHTTS-SHHHHHHHHHHHHHHHH----- CS
  Xan_ur_permease 336 PepvlgGvllvvfgmiaasgvsnlqtvdldsarnllivavslvlGlgvatvp 387
                      P+ vlgG+++ +f+++a+sg++++    ++ +rn +i+  + ++G+g++ vp
       EEA21129.1 446 PSSVLGGMTTFLFSSVAISGIRIIAATPFT-RRNRFILTAAFAVGMGATLVP 496
                      ******************************.999999988888888887766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (592 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       637  (0.035529); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.31s 00:00:00.96 Elapsed: 00:00:00.52
# Mc/sec: 3422.94
//
Query:       EEA21130.1  [L=200]
Description: succinate dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      3e-22   78.9   1.2    4.2e-22   78.4   1.2    1.2  1  Sdh_cyt   Succinate dehydrogenase/Fumarate reductase transmem


Domain annotation for each model (and alignments):
>> Sdh_cyt  Succinate dehydrogenase/Fumarate reductase transmembrane subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.4   1.2   2.4e-26   4.2e-22       2     119 ..      70     195 ..      69     197 .. 0.86

  Alignments for each domain:
  == domain 1  score: 78.4 bits;  conditional E-value: 2.4e-26
     Sdh_cyt   2 rknrplsphlqlyrlplgawlsilhritGvallvglllllvwlllalslsspesfarv.........vallaspiklilllllllallyHllnGiRhll 91 
                 r +rp+sph+++y++++ ++ sil+r++G +l++g++++ + +l+a+++s +   ++v         ++ ++++ k+   ++l+l++ yH++nG++hl+
  EEA21130.1  70 RLRRPVSPHITIYKWQYQSLTSILQRFSGMFLAGGIYVFAIGYLVAPTISPGL--EQVfdletivsaAREVPGWAKSGGKFALALPFTYHFFNGVKHLM 166
                 679*******************************8888888889999777555..444445666776666667999*********************** PP

     Sdh_cyt  92 wDlglgl.elesarksalavlalavalvl 119
                 wD g+gl +++   + a++v + +v+++l
  EEA21130.1 167 WDSGIGLaHKRLFGRFAWIVAGCSVVSSL 195
                 *******9999999999999999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (200 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       347  (0.0193541); expected 358.6 (0.02)
Passed bias filter:                      283  (0.0157845); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.28s 00:00:00.71 Elapsed: 00:00:00.44
# Mc/sec: 1368.55
//
Query:       EEA21131.1  [L=199]
Description: succinate dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      3e-22   78.9   1.2    4.2e-22   78.4   1.2    1.2  1  Sdh_cyt   Succinate dehydrogenase/Fumarate reductase transmem


Domain annotation for each model (and alignments):
>> Sdh_cyt  Succinate dehydrogenase/Fumarate reductase transmembrane subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.4   1.2   2.3e-26   4.2e-22       2     119 ..      69     194 ..      68     196 .. 0.86

  Alignments for each domain:
  == domain 1  score: 78.4 bits;  conditional E-value: 2.3e-26
     Sdh_cyt   2 rknrplsphlqlyrlplgawlsilhritGvallvglllllvwlllalslsspesfarv.........vallaspiklilllllllallyHllnGiRhll 91 
                 r +rp+sph+++y++++ ++ sil+r++G +l++g++++ + +l+a+++s +   ++v         ++ ++++ k+   ++l+l++ yH++nG++hl+
  EEA21131.1  69 RLRRPVSPHITIYKWQYQSLTSILQRFSGMFLAGGIYVFAIGYLVAPTISPGL--EQVfdletivsaAREVPGWAKSGGKFALALPFTYHFFNGVKHLM 165
                 679*******************************8888888889999777555..444445666776666667999*********************** PP

     Sdh_cyt  92 wDlglgl.elesarksalavlalavalvl 119
                 wD g+gl +++   + a++v + +v+++l
  EEA21131.1 166 WDSGIGLaHKRLFGRFAWIVAGCSVVSSL 194
                 *******9999999999999999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (199 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       348  (0.0194099); expected 358.6 (0.02)
Passed bias filter:                      285  (0.015896); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1440.45
//
Query:       EEA21132.1  [L=442]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.2e-13   49.5   0.0      4e-10   39.4   0.0    2.4  2  Rad51         Rad51
    4.9e-07   29.5   0.1    8.2e-06   25.5   0.0    2.2  2  RecA          recA bacterial DNA recombination protein
    2.7e-06   26.9   0.1    5.2e-06   26.0   0.1    1.5  1  ATPase        KaiC
    2.2e-05   24.1   0.3    0.00021   20.9   0.0    2.5  3  AAA_25        AAA domain
     0.0024   17.3   0.0      0.014   14.7   0.0    2.0  2  DnaB_C        DnaB-like helicase C terminal domain
  ------ inclusion threshold ------
      0.014   14.5   0.0      0.031   13.5   0.0    1.5  2  NB-ARC        NB-ARC domain
      0.022   14.5   0.0      0.051   13.3   0.0    1.7  1  AAA_24        AAA domain
       0.04   14.3   0.1       0.14   12.5   0.0    1.9  2  RNA_helicase  RNA helicase
      0.045   13.2   0.0      0.082   12.4   0.0    1.3  1  PhoH          PhoH-like protein
      0.051   14.0   0.6       0.15   12.5   0.1    2.0  2  AAA           ATPase family associated with various cellular 
      0.073   13.0   0.0       0.13   12.2   0.0    1.3  1  ATPase_2      ATPase domain predominantly from Archaea
       0.11   12.8   0.0       0.27   11.5   0.0    1.7  2  AAA_22        AAA domain


Domain annotation for each model (and alignments):
>> Rad51  Rad51
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.4   0.0   2.7e-13     4e-10      29     158 ..      62     203 ..      21     212 .. 0.85
   2 !    7.8   0.0    0.0012       1.8     162     194 ..     240     272 ..     227     335 .. 0.77

  Alignments for each domain:
  == domain 1  score: 39.4 bits;  conditional E-value: 2.7e-13
                 HHTSSEESSSEEEEEESTTSSHHHHHHHHHHHTTS-TTTS--SSEEEEEESSS---GGGGHHHH................HHTT--HHHHGGGEEEEE- CS
       Rad51  29 lLgGGietgsiteifGefrsGktqlchtlcvtvqlplelgGgegkavyidtegtfrperlveia................erykldkeevlenvayaRa 111
                 lL+ Gi+ gsitei+G  + Gkt ++ +++  v     + G ++k+++idt + +   rl ++                      + ++++ +v   Ra
  EEA21132.1  62 LLSSGIPRGSITEIYGPPGVGKTAFSLNIAAKVL----TAGDDEKVIWIDTGSPIPKPRLRDLLisniksstttttttteVDITNKLNDCITRVIHIRA 156
                 6899********************9988887653....579**************999*9998778999999999876422223445799********* PP

                 -STTHHHHHHHHTHHHHHHS-EEEEEEETTTGGGCH-------THHH CS
       Rad51 112 ytiehqeellqqaaallaedkfallivDsvtalyRtdfsgrgelakR 158
                 ++  h  +l ++ +  +  +  +l+++D+v a + + f +  el +R
  EEA21132.1 157 HSLPHLLSLFTHPPPNFPPKGTSLIVIDTVSAPFQSYFPNATELKSR 203
                 ****************************************9999987 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0012
                 HHHHHHHHHHHHHHH--EEEEEEE-------.- CS
       Rad51 162 lgkllrtLrkladefevavvitnqvvaqvdgqa 194
                  + ++++++k+a  +++av++ nq   ++ gq 
  EEA21132.1 240 TSDMINKITKFAATHNLAVIVLNQTHTKIKGQP 272
                 4678899*******************9998864 PP

>> RecA  recA bacterial DNA recombination protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.5   0.0   5.5e-09   8.2e-06      32      82 ..      43      99 ..      31     127 .. 0.78
   2 ?    1.4   0.0      0.12   1.8e+02     164     193 ..     239     268 ..     231     275 .. 0.89

  Alignments for each domain:
  == domain 1  score: 25.5 bits;  conditional E-value: 5.5e-09
                -EE--S-HHHHHHTSS......SSEETTSEEEEEESTTSSHHHHHHHHHHHHHHTT- CS
        RecA 32 etissGslaldialGi......GGlpkGriieiyGpessGkttlalhaiaeaqkkgg 82
                 ++++G  +ld al +       G+p+G i+eiyGp   Gkt+++l++ a++  +g 
  EEA21132.1 43 RSLPTGLDGLDDALCVttgllsSGIPRGSITEIYGPPGVGKTAFSLNIAAKVLTAGD 99
                567777777777776533223369**************************9988875 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.12
                 HHHHHHHHHHHHHTTT--EEEEEEE----- CS
        RecA 164 lmsqalrkltgaisksntvvifinqireki 193
                 + s  + k+t   +  n +vi +nq  +ki
  EEA21132.1 239 VTSDMINKITKFAATHNLAVIVLNQTHTKI 268
                 5688999*******************9998 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0   0.1   3.5e-09   5.2e-06       2      56 ..      46     108 ..      45     144 .. 0.85

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 3.5e-09
      ATPase   2 ktgIeglDeilk.......gGipegrvvlitGepGtGKtifalqFlikgaek.ygepgvfvtv 56 
                 +tg  glD+ l         Gip+g+++ i+G pG GKt f+l+ + k +    +e+++ + +
  EEA21132.1  46 PTGLDGLDDALCvttgllsSGIPRGSITEIYGPPGVGKTAFSLNIAAKVLTAgDDEKVIWIDT 108
                 8********9966899999***********************998877644312567777655 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.0   1.4e-07   0.00021      25      60 ..      62      97 ..      39     132 .. 0.82
   2 ?   -0.5   0.0      0.52   7.8e+02     142     153 ..     177     188 ..     175     202 .. 0.80
   3 ?   -2.0   0.1       1.5   2.2e+03     166     187 ..     241     262 ..     234     265 .. 0.80

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 1.4e-07
      AAA_25 25 lvkgllpagelallaGapgtGKttlaldlalavatG 60
                l+   +p+g+++ ++G+pg+GKt++ l++a++v+t 
  EEA21132.1 62 LLSSGIPRGSITEIYGPPGVGKTAFSLNIAAKVLTA 97
                556567***************************953 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.52
      AAA_25 142 gvrlvviDplsr 153
                 g  l+viD++s+
  EEA21132.1 177 GTSLIVIDTVSA 188
                 5789*****997 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 1.5
      AAA_25 166 galvealeriarrtgaavllvh 187
                 + +++++ ++a+ ++ av+++ 
  EEA21132.1 241 SDMINKITKFAATHNLAVIVLN 262
                 5689999999999999999876 PP

>> DnaB_C  DnaB-like helicase C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   9.5e-06     0.014      13      54 ..      64     106 ..      45     159 .. 0.74
   2 ?   -0.3   0.0      0.36   5.3e+02     154     213 ..     240     297 ..     225     322 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 9.5e-06
                 CTSBXTTXEEEEEEXTTSSHHHHHHHHHHHHHHCST.SEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxx RF
      DnaB_C  13 tsGlqkgdliiiAarpsmGktalalniaenaavkek.lpvavf 54 
                  sG+ +g ++ i + p++Gkta+ lnia+++ +  +  +v+ +
  EEA21132.1  64 SSGIPRGSITEIYGPPGVGKTAFSLNIAAKVLTAGDdEKVIWI 106
                 57889999999*****************998754331456554 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.36
                 HHHHHHHHHHHHHHCTSXEEEEEEXSGGGCCSCCHSXXHHHHCCTTSCCCCXSEEEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      DnaB_C 154 vseisrsLkalakelnvpvialsqLsravesredkrPvlsDLreSgsieqdADvvlflyr 213
                  s++  ++ ++a   n+ vi+l q   +++ +   rP+l      gs e    + ++lyr
  EEA21132.1 240 TSDMINKITKFAATHNLAVIVLNQTHTKIKGQ--PRPTLYPALAGGSWETCVQTRIVLYR 297
                 46777888899999999999999988777644..67776555555555555555555555 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   2.1e-05     0.031      20      97 ..      70     145 ..      57     156 .. 0.76
   2 ?   -4.0   0.0       4.6   6.8e+03     133     156 ..     384     406 ..     377     412 .. 0.61

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.1e-05
                 SEEEEEEESTTSSHHHHHHHHCCSHCCCCCCBTEEEEEEEESXXHHHHHHHXXHHHHHCCCTTSSSS-STTSHHHHHH CS
      NB-ARC  20 slvvalvGmgGvGKttlakqilnksdevegrFdsvawvvvsktdkseeiletilkeLslseddleekeeveslkrklv 97 
                   +  ++G +GvGKt  + +i  k   + g  + v+w+  +    + ++ + ++ +++ s   +   +ev+ + +kl 
  EEA21132.1  70 GSITEIYGPPGVGKTAFSLNIAAK-VLTAGDDEKVIWIDTGSPIPKPRLRDLLISNIKSSTTTTTTTTEVD-ITNKLN 145
                 56788*******************.88888999*****888888888887777777777766666666665.555544 PP

  == domain 2  score: -4.0 bits;  conditional E-value: 4.6
                 EEEEEESBCCCCCCS-S-EEEEEE CS
      NB-ARC 133 rvllTTRdeevanavsatsekiev 156
                   ++T R+++v +++   ++  e 
  EEA21132.1 384 TSAMTVRKRKVDEIADS-EDEDED 406
                 55788888888554444.444444 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   3.4e-05     0.051       7      76 ..      75     188 ..      72     244 .. 0.63

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 3.4e-05
      AAA_24   7 iyGpsgiGKTtlakelgpkplfidtekGlksldadkfpdie.............................swedfldevvel................. 59 
                 iyGp+g+GKT + +++  k+l    ++  k +  d +  i+                             +++d++  v  +                 
  EEA21132.1  75 IYGPPGVGKTAFSLNIAAKVLTAGDDE--KVIWIDTGSPIPkprlrdllisnikssttttttttevditnKLNDCITRVIHIrahslphllslfthppp 171
                 9***************55554443333..2333333222222223333333333433333333222222333333333333377777777777777777 PP

      AAA_24  60 aaeladyktlviDtide 76 
                 +  +++ + +viDt++ 
  EEA21132.1 172 NFPPKGTSLIVIDTVSA 188
                 66677777777777765 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   9.5e-05      0.14       3      34 ..      75     106 ..      74     114 .. 0.83
   2 ?   -3.2   0.1       7.6   1.1e+04      28      57 ..     402     431 ..     386     440 .. 0.62

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 9.5e-05
  RNA_helicase   3 lyGpsgeGKStlakeLakallkklklkkkdsv 34 
                   +yGp+g+GK+ ++ ++a+++l++ +++k  ++
    EEA21132.1  75 IYGPPGVGKTAFSLNIAAKVLTAGDDEKVIWI 106
                   7********************88876665555 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 7.6
  RNA_helicase  28 lkkkdsvysrnpeddfwdgYtgqevvvidD 57 
                   ++ +d++  ++ +d  wdg +++e v  d+
    EEA21132.1 402 DEDEDEFLEGQDDDFRWDGDQDEESVPLDE 431
                   444455555555555577777777666665 PP

>> PhoH  PhoH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   5.5e-05     0.082      19      54 ..      70     105 ..      62     108 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 5.5e-05
                 -SEEEEE--TTSSTTHHHHHHHHHHHHTTS-SEEEE CS
        PhoH  19 ndivfaiGpaGtGKtylavalavealkkkkvkriil 54 
                  +i+ + Gp G GKt +++ +a+++l++++ +++i 
  EEA21132.1  70 GSITEIYGPPGVGKTAFSLNIAAKVLTAGDDEKVIW 105
                 578999************************999996 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.1    0.0001      0.15       3      22 ..      75      94 ..      74     129 .. 0.86
   2 ?   -3.3   0.0       7.6   1.1e+04      41      64 ..     239     261 ..     232     270 .. 0.56

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.0001
                EESSTTSSHHHHHHHHHHHH CS
         AAA  3 lyGppGtGKTllakavakel 22
                +yGppG+GKT++   +a ++
  EEA21132.1 75 IYGPPGVGKTAFSLNIAAKV 94
                69*********999999874 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 7.6
                 HHHHHHHHHHHHHHHTSTSEEEEE CS
         AAA  41 esekkirelfkeakekakpsilfi 64 
                  +++ i+++ k a +++   ++++
  EEA21132.1 239 VTSDMINKITKFAATHN-LAVIVL 261
                 45555555555555554.445444 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   8.5e-05      0.13      21      68 ..      71     120 ..      67     158 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 8.5e-05
    ATPase_2  21 eiyfiYGpegsGKtaLlkeiienledkdk..yviyyialreesiskldef 68 
                 +i  iYGp g+GKta+  +i+ + +  ++  +vi+++  + +   +l++ 
  EEA21132.1  71 SITEIYGPPGVGKTAFSLNIAAKVLTAGDdeKVIWIDTGSPIPKPRLRDL 120
                 5777************9999998865544448888887766666666555 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   0.00018      0.27       6      70 ..      71     131 ..      68     211 .. 0.66
   2 ?   -3.2   0.0       6.2   9.2e+03      74     127 ..     239     260 ..     223     265 .. 0.52

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00018
      AAA_22   6 gilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelka 70 
                 +i+ ++G++G+GKT    +++ +   +      + +v+ ++  s+     l+  l +++++++ +
  EEA21132.1  71 SITEIYGPPGVGKTAFSLNIAAKVLTA----GDDEKVIWIDTGSPIPKPRLRDLLISNIKSSTTT 131
                 7888***********999999987433....3455555555555554444444444444444444 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 6.2
      AAA_22  74 sseellealeqalraravielliiDEaqhlrseealeeLrsllnlsrkgvqliL 127
                  +                               ++++++ +++   ++++++i+
  EEA21132.1 239 VT------------------------------SDMINKITKFAA--THNLAVIV 260
                 33..............................444444444444..55555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (442 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       804  (0.0448435); expected 358.6 (0.02)
Passed bias filter:                      467  (0.0260472); expected 358.6 (0.02)
Passed Vit filter:                        70  (0.00390429); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.61u 0.30s 00:00:00.90 Elapsed: 00:00:00.48
# Mc/sec: 2790.60
//
Query:       EEA21133.1  [L=247]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.5e-08   32.8   0.6    1.9e-07   31.3   0.1    1.9  2  SAP30_Sin3_bdg  Sin3 binding region of histone deacetylase co
  ------ inclusion threshold ------
        2.1    9.3   5.1       0.29   12.1   0.9    1.6  2  Alb1            Alb1


Domain annotation for each model (and alignments):
>> SAP30_Sin3_bdg  Sin3 binding region of histone deacetylase complex subunit SAP30
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.1      0.28   2.5e+03       4      17 ..     113     126 ..     111     130 .. 0.77
   2 !   31.3   0.1   2.2e-11   1.9e-07      15      54 .]     195     233 ..     190     233 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.28
  SAP30_Sin3_bdg   4 ntLrrYkrhyklek 17 
                     + L  Y+  ykl++
      EEA21133.1 113 SILHDYRHAYKLST 126
                     67888*******54 PP

  == domain 2  score: 31.3 bits;  conditional E-value: 2.2e-11
  SAP30_Sin3_bdg  15 lekvrpgsskeqLaeaVarHFkaqpvdEkevitsFlyavk 54 
                     + + ++   keqLa aV++HF+a  + E+++i+ Fly+v+
      EEA21133.1 195 I-NSQDRVGKEQLALAVRKHFNAAGLVEQDAIARFLYKVR 233
                     5.5567778*****************************97 PP

>> Alb1  Alb1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.2         1   9.2e+03      30      32 ..      66      68 ..      41      88 .. 0.48
   2 ?   12.1   0.9   3.2e-05      0.29       5      61 ..     152     212 ..     151     229 .. 0.75

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 1
        Alb1 30 dre 32
                +++
  EEA21133.1 66 KVA 68
                222 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 3.2e-05
        Alb1   5 Aarraespslnldkslkslprpektdrertavlnea.lsagisk..kkkk..kkklskklrl 61 
                 Aarra+  +  + + ++s ++p +t r+r+a+l+++ + + ++k  ++ +  k++l+ ++r+
  EEA21133.1 152 AARRAAAVATTATT-SSSSTSPGPTHRSRPAALKPTtETNRVNKinSQDRvgKEQLALAVRK 212
                 89**9987665555.55556669*************99999***753333455566655554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (247 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       769  (0.0428914); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.32s 00:00:00.82 Elapsed: 00:00:00.47
# Mc/sec: 1564.01
//
Query:       EEA21134.1  [L=415]
Description: C2H2 transcription factor (Crea), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.1e-07   32.0  20.4    5.8e-05   23.3   3.3    4.3  4  zf-H2C2_2    Zinc-finger double domain
    1.9e-05   24.8  14.0    0.00078   19.8   4.5    3.4  4  zf-C2H2      Zinc finger, C2H2 type
  ------ inclusion threshold ------
      0.037   14.9  20.3      0.054   14.3   3.0    3.4  3  zf-C2H2_4    C2H2-type zinc finger
      0.048   14.0   0.2       0.12   12.6   0.2    1.7  1  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
      0.055   14.1   1.4       0.16   12.6   0.2    2.3  2  FOXP-CC      FOXP coiled-coil domain
       0.14   12.2   0.8        9.2    6.4   0.2    2.5  2  zf-C2H2_6    C2H2-type zinc finger


Domain annotation for each model (and alignments):
>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   0.7   1.9e-05     0.058      12      24 ..      72      84 ..      72      86 .. 0.89
   2 !   23.3   3.3     2e-08   5.8e-05       3      25 ..      91     115 ..      91     116 .. 0.89
   3 ?    4.9   0.2     0.013        38       2      13 ..     120     131 ..     119     133 .. 0.89
   4 ?   -0.6   0.1      0.74   2.2e+03       4      10 ..     334     340 ..     333     346 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.9e-05
   zf-H2C2_2 12 ekpyeCplCdkaF 24
                ++py+CplCd aF
  EEA21134.1 72 PRPYKCPLCDRAF 84
                68**********9 PP

  == domain 2  score: 23.3 bits;  conditional E-value: 2e-08
   zf-H2C2_2   3 rrHirkHtgekpyeCp..lCdkaFk 25 
                 +rHir+Htgekp+ C    C k+F+
  EEA21134.1  91 TRHIRTHTGEKPHACQfpGCTKRFS 115
                 59**************666****97 PP

  == domain 3  score: 4.9 bits;  conditional E-value: 0.013
   zf-H2C2_2   2 LrrHirkHtgek 13 
                 L+rH r H +++
  EEA21134.1 120 LTRHSRIHNNPN 131
                 99******9986 PP

  == domain 4  score: -0.6 bits;  conditional E-value: 0.74
   zf-H2C2_2   4 rHirkHt 10 
                 rH+  H+
  EEA21134.1 334 RHLSLHH 340
                 9***876 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   4.5   2.6e-07   0.00078       1      23 []      75      97 ..      75      97 .. 0.99
   2 !   18.4   2.0   7.1e-07    0.0021       2      23 .]     104     127 ..     103     127 .. 0.92
   3 ?   -2.0   0.0       2.2   6.6e+03      14      21 ..     189     196 ..     187     197 .. 0.80
   4 ?   -5.0   2.2         6   1.8e+04      18      23 .]     334     339 ..     333     340 .. 0.76

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 2.6e-07
                EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCpdCgksFkrksnLkrHirtH 23
                ykCp C++ F r ++ +rHirtH
  EEA21134.1 75 YKCPLCDRAFHRLEHQTRHIRTH 97
                9*********************9 PP

  == domain 2  score: 18.4 bits;  conditional E-value: 7.1e-07
                 EET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2   2 kCp..dCgksFkrksnLkrHirtH 23 
                  C   +C+k+F+r+++L+rH r+H
  EEA21134.1 104 ACQfpGCTKRFSRSDELTRHSRIH 127
                 58888*****************99 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 2.2
                 HHHHHHHH CS
     zf-C2H2  14 snLkrHir 21 
                  n+++H+r
  EEA21134.1 189 TNYTSHLR 196
                 58999998 PP

  == domain 4  score: -5.0 bits;  conditional E-value: 6
                 HHHHCC CS
     zf-C2H2  18 rHirtH 23 
                 rH++ H
  EEA21134.1 334 RHLSLH 339
                 899995 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   3.0   1.8e-05     0.054       1      23 [.      75      97 ..      75      98 .. 0.96
   2 ?   12.5   1.2   7.2e-05      0.21       2      23 ..     104     127 ..     103     128 .. 0.89
   3 ?   -2.7   1.7       5.5   1.6e+04      18      24 .]     334     340 ..     333     340 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 1.8e-05
   zf-C2H2_4  1 fkCpiCgksFsskkaLlrHlkth 23
                +kCp+C++ F++ ++  rH++th
  EEA21134.1 75 YKCPLCDRAFHRLEHQTRHIRTH 97
                8**************999****9 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 7.2e-05
   zf-C2H2_4   2 kCpi..CgksFsskkaLlrHlkth 23 
                  C +  C+k+Fs++++L rH + h
  EEA21134.1 104 ACQFpgCTKRFSRSDELTRHSRIH 127
                 688888**************9998 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 5.5
   zf-C2H2_4  18 rHlkthH 24 
                 rHl  hH
  EEA21134.1 334 RHLSLHH 340
                 8*****9 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.2   4.1e-05      0.12       2      24 ..      75      97 ..      74     103 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 4.1e-05
                 CBBTTTTBBBSSHHHHHCCTTSH CS
  zf-C2H2_jaz  2 fYCvlCdKyFksenaldnHlkSK 24
                 + C+lCd+ F+  +    H++++
   EEA21134.1 75 YKCPLCDRAFHRLEHQTRHIRTH 97
                 89******************994 PP

>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.1       0.8   2.4e+03      10      28 ..      78      96 ..      76     103 .. 0.83
   2 ?   12.6   0.2   5.5e-05      0.16       6      36 ..     104     134 ..     101     143 .. 0.84

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.8
     FOXP-CC 10 PgCekvledveeflkhlns 28
                P C+++++ +e+ ++h+++
  EEA21134.1 78 PLCDRAFHRLEHQTRHIRT 96
                8899999999999999976 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 5.5e-05
     FOXP-CC   6 vCkWPgCekvledveeflkhlnseHalddks 36 
                  C+ PgC k ++ ++e+++h + + +++++ 
  EEA21134.1 104 ACQFPGCTKRFSRSDELTRHSRIHNNPNSRR 134
                 7*******************98888877765 PP

>> zf-C2H2_6  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.2    0.0031       9.2       2      14 ..      75      87 ..      75      89 .. 0.92
   2 ?    3.5   0.0     0.025        75       7      24 ..     110     127 ..     108     128 .. 0.91

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0031
   zf-C2H2_6  2 heCsvCsksFpsl 14
                ++C+ C++ F+ l
  EEA21134.1 75 YKCPLCDRAFHRL 87
                9*********976 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.025
   zf-C2H2_6   7 CsksFpslqaLggHkksH 24 
                 C k+F+  ++L+ H + H
  EEA21134.1 110 CTKRFSRSDELTRHSRIH 127
                 99************9866 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (415 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       696  (0.0388198); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.64u 0.33s 00:00:00.97 Elapsed: 00:00:00.54
# Mc/sec: 2316.61
//
Query:       EEA21135.1  [L=1016]
Description: signal transduction protein BroA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.2e-135  452.3   4.9   3.8e-135  450.6   4.9    1.9  1  BRO1            BRO1-like domain
    1.3e-81  274.2  15.7    1.3e-81  274.2  15.7    2.0  2  ALIX_LYPXL_bnd  ALIX V-shaped domain binding to HIV
  ------ inclusion threshold ------
       0.33   11.0   1.0         18    5.5   0.1    2.6  2  DUF3012         Protein of unknown function (DUF3012)
       0.57   10.3   3.5        2.5    8.2   0.6    2.7  2  DUF2120         Uncharacterized protein conserved in archaea 
          3    8.0  10.7        2.6    8.2   4.5    3.4  3  DUF148          Domain of unknown function DUF148
          5    7.1   5.6         92    2.9   5.6    2.7  1  PXA             PXA domain


Domain annotation for each model (and alignments):
>> BRO1  BRO1-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  450.6   4.9  1.3e-138  3.8e-135       1     389 []       6     393 ..       6     393 .. 0.97

  Alignments for each domain:
  == domain 1  score: 450.6 bits;  conditional E-value: 1.3e-138
                 XXXXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.....XXXX.XXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXX CS
        BRO1   1 llsiplKkteekevdlkkpLknyIsetygsqdpeafeddlaelnklRqdavrksankdsesglelllkYyaqLellelrfpieeqslkveFtWydafss 99 
                 +ls+plK+t+e  +d+++pLk+yI++ yg +dp+++++++a+ln+lRqd +r+ a+kds+sg++ll++Yy+qLell+lrfp++e+++k++FtWydaf+ 
  EEA21135.1   6 MLSCPLKQTSE--IDWVQPLKDYIRTAYG-DDPDRYQEECATLNRLRQD-MRG-AGKDSASGRDLLYRYYGQLELLDLRFPVDENHIKISFTWYDAFT- 98 
                 99*******55..***************8.99*****************.556.89999***********************98899**********5. PP

                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..XXX.XXXXXXXXXXXXXXXXXXXXXXXXXXX....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        BRO1 100 skkvtqsslafEkasvLFniaalysqlaasqnrstdeglkrackyfqqAAgvfqylkenflhapteeesedlspetlkaLeklmlAqAqecflekaikd 198
                 +k+++q+slafEkas+LFni a++s+ aa+qnr++d glk+a+++fq++Ag+f+y++enflhap    s+dls++t+kaL ++mlAqAqe+flek + d
  EEA21135.1  99 QKPTSQYSLAFEKASILFNISAVLSCHAANQNRADDTGLKTAFHSFQASAGMFTYINENFLHAP----STDLSRSTVKALINVMLAQAQEIFLEKQTAD 193
                 99**************************************************************....****************************99* PP

                 XXXXXXXXXXXXXXXXXXXXXXXXXX.......XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....... CS
        BRO1 199 nkkdsliaKlaaqvaelYeealealkkselidekeevlkklldksWikhvqvKashfkAlaqyrqalaaeeakkyGeeiarlqkAlellkea....... 290
                 +kk++++aKla+q+a lY++a+e++        +e v+k+ ++k W+ ++q+Kash++++a ++qa a+ e++ +G +iarlq A +l   a       
  EEA21135.1 194 GKKAGVLAKLASQAAWLYTQAAETV--------QEYVGKGFFEKVWSLVIQAKASHMASVASFHQAKADSESNSHGVAIARLQLAAKLSAAAvtwaksf 284
                 *************************........8899***************************************************9999******* PP

                 .........X...........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXHHHHHHH CS
        BRO1 291 .........lkskkaeelledlkglkdvveeklkeaekDNdlIYheevPsesslpeikkaslvkaipleeeke.eekseesgkdlFakLvPlsvheaas 379
                          l s++  +l e++k+++ +vee+ +++ +DNd+IYh++vP+e+ l++i k++++kaip++e ++ +++++++g+d+F+kLvP+sv+e+as
  EEA21135.1 285 pssvpansnLVSEDGASLMEEIKRHQAIVEEQVSTLIRDNDFIYHQPVPNEAGLSAIAKLAVAKAIPVSELYQgQDIQRIIGPDIFQKLVPMSVTESAS 383
                 *99999998555566778**************************************************998888************************* PP

                 HHHHHHHHHH CS
        BRO1 380 ayserkaklv 389
                 +y+e+kakl+
  EEA21135.1 384 LYDEEKAKLI 393
                 ********97 PP

>> ALIX_LYPXL_bnd  ALIX V-shaped domain binding to HIV
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  274.2  15.7   4.2e-85   1.3e-81       2     295 .]     433     759 ..     432     759 .. 0.92
   2 ?   -1.1   0.6      0.32   9.4e+02     124     150 ..     768     794 ..     761     796 .. 0.68

  Alignments for each domain:
  == domain 1  score: 274.2 bits;  conditional E-value: 4.2e-85
  ALIX_LYPXL_bnd   2 lPpsllekaeevrsqgglqrlekllqdlqelkerneeiLdeieklLdeEesedeklrakygtrWtrqpSseltaelraelqkyreileeAsesDk 96 
                     +++++++++ee++   ++  ++k l++lq++k+ + ++L +++++Ld+Ees++ek+r+kyg++Wt+qpSs+lta+lr e++++r +++eA++sD+
      EEA21135.1 433 VDEEFRRWCEEMA---DHTGFHKTLDELQDSKAIIVDSLSQCTRQLDMEESVCEKMRSKYGADWTQQPSSRLTATLRGEIRSLRDTINEAGASDT 524
                     899**********...9****************************************************************************** PP

  ALIX_LYPXL_bnd  97 ivrqklqenkedlelLsgpeeeleaalp.........ssssa........................aa..sesveeqirklrsllekldelkaer 156
                     ++ ++l+++++d++++ +  e +ea +              +                        ++  s+sv eqi ++++ll+kl+ +k+er
      EEA21135.1 525 QLNATLKQYEADFDEMRSAGETDEADVLyqramvkagA---KqkvsrngqaspyspgnegsllddvEDegSLSVAEQITRVEELLKKLNLVKRER 616
                     ****************7766677777553444444440...15566677888888888888876551167************************* PP

  ALIX_LYPXL_bnd 157 eqllkdlkekaendDitpklltekkrdiaanefealfeeelekydplqeqleqslakqeellkeiqeaneefeqskksdseq..s...qrqreev 246
                     +q+lkdlkek+++dDi+++l+++kk+ +   ++++lf++elek++p+q+++ +s++ q +l+ke+++++ +++q+k+++seq  +   +rqr++v
      EEA21135.1 617 AQVLKDLKEKVHEDDISNVLILNKKS-LGNGQEQQLFQAELEKFRPYQNRIIKSNHTQGSLMKELTRTYGDLLQDKRVRSEQskYetiTRQRNTV 710
                     **************************.555777*************************************************753789******* PP

  ALIX_LYPXL_bnd 247 lqkleaaydkykelksnleeglkFYndltelleklqkkvkdfvfaRrtE 295
                     + ++++ y+++++l++++++++kFYn+++e++++l+k+v++fv++Rr+E
      EEA21135.1 711 MARYKKIYNAFRDLVTGVSQATKFYNEMQETVDNLRKNVDTFVNNRRSE 759
                     ***********************************************99 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.32
  ALIX_LYPXL_bnd 124 pssssaaasesveeqirklrsllekld 150
                      + +++ as +++++ +klr+l+e+l+
      EEA21135.1 768 EQDKNNSASGQEDREREKLRQLMERLS 794
                     333334457888999999999999886 PP

>> DUF3012  Protein of unknown function (DUF3012)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.1     0.025        74       5      12 ..     439     446 ..     438     457 .. 0.89
   2 ?    5.5   0.1    0.0059        18       7      21 ..     482     496 ..     479     499 .. 0.91

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.025
     DUF3012   5 eWCedMke 12 
                  WCe+M++
  EEA21135.1 439 RWCEEMAD 446
                 6*****98 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.0059
     DUF3012   7 CedMkeKpkgdWtan 21 
                 Ce+M+ K   dWt +
  EEA21135.1 482 CEKMRSKYGADWTQQ 496
                 *************76 PP

>> DUF2120  Uncharacterized protein conserved in archaea (DUF2120)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.1      0.11   3.4e+02      20      92 ..     457     532 ..     442     552 .. 0.70
   2 ?    8.2   0.6   0.00082       2.5      28      93 ..     725     789 ..     722     797 .. 0.78

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.11
     DUF2120  20 ldkeeiLivrgvsrkkeeleeleskleellekldaeevdleseeakkliekldesireveeieeevdaf...gler 92 
                 l++++ +iv + s+ + +l+  es+ e++ +k  a+  +  s + ++ +    +s+r++ +   ++d+     l++
  EEA21135.1 457 LQDSKAIIVDSLSQCTRQLDMEESVCEKMRSKYGADWTQQPSSRLTATLRGEIRSLRDTINEAGASDTQlnaTLKQ 532
                 6788899999999999999888888888888888776666666555555444456666666666666654444444 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.00082
     DUF2120  28 vrgvsrkkeeleeleskleellekldaeevdleseeakkliekldesireveeieeevdafglerl 93 
                 v gvs+ ++  +e+++++++l +++d+  v+    e+++l++++++   ++ + +e+ +   l +l
  EEA21135.1 725 VTGVSQATKFYNEMQETVDNLRKNVDT-FVNNRRSEGAQLLSQIEQDKNNSASGQEDREREKLRQL 789
                 89**********************997.57777789999****99987776666665555444444 PP

>> DUF148  Domain of unknown function DUF148
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.1      0.61   1.8e+03      29      60 ..     291     322 ..     290     323 .. 0.85
   2 ?    1.0   0.0      0.15   4.5e+02      12      40 ..     590     619 ..     583     635 .. 0.63
   3 ?    8.2   4.5   0.00088       2.6       2      97 ..     696     796 ..     695     799 .. 0.80

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.61
      DUF148  29 ekygvtdeykefeakvkaqkeevkknvtavis 60 
                 + + v+++ + + +++k +++ v+++v++ i+
  EEA21135.1 291 NSNLVSEDGASLMEEIKRHQAIVEEQVSTLIR 322
                 556788888899999************99986 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.15
      DUF148  12 nenltiaeieeqleawaeky.gvtdeykef 40 
                 + +l+ ae+ +++e++ +k   v+ e ++ 
  EEA21135.1 590 EGSLSVAEQITRVEELLKKLnLVKRERAQV 619
                 456777777777777777774344444444 PP

  == domain 3  score: 8.2 bits;  conditional E-value: 0.00088
      DUF148   2 arkeffaIlknenltiaeieeqleawaekygvtdeykefeakvkaqkeevkknvtavisnLssvqek.leaIldnkslTrkeqk....eaieelkkqyp 95 
                 +++++  I +++n  +a  ++  +a+       ++ ++f  ++++  ++++knv++ ++n  s  ++ l++I ++k+ +   q+    e++++l++ ++
  EEA21135.1 696 EQSKYETITRQRNTVMARYKKIYNAFRDLVTGVSQATKFYNEMQETVDNLRKNVDTFVNNRRSEGAQlLSQIEQDKNNSASGQEdrerEKLRQLMERLS 794
                 68899999999999999999999999998866678899999*******************99776663699******9987654111267777777666 PP

      DUF148  96 ke 97 
                  e
  EEA21135.1 795 TE 796
                 55 PP

>> PXA  PXA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   5.6     0.031        92      45     134 ..     707     793 ..     464     807 .. 0.86

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.031
         PXA  45 iralanrlkkvDlaqllltrlldlltshlrdyrqaeekvkskkae........eesdldlaakffalephpalsavlrd....ieeskeaelaylrslv 131
                   ++ +r kk+   +  +++l+  + + ++ y++ +e v++ +++         ++ ++l ++ ++            d    +++++++e++ lr+l+
  EEA21135.1 707 RNTVMARYKKIY--N-AFRDLVTGVSQATKFYNEMQETVDNLRKNvdtfvnnrRSEGAQLLSQIEQ------------DknnsASGQEDREREKLRQLM 790
                 445555555543..2.45899999999999999999999888776444442222222222222222............2334456789999******** PP

         PXA 132 erl 134
                 erl
  EEA21135.1 791 ERL 793
                 *98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1016 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1582  (0.0882369); expected 358.6 (0.02)
Passed bias filter:                      623  (0.0347482); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.49
# Mc/sec: 6224.22
//
Query:       EEA21136.1  [L=555]
Description: mitochondrial DnaJ chaperone (Mdj1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.8e-34  117.1   0.0      1e-33  116.5   0.0    1.3  1  DnaJ_C          DnaJ C terminal domain
    1.1e-21   76.7   2.2    2.2e-21   75.8   2.2    1.5  1  DnaJ            DnaJ domain
    9.9e-10   38.6  19.7      2e-09   37.6  19.7    1.6  1  DnaJ_CXXCXGXG   DnaJ central domain
     0.0027   17.6   3.1     0.0027   17.6   3.1    2.9  2  Anti-TRAP       Tryptophan RNA-binding attenuator protein inh


Domain annotation for each model (and alignments):
>> DnaJ_C  DnaJ C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.5   0.0   2.3e-37     1e-33       1     148 []     231     459 ..     231     459 .. 0.95

  Alignments for each domain:
  == domain 1  score: 116.5 bits;  conditional E-value: 2.3e-37
                 EEEEEEE-HHHHHH-.EEE.EEEE........................................................................TEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx.................................................................xxxxxxx RF
      DnaJ_C   1 ieveleisleelykGktkkikikrnvi.................................................................kkekktl 34 
                 iev+ +is+ e++kG+ k+i i+  v+                                                                 +++++t+
  EEA21136.1 231 IEVQTNISFMEAAKGTGKDIFITPLVEcqtctgsglkkgakrsqckscngsgtrvhfmqggfqlastcdvcngsgmvtprgsdcgtcsgqgvVRDRRTV 329
                 799*******************999999***************************************************************7667779* PP

                 EEEE-TT--TT-EEEETT-SS.......SS.....S---EEEEEEE---SS-EEETTEEEEEEEEEHHHHHHTEEEEEE-SS-EEEEEE...--TT-EE CS
                 xxxxxxxxxxxxxxxxxxxxx.......xxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxx RF
      DnaJ_C  35 evkipaGikdgqkirlegeGd.......eeg...gepGDlivtikvkphpvFkrkgndlyveveislaeallGgklevptldgkvklki...tqpgevl 120
                 +v+ip G++dg++ir++ eGd       +      ++GDl+v i+v+p+++F+r g+d++++++++l++allGg+++vptldg+vk+k+   t +g+ +
  EEA21136.1 330 HVDIPGGVEDGMRIRVAAEGDspptggaN-AgtrTQRGDLYVSIRVAPDHRFSRSGSDILYTASLPLTTALLGGEVTVPTLDGEVKVKVatgTGTGDRI 427
                 *********************99877653.14799*******************************************************9999***** PP

                 EETT-S-EET.......TEE--EEEEEEEE-- CS
                 xxxxxxxxxxx....xxxxxxxxxxxxxxxxx RF
      DnaJ_C 121 rikgkGmpklk....kpgkrGdlyvevkvefP 148
                 +++g+Gm kl     + +  Gdl ve+kv++P
  EEA21136.1 428 TLSGMGMRKLGgrgrSFSPTGDLRVEFKVQMP 459
                 **********9776666778***********9 PP

>> DnaJ  DnaJ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.8   2.2   4.8e-25   2.2e-21       1      63 []      83     144 ..      83     144 .. 0.99

  Alignments for each domain:
  == domain 1  score: 75.8 bits;  conditional E-value: 4.8e-25
                 HHHHHHTSSTTG-HHHHHHHHHHHHHHHSTTTSCCHHHHHHHHHHHHHHHHHHTSHHHHHHHH CS
        DnaJ   1 dyYeiLgvskdasedeIkkaYrklalkyHPDknpkdpeaeekFkeineAyevLsdpekRkqYD 63 
                 d+Y++Lgv+k+as+++IkkaY+ +a+k+HPD n k+p a++kF e + Aye Lsd++k+++YD
  EEA21136.1  83 DPYKVLGVDKNASAADIKKAYYGMAKKFHPDTN-KEPGAKDKFAEAQSAYELLSDAKKKEAYD 144
                 78*******************************.****************************9 PP

>> DnaJ_CXXCXGXG  DnaJ central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.6  19.7   4.6e-13     2e-09       1      67 []     258     321 ..     258     321 .. 0.82

  Alignments for each domain:
  == domain 1  score: 37.6 bits;  conditional E-value: 4.6e-13
  DnaJ_CXXCXGXG   1 CkkCkGsgakkgk.kktCktCkGsGvvreeqktlgpfvqqsqstCpeCeGtGkvikekdkCkkCkGkg 67 
                    C++C Gsg kkg+ +++Ck+C+GsG+ ++ +    +   q  stC+ C+G+G v+ + + C +C+G+g
     EEA21136.1 258 CQTCTGSGLKKGAkRSQCKSCNGSGTRVHFM----QGGFQLASTCDVCNGSGMVTPRGSDCGTCSGQG 321
                    *********99554999********533333....22235789************9999*******97 PP

>> Anti-TRAP  Tryptophan RNA-binding attenuator protein inhibitory protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   6.3     0.017        74      12      40 ..     257     282 ..     255     290 .. 0.85
   2 !   17.6   3.1   6.1e-07    0.0027       9      42 ..     294     323 ..     288     327 .. 0.91

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.017
                 E-TTTTTTSEETTE......E-TTTTTSS CS
   Anti-TRAP  12 kCdaCngsGkiepeeprasleCPkCsGkg 40 
                 +C++C gsG  +++ +    +C  C+G g
  EEA21136.1 257 ECQTCTGSGLKKGA-K--RSQCKSCNGSG 282
                 7************9.3..34899999987 PP

  == domain 2  score: 17.6 bits;  conditional E-value: 6.1e-07
                 CEEE-TTTTTTSEETTE......E-TTTTTSSEE CS
   Anti-TRAP   9 LEtkCdaCngsGkiepeeprasleCPkCsGkgli 42 
                 L  +Cd CngsG + p     + +C  CsG+g++
  EEA21136.1 294 LASTCDVCNGSGMVTPR----GSDCGTCSGQGVV 323
                 7789************9....88*********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (555 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       734  (0.0409393); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.44u 0.21s 00:00:00.65 Elapsed: 00:00:00.39
# Mc/sec: 4284.83
//
Query:       EEA21137.1  [L=1116]
Description: mitochondrial serine protease Pim1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.4e-62  208.5   0.0    1.3e-61  207.8   0.0    1.4  1  Lon_C           Lon protease (S16) C-terminal proteolytic dom
    7.3e-35  120.7   0.0    1.5e-34  119.7   0.0    1.6  1  LON_substr_bdg  ATP-dependent protease La (LON) substrate-bin
      9e-22   77.9   0.0    1.8e-21   76.9   0.0    1.6  1  AAA             ATPase family associated with various cellula
    9.7e-08   32.1   0.0    2.1e-07   31.0   0.0    1.6  1  AAA_5           AAA domain (dynein-related subfamily)
    4.6e-06   25.8   0.3    9.6e-06   24.7   0.0    1.6  2  AAA_PrkA        PrkA AAA domain
    7.9e-06   26.1   0.0    2.5e-05   24.5   0.0    1.8  1  AAA_2           AAA domain (Cdc48 subfamily)
    1.1e-05   25.8   0.1    0.00013   22.3   0.1    2.3  1  AAA_22          AAA domain
    1.5e-05   24.8   0.0    3.5e-05   23.6   0.0    1.6  1  ChlI            Subunit ChlI of Mg-chelatase
    0.00015   22.2   1.3    0.00059   20.2   0.1    2.5  2  AAA_16          AAA ATPase domain
    0.00018   21.3   0.0    0.00053   19.8   0.0    1.8  1  RuvB_N          Holliday junction DNA helicase RuvB P-loop do
     0.0024   18.4   0.3      0.027   15.0   0.0    2.8  3  AAA_18          AAA domain
     0.0055   16.7   0.0      0.013   15.5   0.0    1.6  1  AAA_14          AAA domain
  ------ inclusion threshold ------
      0.023   14.4   0.0      0.051   13.3   0.0    1.5  1  AAA_30          AAA domain
      0.026   14.3   0.0      0.059   13.1   0.0    1.5  1  IstB_IS21       IstB-like ATP binding protein
      0.038   13.9   0.1       0.56   10.1   0.0    2.7  3  NTPase_1        NTPase
      0.048   14.0   0.0       0.21   12.0   0.0    2.2  1  RNA_helicase    RNA helicase
      0.078   12.9   0.2       0.23   11.4   0.0    1.8  1  RsgA_GTPase     RsgA GTPase
      0.079   13.2   0.2       0.31   11.3   0.1    2.0  2  CHASE8          Periplasmic sensor domain
       0.11   13.0   1.2       0.43   11.1   0.1    2.5  2  ABC_tran        ABC transporter
       0.13   11.8   0.1       0.35   10.4   0.0    1.7  2  AAA_7           P-loop containing dynein motor region
       0.13   11.1   5.0       0.26   10.1   5.0    1.4  1  Apt1            Golgi-body localisation protein domain
        3.2    6.4   7.9        5.5    5.6   7.9    1.2  1  Presenilin      Presenilin


Domain annotation for each model (and alignments):
>> Lon_C  Lon protease (S16) C-terminal proteolytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  207.8   0.0   1.6e-64   1.3e-61       2     203 ..     876    1082 ..     875    1084 .. 0.95

  Alignments for each domain:
  == domain 1  score: 207.8 bits;  conditional E-value: 1.6e-64
                  E-TTTTHHHH-S-SS--SSSSS--BSSEEEEEEEETTEEEEEEEEEE.....EESS-S-EEEEES--HHHHHHHHHHHHHHTSS-GGGSS-SS-TTT CS
       Lon_C    2 vtakeleellGkkrfrseeaekedqvGvvtGlawtevGGdlltieav.....llpgkgklkltGklgdvmkesaqaalsyvrsraeelgidkevfek 93  
                  ++++ l++++G ++f+s++       Gv++Glawt++GG  l++e+      + + +  +++tG+l +vmkes q+a+s+ +s +++   ++ +fek
  EEA21137.1  876 ISKEVLKDYVGPPVFTSDRLYDVFPPGVTMGLAWTSMGGAALYVESIlenalTYDSRPGFETTGNLMNVMKESTQIAYSFSKSVMAQDFPENRFFEK 972 
                  78899***************************************97511111566899*************************************** PP

                  -EEEEEE-S-B-GGGGGGGHHHHHHHHHHHHTS--B-TTBEE--EE-TT-BEE--S-HHHHHHHHHHTT-SBEEEEGGGGGGTTTS-HHHHTS-B-- CS
       Lon_C   94 kdihihvPeGavPkdGPsaGvtlatalvslltgkkvrkdvamtGeitLrGrvlpiGGlkekllaakragikkvilPkenekdlediPeevreeleii 190 
                  +++h+h PeGav kdGPsaG+t+at+l+sl  +++ +  +amtGe+t++G+vl iGGl+ek++aa+rag kk+++P +n +d  ++Pe+++e++e +
  EEA21137.1  973 ARVHLHCPEGAVQKDGPSAGITMATSLLSLALNHPLDPTIAMTGELTVTGKVLRIGGLREKTVAARRAGAKKILFPADNMSDWLELPENIKEGIEGH 1069
                  ************************************************************************************************* PP

                  EESBHHHHHHHHB CS
       Lon_C  191 lveevdevlkaal 203 
                  +v+++++v++ ++
  EEA21137.1 1070 PVNWYSDVFNIVF 1082
                  ********98765 PP

>> LON_substr_bdg  ATP-dependent protease La (LON) substrate-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.7   0.0   1.8e-37   1.5e-34       4     208 .]     200     456 ..     197     456 .. 0.90

  Alignments for each domain:
  == domain 1  score: 119.7 bits;  conditional E-value: 1.8e-37
  LON_substr_bdg   4 llpldnkvlfPgitlpltvsrpksiaaierlldkdkpyigvflvkesqkdaide.esiselysvGtvarIvqil....rlddgrikvvlegleRv 93 
                      +p+ +++lfPg++  +tv++p+++aai++++++++py+g fl  +++ ++ d+ e+ +++y+vG++a+I+       ++++g +  vl++++R+
      EEA21137.1 200 SIPIARRPLFPGFYKAITVKDPNVAAAIQEMMKRGQPYVGAFLF-KNDDADGDIiENMDDVYDVGVFAQITSTYplstKDGEGGLTAVLYPHRRI 293
                     57999***************************************.555555788999**************9888886777899*********** PP

  LON_substr_bdg  94 kikkl.eke................................................keegylvaeveiieddsepedsdslqkelkalvqeiie 139
                     ki +l  +                                                  ++ ++ a+ve++    ++e +d+++ +++a ++ei++
      EEA21137.1 294 KISSLlAPNdparnstvdqpitkdtyekkgdvvasfeegaveappkevyhyeptsflRKHAVTLANVENL----TEEPFDKKSPVIRAVTSEIVN 384
                     **99955548899999999999999999999999999999999888888888888887788889999999....9999999999*********** PP

  LON_substr_bdg 140 kikks.....larellkllleielllkyedlenpyrLadlvaailpfsneekqelLeeldvedRlkkvlelLkr 208
                       k++     l+r +++ +  +   +++   ++p++Lad++aa+ +++++e qe+Le++++e+Rl k+l  Lk+
      EEA21137.1 385 VCKEIvqfnpLFRDQISAFATDHFPGNLG--DEPGKLADFAAAVASGDSQEVQEVLEAMNIEERLPKALVVLKK 456
                     ****555777*********9888888888..8999**********************************99985 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.9   0.0   2.3e-24   1.8e-21       1     126 [.     607     743 ..     607     749 .. 0.94

  Alignments for each domain:
  == domain 1  score: 76.9 bits;  conditional E-value: 2.3e-24
                 EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSS.........STTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHH CS
         AAA   1 vllyGppGtGKTllakavakelgvefleisgsellsk.........yvgesekkirelfkeakekakpsilfiDEidalaksrsgseseeeervvnqLl 90 
                 ++l+GppG+GKT++ k++a+ l+++++++s+  l++          yvg+ + +i + +k++++++    ++iDE+d++++         + + +++Ll
  EEA21137.1 607 LCLVGPPGVGKTSIGKSIARALNRQYYRFSVGGLTDVaeikghrrtYVGALPGRIIQALKKCQTEN--PLILIDEVDKIGRGH-------QGDPASALL 696
                 58*********************99999999999966889999999*****************998..9**********8888.......999****** PP

                 HHHHHTTTS............SSTEEEEEEESSGGGSTHHHHSTTSSE CS
         AAA  91 teldgvkkk............eskvivigatnrpdkldpallrgRfdr 126
                 + ld ++++             skv++++++n  d+++++ll +R++ 
  EEA21137.1 697 ELLDPEQNSsfldhymdvpvdLSKVLFVCTANVTDTIPRPLL-DRMEL 743
                 *********************999******************.9*986 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.0   0.0   2.5e-10   2.1e-07       2     124 ..     607     731 ..     606     741 .. 0.71

  Alignments for each domain:
  == domain 1  score: 31.0 bits;  conditional E-value: 2.5e-10
                 EEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--..........--------.G-SEEEEESGGG--H....HHHHHHHHHHHSSEE CS
       AAA_5   2 vlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreikngtts.lvdsplvraar.egeilvlDEveraes....evlnsLlslleerrl 94 
                 ++LvGppG+gK+++ +++a+alnr++        t  +++kg+r++  g    +  ++l+ +++ e  ++++DEv+++ +    + +++Ll ll+ ++ 
  EEA21137.1 607 LCLVGPPGVGKTSIGKSIARALNRQYYRFSVGGLTDVAEIKGHRRTYVGALPgRIIQALK-KCQtENPLILIDEVDKIGRghqgDPASALLELLDPEQN 704
                 79*******************************************864444303334444.4446999********98651222556788888887766 PP

                 E..-SSSEEE---......-EEEEEESS-- CS
       AAA_5  95 lleeggelvkaknddllerfrviatanpld 124
                 +   ++++++++ d  l+++ ++ tan  d
  EEA21137.1 705 S-SFLDHYMDVPVD--LSKVLFVCTANVTD 731
                 5.445555555543..34477777777766 PP

>> AAA_PrkA  PrkA AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.1       4.7   3.8e+03      88     115 ..     489     516 ..     485     525 .. 0.77
   2 !   24.7   0.0   1.2e-08   9.6e-06      55     114 ..     571     630 ..     559     642 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 4.7
    AAA_PrkA  88 kqilyllGPvggGksslverlkklleaa 115
                 k i   lG  + Gk  lve++k+  e+ 
  EEA21137.1 489 KGIKRELGIESDGKDKLVEKFKEKAEKL 516
                 556666788899999****999988876 PP

  == domain 2  score: 24.7 bits;  conditional E-value: 1.2e-08
    AAA_PrkA  55 kypafeedffGleetiekiveyfraaaqrleerkqilyllGPvggGksslverlkkllea 114
                   ++++ed +Gl+++ ++i+e++     r+ ++ +il l+GP g Gk+s+ +++ ++l+ 
  EEA21137.1 571 AMSVLDEDHYGLKDVKDRILEFIAVGKLRGSVEGKILCLVGPPGVGKTSIGKSIARALNR 630
                 467899************************************************999976 PP

>> AAA_2  AAA domain (Cdc48 subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.5   0.0     3e-08   2.5e-05       7     132 ..     608     732 ..     603     761 .. 0.76

  Alignments for each domain:
  == domain 1  score: 24.5 bits;  conditional E-value: 3e-08
                 EEE--TTSSHHHHHHHHHHHTT-....-EEEEEGGG---.----THHHHHHHHH..TTT-HHHHTTSEEEEETGGG-------------HHHHHHHHHH CS
       AAA_2   7 lllgptgvGktelakalaellfvkkekkliradaselle.eeevehlvsrliga..ppgyvgaeegGivllDEidKihpkessgadvSregVqrdLLqi 102
                  l+gp gvGkt + k++a+ l+ ++  ++ +   ++++e +   +++v  l g   +   + + e+  +l+DE+dKi +         + +   +LL +
  EEA21137.1 608 CLVGPPGVGKTSIGKSIARALN-RQYYRFSVGGLTDVAEiKGHRRTYVGALPGRiiQALKKCQTENPLILIDEVDKIGR-------GHQGDPASALLEL 698
                 478*******************.78888888888888884444445555554431133333444555************.......223467889**** PP

                 HH--EE-...----.--EE-TT-EEEEEE--TTH CS
       AAA_2 103 leggtlt...dkqg.rkvdtknilfImtgafgss 132
                 l+  + +   d++   +vd +++lf++t ++  +
  EEA21137.1 699 LDPEQNSsflDHYMdVPVDLSKVLFVCTANVTDT 732
                 *95444444466666***************9765 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.3   0.1   1.6e-07   0.00013       5     110 ..     604     697 ..     601     727 .. 0.79

  Alignments for each domain:
  == domain 1  score: 22.3 bits;  conditional E-value: 1.6e-07
      AAA_22   5 agilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelkaerlsseellealeqalrarav.ielliiDEaqh 102
                  +il+++G++G+GKT   + +++ l         +++++++ + ++t       +++++ g+++ +      +l  ++ qal+++++  +l++iDE+++
  EEA21137.1 604 GKILCLVGPPGVGKTSIGKSIARAL---------NRQYYRFSVGGLT-------DVAEIKGHRRTY----VGALPGRIIQALKKCQTeNPLILIDEVDK 682
                 689**********************.........9998888888888.......556666654444....667889*********************** PP

      AAA_22 103 lr...s....eeale 110
                 +    +     ++le
  EEA21137.1 683 IGrghQgdpaSALLE 697
                 965542444333333 PP

>> ChlI  Subunit ChlI of Mg-chelatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.6   0.0   4.3e-08   3.5e-05      40     121 .]     970    1051 ..     926    1051 .. 0.76

  Alignments for each domain:
  == domain 1  score: 23.6 bits;  conditional E-value: 4.3e-08
        ChlI   40 fpakkitvnLaPadlkkeGsafDLpiAigilaaleqieaeeetlflGeLsldGslrpvkgvlpialaakkegikkvivpken 121 
                  f++ ++ +      ++k+G++  +++A ++l+ + + + + ++ + GeL  +G++ ++ g+ + ++aa+++g kk++ p++n
  EEA21137.1  970 FEKARVHLHCPEGAVQKDGPSAGITMATSLLSLALNHPLDPTIAMTGELTVTGKVLRIGGLREKTVAARRAGAKKILFPADN 1051
                  4444555555556799***************************************************************998 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.1       8.7   7.1e+03      80     107 ..     457     493 ..     427     539 .. 0.55
   2 !   20.2   0.1   7.3e-07   0.00059      24      76 ..     604     657 ..     586     699 .. 0.73

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 8.7
      AAA_16  80 ellrqlldeaesaeleawrekleeala.........a 107
                 el+++ l+ + s+++ea  +k ++++           
  EEA21137.1 457 ELINAQLQSKISKDVEAKIQKRQREYWlmeqmkgikR 493
                 5555555555555555555555555543333332221 PP

  == domain 2  score: 20.2 bits;  conditional E-value: 7.3e-07
      AAA_16  24 pelvllsGesGvGKsslvrellralekdggiflrgkcdql.esaipysalaqal 76 
                 + ++ l+G++GvGK+s+ ++++ral++++  f  g  ++  e + ++ +++ al
  EEA21137.1 604 GKILCLVGPPGVGKTSIGKSIARALNRQYYRFSVGGLTDVaEIKGHRRTYVGAL 657
                 3899************************88886666666522222222344444 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.0   6.5e-07   0.00053       7      62 ..     577     633 ..     573     649 .. 0.87

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 6.5e-07
      RuvB_N   7 eeyigqekvkeklkifieaakkreealdhvl.lyGpPGlGkttlakiiakelgvklk 62 
                 e++ g ++vk+++  fi+  k r++    +l l+GpPG+Gkt++ k ia+ l+ +  
  EEA21137.1 577 EDHYGLKDVKDRILEFIAVGKLRGSVEGKILcLVGPPGVGKTSIGKSIARALNRQYY 633
                 578899********************99998689****************9998765 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.1       6.5   5.3e+03      38      69 ..     484     514 ..     441     534 .. 0.56
   2 !   15.0   0.0   3.3e-05     0.027       2      25 ..     608     637 ..     607     683 .. 0.82
   3 ?   -1.2   0.0       3.4   2.7e+03      77     103 ..     959     981 ..     922     985 .. 0.68

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 6.5
      AAA_18  38 llevdpealdeskrldedkldklldaleenss 69 
                 l e+ +  +++++ ++ d  dkl+++++e ++
  EEA21137.1 484 LMEQMKG-IKRELGIESDGKDKLVEKFKEKAE 514
                 2222222.444555555555555555555544 PP

  == domain 2  score: 15.0 bits;  conditional E-value: 3.3e-05
      AAA_18   2 lltGtpGvGKttlakeLskrlgf......g 25 
                 +l G+pGvGKt+++k +++ l+       +
  EEA21137.1 608 CLVGPPGVGKTSIGKSIARALNRqyyrfsV 637
                 799***************998555555443 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 3.4
      AAA_18  77 lvidghlaeleseaakdikkvvLtasp 103
                 +  ++++++ ++e+a+    v+L++++
  EEA21137.1 959 VMAQDFPENRFFEKAR----VHLHCPE 981
                 3334444444444444....*****97 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   1.6e-05     0.013       2      77 ..     604     689 ..     603     730 .. 0.67

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1.6e-05
      AAA_14   2 rkilvitGaRrvGKTtllkqlikellvkkesilyinldderd....kkladpe........kllelileklkeekktylflDEiqev.....p 77 
                 +kil+++G+  vGKT + k +++ l    +++  +++   +d    k ++  +        ++++++++  +  ++ ++++DE+ ++      
  EEA21137.1 604 GKILCLVGPPGVGKTSIGKSIARALN---RQYYRFSVGGLTDvaeiKGHR--RtyvgalpgRIIQALKKC-Q-TENPLILIDEVDKIgrghqG 689
                 699*******************9988...888888877766643332222..124563333444444443.3.5899*******998555551 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   6.3e-05     0.051      19      97 ..     605     680 ..     595     698 .. 0.67

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 6.3e-05
      AAA_30  19 rvavltGpAGtGKttalkalreaweaag..grviglAptgkaAkvLaeelgi.eastiakllkrlkgrarlepgtllivDEa 97 
                 ++ +l+Gp+G GKt + k++++a++++   ++v gl+  ++     ++ +g+ +++ i+ l k ++      ++ l+++DE+
  EEA21137.1 605 KILCLVGPPGVGKTSIGKSIARALNRQYyrFSVGGLTDVAEIKGHRRTYVGAlPGRIIQALKKCQT------ENPLILIDEV 680
                 5889****************9999999612555555555554444444555324444444442222......2356666665 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   7.2e-05     0.059      48     117 ..     605     680 ..     570     705 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 7.2e-05
   IstB_IS21  48 enivllGpsGvGKshlaialgveavraglsvlfvrvedLveelkrarrd......gklaralkrllkv.dllilDdl 117
                 + ++l+Gp+GvGK+ +  +++++  r+ ++ +   ++d+ +e+k +rr       g++ +alk+++    l+++D++
  EEA21137.1 605 KILCLVGPPGVGKTSIGKSIARALNRQYYRFSVGGLTDV-AEIKGHRRTyvgalpGRIIQALKKCQTEnPLILIDEV 680
                 5689******************99999988877777774.3444444432222225555555555444245566665 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       5.3   4.3e+03     112     150 ..     221     262 ..     218     269 .. 0.69
   2 ?   10.1   0.0   0.00068      0.56       3      33 ..     608     640 ..     606     655 .. 0.75
   3 ?    0.1   0.0      0.82   6.7e+02      84     106 ..     660     682 ..     647     689 .. 0.83

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 5.3
                 HHHHHHHHHHHTTTSEEEEE--SS-...-SHHHHHHHT-TT- CS
    NTPase_1 112 kkfkeaveevLksekpvlavihrrk...dlalveeirerkdv 150
                 ++++ a++e++k+++p ++ +  ++   d +++e++ +  dv
  EEA21137.1 221 PNVAAAIQEMMKRGQPYVGAFLFKNddaDGDIIENMDDVYDV 262
                 5788999*****999999987666544555566665555555 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00068
                 EEE--TTSSHHHHHHHHHHHH.....GGGEEEE CS
    NTPase_1   3 fiTGppGvGKtTlvkkvlellkss..gvkvgGf 33 
                 ++ GppGvGKt + k ++++l+++   ++vgG+
  EEA21137.1 608 CLVGPPGVGKTSIGKSIARALNRQyyRFSVGGL 640
                 688******************988334456665 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.82
                 HHHHHHHHHHHHH-EEEE---ST CS
    NTPase_1  84 lalealrkalseadviviDEiGk 106
                  +++al+k ++e+ +i+iDE+ k
  EEA21137.1 660 RIIQALKKCQTENPLILIDEVDK 682
                 57889999999999******955 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   0.00026      0.21       1      27 [.     607     639 ..     607     698 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00026
  RNA_helicase   1 iwlyGpsgeGKStlakeLakallkkl......k 27 
                   ++l+Gp+g+GK+++ k++a+al +++      +
    EEA21137.1 607 LCLVGPPGVGKTSIGKSIARALNRQYyrfsvgG 639
                   589*******************98875555550 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00028      0.23      90     123 ..     595     628 ..     574     637 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00028
                  HHHHHHHCTTSEEEEECSTTSSHHHHHHHHCTT- CS
  RsgA_GTPase  90 leelkellkdktsvlvGqSGvGKStLinallpel 123
                  + +l+  +++k+ +lvG+ GvGK+++ ++++  l
   EEA21137.1 595 VGKLRGSVEGKILCLVGPPGVGKTSIGKSIARAL 628
                  66899999*****************988887655 PP

>> CHASE8  Periplasmic sensor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       6.6   5.4e+03      51      73 ..     319     343 ..     317     364 .. 0.71
   2 ?   11.3   0.1   0.00038      0.31      21      83 ..     423     486 ..     420     502 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 6.6
      CHASE8  51 ydaegkllaeyaresseak..eele 73 
                 y+++g + a++++++ ea+  e ++
  EEA21137.1 319 YEKKGDVVASFEEGAVEAPpkEVYH 343
                 7899*******99998887533333 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00038
      CHASE8  21 eAAlvFeDaaaAreiLaaLkaepeiaaaavydaegkllaeyaresseak.eeleallaslllpe 83 
                  AA++ +D+++ +e+L+a++ e+ + +a v+ +++ + a+ +++ s++   +++++++++ l+e
  EEA21137.1 423 AAAVASGDSQEVQEVLEAMNIEERLPKALVVLKKELINAQLQSKISKDVeAKIQKRQREYWLME 486
                 79*****************************999999998888876665466666666555554 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.2       4.8   3.9e+03      68     100 ..     461     503 ..     426     534 .. 0.47
   2 ?   11.1   0.1   0.00053      0.43      10      36 ..     603     629 ..     600     654 .. 0.91

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 4.8
                 --S-TTSBHHHH............HHHTCHHHHHHHSTTGGTTCB CS
                 xxxxxxxxxxxx............xxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  68 pqlfpeltvren............esdeeiekalsklglkelkdt 100
                 +ql+++++  +             +  e+++ + ++lg++ + ++
  EEA21137.1 461 AQLQSKIS--KDveakiqkrqreyWLMEQMKGIKRELGIESDGKD 503
                 33333332..11223343333333333334444444444333333 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00053
                 TTSEEEEEESTTSSHHHHHHHHTTSS- CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  10 egekvaivGenGaGKStLlkllagllk 36 
                 eg+++ +vG+ G GK+++ k +a+ l+
  EEA21137.1 603 EGKILCLVGPPGVGKTSIGKSIARALN 629
                 799*******************99876 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0       5.7   4.6e+03      45      89 ..     429     474 ..     425     483 .. 0.54
   2 ?   10.4   0.0   0.00043      0.35      34      63 ..     605     634 ..     601     642 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 5.7
       AAA_7  45 GKtviikdllkkld.kekylsltinfsaqtsanqlqdiiesklekr 89 
                 G +  ++++l++++ +e++  + + +++    +qlq+ i + +e +
  EEA21137.1 429 GDSQEVQEVLEAMNiEERLPKALVVLKKELINAQLQSKISKDVEAK 474
                 5566666666666634444444455566666666666665554433 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00043
       AAA_7  34 kpvllvGptGtGKtviikdllkkldkekyl 63 
                 k ++lvGp G+GKt+i k++ ++l+++ y 
  EEA21137.1 605 KILCLVGPPGVGKTSIGKSIARALNRQYYR 634
                 66789*******************977665 PP

>> Apt1  Golgi-body localisation protein domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   5.0   0.00032      0.26     312     412 ..      66     237 ..      44     240 .. 0.49

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00032
        Apt1 312 ss..seeddesdeesessssssssssssassssssssrssslelrlkptsstssssssessssssskkrsseesslessaserv.............ks 395
                  +  ++  ++ +++  ++++ ++++ +s+++s + +++++s + +++p+ +  +s+++++++ +++kk +s+  +++s+ s++              + 
  EEA21137.1  66 APpsEDAPENAENNDGAEGKDTTKQVDSRRKSGDATDKQGSTQTTDTPSRRRDKSNAEKEEQAEVTKKGESQ--QAKSRDSKADssspspipvsgggG- 161
                 223211111111111222222233333333333333333333333333322222222222222222221111..111111111111122334544441. PP

        Apt1 396 sr............................................................asddleemksRasky 412
                  +                                                                ++em++R + y
  EEA21137.1 162 -SeskpsggngnddggrrgrkgekslqkpfipdvypqvmsipiarrplfpgfykaitvkdpnVAAAIQEMMKRGQPY 237
                 .0445566667777777888888899999999999999999999999999999999999999889999999997766 PP

>> Presenilin  Presenilin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   7.9    0.0067       5.5     209     310 ..      43     145 ..      38     179 .. 0.44

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0067
  Presenilin 209 eifpaLiYsatvvvlaaeekkaevaeseeeeeaekkkeeasesskeeesee.esseksaqsseseeeseeesseaessaeesseekeseessesseeee 306
                 +ifp    +++++++++++ k+++ +se++ e+ ++++ a+ ++++++ ++ ++s + + ++ s++++++ s++ ++s++e++e++e +++ es+++++
  EEA21137.1  43 PIFPTPTIASRAFTSSRTSYKEKAPPSEDAPENAENNDGAEGKDTTKQVDSrRKSGDATDKQGSTQTTDTPSRRRDKSNAEKEEQAEVTKKGESQQAKS 141
                 556655555666655444443333333332222222222222222222222022222222222333333333333333333333333333333333322 PP

  Presenilin 307 eeee 310
                 ++++
  EEA21137.1 142 RDSK 145
                 2222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1116 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1326  (0.0739584); expected 358.6 (0.02)
Passed bias filter:                      604  (0.0336884); expected 358.6 (0.02)
Passed Vit filter:                       112  (0.00624686); expected 17.9 (0.001)
Passed Fwd filter:                        24  (0.00133861); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              22  [number of targets reported over threshold]
# CPU time: 0.83u 0.30s 00:00:01.12 Elapsed: 00:00:00.54
# Mc/sec: 6232.98
//
Query:       EEA21138.1  [L=1072]
Description: mitochondrial serine protease Pim1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      7e-57  192.3   0.0    1.3e-56  191.4   0.0    1.4  1  Lon_C           Lon protease (S16) C-terminal proteolytic dom
    6.8e-35  120.8   0.0    1.4e-34  119.8   0.0    1.5  1  LON_substr_bdg  ATP-dependent protease La (LON) substrate-bin
    8.5e-22   78.0   0.0    1.7e-21   77.0   0.0    1.6  1  AAA             ATPase family associated with various cellula
      1e-07   32.0   0.0    1.9e-07   31.1   0.0    1.5  1  AAA_5           AAA domain (dynein-related subfamily)
    4.1e-06   26.0   0.2    9.1e-06   24.8   0.0    1.6  2  AAA_PrkA        PrkA AAA domain
    7.6e-06   26.1   0.0    2.3e-05   24.6   0.0    1.8  1  AAA_2           AAA domain (Cdc48 subfamily)
      1e-05   25.9   0.1    0.00012   22.3   0.1    2.3  1  AAA_22          AAA domain
    1.4e-05   24.9   0.0    3.3e-05   23.7   0.0    1.6  1  ChlI            Subunit ChlI of Mg-chelatase
    0.00015   22.2   1.4    0.00057   20.3   0.1    2.5  2  AAA_16          AAA ATPase domain
    0.00017   21.4   0.0    0.00051   19.8   0.0    1.8  1  RuvB_N          Holliday junction DNA helicase RuvB P-loop do
     0.0024   18.4   0.3      0.026   15.1   0.0    2.8  3  AAA_18          AAA domain
     0.0055   16.7   0.0      0.012   15.6   0.0    1.6  1  AAA_14          AAA domain
  ------ inclusion threshold ------
      0.022   14.5   0.0      0.049   13.4   0.0    1.5  1  AAA_30          AAA domain
      0.025   14.3   0.0      0.056   13.2   0.0    1.5  1  IstB_IS21       IstB-like ATP binding protein
       0.03   14.6   0.2      0.069   13.4   0.2    1.6  1  DUF4276         Domain of unknown function (DUF4276)
      0.034   14.1   0.1       0.53   10.2   0.0    2.7  3  NTPase_1        NTPase
      0.064   13.6   0.0        0.2   12.1   0.0    1.9  1  RNA_helicase    RNA helicase
      0.075   13.3   0.2        0.3   11.4   0.1    2.0  2  CHASE8          Periplasmic sensor domain
      0.077   12.9   0.3       0.22   11.4   0.0    1.8  1  RsgA_GTPase     RsgA GTPase
       0.11   13.0   1.3       0.41   11.1   0.1    2.5  2  ABC_tran        ABC transporter
       0.12   11.9   0.1       0.33   10.4   0.0    1.7  2  AAA_7           P-loop containing dynein motor region
       0.12   11.2   5.0       0.24   10.2   5.0    1.4  1  Apt1            Golgi-body localisation protein domain
        3.1    6.5   7.9        5.2    5.7   7.9    1.2  1  Presenilin      Presenilin


Domain annotation for each model (and alignments):
>> Lon_C  Lon protease (S16) C-terminal proteolytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  191.4   0.0   1.7e-59   1.3e-56       2     182 ..     876    1061 ..     875    1067 .. 0.94

  Alignments for each domain:
  == domain 1  score: 191.4 bits;  conditional E-value: 1.7e-59
                  E-TTTTHHHH-S-SS--SSSSS--BSSEEEEEEEETTEEEEEEEEEE.....EESS-S-EEEEES--HHHHHHHHHHHHHHTSS-GGGSS-SS-TTT CS
       Lon_C    2 vtakeleellGkkrfrseeaekedqvGvvtGlawtevGGdlltieav.....llpgkgklkltGklgdvmkesaqaalsyvrsraeelgidkevfek 93  
                  ++++ l++++G ++f+s++       Gv++Glawt++GG  l++e+      + + +  +++tG+l +vmkes q+a+s+ +s +++   ++ +fek
  EEA21138.1  876 ISKEVLKDYVGPPVFTSDRLYDVFPPGVTMGLAWTSMGGAALYVESIlenalTYDSRPGFETTGNLMNVMKESTQIAYSFSKSVMAQDFPENRFFEK 972 
                  78899***************************************97511111566899*************************************** PP

                  -EEEEEE-S-B-GGGGGGGHHHHHHHHHHHHTS--B-TTBEE--EE-TT-BEE--S-HHHHHHHHHHTT-SBEEEEGGGGGGTTTS-HH CS
       Lon_C   94 kdihihvPeGavPkdGPsaGvtlatalvslltgkkvrkdvamtGeitLrGrvlpiGGlkekllaakragikkvilPkenekdlediPee 182 
                  +++h+h PeGav kdGPsaG+t+at+l+sl  +++ +  +amtGe+t++G+vl iGGl+ek++aa+rag kk+++P +n +d  ++Pe 
  EEA21138.1  973 ARVHLHCPEGAVQKDGPSAGITMATSLLSLALNHPLDPTIAMTGELTVTGKVLRIGGLREKTVAARRAGAKKILFPADNMSDWLELPEV 1061
                  ***************************************************************************************85 PP

>> LON_substr_bdg  ATP-dependent protease La (LON) substrate-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.8   0.0   1.8e-37   1.4e-34       4     208 .]     200     456 ..     197     456 .. 0.90

  Alignments for each domain:
  == domain 1  score: 119.8 bits;  conditional E-value: 1.8e-37
  LON_substr_bdg   4 llpldnkvlfPgitlpltvsrpksiaaierlldkdkpyigvflvkesqkdaide.esiselysvGtvarIvqil....rlddgrikvvlegleRv 93 
                      +p+ +++lfPg++  +tv++p+++aai++++++++py+g fl  +++ ++ d+ e+ +++y+vG++a+I+       ++++g +  vl++++R+
      EEA21138.1 200 SIPIARRPLFPGFYKAITVKDPNVAAAIQEMMKRGQPYVGAFLF-KNDDADGDIiENMDDVYDVGVFAQITSTYplstKDGEGGLTAVLYPHRRI 293
                     57999***************************************.555555788999**************9888886777899*********** PP

  LON_substr_bdg  94 kikkl.eke................................................keegylvaeveiieddsepedsdslqkelkalvqeiie 139
                     ki +l  +                                                  ++ ++ a+ve++    ++e +d+++ +++a ++ei++
      EEA21138.1 294 KISSLlAPNdparnstvdqpitkdtyekkgdvvasfeegaveappkevyhyeptsflRKHAVTLANVENL----TEEPFDKKSPVIRAVTSEIVN 384
                     **99955548899999999999999999999999999999999888888888888887788889999999....9999999999*********** PP

  LON_substr_bdg 140 kikks.....larellkllleielllkyedlenpyrLadlvaailpfsneekqelLeeldvedRlkkvlelLkr 208
                       k++     l+r +++ +  +   +++   ++p++Lad++aa+ +++++e qe+Le++++e+Rl k+l  Lk+
      EEA21138.1 385 VCKEIvqfnpLFRDQISAFATDHFPGNLG--DEPGKLADFAAAVASGDSQEVQEVLEAMNIEERLPKALVVLKK 456
                     ****555777*********9888888888..8999**********************************99985 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.0   0.0   2.2e-24   1.7e-21       1     126 [.     607     743 ..     607     749 .. 0.94

  Alignments for each domain:
  == domain 1  score: 77.0 bits;  conditional E-value: 2.2e-24
                 EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSS.........STTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHH CS
         AAA   1 vllyGppGtGKTllakavakelgvefleisgsellsk.........yvgesekkirelfkeakekakpsilfiDEidalaksrsgseseeeervvnqLl 90 
                 ++l+GppG+GKT++ k++a+ l+++++++s+  l++          yvg+ + +i + +k++++++    ++iDE+d++++         + + +++Ll
  EEA21138.1 607 LCLVGPPGVGKTSIGKSIARALNRQYYRFSVGGLTDVaeikghrrtYVGALPGRIIQALKKCQTEN--PLILIDEVDKIGRGH-------QGDPASALL 696
                 58*********************99999999999966889999999*****************998..9**********8888.......999****** PP

                 HHHHHTTTS............SSTEEEEEEESSGGGSTHHHHSTTSSE CS
         AAA  91 teldgvkkk............eskvivigatnrpdkldpallrgRfdr 126
                 + ld ++++             skv++++++n  d+++++ll +R++ 
  EEA21138.1 697 ELLDPEQNSsfldhymdvpvdLSKVLFVCTANVTDTIPRPLL-DRMEL 743
                 *********************999******************.9*986 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.1   0.0   2.5e-10   1.9e-07       2     124 ..     607     731 ..     606     741 .. 0.71

  Alignments for each domain:
  == domain 1  score: 31.1 bits;  conditional E-value: 2.5e-10
                 EEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--..........--------.G-SEEEEESGGG--H....HHHHHHHHHHHSSEE CS
       AAA_5   2 vlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreikngtts.lvdsplvraar.egeilvlDEveraes....evlnsLlslleerrl 94 
                 ++LvGppG+gK+++ +++a+alnr++        t  +++kg+r++  g    +  ++l+ +++ e  ++++DEv+++ +    + +++Ll ll+ ++ 
  EEA21138.1 607 LCLVGPPGVGKTSIGKSIARALNRQYYRFSVGGLTDVAEIKGHRRTYVGALPgRIIQALK-KCQtENPLILIDEVDKIGRghqgDPASALLELLDPEQN 704
                 79*******************************************864444303334444.4446999********98651222556788888887766 PP

                 E..-SSSEEE---......-EEEEEESS-- CS
       AAA_5  95 lleeggelvkaknddllerfrviatanpld 124
                 +   ++++++++ d  l+++ ++ tan  d
  EEA21138.1 705 S-SFLDHYMDVPVD--LSKVLFVCTANVTD 731
                 5.445555555543..34477777777766 PP

>> AAA_PrkA  PrkA AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.1       4.5   3.5e+03      88     115 ..     489     516 ..     485     526 .. 0.77
   2 !   24.8   0.0   1.2e-08   9.1e-06      55     114 ..     571     630 ..     559     642 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 4.5
    AAA_PrkA  88 kqilyllGPvggGksslverlkklleaa 115
                 k i   lG  + Gk  lve++k+  e+ 
  EEA21138.1 489 KGIKRELGIESDGKDKLVEKFKEKAEKL 516
                 5566667888999999999999988876 PP

  == domain 2  score: 24.8 bits;  conditional E-value: 1.2e-08
    AAA_PrkA  55 kypafeedffGleetiekiveyfraaaqrleerkqilyllGPvggGksslverlkkllea 114
                   ++++ed +Gl+++ ++i+e++     r+ ++ +il l+GP g Gk+s+ +++ ++l+ 
  EEA21138.1 571 AMSVLDEDHYGLKDVKDRILEFIAVGKLRGSVEGKILCLVGPPGVGKTSIGKSIARALNR 630
                 467899************************************************999976 PP

>> AAA_2  AAA domain (Cdc48 subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.6   0.0     3e-08   2.3e-05       7     132 ..     608     732 ..     603     762 .. 0.76

  Alignments for each domain:
  == domain 1  score: 24.6 bits;  conditional E-value: 3e-08
                 EEE--TTSSHHHHHHHHHHHTT-....-EEEEEGGG---.----THHHHHHHHH..TTT-HHHHTTSEEEEETGGG-------------HHHHHHHHHH CS
       AAA_2   7 lllgptgvGktelakalaellfvkkekkliradaselle.eeevehlvsrliga..ppgyvgaeegGivllDEidKihpkessgadvSregVqrdLLqi 102
                  l+gp gvGkt + k++a+ l+ ++  ++ +   ++++e +   +++v  l g   +   + + e+  +l+DE+dKi +         + +   +LL +
  EEA21138.1 608 CLVGPPGVGKTSIGKSIARALN-RQYYRFSVGGLTDVAEiKGHRRTYVGALPGRiiQALKKCQTENPLILIDEVDKIGR-------GHQGDPASALLEL 698
                 478*******************.78888888888888884444445555554431133333444555************.......223467889**** PP

                 HH--EE-...----.--EE-TT-EEEEEE--TTH CS
       AAA_2 103 leggtlt...dkqg.rkvdtknilfImtgafgss 132
                 l+  + +   d++   +vd +++lf++t ++  +
  EEA21138.1 699 LDPEQNSsflDHYMdVPVDLSKVLFVCTANVTDT 732
                 *95444444466666***************9765 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.3   0.1   1.6e-07   0.00012       5     110 ..     604     697 ..     601     727 .. 0.79

  Alignments for each domain:
  == domain 1  score: 22.3 bits;  conditional E-value: 1.6e-07
      AAA_22   5 agilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelkaerlsseellealeqalrarav.ielliiDEaqh 102
                  +il+++G++G+GKT   + +++ l         +++++++ + ++t       +++++ g+++ +      +l  ++ qal+++++  +l++iDE+++
  EEA21138.1 604 GKILCLVGPPGVGKTSIGKSIARAL---------NRQYYRFSVGGLT-------DVAEIKGHRRTY----VGALPGRIIQALKKCQTeNPLILIDEVDK 682
                 689**********************.........9998888888888.......556666654444....667889*********************** PP

      AAA_22 103 lr...s....eeale 110
                 +    +     ++le
  EEA21138.1 683 IGrghQgdpaSALLE 697
                 965542444333333 PP

>> ChlI  Subunit ChlI of Mg-chelatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.7   0.0   4.3e-08   3.3e-05      40     121 .]     970    1051 ..     926    1051 .. 0.76

  Alignments for each domain:
  == domain 1  score: 23.7 bits;  conditional E-value: 4.3e-08
        ChlI   40 fpakkitvnLaPadlkkeGsafDLpiAigilaaleqieaeeetlflGeLsldGslrpvkgvlpialaakkegikkvivpken 121 
                  f++ ++ +      ++k+G++  +++A ++l+ + + + + ++ + GeL  +G++ ++ g+ + ++aa+++g kk++ p++n
  EEA21138.1  970 FEKARVHLHCPEGAVQKDGPSAGITMATSLLSLALNHPLDPTIAMTGELTVTGKVLRIGGLREKTVAARRAGAKKILFPADN 1051
                  4444555555556799***************************************************************998 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.1       8.7   6.8e+03      80     107 ..     457     493 ..     427     539 .. 0.55
   2 !   20.3   0.1   7.3e-07   0.00057      24      76 ..     604     657 ..     586     699 .. 0.73

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 8.7
      AAA_16  80 ellrqlldeaesaeleawrekleeala.........a 107
                 el+++ l+ + s+++ea  +k ++++           
  EEA21138.1 457 ELINAQLQSKISKDVEAKIQKRQREYWlmeqmkgikR 493
                 5555555555555555555555555543333332221 PP

  == domain 2  score: 20.3 bits;  conditional E-value: 7.3e-07
      AAA_16  24 pelvllsGesGvGKsslvrellralekdggiflrgkcdql.esaipysalaqal 76 
                 + ++ l+G++GvGK+s+ ++++ral++++  f  g  ++  e + ++ +++ al
  EEA21138.1 604 GKILCLVGPPGVGKTSIGKSIARALNRQYYRFSVGGLTDVaEIKGHRRTYVGAL 657
                 3899************************88886666666522222222344444 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.0   6.5e-07   0.00051       7      62 ..     577     633 ..     573     649 .. 0.87

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 6.5e-07
      RuvB_N   7 eeyigqekvkeklkifieaakkreealdhvl.lyGpPGlGkttlakiiakelgvklk 62 
                 e++ g ++vk+++  fi+  k r++    +l l+GpPG+Gkt++ k ia+ l+ +  
  EEA21138.1 577 EDHYGLKDVKDRILEFIAVGKLRGSVEGKILcLVGPPGVGKTSIGKSIARALNRQYY 633
                 578899********************99998689****************9998765 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.1       6.5   5.1e+03      38      69 ..     484     514 ..     441     534 .. 0.56
   2 !   15.1   0.0   3.3e-05     0.026       2      25 ..     608     637 ..     607     683 .. 0.82
   3 ?   -1.1   0.0       3.4   2.6e+03      77     103 ..     959     981 ..     922     985 .. 0.68

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 6.5
      AAA_18  38 llevdpealdeskrldedkldklldaleenss 69 
                 l e+ +  +++++ ++ d  dkl+++++e ++
  EEA21138.1 484 LMEQMKG-IKRELGIESDGKDKLVEKFKEKAE 514
                 2222222.444555555555555555555544 PP

  == domain 2  score: 15.1 bits;  conditional E-value: 3.3e-05
      AAA_18   2 lltGtpGvGKttlakeLskrlgf......g 25 
                 +l G+pGvGKt+++k +++ l+       +
  EEA21138.1 608 CLVGPPGVGKTSIGKSIARALNRqyyrfsV 637
                 799***************998555555443 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 3.4
      AAA_18  77 lvidghlaeleseaakdikkvvLtasp 103
                 +  ++++++ ++e+a+    v+L++++
  EEA21138.1 959 VMAQDFPENRFFEKAR----VHLHCPE 981
                 3334444444444444....*****97 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   1.6e-05     0.012       2      77 ..     604     689 ..     603     730 .. 0.67

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 1.6e-05
      AAA_14   2 rkilvitGaRrvGKTtllkqlikellvkkesilyinldderd....kkladpe........kllelileklkeekktylflDEiqev.....p 77 
                 +kil+++G+  vGKT + k +++ l    +++  +++   +d    k ++  +        ++++++++  +  ++ ++++DE+ ++      
  EEA21138.1 604 GKILCLVGPPGVGKTSIGKSIARALN---RQYYRFSVGGLTDvaeiKGHR--RtyvgalpgRIIQALKKC-Q-TENPLILIDEVDKIgrghqG 689
                 699*******************9988...888888877766643332222..124563333444444443.3.5899*******998555551 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   6.2e-05     0.049      19      97 ..     605     680 ..     595     698 .. 0.67

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 6.2e-05
      AAA_30  19 rvavltGpAGtGKttalkalreaweaag..grviglAptgkaAkvLaeelgi.eastiakllkrlkgrarlepgtllivDEa 97 
                 ++ +l+Gp+G GKt + k++++a++++   ++v gl+  ++     ++ +g+ +++ i+ l k ++      ++ l+++DE+
  EEA21138.1 605 KILCLVGPPGVGKTSIGKSIARALNRQYyrFSVGGLTDVAEIKGHRRTYVGAlPGRIIQALKKCQT------ENPLILIDEV 680
                 5889****************9999999612555555555554444444555324444444442222......2356666665 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   7.1e-05     0.056      48     117 ..     605     680 ..     570     705 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 7.1e-05
   IstB_IS21  48 enivllGpsGvGKshlaialgveavraglsvlfvrvedLveelkrarrd......gklaralkrllkv.dllilDdl 117
                 + ++l+Gp+GvGK+ +  +++++  r+ ++ +   ++d+ +e+k +rr       g++ +alk+++    l+++D++
  EEA21138.1 605 KILCLVGPPGVGKTSIGKSIARALNRQYYRFSVGGLTDV-AEIKGHRRTyvgalpGRIIQALKKCQTEnPLILIDEV 680
                 5689******************99999988877777774.3444444432222225555566555444245566665 PP

>> DUF4276  Domain of unknown function (DUF4276)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.2   8.9e-05     0.069      77     144 ..     462     539 ..     421     558 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 8.9e-05
     DUF4276  77 didskgderfipyiqlhefEawlladpealk........ekseslsklkkirkefsnPenindgpktapskr..leea 144
                 + +sk ++++ + iq +  E wl+ +++ +k         k++ ++k+k+ +++++ Pe+++ + ++++ k   le a
  EEA21138.1 462 QLQSKISKDVEAKIQKRQREYWLMEQMKGIKrelgiesdGKDKLVEKFKEKAEKLAMPEAVKKVFDEELNKLahLEPA 539
                 33444799999***************************9999********************9999988875445555 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       5.3   4.1e+03     112     150 ..     221     262 ..     218     269 .. 0.69
   2 ?   10.2   0.0   0.00068      0.53       3      33 ..     608     640 ..     606     655 .. 0.75
   3 ?    0.1   0.0      0.82   6.4e+02      84     106 ..     660     682 ..     647     689 .. 0.83

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 5.3
                 HHHHHHHHHHHTTTSEEEEE--SS-...-SHHHHHHHT-TT- CS
    NTPase_1 112 kkfkeaveevLksekpvlavihrrk...dlalveeirerkdv 150
                 ++++ a++e++k+++p ++ +  ++   d +++e++ +  dv
  EEA21138.1 221 PNVAAAIQEMMKRGQPYVGAFLFKNddaDGDIIENMDDVYDV 262
                 5788999*****999999987666544555566665555555 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.00068
                 EEE--TTSSHHHHHHHHHHHH.....GGGEEEE CS
    NTPase_1   3 fiTGppGvGKtTlvkkvlellkss..gvkvgGf 33 
                 ++ GppGvGKt + k ++++l+++   ++vgG+
  EEA21138.1 608 CLVGPPGVGKTSIGKSIARALNRQyyRFSVGGL 640
                 688******************988334456665 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.82
                 HHHHHHHHHHHHH-EEEE---ST CS
    NTPase_1  84 lalealrkalseadviviDEiGk 106
                  +++al+k ++e+ +i+iDE+ k
  EEA21138.1 660 RIIQALKKCQTENPLILIDEVDK 682
                 57889999999999******955 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   0.00026       0.2       1      27 [.     607     639 ..     607     698 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00026
  RNA_helicase   1 iwlyGpsgeGKStlakeLakallkkl......k 27 
                   ++l+Gp+g+GK+++ k++a+al +++      +
    EEA21138.1 607 LCLVGPPGVGKTSIGKSIARALNRQYyrfsvgG 639
                   589*******************98875555550 PP

>> CHASE8  Periplasmic sensor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       6.6   5.2e+03      51      73 ..     319     343 ..     317     364 .. 0.71
   2 ?   11.4   0.1   0.00038       0.3      21      83 ..     423     486 ..     420     502 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 6.6
      CHASE8  51 ydaegkllaeyaresseak..eele 73 
                 y+++g + a++++++ ea+  e ++
  EEA21138.1 319 YEKKGDVVASFEEGAVEAPpkEVYH 343
                 7899*******99998887533333 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00038
      CHASE8  21 eAAlvFeDaaaAreiLaaLkaepeiaaaavydaegkllaeyaresseak.eeleallaslllpe 83 
                  AA++ +D+++ +e+L+a++ e+ + +a v+ +++ + a+ +++ s++   +++++++++ l+e
  EEA21138.1 423 AAAVASGDSQEVQEVLEAMNIEERLPKALVVLKKELINAQLQSKISKDVeAKIQKRQREYWLME 486
                 79*****************************999999998888876665466666666555554 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00028      0.22      90     123 ..     595     628 ..     574     637 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00028
                  HHHHHHHCTTSEEEEECSTTSSHHHHHHHHCTT- CS
  RsgA_GTPase  90 leelkellkdktsvlvGqSGvGKStLinallpel 123
                  + +l+  +++k+ +lvG+ GvGK+++ ++++  l
   EEA21138.1 595 VGKLRGSVEGKILCLVGPPGVGKTSIGKSIARAL 628
                  66899999*****************988887655 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.2       2.9   2.3e+03      68      74 ..     461     467 ..     330     535 .. 0.64
   2 ?   11.1   0.1   0.00053      0.41      10      36 ..     603     629 ..     600     654 .. 0.91

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 2.9
                 --S-TTS CS
                 xxxxxxx RF
    ABC_tran  68 pqlfpel 74 
                 +ql++++
  EEA21138.1 461 AQLQSKI 467
                 2222222 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00053
                 TTSEEEEEESTTSSHHHHHHHHTTSS- CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  10 egekvaivGenGaGKStLlkllagllk 36 
                 eg+++ +vG+ G GK+++ k +a+ l+
  EEA21138.1 603 EGKILCLVGPPGVGKTSIGKSIARALN 629
                 799*******************99876 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       5.6   4.4e+03      45      89 ..     429     474 ..     425     483 .. 0.54
   2 ?   10.4   0.0   0.00043      0.33      34      63 ..     605     634 ..     601     642 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 5.6
       AAA_7  45 GKtviikdllkkld.kekylsltinfsaqtsanqlqdiiesklekr 89 
                 G +  ++++l++++ +e++  + + +++    +qlq+ i + +e +
  EEA21138.1 429 GDSQEVQEVLEAMNiEERLPKALVVLKKELINAQLQSKISKDVEAK 474
                 5566666666666634444444455566666666666665554433 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00043
       AAA_7  34 kpvllvGptGtGKtviikdllkkldkekyl 63 
                 k ++lvGp G+GKt+i k++ ++l+++ y 
  EEA21138.1 605 KILCLVGPPGVGKTSIGKSIARALNRQYYR 634
                 66789*******************977665 PP

>> Apt1  Golgi-body localisation protein domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   5.0   0.00031      0.24     312     412 ..      66     237 ..      44     240 .. 0.49

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00031
        Apt1 312 ss..seeddesdeesessssssssssssassssssssrssslelrlkptsstssssssessssssskkrsseesslessaserv.............ks 395
                  +  ++  ++ +++  ++++ ++++ +s+++s + +++++s + +++p+ +  +s+++++++ +++kk +s+  +++s+ s++              + 
  EEA21138.1  66 APpsEDAPENAENNDGAEGKDTTKQVDSRRKSGDATDKQGSTQTTDTPSRRRDKSNAEKEEQAEVTKKGESQ--QAKSRDSKADssspspipvsgggG- 161
                 223211111111111222222233333333333333333333333333322222222222222222221111..111111111111122334544441. PP

        Apt1 396 sr............................................................asddleemksRasky 412
                  +                                                                ++em++R + y
  EEA21138.1 162 -SeskpsggngnddggrrgrkgekslqkpfipdvypqvmsipiarrplfpgfykaitvkdpnVAAAIQEMMKRGQPY 237
                 .0445566667777777888888899999999999999999999999999999999999999899999999997766 PP

>> Presenilin  Presenilin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   7.9    0.0067       5.2     209     310 ..      43     145 ..      38     179 .. 0.44

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0067
  Presenilin 209 eifpaLiYsatvvvlaaeekkaevaeseeeeeaekkkeeasesskeeesee.esseksaqsseseeeseeesseaessaeesseekeseessesseeee 306
                 +ifp    +++++++++++ k+++ +se++ e+ ++++ a+ ++++++ ++ ++s + + ++ s++++++ s++ ++s++e++e++e +++ es+++++
  EEA21138.1  43 PIFPTPTIASRAFTSSRTSYKEKAPPSEDAPENAENNDGAEGKDTTKQVDSrRKSGDATDKQGSTQTTDTPSRRRDKSNAEKEEQAEVTKKGESQQAKS 141
                 556655555666655444443333333332222222222222222222222022222222222333333333333333333333333333333333322 PP

  Presenilin 307 eeee 310
                 ++++
  EEA21138.1 142 RDSK 145
                 2222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1072 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1564  (0.087233); expected 358.6 (0.02)
Passed bias filter:                      789  (0.0440069); expected 358.6 (0.02)
Passed Vit filter:                       152  (0.00847788); expected 17.9 (0.001)
Passed Fwd filter:                        26  (0.00145016); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              23  [number of targets reported over threshold]
# CPU time: 0.96u 0.34s 00:00:01.30 Elapsed: 00:00:00.47
# Mc/sec: 6805.65
//
Query:       EEA21139.1  [L=1012]
Description: Protein kinase domain-containing protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.5e-10   39.7   0.0      9e-09   35.1   0.0    2.5  1  Pkinase      Protein kinase domain
    3.4e-09   36.4   0.0    5.6e-08   32.4   0.0    2.4  1  Pkinase_Tyr  Protein tyrosine kinase


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.1   0.0     1e-12     9e-09      23     259 ..     348     560 ..     339     563 .. 0.75

  Alignments for each domain:
  == domain 1  score: 35.1 bits;  conditional E-value: 1e-12
                 TTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHS.CTTB--EEEEEEE...SSEEEEEEE--TTEBHHHHHH.HHSS--HHHHHHHHHHHHHHHHHHHH CS
     Pkinase  23 tgkivAvKkikkekakkkkekkvlrEikilkklk.hpnivrlyevfee...kdelylvleyveggeladlle.rkgslseeeakkiakqilegleylHs 116
                 +gk +  K+i   ++     +++l Ei+ l+ l+ ++ ++++ +++ +   ++   l+  y+e+g l d+l   +g+l+ ++ +++a+qi++gl  +H+
  EEA21139.1 348 DGKAYIKKEIPGPDTV----DEFLYEINALHALHgSQSVIQFEGIIVDdhlERVKGLLISYAEQGALVDVLYdFRGQLPLARRERWARQIVQGLCEIHE 442
                 5555655666555544....4689**********9**********99865444445*************99977899********************** PP

                 TTEE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCSBCTTTSCGGGS-HHHH.......TTSCB.SHHHHHHHHHHHHHHHHHSS-STTTSSHHHHHH CS
     Pkinase 117 kgiiHrDlKpeNiLidekgelKitDFGlakelessskltsfvgtseYlAPEvl.......keney.skkvDvWslGvilyelltgkppfsgekgkekve 207
                 +g +  D   +Ni id +++ Ki+D        ++       +   + +PE+        + ++y + k+D++ lG++l+ l +++   +         
  EEA21139.1 443 AGYVQGDFTLSNIVIDGNDNAKIIDIN------RR------GCPVGWEPPEIAakiesnqRISMYiGVKSDLFQLGMTLWALAMQEDEPE--------- 520
                 *************************53......32......2445566666655554433226666999999999999999866654444......... PP

                 HHHHTHHHHHHHCTSHH...HHHTTS-HHHHHHHHHHT-SSGCCSTTHHHHH CS
     Pkinase 208 keldqlekilkilgetkeklpeaseiseeakdllkkllkkdpkkRltaeell 259
                    +q         +  + +p + +i++  ++++  +l+  p++Rl+a+ell
  EEA21139.1 521 ---RQ---------PRPLFIPIDMKIPDYYRRVIAHCLSDRPRDRLSAKELL 560
                 ...22.........22234567777888888888888888888888888887 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.4   0.0   6.3e-12   5.6e-08      44     206 ..     362     520 ..     350     563 .. 0.83

  Alignments for each domain:
  == domain 1  score: 32.4 bits;  conditional E-value: 6.3e-12
                  HHHHHHHHHHHHHTS.-BTTB--EEEEEE...SSSSEEEEEE--TTEBHHHHHHHTCTTTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEE CS
  Pkinase_Tyr  44 ekeelleeakimkkl.khpnivkllgvct...keepllivteyvkgGdLlkfLrkkekekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLls 137
                  + +e+l e++ +++l   + ++++ g+++    e+   +++ y+++G L + L +  + +l l +  ++a q+ +G+  +++  +v  d +  N++++
   EEA21139.1 362 TVDEFLYEINALHALhGSQSVIQFEGIIVddhLERVKGLLISYAEQGALVDVLYDF-RGQLPLARRERWARQIVQGLCEIHEAGYVQGDFTLSNIVID 458
                  5689***********8899**********653333378999**************9.***************************************** PP

                  ETTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSE........EEHHHHHHHHHHHHHHHHTTSSGTT CS
  Pkinase_Tyr 138 enkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekk........ftsksDvWsfGvllwEiftlgespy 206
                   n+ +ki D                +++ +pv W +pE+  + +        + +ksD +  G++lw ++ + ++p 
   EEA21139.1 459 GNDNAKIIDI---------------NRRGCPVGWEPPEIAAKIEsnqrismyIGVKSDLFQLGMTLWALAMQEDEPE 520
                  *******984...............3345899999999988777777888888899**********99998777764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1012 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       437  (0.0243739); expected 358.6 (0.02)
Passed bias filter:                      301  (0.0167884); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.72u 0.27s 00:00:00.99 Elapsed: 00:00:00.47
# Mc/sec: 6513.64
//
Query:       EEA21140.1  [L=291]
Description: isoflavone reductase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.1e-12   47.1   0.0    3.1e-12   46.5   0.0    1.2  1  NmrA             NmrA-like family
    4.7e-11   42.9   0.0    6.1e-11   42.5   0.0    1.3  1  NAD_binding_10   NAD(P)H-binding
    9.7e-05   22.6   0.0    0.00016   21.9   0.0    1.4  1  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma
  ------ inclusion threshold ------
      0.082   13.5   0.0       0.14   12.7   0.0    1.4  1  Biotin_carb_N    Biotin carboxylase, N-terminal domain
       0.18   11.2   0.0       0.26   10.7   0.0    1.3  1  Epimerase        NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.5   0.0   8.8e-16   3.1e-12       1     198 [.      10     198 ..      10     207 .. 0.84

  Alignments for each domain:
  == domain 1  score: 46.5 bits;  conditional E-value: 8.8e-16
                 EEESSTTSHHHHHHHHHHHH.HT-EEEEEES-S-SHHHHHHHHSTTEEEES-TT-HHHHHHHHTT-SEEEE---GGS-HHHHHHHHHHHHHHHS-SEEE CS
        NmrA   1 IlviGaTGrqGksvvrallk.aghkvralvRdtkselakslkeaGvelvkgdlddkeslvealkgvdvvfsvtgfyskeiedgkklvdAakeaGvkhfi 98 
                 ++++Ga G+ Gk++++all+  +h+v  l+R  ++ ++     +Gv     d +  e +veal+g ++  +++g     +    kl++Aa +aGv+ ++
  EEA21140.1  10 VAIVGAGGNSGKFMTEALLRtGKHTVTTLTRADSRSALP----EGVIPKVVDYEKPETIVEALNGQEALVITLG--AYALSNEFKLIEAAEKAGVQWIL 102
                 79******************77899999**977665553....466655889**********************..8899999**************** PP

                 EEE---GG.GT.SSS---TTTHHHHHHHHHHHHC.TS-EEEEEE-EEGGG-BSSS-SS-BEEE-TTS.-EEEEESS-TTS-EE-HHHHHHHHHHHHHHH CS
        NmrA  99 ySslgddndrsnaeepavphfdsKaeieeyvral.gipytfvyagffmenflsllaqlkvgdtappedkvtllgpgnpkavlldaeeDiGafvikilkd 196
                 +++  +     n ++ ++ ++++K + +e++ +l    y  v +gf++e  l+++    +g   + + +vt+  +g++ka +  + + +G++v+++l+ 
  EEA21140.1 103 PNEWSSYP-GANEHIKDMFFYQMKSSTREALGELrNSSYIGVSTGFWYEWSLPMPLA--FGFDITHR-SVTFFDEGEAKASVS-TWAQVGRAVAALLSL 196
                 87777777.4446667899*************99334445589**********8888..55555555.799******999999.**********99987 PP

                 HH CS
        NmrA 197 pr 198
                 p 
  EEA21140.1 197 PV 198
                 65 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.5   0.0   1.7e-14   6.1e-11       1     132 [.      14     136 ..      14     195 .. 0.82

  Alignments for each domain:
  == domain 1  score: 42.5 bits;  conditional E-value: 1.7e-14
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHHCTTTCEEEE--TT-CCHHHHHHTT-SEEEES---TCCHHHHHHHHHHHHHHCT--EEE. CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpeklaeleaeeglevvegdvtdvedlaealkgadaVvsalggggkdeegaknivdaakeagvkRfv. 94 
                     GA G+ G+  ++ ll+ g+h+vt l+R  ++ a l+  eg+   ++d +++e++ eal+g++a v++lg+ +       ++++aa++agv+ ++ 
      EEA21140.1  14 GAGGNSGKFMTEALLRTGKHTVTTLTRADSRSA-LP--EGVIPKVVDYEKPETIVEALNGQEALVITLGAYAL--SNEFKLIEAAEKAGVQWILp 103
                     9******************************98.86..79999999***********************9887..4578***********98872 PP

                     ..EEEETTTTSGCGCHHHHHHHHCCHHHHHHHHHHHHHHH CS
  NAD_binding_10  95 ..lvsaigvgdevpgefgewnkellkaylaakraaeellr 132
                       + s+ g+++++++ f       + ++    r+a  +lr
      EEA21140.1 104 neWSSYPGANEHIKDMF-------FYQMKSSTREALGELR 136
                     22344444444433333.......3333344444444444 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.9   0.0   4.6e-08   0.00016       1      97 [.      10     101 ..      10     130 .. 0.86

  Alignments for each domain:
  == domain 1  score: 21.9 bits;  conditional E-value: 4.6e-08
                      EEEE--.SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHHHTTSSEEEE-SSGG..GHHHHHHHHHH CS
  Sacchrp_dh_NADP   1 vliiGa.GsvGqavaellarhfdvdaeitvadrskeklealaakalgvrfeaialdaenyeavLaallkegdlvvnlsppi..ssldvlkaCie 91 
                      v i+Ga G+ G++++e l+r++++  ++t  +r +++   +    l + ++++ +d e++e +++al  +  lv+ l  +      ++++a+ +
       EEA21140.1  10 VAIVGAgGNSGKFMTEALLRTGKH--TVTTLTRADSR--SA----LPEGVIPKVVDYEKPETIVEALNGQEALVITLGAYAlsNEFKLIEAAEK 95 
                      679*******************99..89999999999..33....5789*************888877777999999999964444999**999 PP

                      HT-EEE CS
  Sacchrp_dh_NADP  92 tgvhyv 97 
                      +gv  +
       EEA21140.1  96 AGVQWI 101
                      999765 PP

>> Biotin_carb_N  Biotin carboxylase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   3.9e-05      0.14      37     106 ..      33     104 ..       7     107 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 3.9e-05
                    TTSHHHHHSSEEEEEESST..TCCGGG-HHHHHHHHHHTT-SEEE--SSTTTT-HHHHHHHHHTT-EESSS- CS
  Biotin_carb_N  37 anslhvreadeavelgpas..asesYlniekivkaakesgadavhpGyGflsEnaefaeaveeagivfiGPs 106
                    ++ + ++ ad+   l+++   +   Y + e iv+a++ ++a  +  G   ls++ ++ ea e+ag+ +i P+
     EEA21140.1  33 HTVTTLTRADSRSALPEGVipKVVDYEKPETIVEALNGQEALVITLGAYALSNEFKLIEAAEKAGVQWILPN 104
                    5566677788888887554227789********************************************886 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   7.3e-05      0.26       2      72 ..      11      79 ..      10     101 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 7.3e-05
                EEETTTSHHHHHHHHHHHHCT.SEEEEEES-STTTTCHHCHHCEEEE--TT-HHHHHHHHHHHT-SEEEE-- CS
   Epimerase  2 lVtGatGfiGsalvkallekg.yevigldrlssasntarledlelveldltdrsalerlfkeeqpdavihlA 72
                 ++Ga G  G+ +++all+ g ++v++l+r   +s++a+ e +    +d+ +++ + ++++  q   vi l+
  EEA21140.1 11 AIVGAGGNSGKFMTEALLRTGkHTVTTLTRA--DSRSALPEGVIPKVVDYEKPETIVEALNG-QEALVITLG 79
                699******************999*******..55555666666667777777777777774.445555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (291 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       422  (0.0235373); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1900.83
//
Query:       EEA21141.1  [L=565]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-13   50.3   0.6    3.9e-13   49.4   0.6    1.4  1  CorA      CorA-like Mg2+ transporter protein
  ------ inclusion threshold ------
      0.045   12.5   0.1      0.061   12.1   0.1    1.2  1  DUF2207   Predicted membrane protein (DUF2207)


Domain annotation for each model (and alignments):
>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.4   0.6   4.4e-17   3.9e-13     108     289 ..     362     554 ..     343     558 .. 0.67

  Alignments for each domain:
  == domain 1  score: 49.4 bits;  conditional E-value: 4.4e-17
        CorA 108 pgellyrlldeivdrlfellekleeeldeledel.........edstkkeilrelaqlrrrlvklrralapnrevlk..rlla.kaddkllddedkeyl 194
                 p ++  ++l  i+ + +++ e + ++l ++e el         e++  +  l+ l   rr++ ++r+++++  + +   ++l+ ++ +++  ++ +e +
  EEA21141.1 362 PNTFAVAILSIIAIEWLTVKEYVTTRLTQIEWELevpdfrghgEKYGLDASLKWLHPFRRNVPRYRKWVTNILNGILgdKNLSpTDSKDQSLRDLREDF 460
                 566666666666666666667777777777777755555555555555555555555666666666666666555544444444455555555555566 PP

        CorA 195 rdlldelerllemlealrerleslqdtyssllserlNrvmkvLTvltaiflPlTlitGiyGmNfkglPelewsygypfvlllglmallailllfw 289
                   +l +le l+ +++ l ++++ + ++  +  s ++N+ + +LT l+++f+Pl+++++++ mN + +  l + ++ +f++ + l++l+  ++ +w
  EEA21141.1 461 LIILKDLETLQAQVQDLVRVVTAIISIEEAKRSAEQNKSLARLTYLAVVFVPLSFVSSFFSMNSD-IASLRTTFWIFFAVAVPLTLLSLSVTRWW 554
                 66666666666666666666666666666666677******************************.99999999777776666666666665555 PP

>> DUF2207  Predicted membrane protein (DUF2207)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.1   6.8e-06     0.061     315     442 ..     423     564 ..     358     565 .] 0.73

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 6.8e-06
     DUF2207 315 ldpyEkalldlLfdkseeg.ks.lkeikkyakkskk.......kakkfkkalkkwksavkk...kergyfdkkgkkklkklsalglgliilglililla 401
                 +++y k + ++L++  +++  s +++  + +++ ++       + ++++++++++ + v++    e+   +++++k l++l +l+++++ l+++ ++++
  EEA21141.1 423 VPRYRKWVTNILNGILGDKnLSpTDSKDQSLRDLREdfliilkDLETLQAQVQDLVRVVTAiisIEEAKRSAEQNKSLARLTYLAVVFVPLSFVSSFFS 521
                 4677788888888777777666765566666665555556666777777777777777777**855555555567888999999999999999999887 PP

     DUF2207 402 llllvll..lvfllilllillliaiivlllfsrllgrrteeGa 442
                 + + ++    +f+ +++++++l ++ + +   + + r+ + G+
  EEA21141.1 522 MNSDIASlrTTFWIFFAVAVPLTLLSLSVTRWWAITRWLRRGR 564
                 6554443888999999999999988888888888888888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (565 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       648  (0.0361426); expected 358.6 (0.02)
Passed bias filter:                      467  (0.0260472); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.46
# Mc/sec: 3704.15
//
Query:       EEA21142.1  [L=963]
Description: NRPS-like enzyme, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.4e-53  181.3   0.0    3.2e-53  180.8   0.0    1.1  1  AMP-binding    AMP-binding enzyme
    3.1e-29  102.7   0.0    1.5e-28  100.5   0.0    2.1  1  Thioesterase   Thioesterase domain
    7.8e-12   45.4   1.3    1.8e-11   44.2   1.3    1.7  1  PP-binding     Phosphopantetheine attachment site
  ------ inclusion threshold ------
      0.017   15.7   0.0      0.041   14.5   0.0    1.7  1  Abhydrolase_6  Alpha/beta hydrolase family


Domain annotation for each model (and alignments):
>> AMP-binding  AMP-binding enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  180.8   0.0   7.2e-57   3.2e-53      20     422 ..      71     471 ..      50     472 .. 0.85

  Alignments for each domain:
  == domain 1  score: 180.8 bits;  conditional E-value: 7.2e-57
                  TEEEEHHHHHHHHHHHHHHHH.HTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEET.....TS-HHHHHHHHHHHTESEEEETCTCCCHHHHH CS
  AMP-binding  20 gqtlTYreldervnrlAagLr.slGvkkgdrVaillpnspewvvallailkaGavvvplnp.....tltaeelayiledseakvliatvdsellekll 111
                   + ++Y +l e+++  A+ L    ++++ ++ ++  +  ++ + ++ a+  aG+ ++   p       ++++l+++ +  +  v++  + ++l+++ +
   EEA21142.1  71 PTFVSYFDLLEEATHKARLLStIEDLTPSTVLLLHFDSQHDTIEWFWAATLAGILPAISTPlvndaVQRNKHLKHLQTLLQQPVIL--TAKHLIPEFD 166
                  56689****************988*****************************988887775555566779999999999999999..7777777776 PP

                  HHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHHHHC.SCCTTT-EEEES CS
  AMP-binding 112 eaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkletr.fklkeddvvlsi 208
                   +++        + l+a+ell  e+ +++++s +      +  + ++ dla+++ TSG+TG+ K+V l+h++++ +v+s k     + + ++d +l +
   EEA21142.1 167 GIEG--------LRLHAAELL--ECNHSTSPSVSI-----TGIKKQKGDLAVLMLTSGSTGNAKAVALRHGQIIKAVQS-K--SSfHAIAPGDPFLNW 246
                  6665........445544444..334444444433.....3346799*****************************999.3..33234678******* PP

                  S-TTSCHHHHHHHHHHHHTT-EEEE-TTCGC.CHHHHHHHHHHHHT-SEEEEEHHHHHHHHH.CCCHHCHHHHCCGTT-SEEEEESS-EBHHHHHHHH CS
  AMP-binding 209 lplahifglilelllallsGatvvllpkdaa.ldpklllelieklkvtviagvPrvlealle.sgalkaakkakdlsslrlvllggeplspellrffr 304
                  + + h+++l+   l a++ G+  v +p  +  ++p +++el++ +k+ ++++++ +l ++l+  +a +  +   dls+l+ +++g+e+   ++ +++ 
   EEA21142.1 247 VGMDHVASLTEIHLHAMSLGSDQVHVPAIELlRNPLRFIELLDMHKIVYTFAPNFFLAKILNsLKANQ--TMTADLSRLKAFIAGAEASVVTTCDALT 342
                  *********999999****************777****************************444333..4455********************9999 PP

                  HHHTC......EEEEEEEEGGGSSECEE........CHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBE.ETTSEEEEEEEETTS-SEBTT-HHHHHH CS
  AMP-binding 305 alfge......evlegYGlTEttgvvtv........lpleedkkklgsvGkplpgvevkivDeetgepv.pdgeeGellvrgpgvmkgYlkkpeatae 387
                  + f++       +  g+G+TE++g +++        l            G+ +pgve+++vD +++ +  pdge+Ge  v+gp v+  Y+++ eata 
   EEA21142.1 343 REFRRfgvqaeVIRPGFGMTEMCGGTIYslacpsydL---AAGLEFANLGTCIPGVEMRVVDLNNKTEKaPDGEVGEFQVSGPVVFNHYFNNAEATAN 437
                  99999999998899************77778786432...3333466799***********9886655548*************************** PP

                  HEEETCCEEEEEEEEEEETTSEEEEEEECCCEEEE CS
  AMP-binding 388 afdsegrwlrTGDlgrldedGyleivgRkkdlikl 422
                  +f   ++w+ TGDl+r+de G+l + gR+kd+i++
   EEA21142.1 438 SFS-ADGWFITGDLARIDEAGNLILAGRTKDIIVI 471
                  **7.657**************************97 PP

>> Thioesterase  Thioesterase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.5   0.0   3.3e-32   1.5e-28       2     227 ..     701     954 ..     700     958 .. 0.82

  Alignments for each domain:
  == domain 1  score: 100.5 bits;  conditional E-value: 3.3e-32
                   EEEEE--TTCCSGGGHHHHHHCTTCEEEEEEECSTTSTSHHHCTTCHHHHHHHHHHHHHHH-SSSSEEEEEETHHHHHHHHHHHHHHHCT-SEEEEE CS
  Thioesterase   2 pLflfppagGsasvfrslasklsdpvvevlavqlpgrerdepplesieelaaeyaealrqiqpegPyalfGhSlGgllAfevArqLesqGlavkslf 98 
                   pLfl++p+ G + vf  la++++++   v+a++ +g++ +e + +si e a+ ya+ +rq+qpegPya++G+SlG++lA+ev ++Le+qG +v++l 
    EEA21142.1 701 PLFLVHPGSGDIIVFIALAAHFPTR--PVYAIRTRGYNPNEGLFSSIRETAETYANYIRQTQPEGPYAIAGYSLGSTLAYEVGKELEAQGQEVRFLA 795
                   8***********************9..********************************************************************** PP

                   EESCCCCCCHHCHHCCCHTTHHT.............................HHHHHCCTTHH.HCCTTTHCCHHHHHHHHHHHHHHHHHTCCS-TT CS
  Thioesterase  99 lidssapseteaqeasrraedee.............................fveeltdlggt.epeelledeellsellpalradyraleqyslrp 165
                    id ++++   ++ +   + d                                v+ +  +g+    ++l  d + l  +++ +    ++l++y+ + 
    EEA21142.1 796 SIDYPPRVA--HYVQDLDWIDVLlhisfylelidestmleitphmrtldreaAVKRIFNIGDVkRMQALALDAKRLVLITDITENLRLNLKSYEPVG 890
                   ***777766..44444444444456898888888888888888888888888666666666655567777777788888888888888888888888 PP

                   SCSEHHCEEEEEEGSS-CTCCCCCCCHCH....CHCTCESCEEEEEESSHCCHHHS.HHHHHHHHHH CS
  Thioesterase 166 eaaqklratlfngsddklkdldtlelaer....weqktsgevsvhvlegdhfylle.drleavleii 227
                   +  q   + +f+ +  k+++ d  + +e+    w+  ++  + +h  +g h+ +l  +++  +++i+
    EEA21142.1 891 TVDQ---MDVFVADPPKYAARDRQDWKENklgqWAGFVRTSIEFHDCPGIHAKMLNrEHTVDFARIL 954
                   8888...888888888888888666666678888888888888888999999888877777777666 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.2   1.3     4e-15   1.8e-11       3      65 ..     611     675 ..     609     677 .. 0.95

  Alignments for each domain:
  == domain 1  score: 44.2 bits;  conditional E-value: 4e-15
  PP-binding   3 lrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeef..gveiplsdlfehptlaelaa 65 
                 +++++ae+l+++ ++i++d+++fdlG++S +++ l a++++++  +++ip s+l++ pt++ +a 
  EEA21142.1 611 IQSILAELLKISSDDISLDSSIFDLGVNSFNLMLLKAKVQDALetKIDIPISVLLTEPTVGTIAS 675
                 899****************************************8888**************9985 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.0   9.1e-06     0.041       2     121 ..     703     835 ..     702     931 .. 0.65

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 9.1e-06
                    EEE--GC.....GCHHHHHHHHCCTCEEEEE--TTSTS-GGCS--HHH.CHHHHHHHCCTT..TTSE.EEEEETCHHHHHHHHHHCC........E CS
  Abhydrolase_6   2 lllHGagssassWlvapLaallaagvhvlapDlpGhGrsdpppldled.ladlaalldelaagggpv.vlvGHSlGGalalaaapla......lvv 89 
                    +l+H ++++  ++    Laa ++ +  v+a+  +G+ ++++   + ++ ++++a++++     +  +  + G+SlG +la ++++ +      +++
     EEA21142.1 703 FLVHPGSGDIIVFI--ALAAHFPTR-PVYAIRTRGYNPNEGLFSSIREtAETYANYIRQTQ--PEGPyAIAGYSLGSTLAYEVGKELeaqgqeVRF 793
                    57774444445555..777777888.55********7677777888776666677777775..5555599************66666666655333 PP

                    EEEES-...........----TTT......S----TTHHHHHHTT-C CS
  Abhydrolase_6  90 gvlldppp.........talpagl......laaalelllallallrl 121
                       +d pp               +      ++++lel++  + l+++
     EEA21142.1 794 LASIDYPPrvahyvqdlD-----WidvllhISFYLELIDESTMLEIT 835
                    355555554433322211.....123333444444444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (963 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       462  (0.0257683); expected 358.6 (0.02)
Passed bias filter:                      440  (0.0245412); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.71u 0.32s 00:00:01.03 Elapsed: 00:00:00.52
# Mc/sec: 5536.58
//
Query:       EEA21143.1  [L=587]
Description: Mob1 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.5e-26   91.1   0.1    1.2e-25   90.4   0.1    1.3  1  Mob1_phocein  Mob1/phocein family
  ------ inclusion threshold ------
       0.78    8.5   5.0        1.1    8.1   5.0    1.1  1  ALMT          Aluminium activated malate transporter


Domain annotation for each model (and alignments):
>> Mob1_phocein  Mob1/phocein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.4   0.1   1.4e-29   1.2e-25      13     166 ..     178     335 ..     169     338 .. 0.86

  Alignments for each domain:
  == domain 1  score: 90.4 bits;  conditional E-value: 1.4e-29
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxx.. RF
  Mob1_phocein  13 vklPkgedlneWlavhvvdffneinllygt.ise..fcteqscptmsagpkyeYlwadeevkkpvklsApeYidllmdwiesqlnd..lfpskag.. 102
                    + P+g+++  Wl++ ++ +  ++n l+ +  +e   c++qscp+m+a  +++Yl+a +    p +++A++Y+ +++dw+++ l++  +fps+    
    EEA21143.1 178 SHAPEGVERSLWLYELCRFLTMKVNNLIIAfFAEdpPCSQQSCPEMRAS-EWQYLCAVH--DPPKSCCAIDYCCHTLDWATNILTSpkYFPSRLTlg 271
                   568**************99999998766553553359***********7.8*******7..57889**********************666554433 PP

                   ...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Mob1_phocein 103 ...spfpknflkvvkkilkrlfrvyaHiYihHfeeiaeleleahlntcfkhfvlfvkeFkLidkkel 166
                         p+ +++++ +i++rl+r++aH++++H++ ++++e+   l  +   f ++++ ++Li ++++
    EEA21143.1 272 sesGGGPQASMRHLTNIFRRLYRIFAHAWFQHRDVFRQVENTDGLYVF---FKTVCDVYELIPQDNY 335
                   3335669***********************************999888...6789999999998876 PP

>> ALMT  Aluminium activated malate transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   5.0   0.00012       1.1     256     417 ..     365     527 ..     350     560 .. 0.63

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00012
        ALMT 256 pwkqyvkvggvlrqcaytvealhgcilseiqapeelrkkfkeelqrvslesakvlrelaesvkkmkklskveellkevkvaaeeLqskldskskLl.vn 353
                 p ++  +++ + +  a+    l++ +  + qa+ +l+       ++ s   +  ++ +ae ++++    k+e++l +v+  +e+ +s   ++s++  ++
  EEA21143.1 365 PPENNRRISVLRNDTAILTPTLSSDNPGDAQASLNLSTGATTRRHKHSPSTGSSVSTIAEVTEDHSPAAKIEQSLPKVEENVENTKSPATEESEIEkTE 463
                 5556666777777778888888888889999999999999999999999999999999999999999999999999**999999999998888542133 PP

        ALMT 354 sekweaakkkekaeeveekkeeekeseskkeeaeaveeaeseseksllkeskrslklskkesap 417
                 +++++ +++++k++ + e + e+ ++++++++ ++++e+e e++k+  +e + s+ +++ e  p
  EEA21143.1 464 APEEKSSEEEQKESDSVEPTPEKASQSEEETQPTETSETEPETDKQEESEPSGSTASTTTEVPP 527
                 3333333333333333332222222222222223333333333333333333333333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (587 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1538  (0.0857828); expected 358.6 (0.02)
Passed bias filter:                      569  (0.0317363); expected 358.6 (0.02)
Passed Vit filter:                       122  (0.00680462); expected 17.9 (0.001)
Passed Fwd filter:                        21  (0.00117129); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.85u 0.34s 00:00:01.19 Elapsed: 00:00:00.54
# Mc/sec: 3282.83
//
Query:       EEA21144.1  [L=408]
Description: CobW domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.3e-45  155.2   0.1    2.3e-45  154.3   0.1    1.4  1  cobW         CobW/HypB/UreG, nucleotide-binding domain
    7.8e-05   22.6   0.1       0.27   11.1   0.0    2.6  3  RsgA_GTPase  RsgA GTPase
     0.0003   21.2   0.1     0.0014   19.1   0.0    2.1  3  AAA_16       AAA ATPase domain
     0.0024   17.0   0.4     0.0045   16.1   0.4    1.4  1  T2SSE        Type II/IV secretion system protein
     0.0029   17.5   0.0     0.0062   16.4   0.0    1.5  1  CobW_C       Cobalamin synthesis protein cobW C-terminal doma
     0.0048   17.0   0.0      0.025   14.6   0.0    2.3  2  MMR_HSR1     50S ribosome-binding GTPase
      0.005   15.9   0.4          2    7.3   0.0    2.9  3  MeaB         Methylmalonyl Co-A mutase-associated GTPase MeaB
     0.0097   15.9   0.1      0.027   14.5   0.1    1.7  1  TsaE         Threonylcarbamoyl adenosine biosynthesis protein
  ------ inclusion threshold ------
      0.022   15.3   0.0      0.047   14.2   0.0    1.7  1  AAA_23       AAA domain
      0.034   13.9   0.2       0.15   11.8   0.0    2.1  2  AAA_29       P-loop containing region of AAA domain
      0.046   13.0   0.2        5.3    6.2   0.0    2.2  2  Septin       Septin
       0.07   13.6   0.2       0.25   11.8   0.1    2.0  2  ABC_tran     ABC transporter
      0.091   12.0   0.1       0.17   11.1   0.1    1.4  1  DUF2075      Uncharacterized conserved protein (DUF2075)
      0.098   11.9   0.0       0.18   11.1   0.0    1.4  1  Zeta_toxin   Zeta toxin
       0.12   12.3   0.1        0.2   11.5   0.1    1.3  1  ATPase_2     ATPase domain predominantly from Archaea
       0.16   12.3   0.1       0.47   10.7   0.0    1.8  2  AAA_22       AAA domain
       0.18   12.3   0.5       0.45   11.0   0.1    1.9  2  AAA_18       AAA domain


Domain annotation for each model (and alignments):
>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  154.3   0.1   2.2e-48   2.3e-45       1     175 [.      42     247 ..      42     249 .. 0.92

  Alignments for each domain:
  == domain 1  score: 154.3 bits;  conditional E-value: 2.2e-48
                 EEEEEEESTTCCHHHHHHHHHCT--SS-EEEEESS-SS.CHCCCCCCHCC.CT....EEEETTTTECCHCTT-HHHHHHHHHHHHTT-SEEEEEECTTT CS
        cobW   1 pvtvltGflGsGKTtLlnhllenraglklavivNefge.vsiDaellret.gve...ivelenGciCctlredllkelealeereerldviliEttGla 94 
                 p+t++tG+lG+GKTtLln +l++ +g+k+avi+Nefg+ ++i+++l  ++ g+e   ++++ nGciCc++++  ++++e+l++r++ +d+il+EttGla
  EEA21144.1  42 PITLVTGYLGAGKTTLLNYILTEIHGKKIAVIMNEFGDsTDIEKSLTVNQnGQEvteWLDVGNGCICCSVKDSGVQAIESLMDRRGTFDYILLETTGLA 140
                 789**********************************999*****987664444677****************************************** PP

                 THHHH..HTT.SHHHHHCCCECEEEEEEETTTH.........................CCHCCHHHHHHHHHHTSSEEEEE-HHHHCHC..HHHHHHHH CS
        cobW  95 ePapv..aft.eeelksdltldavvavvDaknl........................eaeeekieekaedqlaaadllvlnKtDlldeeallekleerl 166
                 +P  +  +f+ ++ l s++ ld++v++vDakn+                        ++   +  + a+ q+  ad++vlnK+Dl++ ++l e+ ++r+
  EEA21144.1 141 DPGNIapLFWvDDGLGSSIYLDGIVTLVDAKNIlrlldepapeettathagaehdedHHGAGPALTMAHLQISHADVIVLNKADLATPAEL-EATRQRI 238
                 *****987888****************************************9988654444566678899*******************77.******* PP

                 HHHHTTS-E CS
        cobW 167 rqlnpeakv 175
                  ++n +ak+
  EEA21144.1 239 ASINGAAKI 247
                 ****99997 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.1   0.0   0.00026      0.27      98     126 ..      39      68 ..      16     104 .. 0.74
   2 !    8.8   0.0    0.0013       1.4      49      79 ..     216     245 ..     204     267 .. 0.72
   3 ?   -3.3   0.0       6.7   7.1e+03      13      37 ..     281     305 ..     271     306 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00026
                  TT.SEEEEECSTTSSHHHHHHHHCTT---- CS
  RsgA_GTPase  98 kd.ktsvlvGqSGvGKStLinallpelelk 126
                  +   ++++ G  G+GK+tL+n +l e + k
   EEA21144.1  39 SRvPITLVTGYLGAGKTTLLNYILTEIHGK 68 
                  444689999**************9986543 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0013
                  EEEEEE-GGG--HHHHHHHHHHHHHHTTSEE CS
  RsgA_GTPase  49 pvivlnKiDlleeeeeleelkeelealgyev 79 
                   vivlnK+Dl++ +e le++++++++++ + 
   EEA21144.1 216 DVIVLNKADLATPAE-LEATRQRIASINGAA 245
                  58*************.999999999887433 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 6.7
                  EES--EEEEEEESTTTT--HHHHHH CS
  RsgA_GTPase  13 vaNvdqllivvslkepelslnlldr 37 
                   a +d  +  v+l++p++s+++l r
   EEA21144.1 281 HAHIDPRISTVALTHPKISPDQLPR 305
                  6778888888899999999998877 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   1.3e-06    0.0014      23      63 ..      40      80 ..      31     101 .. 0.84
   2 ?   -2.1   0.0       4.2   4.4e+03     134     153 ..     213     232 ..     156     250 .. 0.55
   3 ?   -2.6   0.0         6   6.3e+03      66      99 ..     302     336 ..     283     382 .. 0.65

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 1.3e-06
      AAA_16 23 rpelvllsGesGvGKsslvrellralekdggiflrgkcdql 63
                r +++l++G+ G GK++l++ +l+++ ++++ ++  ++ ++
  EEA21144.1 40 RVPITLVTGYLGAGKTTLLNYILTEIHGKKIAVIMNEFGDS 80
                4589*************************988877766665 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 4.2
      AAA_16 134 erplvlvlDdlqwadeaslq 153
                 ++  v+vl  ++ a +a l+
  EEA21144.1 213 SHADVIVLNKADLATPAELE 232
                 22335555555555554444 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 6
      AAA_16  66 aipysa.laqalareellrqlldeaesaeleawre 99 
                 ++p++  +++ + ++++++  + +a++a+ +  r 
  EEA21144.1 302 QLPRVDeWLRSILWKSVVKYSGGAAADANTQNSRF 336
                 45665557777777777777666655544444443 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.4   4.2e-06    0.0045     126     164 ..      38      76 ..      18      97 .. 0.77

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 4.2e-06
       T2SSE 126 vrerglilvsGgTgsGKttllyallkeinksderivtvE 164
                 +++  + lv+G  g GKttll+ +l+ei+ ++  +++ E
  EEA21144.1  38 ISRVPITLVTGYLGAGKTTLLNYILTEIHGKKIAVIMNE 76 
                 4555688*********************99977777655 PP

>> CobW_C  Cobalamin synthesis protein cobW C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0   5.8e-06    0.0062      26      88 ..     335     400 ..     311     406 .. 0.80

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 5.8e-06
      CobW_C  26 pegilRaKGivwlagkpdalvlqgvggrlrlepagawwaa...ededrrseLVfIGrdld.kealee 88 
                   +i R+KGi+ l +  +   +q+v+++++++  +++ ++   ++   + ++V+IGrdl   +  +e
  EEA21144.1 335 RFEIHRLKGILALTDG-TFKIIQAVREMYEIRDSEKRANKddqAEVLDHCKVVIIGRDLGtSASWQE 400
                 46799*********99.67889**********8888877766555567899*******984444555 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   2.4e-05     0.025       3      86 ..      45     171 ..      43     242 .. 0.71
   2 ?   -1.3   0.0       2.1   2.2e+03      65     102 ..     330     366 ..     319     388 .. 0.62

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 2.4e-05
                 EEEESTTSSHHHHHHHHHTS.....TEEESSSTTSSSSE.EEEEEEETTEE...................................EEEEECGGCSS.H CS
    MMR_HSR1   3 aivGrpNvGKStLinaltge.....kaivsdkpgtTrdi.negrvklkgke...................................ielvDtpGlie.g 59 
                 ++ G+  +GK+tL+n ++ e      a + ++ g  +di +  +v+ +g+e                                   ++l+ t Gl + g
  EEA21144.1  45 LVTGYLGAGKTTLLNYILTEihgkkIAVIMNEFGDSTDIeKSLTVNQNGQEvtewldvgngciccsvkdsgvqaieslmdrrgtfdYILLETTGLADpG 143
                 589**************9633333356667777777777355566655555777777777777777777777787777777777777777777754344 PP

                 HHHHH.HHHHHHHHHHCTSEEEEEEETT CS
    MMR_HSR1  60 aseek.glgkaflaleeadlillvvdas 86 
                 +     ++ + + + +  d i+ +vda+
  EEA21144.1 144 NIAPLfWVDDGLGSSIYLDGIVTLVDAK 171
                 4444455666666666667777777755 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 2.1
                 HHHHHHHHHHCTSEEEEEEETTTTCSHHHHHHHHHHHH CS
    MMR_HSR1  65 glgkaflaleeadlillvvdaseeklkpldeeleelle 102
                 + +++  ++ + + il + d +  k+ +  +e+ e+++
  EEA21144.1 330 NTQNSRFEIHRLKGILALTDGT-FKIIQAVREMYEIRD 366
                 5566666677788888888844.234444455555532 PP

>> MeaB  Methylmalonyl Co-A mutase-associated GTPase MeaB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.3   0.0    0.0019         2      34      63 ..      46      73 ..      26      80 .. 0.88
   2 ?   -0.8   0.0      0.59   6.2e+02     116     132 ..     122     139 ..     113     142 .. 0.79
   3 ?    4.9   0.0     0.011        11     169     188 ..     215     237 ..     205     270 .. 0.69

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0019
                EEE-TTSSHHHHHHHHHHHHHCTT--EEEE CS
        MeaB 34 ltGvPGaGkstlvealglelrrrGkrvavl 63
                +tG  GaGk tl++ + +e+  +Gk++av+
  EEA21144.1 46 VTGYLGAGKTTLLNYILTEI--HGKKIAVI 73
                89*************99998..699***98 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.59
                 HHHHTT.-SEEEEEEESS CS
        MeaB 116 lleaaG.fDvvlietvGv 132
                 l++  G fD +l+et G 
  EEA21144.1 122 LMDRRGtFDYILLETTGL 139
                 66666669*******996 PP

  == domain 3  score: 4.9 bits;  conditional E-value: 0.011
                 -SEEEEE---...HHHHHHHHHH CS
        MeaB 169 aDiivvnkaD...kkeaekaare 188
                 aD+iv+nkaD   ++e e +++ 
  EEA21144.1 215 ADVIVLNKADlatPAELEATRQR 237
                 9*********6433333333333 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.1   2.5e-05     0.027      10      44 ..      30      66 ..      22      74 .. 0.68

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 2.5e-05
                HHHHHHHCH..TEEEEEEESTTSSHHHHHHHHHHHTT CS
        TsaE 10 lgkklakal..gdvilLeGdLGaGKTtlvrglakalg 44
                  k+ ++ +    + l +G LGaGKTtl   ++ +++
  EEA21144.1 30 KEKETGELIsrVPITLVTGYLGAGKTTLLNYILTEIH 66
                334444433213458899************9998875 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   4.4e-05     0.047      20      39 ..      42      61 ..      22      99 .. 0.91

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 4.4e-05
      AAA_23 20 gltlItGpNGaGKTTildAi 39
                ++tl+tG  GaGKTT+l+ i
  EEA21144.1 42 PITLVTGYLGAGKTTLLNYI 61
                89***************977 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   0.00014      0.15      24      42 ..      43      61 ..      32      77 .. 0.80
   2 ?   -2.0   0.0         3   3.2e+03      34      48 ..     156     170 ..     149     175 .. 0.61

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00014
      AAA_29 24 atlltGpsGsGKSTllDAi 42
                +tl+tG  G+GK+Tll  i
  EEA21144.1 43 ITLVTGYLGAGKTTLLNYI 61
                79*************9554 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 3
      AAA_29  34 GKSTllDAiqalLvp 48 
                 G S  lD i +l  +
  EEA21144.1 156 GSSIYLDGIVTLVDA 170
                 555556666665544 PP

>> Septin  Septin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.0     0.016        17       8      53 ..      45      94 ..      41     101 .. 0.64
   2 ?    6.2   0.0     0.005       5.3     145     181 ..     217     253 ..     205     277 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.016
                EEEEBTTSSCCCCCCTTSSSS----....--------------S-EEEEE CS
      Septin  8 mvvGesglGkttlintlfetdliee....ekleeasekkkktveikkkkv 53
                +v G  g Gkttl+n ++++   ++     +    s +++k+++++++ +
  EEA21144.1 45 LVTGYLGAGKTTLLNYILTEIHGKKiaviMNEFGDSTDIEKSLTVNQNGQ 94
                799************98876555444444222334445555555555555 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.005
                 EEEESSGGGS-HHHHHHHHHHHHHHHHHTT------- CS
      Septin 145 iPviaKaDtltkeElkefKkkireeleeeeikiyklp 181
                 + v+ KaD  t  El++++++i +   + +i++ +  
  EEA21144.1 217 VIVLNKADLATPAELEATRQRIASINGAAKIHVTDHS 253
                 4599*******************99999999998744 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.1   0.00024      0.25      13      42 ..      43      72 ..      37     123 .. 0.80
   2 ?   -2.3   0.0       5.4   5.7e+03      38      67 ..     214     244 ..     205     297 .. 0.65

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00024
                EEEEEESTTSSHHHHHHHHTTSS--SEEEE CS
                xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran 13 kvaivGenGaGKStLlkllagllkpteGei 42
                ++ ++G  GaGK+tLl+ ++ + + ++  +
  EEA21144.1 43 ITLVTGYLGAGKTTLLNYILTEIHGKKIAV 72
                56788999***********99988655444 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 5.4
                 SEEEEEETTCEGGG.B-HHHCCHCEEEE-SS CS
                 xxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx RF
    ABC_tran  38 teGeilldgkdlke.qeleslrkeigvlpqe 67 
                  ++ i l+++dl +  ele +r++i+ +   
  EEA21144.1 214 HADVIVLNKADLATpAELEATRQRIASINGA 244
                 5566667777777667777777777766554 PP

>> DUF2075  Uncharacterized conserved protein (DUF2075)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.1   0.00017      0.17       3      46 ..      43      96 ..      42     100 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00017
     DUF2075  3 vvlVtGvaGtGKtvvllnllael..........eddeeertavylsvNhplvlv 46
                + lVtG  G+GKt +l+ +l+e+          e  ++   ++ l+vN++ ++v
  EEA21144.1 43 ITLVTGYLGAGKTTLLNYILTEIhgkkiavimnEFGDSTDIEKSLTVNQNGQEV 96
                579********************8888888777666688888888888877665 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00017      0.18      18      48 ..      43      72 ..      27      77 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00017
  Zeta_toxin 18 lillgGqpGAGKselaellkdelerqgnvvr 48
                + l+ G  GAGK++l++++ +e++ ++++ +
  EEA21144.1 43 ITLVTGYLGAGKTTLLNYILTEIH-GKKIAV 72
                57899*****************94.443333 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.1   0.00019       0.2      20      52 ..      41      73 ..      21     100 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00019
    ATPase_2 20 neiyfiYGpegsGKtaLlkeiienledkdkyvi 52
                 +i +++G  g GKt+Ll+ i+++ + k+  vi
  EEA21144.1 41 VPITLVTGYLGAGKTTLLNYILTEIHGKKIAVI 73
                5799******************99988776665 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00044      0.47       7      30 ..      43      66 ..      39      98 .. 0.78
   2 ?   -2.6   0.0       5.8   6.1e+03      81     105 ..     205     227 ..     170     245 .. 0.50

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00044
      AAA_22  7 ilvvtGesGtGKTtllrrlleqld 30
                i++vtG  G+GKTtll+ +l + +
  EEA21144.1 43 ITLVTGYLGAGKTTLLNYILTEIH 66
                799***************999874 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 5.8
      AAA_22  81 aleqalraravielliiDEaqhlrs 105
                 +   +l+  ++  ++++  a+   +
  EEA21144.1 205 LTMAHLQISHA-DVIVLNKADLA-T 227
                 33334444444.55666555555.4 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.1   0.00043      0.45       2      34 ..      45      75 ..      45     121 .. 0.71
   2 ?   -2.9   0.0       8.8   9.3e+03      47      63 ..     366     382 ..     356     388 .. 0.68

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00043
      AAA_18  2 lltGtpGvGKttlakeLskrlgfgvnlrdvake 34
                l+tG+ G+GKttl +++  +   + + + v+ +
  EEA21144.1 45 LVTGYLGAGKTTLLNYILTEI--HGKKIAVIMN 75
                69*************994443..4444444444 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 8.8
      AAA_18  47 deskrldedkldkllda 63 
                 d++kr+++d ++++ld 
  EEA21144.1 366 DSEKRANKDDQAEVLDH 382
                 56677777777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (408 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       641  (0.0357521); expected 358.6 (0.02)
Passed bias filter:                      567  (0.0316247); expected 358.6 (0.02)
Passed Vit filter:                        86  (0.0047967); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              17  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.48
# Mc/sec: 2560.33
//
Query:       EEA21145.1  [L=620]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-45  155.1   1.2    2.2e-45  155.1   1.2    1.6  2  HAUS6_N   HAUS augmin-like complex subunit 6 N-terminus
  ------ inclusion threshold ------
      0.054   12.3   0.0      0.097   11.5   0.0    1.3  1  Pox_A51   Poxvirus A51 protein


Domain annotation for each model (and alignments):
>> HAUS6_N  HAUS augmin-like complex subunit 6 N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  155.1   1.2   2.4e-49   2.2e-45       1     193 [.      20     215 ..      20     238 .. 0.85
   2 ?   -2.0   0.1      0.24   2.1e+03     173     192 ..     288     307 ..     254     355 .. 0.54

  Alignments for each domain:
  == domain 1  score: 155.1 bits;  conditional E-value: 2.4e-49
     HAUS6_N   1 lltnLllLgldplpd.pdksritfsedmfdkpnk.kafeivlyfLFnklDpeeakkkFrpcwPplDkkqeaeFRkalvewLkeikeegklgrlpkvvst 97 
                 +l+n++lL+ld++pd p  sr+ fs +   + ++ k +e+vly+LF ++Dp+e+k+k+rp++Ppl+  q+ ++R+al+++L+++k++g lgr ++v++t
  EEA21145.1  20 FLRNVHLLQLDQQPDwPGLSRKLFSGGQKTQTQRvKSVEWVLYQLFLLWDPSETKNKLRPFFPPLEPLQSINLRAALFRALSDLKKNGYLGRETTVRKT 118
                 789***********************777666666**************************************************************** PP

     HAUS6_N  98 lllspgGekfielLlsfssfVlkkvlkeksk....klalevreaaskkaqdlsklvaahrvslrrflrekaaadrarqkyqenaqllekkerelraele 192
                 +l++++G+kf+e+L++fs++Vl+kv+ e++     +la+    ++ + +++l +l++ah++sl+ + +e      +r+    +++ll++k rel  + +
  EEA21145.1 119 MLDDCKGPKFEEVLAVFSTAVLRKVICESQRepglRLAFTKSLTDIELEEQLVPLIIAHHASLSNTRQEQFI---IRESHDHFSKLLDEKARELSLRSK 214
                 ******************************978774444444445555667778888888887777655444...4999999**********9988777 PP

     HAUS6_N 193 e 193
                 +
  EEA21145.1 215 R 215
                 6 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.24
     HAUS6_N 173 yqenaqllekkerelraele 192
                 +q++  +le++ r l++ +e
  EEA21145.1 288 LQDLDTCLENQRRRLKRLKE 307
                 23333333333333332222 PP

>> Pox_A51  Poxvirus A51 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   1.1e-05     0.097     224     278 ..      97     150 ..      90     163 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 1.1e-05
     Pox_A51 224 lyagadkkthcliskeiankeeinddCrCCysessicvldkeellkksvCesirg 278
                 + a +d k    + +e + ++++ ddC+   +e  + v++   +l+k++Ces r+
  EEA21145.1  97 FRALSDLKKNGYLGRETTVRKTMLDDCKGPKFEEVLAVFST-AVLRKVICESQRE 150
                 5678999999999**************************96.69********996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (620 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       588  (0.032796); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.48
# Mc/sec: 3857.15
//
Query:       EEA21146.1  [L=220]
Description: HD family hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      4e-48  163.5   0.2    4.8e-48  163.2   0.2    1.1  1  HD_3      HD domain
    5.5e-14   52.3   0.1    6.8e-14   52.0   0.1    1.1  1  HD_2      HD containing hydrolase-like enzyme


Domain annotation for each model (and alignments):
>> HD_3  HD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  163.2   0.2   5.4e-52   4.8e-48       2     157 ..      39     197 ..      38     208 .. 0.92

  Alignments for each domain:
  == domain 1  score: 163.2 bits;  conditional E-value: 5.4e-52
        HD_3   2 ekLKfqkRqgwlqtgrvreesvaeHmwrvalmalllseelkekvdiarvikmfLiHDlvEiltgDiispde.lakeekeeeekeaaerilkllpee... 96 
                 e+LK++kR+gw+++g +++es+++Hm+r+a++++l++++l++k++i +++km+LiHD++E+l+gDi+++d+ ++k+ek+++e++++++i ++l  +   
  EEA21146.1  39 ERLKTTKREGWRRFGLDHAESISDHMYRMAIITMLAPPSLSSKLNIPHCTKMALIHDMAESLVGDITPVDKsITKAEKARREAATMDYIEQTLLRNvpg 137
                 89********************************************************************88********************8888777 PP

        HD_3  97 ...laeellalweEFeeretkeakfakdlDklepllqalekegdslaafeaklsqvygvsskel 157
                     + e++ +++E+e++et e+kf++d+Dk+e+llq++e+e+++ +    +ls++ +v+++++
  EEA21146.1 138 gsiSGPEIRRIFQEYEDSETLESKFVHDVDKIELLLQMVEYEREHGK----DLSEFAHVANRIT 197
                 78888*************************************99966....5566666655554 PP

>> HD_2  HD containing hydrolase-like enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.0   0.1   7.6e-18   6.8e-14       2     158 ..      34     195 ..      33     211 .. 0.79

  Alignments for each domain:
  == domain 1  score: 52.0 bits;  conditional E-value: 7.6e-18
        HD_2   2 FfallsrlkyieR..walmrntreenvaeHslevaliahalalienkkfggkldaerlallalyHDasEiitGDlptpvKyanpeireaykevEee..a 96 
                 Ff+ll+rlk+ +R  w      + e++++H +++a+i++    ++   + +kl++ ++ ++al+HD++E ++GD+ tpv  +  + ++a +e  ++   
  EEA21146.1  34 FFHLLERLKTTKRegWRRFGLDHAESISDHMYRMAIITM----LAPPSLSSKLNIPHCTKMALIHDMAESLVGDI-TPVDKSITKAEKARREAATMdyI 127
                 9************44555556899***********9974....445556679**********************9.89999988888888888777778 PP

        HD_2  97 eekllelLpee..lreeyeella.deeaeeeekklvkaaDklsalikcleelkagnke...Feeakke 158
                 e++ll+ +p      +e++++++  e+ e+ e k+v+  Dk++ l++++e ++ + k+   F++++++
  EEA21146.1 128 EQTLLRNVPGGsiSGPEIRRIFQeYEDSETLESKFVHDVDKIELLLQMVEYEREHGKDlseFAHVANR 195
                 999*****975225689999995466666779****************99776655542226655544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (220 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       444  (0.0247643); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.40u 0.21s 00:00:00.61 Elapsed: 00:00:00.36
# Mc/sec: 1851.08
//
Query:       EEA21147.1  [L=194]
Description: HIT domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      6e-25   87.8   0.0    9.4e-25   87.2   0.0    1.3  1  HIT            HIT domain
    4.7e-05   23.8   0.0    6.8e-05   23.3   0.0    1.2  1  DcpS_C         Scavenger mRNA decapping enzyme C-term binding
  ------ inclusion threshold ------
      0.076   12.7   0.0       0.12   12.1   0.0    1.3  1  GalP_UDP_tr_C  Galactose-1-phosphate uridyl transferase, C-te


Domain annotation for each model (and alignments):
>> HIT  HIT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.2   0.0   1.6e-28   9.4e-25       5      97 ..      17     109 ..      15     110 .. 0.98

  Alignments for each domain:
  == domain 1  score: 87.2 bits;  conditional E-value: 1.6e-28
                 -CCEEEE-SSEEEEE-SS-SSSSEEEEEESSTGCSGGGCCHHHHHHHHHHHHHHHHHHHTCTTCCCEEEEEEESGGGT-SSSS-EEEEEEC-T CS
         HIT   5 pstvvyeddlvlafldidpkapghlLvipkkhlselhdlteeelakllsavkkvakalqkkfknkglrvvinngahagqsvahlHiHviprre 97 
                 +s+v+y ++l++a+++ +p  pgh+Lv p++ +++++dlt++e ++l+ +v+kv + +++++ +++l++++++g +agqsv+h+H+H+ipr++
  EEA21147.1  17 TSQVFYLTPLTFALVNLKPIIPGHVLVSPRRIVPRVSDLTPDETTDLFLTVRKVGRMIERVYGATSLNIAVQDGVDAGQSVPHVHTHIIPRKK 109
                 589****************************************************************************************87 PP

>> DcpS_C  Scavenger mRNA decapping enzyme C-term binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.3   0.0   1.1e-08   6.8e-05      26     103 ..      30     108 ..      17     116 .. 0.82

  Alignments for each domain:
  == domain 1  score: 23.3 bits;  conditional E-value: 1.1e-08
                 EE-SS-SSSEEEEEEESS---SGGG--TTTTTHHHHHHHHHHHHHHHTT-T.-EEEEE--SCCCT--S-S--EEEEE.. CS
      DcpS_C  26 lkDikpkaklhllvipkrdikslrdLtkehlpllkemrekakkvieekyne.vdaeelrvgvhyqPsvyhlHlHvisld 103
                 l  +kp  + h+lv p+r ++ + dLt+++   l   ++k+  +ie+ y +      ++ gv + +sv h+H H+i  +
  EEA21147.1  30 LVNLKPIIPGHVLVSPRRIVPRVSDLTPDETTDLFLTVRKVGRMIERVYGAtSLNIAVQDGVDAGQSVPHVHTHIIPRK 108
                 5566777788***************************************66433334666***************9754 PP

>> GalP_UDP_tr_C  Galactose-1-phosphate uridyl transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0     2e-05      0.12      48     119 ..      36     105 ..      16     112 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 2e-05
                    -STT-EEEEESS--SSGGG--HHHHHHHHHHHHHHHHHHHHHCT.S---..EEEEEE---SCCCTTTT--EEEEE CS
  GalP_UDP_tr_C  48 kWPfevlllrkaevkslaeladeekedlaailkklarkydnlfe.tsfe..ysmGlhqaplnaeednswlHaHfe 119
                    + P +vl+ +++ v+++++l+  e++dl  +++k+ r  +  +  ts +    +G+     +a ++   +H+H+ 
     EEA21147.1  36 IIPGHVLVSPRRIVPRVSDLTPDETTDLFLTVRKVGRMIERVYGaTSLNiaVQDGV-----DAGQSVPHVHTHII 105
                    568899******************************99999998433320023344.....33333344666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (194 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       313  (0.0174578); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.30s 00:00:00.82 Elapsed: 00:00:00.51
# Mc/sec: 1134.69
//
Query:       EEA21148.1  [L=904]
Description: Rad4 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.3e-35  121.5   0.2    2.3e-35  121.5   0.2    2.0  2  Rad4            Rad4 transglutaminase-like domain
    3.7e-29  100.9   0.1      8e-29   99.9   0.1    1.6  1  BHD_3           Rad4 beta-hairpin domain 3
    2.9e-15   55.8   0.1    5.7e-15   54.9   0.1    1.5  1  BHD_1           Rad4 beta-hairpin domain 1
    1.3e-13   51.6   0.3    1.3e-13   51.6   0.3    2.7  2  BHD_2           Rad4 beta-hairpin domain 2
    7.8e-06   26.3   0.0    3.7e-05   24.1   0.0    2.2  2  Transglut_core  Transglutaminase-like superfamily
  ------ inclusion threshold ------
       0.12   12.5   0.6       0.37   11.0   0.6    1.9  1  DUF3420         Domain of unknown function (DUF3420)


Domain annotation for each model (and alignments):
>> Rad4  Rad4 transglutaminase-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.4   0.6       4.8   1.4e+04      20      38 ..     197     215 ..     191     220 .. 0.50
   2 !  121.5   0.2   7.6e-39   2.3e-35      14     146 ..     369     523 ..     350     524 .. 0.90

  Alignments for each domain:
  == domain 1  score: -4.4 bits;  conditional E-value: 4.8
                 ....--TTHHHHHTTS-SE CS
        Rad4  20 etkkkkkrlkdkdlpypvy 38 
                 +tk kkk +k+k++ +   
  EEA21148.1 197 DTKGKKKGSKKKESAKTRN 215
                 3444444444444444444 PP

  == domain 2  score: 121.5 bits;  conditional E-value: 7.6e-39
                 S---......--TTHHHHHTTS-SEEEEEEETTTTEEEEEESSSS-EE.....SS--TTS--...TGGGS----EEEEE-TTS-EEE-HHHH-T..TCC CS
        Rad4  14 dkskkketkkkkkrlkdkdlpypvyWvEvfspekkkwisvdplvgsti.....ekkeilepl...aekakqvlsYVvAfdsdgsakDVTrRYls.dysn 103
                 ++++  ++++ k+++ d+dlp+pvyW+Ev+sp+++++++vdplv+ +      e  +++ep+   a+kakqv++YVvA +sdg+akDVT+RYl+ ++++
  EEA21148.1 369 TDEDGDTQTSAKTSQFDRDLPFPVYWTEVVSPITHEVVPVDPLVLTNPvaanpEMVAAFEPRggrADKAKQVIAYVVAHSSDGTAKDVTTRYLRrQTWP 467
                 233345667788888899**************************98889*********************************************9**** PP

                 CCHGGGSGG.............GSHHHHHHHHHHHHHH--S---H..HHHHHHHHH CS
        Rad4 104 sktkklrve.............kskeekkWfesvlrplekrnkertevdalEdael 146
                 +ktk+ r++               + ++ Wf+++++ + +  ++rt+vd++Eda++
  EEA21148.1 468 GKTKGYRLPmekltirmsrrgpTYTIDYHWFRETMKGYVRSDNQRTAVDDIEDAKD 523
                 *******************99999999**************************987 PP

>> BHD_3  Rad4 beta-hairpin domain 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.9   0.1   2.7e-32     8e-29       1      75 [.     664     736 ..     664     737 .. 0.94

  Alignments for each domain:
  == domain 1  score: 99.9 bits;  conditional E-value: 2.7e-32
                 ----TTS-EE-SSGGGS-TTEEEEE-TTHHHHHHHCT---EEEEEEEEE-SS-EE..EEEEEEEEEGGGHHHHHH CS
       BHD_3   1 vPkNeygnieifkpsmlPegavhislkgaakaakklgidyapAvvGFefkgrrgkgiPvidGivVaeedeeavle 75 
                 +PkNeygni++f+p+m+P+ga hi+  g+ +++kklgidya+Av+GFef+  ++ ++Pvi+G+vVaee+++ v++
  EEA21148.1 664 IPKNEYGNIDCFVPTMVPRGATHIPYSGTVRICKKLGIDYAEAVTGFEFG--SKMAVPVIEGVVVAEENADLVRD 736
                 8************************************************9..34447***************987 PP

>> BHD_1  Rad4 beta-hairpin domain 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.9   0.1   1.9e-18   5.7e-15       5      51 .]     538     591 ..     535     591 .. 0.90

  Alignments for each domain:
  == domain 1  score: 54.9 bits;  conditional E-value: 1.9e-18
       BHD_1   5 PenlqdfKnhplYvLerhLkrnEvlhpdakpvgvfkk.......kepVYrRsdV 51 
                  ++lq +K + ++vLer+L+r+E+l+p+ak v++f +       +e+VYrR dV
  EEA21148.1 538 TDTLQSLKASTEFVLERFLRREEALRPGAKVVRKFVTgkgdkakEENVYRRADV 591
                 489********************************656667777*********9 PP

>> BHD_2  Rad4 beta-hairpin domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.6   0.3   4.5e-17   1.3e-13       2      64 .]     596     657 ..     595     657 .. 0.97
   2 ?   -3.1   0.3       5.4   1.6e+04      37      37 ..     806     806 ..     769     827 .. 0.55

  Alignments for each domain:
  == domain 1  score: 51.6 bits;  conditional E-value: 4.5e-17
       BHD_2   2 SaerWyrlGReVkpgelPvKrvksraktarkkredekkeeeeeeeegevpLYgewQTelYvpP 64 
                 Sae+W+++GR  k ge P+Krv+ ra+t  +kre e+    ++++++ ++LY++ QTe ++pP
  EEA21148.1 596 SAESWHKEGRRPKIGEAPLKRVPIRAVTLMRKREVEEL-TRQTGQKPLQGLYARYQTEFIIPP 657
                 9************************************9.8888*******************9 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 5.4
       BHD_2  37 e 37 
                 e
  EEA21148.1 806 E 806
                 1 PP

>> Transglut_core  Transglutaminase-like superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.0   1.2e-08   3.7e-05      40      80 ..     293     333 ..     257     383 .. 0.83
   2 ?   -2.8   0.0       2.8   8.4e+03       6      52 ..     532     577 ..     530     585 .. 0.69

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 1.2e-08
  Transglut_core  40 srdaeavletgkGncedfaslfvallRalGipaRvvtgyls 80 
                     +++ +a+ e+++G     a+lf+allRalGi+aR+v+++++
      EEA21148.1 293 RHEFRALAEKRQGSRDVGAQLFTALLRALGIEARLVSNLQP 333
                     555778888999*************************9987 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 2.8
  Transglut_core   6 eltagakdplekakaiyewvrknveysaprrtpgsrdaeavletgkG 52 
                     +++++++d l+ +ka  e+v +++  +++   pg + +++++ tgkG
      EEA21148.1 532 KIVKKETDTLQSLKASTEFVLERFLRREEALRPGAKVVRKFV-TGKG 577
                     688899999999999999999888887444444444444443.4555 PP

>> DUF3420  Domain of unknown function (DUF3420)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.6   0.00012      0.37       6      33 ..     163     191 ..     161     215 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00012
     DUF3420   6 iLEKeLPievlakIkelRlksslp.slsP 33 
                 iL K+LP  + + Ik  R++s l+ +  P
  EEA21148.1 163 ILRKQLPEGIQKEIKRWRVASALDpPPPP 191
                 799********************964333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (904 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       714  (0.0398237); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.69u 0.29s 00:00:00.98 Elapsed: 00:00:00.46
# Mc/sec: 5923.52
//
Query:       EEA21149.1  [L=182]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.1e-28   99.1   0.0    2.7e-28   98.8   0.0    1.1  1  CoA_binding_2  CoA binding domain


Domain annotation for each model (and alignments):
>> CoA_binding_2  CoA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.8   0.0   1.5e-32   2.7e-28       2     107 ..      40     150 ..      39     165 .. 0.88

  Alignments for each domain:
  == domain 1  score: 98.8 bits;  conditional E-value: 1.5e-32
                    -EEEET--S-TTSHHHHHHHHHHHHT--EEEESSS-SEETTEES----T.....T--.....EEEE-S-HHHHGGGHHHHHHH--SEEEE-TT--- CS
  CoA_binding_2   2 tiaVvGasdnpgkfgykvlryllehglpvvpVnpkeeeilgekvyaslae.dpepvd.....lvdvftppeatpeivkealalgakavwlqpgsed 91 
                    ++aV+Ga ++p++fgyk+++++++h+lpv+p++p+e++i    +   +a+ + + +      +++++tpp +t++++k+a+++g++avw+qpg+++
     EEA21149.1  40 RFAVAGANNDPHRFGYKIFAWYHQHSLPVTPIHPREPTIRLPSQEYPVAStP-KSLPsptetSLSFVTPPPVTLQLLKQAHEVGIPAVWFQPGTYN 134
                    58***************************************77666666534.333345568********************************** PP

                    HHHHHHHHHTT-EEE. CS
  CoA_binding_2  92 eeaaelaeeagirvvg 107
                    +e++e+a+++   v+g
     EEA21149.1 135 DEVLEYARDNFPAVIG 150
                    ********97666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (182 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       245  (0.013665); expected 358.6 (0.02)
Passed bias filter:                      211  (0.0117686); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.42
# Mc/sec: 1303.82
//
Query:       EEA21150.1  [L=380]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (380 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       629  (0.0350828); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2683.52
//
Query:       EEA21151.1  [L=556]
Description: hypothetical protein PMAA_049510 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (556 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       385  (0.0214736); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.46
# Mc/sec: 3653.36
//
Query:       EEA21152.1  [L=401]
Description: dimethyladenosine transferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.1e-57  193.7   0.0    4.1e-57  193.3   0.0    1.1  1  RrnaAD           Ribosomal RNA adenine dimethylase
    0.00057   20.5   0.0     0.0014   19.3   0.0    1.6  1  Methyltransf_25  Methyltransferase domain
    0.00073   20.1   0.0     0.0016   19.1   0.0    1.5  1  Methyltransf_11  Methyltransferase domain


Domain annotation for each model (and alignments):
>> RrnaAD  Ribosomal RNA adenine dimethylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  193.3   0.0   6.9e-61   4.1e-57       2     235 ..      33     254 ..      32     270 .. 0.94

  Alignments for each domain:
  == domain 1  score: 193.3 bits;  conditional E-value: 6.9e-61
                 GCCXXGCG--EE--HHHHHHHHHHH-GGTTSEEEEES-TTTCCHHHHHCC-SEEEEE-S-HHHHHHHHCHTT...TCCCEEEE-S-CCGHHHHHHHCTT CS
      RrnaAD   2 nklrksygqnflknkkvineIldklnleekltvleigpGkGilTeeLakrakqvvvlElderLakllqkkls...kdeklkvvhqDflkfetpeevtek 97 
                 +k++++ gq++lkn+ +++ I+dk+n++e   v   gpG+G+lT++++  ak+ +++Eld+r+a++l+k ++    ++kl ++  Df k +++e     
  EEA21152.1  33 FKFNTDIGQHILKNPGIADAIVDKANIKEHEVV---GPGTGVLTRRILAKAKSCTAIELDPRMAAELTKMVQgtpMQKKLRIILGDFIKVDLKE----- 123
                 79***************************9996...***********************************99999******************..... PP

                 TCCCCEEEEEEE--TTTHHHHHHHHHHGGGGCEEEEEEEEEHHHHHHHH--TTSTT-SHHHHHHHHHEEEEEEEEC-GGCECS--SSSEEEEEEEE-SS CS
      RrnaAD  98 dsihqeflvvanlPyeistqlvkqlleesrfglvkmllwlqkefarrllarpgskkrsrlsvlreaftdvklvakveksifsPppkvdsalvelerkde 196
                   i+    +++n+Py+is++lv++ll ++r++ + ++l++q+efa+rl+arpg+  +srlsv++++ +   +++kv+k++fsPpp+v+s++v++e+++ 
  EEA21152.1 124 --IGHFDVFISNTPYQISSPLVFKLLAMPRPP-RVSVLMVQREFAQRLIARPGDAMYSRLSVNAQFHAICSHILKVGKNNFSPPPQVESSVVKIEPRPD 219
                 ..55555789*********************7.88999************************************************************* PP

                 -S--S-HHHHHHHHHHHHCTTTSBCCCHCCCTSTCHHHH CS
      RrnaAD 197 dlpqkdlkkyesvvrkllnrkrktlstslksllpggelq 235
                 + p+ ++++++ ++r+++nrk+ktl+ s+   + ++ ++
  EEA21152.1 220 R-PDISWEELDGMLRICFNRKNKTLRSSF---FVKQVRE 254
                 9.8***********************994...4555544 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.0   2.3e-07    0.0014       4      73 ..      65     134 ..      64     148 .. 0.85

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 2.3e-07
                      ET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHHTTT..TEEEEESBCCGBSS.STTTEEEEEEEST CS
  Methyltransf_25   4 lGcGtGrltlalakrlgkakvtgvDiseemleaareraeeegl..nvefvqgdaedlpf.edgsfDlvvssga 73 
                      +G GtG lt++++++   ++ t+++++++m ++  + ++   +  +++++ gd+ ++++ e g+fD+ +s+ +
       EEA21152.1  65 VGPGTGVLTRRILAKA--KSCTAIELDPRMAAELTKMVQGTPMqkKLRIILGDFIKVDLkEIGHFDVFISN-T 134
                      799**********996..9*******************8765588*********998853778******95.3 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   2.6e-07    0.0016       3      68 ..      65     133 ..      64     142 .. 0.94

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 2.6e-07
                      ET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-..EEEETTEECCCTSS-T.T-EEEEEEE CS
  Methyltransf_11   3 vGcGtGrlaealakrgarvvgvDlskemlklakekaseegl..kvefvvadaeklpfed.nsfDlvvss 68 
                      vG GtG l++ +  +++++++++l+++m +   + +++ ++  k++++ +d+ k+ +++ + fD+ +s+
       EEA21152.1  65 VGPGTGVLTRRILAKAKSCTAIELDPRMAAELTKMVQGTPMqkKLRIILGDFIKVDLKEiGHFDVFISN 133
                      8************999*************999999999888999***************99****9997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (401 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       558  (0.0311228); expected 358.6 (0.02)
Passed bias filter:                      453  (0.0252663); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.59u 0.26s 00:00:00.85 Elapsed: 00:00:00.46
# Mc/sec: 2592.17
//
Query:       EEA21153.1  [L=351]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (351 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       478  (0.0266607); expected 358.6 (0.02)
Passed bias filter:                      222  (0.0123822); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.24s 00:00:00.68 Elapsed: 00:00:00.41
# Mc/sec: 2553.99
//
Query:       EEA21154.1  [L=350]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.6e-22   78.3  10.8    6.6e-22   78.3  10.8    2.0  2  FA_hydroxylase  Fatty acid hydroxylase superfamily


Domain annotation for each model (and alignments):
>> FA_hydroxylase  Fatty acid hydroxylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.1      0.17   3.1e+03      68      82 ..      88     103 ..      46     128 .. 0.51
   2 !   78.3  10.8   3.7e-26   6.6e-22       3     133 .]     181     327 ..     179     327 .. 0.78

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.17
  FA_hydroxylase  68 plsalll.vlvlaall 82 
                        a++l +++++a+ 
      EEA21154.1  88 GVAAFVLyTVAFKAIA 103
                     2222333333333333 PP

  == domain 2  score: 78.3 bits;  conditional E-value: 3.7e-26
  FA_hydroxylase   3 lallledfveYwvHrllHrvkllwrrlHkvHHsseaptalaalrahple.alllalllllll...lllg...plsalllvlvlaallelliHsg. 89 
                     l+ ++ df++Yw+Hrl+H+v+ lw+ +H++HH +++p++l +l+a + + ++ +a + ll +    l+g    +  ++l++ +  + el +Hsg 
      EEA21154.1 181 LYGIILDFWFYWYHRLMHDVDALWK-YHRTHHLTKHPNPLLTLYADVEQeFWDIAGVPLLTYgsmKLMGmpmGFYEWWLCHQYIVFSELAGHSGl 274
                     678999*************999***.*************87777765440333334444444222555564556669999**************9 PP

  FA_hydroxylase  90 .....lhvslgwllerl..latpraHrlHHskneeg..nfgvllslwDrlfgT 133
                          +  +l+wl+++l      + H+lHH+   ++  n+g+ ++lwDr+fgT
      EEA21154.1 275 riyarTASPLTWLMKLLgaELVIEDHDLHHRTGWKKshNYGKQTRLWDRIFGT 327
                     99988778888988666667889********8764445**************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (350 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       327  (0.0182386); expected 358.6 (0.02)
Passed bias filter:                      215  (0.0119917); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.29s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 2314.63
//
Query:       EEA21155.1  [L=530]
Description: sugar transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.8e-22   77.7  34.0    3.4e-14   52.5  17.2    2.1  2  MFS_1     Major Facilitator Superfamily
    9.8e-18   64.2  15.5    3.5e-17   62.4  15.5    1.9  1  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.5  17.2   3.8e-18   3.4e-14       3     268 ..      68     405 ..      66     408 .. 0.76
   2 !   31.1  12.5   1.2e-11   1.1e-07      44     176 ..     393     525 ..     388     530 .] 0.86

  Alignments for each domain:
  == domain 1  score: 52.5 bits;  conditional E-value: 3.8e-18
       MFS_1   3 laaflsalarsilgpalplalaedlg..ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.sslwlllvlrvlqGlg 98 
                 ++++  ++a+++l+p++++++ ++ g  + p+    l     +g +++++++G+  d fGr++ + l++ ++a+++l+++ + +++ +++v+ +l ++g
  EEA21155.1  68 FVVIGFGWASDNLWPIVTSLILTAVGneFKPAHNAYLSLSQNIGLLIGAIFWGFGCDLFGRKWAFNLTIGITAVFGLVAA-GsPNFAAICVFAALWSVG 165
                 6677788888889999988665555544457777788899***********************************77777.525555************ PP

       MFS_1  99 agalfpagaaliadwfpkeergraigllsa....gfslGailg.pllggllasslg..........Wravfyilaivsllafvlfllllpeepperkrk 182
                  g+ +p+  a++ +  p++++ + + +ls+    +  ++++++ pllg + ++             Wr+ +++++++s+++fv+ +++++  ++++   
  EEA21155.1 166 VGGNLPVDSAIFLEFLPPSHQYLLT-VLSIdwafAQLVASLIAwPLLGDYTCQESDadctrsknfgWRYFMIAMGGLSMVMFVIRFAFFTIYESPKYLM 263
                 ******************6655544.4444333255555577778888888866668999999999*****************6667775555555555 PP

       MFS_1 183 spkeee..................................................kgtgpaplvpawkallkdpvlw....illialllfffgfsgll 227
                 s  ++                                                      ++ +++   ++l++   l     ++ ++++++++g+ ++ 
  EEA21155.1 264 SRGKDAeavavvhevarrngktsdltledltkydalaersedgvraqqtsavaaleRNLERVSFTH-VRSLFSTARLGistsMVTAIWAFIGLGYPLYN 361
                 555555567888888888888888889999999999999999988776666666655555555555.888998888855667677777777779999** PP

       MFS_1 228 tllplylqevlgls.......glllaglllallalvgailallagrls 268
                 ++lp + q ++g +           ++    +++++g+++++l+g+l+
  EEA21155.1 362 AFLPYI-QATRGADfgdgstyI---TYRNEVIISVLGIPGCILGGFLI 405
                 ****97.999999998875441...44334566666777788888775 PP

  == domain 2  score: 31.1 bits;  conditional E-value: 1.2e-11
       MFS_1  44 gaavaslplGrlsd..rfGrrrvlllglllfalglllll.fasslwlllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpl 139
                 + + + +++G+l++  rfGr+  l l+ +l++++ l+++  a+++ +ll   +   + + +++++ +a++ ++fp ++rg +++++++++ +  ++ p+
  EEA21155.1 393 LGIPGCILGGFLIElpRFGRKGALALSTTLTGVF-LYAStTATTSNALLGWNCAYNFVSNIMYAVLYAYTPEVFPTKDRGTGNAIAASANRIFGVMSPI 490
                 55666788999999889*****************.66662335555***************************************************** PP

       MFS_1 140 lggllasslgWravfyilaivsllafvlfllllpeep 176
                 ++ +    l+  a+ y+ +++++ a++l+lll +e++
  EEA21155.1 491 IAMFAN--LNSAAPVYVSGALFIAAGLLALLLPFESR 525
                 *88877..888999***********998777766655 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.4  15.5     4e-21   3.5e-17      54     430 ..     107     515 ..      99     523 .. 0.76

  Alignments for each domain:
  == domain 1  score: 62.4 bits;  conditional E-value: 4e-21
                 THHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHH CS
    Sugar_tr  54 iflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGil 152
                 + ++G +iG++f g+  d fGRk+++  ++ ++ + +++ a ++   ++ +++v   l  +gvG+   + +    E+ p+++ + l+ +    ++f +l
  EEA21155.1 107 SQNIGLLIGAIFWGFGCDLFGRKWAFNLTIGITAVFGLVAAGSP---NFAAICVFAALWSVGVGGNLPVDSAIFLEFLPPSHQYLLT-VLSIDWAFAQL 201
                 6689****************************************...9**********************************87665.5679******* PP

                 HHHHHHHHH.HTSS-...........TTHHHHHHHCCHHHHHHHHHHG...GGS---HHHHHHTT-HHHHHHHHHH...HHHC.....HHHHHHHHHHH CS
    Sugar_tr 153 vaaifglgl.nktsn...........adgwrillglqlvpallllill...lflPESPrylvekgkeeeakevlak...lrge.....edadrelaeek 228
                 va+ + + l  +++            + gwr+++     +++++++++   +++ ESP yl+++gk+ ea +v+ +    +g+      ++  + ++ +
  EEA21155.1 202 VASLIAWPLlGDYTCqesdadctrskNFGWRYFMIAMGGLSMVMFVIRfafFTIYESPKYLMSRGKDAEAVAVVHEvarRNGKtsdltLEDLTKYDALA 300
                 ******9988444444899*****99999**998888888888877653337899******************99975433336555522222333333 PP

                 HHHHHHHH.........................HTTHHHHSH...HHHHHHHHHHHHHH.TTHHHHHHHTTTHHHHSS-THH.......HHHHHHHHHH CS
    Sugar_tr 229 dsleaeqeee....................kaswkellssktvrqrlligvvlqifqql.tGinaimyysptifenlglsks.......llvtiivgvv 299
                 +  e                           + +++l+s+   r  + + +v++i+ +   G+     + p+i  + g +         +   +i++v+
  EEA21155.1 301 ERSED----GvraqqtsavaalernlervsFTHVRSLFST--ARLGISTSMVTAIWAFIgLGYPLYNAFLPYIQATRGADFGdgstyitYRNEVIISVL 393
                 33333....2344477788888888887788888888888..5567777777777765437888888899***99999886666866655556899999 PP

                 HHHHHHHHHHHHH..HS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHH CS
    Sugar_tr 300 nfvatfvaiflvd..rfGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnw 396
                  +  ++ + fl++  rfGR+  l l+++  +         ++l+ +++   s++++   + + ++ ++    v++ + +E+fp++ R+++ aia+ +n 
  EEA21155.1 394 GIPGCILGGFLIElpRFGRKGALALSTT-LTG--------VFLYASTTATTSNALLGWNCAYNFVSNIMY-AVLYAYTPEVFPTKDRGTGNAIAASANR 482
                 9999999999999889****44444332.222........444444433345566666666666666443.46677889******************** PP

                 HHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHH CS
    Sugar_tr 397 lanflisllfpiiteaigggyvflvfaglavlfi 430
                 ++ +   ++ +++  ++  ++v++  a + ++++
  EEA21155.1 483 IFGVMSPIIAMFANLNSA-APVYVSGALFIAAGL 515
                 ***********9999999.666665555554443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (530 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       739  (0.0412181); expected 358.6 (0.02)
Passed bias filter:                      458  (0.0255452); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 3464.41
//
Query:       EEA21156.1  [L=284]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.4e-25   88.7   0.2    6.4e-25   88.2   0.2    1.2  1  HRI1      Protein HRI1


Domain annotation for each model (and alignments):
>> HRI1  Protein HRI1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.2   0.2   3.5e-29   6.4e-25       1     197 [.      22     235 ..      22     262 .. 0.73

  Alignments for each domain:
  == domain 1  score: 88.2 bits;  conditional E-value: 3.5e-29
                 EEEEEEEEESSS--.B..--B--EEE-T--EEEEEEBSS--CC.CTTS-..EEEEEEE-GGGEEEE-SSE.E.EEEE--SEEHHH...........HCT CS
        HRI1   1 siskRksirwppeepsEptsTlvLtspsgrfVDiRilkepesekeeepeplleWafaGtststsettegelvshstfthwiDsrveeaaaDeGdmyelp 99 
                 s+ +R+sirwppe+++E+t+T v++   + fVD+R+ k++++         l+Wa+aG++   +++      +++tf h+i+sr + ++ D G +++l+
  EEA21156.1  22 SLLTRVSIRWPPEDAYENTETTVISVN-NFFVDLRVEKQTRK---------LDWAIAGVRLMDQND-----SRRVTFLHTINSRNTFQHIDTGLFTQLA 105
                 5789*******************9776.9********88532.........********9988888.....68************88************ PP

                 TS-EEEEEEE-.TT-...S--EEEEEEEEEB-TTSSS-BB--.......---EEEEEE-S.T...........EEEEEEETTEEEEEEETTGGGEEEEE CS
        HRI1 100 sgltlEkGemvnpat...gkveeYeElWrdldpakteeeeev.......kvrcvvleledse....dde....rGlvvrvGqycqGilrkgekeltveR 180
                 +g+ +E G+m++p        ++YeE+Wr+  p + ++++ +       +    v  +++s+    + e    + ++ r+G    +i + + + +   R
  EEA21156.1 106 NGDEMESGTMIRPGDpqgAFPRQYEEVWRQRRPINVPGQNIAwilegagS---RVSLTQNSDgvgsE-EskevETFLARLGSVYIAIRQPT-RIVQTPR 199
                 ***********98775536679********99999999887788886432...22222222233441.23457889999998888886553.2444444 PP

                 EEE...................-TTS-.EEEEEEES CS
        HRI1 181 wew...................eedegewkrtvriG 197
                  +                     + + +w +++  G
  EEA21156.1 200 ANGsfsfqkfgdiegvsvrheeYAGKRGWVEKFVTG 235
                 444445555555555555555434455566666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (284 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       271  (0.0151152); expected 358.6 (0.02)
Passed bias filter:                      242  (0.0134977); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.47
# Mc/sec: 1821.11
//
Query:       EEA21157.1  [L=589]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (589 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       651  (0.0363099); expected 358.6 (0.02)
Passed bias filter:                      596  (0.0332422); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.68u 0.32s 00:00:01.00 Elapsed: 00:00:00.50
# Mc/sec: 3552.58
//
Query:       EEA21158.1  [L=1023]
Description: hypothetical protein PMAA_049580 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.6e-16   59.2   0.0    1.1e-15   58.2   0.0    1.5  1  AAA       ATPase family associated with various cellular acti
     0.0008   19.8   0.7       0.01   16.2   0.7    2.5  1  AAA_16    AAA ATPase domain
  ------ inclusion threshold ------
       0.02   15.1   0.0      0.093   13.0   0.0    2.1  2  AAA_22    AAA domain


Domain annotation for each model (and alignments):
>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.2   0.0   1.9e-19   1.1e-15       1     130 [.     667     786 ..     667     788 .. 0.94

  Alignments for each domain:
  == domain 1  score: 58.2 bits;  conditional E-value: 1.9e-19
                 EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTS CS
         AAA   1 vllyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksrsgseseeeervvnqLlteldgvkkk 99 
                 +ll+G pG+GKT++a+  a +   ++l i + +l   + +e e+k++e+f+ a+e    +++++DE+d +  +r +++++ ++ +v+++l+ l+ ++  
  EEA21158.1 667 ILLHGVPGVGKTSTAECAAISNRKPLLPITCGDLG-LTPKEVEDKLKEIFRLAQEWG--CVMLLDEADVFLAQR-SATDTTRNALVSVFLRTLEYYEG- 760
                 69*******************99***********9.889**************9998..***************.78889999999999999999999. PP

                 SSTEEEEEEESSGGGSTHHHHSTTSSEEEET CS
         AAA 100 eskvivigatnrpdkldpallrgRfdrkiei 130
                     i+ ++tnr+  +d+a++ +R+ + ++ 
  EEA21158.1 761 ----ILFLTTNRVGVFDEAFR-SRIHMSLYY 786
                 ....99***************.9*9988775 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.7   1.7e-06      0.01      20      47 ..     660     687 ..     651     854 .. 0.76

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.7e-06
      AAA_16  20 rsgrpelvllsGesGvGKsslvrellra 47 
                 ++g + ++ll+G +GvGK+s +++++ +
  EEA21158.1 660 NKGNGVIILLHGVPGVGKTSTAECAAIS 687
                 567789****************998733 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   1.6e-05     0.093       7      66 ..     666     717 ..     660     766 .. 0.88
   2 ?   -2.2   0.0      0.77   4.6e+03      70     110 ..     930     980 ..     912     981 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 1.6e-05
      AAA_22   7 ilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsst.sskdllrellralgl 66 
                 i++++G +G+GKT +++  + ++         r++++ +t+  ++ ++k++  +l +++ l
  EEA21158.1 666 IILLHGVPGVGKTSTAECAAISN---------RKPLLPITCGDLGlTPKEVEDKLKEIFRL 717
                 89******************999.........99999****99999999988777777665 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.77
      AAA_22  70 a....erlsseellealeqalrarav.......ielliiDEaqhlrseeale 110
                 +    +++ss+ l ++  q++++  +       +++  +D++q    +++l+
  EEA21158.1 930 TygqrAPQSSSNLGAQKLQHSQRGPMsglssypVHAQRLDNIQAA-GMRQLN 980
                 133445679999999999999988887777777777777777776.666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1023 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       474  (0.0264376); expected 358.6 (0.02)
Passed bias filter:                      458  (0.0255452); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.73u 0.28s 00:00:01.01 Elapsed: 00:00:00.46
# Mc/sec: 6681.07
//
Query:       EEA21159.1  [L=250]
Description: hypothetical protein PMAA_049590 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (250 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       534  (0.0297841); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1675.37
//
Query:       EEA21160.1  [L=294]
Description: hypothetical protein PMAA_049600 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (294 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       760  (0.0423894); expected 358.6 (0.02)
Passed bias filter:                      524  (0.0292264); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.30s 00:00:00.81 Elapsed: 00:00:00.48
# Mc/sec: 1855.96
//
Query:       EEA21161.1  [L=677]
Description: LipA and NB-ARC domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
      0.016   14.8   0.5      0.034   13.8   0.5    1.5  1  Abhydrolase_8  Alpha/beta hydrolase


Domain annotation for each model (and alignments):
>> Abhydrolase_8  Alpha/beta hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.5   1.9e-06     0.034      73     121 ..     141     190 ..     100     195 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.9e-06
  Abhydrolase_8  73 aPagaskevatddrAaagAaeLnallrdlrats.vpgqhlallgHSYGSl 121
                     Pa  +++ a +++A+++  e + ++ +l a+  v+++h ++l HS G +
     EEA21161.1 141 GPASGGWKKAATEHAQKAFQEARHFVGGLIAHPtVSNKHYTILRHSHGVV 190
                    46999************************99987**************87 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (677 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       586  (0.0326845); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.66u 0.30s 00:00:00.96 Elapsed: 00:00:00.47
# Mc/sec: 4361.26
//
Query:       EEA21162.1  [L=154]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (154 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       303  (0.0169); expected 358.6 (0.02)
Passed bias filter:                      297  (0.0165653); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.36u 0.22s 00:00:00.57 Elapsed: 00:00:00.36
# Mc/sec: 1278.84
//
Query:       EEA21163.1  [L=390]
Description: O-acetylhomoserine (thiol)-lyase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.6e-95  319.2   0.0    3.2e-95  318.9   0.0    1.0  1  Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
    7.3e-08   32.1   2.0    2.2e-07   30.5   1.9    1.7  2  DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family
    3.7e-06   26.1   0.3    5.9e-06   25.5   0.3    1.3  1  Aminotran_5      Aminotransferase class-V
    1.2e-05   24.8   0.1    2.2e-05   23.9   0.1    1.3  1  Beta_elim_lyase  Beta-eliminating lyase
     0.0016   17.3   0.1     0.0024   16.8   0.1    1.2  1  GDC-P            Glycine cleavage system P-protein
  ------ inclusion threshold ------
      0.021   14.4   0.3      0.033   13.7   0.3    1.3  1  NmrA             NmrA-like family


Domain annotation for each model (and alignments):
>> Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  318.9   0.0   1.1e-98   3.2e-95      35     382 .]       9     388 ..       2     388 .. 0.94

  Alignments for each domain:
  == domain 1  score: 318.9 bits;  conditional E-value: 1.1e-98
                      HHCTTCSSS-SBTTT--HHHHHHHHHHHHHHT-SEEEEESSHHHHHHHHHHTTS-TTEEEEEESTSSHHHHHHHHHTHHHTTCEEEEESTTSHH CS
  Cys_Met_Meta_PP  35 eafageekgyeYsRsgnptrsvleeriaaLeggeaalavssGmaAiaaailallkaGdeivvsddlYggtqrllkkvlkklgievkfvdtsdle 128
                      + fag+++++ YsR+gnpt+ v+e+riaaLegg+aal  ssG aA  +ai al+ aG++iv+s ++ + t+ ++k+ l+  gi+v+f+d +d++
       EEA21163.1   9 DIFAGKAEDFAYSRLGNPTSAVFEQRIAALEGGAAALPASSGEAARWMAIAALAMAGENIVASATISEETYTMFKYRLPTQGITVTFIDINDTD 102
                      44899999************************************************************************************** PP

                      HHHHHCCTTEEEEEEESS-TTTT----HHHHHHHHHHTT-EEEEEGTT.THTTTS-GGGGT-SEEEEETTTTTTCSSS--EEEEEESSCHHHHH CS
  Cys_Met_Meta_PP 129 elekaikentklvylEtptnpllkvvDiekiaklakkagvlvvvDntf.aspllqrplklgaDivvhSaTKylgGhsdvvaGvivvkgkeelkk 221
                      ++++ai+e+t++vy+E++++  l+++Di ++a++a++agv++vvDnt  ++++l+rp+++gaDiv++S++ ++ G +++v G++v++gk+ +k+
       EEA21163.1 103 SIRNAIDEKTRAVYIESISSLGLQIADISAVASVAHAAGVPLVVDNTAgVAGYLIRPIDHGADIVINSTSEWVTGTGTTVSGIVVDSGKFPWKT 196
                      ***********************************************84588****************************************** PP

                      HHHHHH................................HHHT-B--HHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHTSTTEEEEE-TTSTT CS
  Cys_Met_Meta_PP 222 elkflq................................nalGavlspfdawlllrGlkTLslRlerhqenAlkvAefLekhpkvekvyYpglps 283
                      + ++++                                ++ G+ l+pf+a   l Gl  Ls R++rh++nAl +A +L+ ++kv kv +pgl +
       EEA21163.1 197 NSSRFPhltepspgyhgmnfveqfgniayilymrmailRDGGPCLNPFAASFALAGLGSLSPRVDRHNSNALSLAAWLQMNEKVAKVVFPGLTT 290
                      *999999*************************************************************************************** PP

                      STTHHHHHHHSSSG-S...EEEEEESSHH.HHHHHHHHC-SSSEECSS-SSSS-EEEETTTTTTTTSCHHHHHHTTS-TTEEEEE--SS-HHHH CS
  Cys_Met_Meta_PP 284 hpqhelakkqlkgagg...vlsFelksee.ekakkfvdnlklfslaeslGgveslielpasmthasipkeereaagvtddliRlsvGiEdvdDl 373
                      h+ +   kk+l++ +g   vl F l+++  ek++++vdnlkl++l++ lG  ++li lp   +     +e    ++  d ++R+svG+E++dD+
       EEA21163.1 291 HRTFSRTKKYLRQNAGygaVLYFGLQEGGaEKVAALVDNLKLIKLSNGLGTPQTLIYLPEGRSAS---REGI--KDADDAIVRVSVGLEHIDDI 379
                      ******9998876655556******988779****************************876543...2332..3346889************* PP

                      HHHHHHHHH CS
  Cys_Met_Meta_PP 374 iaDlkqale 382
                      i+Dl+qale
       EEA21163.1 380 INDLEQALE 388
                      *******96 PP

>> DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.5   1.9   7.5e-11   2.2e-07      22     147 ..      25     150 ..      14     166 .. 0.83
   2 ?   -1.5   0.0      0.41   1.2e+03     221     271 ..     240     290 ..     239     305 .. 0.80

  Alignments for each domain:
  == domain 1  score: 30.5 bits;  conditional E-value: 7.5e-11
                      SHHHHHHHHHHHHHHT-SEEEEESSHHHHHHHHHHHTTTTTT-EEEEESS....S-THHHHHHHHTT-EEEEE-B-TTTSSB-GGGCGGG--TT CS
  DegT_DnrJ_EryC1  22 gpeveeFEkafaaylgvkhaiavssGtaAlhlaLralgvgpgdeVIvpsl....tFvatanavlelgakpvfvDvdpdtynidpaaieaaiter 111
                      +p+ + FE+++aa  g + a++ ssG aA  +a+ al +  g+ ++  ++    t++         g ++ f+D++      d ++i++ai e+
       EEA21163.1  25 NPTSAVFEQRIAALEGGAAALPASSGEAARWMAIAALAMA-GENIVASATiseeTYTMFKYRLPTQGITVTFIDIN------DTDSIRNAIDEK 111
                      688899******************************9998.6665554432333677777777789*********9......99********** PP

                      EEEEEEB-GGG...B---HHHHHHHHHHCT-EEEEE-TT CS
  DegT_DnrJ_EryC1 112 tkaIlpVhlyG...qvadmdalkaiaakhglkvieDaAh 147
                      t+a+ +  + +   q+ad++a+  +a++ g++++ D   
       EEA21163.1 112 TRAVYIESISSlglQIADISAVASVAHAAGVPLVVDNTA 150
                      ***99755543334899*****************99765 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.41
                      B-BHHHHHHHHHHHCTHHHHHHHHHHHHHHHHHHHHTCCCCEESCGGTTSS CS
  DegT_DnrJ_EryC1 221 rlteiqAAiglaqLerldelvarRreiaelykeeLaelegtaelttpketk 271
                      +l+ ++A+  la L  l+  v+r + +a  +   L+  e++a++ +p  t+
       EEA21163.1 240 CLNPFAASFALAGLGSLSPRVDRHNSNALSLAAWLQMNEKVAKVVFPGLTT 290
                      577788999999999999999999999999999999999888888887776 PP

>> Aminotran_5  Aminotransferase class-V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.5   0.3     2e-09   5.9e-06     112     210 ..      89     182 ..      48     191 .. 0.87

  Alignments for each domain:
  == domain 1  score: 25.5 bits;  conditional E-value: 2e-09
                  HTEEEEEEEBETTSCBEGGGHHHH--TTEEEEEEESBETTTTE.B--HHHHHHHHHHTT-EEEEE-TTTTTTS---HHHHTESEEEEETTTTTSSTT- CS
  Aminotran_5 112 tgakvkvipldeegeldldelekllnektklvaithvsnvtGt.iqpveeigklakkkgalvlvDaaqavghipidvkklgvDflafsghKllgPtGi 208
                  +g++v++i +      d+d ++++++ekt++v+i  +s+  G  i ++ +++++a+++g+ ++vD +++v  + i   + g+D++  s+   +  tG+
   EEA21163.1  89 QGITVTFIDI-----NDTDSIRNAIDEKTRAVYIESISSL-GLqIADISAVASVAHAAGVPLVVDNTAGVAGYLIRPIDHGADIVINSTSEWVTGTGT 180
                  5677777777.....4678889***************975.655*****************************************9999888888888 PP

                  EE CS
  Aminotran_5 209 Gv 210
                  +v
   EEA21163.1 181 TV 182
                  76 PP

>> Beta_elim_lyase  Beta-eliminating lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.1   7.4e-09   2.2e-05      30     168 ..      24     148 ..       7     152 .. 0.89

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 7.4e-09
                      --HHHHHHHHHHHHHTT-SEEEEES-HHHHHHHHHHHH--TTEEEEEETT-HHHHSST.THHHHCC--EEEEE-EBTTTBE-HHHHHHHS--S- CS
  Beta_elim_lyase  30 edktvnrLedavaelfgkeaalfvpqGtaAnsillkillqrgeevivtepahihfdet.gaiaelagvklrdlknkeaGkmdlekleaaikevg 122
                      +++t  ++e+++a+l g +aal++ +G aA  +++++l+  ge+++++ +   ++++  +     +g++++ +++++      +++++ai+e  
       EEA21163.1  24 GNPTSAVFEQRIAALEGGAAALPASSGEAARWMAIAALAMAGENIVASATISEETYTMfKYRLPTQGITVTFIDIND-----TDSIRNAIDE-- 110
                      6999**********************************************999999995555555999888888877.....9*********.. PP

                      TTS-EEEEEEEESSBTTTTTB---HHHHHHHHHHHHHCT-EEEEEE CS
  Beta_elim_lyase 123 aheekiklisltvTnntagGqvvsleelrevaaiakkygiplhlDg 168
                          k+++++++          ++++ + +va +a++ g+pl++D 
       EEA21163.1 111 ----KTRAVYIESISSL----GLQIADISAVASVAHAAGVPLVVDN 148
                      ....689*****99887....599********************95 PP

>> GDC-P  Glycine cleavage system P-protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.1   8.2e-07    0.0024     140     258 ..      50     172 ..      35     178 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 8.2e-07
                 HHHH.HHHHHH-SSS--EEEEETTS-HHHHHHHHHHHGGGT-EEEEE-GGG--S-.....S-EEEEEEEES-TTS.B----HHHHHHHHHTT-EEEEEE CS
       GDC-P 140 aEAv.llaaraskkkakkvvvdkkvhpqtlevlktrakglgieivevdlteekvtd..kekevagvlvqypnteG.riedlkelvekakkkkslvvvaa 234
                 +EA+  +a +a     +++v ++++ ++t ++ k r  ++gi +   d+ +++       +++ +v +   +  G +i d++++++ a+   + +vv  
  EEA21163.1  50 GEAArWMAIAALAMAGENIVASATISEETYTMFKYRLPTQGITVTFIDINDTDSIRnaIDEKTRAVYIESISSLGlQIADISAVASVAHAAGVPLVVDN 148
                 455414555666666789**************************9999888776654577999*****999999968****************999987 PP

                 -TTGGGTB--HHHHT-SEEEEE-T CS
       GDC-P 235 dllaLtllkpPgelgaDivvGsaq 258
                      + l  P + gaDiv+ s+ 
  EEA21163.1 149 TAGVAGYLIRPIDHGADIVINSTS 172
                 776667777899********9885 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.3   1.1e-05     0.033      39      97 ..      85     145 ..      48     154 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.1e-05
                 HHHHSTTEEEES-TT-HHHHHHHHTT.-SEEEE---GG.S-HHHHHHHHHHHHHHHS-SEE CS
        NmrA  39 slkeaGvelvkgdlddkeslvealkg.vdvvfsvtgfy.skeiedgkklvdAakeaGvkhf 97 
                  l ++G ++   d++d +s+++a+++   +v++   +  + +i+d ++++++a +aGv+ +
  EEA21163.1  85 RLPTQGITVTFIDINDTDSIRNAIDEkTRAVYIESISSlGLQIADISAVASVAHAAGVPLV 145
                 57789*******************752667777666557*******************865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (390 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       504  (0.0281109); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.38
# Mc/sec: 3079.21
//
Query:       EEA21164.1  [L=383]
Description: O-acetylhomoserine (thiol)-lyase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.4e-88  296.2   0.0    3.2e-88  295.9   0.0    1.0  1  Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
    7.1e-08   32.1   2.0    2.2e-07   30.6   1.9    1.7  2  DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family
    3.7e-06   26.1   0.3    5.7e-06   25.5   0.3    1.3  1  Aminotran_5      Aminotransferase class-V
    1.2e-05   24.8   0.1    2.1e-05   23.9   0.1    1.3  1  Beta_elim_lyase  Beta-eliminating lyase
     0.0016   17.3   0.1     0.0023   16.8   0.1    1.1  1  GDC-P            Glycine cleavage system P-protein
  ------ inclusion threshold ------
       0.02   14.4   0.3      0.032   13.8   0.3    1.3  1  NmrA             NmrA-like family


Domain annotation for each model (and alignments):
>> Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  295.9   0.0   1.1e-91   3.2e-88      35     370 ..       9     376 ..       2     378 .. 0.94

  Alignments for each domain:
  == domain 1  score: 295.9 bits;  conditional E-value: 1.1e-91
                      HHCTTCSSS-SBTTT--HHHHHHHHHHHHHHT-SEEEEESSHHHHHHHHHHTTS-TTEEEEEESTSSHHHHHHHHHTHHHTTCEEEEESTTSHH CS
  Cys_Met_Meta_PP  35 eafageekgyeYsRsgnptrsvleeriaaLeggeaalavssGmaAiaaailallkaGdeivvsddlYggtqrllkkvlkklgievkfvdtsdle 128
                      + fag+++++ YsR+gnpt+ v+e+riaaLegg+aal  ssG aA  +ai al+ aG++iv+s ++ + t+ ++k+ l+  gi+v+f+d +d++
       EEA21164.1   9 DIFAGKAEDFAYSRLGNPTSAVFEQRIAALEGGAAALPASSGEAARWMAIAALAMAGENIVASATISEETYTMFKYRLPTQGITVTFIDINDTD 102
                      44899999************************************************************************************** PP

                      HHHHHCCTTEEEEEEESS-TTTT----HHHHHHHHHHTT-EEEEEGTT.THTTTS-GGGGT-SEEEEETTTTTTCSSS--EEEEEESSCHHHHH CS
  Cys_Met_Meta_PP 129 elekaikentklvylEtptnpllkvvDiekiaklakkagvlvvvDntf.aspllqrplklgaDivvhSaTKylgGhsdvvaGvivvkgkeelkk 221
                      ++++ai+e+t++vy+E++++  l+++Di ++a++a++agv++vvDnt  ++++l+rp+++gaDiv++S++ ++ G +++v G++v++gk+ +k+
       EEA21164.1 103 SIRNAIDEKTRAVYIESISSLGLQIADISAVASVAHAAGVPLVVDNTAgVAGYLIRPIDHGADIVINSTSEWVTGTGTTVSGIVVDSGKFPWKT 196
                      ***********************************************84588****************************************** PP

                      HHHHHH................................HHHT-B--HHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHTSTTEEEEE-TTSTT CS
  Cys_Met_Meta_PP 222 elkflq................................nalGavlspfdawlllrGlkTLslRlerhqenAlkvAefLekhpkvekvyYpglps 283
                      + ++++                                ++ G+ l+pf+a   l Gl  Ls R++rh++nAl +A +L+ ++kv kv +pgl +
       EEA21164.1 197 NSSRFPhltepspgyhgmnfveqfgniayilymrmailRDGGPCLNPFAASFALAGLGSLSPRVDRHNSNALSLAAWLQMNEKVAKVVFPGLTT 290
                      *999999*************************************************************************************** PP

                      STTHHHHHHHSSSG-S...EEEEEESSHH.HHHHHHHHC-SSSEECSS-SSSS-EEEETTTTTTTTSCHHHHHHTTS-TTEEEEE--SS-H CS
  Cys_Met_Meta_PP 284 hpqhelakkqlkgagg...vlsFelksee.ekakkfvdnlklfslaeslGgveslielpasmthasipkeereaagvtddliRlsvGiEdv 370
                      h+ +   kk+l++ +g   vl F l+++  ek++++vdnlkl++l++ lG  ++li lp   +     +e    ++  d ++R+svG+E++
       EEA21164.1 291 HRTFSRTKKYLRQNAGygaVLYFGLQEGGaEKVAALVDNLKLIKLSNGLGTPQTLIYLPEGRSAS---REGI--KDADDAIVRVSVGLEHI 376
                      ******9998876655556******988779****************************876543...2332..3346889********98 PP

>> DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.6   1.9   7.3e-11   2.2e-07      22     147 ..      25     150 ..      14     166 .. 0.83
   2 ?   -1.5   0.0       0.4   1.2e+03     221     271 ..     240     290 ..     239     305 .. 0.80

  Alignments for each domain:
  == domain 1  score: 30.6 bits;  conditional E-value: 7.3e-11
                      SHHHHHHHHHHHHHHT-SEEEEESSHHHHHHHHHHHTTTTTT-EEEEESS....S-THHHHHHHHTT-EEEEE-B-TTTSSB-GGGCGGG--TT CS
  DegT_DnrJ_EryC1  22 gpeveeFEkafaaylgvkhaiavssGtaAlhlaLralgvgpgdeVIvpsl....tFvatanavlelgakpvfvDvdpdtynidpaaieaaiter 111
                      +p+ + FE+++aa  g + a++ ssG aA  +a+ al +  g+ ++  ++    t++         g ++ f+D++      d ++i++ai e+
       EEA21164.1  25 NPTSAVFEQRIAALEGGAAALPASSGEAARWMAIAALAMA-GENIVASATiseeTYTMFKYRLPTQGITVTFIDIN------DTDSIRNAIDEK 111
                      688899******************************9998.6665554432333677777777789*********9......99********** PP

                      EEEEEEB-GGG...B---HHHHHHHHHHCT-EEEEE-TT CS
  DegT_DnrJ_EryC1 112 tkaIlpVhlyG...qvadmdalkaiaakhglkvieDaAh 147
                      t+a+ +  + +   q+ad++a+  +a++ g++++ D   
       EEA21164.1 112 TRAVYIESISSlglQIADISAVASVAHAAGVPLVVDNTA 150
                      ***99755543334899*****************99765 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.4
                      B-BHHHHHHHHHHHCTHHHHHHHHHHHHHHHHHHHHTCCCCEESCGGTTSS CS
  DegT_DnrJ_EryC1 221 rlteiqAAiglaqLerldelvarRreiaelykeeLaelegtaelttpketk 271
                      +l+ ++A+  la L  l+  v+r + +a  +   L+  e++a++ +p  t+
       EEA21164.1 240 CLNPFAASFALAGLGSLSPRVDRHNSNALSLAAWLQMNEKVAKVVFPGLTT 290
                      577788999999999999999999999999999999999888888887776 PP

>> Aminotran_5  Aminotransferase class-V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.5   0.3   1.9e-09   5.7e-06     112     210 ..      89     182 ..      48     191 .. 0.87

  Alignments for each domain:
  == domain 1  score: 25.5 bits;  conditional E-value: 1.9e-09
                  HTEEEEEEEBETTSCBEGGGHHHH--TTEEEEEEESBETTTTE.B--HHHHHHHHHHTT-EEEEE-TTTTTTS---HHHHTESEEEEETTTTTSSTT- CS
  Aminotran_5 112 tgakvkvipldeegeldldelekllnektklvaithvsnvtGt.iqpveeigklakkkgalvlvDaaqavghipidvkklgvDflafsghKllgPtGi 208
                  +g++v++i +      d+d ++++++ekt++v+i  +s+  G  i ++ +++++a+++g+ ++vD +++v  + i   + g+D++  s+   +  tG+
   EEA21164.1  89 QGITVTFIDI-----NDTDSIRNAIDEKTRAVYIESISSL-GLqIADISAVASVAHAAGVPLVVDNTAGVAGYLIRPIDHGADIVINSTSEWVTGTGT 180
                  5677777777.....4678889***************975.655*****************************************9999888888888 PP

                  EE CS
  Aminotran_5 209 Gv 210
                  +v
   EEA21164.1 181 TV 182
                  76 PP

>> Beta_elim_lyase  Beta-eliminating lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.1   7.2e-09   2.1e-05      30     168 ..      24     148 ..       7     152 .. 0.89

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 7.2e-09
                      --HHHHHHHHHHHHHTT-SEEEEES-HHHHHHHHHHHH--TTEEEEEETT-HHHHSST.THHHHCC--EEEEE-EBTTTBE-HHHHHHHS--S- CS
  Beta_elim_lyase  30 edktvnrLedavaelfgkeaalfvpqGtaAnsillkillqrgeevivtepahihfdet.gaiaelagvklrdlknkeaGkmdlekleaaikevg 122
                      +++t  ++e+++a+l g +aal++ +G aA  +++++l+  ge+++++ +   ++++  +     +g++++ +++++      +++++ai+e  
       EEA21164.1  24 GNPTSAVFEQRIAALEGGAAALPASSGEAARWMAIAALAMAGENIVASATISEETYTMfKYRLPTQGITVTFIDIND-----TDSIRNAIDE-- 110
                      6999**********************************************999999995555555999888888877.....9*********.. PP

                      TTS-EEEEEEEESSBTTTTTB---HHHHHHHHHHHHHCT-EEEEEE CS
  Beta_elim_lyase 123 aheekiklisltvTnntagGqvvsleelrevaaiakkygiplhlDg 168
                          k+++++++          ++++ + +va +a++ g+pl++D 
       EEA21164.1 111 ----KTRAVYIESISSL----GLQIADISAVASVAHAAGVPLVVDN 148
                      ....689*****99887....599********************95 PP

>> GDC-P  Glycine cleavage system P-protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.1   7.9e-07    0.0023     140     258 ..      50     172 ..      35     178 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 7.9e-07
                 HHHH.HHHHHH-SSS--EEEEETTS-HHHHHHHHHHHGGGT-EEEEE-GGG--S-.....S-EEEEEEEES-TTS.B----HHHHHHHHHTT-EEEEEE CS
       GDC-P 140 aEAv.llaaraskkkakkvvvdkkvhpqtlevlktrakglgieivevdlteekvtd..kekevagvlvqypnteG.riedlkelvekakkkkslvvvaa 234
                 +EA+  +a +a     +++v ++++ ++t ++ k r  ++gi +   d+ +++       +++ +v +   +  G +i d++++++ a+   + +vv  
  EEA21164.1  50 GEAArWMAIAALAMAGENIVASATISEETYTMFKYRLPTQGITVTFIDINDTDSIRnaIDEKTRAVYIESISSLGlQIADISAVASVAHAAGVPLVVDN 148
                 455414555666666789**************************9999888776654577999*****999999968****************999987 PP

                 -TTGGGTB--HHHHT-SEEEEE-T CS
       GDC-P 235 dllaLtllkpPgelgaDivvGsaq 258
                      + l  P + gaDiv+ s+ 
  EEA21164.1 149 TAGVAGYLIRPIDHGADIVINSTS 172
                 776667777899********9885 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.3   1.1e-05     0.032      39      97 ..      85     145 ..      48     154 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.1e-05
                 HHHHSTTEEEES-TT-HHHHHHHHTT.-SEEEE---GG.S-HHHHHHHHHHHHHHHS-SEE CS
        NmrA  39 slkeaGvelvkgdlddkeslvealkg.vdvvfsvtgfy.skeiedgkklvdAakeaGvkhf 97 
                  l ++G ++   d++d +s+++a+++   +v++   +  + +i+d ++++++a +aGv+ +
  EEA21164.1  85 RLPTQGITVTFIDINDTDSIRNAIDEkTRAVYIESISSlGLQIADISAVASVAHAAGVPLV 145
                 57789*******************752667777666557*******************865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (383 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       453  (0.0252663); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 2692.43
//
Query:       EEA21165.1  [L=353]
Description: D-amino acid oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.3e-33  114.6   0.0    9.3e-33  114.3   0.0    1.1  1  DAO       FAD dependent oxidoreductase


Domain annotation for each model (and alignments):
>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.3   0.0   5.2e-37   9.3e-33       3     352 .]      10     346 ..       9     346 .. 0.77

  Alignments for each domain:
  == domain 1  score: 114.3 bits;  conditional E-value: 5.2e-37
                 EEECTSHHHHHHHHHHHHT.T...EEEEESSSSTTSSGGGSSEEEEESSS....STHHSTHHHHHHHHHHHHHHHHHHHHHSSTTSEEEEEEEEEESSH CS
         DAO   3 viiGGGiiGlstAyeLarr.g...VtllekgdiagsgaSgrnsgllhsgl....rylpeaselarlslealeelreleeelgididyrrtGllslaade 93 
                 vi G+G++Gl+tA+eL +r +   V+++ k+  +g  +S   +  ++++     + + ++  + ++ + +++ +++++++  +++++rr     +++++
  EEA21165.1  10 VILGAGVVGLTTALELKTRfPtsqVIVVAKH-LPG-DQSVEYTSPWAGANwlsmA-TDNG-VQEEWDAVSFKKFEKISQQ-SPECGVRRMDIRAIFDSP 103
                 9***************88875789*******.***.6666666666554447543.4444.4449999999*******99.9*************9665 PP

                 HHHHHHHHHHHHHHHTTTTE.EEEEH.HHHHHHS.TTSTTTSEE..EEETTEEEEEHHHHHHHHHHHHHHTT-EEEESECEEEEEEEETCEEEEE.EEC CS
         DAO  94 eelealdkllallleaglda.ellda.eevrele.palpgllga..lfypdtgqvdpakltaalaraaealGveilegtevtgleeedgkvwgve.rtt 186
                  e +++   + +++   + + +l+ +  ev + e p+     g+   ++ +t  ++ + ++++l+ ++ ++G+++++  +  ++        g++ +  
  EEA21165.1 104 IENAGI---VSQGT-GKIWYeKLVGGlCEVPKHElPQ-----GSnfGYDLSTFMINVQSYLPWLQVQVLKAGIDLRRS-QYDDI-------NGLFdN-- 183
                 333333...22221.2232214777754577777442.....2221256667999**********************8.77776.......455422.. PP

                 TEEEEEEEEEEE--GGGHHHHHTTCTT.TSEEEEEEEEEEEEEECCTHSTGSGCSEEEEEEEETTTTEEEEEE.TTSEEEEEESSEEETTCSSTSCSHH CS
         DAO 187 pgendaadavVnaaGawsdllgllkel.dlpispvrgqvlvlkplseklvspaailpvpetdddgrgvyvtpr.kdgrvlvGgtadeesgdddpevdee 283
                      +a++  n++G++s  l   k + d+ ++p++gq+l ++ +s++l++    +  p ++  ++ +yv+pr + g+v++Gg     +g  d  vd +
  EEA21165.1 184 ---FPTANTFLNCTGLGSYSL---KGVeDHNVYPTKGQILLVETPSKPLEK--MYFRSP-KRVASDTTYVFPRyPHGGVVLGGCR--LDGVWDGNVDLD 271
                 ...234799********9877...777689************776665544..556666.788899999999768899******8..8888888***** PP

                 HHHHHHHHHHHHSGGG.....CGEEEEEEEEEEETTSSEEEEEEE..TEEEEEEEEECTTTHHHHHHHHHHHHHHH CS
         DAO 284 didellealrklfPql.....gdvlrkwaGlrplpdglpligetp..gvkglylatGhsghGltlapatGkllael 352
                  ++++ +++ +l+P+l      +vl++ +Glrp + g+p i      g k +++++G+ g G++ +++++k++++l
  EEA21165.1 272 FAEDIKRRCCALCPDLgkpedLKVLYHAVGLRPSRKGGPRIEA-QfyGDKMVVHNYGAAGAGYQASWGMAKHAVDL 346
                 ***************74452344889*******99******99.557789**********************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (353 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       273  (0.0152267); expected 358.6 (0.02)
Passed bias filter:                      255  (0.0142228); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.24s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2559.23
//
Query:       EEA21166.1  [L=622]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.5e-21   75.9   0.0    5.1e-21   74.9   0.0    1.4  1  Fungal_trans  Fungal specific transcription factor domain
    2.9e-08   33.7  11.6    5.1e-08   32.9  11.6    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.9   0.0   5.7e-25   5.1e-21       4     265 ..     106     350 ..     104     352 .. 0.83

  Alignments for each domain:
  == domain 1  score: 74.9 bits;  conditional E-value: 5.7e-25
  Fungal_trans   4 ffsnfhpqf....pilhkpsflpktssenssksayasplll.lailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilq 95 
                   ffs   pqf    + +h+p+f               +plll  ai++l+al + +++ e  +s+++  +  +   l  ++l+    ss+ + ++ + 
    EEA21166.1 106 FFSS--PQFslvgHAFHRPTFEGRQ--------FLEQPLLLrVAICSLAALQLADDDLERYFSREDGPDVSNRLALIGQTLS--RDSSFHPTVENIL 190
                   5555..8887788899*****9988........667777777*****************98888887767776677777777..8888888899999 PP

  Fungal_trans  96 sLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddl 192
                   +  ll + e+  ++ +l++++ g+a+r+a+ l+L+++  +        +++ e+e+rrR  w+aF+lD++++ ++ rp  +  ++++++LPc  +++
    EEA21166.1 191 ANALLGWRELIAGSGNLAWLYTGLAIRMAQVLRLGKEYHQR-------HPAVERERRRRAMWTAFILDRLVSYVMARPQAIGVHKLRIQLPCPNHHY 280
                   ***********************************888775.......56666**************************8899**999999999998 PP

  Fungal_trans 193 wesddaseetlvetklsneeksrkiasfllaLkkilskiagsllsiekqlqqrdlqseklswveeleraldnW 265
                    + +  s+ +  + +l  e ++++i  +++++ +++++  + l+++    + ++++ + +  ++++e  +++W
    EEA21166.1 281 VFGEAYSGPNIHQ-PLLGEVSNDDILAYVIRVINLWGGCTD-LFANLAIGETSSSA-QFEIELRQMELTIETW 350
                   7766666666544.447889999999999999999999888.88887777777777.6666666666666666 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.9  11.6   5.7e-12   5.1e-08       1      31 [.      38      68 ..      38      73 .. 0.94

  Alignments for each domain:
  == domain 1  score: 32.9 bits;  conditional E-value: 5.7e-12
                SS-HHHHHCT---STSSSS-HHHHHCTHHHC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCt 31
                +aC +Cr++KvKC++ kP C nC++   eC+
  EEA21166.1 38 QACLPCRRRKVKCNGAKPRCHNCARFDDECQ 68
                69****************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (622 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       473  (0.0263818); expected 358.6 (0.02)
Passed bias filter:                      375  (0.0209158); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.43
# Mc/sec: 4351.59
//
Query:       EEA21167.1  [L=365]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.5e-38  132.8   0.0    1.9e-38  132.4   0.0    1.1  1  Abhydrolase_3  alpha/beta hydrolase fold
     0.0027   16.7   0.3      0.005   15.8   0.3    1.5  1  COesterase     Carboxylesterase family
  ------ inclusion threshold ------
       0.13   12.9   0.0       0.19   12.3   0.0    1.3  1  Abhydrolase_6  Alpha/beta hydrolase family
       0.18   11.4   0.0       0.31   10.6   0.0    1.3  1  Peptidase_S15  X-Pro dipeptidyl-peptidase (S15 family)


Domain annotation for each model (and alignments):
>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.4   0.0   4.3e-42   1.9e-38       2     210 ..     119     339 ..     118     340 .. 0.91

  Alignments for each domain:
  == domain 1  score: 132.4 bits;  conditional E-value: 4.3e-42
                    EEE--STTTS--TTTTHHHHHHHHHHHTSEEEEEE---TTTS-TTHHHHHHHHHHHHHHHTHHHHTETTCEEEEEEETHHHHHHHHHHHHHHHTT- CS
  Abhydrolase_3   2 vyfHGGGfvlgsldthdalcrelakelgavvvsvdYrlAPehpfPaavedalaalrwlaeqawelgadpsrivlaGdSaGGnlaaavalrardege 97 
                    + fHGGGfv+gs+  + ++c  l ++l  vvv v+Yr  Pe+ +   +eda+a+l+w+++++ +l++ +s++ l+G SaGG l+  + + ard+ +
     EEA21167.1 119 INFHGGGFVFGSFHADAKFCMTLRDRLSLVVVDVNYRHCPETIMGKNIEDAWAVLSWVRDSSGKLNIIKSSVSLGGISAGGYLSCILQHLARDD-N 213
                    57***********************************************************99******************************9.6 PP

                    --EEEEEEESE.-SST...SSTTSHHHHHCHHTTTSSSSCHHHHHHHHHHHSSGGGGGST.......TTSGGGCS-SST---EEEEEETT-TTHHH CS
  Abhydrolase_3  98 pkvagqvliyP.vtdl...ertesesikkaeeladgplltraaldlfwrlylpeadrddp.......laspllaedlsglpptlvvvaefDplrde 182
                    ++++ ++   P vtd    ++ e + +++ ++++++pll+ a+l +f ++  p++++d+        +++p+ a+++++l+ t++++ae Dplrde
     EEA21167.1 214 VPLKLVIPAVPpVTDCcsyKKLEDSPYESFRRYSRAPLLNWARLSYFQQYAFPDDKVDEIrslwpewWLAPIKAPNFTNLCDTFLITAEIDPLRDE 309
                    789999988888888788866666777677999999***9999998777777988888877788888*******9********************* PP

                    HHHHHHHHHHTT--E..EEEEETTEETTGG CS
  Abhydrolase_3 183 geayaerlraagvev..elieyegmvHgfa 210
                    ge+y ++l aa  ++  e+ +y g++H f+
     EEA21167.1 310 GEDYGKKLVAAALPTinEVLRYLGVPHPFM 339
                    *********99887655999*******997 PP

>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.3   1.1e-06     0.005     103     196 ..     113     199 ..      54     214 .. 0.77

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 1.1e-06
                 SSEEEEEEE--STTTS-BGCG..S-THHHHHHHTSEEEEE----HHHHH-B-SSTTSBS-HHHHHHHHHHHHHHHHGGGGTEEEEEEEEEEETHHH CS
  COesterase 103 kklPVlVwihGggfqtgsase..ydgsaLaaegnvivVtinYRlGvlGFlstgdeeapGNvGllDqvlALrWVkenIasFGGdpervtlfGesAGa 196
                   ++V + +hGggf++gs +     + +L ++ +++vV +nYR  +   +  +         + D  + L WV++   + +  +++v l G sAG+
  EEA21167.1 113 GPYSVHINFHGGGFVFGSFHAdaKFCMTLRDRLSLVVVDVNYRHCPETIMGKN---------IEDAWAVLSWVRDSSGKLNIIKSSVSLGGISAGG 199
                 5579999***********977655677888888**********8765555442.........4566666666666666666666666666666666 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   4.1e-05      0.19      64     191 ..     187     317 ..     117     363 .. 0.54

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 4.1e-05
                    TTSEEEEEETCHHHHHHHHHHCC......EEEEES-..----TTT.......S----TTHHHHHHTT-CCCCHCCHS-HSCCCCHHHCCCCHCHCC CS
  Abhydrolase_6  64 ggpvvlvGHSlGGalalaaapla....lvvgvlldppptalpagl.......laaalelllallallrllawlsreplprlfladedadaawrarl 148
                       v l G S GG+l++ +++la    +  ++++ +   ++p ++        + + e ++++ ++   l w ++     +++     +a   + +
     EEA21167.1 187 KSSVSLGGISAGGYLSCILQHLArddnVPLKLVIPA---VPPVTDccsykklEDSPYESFRRYSRAPL-LNWARL-----SYFQ---QYAFPDDKV 270
                    34479******************7666333344444...44444444455544444444444444333.366643.....5555...444455555 PP

                    CGHHHHCCHHCHTT..CCHHTT-TTGCEEECTT-C..HHHHCHHCCC CS
  Abhydrolase_6 149 arlaallaglgllp..aaawadlpvpllvlggeDp..lvprllerll 191
                    ++ + l++ ++l p  a++++ l  ++l+ ++ Dp     + + + l
     EEA21167.1 271 DEIRSLWPEWWLAPikAPNFTNLCDTFLITAEIDPlrDEGEDYGKKL 317
                    55555555555443334455555555544344455442222222222 PP

>> Peptidase_S15  X-Pro dipeptidyl-peptidase (S15 family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   6.9e-05      0.31      79     135 ..     162     225 ..     157     233 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 6.9e-05
                    TTTHHHHHHHHHHHHHH...C.TTEEEEEEEEEECHHHHHHHHH...CTT--TTEEEEEEECE- CS
  Peptidase_S15  79 dsdeaedgadvidWlak...q.pwsnGkVgmtGiSYlGttqlla...aatgvpalkaivpeaai 135
                    + + +ed+++v++W++    + +  + +V   GiS +G+++ ++   a ++   lk ++p+++ 
     EEA21167.1 162 MGKNIEDAWAVLSWVRDssgKlNIIKSSVSLGGISAGGYLSCILqhlARDDNVPLKLVIPAVPP 225
                    67899***********9998669999*************9987522266677789999998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (365 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       295  (0.0164538); expected 358.6 (0.02)
Passed bias filter:                      281  (0.0156729); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2639.30
//
Query:       EEA21168.1  [L=917]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.9e-53  179.5   2.7    6.9e-53  179.5   2.7    2.4  3  Glyco_trans_2_3  Glycosyl transferase family group 2
     0.0087   15.9   0.0      0.022   14.6   0.0    1.6  1  Glycos_transf_2  Glycosyl transferase family 2


Domain annotation for each model (and alignments):
>> Glyco_trans_2_3  Glycosyl transferase family group 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   1.9       1.5   1.3e+04     168     193 ..     321     346 ..     290     348 .. 0.71
   2 !  179.5   2.7   7.7e-57   6.9e-53       1     196 [.     543     783 ..     543     784 .. 0.88
   3 ?   -6.5   5.2         2   1.8e+04     143     143 ..     852     852 ..     789     902 .. 0.47

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 1.5
  Glyco_trans_2_3 168 plhlallllfsllalalvllllllla 193
                      p + +++ll++l ++++++l++++++
       EEA21168.1 321 PMLPRIALLAPLPIFMFFTLFFTIVI 346
                      44446677888888888888888775 PP

  == domain 2  score: 179.5 bits;  conditional E-value: 7.7e-57
  Glyco_trans_2_3   1 iilllDaDtvlppdclreiaaela.spevaivqgpvlvmnv.anwleelaalffaedhgkdilvrealgrvvpsvGsgaflrrsalqevg.... 88 
                      iill+D+Dt++p dcl + a e++ spevai+q+ ++vm+v ++++e+ +++f++  ++ +i++++++g+++p+vG++aflr++a+q+v+    
       EEA21168.1 543 IILLIDCDTRVPIDCLSLGALEMEeSPEVAIIQHASGVMQViHSFFENAITYFTN-LVYLLIRFSVGNGDCAPFVGHNAFLRWKAIQSVSfmen 635
                      79**********************77*************7659999999998887.5666788889**************************** PP

  Glyco_trans_2_3  89 ....gwdgdessvsEDfdmglrlqrkGyrvrfvpes..lvkekspltlraalrQrkRwayGc..el.....eklil.................. 151
                          +w+  es+vsEDfdm+lrlq++G++vr++++    +ke+++lt  ++l +++++ayGc  ++     ++  +                  
       EEA21168.1 636 giekFWS--ESHVSEDFDMSLRLQTAGFVVRLATYDkgEFKEGVSLTAFDELLRWEKYAYGCseLIfhpvyQW--Iyrgpftelfrrflwsnmk 725
                      *******..***************************999***********************86225444422..1346666666677777777 PP

  Glyco_trans_2_3 152 ...lvrllgylgsllw..salplhlallllfslla........lalvlllllllaall 196
                         ++  lgy+g++ +  ++lpl++++++l++++a         ++ +l+ +l+++++
       EEA21168.1 726 vsaKFTILGYIGTYYAigASLPLSITNYFLTGWIAadldhsylPSWDMLCGTLFIFVF 783
                      77788889***999754488*************999******999999*****99987 PP

  == domain 3  score: -6.5 bits;  conditional E-value: 2
  Glyco_trans_2_3 143 G 143
                      G
       EEA21168.1 852 G 852
                      0 PP

>> Glycos_transf_2  Glycosyl transferase family 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   2.4e-06     0.022      80     168 ..     541     629 ..     538     631 .. 0.93

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 2.4e-06
                      SSEEEEEESSEEE-TTHHHHHHHHHHH.TTCEEEEEEEEEECCCCCCCHC-SSEEEECCHCCCCHCCCCCCSTTCSTCCCEEEEHHHHH CS
  Glycos_transf_2  80 gdyilflDaDdepdpdwleklvealekdgadvvlgqrprifgetdeiernkrvgenerlyfkerkrslkgnlsfeigsaallrrealee 168
                      g++il++D D+ ++ d+l+  + ++e+ ++ +++++     +  + +  n  +++ + +y  +r    +g+ + ++g++a lr +a+++
       EEA21168.1 541 GEIILLIDCDTRVPIDCLSLGALEMEESPEVAIIQHASGVMQVIHSFFENAITYFTNLVYLLIRFSVGNGDCAPFVGHNAFLRWKAIQS 629
                      89*************************99988888888999999999999888******************************999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (917 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       545  (0.0303977); expected 358.6 (0.02)
Passed bias filter:                      333  (0.0185733); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.72u 0.29s 00:00:01.01 Elapsed: 00:00:00.49
# Mc/sec: 5627.05
//
Query:       EEA21169.1  [L=334]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-77  260.8   1.2    1.4e-77  260.5   1.2    1.1  1  Glyco_hydro_cc  Glycosyl hydrolase catalytic core


Domain annotation for each model (and alignments):
>> Glyco_hydro_cc  Glycosyl hydrolase catalytic core
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  260.5   1.2   7.6e-82   1.4e-77       1     239 []      38     283 ..      38     283 .. 0.96

  Alignments for each domain:
  == domain 1  score: 260.5 bits;  conditional E-value: 7.6e-82
  Glyco_hydro_cc   1 Glayn..adasddkllsaksskisWyYnwsskpsselssaa...lefvPmlwgaksadtdalanvksa..akenskylLgFNePDlks...qsnm 85 
                     Gl+y+  +++sdd+++ a++s+++WyY++++ p + +s+ +   +efvPmlwg+ +++  + +++ks     +n++++L+FNePD +s   +s++
      EEA21169.1  38 GLVYIpsDHPSDDQIWVADNSDLTWYYDYKDIPAAAYSNRTqqeFEFVPMLWGSANSS-GFASEIKSQiaTGRNITHILTFNEPDGTSstgGSEI 131
                     7888888999***********************99988887899**********9998.8888888887779**************88899**** PP

  Glyco_hydro_cc  86 speeAaklwkqliqplrekgvklvsPavaatnseegleWldeFleacs...kdckvdflavHwYkgdfeelkehieelheayn.kpiWvTEfalq 176
                     sp++Aa+ w++ i+plr+++vk+++P+v  t+s++gl+Wl+eF+++c+   ++c+vdf+++HwY g+f++l+++++++ ++y+  +iW+TE+a  
      EEA21169.1 132 SPADAASIWIDDIEPLRNENVKIGAPSV--TGSQSGLTWLSEFFSNCTslkTNCTVDFIPLHWY-GNFQGLASYLGQVVATYPnTSIWITEYA-- 221
                     ****************************..999*****************99************.******************9*********.. PP

  Glyco_hydro_cc 177 sesgdasqeetkeflnevlawldsqeyVeryawfg.frsevsnvgannaLldenGeltelgsaY 239
                        + a+ ++t++f++++++++d+ +yVery++fg frs+ snvg+n ++l++nG+lt++gs+Y
      EEA21169.1 222 --LAHADLKDTQAFFQTSAEYFDRLDYVERYSYFGsFRSSISNVGPNATMLTQNGQLTDIGSWY 283
                     ..799**********************************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (334 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       589  (0.0328518); expected 358.6 (0.02)
Passed bias filter:                      442  (0.0246528); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.31s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 2203.88
//
Query:       EEA21170.1  [L=462]
Description: gram-negative bacteria binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.6e-17   61.3   0.5    1.5e-16   60.4   0.5    1.5  1  Glyco_hydro_16  Glycosyl hydrolases family 16


Domain annotation for each model (and alignments):
>> Glyco_hydro_16  Glycosyl hydrolases family 16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.4   0.5   8.1e-21   1.5e-16      22     141 ..     185     352 ..     164     390 .. 0.76

  Alignments for each domain:
  == domain 1  score: 60.4 bits;  conditional E-value: 8.1e-21
                     EEEEEEE..........................EEEEEEEE..CCEESSEEEEEEEE---STTEEEEEEEETGG.....TSTTEEEEE.EEETT- CS
  Glyco_hydro_16  22 ltltldk..........................esgsriks..kksflyGkvearikaaksaGvvtafylssed.....ekahdEiDi.EflGnd 82 
                      tl+l++                            ++r+++  k++++yGk+e+++k+++++ +++a++++ e+     ++ ++EiDi E  Gnd
      EEA21170.1 185 YTLNLTQqgvcttnnlvdcvrvsnistgaiinpVRSARLTTkgKHNITYGKIEVTAKLPRGDWLWPAIWMMPEEsvygeWPLSGEIDImESKGND 279
                     44444445566666666666666666677777666999999999**************************643335678***************9 PP

                     TTE.......EEEEEEBTTBSG.....E..EEEEETSS-TTTS-EEEEEEEETTEEEEEETTEEEEEEESSHH CS
  Glyco_hydro_16  83 tgk.......vqtnvygkGkgk.....r..ekrlslwfdptedfHtYaieWtpdkikfyVDgkpvrtltkkea 141
                      ++       v  ++++  +       r    ++++  d ++++HtY++eW++++i  +VD ++ + ++    
      EEA21170.1 280 GRTydggrnlVGGTLHWAPNPVldafyRtnGVKYTTRGDYSDNYHTYGMEWSDEYIYTWVDSRLAQSMYIPFG 352
                     9999999999999999877655445541568899999*************************99988776544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (462 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       387  (0.0215851); expected 358.6 (0.02)
Passed bias filter:                      301  (0.0167884); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 3226.51
//
Query:       EEA21171.1  [L=544]
Description: MFS alpha-glucoside transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.3e-60  202.9  21.0    1.1e-59  202.6  21.0    1.1  1  Sugar_tr  Sugar (and other) transporter
    1.6e-12   47.0  23.5    1.6e-12   47.0  23.5    2.1  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  202.6  21.0   1.2e-63   1.1e-59       5     452 .]      68     509 ..      64     509 .. 0.90

  Alignments for each domain:
  == domain 1  score: 202.6 bits;  conditional E-value: 1.2e-63
                 HHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH....HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS- CS
    Sugar_tr   5 aalggllfgYdtgvigafltllkfaknfglsksksskee.ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsv 102
                  +++ +++gYd+ +i +f+++++f+++fg  + +++ ++ s+ +++ + ++  vG+++G lf  ++ d+fG +++++++ + + + +++ ++a+   s+
  EEA21171.1  68 LSTSLIMEGYDVVMITSFYSQTQFQRRFGTHNPDTNAYTiSAEWQSGLSNSSTVGQLFGLLFNAYAQDKFGCRPTMMFFMAWMAVMIFIPFFAP---SL 163
                 455559****************************9999987788888999999*****************************************...** PP

                 TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHHT CS
    Sugar_tr 103 evlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPrylvek 201
                  vl++g   +G+++G++++l++ y+sE+ p+ lR +++ +  +++ +Gil+++++  ++  ++++ gwr+++++q+v+++  li+ +f+PESP+  v +
  EEA21171.1 164 SVLAFGEAMCGLSWGVFQTLSTGYASEVVPTVLRPYVTAYICMCWGAGILLSSGVVRAVTGIQGDLGWRLPFAIQWVWPVPPLIAAYFAPESPWNAVRR 262
                 *************************************************************************************************** PP

                 T-HHHHHHHHHHHHHC.....HHHHHHHHHHHHHHHHHHH......HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH..HHH CS
    Sugar_tr 202 gkeeeakevlaklrge.....edadrelaeekdsleaeqeee.kaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsks..llv 292
                 gk + a+++l +lr++     ++++  la + ++++ e+ee+  as  e ++ ++  +r+ i +v++++q l G nai+ ys t++e +g+s+   +  
  EEA21171.1 263 GKLDLARKSLMRLREDspqkeKEVEATLAYIRHTTQLEMEESgDASFFECFQGVN-WRRTEINCVVWAAQILYG-NAILGYSVTFLEAAGFSEIqaFDL 359
                 ************8887533334444444445555555555558777777888867.778888899999999999.******************99999* PP

                 HHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHT.TTTHHHHHHHHHHSHTTTHHHHHHH CS
    Sugar_tr 293 tiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfal.gwgpvpwvlvsElfpqsvRskalai 390
                 +i +++  ++  +++          t+++ G+++m++ +v +g   l ++++    s+vai +++++  l ++ ++gpv++ +v+E+ + ++R+k++ i
  EEA21171.1 360 NISLSTCYIIGGIIS----------TIYMGGLTFMFFRLVAIG--GLGFSHS--THSNVAIGGLLVVSTLCNMiTVGPVCYPIVAETPSGRLRYKTIVI 444
                 ***************..........99***************9..3333333..248999999888877666449************************ PP

                 HHHHHHHHHHHHHHHHHHHHCHHH...T-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 391 avavnwlanflisllfpiiteaig...ggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                   +v ++ +++ + ++p + +a+    g++ +l++ag ++l  i+++f +petk rt+ ei+ lf
  EEA21171.1 445 GRFVYNVTQIFSNSVTPRMIQASAwnwGAKAGLFYAGTNLLCNIWCWFRLPETKDRTFGEIDILF 509
                 **********************99999**********************************9876 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.0  23.5   1.8e-16   1.6e-12      12     320 ..      79     423 ..      62     456 .. 0.64
   2 !    2.7   7.2    0.0053        48      37     181 ..     363     501 ..     355     507 .. 0.80

  Alignments for each domain:
  == domain 1  score: 47.0 bits;  conditional E-value: 1.8e-16
       MFS_1  12 rsilgpalpl.alaedlg..........ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlga 99 
                   ++++++++   ++ +g          is+  ++ l    ++g++++ l+ ++  d+fG r+++++ ++++a+++++++fa+sl +l+++ +++Gl  
  EEA21171.1  79 VVMITSFYSQtQFQRRFGthnpdtnaytISAEWQSGLSNSSTVGQLFGLLFNAYAQDKFGCRPTMMFFMAWMAVMIFIPFFAPSLSVLAFGEAMCGLSW 177
                 444555555444444444433333322233333333666699*********************************99999977777************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg...Wravfyilaivsllafvlfllllpeepperkrkspkeee....... 188
                 g++ +++  ++++++p   r+ +++++ +++++G++l  ++  +++   g   Wr++f i  +  +  ++  ++++  e p ++  ++k ++       
  EEA21171.1 178 GVFQTLSTGYASEVVPTVLRPYVTAYICMCWGAGILLSSGVVRAVTGIQGdlgWRLPFAIQWVWPVPPLI--AAYFAPESPWNAVRRGKLDLarkslmr 274
                 **************************************999999996666788*************9966..377744444444444444446666777 PP

       MFS_1 189 ..............kgtgpaplvpawkallkdpvl..................w.......illialllfffgfsglltllplylqevlgls..gllla 246
                                          + ++++  +l                  w       ++++a +l   g++ +l ++ ++  e  g+s   ++ +
  EEA21171.1 275 lredspqkekeveaT----------LAYIRHTTQLemeesgdasffecfqgvnWrrteincVVWAAQILY--GNA-ILGYSVTF-LEAAGFSeiQAFDL 359
                 766643333333330..........344444443333333333333444444466556533344444444..555.55555554.89999997733555 PP

       MFS_1 247 glllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllllvlvliGfglgfvfps 320
                  + l+ ++++g   +++++ ++         l ++++ l+a  gl +   t+s+v++  +lv+ +++  +++++
  EEA21171.1 360 NISLSTCYIIG---GIISTIYMG-------GLTFMFFRLVAIGGLGFSHSTHSNVAIGGLLVVSTLCNMITVGP 423
                 54466666666...555555553.......34455555555555555555544555555555555544444333 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.0053
       MFS_1  37 lltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfasslwlllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGa 134
                 l t+y +g +++++ +G l+  f  r v + gl ++ ++ + +++   +   llv+  l+ + +  + p+++ ++a+  +++ r + i +    +++  
  EEA21171.1 363 LSTCYIIGGIISTIYMGGLTFMF-FRLVAIGGLGFSHSThSNVAI--GG---LLVVSTLCNMIT--VGPVCYPIVAETPSGRLRYKTIVIGRFVYNVTQ 453
                 67788888888888888886666.677777777777777555555..56...999999999996..********************************* PP

       MFS_1 135 ilgpllggllasslgWrav...fyilaivsllafvlfllllpeepperkr 181
                 i+   + + ++++  W +     ++ a+  ll+   ++++++ ++++ ++
  EEA21171.1 454 IFSNSVTPRMIQASAWNWGakaGLFYAGTNLLC--NIWCWFRLPETKDRT 501
                 ***********9999999867777888888888..445777777776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (544 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       476  (0.0265492); expected 358.6 (0.02)
Passed bias filter:                      287  (0.0160076); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 3598.27
//
Query:       EEA21172.1  [L=685]
Description: oxidoreductase, 2OG-Fe(II) oxygenase family, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.4e-34  119.4   0.1    8.3e-32  110.4   0.0    2.4  2  DIOX_N         non-haem dioxygenase in morphine synthesis N-t
    1.3e-12   48.1   0.0    3.2e-12   46.8   0.0    1.6  1  2OG-FeII_Oxy   2OG-Fe(II) oxygenase superfamily
    1.7e-11   45.2   0.0    3.7e-11   44.1   0.0    1.5  1  Abhydrolase_6  Alpha/beta hydrolase family
    4.2e-05   23.3   0.1    7.1e-05   22.6   0.1    1.3  1  Abhydrolase_1  alpha/beta hydrolase fold
     0.0002   20.7   0.0     0.0079   15.5   0.0    2.3  2  Hydrolase_4    Serine aminopeptidase, S33
     0.0015   18.4   0.1       0.21   11.4   0.0    2.8  3  Abhydrolase_2  Phospholipase/Carboxylesterase
     0.0024   17.8   0.0     0.0053   16.6   0.0    1.5  1  Lipase_3       Lipase (class 3)


Domain annotation for each model (and alignments):
>> DIOX_N  non-haem dioxygenase in morphine synthesis N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.4   0.0   3.2e-35   8.3e-32       1     117 [.     325     445 ..     325     446 .. 0.96
   2 !    6.5   0.0    0.0053        14      50      91 ..     484     522 ..     476     543 .. 0.74

  Alignments for each domain:
  == domain 1  score: 110.4 bits;  conditional E-value: 3.2e-35
      DIOX_N   1 iPvidlsplsddedraavaeqlreAcrevGffyvvnhgvpeelidelfeaareFFalPeeeKekl..akspsfrGysrlgeektdgkkldwkesfdlgt 97 
                 +P++d ++ +++++r+a++++l++A+ +vGffy++n+gvp++++++  e++  +F+lP+e+K+++   +s++f Gy rlg+e t+  k d++e+fd++t
  EEA21172.1 325 VPILDYAETASPSTRPAFLKALKAAIVNVGFFYLKNTGVPDKVLSDFTEQSIALFNLPLEKKLEIemVNSKHFLGYARLGQEVTAL-KNDYREQFDFAT 422
                 7******99999*****************************************************999999**************9.************ PP

      DIOX_N  98 elp...eddpagkplegpnqwPe 117
                 elp   +++p +++l+gpnqwP+
  EEA21172.1 423 ELPapgPQEPLYRNLRGPNQWPD 445
                 ***6666666************8 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0053
      DIOX_N  50 aareFFalPeeeKeklakspsfrGysrlgeektdgkkldwke 91 
                 a ++FF+ P++ K+kl k p+    ++  +e t+g ++  k+
  EEA21172.1 484 AFEQFFDHPQQNKLKLIKYPEPVDSKP--NEDTQG-VGPHKD 522
                 679*************77665555544..555555.555555 PP

>> 2OG-FeII_Oxy  2OG-Fe(II) oxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.8   0.0   1.2e-15   3.2e-12      13      98 ..     509     604 ..     493     606 .. 0.80

  Alignments for each domain:
  == domain 1  score: 46.8 bits;  conditional E-value: 1.2e-15
                   ---------EEEEEESSSEEEEEEE-.TT---EEEE.TEEEE----TTEEEEEE-HHHHHHTTS-S----EEE-.---GTGS........EEEEEEE CS
  2OG-FeII_Oxy  13 hpdpevilglgahtdaslltillqdd.vgglevfkd.gkwlrvppvdnslivniGdallflsngryksvlHrVl.pvneger........Rvsiayf 98 
                    p  + ++g+g+h+d  +lt+l+q +   glev+++ g+wl v+p +++l++niG al+ +++g  + + HrV+ + +  ++        R+s a f
    EEA21172.1 509 KPNED-TQGVGPHKDSCFLTFLMQGTpHTGLEVQNKaGTWLPVKPIPGTLVINIGRALEAITGGVCTATTHRVNlRMENYKDaqgnslgpRYSFAIF 604
                   23333.89*************999999******866477**********************************988777666677777778887766 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.1   0.0   1.4e-14   3.7e-11       1     208 [.      34     278 ..      34     286 .. 0.58

  Alignments for each domain:
  == domain 1  score: 44.1 bits;  conditional E-value: 1.4e-14
                    EEEE--GC.....G.C.HHHH...HHHHCCTCEEEEE--TTS.TS-GGCS--HHHCHHH....HHHHCCTT.........TTSEEEEEETCHHHHH CS
  Abhydrolase_6   1 vlllHGagssassW.l.vapL...aallaagvhvlapDlpGh.Grsdpppldledladl....aalldelaa.......gggpvvlvGHSlGGala 79 
                    v+l+HG+g++a  +   ++++      l+++v  l +++pG+ G     p++  ++ d      ++++ + +       g g +vl+GHSlGGa++
     EEA21172.1  34 VVLIHGSGATAAYFdNsAVSVaqsFHSLGHDV--LNISRPGYaG--NAIPTSEKPISDAipvfIDFIEQVYNekssakkGNGGIVLFGHSLGGAYS 125
                    8*********9999524344433333334446..9*******99..3333333333333311355555555588899999999***********99 PP

                    HHHHHCC........EE..EEES-........----TTTS----TTHHHHHHTT-C....CCCHCCHS-HSCCCCHHHCCCCHCHCCCGHHHHCCH CS
  Abhydrolase_6  80 laaapla......lvvg..vlldppp......talpagllaaalelllallallrl....lawlsreplprlfladedadaawrarlarlaallag 157
                    l+ a+ +      l  g   l ++p+      ++  +++++ ++ ++++ + + r+     +wl+ e+l ++++a++       +      + +++
     EEA21172.1 126 LLIAAEPqgrlplL--GvsTLGCAPVpngkilLSNHDPDPSNPRFIVETSPENIRKfmgeVEWLNIEALEPQLVAQVF-----EPGIKSEIREFSS 214
                    99555556788543..43466666554554443334444555555555555555555666788876656666666333.....3333222222222 PP

                    HC.....HTTCCHHTT-TTGCE.....EECTT-CHHHHCHHCCCH....STTEEETCE...SSS- CS
  Abhydrolase_6 158 lg.....llpaaawadlpvpll.....vlggeDplvprllerlla....qagarlpvvlpgaGHl 208
                    ++      + a +   lpv++l     +++++++  ++ +++l      ++ ++   +lp++GH 
     EEA21172.1 215 DEfydylVNKAYPAIKLPVQYLcaeaeIVWDNEKEARPIFDHLVSkftgAPEVDS-AILPRGGHN 278
                    2211111223556666666664444443488888888888888876655555555.999999994 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.6   0.1   2.8e-08   7.1e-05       1      94 [.      32     132 ..      32     137 .. 0.84

  Alignments for each domain:
  == domain 1  score: 22.6 bits;  conditional E-value: 2.8e-08
                    SEEEEE-STTTCGGGGTTGHHHHHHHHT..TSEEEEEEETTSTTSSSTTTGB......CHHSHHHHHHHHH.HHHHHCTTSSEEEEEETHHHHHHH CS
  Abhydrolase_1   1 pvlvilhGlpgssdvwaerglapaLakd..gfdvillDlrGvgySspapacin.....ddygtasvaddld.rildalgddkltlvGhSmGGmial 88 
                    p++v++hG ++++ ++ + ++  a +++  g+dv+ +  +G++    + ++ +     + + ++ ++ +++ +  ++ g++ ++l GhS+GG+ +l
     EEA21172.1  32 PLVVLIHGSGATAAYFDNSAVSVAQSFHslGHDVLNISRPGYAGNAIPTSEKPisdaiPVFIDF-IEQVYNeKSSAKKGNGGIVLFGHSLGGAYSL 126
                    78*************999777777777799***************9999988898766655553.444444677********************** PP

                    HHHHHH CS
  Abhydrolase_1  89 ayaaey 94 
                      aae 
     EEA21172.1 127 LIAAEP 132
                    **9985 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   3.1e-06    0.0079       6      99 ..      33     134 ..      28     148 .. 0.71
   2 ?    2.6   0.0     0.026        66     184     219 ..     223     259 ..     220     278 .. 0.82

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 3.1e-06
  Hydrolase_4   6 vvvlvHGlaehsgryae....laeaLaaqGfavyalDhrGhGrse...gkrghvpsfddyvdDlaafvekvkeehpel.....plfllGhSmGGlial 91 
                  +vvl+HG + ++  +++    +a+ +   G +v+ +   G+  ++         ++++d +  +  f+e+v +e++ +      ++l+GhS+GG+ +l
   EEA21172.1  33 LVVLIHGSGATAAYFDNsavsVAQSFHSLGHDVLNISRPGYAGNAiptS----EKPISDAIPVFIDFIEQVYNEKSSAkkgngGIVLFGHSLGGAYSL 126
                  7999999999999998744446788888899999999999988865543....3444444444444444444333333333349************** PP

  Hydrolase_4  92 lyllrypd 99 
                  l++++ + 
   EEA21172.1 127 LIAAEPQG 134
                  *9998876 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.026
  Hydrolase_4 184 eeraakitlPllllhGeaDkvvdpeas.relyerlgs 219
                  ++  ++i+lP++ l++ea+ v d+e+  r ++++l s
   EEA21172.1 223 NKAYPAIKLPVQYLCAEAEIVWDNEKEaRPIFDHLVS 259
                  677899******************9986556666554 PP

>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0     0.021        54      10      35 ..      27      52 ..      24      61 .. 0.75
   2 !   11.4   0.0   8.1e-05      0.21      77     146 ..      79     154 ..      72     162 .. 0.84
   3 ?   -1.1   0.0      0.53   1.4e+03      40      90 ..     163     212 ..     154     217 .. 0.83

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.021
                   SS---EEEEEE--TT--SHHHHHHHH CS
  Abhydrolase_2 10 kdkaqavviflHGlGdsghawaeaak 35
                   +d+a ++v+++HG G+++  + + a 
     EEA21172.1 27 QDRALPLVVLIHGSGATAAYFDNSAV 52
                   5678899**********976666555 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 8.1e-05
                    -B-HHHHHHHHHHHHHHHHHHHHTT....--GGGEEEEEETHHHHHHHHHHHT-SS..--SEEEEES---TTGGGT CS
  Abhydrolase_2  77 kedeagikksaekleelidaelkkg....ipssriiigGFSqGaalalylaltlpk..klggivafsgalplsqkl 146
                      +e+ i+++++ + ++i++  ++       +  i+++G S G+a +l  a   +   +l g+  +++a +++ k+
     EEA21172.1  79 PTSEKPISDAIPVFIDFIEQVYNEKssakKGNGGIVLFGHSLGGAYSLLIAAEPQGrlPLLGVSTLGCAPVPNGKI 154
                    5678899999999999999988777676688889*************9888876666699*********9998875 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 0.53
                    -TTEEEEEE---EEE-GGGTT-EEE-SS-B--SSTTS..-B-HHHHHHHHHHH CS
  Abhydrolase_2  40 lpnikfifphgpelpvtlnggmrmpaWfdlvglspek..kedeagikksaekl 90 
                      n+ fi+  +pe+  ++ g      W ++ +l+p+   +  e gik  ++++
     EEA21172.1 163 PSNPRFIVETSPENIRKFMGEV---EWLNIEALEPQLvaQVFEPGIKSEIREF 212
                    5689999999999999998888...8****99999987778888888877766 PP

>> Lipase_3  Lipase (class 3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   2.1e-06    0.0053      61     107 ..     107     149 ..      91     157 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 2.1e-06
                 HTT-EEEEEEEETHHHHHHHHHHHHHHHTT-SS---EEEEEES---- CS
    Lipase_3  61 kypeysivvtGHSLGgalAlLaaldlvengenekkkvtvvtfGqPrv 107
                 k+ +  iv+ GHSLGga +lL+a++ + +       ++v t+G++ v
  EEA21172.1 107 KKGNGGIVLFGHSLGGAYSLLIAAEPQGRL----PLLGVSTLGCAPV 149
                 4446789****************9877777....6677777777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (685 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       291  (0.0162307); expected 358.6 (0.02)
Passed bias filter:                      287  (0.0160076); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.61u 0.30s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 4552.23
//
Query:       EEA21173.1  [L=375]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.7e-16   59.5   0.0    7.6e-16   58.5   0.0    1.5  1  Gly_transf_sug  Glycosyltransferase sugar-binding region cont
  ------ inclusion threshold ------
      0.086   12.8   0.2       0.14   12.1   0.2    1.3  1  Ncstrn_small    Nicastrin small lobe
       0.29    9.6   0.3       0.41    9.1   0.3    1.1  1  Baculo_F        Baculovirus F protein


Domain annotation for each model (and alignments):
>> Gly_transf_sug  Glycosyltransferase sugar-binding region containing DXD motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.5   0.0   1.3e-19   7.6e-16       2      91 ..      86     166 ..      85     173 .. 0.93

  Alignments for each domain:
  == domain 1  score: 58.5 bits;  conditional E-value: 1.3e-19
  Gly_transf_sug   2 erekkaieslakahpdyqvvvlskelekvrvaildlefllsdtpwfeeakkllplfialsDllRlaiLykyGGiYlDtDvivlkslrnsi 91 
                     +++++  +s+++ +p +++ ++s   +         efl  +++wf+ +++++  ++++ D+l+++i+ +yGGiY+D+D  +l+sl +++
      EEA21173.1  86 AQWMRLRDSCINRNPGWEYKLWSSAES--------REFLQREYSWFLPIYDSYRHPVQRVDALKYFIMRHYGGIYIDMDNGCLESL-EPL 166
                     579999*****************9877........9999999*******************************************9.766 PP

>> Ncstrn_small  Nicastrin small lobe
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.2   2.4e-05      0.14     106     137 ..     280     310 ..     223     317 .. 0.68

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 2.4e-05
                   --SSTT---GGGSEESS-EEEE-HHH.HHHHH CS
  Ncstrn_small 106 yeWNpaGsgllfedfnfPiflleneteiekir 137
                     WN +G+gl +ed++f if    e+  ++ir
    EEA21173.1 280 VFWN-EGAGLTWEDWDFSIFHWIGENAAKVIR 310
                   5688.5**************988777666665 PP

>> Baculo_F  Baculovirus F protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.3   6.9e-05      0.41     554     598 ..     292     340 ..     279     350 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 6.9e-05
    Baculo_F 554 nwysnlvnw....wheikviviaivllllllvvlkiykccckgscsklk 598
                 +w   +++w      ++  i++a+ ++l ll +l + kccck+++ k++
  EEA21173.1 292 DWDFSIFHWigenAAKVIRITVAVTASLSLLTGLVVWKCCCKRRKAKSN 340
                 5655666777766889999999*********************998874 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (375 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       503  (0.0280551); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2675.32
//
Query:       EEA21174.1  [L=244]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.8e-35  120.7   0.0    1.6e-26   92.0   0.0    2.3  2  NTP_transf_9  Domain of unknown function (DUF427)


Domain annotation for each model (and alignments):
>> NTP_transf_9  Domain of unknown function (DUF427)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.6   0.0   2.2e-10     4e-06       1      74 [.      18      85 ..      18      98 .. 0.83
   2 !   92.0   0.0   8.8e-31   1.6e-26       1      92 [.     131     224 ..     131     225 .. 0.97

  Alignments for each domain:
  == domain 1  score: 26.6 bits;  conditional E-value: 2.2e-10
                  EEEE-SS-EEEEES--EEEEETTS--EEEB-GGGB-GGGEEEEEEEEEETTTEEEEEEEEEETTEEEEEEEEEE CS
  NTP_transf_9  1 vrvklngtvvaetddavvveetglppryYfppedvklellkpsdtttvCpwKGeasyyslavdgkevkdaaWsY 74
                  vrv +ng+ v++++ +++v+e+ + p+yYf  +++++e+l++++         +a  y+l+++gk+ + a+  +
    EEA21174.1 18 VRVLFNGQFVVDANVPKLVWEHPYFPVYYFQSSAIRPEYLTNKQP------GEDADTYDLTINGKTSPSAVKLF 85
                  6899***********************************998865......23677777777777777666655 PP

  == domain 2  score: 92.0 bits;  conditional E-value: 8.8e-31
                   EEEE-SS-EEEEES--EEEEETTS--EEEB-GGGB-GGGEEEE.EEEEEETTTEEEEEEEEEE.TTEEEEEEEEEESS--TT-GGGTT-BEE-T CS
  NTP_transf_9   1 vrvklngtvvaetddavvveetglppryYfppedvklellkps.dtttvCpwKGeasyyslav.dgkevkdaaWsYpeptpeaaeikgyvaFya 92 
                   v+++++g+ va t+++++++etglp+r+Y+p +dv+l+ll++  ++t++Cp+KG+asyy ++  +g++ +  aW+Y++p+ e+a i+g++aFy+
    EEA21174.1 131 VQIEIDGVEVASTSRPKLLYETGLPVRIYIPHTDVRLDLLEDDvERTSHCPYKGDASYYVVNLpNGDRKPGLAWWYKTPKIESAGIEGHIAFYD 224
                   6899**************************************99*****************9978889*************************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (244 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       373  (0.0208043); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 1649.09
//
Query:       EEA21175.1  [L=196]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.7e-21   74.2   0.2      8e-12   44.9   0.0    2.4  2  NTP_transf_9  Domain of unknown function (DUF427)


Domain annotation for each model (and alignments):
>> NTP_transf_9  Domain of unknown function (DUF427)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.2   0.0   1.4e-10   2.6e-06       1      74 [.      18      85 ..      18      98 .. 0.83
   2 !   44.9   0.0   4.5e-16     8e-12       1      53 [.     131     184 ..     131     191 .. 0.95

  Alignments for each domain:
  == domain 1  score: 27.2 bits;  conditional E-value: 1.4e-10
                  EEEE-SS-EEEEES--EEEEETTS--EEEB-GGGB-GGGEEEEEEEEEETTTEEEEEEEEEETTEEEEEEEEEE CS
  NTP_transf_9  1 vrvklngtvvaetddavvveetglppryYfppedvklellkpsdtttvCpwKGeasyyslavdgkevkdaaWsY 74
                  vrv +ng+ v++++ +++v+e+ + p+yYf  +++++e+l++++         +a  y+l+++gk+ + a+  +
    EEA21175.1 18 VRVLFNGQFVVDANVPKLVWEHPYFPVYYFQSSAIRPEYLTNKQP------GEDADTYDLTINGKTSPSAVKLF 85
                  6899***********************************998865......23677777777777777776655 PP

  == domain 2  score: 44.9 bits;  conditional E-value: 4.5e-16
                   EEEE-SS-EEEEES--EEEEETTS--EEEB-GGGB-GGGEEEE.EEEEEETTTE CS
  NTP_transf_9   1 vrvklngtvvaetddavvveetglppryYfppedvklellkps.dtttvCpwKG 53 
                   v+++++g+ va t+++++++etglp+r+Y+p +dv+l+ll++  ++t++Cp+K 
    EEA21175.1 131 VQIEIDGVEVASTSRPKLLYETGLPVRIYIPHTDVRLDLLEDDvERTSHCPYKV 184
                   6899**************************************99********95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (196 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       486  (0.0271069); expected 358.6 (0.02)
Passed bias filter:                      386  (0.0215294); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.24s 00:00:00.64 Elapsed: 00:00:00.39
# Mc/sec: 1505.39
//
Query:       EEA21176.1  [L=295]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.8e-18   64.9  14.6    2.1e-17   63.2  14.6    1.7  1  UbiA      UbiA prenyltransferase family


Domain annotation for each model (and alignments):
>> UbiA  UbiA prenyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.2  14.6   1.2e-21   2.1e-17      20     245 ..      54     275 ..      34     285 .. 0.73

  Alignments for each domain:
  == domain 1  score: 63.2 bits;  conditional E-value: 1.2e-21
        UbiA  20 llllllllgtllaaaaanalNdyfDreiDadmertpnRPlvsGrispkealifaivllilgllll.alllnpltallgllalllyvvYtglrlKrrtll 117
                   ++ +ll +ll+  +  + N++  +e+D++  ++p+RP+++G+ + k+a+i ++vl +l ++ + +l+++ ++a+++++++    + + l ++++++ 
  EEA21176.1  54 IAIAKTLLLGLLYLYSFVVGNQICGVEEDQI--NKPDRPIAAGATTLKAARIRWAVLTMLYFSYGcYLGVGVWSAMWIAISV----AHNFLSFGDFGPT 146
                 34455677777888888888***********..****************************997756666666666666666....55535799***** PP

        UbiA 118 gtvvggiafglppllgwaavtgslsllalllalavflltwaialandlrdregDrkagiktlpvvlGrkaaril..lalllavllla.....lllllla 209
                 +++++g+ ++  ++++w + +    + + ++ ++ +   ++i l  dlrd+ gD+++g++t+p+++G+   ri+  l    +  +++      + +l +
  EEA21176.1 147 KDMCIGLGCVAQLTAAWLIGGAPYEVGWNWIKIIALYTLFPIPLQ-DLRDVPGDLAVGRRTTPILMGDMPCRIYisL---GV--FISqflliKYRILDY 239
                 *******************77777666666666645566666665.**************************95432...22..222224333445555 PP

        UbiA 210 lllllylllalllaalallraarlvrrrdakkaakf 245
                  + + +++l+++l+ lal + +rl++ rd k+++ +
  EEA21176.1 240 RVDWSTVALSTILGFLALTVIFRLFAFRDVKSDRYS 275
                 666777777777777777777788877777776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (295 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       468  (0.026103); expected 358.6 (0.02)
Passed bias filter:                      251  (0.0139997); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2211.25
//
Query:       EEA21177.1  [L=704]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-07   31.3  11.4    2.9e-07   30.5  11.4    1.4  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.5  11.4   1.6e-11   2.9e-07       1      38 [.      40      76 ..      40      78 .. 0.91

  Alignments for each domain:
  == domain 1  score: 30.5 bits;  conditional E-value: 1.6e-11
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfysessk 38
                +aC++C k+K+KC + +P C+nC +++l C++++e   
  EEA21177.1 40 RACNECQKRKIKCIGSNP-CKNCHENSLYCEINDETDG 76
                69****************.************8887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (704 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       527  (0.0293937); expected 358.6 (0.02)
Passed bias filter:                      361  (0.020135); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.24s 00:00:00.86 Elapsed: 00:00:00.40
# Mc/sec: 5225.11
//
Query:       EEA21178.1  [L=387]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    9.8e-46  155.1   3.1    1.1e-25   90.3   0.2    2.2  2  Fasciclin  Fasciclin domain


Domain annotation for each model (and alignments):
>> Fasciclin  Fasciclin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.4   0.3   3.2e-22   5.8e-18       2     126 ..      30     169 ..      29     172 .. 0.85
   2 !   90.3   0.2   6.1e-30   1.1e-25       3     128 .]     184     301 ..     182     301 .. 0.94

  Alignments for each domain:
  == domain 1  score: 65.4 bits;  conditional E-value: 3.2e-22
                 GGHHHHHHHHTT.TCCCCCTCSSSSEEEEEE-HHHHCCCHHHHHHHHHT....CHHHHHHHHHTTEEESSS-HHHHHHH.........HEEEEC.CTTS CS
   Fasciclin   2 dlstfvslleka.glaeeLnkkdgglTvFaPtneAfaklppellaklln....dkkklkeiLkyHvvpetvsssalkka.........setlat.lleg 85 
                 +ls +++ll++  ++++ L  + +++T+++P+n+A+a++ +++  ++l+    +++  +++L yH++++++++s++ ++         + t  t + +g
  EEA21178.1  30 QLSSLSALLSSYpRIESSL-ANISNVTILVPSNAALANFTNSTSFQVLAsgpsGNRTIEDLLSYHILQGEYYASNITDTpafihtylnD-TAYTnVTSG 126
                 6899999999999999***.6669***************77777777767999**************************8888888844.444436667 PP

                 SEEEEEEEGGTTEEEETT...EEEEEEEEEEESSEEEEEESS-T CS
   Fasciclin  86 aklrvniekgngtvtvng...karvvrsdieatngvihvidkvL 126
                 + ++  ++ +n+t++  g   +++v+++d + t gv+h+idkvL
  EEA21178.1 127 QIVEAIKQ-DNETYFYSGllaNSTVTQADLNFTGGVVHIIDKVL 169
                 77766666.678899999*************************9 PP

  == domain 2  score: 90.3 bits;  conditional E-value: 6.1e-30
                 GHHHHHHHHTTTCCCCCTCSSSSEEEEEE-HHHHCCCHHHHHHHHHTCHHHHHHHHHTTEEESSS.-HHHHHHHHEEEECCTTSSEEEEEEEGGTTEEE CS
   Fasciclin   3 lstfvsllekaglaeeLnkkdgglTvFaPtneAfaklppellakllndkkklkeiLkyHvvpetv.sssalkkasetlatllegaklrvniekgngtvt 100
                 ls +v +l++ +l+++  ++ ++ T+FaP+n+Af++++++l ++   +  +l++iL++Hv+++t+ +s +lk+  +++   ++g +l+v+ie  ng+++
  EEA21178.1 184 LSAVVGALQAEKLTQTV-DELKNATIFAPENSAFQAIGSALGNF---TTGQLTAILECHVLNGTLaYSTDLKND-TQYIA-VDGRNLTVRIE--NGSIF 274
                 788999***********.7879***************9999999...79**************776*******8.88887.9**********..***** PP

                 ETTEEEEEEEEEEESSEEEEEESS-TSX CS
   Fasciclin 101 vngkarvvrsdieatngvihvidkvLlp 128
                 v++ arvv+++   +ngv+hvid+vL p
  EEA21178.1 275 VDS-ARVVTPNLLVANGVVHVIDNVLNP 301
                 ***.**********************87 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (387 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       780  (0.0435049); expected 358.6 (0.02)
Passed bias filter:                      419  (0.02337); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 2455.38
//
Query:       EEA21179.1  [L=82]
Description: hypothetical protein PMAA_049770 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (82 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1412  (0.0787551); expected 358.6 (0.02)
Passed bias filter:                      569  (0.0317363); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.44
# Mc/sec: 556.85
//
Query:       EEA21180.1  [L=159]
Description: hypothetical protein PMAA_049780 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (159 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       433  (0.0241508); expected 358.6 (0.02)
Passed bias filter:                      361  (0.020135); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.28s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 1123.86
//
Query:       EEA21181.1  [L=690]
Description: proteinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      5e-24   84.4   0.0    1.8e-23   82.6   0.0    1.9  2  Abhydrolase_4  TAP-like protein
      2e-15   57.2   0.0    4.1e-11   43.0   0.0    2.9  2  Abhydrolase_1  alpha/beta hydrolase fold


Domain annotation for each model (and alignments):
>> Abhydrolase_4  TAP-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       0.5   4.5e+03      41      57 ..     298     314 ..     286     318 .. 0.84
   2 !   82.6   0.0     2e-27   1.8e-23       3     103 .]     542     643 ..     540     643 .. 0.95

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 0.5
  Abhydrolase_4  41 qnerDpaTPyegakkla 57 
                    q+e D aT+y+  +k+a
     EEA21181.1 298 QQEEDKATGYHAEQKIA 314
                    7899******9988876 PP

  == domain 2  score: 82.6 bits;  conditional E-value: 2e-27
  Abhydrolase_4   3 vfgaalaesllsCagwpvspqrprdestakga.apvLllqnerDpaTPyegakklakalggavlvtvegeGHgalaagntCvdkavdaYLltGelp 97 
                     +g+++a+  l+C gw+ + ++ ++   a ++ +p +l++++ Dp+TP+++akk++++++g+ ++ + +eGH++ ++++ C  ka+++Y++tG+lp
     EEA21181.1 542 SIGDYWASVYLTCVGWQPRAKWRVNGPYAGNTsHPLMLVSTTLDPVTPLKSAKKMSSRFNGSIVLEQSSEGHTTGSGPSVCSAKAIRKYFQTGQLP 637
                    689*******************99999985544*****************************************99******************** PP

  Abhydrolase_4  98 addtvC 103
                    +++t C
     EEA21181.1 638 ETGTLC 643
                    ****99 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.0   0.0   4.6e-15   4.1e-11       1     110 [.     142     361 ..     142     365 .. 0.90
   2 !   10.1   0.0   4.9e-05      0.44     185     251 ..     554     614 ..     516     616 .. 0.88

  Alignments for each domain:
  == domain 1  score: 43.0 bits;  conditional E-value: 4.6e-15
                    SEEEEE-STTTCGGGGTTGHHHHHHHHT..................TSEEEEEEETTSTTSSSTTTGB......CHH................... CS
  Abhydrolase_1   1 pvlvilhGlpgssdvwaerglapaLakd..................gfdvillDlrGvgySspapacin.....ddy................... 54 
                    ++++i++G+pg+s+v  ++  +++L+                     fd+i++D+rGv  ++p  +c +     +++                   
     EEA21181.1 142 GAVLINPGGPGGSGVAQALTTGRNLQTIvdadidflteshkhndsfYFDIIGFDPRGVNNTTPQFSCFPsllskVNFglqaeadgilgssadslmr 237
                    58*************77777777777777777888888999999***********************9888887555888888999999999999* PP

                    ..................................................................SHHHHHHHHHHH..HHHCTTSSEEEEEETH CS
  Abhydrolase_1  55 ..................................................................gtasvaddldri..ldalgddkltlvGhSm 82 
                                                                                       t  +a+   ++  +   g++kl ++G S+
     EEA21181.1 238 nwqrgaalsqscsevllardgndstgevlgehlntvpvardmleiierhaewrekqglkrqqeedkATGYHAEQKIAVrtRWDRGQEKLLYWGRSY 333
                    ******************************************************************777677665555449999************ PP

                    HHHHHHHHHHHHGGGEEEEEEESECSSC CS
  Abhydrolase_1  83 GGmialayaaeyperVkalvllgaidpa 110
                    G+ +++++a ++p+r++++ l+g +d+ 
     EEA21181.1 334 GTVLGATFATMFPDRISRMLLDGVVDTD 361
                    ***********************96654 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 4.9e-05
                    HHHHHHHHHHCCHHHHHHHHHCTHHHHSEEEEEEETTCSSSCHHHHHHHHHCHTSEEEEEEETCSSS CS
  Abhydrolase_1 185 alksieqwpttdsaklllrlrelknvlaptlvisgtsDplvppkaledlaqllpkkrlvvisdagHl 251
                     +++  +++++ ++++ ++         p +++s+t Dp++p k+  ++ + ++++ ++  s +gH+
     EEA21181.1 554 CVGWQPRAKWRVNGPYAGNTSH------PLMLVSTTLDPVTPLKSAKKMSSRFNGSIVLEQSSEGHT 614
                    5567777777777777888777......***************************999999999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (690 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       317  (0.0176809); expected 358.6 (0.02)
Passed bias filter:                      299  (0.0166769); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.24s 00:00:00.84 Elapsed: 00:00:00.41
# Mc/sec: 5034.78
//
Query:       EEA21182.1  [L=397]
Description: monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.3e-24   86.3   0.4    1.8e-17   63.7   0.1    2.7  2  FAD_binding_3  FAD binding domain
    4.3e-05   22.7   0.1    9.6e-05   21.6   0.1    1.6  2  Lycopene_cycl  Lycopene cyclase protein
    0.00026   20.3   0.4     0.0015   17.8   0.1    1.9  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    0.00028   21.1   0.1    0.00061   20.0   0.1    1.6  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
    0.00079   18.8   0.0     0.0013   18.0   0.0    1.3  1  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
     0.0017   17.5   0.1     0.0028   16.8   0.1    1.3  1  FAD_binding_2  FAD binding domain
  ------ inclusion threshold ------
      0.013   16.0   0.1      0.065   13.8   0.0    2.2  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
       0.03   13.9   0.0       0.05   13.2   0.0    1.4  1  DAO            FAD dependent oxidoreductase
       0.11   11.7   0.0       0.18   11.0   0.0    1.2  1  Thi4           Thi4 family


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.0   2.2e-07   0.00044       3      36 ..       7      40 ..       5      48 .. 0.92
   2 !   63.7   0.1   8.9e-21   1.8e-17     114     345 ..     116     365 ..     107     368 .. 0.72

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 2.2e-07
                   EEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSS CS
  FAD_binding_3  3 dVlIVGaGpaGlmlallLseaGvrvvlvekrstt 36
                    V+IVGaG+aGl la+ L++  +  v+v++ +t 
     EEA21182.1  7 RVIIVGAGLAGLALAHGLQKLNIAFVIVDRETTP 40
                   79****************************9875 PP

  == domain 2  score: 63.7 bits;  conditional E-value: 8.9e-21
                    HHHHHTEEETCSEEEECCE..ECCCCCCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHHHTGGEEEEEEEEEEEEEEEEEEC..-SCCCTTC... CS
  FAD_binding_3 114 haeerglqvrfktevesle..qdeegvtaevrdketgeeetvrakYlvGaDGgrStvrktlgiefegeetvyeagvldvlfda..dlsdivep... 202
                    h  ++gl+v+ +++++ ++   d+++v+a + d ++++  t+    +vGaDGg S+vr+ l    e+ ++v + ++++  f    d +++ e    
     EEA21182.1 116 HHLSQGLSVQYGKRLVDITvgPDDDEVAAHFDDGTQETG-TI----IVGADGGISQVRRWLLG-NEAAQEVLPCQFMNFSFGLpaDSAQWLERslg 205
                    556788888888887654422799999999998864444.55....9************8864.58888899999999999764477777777888 PP

                    ..CEEEEECCTTEE.........EEEECCETEEEEEEEEECCE-GGGSCCCHHHHHHHHHHHHHHTTSSCEEEE......EEEEEEEEEEEEESSS CS
  FAD_binding_3 203 ..lvlilsaesrgv.........mviPlentlerfyvqvearaekeersekfteeevkarlreivgektldvei......eevsawtvaqrvaeky 281
                      +++  ++ +  +         +  P    l  ++ +++++++ +++    + +e++ r++   ++ ++ ve+       +  ++++++    + 
     EEA21182.1 206 ptIEVAAHPRDMYMgislldkpdTKKPETW-LFYILAVWKLGDTSDGQGSGSQLSELRSRMDDWADPFKTVVEMlpddtfIKQDKLRIWHTKPWNN 300
                    753333333333336676644444444433.33334455566677777888888888888888777766666651111114555666666667778 PP

                    EETTEEE-GGGTEEE-STTSHHHHHHHHHHHHHHHHHHHHHTTSS-.GGGGHHHHHHHHHHHHHH CS
  FAD_binding_3 282 rkgrvflaGDAaHihpPtgGqGlNtaiqDavnLawkLaavlkGeAk.eelLdtYeeerravaqav 345
                    ++grv l+GDAaH ++   GqG N+ai+Da++L+ kL +v ++e + +e +dtY++ ++ ++++v
     EEA21182.1 301 HQGRVTLIGDAAHSMTFHRGQGGNLAIKDAYELFNKLVLVHREENDqKEAIDTYDKGALLRGEEV 365
                    99****************************************98762589*****9988887765 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.6   0.1   4.8e-08   9.6e-05       2      47 ..       8      48 ..       7      63 .. 0.84
   2 ?   -3.4   0.0       1.9   3.8e+03     156     179 ..     361     380 ..     358     387 .. 0.75

  Alignments for each domain:
  == domain 1  score: 21.6 bits;  conditional E-value: 4.8e-08
  Lycopene_cycl  2 vvviGaGpAglslAarlteakpglkvvlieaspsllfpnnyvWsde 47
                   v+++GaG+Agl+lA+ l  +k +++ v+++       p ++ W+  
     EEA21182.1  8 VIIVGAGLAGLALAHGL--QKLNIAFVIVDRE---TTPRDRNWCIT 48
                   89***************..**********543...34678889865 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 1.9
  Lycopene_cycl 156 yGvevevdnppfdldkmvlMDfrv 179
                    +G eve++++     +m +MD+ +
     EEA21182.1 361 RGEEVEISRQ----CTMAFMDYEN 380
                    5777777777....7999***974 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.1   7.5e-07    0.0015       2      36 ..       7      40 ..       6      53 .. 0.87
   2 ?   -0.3   0.0      0.26   5.1e+02     190     234 ..     114     160 ..      96     169 .. 0.77

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 7.5e-07
                 SEEEE--SHHHHHHHHHHHHHTS-EEEEETTHCHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  2 dvvviGgGpAGlaaaltlaqagakvtlvelegtcl 36
                 +v+++G+G AGla+a+ l++ ++  ++v +++t++
   EEA21182.1  7 RVIIVGAGLAGLALAHGLQKLNIAFVIV-DRETTP 40
                 8***************************.666665 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.26
                  HHHHHHTTEEEEESCEEEEEEETTE..EEEEEETTSCEEEESEEEE- CS
                  xxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 190 eealekeGvevklgtsvkeidgnge..klevvledgeeidadlvvva 234
                  ++++  +G  v+ g++ ++i+  ++  ++  + +dg+++    +v a
   EEA21182.1 114 TKHHLSQGLSVQYGKRLVDITVGPDddEVAAHFDDGTQETGTIIVGA 160
                  56777889999999999999988885566699999998666655555 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   0.1   3.1e-07   0.00061       1      28 [.      10      37 ..      10      40 .. 0.93

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 3.1e-07
                   EE--SHHHHHHHHHHHCCTEEEEEE-SS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekr 28
                   IvGaGl+Gl++A+ L+k ++  +++++ 
     EEA21182.1 10 IVGAGLAGLALAHGLQKLNIAFVIVDRE 37
                   9***********************9986 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   6.7e-07    0.0013       1      31 [.       9      38 ..       9      49 .. 0.93

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 6.7e-07
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEkgn 31
                 iI+GaG aGla a+ l+k+++  ++i+++++
   EEA21182.1  9 IIVGAGLAGLALAHGLQKLNI-AFVIVDRET 38
                 8********************.8*****975 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.1   1.4e-06    0.0028       2      31 ..       8      37 ..       7      43 .. 0.91

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 1.4e-06
                   EEEE--SHHHHHHHHHHHHTTT-EEEEESS CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGlkvavveke 31
                   vi++G+GlAGLa A+ +++ +   ++v+ e
     EEA21182.1  8 VIIVGAGLAGLALAHGLQKLNIAFVIVDRE 37
                   9******************99999999876 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   3.3e-05     0.065       1      35 [.       7      41 ..       7      47 .. 0.93
   2 ?   -2.1   0.0       2.9   5.8e+03      47      71 ..     114     138 ..     108     147 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 3.3e-05
                EEEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSS CS
   Pyr_redox  1 kvvvvGgGyiglElAgalaelgkkVtvversdkll 35
                +v++vG+G+ gl lA  l++l+    +v+r+ +++
  EEA21182.1  7 RVIIVGAGLAGLALAHGLQKLNIAFVIVDRETTPR 41
                79****************************99887 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 2.9
                 HHHHHHTTEEEECSEEEEEEEEETT CS
   Pyr_redox  47 qeklekngievllntkveeiegsed 71 
                 ++++  +g  v ++++++ i+  +d
  EEA21182.1 114 TKHHLSQGLSVQYGKRLVDITVGPD 138
                 5677788999999999999995554 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   2.5e-05      0.05       1      30 [.       7      38 ..       7      96 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 2.5e-05
                EEEEECTSHHHHHHHHHHHHTT..EEEEESSS CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..Vtllekgd 30
                +v+i+G+G +Gl+ A+ L++ +   ++++++ 
  EEA21182.1  7 RVIIVGAGLAGLALAHGLQKLNiaFVIVDRET 38
                59****************88788988999884 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0     9e-05      0.18      19      60 ..       7      47 ..       3      63 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 9e-05
                EEEEE--SHHHHHHHHHHHHCTTS-EEEEESSSS--TTTTTT CS
        Thi4 19 DvvivGaGssGLtaayylakkpdlkvailersvspGGGawlG 60
                 v+ivGaG +GL+ a+ l k  ++  +i++r+ +p    w  
  EEA21182.1  7 RVIIVGAGLAGLALAHGLQKL-NIAFVIVDRETTPRDRNWCI 47
                69*****************99.9******9998887777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       481  (0.026828); expected 358.6 (0.02)
Passed bias filter:                      460  (0.0256568); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.57u 0.25s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 2696.03
//
Query:       EEA21183.1  [L=486]
Description: hypothetical protein PMAA_049810 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.022   14.6   0.0      0.053   13.3   0.0    1.6  1  Rop-like  Rop-like
       0.36   10.1   3.2       0.54    9.6   3.2    1.2  1  TM231     Transmembrane protein 231


Domain annotation for each model (and alignments):
>> Rop-like  Rop-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   5.9e-06     0.053      26      44 ..     161     179 ..     144     183 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 5.9e-06
                 HHHHHTTTTGGGHHHHHHH CS
    Rop-like  26 DLaEdLPtnyeeipevAqk 44 
                 DLaE L t++e+ip++A++
  EEA21183.1 161 DLAETLLTGWENIPTTATR 179
                 ****************985 PP

>> TM231  Transmembrane protein 231
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   3.2     6e-05      0.54     244     294 ..     308     359 ..     275     365 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 6e-05
       TM231 244 tievelryp.eeeilYkpgfwellkwaWiqYlsilliflylfekikdflFqn 294
                 +i++e+++   ++ +Y p   +++++ Wi + ++ ++ l+++++   +l ++
  EEA21183.1 308 QITAEIQIInGKVTIYSPHWVNRMRNNWIVFWACIILQLWIITWPIIWLLEK 359
                 577888877456667**************************99877777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (486 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       553  (0.0308439); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.31s 00:00:00.89 Elapsed: 00:00:00.51
# Mc/sec: 2841.75
//
Query:       EEA21184.1  [L=190]
Description: carboxyvinyl-carboxyphosphonate phosphorylmutase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.6e-17   63.7   0.4    1.9e-17   63.5   0.4    1.0  1  PEP_mutase  Phosphoenolpyruvate phosphomutase
    5.8e-07   28.4   0.1      7e-07   28.1   0.1    1.1  1  ICL         Isocitrate lyase family


Domain annotation for each model (and alignments):
>> PEP_mutase  Phosphoenolpyruvate phosphomutase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.5   0.4   2.1e-21   1.9e-17      46     149 ..       7     115 ..       1     130 [. 0.86

  Alignments for each domain:
  == domain 1  score: 63.5 bits;  conditional E-value: 2.1e-21
  PEP_mutase  46 vpDgeelpleellaavraiaevvslPlivDledGygespeevaetvrrliaaGvvgvniEDk....kknd.aerqlldieefaekiaaaraaaeeag.f 138
                 +p +  + ++e+++ ++++a++v++ +++D ++Gy  s  +v++tv+++++ G + v+iED+    +++  +++ + + e++ ++i+aa +a ++++ +
  EEA21184.1   7 LPNTGYIAMQEMCEKIQEMARQVNISILADDDTGYD-STVNVRRTVESFAKSGPARVIIEDQawpkRCGHiKGKSAGSREDAYARIQAAHDARDQSQdI 104
                 67888899***************************5.599**********************997544454777777***************999999* PP

  PEP_mutase 139 vinARtdalll 149
                 +i AR+da++ 
  EEA21184.1 105 FILARIDAIFV 115
                 ********874 PP

>> ICL  Isocitrate lyase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.1   0.1   7.8e-11     7e-07     151     234 ..      32     113 ..      14     134 .. 0.84

  Alignments for each domain:
  == domain 1  score: 28.1 bits;  conditional E-value: 7.8e-11
                 -EEEE-TT-SSSHHHHHHHHHHHHHTT-SEEEE-SB-TT---------EEE--HHHHHHHHHHHHHHHHHTT---EEEEE--GG CS
         ICL 151 piiadadtGhGGltavvkltklfierGaaGihiedqasgtkkcGhmaGkvlvpiqehinrlvairaqadilgsdllvvartdse 234
                  i+ad dtG+  +  v + +  f + G a + iedqa   k+cGh+ Gk   + ++   r+ a+  + d    d++++ar d+ 
  EEA21184.1  32 SILADDDTGYDSTVNVRRTVESFAKSGPARVIIEDQAW-PKRCGHIKGKSAGSREDAYARIQAAHDARDQ-SQDIFILARIDAI 113
                 699*********************************96.69**********9999999999999888884.7899999999985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (190 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       633  (0.0353059); expected 358.6 (0.02)
Passed bias filter:                      523  (0.0291706); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1381.78
//
Query:       EEA21185.1  [L=555]
Description: general amino acid permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   4.2e-105  352.1  41.4   4.8e-105  351.9  41.4    1.0  1  AA_permease    Amino acid permease
    3.8e-21   75.4  46.8    5.1e-21   75.0  46.8    1.2  1  AA_permease_2  Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  351.9  41.4  5.3e-109  4.8e-105       2     476 ..      43     506 ..      42     509 .. 0.98

  Alignments for each domain:
  == domain 1  score: 351.9 bits;  conditional E-value: 5.3e-109
  AA_permease   2 vlvialggviGtglfvglgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgpelGfviGlnylfswitvlaleltaasi 99 
                  +++ia+gg iGt++fv++g +l+++Gp+g+llay l   vi+lv +s++e+a+++p++++f   as  +++++Gf+ G+n+++++++ +++e+ a++ 
   EEA21185.1  43 IQMIAIGGSIGTAMFVSIGGALNTGGPAGLLLAYGLYSCVIALVNNSMAEMAIYMPVNASFIRHASVWVDDAWGFMAGWNFFLYEAILIPFEISALNL 140
                  79************************************************************************************************ PP

  AA_permease 100 liqfwelvtdlpkawvtgavflvvlliinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkga.gfrflgdngsifknnlppgfakeeeg 196
                  +i fw   +++p   ++ a  +v + iinl++v++ygeaef+l++ ki+ + +++ +++i+++gg+p+++a gfr+++++g  f+++l++g    + g
   EEA21185.1 141 VIRFW--SDSVP-VGAICAACIVTYGIINLAAVRWYGEAEFWLSWGKILLMGIVFSFTFITMVGGNPKHDAyGFRYWNNPGP-FAEYLSGG----AMG 230
                  *****..*****.999999***************************************************************.999***99....999 PP

  AA_permease 197 afknfisvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasa...aspfvifikesgvsvlapl 291
                  + k+f+s++ +++fa+ G e+ a++agE+k P+ ++++a++ v ir ++f+++++l++g+++p+nd +l++   s+   asp+vi+++++gv++l++l
   EEA21185.1 231 RWKGFLSALWAASFAIVGPEYMAMVAGEAKLPRITVKRAFKAVYIRFGVFFIGGALCVGIVLPYNDQTLIANQGSGtgaASPYVIAMQNLGVNGLPHL 328
                  9**********************************************************************88888********************** PP

  AA_permease 292 inaviltaalssansslysasRvlyslakdglaPkvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliilsylr 389
                  +na++ t+++s++ +++y+asR+l+ la dg+aP++lkk++k+gvP+  ++++m++ +l+ll  s  +   +v  +l++i+++ g+i +++i+++y+ 
   EEA21185.1 329 VNALLVTSIYSAGDAYVYCASRTLHGLASDGHAPAFLKKCTKKGVPIYCLMITMLFPFLSLLQLSNGA--YVVLSWLVNIVTAGGIIDYIIICVNYIF 424
                  *************************************************************6655555..5*************************** PP

  AA_permease 390 fRkalkyqgrsieelgfkaallplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfliilvgvklhvknkrpq 476
                  f +a k+qg + +e+++ a l+p+ ++++l + i +++ ++++ +++     ++++ +sf+  y +v+  +i+++ +k+++++k+ +
   EEA21185.1 425 FWRACKAQGVNRREFSYYAYLQPWSTVFALCFEICVVVCYGYVNFMP-----GSFDISSFFTHYAMVFAAIILFFFWKIYKRTKFVK 506
                  ***********************************************.....999***************************99865 PP

>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.0  46.8   5.6e-25   5.1e-21       8     420 ..      45     486 ..      38     498 .. 0.74

  Alignments for each domain:
  == domain 1  score: 75.0 bits;  conditional E-value: 5.6e-25
  AA_permease_2   8 alvigsvigsgifvkn..laasggpalilwvwiavligslavllvyaElssalprsgGiyvytkaafgkkvaflsawfnwfayvpvlasilsvaas 101
                    +++ig  ig++ fv+   ++++ggpa +l   +   +++  v   +aE++  +p +   +  ++      ++f+++w +++  ++ l    ++a++
     EEA21185.1  45 MIAIGGSIGTAMFVSIggALNTGGPAGLLLAYGLYSCVIALVNNSMAEMAIYMPVNASFIRHASVWVDDAWGFMAGWNFFLYEAI-LIPFEISALN 139
                    799*********99989777789999777777777777668999******99******999999888999999999977554444.4333455555 PP

  AA_permease_2 102 yllnalgpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfssl..stetdt........ffpn.. 185
                      + +++    +  +++  i +a++++  +in+ ++++++ + ++l + kill+ i++  + + +v+g+  +++     +++        +  +  
     EEA21185.1 140 LVIRFWS----D-SVPVGAICAACIVTYGIINLAAVRWYGEAEFWLSWGKILLMGIVFSFTFITMVGGNPKHDAygFRYWNNpgpfaeylS--Gga 228
                    5566564....3.4589**********************************7666666666666667777776799555555554455331..222 PP

  AA_permease_2 186 ..gwpgvllgllivlwsfdGfesaanvseevkk.k.dvpkaifigllivlvlyllvniaflgvvpddei......anlsn...lgsvaalffeavg 268
                       w+g+l++l ++ ++++G e+ a v+ e+k  + +v++a   + +  +v++++ ++ + +v+p +            +     s++ + ++++g
     EEA21185.1 229 mgRWKGFLSALWAASFAIVGPEYMAMVAGEAKLpRiTVKRAFKAVYIRFGVFFIGGALCVGIVLPYNDQtlianqG---SgtgAASPYVIAMQNLG 321
                    33666789999999****************9955558999998888888888888888888888874442444321...1222344699******* PP

  AA_permease_2 269 gkvvaiivvilialsllgaintavigssrvlealardgvlPrffakvnkfgspiraiiltaivslillllfllas.saaynfllsvsslgliisyl 363
                       + ++v++l++ s+  a+ ++v+ +sr+l+ la dg  P f++k  k+g pi+++++t+++  +l+ll l +  +  +++l+++ + g ii y+
     EEA21185.1 322 VNGLPHLVNALLVTSIYSAGDAYVYCASRTLHGLASDGHAPAFLKKCTKKGVPIYCLMITMLFP-FLSLLQLSNGaYVVLSWLVNIVTAGGIIDYI 416
                    ***************************************************************9.5566665433688899********9999777 PP

  AA_permease_2 364 ll.iigalilrkkrphl.kr....pgki..lvaiigalfllfll.....valffppkgpatqss.liytii 420
                    ++ +++ +++r ++ +  +r    ++++  ++++++al++ + +     +++f +p   +++s  + y+++
     EEA21185.1 417 IIcVNYIFFWRACKAQGvNRrefsYYAYlqPWSTVFALCFEICVvvcygYVNF-MPGSFDISSFfTHYAMV 486
                    76599999*****9977755588844432344444433333333123334444.44555544431233322 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (555 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       556  (0.0310112); expected 358.6 (0.02)
Passed bias filter:                      247  (0.0137766); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.30s 00:00:00.90 Elapsed: 00:00:00.48
# Mc/sec: 3453.50
//
Query:       EEA21186.1  [L=190]
Description: endo-1,4-beta-xylanase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.5e-44  149.1  17.7    2.8e-38  131.3   8.3    3.0  2  Glyco_hydro_11  Glycosyl hydrolases family 11


Domain annotation for each model (and alignments):
>> Glyco_hydro_11  Glycosyl hydrolases family 11
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   1.8     1e-08   0.00018       2      29 ..      45      72 ..      44      75 .. 0.93
   2 !  131.3   8.3   1.6e-42   2.8e-38      49     178 .]      73     188 ..      71     188 .. 0.97

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 1e-08
                    ---EEEEEECCCSEEEEEC-TTTEEEEE CS
  Glyco_hydro_11  2 ngyyyslwkdgggsvtytngaggsysvs 29
                    +gyyys+w++ggg++tytnga+g+ysv+
      EEA21186.1 45 GGYYYSFWTNGGGEITYTNGANGEYSVK 72
                    79************************98 PP

  == domain 2  score: 131.3 bits;  conditional E-value: 1.6e-42
                     EEEEEEEEEECCEEEEEEEEEECTTTEEEEEEEEESSS-HHHHSEEEEEEEETTEEEEEEEEEEEEEEETTEEEEEEEEEEEESS--SCEEEEHH CS
  Glyco_hydro_11  49 tikYsgtyspsgnsylavYGWtrnplvEYYivenwgsynpssgatkkgtvtsdgatYdiykstrvnqpsieGtatfqqywSvrqskrtsgtitva 143
                      ++Ysg+++p+gn+ylavYGWt +plvE+Yi+e++g+yn ssg t+ g+vt+dg+tYd y+ +r              ywSvr++kr +gtit+ 
      EEA21186.1  73 IVTYSGEFDPTGNAYLAVYGWTADPLVEHYILESYGTYNQSSGLTSLGQVTTDGGTYDSYSIQR--------------YWSVRTEKRVGGTITTV 153
                     589********************************************************99887..............***************** PP

                     HHHHHHHHCT---SEECEEEEEEEEEEEEEEEEEE CS
  Glyco_hydro_11 144 nhfkaWaslGlklgklnyqvlavEgyqssGsasit 178
                     nhf+aW++lGl++g++ny+++++Egy+ssGs++it
      EEA21186.1 154 NHFAAWKALGLEMGTYNYMIVSTEGYESSGSSTIT 188
                     *******************************9886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (190 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       361  (0.020135); expected 358.6 (0.02)
Passed bias filter:                      233  (0.0129957); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1262.88
//
Query:       EEA21187.1  [L=464]
Description: benzoate 4-monooxygenase cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.4e-60  204.6   0.0    3.1e-60  204.2   0.0    1.0  1  p450       Cytochrome P450
  ------ inclusion threshold ------
      0.088   13.2   0.0       0.17   12.3   0.0    1.4  1  CpxA_peri  Two-component sensor protein CpxA, periplasmic dom
       0.15   11.8   0.1       0.29   10.9   0.1    1.4  1  TPR_11     TPR repeat


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  204.2   0.0   5.2e-64   3.1e-60      22     411 ..      67     431 ..      53     431 .. 0.85

  Alignments for each domain:
  == domain 1  score: 204.2 bits;  conditional E-value: 5.2e-64
                 HHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHHHHHHHHHTSHSTTTHHHHHHH CS
        p450  22 lhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkklRrfltptltsfgklsleelvee 120
                 +  +++kl++kygp++r+ + + ++  ++  + +++v ++         +++ ++ s ++   + ++ ++ ++++  Rr+l+ + + +   +l  lv  
  EEA21187.1  67 RPVYVHKLHEKYGPVVRISPYELDISEIYAVKEIHRVGGHY--------RKSDFYRSIRHRSIRTLFSTTNPQHHVVRRRLLSAGMAH---TLATLVRL 154
                 45679*******************99999666666666666........3445666666677788888888*************9999...45555555 PP

                 HHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCCCHHHTCCSCHHHHHHHHHHHHHHHH CS
        p450 121 eaedlveklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelssllskssvqllllfpllkylptkllrklkeavkklkdl 219
                  ++++ +++    + ++ +d++++ + +a+dvig++ Fg +f++le+ + +++vk  e++ss+++ ++  +  l+     lp +l+++++ea ++++++
  EEA21187.1 155 TIKQMDDEM----SRRGAVDVFKWWTFMATDVIGELGFGQSFQTLEHGEKTQYVKNLENVSSFMAIRV-IFPTLIAYSALLPIPLFKRVQEAGRRMAQY 248
                 555555555....5555589****************************************99885544.444444456779****************** PP

                 HHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCT.SSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHCCTTTT-HHHH CS
        p450 220 ldklieerretldsakksrrdfldalllakkekkge.sklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklreEidevlgdkreptydd 317
                 + + i++ ++ ++++ +++++ l   + +     g+ + l  +e+  +++  ++aG+dTt+ tl++      ++P + +kl  E+    +d   +t+d 
  EEA21187.1 249 AHQAIRNYQSVIEKNPDNPKKTLFTKMFN-----GGpEGLEFQEIIPEAGGYIVAGSDTTAITLTYLVWAVCRKPLIRDKLVAEVSALPPD---VTQDS 339
                 ************99933333333333333.....34489*********************************************9988899...89*** PP

                 CCT-HHHHHHHHHHHHHSCSSTTEEEEESSS.CEEETTEEE-TT-EEEEEHHHHHT-TTTSSSTTS--GGGGB-TTSCTESSCTT--TTEEGGGS CS
        p450 318 lqklpyldavikEtLRlhpvvplllpRevtk.dvvirgylipkGtevivnlyalhrdpevfpnPeeFdpeRFldekgnskrksfaflPFGaGpRn 411
                 + +lpyl++vi+E+LR+h++vp+ lpR+++    ++ gy ip G +v++ +y+lhr+p+vfpnP+ F+p+R+++ ++     ++ f+PFG G R+
  EEA21187.1 340 VRDLPYLNQVIQEALRIHSAVPSALPRAAPPeGASLAGYRIPGGVTVSTQAYTLHRNPDVFPNPHIFNPSRWENPSK---EMKHVFMPFGGGSRS 431
                 ****************************97659******************************************87...7899*********95 PP

>> CpxA_peri  Two-component sensor protein CpxA, periplasmic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   2.8e-05      0.17      69     105 ..     244     281 ..     238     288 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 2.8e-05
                 -S-HHHHHHHHHHHHH-S.-TTS-EEEEETTEEEEEEE CS
   CpxA_peri  69 kradfklkalrnfvtsie.spekPkqkLYGrymlaGPl 105
                 + a++  +a+rn+ ++ie +p++Pk+ L+ ++   GP 
  EEA21187.1 244 RMAQYAHQAIRNYQSVIEkNPDNPKKTLFTKMFNGGPE 281
                 6788999**********9468**********9999995 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.1   4.8e-05      0.29      12      28 ..     251     267 ..     250     268 .. 0.95

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 4.8e-05
      TPR_11  12 eAieaYkkAlkldPdna 28 
                 +Ai +Y+  ++ +Pdn+
  EEA21187.1 251 QAIRNYQSVIEKNPDNP 267
                 7***************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (464 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       357  (0.0199119); expected 358.6 (0.02)
Passed bias filter:                      344  (0.0191868); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3222.41
//
Query:       EEA21188.1  [L=709]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.1e-06   26.5   0.0    3.2e-06   25.9   0.0    1.2  1  Cep3          Centromere DNA-binding protein complex CBF3 sub
    2.6e-05   24.2   7.4    4.8e-05   23.4   7.4    1.5  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
    0.00011   21.3   0.5    0.00021   20.4   0.5    1.5  1  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Cep3  Centromere DNA-binding protein complex CBF3 subunit B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.9   0.0   5.4e-10   3.2e-06     104     208 ..     238     342 ..     217     371 .. 0.88

  Alignments for each domain:
  == domain 1  score: 25.9 bits;  conditional E-value: 5.4e-10
                 -GGGTHHHHHHHHHHHHHHHHHHHTTTTTS--HHHHHHHHHHTTTTHHHHSHHHHHHHHHHHHHHHHTT-----S--TTS-HHHHHHHHHHHHHHHHHH CS
        Cep3 104 elteelqlelyegflkttitqlkkanfmanpdirliQiyliLsnTsflfeensladslllqclhvaKlfkiddfkplvedsaalrlskltleklwyrlc 202
                  ++++ +  + +   k++++ l++an++an  +  +Q    ++   ++  +++  + +l  +++++  +  + + +  +d ++  ++++t +++w +lc
  EEA21188.1 238 GFEDSERAVIAQRWFKAALVCLNRANYTANHSVYAVQCIATMTISAHMLGHSNSHSVMLATAIRISQSLGFHRLGSAKQDHPSNGITRETGRRVWTQLC 336
                 5677888899999************************************************************************************** PP

                 HHHHCT CS
        Cep3 203 ilDYlq 208
                 ++D+++
  EEA21188.1 337 VQDWFS 342
                 ***874 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.4   7.4   8.1e-09   4.8e-05       2      37 ..      11      45 ..      10      48 .. 0.92

  Alignments for each domain:
  == domain 1  score: 23.4 bits;  conditional E-value: 8.1e-09
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfysess 37
                aC +C ++K+KCd+  P  +nC ++++ C  ++++ 
  EEA21188.1 11 ACAECNRRKIKCDKVLP-YRNCTRRGSSCYRNDQPN 45
                9****************.9**********9888765 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.5   3.5e-08   0.00021      38     156 ..     216     332 ..     191     410 .. 0.84

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 3.5e-08
  Fungal_trans  38 llllailalGalfsesetkesnssltsesqefiafplraeili.....hedfsspssslwilqsLlllelyektssdralherhhgvavrlarslgL 129
                   +ll++ila  +++++  t+ s+  + se+   i   +r+ +        ++++ + s ++++q+   + +   +++  ++h  ++ +a+r+++slg+
    EEA21188.1 216 GLLFSILAGSMTCAPRLTAHSWGFEDSER-AVI--AQRWFKAAlvclnRANYTANHS-VYAVQCIATMTISAHMLGHSNSHSVMLATAIRISQSLGF 308
                   79999999999999999999999999988.555..3444444466777777888888.*************************************** PP

  Fungal_trans 130 hrnpsyvgkkslwklweeeaesrrRlw 156
                   hr  s ++++  +   +  +e+ rR+w
    EEA21188.1 309 HRLGSAKQDH--PSNGIT-RETGRRVW 332
                   ***9999964..444455.77777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (709 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       445  (0.0248201); expected 358.6 (0.02)
Passed bias filter:                      339  (0.0189079); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.31s 00:00:00.90 Elapsed: 00:00:00.46
# Mc/sec: 4649.54
//
Query:       EEA21189.1  [L=347]
Description: allantoin permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.3e-52  177.8  13.3    4.4e-52  177.3  13.3    1.2  1  Transp_cyt_pur  Permease for cytosine/purines, uracil, thiami
  ------ inclusion threshold ------
      0.016   15.4   0.1      0.016   15.4   0.1    2.9  3  DUF5518         Family of unknown function (DUF5518)


Domain annotation for each model (and alignments):
>> Transp_cyt_pur  Permease for cytosine/purines, uracil, thiamine, allantoin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  177.3  13.3   4.9e-56   4.4e-52     163     438 ..       2     285 ..       1     287 [. 0.94

  Alignments for each domain:
  == domain 1  score: 177.3 bits;  conditional E-value: 4.9e-56
  Transp_cyt_pur 163 fviaallvpvaafgfliwalvkaeg.Gpvldkavklgkse...lflsavagvlagfatlilnapDFtryaktkkssvkiqlvavpllftllllig 253
                     f ++++lvp++a ++ iw+ v+a+g ++++++a  ++ se   l l   +++ +gf+tl++n++DF+r+ k+  s v +ql  +pl+ +++ l+g
      EEA21189.1   2 FIFKSALVPPMALAMVIWISVEAGGgSDLFHAAPTVHGSErawLWLMNMTSITGGFSTLAVNISDFSRFSKKLGSPV-RQLPIIPLFKVITGLFG 95 
                     67899********************7789999999999899*65567889999******************999887.58999************ PP

  Transp_cyt_pur 254 ilvaaaakaayganawspldilakfdet....agvllililvalaqlgvnisanllsagldlaallPkkinikrgsliaavia.lvivpwkllss 343
                     i+ a+a++ +yg+  wspl+i++++       a+ ++ + l  laq+  nisan+ s+++dl++++Pk +ni+rg +++ +i+  + +pw  +++
      EEA21189.1  96 IIAASASQRVYGTILWSPLQIINQWQGSpasrAAAFFCSSLWFLAQICNNISANSFSFANDLTTMCPKWVNIRRGMVVCMLIGgWALCPWIIIKN 190
                     **************************9999***************************************************964899******** PP

  Transp_cyt_pur 344 ssklftaflsllavflspvagviiadyfvvrrgylklaalytrrrgsaYwyrkgvNwravaayivGiaaglvgvagsvg...ikvvkgaeklfdl 435
                      ++ f++f++++++f+ p+ag++  dy+ ++++++ + aly+  + ++Y+y++g+Nwra+a  +v i++ l+g+  +v      +  g+  l+ +
      EEA21189.1 191 GKT-FLSFMGAYSIFMAPIAGILFCDYWLIKHRKYDVPALYD--PRGIYYYQFGTNWRALACNLVVIVPLLPGLVNAVTpntTHINIGLRHLYSI 282
                     ***.**************************************..******************999999999998888877778888899999999 PP

  Transp_cyt_pur 436 syl 438
                     +yl
      EEA21189.1 283 NYL 285
                     997 PP

>> DUF5518  Family of unknown function (DUF5518)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.1      0.58   5.2e+03      55      63 ..      90      98 ..      82     122 .. 0.61
   2 ?   -0.4   0.5      0.13   1.2e+03      54      73 ..     175     187 ..     164     215 .. 0.33
   3 ?   15.4   0.1   1.8e-06     0.016       4      46 ..     284     326 ..     282     331 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.58
     DUF5518 55 laGligaip 63
                ++Gl+g i 
  EEA21189.1 90 ITGLFGIIA 98
                233333332 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.13
     DUF5518  54 alaGligaipvlvlllvlll 73 
                 +l+G       ++ l   ++
  EEA21189.1 175 MLIG-------GWALCPWII 187
                 2222.......222222222 PP

  == domain 3  score: 15.4 bits;  conditional E-value: 1.8e-06
     DUF5518   4 aliGavvaivlslllglllpsvgsllgllvgGlvaGylaggds 46 
                  l+G+ ++++l+++l+++ p  g+l++ +v G+v++ +a  ds
  EEA21189.1 284 YLYGFCLSTALYFALNYFWPHRGTLIPAVVPGVVVAHMAAVDS 326
                 689**********************************998665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (347 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       364  (0.0203023); expected 358.6 (0.02)
Passed bias filter:                      200  (0.0111551); expected 358.6 (0.02)
Passed Vit filter:                        10  (0.000557756); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.48
# Mc/sec: 2165.31
//
Query:       EEA21190.1  [L=607]
Description: pogo transposable element, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    8.1e-26   90.7   0.1      2e-25   89.4   0.0    1.8  2  DDE_1        DDE superfamily endonuclease
    9.1e-10   38.4   0.3    3.4e-09   36.6   0.3    2.1  1  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
        3.8    7.3  14.6          6    6.6  14.6    1.3  1  RR_TM4-6     Ryanodine Receptor TM 4-6


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.4   0.0   3.4e-29     2e-25       2     175 .]     179     354 ..     178     354 .. 0.89
   2 ?   -3.4   0.0       1.1   6.4e+03      29      53 ..     573     597 ..     569     598 .. 0.71

  Alignments for each domain:
  == domain 1  score: 89.4 bits;  conditional E-value: 3.4e-29
       DDE_1   2 erltvllcanaagsekLkplvigkaks..prafkngektkkkldveyksnrkawltssifeeWL.kvfdkrleaekrk..ilLlldssrshetvel.le 94 
                 +++ ++++++ a++  + p +i+ aks  ++ ++    ++++  +++++++ +w+ ++++ +WL +vfdk ++++ ++   lL+ld+++sh t+++ + 
  EEA21190.1 179 REWITTIGCICANGTAISPALIYMAKSgdLQDSWLQDFDPNQHRCHFTASESGWTNNEVGFAWLvNVFDKETKSQASRgwRLLILDGHGSHVTMKFiNY 277
                 678999****************977753378899999************************************666652267**************9** PP

       DDE_1  95 selqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                 ++++ i l+++Pa+s+++lqPld+ ++s+l + Y +ql + +++  +        lt +d+++   ++w+  +++e+i saf
  EEA21190.1 278 CDSNRILLAIFPAHSTHTLQPLDVAIFSPLSTAYTEQL-RRFINDCQGFTR----LTKRDFFRLFWASWEaTFTSENILSAF 354
                 **********************************8765.556666655555....9**************99******9987 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 1.1
       DDE_1  29 prafkngektkkkldveyksnrkaw 53 
                  +   +++++++  +v ++ nr+++
  EEA21190.1 573 VKPKAQPQAHTEDNGVVFTTNRRGR 597
                 3444445589999999999999997 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.6   0.3   5.7e-13   3.4e-09       2      60 ..      45      94 ..      44     101 .. 0.92

  Alignments for each domain:
  == domain 1  score: 36.6 bits;  conditional E-value: 5.7e-13
                 HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT CS
  HTH_Tnp_Tc5  2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh 60
                 +e+ +aL++Wi+ql+erg p+t++++ + A+e+         + + ++k+W  r++k h
   EEA21190.1 45 KEQSRALIKWINQLTERGLPPTNSMLENFAREI---------SGKEPGKNWASRWLKAH 94
                 799******************************.........67889**********99 PP

>> RR_TM4-6  Ryanodine Receptor TM 4-6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6  14.6     0.001         6      50     163 ..     430     545 ..     400     586 .. 0.46

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.001
                 XXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXX.......XXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXX..........XXXX CS
    RR_TM4-6  50 ldlkkeggqykvvakkseagLgDlseteaeespt.......pelkkklaeeeeaeeekeeeeepeaeaeekadaengekeekekekeeeekeseeeeee 141
                 l++++eg + ++++ k+ +  g l      ++++       p++ ++  ++  +++e++++e+ ++++ +k ++ +  k+ ke+e  ++e+++  +e++
  EEA21190.1 430 LKTENEGLKRALIHAKKRPTKGKLLLFDIPTENEggalfmsPSKVQQARDNILKKDEQATQEQARKDD-KKLQQ-QLTKQAKEQE--KAERAQIRQEKR 524
                 55555666555555555555555443333333333444444333333333344444444444444443.33222.2222222222..122222222222 PP

                 XXXXXXXXXXXXXXXXXXXXX- CS
    RR_TM4-6 142 kkkkkkakskkkeeaeaeesel 163
                 ++  ++ak+k+   ++++e + 
  EEA21190.1 525 EQRLQEAKEKQRL-KDEQELAK 545
                 2211111111111.12222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (607 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3079  (0.171733); expected 358.6 (0.02)
Passed bias filter:                      878  (0.0489709); expected 358.6 (0.02)
Passed Vit filter:                       171  (0.00953762); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.88u 0.33s 00:00:01.21 Elapsed: 00:00:00.48
# Mc/sec: 3791.36
//
Query:       EEA21191.1  [L=411]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-32  113.6   0.1    1.9e-32  113.1   0.1    1.1  1  TauD      Taurine catabolism dioxygenase TauD, TfdA family


Domain annotation for each model (and alignments):
>> TauD  Taurine catabolism dioxygenase TauD, TfdA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.1   0.1   1.1e-36   1.9e-32       8     267 ..      46     401 ..      38     402 .. 0.86

  Alignments for each domain:
  == domain 1  score: 113.1 bits;  conditional E-value: 1.1e-36
        TauD   8 k..fgae..gvdlsdleslddelkeelrellaeygvvvfrg.fpl.speqqlefarrfG......................plygtpgrgtntkygevl 78 
                 k  fgae  g+dl++   ++++++e + ++l++++++vf+  +++  p+qq ++++ f+                       +yg p+r+++  +++v+
  EEA21191.1  46 KvdFGAEvcGIDLNN---FTSADFELISDALHKHKLLVFKEqQDMlMPKQQYRLTACFDpdentggfahgadpvllykngvTIYGLPNRPAINAQPQVH 141
                 2559***********...56666******************55669************88899999********************************* PP

        TauD  79 d..vssvyesadianlayttll..............................wHtDls.ylesppgiqlLhcleapa...........tG.......Ge 126
                 +  + +v++++   +      +                              wH D s y+  pp++ +L +++ p+           tG       G+
  EEA21191.1 142 IlgRGEVPTNHFDFPPG----FkvkgidhvdfhipphipqeerdlgasrfyqWHWDGSlYNIPPPRVGCLLAVRTPKgpdvtvhwgdgTGqtmkiapGA 236
                 *7633333333333323....24444778888899999******************999****************888999888776555888888888 PP

        TauD 127 tpfvDgraaynaLpeelpellegltavrvyyhyrg................gglrteqelpavdkhprtghpvvrthpvltgrkallvn..ppfatri. 206
                  + v+g +a++ L++++++ +   +++++++  ++                g +++  +l++++k+ + + p+v+t+pv tg+k+l+v+   +f+ ++ 
  EEA21191.1 237 RAMVSGSRALELLDPDMRQIVMHSRIEYAPHAFQWmstarsvqlghileteGCEMPLDKLSPWTKDNVCIYPMVWTNPV-TGEKSLQVHgqGAFKLYLk 334
                 89*******************9999999999999999*****************************************8.*********8669999995 PP

        TauD 207 .eglgt.......peskelldaleelledpeftyrfqwqeGdlvifdNrrvlHgrtafdeg.eeRhllrc 267
                      +        + ke+ ++ ++ + +pe+ y ++ +e d++++ Nr+++H+ t+f+e   +R +++c
  EEA21191.1 335 dG---PdgeekvlSDLKEVRAFMHRPVLSPENIYPHPHKEQDVILWYNRALWHSITEFPESyGPRIMHQC 401
                 42...324444446666666666666666*****************************5445689**999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (411 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       299  (0.0166769); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.48
# Mc/sec: 2560.02
//
Query:       EEA21192.1  [L=300]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.5e-18   67.0   0.0    1.8e-18   66.7   0.0    1.1  1  Hydrolase_4    Serine aminopeptidase, S33
    8.4e-14   52.7   0.1      1e-13   52.5   0.1    1.1  1  Abhydrolase_6  Alpha/beta hydrolase family
    1.1e-12   48.2   0.0    1.1e-08   35.1   0.1    2.5  2  Abhydrolase_1  alpha/beta hydrolase fold
    1.4e-05   24.9   0.0    0.00035   20.4   0.0    2.5  3  Abhydrolase_5  Alpha/beta hydrolase family
    3.6e-05   23.0   0.0    9.7e-05   21.6   0.0    1.7  1  DUF1749        Protein of unknown function (DUF1749)
     0.0011   18.6   0.0     0.0013   18.3   0.0    1.2  1  LIDHydrolase   Lipid-droplet associated hydrolase
     0.0025   17.7   0.1      0.008   16.0   0.0    1.7  2  Ser_hydrolase  Serine hydrolase
       0.01   15.5   0.0      0.017   14.8   0.0    1.3  1  Esterase       Putative esterase
  ------ inclusion threshold ------
      0.012   14.4   0.0      0.075   11.7   0.0    2.0  2  Ndr            Ndr family
      0.015   15.0   0.0       0.02   14.6   0.0    1.3  1  PGAP1          PGAP1-like protein
      0.019   15.0   0.0      0.033   14.3   0.0    1.4  1  Abhydrolase_4  TAP-like protein
      0.022   14.5   0.0       0.67    9.7   0.0    2.2  2  Abhydrolase_2  Phospholipase/Carboxylesterase
      0.038   14.1   0.0       0.13   12.4   0.0    1.8  1  Thioesterase   Thioesterase domain
      0.039   13.5   0.0       0.17   11.4   0.0    2.1  3  DLH            Dienelactone hydrolase family
       0.11   12.4   0.0       0.19   11.6   0.0    1.4  1  Lipase_3       Lipase (class 3)


Domain annotation for each model (and alignments):
>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.7   0.0   1.5e-21   1.8e-18       6     235 ..      30     277 ..      26     282 .. 0.85

  Alignments for each domain:
  == domain 1  score: 66.7 bits;  conditional E-value: 1.5e-21
  Hydrolase_4   6 vvvlvHGlaehsgryaelaeaLaaqGfavyalDhrGhGrse..gkrghvpsfddyvdDlaafvekvk.eehpel.......plfllGhSmGGlially 93 
                  +++l+H l+ + + +  l  +L  +    + +D   +G+++         s+ +y+dDl+++v  ++ + ++++       +++++GhS+G++ia++y
   EEA21192.1  30 LIILLHDLGGSTETFTPLLPYLYPETNRLVSVDLEAFGKTGlsS-PDVHISIPRYIDDLDSIVASLQgS-ERKQdgedsprKIVIIGHSLGSTIAMHY 125
                  68999999999999**************************8633.33445899**********988853.333336788999**************** PP

  Hydrolase_4  94 llrypdkvaglilsaPalkikaklkappllklllkllgkllpklqv.............snnlkadslsrdpevvaayeadplv.hgkitvrlllell 177
                  ++++p  ++gl+l ++  +i++   +p + + +l l+ k+  +                +++  ++   +++e++ ++ +   + +++     + e++
   EEA21192.1 126 AAEHPMTISGLVLLGAGRSIAH---IPTARERMLSLATKARTEGISavadvaaisnfppPDQWPSTTTIKKQEELHETVRRAVMnCEAEAYAKACEAV 220
                  *****************99985...444444444444444333222466788889999989999999999******99999999999999999***** PP

  Hydrolase_4 178 damkrleeraakitlPllllhGeaDkvvdpeasrelyerlgskdktlklypglyHell 235
                   ++++l  +  +it+P lll G+ D + +p+ s  l + +g  + ++ + +g  H+++
   EEA21192.1 221 AGLDHLDPEYGNITAPALLLAGSGDVISPPDRSMGLKDLIGC-NARVMILDGVGHQMV 277
                  *****************************************7.************986 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.5   0.1   8.3e-17     1e-13       1     213 [.      31     280 ..      31     287 .. 0.60

  Alignments for each domain:
  == domain 1  score: 52.5 bits;  conditional E-value: 8.3e-17
                    EEEE--GC.....GCHHHHHHHHCCT.CEEEEE--TTST....S-GGCS--HHHCHHH.HHHHCCTT...........TTSEEEEEETCHHHHHHH CS
  Abhydrolase_6   1 vlllHGagssassWlvapLaallaag.vhvlapDlpGhG....rsdpppldledladl.aalldelaa.........gggpvvlvGHSlGGalala 81 
                    ++llH +g+s + +   pL+++l     + +++Dl  +G    +s++ + + +++ d+ + ++++l +         +++++v++GHSlG ++a++
     EEA21192.1  31 IILLHDLGGSTETFT--PLLPYLYPEtNRLVSVDLEAFGktglSSPDVHISIPRYIDDlDSIVASLQGserkqdgedSPRKIVIIGHSLGSTIAMH 124
                    79***7778879997..77666666665669*******96666667777777775444488999998899999*99999999************** PP

                    HHHCC.......EE.EEES-..----TTTS----TTHHHHHH..................TT-C.CCCHCCH..........S-HSCCCCHHHCCC CS
  Abhydrolase_6  82 aapla.....lvvg.vlldppptalpagllaaalelllalla..................llrl.lawlsre..........plprlfladedada 142
                       +a      ++g vll +   +  ++ ++ a+e +l l +                     + ++w+s+            ++r  +++e+  +
     EEA21192.1 125 ---YAaehpmTISGlVLLGA---GRSIAHIPTARERMLSLATkartegisavadvaaisnFP-PpDQWPSTTtikkqeelheTVRRAVMNCEA--E 211
                    ...44444688888999999...444444333333333333311111222222222222122.135666322222333344434444444444..5 PP

                    CHCHCCCGHHHHCCHHCHTTCCHHTT-TTGCEEE.CTT-CHHHHCHHCCCH.....STTEEETCE...SSS.-HHHHS CS
  Abhydrolase_6 143 awrarlarlaallaglgllpaaawadlpvpllvl.ggeDplvprllerlla.....qagarlpvvlpgaGH.lphlee 213
                    a++ +  ++a l+  +      ++  +++p l+l g++D + p+   r +         ar+  +l g GH ++++ +
     EEA21192.1 212 AYAKACEAVAGLDHLDP-----EYGNITAPALLLaGSGDVISPPD--RSMGlkdliGCNARV-MILDGVGHqMVLQ-D 280
                    55555544444444444.....99999999988855777777744..555542322255555.9999****87776.4 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.1   0.1   9.1e-12   1.1e-08       1     119 [.      29     153 ..      29     165 .. 0.71
   2 !   10.5   0.0   0.00029      0.35     207     256 ..     230     280 ..     182     281 .. 0.75

  Alignments for each domain:
  == domain 1  score: 35.1 bits;  conditional E-value: 9.1e-12
                    SEEEEE-STTTCGGGGTTGHHHHHHHHTTSEEEEEEETTSTTSSSTTTGB....CHH..SHHHHHHHHH.HHHHHCT...TSSEEEEEETHHHHHH CS
  Abhydrolase_1   1 pvlvilhGlpgssdvwaerglapaLakdgfdvillDlrGvgySspapacin...ddy..gtasvaddld.rildalg...ddkltlvGhSmGGmia 87 
                    p++++lh l+gs + +    l p+L  +  +++ +Dl  +g++  ++  ++   ++y   ++s+ ++l+   + + g    +k++++GhS+G++ia
     EEA21192.1  29 PLIILLHDLGGSTETFTP--LLPYLYPETNRLVSVDLEAFGKTGLSSPDVHisiPRYidDLDSIVASLQgSERKQDGedsPRKIVIIGHSLGSTIA 122
                    678999999999999999..99999999999999999999999877777556665552222333333333113333211146899*********** PP

                    HHHHHHHGGGEEEEEEESECSSCCHHHHHHHH CS
  Abhydrolase_1  88 layaaeyperVkalvllgaidpaaslieaqrq 119
                    ++yaae+p  +++lvllga   ++++i ++r 
     EEA21192.1 123 MHYAAEHPMTISGLVLLGA-GRSIAHIPTARE 153
                    *******************.555555555554 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00029
                    THHHHSEEEEEEETTCSSSCHHHHHHHHHC..HTSEEEEEEETCSSSHHHHS CS
  Abhydrolase_1 207 lknvlaptlvisgtsDplvppkaledlaql..lpkkrlvvisdagHlafleg 256
                      n++ap+l+++g+ D + pp+ +  l++l  ++  r+ ++++ gH  +l++
     EEA21192.1 230 YGNITAPALLLAGSGDVISPPDRSMGLKDLigCNA-RVMILDGVGHQMVLQD 280
                    447999************************66666.**********998875 PP

>> Abhydrolase_5  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       3.5   4.2e+03      48      68 ..      19      39 ..      12      42 .. 0.58
   2 !   20.4   0.0   2.9e-07   0.00035      51     108 ..     104     160 ..      84     181 .. 0.81
   3 ?    1.5   0.0      0.19   2.3e+02      95     140 ..     229     274 ..     207     277 .. 0.88

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 3.5
  Abhydrolase_5 48 eiikeapklekfvvgGhslGG 68
                   +ii++ ++l  +++  h lGG
     EEA21192.1 19 HIIEAGNQLGPLIILLHDLGG 39
                   455555566666666666666 PP

  == domain 2  score: 20.4 bits;  conditional E-value: 2.9e-07
  Abhydrolase_5  51 keapklekfvvgGhslGGvvasrfaaeee.kiegvvflasYPekdelselskkvlsivg 108
                    ++ p  +k v+ GhslG  +a ++aae+  +i g+v+l++  +  ++ ++  ++ls+ +
     EEA21192.1 104 EDSP--RKIVIIGHSLGSTIAMHYAAEHPmTISGLVLLGAGRSIAHIPTARERMLSLAT 160
                    4455..589*******************65*********98887888888888888764 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.19
  Abhydrolase_5  95 elselskkvlsivgteDgvlnvkslekakkflpkdtkvvsieGgnh 140
                    e+ + + ++l + g+ D + + ++    k+ +  +++v+ ++G  h
     EEA21192.1 229 EYGNITAPALLLAGSGDVISPPDRSMGLKDLIGCNARVMILDGVGH 274
                    567788999999*****************************99998 PP

>> DUF1749  Protein of unknown function (DUF1749)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.6   0.0   8.1e-08   9.7e-05      80     139 ..      80     138 ..      65     257 .. 0.69

  Alignments for each domain:
  == domain 1  score: 21.6 bits;  conditional E-value: 8.1e-08
     DUF1749  80 LkrDaeeieklveYlkktk...sGeekkekvvlmGHstGsqdvlyYltssnerdrekvdgail 139
                 + r  ++++++v  l+  +    Ge + +k+v++GHs Gs   ++Y+ ++      +++g +l
  EEA21192.1  80 IPRYIDDLDSIVASLQGSErkqDGEDSPRKIVIIGHSLGSTIAMHYAAEHP----MTISGLVL 138
                 5566788888888888665556899*********************99883....34444443 PP

>> LIDHydrolase  Lipid-droplet associated hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   1.1e-06    0.0013      79     117 ..     102     139 ..      81     208 .. 0.86

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 1.1e-06
  LIDHydrolase  79 aksekdvklilvGHSvGaYialevlkrlsersikkvvlL 117
                   + +++ +k++++GHS G+ ia++ + +++   i+++vlL
    EEA21192.1 102 DGEDSPRKIVIIGHSLGSTIAMHYAAEHPMT-ISGLVLL 139
                   5677889***********************8.9999998 PP

>> Ser_hydrolase  Serine hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   6.7e-06     0.008      51      93 ..     104     146 ..      86     178 .. 0.77
   2 ?   -1.3   0.0       1.4   1.7e+03      76     152 ..     196     274 ..     184     279 .. 0.58

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 6.7e-06
                    HC-STTEEEEEETCHHHHHHHHHHHTTSSSEEEEEEE.T--SGG CS
  Ser_hydrolase  51 eaaeekvvlvAHSlgclavlhaaelqlakkvagalLV.apadve 93 
                    e +++k+v++ HSlg  +++h+a ++++  + g +L  a+ +++
     EEA21192.1 104 EDSPRKIVIIGHSLGSTIAMHYA-AEHPMTISGLVLLgAGRSIA 146
                    567889*****************.999999*9976651555554 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.4
                    TTSSSEEEEEEET--SGGS..TT.GGGCGCTTS-SS..HHCCHCEEEEETTBTTC-HHHHHHHHHHCT..-EEEEETT-TT CS
  Ser_hydrolase  76 qlakkvagalLVapadveeeaaklaelaefaplpre..klpfpslvvaSenDpyvsfeeaeelaeawg..aelvdlgeaGH 152
                    +l++ v++a++   a+    a++ +++a  ++l  e  +   p+l++a + D + + +++  l   +g  a+++ l   GH
     EEA21192.1 196 ELHETVRRAVMNCEAEA--YAKACEAVAGLDHLDPEygNITAPALLLAGSGDVISPPDRSMGLKDLIGcnARVMILDGVGH 274
                    55566666666665554..34444444444444443113444557777777777777777777776652244555666666 PP

>> Esterase  Putative esterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   1.4e-05     0.017     114     137 ..     107     130 ..      88     137 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 1.4e-05
                 CCCEEEEEETHHHHHHHHHHHCST CS
    Esterase 114 pdgravaGqSmGGlgALilalkhp 137
                 p++ +++G+S+G ++A+++a++hp
  EEA21192.1 107 PRKIVIIGHSLGSTIAMHYAAEHP 130
                 44489******************9 PP

>> Ndr  Ndr family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0      0.16   1.9e+02       6      44 ..      12      48 ..       8      59 .. 0.78
   2 ?   11.7   0.0   6.2e-05     0.075     100     132 ..     109     141 ..     106     243 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.16
                ETTE.EEEEEEESS--TTS-EEEEE--TT--HHHHTHHHH CS
         Ndr  6 tkcG.svsvtvqGdqeekkpvllTyhDlglnhkscFqelf 44
                t  G +v+++  G+q    p ++  hDlg   ++ F +l+
  EEA21192.1 12 TSNGtKVHIIEAGNQL--GPLIILLHDLGGSTET-FTPLL 48
                5555257888888887..89*********98888.87775 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 6.2e-05
                 -EEEEEETHHHHHHHHHHHHSGGGEEEEEEES- CS
         Ndr 100 sviglGvgaGAyilarfalkhperveglvLini 132
                 +++ +G   G  i +++a++hp +++glvL+ +
  EEA21192.1 109 KIVIIGHSLGSTIAMHYAAEHPMTISGLVLLGA 141
                 57889*************************865 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.0   1.7e-05      0.02      84     127 ..     101     141 ..      79     203 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 1.7e-05
       PGAP1  84 sssekeptsviliGHSmGGivaraaltlknyikqsvntiltlas 127
                 ++ e  p+++++iGHS+G  +a   + +++  + +++ ++ l++
  EEA21192.1 101 QDGEDSPRKIVIIGHSLGSTIA---MHYAAEHPMTISGLVLLGA 141
                 678899***************9...3444444666777777665 PP

>> Abhydrolase_4  TAP-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   2.7e-05     0.033      32      85 ..     232     287 ..     188     297 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2.7e-05
  Abhydrolase_4  32 kgaapvLllqnerDpaTPyegakklakalgg.avlvtvegeGHgala.agntCvdk 85 
                    + +ap+Lll++ +D + P+     l++ +g  a++++ +g GH+++  + + Cv++
     EEA21192.1 232 NITAPALLLAGSGDVISPPDRSMGLKDLIGCnARVMILDGVGHQMVLqDLDWCVRE 287
                    3379*************************988*************99888999965 PP

>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0     0.086     1e+02       5      29 ..      19      43 ..      16      54 .. 0.84
   2 ?    9.7   0.0   0.00056      0.67     104     137 ..     107     140 ..      80     160 .. 0.86

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.086
                   EEE--SS---EEEEEE--TT--SHH CS
  Abhydrolase_2  5 evvspkdkaqavviflHGlGdsgha 29
                    +++++++  +++i+lH lG s + 
     EEA21192.1 19 HIIEAGNQLGPLIILLHDLGGSTET 43
                   68888889999*********88755 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.00056
                    GGGEEEEEETHHHHHHHHHHHT-SS--SEEEEES CS
  Abhydrolase_2 104 ssriiigGFSqGaalalylaltlpkklggivafs 137
                      +i+i+G S G  +a++ a   p  ++g v ++
     EEA21192.1 107 PRKIVIIGHSLGSTIAMHYAAEHPMTISGLVLLG 140
                    568**************************99876 PP

>> Thioesterase  Thioesterase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0    0.0001      0.13       5      85 ..      33     127 ..      29     141 .. 0.64

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.0001
                   EE--TTCCSGGGHHHHHHCTTCEEEEEEECSTTST...........SHHHCTTCHHHHHHHHHHHHHHH-SSS.S..EEEEEETHHHHHHHHHHH CS
  Thioesterase   5 lfppagGsasvfrslasklsdpvvevlavqlpgre...........rdepplesieelaaeyaealrqiqpeg.P..yalfGhSlGgllAfevAr 85 
                   l+++ gGs++ f+ l  +l ++  +++ v l+ ++           +  + ++++++++a++    r++  e+ P   +++GhSlG+++A+  A+
    EEA21192.1  33 LLHDLGGSTETFTPLLPYLYPETNRLVSVDLEAFGktglsspdvhiSIPRYIDDLDSIVASLQGSERKQDGEDsPrkIVIIGHSLGSTIAMHYAA 127
                   566666666666666666666544444444444444343332222222344567777777777777777777766446789**********9987 PP

>> DLH  Dienelactone hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00014      0.17      90     124 ..     100     134 ..      81     172 .. 0.81
   2 ?   -2.7   0.1         3   3.6e+03     162     185 ..     193     216 ..     188     221 .. 0.78
   3 ?   -2.8   0.0       3.1   3.7e+03     142     187 ..     232     274 ..     227     276 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00014
         DLH  90 ksvpevstkkvgvvGfCmGGalalllaaevpevda 124
                 k+++e s+ k++++G  +G ++a+ +aae p+   
  EEA21192.1 100 KQDGEDSPRKIVIIGHSLGSTIAMHYAAEHPMTIS 134
                 566778999********************986544 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 3
         DLH 162 evekleealkaanvdlelkvYpga 185
                 + e+l+e+++ a +++e + Y+ a
  EEA21192.1 193 KQEELHETVRRAVMNCEAEAYAKA 216
                 457899999999999999999877 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 3.1
         DLH 142 kikapilalfgeeDefipadevekleealkaanvdlelkvYpgagH 187
                 +i ap l l+g  D + p d    l+  +   + ++++ + +g+gH
  EEA21192.1 232 NITAPALLLAGSGDVISPPDRSMGLKDLI---GCNARVMILDGVGH 274
                 78899999999999998888777777766...66667777777777 PP

>> Lipase_3  Lipase (class 3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   0.00016      0.19      65      83 ..     108     126 ..      84     132 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00016
                 EEEEEEEETHHHHHHHHHH CS
    Lipase_3  65 ysivvtGHSLGgalAlLaa 83 
                  +iv+ GHSLG+++A+  a
  EEA21192.1 108 RKIVIIGHSLGSTIAMHYA 126
                 68*************8655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (300 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       437  (0.0243739); expected 358.6 (0.02)
Passed bias filter:                      425  (0.0237046); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 2072.61
//
Query:       EEA21193.1  [L=468]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-26   94.4   0.0    1.8e-26   93.6   0.0    1.3  1  TauD      Taurine catabolism dioxygenase TauD, TfdA family


Domain annotation for each model (and alignments):
>> TauD  Taurine catabolism dioxygenase TauD, TfdA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.6   0.0   9.9e-31   1.8e-26       6     266 ..      19     363 ..      14     365 .. 0.77

  Alignments for each domain:
  == domain 1  score: 93.6 bits;  conditional E-value: 9.9e-31
        TauD   6 tpkfgae..gvdlsdleslddelkeelrellaeygvvvfrgf.plspeqqlefarrfG.....................plygtpgrgtntkygevld. 79 
                 + +fga   gvdl+d   ++d++ e l++++ +++vv+++++ +l+p++q e++ r++                     +               v   
  EEA21193.1  19 KYNFGAVitGVDLND---ISDDDPERLKAAVWRHKVVIIKDQsNLDPKKQWELITRLDpkakdghshgsidkfrakggrE---------------VVGi 99 
                 456999988888888...88888******************8577************88888885555555555555551...............4444 PP

        TauD  80 .............vssvyesadianlayttll..............................wHtDls.ylesppgiqlLhcleapa...........t 123
                                    + d+  ++    +                              wH D++ y  +p+ ++ L+c++ p            +
  EEA21193.1 100 pgaenvrligkgfQ-----GTDHYGIK----NhtverglsndfhaippstsdlengitrfqrWHIDAPlYDRDPTWFTSLRCIKLPRgddltieradgS 189
                 44333222221111.....11111111....0222234444555566666777888999999***********************77777777777555 PP

        TauD 124 G.......GetpfvDgraaynaLpeelpellegltavrvyyhyrg......................gglrteqelpavdkhprtghpvvrthpvltgr 193
                 G       G t+f ++ + y+ L +e ++l++   +++++y+y++                      ++l++      ++  p tg++++++h    ++
  EEA21193.1 190 GlnmkcppGRTAFFSTSQLYSLLTPEEKKLVDHSWVEYAPYPYKWiqrckgnsnglglaaggerlsiEELGEFDPAAVKKVNPLTGEKAFQVHGI--CA 286
                 5**********************************************************999999998888888899999999999999999994..44 PP

        TauD 194 kallvn....ppfatrieglgtpeskelldaleelledpeftyrfqwqeGdlvifdNrrvlHgrtafdeg.eeRhllr 266
                 ++l+      +p  +r+ ++ + + + +l+  +++l+ pe+ +  + +eGd++i++N+++ H++ +++++  +R +++
  EEA21193.1 287 RHLFLRssssEPPPPRVIEDVEGIRRFVLNIQRRILR-PEYILLAPVEEGDMLIWHNYGLFHSAIDYPAKlGPRTMHQ 363
                 4444443566455555558888888888888888886.9****************************54456899987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (468 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       234  (0.0130515); expected 358.6 (0.02)
Passed bias filter:                      229  (0.0127726); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 3071.21
//
Query:       EEA21194.1  [L=248]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.1e-14   54.7   0.0    1.5e-14   54.3   0.0    1.1  1  Flavin_Reduct  Flavin reductase like domain


Domain annotation for each model (and alignments):
>> Flavin_Reduct  Flavin reductase like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.3   0.0   8.6e-19   1.5e-14       4     142 ..      22     173 ..      19     185 .. 0.84

  Alignments for each domain:
  == domain 1  score: 54.3 bits;  conditional E-value: 8.6e-19
                    S-EE-EEEEE.EETTEEEEEEESSEEEEETTTTEEEEEEE.....TTSHHHHHHHHHSEEEEEEEBCCGHHHHHHTCS...SCCCCCCCCCCCEEE CS
  Flavin_Reduct   4 vaqpvavvttsvpptsplgatlssftslsldPplvafslr.....lpsstadalkeagefvinllsesqealadafsqksgprtddksifagltwe 94 
                    v++p+ +++t ++++ ++ a++s f  l++dPp v+fs +      ++++  + +++++fv n+   + +++++ ++++ +  ++d+++ a    +
     EEA21194.1  22 VPRPIGWISTRNKDGVDNLAPFSQFNNLTFDPPYVMFSAQqkftgDRKDSVVNAEKTKHFVWNMATWDLREAVNITGEGVP-YGVDEFERASQYIS 116
                    79********99999999**********************6666666*****************999***********888.*****777733333 PP

                    CTCCCS...EEETTCSEEEEEEEEEE......ECCTTEEEEEEEEEEEEESTTECTT CS
  Flavin_Reduct  95 esptga...pallgalasleCqvvgs......velgdhelfigeVvavkvgddadee 142
                    +++ ++   p++ ++++ +eC+ +++       + g+ +++ig+V a++++d+  ++
     EEA21194.1 117 KEQATLmdvPMVRESPVKFECEYHSTirlpgnPPTGTVDIVIGKVIAIHIKDEVLTD 173
                    333333667****************944555555555**************996655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (248 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       290  (0.0161749); expected 358.6 (0.02)
Passed bias filter:                      269  (0.0150036); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.25s 00:00:00.63 Elapsed: 00:00:00.38
# Mc/sec: 1952.65
//
Query:       EEA21195.1  [L=607]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.2e-35  120.8  51.7    1.3e-33  116.4  51.7    2.4  1  MFS_1           Major Facilitator Superfamily
     0.0065   16.7   5.7     0.0065   16.7   5.7    5.0  5  Transgly_assoc  Transglycosylase associated protein
  ------ inclusion threshold ------
       0.34   11.0   0.1       0.34   11.0   0.1    2.8  3  Pox_I5          Poxvirus protein I5


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.4  51.7   2.2e-37   1.3e-33       4     352 ..     117     517 ..     114     518 .. 0.90

  Alignments for each domain:
  == domain 1  score: 116.4 bits;  conditional E-value: 2.2e-37
       MFS_1   4 aaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfasslwlllvlrvlqGlgaga 101
                 +++l+ l+++i+++a+p a++++++ +++ +g+ ++++ l+ +++++++G     f  ++++l++ ++f++g +l+++ a+s+++l+++r+++Glga++
  EEA21195.1 117 VIVLVNLDMNIVATAVP-AITDHFH-TVADVGWYAAAFRLTLCAFQFIFGKTYFLFPVKSIFLTANIVFLFGsALCAT-ATSSTMLVIGRAVTGLGAAG 212
                 6788999**********.*******.******************************9999************666666.46666*************** PP

       MFS_1 102 lfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee............ 188
                 l+++   ++++  p + r+  +gl s+  +++++ gpllgg+l++++ Wr++fyi+  ++ la++l l+ + ++p++ +    ++              
  EEA21195.1 213 LNAGLFNILVQSIPLQVRPIWLGLGSGLEGVSMLSGPLLGGILVQYADWRWCFYINLTLGSLAALLTLFCIHDKPKTTSSAQMTTTQkisdidivsnli 311
                 *****************************************************************97788877777777776666669*********** PP

       MFS_1 189 ............................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsgl 243
                                                              ++g ++++p  ++++++ v   +l++l++++ + +++ ++lp+y q+v g++  
  EEA21195.1 312 fipamvtlflalswggtkykwgsgiiicllvtagvllivfvvnqFRRGDRAALP-PRLMRHRSVAAGFLFMLFMNS-AGQSFEYYLPTYYQTVQGYT-P 407
                 ******************999999999999999999999999885555555555.588888884444444444444.5555****************.7 PP

       MFS_1 244 llaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllllvlvl.iGfglgfvfpsllalasdlappeeagtasglf 341
                  ++++ll  + ++g i+a+lag+ +  lg  ++ lla+ +++++ +gl+ + + +++++ l+++ + +G+g+g+ f+++  +++ ++ p+     ++++
  EEA21195.1 408 AQSSYLLLPFIILGSIGAVLAGFCVSELGYYTPFLLAGTVIMTIGAGLVTTLNVHTNLAKLIGYTCiWGIGYGISFGMSSLAVQTVLAPDDVPLGLSFI 506
                 99999*************************************************9999999955555******************************** PP

       MFS_1 342 ntagslggalg 352
                  +a+s+g +l+
  EEA21195.1 507 FFAQSFGPSLA 517
                 *******9997 PP

>> Transgly_assoc  Transglycosylase associated protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.1      0.23   1.4e+03      25      42 ..     104     121 ..      96     125 .. 0.67
   2 ?   -3.5   0.2       2.2   1.3e+04      26      48 ..     184     206 ..     176     207 .. 0.68
   3 ?    0.3   2.3      0.15   8.9e+02       9      48 ..     316     357 ..     313     358 .. 0.63
   4 !   16.7   5.7   1.1e-06    0.0065       1      37 [.     418     453 ..     418     456 .. 0.97
   5 ?    0.0   0.2      0.18   1.1e+03      27      39 ..     574     586 ..     564     589 .. 0.84

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.23
  Transgly_assoc  25 gelaslivaiiGAiILLf 42 
                     g+  +li+  + A+I+L+
      EEA21195.1 104 GFKFGLIILALSAVIVLV 121
                     444455666678999986 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 2.2
  Transgly_assoc  26 elaslivaiiGAiILLfivrlvr 48 
                      ++s + a+  +   L+i r+v+
      EEA21195.1 184 LFGSALCATATSSTMLVIGRAVT 206
                     55666666666677788888876 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.15
  Transgly_assoc   9 fvGgfllgllgigvgggelaslivaii...GAiILLfivrlvr 48 
                     +v  fl+ ++g+ ++  + +++i++++   G  +++f+v+ +r
      EEA21195.1 316 MVTLFLALSWGG-TKYKWGSGIIICLLvtaGVLLIVFVVNQFR 357
                     566688888888.666777777666542225555566666666 PP

  == domain 4  score: 16.7 bits;  conditional E-value: 1.1e-06
  Transgly_assoc   1 IilGivGAfvGgfllgllgigvgggelaslivaiiGA 37 
                     IilG +GA+++gf  + lg  ++++ la+ ++ +iGA
      EEA21195.1 418 IILGSIGAVLAGFCVSELGY-YTPFLLAGTVIMTIGA 453
                     9*******************.***************9 PP

  == domain 5  score: 0.0 bits;  conditional E-value: 0.18
  Transgly_assoc  27 laslivaiiGAiI 39 
                     ++ ++v++ GA +
      EEA21195.1 574 VWYFVVSLAGATV 586
                     7899*******77 PP

>> Pox_I5  Poxvirus protein I5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.1   5.7e-05      0.34      38      69 ..     292     322 ..     274     323 .. 0.75
   2 ?   -0.8   0.1      0.27   1.6e+03      16      28 ..     338     350 ..     333     386 .. 0.60
   3 ?   -3.7   0.9       2.1   1.3e+04       5      25 ..     446     466 ..     444     469 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 5.7e-05
      Pox_I5  38 tlrsatanrvvrvlelvailifiPGtiiLYaa 69 
                 +++ +t+++ ++ +++v++lifiP  ++L+ a
  EEA21195.1 292 SAQMTTTQK-ISDIDIVSNLIFIPAMVTLFLA 322
                 444444444.5667***************976 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.27
      Pox_I5  16 mllmvisggalvv 28 
                 + l+v +g  l+v
  EEA21195.1 338 ICLLVTAGVLLIV 350
                 4455555555544 PP

  == domain 3  score: -3.7 bits;  conditional E-value: 2.1
      Pox_I5   5 evlsaiglTlLmllmvisgga 25 
                 +v+++ig+ l + l v +++a
  EEA21195.1 446 TVIMTIGAGLVTTLNVHTNLA 466
                 688899999999888888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (607 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       770  (0.0429472); expected 358.6 (0.02)
Passed bias filter:                      359  (0.0200234); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.45
# Mc/sec: 4033.48
//
Query:       EEA21196.1  [L=473]
Description: carboxypeptidase S1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.3e-104  350.9  10.7   1.6e-104  350.6  10.7    1.0  1  Peptidase_S10  Serine carboxypeptidase


Domain annotation for each model (and alignments):
>> Peptidase_S10  Serine carboxypeptidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  350.6  10.7  8.9e-109  1.6e-104       5     418 ..      60     466 ..      56     467 .. 0.90

  Alignments for each domain:
  == domain 1  score: 350.6 bits;  conditional E-value: 8.9e-109
                    ST-SSEEEEEEEECSTTTTEEEEEEEEE-SSGTTTS-EEEEE--TTTB-THHHHHHTTSSEEEETTTTSEEEE-TT-GGGCSEEEEE--STTSTT- CS
  Peptidase_S10   5 etvnfkqysGYldveeeedkslFYwfveseknpeedplvlWLnGGPGCsSldGlleElGPfrvnkdstkkleenpysWnkvanvlfldqPvGvGFS 100
                    +t+ ++qysGYl+v   ++ ++++wf+e+++np+++pl  W+nGGPGCsS++Gl++E+GP+++  ++ +++ +n+ysWn+ an+l++dqP+GvGFS
     EEA21196.1  60 TTPGVNQYSGYLSVG--TNMNMWFWFFEARNNPQQAPLAAWFNGGPGCSSMIGLFQENGPCHFV-NGASTPSLNKYSWNNYANMLYVDQPIGVGFS 152
                    56889**********..89********************************************9.567**************************** PP

                    EETTSSGS--SHHHHHHHHHHHHHHHHHHSTCGTTSEEEEEEETTHHHHHHHHHHHHHTHCCH--S.....STSEEEEEEEESE-SBHHHHHCCHH CS
  Peptidase_S10 101 ysntksdvktddeevaedlyefLkkffekfpeyksrdfyitGESYaGhyvPalakeilkknkkekk.....kkinLkGlligNglideaeqvnsyv 191
                    y +++ +   ++ ++a  ++++L+ f+++fp+y+srdf i +ESY+Ghy P +a+ i ++n + +      ++inL +l + Ng+id a+q ++y+
     EEA21196.1 153 YGTDDVT---STVTAAPYVWKLLQAFYAQFPQYQSRDFAIFTESYGGHYGPEFAAYIQQQNAAITAgsvsgENINLIALGVNNGWIDSAIQEKAYI 245
                    ***9877...9***************************************************998899999************************* PP

                    HHHH...HTTSSHHHHHHHHHHHHEETHHHHHHHHHHHHHHHHHHHHH...........HHHHCHCEETTETTSEETTSSEEHHHCTTCCCCTTTT CS
  Peptidase_S10 192 efay...ehgliseeeyeslkkacekkeeleqesekcanllekaskva...........vekenkglnvynileeccklkaelkksstdaqggedp 273
                    +f+y   +++lis+++  sl +a +  +++ ++++kc ++ ++ ++++             ++ ++ +vy+i+e++                 +dp
     EEA21196.1 246 DFSYnnsYQQLISDSQRTSLLSAYN--NQCLPAIQKCVRTGSNSDCQNadsvcynqiegPISNSGDWDVYDIREPS-----------------NDP 322
                    *7772225789********999995..5699999999999999988654444333333322233455555555555.................9** PP

                    TCHHHHHHHHTSHHHHHHTT--TTSSS--SB-HHH...HHHCTCCC-SBCHHHHHHHHHTT-EEEEEEETT-STT-HHHHHHHHHHTECTTECCSC CS
  Peptidase_S10 274 ydesyvekylnkkeVrkalhvnasvkkweecndsv...feqleddisksveeileellesglrvliynGdvDlicnvlgteawikklelsgkkefr 366
                    y +s +++yl+k+ V ka++++    +++ec +     f +++ d  +s+ + l+ +++sg++vl+++Gd+D icn+lg+  + +++++sg++ef+
     EEA21196.1 323 YPPSTYSTYLSKSAVVKAIGAQ---TSYQECPNAPynkF-ASTGDNPRSFLSTLSSVVQSGINVLVWAGDADWICNWLGNYGVANAVNFSGHAEFS 414
                    ********************75...78****99775533.34556679************************************************ PP

                    CCEEEETTTCESEEEEEEEETTEEEEEETT--SSHHHHSHHHHHHHHHHHHT CS
  Peptidase_S10 367 pwevspkkengqvaGyvkeyenltfltvkgaGHmvPedkpeealqllerfis 418
                    + +  p ++ng++ G +k+ +n++fl+v+gaGH+vP+++pe alq++e++++
     EEA21196.1 415 AKNLAPYTVNGVEKGMFKNVNNFSFLKVYGAGHEVPFYQPETALQVFEQILQ 466
                    ************************************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (473 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       481  (0.026828); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.26s 00:00:00.88 Elapsed: 00:00:00.50
# Mc/sec: 2857.03
//
Query:       EEA21197.1  [L=169]
Description: hypothetical protein PMAA_049950 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (169 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       280  (0.0156172); expected 358.6 (0.02)
Passed bias filter:                      250  (0.0139439); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.46
# Mc/sec: 1097.21
//
Query:       EEA21198.1  [L=934]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.7e-60  204.7   0.0    2.5e-60  204.2   0.0    1.2  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    2.8e-17   63.0   0.0    1.5e-16   60.6   0.0    2.2  2  rve              Integrase core domain
    5.1e-10   39.1   0.3    3.1e-09   36.6   0.1    2.4  2  gag_pre-integrs  GAG-pre-integrase domain
     0.0075   16.0   0.1      0.045   13.5   0.0    2.3  2  rve_3            Integrase core domain
  ------ inclusion threshold ------
      0.023   14.2   0.0      0.051   13.1   0.0    1.5  1  RVT_1            Reverse transcriptase (RNA-dependent DNA pol


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  204.2   0.0   6.9e-64   2.5e-60       2     241 ..     453     692 ..     452     693 .. 0.96

  Alignments for each domain:
  == domain 1  score: 204.2 bits;  conditional E-value: 6.9e-64
       RVT_2   2 tyrlvslPkdrkaigsrWvftkkkddl.kevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeeelvvhqldvdsafLnaeldeevyvkq 99 
                 t+r v+ P ++  i+ +Wvf +k ++  +  ++karlva+Gfsq+ g d++++faPvirl+s+r+l a+aa+++l  h ld   af+ ++ld+++y+  
  EEA21198.1 453 TWRFVKRPDHKAVISCKWVFDIKYQADgRIERFKARLVARGFSQQEGLDFEDTFAPVIRLESLRVLFAIAAMYGLTAHLLDATNAFVGSKLDKQIYMEV 551
                 8**********************988768899******************************************************************* PP

       RVT_2 100 PpGfeidre..eekvykLnkslyGlkqapllWnekidkvLkklgferseaesGlyvrgtgegklivalyvddlliagsdikiledvkkelakkfklkdl 196
                 P G     +  +++v++L +slyGl+q++ lW +k++k+++ +gf++s+a  G ++        i+aly+dd+l+ +++ k +e  k++l++ + +kd 
  EEA21198.1 552 PKGLPKSLQprKDEVCELLQSLYGLRQSANLWCHKVKKFVTSIGFKPSTADPGTFINER---GTIIALYMDDILVFSKNEKAIELTKEKLKEFHPMKDS 647
                 ***97765511688******************************************984...369********************************** PP

       RVT_2 197 gkvskfLGieiaqeaggiklsladyiakvvkkfeltdaktvatPl 241
                 g+v+k LGi i+   g i+l ++ y  +++++f++ ++k+++ Pl
  EEA21198.1 648 GRVNKILGIRITWLDGSIRLDQEFYTIRILEEFDMLESKPQMLPL 692
                 ****************************************99997 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.6   0.0   4.3e-20   1.5e-16       2     115 ..      81     194 ..      80     196 .. 0.94
   2 ?   -2.1   0.0       1.2   4.2e+03      81     100 ..     585     604 ..     578     605 .. 0.87

  Alignments for each domain:
  == domain 1  score: 60.6 bits;  conditional E-value: 4.3e-20
         rve   2 trpgelwqvDvt.vvripdgggkayllvvvddfsrlilaealsdemdastvlalleravarfggve...pervlsDngseytskafrefladlgirvsf 96 
                 ++p e+++vD++  +r ++ g++ay l ++dd++r+ ++++++++   +tv+++l r ++r+  +       ++ Dn++e++  a++ +++dlgi+++f
  EEA21198.1  81 KKPLERVSVDFWgPYR-KGEGKEAYYLSITDDATRFSWIHITDNR-RLETVQRILSRWMRRQERELgvfLVNIRLDNAKEFV--ALKPWAEDLGIDLEF 175
                 589**********888.67777***********************.*************999885599999***********..*************** PP

         rve  97 trpgrpqdnGkvErfhrtl 115
                 t  + p +nG++Er +r+l
  EEA21198.1 176 TEFYTPAQNGVAERLNRLL 194
                 *****************98 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.2
         rve  81 kafrefladlgirvsftrpg 100
                 +++++f+ + g+++s++ pg
  EEA21198.1 585 HKVKKFVTSIGFKPSTADPG 604
                 68899***********9998 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.6   0.1   8.5e-13   3.1e-09      18      67 .]      22      68 ..       6      68 .. 0.85
   2 ?   -1.5   0.0      0.64   2.3e+03      44      60 ..     552     568 ..     549     571 .. 0.85

  Alignments for each domain:
  == domain 1  score: 36.6 bits;  conditional E-value: 8.5e-13
  gag_pre-integrs 18 sknkssinlWHrRLGHpsfsrlkkLfkkgllpglkisksevCeaCqlgKq 67
                     + +  + +l HrR+GH +++r+++L+k+    g+++++s+ Ce+C+++K+
       EEA21198.1 22 QEKQPDWELLHRRFGHAGERRMRRLVKR---LGITFKDSKDCEVCIQAKS 68
                     44677899******************98...688999************6 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.64
  gag_pre-integrs  44 kkgllpglkisksevCe 60 
                      +kgl ++l++ k+evCe
       EEA21198.1 552 PKGLPKSLQPRKDEVCE 568
                      6778889999******9 PP

>> rve_3  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.1      0.69   2.5e+03      30      51 ..     117     138 ..     113     139 .. 0.81
   2 !   13.5   0.0   1.3e-05     0.045       2      27 ..     170     195 ..     169     209 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.69
       rve_3  30 llneelfrslaearekleawre 51 
                 ++  +  r+l++++++l +w +
  EEA21198.1 117 WIHITDNRRLETVQRILSRWMR 138
                 5566677899**********87 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 1.3e-05
       rve_3   2 gielsyiapgkPqqNglvEsfngtlr 27 
                 gi l++++ ++P qNg +E++n+ l 
  EEA21198.1 170 GIDLEFTEFYTPAQNGVAERLNRLLL 195
                 899*******************9876 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   1.4e-05     0.051     159     190 ..     610     641 ..     579     646 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.4e-05
                 ...TEEECTTEEEEEESSHHHHHHHHHHHHHH CS
       RVT_1 159 kgvtllrYaDDililskskeelqelleaveew 190
                  g  +++Y+DDil++sk++++++   e+++e+
  EEA21198.1 610 RGTIIALYMDDILVFSKNEKAIELTKEKLKEF 641
                 48899**************9988777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (934 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       507  (0.0282782); expected 358.6 (0.02)
Passed bias filter:                      449  (0.0250432); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.67u 0.28s 00:00:00.95 Elapsed: 00:00:00.44
# Mc/sec: 6433.33
//
Query:       EEA21199.1  [L=395]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.4e-16   59.7   0.3    3.5e-16   59.1   0.3    1.3  1  Retrotran_gag_2  gag-polypeptide of LTR copia-type
    1.7e-11   43.5   0.1    4.3e-11   42.2   0.1    1.7  1  DUF4219          Domain of unknown function (DUF4219)
    2.3e-06   27.4   1.7    2.3e-06   27.4   1.7    1.8  2  zf-CCHC          Zinc knuckle
  ------ inclusion threshold ------
      0.012   15.7   0.3       0.04   14.1   0.3    1.8  1  CAF1A            Chromatin assembly factor 1 subunit A
      0.015   15.1   1.3      0.033   14.0   1.3    1.5  1  zf-CCHC_6        Zinc knuckle
      0.024   14.2   0.5       0.51    9.9   0.2    2.1  2  Glyco_hydro_32N  Glycosyl hydrolases family 32 N-terminal dom
      0.053   13.3   1.6       0.67    9.7   0.3    2.4  2  zf-CCHC_4        Zinc knuckle
      0.086   12.7   1.2       0.18   11.7   1.2    1.5  1  zf-CCHC_2        Zinc knuckle
       0.12   12.8   0.0       0.33   11.4   0.0    1.7  1  zf-C2HE          C2HE / C2H2 / C2HC zinc-binding finger
       0.37   10.7   2.7        0.9    9.4   2.7    1.7  1  HscB_4_cys       Co-chaperone HscB tetracysteine metal bindin


Domain annotation for each model (and alignments):
>> Retrotran_gag_2  gag-polypeptide of LTR copia-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.1   0.3     2e-19   3.5e-16       1     132 [.      83     216 ..      83     222 .. 0.95

  Alignments for each domain:
  == domain 1  score: 59.1 bits;  conditional E-value: 2e-19
  Retrotran_gag_2   1 wkkkdakalalIvlsisdsllelvkeektakevWdkLkelyekksaankltlrkklfslkmkegesvadhinkleelvneLsalgv...kidde 91 
                      wk+ + +a+ +I+  i+++ +  v+++k + e+W  + + ye+k+    ++ +++ ++ k++ + s++d +++le+l  eL+++ +   k+ + 
       EEA21199.1  83 WKSANGRAKLYILGNIKQDDISTVRDCKLSGEMWAYIRKKYERKTHVDIMMAIQRIVDWKKSAEASMEDSLQQLEQLEAELRDISDgqiKLGEL 176
                      99999*****************************************************************************986555699999 PP

  Retrotran_gag_2  92 dkvvllLasLPesyetfvtaiesseedltleevieklleee 132
                      +++   L+ LP++yet++ ai+  +e++t e+v ++l+ +e
       EEA21199.1 177 MILNFFLRGLPKDYETITYAIMG-SETITRENVLSRLQVQE 216
                      9********************88.9************9877 PP

>> DUF4219  Domain of unknown function (DUF4219)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.2   0.1   2.4e-14   4.3e-11       3      27 .]      38      62 ..      36      62 .. 0.95

  Alignments for each domain:
  == domain 1  score: 42.2 bits;  conditional E-value: 2.4e-14
     DUF4219  3 gtNYatWklrMklyLiaqdLWevVe 27
                ++N ++WklrM+ +L++qd+W+vVe
  EEA21199.1 38 RSNIKNWKLRMQIFLETQDCWDVVE 62
                69**********************8 PP

>> zf-CCHC  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.1       4.6   8.3e+03      14      17 ..     107     110 ..     106     110 .. 0.82
   2 !   27.4   1.7   1.3e-09   2.3e-06       2      18 .]     236     252 ..     235     252 .. 0.95

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 4.6
                 TTST CS
     zf-CCHC  14 rdCp 17 
                 rdC+
  EEA21199.1 107 RDCK 110
                 9**6 PP

  == domain 2  score: 27.4 bits;  conditional E-value: 1.3e-09
                 CTSSSSSSSSTTTTSTS CS
     zf-CCHC   2 kCynCGepGHiardCpk 18 
                 kC+nCG++GH+ ++Cp+
  EEA21199.1 236 KCWNCGKEGHRMSECPE 252
                 8***************6 PP

>> CAF1A  Chromatin assembly factor 1 subunit A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.3   2.2e-05      0.04      18      59 ..     291     331 ..     281     344 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 2.2e-05
       CAF1A  18 tkkskvvgarnPfskdekeldYdyDSdaEWeeeeeeegedle 59 
                 + k++v g ++P + +  + dYd DSda    e +++ge   
  EEA21199.1 291 KDKTQVKGKKKPYRGSARKADYDSDSDAGSTTE-DSDGERAA 331
                 567788889********************9775.55898765 PP

>> zf-CCHC_6  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   1.3   1.8e-05     0.033       2      20 ..     235     251 ..     234     257 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1.8e-05
   zf-CCHC_6   2 vKCknCGAFGHtarSkrCP 20 
                 +KC+nCG  GH++  + CP
  EEA21199.1 235 LKCWNCGKEGHRM--SECP 251
                 7***********9..7898 PP

>> Glyco_hydro_32N  Glycosyl hydrolases family 32 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.2   0.00028      0.51     161     231 ..      39     104 ..      35     161 .. 0.83
   2 ?    2.5   0.0      0.05        90     180     271 ..     245     339 ..     236     354 .. 0.68

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00028
                      SSSSSEEEECCESEECC.TTTEEEEEEEEEEECSTT-ECEEEEEEEEC.STT.TTTTEEEEEEEEEETTTTE CS
  Glyco_hydro_32N 161 kdlkewelaselleskkekggmwEcpdlfeldekdeeekvklvlkvspqgle.dntsqdyyfigkfdaekkk 231
                      +++k+w+l  ++  + +       c d++el ek++++  k+  ++  +g++  n++ + y++g++++++ +
       EEA21199.1  39 SNIKNWKLRMQIFLETQ------DCWDVVELTEKYQKDPEKVQALFAKKGWKsANGRAKLYILGNIKQDDIS 104
                      58999999999998887......6999999999988888999999999999999***********9655444 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.05
                      TTEEEEEEEEEEECSTT-ECEEEEEEEEC.STTTTTTEEEEEEEEEETTTTEEEEC....CCCCEESBSSSS-EEEEEECCTTTCEEEEEEES- CS
  Glyco_hydro_32N 180 ggmwEcpdlfeldekdeeekvklvlkvspqgledntsqdyyfigkfdaekkkftad....eeelkelDyGkdfYAsqtfededkrriligWmge 269
                        m Ecp+  + +++de+ k  +  k   +g +++ +  +   g+  ++k++ + +    ++++++ Dy +d  A  t ed+d++r +   m +
       EEA21199.1 245 HRMSECPEPRSKSDSDETGKQSIRKKSDHRGRKNHRRGRGAREGSG-KDKTQVKGKkkpyRGSARKADYDSDSDAGSTTEDSDGERAARVEMVS 337
                      5677888777777776555555555555555556666666666665.34444444455778999******************997766555555 PP

                      TT CS
  Glyco_hydro_32N 270 wd 271
                      +d
       EEA21199.1 338 PD 339
                      55 PP

>> zf-CCHC_4  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.09   1.6e+02      12      29 ..     108     125 ..     102     127 .. 0.83
   2 ?    9.7   0.3   0.00037      0.67      30      48 ..     232     251 ..     230     252 .. 0.86

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.09
   zf-CCHC_4  12 kikkesGeeatiefkYEr 29 
                 + k+ +  +a i+ kYEr
  EEA21199.1 108 DCKLSGEMWAYIRKKYER 125
                 55666779*********9 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.00037
   zf-CCHC_4  30 Lrsf.CyiCgvlGHsdkrCd 48 
                 +r + C +Cg  GH +++C+
  EEA21199.1 232 IRGLkCWNCGKEGHRMSECP 251
                 56666**************8 PP

>> zf-CCHC_2  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   1.2   9.8e-05      0.18       5      21 .]     236     252 ..     234     252 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 9.8e-05
   zf-CCHC_2   5 vChiCgkkGHyIqdCPt 21 
                 +C  Cgk GH  ++CP+
  EEA21199.1 236 KCWNCGKEGHRMSECPE 252
                 6889************6 PP

>> zf-C2HE  C2HE / C2H2 / C2HC zinc-binding finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00019      0.33      10      52 ..     207     248 ..     203     249 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00019
     zf-C2HE  10 dlpeelekdgeieslseeqskelilktpLkCtrCganfgnkfp 52 
                 +++++l++++ i   +e+  ++ ++ + LkC+ Cg ++g  + 
  EEA21199.1 207 NVLSRLQVQEGILGQKEKVIESANRIRGLKCWNCG-KEGHRMS 248
                 566667777666445788889999999********.9999886 PP

>> HscB_4_cys  Co-chaperone HscB tetracysteine metal binding motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   2.7    0.0005       0.9       2      13 ..     236     247 ..     236     252 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0005
                 B-SSS--B--SS CS
  HscB_4_cys   2 rCWnCGgpgapg 13 
                 +CWnCG+ g  +
  EEA21199.1 236 KCWNCGKEGHRM 247
                 6*****998766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (395 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1192  (0.0664845); expected 358.6 (0.02)
Passed bias filter:                      545  (0.0303977); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.56u 0.25s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 2614.07
//
Query:       EEA21200.1  [L=143]
Description: hypothetical protein PMAA_049980 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (143 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       249  (0.0138881); expected 358.6 (0.02)
Passed bias filter:                      238  (0.0132746); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.39u 0.23s 00:00:00.62 Elapsed: 00:00:00.40
# Mc/sec: 1085.74
//
Query:       EEA21201.1  [L=97]
Description: hypothetical protein PMAA_049990 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
  ------ inclusion threshold ------
      0.028   14.4   0.0      0.044   13.8   0.0    1.2  1  Neuralized  Neuralized


Domain annotation for each model (and alignments):
>> Neuralized  Neuralized
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   2.4e-06     0.044      30      62 ..      63      95 ..      62      97 .] 0.95

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2.4e-06
  Neuralized 30 fssrplrigelfevriekledkwsgsLevGvts 62
                f +rpl+ g+++ v i+ l ++++ ++++G+t 
  EEA21201.1 63 FRQRPLNSGQKVLVTIQGLRRSMAKHMKLGLTD 95
                789****************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (97 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       451  (0.0251548); expected 358.6 (0.02)
Passed bias filter:                      396  (0.0220871); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.35s 00:00:00.92 Elapsed: 00:00:00.57
# Mc/sec: 510.52
//
Query:       EEA21202.1  [L=256]
Description: cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      6e-18   64.8   0.1    8.3e-18   64.4   0.1    1.1  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.4   0.1   4.6e-22   8.3e-18     354     441 ..     122     212 ..     117     223 .. 0.90

  Alignments for each domain:
  == domain 1  score: 64.4 bits;  conditional E-value: 4.6e-22
                 TEEE-TT-EEEEEHHHHHT-TTTS.SSTTS--GGGGB-TTS...CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTST CS
        p450 354 gylipkGtevivnlyalhrdpevf.pnPeeFdpeRFldekg...nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpet 441
                 +y ipkG+ v++n +a+h++p+++ p+ ++Fdp RFl++     + +  +  +l FGaG+ +C+G ++A+  l+++la+++  F++ +++ +
  EEA21202.1 122 HYRIPKGCFVVINQCAIHNNPDYYyPESHRFDPARFLEAPLdvkKYSTAPKPHLNFGAGRCICPGSHVAESGLFIALAKIVWLFDIRPPR-D 212
                 699********************99*************988776445788899********************************99844.3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (256 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       300  (0.0167327); expected 358.6 (0.02)
Passed bias filter:                      291  (0.0162307); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.47
# Mc/sec: 1654.19
//
Query:       EEA21203.1  [L=182]
Description: hypothetical protein PMAA_050010 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (182 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       446  (0.0248759); expected 358.6 (0.02)
Passed bias filter:                      293  (0.0163422); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.41u 0.25s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 1298.35
//
Query:       EEA21204.1  [L=212]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.023   14.5   0.0       0.34   10.7   0.0    2.1  2  THDPS_N   Tetrahydrodipicolinate N-succinyltransferase N-term


Domain annotation for each model (and alignments):
>> THDPS_N  Tetrahydrodipicolinate N-succinyltransferase N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0     0.011     2e+02     121     154 ..      65      98 ..      34     105 .. 0.76
   2 ?   10.7   0.0   1.9e-05      0.34     112     159 ..     155     205 ..     117     208 .. 0.79

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.011
                 .....SEEEEEESS-----SHHHHHHHHHHHHTT CS
     THDPS_N 121 kqkekeyrlvvlyeDkackSvesvYlKLlaLSlg 154
                 + ++ + r+v+  +D++c   +  Yl L  LS++
  EEA21204.1  65 DCRDPNSRIVCRPNDSRCLTSNREYLNLQPLSKS 98 
                 5567788999999***************999975 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 1.9e-05
                 HHHT--TT......SEEEEEESS-----SHHHHHH...HHHHHHTTSS-TT CS
     THDPS_N 112 lkkaleeeskqkekeyrlvvlyeDkackSvesvYl...KLlaLSlgkaplR 159
                 + ++++e  ++++ + ++ v+y+D++  S++ + l   +LlaLS +k p+R
  EEA21204.1 155 VITIATEIRMRTNGDVSFEVIYDDTEGVSLKGMSLlkkQLLALSNNKLPIR 205
                 33344444566778888999**********998765545**********99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (212 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       406  (0.0226449); expected 358.6 (0.02)
Passed bias filter:                      359  (0.0200234); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 1444.58
//
Query:       EEA21205.1  [L=775]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.3e-11   44.4   0.3    1.2e-05   25.3   0.0    3.4  4  LysM         LysM domain
    4.9e-11   43.1   0.6    2.5e-06   27.7   0.0    2.6  2  DUF1080      Domain of Unknown Function (DUF1080)
     0.0016   19.0   0.1        1.7    9.3   0.1    2.6  2  Laminin_G_2  Laminin G domain
  ------ inclusion threshold ------
      0.042   14.0   6.4       0.19   11.9   0.3    2.9  2  Laminin_G_3  Concanavalin A-like lectin/glucanases superfamil


Domain annotation for each model (and alignments):
>> LysM  LysM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.3   0.0   2.6e-09   1.2e-05       1      44 []     238     283 ..     238     283 .. 0.92
   2 ?   -2.3   0.0       1.1     5e+03       1      33 [.     290     325 ..     290     332 .. 0.72
   3 !   15.1   0.0   3.9e-06     0.017       1      37 [.     391     431 ..     391     437 .. 0.84
   4 ?   -1.9   0.1      0.79   3.5e+03      25      39 ..     728     744 ..     727     745 .. 0.73

  Alignments for each domain:
  == domain 1  score: 25.3 bits;  conditional E-value: 2.6e-09
                 EEE-TT--HHHHHHHCTCHHHHHHHHC..TCSSCGG--TTEEEEEE CS
        LysM   1 YtVkkGDTLwsIAkrygitveklleaN..nlsspdkifpGqkLkiP 44 
                 Yt++ GDT+ sIA +y++t   +l  N   ++++  + pG +++ P
  EEA21205.1 238 YTIQAGDTCDSIAIAYNVTSASILTNNpmFVNNCSSLIPGNTICMP 283
                 9****************************6666666********98 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1.1
                 EEE-TT--HHHHHHHCTCHHHHHHHHC...TCSSCG CS
        LysM   1 YtVkkGDTLwsIAkrygitveklleaN...nlsspd 33 
                 Yt ++ D + ++  ++g+   +l+++N   n  +++
  EEA21205.1 290 YTLQPDDDCMTVEWKNGLRDGTLRQYNpciNYFCDN 325
                 888888888888888888888899999877443333 PP

  == domain 3  score: 15.1 bits;  conditional E-value: 3.9e-06
                 EEE-TT--HHHHHHHCTCHHHHHHHHC.TCSSCG...G--T CS
        LysM   1 YtVkkGDTLwsIAkrygitveklleaN.nlsspd...kifp 37 
                 YtV +GDT+ +I +  +i+ + +l++N  l+s++   ++ +
  EEA21205.1 391 YTVNEGDTCAQICSMESIPSSLFLACNpTLNSTNcdaNLVV 431
                 9***************************7777664446555 PP

  == domain 4  score: -1.9 bits;  conditional E-value: 0.79
                 HHC...TCSSCGG--TTE CS
        LysM  25 eaN...nlsspdkifpGq 39 
                 ++N   +++  d i +Gq
  EEA21205.1 728 NWNeikRVDAAD-INAGQ 744
                 799666666777.99999 PP

>> DUF1080  Domain of Unknown Function (DUF1080)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.7   0.0   5.6e-10   2.5e-06      10     183 ..     469     624 ..     458     626 .. 0.81
   2 !   13.1   0.1   1.7e-05     0.074      13     153 ..     641     769 ..     630     775 .] 0.74

  Alignments for each domain:
  == domain 1  score: 27.7 bits;  conditional E-value: 5.6e-10
                 TTTTEEETTSSS..TTEEEETTEEE.CGG.ESSS--EEESSEBSSEEEEEEEEE.ETTTEEEEEEEESCTTTSSGGGTSCEEEEE-TTTHSTCCCSTTS CS
     DUF1080  10 dldgWkgkegkatseatkvedGvlvaaessgkgggflitkkefgdfeLklefki.seggnSGillrsqkeekgkdavagyevqildsekekganrstGs 107
                 ++++W +++g+          G+lv    s++ gg  + + ++g+f  ++++ + s++gn+G+ +r++++  g da++gy + i  s+      +++ +
  EEA21205.1 469 SMAQWMTYDGSFGA-----SSGALV---GSNSFGGKALINSNYGNFLYEVDVTLpSASGNAGLVFRVTNPSVGADAYNGYYAGISTSSVF---VGRASN 556
                 67788888555543.....489999...6777777777788************866688***************************8877...222222 PP

                 BTTTBTTB--SSS--S--TTSEEEEEEEEETTEEEEEETTEEEEEEETTSHHHHHHSSBEEEEECCCSTEEEEEEE CS
     DUF1080 108 lydeeskqvkpkakaakppgeWntyeiivkgdrvtvwlNGvlvldftdldaetekgkkgpIaLqdhgaeveFRnik 183
                  +         +a+++  +++ ++++++v++ ++ +++++   + +  +d+++   ++g  ++ + g e+ F ni+
  EEA21205.1 557 SW-----TPLGSAQVDLAINQLHHVKVEVVDTTLNIFVDDMNKVLVSVTDGTY---TSGMNGVRVYGTEATFDNIQ 624
                 22.....2336799*************************98877777777766...99999999999999999997 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 1.7e-05
                 TEEETTSSS..TTEEEETTEEE.CGG.ESSS--EEESS.EBSSEEEEEEEEE..ETTTEEEEEEEESCTTTSSGGGTSCEEEEE-TTTHSTCCCSTTSB CS
     DUF1080  13 gWkgkegkatseatkvedGvlvaaessgkgggflitkk.efgdfeLklefki..seggnSGillrsqkeekgkdavagyevqildsekekganrstGsl 108
                 +W++++g++     +v  +v v    ++++ +  +t+     d + ++e+ i  +++gn G+++r+ + + g d ++gy v i  ++      + + + 
  EEA21205.1 641 KWTTIDGQY-----QVSSNVAV---LTASPAAKAVTTGvTSADIIYEAEISInsTPNGNGGMIFRVSNAAPGADTYNGYYVGIGIGYVV---FGFADTN 728
                 455553332.....23344444...44555555555543889*********9999999*************************998877...5555555 PP

                 TTTBTTB--SSS--S--TTSEEEEEEEEETTEEEEEETTEEEEEE CS
     DUF1080 109 ydeeskqvkpkakaakppgeWntyeiivkgdrvtvwlNGvlvldf 153
                 +    ++ k ++ a++++g+  ++ i   gd++++++++  + ++
  EEA21205.1 729 W----NEIKRVDAADINAGQIYHLAIQTSGDSISIFVDDLNTPRM 769
                 5....4445889999999999999999999999999988766555 PP

>> Laminin_G_2  Laminin G domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.1   0.00037       1.7      47      77 ..     565     595 ..     544     611 .. 0.81
   2 !    6.8   0.0    0.0021       9.4       8      76 ..     693     766 ..     687     773 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00037
                  SSS-ESSSSEEEEEEECTTEEEEEECTS--C CS
  Laminin_G_2  47 gkklndgewHsveverkgknltlsvDggets 77 
                  + +l+ ++ H+v+ve+ +++l++ vD+ +++
   EEA21205.1 565 QVDLAINQLHHVKVEVVDTTLNIFVDDMNKV 595
                  778999********************98765 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.0021
                  EEEEEEEE.....STTEEEEEEEETTEEEEEEESSS-EEEEE-SSSS-ESSSSEEEEEEECTTEEEEEECTS-- CS
  Laminin_G_2   8 GlLlyagd.....eksdflalelkdgklvltynlgsgdtellssgkklndgewHsveverkgknltlsvDgget 76 
                  G+++++++     ++ +  ++ +  g++v+ +   + ++  ++  +++n g+  ++ ++++g ++++ vD+ +t
   EEA21205.1 693 GMIFRVSNaapgaDTYNGYYVGIGIGYVVFGFADTNWNEIKRVDAADINAGQIYHLAIQTSGDSISIFVDDLNT 766
                  5566666666655444456777777888888877666666667799************************9875 PP

>> Laminin_G_3  Concanavalin A-like lectin/glucanases superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.7     0.012        52      30      99 ..     517     590 ..     512     625 .. 0.67
   2 ?   11.9   0.3   4.1e-05      0.19      18      99 ..     675     762 ..     658     766 .. 0.74

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.012
  Laminin_G_3  30 lpsaaqiiis....sssdgrgfelgldgsgrlrfsvnagngaee.svtsgasvpageWtHvavtydggtlrlYvN 99 
                  ++++a+++++    s +++  ++ +++g  + ++ v+ + ++++   ++  +++ ++ +Hv v + ++tl+++v+
   EEA21205.1 517 ASGNAGLVFRvtnpSVGAD-AYNGYYAGISTSSVFVGRASNSWTpLGSAQVDLAINQLHHVKVEVVDTTLNIFVD 590
                  5555666666554422223.44444443333333333333345515556669999******************98 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 4.1e-05
  Laminin_G_3  18 sfTvsaWvkpdslpsaaqiiis......sssdg....rgfelgldgsgrlrfsvnagngaeesvtsgasvpageWtHvavtydggtlrlYvN 99 
                  ++ ++a + ++s+p+ ++ +i+          g    +g+++g+ g g++ f ++++n +e +   +a+++ag+ +H+a+  +g++++++v+
   EEA21205.1 675 DIIYEAEISINSTPNGNGGMIFrvsnaaP---GadtyNGYYVGI-GIGYVVFGFADTNWNEIKRVDAADINAGQIYHLAIQTSGDSISIFVD 762
                  55566777788887776665555654431...142344666666.557999999999966667779*************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (775 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       509  (0.0283898); expected 358.6 (0.02)
Passed bias filter:                      343  (0.019131); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.67u 0.25s 00:00:00.92 Elapsed: 00:00:00.46
# Mc/sec: 5088.27
//
Query:       EEA21206.1  [L=244]
Description: hypothetical protein PMAA_050240 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (244 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       533  (0.0297284); expected 358.6 (0.02)
Passed bias filter:                      405  (0.0225891); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.41u 0.23s 00:00:00.64 Elapsed: 00:00:00.36
# Mc/sec: 2027.62
//
Query:       EEA21207.1  [L=274]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-22   80.3   1.1    2.5e-22   79.4   0.2    1.9  2  OrsD      Orsellinic acid/F9775 biosynthesis cluster protein 


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.4   0.2   1.4e-26   2.5e-22       3     114 .]      12     119 ..      10     119 .. 0.91
   2 ?   -1.8   0.1      0.22     4e+03      45      55 ..     133     142 ..     122     177 .. 0.56

  Alignments for each domain:
  == domain 1  score: 79.4 bits;  conditional E-value: 1.4e-26
        OrsD   3 feyneeyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgLpvy.eGyrC.rakakCkylt 99 
                 fe+  ++ v+iCreC+y+v+ps++e HL++ h++++   + +l  +v      r++ ++a ++ ++++p++  + ip+L    +G +C   +++C y++
  EEA21207.1  12 FERLVDFPVVICRECQYGVWPSQIEGHLQRAHQHISPMIRIQLGDEV------RSWPNIAIDPIELEIPPTRTQAIPQLIGPlDGWQCqLSPQSCVYIC 104
                 78888999*********************888888777677788888......*************************98766*****778899***** PP

        OrsD 100 rslktlrkHlqkkhg 114
                 +s++++r+H+ ++hg
  EEA21207.1 105 QSINAMRNHWYNQHG 119
                 ***********9995 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.22
        OrsD  45 lletvehemsl 55 
                  ++t+ +e+++
  EEA21207.1 133 TMQTI-QEQQK 142
                 33333.11111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (274 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       551  (0.0307323); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.23s 00:00:00.62 Elapsed: 00:00:00.36
# Mc/sec: 2259.81
//
Query:       EEA21208.1  [L=1520]
Description: DNA helicase recq, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.6e-19   69.7   0.0      1e-18   67.8   0.0    2.1  1  OrsD        Orsellinic acid/F9775 biosynthesis cluster protei
    8.9e-14   51.6   0.1    2.5e-13   50.2   0.1    1.8  1  DEAD        DEAD/DEAH box helicase
    3.7e-12   46.6   0.0    1.5e-11   44.6   0.0    2.1  2  Helicase_C  Helicase conserved C-terminal domain
    1.7e-05   24.9   0.0    5.6e-05   23.2   0.0    1.9  2  ResIII      Type III restriction enzyme, res subunit
     0.0092   15.7   0.5        3.1    7.5   0.1    3.0  3  AAA_30      AAA domain


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.8   0.0   2.9e-22     1e-18       3     114 .]      12     119 ..      10     119 .. 0.93

  Alignments for each domain:
  == domain 1  score: 67.8 bits;  conditional E-value: 2.9e-22
        OrsD   3 feyneeyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgLpvy.eGyrC.rakakCkylt 99 
                 fe+  ++ v+iCreC+y+v+ps++e HL++ hr ++   + +l  +v      r + e+a ++ ++++p+  s+ ip+L    +G +C   + +C y++
  EEA21208.1  12 FERLVDFPVVICRECQYGVWPSQIEGHLQHAHRYISPVIRIQLGDEV------RGWPEIAIDPIELDIPPIRSQAIPQLIGPlDGWQCqLSPGSCLYVC 104
                 78888999*********************999999888888899999......*************************98766*****778889***** PP

        OrsD 100 rslktlrkHlqkkhg 114
                  s++t+r+H+ k+hg
  EEA21208.1 105 PSISTMRQHWFKQHG 119
                 ***********9995 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.2   0.1     7e-17   2.5e-13       3     174 ..     961    1113 ..     959    1115 .. 0.77

  Alignments for each domain:
  == domain 1  score: 50.2 bits;  conditional E-value: 7e-17
                  HHHHHHHHHHTTC.EEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTC CS
                  xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD    3 iQaeaiplilggg.dvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngv 98  
                   Q+++i+ i++ +  +++ ++TG+GK+l f++p+         ++g  +++v+P+ +L  +  +++++++         +++ +++    +    g+
  EEA21208.1  961 TQKAVIQSIVQRQsPIVAIMPTGAGKSLLFMLPAW-------MSRGGTTIVVVPLVALRVDLQQRCQTLGIS-------CVEWDSR----RPA-DGA 1038
                  599*******766378899****************.......4677899*************9999999994.......2444444....444.788 PP

                  SEEEEEHHHHHHHH.....HCTSSHCTTEEEEEEETHHHHHHT..TTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHHH CS
                  xxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   99 divvgtpgrlddll.....stgklnlsqvrflVlDEadrlldq..gfsdfinrilnqlpqitcdgklqrqvivlSATlpkdvk 174 
                   iv+ tp+  ++ +     + +k  ++++  +V+DE++ +l++  +f++++ ++ +         +++ q+++l+ATlp+d +
  EEA21208.1 1039 AIVLVTPESAMSETfqtfiN-RKQWTKELDRIVIDECHIILQEgyQFRKQMAQLGAL-------VRAETQLVLLTATLPRDRE 1113
                  9******9999966466533.343599****************44444555553333.......345567*********8866 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.6   0.0   4.3e-15   1.5e-11      14     110 ..    1170    1259 ..    1157    1260 .. 0.90
   2 ?   -3.9   0.0         5   1.8e+04      68      83 ..    1504    1519 ..    1496    1519 .. 0.80

  Alignments for each domain:
  == domain 1  score: 44.6 bits;  conditional E-value: 4.3e-15
                  TTTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSSHHHHHHHHTTSSST CS
  Helicase_C   14 eeggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprnvtsyiqriGRtgRa 110 
                   ++gk++i++nti ++   + +   +++++ ++++  ++ +++ +l++f+k++  v++at+++++Gidi +++lVi+ +  r++ +y q +GR+gR 
  EEA21208.1 1170 LHEGKVVIYANTIATV---QQI--AHQLQCPAYYS--EAVDKKGMLASFRKQNPGVIVATSALGMGIDIADIRLVIHEGRTRSLLDYGQESGRAGRD 1259
                  5789************...566..46789999999..8999********998888*****************************************6 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 5
                  SEEEESGGGTSSSTST CS
  Helicase_C   68 dvLiatdvaerGidip 83  
                  + ++at  a+ G++ip
  EEA21208.1 1504 TGMVATGRASSGVNIP 1519
                  5579999999999997 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.2   0.0   1.6e-08   5.6e-05       7     170 ..     961    1109 ..     945    1110 .. 0.78
   2 ?   -4.1   0.0       3.9   1.4e+04      43      75 ..    1161    1193 ..    1159    1210 .. 0.70

  Alignments for each domain:
  == domain 1  score: 23.2 bits;  conditional E-value: 1.6e-08
                  HHHHHHHHHT......TTSEEEEEESTTSTHHHHHHHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--....... CS
      ResIII    7 yQeeaienlleklkskrdkrglikmaTGtGKTlvaaklierllkkgkeekflflvprkslleqtleefkkflseaykeigkkvsgdkkkakekdstn 103 
                   Q+ +i++++     +r+  ++  m+TG+GK+l+ +  ++  +       ++++vp  +l   ++++ + +  +++     ++  d++++    ++ 
  EEA21208.1  961 TQKAVIQSIV-----QRQSPIVAIMPTGAGKSLLFMLPAWMSRGG----TTIVVVPLVALRVDLQQRCQTLGISCV-----EW--DSRRP----ADG 1037
                  5555555555.....8999**************999999988875....89*********************9984.....44..44455....559 PP

                  -SEEEEEHHHHHHTH........HHHTTT-SEEEEETGGGTTS......TTTHHHHHT-.--SEEEEEESS-S CS
      ResIII  104 kkilvttiqsldadseeeeeeseellrdrfdviiiDEaHrlgak.....kswreilekf.keavllglTATpe 170 
                  + i+++t +s+ ++   ++  + ++  ++ d i+iDE+H + ++     k++ ++   +  e  l+ lTAT++
  EEA21208.1 1038 AAIVLVTPESAMSET-FQTFINRKQWTKELDRIVIDECHIILQEgyqfrKQMAQLGALVrAETQLVLLTATLP 1109
                  999999999999998.4456666667777779*******9999655555566666333324477778899986 PP

  == domain 2  score: -4.1 bits;  conditional E-value: 3.9
                  HHHHHH-S.....-EEEEESSHHHHHHHHHHGG CS
      ResIII   43 klierllkkgkeekflflvprkslleqtleefk 75  
                  + i++  +  +e k+++ +++++ ++q  ++++
  EEA21208.1 1161 AWIQQRVQPLHEGKVVIYANTIATVQQIAHQLQ 1193
                  556666666677788888888888888776654 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.9   0.0    0.0055        20     152     187 ..     185     220 ..     176     224 .. 0.90
   2 !    7.5   0.1   0.00085       3.1       3     114 ..     959    1097 ..     957    1105 .. 0.69
   3 ?   -1.7   0.0      0.55     2e+03      46      71 ..    1172    1197 ..    1158    1212 .. 0.79

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.0055
      AAA_30 152 tevvRqkeseeraaalalregdaeealealadrgri 187
                 ++  Rq  + e++aa+++++g+++ea  +l++ g++
  EEA21208.1 185 EQASRQYAEYEKQAAERIQQGHVDEANPWLRRTGWV 220
                 57789999***********************99998 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.00085
      AAA_30    3 naeQaaavealltsgdrvavltGpAGtGKttalkalreaweaaggrviglAptgkaAkvLaeelgieastiakllkrlk.................. 81  
                  +  Q+a+++++++ +    v+  p G+GK+ +   +  aw ++gg+ i++ p  +   +L++ +++ + +  ++ +r                    
  EEA21208.1  959 RGTQKAVIQSIVQRQS-PIVAIMPTGAGKSLLF--MLPAWMSRGGTTIVVVPLVALRVDLQQRCQTLGISCVEWDSRRPadgaaivlvtpesamset 1052
                  568******9999997.7777789*****9887..56789999999999999999999999755542222222222222344555555556888888 PP

      AAA_30   82 .....grarlepg.tllivDEagmv......dtkqlaallkaaek 114 
                       +r++++++ + +++DE   +        kq+a+l + +++
  EEA21208.1 1053 fqtfiNRKQWTKElDRIVIDECHIIlqegyqFRKQMAQLGALVRA 1097
                  88888778999999*******987755554444566666666655 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 0.55
      AAA_30   46 ggrviglAptgkaAkvLaeelgieas 71  
                  +g+v+++A t +  +++a++l+ +a+
  EEA21208.1 1172 EGKVVIYANTIATVQQIAHQLQCPAY 1197
                  589**************999998775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1520 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       703  (0.0392102); expected 358.6 (0.02)
Passed bias filter:                      497  (0.0277205); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.89u 0.30s 00:00:01.19 Elapsed: 00:00:00.46
# Mc/sec: 9905.40
//
Query:       EEA21209.1  [L=686]
Description: hypothetical protein PMAA_050270 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      1e-09   38.8   1.4    1.7e-09   38.1   0.2    2.0  2  OrsD        Orsellinic acid/F9775 biosynthesis cluster protei
     0.0035   16.9   0.1      0.093   12.3   0.0    3.0  3  zf-C2H2_12  Zinc-finger C2H2-type
  ------ inclusion threshold ------
      0.047   13.7   0.9      0.047   13.7   0.9    2.5  3  zf-BED      BED zinc finger
        1.6    9.7   3.9        2.3    9.3   0.7    3.0  2  zf-C2H2_4   C2H2-type zinc finger


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.1   0.2   3.7e-13   1.7e-09       8     114 .]      21     116 ..      17     116 .. 0.89
   2 ?   -3.2   0.1       2.4   1.1e+04      26      58 ..     168     200 ..     159     204 .. 0.55

  Alignments for each domain:
  == domain 1  score: 38.1 bits;  conditional E-value: 3.7e-13
        OrsD   8 eyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgLpvyeGyrCrakakC.kyltrslktl 105
                 ++r+liC++C +a+ p+++++H  ++h+    e+++ l e++      rq d   +e++ v +++      p L +y+G+ C     C +y t +l++l
  EEA21209.1  21 NFRLLICESCGFALGPNQASSHFWEKHQVS-VEQRHGLTEYL------RQHD--FQEPASVAPRPRGASEHPALRTYNGLAC---RLCeTYYTINLDNL 107
                 5799********************998887.666899**999......8888..789999999999999999**********...56736********* PP

        OrsD 106 rkHlqkkhg 114
                  kHl+++h+
  EEA21209.1 108 LKHLRHQHP 116
                 ******995 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.4
        OrsD  26 lerHLrkrhrqlkrektqelletvehemslrql 58 
                 l++  r+rh  ++ +++q    ++  ++slr++
  EEA21209.1 168 LQERERTRHAAIQAATVQDSGIATRSFESLRPW 200
                 444445566666555555555555455555555 PP

>> zf-C2H2_12  Zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0       0.1   4.5e+02      19      38 ..      21      40 ..      14      65 .. 0.67
   2 !   12.3   0.0   2.1e-05     0.093      21      55 ..      89     122 ..      86     133 .. 0.85
   3 ?   -3.9   0.0       2.4   1.1e+04      11      20 ..     544     553 ..     540     562 .. 0.78

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.1
  zf-C2H2_12 19 qrrglvCmvCgeslaslkls 38
                + r l+C  Cg +l   + s
  EEA21209.1 21 NFRLLICESCGFALGPNQAS 40
                56789*****9998766554 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 2.1e-05
  zf-C2H2_12  21 rglvCmvCgeslaslklstikrHIrqvHPeslsls 55 
                 +gl C  C+ + ++++l+++ +H r++HP+  + s
  EEA21209.1  89 NGLACRLCE-TYYTINLDNLLKHLRHQHPDRPRSS 122
                 79******7.579****************976655 PP

  == domain 3  score: -3.9 bits;  conditional E-value: 2.4
  zf-C2H2_12  11 eyLmdydpqr 20 
                 + L+dy+p+ 
  EEA21209.1 544 DLLLDYHPSI 553
                 6799999875 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0      0.56   2.5e+03      19      43 ..      27      47 ..      25      48 .. 0.60
   2 ?   -3.5   0.1       2.5   1.1e+04      28      38 ..      54      64 ..      53      64 .. 0.84
   3 ?   13.7   0.9   1.1e-05     0.047      17      44 .]      91     116 ..      80     116 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.56
                ETTTTEE----SSTHHHHHHHHHS- CS
      zf-BED 19 CryCgkilsrgggttnLkrHLrrkH 43
                C  Cg+ l    g +  ++H + kH
  EEA21209.1 27 CESCGFAL----GPNQASSHFWEKH 47
                66677665....4556666666666 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 2.5
                --SSTHHHHHH CS
      zf-BED 28 rgggttnLkrH 38
                r+g t +L++H
  EEA21209.1 54 RHGLTEYLRQH 64
                667899****9 PP

  == domain 3  score: 13.7 bits;  conditional E-value: 1.1e-05
                 -EETTTTEE----SSTHHHHHHHHHS-H CS
      zf-BED  17 avCryCgkilsrgggttnLkrHLrrkHp 44 
                   Cr C+  ++   +  nL +HLr++Hp
  EEA21209.1  91 LACRLCETYYTI--NLDNLLKHLRHQHP 116
                 57**********..8************8 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.1      0.84   3.8e+03       2      20 ..      26      43 ..      25      47 .. 0.62
   2 ?    9.3   0.7   0.00052       2.3       2      24 .]      92     115 ..      91     115 .. 0.91

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.84
   zf-C2H2_4  2 kCpiCgksFs.skkaLlrHl 20
                +C+ C   F   +++ ++H+
  EEA21209.1 26 ICESC--GFAlGPNQASSHF 43
                7999*..6654555555665 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.00052
   zf-C2H2_4   2 kCpiCgksFs.skkaLlrHlkthH 24 
                  C++C + ++ + ++Ll+Hl+ +H
  EEA21209.1  92 ACRLCETYYTiNLDNLLKHLRHQH 115
                 6********988888******999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (686 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       508  (0.028334); expected 358.6 (0.02)
Passed bias filter:                      405  (0.0225891); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.48
# Mc/sec: 4288.15
//
Query:       EEA21210.1  [L=103]
Description: hypothetical protein PMAA_050280, partial [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (103 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       415  (0.0231469); expected 358.6 (0.02)
Passed bias filter:                      352  (0.019633); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.27s 00:00:00.69 Elapsed: 00:00:00.44
# Mc/sec: 696.52
//
Query:       EEA21211.1  [L=118]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (118 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       632  (0.0352502); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 850.06
//
Query:       EEA21212.1  [L=252]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.1e-28   96.6   4.1    6.1e-08   32.8   0.1    4.3  4  Ank       Ankyrin repeat
    9.2e-27   93.5   0.2      1e-12   48.5   0.0    2.3  2  Ank_2     Ankyrin repeats (3 copies)
    1.2e-25   89.2   0.8    2.8e-11   43.4   0.1    3.3  3  Ank_5     Ankyrin repeats (many copies)
      9e-22   74.8   0.8    0.00016   21.9   0.0    4.4  4  Ank_3     Ankyrin repeat
      9e-17   61.2   1.0    1.6e-07   31.7   0.0    4.1  4  Ank_4     Ankyrin repeats (many copies)


Domain annotation for each model (and alignments):
>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.8   0.1   1.7e-11   6.1e-08       1      31 [.      78     107 ..      78     108 .. 0.96
   2 !   23.4   0.0   1.5e-08   5.5e-05       1      31 [.     112     143 ..     112     144 .. 0.83
   3 !   19.4   0.8   2.9e-07     0.001       1      23 [.     145     169 ..     145     178 .. 0.86
   4 !   19.0   0.0     4e-07    0.0014       2      27 ..     182     208 ..     181     211 .. 0.93

  Alignments for each domain:
  == domain 1  score: 32.8 bits;  conditional E-value: 1.7e-11
                 TSBBHHHHHHHHTTHHHHHHHHTTTSTTCBT CS
         Ank   1 dGnTPLHlAatngkkriiklLLhGAnlnald 31 
                 +G+T+LHlAa+ gk+++i+lLL +A++ a+d
  EEA21212.1  78 NGFTALHLAAYLGKASVIRLLL-SACPEAVD 107
                 8*********************.******99 PP

  == domain 2  score: 23.4 bits;  conditional E-value: 1.5e-08
                 TSBBHHHHHHHHTT.HHHHHHHH.TTTSTTCBT CS
         Ank   1 dGnTPLHlAatngk.kriiklLL.hGAnlnald 31 
                 dG TPLH+Aa++g  + +++ LL  GAn  ++d
  EEA21212.1 112 DGETPLHIAASEGRfEAVVE-LLrAGANTLLQD 143
                 8*********8888666777.7758***98888 PP

  == domain 3  score: 19.4 bits;  conditional E-value: 2.9e-07
                 TSBBHHHHHHHHTTHHHHHHHH..T CS
         Ank   1 dGnTPLHlAatngkkriiklLL..h 23 
                 dG+T+LH+A++  +++ ++lLL  h
  EEA21212.1 145 DGHTVLHVAVCKEHVNLVHLLLdgH 169
                 8*********9***********552 PP

  == domain 4  score: 19.0 bits;  conditional E-value: 4e-07
                 SBBHHHHHHHHTTHHHHHHHH.TTTST CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnl 27 
                 G TPLH A+  g  +i++ +L +GA++
  EEA21212.1 182 GKTPLHQAVLQGCDQIVQIFLaKGADP 208
                 99*******9999********99***8 PP

>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.5   0.0   2.8e-16     1e-12      23      81 ..      73     141 ..      55     143 .. 0.82
   2 !   44.2   0.1   6.2e-15   2.2e-11      20      82 ..     142     211 ..     136     212 .. 0.85

  Alignments for each domain:
  == domain 1  score: 48.5 bits;  conditional E-value: 2.8e-16
       Ank_2  23 n.k..ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlekgadinl 81 
                 n +  ng taLh+Aa  g+  +++lLl++       +++dg+tpLh+Aa++g++e+v  Ll  ga+  l
  EEA21212.1  73 NsNrlNGFTALHLAAYLGKASVIRLLLSAcpeavdvTNSDGETPLHIAASEGRFEAVVELLRAGANTLL 141
                 232579************9999*****9667786766699*********************88998665 PP

  == domain 2  score: 44.2 bits;  conditional E-value: 6.2e-15
       Ank_2  20 adpnkngktaLhyAakngnleivklLle.h........adndgrtpLhyAarsghleivklLlekgadinlk 82 
                  d+  +g+t+Lh+A+ + ++++v lLl+ h         d+ g+tpLh A+ +g  +iv+++l kgad+ ++
  EEA21212.1 142 QDV--DGHTVLHVAVCKEHVNLVHLLLDgHhgqtlirlSDSAGKTPLHQAVLQGCDQIVQIFLAKGADPRMT 211
                 344..59********************973587887766689*********************9****9875 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.5   0.1   2.1e-11   7.6e-08       8      52 ..      71     116 ..      69     116 .. 0.95
   2 !   43.4   0.1   7.8e-15   2.8e-11       1      56 []      98     153 ..      98     153 .. 0.98
   3 !   24.1   0.0   8.8e-09   3.1e-05       9      45 ..     175     211 ..     169     211 .. 0.87

  Alignments for each domain:
  == domain 1  score: 32.5 bits;  conditional E-value: 2.1e-11
       Ank_5   8 dvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGlta 52 
                 ++n ++ +g+t+Lh+Aa+ g a+v+rlLl a +++ ++t+s+G+t+
  EEA21212.1  71 STNSNRLNGFTALHLAAYLGKASVIRLLLsACPEAVDVTNSDGETP 116
                 6788999999***********************************8 PP

  == domain 2  score: 43.4 bits;  conditional E-value: 7.8e-15
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 Ll+++p++v+ ++ +g+tpLh+Aa+ g+++ v +Ll  ga++ l+d +G t+l++A
  EEA21212.1  98 LLSACPEAVDVTNSDGETPLHIAASEGRFEAVVELLRAGANTLLQDVDGHTVLHVA 153
                 89999*************************************************98 PP

  == domain 3  score: 24.1 bits;  conditional E-value: 8.8e-09
       Ank_5   9 vnrldgggntpLhvAakygaadvvrlLlargadlnlt 45 
                 +  +d  g tpLh+A+ +g+ ++v+++la gad+++t
  EEA21212.1 175 IRLSDSAGKTPLHQAVLQGCDQIVQIFLAKGADPRMT 211
                 556788888*************************986 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   3.6e-06     0.013       1      27 [.      78     104 ..      78     108 .. 0.87
   2 !   21.9   0.0   4.3e-08   0.00016       1      28 [.     112     138 ..     112     140 .. 0.91
   3 !   13.1   0.1   3.2e-05      0.11       1      26 [.     145     171 ..     145     174 .. 0.90
   4 !   19.3   0.0     3e-07    0.0011       2      30 ..     182     209 ..     181     210 .. 0.94

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 3.6e-06
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkga 27 
                 nG t+LhlAa  g+ +++++Ll  +  
  EEA21212.1  78 NGFTALHLAAYLGKASVIRLLLSACPE 104
                 799*******************96655 PP

  == domain 2  score: 21.9 bits;  conditional E-value: 4.3e-08
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgad 28 
                 +GetpLh+Aa+ g++e v  Ll+  ga+
  EEA21212.1 112 DGETPLHIAASEGRFEAVVELLR-AGAN 138
                 69**************9999999.7876 PP

  == domain 3  score: 13.1 bits;  conditional E-value: 3.2e-05
       Ank_3   1 nGetpLhlAarsgnleivkfLle.nkg 26 
                 +G t Lh+A+   ++++v++Ll+ ++g
  EEA21212.1 145 DGHTVLHVAVCKEHVNLVHLLLDgHHG 171
                 699********************6665 PP

  == domain 4  score: 19.3 bits;  conditional E-value: 3e-07
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G tpLh+A+++g+  iv+ +l  kgad++
  EEA21212.1 182 GKTPLHQAVLQGCDQIVQIFLA-KGADPR 209
                 89********************.9***97 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.9   0.1   7.3e-05      0.26      34      55 .]      78      99 ..      69      99 .. 0.87
   2 !   31.7   0.0   4.5e-11   1.6e-07       3      53 ..      81     131 ..      79     134 .. 0.88
   3 !   20.7   0.2   1.3e-07   0.00047       2      46 ..     147     193 ..     146     193 .. 0.89
   4 !   15.3   0.0   6.3e-06     0.023       3      30 ..     184     211 ..     182     220 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 7.3e-05
       Ank_4 34 sGetalhiAakrgnveilklLl 55
                +G+talh Aa+ g+ ++++lLl
  EEA21212.1 78 NGFTALHLAAYLGKASVIRLLL 99
                7******************997 PP

  == domain 2  score: 31.7 bits;  conditional E-value: 4.5e-11
       Ank_4   3 taLhyaaisgrlelvrlLlekgad.inaqdnrsGetalhiAakrgnveilkl 53 
                 taLh aa+ g+  ++rlLl+  ++ ++ + n++Get+lhiAa+ g++e++  
  EEA21212.1  81 TALHLAAYLGKASVIRLLLSACPEaVDVT-NSDGETPLHIAASEGRFEAVVE 131
                 79*****************8866668888.***************9888754 PP

  == domain 3  score: 20.7 bits;  conditional E-value: 1.3e-07
       Ank_4   2 ltaLhyaaisgrlelvrlLl..ekgadinaqdnrsGetalhiAakrg 46 
                 +t+Lh a+ ++++ lv+lLl   +g+ + + +++ G t+lh A++ g
  EEA21212.1 147 HTVLHVAVCKEHVNLVHLLLdgHHGQTLIRLSDSAGKTPLHQAVLQG 193
                 79******************544799999999***********9865 PP

  == domain 4  score: 15.3 bits;  conditional E-value: 6.3e-06
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaq 30 
                 t+Lh+a+ +g+ ++v++ l+kgad+ ++
  EEA21212.1 184 TPLHQAVLQGCDQIVQIFLAKGADPRMT 211
                 89**********************9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (252 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       357  (0.0199119); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1855.78
//
Query:       EEA21213.1  [L=1395]
Description: oligomycin resistance ATP-dependent permease yor1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.4e-53  179.9  29.2    1.4e-29  103.6  13.9    3.4  3  ABC_membrane  ABC transporter transmembrane region
      2e-49  167.6   0.0    4.1e-26   92.1   0.0    2.6  2  ABC_tran      ABC transporter
    1.3e-07   31.7   0.6      0.024   14.7   0.1    2.8  2  MMR_HSR1      50S ribosome-binding GTPase
    3.1e-07   30.5   1.6       0.26   11.1   0.0    4.2  4  AAA_21        AAA domain, putative AbiEii toxin, Type IV TA s
    6.3e-07   29.7   3.8    0.00053   20.2   0.3    2.6  2  DUF87         Helicase HerA, central domain
    1.7e-06   28.6   0.2      0.011   16.2   0.1    2.6  2  AAA_16        AAA ATPase domain
    5.9e-06   25.9   1.9      0.038   13.7   0.6    2.7  2  AAA_29        P-loop containing region of AAA domain
      6e-05   22.6   4.8        1.5    8.2   0.1    3.7  4  SMC_N         RecF/RecN/SMC N terminal domain
    0.00043   20.2   2.6       0.58   10.0   0.1    2.4  2  RsgA_GTPase   RsgA GTPase
    0.00061   19.4   0.2       0.32   10.5   0.0    2.4  2  AAA_7         P-loop containing dynein motor region
    0.00066   20.2   0.2        1.7    9.1   0.1    2.7  2  AAA_23        AAA domain
     0.0012   18.2   1.1       0.49    9.7   0.0    2.4  2  FtsK_SpoIIIE  FtsK/SpoIIIE family
     0.0091   15.2   0.5       0.32   10.1   0.0    2.3  2  DUF815        Protein of unknown function (DUF815)
  ------ inclusion threshold ------
      0.011   15.6   0.1        2.3    8.1   0.0    2.5  2  NACHT         NACHT domain
      0.013   14.7   1.0        2.8    7.0   0.2    3.0  2  NB-ARC        NB-ARC domain
      0.018   15.1   5.7       0.76    9.8   0.2    3.1  3  Dynamin_N     Dynamin family
      0.018   15.3   3.9        3.9    7.7   0.1    3.0  3  AAA_22        AAA domain
      0.033   13.8   1.2        6.7    6.2   0.1    2.4  2  AAA_25        AAA domain
      0.041   13.6   0.1         10    5.8   0.0    2.4  2  IstB_IS21     IstB-like ATP binding protein
       0.06   11.4   3.6      0.087   10.9   3.6    1.1  1  AF-4          AF-4 proto-oncoprotein
      0.069   12.9   0.2        6.6    6.4   0.0    2.7  3  AAA_24        AAA domain
      0.072   13.3   0.3         17    5.7   0.1    2.6  2  Roc           Ras of Complex, Roc, domain of DAPkinase
      0.096   11.6   1.6       0.39    9.6   0.1    2.2  2  AAA_10        AAA-like domain
        0.1   11.8   1.1        4.5    6.5   0.1    2.5  2  Zeta_toxin    Zeta toxin
       0.43   10.3   3.2        6.3    6.5   0.2    2.4  2  ATP_bind_1    Conserved hypothetical ATP binding protein
        3.2    7.4   4.7          4    7.1   0.2    2.5  2  AAA_15        AAA ATPase domain


Domain annotation for each model (and alignments):
>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   0.0   1.1e-06   0.00074       2      88 ..     121     217 ..     120     226 .. 0.87
   2 !   63.4   4.9   3.8e-20   2.6e-17      96     271 ..     276     449 ..     268     452 .. 0.89
   3 !  103.6  13.9   2.1e-32   1.4e-29       8     242 ..     828    1056 ..     819    1084 .. 0.89

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 1.1e-06
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSS....TCCHH...HHHHHHHHHHHHHHHHHHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHCST CS
  ABC_membrane   2 iliillailagvlsplfplvlgrildtlldk....gdpet...ealnvysllllllglaqfilallqsyll...nvtgerlskrlrrklfkkilrqp 88 
                   +++ +  ++a++l +  p+ l +++++ +d+     dpe+    a+ +   ll++++++q++++llq+++l    ++g++++  l +k+++k ++ +
    EEA21213.1 121 WIGGIYRLFADILTVGSPYTLRYLIQFAMDSyygsLDPEDgapPAVGRGVGLLIGIVVMQVLVSLLQNHFLysgQMVGGQARAILTAKILEKSMKIS 217
                   577788889999999999999999999999777555555588899**************************99999****************99876 PP

  == domain 2  score: 63.4 bits;  conditional E-value: 3.8e-20
                   CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHH CS
  ABC_membrane  96 svGellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirt 192
                   s G+++++++ dv+++++ l++ +++++ +++++v+  ++++ l+ + +l++l++l+  + + +   k + + ++  + a++ + s+++E+l+gir+
    EEA21213.1 276 SNGRVINLVSMDVHRIEECLNMVHVVWTSPIMVLVCMALLIVNLSYS-ALAGLGCLIFTMGFLIAGVKAIYTKRQGINAATDARISLTQEALQGIRV 371
                   68********************************************8.9************************************************ PP

                   HHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSTHHHHHHHHHHHHHHH CS
  ABC_membrane 193 VkafgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttlvisgelsvgdlvvflslfailf 271
                   +k+f + ++f+++  + ++e+ ++      + +++ +  q+l++l+ ++  ++ ++l + +el+   ++  ++lf+ l+
    EEA21213.1 372 IKYFSWDKNFTQRLIQIRNEETRKLQVHMAIFNAVTSLGQSLPMLLAMVS-FVTFALGSGKELTAPVVFSSVALFSALL 449
                   *************9888888877777777777777777888888887777.5555565567******999999999664 PP

  == domain 3  score: 103.6 bits;  conditional E-value: 2.1e-32
                    HHHHHHHHHHHHHHHHHHHHHHHSSTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHHHHSCHHHHHH CS
  ABC_membrane    8 ailagvlsplfplvlgrildtlldkgdpetealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsffdtnsvGells 102 
                    ++la++ ++l  l+l+ ++ + ++         n y+ ++++l+++q+ l +l s ++++tg   s+ + +k++++++r+p+ ffdt++ G++++
    EEA21213.1  828 LALAQGSNLLCGLWLAWWTLDRFG-LAR-----NTYIGIYVALTIIQGSLLYLFSLCISITGTSSSNVMLNKAIENVIRAPIWFFDTTPLGRIIN 916 
                    555555555555555555555555.444.....459*********************************************************** PP

                    HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHTT CS
  ABC_membrane  103 rltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirtVkafg 197 
                    r+++d++ ++d+l+e l lf+ s ++++g+l++++ +  +++++ll+ l+++++ + ++    +++k+ e   ++ + + + E+l g+ t++++ 
    EEA21213.1  917 RFSKDIEVMDDALPEALRLFMISAAMMIGILGLIVAYFHWFAIALLPGLVIFLFAASYYRASAHEFKRHEAMFRGVMVARFSETLAGVTTIRNYS 1011
                    ********************************999977779****************************************************** PP

                    THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane  198 reeyflekfekaleeakkagikkaianglligitqllgllsyala 242 
                    +++ f +  + a++++++ag+ +  ++++l  +++++g ++++  
    EEA21213.1 1012 MQSHFSHMLNVAIDNHNSAGFLAFSSQRWLALRLDIVGVILIVTS 1056
                    **************************************9999876 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.9   0.0     5e-23   3.5e-20       4     136 ..     540     671 ..     538     672 .. 0.85
   2 !   92.1   0.0   5.9e-29   4.1e-26       4     137 .]    1158    1298 ..    1155    1298 .. 0.93

  Alignments for each domain:
  == domain 1  score: 72.9 bits;  conditional E-value: 5e-23
                 EEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH......HHHTCHHHHHHHSTTGG CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxxx RF
    ABC_tran   4 vslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren......esdeeiekalsklglke 96 
                  s+++++ge++a++G++G+GKS+Ll++++g   +  G++             +++++++++pq++ +++++ vr+n      ++ e+ +++++  +l  
  EEA21213.1 540 FSVTVQKGELLAVIGKTGSGKSSLLSAMTGDIPKVHGSL-------------QFSSKLAFCPQTAWIQNTT-VRNNilfgtpYDPERYHAVVTACQLRT 624
                 689***********************************9.............8899********8888877.**********55555444444444444 PP

                 .......TTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 .......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  97 .......lkdtvvksspssLSgGqkqrvalarallkkpkllllDEpt 136
                         ++t +++++  LSgGqkqr+ lara+ +++k+lllD+p 
  EEA21213.1 625 dldllpkGDATEIGERGVDLSGGQKQRIGLARAIYSNQKILLLDDPL 671
                 44444445688889999****************************97 PP

  == domain 2  score: 92.1 bits;  conditional E-value: 5.9e-29
                  EEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH......HHHTCHHHHHH..HS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxx..xx RF
    ABC_tran    4 vslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren......esdeeiekals..kl 92  
                   +l +++ge vaivG++GaGKS+L++ l +  k   G il+dg d+++++le lr+++++  q++ lf+++ +r n      + dee+ +al+  +l
  EEA21213.1 1158 FNLAIEAGEHVAIVGRTGAGKSSLVSSLFRVCKLSGGCILIDGVDISKIPLEDLRSRLSIQLQDSILFRGT-IRFNldpmsqYTDEELWRALHgaHL 1253
                  6899******************************************************************9.99999****9999999999972255 PP

                  TTGGTTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran   93 glkelkdtvvksspssLSgGqkqrvalarallkkpkllllDEpta 137 
                  g++   d++v++++s++S+Gq+q +alar+l++ +k++++DE+t+
  EEA21213.1 1254 GNSVHLDDIVQEEGSNFSHGQRQQLALARILVRGRKIVVCDEATS 1298
                  555699*************************************96 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   4.5e-05     0.031       3      26 ..     551     574 ..     549     599 .. 0.87
   2 !   14.7   0.1   3.4e-05     0.024       1      21 [.    1167    1187 ..    1167    1204 .. 0.91

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 4.5e-05
                 EEEESTTSSHHHHHHHHHTSTEEE CS
    MMR_HSR1   3 aivGrpNvGKStLinaltgekaiv 26 
                 a++G++ +GKS+L++a+tg+  +v
  EEA21213.1 551 AVIGKTGSGKSSLLSAMTGDIPKV 574
                 89*****************87666 PP

  == domain 2  score: 14.7 bits;  conditional E-value: 3.4e-05
                  EEEEEESTTSSHHHHHHHHHT CS
    MMR_HSR1    1 evaivGrpNvGKStLinaltg 21  
                  +vaivGr+ +GKS+L+++l++
  EEA21213.1 1167 HVAIVGRTGAGKSSLVSSLFR 1187
                  59***************9986 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.2   0.3    0.0007      0.48       3      26 ..     551     568 ..     549     590 .. 0.77
   2 !   11.1   0.0   0.00037      0.26     236     302 ..     643     706 ..     583     707 .. 0.83
   3 ?    4.6   0.2     0.034        23       3      39 ..    1169    1200 ..    1168    1234 .. 0.73
   4 ?   -1.0   0.0       1.8   1.3e+03     236     286 ..    1269    1320 ..    1258    1323 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.0007
      AAA_21   3 vliGpNgsGKSnLLdaldllarld 26 
                 ++iG+ gsGKS+LL a+       
  EEA21213.1 551 AVIGKTGSGKSSLLSAM------T 568
                 79**************9......3 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00037
      AAA_21 236 elSdGtkrllalltallralkkgsllliDEpEngLHPkllrrll.ellkelsrngaQv.iltTHSplll 302
                 +lS G+k+ ++l+ a+++     ++ll+D+p +  +P + r ++ + + +l r  ++  il+TH+ ++l
  EEA21213.1 643 DLSGGQKQRIGLARAIYSNQ---KILLLDDPLSAVDPYVGRAIFnDAILSLLR--GKTrILATHQVHVL 706
                 45***************999...9*********************99977777..45559****99887 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.034
      AAA_21    3 vliGpNgsGKSnLLdaldllarldrdvegltdelsgg 39  
                  +++G+ g+GKS+L   l  ++ l     +++++l +g
  EEA21213.1 1169 AIVGRTGAGKSSLVSSLFRVCKL-----SGGCILIDG 1200
                  79***********9999888764.....333333333 PP

  == domain 4  score: -1.0 bits;  conditional E-value: 1.8
      AAA_21  236 elSdGtkrllalltallralkkgsllliDEpEngLHP....kllrrllellkels 286 
                  ++S G+++ lal+ +l r +   ++++ DE  ++ +     k++r+l+e++k+++
  EEA21213.1 1269 NFSHGQRQQLALARILVRGR---KIVVCDEATSSVDLetddKIQRTLVEFFKNKT 1320
                  56888999988888888877...899999999999999999**********9875 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.8   0.3    0.0012       0.8      26      43 ..     550     567 ..     539     575 .. 0.89
   2 !   20.2   0.3   7.6e-07   0.00053      24      58 ..    1166    1198 ..    1159    1200 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.0012
       DUF87  26 lAilgsTGsGKSntvavL 43 
                 lA++g+TGsGKS + + +
  EEA21213.1 550 LAVIGKTGSGKSSLLSAM 567
                 79**********998766 PP

  == domain 2  score: 20.2 bits;  conditional E-value: 7.6e-07
       DUF87   24 rHlAilgsTGsGKSntvavLleellekkgatilil 58  
                  +H+Ai+g+TG+GKS +v++L++      ++  +++
  EEA21213.1 1166 EHVAIVGRTGAGKSSLVSSLFRVCK--LSGGCILI 1198
                  7******************987544..44555554 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   0.0    0.0015         1      24      50 ..     547     573 ..     539     716 .. 0.78
   2 !   16.2   0.1   1.5e-05     0.011      24     141 ..    1165    1293 ..    1158    1317 .. 0.64

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0015
      AAA_16  24 pelvllsGesGvGKsslvrellralek 50 
                 +el+ ++G  G+GKssl+ +    + k
  EEA21213.1 547 GELLAVIGKTGSGKSSLLSAMTGDIPK 573
                 3899**************987766655 PP

  == domain 2  score: 16.2 bits;  conditional E-value: 1.5e-05
      AAA_16   24 pelvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipy.......sa.laqalareellrqllde.aesaeleawrekleeala..... 106 
                  +e v ++G  G GKsslv +l+r ++k  g ++  + ++  s+ip+       s+ l + + +++ +r  ld+ ++ ++ e wr+   + l+     
  EEA21213.1 1165 GEHVAIVGRTGAGKSSLVSSLFR-VCKLSGGCILIDGVDI-SKIPLedlrsrlSIqLQDSILFRGTIRFNLDPmSQYTDEELWRALHGAHLGnsvhl 1259
                  4899******************5.6666588888888887.66777555555533355555555666555555677777788887666666666654 PP

      AAA_16  107 ..avpelagaea......srllellkrllallsrderplvlvl 141 
                    +v+e            +r   +l+r+l++ ++     ++v+
  EEA21213.1 1260 ddIVQEE----GsnfshgQRQQLALARILVRGRK-----IVVC 1293
                  4322222....13333555555555555544433.....5555 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.7   0.6   5.6e-05     0.038      19      43 ..     544     568 ..     538     569 .. 0.80
   2 !   10.3   0.0   0.00065      0.45      20      40 ..    1163    1183 ..    1157    1189 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 5.6e-05
      AAA_29  19 idlkg.atlltGpsGsGKSTllDAiq 43 
                 ++ kg    ++G++GsGKS+ll A++
  EEA21213.1 544 VQ-KGeLLAVIGKTGSGKSSLLSAMT 568
                 45.3448899************9986 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00065
      AAA_29   20 dlkgatlltGpsGsGKSTllD 40  
                  +  + + ++G++G+GKS+l+ 
  EEA21213.1 1163 EAGEHVAIVGRTGAGKSSLVS 1183
                  4344899************95 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.2   0.1    0.0022       1.5      25      44 ..     548     567 ..     538     570 .. 0.86
   2 ?   -2.9   0.0       5.5   3.8e+03     137     172 ..     644     675 ..     640     713 .. 0.65
   3 !    6.9   0.1    0.0053       3.7      26      46 ..    1167    1186 ..    1160    1193 .. 0.86
   4 !    7.1   0.0    0.0046       3.2     135     209 ..    1248    1338 ..    1188    1344 .. 0.73

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0022
                 SEEEEEESTTSSHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxx RF
       SMC_N  25 sftaivGpNGSGKsnlldAi 44 
                 ++ a++G+ GSGKs+ll A+
  EEA21213.1 548 ELLAVIGKTGSGKSSLLSAM 567
                 4679*************998 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 5.5
                 S-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS- CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 137 LSgGektLvalaLlfAiqkvkpaplyllDeidaaLD 172
                 LSgG+k+ + la       ++ + + llD+  +a D
  EEA21213.1 644 LSGGQKQRIGLAR----AIYSNQKILLLDDPLSAVD 675
                 9999999777653....3344555666666666666 PP

  == domain 3  score: 6.9 bits;  conditional E-value: 0.0053
                  EEEEEESTTSSHHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxx RF
       SMC_N   26 ftaivGpNGSGKsnlldAilF 46  
                  + aivG+ G+GKs+l+ ++ F
  EEA21213.1 1167 HVAIVGRTGAGKSSLVSSL-F 1186
                  689*************998.5 PP

  == domain 4  score: 7.1 bits;  conditional E-value: 0.0046
                  T....................CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC-SCEE CS
                  x....................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  135 e....................lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQfivislreemlekadklv 209 
                                       ++S G+++ +ala ++    v+ + +++ De  +  D +   k+ + l e  kn  ++ i++r +++ + dk++
  EEA21213.1 1248 LhgahlgnsvhlddivqeegsNFSHGQRQQLALARIL----VRGRKIVVCDEATSSVDLETDDKIQRTLVEFFKNKTVLTIAHRIRTIIHYDKVC 1338
                  0555555555555555556668999999999998884....78899**************************************99998887765 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   0.3    0.0011      0.76      98     122 ..     546     570 ..     537     585 .. 0.84
   2 !   10.0   0.1   0.00084      0.58      99     120 ..    1165    1186 ..    1159    1196 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0011
                  TTSEEEEECSTTSSHHHHHHHHCTT CS
  RsgA_GTPase  98 kdktsvlvGqSGvGKStLinallpe 122
                  k+++ +++G++G GKS+L+ a++++
   EEA21213.1 546 KGELLAVIGKTGSGKSSLLSAMTGD 570
                  568999**************99886 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00084
                   TSEEEEECSTTSSHHHHHHHHC CS
  RsgA_GTPase   99 dktsvlvGqSGvGKStLinall 120 
                   ++ +++vG +G+GKS+L+ +l 
   EEA21213.1 1165 GEHVAIVGRTGAGKSSLVSSLF 1186
                   47789*************9986 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.3   0.0    0.0088       6.1      28      59 ..     542     573 ..     537     595 .. 0.80
   2 !   10.5   0.0   0.00046      0.32      27      55 ..    1159    1187 ..    1154    1193 .. 0.88

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0088
       AAA_7  28 lllknkkpvllvGptGtGKtviikdllkkldk 59 
                   ++++  + ++G+tG+GK+++++ ++  ++k
  EEA21213.1 542 VTVQKGELLAVIGKTGSGKSSLLSAMTGDIPK 573
                 56788888999************999988883 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00046
       AAA_7   27 elllknkkpvllvGptGtGKtviikdllk 55  
                  +l ++++ +v +vG tG GK++++++l++
  EEA21213.1 1159 NLAIEAGEHVAIVGRTGAGKSSLVSSLFR 1187
                  678999******************99876 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   0.1    0.0025       1.7      21      40 ..     549     568 ..     537     569 .. 0.87
   2 !    8.1   0.0    0.0051       3.5      22      38 ..    1168    1184 ..    1158    1189 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0025
      AAA_23  21 ltlItGpNGaGKTTildAik 40 
                 l +++G++G+GK+++l A++
  EEA21213.1 549 LLAVIGKTGSGKSSLLSAMT 568
                 56789***********9986 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0051
      AAA_23   22 tlItGpNGaGKTTildA 38  
                  ++I+G +GaGK++++  
  EEA21213.1 1168 VAIVGRTGAGKSSLVSS 1184
                  58***********9865 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.5   0.4     0.007       4.8      42      59 ..     550     567 ..     537     569 .. 0.86
   2 !    9.7   0.0   0.00072      0.49      40      59 ..    1166    1185 ..    1149    1187 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.007
                   EEEE--TTSSHHHHHHHH CS
  FtsK_SpoIIIE  42 llvaGatgsGKStalntL 59 
                   l v+G tgsGKS  l ++
    EEA21213.1 550 LAVIGKTGSGKSSLLSAM 567
                   689************998 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.00072
                    .SEEEE--TTSSHHHHHHHH CS
  FtsK_SpoIIIE   40 shllvaGatgsGKStalntL 59  
                     h+ ++G+tg GKS  + +L
    EEA21213.1 1166 EHVAIVGRTGAGKSSLVSSL 1185
                    6**************99887 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.2     0.087        60      58      75 ..     552     569 ..     541     578 .. 0.84
   2 !   10.1   0.0   0.00046      0.32      52      96 ..    1164    1212 ..    1158    1251 .. 0.73

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.087
      DUF815  58 LwGarGtGKSslvkalln 75 
                 ++G+ G+GKSsl+ a++ 
  EEA21213.1 552 VIGKTGSGKSSLLSAMTG 569
                 68***********99976 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00046
      DUF815   52 pannvLLwGarGtGKSslvkallneyaeeg....Lrlievekedlkelp 96  
                  + ++v ++G  G+GKSslv +l++ ++ +g    +  ++++k  l++l 
  EEA21213.1 1164 AGEHVAIVGRTGAGKSSLVSSLFRVCKLSGgcilIDGVDISKIPLEDLR 1212
                  568999****************998888776544444555555555543 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.0    0.0034       2.3       2      44 ..     549     590 ..     548     622 .. 0.74
   2 ?    4.8   0.0     0.034        23       3      21 ..    1168    1186 ..    1166    1193 .. 0.88

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0034
                 CEEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTT CS
       NACHT   2 lvilqGeaGsGKTtLlqklalawaegklpqgafklvFflslre 44 
                 l+++ G+ GsGK+ Ll  +  ++ + +   + f+  + ++ ++
  EEA21213.1 549 LLAVIGKTGSGKSSLLSAMTGDIPKVHGSLQ-FSSKLAFCPQT 590
                 6899************999888877776654.66666665555 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.034
                  EEEEC-TTTCHHHHHHHHH CS
       NACHT    3 vilqGeaGsGKTtLlqkla 21  
                  v++ G+ G GK+ L+ +l 
  EEA21213.1 1168 VAIVGRTGAGKSSLVSSLF 1186
                  89*************9986 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0     0.028        20      22      49 ..     549     576 ..     543     603 .. 0.84
   2 ?    7.0   0.2    0.0041       2.8      22     147 ..    1167    1296 ..    1160    1313 .. 0.50

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.028
                 EEEEEESTTSSHHHHHHHHCCSHCCCCC CS
      NB-ARC  22 vvalvGmgGvGKttlakqilnksdeveg 49 
                 ++a+ G+ G+GK+ l++ +  +  +v+g
  EEA21213.1 549 LLAVIGKTGSGKSSLLSAMTGDIPKVHG 576
                 689**************99999888887 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0041
                  EEEEEESTTSSHHHHHHHHCCSHCCCCCCBTEEEEEEEES...XXHHH....HHHHXXHHHHHCCCTTSSSS-STTS.....HHHHHHHHCCCT..T CS
      NB-ARC   22 vvalvGmgGvGKttlakqilnksdevegrFdsvawvvvsk...tdkse....eiletilkeLslseddleekeeves.....lkrklvrlLltk..r 104 
                   va+vG+ G GK+ l+++ ++  +   g+   +  v +sk   +d  +    +++++il +   +  +l       +       ++l r+L +    
  EEA21213.1 1167 HVAIVGRTGAGKSSLVSSLFRVCKLSGGC-ILIDGVDISKiplEDLRSrlsiQLQDSILFRGTIR-FNL-------DpmsqyTDEELWRALHGAhlG 1254
                  589****************9985544443.33333333331111111100001222222111111.111.......012222455555555554343 PP

                  EEEEEEEE-SHHHH.....HHHHCHTTSEEEEEESBCCCCCCS CS
      NB-ARC  105 fllvlDDVweeedwdkigvvlparenrlrvllTTRdeevanav 147 
                    + lDD+++ee   + +    ++    r+l+  R+  v++++
  EEA21213.1 1255 NSVHLDDIVQEEGS-NFSHGQRQQLALARILVRGRKIVVCDEA 1296
                  33455666665543.4455555555555555555555555555 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.0       2.5   1.7e+03      18      90 ..     185     280 ..     181     312 .. 0.49
   2 ?    9.8   0.2    0.0011      0.76       1      21 [.     550     570 ..     550     576 .. 0.92
   3 ?    6.5   0.3     0.011       7.9       1      19 [.    1168    1186 ..    1168    1191 .. 0.91

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 2.5
                 HHTS--S---SSS---S-EEEEE.................CCT---CCS...SSEEEET-EB--CHHHHHHHHHHHHHHHTSSSS--SS......- CS
   Dynamin_N  18 LlgedilprgpnptTrrplelql.................geeeeaseravkeelkekekkledfsevreeieketekiagankgiskk......v 90 
                 Ll+ ++l +g+ +  ++  +l+                  + +  a+e+a+  ++ ++ ++   +++ +++++ +++k++++ ++ +++      v
  EEA21213.1 185 LLQNHFLYSGQMVGGQARAILTAkileksmkisesgraggSASAAANEQANMPKNSSQGDEKALINDAKDNQSTKNDKSSSESDSETEQgwsngrV 280
                 555555555555444444444443343343444444333211111112233333333355555566666666666666554444443335555552 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.0011
                 EEEEEBTTTTHHHHHHHHHTS CS
   Dynamin_N   1 iavvGsqSsGKSSvlnaLlge 21 
                 +av+G++ sGKSS+l a++g+
  EEA21213.1 550 LAVIGKTGSGKSSLLSAMTGD 570
                 69***************9985 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.011
                  EEEEEBTTTTHHHHHHHHH CS
   Dynamin_N    1 iavvGsqSsGKSSvlnaLl 19  
                  +a+vG + +GKSS++ +L 
  EEA21213.1 1168 VAIVGRTGAGKSSLVSSLF 1186
                  79************99986 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.1    0.0057       3.9       5      25 ..     547     567 ..     544     587 .. 0.87
   2 ?    7.1   0.1    0.0091       6.3       6      26 ..    1166    1186 ..    1162    1191 .. 0.87
   3 ?   -0.9   0.1       2.6   1.8e+03      82     117 ..    1280    1317 ..    1240    1332 .. 0.64

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0057
      AAA_22   5 agilvvtGesGtGKTtllrrl 25 
                   +l+v+G +G+GK+ ll  +
  EEA21213.1 547 GELLAVIGKTGSGKSSLLSAM 567
                 5689************99876 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0091
      AAA_22    6 gilvvtGesGtGKTtllrrll 26  
                   +++++G +G+GK+ l+  l+
  EEA21213.1 1166 EHVAIVGRTGAGKSSLVSSLF 1186
                  6899***********998876 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 2.6
      AAA_22   82 leqalraravielliiDEaqh.lr...seealeeLrslln 117 
                  l++ l +   +++++ DEa   ++    +++ ++L+++++
  EEA21213.1 1280 LARILVRG--RKIVVCDEATSsVDletDDKIQRTLVEFFK 1317
                  33334444..469******987744322444444444433 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.1     0.013         9      31      54 ..     545     568 ..     536     581 .. 0.89
   2 ?    6.2   0.1    0.0097       6.7      30      54 ..    1162    1186 ..    1154    1196 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.013
      AAA_25  31 pagelallaGapgtGKttlaldla 54 
                  +gel +++G +g+GK+ l++ + 
  EEA21213.1 545 QKGELLAVIGKTGSGKSSLLSAMT 568
                 689****************99876 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.0097
      AAA_25   30 lpagelallaGapgtGKttlaldla 54  
                  + age ++++G++g+GK+ l+++l 
  EEA21213.1 1162 IEAGEHVAIVGRTGAGKSSLVSSLF 1186
                  679999***************9985 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.0     0.024        17      44      68 ..     544     568 ..     539     583 .. 0.87
   2 ?    5.8   0.0     0.015        10      44      67 ..    1162    1185 ..    1153    1218 .. 0.91

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.024
   IstB_IS21  44 iekkenivllGpsGvGKshlaialg 68 
                 ++k e ++++G +G GKs l  a+ 
  EEA21213.1 544 VQKGELLAVIGKTGSGKSSLLSAMT 568
                 6788999*************99986 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.015
   IstB_IS21   44 iekkenivllGpsGvGKshlaial 67  
                  ie+ e ++++G +G+GKs l  +l
  EEA21213.1 1162 IEAGEHVAIVGRTGAGKSSLVSSL 1185
                  78899*************998776 PP

>> AF-4  AF-4 proto-oncoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   3.6   0.00013     0.087     421     493 ..     207     276 ..     182     282 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00013
        AF-4 421 ksmLeddLklsssedsdeeqapekpksssapssapqstpesvesahsssaeSeSsSeSeSSSeSDSesEssss 493
                   +Le  +k+s+s     +  +  +++ + p++++q  ++   +  +  ++ +S+ +  SSSeSDSe+E   s
  EEA21213.1 207 AKILEKSMKISESGRAGGSASAAANEQANMPKNSSQGDEK---ALINDAKDNQSTKNDKSSSESDSETEQGWS 276
                 4789************999999999999999987766665...77788888899999************8655 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0       6.5   4.5e+03      86     106 ..     257     277 ..     248     301 .. 0.79
   2 ?    3.4   0.1     0.079        54       5      22 ..     550     567 ..     546     575 .. 0.85
   3 ?    6.4   0.0    0.0096       6.6       4      47 ..    1167    1207 ..    1164    1311 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 6.5
      AAA_24  86 irqnekaeskedkgdgkGyge 106
                  ++n k +s++d  + +G+++
  EEA21213.1 257 STKNDKSSSESDSETEQGWSN 277
                 5667777888999999**986 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.079
      AAA_24   5 iliyGpsgiGKTtlakel 22 
                 ++++G+ g+GK++l++ +
  EEA21213.1 550 LAVIGKTGSGKSSLLSAM 567
                 689***********9988 PP

  == domain 3  score: 6.4 bits;  conditional E-value: 0.0096
      AAA_24    4 kiliyGpsgiGKTtlakelgpkplfidtekGlksldadkfpdie 47  
                   ++i+G  g+GK++l+++l   + ++ + +G   +d+ ++ +i+
  EEA21213.1 1167 HVAIVGRTGAGKSSLVSSL---FRVCKLSGGCILIDGVDISKIP 1207
                  589****************...9999999999999999988885 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.0     0.045        31       3      21 ..     551     569 ..     550     600 .. 0.85
   2 ?    5.7   0.1     0.024        17       2      20 ..    1168    1186 ..    1167    1207 .. 0.90

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.045
                 EEESSTTSSHHHHHHCHCT CS
         Roc   3 vlvGdsgvGKtsllkrfve 21 
                  ++G++g+GK+sll+ ++ 
  EEA21213.1 551 AVIGKTGSGKSSLLSAMTG 569
                 68************98875 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.024
                  EEEESSTTSSHHHHHHCHC CS
         Roc    2 vvlvGdsgvGKtsllkrfv 20  
                  v +vG +g+GK+sl++++ 
  EEA21213.1 1168 VAIVGRTGAGKSSLVSSLF 1186
                  789************9875 PP

>> AAA_10  AAA-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.2      0.35   2.4e+02      24      39 ..     550     565 ..     541     571 .. 0.81
   2 ?    9.6   0.1   0.00057      0.39      22      54 ..    1166    1198 ..    1160    1206 .. 0.89

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.35
      AAA_10  24 sliiGdlGnGKSvlak 39 
                  ++iG++G GKS l  
  EEA21213.1 550 LAVIGKTGSGKSSLLS 565
                 489*********8765 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00057
      AAA_10   22 sasliiGdlGnGKSvlakllvlyisllggkali 54  
                   +++i+G +G+GKS l+  l+  + l gg +li
  EEA21213.1 1166 EHVAIVGRTGAGKSSLVSSLFRVCKLSGGCILI 1198
                  588***********************9998876 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.1     0.061        42      18      41 ..     549     572 ..     539     582 .. 0.79
   2 ?    6.5   0.1    0.0065       4.5      19      51 ..    1168    1200 ..    1163    1206 .. 0.89

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.061
  Zeta_toxin  18 lillgGqpGAGKselaellkdele 41 
                 l+ + G +G+GKs+l+++++ ++ 
  EEA21213.1 549 LLAVIGKTGSGKSSLLSAMTGDIP 572
                 556779***********9987765 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0065
  Zeta_toxin   19 illgGqpGAGKselaellkdelerqgnvvrldp 51  
                  + ++G +GAGKs+l + l +  +  g+++ +d+
  EEA21213.1 1168 VAIVGRTGAGKSSLVSSLFRVCKLSGGCILIDG 1200
                  6689**************999999999999997 PP

>> ATP_bind_1  Conserved hypothetical ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.3     0.053        37       1      17 [.     552     568 ..     552     578 .. 0.88
   2 ?    6.5   0.2    0.0091       6.3       1      24 [.    1170    1193 ..    1170    1198 .. 0.91

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.053
  ATP_bind_1   1 vvGpaGsGKttfvgals 17 
                 v+G  GsGK+++ +a++
  EEA21213.1 552 VIGKTGSGKSSLLSAMT 568
                 89***********9997 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0091
  ATP_bind_1    1 vvGpaGsGKttfvgalseilelrg 24  
                  +vG  G+GK+++v++l  +++l+g
  EEA21213.1 1170 IVGRTGAGKSSLVSSLFRVCKLSG 1193
                  79*****************99875 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.2    0.0057         4      23      43 ..     546     567 ..     538     569 .. 0.81
   2 ?    1.8   0.0      0.22   1.5e+02      20      44 ..    1163    1186 ..    1159    1332 .. 0.81

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0057
      AAA_15  23 ee.ltvliGkNnsGKSsileal 43 
                 +  l  +iGk +sGKSs+l a+
  EEA21213.1 546 KGeLLAVIGKTGSGKSSLLSAM 567
                 444999*************997 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.22
      AAA_15   20 dlseeltvliGkNnsGKSsileald 44  
                  +  e    ++G+ ++GKSs++  l 
  EEA21213.1 1163 EAGE-HVAIVGRTGAGKSSLVSSLF 1186
                  5556.678************99884 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1395 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       883  (0.0492498); expected 358.6 (0.02)
Passed bias filter:                      533  (0.0297284); expected 358.6 (0.02)
Passed Vit filter:                        82  (0.0045736); expected 17.9 (0.001)
Passed Fwd filter:                        26  (0.00145016); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              26  [number of targets reported over threshold]
# CPU time: 1.06u 0.37s 00:00:01.43 Elapsed: 00:00:00.51
# Mc/sec: 8248.25
//
Query:       EEA21214.1  [L=193]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (193 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       336  (0.0187406); expected 358.6 (0.02)
Passed bias filter:                      317  (0.0176809); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.39u 0.25s 00:00:00.64 Elapsed: 00:00:00.39
# Mc/sec: 1466.62
//
Query:       EEA21215.1  [L=498]
Description: N-alkane-inducible cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.3e-52  179.1   0.0    1.8e-52  178.6   0.0    1.1  1  p450        Cytochrome P450
  ------ inclusion threshold ------
      0.077   13.1   0.0       0.14   12.2   0.0    1.4  1  Toxin_YhaV  Toxin with endonuclease activity, of toxin-antito


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  178.6   0.0     2e-56   1.8e-52      28     445 ..      78     477 ..      54     493 .. 0.83

  Alignments for each domain:
  == domain 1  score: 178.6 bits;  conditional E-value: 2e-56
                 HHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHHHHHHHHHTSHSTTTHHHHHHHHHHHHH CS
        p450  28 klqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkklRrfltptltsfgklsleelveeeaedlv 126
                 k + + g + +  + ++++v+ ++pe  k vl ++   f +++  + ++ + +p +g+g+++++ + w+  R+++ p +t   + +  e +e  ++ l+
  EEA21215.1  78 KKALEIGRTHTAVILGQNIVFTCDPENLKTVLATN---FLDYGLGPRVH-FMGPLLGEGIFTSDDAAWHHSRDLIRPCFTRT-QIADLEALENHVQALI 171
                 444456888899999********************...55555555555.456***************************99.3345566677777777 PP

                 HHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHH..HHHCHHHHCCCCCHHHTCCSCHHHHHHHHHHHHHHHHHHHH CS
        p450 127 eklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelss..llskssvqllllfpllkylptkllrklkeavkklkdlldkl 223
                   l ++ ++   +d+++l+ ++++d+ ++ l+g ++++ ++   s  +++ ++l        ++  l ++ +ll         k++e +k+++ +++++
  EEA21215.1 172 SCLPPNGTT---VDLQPLFYNFTIDSATEFLVGQSVGCQGSGPGSAGLEFSQALDYaeAAIEKRNALGKHAWLL------RDPKFHESCKVVHRFTENF 261
                 777665555...5************************9998886655555555522112224444555555533......355888899********** PP

                 HHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHCCTTTT-HHHHCCT-H CS
        p450 224 ieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklreEidevlgdkreptyddlqklp 322
                 i+e  +   +    r+++l+ l ++          +   l++++l++l+a+ dTt+s l  ++y+La+nP++ +klr E+ e  g+   p+y+ l++++
  EEA21215.1 262 INETLKGNAKP--GRYNLLAELANSC--------RDPIRLRNELLNVLVAARDTTASLLGSMFYFLAHNPDTWDKLRTEVGELNGR--IPDYQTLKDMK 348
                 *****999999..8999999999996........35689********************************************999..7********** PP

                 HHHHHHHHHHHHSCSSTTEEEEESSSCEEETT.........EEE-TT-EEEEEHHHHHT-TTTS.SSTTS--GGGGB-TTSCTESSCTT--TTEEGGGS CS
        p450 323 yldavikEtLRlhpvvplllpRevtkdvvirg.........ylipkGtevivnlyalhrdpevf.pnPeeFdpeRFldekgnskrksfaflPFGaGpRn 411
                 yl+ v++EtLRl+p+vp l +R + kd+v+++          ++ kG++v+ ++ya+hr pe++ ++P+ ++peR+ d k    r+   fl+F  GpR 
  EEA21215.1 349 YLKSVLNETLRLIPPVP-LNERFARKDTVLPHgggadgqspIFVAKGSRVVSSVYAMHRLPEIWgNDPQLYRPERWFDGKL---RPGWGFLAFNGGPRT 443
                 *****************.999*********977888899999*************************************87...9************** PP

                 -TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGE CS
        p450 412 CiGerlArmelklflatlLqnFevelqpetdppp 445
                 C+G++ A +e ++ +++lLq F+   +++++p+ 
  EEA21215.1 444 CLGQQKALVETSYTVVRLLQVFDRIEPRDDQPWL 477
                 **********************988655555544 PP

>> Toxin_YhaV  Toxin with endonuclease activity, of toxin-antitoxin system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   1.6e-05      0.14       9      64 ..     322     376 ..     315     381 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 1.6e-05
  Toxin_YhaV   9 eqleelvekveklkakdpedykkkaavkllaaiaklilekipadPtaseyrlgktL 64 
                 +++++l+++v +l+ + p dy++ +++k l+++ +  l+ ip  P +++++ ++t+
  EEA21215.1 322 DTWDKLRTEVGELNGRIP-DYQTLKDMKYLKSVLNETLRLIPPVPLNERFARKDTV 376
                 57999********99998.8********************************9997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (498 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       389  (0.0216967); expected 358.6 (0.02)
Passed bias filter:                      383  (0.021362); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 3411.23
//
Query:       EEA21216.1  [L=360]
Description: alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-09   38.2   0.0    2.4e-09   37.2   0.0    1.5  1  ADH_zinc_N    Zinc-binding dehydrogenase
    1.6e-06   27.9   1.0    3.6e-06   26.8   0.8    1.6  2  ADH_N         Alcohol dehydrogenase GroES-like domain
     0.0053   17.8   0.0      0.011   16.8   0.0    1.5  1  ADH_zinc_N_2  Zinc-binding dehydrogenase
  ------ inclusion threshold ------
       0.16   12.1   0.0       0.27   11.3   0.0    1.3  1  Cpn10         Chaperonin 10 Kd subunit


Domain annotation for each model (and alignments):
>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.2   0.0   5.5e-13   2.4e-09       3      83 ..     177     255 ..     175     275 .. 0.92

  Alignments for each domain:
  == domain 1  score: 37.2 bits;  conditional E-value: 5.5e-13
                 HHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTESEEEETTTC.HHHHHHHHHTTTSSEEEEEESSCSHHHHHHHHHCEEEEE CS
  ADH_zinc_N   3 GlaavqlAkalGaeviavdsseeklelakklGadevinykea.dlverikeltggegvdvvfecvGsgatleaalkllkpgG 83 
                 G++ +ql++++G+ +i+++s ++++el+k++Gad v++y +a d  + i++   g+ + +v++cv   ++++ +++++ + G
  EEA21216.1 177 GTMMLQLLHICGFSTITTCS-PHNFELVKSYGADKVYDY-KApDCPQNIRSDS-GNLLEYVIDCVSEDSSMKFCYAAIGRAG 255
                 99***********9999986.557***************.777**********.99*****************999998887 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.8   8.1e-10   3.6e-06       1      62 [.      35      93 ..      35     101 .. 0.93
   2 ?   -2.1   0.0      0.77   3.4e+03      90     100 ..      98     112 ..      91     119 .. 0.73

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 8.1e-10
                TTEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS.--TT-EEEE- CS
       ADH_N  1 pgevlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkk.lkvGdrVvve 62
                p+e+lik++a++++  D +++ g     v +++++G + +G+v+++g++v+k lkvGdrV+ +
  EEA21216.1 35 PDEILIKTSAVALNPVDTKLVGG----FVTPGCVFGFDCAGVVVAIGSDVHKdLKVGDRVCGS 93
                689******************99....89*********************999*******975 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.77
                 S....S-SSSBSEEE CS
       ADH_N  90 s....ldGgfaeyvv 100
                 +    l G+faeyv 
  EEA21216.1  98 NkekpLGGAFAEYVK 112
                 34456789*****86 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.0   2.4e-06     0.011       2     105 ..     207     326 ..     206     330 .. 0.72

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 2.4e-06
                   T-SEEEETTSTTHH...HHH-TT-EEEEEES-HHHHH.HHHHHHE.EEEEEEEE----..........S-EEE-CHHHCTTT-EEEE--GGG...-. CS
  ADH_zinc_N_2   2 GAdevidyrtedfe...aatggegvDvvldtvggealleaslkvl.pggGrlvsiggpp.........lsaallkpakkrkgrsvkyeflfsmkas. 84 
                   GAd+v+dy+++d     ++ +g+   +v+d+v  ++ ++ + +++ +  G + + ++p          +              + ++++ + + a+ 
    EEA21216.1 207 GADKVYDYKAPDCPqniRSDSGNLLEYVIDCVSEDSSMKFCYAAIgRA-GGYYTALNPYndrlatrkvI--------------TPDWVLAT-RIAGd 287
                   9**********9999998888999*********999989999999777.88888887645555554442..............44444444.23333 PP

                   ....................-HHHHHHHHHHHHHHH---- CS
  ADH_zinc_N_2  85 ...................aqadileelaalieeGklrpv 105
                                      a+   +e++ +l+ eGk++p+
    EEA21216.1 288 gsswpapyacdpeprlrdlAGPL-FERIQKLLNEGKIKPH 326
                   44444444555558777744555.8999999999999998 PP

>> Cpn10  Chaperonin 10 Kd subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0     6e-05      0.27       7      68 ..      36      94 ..      34     112 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 6e-05
                TEEEEEE....SGG.-TTS-TT----HHHHHSEEEEEEEEE-T........TS-TTS--T-EEEEEG CS
       Cpn10  7 drVlvkr....aee.eekteggiilpdsakekpeqGvVvaVGegarnekgedvplevkvgdkVlfpk 68
                d +l+k+     +  ++k  gg + p       + GvVva+G+        dv  ++kvgd+V  + 
  EEA21216.1 36 DEILIKTsavaLNPvDTKLVGGFVTPGCVFGFDCAGVVVAIGS--------DVHKDLKVGDRVCGSA 94
                56666665543233477788888888888888899********........8999********8554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (360 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       324  (0.0180713); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2551.00
//
Query:       EEA21217.1  [L=565]
Description: cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      7e-71  239.3   0.0      9e-71  239.0   0.0    1.0  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  239.0   0.0     5e-75     9e-71       1     445 [.      72     527 ..      72     544 .. 0.88

  Alignments for each domain:
  == domain 1  score: 239.0 bits;  conditional E-value: 5e-75
                 --SESEHHCCHCHHHHTT..TCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHH CS
        p450   1 Ppgptplplvgnllqlgr..keelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkk 97 
                 P++    +l+g++ ql r  + e  + lr++++  g i+   l + + vv+++p +v e+  + + ef++    + +a    + +g+g+++++ ek+k+
  EEA21217.1  72 PQPKGGSWLIGHWWQLFRngTAESERWLREIEND-GFIYYRSLLNSQRVVITTPALVGEICTRVD-EFVKPVIARGIAG---RILGEGLVLSELEKHKQ 165
                 5666688999999999875555566666666666.8899999999999999************97.6666556666665...89*************** PP

                 HHHHHHHHHTSHSTTTHHHHHHHHHHHHHHHHHCCCCHCS....EEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHH....HHHCHH CS
        p450  98 lRrfltptltsfgklsleelveeeaedlveklrkkagess....elditellskaaldvigsilFgarfdlledeklselvkaveelss....llskss 188
                 +Rr+++p +    ++++ +++   ++dl +k+  +a +      ++++ ++ s+ ald++++ + g+ f++++de+++ ++++ +++      +    +
  EEA21217.1 166 QRRIFLPIFAPRHIREMFPIFWGKTRDLTQKMTHEALSEPhrdaVFEVGRWASRGALDIVTMATIGEDFGSIQDENATLAKTFRRAIEPsrgyI-VLAM 263
                 **********99888*****************999988877999*******************************9544444444443244543.3578 PP

                 HHCCCCCHHHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        p450 189 vqllllfpllkylptkllrklkeavkklkdlldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLy 287
                  +++l+ +l+++lp+k++r++ e v +l dl ++l+++rr++  +++++ +d+l+++   +   +  +  ++ee+  +++++l+aG++T s +++wa y
  EEA21217.1 264 LEIWLPAWLVHILPNKMNRTMGESVPILRDLCRHLLRKRRQQSLEKSSDGKDLLSLCFHYE---EV-ARANEEEVIDQMTTFLAAGHETISVGITWAVY 358
                 8***************************************999999889999999998885...33.4789**************************** PP

                 HHHHSHHHHHHHHHHHHHHCCTTT.......T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEETTEEE-TT-EEEEEHHHHHT-TTTS.S CS
        p450 288 eLaknPevqeklreEidevlgdkr.......eptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirgylipkGtevivnlyalhrdpevf.p 378
                  L  +Pe q  lreE +  l+d           t +d+ ++p+ +a+i+E+LR +p++p +++Re+++d+vi+g++ipkGt + +++ + hrd+ v+ p
  EEA21217.1 359 MLCLYPEWQTLLREEARANLPDPNanidqsrMATSADVDNMPLIQAFINEVLRWYPPIP-QTMRETLQDTVIGGRVIPKGTWIALPIKGFHRDERVWgP 456
                 *****************99966555788888999*************************.*************************************** PP

                 STTS--GGGGB-TTS......CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGE CS
        p450 379 nPeeFdpeRFldekg......nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdppp 445
                 ++++F+p R+l+++g         ++++  l+F  G R+C+ +++ + e+  +++ l+ +F++el + +d  +
  EEA21217.1 457 DANQFNPRRWLNADGsvningG-CQNKYFNLAFMQGSRSCVAQGFSKAEMACVIGALVGHFSFELVD-SDLLD 527
                 *****************99753.3788999**********************************954.44444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (565 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       345  (0.0192426); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.43
# Mc/sec: 3974.79
//
Query:       EEA21218.1  [L=276]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.5e-24   85.0   0.0    8.2e-23   81.2   0.0    2.0  1  FSH1      Serine hydrolase (FSH1)


Domain annotation for each model (and alignments):
>> FSH1  Serine hydrolase (FSH1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.2   0.0   4.6e-27   8.2e-23       6     207 ..       2     258 ..       1     263 [. 0.85

  Alignments for each domain:
  == domain 1  score: 81.2 bits;  conditional E-value: 4.6e-27
        FSH1   6 kiLcLhGytqsgeiFraktsalrkllkklnvelvyldaplelaekadlpkseseeeekseeeeesraWfrkkdekneyegleesldavkdyikengpfd 104
                 + L+LhG+++s+ iF+a+t  ++  l k +++++++d+p+++a++a l ++           +++++W++ +d    ++++++s + +++yi++ngp+d
  EEA21218.1   2 RTLMLHGHATSAFIFKAQTLPVQTRLDK-DFSFDFVDGPIRCAPPAGLASV----------VKTAYTWYKAPD----ATSIRNSASWLARYIDKNGPYD 85 
                 78*************************9.*************999988755..........8999*****998....999******************* PP

        FSH1 105 GiiGFSqGaalaallaslleellkea..shpslkfailv.sGfkleepk.................................................. 150
                  i+ FS  a+++ ++++   ++++++  ++   k+++++ +G +   ++                                                  
  EEA21218.1  86 CICCFSKAAVVVLAMLMYEVPQRTDEskERITPKCLVFInAGLEYSFLEelglpiteearrikfrmeqlvrsktnalsnlskatsrpgatnglwddtsk 184
                 *********8765555555444444422666669999985788776666788999999999********999999999999999999999999999999 PP

        FSH1 151 ..................yeeyy.eedkiqtptLhvlGelDtvvdeerseaLaeafkns.skvlkHpggHfvPnkke 207
                                         ee  i++pt+h+lG +D + +     +La+ ++++ + ++ H+ggH +P++ +
  EEA21218.1 185 llhnpnkmpppsscfgldLT-SWpEEFVIKLPTVHILGGKDPLWP--SGVQLANLCDEDtRSFYDHQGGHDLPRTPK 258
                 99888887777777665422.22456678****************..99**********9*************9765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (276 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       307  (0.0171231); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.48
# Mc/sec: 1728.95
//
Query:       EEA21219.1  [L=181]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       361  (0.020135); expected 358.6 (0.02)
Passed bias filter:                      273  (0.0152267); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.46
# Mc/sec: 1186.38
//
Query:       EEA21220.1  [L=2558]
Description: polyketide synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.9e-63  213.8   0.1    5.8e-63  212.8   0.1    1.5  1  ketoacyl-synt    Beta-ketoacyl synthase, N-terminal domain
    7.1e-49  166.2   0.0    3.5e-48  163.9   0.0    2.1  2  KR               KR domain
    3.8e-45  154.4   0.0    6.9e-45  153.6   0.0    1.4  1  PS-DH            Polyketide synthase dehydratase
    1.1e-37  130.2   0.1    2.5e-37  129.1   0.1    1.5  1  Acyl_transf_1    Acyl transferase domain
    2.7e-29  101.6   0.0    7.7e-29  100.1   0.0    1.8  1  Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
      9e-19   68.1   0.0    4.5e-18   65.8   0.0    2.3  2  Methyltransf_12  Methyltransferase domain
    1.6e-15   57.5   0.0    4.3e-15   56.2   0.0    1.7  1  KAsynt_C_assoc   Ketoacyl-synthetase C-terminal extension
    2.7e-15   56.6   0.0    5.6e-14   52.3   0.0    2.4  2  Methyltransf_23  Methyltransferase domain
      1e-12   48.5   0.1      2e-11   44.4   0.0    3.4  2  Methyltransf_25  Methyltransferase domain
    1.4e-11   44.9   0.0    5.1e-11   43.1   0.0    2.1  1  Methyltransf_11  Methyltransferase domain
    5.4e-11   42.5   0.0    1.2e-10   41.4   0.0    1.5  1  Methyltransf_31  Methyltransferase domain
      1e-08   34.9   0.1    5.2e-08   32.6   0.0    2.1  2  adh_short        short chain dehydrogenase
    6.9e-08   32.7   0.1      2e-07   31.2   0.1    1.9  1  PP-binding       Phosphopantetheine attachment site
    7.5e-06   25.7   0.0    3.1e-05   23.6   0.0    2.1  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
      6e-05   22.5   0.0    0.00013   21.4   0.0    1.4  1  Ubie_methyltran  ubiE/COQ5 methyltransferase family
     0.0003   20.2   0.2    0.00057   19.3   0.2    1.3  1  Thiolase_N       Thiolase, N-terminal domain
     0.0012   18.7   0.0     0.0025   17.6   0.0    1.5  1  Methyltransf_16  Lysine methyltransferase
  ------ inclusion threshold ------
       0.11   12.1   0.0       0.22   11.1   0.0    1.4  1  NodS             Nodulation protein S (NodS)
       0.19   10.8   0.0       0.55    9.3   0.0    1.7  2  DREV             DREV methyltransferase


Domain annotation for each model (and alignments):
>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  212.8   0.1   6.1e-66   5.8e-63       2     253 .]       6     249 ..       5     249 .. 0.95

  Alignments for each domain:
  == domain 1  score: 212.8 bits;  conditional E-value: 6.1e-66
                    --EEEEEEEEEBTTBSS.HHHHHHHHHTT---EEES-TTSSCGTTSBTSSTTEEE-BSS.EEE..S..TTEGGTTSTHHHHHHHCTS-HHHHHHHH CS
  ketoacyl-synt   2 epvaivGmgarfPggnd.veefwelLlegrdaiselpadrwdadklydpparaagkiktklggfld..vddfdpeffgispreaeamdpqqrllle 94 
                    ep+a++G g+rfPgg + ++ +w+l+ e rd  s+++  r++ad++y+++   +g++++ + ++l    + fd++ff+i+++ea a+dpqqr+lle
     EEA21220.1   6 EPIAVIGSGCRFPGGATsPSRLWDLMKEPRDVASKIE--RFSADGFYHKDGGHHGTSNVLHSYLLGddTSVFDAQFFNIPASEASAIDPQQRMLLE 99 
                    89*************999*******************..9******************9888888778899************************* PP

                    HHHHHHHHHTS-HHTCTTGGEEEEEEESSTHHHHHHHHHHHTTGGGSCTTHHHHHSTTHHHHHHHHHHT--SSEEEEESGGGHHHHHHHHHHHHHH CS
  ketoacyl-synt  95 aawealedagltpeeldgsrvgvfiGvgagdyaalaaldedgsevkaspkavgavlanviagrisyalglrGpsvtvdtACsSslvavhaavqslr 190
                    +++eale +g + eel+gs ++v++G++++dya++  +d +      +  a+g+ +++++++r+s     +Gps+t+dtACsSsl avh+avq+lr
     EEA21220.1 100 VVYEALEASGHKIEELSGSPTAVYVGLMCNDYAHIIYHDLES--LPKYA-ATGT-ASSILSNRVS-----TGPSMTIDTACSSSLIAVHQAVQALR 186
                    ********************************8877766444..67777.9999.*********8.....7************************* PP

                    TTS-SEEEEEEEE---SHHHHHHHHHTTBB-TTSGGGTTBTTB-SB-BB-EEEEEEEEECHHH CS
  ketoacyl-synt 191 sgeadvalaGGvellltpeavagfsaagllspdgrckafdpkadGfvlGEGvGavvLkrleda 253
                     +++ +a+a G++l+++p ++++ s+ ++lsp+gr++  +++adG+ +GEGv+av+Lkrl+da
     EEA21220.1 187 LKQSNLAVAAGANLIFGPTNYVAESNVNMLSPTGRSRMWSKNADGYARGEGVAAVILKRLSDA 249
                    *************************************************************98 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0       1.9   1.8e+03      86     141 ..    1494    1547 ..    1491    1556 .. 0.88
   2 !  163.9   0.0   3.7e-51   3.5e-48       2     176 ..    2121    2292 ..    2120    2296 .. 0.96

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 1.9
                  EE---------TTT--HHHHHHHHTTTTHHHHHHHHHTTTS--SEEEEEEEHHHHH CS
          KR   86 ihaAgvlrdklleemtaedleqvlapKvkGawnLhelledesldffvlfSSiagll 141 
                  i a  vl+ +++ e+t ++++++l+p   G  +L e++ ++++    +f S+ g +
  EEA21220.1 1494 IVASNVLHATKFLEKTLKNVRKLLRP--GGYLVLLEITDNDPVRQSFFFGSLPGWW 1547
                  56788999*****************9..799*********9999999999988866 PP

  == domain 2  score: 163.9 bits;  conditional E-value: 3.7e-51
                  EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TT CS
          KR    2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklle 98  
                  ty ++G +G LG +l+rw++e+gar +vl+sRs  ++ d +++++ ++alga+v+v+++D++d+++v+++ + ik++ pp++Gv + A+vl+d+l++
  EEA21220.1 2121 TYWLAGLTGDLGISLTRWMVERGARYVVLTSRS--PKVD-QKWLEGMTALGATVTVLPMDITDEKQVSETYHIIKETLPPVAGVCNGAMVLNDGLIA 2214
                  89*******************************..4445.55******************************************************* PP

                  T--HHHHHHHHTTTTHHHHHHHHHTTTS--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHHHHHTEEEEEE- CS
          KR   99 emtaedleqvlapKvkGawnLhelledesldffvlfSSiagllgsagqanYaaaNaflDalaeyrrsqglpavsinwg 176 
                  +++ ed++  l+pKvkG++ L+ l+++ +ldff++fSS+a ++g+ gqa+YaaaN f+ ++ae rr++gl++ ++n+ 
  EEA21220.1 2215 NQSFEDFNGTLEPKVKGTRYLNALFQKPDLDFFIIFSSLAYTTGNIGQASYAAANGFMVSMAEGRRRRGLAGSVMNMA 2292
                  ************************************************************************999975 PP

>> PS-DH  Polyketide synthase dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  153.6   0.0   7.3e-48   6.9e-45       1     293 [.     941    1240 ..     941    1245 .. 0.89

  Alignments for each domain:
  == domain 1  score: 153.6 bits;  conditional E-value: 7.3e-48
                  BTTB.-EE--.-SS-EEEEEEE-S-SS.TTTSEEETTEEB--TTHHHHHHHHHHHHTS---.....-EEEEEEEE----.B--SS.-EEEEEEEEE- CS
       PS-DH    1 hpllGsrvrsasdkevvfrnrlrlaelpwLrDHrvdgkvvlPgagylemaleAarqltges....kavelrdvsilkalvlpede.pvevqlslepe 92  
                  h+llG +++s   +e+++rn l+++e pw+r H+++g++++Pgag+  ma+eA +  + ++    + +el++++i++al + +++ + ev+++l   
  EEA21220.1  941 HELLGIKLDSG-EHELRWRNFLKPNEIPWVRGHSIQGQTIFPGAGFAVMAMEATKAFVADTgeemELIELENLTIHRALGFIDENiGSEVMVTLSNI 1036
                  99********6.*********************************************977778899*************9999999*********** PP

                  TTS-E....EEEEEEE-SS-TT.EEEEEEEEEE-------B--HHHHHHHS-SEE....E-HHHHHHHHHHHSEEE-GGG--EEEEEEETTEEEEEE CS
       PS-DH   93 edgadrawvefeifSregggeewtehatGtvrlaegaaaaavdlealqarcaepaslrsvssaefYerlaargleyGpsFqglralwrgdgealael 189 
                  e++       f++ ++ ++++  t  +t++vrl+ g+   + +l+ + ++++e  ++++v+ + fY +la+ g++y + F+ +++l r   +a +++
  EEA21220.1 1037 ERKFGLVLCNFTCEACPTKDASPTIFSTARVRLRLGPG-SRDTLPPR-EPAPEGHKITEVDTEVFYSSLAKLGYNYADMFKSITNLSRWGLAASGQI 1131
                  88777777899999999998889*********999988.33334443.5566666789******************************777888888 PP

                  ---GGGSSTTTT-SB-HHHHHHHHHHG..GG.----------EEEEEEEEEEE-S.......-BTS--EEEEEE.----SS-EEEEEEEE-SS-BEE CS
       PS-DH  190 rlpeelaggesayvlhPallDaalQllaaal.saeaekadaaylPvaierlrvyr....pssaageelwvharl.eeegarsivadltlvdedGrvv 280 
                  +   e+   e ++++hPa lD+a+Q l+ a+    + +  ++++P+ i  ++v++    ++s  g +l  +a++  +e+ +++++d++++d +G++v
  EEA21220.1 1132 NSVGETG-YETDLIVHPAPLDVAFQGLFCAIgAPGDGQLWTLMVPTVIRNIKVNPvtcnQTSCLGTDLMFDAKVqLGESRQQVSGDIDVYDTEGNAV 1227
                  7776654.6677*************555566656789*********************9999999*******9996677789*************** PP

                  EEEESEEEEE--X CS
       PS-DH  281 aeieglrlrrver 293 
                  ++iegl++++v +
  EEA21220.1 1228 LQIEGLEVTSVVQ 1240
                  *********9865 PP

>> Acyl_transf_1  Acyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  129.1   0.1   2.6e-40   2.5e-37       3     272 ..     544     841 ..     543     876 .. 0.82

  Alignments for each domain:
  == domain 1  score: 129.1 bits;  conditional E-value: 2.6e-40
                    EE--TT---TTTTCCHHHC-HHHHHHHHHHHHHCCH.....HHT--H.HHHHHS--TTGGGSHHHHHHHHHHHHHHHHHHHHHTT-TTSEEEE-TT CS
  Acyl_transf_1   3 vfsGqGsQwaGMGmeLlktskafaaviaradeafks.....qygfsv.ldvlrnnpeglldaiqfvqpaLaavqialaellkskGvrpaavvGHSl 92 
                    +f+GqG+Qw  MG +L+++s+++ + i+ ++ +++s        +s+ +++ ++++ + +++  f+qp  +avq+  ++ll+ +G + ++vvGHS 
     EEA21220.1 544 IFTGQGAQWPQMGHNLIESSPLATKLIDSLNTSLQSlpeqdRPQWSLrAELCKAADSSHVMEGAFSQPLCTAVQVLIVDLLQDAGITFDVVVGHSS 639
                    8*******************************998522211457***4578899999*************************************** PP

                    HHHHHHHHCCSSSHHHHHHHHHHHHHHHHHHTS-EECCEECS.........HHHHHHH.....TT.EEEEEEECCCCECCEEHHHHHHHHHHHHHC CS
  Acyl_transf_1  93 GElAaavvagalsseeallavvlrsrlmmqlagpgdmaavel........aeeeeklr...cqddvvgavansprrvvisgsqealrelvervske 177
                    GE+ aa++ag ls+e+a++ ++ r+   + ++gp d a+  l        a+e ++l+      +  +a+ ns  +v++sg   a+++     + e
     EEA21220.1 640 GEIGAAYAAGFLSAEDAVRIAYYRGLYGKVASGPNDTAGSMLavgtsmddAKELCELAtmkRYGKFNVAASNSSASVTLSGDVTAIERAKFIFEDE 735
                    *******************9887666555555775555544444448886555566553134567899*******************999999999 PP

                    C.CCEEECCCEECTTCCCCCCCCHHHHHHHH..C.CCHHCHHTTBEHCCCHHH.....HHHCHHHHHHHHHHHCHCCHCCHHTTS...SSECC-CC CS
  Acyl_transf_1 178 gvgalvenvnvavhspqvdaiadalasalad..i.aprkpkvakisstsldes.....serelsaeywvanlrspvrfaeavlsa...aetiplvf 262
                    + ++++ +v+ a hs  +++ a+    a+a   i ++++ k++++ s  l         +++l + yw++nl +pv+f +a+ sa     t p+  
     EEA21220.1 736 QKFVRQLKVDTAYHSHHMQPCAEPYMDAMARikIkVKEPRKSCQWYSSVLGGDlvtteMAQQLAGSYWRDNLLQPVLFSQALESAlekTITPPALA 831
                    999*****************99999998887332244556788887777666668888999************************5333356899* PP

                    EECSSSSCCH CS
  Acyl_transf_1 263 veispHslll 272
                    +e+ pH+ l 
     EEA21220.1 832 IEVGPHPALK 841
                    *******986 PP

>> Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.1   0.0   8.1e-32   7.7e-29       3     116 ..     259     378 ..     258     380 .. 0.92

  Alignments for each domain:
  == domain 1  score: 100.1 bits;  conditional E-value: 8.1e-32
                      EEEEEEEEE--STSSSTSTTHHHHHHHHHHHHHHHT--..GGGEEEEE-SS-SSHHHHHHHHHHHHHHHGGGGG....SCTSEEE-THHHH-B- CS
  Ketoacyl-synt_C   3 vikgsavnsdgahnsltapngeaqaraiekalaeagvd..pedvdyveahgtgtplgDpiElealkkvfgekar....kqplavgSvKsniGHl 90 
                      +i+++++n+dg++ ++t p+  +qa++i++ + +ag+d  +++ +y eahgtgt++gDp+E+ a+ k+f  ++     +++l+vgS+K+ iGH+
       EEA21220.1 259 IIRETGANQDGRTPGITMPSSTSQAQLIQETYTRAGLDieKDRCQYFEAHGTGTKAGDPQEAGAIYKAFFGDKPndptDDNLYVGSIKTVIGHT 352
                      7999******************************998755789*********************9877655555599999************** PP

                      GGGHHHHHHHHHHHHHHHTEE--BTT CS
  Ketoacyl-synt_C  91 eaAaGvaelikvvlalkhgvipptln 116
                      e+ aG+a+l+ + l +khg++pp+l 
       EEA21220.1 353 EGTAGIAGLLRASLGMKHGYVPPNLL 378
                      ***********************985 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       7.6   7.2e+03      64      82 ..    1024    1057 ..     984    1075 .. 0.61
   2 !   65.8   0.0   4.8e-21   4.5e-18       1      99 []    1422    1523 ..    1422    1523 .. 0.88

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 7.6
  Methyltransf_12   64 g.............ssfDlvvasnvlhhl..kdi 82  
                       +              +f lv+++++++++  kd 
       EEA21220.1 1024 NigsevmvtlsnieRKFGLVLCNFTCEACptKDA 1057
                       034444555555556999*********9966332 PP

  == domain 2  score: 65.8 bits;  conditional E-value: 4.8e-21
  Methyltransf_12    1 LeiGcGtGsllrallekl..pdieytgvDispsaiedakeklakrennnn.nnvelealdlldldggssfDlvvasnvlhhlkdirevldni 89  
                       LeiG+GtGs ++a+  +    + +yt++Dis+s+++da+e ++++++++  + +++e +  ++ + +  +Dl+vasnvlh++k ++++l+n+
       EEA21220.1 1422 LEIGAGTGSATEAIMGRVgdNFGSYTYTDISASFFPDAQELFKEHDAKFMyKTLDIEGEPTDQGFTERRYDLIVASNVLHATKFLEKTLKNV 1513
                       8**************999999*************************9875134455555555555559************************ PP

  Methyltransf_12   90 rklLkpgGrl 99  
                       rklL+pgG+l
       EEA21220.1 1514 RKLLRPGGYL 1523
                       ********87 PP

>> KAsynt_C_assoc  Ketoacyl-synthetase C-terminal extension
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.2   0.0   4.5e-18   4.3e-15       2      97 ..     383     488 ..     383     503 .. 0.77

  Alignments for each domain:
  == domain 1  score: 56.2 bits;  conditional E-value: 4.5e-18
  KAsynt_C_assoc   2 npeipaleegrlkVvteptpwpggi......vgvNsfGfGGsnvHviLksnkkekrkeesk....eeslprLlvlsgrteeaveallekleehll 86 
                     np+i+    grl++v+++tpwp+        +++NsfGfGG+n+H+i++++  ++++ +++    ++     +++s+++e++++++l++l ++l+
      EEA21220.1 383 NPDIE-PYYGRLQIVKTATPWPEPPagsprrASINSFGFGGANAHAIIENYAPKTPSATASaeerSSCAAIPFMFSANSEKSLTNQLQSLLSYLE 476
                     78888.788************9988889999*******************996666665554554555666799*******************77 PP

  KAsynt_C_assoc  87 d.aellsllnei 97 
                     d +e+ + l ++
      EEA21220.1 477 DfDEKSTNLRDV 488
                     634444434333 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.3   0.0   5.9e-17   5.6e-14      22     164 ..    1417    1578 ..    1401    1579 .. 0.75
   2 ?    1.3   0.0      0.28   2.7e+02     105     144 ..    1930    1990 ..    1925    1995 .. 0.79

  Alignments for each domain:
  == domain 1  score: 52.3 bits;  conditional E-value: 5.9e-17
  Methyltransf_23   22 aggrvLdiGcGtGillevlren.g..f.svtgvDlspeaveiaekakkaqkdqfdeqeaae................pqgkfdlIvlrevle 93  
                       ++ ++L+iG+GtG+ +e +  + g  f s+t  D+s    + a+       + f e++a++                 ++++dlIv+++vl+
       EEA21220.1 1417 RQLEILEIGAGTGSATEAIMGRvGdnFgSYTYTDISASFFPDAQ-------ELFKEHDAKFmyktldiegeptdqgfTERRYDLIVASNVLH 1501
                       55699********888888443232247*******965333332.......22222222223344444444443333666************ PP

  Methyltransf_23   94 hvpdppellrqiatllkpgGylllseplaslkedrllld.....wlylvpagrhi.sffsarslkelleeaGlevve 164 
                         + ++++l+++++ll+pgGyl+l+e++ +++ ++++       w+   ++gr+   + s + +  +l+++G++ +e
       EEA21220.1 1502 ATKFLEKTLKNVRKLLRPGGYLVLLEITDNDPVRQSFFFgslpgWWVGEEDGRVYsPLLSQHGWDAALRKSGFSGIE 1578
                       ****************************9999999976666777888888877778999**************9876 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.28
  Methyltransf_23  105 iatllkpgGylllseplasl.....................kedrllldwlylvpagrhis 144 
                       +a+ +++++yl+++ep+asl                     +++++l+++++ +++ ++ s
       EEA21220.1 1930 LASQTAEDTYLMVHEPTASLeaslnelardfhvgislttsdSSRSDLKYIHARAHRRTVAS 1990
                       5678899************998888888888888888887667777888888888765555 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       7.6   7.2e+03      58      89 ..    1033    1064 ..    1024    1070 .. 0.76
   2 !   44.4   0.0   2.2e-14     2e-11       1      97 []    1421    1521 ..    1421    1521 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 7.6
                       BSSSTTTEEEEEEESTGGGSSHHHHHHHHHHH CS
  Methyltransf_25   58 lpfedgsfDlvvssgalhhlsdedlekalkei 89  
                       l+  +++f lv+++++ + ++ +d+  ++   
       EEA21220.1 1033 LSNIERKFGLVLCNFTCEACPTKDASPTIFST 1064
                       5666789******9999999988876655444 PP

  == domain 2  score: 44.4 bits;  conditional E-value: 2.2e-14
                       EEEET-TTSHHHHHHHCTST..SSEEEEEESSHHHHHHHHHHHHHTTTTEEEEESBCCGBS....SSTTTEEEEEEESTGGGSSHHHHHHHH CS
  Methyltransf_25    1 vLdlGcGtGrltlalakrlg..kakvtgvDiseemleaareraeeeglnvefvqgdaedlp....fedgsfDlvvssgalhhlsdedlekal 86  
                       +L++G+GtG  t+a+  r+g   +++t +Dis+++   a+e ++e+++++ + + d+e  p    f ++++Dl+v+s++lh ++   lek+l
       EEA21220.1 1421 ILEIGAGTGSATEAIMGRVGdnFGSYTYTDISASFFPDAQELFKEHDAKFMYKTLDIEGEPtdqgFTERRYDLIVASNVLHATK--FLEKTL 1510
                       8*****************95459**********************999999988888554433449**********98899855..799*** PP

                       HHHHHHEEEEE CS
  Methyltransf_25   87 keiarvLkpgG 97  
                       k+++++L+pgG
       EEA21220.1 1511 KNVRKLLRPGG 1521
                       **********9 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.1   0.0   5.4e-14   5.1e-11       1      96 []    1422    1525 ..    1422    1525 .. 0.86

  Alignments for each domain:
  == domain 1  score: 43.1 bits;  conditional E-value: 5.4e-14
                       EEET-TTSHHHHHHH....HTTSEEEEEES-HHHHHHHHHHCCHHT-EEEE....TTEECCCTSS-TT-EEEEEEES-CCC-CCHHHHHHHH CS
  Methyltransf_11    1 LdvGcGtGrlaeala....krgarvvgvDlskemlklakekaseeglkvef....vvadaeklpfednsfDlvvssevlhhvedpekalkei 84  
                       L++G+GtG+ +ea++    +++++++ +D+s+ +   a+e  +e + k+ +    ++++ ++  f +  +Dl+v+s+vlh  + +ek+lk++
       EEA21220.1 1422 LEIGAGTGSATEAIMgrvgDNFGSYTYTDISASFFPDAQELFKEHDAKFMYktldIEGEPTDQGFTERRYDLIVASNVLHATKFLEKTLKNV 1513
                       89*************8554444****************99999999855563333455555789**************************** PP

                       HHHEEEEEEEEE CS
  Methyltransf_11   85 aRvLkpgGllvi 96  
                       +++L+pgG+lv+
       EEA21220.1 1514 RKLLRPGGYLVL 1525
                       *********985 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.4   0.0   1.3e-13   1.2e-10       2     113 ..    1416    1529 ..    1415    1551 .. 0.91

  Alignments for each domain:
  == domain 1  score: 41.4 bits;  conditional E-value: 1.3e-13
  Methyltransf_31    2 dkglrvlDlGCGtGeltfelaeelgpkae.vvGiDiseeaielArenaqklgldnveFeqgdieelekl..ledekfDlilsnevlnaladp 90  
                       ++ l++l++G+GtG  t ++  ++g++   ++  Dis+     A+e  +++  + +  +  die  +++  ++++++Dli++ +vl+a++++
       EEA21220.1 1416 HRQLEILEIGAGTGSATEAIMGRVGDNFGsYTYTDISASFFPDAQELFKEHDAK-FMYKTLDIEGEPTDqgFTERRYDLIVASNVLHATKFL 1506
                       67899********************96444***********************8.88899*****877658899****************** PP

  Methyltransf_31   91 dkileeiervlkpggilliedpr 113 
                       +k+l+++ ++l+pgg+l++ ++ 
       EEA21220.1 1507 EKTLKNVRKLLRPGGYLVLLEIT 1529
                       ******************98876 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.1       1.7   1.7e+03       4      84 ..     633     711 ..     633     730 .. 0.73
   2 !   32.6   0.0   5.5e-11   5.2e-08       7     161 ..    2126    2277 ..    2121    2290 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 1.7
                 EEESTTSH.HHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE- CS
   adh_short   4 lvtGassG.IGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnN 84 
                 +v+G ssG IG a+a  ++++   v ++ ++     +va+  ++++ ++la+ + + d++e+ +l    +k++gk +v   N
  EEA21220.1 633 VVVGHSSGeIGAAYAAGFLSAEDAVRIAYYR-GLYGKVASGPNDTAGSMLAVGTSMDDAKELCELA--TMKRYGKFNVAASN 711
                 689999999*********9999999885544.4555888888888888888888777777776664..35666666665555 PP

  == domain 2  score: 32.6 bits;  conditional E-value: 5.5e-11
                  STTSHHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCSHHHHH CS
   adh_short    7 GassGIGraiakelakeGakvvv.vdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfselseeewe 102 
                  G ++ +G  + + ++++Ga+ vv ++rs++  +++++ + ++ga+++++++D+td+++v++++  +++ l ++  + n+A + ++g +++ s e+++
  EEA21220.1 2126 GLTGDLGISLTRWMVERGARYVVlTSRSPKVDQKWLEGMTALGATVTVLPMDITDEKQVSETYHIIKETLPPVAGVCNGAMVLNDGLIANQSFEDFN 2222
                  6666789999**********9998999999999**************************************************************** PP

                  HHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHH CS
   adh_short  103 rvievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltr 161 
                   ++e  ++g+  l +++ +          +  sS a   +++g+a+Y+A+ ++++++++
  EEA21220.1 2223 GTLEPKVKGTRYLNALFQKP----DLDFFIIFSSLAYTTGNIGQASYAAANGFMVSMAE 2277
                  ****9999998887776655....4456778899999***********99998888876 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.2   0.1   2.1e-10     2e-07       4      65 ..    2414    2477 ..    2411    2478 .. 0.93

  Alignments for each domain:
  == domain 1  score: 31.2 bits;  conditional E-value: 2.1e-10
  PP-binding    4 relvaevlgvplee..idpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaa 65  
                  ++++ ++lg+++e+  i+p t+l +lG+DSl+av++  ++ +e+++++p+  l+   t++++++
  EEA21220.1 2414 VAILYKLLGMSPEDgaISPGTSLIELGIDSLVAVDMRFWFTRELDLDLPVLKLLGGATIEDMVE 2477
                  6788899***8888778********************************************986 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.6   0.0   3.3e-08   3.1e-05       7     144 ..    2132    2268 ..    2126    2277 .. 0.78

  Alignments for each domain:
  == domain 1  score: 23.6 bits;  conditional E-value: 3.3e-08
                    HHHHHHHHHHTT-E.EEEEESSGGHHHHHHHHHHHTTSEE..EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHHHH CS
  adh_short_C2    7 GraiAkalaeeGae.vvltdlneeakkrveelaeelgaev..lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreefdra 98  
                    G  + + + e+Ga+ vvlt ++ + +++  e  ++lga+v  l++D+tde+qv ++   ++e++  + +++n a + ++  g +++ s e+f+ +
    EEA21220.1 2132 GISLTRWMVERGARyVVLTSRSPKVDQKWLEGMTALGATVtvLPMDITDEKQVSETYHIIKETLPPVAGVCNGAMVLND--GLIANQSFEDFNGT 2224
                    677889999****98889999999977777777779988445******************************9999999..************** PP

                    HHHHTHHHHHHHHHHHHHCTSC..CEEEEEEEGGGTSBSTTTTHHHHH CS
  adh_short_C2   99 ldvnlyslfllakaalplmkeg..gsivnlssvgaervvpnynaygaa 144 
                    l+ +++++ +l      l+++      +  ss++ + +  +++ y+aa
    EEA21220.1 2225 LEPKVKGTRYLN----ALFQKPdlDFFIIFSSLAYTTGNIGQASYAAA 2268
                    **9999975543....33333334555555666666666666666655 PP

>> Ubie_methyltran  ubiE/COQ5 methyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0   1.4e-07   0.00013      42     155 ..    1412    1529 ..    1404    1541 .. 0.86

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 1.4e-07
                       H--S--TTEEEEES-TT-HHHHHHHHHHHHHH.EEEEEES-HHHHHHHHHHHHHHTSS...TEEEEE--TTT-TTS-T-EEEEEEES-GGG- CS
  Ubie_methyltran   42 lvavkrgakvlDvagGtgDlafklsdsvgekg.kvvvlDinenmLkvgekklkeegki...nieflqanaeeLpfeddsfDvvtvsfGlrnv 129 
                       l+ ++r  ++l++ +Gtg  + +++  vg+++   +  Di+++ +  +++  ke+  +   +   + ++  +  f++  +D++  s  l  +
       EEA21220.1 1412 LTHKHRQLEILEIGAGTGSATEAIMGRVGDNFgSYTYTDISASFFPDAQELFKEHDAKfmyKTLDIEGEPTDQGFTERRYDLIVASNVLHAT 1503
                       556677889*******************998758999*************999876554444444667777889****************** PP

                       S-HHHHHHHHHHHEEEEEEEEEEEE- CS
  Ubie_methyltran  130 tDklkaLkeayrvlkpGGrlvvlefs 155 
                          +k+Lk++++ l+pGG lv le++
       EEA21220.1 1504 KFLEKTLKNVRKLLRPGGYLVLLEIT 1529
                       ************************86 PP

>> Thiolase_N  Thiolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.2     6e-07   0.00057      75     113 ..     161     199 ..     147     228 .. 0.89

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 6e-07
                 TSEEEEEEHGGGHHHHHHHHHHHHHHTTSHSEEEEEEEE CS
  Thiolase_N  75 evpavtvnkvcsSglkavalaaqsiaageadvvvagGvE 113
                 + p++t++ +csS+l av++a+q+++ ++++ +va G+ 
  EEA21220.1 161 TGPSMTIDTACSSSLIAVHQAVQALRLKQSNLAVAAGAN 199
                 5689********************************985 PP

>> Methyltransf_16  Lysine methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   2.6e-06    0.0025      42     155 ..    1413    1526 ..    1392    1544 .. 0.78

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 2.6e-06
  Methyltransf_16   42 anelsklsvlELGsGtGlvGlavaell..peakviltDleellellkknielnknalkskvkvevLdWgeeleedllekeevDlilaaDcvY 131 
                       +++ ++l++lE+G+GtG    a+   +  +  + + tD++    +     el k  ++ k  +++Ld + e +++ ++++++Dli+a+ ++ 
       EEA21220.1 1413 THKHRQLEILEIGAGTGSATEAIMGRVgdNFGSYTYTDISA--SFFPDAQELFK-EHDAKFMYKTLDIEGEPTDQGFTERRYDLIVASNVLH 1501
                       578899***********988777776533556778888876..45555556644.6899*********99999******************* PP

  Methyltransf_16  132 ledslelLvkvLkellkkesk.vlv 155 
                         + le+ +k +++ll++ +  vl+
       EEA21220.1 1502 ATKFLEKTLKNVRKLLRPGGYlVLL 1526
                       ***9999999999999887665444 PP

>> NodS  Nodulation protein S (NodS)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00023      0.22      46     146 ..    1420    1527 ..    1409    1542 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00023
        NodS   46 dalevGcaaGalte....rlapyckrltvvdvveeaiararervkes.shiswivsdvq.....qfstdekfdlivvaevlyyiedvaelraavrnl 132 
                  ++le+G  +G+ te    r+     + t  d+  +    a+e  ke  ++ ++ + d++     q  t++++dliv ++vl+     + l  +++n+
  EEA21220.1 1420 EILEIGAGTGSATEaimgRVGDNFGSYTYTDISASFFPDAQELFKEHdAKFMYKTLDIEgeptdQGFTERRYDLIVASNVLH---ATKFLEKTLKNV 1513
                  57788777777776211133444567788888888888888877764245677777875222224456789*********86...56678889**** PP

        NodS  133 vsllapdgqlvfGs 146 
                   +ll+p+g+lv+  
  EEA21220.1 1514 RKLLRPGGYLVLLE 1527
                  **********9755 PP

>> DREV  DREV methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.0   0.00058      0.55      92     186 ..    1415    1525 ..    1400    1529 .. 0.78
   2 ?   -3.8   0.0       5.9   5.5e+03     120     145 ..    2299    2324 ..    2297    2327 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00058
        DREV   92 dqedkklldlGaGdGeitkrvaptfee............vyatelsetmrdrlkkkkynvlsa....lelqetdvkldlilclnlldrcfdplklle 172 
                  ++++ ++l++GaG G  t+ +   + +             +  ++ e  +++  k  y+ l +     +   t+ ++dli++ n+l       k l+
  EEA21220.1 1415 KHRQLEILEIGAGTGSATEAIMGRVGDnfgsytytdisaSFFPDAQELFKEHDAKFMYKTLDIegepTDQGFTERRYDLIVASNVLHATKFLEKTLK 1511
                  4567789************999999888999999997774545555556666666666666551112335568889**************9****** PP

        DREV  173 dirsalepngrviv 186 
                  ++r+ l+p g  ++
  EEA21220.1 1512 NVRKLLRPGGYLVL 1525
                  *******9987765 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 5.9
        DREV  120 yatelsetmrdrlkkkkynvlsalel 145 
                  y t    +++drl+k++y  +s+ ++
  EEA21220.1 2299 YITRREANLMDRLEKLGYSNISEWDF 2324
                  6677778899*********9999884 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2558 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       539  (0.030063); expected 358.6 (0.02)
Passed bias filter:                      497  (0.0277205); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              19  [number of targets reported over threshold]
# CPU time: 1.24u 0.31s 00:00:01.55 Elapsed: 00:00:00.49
# Mc/sec: 15653.78
//
Query:       EEA21221.1  [L=326]
Description: alpha-ketoglutarate-dependent 2,4-dichlorophenoxyacetate dioxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.3e-53  181.2   0.2    3.9e-53  181.0   0.2    1.0  1  TauD      Taurine catabolism dioxygenase TauD, TfdA family


Domain annotation for each model (and alignments):
>> TauD  Taurine catabolism dioxygenase TauD, TfdA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  181.0   0.2   2.2e-57   3.9e-53       2     268 .]      11     295 ..      10     295 .. 0.92

  Alignments for each domain:
  == domain 1  score: 181.0 bits;  conditional E-value: 2.2e-57
        TauD   2 vkpltpkfgae..gvdlsdleslddelkeelrellaeygvvvfrgfplspeqqlefarrfG......plygtpgrgtntkygevldvssvyesadianl 92 
                 +kpl+p+fgae  g+d+s++  +++e+++ +r+ la+yg++vfrg +l+++ ++++ar +G         ++ ++++ + ++e+ dvs+ +++++i++ 
  EEA21221.1  11 FKPLHPTFGAEcnGIDFSQP--VSEETVDIIRNGLAKYGILVFRGAELDDARHVALARQLGeldrstVFVMPGQKYRLAPFNELTDVSNIEQDGSIIQ- 106
                 79*****************9..***************************************9999975555556889999*********9***99999. PP

        TauD  93 ayttll.........wHtDlsylesppgiqlLhcleapa..tGGetpfvDgraaynaLpeelpellegltavrvyyhyrg..gglrteqelpavdkhpr 178
                  +++l          +H D sy+++ +g+++L++++ p+   GG t+f+D+r+ay++L++e +e+++   + ++  h+r+  + + +  +  +++k   
  EEA21221.1 107 -KNSLSwqigqgnslFHVDCSYNPRRAGFSVLRAHKLPPkgNGGGTAFADSRTAYDDLDDEKREEIKDYIVCHSLWHSRRlaSPDCEFLKYMEPEKNSM 204
                 .444445678888889***********************7777*************************************8855555556677888999 PP

        TauD 179 tghpvvrthpvltgrkallvnppfatrieglgtpeskelldaleelledpeftyrfqwqe.GdlvifdNrrvlHgrt..afdegeeRhllrcy 268
                 ++h++v+ h++ + r   ++  ++a +++g++ +es+ ++d l ++++++++t+++ w+  Gd+vi+dN++vlH++   +f+ ++ R ++r++
  EEA21221.1 205 ARHKLVQMHEP-SKRMNMYIA-AHAHHFDGWTHQESQPVIDDLMRHVTQDKYTFAVNWENdGDFVIWDNTCVLHRACggDFEGKYIRDMRRAT 295
                 9*********6.*********.*************************************99*****************9**66688****986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (326 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       551  (0.0307323); expected 358.6 (0.02)
Passed bias filter:                      500  (0.0278878); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 2379.11
//
Query:       EEA21222.1  [L=237]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.9e-34  117.0   0.2    8.9e-34  116.7   0.2    1.1  1  adh_short     short chain dehydrogenase
    4.5e-23   82.0   0.2    5.7e-23   81.7   0.2    1.1  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
  ------ inclusion threshold ------
      0.024   14.0   0.0      0.031   13.7   0.0    1.2  1  DUF1776       Fungal family of unknown function (DUF1776)
      0.042   12.4   1.3      0.055   12.0   1.3    1.1  1  AA_permease   Amino acid permease


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.7   0.2     2e-37   8.9e-34      56     189 ..       1     134 [.       1     139 [. 0.95

  Alignments for each domain:
  == domain 1  score: 116.7 bits;  conditional E-value: 2e-37
                 -TTTSHHHHHHHHHHHHHHH.SSESEEEE---SS--SSGGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHH CS
   adh_short  56 vDvtdreevealvekavkkl.gkldvLvnNAGitgsgpfselseeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsK 153
                 +Dvtd  ++++  + + + + g+ld+LvnNAG t+++p+ +ls +++++++evN++gv+ +++a+ + ++ + +G I+n++S a++ ++  ++aY+AsK
  EEA21222.1   1 MDVTDPISIQNCHKIVSELTnGRLDILVNNAGRTHVHPALDLSIQDVRSTFEVNVFGVMAVVAAFSDLLI-RAKGLIINIASLAALTSYVFGSAYCASK 98 
                 799999999999988888889***********************************************99.9*************************** PP

                 HHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHH CS
   adh_short 154 aavagltrslakelaptgirvnavaPGlvdTdmake 189
                 +av++++r+l++el+p g+rv++++ G+v +++ ++
  EEA21222.1  99 GAVVSYSRTLRQELRPLGVRVMVCMVGVVHSNVHNR 134
                 *****************************9988765 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.7   0.2   1.3e-26   5.7e-23      48     177 ..       1     130 [.       1     140 [. 0.95

  Alignments for each domain:
  == domain 1  score: 81.7 bits;  conditional E-value: 1.3e-26
                   --TTSHHHHHHHHHHHHHHH.SSEEEEEE-----EGCSS-GGGH-HHHHHHHHHHHTHHHHHHHHHHHH.HCTSCCEEEEEEEGGGTSBSTTTTHHH CS
  adh_short_C2  48 cDVtdeeqvealveevvekf.gklDilvnnagiapklkgpfletsreefdraldvnlyslfllakaalp.lmkeggsivnlssvgaervvpnynayg 142
                   +DVtd+ +++++ + v e + g+lDilvnnag ++    p+l++s ++++ +++vn+ ++++++ a+   l++++g i+n++s++a  +    +ay+
    EEA21222.1   1 MDVTDPISIQNCHKIVSELTnGRLDILVNNAGRTHV--HPALDLSIQDVRSTFEVNVFGVMAVVAAFSDlLIRAKGLIINIASLAALTSYVFGSAYC 95 
                   6***************99999***************..*******************************888888********************** PP

                   HHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCT CS
  adh_short_C2 143 aaKaalealtrylAvelgpkgiRvNavspgpikTl 177
                   a+K+a+++ +r+l  el p g+Rv +   g+++ +
    EEA21222.1  96 ASKGAVVSYSRTLRQELRPLGVRVMVCMVGVVHSN 130
                   ************************99999998765 PP

>> DUF1776  Fungal family of unknown function (DUF1776)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   6.9e-06     0.031     110     202 ..      41     129 ..      33     180 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 6.9e-06
     DUF1776 110 tiplsswaselnerllspiltlqallplltsrakqkakiivvnpsissslnlpfhapEalvssalsalfevLkrelrphnidvtqikLGnldl 202
                  ++++ ++s+++ +++  ++++ a+  ll         +i+  +s+ +  + +f +      +a+ +  ++L++elrp+++ v+ + +G ++ 
  EEA21222.1  41 DLSIQDVRSTFEVNVFGVMAVVAAFSDLLIR----AKGLIINIASLAALTSYVFGSAYCASKGAVVSYSRTLRQELRPLGVRVMVCMVGVVHS 129
                 57889999*********************95....568888899999999***************************************9875 PP

>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   1.3   1.2e-05     0.055     275     313 ..      60      98 ..      40     107 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 1.2e-05
  AA_permease 275 pfvifikesgvsvlaplinaviltaalssansslysasR 313
                   +v +++ + +++ + +in+++l+a++s++ +s y+as+
   EEA21222.1  60 AVVAAFSDLLIRAKGLIINIASLAALTSYVFGSAYCASK 98 
                  47899999*****************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (237 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       499  (0.027832); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.50u 0.24s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1616.31
//
Query:       EEA21223.1  [L=530]
Description: N-alkane-inducible cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.6e-48  163.6   0.0    1.1e-47  162.9   0.0    1.3  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  162.9   0.0   6.1e-52   1.1e-47      31     434 ..      56     482 ..      21     486 .. 0.86

  Alignments for each domain:
  == domain 1  score: 162.9 bits;  conditional E-value: 6.1e-52
                 HHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHHHHHHHHHTSH..STT.THHHHHHHHHHHHH CS
        p450  31 kkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkklRrfltptltsf..gkl.sleelveeeaedlv 126
                      ++ +kl + +  +  +p  ++++l ++ e+f+    +++++   k+  g++++ a+ge w++ R ++ p +       l  +e+ ++   ++l+
  EEA21223.1  56 TMGRYTWYMKLLGSSNLLTADPANIQALLATQFEHFKTG-APKVMSL--KQMIGRSIFIADGEAWHNARVLMRPLFSREnvSDLtVFEDHFQILLKCLL 151
                 33345788999999999****************999995.4444443..589************************99977777778888888888888 PP

                 HHHHCCCCHCS....EEETHHHHHHHHHHHHHHHHHSSHHHTTTSSH...............HHHHHHHHHHHHHHHHCHHHHCCCCCHHHTCCSCHHH CS
        p450 127 eklrkkagess....elditellskaaldvigsilFgarfdlledek...............lselvkaveelssllskssvqllllfpllkylptkll 206
                 +   +  ++        +++ ++ ++++d  ++i++g+++d+l+++                 +e ++  ++ + +  ++s q+ ++   l+ l + ++
  EEA21223.1 152 QPGTEVDETGRkwtkGASLASFFPCFTIDCATEIFVGRSVDSLKTRLeeviresssihqggeIKEVDTIPKKDFAWAFNRSLQIANVRLRLRSLSSCYG 250
                 7777777776699999****************************99999***99999999997788888888888888999999988887777777666 PP

                 H.HHHHHHHHHHHHHHHHHHHHHHCHCHC.SCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHH CS
        p450 207 r.klkeavkklkdlldklieerretldsa.kksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklreEi 303
                 r +lke+  +l ++++  i+      d+   + ++df++ l ++          +++e+ +++  ll+aG d t+s + +++y++++nP v ekl   +
  EEA21223.1 251 RtELKECKLVLYKFINDAIHAADLAKDQGqVRVKYDFINTLRQNC--------PDHTEVPEQIAGLLAAGRDSTASLMGFVFYHMIRNPMVFEKLLRIV 341
                 5257777778888888888877777766676689********995........799******************************************* PP

                 HHHCCTTT.....T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEETT.........EEE-TT-EEEEEHHHHHT-TTTS.SSTTS--GGG CS
        p450 304 devlgdkr.....eptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirg.........ylipkGtevivnlyalhrdpevf.pnPeeFdpeR 387
                 +e++g ++     ++t++ l + +yl++v +E+LR+ +vvp + ++++ +d+ ++            i+kGte+  ++y lhr+++++ ++++ F+peR
  EEA21223.1 342 RETFGPADddapkRITFETLRSCKYLQNVMNEALRMNSVVP-FNSKCAVRDTMLPTgggadgtkpIYIRKGTEIAYSTYVLHRRKDLWgEDADDFRPER 439
                 ****666669*******************************.999********9844567779999********************************* PP

                 GB-TTSCTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEE CS
        p450 388 FldekgnskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFe 434
                 +++++      +  f PF+ GpR+CiG+++A  e+ +++++lLq F+
  EEA21223.1 440 WEEKRP----ANWHFQPFSGGPRICIGQQFALTEVGYVIVRLLQSFD 482
                 ****86....4799********************************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (530 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       375  (0.0209158); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3609.22
//
Query:       EEA21224.1  [L=277]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
  ------ inclusion threshold ------
      0.043   13.9   1.0        2.5    8.3   0.0    2.5  2  ARL6IP6       Haemopoietic lineage transmembrane helix
      0.064   13.5   0.0      0.091   13.0   0.0    1.2  1  AKAP95        A-kinase anchoring protein 95 (AKAP95)
        0.1   11.7   0.2       0.14   11.2   0.2    1.1  1  NAD_synthase  NAD synthase
        2.2    6.5  14.5      0.038   12.3   7.0    1.7  2  DUF2070       Predicted membrane protein (DUF2070)
        3.6    7.8   9.0       0.38   10.9   2.2    2.6  3  Pox_A14       Poxvirus virion envelope protein A14


Domain annotation for each model (and alignments):
>> ARL6IP6  Haemopoietic lineage transmembrane helix
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.4     0.023        83      28      55 ..     176     203 ..     163     205 .. 0.86
   2 ?    8.3   0.0    0.0007       2.5      34      74 ..     229     268 ..     221     272 .. 0.73

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.023
     ARL6IP6  28 spllaGllvaaFsyglvYlDsavPGvsP 55 
                  pll G+ +++ +  + ++ s+ P   P
  EEA21224.1 176 RPLLYGFACCIPFMVVRFMYSVLPTFIP 203
                 699********999999*****998877 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.0007
     ARL6IP6  34 llvaaFsyglvYlDsavPGvsPPsPfsprskkrfrkeksss 74 
                 ++va ++y  + lD + P ++ P P+s + k++ +k+k ss
  EEA21224.1 229 VIVACYVYIGMRLDELPPELKAP-PLSFKKKDKKKKRKHSS 268
                 68999**************9855.55555555544444443 PP

>> AKAP95  A-kinase anchoring protein 95 (AKAP95)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   2.5e-05     0.091      73     140 ..     209     276 ..     202     277 .] 0.88

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 2.5e-05
      AKAP95  73 ekdvlegvgeehflkkveavhcsaCdlyiPavlssvqkHlksadhnknkrlmkeqlkkesllvaksil 140
                 ++ ++ +v+ + f+  +e +  +aC +yi + l+ +   lk+   +  k+  k+++k++s    ++il
  EEA21224.1 209 YNALFGNVTIYLFMAVLEEIVIVACYVYIGMRLDELPPELKAPPLSFKKKDKKKKRKHSSQDSGENIL 276
                 6677889999**********************************999999999999999877666665 PP

>> NAD_synthase  NAD synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.2     4e-05      0.14      17      49 ..     117     149 ..     102     154 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 4e-05
                   TTSEEEEEE-SSHHHHHHHHHHHHHHTCGEEEE CS
  NAD_synthase  17 gakgvvlGlSGGvDSslvaalavkalgkenvla 49 
                      g+vlG+ GG+ Ss  a l  +al k+ v+ 
    EEA21224.1 117 AIAGLVLGIYGGINSSESADLGTNALLKASVIC 149
                   5689*********************98888775 PP

>> DUF2070  Predicted membrane protein (DUF2070)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.8       0.2   7.1e+02     136     178 ..      17      68 ..       7      77 .. 0.48
   2 ?   12.3   7.0     1e-05     0.038       2     116 ..      96     224 ..      95     240 .. 0.75

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.2
     DUF2070 136 iqpllailllvly.........fspesfllllllslifalavylfivvvdrp 178
                 iq ++++++lv+           ++e  ++l+ +sl+ ++++ + +  +++p
  EEA21224.1  17 IQIFFFAIFLVFGfilchrhgfRRSEGWVILITFSLLRLIGASFQLASINYP 68 
                 2222222222222344555555344444455555555555555555555555 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 1e-05
     DUF2070   2 eklskyifrlPswkvsllliillalligllaflssk............lfgillfglpalvaflltlpvlrilggrltykrslflalltelivviisll 88 
                  +l ky +++++  +s++ ++ +a l+  ++  +++              ++++f+  +++ + l+l +l +l+++++ +r l+  +++ ++++++ ++
  EEA21224.1  96 GRLNKYAKKIHHKAFSVISLVAIAGLVLGIYGGINSsesadlgtnallKASVICFLAAYVAFLGLFLLFLTWLSRIPPNERPLLYGFACCIPFMVVRFM 194
                 68899999999999888887777766555554444459*********77777788888888889999999999999999999**************999 PP

     DUF2070  89 aillsall..qalvllalvlslalvfalrl 116
                  ++l +++   +  ++al+  +++++++ +
  EEA21224.1 195 YSVLPTFIpsIRDNYNALFGNVTIYLFMAV 224
                 999999888844445555555443333333 PP

>> Pox_A14  Poxvirus virion envelope protein A14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.3      0.55     2e+03      15      34 ..      15      34 ..       7      63 .. 0.63
   2 ?    1.8   0.2     0.078   2.8e+02      19      62 ..      82     125 ..      68     128 .. 0.62
   3 ?   10.9   2.2   0.00011      0.38       9      68 ..     108     167 ..     103     176 .. 0.75

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.55
     Pox_A14 15 liaGiiLLilacifafvdfs 34
                 ++ i   ++ ++f f+   
  EEA21224.1 15 AVIQIFFFAIFLVFGFILCH 34
                44444444444555554433 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.078
     Pox_A14  19 iiL..LilacifafvdfskststtdkawralsivsFilgivillgl 62 
                 i L  L+l  i  f  + k  +  +   +a s++s +  + ++lg+
  EEA21224.1  82 IGLapLTLLNIGIFGRLNKYAK--KIHHKAFSVISLVAIAGLVLGI 125
                 4442255666666667777666..4467888888887665566654 PP

  == domain 3  score: 10.9 bits;  conditional E-value: 0.00011
     Pox_A14   9 nyystvliaGiiLLilacifafvdfskstst.tdkawralsivsFilgivillgll.lfsmy 68 
                 + +s + ++ i+ L+l  i+  ++ s s    t+ a+  +s+++F+ + v+ lgl+ lf ++
  EEA21224.1 108 KAFSVISLVAIAGLVLG-IYGGINSSESADLgTN-ALLKASVICFLAAYVAFLGLFlLFLTW 167
                 55677777777777765.6778999999999555.77777**************96256677 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (277 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       845  (0.0471303); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 1822.96
//
Query:       EEA21225.1  [L=1455]
Description: NRPS-like enzyme, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.4e-58  198.5   0.0    2.5e-58  197.7   0.0    1.4  1  AMP-binding    AMP-binding enzyme
    3.6e-11   42.4   0.0    2.9e-10   39.4   0.0    2.2  2  Condensation   Condensation domain
    3.8e-09   37.4   0.1    9.6e-09   36.1   0.1    1.8  1  AMP-binding_C  AMP-binding enzyme C-terminal domain
    8.7e-07   29.2   0.7    2.2e-06   27.9   0.7    1.7  1  PP-binding     Phosphopantetheine attachment site


Domain annotation for each model (and alignments):
>> AMP-binding  AMP-binding enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  197.7   0.0   5.5e-62   2.5e-58       1     422 [.     219     672 ..     219     673 .. 0.82

  Alignments for each domain:
  == domain 1  score: 197.7 bits;  conditional E-value: 5.5e-62
                  HHHHHHHSTTSEEEEE...............CCSTEEEEHHHHHHHHHHHHHHHH.HTTS.STT-E........EEEEESSSHHHHHHHHHHHHTT-E CS
  AMP-binding   1 leeqaaktpdkvalvd...............sgegqtlTYreldervnrlAagLr.slGv.kkgdr........VaillpnspewvvallailkaGav 73 
                  +e+ ++++pd +a+ +               + + + +TY+el++++n+lA  L   l v k++ r        V +l  +spe++va+lailk+G +
   EEA21225.1 219 FEDCVRQHPDNIAVEYlcrtsptsaqrstttTYTRRDVTYAELNAEANELALELGlMLQVlKDKWRpvsgdqyaVPLLILPSPELFVAMLAILKLGHA 316
                  677789999999998889999999999999888899***************9888778884433335555668899********************** PP

                  EEEEETTS-HHHHHHHHHHHTESEEEETCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SS CS
  AMP-binding  74 vvplnptltaeelayiledseakvliatvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTT 171
                   + l ++ + e+l+ i++d +a vl+  v  +      + a+++ea + ++ +d ++++   + ++  ++  +      +++++++d++y++YTSG+T
   EEA21225.1 317 FSSLPSDAPVERLRAIIDDLGAPVLF-GVGPAPW---GDLAGSREAFDGILWVDIASPSAW-RRDFLIDDMPS----LSVRRTSEEDICYLFYTSGST 405
                  **************************.4333332...333444455566788886665543.33333333332....3566799************** PP

                  SS-EEEEEEHHHHHHHHHHHH...HHHCSCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGC.CHHHHHHHHHHHHT-SEEEEEHHHHH CS
  AMP-binding 172 GkPKGVmlshrnlvanvaslk...letrfklkeddvvlsilplahifglilelllallsGatvvllpkdaa.ldpklllelieklkvtviagvPrvle 265
                  GkPKGV   hr++v+ vas     l++   ++++ ++ls    +++  + ++++++l+ G+ v+++++d   +dp+   ++ ++l++t  ++v +++ 
   EEA21225.1 406 GKPKGVLGPHRAAVTCVASTLqgpLSH-LPAGPRLRWLSLSAPSFDPFI-IDTFVPLSIGGVVCVAERDLLlTDPE---ACARELRATASYAVASLAL 498
                  **********99988888865543332.4456799*************7.*******************9977785...6799999********9988 PP

                  HHHHCCCHHCHHHHCCGTT-SEEEEESS-EBHHHHHHHHHHHTC.......EEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTTS CS
  AMP-binding 266 allesgalkaakkakdlsslrlvllggeplspellrffralfge.......evlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeetg 356
                   +  +          +++ l+++++gge++++ ++++f ++ g         ++++YG+TEtt+++t +++ ++ ++ + +G +l  + + +vD++ +
   EEA21225.1 499 LMRPE----------KMPELKTLIVGGESVNSRVIEKFARVHGSthaeddrYLINAYGPTETTIFMT-AEPCTQASRSSIIGDALSSAFCLVVDPDSL 585
                  87444..........4678***********************99******99**************9.7778888899999*9999999999987765 PP

                  CBEE.....TTSEEEEEEEETTS-SEBTT-HHHHHHHEEE.........T.CC.EEEEEEEEE..EETTS..EEEEEEECC.CEEEE CS
  AMP-binding 357 epvp.....dgeeGellvrgpgvmkgYlkkpeataeafds.........e.gr.wlrTGDlgr..ldedG..yleivgRkk.dlikl 422
                     +      g +Gel+v+gp+v++gYl+++++t++af+s         + gr ++rTGD  r  + +dG  ++ ++gR++ d++kl
   EEA21225.1 586 DAGKlrekpFGLSGELVVGGPQVAQGYLNREKETSRAFISacqfpeldlPlGRmLYRTGDKSRvvWSADGkpSIDFLGRIDaDQVKL 672
                  4443222228888**************************8899****9978899******998645799*556*******9677776 PP

>> Condensation  Condensation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.2      0.24   1.1e+03     356     398 ..     891     933 ..     876     939 .. 0.68
   2 !   39.4   0.0   6.5e-14   2.9e-10      38     364 ..    1001    1353 ..     993    1369 .. 0.71

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.24
                   EEESSS-HH.CCCEEECCCCSEEECEE....E.....SSEEEEEE CS
  Condensation 356 fsfenylgq.eseeeesqlselklsvssve.aeeeskydlsleas 398
                   f f n  gq + e+++s+ +  ++s   +  + ee+ y+ls +a+
    EEA21225.1 891 FDFTNENGQhKMETSTSEADNVDVS--AIAiDDEEALYELSNTAK 933
                   6666655664444445555555555..6666799*****997775 PP

  == domain 2  score: 39.4 bits;  conditional E-value: 6.5e-14
                    ---HHHHHHHHHHHHHH-SSCCEEEEE....TTEEEEEE-..TT-----EEEE-T...TSSSHHHH...HHHHHHHHHTC--SCCCS-SEEEEEE CS
  Condensation   38 eldlerlekalqelierhdaLRtvfle..eengepvQvil..eerevelevleis.dleeseeeea...ieefaqkdlqepfdLekgpLfraalf 124 
                    +ld+ r+++a++ +++rhd +Rtvf +  +    +  +il  e++  ++ ++ei  + +++++e+    i + +q+ +++++ ++++      + 
    EEA21225.1 1001 KLDPVRFKRAVNVVLQRHDCFRTVFCNvhHPLFPFAMCILnkESERWKIPTVEIVcNFDNKDNERWqntIASCQQA-AEHSMSMDQAGVTVTWVR 1094
                    6999*********************753122333345666434444444333332133444433334448888885.**********99999999 PP

                    ESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--.......HHHHHHHHHHHHCSHHHHHHHHHHHHHHH......S-- CS
  Condensation  125 kiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktp.......YkdyaeweqqyleskdlekeeaYWseqlegelpvlqLp 212 
                    + + nr+ ++ls+ H i DG+ l+ + + +a+ Y  ++ g++++  q +                +  le  d+ ++  YW ++l g  p+  + 
    EEA21225.1 1095 SADGNRDIMVLSLSHAIYDGIMLSHIREGIATEY--VNPGSTPSGIQGHTdsgtnlaLLPIRATVELLLERGDWTETMFYWMKRLGG-VPNFHIG 1186
                    9999******************************..444444443333322211121222223345578999**************9.7777776 PP

                    -B......SS---SS---S-EEEEEE....EE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEE........EEEEEESSTTCSTCHH CS
  Condensation  213 kd......karpakrsfkadrlsikl....deeteeklrklakeqgvtlndvllaalgllLskytgqddiv........vgteisgReseikdie 289 
                    ++      ++++a++ +++ + + +     + +++e+ ++++++ g+t+ +v +aa+  +L +  +  di         +g+++ gR+ +  d+ 
    EEA21225.1 1187 SKrpvphvERSLAQSGVNEITHMRRSalssSLSMQELSKSATSSLGTTMASVVQAAWVSVLAQTIEAADISsggllhaqFGSIVNGRTTQ--DLW 1279
                    666666655555555555433333334554888999999999********************9999998854444444499*********..*** PP

                    C--SS-EEEEEEEEE--TT-.....BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HH CS
  Condensation  290 rmvGlFvntlPlridvkeak.....tfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgq 364 
                    r v   + t+P+ + ++ +      t  e+ + + ++  +a+p+ ++p  ++      ++ e  +  fd+v++++ y   
    EEA21225.1 1280 RCVAPVLTTVPIHLPLSLGGkkknpTNREVCRMLAAQNTDALPYIDVPCPSV------EMFEMGHARFDTVLNLQAYRSC 1353
                    *************998755423444444777777777777777777777777......3333455679999999888655 PP

>> AMP-binding_C  AMP-binding enzyme C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.1   0.1   2.1e-12   9.6e-09       1      76 []     681     759 ..     681     759 .. 0.81

  Alignments for each domain:
  == domain 1  score: 36.1 bits;  conditional E-value: 2.1e-12
                    HHHHHHHSSTTEEEEEEE-----TTS.---EEEEEE------HHHHHHHHH....HHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   1 evEsalvshpaVaeaaVvGvpdevkG.ealvafVvlkdgsealeeeLkahv....rkelgpyavpkkvvfvdelpktrsGK 76 
                    e+E++l+  ++Va +aVv v+ +  G + l+afV l ++++  e++++a++    ++ l++++ p++  ++++lp t+sGK
     EEA21225.1 681 EIENVLAGAEGVAAVAVVVVKKPGVGsSHLIAFVSLWPDQD--EKDVVARCraqaERLLPHWMSPETYTILNQLPWTASGK 759
                    8**********************666577******943432..3555555522216689999******************9 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.9   0.7   4.9e-10   2.2e-06      10      67 .]     811     868 ..     806     868 .. 0.90

  Alignments for each domain:
  == domain 1  score: 27.9 bits;  conditional E-value: 4.9e-10
  PP-binding  10 vlgvpleeidpdtdlfdlGlDSllavellaaleeefgv.eiplsdlfehptlaelaayl 67 
                 ++g ++ ++dp+t+l +lGlDSl a+ ll +l++  g+  + ls+++   t+++l++++
  EEA21225.1 811 AIGKDVADLDPNTPLLSLGLDSLRAMVLLQRLRDD-GIeVLGLSEVLSSETVRDLTNLV 868
                 6788999****************************.77478999999*******99875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1455 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       457  (0.0254894); expected 358.6 (0.02)
Passed bias filter:                      396  (0.0220871); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.91u 0.33s 00:00:01.24 Elapsed: 00:00:00.51
# Mc/sec: 8512.99
//
Query:       EEA21226.1  [L=134]
Description: 60S ribosomal protein L10 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.3e-20   72.5   0.7    4.3e-20   72.1   0.7    1.1  1  Ribosomal_L16  Ribosomal protein L16p/L10e


Domain annotation for each model (and alignments):
>> Ribosomal_L16  Ribosomal protein L16p/L10e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.1   0.7   2.4e-24   4.3e-20      53     132 .]      10     103 ..       2     103 .. 0.88

  Alignments for each domain:
  == domain 1  score: 72.1 bits;  conditional E-value: 2.4e-24
                    TCCC.CTSXC...EEXXSXXXXEEEEE-.....SS-TTTSSSS....XEEEEEEEEEXSSCEEEEE.TTXXXSHHHHHHHHHHHHTSSSXEEEE CS
  Ribosomal_L16  53 rylk.kkrgk...klwirvfphhpvtkk.....agedRmgkGk....Gkpegwvarvkigqiifei.kagvneeiakealrraasKlpiktkiv 132
                    ry k k+ gk   +l+irv+phh ++++     ag+dR+++G+    Gkp g varvk+g+i++++   + ++ +  +alr   +K+p+++k++
     EEA21226.1  10 RYCKnKTAGKesfHLRIRVHPHHTIRINkmlnvAGADRLQTGMrgawGKPVGKVARVKVGKILVSVrTTDRHRPVTIQALRHSVYKFPGRQKVI 103
                    5555344444667*****************************************************63334999*****************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (134 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       312  (0.017402); expected 358.6 (0.02)
Passed bias filter:                      244  (0.0136092); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.27s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 961.62
//
Query:       EEA21227.1  [L=78]
Description: hypothetical protein PMAA_050450, partial [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.14   11.9   0.8       0.32   10.8   0.7    1.6  2  DUF4597   Domain of unknown function (DUF4597)


Domain annotation for each model (and alignments):
>> DUF4597  Domain of unknown function (DUF4597)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0      0.13   2.4e+03      28      42 ..       8      22 ..       4      26 .. 0.73
   2 ?   10.8   0.7   1.8e-05      0.32      23      48 ..      51      76 ..      43      78 .] 0.88

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.13
     DUF4597 28 tPPtPtgmtlpRDsr 42
                 P t  ++t+p D +
  EEA21227.1  8 KPATEQTLTGPNDWE 22
                577777888888865 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 1.8e-05
     DUF4597 23 PdiiitPPtPtgmtlpRDsrravwlD 48
                P++ + PPtP ++   R+ +r+   D
  EEA21227.1 51 PEMTVIPPTPPSIEALRERNRTTNRD 76
                9999**************99987766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (78 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       334  (0.018629); expected 358.6 (0.02)
Passed bias filter:                      270  (0.0150594); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.29s 00:00:00.68 Elapsed: 00:00:00.45
# Mc/sec: 521.38
//
Query:       EEA21228.1  [L=531]
Description: salicylate hydroxylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.2e-07   28.6   0.0    1.7e-06   27.5   0.0    1.5  1  FAD_binding_3  FAD binding domain
    1.3e-05   24.9   0.0    3.3e-05   23.5   0.0    1.8  2  Cupin_2        Cupin domain


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.5   0.0   1.9e-10   1.7e-06     151     301 ..     361     527 ..     318     528 .. 0.69

  Alignments for each domain:
  == domain 1  score: 27.5 bits;  conditional E-value: 1.9e-10
                    EEEEEEEEEE--GTT-HHHHHHTGG.EEEEEEEEEEEEEEEEEEC..-SCCCTTC....CEEEEECCTTEEEEEECCE.TEEEEEEEEECCE-GGG CS
  FAD_binding_3 151 etvrakYlvGaDGgrStvrktlgie.fegeetvyeagvldvlfda..dlsdivep....lvlilsaesrgvmviPlen.tlerfyvqvearaekee 238
                    ++++ + +vGaDG++S++r +l i+ f++ ++  ++ + +  + +  +++++v++    +++ + +      + P++     +f+++ + +++++e
     EEA21228.1 361 TQIQGDLVVGADGVHSISRTSLHIKpFPSGKSAFRFLLPKQKALDdpETAALVQHigeqNMWFGVDGRI--IMSPTSHnSILNFTIIHPDKESASE 454
                    36999********************98888877566554333222135666666677766666655544..3555555456677777776666666 PP

                    S......CCCHHHHHHHHHHHH...HHTTSSCEEEEEEEEEEEEEEE.EESSSEETTEEE-GGGTEEE-STTS CS
  FAD_binding_3 239 r......sekfteeevkarlre...ivgektldveieevsawtvaqr.vaekyrkgrvflaGDAaHihpPtgG 301
                    +      ++ ++ +++ ++l +   ++ +   +ve+e+v++w++ ++    ++++ r+ l+GDAaH   P  G
     EEA21228.1 455 TagsdtwDQSTNLDKMLKILSSfslAIVKLLSKVEPESVRVWKLIDMdPLPRLNESRLVLIGDAAHPFFPRIG 527
                    52222213333334444444332113344455679********8776268999999**********9999876 PP

>> Cupin_2  Cupin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   0.0   3.7e-09   3.3e-05       2      63 ..      90     150 ..      89     159 .. 0.84
   2 ?   -3.1   0.0      0.74   6.6e+03      15      30 ..     414     429 ..     408     432 .. 0.80

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 3.7e-09
                 EEEEETTEEEEEECSSSEEEEEEEEESEEEEEEC.TEEEEEETTEEEEE-TT-EEEEEE-SSS CS
     Cupin_2   2 lvelppGesapshrHpgedeffyVleGegeltvd.geeveleaGdsvyfpagtpHrfrNtgde 63 
                 +v + p   +p+hr      +++V+eGe+ l++d ge+ ++++Gd+++  + t H++rN+++ 
  EEA21228.1  90 IVDINPDSLSPMHRTVSL-DYGVVIEGEVDLILDsGEVRHMKRGDIAI-QRSTMHAWRNPSKI 150
                 578899889999998888.*************88799********875.66699*****9965 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 0.74
                 CSSSEEEEEEEEESEE CS
     Cupin_2  15 rHpgedeffyVleGeg 30 
                  H ge+ + + ++G++
  EEA21228.1 414 QHIGEQNMWFGVDGRI 429
                 5889999999999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (531 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       418  (0.0233142); expected 358.6 (0.02)
Passed bias filter:                      414  (0.0230911); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 3651.26
//
Query:       EEA21229.1  [L=594]
Description: hydrolase, CocE/NonD family, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.1e-45  153.5   0.0    1.4e-44  152.7   0.0    1.3  1  PepX_C         X-Pro dipeptidyl-peptidase C-terminal non-cata
    3.1e-40  138.5   0.9    4.6e-40  137.9   0.9    1.1  1  Peptidase_S15  X-Pro dipeptidyl-peptidase (S15 family)
     0.0076   15.5   0.0      0.012   14.9   0.0    1.2  1  Hydrolase_4    Serine aminopeptidase, S33


Domain annotation for each model (and alignments):
>> PepX_C  X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  152.7   0.0   2.4e-48   1.4e-44       8     225 ..     343     588 ..     338     589 .. 0.96

  Alignments for each domain:
  == domain 1  score: 152.7 bits;  conditional E-value: 2.4e-48
      PepX_C   8 pvrlqvldggsgs.........twrtedawpspntkattlylsqrgagstgdgtlsaasplsdeaaaseedlydptnpldqdqreeradslafttapla 97 
                 pv + +++g  g+         t+r+e +wp  +t++t+++l        +  +ls+ +pl++  +   ++++++          ++++ l+f+t p++
  EEA21229.1 343 PVSVLLRKGDVGFndaeaekvyTRREEKEWPIGRTQYTKFFLD-------SASSLSTSEPLVKRSEKLSYKALGT---------LDQPELLRFETKPFK 425
                 7888888888888888899999*********************.......***************9999999999.........*************** PP

      PepX_C  98 edtelvGapkakLrvssdap........dadlsvtLvdvdpdGea..........tlitkGwlrlsnRasdeep.................eplePGev 161
                 ++te++G++ a+L+vs+++         d+dl+vtL+ ++p+G++          +++tkGw r+s R++d ++                 ep+  Gev
  EEA21229.1 426 TETEITGHVVAHLNVSVTPYsgsesiptDIDLFVTLRYFGPNGKEvfytgtagdpVPLTKGWQRVSLRKIDSTHyknkpwlphrnytsvdvEPVIIGEV 524
                 ***************************999************7777777777888******************************************** PP

      PepX_C 162 ydleieLqptayrfpkGhrlrlsvsssdfpmilpnpetdtltldlaklkakntvhtgaerpssl 225
                 y++++e++pt+++++kG ++ l+v+s+d++++ +++++d+ +++ +kl ++n++h+g+   ++l
  EEA21229.1 525 YPIDVEIWPTNVVVEKGGKIVLEVASGDTQGAGIFLHNDPVDRSKEKLDGMNHIHFGPHFSNYL 588
                 ***********************************************************99998 PP

>> Peptidase_S15  X-Pro dipeptidyl-peptidase (S15 family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.9   0.9   7.7e-44   4.6e-40       5     238 ..      35     276 ..      33     302 .. 0.86

  Alignments for each domain:
  == domain 1  score: 137.9 bits;  conditional E-value: 7.7e-44
                    EEEEEEEE..TTSSSEEEEEEEESS-CCT.CCCCHTTCHHCCHGGGHH............HHHTT-EEEEEE-TTSTTS-S---TTTTTHHHHHHH CS
  Peptidase_S15   5 LavdiyrPetkskeklPvlltrtPYgkndelasdkalaleelelqdkv............fvarGYavVvqdvrGtggSeGeftvgdsdeaedgad 88 
                    + +++yrP+t++++++Pv++t+ PYgk+ + ++ + ++++e++ +++             +  +GYavV +d rG g+S G+ +++++   +++ d
     EEA21229.1  35 VRANVYRPKTEDGARVPVIVTYGPYGKDIHYKDFHPTSYAEVNPEHHSdhsawetpdpgfWTCNGYAVVRADERGLGQSPGVLDTMSRGTSDAFFD 130
                    679***********************87777777777777777666668899*********************************9********** PP

                    HHHHHHHCTTEEEEEEEEEECHHHHHHHHHCTT--TTEEEEEEECE-S-TCCCCSECTTEEBCCHHHHHHHHHCCCCHHTSSS-STTHHHHHHHHH CS
  Peptidase_S15  89 vidWlakqpwsnGkVgmtGiSYlGttqllaaatgvpalkaivpeaaisdlyddyyregGlvrapgglswedldllaealtsrradegdalkaaary 184
                    v++W+a+qpws+GkVg +GiSY +  q+ +aa+++++l a++p  ++sd y+d  r+gG++   ++  w + ++++++  ++ ++++  +  +   
     EEA21229.1 131 VVEWAAEQPWSTGKVGLLGISYYAGSQWRVAARHPKGLCAMIPWEGMSDYYRDRCRQGGILSNGFIKFWWNRQVTTNQYGRPGRSAR-NWGPNTIE 225
                    ***************************************************************999999666666655555555555.55555555 PP

                    HCHCCCCCCTTHHHTHHHHCCCC--SSSHHHHTT-HHHHHCT--S-EEEEEECC CS
  Peptidase_S15 185 eaasdellaeldrqtpveselletgdydafWkdrnlsedadkvkapvllvgGwn 238
                      + +e la+  ++   e++++++ + +++  ++++   +  +++p+l+v  w 
     EEA21229.1 226 GDLIEEELAANRND-QTEDNASNKFRDEPYYASKEYH--MGDIQVPLLSVANWG 276
                    66666655555555.5788888888888888888887..7**********9996 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0     2e-06     0.012      27     105 ..      95     172 ..      83     210 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 2e-06
  Hydrolase_4  27 LaaqGfavyalDhrGhGrse.gkrghvpsfddyvdDlaafvekvkeehpelplfllGhSmGGliallyllrypdkvagli 105
                  ++ +G+av+  D rG G+s+       + ++d   D+ +   ++++++++ ++ llG S  +    ++++r+p+ + ++i
   EEA21229.1  95 WTCNGYAVVRADERGLGQSPgVLDTMSRGTSDAFFDVVEW--AAEQPWSTGKVGLLGISYYAGSQWRVAARHPKGLCAMI 172
                  6679***************842344455566666666555..45577777799999999999999999999999887777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (594 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       248  (0.0138323); expected 358.6 (0.02)
Passed bias filter:                      228  (0.0127168); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 3953.02
//
Query:       EEA21230.1  [L=134]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.12   12.4   0.0       0.18   11.9   0.0    1.3  1  DUF3122   Protein of unknown function (DUF3122)


Domain annotation for each model (and alignments):
>> DUF3122  Protein of unknown function (DUF3122)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   9.9e-06      0.18      40      62 ..      11      33 ..       6      64 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 9.9e-06
     DUF3122 40 geekeleLrlvgfpgsveldhpq 62
                 +e++ +Lr+vg+p ++e++h++
  EEA21230.1 11 TTENQARLRVVGYPSEYEVHHSN 33
                567899***************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (134 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       276  (0.0153941); expected 358.6 (0.02)
Passed bias filter:                      227  (0.0126611); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.36u 0.26s 00:00:00.62 Elapsed: 00:00:00.39
# Mc/sec: 1030.61
//
Query:       EEA21231.1  [L=1308]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.7e-37  129.4   0.2      3e-37  128.6   0.2    1.3  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    1.7e-07   31.0   0.0    4.3e-07   29.7   0.0    1.6  1  gag_pre-integrs  GAG-pre-integrase domain
    0.00047   20.3   0.0     0.0011   19.1   0.0    1.7  1  rve              Integrase core domain
     0.0068   15.9   0.0      0.013   15.0   0.0    1.4  1  RVT_1            Reverse transcriptase (RNA-dependent DNA pol
  ------ inclusion threshold ------
      0.068   13.1   0.0       0.16   11.9   0.0    1.6  1  Flg_hook         Flagellar hook-length control protein FliK
        0.1   12.9   3.2       0.27   11.5   3.2    1.7  1  Orthopox_F14     Orthopoxvirus F14 protein


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  128.6   0.2   9.9e-41     3e-37       9     234 ..     812    1034 ..     803    1040 .. 0.91

  Alignments for each domain:
  == domain 1  score: 128.6 bits;  conditional E-value: 9.9e-41
       RVT_2    9 PkdrkaigsrWvftkkkddl.kevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeeelvvhqldvdsafLnaeldeevyvkqPpGfe 104 
                   k+++ +   W++  k+d++ + vk karlv++G  q    d  +++a  +   s r ++a+aa  +l + q d   af+na+ldee++++  pG+ 
  EEA21231.1  812 AKGKQILDCMWIYVYKQDKKgRLVKCKARLVVRG-DQEKRDDMRDTYAATLAARSFRTFMAIAARFDLELKQYDAVNAFVNAKLDEEIFMRMAPGYR 907 
                  577888999********999899***********.577889******************************************************96 PP

       RVT_2  105 idreeekvykLnkslyGlkqapllWnekidkvLkklgferseaesGlyvrgtgegklivalyvddlliagsdikil..edvkkelakkfklkdlgkv 199 
                     e++k+y+Lnk+lyGl+++pllW+++++++L klgf+  + e    +++     +++  y+dd+++a ++++ l  + + ++l +k++++   ++
  EEA21231.1  908 ---ESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFRAVPHEPCCMLKS----GVMLFFYMDDIVVAYKKSRQLeaNSILNQLRAKYNISGGEDL 997 
                  ...46****************************************999999....78999*********9999877225799*************** PP

       RVT_2  200 skfLGieiaq..eaggiklsladyiakvvkkfeltda 234 
                  + fLG+ i++  ++  i ls+a yi k++k ++ ++a
  EEA21231.1  998 EWFLGMRIIRdrSNKMIWLSQATYIDKIAKLADTQQA 1034
                  ********986568889***********998876655 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.7   0.0   1.4e-10   4.3e-07      19      66 ..     163     214 ..     146     215 .. 0.76

  Alignments for each domain:
  == domain 1  score: 29.7 bits;  conditional E-value: 1.4e-10
  gag_pre-integrs  19 knkssinlWHrRLGHpsfsrlkkLfkkgl...lpglkisk.sevCeaCqlgK 66 
                        k ++n+WH RLGHp+ + lk+L+       l g++++    +Ce+C  +K
       EEA21231.1 163 ERKADANRWHARLGHPGPEVLKHLAGAAKgvrLTGISKGPtTVECESCGTSK 214
                      35899********************8544334555554433559****9988 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   3.8e-07    0.0011       2     116 ..     228     344 ..     227     346 .. 0.86

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 3.8e-07
         rve   2 trpgelwqvDvtvvripdgggkayllvvvddfsrlilaealsdemdastvlalleravarfggve...pervlsDngseytskafrefla.dlgirvsf 96 
                 ++pge++ +D+  ++ ++  g++ l  ++d fs++++ ++++++   + +l++l+ +++++ +     p ++ +Dn  + +  +++ +l+ + +i +++
  EEA21231.1 228 HAPGEHLAIDFHDFAESTMHGEKTLMLITDRFSGFMWDYYMTSH-RGDEILETLKWFLDYLEKAYmisPVKIEMDNEIAKRP-EVKHYLEhEKRIILQP 324
                 89**********777799999***********************.**********99999999879**********976664.5555555157899999 PP

         rve  97 trpgrpqdnGkvErfhrtlk 116
                 ++++    nG +Er   ++k
  EEA21231.1 325 SPAHTQALNGGAERSGAIIK 344
                 99999999999999876666 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   4.5e-06     0.013     117     185 ..     901     983 ..     872     993 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 4.5e-06
                 .........TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T................TEEECTTEEEEEESSHHH..HHHHHH CS
       RVT_1 117 rv.nge.eskgryekkglpqGsvlSPllfnlfmnellrelrkra..........kgvtllrYaDDililskskee..lqelle 185
                 r+  g  es+++y+ +    G+  SPll++  +++ l +l  ra          +gv l  Y+DDi++++k+  +  ++++l+
  EEA21231.1 901 RMaPGYrESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFRAvphepccmlkSGVMLFFYMDDIVVAYKKSRQleANSILN 983
                 44344447899999999999***************9999999999***************************88844444454 PP

>> Flg_hook  Flagellar hook-length control protein FliK
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   5.4e-05      0.16      34      69 ..    1194    1229 ..    1186    1245 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 5.4e-05
                  ETTEEEEEEEE-SCHHHHHHHHTHHHHHHHHHCCTT CS
    Flg_hook   34 rggqlsvqltaenpetrelLeqnlprLreaLaaaGl 69  
                  r +  ++++  +n++t+ lLe+++prLr+ L+   +
  EEA21231.1 1194 RFQTPTLHVYCDNQQTLGLLEKDAPRLRTKLRHVDI 1229
                  55566899**********************987544 PP

>> Orthopox_F14  Orthopoxvirus F14 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   3.2   9.2e-05      0.27      32      70 ..     491     528 ..     480     531 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 9.2e-05
  Orthopox_F14  32 idedditellniltelGcdvdfdedfsdiaddvleslie 70 
                   +  ++it ll  l +lG d dfd++++d+ d + + +++
    EEA21231.1 491 VSTQEITRLLTKL-DLGTDADFDDEYADLIDHITDVVFD 528
                   5667888888776.79***************99887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1308 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       553  (0.0308439); expected 358.6 (0.02)
Passed bias filter:                      511  (0.0285013); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.83u 0.31s 00:00:01.13 Elapsed: 00:00:00.49
# Mc/sec: 8091.93
//
Query:       EEA21232.1  [L=455]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.081   13.3   3.5        3.6    8.1   0.3    2.5  2  REV1_C           DNA repair protein REV1 C-terminal domain
        2.1    8.1   6.1       0.58    9.9   0.2    2.6  3  Sulfotransfer_4  Sulfotransferase domain


Domain annotation for each model (and alignments):
>> REV1_C  DNA repair protein REV1 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.2    0.0024        21      43      82 ..     147     186 ..     122     188 .. 0.85
   2 ?    8.1   0.3    0.0004       3.6      16      81 ..     206     269 ..     199     278 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0024
      REV1_C  43 avavlkwlrvlleeeeeskeeeageaWekafrevkeavqe 82 
                 ++++  w+++ +  + +++   ++ +W++a+ ++ke+v++
  EEA21232.1 147 IEQIFIWMKQTVSPSYHKTCIAVTANWKEAYINLKEQVNQ 186
                 45677799999998888999999***************96 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0004
      REV1_C  16 egPneeDvealakyLkkvv..eeerdlekavavlkwlrvlleeeeeskeeeageaWekafre.vkeavq 81 
                  +P  +D+ea  +  ++++  +e + +  a +vl w  + l+       +  ++aW +a++  ++e+++
  EEA21232.1 206 LKPSTRDLEAWITKWEELLleAERKSMVIADDVLDWSTRFLDAI-----RPLDDAWTTAYEItIEEKIE 269
                 57999*****99999999988888********************.....9**********853666665 PP

>> Sulfotransfer_4  Sulfotransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.3     0.066   5.9e+02     125     172 ..     140     185 ..     121     207 .. 0.54
   2 ?    9.9   0.2   6.5e-05      0.58      97     175 ..     210     293 ..     208     299 .. 0.77
   3 ?   -1.9   0.0      0.26   2.4e+03     143     174 ..     378     411 ..     350     446 .. 0.65

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.066
  Sulfotransfer_4 125 lldpllellaklvellralvrrlfgagsdaedeeaakeayeehnervr 172
                      + ++ +++ ++++ +++++v+  ++++    +++++keay + +e+v 
       EEA21232.1 140 WSEQ-KKAIEQIFIWMKQTVSPSYHKT-CIAVTANWKEAYINLKEQVN 185
                      4433.4444555555555555555553.33555555555555555554 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 6.5e-05
  Sulfotransfer_4  97 eRdpekWlksmkktllalrsetls...rllalldpllellaklvellralvrrlfgag.s.daedeeaakeayeehnervrevv 175
                      +Rd e+W ++++++ll++ ++ +     +l + +++l++ ++l +++ ++++  ++++    + +++++++a+++  +++r+  
       EEA21232.1 210 TRDLEAWITKWEELLLEAERKSMViadDVLDWSTRFLDAIRPLDDAWTTAYEITIEEKiEdGTLTRRELANAFRRNLRKIRNRR 293
                      8**************999988554344788888889999999999999999999888754234566777777777777777655 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 0.26
  Sulfotransfer_4 143 lvrrlfgag.s.daedeeaakeayeehnervrev 174
                      l+++l  ++   ++  + +ak++ e+h + v+++
       EEA21232.1 378 LFKNLAPEEfIpRWGPRMRAKKFAEDHPDLVKKI 411
                      4443333332234566667777777777777664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (455 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1145  (0.063863); expected 358.6 (0.02)
Passed bias filter:                      461  (0.0257125); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 2945.23
//
Query:       EEA21233.1  [L=426]
Description: monoxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.4e-18   66.0   4.4    6.2e-17   61.9   4.4    2.6  1  FAD_binding_3   FAD binding domain
    5.5e-07   29.1   0.7    3.5e-06   26.5   0.2    2.1  3  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    2.4e-06   27.7   0.2      8e-06   26.0   0.2    1.8  2  NAD_binding_8   NAD(P)-binding Rossmann-like domain
    5.1e-06   26.3   1.6    1.1e-05   25.2   0.9    1.8  2  DAO             FAD dependent oxidoreductase
    6.7e-06   25.2   0.8      0.039   12.8   0.3    2.5  2  Trp_halogenase  Tryptophan halogenase
    0.00012   21.3   0.7    0.00021   20.5   0.7    1.3  1  FAD_binding_2   FAD binding domain
    0.00061   19.2   0.7       0.62    9.3   0.1    2.3  2  AlaDh_PNT_C     Alanine dehydrogenase/PNT, C-terminal domain
    0.00073   18.9   0.6     0.0013   18.0   0.2    1.6  2  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
     0.0021   16.8   0.5     0.0045   15.7   0.2    1.6  2  HI0933_like     HI0933-like protein
     0.0079   16.7   0.1      0.017   15.7   0.1    1.6  1  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
      0.026   13.6   1.7       0.69    8.9   1.6    2.7  2  Lycopene_cycl   Lycopene cyclase protein
      0.031   13.6   0.4      0.066   12.5   0.4    1.5  1  FAD_oxidored    FAD dependent oxidoreductase
      0.056   12.7   0.2        0.1   11.8   0.2    1.3  1  Thi4            Thi4 family
      0.067   12.3   0.2       0.13   11.4   0.1    1.5  2  GIDA            Glucose inhibited division protein A
       0.18   11.8   0.5        2.2    8.3   0.4    2.6  2  NAD_binding_9   FAD-NAD(P)-binding
       0.23   10.7   0.5         10    5.3   0.1    2.5  3  Amino_oxidase   Flavin containing amine oxidoreductase


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.9   4.4   5.5e-20   6.2e-17       3     315 ..       6     336 ..       4     342 .. 0.70

  Alignments for each domain:
  == domain 1  score: 61.9 bits;  conditional E-value: 5.5e-20
                    EEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSSS--EEEHHHHHHHHH.TT-HHHHHHHSEECCCCEEEEEEECCCCCEEEEEHH.CHHCS CS
  FAD_binding_3   3 dVlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlpradglnqrtmellrq.lGledrilaegapnelmgealynelsdtpkaradle.lessp 96 
                    +++IVG+G aGl +a  L+    + +++e+ s + + +    l++    + ++   l ++++++g+  +  g+ +yn  ++  + r+ l+  e  +
     EEA21233.1   6 NIIIVGGGIAGLATAIALRASNRKITILEQSSLNREIGAIISLQPNASKIVEKtWDLGNTLKDKGSMAD-EGFQVYNL-NGELQMRIPLStTEKYG 99 
                    689******************899999999999888888888899988888752589999999997766.68888888.33334444444335666 PP

                    T-CEE--HHHHHHHHHHHHHHH.....TEEETCSEEEECCEECCCCCCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHHH.....TGGEEEEEEE CS
  FAD_binding_3  97 ervtvypqteleriLvehaeer.....glqvrfktevesleqdeegvtaevrdketgeeetvrakYlvGaDGgrStvrktl.....giefegeetv 182
                     +  +y   +l  +L ++a+++     +++++ + +v+      + ++  v + +tge+  ++a+ ++GaDG +S vr+++     +  ++g++  
     EEA21233.1 100 AERMLYHRIDLHDALKKRATSEewpgePAEIHVSSRVT----RCDCEEG-VVYTQTGEK--FQADLIIGADGIKSVVRDSVldtkvPALRTGHSAY 188
                    66678888889999998888862221134444444444....3333344.444557877..*****************975322113335666654 PP

                    EEEEEE.EEEEEC.-SCCCTTC...CEEEEECCTTEEEEEECCETEEEEEEEEECCE-GGGSCCCHHHH.........HHHHHHHHHHTTSSCEEE CS
  FAD_binding_3 183 yeagvl.dvlfda.dlsdivep...lvlilsaesrgvmviPlentlerfyvqvearaekeersekftee.........evkarlreivgektldve 264
                      +  + ++l+d   + d+v+p    + +  a++r + ++P +n+++  +v +  +++ +e++++++++         e  a+ +e    +   v+
     EEA21233.1 189 RMILPVdKLLADCkAFCDVVDPqapYTTMVMAHNRRMIMGPARNGSVYSIVAMVPDEDMNEDPTNTSWTthgdipkmkETFADFPEWARGPLSCVN 284
                    333333134444466666777799877788888888899*****99999***********999998886111111111233333333334444455 PP

                    EEEEEEEEEEEE.EESSSEETTEEE-GGGTEEE-STTSHHHHHHHHHHHHHH CS
  FAD_binding_3 265 ieevsawtvaqr.vaekyrkgrvflaGDAaHihpPtgGqGlNtaiqDavnLa 315
                      ev  w++++     +++kgrv+l+GDAaH++ Pt+GqG   ai+Da  ++
     EEA21233.1 285 DGEVGLWQLRDIgPLPTWTKGRVMLVGDAAHAMLPTQGQGASQAIEDAEAVG 336
                    56777888888624789*******************************8877 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.5   0.2   3.1e-09   3.5e-06       2      58 ..       6      93 ..       5     167 .. 0.69
   2 ?    0.5   0.0      0.26   2.9e+02     199     238 ..     129     166 ..     125     178 .. 0.84
   3 ?   -1.9   0.0       1.4   1.6e+03      25      79 ..     306     371 ..     301     390 .. 0.59

  Alignments for each domain:
  == domain 1  score: 26.5 bits;  conditional E-value: 3.1e-09
                 SEEEE--SHHHHHHHHHHHHHTS-EEEEE......TTHCHHHCSHHHHCHHHHHHHHHHHHH.........................H CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxxxxxx.........................x RF
  Pyr_redox_2  2 dvvviGgGpAGlaaaltlaqagakvtlve......legtclnggcllskallgvaedaeias.........................e 58
                 +++++GgG+AGla+a+ l++++ k+t++e      + g++   ++  sk+++++ + +++++                          
   EEA21233.1  6 NIIIVGGGIAGLATAIALRASNRKITILEqsslnrEIGAIISLQPNASKIVEKTWDLGNTLKdkgsmadegfqvynlngelqmriplS 93
                 79**************************988988888889999999999999999999988888888887777666666666666662 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.26
                  EEEESCEEEEEEETTEEEEEEETTSCEEEESEEEE-S-EE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 199 evklgtsvkeidgngeklevvledgeeidadlvvvavGvr 238
                  e+++ ++v++ d ++    v +++ge+++adl++ a G++
   EEA21233.1 129 EIHVSSRVTRCDCEEG--VVYTQTGEKFQADLIIGADGIK 166
                  5778888888888777..688999999******9999976 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 1.4
                  -EEEEE..TTHCHHHCSHHHHCHHHHHHHHHHHHH.........HHHHCHHHHCCCCHCCTCEEEE CS
                  xxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxx.........xxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  25 kvtlve..legtclnggcllskallgvaedaeias.........evvkklnqgielllgeevvkid 79 
                  +v+lv+  +  +++++g   s+a++ +++ +   +         e++k +n++i     + +++i 
   EEA21233.1 306 RVMLVGdaAHAMLPTQGQGASQAIEDAEAVGTFYAdididkdglEQIKAVNEKIFQCRYKRATTIQ 371
                  566665555555666666666666666666654446777777776667777665544444566654 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0   0.2   7.1e-09     8e-06       1      28 [.       9      36 ..       9      40 .. 0.96
   2 ?   -3.1   0.0       8.8   9.9e+03      24      34 ..      55      65 ..      51      83 .. 0.63

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 7.1e-09
                   EE--SHHHHHHHHHHHCCTEEEEEE-SS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekr 28
                   IvG+G++Gl++A +L+  ++++++le++
     EEA21233.1  9 IVGGGIAGLATAIALRASNRKITILEQS 36
                   9*************************86 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 8.8
                   EE-SSSSSSGG CS
  NAD_binding_8 24 llekrdrlGGr 34
                   ++ek ++lG  
     EEA21233.1 55 IVEKTWDLGNT 65
                   77888888833 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   0.9   9.7e-09   1.1e-05       2      29 ..       7      36 ..       6      47 .. 0.85
   2 ?   -1.3   0.0       1.1   1.3e+03     165     222 ..     132     183 ..     109     282 .. 0.53

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 9.7e-09
                EEEECTSHHHHHHHHHHHHTT..EEEEESS CS
         DAO  2 vviiGGGiiGlstAyeLarrg..Vtllekg 29
                ++i+GGGi+Gl+tA +L + +  +t+le++
  EEA21233.1  7 IIIVGGGIAGLATAIALRASNrkITILEQS 36
                9****************444468*****98 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.1
                 ESECEEEEEEEETCEEEEEEECT.EEEEEEEEEEE--GGGHHHH.HTT.CTTTSEEEEEEE CS
         DAO 165 egtevtgleeedgkvwgverttp.gendaadavVnaaGawsdll.gll.keldlpispvrg 222
                   ++vt+ + e     gv + t+ ge+++ad ++ a G+ s  + +    + ++p   +r 
  EEA21233.1 132 VSSRVTRCDCE----EGV-VYTQtGEKFQADLIIGADGIKS--VvRDSvLDTKVPA--LRT 183
                 45556655333....333.2344477755577888888876..3222222222222..222 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.8   0.3   3.5e-05     0.039       1      36 [.       6      38 ..       6      57 .. 0.87
   2 !   10.6   0.0   0.00017      0.18     190     255 ..     146     222 ..      93     362 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 3.5e-05
                    EEEEE--SHHHHHHHHHHHHHTTTSSEEEEEE-SSS CS
  Trp_halogenase  1 kivivGGGtaGwlaAaalakalkgklevtlveseei 36
                    +i+ivGGG+aG  +A+al+       ++t++e++ +
      EEA21233.1  6 NIIIVGGGIAGLATAIALRASN---RKITILEQSSL 38
                    69****************9998...56999998766 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00017
                     EEETTS-EEE-SEEEE-SGGG-IIIIIIT-.......--EEE-TTT----EEEE...EEEE--H---SSEE.EEE-S CS
  Trp_halogenase 190 lrledgreveadlfiDcsGfrgllieqaLk.......tgfedwsdvLltdrAla...vqveseelvepytr.ataek 255
                     + +++g++++adl+i + G ++ + +++L+       tg   +  +L++d+ la   + ++ +++ +pyt+ ++a++
      EEA21233.1 146 VYTQTGEKFQADLIIGADGIKSVVRDSVLDtkvpalrTGHSAYRMILPVDKLLAdckAFCDVVDPQAPYTTmVMAHN 222
                     34455******************9999876111111156677888999**999843345566668899998666766 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5   0.7   1.9e-07   0.00021       2      32 ..       7      37 ..       6      44 .. 0.93

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 1.9e-07
                   EEEE--SHHHHHHHHHHHHTTT-EEEEESSS CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGlkvavvekeq 32
                   +i++G+G+AGLa A++++  ++k++++e+ +
     EEA21233.1  7 IIIVGGGIAGLATAIALRASNRKITILEQSS 37
                   79**************************976 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.1   0.00056      0.62      30      60 ..       6      36 ..       2      50 .. 0.87
   2 !    8.0   0.1    0.0014       1.5      37      91 ..     322     376 ..     299     379 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00056
                 EEEEESTSHHHHHHHHHHHHTT-EEEEEESS CS
  AlaDh_PNT_C 30 kvlviGgGvaGlqAiatakglgakVtvlDvr 60
                 +++++GgG+aGl+ + + ++ + k+t+l+ +
   EEA21233.1  6 NIIIVGGGIAGLATAIALRASNRKITILEQS 36
                 689**********999999999999999876 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0014
                  SHHHHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTTCECEEHCHHHHHHHHHHHH CS
  AlaDh_PNT_C  37 GvaGlqAiatakglgakVtvlDvrparleqleslgakfvevlksqeellaeavke 91 
                  G    qAi+ a ++g     +D++++ leq++++++k+++ +++ + ++++  ++
   EEA21233.1 322 GQGASQAIEDAEAVGTFYADIDIDKDGLEQIKAVNEKIFQCRYKRATTIQQYSRQ 376
                  55578**************************************999999987665 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.2   1.2e-06    0.0013       1      32 [.       8      38 ..       8      65 .. 0.87
   2 ?   -3.4   0.0       3.8   4.3e+03     112     133 ..     142     164 ..     127     165 .. 0.53

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 1.2e-06
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEkgni 32
                 iI+G+G aGla+ai+l+ ++  +++ilE+ ++
   EEA21233.1  8 IIVGGGIAGLATAIALRASNR-KITILEQSSL 38
                 8*******************9.79****9865 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 3.8
  Pyr_redox_3 112 egfevet.sketyeAkkviiAtG 133
                  e+ +v t + e+++A+ +i A G
   EEA21233.1 142 EEGVVYTqTGEKFQADLIIGADG 164
                  33334440445888888887766 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.2     4e-06    0.0045       2      32 ..       6      36 ..       5      44 .. 0.91
   2 ?   -2.2   0.0       1.1   1.3e+03     125     167 ..     129     168 ..     117     170 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 4e-06
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SS CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVllleka 32
                 ++i++GgG AGl +Ai++++ ++++++le+ 
   EEA21233.1  6 NIIIVGGGIAGLATAIALRASNRKITILEQS 36
                 79***************************86 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.1
                  EEE-S--EEEEECETTE.EEEEE.TTEEEEESEEEE----SS- CS
  HI0933_like 125 klrletevksvekeedgkfrvktkseeeleadklvlAtGGlSi 167
                  +++++++v++ + ee g   v t+++e+++ad ++ A G +S+
   EEA21233.1 129 EIHVSSRVTRCDCEE-G--VVYTQTGEKFQADLIIGADGIKSV 168
                  778888888885533.3..355557999***999999998886 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.1   1.5e-05     0.017       1      32 [.       6      37 ..       6      56 .. 0.90

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 1.5e-05
                EEEEECSSHHHHHHHHHHHHTTSEEEEEESSS CS
   Pyr_redox  1 kvvvvGgGyiglElAgalaelgkkVtvversd 32
                ++++vGgG  gl  A al++ + k+t++e s+
  EEA21233.1  6 NIIIVGGGIAGLATAIALRASNRKITILEQSS 37
                589*************************9886 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   1.6   0.00062      0.69       2      34 ..       7      37 ..       6     185 .. 0.58
   2 ?   -0.3   0.0      0.39   4.4e+02     251     288 ..     300     337 ..     283     373 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00062
  Lycopene_cycl  2 vvviGaGpAglslAarlteakpglkvvlieasp 34
                   ++++G+G Agl+ A  l   + + k++++e s 
     EEA21233.1  7 IIIVGGGIAGLATAIAL--RASNRKITILEQSS 37
                   89**********99999..55556666666553 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.39
  Lycopene_cycl 251 lprleqkvlaiGaaaglvhPaTGYsvarslaeapllas 288
                    +  ++ +v+ +G aa ++ P+ G    +++  a+ +  
     EEA21233.1 300 PTWTKGRVMLVGDAAHAMLPTQGQGASQAIEDAEAVGT 337
                    44466779***************999999988886554 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.4   5.9e-05     0.066       2      31 ..       7      36 ..       6      38 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 5.9e-05
  FAD_oxidored  2 vvVvGGgpaGvaAAiaAaraGakvlLveer 31
                  +++vGGg+aG+a Aia   + +k  ++e++
    EEA21233.1  7 IIIVGGGIAGLATAIALRASNRKITILEQS 36
                  89***********************99986 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.2     9e-05       0.1      19      50 ..       6      36 ..       2      45 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 9e-05
                EEEEE--SHHHHHHHHHHHHCTTS-EEEEESS CS
        Thi4 19 DvvivGaGssGLtaayylakkpdlkvailers 50
                +++ivG+G +GL++a  l  + + k++ile+s
  EEA21233.1  6 NIIIVGGGIAGLATAIALRAS-NRKITILEQS 36
                79*************999888.9*******86 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1   0.00011      0.13       2      30 ..       7      35 ..       6      72 .. 0.83
   2 ?   -3.1   0.0       2.8   3.1e+03     130     149 ..     145     164 ..     126     187 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00011
                EEEE-SSHHHHHHHHHHHHTT--EEEEES CS
        GIDA  2 viViGgGhAGceAAlaaarlGakvlLith 30
                +i++GgG AG++ A+a+  ++ k++++ +
  EEA21233.1  7 IIIVGGGIAGLATAIALRASNRKITILEQ 35
                89***************999999988833 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 2.8
                 EEEETTS-EEEECEEEE--T CS
        GIDA 130 gvvtedgetikakavviatG 149
                 +v+t++ge+++a+ ++ a G
  EEA21233.1 145 VVYTQTGEKFQADLIIGADG 164
                 48999999999999998877 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   0.4    0.0019       2.2       2      34 ..       9      36 ..       8      46 .. 0.81
   2 ?   -0.2   0.0      0.78   8.8e+02     119     152 ..     131     162 ..     116     165 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.0019
  NAD_binding_9  2 ivGaGprGlavlerLlarakkkspleitlfdps 34
                   ivG+G++Gla++ +L a++      +it+ ++s
     EEA21233.1  9 IVGGGIAGLATAIALRASN-----RKITILEQS 36
                   9**************9985.....566666665 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.78
  NAD_binding_9 119 vhraevvdleeradgqavlladgaslaadaVvLA 152
                    +++++v++++++++   v +++g++++ad ++ A
     EEA21233.1 131 HVSSRVTRCDCEEG--VVYTQTGEKFQADLIIGA 162
                    56789999998866..47889999***9999866 PP

>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.1    0.0092        10       1      23 [.      14      36 ..      14      38 .. 0.94
   2 ?    2.9   0.0     0.047        53     222     257 ..     127     160 ..     112     168 .. 0.85
   3 ?   -2.8   0.0       2.6   2.9e+03     392     432 ..     274     317 ..     273     327 .. 0.77

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0092
                   HHHHHHHHHHHHTTEEEEEEESS CS
  Amino_oxidase  1 laGLaaArqLlsaGfdVtvlEar 23
                   +aGLa+A  L + ++++t+lE +
     EEA21233.1 14 IAGLATAIALRASNRKITILEQS 36
                   8********************76 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.047
                    TEEEETSEEEEEEEEETTCEEEEETTSTEEEESEEE CS
  Amino_oxidase 222 gldirlntrVkeikregdgvtvtledgevveaDaVv 257
                    + +i++++rV++ +   ++  v +++ge+++aD ++
     EEA21233.1 127 PAEIHVSSRVTRCDC--EEGVVYTQTGEKFQADLII 160
                    568999999999998..444566789*******998 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 2.6
                    TTTSSSEEE.BTTH....HHHHHHHHHCHHCSTTEEE.SGGGCTT CS
  Amino_oxidase 392 plargsysyvsvgp....ghedydplakpegdprlffAGehtsre 432
                    ++arg  s v+ g+    + +d+ pl      +r+++ G++ +  
     EEA21233.1 274 EWARGPLSCVNDGEvglwQLRDIGPLPTW-TKGRVMLVGDAAHAM 317
                    58899999999998776677777777777.9999***99998855 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (426 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       645  (0.0359752); expected 358.6 (0.02)
Passed bias filter:                      562  (0.0313459); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              16  [number of targets reported over threshold]
# CPU time: 0.63u 0.26s 00:00:00.89 Elapsed: 00:00:00.44
# Mc/sec: 2891.75
//
Query:       EEA21234.1  [L=548]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-15   57.2  25.4    1.3e-15   57.2  25.4    2.7  3  MFS_1     Major Facilitator Superfamily
    1.5e-08   34.0  15.0    1.5e-06   27.3   6.2    3.2  3  Sugar_tr  Sugar (and other) transporter
  ------ inclusion threshold ------
        2.3    8.3   5.9       0.95    9.5   0.3    3.0  2  DUF485    Protein of unknown function, DUF485


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   1.8     0.059   3.5e+02     123     145 ..      75      97 ..      67     107 .. 0.83
   2 !   57.2  25.4   2.1e-19   1.3e-15       9     335 ..      90     480 ..      77     501 .. 0.77
   3 ?    1.3   5.4     0.022   1.3e+02     113     259 ..     474     530 ..     465     546 .. 0.51

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.059
       MFS_1 123 igllsagfslGailgpllgglla 145
                 ig++s+++ lG  l  ++ggll 
  EEA21234.1  75 IGIISVFSTLGLSLVSGFGGLLG 97 
                 89999999999999999999997 PP

  == domain 2  score: 57.2 bits;  conditional E-value: 2.1e-19
       MFS_1   9 alarsilgpalpl..alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlgagalfp 104
                 +   ++lg+ +p+  a+++d++     i  l+t  +l+++++++++++l+  +Grr v+l + +++++g++l++ ass + + l +r++ Gl+ag + +
  EEA21234.1  90 SGFGGLLGFYIPQyvAVGKDYN----DITKLMTYPSLFMGIGNIIGMPLAIGVGRRVVFLGSTVILVIGAALCA-ASSTYeWQLGFRMVIGLAAGQSES 183
                 4445556677776223344555....78889**************************************66666.477777****************** PP

       MFS_1 105 agaaliadwfpkeergrai....gllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee........... 188
                 ++  +  ++f   er+ ai    ++ ++ + + ++++ +++g+++     ++ + + ai+s + ++l +++lpe++ +r+ +s +e +           
  EEA21234.1 184 VVPMVSQEIFFLHERSTAItvqlAIQAILTCVWTLFASPIAGAIT----PQWWYGLGAILSGVQLILTFFFLPETKYDRPLSSYQEGSstedsttenpd 278
                 *******************44445555577777788888888888....55556666666666666666999999999999988888899999**9999 PP

       MFS_1 189 ................................kgtgpaplvp.......awkallkdpvlwillialllfffgfsglltllplylqevlglsglllagl 248
                                                  + g   ++          ++ll ++v+w+lli  l+ ++ +++ +t+  +++   ++++   +++ 
  EEA21234.1 279 gssvkhevpvctsrppldyvnykprtwksdlrLWIGTPDWAAtwnvlkqTGELLLFPNVIWALLINGLTLGANIAIGTTYGSIITAPPYNWP--NSSAS 375
                 999999999999999999988887777777773444444444333333345666666688999999999999999999999999********..77888 PP

       MFS_1 249 llallalvgail.allagrlsdr............lgrrrrlllallllllaalglallavt....ssavllllvlvl..iGfglgfvfpsllalasdl 328
                 +  ++++v+a +  +l+g+ sd               ++ rl+  ++ ++++++  +l +      ++++++++v ++  + f++  +++++ +++ d+
  EEA21234.1 376 YANIGQIVTALIaLPLLGQGSDWlikcmakrngglHEPEVRLIPLIIPVIVGTFTAVLYGQGaahpEKYHWFIYVWAVaaYYFAFVGANIASVTYLLDS 474
                 899999999998899********8888766666665559999999999999999999999889999999999996666336665555577777888887 PP

       MFS_1 329 appeeag 335
                 +p  + g
  EEA21234.1 475 YP-ARVG 480
                 76.5555 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.022
       MFS_1 113 wfpkeergraigllsagfslGa.ilgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeeekgtgpaplvpawkallkdpvlw 210
                  +p  + g ++ ++ a+ ++ +    ++ ++++a s g+ ++f +++++++++++l++                                         
  EEA21234.1 474 SYPA-RVGPMLVIICAFRGILSfGTSYGTAPFIA-SHGYDGAFGAFGALTAVLGLLGI----------------------------------------- 529
                 5554.44444444444333333244455555555.55666666666666666666443......................................... PP

       MFS_1 211 illialllfffgfsglltllplylqevlglsglllaglllallalvgai 259
                                                                 +
  EEA21234.1 530 ------------------------------------------------P 530
                 ................................................3 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   6.2   2.6e-10   1.5e-06      61     130 ..     126     192 ..      89     192 .. 0.91
   2 !   20.2   1.5   3.7e-08   0.00022     373     442 ..     187     256 ..     184     265 .. 0.93
   3 ?   -4.9   5.6       1.6   9.3e+03     347     407 ..     446     503 ..     419     534 .. 0.49

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 2.6e-10
                 HHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTT CS
    Sugar_tr  61 iGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEi 130
                 iG +++++l+  +GR+ ++l ++v++viga+l+aa+    ++e  +  R+++G+++G    +vPm  +Ei
  EEA21234.1 126 IGNIIGMPLAIGVGRRVVFLGSTVILVIGAALCAASS---TYEWQLGFRMVIGLAAGQSESVVPMVSQEI 192
                 89999********************************...89999999*****************99986 PP

  == domain 2  score: 20.2 bits;  conditional E-value: 3.7e-08
                 HHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT CS
    Sugar_tr 373 vlvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkg 442
                 ++++E+f ++ Rs+a+++  a++ + + + +l+   i++ai+  + + + a+l  + +i +fff+petk 
  EEA21234.1 187 MVSQEIFFLHERSTAITVQLAIQAILTCVWTLFASPIAGAITPQWWYGLGAILSGVQLILTFFFLPETKY 256
                 789***************************************99************************95 PP

  == domain 3  score: -4.9 bits;  conditional E-value: 1.6
                 ..CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHH CS
    Sugar_tr 347 aasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfp 407
                 +  +v  v+ + f+++ a  +++v ++l  + +p +v +    i+++   l+      + p
  EEA21234.1 446 WFIYVWAVAAYYFAFVGA-NIASVTYLL--DSYPARVGPMLVIICAFRGILSFGTSYGTAP 503
                 444444444444333333.455555444..5555555555444444443333333333333 PP

>> DUF485  Protein of unknown function, DUF485
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.3   0.00016      0.95      37      82 ..     214     258 ..     200     262 .. 0.88
   2 ?   -1.0   1.0       0.3   1.8e+03      19      32 ..     448     461 ..     442     474 .. 0.65

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00016
      DUF485  37 fapdllatkvgegnitvglllgllqivltflltglYvrrAnrefDp 82 
                    +l+a +++ g+it  +++gl+ i++ + l+  +    ++++D+
  EEA21234.1 214 CVWTLFASPIA-GAITPQWWYGLGAILSGVQLILTFFFLPETKYDR 258
                 455799*****.************************9999999997 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.3
      DUF485  19 pltaiflvvYfgfv 32 
                 + + ++ ++Yf+fv
  EEA21234.1 448 IYVWAVAAYYFAFV 461
                 33445556666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (548 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       470  (0.0262145); expected 358.6 (0.02)
Passed bias filter:                      236  (0.013163); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.26s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 3501.38
//
Query:       EEA21235.1  [L=346]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-08   35.7   0.0    3.1e-08   34.1   0.0    1.7  1  PhyH      Phytanoyl-CoA dioxygenase (PhyH)
    3.3e-06   26.1   0.2      0.034   12.9   0.0    2.4  2  DUF1479   Protein of unknown function (DUF1479)


Domain annotation for each model (and alignments):
>> PhyH  Phytanoyl-CoA dioxygenase (PhyH)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.1   0.0   3.5e-12   3.1e-08       1     211 []      39     268 ..      39     268 .. 0.74

  Alignments for each domain:
  == domain 1  score: 34.1 bits;  conditional E-value: 3.5e-12
                 HHHHSEEEETTSS-HHHHHHHHHHHHHH..........HHHCHTTCCSEEEEECEEESTTCCCEECCCHHCHHHHTTHHHHHHHHHHHHTSCEEEEEEE CS
        PhyH   1 feedGylviegflsaeevealraeieal..........ldralesgdkidfffeekaaadedglleksinkvghflhprkvadlvrailgqdvyvaavl 89 
                 f+++G +vi++++s+e+ + ++++  +           +d+ + + ++  ++f+++   +++ ++     +++   +p  v ++++ ++  ++     l
  EEA21235.1  39 FHKNGCVVIKNVISKEKAKYYCDKQIEWlhkfdlgfdeNDESTWTAEHLPVNFKGGMYYAYAAPH--EKMAWEARIEP-AVIEIFEKLWETKE-----L 129
                 79999999999999988777776544443544555555444444455555555555555555555..33444444444.77777777777776.....4 PP

                 EEEEEE.EEE-TTTCB-E.EEE.E-SGGGSTEESGCCEEEEEEESS-B-TTBT-EEEETTGGGS-CCGTCCHHCSGCCTTS.................. CS
        PhyH  90 qsmyqd.ifkqpkiGgev.qpw.HqDstflptdpeesvvgvwialedateenGclrfiPGSHkweegplrrrlpeddteae.................. 167
                  s +   ++  p+  + + +pw H+D+  ++     ++v+  + + +  ++ G+l ++ GS k   + +    +++++ +e                  
  EEA21235.1 130 ISSFDGlNVSLPRRKDLAgTPWpHCDQNQARK--GMQAVQGLLNFAPNGPKDGGLVLMKGSAKL--FNEYFSQDRESYAHEdapppelkyqdlflfdpk 224
                 56663467777877777775544*******84..59****************************..55455555555555588***************8 PP

                 CCCTTTGHGSCEEEE.BTTTEEEEEETTSEEEE-TB.SSSXEEE CS
        PhyH 168 ddeakkedeeeavpvevkaGdavlfhgrllHgsgaNrsdksRra 211
                 d ++ ++   e v +++++Gd+vl+++r++H ++  + d++R++
  EEA21235.1 225 DLKWFEDRGCELVKINMEPGDFVLWDSRTIHYAELPQGDQIRHV 268
                 8888888899************************9999999985 PP

>> DUF1479  Protein of unknown function (DUF1479)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.9   0.0   3.8e-06     0.034      65     102 ..      33      70 ..       5     132 .. 0.80
   2 !   11.2   0.0   1.2e-05      0.11     323     376 ..     240     292 ..     202     306 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 3.8e-06
                 HHHHHHHHHHTEEEEETSS-HHHHHHHHHHHHHHHHHT CS
     DUF1479  65 aefsaeikrrGvlvvrgvvpeeeaeewkeeikeYlekn 102
                  + ++e+++ G++v+++v+++e+a+ + ++  e+l+k 
  EEA21235.1  33 GDWRDEFHKNGCVVIKNVISKEKAKYYCDKQIEWLHKF 70 
                 567899*******************9988888877765 PP

  == domain 2  score: 11.2 bits;  conditional E-value: 1.2e-05
                 -B-TT-EEEEETT--EEE-SBCSSSS-EEEEE--B-EESHHHHHHHHHHHHHHH CS
     DUF1479 323 dleaGDyvvWhcdlihavdkehegkkdssvlYipavPltqknaeylarqrkafl 376
                 ++e+GD+v+W + +ih  +  ++g++ + v Yi  +P      e l+ ++++f 
  EEA21235.1 240 NMEPGDFVLWDSRTIHYAE-LPQGDQIRHVQYICMTPRRFATKEALELKKQCFN 292
                 699*************865.789**************98777777777777775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (346 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       338  (0.0188521); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.33s 00:00:00.95 Elapsed: 00:00:00.55
# Mc/sec: 1896.47
//
Query:       EEA21236.1  [L=595]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-39  136.5   0.0    1.7e-39  136.1   0.0    1.2  1  PepX_C         X-Pro dipeptidyl-peptidase C-terminal non-cata
    3.7e-39  134.9   0.4    1.4e-36  126.5   0.1    2.2  2  Peptidase_S15  X-Pro dipeptidyl-peptidase (S15 family)
  ------ inclusion threshold ------
      0.094   12.0   0.0       0.15   11.3   0.0    1.3  1  Hydrolase_4    Serine aminopeptidase, S33


Domain annotation for each model (and alignments):
>> PepX_C  X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  136.1   0.0   2.9e-43   1.7e-39       1     225 [.     339     588 ..     339     589 .. 0.92

  Alignments for each domain:
  == domain 1  score: 136.1 bits;  conditional E-value: 2.9e-43
      PepX_C   1 ngvertppvrlqvldggsgs..twrtedawpspntkattlylsqrgagstgdgtlsaasplsdeaaaseedlydptnpldqdqreeradslafttapla 97 
                 ng+e+tp+vr+  l +g++   + +  +++p+pnt++++lyl        +dg l++ +p + +++   +++y++          e+ +s a +++++a
  EEA21236.1 339 NGWEKTPKVRWSALRFGDRAaiDDIILEDFPAPNTEYRKLYLA-------KDGLLKTDAPSNADVE---TVSYNS----------EQRESIAEFSYTFA 417
                 9****************999***********************.......9999988888888888...7*****..........9999********** PP

      PepX_C  98 edtelvGapkakLrvssdapda.dlsvtLvdvdpdGea.............................tlitkGwlrlsnRasdeep............. 153
                 ++t+l+G pka L+vs d++d+ +++v L++ d++G+                               l ++G+lr+s+Ra+d  +             
  EEA21236.1 418 KATQLIGLPKAVLYVSNDKQDDfTVFVILRKRDRNGKLlmhlnfpieatpvksieeisekdqqstnlYLGSTGILRASHRAYDSIKsihpqfpfhphtk 516
                 ********************999************5555555555555666667667778888877777788************999************ PP

      PepX_C 154 .eplePGevydleieLqptayrfpkGhrlrlsvsssdfpmilpnpetdtltldlaklkakntvhtgaerpssl 225
                   ++ PGe+++lei +++++y+f+ G+++ l vs+++  +++ ++ +++++ ++ +  + +t+h g+ +pss+
  EEA21236.1 517 qDKVRPGEIVKLEIGIWAMGYDFEEGETISLQVSGQYPSIAEFKSFSQPRPDHELNR-GLHTIHIGKDYPSSI 588
                 ***************************************************998888.*************97 PP

>> Peptidase_S15  X-Pro dipeptidyl-peptidase (S15 family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  126.5   0.1   2.4e-40   1.4e-36       1     157 [.      62     231 ..      62     243 .. 0.90
   2 !    7.0   0.0   0.00066       3.9     199     257 ..     245     301 ..     230     312 .. 0.85

  Alignments for each domain:
  == domain 1  score: 126.5 bits;  conditional E-value: 2.4e-40
                    TS-EEEEEEEEE..TTSSSEEEEEEEESS-CCT.CCCCHTTCHHCCHGGGHH..................HHHTT-EEEEEE-TTSTTS-S---TT CS
  Peptidase_S15   1 DGvrLavdiyrPetkskeklPvlltrtPYgkndelasdkalaleelelqdkv..................fvarGYavVvqdvrGtggSeGeftvg 78 
                    DG rL +diyrP ++s ek+P++l  + Ygk+ +  + + ++  +      v                  + +rGYa++ +d+rG g+S+G++ v+
     EEA21236.1  62 DGARLYIDIYRP-ANSTEKVPAILSWSFYGKKYSALEMLPMTVWNCC----VpredlsgiekfegldpqtWCPRGYAIISVDTRGAGHSDGQIGVM 152
                    9***********.999**************87755555554443332....145679999************************************ PP

                    TTTHHHHHHHHHHHHHHCTTEEEEEEEEEECHHHHHHHHHCTT--TTEEEEEEECE-S-TCCCCSECTTEEBCCHHHHH CS
  Peptidase_S15  79 dsdeaedgadvidWlakqpwsnGkVgmtGiSYlGttqllaaatgvpalkaivpeaaisdlyddyyregGlvrapgglsw 157
                    ++++aedg+dv++ +ak +w+nG++gm G+S l++ q+ +a++++p lkai+p  +  d y++ +++gG +   +++  
     EEA21236.1 153 GTQDAEDGYDVVEAVAKMDWCNGHIGMAGNSALAISQWFIASQQPPSLKAIAPWEGSGDIYREQFCRGGWFFMSNFDLI 231
                    *********************************************************************9998888765 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.00066
                    THHHHCCCC--SSSHHHHTT-HHHHHCT--S-EEEEEECCSSTTCCHHHHHHHHHCCTT CS
  Peptidase_S15 199 tpveselletgdydafWkdrnlsedadkvkapvllvgGwnDwnvkngaiklyealkapg 257
                    + +e+++ +++  +afW+d++++  ++k+++pv++ g+    +++ g+++++ +l+  +
     EEA21236.1 245 EDFEEMYRRSNLSNAFWEDKRAD--MTKIQCPVYIRGSDVSSIHTMGSVRAWLELPHDN 301
                    4589999999***********88..7*********999999888899999998888765 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   2.5e-05      0.15      27      84 ..     127     183 ..     124     204 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 2.5e-05
  Hydrolase_4  27 LaaqGfavyalDhrGhGrsegkrghvpsfddyvdDlaafvekvk.eehpelplfllGhS 84 
                  +  +G+a++ +D rG G+s+g+ g v  ++d  d  +  ve+v+  ++ +  + + G S
   EEA21236.1 127 WCPRGYAIISVDTRGAGHSDGQIG-VMGTQDAEDGYDV-VEAVAkMDWCNGHIGMAGNS 183
                  6679*****************999.6666665443333.33333255555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (595 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       342  (0.0190752); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 3906.98
//
Query:       EEA21237.1  [L=1659]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      9e-11   41.9   0.0    1.6e-10   41.1   0.0    1.3  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
      2e-07   31.2   0.1    5.5e-06   26.6   0.0    2.6  2  rve              Integrase core domain
    0.00021   21.0   0.2    0.00072   19.4   0.2    1.8  1  gag_pre-integrs  GAG-pre-integrase domain
  ------ inclusion threshold ------
       0.16   12.2   0.0       0.75   10.0   0.0    2.1  2  PAC4             Proteasome assembly chaperone 4
       0.87    9.7   8.7       0.45   10.7   0.1    3.5  3  Integrase_H2C2   Integrase zinc binding domain


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.1   0.0   4.4e-14   1.6e-10       7     178 ..    1150    1325 ..    1146    1382 .. 0.81

  Alignments for each domain:
  == domain 1  score: 41.1 bits;  conditional E-value: 4.4e-14
       RVT_2    7 slPkdrkaigsrWvftkkkddlkevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeee.lvvhqldvdsafLnae..ldeevyvkqP 100 
                  + P + +  g r+v   k++  +++  k+rlv+q ++ k ++++  + +P i+ +s rL+l + + ++ +  +  dv  a+++++  l+ e y++ P
  EEA21237.1 1150 DIPLEARIYGFRFVDEVKNKGTDKAFEKSRLVVQAYNDK-DKEFVLTQSPTIQRSSQRLILCIGTSKDgVRFWIRDVTQAYIQSTtkLNREFYIRIP 1245
                  568889999*********9999**************987.567999*****************876651556677*******987336788****** PP

       RVT_2  101 pGfeidreeekvykLnkslyGlkqapllWnekidk.vLkklgferseaesGly.vrgtgegklivalyvddlliagsdik 178 
                  p         +  ++ + lyG+  a+  W+++ ++   ++lg+e s+    l  +    +g  ++++  dd li++++  
  EEA21237.1 1246 PELRHYFPGCEFLRVVRPLYGIPEAGNHWFRTYHEhHTTHLGMETSTYDPCLLhCCDPKQGFGVIGMQTDDTLIVADEAF 1325
                  ****99888999*****************99886615678899999998876515555666689**********998764 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.0      0.09   3.2e+02      30      91 ..     699     766 ..     695     771 .. 0.76
   2 !   26.6   0.0   1.5e-09   5.5e-06       7     117 ..     788     891 ..     783     893 .. 0.78

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.09
         rve  30 vddfsrlilaealsdemdastvlalleravarfggve.......pervlsDngseytskafrefladlg 91 
                 + d+s + ++ +  de++  +++  l+r  +rfg+          +r  +D  +e++ +++ +f+++ +
  EEA21237.1 699 IWDYSLMSYITQSFDEDQCFLTATELRRLHRRFGHPSvgrlhktLLRAGYDTNPEMI-EKINRFCHHCQ 766
                 679999**********55555555555555566655599999888889999999999.88888888865 PP

  == domain 2  score: 26.6 bits;  conditional E-value: 1.5e-09
         rve   7 lwqvDvtvvripdgggkayllvvvddfsrlilaealsdem..dastvlalleravarfggvepervlsDngseytskafrefladlgirvsftrpgrpq 103
                  + vD+++++    g  + +l++vd ++r+  a+ l + +  ++ ++l++l+  ++ + g  p+ +++D g+ ++sk+f+ ++++lg+     ++   +
  EEA21237.1 788 SIIVDIMYIN----G--KPVLHIVDEATRFNAACWLISISarATWDALRMLW--IDTYLGP-PDFIVTDAGKNFVSKEFTHLASSLGTITVSVPVEAHW 877
                 5667888888....3..5688999**99997666555552004444444444..6666666.**************************999999999** PP

         rve 104 dnGkvErfhrtlkd 117
                 + G vEr h  l++
  EEA21237.1 878 SIGAVERYHAVLRR 891
                 *********99987 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.2     2e-07   0.00072      22      63 ..     722     766 ..     706     767 .. 0.76

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 2e-07
  gag_pre-integrs  22 ssinlWHrRLGHpsfsrlkkLfkkgllpglki..sk.sevCeaCq 63 
                      +++++ HrR+GHps++rl+k   +   + +++  +k +++C++Cq
       EEA21237.1 722 TELRRLHRRFGHPSVGRLHKTLLRAGYDTNPEmiEKiNRFCHHCQ 766
                      678899************9988544444444333555889****9 PP

>> PAC4  Proteasome assembly chaperone 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0       4.5   1.6e+04      27      42 ..     345     360 ..     327     372 .. 0.66
   2 ?   10.0   0.0   0.00021      0.75      32      70 ..     485     525 ..     465     528 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 4.5
        PAC4  27 plgslvvAmpsrtnkk 42 
                 +l++l +++p+  + +
  EEA21237.1 345 KLQDLFYCLPDELQTQ 360
                 5799999999988733 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00021
        PAC4  32 vvAmpsrtnkktptisTtLlgdg.sde..aserlAqrLArRl 70 
                  +++p+rt+ + pt++T  ++   +d   +s++lA+ LA R 
  EEA21237.1 485 QYSLPDRTK-NEPTTATGYFTVAaTDHneFSSSLASELANRS 525
                 699*****9.7799999999777553355**********995 PP

>> Integrase_H2C2  Integrase zinc binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.1     0.099   3.5e+02      25      42 ..     274     291 ..     272     293 .. 0.86
   2 ?   10.7   0.1   0.00013      0.45      10      53 ..     724     769 ..     719     772 .. 0.89
   3 ?   -0.1   1.0      0.28     1e+03      10      23 ..    1275    1289 ..    1269    1293 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.099
  Integrase_H2C2  25 tlerlrrryyWpgmrkdv 42 
                     +l+ ++  yyW ++++ +
      EEA21237.1 274 MLKDVALSYYWDNIDQWI 291
                     7889999*******9977 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 0.00013
  Integrase_H2C2  10 lkeaHdsagHlGiektlerlrrryy..WpgmrkdvkkyvksCetCq 53 
                     l+++H   gH+++ +  ++l r  y   p m +++++++++C+t  
      EEA21237.1 724 LRRLHRRFGHPSVGRLHKTLLRAGYdtNPEMIEKINRFCHHCQTYG 769
                     899****************99999866799************9875 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.28
  Integrase_H2C2   10 lkeaHds.agHlGie 23  
                      ++ +H++ + HlG+e
      EEA21237.1 1275 FRTYHEHhTTHLGME 1289
                      799**********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1659 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       614  (0.0342462); expected 358.6 (0.02)
Passed bias filter:                      492  (0.0274416); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 1.00u 0.31s 00:00:01.31 Elapsed: 00:00:00.50
# Mc/sec: 9915.56
//
Query:       EEA21238.1  [L=499]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-44  152.9  41.8    5.6e-44  150.5  41.8    2.1  1  MFS_1     Major Facilitator Superfamily
    5.4e-20   71.4  13.5      6e-20   71.2  11.7    1.7  2  TRI12     Fungal trichothecene efflux pump (TRI12)
      1e-12   47.7  10.8      1e-12   47.7  10.8    2.4  2  Sugar_tr  Sugar (and other) transporter
  ------ inclusion threshold ------
       0.35    9.2  14.7      0.013   13.9   2.7    2.2  2  MFS_3     Transmembrane secretion effector


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  150.5  41.8   1.3e-47   5.6e-44      13     352 ..      30     422 ..      21     423 .. 0.85

  Alignments for each domain:
  == domain 1  score: 150.5 bits;  conditional E-value: 1.3e-47
       MFS_1  13 silgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlgagalfpagaali 110
                 +++++alp ++a +l+++ se++++ ++y+l++ +++++++r+sd +Gr+ +l+++ ++f++g+l++++ s ++ +++ +rv qGlg+g++  ++ ++i
  EEA21238.1  30 TVVATALP-TIAAHLNATTSEYSWVGSAYTLASTASTPLWARVSDICGRKEILMVTNVTFLVGSLICAL-SISPgMMIGGRVAQGLGGGGISVVVTIVI 126
                 67889999.******************************************************888887.45566************************ PP

       MFS_1 111 adwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee..................... 188
                  d+fp +er+++++l ++ +++++ +gpllgg++++ +gWr++fyi+ ++  l+  l++l+l  + p++k k +++ +                     
  EEA21238.1 127 GDLFPLRERAKYYALTGIVWAISSGVGPLLGGVFTQTIGWRWCFYINLPFDGLS--LAFLFLALKLPAKKQKQSWQSLlysfdwlgsilivggticfly 223
                 ******************************************************..6669999999999999999999********************* PP

       MFS_1 189 ...................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllal 252
                                                       ++ p+vp ++ l+ +  l ++l ++++ +f+f ++ ++ ply+q+vlg +  +++gl+  +
  EEA21238.1 224 glevgaskqhpwgsaytlgllitgiviltifglyeTFYANNPIVP-IRVLKDRSIL-ACLSTAFCHSFIFIAYDYFNPLYFQTVLGVT-PIQSGLYTLA 319
                 ****99999999998888888877777777776654445555666.7777777755.599999999999999****************.5666666666 PP

       MFS_1 253 lalvgailallagrlsdrlgr.rrrlllallllllaalglallavtssavllll.vlvliGfglgfv.fpsllalasdla.ppeeagtasglfntagsl 347
                 l l   ++ l +g++++r+g+ r+ +++++++++l++ +++ ++++   v+ ++   +++G+g+g   +++++a+ s+l+  ++  ++a+++f+++++l
  EEA21238.1 320 LVLPLSAMTLTSGFIVKRTGAyRPVIWVGGSIMVLGTGLFIDFGPS-RVVAKIVvYQIIAGLGAGPLfQAPMIAFQSQLIrKEDLLAAAIAAFTFLRNL 417
                 66666666779**********5666666666666666666666666.777777735566888666663555555555555577999************* PP

       MFS_1 348 ggalg 352
                 ++al+
  EEA21238.1 418 STALS 422
                 *9986 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.2  11.7   1.3e-23     6e-20      62     315 ..      31     281 ..      24     289 .. 0.87
   2 ?    0.1   0.0     0.046     2e+02     516     551 ..     277     315 ..     275     320 .. 0.77

  Alignments for each domain:
  == domain 1  score: 71.2 bits;  conditional E-value: 1.3e-23
       TRI12  62 asasalpnilqdvgqs.ensslfstlwttgqavsilvmgrltdrfgrrpfvilthilglvgaivgctatkfntllaamtllgvaagpag.asplfvgel 158
                   a+alp i   +  +  + s + + +t+  + s  +  r++d  gr+ ++++t +  lvg+++ + +     ++      g+  g       +++g+l
  EEA21238.1  31 VVATALPTIAAHLNATtSEYSWVGSAYTLASTASTPLWARVSDICGRKEILMVTNVTFLVGSLICALSISPGMMIGGRVAQGLGGGGISvVVTIVIGDL 129
                 568999*99998865414457778899*************************************9999999999999999999877654156899**** PP

       TRI12 159 ms..nktkflgllivsipvvvtsglspylgqrlaiqgswrwifyiyiitsaiavllivvwyyppsfaqlhgkkvrkreelakldwigiilvivgvslfl 255
                 +   +++k+  l    i   + sg++p lg  ++    wrw fyi +    +++ ++ +    p+ +q    k + +  l   dw+g il++ g+  fl
  EEA21238.1 130 FPlrERAKYYAL--TGIVWAISSGVGPLLGGVFTQTIGWRWCFYINLPFDGLSLAFLFLALKLPAKKQ----KQSWQSLLYSFDWLGSILIVGGTICFL 222
                 761156666665..4566677899*******************************9999999998776....67788899******************* PP

       TRI12 256 lgvswggkpnspwnsakviglissglgslvvfalyevygkpvrpivppalfkdtrgfvci 315
                  g+  g   + pw sa  +gl+ +g+  l +f lye +   ++pivp  ++kd   + c+
  EEA21238.1 223 YGLEVGASKQHPWGSAYTLGLLITGIVILTIFGLYETFY-ANNPIVPIRVLKDRSILACL 281
                 *************************************96.579**********9888886 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.046
       TRI12 516 iaavvsramadsyt...asyanvyyfamalgvipiiasl 551
                 i a +s a++ s+      y n  yf   lgv pi + l
  EEA21238.1 277 ILACLSTAFCHSFIfiaYDYFNPLYFQTVLGVTPIQSGL 315
                 667788888888742214799*************98766 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.7  10.8   2.3e-16     1e-12      42     190 ..      44     186 ..      17     201 .. 0.92
   2 ?   -1.2   5.0      0.15   6.9e+02      45     117 ..     310     383 ..     248     391 .. 0.77

  Alignments for each domain:
  == domain 1  score: 47.7 bits;  conditional E-value: 2.3e-16
                 HH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHH CS
    Sugar_tr  42 eessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalv 140
                 +++++ ++++ s++ + ++++  +   ++d+ GRk +l++++v f++g++++a++    s  ++i gRv  G+g G++sv+v++ i+ + p + R +  
  EEA21238.1  44 NATTSEYSWVGSAYTLASTASTPLWARVSDICGRKEILMVTNVTFLVGSLICALSI---SPGMMIGGRVAQGLGGGGISVVVTIVIGDLFPLRERAKYY 139
                 34788999************************************************...**************************************** PP

                 HHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGG CS
    Sugar_tr 141 slyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllf 190
                  l+   +++   v+  +g ++ +t +   wr+ ++++l +  l l++l++
  EEA21238.1 140 ALTGIVWAISSGVGPLLGGVFTQTIG---WRWCFYINLPFDGLSLAFLFL 186
                 *****************999999888...********9999888887765 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.15
                 ..HHHHHHHTHHHHHHHHHHHHHHHHHHTT.HHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHH CS
    Sugar_tr  45 svlsglivsiflvGaiiGslfagllgdrfG.RkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvG 117
                  ++sgl + ++++   +  l++g++++r G +++++ +++ ++v g+ l +     + v  ++v ++++G+g+G
  EEA21238.1 310 PIQSGLYTLALVLPLSAMTLTSGFIVKRTGaYRPVIWVGGSIMVLGTGLFIDFGPSRVVAKIVVYQIIAGLGAG 383
                 56777777777777777788899999999877889999999999998887766666788888888999999988 PP

>> MFS_3  Transmembrane secretion effector
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   2.7     3e-06     0.013      68     176 ..      71     174 ..      30     204 .. 0.82
   2 ?    0.8   4.3     0.027   1.2e+02      45     163 ..     311     430 ..     301     435 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 3e-06
       MFS_3  68 laDnfdrRkvllavqlllalvsvlltvlaalgllspwlllaltlligiGaalndPaWqAsvgelvkrrdvpaAvaLnsvginiaRsvGPAlgGvlvaav 166
                 ++D+  r+++l+++ +  +++s++ +++     +sp ++++  +  g+G    +     ++g+l + r+  +  aL+ + + i+  vGP lgGv   ++
  EEA21238.1  71 VSDICGRKEILMVTNVTFLVGSLICALS-----ISPGMMIGGRVAQGLGGGGISVVVTIVIGDLFPLRERAKYYALTGIVWAISSGVGPLLGGVFTQTI 164
                 7899999999999999999999877665.....689999************9999******************************************** PP

       MFS_3 167 Gaalafavna 176
                 G  + f +n 
  EEA21238.1 165 GWRWCFYINL 174
                 ******9873 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.027
       MFS_3  45 lmvAlvqaaatLPifllsilaGalaDnfd.rRkvllavqlllalvsvlltvlaalgllspwlllaltlligiGaalndPaWqAsvgelvkrrdv.paAv 141
                 ++  l   a  LP+  +++ +G +       R v+ ++ ++++l++ l + +    +++ +++  ++  +g G  +++P   A  ++l++++d+  aA+
  EEA21238.1 311 IQSGLYTLALVLPLSAMTLTSGFIVKRTGaYRPVIWVGGSIMVLGTGLFIDFGPSRVVAKIVVYQIIAGLGAGPLFQAPM-IAFQSQLIRKEDLlAAAI 408
                 55556666777888889999998887765156666677777777777777777777666655555555555555566664.577788888888625678 PP

       MFS_3 142 aLnsvginiaRsvGPAlgGvlv 163
                 a  +   n++ +    +gGv++
  EEA21238.1 409 AAFTFLRNLSTALSLVVGGVIL 430
                 8888889999999999999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (499 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       616  (0.0343577); expected 358.6 (0.02)
Passed bias filter:                      329  (0.0183502); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.66u 0.31s 00:00:00.97 Elapsed: 00:00:00.51
# Mc/sec: 2960.20
//
Query:       EEA21239.1  [L=471]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-32  113.3  29.6    3.8e-20   72.1   6.5    2.0  2  AA_permease_2  Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.8  18.5   4.2e-16   7.6e-12      58     211 ..      96     257 ..      92     271 .. 0.85
   2 !   72.1   6.5   2.1e-24   3.8e-20     234     403 ..     260     458 ..     256     468 .. 0.77

  Alignments for each domain:
  == domain 1  score: 44.8 bits;  conditional E-value: 4.2e-16
  AA_permease_2  58 lprsgGiyvytkaaf....gkkvaflsawfnwfayvpvlasilsvaasyl..lnalgpdlqg.ntwltyliaiaililvalinirgikesakiqni 146
                     p+sgG+y++++ +     +k++ f+++w++++++ ++la+++ + ++++  l +lg +l++  +w+  li++a l l  ++n++g k + +iq++
     EEA21239.1  96 APTSGGQYHWAAMLApvkcQKVLSFVTGWLAVIGWQAALAASSFMTGQMIrsLAILGNQLYNaLPWQDTLIIWATLSLSLTVNLIGGKLLPRIQVV 191
                    49************6555589999**************************76666775554416******************************** PP

  AA_permease_2 147 lgilkillpliiliilglitvdgggfsslstetdtffpn..gwpgv...llgllivlwsfdGfesaanvs 211
                    + +l+il++++i+i + ++++ ++++ +     +tf+++  ++++    ++g++++++ f+G +++++v+
     EEA21239.1 192 VLVLHILGFFAIMI-TLVYMAEPNTAKEV---FTTFQNGggFSTQAlswFVGMTGSAFGFAGGDGVVHVA 257
                    *******9999999.8888889****953...44555445466664556999999*************97 PP

  == domain 2  score: 72.1 bits;  conditional E-value: 2.1e-24
  AA_permease_2 234 yllvniaflgvvpddeianlsn..lgsvaalffeavggkvvaiivvilialsllgaintavigssrvlealardgvlP..rffakvn.kfgspira 324
                     +++ +a+l++  +d   +l++    +++++f+ea+++  ++i++ +++++    a++++++g+sr+l++++rd++ P  r++++v+  ++ p++a
     EEA21239.1 260 AFGMIVAMLFCAEPDHGGELREitGYDFMGIFMEATNSLSGTIAMCLIVIIFYGCAVMGLLTGASRQLWSFSRDRGVPgwRWWKQVStTRHLPVNA 355
                    5666777777777766655555212457********95566666666666666669*******************************9******** PP

  AA_permease_2 325 iiltaivslillllfllassaaynfllsvsslgliisyllliigalilrkkrphlkr..........pgk...............ilvaiigalfl 395
                    i +++++s++l+l+ ++ s+ a++ ++s+++ g+++syl++++++li r++  +++           pg+               + +  +ga ++
     EEA21239.1 356 ILFSVTISTLLGLIKIG-STLAMYDVVSLAVSGIYLSYLVVATLLLIRRVQGYIYQSsdsedelvnvPGAnfwpslmnptveeinWAILRVGATMF 450
                    *********99977766.6899*****************************999955556677888844455557888888885544444445555 PP

  AA_permease_2 396 lfllvalf 403
                    l+++++ f
     EEA21239.1 451 LIMIYFVF 458
                    55555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (471 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       696  (0.0388198); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 3012.44
//
Query:       EEA21240.1  [L=189]
Description: acetyltransferase, GNAT family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.4e-08   33.4   0.0    5.7e-08   33.0   0.0    1.4  1  Acetyltransf_1   Acetyltransferase (GNAT) family
    1.3e-07   31.6   0.0    3.2e-07   30.3   0.0    1.6  2  Acetyltransf_10  Acetyltransferase (GNAT) domain
    5.3e-07   30.0   0.0    8.1e-07   29.4   0.0    1.3  1  Acetyltransf_7   Acetyltransferase (GNAT) domain
     0.0028   17.7   0.3       0.34   11.0   0.0    3.0  3  Acetyltransf_9   Acetyltransferase (GNAT) domain
  ------ inclusion threshold ------
      0.018   15.2   0.2       0.11   12.7   0.0    2.0  2  TPR_9            Tetratricopeptide repeat
       0.24   11.1   0.0       0.31   10.7   0.0    1.2  1  MOZ_SAS          MOZ/SAS family


Domain annotation for each model (and alignments):
>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.0   0.0   1.9e-11   5.7e-08      49     117 .]     107     169 ..       9     169 .. 0.71

  Alignments for each domain:
  == domain 1  score: 33.0 bits;  conditional E-value: 1.9e-11
                     EEEEEETTSTTEEEEEEEEESGGGTTSSHHHHHHHHHHHHHHHTTESEEEEEEETTEHHHHHHHHHTTE CS
  Acetyltransf_1  49 sllkipdekggvayieslaVspeyrgkGlGsaLlealeerareegikkivlaveedndaairlYeklGF 117
                     +++   d  ++++y++ +  +p+y+++G+Gs+L++   + a +  + + ++   +  +   ++Y+k+GF
      EEA21240.1 107 RMRVMGD--EKHYYLDTVGTHPNYQRRGAGSMLVQWGCDLADRDDVSA-YV---DASKEGAPVYQKHGF 169
                     4444444..8*****************************999997755.55...3356778*******9 PP

>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0      0.49   1.5e+03       7      31 ..      93     117 ..      89     122 .. 0.75
   2 !   30.3   0.0   1.1e-10   3.2e-07      53     109 ..     118     172 ..     107     178 .. 0.84

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.49
  Acetyltransf_10   7 eegietfkefispealrerieegea 31 
                       e +e+f +++++e++r + +e+++
       EEA21240.1  93 YERCEEFIDILEKERMRVMGDEKHY 117
                      6788999999999999987654444 PP

  == domain 2  score: 30.3 bits;  conditional E-value: 1.1e-10
  Acetyltransf_10  53 hisllfVdpeyrgqGigkaLleaveeeaekdgikleltvnaspyavpfYeklGFkav 109
                      ++  +  +p+y+++G g++L++  ++ a++d+   +  v+as++  p+Y+k+GF++ 
       EEA21240.1 118 YLDTVGTHPNYQRRGAGSMLVQWGCDLADRDDV--SAYVDASKEGAPVYQKHGFVDY 172
                      5666778*********************88865..69*****************986 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.4   0.0   2.7e-10   8.1e-07      25      75 ..     117     170 ..      95     171 .. 0.68

  Alignments for each domain:
  == domain 1  score: 29.4 bits;  conditional E-value: 2.7e-10
                     TCTEEEEE-GGGTTSSHHHHHHHHTTSEEE....EE.EEEETHH.HHHHHHHHTTEE CS
  Acetyltransf_7  25 aeitrlaVdpeyrgkGiGraLleaaekgii....le.qlelnae.kaikfYeklGFe 75 
                     +++  + ++p+y+++G G+ L++    g+         ++++a+ + ++ Y+k+GF+
      EEA21240.1 117 YYLDTVGTHPNYQRRGAGSMLVQW---GCDladrDDvSAYVDASkEGAPVYQKHGFV 170
                     4555599****************8...5542232122344433247789*******8 PP

>> Acetyltransf_9  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.0     0.057   1.7e+02       4      24 ..      14      34 ..      12      43 .. 0.89
   2 ?    0.7   0.0      0.18   5.2e+02      10      28 ..      46      64 ..      41      79 .. 0.85
   3 !   11.0   0.0   0.00011      0.34      75     125 ..     118     169 ..      90     170 .. 0.78

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.057
                    EE-GGGHHHHHHHHHHHTT-- CS
  Acetyltransf_9  4 elteedldevlellkyaFqde 24
                    e+t ed++++ +++ +aF + 
      EEA21240.1 14 EATIEDFPAIRDIWFAAFTQP 34
                    7999**************875 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.18
                    HHHHHHHHHHHTT----H. CS
  Acetyltransf_9 10 ldevlellkyaFqdeespl 28
                    ++++l+++++aF de+s+ 
      EEA21240.1 46 FQKYLRVVDTAFRDEQSRP 64
                    7899**********99875 PP

  == domain 3  score: 11.0 bits;  conditional E-value: 0.00011
                     EEEEEEE-CCGTTS-HHHHHHHHHHHHHHHTT--EEEE--SS.HHHHHTTT- CS
  Acetyltransf_9  75 gvtgVavapehrgrgvlskLlaraleemreegqplsllfPss.ipiYrrfGy 125
                     ++  V+++p++++rg  s L++   + ++ ++++  +    + +p+Y++ G+
      EEA21240.1 118 YLDTVGTHPNYQRRGAGSMLVQWGCDLADRDDVSAYVDASKEgAPVYQKHGF 169
                     6778***********9888887777666665655555555444588888887 PP

>> TPR_9  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0      0.37   1.1e+03      23      33 ..      86      96 ..      83      98 .. 0.87
   2 ?   12.7   0.0   3.6e-05      0.11      27      61 ..     125     159 ..     121     165 .. 0.87

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.37
       TPR_9 23 llaPddpeerr 33
                +++P +p+er 
  EEA21240.1 86 QWHPSSPYERC 96
                79*******96 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 3.6e-05
       TPR_9  27 ddpeerrdRGlllaqlGclsaAladLeaylalapd 61 
                 ++ + rr  G +l+q+Gc  a ++d  ay++ + +
  EEA21240.1 125 HPNYQRRGAGSMLVQWGCDLADRDDVSAYVDASKE 159
                 56689*************************88765 PP

>> MOZ_SAS  MOZ/SAS family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0    0.0001      0.31      75     110 ..     114     149 ..      94     171 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.0001
     MOZ_SAS  75 aeeynlaCilvlPpyqrkgyGklliefsYeLskrek 110
                 +++y l  + + P+yqr+g G++l++    L+ r+ 
  EEA21240.1 114 EKHYYLDTVGTHPNYQRRGAGSMLVQWGCDLADRDD 149
                 56788889999***************9999988776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (189 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       306  (0.0170673); expected 358.6 (0.02)
Passed bias filter:                      295  (0.0164538); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 1345.49
//
Query:       EEA21241.1  [L=294]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (294 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       807  (0.0450109); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 2142.70
//
Query:       EEA21242.1  [L=795]
Description: polygalacturonase A precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   2.4e-100  335.8  17.3   2.4e-100  335.8  17.3    1.8  2  Glyco_hydro_28  Glycosyl hydrolases family 28
      2e-41  141.6   0.4      2e-41  141.6   0.4    3.0  3  Pectinesterase  Pectinesterase


Domain annotation for each model (and alignments):
>> Glyco_hydro_28  Glycosyl hydrolases family 28
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.1      0.56     5e+03      86     113 ..     133     159 ..     103     163 .. 0.47
   2 !  335.8  17.3  2.7e-104  2.4e-100       1     322 [.     463     790 ..     463     792 .. 0.99

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 0.56
  Glyco_hydro_28  86 kegkkkpkflvikkvknskiknlnikns 113
                     + + +    l++++  n+k++nln+ n+
      EEA21242.1 133 TTNDDLTATLRLWN-PNTKVYNLNVVNT 159
                     33333333333333.2667777777775 PP

  == domain 2  score: 335.8 bits;  conditional E-value: 2.7e-104
  Glyco_hydro_28   1 CssivlsqlevpksgelldllklkgplksgttvtlegtttakvkekngkddivisgekitvlgisGkgtidGqGqawwdgkgkkkkegkkkpkfl 95 
                     C++ivls++++p+ g  +dl++l+    +gttvt++g+tt++ ++++ ++ ++isg+ it++   G + idG+Gqa+wdg g+ + +  k ++f+
      EEA21242.1 463 CTNIVLSNIAAPN-GSAIDLSGLQ----AGTTVTFDGSTTFGFTNSSSFNPMIISGVGITITANPG-AIIDGNGQAYWDGLGS-NGGVPKPDHFI 550
                     *************.**********....**************************************.***************8.8899999**** PP

  Glyco_hydro_28  96 vikkvk.nskiknlniknspvfhfsvesgkdltisditidasagd............hNtDgidvgsskgvtisntnikngDDciainsgsknis 177
                     v+k v+ ns +knl i+n+p++ fs++s++d++++d+++++ ag+            hN+Dg+d++ss+++ ++ t ++n+DDc+ai+sg  n++
      EEA21242.1 551 VVKRVTaNSVVKNLYIQNWPTHLFSISSSSDVVFQDLVLNNTAGNapnalssglaaaHNSDGFDLSSSNNIVVERTLVYNQDDCVAITSGD-NVT 644
                     ****9989***********************************************************************************.*** PP

  Glyco_hydro_28 178 itnvtcggGHGlSiGSvggrsdntVknvtvkdskvknsenGvRIKtikgatgtvsnvkyeniklknva.ypividqdYenkeptgkptsgvkisd 271
                     ++nv+c gGHGlSiGSvgg+s+n+V+n+ + ds v+ns+nG+RIKt++++tg ++n++y+ni++++v+ y++ ++qdY+n++ptg+pt+gv i+d
      EEA21242.1 645 VSNVECHGGHGLSIGSVGGKSNNNVTNIRFADSSVINSQNGCRIKTNYNTTGYIANITYSNIVIRDVSiYGVDVQQDYLNGGPTGTPTNGVFIED 739
                     *********************************************************************************************** PP

  Glyco_hydro_28 272 vtfknvtgtvks.aeavkllcekgskcsdvtmsdvkitggkstskcknvksk 322
                     v f+nvtgt +s a++ ++lc++gs cs++t+ dv+itgg+ +s+c++ ks+
      EEA21242.1 740 VLFQNVTGTATSsAQDYYVLCGDGS-CSNFTFTDVAITGGSRSSSCNYPKSG 790
                     **********999************.*********************99886 PP

>> Pectinesterase  Pectinesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  141.6   0.4   2.3e-45     2e-41       9     270 ..      62     326 ..      52     341 .. 0.87
   2 !    2.2   0.8    0.0068        61      68     109 ..     364     405 ..     356     419 .. 0.82
   3 ?   -1.8   0.0      0.11     1e+03      85     103 ..     578     596 ..     554     611 .. 0.72

  Alignments for each domain:
  == domain 1  score: 141.6 bits;  conditional E-value: 2.3e-45
                     -SSBSSHHHHHHHS-SS-SS-EEEEE-SEEEE--EEE-TTS-SEEEEES.....-TTTEEEEE..---TTTT--SGGG-SEEE-STT-EEES-EE CS
  Pectinesterase   9 sgkfktiseavaavpeksekrfviyvkaGvYeenvevekkktnvvlvGd.....Gkektvitg..sknvvdgkttfktatvavvgegfiarditf 96 
                      g+f+t+++ v+a++++ ++   +++  G+Y+e+v ++k k+n+++ G      G e+ ++t   +++ +++++   tat+     +  + ++ +
      EEA21242.1  62 PGSFSTVQAGVNALNSTATRPQSLFIFPGTYREQVYIPKLKSNLTVQGHthnskGYEQNTVTItyNLALINTTNDDLTATLRLWNPNTKVYNLNV 156
                     589********************************************963333355555555412666677777778****************** PP

                     EE---..GGG----SEEE--TTEEEES-EEE-STT-EEE-SSEEEEES-EEEESSS-EEE--E.EEEES-EEEE---STT--EEEEEE----TTS CS
  Pectinesterase  97 entaG..pekhqavalrvdsDlsvfyrcslegyqDtlyvhskRqfyreceitGtvDfifGnaa.avlqnceivarkplkgqkntvtaqgrkdpnq 188
                      nt G  p++ q  a+  ++    +y c+l gyqDtl + +  q y ++ i+G+vDfifG+aa a + n +i +       + +vta gr+  ++
      EEA21242.1 157 VNTFGhiPKNGQNLAVSAEATGQGYYGCQLIGYQDTLLAETGLQLYAKSLIVGAVDFIFGQAAlAWFENIDIRTIA-----AGSVTASGRSSATN 246
                     *****88899**************************************************9874678888887655.....458*********** PP

                     --EEEEES-EEEE-TTTGGGTTTS-EEEE--SSTT-EEEEES-EE-TTB-TT-S--SSTTT.TTTT-EEEEES-BSTT---TT CS
  Pectinesterase 189 ntGiviqnckitaeedllavkkkvktyLGRPWkeysrtvimeskiedvidpeGwleWngdf.alktlyYgeyknsGpgaetsk 270
                      +  vi++++++a +++        +yLGRPW +++r+v+ e++++++i p Gw++W++++ ++  +  +e++n Gpg+++++
      EEA21242.1 247 PSWYVINRSNVSAINNTI---PAGVNYLGRPWGSFARVVFQETYLGNIIAPPGWSQWSTSTpNIGNVTLAEFNNYGPGSALQQ 326
                     ************988877...45679*******************************99553899*************98765 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.0068
                     --TTTT--SGGG-SEEE-STT-EEES-EEEE---GGG----S CS
  Pectinesterase  68 knvvdgkttfktatvavvgegfiarditfentaGpekhqava 109
                     ++v++g +t++t+t+ ++g+ f   +i+++ ++ p++    a
      EEA21242.1 364 NDVTTGASTWTTTTIPTSGSTFASSSISISSSSAPSTISTAA 405
                     5678899**********************9999988755544 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 0.11
                     -STT-EEES-EEEE---GG CS
  Pectinesterase  85 vgegfiarditfentaGpe 103
                     +++ ++ +d+ ++ntaG +
      EEA21242.1 578 SSSDVVFQDLVLNNTAGNA 596
                     34578999********976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (795 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       693  (0.0386525); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.26s 00:00:00.87 Elapsed: 00:00:00.40
# Mc/sec: 6019.36
//
Query:       EEA21243.1  [L=193]
Description: hypothetical protein PMAA_050610 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (193 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       355  (0.0198003); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.39
# Mc/sec: 1471.80
//
Query:       EEA21244.1  [L=303]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.8e-22   80.7   0.0    2.2e-22   80.3   0.0    1.1  1  PhyH            Phytanoyl-CoA dioxygenase (PhyH)
  ------ inclusion threshold ------
      0.014   16.2   0.1      0.024   15.5   0.1    1.3  1  2OG-FeII_Oxy_3  2OG-Fe(II) oxygenase superfamily
      0.015   15.7   0.1      0.026   14.9   0.1    1.5  1  2OG-FeII_Oxy_5  Putative 2OG-Fe(II) oxygenase


Domain annotation for each model (and alignments):
>> PhyH  Phytanoyl-CoA dioxygenase (PhyH)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.3   0.0   3.8e-26   2.2e-22       2     210 ..      41     227 ..      40     228 .. 0.82

  Alignments for each domain:
  == domain 1  score: 80.3 bits;  conditional E-value: 3.8e-26
                 HHHSEEEETTSS-HHHHHHHHHHHHHH..HHHCHTTCCSEEEEECEEESTTCCCEECCCHHCHHHHTTHHHHHHHHHHHHTSCEEEEEEEEEEEEEEEE CS
        PhyH   2 eedGylviegflsaeevealraeieal..ldralesgdkidfffeekaaadedglleksinkvghflhprkvadlvrailgqdvyvaavlqsmyqdifk 98 
                 + +Gy++i+ ++s +ev++ ++e+ +l    +   +g+  +  fe+ ++++   ll+ks+ + + + hp  v +l + +l  + y    l   ++  + 
  EEA21244.1  41 QVNGYVIIPLAFSRAEVDEAKEELTRLtrSGQGGPAGKVGRNAFEGYKTGRIYALLDKSRIFDKFVSHP-DVLALNDYFLD-PGY----LINAFH-SIS 132
                 679***********************932233445555666778888888888888*************.99888888887.666....444443.333 PP

                 -TTTCB-EEEEE-SGGGST.EES.GCCEEEEEEESS-B-TTBT-EEEETTGGGS-CCGTCCHHCSGCCTTSCCCTTTGHGSCEEEE.BTTTEEEEEETT CS
        PhyH  99 qpkiGgevqpwHqDstflp.tdp.eesvvgvwialedateenGclrfiPGSHkweegplrrrlpeddteaeddeakkedeeeavpvevkaGdavlfhgr 195
                  + +G++ q +H+D+ ++   +p  +  +gv++al+ +te+nG + ++P SH+w  +         +++a+         +ea p++++ G+ v f ++
  EEA21244.1 133 IQ-SGEKHQILHHDDGHVTvPRPhAPFGTGVMVALDAFTETNGSTVVVPKSHLWNSN---------RWPAQ---------NEAFPIVMESGSMVYFLST 212
                 33.5888899******99865557999999************************555.........45555.........88***************** PP

                 SEEEE-TB.SSSXEE CS
        PhyH 196 llHgsgaNrsdksRr 210
                 l+Hg+g+N s   R 
  EEA21244.1 213 LWHGGGENNSGEERI 227
                 **********99885 PP

>> 2OG-FeII_Oxy_3  2OG-Fe(II) oxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.5   0.1   4.1e-06     0.024       8      93 ..     137     231 ..     129     234 .. 0.67

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 4.1e-06
                     TT-EEEEE-SS--..--TT.-.EEEE.EEEEE.....ET-B--EEE.....................---TT-EEEEE-..B-TEEE--B.-SS- CS
  2OG-FeII_Oxy_3   8 egqeykpHvDnfe..keegsgqrrlt.vllyLne.keseeGGelelyekdk...........eavkikpkkgrlvlFesdellpHevlpvtkgge 87 
                     e++++  H+D        +      t v++ L +  + e+ G  ++++k++           ea  i  + g++v+F s+   +H++ + ++g e
      EEA21244.1 137 EKHQILHHDDGHVtvP--RPHAPFGTgVMVAL-DaFT-ETNGSTVVVPKSHlwnsnrwpaqnEAFPIVMESGSMVYFLSTL--WHGGGENNSGEE 225
                     4455666666555542..33334444144455.3222.4556666667777888888888777777778**********65..5*****99888* PP

                     EEEEEE CS
  2OG-FeII_Oxy_3  88 Rlsltg 93 
                     R+sl++
      EEA21244.1 226 RISLNM 231
                     ***986 PP

>> 2OG-FeII_Oxy_5  Putative 2OG-Fe(II) oxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   0.1   4.4e-06     0.026      60      98 ..     191     229 ..     130     232 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 4.4e-06
  2OG-FeII_Oxy_5  60 eenqslvdvkpkeGdlvlFPswlrHevlpnegeeeRisi 98 
                       +++++ +  + G +v F s l+H+  +n++ eeRis+
      EEA21244.1 191 PAQNEAFPIVMESGSMVYFLSTLWHGGGENNSGEERISL 229
                     556778888999*************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (303 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       291  (0.0162307); expected 358.6 (0.02)
Passed bias filter:                      287  (0.0160076); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2245.33
//
Query:       EEA21245.1  [L=483]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.1e-15   56.6  34.3    3.2e-09   36.2  16.3    2.1  2  MFS_1         Major Facilitator Superfamily
     0.0082   15.8   1.9       0.01   15.5   0.2    2.0  2  Ni_hydr_CYTB  Prokaryotic cytochrome b561
  ------ inclusion threshold ------
      0.019   14.7   1.0      0.056   13.1   0.1    2.2  2  SBF           Sodium Bile acid symporter family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2  16.3   5.4e-13   3.2e-09       5     198 ..      72     294 ..      68     333 .. 0.79
   2 !   26.3  10.1   5.6e-10   3.3e-06      42     173 ..     344     474 ..     326     482 .. 0.80

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 5.4e-13
       MFS_1   5 aflsalarsi.......lgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll.fasslwlllvlrvlq 95 
                 +fl+++++++        ++a p   ++++g     +  +  +  +g +v++ ++G+ +d +Gr+  + ++l++ a+++l++  + +++  + ++ ++ 
  EEA21245.1  72 FFLNGFGYAVdsllvvcQSIAQP-SASQEFGNPSKYVAGISLASQIGLLVGAAFWGFSADVIGRKLAFNTSLFACAAFVLIAGgM-PNYISFSAMVAIY 168
                 56666666665555543666666.8999***44444555777799*********************************6666678.89889******** PP

       MFS_1  96 GlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg...............Wravfyilaivsllafvlfllllpeepper 179
                 ++gag+ + + a+ + +  p   ++  + +ls+ +++G+ ++ ll+ +++s+++               Wr++ + ++++ l++ v+ l+ ++  ++++
  EEA21245.1 169 SAGAGGNYILDATNFLEFLPM-SHAWLVTFLSVWWAIGYTIAGLLAWAFLSNFScesdamectaadnmgWRYLHFTCGGLVLVLSVIRLFAVRMAQTPK 266
                 *****************9998.9999999*******************************************************996556666666666 PP

       MFS_1 180 krkspkeee.........kgtgpaplvp 198
                 +  s+ ++e         + + ++p++ 
  EEA21245.1 267 WLTSQNRDEelylillnlSEKYKRPFSL 294
                 6666666657788887774444444443 PP

  == domain 2  score: 26.3 bits;  conditional E-value: 5.6e-10
       MFS_1  42 algaavaslplGrlsdr..fGrrrvlllglllfalglllllfasslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailg 137
                 +l  +++ +++G+l++r  fGrr +l +g++++ +  l  +  +  +   +   +   +++ +++ +++a++ ++ p  +r+ ++gl  + + +G i+g
  EEA21245.1 344 TLSGLLGPIIAGFLVERrwFGRRGTLAVGAAITTVLQLGYT-QIRTPaQNVGISAAITATSNIYYGTIYAYTPEILPSAHRATGYGLCVVLNRVGGIVG 441
                 34456666677*****9877****************55555.3666667889999999999************************************** PP

       MFS_1 138 pllggllasslgWravfyilaivsllafvlfllllp 173
                  l+g++    +  +++ +i+a+++  + v+  lllp
  EEA21245.1 442 VLVGSYAN--VEMTVPLWICAGLYGTL-VFTSLLLP 474
                 *****998..999************99.33344443 PP

>> Ni_hydr_CYTB  Prokaryotic cytochrome b561
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.1      0.49   2.9e+03     127     155 ..     162     199 ..     132     205 .. 0.50
   2 !   15.5   0.2   1.7e-06      0.01      12      74 ..     207     267 ..     202     290 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.49
                   HHHHHH............HTS-THHHHHHH.HHHHHHH CS
  Ni_hydr_CYTB 127 tagfpll.........lddkggaqlarelHellaaall 155
                    a + ++         ld  ++ +++   H +l+ +l 
    EEA21245.1 162 SAMVAIYsagaggnyiLDATNFLEFLPMSHAWLVTFLS 199
                   22222223344444446666667777777766666654 PP

  == domain 2  score: 15.5 bits;  conditional E-value: 1.7e-06
                   HHHHHHHHHHHHHHHHHS------S-GGG-HHHHHHHHHHHHHHHHHHHHHHH---------- CS
  Ni_hydr_CYTB  12 lnallvvllllsgllianlhprlywgdsgkaralHklaGlvllalllfrllwlkkakkpspri 74 
                   ++a+l  +++ls +   ++  + +++d +++r lH+++G ++l+l ++rl+    ++++ p++
    EEA21245.1 207 TIAGLLAWAFLSNFSCESDAMECTAADNMGWRYLHFTCGGLVLVLSVIRLFAV--RMAQTPKW 267
                   68999999999****************999********************999..22222222 PP

>> SBF  Sodium Bile acid symporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.1      0.28   1.7e+03      34      59 ..     198     223 ..     178     228 .. 0.74
   2 ?   13.1   0.1   9.4e-06     0.056     121     170 ..     331     380 ..     321     385 .. 0.85

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.28
         SBF  34 lvlqwvikPllmfilakillrdlkle 59 
                 l + w+i+ +++ +la+++l+ ++ e
  EEA21245.1 198 LSVWWAIGYTIAGLLAWAFLSNFSCE 223
                 44668899999999999999988665 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 9.4e-06
         SBF 121 ttlkvpieeivksvlivviiPliaGillryillkhkGrewfeskllpavs 170
                  +l+vpi e+++++l  ++ P+iaG+l+ + ++ ++G+ ++   + ++++
  EEA21245.1 331 SHLEVPILEMIQTTLSGLLGPIIAGFLVERRWFGRRGTLAVGAAITTVLQ 380
                 578*************************9988888999888877777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (483 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       521  (0.0290591); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 3435.60
//
Query:       EEA21246.1  [L=288]
Description: hypothetical protein PMAA_050640 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (288 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       429  (0.0239277); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.30s 00:00:00.79 Elapsed: 00:00:00.47
# Mc/sec: 1823.35
//
Query:       EEA21247.1  [L=585]
Description: diaminopropionate ammonia-lyase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.1e-55  186.1   0.0    1.2e-54  185.7   0.0    1.2  1  PALP           Pyridoxal-phosphate dependent enzyme
     0.0084   15.8   0.0      0.017   14.8   0.0    1.8  2  Peptidase_M20  Peptidase family M20/M25/M40


Domain annotation for each model (and alignments):
>> PALP  Pyridoxal-phosphate dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  185.7   0.0   1.3e-58   1.2e-54       3     291 ..      35     359 ..      33     362 .. 0.90

  Alignments for each domain:
  == domain 1  score: 185.7 bits;  conditional E-value: 1.3e-58
                 GCSSS--EEEECCTCCCCCCE.EEEEEGGGS.TTSBTTHHHHHHHHHH.................HHTT.TTTSEEEEEBSSHHHHHHHHHHHHHT-EE CS
        PALP   3 lgigpTPlvrlprlskelgvp.lflKlEsln.ptgSfKdRgaeyllar.................lkeg.tgaktvveassGNhgralAaaaallGlkv 81 
                 +g+ +T+l++lp l+ el+v+ +f K+Es +  + SfK++ga++   +                 lke+   +  +++a++GNhgra+A +++ll l  
  EEA21247.1  35 PGYSKTRLIDLPELAMELNVRnVFMKDESDRfGLPSFKILGASWGTFTaicsllglpqdssldhlLKEAtSCNVKLFAATDGNHGRAVARMGRLLSLIT 133
                 68899**************************66**********555554555777777777666544448889************************** PP

                 EEEEETTS-HHHHHHHHHTT-EEEEECCHHHHHHHHHHHHHHHSTTCEE--TTT.......SHHHHHHHHTHHHHHHHHTT...TTEEEEEEE-SSSHH CS
        PALP  82 tivvpadaspekvallrllGaevvevggdydeavaaaaelaaegegaylvsqfd.......nptviegygtiglEileqlg...gkpdavvvpvGgGgl 170
                  i+vp+d     ++l+   Ga+v+ ++gdyd av+aa ++a+ +++ +l+++++        + +++gy+ti  E+ ++l+    ++d++v pvG+G+l
  EEA21247.1 134 SIYVPSDLEDHAKQLISGEGAQVITYDGDYDGAVQAATKAAEITTNGLLIQDTSfpgyediPSSITQGYSTIFREVDDELQlrgLQVDVIVTPVGVGSL 232
                 ************************************99999999**********8766655555************98877778*************** PP

                 HHHHHHHHHH.HSTT.-EEEEEEECTTCGGTTCCS..S.SS..B.SSS.CCSTCSCGTTCCHHHHSEEEEEEEEEEHHHHHHHHHHHHHHHSB-B-HHH CS
        PALP 171 iaGiaaglke.rrpd.vrvigvepegsdalarslragrrvtvpvsdtiadglavgspselafelldrlvdeivtvsdeealeamrllarregivvepss 267
                 ++++++++k  + p+ +rv+ vep+++++++rsl+++ + ++++++ti++g+++g++s  a++ l  lvd   tvsd ea++a++ l  +++i  +p++
  EEA21247.1 233 AHAVVQHYKTlGMPEtTRVVTVEPDTAACFYRSLQRKNPAKISTAHTIMTGMNCGTVSHGAWQDLCHLVDASLTVSDFEAHQAVQYLR-TQKISSGPCG 330
                 **********988889***********************************************************************9.********** PP

                 HHHHHHH.....HHHHHHCCTTCEEEEEE CS
        PALP 268 aaalaal.....klreagelkegdrvvvi 291
                 a ++aal       r    l ++ ++v++
  EEA21247.1 331 ASSVAALrrltiYDRAHLGLHPDTVIVLL 359
                 *******8775545555556666444444 PP

>> Peptidase_M20  Peptidase family M20/M25/M40
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0      0.44     4e+03     136     165 ..     167     196 ..     155     253 .. 0.63
   2 !   14.8   0.0   1.9e-06     0.017     128     206 ..     502     581 ..     230     582 .. 0.83

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 0.44
                    HHHHHHHHHHHH.TSCEEEEEESSSBHTHHH CS
                    xxxxxxxxxxxx.xxxxxxxxxxxxxxxxxx RF
  Peptidase_M20 136 vkalaeaaeelf.gekvelivsgpggtdarf 165
                    v+a+ +aae ++ g+  +++  + g +d++ 
     EEA21247.1 167 VQAATKAAEITTnGLLIQDTSFP-GYEDIPS 196
                    55566665555555444444444.5555543 PP

  == domain 2  score: 14.8 bits;  conditional E-value: 1.9e-06
                    EEEC.CHHHHHHHHHHHHHHHTSCEEEEEESSSBHTHHHH..TTTEEEEEEESSGGCTTSTTTEEEHHHHHHHHHHHHHHHH CS
                    xxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_M20 128 vtln.dsplvkalaeaaeelfgekvelivsgpggtdarff..agiptvmifgpgsglaHspnEyvdledlekgikvlarlle 206
                     +l+  +p+ +++a+aae+++  +v++i       d+  +  +giptv +fgp +++  s +E++d+e+++k  +++ +l+ 
     EEA21247.1 502 LKLDsGHPFERLAAKAAENACEQSVKPIGLR-FRCDTTPLdaNGIPTV-VFGPTGDGLPSDEEWMDVESIRKTERMISSLVA 581
                    5566678888899999999876556666555.88888888899***99.6**88799***************9999988875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (585 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       400  (0.0223102); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.25s 00:00:00.82 Elapsed: 00:00:00.41
# Mc/sec: 4234.58
//
Query:       EEA21248.1  [L=544]
Description: amino acid permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   8.2e-110  367.6  40.1     1e-109  367.3  40.1    1.0  1  AA_permease    Amino acid permease
    2.1e-26   92.7  42.5    2.6e-26   92.4  42.5    1.1  1  AA_permease_2  Amino acid permease
  ------ inclusion threshold ------
       0.31   10.7   9.8        1.2    8.8   0.2    3.3  3  DUF2101        Predicted membrane protein (DUF2101)


Domain annotation for each model (and alignments):
>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  367.3  40.1  1.7e-113    1e-109       1     473 [.      47     506 ..      47     510 .. 0.98

  Alignments for each domain:
  == domain 1  score: 367.3 bits;  conditional E-value: 1.7e-113
  AA_permease   1 hvlvialggviGtglfvglgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgpelGfviGlnylfswitvlaleltaas 98 
                  hv++ia++g+iGtglf+glg+ +s+aGplgall+y+l+g+++ +v  +lge+  ++p++g+f   ++  ++p+l f+iG+n ++  ++ ++ e+ aa+
   EEA21248.1  47 HVQMIAIAGAIGTGLFLGLGKSISTAGPLGALLGYMLVGAIVCAVQFALGEVTALFPVTGSFVRHSEILVDPALCFAIGWNVVYGNFLSVPSEISAAV 144
                  9************************************************************************************************* PP

  AA_permease  99 iliqfwelvtdlpkawvtgavflvvlliinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkga.gfrflgdngsifknnlppgfakeee 195
                   liq+w  ++ ++   v++++f+v+ +++ ++ + vyge+ef++a++ki+ +i+ +i+g ++  gg p k + gf++++++g      ++++ a+ + 
   EEA21248.1 145 VLIQYW--NDNIN-PAVWVTIFIVLSTLVAVIFIGVYGEVEFFFAVLKILLVIGIVIMGLVIDLGGVPGKPRlGFQYWNAPGP-----FVEYIAEGSW 234
                  ******..77777.*********************************************************9***********.....6666556699 PP

  AA_permease 196 gafknfisvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasa.aspfvifikesgvsvlapli 292
                  g+f++f +v++ +v +f+G e++a++a+E+k+P+ +iPka ++v+ ritifYvl++l++g+lv+ +d  l nds +a  spfvi+ + +g++++++++
   EEA21248.1 235 GQFLGFWAVMSNAVYSFAGVESLAMAAAETKNPRHNIPKACKRVFARITIFYVLAILIVGMLVSSDDERLSNDSGTAaQSPFVIAASDAGIKAIPSIV 332
                  9**************************************************************************9999******************* PP

  AA_permease 293 naviltaalssansslysasRvlyslakdglaPkvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliilsylrf 390
                  nav+lt+a+ss+n ++ +++R+ly la  g+aPk++ + + +g P++ +++ +++s+l++++ s  +   +vf +ll ++a+  l++w+ i+l+++r+
   EEA21248.1 333 NAVVLTSAWSSSNQAILAGTRTLYGLAVKGHAPKFFLWTTPYGIPYMCVAAQIAFSFLGYMCVSNDAL--NVFYWLLDLTAAGVLVCWITISLNHIRL 428
                  ************************************************************99888888..**************************** PP

  AA_permease 391 Rkalkyqgrsieelgfkaallplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfliilvgvklhvknk 473
                   +alk+qg  +  l+ +    p+g++++l++++iill+ +++ ++      ++w+++sf+++yl ++l+l+ + ++k+  ++k
   EEA21248.1 429 IQALKIQGYPLHVLPWHNSWTPYGSWFALVSCVIILLTGGFTVFTS-----GNWDPSSFVSSYLDIPLVLVAFGVYKFLRRTK 506
                  **********************************************.....9*************************998876 PP

>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.4  42.5   4.4e-30   2.6e-26       5     407 ..      47     475 ..      43     496 .. 0.74

  Alignments for each domain:
  == domain 1  score: 92.4 bits;  conditional E-value: 4.4e-30
  AA_permease_2   5 safalvigsvigsgifvkn..laasggpa..lilwvwiavligslavllvyaElssalprsgGiyvytkaafgkkvaflsawfnwfayvpvlasil 96 
                     + +++i  +ig+g f     ++ ++gp+  l+ + ++++++   av +++ E+++++p  g  +  ++++  + + f  +w  +++ +++++s +
     EEA21248.1  47 HVQMIAIAGAIGTGLFLGLgkSISTAGPLgaLLGYMLVGAIV--CAVQFALGEVTALFPVTGSFVRHSEILVDPALCFAIGWNVVYGNFLSVPSEI 140
                    5668899999****9998888677777764144444444444..49********999*************************************99 PP

  AA_permease_2  97 svaasyllnalgpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfssl....stetdt....... 181
                    s+a+  +++ ++ ++++  w t++   ++l +  l+ ++ i  ++ + ++ ++lkil ++i ++i gl++   gg + +     + ++        
     EEA21248.1 141 SAAVVLIQY-WNDNINPAVWVTIF---IVLST--LVAVIFIGVYGEVEFFFAVLKIL-LVIGIVIMGLVID-LGGVPGKprlgFQYWNApgpfvey 228
                    999999999.67788777666666...23333..333335566999**********5.6666666888884.444444446673444334443332 PP

  AA_permease_2 182 ffpngwpg...vllgllivlwsfdGfesaanvseevkk.k.dvpkaifigllivlvlyll.vniaflgvvpddeianlsnlgsv....aalffeav 267
                    +  + w +   ++++++ +++sf+G+es a  + e k+ + ++pka+  +++ ++++y+l + i+ + v++dde  ++ ++g++    + + +  +
     EEA21248.1 229 IAEGSWGQflgFWAVMSNAVYSFAGVESLAMAAAETKNpRhNIPKACKRVFARITIFYVLaILIVGMLVSSDDERLSN-DSGTAaqspFVIAASDA 323
                    333344433335999999*****************9998559*****9999999999998345555668888887433.33433222277777778 PP

  AA_permease_2 268 ggkvvaiivvilialsllgaintavigssrvlealardgvlPrffakvnkfgspiraiiltaivslillllfllas..saaynfllsvsslgliis 361
                    g k+  +iv++++  s++ + n a+++ +r+l+ la  g  P+ff  + ++g+p+ ++  +  +s++ ++ +  ++   + +++ll++++ g++++
     EEA21248.1 324 GIKAIPSIVNAVVLTSAWSSSNQAILAGTRTLYGLAVKGHAPKFFLWTTPYGIPYMCVAAQIAFSFLGYMCV--SNdaLNVFYWLLDLTAAGVLVC 417
                    8889999**********************************************************6665333..222445666************* PP

  AA_permease_2 362 yllliigalilrkkrphlkr............pgkilvaiigalfllfllvalffppk 407
                    ++ +++  + l    ++++             p+  ++a+++++++l++  ++ f + 
     EEA21248.1 418 WITISLNHIRLIQALKIQGYplhvlpwhnswtPYGSWFALVSCVIILLTGGFTVFTSG 475
                    ****999888888888773334666556766655556777777777777666666544 PP

>> DUF2101  Predicted membrane protein (DUF2101)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   4.4      0.35   2.1e+03      73     127 ..     145     199 ..     138     205 .. 0.75
   2 ?    8.8   0.2   0.00019       1.2      80     132 ..     367     419 ..     354     428 .. 0.89
   3 ?    4.6   0.0    0.0039        23      83     141 ..     447     508 ..     438     531 .. 0.73

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.35
     DUF2101  73 ilirniellidfeayrafylavsviailaylgyvllrklslelyyylvyllvivi 127
                 +li++++  i++  + + ++++s+++ + ++g     ++ +++   l  ++++++
  EEA21248.1 145 VLIQYWNDNINPAVWVTIFIVLSTLVAVIFIGVYGEVEFFFAVLKILLVIGIVIM 199
                 6788888888888888889999999999998888777777777777776666654 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.00019
     DUF2101  80 llidfeayrafylavsviailaylgyvllrklslelyyylvyllvivivvlvf 132
                 +++   +y   y+ v+  +  ++lgy+ + + +l+++y l  l+++ + v  +
  EEA21248.1 367 FFLWTTPYGIPYMCVAAQIAFSFLGYMCVSNDALNVFYWLLDLTAAGVLVCWI 419
                 66777899999**********************************99998765 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.0039
     DUF2101  83 dfeayrafylavsviailaylgyvllrklsle...lyyylvyllvivivvlvfryyfksryg 141
                 ++ +y  ++  vs ++il  +g+ +  +   +   ++  +  + +++++  v+++  +++y+
  EEA21248.1 447 SWTPYGSWFALVSCVIILLTGGFTVFTSGNWDpssFVSSYLDIPLVLVAFGVYKFLRRTKYV 508
                 5789999****************999886655100555556666666666666777788887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (544 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       773  (0.0431145); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.44
# Mc/sec: 3707.72
//
Query:       EEA21249.1  [L=447]
Description: rhamnogalacturonase A precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      3e-21   75.9   3.0      4e-21   75.4   3.0    1.1  1  Glyco_hydro_28   Glycosyl hydrolases family 28
     0.0002   21.3  12.7    0.00067   19.6   9.6    2.9  2  Pectate_lyase_3  Pectate lyase superfamily protein


Domain annotation for each model (and alignments):
>> Glyco_hydro_28  Glycosyl hydrolases family 28
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.4   3.0   4.4e-25     4e-21      56     319 ..     120     375 ..      76     381 .. 0.84

  Alignments for each domain:
  == domain 1  score: 75.4 bits;  conditional E-value: 4.4e-25
  Glyco_hydro_28  56 gekitvlgisGkgtidGqGqawwdgkgkkkkegkkkpkflvikkvknskiknlniknspvfhfsvesgkdltisditidasagdhNtDgidvgss 150
                      ++ ++    G g i G G ++        k+g+  p++l++ +v+n+ i+++   +sp fh+ +  +++  + +++i    ++   Dgid+   
      EEA21249.1 120 STDFEIYSSRGVGAIQGYGYQFH-------KQGQYGPRLLRLYDVTNFAIHDIAFVDSPAFHLTLDTCNQGEVYNMIIRGG-NKGGLDGIDLWG- 205
                     45555666667777777776664.......567899***************************************999765.45689****986. PP

  Glyco_hydro_28 151 kgvtisntnikngDDciainsgsknisitnvtcggGHGlSiGSvggrsdntVknvtvkdskvknsenGvRIKtikgatgtvsnvkyeniklknva 245
                       + +++  ++n D c+ +++ s++i+++n++c+   G  +GS+g+    +++ +  ++   +ns+     K+++g +g+v++v+ +n   ++ a
      EEA21249.1 206 FDIWVHDVEVTNKDECVTVKNPSNHIQVENIYCNWSGGCGMGSLGND--TNISKILYNNIYTVNSNQMFMFKSNSG-SGEVTDVTLQNFIGHENA 297
                     57********************************999999*****88..88*********************9876.79**************** PP

  Glyco_hydro_28 246 ypividqdYenkeptgkptsgvkisdvtfknvtgtvks.aea..vkllcekgskcsdvtmsdvkitg..g.kstskcknv 319
                     y + ++  Y  +  + +  sg+  + +tf+n +gt ++ a++  +++ c + + c+++ ++d ++    g  ++ kc n+
      EEA21249.1 298 YSLYLNA-YWSGLAS-QGGSGILYNSITFNNWKGTCANgAQRppLYVWCPSTNACTNIIIEDFNMWTesGsTEYYKCANA 375
                     ***9986.5554444.4459****************9987644499******************9654234667788875 PP

>> Pectate_lyase_3  Pectate lyase superfamily protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   9.6   7.5e-08   0.00067       3     199 ..      44     279 ..      42     299 .. 0.60
   2 ?   -0.9   2.2      0.13   1.2e+03     127     167 ..     285     328 ..     250     377 .. 0.55

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 7.5e-08
                      EGGGGT---EEEEE-HHHHHHHH......HTSS-EEE-SEEEEESS-E.........EE-SSE.EEEES-.TTTEEEEE-TT-.....SS--SE CS
  Pectate_lyase_3   3 nVkdyGakgDGvtDdtaaiqkaiscasatttgavVYfPaGtYlvsspi.........ilksgv.qLvGdg.ngrpvlkaaaaf.....vgagli 80 
                      ++++yGa+ DG+tD   ai +a    +a ++g+vV +P Gt+ +++ +         i+ +g+ + +G +  ++  +  +++f     +g g i
       EEA21249.1  44 DITHYGAVADGKTDAGPAILAAF---EACASGGVVNIPLGTFAMATWVtlkggnawaINLDGIlVRTGTAgGNMIYIVHSTDFeiyssRGVGAI 134
                      89*********************...*********************97888777763333331223433355666666777788999999999 PP

                      EES-TTT-................-EEEEEEEEEEE.GGGG-SS---SSEEEES-EEEEEEEEEEES-SSEEE-SSS................. CS
  Pectate_lyase_3  81 dgdpyvsg..gs............ealiatnnfyrq.irnlkiditavapgatgihwqtaqatslenvefemseasg................. 142
                      +g  y+ +  g+            +  i++  f+++ +  l+                t+ + +++n++++  ++ g                 
       EEA21249.1 135 QGYGYQFHkqGQygprllrlydvtNFAIHDIAFVDSpAFHLT--------------LDTCNQGEVYNMIIRGGNKGGldgidlwgfdiwvhdve 214
                      999999552332333444444443333333333333333333..............34555555666555555555422333333333333333 PP

                      ..---TT---SS--EEEE.ES-EEES-SS-SEEE.S....-EEEEEES-EEE-S--SEEE-TT-E CS
  Pectate_lyase_3 143 ..tkhqgifiengsggfl.ndlvfsglgdigiav.g....nqqftvrnitfnnattgievlwgwg 199
                        +k + ++++n+s+++  +++  +  g+ g+   g      ++  +ni++ n+++ + +++++g
       EEA21249.1 215 vtNKDECVTVKNPSNHIQvENIYCNWSGGCGMGSlGndtnISKILYNNIYTVNSNQMFMFKSNSG 279
                      33333356688888877667777777777777774433323344445555555555555555554 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.13
                      EEEEES-SSEEE-SSS---T...T---SS--EEEEES-EEES-S CS
  Pectate_lyase_3 127 atslenvefemseasgtkhq...gifiengsggflndlvfsglg 167
                      +++l+n++ + + +s + +    g+  + gsg  +n ++f++  
       EEA21249.1 285 DVTLQNFIGHENAYSLYLNAywsGLASQGGSGILYNSITFNNWK 328
                      33333332222223322222222444444444444444444433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (447 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       401  (0.022366); expected 358.6 (0.02)
Passed bias filter:                      283  (0.0157845); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 3032.73
//
Query:       EEA21250.1  [L=344]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      9e-07   29.4   0.1    1.8e-06   28.5   0.1    1.5  1  4HBT_2    Thioesterase-like superfamily


Domain annotation for each model (and alignments):
>> 4HBT_2  Thioesterase-like superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.5   0.1   9.8e-11   1.8e-06       7     100 ..      89     191 ..      83     236 .. 0.78

  Alignments for each domain:
  == domain 1  score: 28.5 bits;  conditional E-value: 9.8e-11
      4HBT_2   7 Dlnghlnnarylryleearvkfle......rtglksrsiarrgi....glilssahvryrrplkfpdrltvefrvididaktliiehrflsnadgkk.. 93 
                 D+n h  n++y+  l++ r  +l+        ++ ++++a++g      ++l+s+   ++r+++ +  ++v +r+  +d+k+l+i   f++  ++k+  
  EEA21250.1  89 DFNLHKSNSTYFTDLDSSRSLLLSflvfhgMSKT-HKELAAEGRngvmTVMLGSTYRNFKREIQTGYPYEVWSRILTWDQKWLYIVTHFVR--KDKIvp 184
                 89**********99*****988877776653333.4444444333345899999999**********************************..666633 PP

      4HBT_2  94 aarveer 100
                  a+v+e+
  EEA21250.1 185 KASVTEV 191
                 4555443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (344 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       382  (0.0213063); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2458.38
//
Query:       EEA21251.1  [L=584]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.5e-30  103.8  44.8    1.1e-28  100.3  44.8    2.0  1  Acyl_transf_3  Acyltransferase family


Domain annotation for each model (and alignments):
>> Acyl_transf_3  Acyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.3  44.8   6.3e-33   1.1e-28       2     330 ..       5     437 ..       4     447 .. 0.82

  Alignments for each domain:
  == domain 1  score: 100.3 bits;  conditional E-value: 6.3e-33
                    xxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxx...............xxxxxxxxxxx RF
  Acyl_transf_3   2 aylDllRgiAillVvflHali....ayspdagrgspiqasqssqi.....aflggfgvplFFllSGffla...............amlyrrrglsk 73 
                    ++lD+lRgiA+ +V f H+++    +     +  +p+ ++ ++q+     +f+ + +v+lF+++SG+ ++               + +     ls+
     EEA21251.1   5 KWLDGLRGIAAAIVAFDHFFMgdiwHPFLSFWADPPEDNRRFIQLppiriLFSAHAMVTLFMVISGYAISinlvkareqqnhmlqRGQPFLNRLSS 100
                    79*******************99984455556666677777777799**********************************777655555667999 PP

                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Acyl_transf_3  74 likrRilrlliplliwllliillialvaghiqanasanvtlfdet................kglmfllfefpatghlWfLwalfvlylllplllrl 153
                    +++rRi+r+++p+l+ +++  ll+++  +h + +  ++     +t                + +  ++  ++++g+lW+++++  ++++++l++  
     EEA21251.1 101 AVMRRIFRIYLPVLVISIISQLLFFFNLYHWTFDDGVLRGIKPWTsplahvkwliiymmdsMNMIAFEYNGGFNGQLWTMPVEYRGSCVIYLFVIG 196
                    **********999999999888888877666665555555555668**************999999999*************************** PP

                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.................................xxxxxxxxxx.xxxxxxx RF
  Acyl_transf_3 154 lrkvrkshlllllilllllslvfirhelfgpatsvgllplpsvla.................................llfflfGall.adaddrd 215
                    l+++++  +l++l +l++++l+++++  fg+ ++++l+   ++                                    +  + G ++ +++  + 
     EEA21251.1 197 LAGWKRNLRLWILPALAIYFLWYGIWDVFGFLWGLWLAERTVGGNgsgehratehgmhtldemnnadddefdepgkllTVHRFPGQYYwRRYIAKS 292
                    ********************************9999876655555******************************998888888865504444455 PP

                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxx RF
  Acyl_transf_3 216 rnlsrglkislllsllllalillalfgqtdg........gglvasvliqsaslllvslgimllllllfalpsrsafk...llrylgkiSygiYliH 300
                    r   +  ++ ++++++++ l +l+  g+  +        +++ + +++q +++++ s+g++ll++++  ++ +++ +    ++ylgkiS+++Yl+H
     EEA21251.1 293 RMTLMSDILTAVAFIMGFHLLCLGDDGHLTPgyqwltalNSSKWKDNWQVYHWCWKSVGAALLVYAVSNSRMLQQPLntaFVQYLGKISFSLYLVH 388
                    5555555555555555555555555555554999*****9**********************************88899***************** PP

                    xxxxxxxxxxxxxx...........xxx.........xxxxxxxxxxxxx RF
  Acyl_transf_3 301 lpllmllqkllrdw...........gln.........lgevlllvlllvv 330
                    + +++l++  +r w           g           l +++ +++l ++
     EEA21251.1 389 QAIYHLWREPVRNWlyltingnpypG-TvgadpiafhLAWWISALILGPI 437
                    **************877776544440.04444544444444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (584 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       509  (0.0283898); expected 358.6 (0.02)
Passed bias filter:                      314  (0.0175135); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.26s 00:00:00.86 Elapsed: 00:00:00.44
# Mc/sec: 4030.64
//
Query:       EEA21252.1  [L=511]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-07   30.0   0.7      1e-05   25.1   0.9    2.6  2  Fringe    Fringe-like
     0.0026   17.6   1.9     0.0057   16.5   1.9    1.5  1  PAN_4     PAN domain
  ------ inclusion threshold ------
      0.037   13.4   0.1      0.069   12.5   0.1    1.4  1  DUF604    Protein of unknown function, DUF604


Domain annotation for each model (and alignments):
>> Fringe  Fringe-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0      0.23   1.4e+03       6      48 ..     114     159 ..     110     179 .. 0.65
   2 !   25.1   0.9   1.7e-09     1e-05      84     163 ..     227     290 ..     218     328 .. 0.79

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.23
      Fringe   6 ddifiavkttkkfhkeRlelllkTwi...srakeqtfiftdvedee 48 
                 +++ + +kt      +Rl++ l T     + a e+t+i++dv d  
  EEA21252.1 114 SEVALLLKTGASLVWKRLPIHLLTSLapeRIAAENTIIYSDVPDVI 159
                 55666667777777778877666654122457899999**999865 PP

  == domain 2  score: 25.1 bits;  conditional E-value: 1.7e-09
      Fringe  84 eskkkWfchvDDDnylnveaLlklLskynhtqdvylGkpsldrpieaterteenkkkkvkfwfatGGaGfclsralalkl 163
                 + + kW++ + DD ++ +++Ll+ L+++++++ +y+G   +++  e                fa+GGaGf lsr+  +k 
  EEA21252.1 227 QPDAKWYIYMEDDAFIFLPNLLQHLATFDWKDAWYIGSLAVKHG-E---------------IFAHGGAGFALSRGAWEKT 290
                 4567*********************************8877652.2...............599**********998887 PP

>> PAN_4  PAN domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   1.9   9.5e-07    0.0057      16      39 ..     445     468 ..     433     478 .. 0.85

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 9.5e-07
       PAN_4  16 dspeaCcaaCaadsnCnawvyvkp 39 
                  s ++C++aC a+++C+ w++  +
  EEA21252.1 445 ESVDDCEEACLAWPECVQWSFYED 468
                 4789*****************875 PP

>> DUF604  Protein of unknown function, DUF604
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.1   1.1e-05     0.069       9      93 ..     273     366 ..     266     379 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.1e-05
      DUF604   9 mafGGgGfaiSyplakaLakvldeClerYpkly....gsddriqaClaelGvpltkekGfHqvDlrgdllGlL.....aahplaplvslHHlda 93 
                  a+GG+Gfa+S    ++   + ++ +e+Y++++      d+ +   l + Gv++ + +   q+ +  +           a+  +p+ s+HH++ 
  EEA21252.1 273 FAHGGAGFALSRGAWEKTFGTDKDIIEKYENFTeahgCGDHVLGHVLKDHGVSFGETHEAEQFTFGFNPESYWnmwygKANWCKPIFSMHHMHL 366
                 69****************************99833323588999999*****997776666666554443322111226788999999999865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (511 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       596  (0.0332422); expected 358.6 (0.02)
Passed bias filter:                      465  (0.0259356); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.43
# Mc/sec: 3555.42
//
Query:       EEA21253.1  [L=596]
Description: hyaluronan synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.6e-09   37.3   2.9    2.6e-09   37.3   2.9    2.0  3  Glyco_trans_2_3  Glycosyl transferase family group 2
    2.9e-06   27.3   0.1      7e-06   26.1   0.0    1.6  2  Glyco_tranf_2_3  Glycosyltransferase like family 2
    2.9e-06   26.2   4.7    1.5e-05   23.9   1.1    2.8  2  Chitin_synth_2   Chitin synthase
    1.1e-05   25.0   0.1    6.7e-05   22.4   0.1    2.0  1  Glyco_transf_21  Glycosyl transferase family 21


Domain annotation for each model (and alignments):
>> Glyco_trans_2_3  Glycosyl transferase family group 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0       1.9   8.5e+03     122     137 ..      45      67 ..      35      68 .. 0.80
   2 !   37.3   2.9   5.8e-13   2.6e-09       6     188 ..     266     464 ..     265     481 .. 0.71
   3 ?   -2.9   1.0       1.2   5.5e+03     163     182 ..     550     577 ..     520     595 .. 0.38

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 1.9
  Glyco_trans_2_3 122 vkeksplt.......lraalrQr 137
                       ++k+plt       + a+++++
       EEA21253.1  45 GYTKFPLTldlmisiFVAEYNRW 67 
                      58899999888888888888888 PP

  == domain 2  score: 37.3 bits;  conditional E-value: 5.8e-13
  Glyco_trans_2_3   6 DaDtvlppdclreiaaela.spevaivq.gpvlvmnvanwleelaalffaedhgkdilvrealgrvvpsvGsgaflrrsalq.........evg 88 
                      D+Dt + pd+l +++a +a + +++ ++ g ++ ++  +++++l  + +    +  ++ ++++g      G  +++r+sal          +v 
       EEA21253.1 266 DSDTIVLPDSLQKTIATVAgDENAGGASsGLIVHNEHDTLWTKLGSAVYWCELYLTRSTSASSGTSDCQSGPSTVFRISALPgvlycwytqKVL 359
                      9******************888888776255555688999999999998444454555555555555556************444444444443 PP

  Glyco_trans_2_3  89 gwdgdessvsEDfdmglrlqrkGyrvrfvpeslvkekspltlraalrQrkRwayGc..el...eklillvrllgylgsllwsalplhlallllf 177
                      g +     v ED ++  +l+ +G++v +v+++l+ + +p tl  +l Q  Rw +    e     k++ll +++ +++    +  pl +++++l+
       EEA21253.1 360 GKR---MIVNEDRHLTTNLLLRGWTVTYVSDTLTATDTPTTLSRWLLQQVRWGRAThiETfqqPKVYLLNHPVFFWAAMKREVGPLIVFFSILY 450
                      444...69***********************************************854225634444444445555555566666655555555 PP

  Glyco_trans_2_3 178 slla...lalvlll 188
                      +l+    ++++ ++
       EEA21253.1 451 YLITghpFVYFCWW 464
                      54444444444443 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 1.2
  Glyco_trans_2_3 163 lwsalp....lhlallllfslla....l 182
                      lw++++    +++a+ ll++  +     
       EEA21253.1 550 LWMGILggtcARIAGGLLSWSDIvifrA 577
                      2222222221223333333222222221 PP

>> Glyco_tranf_2_3  Glycosyltransferase like family 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       1.2   5.5e+03      36      71 ..     138     172 ..     117     198 .. 0.68
   2 !   26.1   0.0   1.6e-09     7e-06      92     229 ..     263     410 ..     252     411 .. 0.87

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 1.2
  Glyco_tranf_2_3  36 vvvdesdaetlevaeelaaalpdvrvrvvvnarnlg 71 
                      v+vd+++a+  ++++ ++  +p++   v++ ++ lg
       EEA21253.1 138 VGVDGDQAADMDMVRVFQMVYPKES-AVIHLDEPLG 172
                      5566666666666666666666643.4455555444 PP

  == domain 2  score: 26.1 bits;  conditional E-value: 1.6e-09
  Glyco_tranf_2_3  92 llvDdDtvvePdtlkrllqff.ltpkvgavgtpvflln.rstlvsal.galefaerhlrflaarralgvltlnGsgslirrevlkele...... 176
                      +  D+Dt+v Pd+l+++ +++  ++++g +     ++n  +tl++ l  a++  e +l ++  + +++ ++ +G  +++r + l          
       EEA21253.1 263 WSSDSDTIVLPDSLQKTIATVaGDENAGGASSGLIVHNeHDTLWTKLgSAVYWCELYLTRSTSASSGTSDCQSGPSTVFRISALPGVLycwytq 356
                      668***************999889999999988888875668888884555777777777777777778**************99999999998 PP

  Glyco_tranf_2_3 177 .gldplflltdDyelglrlrragfrtayvpgaavrevfpsslkayikqrnRwvy 229
                        l+++ ++ +D +l+  l  +g+ + yv + ++ + +p++l++   q  Rw +
       EEA21253.1 357 kVLGKRMIVNEDRHLTTNLLLRGWTVTYVSDTLTATDTPTTLSRWLLQQVRWGR 410
                      5455599999******************************************76 PP

>> Chitin_synth_2  Chitin synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   1.1   3.3e-09   1.5e-05     176     372 ..     233     410 ..     227     423 .. 0.80
   2 ?   -0.1   0.1     0.061   2.7e+02     467     506 ..     495     537 ..     490     545 .. 0.80

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 3.3e-09
  Chitin_synth_2 176 fdermteleyelfkkikkviGvspdfyeivlmvdadtkvapdsltrlvaalvkdpeilglcGetkiankkeswvtaiqvfeyyishhlskafesv 270
                     ++ +m +  + +   i  ++  +  + e +   d+dt v pdsl++ +a+++ d++  g      + n++++ +t +    y+    l+++  + 
      EEA21253.1 233 YEPHMHKKAIMFTSFIFSIVISEILNIEFMWSSDSDTIVLPDSLQKTIATVAGDENAGGASSGLIVHNEHDTLWTKLGSAVYWCELYLTRSTSAS 327
                     6666777777777778888888888999******************************************************************* PP

  Chitin_synth_2 271 fGsvtclPGcfslyrikaakgadgkwvPilvspeiveeysenvvdtlhkknllllGedryltt.lllktfpkrktvfvpqakcktvaPdtfkvll 364
                      G+  c  G  +++ri a  g                 y+  + + l k+  + + edr+ltt lll+ +     ++v ++ + t +P t +  l
      EEA21253.1 328 SGTSDCQSGPSTVFRISALPGVL---------------YCWYTQKVLGKR--MIVNEDRHLTTnLLLRGW---TVTYVSDTLTATDTPTTLSRWL 402
                     *****************998822...............333333445554..345677777763445544...4567777777777777777777 PP

  Chitin_synth_2 365 sqrrrwin 372
                      q+ rw  
      EEA21253.1 403 LQQVRWGR 410
                     77777755 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.061
  Chitin_synth_2 467 lalPifnfvlPlyafwhlddf...swGetrvveGekkkkaage 506
                      al  +n+ lP+   w +       wG t + + e +k+++++
      EEA21253.1 495 PALLFYNLPLPAIQIWSMATVlegGWGTTMRSNSEMSKQNQSQ 537
                     4677899**********98653338******999999998876 PP

>> Glyco_transf_21  Glycosyl transferase family 21
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.4   0.1   1.5e-08   6.7e-05      32     173 .]     260     410 ..     251     410 .. 0.78

  Alignments for each domain:
  == domain 1  score: 22.4 bits;  conditional E-value: 1.5e-08
  Glyco_transf_21  32 dllvisDsdvrvkpdyLeellaaled..pkvglVtslpvgsdakglaaaleaafl..ntlagvlqa.klsglgfavGksmalrreaLeaiGGfe 120
                      ++++ sDsd++v pd L++  a+++   ++ g  ++l+v  ++++l+++l +a    + +  + ++ + +  ++  G s ++r +aL  +    
       EEA21253.1 260 EFMWSSDSDTIVLPDSLQKTIATVAGdeNAGGASSGLIVHNEHDTLWTKLGSAVYwcELYLTRSTSaSSGTSDCQSGPSTVFRISALPGVLYCW 353
                      68899*************988888764345566777999999********77775566555555553456779999**********98765443 PP

  Glyco_transf_21 121 aladeLA......eDyalgkllraaGlkvvlspapiaqtsvprrsslrallaRqlrWar 173
                        ++ L       eD  l++ l  +G++v  +++++  t++p+  +l+ +l +q+rW r
       EEA21253.1 354 YTQKVLGkrmivnEDRHLTTNLLLRGWTVTYVSDTLTATDTPT--TLSRWLLQQVRWGR 410
                      3333332222234**********************99999985..99**********65 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (596 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       509  (0.0283898); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.66u 0.28s 00:00:00.94 Elapsed: 00:00:00.49
# Mc/sec: 3676.43
//
Query:       EEA21254.1  [L=101]
Description: hypothetical protein PMAA_050720, partial [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (101 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       812  (0.0452898); expected 358.6 (0.02)
Passed bias filter:                      514  (0.0286686); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.28s 00:00:00.71 Elapsed: 00:00:00.45
# Mc/sec: 669.29
//
Query:       EEA21255.1  [L=581]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (581 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       617  (0.0344135); expected 358.6 (0.02)
Passed bias filter:                      449  (0.0250432); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.47
# Mc/sec: 3692.48
//
Query:       EEA21256.1  [L=562]
Description: general amidase GmdA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-99  334.3   0.0    1.7e-99  333.8   0.0    1.2  1  Amidase   Amidase
  ------ inclusion threshold ------
       0.17   11.9   0.0       0.38   10.7   0.0    1.5  1  DUF807    Coxiella burnetii protein of unknown function (DUF8


Domain annotation for each model (and alignments):
>> Amidase  Amidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  333.8   0.0  1.9e-103   1.7e-99       1     451 []      85     550 ..      85     550 .. 0.88

  Alignments for each domain:
  == domain 1  score: 333.8 bits;  conditional E-value: 1.9e-103
                 HHHHHHHHHHHHHHHHH--EEEEEHCCCCHHHHT---TTT.......TTTT-EEEEETTB--TTSB--TTSGGGTT-B-.........SS--HHHHHHH CS
     Amidase   1 elveaflkrieavneklnalvtvfieealaqAakldkkra.rgkekgpLhGvPisvKDnidvkgvpttaGskalenypa.........ekDatvverLk 89 
                 e+ eaf++r++ +++ +n+l+++f+++ala+A++ d + a ++k+ gpLhG+P+s+KD+++vkgv+tt+G+  + +             +++++v+ L+
  EEA21256.1  85 EVAEAFCHRAALAHQLTNCLHEIFFDAALADAQAQDNYFAtHKKPIGPLHGLPVSLKDQFHVKGVETTMGYIGWMGTFEglrgtgkelVYESEMVRELR 183
                 7899********************************************************************997654322222211268********* PP

                 HTT-EEEEEE--SGGG-SSSSTT-TT---BBTTCTCCB--SSSHHHHHHHHTTSSSCEEEEESSSTTHHHHHHCTSEEEE--TTSC--TTB-....-SS CS
     Amidase  90 kaGavilgkTnmdefamgsstensvfgptrNPwdksrtpGGSSGGsAAavAaglvplaiGtDtGGSiRiPAsfcglvGlKPtygrvSragvv....ale 184
                 + Ga++++kT ++ ++m  +t n+++g t  P ++  ++GGSSGG++A+++ +++p++ GtD+GGSiRiPA+f+gl+Gl+P+ gr++++g+     ++ 
  EEA21256.1 184 SLGAILYCKTAVPHTLMAGETVNNIIGYTWSPKNRLLSAGGSSGGEGALIGFKGSPVGFGTDIGGSIRIPAAFNGLYGLRPSAGRLPYEGMAnsmdGQN 282
                 *************************************************************************************************** PP

                 TTT-EEEEEESSHHHHHHHHHHHBS--TT-TTS----HHHHHHHHCTT---TT-EEEEEGGGCSS---CCHHHHHHHHHHHHHCTT-EEEEEE-CCGGG CS
     Amidase 185 ssldvvGplarsvedlalllrvilgedpkdstssvipeesedlaeelkkslkglriGvvkedgvasldpevqravekalkaLeeaGhevvevelpslee 283
                 s l+vvGpl++sv  l+ll++ +l ++p+  + +v+      ++     s  +l  G+ k+dg ++++p+v+ra+++++ a ++aGh+v e+++ps++e
  EEA21256.1 283 SVLSVVGPLSTSVGSLRLLVQSLLSQEPWLHDPLVLE---LPWRDVPDLSGTPLTFGIFKDDGIVKPHPPVARAIDMVVTAINRAGHQVMEWSPPSHTE 378
                 ******************************9999965...4555555566678********************************************** PP

                 HHHHHHHHHHHHHHHHTTT-SSSSS---SS-SCCCCCCCHHHHCCS-HHHHHHHHHHHHHCSCCCCCCCHHHHHHHHHHHHHHHHHHCCCBSEEEEESS CS
     Amidase 284 alslyylilvaeassnlarylgvryerlsetkvlsellpksraellgeevkrrielgnyalsaeasskyylkaqkvrrllrrefakafeelDvllsPta 382
                  ++l+++++v+++++ + +  g   e    ++++ +++ ++ +++ + +  + i+  +     ++    y+k++ + ++ + e+++  +++D+ ++P+a
  EEA21256.1 379 GIRLVNEVYVLDGGHDVHSAFGLTGETV--ADQIVTMYGRTPTSEKSASYIAAINIEK-----RN----YQKQYLEYWNSTTELTGTGRAVDAFIMPVA 466
                 **************99876655533222..2222345555554444444444444433.....22....677777777778888888888********* PP

                 SSS--BCCCCCHHHCSHHHHHGCCTTT...HHHHHTT--EEEEECCCCT..................TECEEEEEEESTT-HHHHH CS
     Amidase 383 ptpaprlgekdktidsytvlynlldftavvvpvnlaglpalsvpagksed.................glPvGvqvigkafqeetlL 451
                 +++a r +  ++++  y++++nlld+ + + pv++++++ ++  ++ + +                 g+ v+vqv+++++qee++L
  EEA21256.1 467 AIAAARPKLYNYYG--YSTIINLLDYASCTLPVTTVDKDVDQFDSNHEPRnkvdeiawksydpeiydGAHVSVQVVARRLQEERVL 550
                 ********999987..**************************8888885568999*****************************98 PP

>> DUF807  Coxiella burnetii protein of unknown function (DUF807)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   4.3e-05      0.38      35      83 ..      45     101 ..      37     109 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 4.3e-05
      DUF807  35 ekiatgkytitllsardvketqpavvhisvqd........evneafcsrlvkalkft 83 
                 +k  tg+y   +l+a++v+ t+  +  i ++         ev eafc r + a ++t
  EEA21256.1  45 QKDVTGEYIRQFLTAKEVEITETDACDIVLRTasgawkarEVAEAFCHRAALAHQLT 101
                 7899**************999999999877532222333389999999988887776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (562 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       353  (0.0196888); expected 358.6 (0.02)
Passed bias filter:                      318  (0.0177366); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.48
# Mc/sec: 3485.13
//
Query:       EEA21257.1  [L=388]
Description: pentalenene synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.9e-11   43.9   0.1    3.6e-11   42.9   0.1    1.4  1  Terpene_synth_C  Terpene synthase family, metal binding domai
  ------ inclusion threshold ------
      0.022   13.6   0.3      0.037   12.9   0.1    1.5  2  TRI5             Trichodiene synthase (TRI5)


Domain annotation for each model (and alignments):
>> Terpene_synth_C  Terpene synthase family, metal binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.9   0.1     4e-15   3.6e-11      21     263 ..      77     321 ..      75     324 .. 0.87

  Alignments for each domain:
  == domain 1  score: 42.9 bits;  conditional E-value: 4e-15
  Terpene_synth_C  21 elsrWwkelglasklsfaRdrlvecyfwalgvvfepeysraRiilaKvivlitilDDtyDvyg........tleEleklteaierWdesaveel 106
                      e+ +W k ++  ++++ +++r   +y w +++++    ++  ++l +++  i + DD +D+ g        t++ +e+ + ++e +   + +  
       EEA21257.1  77 EIDEWLKTVKV-EEVKKIKHRARGNYTWLTATYYSDAPKEKLLLLSQFLYWIFFWDDEIDTGGqltqdrqgTVKCCEETNRCVEDCLGPNPNFT 169
                      7899*******.99999****************************************9998886666566588889999999999987555555 PP

  Terpene_synth_C 107 p.eymkilykallntfneledelekeeksdrvskylkeawkelvkaylkeakWreekyvPsfeEylenslvssglpllllaa.lvgmgdevtke 198
                      p    +   ++++ +++++ +++ +     ++ + l+++++++++ + +e   r+++ +P+  E  ++    +g+ + ++   +  m+     e
       EEA21257.1 170 PpPGSRPTVEMFYPILTQFRQSMGA----VSI-ERLRKELHDYINGVSREQVVRQKETLPTPAELFKMRCDDVGVIPSITQNeY-AMDF----E 253
                      42788****************9998....346.689999***********************************9999999945.7764....5 PP

  Terpene_synth_C 199 afewvasypklvkalstilRL...lnDiasyereqkrgdvassvecymkehgvseeeAveeikklied 263
                        +w+++++ + +++++++RL   +nDi s ++e   g++ ++v +ym + g + eeA + + +li++
       EEA21257.1 254 LPQWIHEHEAMQEVIKEVTRLtilINDILSLQKEFRVGQLENMVILYMYHEGLTLEEALDVMLDLIRE 321
                      6678888888888888888853337************99**********************9999987 PP

>> TRI5  Trichodiene synthase (TRI5)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0      0.36   3.3e+03      70     103 ..     103     136 ..      84     139 .. 0.74
   2 ?   12.9   0.1   4.1e-06     0.037     206     291 ..     262     350 ..     196     382 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 0.36
        TRI5  70 llvvycwakvpkevmvdvsiylayilvlddssde 103
                  l+   ++  pke +  +s +l +i   dd+ d+
  EEA21257.1 103 WLTATYYSDAPKEKLLLLSQFLYWIFFWDDEIDT 136
                 4555567888999999999999999999998775 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 4.1e-06
        TRI5 206 aeissavaqienqlvlvndllsfykeydderdqinlvsnlvtvdgitldeale...kltddtihackql.vavlkdkdpkvlatirafvh 291
                 + +  ++ ++    +l+nd+ls+ ke+   +   n+v  ++  +g+tl+eal+    l ++    c+     + k  + k+ a +++++ 
  EEA21257.1 262 EAMQEVIKEVTRLTILINDILSLQKEFRVGQL-ENMVILYMYHEGLTLEEALDvmlDLIREHYVLCTAAeQRIPKTGNLKLDADVQTYIV 350
                 56778889999999*************96554.5899999***********982223344444333332133444444445555555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (388 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       688  (0.0383736); expected 358.6 (0.02)
Passed bias filter:                      525  (0.0292822); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.42
# Mc/sec: 2759.55
//
Query:       EEA21258.1  [L=513]
Description: cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-34  119.5   0.0    2.2e-34  119.0   0.0    1.1  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.0   0.0   1.2e-38   2.2e-34     110     448 ..     144     493 ..     131     509 .. 0.86

  Alignments for each domain:
  == domain 1  score: 119.0 bits;  conditional E-value: 1.2e-38
                 STT.THHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCCCH.HHTCCSCHHH CS
        p450 110 gkl.sleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelssllskssvqllllfp.llkylptkll 206
                 +kl +++  v+ e++ ++++  ++++  + +++ +ll ++   v+++i++g +++  + ++ ++l +++++ +++   + + +  + + +++yl+ + +
  EEA21258.1 144 QKLgQFVTDVQNEVAHVIDATFPTCEDWTPVNLNNLLLRIISQVSARIFVGPSLN-RN-KEWLDLSEKFATDVMIGGEKLKGWRPILRpIAQYLIPEVR 240
                 577788888888888888888899998889**********************988.44.4444555555555555555555554444448999998888 PP

                 HHHHHHHHHHHHHHHHHHHHHHHCHCHC...SCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHH CS
        p450 207 rklkeavkklkdlldklieerretldsa...kksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklreE 302
                 r   ++ +++ ++l++++e r +   +     k+++d+l  +     +k+++++++ +e a+  l   +a+++Tt  ++  +L+ La +Pe+ + lreE
  EEA21258.1 241 RIQADH-EEAYQMLRPVLEARDRAEAELgyeYKKPNDMLEWIRTRA-TKNNDKSVDYREQANIQLLTATAAIHTTRLATLHVLFDLAARPEYIDPLREE 337
                 887766.9999********999888877888779*****9999996.8888889********************************************* PP

                 HHHHC.CTTTT-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEETT.EEE-TT-EEEEEHHHHHT-TTTSSSTTS--GGGGB-TTS...... CS
        p450 303 idevl.gdkreptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirg.ylipkGtevivnlyalhrdpevfpnPeeFdpeRFldekg...... 393
                 ++evl + +  +t + l++l+ ld + kE++R  p++  + +R+v+ ++++++   +p G +v+ n++ l   pe + +P+ Fd  RF + +       
  EEA21258.1 338 LREVLsETNGVLTKQTLTHLKKLDSFMKESQRHNPPSLATFQRKVLIPIKLSNgLELPVGVIVQCNTGVLDEVPESWGDPHAFDGFRFYRLRRkpedah 436
                 *****88888*****************************************999**********************************99998999999 PP

                 ..CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGEEES CS
        p450 394 ..nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdpppile 448
                   ++ + s +++ FG G+ +C+G+ +A+ ++k++la+l+ ++++ l + ++ +p++ 
  EEA21258.1 437 kyQFPSISLESMEFGLGKDACPGRFFATNQIKIILAHLIFHYDIALEKPEAGRPKNF 493
                 9999999************************************98866555555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (513 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       577  (0.0321825); expected 358.6 (0.02)
Passed bias filter:                      514  (0.0286686); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.27s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 3353.65
//
Query:       EEA21259.1  [L=409]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.9e-11   43.9   1.6    2.1e-11   43.7   0.1    1.7  2  Caps_synth      Capsular polysaccharide synthesis protein
    0.00037   21.1   0.1      0.001   19.7   0.0    1.8  2  Gly_transf_sug  Glycosyltransferase sugar-binding region cont
  ------ inclusion threshold ------
       0.18   11.1   0.2       0.65    9.2   0.0    1.9  2  TcdA_TcdB       TcdA/TcdB catalytic glycosyltransferase domai


Domain annotation for each model (and alignments):
>> Caps_synth  Capsular polysaccharide synthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.7   0.1   3.5e-15   2.1e-11      22     196 ..      18     205 ..      14     220 .. 0.78
   2 ?   -4.3   0.2       1.5   9.1e+03     240     271 ..     283     314 ..     271     325 .. 0.59

  Alignments for each domain:
  == domain 1  score: 43.7 bits;  conditional E-value: 3.5e-15
  Caps_synth  22 lkklkkklkkkleefdkkkkkeeenekkIWvlWlqGldna.PeiVkkciksvkknaedyevvlLtkd.....NieeYvdlpdfiieklekgki....sa 110
                 ++kl+++ ++++ +  k+ k+ ++++k++W +W  G+d++ P   ++ i+ v++  + + v +L+k       +++++   d++ e +++ ++      
  EEA21259.1  18 ESKLDQRCDDEIAAELKSYKEVTSSDKNVWAFWNTGFDTMhPWTQRNVINWVRRLGPSWMVRVLDKVpgspvHVSKFIPA-DNLPEAFNASTMtgpnVG 115
                 578999999999999999999999***************97888888888888888*********962222246666653.344566777777544345 PP

  Caps_synth 111 ahfSDllRleLLkkyGGvWiDaTifltkklpsell.....kkdfftfkssekksnkislssWtsfflaakknnpllsllkdllleYwkken 196
                  h  D++Rl LL  yGG W+D  + l + l+++        ++ + +     + n  +++   + f+aak++n +++ ++d++++ wk+ +
  EEA21259.1 116 PHSGDMVRLPLLYLYGGAWMDVGMMLFRHLDDTCWntiedSSNSYEMAGMSIEINPGATNML-NGFIAAKRGNGFIKRWHDIYMQIWKDGR 205
                 6889**********************999998876556443344444555556656655555.99**********************9765 PP

  == domain 2  score: -4.3 bits;  conditional E-value: 1.5
  Caps_synth 240 kekfdeelwkkikkqtslhKltykievkekkk 271
                  e+++ +l++  + ++++  l+ k+++k+++k
  EEA21259.1 283 TETWKFQLLTAWNGKKQFELLSTKKDIKDDSK 314
                 45555555555555666666666666665555 PP

>> Gly_transf_sug  Glycosyltransferase sugar-binding region containing DXD motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.0   1.7e-07     0.001      56      88 ..     114     150 ..      59     160 .. 0.80
   2 ?   -2.4   0.1       1.3   7.6e+03      30      52 ..     302     324 ..     281     337 .. 0.64

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 1.7e-07
  Gly_transf_sug  56 lfialsDllRlaiLykyGGiYlDtDvivlksl....r 88 
                     + +++ D++Rl +Ly yGG  +D+ +++ ++l     
      EEA21259.1 114 VGPHSGDMVRLPLLYLYGGAWMDVGMMLFRHLddtcW 150
                     467899*************************944433 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 1.3
  Gly_transf_sug  30 vrvaildlefllsdtpwfeeakk 52 
                      +  ++d+++ +++t+ ++ea++
      EEA21259.1 302 LLSTKKDIKDDSKKTELYDEANS 324
                     44455677777777777776666 PP

>> TcdA_TcdB  TcdA/TcdB catalytic glycosyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.0   0.00011      0.65     201     244 ..     119     165 ..     117     176 .. 0.81
   2 ?   -1.2   0.0      0.16   9.4e+02     104     133 ..     296     325 ..     270     366 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00011
                 HHHHHHHHHHHH-EEEE-TT-E..E-B-TTTTTTS---T.TS..-HH CS
   TcdA_TcdB 201 sDivRllvLkelGGlyldvDml..Psisqelfelikkssded.feda 244
                  D+vRl +L+ +GG ++dv m+    ++ +  ++i++ss++   +++
  EEA21259.1 119 GDMVRLPLLYLYGGAWMDVGMMlfRHLDDTCWNTIEDSSNSYeMAGM 165
                 59*******************94457889999999999954434444 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.16
                 HHHHHHHHHTTSTT-HHHHHHHHHHHS--- CS
   TcdA_TcdB 104 afinflkakgnkntkDeirkeyLekeysld 133
                 +  +f ++  +k +kD+ +k+ L  e +  
  EEA21259.1 296 GKKQFELLSTKKDIKDDSKKTELYDEANSF 325
                 445566666777899999999999887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (409 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       452  (0.0252106); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.49
# Mc/sec: 2491.43
//
Query:       EEA21260.1  [L=317]
Description: ribose-phosphate pyrophosphokinase 1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.1e-42  144.0   1.5    1.5e-36  126.1   0.2    2.7  3  Pribosyl_synth  Phosphoribosyl synthetase-associated domain
    9.9e-42  141.6   0.0    2.4e-41  140.3   0.0    1.7  2  Pribosyltran_N  N-terminal domain of ribose phosphate pyropho
    7.7e-13   48.3   0.2    1.7e-12   47.2   0.2    1.5  1  Pribosyltran    Phosphoribosyl transferase domain
     0.0049   16.3   0.1     0.0077   15.7   0.1    1.3  1  UPRTase         Uracil phosphoribosyltransferase


Domain annotation for each model (and alignments):
>> Pribosyl_synth  Phosphoribosyl synthetase-associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0      0.78   3.5e+03     103     121 ..     114     132 ..     108     136 .. 0.85
   2 !   16.3   0.0   1.7e-06    0.0077       3      36 ..     163     196 ..     161     202 .. 0.92
   3 !  126.1   0.2   3.4e-40   1.5e-36      75     183 ..     205     313 ..     197     314 .. 0.98

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.78
                     HHHHHHTT--EEEEEEEEE CS
  Pribosyl_synth 103 aevlkerGaykiyvlathG 121
                     a++l+  Ga  ++ +  h 
      EEA21260.1 114 ANMLQSAGATHVITMDLHA 132
                     8999999**9999998885 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 1.7e-06
                     GGEEEEESSGGGHHHHHHHHHHTT-EEEEE---- CS
  Pribosyl_synth   3 rnavivakspgsakkatsyaerlrlglavihGeq 36 
                      n+viv+ + g ak+  s a+rl +g a+ih e+
      EEA21260.1 163 DNCVIVSPDAGGAKRVVSLADRLGVGFALIHKER 196
                     699****************************996 PP

  == domain 3  score: 126.1 bits;  conditional E-value: 3.4e-40
                     --EES--TTSEEEEEEEEE-S-HHHHHHHHHHHHTT--EEEEEEEEE---TTHHHHHHHSS--EEEEESSS--HHHHHT-TTEEEE--HHHHHHH CS
  Pribosyl_synth  75 ltvvGdvgGriaiivddliddvesfvaaaevlkerGaykiyvlathGllssdaprlleesaidevvvtntipheiqklrcskiktvdislllaea 169
                     + +vGdv+ r ai++dd+ d   ++ +aa +l+e+Ga  +y+++thG+ls  a +++++s++  +vvtntip   + +rc kik +d+s +laea
      EEA21260.1 205 MILVGDVSNRTAILIDDMADTCGTLAKAASTLEEHGARDVYAIVTHGVLSGPAIETINNSCLSGLVVTNTIPLGDKIARCPKIKVIDVSRILAEA 299
                     789******************************************************************************************** PP

                     HHHHHHT---TT-S CS
  Pribosyl_synth 170 irrihngesmsylf 183
                     irr hnges+sylf
      EEA21260.1 300 IRRTHNGESVSYLF 313
                     *************9 PP

>> Pribosyltran_N  N-terminal domain of ribose phosphate pyrophosphokinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.3   0.0   5.4e-45   2.4e-41       1     116 []       4     121 ..       4     121 .. 0.98
   2 ?   -3.4   0.0       2.1   9.2e+03      68      86 ..     230     248 ..     214     250 .. 0.69

  Alignments for each domain:
  == domain 1  score: 140.3 bits;  conditional E-value: 5.4e-45
  Pribosyltran_N   1 lkifagssskeLaekiakrlgvelgkakvsrfadgEikveieesvrgkdvfiiqsls.kpvndnlmelllmidalrrasakritaViPylgysrq 94 
                     +k+++g+s+++L++++a+rlg++l+++ ++  + gEi+v+i esvrg+dv+i+qs++  +vnd lmell +i+a+r+asa++itaViP ++y+rq
      EEA21260.1   4 IKLISGTSHPDLSARVADRLGISLINTLCQPSSIGEISVSIGESVRGDDVYILQSTApGSVNDGLMELLNLIHACRTASARSITAVIPNYPYARQ 98 
                     699*****************************************************9789*********************************** PP

  Pribosyltran_N  95 drk.ksrepisaklvaklLeaaG 116
                     d+k ksr+pisa+lva++L++aG
      EEA21260.1  99 DKKdKSRAPISARLVANMLQSAG 121
                     ***999***************99 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 2.1
  Pribosyltran_N  68 llmidalrrasakritaVi 86 
                        +++l++  a+ + a++
      EEA21260.1 230 AKAASTLEEHGARDVYAIV 248
                     4556777777777777776 PP

>> Pribosyltran  Phosphoribosyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.2   0.2   3.8e-16   1.7e-12      30     124 ..     164     250 ..     152     266 .. 0.92

  Alignments for each domain:
  == domain 1  score: 47.2 bits;  conditional E-value: 3.8e-16
                   GEEEEEEETTTHHHHHHHHHHSTT-EE-EEEEEE-TTT--EE........EE----TTSEEEEE-SEESSSHHHHHHHHHHHCC-BSEEEEEEEE CS
  Pribosyltran  30 pdvvvgiargGvpfakiladeLevplayvrkvkyrpdgseeaargssdesrlledpagkkVliVDDildtGgTllaalelLkekgpeevriavlv 124
                   + v+v ++ gG  ++  lad+L+v +a + k++ rp++ + ++        l +d+ +++ +++DD+ dt gTl +a+  L+e+g+  v ++v +
    EEA21260.1 164 NCVIVSPDAGGAKRVVSLADRLGVGFALIHKERPRPNVVGRMI--------LVGDVSNRTAILIDDMADTCGTLAKAASTLEEHGARDVYAIVTH 250
                   66****************************************9........9**********************************999888865 PP

>> UPRTase  Uracil phosphoribosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.1   1.7e-06    0.0077     115     172 ..     207     264 ..     175     277 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 1.7e-06
     UPRTase 115 LPkkiaertvlllDpviaTGgsaaaaiqlLkergvgeekIlvlsvlaseegvkrlaee 172
                 L  ++++rt++l+D +  T g++a+a ++L e+g++    +v   + s  +++++ ++
  EEA21260.1 207 LVGDVSNRTAILIDDMADTCGTLAKAASTLEEHGARDVYAIVTHGVLSGPAIETINNS 264
                 5568899***************************987777777777777777776665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (317 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       415  (0.0231469); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2154.17
//
Query:       EEA21261.1  [L=264]
Description: ribose-phosphate pyrophosphokinase 1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.8e-42  145.5   0.9      1e-36  126.7   0.2    2.6  3  Pribosyl_synth  Phosphoribosyl synthetase-associated domain
    6.6e-13   48.5   0.2    1.2e-12   47.7   0.2    1.4  1  Pribosyltran    Phosphoribosyl transferase domain
      0.003   17.1   0.0     0.0053   16.2   0.0    1.4  1  UPRTase         Uracil phosphoribosyltransferase
  ------ inclusion threshold ------
      0.032   14.2   0.1      0.099   12.6   0.0    1.9  2  Pribosyltran_N  N-terminal domain of ribose phosphate pyropho


Domain annotation for each model (and alignments):
>> Pribosyl_synth  Phosphoribosyl synthetase-associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0      0.51   2.3e+03     102     121 ..      60      79 ..      47      83 .. 0.84
   2 !   16.6   0.0   1.4e-06    0.0061       3      36 ..     110     143 ..     108     148 .. 0.92
   3 !  126.7   0.2   2.3e-40     1e-36      75     183 ..     152     260 ..     144     261 .. 0.98

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.51
                     HHHHHHHTT--EEEEEEEEE CS
  Pribosyl_synth 102 aaevlkerGaykiyvlathG 121
                      a++l+  Ga  ++ +  h 
      EEA21261.1  60 VANMLQSAGATHVITMDLHA 79 
                     48999999999999998875 PP

  == domain 2  score: 16.6 bits;  conditional E-value: 1.4e-06
                     GGEEEEESSGGGHHHHHHHHHHTT-EEEEE---- CS
  Pribosyl_synth   3 rnavivakspgsakkatsyaerlrlglavihGeq 36 
                      n+viv+ + g ak+  s a+rl +g a+ih e+
      EEA21261.1 110 DNCVIVSPDAGGAKRVVSLADRLGVGFALIHKER 143
                     699****************************996 PP

  == domain 3  score: 126.7 bits;  conditional E-value: 2.3e-40
                     --EES--TTSEEEEEEEEE-S-HHHHHHHHHHHHTT--EEEEEEEEE---TTHHHHHHHSS--EEEEESSS--HHHHHT-TTEEEE--HHHHHHH CS
  Pribosyl_synth  75 ltvvGdvgGriaiivddliddvesfvaaaevlkerGaykiyvlathGllssdaprlleesaidevvvtntipheiqklrcskiktvdislllaea 169
                     + +vGdv+ r ai++dd+ d   ++ +aa +l+e+Ga  +y+++thG+ls  a +++++s++  +vvtntip   + +rc kik +d+s +laea
      EEA21261.1 152 MILVGDVSNRTAILIDDMADTCGTLAKAASTLEEHGARDVYAIVTHGVLSGPAIETINNSCLSGLVVTNTIPLGDKIARCPKIKVIDVSRILAEA 246
                     789******************************************************************************************** PP

                     HHHHHHT---TT-S CS
  Pribosyl_synth 170 irrihngesmsylf 183
                     irr hnges+sylf
      EEA21261.1 247 IRRTHNGESVSYLF 260
                     *************9 PP

>> Pribosyltran  Phosphoribosyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.7   0.2   2.6e-16   1.2e-12      30     124 ..     111     197 ..      99     213 .. 0.92

  Alignments for each domain:
  == domain 1  score: 47.7 bits;  conditional E-value: 2.6e-16
                   GEEEEEEETTTHHHHHHHHHHSTT-EE-EEEEEE-TTT--EE........EE----TTSEEEEE-SEESSSHHHHHHHHHHHCC-BSEEEEEEEE CS
  Pribosyltran  30 pdvvvgiargGvpfakiladeLevplayvrkvkyrpdgseeaargssdesrlledpagkkVliVDDildtGgTllaalelLkekgpeevriavlv 124
                   + v+v ++ gG  ++  lad+L+v +a + k++ rp++ + ++        l +d+ +++ +++DD+ dt gTl +a+  L+e+g+  v ++v +
    EEA21261.1 111 NCVIVSPDAGGAKRVVSLADRLGVGFALIHKERPRPNVVGRMI--------LVGDVSNRTAILIDDMADTCGTLAKAASTLEEHGARDVYAIVTH 197
                   66****************************************9........9**********************************999888865 PP

>> UPRTase  Uracil phosphoribosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   1.2e-06    0.0053     115     172 ..     154     211 ..     122     225 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.2e-06
     UPRTase 115 LPkkiaertvlllDpviaTGgsaaaaiqlLkergvgeekIlvlsvlaseegvkrlaee 172
                 L  ++++rt++l+D +  T g++a+a ++L e+g++    +v   + s  +++++ ++
  EEA21261.1 154 LVGDVSNRTAILIDDMADTCGTLAKAASTLEEHGARDVYAIVTHGVLSGPAIETINNS 211
                 5568899***************************987777777777777777777665 PP

>> Pribosyltran_N  N-terminal domain of ribose phosphate pyrophosphokinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   2.2e-05     0.099      98     116 .]      50      68 ..      32      68 .. 0.91
   2 ?   -2.9   0.0       1.4   6.4e+03      67      86 ..     176     195 ..     157     197 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 2.2e-05
  Pribosyltran_N  98 ksrepisaklvaklLeaaG 116
                     ksr+pisa+lva++L++aG
      EEA21261.1  50 KSRAPISARLVANMLQSAG 68 
                     78***************99 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.4
  Pribosyltran_N  67 lllmidalrrasakritaVi 86 
                     l   +++l++  a+ + a++
      EEA21261.1 176 LAKAASTLEEHGARDVYAIV 195
                     45556777777777777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (264 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       540  (0.0301188); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1791.37
//
Query:       EEA21262.1  [L=290]
Description: ribose-phosphate pyrophosphokinase 1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.1e-42  142.2   0.1      2e-41  140.6   0.0    1.8  2  Pribosyltran_N  N-terminal domain of ribose phosphate pyropho
    2.1e-26   93.1   1.8    6.6e-21   75.2   0.3    2.7  3  Pribosyl_synth  Phosphoribosyl synthetase-associated domain
    6.5e-13   48.5   0.2    1.3e-12   47.5   0.2    1.5  1  Pribosyltran    Phosphoribosyl transferase domain
     0.0036   16.8   0.0     0.0055   16.2   0.0    1.3  1  UPRTase         Uracil phosphoribosyltransferase


Domain annotation for each model (and alignments):
>> Pribosyltran_N  N-terminal domain of ribose phosphate pyrophosphokinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.6   0.0   4.4e-45     2e-41       1     116 []       4     121 ..       4     121 .. 0.98
   2 ?   -1.2   0.0      0.41   1.8e+03      47      82 ..     241     283 ..     216     288 .. 0.66

  Alignments for each domain:
  == domain 1  score: 140.6 bits;  conditional E-value: 4.4e-45
  Pribosyltran_N   1 lkifagssskeLaekiakrlgvelgkakvsrfadgEikveieesvrgkdvfiiqsls.kpvndnlmelllmidalrrasakritaViPylgysrq 94 
                     +k+++g+s+++L++++a+rlg++l+++ ++  + gEi+v+i esvrg+dv+i+qs++  +vnd lmell +i+a+r+asa++itaViP ++y+rq
      EEA21262.1   4 IKLISGTSHPDLSARVADRLGISLINTLCQPSSIGEISVSIGESVRGDDVYILQSTApGSVNDGLMELLNLIHACRTASARSITAVIPNYPYARQ 98 
                     699*****************************************************9789*********************************** PP

  Pribosyltran_N  95 drk.ksrepisaklvaklLeaaG 116
                     d+k ksr+pisa+lva++L++aG
      EEA21262.1  99 DKKdKSRAPISARLVANMLQSAG 121
                     ***999***************99 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.41
  Pribosyltran_N  47 gkdvfiiqsls.......kpvndnlmelllmidalrrasakri 82 
                      +dv+ i+++        + +n++ +  l++++++ r+  ++i
      EEA21262.1 241 ARDVYAIVTHGvlsgpaiETINNSCLSGLVVTNTIPRKDSRSI 283
                     4566666666566666666666666666666666666666666 PP

>> Pribosyl_synth  Phosphoribosyl synthetase-associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0      0.69   3.1e+03     103     121 ..     114     132 ..     108     136 .. 0.85
   2 !   16.5   0.0   1.4e-06    0.0064       3      36 ..     163     196 ..     161     204 .. 0.92
   3 !   75.2   0.3   1.5e-24   6.6e-21      75     149 ..     205     279 ..     197     289 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.69
                     HHHHHHTT--EEEEEEEEE CS
  Pribosyl_synth 103 aevlkerGaykiyvlathG 121
                     a++l+  Ga  ++ +  h 
      EEA21262.1 114 ANMLQSAGATHVITMDLHA 132
                     8999999**9999998885 PP

  == domain 2  score: 16.5 bits;  conditional E-value: 1.4e-06
                     GGEEEEESSGGGHHHHHHHHHHTT-EEEEE---- CS
  Pribosyl_synth   3 rnavivakspgsakkatsyaerlrlglavihGeq 36 
                      n+viv+ + g ak+  s a+rl +g a+ih e+
      EEA21262.1 163 DNCVIVSPDAGGAKRVVSLADRLGVGFALIHKER 196
                     699****************************996 PP

  == domain 3  score: 75.2 bits;  conditional E-value: 1.5e-24
                     --EES--TTSEEEEEEEEE-S-HHHHHHHHHHHHTT--EEEEEEEEE---TTHHHHHHHSS--EEEEESSS--HH CS
  Pribosyl_synth  75 ltvvGdvgGriaiivddliddvesfvaaaevlkerGaykiyvlathGllssdaprlleesaidevvvtntiphei 149
                     + +vGdv+ r ai++dd+ d   ++ +aa +l+e+Ga  +y+++thG+ls  a +++++s++  +vvtntip++ 
      EEA21262.1 205 MILVGDVSNRTAILIDDMADTCGTLAKAASTLEEHGARDVYAIVTHGVLSGPAIETINNSCLSGLVVTNTIPRKD 279
                     789*********************************************************************853 PP

>> Pribosyltran  Phosphoribosyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.5   0.2   2.9e-16   1.3e-12      30     124 ..     164     250 ..     152     269 .. 0.92

  Alignments for each domain:
  == domain 1  score: 47.5 bits;  conditional E-value: 2.9e-16
                   GEEEEEEETTTHHHHHHHHHHSTT-EE-EEEEEE-TTT--EE........EE----TTSEEEEE-SEESSSHHHHHHHHHHHCC-BSEEEEEEEE CS
  Pribosyltran  30 pdvvvgiargGvpfakiladeLevplayvrkvkyrpdgseeaargssdesrlledpagkkVliVDDildtGgTllaalelLkekgpeevriavlv 124
                   + v+v ++ gG  ++  lad+L+v +a + k++ rp++ + ++        l +d+ +++ +++DD+ dt gTl +a+  L+e+g+  v ++v +
    EEA21262.1 164 NCVIVSPDAGGAKRVVSLADRLGVGFALIHKERPRPNVVGRMI--------LVGDVSNRTAILIDDMADTCGTLAKAASTLEEHGARDVYAIVTH 250
                   66****************************************9........9**********************************999888876 PP

>> UPRTase  Uracil phosphoribosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   1.2e-06    0.0055     115     174 ..     207     266 ..     175     281 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.2e-06
     UPRTase 115 LPkkiaertvlllDpviaTGgsaaaaiqlLkergvgeekIlvlsvlaseegvkrlaeefp 174
                 L  ++++rt++l+D +  T g++a+a ++L e+g++    +v   + s  +++++ ++  
  EEA21262.1 207 LVGDVSNRTAILIDDMADTCGTLAKAASTLEEHGARDVYAIVTHGVLSGPAIETINNSCL 266
                 5568899***************************98877777777777777777766655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (290 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       330  (0.0184059); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2197.81
//
Query:       EEA21263.1  [L=323]
Description: ribose-phosphate pyrophosphokinase 1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-41  141.5   0.0    2.5e-41  140.2   0.0    1.7  2  Pribosyltran_N  N-terminal domain of ribose phosphate pyropho
    3.4e-32  112.0   4.0    3.5e-27   95.6   1.2    2.7  3  Pribosyl_synth  Phosphoribosyl synthetase-associated domain
    8.3e-13   48.2   0.2    1.8e-12   47.1   0.2    1.5  1  Pribosyltran    Phosphoribosyl transferase domain
      0.005   16.3   0.1      0.008   15.6   0.1    1.3  1  UPRTase         Uracil phosphoribosyltransferase


Domain annotation for each model (and alignments):
>> Pribosyltran_N  N-terminal domain of ribose phosphate pyrophosphokinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.2   0.0   5.6e-45   2.5e-41       1     116 []       4     121 ..       4     121 .. 0.98
   2 ?   -3.5   0.0       2.2   9.7e+03      68      86 ..     230     248 ..     215     250 .. 0.69

  Alignments for each domain:
  == domain 1  score: 140.2 bits;  conditional E-value: 5.6e-45
  Pribosyltran_N   1 lkifagssskeLaekiakrlgvelgkakvsrfadgEikveieesvrgkdvfiiqsls.kpvndnlmelllmidalrrasakritaViPylgysrq 94 
                     +k+++g+s+++L++++a+rlg++l+++ ++  + gEi+v+i esvrg+dv+i+qs++  +vnd lmell +i+a+r+asa++itaViP ++y+rq
      EEA21263.1   4 IKLISGTSHPDLSARVADRLGISLINTLCQPSSIGEISVSIGESVRGDDVYILQSTApGSVNDGLMELLNLIHACRTASARSITAVIPNYPYARQ 98 
                     699*****************************************************9789*********************************** PP

  Pribosyltran_N  95 drk.ksrepisaklvaklLeaaG 116
                     d+k ksr+pisa+lva++L++aG
      EEA21263.1  99 DKKdKSRAPISARLVANMLQSAG 121
                     ***999***************99 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 2.2
  Pribosyltran_N  68 llmidalrrasakritaVi 86 
                        +++l++  a+ + a++
      EEA21263.1 230 AKAASTLEEHGARDVYAIV 248
                     4556777777788777776 PP

>> Pribosyl_synth  Phosphoribosyl synthetase-associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0      0.79   3.6e+03     103     121 ..     114     132 ..     108     136 .. 0.85
   2 !   16.3   0.0   1.7e-06    0.0075       3      36 ..     163     196 ..     161     204 .. 0.92
   3 !   95.6   1.2   7.8e-31   3.5e-27      75     169 ..     205     299 ..     196     307 .. 0.95

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 0.79
                     HHHHHHTT--EEEEEEEEE CS
  Pribosyl_synth 103 aevlkerGaykiyvlathG 121
                     a++l+  Ga  ++ +  h 
      EEA21263.1 114 ANMLQSAGATHVITMDLHA 132
                     8999999**9999998885 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 1.7e-06
                     GGEEEEESSGGGHHHHHHHHHHTT-EEEEE---- CS
  Pribosyl_synth   3 rnavivakspgsakkatsyaerlrlglavihGeq 36 
                      n+viv+ + g ak+  s a+rl +g a+ih e+
      EEA21263.1 163 DNCVIVSPDAGGAKRVVSLADRLGVGFALIHKER 196
                     699****************************996 PP

  == domain 3  score: 95.6 bits;  conditional E-value: 7.8e-31
                     --EES--TTSEEEEEEEEE-S-HHHHHHHHHHHHTT--EEEEEEEEE---TTHHHHHHHSS--EEEEESSS--HHHHHT-TTEEEE--HHHHHHH CS
  Pribosyl_synth  75 ltvvGdvgGriaiivddliddvesfvaaaevlkerGaykiyvlathGllssdaprlleesaidevvvtntipheiqklrcskiktvdislllaea 169
                     + +vGdv+ r ai++dd+ d   ++ +aa +l+e+Ga  +y+++thG+ls  a +++++s++  +vvtntip   + +rc kik +d+s +lae 
      EEA21263.1 205 MILVGDVSNRTAILIDDMADTCGTLAKAASTLEEHGARDVYAIVTHGVLSGPAIETINNSCLSGLVVTNTIPLGDKIARCPKIKVIDVSRILAEV 299
                     789******************************************************************************************96 PP

>> Pribosyltran  Phosphoribosyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.1   0.2   3.9e-16   1.8e-12      30     124 ..     164     250 ..     152     266 .. 0.92

  Alignments for each domain:
  == domain 1  score: 47.1 bits;  conditional E-value: 3.9e-16
                   GEEEEEEETTTHHHHHHHHHHSTT-EE-EEEEEE-TTT--EE........EE----TTSEEEEE-SEESSSHHHHHHHHHHHCC-BSEEEEEEEE CS
  Pribosyltran  30 pdvvvgiargGvpfakiladeLevplayvrkvkyrpdgseeaargssdesrlledpagkkVliVDDildtGgTllaalelLkekgpeevriavlv 124
                   + v+v ++ gG  ++  lad+L+v +a + k++ rp++ + ++        l +d+ +++ +++DD+ dt gTl +a+  L+e+g+  v ++v +
    EEA21263.1 164 NCVIVSPDAGGAKRVVSLADRLGVGFALIHKERPRPNVVGRMI--------LVGDVSNRTAILIDDMADTCGTLAKAASTLEEHGARDVYAIVTH 250
                   66****************************************9........9**********************************999888865 PP

>> UPRTase  Uracil phosphoribosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.1   1.8e-06     0.008     115     172 ..     207     264 ..     175     277 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 1.8e-06
     UPRTase 115 LPkkiaertvlllDpviaTGgsaaaaiqlLkergvgeekIlvlsvlaseegvkrlaee 172
                 L  ++++rt++l+D +  T g++a+a ++L e+g++    +v   + s  +++++ ++
  EEA21263.1 207 LVGDVSNRTAILIDDMADTCGTLAKAASTLEEHGARDVYAIVTHGVLSGPAIETINNS 264
                 5568899***************************987777777777777777776665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (323 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       449  (0.0250432); expected 358.6 (0.02)
Passed bias filter:                      386  (0.0215294); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.40
# Mc/sec: 2452.03
//
Query:       EEA21264.1  [L=389]
Description: glycosyl hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.5e-46  159.6   9.8    1.5e-46  159.6   9.8    1.5  2  Glyco_hydro_76  Glycosyl hydrolase family 76
    0.00011   21.4   0.6       0.14   11.2   0.0    3.1  3  Glyco_hydro_88  Glycosyl Hydrolase Family 88
  ------ inclusion threshold ------
      0.036   13.6   0.1       0.14   11.6   0.0    1.9  2  C5-epim_C       D-glucuronyl C5-epimerase C-terminus


Domain annotation for each model (and alignments):
>> Glyco_hydro_76  Glycosyl hydrolase family 76
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.6      0.62   3.7e+03      27      45 ..      42      59 ..      20      78 .. 0.54
   2 !  159.6   9.8   2.5e-50   1.5e-46      84     348 ..     133     383 ..     111     389 .] 0.86

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 0.62
                    CBSCES-GHHHHHHHHHHH CS
  Glyco_hydro_76 27 gnlpdpyywWeagalfgal 45
                    g +++   wW+ + +++ +
      EEA21264.1 42 GLWNTA-GWWNGANAMTVI 59
                    222222.566655555444 PP

  == domain 2  score: 159.6 bits;  conditional E-value: 2.5e-50
                     SEHHHHHHHHHHHHHHHHH.....H--HHHHHHHHHHHHHHHHCB-SCSCCS-BBSEC..ESS--SEEEHHHHHHHHHHHHHHHHHH..--CHHH CS
  Glyco_hydro_76  84 egnDDqafwglaamtaaernfpeptdepswLalAqavfntqasrwdeetcgGGlrWqiftwnsgydyknsisngplfqlaarLaryt..gnetYl 176
                       nDD  +wgla ++a+ +     t+++++L+lA+++fn +a+ w ++  +GG++W++      ++y n+i+   +  laa La     + +tY+
      EEA21264.1 133 RANDDAEWWGLAWVAAYDV-----TGNETYLTLAEGIFNKIAAGWGTNCENGGIYWET-----TNHYVNAIASELFISLAAHLANRVldNSATYI 217
                     58****************8.....9**********************989******86.....889******************876656677** PP

                     HHHHHHHHHHHHHSCSBTTTS-B-SEEETTTCCEEEE---HHHHHHHHHHHHHHHHHHH--HHHHHHHHHHHHHHHHHCEECTTEEEEEE-TTST CS
  Glyco_hydro_76 177 ewAekvwdWvedvgliddedwlvyDgasvednctdinklqwtYnqGtylsgaaylynaTgdekWldrvkgllnatlstffpdgnilyevacepse 271
                      wAe+ w+W +++g+i + +++++Dg+  +++c + ++  w+YnqG++l+g + l +++ +e++ d ++ +++a+ + + +++ +++++acep+ 
      EEA21264.1 218 AWAEEAWNWFANTGMI-NANGTINDGL--TSDCVNNGQPVWSYNQGVILGGLTELNRISPNESYIDSANSIAQAAIAAIADSNYVIHDYACEPN- 308
                     ****************.*********8..889*9999999***************************************************994. PP

                     TCCTTHHHHHHHHHHHHHHHH..SH.HHHHHHHHHHHHHHHHHHTTTB...TTTSB-TTTTT...SSCCHHHHHHHHCCHH CS
  Glyco_hydro_76 272 kcnnDqrsFkgilarwlaltaqlap.etadtiepllrasaeaaakscsggsdgttcglkwlk...gtwdgdaglgeqmsal 348
                      c+ D ++Fkgi++r l l+++  p +    + +++++ ae ++++ +++++g+ +g++w+    +  d ++ + ++m al
      EEA21264.1 309 -CEPDATQFKGIFMRNLLLLQKASPhDL---YSQVIKSCAESIWANDRDTTTGQ-LGVNWAGpfvTPADAST-VSSAMGAL 383
                     .9***************9*999999555...56667777777887776654444.99999953333344444.45555444 PP

>> Glyco_hydro_88  Glycosyl Hydrolase Family 88
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.1      0.02   1.2e+02      37      62 ..     144     169 ..     129     180 .. 0.81
   2 !    5.6   0.0    0.0012       7.3     249     305 ..     187     242 ..     181     251 .. 0.82
   3 !   11.2   0.0   2.4e-05      0.14      21      67 ..     249     295 ..     240     359 .. 0.71

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.02
                     HHHHHHHHH--HHHHHHHHHHHHHCC CS
  Glyco_hydro_88  37 glleayeatgdkeyldyakawadsli 62 
                     + ++ay+ tg+++yl +a+ ++++  
      EEA21264.1 144 AWVAAYDVTGNETYLTLAEGIFNKIA 169
                     34599*************99998765 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0012
                     TSSBEHHHHHHHHHHHHHHHHTTSS-.HHHHHHHHHHHHHHHHHC.EE-TTS-EEE-SE CS
  Glyco_hydro_88 249 esylEtSatalfvygLakgvnkglld.kkkykkvaqkawkallkk.aveedGqllvkqv 305
                     + y  ++a+ lf+ + a+ + +++ld ++ y   a++aw+ ++++  ++ +G+  ++++
      EEA21264.1 187 NHYVNAIASELFISLAAH-LANRVLDnSATYIAWAEEAWNWFANTgMINANGT--INDG 242
                     67999********99999.77777763688***************99999998..6655 PP

  == domain 3  score: 11.2 bits;  conditional E-value: 2.4e-05
                     SSTTCCE.HHHHHHHHHHHHHHHHH--HHHHHHHHHHHHHCCCTTS- CS
  Glyco_hydro_88  21 lkkenewewtnGvflsglleayeatgdkeyldyakawadslideggk 67 
                     ++ +  w +++Gv+l+gl e+  ++ ++ y+d a+++a+  i   + 
      EEA21264.1 249 NNGQPVWSYNQGVILGGLTELNRISPNESYIDSANSIAQAAIAAIAD 295
                     466789******************************99988877666 PP

>> C5-epim_C  D-glucuronyl C5-epimerase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   2.4e-05      0.14      38      77 ..     145     188 ..     138     207 .. 0.80
   2 ?   -2.1   0.0      0.37   2.2e+03      30      61 ..     258     289 ..     251     295 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 2.4e-05
   C5-epim_C  38 llrAYeltgdekYlkaakkalksfk....ipvekGGvlktledk 77 
                 +++AY++tg+e Yl++a+   + ++    ++ e+GG+ +++ ++
  EEA21264.1 145 WVAAYDVTGNETYLTLAEGIFNKIAagwgTNCENGGIYWETTNH 188
                 689**************988877652222789999999999884 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.37
   C5-epim_C  30 aqgqaisvllrAYeltgdekYlkaakkalksf 61 
                  qg ++  l++  + + +e+Y+++a+   +++
  EEA21264.1 258 NQGVILGGLTELNRISPNESYIDSANSIAQAA 289
                 57777777777778888999999999877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (389 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       470  (0.0262145); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.44
# Mc/sec: 2640.01
//
Query:       EEA21265.1  [L=580]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.6e-14   53.7   0.5      1e-13   51.1   0.0    2.5  2  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
    7.8e-14   51.7   0.1    2.8e-13   49.9   0.0    2.0  2  DDE_1        DDE superfamily endonuclease


Domain annotation for each model (and alignments):
>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.1   0.0   1.1e-17     1e-13       2      63 ..      64     125 ..      63     128 .. 0.93
   2 ?   -0.9   0.2      0.19   1.7e+03      27      56 ..     230     265 ..     225     268 .. 0.52

  Alignments for each domain:
  == domain 1  score: 51.1 bits;  conditional E-value: 1.1e-17
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHTS-- CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRhglk 63 
                  +++E a++ Wi +l+ rg+p+t ++ir++A++++++ + +   ++k++ +W++rF+kR++++
   EEA21265.1  64 DDQESAIIIWIDDLDDRGRPPTVHMIRNYAENVLQNMHPNAANPPKLGDRWVHRFLKRLPPA 125
                  79********************************88899999****************9875 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.19
                  HHHHHHHHH......HHSSSCT-TT-S--CHHHHHH CS
  HTH_Tnp_Tc5  27 irekAqela......slaadlgepdfkaSkgWldrF 56 
                  i e + +++      +++++ g ++    ++Wl++F
   EEA21265.1 230 ILESWFQYLtedewkVTITESGFSNDEIAYEWLQHF 265
                  444454544444444444444555555555666666 PP

>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.9   0.0   3.2e-17   2.8e-13       4     135 ..     205     337 ..     202     353 .. 0.88
   2 ?   -2.3   0.1      0.34   3.1e+03     107     145 ..     449     475 ..     430     513 .. 0.47

  Alignments for each domain:
  == domain 1  score: 49.9 bits;  conditional E-value: 3.2e-17
       DDE_1   4 ltvllcanaagsekLkplvigkaksprafkngektkkkldveyksnrkawltssifeeWLkvfdkrle..aekrkilLlldssrshetvel.leselqn 99 
                 l+++++ + a +  ++p +i+ +k + ++++  +   + +++ ++++ +   ++i  eWL++fd+ ++  a ++  lL +ds+++h t e+   + +++
  EEA21265.1 205 LVTVIEGINAAGSAIPPFLIFTGKVILESWF--QYLTEDEWKVTITESGFSNDEIAYEWLQHFDQHTReqAGNNWRLLTMDSHTAHLTREFmDYCLEHK 301
                 45556666666678*****************..66677789999************************98889999***************99999*** PP

       DDE_1 100 iklvflPassasllqPldqgvvselKarYrrqllqa 135
                 i  + +Pa++++llqPld   + + K+  rr+++++
  EEA21265.1 302 IVPFRFPAHTTHLLQPLDGMPFLHYKRIHRRAINEQ 337
                 ******************988888888888877665 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 0.34
       DDE_1 107 assasllqPldqgvvselKarYrrqllqalleeqnrlsk 145
                     sl + +d +              qa ++eq++ + 
  EEA21265.1 449 GIRRSLKKIFDGSL------------TQAHIKEQQQEQI 475
                 44444444444444............4444433333222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (580 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1317  (0.0734564); expected 358.6 (0.02)
Passed bias filter:                      680  (0.0379274); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.68u 0.31s 00:00:00.99 Elapsed: 00:00:00.47
# Mc/sec: 3708.05
//
Query:       EEA21266.1  [L=342]
Description: hypothetical protein PMAA_050810 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.2e-16   59.8   0.0    3.1e-09   36.2   0.0    2.9  3  COesterase  Carboxylesterase family


Domain annotation for each model (and alignments):
>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2   0.0   1.7e-13   3.1e-09     158     192 ..     134     168 ..     127     170 .. 0.94
   2 !   18.4   0.0   4.5e-08   0.00081     280     366 ..     180     269 ..     173     284 .. 0.74
   3 !    1.6   0.0    0.0056     1e+02     451     474 ..     283     307 ..     275     341 .. 0.74

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 1.7e-13
                 BS-HHHHHHHHHHHHHHHHGGGGTEEEEEEEEEEE CS
  COesterase 158 pGNvGllDqvlALrWVkenIasFGGdpervtlfGe 192
                 + N +l+Dq++ L+WVk+nI +FG d +r+t++G+
  EEA21266.1 134 TSNSALYDQRAGLDWVKRNIDHFGCDAKRITVMGD 168
                 67********************************7 PP

  == domain 2  score: 18.4 bits;  conditional E-value: 4.5e-08
                 C-SSS-B--SSSSSS-HHHHHHCGC....CSEEEEEEETTTTHHHHCCHSTTTSSSSHHHHHHHHHHHHHHHHHHHCC..HHHHHHHHHHHHS CS
  COesterase 280 lvsfaPvvdgdflpekPeellkseg....kvplliGvnkdegllflaylldkeksvkkkeeklsesllkdelyleaek..keelseaikeeyt 366
                  +++ P vdg ++p kP+ l+ +++    +v++++G n++eg+  ++  + ++ + +++++++++ +  + ly +  k  ++ l+e +++ y+
  EEA21266.1 180 TMTWTPAVDGVYVP-KPAGLMLKQAlfdhSVKIMTGHNSNEGTEAAYLAYLQQLIPDATNSTIDHVI--TVLYARVFKggQQYLTEGAQDIYL 269
                 689***********.88877777578********************999999877777777765443..444444444445555555555555 PP

  == domain 3  score: 1.6 bits;  conditional E-value: 0.0056
                 H.HHHHHHHHHHHHHHHHHHSSTTS CS
  COesterase 451 e.deklsrkmmtywtnFaktgnPnk 474
                 e   +l+++m +++t+F ktg   +
  EEA21266.1 283 EvNVTLAKQMQRLFTKFTKTGSLDG 307
                 447789**************96555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       337  (0.0187964); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.31s 00:00:00.81 Elapsed: 00:00:00.47
# Mc/sec: 2174.99
//
Query:       EEA21267.1  [L=554]
Description: general amino-acid permease GAP1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   2.8e-137  458.2  38.4   3.4e-137  457.9  38.4    1.0  1  AA_permease    Amino acid permease
    1.7e-36  126.0  41.8    2.2e-36  125.6  41.8    1.0  1  AA_permease_2  Amino acid permease
  ------ inclusion threshold ------
       0.08   11.7   0.1       0.15   10.8   0.1    1.4  1  DUF4781        Domain of unknown function (DUF4781)


Domain annotation for each model (and alignments):
>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  457.9  38.4  5.8e-141  3.4e-137       1     470 [.      45     492 ..      45     499 .. 0.98

  Alignments for each domain:
  == domain 1  score: 457.9 bits;  conditional E-value: 5.8e-141
  AA_permease   1 hvlvialggviGtglfvglgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgpelGfviGlnylfswitvlaleltaas 98 
                  h+++ia+gg+iG+g+fv++g +l+++Gp+++ll+y+ +g++++ +m +lge+a+++p++g++y y+ rf++p++Gf++G+ y ++w++ l++eltaa+
   EEA21267.1  45 HMQMIAIGGAIGAGFFVSTGGALRTGGPGALLLCYVTVGIMLLQTMWALGELAVMYPVNGAYYDYSLRFIDPSWGFAMGWDYAINWLVILPFELTAAG 142
                  99************************************************************************************************ PP

  AA_permease  99 iliqfwelvtdlpkawvtgavflvvlliinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkga.gfrflgdngsifknnlppgfakeee 195
                  i+i +w   +dl+   +++avflv+l++i+++gv++yge+ef+l++iki a+i+fii+gi++ +gg+p  g+ g+r+++d+g+      + +      
   EEA21267.1 143 ITIRYW--REDLN-VGIWIAVFLVILSAIQIFGVRGYGEVEFVLSIIKITAVIGFIILGIVIDCGGAPVGGYiGGRYWYDPGA------FTD------ 225
                  ******..*****.*********************************************************************......556...... PP

  AA_permease 196 gafknfisvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasa..aspfvifikesgvsvlapl 291
                    f +f+svf +++faf G+e+ +++a+E+++P+ksiPka +qv++rit+fYv ++l++gl+vp n++ l+n+s      spfv+ ik++g+++l+++
   EEA21267.1 226 --FVGFCSVFTTAAFAFGGTEMSGLAAAETANPAKSIPKACKQVFWRITVFYVVGTLIVGLIVPHNADYLMNASGANtsFSPFVVSIKNAGINGLPSV 321
                  ..79********************************************************************6654488******************* PP

  AA_permease 292 inaviltaalssansslysasRvlyslakdglaPkvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliilsylr 389
                  +navi ++++s+ans+++ ++R+++++a+ g+aPk++++v+k+g+P+  i+l +++++la++++++n++  ++f++lla+s++++++vw++++l+++r
   EEA21267.1 322 MNAVITISVISVANSATFGSTRTIQAMAEKGMAPKFFSYVDKHGRPIWCIVLQIAFGFLAFINEASNTG-GQIFTWLLALSGISNFFVWGSVCLAHIR 418
                  *********************************************************************.9*************************** PP

  AA_permease 390 fRkalkyqgrsieelgfkaallplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfliilvgvklhv 470
                  fR a+k +grsi+el + a+ +++g++l+l ++i+ l++ +++ +++       ++a++f++ yl ++++l++++g+k++ 
   EEA21267.1 419 FRAAWKHNGRSIDELAYVAPWGVYGSYLGLGLNILCLIAEFYVSVQP-------LDAQTFFENYLAAPIVLALYLGWKIYQ 492
                  ******************************************98888.......9***********************986 PP

>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  125.6  41.8   3.7e-40   2.2e-36       8     409 ..      48     465 ..      44     485 .. 0.81

  Alignments for each domain:
  == domain 1  score: 125.6 bits;  conditional E-value: 3.7e-40
  AA_permease_2   8 alvigsvigsgifvkn....laasggpalilwvwiavligslavllvyaElssalprsgGiyvytkaafgkkvaflsawfnwfayvpvlasilsva 99 
                    +++ig +ig+g+fv++    +++ +g++l+ +v +++++  l  ++++ El+ + p +g  y y+ +++ + ++f ++w +++ +++ l++ l++a
     EEA21267.1  48 MIAIGGAIGAGFFVSTggalRTGGPGALLLCYVTVGIML--LQTMWALGELAVMYPVNGAYYDYSLRFIDPSWGFAMGWDYAINWLVILPFELTAA 141
                    689***********9999555555555555555555555..5689999****99*****************************************9 PP

  AA_permease_2 100 asyllnalgpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfssl.stetdtffpn..gwpg..v 190
                    + ++ + + +dl      + + ++++l+++ +i+i+g+++++ + ++l i+ki+  +i +iilg+++ +gg         + ++     + ++  +
     EEA21267.1 142 GITIRY-WREDL-----NVGIWIAVFLVILSAIQIFGVRGYGEVEFVLSIIKIT-AVIGFIILGIVIDCGGAPV-GgYIGGRYWYDPgaFTDFvgF 229
                    999999.78887.....35566778899999**********************5.7788888***996655554.422233233333456665335 PP

  AA_permease_2 191 llgllivlwsfdGfesaanvseevkk..kdvpkaifigllivlvlyllvniaflgvvpd..dei...anlsnlgsvaalffeavggkvvaiivvil 279
                     +++++++++f+G e++   + e  +  k +pka+  ++  ++v+y++ ++ +  +vp   d++   +  +++ s++ +  +++g   + ++++++
     EEA21267.1 230 CSVFTTAAFAFGGTEMSGLAAAETANpaKSIPKACKQVFWRITVFYVVGTLIVGLIVPHnaDYLmnaSGANTSFSPFVVSIKNAGINGLPSVMNAV 325
                    778899*****************5555599****************************95555566433344778899999999999********* PP

  AA_permease_2 280 ialsllgaintavigssrvlealardgvlPrffakvnkfgspiraiiltaivslillllfllas..saaynfllsvsslgliisyllliigalilr 373
                    i++s++  +n+a++gs+r+++a+a+ g+ P+ff+ v+k+g+pi +i+l+  + ++ ++  + ++  +  +++ll++s ++++++++ + ++ +  r
     EEA21267.1 326 ITISVISVANSATFGSTRTIQAMAEKGMAPKFFSYVDKHGRPIWCIVLQIAFGFLAFINEA-SNtgGQIFTWLLALSGISNFFVWGSVCLAHIRFR 420
                    *****************************************************76654443.335788899************************* PP

  AA_permease_2 374 kkrphlkr.........pgkilvaiigalfllfllvalffppkgp 409
                       +h +r         p+ +  + +g+ ++++ l+a f+++++p
     EEA21267.1 421 AAWKHNGRsidelayvaPWGVYGSYLGLGLNILCLIAEFYVSVQP 465
                    999999999999988884444455556666666666666666655 PP

>> DUF4781  Domain of unknown function (DUF4781)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.1   2.6e-05      0.15     110     176 ..     318     383 ..     293     393 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 2.6e-05
     DUF4781 110 latPvaapvllaalvvgvgsavYstgRsiqrLvDrstHeesisltdrearnswLgvaagvvglgaag 176
                 l   ++a++ ++++ v + sa+++ +R iq ++++++  +  s  d++ r+ w  v+  ++g++a  
  EEA21267.1 318 LPSVMNAVITISVISV-ANSATFGSTRTIQAMAEKGMAPKFFSYVDKHGRPIWCIVLQIAFGFLAFI 383
                 4445788888885544.579*********************************99999999999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (554 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       561  (0.0312901); expected 358.6 (0.02)
Passed bias filter:                      275  (0.0153383); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.64u 0.28s 00:00:00.92 Elapsed: 00:00:00.49
# Mc/sec: 3385.13
//
Query:       EEA21268.1  [L=275]
Description: alanyl-tRNA synthetase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.6e-06   26.2   0.2    3.3e-06   25.9   0.2    1.1  1  tRNA-synt_2c  tRNA synthetases class II (A)
    0.00014   21.9   0.1    0.00036   20.6   0.1    1.7  1  tRNA_SAD      Threonyl and Alanyl tRNA synthetase second addi


Domain annotation for each model (and alignments):
>> tRNA-synt_2c  tRNA synthetases class II (A)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.9   0.2   3.7e-10   3.3e-06     468     537 ..      32     105 ..       6     127 .. 0.70

  Alignments for each domain:
  == domain 1  score: 25.9 bits;  conditional E-value: 3.7e-10
                   XXXXXSEEEEEEEEEETTEEEESEEXXXXSSSSCSXXXEEEEESS.EEEEESEEE...EETTEEEEEXSS.XSX CS
  tRNA-synt_2c 468 allkdkefveeveegeevgvvLdrTpfYaesGGqigDeGliekeg.aefrvkdvq...kakgvvlhkgkleegk 537
                   al +++++v +    e+ +vv+d+T f +++GGq +D G++++++   f+v+ v+   + +g v+h g++++++
    EEA21268.1  32 ALDESNRQVFKTGGDEDYVVVVDKTIFHPQGGGQPSDVGTMTGKTgLIFTVTAVRmdvVCDGQVMHLGHFSTDD 105
                   4444555555555666677889*****************88877635677777752214458999988886654 PP

>> tRNA_SAD  Threonyl and Alanyl tRNA synthetase second additional domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.6   0.1   4.1e-08   0.00036       2      34 ..     230     262 ..     229     269 .. 0.81

  Alignments for each domain:
  == domain 1  score: 20.6 bits;  conditional E-value: 4.1e-08
                 EEEEE.TT.EEEEESS---SBGGGC-SEEEECCE CS
    tRNA_SAD   2 rvvsi.GdisvelCgGtHvpnTgeIgafkilsee 34 
                 r v i G  +  +CgGtHv+ T  +g+  + +  
  EEA21268.1 230 RMVNIaG-LDAYPCGGTHVETTDLCGHTTVKKIT 262
                 7889955.89***************998776554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       299  (0.0166769); expected 358.6 (0.02)
Passed bias filter:                      272  (0.015171); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1874.89
//
Query:       EEA21269.1  [L=182]
Description: GNAT family N-acetyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.2e-09   35.6   0.0    1.6e-08   34.9   0.0    1.4  1  Acetyltransf_7   Acetyltransferase (GNAT) domain
    4.5e-07   30.1   0.0    8.1e-07   29.3   0.0    1.4  1  Acetyltransf_1   Acetyltransferase (GNAT) family
    4.6e-05   23.3   0.0     0.0001   22.2   0.0    1.6  1  Acetyltransf_10  Acetyltransferase (GNAT) domain
      0.005   16.8   0.2      0.021   14.8   0.1    2.0  1  FR47             FR47-like protein
  ------ inclusion threshold ------
      0.062   13.4   0.0       0.11   12.6   0.0    1.4  1  Acetyltransf_CG  GCN5-related N-acetyl-transferase


Domain annotation for each model (and alignments):
>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.9   0.0   4.3e-12   1.6e-08       2      75 ..      77     159 ..      76     160 .. 0.75

  Alignments for each domain:
  == domain 1  score: 34.9 bits;  conditional E-value: 4.3e-12
                     TEEEEEEEET..TEEEEEEEEEEES........TCTEEEEE-GGGTTSSHHHHHHHH...TTSEEEEE.EEEETHHHHHHHHHHTTEE CS
  Acetyltransf_7   2 kgevfVaedd..gkivGfialslld........aeitrlaVdpeyrgkGiGraLlea...aekgiile.qlelnaekaikfYeklGFe 75 
                     k+++++ae++  g ++G i l+ +         a +  l+V pe+rg G+G aL++    +  g  l+ q  l   +a+++Y++ G++
      EEA21269.1  77 KERCWIAERKgdGAFLGSIMLVKDResvdpskiAKLRLLFVEPEARGMGLGAALVRQcysR-IG--LWtQGILL--AARRLYAREGYK 159
                     679****999989999*999888889999865444444*****************962331.12..23222232..5899******97 PP

>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.3   0.0   2.3e-10   8.1e-07      29     114 ..      73     155 ..      45     158 .. 0.69

  Alignments for each domain:
  == domain 1  score: 29.3 bits;  conditional E-value: 2.3e-10
                     HSTTC.EEEEEEET..TEEEEEEEEEEEET..TSTTEEEEEEEEESGGGTTSSHHHHHHHHHHHHHHHTTESEEEEEEETTEHHHHHHHHH CS
  Acetyltransf_1  29 sleae.gllvaeed..geliGfisllkipd..ekggvayieslaVspeyrgkGlGsaLlealeerareegikkivlaveedndaairlYek 114
                      ++ + ++++ae+   g  +G i+l k+ +     + a ++ l+V pe+rg+GlG aL++++  r        i l+++    aa+rlY +
      EEA21269.1  73 YDPSKeRCWIAERKgdGAFLGSIMLVKDREsvDPSKIAKLRLLFVEPEARGMGLGAALVRQCYSR--------IGLWTQGILLAARRLYAR 155
                     223334888877774466**************889************************998763........344444445566666655 PP

>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.2   0.0   2.9e-08    0.0001      30     109 ..      77     161 ..      47     174 .. 0.77

  Alignments for each domain:
  == domain 1  score: 22.2 bits;  conditional E-value: 2.9e-08
  Acetyltransf_10  30 ealllvaeeg..gkivGviel.rdgs........hisllfVdpeyrgqGigkaLleaveeeaekdgikleltvnaspyavpfYeklGFkav 109
                      +  +++ae++  g  +G i l +d++        ++ llfV+pe+rg G+g+aL+ ++ +++  + ++  +      +a+++Y + G+k v
       EEA21269.1  77 KERCWIAERKgdGAFLGSIMLvKDREsvdpskiaKLRLLFVEPEARGMGLGAALVRQCYSRIGLWTQG--IL----LAARRLYAREGYKLV 161
                      55678888873355669998889999999999999**********************99998666444..22....345666666666665 PP

>> FR47  FR47-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.1   5.7e-06     0.021      21      51 ..     109     139 ..     101     167 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 5.7e-06
                 TSSEEEEEE-GGG-SSSHHHHHHHHHHHHHH CS
        FR47  21 ggelgalqvlpehrrrGlgsrlvkalakeia 51 
                 +  l  l v+pe+r++Glg  lv++   +i 
  EEA21269.1 109 IAKLRLLFVEPEARGMGLGAALVRQCYSRIG 139
                 5678999*****************9988875 PP

>> Acetyltransf_CG  GCN5-related N-acetyl-transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   3.1e-05      0.11      26      52 ..     111     137 ..      86     139 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 3.1e-05
  Acetyltransf_CG  26 dfthTeVpeelrGkGiAkkLvkaaldd 52 
                      ++   +V++e rG G++++Lv+++   
       EEA21269.1 111 KLRLLFVEPEARGMGLGAALVRQCYSR 137
                      566679*****************9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (182 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       298  (0.0166211); expected 358.6 (0.02)
Passed bias filter:                      289  (0.0161191); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.39u 0.25s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1358.14
//
Query:       EEA21270.1  [L=501]
Description: FAD binding oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      7e-31  106.8   6.3    1.3e-30  106.0   6.3    1.4  1  FAD_binding_4   FAD binding domain
    1.2e-06   28.5   1.8    1.2e-06   28.5   1.8    1.9  2  BBE             Berberine and berberine like
  ------ inclusion threshold ------
       0.04   13.9   0.0      0.085   12.8   0.0    1.5  1  NAD_Gly3P_dh_N  NAD-dependent glycerol-3-phosphate dehydrogen


Domain annotation for each model (and alignments):
>> FAD_binding_4  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.0   6.3   2.1e-34   1.3e-30       3     138 ..      80     212 ..      79     213 .. 0.94

  Alignments for each domain:
  == domain 1  score: 106.0 bits;  conditional E-value: 2.1e-34
                    EEEEESSHHHHHHHHHHHHHCTSCEEEESSSTTEESTTCSCCEEEEEETTS--EEEEETTTTEEEEETTSBHHHHHHHHHHHTTECSSGGGTTCGS CS
  FAD_binding_4   3 avvrpeseeevaaalrlaneaglpvlvrGgGssllgqavatggvvldlsrlnrileideeegtatveaGvtlgdlvealaakglllglepgsgipg 98 
                    a+v+++++eev++++++a+++ +p+ v++gG s++g++ + gg+v+dl r+nr +++++++ ++ ve+G++++d++ a+a++gl++   p++ ++ 
     EEA21270.1  80 AIVKVTTAEEVSTVVEFAAKRYIPFAVLSGGYSTNGASSTYGGIVIDLGRMNR-VDVQSSSSIVSVEGGAKWADVDTAAAQHGLAVV-GPTA-SQL 172
                    79*********************************88888*************.89999********************88888887.5555.678 PP

                    BHHHTTTTT-EETTEEGG--HHGTEEEEEEEETTSEEEEE CS
  FAD_binding_4  99 tvGGaiatnagGygsekyGlirdnvlglevvladGevvrl 138
                    +vGG+++++++G+   kyGli dn+++++vvladG++ ++
     EEA21270.1 173 GVGGTTLGGGIGWLTGKYGLIIDNLVEAQVVLADGSITTA 212
                    9***********************************9986 PP

>> BBE  Berberine and berberine like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       1.1   6.5e+03       2      22 ..     266     286 ..     265     288 .. 0.73
   2 !   28.5   1.8     2e-10   1.2e-06       2      40 ..     453     488 ..     452     491 .. 0.92

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1.1
                 -TTS--GGG-HHHHHHHHG.GG CS
         BBE   2 YvNyrdldlgkewgerYFg.gN 22 
                 YvN  d  l  e +  +Fg  N
  EEA21270.1 266 YVNDLDSKLE-EDQGLFFGfTN 286
                 9999999888.77777777555 PP

  == domain 2  score: 28.5 bits;  conditional E-value: 2e-10
                 -TTS--GGG-HHHHHHHHGGGHHHHHHHHHHH-TT--S- CS
         BBE   2 YvNyrdldlgkewgerYFggNferLvkvKtkyDPdNvFr 40 
                 Y N+  +d      +  Fg+N++rL ++K+ yDP+NvFr
  EEA21270.1 453 YPNFTGFDAN---ARDLFGDNLPRLKELKKYYDPRNVFR 488
                 7888889998...999**********************9 PP

>> NAD_Gly3P_dh_N  NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   1.4e-05     0.085      62     132 ..      36     109 ..      20     115 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.4e-05
                     -HHHHHTT--EEEE---HHHHHHHHHHHCCC--TT-EEEE---SE..ET.TTEEHHHHHHHHH-S--.EEEEES CS
  NAD_Gly3P_dh_N  62 dlaealkgadiivlvvPsqalrevlkklkgllkkkailvsliKGi..eegtlkllsevieeelkeek.vavlsG 132
                     d  +a ++ + + +  P+q +r+ l  ++++  + a   +liKG   +  t + +s+v+e   k++   avlsG
      EEA21270.1  36 DRWSATSEKEAVCVSSPHQSIRSLLSPIQEHHLTYADTTMLIKGAivKVTTAEEVSTVVEFAAKRYIpFAVLSG 109
                     5667888999999*******************************888999***************999*****9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (501 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       533  (0.0297284); expected 358.6 (0.02)
Passed bias filter:                      477  (0.0266049); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 3387.06
//
Query:       EEA21271.1  [L=471]
Description: FAD binding oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      4e-31  107.6   7.0    9.1e-31  106.5   6.5    1.9  2  FAD_binding_4  FAD binding domain


Domain annotation for each model (and alignments):
>> FAD_binding_4  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.5   6.5   5.1e-35   9.1e-31       3     138 ..      48     180 ..      46     181 .. 0.94
   2 ?   -2.2   0.0      0.17     3e+03      16      37 ..     429     450 ..     420     463 .. 0.60

  Alignments for each domain:
  == domain 1  score: 106.5 bits;  conditional E-value: 5.1e-35
                    EEEEESSHHHHHHHHHHHHHCTSCEEEESSSTTEESTTCSCCEEEEEETTS--EEEEETTTTEEEEETTSBHHHHHHHHHHHTTECSSGGGTTCGS CS
  FAD_binding_4   3 avvrpeseeevaaalrlaneaglpvlvrGgGssllgqavatggvvldlsrlnrileideeegtatveaGvtlgdlvealaakglllglepgsgipg 98 
                    a+v+++++eev++++++a+++ +p+ v++gG s++g++ + gg+v+dl r+nr +++++++ ++ ve+G++++d++ a+a++gl++   p++ ++ 
     EEA21271.1  48 AIVKVTTAEEVSTVVEFAAKRYIPFAVLSGGYSTNGASSTYGGIVIDLGRMNR-VDVQSSSSIVSVEGGAKWADVDTAAAQHGLAVV-GPTA-SQL 140
                    89*********************************88888*************.89999********************88888887.5555.678 PP

                    BHHHTTTTT-EETTEEGG--HHGTEEEEEEEETTSEEEEE CS
  FAD_binding_4  99 tvGGaiatnagGygsekyGlirdnvlglevvladGevvrl 138
                    +vGG+++++++G+   kyGli dn+++++vvladG++ ++
     EEA21271.1 141 GVGGTTLGGGIGWLTGKYGLIIDNLVEAQVVLADGSITTA 180
                    9***********************************9986 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.17
                    HHHHHHHCTSCEEEESSSTTEE CS
  FAD_binding_4  16 alrlaneaglpvlvrGgGssll 37 
                    ++ l +++++ ++++G+ s+ +
     EEA21271.1 429 TICLVSKNSRSITILGTCSGNG 450
                    5556666666666666655544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (471 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       475  (0.0264934); expected 358.6 (0.02)
Passed bias filter:                      399  (0.0222544); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.26s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 3294.27
//
Query:       EEA21272.1  [L=469]
Description: FAD binding oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.2e-31  107.2   6.5    9.1e-31  106.5   6.5    1.4  1  FAD_binding_4  FAD binding domain
    1.1e-06   28.7   1.8    1.1e-06   28.7   1.8    1.9  2  BBE            Berberine and berberine like


Domain annotation for each model (and alignments):
>> FAD_binding_4  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.5   6.5     1e-34   9.1e-31       3     138 ..      48     180 ..      46     181 .. 0.94

  Alignments for each domain:
  == domain 1  score: 106.5 bits;  conditional E-value: 1e-34
                    EEEEESSHHHHHHHHHHHHHCTSCEEEESSSTTEESTTCSCCEEEEEETTS--EEEEETTTTEEEEETTSBHHHHHHHHHHHTTECSSGGGTTCGS CS
  FAD_binding_4   3 avvrpeseeevaaalrlaneaglpvlvrGgGssllgqavatggvvldlsrlnrileideeegtatveaGvtlgdlvealaakglllglepgsgipg 98 
                    a+v+++++eev++++++a+++ +p+ v++gG s++g++ + gg+v+dl r+nr +++++++ ++ ve+G++++d++ a+a++gl++   p++ ++ 
     EEA21272.1  48 AIVKVTTAEEVSTVVEFAAKRYIPFAVLSGGYSTNGASSTYGGIVIDLGRMNR-VDVQSSSSIVSVEGGAKWADVDTAAAQHGLAVV-GPTA-SQL 140
                    89*********************************88888*************.89999********************88888887.5555.678 PP

                    BHHHTTTTT-EETTEEGG--HHGTEEEEEEEETTSEEEEE CS
  FAD_binding_4  99 tvGGaiatnagGygsekyGlirdnvlglevvladGevvrl 138
                    +vGG+++++++G+   kyGli dn+++++vvladG++ ++
     EEA21272.1 141 GVGGTTLGGGIGWLTGKYGLIIDNLVEAQVVLADGSITTA 180
                    9***********************************9986 PP

>> BBE  Berberine and berberine like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0      0.68   6.1e+03       2      22 ..     234     254 ..     233     256 .. 0.73
   2 !   28.7   1.8   1.2e-10   1.1e-06       2      40 ..     421     456 ..     420     459 .. 0.92

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.68
                 -TTS--GGG-HHHHHHHHG.GG CS
         BBE   2 YvNyrdldlgkewgerYFg.gN 22 
                 YvN  d  l  e +  +Fg  N
  EEA21272.1 234 YVNDLDSKLE-EDQGLFFGfTN 254
                 9999999888.77777777555 PP

  == domain 2  score: 28.7 bits;  conditional E-value: 1.2e-10
                 -TTS--GGG-HHHHHHHHGGGHHHHHHHHHHH-TT--S- CS
         BBE   2 YvNyrdldlgkewgerYFggNferLvkvKtkyDPdNvFr 40 
                 Y N+  +d      +  Fg+N++rL ++K+ yDP+NvFr
  EEA21272.1 421 YPNFTGFDAN---ARDLFGDNLPRLKELKKYYDPRNVFR 456
                 7888889998...999**********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (469 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       453  (0.0252663); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.25s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 3097.99
//
Query:       EEA21273.1  [L=563]
Description: multicopper oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.8e-38  131.2   2.7    1.8e-38  131.2   2.7    2.6  4  Cu-oxidase_3  Multicopper oxidase
    1.6e-37  128.3  11.4    9.2e-37  125.8   0.1    3.2  3  Cu-oxidase_2  Multicopper oxidase
    2.7e-35  121.8   1.5    1.4e-34  119.5   0.4    2.3  2  Cu-oxidase    Multicopper oxidase


Domain annotation for each model (and alignments):
>> Cu-oxidase_3  Multicopper oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  131.2   2.7     3e-42   1.8e-38       6     118 ..      69     182 ..      64     183 .. 0.93
   2 ?   -3.1   0.0       1.3   7.6e+03      30      45 ..     243     258 ..     219     275 .. 0.60
   3 ?   -1.5   0.0      0.41   2.4e+03      33      56 ..     433     456 ..     426     465 .. 0.81
   4 ?   -3.2   0.0       1.4   8.3e+03      84     109 ..     497     521 ..     489     525 .. 0.78

  Alignments for each domain:
  == domain 1  score: 131.2 bits;  conditional E-value: 3e-42
                   EEECTTEESEEEEEECTSSBS-EEEEETT-EEEEEEEE-S...SS-B-EEEET--S-GG.....GSCSGGG-B-TT-EEEEEEE--S-SEEEEEEE- CS
  Cu-oxidase_3   6 tvsplggterevitvNgqfpgptievregdtvvvnvtNkl...dentsihwhGlqqrktswmDGvpgvtqcpiqpgesftyrftvkqqagtlwYhsh 99 
                     +p+g + r + ++Ng++pgpti++++gd+vvv+vtN+l   +++tsihwhG++q+ t+  DGv  vt+cp +p+++ ty+++++q +gt+wYhsh
    EEA21273.1  69 ILAPDGIP-RYTQVINGSVPGPTIHANWGDEVVVHVTNQLsssNNGTSIHWHGIRQNFTNQNDGVVSVTECPTAPENTITYKWRATQ-YGTTWYHSH 163
                   45666766.999****************************998889*****************************************.********* PP

                   -TTHHHTT-EEEEEEE-HH CS
  Cu-oxidase_3 100 lslqqaaGlaGaiiiedke 118
                   +slq ++G++Gai+i+ ++
    EEA21273.1 164 FSLQAWEGVFGAIVIDGPA 182
                   ****9**********9875 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 1.3
                   EEETT-EEEEEEEE-S CS
  Cu-oxidase_3  30 evregdtvvvnvtNkl 45 
                   ++++g++ +++++N +
    EEA21273.1 243 KFKSGKSYRLRLVNTA 258
                   3445555555555554 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 0.41
                   TT-EEEEEEEE-SSS-B-EEEET- CS
  Cu-oxidase_3  33 egdtvvvnvtNkldentsihwhGl 56 
                    ++ v v v+ +l  +  ih+hG 
    EEA21273.1 433 ANKWVYVLVQSSLGVPHPIHLHGH 456
                   467899999999999999999996 PP

  == domain 4  score: -3.2 bits;  conditional E-value: 1.4
                   EEE--S-SEEEEEEE--TTHHHTT-E CS
  Cu-oxidase_3  84 rftvkqqagtlwYhshlslqqaaGla 109
                    f+ ++  g  + h h+ ++ + Gla
    EEA21273.1 497 AFQTDN-PGAWLMHCHIGFHTVGGLA 521
                   577777.8999999999999888876 PP

>> Cu-oxidase_2  Multicopper oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.9   4.6    0.0033        20      32     132 ..      88     177 ..      72     181 .. 0.74
   2 ?   -1.5   0.0      0.32   1.9e+03      31      70 ..     238     278 ..     206     314 .. 0.66
   3 !  125.8   0.1   1.5e-40   9.2e-37       3     134 ..     405     527 ..     403     530 .. 0.91

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.0033
                   SEEEEEETTEEEEEEEEE-SSS...-EEEEESS-EEEEEEEEECCCCCCTCCSSGCCGSSCBSEEEE-TTEEEEEEEES.S-EEEEEEESSHHHHHT CS
  Cu-oxidase_2  32 tnvitlpkgevveiviqnntkl...pHPfHlHGhdfqvlgrgpgndpeedpksynlenpvrrdtvqvppggwvairfkadnpGvwllHCHilwHldq 125
                    ++i+++ g+ v + ++n+ +      ++H+HG +    +++ g               v+     + p+ ++++ ++a++ G   +H+H+   + +
    EEA21273.1  88 GPTIHANWGDEVVVHVTNQLSSsnnGTSIHWHGIRQNFTNQNDGV--------------VSVTECPTAPENTITYKWRATQYGTTWYHSHFSLQAWE 170
                   5667777788888888886666555589*****988888888887..............22233444568899999999999999999999877777 PP

                   T-EEEEE CS
  Cu-oxidase_2 126 Gmalqfv 132
                   G  +++v
    EEA21273.1 171 GVFGAIV 177
                   7776665 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.32
                   SSEEEEEETTEEEEEEEEE-SSS-E.EEEESS-EEEEEEEE CS
  Cu-oxidase_2  31 ntnvitlpkgevveiviqnntklpH.PfHlHGhdfqvlgrg 70 
                   ++ + +++ g+  ++ + n++  +H +f ++ h++ v++ +
    EEA21273.1 238 QRFTTKFKSGKSYRLRLVNTALDTHfSFSIDNHTMTVIAAD 278
                   44455555677777888887777654666666666666555 PP

  == domain 3  score: 125.8 bits;  conditional E-value: 1.5e-40
                   S-SCCCCCCCEEEEEEEEEEEETC.CTTTSSEEEEEET.TEEEEEEEEE-SSS-EEEEESS-EEEEEEEEECCCCCCTCCSSGCCGSSCBSEEEE-T CS
  Cu-oxidase_2   3 ppklptllqltsgneeaseitnge.efsentnvitlpk.gevveiviqnntklpHPfHlHGhdfqvlgrgpgndpeedpksynlenpvrrdtvqvpp 97 
                   ++++ptllq+           n+e  +s ++ vi++++ +++v++ +q +  +pHP+HlHGhdf+vl++g+g+  +++++  +++np rrdt+++ +
    EEA21273.1 405 DWENPTLLQIY----------NNEtSWSSTEGVIQVDEaNKWVYVLVQSSLGVPHPIHLHGHDFFVLAQGTGT-YDPNTAVSKFNNPARRDTAMLLA 490
                   78899999999..........44449************9*********************************9.555555556789*********** PP

                   TEEEEEEEES.S-EEEEEEESSHHHHHTT-EEEEEEE CS
  Cu-oxidase_2  98 ggwvairfkadnpGvwllHCHilwHldqGmalqfvvr 134
                   gg++ ++f++dnpG+wl+HCHi +H+  G+a+qfv+r
    EEA21273.1 491 GGYLLLAFQTDNPGAWLMHCHIGFHTVGGLAIQFVER 527
                   ***********************************97 PP

>> Cu-oxidase  Multicopper oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.5   0.4   2.3e-38   1.4e-34       5     158 ..     193     340 ..     189     341 .. 0.88
   2 ?    0.7   0.0     0.086   5.1e+02      59     101 ..     425     468 ..     371     522 .. 0.71

  Alignments for each domain:
  == domain 1  score: 119.5 bits;  conditional E-value: 2.3e-38
                 EEEEEETCBCTTSCBC.HSSCHCHHHHHTT--SEEEETTBSS.......CTTTTSGGGEEEEETTEEEEEEEESSS-BEEEEETSB-EEEEEETCETTS CS
  Cu-oxidase   5 itlsDwyhkdakelekellasgkapadtppvpdavlingkggfnatladkdgaslatltvepgktyrlriinvsaddslnfsIeGHkltVvevDgvyve 103
                 i+l+Dw h++ +el    ++ + +    pp   + ling + ++ + ++    + +t+++++gk yrlr++n+++d++++fsI++H++tV+++D v+ve
  EEA21273.1 193 IVLTDWSHETPDELFY--FDAKHG----PPYLENGLINGMNVYKNGDNQ--VGQRFTTKFKSGKSYRLRLVNTALDTHFSFSIDNHTMTVIAADLVPVE 283
                 78***********888..333334....8999*******8888877555..689********************************************* PP

                 EEEESCEEE-TTEEEEEEEEE-SS..SEEEEEEEEGSSSCHHHHTTSEEEEEEEEST CS
  Cu-oxidase 104 pvevdsldIavGqrysvlvtanqa..pgnYwivasgrsnlieafengtaaailryse 158
                 p++++ l I+ +qry+v+v+a+qa   +++w++a  +++ +++  + + ++i+ y++
  EEA21273.1 284 PFTTNVLTIGIAQRYDVIVKADQAqvADKFWMRAVPQTDCSSNNSTDNIRGIIYYGN 340
                 *********************996689*******85556567777888888888876 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.086
                 SGGGEEEEETTEEEEEEEESSS-BEEEEETSB-EEEEEE.TCET CS
  Cu-oxidase  59 latltvepgktyrlriinvsaddslnfsIeGHkltVvev.Dgvy 101
                  ++++v+   +    ++  s+   +++ ++GH + V +  +g+y
  EEA21273.1 425 EGVIQVDEANKWVYVLVQSSLGVPHPIHLHGHDFFVLAQgTGTY 468
                 56777888888888888888889999999999888876554444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (563 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       427  (0.0238162); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.23s 00:00:00.76 Elapsed: 00:00:00.40
# Mc/sec: 4250.70
//
Query:       EEA21274.1  [L=190]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (190 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       336  (0.0187406); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.39u 0.25s 00:00:00.64 Elapsed: 00:00:00.39
# Mc/sec: 1461.15
//
Query:       EEA21275.1  [L=163]
Description: NUDIX domain, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-21   75.3   0.1      5e-21   75.1   0.1    1.1  1  NUDIX     NUDIX domain


Domain annotation for each model (and alignments):
>> NUDIX  NUDIX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.1   0.1   2.8e-25     5e-21       3     123 ..       6     132 ..       4     142 .. 0.78

  Alignments for each domain:
  == domain 1  score: 75.1 bits;  conditional E-value: 2.8e-25
                 EEEEEEE.EEETTSE.....EEEEEESSSSTTT.EESSEEECBTTSHHHHHHHHHHHHHHSEEEEEEEEEEEEEEEEEEEEEEEE..EEEEEEEEE.EE CS
       NUDIX   3 rravgvv.llnekge.....vLlvrrskkpfpg.WelPgGkvepgEtpeeAArREleEEtGleaellellgrlhylapydgpygd..eheilyvfl.ee 91 
                 r++vgv+ l+ +++      +++ +r +++ +g ++lPgG++e gEtpe++A+RE+ EEtGle  + ++l+       ++++ +   +h+i+++++  +
  EEA21275.1   6 RVGVGVFvLYSSQESstnprFVMGKRLNSHGSGtYALPGGHLEFGETPEDCAIREVLEETGLEISEPKFLT------ATNDYMPAegKHYITLFMVcVR 98 
                 789****8888886689999*******999999889**************************999999999......2233333343677776666766 PP

                 ECSGCSST..STTTEEEEEEEEHHHHHHHHTHCT CS
       NUDIX  92 vegelepn..denevsevrwvpleellkeklaae 123
                 +++e+ p+  +++ ++++ wv+ e+l+ ++++++
  EEA21275.1  99 KNEEQVPQvlEPHKCESWDWVSWEDLKSATDEQN 132
                 6666666689****************44333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (163 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       423  (0.0235931); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.28s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1132.22
//
Query:       EEA21276.1  [L=303]
Description: hypothetical protein PMAA_050890 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-18   67.6   0.0    3.1e-18   66.3   0.0    1.6  2  HsbA      Hydrophobic surface binding protein A
  ------ inclusion threshold ------
      0.021   13.6   1.8       0.23   10.2   0.0    2.0  2  Hex_IIIa  Hexon-associated protein (IIIa)


Domain annotation for each model (and alignments):
>> HsbA  Hydrophobic surface binding protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.1       1.1     1e+04      57      68 ..      47      58 ..      36      70 .. 0.64
   2 !   66.3   0.0   3.4e-22   3.1e-18       5     118 ..     125     238 ..     123     240 .. 0.97

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 1.1
                ---HHHHHHHHH CS
        HsbA 57 pltdeealalaq 68
                 +t eea+al+q
  EEA21276.1 47 GITREEAQALVQ 58
                466677777665 PP

  == domain 2  score: 66.3 bits;  conditional E-value: 3.4e-22
                 HHHHHHHHHHHHHHHHHHHH--SH..HHHHHHHHHHHHHHHHHHHHHHHTS----HHHHHHHHHHHH.HCHHHHHHHHHHHHHTHHHHHHHT-HHHHHH CS
        HsbA   5 isdittistavtaldtavnafnGgasalpilsasnalvsaikkattdaqasapltdeealalaqavq.tLepdvkaaldaliaKkpafdkagltslvls 102
                 +s+i+ i +++++l+ +++ ++Gg  a+ +l+   ++++aik+++++ + + +l++ +a+ l+++++ tL+p v+ +++ali+K   + + g++s+vl+
  EEA21276.1 125 KSVIDVIAERMKTLNYHIDDYHGG-PATFLLTGPREIIQAIKDGIQKFRRQVSLDEHDANLLVAYIEkTLKPPVQWVIEALIEKEKPLVARGFRSQVLQ 222
                 78999******************5.79************************************************************************ PP

                 HHHHHHHHHHHHHHHH CS
        HsbA 103 sLqdlkaasdaLsdal 118
                 sLq++k+ +++L d +
  EEA21276.1 223 SLQNMKNPVEQLRDII 238
                 ************9976 PP

>> Hex_IIIa  Hexon-associated protein (IIIa)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   2.5e-05      0.23     228     324 ..      21     118 ..       2     144 .. 0.79
   2 ?    2.8   0.4    0.0044        40      38      95 ..     219     275 ..     211     280 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 2.5e-05
    Hex_IIIa 228 gyllknkeesvsaPkelsarqlgllkflqkslvdkldkdnedadialetl.sysldPslyeankvfvrklityleaalarsPvyfrelvldkywiPPa 324
                 +y l+  +e     ++ s +q  + + + ++  ++l + +++a  a+ t  +  +dP+l  +  vf+  li + + ala +  y    ++++   PP+
  EEA21276.1  21 NYDLRAAHEKDKQKRKRSKKQISIEQGITREEAQALVQGQVEASHAVTTTpAAPVDPELPASQPVFLPSLIIFSLSALAPASSYIDHYITKNRPDPPS 118
                 455555555555777899****************************99872567**************************999998777666666664 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.0044
    Hex_IIIa  38 nvqeslqalvgdvkslqddlirskdianlsnqvllttfldslyktvdfGqrnyeafkk 95 
                 +v +slq + + v  l+d +i  k i  + +q   ++f +   k +++G   ++ f +
  EEA21276.1 219 QVLQSLQNMKNPVEQLRD-IISRKIIQSAQKQYFTKEFNNITIKVIQQGIDAFDNFIH 275
                 46789***********86.6666889999999999999999999*****999999865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (303 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1379  (0.0769145); expected 358.6 (0.02)
Passed bias filter:                      786  (0.0438396); expected 358.6 (0.02)
Passed Vit filter:                        73  (0.00407162); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 2003.93
//
Query:       EEA21277.1  [L=543]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.6e-42  145.0  50.3    5.1e-42  144.1  49.9    1.6  2  MFS_1          Major Facilitator Superfamily
    1.6e-17   63.2  27.5    2.1e-15   56.2  27.5    2.2  1  TRI12          Fungal trichothecene efflux pump (TRI12)
    4.5e-10   39.0  13.3    4.5e-10   39.0  13.3    2.6  3  Sugar_tr       Sugar (and other) transporter
     0.0023   18.1   0.0      0.013   15.7   0.0    2.3  1  Mpv17_PMP22    Mpv17 / PMP22 family
  ------ inclusion threshold ------
       0.11   12.7   0.7       0.27   11.4   0.1    2.0  2  CRM1_repeat_3  CRM1 / Exportin repeat 3


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  144.1  49.9   1.4e-45   5.1e-42       1     352 [.      34     433 ..      34     434 .. 0.89
   2 ?   -2.2   0.0      0.42   1.5e+03     146     172 ..     485     510 ..     479     530 .. 0.55

  Alignments for each domain:
  == domain 1  score: 144.1 bits;  conditional E-value: 1.4e-45
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlg 98 
                 l+++ +++al+++il +alp +++ dl+ s+s+  ++ t y l+++v+++++G+lsd +Grr +l ++ll+f +g++++ + +++  +ll++rvlqG+g
  EEA21277.1  34 LAFVSLIVALDATILVTALP-TISADLNGSGSASFWVGTSYLLASSVLMPFMGSLSDILGRREILTAALLFFTVGSTVAGV-AQSMdILLLGRVLQGVG 130
                 68999***************.******************************************************888886.66677************ PP

       MFS_1  99 agalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee......... 188
                 +++++p+ ++++ d++p + r+++ +++++++++G+i gpl+ggl+++++ Wr++fy++ +++ +++v++ + ++ + ++++  ++  +          
  EEA21277.1 131 GAGILPMTQIVLCDIVPLRFRPKYASVAQLAWAIGSITGPLIGGLMVQHVTWRWIFYLNLPFCGISMVIVPFIIRLRTKQSSILAKLARIdwiggslfi 229
                 **************************************************************************9999999999999999********* PP

       MFS_1 189 ..........................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglll 245
                                                           k+ ++ p++    a+++++  ++  +++ + ++++++ l+++ ly+ +v  +s  + 
  EEA21277.1 230 gsmtsflmavtwggvdhawdsaatlaplligivgtvvsilweKWGAREPFIR--LAIFSNRSALAGYYCAMTQGLVLFIQLYYVSLYFTSVKAFS-PVH 325
                 *****************99999999999999999998888855555555555..77777776656777777779999999999999*********.799 PP

       MFS_1 246 aglllallalvgailallagrlsdrlgr.rrrlllallllllaalglallavtssavllll.vlvliGfglgfvfpsllalasdlappeeagtasglfn 342
                 +g+ +  ++ v ++ +++++ l+ r+gr r++l+ + ++ +la+ +l+l+  +  +++ ++ +l+++G+g+g+   +l+ + + +a       a+  +n
  EEA21277.1 326 TGVSVIPVSSVLVPTGIIVSLLISRTGRiRWALWSGWIFEVLASGLLILMDGS-ITTWRWVlILMTVGLGHGLLLQALTFVPQTMAKDTDESYAATMYN 423
                 997777788888888*************5556666666666666666666666.777777746666********************9999999999*** PP

       MFS_1 343 tagslggalg 352
                 + +++g+a+g
  EEA21277.1 424 FSRTFGMAFG 433
                 *******998 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.42
       MFS_1 146 sslgWravfyilaivsllafvlfllll 172
                  ++++  vf +  ++++l+++ + ll+
  EEA21277.1 485 YAASFKNVFELSLALTVLGAL-VSLLI 510
                 333555555555566665554.33333 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.2  27.5   5.9e-19   2.1e-15      49     565 ..      37     525 ..      19     541 .. 0.70

  Alignments for each domain:
  == domain 1  score: 56.2 bits;  conditional E-value: 5.9e-19
       TRI12  49 fslnvvatyfvlqas..asalpnilqdvgqsensslf.stlwttgqavsilvmgrltdrfgrrpfvilthilglvgaivgctatkfntllaamtllgva 144
                 +sl v      l+a+   +alp i  d+  s   s++  t + +  +v +  mg l+d +grr ++ ++ ++  vg+ v   a+ ++ ll    l gv 
  EEA21277.1  37 VSLIV-----ALDATilVTALPTISADLNGSGSASFWvGTSYLLASSVLMPFMGSLSDILGRREILTAALLFFTVGSTVAGVAQSMDILLLGRVLQGVG 130
                 33333.....3333311579********999888875268899999999999*********************************************95 PP

       TRI12 145 .agpagasplfvgelmsnktkflgllivsipvvvtsglspylgqrlaiqgswrwifyiyiitsaiavllivvwyyppsfaqlhgkkvrkreelakldwi 242
                  ag    + +++ +++  + +     +  +   + s  +p +g  +    +wrwify+ +    i+++++      p + +l  k+ +   +la++dwi
  EEA21277.1 131 gAGILPMTQIVLCDIVPLRFRPKYASVAQLAWAIGSITGPLIGGLMVQHVTWRWIFYLNLPFCGISMVIV------PFIIRLRTKQSSILAKLARIDWI 223
                 366666777788888765544333334444444555679****9999999*********99999876543......77899****************** PP

       TRI12 243 giilvivgvslfllgvswggkpnspwnsakviglissglgslvvfalyevygkpvrpivppalfkdtrgfvcillissimgamnlslviiypqqvvnif 341
                 g  l i  ++ fl+ v+wgg  +  w+sa  +  +  g+   vv  l+e +g   +p++  a+f +   +      +    am   lv++     v ++
  EEA21277.1 224 GGSLFIGSMTSFLMAVTWGGV-DHAWDSAATLAPLLIGIVGTVVSILWEKWGA-REPFIRLAIFSNRSAL------AGYYCAMTQGLVLFIQLYYVSLY 314
                 ********************7.578***99999888999889999*******7.57********987654......55677899999999888999999 PP

       TRI12 342 gsslknweeta..w.msatasfgtgagvvvlgslfhlvrhirwqilvgalwltaflgamssvnrdnknaaialsvls.gfvvawaqditmllvqfittd 436
                  +s+k +        +   +s+   +g+ ++  l+     irw +  g ++     g +  ++         l +++ g+  +   +   ++ q ++ d
  EEA21277.1 315 FTSVKAFSPVHtgVsVIPVSSVLVPTGI-IVSLLISRTGRIRWALWSGWIFEVLASGLLILMDGSITTWRWVLILMTvGLGHGLLLQALTFVPQTMAKD 412
                 9999999754300202233444444554.4566777778899988887554443333333333333333333333321333333333333344555555 PP

       TRI12 437 edlgvafavvaaarpfagsiftaafislysnrypkelashlssalrgtdipqasfsslleaaksgrie.avkalpgmtteiaavvsramadsytasyan 534
                  d   a ++   +r                  +   ++  +  ++    + q  +s+ l+a+ +   +  v  l  mt++    +   +  +y+as+ n
  EEA21277.1 413 TDESYAATMYNFSRT-----------------FGMAFGVAIGGTMFQNRLKQHLISAGLDATIASNADqYVAVLNTMTDQ---SLRDGILAAYAASFKN 491
                 555555555555554.................444444444444444444444445555555544444146778888875...456677789******* PP

       TRI12 535 vyyfamalgvipiiaslcmrd..ldr.yltdhvp 565
                 v+ +++al v+  + sl +r   +dr ++t+hv 
  EEA21277.1 492 VFELSLALTVLGALVSLLIRKsvFDRkHVTEHVL 525
                 ******************9973355424555553 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.0  13.3   1.2e-13   4.5e-10      17     190 ..      35     202 ..      30     205 .. 0.90
   2 ?   -3.4   0.4      0.88   3.2e+03      50      96 ..     222     267 ..     215     276 .. 0.60
   3 ?    3.0  10.3      0.01        37       9     159 ..     289     438 ..     282     461 .. 0.83

  Alignments for each domain:
  == domain 1  score: 39.0 bits;  conditional E-value: 1.2e-13
                 HCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHH CS
    Sugar_tr  17 gvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGig 115
                 ++++ +++l +++    l + +++ + s + s ++  ++l+ + +   f+g l+d++GR+ +l +a ++f +g+ + ++a+   s+ +l++gRvl G+g
  EEA21277.1  35 AFVSLIVALDATILVTALPTISADLNGSGSASFWVGTSYLLASSVLMPFMGSLSDILGRREILTAALLFFTVGSTVAGVAQ---SMDILLLGRVLQGVG 130
                 667777777777777777777777777888889999999999999999*********************************...*************** PP

                 HHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGG CS
    Sugar_tr 116 vGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllf 190
                   ++  ++ + +  i p + R +  s+ qla+++G + +  +g  + +      wr+ ++l+l +  + ++++ f
  EEA21277.1 131 GAGILPMTQIVLCDIVPLRFRPKYASVAQLAWAIGSITGPLIGGLMVQHVT---WRWIFYLNLPFCGISMVIVPF 202
                 ******************************************988877666...********9999888888777 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 0.88
                 HHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-T CS
    Sugar_tr  50 livsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaa 96 
                 +i +++++G++ + l+a ++g  ++  +  +++ + ++ig+v ++++
  EEA21277.1 222 WIGGSLFIGSMTSFLMAVTWGG-VDHAWDSAATLAPLLIGIVGTVVS 267
                 6667777777777777776664.345555555555555555555555 PP

  == domain 3  score: 3.0 bits;  conditional E-value: 0.01
                 HHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTH.HHHHHHHHHHHHHHHHHHH-TTTTSS-TGGG CS
    Sugar_tr   9 gllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGR.kkslliaavlfvigavlqaaakgknsvevli 106
                 + l gY  ++  + + +++  +   + +s+++     v +g++v  ++ + + ++++++ll+ r GR +++l  + ++ v ++ l ++ +g  +++  +
  EEA21277.1 289 SALAGYYCAMTQGLVLFIQLYYVSLYFTSVKAFS--PVHTGVSVIPVSSVLVPTGIIVSLLISRTGRiRWALWSGWIFEVLASGLLILMDGSITTWRWV 385
                 6778888888888888888777777777777664..589999999999999999*************556666677777999********999999999 PP

                 GGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHH CS
    Sugar_tr 107 vgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifgl 159
                 +  + vG+g Gl     +   + +A+++  ++  ++y+++ tfG+ ++  +g 
  EEA21277.1 386 LILMTVGLGHGLLLQALTFVPQTMAKDTDESYAATMYNFSRTFGMAFGVAIGG 438
                 99999****************************************99988764 PP

>> Mpv17_PMP22  Mpv17 / PMP22 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   3.6e-06     0.013      29      58 ..     134     163 ..     129     164 .. 0.93

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 3.6e-06
  Mpv17_PMP22  29 vWppaqlinFyfvPlkfRvlfvnvvslgWn 58 
                  + p+ q+++   vPl+fR  +++v +l+W 
   EEA21277.1 134 ILPMTQIVLCDIVPLRFRPKYASVAQLAWA 163
                  68***************************7 PP

>> CRM1_repeat_3  CRM1 / Exportin repeat 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1   7.5e-05      0.27       9      22 ..     156     169 ..     153     171 .. 0.85
   2 ?   -3.2   0.1       2.6   9.5e+03      29      46 ..     494     511 ..     488     513 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 7.5e-05
  CRM1_repeat_3   9 nlnkLCWAiGSISg 22 
                    ++ +L+WAiGSI g
     EEA21277.1 156 SVAQLAWAIGSITG 169
                    5779********98 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.6
  CRM1_repeat_3  29 EkrfLvtvikdLLnLcee 46 
                    E ++ +tv+  L++L+ +
     EEA21277.1 494 ELSLALTVLGALVSLLIR 511
                    566778899999998755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (543 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       577  (0.0321825); expected 358.6 (0.02)
Passed bias filter:                      247  (0.0137766); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.61u 0.27s 00:00:00.88 Elapsed: 00:00:00.48
# Mc/sec: 3435.54
//
Query:       EEA21278.1  [L=471]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.4e-133  446.0  18.3   1.6e-133  445.7  18.3    1.0  1  Glyco_hydro_76  Glycosyl hydrolase family 76
  ------ inclusion threshold ------
       0.52    9.3   9.0        1.2    8.1   0.5    2.7  3  Glyco_hydro_88  Glycosyl Hydrolase Family 88


Domain annotation for each model (and alignments):
>> Glyco_hydro_76  Glycosyl hydrolase family 76
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  445.7  18.3  1.8e-137  1.6e-133       1     361 [.      33     395 ..      33     400 .. 0.98

  Alignments for each domain:
  == domain 1  score: 445.7 bits;  conditional E-value: 1.8e-137
                     SXHHHHHHHHHHHHHHCETTECCTCTCBSCES-GHHHHHHHHHHHHHHHHHCTTCCCHHHHHHHHHCCCTCEE-SSSTTCTCSSEHHHHHHHHHH CS
  Glyco_hydro_76   1 siksaaatiakgllkyYkgnesggtpgnlpdpyywWeagalfgalidywrltgdstyndlitqallaqagenydympanqsrtegnDDqafwgla 95 
                     s+ksaa+++a++ ++yY+  es+ +pg+++ +  wWe ga+f+ li+yw++tgd++yn+l+ ++l +q ge +d++p+n+s+++gnDDq fw+la
      EEA21278.1  33 SLKSAASVAAASAVNYYNNRESKLIPGKFDGT--WWEGGAFFTFLINYWHWTGDDQYNALVAEGLSWQGGEANDFFPSNYSSYLGNDDQEFWALA 125
                     789*****************************..************************************************************* PP

                     HHHHHHH.....H--HHHHHHHHHHHHHHHHCB..-SCSCCS-BBSEC..ESS--SEEEHHHHHHHHHHHHHHHHHH--CHHHHHHHHHHHHHHH CS
  Glyco_hydro_76  96 amtaaernfpeptdepswLalAqavfntqasrw..deetcgGGlrWqiftwnsgydyknsisngplfqlaarLarytgnetYlewAekvwdWved 188
                     a+ta e +fp++++ pswL+lAq++fn  ++rw  d+++cgGGlrWq +++ +gyd+kn+isng++fq+aarLaryt+n+tY++wAe vwdW+ +
      EEA21278.1 126 ALTAIEQRFPDNPGHPSWLSLAQGAFNDFVARWevDKSSCGGGLRWQLYPTLAGYDSKNAISNGGFFQIAARLARYTNNNTYATWAEIVWDWSST 220
                     ********************************9445556******************************************************** PP

                     HSCSBTTTS-B-SEEETTTCCEEEE---HHHHHHHHHHHHHHHHHHH.--HHHHHHHHHHHHHHHHHCEEC...TTEEEEEE-TTSTTCCTTHHH CS
  Glyco_hydro_76 189 vgliddedwlvyDgasvednctdinklqwtYnqGtylsgaaylynaT.gdekWldrvkgllnatlstffpd...gnilyevacepsekcnnDqrs 279
                     v+l+d+++w++yD ++++++c+d + +qw+Yn+G y++gaay+yn+T g++kW++ ++glln+t s ffp+   gnil+e+ac p  +cn+Dq++
      EEA21278.1 221 VPLFDNSTWKIYDMTRISKDCKDQDLMQWSYNYGAYITGAAYMYNYTnGATKWKQGIDGLLNTTFSQFFPAeygGNILSEAACDPILTCNRDQVC 315
                     *************************************************************************************999******* PP

                     HHHHHHHHHHHHH..SHHHHHHHHHHHHHHHHHHHTTTB...TTTSB-TTTTTSSCCHHHHHHHHCCHHH............ CS
  Glyco_hydro_76 280 Fkgilarwlaltaqlapetadtiepllrasaeaaakscsggsdgttcglkwlkgtwdgdaglgeqmsaleviqallveekka 361
                     Fkg++a+wl+++a +ap+t+++i p+l+asa  a k+csg   + +cg++w++ t+dg++ ++++msa++++ ++lv+ +++
      EEA21278.1 316 FKGLMANWLSTIALIAPYTYASILPKLQASAVGAGKQCSG--PNSACGMQWFSATYDGTSAIEQEMSAMSIFANALVAFSSS 395
                     ****************************************..8999*****************************9988654 PP

>> Glyco_hydro_88  Glycosyl Hydrolase Family 88
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.5   0.00014       1.2      27      56 ..      65      93 ..      38     130 .. 0.80
   2 ?   -2.0   0.1      0.17   1.5e+03      31      56 ..     188     213 ..     181     221 .. 0.74
   3 ?    6.2   0.5   0.00051       4.6      22      48 ..     244     270 ..     224     290 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00014
                    E.HHHHHHHHHHHHHHHHH--HHHHHHHHH CS
  Glyco_hydro_88 27 wewtnGvflsglleayeatgdkeyldyaka 56
                    w w+ G+f++ l++++ +tgd++y +++++
      EEA21278.1 65 W-WEGGAFFTFLINYWHWTGDDQYNALVAE 93
                    3.**********************999876 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.17
                     HHHHHHHHHHHHHHH--HHHHHHHHH CS
  Glyco_hydro_88  31 nGvflsglleayeatgdkeyldyaka 56 
                     nG f++  ++++ +t++++y  +a+ 
      EEA21278.1 188 NGGFFQIAARLARYTNNNTYATWAEI 213
                     56677777788888888888887765 PP

  == domain 3  score: 6.2 bits;  conditional E-value: 0.00051
                     STTCCE.HHHHHHHHHHHHHHHHH--H CS
  Glyco_hydro_88  22 kkenewewtnGvflsglleayeatgdk 48 
                     ++  +w ++ G++++g +++y++t+  
      EEA21278.1 244 QDLMQWSYNYGAYITGAAYMYNYTNGA 270
                     45579*******************965 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (471 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       477  (0.0266049); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 3310.34
//
Query:       EEA21279.1  [L=407]
Description: monoxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.5e-18   65.1   0.0    9.1e-18   64.6   0.0    1.1  1  FAD_binding_3  FAD binding domain
    0.00051   19.4   0.0      0.057   12.6   0.0    2.1  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
     0.0037   16.9   0.3       0.17   11.4   0.1    2.6  3  DAO            FAD dependent oxidoreductase
  ------ inclusion threshold ------
      0.018   15.6   0.0       0.24   12.0   0.0    2.2  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
      0.094   11.8   0.1       0.17   10.9   0.1    1.4  1  FAD_binding_2  FAD binding domain


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.6   0.0   2.5e-21   9.1e-18       2     315 ..       4     320 ..       3     327 .. 0.77

  Alignments for each domain:
  == domain 1  score: 64.6 bits;  conditional E-value: 2.5e-21
                    EEEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSSS--EEEHHHHHHHHHTT-HHHHHHHSEECCCCEEEEEEECCCC.CEEEEEHH...CH CS
  FAD_binding_3   2 tdVlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlpradglnqrtmellrqlGledrilaegapnelmgealynelsdt.pkaradle...le 93 
                     +VlI G+G a   la  Ls+ G rvv+ve+  +    +    l  + +++ + +Gl d i+++ + + +++++ ++   +         +     
     EEA21279.1   4 LKVLICGGGCAVPALAYWLSKCGHRVVVVERFPDLRASGAQIDLRAQGIDVVKRMGLLDVIRSKLVDEIGFSFVDSQG--RAkA-TVMANKsgkGT 96 
                    58******************************9988888777799999****************97666666655555..3321.22222233334 PP

                    HCST-CEE--HHHHHHHHHHHHHHHTEEETCSEEEECCEECCCCCCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHHHTGGEEEEEEEEEEEEEE CS
  FAD_binding_3  94 sspervtvypqteleriLvehaeerglqvrfktevesleqdeegvtaevrdketgeeetvrakYlvGaDGgrStvrktlgiefegeetvyeagvld 189
                    +s ++   +   +l  +L+e+ ++  ++  f+++ve +eqd+ +v   + d +++       + lvGaDG  S++r+++ ++  ++ ++   + l+
     EEA21279.1  97 QSLTSEFEIMRGDLVGLLYEA-TKDRVEYIFGKQVEYFEQDDGQVMIHFSDGTSDSF-----DLLVGADGQGSRIRQAISTP--TTADL--YTRLN 182
                    556666666777788888887.8899**********************999998877.....9****************977..55555..56788 PP

                    EEEEC.-SCCCTTC...CEEEEECCTTEEEEEECCETEEEEEEEEECCE-GGGSCCCHHHHHHHHHHHHHHTTSSCEE.E....EEEEEEE...EE CS
  FAD_binding_3 190 vlfda.dlsdivep...lvlilsaesrgvmviPlentlerfyvqvearaekeersekfteeevkarlreivgektldv.e....ieevsaw...tv 273
                    v+++   ++++ ++   + + l +  r ++ +  +++++++y++v+ + e+ ++ +k   e+ k+ + + ++++  ++ +    ++ ++++   + 
     EEA21279.1 183 VHIAYyFVPRTEDDsdtSQMYLIPGGRAITRRTHNQHETQVYFMVRDESEELRSLPKAPLEQQKQFWSNRFADAGWQApRflegMKTTESFycqEA 278
                    888886667666668886666667888888888888889999999988888888888888999999998888776665321111333444411134 PP

                    EEEEESSSEETTEEE-GGGTEEE-STTSHHHHHHHHHHHHHH CS
  FAD_binding_3 274 aqrvaekyrkgrvflaGDAaHihpPtgGqGlNtaiqDavnLa 315
                     q   e+++kgrv  +GDAaH+ +P  G+G   +   a+ La
     EEA21279.1 279 VQVHIESWHKGRVVPVGDAAHCASPFSGMGTTGSFVGAYVLA 320
                    4556899***********************988887777776 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.0   1.6e-05     0.057     144     201 ..       5      55 ..       1      83 [. 0.78
   2 !    4.6   0.0    0.0044        16     193     240 ..     117     164 ..     113     179 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.6e-05
                  EEEEES-SHHHHHHHHHHHHHT-EEEEEESSSSSSTTS-HHHHHHHHHHHHHTTEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 144 rivvvGgGyiGvElAaalaklgkevtlveardrllraldkelsaaleealekeGvevk 201
                  +++++GgG     lA  l+k+g++v++ve+ + l        +  ++  l+++G++v+
   EEA21279.1   5 KVLICGGGCAVPALAYWLSKCGHRVVVVERFPDLR-------ASGAQIDLRAQGIDVV 55 
                  799*****99999********************97.......3334444445555544 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.0044
                  HHHTTEEEEESCEEEEEEETTEEEEEEETTSCEEEESEEEE-S-EEES CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 193 lekeGvevklgtsvkeidgngeklevvledgeeidadlvvvavGvrps 240
                   +k+ ve  +g++v+ +++++ ++  + +dg++   dl+v a G   +
   EEA21279.1 117 ATKDRVEYIFGKQVEYFEQDDGQVMIHFSDGTSDSFDLLVGADGQGSR 164
                  67889****************9888***************99987655 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.4   0.1   4.8e-05      0.17       1      39 [.       5      43 ..       5      59 .. 0.87
   2 ?    2.3   0.0     0.028     1e+02     151     206 ..     112     167 ..     107     237 .. 0.59
   3 ?   -1.5   0.0       0.4   1.4e+03     112     142 ..     336     364 ..     246     376 .. 0.56

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 4.8e-05
                EEEEECTSHHHHHHHHHHHHTT..EEEEESSSSTTSSGGGS CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..VtllekgdiagsgaSgr 39
                +v+i GGG +  + Ay+L++ g  V+++e+ +++   aSg+
  EEA21279.1  5 KVLICGGGCAVPALAYWLSKCGhrVVVVERFPDLR--ASGA 43
                599***************999999******97765..6665 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.028
                 HHHHHHHHTT-EEEESECEEEEEEEETCEEEEE.EECTEEEEEEEEEEE--GGGHH..H CS
         DAO 151 alaraaealGveilegtevtgleeedgkvwgve.rttpgendaadavVnaaGawsd..l 206
                 +l+ +a +  ve ++g +v+ +e++dg+v+  + +   g+ d++d +V a G +s+  +
  EEA21279.1 112 GLLYEATKDRVEYIFGKQVEYFEQDDGQVMIHFsD---GTSDSFDLLVGADGQGSRirQ 167
                 6888899999************9999998888664...555557889999998876321 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 0.4
                 TEEEEEHHHHHHHSTTSTTTSEEEEETTEEE CS
         DAO 112 daelldaeevrelepalpgllgalfypdtgq 142
                  +e l++  v+el+  ++++l  lf+p+t +
  EEA21279.1 336 NYEKLRPF-VNELQR-VSPTLIRLFMPETQW 364
                 22334443.333332.112344455555544 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   6.6e-05      0.24       1      59 [.       5      56 ..       5      72 .. 0.86
   2 ?    0.9   0.0      0.19   6.8e+02      50      78 ..     117     144 ..     112     147 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 6.6e-05
                EEEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSSTTSSHHHHHHHHHHHHHTTEEEEC CS
   Pyr_redox  1 kvvvvGgGyiglElAgalaelgkkVtvversdkllrllDeeaskilqeklekngievll 59
                kv++ GgG     lA  l++ g++V vver + l+       ++  q  l+++gi+v+ 
  EEA21279.1  5 KVLICGGGCAVPALAYWLSKCGHRVVVVERFPDLR-------ASGAQIDLRAQGIDVVK 56
                69999****999***********************.......67777778888887765 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.19
                 HHHTTEEEECSEEEEEEEEETTSEEEEEE CS
   Pyr_redox  50 lekngievllntkveeiegsedgvesvkl 78 
                  +k  +e +++++ve +e+++ +v  +++
  EEA21279.1 117 ATKDRVEYIFGKQVEYFEQDDGQVM-IHF 144
                 67888*************9998643.555 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.1   4.8e-05      0.17       2      35 ..       6      39 ..       5      67 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 4.8e-05
                   EEEE--SHHHHHHHHHHHHTTT-EEEEESSSGGG CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGlkvavvekeqefg 35
                   v+++G+G A  a A+ ++++G++v+vve  +  +
     EEA21279.1  6 VLICGGGCAVPALAYWLSKCGHRVVVVERFPDLR 39
                   9***************************988643 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (407 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       576  (0.0321267); expected 358.6 (0.02)
Passed bias filter:                      558  (0.0311228); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.61u 0.31s 00:00:00.92 Elapsed: 00:00:00.50
# Mc/sec: 2468.20
//
Query:       EEA21280.1  [L=332]
Description: aldo-keto reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.3e-42  146.0   0.0    2.6e-42  145.0   0.0    1.5  1  Aldo_ket_red  Aldo/keto reductase family
  ------ inclusion threshold ------
      0.064   13.1   0.6       0.39   10.6   0.1    2.4  2  HTH_23        Homeodomain-like domain
      0.096   12.3   0.0       0.16   11.6   0.0    1.2  1  DUF3251       Protein of unknown function (DUF3251)


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.0   0.0   4.4e-46   2.6e-42       2     292 ..      25     287 ..      24     289 .. 0.93

  Alignments for each domain:
  == domain 1  score: 145.0 bits;  conditional E-value: 4.4e-46
                   EEEE-SSS-ST.TS-HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH-TTTGGG-EEEEEE--SSSTTSSSS-HHHHHHHHHHHHHHHT CS
  Aldo_ket_red   2 lglGtwqlgskeeiskeealellrraleaGinffDtAevYgkgqseellGealkksrkkreeviiatKvdlrdaeiksglskeniresleeslkrLg 98 
                   +glGtwq + +  ++ ee  + + +al  G++++DtA++Y     ee++G a+ +s+++r e+ + tK      + ++++ +    ++l++sl  L+
    EEA21280.1  25 VGLGTWQGQFG-SKAAEELRASIIHALRIGYRLIDTAQYY---GVEEIVGDAVRESGVPRSEITVITKF-----WGEWHHDP---AAALDKSLHDLN 109
                   799***88875.8999999999******************...9*************************.....55555554...578********* PP

                   -S-EEEEEE-S--TTS-.............HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHHHHTTT--EEEEE-B-BTT-HHHHTTHHHHHHHTT CS
  Aldo_ket_red  99 tdyvDllllHrpdpslp............sieevldaleelvkeGkiraiGvSnfsveqlekakkkkkvkivavqveynllreleeegllelckkkg 183
                    +y+D+ll+H+p  +++             + e+++ +e lv   k+raiGvSnf+ + l+ ++++ k+ +v++qve + l    + +l + c+++g
    EEA21280.1 110 IEYIDILLMHWPWAMSSdgkqllrpeespTYVETWKKMEALVG-PKCRAIGVSNFTQKTLSVLLRECKIVPVVNQVELHAL--NPNLKLTPWCEDHG 203
                   **************9999************************9.7************************************..************** PP

                   -EEEEBSTTGGGTTGTTTSS---SSSCCC-------TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTSTT-SEEEE--SSHHHHHHHHGGGG-- CS
  Aldo_ket_red 184 vpliaysplggGlltgkyqseedkedkeprkdlkrdertsknldaaeelselakehgvslaqlalryalsqpavgivipgasnieqlednldalelk 280
                   ++++ +s++ggG+ +++                       k+ + ++ + ++a+ hg+ + +++l++a+  ++++ivip++s+ ++++ n++ +  +
    EEA21280.1 204 IKVMSWSTIGGGAESSQAS---------------------KEILSNPLFTDIAAAHGIPVGAVSLSWAV--QRGIIVIPKSSSTARIDSNIRLV--R 275
                   ************9883333.....................2357899**********************..9**********************..* PP

                   --HHHHHHHHHH CS
  Aldo_ket_red 281 lseeevaeldel 292
                   l+++e+++++++
    EEA21280.1 276 LTDDEIEAINNA 287
                   *********986 PP

>> HTH_23  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.1   6.5e-05      0.39       3      29 ..      39      65 ..      37      67 .. 0.92
   2 ?   -0.5   0.0      0.19   1.2e+03      22      35 ..     233     246 ..     232     253 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 6.5e-05
      HTH_23  3 sereRlrillllaeGlsvreIAreLgv 29
                 e+ R++i+++l+ G++  + A+ +gv
  EEA21280.1 39 AEELRASIIHALRIGYRLIDTAQYYGV 65
                6899*********************98 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.19
      HTH_23  22 eIAreLgvsrrTvy 35 
                 +IA+++g++   v+
  EEA21280.1 233 DIAAAHGIPVGAVS 246
                 8*******987775 PP

>> DUF3251  Protein of unknown function (DUF3251)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   2.7e-05      0.16      41      90 ..     251     300 ..     244     309 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 2.7e-05
                 -SSSEEE-TTT---EEEE-SS-EEEEEEEEEEE-SSSEEEEEEEEESSSS CS
     DUF3251  41 skkgvyLlPgaktparlesqiGrlrvslaniepeadGtrvvLriqgesad 90 
                  ++g+ + P +++ ar++s+i  +r++  +ie+  +  + + ri+  +++
  EEA21280.1 251 VQRGIIVIPKSSSTARIDSNIRLVRLTDDEIEAINNAENTIGRIRLTDNA 300
                 589******************************99999988888877765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (332 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       441  (0.024597); expected 358.6 (0.02)
Passed bias filter:                      416  (0.0232026); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 2222.07
//
Query:       EEA21281.1  [L=332]
Description: aldo-keto reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.3e-42  146.0   0.0    2.6e-42  145.0   0.0    1.5  1  Aldo_ket_red  Aldo/keto reductase family
  ------ inclusion threshold ------
      0.064   13.1   0.6       0.39   10.6   0.1    2.4  2  HTH_23        Homeodomain-like domain
      0.096   12.3   0.0       0.16   11.6   0.0    1.2  1  DUF3251       Protein of unknown function (DUF3251)


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.0   0.0   4.4e-46   2.6e-42       2     292 ..      25     287 ..      24     289 .. 0.93

  Alignments for each domain:
  == domain 1  score: 145.0 bits;  conditional E-value: 4.4e-46
                   EEEE-SSS-ST.TS-HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH-TTTGGG-EEEEEE--SSSTTSSSS-HHHHHHHHHHHHHHHT CS
  Aldo_ket_red   2 lglGtwqlgskeeiskeealellrraleaGinffDtAevYgkgqseellGealkksrkkreeviiatKvdlrdaeiksglskeniresleeslkrLg 98 
                   +glGtwq + +  ++ ee  + + +al  G++++DtA++Y     ee++G a+ +s+++r e+ + tK      + ++++ +    ++l++sl  L+
    EEA21281.1  25 VGLGTWQGQFG-SKAAEELRASIIHALRIGYRLIDTAQYY---GVEEIVGDAVRESGVPRSEITVITKF-----WGEWHHDP---AAALDKSLHDLN 109
                   799***88875.8999999999******************...9*************************.....55555554...578********* PP

                   -S-EEEEEE-S--TTS-.............HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHHHHTTT--EEEEE-B-BTT-HHHHTTHHHHHHHTT CS
  Aldo_ket_red  99 tdyvDllllHrpdpslp............sieevldaleelvkeGkiraiGvSnfsveqlekakkkkkvkivavqveynllreleeegllelckkkg 183
                    +y+D+ll+H+p  +++             + e+++ +e lv   k+raiGvSnf+ + l+ ++++ k+ +v++qve + l    + +l + c+++g
    EEA21281.1 110 IEYIDILLMHWPWAMSSdgkqllrpeespTYVETWKKMEALVG-PKCRAIGVSNFTQKTLSVLLRECKIVPVVNQVELHAL--NPNLKLTPWCEDHG 203
                   **************9999************************9.7************************************..************** PP

                   -EEEEBSTTGGGTTGTTTSS---SSSCCC-------TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTSTT-SEEEE--SSHHHHHHHHGGGG-- CS
  Aldo_ket_red 184 vpliaysplggGlltgkyqseedkedkeprkdlkrdertsknldaaeelselakehgvslaqlalryalsqpavgivipgasnieqlednldalelk 280
                   ++++ +s++ggG+ +++                       k+ + ++ + ++a+ hg+ + +++l++a+  ++++ivip++s+ ++++ n++ +  +
    EEA21281.1 204 IKVMSWSTIGGGAESSQAS---------------------KEILSNPLFTDIAAAHGIPVGAVSLSWAV--QRGIIVIPKSSSTARIDSNIRLV--R 275
                   ************9883333.....................2357899**********************..9**********************..* PP

                   --HHHHHHHHHH CS
  Aldo_ket_red 281 lseeevaeldel 292
                   l+++e+++++++
    EEA21281.1 276 LTDDEIEAINNA 287
                   *********986 PP

>> HTH_23  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.1   6.5e-05      0.39       3      29 ..      39      65 ..      37      67 .. 0.92
   2 ?   -0.5   0.0      0.19   1.2e+03      22      35 ..     233     246 ..     232     253 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 6.5e-05
      HTH_23  3 sereRlrillllaeGlsvreIAreLgv 29
                 e+ R++i+++l+ G++  + A+ +gv
  EEA21281.1 39 AEELRASIIHALRIGYRLIDTAQYYGV 65
                6899*********************98 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.19
      HTH_23  22 eIAreLgvsrrTvy 35 
                 +IA+++g++   v+
  EEA21281.1 233 DIAAAHGIPVGAVS 246
                 8*******987775 PP

>> DUF3251  Protein of unknown function (DUF3251)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   2.7e-05      0.16      41      90 ..     251     300 ..     244     309 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 2.7e-05
                 -SSSEEE-TTT---EEEE-SS-EEEEEEEEEEE-SSSEEEEEEEEESSSS CS
     DUF3251  41 skkgvyLlPgaktparlesqiGrlrvslaniepeadGtrvvLriqgesad 90 
                  ++g+ + P +++ ar++s+i  +r++  +ie+  +  + + ri+  +++
  EEA21281.1 251 VQRGIIVIPKSSSTARIDSNIRLVRLTDDEIEAINNAENTIGRIRLTDNA 300
                 589******************************99999988888877765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (332 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       441  (0.024597); expected 358.6 (0.02)
Passed bias filter:                      416  (0.0232026); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.40
# Mc/sec: 2488.93
//
Query:       EEA21282.1  [L=461]
Description: cellobiohydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   6.4e-107  357.8   1.4   8.6e-107  357.4   1.4    1.1  1  Glyco_hydro_6  Glycosyl hydrolases family 6
    2.8e-12   46.4  14.2    2.8e-12   46.4  14.2    2.5  3  CBM_1          Fungal cellulose binding domain
  ------ inclusion threshold ------
       0.14   12.6  15.1       0.43   11.0  15.1    1.8  1  MGC-24         Multi-glycosylated core protein 24 (MGC-24), s
        7.8    6.8   8.5         15    5.9   8.5    1.4  1  DUF4680        Domain of unknown function (DUF4680)


Domain annotation for each model (and alignments):
>> Glyco_hydro_6  Glycosyl hydrolases family 6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  357.4   1.4  1.9e-110  8.6e-107      14     306 .]     129     426 ..     117     426 .. 0.97

  Alignments for each domain:
  == domain 1  score: 357.4 bits;  conditional E-value: 1.9e-110
  Glyco_hydro_6  14 daalaakaakvakvptavWldriakieelrkaldeavaqakaeg...avvvlVvYnlPgRDCaaqaSaGelasaaa.lekYkeyidaiaagigkys 105
                    + +laa+a+k a++p++vWld++ak++++ ++l+++ a++ka++    +  +VvY+lP+RDCaa aS+Ge++ a++ +++Yk+yid+i+a++++++
     EEA21282.1 129 TGTLAAAATKAAEIPSFVWLDTAAKVPTMGTYLANIEAANKAGAtppIAGIFVVYDLPDRDCAAAASNGEYTVANNgVANYKAYIDSIVAQLKAHP 224
                    558899********************************9999988888889********************************************* PP

  Glyco_hydro_6 106 dlravvvlEpDslanlvtnlsvekCaeaaaaaerlaglayAvkkLkalpnvavYlDaghsgwlgWeknleeaaellakvvkaaagvakvdGfalnv 201
                    d+++++++EpDslan+vtnls++kC+ea++a  ++++++yA+ +L+  pnva+Y+Dagh+gwlgW++nl++aa+l+a+v+k+a+++a+++G+++nv
     EEA21282.1 225 DVHTILIIEPDSLANMVTNLSTAKCTEAQPA--YYECVNYALINLNL-PNVAMYIDAGHAGWLGWSANLSPAAQLFATVYKNASSPAALRGLVTNV 317
                    *******************************..*************9.************************************************ PP

  Glyco_hydro_6 202 snynateea.....teanksvdekkYakalskalvaaglpalahfviDtsRnGkqgkerkdageWCNppgrglGerpttstgdplvdaylWvKppG 292
                    +nyna++ +     t+ ++++de+ Y++als+ l+++g+p+ ahf++DtsRnG q++++k++g+WCN  g+g+G++ptt+tgdpl da++WvKp+G
     EEA21282.1 318 ANYNAWSISsapsyTSGDSNYDEQLYVNALSPLLTSNGWPN-AHFIMDTSRNGVQPTQQKAWGDWCNLIGTGFGVAPTTNTGDPLEDAFVWVKPGG 412
                    ******9889***999***********************98.7***************************************************** PP

  Glyco_hydro_6 293 eSDGtcdrsaaeag 306
                    eSDGt+++sa++++
     EEA21282.1 413 ESDGTSNSSATRYD 426
                    ********999875 PP

>> CBM_1  Fungal cellulose binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.4  14.2   6.3e-16   2.8e-12       1      29 []      23      51 ..      23      51 .. 0.98
   2 ?   -3.7   1.5       2.8   1.2e+04      24      29 .]     111     116 ..     111     116 .. 0.88
   3 ?   -2.2   0.2      0.92   4.1e+03      19      29 .]     246     256 ..     245     257 .. 0.73

  Alignments for each domain:
  == domain 1  score: 46.4 bits;  conditional E-value: 6.3e-16
       CBM_1  1 lwgQCGGigWtGpTtCvsgatCtyqNeyY 29
                +wgQCGG+g+tG+T+C++g+tC++qN+yY
  EEA21282.1 23 VWGQCGGQGYTGATSCAAGSTCSTQNPYY 51
                5**************************** PP

  == domain 2  score: -3.7 bits;  conditional E-value: 2.8
       CBM_1  24 yqNeyY 29 
                 y N+yY
  EEA21282.1 111 YANPYY 116
                 68**** PP

  == domain 3  score: -2.2 bits;  conditional E-value: 0.92
       CBM_1  19 gatCtyqNeyY 29 
                  a+Ct+  + Y
  EEA21282.1 246 TAKCTEAQPAY 256
                 58999877665 PP

>> MGC-24  Multi-glycosylated core protein 24 (MGC-24), sialomucin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0  15.1   9.7e-05      0.43      17      93 ..      18      98 ..       9     108 .. 0.59

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 9.7e-05
      MGC-24 17 enstCvWleCkgeekskcsenstvedCsvvn..vtelcsaaskst..pkptnstaktttkpsstttstsvatsgttnttvt 93
                e+++ vW +C g+  + +++ ++ + Cs+ n   ++ ++a+ +st   k+t+st+  tt+  +ttt+++++t+++t++t +
  EEA21282.1 18 EAQQSVWGQCGGQGYTGATSCAAGSTCSTQNpyYAQCIPATATSTtlVKTTSSTSVGTTSAPTTTTTKATTTKASTTATTA 98
                577899*****9888777777777889988832344444444444456777777766655444444444443333333322 PP

>> DUF4680  Domain of unknown function (DUF4680)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   8.5    0.0033        15       5      76 ..      26     100 ..      21     106 .. 0.73

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0033
     DUF4680   5 qLggrrakGlrgresgarCaqekpieaaavedvpaggel...ptGsrarvpaaPdsassqrassarsatrqaara 76 
                 q gg+   G  +   g++C++++p+ a  ++ +++++ l   +  +  ++++aP +++ + + +  s+t  +a a
  EEA21282.1  26 QCGGQGYTGATSCAAGSTCSTQNPYYAQCIPATATSTTLvktTSSTSVGTTSAPTTTTTKATTTKASTTATTAAA 100
                 6788999999999*****************999988754211444456778889888888665555555555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (461 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       772  (0.0430587); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.58u 0.25s 00:00:00.83 Elapsed: 00:00:00.42
# Mc/sec: 3321.92
//
Query:       EEA21283.1  [L=280]
Description: UDP-galactose 4-epimerase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.2e-18   66.6   0.2    5.3e-17   62.1   0.2    2.0  1  Epimerase        NAD dependent epimerase/dehydratase family
      1e-10   41.1   0.0    1.5e-10   40.6   0.0    1.2  1  3Beta_HSD        3-beta hydroxysteroid dehydrogenase/isomeras
    8.4e-07   29.1   0.0    1.4e-06   28.3   0.0    1.3  1  NAD_binding_10   NAD(P)H-binding
    4.8e-06   26.2   0.0    1.2e-05   24.9   0.0    1.7  2  GDP_Man_Dehyd    GDP-mannose 4,6 dehydratase
    0.00013   21.2   0.6     0.0004   19.6   0.6    1.8  1  RmlD_sub_bind    RmlD substrate binding domain
     0.0014   17.9   0.6     0.0046   16.1   0.6    1.7  1  Polysacc_synt_2  Polysaccharide biosynthesis protein
      0.007   16.5   0.0      0.011   15.8   0.0    1.4  1  DapB_N           Dihydrodipicolinate reductase, N-terminus
  ------ inclusion threshold ------
       0.01   16.2   0.0      0.017   15.5   0.0    1.4  1  Semialdhyde_dh   Semialdehyde dehydrogenase, NAD binding doma
      0.016   14.8   0.1      0.025   14.1   0.1    1.3  1  NmrA             NmrA-like family


Domain annotation for each model (and alignments):
>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.1   0.2   2.7e-20   5.3e-17       1     176 [.       3     179 ..       3     228 .. 0.76

  Alignments for each domain:
  == domain 1  score: 62.1 bits;  conditional E-value: 2.7e-20
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHCEEEE--TT-HH.HHHHHHHHHT-SEEEE--S---HHHHHHSHHHHHHHHTHHHHHH CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledlelveldltdrs.alerlfkeeqpdavihlAavggvaassedpadfieknlqgtlnl 98 
                 i +tGa+G +G+ lvk + e+g++ + ++r  +++   ++   e+ ++d+ ++  a  ++fk  ++da+ihlAav ++    + + ++ ++n++ + n 
  EEA21283.1   3 IAITGARGSVGKTLVKLCSEAGHHTVQINRTHTEHDGTLNS--EMRTADIANDYgAALEAFK--GCDAIIHLAAVPDPVG--KANWYVHNNNVNAAFNG 95 
                 689*******************9999999995555544444..8999999877668888889..9*******99777766..6778999********** PP

                 HHHHHHHTCTEEEEEEEGGGGT......SCSS...SSBSTCSTTS----SSHHHHHHHHHHHHHHHHHHHH.T-EEEEEEESEEESTT CS
   Epimerase  99 leaarkagvkrllflsSsevYG......kdae...qpkeettltgplkpnspYaaaKlageklveayaaqy.glnaiilrlfnlyGpr 176
                 ++aa + g++r+ ++sS+   G      +  +    p +e++   p +p+ +Ya+aK+ +e +++ +++ + gl++ +lr+  +    
  EEA21283.1  96 FHAAGELGINRICYASSVNAIGlafankP-LHfdyFPINEDA---PQRPTDAYALAKAEAEYQARCFTDWFpGLSIACLRIHEVAPLK 179
                 **********************7775531.123424699999...99*********************************98775443 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.6   0.0   7.3e-14   1.5e-10       1     154 [.       4     152 ..       4     156 .. 0.82

  Alignments for each domain:
  == domain 1  score: 40.6 bits;  conditional E-value: 7.3e-14
   3Beta_HSD   1 vvtGgaGFlGralvkeLvrleelkevrvlDlrespelleelskvnvkkviegDvtd.kdkleealegvdvvihlaslvdvagkltedeimkvnvkGTrn 98 
                 ++tG++G +G++lvk   ++++ ++v+   ++  ++ ++ + +++++   ++D+ +      ea +g d++ihla++ d  gk +   + + nv+   n
  EEA21283.1   4 AITGARGSVGKTLVKLCSEAGH-HTVQ---INRTHTEHDGTLNSEMR---TADIANdYGAALEAFKGCDAIIHLAAVPDPVGKANWY-VHNNNVNAAFN 94 
                 59************99888886.5554...44555555666677666...7888651567789*******************77666.99********* PP

   3Beta_HSD  99 vleacvkagvrvlvYtSsaevvgpnslgeeilngd..EeleyeslhqdaypesKalaE 154
                    a+ + g++++ Y Ss++++g  + +++++      ++  ++ ++day+  Ka aE
  EEA21283.1  95 GFHAAGELGINRICYASSVNAIGLAFANKPLHFDYfpINEDAPQRPTDAYALAKAEAE 152
                 *****************************999432113555667799**********9 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.3   0.0   7.1e-10   1.4e-06       1     102 [.       7     116 ..       7     159 .. 0.68

  Alignments for each domain:
  == domain 1  score: 28.3 bits;  conditional E-value: 7.1e-10
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHHCTTTCEEEE--TT.-CCHHHHHHTT-SEEEES-.....--TCC.........HHHHHHH CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpeklaeleaeeglevvegdvt.dvedlaealkgadaVvsal.....ggggk.........deegakn 80 
                     GA G+vG+ lvk   ++g+h+v +   ++e+      + + e+ ++d+  d  +  ea+kg+da++  +         +         + ++a n
      EEA21283.1   7 GARGSVGKTLVKLCSEAGHHTVQINRTHTEHDG----TLNSEMRTADIAnDYGAALEAFKGCDAIIHLAavpdpV---GkanwyvhnnNVNAAFN 94 
                     9***********999997555555444455544....45778888888625799**********98888455552...03336665334444999 PP

                     HHHHHHHCT--EEEEEEETTTT CS
  NAD_binding_10  81 ivdaakeagvkRfvlvsaigvg 102
                        aa e g++R+ + s++++ 
      EEA21283.1  95 GFHAAGELGINRICYASSVNAI 116
                     99***************98874 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.9   0.0   6.2e-09   1.2e-05       2     166 ..       5     157 ..       4     169 .. 0.79
   2 ?   -2.9   0.0       1.7   3.4e+03     309     320 ..     264     275 ..     212     277 .. 0.70

  Alignments for each domain:
  == domain 1  score: 24.9 bits;  conditional E-value: 6.2e-09
                    EETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE--TT-.HHHHHHHHHHHT-SEEEE--S---HHHHTTSHH CS
  GDP_Man_Dehyd   2 iTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkgDltD.ssslerllaevqpdevynLAAqshVdvsfekPe 96 
                    iTG  G +G  l++l  e g++ + i r +++ + g++             n ++  +D+ +   +  ++++ +  d++++LAA      +     
     EEA21283.1   5 ITGARGSVGKTLVKLCSEAGHHTVQINRTHTE-HDGTL-------------NSEMRTADIANdYGAALEAFKGC--DAIIHLAAVPDPVGK--ANW 82 
                    9********************99997554433.22333.............34567899975266777788776..9*******7543333..336 PP

                    HHHHHHTHHHHHHHHHHHHCT..TTSEEEEEEEGGGG-S-........SSSSB-TTS-----SHHHHHHHHHHHHHHH CS
  GDP_Man_Dehyd  97 ytaevnvlGtlrLLeairalglekkvrfyqaStsEvYGkv........qevpqtEttpfyPrsPYaaaKlyadwivvn 166
                    y+ ++nv ++++ + a+ +lg++   r+  aS+    G +        +  p++E+ p +P+  Ya aK+ a++ ++ 
     EEA21283.1  83 YVHNNNVNAAFNGFHAAGELGIN---RICYASSVNAIGLAfankplhfDYFPINEDAPQRPTDAYALAKAEAEYQARC 157
                    9999*****************96...9***********9865433333357889*****************9998775 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.7
                    -THHHHHHH--- CS
  GDP_Man_Dehyd 309 daskakeeLgWk 320
                     ++ka + LgW+
     EEA21283.1 264 TTDKAARLLGWT 275
                    467888888886 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.6     2e-07    0.0004       1      63 [.       1      75 [.       1     157 [. 0.71

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 2e-07
                   EEEEEESTTSHHHHHHHHHCTTTSEEEEEE-TT.............T--TTSHHHH.HHHHHHH--SEEEE------ CS
  RmlD_sub_bind  1 mkilvtGanGqlGseLakqlaeeglevlaltre.............eldltdaeav.aellkeakpdvvvnaAAyta 63
                   mki +tGa+G +G+ L+k+ +e+g++++ ++r+             ++d+++   +  e++k   +d+++++AA  +
     EEA21283.1  1 MKIAITGARGSVGKTLVKLCSEAGHHTVQINRThtehdgtlnsemrTADIANDYGAaLEAFKG--CDAIIHLAAVPD 75
                   89****************************999999999998877777776554430344444..899***999754 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.6   2.3e-06    0.0046       1     131 [.       3     115 ..       3     119 .. 0.80

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 2.3e-06
                      EEEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH......-TTEEEE....E--T.T-HHHHHHHTT..T-SEEEE------HHHH CS
  Polysacc_synt_2   1 vlvtGagGsiGselvrqilkkkpkkiillerdElklyeiekeleeelkkkklkveivpvigdv.rdkerlekaleelkvdvvfhaAAlKhVPlv 93 
                      + +tGa Gs+G++lv+ + +   +++ +  ++  +  ++++e++    +           +d+ +d     +a++  ++d+++h AA+   P+ 
       EEA21283.1   3 IAITGARGSVGKTLVKLCSEAGHHTVQINRTHTEHDGTLNSEMR----T-----------ADIaNDYGAALEAFK--GCDAIIHLAAVPD-PVG 78 
                      679****************9999999887766666666666552....2...........344157788899999..**********865.766 PP

                      HHSHHHHHHHHHHHHHHHHHHHHHTT-SEEEEEEEGGG CS
  Polysacc_synt_2  94 eenpleaiktNvlgtenvieaaieagvkkvvliStDKA 131
                        n+  + ++Nv ++ n  +aa e g++++ + S+  A
       EEA21283.1  79 KANW-YVHNNNVNAAFNGFHAAGELGINRICYASSVNA 115
                      6665.5789********************999987555 PP

>> DapB_N  Dihydrodipicolinate reductase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   5.7e-06     0.011       1      42 [.       1      40 [.       1      93 [. 0.66

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 5.7e-06
                EEEEEETTTSHHHHHHHHHHHHSTTEEEEEEEETTCSTTTTT CS
      DapB_N  1 ikvavvGasGrmGkevvkaveeaedlelvaavdrkeselegk 42
                +k+a++Ga+G +Gk++vk+ +ea ++++     ++e  ++g+
  EEA21283.1  1 MKIAITGARGSVGKTLVKLCSEAGHHTVQINRTHTE--HDGT 40
                89********************66666554433333..3332 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.5   0.0   8.6e-06     0.017       1      70 [.       2      67 ..       2      82 .. 0.65

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 8.6e-06
                    EEEEETTTSHHHHHHHHHHHC..TSSEEEEEEEESTTTTTSBHHHHSGGGTTTECEBEEE.GGGGGCTT-SEE CS
  Semialdhyde_dh  1 kvaivGatGyvGqellrlLee..hpevelvvllsssrsaGkklaeavkaleegkdlkved.vdeeelkevdiv 70
                    k+ai Ga+G vG+ l++l +e  h  v++ +  ++++++G+  +e+ +    ++d+  +  +  e++k++d +
      EEA21283.1  2 KIAITGARGSVGKTLVKLCSEagHHTVQINR--THTEHDGTLNSEM-R----TADIANDYgAALEAFKGCDAI 67
                    79*******************5555555555..5555345444444.4....344444434455667777755 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.1   1.3e-05     0.025       1     104 [.       3     114 ..       3     128 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 1.3e-05
                 EEESSTTSHHHHHHHHHHHHHT-EEEEEES-S-SHHHHHHHHSTTEEEES-TT-HHHHHHHHTT-SEEEE---GG...........S-HHHHHHHHHHH CS
        NmrA   1 IlviGaTGrqGksvvrallkaghkvralvRdtkselakslkeaGvelvkgdlddkeslvealkgvdvvfsvtgfy...........skeiedgkklvdA 88 
                 I+++Ga G+ Gk +v+   +agh++  + R  ++e   +l+++  +  ++ ++d+    ea+kg d+++   ++            +++++   +  +A
  EEA21283.1   3 IAITGARGSVGKTLVKLCSEAGHHTVQINRT-HTEHDGTLNSEMRT--ADIANDYGAALEAFKGCDAIIHLAAVPdpvgkanwyvhNNNVNAAFNGFHA 98 
                 89**********************9766665.55555566654333..445788899999999999999888765778888888888888888888888 PP

                 HHHHS-SEEEEEE--- CS
        NmrA  89 akeaGvkhfiySslgd 104
                 a e G++++ y+s ++
  EEA21283.1  99 AGELGINRICYASSVN 114
                 8888888888887665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (280 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       347  (0.0193541); expected 358.6 (0.02)
Passed bias filter:                      317  (0.0176809); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 1963.48
//
Query:       EEA21284.1  [L=273]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.13   12.8   0.0       0.22   12.2   0.0    1.3  1  DUF4772   Domain of unknown function (DUF4772)


Domain annotation for each model (and alignments):
>> DUF4772  Domain of unknown function (DUF4772)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   1.2e-05      0.22      28     100 ..     151     229 ..     132     236 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 1.2e-05
     DUF4772  28 q.vkvpsevqqeleanleglapetaytvlfdgirqveefseee.Ligpgfqalagv..slqpgqkvyvt..YnGrevaG 100
                    ++p + ++++++n   +  ++aytv   +  ++++  +++ ++gp++++  ++  ++ +gq vy t  Y G + +G
  EEA21284.1 151 AhNHQPLAKSNTQRFNNVVYNFQAAYTVSNTSEDSYHDIINNHfIVGPSTTSSSDAsyQINSGQIVYATgnYLGTNKDG 229
                 347999*************************999****988883668**9999999556779*****975577776666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (273 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       404  (0.0225333); expected 358.6 (0.02)
Passed bias filter:                      234  (0.0130515); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.40
# Mc/sec: 2056.26
//
Query:       EEA21285.1  [L=146]
Description: hypothetical protein PMAA_050970, partial [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (146 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       547  (0.0305092); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.25s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 1014.41
//
Query:       EEA21286.1  [L=155]
Description: hypothetical protein PMAA_050980 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.3e-29  101.4   0.0    5.9e-29  101.2   0.0    1.0  1  Glyco_hydro_88  Glycosyl Hydrolase Family 88


Domain annotation for each model (and alignments):
>> Glyco_hydro_88  Glycosyl Hydrolase Family 88
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.2   0.0   3.3e-33   5.9e-29     199     342 ..       1     151 [.       1     153 [. 0.92

  Alignments for each domain:
  == domain 1  score: 101.2 bits;  conditional E-value: 3.3e-33
                     HHHHHHHHHS-TT-TTHHHHHHHHHHHHHHHHCTS-TTSSEBSBTT-TT...TTSSBEHHHHHHHHHHHHHHHHTTSS-HHHHHHHHHHHHHHHH CS
  Glyco_hydro_88 199 aglaevlelLpekekarqelinllrdlvkalaklqdeeglWhqilddgs...kesylEtSatalfvygLakgvnkglldkkkykkvaqkawkall 290
                     ++l++vl+ Lp++++ +  l  ++++l+ al++ +d++g W  +++ +    +++y E S+ta+f+yg +kg++kg+ld+ +y+++a +a++a++
      EEA21286.1   1 MALVDVLDWLPQSHPGYSRLLSYFTELAMALQRNWDSHGGWWLVMEAPYpgmAGNYIECSGTAMFIYGFLKGIRKGYLDRSSYTQTATRAYNAIV 95 
                     89*******************************************987544689***************************************** PP

                     HC...EE-TTS-EEE-SEETS--SCTC..HHHHTS-EESS-HHHHHHHHHHHHHHHH CS
  Glyco_hydro_88 291 kk...aveedGqllvkqvsvgtgiggd..dyYksvdvnsiedygvgafllalievlr 342
                     +k     e  G+l+ ++++ + + g+   +yY+s++v+++   g g+f+ a++e++ 
      EEA21286.1  96 EKfvgGNETTGMLTWEGTVNVGS-GNAsyEYYISQPVVENHLNGAGPFVYASVEFEA 151
                     **876688999999998876655.33356*************************975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (155 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       337  (0.0187964); expected 358.6 (0.02)
Passed bias filter:                      285  (0.015896); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.26s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 1145.11
//
Query:       EEA21287.1  [L=320]
Description: MYB family conidiophore development protein FlbD, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-25   89.3   1.8    2.1e-14   53.4   0.2    2.5  2  Myb_DNA-binding  Myb-like DNA-binding domain
    2.1e-18   66.3   3.9    1.1e-14   54.4   0.1    2.6  2  Myb_DNA-bind_6   Myb-like DNA-binding domain
     0.0088   16.2   0.0      0.042   14.0   0.0    2.0  2  DUF2774          Protein of unknown function (DUF2774)
  ------ inclusion threshold ------
      0.026   14.5   0.0      0.094   12.7   0.0    1.9  2  SLIDE            SLIDE
      0.098   12.7   0.3       0.31   11.1   0.1    1.9  2  DUF3701          Phage integrase protein


Domain annotation for each model (and alignments):
>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.4   0.2   5.9e-18   2.1e-14       1      45 [.       7      52 ..       7      53 .. 0.97
   2 !   35.0   0.1   3.4e-12   1.2e-08       5      43 ..      63     101 ..      60     103 .. 0.94

  Alignments for each domain:
  == domain 1  score: 53.4 bits;  conditional E-value: 5.9e-18
                     CSSSBHHHHHHHHHHHHHHT.TCHHHHHHHHTSS-HHHHHHHHHHH CS
  Myb_DNA-binding  1 rgkWteeEdelLleavkkhG.nrWkkIaerlggRtekqcrsrwrny 45
                     rg+W +eEd+ Ll++v+++G n+W +I++ +  R++kqcr+r+++ 
       EEA21287.1  7 RGPWVQEEDNTLLQLVHEQGpNNWVRISQQMHFRSPKQCRERFHQN 52
                     89*****************************************986 PP

  == domain 2  score: 35.0 bits;  conditional E-value: 3.4e-12
                      BHHHHHHHHHHHHHHTTCHHHHHHHHTSS-HHHHHHHHH CS
  Myb_DNA-binding   5 teeEdelLleavkkhGnrWkkIaerlggRtekqcrsrwr 43 
                      ++eE + +++ v+++G+rW++Ia+rlg+R+++++++ w+
       EEA21287.1  63 SAEEGLMIERMVNEMGKRWAEIARRLGNRSDNAVKNWWN 101
                      789999*****************************9886 PP

>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.4   0.1     3e-18   1.1e-14       1      56 [.      10      66 ..      10      70 .. 0.97
   2 !   12.4   0.6   3.9e-05      0.14      12      46 ..      73     107 ..      68     114 .. 0.87

  Alignments for each domain:
  == domain 1  score: 54.4 bits;  conditional E-value: 3e-18
  Myb_DNA-bind_6  1 WteeEdeiLlklvekyg.ndWknIaealnrRtpkqcfdrwknkLrpkisrkkwskee 56
                    W +eEd +Ll+lv ++g n+W  I++++++R+pkqc++r+++ L+p++++++ s+ee
      EEA21287.1 10 WVQEEDNTLLQLVHEQGpNNWVRISQQMHFRSPKQCRERFHQNLKPSLNHTPISAEE 66
                    889**************88************************************97 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 3.9e-05
  Myb_DNA-bind_6  12 lvekygndWknIaealnrRtpkqcfdrwknkLrpk 46 
                      v ++g+ W +Ia+ l++R+ +++++ w+   + k
      EEA21287.1  73 MVNEMGKRWAEIARRLGNRSDNAVKNWWNGNMNRK 107
                     577899**********88**********9976665 PP

>> DUF2774  Protein of unknown function (DUF2774)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0      0.93   3.3e+03       9      26 ..      22      40 ..      19      44 .. 0.75
   2 !   14.0   0.0   1.2e-05     0.042       5      36 ..      69     101 ..      65     109 .. 0.83

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.93
     DUF2774  9 lhesg.knFveIAkkldir 26
                 he+g +n+v I +++  r
  EEA21287.1 22 VHEQGpNNWVRISQQMHFR 40
                3888845799999998765 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 1.2e-05
     DUF2774   5 qvhfl.hesgknFveIAkkldirakdvaklwve 36 
                 ++  + +e+gk + eIA++l+ r  ++ k w +
  EEA21287.1  69 MIERMvNEMGKRWAEIARRLGNRSDNAVKNWWN 101
                 5556779*********************99976 PP

>> SLIDE  SLIDE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   2.6e-05     0.094      49      79 ..       7      37 ..       1      46 [. 0.85
   2 ?   -2.1   0.0         1   3.7e+03      53      78 ..      63      87 ..      40      95 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.6e-05
       SLIDE 49 kkeyteeeDrfllvllakyGygnyekikkei 79
                +  + +eeD+ ll+l+++ G +n+ +i +++
  EEA21287.1  7 RGPWVQEEDNTLLQLVHEQGPNNWVRISQQM 37
                34599**********************9986 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1
       SLIDE 53 teeeDrfllvllakyGygnyekikke 78
                + ee  ++  +++++G + + +i ++
  EEA21287.1 63 SAEEGLMIERMVNEMGKR-WAEIARR 87
                566666777777777754.6666655 PP

>> DUF3701  Phage integrase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.1   8.6e-05      0.31      41      72 ..      72     103 ..      49     123 .. 0.85
   2 ?   -2.1   0.0       1.1   4.1e+03      43      57 ..     242     256 ..     236     259 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 8.6e-05
     DUF3701  41 arinrrgkrWwravprlGaakArrieafLaah 72 
                  ++n +gkrW +  +rlG+ + ++++++ + +
  EEA21287.1  72 RMVNEMGKRWAEIARRLGNRSDNAVKNWWNGN 103
                 579*************************8754 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.1
     DUF3701  43 inrrgkrWwravprl 57 
                 i++r+ +W+++ +r 
  EEA21287.1 242 IDSRQASWYSEQQRR 256
                 8899999*9987665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (320 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       601  (0.0335211); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 2144.55
//
Query:       EEA21288.1  [L=463]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-21   75.6   0.1    3.5e-21   74.8   0.1    1.4  1  NCBP3     Nuclear cap-binding protein subunit 3


Domain annotation for each model (and alignments):
>> NCBP3  Nuclear cap-binding protein subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.8   0.1   1.9e-25   3.5e-21       3      58 ..      67     122 ..      65     123 .. 0.97

  Alignments for each domain:
  == domain 1  score: 74.8 bits;  conditional E-value: 1.9e-25
       NCBP3   3 pealhirGvdnLstedikaYvdeylnyeepfriEWIdDtsvnvvFkseedaakALk 58 
                  e++hirGvd+++t+ ik+++ +y++ ee +riEWIdDts+n v++s+e  ++AL+
  EEA21288.1  67 YEKVHIRGVDEMTTDHIKQFALSYFPDEEASRIEWIDDTSANMVYSSNEVGLRALT 122
                 69*****************************************************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (463 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       423  (0.0235931); expected 358.6 (0.02)
Passed bias filter:                      250  (0.0139439); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.47
# Mc/sec: 2992.48
//
Query:       EEA21289.1  [L=491]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
     0.0044   17.8   2.3        3.9    8.5   0.1    4.4  4  WD40         WD domain, G-beta repeat
  ------ inclusion threshold ------
      0.013   15.8   0.3        0.3   11.4   0.0    2.7  3  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
      0.034   14.1   0.0      0.086   12.8   0.0    1.7  1  LisH         LisH
      0.089   12.1   0.0       0.15   11.4   0.0    1.3  1  WD40_like    WD40-like domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0     0.032   1.5e+02      15      38 .]     131     154 ..     120     154 .. 0.79
   2 ?    1.9   0.0      0.11   4.8e+02      19      37 ..     221     239 ..     206     240 .. 0.82
   3 ?   -1.3   0.0       1.1   4.8e+03      20      35 ..     419     432 ..     403     432 .. 0.76
   4 !    8.5   0.1   0.00088       3.9       9      38 .]     448     486 ..     439     486 .. 0.73

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.032
                 EEEEETTSSEEEEEETTSEEEEEE CS
        WD40  15 slafspdgawlasGsdDgtvriWd 38 
                 ++++s+ g++l++ + D+ + +++
  EEA21289.1 131 DQDNSQRGSYLVATGADRRLNLFN 154
                 6778999999875455**999876 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.11
                 ETTSSEEEEEETTSEEEEE CS
        WD40  19 spdgawlasGsdDgtvriW 37 
                 ++++ w+++ ++D  v i+
  EEA21289.1 221 HDENIWVVTVGWDMQVLIY 239
                 67889**********9997 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 1.1
                 TTSSEEEEEETTSEEE CS
        WD40  20 pdgawlasGsdDgtvr 35 
                  +g w+  G+ Dg +r
  EEA21289.1 419 GSGVWV-NGD-DGVIR 432
                 456674.777.99998 PP

  == domain 4  score: 8.5 bits;  conditional E-value: 0.00088
                 SS..SS.EEEEE......EETTSSEEEEEETTSEEEEEE CS
        WD40   9 GH..ss.vtsla......fspdgawlasGsdDgtvriWd 38 
                 GH  +s v+s+        ++   w++sG+ D+ + +W+
  EEA21289.1 448 GHeaGSkVRSIWagwvegKNSTEEWVVSGGFDKRLIVWK 486
                 7874336888877777777777889****99*******6 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       1.7   7.8e+03      49      76 ..     137     164 ..     135     178 .. 0.79
   2 ?    1.2   0.1       0.1   4.7e+02      21      56 ..     195     228 ..     181     241 .. 0.75
   3 ?   11.4   0.0   6.6e-05       0.3      43      81 ..     412     450 ..     396     464 .. 0.86

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1.7
  ANAPC4_WD40  49 dgklLavaysdgevrlldaesgkvvhsl 76 
                   g+ L+   +d +++l++    ++v ++
   EEA21289.1 137 RGSYLVATGADRRLNLFNLDANNTVATS 164
                  6888899999999999998888877665 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.1
  ANAPC4_WD40  21 vfRlngqrvwtleedkedsevrsLaWkpdgklLava 56 
                  +  ++g++v +  +d+++  v+ La+++ ++ + v+
   EEA21289.1 195 L--VSGNEVIDRRKDHKKYAVKVLAYEEHDENIWVV 228
                  4..578899999999999999999998877666554 PP

  == domain 3  score: 11.4 bits;  conditional E-value: 6.6e-05
  ANAPC4_WD40  43 sLaWkpdgklLavaysdgevrlldaesgkvvhslsvkse 81 
                  ++ W+pdg+   v  +dg +r +++++gk+v  l+ ++e
   EEA21289.1 412 QVVWRPDGSGVWVNGDDGVIRGIESKTGKLVAMLKNGHE 450
                  688****************************99988766 PP

>> LisH  LisH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   1.9e-05     0.086       6      27 .]      23      44 ..      22      44 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.9e-05
                HHHHHHHHCT-HHHHHHHHHHT CS
        LisH  6 LIydYLvkeGyeetAeaFekEa 27
                L+ ++L+ ++y+et   F +Ea
  EEA21289.1 23 LVARFLRSNNYHETLDIFIREA 44
                9***************998887 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   3.3e-05      0.15       7      80 ..     133     206 ..     131     230 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 3.3e-05
   WD40_like   7 diskkgslilyGgkddkctvlklesl.esvsivesfedS.vifvklldddlilvvtlDGtillslleneeevenek 80 
                 d s++gs+++  g d ++ +++l+ + ++ +++ +++dS ++    + ++  l +t+ G++   l++ +e+++ +k
  EEA21289.1 133 DNSQRGSYLVATGADRRLNLFNLDANnTVATSISGLTDSpILSYASIRGQYQLLTTMSGQL--LLVSGNEVIDRRK 206
                 67999******************966156699*******4445578***************..6666666777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (491 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       410  (0.022868); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.56u 0.31s 00:00:00.87 Elapsed: 00:00:00.49
# Mc/sec: 2997.64
//
Query:       EEA21290.1  [L=165]
Description: ATP synthase delta chain, mitochondrial precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.3e-17   62.1   0.0      5e-17   61.6   0.0    1.3  1  ATP-synt_DE_N  ATP synthase, Delta/Epsilon chain, beta-sandwi


Domain annotation for each model (and alignments):
>> ATP-synt_DE_N  ATP synthase, Delta/Epsilon chain, beta-sandwich domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.6   0.0   2.8e-21     5e-17       2      76 ..      36     112 ..      35     116 .. 0.90

  Alignments for each domain:
  == domain 1  score: 61.6 bits;  conditional E-value: 2.8e-21
                    EEEEEESSSEEEEEE.EEEEEEEESSSEEEE-TT--SEEEEEESEEEEEEEGGGEEEEEEESSEEEEEE.TTEEEEE CS
  ATP-synt_DE_N   2 kleivtpervvfsge.veevvaptteGelgilpgHaplitaLkpgelriktedgeeesiavsgGflevq.dnkvtil 76 
                    kl++  p + +f+ + v +v +p+++Ge+gil++H+p i +Lkpg +++ +e g+++ +++sgGf+ vq d++++i 
     EEA21290.1  36 KLSLAMPHQNLFKSTdVVQVNIPAESGEMGILANHVPSIEQLKPGLVEVIEESGSTKQFFLSGGFAVVQpDSRLSIN 112
                    7888899999998888*****************************************************44566665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (165 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       435  (0.0242624); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.23s 00:00:00.62 Elapsed: 00:00:00.39
# Mc/sec: 1284.09
//
Query:       EEA21291.1  [L=190]
Description: ATP synthase delta chain, mitochondrial precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.6e-17   61.7   0.0    6.9e-17   61.1   0.0    1.3  1  ATP-synt_DE_N  ATP synthase, Delta/Epsilon chain, beta-sandwi


Domain annotation for each model (and alignments):
>> ATP-synt_DE_N  ATP synthase, Delta/Epsilon chain, beta-sandwich domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.1   0.0   3.9e-21   6.9e-17       2      76 ..      36     112 ..      35     116 .. 0.89

  Alignments for each domain:
  == domain 1  score: 61.1 bits;  conditional E-value: 3.9e-21
                    EEEEEESSSEEEEEE.EEEEEEEESSSEEEE-TT--SEEEEEESEEEEEEEGGGEEEEEEESSEEEEEE.TTEEEEE CS
  ATP-synt_DE_N   2 kleivtpervvfsge.veevvaptteGelgilpgHaplitaLkpgelriktedgeeesiavsgGflevq.dnkvtil 76 
                    kl++  p + +f+ + v +v +p+++Ge+gil++H+p i +Lkpg +++ +e g+++ +++sgGf+ vq d++++i 
     EEA21291.1  36 KLSLAMPHQNLFKSTdVVQVNIPAESGEMGILANHVPSIEQLKPGLVEVIEESGSTKQFFLSGGFAVVQpDSRLSIN 112
                    7888899999998888*****************************************************44566665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (190 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       338  (0.0188521); expected 358.6 (0.02)
Passed bias filter:                      299  (0.0166769); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.30s 00:00:00.84 Elapsed: 00:00:00.51
# Mc/sec: 1114.01
//
Query:       EEA21292.1  [L=65]
Description: 60S ribosomal protein L29, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.2e-22   79.1   9.0    3.7e-22   78.4   9.0    1.4  1  Ribosomal_L29e  Ribosomal L29e protein family


Domain annotation for each model (and alignments):
>> Ribosomal_L29e  Ribosomal L29e protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.4   9.0   2.1e-26   3.7e-22       1      40 []       3      42 ..       3      42 .. 1.00

  Alignments for each domain:
  == domain 1  score: 78.4 bits;  conditional E-value: 2.1e-26
  Ribosomal_L29e  1 KsKNhTnHNqsrKaHRNGIKkpksqrykslkgvdpkflrN 40
                    KsKN ++HNqs+KaHRNGIKkpk+ ry+slkg+dpkf+rN
      EEA21292.1  3 KSKNSSQHNQSKKAHRNGIKKPKTYRYPSLKGTDPKFRRN 42
                    9*************************************** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (65 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      196  (0.010932); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.37u 0.28s 00:00:00.65 Elapsed: 00:00:00.44
# Mc/sec: 448.18
//
Query:       EEA21293.1  [L=362]
Description: pyridoxal kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.5e-11   41.7   0.0    1.4e-10   41.0   0.0    1.4  1  Phos_pyr_kin  Phosphomethylpyrimidine kinase
    9.8e-06   25.1   0.9    5.6e-05   22.6   0.9    2.3  1  PfkB          pfkB family carbohydrate kinase
  ------ inclusion threshold ------
      0.081   12.1   0.0       0.12   11.6   0.0    1.2  1  FBPase_3      Fructose-1,6-bisphosphatase
       0.22   11.4   0.4       0.47   10.4   0.4    1.5  1  Mago-bind     Mago binding


Domain annotation for each model (and alignments):
>> Phos_pyr_kin  Phosphomethylpyrimidine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.0   0.0   3.1e-14   1.4e-10      86     214 ..     119     255 ..      32     273 .. 0.69

  Alignments for each domain:
  == domain 1  score: 41.0 bits;  conditional E-value: 3.1e-14
                   TSSEEEE---SSCTSSSBSSHHHHHHHHHHTGGG-SEEE-BHHHHHHHHT---SSHHHHHHHHHHHHH.TT-SEEEEEEGGS-S........SSEEE CS
  Phos_pyr_kin  86 kvpvVlDPVmvaksgselleeeavealkeeLlplatvitPNlpEaeaLlgekikteedmkeaakkllk.lgakaVlikGghleg........eeavv 173
                   ++  +lDPVm  + g+  ++e++v a+k+  +++a++i PN +E+e L+g ki++++d+ +a + ++k +g+ +++++  +l++          +v+
    EEA21293.1 119 SFFWILDPVMG-DLGRLYVAEDVVPAYKK-TVHHADLILPNQFETEILSGIKISNTTDLANAITIIHKtYGVPHIIVTSVQLSNlgsstpsgLMTVI 213
                   2368*****95.7899999999*****98.9999**********************************99***********9777877665423333 PP

                   EEEEETSSEE..EEEEEE----S--BTHHHHHHHHHHHHHHCT CS
  Phos_pyr_kin 174 tdvlydgeev..eeleaerietknthGtGCtlssaiaaelakg 214
                     ++ ++++   ++++ + +e  n +GtG+ +++   a+l + 
    EEA21293.1 214 GSTVRSDGSPrlFHVDIPALE-CNFNGTGDMFAALTVARLREA 255
                   333335554401444555666.899*********999998654 PP

>> PfkB  pfkB family carbohydrate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.6   0.9   1.2e-08   5.6e-05     173     268 ..     140     251 ..      19     264 .. 0.80

  Alignments for each domain:
  == domain 1  score: 22.6 bits;  conditional E-value: 1.2e-08
                 HHHHHHHHHCTESEEEEEHHHHHHHHTSCT...HSHHHHHHHHHHHHHTTSSEEEEEEGGGEEEEEE................TTEEEEEEE.SSSS-S CS
        PfkB 173 fkeallellaladllkpneeElealtgekl...edieealaalhklkakgaktvvvtlGkeGalvve................kdgelkvpavpkvkvv 252
                 +++a+++ + +adl+ pn+ E e+l+g k+   +d ++a+  +hk  + g+ +++vt      l ++                ++  l++  +p     
  EEA21293.1 140 VVPAYKKTVHHADLILPNQFETEILSGIKIsntTDLANAITIIHK--TYGVPHIIVTSVQLSNLGSStpsglmtvigstvrsdGSPRLFHVDIP-ALEC 235
                 7899**************************777777777777777..6677*****96443333333333666777777766644555555534.5556 PP

                 BGTTHHHHHHHHHHHH CS
        PfkB 253 DttGAGDsfvggflaa 268
                 + +G+GD+f++  +a 
  EEA21293.1 236 NFNGTGDMFAALTVAR 251
                 7777777777766555 PP

>> FBPase_3  Fructose-1,6-bisphosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   2.6e-05      0.12     248     347 ..     181     283 ..     167     296 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 2.6e-05
    FBPase_3 248 evlepfalphlvaGwmrGshngplmPvslkda..kptrfdgpprvvalgfqlkegklvgpvDlfddpafdeaRekaaeiadelRr.qGpfephrlpeee 343
                  + +++ +ph++   ++ s  g+  P  l +   +++r dg pr++ +     e+++ g  D+f+  +  + Re +  +  +lR+ + +++p  +++ e
  EEA21293.1 181 IIHKTYGVPHIIVTSVQLSNLGSSTPSGLMTVigSTVRSDGSPRLFHVDIPALECNFNGTGDMFAALTVARLREAVYATGPTLRNtKSWVSPDDVSPTE 279
                 567889999****9***9****99999988752256899********************************************9724677888887777 PP

    FBPase_3 344 leYt 347
                 l  +
  EEA21293.1 280 LPLA 283
                 7655 PP

>> Mago-bind  Mago binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.4    0.0001      0.47       3      16 ..     211     224 ..     210     224 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.0001
   Mago-bind   3 riIpaSqRpDGtvR 16 
                 ++I +++R+DG+ R
  EEA21293.1 211 TVIGSTVRSDGSPR 224
                 69**********77 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (362 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       415  (0.0231469); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.49u 0.31s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2449.21
//
Query:       EEA21294.1  [L=207]
Description: dUTPase (Dut), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.4e-44  148.6   0.0    9.5e-44  148.2   0.0    1.1  1  dUTPase   dUTPase
  ------ inclusion threshold ------
      0.024   13.4   0.0      0.034   12.9   0.0    1.1  1  DCD       2'-deoxycytidine 5'-triphosphate deaminase (DCD)


Domain annotation for each model (and alignments):
>> dUTPase  dUTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  148.2   0.0   1.1e-47   9.5e-44       2     129 .]      78     206 ..      77     206 .. 0.98

  Alignments for each domain:
  == domain 1  score: 148.2 bits;  conditional E-value: 1.1e-47
                 TCTBEBESSTT-SSEEEE-SSSEEEETTEEEEEEEEEEEE--TTEEEEEEE-HHHHHHHEEEEE.EEEETTBTSEEEEEEEE-SSS-EEE-TT-EEEEE CS
     dUTPase   2 eaeiptrkspesAgyDlsaakdltvkpgetvlvptdisiklpdglaalilpRSglaakglivvp.gvidsdyrGevkvvlfnltkkdvkikkgdRiAqL 99 
                 +a++ptr+s+ +AgyDl++ak+++++++++ +v t+++i++p+g++++++pRSgla k++i+++ gvid+dyrGevkv lfn+++ d+++k+gdRiAqL
  EEA21294.1  78 SAKAPTRGSAFAAGYDLYSAKETVIPAKGKGMVDTGLAIAVPEGTYGRVAPRSGLASKNFIDTGaGVIDADYRGEVKVLLFNFSDVDFTVKEGDRIAQL 176
                 5789*********************************************************************************************** PP

                 EEEEBECGEEEEESSTTTESSBTTXTTTTX CS
     dUTPase 100 ifariltaeleevetlkatergeggfgssg 129
                 +++ri t+ +  ve+l+++ rg ggfgs+g
  EEA21294.1 177 VLERIYTPDVVVVEQLEESVRGAGGFGSTG 206
                 ***************************997 PP

>> DCD  2'-deoxycytidine 5'-triphosphate deaminase (DCD)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   3.8e-06     0.034     289     335 ..     137     183 ..     132     195 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 3.8e-06
         DCD 289 ffDpGFGlaeaggegsravLevRsrevPFiledgqivgrlvyermae 335
                 f+D+G G+ +a+ +g   vL     +v F +++g  +++lv+er+ +
  EEA21294.1 137 FIDTGAGVIDADYRGEVKVLLFNFSDVDFTVKEGDRIAQLVLERIYT 183
                 99*****************************************9975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (207 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       408  (0.0227564); expected 358.6 (0.02)
Passed bias filter:                      352  (0.019633); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.24s 00:00:00.65 Elapsed: 00:00:00.40
# Mc/sec: 1537.71
//
Query:       EEA21295.1  [L=361]
Description: Phosphotransferase enzyme family domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.5e-45  156.0   0.0    2.5e-45  155.3   0.0    1.4  1  APH             Phosphotransferase enzyme family
    5.8e-07   29.3   0.0      9e-07   28.7   0.0    1.3  1  Choline_kinase  Choline/ethanolamine kinase
    0.00031   20.4   0.0     0.0023   17.6   0.0    2.0  2  RIO1            RIO1 family
    0.00082   18.8   0.0     0.0012   18.2   0.0    1.3  1  EcKinase        Ecdysteroid kinase
     0.0022   16.9   0.0      0.053   12.4   0.0    2.1  1  DUF1679         Protein of unknown function (DUF1679)
  ------ inclusion threshold ------
      0.021   14.2   0.0      0.078   12.3   0.0    1.8  2  Kdo             Lipopolysaccharide kinase (Kdo/WaaP) family


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  155.3   0.0   8.4e-49   2.5e-45       2     217 ..      31     264 ..      30     298 .. 0.83

  Alignments for each domain:
  == domain 1  score: 155.3 bits;  conditional E-value: 8.4e-49
                 EEEE--.SSCEEEEEEETT.--EEEEEE-TT....S-HHHHHHHHHHHHHHHHTT-B--B-CTTBS-EEETTEEEEEEE----EE-SS....HHHHHHH CS
         APH   2 vrelsggasnrtylvttpa.gryvlrrnppa....raaeeirrevallrlLakagvpvPevlagdtddeeigllfalieyvpgrsllr....klsaaql 91 
                 v++++ g+sn+ty++t+++ ++yv+r +pp+    ++a +++re+++l++L+ ++vpvP+v+ +++d+++ig+ f+++e+++gr +++      sa+++
  EEA21295.1  31 VKQFGFGQSNPTYQLTDATgTKYVMRKKPPGkllsKTAHQVEREYQILHALQPTDVPVPKVYTLCEDGNVIGTAFYIMEFLDGRMITDpaipGVSAEER 129
                 89999**************77**********999999*******************************************************99***** PP

                 HHHHHHHHHHHCCHHCH.-STTTB-SHHCHTCCHHHHHHCHHH......CCCGCCTCC...HHHHHHHHHHHHHHHH--S........SS-EEEE-SS- CS
         APH  92 pellealgeflaalhqvdpaalpladflaqdlellrqlesata......rllaselld...lleeleeqvlaalaallpg........elptvllHgDl 173
                  e++++++++l++lh+vdp + +++ f++++ + +rq+    +      + ++ ++++   +l  + e+v+                  ++t+++HgD+
  EEA21295.1 130 HEIWRDAVRTLGKLHRVDPKSVGMEKFGKHTGFYDRQISTLGRvsqaqaQAVDVDTKEpvgELPYFQENVR--------FfsnkslqpRDRTTFVHGDY 220
                 ******************************99999777666322000023344444444444444444433........344444444899******** PP

                 SGGGEEEC..TTEEEEE---TT-EEEECCHHHHCCHHH.CSCHCC CS
         APH 174 hpgNllvdpddgrvtGviDfedaglgpplyDlavllrs.wtseld 217
                 + +Nl+++++++rv+G++D+e+a++g+pl D+a l  s w  +  
  EEA21295.1 221 KIDNLVFHKTEPRVIGILDWEMATIGHPLSDIANLT-SpWFLDSA 264
                 **********************************99.54764444 PP

>> Choline_kinase  Choline/ethanolamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.7   0.0     3e-10     9e-07      17     210 ..      68     279 ..      51     282 .. 0.73

  Alignments for each domain:
  == domain 1  score: 28.7 bits;  conditional E-value: 3e-10
                     CCHHHHHHHHHHHHHHTTS.SS-EEEEETTEEEE.......E--TCEE--TTGG......GCHHHHHHHHHHHHHHTTCHH.....TTSSSS-HH CS
  Choline_kinase  17 lidretElvvfallsergl.gpklygifenGrie.......efiesrtlstedl......repeiskkiAkklaelHslel....eseskespsl 93 
                     + ++e+E ++++ l+  ++  pk+y + e+G +        ef+++r+++   +      + +ei++   + l++lH++++    ++   +++  
      EEA21295.1  68 AHQVEREYQILHALQPTDVpVPKVYTLCEDGNVIgtafyimEFLDGRMITDPAIpgvsaeERHEIWRDAVRTLGKLHRVDPksvgMEKFGKHTGF 162
                     55677777777777777663477777777776433444445888888888776644444346789999999**********44442222222222 PP

                     HHHHHHH.....HHCCS.TT..ECHHGGCCHCCCTHHHHHHHHHTHHHHHHCHGG-EEEE-S--SGGGEEE.-CTTEEE.E--GTT-EEEEHHHH CS
  Choline_kinase  94 wktmqkw.....llnkeaqtkakkekkkkqlklinledlekelekleklleelespvvfcHnDlqegNillnkeekklv.lIDFEYagynyrgfD 182
                           +     +l  ++q +a+ +  +++    +l  +++ +  + +   + +   +f H D    N++++k+e++++ + D+E a++     D
      EEA21295.1 163 ------YdrqisTLGRVSQAQAQAVDVDTKEPVGELPYFQENVRFFSNKSLQPRDRTTFVHGDYKIDNLVFHKTEPRVIgILDWEMATIGHPLSD 251
                     ......23334456777888888888888888888888888888888888788999***************99999988477************* PP

                     HHHHHHHTTEEHHHCSTSHEE-GGGS-- CS
  Choline_kinase 183 lanhfiEwagdyeeeeaffkldyskyps 210
                     +an  + w +d+ e++a++  ++  +p+
      EEA21295.1 252 IANLTSPWFLDSAEHKAEHFQQSLGMPT 279
                     ***********99999955555555555 PP

>> RIO1  RIO1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   7.6e-07    0.0023      49     118 ..      65     140 ..      45     146 .. 0.79
   2 ?   -0.0   0.0      0.19   5.7e+02     125     147 ..     213     235 ..     200     250 .. 0.83

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 7.6e-07
                 HHHHHHHHHHHHHHHHHHHTT--S--EEEEET..TEE.....EEE--EETTEEGGBHHHCG-HHHHHHHHHHHHHHH CS
        RIO1  49 klvklwaekEfrnLkrleeagvpvPkpielkr..hvl.....vmefigedgvaapklkdveeeeeaeelyeevleem 118
                 + +   +e+E+++L++l+ ++vpvPk+++l +  +v+     +mef++ + +  p +  v+  ee +e+ ++ ++++
  EEA21295.1  65 SKTAHQVEREYQILHALQPTDVPVPKVYTLCEdgNVIgtafyIMEFLDGRMITDPAIPGVS-AEERHEIWRDAVRTL 140
                 5566789*********************985433676666669*****9999999999999.777888888887765 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 0.19
                 STEEESS-STTSEEEETTEEEE- CS
        RIO1 125 aglvHaDLSeyNvlvdedkvviI 147
                  + vH+D    N+++++ ++ +I
  EEA21295.1 213 TTFVHGDYKIDNLVFHKTEPRVI 235
                 678*********99999987766 PP

>> EcKinase  Ecdysteroid kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0   4.1e-07    0.0012     198     260 ..     193     255 ..     142     275 .. 0.76

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 4.1e-07
    EcKinase 198 nlferllelve...ekeeefnvlnHGDlwvnNimfkydeegepedvilvDFQlsrygSpalDLlyf 260
                  +f++ +++++    ++ + ++++HGD+ + N+ f+ +   ep  + ++D+ ++ +g p  D++ +
  EEA21295.1 193 PYFQENVRFFSnksLQPRDRTTFVHGDYKIDNLVFHKT---EPRVIGILDWEMATIGHPLSDIANL 255
                 477777777776666888999**************775...7999*****************9865 PP

>> DUF1679  Protein of unknown function (DUF1679)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.4   0.0   1.8e-05     0.053     111     314 ..      67     256 ..      61     273 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 1.8e-05
     DUF1679 111 elHNrEvelYkileklnheeilltkvyflkkfdeenklkgyiimeyvedihtls.myenikadelipvlk.aiAtlqalslslseeekksasgadflee 207
                 ++H  E   Y+il+ l++ +++++kvy l + d +    ++ ime++++  ++  +   ++a+e + + + a+ tl  l     + + ks+  ++f   
  EEA21295.1  67 TAHQVER-EYQILHALQPTDVPVPKVYTLCE-DGNVIGTAFYIMEFLDGRMITDpAIPGVSAEERHEIWRdAVRTLGKL----HRVDPKSVGMEKF--G 157
                 5666664.499****************9975.55556689999****99776651567899999999986255555433....3445666656666..4 PP

     DUF1679 208 vleellseeelkkifeqlrkilgaeeeekveelvdiveeylkeililekaskvskvlGikkvlvhgDlwsaNiLfseeeegklklkkviDyQlvslgnp 306
                     +++  +++    ++ ++++++ +   +e v  +  +    +++  +s+ s     +  +vhgD    N++f++ e     +  ++D+ ++++g p
  EEA21295.1 158 KHTGFYDR-QISTL-GRVSQAQAQAVDVDTKEPVGELPYF---QENVRFFSNKSLQPRDRTTFVHGDYKIDNLVFHKTEP---RVIGILDWEMATIGHP 248
                 44556665.44433.3333444455666666777766666...3344444443333334889999999999999999555...7889999999999999 PP

     DUF1679 307 aeDlvrll 314
                   D++ l 
  EEA21295.1 249 LSDIANLT 256
                 99999875 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   2.6e-05     0.078      58     137 ..      71     146 ..      62     150 .. 0.83
   2 ?   -1.9   0.0      0.61   1.8e+03     138     167 ..     214     241 ..     211     244 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 2.6e-05
         Kdo  58 avrEfrllkrLeeagvavpkpvaagavkvgleyrAlllterlegaqdLedllakwaelaeelkrallkavgrliaklhra 137
                 + rE+++l++L+   v+vpk  +  ++  ++  +A+ ++e l+g    +  +     ++ e +++++++  r+  klhr+
  EEA21295.1  71 VEREYQILHALQPTDVPVPKV-YTLCEDGNVIGTAFYIMEFLDGRMITDPAIPG---VSAEERHEIWRDAVRTLGKLHRV 146
                 679****************96.555666778889**********7755555554...88999999*************97 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.61
         Kdo 138 gvnHadlyaknillqqeeeeeaeiwliDld 167
                    H+d  + n+ ++++e   + i ++D +
  EEA21295.1 214 TFVHGDYKIDNLVFHKTE--PRVIGILDWE 241
                 5679*******9999997..7777777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (361 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       361  (0.020135); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.49u 0.21s 00:00:00.70 Elapsed: 00:00:00.38
# Mc/sec: 2880.01
//
Query:       EEA21296.1  [L=565]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.2e-06   28.6  11.0     0.0091   16.4   2.6    3.9  3  zf-C2H2    Zinc finger, C2H2 type
     0.0083   16.5  18.2        0.8   10.2   0.2    5.3  5  zf-H2C2_2  Zinc-finger double domain
  ------ inclusion threshold ------
      0.022   15.6  10.3       0.17   12.8   2.2    3.7  3  zf-C2H2_4  C2H2-type zinc finger
      0.049   13.9   6.0       0.21   11.9   1.1    2.4  2  zf-Di19    Drought induced 19 protein (Di19), zinc-binding


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.0   0.1   0.00045         2       1      23 []     443     468 ..     443     468 .. 0.96
   2 !    6.8   0.1    0.0023        10       3      23 .]     476     503 ..     474     503 .. 0.86
   3 !   16.4   2.6     2e-06    0.0091       1      23 []     508     533 ..     508     534 .. 0.96

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00045
                 EEET..TTT.EEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCp..dCg.ksFkrksnLkrHirtH 23 
                 ykC+  +C+   F ++++L++H ++H
  EEA21296.1 443 YKCSypGCTaGAFQTQYLLNSHANVH 468
                 899999***99************999 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.0023
                 ET..TTT.....EEESSHHHHHHHHHCC CS
     zf-C2H2   3 Cp..dCg.....ksFkrksnLkrHirtH 23 
                 Cp  +C+     k Fkrk ++ rH  +H
  EEA21296.1 476 CPvaGCPrgiggKGFKRKNEMIRHGLVH 503
                 888888888888************8888 PP

  == domain 3  score: 16.4 bits;  conditional E-value: 2e-06
                 EEETTTT...EEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCpdCg...ksFkrksnLkrHirtH 23 
                 y+Cp C+    +++r++nL+rH r+H
  EEA21296.1 508 YVCPFCTdqqHKYPRPDNLQRHVRVH 533
                 99***********************6 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   1.0     0.072   3.2e+02       4      14 ..     144     154 ..     144     156 .. 0.93
   2 ?   -0.7   0.1       0.5   2.3e+03      11      19 ..     439     447 ..     431     451 .. 0.78
   3 !    8.7   0.1   0.00055       2.5       2      19 ..     461     478 ..     461     491 .. 0.86
   4 ?    4.5   0.1     0.012        53      13      21 ..     505     514 ..     497     516 .. 0.78
   5 !   10.2   0.2   0.00018       0.8       1      13 [.     525     537 ..     525     543 .. 0.91

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.072
   zf-H2C2_2   4 rHirkHtgekp 14 
                 +H r H+++kp
  EEA21296.1 144 KHRRLHRKPKP 154
                 7*********8 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.5
   zf-H2C2_2  11 gekpyeCpl 19 
                 g++ y+C++
  EEA21296.1 439 GPSMYKCSY 447
                 8999***85 PP

  == domain 3  score: 8.7 bits;  conditional E-value: 0.00055
   zf-H2C2_2   2 LrrHirkHtgekpyeCpl 19 
                 L+ H  +H +++p+ Cp+
  EEA21296.1 461 LNSHANVHSQDRPHFCPV 478
                 899**************4 PP

  == domain 4  score: 4.5 bits;  conditional E-value: 0.012
   zf-H2C2_2  13 kp.yeCplCd 21 
                 +p y Cp+C 
  EEA21296.1 505 SPgYVCPFCT 514
                 4559*****7 PP

  == domain 5  score: 10.2 bits;  conditional E-value: 0.00018
   zf-H2C2_2   1 nLrrHirkHtgek 13 
                 nL+rH r+H+++k
  EEA21296.1 525 NLQRHVRVHHVDK 537
                 8*********987 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.1     0.012        52       1      23 [.     443     468 ..     443     469 .. 0.89
   2 ?    1.0   0.1      0.23     1e+03       7      19 ..     487     499 ..     474     503 .. 0.81
   3 ?   12.8   2.2   3.8e-05      0.17       1      24 []     508     534 ..     508     534 .. 0.92

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.012
   zf-C2H2_4   1 fkCpi..C.gksFsskkaLlrHlkth 23 
                 +kC++  C  + F +++ L++H + h
  EEA21296.1 443 YKCSYpgCtAGAFQTQYLLNSHANVH 468
                 89******9999999999999*9888 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.23
   zf-C2H2_4   7 gksFsskkaLlrH 19 
                 gk F++k+++ rH
  EEA21296.1 487 GKGFKRKNEMIRH 499
                 899*******999 PP

  == domain 3  score: 12.8 bits;  conditional E-value: 3.8e-05
   zf-C2H2_4   1 fkCpiC...gksFsskkaLlrHlkthH 24 
                 + Cp+C   +  ++++++L+rH++ hH
  EEA21296.1 508 YVCPFCtdqQHKYPRPDNLQRHVRVHH 534
                 89*****88888999999********* PP

>> zf-Di19  Drought induced 19 protein (Di19), zinc-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.3     0.011        50       4      37 ..     444     479 ..     441     503 .. 0.66
   2 ?   11.9   1.1   4.8e-05      0.21       3      29 ..     508     538 ..     506     541 .. 0.76

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.011
     zf-Di19   4 tC..PyCgk.eltvkeLveHvedeHrveskevvCPvC 37 
                 +C  P C+  +++++ L++   + H+++ +++ CPv 
  EEA21296.1 444 KCsyPGCTAgAFQTQYLLNSHANVHSQD-RPHFCPVA 479
                 5633569997799888887666668765.789***94 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 4.8e-05
     zf-Di19   3 ftCPyCgk.eltv...keLveHvedeHrves 29 
                 + CP+C++ +++    ++L++Hv ++H ++ 
  EEA21296.1 508 YVCPFCTDqQHKYprpDNLQRHVRVHHVDKD 538
                 68****986676522268*******998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (565 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       418  (0.0233142); expected 358.6 (0.02)
Passed bias filter:                      228  (0.0127168); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.47
# Mc/sec: 3592.63
//
Query:       EEA21297.1  [L=248]
Description: C2H2 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
      3e-06   27.4   7.3     0.0028   18.0   0.1    4.0  3  zf-C2H2    Zinc finger, C2H2 type
    0.00039   21.0   3.9       0.13   12.9   0.1    2.7  2  FOXP-CC    FOXP coiled-coil domain
     0.0018   19.0  12.3       0.13   13.2   0.1    4.1  4  zf-C2H2_4  C2H2-type zinc finger
     0.0051   17.0   7.1      0.043   14.0   0.7    2.5  2  DUF2475    Protein of unknown function (DUF2475)


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.0   1.9   0.00046       2.1       2      23 .]     157     182 ..     156     182 .. 0.90
   2 ?    0.4   0.0      0.24   1.1e+03      10      23 .]     201     214 ..     188     214 .. 0.86
   3 !   18.0   0.1   6.3e-07    0.0028       2      23 .]     219     243 ..     218     243 .. 0.94

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00046
                 EET..TTT..EEESSHHHHHHHHHCC CS
     zf-C2H2   2 kCp..dCg..ksFkrksnLkrHirtH 23 
                 +C   +C+   +F+r  +L++H ++H
  EEA21297.1 157 RCRypGCTskAVFTRACDLRKHFNRH 182
                 67777899999*************99 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.24
                 ESSHHHHHHHHHCC CS
     zf-C2H2  10 FkrksnLkrHirtH 23 
                 F++k +  rH  +H
  EEA21297.1 201 FSSKKDRARHEAKH 214
                 99999999999988 PP

  == domain 3  score: 18.0 bits;  conditional E-value: 6.3e-07
                 EET..TTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   2 kCp..dCgksFkrksnLkrHirt.H 23 
                 +C+  +C+++F+r +n+k H r+ H
  EEA21297.1 219 PCEweGCDRVFSRVDNMKDHVRRiH 243
                 588889*****************99 PP

>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.4   0.7   0.00076       3.4       6      30 ..     157     183 ..     154     189 .. 0.85
   2 !   12.9   0.1   2.9e-05      0.13       7      34 ..     220     247 ..     216     248 .] 0.91

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00076
     FOXP-CC   6 vCkWPgC..ekvledveeflkhlnseH 30 
                  C+ PgC  ++v++ + ++ kh+n++ 
  EEA21297.1 157 RCRYPGCtsKAVFTRACDLRKHFNRHK 183
                 6******887899*********98754 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 2.9e-05
     FOXP-CC   7 CkWPgCekvledveeflkhlnseHaldd 34 
                 C+W gC++v++ v+++  h+++ H  ++
  EEA21297.1 220 CEWEGCDRVFSRVDNMKDHVRRIHVRGS 247
                 *********************9997765 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.1       3.8   1.7e+04       8      19 ..      70      81 ..      69      81 .. 0.75
   2 !    8.7   1.8   0.00081       3.6       2      23 ..     157     182 ..     156     183 .. 0.89
   3 ?    2.5   0.1     0.075   3.4e+02       8      23 ..     199     214 ..     187     215 .. 0.84
   4 !   13.2   0.1   2.9e-05      0.13       2      24 .]     219     243 ..     218     243 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 3.8
   zf-C2H2_4  8 ksFsskkaLlrH 19
                + + +++++++H
  EEA21297.1 70 RHYQNPYTMSSH 81
                677888888888 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.00081
   zf-C2H2_4   2 kCpi..C..gksFsskkaLlrHlkth 23 
                 +C++  C  +++F++ ++L++H+++h
  EEA21297.1 157 RCRYpgCtsKAVFTRACDLRKHFNRH 182
                 68888899999**************9 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.075
   zf-C2H2_4   8 ksFsskkaLlrHlkth 23 
                 + Fsskk+  rH ++h
  EEA21297.1 199 GGFSSKKDRARHEAKH 214
                 5799***9888*9999 PP

  == domain 4  score: 13.2 bits;  conditional E-value: 2.9e-05
   zf-C2H2_4   2 kCpi..CgksFsskkaLlrHlkthH 24 
                 +C++  C+++Fs+ +++++H+++ H
  EEA21297.1 219 PCEWegCDRVFSRVDNMKDHVRRIH 243
                 577788****************988 PP

>> DUF2475  Protein of unknown function (DUF2475)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.0   1.0     0.003        13       9      45 ..      50      84 ..      42      99 .. 0.78
   2 !   14.0   0.7   9.5e-06     0.043       6      34 ..     100     129 ..      96     146 .. 0.82

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.003
     DUF2475  9 rGyvPqvkysfGdtYGnttaklfqDyRsaaleksttr 45
                +GyvP  + s +d +G+++ + +q+    ++++  t 
  EEA21297.1 50 TGYVPANSVSSSDYHGSQSGRHYQN--PYTMSSHPTA 84
                7******************999998..5555555554 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 9.5e-06
     DUF2475   6 PGYrGyvPqvkysfGdtYGnttaklf.qDy 34 
                 P Y Gy+P+ +y+ + +Y ++ + ++ qD+
  EEA21297.1 100 PSYPGYIPESAYQTSMPYPHAQHEYLlQDH 129
                 99*****************99998852663 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (248 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       511  (0.0285013); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.41u 0.25s 00:00:00.65 Elapsed: 00:00:00.39
# Mc/sec: 1907.67
//
Query:       EEA21298.1  [L=289]
Description: L-cystine transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-36  124.0   7.1    1.4e-17   63.2   3.6    2.6  2  PQ-loop   PQ loop repeat


Domain annotation for each model (and alignments):
>> PQ-loop  PQ loop repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.2   3.6   7.6e-22   1.4e-17       1      59 [.      13      71 ..      13      73 .. 0.96
   2 !   61.7   0.1   2.2e-21     4e-17       2      58 ..     168     224 ..     167     227 .. 0.95

  Alignments for each domain:
  == domain 1  score: 63.2 bits;  conditional E-value: 7.6e-22
     PQ-loop  1 lseilgyislvlwlvsyiPQiikNykrkSteGlSilflllwllGdilsllylilngfpp 59
                ls +lg+i++v+w++s++PQ + N +r+St Gl i+f  +++lG+i++++y++ + ++p
  EEA21298.1 13 LSRLLGWIYTVCWSLSFYPQPLNNIRRRSTYGLAIDFPTINTLGFICYAIYCLGFLYSP 71
                6899*************************************************998887 PP

  == domain 2  score: 61.7 bits;  conditional E-value: 2.2e-21
     PQ-loop   2 seilgyislvlwlvsyiPQiikNykrkSteGlSilflllwllGdilsllylilngfp 58 
                  ++++yi++v+++v+y+PQ ++NykrkSt+G+ i  +ll+l+G++lsl++l+l+++ 
  EEA21298.1 168 LYAMSYIKVVITVVKYVPQAWLNYKRKSTTGWDIRQILLDLTGGFLSLAQLVLDSSF 224
                 6899************************************************99875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (289 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       470  (0.0262145); expected 358.6 (0.02)
Passed bias filter:                      306  (0.0170673); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.48
# Mc/sec: 1806.48
//
Query:       EEA21299.1  [L=799]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.9e-07   31.3   8.1      4e-07   30.3   8.1    1.5  1  Cytochrom_B561   Eukaryotic cytochrome b561
  ------ inclusion threshold ------
       0.22   12.0   0.0       0.22   12.0   0.0    4.2  7  DUF202           Domain of unknown function (DUF202)
        7.3    6.7  11.7         26    5.0   7.9    2.9  2  DUF4079          Protein of unknown function (DUF4079)


Domain annotation for each model (and alignments):
>> Cytochrom_B561  Eukaryotic cytochrome b561
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.3   8.1   6.7e-11     4e-07       2     131 ..      67     193 ..      66     196 .. 0.91

  Alignments for each domain:
  == domain 1  score: 30.3 bits;  conditional E-value: 6.7e-11
                     HHHHHHHHHTHHHHHHHTHHHHS-S...-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT--SS-SHHHHHHHHHHHHHHHHHHHHHHHHTS CS
  Cytochrom_B561   2 HpvlmviGfvllmgeaiLvyrvsstrklskktkkllHlilqllalilavvgllavfksknekeianlyslHswlGlvtvilfllqlvlGfvlfll 96 
                     H v+ +i f+ ++  ai++ r   + ++++ +    H++lq+l l+l++v +l+ +        + l++ H  +Gl+  +++++q++ G ++  +
      EEA21299.1  67 HGVIATIVFLGFVPAAIMIVRY--YSFYDRYWAYKYHVWLQVLTLLLSTVVFLLGWFAVG--PQRSLTNPHHGIGLALYVMVVFQAFWGWLSRKI 157
                     99999****************9..5669****************9999887777655544..3589999************************** PP

                     S---HHHHHHHHHH.HHHHHHHHHHHHHHHHHHHHH CS
  Cytochrom_B561  97 pklskklralllpl.HvllGlvifvlaivtallGll 131
                     ++ ++++r+ l ++ H+++G ++ +l+++++ +Gl+
      EEA21299.1 158 ERGRRHYRSPLILVlHRWIGWATVLLGMAQIPMGLT 193
                     *******99999999*******************94 PP

>> DUF202  Domain of unknown function (DUF202)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.1       0.7   4.2e+03      42      62 ..      70      88 ..      53      94 .. 0.58
   2 ?    3.9   2.3     0.012        73      13      61 ..     103     154 ..     101     162 .. 0.80
   3 ?   -3.3   0.1       2.2   1.3e+04      41      53 ..     174     186 ..     166     195 .. 0.61
   4 ?   12.0   0.0   3.7e-05      0.22      18      63 ..     203     278 ..     200     282 .. 0.88
   5 ?   -3.0   0.0       1.8   1.1e+04      19      30 ..     309     320 ..     300     345 .. 0.65
   6 ?   -3.9   0.0         3   1.8e+04      49      56 ..     408     415 ..     396     424 .. 0.54
   7 ?   -1.9   0.0       0.8   4.8e+03      45      64 ..     528     547 ..     503     549 .. 0.56

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.7
      DUF202 42 ilglilivlgiltllvglvry 62
                i+   ++ lg++ +++ +vry
  EEA21299.1 70 IAT--IVFLGFVPAAIMIVRY 88
                333..4444444444444444 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.012
      DUF202  13 WlRtslalialglallrffl......tgepsalgkilglilivlgiltllvglvr 61 
                 Wl ++++l+++ ++ll +f           ++  + +gl+l v+ ++ +++g+ +
  EEA21299.1 103 WLQVLTLLLSTVVFLLGWFAvgpqrsL---TNPHHGIGLALYVMVVFQAFWGWLS 154
                 9***************99997664321...2224788999999999999999975 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 2.2
      DUF202  41 kilglilivlgil 53 
                 +++g++ ++lg++
  EEA21299.1 174 RWIGWATVLLGMA 186
                 5666666666654 PP

  == domain 4  score: 12.0 bits;  conditional E-value: 3.7e-05
      DUF202  18 lalialglallrffl..............................tgepsalgkilglilivlgiltllvglvryl 63 
                 +++++ +++ l++fl                              +  +s++g+++g++++++g+++l+  + r++
  EEA21299.1 203 ILFAVGAFLWLALFLtcsyiydedgvyygpdtdnrgsyvsgpppeERRHSNFGRVAGAAAAGAGLAALFARRNRHH 278
                 6777777777788889***********************9999998899999***************998887776 PP

  == domain 5  score: -3.0 bits;  conditional E-value: 1.8
      DUF202  19 alialglallrf 30 
                 ++i+ g+al+r+
  EEA21299.1 309 GAIGGGIALARS 320
                 455556666653 PP

  == domain 6  score: -3.9 bits;  conditional E-value: 3
      DUF202  49 vlgiltll 56 
                 ++g+++++
  EEA21299.1 408 GAGAFAAV 415
                 23333332 PP

  == domain 7  score: -1.9 bits;  conditional E-value: 0.8
      DUF202  45 lilivlgiltllvglvrylr 64 
                 ++++++ + +++ ++ r++r
  EEA21299.1 528 AAAAGAVAGAAVGSASRHRR 547
                 33333333334444444444 PP

>> DUF4079  Protein of unknown function (DUF4079)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   1.9    0.0059        35      86     136 ..      70     121 ..      44     125 .. 0.81
   2 ?    5.0   7.9    0.0043        26      55     137 ..     102     194 ..      98     198 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.0059
     DUF4079  86 yaGlavvvLlalsaalvpeiqkgks.taRtlHialnvlalllfawqaitGlr 136
                 +a +++++++  ++++v   +  ++ +a + H+ l vl lll +++ + G+ 
  EEA21299.1  70 IATIVFLGFVPAAIMIVRYYSFYDRyWAYKYHVWLQVLTLLLSTVVFLLGWF 121
                 34455677788888888888888888************************96 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.0043
     DUF4079  55 slllllvvlgaigglvllylrrgk..lfpssHlyaGlavvvLlalsa...alvpeiqkgkstaRt.....lHialnvlalllfawqaitGlri 137
                  +l +l +l++++ ++l ++  g    +  +H  +Gla+ v+++++a   +l+ +i++g++  R+     lH  ++ + +ll ++q+++Gl++
  EEA21299.1 102 VWLQVLTLLLSTVVFLLGWFAVGPqrSLTNPHHGIGLALYVMVVFQAfwgWLSRKIERGRRHYRSplilvLHRWIGWATVLLGMAQIPMGLTL 194
                 58888888888888888888877544999**********9999999844469*********9997666669****************999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (799 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1379  (0.0769145); expected 358.6 (0.02)
Passed bias filter:                      514  (0.0286686); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.82u 0.30s 00:00:01.11 Elapsed: 00:00:00.46
# Mc/sec: 5261.41
//
Query:       EEA21300.1  [L=792]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.2e-17   62.5   0.2    7.9e-17   61.2   0.2    1.7  1  Fungal_trans  Fungal specific transcription factor domain
    0.00011   22.3   6.3     0.0002   21.4   6.3    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.2   0.2   8.8e-21   7.9e-17      90     194 ..     322     420 ..     292     473 .. 0.90

  Alignments for each domain:
  == domain 1  score: 61.2 bits;  conditional E-value: 8.8e-21
  Fungal_trans  90 slwilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLP 186
                   + + lq+ l+ + y +  s  +l++ ++++a rl+++lg hr   + g          +    +R++w++++lDk+++l +G+ +++ d++i+lpL 
    EEA21300.1 322 NSENLQAILIGASYAIDISQPSLCWALVSTAARLCQTLGYHRSVGSPG------DNQLDTNLKKRMFWFTYILDKCLSLRMGHSSIMQDFDITLPLS 412
                   4588********************************************......4444488***********************************9 PP

  Fungal_trans 187 cddddlwe 194
                   + + d ++
    EEA21300.1 413 DLSADSQM 420
                   98887765 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   6.3   2.2e-08    0.0002      11      37 ..      20      45 ..      17      48 .. 0.86

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 2.2e-08
                ---STSSSS-HHHHHCTHHHCCCCTCC CS
     Zn_clus 11 vKCdakkPaCsnCkklnleCtfysess 37
                +KCd++ P CsnC+ +nl C+  ++++
  EEA21300.1 20 IKCDKRSP-CSNCRASNLACRTANRPR 45
                8*******.************766655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (792 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       831  (0.0463495); expected 358.6 (0.02)
Passed bias filter:                      517  (0.028836); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.69u 0.30s 00:00:00.99 Elapsed: 00:00:00.47
# Mc/sec: 5115.02
//
Query:       EEA21301.1  [L=333]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (333 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       676  (0.0377043); expected 358.6 (0.02)
Passed bias filter:                      428  (0.0238719); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.30s 00:00:00.80 Elapsed: 00:00:00.47
# Mc/sec: 2123.49
//
Query:       EEA21302.1  [L=798]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-46  158.7   1.2    1.8e-46  157.9   1.2    1.4  1  Afi1      Docking domain of Afi1 for Arf3 in vesicle traffick
    5.2e-37  126.3   0.0    8.3e-37  125.6   0.0    1.3  1  SPA       Stabilization of polarity axis
    2.6e-08   33.0   0.0     0.0036   16.1   0.0    3.4  3  Avl9      Transport protein Avl9
  ------ inclusion threshold ------
      0.013   15.3   4.6      0.028   14.3   4.6    1.4  1  DUF1168   Protein of unknown function (DUF1168)
       0.17   11.5   0.0       0.52    9.8   0.0    1.8  1  DUF2347   Uncharacterized conserved protein (DUF2347)


Domain annotation for each model (and alignments):
>> Afi1  Docking domain of Afi1 for Arf3 in vesicle trafficking
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  157.9   1.2     5e-50   1.8e-46       1     132 [.      88     214 ..      88     215 .. 0.86

  Alignments for each domain:
  == domain 1  score: 157.9 bits;  conditional E-value: 5e-50
        Afi1   1 yilvAeFdidkGpvikhqYPkaipgdetlseLAelmlPdqvhkrkqDitvFfLykdtsteeeeleeeekknklekrkkkksededdvdeedeeeeddne 99 
                 yilvA+F+id+Gp+++hqYP+ai+gde++  LAelmlPdq+h+r+qD+t+FfL+kdt++++e++ e++k+++++k  ++++e e+  dee  ++ed+++
  EEA21302.1  88 YILVASFHIDRGPIMEHQYPAAISGDESM--LAELMLPDQTHVRSQDWTIFFLHKDTESDDEDAGETSKRRRRRK--RQQTETEQGSDEELANDEDLQS 182
                 9****************************..***************************99998865555555555..5555555777788888888888 PP

        Afi1 100 dldelskdeeekagegepllyvlnvvntkkDkt 132
                 d+ + s+d+ee++geg+pl+yvln+vntk+D+t
  EEA21302.1 183 DEPD-STDDEEDSGEGPPLMYVLNLVNTKQDNT 214
                 8877.6777667*******************98 PP

>> SPA  Stabilization of polarity axis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  125.6   0.0   2.3e-40   8.3e-37       2     113 ..     384     493 ..     383     494 .. 0.98

  Alignments for each domain:
  == domain 1  score: 125.6 bits;  conditional E-value: 2.3e-40
         SPA   2 tsllkllekftpeiillinalltskriivlstkasadevsefvLalsnlispagdvlrgfknnsfPyvdlseldalekvpgyIvGvtNPiFeeqeqlWD 100
                 +++l++++ +t++ii+l+na+lt+kr+i+l+++++++ev+e+vLa+++l+s  g++lrgf++++fPy+dl ++d+l kvpg+++GvtNP F+++ ++WD
  EEA21302.1 384 HPHLTTNGAYTHPIIVLVNAMLTQKRVIFLGHNRPSGEVAEAVLAACALAS--GGILRGFTRHAFPYTDLTKIDDLLKVPGFVAGVTNPTFANHPEWWD 480
                 789************************************************..6********************************************* PP

         SPA 101 vlydldsgsvkls 113
                 +l+dl +g++k+s
  EEA21302.1 481 LLCDLPTGRMKIS 493
                 *********9987 PP

>> Avl9  Transport protein Avl9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0     1e-06    0.0036       1      66 [.      86     145 ..      86     168 .. 0.83
   2 ?    2.7   0.0     0.012        42     174     213 ..     393     434 ..     388     445 .. 0.78
   3 !    9.9   0.0   7.2e-05      0.26     268     319 ..     446     494 ..     438     507 .. 0.88

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 1e-06
        Avl9   1 ilailvvgFhHkkGpevefsyppeeeekeekesewklLpflalpDGsHnfeedfvyFtleedeset 66 
                 +++ilv  Fh  +Gp +e+ yp       + + + ++L  l lpD +H  ++d+++F l++d+++ 
  EEA21302.1  86 VEYILVASFHIDRGPIMEHQYP------AAISGDESMLAELMLPDQTHVRSQDWTIFFLHKDTESD 145
                 679*******************......4445555789999******************9777443 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.012
        Avl9 174 frhkvLvlfKlllLekkvlvyg..spveklcelilsliSLip 213
                 + h ++vl+ ++l +k+v++ g  +p  +++e++l+   L +
  EEA21302.1 393 YTHPIIVLVNAMLTQKRVIFLGhnRPSGEVAEAVLAACALAS 434
                 77899***************9854566667777766666655 PP

  == domain 3  score: 9.9 bits;  conditional E-value: 7.2e-05
        Avl9 268 lPYlpLqqldlLsdksvksflvGtsNsLllqqkelladvlvdvdeaeieikd 319
                  PY+ L ++d+L   +v +f++G +N  ++++ e   d+l d+ + +++i++
  EEA21302.1 446 FPYTDLTKIDDL--LKVPGFVAGVTNPTFANHPEW-WDLLCDLPTGRMKISS 494
                 4***********..99***************9999.******9999988875 PP

>> DUF1168  Protein of unknown function (DUF1168)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   4.6   7.7e-06     0.028      67     124 ..     136     193 ..     124     198 .. 0.72

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 7.7e-06
     DUF1168  67 efqqkleenkeeaeektaKkrakRekkkqkakkkkkakkkkkkekekeeksedseeks 124
                  f +k +e ++e+   t+K+r++R+++++++++ ++++ +++++ +++e ++ ++e++
  EEA21302.1 136 FFLHKDTESDDEDAGETSKRRRRRKRQQTETEQGSDEELANDEDLQSDEPDSTDDEED 193
                 589999*********************9777777777777766665555444333333 PP

>> DUF2347  Uncharacterized conserved protein (DUF2347)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0   0.00015      0.52     176     278 ..     397     490 ..     392     495 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00015
     DUF2347 176 ifpLykaaLlrkrILll.ssapveelcslvYllslLssipksleellksessrlrplfnvgvaDipsLekekkesgyiActtdeiLalkkeLyDvlvkl 273
                 i +L  a L++kr+++l ++ p  e+ + v + ++L+s    l  ++       +++ +  ++ i++L k     g++A  t+  +a ++e +D+l +l
  EEA21302.1 397 IIVLVNAMLTQKRVIFLgHNRPSGEVAEAVLAACALASGGI-LRGFT------RHAFPYTDLTKIDDLLKVP---GFVAGVTNPTFANHPEWWDLLCDL 485
                 77899999********9655677888888877777776543.23333......345668899********99...************************ PP

     DUF2347 274 ppkss 278
                 p+  +
  EEA21302.1 486 PTGRM 490
                 98765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (798 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       833  (0.046461); expected 358.6 (0.02)
Passed bias filter:                      608  (0.0339115); expected 358.6 (0.02)
Passed Vit filter:                        87  (0.00485247); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.77u 0.30s 00:00:01.07 Elapsed: 00:00:00.45
# Mc/sec: 5285.10
//
Query:       EEA21303.1  [L=303]
Description: calmodulin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.4e-12   45.2   2.0    4.9e-05   22.9   0.1    2.6  2  EF-hand_6  EF-hand domain
    1.2e-09   37.0   2.3    0.00098   18.5   0.1    2.5  2  EF-hand_1  EF hand
    1.6e-08   34.9   0.2     0.0028   18.1   0.0    2.3  2  EF-hand_7  EF-hand domain pair
    5.5e-05   22.5   4.6     0.0082   15.6   0.4    2.4  2  EF-hand_5  EF hand
    0.00019   21.2   0.7       0.95    9.4   0.0    2.9  3  EF-hand_8  EF-hand domain pair
    0.00032   21.0   0.0        1.3    9.5   0.0    2.4  2  EF-hand_9  EF-hand domain


Domain annotation for each model (and alignments):
>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.3   5.8e-08   0.00017       1      31 []     132     161 ..     132     161 .. 0.94
   2 !   22.9   0.1   1.6e-08   4.9e-05       1      27 [.     202     228 ..     202     235 .. 0.90

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 5.8e-08
   EF-hand_6   1 elreaFklfDkdgdGkidaeElrkalrkalg 31 
                 ++reaF  +D+d+dG ++++++ ++l+ +lg
  EEA21303.1 132 DMREAFLVLDRDNDGNVNRDDVADVLS-NLG 161
                 59************************9.776 PP

  == domain 2  score: 22.9 bits;  conditional E-value: 1.6e-08
   EF-hand_6   1 elreaFklfDkdgdGkidaeElrkalr 27 
                 el  aF +fD d++G++d +Elr+al 
  EEA21303.1 202 ELLNAFAAFDDDDSGQVDVAELRDALL 228
                 5778********************995 PP

>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.4   4.7e-07    0.0014       2      28 ..     133     159 ..     132     160 .. 0.91
   2 !   18.5   0.1   3.3e-07   0.00098       1      26 [.     202     227 ..     202     230 .. 0.91

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 4.7e-07
                 HHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1   2 lkeiFrefDkDgdGkIdfeEfkellkk 28 
                 ++e+F ++D+D+dG +++++  ++l+ 
  EEA21303.1 133 MREAFLVLDRDNDGNVNRDDVADVLSN 159
                 79******************9999875 PP

  == domain 2  score: 18.5 bits;  conditional E-value: 3.3e-07
                 HHHHHHHHHTTTSSSEEEHHHHHHHH CS
   EF-hand_1   1 elkeiFrefDkDgdGkIdfeEfkell 26 
                 el ++F+ fD D +G++d  E++++l
  EEA21303.1 202 ELLNAFAAFDDDDSGQVDVAELRDAL 227
                 6789*******************998 PP

>> EF-hand_7  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   1.1e-05     0.032       3      40 ..     132     165 ..     131     174 .. 0.81
   2 !   18.1   0.0   9.4e-07    0.0028       3      51 ..     202     249 ..     200     255 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.1e-05
   EF-hand_7   3 klkeaFkelDtdgdgyldkeellrllrkifqgagegsk 40 
                 +++eaF  lD+d+dg ++++++ ++l ++    g++ +
  EEA21303.1 132 DMREAFLVLDRDNDGNVNRDDVADVLSNL----GRDPS 165
                 5899**********************986....44444 PP

  == domain 2  score: 18.1 bits;  conditional E-value: 9.4e-07
   EF-hand_7   3 klkeaFkelDtdgdgyldkeellrllrkifqga.gegsklsdeelellfk 51 
                 +l  aF ++D d++g +d++el+++l + +      +s+l+++e++++++
  EEA21303.1 202 ELLNAFAAFDDDDSGQVDVAELRDALLHTN--PdVGESPLTEKEVDEVLN 249
                 68899*******************555332..23999999******9987 PP

>> EF-hand_5  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.4   0.4   0.00053       1.6       2      19 ..     134     151 ..     133     156 .. 0.87
   2 !   15.6   0.4   2.8e-06    0.0082       1      23 [.     204     225 ..     204     228 .. 0.90

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00053
                 HHHHHHH-SS-SSCE-HH CS
   EF-hand_5   2 kdtFqaiDlNgDGkIske 19 
                 +++F  +D ++DG ++++
  EEA21303.1 134 REAFLVLDRDNDGNVNRD 151
                 66799********99987 PP

  == domain 2  score: 15.6 bits;  conditional E-value: 2.8e-06
                 HHHHHHHH-SS-SSCE-HHHHHH CS
   EF-hand_5   1 lkdtFqaiDlNgDGkIskeELkt 23 
                 l++ F a+D + +G++++ EL+ 
  EEA21303.1 204 LNA-FAAFDDDDSGQVDVAELRD 225
                 678.*****************86 PP

>> EF-hand_8  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   0.0   0.00084       2.5      28      51 ..     133     156 ..     114     159 .. 0.81
   2 !    9.2   0.1   0.00034         1      26      54 ..     200     229 ..     185     230 .. 0.74
   3 !    9.4   0.0   0.00032      0.95       2      35 ..     215     251 ..     214     251 .. 0.84

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00084
   EF-hand_8  28 vdilfrefDtdgdGkisfeEFcvl 51 
                 +++ f  +D+d+dG ++ ++  ++
  EEA21303.1 133 MREAFLVLDRDNDGNVNRDDVADV 156
                 45568889**********998765 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00034
   EF-hand_8  26 ee.vdilfrefDtdgdGkisfeEFcvller 54 
                 ++ +   f +fD d++G ++  E  + l +
  EEA21303.1 200 QKeLLNAFAAFDDDDSGQVDVAELRDALLH 229
                 4446677999*************9888766 PP

  == domain 3  score: 9.4 bits;  conditional E-value: 0.00032
   EF-hand_8   2 kgkItreelrrilrilglkk.....glseeevdilfref 35 
                 +g+++++elr++l  l+++       l+e+evd++++ f
  EEA21303.1 215 SGQVDVAELRDAL--LHTNPdvgesPLTEKEVDEVLNGF 251
                 79*********77..5544479999*********99876 PP

>> EF-hand_9  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.5   0.0   0.00042       1.3       3      63 ..     136     191 ..     134     194 .. 0.88
   2 !    9.2   0.0   0.00051       1.5       3      29 ..     206     232 ..     205     247 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00042
   EF-hand_9   3 vFevcDtqktGrVpvsrlidyLravtaqdpeeseLeelakelDPdgedasvdldtflrvmr 63 
                  F v D++  G+V   ++ d+L   +  dp+ s+     +++ P g  ++++l tfl  ++
  EEA21303.1 136 AFLVLDRDNDGNVNRDDVADVLSNLGR-DPSSSAT----AQYFPAGAAQTMNLPTFLSTLS 191
                 4999*********************99.9999875....55569***9********98776 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00051
   EF-hand_9   3 vFevcDtqktGrVpvsrlidyLravta 29 
                  F ++D +  G+V v++l d L ++  
  EEA21303.1 206 AFAAFDDDDSGQVDVAELRDALLHTNP 232
                 49******************9998754 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (303 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       349  (0.0194657); expected 358.6 (0.02)
Passed bias filter:                      244  (0.0136092); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.42u 0.23s 00:00:00.65 Elapsed: 00:00:00.39
# Mc/sec: 2355.91
//
Query:       EEA21304.1  [L=604]
Description: sodium/phosphate symporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.5e-101  339.8  20.8   1.8e-101  339.6  20.8    1.0  1  PHO4      Phosphate transporter family


Domain annotation for each model (and alignments):
>> PHO4  Phosphate transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  339.6  20.8  9.8e-106  1.8e-101       1     336 [.      24     588 ..      24     589 .. 0.97

  Alignments for each domain:
  == domain 1  score: 339.6 bits;  conditional E-value: 9.8e-106
        PHO4   1 iGanDvanafatsvgskaltlrqAvilaaifeflGavllGaeVaetirkgivdvelf..dpselmlgmlaallgaavwlllatvlglPvStthslvGal 97 
                 +GanDvan++atsv+s+++++rqA++l +ife+lGa+++Ga+ a+ti++gi+ v++f  d  + ml++++al++a  w++++t  +  vS+t sl+ a+
  EEA21304.1  24 NGANDVANSWATSVSSRSISYRQAMVLGTIFEMLGAITVGARTADTIKNGIIPVSAFrgDAGVQMLAFTCALAAASSWVMWCTRHSAHVSSTYSLISAV 122
                 8******************************************************999*999************************************* PP

        PHO4  98 iGaalaaeggeavkw.....kklvkivlswvlsPllggiiaallfllvkrlilvk.eklknalralpvlvlvtiailalsilfkge............. 177
                 +G+++a+ g++ v+w     k+l+ i++++ ++P +++++a ++f+l+k ++lv+ ++ k+a+++ p+++l+ +++++lsi++kg+             
  EEA21304.1 123 AGVGVATVGASKVQWgwnggKGLGAIFAGLGMAPAISAAFASIIFMLIKLIVLVRrQPAKWAVWTSPFFFLLAATLCTLSIVYKGSpslglskkpgwyi 221
                 ******9999*****8877769******************************9888****************************999999999999999 PP

        PHO4 178 ................................................................................................... 177
                                                                                                                    
  EEA21304.1 222 aavtmgtgggvcllsaifflpwlhakvikkdptikwwmfifgpllfkrpapaeeheanvpnyavvqdeddktvvgspeinahdveksdqgdastntsek 320
                 999999999****************************************************************************************** PP

        PHO4 178 ................................................................................................... 177
                                                                                                                    
  EEA21304.1 321 dekqlvaaeatqatykelmaqgearfhakllqkrgplgwalrtlrdnpmgagqiyefhnvkilakripamivtgllygihydihaaqtgiagtpdgqrm 419
                 ************************************************************************************************999 PP

        PHO4 178 ......skkddeeteklfkflqvvsaalvsfahGanDvanaiGpllaalisiyk....a.sk.evplwvlllgglaialGlllgGkrviktvGekitkk 264
                       +kk+ +e+e++++f+qv++a+++sfahGanD+ n +Gp+ a+++s+++    a sk +vp+w l++   +i++Gl+++G++++k +G+kit  
  EEA21304.1 420 qrvyshAKKYPNEVEHTYSFIQVITACTASFAHGANDIGNSVGPW-AVIYSAWNtgnaAaSKaPVPVWQLAVLSGCISIGLITYGYNIMKVMGNKITY- 516
                 988865449************************************.9999999999863688899********************************5. PP

        PHO4 265 ltpsrGfaaelaaaltvllasklglPvStThvlvgavvGvGlakkresavnwklvrnivlaWvlTlpvsall 336
                 ++psrG ++e++aaltvl++s++ lPvSt+ +++ga+vGvGl+++  +avnw+ v+ +++aW++T+p+++++
  EEA21304.1 517 HSPSRGSSMEMGAALTVLIFSQYSLPVSTSMCITGATVGVGLCNGTIKAVNWQRVGLLLAAWIMTIPIAGTI 588
                 *********************************************************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (604 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       801  (0.0446762); expected 358.6 (0.02)
Passed bias filter:                      419  (0.02337); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.31s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 4052.87
//
Query:       EEA21305.1  [L=459]
Description: mitotic check point protein (Bub2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    9.6e-28   97.3   0.0    2.4e-23   82.9   0.0    2.1  2  RabGAP-TBC  Rab-GTPase-TBC domain


Domain annotation for each model (and alignments):
>> RabGAP-TBC  Rab-GTPase-TBC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.5   0.0   4.8e-06     0.085      39      83 ..     192     236 ..     167     244 .. 0.78
   2 !   82.9   0.0   1.3e-27   2.4e-23      89     214 ..     290     414 ..     276     415 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 4.8e-06
  RabGAP-TBC  39 ekseeskelsqIkkDvprtfpesesfknkqgqnqLeriLkaysiy 83 
                  ++  s+ + +I++D  rt+ ++  fk + ++ +L r+L+a+++ 
  EEA21305.1 192 VHRGRSPAYTKIRNDTFRTLATDPLFKRRVTEASLIRLLNAVAWK 236
                 4555667799***********99*******************996 PP

  == domain 2  score: 82.9 bits;  conditional E-value: 1.3e-27
  RabGAP-TBC  89 YcqGmndivaplllvsldeeeaFwcfvsLlekyklrdlytsslpglkrklkvleellkkkdpklykhlkeegldlelfaikwfltlflrefpletvlrl 187
                 Y+qGmn ++ap+l    +e eaF +f+ ++ ++ ++ +++  ++g+++ l++++++l+++dpkl+ +l ++g+  el+a++ +ltl++++ pl  vl+l
  EEA21305.1 290 YVQGMNVLCAPFLYAARSEVEAFALFHYFV-TKECPGYVRGAMDGVHKGLRLVDRCLEIVDPKLAAYLFSKGMYAELYAFPSVLTLCACTPPLPEVLHL 387
                 *************7777*************.9***********************************9999**************************** PP

  RabGAP-TBC 188 wD.lllegekfvllrvalailklleeel 214
                 wD l++ g++   + +++a l++ ++ +
  EEA21305.1 388 WDfLFAYGPHL-NILCIVAQLNRMRDAI 414
                 **666689888.6666666666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (459 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       343  (0.019131); expected 358.6 (0.02)
Passed bias filter:                      272  (0.015171); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.24s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 3146.07
//
Query:       EEA21306.1  [L=543]
Description: MYND domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-09   38.3   0.0    5.3e-08   33.4   0.0    2.6  2  SET       SET domain
     0.0034   17.4   5.2     0.0034   17.4   5.2    2.3  2  zf-MYND   MYND finger
  ------ inclusion threshold ------
      0.024   14.8   0.3      0.057   13.6   0.3    1.6  1  TPR_9     Tetratricopeptide repeat
      0.082   12.6   0.6       0.24   11.1   0.6    1.9  1  TPR_11    TPR repeat


Domain annotation for each model (and alignments):
>> SET  SET domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.4   0.0   1.2e-11   5.3e-08       2     155 ..     226     469 ..     225     474 .. 0.68
   2 ?    1.8   0.0     0.063   2.8e+02     158     168 ..     499     509 ..     497     510 .. 0.93

  Alignments for each domain:
  == domain 1  score: 33.4 bits;  conditional E-value: 1.2e-11
                 CEEEESSXBXTTXEEEEEEECCEECHHHHHHHHHH................................................................ CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................................................................ RF
         SET   2 rGvfAtedIpkgeficeypeeiiltkdeadksele................................................................ 36 
                  G+fA++dI++ge+i  + e+++lt ++    +l                                                                 
  EEA21306.1 226 LGLFAKRDIQAGEII--LRESSLLTATNRLHDDLCdacngplpdlsvptekergeravacascddiifcsqkchdeaqetyhgaicgqegldsigkdva 322
                 69*************..7887788888888777778999989999999999999999999999999998888888888888888888877777777777 PP

                 ........HTEEEEEXGGXXGGSXHHHHHHHTTSSHHHHHHHHHHHHHHHHHHTHHHHHHHXTTTS.......XXXHCCCCC.HCCCHEEEE....... CS
                 ........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxx.xxxxxxxxx....... RF
         SET  37 ........aylfslpeapknlaftkelakasastllqklakdqkqaekedtdaalkasskaesdln.......askpeagaf.saiagysid....... 112
                          y+  l                     ++++a +  q+++  ++ ++k +   + d+        +      ++ s++ ++ ++       
  EEA21306.1 323 dpkdkadyLYFLLL---------------------GRAIAMAATQDMHPLEMPEIKYIWGDFHDYHpdadnesK------EEySLPFSFQLNilqptrl 394
                 77777764333334.....................477777777777777777777777777777643322220......2223333333224444444 PP

                 .........TEEEEEECCC............................GTTGGGCEEXSSSSEEEEEEEETTSSEEEEEES CS
                 .........xxxxxxxxxx............................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         SET 113 .........aralksgnga............................gplarflNHsCdpNcnltvqnvlrgprvavfAt 155
                          ++   +++++                             pl+ + NHsCdpN+  +++    g+++++  +
  EEA21306.1 395 leemgldpfTTLARYDTWIlntlyakfrgtasgrlstwdggpevcavHPLWCLANHSCDPNV--RWEW---GGEICFMVR 469
                 444444455333333333355555555555556666777888********************..8888...778877665 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.063
                 BXTTEEEEEXT CS
                 xxxxxxxxxxx RF
         SET 158 IkkGeEltidY 168
                 I+kGeE+++ Y
  EEA21306.1 499 IRKGEEILNHY 509
                 9********99 PP

>> zf-MYND  MYND finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   5.2   7.7e-07    0.0034       1      38 []     258     309 ..     258     309 .. 0.79
   2 ?   -0.5   0.4       0.3   1.3e+03      12      17 ..     532     537 ..     518     540 .. 0.83

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 7.7e-07
                 -TTT--..............B-SC..E-TTTS-SEESSHHHHHHCH.HHHCCCH CS
     zf-MYND   1 CavCgk.............aealk..kCagCksvfYCskeCqradw.ksHkteC 38 
                 C  C+               e  +   Ca C  + +Cs++C  ++  ++H   C
  EEA21306.1 258 CDACNGplpdlsvptekerGE--RavACASCDDIIFCSQKCHDEAQeTYHGAIC 309
                 777777777777776654333..256********************999*9988 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.3
                 E-TTTS CS
     zf-MYND  12 kCagCk 17 
                 +Ca+C+
  EEA21306.1 532 QCARCQ 537
                 899996 PP

>> TPR_9  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.3   1.3e-05     0.057      25      57 ..      23      57 ..      12      73 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 1.3e-05
       TPR_9 25 aPddpeerrdRGlllaqlGclsaAladLeayl..a 57
                +P+ p+ ++dR+ l+a+lG +  A+ad  ++l   
  EEA21306.1 23 DPHNPQIYLDRAKLYAKLGFYDLAAADAYRALtlL 57
                8*************************988888552 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.6   5.4e-05      0.24      23      42 .]      22      41 ..      21      41 .. 0.95

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 5.4e-05
      TPR_11 23 ldPdnaeayynLGlayykqG 42
                +dP n+ +y+ ++++y+k+G
  EEA21306.1 22 YDPHNPQIYLDRAKLYAKLG 41
                8*****************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (543 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       455  (0.0253779); expected 358.6 (0.02)
Passed bias filter:                      344  (0.0191868); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3831.86
//
Query:       EEA21307.1  [L=1090]
Description: WD repeat-containing protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.9e-19   68.3  12.0    3.6e-05   24.4   0.1    6.2  6  WD40         WD domain, G-beta repeat
    2.7e-05   24.4   0.0      0.031   14.6   0.0    3.9  4  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
  ------ inclusion threshold ------
      0.029   12.6   0.5        2.7    6.0   0.1    2.3  2  CRT10        CRT10


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4   0.1   6.1e-09   3.6e-05       4      37 ..      39      73 ..      36      74 .. 0.89
   2 !   12.4   0.0   3.9e-05      0.23       6      38 .]      90     125 ..      86     125 .. 0.81
   3 !   14.5   0.1   8.3e-06     0.049       3      38 .]     166     202 ..     157     202 .. 0.81
   4 ?   -1.6   0.0         1   6.2e+03       9      18 ..     327     339 ..     316     354 .. 0.57
   5 !   13.3   0.3     2e-05      0.12       5      38 .]     897     934 ..     893     934 .. 0.72
   6 !    6.7   0.0    0.0025        15       7      37 ..     944     975 ..     939     976 .. 0.77

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 6.1e-09
                EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40  4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37
                + +l GH ++v++l++s +g++lasGsdD  + i+
  EEA21307.1 39 VNELGGHtGCVNALSWSNSGRLLASGSDDTYLNIY 73
                56799**777*******************999987 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 3.9e-05
                 EEESS.SSEEEEE...EETTSSEEEEEETTSEEEEEE CS
        WD40   6 tltGH.ssvtsla...fspdgawlasGsdDgtvriWd 38 
                 + tGH  ++ s++    s d+++l++++ D  vri+d
  EEA21307.1  90 INTGHtANIFSVKfmpHSNDQTLLTCAG-DSEVRIFD 125
                 458**777*****997888888887778.******98 PP

  == domain 3  score: 14.5 bits;  conditional E-value: 8.3e-06
                 EEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 
                 + r+++ Hs+ v  + + ++  +++++s+Dg vr Wd
  EEA21307.1 166 NSRVYRSHSDrVKRIVTESSPYLFLTCSEDGEVRQWD 202
                 6789999955699996666666668***********9 PP

  == domain 4  score: -1.6 bits;  conditional E-value: 1
                 SSSSEEEEE.....E CS
        WD40   9 GHssvtsla.....f 18 
                 GH  +t+++      
  EEA21307.1 327 GH--ITACKisdarP 339
                 55..99997444440 PP

  == domain 5  score: 13.3 bits;  conditional E-value: 2e-05
                 EEEESSSS...EEEEE.EETTSSEEEEEETTSEEEEEE CS
        WD40   5 rtltGHss...vtsla.fspdgawlasGsdDgtvriWd 38 
                  +++GH++   v ++  +  d  +++sG+d g+v +Wd
  EEA21307.1 897 MIYRGHCNiktVKDVNyYGLDDEYVVSGCDSGHVFMWD 934
                 689***552445555255557777*************9 PP

  == domain 6  score: 6.7 bits;  conditional E-value: 0.0025
                 EESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   7 ltGH.ssvtslafspdgawlasGsdDgtvriW 37 
                 l+G    v+ ++ +p+ + la ++ D+t++i+
  EEA21307.1 944 LEGDgETVNIVQGHPYEPTLAVSGLDNTIKIF 975
                 5555334888899*******97777******7 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   5.2e-06     0.031      36      69 ..      44      77 ..      35     105 .. 0.86
   2 ?    1.0   0.0     0.088   5.3e+02      43      68 ..     100     127 ..      86     139 .. 0.77
   3 ?    0.1   0.0      0.17   9.9e+02      47      77 ..     915     945 ..     897     955 .. 0.79
   4 ?    2.8   0.0     0.024   1.4e+02      35      68 ..     945     978 ..     927     988 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 5.2e-06
  ANAPC4_WD40 36 kedsevrsLaWkpdgklLavaysdgevrlldaes 69
                 ++ + v++L+W+++g+lLa + +d+ +++++ + 
   EEA21307.1 44 GHTGCVNALSWSNSGRLLASGSDDTYLNIYSYHP 77
                 56789************************99765 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.088
  ANAPC4_WD40  43 sLaW..kpdgklLavaysdgevrlldae 68 
                  s+++  + +++ L     d+evr++d+e
   EEA21307.1 100 SVKFmpHSNDQTLLTCAGDSEVRIFDVE 127
                  555522457889999999********98 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.17
  ANAPC4_WD40  47 kpdgklLavaysdgevrlldaesgkvvhsls 77 
                    d++  + +++ g+v + d +++++v+ l+
   EEA21307.1 915 GLDDEYVVSGCDSGHVFMWDRKTANIVNILE 945
                  45889999*****************998765 PP

  == domain 4  score: 2.8 bits;  conditional E-value: 0.024
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdgevrlldae 68 
                  ++++++v+ ++ +p +  Lav+  d++++++++ 
   EEA21307.1 945 EGDGETVNIVQGHPYEPTLAVSGLDNTIKIFSSD 978
                  567888999999999****************986 PP

>> CRT10  CRT10
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.1   0.00046       2.7     175     253 ..      56     136 ..      29     192 .. 0.77
   2 ?    4.4   0.0    0.0015       8.8     101     133 ..     903     937 ..     899     963 .. 0.75

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.00046
       CRT10 175 dsislialsdnsqgitllaydkd..kerfyiekeiqtsh..nvPcvsfvknednseghitvayasisgevvtlkfk..fkeedgp 253
                 +s  l+a ++  + + ++ y+ d   + f+   +i+t h  n+ +v f+++++++    ++++a    ev ++ ++  fk+ ++p
  EEA21307.1  56 NSGRLLASGSDDTYLNIYSYHPDssTSPFALTTSINTGHtaNIFSVKFMPHSNDQT---LLTCA-GDSEVRIFDVEysFKNASNP 136
                 8999*******************777778888888875555***********7766...55555.56799999999445555554 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.0015
       CRT10 101 htinflkivnflG..qevLvaciddGivllwevst 133
                 ++i  +k vn++G  +e++v ++d+G v +w  +t
  EEA21307.1 903 CNIKTVKDVNYYGldDEYVVSGCDSGHVFMWDRKT 937
                 56666777777775579**************6433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1090 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       526  (0.0293379); expected 358.6 (0.02)
Passed bias filter:                      387  (0.0215851); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.85u 0.29s 00:00:01.13 Elapsed: 00:00:00.47
# Mc/sec: 6909.51
//
Query:       EEA21308.1  [L=540]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (540 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1144  (0.0638072); expected 358.6 (0.02)
Passed bias filter:                      517  (0.028836); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.58u 0.26s 00:00:00.84 Elapsed: 00:00:00.41
# Mc/sec: 3985.00
//
Query:       EEA21309.1  [L=267]
Description: 6-phosphogluconolactonase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.1e-71  239.1   0.0    5.7e-71  239.0   0.0    1.0  1  Glucosamine_iso  Glucosamine-6-phosphate isomerases/6-phospho


Domain annotation for each model (and alignments):
>> Glucosamine_iso  Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  239.0   0.0   3.2e-75   5.7e-71       4     223 ..      16     247 ..      13     249 .. 0.92

  Alignments for each domain:
  == domain 1  score: 239.0 bits;  conditional E-value: 3.2e-75
                      HHHHHHHHHHHHHHHHHHHHHHS-EEEEE--SHCHHHHHHHHHCSG.GGG..GS-GGGEEEEESEEESS-TTSTT-HHHHHHHHTGGGS-..-- CS
  Glucosamine_iso   4 eelaealaarivealeealaergraslalsGGstpkalyealaeeeeaaa..aldwskvhvflgDERfVpaddpdsNaklareallskvk..ip 93 
                      ++la++l +++++++++al+++g++++a+sGGs+p++l +al +  + +a  + ++sk+++f++DER Vp d+pdsN++l++e+ll+k++  + 
       EEA21309.1  16 DSLATHLRKYVLNNQHAALNKHGVFRVAVSGGSLPNTLAKALLAPGNGSAedTAQFSKWEIFFADERAVPLDHPDSNYRLIKEELLDKIPtqLG 109
                      789***************************************988766668888*********************************9752233 PP

                      GGGEE-S-TTSST..HHHHHHHHHHHHHHHHCC....SSSSSESEEEE---TTS-BTTB-TTCHHHHCSSSSEEEESSBSTSSS-EEEE-HHHH CS
  Glucosamine_iso  94 eanvhpikesaae..apeaaaaayeeelkella....kelpvfDlvlLGmGpDGHtaSLFPgspeleetdrlvvavedspkpppeRitlTlpvl 181
                      + +v+pi+e++ +  +p + a+ y e lk+ +a     ++pvfDl+lLG+GpDGHt+SLFPg+p+l+e+d++vv+v+dspkppp+RitlTlpv+
       EEA21309.1 110 APKVFPIDEKHVHdeDPTELADLYTEVLKHSFAakdsVKFPVFDLILLGVGPDGHTCSLFPGHPQLREEDAWVVGVSDSPKPPPKRITLTLPVV 203
                      55*****9665555689**************99****9******************************************************** PP

                      TTCSEEEEEEESHHHHHHHHHHHTT..TTTSGGGGH-..-SSEE CS
  Glucosamine_iso 182 nsarevlflvaGeeKaealeevlsgedpeelPaalve..gqgel 223
                      ++a +++f+++G +K+++++++++++++++lP+ lv+    +++
       EEA21309.1 204 KHALSIAFVATGGGKKDIMKRIFDTDESQSLPSGLVNilAGDKV 247
                      ************************99999*****9974333555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (267 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       377  (0.0210274); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.25s 00:00:00.67 Elapsed: 00:00:00.39
# Mc/sec: 2052.22
//
Query:       EEA21310.1  [L=259]
Description: short chain type dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.4e-47  160.6   0.4    5.4e-47  160.3   0.4    1.0  1  adh_short_C2   Enoyl-(Acyl carrier protein) reductase
    1.8e-37  128.7   1.4    2.4e-37  128.3   1.4    1.1  1  adh_short      short chain dehydrogenase
    0.00079   19.4   0.0     0.0011   18.9   0.0    1.2  1  KR             KR domain
  ------ inclusion threshold ------
      0.014   15.4   0.4      0.023   14.7   0.4    1.4  1  AdoHcyase_NAD  S-adenosyl-L-homocysteine hydrolase, NAD bindi
       0.02   14.8   0.5      0.029   14.2   0.5    1.3  1  3HCDH_N        3-hydroxyacyl-CoA dehydrogenase, NAD binding d
      0.043   13.1   0.3      0.083   12.2   0.3    1.4  1  THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase,


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  160.3   0.4   1.8e-50   5.4e-47       4     234 .]      20     257 ..      16     257 .. 0.90

  Alignments for each domain:
  == domain 1  score: 160.3 bits;  conditional E-value: 1.8e-50
                   TSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSE.E.....EE--TTSHHHHHHHHHHHHHHH..SSEEEEEE-----EGCSS-GGGH-H CS
  adh_short_C2   4 sgIGraiAkalaeeGaevvltdlneeakkrveelaeelgae.v.....lecDVtdeeqvealveevvekf..gklDilvnnagiapklkgpfletsr 92 
                    gIG++iA ala++Ga vv+  ++++++ r++++ae l+++ v     +++DV+++e  + lvee  + f  ++++ilvnna+      +pfl++s 
    EEA21310.1  20 TGIGAGIATALARNGAWVVINHVSDKSAPRAAKVAETLNQNtVgkavvVQADVSSPEGAKMLVEEGLRLFgvDHVHILVNNAASGSV--EPFLKASP 114
                   7**************************999999999998554344457**********************8889************9..******** PP

                   HHHHHHHHHHTHHHHHHHHHHHHHCTSCCEEEEEEEGGGTSBSTTTT.HHHHHHHHHHHHHHHHHHHHGG.GTEEEEEEEE--BHCTGGGGSTTHHH CS
  adh_short_C2  93 eefdraldvnlyslfllakaalplmkeggsivnlssvgaervvpnyn.aygaaKaalealtrylAvelgp.kgiRvNavspgpikTlaasgikgfde 187
                   + ++ ++++ + + +++++a++p+m +gg+i+n+ sv++ +v p+   +y+ aKaa+ a+t  + +elg+ +g+++Nav pg ++T+a  +   +++
    EEA21310.1 115 SFMEGMFKTIVFGPVYMIQAVIPHMPRGGRIINTGSVAS-KVCPGPVpIYSGAKAAVDAMTFGMSMELGRgYGVTINAVMPGGVATDALPKEV-MEK 209
                   *************************************77.56666555*********************99*****************65544.567 PP

                   HHHHHHHHST.TSS-B-HHHHHHHHHHHCSGGGTT--SEEEEESTTGG CS
  adh_short_C2 188 lleelearap.lgrlgtpeevaeaalfLasdeasyitGqtlvvDgGlt 234
                   l + l a++   +r+gt+e++++a+l L+s+ +++itGq++ v gG+t
    EEA21310.1 210 LHQPLIAMTRaEERIGTIEDIGDAVLLLCSENSRWITGQVISVSGGIT 257
                   7666666655156799******************************87 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  128.3   1.4   8.1e-41   2.4e-37       1     189 [.       9     204 ..       9     209 .. 0.93

  Alignments for each domain:
  == domain 1  score: 128.3 bits;  conditional E-value: 8.1e-41
                 SEEEEESTTS..HHHHHHHHHHHHTT-EEEE...EESCHHHHHHHHHHHHHT.TSEEEEEE-TTTSHHHHHHHHHHHHHHH..SSESEEEE---SS--S CS
   adh_short   1 kvvlvtGass..GIGraiakelakeGakvvv...vdrseekleevakelkee.gakalaiqvDvtdreevealvekavkkl..gkldvLvnNAGitgsg 91 
                 kv+++tG ++  GIG  ia +la++Ga vv+    d+s+ ++++va+ l+++   ka+++q+Dv++ e ++ lve+    +  +++++LvnNA+   ++
  EEA21310.1   9 KVAIITGSGRetGIGAGIATALARNGAWVVInhvSDKSAPRAAKVAETLNQNtVGKAVVVQADVSSPEGAKMLVEEGLRLFgvDHVHILVNNAASGSVE 107
                 89****987444*****************98654678888999*******99999************************99778*************** PP

                 SGGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGG.GTEEEEEEEESSBSSHHHHH CS
   adh_short  92 pfselseeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelap.tgirvnavaPGlvdTdmake 189
                 pf + s + +e ++++ ++g++ +++av+p+m   ++GrI+n++Sva+kv    v+ Ys +Kaav+++t  +++el + +g+++nav+PG+v+Td   +
  EEA21310.1 108 PFLKASPSFMEGMFKTIVFGPVYMIQAVIPHMP--RGGRIINTGSVASKVCPGPVPIYSGAKAAVDAMTFGMSMELGRgYGVTINAVMPGGVATDALPK 204
                 *******************************99..9****************************************86478*************98755 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.0   3.8e-07    0.0011       5     158 ..      13     172 ..      10     190 .. 0.78

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 3.8e-07
                 EETTT..SHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-.EEEE----TT-HHHHHHHHHHHHHHS..S---EEEE---------TT CS
          KR   5 itGGl..GgLGlelarwlaekgarhlvllsRsaaadedskaliaelealga.evevvaaDvsdkdavealleeikaee..ppikGvihaAgvlrdklle 98 
                 itG     g+G  +a+ la++ga  ++    + ++ +++++  ++l+++ + +  vv+aDvs+++  + l+ee  + +  + ++  ++ A     +++ 
  EEA21310.1  13 ITGSGreTGIGAGIATALARNGAWVVINHVSD-KSAPRAAKVAETLNQNTVgKAVVVQADVSSPEGAKMLVEEGLRLFgvDHVHILVNNAASGSVEPFL 110
                 666532269*************9888876666.56777777899999997778999*****************99999899999999999999999999 PP

                 T--HHHHHHHHTTTTHHHHHHHHHTTT..S--SEEEEEEEHHHHH--TT-HHHHHHHHHHHH CS
          KR  99 emtaedleqvlapKvkGawnLhelled..esldffvlfSSiagllgsagqanYaaaNaflDa 158
                 + + + +e +++  v G   + +++ +   +   ++ + S+a+ +       Y+ a a +Da
  EEA21310.1 111 KASPSFMEGMFKTIVFGPVYMIQAVIPhmPRGGRIINTGSVASKVCPGPVPIYSGAKAAVDA 172
                 99999999999988888777766655533444556666666666665555666666666666 PP

>> AdoHcyase_NAD  S-adenosyl-L-homocysteine hydrolase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   0.4   7.8e-06     0.023      21      63 ..       6      51 ..       1      86 [. 0.80

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 7.8e-06
                   -TTSEEEEE--SH...HHHHHHHHHHHCT-EEEEE-S-HHHHHHHH CS
  AdoHcyase_NAD 21 laGkvavvaGyGd...vGkGcaaslkglGarvivtevdPicalqaa 63
                   laGkva+++G G    +G G a++l   Ga v++  v   +a +aa
     EEA21310.1  6 LAGKVAIITGSGRetgIGAGIATALARNGAWVVINHVSDKSAPRAA 51
                   89*********9544499*****************99887777665 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.5   9.8e-06     0.029       6      60 ..      15      72 ..       9      87 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 9.8e-06
                --SC...CHHHHHHHHHHTT-EEEEE-S-HHHHHHHHHHHHHHHHCCTTTTSS-HHHH CS
     3HCDH_N  6 GaGt...mGagiaavfasagleVvlvdiseealekalekieksleklvekgklkeeev 60
                G+G    +Gagia+++a++g  Vv+  +s++++ +a++ +e+  ++ v k  + +++v
  EEA21310.1 15 GSGRetgIGAGIATALARNGAWVVINHVSDKSAPRAAKVAETLNQNTVGKAVVVQADV 72
                66644459****************************9999987777777777666665 PP

>> THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.3   2.8e-05     0.083      33      99 ..       5      74 ..       2      89 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2.8e-05
                   --TT-EEEEE-..--TTTHHHHHHHHHCTT-EEEEE-TTSCCHHHHHCCSSEEEE.-SS-TT-B-GGGS- CS
  THF_DHG_CYH_C 33 elegkkvvvvG..rsnivgkplallLleknatVtvchsktkdlaeitreadivvv.avGkpelikaemvk 99
                   +l+gk +++ G  r + +g  +a+ L++++a V + h + k+ ++  + a+ +    vGk+ +++a++ +
     EEA21310.1  5 SLAGKVAIITGsgRETGIGAGIATALARNGAWVVINHVSDKSAPRAAKVAETLNQnTVGKAVVVQADVSS 74
                   678898888852267789*********************************9975279999999998755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (259 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       532  (0.0296726); expected 358.6 (0.02)
Passed bias filter:                      425  (0.0237046); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.44u 0.29s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 1803.15
//
Query:       EEA21311.1  [L=358]
Description: hypothetical protein PMAA_051220 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.2e-12   46.5   0.3    4.2e-12   45.6   0.2    1.6  1  Fungal_trans_2  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.6   0.2   2.3e-16   4.2e-12      31     178 ..       1     148 [.       1     296 [. 0.70

  Alignments for each domain:
  == domain 1  score: 45.6 bits;  conditional E-value: 2.3e-16
  Fungal_trans_2  31 lalsnkallhallalsafhlqskgpkds....lereakrykslalkelqealaelsstlsrnekykdiLaaiLllcsieissgdvsdwrvhLeaa 121
                     +al++   ++ ++a +a++++++ +++       +e + y+ ++l ++ + l+  + + s     + ++++iL l+ ++i++g   +w +h+++ 
      EEA21311.1   1 MALTDATAFQLCMANAAMFMAQRKQPETfqyeKCSETLEYYGKCLGQITKRLESRDDCAS-----DGVIVTILGLICHDIYVGLWARWATHIKGL 90 
                     78999999************777777777988568999**********************.....****************************** PP

  Fungal_trans_2 122 tsliksrggskasssslsskarfllrifayldilssttlgrgpsfpseeyekllen..........k 178
                     +++i+ rgg     +++ss    l  + ++ d l+s t +  +++++ ey   l+           +
      EEA21311.1  91 RRIIELRGGY----RNISS---NLALWASWYDALGSATHD--TCPQFPEYMCDLSPacqpvrtprlE 148
                     **********....55555...467799999*********..7777777776666644444433322 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (358 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       409  (0.0228122); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 2333.65
//
Query:       EEA21312.1  [L=222]
Description: ribonuclease H1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.7e-20   72.6   0.0    6.1e-20   71.9   0.0    1.3  1  RNase_H   RNase H


Domain annotation for each model (and alignments):
>> RNase_H  RNase H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.9   0.0   3.4e-24   6.1e-20       4     112 ..      58     184 ..      55     188 .. 0.84

  Alignments for each domain:
  == domain 1  score: 71.9 bits;  conditional E-value: 3.4e-24
                 EEEEEEEEEECT.TTCEEEEEEECTT..E..EEEEEEC.CCCHHHHHHHHHHHHHHH.TT.....SC...........SEEEEEES-HHHHHHHHCCCH CS
     RNase_H   4 vvvYtDGsclgn.pgeggagavlykegar..nisaple.eaqtnnraELsAvieaLk.al....ksd...........ekvniytDSkYvvkgitqwvh 82 
                 +++ +DG+c++n ++e++a++++y++++   n+s +l+ +  tn+ aEL+A + aL+ a+    + +           + v+i++DS+Y+vkg+tqw  
  EEA21312.1  58 IIIAVDGACRHNgTSEAQAAIGVYFGKQSlnNRSVRLNiDNPTNQIAELTAGFYALRrAMllakR-GllteddegkqlSMVVIKSDSEYLVKGMTQWTL 155
                 57889*******99999****998887445699999*999*****************65567650.2555556677778899***************** PP

                 HHHHTTSSSETTSSBHTTHHHHHHHHHCHC CS
     RNase_H  83 rwkknawkttseqkpvknkdlaellkelak 112
                 +wkkn+ ++++   pv+n++l+++l+++ +
  EEA21312.1 156 KWKKNGFRNAKGA-PVVNAELFQKLEQAYQ 184
                 *******777666.*********9987655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (222 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       340  (0.0189637); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.23s 00:00:00.69 Elapsed: 00:00:00.42
# Mc/sec: 1576.57
//
Query:       EEA21313.1  [L=131]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
  ------ inclusion threshold ------
       0.02   14.7   0.1       0.04   13.8   0.1    1.5  1  Reo_sigmaC_M  Reovirus sigma C capsid protein triple beta spi


Domain annotation for each model (and alignments):
>> Reo_sigmaC_M  Reovirus sigma C capsid protein triple beta spiral
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.1   2.2e-06      0.04      15      33 ..      53      71 ..      41      74 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2.2e-06
  Reo_sigmaC_M 15 adGvVSLdmDPYFCSqrvs 33
                  a+GvV   m  Y+CS + s
    EEA21313.1 53 AQGVVQFGMNSYYCSRSLS 71
                  8**************9877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (131 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       507  (0.0282782); expected 358.6 (0.02)
Passed bias filter:                      406  (0.0226449); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.28s 00:00:00.67 Elapsed: 00:00:00.42
# Mc/sec: 942.82
//
Query:       EEA21314.1  [L=202]
Description: HHE domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.6e-14   54.6   0.5    2.6e-14   53.9   0.5    1.3  1  Hemerythrin  Hemerythrin HHE cation binding domain


Domain annotation for each model (and alignments):
>> Hemerythrin  Hemerythrin HHE cation binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.9   0.5   1.5e-18   2.6e-14       2     126 ..      16     128 ..      15     131 .. 0.95

  Alignments for each domain:
  == domain 1  score: 53.9 bits;  conditional E-value: 1.5e-18
                  HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHH..CCC.HHHHHHHHHHHHHHHHHHHHHHHHCHTCG CS
  Hemerythrin   2 ivealdeeHralrallerlraladaaaevhgalrklaelldelvdeleaHhaaEEellfPlle.drpggravldvlereHdeirelleelrellkgle 98 
                  i ++++++H alr+  + +   +d        l++ +++ +++ ++l++H   EE +++P+le  +++g+   d+ +++H+ + + l ++++l  + +
   EEA21314.1  16 ISDTIKHDHVALRNGYNKILGTTD--------LDERRRWQNQFTWDLARHAVGEELVVYPALEkVVADGKRIADRDREDHQIVKKYLYKFQALNPTDT 105
                  5689*************9977777........799*************************************************************99 PP

                  GSTCHHHHHHHHHHHHHHHHHHHHHHHT CS
  Hemerythrin  99 epsaaafaelleeladllreHiakEesi 126
                       +f+  l++l  +l  Hi+kEe++
   EEA21314.1 106 -----EFEPTLRNLWGDLSAHIRKEEEE 128
                  .....9********************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (202 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       452  (0.0252106); expected 358.6 (0.02)
Passed bias filter:                      386  (0.0215294); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.46
# Mc/sec: 1319.95
//
Query:       EEA21315.1  [L=431]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
     0.0035   16.6   0.0       0.11   11.6   0.0    2.1  2  Aminotran_1_2  Aminotransferase class I and II


Domain annotation for each model (and alignments):
>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.6   0.0   6.4e-06      0.11      32     145 ..      41     154 ..      12     160 .. 0.74
   2 !    2.9   0.0    0.0028        51     216     246 ..     248     277 ..     238     323 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 6.4e-06
                    HHHTSTTST-BTTHHHHHHHHHHHHHCTCTTCHTTGGEGEEEESHHHHHHHHHHHHHHHTT..T-EEEEEESS-THHHHHHHHTTSEEEEEEBEET CS
  Aminotran_1_2  32 laggtlneygpidglpeleealakflgrseklklkreaavvvgsGagaliealifllklnp..gdeilvpdptyasyknilrlsggevvryplyse 125
                    +   ++  ygp+ g p+l++++a++l+r  +    ++a+++ +   ++l+  +      +p   ++i++ +pty    +i++ +g++ +     +e
     EEA21315.1  41 ARATDVMLYGPNIGDPALRKDIAEWLSR-LYCLRSPQAQIQKLRSRSQLPRSALLSGFTDPvyARRIWMVEPTYFLACTIFEDAGFQGRLTG-VPE 134
                    45567889*******************5.555555666999999999997655544424553368899999999999999999999955444.347 PP

                    TTTEE-HHHHHHHHTTHHCT CS
  Aminotran_1_2 126 edfhldlealeealkeapeg 145
                     d ++d+e l + +++  e+
     EEA21315.1 135 GDDGVDVEFLRARINDVDEE 154
                    77788888888888876655 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.0028
                    EEESSSTTSSGGG-EEEEEEEHHHHHHHHHH CS
  Aminotran_1_2 216 vgslsKafGlaGeRvGyilgnaavvsqlrkl 246
                     gs+sK +G +G R+G++ ++++++  l+ +
     EEA21315.1 248 NGSFSKVLG-PGMRCGWAEATPDFITRLNLV 277
                    69*******.9*********99666655543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (431 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       262  (0.0146132); expected 358.6 (0.02)
Passed bias filter:                      254  (0.014167); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.49
# Mc/sec: 2667.30
//
Query:       EEA21316.1  [L=487]
Description: RNA binding protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-11   42.5   0.0    2.9e-05   23.8   0.0    3.3  2  RRM_1     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.2   0.0   3.3e-06      0.06       1      52 [.      25      77 ..      25      82 .. 0.85
   2 !   23.8   0.0   1.6e-09   2.9e-05       1      69 [.     324     403 ..     324     404 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 3.3e-06
                EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHH CS
       RRM_1  1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedA 52
                l++ ++p+ + ++eLk++ ++     +  +v+d ++g ++g + +  +++++A
  EEA21316.1 25 LYLQGIPQHCRWQELKDFVRQTALHIRQAVVYDdQHGYPTGLGQIIVKNEDEA 77
                7999*****************6655555555555***********99999998 PP

  == domain 2  score: 23.8 bits;  conditional E-value: 1.6e-09
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTT..........SEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etg..........kskgfafVeFeskedAekAlealngkklggrel 69 
                 +++ n+ p v+ ++L ++F++ G + +++++rd e+g          + +++a  +F + e+Ae+A+  +ng  lgg+++
  EEA21316.1 324 IIIDNICPGVDIQTLQDHFRDAGHMLHCQIIRDnENGhearcnelsyPGQCYATATFSTAEEAERAVGMYNGSDLGGSRV 403
                 6799999**************************9555222222222234689************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (487 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       443  (0.0247086); expected 358.6 (0.02)
Passed bias filter:                      329  (0.0183502); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.26s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 3264.48
//
Query:       EEA21317.1  [L=801]
Description: cell cycle control protein (Cwf22), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-29  101.4   0.0    7.5e-29  100.0   0.0    1.8  2  MA3       MA3 domain
    5.1e-12   45.9   0.1    9.3e-12   45.0   0.1    1.4  1  MIF4G     MIF4G domain


Domain annotation for each model (and alignments):
>> MA3  MA3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.0       1.3   1.2e+04      49      64 ..     133     148 ..     128     152 .. 0.76
   2 !  100.0   0.0   8.4e-33   7.5e-29       1     112 [.     428     533 ..     428     534 .. 0.99

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 1.3
                 .SS--HHHHHHHHHHH CS
         MA3  49 sktyneyygllleklc 64 
                 sk+y++++++ l+k +
  EEA21317.1 133 SKEYQRMAWEALKKSI 148
                 7889999999888876 PP

  == domain 2  score: 100.0 bits;  conditional E-value: 8.4e-33
                 HHHHHHHHHHSSS...SHHHHHHHHHHTT--.TTHHHHHHHHHHHHHHS.SS--HHHHHHHHHHHCC-HHHHHHHHHHHHHHHHGGGGS-HH...HHHH CS
         MA3   1 lrrkifliieeylssgdyeeavsklekLklp.kqeheivkillecaleesktyneyygllleklceknlilkkqfekgfwdvlesledleldipeairn 98 
                 lrr i+l+i++++   d+ee+++kl+k++lp   e+e++++++ec+ +e +ty+++ygl+ e++ + n+++++ fe++f +++e+++++e++   ++rn
  EEA21317.1 428 LRRTIYLTIMSSV---DFEECCHKLMKISLPpGKEPELPSMIIECCSQE-RTYSKFYGLIGERFAKLNRLWSDLFEESFAKYYETIHRYETN---RLRN 519
                 69***********...*********************************.******************************************...**** PP

                 HHHHHHHHHHTTSS CS
         MA3  99 laefvarlisediL 112
                 +a+f+++++s+d++
  EEA21317.1 520 IARFFGHILSNDAI 533
                 ***********987 PP

>> MIF4G  MIF4G domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.0   0.1     1e-15   9.3e-12       2     211 ..     146     327 ..     145     328 .. 0.96

  Alignments for each domain:
  == domain 1  score: 45.0 bits;  conditional E-value: 1e-15
                 HHHHHHHHCHTTTTHHHHHHHHHHHHHCSCHHHHHHHHHHHHHHHHHCGGGHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHC-S-HHHHHHHHHH CS
       MIF4G   2 kkvkgilnklskenfevlikqllklamdddknelkevielifekaveepsfsplyarlcgklnsrfqqnFrikllnklqeefekryeleneleenedgn 100
                 k ++g++nk+  +n+++++ +l   +       +  + ++i++ +  +  f p ya +++ +n++++  +++ ll +l+ +f+k           ++ +
  EEA21317.1 146 KSINGLINKVNVSNIKHIVPELFGENLIR---GRGLFCRSIMKAQAASLPFTPIYAAMAAIVNTKLP-QVGELLLGRLVVQFRK---------AFKRND 231
                 5689**********************996...9**********************************.****************.........777788 PP

                 HHHHHHHHHHHHHHHHTTSSEHHHHHHHHHHHHHGGCCCCSCCHSCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHCSSSSHHHH CS
       MIF4G 101 rrrrlglvrflgelfklkmltskilldclkellssltketaddppqdleeieilltllttigktlennekakkeldqffkriqkiledatrqelssrir 199
                 +  +++  +f+  l++++++++ +   +l  ll + t+          +++ei++ l + +g+ le  e + +     f+++++il +   + +++r++
  EEA21317.1 232 KAVCISSTTFIAHLCNQQVVHEMVAAQILLLLLHKPTD----------DSVEIAVGLTREVGQHLE--EMSGPIALAVFDQFRNILHE---ADIDKRVQ 315
                 88899*****************9999*********999..........******************..*******************9...9******* PP

                 HHHHHHHHHHHT CS
       MIF4G 200 fmlkdlielkkn 211
                 +m++ l++++k+
  EEA21317.1 316 YMIEVLFQVRKD 327
                 *********996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (801 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1015  (0.0566122); expected 358.6 (0.02)
Passed bias filter:                      665  (0.0370907); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.75u 0.31s 00:00:01.06 Elapsed: 00:00:00.47
# Mc/sec: 5103.76
//
Query:       EEA21318.1  [L=90]
Description: dolichol phosphate-mannose biosynthesis regulatory protein Dpm2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-30  104.9   0.8    2.3e-30  104.7   0.8    1.0  1  DPM2      Dolichol phosphate-mannose biosynthesis regulatory 
    0.00094   19.1   0.7     0.0011   18.9   0.7    1.1  1  PIG-P     PIG-P
     0.0078   16.3   0.2     0.0078   16.3   0.2    1.8  2  DUF4229   Protein of unknown function (DUF4229)
     0.0078   16.0   1.6      0.026   14.4   0.1    2.0  2  COX14     Cytochrome oxidase c assembly
  ------ inclusion threshold ------
       0.22   11.5   1.9       0.26   11.3   0.0    1.8  2  PilX_N    PilX N-terminal
       0.27   11.1   0.1       0.27   11.1   0.1    1.7  2  LapA_dom  Lipopolysaccharide assembly protein A domain


Domain annotation for each model (and alignments):
>> DPM2  Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.7   0.8   7.7e-34   2.3e-30       4      76 .]       5      77 ..       2      77 .. 0.98

  Alignments for each domain:
  == domain 1  score: 104.7 bits;  conditional E-value: 7.7e-34
        DPM2  4 lvGlllllvalllfvYYtiwvillPfvdedhvlhkyflpreyairipvillvvlllfvgtFiglvlikskkkk 76
                lvG+++llva+++f+YYt+w++l+Pfvd+ h+lh++f+pr +airipvil++++ ++vg+F+g+++i+s++kk
  EEA21318.1  5 LVGSAMLLVATAIFLYYTAWTLLMPFVDQGHPLHDLFPPRVWAIRIPVILTLLGSTVVGSFLGIMMIRSSRKK 77
                79********************************************************************997 PP

>> PIG-P  PIG-P
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.7   3.7e-07    0.0011       8      59 ..       9      61 ..       5      80 .. 0.73

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 3.7e-07
       PIG-P  8 vlyllstlafllyllwallPeevlha..lgityypnryWalavpayllmlvlyi 59
                ++ l++t +fl y +w+ll   ++++     +++p r Wa+ +p++l  l  ++
  EEA21318.1  9 AMLLVATAIFLYYTAWTLLMP-FVDQghPLHDLFPPRVWAIRIPVILTLLGSTV 61
                6789999**********9963.33332222578************998665444 PP

>> DUF4229  Protein of unknown function (DUF4229)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.3      0.34     1e+03      10      24 ..      11      25 ..       5      34 .. 0.52
   2 !   16.3   0.2   2.6e-06    0.0078      24      66 ..      45      87 ..      40      89 .. 0.89

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.34
     DUF4229 10 Lfvvltavillvarl 24
                L v++++ ++  a++
  EEA21318.1 11 LLVATAIFLYYTAWT 25
                333333334444433 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 2.6e-06
     DUF4229 24 liglpvpllvaallAlvvalplSmvllkklRdrataqvaerde 66
                ++++++p+++ +l + vv   l++++ ++ R++a+ + a++++
  EEA21318.1 45 VWAIRIPVILTLLGSTVVGSFLGIMMIRSSRKKAAKAKAAASK 87
                566779*****************************99888876 PP

>> COX14  Cytochrome oxidase c assembly
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.2      0.15   4.5e+02      21      38 ..      11      28 ..       8      33 .. 0.83
   2 !   14.4   0.1   8.7e-06     0.026      18      54 ..      53      89 ..      52      90 .] 0.89

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.15
       COX14 21 LiGvTlyaggllvytvys 38
                L+ +T++  + +++t  +
  EEA21318.1 11 LLVATAIFLYYTAWTLLM 28
                677899999999998655 PP

  == domain 2  score: 14.4 bits;  conditional E-value: 8.7e-06
       COX14 18 VltLiGvTlyaggllvytvysygkynrkqkaeliere 54
                +ltL+G T++++ l +++++s  k+  k+ka++++++
  EEA21318.1 53 ILTLLGSTVVGSFLGIMMIRSSRKKAAKAKAAASKKK 89
                89*****************************555544 PP

>> PilX_N  PilX N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.6      0.48   1.4e+03       2      10 ..       7      19 ..       5      31 .. 0.56
   2 ?   11.3   0.0   8.6e-05      0.26      13      46 ..      52      85 ..      45      85 .. 0.89

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.48
      PilX_N  2 Gia.Lvvtl...l 10
                G+a L v++   l
  EEA21318.1  7 GSAmLLVATaifL 19
                5555555333444 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 8.6e-05
      PilX_N 13 avltllgvatiqgslleerlsandrdriqafqaA 46
                ++ltllg++++ + l ++ ++++++    a++aA
  EEA21318.1 52 VILTLLGSTVVGSFLGIMMIRSSRKKAAKAKAAA 85
                56***********************999999998 PP

>> LapA_dom  Lipopolysaccharide assembly protein A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.5       1.3   3.8e+03      25      29 ..      13      17 ..       5      30 .. 0.49
   2 ?   11.1   0.1   8.9e-05      0.27      12      50 ..      45      82 ..      39      90 .] 0.61

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 1.3
    LapA_dom 25 vafgi 29
                va +i
  EEA21318.1 13 VATAI 17
                22222 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 8.9e-05
    LapA_dom 12 faqvelpLsllllvafgiGallgwllslwsylrlrrelr 50
                ++ + +p++l ll++ ++G +lg+ +  +   ++  +++
  EEA21318.1 45 VWAIRIPVILTLLGSTVVGSFLGIMMIRS-SRKKAAKAK 82
                57778899999999999998888777664.222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (90 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       707  (0.0394333); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.39u 0.24s 00:00:00.63 Elapsed: 00:00:00.41
# Mc/sec: 651.66
//
Query:       EEA21319.1  [L=81]
Description: dolichol phosphate-mannose biosynthesis regulatory protein Dpm2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.2e-28   97.2   0.8      6e-28   97.0   0.8    1.0  1  DPM2      Dolichol phosphate-mannose biosynthesis regulatory 
     0.0023   17.8   0.8     0.0025   17.7   0.8    1.1  1  PIG-P     PIG-P
     0.0043   17.1   1.6     0.0055   16.8   0.1    1.7  2  DUF4229   Protein of unknown function (DUF4229)
     0.0051   16.6   1.3       0.02   14.7   0.1    1.9  2  COX14     Cytochrome oxidase c assembly
  ------ inclusion threshold ------
       0.11   12.4   0.1        0.2   11.5   0.1    1.5  1  LapA_dom  Lipopolysaccharide assembly protein A domain


Domain annotation for each model (and alignments):
>> DPM2  Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.0   0.8   1.7e-31     6e-28       9      76 .]       1      68 [.       1      68 [. 0.98

  Alignments for each domain:
  == domain 1  score: 97.0 bits;  conditional E-value: 1.7e-31
        DPM2  9 lllvalllfvYYtiwvillPfvdedhvlhkyflpreyairipvillvvlllfvgtFiglvlikskkkk 76
                +llva+++f+YYt+w++l+Pfvd+ h+lh++f+pr +airipvil++++ ++vg+F+g+++i+s++kk
  EEA21319.1  1 MLLVATAIFLYYTAWTLLMPFVDQGHPLHDLFPPRVWAIRIPVILTLLGSTVVGSFLGIMMIRSSRKK 68
                799**************************************************************997 PP

>> PIG-P  PIG-P
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.8     7e-07    0.0025      11      59 ..       3      52 ..       1      72 [. 0.72

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 7e-07
       PIG-P 11 llstlafllyllwallPeevlha..lgityypnryWalavpayllmlvlyi 59
                l++t +fl y +w+ll   ++++     +++p r Wa+ +p++l  l  ++
  EEA21319.1  3 LVATAIFLYYTAWTLLMP-FVDQghPLHDLFPPRVWAIRIPVILTLLGSTV 52
                788999********9963.33332222578************998665444 PP

>> DUF4229  Protein of unknown function (DUF4229)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.1      0.32   1.1e+03      11      26 ..       3      18 ..       1      28 [. 0.55
   2 !   16.8   0.1   1.5e-06    0.0055      24      66 ..      36      78 ..      30      80 .. 0.89

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.32
     DUF4229 11 fvvltavillvarlig 26
                 v++++ ++  a+++ 
  EEA21319.1  3 LVATAIFLYYTAWTLL 18
                4444444444444444 PP

  == domain 2  score: 16.8 bits;  conditional E-value: 1.5e-06
     DUF4229 24 liglpvpllvaallAlvvalplSmvllkklRdrataqvaerde 66
                ++++++p+++ +l + vv   l++++ ++ R++a+ + a++++
  EEA21319.1 36 VWAIRIPVILTLLGSTVVGSFLGIMMIRSSRKKAAKAKAAASK 78
                566779*****************************99888876 PP

>> COX14  Cytochrome oxidase c assembly
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.1      0.12   4.3e+02      21      38 ..       2      19 ..       2      24 .. 0.81
   2 !   14.7   0.1   5.6e-06      0.02      18      54 ..      44      80 ..      43      81 .] 0.89

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.12
       COX14 21 LiGvTlyaggllvytvys 38
                L+ +T++  + +++t  +
  EEA21319.1  2 LLVATAIFLYYTAWTLLM 19
                667899999999999755 PP

  == domain 2  score: 14.7 bits;  conditional E-value: 5.6e-06
       COX14 18 VltLiGvTlyaggllvytvysygkynrkqkaeliere 54
                +ltL+G T++++ l +++++s  k+  k+ka++++++
  EEA21319.1 44 ILTLLGSTVVGSFLGIMMIRSSRKKAAKAKAAASKKK 80
                89*****************************555544 PP

>> LapA_dom  Lipopolysaccharide assembly protein A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.1   5.6e-05       0.2      12      50 ..      36      73 ..      30      81 .] 0.61

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 5.6e-05
    LapA_dom 12 faqvelpLsllllvafgiGallgwllslwsylrlrrelr 50
                ++ + +p++l ll++ ++G +lg+ +  +   ++  +++
  EEA21319.1 36 VWAIRIPVILTLLGSTVVGSFLGIMMIRS-SRKKAAKAK 73
                57778899999999999998888777664.222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (81 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       783  (0.0436723); expected 358.6 (0.02)
Passed bias filter:                      441  (0.024597); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.38u 0.21s 00:00:00.59 Elapsed: 00:00:00.38
# Mc/sec: 636.20
//
Query:       EEA21320.1  [L=1097]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
      0.065   13.4   0.0       0.15   12.3   0.0    1.5  1  NFACT-R_2  NFACT protein RNA binding domain


Domain annotation for each model (and alignments):
>> NFACT-R_2  NFACT protein RNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   8.3e-06      0.15      34      86 ..     675     727 ..     666     736 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 8.3e-06
   NFACT-R_2  34 slrakshkGplvlidgelseedlelaarivarYskgkeeeevevkvkkkegee 86 
                  ++ak++++++ l d+ +s++  +   r+varYs+  + + v+v +++++ge+
  EEA21320.1 675 LMQAKNCRSAVFLSDELASNSAATAHVRLVARYSRLTTSNIVDVVWTHPTGER 727
                 47999**********9999*****************************99987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1097 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       345  (0.0192426); expected 358.6 (0.02)
Passed bias filter:                      240  (0.0133861); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.71u 0.31s 00:00:01.02 Elapsed: 00:00:00.48
# Mc/sec: 6806.06
//
Query:       EEA21321.1  [L=234]
Description: HD superfamily hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0015   18.7   2.6     0.0024   18.1   0.3    2.1  2  HD        HD domain
  ------ inclusion threshold ------
       0.13   12.1   0.0       0.28   11.0   0.0    1.5  1  RMI1_C    Recq-mediated genome instability protein 1, C-termi


Domain annotation for each model (and alignments):
>> HD  HD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.3   2.6e-07    0.0024       4     121 ..      32     153 ..      31     154 .. 0.66
   2 ?    0.3   0.1     0.087   7.8e+02      43      75 ..     189     219 ..     170     228 .. 0.68

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 2.6e-07
                 HHHHHHHHHHHHHHHHHH........HHHHHHHHHHHHHTTTTHHHHTS..HHHHHHCTCCHHHHHHHHHHHHHHHHHHHHH..HHHHHHHHHTTCCHH CS
          HD   4 HsleVaklarrlaedlge........eedrellllaaLlHDiGkgpfgdafekkeeefekflaHekvgaeilrevekrlgld..ledvaklirehhesw 92 
                 H  +V  la r++ ++            ++ ++ l aLlHDiG  +      k  +++++  +  k  +  l  ++ +++l+  ++++++ +++ +e  
  EEA21321.1  32 HVHRVVSLALRIYASEVAlhqdtastKYNKTIITLSALLHDIGDHKYLP---K--DTNNSTTDPKKLVYNALISHGADENLAsrVQTIVNNVSYTNETR 125
                 55566666666555544457788888889999***********777333...2..23444445566666666666666655455555555555555555 PP

                 HHHHHHH...HHHCCTSCHHHHHHHHHHHHHH CS
          HD  93 egkkrpr...glaerqlslearivklaDrlaa 121
                 +    p+   +l   + ++e+ iv++aDrl+a
  EEA21321.1 126 N----PEhvqSLISTPGYHELAIVQDADRLDA 153
                 4....32245********************98 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.087
                 TS..HHHHHHCTCCHHHHHHHHHHHHHHHHHHH CS
          HD  43 gdafekkeeefekflaHekvgaeilrevekrlg 75 
                 ++++ek e++ + +   ++ g ei+re+  rl+
  EEA21321.1 189 EHFGEKLEKLEGMM--KTETGKEIARERTRRLK 219
                 45555543333333..37778888888777774 PP

>> RMI1_C  Recq-mediated genome instability protein 1, C-terminal OB-fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   3.1e-05      0.28      82     131 ..     172     221 ..     161     229 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 3.1e-05
      RMI1_C  82 lalkkdqkkrqklkealkeaqekLidleclmeielnpaskkpvvleledv 131
                 ++ +k ++k  +l+e ++++ ekL +le++m+ e  ++  +    +l+ +
  EEA21321.1 172 KRKEKPDQKLWELEESIEHFGEKLEKLEGMMKTETGKEIARERTRRLKVF 221
                 34455568889*********************998777666655555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (234 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       761  (0.0424452); expected 358.6 (0.02)
Passed bias filter:                      535  (0.0298399); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 1539.77
//
Query:       EEA21322.1  [L=712]
Description: dynamin GTPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.1e-32  111.6   0.0      1e-31  110.2   0.0    1.8  1  Dynamin_N     Dynamin family
    2.4e-30  105.8   5.1    4.3e-30  104.9   3.8    2.0  2  Dynamin_M     Dynamin central region
    0.00011   22.2   0.0     0.0005   20.1   0.0    2.2  1  MMR_HSR1      50S ribosome-binding GTPase
     0.0028   17.8   0.8      0.018   15.2   0.2    2.7  2  GED           Dynamin GTPase effector domain
  ------ inclusion threshold ------
      0.061   13.7   0.9        0.8   10.1   0.0    3.0  3  PriX          Primase X


Domain annotation for each model (and alignments):
>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.2   0.0   2.9e-35     1e-31       1     167 [.      46     242 ..      46     243 .. 0.77

  Alignments for each domain:
  == domain 1  score: 110.2 bits;  conditional E-value: 2.9e-35
                 EEEEEBTTTTHHHHHHHHHTS--S---SSS---S-EEEEECCT---C..............CS...SSEEEE.......T-EB--CHHHHHHHHHHHHH CS
   Dynamin_N   1 iavvGsqSsGKSSvlnaLlgedilprgpnptTrrplelqlgeeeeas..............eravkeelkek.......ekkledfsevreeieketek 78 
                 +av+G+qS+GKSSvl+ ++g + +pr+++++Tr p+e+ l ++e+++              +++ +++l +        ++  + ++ev + +e +  +
  EEA21322.1  46 LAVCGDQSAGKSSVLEGITGIP-FPRQEGLCTRFPTEIILCHSETSQqttitasirphssrTKEIQNTLASYrkvlqdiNELPSVIQEVSKRMEIRGYT 143
                 69********************.7****************77777664455555555333222222222222222223344444444444444444444 PP

                 HHTSSSS--SS-EEEEEEETTS-SEEEEE---B-SSSGTTS.........HHHHHHH.STTEEEEEEEETTS-CCC-CHHHHHHHHSTTBTTEEEEEE- CS
   Dynamin_N  79 iagankgiskkvillkilsllvkgltlvDlPGldsvnkrdq.........elvkeyi.kkadiilavtsanhdlsnsealflarevdpkgkrtivvltk 167
                  +g++ ++  + + ++i+++   +l++vDlPGl++v++ +          ++v+ y+  +++iilav++a++d+++++  +lar+ dp+g+rt++++tk
  EEA21322.1 144 EDGNGLAFAPDALRIEITGPIGLHLSVVDLPGLIEVPDDNRddedvnavmDMVTAYLeSSRTIILAVVQASNDVATQKIIRLARHHDPEGQRTVGIITK 242
                 55555555555**************************99999********************************************************9 PP

>> Dynamin_M  Dynamin central region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0      0.65   2.3e+03     105     129 ..     184     208 ..     177     226 .. 0.70
   2 !  104.9   3.8   1.2e-33   4.3e-30       7     283 ..     261     570 ..     255     572 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.65
   Dynamin_M 105 sdeektklllqlitkfkedfkklie 129
                  d+e  +++++++t++ e+ +++i 
  EEA21322.1 184 RDDEDVNAVMDMVTAYLESSRTIIL 208
                 3338889999999999998888874 PP

  == domain 2  score: 104.9 bits;  conditional E-value: 1.2e-33
   Dynamin_M   7 nkvipLklGYvgVvnRsqkdInkkksieealkkEkaFFeshpay.rkl.adkaGtpyLakkLnqiLvehIrkslPelkkkineklqklekeleelgesk 103
                  ++i+LklG++ V+n    +I+++ +++ + ++E +FF++ ++  ++l  +++G + L + L+ +L +hI+k+lP+ +++i+++l+++e+el+ +g+ +
  EEA21322.1 261 QDTIKLKLGFFLVKNPAPTEIKEQITMTFRSQRELEFFSEPKWAsQHLdRNRVGANKLRQFLQVLLDSHIEKELPKVRDEIKKSLTTTEAELRFMGDAR 359
                 4689***********************************9999999***************************************************99 PP

   Dynamin_M 104 psdeektklllqlitkfkedfkklieGe.........sevstkelsggar.ireiFne.........tlekslekidpleelsd............... 168
                 +s ++ ++++++l  k+ e ++++++G+         s+++ ++l+   + i+  F++         +       i   ++l++               
  EEA21322.1 360 SSVAHVRSFMTNLSMKYYELLQAALNGSyqsidvdffSQIEGSRLRARIQqINTDFAKhmrdcgerrK-------IGTASKLEQssvsstaqlmvtevq 451
                 9999************************8666554433344444554444466667775554444441.......333333333444555566667777 PP

   Dynamin_M 169 ..eeirtairnsrGrelplfvpekaFealvkkqikkleepalkcvelVyeelekivek.lek.elkrFpnLreeikevvedllreqeeptkemienlie 263
                    ++r+++ ++rG+elp+  + + +  l+++q  ++ ++a  ++  ++e +++  ek +++   +    Lr+e+ ++++d l+++e+ + e +++l+e
  EEA21322.1 452 mtAWVREVYMRTRGKELPGNHNLALLAELFHEQSLRWASIAEAHIVAIREVISQWTEKvVKNvVREDEDGLRREVGSILQDSLDNCEKLALEELNKLLE 550
                 77*******************************************9999999999999444453344466***************************** PP

   Dynamin_M 264 melayintnhpdfigalkai 283
                  e++   t ++ + ++ ++ 
  EEA21322.1 551 DERQSPLTYNHYYTDNIQKS 570
                 **************999886 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   0.0   1.4e-07    0.0005       2      96 ..      46     224 ..      45     243 .. 0.68

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 1.4e-07
                 EEEEESTTSSHHHHHHHHHT...................STEEESSSTTSSSSEEEEEEEETTEE.................................. CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltg...................ekaivsdkpgtTrdinegrvklkgke.................................. 47 
                  a+ G   +GKS+++  +tg                    ++++s+                  +                                  
  EEA21322.1  46 LAVCGDQSAGKSSVLEGITGipfprqeglctrfpteiilCHSETSQ------------------Qttitasirphssrtkeiqntlasyrkvlqdinel 126
                 6899***************955555555555554433321223333..................03333333333444444556777788888899999 PP

                 .........................................EEEEECGGCSS.......HHHHHH......HHHHHHHHHHCTSEEEEEEETTTTCSHH CS
    MMR_HSR1  48 .........................................ielvDtpGlie.......gaseek......glgkaflaleeadlillvvdaseeklkp 92 
                                                          + +vD+pGlie       +    +      ++  a+l+  +  +il vv+as++  ++
  EEA21322.1 127 psviqevskrmeirgytedgnglafapdalrieitgpiglhLSVVDLPGLIEvpddnrdD----EdvnavmDMVTAYLESSR-TIILAVVQASNDVATQ 220
                 999999999****************************************99666544321....223435567777777666.8999999988553333 PP

                 HHHH CS
    MMR_HSR1  93 ldee 96 
                 +  +
  EEA21322.1 221 KIIR 224
                 3333 PP

>> GED  Dynamin GTPase effector domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0       0.9   3.2e+03       5      20 ..     105     120 ..     102     131 .. 0.68
   2 !   15.2   0.2     5e-06     0.018       6      89 ..     624     707 ..     620     709 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.9
                 XTTHHHHHHHHHHHHH CS
         GED   5 eveeirslvksYfniv 20 
                  ++ei++ + sY ++ 
  EEA21322.1 105 RTKEIQNTLASYRKVL 120
                 5677777777776654 PP

  == domain 2  score: 15.2 bits;  conditional E-value: 5e-06
                 TTHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHTHHHHCCCCCHHHCCTTSGGGHHHHT---SCHCCCCHHHHHHHHHHHHHCCCC CS
         GED   6 veeirslvksYfnivrktiadqiP.kaimhllvneakeslqkellakLykkedldeLLkEdeeiaekRkelkkrlealkkAreil 89 
                 ++e  + +++Y++++ kt  d++  ++i  +++  + + +    +a+L ++e   ++ +E ++ ae+R++l+++ +al+++   l
  EEA21322.1 624 CKEALTQLNAYYKVAMKTFTDNVTrQVIERHMISPLPQAFCPTSIAQLSDEEL-LRIGSEPNHEAERRTKLANMAQALRQSLVDL 707
                 55666789*************997368889********************996.569**********************987655 PP

>> PriX  Primase X
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       1.9   6.8e+03      50      98 ..      85     133 ..      81     134 .. 0.75
   2 ?    0.1   0.1      0.29     1e+03       2      45 ..     505     551 ..     504     588 .. 0.67
   3 ?   10.1   0.0   0.00022       0.8      17      87 ..     605     674 ..     590     679 .. 0.83

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 1.9
                 ..TTSSSS---HHHHHHHHHHHHHHT-----HHHHHHH-HHHHHHHHHH CS
        PriX  50 ckkkknlskiyeswirsvikgvkekglkpislkklkekdkelyeviekv 98 
                 c+ ++  +    + ir   ++ ke + +  s++k+ ++ +el +vi++v
  EEA21322.1  85 CHSETSQQTTITASIRPHSSRTKEIQNTLASYRKVLQDINELPSVIQEV 133
                 6666666667777788888888888888889999988888888888876 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.29
                 HHHHHHHHH--...SSTHHHHHHHTHHHHHHHTS---HHHHHHHHHH CS
        PriX   2 eWiekvlekgl...pDgRkrlilyvisrYLvnvkklseeealkklke 45 
                 +W ekv+++ +   +Dg +r +  ++   L n  kl  ee  k l++
  EEA21322.1 505 QWTEKVVKNVVredEDGLRREVGSILQDSLDNCEKLALEELNKLLED 551
                 69999999988444467777777777778888887777776666554 PP

  == domain 3  score: 10.1 bits;  conditional E-value: 0.00022
                 HHHHHHTHHHHHHHTS---HHHHHHHHHHHH....TTSSSS---HHHHHHHHHHHHHHT-----HHHHHHH CS
        PriX  17 krlilyvisrYLvnvkklseeealkklkeflksckkkknlskiyeswirsvikgvkekglkpislkklkek 87 
                 +r+i  v sr +v++ +   +eal +l+ ++ +   k+ ++++ +  i+  +     + + p+s+ +l ++
  EEA21322.1 605 ERFISAVESRIIVDMDEQACKEALTQLNAYY-KVAMKTFTDNVTRQVIERHMISPLPQAFCPTSIAQLSDE 674
                 79*****************************.666677778888888877666666688888888888654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (712 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       855  (0.0476881); expected 358.6 (0.02)
Passed bias filter:                      497  (0.0277205); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.67u 0.31s 00:00:00.98 Elapsed: 00:00:00.47
# Mc/sec: 4523.96
//
Query:       EEA21323.1  [L=379]
Description: hypothetical protein PMAA_051330 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.6e-23   83.7   0.0    8.5e-15   55.2   0.0    2.1  2  Abhydrolase_2  Phospholipase/Carboxylesterase
    0.00033   20.2   0.0     0.0008   18.9   0.0    1.6  1  Peptidase_S9   Prolyl oligopeptidase family
    0.00085   19.4   8.4     0.0011   19.1   8.4    1.1  1  TFIIA          Transcription factor IIA, alpha/beta subunit
  ------ inclusion threshold ------
      0.014   16.0   0.0      0.054   14.1   0.0    1.8  2  Abhydrolase_6  Alpha/beta hydrolase family
      0.058   12.7   0.1       0.13   11.5   0.0    1.6  2  Hydrolase_4    Serine aminopeptidase, S33
       0.37    8.9  16.8       0.49    8.5  16.8    1.1  1  Nop14          Nop14-like family
        2.8    7.2  15.7        3.7    6.8  15.7    1.1  1  BUD22          BUD22
        4.1    6.9  14.9        6.1    6.3  14.9    1.2  1  PPP4R2         PPP4R2


Domain annotation for each model (and alignments):
>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.2   0.0   3.8e-18   8.5e-15      12     150 ..      22     179 ..      13     185 .. 0.83
   2 !   26.5   0.0   2.2e-09     5e-06     155     215 ..     307     369 ..     293     371 .. 0.88

  Alignments for each domain:
  == domain 1  score: 55.2 bits;  conditional E-value: 3.8e-18
                    ---EEEEEE--TT--S....HHHHHHHH.TT--TTEEEEEE---EEE-GGGTT-EEE-SS-B--SSTTS...-B-HHHHHHHHHHHHHHHHHHHHT CS
  Abhydrolase_2  12 kaqavviflHGlGdsg....hawaeaakteaalpnikfifphgpelpvtlnggmrmpaWfdlvglspek...kedeagikksaekleelidaelkk 100
                    k++++ i lHG G++g        +  +  a+lp +kf+fp ++++ +t+  +    +Wfd + l++ +     + +g +++a+ l eli++e + 
     EEA21323.1  22 KHTHTFIVLHGRGSNGerfgCELLDSVNLRARLPTVKFVFPTASKRRSTVLKKIPINQWFDNYCLDDPNqrtDLQVEGLMETAQFLRELINNEAHI 117
                    8999************76665556788889**********************************998774443455699*************9877 PP

                    T......--GGGEEEEEETHHHHHHHHHHH......T-SS--SEEEEES---TTGGGTTTTS CS
  Abhydrolase_2 101 g......ipssriiigGFSqGaalalylal......tlpkklggivafsgalplsqklessa 150
                               r+i+gG SqG+a a+ + l      + +++ g  +++sg+lp +++l+s +
     EEA21323.1 118 LsdgtgeSGYRRVILGGLSQGCAAAVFTLLgggigeSGNERPGAFFGMSGWLPFEKQLNSMM 179
                    77778888899**************999883333323344889999*******999999754 PP

  == domain 2  score: 26.5 bits;  conditional E-value: 2.2e-09
                    GG-EEEEEEETT-SSS-HHHHHHHHHHHHTTS-.GEEEEEETT--SS.--HHHHHHHHHHHHH CS
  Abhydrolase_2 155 kklpilqiHgeeDpvvplalgkaakevlkkllk.kvelksyeglaHs.ideeemqdikeflkk 215
                     ++pi+++Hg+ Dp v + lg ++ e+l+k l+ +v+ k yeg +H   +++e+ d+ +fl+ 
     EEA21323.1 307 LQTPIFLGHGSADPKVSVHLGDKMVELLSKRLEmDVTWKAYEGFGHWyKVPDEIDDVLDFLRQ 369
                    479*******************************************625789*******9986 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.0   3.6e-07    0.0008     141     209 ..     302     371 ..     259     373 .. 0.81

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 3.6e-07
                   -....---EEEEEEETT-SSS-THHHHHHHHHHH--S-S.EEEEEETTS-SSTTSSHHHH.HHHHHHHHHHHHHC CS
  Peptidase_S9 141 k....aypplLlihGlaDdrvppaealklvaaLqkkgkn.vlllifpdegHgvgkprakv.eelarllaFlkeal 209
                   +     ++p++l hG aD +v +  + k+v+ L k+ +  v ++ + + gH+++     v +e+ ++l+Fl +++
    EEA21323.1 302 EtfptLQTPIFLGHGSADPKVSVHLGDKMVELLSKRLEMdVTWKAYEGFGHWYK-----VpDEIDDVLDFLRQNV 371
                   1445679***************************666666***********887.....4489999999998876 PP

>> TFIIA  Transcription factor IIA, alpha/beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   8.4   4.9e-07    0.0011     309     372 ..     174     235 ..      88     240 .. 0.76

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 4.9e-07
       TFIIA 309 dlseilqlDGagddsdeeeeeeesdedsdsessdd.edeqveEDplNSdDDvddeddddlfdtdn 372
                 +l++++ +DG   dsd+e+e +     + ++s++d + +++ E+   SdDD++de+d++++d ++
  EEA21323.1 174 QLNSMMNVDGIINDSDDEKEADGL---DHQDSEHDgDGKEESEENESSDDDEEDEEDEEIDDRSD 235
                 7899******88888883322222...33334445244446788889************999887 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   2.4e-05     0.054       2      81 ..      28     144 ..      27     204 .. 0.72
   2 ?   -0.4   0.0      0.67   1.5e+03     142     198 ..     280     338 ..     224     366 .. 0.55

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 2.4e-05
                    EEE--GC.....G....C.HHHHHHHHCCT..C.....................EEEEE--TTSTS-GGCS--HHHCHHH.HHHHCCTT....... CS
  Abhydrolase_6   2 lllHGagssassW....l.vapLaallaag..v.....................hvlapDlpGhGrsdpppldledladl.aalldelaa...... 62 
                    ++lHG gs+++ +    l  ++L+a+l+    v                      ++++D p++ r+d    +l + a++ ++l++ +a+      
     EEA21323.1  28 IVLHGRGSNGERFgcelLdSVNLRARLPTVkfVfptaskrrstvlkkipinqwfDNYCLDDPNQ-RTDLQVEGLMETAQFlRELINNEAHilsdgt 122
                    789**99999999987525556666666666423334444444444445555557778888888.4666666665544445556666655889999 PP

                    ....TTSEEEEEETCHHHHHHH CS
  Abhydrolase_6  63 ...gggpvvlvGHSlGGalala 81 
                       g+++v+l G S+G+a a +
     EEA21323.1 123 gesGYRRVILGGLSQGCAAAVF 144
                    9***************998877 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.67
                    CCHCHCCCGHHHHCCHHCHTTCCHHTT-TTGCEEE..CTT-C..HHHHCHHCCCH.STTEEE CS
  Abhydrolase_6 142 aawrarlarlaallaglgllpaaawadlpvpllvl..ggeDp..lvprllerlla.qagarl 198
                     + +++l ++++ l+    +  + +++l +p++ l  g++Dp  +   +l + ++ + ++rl
     EEA21323.1 280 SSITDALNHVRDILDLEPIFISETFPTLQTPIF-LghGSADPkvS--VHLGDKMVeLLSKRL 338
                    344444444444444344444777777788874.42447777442..224444444333333 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.1       2.5   5.7e+03       4      20 ..      24      40 ..      22      41 .. 0.80
   2 ?   11.5   0.0   5.9e-05      0.13     185     232 ..     302     352 ..     286     354 .. 0.89

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 2.5
  Hydrolase_4  4 kavvvlvHGlaehsgry 20
                  ++ +++HG+++  +r+
   EEA21323.1 24 THTFIVLHGRGSNGERF 40
                 5788999**99988876 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 5.9e-05
  Hydrolase_4 185 eraakitlPllllhGeaDkvvdpeasrelyerlgsk...dktlklypglyH 232
                  e  + +++P++l hG+aD+ v+     +++e l+++   d+t k y+g+ H
   EEA21323.1 302 ETFPTLQTPIFLGHGSADPKVSVHLGDKMVELLSKRlemDVTWKAYEGFGH 352
                  6667899*******************8888888887778**********99 PP

>> Nop14  Nop14-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5  16.8   0.00022      0.49     351     419 ..     187     258 ..     169     300 .. 0.43

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00022
       Nop14 351 deddfeedddlveseseeee...eeeeedeeeeedeeeeeeeeededdlsdlese.....eeeeedeleeelleeek 419
                 d+dd++e d l++++se +    ee+ee+e++++dee+  ee+e+ dd sd +       ++ e+d +    l++e+
  EEA21323.1 187 DSDDEKEADGLDHQDSEHDGdgkEESEENESSDDDEED--EEDEEIDDRSDIDRAnsisfSDAESDAFV---LHTED 258
                 22333333333333333333211222222222222222..22233333333332223444445555442...22222 PP

>> BUD22  BUD22
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8  15.7    0.0017       3.7     166     221 ..     191     265 ..     171     310 .. 0.38

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0017
       BUD22 166 eeesdkeeesedsed.eekeeseddeeeeeededdedaee..................deedeeaeerelaqydg 221
                 e+e+d  + ++++ d + keese++e++++++ed+ed+e                   +++    +e+++a++d 
  EEA21323.1 191 EKEADGLDHQDSEHDgDGKEESEENESSDDDEEDEEDEEIddrsdidransisfsdaeSDAFVLHTEDNFASFDP 265
                 112222222222222111111111111111111111111111111111112222222111111122222222222 PP

>> PPP4R2  PPP4R2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3  14.9    0.0027       6.1     200     260 ..     170     232 ..     165     258 .. 0.49

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0027
      PPP4R2 200 pfikeidsimsvnlgfedeeekeedd...neseesaseseeiteekdesvkveekdddeeddee 260
                 pf+k+++s+m+v    +d+++++e d   ++++e + + +e++ee+++s++ ee d+++e+ ++
  EEA21323.1 170 PFEKQLNSMMNVDGIINDSDDEKEADgldHQDSEHDGDGKEESEENESSDDDEE-DEEDEEIDD 232
                 788888888887766555555555333323333333333333333333333333.222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (379 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       907  (0.0505884); expected 358.6 (0.02)
Passed bias filter:                      604  (0.0336884); expected 358.6 (0.02)
Passed Vit filter:                       121  (0.00674884); expected 17.9 (0.001)
Passed Fwd filter:                        22  (0.00122706); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.42
# Mc/sec: 2709.54
//
Query:       EEA21324.1  [L=179]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (179 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1050  (0.0585643); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 1200.93
//
Query:       EEA21325.1  [L=1129]
Description: DEAD box helicase Mph1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      1e-19   70.9   0.3    5.4e-19   68.6   0.1    2.2  2  Helicase_C     Helicase conserved C-terminal domain
    4.6e-19   69.1   0.0    9.5e-19   68.0   0.0    1.5  1  ResIII         Type III restriction enzyme, res subunit
    1.3e-14   54.4   0.0    3.4e-14   53.0   0.0    1.7  2  DEAD           DEAD/DEAH box helicase
  ------ inclusion threshold ------
      0.023   14.4   0.0      0.046   13.4   0.0    1.4  1  SWI2_SNF2      SWI2/SNF2 ATPase
      0.025   13.8   0.0      0.047   12.9   0.0    1.3  1  ERCC3_RAD25_C  ERCC3/RAD25/XPB C-terminal helicase
      0.051   13.5   0.4       0.15   12.0   0.4    1.9  1  UIM            Ubiquitin interaction motif
       0.09   13.1   0.0       0.27   11.5   0.0    1.8  1  AAA_22         AAA domain
        6.3    7.5   5.4         17    6.1   0.0    3.6  3  OAD_gamma      Oxaloacetate decarboxylase, gamma chain


Domain annotation for each model (and alignments):
>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0       1.2   2.8e+03      55     102 ..     433     487 ..     417     493 .. 0.56
   2 !   68.6   0.1   2.4e-22   5.4e-19      15     110 ..     664     769 ..     646     770 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 1.2
                 HHHHHHHHHTTSSSEEEESGGGTS..........SSTSTTESEEEESSSSSSHHHHHH CS
  Helicase_C  55 reeileqfnkgesdvLiatdvaer..........GidipkvnlVinfdlprnvtsyiq 102
                   + l++fn+ +++vL  t   +           G+di +  + i+ +   ++++y++
  EEA21325.1 433 VVKFLRRFNQ-SFRVLALTATPGStveavqavidGLDIAR--VEIRTEQSLDIRQYVH 487
                 5567888854.88888777652222333333333555533..3344444444555555 PP

  == domain 2  score: 68.6 bits;  conditional E-value: 2.4e-22
                 TTSEEEEEESSHHHHHH.HHHHHHHT.........TSTEEEESTT........STHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSS CS
  Helicase_C  15 eggkilifvntidrlek.vklllekk.........gikvavlhge........lpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlpr 95 
                 ++ +++if++++d++e+ +++l++++         g        +        + q+ ++ ++e+f++g+++ ++at+++e+G+di +v+l++ +d   
  EEA21325.1 664 SNTRVMIFAHFRDSAEEiTRVLKRQEpiirphvfvG--------QanakgsegMDQKTQLSVIEKFKNGTYNTIVATSIGEEGLDIGEVDLIVCYDSSA 754
                 6889*********99998888877778665544443........444445555********************************************** PP

                 SHHHHHHHHTTSSST CS
  Helicase_C  96 nvtsyiqriGRtgRa 110
                 ++ ++ qr+GRtgR 
  EEA21325.1 755 SPIRMLQRMGRTGRK 769
                 **************6 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.0   0.0   4.3e-22   9.5e-19      26     169 ..     311     453 ..     260     455 .. 0.86

  Alignments for each domain:
  == domain 1  score: 68.0 bits;  conditional E-value: 4.3e-22
                 EEEEEESTTSTHHHHHHHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG.......GEEEESSS-B--.......-SEEEEEHHHHHHTH... CS
      ResIII  26 rglikmaTGtGKTlvaaklierllkkgkeekflflvprkslleqtleefkkflseayke...igkkvsgdkkkakekdstnkkilvttiqsldadseee 121
                 ++l++++TG GKT++aa ++ + +++ k  +++f +p+k l++q   +   ++  ++++    +++v   ++ +   + ++k+++++t q+l +d+   
  EEA21325.1 311 NLLVALPTGLGKTFIAATVMLNWFRWTKDAQIVFTAPTKPLVSQQVAACLGIAGIPRSDttlLTGNVPPGTRAE---EWQTKRVFFMTPQTLINDL--- 403
                 789*************************************************9999887666555555555555...79*****************... PP

                 .....HHHTTT-SEEEEETGGGTTS.TTTHHHHHT-....--SEEEEEESS- CS
      ResIII 122 eeeseellrdrfdviiiDEaHrlgakkswreilekf....keavllglTATp 169
                   ++  ++++r+ ++++DEaHr+++  ++ e+++ +    +++ +l+lTATp
  EEA21325.1 404 --KTGIADPKRIVLLVVDEAHRATGGYAYVEVVKFLrrfnQSFRVLALTATP 453
                 ..899999*****************9999998555422236699*******9 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.0   0.0   1.5e-17   3.4e-14      16     174 ..     311     458 ..     298     460 .. 0.90
   2 ?   -3.3   0.0         3   6.7e+03      44      94 ..     662     718 ..     654     734 .. 0.54

  Alignments for each domain:
  == domain 1  score: 53.0 bits;  conditional E-value: 1.5e-17
                 EEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTCSEEEEEHHHHHHHHHC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  16 dvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngvdivvgtpgrlddllst 114
                 ++lva +TG GKT +++  +l+++   + ++  ++++ +Pt+ L+ q++  +  +    +  + l++g+v+     ++  ++ +++++tp+ l++ l+t
  EEA21325.1 311 NLLVALPTGLGKTFIAATVMLNWF---RWTKDAQIVFTAPTKPLVSQQVAACLGIAGIPRSDTTLLTGNVPPGTRAEEW-QTKRVFFMTPQTLINDLKT 405
                 789********************9...568888*******************99999766778899*************.99***************** PP

                 TSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD 115 gklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlpkdvk 174
                 g  + +++ +lV+DEa+r        ++ + l+++       +++ +v++l+AT+ ++v+
  EEA21325.1 406 GIADPKRIVLLVVDEAHRATGGYAYVEVVKFLRRF-------NQSFRVLALTATPGSTVE 458
                 *********************97777777778888.......45677*******998887 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 3
                 TSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEET........TSSHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxxx RF
        DEAD  44 gktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliig........gvaardqlskl 94 
                 g+++++++i +  r  ae++ + lk+    i+   ++++g        g +++ qls++
  EEA21325.1 662 GTSNTRVMIFAHFRDSAEEITRVLKRQEPIIR--PHVFVGqanakgseGMDQKTQLSVI 718
                 55566777777777777777777776666433..3333332222222245555555555 PP

>> SWI2_SNF2  SWI2/SNF2 ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0     2e-05     0.046     114     159 ..     406     455 ..     366     471 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 2e-05
   SWI2_SNF2 114 evlsereniivlvDEaHRsqyg....elakklrkalpnaafigFTGTPil 159
                    + ++ ++++vDEaHR   g    e+ k lr++ +   ++++T TP +
  EEA21325.1 406 GIADPKRIVLLVVDEAHRATGGyayvEVVKFLRRFNQSFRVLALTATPGS 455
                 4556667778889******99988889999******************65 PP

>> ERCC3_RAD25_C  ERCC3/RAD25/XPB C-terminal helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   2.1e-05     0.047      90     154 ..     710     772 ..     702     790 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.1e-05
  ERCC3_RAD25_C  90 seaerlkilqkfkknpkvntiflskvgDtsiDlPeanvliqisshfgsrrqeaqrlGriLrakkk 154
                    +++ +l++++kfk+  ++nti+   +g++ +D+ e   ++  +s ++  r   qr+Gr  r +++
     EEA21325.1 710 DQKTQLSVIEKFKNG-TYNTIVATSIGEEGLDIGEVDLIVCYDSSASPIR-MLQRMGRTGRKRAG 772
                    6788899*****976.89*******************9999988766555.68*****9887765 PP

>> UIM  Ubiquitin interaction motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.4   6.9e-05      0.15       1      15 [.     153     167 ..     153     169 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 6.9e-05
         UIM   1 dEdedLqrAlalSlq 15 
                 ++d+dL++A++ Sl 
  EEA21325.1 153 EDDDDLRAAIEASLH 167
                 69***********95 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   0.00012      0.27      13     116 ..     317     441 ..     311     455 .. 0.65

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00012
      AAA_22  13 esGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelka...............erlsseellealeqalrarav..... 91 
                 ++G GKT+ +++++ +  ++      ++ ++ +t+p +   ++   + l + g ++++               e+++++ ++ + +  +++ ++     
  EEA21325.1 317 PTGLGKTFIAATVMLNWFRWT-----KDAQIVFTAPTKPLVSQQVAACLGIAGIPRSDttlltgnvppgtraeEWQTKRVFFMTPQTLINDLKTgiadp 410
                 789999999999876654554.....4444544555444444444555555555555556666666666667755555555566666666666666789 PP

      AAA_22  92 ..ielliiDEaqhlrs.....eealeeLrsll 116
                   i+ll++DEa++  +      e++++Lr++ 
  EEA21325.1 411 krIVLLVVDEAHRA-TggyayVEVVKFLRRFN 441
                 99***********9.33567899999997764 PP

>> OAD_gamma  Oxaloacetate decarboxylase, gamma chain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.0    0.0078        17      53      75 ..     142     168 ..     123     170 .. 0.66
   2 ?    0.2   0.3      0.52   1.2e+03      39      56 ..     890     907 ..     882     929 .. 0.43
   3 ?    0.4   0.2      0.44   9.9e+02      26      52 ..    1007    1033 ..    1003    1069 .. 0.61

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0078
   OAD_gamma  53 aaaaa....eldddeelvAvIaaAiaa 75 
                 +++++      +dd++l A+I a ++ 
  EEA21325.1 142 TPQTTtrnaTTEDDDDLRAAIEASLHS 168
                 222223455789***********9997 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.52
   OAD_gamma  39 kkkkakaaaaaaaaaaaa 56 
                 ++kk +++++++++++ a
  EEA21325.1 890 SAKKIEPKKRKTPPKPVA 907
                 222222222222222222 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.44
   OAD_gamma   26 slfskiikkkakkkkkkakaaaaaaaa 52  
                  + +s +++kk+ k++  +++++ ++++
  EEA21325.1 1007 KQVSTVSNKKSRKPTTSEAPKPTKNNV 1033
                  445555555555555444444444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1129 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       525  (0.0292822); expected 358.6 (0.02)
Passed bias filter:                      350  (0.0195214); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.82u 0.29s 00:00:01.10 Elapsed: 00:00:00.47
# Mc/sec: 7158.47
//
Query:       EEA21326.1  [L=267]
Description: F-actin capping protein beta subunit [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.1e-105  352.5   0.0   1.3e-105  352.3   0.0    1.0  1  F_actin_cap_B  F-actin capping protein, beta subunit
  ------ inclusion threshold ------
      0.066   12.6   0.0       0.19   11.2   0.0    1.8  2  F-actin_cap_A  F-actin capping protein alpha subunit


Domain annotation for each model (and alignments):
>> F_actin_cap_B  F-actin capping protein, beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  352.3   0.0  1.5e-109  1.3e-105       1     238 []       6     238 ..       6     238 .. 0.98

  Alignments for each domain:
  == domain 1  score: 352.3 bits;  conditional E-value: 1.5e-109
  F_actin_cap_B   1 ldaaldllrrlppkkveknlenlielvpdlaedllssvdqplkvakdkeegkeyllcdyNrdgdsYRSpwsnkYdpeledglvpseklrklEiean 96 
                    +d+aldllrrl p+++ knl+++++lvpdl+edll svdqpl+v+++ +++++yllcdyNrdgdsYRSpwsn++dp++edg+vpse++rklE++an
     EEA21326.1   6 FDSALDLLRRLSPRDTGKNLQSITNLVPDLTEDLLASVDQPLEVRRCLKSNRDYLLCDYNRDGDSYRSPWSNEFDPPIEDGTVPSERVRKLEVAAN 101
                    689********************************************************************************************* PP

  F_actin_cap_B  97 eafdeYrelYYeggvssvYlwdlddegfagvvllkkeakeskeekkgswdsihvvevkeeesskkkaeYkltstvilslkkkkkkagelslsgslt 192
                    eafd+YrelYYeggv svY+wdldd gfagvvllkk +++   +++g+wdsihv+e++++   ++ ++Ykltstvil+l++++++ ge++lsg++t
     EEA21326.1 102 EAFDVYRELYYEGGVGSVYFWDLDD-GFAGVVLLKKGVTPGG-KSSGAWDSIHVFEATDR---ARMTHYKLTSTVILHLSNESDALGEMNLSGNMT 192
                    ************************9.************9888.9*************999...5679***************************** PP

  F_actin_cap_B 193 rqlekelkledesshianiGklvedmenklrnllqevYfgktkdiv 238
                    rq+e++l++e ++sh+an+G+lvedme k+rnllqevYfgk+kd+v
     EEA21326.1 193 RQVEADLPFESDASHVANVGRLVEDMELKMRNLLQEVYFGKAKDVV 238
                    ********************************************97 PP

>> F-actin_cap_A  F-actin capping protein alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   2.1e-05      0.19      99     246 ..      91     247 ..      53     253 .. 0.81
   2 ?    1.6   0.0     0.017   1.5e+02       3      32 ..     224     253 ..     222     262 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 2.1e-05
                    GGGHHHHHHHHHHHHHHHHHH-TT-EEEEEEEEETTEEEEEEEEEEEEEEGGGTEEEEEEEEEEEE......SSEEEEEEEEEEEE....EE-SSE CS
  F-actin_cap_A  99 seleelrkalekalekYvkehYpsgvasvypkeeeeekelaiiivgnkynpsnFwnGrwrseytvd......sssktleGkikvqv....HYyEdG 184
                    + + +l  a ++a++ Y + +Y+ gv svy  + +++    +++ ++ + p    +G w s  +++      +++ +l++++ +++        + 
     EEA21326.1  91 ERVRKLEVAANEAFDVYRELYYEGGVGSVYFWDLDDGF-AGVVLLKKGVTPGGKSSGAWDSIHVFEatdrarMTHYKLTSTVILHLsnesDALGEM 185
                    567788889999*****************876655555.7999999******************99888866556666666666553333445567 PP

                    EEEEEEEEEEEEEEE--SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTTTS-SS-T CS
  F-actin_cap_A 185 NVqlktskevseslsvsseessakeivklikeaenkyqeeLnesyeeLsekafkaLRRqLPv 246
                    N + +++++v+++l+++s+ s   ++ +l++++e k+ + L+e y   ++    +LR   P+
     EEA21326.1 186 NLSGNMTRQVEADLPFESDASHVANVGRLVEDMELKMRNLLQEVYFGKAKDVVGDLRSIAPL 247
                    99999**************************************9987777777777766665 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.017
                    HHHHT--TT-HHHHHHHHHCC-S-CCCCTT CS
  F-actin_cap_A   3 slllqsPpgelneVlkDlrallsddsklee 32 
                    +ll++   g++++V+ Dlr++   +++ +e
     EEA21326.1 224 NLLQEVYFGKAKDVVGDLRSIAPLSETNQE 253
                    788888899************953333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (267 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       425  (0.0237046); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.29s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 1862.14
//
Query:       EEA21327.1  [L=175]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.8e-44  150.5   0.2    4.6e-44  150.2   0.2    1.1  1  Med11     Mediator complex protein


Domain annotation for each model (and alignments):
>> Med11  Mediator complex protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  150.2   0.2   2.6e-48   4.6e-44       1     137 []      14     158 ..      14     158 .. 0.93

  Alignments for each domain:
  == domain 1  score: 150.2 bits;  conditional E-value: 2.6e-48
       Med11   1 aeriqqLneIDkdIvslLesasealkaLskpp.eqepaseseeaqkeafkaatstffstLssvdvrLrrqIyaLeeagiitlessaaasagksaa.... 94 
                 a+ri+qLneIDkdI++l +sa+ a++aL++++ +++++ +s  ++k+afk++ts++fs+Lss+dvrLrrq+yaLeeagi ++ess+a++ + +++    
  EEA21327.1  14 ADRIRQLNEIDKDIAKLVNSAGLAIQALTNAKnTETTTGNSVAERKAAFKDSTSQYFSLLSSIDVRLRRQVYALEEAGILEAESSTATNVSFKNDtttt 112
                 69****************************99778888899*******************************************999988877777888 PP

       Med11  95 ...karlepsgvgavgnldvgwlnsrsskverdmeaelwaearelL 137
                    +++  +   g+ + l+++wlnsr+++v++d+eae wa are+L
  EEA21327.1 113 tgtGPGGTGTAAGTFNPLEISWLNSRKDTVGKDKEAESWAAAREFL 158
                 877666667777********************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (175 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       706  (0.0393775); expected 358.6 (0.02)
Passed bias filter:                      414  (0.0230911); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.44
# Mc/sec: 1187.94
//
Query:       EEA21328.1  [L=749]
Description: transcription initiation factor TFIID subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.7e-43  145.1  22.8    5.7e-09   36.5   0.1    6.8  6  WD40         WD domain, G-beta repeat
    8.6e-41  139.2   0.1    1.3e-40  138.7   0.1    1.2  1  TFIID_NTD2   WD40 associated region in TFIID subunit, NTD2 do
    4.4e-10   39.7   0.5      0.011   16.0   0.0    4.8  5  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
    6.5e-07   29.1   0.0    1.6e-06   27.8   0.0    1.7  1  LisH         LisH
    0.00017   20.4   1.1       0.17   10.5   0.0    3.3  3  Nup160       Nucleoporin Nup120/160
  ------ inclusion threshold ------
        0.1   13.0   0.0       0.23   11.9   0.0    1.5  1  DUF4550      Domain of unknown function (DUF4550)


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.1   1.8e-05     0.053       7      38 .]     388     422 ..     383     422 .. 0.80
   2 !   19.5   0.0   4.4e-07    0.0013       7      38 .]     448     492 ..     442     492 .. 0.72
   3 !   30.4   1.0   1.6e-10   4.7e-07       1      37 [.     496     533 ..     496     533 .. 0.97
   4 !   36.5   0.1   1.9e-12   5.7e-09       3      37 ..     540     575 ..     538     575 .. 0.95
   5 !   25.4   0.1   5.9e-09   1.8e-05       2      38 .]     581     618 ..     580     618 .. 0.93
   6 !   30.6   0.5   1.4e-10   4.2e-07       2      38 .]     623     661 ..     622     661 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.8e-05
                 EESSSS....EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   7 ltGHss....vtslafspdgawlasGsdDgtvriWd 38 
                 +t H+     + + +fs+d+ ++a+G +D  +r+W+
  EEA21328.1 388 FTFHNTydrmI-CTDFSDDNMLVAAGFEDSYIRVWS 422
                 44573346778.8899*******************5 PP

  == domain 2  score: 19.5 bits;  conditional E-value: 4.4e-07
                 EESS.SSEEEEE............EETTSSEEEEEETTSEEEEEE CS
        WD40   7 ltGH.ssvtsla............fspdgawlasGsdDgtvriWd 38 
                 l GH ++v++++             + + +wl+s+s D+t+r+W+
  EEA21328.1 448 LFGHsGPVYAVKfapsaqrsesemAPTNARWLLSSSADKTIRLWS 492
                 459*777*****5555555555555555556999999*******5 PP

  == domain 3  score: 30.4 bits;  conditional E-value: 1.6e-10
                 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 
                 +qc+ +++GH ++v++l++ p g +++sG+ D+t r+W
  EEA21328.1 496 WQCMVVYKGHdQPVWDLSWGPFGYYFVSGGHDKTARLW 533
                 79********888****************99******* PP

  == domain 4  score: 36.5 bits;  conditional E-value: 1.9e-12
                 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   3 clrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 
                 ++r++ GH ++v +++f+p++a++++Gs D+tvr+W
  EEA21328.1 540 QQRIFAGHdQDVDCVCFHPNSAYVFTGSSDRTVRMW 575
                 689*****999****************99******* PP

  == domain 5  score: 25.4 bits;  conditional E-value: 5.9e-09
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 + +r +tGH +++t+la s++g++las++d g++ +Wd
  EEA21328.1 581 NAVRMFTGHtGNITALACSRNGKLLASADDHGSIFLWD 618
                 67899****777*************************9 PP

  == domain 6  score: 30.6 bits;  conditional E-value: 1.4e-10
                 EEEEEEESS.SS.EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ss.vtslafspdgawlasGsdDgtvriWd 38 
                 ++l+  +GH ++ ++sl++s +++ l+s++ D+tvr+Wd
  EEA21328.1 623 RLLKRMRGHgKGgIWSLDWSVESTVLVSSGADNTVRVWD 661
                 6788899**9556**************9989*******9 PP

>> TFIID_NTD2  WD40 associated region in TFIID subunit, NTD2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.7   0.1   4.2e-44   1.3e-40       2     130 .]     100     231 ..      99     231 .. 0.97

  Alignments for each domain:
  == domain 1  score: 138.7 bits;  conditional E-value: 4.2e-44
                 XXXHHHHHHHHHHHHHHHTS-HHHHHHHGGGHHHHHHHHHHHHHHTT-HHHHHHHHHHHGGGGGGGHH.HHHHHTT--SHHHHHHSHHHHHHHHS-EEE CS
  TFIID_NTD2   2 kdpekyekayelLkkwiessldiykpeLsrllyPvFvhlyLelvakgaeeeakkFfekfkedhealhkedlkkLasisspehleenelakafrenkyri 100
                 ++  ky++ ++lLk+wie++ld+ykpeL+r+l+P+Fv+++L+l +  + ++a++Ff++ k+ +  +h+ed+++L++is peh+++n++ak +r nkyri
  EEA21328.1 100 NQRPKYRNGFDLLKNWIEDNLDLYKPELRRVLWPLFVYSFLDLATALYPQDAEQFFSANKNLFLPEHSEDIRSLQKISLPEHVQDNATAKLYRGNKYRI 198
                 67889********************************************************************************************** PP

                 EEEHHHHHHHHHHHHHTT-H...HHHHHHHHHE CS
  TFIID_NTD2 101 klskaafelLlrfLeekeka...vllkilnehl 130
                  ls+ af++L++fLe+k+k+   v+  il++++
  EEA21328.1 199 ILSNPAFSNLMQFLESKSKEggaVMSAILSSYC 231
                 ******************999988888888875 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.51   1.5e+03      46      68 ..     402     424 ..     392     441 .. 0.61
   2 ?    3.0   0.0     0.042   1.3e+02      30      65 ..     496     533 ..     482     537 .. 0.78
   3 !   16.0   0.0   3.8e-06     0.011      22      87 ..     536     596 ..     528     597 .. 0.90
   4 !   15.9   0.0     4e-06     0.012      37      91 ..     589     643 ..     584     644 .. 0.93
   5 !    9.8   0.1   0.00032      0.95       9      67 ..     604     662 ..     604     665 .. 0.87

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.51
  ANAPC4_WD40  46 WkpdgklLavaysdgevrlldae 68 
                  ++ d+ l a +++d+ +r+ +  
   EEA21328.1 402 FSDDNMLVAAGFEDSYIRVWSLD 424
                  44555555666666666655543 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.042
  ANAPC4_WD40  30 wtl..eedkedsevrsLaWkpdgklLavaysdgevrll 65 
                  w+     +++d+ v +L+W p g  ++ + +d + rl 
   EEA21328.1 496 WQCmvVYKGHDQPVWDLSWGPFGYYFVSGGHDKTARLW 533
                  4435545889*******************999988875 PP

  == domain 3  score: 16.0 bits;  conditional E-value: 3.8e-06
  ANAPC4_WD40  22 fRlngqrvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtcl 87 
                   R+  qr++ +    +d+ v +++++p+      + sd +vr+  + +g+ v+ ++ ++ + +t l
   EEA21328.1 536 DRIRQQRIFAG----HDQDVDCVCFHPNSAYVFTGSSDRTVRMWAVTTGNAVRMFTGHTGN-ITAL 596
                  69999****99....9**************************************9988874.7765 PP

  == domain 4  score: 15.9 bits;  conditional E-value: 4e-06
  ANAPC4_WD40  37 edsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgWge 91 
                  + +++++La + +gklLa a + g++ l d   g++++ ++ + +  + +l+W++
   EEA21328.1 589 HTGNITALACSRNGKLLASADDHGSIFLWDLAPGRLLKRMRGHGKGGIWSLDWSV 643
                  6789*************************************999999******86 PP

  == domain 5  score: 9.8 bits;  conditional E-value: 0.00032
  ANAPC4_WD40   9 LiAlatedgellvfRlngqrvwtleedkedsevrsLaWkpdgklLavaysdgevrllda 67 
                  L+A a ++g++ +  l   r+ +  + + ++ + sL W+ + ++L+ + +d++vr+ d+
   EEA21328.1 604 LLASADDHGSIFLWDLAPGRLLKRMRGHGKGGIWSLDWSVESTVLVSSGADNTVRVWDI 662
                  67777788888888888888888888999999***********************9986 PP

>> LisH  LisH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0   5.5e-10   1.6e-06       1      27 []      58      84 ..      58      84 .. 0.98

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 5.5e-10
                HHHHHHHHHHHHHCT-HHHHHHHHHHT CS
        LisH  1 eeLNrLIydYLvkeGyeetAeaFekEa 27
                ++LN+++ dYL k+Gy+ t +++++E+
  EEA21328.1 58 QNLNQIVIDYLAKKGYTRTEAMLRMES 84
                79************************8 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.3   0.1    0.0022       6.5     181     253 ..     430     499 ..     408     503 .. 0.68
   2 !   10.5   0.0   5.6e-05      0.17     220     255 ..     550     585 ..     534     608 .. 0.85
   3 ?    0.7   0.0     0.054   1.6e+02     229     248 ..     644     663 ..     638     696 .. 0.83

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0022
                 EEEEEEE-------B--TTTT.TSS-.-SS---TT-ECEEEEET........TTTEEEEEETT-EEEEEETTTTEEE CS
      Nup160 181 awkesvfepksfllslsgllglladp.srrksgasvalsldvavavvei...gqtylfalsrdgkLrvWnlltgkcl 253
                 a  e v e++s ++ +++l+g ++ p    k ++s    ++ + ++  +   +   l++ s d+++r+W+l+  +c+
  EEA21328.1 430 ATHEGVEEHTSTPSNSKRLFG-HSGPvYAVKFAPS----AQRSESE--MaptNARWLLSSSADKTIRLWSLDLWQCM 499
                 455677889999999999999.4444023233333....2222222..1335899****************977776 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 5.6e-05
                 EEET.....TTTEEEEEETT-EEEEEETTTTEEEEE CS
      Nup160 220 dvavavveigqtylfalsrdgkLrvWnlltgkclat 255
                 dv   + + +++y+f+ s+d+++r+W ++tg  ++ 
  EEA21328.1 550 DVDCVCFHPNSAYVFTGSSDRTVRMWAVTTGNAVRM 585
                 4555556669********************998875 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 0.054
                 TTTEEEEEETT-EEEEEETT CS
      Nup160 229 gqtylfalsrdgkLrvWnll 248
                 ++t+l++   d+++rvW+++
  EEA21328.1 644 ESTVLVSSGADNTVRVWDIA 663
                 5788999999********86 PP

>> DUF4550  Domain of unknown function (DUF4550)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   7.8e-05      0.23      16      58 ..     548     593 ..     544     618 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 7.8e-05
     DUF4550  16 pkkvDvvvfg.svAkvfleseskvvkpwe..eddklwiswthtiei 58 
                  + vD v+f+ ++A vf+ s+ ++v++w+   ++ +++   ht +i
  EEA21328.1 548 DQDVDCVCFHpNSAYVFTGSSDRTVRMWAvtTGNAVRMFTGHTGNI 593
                 5789*****999****************976788888777777666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (749 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       487  (0.0271627); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.67u 0.29s 00:00:00.96 Elapsed: 00:00:00.45
# Mc/sec: 4988.61
//
Query:       EEA21329.1  [L=422]
Description: ribosomal protein/carboxylic ester hydrolase (Ppe1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-20   75.0   0.2    2.2e-20   74.2   0.2    1.3  1  Abhydrolase_6  Alpha/beta hydrolase family
    5.2e-05   23.0   0.1    0.00019   21.2   0.1    1.9  1  Abhydrolase_1  alpha/beta hydrolase fold
  ------ inclusion threshold ------
      0.012   14.9   0.1      0.019   14.3   0.1    1.2  1  Hydrolase_4    Serine aminopeptidase, S33
      0.092   12.5   0.0       0.16   11.7   0.0    1.3  1  Abhydrolase_5  Alpha/beta hydrolase family


Domain annotation for each model (and alignments):
>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.2   0.2   4.9e-24   2.2e-20       1     219 [.     129     386 ..     129     387 .. 0.67

  Alignments for each domain:
  == domain 1  score: 74.2 bits;  conditional E-value: 4.9e-24
                    EEEE--GC.....GC..HHHHHHHHCCT.CEEEEE--TTSTS-.......GGCS--HHH...CHHHHHHHCCTT.......TTSEEEEEETCHHHH CS
  Abhydrolase_6   1 vlllHGagssassWl..vapLaallaag.vhvlapDlpGhGrs.......dpppldled...ladlaalldelaa.....gggpvvlvGHSlGGal 78 
                    +++ HGagss+ s++  ++++++  ++  +  l++D+++hGr+       +p  ld++     +dl+ ++++  +       ++ vlvGHSlGGa+
     EEA21329.1 129 FVMHHGAGSSGLSFAacASEIRKIIPEAgI--LSLDARHHGRTivetrdgSPVQLDYRLetlSQDLLSVIRGTQTqmawdTLPDLVLVGHSLGGAV 222
                    5899**********5578888666666678..*********55554443455556665533235556666666668989878888**********8 PP

                    HHHHHHCC...............EEEEES-..----TTTS----TTHHHHHHTT-C....CCCH...CCH.........S-HSCCCCHHH..C... CS
  Abhydrolase_6  79 alaaapla.............lvvgvlldppptalpagllaaalelllallallrl....lawl...sre.........plprlfladed..a... 140
                     + +a++              +v+g ++d+         l+   +++ ++++++++     +w+   +           ++p ++l +ed  +   
     EEA21329.1 223 ITDVARGGelgtkvlayavldVVEGSAIDA---------LQSMDTYISTRPTRFPSlssaIEWHfrsR-TirnitsariSVP-SLLTEEDnpYdqs 307
                    888444447777666666776666677777.........33333333333333333333344443220.1223333332244.8888777651455 PP

                    .CCCHCHCCCGHHHHCCHHC.HTTCCHHTT-TTGCEEECTT-CHHHHCHHCCCHSTTEEETCE...SSS-HHHHSHHHHHH CS
  Abhydrolase_6 141 .daawrarlarlaallaglg.llpaaawadlpvpllvlggeDplvprllerllaqagarlpvvlpgaGHlphleepdevae 219
                       +wr++la+  +++  ++  l+   +++    ll+l+g+D+l ++l+ + ++  ++ l +vlp aGH++++++p+++a+
     EEA21329.1 308 rPWIWRTNLADTKPFWEDWFkGLSKKFLEAKGGKLLLLAGTDRLDKELMIAQMQ-GKYSL-QVLPLAGHFIQEDQPAKTAR 386
                    58999999999999999888444455555555555777**********998888.*****.*****************997 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.1   4.1e-08   0.00019       1     256 [.     127     380 ..     127     381 .. 0.84

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 4.1e-08
                    SEEEEE-STTTCGGGGTTGHHHHHHHHT..TSEEEEEEETTSTTSSSTTTGB....CHHSHHHHHHHHH.HH......HHHCTTSSEEEEEETHHH CS
  Abhydrolase_1   1 pvlvilhGlpgssdvwaerglapaLakd..gfdvillDlrGvgySspapacin...ddygtasvaddld.ri......ldalgddkltlvGhSmGG 84 
                    p++v++hG + s+ ++a+   a+ + k   ++ ++ lD r +g++    +  +    dy++ ++  dl   i      ++   +  l+lvGhS+GG
     EEA21329.1 127 PLFVMHHGAGSSGLSFAA--CASEIRKIipEAGILSLDARHHGRTIVETRDGSpvqLDYRLETLSQDLLsVIrgtqtqMAWDTLPDLVLVGHSLGG 220
                    689**************9..99999999*****************999998889998999999999999755666334444456789********* PP

                    HHHHHHHHHH..GGGEEEEEEESECSSCCHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHHHHCCSCHHHHHHHHHHHHHH..HCHHHCCHHHHHH CS
  Abhydrolase_1  85 mialayaaey..perVkalvllgaidpaaslieaqrqqaksfpdffdgyaadcarnpagplladelaaleqrhrlvdalkf..pdkskrfpssgsd 176
                    ++ + +a       +V a + l+        +  +  +++s+ ++  +    +   +++  + +++++++  +++  +  +   + +  +++s+++
     EEA21329.1 221 AVITDVARGGelGTKVLAYAVLDV------VEGSAIDALQSMDTYISTRPTRFPSLSSAIEWHFRSRTIRNITSARISVPSllTEEDNPYDQSRPW 310
                    *******98899999*99999999......5555666666666666666666666666666666666666666666666666699999******** PP

                    HCHHHHHHHHHHHHHHHHCCHHHHHHHHHCTHHHHSEEEEEEETTCSSSCHHHHHHHHHCHTSEEEEEEETCSSSHHHHS CS
  Abhydrolase_1 177 nasslatgalksieqwpttdsaklllrlrelknvlaptlvisgtsDplvppkaledlaqllpkkrlvvisdagHlafleg 256
                    +  ++ +  + ++e w   +s k+l   ++      + l+++g +D+l+++ ++ +++++    +l v++ agH+++ + 
     EEA21329.1 311 IWRTNLADTKPFWEDWFKGLSKKFLEAKGG------KLLLLAG-TDRLDKELMIAQMQGK---YSLQVLPLAGHFIQEDQ 380
                    ******************************......8888866.**************88...899**********9875 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.1   4.2e-06     0.019       8      94 ..     130     227 ..     125     244 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 4.2e-06
  Hydrolase_4   8 vlvHGlaehsgryaelaeaLaa..qGfavyalDhrGhGrse.....gkrghvp.sfddyvdDlaafvekvkeehpel...plfllGhSmGGliallyl 94 
                  v+ HG +++   +a  a +  +   +  ++ lD+r hGr+      g  ++++ +++++ +Dl ++++  +++        l+l+GhS+GG++ + ++
   EEA21329.1 130 VMHHGAGSSGLSFAACASEIRKiiPEAGILSLDARHHGRTIvetrdGSPVQLDyRLETLSQDLLSVIRGTQTQMAWDtlpDLVLVGHSLGGAVITDVA 227
                  66788888888888888888774457888999*******99998887777665479999********88887766666789************99887 PP

>> Abhydrolase_5  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   3.6e-05      0.16      53      79 ..     205     231 ..     187     249 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 3.6e-05
  Abhydrolase_5  53 apklekfvvgGhslGGvvasrfaaeee 79 
                     + l+++v+ GhslGG+v++ +a+  e
     EEA21329.1 205 WDTLPDLVLVGHSLGGAVITDVARGGE 231
                    4567789**************998655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (422 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       468  (0.026103); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 2940.63
//
Query:       EEA21330.1  [L=527]
Description: mitochondrial integral membrane protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.6e-84  282.4   2.2    3.8e-84  281.8   2.2    1.2  1  DUF2417        Region of unknown function (DUF2417)
  ------ inclusion threshold ------
       0.08   12.8   4.5        1.3    8.8   0.5    2.5  3  FA_desaturase  Fatty acid desaturase
       0.27   11.0   2.0        0.3   10.9   0.5    1.7  2  Trp_oprn_chp   Tryptophan-associated transmembrane protein (T
        2.9    6.9   5.4        4.6    6.3   5.4    1.2  1  AC_N           Adenylyl cyclase N-terminal extracellular and 


Domain annotation for each model (and alignments):
>> DUF2417  Region of unknown function (DUF2417)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  281.8   2.2   8.4e-88   3.8e-84       1     236 []      33     261 ..      28     261 .. 0.97

  Alignments for each domain:
  == domain 1  score: 281.8 bits;  conditional E-value: 8.4e-88
     DUF2417   1 ErepLLpkqkkshrtigeessegylspddpavspynlwkvrnlrwilnilllinliwlvllLisdFvslpglnnrgsgFndlalillslianllnllff 99 
                 Er++L+++         +++  +ylspddpavspynlw+vr+lr+++ ++l+i+++w+v+lL+s+Fvs+p + nrgsgF+d+++++l++++++++llff
  EEA21330.1  33 ERTRLISRG-------APNEGYRYLSPDDPAVSPYNLWSVRALRFFTCLFLAISFVWWVFLLVSIFVSPPLIYNRGSGFTDFSYTTLTVGNLIVSLLFF 124
                 677777654.......23455667*************************************************************************** PP

     DUF2417 100 glpSkldrvlnivlavLllvnllllllvkytReregfvgiasvlWaaltfllgilldryvekgkkeeeerltgreetrhtlkewlsilvrniikllllv 198
                 ++pSk++ ++n+vla+Lllv+++++l+v+++R +eg+vgias++Wa++++++++++ + vekgk+eeeerltgr etr++l ew+s++v++i+  +++v
  EEA21330.1 125 TIPSKPMIMWNVVLALLLLVDMIIILAVPRIRLEEGWVGIASIVWAVVISVYNVVQVYFVEKGKEEEEERLTGRVETRRSLFEWVSVFVETIVLGIIAV 223
                 *************************************************************************************************** PP

     DUF2417 199 vlilltltllLralDaslespgkfywvdnhkyqlHlkC 236
                 v+illt+tl+Lra Dasle+pgk+y v+n+k+++Hl+C
  EEA21330.1 224 VAILLTATLILRASDASLEAPGKRYLVNNRKFEVHLAC 261
                 ************************************** PP

>> FA_desaturase  Fatty acid desaturase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   0.5    0.0003       1.3     112     166 ..      28      93 ..      22     105 .. 0.75
   2 ?    5.1   0.1     0.004        18     135     211 ..     129     209 ..     110     215 .. 0.66
   3 ?   -3.7   0.0       1.9   8.4e+03     164     187 ..     343     365 ..     334     383 .. 0.67

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0003
  FA_desaturase 112 lvlglwlrrlarrrapsksrrrk............wrllawlllllawlglwlalllllglall.lwl 166
                    ++++  ++rl  r+ap++++r+             w ++a++++ +  l+l++ ++++ +l+++ ++ 
     EEA21330.1  28 HQEPDERTRLISRGAPNEGYRYLspddpavspynlWSVRALRFFTC--LFLAISFVWWVFLLVSiFVS 93 
                    5667788999999999999999999998888886777777777777..88888888887777664433 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.004
  FA_desaturase 135 wrllawlllllawlglwlalllllglall.....lwlvplllllfllalvlnyveHyg....gdwgerqvetsasirsaswllnll 211
                    + +++w+++l+  l+l++ ++  l++        +++++ +++++++++  n+v+ y+    ++ +e ++ ++    ++  l+ ++
     EEA21330.1 129 KPMIMWNVVLA--LLLLVDMIIILAVPRIrleegWVGIASIVWAVVISVY-NVVQVYFvekgKEEEEERLTGRVE--TRRSLFEWV 209
                    55678888888..5555555554444444589988888899999888888.****99966443333333333333..444444444 PP

  == domain 3  score: -3.7 bits;  conditional E-value: 1.9
  FA_desaturase 164 lwlvplllllfllalvlnyveHyg 187
                     w+++ + ++++++++ +   H +
     EEA21330.1 343 PWILVSAGVGSIYSRI-FASRHIH 365
                    6999999999999999.8888887 PP

>> Trp_oprn_chp  Tryptophan-associated transmembrane protein (Trp_oprn_chp)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.5   6.7e-05       0.3      46     150 ..     136     248 ..     129     257 .. 0.68
   2 ?   -3.5   0.0       1.8   7.9e+03     110     127 ..     334     351 ..     317     359 .. 0.56

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 6.7e-05
  Trp_oprn_chp  46 talAlvllAaavAvlavrglgrr..vvgvllalagaga.avaalslltdpadaaraaaaaatgvasaaaave.......ltawpvlalaggvlllla 132
                   + lAl+ll  ++ +lav ++ +    vg+  ++ ++++ +++++++   ++  ++++++ ++ v++     +       + +  vl +++ v++ll+
    EEA21330.1 136 VVLALLLLVDMIIILAVPRIRLEegWVGIASIVWAVVIsVYNVVQVYFVEKGKEEEEERLTGRVETRR---SlfewvsvFVETIVLGIIAVVAILLT 229
                   5699*************998654226777777777655244566666666666666664434443333...23446454444999999999999999 PP

  Trp_oprn_chp 133 gvllllra.rswpamssrY 150
                   + l+l+++ +s +a ++rY
    EEA21330.1 230 ATLILRASdASLEAPGKRY 248
                   9999998845557778888 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 1.8
  Trp_oprn_chp 110 aaaveltawpvlalaggv 127
                   a a +  ++p++ + +gv
    EEA21330.1 334 ALALAGEEGPWILVSAGV 351
                   222223336666666665 PP

>> AC_N  Adenylyl cyclase N-terminal extracellular and transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   5.4     0.001       4.6     209     332 ..     116     241 ..     105     266 .. 0.82

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.001
        AC_N 209 vcvvmlafhaargplevsyvvvlslaillilvlavlcnrnafhqdhmwlacyavilvvlavqvvgvllvqprsas..egiwwtvffiysiytllpvrmr 305
                  ++v l f ++ ++  + + vvl+l +l+ +++++   r  + +  +++a  +  +v+ + +vv v +v        e +   v    s++  + v + 
  EEA21330.1 116 NLIVSLLFFTIPSKPMIMWNVVLALLLLVDMIIILAVPRIRLEEGWVGIASIVWAVVISVYNVVQVYFVEKGKEEeeERLTGRVETRRSLFEWVSVFVE 214
                 5688999999999999**********************************9999999999999999998765544014455567778888888888888 PP

        AC_N 306 aavlsgvllsalhlavslklnaedkfl 332
                 + vl  + + a+ l+ +l l a d  l
  EEA21330.1 215 TIVLGIIAVVAILLTATLILRASDASL 241
                 888888888888888888888887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (527 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1052  (0.0586759); expected 358.6 (0.02)
Passed bias filter:                      564  (0.0314574); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.66u 0.28s 00:00:00.94 Elapsed: 00:00:00.46
# Mc/sec: 3473.89
//
Query:       EEA21331.1  [L=606]
Description: endoplasmic reticulum and nuclear membrane proteinc Npl4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.1e-139  465.0   0.0   1.4e-139  464.7   0.0    1.1  1  NPL4      NPL4 family
    1.3e-68  229.7   0.0    2.1e-68  229.0   0.0    1.3  1  zf-NPL4   NPL4 family, putative zinc binding region
    0.00016   22.1   0.0    0.00058   20.3   0.0    2.0  1  UN_NPL4   Nuclear pore localisation protein NPL4


Domain annotation for each model (and alignments):
>> NPL4  NPL4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  464.7   0.0  2.3e-143  1.4e-139       1     308 []     290     603 ..     290     603 .. 0.98

  Alignments for each domain:
  == domain 1  score: 464.7 bits;  conditional E-value: 2.3e-143
        NPL4   1 RlgylyGryekydevPlGikavveaiyEPpqedeldgltlledeeekevdeiakklglekvGviftDlldagakdgtvlckRhkdsyflsslEvilaak 99 
                 RlgylyG+ye+y+evPlGikavv+aiyEPpq+de+dg+tl+e+++e+e+de+a+ +gl++vGviftDlld+g++dg+v+ckRh+dsy+lsslE+++a++
  EEA21331.1 290 RLGYLYGTYEEYTEVPLGIKAVVQAIYEPPQVDEVDGITLNEWTNEAEIDEVAQLCGLQRVGVIFTDLLDTGKGDGSVICKRHADSYYLSSLEIVFASR 388
                 9************************************************************************************************** PP

        NPL4 100 lqlkhpnvtkysetgkfsskFvtvvvsgdeegeieiesyqvsneaealvradiiepstdPslayvre......sseerYvpevfYkkkneyglevkena 192
                  q++hp++tk+setg+f+s+Fvt+v+sgde+g+i ++syq+sn+a+++vradiieps+dPs+++v++       s+ rY+pevfY+++neyg++v+ena
  EEA21331.1 389 QQAQHPKATKWSETGRFGSNFVTCVLSGDENGAIAVSSYQASNSAVEMVRADIIEPSADPSVMLVQSeddddlGSKLRYIPEVFYRRINEYGANVQENA 487
                 ******************************************************************98888766667********************** PP

        NPL4 193 kPalPveyLlvslthgfpkepkplFkkkakfpienRealgelqdlkelakylkssa.kkeleealsdfHlllylakleilskeelkllleavkekdeek 290
                 kP++PveyLlv+lthgfp+e++p+F  +++fpienRe++ge+q+l++lak+l ++   +++ +a+sdfHll +l  l+ +++ee+kll+++++++d ++
  EEA21331.1 488 KPSFPVEYLLVTLTHGFPTEESPTF-VDSTFPIENREVIGESQELRTLAKKLVAHGdPNKAIRAVSDFHLLAFLRGLGTFNAEEEKLLCRVATTHDPAE 585
                 *************************.999**********************9998769999************************************** PP

        NPL4 291 llelvesegwktlltile 308
                  ++lv+++gw+tl++il+
  EEA21331.1 586 GMQLVNTSGWATLVAILQ 603
                 ****************96 PP

>> zf-NPL4  NPL4 family, putative zinc binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  229.0   0.0   3.4e-72   2.1e-68       1     145 []     143     287 ..     143     287 .. 0.99

  Alignments for each domain:
  == domain 1  score: 229.0 bits;  conditional E-value: 3.4e-72
     zf-NPL4   1 vkedevDellekqdGkikrkrdeklcrhgekgmceycsplepydeeylkekkikhlsfhaylrklnekknkkesssskiapLeelsykvkkecksghap 99 
                 v+++++D++l+k+dGki+r rd k+crhg+kgmc+yc+plepy  eyl ++kikhlsfh+ylrk+n+++nk e +ss+++pL+e++y+vk++c+sgh++
  EEA21331.1 143 VEQSALDNALDKKDGKIPRPRDIKMCRHGPKGMCDYCMPLEPYAPEYLGDRKIKHLSFHSYLRKINSSTNKPELKSSYMPPLSEPYYRVKRDCPSGHPQ 241
                 7899*********************************************************************************************** PP

     zf-NPL4 100 wPkgicskcqPsaitlqrqkfRmvDhvefesseivdkfldaWRktg 145
                 wP+gic+kcqPsaitl+ q+fRmvDhvef+s+++++ +ld+WRk+g
  EEA21331.1 242 WPEGICTKCQPSAITLKPQEFRMVDHVEFSSPSLINGLLDFWRKSG 287
                 ********************************************98 PP

>> UN_NPL4  Nuclear pore localisation protein NPL4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0   9.7e-08   0.00058       5      77 ..       7      85 ..       4      88 .. 0.79

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 9.7e-08
                -EEEEEETTEEEEEEE-TTSBHHHHHHHHHHHSS-STT.T-EEESSTT....CGCCCSSS.SSSCCCTCH--TT-EEEE CS
     UN_NPL4  5 iiiRvqSadGikRieisekstlktllekvaeelkfsen.gfslylern....kttelvss.ssksvkevglkhGdmlyL 77
                i++R  S +G  R+++s+++   +l  k+ae+l  +   +  +  ++      +++l ss + +s++ vgl hGd l+L
  EEA21331.1  7 IVLRFESRNGQFRLTVSPSELFTELSAKIAEHLPENTDpNSIVLSNKPigvgGQERLLSSlDGVSIERVGLSHGDKLFL 85
                89*******************************8777633334444322222566666653789**************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (606 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       362  (0.0201908); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 4227.20
//
Query:       EEA21332.1  [L=198]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.9e-08   32.1   0.0    1.2e-07   31.7   0.0    1.1  1  Flavodoxin_2  Flavodoxin-like fold
    1.3e-06   28.3   0.0    1.7e-06   27.9   0.0    1.1  1  FMN_red       NADPH-dependent FMN reductase
    6.3e-05   23.2   0.1     0.0032   17.7   0.1    2.3  1  Flavodoxin_1  Flavodoxin
  ------ inclusion threshold ------
       0.04   14.2   0.0       0.24   11.6   0.0    1.9  2  Flavodoxin_5  Flavodoxin domain


Domain annotation for each model (and alignments):
>> Flavodoxin_2  Flavodoxin-like fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.7   0.0   2.6e-11   1.2e-07       2     147 ..       3     122 ..       2     146 .. 0.77

  Alignments for each domain:
  == domain 1  score: 31.7 bits;  conditional E-value: 2.6e-11
                   EEEEEE--TTGGCCHHHCHHHHHHHHHCCCTTTEEEEEEHHCC.T-----CCCCHCCHHHHTTCHHHHHHHHHHHHCSSEEEEEEE-BTTB--HHHH CS
  Flavodoxin_2   2 kiLiinahprpeksfssalaqafvealekagphevtvrdLyad.flpvlttrdlaaklayeekpadveseqiekllaadaivlqfPlwwfgvPailK 97 
                   ki i++ +  +  +   +la+a  +++e+ag  + ++  ++++ +  vlt+ +     a+++      +e  e ll+ da++++ P  + ++Pa+ K
    EEA21332.1   3 KIAIVFYSMYG--HV-AKLAEAEKKGVEAAG-GQADIYQIAETlPQEVLTKMY-----APPK-GDYPIAEP-ETLLEYDAVLFGIPTRYGNFPAQWK 88 
                   67777777776..45.89999999*******.99********99999999732.....3454.36778999.99*********************** PP

                   HHHHHHS-TTTSCEETTCSSCCCCTTTTSEEEEEEEESS-GGGSSTTSSS CS
  Flavodoxin_2  98 gwiDrvltagfafyteeggegrgggLkgkkalvivttGgpeesyqergle 147
                   ++ D+    g            +gg  gk+a v ++tG p+   q    e
    EEA21332.1  89 AFWDKT--GGI-W--------ASGGYWGKSAGVFISTGTPGG-GQ----E 122
                   *****5..555.3........247899************942.22....2 PP

>> FMN_red  NADPH-dependent FMN reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.9   0.0   3.8e-10   1.7e-06      17     144 ..      16     141 ..       3     147 .. 0.77

  Alignments for each domain:
  == domain 1  score: 27.9 bits;  conditional E-value: 3.8e-10
                 HHHHHHHHCCT-T.T-CEEEEETTTS.--..---HCHGHTCGGSHHHHHHHHHHHH-SCEEEEEEECTTCE-HHHHHHHHCHT-.SSCHCCTT-EEEEE CS
     FMN_red  17 rklaewaaealkeagaevelidladlilpcalcdkdlesegqtsddvaellekiaaadaliivtPeYngsysgllKnalDrlsrtrgkkelrgKpvalv 115
                  klae+ ++ +++ag ++++ ++a+  lp+ +++k    + +++d   +  e++ + da++++ P+  g+++++ K+++D ++ ++ +    gK ++++
  EEA21332.1  16 AKLAEAEKKGVEAAGGQADIYQIAET-LPQEVLTKMY--APPKGDYPIAEPETLLEYDAVLFGIPTRYGNFPAQWKAFWDKTGGIWASGGYWGKSAGVF 111
                 467777777888889999*******8.5542555555..345677777778********************************9888888888887666 PP

                 .EE-SSTTTTHHHHHHHHHHHHHTT-EEEE CS
     FMN_red 116 .avgggrrgglraeeqlrqvlaelgaivvp 144
                  ++g    g + ++ ++++ la++g   vp
  EEA21332.1 112 iSTGTPGGGQESTAIAAMSTLAHHGFSFVP 141
                 256544445556778889999887776666 PP

>> Flavodoxin_1  Flavodoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.1   7.2e-07    0.0032       1      62 [.       6      84 ..       6     155 .. 0.76

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 7.2e-07
                  EEEETSSSHHHHHHHHHHHHHHHTTTEEEEEEEEGTTSC..................GGGGGTHSEEEEEEEEETTTBEE CS
  Flavodoxin_1  1 ilYgSetGnteklAkqlaeelgehgfnadvvslsdydes..................lseieeealllvvtsTfgnGdpp 62
                  i+++S++G+  klA++ +++++++g +ad++++++   +                  ++ + e++ +l++++T + G +p
    EEA21332.1  6 IVFYSMYGHVAKLAEAEKKGVEAAGGQADIYQIAETLPQevltkmyappkgdypiaePETLLEYDAVLFGIPTRY-GNFP 84
                  89*************************999999887644444444455555555555555555555555555444.5555 PP

>> Flavodoxin_5  Flavodoxin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0      0.14   6.1e+02       2      34 ..       6      38 ..       5      47 .. 0.85
   2 ?   11.6   0.0   5.4e-05      0.24      37      68 ..      62      93 ..      36      97 .. 0.81

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.14
  Flavodoxin_5  2 ilYsSrdGqTkkiaeriaeelreegelvdvedv 34
                  i++ S +G+ +k ae+ ++ ++++g ++d+ ++
    EEA21332.1  6 IVFYSMYGHVAKLAEAEKKGVEAAGGQADIYQI 38
                  89999**********999999999988888886 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 5.4e-05
  Flavodoxin_5 37 esedlesydavvigasvyygkllpelakFvek 68
                  e e l +ydav++g + +yg+++ + ++F +k
    EEA21332.1 62 EPETLLEYDAVLFGIPTRYGNFPAQWKAFWDK 93
                  5568889******************9999776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (198 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       313  (0.0174578); expected 358.6 (0.02)
Passed bias filter:                      278  (0.0155056); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.46u 0.31s 00:00:00.77 Elapsed: 00:00:00.48
# Mc/sec: 1243.65
//
Query:       EEA21333.1  [L=175]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.2e-08   32.6   0.0    7.6e-08   32.3   0.0    1.1  1  Flavodoxin_2  Flavodoxin-like fold
    9.2e-07   28.7   0.0    1.2e-06   28.4   0.0    1.1  1  FMN_red       NADPH-dependent FMN reductase
    4.9e-05   23.6   0.2     0.0024   18.1   0.2    2.2  1  Flavodoxin_1  Flavodoxin
  ------ inclusion threshold ------
      0.029   14.6   0.0       0.19   12.0   0.0    1.9  2  Flavodoxin_5  Flavodoxin domain


Domain annotation for each model (and alignments):
>> Flavodoxin_2  Flavodoxin-like fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.3   0.0   1.7e-11   7.6e-08       2     148 ..       3     123 ..       2     147 .. 0.77

  Alignments for each domain:
  == domain 1  score: 32.3 bits;  conditional E-value: 1.7e-11
                   EEEEEE--TTGGCCHHHCHHHHHHHHHCCCTTTEEEEEEHHCC.T-----CCCCHCCHHHHTTCHHHHHHHHHHHHCSSEEEEEEE-BTTB--HHHH CS
  Flavodoxin_2   2 kiLiinahprpeksfssalaqafvealekagphevtvrdLyad.flpvlttrdlaaklayeekpadveseqiekllaadaivlqfPlwwfgvPailK 97 
                   ki i++ +  +  +   +la+a  +++e+ag  + ++  ++++ +  vlt+ +     a+++      +e  e ll+ da++++ P  + ++Pa+ K
    EEA21333.1   3 KIAIVFYSMYG--HV-AKLAEAEKKGVEAAG-GQADIYQIAETlPQEVLTKMY-----APPK-GDYPIAEP-ETLLEYDAVLFGIPTRYGNFPAQWK 88 
                   67777777776..45.89999999*******.99********99999999732.....3454.36778999.99*********************** PP

                   HHHHHHS-TTTSCEETTCSSCCCCTTTTSEEEEEEEESS-GGGSSTTSSS- CS
  Flavodoxin_2  98 gwiDrvltagfafyteeggegrgggLkgkkalvivttGgpeesyqergleg 148
                   ++ D+    g            +gg  gk+a v ++tG p+   q    e 
    EEA21333.1  89 AFWDKT--GGI-W--------ASGGYWGKSAGVFISTGTPGG-GQ----ES 123
                   *****5..555.3........247899*************42.22....22 PP

>> FMN_red  NADPH-dependent FMN reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.4   0.0   2.6e-10   1.2e-06      17     144 ..      16     141 ..       3     147 .. 0.77

  Alignments for each domain:
  == domain 1  score: 28.4 bits;  conditional E-value: 2.6e-10
                 HHHHHHHHCCT-T.T-CEEEEETTTS.--..---HCHGHTCGGSHHHHHHHHHHHH-SCEEEEEEECTTCE-HHHHHHHHCHT-.SSCHCCTT-EEEEE CS
     FMN_red  17 rklaewaaealkeagaevelidladlilpcalcdkdlesegqtsddvaellekiaaadaliivtPeYngsysgllKnalDrlsrtrgkkelrgKpvalv 115
                  klae+ ++ +++ag ++++ ++a+  lp+ +++k    + +++d   +  e++ + da++++ P+  g+++++ K+++D ++ ++ +    gK ++++
  EEA21333.1  16 AKLAEAEKKGVEAAGGQADIYQIAET-LPQEVLTKMY--APPKGDYPIAEPETLLEYDAVLFGIPTRYGNFPAQWKAFWDKTGGIWASGGYWGKSAGVF 111
                 467777777888889999*******8.5542555555..345677777778********************************9888888888887666 PP

                 .EE-SSTTTTHHHHHHHHHHHHHTT-EEEE CS
     FMN_red 116 .avgggrrgglraeeqlrqvlaelgaivvp 144
                  ++g    g + ++ ++++ la++g   vp
  EEA21333.1 112 iSTGTPGGGQESTAIAAMSTLAHHGFSFVP 141
                 256544445556778889999987777666 PP

>> Flavodoxin_1  Flavodoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.2   5.4e-07    0.0024       1      62 [.       6      84 ..       6     155 .. 0.76

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 5.4e-07
                  EEEETSSSHHHHHHHHHHHHHHHTTTEEEEEEEEGTTSC..................GGGGGTHSEEEEEEEEETTTBEE CS
  Flavodoxin_1  1 ilYgSetGnteklAkqlaeelgehgfnadvvslsdydes..................lseieeealllvvtsTfgnGdpp 62
                  i+++S++G+  klA++ +++++++g +ad++++++   +                  ++ + e++ +l++++T + G +p
    EEA21333.1  6 IVFYSMYGHVAKLAEAEKKGVEAAGGQADIYQIAETLPQevltkmyappkgdypiaePETLLEYDAVLFGIPTRY-GNFP 84
                  89*************************999999887644444444555555555555555555555555555444.5555 PP

>> Flavodoxin_5  Flavodoxin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0      0.11   4.9e+02       2      34 ..       6      38 ..       5      48 .. 0.86
   2 ?   12.0   0.0   4.1e-05      0.19      37      68 ..      62      93 ..      35      98 .. 0.80

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.11
  Flavodoxin_5  2 ilYsSrdGqTkkiaeriaeelreegelvdvedv 34
                  i++ S +G+ +k ae+ ++ ++++g ++d+ ++
    EEA21333.1  6 IVFYSMYGHVAKLAEAEKKGVEAAGGQADIYQI 38
                  89999**********999999999988888886 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 4.1e-05
  Flavodoxin_5 37 esedlesydavvigasvyygkllpelakFvek 68
                  e e l +ydav++g + +yg+++ + ++F +k
    EEA21333.1 62 EPETLLEYDAVLFGIPTRYGNFPAQWKAFWDK 93
                  5568899******************9999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (175 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       255  (0.0142228); expected 358.6 (0.02)
Passed bias filter:                      219  (0.0122148); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.41u 0.26s 00:00:00.67 Elapsed: 00:00:00.43
# Mc/sec: 1233.35
//
Query:       EEA21334.1  [L=292]
Description: mRNA cleavage and polyadenylation specificity factor complex subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.2e-15   56.1  37.3    2.4e-06   27.3   1.8    5.3  5  zf-CCCH    Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    6.2e-11   43.0  29.4    7.2e-05   23.4   1.1    5.3  5  Torus      Torus domain
    7.6e-10   38.5  36.2     0.0036   17.3   2.5    5.2  5  zf_CCCH_4  Zinc finger domain
    9.3e-05   22.1   2.3    9.3e-05   22.1   2.3    4.5  4  zf-CCCH_4  CCCH-type zinc finger


Domain annotation for each model (and alignments):
>> zf-CCCH  Zinc finger C-x8-C-x5-C-x3-H type (and similar)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.1   2.4e-06     0.011       3      22 ..      81      99 ..      79      99 .. 0.92
   2 !   13.7   2.6     1e-05     0.046       5      25 ..     128     147 ..     125     149 .. 0.94
   3 !   27.3   1.8   5.3e-10   2.4e-06       3      26 ..     154     177 ..     153     178 .. 0.93
   4 !    6.7   4.0    0.0015       6.9       5      21 ..     184     200 ..     182     206 .. 0.81
   5 !   12.7   1.9   2.1e-05     0.093       3      22 ..     207     225 ..     206     225 .. 0.91

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 2.4e-06
                CHCBCHHHHHS--TTGGG-S CS
     zf-CCCH  3 telCrffmrtGyCkyGdrCk 22
                ++ C+ f++ G+C+ G++C+
  EEA21334.1 81 VPVCKAFKE-GHCPLGPTCP 99
                689******.*********5 PP

  == domain 2  score: 13.7 bits;  conditional E-value: 1e-05
                 CBCHHHHHS--TTGGG-SSBS CS
     zf-CCCH   5 lCrffmrtGyCkyGdrCkFaH 25 
                  C++f++ G Ck G +C + H
  EEA21334.1 128 VCKHFLK-GLCKKGFKCEYLH 147
                 6******.************* PP

  == domain 3  score: 27.3 bits;  conditional E-value: 5.3e-10
                 CHCBCHHHHHS--TTGGG-SSBSC CS
     zf-CCCH   3 telCrffmrtGyCkyGdrCkFaHg 26 
                 +++C  f+r+GyC+ G+ C ++H+
  EEA21334.1 154 MPECASFSRSGYCPNGEDCLYHHV 177
                 689********************7 PP

  == domain 4  score: 6.7 bits;  conditional E-value: 0.0015
                 CBCHHHHHS--TTGGG- CS
     zf-CCCH   5 lCrffmrtGyCkyGdrC 21 
                 +C+ ++ +G+C+ G+ C
  EEA21334.1 184 PCCEHYDRGFCPLGPIC 200
                 68888888******977 PP

  == domain 5  score: 12.7 bits;  conditional E-value: 2.1e-05
                 CHCBCHHHHHS--TTGGG-S CS
     zf-CCCH   3 telCrffmrtGyCkyGdrCk 22 
                 ++lC++++  G+C+ G +C+
  EEA21334.1 207 QSLCPYYLA-GFCPDGRSCQ 225
                 579******.*********6 PP

>> Torus  Torus domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.4   0.3   0.00019      0.83      71      98 ..      82     109 ..      72     116 .. 0.84
   2 !   23.4   1.1   1.6e-08   7.2e-05      67      92 ..     123     148 ..     107     156 .. 0.82
   3 !   12.0   0.6   5.7e-05      0.26      72      91 ..     156     176 ..     148     182 .. 0.87
   4 !    8.7   0.9    0.0006       2.7      70      91 ..     183     204 ..     177     206 .. 0.85
   5 !    9.6   0.8   0.00031       1.4      65      89 ..     202     226 ..     201     250 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00019
                 -B-HHHHHT--SSGGG-SSB-S---SS- CS
       Torus  71 yfClfFarGlCakGkkCeylHrlPteed 98 
                  +C  F  G C+ G  C   H  P++  
  EEA21334.1  82 PVCKAFKEGHCPLGPTCPDRHPTPSRVT 109
                 69*******************9998765 PP

  == domain 2  score: 23.4 bits;  conditional E-value: 1.6e-08
                 STT--B-HHHHHT--SSGGG-SSB-S CS
       Torus  67 ekesyfClfFarGlCakGkkCeylHr 92 
                 +++s +C +F +GlC+kG kCeylH+
  EEA21334.1 123 THGSLVCKHFLKGLCKKGFKCEYLHE 148
                 45789********************7 PP

  == domain 3  score: 12.0 bits;  conditional E-value: 5.7e-05
                 B-HHHHH.T--SSGGG-SSB- CS
       Torus  72 fClfFar.GlCakGkkCeylH 91 
                  C  F+r G+C++G++C y H
  EEA21334.1 156 ECASFSRsGYCPNGEDCLYHH 176
                 599999889**********99 PP

  == domain 4  score: 8.7 bits;  conditional E-value: 0.0006
                 --B-HHHHHT--SSGGG-SSB- CS
       Torus  70 syfClfFarGlCakGkkCeylH 91 
                   +C ++ rG+C+ G  C+  H
  EEA21334.1 183 LPCCEHYDRGFCPLGPICAKQH 204
                 579***************9887 PP

  == domain 5  score: 9.6 bits;  conditional E-value: 0.00031
                 HHSTT--B-HHHHHT--SSGGG-SS CS
       Torus  65 dkekesyfClfFarGlCakGkkCey 89 
                 +++ ++ +C ++  G+C+ G++C++
  EEA21334.1 202 KQHVRQSLCPYYLAGFCPDGRSCQH 226
                 56678899***************96 PP

>> zf_CCCH_4  Zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.3   0.2   1.5e-05     0.066       1      16 [.      84      99 ..      84      99 .. 0.97
   2 !   15.9   5.2   2.2e-06    0.0099       1      19 []     129     147 ..     129     147 .. 0.99
   3 !   17.3   2.5     8e-07    0.0036       1      19 []     157     176 ..     157     176 .. 0.95
   4 ?    1.0   0.4      0.11   4.8e+02       1      12 [.     186     197 ..     186     200 .. 0.86
   5 !   10.4   1.7   0.00012      0.54       1      16 [.     210     225 ..     210     227 .. 0.94

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.5e-05
   zf_CCCH_4  1 CkfflqGtCkkGdkCr 16
                Ck f++G C+ G  C+
  EEA21334.1 84 CKAFKEGHCPLGPTCP 99
                ***************7 PP

  == domain 2  score: 15.9 bits;  conditional E-value: 2.2e-06
   zf_CCCH_4   1 CkfflqGtCkkGdkCrFaH 19 
                 Ck+fl+G CkkG kC ++H
  EEA21334.1 129 CKHFLKGLCKKGFKCEYLH 147
                 ******************* PP

  == domain 3  score: 17.3 bits;  conditional E-value: 8e-07
   zf_CCCH_4   1 Ckfflq.GtCkkGdkCrFaH 19 
                 C  f + G+C++G+ C + H
  EEA21334.1 157 CASFSRsGYCPNGEDCLYHH 176
                 889***************99 PP

  == domain 4  score: 1.0 bits;  conditional E-value: 0.11
   zf_CCCH_4   1 CkfflqGtCkkG 12 
                 C ++ +G C+ G
  EEA21334.1 186 CEHYDRGFCPLG 197
                 889999***988 PP

  == domain 5  score: 10.4 bits;  conditional E-value: 0.00012
   zf_CCCH_4   1 CkfflqGtCkkGdkCr 16 
                 C ++l+G C+ G +C+
  EEA21334.1 210 CPYYLAGFCPDGRSCQ 225
                 ************9997 PP

>> zf-CCCH_4  CCCH-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.1   1.1    0.0046        21       1      17 [.      82      98 ..      82     103 .. 0.88
   2 !   22.1   2.3   2.1e-08   9.3e-05       2      22 .]     128     148 ..     128     148 .. 0.97
   3 ?    0.4   1.0      0.13     6e+02       9      21 ..     164     176 ..     159     177 .. 0.88
   4 !    8.2   1.0   0.00049       2.2       2      17 ..     209     224 ..     208     225 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0046
   zf-CCCH_4  1 rlCpyfakGsCrfGdnC 17
                ++C+ f +G C  G+ C
  EEA21334.1 82 PVCKAFKEGHCPLGPTC 98
                69*********999877 PP

  == domain 2  score: 22.1 bits;  conditional E-value: 2.1e-08
   zf-CCCH_4   2 lCpyfakGsCrfGdnCrFsHd 22 
                 +C++f+kG C+ G +C ++H+
  EEA21334.1 128 VCKHFLKGLCKKGFKCEYLHE 148
                 7*******************6 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.13
   zf-CCCH_4   9 GsCrfGdnCrFsH 21 
                 G C  G+ C + H
  EEA21334.1 164 GYCPNGEDCLYHH 176
                 67*******9999 PP

  == domain 4  score: 8.2 bits;  conditional E-value: 0.00049
   zf-CCCH_4   2 lCpyfakGsCrfGdnC 17 
                 lCpy+++G C  G  C
  EEA21334.1 209 LCPYYLAGFCPDGRSC 224
                 8*********988888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (292 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       788  (0.0439511); expected 358.6 (0.02)
Passed bias filter:                      477  (0.0266049); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.51u 0.21s 00:00:00.72 Elapsed: 00:00:00.40
# Mc/sec: 2165.42
//
Query:       EEA21335.1  [L=391]
Description: class V chitinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      1e-69  235.7   0.1    1.2e-69  235.5   0.1    1.0  1  Glyco_hydro_18  Glycosyl hydrolases family 18


Domain annotation for each model (and alignments):
>> Glyco_hydro_18  Glycosyl hydrolases family 18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  235.5   0.1   6.5e-74   1.2e-69       3     312 .]      50     373 ..      48     373 .. 0.93

  Alignments for each domain:
  == domain 1  score: 235.5 bits;  conditional E-value: 6.5e-74
                     EEEEEGGGGGSS.G.C.SHTTTESEEEEEEEEEEETTTEEEESS.TTHH........HHHHHHHHHHHHTSTT-EEEEEEEETTT.TTHHHHHHT CS
                     xxxxxxxxxxxx.x.x.xxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxx........xxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxx RF
  Glyco_hydro_18   3 vgYysswesygn.n.y.lpsaklthiiyaFakidgengkvvvsd.wedl........gnfeqlkklkkkknpgvkvllsiGGwtd.ssgfslaas 84 
                     ++Yy +w+ y++     l++  ++h++yaFa +++  g+v +sd w+d         g+++++++lk +++p++kv+lsiGG ++ s++f ++a+
      EEA21335.1  50 AAYYPNWRIYKKqPpSsLRLGFVSHVFYAFAWVKE-GGTVYLSDeWADSqmpvdgteGCLRAFSQLK-QQYPQLKVILSIGGSGKgSENFVKVAT 142
                     68********773442588************9977.99*****************************.****************8799******* PP

                     SHHHHHHHHHHHHHHHHHCT-SEEEEEES-TTTSTCHHHHHHHHHHHHHHHHHHHHHHTSTTCEEEEEEESSHHHHHHHCHHHHHHHHTSEEEEE CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18  85 tdasrkkfadsvvsllrkygfDGiDidweypggnpedkenytallkelrealdkakategkkllLsaavpasasdlskgydlpkiakylDyvnvm 179
                     ++a+ ++fa s+ +l++++g+DGiD+dwe p++  +++e+++ ll++lr al        +++ ++ a+pa+++ l+++ +l  +++y+D + vm
      EEA21335.1 143 SPAAVANFAYSARALVDQFGLDGIDVDWEHPSD-SQQGEGFVYLLSQLRDALP------SPRYTVTCALPAGEWALKYI-NLGVAQQYVDLFMVM 229
                     *****************************9977.555*************999......589*************9777.*************** PP

                     TTTSSSTTSSBE--SS-SSB......T..CSSHHHHHHHHHHTT--GGGEEEEEESEEEEEEESSSSSS.....TSTTTEEEHHHHHHHHTEEEE CS
                     xxxxxxxxxxxxxxxxxxxx......x..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18 180 tYDfhgswdnvtghhaplyd......a..slnvdeavkeylkagvpakklvlGvpfygrawalvsgadn.....tkeegvlsykelkellkkaka 261
                      YDf+g+w ++tgh+++ly+      +   ++ ++av + l+++v+++k+ +G+p+ygr++ ++++ ++       ++gv++y +l++    ++ 
      EEA21335.1 230 CYDFSGPWLDRTGHQSQLYTpsnpysTaaAISCQSAVTYILSQSVQSNKILMGIPAYGRSFVGADNVNEsysgaDGDDGVFDYCDLPR----PGG 320
                     ********************987665156999999998888********************998874448888899********9998....799 PP

                     EEEEETTTTEEEEEETT..EEEEE-SHHHHHHHHHHHHHTTESEEEEETGGGS CS
                     xxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18 262 krkydskakapyvydge..efvsyDdpksikakadyvkakglgGvmiWsldqD 312
                     k++yd++ +a y + g+   fvsyD+p+++ +ka++v +++lgG++ W++ +D
      EEA21335.1 321 KEVYDDSLGAAYSVGGSdgGFVSYDTPQTVEQKAKFVTDSRLGGLFYWHITAD 373
                     9************998899*******************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (391 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       394  (0.0219756); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.24s 00:00:00.72 Elapsed: 00:00:00.40
# Mc/sec: 2945.15
//
Query:       EEA21336.1  [L=335]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    0.00066   19.0   0.2     0.0026   17.0   0.2    1.8  1  PNP_UDP_1  Phosphorylase superfamily


Domain annotation for each model (and alignments):
>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.2   1.5e-07    0.0026      74     203 ..      53     247 ..      29     272 .. 0.69

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 1.5e-07
                 EEEEEEEES....STTT-TT-EEEEEEEEESSSCCGCCTHHCC.......................................TCCCCTTSSEE--HHHH CS
   PNP_UDP_1  74 iriGtaGgl....npdlkvGDvvipddainfdgrsplygpkee.......................................gqyfpdsydapadpelr 129
                 +++G+ Gg+     pd+++GDvv+++    ++g  ++   k                                          +     + ++ d + +
  EEA21336.1  53 LMVGIGGGVpsatYPDIRLGDVVVSRPERTHSGVEQYDIGKATpsggfkrtgflnappkilrntvshltarhlrgegrfleyVAALSRLPTFTRDYAGL 151
                 57888888888778999*********9766666666555555577777778999999999999999999999999999999944444455555555555 PP

                 HHHHH.................CHHTTT.............TTEEEEEEEEESESS-CHHHHHHHHHHTC.-CEEESSHHHHHHHHHHTT--EEEEEEE CS
   PNP_UDP_1 130 allke.................aaealg.............ikvhrGvvatadgfyaeteaelrllrrlg.adaveMEtaavaqlArelgipfaairvv 197
                 ++l++                      +               +h+G+va+++++++  ++++    +lg + + eME+a +      ++ p+++i ++
  EEA21336.1 152 DILFAsnydhvgggsicdecdkT----HvlhrpgrraaqniSAIHYGTVASGNQVTRNAAERDCVSTDLGgVLCFEMEAAGL-----MNEFPCLVIWGI 241
                 55555555555555444444430....2444444555566699**************995555588888879999***9976.....478888888888 PP

                 EETTTB CS
   PNP_UDP_1 198 sdlaag 203
                 sd+ + 
  EEA21336.1 242 SDYSDS 247
                 884333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (335 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       446  (0.0248759); expected 358.6 (0.02)
Passed bias filter:                      408  (0.0227564); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.24s 00:00:00.71 Elapsed: 00:00:00.40
# Mc/sec: 2542.22
//
Query:       EEA21337.1  [L=344]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.5e-32  110.1   1.8    8.5e-32  110.1   1.8    2.3  3  DUF3712   Protein of unknown function (DUF3712)
  ------ inclusion threshold ------
      0.015   15.2   0.0      0.028   14.3   0.0    1.4  1  DUF2024   Domain of unknown function (DUF2024)
      0.055   14.0   0.3       0.15   12.6   0.3    1.8  1  LEA_2     Late embryogenesis abundant protein


Domain annotation for each model (and alignments):
>> DUF3712  Protein of unknown function (DUF3712)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.1      0.61   3.7e+03      84     105 ..      80     112 ..      67     119 .. 0.50
   2 !  110.1   1.8   1.4e-35   8.5e-32       2     125 .]     121     243 ..     120     243 .. 0.98
   3 ?   -1.5   0.0      0.49   2.9e+03      74      93 ..     260     280 ..     253     286 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.61
     DUF3712  84 fs........iedlqlllpdp...edginllat 105
                 fs        +++ q+l+++    ++ + ++at
  EEA21337.1  80 FSeptpntirVNQTQVLGNKAiyhPKIFEFNAT 112
                 333334444455555555555544445555555 PP

  == domain 2  score: 110.1 bits;  conditional E-value: 1.4e-35
     DUF3712   2 pfakvplpeikikgnsttglvdqtlditdvdaftkflealvlseefklsvkGkttlklgglkfkgvtldKtvtlkGlnslkgfsiedlqlllpdpedgi 100
                 p+a+v +p+ ++ ++++ ++ d  l+++d +a t+f +a+++seef+l+v G ++l+ g l++++vt++Kt+t+kG+ +lkgf+++++ + l++ +dg+
  EEA21337.1 121 PLAVVVVPQSQA-EDGAVIHFDTVLNLQDINAVTNFSRAVLSSEEFQLNVFGRPQLQEGPLPKTTVTFNKTITMKGMGGLKGFELQNMMISLTPAADGT 218
                 78999*******.7789999******************************************************************************* PP

     DUF3712 101 nllatvtlpNpsvvtielGnvtldl 125
                 n+++tv +pNpsvv++elGnvtl++
  EEA21337.1 219 NMNGTVFIPNPSVVSVELGNVTLNV 243
                 ***********************96 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 0.49
     DUF3712  74 tlkGlnslk.gfsiedlqlll 93 
                  ++G n l    si++ q+l+
  EEA21337.1 260 LMPGDNHLPlRSSINQTQVLS 280
                 488999999999999999985 PP

>> DUF2024  Domain of unknown function (DUF2024)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   4.7e-06     0.028      11      44 ..     131     164 ..     128     172 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 4.7e-06
                 --SSS--EEEEEEES---HHHHHHHHHHHHHHHT CS
     DUF2024  11 kkkdGkvlHFDvlvdekdeekaleyakeyLkskg 44 
                 +++dG v+HFD +++ +d + ++++++  L+s  
  EEA21337.1 131 QAEDGAVIHFDTVLNLQDINAVTNFSRAVLSSEE 164
                 579*************************999876 PP

>> LEA_2  Late embryogenesis abundant protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.3   2.5e-05      0.15       4      60 ..     226     280 ..     223     313 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 2.5e-05
                 EEESSSS-EEEEEEEEEEEESSSEEEEEEECE-EEESSSCEEEEEEEEEEEHHHHHH CS
       LEA_2   4 vrNPNsfgvrydgleldlsyngqrlasgtspqgfsqpargtttlevpvsvsaddlar 60 
                 + NP  ++v++ +++l +++n++ ++ +t  + +++ +++   l+++ s+++ ++++
  EEA21337.1 226 IPNPSVVSVELGNVTLNVYVNDTLIG-NTFINNVTLMPGDNH-LPLRSSINQTQVLS 280
                 67************************.999999998888776.66666666655555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (344 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       381  (0.0212505); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2418.50
//
Query:       EEA21338.1  [L=735]
Description: cell cycle inhibitor Nif1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-10   39.9  12.5      0.008   16.8   0.0    4.5  4  Sel1      Sel1 repeat


Domain annotation for each model (and alignments):
>> Sel1  Sel1 repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0      0.22   3.9e+03      28      38 .]     536     546 ..     522     546 .. 0.81
   2 !   11.4   0.2   2.3e-05      0.42       5      34 ..     553     578 ..     548     581 .. 0.87
   3 !   16.8   0.0   4.4e-07     0.008       4      34 ..     612     640 ..     606     643 .. 0.91
   4 !   15.9   2.1   8.5e-07     0.015       1      37 [.     645     679 ..     645     680 .. 0.91

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.22
        Sel1  28 ewyekAAeqGd 38 
                 ++++ AA+q++
  EEA21338.1 536 YHLRIAAKQNH 546
                 78999999987 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 2.3e-05
        Sel1   5 yrLGmfylylnGlgvpkDpekAiewyekAA 34 
                 y+L+  +   +G g  ++++++++w++kA 
  EEA21338.1 553 YALA--C--RHGWGMRANQKEGVQWLRKAV 578
                 7777..8..99999***************6 PP

  == domain 3  score: 16.8 bits;  conditional E-value: 4.4e-07
        Sel1   4 myrLGmfylylnGlgvpkDpekAiewyekAA 34 
                  y LG    +lnG g+++D+ +A++++e A 
  EEA21338.1 612 IYELG--VSHLNGWGIEQDKVLALRCFEIAS 640
                 699**..999******************996 PP

  == domain 4  score: 15.9 bits;  conditional E-value: 8.5e-07
        Sel1   1 aeAmyrLGmfylylnGlgvpkDpekAiewyekAAeqG 37 
                 a+A++  G   +y +G g +k+ +kA ++y++A ++G
  EEA21338.1 645 ADALAEAG--FCYAEGIGCKKNLKKAAHYYRLAEAKG 679
                 6799999*..999*******************97766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (735 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       554  (0.0308997); expected 358.6 (0.02)
Passed bias filter:                      261  (0.0145574); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.46
# Mc/sec: 4815.31
//
Query:       EEA21339.1  [L=292]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.3e-10   40.9  21.3    2.1e-10   40.3  21.3    1.3  1  Far-17a_AIG1  FAR-17a/AIG1-like protein
  ------ inclusion threshold ------
       0.12   11.9   0.0       0.27   10.8   0.0    1.6  1  Saf_2TM       SAVED-fused 2TM effector domain
        0.3   11.3   0.0        0.3   11.3   0.0    2.7  3  DUF4381       Domain of unknown function (DUF4381)
        2.7    7.6   0.0        2.7    7.6   0.0    3.4  3  DUF2101       Predicted membrane protein (DUF2101)


Domain annotation for each model (and alignments):
>> Far-17a_AIG1  FAR-17a/AIG1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.3  21.3   4.6e-14   2.1e-10       9     194 ..      43     234 ..      34     244 .. 0.73

  Alignments for each domain:
  == domain 1  score: 40.3 bits;  conditional E-value: 4.6e-14
  Far-17a_AIG1   9 tlcsyaalfypfhsekelaneaayGgkfkyLtfiglvlqalfftlallaD...........eltlsallklrdnllavlafPvevlvsvlFWgLyli 94 
                   ++  + +   +++++ +  n++a+G +f + t+++   +  +f+++++               +l ++ ++ + l+ ++++ + +lv+v++Wg    
    EEA21339.1  43 IFFCIIY--TYVYDS-THSNSVAIGQSFSFFTILNFWGMGFYFLVSAVHTllyaatgrsviLDRLPRVFRALHALFYTCMATLPFLVVVIYWGVLY- 135
                   2222222..223332.233445**************55555555555555555555666665699999*************************743. PP

  Far-17a_AIG1  95 DrelvypklldelipdWlnhsmHtvvlvailleifllkhkypsrlaalalsaafallYliwiervaqfngvwvYPvle.....alslegrvlffals 186
                          ++ ++ +  W n+s H ++ ++ lle++l+   +p  l  la+++ + llYl+    +++++g++ Y +l+     ++s ++    f+++
    EEA21339.1 136 -----SGSWFKDWFGAWSNISEHGLIGIYSLLEVCLTTT-PPHPLIHLAFLILILLLYLALAYLTHYTQGWYTYSFLDpgdhgQHSGKVAAYCFIIL 226
                   .....33455667***********************987.99***********************************73332244444444555555 PP

  Far-17a_AIG1 187 avvmally 194
                   a+++a+ +
    EEA21339.1 227 AAILAVFF 234
                   55544444 PP

>> Saf_2TM  SAVED-fused 2TM effector domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0     6e-05      0.27      65     105 ..     221     261 ..     166     286 .. 0.63

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 6e-05
     Saf_2TM  65 eivlaiilvigvllivvGavllilryvneakrqskkkvivI 105
                   + +++ +++v+++++G+++l +r  + + +++kk  + +
  EEA21339.1 221 YCFIILAAILAVFFVTWGLIWLRRRWTHGEIKRAKKDLVPV 261
                 2345556678899999*********9876666777776554 PP

>> DUF4381  Domain of unknown function (DUF4381)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.4       2.2     1e+04      19      36 ..      23      42 ..      13      52 .. 0.45
   2 ?    2.9   0.5     0.027   1.2e+02      16      44 ..     170     196 ..     166     207 .. 0.60
   3 ?   11.3   0.0   6.6e-05       0.3      23      57 ..     224     260 ..     217     284 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 2.2
     DUF4381 19 pGwwlllaalll..llllvl 36
                  w l  ++l l  ++++v+
  EEA21339.1 23 TSWLLSPVLLGLsrAVIAVY 42
                44444442222243333333 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.027
     DUF4381  16 PpapGwwlllaalllllllvlalwllrrr 44 
                 Pp p   l    l+l+lll+lal +l ++
  EEA21339.1 170 PPHPLIHLAF--LILILLLYLALAYLTHY 196
                 7777755555..45555555555555444 PP

  == domain 3  score: 11.3 bits;  conditional E-value: 6.6e-05
     DUF4381  23 lllaalllllllvlalwllrrrkrn..rreAlreLaa 57 
                 ++laa+l+++++ ++l +lrrr+++   + A + L  
  EEA21339.1 224 IILAAILAVFFVTWGLIWLRRRWTHgeIKRAKKDLVP 260
                 4455777788888888888888888787777777765 PP

>> DUF2101  Predicted membrane protein (DUF2101)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.7   9.2       3.7   1.7e+04      90     140 ..      80     135 ..      27     154 .. 0.69
   2 ?   -0.7   1.9      0.22     1e+03      59      77 ..     174     192 ..     153     206 .. 0.53
   3 ?    7.6   0.0   0.00061       2.7     118     162 ..     220     264 ..     213     269 .. 0.74

  Alignments for each domain:
  == domain 1  score: -4.7 bits;  conditional E-value: 3.7
     DUF2101  90 fylavsviailay...lgyvllrklslel..yyylvyllvivivvlvfryyfksry 140
                 fy+ vs + +l y   + +v+l +l+ ++   ++l y  ++++  lv+  y+ + y
  EEA21339.1  80 FYFLVSAVHTLLYaatGRSVILDRLPRVFraLHALFYTCMATLPFLVVVIYWGVLY 135
                 58888877776552225689999998654226788888777776666666655544 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.22
     DUF2101  59 lllaalleflllryilirn 77 
                 l+ +a+l ++ll+y+ + +
  EEA21339.1 174 LIHLAFLILILLLYLALAY 192
                 3444444444444433322 PP

  == domain 3  score: 7.6 bits;  conditional E-value: 0.00061
     DUF2101 118 ylvyllvivivvlvfryyfksrygrDytyGvveevkedlvkvfvh 162
                 ++ ++ ++ i  + f  +      r +t+G+++  k+dlv v+ +
  EEA21339.1 220 AYCFIILAAILAVFFVTWGLIWLRRRWTHGEIKRAKKDLVPVYGD 264
                 44455555555555666777778899****************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (292 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       922  (0.0514251); expected 358.6 (0.02)
Passed bias filter:                      388  (0.0216409); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 2033.00
//
Query:       EEA21340.1  [L=304]
Description: beta-hexosaminidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.7e-44  152.7   0.3    1.8e-43  149.3   0.3    1.9  1  Glyco_hydro_20  Glycosyl hydrolase family 20, catalytic domai


Domain annotation for each model (and alignments):
>> Glyco_hydro_20  Glycosyl hydrolase family 20, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  149.3   0.3   9.8e-48   1.8e-43       1     271 [.       6     250 ..       6     261 .. 0.86

  Alignments for each domain:
  == domain 1  score: 149.3 bits;  conditional E-value: 9.8e-48
  Glyco_hydro_20   1 fkyRGlmlDvaRhflsveeikrliDamaaaKlNvlHwHltDdqgwrleikkyPeLtekgakreskese..eelsgfYtkedireiveYAaergie 93 
                     +++RG+mlD++R+f++v+ i +l+ ++  + +Nv+HwH+ D+++++l     P  +e g +  ++ s+  +++  fY+ +di+++v+YA++ gi+
      EEA21340.1   6 YPHRGFMLDTGRKFFPVDAITKLLTLLHRYNFNVFHWHIYDAESFPLLW---PADQEDGDWTLTNASRkfSHTRHFYSPQDIQDVVAYAQRLGIR 97 
                     99*********************************************86...45566666666554443345556******************** PP

  Glyco_hydro_20  94 VipEidmPgHaraalkaypelvtkekaeqsveqsvqvevkesvlnptneetyeflekvldevaelfp.seyvHiGGDEvkkkqwkkspeiqalik 187
                     V pE+dmPgH+  +  +  +lv +           + e+++ +l++ n  t+++++++++ v   f   ++ H+GGDEv +  w++++       
      EEA21340.1  98 VYPETDMPGHSDIWGFWKRDLVVG---------TPDLEKPNAQLDIRNRMTLDYIRDLVSTVDRYFDsPDLHHFGGDEV-AMIWRTED------- 175
                     **********************99.........346788999************************9568899******.56787763....... PP

  Glyco_hydro_20 188 eeglksveelqsyfvkrvekilkekgkkligWdeilekgk.asklakknttvqsWrelekeaaeklakkgydvilspadalYlDf 271
                            ++l   f++ + +++ + +k++i+Wd+++++   + +  + + ++q+W++     ++k+++kg++vi+s++da+Y+  
      EEA21340.1 176 ------DRKLLTTFFDWL-RTVCSPNKSPIIWDDLITEPGnSLDDISTDWVIQTWHD---GVTQKVLEKGHRVIVSESDAFYIGN 250
                     ......355666776555.567788889*******99988688899999********...479*******************965 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (304 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       365  (0.0203581); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.32s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 1990.13
//
Query:       EEA21341.1  [L=246]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (246 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       756  (0.0421663); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.24s 00:00:00.67 Elapsed: 00:00:00.39
# Mc/sec: 1870.24
//
Query:       EEA21342.1  [L=455]
Description: ornithine aminotransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
     2e-101  339.6   0.0   2.5e-101  339.3   0.0    1.0  1  Aminotran_3    Aminotransferase class-III
  ------ inclusion threshold ------
      0.032   13.4   0.0      0.063   12.4   0.0    1.5  1  Aminotran_1_2  Aminotransferase class I and II


Domain annotation for each model (and alignments):
>> Aminotran_3  Aminotransferase class-III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  339.3   0.0  2.8e-105  2.5e-101      10     406 .]      58     446 ..      50     446 .. 0.93

  Alignments for each domain:
  == domain 1  score: 339.3 bits;  conditional E-value: 2.8e-105
                  C.EEEEEEEBTEEEETTS-EEEESSHHHHTTTT-BT-HHHHHHHHHHHTT-S---TTTCEEHHHHHHHHHHHHHCT-..SEEEEESSHHHHHHHHHHH CS
  Aminotran_3  10 l.lvitkaeGvyltdvdgkrylDlvssiavvnlGhahPkvvkavkeqaaklshvsfgaltnepalklaekllklapkgldkvflansGseAvetAlKl 106
                  + +++tk++G++l+d +gk+y+D+ +++++ n+Gh+hPk+v+a+ eq ++l + s + ++ ++++ +++k+ ++++   dkv + n G+eAv  A+K+
   EEA21342.1  58 HkVIMTKGQGAFLWDLEGKKYIDFNGGFSACNQGHCHPKIVQAMMEQCQQLAIPS-RSVHVAQYAMFCKKICEVTGF--DKVAMLNGGAEAVDMAIKF 152
                  33899**********************************************9998.999****************99..******************* PP

                  HHHHHHHTS..HCTT-EEEEETTT---SSHHHHHHSS--TTTTTTCTTB-TSEEEE-TTBGGGTB-HHHHHHHHHHHHHHHHCHTCCCEEEEEE-SCE CS
  Aminotran_3 107 arkyarekk..atektkiiafkgafHGrtlgalsvtgskkkyktlfgpflpevvrlkypdeevlkeneeeeaalleelealekkkkdevaAvivEpiq 202
                  ar++ +++k   + ++ +++ ++++HGr l  ls +++ + y++++gp +p+v    +   ++          ++e le+   k    +aA++vE +q
   EEA21342.1 153 ARAWGYKRKgiPEDQAIVLTAESNYHGRSLSLLSGSTD-ECYRKNCGPWMPNVGPYCAGNAIRF--------GVIEDLEEAFTKCGSRIAAFLVECVQ 241
                  ******99987788888899******************.**********999966555544443........3455677777999************* PP

                  TTTTSEB--CCHHHHHHHHHHHHT-EEEEE-TTTTTTTTSSSSGGGGCTS--SEEEE-GGGGTT.SS-EEEEEEHHHHTTS-TTSB--TTTT-HHHHH CS
  Aminotran_3 203 gegGvvvaspeflaklrelckkhdvllivDEvqtGfGrTGklfAlehagvspDlmtlaKaltgG.lplsavlataevmqalapgshgsTfgGnplaca 299
                  g +G  ++++e+l+++relc kh++l+i+DE+q G+GrTG lf +e+a+++pD+++l+K+++gG +p+savl+t++ m a++pg+ gsTf+Gnplaca
   EEA21342.1 242 GHAGCLAPTDEYLKAVRELCSKHNILFIADEIQAGLGRTGYLFSYESANIKPDMVILGKSISGGmYPISAVLGTTNAMGAIEPGQYGSTFSGNPLACA 339
                  ************************************************************************************************** PP

                  HHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHCTT-TTEEEEEEETTEEEEEEBCCCETTC...HHHHHHHHHCTEE-EEETTTEEEE---TT--HHH CS
  Aminotran_3 300 valavleiieeekllenaqelgaalkegLeelqkkyevikevRgkGlmiaielkeeaevke...keilkkakekGvlilsaGdnvirllppliitdee 394
                  vala+l++i +e+ll +a+ lg  ++++L e+++ y  + +v gkGl+ +i + e + + +   k++++  ++ G+l   aG + +r+ p+l+i ++ 
   EEA21342.1 340 VALAALNVILDEQLLSRARTLGTVFEKRLCEINSPY--FDTVTGKGLFRSIYIHETHPQGRvtgKRLVDLCLKRGLLANAAG-RRLRVCPSLVIDEAT 434
                  *********************************887..************96666555333556******************.99************* PP

                  HHHHHHHHHHHH CS
  Aminotran_3 395 idelleilkkal 406
                  + e+++il++al
   EEA21342.1 435 MLEGVDILEQAL 446
                  *********997 PP

>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0     7e-06     0.063     132     197 ..     218     281 ..     212     360 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 7e-06
                    HHHHHHHHTTHHCTTETEEEEEEESS-TTT--B--HHH.HHHHHHHHHHTTEEEEEEETTTTCBSSS CS
  Aminotran_1_2 132 lealeealkeapegnkktkvilvesphNPtGtvatlee.leklldlakkynlllfvDeaYagfvfgs 197
                    +e+leea +++ ++   +  +lve+++   G +a+ +e l+++ +l+ k+n+l + De+ ag+  + 
     EEA21342.1 218 IEDLEEAFTKCGSR---IAAFLVECVQGHAGCLAPTDEyLKAVRELCSKHNILFIADEIQAGLGRTG 281
                    57889988885433...46*********9999988877378899***************99888764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (455 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       368  (0.0205254); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.46
# Mc/sec: 2970.21
//
Query:       EEA21343.1  [L=853]
Description: hypothetical protein PMAA_051540 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.7e-29  101.4   0.0    6.9e-29  100.6   0.0    1.5  1  ApbA_C          Ketopantoate reductase PanE/ApbA C terminal
    1.2e-26   93.1   0.0    2.4e-26   92.2   0.0    1.5  1  ApbA            Ketopantoate reductase PanE/ApbA
    1.1e-23   83.7   0.1    1.6e-23   83.2   0.1    1.1  1  Fungal_trans_2  Fungal specific transcription factor domain
  ------ inclusion threshold ------
       0.21   10.9   3.2       0.37   10.1   1.3    2.3  3  ThiF            ThiF family


Domain annotation for each model (and alignments):
>> ApbA_C  Ketopantoate reductase PanE/ApbA C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.6   0.0   1.5e-32   6.9e-29       4     125 .]     207     328 ..     204     328 .. 0.91

  Alignments for each domain:
  == domain 1  score: 100.6 bits;  conditional E-value: 1.5e-32
      ApbA_C   4 larweKllinaainpltalldckngell.espelralvrallkEalavaeaegvelseerleeaveavlektaan.rsSMlqDveagrktEidyinGav 100
                  +rw+Kl++na++n+l+a++++++ +l+ +  ++++l+ +++ E+ ++a+a+gv+l ++  +e+v  + ++  a  r+SM+qD+e+g+ +E++ i+G+ 
  EEA21343.1 207 FMRWRKLVYNASFNSLCAITGMDTTKLRlSGSAVHELLLPVMLEIKNIARAAGVKLAPD--QEEVSLAGDAIDAYfRPSMQQDIEKGNYMEMEIIVGES 303
                 579*********************9999788899*********************9999..677777777766655*********************** PP

      ApbA_C 101 vklAeklgvetPvnellyellkale 125
                 v+ A++lgv++P++ ++y+llk l+
  EEA21343.1 304 VREAQRLGVPAPTLTFIYSLLKVLQ 328
                 *********************9875 PP

>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.2   0.0   5.4e-30   2.4e-26       1     151 [.      13     171 ..      13     172 .. 0.94

  Alignments for each domain:
  == domain 1  score: 92.2 bits;  conditional E-value: 5.4e-30
                 EEEES-SHHHHHHHHHHHHHTHC.EEEE-SCHHHHHHHHHCEEEEETT.CEEEEEECEEECCH....SCCCCS-ESEEEE-SSGGGHHH.HHHH.HGGG CS
        ApbA   1 iailGaGaiGsllaakLakagad.vtlilrsrrlealkknGlrltseg.geeilrppealsae....ekselepidlvivtvKayqtee.alee.ikpl 91 
                 i+++G+G+iG++ a++L + g   vt +lrs+ ++ +k++G+++ s++ g+   + p ++s+     e ++l+p+d+v+v++K+ ++    +++ i+p+
  EEA21343.1  13 ILVVGFGGIGTITAYNLEAGGLAtVTGVLRSN-YDMVKERGFKIWSCDhGDIPSWRPSTISKNvpnvEAESLTPFDYVVVCTKNIPDIPpTVADiIAPA 110
                 89***************9966555********.****************999999999999999*********************99987667779**9 PP

                 ECTC.EEEEEESSSSCHHHHHTTTSTTSEEEEEEEE-EEEEEETTEEEECS--EEEEEESS CS
        ApbA  92 ldpn.tvvlllqNGlgheeelrealpkprvlggvtthgatregpgevhhagkgeikigela 151
                 ++   t+++l+qNG++ e+++ +a+p +  ++g++  ++++++pg++ h++++ + ig+++
  EEA21343.1 111 ITAGhTAIVLVQNGINIEKPIIAAFPSNVAISGISRMSSAELAPGQIFHQDHDILIIGAFR 171
                 99877****************************************************9986 PP

>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.2   0.1   3.6e-27   1.6e-23      20     304 ..     461     765 ..     448     834 .. 0.86

  Alignments for each domain:
  == domain 1  score: 83.2 bits;  conditional E-value: 3.6e-27
  Fungal_trans_2  20 ssnpfrkvllplalsnkallhallalsafhlqskgpkdslereakrykslalkelqealaelsstls............rnekykdiLaaiLllc 102
                       np+rk+ + l ls + ll ++l+ +a h+ s++        a  ++++a++ ++ +la+ +s+ +              + ++++Laa+Ll  
      EEA21343.1 461 FHNPYRKLSV-LSLSFPVLLRSILSCAAEHMRSLDLCP--APLAVELHDQAIRAIRLELATWNSHRTtptsnsglpisvGMTADESLLAAVLLQP 552
                     5677777655.6778889*****************999..9**************************************99**********9988 PP

  Fungal_trans_2 103 sieissgd.vsdwrvhLeaatsliksrggskasssslsskarfllrifayldilssttlgrgpsfpseeyekllen........kkeesdsg... 185
                      +  +sg+ + + ++hLe   ++++ +g + +s + +s+ ++fll+ fa +d+  + + +r+p +p + ++    n        +      +   
      EEA21343.1 553 GAIAFSGSaPISVHTHLEIGFHMLTDLGYLRSSETLKSAIPKFLLQRFAIVDLGICVWHRRRPRIPVNTWLVGSANittkddaiH------Dtfd 641
                     887777776778******************999*******************************************876555552......1444 PP

  Fungal_trans_2 186 .....ldplmGcsnslilliseisrLarekrsarkdseleplsileeaseleqrllswkprssdlepdldeterasslskdltelfrlaaliyly 275
                          ++++ Gc+  ++  ++++++La+++  + +   ++++ i++ea +le+++++++ r+s+ ++++++ + + +++    ++f +aali l+
      EEA21343.1 642 diqpsFREMAGCPYNVYTFLNRVMHLAADMSCSPSP--QSQRVIYQEAITLETEIRTYELRISSPNQNRSPQSVPMDAV---RRAFTHAALILLL 731
                     44455888**********************999999..99**********************99999999999888888...9************ PP

  Fungal_trans_2 276 rlvlglppsspevqelvkkllellellp.....s 304
                     r+v   p+ssp+vq++v  ++ l++ +p     +
      EEA21343.1 732 RRVFLEPSSSPRVQNSVEIIFTLMDNIPvtqkrT 765
                     ***************************9765541 PP

>> ThiF  ThiF family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   1.3   8.4e-05      0.37      16      46 ..       8      38 ..       4      40 .. 0.89
   2 ?   -2.9   0.0      0.76   3.4e+03     102     121 ..      78      97 ..      69     109 .. 0.75
   3 ?   -2.4   0.0      0.55   2.5e+03     135     160 ..     377     403 ..     360     522 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 8.4e-05
                HHTSEEEEE--SHHHHHHHHHHHHHTTTEEE CS
                xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        ThiF 16 LrdskvllvGaGglGsellknLalsGvgklt 46
                +++s +l+vG Gg+G + + nL + G+  +t
  EEA21343.1  8 MAKSNILVVGFGGIGTITAYNLEAGGLATVT 38
                57899*****************999998765 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.76
                 S-HHHHTT-SEEEEESSSHH CS
                 xxxxxxxxxxxxxxxxxxxx RF
        ThiF 102 vleellesvDlVvdalDnie 121
                 v+ e l+ +D+Vv ++ ni+
  EEA21343.1  78 VEAESLTPFDYVVVCTKNIP 97 
                 45577888999999998875 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 0.55
                 -EEEEEEEETTEEEEEEE.EECCS-EC CS
                 xxxxxxxxxxxxxxxxxx.xxxxxxxx RF
        ThiF 135 iplieagtlgfegqvvvi.ipgktgcy 160
                  ++++a+t+++++++ v+ ++  ++c 
  EEA21343.1 377 NSVVQATTNATKHHLHVVgAKIADSCA 403
                 567888888888888888433334443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (853 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       489  (0.0272742); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.70u 0.32s 00:00:01.02 Elapsed: 00:00:00.54
# Mc/sec: 4776.68
//
Query:       EEA21344.1  [L=380]
Description: FMN-dependent dehydrogenase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   4.5e-103  344.9   0.0   5.8e-103  344.6   0.0    1.1  1  FMN_dh        FMN-dependent dehydrogenase
    0.00014   21.0   0.1    0.00042   19.4   0.0    1.7  2  IMPDH         IMP dehydrogenase / GMP reductase domain
    0.00019   20.7   0.0    0.00032   20.0   0.0    1.3  1  Glu_synthase  Conserved region in glutamate synthase


Domain annotation for each model (and alignments):
>> FMN_dh  FMN-dependent dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  344.6   0.0  9.7e-107  5.8e-103       3     346 ..      17     363 ..      15     365 .. 0.91

  Alignments for each domain:
  == domain 1  score: 344.6 bits;  conditional E-value: 9.7e-107
                 CCS-HHHHHHHH--STTSHHHHHHHHGGGGEEE---SSSS-SS-B--EEETTEEESSSEEE--BSTGGGTSTTHHHHHHHHHHHHTS-EEEETT-SS-H CS
      FMN_dh   3 krlpkkafayvaggagdevtlrenraaferirlrprvlrdvskvdlsttllGqklslPvliaPvglaklahpdgelalaraaakagipfvlstvastsl 101
                 ++l++k  ay+++g+ d +t+++n++a++r+r+ pr+lrdv+++d++tt++G+k+s+P++++P++++ lah+dgel + raaakagi ++ls++a++sl
  EEA21344.1  17 AKLDPKWSAYLNEGSMDLITVKANETAYDRYRIMPRILRDVTNIDTTTTIFGTKVSMPFGFSPAAMHCLAHEDGELGTSRAAAKAGIAMGLSHWATKSL 115
                 67888999******************************************************************************************* PP

                 HHHHHHHT......T-EEEEEE-CSSHHHHHHHHHHHHHCTESEEEEESSTSS---BHHHHHCT--BSTT-T.G.TTGGGSTSGSCCTTH..THHHHHH CS
      FMN_dh 102 eevaaaae......gplwfqlyvpkdrelteellkraeaagykalvltvDtpvlgkRerdlrngfslppklklrnllqelakpewaaealkkasaaaef 194
                 eev aa +      +p  +q +    +e + +l+++a +agykal++tvD+p+ g+R ++ rng+ lpp+lk  n++  l++ +  ++++         
  EEA21344.1 116 EEVIAAGKaipgqfNPYGIQTSGAARNEDISALVQKADKAGYKALLVTVDAPTIGRRLNEYRNGIDLPPGLKFPNISGDLDSFRAIKREA--------- 205
                 ***996332333335999999999**********************************************88666666666666555555......... PP

                 CCCHB-TC--HHH.HHHHHHHHS..SEEEEEEE-SHHHHHHHHHTT.ESEEEE--GGGTSSTT---HHHCHHHHHHHH...........SS-EEEESS- CS
      FMN_dh 195 vgkqldpsltwdd.ikwlreqtk..lplvvKGvltaedakraveaG.vdgivvSNHGGRqldgapatidvLpeiveav.........ggrievlvDgGi 280
                          t++d i wl + ++  +++++KG+ t+ed+ +a+ +  v+gi+vSNHGGRqldgapat+++Lp++v+a+         ++++ + +DgGi
  EEA21344.1 206 -------GTTFSDfIPWLSSVVPphMEIWLKGIYTPEDVIMAATYPrVQGIIVSNHGGRQLDGAPATLEALPDCVAAArsinasrtpENKLMIGIDGGI 297
                 .......5567766******998789****************99966***************************9999556655554459********* PP

                 -SHHHHHHHHHTT-SEEEESHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT-SBHHHHHCGGE CS
      FMN_dh 281 rrGsDvlkAlalGAdavllGRpflyglaagGeeGvervleilraelertmallGvksvaeldrsll 346
                 rrGsD++kAlalGAd+++ GR  ++gla++G++Gver+le+lr+ele +m+l G++svae++++ l
  EEA21344.1 298 RRGSDIFKALALGADFCFAGRIPIWGLAYNGQNGVERALELLREELEMCMRLSGCRSVAEIGPETL 363
                 **************************************************************9987 PP

>> IMPDH  IMP dehydrogenase / GMP reductase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.0   7.1e-08   0.00042     203     237 ..     284     318 ..     264     320 .. 0.75
   2 ?   -2.2   0.0      0.27   1.6e+03     298     325 ..     331     358 ..     325     363 .. 0.85

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 7.1e-08
                 HCTCT-EEEEES---SHHHHHHHHHTT-SEEEESC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       IMPDH 203 akkagvpviaDGGikysgdivkAlaaGadavmlGs 237
                 + +++  +  DGGi+   di kAla+Gad++  G+
  EEA21344.1 284 TPENKLMIGIDGGIRRGSDIFKALALGADFCFAGR 318
                 3344577888*********************9997 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.27
                 -HHHHHHHHHHHHHHHHHHHT-SSHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       IMPDH 298 svkevveqlvgglrsgmgylGaktieel 325
                  v++ +e l ++l  +m   G+++++e+
  EEA21344.1 331 GVERALELLREELEMCMRLSGCRSVAEI 358
                 578889999999************9987 PP

>> Glu_synthase  Conserved region in glutamate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   0.0   5.3e-08   0.00032     272     307 ..     286     321 ..     260     326 .. 0.84

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 5.3e-08
                   GGG-EEEEESS--SHHHHHHHHHHT-SEEE-SHHHH CS
  Glu_synthase 272 rdrvsliadGglktgadvvkalalGAdavgigtaal 307
                    +++ + +dGg++ g d++kalalGAd+   g++++
    EEA21344.1 286 ENKLMIGIDGGIRRGSDIFKALALGADFCFAGRIPI 321
                   68999**********************999888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (380 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       311  (0.0173462); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.47
# Mc/sec: 2433.37
//
Query:       EEA21345.1  [L=494]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.8e-33  116.0  35.0    3.5e-33  115.0  31.7    2.0  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.036   14.0   0.6        7.7    6.5   0.0    3.3  3  UL42      HCMV UL42
        1.3    9.5   4.2        1.1    9.7   0.7    2.5  2  DUF2583   Protein of unknown function (DUF2583)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.0  31.7   5.9e-37   3.5e-33       1     352 [.      65     435 ..      65     436 .. 0.86
   2 ?    2.3   0.1     0.011        65      88     120 ..     451     485 ..     438     488 .. 0.76

  Alignments for each domain:
  == domain 1  score: 115.0 bits;  conditional E-value: 5.9e-37
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa..sslwlllvlrvlqGl 97 
                 l+l+ ++++l+r+++g a p  ++++l ++ s + +l+t++++++++  +p   +  r+ + ++l   ++++++  ++++ +   ++  +lv r++ G+
  EEA21345.1  65 LWLMCVFAYLDRNNIGNAKPAGMQDALDLTNSRYAMLITIFFIAYVIVEVPSNLILMRVRPSWYLPGLMIAWGIV-VAGM-SqvKTYEGILVIRFFLGF 161
                 6888999****************************************************9999************.4444.33355558********** PP

       MFS_1  98 gagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg.......Wravfyilaivsllafvlfllllpeepperkrkspkeee. 188
                  +++++p++a l++ w++k e g+ ++++ ++  ++ ++  ll+g++++ l        Wr++f++ +i+++ ++++ ++ lp  p++++ ++p+e+  
  EEA21345.1 162 IEAGFMPGVAFLMSCWYKKHEIGKRFSIFFTALCAAGAISGLLSGAIIAGLDgahgmagWRWLFLLEGILTIGVAIVCIFILPNYPSTSRHFTPEERHl 260
                 ************************************************77778***********************88899999999999999988879 PP

       MFS_1 189 ............kgtgpaplvp..awkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrls.drlg 272
                             ++++  ++ p  a+ a   dp  + ++i+l+l   g++++++++p+   + +g++g  +++  + ++  v+a l+l++  ls dr++
  EEA21345.1 261 aairilhdrkvhESQQTLKMNPlqALVAASIDPKTY-FFIMLYLLDNGVATISYFIPTV-LSSMGYTG--ILAQWMTVPIWVVATLFLVGVSLSsDRTQ 355
                 999888888887444444444444577777777776.9999999999***********7.*******5..45555888888888888899999989988 PP

       MFS_1 273 rrrrlllallllllaalglallavtssavllllvlvliGf.glgfvfpsllalasdla..ppeeagtasglfntagslggalg 352
                   r++ ++++ +++a+ g++++ v    +++ ++++++ + g+ ++fp+++ ++s+ +  p e+++ a++l+n +g l+ + g
  EEA21345.1 356 D-RAWHITFGMAVAAVSGIIIVTVK--HAATRYAFICFYMaGVYCAFPLIMIWTSEAIafPDEKRAVAIALVNGIGDLAVLYG 435
                 5.88888888888888888888888..3344446666666699999**********9999****************9998776 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.011
       MFS_1  88 llvlrvlqGlga..galfpagaaliadwfpkeerg 120
                 + ++ +++G++a  +a++p++  ++ + ++k er+
  EEA21345.1 451 FTAMIAMCGACAviSAVMPVIFRYLPKATTKAERA 485
                 66777777777777888888888888888888886 PP

>> UL42  HCMV UL42
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0      0.21   1.2e+03      18      81 ..      14      75 ..       3      79 .. 0.57
   2 ?    3.4   0.1     0.012        71      75     103 ..     212     240 ..     203     250 .. 0.74
   3 ?    6.5   0.0    0.0013       7.7      80     104 ..     355     379 ..     346     385 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.21
        UL42 18 tyeqamglcpttvstppppppdcspppyrppyclvsspsprhtfdmdmmempatmhpttgayfd 81
                + +   g  ptt st p              y+  +    r  + +d++ +pa       ay+d
  EEA21345.1 14 SADTKAGSSPTTSSTEPDLSETFEDEV--SRYVPDTELEKRLVWKLDLVLLPALWLMCVFAYLD 75
                556667888888888876544333322..22444444455666666666666666666666655 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.012
        UL42  75 ttgayfdngwkwtfallvvailgiiflav 103
                   ga+   gw+w f l  +  +g+ ++++
  EEA21345.1 212 LDGAHGMAGWRWLFLLEGILTIGVAIVCI 240
                 56888899******987776666655443 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.0013
        UL42  80 fdngwkwtfallvvailgiiflavv 104
                  d  w+ tf + v a+ gii+++v 
  EEA21345.1 355 QDRAWHITFGMAVAAVSGIIIVTVK 379
                 5899****************99986 PP

>> DUF2583  Protein of unknown function (DUF2583)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.1      0.36   2.1e+03      35      57 ..     188     210 ..     172     221 .. 0.75
   2 ?    9.7   0.7   0.00019       1.1      22      75 ..     308     360 ..     297     364 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.36
     DUF2583  35 elelpellaeaallgifiGallW 57 
                 ++ ++ l a +a+ g++ Ga++ 
  EEA21345.1 188 SIFFTALCAAGAISGLLSGAIIA 210
                 55566677888999999999873 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.00019
     DUF2583  22 vaslaysvlnqlpelelpellaeaallgifiGallWlaGarvgGrekvadrywW 75 
                 va+++y + + l +++ + +la+   + i++ a l+l+G +++  ++ +dr w 
  EEA21345.1 308 VATISYFIPTVLSSMGYTGILAQWMTVPIWVVATLFLVGVSLSS-DRTQDRAWH 360
                 7899**************************************96.567888875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (494 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       821  (0.0457917); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.63u 0.31s 00:00:00.94 Elapsed: 00:00:00.48
# Mc/sec: 3069.00
//
Query:       EEA21346.1  [L=381]
Description: hypothetical protein PMAA_051570 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (381 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       489  (0.0272742); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.24s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2693.19
//
Query:       EEA21347.1  [L=428]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.3e-06   25.3   0.3    1.8e-05   24.2   0.3    1.7  1  CorA      CorA-like Mg2+ transporter protein


Domain annotation for each model (and alignments):
>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.2   0.3     1e-09   1.8e-05     171     257 ..     235     316 ..     114     340 .. 0.69

  Alignments for each domain:
  == domain 1  score: 24.2 bits;  conditional E-value: 1e-09
        CorA 171 revlkrllakaddkllddedkeylrdlldelerllemlealrerleslqdtyssllserlNrvmkvLTvltaiflPlTlitGiyGmN 257
                   +  ++++   +++  +e+   l+ ++d ++  l+ ++ +r+ l + ++ + ++ s +l +++k+LT ++++flPl l   i+  N
  EEA21347.1 235 AYA--AMVR---NDKAASEACAELELIRDAFQETLKRITLMRDGLFNASSVMEARASTQLGENVKLLTFISIFFLPLGLCMAIWSIN 316
                 333..3455...22233333345999****************************************************999999888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (428 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       838  (0.0467399); expected 358.6 (0.02)
Passed bias filter:                      630  (0.0351386); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.43
# Mc/sec: 2970.08
//
Query:       EEA21348.1  [L=804]
Description: hypothetical protein PMAA_051590 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-08   35.3   0.0    2.6e-08   34.4   0.0    1.5  1  AAA       ATPase family associated with various cellular acti
  ------ inclusion threshold ------
      0.015   15.7   0.2      0.054   13.9   0.0    2.0  2  AAA_16    AAA ATPase domain
      0.075   13.3   0.0       0.23   11.7   0.0    1.9  1  AAA_22    AAA domain
        0.1   12.2   0.0       0.36   10.4   0.0    1.9  1  Zot       Zonular occludens toxin (Zot)


Domain annotation for each model (and alignments):
>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.4   0.0   5.7e-12   2.6e-08       3     124 ..     451     563 ..     449     571 .. 0.79

  Alignments for each domain:
  == domain 1  score: 34.4 bits;  conditional E-value: 5.7e-12
                 EESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTSSS CS
         AAA   3 lyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksrsgseseeeervvnqLlteldgvkkkes 101
                 ++Gp G+GKTlla+ +a++   +++ + ++++  + ++   ++++el+   ++     +l+i E+d l ++rs   s  ++ +v++L+  l  ++    
  EEA21348.1 451 FHGPRGVGKTLLAEILAESHRLPLMLLRLTDFGLD-LSTFGENLKELMHLSSRWG--AVLVITEADGLLQARSLYGSMTRDAMVAALIDSLASYNG--- 543
                 89*****************9999999999998833.4444455555554433333..8**************777888888888888888887777... PP

                 TEEEEEEESSGGGSTHHHHSTTS CS
         AAA 102 kvivigatnrpdkldpallrgRf 124
                   i+i  t ++ +ld+ l  +++
  EEA21348.1 544 --IIIFFTSEIAQLDRSLK-DKL 563
                 ..9************9998.554 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   1.2e-05     0.054       5      47 ..     428     469 ..     427     522 .. 0.88
   2 ?   -2.2   0.0       1.1   4.8e+03     118     118 ..     633     633 ..     549     690 .. 0.58

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.2e-05
      AAA_16   5 ReeeleqLlsalervrsgrpelvllsGesGvGKsslvrellra 47 
                 R++  +qL++ ++ v ++ +    ++G++GvGK+ l++ l+++
  EEA21348.1 428 RQRYYQQLHDFVG-VTMPPGLFYHFHGPRGVGKTLLAEILAES 469
                 7788899999998.5555559999*************988876 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.1
      AAA_16 118 r 118
                 r
  EEA21348.1 633 R 633
                 1 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   5.1e-05      0.23      10      66 ..     451     499 ..     445     581 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 5.1e-05
      AAA_22  10 vtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsst.sskdllrellralgl 66 
                  +G+ G+GKT+l++ l+e++         r ++++  l+  + +++++ ++l + ++l
  EEA21348.1 451 FHGPRGVGKTLLAEILAESH---------RLPLMLLRLTDFGlDLSTFGENLKELMHL 499
                 69*****************9.........88888888888888777777777777665 PP

>> Zot  Zonular occludens toxin (Zot)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0     8e-05      0.36      80     153 ..     503     577 ..     480     604 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 8e-05
         Zot  80 kgallviDEcqeifpvrakegrkd.pevi.naftehRhlgwDivlltqdiskihkevralaekavklkrkaaigik 153
                  ga+lvi E+  +  +r+  g    ++++    + +  +++ i++ t +i++++  ++    + v ++++ a ++ 
  EEA21348.1 503 WGAVLVITEADGLLQARSLYGSMTrDAMVaALIDSLASYNGIIIFFTSEIAQLDRSLKDKLRL-VSFSNLSAEQMM 577
                 69************9999865432366664667899**********************76544.344444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (804 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       479  (0.0267165); expected 358.6 (0.02)
Passed bias filter:                      456  (0.0254337); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.68u 0.31s 00:00:00.99 Elapsed: 00:00:00.49
# Mc/sec: 4967.31
//
Query:       EEA21349.1  [L=513]
Description: histidine acid phosphatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      2e-24   86.7   0.0    3.4e-24   85.9   0.0    1.4  1  His_Phos_2  Histidine phosphatase superfamily (branch 2)


Domain annotation for each model (and alignments):
>> His_Phos_2  Histidine phosphatase superfamily (branch 2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.9   0.0   1.9e-28   3.4e-24       2     383 .]      72     442 ..      71     442 .. 0.85

  Alignments for each domain:
  == domain 1  score: 85.9 bits;  conditional E-value: 1.9e-28
                 EEEEEEEEE--SBB-SHHHHHHHHHHHHHHHH.........HHCHHTGCCGGGGT.........--SSSTTS.B-HHHHHHHHHHHHHHHHHCHTCCHT CS
  His_Phos_2   2 LksvvvviRHGdRtPkqkvkksvtspiflsllkkhkeKlkqlktalekkghfpgtyrkveveklqlilkwggelthaGrkqaeelGrqfrqrYplgLlr 100
                 +k++  v+RHG+R+P         +  ++ +  k+       + + ++ ++f g++   e++  +  l++ +  + +G+k+  +lG q+r rYp  ++ 
  EEA21349.1  72 VKQAAYVVRHGSRYPDRGAYNGWVAIQQRVQAAKA-----AGNLTAKGSLSFIGDW---EPVLTNPDLQIAQ-ESMTGYKEGHDLGYQLRARYP-DFYE 160
                 689999*************9888888888888655.....589999999*****99...5555556666666.8889*****************.**** PP

                 TSS--.TTEEEEEE..SSHHHHHHHHHHHHHHCHCCC---S-TTSTTGGG-TTTTCCCEEEHHHHCCCCHHCTTS....HHTCHHHCHHHTGGHCHHHH CS
  His_Phos_2 101 lhlty.kdlkiras..segRviaSAaafakGllglegeltdllskdkdllddsnaakdlldeakkklkelltega....eacpafewpikvakrvdelv 192
                 ++ ++      +as  +++Rv+++A+af++G l +e                  +   ++   +++++++ + ++    +acpaf      +    +  
  EEA21349.1 161 DGTKFyAWANQYASpiNKSRVVQTAKAFMQGYL-GEF----------------ADTYGTIVSINSTGSPNAIGNSlgpsDACPAFGM--GASGSSFNND 240
                 *988887777777744689**************.555................456666666677888888888888889*****99..7777888888 PP

                 CHCCCCCHHHHHHHCHHHCTTEEEE-HHHHHHHHHHHHHHHH.HHCT-TTGGGCTH..HCHHHHHHHHHHHHHHHC........TTTCCCCHHHHHHHH CS
  His_Phos_2 193 kylkedmdeniakrleqlcpgesnllakerwdklercfyekn.kfdiskicdlydemkydalhnrylkdleelyklakvipqEygigpeeklkiGllll 290
                  +++++ +++++kr+++l++g   ++a ++ ++  +c +e +    +s++c + ++  ++++ ++y++dl+++y+         g+g+ +      l  
  EEA21349.1 241 TNFAATWTPKVMKRVNSLVDGI-DFTAGDILQMPYLCGFESQiTGRLSPWCGVLTD--EELEYYEYTQDLHYYYGI--------GPGSTTPTSLLFLPF 328
                 999******************8.*******************8889**********..******************........888888777766555 PP

                 HHHHHHHCTSSSEECCS...CCCECS-SEEEEEE-HHHHHHHHHHCTTTTTBTTB.SSS......TTT..HCCCS-CT-EEEEEEEEE........... CS
  His_Phos_2 291 npllkkilndlqrtree...atperhvrlrlyfthdshiysllnaLglpeelagedslaa.....ldrlsaspelpymsqivfelyed........... 370
                 +++l+++l+    ++ +       + ++l++ f  d++i+ l + +g+++++a++ +l +     ++ ++as+++ + + ++fe+  +           
  EEA21349.1 329 LDSLMQLLQAGPGQKGKgidGASFDIPKLVMAFMNDNQIAELTAGMGIFDTDAQP-KLPIdkllkKRIYNASNFVSMRGTVIFEVLNCttkspshphgk 426
                 55555555555555545698788999************************99998.6666799*9**********************999999998888 PP

                 ....TCTTTEEEEEEEC CS
  His_Phos_2 371 ....ssekkfyvrllls 383
                     +s++  y+rl+l+
  EEA21349.1 427 kpttTSTD-DYIRLMLN 442
                 76533333.99999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (513 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       399  (0.0222544); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.44
# Mc/sec: 3475.07
//
Query:       EEA21350.1  [L=461]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.9e-97  325.6   0.0    3.6e-97  325.3   0.0    1.1  1  DUF1776       Fungal family of unknown function (DUF1776)
    0.00012   21.6   0.0     0.0052   16.3   0.0    2.1  2  adh_short     short chain dehydrogenase
     0.0046   16.5   0.0       0.32   10.5   0.0    2.2  2  adh_short_C2  Enoyl-(Acyl carrier protein) reductase


Domain annotation for each model (and alignments):
>> DUF1776  Fungal family of unknown function (DUF1776)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  325.3   0.0    6e-101   3.6e-97       1     295 [.     120     434 ..     120     435 .. 0.98

  Alignments for each domain:
  == domain 1  score: 325.3 bits;  conditional E-value: 6e-101
     DUF1776   1 arkdvvlvlGsptePltRsialDLerrGFiVfvtvesaeeeklvesedredIrplsvdd.....dpssieasleefaqslesphvalpgakphvlrLkg 94 
                 ark++v+++Gsp+eP+tR+ia DLerrGFiV+v+v+saeee++++ ++r+dIr+l +d       ps+i+ +l+ + + +++p+ + pg +ph+++L+g
  EEA21350.1 120 ARKEIVVIAGSPHEPMTRAIAEDLERRGFIVYVIVQSAEEEHTIQMQNRADIRALHLDLtitpsTPSEIHPALHVIYSLISQPQSPAPGIQPHTCQLSG 218
                 69********************************************************99***999********************************* PP

     DUF1776  95 vilvPslsyptgpietiplsswaselnerllspiltlqallplltsrakqkakiivvnpsissslnlpfhapEalvssalsalfevLkrelr....... 186
                 +i+ Psl+yptgpi ti+ sswa+++n+rllspil++q + pllt r+ +++ i++++psisssl++p++apE+ vs+als ++++L++elr       
  EEA21350.1 219 LIILPSLNYPTGPIPTITASSWADTINTRLLSPILITQLFTPLLTHRN-HSSSIVFLYPSISSSLSAPYAAPEVAVSRALSGFATSLRQELRllqfsng 316
                 **********************************************99.9***********************************************99 PP

     DUF1776 187 .phnidvtqikLGnldlangsqsnskiasvagsevlsWsesaralygpnyvsilskaisaksir...rgsslreLhnalfdllegss.........kkr 272
                  p n+dv+++kLGn+dl+     ++++ +vag+e+l+Ws+++r+lygp+y  + ++++ a++++   rgs++r+Lhna+fd++ + +          ++
  EEA21350.1 317 sPCNVDVVEMKLGNIDLG----PHYRMPQVAGTEILAWSHHHRSLYGPSYLASVEQRPAASTGPnaiRGSPARALHNAIFDSIAPPRksvlgrkkrREA 411
                 99***************8....6788899***************************99999999*******************9988899***999999 PP

     DUF1776 273 vvyvGkgarlyslvgkllpeglv 295
                 vvyvG+g+r y+++g+++p++lv
  EEA21350.1 412 VVYVGRGSRSYGIIGAWIPTSLV 434
                 *********************98 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    3.1   0.0    0.0095        57      12      59 ..     135     179 ..     123     192 .. 0.69
   2 !   16.3   0.0   8.6e-07    0.0052      90     168 ..     229     309 ..     212     333 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.0095
                 HHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTT CS
   adh_short  12 IGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvt 59 
                 + raia+ l ++G+ v+v+ +s+e+ +++  + ++  a++ a+++D+t
  EEA21350.1 135 MTRAIAEDLERRGFIVYVIVQSAEEEHTIQMQ-NR--ADIRALHLDLT 179
                 6689**************77776655444333.33..35666666665 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 8.6e-07
                 -SSGGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHH.HCTTEEEEEEE.EGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHG CS
   adh_short  90 sgpfselseeewervievNltgvflltravlpaml.kqssGrIvnvs.SvagkvpvagvaaYsAsKaavagltrslakela 168
                 +gp+  ++++ w ++i++ l +++l+t++++p +  +++s +Iv+   S+ +  + +  a+  A   a+ g++ sl++el+
  EEA21350.1 229 TGPIPTITASSWADTINTRLLSPILITQLFTPLLThRNHSSSIVFLYpSISSSLSAPYAAPEVAVSRALSGFATSLRQELR 309
                 678889999************************999999*****9853777777788888888888899999999999986 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    3.7   0.0    0.0065        39       7      51 ..     136     179 ..     132     185 .. 0.82
   2 !   10.5   0.0   5.4e-05      0.32      85     147 ..     230     296 ..     220     309 .. 0.76

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.0065
                   HHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSEEEE--TT CS
  adh_short_C2   7 GraiAkalaeeGaevvltdlneeakkrveelaeelgaevlecDVt 51 
                    raiA+ l ++G  v +  ++ e+ +++ +++++ + ++l++D t
    EEA21350.1 136 TRAIAEDLERRGFIVYVIVQSAEE-EHTIQMQNRADIRALHLDLT 179
                   589**********99999999998.66777777777778888876 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 5.4e-05
                   S-GGGH-HHHHHHHHHHHTHHHHHHHHHHHHHCTSC...CEEEEE.EEGGGTSBSTTTTHHHHHHHH CS
  adh_short_C2  85 gpfletsreefdraldvnlyslfllakaalplmkeg...gsivnl.ssvgaervvpnynaygaaKaa 147
                   gp+ +++ +++++++++ l s +l+++ + pl++++   +siv l  s++++ + p  +   a+  a
    EEA21350.1 230 GPIPTITASSWADTINTRLLSPILITQLFTPLLTHRnhsSSIVFLyPSISSSLSAPYAAPEVAVSRA 296
                   788899*************************666555779999986667776666666644444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (461 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       387  (0.0215851); expected 358.6 (0.02)
Passed bias filter:                      360  (0.0200792); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 3052.58
//
Query:       EEA21351.1  [L=149]
Description: calmodulin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.1e-40  133.3  11.9    1.2e-10   40.1   0.2    4.1  4  EF-hand_1        EF hand
    1.3e-33  115.3   5.7    6.3e-17   61.8   0.7    2.1  2  EF-hand_7        EF-hand domain pair
    3.7e-33  110.6   6.9    1.4e-09   37.1   0.1    4.1  4  EF-hand_6        EF-hand domain
      1e-29  102.2  10.5    7.6e-14   51.3   0.7    3.5  4  EF-hand_8        EF-hand domain pair
    1.5e-24   84.4  10.7    1.1e-06   27.9   0.0    4.3  4  EF-hand_5        EF hand
    3.7e-17   62.4   0.9    3.1e-09   37.0   0.1    2.1  2  EF-hand_9        EF-hand domain
      5e-11   42.5   0.7    0.00024   21.0   0.1    2.1  2  EF-hand_4        Cytoskeletal-regulatory complex EF hand
    9.8e-08   32.8   0.1     0.0011   19.7   0.0    2.1  2  EF-hand_11       EF-hand domain
    1.9e-06   28.2   0.3      0.012   16.0   0.0    2.1  2  SPARC_Ca_bdg     Secreted protein acidic and rich in cysteine
    2.7e-06   27.3   0.0     0.0027   17.7   0.0    2.3  2  UPF0154          Uncharacterised protein family (UPF0154)
    0.00052   18.7   0.0    0.00057   18.6   0.0    1.0  1  DUF5580          Family of unknown function (DUF5580)
     0.0013   19.3   0.2        3.1    8.4   0.0    2.8  2  FGAR-AT_linker   Formylglycinamide ribonucleotide amidotransf
     0.0022   17.8   2.7        1.1    9.2   0.1    4.0  4  VbhA             Antitoxin VbhA
     0.0025   18.5   0.7       0.44   11.3   0.1    2.4  2  DUF3349          Protein of unknown function (DUF3349)
     0.0027   17.7   1.1        5.9    6.8   0.0    3.4  4  Caleosin         Caleosin related protein
     0.0033   17.6   3.1        0.2   11.9   0.1    2.5  2  Dockerin_1       Dockerin type I domain
     0.0034   17.4   2.6       0.29   11.1   0.5    2.4  2  TerB             Tellurite resistance protein TerB
     0.0052   17.1   0.1          1    9.8   0.0    2.6  2  EF-hand_14       EF-hand domain
     0.0063   16.4   1.5      0.012   15.5   0.1    2.2  2  EF-hand_10       EF hand
     0.0095   16.3   1.7        2.4    8.5   0.1    2.3  2  RNA_pol_Rpb4     RNA polymerase Rpb4
  ------ inclusion threshold ------
      0.011   16.0   0.6       0.61   10.5   0.1    2.6  3  DUF1456          Protein of unknown function (DUF1456)
       0.02   14.8   9.0         11    6.0   0.3    5.0  4  Glycos_trans_3N  Glycosyl transferase family, helical bundle 
      0.046   13.9   0.1         13    6.0   0.0    2.2  2  MotA_activ       Transcription factor MotA, activation domain
      0.047   14.3   3.4       0.68   10.6   0.2    2.1  2  MgtE_N           MgtE intracellular N domain
       0.09   12.5   0.2        3.4    7.3   0.0    2.2  2  Peptidase_M24    Metallopeptidase family M24
      0.094   12.9   0.2        1.6    8.9   0.0    2.1  2  ApbA_C           Ketopantoate reductase PanE/ApbA C terminal
        0.1   12.7   1.3       0.24   11.6   0.5    1.9  2  DUF1296          Protein of unknown function (DUF1296)
       0.14   12.0   0.3        1.6    8.6   0.0    2.4  3  Phage_tail_S     Phage virion morphogenesis family
       0.21   11.7   1.9        3.6    7.7   0.0    3.5  4  DUF1707          Domain of unknown function (DUF1707)
       0.22   11.9   0.6        2.7    8.4   0.0    2.6  2  DED              Death effector domain
       0.23   11.3   0.1         24    4.8   0.0    3.1  4  GPHH             Voltage-dependent L-type calcium channel, IQ
        2.6    7.6   4.9        7.1    6.2   0.9    2.6  2  DUF533           Protein of unknown function (DUF533)


Domain annotation for each model (and alignments):
>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2   0.1     4e-12   2.2e-09       2      29 .]      13      40 ..      12      40 .. 0.95
   2 !   29.2   0.6   6.6e-10   3.7e-07       1      28 [.      48      75 ..      48      76 .. 0.94
   3 !   34.2   0.0   1.7e-11   9.6e-09       1      28 [.      85     112 ..      85     113 .. 0.96
   4 !   40.1   0.2   2.2e-13   1.2e-10       1      28 [.     121     148 ..     121     149 .] 0.96

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 4e-12
                HHHHHHHHTTTSSSEEEHHHHHHHHHHH CS
   EF-hand_1  2 lkeiFrefDkDgdGkIdfeEfkellkkl 29
                ++e+F++fDkDg+G I+ +E++e++++l
  EEA21351.1 13 FREAFAVFDKDGNGEITADELREVMRSL 40
                89***********************986 PP

  == domain 2  score: 29.2 bits;  conditional E-value: 6.6e-10
                HHHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1  1 elkeiFrefDkDgdGkIdfeEfkellkk 28
                el++i +e+D+D++G+Idf+Ef++++ +
  EEA21351.1 48 ELQDIVNELDVDRTGTIDFDEFLTMMVH 75
                799**********************975 PP

  == domain 3  score: 34.2 bits;  conditional E-value: 1.7e-11
                 HHHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1   1 elkeiFrefDkDgdGkIdfeEfkellkk 28 
                 el+ +F++fD+Dg+G+I+ +E+++++k+
  EEA21351.1  85 ELRAAFEVFDQDGSGTISADEMRRVMKS 112
                 799***********************98 PP

  == domain 4  score: 40.1 bits;  conditional E-value: 2.2e-13
                 HHHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1   1 elkeiFrefDkDgdGkIdfeEfkellkk 28 
                 e++e+++e+D+DgdG+Id++Ef++l+++
  EEA21351.1 121 EIEEMIKEADTDGDGTIDYQEFVHLMTH 148
                 79************************86 PP

>> EF-hand_7  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.4   0.4   5.5e-18   3.1e-15       3      70 ..      12      73 ..      10      74 .. 0.96
   2 !   61.8   0.7   1.1e-19   6.3e-17       2      70 ..      84     146 ..      83     147 .. 0.96

  Alignments for each domain:
  == domain 1  score: 56.4 bits;  conditional E-value: 5.5e-18
   EF-hand_7  3 klkeaFkelDtdgdgyldkeellrllrkifqgagegsklsdeelellfkefDtdkdGvisfdEFlkly 70
                + +eaF  +D+dg+g ++ +el++++r      + g ++++ el+++++e+D d+ G+i+fdEFl+++
  EEA21351.1 12 RFREAFAVFDKDGNGEITADELREVMR------SLGQNPTESELQDIVNELDVDRTGTIDFDEFLTMM 73
                5789***********************......999999**************************998 PP

  == domain 2  score: 61.8 bits;  conditional E-value: 1.1e-19
   EF-hand_7   2 eklkeaFkelDtdgdgyldkeellrllrkifqgagegsklsdeelellfkefDtdkdGvisfdEFlkly 70 
                  +l+ aF+ +D+dg+g ++ +e++r+++      + g++l+d e+e+++ke Dtd+dG+i+++EF++l+
  EEA21351.1  84 AELRAAFEVFDQDGSGTISADEMRRVMK------SIGEDLTDAEIEEMIKEADTDGDGTIDYQEFVHLM 146
                 57999***********************......9********************************99 PP

>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.1   0.1   2.5e-12   1.4e-09       1      31 []      12      41 ..      12      41 .. 0.96
   2 !   21.9   0.2   1.9e-07   0.00011       1      26 [.      48      73 ..      48      79 .. 0.91
   3 !   31.4   0.0   1.7e-10   9.7e-08       1      31 []      85     114 ..      85     114 .. 0.94
   4 !   22.0   0.1   1.8e-07    0.0001       2      27 ..     122     147 ..     121     149 .] 0.88

  Alignments for each domain:
  == domain 1  score: 37.1 bits;  conditional E-value: 2.5e-12
   EF-hand_6  1 elreaFklfDkdgdGkidaeElrkalrkalg 31
                ++reaF  fDkdg+G+i+a+Elr ++r +lg
  EEA21351.1 12 RFREAFAVFDKDGNGEITADELREVMR-SLG 41
                69*************************.887 PP

  == domain 2  score: 21.9 bits;  conditional E-value: 1.9e-07
   EF-hand_6  1 elreaFklfDkdgdGkidaeElrkal 26
                el+++ +++D+d++G+id++E+  ++
  EEA21351.1 48 ELQDIVNELDVDRTGTIDFDEFLTMM 73
                68999*****************9998 PP

  == domain 3  score: 31.4 bits;  conditional E-value: 1.7e-10
   EF-hand_6   1 elreaFklfDkdgdGkidaeElrkalrkalg 31 
                 elr+aF+ fD+dg+G+i+a+E+r++++ + g
  EEA21351.1  85 ELRAAFEVFDQDGSGTISADEMRRVMK-SIG 114
                 79************************9.765 PP

  == domain 4  score: 22.0 bits;  conditional E-value: 1.8e-07
   EF-hand_6   2 lreaFklfDkdgdGkidaeElrkalr 27 
                 ++e  k+ D+dgdG+id++E++++++
  EEA21351.1 122 IEEMIKEADTDGDGTIDYQEFVHLMT 147
                 66777899***************998 PP

>> EF-hand_8  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.0       0.4   2.3e+02      29      43 ..      14      28 ..      12      28 .. 0.81
   2 !   49.9   0.5   3.8e-16   2.1e-13       2      54 ..      25      75 ..      24      76 .. 0.97
   3 !   14.5   0.0   4.2e-05     0.024      25      47 ..      83     105 ..      77     105 .. 0.90
   4 !   51.3   0.7   1.4e-16   7.6e-14       2      54 ..      98     148 ..      98     149 .] 0.94

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.4
   EF-hand_8 29 dilfrefDtdgdGki 43
                ++ f  fD dg+G i
  EEA21351.1 14 REAFAVFDKDGNGEI 28
                567889******965 PP

  == domain 2  score: 49.9 bits;  conditional E-value: 3.8e-16
   EF-hand_8  2 kgkItreelrrilrilglkkglseeevdilfrefDtdgdGkisfeEFcvller 54
                +g+It +elr+ +r+lg++   +e+e++++++e+D d+ G+i+f+EF+ ++++
  EEA21351.1 25 NGEITADELREVMRSLGQN--PTESELQDIVNELDVDRTGTIDFDEFLTMMVH 75
                79*****************..******************************98 PP

  == domain 3  score: 14.5 bits;  conditional E-value: 4.2e-05
   EF-hand_8  25 eeevdilfrefDtdgdGkisfeE 47 
                 e e+++ f  fD+dg+G+is +E
  EEA21351.1  83 EAELRAAFEVFDQDGSGTISADE 105
                 6689****************887 PP

  == domain 4  score: 51.3 bits;  conditional E-value: 1.4e-16
   EF-hand_8   2 kgkItreelrrilrilglkkglseeevdilfrefDtdgdGkisfeEFcvller 54 
                 +g I+ +e+rr ++++g    l++ e++++++e+DtdgdG+i++ EF+ l+++
  EEA21351.1  98 SGTISADEMRRVMKSIGED--LTDAEIEEMIKEADTDGDGTIDYQEFVHLMTH 148
                 589**********888977..******************************98 PP

>> EF-hand_5  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.7   0.2   9.4e-09   5.3e-06       2      25 .]      14      37 ..      13      37 .. 0.92
   2 !   12.5   0.3   0.00014     0.079       6      25 .]      54      73 ..      48      74 .. 0.88
   3 !   27.9   0.0   1.9e-09   1.1e-06       1      25 []      86     110 ..      86     110 .. 0.94
   4 !   23.4   0.1   5.1e-08   2.9e-05       2      24 ..     123     145 ..     122     146 .. 0.86

  Alignments for each domain:
  == domain 1  score: 25.7 bits;  conditional E-value: 9.4e-09
                HHHHHHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5  2 kdtFqaiDlNgDGkIskeELktlv 25
                +++F  +D++g G I+++EL++++
  EEA21351.1 14 REAFAVFDKDGNGEITADELREVM 37
                678******************987 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 0.00014
                HHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5  6 qaiDlNgDGkIskeELktlv 25
                +++D+++ G+I+++E+ t++
  EEA21351.1 54 NELDVDRTGTIDFDEFLTMM 73
                689*************9976 PP

  == domain 3  score: 27.9 bits;  conditional E-value: 1.9e-09
                 HHHHHHHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5   1 lkdtFqaiDlNgDGkIskeELktlv 25 
                 l+++F+ +D +g+G+Is++E ++++
  EEA21351.1  86 LRAAFEVFDQDGSGTISADEMRRVM 110
                 6899******************987 PP

  == domain 4  score: 23.4 bits;  conditional E-value: 5.1e-08
                 HHHHHHH-SS-SSCE-HHHHHHH CS
   EF-hand_5   2 kdtFqaiDlNgDGkIskeELktl 24 
                 +++ +++D++gDG+I+ +E+  l
  EEA21351.1 123 EEMIKEADTDGDGTIDYQEFVHL 145
                 567899**************766 PP

>> EF-hand_9  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.0   0.1   5.6e-12   3.1e-09       3      63 ..      16      74 ..      14      76 .. 0.96
   2 !   24.5   0.1   4.5e-08   2.5e-05       3      63 ..      89     147 ..      87     149 .] 0.96

  Alignments for each domain:
  == domain 1  score: 37.0 bits;  conditional E-value: 5.6e-12
   EF-hand_9  3 vFevcDtqktGrVpvsrlidyLravtaqdpeeseLeelakelDPdgedasvdldtflrvmr 63
                 F v+D +  G+++  +l +++r  ++ +p+eseL++  +elD d   +++d+d fl++m 
  EEA21351.1 16 AFAVFDKDGNGEITADELREVMRSLGQ-NPTESELQDIVNELDVDRT-GTIDFDEFLTMMV 74
                59*************************.*****************99.***********95 PP

  == domain 2  score: 24.5 bits;  conditional E-value: 4.5e-08
   EF-hand_9   3 vFevcDtqktGrVpvsrlidyLravtaqdpeeseLeelakelDPdgedasvdldtflrvmr 63 
                  Fev+D +  G++   ++  +++  ++ d +++e+ee  ke+D dg  +++d   f + m 
  EEA21351.1  89 AFEVFDQDGSGTISADEMRRVMKSIGE-DLTDAEIEEMIKEADTDGD-GTIDYQEFVHLMT 147
                 7**************************.******************9.***********96 PP

>> EF-hand_4  Cytoskeletal-regulatory complex EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0   0.1   4.3e-07   0.00024       4      69 ..       5      73 ..       1      76 [. 0.84
   2 !   20.3   0.1   7.3e-07   0.00041       5      69 ..      82     146 ..      79     148 .. 0.87

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 4.3e-07
   EF-hand_4  4 leeleikkyweifsglk.pednkltgdkvapvlkn..skleedklekiwdladidedgkldfeefciam 69
                l e +i ++ e f   + + + ++t d++  v+++   + +e++l+ i +  d+d  g++df+ef  +m
  EEA21351.1  5 LTEEQIARFREAFAVFDkDGNGEITADELREVMRSlgQNPTESELQDIVNELDVDRTGTIDFDEFLTMM 73
                67788999999999885156889**********98324557899*********************9887 PP

  == domain 2  score: 20.3 bits;  conditional E-value: 7.3e-07
   EF-hand_4   5 eeleikkyweifsglkpednkltgdkvapvlkn..skleedklekiwdladidedgkldfeefciam 69 
                 ee e++  +e+f   ++ + +++ d++  v+k+    l++ ++e++ + ad d dg++d++ef+  m
  EEA21351.1  82 EEAELRAAFEVFD--QDGSGTISADEMRRVMKSigEDLTDAEIEEMIKEADTDGDGTIDYQEFVHLM 146
                 6778888888887..5678899*********984458**************************9877 PP

>> EF-hand_11  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.0   0.00054       0.3      25      85 ..      16      76 ..       5      85 .. 0.88
   2 !   19.7   0.0     2e-06    0.0011      22      81 ..      86     145 ..      73     149 .] 0.88

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00054
                HHHHH-TT-SSEE-HHHHHHHHHHHT----HHHHHHHHHTS-B-TTS-EEHHHHHHHHCS- CS
  EF-hand_11 25 efenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsklsie 85
                 f  fd      ++ +e+r +     q  t+ +++ + +el v+  g + +++fl+ +  +
  EEA21351.1 16 AFAVFDKDGNGEITADELREVMRSLGQNPTESELQDIVNELDVDRTGTIDFDEFLTMMVHK 76
                577888888889**********9999*****************************987655 PP

  == domain 2  score: 19.7 bits;  conditional E-value: 2e-06
                 HHHHHHHH-TT-SSEE-HHHHHHHHHHHT----HHHHHHHHHTS-B-TTS-EEHHHHHHH CS
  EF-hand_11  22 ivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsk 81 
                 +   fe fd   s t+s +e+r + +   + ltd +++ + +e   +  g + yq+f+  
  EEA21351.1  86 LRAAFEVFDQDGSGTISADEMRRVMKSIGEDLTDAEIEEMIKEADTDGDGTIDYQEFVHL 145
                 4568**********************999****************************865 PP

>> SPARC_Ca_bdg  Secreted protein acidic and rich in cysteine Ca binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.8   0.0   0.00085      0.48      59     111 ..      16      70 ..       2      72 .. 0.87
   2 !   16.0   0.0   2.1e-05     0.012      55     112 ..      85     144 ..      73     145 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00085
  SPARC_Ca_bdg  59 kFsklDtnsdkvlsksELaplrapl..vklehCikpflescDadkdkkislkEwc 111
                    F  +D++ ++ ++  EL+++  +l   ++e+  +  +++ D+d+ ++i+  E+ 
    EEA21351.1  16 AFAVFDKDGNGEITADELREVMRSLgqNPTESELQDIVNELDVDRTGTIDFDEFL 70 
                   69999*****************9994456899*********************96 PP

  == domain 2  score: 16.0 bits;  conditional E-value: 2.1e-05
  SPARC_Ca_bdg  55 pvawkFsklDtnsdkvlsksELaplrapl..vklehCikpflescDadkdkkislkEwce 112
                   +++  F+ +D++  +++s  E++ + +++  + ++  i+++++++D+d d++i+ +E+++
    EEA21351.1  85 ELRAAFEVFDQDGSGTISADEMRRVMKSIgeDLTDAEIEEMIKEADTDGDGTIDYQEFVH 144
                   56668999***************99998844567889********************975 PP

>> UPF0154  Uncharacterised protein family (UPF0154)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0   4.8e-06    0.0027      27      57 ..      25      55 ..      13      57 .. 0.90
   2 !    7.2   0.0    0.0089         5      30      57 ..     101     128 ..      99     130 .. 0.92

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 4.8e-06
     UPF0154 27 nPpinekmirammkqmGrkPSekqikqvmrs 57
                n  i+++ +r+ m++ G++P+e+ ++ ++++
  EEA21351.1 25 NGEITADELREVMRSLGQNPTESELQDIVNE 55
                7789**********************99986 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0089
     UPF0154  30 inekmirammkqmGrkPSekqikqvmrs 57 
                 i+++ +r  mk+ G  ++ + i++++++
  EEA21351.1 101 ISADEMRRVMKSIGEDLTDAEIEEMIKE 128
                 89999*******************9875 PP

>> DUF5580  Family of unknown function (DUF5580)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0     1e-06   0.00057     263     386 ..      18     147 ..       2     149 .] 0.79

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 1e-06
     DUF5580 263 asdelqqsktvvdsnpkktesssdek..stapqdsssesevnk....slleiLkmalktakgklnlenLnlsFrkeDrsfsGlLpppkvraiCgkhgly 355
                 a ++++ + +++ +++++   s  ++  ++  qd  +e +v++    ++ e L m +++ k+  +  +L+ +F   D+  sG+++  ++r + +  g  
  EEA21351.1  18 AVFDKDGNGEITADELREVMRSLGQNptESELQDIVNELDVDRtgtiDFDEFLTMMVHKGKATDEEAELRAAFEVFDQDGSGTISADEMRRVMKSIGED 116
                 555555666666666655544433332455666776777777665557889*********999999********************************* PP

     DUF5580 356 ltlslletllnhqdlgyqdeikWqnfvelLs 386
                 lt + +e +++  d    + i +q+fv+l++
  EEA21351.1 117 LTDAEIEEMIKEADTDGDGTIDYQEFVHLMT 147
                 ****************************986 PP

>> FGAR-AT_linker  Formylglycinamide ribonucleotide amidotransferase linker domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.1   0.0    0.0071         4      15      37 ..      31      50 ..       3      52 .. 0.71
   2 !    8.4   0.0    0.0055       3.1      12      37 ..     101     123 ..      93     126 .. 0.90

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0071
  FGAR-AT_linker 15 eEidylqeafeklgrnPtdvEle 37
                    +    l+e++++lg+nPt  El+
      EEA21351.1 31 D---ELREVMRSLGQNPTESELQ 50
                    3...34444477*********96 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0055
  FGAR-AT_linker  12 LsdeEidylqeafeklgrnPtdvEle 37 
                     +s +E++++ +    +g++ td+E+e
      EEA21351.1 101 ISADEMRRVMKS---IGEDLTDAEIE 123
                     689*********...9********97 PP

>> VbhA  Antitoxin VbhA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.2   0.1    0.0019       1.1      32      45 ..      25      38 ..      25      39 .. 0.86
   2 ?    0.3   0.0       1.2   6.6e+02      33      40 ..      62      69 ..      60      71 .. 0.87
   3 ?    5.1   0.0     0.037        21      33      44 ..      99     110 ..      98     112 .. 0.86
   4 ?   -2.3   0.0       7.5   4.2e+03      32      41 ..     134     143 ..     134     146 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0019
        VbhA 32 rGeIdadElvrrvr 45
                +GeI+adEl++ +r
  EEA21351.1 25 NGEITADELREVMR 38
                5*********9776 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 1.2
        VbhA 33 GeIdadEl 40
                G+Id dE 
  EEA21351.1 62 GTIDFDEF 69
                9*****97 PP

  == domain 3  score: 5.1 bits;  conditional E-value: 0.037
        VbhA  33 GeIdadElvrrv 44 
                 G+I+adE++r +
  EEA21351.1  99 GTISADEMRRVM 110
                 9********966 PP

  == domain 4  score: -2.3 bits;  conditional E-value: 7.5
        VbhA  32 rGeIdadElv 41 
                 +G+Id  E v
  EEA21351.1 134 DGTIDYQEFV 143
                 6999999987 PP

>> DUF3349  Protein of unknown function (DUF3349)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.3   0.1   0.00079      0.44      31      87 ..       2      57 ..       1      65 [. 0.88
   2 ?    5.6   0.1     0.047        27      25      62 ..     108     142 ..      98     149 .] 0.72

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00079
                CTT--HHHHHHHHHHHHHH--.SSS.BSHHHCHHHHHHHCTS---HHHHHHHHHHHH CS
     DUF3349 31 rrrLsdeevkevaeelvaeaaeadeavdeedieelitkvteeepseedvarVaarLa 87
                +++L++e++++  e+++  +++ ++++++++++e++++   ++p+e++++ + ++L 
  EEA21351.1  2 AESLTEEQIARFREAFAVFDKDGNGEITADELREVMRS-LGQNPTESELQDIVNELD 57
                678**********9999988899**********98865.6789*******9998885 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.047
                 HHHHHHCTT--HHHHHHHHHHHHHH--.SSS.BSHHHC CS
     DUF3349  25 pLlalLrrrLsdeevkevaeelvaeaaeadeavdeedi 62 
                 +++  + ++L+d+e++e+++e  +++   d+++d ++ 
  EEA21351.1 108 RVMKSIGEDLTDAEIEEMIKEADTDG---DGTIDYQEF 142
                 56666778899999999999988887...566666655 PP

>> Caleosin  Caleosin related protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.0      0.01       5.9      94     121 ..      12      39 ..       8      45 .. 0.67
   2 ?    5.3   0.1      0.03        17      93     158 ..      47     107 ..      41     112 .. 0.66
   3 ?    4.3   0.1      0.06        33       5      36 ..      85     116 ..      81     132 .. 0.70
   4 ?    1.0   0.0      0.62   3.5e+02      93     121 ..     120     148 ..     116     149 .] 0.77

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.01
    Caleosin  94 kfeeifskyakekkdaltlkevlellkg 121
                 +f e f+ ++k+ ++++t++e+ e++++
  EEA21351.1  12 RFREAFAVFDKDGNGEITADELREVMRS 39 
                 6667777777777777777777766654 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.03
    Caleosin  93 qkfeeifskyakekkdaltlkevlellkgqrealDlfgwlaallewlalylllkdkdgllkkedvr 158
                 +++++i ++ + ++++++ ++e+l+++ ++ +a+D  + l a +e        +d +g+++ +++r
  EEA21351.1  47 SELQDIVNELDVDRTGTIDFDEFLTMMVHKGKATDEEAELRAAFEVF-----DQDGSGTISADEMR 107
                 56777888888888888888888888888888888776666666632.....23444455555555 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.06
    Caleosin   5 vLqqHvaFfDrdkdGiiypldtyrgfralgfn 36 
                  L+  ++ fD+d  G+i   ++ r ++++g +
  EEA21351.1  85 ELRAAFEVFDQDGSGTISADEMRRVMKSIGED 116
                 45555666888888888777777777777655 PP

  == domain 4  score: 1.0 bits;  conditional E-value: 0.62
    Caleosin  93 qkfeeifskyakekkdaltlkevlellkg 121
                 ++ ee+ ++ +++ ++++ ++e+++l+++
  EEA21351.1 120 AEIEEMIKEADTDGDGTIDYQEFVHLMTH 148
                 67788888888888888888888888765 PP

>> Dockerin_1  Dockerin type I domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.5     0.028        16       2      46 ..      20      65 ..      19      74 .. 0.77
   2 !   11.9   0.1   0.00036       0.2       2      50 ..      93     142 ..      92     148 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.028
                TETTSSSC-SHHHHHHHHHHCT.SSEBTTSCCCHGGGSTT-SSCES CS
  Dockerin_1  2 gDVNgDgkVnalDalliinyln.qregqssssngkaaDvNgDGrvn 46
                +D +g+g+++a  +  + + l  + ++++ +   + +Dv++ G+++
  EEA21351.1 20 FDKDGNGEITADELREVMRSLGqNPTESELQDIVNELDVDRTGTID 65
                5889999999999999999999555555566677889999999887 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 0.00036
                 TETTSSSC-SHHHHHHHHHHCT.SSEBTTSCCCHGGGSTT-SSCESHHHH CS
  Dockerin_1   2 gDVNgDgkVnalDalliinyln.qregqssssngkaaDvNgDGrvnalDa 50 
                 +D +g+g+++a  + ++ + +  + ++ + +++ k aD +gDG+++   +
  EEA21351.1  93 FDQDGSGTISADEMRRVMKSIGeDLTDAEIEEMIKEADTDGDGTIDYQEF 142
                 5889999999999999999999888999999**************97665 PP

>> TerB  Tellurite resistance protein TerB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   0.3     0.016       8.8      42     110 ..      26      92 ..      23      98 .. 0.82
   2 !   11.1   0.5   0.00052      0.29      42      91 ..      99     146 ..      80     149 .] 0.90

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.016
        TerB  42 gqvsesErqafrellksrfglspeeakallelfeeaeeeavdleqftralkrklspeqrraliealwei 110
                 g+++++E + +++ l ++    + e+++++ + +  ++ ++d+++f   +  k +  + +a ++a +e+
  EEA21351.1  26 GEITADELREVMRSLGQNPT--ESELQDIVNELDVDRTGTIDFDEFLTMMVHKGKATDEEAELRAAFEV 92 
                 78999999999999966666..999*********************99887777766666667777766 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00052
        TerB  42 gqvsesErqafrellksrfglspeeakallelfeeaeeeavdleqftral 91 
                 g++s++E++++++ +    +l+++e+++ +++++   + ++d+++f+  +
  EEA21351.1  99 GTISADEMRRVMKSI--GEDLTDAEIEEMIKEADTDGDGTIDYQEFVHLM 146
                 789************..88999************************9765 PP

>> EF-hand_14  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0      0.07        39       6      46 ..      17      57 ..      15      76 .. 0.88
   2 !    9.8   0.0    0.0018         1       6      45 ..      90     129 ..      87     145 .. 0.91

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.07
  EF-hand_14  6 fdlfkdeetdklsvakllkaLaetGirkdDpRLkellkklk 46
                f +f++++++++   +l +++++ G + +   L++++++l 
  EEA21351.1 17 FAVFDKDGNGEITADELREVMRSLGQNPTESELQDIVNELD 57
                8899999******************9999999998888775 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.0018
  EF-hand_14   6 fdlfkdeetdklsvakllkaLaetGirkdDpRLkellkkl 45 
                 f++f++++++++s  ++ +++++ G   +D  ++e++k+ 
  EEA21351.1  90 FEVFDQDGSGTISADEMRRVMKSIGEDLTDAEIEEMIKEA 129
                 9***********************************9975 PP

>> EF-hand_10  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0       3.7   2.1e+03      30      49 ..      20      39 ..       4      40 .. 0.67
   2 !   15.5   0.1   2.1e-05     0.012       2      46 ..     101     145 ..     100     148 .. 0.94

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 3.7
  EF-hand_10 30 cDkSksgrLegeEieeFykl 49
                 Dk  +g +   E+ e +++
  EEA21351.1 20 FDKDGNGEITADELREVMRS 39
                46667777777776666555 PP

  == domain 2  score: 15.5 bits;  conditional E-value: 2.1e-05
  EF-hand_10   2 msfkEvkrlLreiNievddeYAekLFkkcDkSksgrLegeEieeF 46 
                 +s +E++r ++ i  ++ d   e++ k++D+  +g+++ +E+++ 
  EEA21351.1 101 ISADEMRRVMKSIGEDLTDAEIEEMIKEADTDGDGTIDYQEFVHL 145
                 5889**************************************986 PP

>> RNA_pol_Rpb4  RNA polymerase Rpb4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.5   0.1    0.0042       2.4      92     119 ..      29      56 ..      28      58 .. 0.94
   2 ?    6.8   0.2     0.014       7.9      92     118 ..     102     128 ..      99     131 .. 0.92

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.0042
                   SHHHHHHHSTTGTTTSTSHHHHHHHHHH CS
  RNA_pol_Rpb4  92 savelktlieeleerfedeqleeiLdel 119
                   +a+el+ ++ +l +  ++++l++i++el
    EEA21351.1  29 TADELREVMRSLGQNPTESELQDIVNEL 56 
                   79************************98 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.014
                   SHHHHHHHSTTGTTTSTSHHHHHHHHH CS
  RNA_pol_Rpb4  92 savelktlieeleerfedeqleeiLde 118
                   sa+e + ++ ++ e ++d ++ee+++e
    EEA21351.1 102 SADEMRRVMKSIGEDLTDAEIEEMIKE 128
                   899**********************97 PP

>> DUF1456  Protein of unknown function (DUF1456)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0      0.19   1.1e+02      14      39 ..      28      53 ..      11      70 .. 0.70
   2 ?   -1.9   0.0         8   4.5e+03      23      39 ..      74      90 ..      63      97 .. 0.62
   3 ?   10.5   0.1    0.0011      0.61      14      54 ..     101     141 ..     100     147 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.19
     DUF1456 14 lkdedmveifklggvevtkeelsalL 39
                ++ +++ e++++ g + t++el+++ 
  EEA21351.1 28 ITADELREVMRSLGQNPTESELQDIV 53
                45555566666666666666666554 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 8
     DUF1456 23 fklggvevtkeelsalL 39
                + +g  + +++el+a +
  EEA21351.1 74 VHKGKATDEEAELRAAF 90
                45555555666666655 PP

  == domain 3  score: 10.5 bits;  conditional E-value: 0.0011
     DUF1456  14 lkdedmveifklggvevtkeelsalLkkedeegyeeckdqv 54 
                 ++ ++m +++k+ g  +t +e+++++k+ d +g   ++ q 
  EEA21351.1 101 ISADEMRRVMKSIGEDLTDAEIEEMIKEADTDGDGTIDYQE 141
                 7899***********************99888766665555 PP

>> Glycos_trans_3N  Glycosyl transferase family, helical bundle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.1      0.53     3e+02      12      24 ..       4      16 ..       1      19 [. 0.59
   2 ?    5.4   0.4      0.03        17       9      25 ..      23      40 ..      21      91 .. 0.83
   3 ?    5.4   0.1     0.029        16       9      34 ..      96     121 ..      95     122 .. 0.79
   4 ?    6.0   0.3     0.019        11      10      24 ..     114     128 ..     111     140 .. 0.85

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.53
                     ---HHHHHHHHHH CS
  Glycos_trans_3N 12 eLtaeeirfaihg 24
                     +Lt+e+i+ + ++
       EEA21351.1  4 SLTEEQIARFREA 16
                     5666666665444 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.03
                     TT..---HHHHHHHHHHH CS
  Glycos_trans_3N  9 dg.eeLtaeeirfaihgi 25
                     dg +e ta+e+r++++ +
       EEA21351.1 23 DGnGEITADELREVMRSL 40
                     676799999999999865 PP

  == domain 3  score: 5.4 bits;  conditional E-value: 0.029
                      TT..---HHHHHHHHHHHHTTSS-HHH CS
  Glycos_trans_3N   9 dg.eeLtaeeirfaihgilkgevtdaq 34 
                      dg ++ +a+e+r +++ i + ++tda+
       EEA21351.1  96 DGsGTISADEMRRVMKSIGE-DLTDAE 121
                      67689***********9977.556665 PP

  == domain 4  score: 6.0 bits;  conditional E-value: 0.019
                      T.---HHHHHHHHHH CS
  Glycos_trans_3N  10 geeLtaeeirfaihg 24 
                      ge+Lt++ei+++i++
       EEA21351.1 114 GEDLTDAEIEEMIKE 128
                      79**********987 PP

>> MotA_activ  Transcription factor MotA, activation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.0     0.024        14      31      65 ..      28      62 ..      16      71 .. 0.84
   2 ?    6.0   0.0     0.022        13      30      69 ..     100     137 ..      78     147 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.024
                B-HHHHHHT-TTS-HHHHHHHHHHHHHTTSEEEET CS
  MotA_activ 31 itaaevrevhpdlgnavvnsnigvlikkglveksg 65
                ita e+rev   lg+   +s++  +++   v+++g
  EEA21351.1 28 ITADELREVMRSLGQNPTESELQDIVNELDVDRTG 62
                9**************99999988877776666665 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.022
                 TB-HHHHHHT-TTS-HHHHHHHHHHHHHTTSEEEETTEEE CS
  MotA_activ  30 fitaaevrevhpdlgnavvnsnigvlikkglveksgdgli 69 
                  i+a e+r v   +g+ + +++i  +ik    +  gdg i
  EEA21351.1 100 TISADEMRRVMKSIGEDLTDAEIEEMIKEA--DTDGDGTI 137
                 5899************************86..56677776 PP

>> MgtE_N  MgtE intracellular N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.2    0.0012      0.68       7      66 ..       2      61 ..       1      76 [. 0.90
   2 ?    4.8   0.3     0.075        42      17      64 ..      85     132 ..      78     134 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.0012
                HHCHCCS-HHHHHHHHHHS-HHHHHHHHCTS-CCCCCHHHHCS-HHHHHHHHCCS-HHHH CS
      MgtE_N  7 aelleelpeeeraallrllpkeeaaevleeldedlqeeliealsdeelaelleeldsDda 66
                ae l e + +++++ +   +k+  +e+  +   ++ ++l ++ +++el+++++eld+D++
  EEA21351.1  2 AESLTEEQIARFREAFAVFDKDGNGEITADELREVMRSLGQNPTESELQDIVNELDVDRT 61
                777888888899999999*********999999*************************86 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.075
                 HHHHHHHHS-HHHHHHHHCTS-CCCCCHHHHCS-HHHHHHHHCCS-HH CS
      MgtE_N  17 eraallrllpkeeaaevleeldedlqeeliealsdeelaelleeldsD 64 
                 e +a ++  +++  + +  +   ++ +++ e+l+d+e++e++ e d+D
  EEA21351.1  85 ELRAAFEVFDQDGSGTISADEMRRVMKSIGEDLTDAEIEEMIKEADTD 132
                 556677777777777777777788899999*************99998 PP

>> Peptidase_M24  Metallopeptidase family M24
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0     0.096        54       7      43 ..      26      62 ..      25      91 .. 0.82
   2 ?    7.3   0.0     0.006       3.4       7      52 ..      99     142 ..      96     149 .] 0.81

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.096
                   HHHHHHHHHHHHHHHHTTCBHHHHHHHHHHHHHHHTT CS
  Peptidase_M24  7 ariasaaleavleaikpgvterelaaeieattlkrhg 43
                   ++i++  l++v++ + +  te el++++++  + r+g
     EEA21351.1 26 GEITADELREVMRSLGQNPTESELQDIVNELDVDRTG 62
                   578899999*****************99977566655 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.006
                    HHHHHHHHHHHHHHHHTTCBHHHHHHHHHHHHHHHTTTCEESSSSE CS
  Peptidase_M24   7 ariasaaleavleaikpgvterelaaeieattlkrhgarglafppi 52 
                    + i++  +++v++ i +  t +e++++i+++     g + + ++ +
     EEA21351.1  99 GTISADEMRRVMKSIGEDLTDAEIEEMIKEA--DTDGDGTIDYQEF 142
                    6789999**********************88..6666666666555 PP

>> ApbA_C  Ketopantoate reductase PanE/ApbA C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.0    0.0029       1.6      44      88 ..      13      55 ..       4      63 .. 0.89
   2 ?    2.3   0.0      0.31   1.8e+02      43      70 ..     102     129 ..      66     137 .. 0.86

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0029
      ApbA_C 44 lkEalavaeaegvelseerleeaveavlektaan.rsSMlqDveag 88
                ++Ea+av+ ++g   + e +++++++v++   +n + S lqD+ + 
  EEA21351.1 13 FREAFAVFDKDG---NGEITADELREVMRSLGQNpTESELQDIVNE 55
                68**********...8888999********9999999*****9886 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.31
      ApbA_C  43 llkEalavaeaegvelseerleeaveav 70 
                  ++E+ +v+++ g  l++ ++ee+++++
  EEA21351.1 102 SADEMRRVMKSIGEDLTDAEIEEMIKEA 129
                 5688899999999888888899998875 PP

>> DUF1296  Protein of unknown function (DUF1296)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       5.6   3.2e+03      19      32 ..      44      57 ..      29      64 .. 0.52
   2 ?   11.6   0.5   0.00042      0.24       5      39 ..     106     137 ..     103     141 .. 0.78

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 5.6
     DUF1296 19 hsdeeIyamLkecn 32
                 +++e  ++ +e +
  EEA21351.1 44 PTESELQDIVNELD 57
                44555555555544 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 0.00042
     DUF1296   5 vrkviqsikEivgkhsdeeIyamLkecnmDpneav 39 
                 +r+v +si E   + +d+eI +m+ke++ D + ++
  EEA21351.1 106 MRRVMKSIGE---DLTDAEIEEMIKEADTDGDGTI 137
                 5555555555...567**************99886 PP

>> Phage_tail_S  Phage virion morphogenesis family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0       2.5   1.4e+03      27      42 ..       1      16 [.       1      26 [. 0.86
   2 ?    0.2   0.0       1.1   6.1e+02      17      39 ..      30      52 ..      24      62 .. 0.76
   3 ?    8.6   0.0    0.0028       1.6      17      48 ..     103     134 ..      84     137 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 2.5
  Phage_tail_S 27 igeeLresqeqrfeaq 42
                  ++e L e+q  rf++ 
    EEA21351.1  1 MAESLTEEQIARFREA 16
                  799999******9975 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 1.1
  Phage_tail_S 17 ladrrplmraigeeLresqeqrf 39
                  ++++r++mr++g++  es  q +
    EEA21351.1 30 ADELREVMRSLGQNPTESELQDI 52
                  56889999999998766666555 PP

  == domain 3  score: 8.6 bits;  conditional E-value: 0.0028
  Phage_tail_S  17 ladrrplmraigeeLresqeqrfeaqkdPdGs 48 
                   +++ r++m++ige+L ++  + + +++d dG 
    EEA21351.1 103 ADEMRRVMKSIGEDLTDAEIEEMIKEADTDGD 134
                   57899**************9999999999996 PP

>> DUF1707  Domain of unknown function (DUF1707)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.0    0.0064       3.6      20      52 ..      24      56 ..      10      57 .. 0.93
   2 ?   -0.0   0.0       1.7   9.4e+02      22      33 ..      62      73 ..      60      91 .. 0.64
   3 ?    0.0   0.1       1.6   9.2e+02      21      34 ..      98     111 ..      84     128 .. 0.72
   4 ?   -0.8   0.0       2.9   1.6e+03      20      30 ..     133     143 ..     120     147 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0064
     DUF1707 20 aeGrLtldEfdeRleaalaArtrgeLaalvaDL 52
                ++G +t dE++e +    +  t +eL+++v  L
  EEA21351.1 24 GNGEITADELREVMRSLGQNPTESELQDIVNEL 56
                57**************************99987 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 1.7
     DUF1707 22 GrLtldEfdeRl 33
                G ++ dEf + +
  EEA21351.1 62 GTIDFDEFLTMM 73
                888888886655 PP

  == domain 3  score: 0.0 bits;  conditional E-value: 1.6
     DUF1707  21 eGrLtldEfdeRle 34 
                  G ++ dE+++ ++
  EEA21351.1  98 SGTISADEMRRVMK 111
                 57888888876555 PP

  == domain 4  score: -0.8 bits;  conditional E-value: 2.9
     DUF1707  20 aeGrLtldEfd 30 
                 ++G ++ +Ef 
  EEA21351.1 133 GDGTIDYQEFV 143
                 58999999985 PP

>> DED  Death effector domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.1      0.67   3.8e+02       2      17 ..      34      49 ..       1      86 [. 0.67
   2 ?    8.4   0.0    0.0047       2.7       2      20 ..     107     125 ..     106     127 .. 0.92

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.67
                HHHHHHHCCCS-HHHH CS
         DED  2 rkllleiseeLteeel 17
                r+++ +++++ te+el
  EEA21351.1 34 REVMRSLGQNPTESEL 49
                3344444444444444 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0047
                 HHHHHHHCCCS-HHHHHHH CS
         DED   2 rkllleiseeLteeelesL 20 
                 r+++ +i+e+Lt+ e+e++
  EEA21351.1 107 RRVMKSIGEDLTDAEIEEM 125
                 89***************98 PP

>> GPHH  Voltage-dependent L-type calcium channel, IQ-associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.0     0.042        24       1      29 [.      12      40 ..      12      42 .. 0.92
   2 ?   -2.5   0.0       7.8   4.4e+03      10      26 ..      57      73 ..      55      75 .. 0.75
   3 ?    1.9   0.0      0.34   1.9e+02       9      29 ..      93     113 ..      92     115 .. 0.88
   4 ?   -0.7   0.0       2.2   1.2e+03       8      27 ..     128     147 ..     128     148 .. 0.80

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.042
        GPHH  1 eFvrvWaeyDPeAtgrikvqdmyellrrl 29
                +F ++ a +D   +g i ++++ e++r+l
  EEA21351.1 12 RFREAFAVFDKDGNGEITADELREVMRSL 40
                688999******************99986 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 7.8
        GPHH 10 DPeAtgrikvqdmyell 26
                D   tg+i  ++ ++++
  EEA21351.1 57 DVDRTGTIDFDEFLTMM 73
                55668999999998886 PP

  == domain 3  score: 1.9 bits;  conditional E-value: 0.34
        GPHH   9 yDPeAtgrikvqdmyellrrl 29 
                 +D   +g+i++++m  +++++
  EEA21351.1  93 FDQDGSGTISADEMRRVMKSI 113
                 89999*********9998876 PP

  == domain 4  score: -0.7 bits;  conditional E-value: 2.2
        GPHH   8 eyDPeAtgrikvqdmyellr 27 
                 e D    g+i +q+ + l+ 
  EEA21351.1 128 EADTDGDGTIDYQEFVHLMT 147
                 568888999***99998875 PP

>> DUF533  Protein of unknown function (DUF533)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.1      0.24   1.3e+02      85     114 ..      25      54 ..      23      59 .. 0.89
   2 ?    6.2   0.9     0.013       7.1      86     115 ..      99     128 ..      86     145 .. 0.91

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.24
      DUF533  85 DGhideeErqrIlqeleelgldaeekalle 114
                 +G+i ++E + ++++l++  +++e +++++
  EEA21351.1  25 NGEITADELREVMRSLGQNPTESELQDIVN 54 
                 69*****************99999998886 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.013
      DUF533  86 GhideeErqrIlqeleelgldaeekalled 115
                 G i+++E++r++++++e+ +dae ++++++
  EEA21351.1  99 GTISADEMRRVMKSIGEDLTDAEIEEMIKE 128
                 99****************999999998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (149 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       918  (0.051202); expected 358.6 (0.02)
Passed bias filter:                      694  (0.0387082); expected 358.6 (0.02)
Passed Vit filter:                        76  (0.00423894); expected 17.9 (0.001)
Passed Fwd filter:                        32  (0.00178482); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              32  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.43
# Mc/sec: 1038.45
//
Query:       EEA21352.1  [L=113]
Description: calmodulin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.1e-30  102.0   7.4    7.6e-11   40.8   0.2    3.1  3  EF-hand_1        EF hand
    7.2e-26   89.8   6.6    4.1e-14   52.2   0.7    3.0  3  EF-hand_8        EF-hand domain pair
    1.7e-25   89.3   3.7    3.2e-17   62.8   0.7    2.0  2  EF-hand_7        EF-hand domain pair
    1.5e-22   77.5   3.3      6e-08   32.0   0.0    3.2  3  EF-hand_6        EF-hand domain
    2.6e-18   64.6   4.9    6.7e-07   28.5   0.0    3.3  3  EF-hand_5        EF hand
    8.8e-13   48.4   0.9    1.3e-05   25.4   0.1    2.1  2  EF-hand_9        EF-hand domain
    5.6e-09   35.9   0.6     0.0002   21.3   0.1    2.1  2  EF-hand_4        Cytoskeletal-regulatory complex EF hand
    7.3e-06   26.8   0.0    0.00047   21.0   0.0    2.0  2  EF-hand_11       EF-hand domain
    0.00059   20.1   0.1     0.0053   17.1   0.0    1.9  2  SPARC_Ca_bdg     Secreted protein acidic and rich in cysteine
     0.0014   17.2   0.0     0.0015   17.1   0.0    1.0  1  DUF5580          Family of unknown function (DUF5580)
      0.003   17.4   0.3     0.0066   16.3   0.1    1.7  2  EF-hand_10       EF hand
     0.0034   17.4   0.0        2.9    8.0   0.0    2.2  2  UPF0154          Uncharacterised protein family (UPF0154)
  ------ inclusion threshold ------
      0.019   15.2   0.6       0.11   12.7   0.1    2.1  2  Dockerin_1       Dockerin type I domain
      0.027   15.0   0.2        1.9    9.1   0.0    2.5  2  FGAR-AT_linker   Formylglycinamide ribonucleotide amidotransf
      0.031   14.2   1.0       0.13   12.2   0.5    1.9  2  TerB             Tellurite resistance protein TerB
      0.051   13.7   0.6       0.11   12.6   0.3    1.7  2  DUF1296          Protein of unknown function (DUF1296)
      0.069   13.5   0.2       0.54   10.6   0.0    2.0  2  EF-hand_14       EF-hand domain
      0.098   12.5   3.7          7    6.6   0.3    3.5  3  Glycos_trans_3N  Glycosyl transferase family, helical bundle 
       0.11   12.9   0.5       0.35   11.2   0.1    1.9  2  DUF1456          Protein of unknown function (DUF1456)


Domain annotation for each model (and alignments):
>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.9   0.6   2.4e-10   2.3e-07       1      28 [.      12      39 ..      12      40 .. 0.94
   2 !   34.8   0.0   6.3e-12   5.9e-09       1      28 [.      49      76 ..      49      77 .. 0.96
   3 !   40.8   0.2     8e-14   7.6e-11       1      28 [.      85     112 ..      85     113 .] 0.96

  Alignments for each domain:
  == domain 1  score: 29.9 bits;  conditional E-value: 2.4e-10
                HHHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1  1 elkeiFrefDkDgdGkIdfeEfkellkk 28
                el++i +e+D+D++G+Idf+Ef++++ +
  EEA21352.1 12 ELQDIVNELDVDRTGTIDFDEFLTMMVH 39
                799***********************75 PP

  == domain 2  score: 34.8 bits;  conditional E-value: 6.3e-12
                HHHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1  1 elkeiFrefDkDgdGkIdfeEfkellkk 28
                el+ +F++fD+Dg+G+I+ +E+++++k+
  EEA21352.1 49 ELRAAFEVFDQDGSGTISADEMRRVMKS 76
                799***********************98 PP

  == domain 3  score: 40.8 bits;  conditional E-value: 8e-14
                 HHHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1   1 elkeiFrefDkDgdGkIdfeEfkellkk 28 
                 e++e+++e+D+DgdG+Id++Ef++l+++
  EEA21352.1  85 EIEEMIKEADTDGDGTIDYQEFVHLMTH 112
                 79************************86 PP

>> EF-hand_8  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.4   0.1     3e-11   2.9e-08      14      54 ..       1      39 [.       1      40 [. 0.95
   2 !   15.4   0.1   1.3e-05     0.012      25      47 ..      47      69 ..      41      70 .. 0.90
   3 !   52.2   0.7   4.3e-17   4.1e-14       2      54 ..      62     112 ..      62     113 .] 0.94

  Alignments for each domain:
  == domain 1  score: 33.4 bits;  conditional E-value: 3e-11
   EF-hand_8 14 lrilglkkglseeevdilfrefDtdgdGkisfeEFcvller 54
                +r+lg++   +e+e++++++e+D d+ G+i+f+EF+ ++++
  EEA21352.1  1 MRSLGQN--PTESELQDIVNELDVDRTGTIDFDEFLTMMVH 39
                5789999..******************************98 PP

  == domain 2  score: 15.4 bits;  conditional E-value: 1.3e-05
   EF-hand_8 25 eeevdilfrefDtdgdGkisfeE 47
                e e+++ f  fD+dg+G+is +E
  EEA21352.1 47 EAELRAAFEVFDQDGSGTISADE 69
                6689****************988 PP

  == domain 3  score: 52.2 bits;  conditional E-value: 4.3e-17
   EF-hand_8   2 kgkItreelrrilrilglkkglseeevdilfrefDtdgdGkisfeEFcvller 54 
                 +g I+ +e+rr ++++g    l++ e++++++e+DtdgdG+i++ EF+ l+++
  EEA21352.1  62 SGTISADEMRRVMKSIGED--LTDAEIEEMIKEADTDGDGTIDYQEFVHLMTH 112
                 589**********888977..******************************98 PP

>> EF-hand_7  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.9   0.1   2.6e-09   2.5e-06      36      70 ..       3      37 ..       1      38 [. 0.92
   2 !   62.8   0.7   3.3e-20   3.2e-17       2      70 ..      48     110 ..      47     111 .. 0.96

  Alignments for each domain:
  == domain 1  score: 27.9 bits;  conditional E-value: 2.6e-09
   EF-hand_7 36 gegsklsdeelellfkefDtdkdGvisfdEFlkly 70
                + g ++++ el+++++e+D d+ G+i+fdEFl+++
  EEA21352.1  3 SLGQNPTESELQDIVNELDVDRTGTIDFDEFLTMM 37
                568889**************************998 PP

  == domain 2  score: 62.8 bits;  conditional E-value: 3.3e-20
   EF-hand_7   2 eklkeaFkelDtdgdgyldkeellrllrkifqgagegsklsdeelellfkefDtdkdGvisfdEFlkly 70 
                  +l+ aF+ +D+dg+g ++ +e++r+++      + g++l+d e+e+++ke Dtd+dG+i+++EF++l+
  EEA21352.1  48 AELRAAFEVFDQDGSGTISADEMRRVMK------SIGEDLTDAEIEEMIKEADTDGDGTIDYQEFVHLM 110
                 57999***********************......9********************************99 PP

>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5   0.2   6.9e-08   6.5e-05       1      27 [.      12      38 ..      12      43 .. 0.91
   2 !   32.0   0.0   6.3e-11     6e-08       1      31 []      49      78 ..      49      78 .. 0.94
   3 !   22.6   0.1   6.6e-08   6.2e-05       2      27 ..      86     111 ..      85     113 .] 0.88

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 6.9e-08
   EF-hand_6  1 elreaFklfDkdgdGkidaeElrkalr 27
                el+++ +++D+d++G+id++E+  ++ 
  EEA21352.1 12 ELQDIVNELDVDRTGTIDFDEFLTMMV 38
                68999*****************99985 PP

  == domain 2  score: 32.0 bits;  conditional E-value: 6.3e-11
   EF-hand_6  1 elreaFklfDkdgdGkidaeElrkalrkalg 31
                elr+aF+ fD+dg+G+i+a+E+r++++ + g
  EEA21352.1 49 ELRAAFEVFDQDGSGTISADEMRRVMK-SIG 78
                79************************9.765 PP

  == domain 3  score: 22.6 bits;  conditional E-value: 6.6e-08
   EF-hand_6   2 lreaFklfDkdgdGkidaeElrkalr 27 
                 ++e  k+ D+dgdG+id++E++++++
  EEA21352.1  86 IEEMIKEADTDGDGTIDYQEFVHLMT 111
                 66777899***************998 PP

>> EF-hand_5  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.2   0.3   5.2e-05     0.049       6      25 .]      18      37 ..      11      38 .. 0.89
   2 !   28.5   0.0   7.1e-10   6.7e-07       1      25 []      50      74 ..      50      74 .. 0.94
   3 !   24.0   0.1     2e-08   1.9e-05       2      24 ..      87     109 ..      86     110 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 5.2e-05
                HHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5  6 qaiDlNgDGkIskeELktlv 25
                +++D+++ G+I+++E+ t++
  EEA21352.1 18 NELDVDRTGTIDFDEFLTMM 37
                689*************9976 PP

  == domain 2  score: 28.5 bits;  conditional E-value: 7.1e-10
                HHHHHHHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5  1 lkdtFqaiDlNgDGkIskeELktlv 25
                l+++F+ +D +g+G+Is++E ++++
  EEA21352.1 50 LRAAFEVFDQDGSGTISADEMRRVM 74
                6899******************987 PP

  == domain 3  score: 24.0 bits;  conditional E-value: 2e-08
                 HHHHHHH-SS-SSCE-HHHHHHH CS
   EF-hand_5   2 kdtFqaiDlNgDGkIskeELktl 24 
                 +++ +++D++gDG+I+ +E+  l
  EEA21352.1  87 EEMIKEADTDGDGTIDYQEFVHL 109
                 667899**************766 PP

>> EF-hand_9  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.1   0.1   1.5e-07   0.00015      28      63 ..       5      38 ..       1      40 [. 0.90
   2 !   25.4   0.1   1.3e-08   1.3e-05       3      63 ..      53     111 ..      51     113 .] 0.96

  Alignments for each domain:
  == domain 1  score: 22.1 bits;  conditional E-value: 1.5e-07
   EF-hand_9 28 taqdpeeseLeelakelDPdgedasvdldtflrvmr 63
                ++ +p+eseL++  +elD d   +++d+d fl++m 
  EEA21352.1  5 GQ-NPTESELQDIVNELDVDRT-GTIDFDEFLTMMV 38
                55.9****************99.***********95 PP

  == domain 2  score: 25.4 bits;  conditional E-value: 1.3e-08
   EF-hand_9   3 vFevcDtqktGrVpvsrlidyLravtaqdpeeseLeelakelDPdgedasvdldtflrvmr 63 
                  Fev+D +  G++   ++  +++  ++ d +++e+ee  ke+D dg  +++d   f + m 
  EEA21352.1  53 AFEVFDQDGSGTISADEMRRVMKSIGE-DLTDAEIEEMIKEADTDGD-GTIDYQEFVHLMT 111
                 7**************************.******************9.***********96 PP

>> EF-hand_4  Cytoskeletal-regulatory complex EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.3   0.1   6.3e-05     0.059      42      69 ..      10      37 ..       5      40 .. 0.88
   2 !   21.3   0.1   2.1e-07    0.0002       5      69 ..      46     110 ..      43     112 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 6.3e-05
   EF-hand_4 42 edklekiwdladidedgkldfeefciam 69
                e++l+ i +  d+d  g++df+ef  +m
  EEA21352.1 10 ESELQDIVNELDVDRTGTIDFDEFLTMM 37
                67899999999*************9887 PP

  == domain 2  score: 21.3 bits;  conditional E-value: 2.1e-07
   EF-hand_4   5 eeleikkyweifsglkpednkltgdkvapvlkn..skleedklekiwdladidedgkldfeefciam 69 
                 ee e++  +e+f   ++ + +++ d++  v+k+    l++ ++e++ + ad d dg++d++ef+  m
  EEA21352.1  46 EEAELRAAFEVFD--QDGSGTISADEMRRVMKSigEDLTDAEIEEMIKEADTDGDGTIDYQEFVHLM 110
                 6778888888887..567889**********984458**************************9877 PP

>> EF-hand_11  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.0     0.045        42      54      85 ..       9      40 ..       4      49 .. 0.80
   2 !   21.0   0.0   4.9e-07   0.00047      22      81 ..      50     109 ..      35     113 .] 0.86

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.045
                -HHHHHHHHHTS-B-TTS-EEHHHHHHHHCS- CS
  EF-hand_11 54 tdeqfdrlwselpvnakgrlkyqdflsklsie 85
                t+ +++ + +el v+  g + +++fl+ +  +
  EEA21352.1  9 TESELQDIVNELDVDRTGTIDFDEFLTMMVHK 40
                56677788999999999999999999877654 PP

  == domain 2  score: 21.0 bits;  conditional E-value: 4.9e-07
                 HHHHHHHH-TT-SSEE-HHHHHHHHHHHT----HHHHHHHHHTS-B-TTS-EEHHHHHHH CS
  EF-hand_11  22 ivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsk 81 
                 +   fe fd   s t+s +e+r + +   + ltd +++ + +e   +  g + yq+f+  
  EEA21352.1  50 LRAAFEVFDQDGSGTISADEMRRVMKSIGEDLTDAEIEEMIKEADTDGDGTIDYQEFVHL 109
                 5568**********************999****************************865 PP

>> SPARC_Ca_bdg  Secreted protein acidic and rich in cysteine Ca binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.0      0.46   4.3e+02      87     111 ..      10      34 ..       3      36 .. 0.79
   2 !   17.1   0.0   5.6e-06    0.0053      55     112 ..      49     108 ..      35     109 .. 0.85

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.46
  SPARC_Ca_bdg  87 ehCikpflescDadkdkkislkEwc 111
                   e+  +  +++ D+d+ ++i+  E+ 
    EEA21352.1  10 ESELQDIVNELDVDRTGTIDFDEFL 34 
                   5556778899999999999999986 PP

  == domain 2  score: 17.1 bits;  conditional E-value: 5.6e-06
  SPARC_Ca_bdg  55 pvawkFsklDtnsdkvlsksELaplrapl..vklehCikpflescDadkdkkislkEwce 112
                   +++  F+ +D++  +++s  E++ + +++  + ++  i+++++++D+d d++i+ +E+++
    EEA21352.1  49 ELRAAFEVFDQDGSGTISADEMRRVMKSIgeDLTDAEIEEMIKEADTDGDGTIDYQEFVH 108
                   5667899****************99998844567889********************975 PP

>> DUF5580  Family of unknown function (DUF5580)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   0.0   1.6e-06    0.0015     302     386 ..      27     111 ..       3     113 .] 0.86

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 1.6e-06
     DUF5580 302 nkslleiLkmalktakgklnlenLnlsFrkeDrsfsGlLpppkvraiCgkhglyltlslletllnhqdlgyqdeikWqnfvelLs 386
                 + ++ e L m +++ k+  +  +L+ +F   D+  sG+++  ++r + +  g  lt + +e +++  d    + i +q+fv+l++
  EEA21352.1  27 TIDFDEFLTMMVHKGKATDEEAELRAAFEVFDQDGSGTISADEMRRVMKSIGEDLTDAEIEEMIKEADTDGDGTIDYQEFVHLMT 111
                 3367789999999999999999************************************************************986 PP

>> EF-hand_10  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       3.6   3.4e+03       6      17 ..      12      23 ..      10      36 .. 0.60
   2 !   16.3   0.1     7e-06    0.0066       2      46 ..      65     109 ..      64     112 .. 0.94

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 3.6
  EF-hand_10  6 EvkrlLreiNie 17
                E++++  e+ ++
  EEA21352.1 12 ELQDIVNELDVD 23
                555555554444 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 7e-06
  EF-hand_10   2 msfkEvkrlLreiNievddeYAekLFkkcDkSksgrLegeEieeF 46 
                 +s +E++r ++ i  ++ d   e++ k++D+  +g+++ +E+++ 
  EEA21352.1  65 ISADEMRRVMKSIGEDLTDAEIEEMIKEADTDGDGTIDYQEFVHL 109
                 5889**************************************986 PP

>> UPF0154  Uncharacterised protein family (UPF0154)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.3   0.0    0.0052       4.9      39      57 ..       1      19 [.       1      21 [. 0.90
   2 !    8.0   0.0    0.0031       2.9      30      57 ..      65      92 ..      62      94 .. 0.92

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0052
     UPF0154 39 mkqmGrkPSekqikqvmrs 57
                m++ G++P+e+ ++ ++++
  EEA21352.1  1 MRSLGQNPTESELQDIVNE 19
                899***********99986 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0031
     UPF0154 30 inekmirammkqmGrkPSekqikqvmrs 57
                i+++ +r  mk+ G  ++ + i++++++
  EEA21352.1 65 ISADEMRRVMKSIGEDLTDAEIEEMIKE 92
                89999********************875 PP

>> Dockerin_1  Dockerin type I domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0      0.69   6.5e+02      34      46 ..      17      29 ..       5      38 .. 0.73
   2 ?   12.7   0.1   0.00012      0.11       2      50 ..      57     106 ..      56     112 .. 0.88

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.69
                HGGGSTT-SSCES CS
  Dockerin_1 34 gkaaDvNgDGrvn 46
                 + +Dv++ G+++
  EEA21352.1 17 VNELDVDRTGTID 29
                5677888888876 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 0.00012
                 TETTSSSC-SHHHHHHHHHHCT.SSEBTTSCCCHGGGSTT-SSCESHHHH CS
  Dockerin_1   2 gDVNgDgkVnalDalliinyln.qregqssssngkaaDvNgDGrvnalDa 50 
                 +D +g+g+++a  + ++ + +  + ++ + +++ k aD +gDG+++   +
  EEA21352.1  57 FDQDGSGTISADEMRRVMKSIGeDLTDAEIEEMIKEADTDGDGTIDYQEF 106
                 5889999999999999999999888999999**************97665 PP

>> FGAR-AT_linker  Formylglycinamide ribonucleotide amidotransferase linker domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0      0.11     1e+02      26      37 ..       3      14 ..       1      16 [. 0.87
   2 ?    9.1   0.0     0.002       1.9      12      37 ..      65      87 ..      55      90 .. 0.90

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.11
  FGAR-AT_linker 26 klgrnPtdvEle 37
                    +lg+nPt  El+
      EEA21352.1  3 SLGQNPTESELQ 14
                    69********96 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.002
  FGAR-AT_linker 12 LsdeEidylqeafeklgrnPtdvEle 37
                    +s +E++++ +    +g++ td+E+e
      EEA21352.1 65 ISADEMRRVMKS---IGEDLTDAEIE 87
                    689*********...9********97 PP

>> TerB  Tellurite resistance protein TerB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.1      0.32     3e+02      65     110 ..      11      56 ..       5      62 .. 0.63
   2 ?   12.2   0.5   0.00014      0.13      42      91 ..      63     110 ..      39     113 .] 0.88

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.32
        TerB  65 eeakallelfeeaeeeavdleqftralkrklspeqrraliealwei 110
                  e+++++ + +  ++ ++d+++f   +  k +  + +a ++a +e+
  EEA21352.1  11 SELQDIVNELDVDRTGTIDFDEFLTMMVHKGKATDEEAELRAAFEV 56 
                 5666677777777777788887777666665555555555555555 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 0.00014
        TerB  42 gqvsesErqafrellksrfglspeeakallelfeeaeeeavdleqftral 91 
                 g++s++E++++++ +    +l+++e+++ +++++   + ++d+++f+  +
  EEA21352.1  63 GTISADEMRRVMKSI--GEDLTDAEIEEMIKEADTDGDGTIDYQEFVHLM 110
                 789************..88999************************9765 PP

>> DUF1296  Protein of unknown function (DUF1296)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       6.5   6.1e+03      23      32 ..      12      21 ..       5      28 .. 0.56
   2 ?   12.6   0.3   0.00012      0.11       5      39 ..      70     101 ..      66     106 .. 0.79

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 6.5
     DUF1296 23 eIyamLkecn 32
                e  ++ +e +
  EEA21352.1 12 ELQDIVNELD 21
                4444444444 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 0.00012
     DUF1296   5 vrkviqsikEivgkhsdeeIyamLkecnmDpneav 39 
                 +r+v +si E   + +d+eI +m+ke++ D + ++
  EEA21352.1  70 MRRVMKSIGE---DLTDAEIEEMIKEADTDGDGTI 101
                 5555555555...567**************99986 PP

>> EF-hand_14  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0      0.59   5.6e+02       7      31 ..      18      42 ..      13      47 .. 0.75
   2 ?   10.6   0.0   0.00057      0.54       6      45 ..      54      93 ..      50     109 .. 0.91

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.59
  EF-hand_14  7 dlfkdeetdklsvakllkaLaetGi 31
                + ++ + t+++ + ++l+++ ++G 
  EEA21352.1 18 NELDVDRTGTIDFDEFLTMMVHKGK 42
                345558899999*****99999985 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00057
  EF-hand_14  6 fdlfkdeetdklsvakllkaLaetGirkdDpRLkellkkl 45
                f++f++++++++s  ++ +++++ G   +D  ++e++k+ 
  EEA21352.1 54 FEVFDQDGSGTISADEMRRVMKSIGEDLTDAEIEEMIKEA 93
                9***********************************9975 PP

>> Glycos_trans_3N  Glycosyl transferase family, helical bundle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.2      0.26   2.4e+02      38      51 ..      33      46 ..       4      56 .. 0.57
   2 ?    6.1   0.1      0.01       9.8       9      34 ..      60      85 ..      58      86 .. 0.79
   3 ?    6.6   0.3    0.0074         7      10      24 ..      78      92 ..      75     105 .. 0.85

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.26
                     HHHHHHHH---HHH CS
  Glycos_trans_3N 38 fLmAlrlkGetaeE 51
                     fL+ +  kG   +E
       EEA21352.1 33 FLTMMVHKGKATDE 46
                     44444444422222 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.01
                     TT..---HHHHHHHHHHHHTTSS-HHH CS
  Glycos_trans_3N  9 dg.eeLtaeeirfaihgilkgevtdaq 34
                     dg ++ +a+e+r +++ i + ++tda+
       EEA21352.1 60 DGsGTISADEMRRVMKSIGE-DLTDAE 85
                     67689***********9977.556665 PP

  == domain 3  score: 6.6 bits;  conditional E-value: 0.0074
                     T.---HHHHHHHHHH CS
  Glycos_trans_3N 10 geeLtaeeirfaihg 24
                     ge+Lt++ei+++i++
       EEA21352.1 78 GEDLTDAEIEEMIKE 92
                     79***********87 PP

>> DUF1456  Protein of unknown function (DUF1456)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       2.9   2.7e+03      23      40 ..      38      55 ..      28      62 .. 0.62
   2 ?   11.2   0.1   0.00037      0.35      14      54 ..      65     105 ..      64     111 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 2.9
     DUF1456 23 fklggvevtkeelsalLk 40
                + +g  + +++el+a + 
  EEA21352.1 38 VHKGKATDEEAELRAAFE 55
                555556666666666654 PP

  == domain 2  score: 11.2 bits;  conditional E-value: 0.00037
     DUF1456  14 lkdedmveifklggvevtkeelsalLkkedeegyeeckdqv 54 
                 ++ ++m +++k+ g  +t +e+++++k+ d +g   ++ q 
  EEA21352.1  65 ISADEMRRVMKSIGEDLTDAEIEEMIKEADTDGDGTIDYQE 105
                 7899***********************99988766666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (113 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       802  (0.044732); expected 358.6 (0.02)
Passed bias filter:                      610  (0.0340231); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              19  [number of targets reported over threshold]
# CPU time: 0.41u 0.27s 00:00:00.68 Elapsed: 00:00:00.40
# Mc/sec: 841.18
//
Query:       EEA21353.1  [L=547]
Description: fatty-acid amide hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.1e-95  319.4   0.0    5.1e-95  319.1   0.0    1.1  1  Amidase   Amidase


Domain annotation for each model (and alignments):
>> Amidase  Amidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  319.1   0.0   2.9e-99   5.1e-95       1     451 []      75     541 ..      75     541 .. 0.92

  Alignments for each domain:
  == domain 1  score: 319.1 bits;  conditional E-value: 2.9e-99
                 HHHHHHHHHHHHHHHHH--EEEEEHCCCCHHHHT---TTT.......TTTT-EEEEETTB--TTSB--TTSGGGTT-B-SS--HHHHHHHHTT-EEEEE CS
     Amidase   1 elveaflkrieavneklnalvtvfieealaqAakldkkra.rgkekgpLhGvPisvKDnidvkgvpttaGskalenypaekDatvverLkkaGavilgk 98 
                 e++++fl+r+  ++  +n++ ++++eeal++A+ ld++ a +gk+ gpLhG+P+s+K+++  kg  + +G+ a+ ++++e     +e+L +aGav++++
  EEA21353.1  75 EVTNSFLRRAGLAQRLVNCVTELMPEEALERAKYLDDYLAkHGKPIGPLHGLPVSIKEHLPMKGRTINCGFVAWWGRVSEVTYSGTEVLYNAGAVLYVR 173
                 79************************************************************************************************* PP

                 E--SGGG-SSSSTT-TT---BBTTCTCCB--SSSHHHHHHHHTTSSSCEEEEESSSTTHHHHHHCTSEEEE--TTSC--TTB-...-SSTTT-EEEEEE CS
     Amidase  99 TnmdefamgsstensvfgptrNPwdksrtpGGSSGGsAAavAaglvplaiGtDtGGSiRiPAsfcglvGlKPtygrvSragvv...alessldvvGpla 194
                 T+ ++ +m++ t+++++g t++P++++ t+GGSSGG++A+++++++ ++iGtD+GGSiR PA+ cg++Gl+Pt+ r+++a+     + + + +v+Gpl+
  EEA21353.1 174 TTQPQCLMHLATSSNLYGETVCPYNRQLTSGGSSGGEGALIGMRGSAVGIGTDIGGSIRSPAANCGIYGLRPTSSRFPYAKFAaahGPQGIPAVAGPLS 272
                 ***********************************************************************************99988999******** PP

                 SSHHHHHHHHHHHBS--TT-TTS----...HHHHHHHHCTT---TT-EEEEEGGGCSS---CCHHHHHHHHHHHHHC.TT-EEEEEE-CCGGGHHHHHH CS
     Amidase 195 rsvedlalllrvilgedpkdstssvip...eesedlaeelkkslkglriGvvkedgvasldpevqravekalkaLee.aGhevvevelpsleealslyy 289
                 +s   l+l++++++ + p+  + s +p   + + +   +++   k+l+iGv+++dgv++++p+v+ra+++++ +L+  aG+e+v+++++++++a++ + 
  EEA21353.1 273 TSRGGLRLIMKAAIDSKPWLTEPSLLPipwRDDVSHLDQVAG-GKKLKIGVLWDDGVVKPHPPVTRALNEVVSKLRGvAGVEIVDWKPYRHDYAWERIA 370
                 *******************99999999666333333333333.379*****************************97367****************999 PP

                 HHHHHHHHHHTTT-SSSSS---SS-SCCCCCCCHHHHCCS-HHHHHHHHHHHHHCSCCCCCCCHHHHHHHHHHHHHHHHHHCCC..............B CS
     Amidase 290 lilvaeassnlarylgvryerlsetkvlsellpksraellgeevkrrielgnyalsaeasskyylkaqkvrrllrrefakafee..............l 374
                  +++a++++                   +  + +   e+l++ +++ i  ++y+   +   +  +   + ++++++++a+++++              +
  EEA21353.1 371 SLYYADGAAD------------------NLEILAQGGEPLLPLTHHIITDNEYRKRLQI--EEIWSLMEKNTEYKKDYANVWNDtatgvdergiptgmV 449
                 9999999866..................3456778999999999999999997766553..445555556668************************** PP

                 SEEEEESSSSS--BCCCCCHHHCSHHHHHGCCTTT...HHHHHTT--EEEEECCCCT..................TECEEEEEEESTT-HHHHH CS
     Amidase 375 DvllsPtaptpaprlgekdktidsytvlynlldftavvvpvnlaglpalsvpagksed.................glPvGvqvigkafqeetlL 451
                 Dv+lsPt p +ap+l+++++  + yt+ +nlld++a+v+pv+ a+ + ++   g++ +                 ++Pv++q+ig++ ++e+++
  EEA21353.1 450 DVILSPTGPGAAPPLNQAKY--WGYTSQWNLLDYPAAVFPVTQAQPEVDKKEEGYEPRnskdefnyklyepelyrDAPVSLQLIGRPCEDEKVC 541
                 ******************87..68************************998888875568889****************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (547 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       288  (0.0160634); expected 358.6 (0.02)
Passed bias filter:                      273  (0.0152267); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 3490.23
//
Query:       EEA21354.1  [L=272]
Description: 4-hydroxybenzoate octaprenyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.5e-32  112.9  17.2    5.5e-32  111.1  17.1    1.9  1  UbiA           UbiA prenyltransferase family
  ------ inclusion threshold ------
       0.46   10.7   2.5       0.51   10.6   0.7    1.9  2  DUF2304        Uncharacterized conserved protein (DUF2304)
       0.69    9.8   4.3        3.3    7.7   0.1    3.3  3  Deltameth_res  Deltamethrin resistance


Domain annotation for each model (and alignments):
>> UbiA  UbiA prenyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.1  17.1   9.1e-36   5.5e-32       4     189 ..      52     270 ..      49     272 .] 0.86

  Alignments for each domain:
  == domain 1  score: 111.1 bits;  conditional E-value: 9.1e-36
        UbiA   4 palvg...lalaaggspdlllllllllgtl....laaaaanalNdyfDreiDadmertpnRPlvsGrispkealifaivllilgllll.alllnpltal 94 
                 p ++g   +a+ +g   +++++l + ++++    +++ aa+++Nd++D+e Da+++rt +RP+++G+isp +a++fa+  ++ ++++l ++  ++l  +
  EEA21354.1  52 PHAFGvlhAAIRTGA--PPSTVLYASMIMFagsfFFSNAAHIWNDLVDAELDAKVDRTSKRPIPRGAISPGAAFLFAVTQAMGAAWFLsYIPGGFLQGF 148
                 555665334444444..44556666666666678**************************************************999967777788888 PP

        UbiA  95 lgllallly.vvYtglrlKrrtllgtvvggiafglppllgwaa..vtgsl..........................sllalllalavflltwaialand 164
                 l +l  +l+ + Y+  + Kr+t+++++v+g++ +++ ++g  +  v+ ++                           + +++l++a  l+t+ ++++++
  EEA21354.1 149 LYALPNILAtIYYP--WAKRHTHFPQLVLGLCLAWGTIMGELMlgVGAFTvsvpaefwsvnwaqggfsfpslhitlEPSVMALFFAGTLWTVIYDTIYA 245
                 88887777758888..************************9997755555888***********************99999999999************ PP

        UbiA 165 lrdregDrkagiktlpvvlGrkaar 189
                 ++d++ D+k+gik+l+v++  ++ +
  EEA21354.1 246 HQDLQADLKVGIKSLAVLFQTRTKF 270
                 *******************887766 PP

>> DUF2304  Uncharacterized conserved protein (DUF2304)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.7   8.6e-05      0.51      41      81 ..      45      85 ..      34      91 .. 0.89
   2 ?   -2.0   0.0      0.71   4.2e+03      61      85 ..     221     245 ..     217     262 .. 0.57

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 8.6e-05
     DUF2304 41 livlslfpqiltvlanllGvgrgtnllfllgivfllvilfs 81
                 ++l+ fp+++ vl  ++ +g +++ +++++++++    f+
  EEA21354.1 45 GLFLIYFPHAFGVLHAAIRTGAPPSTVLYASMIMFAGSFFF 85
                6899****************************999877665 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.71
     DUF2304  61 grgtnllfllgivfllvilfslslk 85 
                    ++++ l++   l  +++ +  +
  EEA21354.1 221 TLEPSVMALFFAGTLWTVIYDTIYA 245
                 4455555555555555555555555 PP

>> Deltameth_res  Deltamethrin resistance
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.1   0.00055       3.3      23      46 ..      70      93 ..      69      94 .. 0.89
   2 ?    1.3   0.2     0.055   3.3e+02      23      49 ..     171     197 ..     163     200 .. 0.68
   3 ?   -0.2   0.1      0.15   9.2e+02      30      43 ..     229     242 ..     227     248 .. 0.79

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00055
  Deltameth_res 23 avLaaGiviligTialakesglin 46
                   +vL+a+ ++++g++++ ++  ++n
     EEA21354.1 70 TVLYASMIMFAGSFFFSNAAHIWN 93
                   69**************99987765 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.055
  Deltameth_res  23 avLaaGiviligTialakesglinlny 49 
                     +L++G+    gTi+   + g+  +  
     EEA21354.1 171 PQLVLGLCLAWGTIMGELMLGVGAFTV 197
                    589999999999998666666655555 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 0.15
  Deltameth_res  30 viligTialakesg 43 
                    ++++gT+ ++++  
     EEA21354.1 229 LFFAGTLWTVIYDT 242
                    79****99998865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (272 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       313  (0.0174578); expected 358.6 (0.02)
Passed bias filter:                      191  (0.0106531); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.47
# Mc/sec: 1738.83
//
Query:       EEA21355.1  [L=488]
Description: kinesin family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.6e-52  176.3   0.0    2.5e-29  102.2   0.0    2.1  2  Kinesin         Kinesin motor domain
    2.4e-12   47.0   0.0    4.5e-12   46.1   0.0    1.4  1  Microtub_bd     Microtubule binding
  ------ inclusion threshold ------
      0.058   13.7   0.0       0.14   12.4   0.0    1.6  1  baeRF_family11  Bacterial archaeo-eukaryotic release factor f


Domain annotation for each model (and alignments):
>> Kinesin  Kinesin motor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.2   0.0   4.3e-33   2.5e-29       1     217 [.      16     247 ..      16     264 .. 0.82
   2 !   72.0   0.0   6.6e-24     4e-20     230     327 ..     338     441 ..     316     445 .. 0.86

  Alignments for each domain:
  == domain 1  score: 102.2 bits;  conditional E-value: 4.3e-33
                 EE-SSSHHHHTTTTEBCEEEEC...TCTCEEEEEEEEECTTSCEEEEESEEEETTS-HHHHHHHHHHHHHHHHHTTSEEEEEEEESTTSSHHHHHTBC. CS
     Kinesin   1 RvRplnekekeeeeeeevevee...ekkeeekkskkenkeeeekkfkFdkvfdeeatqeevyeetakplvesvleGynatifaYGqtgsGKTyTmegk. 95 
                 R Rpl++ e+e  e   ++ ++   ++  + k+++++ +++ +++ +F  vf++e+++++vy+ +++p v +vl+G n++ faYG++gsGKT+T+ g  
  EEA21355.1  16 RWRPLSQPETELGEMYRTTLSDcrsQSVVSIKSQASTGERSWTSSAAFHTVFGPEDNNSKVYNVAIAPNVLKVLRGENCSFFAYGHSGSGKTHTILGYd 114
                 78999999998888877777663323333344445555566678899**************************************************98 PP

                 ..TTTSBSHHHHHHHHHHHHHHHCTTT.HEEEEEEEEEEEEEETTEEEETTSTTT.........TSTSSEBEEEECTT...SCCEEETTS--EEESSHH CS
     Kinesin  96 ..eeeeeGiipraleelFesikkekee.kekefsvkvsylEiYneeiyDLLeskk.........skkkkklkiredsk...kgevyvkgltevevksae 179
                   + +e G++  a ++lF+s+ +  e+  e+e+ +   ++E+ + + +DLL++++              k+  r +++    g+v v+ + ++++ ++e
  EEA21355.1 115 sqNIQELGLCLAAAKQLFDSLYSLDEKnGEQELGIGFRLFELRKKSAFDLLNHHSqchiregpdG----KVYFRGETEildGGKVRVRPIVQRQCWKFE 209
                 8777899*************98866541578899999***************9998887654320....33333332211134799************* PP

                 HHHHHHHHHHHHHTSTTSSCTSHHCCSEEEEEEEEEEE CS
     Kinesin 180 evlellekgeknrkvaetklneeSSRSHavftitleqk 217
                  +++ l+++  +r+++++++ ++SSR H v+++++ ++
  EEA21355.1 210 SFQQELAEALCQRATGSSSVHDQSSRTHVVLELEVVSQ 247
                 *********************************99876 PP

  == domain 2  score: 72.0 bits;  conditional E-value: 6.6e-24
                 EEEEEEEEEECCCHHHHSS......TCHHHHHHHHHHHHHHHHHHHHHHHHHHTCCTSTSCGGGSHHHHHTGGGHSSSSE..EEEEEEE-TBGGGHHHH CS
     Kinesin 230 sklnLvDLAGsErasktga......aegerlkEaaniNkSLlaLgrvisaLaekkkskhipYRdSkLTrlLqdsLgGnsk..tlmivtvspssenleet 320
                 +k+ +vDLAG E  +++g+      ++ ++++E+ +iN+ LlaL++v++a +++  +k ip+R S LT+ L+d +  +sk   +mivt+sp++e+++ t
  EEA21355.1 338 AKMVFVDLAGAEFHNENGTqlratrQTLQERQEGRQINTDLLALKEVMRAWSQS--QKRIPFRSSSLTMALRDHFMSTSKgnSIMIVTLSPAAEQYTAT 434
                 7999********777766656644455677899*********************..*******************97654338**************** PP

                 HHHHHHH CS
     Kinesin 321 lstlkfa 327
                 l++lk++
  EEA21355.1 435 LNSLKYS 441
                 ******7 PP

>> Microtub_bd  Microtubule binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.1   0.0   7.6e-16   4.5e-12      22     149 .]      11     165 ..       9     165 .. 0.80

  Alignments for each domain:
  == domain 1  score: 46.1 bits;  conditional E-value: 7.6e-16
                  -EEEEEEECCCS-T.................EEEETTT............TTTEEEE-SEEEECTTHCCCCCC.CCHHHHHHHHTT--EEEEEEES.. CS
  Microtub_bd  22 iRvfarvrpelesek................akikfpe.........eekkkkkefsFdrvfeseseqeevfe.eisqlvqsaldgynvcifaygqTG 93 
                  i vfar rp ++ e+                                 e++ + +  F  vf +e ++++v++  i+  v  +l+g n++ fayg+ G
   EEA21355.1  11 INVFARWRPLSQPETelgemyrttlsdcrsqS-----VvsiksqastGERSWTSSAAFHTVFGPEDNNSKVYNvAIAPNVLKVLRGENCSFFAYGHSG 103
                  889********998888888666665555541.....04444455666778888999*********999998746888999999************** PP

                  ..................ST-HCHHHHHHHHHHCCTSCCCCEE..EEEEEEEEESS-EEETT CS
  Microtub_bd  94 sGKtyTmeg....eeeeagmipraveeifetiselkekgwkye..ielqfveiynekvqDlL 149
                  sGKt+T+ g    + +e g    a +++f+ + +l+ek+ + e  i +++ e+  ++  DlL
   EEA21355.1 104 SGKTHTILGydsqNIQELGLCLAAAKQLFDSLYSLDEKNGEQElgIGFRLFELRKKSAFDLL 165
                  *********98877889999*************99987655441166777888888888887 PP

>> baeRF_family11  Bacterial archaeo-eukaryotic release factor family 11
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   2.4e-05      0.14      50      86 ..     298     334 ..     254     338 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2.4e-05
  baeRF_family11  50 sesgrlqgaegqkvrleqYarkvdkalrpvLagrdlP 86 
                     +++ r+++ae +k + e Y+ +v+++++ +L+ +  P
      EEA21355.1 298 KNQERIDAAEAEKAQFEAYVTAVEEEIEAILKASPFP 334
                     4589***************************998877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (488 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       651  (0.0363099); expected 358.6 (0.02)
Passed bias filter:                      523  (0.0291706); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.44
# Mc/sec: 3332.15
//
Query:       EEA21356.1  [L=154]
Description: hypothetical protein PMAA_051660 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (154 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       273  (0.0152267); expected 358.6 (0.02)
Passed bias filter:                      257  (0.0143343); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.27s 00:00:00.67 Elapsed: 00:00:00.43
# Mc/sec: 1071.35
//
Query:       EEA21357.1  [L=193]
Description: hypothetical protein PMAA_051670 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.3e-07   29.4  15.5    6.3e-07   29.4  15.5    1.6  2  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
        1.9    8.2   8.1        2.9    7.6   8.1    1.2  1  CitX      Apo-citrate lyase phosphoribosyl-dephospho-CoA tran


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.3      0.79   7.1e+03      27      31 ..      53      57 ..      50      60 .. 0.59
   2 !   29.4  15.5   7.1e-11   6.3e-07       1      38 [.      61      98 ..      61     100 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 0.79
                THHHC CS
     Zn_clus 27 nleCt 31
                +++Ct
  EEA21357.1 53 SCKCT 57
                45666 PP

  == domain 2  score: 29.4 bits;  conditional E-value: 7.1e-11
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfysessk 38
                ++C++C++++vKCd+ kP+CsnC + +  C+ y    +
  EEA21357.1 61 TGCITCKRRHVKCDEAKPHCSNCLRARRCCEGYATNAR 98
                58****************************99877666 PP

>> CitX  Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   8.1   0.00032       2.9     100     155 ..      32      85 ..      26      89 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.00032
        CitX 100 Ees.hplGrlfDlDVldadgkkisRkdlglkpRkCllCeepakeCarsrrHsveelq 155
                 Ees ++lGrl Dl V +++  ++s k +  ++  C+ C++   +C   + H  + l+
  EEA21357.1  32 EESvNKLGRLADLGVNQTK--ALSCK-CTQSRTGCITCKRRHVKCDEAKPHCSNCLR 85 
                 555499*********8665..67765.6678889**************999877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (193 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       710  (0.0396006); expected 358.6 (0.02)
Passed bias filter:                      285  (0.015896); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.45
# Mc/sec: 1290.75
//
Query:       EEA21358.1  [L=434]
Description: zinc metallopeptidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.4e-66  224.2   0.1    2.2e-66  223.6   0.1    1.3  1  WLM             WLM domain
    0.00094   18.5  21.4     0.0011   18.3   4.6    3.2  2  zf-RanBP        Zn-finger in Ran binding protein and others
     0.0027   17.8   3.2     0.0067   16.5   3.2    1.6  1  DUF45           Protein of unknown function DUF45
  ------ inclusion threshold ------
      0.013   16.1   3.0       0.32   11.6   0.3    2.4  2  Stc1            Stc1 domain
      0.071   13.2   9.0       0.88    9.6   9.1    2.2  2  DZR             Double zinc ribbon
      0.097   12.5   0.2       0.22   11.4   0.2    1.5  1  SprT-like       SprT-like family
       0.14   12.1   0.0       0.26   11.2   0.0    1.4  1  Peptidase_M54   Peptidase family M54
       0.15   12.4   5.7        2.5    8.5   0.9    2.8  2  C1_2            C1 domain


Domain annotation for each model (and alignments):
>> WLM  WLM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  223.6   0.1   9.9e-70   2.2e-66       3     190 ..       8     194 ..       6     195 .. 0.94

  Alignments for each domain:
  == domain 1  score: 223.6 bits;  conditional E-value: 9.9e-70
         WLM   3 iseikvlkkkpekeaalellkriakdvqpimkkhkfkVglLtElaPkeanlLGlNvnkGekieLrLRtdkddkeflpyesimgtllHELaHnvygpHda 101
                 + e+++ k++p++++al++l++ia+ v+pim+++ +kVg+L+E++P+++nlLGlN+n G+ki+LrLR ++d+ +flp+e++++t+lHEL+H+v+gpH++
  EEA21358.1   8 VLEYQHDKHRPREAEALHMLQKIASLVKPIMRQRSWKVGTLSEFYPSQRNLLGLNINAGQKICLRLRYPSDERQFLPLEQVVDTMLHELCHIVHGPHNR 106
                 6799*********************************************************************************************** PP

         WLM 102 kFyallkeLekeveelkakGlk.egflkeGkrlggkevrnksa.eeeeekealekagiagkgarlGgrseektrskasareliaaAaerRl 190
                 +F+al+++L++e+eel +kG++ egfl++Gkrlgg+++  ++a + ++ +++ +++ +ag+g++lGg       ++ + r++ia+Aa+rR+
  EEA21358.1 107 DFHALWNQLRDEHEELVIKGYTgEGFLSQGKRLGGRQIPLDEArRLARVAAEKRRTISAGSGQKLGGAPL---LKGSDVRKVIADAAQRRI 194
                 **************************************9998844455556666777899********99...89***************8 PP

>> zf-RanBP  Zn-finger in Ran binding protein and others
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   4.6   4.7e-07    0.0011       4      29 ..     315     340 ..     312     341 .. 0.95
   2 !    6.9   3.7    0.0017       3.8       3      13 ..     420     430 ..     418     430 .. 0.89

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 4.7e-07
                 SEE-SSS--EEESSSSB-TTT--BTS CS
    zf-RanBP   4 dWdCskClvqNfawstkCvaCqapkp 29 
                 +W+C  C++ N++  + C aC++++p
  EEA21358.1 315 SWNCQICTLENPPAYLCCDACGTERP 340
                 7***********************98 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0017
                 SSEE-SSS--E CS
    zf-RanBP   3 gdWdCskClvq 13 
                 ++W+Cs+C+++
  EEA21358.1 420 EWWTCSACGTM 430
                 69******986 PP

>> DUF45  Protein of unknown function DUF45
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   3.2     3e-06    0.0067     170     199 ..      92     121 ..      84     123 .. 0.90

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 3e-06
       DUF45 170 vvHElaHlleknHskrFwalvekllPdwke 199
                 ++HEl+H+++  H+++F al ++l ++ +e
  EEA21358.1  92 MLHELCHIVHGPHNRDFHALWNQLRDEHEE 121
                 58********************99888776 PP

>> Stc1  Stc1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.3   0.00014      0.32       9      72 ..     284     349 ..     280     357 .. 0.71
   2 ?    4.5   0.2     0.023        53      32      63 ..     400     432 ..     386     434 .] 0.71

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00014
                 EETTTS-H.HHHHTTTTEEEE-S-.......----TTTS-----E.EE-SSS--EEESTTS-HHHH CS
        Stc1   9 kplseFSk.kqlkklekklaeekakvkkakskikCkectakqate.leCsaCqktkpldeFsksqr 72 
                 kp  +F++   l+ + ++l ++ +++ + +   +C+ ct ++    l C+aC+  +p ++ + ++r
  EEA21358.1 284 KPIRRFASsGTLSSAYGTLDQNTENTIENDMSWNCQICTLENPPAyLCCDACGTERPAQSITAQSR 349
                 666666441456666777776655566666799******99766515666******9998877665 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.023
                 .......----TTTS-----E.EE-SSS--EEE CS
        Stc1  32 kvkkakskikCkectakqate.leCsaCqktkp 63 
                 +  k+  +  C+ c a   te  +CsaC+ +k+
  EEA21358.1 400 NRAKKPLGWLCHICGAFMETEwWTCSACGTMKT 432
                 3334444889****9998888579****99886 PP

>> DZR  Double zinc ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   9.1   0.00039      0.88       1      49 []     318     428 ..     318     428 .. 0.94
   2 ?    6.9   0.9    0.0028       6.3       1      20 [.     410     429 ..     410     433 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00039
         DZR   1 CpqCgeelppdarfCseCgtklkavaa..............................................................edrCpsCgek 37 
                 C+ C  e+pp    C++Cgt+ +a++                                                                  C  Cg+ 
  EEA21358.1 318 CQICTLENPPAYLCCDACGTERPAQSItaqsrlvvaaentsskratpkprsrlasqvitgddagrvvsfkgdtseritnldqnrakkplGWLCHICGAF 416
                 999******************65433367899*******************************************************9999******** PP

         DZR  38 vdpearfCpeCG 49 
                 ++ e+ +C +CG
  EEA21358.1 417 METEWWTCSACG 428
                 ***********9 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0028
         DZR   1 CpqCgeelppdarfCseCgt 20 
                 C  Cg+ ++ +  +Cs+Cgt
  EEA21358.1 410 CHICGAFMETEWWTCSACGT 429
                 67777777777777777777 PP

>> SprT-like  SprT-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.2   9.8e-05      0.22      62     102 ..      86     118 ..      67     130 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 9.8e-05
   SprT-like  62 drllntLaHElcHlalfvisgvrnnpHGaeFkawaakveka 102
                 +++++t++HElcH++     g    pH+++F+a+ +++ + 
  EEA21358.1  86 EQVVDTMLHELCHIVH----G----PHNRDFHALWNQLRDE 118
                 7899*********875....5....8999998888887665 PP

>> Peptidase_M54  Peptidase family M54
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   0.00012      0.26     100     164 ..      45     107 ..      24     120 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00012
                    EESS-EE-TT-S-BSEEE-SSSSEEEEE-T--.....SHHHHHHHHHHHHHHHHHHHTT----S- CS
  Peptidase_M54 100 lgsrdqyidiykkvlGievsiGnyavlalsikefytedkeLflervvkevlhelGhlyGLshCke 164
                    +g   ++ +  + +lG++++ G+   l l       e + L le+vv  +lhel h+   +h ++
     EEA21358.1  45 VGTLSEFYPSQRNLLGLNINAGQKICLRLRYP--SDERQFLPLEQVVDTMLHELCHIVHGPHNRD 107
                    66667788889999******999987777744..356667889*************988788665 PP

>> C1_2  C1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.9    0.0011       2.5      14      38 ..     311     335 ..     282     338 .. 0.78
   2 ?    5.4   0.3     0.011        24      19      39 ..     408     428 ..     396     432 .. 0.73

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.0011
        C1_2  14 dssesfnCsaCgrkidgffYsCseC 38 
                 + + s+nC++C  +  + +  C+ C
  EEA21358.1 311 ENDMSWNCQICTLENPPAYLCCDAC 335
                 56778*********54444555557 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.011
        C1_2  19 fnCsaCgrkidgffYsCseCd 39 
                 + C++Cg  ++ +  +Cs C 
  EEA21358.1 408 WLCHICGAFMETEWWTCSACG 428
                 678888888755558888885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (434 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       616  (0.0343577); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2932.50
//
Query:       EEA21359.1  [L=580]
Description: pentachlorophenol 4-monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.3e-68  230.5   0.0    4.1e-68  230.2   0.0    1.1  1  FAD_binding_3   FAD binding domain
      9e-06   25.5   0.2    6.3e-05   22.7   0.0    2.1  2  DAO             FAD dependent oxidoreductase
    4.5e-05   22.8   0.0    0.00019   20.8   0.0    1.9  1  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    0.00028   20.4   0.0    0.00055   19.4   0.0    1.4  1  FAD_oxidored    FAD dependent oxidoreductase
    0.00076   19.5   0.0     0.0018   18.3   0.0    1.7  1  Phe_hydrox_dim  Phenol hydroxylase, C-terminal dimerisation d
     0.0012   18.1   0.0     0.0028   16.9   0.0    1.5  1  Thi4            Thi4 family
     0.0015   17.4   0.0      0.003   16.5   0.0    1.5  2  Trp_halogenase  Tryptophan halogenase
     0.0068   16.6   0.1      0.021   15.0   0.0    1.8  2  NAD_binding_8   NAD(P)-binding Rossmann-like domain
     0.0089   14.8   0.0      0.077   11.7   0.0    2.0  2  HI0933_like     HI0933-like protein
     0.0095   15.1   0.0      0.021   13.9   0.0    1.6  2  FAD_binding_2   FAD binding domain
  ------ inclusion threshold ------
      0.087   13.4   0.0       0.21   12.2   0.0    1.6  1  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
       0.11   11.7   0.0       0.29   10.4   0.0    1.6  2  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
       0.12   11.4   0.0       0.26   10.3   0.0    1.6  1  GIDA            Glucose inhibited division protein A


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  230.2   0.0     3e-71   4.1e-68       1     347 [.      18     375 ..      18     377 .. 0.88

  Alignments for each domain:
  == domain 1  score: 230.2 bits;  conditional E-value: 3e-71
                    EEEEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSS..S--EEEHHHHHHHHHTT-HHHHHHHSEECCCCEEEEEEECCCC.....CEEEEE CS
  FAD_binding_3   1 etdVlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlp..radglnqrtmellrqlGledrilaegapnelmgealynelsdt.....pkarad 89 
                    +tdV + G+Gp+Gl++a +L+++G+++ lvek +++ + +  ra++l +rt+e++++l l d++ + g+   ++ ++  ++  ++     +k+  +
     EEA21359.1  18 KTDVFVCGGGPVGLITAYMLARHGISTYLVEKDDKEEQPSygRACTLYPRTLEMMEHLELLDTMNQAGYIARNSVTFKDGK--RVtargwHKIFDR 111
                    69*******************************999987777**************************9999988888888..3345677888888 PP

                    HHCHHCST-CEE--HHHHHHHHHHHHHHHT.EEETCSEE.....EECCEECCCCCCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHHHTGGEEEE CS
  FAD_binding_3  90 lelesspervtvypqteleriLvehaeerg.lqvrfkte.....vesleqdeegvtaevrdketgeeetvrakYlvGaDGgrStvrktlgiefege 179
                    +   +   +  ++ q++le i +++ ++ g + +  + +     v    +d+ +v  ++r+ +t+ee tvrakYlvGaDGg+S vr+ ++i+f+g+
     EEA21359.1 112 MRGGTYLDYCLNIRQKRLEDIFRKAYRKLGgIPL-GGWKlvsfqVDHESADDHKVVVQIRNVKTDEELTVRAKYLVGADGGKSLVRELAKIPFNGT 206
                    886688889999******************5554.444412222333467889999**************************************** PP

                    EEEEEEEEEEEEEEC-SCCCTTCCEEEEECCTTEEEEEECCETEEEEEEEEECCE-GGGSCCCHHHHHHHHHHHHHHTTSSCEE.EEEEEEEEEEE CS
  FAD_binding_3 180 etvyeagvldvlfdadlsdiveplvlilsaesrgvmviPlentlerfyvqvearaekeersekfteeevkarlreivgektldv.eieevsawtva 274
                    +t  ++  +d  f+++++d   +   i s++ + v  i le+  e+++ ++ +++  ++  + +tee++k+++ +++++ tld  ++++ +++ ++
     EEA21359.1 207 STQSRWVRVDGDFETNMPDSDIGFASIESKNHGNVVWIQLEK-GENRIGFALTDEMSAKYGNSMTEEDAKKEAIKAMEPFTLDIkNVSWWTVYCIQ 301
                    *99777777778888888555555555555555556677777.77788999999999999***********************999********** PP

                    EEEESSSEET.TEEE-GGGTEEE-STTSHHHHHHHHHHHHHHHHHHHHHTTSS-GGGGHHHHHHHHHHHHHHHH CS
  FAD_binding_3 275 qrvaekyrkg.rvflaGDAaHihpPtgGqGlNtaiqDavnLawkLaavlkGeAkeelLdtYeeerravaqavvd 347
                    qrvae++  + r++laGDA+H+h+  ++qG+Nt++ Da+nL wkLa  +kG+ ++e+L+tY++err  a+ +++
     EEA21359.1 302 QRVAETFIADdRILLAGDACHTHSSGAAQGMNTGVHDAYNLSWKLAGTIKGWYGKEVLQTYDSERRSTAEYLIE 375
                    *******9888*********************************************************998876 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   0.0   4.6e-08   6.3e-05       1      31 [.      20      52 ..      20      67 .. 0.88
   2 ?   -0.1   0.0      0.38   5.3e+02     177     270 ..     164     258 ..      64     337 .. 0.57

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 4.6e-08
                EEEEECTSHHHHHHHHHHHHTT..EEEEESSSS CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..Vtllekgdi 31
                dv + GGG +Gl tAy Lar+g  + l+ek+d 
  EEA21359.1 20 DVFVCGGGPVGLITAYMLARHGisTYLVEKDDK 52
                899***************************964 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.38
                 TCEEEEE.EECT.EEEEEEEEEEE--GGGHHHHHTTCTT.TSEEEEEEEEE..EEEEECCTHSTGS..GCSEEEEEEEETTTTEEEEEETTSEEEEEES CS
         DAO 177 gkvwgve.rttp.gendaadavVnaaGawsdllgllkel.dlpispvrgqv..lvlkplseklvsp..aailpvpetdddgrgvyvtprkdgrvlvGgt 268
                 + v++++ ++t+ + +++a+++V a G  s l+   +el ++p+ ++  q+  ++++   e +++p  + +++  e+ + g +v +    +g+ ++G  
  EEA21359.1 164 KVVVQIRnVKTDeELTVRAKYLVGADGGKS-LV---RELaKIPFNGTSTQSrwVRVDGDFE-TNMPdsDIGFASIESKNHGNVVWIQLE-KGENRIGFA 256
                 334444454555344444577888888886.55...3332346666666664455544433.333311244444434444444444444.355555544 PP

                 SE CS
         DAO 269 ad 270
                  +
  EEA21359.1 257 LT 258
                 32 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8   0.0   1.4e-07   0.00019       2      58 ..      20     113 ..      19     211 .. 0.69

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 1.4e-07
                  SEEEE--SHHHHHHHHHHHHHTS-EEEEE....TTHCHHHCSHHHHCHHHHHHHHHHHHH.................................H CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxx.................................x RF
  Pyr_redox_2   2 dvvviGgGpAGlaaaltlaqagakvtlve....legtclnggcllskallgvaedaeias.................................e 58 
                  dv v GgGp Gl +a  la++g+ ++lve    +e+   ++ c l++  l+++e+ e +                                  +
   EEA21359.1  20 DVFVCGGGPVGLITAYMLARHGISTYLVEkddkEEQPSYGRACTLYPRTLEMMEHLELLDtmnqagyiarnsvtfkdgkrvtargwhkifdrmR 113
                  89**************************99988888888999**************98888877766666666665555555555554444440 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.0     4e-07   0.00055       1      31 [.      20      50 ..      20      52 .. 0.96

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 4e-07
  FAD_oxidored  1 DvvVvGGgpaGvaAAiaAaraGakvlLveer 31
                  Dv V+GGgp G++ A+  ar+G ++ Lve++
    EEA21359.1 20 DVFVCGGGPVGLITAYMLARHGISTYLVEKD 50
                  9****************************97 PP

>> Phe_hydrox_dim  Phenol hydroxylase, C-terminal dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   1.3e-06    0.0018       1      82 [.     413     487 ..     413     544 .. 0.81

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 1.3e-06
  Phe_hydrox_dim   1 FtsGvgveYqpsllvaevkskqnlatglrpGrrlpsakVvrvaDanpvdlqdeipsdGrfRilvfagdlsdaeqksrlsala 82 
                     F  G+g++Yq++++     +k   a+ +  G r p a V       pv+l    +  G++ i++fag+ + +  +++l a a
      EEA21359.1 413 FNIGLGIQYQENII-----NKPPSAGMISAGSRAPDALVYPPGSHFPVRLFTLSRYIGKWTIILFAGQYELT--RAKLPAAA 487
                     677***********.....788999******************************************96533..23333333 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.0     2e-06    0.0028      12      49 ..      13      49 ..       7      61 .. 0.92

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 2e-06
                HHHHTEEEEEEE--SHHHHHHHHHHHHCTTS-EEEEES CS
        Thi4 12 llkyaesDvvivGaGssGLtaayylakkpdlkvailer 49
                l + +++Dv + G+G+ GL +ay+la++ ++ + ++e+
  EEA21359.1 13 LTDSVKTDVFVCGGGPVGLITAYMLARH-GISTYLVEK 49
                678899*********************9.999999986 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   2.2e-06     0.003       1      89 [.      20     106 ..      20     138 .. 0.79
   2 ?   -3.5   0.0       2.4   3.4e+03     186     219 ..     168     200 ..     155     216 .. 0.80

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 2.2e-06
                     EEEEE--SHHHHHHHHHHHHHTTTSSEEEEEE-...SSS---SS-EE--THHHHTHHHHT--HHHHCHHCT-EEE-EEEEESSSSCESEEEE CS
  Trp_halogenase   1 kivivGGGtaGwlaAaalakalkgklevtlves...eeigtvgvGeatipsirkllrlLgideeeflreteatfKlgikFedWgkkgeryih 89 
                     ++ + GGG+ G ++A +la+++   ++  lve+   ee + +g    + p + ++++ L++ +   ++++    + +++F+d ++ + r  h
      EEA21359.1  20 DVFVCGGGPVGLITAYMLARHG---ISTYLVEKddkEEQPSYGRACTLYPRTLEMMEHLELLDT--MNQAGYIARNSVTFKDGKRVTARGWH 106
                     5899******************...56666665111666666666678899999********99..**************998886555444 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 2.4
                     -EEEEEETTS-EEE-SEEEE-SGGG-IIIIIIT- CS
  Trp_halogenase 186 rveslrledgreveadlfiDcsGfrgllieqaLk 219
                     ++ +++++++ +v a   + + G ++l+ e a k
      EEA21359.1 168 QIRNVKTDEELTVRAKYLVGADGGKSLVRELA-K 200
                     58899999999999999999999999987765.4 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   1.5e-05     0.021       2      29 ..      24      51 ..      23      52 .. 0.92
   2 ?   -3.5   0.0         9   1.2e+04      24      53 ..      77     109 ..      73     111 .. 0.51

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.5e-05
                   E--SHHHHHHHHHHHCCTEEEEEE-SSS CS
  NAD_binding_8  2 vGaGlsGlvaAylLakagfdvlllekrd 29
                    G+G  Gl +Ay La++g++  l+ek d
     EEA21359.1 24 CGGGPVGLITAYMLARHGISTYLVEKDD 51
                   6***********************9986 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 9
                    EE-SSSSSSGGG-EECE...TT.CEECTS---EE CS
  NAD_binding_8  24 llekrdrlGGraasyev...pg.vrvdygahifh 53 
                    ll++ ++ G  +a+++v   +g ++   g+h ++
     EEA21359.1  77 LLDTMNQAGY-IARNSVtfkDGkRVTARGWHKIF 109
                    6666666643.33333334544244447777665 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.7   0.0   5.6e-05     0.077       2      34 ..      20      52 ..      19      55 .. 0.94
   2 ?    0.6   0.0      0.13   1.7e+02     140     167 ..     167     194 ..     149     197 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 5.6e-05
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SSSS CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVlllekakk 34
                 dv v GgG+ Gl +A  +a++g ++ l+ek +k
   EEA21359.1 20 DVFVCGGGPVGLITAYMLARHGISTYLVEKDDK 52
                 89***************************9876 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.13
                  TE.EEEEE.TTEEEEESEEEE----SS- CS
  HI0933_like 140 dgkfrvktkseeeleadklvlAtGGlSi 167
                   ++ +vkt++e +++a++lv A GG+S+
   EEA21359.1 167 VQIRNVKTDEELTVRAKYLVGADGGKSL 194
                  455678999999**************97 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   0.0   1.6e-05     0.021       1      33 [.      20      52 ..      20      88 .. 0.90
   2 ?   -3.8   0.0       3.6     5e+03     178     212 ..     166     200 ..     156     217 .. 0.64

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.6e-05
                   SEEEE--SHHHHHHHHHHHHTTT-EEEEESSSG CS
  FAD_binding_2  1 DviViGsGlAGLaAAleaaeaGlkvavvekeqe 33
                   Dv V+G+G  GL  A+ +a++G ++ +vek ++
     EEA21359.1 20 DVFVCGGGPVGLITAYMLARHGISTYLVEKDDK 52
                   999***************************876 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 3.6
                    EEEET..TTTCEEEEEESEEEE-----GG........ CS
  FAD_binding_2 178 vvenp..esgrevrirakavvlatgGfgrallkellg 212
                    vv+ +  ++ +e ++rak +v a gG +  l++el++
     EEA21359.1 166 VVQIRnvKTDEELTVRAKYLVGADGGKS--LVRELAK 200
                    4444444777777788888888877766..3555444 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00015      0.21       2      33 ..      21      52 ..      20      65 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00015
                EEEECSSHHHHHHHHHHHHTTSEEEEEESSSS CS
   Pyr_redox  2 vvvvGgGyiglElAgalaelgkkVtvversdk 33
                v v GgG +gl  A +la++g ++++ve  dk
  EEA21359.1 21 VFVCGGGPVGLITAYMLARHGISTYLVEKDDK 52
                7899************************9997 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   0.00021      0.29       2      30 ..      23      50 ..      21      93 .. 0.87
   2 ?   -2.7   0.0         2   2.8e+03     115     133 ..     171     190 ..     154     224 .. 0.69

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00021
  Pyr_redox_3  2 IiGaGPaGlaaaielkkagledylilEkg 30
                 + G+GP Gl +a+ l ++g+++y  +Ek+
   EEA21359.1 23 VCGGGPVGLITAYMLARHGISTY-LVEKD 50
                 67******************877.66775 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 2
  Pyr_redox_3 115 evetske.tyeAkkviiAtG 133
                  +v+t++e t++Ak+++ A G
   EEA21359.1 171 NVKTDEElTVRAKYLVGADG 190
                  46666666666666666655 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   0.00019      0.26       1      30 [.      20      49 ..      20      76 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00019
                CEEEE-SSHHHHHHHHHHHHTT--EEEEES CS
        GIDA  1 dviViGgGhAGceAAlaaarlGakvlLith 30
                dv V GgG  G+  A+ +ar G+++ L+ +
  EEA21359.1 20 DVFVCGGGPVGLITAYMLARHGISTYLVEK 49
                799************************933 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (580 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       483  (0.0269396); expected 358.6 (0.02)
Passed bias filter:                      464  (0.0258799); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.69u 0.30s 00:00:00.99 Elapsed: 00:00:00.48
# Mc/sec: 3602.28
//
Query:       EEA21360.1  [L=687]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (687 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       419  (0.02337); expected 358.6 (0.02)
Passed bias filter:                      261  (0.0145574); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 4843.04
//
Query:       EEA21361.1  [L=354]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (354 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       342  (0.0190752); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.24s 00:00:00.67 Elapsed: 00:00:00.40
# Mc/sec: 2648.54
//
Query:       EEA21362.1  [L=509]
Description: protein kinase, putative, partial [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      3e-15   56.3   0.0      3e-14   53.0   0.0    2.0  1  Pkinase      Protein kinase domain
    2.4e-05   23.7   0.1      0.088   12.1   0.0    2.1  2  Pkinase_Tyr  Protein tyrosine kinase


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.0   0.0   3.4e-18     3e-14      93     245 ..     290     492 ..     252     500 .. 0.78

  Alignments for each domain:
  == domain 1  score: 53.0 bits;  conditional E-value: 3.4e-18
                 SS--HHHHHHHHHHHHHHHHHHH.HTTEE-SS-SGGGEEEE.T....................................TTE...EEE-SGTTSEESSS CS
     Pkinase  93 gslseeeakkiakqilegleylH.skgiiHrDlKpeNiLid.e....................................kge...lKitDFGlakeles 150
                   l++  + +i+++++ +l+ylH + +iiH D+K +Ni++                                       k e     ++DFG a   + 
  EEA21362.1 290 HRLPSPVLAFILQRLFLALDYLHtECQIIHTDIKADNIMFGiAddsvfshfeeeelqrpvprkeidgriiykscelrmpK-EwsiPVLCDFGSAVPGDI 387
                 3477788999*************5566************9954799**********999999999888888877766642.157789*******88888 PP

                 SCSBCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHHHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCT........SHH...HHHTTS........ CS
     Pkinase 151 sskltsfvgtseYlAPEvlkeneyskkvDvWslGvilyelltgkppfsgekgkekvekeldqlekilkilg........etkeklpeasei........ 233
                 ++   + v    Y+A Ev+ e + + ++DvW +G+++++++ g  +f g++ + ++++   +l +i+ +lg        +         ++        
  EEA21362.1 388 EH--LEDVQPNIYRALEVILEVPWTYSIDVWNVGCMIWNIFEGGSLFTGQDPEFQTYRSRAHLAEIISLLGrppstllaP--------GQLtqkffsdd 476
                 66..67788899************************************98888888888888889999888653322221........22222444444 PP

                 ....-HHHHHHHHHHT CS
     Pkinase 234 ....seeakdllkkll 245
                      +ea+d+lk+ +
  EEA21362.1 477 grvdIKEAIDILKNTC 492
                 5555666666666665 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.0   5.7e-05      0.51      88     136 ..     280     329 ..     268     364 .. 0.89
   2 !   12.1   0.0   9.8e-06     0.088     164     203 ..     391     430 ..     368     450 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 5.7e-05
                  HHHHHHHTCTTTSBHHHHHHHHHHHHHHHHHHHHT.TEEEST-SGGGEEE CS
  Pkinase_Tyr  88 LlkfLrkkekekltlkdllsfalqvAkGmeyLesk.klvHrdlaarNvLl 136
                  +l+fL+++  ++l    l  + + +  +++yL+++ +++H d+ a N++ 
   EEA21362.1 280 VLTFLHRNPIHRLPSPVLAFILQRLFLALDYLHTEcQIIHTDIKADNIMF 329
                  67899999899999999999999999******97538***********96 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 9.8e-06
                  SSTSGGGGS-HHHHHHSEEEHHHHHHHHHHHHHHHHTTSS CS
  Pkinase_Tyr 164 eaklpvkWmapEslkekkftsksDvWsfGvllwEiftlge 203
                  e   p  + a+E++ e   t + DvW  G ++w if+ g+
   EEA21362.1 391 EDVQPNIYRALEVILEVPWTYSIDVWNVGCMIWNIFEGGS 430
                  556688899***************************9654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (509 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       412  (0.0229795); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.41
# Mc/sec: 3683.26
//
Query:       EEA21363.1  [L=214]
Description: hypothetical protein PMAA_051730 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (214 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       422  (0.0235373); expected 358.6 (0.02)
Passed bias filter:                      261  (0.0145574); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.23s 00:00:00.65 Elapsed: 00:00:00.40
# Mc/sec: 1588.44
//
Query:       EEA21364.1  [L=225]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.6e-11   43.6   0.0    3.5e-11   43.2   0.0    1.1  1  DJ-1_PfpI  DJ-1/PfpI family


Domain annotation for each model (and alignments):
>> DJ-1_PfpI  DJ-1/PfpI family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.2   0.0     2e-15   3.5e-11      46     160 ..      75     192 ..      45     197 .. 0.80

  Alignments for each domain:
  == domain 1  score: 43.2 bits;  conditional E-value: 2e-15
                 EEEE-SEEGGGCTCCG-SEEEE--BHHHHHHHHTSHHHHHHHHHHHHTT..-EEEEETTTHHHHHHTTTTTTSEE--SGGGH...HHHHHTTSEE-SS. CS
   DJ-1_PfpI  46 lkvtvdaslddvkaaeyDalvlpGGragperlrenekvvelvkefaekg..klvaaICagpqlLaaagvlkgrrvTsypavk...dklekagakyvdk. 138
                 l+v+++++  d  + + D l++ GG     +++ +e++ +++++ ++kg  k++++ C+g+ +La++g+l+g+r+T ++++    +++ ++  ++  k 
  EEA21364.1  75 LDVVATVTTAD--CPQIDYLLI-GGPL--PTFKLSEEMSTFIRDRVTKGeiKTIFTTCTGAAVLAQTGLLDGKRATVNMGMIdiaRQM-YPAVNWAQKt 167
                 45555555554..667788766.6655..47888899*********9996678**************************998554566.7777777777 PP

                 ...SEEEETTEEEESSGGGHHHHHH CS
   DJ-1_PfpI 139 ...rvvvdgnlvTsrgpgaaiefal 160
                    + v dgn+ T++g+ + +++  
  EEA21364.1 168 dkdNWVIDGNIWTANGACTGMDMFA 192
                 778**************99998755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (225 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       294  (0.016398); expected 358.6 (0.02)
Passed bias filter:                      280  (0.0156172); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 1559.51
//
Query:       EEA21365.1  [L=476]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
      0.053   13.4   0.1       0.19   11.6   0.0    1.7  1  HEPN-like_int  HEPN-like integron domain


Domain annotation for each model (and alignments):
>> HEPN-like_int  HEPN-like integron domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0     1e-05      0.19      40      88 ..     160     206 ..     151     209 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 1e-05
  HEPN-like_int  40 vlapseeslvayvalsrvalsnliigifklsEliEkkdrlltslpiEla 88 
                     + ps+e l  +  l+   l+ +i  i+kl+ +iEk +++  +l  E+a
     EEA21365.1 160 TFIPSNELLDSMLLLNDGPLEPIIASIVKLCKFIEKVHGI--NLQTEMA 206
                    68899999999999999999*******************9..7777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (476 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       435  (0.0242624); expected 358.6 (0.02)
Passed bias filter:                      339  (0.0189079); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.24s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 3287.85
//
Query:       EEA21366.1  [L=396]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.8e-06   26.4   0.0    1.1e-05   25.4   0.0    1.7  1  SpoIIE    Stage II sporulation protein E (SpoIIE)
    7.9e-05   22.4   0.1       0.28   10.8   0.0    2.2  2  PP2C      Protein phosphatase 2C
     0.0011   18.6   0.1     0.0017   18.1   0.1    1.2  1  PP2C_2    Protein phosphatase 2C
  ------ inclusion threshold ------
       0.14   11.7   0.1       0.43   10.1   0.0    1.8  2  Mgm101p   Mitochondrial genome maintenance MGM101


Domain annotation for each model (and alignments):
>> SpoIIE  Stage II sporulation protein E (SpoIIE)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.4   0.0   2.5e-09   1.1e-05      58     166 ..     201     323 ..     135     391 .. 0.75

  Alignments for each domain:
  == domain 1  score: 25.4 bits;  conditional E-value: 2.5e-09
                 T....TTCEEEEEE...EETTTTEEEEEEESSSSEEEEETTS.....TEEEEE--SS--..TTTSSS....T-EEEEEEE--TTEEEEEESCCCCSSSH CS
      SpoIIE  58 e...erfaTavlav...ydpstgkleyanaGhpppllvrpdg.....gtklllastglp..lGilpe....adyetaelelepgdtlllyTDGvtEard 139
                        aTa+l      ++ +  l++ n G+  + ++rp +     + +++ + +  p  lG  +     +d+ ++++ele+gd+++ ++DGvt++  
  EEA21366.1 201 WlgtTTSATALLHCnkqHNTTNPLLYVTNIGDCQITVIRPRDrkvvfRSREQWHWFDCPyqLGTNSAdqprTDAVVNTVELEEGDIVIAVSDGVTDNL- 298
                 2333477777777677788999999***************7755555555555555666999997779999************************999. PP

                 HHHHHCCCHHCHHHHCT.....HCCHH CS
      SpoIIE 140 sdgelfgkerllallasaegesleell 166
                  d+e+  +++ l+ +++ e++++  ll
  EEA21366.1 299 WDHEI--VDNVLESIKKWETRDVGNLL 323
                 66666..66777777766555555554 PP

>> PP2C  Protein phosphatase 2C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.8   0.0   6.2e-05      0.28      37     132 ..     139     243 ..     107     252 .. 0.60
   2 !    9.6   0.1   0.00015      0.65     202     247 ..     282     331 ..     267     338 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 6.2e-05
                 EEEEEEESSSHHHHHHHHHHHHHHHHHHHCHTTH.HHHHHHHHHHHHHHHHHHHH.HHHHCHCCT-EEEEEEEEEETTE........EEEEEESS-EEE CS
        PP2C  37 favfdghggseaakyarehleeilksqksfeele.kleqalrksfladtdeelks.skantepsksGstavvalirgtk........lyvAnvGDSrav 125
                 ++v dg+g  +++ + +  l+  l +     e+e ++    +  + + + ++ +  ++a+t  +   +t+ +al+  +k        lyv+n GD+++ 
  EEA21366.1 139 LGVNDGVGAWQMKPKGHAALWSRLILHFWALECErQVTCTSQPDTIE-FLQNAYEeTIAATRNWLGTTTSATALLHCNKqhnttnplLYVTNIGDCQIT 236
                 56666666666666666666644444444444433222222222222.33333332333334455555555555555555669***************9 PP

                 EEETTEE CS
        PP2C 126 Lcrkgna 132
                 ++r ++ 
  EEA21366.1 237 VIRPRDR 243
                 9987765 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00015
                 -TTEEEEEEE-HHHHTTSHHHHHHHHHHHHHHHHT.....HHHHHHHHHHH CS
        PP2C 202 teedefliLacdGlwdvlsdqeavdlvrdelekkk.....speevaeelvd 247
                 +e  + +i ++dG++d l d e+vd v + ++k++     ++ ++a ++ +
  EEA21366.1 282 EE-GDIVIAVSDGVTDNLWDHEIVDNVLESIKKWEtrdvgNLLTAASAMGQ 331
                 33.4578889************************76655555555555444 PP

>> PP2C_2  Protein phosphatase 2C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.1   3.7e-07    0.0017      27     192 ..     139     311 ..     121     328 .. 0.65

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 3.7e-07
      PP2C_2  27 laVaDGaGS...akrSerG..ariave.avvealaelleseeeeeeallraleaailadvlkeeaeaqdaelkdyatTllaav..vtpde....ivalq 113
                 l V DG+G+   +++++ +  +r++ + ++ e+ +++  ++++++ ++l+++ ++        +a  ++      at+ll +   +  ++    + + +
  EEA21366.1 139 LGVNDGVGAwqmKPKGHAAlwSRLILHfWALECERQVTCTSQPDTIEFLQNAYEETI------AATRNWLGTTTSATALLHCNkqH--NTtnplLYVTN 229
                 368888888444445555455666666444555555554455554444444443333......35556777777777777777541..333455889** PP

      PP2C_2 114 iGDGaivvrd.rdgevqllgepds..geyanqttfltsedaeeelrirrlkledgdalllmTDGlanslrdeerfaelleel 192
                 iGD+ i v++ rd++v   + ++    +   q  + +++++  +  +++++le+gd ++ ++DG++++l d+e ++  le +
  EEA21366.1 230 IGDCQITVIRpRDRKVVFRSREQWhwFDCPYQLGTNSADQPRTDAVVNTVELEEGDIVIAVSDGVTDNLWDHEIVDNVLESI 311
                 ******66552666664444433323677788999999999**************************999888766666655 PP

>> Mgm101p  Mitochondrial genome maintenance MGM101
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   9.5e-05      0.43      55     101 ..     144     190 ..     138     224 .. 0.73
   2 ?   -2.1   0.0      0.52   2.3e+03     122     135 ..     293     306 ..     290     317 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 9.5e-05
     Mgm101p  55 GpggWglaprgetvvtekivtreyaLvvegrlvsearGeqeyfeees 101
                 G g+W ++p+g++++ ++++ + +aL +e ++  +++ ++  f ++ 
  EEA21366.1 144 GVGAWQMKPKGHAALWSRLILHFWALECERQVTCTSQPDTIEFLQNA 190
                 889**************************999999988765554433 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.52
     Mgm101p 122 GiaseLWdPefirk 135
                 G++ +LWd e + +
  EEA21366.1 293 GVTDNLWDHEIVDN 306
                 89999***998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (396 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       477  (0.0266049); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 2753.37
//
Query:       EEA21367.1  [L=450]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (450 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       404  (0.0225333); expected 358.6 (0.02)
Passed bias filter:                      276  (0.0153941); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.24s 00:00:00.73 Elapsed: 00:00:00.41
# Mc/sec: 3300.74
//
Query:       EEA21368.1  [L=400]
Description: F-box domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
     0.0014   18.5   1.5     0.0029   17.5   0.1    2.3  3  F-box-like  F-box-like
     0.0091   15.9   0.6      0.024   14.5   0.0    2.1  2  F-box       F-box domain
  ------ inclusion threshold ------
      0.039   14.4   0.2        7.5    7.1   0.0    3.0  2  LRR_4       Leucine Rich repeats (2 copies)


Domain annotation for each model (and alignments):
>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   0.1   4.9e-07    0.0029       2      30 ..       6      34 ..       5      42 .. 0.92
   2 ?   -2.6   0.0      0.87   5.2e+03      21      36 ..     116     131 ..     104     133 .. 0.66
   3 ?   -3.2   0.0       1.4   8.2e+03      35      43 ..     365     373 ..     364     375 .. 0.75

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 4.9e-07
  F-box-like  2 srLPdEiLlqIFsyLppsdLlrlalVCrr 30
                s LP EiL  I+sy+p   Ll+  +++++
  EEA21368.1  6 SKLPVEILFIILSYVPIPALLSFGATSKS 34
                78************************996 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 0.87
  F-box-like  21 LlrlalVCrrWrrval 36 
                 +++l +++r+ +++++
  EEA21368.1 116 YAALKHTSRKRCSIVS 131
                 5556677777666664 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 1.4
  F-box-like  35 aldtplLWr 43 
                 a  + lLW+
  EEA21368.1 365 AEANKLLWH 373
                 666789998 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.0     4e-06     0.024       3      32 ..       5      34 ..       3      36 .. 0.94
   2 ?   -3.2   0.2       1.4   8.6e+03      20      30 ..     121     131 ..     119     132 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 4e-06
                HHHS-HHHHHHHHHTS-HHHHHHHCTT-HH CS
       F-box  3 lsrLPsevlrhILerLplsdllalrrVSkg 32
                ls LP e+l  IL+++p   ll++  +Sk+
  EEA21368.1  5 LSKLPVEILFIILSYVPIPALLSFGATSKS 34
                89**********************999996 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 1.4
                 HHHHHHHCTT- CS
       F-box  20 lsdllalrrVS 30 
                 ++++ +++ VS
  EEA21368.1 121 HTSRKRCSIVS 131
                 67888999998 PP

>> LRR_4  Leucine Rich repeats (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0     0.014        84       2      30 ..     240     271 ..     239     276 .. 0.88
   2 ?    7.1   0.0    0.0013       7.5      16      36 ..     339     359 ..     334     375 .. 0.79

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.014
                 S--EEE--SS---E-S-..HHH.-TT--EEE- CS
       LRR_4   2 nLevLdLsnNqltdipl..lek.lpnLkeLdL 30 
                 nLe+L L    +t ++l  l k +++Lk+L L
  EEA21368.1 240 NLESLILERAGITPWQLrmLVKrNKSLKVLKL 271
                 99999999999999999998899*******99 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0013
                 -S-HHH-TT--EEE-.-S--- CS
       LRR_4  16 iplleklpnLkeLdLsgNnli 36 
                 ++++ +l++L++L+L ++ +i
  EEA21368.1 339 LDWIHNLKSLESLSLRECRNI 359
                 566778*********666444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (400 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       457  (0.0254894); expected 358.6 (0.02)
Passed bias filter:                      426  (0.0237604); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2706.96
//
Query:       EEA21369.1  [L=320]
Description: ARP2/3 complex 34 kDa subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   4.7e-108  360.4   0.0   5.6e-108  360.2   0.0    1.0  1  P34-Arc   Arp2/3 complex, 34 kD subunit p34-Arc
  ------ inclusion threshold ------
      0.071   12.7   0.1       0.13   11.8   0.1    1.4  1  ARPC4     ARP2/3 complex 20 kDa subunit (ARPC4)


Domain annotation for each model (and alignments):
>> P34-Arc  Arp2/3 complex, 34 kD subunit p34-Arc
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  360.2   0.0  6.2e-112  5.6e-108       1     240 []      52     303 ..      52     303 .. 0.98

  Alignments for each domain:
  == domain 1  score: 360.2 bits;  conditional E-value: 6.2e-112
                 EEEE-TTHHHHHTTTHHHHHHHHSTTTE.E---TTSSEEE---TTS------SHHHHHHHHHTHHHHHTSHHHHHHHTHHHH------........... CS
     P34-Arc   1 vsislkcwkelkkygaeellkreYgkllkaepesgydvsllvdleelpedeeekeelikklsllkrnllaapfekafeeqeelseeke........... 88 
                 +si+lkc++el++yga+e+l+reYg ++ ++pe+gyd+s+++dle+lp+d+e keeli +lsllkrn++aapfe+af+e+++lsee++           
  EEA21369.1  52 ISIALKCFRELVQYGAQEVLEREYGPYI-VNPEPGYDFSVQIDLENLPADAEGKEELIGRLSLLKRNVMAAPFERAFDEFAKLSEEAAkytsesapqgv 149
                 79**************************.*******************************************************887789********* PP

                 HHTTT-EEE--SSS--EEEEE-SSEEEEEEEE--SSSSHHHHHHHHHHHHH-----..------EEEE-SSS--S---S-------..---EEEEEEEE CS
     P34-Arc  89 sekeevaaikYrddEaiyikpskdrvtvifstvFkdetDkvlgkvFLqefvdarkr..aiqsaPqvlfsekepplelrdlkeakkk..envgyvtfvLf 183
                 +e  ev+ai+Yr++Eaiyik+s+drvtvifst+F++etD+++gkvFLqefvdar+r  ++q+aPqvlf++ +pplel++++++k++   + +y+tfvLf
  EEA21369.1 150 KEGGEVMAIHYREEEAIYIKSSHDRVTVIFSTIFREETDRIFGKVFLQEFVDARRRvqSLQNAPQVLFRN-DPPLELQGIPGLKNSgdGKYSYITFVLF 247
                 99******************************************************99************.************97777899******** PP

                 GGGG.-TTTHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSS--- CS
     P34-Arc 184 prhlkteekrentisliqlfRnylhYHiKcsKaylhsrmRarvseflkvLnrAkpee 240
                 prhl t+++r ++is+iq+fR+y+hYHiK+sKay+h+rmR+r+++fl++LnrA+pe+
  EEA21369.1 248 PRHL-TPQRRYDSISHIQTFRDYFHYHIKASKAYIHTRMRKRTADFLQILNRARPEN 303
                 ***8.**************************************************96 PP

>> ARPC4  ARP2/3 complex 20 kDa subunit (ARPC4)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.1   1.5e-05      0.13      51     166 ..     156     294 ..     149     295 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 1.5e-05
                 EEEESSSS-EEEEEEBSSEEEEEEE----SSHHHHHHHHHHHHHGGGTTTSTTB-SS--T......................T-S.EEEEEETTHHHHS CS
       ARPC4  51 lviarsekekvliEssinSvRvSlkikqadelerillkkftrflmkraeafeilRrkpve......................gyd.iSfLitnehvekl 126
                 ++i   e+e ++i ss + v v ++  + +e +ri  k f++ +     + + l  +p                         y  i+f +   h+   
  EEA21369.1 156 MAIHYREEEAIYIKSSHDRVTVIFSTIFREETDRIFGKVFLQEFVDARRRVQSLQNAPQVlfrndpplelqgipglknsgdgKYSyITFVLFPRHLTPQ 254
                 6788899*********************************99998888888888888866788999999************955449************ PP

                 -HHHHHHHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHH CS
       ARPC4 127 gkkklidfiikFveeidkeiselklslnararivaeeflk 166
                  +++ i  i +F      +i+  k  + +r r   + fl+
  EEA21369.1 255 RRYDSISHIQTFRDYFHYHIKASKAYIHTRMRKRTADFLQ 294
                 ********************************99999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (320 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       565  (0.0315132); expected 358.6 (0.02)
Passed bias filter:                      493  (0.0274974); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 2085.98
//
Query:       EEA21370.1  [L=957]
Description: small nucleolar ribonucleoprotein complex subunit Dip2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.2e-55  181.4  25.6    1.2e-06   29.1   0.1   11.9 12  WD40           WD domain, G-beta repeat
    1.4e-21   76.8   0.2    2.8e-21   75.8   0.2    1.5  1  Utp12          Dip2/Utp12 Family
    3.3e-21   75.4   2.7      0.082   13.2   0.0    9.0  9  ANAPC4_WD40    Anaphase-promoting complex subunit 4 WD40 doma
    1.1e-07   31.1   2.8       0.58    9.1   0.0    6.2  6  Ge1_WD40       WD40 region of Ge1, enhancer of mRNA-decapping
    3.3e-05   22.8   3.5       0.22   10.2   0.1    4.5  5  Nucleoporin_N  Nup133 N terminal like
    0.00023   19.9   9.1      0.021   13.5   0.0    5.2  7  Nup160         Nucleoporin Nup120/160
    0.00028   20.3   0.0        2.5    7.3   0.0    3.8  4  WD40_like      WD40-like domain
  ------ inclusion threshold ------
      0.016   15.1   1.7        8.1    6.3   0.0    4.7  6  eIF2A          Eukaryotic translation initiation factor eIF2A
      0.021   13.2   0.0       0.93    7.7   0.0    2.5  3  Frtz           WD repeat-containing and planar cell polarity 
      0.076   12.7   0.2        2.7    7.6   0.0    3.3  4  Hira           TUP1-like enhancer of split


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.8   0.2   9.4e-05      0.17      13      38 .]      75     101 ..      61     101 .. 0.79
   2 !   26.1   0.1   6.1e-09   1.1e-05       4      38 .]     108     143 ..     105     143 .. 0.94
   3 !   16.3   0.0   7.3e-06     0.013       4      38 .]     150     199 ..     147     199 .. 0.86
   4 !    9.4   0.4    0.0011         2       9      38 .]     208     242 ..     201     242 .. 0.72
   5 ?   -1.3   0.0       2.7   4.9e+03      14      37 ..     279     302 ..     271     303 .. 0.82
   6 !   24.6   0.0   1.8e-08   3.3e-05       7      38 .]     416     447 ..     410     447 .. 0.94
   7 ?    0.2   0.0      0.91   1.6e+03      15      38 .]     462     487 ..     451     487 .. 0.71
   8 !   29.1   0.1   6.6e-10   1.2e-06       3      38 .]     493     529 ..     491     529 .. 0.93
   9 !   10.9   0.0   0.00038      0.68       5      37 ..     553     585 ..     549     585 .. 0.85
  10 !   17.2   0.0   3.8e-06    0.0067       6      37 ..     595     627 ..     590     627 .. 0.89
  11 !   12.2   0.0   0.00015      0.26       2      38 .]     633     675 ..     632     675 .. 0.85
  12 !   29.1   0.1   6.6e-10   1.2e-06       3      38 .]     681     717 ..     679     717 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 9.4e-05
                 EEEEE.EETTSSEEEEEETTSEEEEEE CS
        WD40  13 vtsla.fspdgawlasGsdDgtvriWd 38 
                 vt++    +d + +a G dDg++r+Wd
  EEA21370.1  75 VTAITqSKSDEDIFAVGYDDGSIRLWD 101
                 5666555567777899**********9 PP

  == domain 2  score: 26.1 bits;  conditional E-value: 6.1e-09
                 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 + ++ GH + +t laf+++g  lasGs+D  + +Wd
  EEA21370.1 108 IISFNGHrNAITQLAFDQSGVRLASGSKDTDIIVWD 143
                 6789***999*************************9 PP

  == domain 3  score: 16.3 bits;  conditional E-value: 7.3e-06
                 EEEEESS.SSEEEEE..............EETTSSEEEEEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtsla..............fspdgawlasGsdDgtvriWd 38 
                 l++l+GH + vtsl                s  g +l+s ++D  ++iWd
  EEA21370.1 150 LYKLRGHtDQVTSLNflsptdeanagltdPSETGGFLLSTGKDSLIKIWD 199
                 6789***666****9988888888888888888888999999*******9 PP

  == domain 4  score: 9.4 bits;  conditional E-value: 0.0011
                 SS..SS...EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   9 GH..ss...vtslafspdgawlasGsdDgtvriWd 38 
                 +H  +s    +sl  spd++  ++G+ Dg +++W+
  EEA21370.1 208 THvaQSngeCWSLGLSPDQTGCITGGNDGELKVWS 242
                 44331234566777999999999***********5 PP

  == domain 5  score: -1.3 bits;  conditional E-value: 2.7
                 EEEEEETTSSEEEEE..ETTSEEEEE CS
        WD40  14 tslafspdgawlasG..sdDgtvriW 37 
                 t++ f+p  +++  G  +  + v iW
  EEA21370.1 279 TGITFHPRADYI--GmhGAEKAVEIW 302
                 788999999997..855469999999 PP

  == domain 6  score: 24.6 bits;  conditional E-value: 1.8e-08
                 EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 l GH ++++sla s+d ++las+s +gt++iW+
  EEA21370.1 416 LPGHrTDIRSLALSSDDRMLASAS-NGTLKIWN 447
                 78***99*****************.*******8 PP

  == domain 7  score: 0.2 bits;  conditional E-value: 0.91
                 EEE..EETTSSEEEEEETTSEEEEEE CS
        WD40  15 sla..fspdgawlasGsdDgtvriWd 38 
                 sl+  f p  + +++G ++g + ++d
  EEA21370.1 462 SLCssFLPGDKIVVTGNKNGELEVFD 487
                 444559999999****9999999887 PP

  == domain 8  score: 29.1 bits;  conditional E-value: 6.6e-10
                 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +l t+++H ++v+ l+++pdg+ +++Gs D+tv++Wd
  EEA21370.1 493 LLDTIKAHeGPVWTLQVHPDGKSMVTGSADKTVKFWD 529
                 577899**999*************************9 PP

  == domain 9  score: 10.9 bits;  conditional E-value: 0.00038
                 EEEESSSSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   5 rtltGHssvtslafspdgawlasGsdDgtvriW 37 
                 rtl+  ++v s++fspd ++la +  D+tv+++
  EEA21370.1 553 RTLKVSDDVLSVRFSPDEKLLAVALLDNTVKVF 585
                 566666679*************9978*****95 PP

  == domain 10  score: 17.2 bits;  conditional E-value: 3.8e-06
                 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   6 tltGH.ssvtslafspdgawlasGsdDgtvriW 37 
                  l GH  +v  ++ s d+++++++s D++vr+W
  EEA21370.1 595 NLYGHkLPVLNMDISYDSKMIVTCSADKNVRLW 627
                 5779*777************************* PP

  == domain 11  score: 12.2 bits;  conditional E-value: 0.00015
                 EEEEEEESS.SSEEEEEEETTSSE.....EEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgaw.....lasGsdDgtvriWd 38 
                 +c r + +H +s+ ++af p+++      ++s+s+D+ ++ Wd
  EEA21370.1 633 DCHRAFFAHqDSIMAVAFMPNNNEgnghnFFSASKDRVIKYWD 675
                 57777889*888*****888888888888999**********9 PP

  == domain 12  score: 29.1 bits;  conditional E-value: 6.6e-10
                 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 ++++l+GH + +++l  s++g +l+s+s D+++r+Wd
  EEA21370.1 681 QIQKLEGHhGEIWALTMSHSGEFLVSASHDKSIRVWD 717
                 67899***777**************9999*******9 PP

>> Utp12  Dip2/Utp12 Family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.8   0.2   1.6e-24   2.8e-21       2     105 ..     819     919 ..     818     921 .. 0.96

  Alignments for each domain:
  == domain 1  score: 75.8 bits;  conditional E-value: 1.6e-24
                 HHHHHH.HHHSS-TTTHHHHHHCS-CTCHHHHHHHHHHHH.HTTTTHHHHHHHHHHHHHHHHHHHHHSH.HHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
       Utp12   2 deelleevlekippsdirltvlrLpssyvlkLLeflaerlaeksphlelllrwlkallrvHgsylvaspsdlvpaLrslqkslrerlktlskllglnlg 100
                 +++ll+ +++kip++++++++l+Lp+s ++ L++fl+ ++ ++++ + l++r+l+++l++H++++v+s+ +++p+L++++++lre+l+++++ +g+nl+
  EEA21370.1 819 ERHLLN-IVQKIPAASLQDALLVLPFSKLEALFTFLEIWA-SRQWEIPLTCRILFFMLKTHHRQIVSSR-FMRPMLDRIRSTLREVLAKQKDEMGFNLA 914
                 567788.*******************************99.****************************.7**************************** PP

                 HHHHH CS
       Utp12 101 rLdyl 105
                 +L ++
  EEA21370.1 915 ALHFI 919
                 **997 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.8   0.0   6.3e-05      0.11      38      80 ..      72     115 ..      44     117 .. 0.77
   2 !    8.7   0.0    0.0012       2.1      37      89 ..     114     165 ..     110     167 .. 0.91
   3 ?    0.1   0.0      0.58     1e+03      50      81 ..     183     214 ..     180     254 .. 0.75
   4 ?   -1.8   0.0       2.3   4.1e+03      38      79 ..     275     316 ..     268     323 .. 0.71
   5 !   13.2   0.0   4.6e-05     0.082      30      81 ..     412     462 ..     374     469 .. 0.80
   6 !    7.9   0.0    0.0021       3.8       9      66 ..     473     529 ..     465     537 .. 0.80
   7 !   13.1   0.0   4.9e-05     0.088      37      73 ..     557     593 ..     546     609 .. 0.83
   8 !   12.5   0.0   7.9e-05      0.14       2      89 ..     565     650 ..     564     653 .. 0.86
   9 !    7.3   0.0    0.0031       5.6      35      73 ..     686     724 ..     665     737 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 6.3e-05
  ANAPC4_WD40  38 dsevrsLa.WkpdgklLavaysdgevrlldaesgkvvhslsvks 80 
                  + +v+++   k d+ ++av+y+dg++rl d+   +v+ s++ ++
   EEA21370.1  72 NAQVTAITqSKSDEDIFAVGYDDGSIRLWDSRMNNVIISFNGHR 115
                  566666641478999*********************99998665 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.0012
  ANAPC4_WD40  37 edsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                  + + +++La+ ++g  La + +d+ + + d  s+  + +l+ ++++ vt+l++
   EEA21370.1 114 HRNAITQLAFDQSGVRLASGSKDTDIIVWDLISEVGLYKLRGHTDQ-VTSLNF 165
                  6789*******************************9*999999995.999987 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.58
  ANAPC4_WD40  50 gklLavaysdgevrlldaesgkvvhslsvkse 81 
                  g +L    +d+ +++ d +s +++++  ++s+
   EEA21370.1 183 GGFLLSTGKDSLIKIWDLSSRHCIETHVAQSN 214
                  67788888888888888888888877666554 PP

  == domain 4  score: -1.8 bits;  conditional E-value: 2.3
  ANAPC4_WD40  38 dsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvk 79 
                  + + +++ ++p    + +  ++ +v++  + s++ v+++ + 
   EEA21370.1 275 KDRTTGITFHPRADYIGMHGAEKAVEIWRIRSATEVQKSIAR 316
                  555677777777777777777788888887777777766555 PP

  == domain 5  score: 13.2 bits;  conditional E-value: 4.6e-05
  ANAPC4_WD40  30 wtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvkse 81 
                  + ++ +++   +rsLa + d+++La a s+g++++ ++ ++ ++++l+++ +
   EEA21370.1 412 FAVDLPGHRTDIRSLALSSDDRMLASA-SNGTLKIWNVRTQSCLRTLDCGYS 462
                  55566788999*************976.89*****************99876 PP

  == domain 6  score: 7.9 bits;  conditional E-value: 0.0021
  ANAPC4_WD40   9 LiAlatedgellvfRlngqrvwtleedkedsevrsLaWkpdgklLavaysdgevrlld 66 
                  ++  ++++gel+vf +    + ++  +++++ v  L+ +pdgk ++ + +d +v++ d
   EEA21370.1 473 IVVTGNKNGELEVFDIASSTLLDT-IKAHEGPVWTLQVHPDGKSMVTGSADKTVKFWD 529
                  556677788888888888888877.688899999999999999999999999999877 PP

  == domain 7  score: 13.1 bits;  conditional E-value: 4.9e-05
  ANAPC4_WD40  37 edsevrsLaWkpdgklLavaysdgevrlldaesgkvv 73 
                   +  v s++++pd+klLava  d++v+++ + + k+ 
   EEA21370.1 557 VSDDVLSVRFSPDEKLLAVALLDNTVKVFFVDTLKLF 593
                  566899*********************9988887765 PP

  == domain 8  score: 12.5 bits;  conditional E-value: 7.9e-05
  ANAPC4_WD40   2 swcptmDLiAlatedgellvfRlngqrvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                  +++p   L+A+a  d+ + vf ++  +++     +++  v ++  + d k+++   +d +vrl     g++ +++ +++++ ++ + +
   EEA21370.1 565 RFSPDEKLLAVALLDNTVKVFFVDTLKLFLN-LYGHKLPVLNMDISYDSKMIVTCSADKNVRLWGLDFGDCHRAFFAHQDS-IMAVAF 650
                  6899999999999999999999999999987.6899999999999999999999999999999999999999999999885.877766 PP

  == domain 9  score: 7.3 bits;  conditional E-value: 0.0031
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdgevrlldaesgkvv 73 
                  +++ +e+ +L  +++g++L+ a +d ++r+ d  ++++ 
   EEA21370.1 686 EGHHGEIWALTMSHSGEFLVSASHDKSIRVWDQTDEQIF 724
                  678999**************************9998875 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.7   0.0    0.0033         6     165     282 ..      92     208 ..      65     218 .. 0.71
   2 ?    0.5   0.0      0.13   2.3e+02     194     217 ..     221     244 ..     210     256 .. 0.80
   3 !    6.6   0.2    0.0018       3.2     145     218 ..     377     450 ..     369     499 .. 0.73
   4 !    5.7   0.0    0.0035       6.3     183     221 ..     496     535 ..     472     551 .. 0.75
   5 !    9.1   0.0   0.00032      0.58     146     216 ..     516     587 ..     508     593 .. 0.74
   6 ?    0.6   0.0      0.12   2.2e+02     183     222 ..     684     729 ..     662     735 .. 0.79

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0033
    Ge1_WD40 165 skygsgelsveeieegllkieehs.liveaafspdGtalatasedGevkffqvyledeeeprCLheWkPhdGkslssllfl...dnhkee.sd.eqfWr 257
                  + gs+ l  ++++++++ ++ h   i++ af   G  la  s+d  +  + +      ++  L++ + h   +++sl fl   d+ +   +d ++   
  EEA21370.1  92 YDDGSIRLWDSRMNNVIISFNGHRnAITQLAFDQSGVRLASGSKDTDIIVWDLI-----SEVGLYKLRGHTD-QVTSLNFLsptDEANAGlTDpSETGG 184
                 455667777889999*******9769********************99888765.....4567899999975.57778887232333332334144555 PP

    Ge1_WD40 258 faitgadnnselklWscelWtClqt 282
                 f++ +  ++s +k+W  ++ +C+ t
  EEA21370.1 185 FLLST-GKDSLIKIWDLSSRHCIET 208
                 65544.5667899999999999887 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.13
    Ge1_WD40 194 afspdGtalatasedGevkffqvy 217
                  +spd t   t  +dGe+k + + 
  EEA21370.1 221 GLSPDQTGCITGGNDGELKVWSID 244
                 589999999999999999999875 PP

  == domain 3  score: 6.6 bits;  conditional E-value: 0.0018
    Ge1_WD40 145 kllvltrgdkaeiwsvdmiaskygsgelsveeieegllkieehs.liveaafspdGtalatasedGevkffqvyl 218
                 ++l  t ++++e + v +  +k ++   +ve  ++  + +  h   i + a+s+d   la as +G++k + v  
  EEA21370.1 377 QILTATTNNEIETYRVVAAGKKKTKDTEEVEYSRNFAVDLPGHRtDIRSLALSSDDRMLASAS-NGTLKIWNVRT 450
                 556666667777777777766666666666666777777777743677777777777777765.47777776643 PP

  == domain 4  score: 5.7 bits;  conditional E-value: 0.0035
    Ge1_WD40 183 kieehs.liveaafspdGtalatasedGevkffqvylede 221
                  i+ h   + +  + pdG ++ t s+d +vkf+   +++e
  EEA21370.1 496 TIKAHEgPVWTLQVHPDGKSMVTGSADKTVKFWDFKVVQE 535
                 455564467788899*****************98777655 PP

  == domain 5  score: 9.1 bits;  conditional E-value: 0.00032
    Ge1_WD40 146 llvltrgdkaeiwsvdmiaskygsgelsveeieegllkieehs.liveaafspdGtalatasedGevkffqv 216
                 ++  +  + ++ w++++++++   ++ ++ +++ +  +  + s  + +  fspd   la+a  d +vk f v
  EEA21370.1 516 MVTGSADKTVKFWDFKVVQEEIPGTKRTTPKLKLVHSRTLKVSdDVLSVRFSPDEKLLAVALLDNTVKVFFV 587
                 45555566789999999999987666666666655544444443789999******************9976 PP

  == domain 6  score: 0.6 bits;  conditional E-value: 0.12
    Ge1_WD40 183 kieehs.liveaafspdGtalatasedGevkff.....qvyledee 222
                 k+e h  +i   ++s  G  l  as+d  ++ +     q++le+e+
  EEA21370.1 684 KLEGHHgEIWALTMSHSGEFLVSASHDKSIRVWdqtdeQIFLEEER 729
                 556554499999*******************996666667777665 PP

>> Nucleoporin_N  Nup133 N terminal like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0      0.79   1.4e+03     137     159 ..      75     100 ..      72     101 .. 0.87
   2 !    6.2   0.1     0.002       3.6     189     245 ..     106     159 ..      93     180 .. 0.83
   3 ?   -0.7   0.0      0.26   4.7e+02     216     260 ..     378     425 ..     368     453 .. 0.58
   4 ?    2.9   0.0      0.02        36     196     268 ..     494     561 ..     429     590 .. 0.72
   5 !   10.2   0.1   0.00012      0.22     192     260 ..     680     748 ..     603     761 .. 0.75

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.79
                    EEEEEEETTTC-EEEEETTS...SEE CS
  Nucleoporin_N 137 vtqvinseptgriflagstg...rly 159
                    vt +++s+++ +if++g ++   rl+
     EEA21370.1  75 VTAITQSKSDEDIFAVGYDDgsiRLW 100
                    89999************999877777 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.002
                    --SSS--G----GG-EEEEEEECCTCEEEEEETTSEEEEEEEETTCEE-EEEEEEEH CS
  Nucleoporin_N 189 silpgvlsgasereeivqlridssrrilytlsskgvirvydlsasngesslksdidi 245
                    +++ ++++    r++i+ql+ d+s  +l + s +  i v+dl ++ g  +l++++d+
     EEA21370.1 106 NVIISFNG---HRNAITQLAFDQSGVRLASGSKDTDIIVWDLISEVGLYKLRGHTDQ 159
                    78888888...9******************************988877777766665 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 0.26
                    EEEEETTSEEEEEEEETTCE.E-EEEEEEEHHHHHHHH...HHSCHTT CS
  Nucleoporin_N 216 lytlsskgvirvydlsasng.esslksdidirqillea..iteslias 260
                    + t+++  +i++y++ a+++ + + +++++ +++++    ++ ++i+s
     EEA21370.1 378 ILTATTNNEIETYRVVAAGKkKTKDTEEVEYSRNFAVDlpGHRTDIRS 425
                    678999999999999955543333344444444444444444444444 PP

  == domain 4  score: 2.9 bits;  conditional E-value: 0.02
                    G..----GG-EEEEEEECCTCEEEEEETTSEEEEEEEETTCEE-EEEEEEEHHHHHHHH...HHSCHTTTCGCTTT- CS
  Nucleoporin_N 196 s..gasereeivqlridssrrilytlsskgvirvydlsasngesslksdidirqillea..itesliasaplasksl 268
                       ++  + +++ l +++  +  +t s++++++++d+   ++e   +++++++ +l+++  +         ++s ++
     EEA21370.1 494 LdtIKAHEGPVWTLQVHPDGKSMVTGSADKTVKFWDFKVVQEEIPGTKRTTPKLKLVHSrtL---------KVSDDV 561
                    14567788999999999999999999999999999999998888888888888888887332.........333333 PP

  == domain 5  score: 10.2 bits;  conditional E-value: 0.00012
                    SS--G----GG-EEEEEEECCTCEEEEEETTSEEEEEEEETTCE.E-EEEEEEEHHHHHHHH.HHSCHTT CS
  Nucleoporin_N 192 pgvlsgasereeivqlridssrrilytlsskgvirvydlsasng.esslksdidirqilleaiteslias 260
                    +++ +    + ei++l+ ++s + l+++s ++ irv+d + +++   + ++++++++ + +++t+sl ++
     EEA21370.1 680 EQIQKLEGHHGEIWALTMSHSGEFLVSASHDKSIRVWDQT-DEQiFLEEEREKELEELYENTLTTSLEDE 748
                    44445666899***************************66.65535666666666666666666666655 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0      0.51   9.1e+02     223     255 ..      76     110 ..      67     137 .. 0.74
   2 ?   -1.1   0.0      0.31   5.6e+02     233     255 ..     186     208 ..     177     232 .. 0.80
   3 ?   -3.0   0.0       1.1     2e+03     239     250 ..     235     246 ..     221     251 .. 0.86
   4 !   13.5   0.0   1.2e-05     0.021     234     259 ..     436     460 ..     420     495 .. 0.84
   5 ?   -1.0   0.0      0.28   5.1e+02     221     252 ..     557     592 ..     539     597 .. 0.73
   6 ?    2.6   0.0     0.024        43     225     252 ..     608     634 ..     601     643 .. 0.81
   7 !    4.0   0.1    0.0086        15     229     277 ..     700     748 ..     692     768 .. 0.74

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.51
                 T.......TTTEEEEEETT-EEEEEETTTTEEEEE CS
      Nup160 223 vavvei..gqtylfalsrdgkLrvWnlltgkclat 255
                 +a++++  ++++ ++ + dg +r+W+ + + ++ +
  EEA21370.1  76 TAITQSksDEDIFAVGYDDGSIRLWDSRMNNVIIS 110
                 345555658888888899*******9876666555 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.31
                 EEEEETT-EEEEEETTTTEEEEE CS
      Nup160 233 lfalsrdgkLrvWnlltgkclat 255
                 l++   d  +++W+l++  c++t
  EEA21370.1 186 LLSTGKDSLIKIWDLSSRHCIET 208
                 5555668889**********998 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 1.1
                 T-EEEEEETTTT CS
      Nup160 239 dgkLrvWnlltg 250
                 dg+L+vW+++ +
  EEA21370.1 235 DGELKVWSIDEQ 246
                 99******9865 PP

  == domain 4  score: 13.5 bits;  conditional E-value: 1.2e-05
                 EEEETT-EEEEEETTTTEEEEEEE-- CS
      Nup160 234 falsrdgkLrvWnlltgkclatidll 259
                 ++  ++g+L++Wn++t++cl+t d+ 
  EEA21370.1 436 AS-ASNGTLKIWNVRTQSCLRTLDCG 460
                 33.469****************9985 PP

  == domain 5  score: -1.0 bits;  conditional E-value: 0.28
                 EET.........TTTEEEEEETT-EEEEEETTTTEE CS
      Nup160 221 vavavvei....gqtylfalsrdgkLrvWnlltgkc 252
                 v+ +v ++    ++++l+++ +d++++v  ++t+k+
  EEA21370.1 557 VSDDVLSVrfspDEKLLAVALLDNTVKVFFVDTLKL 592
                 333333333345999*************99999886 PP

  == domain 6  score: 2.6 bits;  conditional E-value: 0.024
                 ....TTTEEEEEETT-EEEEEETTTTEE CS
      Nup160 225 vveigqtylfalsrdgkLrvWnlltgkc 252
                 ++  +++++++ s d+++r+W l+ g c
  EEA21370.1 608 ISY-DSKMIVTCSADKNVRLWGLDFGDC 634
                 333.99***************9986666 PP

  == domain 7  score: 4.0 bits;  conditional E-value: 0.0086
                 TTTEEEEEETT-EEEEEETTTTEEEEEEE--.-SSSTTS--SSEESEEE CS
      Nup160 229 gqtylfalsrdgkLrvWnlltgkclatidllrdeeaqdessskstldpa 277
                    +l+++s d+ +rvW+ ++ ++    +  +++e+  e++  ++l+++
  EEA21370.1 700 SGEFLVSASHDKSIRVWDQTDEQIFLEEEREKELEELYENTLTTSLEDE 748
                 5679**************9999999887777555555555555555554 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.7   0.0    0.0022         4      84     156 ..      77     153 ..      61     169 .. 0.79
   2 ?   -2.2   0.0       1.1     2e+03       2      37 ..     216     251 ..     215     255 .. 0.83
   3 ?    1.0   0.0      0.12   2.1e+02     239     295 ..     423     478 ..     407     525 .. 0.61
   4 !    7.3   0.0    0.0014       2.5       3      54 ..     603     654 ..     601     686 .. 0.92

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0022
   WD40_like  84 distvkviddklliGtnkGsiyvfskdlqleev.llgqsseIkeikiennki..ysLs.esafivfdlfsqnieyki 156
                 +i+  k ++d +++G + Gsi +++  ++++++ + g+   I ++  +++ +   s s ++  iv+dl+s+  +yk+
  EEA21370.1  77 AITQSKSDEDIFAVGYDDGSIRLWDSRMNNVIIsFNGHRNAITQLAFDQSGVrlASGSkDTDIIVWDLISEVGLYKL 153
                 6778889999*****************99988736789999****99987541144442567899999998777776 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.1
   WD40_like   2 eiYsidiskkgslilyGgkddkctvlkleslesvsi 37 
                 e +s+ +s++ +  + Gg+d +++v +++ + +  i
  EEA21370.1 216 ECWSLGLSPDQTGCITGGNDGELKVWSIDEQAMQEI 251
                 6678899999999999********999998876655 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 0.12
   WD40_like 239 iskikkisefvvafsTlcgkvgigDiRdketfkllesgvGviydmkfenntiyvgGe 295
                 i+ +   s+ ++  s  +g++ i  +R ++ ++ l++g     ++ +  ++i+v+G+
  EEA21370.1 423 IRSLALSSDDRMLASASNGTLKIWNVRTQSCLRTLDCGYSLCSSF-LPGDKIVVTGN 478
                 445555555555556666666666666666666666665544444.33344444443 PP

  == domain 4  score: 7.3 bits;  conditional E-value: 0.0014
   WD40_like   3 iYsidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvkllddd 54 
                 + ++dis ++++i+  + d+++++  l+ ++    +   +dS++ v ++ ++
  EEA21370.1 603 VLNMDISYDSKMIVTCSADKNVRLWGLDFGDCHRAFFAHQDSIMAVAFMPNN 654
                 7799********************************************9887 PP

>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.14   2.5e+02      70     113 ..      83     125 ..      70     161 .. 0.73
   2 ?   -3.2   0.0       3.7   6.7e+03      56      90 ..     356     392 ..     347     412 .. 0.61
   3 ?    3.1   0.0     0.043        78     124     160 ..     440     476 ..     424     478 .. 0.89
   4 ?    6.3   0.0    0.0045       8.1     108     163 ..     467     521 ..     438     533 .. 0.69
   5 ?    0.5   0.0      0.26   4.6e+02     105     164 ..     563     621 ..     543     627 .. 0.75
   6 ?   -3.7   0.0       5.1   9.1e+03     128     168 ..     672     714 ..     671     717 .. 0.67

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.14
                 TSS-EEEEESSSSCEEEEEECSCEEEEEEEEES--EEEE-TTSS CS
       eIF2A  70 kskefaviyGkmpakvslfdlkvkviskleeqkrNtiffspkgk 113
                 + ++ +   G+ + ++ l+d++++ +    + +rN+i   ++++
  EEA21370.1  83 SDED-IFAVGYDDGSIRLWDSRMNNVIISFNGHRNAITQLAFDQ 125
                 3333.334599999********9988888889999987655554 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 3.7
                 EESSS.EEEEEE-TT..SS-EEEEESSSSCEEEEEEC CS
       eIF2A  56 lkkegpihdvaWspk..skefaviyGkmpakvslfdl 90 
                 ++++g+ + +aW ++  s ++ ++    +++++ + +
  EEA21370.1 356 VRTTGKLKSFAWIKTkaSGDLQILTATTNNEIETYRV 392
                 5666777777775431144566666666666666655 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.043
                 S-EEEEEETTTTEEEEEEE-TT--EEEE-TTSSEEEE CS
       eIF2A 124 aGeleiwdvkkkkkiakaeaanatlvewspdgryvlT 160
                 +G+l+iw+v + +++ ++++  +    + p ++ v+T
  EEA21370.1 440 NGTLKIWNVRTQSCLRTLDCGYSLCSSFLPGDKIVVT 476
                 7999******************************999 PP

  == domain 4  score: 6.3 bits;  conditional E-value: 0.0045
                 E-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE-TT--..EEEE-TTSSEEEEEE- CS
       eIF2A 108 fspkgklvllaGfgnlaGeleiwdvkkkkkiakaeaanat..lvewspdgryvlTatt 163
                 f p +k+v++   gn +Gele++d  + + + +++a +    +++ +pdg+ ++T + 
  EEA21370.1 467 FLPGDKIVVT---GNKNGELEVFDIASSTLLDTIKAHEGPvwTLQVHPDGKSMVTGSA 521
                 4555555554...577899999999988888888877754115677888888888764 PP

  == domain 5  score: 0.5 bits;  conditional E-value: 0.26
                 EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE-TT--EEEE-TTSSEEEEEE-T CS
       eIF2A 105 tiffspkgklvllaGfgnlaGeleiwdvkkkkkiakaeaanatlvewspdgryvlTatta 164
                 ++ fsp +kl+++a + n+  ++ ++d+ k+      ++     ++ s+d+++++T++  
  EEA21370.1 563 SVRFSPDEKLLAVALLDNT-VKVFFVDTLKLFLNLYGHKLPVLNMDISYDSKMIVTCSAD 621
                 5889************999.4555555554444444455566678999999999998875 PP

  == domain 6  score: -3.7 bits;  conditional E-value: 5.1
                 EEEETTTTEEEEEEE-TT-..-EEEE-TTSSEEEEEE-TTT-S CS
       eIF2A 128 eiwdvkkkkkiakaeaana..tlvewspdgryvlTattaprlr 168
                 + wd +k+++i+k+e  +     +  s +g++++ a+   ++r
  EEA21370.1 672 KYWDGDKFEQIQKLEGHHGeiWALTMSHSGEFLVSASHDKSIR 714
                 5688899999998875544004566778888888887665555 PP

>> Frtz  WD repeat-containing and planar cell polarity effector protein Fritz
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.0     0.022        40     197     291 ..      51     147 ..      26     157 .. 0.70
   2 ?    7.7   0.0   0.00052      0.93     263     338 ..     424     498 ..     397     512 .. 0.72
   3 ?   -3.2   0.0       1.1   1.9e+03     245     286 ..     544     585 ..     540     629 .. 0.65

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.022
        Frtz 197 evlsyvrteldplsvdfslkqeyqvftveqkvskkkevsa..dsciyelvknklqrvavtsiPlraqvislafnpdedkLllGceDssviLydeerk 291
                 evl++     ++l        + qv ++ q+ s ++  ++  d  +  l  ++++ v +     r  +  laf+++  +L  G++D+ +i++d   +
  EEA21370.1  51 EVLCWDVKKGELLGRWRDADCNAQVTAITQSKSDEDIFAVgyDDGSIRLWDSRMNNVIISFNGHRNAITQLAFDQSGVRLASGSKDTDIIVWDLISE 147
                 6666666666666666666666677777777665553332236677777777777777777777777777888888888888888888888776655 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.00052
        Frtz 263 islafnpdedkLllGceDssviLydeerkitklvkaevvPsli.swhpdsaillvasergelqifDlaLspiriqll 338
                  sla ++ +d++l  + ++++ +++  ++   l   +   sl+ s+ p + i++ ++++gel +fD+a s++   + 
  EEA21370.1 424 RSLALSS-DDRMLASASNGTLKIWNVRTQSC-LRTLDCGYSLCsSFLPGDKIVVTGNKNGELEVFDIASSTLLDTIK 498
                 5555554.45666666677777776655544.3445555555514668999*****************999876655 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 1.1
        Frtz 245 knklqrvavtsiPlraqvislafnpdedkLllGceDssviLy 286
                 + kl+ v   ++ +  +v s+ f+pde  L +   D++v ++
  EEA21370.1 544 TPKLKLVHSRTLKVSDDVLSVRFSPDEKLLAVALLDNTVKVF 585
                 567778888888888899999999999999999999988554 PP

>> Hira  TUP1-like enhancer of split
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0      0.78   1.4e+03      27      45 ..      46      64 ..      44     128 .. 0.75
   2 ?   -3.0   0.0       2.8     5e+03      29      42 ..     234     247 ..     223     250 .. 0.81
   3 ?    7.6   0.0    0.0015       2.7      19      44 ..     429     454 ..     421     471 .. 0.86
   4 ?   -0.2   0.0      0.39     7e+02      17      88 ..     697     770 ..     692     774 .. 0.69

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.78
        Hira 27 vtsvgllyvWnvkkkkvll 45
                v ++ ++ +W+vkk ++l 
  EEA21370.1 46 VGANEEVLCWDVKKGELLG 64
                66788999****9998865 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 2.8
        Hira  29 svgllyvWnvkkkk 42 
                 ++g+l vW +++++
  EEA21370.1 234 NDGELKVWSIDEQA 247
                 589*******9886 PP

  == domain 3  score: 7.6 bits;  conditional E-value: 0.0015
        Hira  19 ssgsyLlavtsvgllyvWnvkkkkvl 44 
                 ss++ +la  s+g+l +Wnv+++++l
  EEA21370.1 429 SSDDRMLASASNGTLKIWNVRTQSCL 454
                 4568999*****************97 PP

  == domain 4  score: -0.2 bits;  conditional E-value: 0.39
        Hira  17 LessgsyLlavtsvgllyvWnvkkkkvllp...pvslapllssssrssekeltrapavtsasltsnGvpivtlsn 88 
                 ++ sg++L+  + + ++ vW+   +++ l+   +++l++l +++ ++s +  +++ + +  ++ +n + +vtl  
  EEA21370.1 697 MSHSGEFLVSASHDKSIRVWDQTDEQIFLEeerEKELEELYENTLTTSLE-DEENGEEKAEAVDANKQTVVTLMA 770
                 55677999999999999****99999999633355677777776666654.444444455566677777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (957 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       800  (0.0446204); expected 358.6 (0.02)
Passed bias filter:                      545  (0.0303977); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.88u 0.34s 00:00:01.22 Elapsed: 00:00:00.50
# Mc/sec: 5762.71
//
Query:       EEA21371.1  [L=441]
Description: glycosyl hydrolase family 43 protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.4e-15   57.4   2.7    1.4e-14   54.1   2.5    2.1  1  Glyco_hydro_43  Glycosyl hydrolases family 43


Domain annotation for each model (and alignments):
>> Glyco_hydro_43  Glycosyl hydrolases family 43
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.1   2.5   7.6e-19   1.4e-14      15     232 ..      48     246 ..      42     274 .. 0.83

  Alignments for each domain:
  == domain 1  score: 54.1 bits;  conditional E-value: 7.6e-19
                     EEEETTCEEEEE...EEBTEESEEEEEEESSSSSCEEEEECEESTTTCSTTTEECTEEEEEE..EETTEEEEEEEEEETTCCCSEEEEEEESSTT CS
  Glyco_hydro_43  15 ilrvgedyYlvt...stfewfpglrifhSkdLvnWkqvgrvlerrsqlsmkgknasWAPeis..khdgkyylyytatkkgeakqgifvvtadspe 104
                     ++ v+++yYl+    ++ ++f+ +++++S+dLv+W+ vg+ l+ +s+ ++        P++    +  ky ly+  ++ + ++ +++v+t ds+ 
      EEA21371.1  48 VIEVDGTYYLIGedkTNGTYFRHVNCYSSTDLVQWNYVGPLLTVTSSGDLGPGRIVERPKVIynSRTKKYVLYMHIDSSSYGEAKVGVATGDSVC 142
                     789999****96222566789*************************9999888887889998335789*******8889999999********** PP

                     S--EECEESSCSTSSECEEEEEEETTSEEEEEEEEEHCCCSEEEEEEEEEETTTTEEEEEEEEEEECGCCTCTTBBEEEEEEEEETTEEEEEEEE CS
  Glyco_hydro_43 105 GpwsdpiklktsgssgiDpslfedddGkkYlvwgqwdkreghseiylaeldddtlklkgektklikagtelkglkvtEGPhlykrdgyyYLlaae 199
                     G+++ +++    g ++ D +lf+dddG                 + +  l+dd+l +++++  ++++          E+P+++k +gyy+++a+ 
      EEA21371.1 143 GTYKYLGSWQPLGYQSRDIGLFQDDDGANG--------------LRIDSLTDDYLNVSAPV--HLFSDM--------EAPAMVKLNGYYFMFASH 213
                     *********766*************98644..............55666**********99..788777........9****************7 PP

                     STSSTTEEEEEEEESSTTSGGEEECTCCSEE.T CS
  Glyco_hydro_43 200 ggtgseyavvvarsksllgPyewkkknpiltsr 232
                         s+ +  ++ +++l gP++  k+   + s 
      EEA21371.1 214 LTGWSTNDNAYSYATNLAGPWSSWKTFATVGSD 246
                     6666667778888889******99887777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (441 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       341  (0.0190195); expected 358.6 (0.02)
Passed bias filter:                      240  (0.0133861); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 3022.05
//
Query:       EEA21372.1  [L=516]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.8e-16   59.0  54.7    1.3e-14   54.0  38.8    2.2  2  MFS_1      Major Facilitator Superfamily
    5.3e-09   35.5   7.7    5.3e-09   35.5   7.7    2.5  3  Sugar_tr   Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.0  38.8   1.4e-18   1.3e-14      35     309 ..      88     404 ..      50     409 .. 0.73
   2 !    7.5  14.7   0.00018       1.6      73     172 ..     388     485 ..     370     504 .. 0.78

  Alignments for each domain:
  == domain 1  score: 54.0 bits;  conditional E-value: 1.4e-18
       MFS_1  35 gllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfa.sslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagf 130
                    +++  +g +++ l+l++l+  fG  ++ll+++++   g ++ +l++ +  + ++ ++r++ Gl++++ + +g  +++++f   erg ++  + + +
  EEA21372.1  88 ADTVATAIAGLLAGPLILMPLIHIFGCCSILLWSMVAATCGsIWSALMTkPDQYiAFTLSRLFVGLFSATPTILGPQMLVEIFFLHERGTVFNTFLVWS 186
                 334445555667777777***********************666666878555559******************************************* PP

       MFS_1 131 slGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeeekgtgpaplvp................awkallkdpvlw... 210
                  +G+++gp lgg+++s++ W++ f+   ++  ++++l++l+l e+  +r+  +  ++     p+++++                ++ka l++   w   
  EEA21372.1 187 TFGTVIGPTLGGFIVSHAPWPWQFWWTVALQGVVVLLAFLFLEETGFTREDGKVYPR----RPSGFIQnrvatyfpgtsvahvgGFKAALHSA--Waqi 279
                 **********************************99988888777666666666666....44444444444444444444455455555555..4444 PP

       MFS_1 211 ........illialllfffgfsg.lltllplylqevlgls.....glllaglllallalvgailallagrls.dr............lgrrrrlllal. 281
                         il+ ++ll+  g++  + tll ++lq+    +     +  +++ ++ +++ +ga+++l++g +  dr            ++++ rl     
  EEA21372.1 280 ligvtpvtILVGVFLLGVSGWFVsFNTLLSVFLQDPVEVGgygfsA-QQNA-AFTFTMWIGAAVSLIWGHFFnDRiplyfvakysgtWKPEYRLHSLWv 376
                 4444455678888888888888899999999977765555555634.5555.47777778888888999999899999998888888888777766650 PP

       MFS_1 282 lllllaalglallavtssavllllvlvl 309
                 +++l+  +gl ++++t  ++l+++vl++
  EEA21372.1 377 PAFLIQPIGLGIVGATLQYHLHYMVLAV 404
                 5555567899999999888888887765 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.00018
       MFS_1  73 alglllllfasslw.lllvlrvlqGlgagalfpagaaliadwfpk..eergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlf 168
                 ++g + l + + ++ +l+v+ +l  + + a+ p+++ ++++ f+k  +e +  +g++ +g++lG+ +   + ++ a ++g  ++f ++a++sl++fvl+
  EEA21372.1 388 IVG-ATLQY-HLHYmVLAVGTFLVTASSVAISPVAINYLVECFMKypTELNCILGIYRLGIGLGIPFF--IDAWRA-QVGVGWIFGMMAVLSLVLFVLI 481
                 222.22223.556768****************************976688888888888888888666..566666.99******************75 PP

       MFS_1 169 llll 172
                 ++l+
  EEA21372.1 482 VILM 485
                 5554 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.5   7.7   5.9e-13   5.3e-09      44     194 ..      83     231 ..      49     245 .. 0.83
   2 ?   -3.4   0.7      0.35   3.2e+03     325     329 ..     298     302 ..     260     352 .. 0.53
   3 ?   -2.6   4.6      0.21   1.9e+03     292     429 ..     405     474 ..     387     487 .. 0.52

  Alignments for each domain:
  == domain 1  score: 35.5 bits;  conditional E-value: 5.9e-13
                 ...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHH CS
    Sugar_tr  44 ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvsl 142
                 s  ++  +v+ +++G ++G l++++l+++fG +++ll + v +  g++ +a+ ++  ++ +++++R++vG++  + ++l P  + Ei   + Rg++   
  EEA21372.1  83 SLNDMADTVATAIAGLLAGPLILMPLIHIFGCCSILLWSMVAATCGSIWSALMTKPDQYIAFTLSRLFVGLFSATPTILGPQMLVEIFFLHERGTVFNT 181
                 444577899*********************************************8899999999*********************************** PP

                 HHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHH.HHHHHHGGGS--- CS
    Sugar_tr 143 yqlaitfGilvaaifglglnktsnadgwrillglqlvpa.llllilllflPES 194
                 + ++ tfG +++ ++g ++        w++ ++ ++++  +++l+++lfl+E+
  EEA21372.1 182 FLVWSTFGTVIGPTLGGFIVSHAP---WPWQFWWTVALQgVVVLLAFLFLEET 231
                 ****************99977777...77777776666514556667899988 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 0.35
                 HHHHH CS
    Sugar_tr 325 agmai 329
                 +g ++
  EEA21372.1 298 SGWFV 302
                 22222 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 0.21
                 HHHHHHHHHHHHHHHHH.HHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHH CS
    Sugar_tr 292 vtiivgvvnfvatfvai.flvdrfGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskala 389
                 +t++v +  ++++ vai +lv+ f + ++ l +++g   + + lgi                                                     
  EEA21372.1 405 GTFLVTASSVAISPVAInYLVECFMKYPTELNCILGIYRLGIGLGI----------------------------------------------------- 450
                 5555555555555555445555555555555555555555555552..................................................... PP

                 HHHHHHHHHHHHHHHHHHHHHCHHH.T-HHHHHHHHHHHHH CS
    Sugar_tr 390 iavavnwlanflisllfpiiteaig.ggyvflvfaglavlf 429
                                  p++ +a   + +v+++f+++avl+
  EEA21372.1 451 -----------------PFFIDAWRaQVGVGWIFGMMAVLS 474
                 .................222222222233333333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (516 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       890  (0.0496402); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.27s 00:00:00.90 Elapsed: 00:00:00.48
# Mc/sec: 3260.97
//
Query:       EEA21373.1  [L=338]
Description: rRNA processing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.3e-16   60.0   0.1    6.7e-15   55.3   0.1    2.4  1  Fcf1        Fcf1
  ------ inclusion threshold ------
        1.4    7.7   9.4        1.8    7.3   9.4    1.1  1  DUF4551     Protein of unknown function (DUF4551)
        9.8    5.9  15.5         18    5.0  15.5    1.4  1  RR_TM4-6    Ryanodine Receptor TM 4-6


Domain annotation for each model (and alignments):
>> Fcf1  Fcf1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.3   0.1   1.1e-18   6.7e-15       1      99 []      51     195 ..      51     195 .. 0.89

  Alignments for each domain:
  == domain 1  score: 55.3 bits;  conditional E-value: 1.1e-18
                 HHCTS-EEEEEEHHHHHHHHHCT........-HHHHHHHT.T.SEEE----...SS---HHHHHHHHH-B....TB-TT-EEEE-.............. CS
        Fcf1   1 ktLqakvkpliTqCviaeleklg......kklkealkiak.t.ferlkCnh...kkptsaddClvsvvkk....kknkkryivAt.............. 70 
                 +tLq+k kpl+++C++a++++++      +k +  +++     +  ++C+h   ++p+++ +Cl+s++ +     +nk++yi+At              
  EEA21373.1  51 RTLQGKAKPLLSKCSLAAIMAAQpinpktNKPYRPFHLPPpAeLPLRHCSHnddNTPIDEVECLLSLLCPntdtMRNKEHYILATaepvalphddlksd 149
                 69*********************88765544556666666435999*****9988899***********95554289********************** PP

                 .................S-HHHHHHHHTSTT--EEEEE--EEEE-- CS
        Fcf1  71 .................qDkdlrrrlrkipgvPilyikrsvmvlEk 99 
                                  +  +lr+++r++pgvPi+y+krsvmvlE+
  EEA21373.1 150 npkqrrqaealmekrseKALALRSAARAVPGVPIIYVKRSVMVLEP 195
                 **************98888899**********************97 PP

>> DUF4551  Protein of unknown function (DUF4551)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   9.4   0.00031       1.8     104     258 ..     146     308 ..     128     324 .. 0.49

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.00031
     DUF4551 104 lkselllskdkkselfkvspskase.kksrressgaa....kkssslnessldakekeektvskksqlslsl.......selrklseeekeelesekal 190
                 lks++ +++ + ++l++   +ka   + ++r   g++    k s+ + e+   + +++ + +++ks+ ++         s   k ++e + e+ + ++ 
  EEA21373.1 146 LKSDNPKQRRQAEALMEKRSEKALAlRSAARAVPGVPiiyvKRSVMVLEPFS-TPSEKVRLGVEKSKFKIGMeaaldvvS-GLKRKREDE-EEGPSTTA 241
                 5666666666666666555554443144556666666887766666656554.666667777778887777655533311.222222222.33333455 PP

     DUF4551 191 kslrsasrplPesllsrapkppsspkeppssslskderdskseess.........qvelrlgsvlsrlllrslatss 258
                 k +    +  P++l++++pk+ ++ ++p+++ ++k++++ +++es+         +     +sv ++         +
  EEA21373.1 242 KDRHAKKAKAPNPLSMKKPKRREK-PKPEEQGKKKEKKQDQEKESRddgaedkmvD-AEGEESVKKKR--------K 308
                 555555555555565566643322.2333333334444444444443344433221.11112222222........2 PP

>> RR_TM4-6  Ryanodine Receptor TM 4-6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0  15.5    0.0031        18      82     153 ..     238     315 ..     204     324 .. 0.45

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0031
                 XXXXXXXXXX.......XXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXX..........XXXXXXXXXXXXXXXX CS
    RR_TM4-6  82 ptpelkkkla.......eeeeaeeekeeeeepeaeaeekadaengekeekekekeeeekeseeeeeekkkkkkakskkk 153
                  t ++k ++a         ++++ +++e+ +pe++ ++k++++++eke+++   e++  ++e ee  kkk+k+++++ k
  EEA21373.1 238 ST-TAKDRHAkkakapnPLSMKKPKRREKPKPEEQGKKKEKKQDQEKESRDDGAEDKMVDAEGEESVKKKRKRKHKSAK 315
                 22.1122221122233322333444444444444444444444445444444333333333333333333333333222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (338 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1738  (0.0969379); expected 358.6 (0.02)
Passed bias filter:                      722  (0.04027); expected 358.6 (0.02)
Passed Vit filter:                       148  (0.00825478); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.68u 0.32s 00:00:01.00 Elapsed: 00:00:00.48
# Mc/sec: 2104.11
//
Query:       EEA21374.1  [L=88]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.8e-18   64.1   4.0    1.2e-17   63.7   4.0    1.2  1  Cmc1      Cytochrome c oxidase biogenesis protein Cmc1 like


Domain annotation for each model (and alignments):
>> Cmc1  Cytochrome c oxidase biogenesis protein Cmc1 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.7   4.0   6.7e-22   1.2e-17       1      68 [.       1      69 [.       1      70 [. 0.96

  Alignments for each domain:
  == domain 1  score: 63.7 bits;  conditional E-value: 6.7e-22
        Cmc1  1 mhkklkkkarkeCaelikalaeChkd.rllkvvgkCneekeamkkClkeyrtderlkdaekdriiekrl 68
                mh +l++  + +C+e+++al+eCh++ +l+k++g+Cn++k+++++Cl ++r +++++++ ++ ++++r 
  EEA21374.1  1 MHSHLHTPENINCEEIMNALDECHSRgFLWKAMGQCNDIKRDVNRCLGAERAKRAKQNRDQAMERRARV 69
                9*******************************************************9999999999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (88 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       893  (0.0498076); expected 358.6 (0.02)
Passed bias filter:                      344  (0.0191868); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.27s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 636.69
//
Query:       EEA21375.1  [L=536]
Description: rRNA processing protein Pwp1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-15   57.8   3.5    0.00065   20.5   0.2    5.7  5  WD40            WD domain, G-beta repeat
    4.6e-06   25.6   1.5     0.0015   17.3   0.2    2.6  3  Nup160          Nucleoporin Nup120/160
    5.2e-06   26.7   0.2       0.04   14.2   0.1    4.7  6  ANAPC4_WD40     Anaphase-promoting complex subunit 4 WD40 dom
  ------ inclusion threshold ------
      0.064   13.5   2.4       0.15   12.4   0.0    2.4  2  DUF4241         Protein of unknown function (DUF4241)


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0     0.017        75      21      38 .]     204     221 ..     183     221 .. 0.92
   2 !   10.3   0.0   0.00024       1.1      10      38 .]     261     291 ..     259     291 .. 0.73
   3 !   13.0   0.0   3.2e-05      0.14       3      34 ..     297     330 ..     295     331 .. 0.81
   4 !   20.5   0.2   1.5e-07   0.00065       2      38 .]     389     427 ..     388     427 .. 0.81
   5 !    5.4   0.0    0.0086        39      18      38 .]     453     474 ..     441     474 .. 0.67

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.017
                 TSSEEEEEETTSEEEEEE CS
        WD40  21 dgawlasGsdDgtvriWd 38 
                 +g+++a G++ + + iWd
  EEA21375.1 204 SGNFVAVGTMEPDIEIWD 221
                 799*****99*******9 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00024
                 S.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS
        WD40  10 H.ssvtsla.fspdgawlasGsdDgtvriWd 38 
                 H +sv +l+ + ++ ++las+s D tv++Wd
  EEA21375.1 261 HvDSVLALSaNRQHRNLLASASADLTVKLWD 291
                 5555666654445556689999********9 PP

  == domain 3  score: 13.0 bits;  conditional E-value: 3.2e-05
                 EEEEEESSSS.EEEEEEETTSSE.EEEEETTSEE CS
        WD40   3 clrtltGHss.vtslafspdgaw.lasGsdDgtv 34 
                 c +++  H++ +++l+++p  +  l+sGs+D+tv
  EEA21375.1 297 CAKSYNYHKDkICALDWNPRESTiLLSGSYDRTV 330
                 7788888*666****98888888446*******9 PP

  == domain 4  score: 20.5 bits;  conditional E-value: 1.5e-07
                 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 
                 ++++tl +H +sv+s++ +++   +l++Gs D+ v+iWd
  EEA21375.1 389 KPVWTLQAHdDSVSSFDiNPRVPGFLVTGSTDKQVKIWD 427
                 7899*****888**9975444444499***********9 PP

  == domain 5  score: 5.4 bits;  conditional E-value: 0.0086
                 EETTSSE..EEEEETTSEEEEEE CS
        WD40  18 fspdgaw..lasGsdDgtvriWd 38 
                  +p+ ++   ++Gs +g v +Wd
  EEA21375.1 453 PDPEVSFrlAVAGS-KGVVQVWD 474
                 33444446345899.*******9 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.2   3.3e-07    0.0015     207     261 ..     250     306 ..     243     327 .. 0.67
   2 !    6.1   0.0   0.00084       3.7     232     285 ..     413     464 ..     411     472 .. 0.83
   3 ?   -0.4   0.0     0.073   3.3e+02     238     254 ..     466     482 ..     460     488 .. 0.81

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 3.3e-07
                 -SS---TT-ECEEEEET.......TTTEEEEEETT-EEEEEETTTTEEEEEEE--.- CS
      Nup160 207 srrksgasvalsldvavavvei..gqtylfalsrdgkLrvWnlltgkclatidllrd 261
                 +++ ++a+ +  +d + a +    ++++l+++s d ++++W+l+t++c+ + +  +d
  EEA21375.1 250 KKKSKKANDEYHVDSVLALSANrqHRNLLASASADLTVKLWDLNTQTCAKSYNYHKD 306
                 333333333444444444444445*************************99777733 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.00084
                 EEEEEETT-EEEEEETTTTEEEEEEE--.-SSSTTS--SSEESEEESSSSEEEE CS
      Nup160 232 ylfalsrdgkLrvWnlltgkclatidllrdeeaqdessskstldpaesslirvs 285
                 +l++ s d+ +++W+++++k+ ++ + +  e+ +++s+s    dp+ s++++v+
  EEA21375.1 413 FLVTGSTDKQVKIWDTANDKPNMVVSRK-LEVGKVFSTSF-APDPEVSFRLAVA 464
                 6788899**************9997776.68999999999.8888888888887 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 0.073
                 TT-EEEEEETTTTEEEE CS
      Nup160 238 rdgkLrvWnlltgkcla 254
                 + g+++vW+++t+  ++
  EEA21375.1 466 SKGVVQVWDTSTNAAVR 482
                 6689********98876 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       2.5   1.1e+04      35      68 ..     131     164 ..     127     190 .. 0.70
   2 ?   -2.0   0.0         1   4.5e+03      48      66 ..     203     221 ..     202     226 .. 0.86
   3 !   14.2   0.1     9e-06      0.04      47      90 ..     272     314 ..     252     316 .. 0.88
   4 ?    1.3   0.0     0.095   4.2e+02      38      70 ..     348     381 ..     340     388 .. 0.80
   5 ?    3.1   0.0     0.027   1.2e+02      27      72 ..     389     433 ..     386     448 .. 0.82
   6 ?    0.6   0.0      0.15   6.9e+02      52      74 ..     460     482 ..     434     489 .. 0.76

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 2.5
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdgevrlldae 68 
                  +++d+e ++L+    ++lL  +  + ev  l+++
   EEA21375.1 131 EDNDEEREELQILGTDNLLIAGKLEDEVAHLEVY 164
                  5666666777777777888887777777776665 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1
  ANAPC4_WD40  48 pdgklLavaysdgevrlld 66 
                   +g++ av++ +  +++ d
   EEA21375.1 203 TSGNFVAVGTMEPDIEIWD 221
                  6899******999999987 PP

  == domain 3  score: 14.2 bits;  conditional E-value: 9e-06
  ANAPC4_WD40  47 kpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgWg 90 
                  ++  +lLa a +d +v+l d +++++ +s++++++k ++ l+W+
   EEA21375.1 272 RQHRNLLASASADLTVKLWDLNTQTCAKSYNYHKDK-ICALDWN 314
                  456689*****************************5.******7 PP

  == domain 4  score: 1.3 bits;  conditional E-value: 0.095
  ANAPC4_WD40  38 dsevrsLaWkpdg.klLavaysdgevrlldaesg 70 
                   s v++L+W p + +++ v ++ g v  +da ++
   EEA21375.1 348 ASDVENLRWDPHDpNFFYVTTDTGLVYKYDARNA 381
                  6789*****9865378889999999888888775 PP

  == domain 5  score: 3.1 bits;  conditional E-value: 0.027
  ANAPC4_WD40  27 qrvwtleedkedsevrsLaWkpd.gklLavaysdgevrlldaesgkv 72 
                  + vwtl  +++d +v+s+  +p    +L+ +  d +v++ d  + k 
   EEA21375.1 389 KPVWTL--QAHDDSVSSFDINPRvPGFLVTGSTDKQVKIWDTANDKP 433
                  679999..8999999999999873469999***********999875 PP

  == domain 6  score: 0.6 bits;  conditional E-value: 0.15
  ANAPC4_WD40  52 lLavaysdgevrlldaesgkvvh 74 
                   Lava s+g v++ d ++   v+
   EEA21375.1 460 RLAVAGSKGVVQVWDTSTNAAVR 482
                  49************999887765 PP

>> DUF4241  Protein of unknown function (DUF4241)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   1.7      0.42   1.9e+03      92     129 ..      57      94 ..      14     110 .. 0.57
   2 ?   12.4   0.0   3.2e-05      0.15      43     108 ..     324     389 ..     312     447 .. 0.85

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.42
     DUF4241  92 acffDakafealsefeeslleeepkkdeyddyfeelfe 129
                 +  +D+++ e+ s+   + +++  ++d++++y  +++ 
  EEA21375.1  57 GDAMDEDTNEKTSKKTSKDEDHDDEDDDLKEYNLDHYD 94 
                 33455555555555555333333333355555444443 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 3.2e-05
     DUF4241  43 egaedrvaaarlvfsdepavrwelAllgeqdlaeleegeffgygVDaGlacffDakafealsefee 108
                 + +++ v+aa ++  d +a rw+ A+  e+   +  ++ ff++  D+Gl+  +Da ++ a  + ++
  EEA21375.1 324 GSYDRTVVAADMRTPDAKAPRWQVASDVENLRWDPHDPNFFYVTTDTGLVYKYDARNAPATPAESK 389
                 558999*******************99988877778999****************99988777666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (536 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1121  (0.0625244); expected 358.6 (0.02)
Passed bias filter:                      591  (0.0329634); expected 358.6 (0.02)
Passed Vit filter:                        64  (0.00356964); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.31s 00:00:00.94 Elapsed: 00:00:00.45
# Mc/sec: 3552.73
//
Query:       EEA21376.1  [L=114]
Description: hypothetical protein PMAA_051860 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (114 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       333  (0.0185733); expected 358.6 (0.02)
Passed bias filter:                      222  (0.0123822); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.35u 0.27s 00:00:00.62 Elapsed: 00:00:00.41
# Mc/sec: 832.47
//
Query:       EEA21377.1  [L=257]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (257 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       585  (0.0326287); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 1841.33
//
Query:       EEA21378.1  [L=711]
Description: RNA polymerase I specific transcription initiation factor RRN3 superfamily [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.2e-175  585.3   0.0   1.2e-175  585.3   0.0    2.0  2  RRN3      RNA polymerase I specific transcription initiation 


Domain annotation for each model (and alignments):
>> RRN3  RNA polymerase I specific transcription initiation factor RRN3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  585.3   0.0  6.6e-180  1.2e-175       3     557 ..     103     673 ..     101     674 .. 0.93
   2 ?  -12.2  15.5         1   1.8e+04     221     251 ..     676     708 ..     673     711 .] 0.37

  Alignments for each domain:
  == domain 1  score: 585.3 bits;  conditional E-value: 6.6e-180
        RRN3   3 fskkmlkefVrnALeekekg.dseqydeLleqfsekk......eeseapslaelkqllkalssvvsrLershssLveailslkWlerdeafvkayieFl 94 
                  s+++++e++r+A++++ +g dse yd+++e+f++++      e+++ ps++++k +++ l s+v+ L+r++s+Lv+a+l  +W++rde++vk++++Fl
  EEA21378.1 103 KSAALVREEIRRAIQRHVSGvDSEGYDQIKEIFTTDPketsdeESPDIPSPTSMKRHMMGLLSNVAALNRDCSGLVHAVLGSEWVGRDESYVKLFVRFL 201
                 57889************8877**************9999*99999****************************************************** PP

        RRN3  95 geLvsaqpkylsevlsklvqnfteqsessaalpessevtrrevyerlHelLkkllsliPtlasvlqpllakkfPhkreskkaqvtYirnllklteycpe 193
                 g+L++++ +y++ vl++lv+ f e ++ + +lp++ +v+++++y+r+H++L+++++l P+ +s+l+pll+++fP++++s++a+v Y+rnl+k+++y+pe
  EEA21378.1 202 GNLAATHTGYMRVVLKMLVTYFGEIPKGTGRLPGYASVSHEDIYDRVHMALRYIMQLLPAGSSTLSPLLSQQFPFDTDSARANVFYTRNLIKVIDYAPE 300
                 **************************999********************************************************************** PP

        RRN3 194 lsedileliverlikiDVeiqveledlddeedeeleeelee....deddedddeddeesdlddlssdeeaeedeekdeeeeslkkikelvekLDailtl 288
                 l+ dil+li+erlikiDV+iqv++ed++de  e+  eel++    +        d+e+sd++++ sd+ea+       e+++l+++k++++k+D++++ 
  EEA21378.1 301 LRGDILSLITERLIKIDVQIQVDMEDFEDEVGEDILEELARpfeiE------YIDEEDSDDESILSDDEADA------EAKRLQTVKDNISKVDSMIDQ 387
                 ***********************************99988854321......33333455666666644444......45789**************** PP

        RRN3 289 lfehlekkfssestkeeeeeeeglelfntLlslFkstiLptyksrhvqFllFhfssldpeladkflglLidialsknepaetRvaAaaYlaSfvaRAkf 387
                 lfe+++ +f++       +++ +l++ + L+++F s iLpty+srh+qFllFhfs+  p+l+dkf++++++i+ sk++++++R++AaaYl+SfvaR+k+
  EEA21378.1 388 LFEYYSTHFQHG------TDAVKLQTLDLLIHHFVSYILPTYRSRHTQFLLFHFSQSTPDLVDKFVTSCMEIINSKSRSPIMRQSAAAYLGSFVARGKH 480
                 *******55555......5777789************************************************************************** PP

        RRN3 388 vskeqvrkvvslLvewlekyvdereeevqgpdlkrhkvFYavaQAllYifCFRwrdLlkeeee.........kekdrkwlqel.kvlqrviiskLnPLk 476
                 +s+  vr+++++L + l++ ++++e++++gp+l+ ++ FYa +QAllYifCFRwrdL++++ee         + +d ++ + + ++l r+i+s+LnPLk
  EEA21378.1 481 LSSRAVRDIFEMLGKNLSNLLETYERNCHGPNLRGYGPFYASMQALLYIFCFRWRDLTTTAEEndgiededpDLEDVTFPEAVrDPLYRAIHSRLNPLK 579
                 **********************************************************998878999999997799999999***************** PP

        RRN3 477 vcspnVveeFakiaqalqllycysilesnkrerlsgiesks.........ta....kkkqeaaeLdsyFPFDPykLprskrfieelYveWseva 557
                 +csp++v+eFa+ia++l+++y+y++lesnkr r+s+++s +         ++    + ++ a  Ld+yFPFDPy+Lprs+r++e++Y+eW+ ++
  EEA21378.1 580 ICSPAIVTEFARIAHHLGFMYIYTLLESNKRLRVSSFRSITtlsdprfsiVEretrAGNDGADVLDAYFPFDPYQLPRSRRWLEGDYIEWRGIP 673
                 **************************************988766666555005666999999****************************9875 PP

  == domain 2  score: -12.2 bits;  conditional E-value: 1
        RRN3 221 ddeedeeleeeleededdedddedd..eesdld 251
                 dd++d++ ++++e+d d +ddd+dd  +++d d
  EEA21378.1 676 DDQADDDSDSAAEQDVDVDDDDDDDptATDDED 708
                 344444433333333333333333333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (711 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       686  (0.038262); expected 358.6 (0.02)
Passed bias filter:                      477  (0.0266049); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.74u 0.30s 00:00:01.04 Elapsed: 00:00:00.47
# Mc/sec: 4580.53
//
Query:       EEA21379.1  [L=408]
Description: lipase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.1e-43  149.6   0.0    1.5e-43  149.1   0.0    1.2  1  Abhydrolase_3  alpha/beta hydrolase fold
    1.2e-09   37.6   0.1    4.2e-09   35.8   0.1    1.7  1  COesterase     Carboxylesterase family
     0.0021   17.9   0.0      0.007   16.2   0.0    1.8  2  Abhydrolase_2  Phospholipase/Carboxylesterase
     0.0068   15.9   0.0        1.5    8.3   0.0    2.2  2  Peptidase_S9   Prolyl oligopeptidase family
     0.0095   16.6   0.7      0.018   15.6   0.7    1.4  1  Abhydrolase_6  Alpha/beta hydrolase family
  ------ inclusion threshold ------
      0.017   14.7   0.0      0.026   14.1   0.0    1.2  1  DUF2974        Protein of unknown function (DUF2974)
      0.059   12.0   0.1        1.3    7.6   0.0    2.1  2  AXE1           Acetyl xylan esterase (AXE1)
      0.087   12.7   0.1       0.17   11.7   0.1    1.4  1  Lipase_3       Lipase (class 3)


Domain annotation for each model (and alignments):
>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  149.1   0.0   6.9e-47   1.5e-43       1     209 [.     140     377 ..     140     379 .. 0.92

  Alignments for each domain:
  == domain 1  score: 149.1 bits;  conditional E-value: 6.9e-47
                    EEEE--STTTS--TTTTHHHHHHHHHHHTSEEEEEE---TTTS-TTHHHHHHHHHHHHHHHTHHHHTETTCEEEEEEETHHHHHHHHHHHHHHHTT CS
  Abhydrolase_3   1 lvyfHGGGfvlgsldthdalcrelakelgavvvsvdYrlAPehpfPaavedalaalrwlaeqawelgadpsrivlaGdSaGGnlaaavalrardeg 96 
                    +v fHGGGf+lgs++ +  +++ + ke++av vsv+YrlAPe pfPaav+d+++al +la++a elg+d+srivl G S GGnla  v lr++ + 
     EEA21379.1 140 VVNFHGGGFTLGSATDDSYWAKCVLKETDAVFVSVEYRLAPERPFPAAVDDGVEALLYLAAHAGELGIDASRIVLTGFSSGGNLAITVPLRLQHRI 235
                    699***********************************************************99*****************************996 PP

                    ---..........................EEEEEEESE-SSTSSTTSHHHHHCHHTTTSSSSCHHHHHHHHHHHSS.GGGGGSTTTSGGGCS-... CS
  Abhydrolase_3  97 epk..........................vagqvliyPvtdlertesesikkaeeladgplltraaldlfwrlylp.eadrddplaspllaed... 162
                    ++                           +++++ +yP++d+    s ++++a ++  g++++   + lf + ylp + +r +p asp +a+d   
     EEA21379.1 236 QNDagsdivnvvepldstqnlvsgqgnlqIVATFAWYPLLDF--VASRAHRRAMSVIPGKTMPSFLTTLFDESYLPdRTERFSPFASPERASDeil 329
                    555899*********************************999..333444456677888899999999999****9788888*********76788 PP

                    SST--.-EEEEEETT-TTHHHHHHHHHHHHHTT--EEEEEETTEETTG CS
  Abhydrolase_3 163 lsglp.ptlvvvaefDplrdegeayaerlraagvevelieyegmvHgf 209
                     +glp  ++++++e D+l +eg+++ +rl+++g++v+ + +e+++H++
     EEA21379.1 330 AAGLPhDIFLYTCEWDMLLHEGQRFVRRLEKMGKKVRAMMVEKVPHAW 377
                    88999459**************************************97 PP

>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.8   0.1   1.9e-12   4.2e-09      95     199 ..     127     224 ..     120     235 .. 0.90

  Alignments for each domain:
  == domain 1  score: 35.8 bits;  conditional E-value: 1.9e-12
                 ESSSSSTTSSEEEEEEE--STTTS-BGCG..S-THHHHHHHTSEEEEE----HHHHH-B-SSTTSBS-HHHHHHHHHHHHHHHHGGGGTEEEEEEEEEE CS
  COesterase  95 PkekkeakkklPVlVwihGggfqtgsase..ydgsaLaaegnvivVtinYRlGvlGFlstgdeeapGNvGllDqvlALrWVkenIasFGGdpervtlfG 191
                 P++++++++ +PV+V +hGggf+ gsa++  y ++  ++e + + V+++YRl +         e p  +++ D v AL ++  +  + G d +r+ l G
  EEA21379.1 127 PSSSTDSQRPFPVVVNFHGGGFTLGSATDdsYWAKCVLKETDAVFVSVEYRLAP---------ERPFPAAVDDGVEALLYLAAHAGELGIDASRIVLTG 216
                 8888999********************88899999999999***********86.........556667889*************************** PP

                 ETHHHHHH CS
  COesterase 192 esAGaasv 199
                  s+G+ ++
  EEA21379.1 217 FSSGGNLA 224
                 ****9765 PP

>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.0       3.7   8.4e+03      13      43 ..     136     167 ..     132     173 .. 0.61
   2 !   16.2   0.0   3.1e-06     0.007      98     130 ..     203     235 ..     185     239 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 3.7
                    --EEEEEE--TT--S.HHHHHHHH.TT--TTE CS
  Abhydrolase_2  13 aqavviflHGlGdsg.hawaeaakteaalpni 43 
                    + +vv+ +HG G +   a+ +    ++ l+++
     EEA21379.1 136 PFPVVVNFHGGGFTLgSATDDSYWAKCVLKET 167
                    55789999998877535554444445555555 PP

  == domain 2  score: 16.2 bits;  conditional E-value: 3.1e-06
                    HHTT--GGGEEEEEETHHHHHHHHHHHT-SS-- CS
  Abhydrolase_2  98 lkkgipssriiigGFSqGaalalylaltlpkkl 130
                     + gi++sri++ GFS G+ la+   l l++++
     EEA21379.1 203 GELGIDASRIVLTGFSSGGNLAITVPLRLQHRI 235
                    4567*******************9999988876 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.3   0.0   0.00066       1.5      45      80 ..     188     226 ..     185     233 .. 0.83
   2 !    5.4   0.0    0.0051        12     142     197 ..     333     386 ..     292     399 .. 0.76

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00066
                   HHHHHHHHHHHHHTT...S--GGGEEEEEETHHHHHHHH CS
  Peptidase_S9  45 fdDfiaaaealakeg...yvdserlaitGgSyGGyltga 80 
                   +dD ++a+ +la++     +d++r+++tG S GG l+ +
    EEA21379.1 188 VDDGVEALLYLAAHAgelGIDASRIVLTGFSSGGNLAIT 226
                   78889999999776555689**************99865 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.0051
                   ---EEEEEEETT-SSS-THHHHHHHHHHH--S-SEEEEEETTS-SSTTSSHHHHHH CS
  Peptidase_S9 142 aypplLlihGlaDdrvppaealklvaaLqkkgknvlllifpdegHgvgkprakvee 197
                     ++++l + ++D      e+ ++v++L+k gk+v+ ++  +  H   k+ +  + 
    EEA21379.1 333 LPHDIFLYTCEWDMLL--HEGQRFVRRLEKMGKKVRAMMVEKVPHAWDKSPNPFRD 386
                   5667777777777655..8999***********************87776665555 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.7   8.2e-06     0.018       5     192 ..     144     362 ..     139     386 .. 0.41

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 8.2e-06
                    --GC...........GCHHHHHHHHCCTCEEEEE--TTSTS-GGCS--HHH.CHHH...HHHHCCTT.....TTSEEEEEETCHHHHHHHHHHCC. CS
  Abhydrolase_6   5 HGagss......assWlvapLaallaagvhvlapDlpGhGrsdpppldled.ladl...aalldelaa...gggpvvlvGHSlGGalalaaapla. 86 
                    HG+g++       s W +  +++   a +  +++ ++   +  p p +++d +++l   aa++    +   ++ ++vl G S GG la     ++ 
     EEA21379.1 144 HGGGFTlgsatdDSYW-AKCVLKETDAVF--VSVEYRLA-PERPFPAAVDDgVEALlylAAHAG---ElgiDASRIVLTGFSSGGNLAIT---VPl 229
                    5655444333334445.234444444445..55555422.112233333333333322333333...244699999**********9999...555 PP

                    ................EEEEES-...................----TTTS----TTHHHHHHTT-CCCCHCCHS-HSCCCCHHHC..CCCHCHCCC CS
  Abhydrolase_6  87 ..............lvvgvlldp..........pp.......talpagllaaalelllallallrllawlsreplprlfladeda..daawrarla 149
                                  +    +++p           +        a+ ++l   a + +++++++ +  +++s  +l+ ++++   +   ++ ++r++
     EEA21379.1 230 rlqhriqndagsdiV---NVVEPldstqnlvsgQGnlqivatFAWYPLLDFVASRAHRRAMSVIPGKTMPS--FLT-TLFD---EsyLPDRTERFS 316
                    556666865543221...55555333333222211222222222222222222222223333333322222..233.3333...111233333333 PP

                    GHHHHCCHHCHTTCCHHTT-TTGC.....EEECTT-CHHHHCHHCCCH CS
  Abhydrolase_6 150 rlaallaglgllpaaawadlpvpl.....lvlggeDplvprllerlla 192
                    + a    + ++  aa +++   ++     ++l+++ + v+rl  + + 
     EEA21379.1 317 PFASPERASDEILAAGLPHDIFLYtcewdMLLHEGQRFVRRL--EKMG 362
                    333333333333344444444444333244556666666655..4444 PP

>> DUF2974  Protein of unknown function (DUF2974)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   1.2e-05     0.026      70     110 ..     193     236 ..     183     254 .. 0.75

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 1.2e-05
     DUF2974  70 sAlkYlnkileeseg...kiylgGhSkGGnlAvyaamnaeddlq 110
                 +Al Yl   + e      +i+l+G+S GGnlA+ + +++++++q
  EEA21379.1 193 EALLYLAAHAGELGIdasRIVLTGFSSGGNLAITVPLRLQHRIQ 236
                 6777777666554322326**************99999776666 PP

>> AXE1  Acetyl xylan esterase (AXE1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0     0.026        57      78     106 ..     132     160 ..     105     166 .. 0.83
   2 ?    7.6   0.0    0.0006       1.3     171     192 ..     207     228 ..     193     240 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.026
                 .SSSSEEEEEEEE-TT--GGGHHHHHHHH CS
        AXE1  78 ekeeklPavvefhGYegsrgeihdllnya 106
                 +++++ P+vv+fhG   + g+++d   +a
  EEA21379.1 132 DSQRPFPVVVNFHGGGFTLGSATDDSYWA 160
                 467899********999999999888887 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0006
                 EEEEEEEEEEETHHHHHHHHHH CS
        AXE1 171 vDeeRvavlGasqGGalalava 192
                 +D +R++ +G s GG la++v 
  EEA21379.1 207 IDASRIVLTGFSSGGNLAITVP 228
                 89*****************985 PP

>> Lipase_3  Lipase (class 3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.1   7.7e-05      0.17      65      94 ..     210     241 ..     186     248 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 7.7e-05
                 EEEEEEEETHHHHHHHHHHHHHHHTT-SS..- CS
    Lipase_3  65 ysivvtGHSLGgalAlLaaldlvengene..k 94 
                  +iv+tG S Gg lA+ ++l l+++ +n+  +
  EEA21379.1 210 SRIVLTGFSSGGNLAITVPLRLQHRIQNDagS 241
                 68********************9998777554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (408 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       452  (0.0252106); expected 358.6 (0.02)
Passed bias filter:                      414  (0.0230911); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 2761.05
//
Query:       EEA21380.1  [L=951]
Description: aspartyl-tRNA synthetase, cytoplasmic [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.2e-71  241.3   0.0      2e-71  240.7   0.0    1.3  1  tRNA-synt_2      tRNA synthetases class II (D, K and N)
    8.2e-20   71.0   0.0    1.3e-19   70.4   0.0    1.3  1  DUF2156          Uncharacterised conserved protein (DUF2156)
      0.002   18.1   0.0     0.0053   16.7   0.0    1.8  1  tRNA_anti-codon  OB-fold nucleic acid binding domain
  ------ inclusion threshold ------
       0.06   12.8   0.1        7.3    6.0   0.0    2.5  2  tRNA-synt_2d     tRNA synthetases class II core domain (F)


Domain annotation for each model (and alignments):
>> tRNA-synt_2  tRNA synthetases class II (D, K and N)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  240.7   0.0   4.4e-75     2e-71       3     312 ..     268     591 ..     266     593 .. 0.93

  Alignments for each domain:
  == domain 1  score: 240.7 bits;  conditional E-value: 4.4e-75
                  CHHHHTHHHHCCSHHHHHHHHHHHHHHHHHHHHHHHTT-EE----SEESS--SSSS--EEEEETTT.TEEE....-E-S-SHHHHHHHHHCTHSEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2   3 elrlknryldlrtekvskvlrlrstvtkavrkyleengfieietPiLsksdteegarlFkvksrekekeff....aLtqspqlylellivagidrvfq 96 
                   +rl nr+ldlrt   ++++rl+s v ++ r  l+e+gfiei+tP L+ s+te+ga  F++       ++f    +L+qspql +++ i++ +drv++
   EEA21380.1 268 RTRLSNRILDLRTGTAQAIFRLQSAVGNLWRAALDERGFIEIHTPKLQGSATESGASVFQL-------NYFgrpaFLAQSPQLAKQMAIASDFDRVYE 358
                  689**********************************************************.......88899999********************** PP

                  EEEEE--S--BTTB-S-CEEEEEEEEET-SCHH.HHHHHHHHHHHHHHHHHHCSCCCCCHTTTTTS...EE-SSS-EEEEHHHHHHHHHTS....... CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxx....... RF
  tRNA-synt_2  97 iaraFRaEdsrtdrhlaEFtqieaemsfieeed.imqvleelikslvkevlessakdiefvirrns...kdlkkpfkrltykeaieklnei....... 183
                  i+ +FRaE+s+t rhl+E+t +++em++ e+ + ++++++ +++++++ + ++ ++++e v+++       l+++ + ++++ea+  ln+        
   EEA21380.1 359 IGAVFRAENSNTHRHLTEYTGLDIEMAIEEHYHeMLETIDAVLRNIITGIYSKYRREVEAVKHQFPsedVVLAEKTPVIPFQEAVALLNDSgwrgedg 456
                  ****************************998877****************9999999888887765765667888*************9999999999 PP

                  .....-SS--HHHHHHHHH....HS--SEEEEEEEBGGGSTTCBBBSTTSTTBBSEEEEEETTEEEEEEEEB--SHHHHHHHHHHCCHHSSSGGGGHH CS
                  .....xxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2 184 .....gkdldkaderalvk....keknepvfvtdfPaelkpFyarkeeddkkltesyDllingvElvgGslRiedpeeleeklkskgldeeaeekfsw 272
                       ++dl++ de  l +    k +++ + + +fP + +pFy+  +  d++ t+s+D++++g E+v+G +Ri+dp +lee++k+ g+d   ++ +++
   EEA21380.1 457 elipaDEDLHTRDEIRLGElvkeKYGTDYYIIDKFPVSARPFYTMPDPYDSRYTNSFDMFVRGQEIVSGGQRIHDPTMLEENMKKVGID---PSAMED 551
                  9999977777766654444555588999999**********************************************************...****** PP

                  HHHHHHCT--SEEEEEEEHHHHHHHHCT-SSGGGCSSS-X CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2 273 ylealeyGapphgGlglGldRlvmlllgsesIrdviaFPk 312
                  yle +++Gapph+G g+Gl+R+vmlll++ +Ir +++F +
   EEA21380.1 552 YLEGFRWGAPPHAGAGVGLERFVMLLLKLGNIRLASLFHR 591
                  ***********************************99965 PP

>> DUF2156  Uncharacterised conserved protein (DUF2156)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.4   0.0   2.8e-23   1.3e-19       3     298 .]     638     932 ..     636     932 .. 0.85

  Alignments for each domain:
  == domain 1  score: 70.4 bits;  conditional E-value: 2.8e-23
                 CCCTSSGGGGHHHHHHCCHCCEEEECCTTEEEEEEEECTCEEEECS-EE.CCGHHHHHHHHHHHHHHC.TSEEEEEEE-HHHHHHHHH.CTEEEECCCE CS
     DUF2156   3 llersgsedslsnlalwrdksyyfspsgdalvayrvkggvalalgdPvGdpeawpeaieeflelaaeh.gwrpafygvseelaellae.lglsalrlge 99 
                 l++++g  d+ s+ ++ + ++ ++ p   a+v y   +  a+  gdP++dp+++  +i  fl + +++ +++p+++ vs+++ ell e lg+++l   +
  EEA21380.1 638 LIANYG--DATSTSWTDERYQIWRDPFTGAAVSYVPSYSYAIIPGDPLCDPSQYNRVISSFLHWLKREtKLKPIWILVSPAVEELLGEkLGWRSLSCIA 734
                 566666..777777777777778899**************************************998769****************99899******** PP

                 EEEEEHHHHHTTSGGGHHHHHHHHHHHHCTECEEEEEGGGH.-HHHHHHHHHHHHHHHHHTTCHHHHCCCHHHHCHHHH.TSEEEEEEE.TTEEEEEEE CS
     DUF2156 100 eavvdledftLsGkkfrnvRnainraeraGytveverisdl.spellaelkeiseeWlkqkeatEkgfslglfdelddl.dlrglvvrdeegrivAfts 196
                 e +vd++   ++      v ++i++ae++G++ + +++ +l ++e+++++ +  + Wl+++  +  +  l  + +++d  +   ++++d+eg i Af+ 
  EEA21380.1 735 EERVDPSRNLMA--SDTEVARKIRHAENEGVKLVDVPHGELpPDEIRTKIDKRIQDWLANR--KGTQIHLSEIAPWRDYeHRWYFYATDKEGNIAAFVA 829
                 *****9997555..34566678999999999999999999955677899***********9..555555555555555525667889999**9999998 PP

                 EEEECTTTEEEEEEEEE-TT.STTHHHHHHHHHHHHCHHTT-SEEEEEEE................HHHHHHHHHHHHHTTTCHHHHHHHCT--CEEEE CS
     DUF2156 197 feplngkdglsldlmRrdpdapnGlmefliaelaeelkeegveyvsLgfaplagl.geregagllerllrllleflerdygfegLrrfKlkyqPewepr 294
                 +  l  + g+ +      pdapnG++e ++ ++++++ ++gv+ + +g+ + a+l   ++ +g+  r+l+ ++e++ + +++    +f +k   ++ep 
  EEA21380.1 830 LAMLAPRHGMQVKYSLDFPDAPNGTIEHIVTHAIQTASKSGVKSLTFGAGATAQLtPGHHMKGAKVRMLQHTYEAVAKQFHLTRKSEFRMKLGAHEEPL 928
                 8888844555555555559************************************9777788999****************999999999999999999 PP

                 EEEE CS
     DUF2156 295 Ylay 298
                 Y+ay
  EEA21380.1 929 YIAY 932
                 9998 PP

>> tRNA_anti-codon  OB-fold nucleic acid binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   1.2e-06    0.0053       1      74 [.     147     232 ..     147     234 .. 0.90

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 1.2e-06
                      EEEEEEEEEEEEEEETTEEEEEEEETTEEEEEEEET......HHHHHHHTTS-TTSEEEEEEEEEEC........TTSSEEEEEEEEE CS
  tRNA_anti-codon   1 VtvaGrvtsisdrsggkvifidlrDgtgriqvvlfr......eeatklaenlkeGdvvrvtGrvkrr........pggelelkveeie 74 
                      Vt+ +r++ i+   ++k++f++ r    ++q vl         ++  +ae+l+ G++vrv+G  ++         ++  +el++e++ 
       EEA21380.1 147 VTFTARLHIIR-NISAKLVFLVFRQQLTTFQGVLHAeegkksLGMVHWAERLRTGTIVRVRGIMQSPavpvlgstYHD-IELSIEQLH 232
                      88999999997.888***************************9**********************9988877776666.999888876 PP

>> tRNA-synt_2d  tRNA synthetases class II core domain (F)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.1    0.0061        27      98     171 ..     350     424 ..     338     435 .. 0.59
   2 ?    6.0   0.0    0.0016       7.3     213     233 ..     565     585 ..     542     596 .. 0.85

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.0061
                   S-SSEEEEEEEEEEBSST.-SSSB-SEEEEEEEEEE.ETT--..HHHHHHHHHHHHHHHCTSTEEEEEEECEETTEEE CS
  tRNA-synt_2d  98 kkppikiisigrvfRrda.vDathlaeFhqveglvv.denvs..ladlkgvleellkklfgaevkvrfrpsyfpfteP 171
                    +   ++  ig vfR ++    +hl e++ ++  ++ +e+++  l+++ +vl+++++ ++    k r + +  ++  P
    EEA21380.1 350 ASDFDRVYEIGAVFRAENsNTHRHLTEYTGLDIEMAiEEHYHemLETIDAVLRNIITGIY---SKYRREVEAVKHQFP 424
                   5555678899*******967788999**98876443033221113344444444444443...444555555555555 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.0016
                   EEEEEHHHHHHHHHT-SSGHH CS
  tRNA-synt_2d 213 afGlGveRlamlkygieDiRe 233
                   + G+G+eR+ ml +++ +iR 
    EEA21380.1 565 GAGVGLERFVMLLLKLGNIRL 585
                   67*****************94 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (951 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       997  (0.0556082); expected 358.6 (0.02)
Passed bias filter:                      620  (0.0345808); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.83u 0.30s 00:00:01.12 Elapsed: 00:00:00.45
# Mc/sec: 6350.92
//
Query:       EEA21381.1  [L=447]
Description: hypothetical protein PMAA_051910 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.4e-44  152.8   0.2    1.9e-44  152.4   0.2    1.1  1  DDE_Tnp_1_7  Transposase IS4


Domain annotation for each model (and alignments):
>> DDE_Tnp_1_7  Transposase IS4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  152.4   0.2   1.1e-48   1.9e-44       2     272 ..      69     380 ..      68     399 .. 0.89

  Alignments for each domain:
  == domain 1  score: 152.4 bits;  conditional E-value: 1.1e-48
  DDE_Tnp_1_7   2 pvelFelflpdkilerivkatNayakqk.........kkwleltaeElkaFlGllllmglvrlpsvedyWstkdfyg....npllseiMsreRFeeil 86 
                  p+++F+lf+++++++ +++ tN+ya  k         ++w+ +t  ElkaF+G+++ mg  + p+++dyW+++++ +    n++ls +++  RFe++ 
   EEA21381.1  69 PYQIFSLFFTEDLFKVLADNTNMYAYAKlsknmnphhRNWRSTTPGELKAFVGAQIYMGFTKEPQLKDYWDEEKHNKsvhaNHPLSNYITCFRFEQLK 166
                  9**********************************************************************9995555678***************** PP

  DDE_Tnp_1_7  87 salhladn........................stkkaekdklkkvrelidslnermqkvyrpsqtlvldeslvlfkgrvpfkqylpgkprkvgiklhv 160
                  + +h++++                        s+++ +    +kv  ++d l +  +++y ps+++++de +v  +gr +    +p+kp   g+k++v
   EEA21381.1 167 RFFHISEPsevpggfistyyrpepteeeelqlSEEQLSGIWWHKVHTVFDILRKASKNLYIPSSNISIDEAMVCSHGRSSHTYKMPNKPISQGFKIFV 264
                  ***********************9999888664444488999******************************************************** PP

  DDE_Tnp_1_7 161 lcdsqtgyilalelyegearnlrl..srelgktnalvlrLleplqgkg..rvvvmdnfftslellqeLakkgtyavGtlkknrsglPkeltqklpkge 254
                  l+d   gy + +++  ++++ ++    +el+kt ++v +L+++l + +  + +++dn+fts++l+++L + ++ a+Gt +  ++++P+ l++++  g 
   EEA21381.1 265 LAD--HGYCYYFYPASRTKGVVEVgmAKELTKTGQMVYELVQTLPKDNktYDLYLDNYFTSVNLFKALPEIQVGACGTTRP-HKEFPNLLKNSKIWGH 359
                  ***..9**********999877653378****************965555*******************************.77***99998877776 PP

  DDE_Tnp_1_7 255 llaryg...gplmllkwndrk 272
                  ++  ++   +  m ++  ++k
   EEA21381.1 360 ISHITKfvlSLSMTFSALHGK 380
                  666666553334555555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (447 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       391  (0.0218082); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 3229.13
//
Query:       EEA21382.1  [L=192]
Description: hypothetical protein PMAA_051920 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (192 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       497  (0.0277205); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.41u 0.24s 00:00:00.64 Elapsed: 00:00:00.39
# Mc/sec: 1459.37
//
Query:       EEA21383.1  [L=878]
Description: hypothetical protein PMAA_051930 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-10   40.5   0.1    4.8e-10   39.5   0.1    1.5  1  DUF4470   Domain of unknown function (DUF4470)
      6e-09   35.3   8.7     0.0015   18.5   0.7    4.2  4  TPR_2     Tetratricopeptide repeat
    1.1e-06   28.2   4.3      0.023   14.5   0.6    3.4  3  TPR_1     Tetratricopeptide repeat
    1.9e-05   25.1   4.1        0.2   12.2   0.7    3.5  3  TPR_19    Tetratricopeptide repeat
    2.7e-05   24.6  11.5       0.18   12.7   0.8    4.8  4  TPR_14    Tetratricopeptide repeat
      3e-05   23.6   6.1    0.00012   21.7   2.1    3.0  3  TPR_11    TPR repeat
    8.2e-05   22.8   8.5     0.0018   18.5   4.1    3.8  4  TPR_12    Tetratricopeptide repeat
    8.9e-05   23.1   2.2    8.9e-05   23.1   2.2    3.0  2  TPR_16    Tetratricopeptide repeat
     0.0011   18.8   0.1     0.0011   18.8   0.1    3.7  4  TPR_10    Tetratricopeptide repeat
     0.0013   18.8   0.1          5    7.6   0.0    3.5  3  TPR_8     Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.063   13.4   8.0        1.3    9.2   0.5    3.8  4  TPR_9     Tetratricopeptide repeat
       0.11   12.2   0.2       0.21   11.2   0.2    1.5  1  TPR_21    Tetratricopeptide repeat-like domain
       0.17   11.2   1.6       0.64    9.3   1.6    1.9  1  TPR_MalT  MalT-like TPR region
       0.22   12.2   2.2         17    6.3   0.2    3.6  3  TPR_6     Tetratricopeptide repeat
          2    9.0   3.9        2.9    8.5   0.2    3.0  2  TPR_17    Tetratricopeptide repeat
        3.4    7.9   5.1         24    5.3   0.1    3.3  3  TPR_7     Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> DUF4470  Domain of unknown function (DUF4470)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.5   0.1   4.3e-13   4.8e-10      16      94 ..     188     277 ..     156     280 .. 0.87

  Alignments for each domain:
  == domain 1  score: 39.5 bits;  conditional E-value: 4.3e-13
     DUF4470  16 edeendlniLllgsgDlRhvlktiasl.........kpssksrklditlndneaeivaRnlllLslllepd..dslgleeaaellleiwy 94 
                 ++ + +l+++l g gD+Rh+ + +a l         ++s  +r+ ++tlnd++ + +aRnl+lL ll e    +++++ e++e+++ ++y
  EEA21383.1 188 SNIDRNLSVFLGGIGDARHFYAQLAILgatermivhSTSPLQRRYNFTLNDSNCAAIARNLVLLVLLDELAclTDIPQAERTEIYTTVYY 277
                 344569****************************99668899**********************9999888998899************9 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.7   1.4e-06    0.0015       6      31 ..       8      33 ..       7      36 .. 0.90
   2 !   17.0   0.1   3.9e-06    0.0044       4      34 .]      41      71 ..      38      71 .. 0.94
   3 ?   -0.4   0.0       1.5   1.6e+03      11      27 ..      94     110 ..      92     113 .. 0.85
   4 ?    1.6   0.0      0.34   3.8e+02      14      25 ..     122     133 ..     120     135 .. 0.81

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 1.4e-06
       TPR_2  6 nlGlayyklgdyeeAleafekAleld 31
                ++G+a+yk+g++ eA++a+++A + +
  EEA21383.1  8 ERGNALYKRGHLTEAIKAYQAAARRA 33
                69********************9865 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 3.9e-06
       TPR_2  4 lynlGlayyklgdyeeAleafekAleldPnn 34
                + nl  ayy+ g++ e +++ ++Al+++ +n
  EEA21383.1 41 WSNLSAAYYEVGNLHESVQCAQRALAICQTN 71
                99************************99876 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 1.5
       TPR_2  11 yyklgdyeeAleafekA 27 
                 y++  +++ A++++ + 
  EEA21383.1  94 YLHTHQFDAARQWLHRL 110
                 89999******999875 PP

  == domain 4  score: 1.6 bits;  conditional E-value: 0.34
       TPR_2  14 lgdyeeAleafe 25 
                 l +y+eAl++ e
  EEA21383.1 122 LRQYQEALDHAE 133
                 789999999987 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.6     2e-05     0.023       7      27 ..       9      29 ..       7      34 .. 0.91
   2 !   11.7   0.0   0.00015      0.17       4      34 .]      41      71 ..      39      71 .. 0.91
   3 ?    1.1   0.0      0.36   4.1e+02      14      24 ..     122     132 ..     120     135 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 2e-05
                HHHHHHHTT-HHHHHHHHHHH CS
       TPR_1  7 lGnayfklgkydeAleyyekA 27
                +Gna++k g + eA+++y+ A
  EEA21383.1  9 RGNALYKRGHLTEAIKAYQAA 29
                8******************98 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 0.00015
                HHHHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1  4 lynlGnayfklgkydeAleyyekALelnPnn 34
                + nl +ay++ g++ e +++ ++AL ++ +n
  EEA21383.1 41 WSNLSAAYYEVGNLHESVQCAQRALAICQTN 71
                677778*********************9876 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.36
                 TT-HHHHHHHH CS
       TPR_1  14 lgkydeAleyy 24 
                 l +y+eAl++ 
  EEA21383.1 122 LRQYQEALDHA 132
                 78999999985 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.2   0.7   0.00017       0.2       1      52 [.      13      65 ..      13      69 .. 0.90
   2 ?    4.3   0.0      0.05        56      35      57 ..      94     116 ..      82     123 .. 0.84
   3 !    7.6   0.1    0.0047       5.2       5      33 ..     123     152 ..     121     154 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00017
      TPR_19  1 llaegdyaeAlalleqa.lqedpknaearllLAeallalgqldeAealLdalp 52
                l+++g ++eA++++++a   ++p++   + +L  a+++ g+l e  ++ ++++
  EEA21383.1 13 LYKRGHLTEAIKAYQAAaRRAEPDDYLPWSNLSAAYYEVGNLHESVQCAQRAL 65
                6899************84688*********************99999888765 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.05
      TPR_19  35 llalgqldeAealLdalpeedpd 57 
                 +l + q+d+A++ L +l + +  
  EEA21383.1  94 YLHTHQFDAARQWLHRLADVQSP 116
                 899*************9987665 PP

  == domain 3  score: 7.6 bits;  conditional E-value: 0.0047
      TPR_19   5 gdyaeAlalleqalqedpk..naearllLAe 33 
                  +y+eAl++ e ++q+ p+    +arl LAe
  EEA21383.1 123 RQYQEALDHAETVWQDFPDeeTYRARL-LAE 152
                 589999999999999999954444444.566 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   0.8   0.00016      0.18       6      38 ..       8      41 ..       5      46 .. 0.83
   2 ?    6.2   0.0     0.019        21       7      33 ..      44      70 ..      39      74 .. 0.86
   3 ?    4.2   0.1     0.084        94       9      32 ..      92     116 ..      89     123 .. 0.79
   4 ?    6.1   0.6     0.021        23      14      41 ..     122     149 ..     117     153 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 0.00016
      TPR_14  6 alaeallalGdpdeAiallrralal.aPddaeaw 38
                +++ al+ +G + eAi+++++a ++  Pdd   w
  EEA21383.1  8 ERGNALYKRGHLTEAIKAYQAAARRaEPDDYLPW 41
                7899*****************9886269987665 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.019
      TPR_14  7 laeallalGdpdeAiallrralalaPd 33
                l +a+++ G++ e++++++rala + +
  EEA21383.1 44 LSAAYYEVGNLHESVQCAQRALAICQT 70
                7789******************98755 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.084
      TPR_14   9 eallalGdpdeAiallrrala.laP 32 
                 + +l+  ++d+A++ l+r+ + + P
  EEA21383.1  92 RGYLHTHQFDAARQWLHRLADvQSP 116
                 67999*************8663455 PP

  == domain 4  score: 6.1 bits;  conditional E-value: 0.021
      TPR_14  14 lGdpdeAiallrralalaPddaeawlll 41 
                 l++++eA+++++ + +++Pd+++++ +l
  EEA21383.1 122 LRQYQEALDHAETVWQDFPDEETYRARL 149
                 789********************99555 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.7   2.1   1.1e-07   0.00012       1      42 []      10      52 ..      10      52 .. 0.93
   2 !    7.7   0.1    0.0026       2.9       3      29 ..      47      73 ..      46      75 .. 0.94
   3 ?   -3.1   0.1       5.8   6.4e+03      15      21 ..     123     129 ..     122     130 .. 0.76

  Alignments for each domain:
  == domain 1  score: 21.7 bits;  conditional E-value: 1.1e-07
      TPR_11  1 GdayyeqGkyeeAieaYkkAlk.ldPdnaeayynLGlayykqG 42
                G+a+y++G ++eAi+aY++A +   Pd+   ++nL +ayy+ G
  EEA21383.1 10 GNALYKRGHLTEAIKAYQAAARrAEPDDYLPWSNLSAAYYEVG 52
                9*****************9985389***************987 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0026
      TPR_11  3 ayyeqGkyeeAieaYkkAlkldPdnae 29
                ayye G++ e++++ ++Al+++++n +
  EEA21383.1 47 AYYEVGNLHESVQCAQRALAICQTNDN 73
                8**********************9975 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 5.8
      TPR_11  15 eaYkkAl 21 
                  +Y++Al
  EEA21383.1 123 RQYQEAL 129
                 5899998 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   4.1   1.6e-06    0.0018       8      76 ..       8      69 ..       5      70 .. 0.88
   2 !   15.5   0.1   1.4e-05     0.016       6      41 ..      41      76 ..      38      84 .. 0.84
   3 ?    0.3   0.1      0.79   8.9e+02      13      33 ..      94     114 ..      92     121 .. 0.85
   4 ?   -0.0   0.1         1   1.1e+03      17      28 ..     123     134 ..     117     151 .. 0.74

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 1.6e-06
      TPR_12  8 nlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76
                +++++l+++g ++eA++ +++a ++a+    pd +l      nL+ +y++ g++ e ++  ++alai++
  EEA21383.1  8 ERGNALYKRGHLTEAIKAYQAAARRAE----PDDYL---PWSNLSAAYYEVGNLHESVQCAQRALAICQ 69
                579*******************77773....66544...689*************************97 PP

  == domain 2  score: 15.5 bits;  conditional E-value: 1.4e-05
      TPR_12  6 lnnlaavlrrlgrydeAlellekaleiarrllGpdh 41
                ++nl a++++ g+++e+ ++ ++al+i++   +++ 
  EEA21383.1 41 WSNLSAAYYEVGNLHESVQCAQRALAICQTNDNGNG 76
                67999***********************98755554 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.79
      TPR_12  13 lrrlgrydeAlellekaleia 33 
                 +++  ++d A+++l++  +++
  EEA21383.1  94 YLHTHQFDAARQWLHRLADVQ 114
                 788999999999999998876 PP

  == domain 4  score: -0.0 bits;  conditional E-value: 1
      TPR_12  17 grydeAlellek 28 
                  +y+eAl++ e+
  EEA21383.1 123 RQYQEALDHAET 134
                 566666666665 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.1   2.2   7.9e-08   8.9e-05       3      63 ..       9      67 ..       7      72 .. 0.89
   2 ?    1.6   0.6      0.42   4.7e+02      10      54 ..     122     160 ..     117     162 .. 0.70

  Alignments for each domain:
  == domain 1  score: 23.1 bits;  conditional E-value: 7.9e-08
      TPR_16  3 laraalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraalra 63
                +++a++++g+ ++A++a++aa +r+  +Pd++  + +l  a+++ g+l e ++  ++al+ 
  EEA21383.1  9 RGNALYKRGHLTEAIKAYQAAARRA--EPDDYLPWSNLSAAYYEVGNLHESVQCAQRALAI 67
                79****************9999999..5**9999999999999999999999888888765 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.42
      TPR_16  10 agdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAa 54 
                 +++y++A+  +e++  ++p++        ++++++++++r+++A+
  EEA21383.1 122 LRQYQEALDHAETVWQDFPDEE------TYRARLLAELPRYQPAL 160
                 6778888888777777773333......46778888888888876 PP

>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   1.8     0.018        20       9      32 ..      10      33 ..       8      34 .. 0.90
   2 !   18.8   0.1   9.4e-07    0.0011       6      33 ..      42      69 ..      42      70 .. 0.96
   3 ?   -3.2   0.0       8.2   9.2e+03      14      27 ..      96     109 ..      93     111 .. 0.77
   4 ?    0.6   0.1      0.49   5.5e+02      15      29 ..     122     136 ..     120     138 .. 0.84

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.018
      TPR_10  9 analrqrgrydeAealleealair 32
                +nal++rg ++eA + ++ a ++ 
  EEA21383.1 10 GNALYKRGHLTEAIKAYQAAARRA 33
                89**************99998765 PP

  == domain 2  score: 18.8 bits;  conditional E-value: 9.4e-07
      TPR_10  6 nNLanalrqrgrydeAealleealairr 33
                +NL++a++++g+++e+++ +++alai++
  EEA21383.1 42 SNLSAAYYEVGNLHESVQCAQRALAICQ 69
                6*************************98 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 8.2
      TPR_10  14 qrgrydeAeallee 27 
                 ++ ++d+A+++l++
  EEA21383.1  96 HTHQFDAARQWLHR 109
                 5668999**99875 PP

  == domain 4  score: 0.6 bits;  conditional E-value: 0.49
      TPR_10  15 rgrydeAealleeal 29 
                 +++y+eA++++e + 
  EEA21383.1 122 LRQYQEALDHAETVW 136
                 789*******99876 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.6   0.1    0.0096        11       7      31 ..       9      33 ..       8      36 .. 0.88
   2 !    7.6   0.0    0.0045         5       4      32 ..      41      69 ..      40      71 .. 0.90
   3 ?   -0.5   0.0       1.7   1.9e+03      16      31 ..     836     851 ..     834     853 .. 0.82

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.0096
                HHHHHHHTT-HHHHHHHHHHHHHHH CS
       TPR_8  7 lgsiylklgdyeeAkeyyekaleld 31
                 g+++ k g + eA+++y+ a + +
  EEA21383.1  9 RGNALYKRGHLTEAIKAYQAAARRA 33
                589999*************998765 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0045
                HHHHHHHHHHTT-HHHHHHHHHHHHHHHH CS
       TPR_8  4 yynlgsiylklgdyeeAkeyyekaleldp 32
                + nl+ +y + g+++e++++ ++al + +
  EEA21383.1 41 WSNLSAAYYEVGNLHESVQCAQRALAICQ 69
                779999*******************9865 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 1.7
                 -HHHHHHHHHHHHHHH CS
       TPR_8  16 dyeeAkeyyekaleld 31 
                 d e +k  +e+++++d
  EEA21383.1 836 DDEVWKPIIEQCVSID 851
                 55678999*******9 PP

>> TPR_9  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.5    0.0012       1.3      33      60 ..       7      34 ..       5      37 .. 0.87
   2 ?    7.5   0.1    0.0041       4.6      25      60 ..      34      69 ..      32      83 .. 0.91
   3 ?   -0.2   0.5      0.99   1.1e+03      47      64 ..     117     134 ..     107     152 .. 0.80
   4 ?   -2.3   0.0       4.7   5.2e+03      35      49 ..     146     160 ..     137     161 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0012
       TPR_9 33 rdRGlllaqlGclsaAladLeaylalap 60
                r+RG +l+++G+l +A+++ +a+++ a+
  EEA21383.1  7 RERGNALYKRGHLTEAIKAYQAAARRAE 34
                9*********************996554 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0041
       TPR_9 25 aPddpeerrdRGlllaqlGclsaAladLeaylalap 60
                 Pdd   +     +++++G+l++ +++ +++la++ 
  EEA21383.1 34 EPDDYLPWSNLSAAYYEVGNLHESVQCAQRALAICQ 69
                699******************************997 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 0.99
       TPR_9  47 aAladLeaylalapdapd 64 
                  A++dL +y +  ++a++
  EEA21383.1 117 SAVDDLRQYQEALDHAET 134
                 699******977776654 PP

  == domain 4  score: -2.3 bits;  conditional E-value: 4.7
       TPR_9  35 RGlllaqlGclsaAl 49 
                 R++lla+l +++ Al
  EEA21383.1 146 RARLLAELPRYQPAL 160
                 99******9999996 PP

>> TPR_21  Tetratricopeptide repeat-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.2   0.00019      0.21     148     179 ..       5      36 ..       1      47 [. 0.86

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00019
      TPR_21 148 vaelrGDilvaqgkldeAraaYqaAlaaleek 179
                 ++  rG++l+++g+l+eA +aYqaA ++ e++
  EEA21383.1   5 QERERGNALYKRGHLTEAIKAYQAAARRAEPD 36 
                 56679********************9998876 PP

>> TPR_MalT  MalT-like TPR region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   1.6   0.00057      0.64      90     156 ..      13      72 ..       5     137 .. 0.57

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00057
    TPR_MalT  90 lvaqGrLheAletyeqalqlateqglqqlplvgfllvlladllyEwndLeeAeqhlqeGielleqle 156
                 l ++G+L eA++ y+ a + a+  +  ++             +yE ++L+e  q++q+++++++  +
  EEA21383.1  13 LYKRGHLTEAIKAYQAAARRAEPDDYLPWSNLS-------AAYYEVGNLHESVQCAQRALAICQTND 72 
                 556666666666666666655555544333222.......235666666666666666666666542 PP

>> TPR_6  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   0.2     0.015        17       6      29 ..       9      32 ..       8      37 .. 0.85
   2 ?   -1.0   0.0       3.3   3.7e+03       8      27 ..      46      65 ..      43      67 .. 0.78
   3 ?    3.2   0.0      0.15   1.7e+02      14      32 ..     123     141 ..     105     142 .. 0.86

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.015
                HHHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6  6 lalsyrklgdtdkAlealerlike 29
                ++ +++k g  ++A++a++   ++
  EEA21383.1  9 RGNALYKRGHLTEAIKAYQAAARR 32
                588999988**********98877 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 3.3
                HHHHHHHHHHHHHHHHHHHH CS
       TPR_6  8 lsyrklgdtdkAlealerli 27
                 +y++ g+  ++++  +r +
  EEA21383.1 46 AAYYEVGNLHESVQCAQRAL 65
                58999569999999999876 PP

  == domain 3  score: 3.2 bits;  conditional E-value: 0.15
                 HHHHHHHHHHHHHHHH-TT CS
       TPR_6  14 gdtdkAlealerlikeYPd 32 
                  ++++Al+  e + +++Pd
  EEA21383.1 123 RQYQEALDHAETVWQDFPD 141
                 69****************8 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.0       1.2   1.4e+03      18      34 .]       8      24 ..       7      24 .. 0.88
   2 ?    8.5   0.2    0.0026       2.9       2      33 ..      26      58 ..      25      59 .. 0.88

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 1.2
      TPR_17 18 nLAelllknGdlmtArq 34
                +++++l+k+G l +A++
  EEA21383.1  8 ERGNALYKRGHLTEAIK 24
                589********999985 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0026
      TPR_17  2 ylkalel.dPnnadaynnLAelllknGdlmtAr 33
                y+ a+++ +P++  ++ nL  ++++ G+l + +
  EEA21383.1 26 YQAAARRaEPDDYLPWSNLSAAYYEVGNLHESV 58
                899999978******************998765 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.3       0.1   1.2e+02       6      34 ..      10      36 ..       9      38 .. 0.81
   2 ?    5.3   0.1     0.021        24       2      30 ..      41      69 ..      41      75 .. 0.88
   3 ?   -2.4   0.1         6   6.7e+03      11      21 ..     121     131 ..     119     134 .. 0.80

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.1
       TPR_7  6 arlysrlGdyeeAielyeqsLaltkdped 34
                +++  ++G+  eAi+ y++  a ++++ d
  EEA21383.1 10 GNALYKRGHLTEAIKAYQA--AARRAEPD 36
                6777789************..88777654 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.021
       TPR_7  2 LlnLarlysrlGdyeeAielyeqsLaltk 30
                ++nL  +y ++G+  e +++ +++La++ 
  EEA21383.1 41 WSNLSAAYYEVGNLHESVQCAQRALAICQ 69
                579999*****************999985 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 6
       TPR_7  11 rlGdyeeAiel 21 
                 +l++y+eA+++
  EEA21383.1 121 DLRQYQEALDH 131
                 68999999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (878 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       357  (0.0199119); expected 358.6 (0.02)
Passed bias filter:                      338  (0.0188521); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              16  [number of targets reported over threshold]
# CPU time: 0.73u 0.28s 00:00:01.01 Elapsed: 00:00:00.53
# Mc/sec: 5016.12
//
Query:       EEA21384.1  [L=721]
Description: HLH transcription factor (PalcA), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.1e-13   49.1   1.6    5.7e-13   48.6   0.4    2.0  2  HLH       Helix-loop-helix DNA-binding domain
  ------ inclusion threshold ------
       0.12   11.9   3.7       0.15   11.6   0.0    2.3  2  BID       BH3 interacting domain (BID)


Domain annotation for each model (and alignments):
>> HLH  Helix-loop-helix DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0      0.51   4.6e+03      10      20 ..     454     464 ..     454     466 .. 0.83
   2 !   48.6   0.4   6.4e-17   5.7e-13       1      52 [.     590     672 ..     590     673 .. 0.93

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.51
                 HHHHHHHHHHH CS
         HLH  10 rrRRdriNsal 20 
                 r R  riN+a+
  EEA21384.1 454 RPRTSRINTAI 464
                 56999****98 PP

  == domain 2  score: 48.6 bits;  conditional E-value: 6.4e-17
                 HHHHHHHHHHHHHHHHHHHHHHHHHCST...............................CSTTSS-STHHHHHHHHHHHHHHH CS
         HLH   1 rraahnerErrRRdriNsaleeLrellP...............................slppskKlsKaeiLekAveYIkhL 52 
                 +r++h+++E+ RR+riN+al+e   llP                                  +++  sKa+++e+A++YIk L
  EEA21384.1 590 KRTNHKLAEQGRRNRINTALKEIEALLPpdfaqeraikegkeangvaknsdvkdtkdtkEKSTPPTISKASTVEMAIDYIKAL 672
                 79**************************************************99988654455559***************98 PP

>> BID  BH3 interacting domain (BID)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   1.6     0.086   7.8e+02      20      47 ..     108     135 ..      99     144 .. 0.76
   2 ?   11.6   0.0   1.7e-05      0.15     103     146 ..     582     625 ..     577     627 .. 0.93

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.086
                 HHHHHHTSXSSSHHHHHHHGGGXXXXXS CS
         BID  20 fgFLqscsdseFheeLeaLgkelpvkae 47 
                 f F q+ +++++h++L++ +++ + k  
  EEA21384.1 108 FHFSQEQQQQQYHQQLSQQQHQHQEKLV 135
                 8899999*********998887543333 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 1.7e-05
                 TSHHHHHHHHHCHCCCCCCCCHHHHHHHHHHHCTS--SSHCHHH CS
         BID 103 klvneLaaqfvneslseedrrkkLaaaleqvmqtipkDlekeka 146
                 +l ++L+++ +n++l+e +rr+++++al+++   +p D+++e+a
  EEA21384.1 582 TLAENLSSKRTNHKLAEQGRRNRINTALKEIEALLPPDFAQERA 625
                 67899*************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (721 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1885  (0.105137); expected 358.6 (0.02)
Passed bias filter:                      539  (0.030063); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.78u 0.31s 00:00:01.09 Elapsed: 00:00:00.51
# Mc/sec: 4253.33
//
Query:       EEA21385.1  [L=720]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.5e-13   48.1   0.0    9.4e-12   44.8   0.0    2.1  1  Septin        Septin
     0.0009   19.7   0.2     0.0026   18.2   0.0    1.8  2  AAA_16        AAA ATPase domain
  ------ inclusion threshold ------
      0.028   14.3   0.0      0.067   13.1   0.0    1.6  1  ATPase_2      ATPase domain predominantly from Archaea
      0.037   13.4   0.0        0.1   11.9   0.0    1.7  2  Mg_chelatase  Magnesium chelatase, subunit ChlI
      0.042   13.6   0.0      0.096   12.4   0.0    1.5  1  AAA_29        P-loop containing region of AAA domain
       0.05   14.1   0.4       0.18   12.3   0.4    2.1  1  ABC_tran      ABC transporter
      0.056   13.6   0.3       0.21   11.8   0.0    2.1  2  AAA_33        AAA domain
      0.066   12.3   0.0       0.12   11.4   0.0    1.3  1  T2SSE         Type II/IV secretion system protein
      0.073   12.8   0.1       0.21   11.4   0.0    1.7  2  ATP_bind_1    Conserved hypothetical ATP binding protein
       0.11   11.7   0.0       0.18   10.9   0.0    1.3  1  DUF815        Protein of unknown function (DUF815)
       0.12   12.8   0.0       0.27   11.7   0.0    1.6  1  AAA           ATPase family associated with various cellular 
       0.12   11.7   0.1        5.7    6.2   0.0    2.2  2  Gtr1_RagA     Gtr1/RagA G protein conserved region
       0.16   11.2   0.0       0.37   10.1   0.0    1.5  1  Zeta_toxin    Zeta toxin
       0.17   11.9   0.0        1.3    9.1   0.0    2.3  2  MMR_HSR1      50S ribosome-binding GTPase
       0.19   11.6   0.7        2.6    7.9   0.0    2.7  3  RsgA_GTPase   RsgA GTPase


Domain annotation for each model (and alignments):
>> Septin  Septin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.8   0.0   7.9e-15   9.4e-12       4     205 ..     216     448 ..     214     462 .. 0.80

  Alignments for each domain:
  == domain 1  score: 44.8 bits;  conditional E-value: 7.9e-15
                 EEEEEEEEBTTSSCCCCCCTTSSS.S----..................................--------.------S-EEEEEEEEETTCEEEEEE CS
      Septin   4 eftlmvvGesglGkttlintlfet.dliee..................................ekleease.kkkktveikkkkvvieedgvklnltv 66 
                  f ++v+G +g Gk++li+++++  d+i +                                  ++ + ++  +  ++ +i k+++   e  ++ nl  
  EEA21385.1 216 RFKILVAGPKGSGKSSLIRSIVQVcDDIVHvdlvensgqlehgrpysranfkksnaamiseiyaSTKPYPRWwSDLEDSRILKRRKNSGEVVLERNLCF 314
                 599*****************9985233333689999***********************988873334443346667888888999999999999**** PP

                 EE---BSSSSSH.HCCCHHHHHHHHHHHHHHHHHCTSS--..SS--....---EEEEEEEE-TTSSSS-HHHHHHHHHHTTTS-EEEEESSGGGS-HHH CS
      Septin  67 iDtpgfGdavdn.skswepiveyideqfeeylreesklkR..kkiv....DkRvHaclyfisPtghglkpldvelmkklsekvnliPviaKaDtltkeE 158
                 +Dt    +     +++ e+i++y+++q+++ + + s+     +++      + v  +ly+is         d+e++ kls+  n+iP+i+KaD l ++ 
  EEA21385.1 315 VDTTVSSNGTGQpDQNIEVIIQYMKQQLSRAIASISHPGSelQNMLggngGSQVDLILYLISE---DTLSYDIECILKLSDFSNVIPLISKADLLSESQ 410
                 ***9888877665899**************99876655442244432222689********75...44578**************************** PP

                 HHHHHHHHHHHHHHTT--------SSSS-SCCHHHHHHHHHHC-SEE CS
      Septin 159 lkefKkkireeleeeeikiyklpdeeededeeakelseklkeslPfa 205
                 ++++K+  ++++++++ +++++ d + +e +         +++ Pfa
  EEA21385.1 411 ITSLKSSFHSQIAQNSPQLFSFEDRNVSEGK---------QSQSPFA 448
                 *********************6666555533.........2344554 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0   2.1e-06    0.0026      27      71 ..     219     263 ..     213     356 .. 0.64
   2 ?   -3.4   0.2       9.1   1.1e+04      81     106 ..     562     587 ..     554     611 .. 0.60

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 2.1e-06
      AAA_16  27 vllsGesGvGKsslvrellralekdggif.lrgkcdqlesaipysa 71 
                 +l+ G++G+GKssl+r++  ++++d +++ l ++  qle ++pys 
  EEA21385.1 219 ILVAGPKGSGKSSLIRSIV-QVCDDIVHVdLVENSGQLEHGRPYSR 263
                 79*****************.89999666666666666666666533 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 9.1
      AAA_16  81 llrqlldeaesaeleawrekleeala 106
                  ++q ++++++  l+ w++ l+++l+
  EEA21385.1 562 DYTQHEEKLAQVRLAKWAADLQQSLQ 587
                 55566666666677777777777666 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   5.6e-05     0.067      23      48 ..     219     244 ..     214     425 .. 0.60

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 5.6e-05
    ATPase_2  23 yfiYGpegsGKtaLlkeiienledkd 48 
                 +++ Gp+gsGK++L++ i++  +d  
  EEA21385.1 219 ILVAGPKGSGKSSLIRSIVQVCDDIV 244
                 6789***************9986643 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   8.7e-05       0.1      19      57 ..     213     251 ..     210     274 .. 0.89
   2 ?   -3.0   0.0       3.3     4e+03      43      71 ..     394     421 ..     391     430 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 8.7e-05
  Mg_chelatase  19 aaGgHnlllvGppGsGKtmlakrlpsllpplseeealev 57 
                   a+G+ ++l++Gp GsGK+ l++ + ++  ++ + + +e 
    EEA21385.1 213 AIGRFKILVAGPKGSGKSSLIRSIVQVCDDIVHVDLVEN 251
                   78**********************999988888887776 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 3.3
  Mg_chelatase  43 psllpplseeealevakiasvagkkeeek 71 
                   ++++p +s+++ l  ++i+s+++ + +++
    EEA21385.1 394 SNVIPLISKADLLSESQITSLKS-SFHSQ 421
                   578999999**********9998.33333 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0     8e-05     0.096      25      42 ..     219     236 ..     209     241 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 8e-05
      AAA_29  25 tlltGpsGsGKSTllDAi 42 
                 +l++Gp GsGKS+l+ +i
  EEA21385.1 219 ILVAGPKGSGKSSLIRSI 236
                 79************9666 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.4   0.00015      0.18      14      43 ..     219     265 ..     216     455 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00015
                 EEEEESTTSSHHHHHHHHTTSS--........SEEEE.........E CS
                 xxxxxxxxxxxxxxxxxxxxxxxx........xxxxx.........x RF
    ABC_tran  14 vaivGenGaGKStLlkllagllkp........teGei.........l 43 
                 + + G+ G+GKS+L++ + +  ++        ++G++         +
  EEA21385.1 219 ILVAGPKGSGKSSLIRSIVQVCDDivhvdlveNSGQLehgrpysraN 265
                 5688**************99988644444433333334444444440 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   0.00017      0.21       2      38 ..     219     256 ..     219     326 .. 0.69
   2 ?   -1.7   0.3       2.4   2.9e+03      61      70 ..     516     525 ..     464     606 .. 0.58

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00017
      AAA_33   2 vllvGlpGsGKstlaerllkklg.avllssdtlrrrlf 38 
                 +l+ G++GsGKs l++++++  +  v+++  + + +l+
  EEA21385.1 219 ILVAGPKGSGKSSLIRSIVQVCDdIVHVDLVENSGQLE 256
                 6889***************9999888888666444444 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 2.4
      AAA_33  61 elarkalsag 70 
                 ++a k+++++
  EEA21385.1 516 DTAVKRQRSK 525
                 4444444333 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0    0.0001      0.12     129     166 ..     216     252 ..     210     269 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.0001
       T2SSE 129 rglilvsGgTgsGKttllyallkeinksderivtvEDp 166
                 r  ilv+G+ gsGK+ l+ ++++  ++   ++ +vE +
  EEA21385.1 216 RFKILVAGPKGSGKSSLIRSIVQVCDDI-VHVDLVENS 252
                 789*******************999888.777777765 PP

>> ATP_bind_1  Conserved hypothetical ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00017      0.21       1      26 [.     221     245 ..     221     250 .. 0.87
   2 ?   -2.5   0.0       3.1   3.7e+03     160     181 ..     397     418 ..     394     462 .. 0.54

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00017
  ATP_bind_1   1 vvGpaGsGKttfvgalseilelrgrs 26 
                 v+Gp GsGK++++++++++++++  +
  EEA21385.1 221 VAGPKGSGKSSLIRSIVQVCDDI-VH 245
                 89******************998.44 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 3.1
  ATP_bind_1 160 vvvlnkfDllkeklekeleffe 181
                 +  ++k+Dll+e++   l+   
  EEA21385.1 397 IPLISKADLLSESQITSLKSSF 418
                 6788999999966333333222 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00015      0.18      55      78 ..     218     241 ..     207     255 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00015
      DUF815  55 nvLLwGarGtGKSslvkallneya 78 
                 ++L+ G +G+GKSsl++++++ + 
  EEA21385.1 218 KILVAGPKGSGKSSLIRSIVQVCD 241
                 6899**************998665 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00022      0.27       1      28 [.     219     250 ..     219     281 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00022
                 EEEESSTTSSHHHHHHHHHHHHT....HEEEE CS
         AAA   1 vllyGppGtGKTllakavakelg....vefle 28 
                 +l+ Gp+G GK++l++++++ ++    v+++e
  EEA21385.1 219 ILVAGPKGSGKSSLIRSIVQVCDdivhVDLVE 250
                 699****************9874332255555 PP

>> Gtr1_RagA  Gtr1/RagA G protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   0.0    0.0048       5.7       1      19 [.     218     237 ..     218     257 .. 0.84
   2 ?    3.2   0.0     0.041        49     101     146 ..     383     428 ..     373     451 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0048
   Gtr1_RagA   1 kvLLmGksgsGKts.mrsii 19 
                 k+L  G++gsGK+s +rsi+
  EEA21385.1 218 KILVAGPKGSGKSSlIRSIV 237
                 89************446665 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.041
   Gtr1_RagA 101 ilealrqyspeakvfvlihKmDliqedereeifeerkeeireeiek 146
                  +e + + s   +v  li K Dl++e++ +++ ++ +++i +++ +
  EEA21385.1 383 DIECILKLSDFSNVIPLISKADLLSESQITSLKSSFHSQIAQNSPQ 428
                 577888899999999**************99999999999988764 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   0.00031      0.37      19      50 ..     219     247 ..     216     250 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00031
  Zeta_toxin  19 illgGqpGAGKselaellkdelerqgnvvrld 50 
                 il++G  G+GKs+l++ + +     +++v++d
  EEA21385.1 219 ILVAGPKGSGKSSLIRSIVQVC---DDIVHVD 247
                 89****************9997...7999987 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.0    0.0011       1.3       1      21 [.     218     238 ..     218     257 .. 0.85
   2 ?   -0.9   0.0       1.4   1.7e+03      43      58 ..     614     629 ..     587     657 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0011
                 EEEEEESTTSSHHHHHHHHHT CS
    MMR_HSR1   1 evaivGrpNvGKStLinaltg 21 
                 +++++G   +GKS+Li+++++
  EEA21385.1 218 KILVAGPKGSGKSSLIRSIVQ 238
                 5899**************987 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 1.4
                 ETTEEEEEEECGGCSS CS
    MMR_HSR1  43 lkgkeielvDtpGlie 58 
                 ++g+ + + DtpG+  
  EEA21385.1 614 IDGTLVPIQDTPGFPR 629
                 446667789****542 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   0.0    0.0022       2.6     102     122 ..     219     239 ..     209     265 .. 0.72
   2 ?    0.2   0.0      0.51   6.1e+02      49      72 ..     396     418 ..     366     437 .. 0.76
   3 ?   -1.5   0.1       1.7   2.1e+03     155     166 ..     621     632 ..     614     633 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0022
                  EEEECSTTSSHHHHHHHHCTT CS
  RsgA_GTPase 102 svlvGqSGvGKStLinallpe 122
                  ++++G+ G GKS+Li ++++ 
   EEA21385.1 219 ILVAGPKGSGKSSLIRSIVQV 239
                  4679************99884 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.51
                  EEEEEE-GGG--HHHHHHHHHHHH CS
  RsgA_GTPase  49 pvivlnKiDlleeeeeleelkeel 72 
                  ++ +++K+Dll+e++ +++lk+ +
   EEA21385.1 396 VIPLISKADLLSESQ-ITSLKSSF 418
                  344689*******99.66666554 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 1.7
                  EESS-SSSS--G CS
  RsgA_GTPase 155 liDtPGfreldl 166
                  + DtPGf ++d+
   EEA21385.1 621 IQDTPGFPRWDV 632
                  67*****98876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (720 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       579  (0.032294); expected 358.6 (0.02)
Passed bias filter:                      477  (0.0266049); expected 358.6 (0.02)
Passed Vit filter:                        84  (0.00468515); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.69u 0.31s 00:00:01.00 Elapsed: 00:00:00.46
# Mc/sec: 4731.89
//
Query:       EEA21386.1  [L=702]
Description: molecular chaperone and allergen Mod-E/Hsp90/Hsp1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
   1.3e-222  740.3  34.0   1.7e-222  739.9  34.0    1.0  1  HSP90        Hsp90 protein
    1.1e-15   58.2   0.1      2e-15   57.3   0.1    1.5  1  HATPase_c    Histidine kinase-, DNA gyrase B-, and HSP90-like
    2.6e-12   46.7   0.1      8e-12   45.2   0.1    1.9  1  HATPase_c_3  Histidine kinase-, DNA gyrase B-, and HSP90-like
  ------ inclusion threshold ------
       0.89    9.6   4.3       0.89    9.6   0.2    2.5  2  DUF1676      Protein of unknown function (DUF1676)


Domain annotation for each model (and alignments):
>> HSP90  Hsp90 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  739.9  34.0  3.8e-226  1.7e-222       1     511 [.     182     692 ..     182     699 .. 0.96

  Alignments for each domain:
  == domain 1  score: 739.9 bits;  conditional E-value: 3.8e-226
                 GGGSHHHHHHHHHHCCTTSSS-EEEEEEEEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....XXXXXXXXXXEEEEEEESXXSXGGGSXGGGSXH CS
       HSP90   1 eyleekklkelvkkySeFinfpiyllkekeeekeveeeeeeeeeeeeeeeeeakveeeeeeeee..kkktkkvketvkewellNkqkpiWlrkpkevte 97 
                 e+l+e+k+ke+vkk+SeFi++piyl+  ke+ekev+e+++ee++eee+ e+++k+ee+++eeee  +kktkk+ke ++e+e+lNk+kpiW+r+p+++t+
  EEA21386.1 182 EFLQESKIKEIVKKHSEFISYPIYLHIMKEVEKEVPEDDAEEAKEEEDGEKKPKIEEVDDEEEEkkEKKTKKIKEYKMEEEELNKTKPIWTRNPADITQ 280
                 89************************************9999999999********999888876789999**************************** PP

                 HHHHHHHHHTTTTTSXXSEEEEEEEXSSSXEEEEEEEXSSXXTTTTTTTTTSXXTTEEEEETTEEEESXXTTSSXGGGTTXEEEEEESSSXSSSTHHHH CS
       HSP90  98 eeYkeFYkslskdsedplavkhfsaegevefkaiLfvPkrapsdlfekykkkkknnikLYvrrVfitdefedllPkyLsFvkGvvdsddLPLNvsREtl 196
                 eeY++FYk+ls+d+ed+lavkhfs+eg++ef+aiLfvPkrap+dlfe+  kk+knnikLYvrrVfitd+++dl+P++LsF+kGvvds+dLPLN+sREtl
  EEA21386.1 281 EEYASFYKTLSNDWEDHLAVKHFSVEGQLEFRAILFVPKRAPFDLFET--KKTKNNIKLYVRRVFITDDASDLIPEWLSFIKGVVDSEDLPLNLSRETL 377
                 ***********************************************8..799********************************************** PP

                 HTCHHHHHHHHHHHHHHHHHHHTSXHHH..HHTHHHHHHHHHHHHHHHXGGGHHHHHTTXEEEETTEEEEEEEHHHHHHHSXTTXXEEEEEEXSSHHHH CS
       HSP90 197 qqnkilkvikkklvrKvlemlkklaeekeeykkfykefsknlklGiiedsanrkklakLlrfksskseeeltsLedYvermkekqksiYyiageskeev 295
                 qqnki+kvikk++v+K+le+++++ae++e ++kfy++fskn+klGi+ed++nr+ lakLlr++s+ks++e+tsL+dY++rm e+qk+iYyi+ges ++v
  EEA21386.1 378 QQNKIMKVIKKNIVKKTLELFNEIAEDREMFDKFYSAFSKNIKLGIHEDAQNRQTLAKLLRYNSTKSGDEMTSLTDYITRMPEHQKQIYYITGESLKAV 476
                 *************************************************************************************************** PP

                 HTSGGGHHHHHTTXXEEEEXSTTHHHHHHTXSEETTEEEEETTBSTXXXXXXHHHHHHHHHHHHHHHHHHHHHHHTTTTTESEEEEXSSXSSXSEEEEB CS
       HSP90 296 ekspflerlkkkgyevlylvdpiDeyvvqqlkeyegkklvnvakegleleeeeeekkkkeelkkkfeeltkllkevlkdkvekvkvserlvdsPcvlvt 394
                 +kspfl++lk+k++evl+lvdpiDey+++qlke++gkklv+++k+ +elee+eeek+++e+++k+fe+l+k lk++l+dkvekv+vs++lv +Pc++ t
  EEA21386.1 477 QKSPFLDTLKQKNFEVLFLVDPIDEYAFTQLKEFDGKKLVDITKD-FELEETEEEKAEREKEEKEFEPLAKSLKNILGDKVEKVVVSHKLVGAPCAIRT 574
                 ********************************************7.9**************************************************** PP

                 XTTSXXHHHHHHHHHHHHHHHSSTSSSSSXEEEEEXTTSHHHHHHHHHHHHTTT.XHHHHHHHHHHHHHHHHHTTXXXSXHHHHHHHHHHHHTTTTHXX CS
       HSP90 395 seygwsanmerimkaqalrdkskssymsskktleinprhpiikeLkkkveedke.deeakdlaellyetallesGfsledpasfakrierllklslgid 492
                 +++gwsanmerimkaqalrd+s+ssym+skkt+ei p+ piikeLkkkve+d e d+++k++++ll+et+ll sGf+++dpasfa+ri++l++l+l+++
  EEA21386.1 575 GQFGWSANMERIMKAQALRDTSMSSYMASKKTFEISPKSPIIKELKKKVEADGEnDRTVKSITQLLFETSLLVSGFTIDDPASFAERIHKLISLGLNVE 673
                 **************************************************9854389*****************************************7 PP

                 STTTTTTGGGXGGGXXXXX CS
       HSP90 493 edeeveeeeeveeeeeeee 511
                 ed e++ee++ ee++++e+
  EEA21386.1 674 EDVEAAEEKDGEETAAAEA 692
                 7777777766665554444 PP

>> HATPase_c  Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.3   0.1   4.4e-19     2e-15       1     111 [.      25     179 ..      25     180 .. 0.81

  Alignments for each domain:
  == domain 1  score: 57.3 bits;  conditional E-value: 4.4e-19
                 EHHHHHHHHHHHHHHHHHHH..........HSTTTEEEEEEEEEETEEEEEEEESSSSSTTHHHT.......GTCS.TTCH.....HCSTCHTSTSSSH CS
   HATPase_c   1 gdekrLrqiisnlvdNavkf..........atkageieveikaseddlvisveDnGiGipkedlk.......klfe.kfsq.....ddstkrggggtGl 76 
                 ++e++Lr++isn +d+++k+            +++++++ i++++++++i+++D+GiG++k+dl        ++++  f++     +d +++g++g+G+
  EEA21386.1  25 NKEIFLRELISNCSDALDKIryealsdpskLDTGKDLRIDITPDKENKTITIRDTGIGMTKADLInnlgtiaRSGTkQFMEaltagADISMIGQFGVGF 123
                 5899****************99988877532267788999998789**************************999999999998566666666666665 PP

                 .HHHHH.............HH.HHH.HTTTEEEEEEET.....TTEEEEEEEEESS CS
   HATPase_c  77 .Glsiv.............kk.lve.lmgGeiwvesep.....grGttftftlple 111
                  ++++v             ++ ++e   gG+++++++      grGt+++++l+ e
  EEA21386.1 124 ySAYLVadkvtviskhnddEQyIWEsSAGGTFTLTQDTegeplGRGTKMILHLKDE 179
                 555555899999999999866688888999999944444566999********987 PP

>> HATPase_c_3  Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.2   0.1   1.8e-15     8e-12       1      99 [.      23     144 ..      23     153 .. 0.84

  Alignments for each domain:
  == domain 1  score: 45.2 bits;  conditional E-value: 1.8e-15
  HATPase_c_3   1 ysl.ekAlaelvdNsldAdaen..................vkievnknrgktgeivieDdGkGmseeelknal.rlatsskeakr.......kstslG 71 
                  ys+ e+ l el+ N+ dA  +                   ++i+ +k+   +++i+i+D G Gm++++l+n l ++a+s +++         +   +G
   EEA21386.1  23 YSNkEIFLRELISNCSDALDKIryealsdpskldtgkdlrIDITPDKE---NKTITIRDTGIGMTKADLINNLgTIARSGTKQFMealtagaDISMIG 117
                  566688899*********88878999************8888888776...58******************7747999988855434444335666** PP

  HATPase_c_3  72 kkGiGlklAslslgkkltvitkkegess 99 
                  ++G+G + ++  +++k+tvi+k++++++
   EEA21386.1 118 QFGVG-FYSAYLVADKVTVISKHNDDEQ 144
                  *****.999999***********98765 PP

>> DUF1676  Protein of unknown function (DUF1676)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.5      0.13   5.7e+02      97     121 ..     218     254 ..     129     260 .. 0.62
   2 ?    9.6   0.2    0.0002      0.89      23      83 ..     511     565 ..     499     568 .. 0.61

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.13
     DUF1676  97 eesisrsleedne............egRkkk.kkkkkl 121
                 e++ ++++ee+++            e   kk kk kk 
  EEA21386.1 218 EDDAEEAKEEEDGekkpkieevddeEE-EKKeKKTKKI 254
                 333322222222234444444444322.2332444444 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.0002
     DUF1676  23 ldkdeielvdgvslvrneeaasasskeeeeelsreeeeare...eelekllleklerflkshsl 83 
                   k+ ++++ + +l  +ee++       e+e++++e    e   ++l+++l +k+e+++ sh+l
  EEA21386.1 511 DGKKLVDITKDFELEETEEEK------AEREKEEKEF---EplaKSLKNILGDKVEKVVVSHKL 565
                 444444455555555544442......2222223333...25559*****************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (702 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1931  (0.107703); expected 358.6 (0.02)
Passed bias filter:                      525  (0.0292822); expected 358.6 (0.02)
Passed Vit filter:                        73  (0.00407162); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.71u 0.30s 00:00:01.01 Elapsed: 00:00:00.43
# Mc/sec: 4857.18
//
Query:       EEA21387.1  [L=549]
Description: NTF2 and RRM domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.5e-26   91.8   0.3      8e-26   91.0   0.3    1.4  1  NTF2      Nuclear transport factor 2 (NTF2) domain
    4.7e-08   32.7   0.0    8.2e-08   32.0   0.0    1.4  1  RRM_1     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom


Domain annotation for each model (and alignments):
>> NTF2  Nuclear transport factor 2 (NTF2) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.0   0.3   8.9e-30     8e-26       1     120 []      63     178 ..      63     178 .. 0.90

  Alignments for each domain:
  == domain 1  score: 91.0 bits;  conditional E-value: 8.9e-30
                 HHHHHHHHHHHHHHHHGGGGGGGGEEEEEEEEEETTE...EEEESHHHHHHHHHHSSCSCEEEEEEEEEEEETSEGGGCEEEEEEEEEEEETTSCCEEE CS
        NTF2   1 vakafvqqYYaaldagdregllalyaadaslltpegs...spvkgreaIteffrslpftrielkittvdaqpdeaslstgvlvmvtGelkvddfkkrrk 96 
                 v++ fv+qYY+++ + ++e+l+ +y++   +++ ++      v+g++aI++++++l+f ++++++ +vd+q   as  + +lv v Ge ++  ++  rk
  EEA21387.1  63 VGWYFVEQYYTTMSR-NPEKLHLFYSRRSQFVSGDEAenvPVVVGQKAINDKIKELDFHDCKVRVLNVDSQ---AS-FDNILVAVIGEISNRSKP-SRK 155
                 6789***********.*********6555555555557877899***************************...65.599**************5.9** PP

                 EEEEEEEEEETTTEEEEEEEEEEE CS
        NTF2  97 fsqtfilapqsnkgyfvlnDifrl 120
                 f+qtf+la+q  +gy+vlnDifr+
  EEA21387.1 156 FTQTFVLAQQP-NGYYVLNDIFRY 178
                 **********9.9**********8 PP

>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.0   0.0   9.1e-12   8.2e-08       2      63 ..     414     469 ..     413     476 .. 0.91

  Alignments for each domain:
  == domain 1  score: 32.0 bits;  conditional E-value: 9.1e-12
                 EEESETTTSSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEE CS
       RRM_1   2 fVgnLppdvteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkk 63 
                 +++n+++ v+ + L++++s fG+ +++++ r     s+++afV+F+++ + ++A++  n  +
  EEA21387.1 414 YIKNVTEKVDASLLRTVLSRFGKLTHFDVNR-----SRNCAFVDFADQTAYNAAVA-ANPHQ 469
                 9******************************.....8******************9.55555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (549 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1091  (0.0608511); expected 358.6 (0.02)
Passed bias filter:                      419  (0.02337); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.73u 0.36s 00:00:01.08 Elapsed: 00:00:00.52
# Mc/sec: 3182.31
//
Query:       EEA21388.1  [L=120]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (120 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       279  (0.0155614); expected 358.6 (0.02)
Passed bias filter:                      217  (0.0121033); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.25s 00:00:00.63 Elapsed: 00:00:00.43
# Mc/sec: 846.20
//
Query:       EEA21389.1  [L=187]
Description: glutathione-dependent formaldehyde-activating enzyme, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.5e-10   40.6   0.3    2.5e-10   40.6   0.3    1.5  2  GFA       Glutathione-dependent formaldehyde-activating enzym


Domain annotation for each model (and alignments):
>> GFA  Glutathione-dependent formaldehyde-activating enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.5   1.0         1   1.8e+04       3       5 ..      27      29 ..      26      31 .. 0.79
   2 !   40.6   0.3   1.4e-14   2.5e-10       2      92 ..      47     138 ..      46     139 .. 0.85

  Alignments for each domain:
  == domain 1  score: -4.5 bits;  conditional E-value: 1
         GFA  3 ChC 5 
                ChC
  EEA21389.1 27 CHC 29
                9*9 PP

  == domain 2  score: 40.6 bits;  conditional E-value: 1.4e-14
         GFA   2 lChCsdCrkasgsaftanavvkaealellegelkeykktadsgnkvtrsfCpeCgsplyse...esaapevvivrvGtlddpeklkpeaeiftk 92 
                 +C Cs+C k +gs f+++ v++++++++++ + k  +   ds+  ++r+ C++Cg++++ +   e++ +++ +v++ + d++   +p+++ f++
  EEA21389.1  47 ACGCSKCWKPAGSLFSVVGVIPTDKVSVTANSDK-LT-IVDSEAVIQRNACSQCGVHMFGRihkEHPFKGLDFVHAELSDTKGWQEPQFAAFVS 138
                 7**************************8887333.33.2579*****************98766677778999999999999999999988886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (187 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       498  (0.0277762); expected 358.6 (0.02)
Passed bias filter:                      314  (0.0175135); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.49
# Mc/sec: 1155.21
//
Query:       EEA21390.1  [L=213]
Description: hypothetical protein PMAA_052000 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.15   11.7   0.0       0.22   11.1   0.0    1.2  1  Xylo_C    Xylosyltransferase C terminal


Domain annotation for each model (and alignments):
>> Xylo_C  Xylosyltransferase C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   1.2e-05      0.22      49     120 ..      50     121 ..      28     136 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 1.2e-05
      Xylo_C  49 kklaeslkekaleeslriepkgvlevtlyfeddrFqGyLvrfeakeekskkeetlEtwvspkkslklakkts 120
                 k++++s ++ +++e+ + + ++  +++l f++d+F G ++ + ++ ++s+ +++ E  +   +++++++  s
  EEA21390.1  50 KAANASSTKASNSEDTKKNGAKEEQANLVFDSDEFCGSVIDTVMSAAASTGDLKHEFVLDSGATVHITNDRS 121
                 334444455545566666666669*********************999999999999988888887777654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (213 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1005  (0.0560544); expected 358.6 (0.02)
Passed bias filter:                      577  (0.0321825); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.35s 00:00:00.98 Elapsed: 00:00:00.57
# Mc/sec: 1123.83
//
Query:       EEA21391.1  [L=612]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.2e-10   39.1   0.0    8.4e-10   38.1   0.0    1.5  1  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.1   0.0   4.7e-14   8.4e-10       4     156 ..     114     265 ..     111     268 .. 0.66

  Alignments for each domain:
  == domain 1  score: 38.1 bits;  conditional E-value: 4.7e-14
  Fungal_trans   4 ffsnfhpqfpilhkpsflpkt.ssenssksayaspllllailalGalfsesetkes..nssltses.qefiafpl.raeilihedfsspssslwilq 95 
                   +f   +p +  +h   f +   +++ ++ s++++ +l++a+++lGa+ +  ++ e   +s ++ e+ q  + ++  +  +l+++   s +   ++l+
    EEA21391.1 114 YFNSNSPALRKFHLVIFKEIGkFWDDPHGSPISFLALIYAVMCLGAFVALGADEEHpnSSGTSPEMvQ-IYRGCCaQCLALSNYAKHSGP---YTLE 206
                   5555555554444444444336677789******************9864333333002222223332.333333133444434444444...5666 PP

  Fungal_trans  96 sLlll..elyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlw 156
                   ++ll+  + + +  +++ ++++++gvavrla ++gLhr+p++       + ++ + e+rrR+w
    EEA21391.1 207 TFLLYieADFVLSKGNQMSCYLIVGVAVRLAFRMGLHRDPNNMVG----TITPYQGEIRRRIW 265
                   443332378999999***************************995....599999******** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (612 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       407  (0.0227007); expected 358.6 (0.02)
Passed bias filter:                      385  (0.0214736); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.66u 0.31s 00:00:00.97 Elapsed: 00:00:00.51
# Mc/sec: 3623.69
//
Query:       EEA21392.1  [L=332]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.5e-21   76.7   0.1    1.8e-17   63.4   0.1    2.2  2  adh_short     short chain dehydrogenase
    1.5e-15   57.4   0.0    1.1e-12   48.0   0.0    2.1  2  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
    1.4e-05   25.0   0.1    4.9e-05   23.3   0.1    1.8  2  KR            KR domain


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.4   0.1     3e-21   1.8e-17       2     125 ..      27     155 ..      26     188 .. 0.86
   2 !   11.3   0.0   2.8e-05      0.17     141     190 ..     200     249 ..     193     253 .. 0.89

  Alignments for each domain:
  == domain 1  score: 63.4 bits;  conditional E-value: 3e-21
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT..TSE....EEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGG CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee..gak....alaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfs 94 
                 v ++tGa+sG+G ++ak l+ +G +++v++rs+ ++e +++++k++  g+k    + ++ +D++d + ++++ve+ + +  +ldvLvnNAG+  ++p+ 
  EEA21392.1  27 VFIITGAASGVGFELAKILYVAGGTIYVAARSATRCEGAIEKIKDQtrGKKaegvLKPMILDLADLRTIKRAVEDFQRQETRLDVLVNNAGV-MNTPVG 124
                 679*****************************************99986663344567789*******************************.677777 PP

                 GCSHHHHHHHHHHHTHHHHHHHHHHHHHHHH CS
   adh_short  95 elseeewervievNltgvflltravlpamlk 125
                 +   +  +  +++N +g++lltr++ p +++
  EEA21392.1 125 SKGTQGHDLEMATNCVGPYLLTRLLEPILIQ 155
                 7777889999**************9999883 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 2.8e-05
                 SB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHH CS
   adh_short 141 vpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakel 190
                 +++  +  Y  +K + + l+ ++a+ l +++i  ++v+PGl++T+++++ 
  EEA21392.1 200 MKSQPGDNYMQTKIGGTWLAAEFANRLGSKEILSVSVHPGLMRTELQRNM 249
                 56666778999***********************************9876 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.0   0.0   1.9e-16   1.1e-12       1     119 [.      32     156 ..      32     183 .. 0.91
   2 !    7.5   0.0   0.00044       2.6     140     183 ..     207     250 ..     194     264 .. 0.86

  Alignments for each domain:
  == domain 1  score: 48.0 bits;  conditional E-value: 1.9e-16
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGH.HHHHHHHHHHTTSE....E...EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGG CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneea.kkrveelaeelgae....v...lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfle 89 
                   Gaasg+G+++Ak l  +G ++ ++ ++  + + ++e++++++  +    v   + +D +d  +++++ve+ +++  +lD+lvnnag++++   p+ +
    EEA21392.1  32 GAASGVGFELAKILYVAGGTIYVAARSATRcEGAIEKIKDQTRGKkaegVlkpMILDLADLRTIKRAVEDFQRQETRLDVLVNNAGVMNT---PVGS 125
                   9***************************************998443335589999**********************************9...9999 PP

                   H-HHHHHHHHHHHTHHHHHHHHHHHH.HCTS CS
  adh_short_C2  90 tsreefdraldvnlyslfllakaalp.lmke 119
                      ++ d  +++n+ + +ll++ ++p l++ 
    EEA21392.1 126 KGTQGHDLEMATNCVGPYLLTRLLEPiLIQT 156
                   999***********************54444 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.00044
                   HHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGST CS
  adh_short_C2 140 aygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgik 183
                    y+ +K +   l+  +A+ lg+k+i   +v+pg+++T+++++++
    EEA21392.1 207 NYMQTKIGGTWLAAEFANRLGSKEILSVSVHPGLMRTELQRNMT 250
                   68889999999999************************999876 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.3   0.1   8.1e-09   4.9e-05       2      94 ..      27     121 ..      26     151 .. 0.80
   2 ?   -1.3   0.0      0.28   1.7e+03     104     143 ..     204     243 ..     199     255 .. 0.67

  Alignments for each domain:
  == domain 1  score: 23.3 bits;  conditional E-value: 8.1e-09
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHH.HHTT-..EEEE----TT-HHHHHHHHHHHHHHSS---EEEE------- CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliael.ealga..evevvaaDvsdkdavealleeikaeeppikGvihaAgvlrd 94 
                 +++itG++ g+G ela+ l+  g  ++ + +Rsa+  e + ++i+   + + a    + + +D++d   +++++e+++++e ++   ++ Agv+++
  EEA21392.1  27 VFIITGAASGVGFELAKILYVAGG-TIYVAARSATRCEGAIEKIKDQtRGKKAegVLKPMILDLADLRTIKRAVEDFQRQETRLDVLVNNAGVMNT 121
                 579*****************9996.699999997555555554443302233333588999********************************976 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.28
                 HHHHHHTTTTHHHHHHHHHTTTS--SEEEEEEEHHHHH-- CS
          KR 104 dleqvlapKvkGawnLhelledesldffvlfSSiagllgs 143
                   ++ ++ K+ G+w   e+ ++   + ++ +S   gl+ +
  EEA21392.1 204 PGDNYMQTKIGGTWLAAEFANRLGSKEILSVSVHPGLMRT 243
                 5577899999999988887776555555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (332 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       439  (0.0244855); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2353.59
//
Query:       EEA21393.1  [L=502]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.6e-05   24.3   0.9        1.1    9.8   0.0    3.8  3  TPR_17    Tetratricopeptide repeat
    0.00036   20.2   0.6       0.43   10.5   0.2    3.7  4  TPR_1     Tetratricopeptide repeat
     0.0054   16.8   8.0       0.25   11.5   0.2    4.8  4  TPR_2     Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.011   15.9   3.0       0.51   10.7   0.1    4.0  4  TPR_8     Tetratricopeptide repeat
      0.025   14.3   8.1       0.55   10.0   0.0    4.9  5  TPR_11    TPR repeat
      0.095   12.6   0.9         10    6.2   0.9    3.8  2  TPR_10    Tetratricopeptide repeat
       0.17   12.4   2.6         28    5.3   0.0    4.0  4  TPR_19    Tetratricopeptide repeat
       0.18   12.1   9.7        8.2    6.8   1.0    4.7  4  TPR_12    Tetratricopeptide repeat
       0.77   10.5   3.8         92    4.0   0.0    4.7  4  TPR_6     Tetratricopeptide repeat
       0.79   10.7  12.2        3.4    8.8   0.2    5.5  5  TPR_14    Tetratricopeptide repeat
        1.1    9.7   4.2         15    6.1   0.2    3.5  3  DALR_2    DALR domain
        1.1    9.7  11.0       0.18   12.3   1.7    3.3  3  FlgN      FlgN protein


Domain annotation for each model (and alignments):
>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.8   0.0   0.00076       1.1       2      28 ..      68      94 ..      67     100 .. 0.87
   2 !    9.5   0.0   0.00091       1.4       4      24 ..     119     139 ..     117     160 .. 0.78
   3 ?    0.7   0.1       0.6   8.9e+02      11      32 ..     426     448 ..     419     450 .. 0.71

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00076
      TPR_17  2 ylkaleldPnnadaynnLAelllknGd 28
                y + l++ P+++d+ +n+A++++++ +
  EEA21393.1 68 YDNGLAKFPTSFDLAYNKARVQYEITQ 94
                9999****************9887655 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00091
      TPR_17   4 kaleldPnnadaynnLAelll 24 
                  al ld +nad+++n A++l 
  EEA21393.1 119 HALVLDQDNADVLFNTAQVLT 139
                 68999*************997 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 0.6
      TPR_17  11 nnadaynnLAelll.knGdlmtA 32 
                 +na  y+  A +l+ + Gd+++ 
  EEA21393.1 426 KNAQTYYRGAAALArRDGDSEQE 448
                 47777888888776455888775 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.0     0.011        16      14      31 ..      51      68 ..      49      70 .. 0.89
   2 ?   -2.6   0.0         4     6e+03      20      34 .]     113     127 ..     113     127 .. 0.87
   3 !   10.5   0.2   0.00028      0.43      14      31 ..     153     170 ..     151     173 .. 0.88
   4 ?   -3.2   0.0       6.1   9.1e+03      19      28 ..     339     348 ..     338     349 .. 0.85

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.011
                TT-HHHHHHHHHHHHHHS CS
       TPR_1 14 lgkydeAleyyekALeln 31
                 g++ +A  ++ +A+e++
  EEA21393.1 51 AGDPVKAMRFFMRAIEIY 68
                59999***********97 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 4
                 HHHHHHHHHHHSTTH CS
       TPR_1  20 AleyyekALelnPnn 34 
                 Al+  + AL l+ +n
  EEA21393.1 113 ALQSHRHALVLDQDN 127
                 7888899****9987 PP

  == domain 3  score: 10.5 bits;  conditional E-value: 0.00028
                 TT-HHHHHHHHHHHHHHS CS
       TPR_1  14 lgkydeAleyyekALeln 31 
                  g+ +eA +y ++ALel 
  EEA21393.1 153 EGRIQEAMKYLNEALELF 170
                 699*************96 PP

  == domain 4  score: -3.2 bits;  conditional E-value: 6.1
                 HHHHHHHHHH CS
       TPR_1  19 eAleyyekAL 28 
                 eAl  ++ A+
  EEA21393.1 339 EALTSFNSAI 348
                 8999999998 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.017        25      13      32 ..      50      69 ..      48      70 .. 0.90
   2 !   11.5   0.2   0.00017      0.25      13      31 ..     152     170 ..     150     173 .. 0.88
   3 ?    0.6   0.0      0.54   8.1e+02      18      32 ..     338     352 ..     334     354 .. 0.89
   4 ?   -2.6   0.2       5.7   8.5e+03      20      31 ..     428     439 ..     426     442 .. 0.56

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.017
       TPR_2 13 klgdyeeAleafekAleldP 32
                ++gd+ +A ++f +A+e++ 
  EEA21393.1 50 RAGDPVKAMRFFMRAIEIYD 69
                789**************986 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 0.00017
       TPR_2  13 klgdyeeAleafekAleld 31 
                 + g+ +eA +++++Alel 
  EEA21393.1 152 NEGRIQEAMKYLNEALELF 170
                 679**************97 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.54
       TPR_2  18 eeAleafekAleldP 32 
                 +eAl  f+ A++ +P
  EEA21393.1 338 AEALTSFNSAIADNP 352
                 89*********9998 PP

  == domain 4  score: -2.6 bits;  conditional E-value: 5.7
       TPR_2  20 AleafekAleld 31 
                 A  +++ A +l+
  EEA21393.1 428 AQTYYRGAAALA 439
                 555666665555 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0      0.13     2e+02      15      31 ..      52      68 ..      47      70 .. 0.82
   2 ?   10.7   0.1   0.00034      0.51      13      30 ..     152     169 ..     150     173 .. 0.89
   3 ?   -2.7   0.1       6.7     1e+04      19      33 ..     373     387 ..     371     388 .. 0.80
   4 ?   -1.1   0.0         2     3e+03      18      32 ..     426     440 ..     425     442 .. 0.80

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.13
                T-HHHHHHHHHHHHHHH CS
       TPR_8 15 gdyeeAkeyyekaleld 31
                gd  +A+ ++++a+e+ 
  EEA21393.1 52 GDPVKAMRFFMRAIEIY 68
                66669**********96 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 0.00034
                 HTT-HHHHHHHHHHHHHH CS
       TPR_8  13 klgdyeeAkeyyekalel 30 
                 + g+++eA++y+++alel
  EEA21393.1 152 NEGRIQEAMKYLNEALEL 169
                 679*************98 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 6.7
                 HHHHHHHHHHHHHHH CS
       TPR_8  19 eAkeyyekaleldpd 33 
                 +A e++  a +l+ +
  EEA21393.1 373 AALEALTTASKLASA 387
                 789999999999865 PP

  == domain 4  score: -1.1 bits;  conditional E-value: 2
                 HHHHHHHHHHHHHHH CS
       TPR_8  18 eeAkeyyekaleldp 32 
                 ++A+ yy+ a  l++
  EEA21393.1 426 KNAQTYYRGAAALAR 440
                 799****99987776 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.1      0.58   8.7e+02      13      40 ..      64      91 ..      63      92 .. 0.84
   2 ?   10.0   0.0   0.00037      0.55      13      38 ..     113     138 ..     113     141 .. 0.88
   3 ?    2.9   0.1     0.058        87       7      23 ..     153     169 ..     150     171 .. 0.93
   4 ?    1.1   0.0      0.21   3.2e+02      12      25 ..     339     352 ..     338     353 .. 0.92
   5 ?   -0.9   0.1      0.91   1.4e+03      10      26 ..     371     387 ..     369     400 .. 0.71

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.58
      TPR_11 13 AieaYkkAlkldPdnaeayynLGlayyk 40
                Aie Y + l+  P++ ++ yn + ++y+
  EEA21393.1 64 AIEIYDNGLAKFPTSFDLAYNKARVQYE 91
                8888999999999999999998888875 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00037
      TPR_11  13 AieaYkkAlkldPdnaeayynLGlay 38 
                 A+++ + Al ld+dna++++n ++++
  EEA21393.1 113 ALQSHRHALVLDQDNADVLFNTAQVL 138
                 7778889**************99886 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.058
      TPR_11   7 qGkyeeAieaYkkAlkl 23 
                  G++ eA++ +++Al+l
  EEA21393.1 153 EGRIQEAMKYLNEALEL 169
                 69*************98 PP

  == domain 4  score: 1.1 bits;  conditional E-value: 0.21
      TPR_11  12 eAieaYkkAlkldP 25 
                 eA+++++ A++ +P
  EEA21393.1 339 EALTSFNSAIADNP 352
                 9*********9998 PP

  == domain 5  score: -0.9 bits;  conditional E-value: 0.91
      TPR_11  10 yeeAieaYkkAlkldPd 26 
                 +++A+ea+ +A kl + 
  EEA21393.1 371 LTAALEALTTASKLASA 387
                 68999999999998655 PP

>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0      0.93   1.4e+03      15      32 ..      51      68 ..      49      70 .. 0.86
   2 ?    6.2   0.9    0.0068        10      16      34 ..     154     172 ..     134     178 .. 0.78

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.93
      TPR_10 15 rgrydeAealleealair 32
                 g+  +A++++ +a++i+
  EEA21393.1 51 AGDPVKAMRFFMRAIEIY 68
                678889**********98 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.0068
      TPR_10  16 grydeAealleealairrr 34 
                 gr +eA+++l eal++ +r
  EEA21393.1 154 GRIQEAMKYLNEALELFQR 172
                 8889999999999988444 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.019        28       9      37 ..      63      91 ..      49      97 .. 0.80
   2 ?   -2.7   0.1       5.8   8.6e+03      17      37 ..     120     140 ..     113     149 .. 0.66
   3 ?    4.3   0.0     0.038        57       4      54 ..     153     169 ..     150     180 .. 0.64
   4 ?   -2.1   0.1       3.8   5.7e+03       7      20 ..     371     384 ..     369     391 .. 0.72

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.019
      TPR_19  9 eAlalleqalqedpknaearllLAealla 37
                +A++++ + l++ p + +++++ A+++++
  EEA21393.1 63 RAIEIYDNGLAKFPTSFDLAYNKARVQYE 91
                468888888899999**********9986 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 5.8
      TPR_19  17 alqedpknaearllLAealla 37 
                 al  d +na+++ + A++l +
  EEA21393.1 120 ALVLDQDNADVLFNTAQVLTS 140
                 555567777777777776654 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.038
      TPR_19   4 egdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpee 54 
                 eg+ +eA+++l +al+                                   
  EEA21393.1 153 EGRIQEAMKYLNEALE----------------------------------L 169
                 4666666666666655..................................4 PP

  == domain 4  score: -2.1 bits;  conditional E-value: 3.8
      TPR_19   7 yaeAlalleqalqe 20 
                 +++Al++l+ a + 
  EEA21393.1 371 LTAALEALTTASKL 384
                 78899999888655 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.0     0.052        78      56      76 ..      49      69 ..      44      70 .. 0.84
   2 ?    6.8   1.0    0.0055       8.2      59      76 ..     154     171 ..     111     172 .. 0.73
   3 ?   -2.7   0.1         5   7.5e+03      22      39 ..     370     387 ..     369     400 .. 0.62
   4 ?    2.6   0.5      0.11   1.7e+02      21      55 ..     427     461 ..     424     467 .. 0.77

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.052
      TPR_12 56 ralgryeeAlelleealaiae 76
                +++g++ +A +++ +a++i+ 
  EEA21393.1 49 WRAGDPVKAMRFFMRAIEIYD 69
                688999999999999999986 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.0055
      TPR_12  59 gryeeAlelleealaiae 76 
                 gr +eA ++l+eal++++
  EEA21393.1 154 GRIQEAMKYLNEALELFQ 171
                 556666666666666654 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 5
      TPR_12  22 AlellekaleiarrllGp 39 
                 Al+   +al  a++l   
  EEA21393.1 370 ALTAALEALTTASKLASA 387
                 555555666666555444 PP

  == domain 4  score: 2.6 bits;  conditional E-value: 0.11
      TPR_12  21 eAlellekaleiarrllGpdhpltattlrnLgrly 55 
                  A+++++ a ++arr  + + + + ++  +L+ ++
  EEA21393.1 427 NAQTYYRGAAALARRDGDSEQEKEGSCKEALAAAL 461
                 799***********997777777777766666664 PP

>> TPR_6  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0     0.061        92      12      32 ..      50      70 ..      35      71 .. 0.86
   2 ?    3.9   0.1     0.066        99      13      30 ..     147     170 ..     129     174 .. 0.66
   3 ?   -2.9   0.0       9.5   1.4e+04       1       9 [.     300     308 ..     300     314 .. 0.82
   4 ?   -2.0   0.0       4.9   7.3e+03      17      31 ..     338     352 ..     337     352 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.061
                HHHHHHHHHHHHHHHHHH-TT CS
       TPR_6 12 klgdtdkAlealerlikeYPd 32
                ++gd+ kA++ + r i+ Y +
  EEA21393.1 50 RAGDPVKAMRFFMRAIEIYDN 70
                458**************9965 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.066
                 H......HHHHHHHHHHHHHHHH- CS
       TPR_6  13 l......gdtdkAlealerlikeY 30 
                        g+ ++A+++l++ ++ +
  EEA21393.1 147 EskraneGRIQEAMKYLNEALELF 170
                 045555589999999999888755 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 9.5
                 HHHHHHHHH CS
       TPR_6   1 dAlyklals 9  
                 ++ly+ +++
  EEA21393.1 300 EVLYRSGRA 308
                 689999987 PP

  == domain 4  score: -2.0 bits;  conditional E-value: 4.9
                 HHHHHHHHHHHHH-T CS
       TPR_6  17 dkAlealerlikeYP 31 
                 ++Al+ +++ i + P
  EEA21393.1 338 AEALTSFNSAIADNP 352
                 79******9999877 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.0     0.021        31      12      42 ..      49      86 ..      45      88 .. 0.55
   2 ?    8.8   0.2    0.0022       3.4      12      37 ..     151     176 ..     134     183 .. 0.75
   3 ?   -2.2   0.0       7.7   1.1e+04       5      18 ..     296     309 ..     287     310 .. 0.79
   4 ?   -0.7   0.0       2.5   3.7e+03      18      32 ..     338     352 ..     337     363 .. 0.87
   5 ?   -1.9   0.3       6.1   9.1e+03       9      18 ..     437     446 ..     428     465 .. 0.46

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.021
      TPR_14 12 lalGdpde.......AiallrralalaPddaeawllla 42
                +++Gdp +       Ai++++  la++P++ ++ +  a
  EEA21393.1 49 WRAGDPVKamrffmrAIEIYDNGLAKFPTSFDLAYNKA 86
                66666666111111155555555557777766665555 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0022
      TPR_14  12 lalGdpdeAiallrralalaPddaea 37 
                 ++ G+ +eA+++l++al+l+   +++
  EEA21393.1 151 ANEGRIQEAMKYLNEALELFQRCLVV 176
                 35699*************98665555 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 7.7
      TPR_14   5 lalaeallalGdpd 18 
                 +al e+l+++G+ d
  EEA21393.1 296 AALTEVLYRSGRAD 309
                 57778899999876 PP

  == domain 4  score: -0.7 bits;  conditional E-value: 2.5
      TPR_14  18 deAiallrralalaP 32 
                 +eA++ ++ a+a++P
  EEA21393.1 338 AEALTSFNSAIADNP 352
                 589*********998 PP

  == domain 5  score: -1.9 bits;  conditional E-value: 6.1
      TPR_14   9 eallalGdpd 18 
                 ++ ++ Gd +
  EEA21393.1 437 ALARRDGDSE 446
                 2233344443 PP

>> DALR_2  DALR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.1       1.3     2e+03      22      37 ..       7      22 ..       6      38 .. 0.57
   2 ?    6.1   0.2      0.01        15      10      55 ..     132     170 ..     130     180 .. 0.64
   3 ?    2.6   0.0      0.13   1.9e+02      39      62 ..     465     490 ..     438     491 .. 0.70

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 1.3
                HHHHHHHHHHTT-HHH CS
      DALR_2 22 lakeiNralkeedkaa 37
                l ke+N a+++++k+ 
  EEA21393.1  7 LLKELNNAKNKSKKKG 22
                6789998333333332 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.01
                 --HHHHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHGGGT-S CS
      DALR_2  10 FNTaeAiavlFelakeiNralkeedkaaasalkallrelaevLGll 55 
                 FNTa+ ++ l e   e  ra++++ ++a + l+++l+       l+
  EEA21393.1 132 FNTAQVLTSLAEALTESKRANEGRIQEAMKYLNEALE-------LF 170
                 9999999999999888777333333333333333333.......33 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.13
                 HHHHHHHHHH..HGGGT-S-S-HHHH CS
      DALR_2  39 salkallrel..aevLGllqeepeaf 62 
                 +++ ++lr++  ++v+G+ qe +e+ 
  EEA21393.1 465 KTKLDQLRSVdsEKVMGIAQEMIEDG 490
                 3333666666889*******988875 PP

>> FlgN  FlgN protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   1.7   0.00012      0.18      92     132 ..     134     174 ..     114     187 .. 0.82
   2 ?    1.0   1.2      0.38   5.7e+02      46     103 ..     183     248 ..     180     252 .. 0.75
   3 ?   -0.3   0.1      0.94   1.4e+03      84     104 ..     359     379 ..     337     384 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00012
                 HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHXX CS
        FlgN  92 lwqelkelleelkelnelNgrlieqslefnqrllnllqgaa 132
                   q l++l+e+l e  ++N+  i+ ++++++++l+l+q+  
  EEA21393.1 134 TAQVLTSLAEALTESKRANEGRIQEAMKYLNEALELFQRCL 174
                 55779********************************9855 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.38
                 HHHHHHHHHHHHHHHHHHHHHHTT--.......SCHHHHHHHHCT....TCCHHHHHHHHHHHHHHHHH CS
        FlgN  46 ekqellekleqleqkrakllaelgls.......aeeatlsellak....eedeelkelwqelkelleel 103
                 e qe+++ le++e     + + ++++       + ++++ +        ++d+ + +++++l++l+  +
  EEA21393.1 183 ESQEQIKMLEANETPQTSAEEPAAEEmdteseaPPQEEWAA---VvepvTKDTLVDTAVAQLETLATLC 248
                 56888888888888888888888888888855544444444...4445999999999999999998766 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.94
                 TCCHHHHHHHHHHHHHHHHHH CS
        FlgN  84 eedeelkelwqelkelleelk 104
                 e +++l + wq+l+++le+l 
  EEA21393.1 359 EVQKSLVSRWQALTAALEALT 379
                 468889999999999998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (502 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1014  (0.0565564); expected 358.6 (0.02)
Passed bias filter:                      614  (0.0342462); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.47
# Mc/sec: 3205.81
//
Query:       EEA21394.1  [L=225]
Description: MIND kinetochore complex component Nnf1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.3e-33  112.9   3.4    9.3e-33  112.9   3.4    2.2  3  Nnf1      Nnf1
  ------ inclusion threshold ------
      0.083   12.2   2.0       0.39   10.0   0.9    2.0  2  WD-3      WD-repeat region
       0.86    9.7   4.7        5.5    7.1   3.3    2.1  2  COG2      COG (conserved oligomeric Golgi) complex component,


Domain annotation for each model (and alignments):
>> Nnf1  Nnf1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.1      0.86   5.1e+03      51      68 ..      10      23 ..       2      52 .. 0.51
   2 !  112.9   3.4   1.6e-36   9.3e-33       2     110 .]      71     176 ..      70     176 .. 0.96
   3 ?    0.2   0.1      0.16   9.5e+02      30      56 ..     177     203 ..     175     222 .. 0.62

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.86
                -T..........TTSSTT CS
        Nnf1 51 egeeeasrpevpphtLpP 68
                ++++e++     p  LpP
  EEA21394.1 10 SQQREGDS----PSPLPP 23
                22333332....222333 PP

  == domain 2  score: 112.9 bits;  conditional E-value: 1.6e-36
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHCCHH-T..........TTSSTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        Nnf1   2 aLesvhkqmvefleesiraefeeIleerdvvekLneLDdlieeAkerreegeeeasrpevpphtLpPeeliaahlapakkeeqeeLearlqeleaenae 100
                 +Lesvh+q++++lee + aef+eI++er+v + LneLD+l+ eA++r+++ge+e   ++vpph L+++ l++ahl+p+++e+q +L++++++ +++na+
  EEA21394.1  71 SLESVHRQLNAKLEEGATAEFNEIIKEREVIKGLNELDRLVGEARRRKSQGESE---SDVPPHMLDADGLYRAHLTPYLQEAQVALNTKIETAQSQNAA 166
                 79***********************************************98776...447*************************************** PP

                 HHHHHHHHHH CS
        Nnf1 101 laeeveeqre 110
                 lae+v +qr+
  EEA21394.1 167 LAEKVLAQRK 176
                 ********96 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.16
                 THHHHHHHHHHHHHHHHCCHH-T.... CS
        Nnf1  30 dvvekLneLDdlieeAkerreegeeea 56 
                 ++++ L+ L++++++ +  +++++e +
  EEA21394.1 177 EIESLLSGLEAVMADLEGSAKTSTEYS 203
                 788889999988776665555443333 PP

>> WD-3  WD-repeat region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0     0.039   2.3e+02      44      96 ..      74     127 ..      61     135 .. 0.81
   2 ?   10.0   0.9   6.5e-05      0.39      35     102 ..     143     209 ..     135     223 .. 0.78

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.039
                 EEEETTCEEETTTS--.....-TT--HHHHHHHHHHHS-----------.-G.. CS
        WD-3  44 evswkLktkleknekilkqrlqqskdledFlqelkellesekalkskkeses.l 96 
                 +v+++L++kle+  +   +++ +  ++ + l+el  l+ + ++ ks+ eses +
  EEA21394.1  74 SVHRQLNAKLEEGATAEFNEIIKEREVIKGLNELDRLVGEARRRKSQGESESdV 127
                 5899999999888888888999999999999*******9888888887777643 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 6.5e-05
                 TTC-TT-EEEEEETTCEEETTTS--.....-TT--HHHHHHHHHHHS-----------.-G.GG--HH CS
        WD-3  35 dpelkkarlevswkLktkleknekilkqrlqqskdledFlqelkellesekalkskkeseslpsakyy 102
                 +p l++a++  + k++t  ++n +++++ l+q k++e++l+ l+ ++++ + + +++++ s + +++ 
  EEA21394.1 143 TPYLQEAQVALNTKIETAQSQNAALAEKVLAQRKEIESLLSGLEAVMADLEGSAKTSTEYS-KTHNLR 209
                 467999*****************************************96665555554444.444444 PP

>> COG2  COG (conserved oligomeric Golgi) complex component, COG2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.0      0.04   2.4e+02      81     127 ..      68     112 ..      52     117 .. 0.58
   2 ?    7.1   3.3   0.00091       5.5      58     124 ..     151     217 ..     146     222 .. 0.88

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.04
        COG2  81 arkkvesvreklsereeeveskleeakeleekrellklllkldevve 127
                 +   +esv+++l+++ ee  +  +e +e+ ++re++k l +ld++v 
  EEA21394.1  68 VPASLESVHRQLNAKLEE--GATAEFNEIIKEREVIKGLNELDRLVG 112
                 444444555555444442..344444555556677777777777765 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.00091
        COG2  58 vslSghLvglqeeleevesplaaarkkvesvreklsereeeveskleeakeleekrellklllklde 124
                 v l ++    q++   +  +++a rk++es+ + l++ ++++e+  +  +e  ++ +l +  l++de
  EEA21394.1 151 VALNTKIETAQSQNAALAEKVLAQRKEIESLLSGLEAVMADLEGSAKTSTEYSKTHNLRQESLQIDE 217
                 667777888899999999**********************************999998888877776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (225 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1050  (0.0585643); expected 358.6 (0.02)
Passed bias filter:                      470  (0.0262145); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.23s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 1562.36
//
Query:       EEA21395.1  [L=450]
Description: cAMP receptor-like protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.1e-13   48.6   6.2    6.1e-13   48.6   6.2    2.1  2  Dicty_CAR      Slime mold cyclic AMP receptor
    5.7e-07   29.1   6.8    7.7e-07   28.7   6.8    1.2  1  7tm_1          7 transmembrane receptor (rhodopsin family)
    6.6e-06   26.0  10.6    1.3e-05   25.1  10.6    1.4  1  Git3           G protein-coupled glucose receptor regulating 
    0.00043   19.7   2.3    0.00077   18.9   2.3    1.4  1  7TM_GPCR_Srsx  Serpentine type 7TM GPCR chemoreceptor Srsx
  ------ inclusion threshold ------
      0.047   13.9   0.8      0.093   13.0   0.8    1.5  1  Lir1           Light regulated protein Lir1
        5.5    7.1   6.9        1.9    8.6   3.1    2.2  2  GPR_Gpa2_C     G protein-coupled glucose receptor regulating 


Domain annotation for each model (and alignments):
>> Dicty_CAR  Slime mold cyclic AMP receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.6   6.2     2e-16   6.1e-13      18     175 ..      19     186 ..       5     221 .. 0.79
   2 !    5.2   1.9    0.0034        10     202     255 ..     322     377 ..     307     386 .. 0.73

  Alignments for each domain:
  == domain 1  score: 48.6 bits;  conditional E-value: 2e-16
   Dicty_CAR  18 dfssilgcllvligfwrlkllrnhitkvialfcatsllkdlisti.ltlleeaqesgfqcylyaivitygslacwlwtlclalsiynlivkrepep..e 113
                  + s++g+++v+ +f   + +r+ i +v+ +   + +l ++ + i  t + +++++   c +   +i +   a  lwt+ +a+ +y+   +++      
  EEA21395.1  19 SILSVIGTTIVIGTFLSSHSFRKPINRVVFYAAWANILTNVGTLIsRTAIVQKEKGEALCRFQGFIIQWFMPADALWTFAMAFNVYLTFFHKYDATilR 117
                 5779*************************999999999998766524666788888999****************************999988764336 PP

   Dicty_CAR 114 kfekyyfvlcwglplistivml.....skk.vievvgnwcwigekyvgyrfglfygpfli.iwaisavl 175
                 ++e  y vlc+glp+i +   +     sk  v      wcw++ +++  r+++fygp ++ i+ + a+ 
  EEA21395.1 118 HLEWKYLVLCYGLPFIPSFAYFfigssSKGpVYGSATLWCWVSVEWDILRIAVFYGPVWFvILLTFAIY 186
                 89999***********8865432222244423345667*******************755155555654 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0034
   Dicty_CAR 202 qfklinyiivflvcwvfavvnrilnglnlfpal..vnilhtylsvshgfyasvtfi 255
                     + y i +lv wv + vnr+   +    a+  ++ + +++   +gf+ s+ +i
  EEA21395.1 322 FKYAVLYFIALLVTWVPSTVNRVYSLFYPNDAIfgLEFVSAFVLPLQGFWNSIIYI 377
                 3345789***************9876533333311345566666678999999887 PP

>> 7tm_1  7 transmembrane receptor (rhodopsin family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.7   6.8   2.6e-10   7.7e-07       3     256 ..      27     373 ..      25     376 .. 0.68

  Alignments for each domain:
  == domain 1  score: 28.7 bits;  conditional E-value: 2.6e-10
                 HHHHHHHHHSTTTCSHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCHSSCHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTTHHHHCHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       7tm_1   3 llvllviltkkslrtstnyfilsLaiaDlllgllvlpfaivyelttgewlfgevlCklwlsldvflstasilnllaisiDRYlaivkplkykrkrtkrr 101
                 ++v+ ++l ++s+r++ n+ ++  a a++l+ + +l     + +   +   ge+lC+++ ++   ++ a  l   a++++ Yl+ ++++ +     ++ 
  EEA21395.1  27 TIVIGTFLSSHSFRKPINRVVFYAAWANILTNVGTLI--SRTAI--VQKEKGEALCRFQGFIIQWFMPADALWTFAMAFNVYLTFFHKYDATIL--RHL 119
                 579999************************8653332..22223..456679***********************************7666666..569 PP

                 HHHHHHHHHHHHHHHHHHHHHHCEECC..CTTTTCCEEECSSSTHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHCHHHHSHCCH.......... CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......... RF
       7tm_1 102 avllillvWvlslllsvpllvletvet..naedttkdCqittleesvyiifsavlsfilPllvivilyarifrtvlktsrtktskskng.......... 188
                  + +++l++ l ++ s+ +++++++++  +  + t  C ++ +   ++ i ++     + +l+++ +yar+ + + ++++t +s +k+           
  EEA21395.1 120 EWKYLVLCYGLPFIPSFAYFFIGSSSKgpVYGSATLWCWVSVEW-DILRIAVFYGPVWFVILLTFAIYARVGIDIAQKRSTLRSFNKEAnmmtddrlnk 217
                 99**********************987654455599****9999.555555555555555788888999999999998888888555556666666666 PP

                 ...............HHHHHC.......................................................................TTCHH.. CS
                 ...............xxxxxx.......................................................................xxxxx.. RF
       7tm_1 189 ...............gsstpp.......................................................................lkavr.. 199
                                     +                                                                       +   r  
  EEA21395.1 218 lfeihaskvvhvtseA----VndatangqrqgsnisnsssnvnvnssnnndnsnttafpaysvtvaggeafplppsttstvgsasvkvspttS---Rrv 309
                 6666555555555550....0444444444555555555555566566666666666666666666666666666666666665555554441...134 PP

                 .....H...HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTSCCHHHHHHHHHHHHHHHHHHHH CS
                 .....x...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       7tm_1 200 .....e...kkaartlgivvavfivcwlPftiiyllqalsvqceasellptalkliavwlgysns 256
                      +      ++  ++  ++ +v+w+P t+  +++ + ++    +l   + +++  + g++ns
  EEA21395.1 310 prmdiSsaaFAYFKYAVLYFIALLVTWVPSTVNRVYSLFYPNDAIFGLEFVSAFVLP-LQGFWNS 373
                 4333312346677788888888999*******9999999444433333333333333.4444444 PP

>> Git3  G protein-coupled glucose receptor regulating Gpa2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1  10.6   4.3e-09   1.3e-05      11     198 ..      18     196 ..       6     200 .. 0.73

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 4.3e-09
        Git3  11 assvsilaglvalylllaidkrrrvfRhe...LillLilvdllkalvlliypvkvlvenkvyassafcqvvGfflavaiegsdlailllavhtallvfk 106
                 +s++s++ +++ + ++l+     ++fR+    ++++   +++l  +  li + +++v  + ++ +a+c+ +Gf+++  +++  l+ +++a  ++l+ f+
  EEA21395.1  18 TSILSVIGTTIVIGTFLSS----HSFRKPinrVVFYAAWANILTNVGTLI-SRTAIV--QKEKGEALCRFQGFIIQWFMPADALWTFAMAFNVYLTFFH 109
                 5777888777777777775....566665222455555666666677777.555555..4567899******************************999 PP

        Git3 107 pnlrnkksknvegGLykyrkyvyvisv.lvplllasLa..fin..akregYkplsawcylpeepvwyrlvlswiprYiivvaivaiyisiyiyvrre 198
                           + + + +  ++ y + +  +p +  s a  fi+   k  +Y +++ wc+++ e    r+++ ++p +++++ ++aiy+ + i + ++
  EEA21395.1 110 K---------YDATILRHLEWKYLVLCyGLPFI-PSFAyfFIGssSKGPVYGSATLWCWVSVEWDILRIAVFYGPVWFVILLTFAIYARVGIDIAQK 196
                 7.........44444444444444444244443.3333116666678889**************************************998888766 PP

>> 7TM_GPCR_Srsx  Serpentine type 7TM GPCR chemoreceptor Srsx
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   2.3   2.6e-07   0.00077       2     177 ..      20     199 ..      19     227 .. 0.84

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 2.6e-07
  7TM_GPCR_Srsx   2 viGliGNvllilltlkkkkLrskssiLicvlciadllclvgelvfvvlllrktqlkreeCFlliivyvfallaqsvllLvigiDlli..avkfPir 95 
                    ++++iG  ++i  +l ++++r +++  ++  + a++l +vg+l+++   + +++   + C +  ++   ++ a ++   ++++ + +  + k+ ++
     EEA21395.1  20 ILSVIGTTIVIGTFLSSHSFRKPINRVVFYAAWANILTNVGTLISRTAIV-QKEKGEALCRFQGFIIQWFMPADALWTFAMAFNVYLtfFHKYDAT 114
                    899***********************************************.78888999*999999999999999999999987654114455555 PP

  7TM_GPCR_Srsx  96 YrllskekYllillifpvlysvfilvigflqidde...tvlvCapplalagkaseiftlssliinvlvllvylvliiilkkkkek 177
                      +  ++kYl+++  +p++ s + ++ig            l C +++  +     +f   + ++ +l++ +y+ + i + +k+++
     EEA21395.1 115 ILRHLEWKYLVLCYGLPFIPSFAYFFIGSSSKGPVygsATLWCWVSVEWDILRIAVFYGPVWFVILLTFAIYARVGIDIAQKRST 199
                    55666788********************998776544588999999999999999999999999999999999888877766664 PP

>> Lir1  Light regulated protein Lir1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.8   3.1e-05     0.093      21      78 ..     227     283 ..     213     321 .. 0.74

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 3.1e-05
        Lir1  21 lkklailspakvaasslsslrsrvraaaa.vavdastvDysssisvfPaeaCdligGea 78 
                 ++  ++++ +  +a + + + s+++ +++ v+v++s+ + +s++  fPa +  + gGea
  EEA21395.1 227 VHV-TSEAVNDATA-NGQRQGSNISNSSSnVNVNSSNNNDNSNTTAFPAYSVTVAGGEA 283
                 332.3333333323.3334456777777779***************************9 PP

>> GPR_Gpa2_C  G protein-coupled glucose receptor regulating Gpa2 C-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.1       1.7     5e+03      15      32 ..     171     188 ..     164     202 .. 0.75
   2 ?    8.6   3.1   0.00064       1.9      15      68 ..     322     377 ..     310     380 .. 0.71

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 1.7
  GPR_Gpa2_C  15 fiYPlaYiilwlfPfvah 32 
                 f  P+ ++il +f + a 
  EEA21395.1 171 FYGPVWFVILLTFAIYAR 188
                 555888888888887665 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.00064
  GPR_Gpa2_C  15 fiYPlaYiilwlfPfvahvlqydye..lkekpviwllvvaavvqplnglVDtlvfl 68 
                 f Y + Y i  l + v ++++  y+   +++ ++ l +v+a+v+pl+g+ ++++++
  EEA21395.1 322 FKYAVLYFIALLVTWVPSTVNRVYSlfYPNDAIFGLEFVSAFVLPLQGFWNSIIYI 377
                 44555555555555555555555552259***********************9997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (450 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       793  (0.04423); expected 358.6 (0.02)
Passed bias filter:                      405  (0.0225891); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.41
# Mc/sec: 3329.32
//
Query:       EEA21396.1  [L=409]
Description: cyclin-dependent protein kinase PhoA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.5e-75  252.8   0.0    4.3e-75  252.5   0.0    1.1  1  Pkinase        Protein kinase domain
    3.6e-37  128.1   0.0      5e-37  127.6   0.0    1.1  1  Pkinase_Tyr    Protein tyrosine kinase
    3.2e-05   23.1   0.1     0.0003   19.8   0.1    2.1  1  Haspin_kinase  Haspin like kinase domain
     0.0016   17.9   0.5      0.016   14.5   0.1    2.5  3  Kinase-like    Kinase-like
  ------ inclusion threshold ------
      0.016   14.6   0.4      0.016   14.6   0.4    1.9  2  Kdo            Lipopolysaccharide kinase (Kdo/WaaP) family
      0.055   13.4   2.7      0.062   13.2   0.0    2.2  2  APH            Phosphotransferase enzyme family
      0.085   11.9   0.0       0.14   11.1   0.0    1.3  1  Seadorna_VP7   Seadornavirus VP7


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  252.5   0.0   1.7e-78   4.3e-75       1     264 []      89     371 ..      89     371 .. 0.95

  Alignments for each domain:
  == domain 1  score: 252.5 bits;  conditional E-value: 1.7e-78
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHSCTTB--EEEEEEESSEEEEEEE--TTEBHHHHHH...HHSS-- CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklkhpnivrlyevfeekdelylvleyveggeladlle...rkgsls 96 
                 +++leklGeG++++V+k+++++tg++vA+K+i  ++++ +  ++++rEi+++k+lkh+ iv ly+v++++++l+lv+ey++ + l++++    ++gsl+
  EEA21396.1  89 FQQLEKLGEGTYATVFKGRNRQTGEMVALKEIHLDSEEGTP-STAIREISLMKELKHESIVSLYDVIHTENKLMLVFEYMDRD-LKRYMDtkgDHGSLD 185
                 6789*******************************998755.7**************************************66.9999887888999** PP

                 HHHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCS.BCTTTSCGGGS-HHHH.TTSCBSHHHHHHHHHHHHHHHHHS CS
     Pkinase  97 eeeakkiakqilegleylHskgiiHrDlKpeNiLidekgelKitDFGlakelesssk.ltsfvgtseYlAPEvl.keneyskkvDvWslGvilyelltg 193
                   ++k++++q+++g++++H+++++HrDlKp+N+Li++kg+lK++DFGla+ +    + ++++v+t +Y+AP vl +++ y +++D+Ws+G+i++e++tg
  EEA21396.1 186 YVTIKSFMHQLMRGIAFCHENRVLHRDLKPQNLLINKKGQLKLADFGLARAFGIPVNtFSNEVVTLWYRAPDVLlGSRTYNTSIDIWSAGCIMAEMYTG 284
                 ****************************************************9998889***************999********************** PP

                 S-STTTSSHHHHHHHHHHTHHHHHHHCT.SHH...HHHTTS......................-HHHHHHHHHHT-SSGCCSTTHHHHHTSGGG CS
     Pkinase 194 kppfsgekgkekvekeldqlekilkilg.etkeklpeasei......................seeakdllkkllkkdpkkRltaeellqhpyl 264
                 +p+f+   g++    + dql+ki++++g +++ ++p  s++                      ++  +dll+++l+  p+ R++a+++l+hp++
  EEA21396.1 285 RPLFP---GTT----NEDQLQKIFRLMGtPSERSWPGISQFpeykpnfhvyatqdlrlilpqiDQLGLDLLTRMLQLRPEMRISAADALRHPWF 371
                 *****...444....56788889999998889999999999****************************************************8 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.6   0.0     2e-40     5e-37       3     219 ..      91     301 ..      89     313 .. 0.91

  Alignments for each domain:
  == domain 1  score: 127.6 bits;  conditional E-value: 2e-40
                  EEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHT.CTTT CS
  Pkinase_Tyr   3 lgkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkklkhpnivkllgvctkeepllivteyvkgGdLlkfLrkk.ekek 99 
                    +klGeG++++V++g+ +    ++ + Va+K ++ +++e + +  ++e+++mk+lkh+ iv+l+ v+  e++l++v+ey++  dL+ ++ +k ++ +
   EEA21396.1  91 QLEKLGEGTYATVFKGRNR----QTGEMVALKEIHLDSEEGTPSTAIREISLMKELKHESIVSLYDVIHTENKLMLVFEYMDR-DLKRYMDTKgDHGS 183
                  6799*************99....9999**************9***************************************97.9*****99956789 PP

                  SBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEETTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSE.EEHHHHHHHHHHHHH CS
  Pkinase_Tyr 100 ltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsenkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekk.ftsksDvWsfGvllw 196
                  l++ ++ sf++q+ +G+++ ++++++Hrdl  +N L++++ + k++DfGLar+       ++ +++ + + + ap +l  ++ ++++ D+Ws G ++ 
   EEA21396.1 184 LDYVTIKSFMHQLMRGIAFCHENRVLHRDLKPQNLLINKKGQLKLADFGLARAF--GIPVNTFSNEVVTLWYRAPDVLLGSRtYNTSIDIWSAGCIMA 279
                  99***************************************************9..44445556666777777***987665599999********** PP

                  HHHTTSSGTTTTSHHHHHHHHHH CS
  Pkinase_Tyr 197 Eiftlgespypglkneevleklk 219
                  E++t g+  +pg +ne+ l+k+ 
   EEA21396.1 280 EMYT-GRPLFPGTTNEDQLQKIF 301
                  ****.**********99998874 PP

>> Haspin_kinase  Haspin like kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.1   1.2e-07    0.0003     109     257 ..      96     237 ..      79     269 .. 0.61

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 1.2e-07
  Haspin_kinase 109 seklssevyqtke..kdkevvlKviplevledvtis..kelsl.kelkslklvkgtypglllllqdkvlkekpdfyseqqlflvlllkdkGtdLee 199
                    +e+ +  v++ ++  + + v+lK i l+  e    +  +e+sl kelk   +v            d +         ++++ l+l+++++  dL++
     EEA21396.1  96 GEGTYATVFKGRNrqTGEMVALKEIHLDSEEGTPSTaiREISLmKELKHESIVSLY---------DVI---------HTENKLMLVFEYMDRDLKR 173
                    66666666666664444556666666644333222211222222333333333222.........222.........2334566667777777766 PP

  Haspin_kinase 200 v.......klkswkqalsifwqivkiLyvaEtkfeFEHRdLhldniLvdknlnvtlidlklsRle 257
                               ++ +++s ++q +  ++   ++ +  HRdL+ +n L++k+++  l d+ l+R+ 
     EEA21396.1 174 YmdtkgdhGSLDYVTIKSFMHQLMRGIAFCHEN-RVLHRDLKPQNLLINKKGQLKLADFGLARAF 237
                    554433323457899999*****9998877655.456**************************96 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0      0.38   9.7e+02      16      50 ..      91     125 ..      80     146 .. 0.80
   2 !   14.5   0.1   6.2e-06     0.016     137     190 ..     177     233 ..     137     277 .. 0.80
   3 ?    0.0   0.0      0.16   4.2e+02      97     163 ..     317     384 ..     289     401 .. 0.79

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.38
  Kinase-like  16 rgellkkgdrsvvfevkdqetgeplavkvfllpse 50 
                  + e l++g    vf+ ++ +tge +a+k   l se
   EEA21396.1  91 QLEKLGEGTYATVFKGRNRQTGEMVALKEIHLDSE 125
                  556788899999*************9998887774 PP

  == domain 2  score: 14.5 bits;  conditional E-value: 6.2e-06
  Kinase-like 137 t...hkkletiarlllTlqlirlaanLqakglvhgkftvdnllldekgglmlggfta 190
                  t   h +l ++  +    ql+r +a  +++ ++h +++++nll ++kg+l+l +f+ 
   EEA21396.1 177 TkgdHGSLDYVTIKSFMHQLMRGIAFCHENRVLHRDLKPQNLLINKKGQLKLADFGL 233
                  234588899998888889*************************************75 PP

  == domain 3  score: 0.0 bits;  conditional E-value: 0.16
  Kinase-like  97 pfiqlkskesiywvvnallllpaa.svdleilnkvlqkrsethkkletiarlllTlqlirlaanLqak 163
                  +f + k++ ++y+  ++ l+lp++ ++ l++l  +lq r+e + + +++ r+    +l +l a+Lq++
   EEA21396.1 317 QFPEYKPNFHVYATQDLRLILPQIdQLGLDLLTRMLQLRPEMRISAADALRHPWFNDLPQLQAQLQQH 384
                  56677888888888888888887746899999999999999999999998888888888888888753 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.4   6.1e-06     0.016      56     166 ..     130     231 ..     109     236 .. 0.86
   2 ?   -2.1   0.1       0.8     2e+03     104     127 ..     376     399 ..     371     404 .. 0.71

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 6.1e-06
         Kdo  56 travrEfrllkrLeeagvavpkpvaagavkvgleyrAlllterlegaqdLedllakwae...laeelkrallkavgrliaklhragvnHadlyaknill 151
                  +a rE++l+k+L+++ +  ++ v   ++k       +l+ e ++  +dL+ ++ +  +   l+    +  ++++ r ia  h+  v H+dl ++n+l+
  EEA21396.1 130 STAIREISLMKELKHESIVSLYDVIHTENKL------MLVFEYMD--RDLKRYMDTKGDhgsLDYVTIKSFMHQLMRGIAFCHENRVLHRDLKPQNLLI 220
                 58999*********99999999998877765......79999999..699999988666687888888999**************************** PP

         Kdo 152 qqeeeeeaeiwliDl 166
                 ++++    ++ l D+
  EEA21396.1 221 NKKG----QLKLADF 231
                 *999....6666666 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.8
         Kdo 104 dLedllakwaelaeelkrallkav 127
                  L++ l+++++ +++ ++a+l   
  EEA21396.1 376 QLQAQLQQHHQQQHHQQQAQLPGY 399
                 577788888888888888877655 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   2.4e-05     0.062     165     197 ..     205     235 ..     159     237 .. 0.87
   2 ?   -1.0   0.9      0.54   1.4e+03     115     143 ..     363     391 ..     315     397 .. 0.59

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 2.4e-05
                 -EEEE-SS-SGGGEEEC..TTEEEEE---TT-E CS
         APH 165 ptvllHgDlhpgNllvdpddgrvtGviDfedag 197
                 + ++lH+Dl+p+Nll++  +g++  + Df++a+
  EEA21396.1 205 ENRVLHRDLKPQNLLIN-KKGQL-KLADFGLAR 235
                 5689*************.77777.578888775 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.54
                 B-SHHCHTCCHHHHHHCHHHCCCGCCTCC CS
         APH 115 ladflaqdlellrqlesatarllaselld 143
                  +  ++++ ++l+ql ++ +++++ + ++
  EEA21396.1 363 ADALRHPWFNDLPQLQAQLQQHHQQQHHQ 391
                 23333444555555555554444444443 PP

>> Seadorna_VP7  Seadornavirus VP7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   5.6e-05      0.14     158     186 ..     204     230 ..     187     247 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 5.6e-05
  Seadorna_VP7 158 hsestnllhGDcnpenlmcDknGylklvD 186
                   h  ++ +lh D +p+nl+ +k G+lkl D
    EEA21396.1 204 H--ENRVLHRDLKPQNLLINKKGQLKLAD 230
                   4..7789********************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (409 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       869  (0.048469); expected 358.6 (0.02)
Passed bias filter:                      557  (0.031067); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.61u 0.27s 00:00:00.88 Elapsed: 00:00:00.45
# Mc/sec: 2739.40
//
Query:       EEA21397.1  [L=382]
Description: SIR2 family histone deacetylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.7e-30  105.2   0.0    5.9e-30  104.5   0.0    1.3  1  SIR2      Sir2 family
  ------ inclusion threshold ------
       0.12   12.8   0.0       0.24   11.8   0.0    1.5  1  Rimk_N    RimK PreATP-grasp domain


Domain annotation for each model (and alignments):
>> SIR2  Sir2 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.5   0.0   6.5e-34   5.9e-30       1     176 [.      60     315 ..      60     316 .. 0.93

  Alignments for each domain:
  == domain 1  score: 104.5 bits;  conditional E-value: 6.5e-34
                 -GGGGGGGT---SSSTTSHHHHSCHHH.HSSHHHHHHHHHHHHHHHHHHHHHHHCC.TSS--HHHHHHHHHHHTTCEEEEEES-SSSHHHHTT-S.SEE CS
        SIR2   1 GAGiStesGipdfRskeGlyaklakee.laspealfskkllveevfyniarellae.eaepnaaHkalkklekkgkllrliTQNiDgLekkaGsk.kvv 96 
                 GAGiS++sG+ d+R+++G y + ++++  +  e +++++ ++++ + +++  ++   +a+pn++Hka++ l kkg ++++iTQN+D  +  a      +
  EEA21397.1  60 GAGISVASGLSDYRGENGTYVRNKSYRpTYYHEFITRHEARKRY-WARSYVGWPGLlKAKPNTTHKAVTDLGKKGYVSNVITQNVDSFHMVAHPDlSTI 157
                 9**********************999846666666677777777.********9999***********************************99999** PP

                 ETTEEEEEEEETTTSBEEECCGGHCHHHCCTT.................................................B-TTTCC........... CS
        SIR2  97 elHGslakakcvkcekkldkeelqeeieaekvp................................................ecekcgk........... 136
                 elHG l  + c++c++ + ++e q+++++ +++                                                 c++c +           
  EEA21397.1 158 ELHGFLRGVICINCHNLVPRDEFQQSLTQLNPAwaeflhemlesgaldtnnpeeqrkrglkinpdgdvdlphapysnfrypACPHCLEkppsvqdgqpe 256
                 *****************************999999*************999999999999999999999999999999999888888899999999999 PP

                 ..................BEEEEE--CTSB-SHHHHHHHH.HHHH-SEEEEES--STST CS
        SIR2 137 ..................llkpdvvfFGealpdklkklie.kveeadlllviGtSlkVa 176
                                   +lkp v++FGe+   ++++++e ++++a  ll++G+Sl+ +
  EEA21397.1 257 avvetepdgawspsstagILKPAVIMFGESTSPSVRSAAEeAIDDAGRLLIMGSSLATY 315
                 9999999999******99**************9999998889*************9865 PP

>> Rimk_N  RimK PreATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   2.7e-05      0.24       2      34 ..     304     336 ..     304     342 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 2.7e-05
      Rimk_N   2 kiaiLsrnpelystrrLveaaekrghevevldp 34 
                 +++i+ ++   ys  rLve a+krg+ + ++++
  EEA21397.1 304 RLLIMGSSLATYSAYRLVERAHKRGMAIGIINV 336
                 5789999999********************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (382 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       521  (0.0290591); expected 358.6 (0.02)
Passed bias filter:                      506  (0.0282224); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.35s 00:00:01.00 Elapsed: 00:00:00.56
# Mc/sec: 2057.24
//
Query:       EEA21398.1  [L=474]
Description: cation efflux family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.4e-57  193.9   5.2    3.3e-57  193.5   5.2    1.2  1  Cation_efflux  Cation efflux family
    3.8e-05   23.7   0.1    7.7e-05   22.7   0.1    1.6  1  ZT_dimer       Dimerisation domain of Zinc Transporter
  ------ inclusion threshold ------
        6.8    7.3  24.7         12    6.5   3.8    3.7  3  UreE_C         UreE urease accessory protein, C-terminal doma


Domain annotation for each model (and alignments):
>> Cation_efflux  Cation efflux family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  193.5   5.2   5.5e-61   3.3e-57       2     198 ..     120     340 ..     119     341 .. 0.98

  Alignments for each domain:
  == domain 1  score: 193.5 bits;  conditional E-value: 5.5e-61
  Cation_efflux   2 ilsllanlilalvelivglltnSlalladafhslsdlvsllllllalklsrkppderfpfGygrlevlgalvsgllllglavfllleaiqkli... 94 
                    +++l++nl++a+ ++++g++++S+al+ada+h+l+dlvs++++l ++ +s kpp+erfp+Gyg++e+lgal +++lll++++f+ l+a q l+   
     EEA21398.1 120 RIGLFVNLAMAIGKFVGGYIFHSQALIADAYHALTDLVSDFMTLGTVSWSLKPPSERFPNGYGKVESLGALGVSSLLLCGGFFMGLDATQALLsqf 215
                    689********************************************************************************************* PP

  Cation_efflux  95 .......................kegereihaglalvvalvslvvnlalllilrragrklrsaalkaaalhvlgDaltslgvlvsalvillfnlks 167
                                           ++ e + +++ a+++a++s+v + +l++++++ +++++s++l+++a+h+++D+ltsl++l ++ ++++f+++ 
     EEA21398.1 216 apeafealehagllfhghshshdHGAEVLGPNINAIWLAAGSIVAKEWLYRATMKIAQERKSSVLASNAVHHRIDSLTSLVALATIGGAHIFTNAA 311
                    *********************99999999***************************************************************8887 PP

  Cation_efflux 168 gplaDpvaslligliilysalkllkeslseL 198
                      ++Dpv++l+i+l+++ +++ ++k++l+eL
     EEA21398.1 312 --WLDPVGGLIISLMVINAGWTNTKTALLEL 340
                    ..***************************99 PP

>> ZT_dimer  Dimerisation domain of Zinc Transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   0.1   1.3e-08   7.7e-05       8      78 ..     357     428 ..     345     429 .. 0.81

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 1.3e-08
                 HHHHHHTT.-SS-EEEEEEEEE-S----EEEEEEEE-TTS-HHHHHHHHHHHHHHHHHH-TT--EEEEEEEE CS
    ZT_dimer   8 eireiiks.vpgvkgvhdlrtrksGskifvdlhievdgdlsvkeaHeiadevekrikeefpgvadvliHveP 78 
                 +++ +++s +++ +++ d++  ksG+++++d+++ v ++++v+++ ei + ++  + +++ gv++v +   P
  EEA21398.1 357 ALKTLANStTTQDIQIRDIQGLKSGQNYLMDIEVGVADSMTVQQSREIEEILRTGVGAKVRGVRRVKVRFVP 428
                 33444433566678899*************************************999999999999887666 PP

>> UreE_C  UreE urease accessory protein, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   3.8     0.002        12      72      87 .]      86     101 ..      55     103 .. 0.77
   2 ?    4.5   0.8     0.008        48      57      85 ..     211     239 ..     200     241 .. 0.52
   3 ?    6.1   5.5    0.0025        15      33      87 .]     394     466 ..     386     467 .. 0.48

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.002
      UreE_C  72 kghghhehehghehsH 87 
                 ++ gh++h+h+h+h+H
  EEA21398.1  86 QTRGHAGHGHHHHHHH 101
                 4566666676666666 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.008
      UreE_C  57 vlapfepe.ggAyeaakghgh.....hehehgheh 85 
                  l +f pe  +A e      h     h+h+h+h+h
  EEA21398.1 211 LLSQFAPEaFEALE------HagllfHGHSHSHDH 239
                 55666666323332......222333455555555 PP

  == domain 3  score: 6.1 bits;  conditional E-value: 0.0025
      UreE_C  33 delrieddhvledmlrt..................lgaeveevlapfepeggAyeaakghgh...........hehehghehsH 87 
                 d + +++ + +e++lrt                   g+e  ++ ++f p            +           h+h+h+heh+H
  EEA21398.1 394 DSMTVQQSREIEEILRTgvgakvrgvrrvkvrfvpNGVEGVDFAEEFIPG-----------DvspraspepeeHDHDHDHEHQH 466
                 66677777778888887544444444333333333222222222222222...........03333444443346677777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (474 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       609  (0.0339673); expected 358.6 (0.02)
Passed bias filter:                      452  (0.0252106); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.73u 0.37s 00:00:01.10 Elapsed: 00:00:00.59
# Mc/sec: 2414.32
//
Query:       EEA21399.1  [L=571]
Description: D-xylulose kinase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-31  109.7   0.0    3.3e-31  108.6   0.0    1.6  2  FGGY_C    FGGY family of carbohydrate kinases, C-terminal dom
    3.8e-19   69.2   0.0    7.2e-12   45.4   0.0    2.4  2  FGGY_N    FGGY family of carbohydrate kinases, N-terminal dom


Domain annotation for each model (and alignments):
>> FGGY_C  FGGY family of carbohydrate kinases, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0      0.52   4.7e+03     100     121 ..      97     118 ..      87     121 .. 0.86
   2 !  108.6   0.0   3.7e-35   3.3e-31       1     197 [.     297     512 ..     297     513 .. 0.94

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 0.52
      FGGY_C 100 apywdpdargtitglsssttla 121
                 + yw +da   + gl++++tl+
  EEA21399.1  97 SVYWSADAERLLKGLDKGKTLE 118
                 789************9999976 PP

  == domain 2  score: 108.6 bits;  conditional E-value: 3.7e-35
      FGGY_C   1 akvslGTssflllvgtkpv..isehglltpvagedgkpeyalegsiavagslva.wlldnlglreeirdageveeslaelaaaeavada.......... 86 
                 a+vslGTs+++l++++ ++  +++h++++p++     p  +++++++++g+l   +++d   + +++  a++   ++a++++a ++a+a          
  EEA21399.1 297 AMVSLGTSTTFLMSTPMYKpdPATHFFNHPTT-----PGLHMFMLCYKNGGLAReHVRDA--IDKQVGGAADQ-IPWANFDKALLEAPAmgqkadsdpm 387
                 689**********99999899***********.....9**************99999999..88888888887.8999999999999999999999*** PP

      FGGY_C  87 ......ggvvfvpaf.sglrapywdpdargtitglssstt.lahiarAaleavalqlrailealekd..sgkp..ldrlavdGGgskndllmqllAdil 173
                       +++ +vp++ sg+++++++p+    + +++s+++ + + arA++e+++l+lr + + l+    +g+p  ++r++++GGgs+n+++++++++il
  EEA21399.1 388 kmglffPRPEIVPNLrSGQWRFNYNPQDQS-LEETTSGWDvPLDEARAIVESQFLSLRLRSRGLTTApaEGIPpqPKRVYLVGGGSRNKAIAKIAGEIL 485
                 **************************9776.*********************************888888888899*********************** PP

      FGGY_C 174 g..vpVerpkt.aeatalGaAilAava 197
                 g    V++++  ++a+alGaA++A++ 
  EEA21399.1 486 GgyDGVYKLDVgENACALGAAYKAVWG 512
                 ***9********************985 PP

>> FGGY_N  FGGY family of carbohydrate kinases, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0   1.7e-08   0.00015       1      92 [.       5     107 ..       5     111 .. 0.72
   2 !   45.4   0.0     8e-16   7.2e-12      98     244 ..     133     288 ..     130     289 .. 0.88

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 1.7e-08
                 EEEEEEEESSEEEEEEEETTS-EEEEEEEE--EB-SST........T--EE-....HHHHHHHHHHHHHHHHHHCT.-GCCEEEEEEEE-SS-EEEEET CS
      FGGY_N   1 lilglDcGttstkaivldekgkvvasaqaelelsspke........gwaeqd....peeiwqalaeairkvleqagisekqikaIgisgqreglvllDk 87 
                 l++g+D++t+++k +v++ + kv   a+  + ++s           + ae++    ++ ++qal ++++ + eq +++   +++I+i+gq++g v +  
  EEA21399.1   5 LYIGFDLSTQQLKGLVVSSDLKVEYEAKFDFDADSHGFeikkgvltNEAEHEvfapVALWLQALDSVLNTLEEQ-ELDFGRVNGISIAGQQHGSVYWSA 102
                 699***************99999988888777765432233445444555552221344666666666655555.5*********************99 PP

                 TTEES CS
      FGGY_N  88 ndkpL 92 
                 + + L
  EEA21399.1 103 DAERL 107
                 88665 PP

  == domain 2  score: 45.4 bits;  conditional E-value: 8e-16
                 TT--TTHHHHHHHHH.TTCHCCHHHHHSS-SSTTSHHHHHHHHHHHSCCHHCCHCEEEEHHHHHHHHHCT.--EEEHHHHCTTTSEETTTTEE-HHHHH CS
      FGGY_N  98 wkdrrtaeiveklke.egnekklyektglvlstgftlsklkWlkenepevfekiekflliddyLiwrLtg.qfvtdvtnasesmlfnikklewdeella 194
                 w+d  t+ ++++  + +g++++l+e tg+ ++  ft+  +  +++ +pe+++k+  + l++++L     g     d++++ +++l+nik + wd+ ll+
  EEA21399.1 133 WQDASTQRECDEFDAyLGGPEALAEVTGSKAHHRFTGPQILRFQRKYPEQYKKTSRISLVSSFLASLFLGsIAPFDISDVCGMNLWNIKAGSWDDGLLK 231
                 ******************************************************************999944568************************ PP

                 HT....T--GG..GS-EEE-.TCCEEEEEECCCCCCTT.S-EEEEEEEEEHHHHHHH CS
      FGGY_N 195 il....gipee..lLPklve.sseiigelkpelaaklGlkegvpvvggggDqqaaal 244
                 ++    g++    +L  + e ++   g+++++  +  ++++   +++ +gD+ ++ l
  EEA21399.1 232 LCagefGVDALkkKLGDVPEdGGLHLGKIHKYFVERYSFNPDCTIIPSTGDNPSTIL 288
                 972222344324589999762556789999999999999999999999999988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (571 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       301  (0.0167884); expected 358.6 (0.02)
Passed bias filter:                      294  (0.016398); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.69u 0.33s 00:00:01.02 Elapsed: 00:00:00.55
# Mc/sec: 3130.94
//
Query:       EEA21400.1  [L=1023]
Description: tRNA exportin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.2e-39  135.7   3.8    3.4e-39  134.3   0.0    3.4  5  Xpo1       Exportin 1-like protein
  ------ inclusion threshold ------
      0.036   14.3   0.0        6.7    7.3   0.0    4.0  3  HEAT       HEAT repeat
      0.062   13.4   0.0       0.16   12.1   0.0    1.6  1  Amidase_3  N-acetylmuramoyl-L-alanine amidase
       0.12   12.9   0.4         12    6.5   0.0    2.8  2  DUF4844    Domain of unknown function (DUF4844)


Domain annotation for each model (and alignments):
>> Xpo1  Exportin 1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  134.3   0.0   7.5e-43   3.4e-39       3     148 ..     104     268 ..     102     269 .. 0.92
   2 ?   -2.8   0.0       1.4   6.1e+03      99     116 ..     348     365 ..     285     398 .. 0.56
   3 ?   -1.8   0.1      0.63   2.8e+03      83      96 ..     375     388 ..     314     433 .. 0.64
   4 ?   -2.9   0.0       1.5   6.6e+03      24      51 ..     777     803 ..     770     815 .. 0.77
   5 ?   -0.2   0.0       0.2   9.1e+02      69     119 ..     860     891 ..     831     924 .. 0.61

  Alignments for each domain:
  == domain 1  score: 134.3 bits;  conditional E-value: 7.5e-43
                 HHHHHHHHHHHHHHHHHTTTTSTTHHHHHHHHHCT.........HHHHHHHHHHHHHHHHHHHT..SHTTTSCHHHHHHHHHHHHHH.HHHHHHHHHHH CS
        Xpo1   3 flrnklaealaelflqeypnnWpsffddllsllsss........psglelllriLkvlpeEiad..fsrskleqerrndlkdllrsn.vqkilelllqi 90 
                 +++nk+a+++++lf ++y + W++ffddllsl++++        p g+ ++lr+  ++++Ei+d  + rs++eqe++n lkdl+r++ +qki+ ++++i
  EEA21400.1 104 AIQNKIAQTVTYLFSALYAAGWETFFDDLLSLTTTDpstnlrnnPLGVVFYLRVVYSVHDEIGDvlVPRSREEQEKANTLKDLIRQRdIQKIAGSWQEI 202
                 69*********************************999************************************************************* PP

                 HHHHHHCCHHHHHHHHHHHHHHHHTTTS-HHHHHTSCHHHHHHHHC...CSCCC..........HHHHHHH CS
        Xpo1  91 leqsqskkqsselveavLkclsswvswidiglivnnpllnllfqlL...sdpel..........reaavec 148
                 l+q+q+++  +++ve++L++++ wvswidigl+vn+++l+llf+ L   +              r+aa+++
  EEA21400.1 203 LSQWQEGN--DQIVEMSLRAIGTWVSWIDIGLVVNQTMLDLLFRQLsraQ---KselrdgeekvRDAAIDV 268
                 ******87..************************************5552...433355555558888876 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1.4
                 HHHHHHHHHHHHHHHHTT CS
        Xpo1  99 qsselveavLkclsswvs 116
                 + ++l+++ L  + +++s
  EEA21400.1 348 KANSLLQSFLAHVLRFFS 365
                 334444444444444433 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 0.63
                 HHHHHHHHHHHHHH CS
        Xpo1  83 ilelllqileqsqs 96 
                 i+ +++++l++s++
  EEA21400.1 375 IIPCVTELLSYSRK 388
                 33333333333222 PP

  == domain 4  score: -2.9 bits;  conditional E-value: 1.5
                 STTHHHHHHHHHCT.HHHHHHHHHHHHH CS
        Xpo1  24 WpsffddllsllssspsglelllriLkv 51 
                  p ++d ll  +ss+++ + l+lr+L  
  EEA21400.1 777 LPRWIDGLLTETSSKDE-MALFLRLLDQ 803
                 57788999999998555.6699998865 PP

  == domain 5  score: -0.2 bits;  conditional E-value: 0.2
                 HHHHHHHHHHH.HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHTTTS- CS
        Xpo1  69 rndlkdllrsn.vqkilelllqileqsqskkqsselveavLkclsswvswid 119
                 +ndl   l s+  q i+e++++ +                    + +v+ id
  EEA21400.1 860 NNDLGSVLVSQaNQPIFESVISTI--------------------EHFVKDID 891
                 333344444443444444444444....................44444443 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   0.0    0.0015       6.7       9      28 ..     254     273 ..     248     275 .. 0.89
   2 ?   -1.4   0.0      0.92   4.1e+03       3      29 ..     358     384 ..     356     386 .. 0.73
   3 ?    1.7   0.0     0.091   4.1e+02       2      29 ..     564     591 ..     563     593 .. 0.88

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0015
                 HT-SSHHHHHHHHHHHHHHH CS
        HEAT   9 lsDpspeVReaAakaLgala 28 
                 l+D + +VR+aA+  +++++
  EEA21400.1 254 LRDGEEKVRDAAIDVFTEIV 273
                 799*************9997 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.92
                 HHHHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   3 PlllkllsDpspeVReaAakaLgalae 29 
                  ++l+  sD+  e+ ++ + ++++l++
  EEA21400.1 358 AHVLRFFSDDYDEICSTIIPCVTELLS 384
                 567777788888888888888887776 PP

  == domain 3  score: 1.7 bits;  conditional E-value: 0.091
                 HHHHHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   2 lPlllkllsDpspeVReaAakaLgalae 29 
                 l  +l+  ++p  +VR  + + + +l++
  EEA21400.1 564 LENFLQFAHHPMERVRTRSWYLFYRLVK 591
                 77899999*************9999997 PP

>> Amidase_3  N-acetylmuramoyl-L-alanine amidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   3.5e-05      0.16      43     112 ..     663     734 ..     659     761 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 3.5e-05
   Amidase_3  43 eVvltrdd.d.ksvslkeranianksradlfvsiHadsaanss.asGvevfyleknekkaeskrlaksiqkel 112
                 +Vv+ r+  + ++v++++  ++a++++  + ++iH+d +a ++ a+G++ ++   ++ ++ + +++ +i +++
  EEA21400.1 663 QVVYARSVmNpVFVDMENNLALAKSNDERAQLQIHHDIMALGTlARGFSDWT-PGSQMANPAAKFSPEISDAF 734
                 67777766434899***********************99999989******9.44555555555555555555 PP

>> DUF4844  Domain of unknown function (DUF4844)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.1     0.024   1.1e+02      28      90 ..     311     373 ..     287     380 .. 0.84
   2 ?    6.5   0.0    0.0026        12      30      92 ..     430     491 ..     405     497 .. 0.87

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.024
     DUF4844  28 gasddklrvalekkiNevakklleavsenlteeklqkklkltlerldkqylelDtEdrerild 90 
                    d  l  ++ k +N+ + +++ a  ++      ++k +  l+ + +  l + ++d + i++
  EEA21400.1 311 SKYDTDLAETVAKLVNITVVDIVRALDNDAVVVTTKEKANSLLQSFLAHVLRFFSDDYDEICS 373
                 5567788889999***************98877777777777788888888888999999997 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0026
     DUF4844  30 sddklrvalekkiNevakklleavsenlteeklqkklkltlerldkqylelDtEdrerildYm 92 
                 ++++  ++l+k +N++ +++++a +e l  + l++ + +t ++l ++ +++D  d +++l+ m
  EEA21400.1 430 TEEAEFQELRKRLNNL-QQIIAAANEGLYIDALSEVVGTTFQNLRQSGGQMDWRDLDLALHEM 491
                 5667778999999996.79**************************************999855 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1023 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       834  (0.0465168); expected 358.6 (0.02)
Passed bias filter:                      680  (0.0379274); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.85u 0.32s 00:00:01.17 Elapsed: 00:00:00.51
# Mc/sec: 6091.95
//
Query:       EEA21401.1  [L=288]
Description: esterase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      6e-50  170.2   0.0    7.4e-50  169.9   0.0    1.0  1  Esterase         Putative esterase
    7.2e-07   28.9   0.0    4.9e-05   22.9   0.0    2.1  2  Esterase_phd     Esterase PHB depolymerase
    1.8e-06   27.6   0.1    3.2e-06   26.8   0.1    1.4  1  Peptidase_S9     Prolyl oligopeptidase family
    0.00029   20.2   0.0     0.0012   18.1   0.0    1.9  3  Hydrolase_4      Serine aminopeptidase, S33
     0.0013   18.6   0.0      0.002   18.0   0.0    1.3  1  Abhydrolase_2    Phospholipase/Carboxylesterase
  ------ inclusion threshold ------
      0.011   14.4   0.0      0.016   13.9   0.0    1.2  1  AXE1             Acetyl xylan esterase (AXE1)
      0.012   15.4   0.0      0.041   13.7   0.0    1.9  1  Abhydrolase_3    alpha/beta hydrolase fold
      0.027   13.4   0.0      0.052   12.5   0.0    1.6  1  Chlorophyllase2  Chlorophyllase enzyme
      0.043   14.4   0.2      0.098   13.3   0.2    1.6  1  Abhydrolase_6    Alpha/beta hydrolase family
      0.087   12.5   0.0        0.1   12.2   0.0    1.4  1  Abhydrolase_1    alpha/beta hydrolase fold
        0.1   12.5   0.0       0.17   11.7   0.0    1.3  1  Lipase_3         Lipase (class 3)
       0.11   13.4   0.0       0.18   12.6   0.0    1.3  1  Rotamase_2       PPIC-type PPIASE domain
       0.11   11.0   0.0       0.23    9.9   0.0    1.5  2  PAF-AH_p_II      Platelet-activating factor acetylhydrolase, 
       0.11   12.1   0.6        2.4    7.8   0.3    2.5  3  Lambda_Kil       Bacteriophage lambda Kil protein
       0.17   10.9   0.0       0.36    9.8   0.0    1.5  2  Chlorophyllase   Chlorophyllase
        0.2   11.3   0.0       0.28   10.9   0.0    1.2  1  PGAP1            PGAP1-like protein


Domain annotation for each model (and alignments):
>> Esterase  Putative esterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  169.9   0.0   6.6e-53   7.4e-50       3     236 ..      25     279 ..      23     285 .. 0.95

  Alignments for each domain:
  == domain 1  score: 169.9 bits;  conditional E-value: 6.6e-53
                 TTTEEEEEEEEE.CC.GGTTTEEEEEEE--TTHHCCHHHHHCHHCCCCHCCT.EEEEEECCCSS-TTTT.TSBTTSB..B.TTEEETTCCCCCCHC..H CS
    Esterase   3 algreikvqvyLPedyspgrkypvvylldGltgwdqnfrakelleslaregeiaeviivvvprggessf.ysdwdlg..arfyenategpgaeaye..t 96 
                 ++ +e+ +++yLP++ ++++k p++++l+Glt++ +n + k ++++ a++++ia+  ++++prg   +  ++ +d+g  a+fy++at  p+ + y   +
  EEA21401.1  25 TTSCEMSFNLYLPPQ-AAEKKVPLLIYLSGLTCTAENCSEKGFFQHGASQRGIAVLYPDTSPRGLGIQGeDDAYDFGsgAGFYVDATLPPYDKGYNmyS 122
                 678************.************************************************887776999***********************9** PP

                 HHHTHHHHHHHHHCSEECCC..EEEEEETHHHHHHHHHHHCSTTTCCEEEEES--S-CCHCHHHC...........TTCCHHHCC-CCCCHCHHCHTTS CS
    Esterase  97 fltqeLlplldanfrtapdg..ravaGqSmGGlgALilalkhpdrFgsvssfSpivnpsnamWgq...........eekeawqendpvllakelsaslk 182
                 ++t+eL+ ++ + f+ + d+   +++G+SmGG+gAL+l l++p++++svs+f+pi np n++Wgq           + +e+w+e+d++ l+k+    + 
  EEA21401.1 123 YITEELPATVFEAFKYQIDAerVSITGHSMGGHGALTLFLRNPGKYKSVSAFAPITNPINCPWGQkafkgyfgsdaAAQEKWKEHDATELVKK--WTSG 219
                 **********999888777777******************************************************9**************86..8889 PP

                 EEEEEEEECTTBCCCHT.SCHHHHHHHHHHHCCHHHHCCCCCCTT-SCCCC......--SS CS
    Esterase 183 alriyldvGtseddlge.qlsveilevlarnrelkeqlaargvegedheyd......Gghs 236
                  l +++dvGt+++++++ ql +e+++ +a+++  +  +++r+++ +dh+y+      G+h 
  EEA21401.1 220 PLNVLIDVGTGDNFYKQgQLLPENFAKAAEEAGVQ-GVQIRYQPDYDHSYYtmatfaGDHV 279
                 9*************************999999999.9**************8888877776 PP

>> Esterase_phd  Esterase PHB depolymerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.0   4.3e-08   4.9e-05       2      57 ..      31      86 ..      30      92 .. 0.94
   2 ?    3.8   0.0      0.03        34      91     127 ..     137     173 ..     128     181 .. 0.87

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 4.3e-08
  Esterase_phd  2 ayrlylppGarrgamplvvmlhGctqsveefaaGtrmnlladklGvvvlypeqslr 57
                  +++lylpp a    +pl++ l G t ++e+ ++   ++  a + G++vlyp+ s r
    EEA21401.1 31 SFNLYLPPQAAEKKVPLLIYLSGLTCTAENCSEKGFFQHGASQRGIAVLYPDTSPR 86
                  689*****99999***************************************9977 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.03
  Esterase_phd  91 ehrvdaarvyvaGlsaGaaladllalhypdvfaaval 127
                   ++++da rv ++G s G+  a  l l  p ++ +v+ 
    EEA21401.1 137 KYQIDAERVSITGHSMGGHGALTLFLRNPGKYKSVSA 173
                   5789**************9999999999999988865 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.1   2.9e-09   3.2e-06      58     204 ..     137     285 ..     129     288 .] 0.75

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 2.9e-09
                   TTS--GGGEEEEEETHHHHHHHHHHHH-GGG-SEEEEESE---CCCHHCSTTSTHHHCCCC--TTTCHHHHHHHHHH-CGGG--....---EEEEEE CS
  Peptidase_S9  58 egyvdserlaitGgSyGGyltgaalnqrpdlFkaavaevpvvdvlrydsdtdllteeymewgnpeeneegykelspyspldnvk....aypplLlih 150
                   ++++d+er+ itG+S GG  ++++  ++p ++k + a +p+++ ++    +++++  +    ++   +e+ ke  + + +   k       ++L+ +
    EEA21401.1 137 KYQIDAERVSITGHSMGGHGALTLFLRNPGKYKSVSAFAPITNPINCPWGQKAFKGYFGSDAAA---QEKWKEHDATELV---KkwtsGPLNVLIDV 227
                   4589*******************************************99976665533333333...3323333333333...2233477789999* PP

                   ETT-SSS-THH..HHHHHHHHH--S-S.EEEEEETTS-SSTTSSHHHH.HHHHHHHHH CS
  Peptidase_S9 151 GlaDdrvppae..alklvaaLqkkgkn.vlllifpdegHgvgkprakv.eelarllaF 204
                   G+ D+     +  ++ +++a +++g++ v++++ pd +H++++  + + + +++ +++
    EEA21401.1 228 GTGDNFYKQGQllPENFAKAAEEAGVQgVQIRYQPDYDHSYYTMATFAgDHVEHAAKY 285
                   ****988776644679***********************8776554444666665555 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0         2   2.3e+03     185     227 ..      38      80 ..      35      83 .. 0.68
   2 !   18.1   0.0   1.1e-06    0.0012      65     114 ..     132     181 ..     118     197 .. 0.81
   3 ?   -2.5   0.0       2.3   2.5e+03     191     232 ..     217     266 ..     199     268 .. 0.68

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 2
  Hydrolase_4 185 eraakitlPllllhGeaDkvvdpeasrelyerlgskdktlkly 227
                   +aa+ ++Pll++ ++     ++   + ++++ +s++    ly
   EEA21401.1  38 PQAAEKKVPLLIYLSGLTCTAENCSEKGFFQHGASQRGIAVLY 80 
                  5788889999998887766666666666776666666555555 PP

  == domain 2  score: 18.1 bits;  conditional E-value: 1.1e-06
  Hydrolase_4  65 fvekvkeehpelplfllGhSmGGliallyllrypdkvaglilsaPalkik 114
                  ++e++k +   +++ + GhSmGG  al+++lr+p k++ +  +aP  ++ 
   EEA21401.1 132 VFEAFKYQIDAERVSITGHSMGGHGALTLFLRNPGKYKSVSAFAPITNPI 181
                  556666666667899************************99999997654 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 2.3
  Hydrolase_4 191 t...lPllllhGeaDkvvdpeas.....relyerlgskdktlklypglyH 232
                  t   l +l+  G+ D+  ++++      ++++e++g + +++++ p   H
   EEA21401.1 217 TsgpLNVLIDVGTGDNFYKQGQLlpenfAKAAEEAGVQGVQIRYQPDYDH 266
                  44445577778888888876555776667777777777777777777666 PP

>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   1.8e-06     0.002      86     137 ..     124     175 ..     105     191 .. 0.89

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 1.8e-06
                    HHHHHHHHHHHHHHTT--GGGEEEEEETHHHHHHHHHHHT-SS--SEEEEES CS
  Abhydrolase_2  86 saekleelidaelkkgipssriiigGFSqGaalalylaltlpkklggivafs 137
                    ++e+l +++ + +k+ i+++r+ i G S+G+  al l l  p k++ + af 
     EEA21401.1 124 ITEELPATVFEAFKYQIDAERVSITGHSMGGHGALTLFLRNPGKYKSVSAFA 175
                    6788899999*************************************99986 PP

>> AXE1  Acetyl xylan esterase (AXE1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   1.5e-05     0.016      73     189 ..      35     158 ..      28     176 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.5e-05
                 EEEES.SSSSEEEEEEEE-TT--GGGHHHHHHH....HHTT-EEEEEE-..TTTS..SSB-SSCCSS-SSSSTTTTTTS.TTT-HHHHHHHHHHHHHHH CS
        AXE1  73 lvlPkekeeklPavvefhGYegsrgeihdllny....aaaGyavvvmdv..RGqggesedkvgskgnkakGfiirGlld.keklyyrrvflDavrlvei 164
                 ++ P+++e+k+P+++   G + ++ + +++ ++    +  G+av+  d+  RG g + ed       +  Gf +   l   +k y    ++     + +
  EEA21401.1  35 YLPPQAAEKKVPLLIYLSGLTCTAENCSEKGFFqhgaSQRGIAVLYPDTspRGLGIQGEDDAYDF-GSGAGFYVDATLPpYDKGYNMYSYITEELPATV 132
                 678999***************99999999877622323579999988876689999999977777.677899999999867888877888888888888 PP

                 HHTST.TEEEEEEEEEEETHHHHHHH CS
        AXE1 165 vaslp.evDeeRvavlGasqGGalal 189
                   +++ ++D eRv+++G+s GG  al
  EEA21401.1 133 FEAFKyQIDAERVSITGHSMGGHGAL 158
                 8888658**************85444 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   3.7e-05     0.041      49      97 ..     114     169 ..     110     270 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 3.7e-05
                    HHHHHHHHHHHHHTH......H.HHTETTCEEEEEEETHHHHHHHHHHHHHHHTT- CS
  Abhydrolase_3  49 vedalaalrwlaeqa......w.elgadpsrivlaGdSaGGnlaaavalrardege 97 
                    ++ ++++++++ e+       + ++++d++r+ + G S GG+ a+ + lr   + +
     EEA21401.1 114 YDKGYNMYSYITEELpatvfeAfKYQIDAERVSITGHSMGGHGALTLFLRNPGKYK 169
                    78999999999999899999855999****************99998887766533 PP

>> Chlorophyllase2  Chlorophyllase enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   4.6e-05     0.052      70     121 ..     121     174 ..      30     188 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 4.6e-05
  Chlorophyllase2  70 lnWlakgLesvlp..eevepdlsklalsgHSrGgktafalalgkaktslkfsal 121
                        +++++L  ++    + + d ++++++gHS Gg+ a+ l l +     ++sa 
       EEA21401.1 121 YSYITEELPATVFeaFKYQIDAERVSITGHSMGGHGALTLFLRNPGKYKSVSAF 174
                      55666666665552345677899******************9998844444443 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.2   8.7e-05     0.098      25      95 ..      74     176 ..      64     277 .. 0.55

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 8.7e-05
                    CTCEEEEE--..TTST..................S-GGCS--HHHC.HHH...HHHHCCTT............TTSEEEEEETCHHH..HHHHHHH CS
  Abhydrolase_6  25 agvhvlapDl..pGhG..................rsdpppldledl.adl...aalldelaa..........gggpvvlvGHSlGGa..lalaaap 84 
                    +g++vl pD   +G G                  +      +l+++   +   + + +el+a          ++ +v + GHS+GG+  l l+++ 
     EEA21401.1  74 RGIAVLYPDTspRGLGiqgeddaydfgsgagfyvD-----ATLPPYdKGYnmySYITEELPAtvfeafkyqiDAERVSITGHSMGGHgaLTLFLRN 164
                    44666666665555543322222222121222221.....222221211111122333333344445555778999*********76325555444 PP

                    CC...EE.EEES- CS
  Abhydrolase_6  85 la.lvvg.vlldp 95 
                          +  + +p
     EEA21401.1 165 PGkY-KSvSAFAP 176
                    4441.22244444 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   9.1e-05       0.1      63     108 ..     133     178 ..      46     242 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 9.1e-05
                    HHHHHHHCTTSSEEEEEETHHHHHHHHHHHHHGGGEEEEEEESECS CS
  Abhydrolase_1  63 ldrildalgddkltlvGhSmGGmialayaaeyperVkalvllgaid 108
                    +++++ + + +++ + GhSmGG  al++++++p + k++ + ++i+
     EEA21401.1 133 FEAFKYQIDAERVSITGHSMGGHGALTLFLRNPGKYKSVSAFAPIT 178
                    447777888889999*****************99999988777733 PP

>> Lipase_3  Lipase (class 3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00015      0.17      50      79 ..     123     157 ..      90     170 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00015
                 HHHHHHHH.HHHHTT....-EEEEEEEETHHHHHH CS
    Lipase_3  50 qvlkelkr.llekyp....eysivvtGHSLGgalA 79 
                  +++el   ++e+++      ++ +tGHS+Gg  A
  EEA21401.1 123 YITEELPAtVFEAFKyqidAERVSITGHSMGGHGA 157
                 33333333233333333335789********9766 PP

>> Rotamase_2  PPIC-type PPIASE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   0.00016      0.18      35      90 ..     197     256 ..     194     270 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 0.00016
  Rotamase_2  35 aaeaalalakagaekdfaalakgnskkaadlg....ifesasnlpeelakaafalkpgev 90 
                 +a+a++++ +++a + ++++ +g  +   d+g    ++++ + lpe++akaa ++++ +v
  EEA21401.1 197 DAAAQEKWKEHDATELVKKWTSGPLNVLIDVGtgdnFYKQGQLLPENFAKAAEEAGVQGV 256
                 56677777777899*********9988555555556*****************9998877 PP

>> PAF-AH_p_II  Platelet-activating factor acetylhydrolase, isoform II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       1.5   1.7e+03      89     110 ..      31      55 ..      11      59 .. 0.63
   2 ?    9.9   0.0    0.0002      0.23     218     243 ..     133     158 ..     115     182 .. 0.83

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 1.5
                  EET--B--S...S-EEEEEEE--TT CS
  PAF-AH_p_II  89 kknellktk...ekyPlivFsHGLg 110
                  + n  l ++   +k Pl+++  GL 
   EEA21401.1  31 SFNLYLPPQaaeKKVPLLIYLSGLT 55 
                  3444444444435699999998886 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.0002
                  GGGGTT-EEEEEEEEEEETHHHHHHH CS
  PAF-AH_p_II 218 lqqlKdnldtskvaviGHsFGgAtvi 243
                  ++ +K ++d ++v++ GHs Gg  ++
   EEA21401.1 133 FEAFKYQIDAERVSITGHSMGGHGAL 158
                  7899*****************98766 PP

>> Lambda_Kil  Bacteriophage lambda Kil protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   0.3    0.0021       2.4       6      19 ..       1      14 [.       1      15 [. 0.91
   2 ?   -3.8   0.0       9.1     1e+04      27      35 ..     209     217 ..     207     218 .. 0.74
   3 ?    1.5   0.0      0.21   2.3e+02      12      20 ..     269     277 ..     266     279 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0021
  Lambda_Kil  6 rAiQsKavIArFlG 19
                +A+ +Ka+IA F G
  EEA21401.1  1 MAVTTKATIASFGG 14
                9**********955 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 9.1
  Lambda_Kil  27 AvdayKkav 35 
                 A +  Kk+ 
  EEA21401.1 209 ATELVKKWT 217
                 777789996 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.21
  Lambda_Kil  12 avIArFlGD 20 
                 ++ A+F GD
  EEA21401.1 269 YTMATFAGD 277
                 799*****9 PP

>> Chlorophyllase  Chlorophyllase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       3.4   3.8e+03      54     213 ..      53      68 ..      25      79 .. 0.54
   2 ?    9.8   0.0   0.00032      0.36     115     141 ..     138     164 ..     111     181 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 3.4
  Chlorophyllase  54 GtllsnkfyskllnhiashGfivvaPqlykllpPsaqdeidsaaevieWlseglkavlptsveanlsklalvGhsrGGktafalalgysseltfs 148
                     G                                                                                              
      EEA21401.1  53 GL--------------------------------------------------------------------------------------------- 54 
                     22............................................................................................. PP

  Chlorophyllase 149 aliGvdPvaGtskdkrtdPsvltykpnsfnleiPvtviGsGlGlavnnlliacaPegvnheefyk 213
                                                                        +c+ e+ + + f++
      EEA21401.1  55 ---------------------------------------------------TCTAENCSEKGFFQ 68 
                     ...................................................34444444444444 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00032
  Chlorophyllase 115 veanlsklalvGhsrGGktafalalgy 141
                      + + ++++++Ghs GG+ a++l l+ 
      EEA21401.1 138 YQIDAERVSITGHSMGGHGALTLFLRN 164
                     3457799***************99965 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00025      0.28      89     132 ..     141     184 ..     122     226 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00025
       PGAP1  89 eptsviliGHSmGGivaraaltlknyikqsvntiltlasPhalp 132
                 + ++v + GHSmGG  a +++  +  + +sv+    +  P++ p
  EEA21401.1 141 DAERVSITGHSMGGHGALTLFLRNPGKYKSVSAFAPITNPINCP 184
                 56899**********99777776667777777777777776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (288 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       366  (0.0204139); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              16  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 1961.02
//
Query:       EEA21402.1  [L=288]
Description: esterase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      6e-50  170.2   0.0    7.4e-50  169.9   0.0    1.0  1  Esterase         Putative esterase
    7.2e-07   28.9   0.0    4.9e-05   22.9   0.0    2.1  2  Esterase_phd     Esterase PHB depolymerase
    1.8e-06   27.6   0.1    3.2e-06   26.8   0.1    1.4  1  Peptidase_S9     Prolyl oligopeptidase family
    0.00029   20.2   0.0     0.0012   18.1   0.0    1.9  3  Hydrolase_4      Serine aminopeptidase, S33
     0.0013   18.6   0.0      0.002   18.0   0.0    1.3  1  Abhydrolase_2    Phospholipase/Carboxylesterase
  ------ inclusion threshold ------
      0.011   14.4   0.0      0.016   13.9   0.0    1.2  1  AXE1             Acetyl xylan esterase (AXE1)
      0.012   15.4   0.0      0.041   13.7   0.0    1.9  1  Abhydrolase_3    alpha/beta hydrolase fold
      0.027   13.4   0.0      0.052   12.5   0.0    1.6  1  Chlorophyllase2  Chlorophyllase enzyme
      0.043   14.4   0.2      0.098   13.3   0.2    1.6  1  Abhydrolase_6    Alpha/beta hydrolase family
      0.087   12.5   0.0        0.1   12.2   0.0    1.4  1  Abhydrolase_1    alpha/beta hydrolase fold
        0.1   12.5   0.0       0.17   11.7   0.0    1.3  1  Lipase_3         Lipase (class 3)
       0.11   13.4   0.0       0.18   12.6   0.0    1.3  1  Rotamase_2       PPIC-type PPIASE domain
       0.11   11.0   0.0       0.23    9.9   0.0    1.5  2  PAF-AH_p_II      Platelet-activating factor acetylhydrolase, 
       0.11   12.1   0.6        2.4    7.8   0.3    2.5  3  Lambda_Kil       Bacteriophage lambda Kil protein
       0.17   10.9   0.0       0.36    9.8   0.0    1.5  2  Chlorophyllase   Chlorophyllase
        0.2   11.3   0.0       0.28   10.9   0.0    1.2  1  PGAP1            PGAP1-like protein


Domain annotation for each model (and alignments):
>> Esterase  Putative esterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  169.9   0.0   6.6e-53   7.4e-50       3     236 ..      25     279 ..      23     285 .. 0.95

  Alignments for each domain:
  == domain 1  score: 169.9 bits;  conditional E-value: 6.6e-53
                 TTTEEEEEEEEE.CC.GGTTTEEEEEEE--TTHHCCHHHHHCHHCCCCHCCT.EEEEEECCCSS-TTTT.TSBTTSB..B.TTEEETTCCCCCCHC..H CS
    Esterase   3 algreikvqvyLPedyspgrkypvvylldGltgwdqnfrakelleslaregeiaeviivvvprggessf.ysdwdlg..arfyenategpgaeaye..t 96 
                 ++ +e+ +++yLP++ ++++k p++++l+Glt++ +n + k ++++ a++++ia+  ++++prg   +  ++ +d+g  a+fy++at  p+ + y   +
  EEA21402.1  25 TTSCEMSFNLYLPPQ-AAEKKVPLLIYLSGLTCTAENCSEKGFFQHGASQRGIAVLYPDTSPRGLGIQGeDDAYDFGsgAGFYVDATLPPYDKGYNmyS 122
                 678************.************************************************887776999***********************9** PP

                 HHHTHHHHHHHHHCSEECCC..EEEEEETHHHHHHHHHHHCSTTTCCEEEEES--S-CCHCHHHC...........TTCCHHHCC-CCCCHCHHCHTTS CS
    Esterase  97 fltqeLlplldanfrtapdg..ravaGqSmGGlgALilalkhpdrFgsvssfSpivnpsnamWgq...........eekeawqendpvllakelsaslk 182
                 ++t+eL+ ++ + f+ + d+   +++G+SmGG+gAL+l l++p++++svs+f+pi np n++Wgq           + +e+w+e+d++ l+k+    + 
  EEA21402.1 123 YITEELPATVFEAFKYQIDAerVSITGHSMGGHGALTLFLRNPGKYKSVSAFAPITNPINCPWGQkafkgyfgsdaAAQEKWKEHDATELVKK--WTSG 219
                 **********999888777777******************************************************9**************86..8889 PP

                 EEEEEEEECTTBCCCHT.SCHHHHHHHHHHHCCHHHHCCCCCCTT-SCCCC......--SS CS
    Esterase 183 alriyldvGtseddlge.qlsveilevlarnrelkeqlaargvegedheyd......Gghs 236
                  l +++dvGt+++++++ ql +e+++ +a+++  +  +++r+++ +dh+y+      G+h 
  EEA21402.1 220 PLNVLIDVGTGDNFYKQgQLLPENFAKAAEEAGVQ-GVQIRYQPDYDHSYYtmatfaGDHV 279
                 9*************************999999999.9**************8888877776 PP

>> Esterase_phd  Esterase PHB depolymerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.0   4.3e-08   4.9e-05       2      57 ..      31      86 ..      30      92 .. 0.94
   2 ?    3.8   0.0      0.03        34      91     127 ..     137     173 ..     128     181 .. 0.87

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 4.3e-08
  Esterase_phd  2 ayrlylppGarrgamplvvmlhGctqsveefaaGtrmnlladklGvvvlypeqslr 57
                  +++lylpp a    +pl++ l G t ++e+ ++   ++  a + G++vlyp+ s r
    EEA21402.1 31 SFNLYLPPQAAEKKVPLLIYLSGLTCTAENCSEKGFFQHGASQRGIAVLYPDTSPR 86
                  689*****99999***************************************9977 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.03
  Esterase_phd  91 ehrvdaarvyvaGlsaGaaladllalhypdvfaaval 127
                   ++++da rv ++G s G+  a  l l  p ++ +v+ 
    EEA21402.1 137 KYQIDAERVSITGHSMGGHGALTLFLRNPGKYKSVSA 173
                   5789**************9999999999999988865 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.1   2.9e-09   3.2e-06      58     204 ..     137     285 ..     129     288 .] 0.75

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 2.9e-09
                   TTS--GGGEEEEEETHHHHHHHHHHHH-GGG-SEEEEESE---CCCHHCSTTSTHHHCCCC--TTTCHHHHHHHHHH-CGGG--....---EEEEEE CS
  Peptidase_S9  58 egyvdserlaitGgSyGGyltgaalnqrpdlFkaavaevpvvdvlrydsdtdllteeymewgnpeeneegykelspyspldnvk....aypplLlih 150
                   ++++d+er+ itG+S GG  ++++  ++p ++k + a +p+++ ++    +++++  +    ++   +e+ ke  + + +   k       ++L+ +
    EEA21402.1 137 KYQIDAERVSITGHSMGGHGALTLFLRNPGKYKSVSAFAPITNPINCPWGQKAFKGYFGSDAAA---QEKWKEHDATELV---KkwtsGPLNVLIDV 227
                   4589*******************************************99976665533333333...3323333333333...2233477789999* PP

                   ETT-SSS-THH..HHHHHHHHH--S-S.EEEEEETTS-SSTTSSHHHH.HHHHHHHHH CS
  Peptidase_S9 151 GlaDdrvppae..alklvaaLqkkgkn.vlllifpdegHgvgkprakv.eelarllaF 204
                   G+ D+     +  ++ +++a +++g++ v++++ pd +H++++  + + + +++ +++
    EEA21402.1 228 GTGDNFYKQGQllPENFAKAAEEAGVQgVQIRYQPDYDHSYYTMATFAgDHVEHAAKY 285
                   ****988776644679***********************8776554444666665555 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0         2   2.3e+03     185     227 ..      38      80 ..      35      83 .. 0.68
   2 !   18.1   0.0   1.1e-06    0.0012      65     114 ..     132     181 ..     118     197 .. 0.81
   3 ?   -2.5   0.0       2.3   2.5e+03     191     232 ..     217     266 ..     199     268 .. 0.68

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 2
  Hydrolase_4 185 eraakitlPllllhGeaDkvvdpeasrelyerlgskdktlkly 227
                   +aa+ ++Pll++ ++     ++   + ++++ +s++    ly
   EEA21402.1  38 PQAAEKKVPLLIYLSGLTCTAENCSEKGFFQHGASQRGIAVLY 80 
                  5788889999998887766666666666776666666555555 PP

  == domain 2  score: 18.1 bits;  conditional E-value: 1.1e-06
  Hydrolase_4  65 fvekvkeehpelplfllGhSmGGliallyllrypdkvaglilsaPalkik 114
                  ++e++k +   +++ + GhSmGG  al+++lr+p k++ +  +aP  ++ 
   EEA21402.1 132 VFEAFKYQIDAERVSITGHSMGGHGALTLFLRNPGKYKSVSAFAPITNPI 181
                  556666666667899************************99999997654 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 2.3
  Hydrolase_4 191 t...lPllllhGeaDkvvdpeas.....relyerlgskdktlklypglyH 232
                  t   l +l+  G+ D+  ++++      ++++e++g + +++++ p   H
   EEA21402.1 217 TsgpLNVLIDVGTGDNFYKQGQLlpenfAKAAEEAGVQGVQIRYQPDYDH 266
                  44445577778888888876555776667777777777777777777666 PP

>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   1.8e-06     0.002      86     137 ..     124     175 ..     105     191 .. 0.89

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 1.8e-06
                    HHHHHHHHHHHHHHTT--GGGEEEEEETHHHHHHHHHHHT-SS--SEEEEES CS
  Abhydrolase_2  86 saekleelidaelkkgipssriiigGFSqGaalalylaltlpkklggivafs 137
                    ++e+l +++ + +k+ i+++r+ i G S+G+  al l l  p k++ + af 
     EEA21402.1 124 ITEELPATVFEAFKYQIDAERVSITGHSMGGHGALTLFLRNPGKYKSVSAFA 175
                    6788899999*************************************99986 PP

>> AXE1  Acetyl xylan esterase (AXE1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   1.5e-05     0.016      73     189 ..      35     158 ..      28     176 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.5e-05
                 EEEES.SSSSEEEEEEEE-TT--GGGHHHHHHH....HHTT-EEEEEE-..TTTS..SSB-SSCCSS-SSSSTTTTTTS.TTT-HHHHHHHHHHHHHHH CS
        AXE1  73 lvlPkekeeklPavvefhGYegsrgeihdllny....aaaGyavvvmdv..RGqggesedkvgskgnkakGfiirGlld.keklyyrrvflDavrlvei 164
                 ++ P+++e+k+P+++   G + ++ + +++ ++    +  G+av+  d+  RG g + ed       +  Gf +   l   +k y    ++     + +
  EEA21402.1  35 YLPPQAAEKKVPLLIYLSGLTCTAENCSEKGFFqhgaSQRGIAVLYPDTspRGLGIQGEDDAYDF-GSGAGFYVDATLPpYDKGYNMYSYITEELPATV 132
                 678999***************99999999877622323579999988876689999999977777.677899999999867888877888888888888 PP

                 HHTST.TEEEEEEEEEEETHHHHHHH CS
        AXE1 165 vaslp.evDeeRvavlGasqGGalal 189
                   +++ ++D eRv+++G+s GG  al
  EEA21402.1 133 FEAFKyQIDAERVSITGHSMGGHGAL 158
                 8888658**************85444 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   3.7e-05     0.041      49      97 ..     114     169 ..     110     270 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 3.7e-05
                    HHHHHHHHHHHHHTH......H.HHTETTCEEEEEEETHHHHHHHHHHHHHHHTT- CS
  Abhydrolase_3  49 vedalaalrwlaeqa......w.elgadpsrivlaGdSaGGnlaaavalrardege 97 
                    ++ ++++++++ e+       + ++++d++r+ + G S GG+ a+ + lr   + +
     EEA21402.1 114 YDKGYNMYSYITEELpatvfeAfKYQIDAERVSITGHSMGGHGALTLFLRNPGKYK 169
                    78999999999999899999855999****************99998887766533 PP

>> Chlorophyllase2  Chlorophyllase enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   4.6e-05     0.052      70     121 ..     121     174 ..      30     188 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 4.6e-05
  Chlorophyllase2  70 lnWlakgLesvlp..eevepdlsklalsgHSrGgktafalalgkaktslkfsal 121
                        +++++L  ++    + + d ++++++gHS Gg+ a+ l l +     ++sa 
       EEA21402.1 121 YSYITEELPATVFeaFKYQIDAERVSITGHSMGGHGALTLFLRNPGKYKSVSAF 174
                      55666666665552345677899******************9998844444443 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.2   8.7e-05     0.098      25      95 ..      74     176 ..      64     277 .. 0.55

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 8.7e-05
                    CTCEEEEE--..TTST..................S-GGCS--HHHC.HHH...HHHHCCTT............TTSEEEEEETCHHH..HHHHHHH CS
  Abhydrolase_6  25 agvhvlapDl..pGhG..................rsdpppldledl.adl...aalldelaa..........gggpvvlvGHSlGGa..lalaaap 84 
                    +g++vl pD   +G G                  +      +l+++   +   + + +el+a          ++ +v + GHS+GG+  l l+++ 
     EEA21402.1  74 RGIAVLYPDTspRGLGiqgeddaydfgsgagfyvD-----ATLPPYdKGYnmySYITEELPAtvfeafkyqiDAERVSITGHSMGGHgaLTLFLRN 164
                    44666666665555543322222222121222221.....222221211111122333333344445555778999*********76325555444 PP

                    CC...EE.EEES- CS
  Abhydrolase_6  85 la.lvvg.vlldp 95 
                          +  + +p
     EEA21402.1 165 PGkY-KSvSAFAP 176
                    4441.22244444 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   9.1e-05       0.1      63     108 ..     133     178 ..      46     242 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 9.1e-05
                    HHHHHHHCTTSSEEEEEETHHHHHHHHHHHHHGGGEEEEEEESECS CS
  Abhydrolase_1  63 ldrildalgddkltlvGhSmGGmialayaaeyperVkalvllgaid 108
                    +++++ + + +++ + GhSmGG  al++++++p + k++ + ++i+
     EEA21402.1 133 FEAFKYQIDAERVSITGHSMGGHGALTLFLRNPGKYKSVSAFAPIT 178
                    447777888889999*****************99999988777733 PP

>> Lipase_3  Lipase (class 3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00015      0.17      50      79 ..     123     157 ..      90     170 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00015
                 HHHHHHHH.HHHHTT....-EEEEEEEETHHHHHH CS
    Lipase_3  50 qvlkelkr.llekyp....eysivvtGHSLGgalA 79 
                  +++el   ++e+++      ++ +tGHS+Gg  A
  EEA21402.1 123 YITEELPAtVFEAFKyqidAERVSITGHSMGGHGA 157
                 33333333233333333335789********9766 PP

>> Rotamase_2  PPIC-type PPIASE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   0.00016      0.18      35      90 ..     197     256 ..     194     270 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 0.00016
  Rotamase_2  35 aaeaalalakagaekdfaalakgnskkaadlg....ifesasnlpeelakaafalkpgev 90 
                 +a+a++++ +++a + ++++ +g  +   d+g    ++++ + lpe++akaa ++++ +v
  EEA21402.1 197 DAAAQEKWKEHDATELVKKWTSGPLNVLIDVGtgdnFYKQGQLLPENFAKAAEEAGVQGV 256
                 56677777777899*********9988555555556*****************9998877 PP

>> PAF-AH_p_II  Platelet-activating factor acetylhydrolase, isoform II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       1.5   1.7e+03      89     110 ..      31      55 ..      11      59 .. 0.63
   2 ?    9.9   0.0    0.0002      0.23     218     243 ..     133     158 ..     115     182 .. 0.83

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 1.5
                  EET--B--S...S-EEEEEEE--TT CS
  PAF-AH_p_II  89 kknellktk...ekyPlivFsHGLg 110
                  + n  l ++   +k Pl+++  GL 
   EEA21402.1  31 SFNLYLPPQaaeKKVPLLIYLSGLT 55 
                  3444444444435699999998886 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.0002
                  GGGGTT-EEEEEEEEEEETHHHHHHH CS
  PAF-AH_p_II 218 lqqlKdnldtskvaviGHsFGgAtvi 243
                  ++ +K ++d ++v++ GHs Gg  ++
   EEA21402.1 133 FEAFKYQIDAERVSITGHSMGGHGAL 158
                  7899*****************98766 PP

>> Lambda_Kil  Bacteriophage lambda Kil protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   0.3    0.0021       2.4       6      19 ..       1      14 [.       1      15 [. 0.91
   2 ?   -3.8   0.0       9.1     1e+04      27      35 ..     209     217 ..     207     218 .. 0.74
   3 ?    1.5   0.0      0.21   2.3e+02      12      20 ..     269     277 ..     266     279 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0021
  Lambda_Kil  6 rAiQsKavIArFlG 19
                +A+ +Ka+IA F G
  EEA21402.1  1 MAVTTKATIASFGG 14
                9**********955 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 9.1
  Lambda_Kil  27 AvdayKkav 35 
                 A +  Kk+ 
  EEA21402.1 209 ATELVKKWT 217
                 777789996 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.21
  Lambda_Kil  12 avIArFlGD 20 
                 ++ A+F GD
  EEA21402.1 269 YTMATFAGD 277
                 799*****9 PP

>> Chlorophyllase  Chlorophyllase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       3.4   3.8e+03      54     213 ..      53      68 ..      25      79 .. 0.54
   2 ?    9.8   0.0   0.00032      0.36     115     141 ..     138     164 ..     111     181 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 3.4
  Chlorophyllase  54 GtllsnkfyskllnhiashGfivvaPqlykllpPsaqdeidsaaevieWlseglkavlptsveanlsklalvGhsrGGktafalalgysseltfs 148
                     G                                                                                              
      EEA21402.1  53 GL--------------------------------------------------------------------------------------------- 54 
                     22............................................................................................. PP

  Chlorophyllase 149 aliGvdPvaGtskdkrtdPsvltykpnsfnleiPvtviGsGlGlavnnlliacaPegvnheefyk 213
                                                                        +c+ e+ + + f++
      EEA21402.1  55 ---------------------------------------------------TCTAENCSEKGFFQ 68 
                     ...................................................34444444444444 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00032
  Chlorophyllase 115 veanlsklalvGhsrGGktafalalgy 141
                      + + ++++++Ghs GG+ a++l l+ 
      EEA21402.1 138 YQIDAERVSITGHSMGGHGALTLFLRN 164
                     3457799***************99965 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00025      0.28      89     132 ..     141     184 ..     122     226 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00025
       PGAP1  89 eptsviliGHSmGGivaraaltlknyikqsvntiltlasPhalp 132
                 + ++v + GHSmGG  a +++  +  + +sv+    +  P++ p
  EEA21402.1 141 DAERVSITGHSMGGHGALTLFLRNPGKYKSVSAFAPITNPINCP 184
                 56899**********99777776667777777777777776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (288 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       366  (0.0204139); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              16  [number of targets reported over threshold]
# CPU time: 0.50u 0.29s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 1963.29
//
Query:       EEA21403.1  [L=2094]
Description: separin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.7e-154  514.7   0.0   4.8e-154  513.3   0.0    1.8  1  Peptidase_C50  Peptidase family C50
    0.00012   21.6   0.2    0.00092   18.7   0.0    2.5  3  CHAT           CHAT domain
  ------ inclusion threshold ------
       0.16   11.9   3.4        3.6    7.6   0.1    4.4  5  TPR_1          Tetratricopeptide repeat
       0.17   11.6   8.6        1.1    8.9   0.1    4.2  4  RPN7           26S proteasome subunit RPN7
       0.47   11.4   9.2        6.7    7.8   0.2    5.7  5  TPR_14         Tetratricopeptide repeat
       0.72   10.2  12.6       0.32   11.3   3.5    4.6  5  TPR_12         Tetratricopeptide repeat
          4    7.8  12.6         18    5.8   0.3    5.8  6  TPR_2          Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> Peptidase_C50  Peptidase family C50
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  513.3   0.0  1.9e-157  4.8e-154       2     395 .]    1620    2016 ..    1619    2016 .. 0.96

  Alignments for each domain:
  == domain 1  score: 513.3 bits;  conditional E-value: 1.9e-157
                     TSSEEEEEEEETTSTEEEEEEECCCCCC...HH....HHHHHHHHHHHHHHHHHHHHCHCCHHCCTHHHHHHHHHHHHHHHHHHHHHHHHHHTT CS
  Peptidase_C50    2 dkkdLllsrleagssplvlrlplerassrdadeevlsfeevkeelkeiieesnestksakdvktkeakkeWWkeReeLDkrLkeLleniekvwL 95  
                     d++++++sr+++gssp++lrlpl+r +++++de+ ++f+ +k+e+keii ++n+s+++ak+  +k++kk+WW++Re+LD+rL++Ll+n+e++wL
     EEA21403.1 1620 DRTEFIISRMSHGSSPFLLRLPLKRSEEDNQDEDDFTFDWGKNEMKEIIALANASAHDAKTRIDKNSKKQWWATRESLDRRLETLLDNMENIWL 1713
                     57899*********************9999999*************************99999******************************* PP

                     GGGGGGGS-E---HHHHHHHHHHHHHHHHHHSCHHHHSCHCCCCHTBTHHHHHHHHTCHTT..TTTHHHHHHHHHHHHHHHHHHTT....GGGS CS
  Peptidase_C50   96 ggfkgilsqeerekellekfqkkfekilkkhlpsrkqkkkekkklelddrllelflglgda..eedldeeledllyfvvdilqfhgernaydei 187 
                     ggf+gi+ +  r++++l++f+++fek+l+khlpsr+++k +k+k+++++++l+lf+gl d   +e+ ++++ dllyfvvdilqf+gernaydei
     EEA21403.1 1714 GGFRGIFDTFPRNSKVLTQFSSSFEKVLNKHLPSRRKSKDKKEKIKVHENVLSLFIGLRDLdkQENPEDSVLDLLYFVVDILQFQGERNAYDEI 1807
                     ***********************************************************999889999************************** PP

                     .HHHHHHHHHHHHHHHHCCHHHCE....SEEEEEE-TTCTTS-GGGSTTTTTS-EEEES-HHHHHHHHHHHCTT....GCSEEEESTSTEEEEE CS
  Peptidase_C50  188 dfdslvvellealkeyeeaakeekkkekehtiLvldkelqalPWEslpiLrgqsvsRvpSleslrellekskek....eegekvsksskgtyiL 277 
                     dfd++v+++l+ l++ +++  +e   + +htiL+ldk+l+++PWEslp+L+g  vsR+pSle+lr+++ + ++     +   +v+++ +g +iL
     EEA21403.1 1808 DFDMMVIDTLDILNSLHSTSPSE-LVRPNHTILILDKSLHSFPWESLPCLHGLPVSRMPSLECLRKRIIHFRSLvdssDVAFEVNRH-NGHFIL 1899
                     *****************977776.458*******************************************99875543333444555.8***** PP

                     -TTS-SHHHHHHHHHHHHHHCCT-EEEESS---HHHHHHHHHHSSEEEEESSTTSTTTS-HHHHTT.S--SEEEEESTTTT--ECTTTCECCSH CS
  Peptidase_C50  278 nPsgDLksTqetfeewleklekgwkgivgraPteeeleeaLkssdlflYfGHGsGaqYirsreirklercaatlLmGCSSgalkeaGefepsGt 371 
                     nPsgDLk+Tq+tfee l++  +gw+ ++gr+P+eee+++ L+++d+flYfGHGsGaqYir+r+i++l+rca+++LmGCSSg l+eaGe+ep+Gt
     EEA21403.1 1900 NPSGDLKTTQSTFEEELAHR-EGWSAVIGRTPSEEEFKAGLEEKDIFLYFGHGSGAQYIRGRTIKRLDRCAVAFLMGCSSGCLAEAGELEPYGT 1992
                     *****************986.5************************************************************************ PP

                     HHHHHHTT-SEEEEESS--BHHHH CS
  Peptidase_C50  372 vlnYllagcpavvanLWDVTDkDI 395 
                     ++nY+ ag+pa+va+LWDVTDkDI
     EEA21403.1 1993 PMNYMQAGSPALVATLWDVTDKDI 2016
                     ***********************9 PP

>> CHAT  CHAT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.1       1.5   3.9e+03      56      93 ..     105     201 ..      83     302 .. 0.56
   2 ?   -1.7   0.0      0.59   1.5e+03      26      44 ..    1836    1854 ..    1824    1882 .. 0.86
   3 !   18.7   0.0   3.6e-07   0.00092     175     249 ..    1955    2027 ..    1918    2032 .. 0.87

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 1.5
                 xxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxx.......................................................x RF
        CHAT  56 avsyapsarllselrkaaasaasalq.....lvvgdpkfdaa.......................................................e 93 
                 +v  + s  +ls+  +++a ++s+lq      +v+ pk++                                                          
  EEA21403.1 105 EVFNTASK-ALSDALQRKAPSKSPLQptspnQLVSSPKKPSTkppkptptvngspennviataecailalttlrnlkgersskidsanlqleqgaciL 201
                 44444442.35555555555555555566665555555553334444444444444444555555555555555555555555555555555555542 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.59
                  xxxxxxxxxxxxxxxxxxx RF
        CHAT   26 qlvivpdgeLqliPfealv 44  
                  + ++++d+ L+++P+e l+
  EEA21403.1 1836 HTILILDKSLHSFPWESLP 1854
                  7789************875 PP

  == domain 3  score: 18.7 bits;  conditional E-value: 3.6e-07
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        CHAT  175 glLtaeeilelnldgaelVvLsACqtglgevidgegvlgLaralllaGarsviaslwpVddeatalLmkrfyqnl 249 
                  + ++++ i +  ld++ +++L  C +g     ++ + +g     ++aG+++++a+lw V d+   +++k  +q++
  EEA21403.1 1955 QYIRGRTIKR--LDRCAVAFLMGCSSGCLAEAGELEPYGTPMNYMQAGSPALVATLWDVTDKDIDRFAKSTFQQW 2027
                  5566666666..7779***********88888999***********************************99987 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0      0.47   1.2e+03       4      24 ..     445     465 ..     442     470 .. 0.85
   2 ?   -2.1   0.0       1.6     4e+03       6      29 ..     714     737 ..     713     738 .. 0.91
   3 ?    7.6   0.1    0.0014       3.6       3      28 ..     996    1021 ..     994    1023 .. 0.90
   4 ?    0.4   0.1      0.25   6.5e+02      14      33 ..    1197    1216 ..    1195    1217 .. 0.88
   5 ?   -2.2   0.0       1.7   4.5e+03      12      27 ..    1275    1290 ..    1270    1290 .. 0.75

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.47
                 HHHHHHHHHHTT-HHHHHHHH CS
       TPR_1   4 lynlGnayfklgkydeAleyy 24 
                  y lG + ++   ++eAl++ 
  EEA21403.1 445 SYSLGKIAQEASCLKEALKHL 465
                 5899999999999*****997 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.6
                 HHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1   6 nlGnayfklgkydeAleyyekALe 29 
                 +l+++y+   +  + +  +e+ ++
  EEA21403.1 714 RLAHLYLDARMGAKSITSFERSIQ 737
                 7999***99999999*****9986 PP

  == domain 3  score: 7.6 bits;  conditional E-value: 0.0014
                  HHHHHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_1    3 alynlGnayfklgkydeAleyyekAL 28  
                  al + ++ y +lg+++ Al+  ++A 
  EEA21403.1  996 ALSRCALQYSRLGDHKAALDLLDRAK 1021
                  889999*****************995 PP

  == domain 4  score: 0.4 bits;  conditional E-value: 0.25
                  TT-HHHHHHHHHHHHHHSTT CS
       TPR_1   14 lgkydeAleyyekALelnPn 33  
                  +g +++A+ y e+AL++n++
  EEA21403.1 1197 NGLFQDAIYYGEQALKVNET 1216
                  68899************986 PP

  == domain 5  score: -2.2 bits;  conditional E-value: 1.7
                  HHTT-HHHHHHHHHHH CS
       TPR_1   12 fklgkydeAleyyekA 27  
                  +++g+y+e l    +A
  EEA21403.1 1275 RSQGNYKEVLRLLHEA 1290
                  689***9988776665 PP

>> RPN7  26S proteasome subunit RPN7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.1      0.19   4.8e+02      16      89 ..     423     494 ..     414     511 .. 0.72
   2 ?    3.0   0.5     0.029        73      20     105 ..     978    1067 ..     967    1119 .. 0.70
   3 ?    8.9   0.1   0.00043       1.1      44     140 ..    1192    1291 ..    1179    1300 .. 0.72
   4 ?   -0.1   0.0      0.25   6.4e+02      47      75 ..    1385    1413 ..    1375    1418 .. 0.87

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.19
                 HHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHCT-HHHHHHHHHTCCCC--SHHHHHHHHHHHHHHHHHTT-H CS
        RPN7  16 leeLdaelkdakenlgkeeirrakldlaehYlkigdleeAlkaysrireyctslkhkidmllnlirvaiffndw 89 
                 +++L++++ + + ++   +  +  + l++   ++  l+eAlk +s + e+ t+ +  + + l+  r+ai + ++
  EEA21403.1 423 VQRLQSRIAKCQMKGPTYSW-KVSYSLGKIAQEASCLKEALKHLSSVTEKITKED-PMALSLTQCRIAIVYLYM 494
                 55566666554433333333.3466789999999999**********99999855.577889999999887655 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.029
                  HHHHHHHHHTT-HHHHHHHHHHHHHHHHHCT-HHHHHHHHHTCCCC--SHHHH....HHHHHHHHHHHHHTT-HHHHHHHHHHHHCSSS- CS
        RPN7   20 daelkdakenlgkeeirrakldlaehYlkigdleeAlkaysrireyctslkhk....idmllnlirvaiffndwdlvskylekakellek 105 
                    ++ + +e   +++   a  + a  Y + gd++ Al ++ r+ + +t  +++    i   l+l + ++++n++d ++k l++ +el  +
  EEA21403.1  978 SLRIYEVQEARDSSSLILALSRCALQYSRLGDHKAALDLLDRAKQRVTIGEAScyaaITYQLALAEYNMEINNIDNAEKALQDGQELFRS 1067
                  555556666666677777777888889999**********99999998777651111444455555555555555555555555555544 PP

  == domain 3  score: 8.9 bits;  conditional E-value: 0.00043
                  HHHHHCT-HHHHHHHHHTCCCC--SHHHHHHHHHHHHHHHHHT...T-HHHHHHHHHHHHCSSS---.HHHHHHHHHHHHHHHHHTT-HHHHHHHHC CS
        RPN7   44 ehYlkigdleeAlkaysrireyctslkhkidmllnlirvaiff...ndwdlvskylekakellekggdwerknrlkvyeGlallairkfkeAaelll 137 
                  +  +  g ++ A+ + +++++   +l+ ++ +l +  ++++++   n    ++++l+ a ++ e   +     +lk++++ ++ +++++ke+ +ll+
  EEA21403.1 1192 RLSAYNGLFQDAIYYGEQALKVNETLGISVRLLTCQAELGLEWirgNHLIDAKTVLDAATKISEVLINSVETVKLKISQAALSRSQGNYKEVLRLLH 1288
                  55555566677777777777777777777777777777776542224444456677777777777777888999*********************** PP

                  TS- CS
        RPN7  138 dil 140 
                  +++
  EEA21403.1 1289 EAE 1291
                  987 PP

  == domain 4  score: -0.1 bits;  conditional E-value: 0.25
                  HHCT-HHHHHHHHHTCCCC--SHHHHHHH CS
        RPN7   47 lkigdleeAlkaysrireyctslkhkidm 75  
                  l + dl+ A ++++ +re c+s+   i++
  EEA21403.1 1385 LAVEDLDGASRLLKVVRESCSSMATQISI 1413
                  567899****************9999987 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.1       1.3   3.4e+03       6      30 ..     714     738 ..     712     745 .. 0.90
   2 ?    7.8   0.2    0.0026       6.7       4      27 ..     997    1020 ..     995    1027 .. 0.88
   3 ?    2.8   0.1      0.11   2.8e+02       4      30 ..    1038    1064 ..    1035    1070 .. 0.88
   4 ?   -0.6   0.0       1.3   3.3e+03      10      27 ..    1273    1290 ..    1266    1300 .. 0.81
   5 ?   -1.3   0.0       2.2   5.7e+03       5      25 ..    1378    1398 ..    1375    1399 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 1.3
      TPR_14   6 alaeallalGdpdeAiallrralal 30 
                 +la+++l ++  +++i+ ++r ++ 
  EEA21403.1 714 RLAHLYLDARMGAKSITSFERSIQE 738
                 69*******************9985 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0026
      TPR_14    4 llalaeallalGdpdeAiallrra 27  
                  l + a  + +lGd+++A++ll+ra
  EEA21403.1  997 LSRCALQYSRLGDHKAALDLLDRA 1020
                  5677999****************9 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.11
      TPR_14    4 llalaeallalGdpdeAiallrralal 30  
                  +lalae+ ++  + d A+++l++  +l
  EEA21403.1 1038 QLALAEYNMEINNIDNAEKALQDGQEL 1064
                  689999999*************98765 PP

  == domain 4  score: -0.6 bits;  conditional E-value: 1.3
      TPR_14   10 allalGdpdeAiallrra 27  
                  + + +G+++e ++ll++a
  EEA21403.1 1273 LSRSQGNYKEVLRLLHEA 1290
                  446799*******99998 PP

  == domain 5  score: -1.3 bits;  conditional E-value: 2.2
      TPR_14    5 lalaeallalGdpdeAiallr 25  
                  ++  +alla +d+d+A +ll+
  EEA21403.1 1378 RQQIHALLAVEDLDGASRLLK 1398
                  567899**********99985 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0       1.1   2.9e+03       8      55 ..     447     491 ..     444     497 .. 0.65
   2 ?   -2.7   0.1       2.9   7.5e+03       7      31 ..     713     737 ..     709     746 .. 0.83
   3 ?   11.3   3.5   0.00013      0.32       6      76 ..     997    1066 ..     972    1072 .. 0.78
   4 ?    0.4   0.0      0.32   8.3e+02      58      74 ..    1197    1213 ..    1188    1216 .. 0.81
   5 ?   -1.3   0.0       1.1   2.8e+03      10      29 ..    1271    1290 ..    1231    1293 .. 0.62

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 1.1
      TPR_12   8 nlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrly 55 
                  l+ + +++  + eAl++l  + e +++    d  +++ t++ ++++y
  EEA21403.1 447 SLGKIAQEASCLKEALKHLSSVTEKITKE---DPMALSLTQCRIAIVY 491
                 68888888889999999988775555433...3344555555555555 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 2.9
      TPR_12   7 nnlaavlrrlgrydeAlellekale 31 
                  +la++++ +   +++++ +e++++
  EEA21403.1 713 ERLAHLYLDARMGAKSITSFERSIQ 737
                 4799999999999999999999986 PP

  == domain 3  score: 11.3 bits;  conditional E-value: 0.00013
      TPR_12    6 lnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76  
                  l++ a+ + rlg++  Al+ll++a +++  + +   ++++t++ +L+++  + ++ + A+++l++  ++++
  EEA21403.1  997 LSRCALQYSRLGDHKAALDLLDRAKQRV-TIGEASCYAAITYQLALAEYNMEINNIDNAEKALQDGQELFR 1066
                  4455777889999999999999999999.354455566666666666666688999999999988777766 PP

  == domain 4  score: 0.4 bits;  conditional E-value: 0.32
      TPR_12   58 lgryeeAlelleealai 74  
                   g +++A+++ e+al++
  EEA21403.1 1197 NGLFQDAIYYGEQALKV 1213
                  57789999999999987 PP

  == domain 5  score: -1.3 bits;  conditional E-value: 1.1
      TPR_12   10 aavlrrlgrydeAlelleka 29  
                  aa+ r +g+y e l+ll++a
  EEA21403.1 1271 AALSRSQGNYKEVLRLLHEA 1290
                  33444455555555555544 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0      0.74   1.9e+03       4      24 ..     445     465 ..     442     470 .. 0.85
   2 ?   -0.3   0.0      0.62   1.6e+03       5      30 ..     713     738 ..     711     741 .. 0.89
   3 ?    5.8   0.3    0.0068        18       3      28 ..     996    1021 ..     994    1023 .. 0.91
   4 ?   -1.1   0.2       1.1   2.8e+03       6      30 ..    1040    1064 ..    1036    1067 .. 0.81
   5 ?    4.0   0.1     0.025        63      12      33 ..    1195    1216 ..    1192    1217 .. 0.88
   6 ?   -0.4   0.0      0.66   1.7e+03       8      27 ..    1271    1290 ..    1267    1291 .. 0.84

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.74
       TPR_2   4 lynlGlayyklgdyeeAleaf 24 
                  y lG+++ ++  ++eAl+++
  EEA21403.1 445 SYSLGKIAQEASCLKEALKHL 465
                 588999999999999**9997 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.62
       TPR_2   5 ynlGlayyklgdyeeAleafekAlel 30 
                  +l+ +y+ +   ++ +  fe++++ 
  EEA21403.1 713 ERLAHLYLDARMGAKSITSFERSIQE 738
                 68999*****************9986 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.0068
       TPR_2    3 alynlGlayyklgdyeeAleafekAl 28  
                  al + +l y +lgd++ Al+++++A 
  EEA21403.1  996 ALSRCALQYSRLGDHKAALDLLDRAK 1021
                  789999*****************995 PP

  == domain 4  score: -1.1 bits;  conditional E-value: 1.1
       TPR_2    6 nlGlayyklgdyeeAleafekAlel 30  
                  +l++  ++ ++ + A++a++   el
  EEA21403.1 1040 ALAEYNMEINNIDNAEKALQDGQEL 1064
                  7889999999999999999976666 PP

  == domain 5  score: 4.0 bits;  conditional E-value: 0.025
       TPR_2   12 yklgdyeeAleafekAleldPn 33  
                  +++g +++A+ + e+Al+ +++
  EEA21403.1 1195 AYNGLFQDAIYYGEQALKVNET 1216
                  67899*************9976 PP

  == domain 6  score: -0.4 bits;  conditional E-value: 0.66
       TPR_2    8 GlayyklgdyeeAleafekA 27  
                  + + + +g+y+e l+++ +A
  EEA21403.1 1271 AALSRSQGNYKEVLRLLHEA 1290
                  5666789*****99999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2094 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       967  (0.053935); expected 358.6 (0.02)
Passed bias filter:                      505  (0.0281667); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 1.12u 0.34s 00:00:01.46 Elapsed: 00:00:00.54
# Mc/sec: 11752.46
//
Query:       EEA21404.1  [L=217]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-60  203.1   2.7    2.1e-60  202.8   2.7    1.1  1  DUF5321   Family of unknown function (DUF5321)
  ------ inclusion threshold ------
      0.083   14.0   2.5       0.13   13.3   2.5    1.3  1  MRI       Modulator of retrovirus infection


Domain annotation for each model (and alignments):
>> DUF5321  Family of unknown function (DUF5321)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  202.8   2.7   2.4e-64   2.1e-60       4     152 ..      45     191 ..      42     201 .. 0.90

  Alignments for each domain:
  == domain 1  score: 202.8 bits;  conditional E-value: 2.4e-64
     DUF5321   4 essslprvaqpsfWkslipkplrkesaskakkkkkkkkewnpatffiviflLiGSqairmialknefaaytrkadakielLreviekvqrGEevdvekl 102
                 + +++p++aq+s W+s+ipk+lr     ++++ k ++kewnpatf++vi +LiGSqai+m+ l+++f++ytrkadaki+lLrevi+kv++GE+vdve+l
  EEA21404.1  45 TGEAVPKIAQASTWQSIIPKFLRGG--GSNTSPKIRSKEWNPATFYVVIWTLIGSQAIQMLVLRKDFENYTRKADAKIRLLREVIQKVNNGETVDVERL 141
                 6789********************9..78888999**************************************************************** PP

     DUF5321 103 LGtGdeekEreWeevLkeieeedallqkkkkkkekeeekkeeeeekkeea 152
                 LGtGde kEreWeevL+eie+ed+++++k+++++++   ++++e++k ++
  EEA21404.1 142 LGTGDEVKEREWEEVLQEIEDEDSVWRQKSHDQRSSDGGSSSDEKDKPRD 191
                 *****************************999988877666666555443 PP

>> MRI  Modulator of retrovirus infection
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   2.5   1.5e-05      0.13       6      80 ..     131     206 ..     127     215 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.5e-05
         MRI   6 nEaElVDvALgiLiEarkqekpleqlalagadkpelspacsespssss.gsrseeedsgkdapapglspsqgpags 80 
                 n  E VDv   +   +  +e+ +e++ +   d++    + s+   ss+ gs+s+e+d+  da  ++ + +q   ++
  EEA21404.1 131 NNGETVDVERLLGTGDEVKEREWEEVLQEIEDEDSVWRQKSHDQRSSDgGSSSDEKDKPRDAVVKSEKATQPSDVP 206
                 7788888876555667778999***********99999989988888868999999*****999876665544443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (217 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       810  (0.0451782); expected 358.6 (0.02)
Passed bias filter:                      458  (0.0255452); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.28s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 1493.46
//
Query:       EEA21405.1  [L=480]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.9e-06   25.9  11.3    1.6e-05   24.9  11.3    1.5  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.9  11.3   8.8e-10   1.6e-05       1      37 [.       9      45 ..       9      47 .. 0.90

  Alignments for each domain:
  == domain 1  score: 24.9 bits;  conditional E-value: 8.8e-10
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfysess 37
                ++C nCr++ +KCd+k   Cs+C + n  C  y+++s
  EEA21405.1  9 KSCRNCRRRDIKCDRKLNGCSQCSRANISCPGYPNPS 45
                59*************6666***********9998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (480 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       525  (0.0292822); expected 358.6 (0.02)
Passed bias filter:                      341  (0.0190195); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.31s 00:00:00.89 Elapsed: 00:00:00.51
# Mc/sec: 2825.24
//
Query:       EEA21406.1  [L=331]
Description: aldo/keto reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      8e-53  179.5   0.0    9.8e-53  179.2   0.0    1.0  1  Aldo_ket_red  Aldo/keto reductase family
  ------ inclusion threshold ------
        0.1   12.9   0.0        4.3    7.7   0.0    2.4  2  DIMCO_N       Dinitrogenase iron-molybdenum cofactor, N-termi


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  179.2   0.0   1.1e-56   9.8e-53       3     293 ..      13     311 ..      13     312 .. 0.95

  Alignments for each domain:
  == domain 1  score: 179.2 bits;  conditional E-value: 1.1e-56
                   EEE-SSS-ST..TS-HHHHHHHHHHHHHTT--EEE--TT-..TTTHHHHHHHHHHHH-TTTGGG-EEEEEE.--SSSTTSSSS-HHHHHHHHHHHHH CS
  Aldo_ket_red   3 glGtwqlgsk.eeiskeealellrraleaGinffDtAevY..gkgqseellGealkksrkkreeviiatKv.dlrdaeiksglskeniresleeslk 95 
                   glG+ +++++    s+ee +++l++a+ aG+n ++ A++Y   ++ s +l+ ++++ ++++ ++v++++K   ++  +   + s+e +r+sl++ lk
    EEA21406.1  13 GLGLSRFTQPgFSLSDEETFKVLKAAINAGVNVWNGADFYgtPDNNSLHLMNRYFSTYPEDADKVVLCIKSgIKDMRTFALDCSPEALRASLDNALK 109
                   78999999998899**************************777888999999******************9434445567789************** PP

                   HHT-.S-EEEEEE-S--TTS-.HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHHHHTTT--EEEEE-B-BTT.-HHHHTTHHHHHHHTT-EEEEBS CS
  Aldo_ket_red  96 rLgt.dyvDllllHrpdpslpsieevldaleelvkeGkiraiGvSnfsveqlekakkkkkvkivavqveynll.releeegllelckkkgvpliays 190
                    L+  +++D++ ++r dp++p +ee +++l+e++ eGki +i +S++ ve +++a   +  +i +v++e +l+ ++++e+g++  c ++g+ l+a++
    EEA21406.1 110 ILDGkKKIDIFGCARTDPAVP-VEESIKVLAEMKAEGKIGGIQLSEVRVETIRRA--AAIAQIDMVEAEISLWaTDVFENGVAAICGELGIVLVAHT 203
                   ****99***************.*******************************99..**************************************** PP

                   TTGGGTTGTTTSS---SSSCCC-------..TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTS.....TT-SEEEE--SSHHHHHHHHGGGG-- CS
  Aldo_ket_red 191 plggGlltgkyqseedkedkeprkdlkrd..ertsknldaaeelselakehgvslaqlalryalsq.....pavgivipgasnieqlednldalelk 280
                   plg G+ltg+ +s +d+++ + ++++ r   e+++knl+++eel+ +ak +g++ +qlal+++  q      +v +++ g+++++++ +n +    +
    EEA21406.1 204 PLGAGMLTGQLKSLDDVPKNDYHRHFPRWqpENFDKNLLLVEELKIFAKAKGCTTSQLALNWIKIQsrkpgMPVLVPVAGSRSVQRISENTKDI--D 298
                   ******************999999998889*********************************999888888**********************..* PP

                   --HHHHHHHHHHH CS
  Aldo_ket_red 281 lseeevaeldell 293
                   l+++++a+l ++l
    EEA21406.1 299 LTDDDIAKLSSIL 311
                   *********9986 PP

>> DIMCO_N  Dinitrogenase iron-molybdenum cofactor, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0     0.021   1.8e+02      63      84 ..      95     116 ..      80     119 .. 0.71
   2 ?    7.7   0.0   0.00048       4.3      13      82 ..     123     194 ..     121     196 .. 0.79

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.021
     DIMCO_N  63 ldigveseaLkeAvrlLkGege 84 
                 ++ ++ +++L +A+++L G+++
  EEA21406.1  95 CSPEALRASLDNALKILDGKKK 116
                 344445799**********875 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.00048
     DIMCO_N  13 araLpgvdvaqLlevLqe.rlgeplteekLakltvtdLktala..sadgeeeeldigveseaLkeAvrlLkGe 82 
                 ar+ p v v++ ++vL+e + + ++   +L++++v+ ++ a a  + d+ e+e++   +   +++ v+++ Ge
  EEA21406.1 123 ARTDPAVPVEESIKVLAEmKAEGKIGGIQLSEVRVETIRRAAAiaQIDMVEAEIS-LWATDVFENGVAAICGE 194
                 67778999999999998835789****************9888779998888877.45566666666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (331 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       501  (0.0279436); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2279.89
//
Query:       EEA21407.1  [L=401]
Description: hypothetical protein PMAA_052160 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
      0.031   14.4   3.1       0.29   11.3   1.0    2.6  2  Zn-ribbon_8    Zinc ribbon domain
       0.09   12.8   0.9        2.2    8.4   0.5    2.3  2  DZR            Double zinc ribbon
        3.4    7.9   4.9        3.6    7.8   0.6    2.8  3  Auto_anti-p27  Sjogren's syndrome/scleroderma autoantigen 1 (


Domain annotation for each model (and alignments):
>> Zn-ribbon_8  Zinc ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.0     0.039   2.4e+02      21      37 ..      34      48 ..      24      50 .. 0.69
   2 ?   11.3   1.0   4.8e-05      0.29       6      36 ..     345     374 ..     344     375 .. 0.73

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.039
  Zn-ribbon_8 21 isdapltaCPeCgsevr 37
                 isd   ++C +C +++r
   EEA21407.1 34 ISD--IKTCASCRGPLR 48
                 443..566****99887 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 4.8e-05
  Zn-ribbon_8   6 YrCeeCghefe....vlqsisdapltaCPeCgsev 36 
                  Y C++ gh f+        ++   + +CPeCg++v
   EEA21407.1 345 YYCRN-GHPFTigecG---MA-MQQSVCPECGEPV 374
                  99***.*****65331...33.33778*****875 PP

>> DZR  Double zinc ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.0     0.037   2.2e+02      12      24 ..      37      49 ..      29      64 .. 0.78
   2 ?    8.4   0.5   0.00036       2.2      17      38 ..     357     374 ..     354     380 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.037
         DZR 12 arfCseCgtklka 24
                 ++C  C+ +l+ 
  EEA21407.1 37 IKTCASCRGPLRD 49
                5677777777764 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.00036
         DZR  17 eCgtklkavaaedrCpsCgekv 38 
                 eCg +++    + +Cp+Cge+v
  EEA21407.1 357 ECGMAMQ----QSVCPECGEPV 374
                 7999998....79999999986 PP

>> Auto_anti-p27  Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.1      0.14   8.3e+02      16      25 ..      38      47 ..      38      49 .. 0.85
   2 ?   -2.1   0.0      0.74   4.4e+03       4      12 ..     309     317 ..     309     320 .. 0.87
   3 ?    7.8   0.6   0.00061       3.6      10      24 ..     359     373 ..     357     380 .. 0.90

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.14
  Auto_anti-p27 16 etCpvCgvPL 25
                   +tC  C  PL
     EEA21407.1 38 KTCASCRGPL 47
                   5899999998 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.74
  Auto_anti-p27   4 gelLlkGwt 12 
                    +e+Ll+G t
     EEA21407.1 309 AEKLLRGTT 317
                    799****87 PP

  == domain 3  score: 7.8 bits;  conditional E-value: 0.00061
  Auto_anti-p27  10 GwtMLaetCpvCgvP 24 
                    G +M +++Cp+Cg P
     EEA21407.1 359 GMAMQQSVCPECGEP 373
                    99**********977 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (401 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       680  (0.0379274); expected 358.6 (0.02)
Passed bias filter:                      597  (0.033298); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 2686.49
//
Query:       EEA21408.1  [L=1391]
Description: NF-X1 finger and helicase domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.4e-40  139.0   0.0    4.2e-40  137.5   0.0    1.8  2  AAA_12           AAA domain
    4.2e-27   95.6   0.1    1.9e-26   93.4   0.0    2.1  2  AAA_11           AAA domain
    4.1e-10   40.2   0.0    1.5e-09   38.4   0.0    2.0  1  AAA_19           AAA domain
    3.5e-07   30.1   0.1    0.00031   20.5   0.0    2.3  2  AAA_30           AAA domain
    3.6e-05   23.2   0.6      0.063   12.5   0.1    2.4  2  DUF2075          Uncharacterized conserved protein (DUF2075)
     0.0023   17.8   5.5      0.005   16.7   5.5    1.6  1  zf-CCCH          Zinc finger C-x8-C-x5-C-x3-H type (and simil
      0.007   16.6   0.0      0.027   14.7   0.0    2.0  1  Cyclase_polyket  Polyketide synthesis cyclase
     0.0084   15.0   0.0      0.014   14.2   0.0    1.3  1  Adeno_IVa2       Adenovirus IVa2 protein
  ------ inclusion threshold ------
      0.016   15.2   0.1      0.041   13.9   0.1    1.6  1  ResIII           Type III restriction enzyme, res subunit
      0.019   14.7   0.2        1.1    8.9   0.0    3.1  3  Viral_helicase1  Viral (Superfamily 1) RNA helicase
      0.042   12.9   0.0      0.087   11.9   0.0    1.4  1  T2SSE            Type II/IV secretion system protein


Domain annotation for each model (and alignments):
>> AAA_12  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0         3   4.8e+03      72      98 ..     438     479 ..     410     486 .. 0.66
   2 !  137.5   0.0   2.6e-43   4.2e-40       1     198 [.     930    1158 ..     930    1159 .. 0.87

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 3
      AAA_12  72 v...............ekseeekekkeksyiNeeEaelvvkl 98 
                 v               ++++++k++++  + N++Ea++ +kl
  EEA21408.1 438 VinsqaqaparkrqgqDGNKTQKKDSDGLWKNPQEATVFLKL 479
                 444455555555544444444444555888899999888776 PP

  == domain 2  score: 137.5 bits;  conditional E-value: 2.6e-43
      AAA_12    1 lerSlferllkke.....kekvvlLdtqYRmhpeIsrfpsklfYkgkLkdaesvkkreleaqealeepleplvfidvekseeekekke...ksyiNe 89  
                  l+ S+ferl++ +       ++++L+tq Rmhp+I++++++++Y+ +L+da+sv+++++      e   ++l+++d  + e + ++ e   +s  N+
  EEA21408.1  930 LDVSMFERLVETGsamgcGLPYSTLQTQRRMHPSIAQLVRETLYS-HLQDAPSVSEYPSV-----EGIRKRLFWLDHREPEGNPSNAEaaaTSRWND 1020
                  589**********99999999***********************8.79********9998.....78888899999965554444444556****** PP

      AAA_12   90 eEaelvvklvekllkkgseeerkkigvitpYraqvellkkklke.......keeekseke..............................ievntvd 149 
                   E+++ + lv++l+ +g+ +   +i+v+tpY  q++ l+++l++       +       +                              ++v+t+d
  EEA21408.1 1021 YEVTMTTALVNHLVCQGEYA-SGEIAVLTPYLGQLQKLRRRLSRsfaitlgD-------RdqddldkaglqedeeqaptptavkgtllqnLRVATID 1109
                  ******************99.8*********************955555550.......3444555556666666677788888999999******* PP

      AAA_12  150 gfQGrekdviilslVRsnekkeigflkderrlNValTRAkskliivGnk 198 
                  +fQG+e +v+++slVRsn++++ gfl+ ++r+NV l+RAk+ ++i+Gn+
  EEA21408.1 1110 NFQGEEASVVVISLVRSNPQNKCGFLRTSNRINVLLSRAKNGMYIIGNS 1158
                  ***********************************************96 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0       1.2     2e+03     171     208 ..     401     443 ..     364     449 .. 0.73
   2 !   93.4   0.0   1.2e-29   1.9e-26       2     258 ..     593     912 ..     592     914 .. 0.78

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 1.2
      AAA_11 171 kkerkelskeleeaeesle.....eevldeaeivltTlsgags 208
                  k  ++ ++e  +  ++l+       ++++  +v++T+  +++
  EEA21408.1 401 DKMTTTQREEWWNMSKRLQsgalvCLIMQRNFVVFCTVINSQA 443
                 44444444444444444444444488999999*****988765 PP

  == domain 2  score: 93.4 bits;  conditional E-value: 1.2e-29
      AAA_11   2 lndsqreaiksalseseitliqGPPGtgKTktivellsqllsrrkseeeksakpriLvCapSNaAvDellerllrglldsegekykpkivRvgneeeri 100
                 l+d q+ a+ ++l+++   liqGPPGtgK+ t v+l+++ll +  + + +++   i   + +N A D+lle ll+       ++ + +ivR+g +++  
  EEA21408.1 593 LDDAQASALVETLQRKI-GLIQGPPGTGKSYTGVALIKVLLAN--KGNGRKKLGPIICVTYTNHALDQLLESLLE-------KNVTKQIVRMGGQSK-- 679
                 8999**********996.**********************665..4577777778888899**************.......888899********5.. PP

      AAA_11 101 seavksvsleekvekrlekee............................kaqlakeiskeleklakelrafeeeeek...................... 149
                 se++k++ l+e  ++  + ++                            +                                                 
  EEA21408.1 680 SESLKPYNLRELAKRFDKTKMekgslwtlhnsletsekdfsqigfregiS--------------------------Parvmihlrdsfpthynqlfgie 752
                 99999999888777665554444554444444444444444444444440..........................14556666666666666666666 PP

      AAA_11 150 ...................................................eklkkskekskskleqerrklkkerkelskeleeaeesleeevldeae 197
                                                                       ++ +++ +++++qe+  +  + ++ + e++++++++   +l++a+
  EEA21408.1 753 kdgfqnahsdnpgkvfdrwrrsggkaskdqirnvgqlesislvqmsqpereSLYAYWQSQIQDDMQQELIGICLSHSRTKYEFDNIRSEVDLRCLSQAD 851
                 6666666666666666666666666666666677777777777777777657788889999************************************** PP

      AAA_11 198 ivltTlsgagskl..leklakkfdvviIDEAaqavEpstliPlrlgakkvvLvGDpkQLpatv 258
                 ++  T sg +++l  l++l  + +vv+  EA+  +E   l +l+  +++++L+GD+ QL++ v
  EEA21408.1 852 VIGVTTSGLARNLdmLRRL--QSKVVLCEEAGEVLESHLLTALLPSVEHAILIGDHYQLRPQV 912
                 ********96643224444..9***************************************87 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.4   0.0     9e-13   1.5e-09       2     142 ..     598     909 ..     597     913 .. 0.81

  Alignments for each domain:
  == domain 1  score: 38.4 bits;  conditional E-value: 9e-13
      AAA_19   2 reave.alkekvllvtaGpGtGKTrvlkhivallvelggv...kpeeillvaftgrAakelrerlaalgae.........................atT 71 
                  +a+  +l++k+ l+ ++pGtGK+++ ++ +++l++++g    k+ +i++v++t++A ++l e+l +  ++                         a  
  EEA21408.1 598 ASALVeTLQRKIGLIQGPPGTGKSYTGVALIKVLLANKGNgrkKLGPIICVTYTNHALDQLLESLLE--KNvtkqivrmggqskseslkpynlrelA-- 692
                 56664499**************************9987651115699******************33..3343556666666666666655555551.. PP

      AAA_19  72 iHrlal............................................................................................. 77 
                                                                                                                    
  EEA21408.1 693 -----Krfdktkmekgslwtlhnsletsekdfsqigfregisparvmihlrdsfpthynqlfgiekdgfqnahsdnpgkvfdrwrrsggkaskdqirnv 786
                 .....0555555566666666666679************************************************************************ PP

      AAA_19  78 ....................................................................ldfddlltealelle......eaeeekklqe 102
                                                                                     +                    + +  + l +
  EEA21408.1 787 gqlesislvqmsqpereslyaywqsqiqddmqqeligiclshsrtkyefdnirsevdlrclsqadvigV-------------TtsglarNLDMLRRL-Q 871
                 **********************************************99999998877777644333322.............022222355555667.7 PP

      AAA_19 103 eellivDEfqdvdelqyrLlkallgekkklllvGDpdQli 142
                  ++++  E+ +v  l+ +Ll all++ ++ +l+GD+ Ql 
  EEA21408.1 872 SKVVLCEEAGEV--LESHLLTALLPSVEHAILIGDHYQLR 909
                 77999***9998..7789******88899********986 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5   0.0   1.9e-07   0.00031       2      66 ..     593     662 ..     592     706 .. 0.83
   2 !    7.2   0.0    0.0022       3.7      66     130 ..     853     910 ..     836     919 .. 0.81

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 1.9e-07
      AAA_30   2 lnaeQaaavealltsgdrvavltGpAGtGKttalkalreaweaa.g......grviglAptgkaAkvLaeel 66 
                 l++ Qa+a+ ++l+ +  + +++Gp+GtGK+++  al +++ a+ g      g++i ++ t+ a ++L e+l
  EEA21408.1 593 LDDAQASALVETLQRK--IGLIQGPPGTGKSYTGVALIKVLLANkGngrkklGPIICVTYTNHALDQLLESL 662
                 7899*****9999888..9**************999977777764699*****************9998875 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0022
      AAA_30  66 lgieastiakllkrlkgrarlepgtllivDEagmv.dtkqlaallkaaekagakvilvGDerQlas 130
                 +g+++s +a+ l+ l++     ++++++  Eag v  ++ l+all ++e+     il+GD+ Ql +
  EEA21408.1 853 IGVTTSGLARNLDMLRR----LQSKVVLCEEAGEVlESHLLTALLPSVEH----AILIGDHYQLRP 910
                 45666666666655553....4569********9879999********99....9********975 PP

>> DUF2075  Uncharacterized conserved protein (DUF2075)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.5   0.1   3.9e-05     0.063       2      59 ..     608     671 ..     607     703 .. 0.72
   2 !    8.7   0.0   0.00054      0.89     343     360 ..    1138    1155 ..    1114    1157 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 3.9e-05
     DUF2075   2 avvlVtGvaGtGKtvvllnllael......eddeeertavylsvNhplvlvlrealakkeekkk 59 
                 ++ l++G +GtGK++ +++l+  l       +++++    + + Nh+l + l++ l+k+ +k+ 
  EEA21408.1 608 KIGLIQGPPGTGKSYTGVALIKVLlankgnGRKKLGPIICVTYTNHALDQLLESLLEKNVTKQI 671
                 6779****************99997666554555566666788999999999888888774443 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.00054
     DUF2075  343 kNayrVLLtRGrkGlyiy 360 
                   N+++VLL+R+ +G+yi 
  EEA21408.1 1138 SNRINVLLSRAKNGMYII 1155
                  7***************95 PP

>> zf-CCCH  Zinc finger C-x8-C-x5-C-x3-H type (and similar)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   5.5   3.1e-06     0.005       4      25 ..       5      25 ..       3      27 .. 0.93

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 3.1e-06
                HCBCHHHHHS--TTGGG-SSBS CS
     zf-CCCH  4 elCrffmrtGyCkyGdrCkFaH 25
                + C+ f r+G+Cky  +CkF H
  EEA21408.1  5 RTCHEFERNGTCKY-KNCKFQH 25
                67************.******* PP

>> Cyclase_polyket  Polyketide synthesis cyclase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   1.6e-05     0.027      59      91 ..     292     324 ..     260     327 .. 0.92

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.6e-05
  Cyclase_polyket  59 ealaearekpefkkvserlseyvspydpetWrs 91 
                      + ++++r  p+f+++s+r sey+ pydp++W++
       EEA21408.1 292 KDIRRIRIMPTFQEISSRRSEYLPPYDPTQWHE 324
                      67899999***********************86 PP

>> Adeno_IVa2  Adenovirus IVa2 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.0   8.9e-06     0.014      57     108 ..     577     628 ..     558     636 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 8.9e-06
  Adeno_IVa2  57 eneevkdiekldakllrddGelsslnyglqPviGviyGPtGsGksqllrnli 108
                    +  d++kl ++   dd + s+l   lq  iG+i GP G+Gks    +li
  EEA21408.1 577 RVGHTTDLQKLRQNSSLDDAQASALVETLQRKIGLIQGPPGTGKSYTGVALI 628
                 5567889999999999999**************************7444444 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.1   2.5e-05     0.041       7      74 ..     596     662 ..     586     722 .. 0.74

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 2.5e-05
                 HHHHHHHHHT......TTSEEEEEESTTSTHHHHHHHHHHHH-S..........-EEEEESSHHHHHHHHHHG CS
      ResIII   7 yQeeaienlleklkskrdkrglikmaTGtGKTlvaaklierllkkgkee.....kflflvprkslleqtleef 74 
                  Q++a+ ++l      ++k gli+ + GtGK+++ ++li+ ll ++++       ++ +  +++ l+q+le +
  EEA21408.1 596 AQASALVETL------QRKIGLIQGPPGTGKSYTGVALIKVLLANKGNGrkklgPIICVTYTNHALDQLLESL 662
                 5555555554......6899********************999887766788999999999999999999776 PP

>> Viral_helicase1  Viral (Superfamily 1) RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.1      0.81   1.3e+03       2      14 ..     611     623 ..     610     635 .. 0.79
   2 ?    1.7   0.0      0.11   1.8e+02      80     107 ..     888     915 ..     866     931 .. 0.76
   3 ?    8.9   0.0    0.0007       1.1     184     233 ..    1104    1155 ..    1051    1156 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.81
  Viral_helicase1   2 vvhGvpGcGKStl 14 
                      +++G pG GKS  
       EEA21408.1 611 LIQGPPGTGKSYT 623
                      799********86 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.11
  Viral_helicase1  80 lllaalskaklvilfGDplQipfhsrna 107
                      ll a l++++ +il+GD++Q   + +n 
       EEA21408.1 888 LLTALLPSVEHAILIGDHYQLRPQVQNY 915
                      345678999***********88775554 PP

  == domain 3  score: 8.9 bits;  conditional E-value: 0.0007
  Viral_helicase1  184 evttvhevqGltfdkVt..lvllketdlelisesrenllvAlTRhrkslvil 233 
                        v t    qG+++++V+  lv++++ +++ + ++++   v l+R++++++i+
       EEA21408.1 1104 RVATIDNFQGEEASVVVisLVRSNPQNKCGFLRTSNRINVLLSRAKNGMYII 1155
                       47899*********99622688888888988899**************9997 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   5.3e-05     0.087      96     154 ..     577     632 ..     549     638 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 5.3e-05
       T2SSE  96 RkksakeltlddlgaeealkekiaevlrkavrerglilvsGgTgsGKttllyallkein 154
                 R    +  +l++l+++ +l++++a++l +   +r++ l+ G+ g+GK+ +  al+k + 
  EEA21408.1 577 R--VGHTTDLQKLRQNSSLDDAQASALVET-LQRKIGLIQGPPGTGKSYTGVALIKVLL 632
                 4..3455679*****************999.6788999**********99999988775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1391 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       592  (0.0330191); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        64  (0.00356964); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.90u 0.35s 00:00:01.25 Elapsed: 00:00:00.52
# Mc/sec: 8034.51
//
Query:       EEA21409.1  [L=475]
Description: dimethylaniline monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.6e-39  133.5   0.0    2.5e-22   79.0   0.0    3.0  3  FMO-like        Flavin-binding monooxygenase-like
    8.7e-17   61.3   0.0    6.6e-11   42.0   0.0    3.1  3  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
    8.5e-13   48.6   0.0    0.00018   21.2   0.0    3.1  3  DAO             FAD dependent oxidoreductase
      2e-12   47.0   0.0    7.7e-12   45.0   0.0    1.9  1  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    3.1e-09   36.9   0.0    1.8e-08   34.5   0.0    2.3  2  NAD_binding_8   NAD(P)-binding Rossmann-like domain
    4.7e-09   36.4   0.1    2.2e-08   34.3   0.1    2.2  2  NAD_binding_9   FAD-NAD(P)-binding
      3e-08   33.2   0.1      3e-06   26.6   0.0    2.7  3  K_oxygenase     L-lysine 6-monooxygenase (NADPH-requiring)
    3.8e-07   29.6   0.0    0.00011   21.5   0.0    2.2  2  Thi4            Thi4 family
    0.00064   18.6   0.0     0.0043   15.9   0.0    2.1  2  MCRA            MCRA family
    0.00074   18.7   0.1      0.037   13.1   0.2    2.2  2  FAD_binding_2   FAD binding domain
     0.0011   17.7   0.0     0.0099   14.6   0.0    2.2  3  HI0933_like     HI0933-like protein
     0.0043   17.6   0.0        1.3    9.7   0.0    2.9  3  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
      0.029   13.7   0.0        3.3    6.9   0.0    2.2  2  Amino_oxidase   Flavin containing amine oxidoreductase
       0.12   11.9   0.0       0.22   11.0   0.0    1.4  1  Glu_dehyd_C     Glucose dehydrogenase C-terminus
       0.13   12.7   0.0        0.8   10.2   0.0    2.3  2  Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domai


Domain annotation for each model (and alignments):
>> FMO-like  Flavin-binding monooxygenase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.2   0.0   0.00015      0.18       3      52 ..      16      67 ..      14      74 .. 0.78
   2 !   79.0   0.0   2.1e-25   2.5e-22      45     217 ..      86     261 ..      81     270 .. 0.84
   3 !   40.9   0.0   7.3e-14   8.8e-11     298     440 ..     274     419 ..     263     429 .. 0.73

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00015
    FMO-like  3 kvaviGaGvsGlasikc.cleeglep.tcfersddiGGlwrfkenveeGras 52
                ++a+iGaG +Gla+      ee++     fe+ +  GG w+++ + +  + +
  EEA21409.1 16 RIAIIGAGAAGLAAATYlSSEEQFSHiEVFEQRNSPGGTWNYSSEKRAPKVT 67
                8***********98765145666655169*************9887766555 PP

  == domain 2  score: 79.0 bits;  conditional E-value: 2.1e-25
    FMO-like  45 nveeGras.iyksvvsnsskemscfsdfplpedypnflhnsklleylklfakefdllkyiqfkttvcsvkkrpdfstsGqwevvtek..egkkesavfd 140
                 ++++G  s +y+ + +n    ++ fs  p+p   p f  ++ + eyl+++a        i ++t+v +++k +       we+ t++     +  +++d
  EEA21409.1  86 SADDGFVSpLYRDLDTNIPHSLMNFSTQPFPAGSPLFPSRDVVTEYLHQYAASL--KHLIHYNTQVKNLTKIN-LDGNECWELETQNlkTHETSISIYD 181
                 5677765549*****************************************864..45599*********985.44556799988861144555689** PP

    FMO-like 141 avmvctGhhvnphlplesfpGiekfkGqy....fhsrdykepevfkgkrvlviGlGnsggdiavelsrtaeq.vllstrsGs 217
                 av+v  Gh+   ++p     Gi++f  qy     hs+ y epe fk+k+v+v+G+  sg d++v++++  ++ vl+s r+ s
  EEA21409.1 182 AVVVANGHYSDIFIPD--IKGIKEFHEQYpgviSHSKYYGEPEDFKDKKVIVVGFSASGLDVSVQIAQLCQHpVLVSERQPS 261
                 **********999995..6788887755433228**********************************98764888888755 PP

  == domain 3  score: 40.9 bits;  conditional E-value: 7.3e-14
    FMO-like 298 vkssvkel..tetsaifedgtveedidvvifatGytfafpfle...eslvkveknkvslykkvfpanlekptlaiiGliqplGsilptvelqarwavrv 391
                 + ++++e+   + ++ f +g +e +id vif+tGy ++fpfl    +sl    ++   ly+++f   +++ptla + l + +   +p++e q+ +++rv
  EEA21409.1 274 MMPTIEEFliGKRAVRFSNGHIETGIDSVIFCTGYHYSFPFLGplrQSLNPDGSHVRHLYQHLFY--IDNPTLAFVALPKRV-VPFPISEAQSAYIARV 369
                 5666666522366888*************************852226666666677789999995..79********98766.569************* PP

    FMO-like 392 lkGlkklpsekelle...eitekkekkakrfgesksktiqtdyiayldelaa 440
                      +lp++  + e   ++++  ++  + +  + +   +++yi+ l ++ +
  EEA21409.1 370 WANRVQLPTKAGMHEweaDLIASCQELSRIHE-M-KYPKDANYINELYDICK 419
                 *********99886521133333333322222.2.22345678887777765 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.3   0.0   0.00025       0.3       2      29 ..      19      47 ..      18      71 .. 0.76
   2 !   42.0   0.0   5.5e-14   6.6e-11      66     218 ..     111     282 ..      87     287 .. 0.74
   3 !    5.6   0.0    0.0068       8.2     246     277 ..     287     318 ..     282     333 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00025
  Pyr_redox_3  2 IiGaGPaGlaaaielkka.gledylilEk 29
                 IiGaG+aGlaaa+ l    +++++ + E+
   EEA21409.1 19 IIGAGAAGLAAATYLSSEeQFSHIEVFEQ 47
                 9***********99875414455556665 PP

  == domain 2  score: 42.0 bits;  conditional E-value: 5.5e-14
  Pyr_redox_3  66 etspafslkeeklsrkealeYlrevaksfelpiklfeeVesvkk....edegfevetske.tyeA.....kkviiAtGefdkPnklnipGeek.lvk. 151
                  +t+p  + +   +sr+ + eYl ++a+s +  i+++++V++++k     +e  e+et++  t e+     + v++A G ++    ++i+G ++ + + 
   EEA21409.1 111 STQPFPAGSPLFPSRDVVTEYLHQYAASLKHLIHYNTQVKNLTKinldGNECWELETQNLkTHETsisiyDAVVVANGHYSDIFIPDIKGIKEfH-Eq 207
                  4556444455589****************************99974322455888888742333322223579*********9999999998631.21 PP

  Pyr_redox_3 152 ......hyskvkefhkyagqkvvViGgknSavDaAlelvrk.gaeVtvvtrgseiek.eesdpsyslkpdienrl 218
                        h++++ e+++++++kv+V+G + S+ D+ +++++   + V v  r+ ++ + +e++ + ++ p+ie+ l
   EEA21409.1 208 ypgvisHSKYYGEPEDFKDKKVIVVGFSASGLDVSVQIAQLcQHPVLVSERQPSLLDpSETSTNLRMMPTIEEFL 282
                  233344999999****************************95677888888776655255777778888888766 PP

  == domain 3  score: 5.6 bits;  conditional E-value: 0.0068
  Pyr_redox_3 246 kvktedgkkvevkddvvlatGykpdlsflkks 277
                   v++++g+  +  d v+++tGy+ ++ fl   
   EEA21409.1 287 AVRFSNGHIETGIDSVIFCTGYHYSFPFLGPL 318
                  57889998888899************999764 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.0   1.5e-07   0.00018       2      41 ..      17      59 ..      16      80 .. 0.85
   2 !   19.7   0.0   4.4e-07   0.00052     149     218 ..     129     199 ..     122     239 .. 0.70
   3 ?    4.1   0.0     0.023        28     188     264 ..     293     375 ..     270     419 .. 0.64

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 1.5e-07
                EEEECTSHHHHHHHHHHHHTT....EEEEESSSSTTSSGGGSSE CS
         DAO  2 vviiGGGiiGlstAyeLarrg....VtllekgdiagsgaSgrns 41
                ++iiG+G +Gl++A +L+ +     + ++e+++ +g g+   +s
  EEA21409.1 17 IAIIGAGAAGLAAATYLSSEEqfshIEVFEQRNSPG-GTWNYSS 59
                9****************85534779**********9.8866555 PP

  == domain 2  score: 19.7 bits;  conditional E-value: 4.4e-07
                 HHHHHHHHHHTT-EEEESECEEEEEEEE...TCEEEEE...EECT.EEE.EEEEEEEE--GGGHH.HHHTTCTTTSEEE CS
         DAO 149 taalaraaealGveilegtevtgleeed...gkvwgve...rttp.gen.daadavVnaaGawsd.llgllkeldlpis 218
                 t +l + a++l   i+++t+v++l + +   +  w++e     +  ++  +++davV+a+G++sd ++   +++    +
  EEA21409.1 129 TEYLHQYAASLKHLIHYNTQVKNLTKINldgNECWELEtqnL-KThETSiSIYDAVVVANGHYSDiFI---PDI----K 199
                 55666668888999**********664444588899988852.3323334589************766...444....2 PP

  == domain 3  score: 4.1 bits;  conditional E-value: 0.023
                 EEE.EEEEEEEE--GGGHH..HHHTT.CTT..T.SEEEEEEEEEEEEEECCTHSTGSGCSEEEEEEEETTTTEEEEEETTSEEE CS
         DAO 188 gen.daadavVnaaGawsd..llgll.kel..d.lpispvrgqvlvlkplseklvspaailpvpetdddgrgvyvtprkdgrvl 264
                 g++ + +d v+ ++G + +  +lg l + l  d   ++ +  + + ++++++++v+  +   vp+++ ++ + y+ + + +rv 
  EEA21409.1 293 GHIeTGIDSVIFCTGYHYSfpFLGPLrQSLnpDgSHVRHLYQHLFYIDNPTLAFVAL-PKRVVPFPISEAQSAYIARVWANRVQ 375
                 444355799******998876554444444332355566666777776666655444.33333335555555555554346555 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.0   0.0   6.4e-15   7.7e-12       2     179 ..      16     266 ..      15     309 .. 0.76

  Alignments for each domain:
  == domain 1  score: 45.0 bits;  conditional E-value: 6.4e-15
                  SEEEE--SHHHHHHHHHHHH..HTS-EEEEETTHCHHHCSHHHHC..HHHHHHHHHHHHH...................................... CS
                  xxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxx...................................... RF
  Pyr_redox_2   2 dvvviGgGpAGlaaaltlaq..agakvtlvelegtclnggcllsk..allgvaedaeias...................................... 57 
                  ++++iG+G+AGlaaa++l+   +   + ++ ++++ ++g+  +s+   + +v  ++   +                                      
   EEA21409.1  16 RIAIIGAGAAGLAAATYLSSeeQFSHIEVF-EQRNSPGGTWNYSSekRAPKVTVPKT--Tpddnnetpyepassaddgfvsplyrdldtniphslmnf 110
                  79******************7545567777.55556655555433112222222222..13455566788888************************* PP

                  .............................HHHHCHHHHCCCCHCCTCEEEE.ESCEEEEETEEECTCEEEEEESEEEE---..EEE-BCTCTTC.TTB CS
                  .............................xxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxx RF
  Pyr_redox_2  58 .............................evvkklnqgielllgeevvkid.pgkkkvklekkkegdeekiaydklvlAtG..ssprdlgipGvaenv 123
                                               +++  +n+++++l++   +++d +++ +++ +++k+ ++    yd++v+A G  s  ++++i+G +e  
   EEA21409.1 111 stqpfpagsplfpsrdvvteylhqyaaslKHLIHYNTQVKNLTK---INLDgNECWELETQNLKTHETSISIYDAVVVANGhySDIFIPDIKGIKEFH 205
                  *******************9999999999888889999998888...88874444677777777677767778********55566666*****5544 PP

                  EEC.CSECHHHHHHCCSS-T.SEEEEES-SHHHHHHHHHHHHHT-E.EEEEESSSSSS..T CS
                  xxx.xxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxx..x RF
  Pyr_redox_2 124 gkl.vrtldsaealklkllp.krivvvGgGyiGvElAaalaklgke.vtlveardrll..r 179
                   +    +++s+ + + +  + k+++vvG ++ G++++ ++a+l ++ v + e+ + ll  +
   EEA21409.1 206 EQYpGVISHSKYYGEPEDFKdKKVIVVGFSASGLDVSVQIAQLCQHpVLVSERQPSLLdpS 266
                  3330234555555555555489*********************88889999**99999532 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.5   0.0   1.5e-11   1.8e-08       1      36 [.      19      56 ..      19      72 .. 0.85
   2 ?   -1.9   0.0       3.4     4e+03      41      64 ..     129     152 ..     123     154 .. 0.80

  Alignments for each domain:
  == domain 1  score: 34.5 bits;  conditional E-value: 1.5e-11
                   EE--SHHHHHHHHHHHCC.TE.EEEEE-SSSSSSGGG- CS
  NAD_binding_8  1 IvGaGlsGlvaAylLaka.gf.dvlllekrdrlGGraa 36
                   I+GaG++Gl+aA +L+ + +f +++++e+r+++GG + 
     EEA21409.1 19 IIGAGAAGLAAATYLSSEeQFsHIEVFEQRNSPGGTWN 56
                   9**************98768878************876 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 3.4
                    TTCEECTS---EEETTHHHHCHHH CS
  NAD_binding_8  41 pgvrvdygahifhgsgyypnvrrl 64 
                     ++ ++y a+  h ++y+++v++l
     EEA21409.1 129 TEYLHQYAASLKHLIHYNTQVKNL 152
                    678999999999999999999876 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.3   0.1   1.8e-11   2.2e-08       1     155 [.      18     189 ..      18     190 .. 0.74
   2 ?   -1.9   0.0       2.5     3e+03     135     155 ..     287     308 ..     284     309 .. 0.73

  Alignments for each domain:
  == domain 1  score: 34.3 bits;  conditional E-value: 1.8e-11
  NAD_binding_9   1 aivGaGprGlavlerLlarakkkspleitlfdp.sepgagrvwrtdqseelllNvpasemslftddp..........................ptf 69 
                    ai+GaG++Gla+++ L ++   ++  +i +f++ ++pg  + w+ + se     v++ ++++ ++++                          +++
     EEA21409.1  18 AIIGAGAAGLAAATYLSSE---EQFSHIEVFEQrNSPG--GTWNYS-SEKRAPKVTVPKTTPDDNNEtpyepassaddgfvsplyrdldtnipHSL 107
                    8******************...5999*******55555..778777.5566788888898887776688999999998888666655555554444 PP

  NAD_binding_9  70 aeWlrergaleeaeeldpddfvpRalyGrYlrdlfeellarlpegvtvevhra.evvdleeradgqavlladgasl.aadaVvLAlGh 155
                     ++ ++         + +  f++R ++ +Yl++++++l    + +++v+ +++ +    e+ + + + l+++++s+  +daVv+A Gh
     EEA21409.1 108 MNFSTQP------FPAGSPLFPSRDVVTEYLHQYAASLKHLIHYNTQVKNLTKiNLDGNECWELETQNLKTHETSIsIYDAVVVANGH 189
                    4444443......3567889*****************997777666666655524444444555555555666666599********9 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 2.5
  NAD_binding_9 135 avlladga.slaadaVvLAlGh 155
                    av+ ++g+ ++ +d+V+ ++G 
     EEA21409.1 287 AVRFSNGHiETGIDSVIFCTGY 308
                    5666677515799*******95 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0      0.04        48       5      37 ..      17      49 ..      13      56 .. 0.77
   2 !   26.6   0.0   2.5e-09     3e-06      89     215 ..     119     250 ..     104     277 .. 0.78
   3 ?   -0.8   0.0      0.55   6.6e+02     327     341 ..     295     309 ..     287     310 .. 0.79

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.04
  K_oxygenase  5 ligiGiGpsnLsLailleevkkelkalflerqp 37
                 +++iG+G++ L+ a  l++ ++  ++ ++e+++
   EEA21409.1 17 IAIIGAGAAGLAAATYLSSEEQFSHIEVFEQRN 49
                 678899999999999888888667777888875 PP

  == domain 2  score: 26.6 bits;  conditional E-value: 2.5e-09
  K_oxygenase  89 etflpsRkefedYlrWvasqleeqvrfgeeveevepdeeeeeelltveskd.aegeeeelearnlvlgvG..tepkiPev..lekle.gker.vvHss 179
                  +  +psR+  ++Yl+  a++l++ ++++++v++++  + +++e++++e+++ ++ e++     ++v++ G  +   iP++  +++++ + +  + Hs+
   EEA21409.1 119 SPLFPSRDVVTEYLHQYAASLKHLIHYNTQVKNLTKINLDGNECWELETQNlKTHETSISIYDAVVVANGhySDIFIPDIkgIKEFHeQYPGvISHSK 216
                  567899********************************9999*******997777778888899******5556679*97445665543344144555 PP

  K_oxygenase 180 eylerkeellakkriaVvGsGqSaaeifedllrrqk 215
                   y e   e+ + k+++VvG   S+ ++  ++++  +
   EEA21409.1 217 YYGEP--EDFKDKKVIVVGFSASGLDVSVQIAQLCQ 250
                  55554..599*****************999988754 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 0.55
  K_oxygenase 327 etlevdavvlATGYr 341
                   ++ +d v+++TGY+
   EEA21409.1 295 IETGIDSVIFCTGYH 309
                  56779*********8 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.0   9.6e-08   0.00011      19      58 ..      16      55 ..       4      62 .. 0.85
   2 !    5.7   0.0    0.0064       7.6       7      50 ..     216     259 ..     213     262 .. 0.86

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 9.6e-08
                EEEEE--SHHHHHHHHHHHHCTTS.-EEEEESSSS--TTTT CS
        Thi4 19 DvvivGaGssGLtaayylakkpdl.kvailersvspGGGaw 58
                 ++i+GaG++GL+aa yl+ + ++ ++ ++e++ spGG +w
  EEA21409.1 16 RIAIIGAGAAGLAAATYLSSEEQFsHIEVFEQRNSPGG-TW 55
                589****************996663799********87.44 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.0064
                 HHHHHHHHHTEEEEEEE--SHHHHHHHHHHHHCTTS-EEEEESS CS
        Thi4   7 ryfedllkyaesDvvivGaGssGLtaayylakkpdlkvailers 50 
                 +y+ +  ++ +  v++vG  +sGL  +  +a+  +  v++ er+
  EEA21409.1 216 KYYGEPEDFKDKKVIVVGFSASGLDVSVQIAQLCQHPVLVSERQ 259
                 566677899999*******************9988888888876 PP

>> MCRA  MCRA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   3.6e-06    0.0043       5      49 ..      18      60 ..      15      98 .. 0.88
   2 ?   -0.3   0.1      0.29   3.4e+02     214     275 ..     134     191 ..     126     194 .. 0.72

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 3.6e-06
                EEE--SHHHHHHHHHHHHTT---GGGEEEE-SS------------ CS
        MCRA  5 ylvGsGiasLaaAvyLirdakvpgenihileelkvaggsldgagd 49
                 ++G+G a+LaaA+yL  + ++  ++i ++e+ +++gg+++ +++
  EEA21409.1 18 AIIGAGAAGLAAATYLSSEEQF--SHIEVFEQRNSPGGTWNYSSE 60
                59**************999888..69************9887655 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.29
                 HHHHHTT-EEE-SEEEEEEEEEEE.TTEEEEEEEEEEE.TTEEEEEE--TTEEEEEE---SS CS
        MCRA 214 kyLkeqgVdfqfntkVtdiefeeeeedkktvteielekeegeeetieleedDlvfvtnGsit 275
                 +y  +    +++nt+V++++  +   d +   e+e+++   ++++ +++  D+v+v nG   
  EEA21409.1 134 QYAASLKHLIHYNTQVKNLTKINL--DGNECWELETQN--LKTHETSISIYDAVVVANGHYS 191
                 555555566789999999976643..457788888876..4555788888999999999765 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.1   0.2   3.1e-05     0.037       2      41 ..      17      58 ..      16      61 .. 0.76
   2 ?    3.0   0.0     0.035        42     144     204 ..     129     192 ..     113     211 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 3.1e-05
                   EEEE--SHHHHHHHHHHHHTTT..-EEEEESSSGGGSGGGG- CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGl..kvavvekeqefggataws 41
                   + +iG+G+AGLaAA+ ++ + +   + v e+ ++ gg+  +s
     EEA21409.1 17 IAIIGAGAAGLAAATYLSSEEQfsHIEVFEQRNSPGGTWNYS 58
                   67************9998876655666777777766666555 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.035
                    HHHHHHHHHTCTEEEEESEEEEEEEE...CTTEEEEEEEEETTTTCEEEEEESEEEE-----GG CS
  FAD_binding_2 144 larlvesarkagvdfqerteadeLiv...edgrvtGavvenpesgrevrirakavvlatgGfgr 204
                     + l+++a ++++ ++ +t++++L+    +++++   + +n+++ ++  +  +avv+a+g ++ 
     EEA21409.1 129 TEYLHQYAASLKHLIHYNTQVKNLTKinlDGNECWELETQNLKTHETSISIYDAVVVANGHYSD 192
                    456788888888999*********88654466999999999999999988888*******9986 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   8.3e-06    0.0099       2      36 ..      16      52 ..      15      58 .. 0.84
   2 ?   -2.9   0.0       1.7     2e+03     111     163 ..     128     188 ..     121     191 .. 0.48
   3 ?   -0.0   0.0      0.23   2.7e+02       2      34 ..     228     261 ..     227     264 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 8.3e-06
                 SEEEE--SHHHHHHHHHH..HHTT--EEEE-SSSSS- CS
  HI0933_like  2 dviviGgGaAGlmaAisa..akrgkrVlllekakklg 36
                 ++++iG+GaAGl aA  +  +++ +++ ++e+ +++g
   EEA21409.1 16 RIAIIGAGAAGLAAATYLssEEQFSHIEVFEQRNSPG 52
                 589************9884355557999999999987 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.7
                  HHHHHHHHHHHHT-EEE-S--EEEE...ECETTE.EEEEE......TTEEEEESEEEE--- CS
  HI0933_like 111 ivdallkelkeagvklrletevksv...ekeedgkfrvktk.....seeeleadklvlAtG 163
                  + + l + + + +  ++++t+vk++   + + ++  +++t+     +++    d++v+A G
   EEA21409.1 128 VTEYLHQYAASLKHLIHYNTQVKNLtkiNLDGNECWELETQnlkthETSISIYDAVVVANG 188
                  4456666666677777777777766322223333344444211111233333456666666 PP

  == domain 3  score: -0.0 bits;  conditional E-value: 0.23
                  SEEEE--SHHHHHHHHHHHHT.T--EEEE-SSSS CS
  HI0933_like   2 dviviGgGaAGlmaAisaakr.gkrVlllekakk 34 
                  +viv+G  a+Gl  ++++a+  ++ Vl+ e++++
   EEA21409.1 228 KVIVVGFSASGLDVSVQIAQLcQHPVLVSERQPS 261
                  89**************997752667888887766 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   0.0     0.001       1.3       1      34 [.      16      51 ..      16      60 .. 0.86
   2 ?   -1.1   0.0       2.4   2.8e+03      45      68 ..     131     154 ..     126     159 .. 0.74
   3 ?    4.1   0.0     0.057        69       1      36 [.     228     265 ..     228     276 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.001
                EEEEECSSHHHHHHHHHHHHTT..SEEEEEESSSSS CS
   Pyr_redox  1 kvvvvGgGyiglElAgalaelg..kkVtvversdkl 34
                +++++G+G  gl +A++l+     +++ v+e ++ +
  EEA21409.1 16 RIAIIGAGAAGLAAATYLSSEEqfSHIEVFEQRNSP 51
                79****************887756799999888776 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 2.4
                 HHHHHHHHTTEEEECSEEEEEEEE CS
   Pyr_redox  45 ilqeklekngievllntkveeieg 68 
                 +l+++   ++  +++nt+v+++++
  EEA21409.1 131 YLHQYAASLKHLIHYNTQVKNLTK 154
                 566666666777999999999875 PP

  == domain 3  score: 4.1 bits;  conditional E-value: 0.057
                 EEEEECSSHHHHHHHHHHHHTT.SEEEEEESSSSSS.T CS
   Pyr_redox   1 kvvvvGgGyiglElAgalaelg.kkVtvversdkll.r 36 
                 kv+vvG + +gl++   +a+l  + V v er++ ll +
  EEA21409.1 228 KVIVVGFSASGLDVSVQIAQLCqHPVLVSERQPSLLdP 265
                 79******************762677777888888833 PP

>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.0    0.0028       3.3       2      28 ..      25      53 ..      24      61 .. 0.91
   2 ?    4.6   0.0     0.014        16     213     259 ..     129     186 ..     116     191 .. 0.76

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0028
                   HHHHHHHHHHHTT..EEEEEEESSSSSBT CS
  Amino_oxidase  2 aGLaaArqLlsaG..fdVtvlEardrvGG 28
                   aGLaaA++L+s      + v+E r+ +GG
     EEA21409.1 25 AGLAAATYLSSEEqfSHIEVFEQRNSPGG 53
                   9********999998899**********9 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.014
                    HHHHHH..TTTTEEEETSEEEEEEEE...ETTC......EEEEETTSTEEEESEEEE- CS
  Amino_oxidase 213 pealae..elrgldirlntrVkeikr...egdg......vtvtledgevveaDaVvvT 259
                     e+l++   +++  i++nt Vk++++   +g++       +++++  +   +DaVvv+
     EEA21409.1 129 TEYLHQyaASLKHLIHYNTQVKNLTKinlDGNEcweletQNLKTHETSISIYDAVVVA 186
                    5666666668999**************9955554555335555555555599***998 PP

>> Glu_dehyd_C  Glucose dehydrogenase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00019      0.22      29      72 ..      12      54 ..       3      69 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00019
  Glu_dehyd_C 29 wepesalvlGaGslGLLalalleaeerglervyvlgrrdrpdpt 72
                 ++ ++  ++GaG+ GL a++ l++ e++++++ v+++r+ p+ t
   EEA21409.1 12 FKIDRIAIIGAGAAGLAAATYLSS-EEQFSHIEVFEQRNSPGGT 54
                 6667889***************96.799**********999766 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   0.00067       0.8       1      54 [.      16      66 ..      16      81 .. 0.81
   2 ?   -1.9   0.0       3.7   4.5e+03      65      83 ..     297     315 ..     281     321 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00067
                    EEEEETTTSHHHHHHHHHHHCTSSEEEEEEEESTTTTTSBHHHHSGGGTTTECE CS
  Semialdhyde_dh  1 kvaivGatGyvGqellrlLeehpevelvvllsssrsaGkklaeavkaleegkdl 54
                    ++ai+G  G+ G + +++L+++ +++ + ++ +++s G +++   +  +   ++
      EEA21409.1 16 RIAIIG-AGAAGLAAATYLSSEEQFSHIEVFEQRNSPGGTWNYSSE--KRAPKV 66
                    69****.8*******************************9988755..333333 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 3.7
                     TT-SEEEE-SCHHHHHHHH CS
  Semialdhyde_dh  65 kevdivflalpagvskela 83 
                      ++d v+++++  +s ++ 
      EEA21409.1 297 TGIDSVIFCTGYHYSFPFL 315
                     68999*****999987765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (475 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       507  (0.0282782); expected 358.6 (0.02)
Passed bias filter:                      466  (0.0259914); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 3193.09
//
Query:       EEA21410.1  [L=446]
Description: hypothetical protein PMAA_052190 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        1.5    8.7   9.1        1.8    8.4   3.4    2.4  2  DUF2721   Protein of unknown function (DUF2721)


Domain annotation for each model (and alignments):
>> DUF2721  Protein of unknown function (DUF2721)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.3    0.0044        80      74     105 ..      30      61 ..      25      72 .. 0.83
   2 ?    8.4   3.4    0.0001       1.8      72     126 ..     373     427 ..     365     429 .. 0.79

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.0044
     DUF2721  74 allvvlvvlllflsallsldlsllaailfvla 105
                 + l++++++++fl+ ++s++  ++   lf+ +
  EEA21410.1  30 LSLITTCMITIFLCTWVSIHPRVYTRQLFATS 61 
                 66889999999999999999888888888776 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0001
     DUF2721  72 lsallvvlvvlllflsallsldlsllaailfvlalllllvslllflrEirlslra 126
                 +sa++++ ++++ +  + + l+++ l++i+ + ++ l ++s +l+++E++ +lra
  EEA21410.1 373 VSAFVSIGSMIIFMHFEKVVLRWDGLVTIISLTSVGLYFLSRILMMAEVFAALRA 427
                 455555555555555455569******************************9997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (446 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       597  (0.033298); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.31s 00:00:00.87 Elapsed: 00:00:00.48
# Mc/sec: 2776.71
//
Query:       EEA21411.1  [L=368]
Description: abhydrolase domain-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.8e-12   47.0   1.9    7.6e-12   46.3   1.9    1.3  1  Abhydrolase_6  Alpha/beta hydrolase family
    3.5e-08   33.0   0.1    4.8e-08   32.6   0.1    1.2  1  Hydrolase_4    Serine aminopeptidase, S33
    8.2e-06   25.6   0.1    1.1e-05   25.3   0.1    1.2  1  Abhydrolase_1  alpha/beta hydrolase fold
  ------ inclusion threshold ------
      0.011   15.6   0.9      0.024   14.5   0.7    1.7  1  Abhydrolase_3  alpha/beta hydrolase fold
       0.17   10.5   0.0       0.31    9.6   0.0    1.4  1  AXE1           Acetyl xylan esterase (AXE1)


Domain annotation for each model (and alignments):
>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.3   1.9   2.1e-15   7.6e-12       1     136 [.     109     283 ..     109     328 .. 0.67

  Alignments for each domain:
  == domain 1  score: 46.3 bits;  conditional E-value: 2.1e-15
                    EEEE--GC......GCHHHHHHHHCCT...CEEEEE--TTSTS-GGCS--HHHCHHHHHHHCCTT......TTSEEEEEETCHHHHHHHHHHCC.. CS
  Abhydrolase_6   1 vlllHGagss.assWlvapLaallaag...vhvlapDlpGhGrsdpppldledladlaalldelaa....gggpvvlvGHSlGGalalaaapla.. 86 
                    +l +HGag++ +s+++v++ +al+a++    hvl++D++G+G+s+++p +   ++d + ++d   +     + ++ +++ S+G+a++ a   +   
     EEA21411.1 109 ILHMHGAGGTvGSGYRVPNYRALSAGQpdkSHVLTFDYRGFGHSTGSPSENGLILDALTVVDWAMNvagiPASRIAIFAQSMGTAVSIA---VSek 201
                    7899**998889***888999999999888777***********9999888888888888888777766557777**********7777...2223 PP

                    ..........EE.EEES-..............----TTTS----TTHHHHHHTT-CCCCHCCH...........S-HSCCCC CS
  Abhydrolase_6  87 ........lvvg.vlldppp............talpagllaaalelllallallrllawlsre...........plprlfla 136
                            + +g vl++p +            ++ p++ + a+++ll   l++++++ wls++           +++ ++++
     EEA21411.1 202 lalqsppvVFAGtVLVAPFVdcatlvstysvaGVIPLLAPLARFPLLFDHLRRFIRDNWLSKDriaqyvrsnedDYDIPWHH 283
                    3466679655669*****4444433333333333333333333333333333444478886654444333333323324444 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.6   0.1   1.3e-11   4.8e-08      33     119 ..     140     229 ..     107     284 .. 0.78

  Alignments for each domain:
  == domain 1  score: 32.6 bits;  conditional E-value: 1.3e-11
  Hydrolase_4  33 avyalDhrGhGrsegkrghvpsfddyvdDlaafvekvk..eehpelplfllGhSmGGliallyl.....lrypdkvaglilsaPalkikaklka 119
                  +v+++D+rG+G+s       ps + ++ D+ ++v+ +   +  p +++ ++++SmG ++++++      +  p  +ag +l+aP+++ ++ +++
   EEA21411.1 140 HVLTFDYRGFGHS----TGSPSENGLILDALTVVDWAMnvAGIPASRIAIFAQSMGTAVSIAVSeklalQSPPVVFAGTVLVAPFVDCATLVST 229
                  799**********....347889**********9887733566777***************9988877444444677**********9987632 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.3   0.1     3e-09   1.1e-05       4      95 ..     110     208 ..     107     251 .. 0.75

  Alignments for each domain:
  == domain 1  score: 25.3 bits;  conditional E-value: 3e-09
                    EEE-STTTCGGGGTTGHHHHHHHHT.....TSEEEEEEETTSTTSSSTTTGB.CHHSHHHHHHHHHHH..HHHCTTSSEEEEEETHHHHHHHHHHH CS
  Abhydrolase_1   4 vilhGlpgssdvwaerglapaLakd.....gfdvillDlrGvgySspapacinddygtasvaddldri..ldalgddkltlvGhSmGGmialayaa 92 
                    +  hG +g+ ++ ++  ++++ a +     + +v+++D rG+g+S+ +p++   +  + +   ++d++  ++  +  ++++ ++SmG++++ a+ +
     EEA21411.1 110 LHMHGAGGTVGSGYR--VPNYRALSagqpdKSHVLTFDYRGFGHSTGSPSE---NGLILDALTVVDWAmnVAGIPASRIAIFAQSMGTAVSIAVSE 200
                    556777775555333..3333333333333899*****************5...55677899****8878999999***************99988 PP

                    HH.....G CS
  Abhydrolase_1  93 ey.....p 95 
                    +      p
     EEA21411.1 201 KLalqspP 208
                    76555533 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.7   6.7e-06     0.024      49     114 ..     162     224 ..     109     235 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 6.7e-06
                    HHHHHHHHHHHHHTHHHHTETTCEEEEEEETHHHHHHHHHHHHHHHTT---..EEEEEEESE-SSTSS CS
  Abhydrolase_3  49 vedalaalrwlaeqawelgadpsrivlaGdSaGGnlaaavalrardegepk..vagqvliyPvtdler 114
                    + dal+++ w+ +    +g+ +sri+++ +S G   + av+ +++ ++ p+   ag+vl+ P +d  +
     EEA21411.1 162 ILDALTVVDWAMNV---AGIPASRIAIFAQSMGTAVSIAVSEKLALQS-PPvvFAGTVLVAPFVDC-A 224
                    57999******999...69**********************8888774.344699*******8887.3 PP

>> AXE1  Acetyl xylan esterase (AXE1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.0   8.8e-05      0.31     154     192 ..     161     199 ..     132     215 .. 0.93

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 8.8e-05
                 HHHHHHHHHHHHHTSTTEEEEEEEEEEETHHHHHHHHHH CS
        AXE1 154 vflDavrlveivaslpevDeeRvavlGasqGGalalava 192
                 + lDa  +v+ ++++  +  +R+a++ +s G a+++av+
  EEA21411.1 161 LILDALTVVDWAMNVAGIPASRIAIFAQSMGTAVSIAVS 199
                 679**********************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (368 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       402  (0.0224218); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2632.85
//
Query:       EEA21412.1  [L=694]
Description: mitochondrial carrier protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.2e-70  232.7   0.1    2.6e-24   84.9   0.0    3.4  3  Mito_carr  Mitochondrial carrier protein
    7.1e-16   58.4   2.4      4e-08   33.6   0.2    3.5  3  EF-hand_7  EF-hand domain pair
    1.8e-14   52.4   1.4      4e-06   26.3   0.1    5.3  5  EF-hand_6  EF-hand domain
    1.8e-13   49.0   5.6    1.1e-05   24.6   0.1    5.4  6  EF-hand_1  EF hand
    1.2e-06   27.7   2.1     0.0033   16.9   0.1    3.7  3  EF-hand_5  EF hand
    1.5e-06   28.0   5.6       0.34   10.8   0.0    5.4  6  EF-hand_8  EF-hand domain pair
  ------ inclusion threshold ------
      0.092   13.1   0.0        1.5    9.2   0.0    2.9  2  EF-hand_9  EF-hand domain


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.9   0.0     1e-27   2.6e-24       6      93 ..     345     433 ..     341     437 .. 0.91
   2 !   63.1   0.0   6.5e-21   1.7e-17       4      93 ..     442     530 ..     439     534 .. 0.91
   3 !   80.7   0.1   2.2e-26   5.7e-23       3      93 ..     539     628 ..     537     630 .. 0.94

  Alignments for each domain:
  == domain 1  score: 84.9 bits;  conditional E-value: 1e-27
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSS.HHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   6 lkellaGglagavatlvttPldvvKtrlqtqkksskksksaa.ildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrll 93 
                 ++++  G++aga+++++++P+d+vKtr+q+q++    +k ++  +d+ +k++++eG++gly+G++p+l++vap++a+k+++++ ++ + 
  EEA21412.1 345 AHHFGLGSIAGAFGAFMVYPIDLVKTRMQNQRSARPGEKLYNnSIDCARKVIRNEGIAGLYSGVIPQLIGVAPEKAIKLTVNDLVRGYA 433
                 68999***************************99877776667***************************************9988765 PP

  == domain 2  score: 63.1 bits;  conditional E-value: 6.5e-21
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   4 svlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrll 93 
                 ++  e+laG+ aga+++++t+Pl++vK+rlq+q++ +k+ + a   +    i+++ Gl gly+G+++ llr +p sa++f +y  lk  +
  EEA21412.1 442 KLPWEILAGASAGACQVVFTNPLEIVKIRLQVQGELAKNVEGA-PKRSAMWIVRNLGLIGLYKGASACLLRDVPFSAIYFPTYAHLKSDF 530
                 566689******************************9987765.888999**********************************999755 PP

  == domain 3  score: 80.7 bits;  conditional E-value: 2.2e-26
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   3 lsvlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrll 93 
                 l+vl+ l aG++ag+ a+ +ttP dv+Ktrlq++++++++++ ++++++ ++i+keeG++++++G  +++lr++p+ + ++++ye+l++ l
  EEA21412.1 539 LGVLQLLTAGAIAGMPAAYLTTPCDVIKTRLQVEARKGETKY-TSLRHCASTIMKEEGFKAFFKGGPARILRSSPQFGFTLAAYEVLQKAL 628
                 789999*******************************98855.55*****************************************99876 PP

>> EF-hand_7  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   0.1   7.2e-08   0.00019       7      70 ..      72     127 ..      66     128 .. 0.89
   2 !   33.6   0.2   1.5e-11     4e-08       2      68 ..     173     268 ..     173     271 .. 0.71
   3 !    8.3   0.0    0.0013       3.2      15      68 ..     257     307 ..     255     309 .. 0.86

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 7.2e-08
   EF-hand_7   7 aFkelDtdgdgyldkeellrllrkifqgagegsklsdeelellfkefDtdkdGvisfdEFlkly 70 
                  F   D++++g+++ ++   ++++       +++  d e e  f+ fD d+ G i f+ F+kly
  EEA21412.1  72 LFHVADRRRTGRINLTDWA-AFEN-----LLAKP--DAEYEIAFRLFDVDGTGAIKFETFKKLY 127
                 6999***************.9995.....45555..789**********************997 PP

  == domain 2  score: 33.6 bits;  conditional E-value: 1.5e-11
   EF-hand_7   2 eklkeaFkelDtdgdgyldkeellrllrkifqga...............gegsklsd.............eelellfkefDtdk.dGvisfdEFlk 68 
                 e++++aF ++D+dgdgy+ +e+++r++   + ++               + gsk+s              + ++ +++e  + + dG+i+++EFl+
  EEA21412.1 173 ERIRQAFHLFDKDGDGYIAPEDFQRIILETSKHKlsdyllehlptlcniSSGSKISYanvrafqniiremDIIDVILREATKKSsDGKITRTEFLN 268
                 689**********************6666665556777788888888885555544433333333332233388888888665538********86 PP

  == domain 3  score: 8.3 bits;  conditional E-value: 0.0013
   EF-hand_7  15 gdgyldkee.llrllrkifqgagegsklsdeelellfkefDtdk.dGvisfdEFlk 68 
                  dg+++++e l ++ r+      + s +++ e + lf+   +   +G++s+ +F k
  EEA21412.1 257 SDGKITRTEfLNEAARI-----TRFSQFTPMEADILFHFAGLEApSGRLSLKDFAK 307
                 69999****88878887.....9999999999999999998888689999999987 PP

>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0      0.36   9.3e+02       5      23 ..      72      90 ..      71      92 .. 0.86
   2 !   15.1   0.2   6.2e-06     0.016       5      27 ..     106     128 ..     102     135 .. 0.89
   3 !   26.3   0.1   1.5e-09     4e-06       1      26 [.     174     199 ..     174     207 .. 0.91
   4 ?    3.3   0.0     0.039        99      12      23 ..     256     267 ..     255     271 .. 0.87
   5 ?   -1.0   0.0      0.88   2.3e+03      14      26 ..     297     309 ..     295     313 .. 0.87

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.36
   EF-hand_6  5 aFklfDkdgdGkidaeElr 23
                +F+  D+ ++G i+  ++ 
  EEA21412.1 72 LFHVADRRRTGRINLTDWA 90
                69999********998875 PP

  == domain 2  score: 15.1 bits;  conditional E-value: 6.2e-06
   EF-hand_6   5 aFklfDkdgdGkidaeElrkalr 27 
                 aF+lfD+dg+G i +e ++k++ 
  EEA21412.1 106 AFRLFDVDGTGAIKFETFKKLYD 128
                 8******************9986 PP

  == domain 3  score: 26.3 bits;  conditional E-value: 1.5e-09
   EF-hand_6   1 elreaFklfDkdgdGkidaeElrkal 26 
                 ++r+aF+lfDkdgdG+i +e++++++
  EEA21412.1 174 RIRQAFHLFDKDGDGYIAPEDFQRII 199
                 689*******************9976 PP

  == domain 4  score: 3.3 bits;  conditional E-value: 0.039
   EF-hand_6  12 dgdGkidaeElr 23 
                 + dGki++ E+ 
  EEA21412.1 256 SSDGKITRTEFL 267
                 57********97 PP

  == domain 5  score: -1.0 bits;  conditional E-value: 0.88
   EF-hand_6  14 dGkidaeElrkal 26 
                 +G ++ +++ k++
  EEA21412.1 297 SGRLSLKDFAKVI 309
                 89*******9987 PP

>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0     0.037        96       5      23 ..      72      90 ..      71      92 .. 0.88
   2 !   15.5   0.2   3.5e-06    0.0088       3      25 ..     104     126 ..     102     129 .. 0.89
   3 !   24.6   0.1   4.5e-09   1.1e-05       2      26 ..     175     199 ..     174     202 .. 0.92
   4 ?   -2.8   0.1       2.5   6.5e+03       2      10 ..     235     243 ..     235     244 .. 0.85
   5 ?    3.9   0.0     0.018        45      13      23 ..     257     267 ..     255     268 .. 0.86
   6 ?   -2.0   0.0       1.3   3.4e+03      14      26 ..     297     309 ..     297     311 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.037
                HHHHHTTTSSSEEEHHHHH CS
   EF-hand_1  5 iFrefDkDgdGkIdfeEfk 23
                +F ++D+ ++G+I++ ++ 
  EEA21412.1 72 LFHVADRRRTGRINLTDWA 90
                5999**********99986 PP

  == domain 2  score: 15.5 bits;  conditional E-value: 3.5e-06
                 HHHHHHHTTTSSSEEEHHHHHHH CS
   EF-hand_1   3 keiFrefDkDgdGkIdfeEfkel 25 
                 + +Fr+fD+Dg+G I fe fk+l
  EEA21412.1 104 EIAFRLFDVDGTGAIKFETFKKL 126
                 669***************99986 PP

  == domain 3  score: 24.6 bits;  conditional E-value: 4.5e-09
                 HHHHHHHHTTTSSSEEEHHHHHHHH CS
   EF-hand_1   2 lkeiFrefDkDgdGkIdfeEfkell 26 
                 ++++F +fDkDgdG+I  e+f++++
  EEA21412.1 175 IRQAFHLFDKDGDGYIAPEDFQRII 199
                 899******************9986 PP

  == domain 4  score: -2.8 bits;  conditional E-value: 2.5
                 HHHHHHHHT CS
   EF-hand_1   2 lkeiFrefD 10 
                 +++i+re+D
  EEA21412.1 235 FQNIIREMD 243
                 6899***99 PP

  == domain 5  score: 3.9 bits;  conditional E-value: 0.018
                 SSSEEEHHHHH CS
   EF-hand_1  13 gdGkIdfeEfk 23 
                  dGkI++ Ef+
  EEA21412.1 257 SDGKITRTEFL 267
                 6*********7 PP

  == domain 6  score: -2.0 bits;  conditional E-value: 1.3
                 SSEEEHHHHHHHH CS
   EF-hand_1  14 dGkIdfeEfkell 26 
                 +G++++++f +++
  EEA21412.1 297 SGRLSLKDFAKVI 309
                 799******8875 PP

>> EF-hand_5  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.1      0.04     1e+02       4      16 ..     106     118 ..     104     125 .. 0.85
   2 !   16.9   0.1   1.3e-06    0.0033       1      24 [.     175     198 ..     175     200 .. 0.88
   3 !    5.5   0.0    0.0051        13      13      21 ..     258     266 ..     255     270 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.04
                 HHHHH-SS-SSCE CS
   EF-hand_5   4 tFqaiDlNgDGkI 16 
                 +F+ +D++g G I
  EEA21412.1 106 AFRLFDVDGTGAI 118
                 5*******96665 PP

  == domain 2  score: 16.9 bits;  conditional E-value: 1.3e-06
                 HHHHHHHH-SS-SSCE-HHHHHHH CS
   EF-hand_5   1 lkdtFqaiDlNgDGkIskeELktl 24 
                 ++++F  +D++gDG+I +e ++++
  EEA21412.1 175 IRQAFHLFDKDGDGYIAPEDFQRI 198
                 5678************99999984 PP

  == domain 3  score: 5.5 bits;  conditional E-value: 0.0051
                 SSCE-HHHH CS
   EF-hand_5  13 DGkIskeEL 21 
                 DGkI++ E+
  EEA21412.1 258 DGKITRTEF 266
                 ********9 PP

>> EF-hand_8  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0       0.1   2.6e+02      30      47 ..      71      88 ..      45      92 .. 0.84
   2 !   10.8   0.0   0.00013      0.34      27      52 ..     102     127 ..      98     130 .. 0.87
   3 !    7.0   0.1    0.0021       5.3      29      48 ..     176     195 ..     164     197 .. 0.82
   4 ?    3.8   0.0      0.02        52       2      27 ..     187     211 ..     186     215 .. 0.73
   5 ?   -3.5   0.0       3.9     1e+04      28      36 ..     235     243 ..     232     244 .. 0.85
   6 !    6.4   0.0    0.0032       8.1       2      34 ..     258     290 ..     257     309 .. 0.70

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.1
   EF-hand_8 30 ilfrefDtdgdGkisfeE 47
                ilf  +D+ + G+i++++
  EEA21412.1 71 ILFHVADRRRTGRINLTD 88
                799************998 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00013
   EF-hand_8  27 evdilfrefDtdgdGkisfeEFcvll 52 
                 e +i fr+fD dg G+i+fe F  l+
  EEA21412.1 102 EYEIAFRLFDVDGTGAIKFETFKKLY 127
                 67899***************999876 PP

  == domain 3  score: 7.0 bits;  conditional E-value: 0.0021
   EF-hand_8  29 dilfrefDtdgdGkisfeEF 48 
                 +  f +fD dgdG+i  e+F
  EEA21412.1 176 RQAFHLFDKDGDGYIAPEDF 195
                 556889*********88887 PP

  == domain 4  score: 3.8 bits;  conditional E-value: 0.02
   EF-hand_8   2 kgkItreelrril.rilglkkglseee 27 
                 +g+I +e+++ri+  +  ++ +ls++ 
  EEA21412.1 187 DGYIAPEDFQRIIlET-SKH-KLSDYL 211
                 899********99666.444.477765 PP

  == domain 5  score: -3.5 bits;  conditional E-value: 3.9
   EF-hand_8  28 vdilfrefD 36 
                 ++ ++re+D
  EEA21412.1 235 FQNIIREMD 243
                 7899****9 PP

  == domain 6  score: 6.4 bits;  conditional E-value: 0.0032
   EF-hand_8   2 kgkItreelrril.rilglkk..glseeevdilfre 34 
                 +gkItr+e+   + ri    +  ++++ e+dilf  
  EEA21412.1 258 DGKITRTEFLNEAaRIT---RfsQFTPMEADILFHF 290
                 89*******99663332...3667999999999965 PP

>> EF-hand_9  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.0   0.00057       1.5       3      60 ..      72     125 ..      71     130 .. 0.91
   2 ?   -0.6   0.0      0.65   1.7e+03       4      16 ..     179     191 ..     176     217 .. 0.65

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00057
   EF-hand_9   3 vFevcDtqktGrVpvsrlidyLravtaqdpeeseLeelakelDPdgedasvdldtflr 60 
                 +F+v D+ +tGr+ +++  ++    ++   +++e e   +++D dg  + ++++tf++
  EEA21412.1  72 LFHVADRRRTGRINLTDWAAFENLLAK---PDAEYEIAFRLFDVDGT-GAIKFETFKK 125
                 69***************9999988888...899999999*******9.99*****986 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.65
   EF-hand_9   4 FevcDtqktGrVp 16 
                 F+++D +  G ++
  EEA21412.1 179 FHLFDKDGDGYIA 191
                 6777766666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (694 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       339  (0.0189079); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.61u 0.23s 00:00:00.84 Elapsed: 00:00:00.41
# Mc/sec: 5095.95
//
Query:       EEA21413.1  [L=403]
Description: DNA N-glycosylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.2e-37  126.4   0.1      1e-36  125.7   0.1    1.3  1  OGG_N     8-oxoguanine DNA glycosylase, N-terminal domain
    1.6e-16   60.7   0.0    2.6e-16   60.0   0.0    1.3  1  HhH-GPD   HhH-GPD superfamily base excision DNA repair protei
     0.0054   16.5   0.0      0.012   15.4   0.0    1.6  1  HHH       Helix-hairpin-helix motif


Domain annotation for each model (and alignments):
>> OGG_N  8-oxoguanine DNA glycosylase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  125.7   0.1   1.7e-40     1e-36       1     121 []      10     135 ..      10     135 .. 0.93

  Alignments for each domain:
  == domain 1  score: 125.7 bits;  conditional E-value: 1.7e-40
                 EEEES-SS--HHHHHCSSS-SSEEE-.TTS-EEEEETTEEEEEEEETTEEEEET--.................HHHHHHTHHHHTTTTS-HHHHHHHHT CS
       OGG_N   1 kllvskeeldlkktLkcGQsFrWkkt.ekteyvgvlgdrvveLkqeeddllyrtlesess....tkasseeakeeeteeilrdYfnLdvdleelykews 94 
                 kl++s +el++++tL+cGQsFrW++  +++e+++vl++r+v+L+q+++ l+yr + ++++     + + +  +++et+ei+++Y+nL  +l++ly++ws
  EEA21413.1  10 KLPISLSELCINTTLRCGQSFRWQQRpDSDEWRCVLRGRLVSLRQDQSYLYYRSCTPHKPtssvPTMNGTVNTSDETREIVTHYLNLTSNLTDLYNQWS 108
                 68999*******************9966667*************************999877775666777889999********************** PP

                 T.SHHHHHHHCCTTT-------HHHHH CS
       OGG_N  95 kkdplfkksadkftGiRllrqdpwEcL 121
                  +dp+fkk+a++ftGiR+lrqd wE+L
  EEA21413.1 109 DSDPNFKKKAPNFTGIRILRQDAWEAL 135
                 *************************98 PP

>> HhH-GPD  HhH-GPD superfamily base excision DNA repair protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.0   0.0   4.4e-20   2.6e-16       1      91 [.     136     296 ..     136     318 .. 0.94

  Alignments for each domain:
  == domain 1  score: 60.0 bits;  conditional E-value: 4.4e-20
                 HHHHHHTTS-HHHHHHHHHHHHHHHS.............HCSHHHHHHSH.HHHHHHHHTTSTTHHHHHHHHHHHHHHHH................... CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxx.............xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxx................... RF
     HhH-GPD   1 vsailsqqtsderanriierlferfg.............fptpedladad.eekLrelirelGfyrrKakyikelArilv................... 66 
                 vs+i+s++++++r+ +++e+l++++g             fp pe+l++ d e+ Lrel    Gf+ ++akyi ++A ++                    
  EEA21413.1 136 VSFICSSNNNIARISQMVEKLCANYGdlvatiddrsyhdFPAPEALTGKDvEARLREL----GFG-YRAKYIYQTAVMVSekekgwldslrnpespafg 229
                 89********************************************************....***.********************************* PP

                 .............................................S-SSS--TTSHHHHHHHHHHTTSSS CS
                 .............................................xxxxxxxxxxxxxxxxxxxxxxxxx RF
     HhH-GPD  67 .............................................gkpdvlivvDvhvrrilkrlrsike 91 
                                                              g   ++++vD+hv++i++r +   +
  EEA21413.1 230 vapsqggemrpegregyrdahekllelqgvgpkvadcvclmglgwG---EAVPVDTHVWQIAQRDYKFGK 296
                 *****************************************99555...69999**********997655 PP

>> HHH  Helix-hairpin-helix motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   2.1e-06     0.012      10      28 ..     250     268 ..     244     270 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 2.1e-06
                 HHHHHTSTT-SHHHHHHHH CS
         HHH  10 reeLlalPGVGpktAeaIl 28 
                  e Ll+l GVGpk+A++++
  EEA21413.1 250 HEKLLELQGVGPKVADCVC 268
                 689*************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (403 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       612  (0.0341346); expected 358.6 (0.02)
Passed bias filter:                      503  (0.0280551); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 2882.98
//
Query:       EEA21414.1  [L=551]
Description: splicing factor u2af large subunit [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.1e-26   90.1   0.0    3.1e-10   39.7   0.0    3.6  3  RRM_1         RNA recognition motif. (a.k.a. RRM, RBD, or RNP
    7.1e-05   22.6   0.0       0.42   10.5   0.0    3.2  3  RRM_occluded  Occluded RNA-recognition motif


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   1.9e-06     0.017       2      67 ..     228     297 ..     227     299 .. 0.87
   2 !   39.7   0.0   3.4e-14   3.1e-10       1      69 [.     346     415 ..     346     416 .. 0.97
   3 !   31.1   0.0   1.7e-11   1.5e-07      13      69 ..     476     536 ..     470     537 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.9e-06
                 EEESETTTSSHHHHHHHHH....TTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTE CS
       RRM_1   2 fVgnLppdvteeeLkelFs....kfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggr 67 
                 f  nLpp+vt+  L  +F+    + + i+ i+ +   +  k + fa  eF+ + +A+ Al+ l+g  ++ +
  EEA21414.1 228 FAYNLPPNVTDAALISFFNlqlnGLNVIEGIDPCVSsQISKDHAFALLEFKGPNEATVALA-LDGISMEEH 297
                 667***************644437899999999999999999*******************.***887766 PP

  == domain 2  score: 39.7 bits;  conditional E-value: 3.4e-14
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrel 69 
                 l V+n+p ++ ee + +l++ +G+ + + lv+d  t+ s+g+af+e+ +  + + A+e+lng++lg++ l
  EEA21414.1 346 LCVTNIPLYIPEEPVTMLLKSIGELRAFVLVKDsGTDESRGIAFCEYVDATATAIAVESLNGMELGDKHL 415
                 579***************************************************************9987 PP

  == domain 3  score: 31.1 bits;  conditional E-value: 1.7e-11
                 HHHHHHHHTTSCEEEEEEEEE..TTTSEEEEE..EEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1  13 eeLkelFskfGpiksiklvrd..etgkskgfa..fVeFeskedAekAlealngkklggrel 69 
                 e++ +  sk+G++ ++k++r     ++s g++  fV+F++ e+A++Al+al g+k+ +r++
  EEA21414.1 476 EDVQDECSKYGQVLDLKIPRPagGSRQSAGVGkiFVKFDTVESATNALKALAGRKFSDRTV 536
                 6888999*************98866777766666************************997 PP

>> RRM_occluded  Occluded RNA-recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.4   0.0   0.00043       3.9       7      66 ..     230     297 ..     225     303 .. 0.84
   2 !   10.5   0.0   4.7e-05      0.42       4      71 ..     346     418 ..     343     421 .. 0.88
   3 ?   -0.1   0.0     0.095   8.5e+02      43      68 ..     511     536 ..     509     540 .. 0.89

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.00043
  RRM_occluded   7 lplsDtvnkariralveek.........egeikkivLvpdheGAivefkdekiagkasLaLdgsefegk 66 
                   ++l+ +v++a + ++++ +          ++ +  ++  dh  A++efk  + a  ++LaLdg+++e++
    EEA21414.1 230 YNLPPNVTDAALISFFNLQlnglnviegIDPCVSSQISKDHAFALLEFKGPNEA-TVALALDGISMEEH 297
                   7888889998888888888888888765588999999************99886.699*****998765 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 4.7e-05
  RRM_occluded   4 isllplsDtvnkariralveekegeikkivLvpdheG......AivefkdekiagkasLaLdgsefegkklrcG 71 
                   +++ +++  + ++ ++ l+++  ge++  vLv d +       A+ e+ d+++++ a+ +L+g+e+ +k+l++ 
    EEA21414.1 346 LCVTNIPLYIPEEPVTMLLKSI-GELRAFVLVKDSGTdesrgiAFCEYVDATATAIAVESLNGMELGDKHLKIT 418
                   7899999999************.*********99754444446****************************987 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.095
  RRM_occluded  43 vefkdekiagkasLaLdgsefegkkl 68 
                   v+f+ +++a  a+ aL g +f+++++
    EEA21414.1 511 VKFDTVESATNALKALAGRKFSDRTV 536
                   8999*****************99986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (551 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       500  (0.0278878); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.23s 00:00:00.80 Elapsed: 00:00:00.41
# Mc/sec: 4027.84
//
Query:       EEA21415.1  [L=556]
Description: splicing factor u2af large subunit [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.3e-26   90.0   0.0    3.1e-10   39.7   0.0    3.6  3  RRM_1         RNA recognition motif. (a.k.a. RRM, RBD, or RNP
    6.7e-05   22.7   0.0       0.43   10.5   0.0    3.2  3  RRM_occluded  Occluded RNA-recognition motif


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   1.9e-06     0.017       2      67 ..     228     297 ..     227     299 .. 0.87
   2 !   39.7   0.0   3.5e-14   3.1e-10       1      69 [.     346     415 ..     346     416 .. 0.97
   3 !   31.1   0.0   1.7e-11   1.5e-07      13      69 ..     476     536 ..     470     537 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.9e-06
                 EEESETTTSSHHHHHHHHH....TTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTE CS
       RRM_1   2 fVgnLppdvteeeLkelFs....kfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggr 67 
                 f  nLpp+vt+  L  +F+    + + i+ i+ +   +  k + fa  eF+ + +A+ Al+ l+g  ++ +
  EEA21415.1 228 FAYNLPPNVTDAALISFFNlqlnGLNVIEGIDPCVSsQISKDHAFALLEFKGPNEATVALA-LDGISMEEH 297
                 667***************644437899999999999999999*******************.***887766 PP

  == domain 2  score: 39.7 bits;  conditional E-value: 3.5e-14
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrel 69 
                 l V+n+p ++ ee + +l++ +G+ + + lv+d  t+ s+g+af+e+ +  + + A+e+lng++lg++ l
  EEA21415.1 346 LCVTNIPLYIPEEPVTMLLKSIGELRAFVLVKDsGTDESRGIAFCEYVDATATAIAVESLNGMELGDKHL 415
                 579***************************************************************9987 PP

  == domain 3  score: 31.1 bits;  conditional E-value: 1.7e-11
                 HHHHHHHHTTSCEEEEEEEEE..TTTSEEEEE..EEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1  13 eeLkelFskfGpiksiklvrd..etgkskgfa..fVeFeskedAekAlealngkklggrel 69 
                 e++ +  sk+G++ ++k++r     ++s g++  fV+F++ e+A++Al+al g+k+ +r++
  EEA21415.1 476 EDVQDECSKYGQVLDLKIPRPagGSRQSAGVGkiFVKFDTVESATNALKALAGRKFSDRTV 536
                 6888999*************98866777766666************************997 PP

>> RRM_occluded  Occluded RNA-recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.4   0.0   0.00044       3.9       7      66 ..     230     297 ..     225     303 .. 0.84
   2 !   10.5   0.0   4.8e-05      0.43       4      71 ..     346     418 ..     343     421 .. 0.88
   3 ?    0.1   0.0     0.084   7.5e+02      43      69 ..     511     537 ..     509     543 .. 0.89

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.00044
  RRM_occluded   7 lplsDtvnkariralveek.........egeikkivLvpdheGAivefkdekiagkasLaLdgsefegk 66 
                   ++l+ +v++a + ++++ +          ++ +  ++  dh  A++efk  + a  ++LaLdg+++e++
    EEA21415.1 230 YNLPPNVTDAALISFFNLQlnglnviegIDPCVSSQISKDHAFALLEFKGPNEA-TVALALDGISMEEH 297
                   7888889998888888888888888765588999999************99886.699*****998765 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 4.8e-05
  RRM_occluded   4 isllplsDtvnkariralveekegeikkivLvpdheG......AivefkdekiagkasLaLdgsefegkklrcG 71 
                   +++ +++  + ++ ++ l+++  ge++  vLv d +       A+ e+ d+++++ a+ +L+g+e+ +k+l++ 
    EEA21415.1 346 LCVTNIPLYIPEEPVTMLLKSI-GELRAFVLVKDSGTdesrgiAFCEYVDATATAIAVESLNGMELGDKHLKIT 418
                   7899999999************.*********99754444446****************************987 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.084
  RRM_occluded  43 vefkdekiagkasLaLdgsefegkklr 69 
                   v+f+ +++a  a+ aL g +f+++++ 
    EEA21415.1 511 VKFDTVESATNALKALAGRKFSDRTVV 537
                   8999*****************999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (556 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       507  (0.0282782); expected 358.6 (0.02)
Passed bias filter:                      309  (0.0172346); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.32s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 3633.97
//
Query:       EEA21416.1  [L=507]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    0.00012   21.5   9.7    0.00012   21.5   9.7    1.9  2  7tm_2      7 transmembrane receptor (Secretin family)
  ------ inclusion threshold ------
        1.1    8.3  12.1       0.64    9.1   8.3    2.0  2  Dicty_CAR  Slime mold cyclic AMP receptor


Domain annotation for each model (and alignments):
>> 7tm_2  7 transmembrane receptor (Secretin family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   9.7   1.3e-08   0.00012       7     153 ..      58     211 ..      55     244 .. 0.79
   2 ?   -0.9   0.3     0.089   7.9e+02     164     221 ..     293     373 ..     288     389 .. 0.50

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 1.3e-08
                 HHHHH.HHHHHHHHHHHHHHHHTTTGTTSH.HHHHHHHHHHHHHHHHHHHHHHHHHHTTTTEEEEEHH....HHHHHHHHHHHHHHHHHHHHHHHHHHH CS
       7tm_2   7 ittvG.lslSlvaLlvallilllfrklrct.rnyihlnLflslllrailvlvkdavlkseedeseaev....ekvgCkvvavflhYfllanffWllvEg 99 
                 it vG l++ l+ L++ l++  ++  ++ t rnyi + + ls ++ +i +++   +  ++ ++  + +    +  +C+ + ++l +  +a+ +W l+  
  EEA21416.1  58 ITAVGwLAVALLPLTIFLFVSYAVLPVKFTnRNYITVCFTLSCVCLQIPFIIPLGTKPQQCNDPIT-PndmnTDWSCAFTGAILLFGGIACVTWSLLRT 155
                 5666623566666666666666777777667*********************99888773333222.123446778*********************** PP

                 HHHHHHHHT-XXSHHHCHHHHHHHHTHHHHHHHHHHHHHHHHHS-..SSSS---SS CS
       7tm_2 100 lylytllveaffserkylkkylliGwGvPavvvavwavvkayled..erCWlsnee 153
                 + l++ +   +      ++  +++G GvP++++++++v+ ++++     C +++++
  EEA21416.1 156 IALHLQVCWEVVIGPVFMWISFAVGLGVPVLILTLMLVFTGVSYRfgGVCHINSKN 211
                 ************************************99966554411557666665 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.089
                 HHHHHHHHHHHHHHHHHHHHHHHTTSS-TTSHH.........................HHHHHHHHHHHHHHHHHHHHHHH CS
       7tm_2 164 lliilvNfilfinivrvlvqklkesnkeekdlkka.......................lklvkstlvllpLlgityvvfav 221
                 +++il N+i + +++ +l + l+ + ++ ++ +                           ++ ++lvll++ +    +f+v
  EEA21416.1 293 VMVILANVIYLSVTFLQLDSDLTLNAANLAKAQPWltclatlrdptkcaseasalgltEAALDAALVLLCIASFWNFIFTV 373
                 455555665555555555555554444444433334455555555544444444444334444555555554444445544 PP

>> Dicty_CAR  Slime mold cyclic AMP receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   1.0     0.039   3.5e+02      90     131 ..      62     103 ..      58     115 .. 0.78
   2 ?    9.1   8.3   7.2e-05      0.64      65     186 ..     122     241 ..      88     263 .. 0.74

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.039
   Dicty_CAR  90 cwlwtlclalsiynlivkrepepekf.ekyyfvlcwglplist 131
                  wl   +l l+i+++ v     p kf ++ y ++c++l  ++ 
  EEA21416.1  62 GWLAVALLPLTIFLF-VSYAVLPVKFtNRNYITVCFTLSCVCL 103
                 588888999999855.66677888884688999***9988774 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 7.2e-05
   Dicty_CAR  65 lleeaqesgfqcylyaivitygslacwlwtlclalsiynlivkrepepekfekyyfvlcwglplistivml.skkvievvgnwcwigekyvgyrfglfy 162
                 ++ ++ ++ + c +   ++ +g +ac  w+l+ ++++++ +         f    f++  g+p+++  +ml  + v    g+ c i++k + +    ++
  EEA21416.1 122 ITPNDMNTDWSCAFTGAILLFGGIACVTWSLLRTIALHLQVCWEVVIGPVFMWISFAVGLGVPVLILTLMLvFTGVSYRFGGVCHINSKNSLHD---YW 217
                 447788999*****************************999999999999*************76655555156777789******98765443...45 PP

   Dicty_CAR 163 gpfliiwaisavlvgltsrytykv 186
                  p l+  ++  vl  +t  y  +v
  EEA21416.1 218 LPALVFGGMGLVLQFVTMGYCIHV 241
                 566666666666666666666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (507 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       853  (0.0475766); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.31s 00:00:00.94 Elapsed: 00:00:00.49
# Mc/sec: 3116.40
//
Query:       EEA21417.1  [L=558]
Description: MFS quinate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-77  261.4  25.7    1.9e-77  261.1  25.7    1.1  1  Sugar_tr  Sugar (and other) transporter
    1.1e-12   47.6  68.0    1.3e-11   44.1  36.8    2.3  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
       0.11   12.2   1.5        7.2    6.5   0.0    2.7  2  DDDD      Putative mitochondrial precursor protein
        1.9    8.6  11.5       0.83    9.8   0.7    3.3  3  DUF2456   Protein of unknown function (DUF2456)


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  261.1  25.7   4.3e-81   1.9e-77       8     452 .]      38     510 ..      30     510 .. 0.90

  Alignments for each domain:
  == domain 1  score: 261.1 bits;  conditional E-value: 4.3e-81
                 HHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGG CS
    Sugar_tr   8 ggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevli 106
                  g   g d g+i+++ ++ +f++  ++++++ + e ++   g +++++++G++ G+lfa l+ dr+GR ++    +vl + g+++ +      s+ +++
  EEA21417.1  38 MGAARGVDEGLISGAFNSKDFQNYINYQSYS-KVE-QTNIKGNVTAMVQIGSVGGALFAFLVCDRIGRIWATRQLCVLWILGIAIFMGNG--GSLGAVY 132
                 46788999************66555555555.455.47999*****************************************99988877..68***** PP

                 GGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHH.HTSS-..TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHHTT CS
    Sugar_tr 107 vgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglgl.nktsn..adgwrillglqlvpallllilllflPESPrylvekg 202
                 +gR+++G+gvG + v++P+y++EiAp+++Rg ++ ++  ++ +Gi++a++ ++g   + ++  +++w ++  l +++a ++++l ++  ESPrylv+ g
  EEA21417.1 133 AGRFIAGLGVGQTVVVAPVYLAEIAPTSIRGLCTCVFTGFVYLGIVLAYFANYGCqVNLGDttHNRWLVPTSLHIMFAGIIFLLSFLQSESPRYLVKSG 231
                 ******************************************************9655555899*********************************** PP

                 -HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH..............HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH... CS
    Sugar_tr 203 keeeakevlaklrgeedadrelaeekdsleaeqeee.........kaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsks... 289
                 + e+a ++la++rg + ++++++ e+ ++ea+  +e            +ke +   ++++r+ + ++ q++ q +G  +i+ y+p +f+ lg++     
  EEA21417.1 232 QIEKAIATLARVRGLPSDHEYIVREVGMIEATHHAEmeatmgsgpIGVLKEAFLIPSNLYRVYLTFMAQVLSQWSGAGSITVYAPDLFRLLGITGNneg 330
                 *******************************999999999986655555666666669************************************9999* PP

                 HHHHHHHHHHHHHH.HHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS................CHHHHHHHHHHHHHHHTTTTHHHHHH CS
    Sugar_tr 290 llvtiivgvvnfva.tfvaiflvdrfGRRtllllGaagmaicfvilgivalllvaks.............kaasivaivfialfialfalgwgpvpwvl 374
                 llv++++g+++ +a +++a+flvd +GR++ lllG++ +ai +++++  a+l++  +             k+as +aiv+i+l  +  algw+++ ++l
  EEA21417.1 331 LLVSAVFGIIKLIAaVVCALFLVDVIGRKRALLLGITLQAISMIYIA--AFLTSVPQmgvvsgfklpisqKGASTGAIVMIYLSGVGWALGWNSMQYLL 427
                 **********977516778***************************9..44444444456667799999****************************** PP

                 HHHHSHTTTHHHHHHHHHHHHHHHHH.....HHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 375 vsElfpqsvRskalaiavavnwlanf.....lisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                  +Elfp+++R++++++a+++++  ++     + ++l p+ ++ i   ++f+ fa++ +++ i+v+f +pet+gr+le +++lf
  EEA21417.1 428 TAELFPLRIRALCTSMAMTLHFANQYgnsraVPNMLLPVSQGGIDPKGTFWCFAAITIIGGIWVWFSIPETAGRSLESMDRLF 510
                 ******************999987652222277888888889999***********************************997 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.1  36.8   2.8e-15   1.3e-11      33     327 ..      71     429 ..      31     450 .. 0.75
   2 !   17.8  23.2   2.9e-07    0.0013       2     182 ..     297     503 ..     296     525 .. 0.73

  Alignments for each domain:
  == domain 1  score: 44.1 bits;  conditional E-value: 2.8e-15
       MFS_1  33 e....igllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.sslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigl 125
                 e     g +++++ +g++ ++l++  + dr+Gr +      +l++lg ++++++  ++  +++++r+++Glg g  + ++ +++a+++p + rg+ + +
  EEA21417.1  71 EqtniKGNVTAMVQIGSVGGALFAFLVCDRIGRIWATRQLCVLWILG-IAIFMGnGGSLgAVYAGRFIAGLGVGQTVVVAPVYLAEIAPTSIRGLCTCV 168
                 2333466799*************************9999999*****.555556656666*************************************** PP

       MFS_1 126 lsagfslGailgpllggllasslg......Wravfyilaivsllafvlfllllpeepperkrkspkeee.............................. 188
                 +++++ lG++l++ +   +  +lg      W ++  ++  ++ + f+l   +l  e p+   ks++ e+                              
  EEA21417.1 169 FTGFVYLGIVLAYFANYGCQVNLGdtthnrWLVPTSLHIMFAGIIFLL--SFLQSESPRYLVKSGQIEKaiatlarvrglpsdheyivrevgmieathh 265
                 ************666666669999****99999999999999999885..5554444444444444444799999999999999999999999876666 PP

       MFS_1 189 ...kgtgpaplvp.........awkallkdpvlw....illialllfffgfsglltllplylqevlgls....glllaglllallalvgailallagrl 267
                    +                  + +a+l +  l+     +++ +l+ + g  +++++ p  l   lg++    g ll++++++++ l++a++  +a +l
  EEA21417.1 266 aemE--------AtmgsgpigvLKEAFLIPSNLYrvylTFMAQVLSQWSGAGSITVYAPD-LFRLLGITgnneG-LLVSAVFGIIKLIAAVV--CALFL 352
                 6662........23333333334455555555534333455555555667777*******.59******87777.66666777777777666..77777 PP

       MFS_1 268 sdrlgrrrrlllallllllaalglallavt.................ssavllllvlvliGfglgfvfpsllalasd 327
                 +d +gr+r+lll++ l +++ + +a + ++                   ++ ++++++l G+g+++ + s+++l++ 
  EEA21417.1 353 VDVIGRKRALLLGITLQAISMIYIAAFLTSvpqmgvvsgfklpisqkGASTGAIVMIYLSGVGWALGWNSMQYLLTA 429
                 7**************99999998888888888999999999999888777777779999********8888877653 PP

  == domain 2  score: 17.8 bits;  conditional E-value: 2.9e-07
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltl.yalgaavaslpl.GrlsdrfGrrrvlllglllfalg.lllllfass............. 84 
                 ++a++ls ++ +  ++++ + l + lgi++   gll+++ +++  ++a+++   +l+d +Gr+r lllg++l a++ +++++f +s             
  EEA21417.1 297 FMAQVLSQWSGAGSITVYAPDLFRLLGITGNNEGLLVSAvFGIIKLIAAVVCaLFLVDVIGRKRALLLGITLQAISmIYIAAFLTSvpqmgvvsgfklp 395
                 78899999999998888888999************888868888888888886889********************66666674441223333334444 PP

       MFS_1  85 ......lwlllvlrvlqGlgagalfpagaal.iadwfpkeergraigllsa.........gfslGailgpllggllasslgWravfyilaivsllafvl 167
                       ++  +v+  l+G+g ++++ ++++l +a++fp + r++ ++++++         + ++  +l p+  g +       ++f+ +a++++++++ 
  EEA21417.1 396 isqkgaSTGAIVMIYLSGVGWALGWNSMQYLlTAELFPLRIRALCTSMAMTlhfanqygnSRAVPNMLLPVSQGGID----PKGTFWCFAAITIIGGIW 490
                 434443335888888*************9972589****************99955553333333366666666666....999999999999999993 PP

       MFS_1 168 fllllpeepperkrk 182
                   +++  ++++ +  
  EEA21417.1 491 --VWFSIPETAGRSL 503
                 ..5555554444443 PP

>> DDDD  Putative mitochondrial precursor protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.0    0.0016       7.2      32      63 ..      33      64 ..      31      67 .. 0.92
   2 ?    3.0   1.2     0.019        83      33      61 ..     336     364 ..     333     367 .. 0.89

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0016
        DDDD 32 tpFgLlrvilvVipgllvGtliSknvAnlLee 63
                ++FgL++    V  gl+ G+  Sk++ n++++
  EEA21417.1 33 ISFGLMGAARGVDEGLISGAFNSKDFQNYINY 64
                79*************************99887 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.019
        DDDD  33 pFgLlrvilvVipgllvGtliSknvAnlL 61 
                  Fg++++i++V+  l++  +i ++ A lL
  EEA21417.1 336 VFGIIKLIAAVVCALFLVDVIGRKRALLL 364
                 6***************9999999988877 PP

>> DUF2456  Protein of unknown function (DUF2456)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.4    0.0046        21      33      61 ..     102     130 ..      88     140 .. 0.83
   2 ?    9.8   0.7   0.00019      0.83      23      85 ..     153     216 ..     143     219 .. 0.88
   3 ?   -3.2   0.3       2.1   9.4e+03      73      85 ..     339     351 ..     331     356 .. 0.73

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0046
     DUF2456  33 glllsviiflvlWpvtigilagigkklgs 61 
                 g +++    +vlW++ i+i  g g +lg 
  EEA21417.1 102 GRIWATRQLCVLWILGIAIFMGNGGSLGA 130
                 8899999***************9998885 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00019
     DUF2456  23 iewlvskairglllsviiflvlWpvtigilagigkklgs.dyyfnntwapqviKlvygvvlgli 85 
                 ++ +  + irgl ++v++++v+  + ++  a  g ++   d  +n + +p+ + ++++ ++ l+
  EEA21417.1 153 LAEIAPTSIRGLCTCVFTGFVYLGIVLAYFANYGCQVNLgDTTHNRWLVPTSLHIMFAGIIFLL 216
                 55567789************************98877777******************998776 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 2.1
     DUF2456  73 viKlvygvvlgli 85 
                 +iKl+ +vv++l+
  EEA21417.1 339 IIKLIAAVVCALF 351
                 6777777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (558 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       621  (0.0346366); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.46
# Mc/sec: 3630.51
//
Query:       EEA21418.1  [L=461]
Description: monoxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.1e-20   74.2   0.0    4.5e-20   72.2   0.0    1.9  1  FAD_binding_3  FAD binding domain
    2.5e-08   33.5   0.0     0.0012   18.1   0.0    2.3  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    3.7e-07   29.6   0.3      6e-07   28.9   0.3    1.2  1  FAD_binding_2  FAD binding domain
    8.1e-06   24.8   0.2    0.00064   18.5   0.3    2.1  2  HI0933_like    HI0933-like protein
    1.3e-05   25.3   0.3    3.1e-05   24.1   0.3    1.7  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
      0.002   17.3   0.3     0.0045   16.1   0.3    1.6  1  GIDA           Glucose inhibited division protein A
      0.003   18.1   0.4       0.14   12.7   0.6    2.5  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
     0.0099   15.5   0.1      0.074   12.6   0.3    2.0  2  DAO            FAD dependent oxidoreductase
  ------ inclusion threshold ------
      0.012   14.9   0.4      0.019   14.2   0.4    1.3  1  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
      0.025   13.8   0.1      0.045   13.0   0.1    1.3  1  Thi4           Thi4 family
        0.1   12.5   0.0       0.63   10.0   0.0    2.3  3  DUF1344        Protein of unknown function (DUF1344)
       0.18   11.1   0.4        2.5    7.3   0.0    2.6  3  Amino_oxidase  Flavin containing amine oxidoreductase
       0.21   10.8   0.0       0.36   10.1   0.0    1.3  1  AlaDh_PNT_C    Alanine dehydrogenase/PNT, C-terminal domain
       0.25   10.6   0.2        0.4   10.0   0.2    1.3  1  FAD_oxidored   FAD dependent oxidoreductase


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.2   0.0   3.6e-23   4.5e-20       2     319 ..      15     334 ..      14     354 .. 0.73

  Alignments for each domain:
  == domain 1  score: 72.2 bits;  conditional E-value: 3.6e-23
                    EEEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSSS--EEEHHHHHHHHHTT-HHHHHHHSEECCCCEEEEEEECCCCCEEEEEHHCHHCST CS
  FAD_binding_3   2 tdVlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlpradglnqrtmellrqlGledrilaegapnelmgealynelsdtpkaradlelesspe 97 
                    t V+IVGaG+ Gl  a+ ++ aG +v++ ek ++  +l+ + gl +  + ll+  Gl ++++a g++n +m++  + +         ++ + +  +
     EEA21418.1  15 TRVIIVGAGLGGLACAMAMHYAGFEVIVFEKVREFLRLGDSLGLGENALKLLKRWGLYEELIAIGNKNPVMNIRRWDD--------GKIMATQPLM 102
                    89**************************************************************************99........4444467777 PP

                    -CEE--HHH..HHHHHHHHHHHHTEEETCSEEEECCEECCCCCCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHH.HTGG.EEEEEEE..EEEEE CS
  FAD_binding_3  98 rvtvypqte..leriLvehaeerglqvrfktevesleqdeegvtaevrdketgeeetvrakYlvGaDGgrStvrkt.lgie.fegeetv..yeagv 187
                    +++ y  ++     + +++ ++ g+ +++++e++s+ +d  +v  +++d +     t+ a+ +vGaDG +S++r+  lg++  + +++   y+a +
     EEA21418.1 103 DMAGYIGHRgdYHVAFINRVKQLGIPINMGHEIVSFDEDAPSV--TLKDGR-----TFYADLIVGADGIKSRARELvLGFSdAPKSSGYacYRAYF 191
                    888887665115567789999*************998887775..455553.....8*****************9636888544444331133333 PP

                    .EEEEEEC.-SCCCTTC...CEEEEECCTTEE.EEEECCETEEEEEEEEECCE-GGGS...CCCHHHHHHHHHHHHHHTTSSCEE.EEEEEEEEEE CS
  FAD_binding_3 188 .ldvlfda.dlsdivep...lvlilsaesrgv.mviPlentlerfyvqvearaekeer...sekfteeevkarlreivgektldv.eieevsawtv 273
                      ++l d+   +++ ++   + +i++++  +  +++  e+  + ++ + ++ + +e++    +  + +e+++ ++e+++++   + +  + ++   
     EEA21418.1 192 kGEILKDVpACQEYLKQdcvNIWIGEDKHLVQnTLRDGEE-FNWIITHKDTADIQESWfqpGNMDDVRELVQGWDESIASAVRATpSCLDWKICYR 286
                    1356666666666666699999999988887433333333.5545555556666666654333334456677777766655444425555555444 PP

                    EEEEESSSEETTEEE-GGGTEEE-STTSHHHHHHHHHHH..HHHHHHH CS
  FAD_binding_3 274 aqrvaekyrkgrvflaGDAaHihpPtgGqGlNtaiqDav..nLawkLa 319
                    a   +   ++ ++ l GD++H h Pt +qG   a + +    L+ kLa
     EEA21418.1 287 APLPTWVSKSSKIALLGDSCHPHLPTSAQGASQATESSAvlALCMKLA 334
                    44444445556*******************998887655114444444 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   9.5e-07    0.0012       2      36 ..      16      50 ..       9      68 .. 0.81
   2 !   12.9   0.0   3.6e-05     0.046     191     240 ..     120     167 ..     112     179 .. 0.89

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 9.5e-07
                 SEEEE--SHHHHHHHHHHHHHTS-EEEEETTHCHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  2 dvvviGgGpAGlaaaltlaqagakvtlvelegtcl 36
                 +v+++G+G +Gla+a+ +  ag++v+++e+ +++l
   EEA21418.1 16 RVIIVGAGLGGLACAMAMHYAGFEVIVFEKVREFL 50
                 78899999999999999999999998887555554 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 3.6e-05
                  HHHHHTTEEEEESCEEEEEEETTEEEEEEETTSCEEEESEEEE-S-EEES CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 191 ealekeGvevklgtsvkeidgngeklevvledgeeidadlvvvavGvrps 240
                  +++++ G+ + +g++++ +d++    +v+l+dg+++ adl+v a G++ +
   EEA21418.1 120 NRVKQLGIPINMGHEIVSFDEDAP--SVTLKDGRTFYADLIVGADGIKSR 167
                  678899**************9998..89****************999876 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.9   0.3   4.7e-10     6e-07       2      33 ..      17      48 ..      16      50 .. 0.95

  Alignments for each domain:
  == domain 1  score: 28.9 bits;  conditional E-value: 4.7e-10
                   EEEE--SHHHHHHHHHHHHTTT-EEEEESSSG CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGlkvavvekeqe 33
                   vi++G+Gl+GLa+A++++ aG +v+v ek+ e
     EEA21418.1 17 VIIVGAGLGGLACAMAMHYAGFEVIVFEKVRE 48
                   9****************************876 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.3     5e-07   0.00064       2      37 ..      16      51 ..      15      59 .. 0.94
   2 ?    3.8   0.0     0.014        18     114     167 ..     117     167 ..     115     170 .. 0.86

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 5e-07
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SSSSS-H CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVlllekakklgr 37
                 +vi++G+G  Gl +A++++ +g +V+++ek ++++r
   EEA21418.1 16 RVIIVGAGLGGLACAMAMHYAGFEVIVFEKVREFLR 51
                 79****************************998876 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.014
                  HHHHHHHHHT-EEE-S--EEEEECETTE.EEEEE.TTEEEEESEEEE----SS- CS
  HI0933_like 114 allkelkeagvklrletevksvekeedgkfrvktkseeeleadklvlAtGGlSi 167
                  a+++++k+ g+ +++ +e+ s+++++    +v++k+++++ ad +v A G +S 
   EEA21418.1 117 AFINRVKQLGIPINMGHEIVSFDEDA---PSVTLKDGRTFYADLIVGADGIKSR 167
                  57899*****************5544...5588999**********99998885 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.3   2.4e-08   3.1e-05       1      28 [.      19      46 ..      19      49 .. 0.95

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 2.4e-08
                   EE--SHHHHHHHHHHHCCTEEEEEE-SS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekr 28
                   IvGaGl+Gl++A +++ agf+v ++ek 
     EEA21418.1 19 IVGAGLGGLACAMAMHYAGFEVIVFEKV 46
                   9*************************95 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.3   3.5e-06    0.0045       2     147 ..      17     161 ..      16     179 .. 0.59

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 3.5e-06
                 EEEE-SSHHHHHHHHHHHHTT--EEEEES-GGGTT--SSSSEEE-TTHHHHHHHHHHHT-SHHHHHHHHEEEEEEESTTS-..CCC-EEEEEE-HHHHH CS
        GIDA   2 viViGgGhAGceAAlaaarlGakvlLithkldtiaelsCnpsiggiakgllvrEidalggliikaadkagiqfrilNrskG..pavralraqvdrelys 98 
                 vi++G+G+ G+++A+a+  +G++v+ + +k+ ++++l+ +  +g +a  ll+r    l+ ++i + +k+ + ++i     G   a + l   +d   y 
  EEA21418.1  17 VIIVGAGLGGLACAMAMHYAGFEVIVF-EKVREFLRLGDSLGLGENALKLLKR--WGLYEELIAIGNKNPV-MNIRRWDDGkiMATQPL---MDMAGYI 108
                 9************************99.8888888886555555455555444..2344444444444444.22222222200222222...4444443 PP

                 ....HHHHHHHHTSTTEEEEES-EEEEEECTTEEEEEEETTS-EEEECEEEE- CS
        GIDA  99 ....kevteklenepnleiieeeveeliveekkvkgvvtedgetikakavvia 147
                      +  + +++ ++l i  ++ +e++  ++    v+++dg+t+ a+ +v a
  EEA21418.1 109 ghrgDYHVAFINRVKQLGIPINMGHEIVSFDEDAPSVTLKDGRTFYADLIVGA 161
                 11112223345555556666666666666666666666666666666666655 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   0.6   0.00011      0.14       1      37 [.      16      52 ..      16      62 .. 0.92
   2 ?    2.4   0.0      0.18   2.3e+02      47      80 ..     119     149 ..     113     150 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 0.00011
                EEEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSSTT CS
   Pyr_redox  1 kvvvvGgGyiglElAgalaelgkkVtvversdkllrl 37
                +v++vG+G+ gl +A a++  g +V v+e   ++lrl
  EEA21418.1 16 RVIIVGAGLGGLACAMAMHYAGFEVIVFEKVREFLRL 52
                79***************************99999965 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.18
                 HHHHHHTTEEEECSEEEEEEEEETTSEEEEEEET CS
   Pyr_redox  47 qeklekngievllntkveeiegsedgvesvklkd 80 
                  ++++++gi + ++++++++++++     v+lkd
  EEA21418.1 119 INRVKQLGIPINMGHEIVSFDEDAPS---VTLKD 149
                 578999***************88875...88876 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.3   5.7e-05     0.074       1      30 [.      16      47 ..      16      55 .. 0.91
   2 ?    0.0   0.0      0.38   4.9e+02     141     206 ..     106     170 ..      72     205 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 5.7e-05
                EEEEECTSHHHHHHHHHHHHTT..EEEEESSS CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..Vtllekgd 30
                +v+i+G+G  Gl++A++   +g  V+++ek +
  EEA21418.1 16 RVIIVGAGLGGLACAMAMHYAGfeVIVFEKVR 47
                59****************9899*******965 PP

  == domain 2  score: 0.0 bits;  conditional E-value: 0.38
                 EEE.EHHHHHHHHHHHHHHTT-EEEESECEEEEEEEETCEEEEEEECT.EEEEEEEEEEE--GGGHH..H CS
         DAO 141 gqv.dpakltaalaraaealGveilegtevtgleeedgkvwgverttp.gendaadavVnaaGawsd..l 206
                 g + +   +  a+ +++++lG+ i  g+e+++++e+   +  v  t + g+++ ad +V a G+ s+  +
  EEA21418.1 106 GYIgHRGDYHVAFINRVKQLGIPINMGHEIVSFDED---APSV--TLKdGRTFYADLIVGADGIKSRarE 170
                 566677888889999999999999999999999664...5555..3343877556889999998876432 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.4   1.5e-05     0.019       1      29 [.      18      45 ..      18      50 .. 0.94

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 1.5e-05
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEk 29
                 iI+GaG  Gla+a+++  ag+ ++++ Ek
   EEA21418.1 18 IIVGAGLGGLACAMAMHYAGF-EVIVFEK 45
                 8********************.6999998 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.1   3.5e-05     0.045      18      49 ..      15      45 ..      10      63 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 3.5e-05
                EEEEEE--SHHHHHHHHHHHHCTTS-EEEEES CS
        Thi4 18 sDvvivGaGssGLtaayylakkpdlkvailer 49
                + v+ivGaG  GL++a  +  + +++v+++e+
  EEA21418.1 15 TRVIIVGAGLGGLACAMAMHYA-GFEVIVFEK 45
                569***************9999.*******97 PP

>> DUF1344  Protein of unknown function (DUF1344)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00049      0.63       8      38 ..     135     165 ..     131     172 .. 0.84
   2 ?   -3.7   0.0       9.4   1.2e+04      19      26 ..     225     232 ..     225     233 .. 0.84
   3 ?   -2.4   0.0       3.6   4.6e+03       3      18 ..     439     454 ..     438     455 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00049
     DUF1344   8 IkkidkkalsitLdDGktYklpeefdidgLk 38 
                 I + d +a s+tL DG t+ +   + +dg+k
  EEA21418.1 135 IVSFDEDAPSVTLKDGRTFYADLIVGADGIK 165
                 8999***************887776666666 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 9.4
     DUF1344  19 tLdDGktY 26 
                 tL DG+++
  EEA21418.1 225 TLRDGEEF 232
                 899**987 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 3.6
     DUF1344   3 dvegtIkkidkkalsi 18 
                 d+ g++k++ + + s+
  EEA21418.1 439 DAYGKVKDVPPSQSSL 454
                 789******9999987 PP

>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   0.0     0.002       2.5       1      22 [.      24      45 ..      24      48 .. 0.93
   2 ?   -0.3   0.0      0.39     5e+02     234     257 ..     136     159 ..     116     166 .. 0.80
   3 ?   -0.3   0.0       0.4   5.2e+02     377     446 ..     253     323 ..     241     329 .. 0.77

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.002
                   HHHHHHHHHHHHTTEEEEEEES CS
  Amino_oxidase  1 laGLaaArqLlsaGfdVtvlEa 22
                   l GLa+A  ++ aGf+V+v+E 
     EEA21418.1 24 LGGLACAMAMHYAGFEVIVFEK 45
                   57*******************5 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.39
                    EEEETTCEEEEETTSTEEEESEEE CS
  Amino_oxidase 234 ikregdgvtvtledgevveaDaVv 257
                    ++ ++d  +vtl+dg+++ aD +v
     EEA21418.1 136 VSFDEDAPSVTLKDGRTFYADLIV 159
                    556889999************987 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.4
                    SSTCSEEEEEECCTETTTSSSEEE.BTTHHHHHHHHHHCH......HCSTTEEE.SGGGCTTTTTSHHHHHHHHHH CS
  Amino_oxidase 377 vpepkatlvtrWhtdplargsysyvsvgpghedydplakp......egdprlffAGehtsreypgtvegAilSGlr 446
                    + ++++ lv  W  +++a    s+v+++p+ +d+   ++        + + + + G++++ ++p + +gA ++  +
     EEA21418.1 253 NMDDVRELVQGWD-ESIA----SAVRATPSCLDWKICYRAplptwvSKSSKIALLGDSCHPHLPTSAQGASQATES 323
                    5566777888887.8888....888999999999999999566666666699999*****9999999999776555 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   0.00028      0.36      28      75 ..      14      63 ..       7      89 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00028
                 --EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHHHHHHHHH..TTTCEC CS
  AlaDh_PNT_C 28 pakvlviGgGvaGlqAiatakglgakVtvlDvrparleqles..lgakfv 75
                   +v+++G+G  Gl+ + + +  g +V v+++  + l+  +s  lg++ +
   EEA21418.1 14 TTRVIIVGAGLGGLACAMAMHYAGFEVIVFEKVREFLRLGDSlgLGENAL 63
                 679****************************9999888888755555555 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.2   0.00031       0.4       2      30 ..      17      45 ..      16      50 .. 0.93

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00031
  FAD_oxidored  2 vvVvGGgpaGvaAAiaAaraGakvlLvee 30
                  v++vG+g++G+a+A+a   aG +v++ e+
    EEA21418.1 17 VIIVGAGLGGLACAMAMHYAGFEVIVFEK 45
                  9************************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (461 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       431  (0.0240393); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.41
# Mc/sec: 3345.47
//
Query:       EEA21419.1  [L=690]
Description: nitrogen assimilation transcription factor nit-4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.2e-32  112.2   2.0    2.4e-32  112.0   0.0    2.0  2  Fungal_trans  Fungal specific transcription factor domain
    0.00015   21.8  10.3    0.00037   20.5  10.3    1.7  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.0   0.0   2.7e-36   2.4e-32       1     204 [.     241     446 ..     241     485 .. 0.86
   2 ?   -1.8   0.4      0.14   1.2e+03      14      66 ..     516     566 ..     505     617 .. 0.61

  Alignments for each domain:
  == domain 1  score: 112.0 bits;  conditional E-value: 2.7e-36
  Fungal_trans   1 ldrffsnfhpqfpilhkpsflpkt...........ssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfss 86 
                   ld +++ +hp+fp++h+++fl +            +s+ +   +  ++ lll+++al a+f+++ +++++s+  +e      + ++ae+l+   ++ 
    EEA21419.1 241 LDAYWTFVHPCFPVVHRETFLFQLskdrrgmprqgRSAFDQLERRIPQVLLLSMFALSARFVDNCESREDSDPGDE------YAIKAETLL---AQH 328
                   789*******************************99999999***************************7777774......456******...777 PP

  Fungal_trans  87 pssslwilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkks.lwklweeeaesrrRlwwaaFylDktialklGrppllddsqin 182
                     ss++ + +L ++++ e++++  +  + ++g a+r+a++lgLhr+ps ++k++ + + +  e ++rr +ww+aF+lD++i+   Grp  ++d++ +
    EEA21419.1 329 KQSSINCCLALIMMAYREIGTGG-SISWIYVGKAIRMAQDLGLHRDPSIWKKTQcFRNISSVEMQIRRLIWWGAFVLDRYISAWQGRPCAIHDDDFD 424
                   777799999*************7.999************************999988888888**************************89****** PP

  Fungal_trans 183 lpLPcddddlwesddaseetlv 204
                   ++LP+d  +++   + s++ +v
    EEA21419.1 425 TQLPDDTLHENRDHSLSCFIQV 446
                   ****887766555555555444 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.14
  Fungal_trans  14 ilhkpsflpktssenssksayasplll...lailalGalfsesetkesnssltses 66 
                   +lh+p f ++t    ++++++++p ll    a +a++ l+ + +++++ + +    
    EEA21419.1 516 LLHRP-FIVTT----PNETQSNNPSLLaatSAAVAIANLLEHFTSSYNPTFAPPFF 566
                   67776.44555....56677777777767777888888888888877766666543 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5  10.3   4.2e-08   0.00037       1      39 [.      30      70 ..      30      71 .. 0.86

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 4.2e-08
                SS-HHHHHCT---STSSSS..-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus  1 haCdnCrkkKvKCdakkPa..CsnCkklnleCtfysesskr 39
                +aCdnC+k K+KC  + ++  C nC+ l   Ctf++  +kr
  EEA21419.1 30 RACDNCSKSKSKCLLRPGTktCENCRFLDIACTFNRTVKKR 70
                69************9555555************99887776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (690 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       525  (0.0292822); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.43
# Mc/sec: 4861.94
//
Query:       EEA21420.1  [L=151]
Description: 40S ribosomal protein S13 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.9e-29  101.5   0.1    3.1e-29  100.8   0.1    1.4  1  Ribosomal_S13_N  Ribosomal S13/S15 N-terminal domain
    2.6e-14   53.2   0.1    3.8e-14   52.7   0.1    1.2  1  Ribosomal_S15    Ribosomal protein S15
  ------ inclusion threshold ------
      0.017   15.0   0.1      0.042   13.8   0.0    1.6  2  PAX              'Paired box' domain


Domain annotation for each model (and alignments):
>> Ribosomal_S13_N  Ribosomal S13/S15 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.8   0.1   5.2e-33   3.1e-29       1      60 []       1      60 [.       1      60 [. 1.00

  Alignments for each domain:
  == domain 1  score: 100.8 bits;  conditional E-value: 5.2e-33
                     X--SSSSSS--------S-SS--TTS---HHHHHHHHHHHHHTT--HHHHHHHHHHCCT- CS
  Ribosomal_S13_N  1 MarmhsrgkGkSgSarPyrreapsWlklskeeveelivklakkGltpSqIGviLRDqyGv 60
                     M+r+hs+gkG++ Sa Py+r++p+Wlk+++++v+++i+klakkG tpSqIGv+LRD++G+
       EEA21420.1  1 MGRLHSKGKGIAASAIPYSRTPPAWLKTTPDQVTDQICKLAKKGATPSQIGVVLRDSHGI 60
                     ***********************************************************9 PP

>> Ribosomal_S15  Ribosomal protein S15
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.7   0.1   6.3e-18   3.8e-14       4      78 ..      74     146 ..      70     148 .. 0.93

  Alignments for each domain:
  == domain 1  score: 52.7 bits;  conditional E-value: 6.3e-18
                    HHHHHSSSTT-TSSHHHHHHHHHHHHHHHHHHHHCTTT-HHHHHHHHHHHHHHHHHHHHHHHH-H..HHHHHHHHHC CS
  Ribosomal_S15   4 likefqrhekDtGspevqiallterInnltehlkenkkDkhsrrgLlklvskRrkllkYLkrkdv..erYkkliekl 78 
                    ++k+++ ++    ++++++++l+++++++++hl++n+kDk+ + +L++++s++++l +Y+k+  v  +++++  +++
     EEA21420.1  74 ILKSNGLAP----EIPEDLYFLIKKAVSVRKHLERNRKDKDGKFRLILIESRIHRLSRYYKTVGVlpPTWRYESATA 146
                    588899999....9**************************************************9999999988776 PP

>> PAX  'Paired box' domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0     7e-06     0.042      18      50 ..      29      61 ..      26      79 .. 0.91
   2 ?   -2.7   0.0      0.87   5.2e+03      54      65 ..     125     136 ..     119     138 .. 0.72

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 7e-06
         PAX 18 lpdsirqkivelahsgvrpcvisrqlrvshgcv 50
                 pd++  +i +la++g+ p +i   lr shg  
  EEA21420.1 29 TPDQVTDQICKLAKKGATPSQIGVVLRDSHGIA 61
                69****************************974 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 0.87
         PAX  54 lgryqetgsirp 65 
                 l+ry++t  + p
  EEA21420.1 125 LSRYYKTVGVLP 136
                 789999876655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (151 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       462  (0.0257683); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.41u 0.28s 00:00:00.69 Elapsed: 00:00:00.43
# Mc/sec: 1056.99
//
Query:       EEA21421.1  [L=825]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-24   86.4   0.1    4.6e-24   84.6   0.0    2.0  2  VRR_NUC   VRR-NUC domain
  ------ inclusion threshold ------
       0.16   11.9   1.4       0.38   10.7   1.4    1.7  1  Rho_N     Rho termination factor, N-terminal domain


Domain annotation for each model (and alignments):
>> VRR_NUC  VRR-NUC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       1.1   9.9e+03      15      44 ..     502     526 ..     497     535 .. 0.69
   2 !   84.6   0.0   5.1e-28   4.6e-24      16     106 ..     722     817 ..     705     819 .. 0.90

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 1.1
                 HHTTCBBTTB-TTTSSHHCHHHHHHHHHHH CS
     VRR_NUC  15 eklgllapvvnwgelsqcepkealaklfra 44 
                 e+++l+a ++++g++     +ea++k+ ++
  EEA21421.1 502 EEHYLWALTPSEGRA-----DEAQKKYWKR 526
                 577888999999985.....5556665555 PP

  == domain 2  score: 84.6 bits;  conditional E-value: 5.1e-28
                 HTTCBBTTB-TTTSS.......HHCHHHHHHHHHHHHHHCHHHHSSTS-SEEEEETTTTE..EEEEEEE-TT----HHHHHHHHHHHHTT-EEEEEEE CS
     VRR_NUC  16 klgllapvvnwgels.......qcepkealaklfralledyrglrsGvPDLilwieeqkryvflliEvKgpgdrlsdnQrkwldelarsgvrvevcrv 106
                  ++++  +v+w  ++       qc+ ++ala +++ ++++y+++++G+PDL+lw++ +k+  +++ EvK+++drlsd+Qr w++ l+  gv+ve+c+ 
  EEA21421.1 722 SKQTSIVGVDWTYALddlveivQCFSGTALATVCKVMAQEYQQRGGGIPDLFLWNPDKKE--VMFAEVKSENDRLSDTQRLWIHVLMGAGVNVELCNA 817
                 334689999999999********************************************9..**********************************96 PP

>> Rho_N  Rho termination factor, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   1.4   4.2e-05      0.38       7      36 ..     260     286 ..     258     293 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 4.2e-05
                 HHHHHHHHHHTT-TTGGGS-HHHHHHHHHH CS
       Rho_N   7 lseLraiAkelgienysrlRKqdLIfaIlk 36 
                 l eL+++Ake ++   ++  K++L+ a+l+
  EEA21421.1 260 LDELKEMAKEAKV---QGKNKKELVAALLQ 286
                 78***********...889*********98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (825 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       804  (0.0448435); expected 358.6 (0.02)
Passed bias filter:                      516  (0.0287802); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.66u 0.29s 00:00:00.95 Elapsed: 00:00:00.44
# Mc/sec: 5631.21
//
Query:       EEA21422.1  [L=93]
Description: COMPASS complex subunit Sdc1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-15   57.1   0.2    1.4e-15   56.7   0.2    1.2  1  Dpy-30    Dpy-30 motif


Domain annotation for each model (and alignments):
>> Dpy-30  Dpy-30 motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.7   0.2   7.8e-20   1.4e-15       1      42 []      42      83 ..      42      83 .. 0.96

  Alignments for each domain:
  == domain 1  score: 56.7 bits;  conditional E-value: 7.8e-20
                -HHHHHHHHTHHHHHHHHHHHHHH--SSHHHHHHHHHHHHGG CS
      Dpy-30  1 parkYLnktvaPiLlqGLtelAkeRPeDPieyLAeYLlknkn 42
                par YLn++++P Ll+GL+ +A+e+P++P+++L+eYL+k++n
  EEA21422.1 42 PARIYLNEKITPYLLEGLKDIAREQPQNPLKVLGEYLIKKSN 83
                7899***********************************875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (93 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       222  (0.0123822); expected 358.6 (0.02)
Passed bias filter:                      197  (0.0109878); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.35u 0.26s 00:00:00.61 Elapsed: 00:00:00.41
# Mc/sec: 683.40
//
Query:       EEA21423.1  [L=341]
Description: transformer-SR ribonucleoprotein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-19   69.4   0.0    2.5e-19   68.9   0.0    1.2  1  RRM_1     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom
     0.0043   16.6   0.0     0.0063   16.1   0.0    1.2  1  RRM_5     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.9   0.0   2.8e-23   2.5e-19       1      69 [.      72     141 ..      72     142 .. 0.98

  Alignments for each domain:
  == domain 1  score: 68.9 bits;  conditional E-value: 2.8e-23
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrel 69 
                 lfV++++p +te ++++lF+k+G++++++++ d  t+ s+gf+fV++ + e+A++A+e l+g+ ++g +l
  EEA21423.1  72 LFVTGIHPRLTEADISRLFEKYGDVENCSIMLDpHTKESRGFGFVKMVTAEQADAAKEGLQGEVIDGLTL 141
                 8*****************************************************************9887 PP

>> RRM_5  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0   7.1e-07    0.0063      22      97 ..      65     144 ..      46     155 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 7.1e-07
       RRM_5  22 gvaegsVllVyglepdkvnldklFnlfclYgnvervkfl.....ktkketalvqmgdasaveravqHLnnaklfgkrleva 97 
                  v+ gs l+V+g++p  ++   +  lf  Yg+ve   ++     k  ++  +v+m  a +++ a + L+++ + g  l + 
  EEA21423.1  65 AVNPGSNLFVTGIHPR-LTEADISRLFEKYGDVENCSIMldphtKESRGFGFVKMVTAEQADAAKEGLQGEVIDGLTLSIE 144
                 45678999*****985.6667799***************6663344557899******************99988877775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (341 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       264  (0.0147247); expected 358.6 (0.02)
Passed bias filter:                      138  (0.00769703); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 2446.33
//
Query:       EEA21424.1  [L=1141]
Description: PHD finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-32  113.2   0.0    2.9e-32  112.2   0.0    1.6  1  EPL1          Enhancer of polycomb-like
    1.6e-31  108.7   7.9    1.6e-31  108.7   7.9    2.3  2  zf-HC5HC2H_2  PHD-zinc-finger like domain
    2.8e-26   91.6   5.4    2.8e-26   91.6   5.4    2.8  3  zf-HC5HC2H    PHD-like zinc-binding domain
    1.7e-14   53.1   9.4    7.7e-14   51.0   3.4    2.6  2  PHD_2         PHD-finger
      4e-10   39.4  20.3    8.8e-09   35.1  10.0    2.6  2  PHD           PHD-finger
  ------ inclusion threshold ------
      0.013   15.7   3.5      0.013   15.7   3.5    2.6  2  zf-RING-like  RING-like domain
      0.091   12.4   8.4      0.016   14.8   2.2    2.4  2  zf-PHD-like   PHD/FYVE-zinc-finger like domain


Domain annotation for each model (and alignments):
>> EPL1  Enhancer of polycomb-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.2   0.0   1.1e-35   2.9e-32       1     157 []     142     365 ..     142     365 .. 0.79

  Alignments for each domain:
  == domain 1  score: 112.2 bits;  conditional E-value: 1.1e-35
        EPL1   1 rqprldikkkLkviseeevdgldeseseeeiseknsnkensqqavetgvdkkeen.................ekhqviaaakkkesssasske...... 76 
                 ++p+ldi++k++v+s+eevdg ++   ++ i+++++++  s   +++g d+++                   +                   +      
  EEA21424.1 142 FHPDLDIEAKFAVFSAEEVDGANKP--QQPITNNQLTNGVS--MTSHGDDASTIAtpaipqtppkrrpgrppR-------------------Rpdamls 217
                 79*******************9854..33444444443333..223333332222222222222222223330...................1455666 PP

        EPL1  77 ...............slkkeelkLpkPsfre................................ferppssyirfseks.eeeldd.............. 113
                                 +++e+l+LpkP+f+                                 f r+++++ir+ e   ee+ld               
  EEA21424.1 218 aiispeqpkvvpppgPNPRERLTLPKPNFHLrdpfvryeqkgvnqqnyvdrtmasvgyqesdlFVRHDRRLIRMAEGAiEEDLDLdppvtdgdtnaaig 316
                 66666666666667779**********9999999999999*****************9999999999****************99************** PP

        EPL1 114 .....eveYdMDEeDekWLeelnekrkkegvekisediFEivmdrlEke 157
                      +veYdMDE+DekWLe++n++rk++++e+i++++FEi+m+++Eke
  EEA21424.1 317 slgvgRVEYDMDEQDEKWLEDYNNRRKADQLEAIKPAVFEITMTKIEKE 365
                 ************************************************8 PP

>> zf-HC5HC2H_2  PHD-zinc-finger like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   1.6      0.12   3.1e+02      53      84 ..     404     437 ..     388     440 .. 0.84
   2 !  108.7   7.9   6.2e-35   1.6e-31       2     110 .]     462     576 ..     461     576 .. 0.95

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.12
  zf-HC5HC2H_2  53 rlkekCllCkkr....kGaciqCskkeCktafHvtC 84 
                   +  +kC++C++     + a + C    C+ a H  C
    EEA21424.1 404 EQDSKCAVCDDGdcenSNAIVFCDG--CDLAVHQEC 437
                   46789****9977776778888887..******999 PP

  == domain 2  score: 108.7 bits;  conditional E-value: 6.2e-35
  zf-HC5HC2H_2   2 eCvlCkkkgGalkktsderwvHvlCallvpevsfsnvaerepvd.vekikkerlkekCllCkkrkGaciqCskkeCktafHvtCalaaglvmeledl 97 
                   +C++C++++Ga+k+t++++w H+lC +++pev + n++ +epv+ vek++k+r+k++C++Ck+r+Ga+iqCs+k+C  afHvtCa++++l++++++ 
    EEA21424.1 462 NCIFCPNTEGAFKQTNTSKWSHLLCSIWIPEVGIGNQSLMEPVTdVEKVPKSRWKLQCYICKQRMGASIQCSNKNCFVAFHVTCARRSQLYLKMKSA 558
                   7******************************************99**************************************************99 PP

  zf-HC5HC2H_2  98 ek.....klkvialckkh 110
                   ++     +   +a+c+kh
    EEA21424.1 559 HNsaimdSHLLKAFCHKH 576
                   887777666677888887 PP

>> zf-HC5HC2H  PHD-like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   1.2     0.021        53      33      65 ..     403     437 ..     389     441 .. 0.86
   2 ?   -2.5   0.0       2.4   6.3e+03      38      51 ..     462     475 ..     456     479 .. 0.80
   3 !   91.6   5.4   1.1e-29   2.8e-26       1      89 [.     483     576 ..     483     577 .. 0.90

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.021
  zf-HC5HC2H  33 erkklkCylCk....kkvGaciqCskkkCkkafHvtC 65 
                 e+++ kC +C+    ++  a++ C+   C  a H  C
  EEA21424.1 403 EEQDSKCAVCDdgdcENSNAIVFCDG--CDLAVHQEC 437
                 567889****977765689*****98..********9 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 2.4
  zf-HC5HC2H  38 kCylCkkkvGaciq 51 
                 +C++C ++ Ga  q
  EEA21424.1 462 NCIFCPNTEGAFKQ 475
                 7****999999765 PP

  == domain 3  score: 91.6 bits;  conditional E-value: 1.1e-29
  zf-HC5HC2H   1 HvvCalwipevvfeeekeiemeeiedvekikkerkklkCylCkkkvGaciqCskkkCkkafHvtCakeagllleee.......eekeklksyCkkH 89 
                 H++C +wipev + +++   me+++dvek++k+r+kl+Cy+Ck+++Ga+iqCs+k+C  afHvtCa++++l+l+++        +++ lk++C+kH
  EEA21424.1 483 HLLCSIWIPEVGIGNQS--LMEPVTDVEKVPKSRWKLQCYICKQRMGASIQCSNKNCFVAFHVTCARRSQLYLKMKsahnsaiMDSHLLKAFCHKH 576
                 99*********998766..4******************************************************99554444444459******** PP

>> PHD_2  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.0   3.4     3e-17   7.7e-14       2      35 ..     421     453 ..     420     454 .. 0.96
   2 !    5.0   0.4    0.0068        17       5      20 ..     530     547 ..     527     551 .. 0.86

  Alignments for each domain:
  == domain 1  score: 51.0 bits;  conditional E-value: 3e-17
       PHD_2   2 npllsCdkCsvaVHasCYGvskesdgeeWlCrrC 35 
                 n +++Cd+C +aVH++CYGv+++++g +WlCr+C
  EEA21424.1 421 NAIVFCDGCDLAVHQECYGVPYIPEG-QWLCRKC 453
                 89************************.******* PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.0068
       PHD_2   5 lsCd..kCsvaVHasCYG 20 
                 ++C+  +C va+H  C +
  EEA21424.1 530 IQCSnkNCFVAFHVTCAR 547
                 7899889*********76 PP

>> PHD  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.1  10.0   3.4e-12   8.8e-09       2      50 ..     409     454 ..     408     455 .. 0.94
   2 !    9.3   2.6   0.00041       1.1       2      32 ..     519     548 ..     518     558 .. 0.84

  Alignments for each domain:
  == domain 1  score: 35.1 bits;  conditional E-value: 3.4e-12
                 BTTTTS.TTSTTSCEEEETTTSCEEETTTSSSTHSHHSHHSSTBSSTTTH CS
         PHD   2 CavCkk.ksdeeeelvqCdgCkrwfHqkClkppleseekpegewlCekCk 50 
                 CavC++ + ++++ +v+CdgC+ ++Hq+C+++p     +peg+wlC+kC+
  EEA21424.1 409 CAVCDDgDCENSNAIVFCDGCDLAVHQECYGVP----YIPEGQWLCRKCQ 454
                 ******99999**********************....559999******7 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.00041
                 BTTTTSTTSTTSCEEEET..TTSCEEETTTSSS CS
         PHD   2 CavCkkksdeeeelvqCd..gCkrwfHqkClkp 32 
                 C +Ck+     +  +qC   +C  +fH++C + 
  EEA21424.1 519 CYICKQ---RMGASIQCSnkNCFVAFHVTCARR 548
                 9*****...699*****6337*********865 PP

>> zf-RING-like  RING-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   7.5       2.4   6.1e+03      12      43 .]     424     453 ..     408     453 .. 0.74
   2 ?   15.7   3.5   5.3e-06     0.013       1      30 [.     519     548 ..     519     556 .. 0.95

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 2.4
  zf-RING-like  12 vrCsnesCnvrlHvdCfqhyirthsskkCpkC 43 
                   v C    C  ++H++C+   +  + +  C kC
    EEA21424.1 424 VFCD--GCDLAVHQECYGVPYIPEGQWLCRKC 453
                   4577..888*******9765546777777777 PP

  == domain 2  score: 15.7 bits;  conditional E-value: 5.3e-06
  zf-RING-like   1 CeaCkeivtqGvrCsnesCnvrlHvdCfqh 30 
                   C +Ck+ +   ++Csn++C v++Hv C+++
    EEA21424.1 519 CYICKQRMGASIQCSNKNCFVAFHVTCARR 548
                   99*************************986 PP

>> zf-PHD-like  PHD/FYVE-zinc-finger like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.8   2.2   6.3e-06     0.016       1      31 [.     409     439 ..     409     444 .. 0.95
   2 ?    0.3   0.5      0.18   4.6e+02      40      59 ..     507     526 ..     485     568 .. 0.65

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 6.3e-06
  zf-PHD-like   1 CdtCaeskdeekgqlvyCqGCslsyhkaClG 31 
                  C++C   + e+  ++v+C GC l+ h++C G
   EEA21424.1 409 CAVCDDGDCENSNAIVFCDGCDLAVHQECYG 439
                  99******9999*****************98 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.18
  zf-PHD-like  40 vtkvgedsFvlqCrrCigla 59 
                  v kv + ++ lqC  C + +
   EEA21424.1 507 VEKVPKSRWKLQCYICKQRM 526
                  56777777777777775443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1141 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       594  (0.0331307); expected 358.6 (0.02)
Passed bias filter:                      389  (0.0216967); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.77u 0.25s 00:00:01.02 Elapsed: 00:00:00.43
# Mc/sec: 7938.53
//
Query:       EEA21425.1  [L=180]
Description: hypothetical protein PMAA_052330 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.3e-07   30.1   3.5    6.6e-07   29.5   0.5    2.3  2  Myb_DNA-bind_6   Myb-like DNA-binding domain
      0.006   16.7   1.9      0.011   15.9   0.1    2.3  2  Myb_DNA-binding  Myb-like DNA-binding domain
  ------ inclusion threshold ------
      0.051   13.8   0.7       0.24   11.7   0.1    2.2  2  APOC4            Apolipoprotein C4
       0.27   11.6   5.0         10    6.6   1.1    2.7  3  MADF_DNA_bdg     Alcohol dehydrogenase transcription factor M


Domain annotation for each model (and alignments):
>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.5   0.5   1.5e-10   6.6e-07       1      59 [.      38      95 ..      38      96 .. 0.80
   2 ?    1.8   0.2     0.067     3e+02      13      38 ..     100     129 ..      93     170 .. 0.67

  Alignments for each domain:
  == domain 1  score: 29.5 bits;  conditional E-value: 1.5e-10
  Myb_DNA-bind_6  1 WteeEdeiLlklvekygndWknIaea.l.nrRtpkqcfdrwknkLrpkisrkkwskeedir 59
                    W+  +d  L++   + g+ W++I+++ + n +t+++c+ r+++ L +k++ ++w++e  ++
      EEA21425.1 38 WSYHDDTVLINAR-ARGQGWSQIQKEhFlN-KTANACRKRHER-LVAKRRGTEWNQEMLEK 95
                    6666666666654.45899****9985336.************.************97655 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.067
  Myb_DNA-bind_6  13 veky.gndWknIaealn...rRtpkqcfdr 38 
                     ++++ ++ W + a+a++   +   k cf+r
      EEA21425.1 100 YSRCrEQIWQPLANAIGekwQDVEKICFER 129
                     444433468888888874444444556665 PP

>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.1   2.5e-06     0.011       2      41 ..      36      75 ..      35      80 .. 0.88
   2 ?   -0.3   0.2      0.27   1.2e+03      17      17 ..     113     113 ..      78     133 .. 0.63

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 2.5e-06
                     SSSBHHHHHHHHHHHHHHTTCHHHH.HHHHTSS-HHHHHHH CS
  Myb_DNA-binding  2 gkWteeEdelLleavkkhGnrWkkI.aerlggRtekqcrsr 41
                     ++W+  +d  L++a ++ G  W+ I  e++ ++t+++cr r
       EEA21425.1 36 SNWSYHDDTVLINARAR-GQGWSQIqKEHFLNKTANACRKR 75
                     58***************.555****666888********98 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.27
                      H CS
  Myb_DNA-binding  17 k 17 
                      +
       EEA21425.1 113 N 113
                      1 PP

>> APOC4  Apolipoprotein C4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.1   5.3e-05      0.24      55      88 ..      40      74 ..      31      84 .. 0.86
   2 ?    0.3   0.1       0.2   8.8e+02      22      40 ..     101     120 ..      80     139 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 5.3e-05
       APOC4 55 yyddh.lkdlgprtkawlrsskdsllnkakslcPr 88
                y+dd  l + ++r + w +  k+++lnk+ + c +
  EEA21425.1 40 YHDDTvLINARARGQGWSQIQKEHFLNKTANACRK 74
                6666536788999******************9975 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.2
       APOC4  22 skvke.lveplvtrtrerwq 40 
                 s+ +e + +pl +   e+wq
  EEA21425.1 101 SRCREqIWQPLANAIGEKWQ 120
                 34443134688888888887 PP

>> MADF_DNA_bdg  Alcohol dehydrogenase transcription factor Myb/SANT-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0      0.29   1.3e+03      64      81 ..      25      43 ..      13      47 .. 0.72
   2 ?    6.6   1.1    0.0022        10      21      53 ..      48      80 ..      38     101 .. 0.81
   3 ?    5.9   0.2    0.0037        16      22      60 ..     101     146 ..      88     171 .. 0.64

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.29
  MADF_DNA_bdg 64 k.sseskekkkskwryfee 81
                  +  +es+++++s+w+y ++
    EEA21425.1 25 RsLNESGTNHASNWSYHDD 43
                  1456899999999999875 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0022
  MADF_DNA_bdg 21 nkekrekaweeiaeelnekvdveeckkkwknLR 53
                  n  +r + w++i +e   + ++++c+k+ + L 
    EEA21425.1 48 NARARGQGWSQIQKEHFLNKTANACRKRHERLV 80
                  677899*********966688889***988775 PP

  == domain 3  score: 5.9 bits;  conditional E-value: 0.0037
  MADF_DNA_bdg  22 kekrekaweeiaeelnekvd.vee......ckkkwknLRdryrrel 60 
                   + +re++w+ +a+ ++ek + ve+      +k+ +++ R++  r +
    EEA21425.1 101 SRCREQIWQPLANAIGEKWQdVEKicfergLKSLITQPRSQRGRDI 146
                   5689***********9887754446533344444555554444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (180 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       632  (0.0352502); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.43u 0.25s 00:00:00.68 Elapsed: 00:00:00.41
# Mc/sec: 1322.00
//
Query:       EEA21426.1  [L=476]
Description: probable O-sialoglycoprotein endopeptidase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-47  162.8   0.0    6.2e-46  157.3   0.0    2.7  1  Peptidase_M22  Glycoprotease family
  ------ inclusion threshold ------
      0.017   14.9   0.0      0.033   13.9   0.0    1.4  1  FGGY_C         FGGY family of carbohydrate kinases, C-termina
      0.058   13.2   0.0       0.12   12.2   0.0    1.5  1  YycC           YycC-like protein


Domain annotation for each model (and alignments):
>> Peptidase_M22  Glycoprotease family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  157.3   0.0     1e-49   6.2e-46       4     271 .]      74     428 ..      71     428 .. 0.82

  Alignments for each domain:
  == domain 1  score: 157.3 bits;  conditional E-value: 1e-49
                    XEEEEEEEEE....SSSSHHHHHHHHHHHHHHHHHHHHHHH................TSTGGGEEEEEEEEESS-HHHHHHHHHHHHHHHHHCT-- CS
  Peptidase_M22   4 anvvasqkelhakyGGvvPelasraHserllplieealaea................glsledldaIavtkgPGlftgLrvGvsfAkglalalnkP 83 
                    +n++a      +ky G++P +a + H+e l +li++al +                  ++ +  d I +t+gPG+   L vG+ +Akgla+a+++P
     EEA21426.1  74 ENITADT----RKYRGIHPIEALQSHQESLAKLIQKALCSLppddgaaashilpktgSTRRRLPDFISATRGPGMRSNLSVGLDTAKGLAVAWQIP 165
                    4444444....69*************************99999998888988888855555577******************************** PP

                    EEEEEHHHHHHHCCHCT.SEC...........SSC.EEEEESSSTEEEEEECT.TEEEEEEEESSSEHHHHHHHHHHHHT..S............. CS
  Peptidase_M22  84 lvgVnhleahalaarle.eke...........efP.vvllvsGghtqvylvke.gryeilgetlddaagealdkvarllglpy............. 152
                    lvgV+h++ah+l++rl  +             +fP +++lvsGgh++++  k+  ++eil +t d+a+ge+ldk arl+ lp              
     EEA21426.1 166 LVGVHHMQAHLLTPRLVsA-LdssspidqlqpKFPfLSVLVSGGHSMLVHTKSlLDHEILVTTADIAIGETLDKSARLI-LPEsiiesanttmygk 259
                    ***************9951.3345678888999**********************************************.6666777777776666 PP

                    ..................SCCHHHHHHHCTCS.......EET............................TEEE.CHHHHHHHHHH.ST.T..... CS
  Peptidase_M22 153 ..................pggpkieklakegkkiefprplkg............................ldfsfsGlktavlkel.ek.e..... 195
                                      p                                                   l+fsfs   + v k + +k +     
     EEA21426.1 260 lletfafpngpadyadyqP----------------------LktrgeevvkpdkdtwgwsfttpyantrdLKFSFSSVSSTVGKIMaNKaKsgvev 333
                    6666666444444443333......................0334444444444444444555555566*********99999999644537899* PP

                    ....HHHHHHHHHHHHHHHHHHHHHHHHHH............CTBSEEEEESGGGGXHHHHHCHCCHHHH...TTSEEEXXXHHHHSSXCHHHHH CS
  Peptidase_M22 196 ....vedlaasfqeavvdhlvekteralkl............pkakelvilGGvaankrLrealeeeaee...lglkliiPplkyctdnaamiaw 271
                        +  la +  +  ++hl+++t  al++            +++++lv++GGvaan+ L + l++  +    +++++i+Pp+ +ctdnaami+w
     EEA21426.1 334 tqdeRVALARESMRVCFEHLASRTIIALEQlqkqskfnhrhrQQVDTLVVSGGVAANRFLMTVLRSFLDVrgfPHIQVIAPPPYLCTDNAAMIGW 428
                    99998899999******************9********************************88875444243459*****************98 PP

>> FGGY_C  FGGY family of carbohydrate kinases, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   5.6e-06     0.033     120     169 ..     342     397 ..     315     411 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 5.6e-06
      FGGY_C 120 lahiarAaleavalqlrailealekd......sgkpldrlavdGGgskndllmqll 169
                 + + +r  +e +a ++   le+l+k+       ++++d+l+v+GG + n++lm +l
  EEA21426.1 342 ARESMRVCFEHLASRTIIALEQLQKQskfnhrHRQQVDTLVVSGGVAANRFLMTVL 397
                 556688899999999**********99999888888*****************886 PP

>> YycC  YycC-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   2.1e-05      0.12       6      38 ..     150     182 ..     144     189 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2.1e-05
        YycC   6 iSpeTAvkLskkLnvPLEhlMHmPkHILlqKla 38 
                 + ++TA+ L+ + ++PL  + Hm  H+L  +l+
  EEA21426.1 150 VGLDTAKGLAVAWQIPLVGVHHMQAHLLTPRLV 182
                 679************************987775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (476 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       388  (0.0216409); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 3121.47
//
Query:       EEA21427.1  [L=811]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.8e-11   42.3   0.7    7.2e-08   32.9   0.0    2.7  2  HET       Heterokaryon incompatibility protein (HET)


Domain annotation for each model (and alignments):
>> HET  Heterokaryon incompatibility protein (HET)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.9   0.0     4e-12   7.2e-08       1      79 [.     356     444 ..     356     456 .. 0.69
   2 !    6.7   0.8   0.00049       8.8     128     146 .]     461     479 ..     445     479 .. 0.84

  Alignments for each domain:
  == domain 1  score: 32.9 bits;  conditional E-value: 4e-12
         HET   1 YeaLSYvWgdsk...ekeeievng....klleltenledalqvlrk...lgery.....lWiDaiCInQdddkekskqvqlmadIYsnAelviv 79 
                 Y+a+S+vW d k   +  + +v +    k ++l en++      rk   +++ +      W D iC+  dd++ k+k +++m+++Ys+A++v+v
  EEA21427.1 356 YVAISHVWADGKgnpK--ANSVPEcqldKITHLVENIH---WEGRKpipSNPDLsdgigFWLDTICVPVDDKQLKKKAIANMCHVYSRAKAVLV 444
                 9*******77774331..33332232224444445554...444444443333344445*********************************98 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.00049
         HET 128 aieellespwfkRvWvlQE 146
                  +++l +s+w kR+W+ QE
  EEA21427.1 461 IVSRLYQSSWIKRLWTHQE 479
                 567899************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (811 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       432  (0.024095); expected 358.6 (0.02)
Passed bias filter:                      410  (0.022868); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.66u 0.32s 00:00:00.98 Elapsed: 00:00:00.49
# Mc/sec: 4939.39
//
Query:       EEA21428.1  [L=416]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (416 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       625  (0.0348597); expected 358.6 (0.02)
Passed bias filter:                      477  (0.0266049); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 2919.75
//
Query:       EEA21429.1  [L=126]
Description: hypothetical protein PMAA_052370 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (126 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       880  (0.0490825); expected 358.6 (0.02)
Passed bias filter:                      576  (0.0321267); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.28s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 878.81
//
Query:       EEA21430.1  [L=129]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (129 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       587  (0.0327403); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.41u 0.27s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 903.48
//
Query:       EEA21431.1  [L=1221]
Description: splicing factor 3B subunit 1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.9e-28   99.3  11.4      1e-27   97.0   1.0    3.3  3  SF3b1          Splicing factor 3B subunit 1
    5.8e-12   45.8   8.8        0.2   12.0   0.1    8.7 10  HEAT_2         HEAT repeats
    6.3e-11   42.5   0.5      0.041   14.4   0.0    6.9  6  HEAT_EZ        HEAT-like repeat
    5.1e-10   38.7  10.0      0.088   13.1   0.3    9.0  9  HEAT           HEAT repeat
    3.1e-08   33.8   1.2       0.13   12.3   0.0    6.3  6  Cnd1           non-SMC mitotic condensation complex subunit 1
    1.3e-05   24.0   0.9      0.022   13.3   0.1    3.4  3  Adaptin_N      Adaptin N terminal region
    5.7e-05   23.6   0.9        6.4    7.5   0.0    5.4  6  Vac14_Fab1_bd  Vacuolar 14 Fab1-binding region
    0.00032   20.4   0.2        1.2    8.8   0.0    4.2  5  NUC173         NUC173 domain
     0.0008   19.4   0.0     0.0036   17.3   0.0    2.0  2  UNC45-central  Myosin-binding striated muscle assembly centra
     0.0026   17.6   1.2        8.1    6.4   0.0    5.0  7  UME            UME (NUC010) domain
     0.0029   17.2   0.2       0.93    9.0   0.0    3.4  3  CLASP_N        CLASP N terminal
     0.0043   17.0   4.7       0.22   11.4   0.1    5.0  6  DUF3385        Domain of unknown function (DUF3385)
  ------ inclusion threshold ------
      0.049   12.7   0.0          2    7.4   0.0    3.2  3  MMS19_C        RNAPII transcription regulator C-terminal
      0.093   11.0   1.6        7.3    4.8   0.0    3.7  4  DRIM           Down-regulated in metastasis


Domain annotation for each model (and alignments):
>> SF3b1  Splicing factor 3B subunit 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.2      0.84   1.1e+03       4      18 ..     217     231 ..     214     243 .. 0.63
   2 !    8.5   0.6    0.0021       2.7       4      18 ..     242     256 ..     237     263 .. 0.75
   3 !   97.0   1.0   7.9e-31     1e-27       2     116 ..     260     365 ..     259     367 .. 0.85

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.84
       SF3b1   4 kkkrSrWdetpatpe 18 
                 +k++ rWd+++++ +
  EEA21431.1 217 RKRKQRWDAASEETA 231
                 799*****8887442 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0021
       SF3b1   4 kkkrSrWdetpatpe 18 
                 ++k+SrWd+tpa p+
  EEA21431.1 242 AAKKSRWDQTPAVPT 256
                 679*********984 PP

  == domain 3  score: 97.0 bits;  conditional E-value: 7.9e-31
       SF3b1   2 sakkkrSrWdetpatpeatpkgetpvgamgmatPpgalaamtPeqlqalrlekeidernrpltDeeLdallPkeGYkilepPagYepirtparkllatp 100
                 +a k+rSrWd++pa+p+    g+tpvg+ g+atP      ++P ++  + l  ++  rn + tDeeLd++lP+eGY++l+pP+gYepir+parkl+atp
  EEA21431.1 260 QAPKRRSRWDQAPAAPA---VGATPVGQPGLATP------AHP-SMGVAPLGVDL-GRNVVWTDEELDMMLPTEGYQVLQPPPGYEPIRNPARKLTATP 347
                 5679***********93...499***********......455.44555577776.69***************************************** PP

       SF3b1 101 t..plagtaegfaiqeed 116
                 +  p a+   gf++qe +
  EEA21431.1 348 AaiPSASGYGGFMMQEPE 365
                 9445555559*****986 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0       1.2   1.6e+03      11      52 ..     426     476 ..     418     511 .. 0.67
   2 !    6.7   0.1    0.0076       9.7      19      81 ..     515     582 ..     497     589 .. 0.70
   3 ?    1.2   0.0      0.38   4.9e+02      32      60 ..     606     634 ..     593     659 .. 0.75
   4 ?   -0.1   0.0         1   1.3e+03       4      52 ..     693     745 ..     689     747 .. 0.76
   5 !    8.2   0.0    0.0024       3.1      24      73 ..     760     814 ..     749     826 .. 0.84
   6 ?    5.6   0.0     0.016        21      20      58 ..     837     878 ..     835     898 .. 0.79
   7 !   10.8   0.0   0.00038      0.48       4      64 ..     898     970 ..     894     972 .. 0.82
   8 !   12.0   0.1   0.00016       0.2       2      75 ..     938    1025 ..     937    1039 .. 0.78
   9 ?    2.3   0.1      0.17   2.2e+02      32      85 ..    1048    1110 ..    1025    1113 .. 0.59
  10 ?    2.4   0.0      0.17   2.1e+02      31      69 ..    1088    1133 ..    1074    1154 .. 0.67

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 1.2
      HEAT_2  11 dpdpevrraairaLgrignp........ealpaLve.llededpavRraaa 52 
                    p  r++a+r+L + + +        ++lp+L e  led++++    ++
  EEA21431.1 426 NGTPPMRKTALRQLTDNARQfgagalfnQILPLLMEkSLEDQERHLLVKVI 476
                 556778999999999444444444556666777777666777666555555 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0076
      HEAT_2  19 aairaLgr.ignpealpaLvellededpavRraaaeaLg....aigdpealpaLkellddddddvvRe 81 
                 ++i +L++  g    + ++++ +++ d++vR + a+a +    a+g p+ lp+L++ +++++++  R 
  EEA21431.1 515 EIISNLAKaAGLAHMISTMRPDIDHVDEYVRNTTARAFAvvasALGIPALLPFLRAVCRSKKSWQARH 582
                 4444444312333445566666677789999999998864444777799*******999999988775 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.38
      HEAT_2  32 alpaLvellededpavRraaaeaLgaigd 60 
                 +++++ + l+de + vR     a++a+++
  EEA21431.1 606 LVDCIADNLSDEQAKVRTVTSLAIAALAE 634
                 68899999999999988766666666543 PP

  == domain 4  score: -0.1 bits;  conditional E-value: 1
      HEAT_2   4 LlqalendpdpevrraairaLgrignpea..lpaLve.lled..edpavRraaa 52 
                 Ll    ++pd+e ++ ++++  +++ ++    ++L e +l+d  ++ +vRr+a 
  EEA21431.1 693 LLREF-SSPDEEMKKVVLKVVSQCAQTDGvtAQYLKEnVLQDffKSFWVRRMAL 745
                 56666.789999999999999999888554466777746688888889999886 PP

  == domain 5  score: 8.2 bits;  conditional E-value: 0.0024
      HEAT_2  24 Lg.rignpealpaLvellededpavRraaaeaLgai....gdpealpaLkelldd 73 
                 Lg + g  e+l+ +v+ l+de++a R++ +e+  ++    g  +  + L+e+l d
  EEA21431.1 760 LGqKVGVGEILERIVNNLKDESEAYRKMTVETVEKLiaslGAADISERLEERLID 814
                 5633577799*********************997655555899999999999987 PP

  == domain 6  score: 5.6 bits;  conditional E-value: 0.016
      HEAT_2  20 airaLgrignp...ealpaLvellededpavRraaaeaLgai 58 
                 ++ aLg+   p   +++ +++  l+++++ vR++aa+  ++i
  EEA21431.1 837 VVNALGTRCKPylpQIVSTILWRLNHKSATVRQQAADLVSRI 878
                 6789995444334499*******************9988776 PP

  == domain 7  score: 10.8 bits;  conditional E-value: 0.00038
      HEAT_2   4 LlqalendpdpevrraairaLg.........rignp..ealpaLvellededpavRraaaeaLgaigd..peal 64 
                 L ++l   + pev   ++ aL          ++++p  ++lp L+++l++ ++ v+++ ++  g+i+d  pe++
  EEA21431.1 898 LYEYL-GEEYPEVLGSILGALRsivtvvginQMQPPirDLLPRLTPILRNRHEKVQENTIDLVGRIADrgPESV 970
                 66677.78888888888888887777777887887788****************************87556665 PP

  == domain 8  score: 12.0 bits;  conditional E-value: 0.00016
      HEAT_2    2 daLlqalendpdpevrraairaLgrignp........ealpaLvell...ededpavRraaaeaLg....aigdpealpaLkelldddd 75  
                  + L  +l +  +++v+ ++i+  gri+++        e +++++ell   + ++  +Rraa ++ g    aig +++l+ L+  l+  +
  EEA21431.1  938 PRLTPIL-RNRHEKVQENTIDLVGRIADRgpesvnarEWMRICFELLdmlKAHKKGIRRAANNTFGfiakAIGPQDVLATLLNNLRVQE 1025
                  6788999.8999************999987788888855666666665549999***********955555589999999999887654 PP

  == domain 9  score: 2.3 bits;  conditional E-value: 0.17
      HEAT_2   32 alpaLvellededpavRraaaeaLgai....gd......pealpaLkellddddddvvReaAae 85  
                  +lpaL +  + ++ +v+  + +a++ +    g+       ++ p+L+++l  d+d+v R+ Aa+
  EEA21431.1 1048 VLPALMNEYRVPELNVQNGVLKAMSFLfeyiGEmakdyvYAVTPLLEDALI-DRDQVHRQTAAS 1110
                  566666666666667777777777643333332211122446777888777.577777777765 PP

  == domain 10  score: 2.4 bits;  conditional E-value: 0.17
      HEAT_2   31 ealpaLvellededpavRraaae.....aLgaigd..pealpaLke 69  
                   + p+L ++l d d   R++aa      aLg +g+  ++a  +L+ 
  EEA21431.1 1088 AVTPLLEDALIDRDQVHRQTAASvvkhiALGVVGLgcEDAMVHLLN 1133
                  4578888888888888888888622223444334344666666655 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0       1.4   1.8e+03       3      39 ..     544     574 ..     542     585 .. 0.63
   2 ?    2.0   0.1      0.25   3.1e+02      22      48 ..     599     625 ..     596     632 .. 0.82
   3 ?   -1.1   0.0       2.2   2.8e+03      28      54 ..     768     794 ..     762     795 .. 0.86
   4 !   14.4   0.0   3.2e-05     0.041       8      55 .]     831     878 ..     830     878 .. 0.92
   5 !   12.7   0.0   0.00011      0.14      13      55 .]     919     962 ..     909     962 .. 0.84
   6 ?    3.0   0.0      0.12   1.5e+02      12      49 ..    1079    1109 ..    1062    1111 .. 0.72

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 1.4
     HEAT_EZ   3 vRraAawaLGrlaggepellqplvpeilpaLlalLnd 39 
                 vR+  a+a++ +a       ++ +p++lp+L a  ++
  EEA21431.1 544 VRNTTARAFAVVA------SALGIPALLPFLRAVCRS 574
                 6677777775333......333467888888765555 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.25
     HEAT_EZ  22 lqplvpeilpaLlalLnddsdeVRaaA 48 
                 + p+++ ++++ +  L+d++++VR+ +
  EEA21431.1 599 ILPHLKGLVDCIADNLSDEQAKVRTVT 625
                 668999******************855 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 2.2
     HEAT_EZ  28 eilpaLlalLnddsdeVRaaAagaLgn 54 
                 eil   ++ L+d+s + R+ ++ + ++
  EEA21431.1 768 EILERIVNNLKDESEAYRKMTVETVEK 794
                 799999********9999999988766 PP

  == domain 4  score: 14.4 bits;  conditional E-value: 3.2e-05
     HEAT_EZ   8 awaLGrlaggepellqplvpeilpaLlalLnddsdeVRaaAagaLgnl 55 
                 ++++G++ +  +  ++p++p+i+   l +Ln++s++VR++Aa   +++
  EEA21431.1 831 LNGFGTVVNALGTRCKPYLPQIVSTILWRLNHKSATVRQQAADLVSRI 878
                 56889999999999****************************988876 PP

  == domain 5  score: 12.7 bits;  conditional E-value: 0.00011
     HEAT_EZ  13 r.laggepellqplvpeilpaLlalLnddsdeVRaaAagaLgnl 55 
                 + + +++ +++qp + ++lp L + L++ + +V+++++   g++
  EEA21431.1 919 SiVTVVGINQMQPPIRDLLPRLTPILRNRHEKVQENTIDLVGRI 962
                 2555678899***************************9988886 PP

  == domain 6  score: 3.0 bits;  conditional E-value: 0.12
     HEAT_EZ   12 GrlaggepellqplvpeilpaLlalLnddsdeV.RaaAa 49  
                  G   +++++++  + p + +aL+     d d V R++Aa
  EEA21431.1 1079 G---EMAKDYVYAVTPLLEDALI-----DRDQVhRQTAA 1109
                  3...6667777777777888888.....*******9998 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.1       1.1   1.4e+03      13      29 ..     541     557 ..     537     559 .. 0.83
   2 ?   -1.6   0.0       3.6   4.6e+03       1      26 [.     564     590 ..     564     591 .. 0.77
   3 !   13.1   0.3   6.9e-05     0.088       1      29 [.     606     634 ..     606     636 .. 0.94
   4 ?   -0.9   0.0       2.2   2.8e+03       1      29 [.     689     717 ..     689     718 .. 0.88
   5 !    6.9   0.0    0.0071         9       1      28 [.     769     796 ..     769     799 .. 0.90
   6 !    6.5   0.0    0.0094        12       6      27 ..     858     878 ..     852     881 .. 0.84
   7 ?    2.2   0.0      0.22   2.8e+02       1      29 [.     936     964 ..     936     965 .. 0.94
   8 ?   -1.1   0.0       2.6   3.3e+03       5      29 ..     982    1006 ..     981    1008 .. 0.84
   9 ?    5.1   0.0     0.026        33       3      28 ..    1091    1116 ..    1089    1119 .. 0.90

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 1.1
                 SHHHHHHHHHHHHHHHH CS
        HEAT  13 speVReaAakaLgalae 29 
                 +  VR ++a+a++ +a+
  EEA21431.1 541 DEYVRNTTARAFAVVAS 557
                 678*********99887 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 3.6
                 HHHHHHHHHT-.SSHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsD.pspeVReaAakaLga 26 
                 llP+l   +++ +s++ R + +k + +
  EEA21431.1 564 LLPFLRAVCRSkKSWQARHTGVKIVQQ 590
                 799999999665999999887776655 PP

  == domain 3  score: 13.1 bits;  conditional E-value: 6.9e-05
                 HHHHHHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgalae 29 
                 l++++  +lsD+ ++VR  + +a++alae
  EEA21431.1 606 LVDCIADNLSDEQAKVRTVTSLAIAALAE 634
                 68899**********************98 PP

  == domain 4  score: -0.9 bits;  conditional E-value: 2.2
                 HHHHHHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgalae 29 
                 ++ +ll+  s+p+ e  + ++k + + a+
  EEA21431.1 689 IMEILLREFSSPDEEMKKVVLKVVSQCAQ 717
                 788999999*********99999998876 PP

  == domain 5  score: 6.9 bits;  conditional E-value: 0.0071
                 HHHHHHHHHT-SSHHHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgala 28 
                 +l  ++++l+D+s   R+++++++ +l+
  EEA21431.1 769 ILERIVNNLKDESEAYRKMTVETVEKLI 796
                 7899******************998876 PP

  == domain 6  score: 6.5 bits;  conditional E-value: 0.0094
                 HHHHT-SSHHHHHHHHHHHHHH CS
        HEAT   6 lkllsDpspeVReaAakaLgal 27 
                 ++ l+++s+ VR+ Aa  + ++
  EEA21431.1 858 WR-LNHKSATVRQQAADLVSRI 878
                 55.8************999887 PP

  == domain 7  score: 2.2 bits;  conditional E-value: 0.22
                 HHHHHHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgalae 29 
                 llP l   l+  + +V e+++  +g++a 
  EEA21431.1 936 LLPRLTPILRNRHEKVQENTIDLVGRIAD 964
                 7999**********************985 PP

  == domain 8  score: -1.1 bits;  conditional E-value: 2.6
                  HHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT    5 llkllsDpspeVReaAakaLgalae 29  
                  ll +l+     +R+aA +++g +a+
  EEA21431.1  982 LLDMLKAHKKGIRRAANNTFGFIAK 1006
                  677888888889********99987 PP

  == domain 9  score: 5.1 bits;  conditional E-value: 0.026
                  HHHHHHHT-SSHHHHHHHHHHHHHHH CS
        HEAT    3 PlllkllsDpspeVReaAakaLgala 28  
                  Pll  +l D +   R++Aa  + ++a
  EEA21431.1 1091 PLLEDALIDRDQVHRQTAASVVKHIA 1116
                  999*****************999998 PP

>> Cnd1  non-SMC mitotic condensation complex subunit 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0       3.3   4.2e+03     116     145 ..     452     479 ..     403     485 .. 0.68
   2 ?   -1.2   0.0       1.5   1.9e+03      22      46 ..     529     553 ..     526     561 .. 0.80
   3 !   12.3   0.0   9.9e-05      0.13      35     147 ..     578     717 ..     543     736 .. 0.73
   4 ?    4.3   0.0      0.03        38      21      50 ..     768     797 ..     764     824 .. 0.88
   5 ?    5.2   0.1     0.015        19      23      88 ..     853     923 ..     836    1036 .. 0.69
   6 ?    2.5   0.0      0.11   1.4e+02      18      48 ..    1085    1115 ..    1063    1159 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 3.3
        Cnd1 116 qitilefLlsyipkdkqeaeslveklcprl 145
                 +++il +L++   +d++   +l+ k+++r+
  EEA21431.1 452 FNQILPLLMEKSLEDQE--RHLLVKVIDRV 479
                 56677777777666666..77777777665 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 1.5
        Cnd1  22 lvepLrkrLkDedpyVRktaaivva 46 
                 +++ +r  +   d+yVR+t+a ++a
  EEA21431.1 529 MISTMRPDIDHVDEYVRNTTARAFA 553
                 6677777888889******997765 PP

  == domain 3  score: 12.3 bits;  conditional E-value: 9.9e-05
        Cnd1  35 pyVRktaaivvakL.ilnd...mvkekgflselaklleDenprVvanalaalteiseksenaiynllpdiisklsd....................... 106
                  + R t + +v ++ il++   +   kg+++ +a+ l+De+++V++ + +a+  ++e ++   ++++ di++ l +                       
  EEA21431.1 578 WQARHTGVKIVQQIpILMGcaiLPHLKGLVDCIADNLSDEQAKVRTVTSLAIAALAEAANPYGIESFDDILNPLWTgarkqrgkglagflkavgyiipl 676
                 4567777888888887777332334799******************************988899**********9987777777777766666666666 PP

        Cnd1 107 alnecsewgqitilefLlsyipkdkqeaeslveklcprlqh 147
                   +e  +    +i+e+Ll+  ++ ++e++++v k++++  +
  EEA21431.1 677 MDEEYANYYTSQIMEILLREFSSPDEEMKKVVLKVVSQCAQ 717
                 44557777778888888887777777788888888877654 PP

  == domain 4  score: 4.3 bits;  conditional E-value: 0.03
        Cnd1  21 ylvepLrkrLkDedpyVRktaaivvakLil 50 
                 +++e++ + LkDe++  Rk ++ +v kLi 
  EEA21431.1 768 EILERIVNNLKDESEAYRKMTVETVEKLIA 797
                 57889999********************75 PP

  == domain 5  score: 5.2 bits;  conditional E-value: 0.015
        Cnd1  23 vepLrkrLkDedpyVRktaaivvakL.ilndmvkekgflselakll....eDenprVvanalaalteisek 88 
                 v+ +  rL+ ++++VR++aa +v+++ + ++ + e  ++ +l  ll     +e p+V  + l al  i + 
  EEA21431.1 853 VSTILWRLNHKSATVRQQAADLVSRItMVMKQCGEDALMGKLSVLLyeylGEEYPEVLGSILGALRSIVTV 923
                 55666677888888888888888888877788887777777666552222455566655555555555554 PP

  == domain 6  score: 2.5 bits;  conditional E-value: 0.11
        Cnd1   18 lveylvepLrkrLkDedpyVRktaaivvakL 48  
                   v ++++ L+ +L D+d+  R+taa vv ++
  EEA21431.1 1085 YVYAVTPLLEDALIDRDQVHRQTAASVVKHI 1115
                  56677888999*****************997 PP

>> Adaptin_N  Adaptin N terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0     0.069        88      80     179 ..     529     635 ..     518     654 .. 0.76
   2 !   13.3   0.1   1.7e-05     0.022     264     371 ..     685     799 ..     662     829 .. 0.84
   3 !    5.4   0.0    0.0043       5.5     229     332 ..     930    1043 ..     844    1117 .. 0.61

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.069
                 CCHHHHHHCCSSSHHHHHHHHHHHCCC--CCCHHHHHHHHHHHHT-SSH.HHHHHHHHHHHHCCCC.....CHHCCCCC.HHHHHHHCTT-SS...HHH CS
   Adaptin_N  80 vtnslqkDlkdpnqlirglALrvLssirvpelaedlapaikkllkdrsp.yvrkkAalailklykk.....dpdllrkq.lveeikellsdkd...pgv 168
                 ++++++ D  + ++++r+ + r+ + + ++   ++l+p ++++ +++++ + r + + ++ ++  +      p+l   + lv++i + lsd++     v
  EEA21431.1 529 MISTMRPDIDHVDEYVRNTTARAFAVVASALGIPALLPFLRAVCRSKKSwQARHTGVKIVQQIPILmgcaiLPHL---KgLVDCIADNLSDEQakvRTV 624
                 6899999**********************9999************999976666666555555333433434555...248999999999999333355 PP

                 HHHHHHHHHHH CS
   Adaptin_N 169 vlaAvalleei 179
                 ++ A+a+l e 
  EEA21431.1 625 TSLAIAALAEA 635
                 66666666665 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 1.7e-05
                 HHHCCHHCHHHHHHSSCCTCHHHHHCHHHHHHHHX.......XTTTTTTTCCCCSXX.TTSXHHHHHHHHHHHCCCXXTTTHHHHHHHHHHHTTSSXXH CS
   Adaptin_N 264 livlavnaLvrllsskdenlryvaLrtllkivkke.......pkavqhldlkifllk.tdddvsirlkaldlllklvdesNvkeivkeLkkyvkevade 354
                   ++++++L r  ss+de ++ v+L+  ++ ++++       ++ v ++ +k+f ++ +  d    +  +++ ++l+++  v ei++ + + +k+ ++ 
  EEA21431.1 685 YTSQIMEILLREFSSPDEEMKKVVLKVVSQCAQTDgvtaqylKENVLQDFFKSFWVRrMALDKRNYRQVVETTVDLGQKVGVGEILERIVNNLKDESEA 783
                 5689999***************************8888888889999999****9973577999999**************************888666 PP

                 HHHHHHHHHHHHHHHHS CS
   Adaptin_N 355 dfksklvkaIgrlaekf 371
                  +++++v+++ +l+ + 
  EEA21431.1 784 -YRKMTVETVEKLIASL 799
                 .*********9998877 PP

  == domain 3  score: 5.4 bits;  conditional E-value: 0.0043
                  ....HHHHHHHCGGCGCSSCHHHHHHHHHCCHCCCCST......HHHCCHHCHHHHHHSSCCTCHHHHHCHHHHHHHHX.XTTTTTTTCCCCSXXTT CS
   Adaptin_N  229 k...kellesllnllqssnnaVlletvnlivelapkne......livlavnaLvrllsskdenlryvaLrtllkivkke.pkavqhldlkifllktd 315 
                  +   ++ll++l++ l+++++ V  +t+ l+ ++a++ +        ++++  L ++l+ +++++r +a +t+  i+k   p+ v    l+  +++  
  EEA21431.1  930 QppiRDLLPRLTPILRNRHEKVQENTIDLVGRIADRGPesvnarEWMRICFELLDMLKAHKKGIRRAANNTFGFIAKAIgPQDVLATLLNNLRVQER 1026
                  1233689999999999999999999999999888776667777767889999999999999999999999998888876677777777777777744 PP

                  SXHHHHHHHHHHHCCCX CS
   Adaptin_N  316 ddvsirlkaldlllklv 332 
                  +++     a+ ++ +++
  EEA21431.1 1027 QSRVCTAVAIGIVAETC 1043
                  44444445555555555 PP

>> Vac14_Fab1_bd  Vacuolar 14 Fab1-binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.0      0.43   5.6e+02      17      59 ..     483     525 ..     473     537 .. 0.86
   2 ?    6.1   0.0     0.013        17       2      73 ..     580     651 ..     579     656 .. 0.88
   3 ?    0.3   0.0      0.83   1.1e+03      17      43 ..     676     704 ..     657     740 .. 0.79
   4 ?   -0.2   0.0       1.2   1.5e+03      17      50 ..     760     791 ..     752     802 .. 0.77
   5 !    7.5   0.0     0.005       6.4       8      60 ..     832     884 ..     829     900 .. 0.86
   6 ?   -2.9   0.0       8.5   1.1e+04       4      47 ..    1065    1108 ..    1062    1116 .. 0.62

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.43
  Vac14_Fab1_bd  17 lekkikeyleeivkpvlkcfsDkdsrvRyyacEslyniakvak 59 
                    l+  +++y+++i+ ++   + D+d   R    E + n+ak+a 
     EEA21431.1 483 LDDLVRPYTHKILVVIEPLLIDQDYYARVEGREIISNLAKAAG 525
                    56668999*******************************9986 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.013
  Vac14_Fab1_bd   2 arkggligLaavaialekkikeyleeivkpvlkcfsDkdsrvRyyacEslyniakvakgevlkllneifdal 73 
                    ar+ g+  +  + i ++ +i ++l+ +v+ + + +sD++++vR  ++ ++  +a +a+   ++ + +i++ l
     EEA21431.1 580 ARHTGVKIVQQIPILMGCAILPHLKGLVDCIADNLSDEQAKVRTVTSLAIAALAEAANPYGIESFDDILNPL 651
                    677888888889999999999**********************99999999999999999999999998766 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.83
  Vac14_Fab1_bd  17 lekk..ikeyleeivkpvlkcfsDkdsrv 43 
                    l  +  ++ y+++i++++l+ fs  d+++
     EEA21431.1 676 LMDEeyANYYTSQIMEILLREFSSPDEEM 704
                    44444588899999999999999888875 PP

  == domain 4  score: -0.2 bits;  conditional E-value: 1.2
  Vac14_Fab1_bd  17 lekkikeyleeivkpvlkcfsDkdsrvRyyacEs 50 
                    l++k+   + ei++ +++ ++D+++  R  ++E+
     EEA21431.1 760 LGQKV--GVGEILERIVNNLKDESEAYRKMTVET 791
                    55443..367899999******999999887776 PP

  == domain 5  score: 7.5 bits;  conditional E-value: 0.005
  Vac14_Fab1_bd   8 igLaavaialekkikeyleeivkpvlkcfsDkdsrvRyyacEslyniakvakg 60 
                     g+ +v  al+++ k+yl +iv+++l  ++ k++ vR  a++ +  i+ v+k+
     EEA21431.1 832 NGFGTVVNALGTRCKPYLPQIVSTILWRLNHKSATVRQQAADLVSRITMVMKQ 884
                    577788889*******************************9988777766654 PP

  == domain 6  score: -2.9 bits;  conditional E-value: 8.5
  Vac14_Fab1_bd    4 kggligLaavaialekkikeyleeivkpvlkcfsDkdsrvRyya 47  
                     +g l ++ ++   +++ +k+y+  + + + +++ D+d+  R +a
     EEA21431.1 1065 NGVLKAMSFLFEYIGEMAKDYVYAVTPLLEDALIDRDQVHRQTA 1108
                     55555565555566666666666666666667777776666555 PP

>> NUC173  NUC173 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0       3.9     5e+03       8      54 ..     531     578 ..     525     591 .. 0.75
   2 ?   -0.4   0.0      0.61   7.8e+02      40      76 ..     766     802 ..     725     809 .. 0.79
   3 !    5.8   0.0    0.0074       9.5      21      81 ..     830     893 ..     810     923 .. 0.79
   4 !    8.8   0.0   0.00092       1.2      10      89 ..     944    1024 ..     935    1031 .. 0.67
   5 ?   -2.7   0.0         3   3.8e+03      21      54 ..    1067    1107 ..    1062    1128 .. 0.50

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 3.9
      NUC173   8 slLslkyqaawkevlevlsalfeklgkrs.spllkkilktlgelrese 54 
                 s+++  + ++ ++v ++++++f ++ ++   p+l + l+ ++  ++s 
  EEA21431.1 531 STMRPDIDHVDEYVRNTTARAFAVVASALgIPALLPFLRAVCRSKKSW 578
                 566777778888888888888988888887888899888888777665 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.61
      NUC173  40 lkkilktlgelreseefelkkeadevigaairamGpe 76 
                 + +il+++ +  ++e+ +++k   e++ + i+++G+ 
  EEA21431.1 766 VGEILERIVNNLKDESEAYRKMTVETVEKLIASLGAA 802
                 7788888888888887789999999999999999986 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.0074
      NUC173  21 vlevlsalfeklgkrsspllkkilktlgelreseefelkkeadev...igaairamGpevvLev 81 
                 +l+ + +++++lg r++p+l +i+ t+    ++++++ +++a +    i + ++ +G ++++  
  EEA21431.1 830 ILNGFGTVVNALGTRCKPYLPQIVSTILWRLNHKSATVRQQAADLvsrITMVMKQCGEDALMGK 893
                 67888999******************98665555767777766651225567788888777655 PP

  == domain 4  score: 8.8 bits;  conditional E-value: 0.00092
      NUC173   10 Lslkyqaawkevlevlsalfeklgkrs.spllkkilktlgelreseefelkkeadevigaairamGpevvLevlPLnleee 89  
                  L+ +++++ ++++ ++ ++ ++  +++ +   ++i  +l ++ +++++  +++a++++g++ +a+Gp+ vL++l  nl  +
  EEA21431.1  944 LRNRHEKVQENTIDLVGRIADRGPESVnAREWMRICFELLDMLKAHKKGIRRAANNTFGFIAKAIGPQDVLATLLNNLRVQ 1024
                  55566666666666666666666555532234444444445555555579**********************998777744 PP

  == domain 5  score: -2.7 bits;  conditional E-value: 3
      NUC173   21 vlevlsalfeklgkrs.......spllkkilktlgelrese 54  
                  vl+ +s lfe +g+ +       +pll+++l + ++++ + 
  EEA21431.1 1067 VLKAMSFLFEYIGEMAkdyvyavTPLLEDALIDRDQVHRQT 1107
                  55555556665555552111111444555554444444443 PP

>> UNC45-central  Myosin-binding striated muscle assembly central
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0   2.8e-06    0.0036       3     112 ..     607     716 ..     599     731 .. 0.92
   2 ?   -2.5   0.0       3.4   4.3e+03       2      40 ..     852     889 ..     851     907 .. 0.74

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 2.8e-06
                    HHHHHHHC-T---TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH...SCCTHHHHHHHHHHHHHHHHSSHHHHHHHHTSTTHHHHHHHHHHS. CS
  UNC45-central   3 ldlllkfldmrqpesvrslallilsklldaakeefeeaiseflesll...ekgdeddllnalsvltalFpvvpdvasalflsegflesllelvesk 95 
                    +d + ++l  +++++vr+  +l++++l +aa+  ++e ++++l+ l    +k++++ l  +l+++  + p++ +  ++ ++s +++e+ll   +s 
     EEA21431.1 607 VDCIADNLS-DEQAKVRTVTSLAIAALAEAANPYGIESFDDILNPLWtgaRKQRGKGLAGFLKAVGYIIPLMDEEYANYYTS-QIMEILLREFSS- 699
                    566777777.699**********************************99999**************************9999.9**********9. PP

                    S-HHHHHHHHHHHHTT- CS
  UNC45-central  96 kskkvqlaalellsaAc 112
                     ++++++++l+++s+ +
     EEA21431.1 700 PDEEMKKVVLKVVSQCA 716
                    ************99854 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 3.4
                    HHHHHHHHC-T---TTHHHHHHHHHHHHHHHHHHHHHHH CS
  UNC45-central   2 hldlllkfldmrqpesvrslallilsklldaakeefeea 40 
                    +++++l  l++ ++++vr++a  ++s++    k+ +e+a
     EEA21431.1 852 IVSTILWRLNH-KSATVRQQAADLVSRITMVMKQCGEDA 889
                    56778888886.999999999999998886666655555 PP

>> UME  UME (NUC010) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       5.5     7e+03      64      85 ..     539     562 ..     513     572 .. 0.52
   2 ?   -2.5   0.0       3.8   4.8e+03       4      36 ..     601     632 ..     599     635 .. 0.72
   3 ?    1.2   0.0      0.27   3.5e+02      33      71 ..     667     708 ..     661     717 .. 0.80
   4 ?   -2.3   0.0       3.2   4.1e+03       9      44 ..     769     800 ..     766     809 .. 0.62
   5 !    6.4   0.0    0.0063       8.1      26      71 ..     824     871 ..     812     902 .. 0.76
   6 ?   -2.9   0.0       5.2   6.6e+03      54      70 ..    1013    1029 ..     975    1036 .. 0.59
   7 ?    3.6   0.0     0.049        63      19      64 ..    1055    1099 ..    1041    1112 .. 0.79

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 5.5
         UME  64 i..delrsaalsvWatllsnlede 85 
                 +  + +r+ + +++a+ +s l + 
  EEA21431.1 539 HvdEYVRNTTARAFAVVASALGIP 562
                 222334444444454444444444 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 3.8
         UME   4 qhilgiltrlseklndshgkkslaekkraikal 36 
                 +h+ g++  ++++l+d + k        ai al
  EEA21431.1 601 PHLKGLVDCIADNLSDEQAKVR-TVTSLAIAAL 632
                 6889999999999999998843.3445555555 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.27
         UME  33 ikaleeliklagss.issalpqimacLqsalei..delrsaa 71 
                 +ka + +i l+ ++ ++ +  qim +L   +++  +e++++ 
  EEA21431.1 667 LKAVGYIIPLMDEEyANYYTSQIMEILLREFSSpdEEMKKVV 708
                 899999*****9886899999*****9988877434555555 PP

  == domain 4  score: -2.3 bits;  conditional E-value: 3.2
         UME   9 iltrlseklndshgkkslaekkraikaleeliklag 44 
                 il r++++l+d ++      +k +++  e+li  +g
  EEA21431.1 769 ILERIVNNLKDESEA----YRKMTVETVEKLIASLG 800
                 667777777666554....56666666666665444 PP

  == domain 5  score: 6.4 bits;  conditional E-value: 0.0063
         UME  26 laekkraikaleeliklagssissalpqimacLqsalei..delrsaa 71 
                   e + ++++ + +++ +g++ +++lpqi+++    l++  + +r++a
  EEA21431.1 824 SVEDIVILNGFGTVVNALGTRCKPYLPQIVSTILWRLNHksATVRQQA 871
                 4588899***********************999988888334555555 PP

  == domain 6  score: -2.9 bits;  conditional E-value: 5.2
         UME   54 imacLqsaleidelrsa 70  
                  ++a+L + l+ +e +s 
  EEA21431.1 1013 VLATLLNNLRVQERQSR 1029
                  55555555555554444 PP

  == domain 7  score: 3.6 bits;  conditional E-value: 0.049
         UME   19 dshgkkslaekkraikaleeliklagssissalpqimacLqsalei 64  
                  + +   +l+ +  ++ka+++l++++g+ ++ ++  ++ +L +al +
  EEA21431.1 1055 EYRVP-ELNVQNGVLKAMSFLFEYIGEMAKDYVYAVTPLLEDALID 1099
                  55555.67788899**************999999999999999865 PP

>> CLASP_N  CLASP N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0     0.034        44     140     196 ..     574     625 ..     523     642 .. 0.58
   2 ?   -0.9   0.0      0.78   9.9e+02      84     121 ..     841     878 ..     836     897 .. 0.69
   3 !    9.0   0.0   0.00073      0.93      71     151 ..     953    1033 ..     932    1044 .. 0.77

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.034
     CLASP_N 140 qdKnvqpReysaiwLkilltrfeshkskleasllldliekslkkgleDanptVReta 196
                 + K+ q+R + ++ ++++ + ++    ++  +l  + +++++   l+D + +VR ++
  EEA21431.1 574 SKKSWQARHTGVKIVQQIPILMG---CAILPHL--KGLVDCIADNLSDEQAKVRTVT 625
                 44566666666666666666666...3333333..4456677777777777776654 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.78
     CLASP_N  84 lkeqldpmveillptLlkllgdtKkiisqnanqalaal 121
                 l+++ +p++ ++++t+l +l  +   ++q+a+  ++ +
  EEA21431.1 841 LGTRCKPYLPQIVSTILWRLNHKSATVRQQAADLVSRI 878
                 56666677777777777777777777777777666555 PP

  == domain 3  score: 9.0 bits;  conditional E-value: 0.00073
     CLASP_N   71 stgchllkelaiqlkeqldpm.veillptLlkllgdtKkiisqnanqalaallsnasfsprilqvlsvalqdKnvqpReysa 151 
                   + + l+ ++a    e++ +    +++  Ll++l ++Kk i+ +an+++  + ++++  +++l  l + l     q R + a
  EEA21431.1  953 ENTIDLVGRIADRGPESVNAReWMRICFELLDMLKAHKKGIRRAANNTFGFIAKAIG-PQDVLATLLNNLRVQERQSRVCTA 1033
                  56667777777777777666667788889**************************99.777766666655555666666655 PP

>> DUF3385  Domain of unknown function (DUF3385)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       1.3   1.7e+03      73     130 ..     437     495 ..     409     501 .. 0.75
   2 ?   -0.7   0.0      0.95   1.2e+03       2      34 ..     555     587 ..     554     634 .. 0.88
   3 ?    0.7   0.0      0.35   4.5e+02      77     134 ..     675     735 ..     655     755 .. 0.64
   4 !   11.4   0.1   0.00017      0.22      40     149 ..     744     871 ..     743     883 .. 0.50
   5 ?   -1.3   0.0       1.4   1.8e+03     108     150 ..     914     956 ..     889     963 .. 0.70
   6 ?   -0.1   0.0      0.61   7.8e+02      78     136 ..    1039    1096 ..     981    1116 .. 0.70

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 1.3
     DUF3385  73 vglspsneeyyptvvinaLlrilkdpsls.shhaavveaimnifktlglkcvpfLdqii 130
                  +l+    ++ +   +n++l +l ++sl+ + ++  v++i  ++ +l+  + p+ ++i+
  EEA21431.1 437 RQLTDNARQFGAGALFNQILPLLMEKSLEdQERHLLVKVIDRVLYKLDDLVRPYTHKIL 495
                 45555556666777889999999999999677777888888888888888888877776 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.95
     DUF3385   2 vdPyleypqLLelLlnilkteqsqsirrevikl 34 
                 v   l  p LL  L  + ++++s++ r   +k+
  EEA21431.1 555 VASALGIPALLPFLRAVCRSKKSWQARHTGVKI 587
                 566677899999999999999999999988876 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 0.35
     DUF3385  77 psneeyyptvvinaLlril..kdpslsshhaavveaimnifktlglkcvpfLd.qiipall 134
                 p  +e y+ +  +++++il  + +s ++  ++vv  +++ + + +    ++L+ +++++++
  EEA21431.1 675 PLMDEEYANYYTSQIMEILlrEFSSPDEEMKKVVLKVVSQCAQTDGVTAQYLKeNVLQDFF 735
                 4446666666777777776432233335666666666666666565556665414555555 PP

  == domain 4  score: 11.4 bits;  conditional E-value: 0.00017
     DUF3385  40 ALDPykhkqveer.................aedkkrreeaaretdlsllmvglspsneeyyptvvinaLlril................kdpslsshha 105
                 ALD  +++qv e+                                      +  + + e y +++++++ +++                 d  l   ++
  EEA21431.1 744 ALDKRNYRQVVETtvdlgqkvgvgeileriV--------------------NNLKDESEAYRKMTVETVEKLIaslgaadiserleerlIDGVLLAFQE 822
                 6666666666655333333332222222221....................222333333333333332222223344444444444443444444444 PP

     DUF3385 106 avveai......mnifktlglkcvpfLdqiipallsvirtteesnlrefl 149
                 + ve i       ++++ lg++c p+L+qi++++l  +++ ++ ++r+  
  EEA21431.1 823 QSVEDIvilngfGTVVNALGTRCKPYLPQIVSTILWRLNHKSA-TVRQQA 871
                 444444444444899999****************998887665.444443 PP

  == domain 5  score: -1.3 bits;  conditional E-value: 1.4
     DUF3385 108 veaimnifktlglkc.vpfLdqiipallsvirtteesnlrefll 150
                 + a+ +i++ +g+++  p ++ ++p+l  ++r+ +e +++e  +
  EEA21431.1 914 LGALRSIVTVVGINQmQPPIRDLLPRLTPILRNRHE-KVQENTI 956
                 445566677777766566777777777777777666.6666555 PP

  == domain 6  score: -0.1 bits;  conditional E-value: 0.61
     DUF3385   78 sneeyyptvvinaLlrilkdpslsshhaavveaimnifktlglkcvpfLdqiipallsv 136 
                    e   p +v+ aL++  + p l+  +++v++a+ + f+ +g     ++  + p l  +
  EEA21431.1 1039 VAETCAPFTVLPALMNEYRVPELN-VQNGVLKAMSFLFEYIGEMAKDYVYAVTPLLEDA 1096
                  456666778888999999999988.7889999999999998888888888877766555 PP

>> MMS19_C  RNAPII transcription regulator C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.0    0.0016         2     330     409 ..     644     726 ..     643     738 .. 0.88
   2 ?    0.3   0.1      0.23   2.9e+02      59     126 ..     783     840 ..     741     885 .. 0.46
   3 ?   -2.7   0.0       1.9   2.4e+03     332     363 ..    1047    1078 ..    1047    1115 .. 0.78

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0016
     MMS19_C 330 FstvlpklvegfkssdsetkenyLvALshllkhvPkslllpeLptLlPlLlqaLdlpdaevkastLetlksilees...pslv 409
                 F+++l+ l +g++++  +  + +L A   ++  + +++   + ++++ +Ll+  + pd+e+k+ +L++++  ++++   ++ +
  EEA21431.1 644 FDDILNPLWTGARKQRGKGLAGFLKAVGYIIPLMDEEYANYYTSQIMEILLREFSSPDEEMKKVVLKVVSQCAQTDgvtAQYL 726
                 8889999999999999999999************************************************9999532334444 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.23
     MMS19_C  59 ayahailstllkllekkqtdlekeellnsyydrivprlltlvvsaastsssiltddrllevlgriinl 126
                 ay  + ++t+ kl++           ++ +++r+  rl++ v+ a +++    +d  +l+  g ++n+
  EEA21431.1 783 AYRKMTVETVEKLIASLG--------AADISERLEERLIDGVLLAFQEQ--SVEDIVILNGFGTVVNA 840
                 444444444444444433........24444444444444433333332..22222222333333222 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 1.9
     MMS19_C  332 tvlpklvegfkssdsetkenyLvALshllkhv 363 
                  tvlp l+++++  + + ++ +L A+s l + +
  EEA21431.1 1047 TVLPALMNEYRVPELNVQNGVLKAMSFLFEYI 1078
                  68999*****9999999999999999887766 PP

>> DRIM  Down-regulated in metastasis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.1      0.83   1.1e+03      89     108 ..     462     481 ..     435     512 .. 0.69
   2 ?    1.2   0.1     0.067        86     430     523 ..     684     802 ..     674     827 .. 0.49
   3 ?    4.8   0.0    0.0057       7.3     194     237 ..     830     873 ..     748     920 .. 0.84
   4 ?    1.2   0.0     0.069        89     376     441 ..     927     985 ..     904    1117 .. 0.66

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.83
        DRIM  89 esieeehraelmpvllRiLy 108
                 +s+e+++r+ l+ v+ R+Ly
  EEA21431.1 462 KSLEDQERHLLVKVIDRVLY 481
                 45566666666666666665 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.067
        DRIM 430 sLldlllplLrkpsrrvsektkvelLkilenllrlydedevdlpekllktlsslfsr....lkdreaRklLcev...................lkalak 505
                   ++ ++ +L ++ ++ +e+ k  +Lk++++  +    ++  l+e++l+ + + f +    l++r+ R++  ++                   l     
  EEA21431.1 684 YYTSQIMEILLREFSSPDEEMKKVVLKVVSQCAQTDGVTAQYLKENVLQDFFKSFWVrrmaLDKRNYRQVVETTvdlgqkvgvgeilerivnnL----- 777
                 5555566666666666666666666666666666633344446666666666666555555555555555544433344444444422221111..... PP

        DRIM 506 kdp.........eleevadllsdLNay 523
                   +         ++e v++l++ L a 
  EEA21431.1 778 --KdeseayrkmTVETVEKLIASLGAA 802
                 ..1111222222234444444444444 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.0057
        DRIM 194 flnlledvlkelgsklapflpkllklllyclaaaqrrlksssee 237
                 +ln   +v++ lg++ +p+lp++++++l  l++ ++ +++++++
  EEA21431.1 830 ILNGFGTVVNALGTRCKPYLPQIVSTILWRLNHKSATVRQQAAD 873
                 5788899*********************9998888777776554 PP

  == domain 4  score: 1.2 bits;  conditional E-value: 0.069
        DRIM 376 elLlphvsslLeylsalleksaaskkdkskellereleiLsrlaplvedseqassLldlllplLrk 441
                 + ++p + +lL +l+ +l++         +++ e  ++++ r+a+   +s +a++ +++++ lL+ 
  EEA21431.1 927 NQMQPPIRDLLPRLTPILRNR-------HEKVQENTIDLVGRIADRGPESVNAREWMRICFELLDM 985
                 557788888888888888766.......24578888888888888888888888777777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1221 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       882  (0.049194); expected 358.6 (0.02)
Passed bias filter:                      589  (0.0328518); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 1.01u 0.30s 00:00:01.31 Elapsed: 00:00:00.46
# Mc/sec: 7926.93
//
Query:       EEA21432.1  [L=348]
Description: C2H2 conidiation transcription factor FlbC [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.9e-10   40.7  14.7    2.3e-05   24.6   0.4    3.6  3  zf-H2C2_2    Zinc-finger double domain
    4.8e-10   39.3  11.5    2.2e-05   24.7   4.5    3.0  2  zf-C2H2      Zinc finger, C2H2 type
    7.6e-07   29.4  10.7     0.0013   19.4   3.2    2.8  2  zf-C2H2_4    C2H2-type zinc finger
    5.7e-06   26.5   1.3    1.8e-05   25.0   1.3    1.9  1  zf-met       Zinc-finger of C2H2 type
    0.00012   22.0   2.4    0.00012   22.0   2.4    3.2  3  zf-C2H2_6    C2H2-type zinc finger
    0.00073   19.8   1.8    0.00073   19.8   1.8    2.4  2  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
  ------ inclusion threshold ------
      0.089   12.7   4.2        2.9    7.9   0.4    2.5  2  zf-C2HC_2    zinc-finger of a C2HC-type
       0.12   12.7   2.9       0.11   12.9   1.3    1.7  1  zf-C2H2_2    C2H2 type zinc-finger (2 copies)
       0.26   10.4   0.0       0.35   10.0   0.0    1.1  1  Actin_micro  Putative actin-like family
       0.34   10.7   7.2        6.6    6.6   0.8    2.8  2  zf-C2H2_11   zinc-finger C2H2-type


Domain annotation for each model (and alignments):
>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.3   1.0    0.0001      0.18      12      26 .]     280     294 ..     277     294 .. 0.90
   2 !   24.6   0.4   1.3e-08   2.3e-05       1      24 [.     297     322 ..     297     323 .. 0.87
   3 !   11.7   1.2   0.00016      0.29       1      13 [.     327     339 ..     327     340 .. 0.94

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.0001
   zf-H2C2_2  12 ekpyeCplCdkaFkt 26 
                 +k+++C++Cdk+F++
  EEA21432.1 280 QKKHKCKVCDKRFTR 294
                 689**********85 PP

  == domain 2  score: 24.6 bits;  conditional E-value: 1.3e-08
   zf-H2C2_2   1 nLrrHirkHtgekpyeCp..lCdkaF 24 
                 +L+ H+++Htgekpy C+   C+  F
  EEA21432.1 297 SLQTHMYSHTGEKPYACDveGCGRHF 322
                 5999**************76688877 PP

  == domain 3  score: 11.7 bits;  conditional E-value: 0.00016
   zf-H2C2_2   1 nLrrHirkHtgek 13 
                 nLrrH ++H+gek
  EEA21432.1 327 NLRRHKKVHKGEK 339
                 8***********9 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   4.5   1.2e-08   2.2e-05       1      23 []     283     305 ..     283     305 .. 0.97
   2 !   17.9   0.6   1.6e-06    0.0029       1      23 []     311     335 ..     311     335 .. 0.96

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 1.2e-08
                 EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirtH 23 
                 +kC++C+k+F+r+s+L++H+ +H
  EEA21432.1 283 HKCKVCDKRFTRPSSLQTHMYSH 305
                 79******************999 PP

  == domain 2  score: 17.9 bits;  conditional E-value: 1.6e-06
                 EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirtH 23 
                 y C+  +Cg+ F+  snL+rH ++H
  EEA21432.1 311 YACDveGCGRHFSVVSNLRRHKKVH 335
                 789999*****************99 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   3.2     7e-07    0.0013       1      23 [.     283     305 ..     283     306 .. 0.96
   2 !   13.8   0.8   4.5e-05      0.08       1      23 [.     311     335 ..     311     336 .. 0.91

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 7e-07
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlkth 23 
                 +kC++C+k+F+++++L++H+ +h
  EEA21432.1 283 HKCKVCDKRFTRPSSLQTHMYSH 305
                 69*******************99 PP

  == domain 2  score: 13.8 bits;  conditional E-value: 4.5e-05
   zf-C2H2_4   1 fkCpi..CgksFsskkaLlrHlkth 23 
                 + C++  Cg+ Fs  ++L+rH k h
  EEA21432.1 311 YACDVegCGRHFSVVSNLRRHKKVH 335
                 7899999*****99999****9998 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.0   1.3   9.8e-09   1.8e-05       2      23 ..     284     305 ..     283     306 .. 0.94

  Alignments for each domain:
  == domain 1  score: 25.0 bits;  conditional E-value: 9.8e-09
      zf-met   2 yCelCnvtfnsesqlksHlqGK 23 
                  C++C+++f+ +s+l++H+ ++
  EEA21432.1 284 KCKVCDKRFTRPSSLQTHMYSH 305
                 6******************997 PP

>> zf-C2H2_6  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.1      0.77   1.4e+03      18      25 ..      40      47 ..      39      49 .. 0.81
   2 !   22.0   2.4   6.4e-08   0.00012       2      24 ..     283     305 ..     282     308 .. 0.95
   3 ?    4.5   0.6     0.021        37       7      26 ..     318     337 ..     311     338 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.77
   zf-C2H2_6 18 ggHkksHr 25
                 gH +sH 
  EEA21432.1 40 AGHTSSHS 47
                59*****6 PP

  == domain 2  score: 22.0 bits;  conditional E-value: 6.4e-08
   zf-C2H2_6   2 heCsvCsksFpslqaLggHkksH 24 
                 h+C+vC+k+F    +L +H++sH
  EEA21432.1 283 HKCKVCDKRFTRPSSLQTHMYSH 305
                 9********************** PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.021
   zf-C2H2_6   7 CsksFpslqaLggHkksHrk 26 
                 C++ F+   +L+ Hkk H+ 
  EEA21432.1 318 CGRHFSVVSNLRRHKKVHKG 337
                 999999999*******9985 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   1.8   4.1e-07   0.00073       1      24 [.     282     305 ..     282     305 .. 0.94
   2 ?   -0.0   0.1      0.65   1.2e+03       7      22 ..     318     333 ..     318     333 .. 0.90

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 4.1e-07
                  ECBBTTTTBBBSSHHHHHCCTTSH CS
  zf-C2H2_jaz   1 qfYCvlCdKyFksenaldnHlkSK 24 
                  ++ C++CdK F   ++l++H+ S+
   EEA21432.1 282 KHKCKVCDKRFTRPSSLQTHMYSH 305
                  689******************996 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 0.65
                  TTBBBSSHHHHHCCTT CS
  zf-C2H2_jaz   7 CdKyFksenaldnHlk 22 
                  C ++F+  ++l+ H+k
   EEA21432.1 318 CGRHFSVVSNLRRHKK 333
                  999**99999999986 PP

>> zf-C2HC_2  zinc-finger of a C2HC-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.3    0.0082        15       4      20 ..     284     301 ..     282     304 .. 0.92
   2 ?    7.9   0.4    0.0016       2.9       7      23 ..     317     334 ..     316     334 .. 0.91

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0082
   zf-C2HC_2   4 pCpkCgRsF.npdrlekH 20 
                 +C+ C  +F  p++l+ H
  EEA21432.1 284 KCKVCDKRFtRPSSLQTH 301
                 8**************988 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0016
   zf-C2HC_2   7 kCgRsF.npdrlekHepv 23 
                 +CgR+F  ++ l +H++v
  EEA21432.1 317 GCGRHFsVVSNLRRHKKV 334
                 7*****99*******997 PP

>> zf-C2H2_2  C2H2 type zinc-finger (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   1.3   5.9e-05      0.11      44      73 ..     276     305 ..     266     314 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 5.9e-05
   zf-C2H2_2  44 rekieekleClyCekefkslealreHmkkk 73 
                  ++ ++k++C +C+k+f+  ++l++Hm ++
  EEA21432.1 276 PSNAQKKHKCKVCDKRFTRPSSLQTHMYSH 305
                 5566789********************875 PP

>> Actin_micro  Putative actin-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00019      0.35     210     246 ..     267     304 ..     246     335 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00019
  Actin_micro 210 fvdefrkleelkekkefsCkvCdvkfev.ekiseHllk 246
                  +  +f++  + + +k+ +CkvCd +f+  ++++ H+ +
   EEA21432.1 267 MMGQFSSKMPSNAQKKHKCKVCDKRFTRpSSLQTHMYS 304
                  566799999999***********************975 PP

>> zf-C2H2_11  zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   0.8    0.0037       6.6       5      24 ..     283     302 ..     280     303 .. 0.93
   2 ?    6.5   0.8    0.0039         7      10      28 ..     318     335 ..     316     336 .. 0.86

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.0037
  zf-C2H2_11   5 cqCleCGlcftSqlsLsRHl 24 
                 ++C  C   ft   sL+ H+
  EEA21432.1 283 HKCKVCDKRFTRPSSLQTHM 302
                 79999*9************9 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0039
  zf-C2H2_11  10 CGlcftSqlsLsRHlfIvH 28 
                 CG+ f+    L+RH   vH
  EEA21432.1 318 CGRHFSVVSNLRRHKK-VH 335
                 **************75.45 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (348 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       522  (0.0291148); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.47
# Mc/sec: 2239.12
//
Query:       EEA21433.1  [L=95]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (95 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       286  (0.0159518); expected 358.6 (0.02)
Passed bias filter:                      156  (0.00870099); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.34u 0.28s 00:00:00.62 Elapsed: 00:00:00.41
# Mc/sec: 703.26
//
Query:       EEA21434.1  [L=429]
Description: integral membrane protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.031   14.9   1.2      0.031   14.9   1.2    2.4  2  Phage_holin_4_2  Mycobacterial 4 TMS phage holin, superfamily


Domain annotation for each model (and alignments):
>> Phage_holin_4_2  Mycobacterial 4 TMS phage holin, superfamily IV
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   1.2   1.8e-06     0.031      56     103 ..     135     187 ..     116     189 .. 0.82
   2 ?   -1.1   1.6      0.17     3e+03      62      75 ..     315     335 ..     262     371 .. 0.54

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.8e-06
  Phage_holin_4_2  56 pltiltlGlftlvinalmlllaa.....alvsg.fevdgfwsallgaliisvvs 103
                        ti+tlG  ++vina+ ++l        +  g + v+g +sa++ga i  + s
       EEA21434.1 135 VGTIFTLGSAVWVINAFFVWLPLqkpstEFP-GeVDVAGGISAFIGATIFEIGS 187
                      4499*****************9745553343.36**************988765 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.17
  Phage_holin_4_2  62 l.......Glftlvinalmll 75 
                      +       G f +v++++++ 
       EEA21434.1 315 VywvpqmvGGFCFVLSGFLFT 335
                      033333334455666655555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (429 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       360  (0.0200792); expected 358.6 (0.02)
Passed bias filter:                      253  (0.0141112); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.48
# Mc/sec: 2701.13
//
Query:       EEA21435.1  [L=1243]
Description: urea amidolyase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.1e-78  262.6   0.0    7.7e-78  261.8   0.0    1.5  1  CT_A_B           Carboxyltransferase domain, subdomain A and 
      1e-55  188.5   0.0    2.4e-55  187.3   0.0    1.6  1  CPSase_L_D2      Carbamoyl-phosphate synthase L chain, ATP bi
    1.5e-39  135.0   0.2    7.1e-39  132.8   0.1    2.2  2  Biotin_carb_N    Biotin carboxylase, N-terminal domain
    1.8e-29  102.0   0.0    3.6e-29  101.0   0.0    1.5  1  Biotin_carb_C    Biotin carboxylase C-terminal domain
    2.1e-20   73.3   0.0    4.3e-20   72.3   0.0    1.5  1  CT_C_D           Carboxyltransferase domain, subdomain C and 
    3.9e-10   39.4   1.3    1.3e-09   37.7   1.3    2.0  1  Biotin_lipoyl    Biotin-requiring enzyme
    4.8e-09   36.0   0.0    9.7e-09   35.1   0.0    1.4  1  Dala_Dala_lig_C  D-ala D-ala ligase C-terminus
     0.0048   16.4   0.0      0.011   15.2   0.0    1.6  1  ATP-grasp_5      ATP-grasp domain
  ------ inclusion threshold ------
      0.013   15.1   0.0      0.031   13.8   0.0    1.6  1  ATP-grasp        ATP-grasp domain
      0.028   14.2   1.6        1.9    8.4   0.1    3.3  3  Biotin_lipoyl_2  Biotin-lipoyl like


Domain annotation for each model (and alignments):
>> CT_A_B  Carboxyltransferase domain, subdomain A and B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  261.8   0.0   4.3e-81   7.7e-78       2     263 ..     490     762 ..     489     763 .. 0.97

  Alignments for each domain:
  == domain 1  score: 261.8 bits;  conditional E-value: 4.3e-81
                 T----S-SSHHHHHHHHHHTTS-TTS-EEEEESC-EEEEESS-EEEEEEESCEEEEETTEEE-SSCEEEE-TT-EEEEEEESSECEEEEEETT-B.E-- CS
      CT_A_B   2 GvprsGamDrlalrlANrlvgNeegaaaLEitlggpelrfeedavvavtGadleatldgepvplwepvevkaGdvLklgaakaGlraYLavaGgl.dvp 99 
                 G+ ++G+mD+ a+++AN+lvgNe g +aLEitl+gpel f +dav++++G +++a+ldg+++p+w++v+++aG++Lk+g+++a +r+YLa+ Ggl +v 
  EEA21435.1 490 GFGHAGPMDPIAFQAANLLVGNEVGIEALEITLTGPELLFLGDAVISLCGPPIPAELDGKEMPQWTRVRIRAGQRLKIGKMAANCRVYLAIYGGLlNVS 588
                 999*******************************************************************************************98*** PP

                 -BTTB-S-BTTTTBSTTTTS---TT-EEEBSSSTT--S-C..BGGCS---SSCSEEEEEEEE-TTG.CCB-HHHHHHHHHS-EEEECEECSSEEEE... CS
      CT_A_B 100 evlgSrStdllaglGgleGraLkagdvLplgeaaaaaaaka.keleaaapeeseeeevrvvpGpqa.dlfteealeallssewtvsaesdRmGvrL... 193
                 +++gS+St+ + ++Gg++Gr+L+agd L++ e+++ +++ + + +++ +p+++++++++++pGp +  +++++++e++++++wt+s+++ R G+rL   
  EEA21435.1 589 KWFGSKSTNPMVNVGGYQGRPLRAGDFLSIVESSHLPEDVSvSIPQTLRPQYTSDWTIQIMPGPYEtGYLSTRDIEMFFAETWTISHNAARGGIRLigp 687
                 *******************************999999988789999******************9989****************************999 PP

                 .......ES.GG.SSCS.TEEEEEE--TTEEEE-CTTEEEEE-TTS-SEEEEEEEEEE-GGGHHHHTT--TTSEEEEE CS
      CT_A_B 194 .......dG.eaglerkesellsegvvlGaiqvppdgqpivllaDhqttGGYpkiatvisadldklaQlrpgdkvrFe 263
                        dG e g ++  s+++++g++lG +++ ++++p+++  D++  GG+ +  tvi+ d++kl+Qlr+gdkv+F+
  EEA21435.1 688 rpefgrsDGgEGGAHP--SNVIEYGYPLGGLNW-TGDEPVIFPVDCPDFGGFICSLTVIKGDIWKLGQLRAGDKVKFH 762
                 9999998776777888..8**************.*******************************************7 PP

>> CPSase_L_D2  Carbamoyl-phosphate synthase L chain, ATP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  187.3   0.0   1.4e-58   2.4e-55       2     203 ..     117     321 ..     117     326 .. 0.97

  Alignments for each domain:
  == domain 1  score: 187.3 bits;  conditional E-value: 1.4e-58
                  HHHHHHHHHHTT-BBSSEECSSBSSHHHHHHHHHHH-SSEEEEETTCCTTTTEEEESSHHHHHHHHHHHHHHHHHHHSTS-EEEEE--SSSEEEEEEE CS
  CPSase_L_D2   2 kesakealkkinvpvvpssaapvetleealaiakeigyPviikaafglGGkGmrvarneeelaelvkkalaeakaafgnkqvlvekslkgpkeiEvev 99 
                  k++a+e++ +++vpvvp++++  e++e a a+a ++gyPv++ka++g+GG G   + ne+e++e +++ ++ a++ f n+ v++e++    ++iEv+v
   EEA21435.1 117 KHTARELAVAAGVPVVPGTQGLLEDEEAAAAAATRLGYPVMLKATAGGGGMGLLACANEAEVRENFNTVISRASSLFKNAGVFLERYYPDSHHIEVQV 214
                  67899999****************************************************************************************** PP

                  EEETTS-EEEEEEEEECCECTCCCCEEEES-SS--HH...HHHHHHHHHHHHHHHHT-EEEEEEEEEEETTTTEEEEEEEESS--CCHHHHHHHHS-- CS
  CPSase_L_D2 100 lrDakgnvitvcerenslqlrtqkvievAPsqtLtde...erqalreaavkvvrevgvvgagtveflldpkskeyyviEvNtRlsvesalaekaTGld 194
                      +g +i v+ere+s+q+r+qkvie+ Ps++++++    rq+l + av++++++++ +agtve+l+d ++++++++E+NtRl+ve+ ++e+   +d
   EEA21435.1 215 FGNGQGKAISVGERECSIQRRHQKVIEECPSPFVSQRypdLRQKLTQCAVRLAEDIKYGSAGTVEYLVDDHTGDFFFLEMNTRLQVEHGITEMCYNVD 312
                  **********************************98533379******************************************************** PP

                  HHHHHHHHH CS
  CPSase_L_D2 195 lvkeaakia 203
                  lv+ +++ a
   EEA21435.1 313 LVELMLRQA 321
                  *****9977 PP

>> Biotin_carb_N  Biotin carboxylase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.8   0.1     4e-42   7.1e-39       3     110 .]       5     111 ..       3     111 .. 0.97
   2 ?   -1.0   0.0       1.4   2.5e+03      84     108 ..     666     690 ..     665     691 .. 0.91

  Alignments for each domain:
  == domain 1  score: 132.8 bits;  conditional E-value: 4e-42
                    -EEEE---HHHHHHHHHHHHHTT-EEEEEEEGGGTTSHHHHHSSEEEEEESSTTCCGGG-HHHHHHHHHHTT-SEEE--SSTTTT-HHHHHHHHHT CS
  Biotin_carb_N   3 kkvlianrGeiAvriiravrelgietvavyseedanslhvreadeavelgpasasesYlniekivkaakesgadavhpGyGflsEnaefaeaveea 98 
                    k++l+anrGeiA+r+i+a+++lgi+t+a+y+++d +s+hvr+ad+av l+ ++a+++Y++ ++i+++ak++ga+a+ pGyGflsEn++fa++ ++a
     EEA21435.1   5 KTILVANRGEIACRLIKAAQKLGIRTIAIYTQPDCESEHVRLADTAVLLQ-GEARAAYIDGDQIIQVAKDNGAQAIIPGYGFLSENTNFARSASAA 99 
                    89***********************************************6.88899**************************************** PP

                    T-EESSS-HHHH CS
  Biotin_carb_N  99 givfiGPsaeal 110
                    g+vf+GPs+ea+
     EEA21435.1 100 GLVFVGPSPEAI 111
                    *********987 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 1.4
                    TTTT-HHHHHHHHHTT-EESSS-HH CS
  Biotin_carb_N  84 flsEnaefaeaveeagivfiGPsae 108
                    f++E  + +++ ++ gi  iGP++e
     EEA21435.1 666 FFAETWTISHNAARGGIRLIGPRPE 690
                    889999999999**********987 PP

>> Biotin_carb_C  Biotin carboxylase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.0   0.0     2e-32   3.6e-29       1     107 [.     352     458 ..     352     459 .. 0.99

  Alignments for each domain:
  == domain 1  score: 101.0 bits;  conditional E-value: 2e-32
                    EEEEESEETTTTTEE--CE-SEEE---STTEEEEE---TT-EE-TTS-SEEEEEEEEESSHHHHHHHHHHHHHT-EEESS-BSHHHHHHHHH-HHH CS
  Biotin_carb_C   1 eaRinaEdpeknflpssGkvtelelpegpgvRvdsgveegsevspyyDsllaKlivhgetreealarlrraLaelrieGvktnieflrailedeef 96 
                    eaR++aE+p++n +ps+G +++++l + +g Rvd++v+ g  vs++yD+llaK++ hg+tre+a+a+++++L++  i G + n+ fl ai+++ +f
     EEA21435.1 352 EARVYAENPARNYAPSPGLLQQVSLYTPEGARVDTWVRGGIVVSAEYDPLLAKVMYHGSTREAAVATMEEILSKSSICGPPINLGFLLAIIQSGDF 447
                    89********************************************************************************************** PP

                    HHT---TTTCC CS
  Biotin_carb_C  97 akgeldtkfle 107
                    ++g++ tkfl+
     EEA21435.1 448 KRGNTITKFLD 458
                    *********98 PP

>> CT_C_D  Carboxyltransferase domain, subdomain C and D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.3   0.0   2.4e-23   4.3e-20       3     189 ..     829    1047 ..     827    1058 .. 0.92

  Alignments for each domain:
  == domain 1  score: 72.3 bits;  conditional E-value: 2.4e-23
                  EEEETTTEEEEEE-SS.--HHHHHHHHHHHHHHHT...........STTECEEEE-SSEEEEEESCCCCHHHHHH.HHHHHHHH...---------E CS
      CT_C_D    3 irplGdeallvefgee.isealskrvlalaaalraka.........lpgvvelvpayrsllvefdpealdaaellaalkallee..aeeeaaeesrl 87  
                  +r+ +d++llv++g+   +++ + r++al+++l+++            ++ ++v   +sl + +d  al++a+ll++l a++++  +  +a+ ++r+
  EEA21435.1  829 YRAGADDYLLVDYGNGcSDLNYKCRATALSRQLQNRSglvsaniknGGAIFNMVGCGNSLAICYDGLALSQADLLNELIAIEDTlgDMRSAKFPNRH 925 
                  678889999****98746668888999999999998888877766677899*******************************9999999999***** PP

                  EEEEEEESTTT-T...................THHHHHHHHTS-HHHHHHHHHHS-EEEEEE-SSTT-EEE----GG..G-----SS--S-B-TTEE CS
      CT_C_D   88 veipvcYdgevgp...................DLeevaelnglsveevirlhtaaeyrvaflGfapGfaylggldpr..lavpRrasPrtrvpagsV 163 
                  +++p+++ ++  +                    L+++ae ng++ ee+ ++  + +  + ++Gf+  ++   + dpr  ++ p+ +++rt +p+g+V
  EEA21435.1  926 FKLPLTFRHKKLEdamerymanqrplasylpdPLAFLAENNGMTIEELKTMFLTLQSVIIGVGFFMALPQSMPTDPRyrIRSPKMNPSRTYTPEGTV 1022
                  ********88888******************99********************************************9999**************** PP

                  EEETTEEEEE-S-B---SEEEEEE-S CS
      CT_C_D  164 giageqtgiyplesPGGWqliGrTpl 189 
                    +g+  +iyp++ PGG+   G T +
  EEA21435.1 1023 SWGGSAIAIYPVDCPGGYMPTGMT-I 1047
                  ******************999988.4 PP

>> Biotin_lipoyl  Biotin-requiring enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.7   1.3   7.5e-13   1.3e-09      15      71 ..    1177    1237 ..    1169    1239 .. 0.90

  Alignments for each domain:
  == domain 1  score: 37.7 bits;  conditional E-value: 7.5e-13
                     ..ECSESSSTTCEE-TTSEEEEEECTTEEEEEEBSS..SE.EEEEESSTTTEEE-TTCEEE CS
  Biotin_lipoyl   15 g.vvevlvkvGdkVkagqvlaeveamKmemeieapk..aG.vvkeilvkeGdtvevgdlla 71  
                     + v++vlv++Gd+ +ag ++ ++eamKme+ + a++  aG +v+++lvk Gd++e+g +++
     EEA21435.1 1177 AnVWKVLVQEGDELQAGKIVSILEAMKMEINVLADShlAGaTVAKVLVKPGDSIESGRPVI 1237
                     3499****************************9998788878***************9986 PP

>> Dala_Dala_lig_C  D-ala D-ala ligase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.1   0.0   5.4e-12   9.7e-09      23     174 ..     140     296 ..     121     314 .. 0.83

  Alignments for each domain:
  == domain 1  score: 35.1 bits;  conditional E-value: 5.4e-12
                      -H-HHHHHHHHHC-SSEEEEESSSSTTTTEEEESSGGGHHHHHHHHHT......T-SCEEEEE--.ESEEEEEEEEETSSCEEEEEEEEE-SSS CS
  Dala_Dala_lig_C  23 ekkellekveeelgypvfVKpareGSSvGvskveseeelkeaieeafk......ydekvlvEeai.egreievavlgneklevsevgeivvkkg 109
                      e++e  ++  ++lgypv+ K+   G  +G+ ++ +e+e++e +++ ++      +++ v+ E++  + + iev v gn++ ++ +vge+  +  
       EEA21435.1 140 EDEEAAAAAATRLGYPVMLKATAGGGGMGLLACANEAEVRENFNTVISrasslfKNAGVFLERYYpDSHHIEVQVFGNGQGKAISVGERECS-- 231
                      4457788999**********************99998887766544331111225778*******9**********************9775.. PP

                      SS-HHHHHC.TT-EEESS----HHHHHHHHHHHHHHHHHTT--SEEEEEEEE.ETTTEEEEEEEES CS
  Dala_Dala_lig_C 110 fydyeakysddkaqlevpaklekeveekiqelalkaykaldlrGlaRvDffl.teegeivlnEvNt 174
                      + + ++k + ++    +  +  ++ ++k++++a++  + ++    + v +++ +++g++++ E+Nt
       EEA21435.1 232 IQRRHQKVI-EECPSPFVSQRYPDLRQKLTQCAVRLAEDIKYGSAGTVEYLVdDHTGDFFFLEMNT 296
                      668899998.6677777778888999**************************8899*********9 PP

>> ATP-grasp_5  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   6.3e-06     0.011      12      55 ..     117     162 ..     113     216 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 6.3e-06
  ATP-grasp_5  12 eaeakelleaygipvvetrl..assaeeaveaaeeigypvvlKivs 55 
                  ++ a+el  a g+pvv+      +++e+a++aa ++gypv lK + 
   EEA21435.1 117 KHTARELAVAAGVPVVPGTQglLEDEEAAAAAATRLGYPVMLKATA 162
                  5889************987656*********************975 PP

>> ATP-grasp  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   1.7e-05     0.031      14     155 ..     139     293 ..     127     299 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.7e-05
                 ECCHHHHHHHHHHH-SCEEEEESSS-CTTTTEEEECTCCGHHCHHHHC........GTTCEEEEE----SEEEEEEEEEETTC-EEE--EEE...EEEE CS
   ATP-grasp  14 veskeeleeaaeelglpvvvKarrlgydGkGqsvvrseedleqaleal........keekvivEefvpfekElsvlvvrsaeGetafypvve...tvqe 101
                 +e++e++ +aa++lg+pv++K ++ g  G G   + +e+++++ ++++        k+  v +E + p +  + v v  + +G+  ++   e   + ++
  EEA21435.1 139 LEDEEAAAAAATRLGYPVMLK-ATAGGGGMGLLACANEAEVRENFNTVisrasslfKNAGVFLERYYPDSHHIEVQVFGNGQGKAISVGEREcsiQRRH 236
                 688889999************.89999***************999998899999999999999999999999999999999998665533221113333 PP

                 TTEEEEEEECEE-SCH...HHHHHHHHHHHHHHHHTSSEEEEEEEEEE.TTCTEEEEE CS
   ATP-grasp 102 dgilrlsvapaevsek...aqkkaeeiakkiveeLggvGvfavElFvl.edgellvnE 155
                 +++++++  p   + +     +k +++a +++e + +    +vE  v  ++g+ ++ E
  EEA21435.1 237 QKVIEECPSPFVSQ-RypdLRQKLTQCAVRLAEDIKYGSAGTVEYLVDdHTGDFFFLE 293
                 44555555554222.1243677788888888888887777777776653344455555 PP

>> Biotin_lipoyl_2  Biotin-lipoyl like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       2.2   3.9e+03      31      47 ..    1076    1092 ..    1076    1093 .. 0.87
   2 ?    8.4   0.1     0.001       1.9       5      35 ..    1171    1201 ..    1166    1211 .. 0.85
   3 ?    3.1   0.0     0.049        88       9      27 ..    1214    1233 ..    1210    1234 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 2.2
  Biotin_lipoyl_2   31 aelDsralqlalaqaea 47  
                       +e D ++++l++a  +a
       EEA21435.1 1076 YEVDEKEYDLKVAEFKA 1092
                       589*********99888 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.001
  Biotin_lipoyl_2    5 IaapvsGrVaqlnVkdGqrVkaGdvLaelDs 35  
                       I apv++ V +++V++G++ +aG +  +l+ 
       EEA21435.1 1171 IEAPVNANVWKVLVQEGDELQAGKIVSILEA 1201
                       89*********************88777765 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.049
  Biotin_lipoyl_2    9 vsG.rVaqlnVkdGqrVkaG 27  
                       ++G +Va+++Vk G+ ++ G
       EEA21435.1 1214 LAGaTVAKVLVKPGDSIESG 1233
                       6788***********98766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1243 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       528  (0.0294495); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.82u 0.31s 00:00:01.12 Elapsed: 00:00:00.47
# Mc/sec: 7930.94
//
Query:       EEA21436.1  [L=688]
Description: sodium/proline symporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-14   53.5  30.3    2.8e-14   52.8  30.3    1.3  1  SSF       Sodium:solute symporter family


Domain annotation for each model (and alignments):
>> SSF  Sodium:solute symporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.8  30.3   1.6e-18   2.8e-14       2     406 .]      55     470 ..      54     470 .. 0.80

  Alignments for each domain:
  == domain 1  score: 52.8 bits;  conditional E-value: 1.6e-18
         SSF   2 flagrsltgfvlglslaasnisaasfvGlaGavaasGlav.vllelgalllvlllllllaerlr.nagalTlpdylskRfkgkrilvylsalslllvit 98 
                 ++a  s+    ++ ++ +s   a  ++     ++ +G+++ ++++ ga + +ll  +  +e  r   +a T+ ++++ R+++     +l  l + ++ +
  EEA21436.1  55 MTAKHSVKAGLTASAVVSSWTIATTLLTSTTYGYSYGVSGpFWYAAGACVQILLFSVAAVELKRkAPNAQTFLQVIKVRYGSAV--HILFTLYSGVYQI 151
                 566666666677788888888899999999*******987478999999998888877777777467**************998..6777777778888 PP

         SSF  99 lklsvdlvggaklielalGlnyetavlllaaltalYtviGGllAvvytdtiqavlmlvgal..illiivllevG.gleslveklkeaapkv..vdlltp 192
                 +     lvgg +++  + G n  +   l+ + +++Yt++GG+ A+  td + +vl+ +  l  + ++++ ++++ +   + e l+eaa+    + + ++
  EEA21436.1 152 ITTVNLLVGGSAIFAAVTGTNRDAICYLFPIGVVIYTLMGGIKATFITDWVHTVLIYIIMLvsLFVFYTTSDIAgSPTRVWELLQEAATLHpvAGNANG 250
                 8888899****************9999**************************9864433300344455566663555566666666664453444444 PP

         SSF 193 dslkllrdpltals..lwlglvlGvaglphilvRflaakdakailkgvlkltivlilvligmisiilfaiklagavp......kavgtevgvsniaype 283
                 +   ++r+   + +  + +g ++   +     ++ +a +   + l  ++ ++ ++ + ++++ + +l a++l    p      + + +  ++s +a+p 
  EEA21436.1 251 QY-LTMRSEEGGYVglVFIGAGFAACVDSQLFQKAIASDPRTTSLGYIIGGLSWFTIPFVLASTYGLAAAALEHL-PswptypNRMNAYETASGLAMPY 347
                 44.3555554443311235556666666888999998877766666666789*******9999****99998766.4466777999999********** PP

         SSF 284 LvvkllpnllaGlllavmlAaimstltslllsassaftkDlYkkirrkasakekelvgvsriivlvvislaillavqeeqkg..vlklvelafaglasa 380
                  +++l++n+ a  +l +++ a+ s ++s ++++ +++t  +Y++ ++   a+ ++l+++s  i++  +     +av +++ g  v +l+ ++   + sa
  EEA21436.1 348 AAIALMGNGGAVAVLLMIFMAVTSAMSSETVATTALVTYNIYQAYIKPD-ATGRQLLYFSHFITVGFAIFCSSIAVAFNHGGfsVGFLITAIGIFVDSA 445
                 ********9999999999999***************************9.9************999999999999999999887888998888888888 PP

         SSF 381 vlavillalfwkrvneqGAlagliiG 406
                 ++++   +++w +  +  A++  +iG
  EEA21436.1 446 IVPM-ACTIMWRKQSRIAAFVVPVIG 470
                 8876.679*****9999998876665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (688 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       882  (0.049194); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.71u 0.30s 00:00:01.01 Elapsed: 00:00:00.48
# Mc/sec: 4274.44
//
Query:       EEA21437.1  [L=253]
Description: lactam utilization protein LamB [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.2e-85  287.0   0.1    1.4e-85  286.8   0.1    1.0  1  LamB_YcsF  LamB/YcsF family


Domain annotation for each model (and alignments):
>> LamB_YcsF  LamB/YcsF family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  286.8   0.1   7.8e-90   1.4e-85       3     238 ..      10     244 ..       8     245 .. 0.98

  Alignments for each domain:
  == domain 1  score: 286.8 bits;  conditional E-value: 7.8e-90
                 EEEEE---BTTB--S-HHHHCCC-SEEEEE-SSSS--HHHHHHHHHHHHHTT-EEEEE---S-TTTTT-S-----HHHHHHHHHHHHHHHHHHHHHTT- CS
   LamB_YcsF   3 lnaDlGEsfgawklgdDeallplvtsaNiACGfHaGdpevmrktvelakekgVaiGAhpgypDlegFGRremelspeelealvlyQigaLkafakaegv 101
                 +n+D+GE++g++ +g D++llp++++aN+ACGfHaGdp +m++tv+l+k++ V+iGAhpg+pD +gFGRrem+lspee +a v+yQigaLkaf++++gv
  EEA21437.1  10 INVDMGEAYGNYVCGPDKELLPMIDHANVACGFHAGDPLIMDETVALCKAHRVKIGAHPGLPDIQGFGRREMKLSPEEHTANVVYQIGALKAFLDRHGV 108
                 8************************************************************************************************** PP

                 ---EE---HHHHHHHHH-HHHHHHHHHHHHHH-TT.TEEEETTSHHHHHHHHCT--EEEEEETTB-B-TTSSB--TTSTTSB---HHHHHHHHHHHHHT CS
   LamB_YcsF 102 klshvkpHGaLynqaakdeelaeavveavkaldpelillglagseleeaaeeaglkvvaevfaDraYeadgslvprsqpgaviedpeevaervlklvee 200
                 +++hvkpHG Ly ++++d e+a+av +av +    + ++glag+++e+aa+eagl+++ae+f D +Y+adg+l+  +++     + e+v ++v k ++e
  EEA21437.1 109 EMHHVKPHGILYGMMVRDIEVARAVWAAVPKG---MRVFGLAGTHMETAANEAGLEFWAEYFGDVNYRADGTLIVDRKK--KPWKIEDVKKHVAKQLQE 202
                 ****************************9976...89*************************************98888..68999************* PP

                 SEEEBTTSSEEE---S....EEEE-SSSHHHHHCHCCCCHHH CS
   LamB_YcsF 201 gkvtavdgeevelkad....sicvHgDtpeavelaravreal 238
                 +kv a++geev+l +     +ic+H+D+p++ve+++a+re++
  EEA21437.1 203 SKVVAITGEEVDLPVAdypiTICCHSDSPGCVEIVTATREVV 244
                 *************9888999*******************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (253 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       555  (0.0309554); expected 358.6 (0.02)
Passed bias filter:                      503  (0.0280551); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.25s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 1766.23
//
Query:       EEA21438.1  [L=611]
Description: flavin-containing amine oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.3e-58  198.6   0.0    2.7e-58  198.4   0.0    1.1  1  Amino_oxidase  Flavin containing amine oxidoreductase
    8.9e-14   51.5   0.2    2.3e-13   50.1   0.2    1.8  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
    2.8e-13   49.9   0.0      6e-13   48.9   0.0    1.5  1  Ribonuc_L-PSP  Endoribonuclease L-PSP
    1.1e-08   34.6   1.2    1.7e-08   34.0   1.2    1.3  1  FAD_binding_2  FAD binding domain
    3.5e-08   33.2   0.2    4.8e-08   32.8   0.2    1.2  1  FAD_oxidored   FAD dependent oxidoreductase
    9.6e-07   28.7   0.1    1.8e-06   27.8   0.1    1.5  1  DAO            FAD dependent oxidoreductase
    4.8e-06   26.0   0.1    8.4e-06   25.2   0.1    1.4  1  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    5.1e-06   26.0   0.2    8.1e-06   25.3   0.2    1.3  1  FAD_binding_3  FAD binding domain
    1.7e-05   24.2   0.1    3.4e-05   23.2   0.1    1.4  1  Thi4           Thi4 family
     0.0001   21.5   0.6    0.00024   20.3   0.6    1.6  2  Lycopene_cycl  Lycopene cyclase protein
    0.00011   21.0   0.2    0.00023   20.0   0.2    1.5  1  HI0933_like    HI0933-like protein
     0.0004   19.7   1.9    0.00042   19.7   0.1    1.8  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
      0.001   18.2   0.4     0.0017   17.5   0.4    1.3  1  GIDA           Glucose inhibited division protein A
      0.001   19.6   0.1     0.0025   18.4   0.1    1.6  1  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
      0.019   14.7   0.0      0.032   13.9   0.0    1.3  1  DUF1999        Protein of unknown function (DUF1999)
      0.026   13.8   0.3      0.061   12.6   0.3    1.6  1  AlaDh_PNT_C    Alanine dehydrogenase/PNT, C-terminal domain
       0.46   10.5   2.1        1.5    8.8   0.2    2.4  3  NAD_binding_9  FAD-NAD(P)-binding


Domain annotation for each model (and alignments):
>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  198.4   0.0   2.6e-61   2.7e-58       1     452 []     157     600 ..     157     600 .. 0.87

  Alignments for each domain:
  == domain 1  score: 198.4 bits;  conditional E-value: 2.6e-61
                    HHHHHHHHHHHHTTEEEEEEESSSSSBTTS-EEEET.T..EEEESS--EEET.TTHHHHHHHHHTTCCCCEEEESCCGCEEEEETTEECCTTEECH CS
  Amino_oxidase   1 laGLaaArqLlsaGfdVtvlEardrvGGRirtvrsd.G..ylielGamwftg.agnpllellkelgledslslpdpgapkrvlskggrefpgdlsp 92 
                    laGLaaA++L++aG+++ +lEardrvGG+ ++  +  G   +++lGa w++  +++ +++l+k++g e   +  + + ++ + +++g   ++++ +
     EEA21438.1 157 LAGLAAATELQRAGHSFMILEARDRVGGKTWSQALLdGeqGVVDLGAAWINStNQSKMYALAKKYGAEILEQ--NTTGKCVLQDADGNCSTFEYGD 250
                    79********************************9974669***************************9888..3334788889999999777777 PP

                    HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHH..HHHHHHHHHHHHHHHHHHCHTSTTTTCBHH CS
  Amino_oxidase  93 vpaewealleqgalsaellsleeklrlgleallqktldeldldskslaesleelgrrepgdvev..wdrliepelfaklefasglfagdpselsak 186
                    +p+ +++ +      ++  ++ +++++  + l  + ++  + ds ++++ l+++g+  +   ++  w+r ++    +     s+l++       ++
     EEA21438.1 251 LPK-FNTAIA-----KDVARIRDMVEADCQTLNPARPQNAEWDSVTFEAYLRSSGASAEALATAtvWTRAMLG---QDPKDISALYFL--TYCRSG 335
                    775.566666.....455566666666666666999********************9999877788******7...666667777776..66899* PP

                    HHTCCCCHHHHHTSCCCEETTHTHHHHHHHHHTTTTEEEETSEEEEEEEE..ETTCEEEEETTSTEEEESEEEE-S-HHHHHSSEEESCCSHHHHH CS
  Amino_oxidase 187 lalpllwelegfggslllprgGlsqlpealaeelrgldirlntrVkeikr..egdgvtvtledgevveaDaVvvTvplgvlkailfsPplpdekae 280
                      l + + +   gg++l++r G +     la++l+++++ l+t+V++i++   ++ + vt++++++++a++V+ Tvp +vlk+i f+P lp  k  
     EEA21438.1 336 GGLLQMRSDRLGGGQHLRIRQGTQLFSIGLAKDLPEGTVCLSTPVSSITQgnISSDIEVTTVNQKKFRARKVITTVPSPVLKTISFTPDLPSSKKL 431
                    **************************************************7655669*********************************999999 PP

                    HHHHSEEEEEEEEEEEESSGGSGCSTSECECECCCEEETTTEEEEECCECCCSTTTEEEEEEEEECHHHHHHHTTS-HHHHHHHHHHHHHHHHT.. CS
  Amino_oxidase 281 airnlgfgsvnkvilefdrkfwednalgqgvlvseltttlgeafissdfpsrappgkglvllvyvggdaaneleslsdeelvqavlrdLrklfg.. 374
                      ++  +g  +k+ + f+++fw +++   g + s + + +  + +ss      p+ k++ l+ +v+gd ++ ++ l  ee+  a+++++ +lf+  
     EEA21438.1 432 WSESSVYGYYTKAMMIFRTPFWVEKGY-CGLSQSFTGPAAVIRDTSSL-----PDQKHI-LTCFVAGDPGRVWAALATEEREMALVKQIGQLFNsk 520
                    999*********************873.22456666666666666644.....555555.**********************************99 PP

                    .GTSSTCSEEEEEECCTETTTSSSEEE.BTTHHHHHHHHHHCH.HCSTTEEE.SGGGCTTTTTSHHHHHHHHHHHHHHHH CS
  Amino_oxidase 375 .eevpepkatlvtrWhtdplargsysyvsvgpghedydplakp.egdprlffAGehtsreypgtvegAilSGlraAaril 452
                     e+  + ++++   W +dp+++      s +pg  d        e+ + l+fAG  t+ ++ g++egA++SG raAa+++
     EEA21438.1 521 vEASRDFVNMVTYEWISDPYSGWGCPCASLTPGVMDTLGGSGLrEPFGDLHFAGTETAVNWRGYMEGAVESGERAAAEVI 600
                    999999999************8888777887754444433333589********************************97 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.1   0.2   2.2e-16   2.3e-13       1      66 [.     152     219 ..     152     221 .. 0.90

  Alignments for each domain:
  == domain 1  score: 50.1 bits;  conditional E-value: 2.2e-16
                    EE--SHHHHHHHHHHHCCTEEEEEE-SSSSSSGGG-EECE.TT..CEECTS---EEETTHHHHCHHHHC CS
  NAD_binding_8   1 IvGaGlsGlvaAylLakagfdvlllekrdrlGGraasyev.pg..vrvdygahifhgsgyypnvrrllr 66 
                    IvGaGl+Gl+aA +L++ag++  +le+rdr+GG+  s  + +g   +vd+ga +++++ ++ ++ +l++
     EEA21438.1 152 IVGAGLAGLAAATELQRAGHSFMILEARDRVGGKTWSQALlDGeqGVVDLGAAWINST-NQSKMYALAK 219
                    9*************************************99955569***********7.4777777766 PP

>> Ribonuc_L-PSP  Endoribonuclease L-PSP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.9   0.0   5.7e-16     6e-13      17     120 ..      26     127 ..      13     128 .. 0.90

  Alignments for each domain:
  == domain 1  score: 48.9 bits;  conditional E-value: 5.7e-16
                    ETTEEEEEEE-SB-TTTSCB.-SSHHHHHHHHHHHHHHHHHHTT--GGGEEEEEEEESSGGG.HHHHHHHHHHHSSSSTS--EEEEEE-SBSG.GG CS
  Ribonuc_L-PSP  17 agnlvyvsGqlpldpetgelvegdveeqtrqalenlkavLaaagaslsdvVkvtvFladied.faevnevyaeafdelkeaParsaveVaaLp.kg 110
                    + +++yvsGq +++   g +v++d e q + al nl++++   g++++d++k+t ++++ +   ++  + ++++++ +  +Pa ++v Va+L+ +g
     EEA21438.1  26 NSEVLYVSGQPGST--RGGIVPTDYESQIHLALLNLRKIMIIGGVTVKDILKLTLLIVNYDPkQRKHARPLEKFLTGH--RPAITLVPVAQLAvPG 117
                    5679********98..6*****************************************99885677788888888888..5*************** PP

                    -SEEEEEEEE CS
  Ribonuc_L-PSP 111 akvEIeaiav 120
                    +++EI+a+++
     EEA21438.1 118 WLFEIDAVIA 127
                    ******9975 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.0   1.2   1.7e-11   1.7e-08       1      46 [.     149     193 ..     149     197 .. 0.92

  Alignments for each domain:
  == domain 1  score: 34.0 bits;  conditional E-value: 1.7e-11
                    SEEEE--SHHHHHHHHHHHHTTT-EEEEESSSGGGSGGGG--S-EE CS
  FAD_binding_2   1 DviViGsGlAGLaAAleaaeaGlkvavvekeqefggatawsqGgid 46 
                    Dv+++G+GlAGLaAA+e+++aG++ +++e  +++gg t wsq+ +d
     EEA21438.1 149 DVVIVGAGLAGLAAATELQRAGHSFMILEARDRVGGKT-WSQALLD 193
                    9********************************99876.8888765 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.8   0.2   4.5e-11   4.8e-08       1      46 [.     149     194 ..     149     308 .. 0.64

  Alignments for each domain:
  == domain 1  score: 32.8 bits;  conditional E-value: 4.5e-11
  FAD_oxidored   1 DvvVvGGgpaGvaAAiaAaraGakvlLveergvlGGlltsglvatd 46 
                   Dvv+vG+g+aG+aAA    raG + +++e r+++GG + s+++   
    EEA21438.1 149 DVVIVGAGLAGLAAATELQRAGHSFMILEARDRVGGKTWSQALLDG 194
                   9***********************************9988875433 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.1   1.7e-09   1.8e-06       1      41 [.     149     190 ..     149     315 .. 0.79

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 1.7e-09
                 EEEEECTSHHHHHHHHHHHHTT..EEEEESSSSTTSSGGGSSE CS
         DAO   1 dvviiGGGiiGlstAyeLarrg..VtllekgdiagsgaSgrns 41 
                 dvvi+G+G +Gl++A eL+r+g    +le++d++g g ++  +
  EEA21438.1 149 DVVIVGAGLAGLAAATELQRAGhsFMILEARDRVG-GKTWSQA 190
                 9*****************99999************.9888655 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   0.1   7.9e-09   8.4e-06       2      80 ..     149     227 ..     148     251 .. 0.67

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 7.9e-09
                  SEEEE--SHHHHHHHHHHHHHTS-EEEEETTHCHHHCSHHHHCHHHHHHHHHHHHHHHHHCHHHHCCCCHCCT.CEEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxx RF
  Pyr_redox_2   2 dvvviGgGpAGlaaaltlaqagakvtlvelegtclnggcllskallgvaedaeiasevvkklnqgielllgee.vvkidp 80 
                  dvv++G+G AGlaaa++l++ag+  +++ + +  ++g+ + +  l g ++  +  +  +++ nq+ ++ l+++ + +i +
   EEA21438.1 149 DVVIVGAGLAGLAAATELQRAGHSFMIL-EARDRVGGKTWSQALLDGEQGVVDLGAAWINSTNQSKMYALAKKyGAEILE 227
                  8***************************.788888998888888888777777666555556666333333333555553 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.3   0.2   7.7e-09   8.1e-06       2      34 ..     148     180 ..     147     190 .. 0.93

  Alignments for each domain:
  == domain 1  score: 25.3 bits;  conditional E-value: 7.7e-09
                    EEEEEE--SHHHHHHHHHHHHTTHHEEEEESSS CS
  FAD_binding_3   2 tdVlIVGaGpaGlmlallLseaGvrvvlvekrs 34 
                    +dV+IVGaG+aGl +a++L++aG + +++e r+
     EEA21438.1 148 VDVVIVGAGLAGLAAATELQRAGHSFMILEARD 180
                    79****************************986 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.2   0.1   3.3e-08   3.4e-05      18      59 ..     148     188 ..     140     196 .. 0.93

  Alignments for each domain:
  == domain 1  score: 23.2 bits;  conditional E-value: 3.3e-08
                 EEEEEE--SHHHHHHHHHHHHCTTS-EEEEESSSS--TTTTT CS
        Thi4  18 sDvvivGaGssGLtaayylakkpdlkvailersvspGGGawl 59 
                  DvvivGaG +GL+aa  l ++ +   +ile++  +GG +w 
  EEA21438.1 148 VDVVIVGAGLAGLAAATELQRA-GHSFMILEARDRVGGKTWS 188
                 6********************9.******************6 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.6   2.3e-07   0.00024       1      46 [.     149     189 ..     149     207 .. 0.90
   2 ?   -2.6   0.0       2.1   2.2e+03      93     141 ..     365     413 ..     357     421 .. 0.78

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 2.3e-07
  Lycopene_cycl   1 DvvviGaGpAglslAarlteakpglkvvlieaspsllfpnnyvWsd 46 
                    Dvv++GaG+Agl+ A +l  +++g + +++ea + +   + ++Ws 
     EEA21438.1 149 DVVIVGAGLAGLAAATEL--QRAGHSFMILEARDRV---GGKTWSQ 189
                    9*****************..************9999...7788986 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 2.1
  Lycopene_cycl  93 llerlvengvklleakvesveeeea.geslvvleggrkirarlvvdargl 141
                    l+++l+ +g   l+  v s+++ +  ++  v++ + +k rar v+   + 
     EEA21438.1 365 LAKDLP-EGTVCLSTPVSSITQGNIsSDIEVTTVNQKKFRARKVITTVPS 413
                    666777.56667788899999998877888999999999**999987764 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   0.2   2.2e-07   0.00023       2      38 ..     149     185 ..     148     189 .. 0.95

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 2.2e-07
                  SEEEE--SHHHHHHHHHHHHTT--EEEE-SSSSS-HH CS
  HI0933_like   2 dviviGgGaAGlmaAisaakrgkrVlllekakklgrK 38 
                  dv+++G+G AGl aA +++++g++ ++le+ +++g K
   EEA21438.1 149 DVVIVGAGLAGLAAATELQRAGHSFMILEARDRVGGK 185
                  8*********************************988 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.1     4e-07   0.00042       1      30 [.     151     179 ..     151     187 .. 0.90
   2 ?   -1.6   0.2       1.2   1.2e+03     100     130 ..     376     409 ..     372     411 .. 0.72

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 4e-07
  Pyr_redox_3   1 iIiGaGPaGlaaaielkkagledylilEkg 30 
                  +I+GaG aGlaaa+el++ag  +++ilE  
   EEA21438.1 151 VIVGAGLAGLAAATELQRAGH-SFMILEAR 179
                  7*******************9.8*****86 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 1.2
  Pyr_redox_3 100 lfeeVesvkk..edegfevetske.tyeAkkvii 130
                  l + V s+++   ++  ev+t ++ +++A+kvi 
   EEA21438.1 376 LSTPVSSITQgnISSDIEVTTVNQkKFRARKVIT 409
                  5678899998432567888886654999999995 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   0.4   1.6e-06    0.0017       1      30 [.     149     177 ..     149     197 .. 0.84

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 1.6e-06
                 CEEEE-SSHHHHHHHHHHHHTT--EEEEES CS
        GIDA   1 dviViGgGhAGceAAlaaarlGakvlLith 30 
                 dv+++G+G+AG++AA ++ r+G++ +++ +
  EEA21438.1 149 DVVIVGAGLAGLAAATELQRAGHSFMIL-E 177
                 79********************987766.4 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.1   2.3e-06    0.0025       2      40 ..     150     185 ..     149     196 .. 0.88

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 2.3e-06
                 EEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSSTTSSH CS
   Pyr_redox   2 vvvvGgGyiglElAgalaelgkkVtvversdkllrllDe 40 
                 vv+vG+G+ gl +A++l++ g++  ++e++d++    ++
  EEA21438.1 150 VVIVGAGLAGLAAATELQRAGHSFMILEARDRVG---GK 185
                 8*******************************98...44 PP

>> DUF1999  Protein of unknown function (DUF1999)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   3.1e-05     0.032      45      99 ..     160     215 ..     154     239 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 3.1e-05
     DUF1999  45 laaLkfyeRsehsfvae.eegelrGlvlaqsvWqGDrpivlvrrlllaeaadaeva 99 
                 laa    +R++hsf+    ++++ G   +q++  G++ +v + + ++++ ++++++
  EEA21438.1 160 LAAATELQRAGHSFMILeARDRVGGKTWSQALLDGEQGVVDLGAAWINSTNQSKMY 215
                 67777789******998689*********************999999998776665 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.3   5.8e-05     0.061      30      62 ..     149     181 ..     142     212 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 5.8e-05
                  EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHH CS
  AlaDh_PNT_C  30 kvlviGgGvaGlqAiatakglgakVtvlDvrpa 62 
                   v+++G+G aGl+A+   ++ g + ++l+ r +
   EEA21438.1 149 DVVIVGAGLAGLAAATELQRAGHSFMILEARDR 181
                  69*********************9999998876 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   0.2    0.0014       1.5       1      44 [.     151     189 ..     151     194 .. 0.82
   2 ?    0.0   0.0      0.72   7.6e+02      63      98 ..     285     318 ..     272     319 .. 0.82
   3 ?   -2.7   0.0       4.8   5.1e+03     122     152 ..     378     410 ..     366     411 .. 0.70

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0014
  NAD_binding_9   1 aivGaGprGlavlerLlarakkkspleitlfdpsep.gagrvwrt 44 
                    +ivGaG +Gla++++L +       ++ ++ + +   g g+ w++
     EEA21438.1 151 VIVGAGLAGLAAATELQRA-----GHSFMILEARDRvG-GKTWSQ 189
                    7**************9888.....47778888865536.888886 PP

  == domain 2  score: 0.0 bits;  conditional E-value: 0.72
  NAD_binding_9  63 tddpptfaeWlrergaleeaeeldpddfvpRalyGr 98 
                    + d+ tf+ +lr+ ga  +ae+l   ++ +Ra++G+
     EEA21438.1 285 EWDSVTFEAYLRSSGA--SAEALATATVWTRAMLGQ 318
                    557799********97..457999999999999995 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 4.8
  NAD_binding_9 122 aevvdleera..dgqavlladgaslaadaVvLA 152
                    + v ++++ +  +  +v++ ++++++a++V+ +
     EEA21438.1 378 TPVSSITQGNisSDIEVTTVNQKKFRARKVITT 410
                    566667776632334888999999999999865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (611 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       408  (0.0227564); expected 358.6 (0.02)
Passed bias filter:                      383  (0.021362); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              17  [number of targets reported over threshold]
# CPU time: 0.63u 0.33s 00:00:00.96 Elapsed: 00:00:00.50
# Mc/sec: 3711.34
//
Query:       EEA21439.1  [L=486]
Description: succinate-semialdehyde dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   3.1e-163  543.6   0.0   3.8e-163  543.3   0.0    1.0  1  Aldedh    Aldehyde dehydrogenase family
  ------ inclusion threshold ------
      0.029   13.8   0.0       0.84    9.0   0.0    2.1  2  DUF1487   Protein of unknown function (DUF1487)


Domain annotation for each model (and alignments):
>> Aldedh  Aldehyde dehydrogenase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  543.3   0.0  4.3e-167  3.8e-163       6     462 .]      19     475 ..      14     475 .. 0.97

  Alignments for each domain:
  == domain 1  score: 543.3 bits;  conditional E-value: 4.3e-167
                 SSEEEEEETTTCEEEEEEE-B-HHHHHHHHHHHHHHHHHHTTS-HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH---HHHHHHHHHHHHHHHHHHHHHH CS
      Aldedh   6 setievinPatgeviakvpaataedvdaavaaAkeafkawaklpaeeRaeiLrkaadlleerkeelaeletletGkplaearaeveeaidvlryyaela 104
                 +et++v++Patg +i+++p++t++d++ a++aA+ af++w++ + +eR++iLr++ +l+ e+k++la+l+t e+Gk   +a++ev  a+++l+++ae+a
  EEA21439.1  19 KETFDVFDPATGLKIGSCPESTPADAQLAIDAAATAFPEWRSRSGRERSRILRRWYELVMENKDDLATLITFENGKAKGDASGEVLFAASFLEWFAEEA 117
                 378************************************************************************************************ PP

                 HHHSEEEEEE.CTTEEEEEEEEE-SEEEEEE-SSSCCHHHHHHHHHHHHTT-EEEEEE-TTSHHHHHHHHHHHHHTTS-TTSEEE--SS..TCCHHHHH CS
      Aldedh 105 eklegevlps.segklalvrrePlGvvgaItPWNfPlllaawklapalaaGNtvvlKPaeetplsalllaelfeeaglPkgvlnvvtgs..gsevgeal 200
                  +++g+ +p  s+ ++  v++eP+Gv+g+ItPWNfP+ ++++k+ palaaG+tvvlK   etp+sa +la l+++ag+P+gv+n++t      ++g+ l
  EEA21439.1 118 ARIYGDLIPHsSTAYRVSVVKEPIGVCGLITPWNFPAGMVTRKIGPALAAGCTVVLKSPGETPFSANALAVLAQQAGVPPGVINIITCLanTPQIGQLL 216
                 **********779*************************************************************************76422899***** PP

                 HH-TTESEEEEES-HHHHHHHHHHHHCTTSEEEEEE---EEEEE-TTSHHHHHHHHHHHHHHGGGGTSTTSEEEEEEEHHHHHHHHHHHHHHHHT--BS CS
      Aldedh 201 vehpevdkvsftGstevgrkiakaaaknlkrvtlElGGknplivledaDldkaveaivkgafgnaGQvCiaasrllvqesiydefveklveaakklkvg 299
                 +++  ++kvsftGst++gr +++++++++k+++lElGG++p+iv++daDld a++++v++ f  +GQ+C++a+r++v++ ++defv+ l+ea+++++vg
  EEA21439.1 217 CTSSIIRKVSFTGSTRIGRLLMAQSSSTIKKLSLELGGNAPFIVFDDADLDLAIREVVTAKFKGSGQTCVCANRIFVHDRVFDEFVQHLKEATSNFRVG 315
                 *************************************************************************************************** PP

                 -TTSTT-SB---SSHHHHHHHHHHHHHHHHTTSEEEE-TTE.SB-SSST.TEE--EEEES-TTTSHHHHS---SSEEEEEEESSHHHHHHHHHSSSEES CS
      Aldedh 300 dpldedtdvGPliseaqlekvekyveeakeegaklllGgereeaglekg.yfvePtvlanvtpdmriaqeEiFGPVlsvikfkdeeeaieiaNdteyGL 397
                 ++ +++t+ GPlis a++ekv ++v++a+++gak++ Gg   +++++ g +f+ePt+l++ +p  +i +eEiFGPV++v +f++e++++ +aNd+++GL
  EEA21439.1 316 SGHEPSTTHGPLISTAAVEKVARLVDDAVSRGAKVIAGG---KRRPDIGpCFYEPTILTDGDPGLSISREEIFGPVAVVHRFDSEKQVLTAANDCDVGL 411
                 ***************************************...44555555************************************************* PP

                 EEEEE-SBHHHHHHHHHHS-SSEEEESSSST--TTTSEB--CGGGEES-BSHHHHHHHTEEEEEE CS
      Aldedh 398 aagvftkdleraervaerleaGnvyiNdsttgaaealpfgGvkqSglGreggkegleeytevktv 462
                 aa++ft+dl+ra r++e+++ G+v iN+ ++++a   pfgG+kqSglGreg+k+gl++y+++ktv
  EEA21439.1 412 AAYLFTQDLNRATRLSEQIQSGMVAINCGSVSDAPV-PFGGIKQSGLGREGSKYGLDDYLQLKTV 475
                 ************************************.**************************98 PP

>> DUF1487  Protein of unknown function (DUF1487)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.0   9.4e-05      0.84       8      57 ..     258     309 ..     255     352 .. 0.84
   2 ?    2.4   0.0      0.01        89     119     175 ..     391     446 ..     382     450 .. 0.75

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 9.4e-05
     DUF1487   8 mvifedgDlnsalealveslkePfaegava..tvlveesirdefvervrskl 57 
                 +++f+d+Dl+ a++ +v +  +  ++  v    ++v++ + defv+ +++  
  EEA21439.1 258 FIVFDDADLDLAIREVVTAKFKGSGQTCVCanRIFVHDRVFDEFVQHLKEAT 309
                 59*************999887777777765236*************998765 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.01
     DUF1487 119 lhtFrnakEvvkllakeslkfasvsvwneklaavyelvarlnvdvftiNCakvslkp 175
                 +h F + k v   ++   + + + +++ + l  +  l +++++ +++iNC +vs  p
  EEA21439.1 391 VHRFDSEKQVLTAANDCDVGL-AAYLFTQDLNRATRLSEQIQSGMVAINCGSVSDAP 446
                 566666666655444444444.45899999********************9887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (486 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       346  (0.0192983); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 3105.18
//
Query:       EEA21440.1  [L=628]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.2e-19   68.1   0.3    4.2e-18   65.3   0.0    2.4  3  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0     0.071   1.3e+03     119     139 ..      46      67 ..      36      90 .. 0.77
   2 ?   -0.9   0.0     0.037   6.6e+02     116     136 ..     103     124 ..      86     138 .. 0.80
   3 !   65.3   0.0   2.4e-22   4.2e-18       2     182 ..     215     377 ..     214     440 .. 0.83

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.071
  Fungal_trans 119 vavr.larslgLhrnpsyvgkk 139
                   +a +  +rs+ L+r p y + +
    EEA21440.1  46 TAASsSRRSPPLNRAPIYTSAD 67 
                   4445599*******99998843 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.037
  Fungal_trans 116 hhgvavr.larslgLhrnpsyv 136
                   ++g+av+ l++ ++Lhr +++ 
    EEA21440.1 103 YVGTAVSnLVHLVRLHRASAHA 124
                   99***************88765 PP

  == domain 3  score: 65.3 bits;  conditional E-value: 2.4e-22
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLl 98 
                   d +f+++hp  p++  p f++ +    +sk +  + ll+ a+l  Ga+ ++ +   s   +      + + + ra++l+  +++ ++++++  q+ +
    EEA21440.1 215 DAYFKHIHPFHPVISMPEFMVAY----KSKDNPPPLLLFQAVLTAGAHACSHPLVASARHAV-----KTTLYRRASMLF--HMRHETDRVYLMQAAM 300
                   78*********************....555555555555***************99822222.....233344999999..*************999 PP

  Fungal_trans  99 llelyektssd.ralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqin 182
                   l+       ++ +++ ++++gva+r+   lg+hr+++          ++e   + rR+ww+aF+ +++ +l +Grp   ++ +++
    EEA21440.1 301 LFTRHIGDGDTvTTGPWYWSGVAIRIGCGLGMHRHSPIL-------PPIE-TSQYRRCWWSAFICEVFSSLETGRPCAVRAGDMD 377
                   999999998889**************************5.......4677.7777*********************855555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (628 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       383  (0.021362); expected 358.6 (0.02)
Passed bias filter:                      341  (0.0190195); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.39
# Mc/sec: 4891.38
//
Query:       EEA21441.1  [L=273]
Description: SAP domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-13   50.4   0.6    1.2e-13   50.4   0.6    1.8  2  SAP           SAP domain
    6.5e-06   25.9   0.4    6.5e-06   25.9   0.4    2.1  2  Tho1_MOS11_C  Tho1/MOS11 C-terminal domain


Domain annotation for each model (and alignments):
>> SAP  SAP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.4   0.6   1.4e-17   1.2e-13       1      35 []       5      39 ..       5      39 .. 0.97
   2 ?   -3.0   0.2      0.73   6.6e+03      11      17 ..     145     151 ..     142     153 .. 0.78

  Alignments for each domain:
  == domain 1  score: 50.4 bits;  conditional E-value: 1.4e-17
                HTT--HHHHHHHHHHTT--TTS-HHHHHHHHHHHH CS
         SAP  1 lskltVaeLKeeLkkrGLptsGkKaeLieRLkeyl 35
                ++k tVa+L+e+Lk rGL t+GkKaeLi+RL+e++
  EEA21441.1  5 YEKKTVAQLQEILKGRGLTTTGKKAELIARLQEAD 39
                8999*****************************86 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.73
                 HHHHHTT CS
         SAP  11 eeLkkrG 17 
                 eeL+kr 
  EEA21441.1 145 EELRKRK 151
                 6888885 PP

>> Tho1_MOS11_C  Tho1/MOS11 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.9   0.4   7.2e-10   6.5e-06      10      50 ..     145     188 ..     141     192 .. 0.82
   2 ?   -2.5   0.2      0.53   4.8e+03      17      23 ..     264     270 ..     254     272 .. 0.59

  Alignments for each domain:
  == domain 1  score: 25.9 bits;  conditional E-value: 7.2e-10
  Tho1_MOS11_C  10 elLekklkRakKFg....qeeeaidelekqleRieKFGvdlntql 50 
                   e+L k+++Ra+KFg    +++e+  e+ek l R+++FG  ++++l
    EEA21441.1 145 EELRKRKARAEKFGivaeTGSEE-TEAEKILDRAKRFGTGASNDL 188
                   89***********9554444445.99************9998887 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.53
  Tho1_MOS11_C  17 kRakKFg 23 
                   +R+++F+
    EEA21441.1 264 ARKNRFA 270
                   4556665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (273 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       538  (0.0300073); expected 358.6 (0.02)
Passed bias filter:                      267  (0.0148921); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.25s 00:00:00.67 Elapsed: 00:00:00.41
# Mc/sec: 2014.92
//
Query:       EEA21442.1  [L=1468]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    0.00098   19.7   0.0     0.0027   18.3   0.0    1.7  1  Methyltransf_11  Methyltransferase domain
  ------ inclusion threshold ------
      0.035   14.8   0.0       0.11   13.2   0.0    1.9  1  Methyltransf_25  Methyltransferase domain


Domain annotation for each model (and alignments):
>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0     3e-07    0.0027      49      94 ..    1222    1268 ..    1174    1270 .. 0.82

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 3e-07
                       TEECCCTSS-TT-EEEEEEES-CCC-.CCHHHHHHHHHHHEEEEEEE CS
  Methyltransf_11   49 vadaeklpfednsfDlvvssevlhhv.edpekalkeiaRvLkpgGll 94  
                         + + +pf+++ f ++v+++       +++++l+e++RvL+pgG+l
       EEA21442.1 1222 IINGTAFPFPKGFFSACVLRFPAASSeGRQRHILSECKRVLRPGGYL 1268
                       4566778**************666664899****************8 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   1.2e-05      0.11      54      97 .]    1224    1266 ..    1208    1266 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.2e-05
                       BCCGBSSSTTTEEEEEEESTGGGSSHHHHHHHHHHHHHHEEEEE CS
  Methyltransf_25   54 daedlpfedgsfDlvvssgalhhlsdedlekalkeiarvLkpgG 97  
                       + +++pf++g f ++v+++     s+ +++++l+e++rvL+pgG
       EEA21442.1 1224 NGTAFPFPKGFFSACVLRFPA-ASSEGRQRHILSECKRVLRPGG 1266
                       66899************8663.356778899************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1468 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       540  (0.0301188); expected 358.6 (0.02)
Passed bias filter:                      261  (0.0145574); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.89u 0.28s 00:00:01.17 Elapsed: 00:00:00.47
# Mc/sec: 9359.78
//
Query:       EEA21443.1  [L=576]
Description: structure-specific recognition protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-31  107.6   0.1      3e-30  103.9   0.0    3.0  4  SSrecog   Structure-specific recognition protein (SSRP1)
    6.8e-31  106.6   0.2      2e-29  101.8   0.0    2.9  3  POB3_N    POB3-like N-terminal PH domain
    1.9e-27   95.5   0.0    5.8e-26   90.7   0.0    2.9  3  Rtt106    Histone chaperone Rttp106-like
  ------ inclusion threshold ------
      0.032   14.6   0.0        2.5    8.5   0.0    3.3  4  PH_TFIIH  TFIIH p62 subunit, N-terminal domain
        8.8    4.5  12.8         15    3.7  12.8    1.4  1  CDC45     CDC45-like protein


Domain annotation for each model (and alignments):
>> SSrecog  Structure-specific recognition protein (SSRP1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.9   0.0   8.5e-34     3e-30       1      69 []     101     186 ..     101     186 .. 0.96
   2 ?   -2.2   0.0       1.1   4.1e+03       5      40 ..     254     290 ..     253     292 .. 0.73
   3 ?   -2.5   0.1       1.4     5e+03      40      50 ..     323     333 ..     316     342 .. 0.74
   4 ?   -1.6   0.0      0.74   2.7e+03      12      36 ..     400     422 ..     390     424 .. 0.69

  Alignments for each domain:
  == domain 1  score: 103.9 bits;  conditional E-value: 8.5e-34
     SSrecog   1 GwNwGkaefegselvfqvdnkpafeiplsevsncnlagknEvaleFhqdddaaene.................dqLvEmRfyvPgt 69 
                 GwNwGkaef+++el+f+v+n+pafeip+se+sn+nlagknEva+eF    d ++n+                 d+LvEmRfy+Pgt
  EEA21443.1 101 GWNWGKAEFTKAELAFNVQNRPAFEIPYSEISNTNLAGKNEVAVEFALPADEKANGhiegstknrgrkaaagpDELVEMRFYIPGT 186
                 9**********************************************777777777899*************************96 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.1
     SSrecog   5 Gkaefegselvfqvdnkpa.feiplsevsncnlagkn 40 
                 G ++++  e +f   +k+  + i++s + +  l  kn
  EEA21443.1 254 GRFDIDMYEASFRLRGKTYdYKIQYSSIKKFFLLPKN 290
                 7778888888999998864489999999887555555 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 1.4
     SSrecog  40 nEvaleFhqdd 50 
                 +Ev++e++  +
  EEA21443.1 323 EEVSIELNMTE 333
                 79999998654 PP

  == domain 4  score: -1.6 bits;  conditional E-value: 0.74
     SSrecog  12 selvfqvdnkpafeiplsevsncnl 36 
                 + l+f   +kpa  ++++++s +++
  EEA21443.1 400 KSLMF--VPKPATYVQIENISVVTM 422
                 54444..478999999999998887 PP

>> POB3_N  POB3-like N-terminal PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.8   0.0   5.7e-33     2e-29       2      92 ..       3      93 ..       2      94 .. 0.98
   2 ?   -1.1   0.0      0.74   2.6e+03      13      45 ..     103     134 ..      97     140 .. 0.80
   3 ?    0.8   0.0      0.19   6.6e+02      50      86 ..     431     468 ..     391     474 .. 0.82

  Alignments for each domain:
  == domain 1  score: 101.8 bits;  conditional E-value: 5.7e-33
      POB3_N  2 efeniylelsgdsGklrlsesglgwknsktgkvvqikasdissaqWvrvargyqLrillkdgkvvrfdGFkeedfdkLskllkknfniele 92
                +feniyl+ls+++Gk++l+esg+gw++s++g+++++++s+i  aqW+r+a+g++L+il ++++v+++dGF++edf++Lsk +k ++++ +e
  EEA21443.1  3 SFENIYLDLSKQPGKCKLAESGMGWRPSGGGDTFTLDSSNIGAAQWSRAAKGFELKILSRTSGVIQLDGFDQEDFERLSKAFKVWYGVAIE 93
                8**************************************************************************************9988 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.74
      POB3_N  13 dsGklrlsesglgwknsktgkvvqikasdissa 45 
                 + Gk+++++ +l++  ++   +++i+ s+is+ 
  EEA21443.1 103 NWGKAEFTKAELAFNVQNR-PAFEIPYSEISNT 134
                 6699999999999965555.6999999999875 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.19
      POB3_N  50 vargyqLrillk.dgkvvrfdGFkeedfdkLskllkkn 86 
                 ++r++ + + lk   + ++f+  ++e+++ L++++k +
  EEA21443.1 431 ASRTFDITVSLKgGLGEHQFSNINREEQQPLEEFFKAK 468
                 56888999999944589999999**********99976 PP

>> Rtt106  Histone chaperone Rttp106-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0      0.55     2e+03      48      77 ..      51      81 ..      36      85 .. 0.78
   2 ?    0.3   0.0      0.26   9.4e+02      24      43 ..     118     137 ..     101     153 .. 0.83
   3 !   90.7   0.0   1.6e-29   5.8e-26       2      89 .]     383     474 ..     382     474 .. 0.98

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.55
      Rtt106 48 tsrtfdlvvelkk.eeveFsmidqeelegid 77
                + + f+l++  ++   ++++  dqe++e++ 
  EEA21443.1 51 AAKGFELKILSRTsGVIQLDGFDQEDFERLS 81
                56778888877555899**********9986 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.26
      Rtt106  24 gfkkPllfiplediesvsfe 43 
                 + ++P++ ip+++i+  +++
  EEA21443.1 118 VQNRPAFEIPYSEISNTNLA 137
                 4579***********99887 PP

  == domain 3  score: 90.7 bits;  conditional E-value: 1.6e-29
      Rtt106   2 gVkasrkakeGlLyflekgllfgfkkPllfiplediesvsfeRv...svtsrtfdlvvelkk..eeveFsmidqeelegidefvkskgikiks 89 
                 gVk+s ka+eGlLyfl+k+l+f ++kP++++++e+i+ v+++Rv    ++srtfd++v+lk+   e++Fs+i++ee+++++ef+k k+i+ik+
  EEA21443.1 383 GVKCSIKANEGLLYFLDKSLMF-VPKPATYVQIENISVVTMSRVggaISASRTFDITVSLKGglGEHQFSNINREEQQPLEEFFKAKNIRIKN 474
                 8*********************.**********************99899**********999****************************96 PP

>> PH_TFIIH  TFIIH p62 subunit, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.0    0.0007       2.5       3      46 ..      12      53 ..      10      72 .. 0.85
   2 ?    0.9   0.0      0.16   5.8e+02      10      39 ..     108     134 ..     103     151 .. 0.79
   3 ?   -2.2   0.0       1.5   5.3e+03      28      51 ..     273     296 ..     255     315 .. 0.78
   4 ?   -0.7   0.0      0.51   1.8e+03       3      36 ..     389     417 ..     387     428 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.0007
    PH_TFIIH  3 kKkdGtLtltekrleWtpdasssapsvsiplseIknlqispags 46
                 K++G   l e+ + W+p++++   +++++ s+I + q s+a +
  EEA21443.1 12 SKQPGKCKLAESGMGWRPSGGG--DTFTLDSSNIGAAQWSRAAK 53
                699***************7764..46************999865 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.16
    PH_TFIIH  10 tltekrleWtpdasssapsvsiplseIknl 39 
                  +t+++l++  +   ++p+++ip+seI+n 
  EEA21443.1 108 EFTKAELAFNVQ---NRPAFEIPYSEISNT 134
                 566777888764...469*********985 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 1.5
    PH_TFIIH  28 svsiplseIknlqispagsaKvmL 51 
                   +i++s+Ik+ +  p++ + + L
  EEA21443.1 273 DYKIQYSSIKKFFLLPKNDEMHTL 296
                 5789999**999988887766665 PP

  == domain 4  score: -0.7 bits;  conditional E-value: 0.51
    PH_TFIIH   3 kKkdGtLtltekrleWtpdasssapsvsiplseI 36 
                 k ++G L++ +k+l + p+     p+  +++++I
  EEA21443.1 389 KANEGLLYFLDKSLMFVPK-----PATYVQIENI 417
                 5577*************93.....3344444444 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7  12.8    0.0042        15     130     192 ..     491     572 ..     415     576 .] 0.49

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.0042
       CDC45 130 eesdeede.........eeeeeddd....deeeeeeeeedeedeeedeeeskkkrksksdeeee......sddddersrkrr 192
                 ++ +++d+         e+ee+ d+    d++++  ee d+ +e++ + + +  +++++d++++      +++++er++k++
  EEA21443.1 491 DDLSSDDDvrpdrgsadEDEESVDEdfqaDSDSDVAEEYDSAHESSGSGSGSDAEMDDADDDDAvddemdEEEEEERPKKKS 572
                 2222222234443332211111111111122222222222222222222222222233333333654433333333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (576 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       702  (0.0391544); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.44
# Mc/sec: 3905.53
//
Query:       EEA21444.1  [L=1228]
Description: cellular morphogenesis protein (Rax2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.9e-71  239.3   1.7    3.5e-70  235.8   0.0    3.4  4  Rax2      Cortical protein marker for cell polarity
  ------ inclusion threshold ------
       0.19   11.8   3.0         10    6.3   0.0    4.5  4  Kelch_4   Galactose oxidase, central domain


Domain annotation for each model (and alignments):
>> Rax2  Cortical protein marker for cell polarity
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0     0.049   4.4e+02       1      59 [.     130     186 ..     130     195 .. 0.75
   2 ?   -1.8   0.0       0.2   1.8e+03       2      29 ..     659     684 ..     658     706 .. 0.79
   3 ?   -3.7   0.1      0.73   6.5e+03       5      47 ..     956     994 ..     954     996 .. 0.68
   4 !  235.8   0.0   3.9e-74   3.5e-70       2     215 .]    1000    1211 ..     999    1211 .. 0.99

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.049
        Rax2   1 latydlktqevsslsganelpgpvtsftladsdisqlwvagkss.ngssfllkydgs.kWs 59 
                 la yd + ++v ++sg    +g v+++   +++ ++++v g+   ++s+  + ++g   W+
  EEA21444.1 130 LALYDPTLNSVRNISGL---SGVVQALLCDQDS-DSVYVGGNYMvENSTNAMIWNGAtGWQ 186
                 67888888888888665...7788887765555.777799998889999999999862466 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.2
        Rax2   2 atydlktqevsslsganelpgpvtsftl 29 
                 a y ++++++s l  +  ++gpv+s+ +
  EEA21444.1 659 AAYSTSSKTWSPLGAG--VNGPVNSILT 684
                 78999********888..8999999865 PP

  == domain 3  score: -3.7 bits;  conditional E-value: 0.73
        Rax2   5 dlktqevsslsganelpgpvtsftladsdisqlwvagkssngs 47 
                 d+++ ++s      +++g+vts+  a+++  ql++ag+ + gs
  EEA21444.1 956 DTSDGQWSRPGV--DMQGSVTSLQWASDN--QLIAAGNLTVGS 994
                 555666665533..478889988888888..777788777666 PP

  == domain 4  score: 235.8 bits;  conditional E-value: 3.9e-74
        Rax2    2 atydlktqevsslsga..nelpgpvtsftladsdisqlwvagkssngssfllkydgskWssiddinlgesttirglqvlsltnshsssdlldknqvL 96  
                  atyd+++q++ s++ga  +e+pg +++f +a +d+s++w+ag+ sngs+fl++ydgsk++s+++  +g stti glqv+ l+++h+++dll+++qvL
  EEA21444.1 1000 ATYDTSSQKWASVEGAspSEIPGAISAFGPAATDMSSYWIAGQDSNGSTFLMEYDGSKFNSAGQL-FGASTTILGLQVVGLSTNHKNTDLLNDDQVL 1095
                  8***************8889*******************************************98.******************************* PP

        Rax2   97 lvtGqlnlpdfGnasaalyngtswiPYlltsssnnekgsissifleksnsfssssdlkkkkkklsrgfVVlIgLAlALgtvallgllgiilayirkk 193 
                  l+tGql++p fGnasaalyngt ++P++l+s++ +e g+i+ +f+ek+n+fs      kk+ +ls g+VVlI++++ALg+v+l++ lgiil+++++ 
  EEA21444.1 1096 LITGQLVIPHFGNASAALYNGTALTPFILSSTARGEAGTIRGMFTEKQNTFSG-----KKSPRLSAGLVVLISFCIALGCVFLIVALGIILSRVQRY 1187
                  ****************************************************6.....9************************************** PP

        Rax2  194 regyepakp..ridenemldrVpP 215 
                  r+gy++a++  ++d+ + ++rVpP
  EEA21444.1 1188 RQGYVQAPTafQTDRPTSMRRVPP 1211
                  ***********************9 PP

>> Kelch_4  Galactose oxidase, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   0.0    0.0011        10      26      46 ..     653     673 ..     633     679 .. 0.80
   2 ?   -2.0   0.2      0.43   3.8e+03       7      38 ..     872     905 ..     869     906 .. 0.69
   3 ?    1.5   0.0     0.033     3e+02      32      43 ..     953     964 ..     948     967 .. 0.91
   4 ?   -1.0   0.0      0.21   1.9e+03      34      49 .]    1002    1018 ..     994    1018 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0011
     Kelch_4  26 tllndlylldlstntWrrlgs 46 
                   +n++ ++++s++tW++lg+
  EEA21444.1 653 RGFNHVAAYSTSSKTWSPLGA 673
                 6799**************964 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.43
     Kelch_4   7 atsipdgtiylfGGrgedg...tllndlylldlst 38 
                 + +++++t++  GG+ +     ++ln   +++lst
  EEA21444.1 872 TLAVYKDTLF-AGGAVTGSagsSTLNGFVAYNLST 905
                 5567899999.999998556666666656666665 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.033
     Kelch_4  32 ylldlstntWrr 43 
                 +++d+s+++W+r
  EEA21444.1 953 CVWDTSDGQWSR 964
                 79********87 PP

  == domain 4  score: -1.0 bits;  conditional E-value: 0.21
     Kelch_4   34 ldlstntWrrl.gslPs 49  
                  +d+s+ +W  + g++Ps
  EEA21444.1 1002 YDTSSQKWASVeGASPS 1018
                  9********99988886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1228 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       501  (0.0279436); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.81u 0.30s 00:00:01.11 Elapsed: 00:00:00.49
# Mc/sec: 7490.99
//
Query:       EEA21445.1  [L=712]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.3e-11   43.2   0.0    4.7e-11   42.1   0.0    1.5  1  Fungal_trans_2  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.1   0.0   2.6e-15   4.7e-11       2     356 ..     221     702 ..     220     707 .. 0.82

  Alignments for each domain:
  == domain 1  score: 42.1 bits;  conditional E-value: 2.6e-15
  Fungal_trans_2   2 lldyyldnvapllspvpessnpfrkvllplalsnkallhallalsafhl...............qskgpkds...........lereakryksla 70 
                     ll+++ +n   ++  ++    +f +++   alsn+ l +a +a +a +l               ++     s           +e    +y+++a
      EEA21445.1 221 LLRHFAENPGYWMDLFDLD-FYFSSLVPVKALSNPLLKYAACAYAAKQLnrvrgakaimggncsKQA----SmelwpdaenvdWEWYGAKYYDKA 310
                     6677777777777777775.78888888899999999999999999999999999988777665222....0334577778999999999***** PP

  Fungal_trans_2  71 lkelqealaelsstls...................................rnekykdiLaaiLllcsieissgdvsdwrvhLeaatsliksrgg 130
                     +++l ++l+++                                        ++++++++Laa+ +l ++e  + +   w+ hL +++sl+    +
      EEA21445.1 311 IQLLMRELQHDAGSPAplstpeafgqwqaaelcddggrarkrrrrfsnsrfSSSHSDEVLAATAILSVYEFLDATGPAWNGHLSGVKSLLDIAEI 405
                     ****9999999888888999**************************************************************************9 PP

  Fungal_trans_2 131 s...............kasssslsskarfllrifayldilssttlgrgpsfpseeyekllen.............kkeesdsgldplmGcsnsli 197
                                      +++++ls++ r    +fa +d +s++  + g++  + e + l ++             ++++ +s + + m +sn li
      EEA21445.1 406 GmmpleqesspaegvlPRKRPGLSRARRATFWNFARQDYISAFINE-GQTRLNPEDLLLWTDaglqldsngfvvpSNTDAESTMKEDM-ISNALI 498
                     999*************9***************************99.55555555555555556667777887763334444444444.8***** PP

  Fungal_trans_2 198 lliseisrLarekrsarkd..........seleplsileeaseleqrllswkprssdlepdldeterassls...............kdl..... 262
                      l+s+i++     ++ + +             +++++le+ ++l ++l+ w   + d+ ++    e+a++++               +++     
      EEA21445.1 499 WLLSKIVNFIDAGDQIQLSsaggpneqgpIGVSQNTLLERWYRLHSELDAWYRGLPDTFQPCARLEPARRPHlavgidddcpfaevwYSMpmcas 593
                     *************9999999****99999999999**************8888888888888888888888889**********99966666787 PP

  Fungal_trans_2 263 telfrlaaliylyrlvlglpps...............spevqelvkkllellellp.sspvaiasLlWplFiaGceavdeddRdfvrrrleele. 340
                     t+  ++ a+i l+   ++ ++                ++e++    ++ ++  + +  s++ i+sL+ plF++G +++++ +R+ ++++l+ +e 
      EEA21445.1 594 TMQHYHMARIILLINKPHESTArrttvtnrlksyrsiESEIRLHSYEICNISMSRMdASSR-IHSLQ-PLFVTGQCLTEPRERRTILSLLRGIEa 686
                     6666666666666555444444556666777777777777776666666664444426666.9****.******8888888*************7 PP

  Fungal_trans_2 341 qsrlgnvrrarqvlee 356
                      ++ ++  r++q+l+e
      EEA21445.1 687 DTGWATEYRVKQLLKE 702
                     7777888888888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (712 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       365  (0.0203581); expected 358.6 (0.02)
Passed bias filter:                      287  (0.0160076); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.64u 0.30s 00:00:00.94 Elapsed: 00:00:00.50
# Mc/sec: 4291.90
//
Query:       EEA21446.1  [L=597]
Description: flavin-binding monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.2e-09   35.0   0.0    4.7e-07   29.4   0.0    2.7  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
    1.7e-08   33.4   0.1    3.5e-08   32.3   0.1    1.5  1  FMO-like       Flavin-binding monooxygenase-like
    2.2e-08   33.7   0.0    2.8e-05   23.5   0.0    2.4  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    3.3e-07   30.4   0.0    7.3e-07   29.3   0.0    1.6  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
    1.1e-06   28.1   0.3    5.7e-05   22.4   0.1    2.6  3  K_oxygenase    L-lysine 6-monooxygenase (NADPH-requiring)
    1.5e-05   24.7   0.0       0.07   12.7   0.1    2.6  2  DAO            FAD dependent oxidoreductase
     0.0018   17.6   0.0     0.0085   15.4   0.0    2.0  2  Thi4           Thi4 family
  ------ inclusion threshold ------
       0.01   15.9   0.2        3.2    7.7   0.0    2.9  3  NAD_binding_9  FAD-NAD(P)-binding
      0.025   13.7   0.1       0.72    8.8   0.0    2.7  3  Lycopene_cycl  Lycopene cyclase protein
      0.044   13.0   0.0         13    4.9   0.0    2.9  3  FAD_binding_3  FAD binding domain


Domain annotation for each model (and alignments):
>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.4   0.0   2.6e-10   4.7e-07       1     178 [.       8     190 ..       8     220 .. 0.74
   2 ?    2.3   0.0     0.046        82     115     147 ..     338     375 ..     305     395 .. 0.60

  Alignments for each domain:
  == domain 1  score: 29.4 bits;  conditional E-value: 2.6e-10
  Pyr_redox_3   1 iIiGaGPaGlaaaielkkagl.edylilEkg.nignsi..yrypkemtfispsftsekleipdlnaiseetspafslkeeklsrkealeYlrevaksf 94 
                  +I GaG  Gl++ai l++     +y+i+E   ++g ++    yp     + + f s ++e++          p +  +++ + ++e+l+Y+r va+++
   EEA21446.1   8 LILGAGMSGLNFAIRLQQTYPsASYTIIESTtELGGTWsvNIYPGCGCDVASHFYSYSFELK----------PDW--SQKFALQREILDYFRDVAQKH 93 
                  699*************99864379******98888755116799999999988888888774..........432..4556778999*********** PP

  Pyr_redox_3  95 el..piklfeeVes.vkkedegfev....etske...tyeAkkviiAtGefdkPnklnipGeek.lvkhyskvkefhkya..gqkvvViGgknSavD 178
                  ++  +i+++++Ve+ v +e  g  v    + +++   +++++ v+ A G  ++P+  +i+G++  +   ++  +  h++   +++vvViG + Sa  
   EEA21446.1  94 DVvnHIEYESSVERaVWNETYGVWVsdvlDKKTGtirKVRSRVVVSAVGALSIPRECEIEGADTfKGALFHSARWDHEFDwgEKEVVVIGNGCSATQ 190
                  9955688888887514445555444222223333455899***********************75555555554444444449********999975 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.046
  Pyr_redox_3 115 evetske.tyeAkkviiAtGefd....kPnklnipGee 147
                   v+t+++ +++A+ +i+A G+      +P  ++i+Ge 
   EEA21446.1 338 GVRTRSGrDIRADAIILANGFQTqkvlHPLDTDIKGEG 375
                  35666555777777777777643222245566666665 PP

>> FMO-like  Flavin-binding monooxygenase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.3   0.1     2e-11   3.5e-08       4     203 ..       7     196 ..       4     217 .. 0.77

  Alignments for each domain:
  == domain 1  score: 32.3 bits;  conditional E-value: 2e-11
    FMO-like   4 vaviGaGvsGla.sikccle.egleptcfersddiGGlwrfkenveeGrasiyksvvsnsskemscfsdfplpedy.pnflhnsklleylklfakefdl 99 
                 v ++GaG+sGl  +i+          t  e + ++GG w           +iy     +++     +s f l+ d+   f  + ++l+y++  a++ d+
  EEA21446.1   7 VLILGAGMSGLNfAIRLQQTyPSASYTIIESTTELGGTWSV---------NIYPGCGCDVASHFYSYS-FELKPDWsQKFALQREILDYFRDVAQKHDV 95 
                 67889999998634554332135567888999999999964.........588888888888888888.66666651679999**************** PP

    FMO-like 100 lkyiqfkttvcsvkkrpdfstsGqw..evvtekegkkesavfdavmvctGhhvnphlples.fpGiekfkGqyfhsrdykepevfkgkrvlviGlGnsg 195
                 + +i++++   sv++     t G w  +v  +k g + + v   v+v +       +p+e+   G + fkG +fhs  + +   + +k v+viG G s+
  EEA21446.1  96 VNHIEYES---SVERAVWNETYGVWvsDVLDKKTG-TIRKVRSRVVVSAVG--ALSIPRECeIEGADTFKGALFHSARWDHEFDWGEKEVVVIGNGCSA 188
                 ******96...566777777889995455555544.445666666665433..33678875489*********************************** PP

    FMO-like 196 gdiavels 203
                 ++    ls
  EEA21446.1 189 TQFVPILS 196
                 98776665 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   0.0   1.6e-08   2.8e-05       2     157 ..       6     191 ..       5     227 .. 0.66
   2 !    7.7   0.0     0.001       1.8     195     264 ..     320     383 ..     287     394 .. 0.67

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 1.6e-08
                  SEEEE--SHHHHHHHHHHHH..HTS-EEEEE....TTHCHHHCSHHHHCHHHHHHHHHHHHH..................................HH CS
                  xxxxxxxxxxxxxxxxxxxx..xxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxx..................................xx RF
  Pyr_redox_2   2 dvvviGgGpAGlaaaltlaq..agakvtlve....legtclnggcllskallgvaedaeias..................................ev 59 
                  dv+++G+G+ Gl++a++l+q   +a  t++e    l+gt+  + + +   +  ++++                                       ++
   EEA21446.1   6 DVLILGAGMSGLNFAIRLQQtyPSASYTIIEstteLGGTWSVN-IYPGCGCDVASHF----YsysfelkpdwsqkfalqreildyfrdvaqkhdvvNH 98 
                  8*******************85599999996555544444333.2222222222222....1223466678888888888888788877665533322 PP

                  HHCHHHHCCCCHCCTCEEEEESCEEEEETEEECTCEEEEEESEEEE---E..EE-BCTCTTC.TTBEECCSECHHHH.HHCCSS-TSEEEEES-SHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  60 vkklnqgielllgeevvkidpgkkkvklekkkegdeekiaydklvlAtGs..sprdlgipGvaenvgklvrtldsae.alklkllpkrivvvGgGyiG 154
                    ++++++e+   +e  ++     +v +  kk+g  +k+    +v A G+   pr + i+G+ +  g l   ++sa+   + ++ +k +vv+G+G  +
   EEA21446.1  99 -IEYESSVERAVWNETYGVWVS--DVLD--KKTGTIRKVRSRVVVSAVGAlsIPRECEIEGADTFKGAL---FHSARwDHEFDWGEKEVVVIGNGCSA 188
                  .123333333333333333222..2333..34488999999********75588899*****6666666...3333315566888899*******999 PP

                  HHH CS
                  xxx RF
  Pyr_redox_2 155 vEl 157
                  + +
   EEA21446.1 189 TQF 191
                  876 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.001
                  HTTEEEEESCEEEEEEETTEEEEEEETTSCEEEESEEEE-S-EEES-HHCSHCCT-EEEETTEEE--TTS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 195 keGvevklgtsvkeidgngeklevvledgeeidadlvvvavGvrpstelleeklglelderggivvdefl 264
                  +e+ e+++   v+++++ g    v + +g+ i ad +++a G++ ++ l    l   ++  gg+  de+ 
   EEA21446.1 320 NENMELVWDDPVVAVTETG----VRTRSGRDIRADAIILANGFQTQKVL--HPLDTDIKGEGGVSLDEHW 383
                  4455555555555555444....56666666777777777777766655..4555555556666666554 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.3   0.0   4.1e-10   7.3e-07       1      52 [.       9      62 ..       9      77 .. 0.92

  Alignments for each domain:
  == domain 1  score: 29.3 bits;  conditional E-value: 4.1e-10
                   EE--SHHHHHHHHHHHCC..TEEEEEE-SSSSSSGGG-EECETTCEECTS---E CS
  NAD_binding_8  1 IvGaGlsGlvaAylLaka..gfdvlllekrdrlGGraasyevpgvrvdygahif 52
                   I+GaG+sGl +A +L++    ++ +++e+ + lGG ++ + +pg+ +d+  h +
     EEA21446.1  9 ILGAGMSGLNFAIRLQQTypSASYTIIESTTELGGTWSVNIYPGCGCDVASHFY 62
                   89***************77899***************************99987 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0     0.035        63       4      35 ..       6      37 ..       4      47 .. 0.66
   2 !   22.4   0.1   3.2e-08   5.7e-05      91     208 ..      75     193 ..      69     222 .. 0.80
   3 ?   -2.0   0.0      0.82   1.5e+03     322     341 ..     340     359 ..     307     360 .. 0.77

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.035
  K_oxygenase  4 DligiGiGpsnLsLailleevkkelkalfler 35
                 D+ + G+G s L +ai+l+++    +   +e 
   EEA21446.1  6 DVLILGAGMSGLNFAIRLQQTYPSASYTIIES 37
                 67777777777777777777765555555554 PP

  == domain 2  score: 22.4 bits;  conditional E-value: 3.2e-08
  K_oxygenase  91 flpsRkefedYlrWvasqle..eqvrfgeeveevepdeeeeeelltveskdaegeeeelearnlvlgvGtepkiPevlekle...gkervvHsseyle 183
                  ++ + +e  dY r va++ +  ++++++++ve+  ++e  +  + +v  ++++g+ +++++r +v +vG   +iP  +e       k  ++Hs++  +
   EEA21446.1  75 KFALQREILDYFRDVAQKHDvvNHIEYESSVERAVWNETYGVWVSDVL-DKKTGTIRKVRSRVVVSAVGA-LSIPRECEIEGadtFKGALFHSARWDH 170
                  5667788899******99776689*************98654444444.348999999999998888886.5799998743333446899*******9 PP

  K_oxygenase 184 rkeellakkriaVvGsGqSaaeife 208
                  +   +  +k+++V+G G Sa + + 
   EEA21446.1 171 EF--DWGEKEVVVIGNGCSATQFVP 193
                  99..79999***********98665 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 0.82
  K_oxygenase 322 esgeeetlevdavvlATGYr 341
                   + + + +++da++lA G++
   EEA21446.1 340 RTRSGRDIRADAIILANGFQ 359
                  4556678999********97 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   0.1   3.9e-05      0.07       1      40 [.       6      48 ..       6     168 .. 0.73
   2 !    9.4   0.0    0.0004      0.73     159     226 ..     321     380 ..     232     425 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 3.9e-05
                EEEEECTSHHHHHHHHHHHHT.T...EEEEESSSSTTSSGGGSS CS
         DAO  1 dvviiGGGiiGlstAyeLarr.g...VtllekgdiagsgaSgrn 40
                dv+i G+G+ Gl  A  L++  +    t++e+  ++g g+ + n
  EEA21446.1  6 DVLILGAGMSGLNFAIRLQQTyPsasYTIIESTTELG-GTWSVN 48
                8*****************76665799*********99.887766 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.0004
                 TT-EEEESECEEEEEEEETCEEEEEEECT.EEEEEEEEEEE--GGGHH.HHHTTCTTTSEEEEEEEEEEE CS
         DAO 159 lGveilegtevtgleeedgkvwgverttp.gendaadavVnaaGawsd.llgllkeldlpispvrgqvlv 226
                    e++   +v+++       +gv   t+ g+  +ada+++a+G +++  l   ++ld  i++  g +l 
  EEA21446.1 321 ENMELVWDDPVVAVT-----ETGV--RTRsGRDIRADAIILANGFQTQkVL---HPLDTDIKGEGGVSLD 380
                 456666677888873.....4788..556588745599*********9777...8887777776666654 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   4.7e-06    0.0085      17      58 ..       4      45 ..       2      48 .. 0.91
   2 ?   -1.3   0.0       0.6   1.1e+03      14      35 ..     173     194 ..     165     205 .. 0.73

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 4.7e-06
                EEEEEEE--SHHHHHHHHHHHHC.TTS-EEEEESSSS--TTTT CS
        Thi4 17 esDvvivGaGssGLtaayylakk.pdlkvailersvspGGGaw 58
                ++Dv+i GaG sGL  a  l +  p    +i+e+   +GG +w
  EEA21446.1  4 DTDVLILGAGMSGLNFAIRLQQTyPSASYTIIESTTELGG-TW 45
                68********************99**********999876.45 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.6
                 HHTEEEEEEE--SHHHHHHHHH CS
        Thi4  14 kyaesDvvivGaGssGLtaayy 35 
                 ++ e +vv++G G s      +
  EEA21446.1 173 DWGEKEVVVIGNGCSATQFVPI 194
                 67899********997655555 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.0    0.0018       3.2       2      96 ..       9     110 ..       8     147 .. 0.63
   2 ?   -2.9   0.0       3.4   6.1e+03      53      72 ..     208     238 ..     202     241 .. 0.77
   3 ?    5.0   0.0     0.012        22     134     155 ..     337     358 ..     318     359 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0018
  NAD_binding_9   2 ivGaGprGlavlerLlarakkkspleitlfdpsepgagrvwrtdqseelllNvpasemslftddp..........ptfaeWlrergalee.aeeld 86 
                    i GaG++Gl ++ rL +      + + t+++ ++   g+ w+ +  +     v+++  s+  + +          ++  ++ r+ +++++ +++++
     EEA21446.1   9 ILGAGMSGLNFAIRLQQTY---PSASYTIIESTTEL-GGTWSVNIYPGCGCDVASHFYSYSFELKpdwsqkfalqREILDYFRDVAQKHDvVNHIE 100
                    89**************995...88999999998887.78998877777666666666665444443444555555444444444433222466666 PP

  NAD_binding_9  87 pddfvpRaly 96 
                     ++ v Ra++
     EEA21446.1 101 YESSVERAVW 110
                    6666666664 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 3.4
  NAD_binding_9  53 Nvpasemslftddp...........ptfaeW 72 
                     +pa++++ f+ +p            +f +W
     EEA21446.1 208 RTPAKKVTQFARQPhwlaerpnpvySSFFKW 238
                    5889999999998877777777777777777 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.012
  NAD_binding_9 134 qavlladgaslaadaVvLAlGh 155
                      v++++g+ ++ada++LA G 
     EEA21446.1 337 TGVRTRSGRDIRADAIILANGF 358
                    35889**************995 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   0.0    0.0004      0.72       1      36 [.       6      41 ..       6      50 .. 0.89
   2 ?    0.9   0.0       0.1   1.8e+02     128     167 ..     130     170 ..      88     180 .. 0.74
   3 ?   -0.8   0.0      0.34   6.1e+02     117     146 ..     334     362 ..     320     376 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0004
  Lycopene_cycl  1 DvvviGaGpAglslAarlteakpglkvvlieaspsl 36
                   Dv++ GaG  gl  A rl +  p  + ++ie+  +l
     EEA21446.1  6 DVLILGAGMSGLNFAIRLQQTYPSASYTIIESTTEL 41
                   9*****************999999999999987766 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.1
  Lycopene_cycl 128 rkirarlvvdarglaslkkarr.lglQtfyGvevevdnppf 167
                    rk+r+r+vv a g+ s +++ +  g  tf G + ++++  +
     EEA21446.1 130 RKVRSRVVVSAVGALSIPRECEiEGADTFKGALFHSARWDH 170
                    59***********9998865551589999999988876444 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 0.34
  Lycopene_cycl 117 ageslvvleggrkirarlvvdarglaslkk 146
                    ++e+ v +  gr ira +++ a g ++ +k
     EEA21446.1 334 VTETGVRTRSGRDIRADAIILANG-FQTQK 362
                    467788999***************.66654 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.0    0.0073        13       1      22 [.       4      25 ..       4      39 .. 0.89
   2 ?    4.1   0.0     0.013        23     140     171 ..     119     150 ..      66     218 .. 0.75
   3 ?   -0.1   0.0      0.24   4.2e+02     134     191 ..     328     387 ..     257     426 .. 0.69

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.0073
                   EEEEEEE--SHHHHHHHHHHHH CS
  FAD_binding_3  1 etdVlIVGaGpaGlmlallLse 22
                   +tdVlI GaG +Gl  a  L++
     EEA21446.1  4 DTDVLILGAGMSGLNFAIRLQQ 25
                   69************99988875 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.013
                    CEEEECCTTEEEEEEEEEEEE--GTT-HHHHH CS
  FAD_binding_3 140 aevrdketgeeetvrakYlvGaDGgrStvrkt 171
                    ++v+dk+tg++++vr++ +v a G+ S+ r++
     EEA21446.1 119 SDVLDKKTGTIRKVRSRVVVSAVGALSIPREC 150
                    5688***********************98875 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.24
                    CCCCCCCEEEECCTTEEEEEEEEEEEE--GTT-H.HHHHHTGGEEEEEEEE.EEEEEEEE CS
  FAD_binding_3 134 deegvtaevrdketgeeetvrakYlvGaDGgrSt.vrktlgiefegeetvy.eagvldvl 191
                    d+  v+ + ++ +t   +++ra+ ++ a G++++ v + l+++++ge++v  + ++ +v 
     EEA21446.1 328 DDPVVAVTETGVRTRSGRDIRADAIILANGFQTQkVLHPLDTDIKGEGGVSlDEHWQQVS 387
                    444555555566666778999999999999998538899999999998873134444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (597 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       465  (0.0259356); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.63u 0.31s 00:00:00.94 Elapsed: 00:00:00.47
# Mc/sec: 3822.27
//
Query:       EEA21447.1  [L=1139]
Description: UV-damaged DNA binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.2e-131  439.7   0.1   3.2e-131  438.3   0.0    1.7  2  MMS1_N    Mono-functional DNA-alkylating methyl methanesulfon
    3.4e-70  236.9   0.0    5.6e-67  226.3   0.0    3.2  3  CPSF_A    CPSF A subunit region
  ------ inclusion threshold ------
       0.03   13.9   0.0       0.13   11.8   0.0    2.0  1  PQQ_2     PQQ-like domain


Domain annotation for each model (and alignments):
>> MMS1_N  Mono-functional DNA-alkylating methyl methanesulfonate N-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  438.3   0.0  5.3e-135  3.2e-131       1     488 [.      74     574 ..      74     575 .. 0.92
   2 ?   -2.4   0.2      0.23   1.4e+03     416     467 ..     922     990 ..     877    1009 .. 0.44

  Alignments for each domain:
  == domain 1  score: 438.3 bits;  conditional E-value: 5.3e-135
      MMS1_N   1 DlLvvgsdsgelvflsynpeknqfetvhshetlgksgsrrsqpGqylavDPkgraiavsayekvflvyslkk.keilnr.................eal 81 
                 D+L+vg+d++ +++l++++ek +++t++s+++l+++ sr  q G+++++DP+g++++++++e++++v ++ + ++++ +                 + +
  EEA21447.1  74 DHLFVGTDQNTYFTLKWDSEKRRVRTERSYVDLADKASRACQNGDRCLIDPSGKYMTLEIFEGIITVLPIIQlHKKRGKppvlktshysnpdeptpQIG 172
                 9***********************************************************************843333367776677777788787777 PP

      MMS1_N  82 llssplearksegvilsmvFldpgykeednpiialleqdrrgkteltlyewdlglnlvrkisktsepkk...nldsganlLiplpkp.ggvlVcgetii 176
                 +l +p+  r+ e+ ++s++Fl++++k+  +p +all++d+++k++l+++e+++   +  + ++t    +   +ld ga++Lip+p p gg+lV get i
  EEA21447.1 173 ELGEPMMTRIDELMVRSSAFLHVESKA--HPRLALLHEDNQRKVKLKIRELSFEASAEPVFQETE---DfteELDLGASHLIPVPAPlGGLLVLGETCI 266
                 77788888*****************98..8***********************877555544444...34458*************9677********* PP

      MMS1_N 177 tykdildqedirkkswarPrrekatnfvawekldsfffllatedGdLylleiekdedsgkvvtsislkyfdtvsvasalvilksgfLfvasefGdgqly 275
                  y d+      ++++++ P++e at+fvaw ++d++++lla+++G+L++l++  + ds+++v++++l+y+++ s+as l++l+ g+ f++s++Gd+q++
  EEA21447.1 267 KYIDDA-----KNETISNPLDE-ATIFVAWVQVDGQRWLLADDYGRLFFLML--VLDSQNEVEGWKLDYLGEASRASVLIYLGAGMTFIGSHQGDSQVI 357
                 ****93.....4445567***9.*****************************..667779*************************************** PP

      MMS1_N 276 qieargeddknleliqtldNlaPilDfkvv....kes....dlasegqdqiytcsGagkrgsLrelRsGieveelavseepgspitgvWtlklssedey 366
                 +i++      ++e+iqt++N+aPilDf+++    +e+    +++s+gq++i+t+sGa+++g+Lr++RsG+++ el+v++e+ ++it++W+l+ ss  ++
  EEA21447.1 358 RISEG-----SFEIIQTISNIAPILDFTIMdlgaREGenytHEFSSGQARIVTGSGAFNDGTLRSVRSGVGMDELGVLGEM-EHITDMWALQISSPGDF 450
                 ****7.....5*******************998733368899***************************************.568**********9*** PP

      MMS1_N 367 ddylvlSfvneTlvlsidgdgeveevtedsglllsvpTLaagnlgdgslvQVtpngirliradk..rvsewkppngksiiaaaangeqllvalsgrelv 463
                 +d+lv++fvneT+v+++++dgevee++e+ gl+l ++TL+ +nl++g+++ Vt++g+ + ++d+  ++s+w+p++ ++i+++a+n+e l+v++ g+ + 
  EEA21447.1 451 SDTLVVTFVNETRVFRFSSDGEVEELDEFLGLNLAENTLLSSNLPGGRIIHVTESGVSIADTDSgmVTSKWSPDG-HTITSVACNDERLVVVTGGQIIA 548
                 **************************9999***********************************8888*****6.6********************** PP

      MMS1_N 464 yfel.dlieevekkdleslsevscls 488
                 ++++  ++++ ++kd++++++vs ++
  EEA21447.1 549 TLDItGDLKVLSQKDFGKDNQVSGVT 574
                 ****66***********9****9886 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.23
      MMS1_N 416 vQVtpngirliradk...rvsewkppng........k......siiaaaangeqllvalsgrelvyfel 467
                 + Vt+++i++ +  k   +v + k++          +      +  +a + ++q lv+ ++++l++++ 
  EEA21447.1 922 IAVTDKTIVVADLMKsisIVESNKTDALtmeakevaRhfatvwTTAVADIGSNQWLVSDAEGNLIVLRR 990
                 334444444444333333333333333223332222023333244444455666666666666666643 PP

>> CPSF_A  CPSF A subunit region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.0      0.02   1.2e+02     184     220 ..     293     327 ..     277     353 .. 0.86
   2 !    4.5   0.0     0.003        18     168     218 ..     611     660 ..     598     711 .. 0.85
   3 !  226.3   0.0   9.4e-71   5.6e-67       2     322 .]     783    1107 ..     782    1107 .. 0.92

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.02
                 --SSSEEEEEETTSEEEEEE--TTSGGGTTTT.EEEE CS
      CPSF_A 184 vdgedtvlvaDkfgnlfvlrydpeasessdgdprlee 220
                 vdg + +l+aD+ g lf l +  + +++++g  +l+ 
  EEA21447.1 293 VDG-QRWLLADDYGRLFFLMLVLDSQNEVEGW-KLDY 327
                 478.89****************9999999987.7765 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.003
                 EEEESS---EEEEEEE--SSSEEEEEETTSEEEEEE--TTSGGGTTTT.EE CS
      CPSF_A 168 fardtqkrwvtaaeflvdgedtvlvaDkfgnlfvlrydpeasessdgdprl 218
                 +a    +r v  ae+l d ++t+ v+ ++g+++++ yd  +s s+ g+++l
  EEA21447.1 611 VASEAFPRTVLLAEILADSSSTLFVSMADGSVVTFSYD-AESHSLTGTNKL 660
                 567778999*******99977*****************.678888888765 PP

  == domain 3  score: 226.3 bits;  conditional E-value: 9.4e-71
                  -EEEEE-T..TT-EEEEE--TTEEEEEEEE--B-SSTTT...---B--EEEEEEE---SSS--E.EEEEEEEEEE-SS--EEEEEEEEEEEES---- CS
      CPSF_A    2 ssiklvdpiskeeidsleLeenEavlsvksvelessett...kekkellvVGtafnlgedpaarsGrilvfeiievpetnrkLklvhkeevkgavta 95  
                  s++ l d+i ++++ds++L+++E+v+sv+++++ +++++      k++++VGta++ +e  ++  Gril+fe+++    nrkL l+ +++vkga++a
  EEA21447.1  783 SQFVLADEIMFRKLDSFDLKPDELVESVIRAQMVVGKDRydePIYKDRFIVGTAYLDDETAESIRGRILLFEVDS----NRKLSLFLEHPVKGACRA 875 
                  8899*******************************999855533477**********99997777**********....79**************** PP

                  EEEETTEEEEE-SSEEEEEEE-TTS.....-EEEEEEEE-SS-EEEEEEETTEEEEEESSS-EEEEEE-S...SS--EEEEEEESS---EEEEEEE- CS
      CPSF_A   96 laefqGrllvgvgqkvrvydlgedk.....tLlrkafldtqlyvvslkvlgnriivgDlmkSvtfveyde...enyklilfardtqkrwvtaaeflv 184 
                  la + +++++++ ++v++++++ +      +L + a ++t++++v++ v+ + i+v+DlmkS+++ve ++     ++ +++ar++ ++w+ta++ + 
  EEA21447.1  876 LAMMGDYIVAALVKTVVIFEVTGQPqtgkySLQKAAVYRTSTAPVDIAVTDKTIVVADLMKSISIVESNKtdaLTMEAKEVARHFATVWTTAVADI- 971 
                  *********************9988888999***********************************99997655555679*************999. PP

                  -SSSEEEEEETTSEEEEEE--TTSGGGTTTT.EEEEEEEEE-SS----E...EEEE.SSS--S-EEEEEE-TTS-EEEEEE.--HHHHHHHHHHHHH CS
      CPSF_A  185 dgedtvlvaDkfgnlfvlrydpeasessdgdprleeraefhlgeivtslrkgslvpgeaesssspqllyatldGsigllvPliseeeyrrlqaLqqq 281 
                   g++ +lv+D++gnl+vlr++ +  +++d + rle+++e  lge+v+++r++++ ++ +   ++p+++++t++Gsi+ l++li+ e++++l++Lq+ 
  EEA21447.1  972 -GSNQWLVSDAEGNLIVLRRNVDGMTEEDRR-RLEVTSELLLGEMVNRIRPVNIPQT-STMAVTPKAFLGTVEGSIY-LFALINPEHQDFLMRLQTA 1064
                  .5479****************8777777777.*********************5545.55558**************.9999*************** PP

                  HHHHS--SSS--HHHHS---....----.---EEHHHHHHHHH CS
      CPSF_A  282 LrkelkhlgGldhrafRsyysp..kseevkgviDgdllerfld 322 
                  +++ ++++g + +++fR+++s+  ++ee+ +++Dg+l+erfld
  EEA21447.1 1065 ISAYVDSPGLMPFNKFRAFRSTvrEAEEPFRFVDGELIERFLD 1107
                  ********************99766666*************96 PP

>> PQQ_2  PQQ-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   2.2e-05      0.13      31     137 ..     492     595 ..     460     662 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 2.2e-05
       PQQ_2  31 ravlsggtlfvatgggrlvaldaatGkvlWettlegpvvgaplvaegrvvvvasdgqlialdaedGkrlWstqqrseepaelrssaspavagdtvvvge 129
                   + +gg+++ + ++  ++ +d+ +G v+ + +++g + ++   +++r+vvv++++ +++ld+ +G+++   q++ +++  +++++ p   +++ ++++
  EEA21447.1 492 SNL-PGGRIIHV-TESGVSIADTDSGMVTSKWSPDGHTITSVACNDERLVVVTGGQIIATLDI-TGDLKVLSQKDFGKDNQVSGVTIPPAPSQVCIAAF 587
                 455.77788877.66677779*****************************************4.44443333677777777788888887888888888 PP

       PQQ_2 130 ssgklval 137
                 + + lva+
  EEA21447.1 588 PQNALVAV 595
                 87777664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1139 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       374  (0.0208601); expected 358.6 (0.02)
Passed bias filter:                      356  (0.0198561); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.76u 0.30s 00:00:01.06 Elapsed: 00:00:00.44
# Mc/sec: 7765.33
//
Query:       EEA21448.1  [L=342]
Description: 3-hydroxyisobutyrate dehydrogenase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.4e-31  109.8   0.0      2e-31  109.3   0.0    1.2  1  NAD_binding_2   NAD binding domain of 6-phosphogluconate dehy
    2.1e-30  105.5   0.0    3.7e-30  104.7   0.0    1.4  1  NAD_binding_11  NAD-binding of NADP-dependent 3-hydroxyisobut
     0.0044   17.6   0.0     0.0089   16.6   0.0    1.5  1  F420_oxidored   NADP oxidoreductase coenzyme F420-dependent
  ------ inclusion threshold ------
       0.14   11.5   0.0       0.22   10.9   0.0    1.4  1  2-Hacid_dh_C    D-isomer specific 2-hydroxyacid dehydrogenase


Domain annotation for each model (and alignments):
>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  109.3   0.0   4.5e-35     2e-31       2     155 ..      33     205 ..      32     207 .. 0.90

  Alignments for each domain:
  == domain 1  score: 109.3 bits;  conditional E-value: 4.5e-35
                    EEEE--SHHHHHHHHHH...HHTT-EEEEE-SSHHHHHHHHHTT.......EEE-SSHHHHHHHCSEEEE-SSSHHHHHHHHHS.....HCCC--T CS
  NAD_binding_2   2 igfiGlGvMGsnmalnl...lkagykvavynrtkekveelvaeg.......akaaesieelvasldvvitmvkagkavdevieg.....llealkk 82 
                     gfiGlG MG +ma+ l   +    +++v+++++++++++vae        ++ ++s++ l+++   vit +++  +v++v  +      l++l++
     EEA21448.1  33 WGFIGLGRMGYPMAKTLrarIPPSDTLIVHDVNEQAMRQFVAEAktastgpVEFTDSARTLAEKSTNVITSLPQPVHVRQVFHSilkpgPLPQLEQ 128
                    59***************65556799******************9889999999999999999999*******************6555556899** PP

                    T-EEEE-S---HHHHHHHHHHHHHTT.-EEEEEEEESHHHHHHHT-EEEEEEE-HH...HHHHHHHHHHHHEEEEEE CS
  NAD_binding_2  83 gdilidgstsspedtrelakelkekg.lkfldaPVSGGeegAekGtLsimvGGsee...afervkpvleaigakvth 155
                    ++++id+st++p +++e+a ++++ +  +f+daP SGG+  Ae+GtLs+m G+s++    ++rvk+vl+ +g++  h
     EEA21448.1 129 ERLFIDCSTIDPVTSKEIAYAVQAPNqGRFVDAPMSGGVVAAEAGTLSFMFGASSKtgaLVDRVKSVLSLMGKNAWH 205
                    *********************9886549************************9887343699***********9874 PP

>> NAD_binding_11  NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.7   0.0   8.4e-34   3.7e-30       1     122 []     210     336 ..     210     336 .. 0.93

  Alignments for each domain:
  == domain 1  score: 104.7 bits;  conditional E-value: 8.4e-34
  NAD_binding_11   1 GaGqavKlvnnlllainlaaasEalvlaekaGldpekvlevinassgrsnalenk......lpqrvlsrdfdpgFaldlmlKDlglalelareag 89 
                     G+G   Kl+nn++lain +a++Ea+ l+ + Gldp+++ ++in+s+gr++ +e +      ++++++srd++ gF+++lm+KDl+la+++a+e g
      EEA21448.1 210 GTGVSGKLANNYILAINNIAVAEAMNLGIRWGLDPKVLADMINSSTGRCWPSEVNnpvpgvVEKSPASRDYEGGFSIGLMRKDLKLAIDAAQESG 304
                     789999********************************************9755555566699******************************** PP

  NAD_binding_11  90 aplpllalaeqlyaaaaaegggdaDhsaivrll 122
                     apl+l+  a++ly+a+ ++ ++++D+s ++++l
      EEA21448.1 305 APLELADKARRLYEAV-EDIHPGKDFSVVYKYL 336
                     **************98.7889999***999975 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0     2e-06    0.0089       3      94 ..      34     135 ..      32     137 .. 0.87

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 2e-06
                    EEETTSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC......-EEECECHHHHHHH-SEEEE-S-.HHHHHHHHHHC.....GHHHH CS
  F420_oxidored   3 giiGaGnmgealasgllaagaqpheivvansrnpekaeelaeelg......vkvtavdneeaaeeadvvvlavk.pedveevlsel.....akdal 86 
                    g+iG G+mg  +a+ l a+  +p++ +++ + n++ ++++ +e++      v+ t  ++ ++ae+++ v+ +++ p +v +v  ++      +++ 
     EEA21448.1  34 GFIGLGRMGYPMAKTLRAR-IPPSDTLIVHDVNEQAMRQFVAEAKtastgpVEFTD-SARTLAEKSTNVITSLPqPVHVRQVFHSIlkpgpLPQLE 127
                    9*************88888.6999988899**********9999999999888888.999999999999999975788999999998888888888 PP

                    TTSEEEEE CS
  F420_oxidored  87 kgklvisv 94 
                    +++l+i++
     EEA21448.1 128 QERLFIDC 135
                    88888887 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   4.9e-05      0.22      26      57 ..      20      51 ..       4     150 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 4.9e-05
                  TCCGSBS-GTTSEEEEES-SHHHHHHHHHHHH CS
  2-Hacid_dh_C 26 ekallgkelsgktvGiiGlGrIGqavakrlka 57
                  ++ ++ +  ++ t+G iGlGr+G  +ak+l+a
    EEA21448.1 20 QRLFSTSLRRNTTWGFIGLGRMGYPMAKTLRA 51
                  3334444557899***************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       276  (0.0153941); expected 358.6 (0.02)
Passed bias filter:                      265  (0.0147805); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.43u 0.23s 00:00:00.66 Elapsed: 00:00:00.39
# Mc/sec: 2661.85
//
Query:       EEA21449.1  [L=2620]
Description: cell morphogenesis protein (PAG1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   3.4e-214  712.9   0.0   7.5e-214  711.7   0.0    1.6  2  MOR2-PAG1_N    Cell morphogenesis N-terminal
      1e-92  310.6   0.1      1e-92  310.6   0.1    2.7  3  MOR2-PAG1_C    Cell morphogenesis C-terminal
    2.9e-30  104.7  16.3    1.8e-12   45.8   0.5    3.8  3  MOR2-PAG1_mid  Cell morphogenesis central region
  ------ inclusion threshold ------
       0.36   11.5   2.1        1.2    9.8   2.1    1.9  1  Inhibitor_I9   Peptidase inhibitor I9


Domain annotation for each model (and alignments):
>> MOR2-PAG1_N  Cell morphogenesis N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  711.7   0.0  1.7e-217  7.5e-214       1     551 []     381     960 ..     381     960 .. 0.98
   2 ?   -3.9   0.2       1.1   4.9e+03     463     507 ..    1830    1877 ..    1807    1881 .. 0.53

  Alignments for each domain:
  == domain 1  score: 711.7 bits;  conditional E-value: 1.7e-217
  MOR2-PAG1_N   1 eRkslvsiyilcrvLieilkqstkeslteelgekLeeivFkqlkkadpeslsssplrlanwnlfAelLGvlSeirFasVsdrFiaeLeklrke..... 93 
                  eR+++vs+y++crvLiei++qst e+++ e+ e+Le+ivF+qlk +dpe++++splr+anw+++++lLG +Sei+F+sV+ rFi+eLe+++ke     
   EEA21449.1 381 ERRATVSVYLVCRVLIEIFNQSTVEAIGTEMTERLEDIVFGQLKAVDPEQIAASPLRMANWRIYGQLLGKMSEINFTSVTMRFINELERYQKEaalrg 478
                  8********************************************************************************************99998 PP

  MOR2-PAG1_N  94 askeleaklellirGmrylklkvypeeafeesadFlkslakffeeakgsevkhAyaellselLlpvaasataevnhpkwaeavellypraakmskkpk 191
                  +++e +ak+elli Gmr++ +k+ypeea+++s+++++s+a++f +a+g++vk+Ay+ +++++L ++aa+  ++v hp w++++e + pr+++m  kp+
   EEA21449.1 479 QTSEFDAKAELLILGMRHFSIKTYPEEAWTKSCEYMRSIARLFVNAHGQRVKQAYCYIIEKVLISIAANPACDVGHPIWKDFLEIITPRLSQMIAKPR 576
                  77889********************************************************************************************* PP

  MOR2-PAG1_N 192 hwnaafpLvttlLCvspkefFlanWlsllesllsklKdkstravalealsrllwvYlyRckeslntttkkLeeilkllfpkgkrklitpddelleplv 289
                  hw +afpL t+lLCvs+k+ F+++Wls+  +l ++l+d++tr +al+al+rllw+Yl+R+++++n t k+ +e++k+++p+g+r+++t+++++++pl+
   EEA21449.1 577 HWMTAFPLQTILLCVSSKDAFASQWLSIALNLPARLRDRPTRGLALQALCRLLWTYLFRYPDPPNITLKRVDEVIKVALPPGRRTYLTTEPSVADPLI 674
                  ************************************************************************************************** PP

  MOR2-PAG1_N 290 qiirfiaskhldfafkniifpllnaelfsss...klenlepermiigirAflailsdlekkeq.rPpfPtss.........................d 358
                  q+ir+i++k +d++f+niifpl+n++lf s+   k+e++epe+m++gir+fl i+ dle+++q  PpfP                            +
   EEA21449.1 675 QLIRMIGFKLPDLCFRNIIFPLINSDLFLSGrelKIEQMEPEKMVVGIRSFLSIMCDLENGDQlYPPFPAGPisthfvdipnfllpprpqlladpkpR 772
                  ***************************87778888***********************************77899*********************98 PP

  MOR2-PAG1_N 359 asekeedllsrpvgtsalsetkkeylakaglkkyyeevskilgkililldqtvGrqlvldekls.s.pkt.iaesfsf.rkddha.avdekqakleLl 451
                  a+ ++++ ls pv+ s+l+e++k+y         y ++++ilgki+il+d+t+G+q++ldek+s s pkt i+e+fsf r+ddha  ++++q++++Ll
   EEA21449.1 773 AVVSDPSALSCPVNVSKLNEVAKAY---------YVQFCEILGKITILCDNTFGGQAALDEKFSgStPKTpISEAFSFgRRDDHAsLIEQRQSFYDLL 861
                  889999*********9999998888.........*****************************9647***********88899885777********* PP

  MOR2-PAG1_N 452 ktaiealPrclpesipfkslielLcrgtvHvdpeiaesaaqaLkaliarqkkrqqvvtgfarfifkfddkyssvsevsmlgseeieslLklyvelLei 549
                  ++a++alPrcl+++ipf+sli+lLc+gt+Hv+p+ia+s+a++Lk+ iarq ++qqv++gfarfif+fd++ys++s+ +mlg+++ies+L+lyvelL+i
   EEA21449.1 862 HVAVQALPRCLSDHIPFNSLINLLCTGTAHVQPNIARSSAESLKS-IARQMHAQQVTIGFARFIFNFDARYSTMSDEGMLGPGHIESTLTLYVELLRI 958
                  *********************************************.**************************************************** PP

  MOR2-PAG1_N 550 Wi 551
                  Wi
   EEA21449.1 959 WI 960
                  *7 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 1.1
  MOR2-PAG1_N  463 pesipfkslielLcrgtvH..vdpeiaesaaqaLkaliar.qkkrqqv 507 
                   + + + ++++  L++ +v+  +++e++++a qa+++++++ +k   +v
   EEA21449.1 1830 TVQEQAREMLVHLIHELVSskLQDEVSTEARQAIEHFVDSiRKSDASV 1877
                   444333343333333333312577888888888888877765555555 PP

>> MOR2-PAG1_C  Cell morphogenesis C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   1.1       2.8   1.2e+04     181     240 ..    1795    1854 ..    1790    1857 .. 0.69
   2 ?   -0.1   0.0      0.15   6.7e+02     163     206 ..    1943    1986 ..    1940    1997 .. 0.91
   3 !  310.6   0.1   2.3e-96     1e-92       1     253 []    2002    2252 ..    2002    2252 .. 0.99

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 2.8
  MOR2-PAG1_C  181 lvlllgllengpewlrrktlqiLkvllqeidlrkpaeisslgsdl.lspllrlletelcse 240 
                   +++l+ l+    +   + ++++L+v+l   d+  + ++++   ++ ++ +  l++++l  e
   EEA21449.1 1795 MIFLVDLIVGPVTLAVQDVIKLLHVVLILWDHY-TFTVQEQAREMlVHLIHELVSSKLQDE 1854
                   667777777777777788899999999998888.556665555541666677888877665 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.15
  MOR2-PAG1_C  163 qvvkalreayfpehesealvlllgllengpewlrrktlqiLkvl 206 
                   q+++++ ++  p++ +++l  l + +  +++ ++  +++iL  l
   EEA21449.1 1943 QLFRCISKSLEPKMLADMLARLSNTIADEETDYQTFSMEILTTL 1986
                   78899999999*****************************9765 PP

  == domain 3  score: 310.6 bits;  conditional E-value: 2.3e-96
  MOR2-PAG1_C    1 pqlFWttvAcLetdfeseFlealelLeklldkldlddpevvevllksqpqkwegdfeglqalvlkGlrssetleatlellskLtklsddelvdssd 96  
                   pqlFWtt+AcL+t++e eF+e++++Leklldk+d++dp+vv++l   qp++weg+f g+q lv+kGl+sse++++tl+ll++Lt+l+d+ lv+ + 
   EEA21449.1 2002 PQLFWTTCACLNTIHEVEFMESIRMLEKLLDKIDMGDPNVVATLSGAQPPRWEGAFTGIQDLVYKGLKSSESFNETLSLLHRLTPLPDNILVG-ES 2096
                   9********************************************************************************************.66 PP

  MOR2-PAG1_C   97 srllllilalLPrllqaleekeedqkvlevAenlaalaeekglenLarvltsyakgrfrtkddflkqvvkalreayfpehesealvlllgllengp 192 
                   +rll++ila++P++l++++++++d +++e A+ l ++a++ g+e+La++l  +a+++ ++++dfl+++v+ ++++yfp +e+++lv+++g+l+n +
   EEA21449.1 2097 NRLLFAILANIPHFLHQFDADSNDAEIMERANLLGQVADRRGFERLAACLVGFANAQWKKEQDFLQHIVSEICSYYFPAQEVQTLVFVMGCLTNAT 2192
                   6*********************************************************************************************** PP

  MOR2-PAG1_C  193 ewlrrktlqiLkvllqeidlrkpaeisslgsdllspllrlletelcseALeVLdevvsvsg 253 
                   +w+r+k+l+iL+vl++e+d+r+p ei+s+g+dl+spllrll+telc++ALeV+d++++vsg
   EEA21449.1 2193 QWFRIKILSILSVLIPEMDMRRP-EITSHGPDLISPLLRLLQTELCPQALEVMDHIMTVSG 2252
                   *********************99.**********************************996 PP

>> MOR2-PAG1_mid  Cell morphogenesis central region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.8   3.4   9.2e-10   4.1e-06       7     443 ..     998    1473 ..     995    1481 .. 0.75
   2 !   40.9   0.4   1.3e-14   5.7e-11     488     747 ..    1481    1754 ..    1474    1761 .. 0.82
   3 !   45.8   0.5     4e-16   1.8e-12     924    1093 ..    1788    1956 ..    1771    1970 .. 0.77

  Alignments for each domain:
  == domain 1  score: 24.8 bits;  conditional E-value: 9.2e-10
  MOR2-PAG1_mid    7 seldavgliflssvdvqirhtalellrcvralkndlrdlsvkersdsklknekepifiidvleengddivqscywdsgrpydlrresdavpsdv 100 
                      e++a g+ fl+s   ++r+ a+ +lr v  + n l +   + r       e++   i+d+ +e    i ++   + g     +r s +  + +
     EEA21449.1  998 EEIEAHGIFFLCSQSRRVRRFAISVLRLVTEFDNALGK--ENTR--IIRILEADSHQIMDLNDEH-LTIAERSRLQKG-----KRRSTSQNTLI 1081
                     5899*******************************998..3333..3444566667788987665.457776666666.....56666666777 PP

  MOR2-PAG1_mid  101 tlqsilesadksrwarclselvkyaaelcpssvqear................levvqrlaqitpvelg.gka..kqsqdteskldqwllyamf 175 
                      l s   s d s w +++ ++++ + + cp +v  ar                l   qrl+q ++ ++  g++  +    +e  ++qw ly ++
     EEA21449.1 1082 ELCSSDVSYDSSLWVKVFPNIIRVSFDTCPVAVTLAReivcarlvqmhrnittLAESQRLQQYATFDMTqGRSlgRARSPAEIMIEQWKLYLLM 1175
                     888888899****************************9999999999999988888999*999999885355522344568999********** PP

  MOR2-PAG1_mid  176 acscppd..........sre............dsalkaakelyhlilpslksgseakikaatlalghshlevceimlgelasfleevasetesk 247 
                     ac+   +          + e            + ++ +a+ l+ +++p l    ++   a   alg     +   +l  l+  +     e + +
     EEA21449.1 1176 ACTTLSNvgaqsqsqlaNAEharrtskgmqtaQDKIGSARALFAFVIPLLSASLDSIRDAIVSALGSINKALYRTLLESLQYAVTTCNEEAKLR 1269
                     **864321111111111111111111111111335668899*********999999999*********99999999999988887666665544 PP

  MOR2-PAG1_mid  248 pkw......ksqkarred.lrvhvaniyrmvaeniwpgmlsrkpvlrlhflkfieetvrqiltspsenfqdlqplryalasvlrslapelvdsk 334 
                                +++r+ d lr+ v+ +y++ +  +    +     +   ++ + ++    +  + ++n  ++q lr   + ++  l   +  +k
     EEA21449.1 1270 IGThnrtpsSPHRSRKTDrLRTEVTHVYKLTSIFLREAEIFNDDWIVNNLVTYAKDLRLFLSDAEVQNDWEFQRLRNHYCGLMEELFEGINRTK 1363
                     33344445344567765449************99999999999888889999999988888889999999*************99987776655 PP

  MOR2-PAG1_mid  335 ..serfdsrtrkrlfdlllswsddtgstwsqdgvsdyrreverykasqnsrskdsvdklsfdkevaeqleaiqwvamnalaallygpcfddn.. 424 
                       s  +    rk  f l+  w+  +    sq   ++   ++ r+  +q++   d  +  ++  e+  + + +q +a+ a+++l  gp       
     EEA21449.1 1364 epSRWMPFESRKSAFSLMEGWCGYSP---SQAQIAQREDNMRRFAIAQHNDPGDLRNPAAL-IEI--EKKNLQSAALSAMSSLCAGPISTTTeg 1451
                     2255667789************7765...57777777888999999**9998887666555.333..34578999************8654311 PP

  MOR2-PAG1_mid  425 ..arkl.sgrviswinslflep 443 
                       + ++   r++ wi s+f   
     EEA21449.1 1452 gsILQFdVSRMLVWIGSIFETV 1473
                     1122222479999999999765 PP

  == domain 2  score: 40.9 bits;  conditional E-value: 1.3e-14
  MOR2-PAG1_mid  488 akvalknllqtnld...lfpacidqcyssda......siadgyfsvlaevymrqeipkceiqrllslilykvvdqsrkirddalqmletlsvre 572 
                      + alknl+  n +   l+   id cy  d          + yf v+ +v + +    +   r++++++y + +++r ir +a+++   l  r+
     EEA21449.1 1481 GRRALKNLIVHNKEypfLLERMIDLCYGVDRdrrlgdKALESYFEVVNQVLIEETDYAVAFWRVVAVVMYMLGNEKRDIRMKAVKLTRILEERQ 1574
                     6789*****9998755578899*****887522111124478***********9999****************************999887776 PP

  MOR2-PAG1_mid  573 waedgeegagryraavvgnlpdsyqqfqyklsaklakdhpelsellceeimqrqldavdiiaqhqvltcmapwienlnfl...klkesgwserl 663 
                          +     +  ++  +    y+  q+++s +la ++ ++  l+  e  +    ++    q +v+t + pw++ +++    + + +  s  l
     EEA21449.1 1575 QK---NSRLQDFDISLSDKTTAVYKLAQFEISKRLASQYSDIGFLIFSEFSRHFTRTMSTDDQRNVVTAILPWVQAMELQvdpNQQPTPRSYML 1665
                     54...45688999*************************************99999999999**************998762223445678899* PP

  MOR2-PAG1_mid  664 lkslyyvtwrhgdqfpdeieklwstvaskrr..niipvldflitkgiedcdsnas...aeitgafatyfsvakrvslylaricpqqtid 747 
                     l  +  +t      +p+e++ lw+++a+ ++  n+  +ldf+i+  +e  + n      +i   +++  + +k + ++l  ++p+  i+
     EEA21449.1 1666 LVNMLEITILRCKLLPNEVQALWQSLATGPHggNVQVILDFIISLCLERKEQNFVeyaKQIVVFLSSTPAGSKVIEFFLLHVAPKYMIQ 1754
                     ***************************9875559*************998887531102333333444445788888888888887775 PP

  == domain 3  score: 45.8 bits;  conditional E-value: 4e-16
  MOR2-PAG1_mid  924 lsradialillaeiayendedfrehlpllfhvtlvsmdssedivlkhcqdllvnllyslagrhlelyevessdgenkqqvvslikyvqskrgsl 1017
                     ls  ++++i+l ++         +++  l+hv l+  d     v ++ +++lv l++ l   +l+    ++  +e +q +  ++  ++    s+
     EEA21449.1 1788 LSMGQLSMIFLVDLIVGPVTLAVQDVIKLLHVVLILWDHYTFTVQEQAREMLVHLIHELVSSKLQ----DEVSTEARQAIEHFVDSIRKSDASV 1877
                     566666666666666665555566677899******************************99986....5667888999999999999999*** PP

  MOR2-PAG1_mid 1018 mwenedatlvrte....lpsaallsalvlslvdai.ffqgdlrekwgaealkwamectsrhlacrshqiyralrpsvtsdt 1093
                     +we ed      +    +p a  ++ + + +v+ + +   d+ + w +eal+wa  c  rhlacrs q++r++  s++ + 
     EEA21449.1 1878 IWEYEDNHGKEEDdgtrVPPA--MTFVTRQVVQFLnLVHEDISDLWSKEALNWATSCPVRHLACRSFQLFRCISKSLEPKM 1956
                     *****9876554311114544..33344555555425689*******************************9988876655 PP

>> Inhibitor_I9  Peptidase inhibitor I9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   2.1   0.00028       1.2      15      72 ..     225     281 ..     201     285 .. 0.67

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00028
                   HHHHHHHHHH....HHHHTT...--EEEEEEESSSSSEEEEEE-GGGHHHHHTSTTEEE CS
  Inhibitor_I9  15 kassheswhqsllksvlkge.dsakagilysYkilfnGfavklteeqaeklrkrpeVes 72 
                   ++s++++ h+  ++++ ++  ++ak+  +y  ++lfn+f ++ +++  + + k  eVe+
    EEA21449.1 225 SNSKLRREHS--HSRTHSKHhQEAKTVGEYALHHLFNSFVAHADNKINQSIVKVGEVEA 281
                   2344444444..2223333355778888999999*************999999999985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2620 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       814  (0.0454013); expected 358.6 (0.02)
Passed bias filter:                      567  (0.0316247); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.33u 0.35s 00:00:01.68 Elapsed: 00:00:00.54
# Mc/sec: 14607.49
//
Query:       EEA21450.1  [L=240]
Description: endoglucanase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.6e-12   45.7  14.4    4.6e-12   45.7  14.4    3.0  2  CBM_1           Fungal cellulose binding domain
      3e-08   33.8   0.7    8.5e-08   32.4   0.7    1.8  1  DPBB_1          Lytic transglycolase


Domain annotation for each model (and alignments):
>> CBM_1  Fungal cellulose binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   3.9       1.8   1.6e+04      12      20 ..      55      63 ..      53      70 .. 0.65
   2 !   45.7  14.4   5.2e-16   4.6e-12       2      29 .]     208     235 ..     207     235 .. 0.98

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 1.8
       CBM_1 12 GpTtCvsga 20
                G+T C +g 
  EEA21450.1 55 GATWCGAGC 63
                777777763 PP

  == domain 2  score: 45.7 bits;  conditional E-value: 5.2e-16
       CBM_1   2 wgQCGGigWtGpTtCvsgatCtyqNeyY 29 
                 +gQCGG+gWtG+TtC++g+tC++ N++Y
  EEA21450.1 208 YGQCGGSGWTGATTCAAGSTCHQANQWY 235
                 **************************** PP

>> DPBB_1  Lytic transglycolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.4   0.7   9.5e-12   8.5e-08       1      62 [.      43     123 ..      43     128 .. 0.74

  Alignments for each domain:
  == domain 1  score: 32.4 bits;  conditional E-value: 9.5e-12
                 XEEEEEEE-CCC......-TTSSB--TTS-EEE-SSS-TT-EEEE.TT.--EEEEEEEE----................STTECEE CS
      DPBB_1   1 taagsaslykdg......tacGecyevkcltaahktlplgtycrv.ls.gksvtVtitDrgpf................ppgrhiD 62 
                 taags+++++ +      ++cG+cy+++   + ++  + g  c   ++ gks++V++t+ +p+                  ++h+D
  EEA21450.1  43 TAAGSQAFFDTAgatwcgAGCGKCYNLTS--TGNPP-CNG--CGAgGAaGKSIIVMVTNLCPYngnqqwcpevgstnqyGYSYHFD 123
                 689******555589999*********99..55555.344..5556678**************76666666665555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (240 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       738  (0.0411624); expected 358.6 (0.02)
Passed bias filter:                      269  (0.0150036); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 1614.38
//
Query:       EEA21451.1  [L=57]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (57 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       688  (0.0383736); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.43
# Mc/sec: 399.14
//
Query:       EEA21452.1  [L=222]
Description: carbonate dehydratase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.2e-27   95.1   0.3      7e-27   94.6   0.3    1.1  1  Pro_CA    Carbonic anhydrase


Domain annotation for each model (and alignments):
>> Pro_CA  Carbonic anhydrase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.6   0.3   3.9e-31     7e-27       1     150 [.      68     210 ..      68     214 .. 0.86

  Alignments for each domain:
  == domain 1  score: 94.6 bits;  conditional E-value: 3.9e-31
                 EEEEEETTTTS-HHHHT.TS-TTSEEEEEETTG---TT-HHHHHHHHHHHHTS--SEEEEEEETT-HHHHHHHSHHCCSTTSSHHHHHHHHHHHHHHHC CS
      Pro_CA   1 alvigCsDSRvppelit.dagpGdlFvvrnvgnlvppadssvlaaleyAvevlkvkhivVlGHskCGavkaalkaekseeeagaidkwlekirealekv 98 
                 +l++gCsDS + +++ + +    ++ vvrn gn+  ++d + ++a++ Ave l+vkhi+V+GH++CG vk+  +  +   +++    w +ki +  +++
  EEA21452.1  68 ILWLGCSDSGYEETTTLnNLLEDEMIVVRNWGNMALSTDLAWASAVQHAVEMLGVKHIIVCGHYGCGIVKT--D--S---ATNSAYPWQKKISTLCSAH 159
                 59*********9887772566789**********************************************2..2..2...2357889************ PP

                 HHHHHTTSSHHHHHHHHHHHHHHHHHHHHHCSHHHHHHHHTTS-EEEEEEEE CS
      Pro_CA  99 eeelesekekearerlleeenVaeqlenLlekpvvreavekgklkvhGlvyd 150
                 ++ele+   +++r++ l+e+nV +q+e +++   + +  ++++++vhG +yd
  EEA21452.1 160 QHELECLA-DSERNKHLVELNVIKQMEGVRDLLDIVSPEKNRRITVHGFIYD 210
                 *9999986.55556666***************55555778899********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (222 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       419  (0.02337); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1493.75
//
Query:       EEA21453.1  [L=694]
Description: NADPH cytochrome P450 reductase (CprA), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.2e-65  220.3   0.0    3.3e-65  219.8   0.0    1.3  1  FAD_binding_1  FAD binding domain
    1.6e-34  119.2   1.0      3e-34  118.3   1.0    1.5  1  Flavodoxin_1   Flavodoxin
    7.4e-21   74.8   0.0    6.5e-20   71.8   0.0    2.4  2  NAD_binding_1  Oxidoreductase NAD-binding domain


Domain annotation for each model (and alignments):
>> FAD_binding_1  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  219.8   0.0   5.5e-69   3.3e-65       2     222 .]     272     490 ..     271     490 .. 0.98

  Alignments for each domain:
  == domain 1  score: 219.8 bits;  conditional E-value: 5.5e-69
                    --BTTB-EEEEEEEEEE---.-SS--EEEEEEE-TTBT----TT-EEEE-----HHHHHHHHHHHT--T..T-EEEEEESSTT..S--SSSSSEEH CS
  FAD_binding_1   2 pfdakkvflakvlknreLtkpesernvihveldisdsglkYetGdhlgvypsNneelVeellellgldpkadevvelkaldeesaekeprleptTl 97 
                    p +a+++++a+++++reL+   ++rn++h+e dis+sgl+Y+tGdh++v+p N   +V+ +l+++gld+k+++v+++k ld   + k p++ ptT+
     EEA21453.1 272 PYSAHNPYIASIAESRELFT-VKDRNCLHMEVDISGSGLHYQTGDHIAVWPTNAGLEVDRFLKVFGLDAKRETVIKIKGLD--VTAKVPFPAPTTY 364
                    67899***************.9***********************************************************..69*********** PP

                    HHHHHHTB--SS---HHHHHHHGGG-SSHHHHHHHHHHHH-..HHHHHTTTTT--HHHHHHHHHTT---TTS-HHHHHHHS-B---EEEEB-S-TT CS
  FAD_binding_1  98 rqalkyylditgppskqlleaLaefaseeeekqkLekLssd..egakeykelklneartllevleefpsvklplefLlevlpqLkpRyYSiSsssk 191
                    ++a++yy++i+ p+s+q+++ La fa++e+ k+++ +L++d  ++++++++  +n a++l  v+  +p++++p++ L+e + +++pRyYSiSsss 
     EEA21453.1 365 DAAVRYYMEICAPVSRQFVSTLAAFAPDEKAKAEMVRLGNDkdYFHEKISSQCFNIAQALESVS-TAPFSAVPFSCLIEGINRIQPRYYSISSSSL 459
                    ****************************************999*****************9997.58***************************** PP

                    TTTTEEEEEEE--EE---SSS--EE-HHHHH CS
  FAD_binding_1 192 vhpdevhltvvVveyetdgegrirkGvcsny 222
                    v+++++ +t+vV++++  g  +++kGv++ny
     EEA21453.1 460 VQKEKISITAVVESVRIPGATHLVKGVTTNY 490
                    *****************99**********98 PP

>> Flavodoxin_1  Flavodoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.3   1.0   5.1e-38     3e-34       1     143 []      67     215 ..      67     215 .. 0.96

  Alignments for each domain:
  == domain 1  score: 118.3 bits;  conditional E-value: 5.1e-38
                   EEEETSSSHHHHHHHHHHHHHHH.TTTEEEEEEEEGTTSC.GGGGGTHSEEEEEEEEETTTBEEGGGHHHHHHHHHHHCHH......GCCSTTTTEE CS
  Flavodoxin_1   1 ilYgSetGnteklAkqlaeelge.hgfnadvvslsdydes.lseieeealllvvtsTfgnGdppengesffqdllelkgde......ledgdlsgvr 89 
                   i+YgS+tG++e++A +la+e ++  g++++v +l++yd + l+ ++e++++ ++ +T+g+G+p++n+  +f+++++ +          +d++ls+++
    EEA21453.1  67 IFYGSQTGTAEDYASRLAKEGSQrFGLKTMVADLEEYDLDlLDTFPEDKIAFFILATYGEGEPTDNAV-EFYQFITGEDVSfasgasADDKPLSNLK 162
                   8******************99987899***********99***************************9.999999999666******9999****** PP

                   EEEEEEECTTSSSTTHHHHHHHHHHHHTTCEEESSSEEEETTSTHGHHHHHHHH CS
  Flavodoxin_1  90 favfglGdsayenFcaagkkldekleelGaerllkllegdednqegqeeafrkW 143
                   +  fglG+ +ye+++a+++++d+ l++lGa+r+   +egd+    ++ee+f +W
    EEA21453.1 163 YVTFGLGNNTYEHYNAMVRQVDTALTKLGAKRIASAGEGDDGA-GTMEEDFLAW 215
                   *****************************************99.899****999 PP

>> NAD_binding_1  Oxidoreductase NAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.31   1.9e+03      17      38 ..      53      75 ..      50      98 .. 0.77
   2 !   71.8   0.0   1.1e-23   6.5e-20       1     107 [.     546     656 ..     546     658 .. 0.91

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.31
                   HHHHH.CTTCSEEEEEEEESSGC CS
  NAD_binding_1 17 ailee.akdktkvvlvyGnrtee 38
                   +i+e+ ++  +++v++yG +t  
     EEA21453.1 53 NIVEKlDETGKNCVIFYGSQTGT 75
                   566765667899******99865 PP

  == domain 2  score: 71.8 bits;  conditional E-value: 1.1e-23
                    EEEEGGGGHHHHHHHHHHHHHCT...TCSEEEEEEEESSGC.GSTTHHHHHHHHHHCTTEEEEEEEESSCTTTSSSEESSHHHHHHHHHHH...HS CS
  NAD_binding_1   1 miagGtGiaPvrsvlraileeak...dktkvvlvyGnrtee.dllyreeleelakklpgrlkvvavvsreeagweggkgrvqdalleells...lk 89 
                    mi++GtG+aP+r++++++++ a      +++vl++G+r++  d+ly++e+++++++l +++k++++ sre a++    ++vq++l+e+++    l 
     EEA21453.1 546 MIGPGTGVAPFRGFVQERAAMAArgdAVGPTVLFFGCRKSTeDFLYKDEWKAYEEQLGENFKLLTAFSREGAEK----VYVQHRLRENAAYinkLL 637
                    9***************998874457788**********9988************************99999986....*********999888888 PP

                    STTEEEEEEC.SHHHHHHH CS
  NAD_binding_1  90 keethvyvCG.ppgMikav 107
                    ++++ +yvCG +  M++ v
     EEA21453.1 638 EQKAYFYVCGdAAHMAREV 656
                    9*********999999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (694 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       420  (0.0234257); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.63u 0.32s 00:00:00.95 Elapsed: 00:00:00.47
# Mc/sec: 4410.37
//
Query:       EEA21454.1  [L=577]
Description: RNA binding protein MSSP-2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-23   82.1   0.0    3.3e-12   46.1   0.0    2.4  2  RRM_1     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.1   0.0   1.8e-16   3.3e-12       1      58 [.     242     300 ..     242     306 .. 0.96
   2 !   33.8   0.0   1.2e-12   2.2e-08       1      61 [.     330     390 ..     330     400 .. 0.92

  Alignments for each domain:
  == domain 1  score: 46.1 bits;  conditional E-value: 1.8e-16
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHH CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlea 58 
                 ++++++pp++t+e+L+++ s fG+i ++k + d  tg  kgfafV+F + e+ e++++ 
  EEA21454.1 242 VYIRGFPPETTDEMLHAYASRFGEIDRCKAIVDlDTGLCKGFAFVQFYNFESCENCIRG 300
                 8*******************************************************985 PP

  == domain 2  score: 33.8 bits;  conditional E-value: 1.2e-12
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTT CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealng 61 
                 ++++n+p + +e +L+++F+++  + s k++rd +tg sk ++f +Fes+e Ae+ +e++++
  EEA21454.1 330 IYCTNVPIEWSEADLRRHFEPYRVV-SEKISRDeKTGVSKEVGFARFESREIAERVVEEFHN 390
                 89********************888.99******************************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (577 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       359  (0.0200234); expected 358.6 (0.02)
Passed bias filter:                      291  (0.0162307); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.27s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 3750.86
//
Query:       EEA21455.1  [L=213]
Description: DnaJ domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.6e-13   49.9   2.8    3.9e-13   49.3   0.3    2.6  3  DnaJ        DnaJ domain


Domain annotation for each model (and alignments):
>> DnaJ  DnaJ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0      0.14   2.5e+03       9      21 ..      20      32 ..      18      33 .. 0.84
   2 !   49.3   0.3   2.2e-17   3.9e-13       1      63 []      35      96 ..      35      96 .. 0.97
   3 ?   -2.3   0.0      0.28   4.9e+03      50      59 ..     133     142 ..     117     145 .. 0.58

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.14
                STTG-HHHHHHHH CS
        DnaJ  9 skdasedeIkkaY 21
                +kda+ d I+ka+
  EEA21455.1 20 DKDAEIDRIRKAF 32
                6889999999997 PP

  == domain 2  score: 49.3 bits;  conditional E-value: 2.2e-17
                HHHHHHTSSTTG-HHHHHHHHHHHHHHHSTTTSCCHHHHHHHHHHHHHHHHHHTSHHHHHHHH CS
        DnaJ  1 dyYeiLgvskdasedeIkkaYrklalkyHPDknpkdpeaeekFkeineAyevLsdpekRkqYD 63
                d Y++L +++   +++Ik +Yrk++l +HPDk  ++p a ++F ++++A  +L d++ R++ D
  EEA21455.1 35 DAYAVLDLQPGVPDSDIKLQYRKKSLLIHPDKT-QNPLAPDAFDRLKKAQTTLLDEKARERLD 96
                68*******************************.*************************9876 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 0.28
                 HHHHTSHHHH CS
        DnaJ  50 yevLsdpekR 59 
                  evL ++e R
  EEA21455.1 133 IEVLLEDEAR 142
                 4555444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (213 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1749  (0.0975515); expected 358.6 (0.02)
Passed bias filter:                      452  (0.0252106); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.29s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 1441.60
//
Query:       EEA21456.1  [L=819]
Description: DEAD box RNA helicase (Hca4), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.8e-48  163.2   0.2    1.2e-47  162.0   0.0    1.8  2  DEAD        DEAD/DEAH box helicase
    6.7e-24   84.4   0.0      3e-23   82.3   0.0    2.2  2  Helicase_C  Helicase conserved C-terminal domain
    1.6e-21   76.3   0.1    5.2e-21   74.6   0.1    2.0  2  DUF4217     Domain of unknown function (DUF4217)
    1.9e-07   31.3   0.2      6e-07   29.6   0.0    2.0  2  ResIII      Type III restriction enzyme, res subunit
  ------ inclusion threshold ------
        1.9    8.9   4.2        5.3    7.4   4.2    1.7  1  Dsh_C       Segment polarity protein dishevelled (Dsh) C term


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  162.0   0.0   3.3e-51   1.2e-47       1     175 [.      73     242 ..      73     243 .. 0.97
   2 ?   -3.4   0.0         2   7.1e+03      46      93 ..     392     437 ..     380     445 .. 0.66

  Alignments for each domain:
  == domain 1  score: 162.0 bits;  conditional E-value: 3.3e-51
                 -HHHHHHHHHHHTTCEEEEEESTTSSHHHHHHHHHHHHHHHS..TTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   1 tdiQaeaiplilgggdvlvaaeTGsGKTlaflipvlqivyet..kgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldng 97 
                 tdiQ+++ip +l+g+d+l+aa+TGsGKTlaflipvl+++y++  ++ +g  a++++PtreLa q+++ l+k++ y + ++ l+igg++ ++++++l  +
  EEA21456.1  73 TDIQSRSIPYALKGRDILGAAKTGSGKTLAFLIPVLENLYRKkwTEYDGLGAIVLSPTRELAIQIFEVLRKVGRYHTFSAGLVIGGKSLKEEQERL-GR 170
                 89***************************************988899****************************9999*****************.99 PP

                 CSEEEEEHHHHHHHH.HCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHHHH CS
                 xxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  98 vdivvgtpgrlddll.stgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlpkdvkk 175
                 ++i+v tpgr++++l +t +l++ ++++lVlDEadr++d+gf++++++i+++l       +++rq++++SAT +k+v++
  EEA21456.1 171 MNILVCTPGRMLQHLdQTAELDVYNLQMLVLDEADRIMDMGFQKTVDAIVEHL-------PKTRQTLLFSATQTKKVSD 242
                 ***************88999*********************************.......67889*********99887 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 2
                 TS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEE.EEETTSSHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxx RF
        DEAD  46 tgpkalivePtreLaeqtlnnlkkfkkyidlrvl.liiggvaardqlsk 93 
                 +g  +l++ P++e  e +l++l++ k +i+ r++    ++++ +dql++
  EEA21456.1 392 NGRAVLFLDPSEE--EGMLKRLEQKKVPIE-RINvKAKKQQSVKDQLQN 437
                 5566677777776..778888888888777.333134456666777665 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0       2.8     1e+04       6      30 ..     219     241 ..     214     258 .. 0.64
   2 !   82.3   0.0   8.4e-27     3e-23       2     110 ..     280     389 ..     279     390 .. 0.89

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 2.8
                 HHHHHHHTTTTSEEEEEESSHH.HHH CS
  Helicase_C   6 llellkleeeggkilifvntid.rle 30 
                 ++e l    +++++l+f+ t++ +++
  EEA21456.1 219 IVEHL---PKTRQTLLFSATQTkKVS 241
                 44444...678899999988875443 PP

  == domain 2  score: 82.3 bits;  conditional E-value: 8.4e-27
                 HHHHHHHHHHHTTTTSEEEEEESSHHHHHH.HHHHHHHT.TSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSSHH CS
  Helicase_C   2 kleallellkleeeggkilifvntidrlek.vklllekk.gikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprnvt 98 
                 kl++l  ++ +++ ++k+++f+ + +++    + l++ + gi  + lhg+ +q  r++i ++f + ++ vL +tdva+rG+d+p v+ Vi++d+p++ +
  EEA21456.1 280 KLDTLFSFI-RSNLKSKTIVFMSSGKQVRFvYESLRHLQpGIPLLHLHGRQKQGGRLDITTRFANSKHAVLFSTDVAARGLDFPAVDWVIQLDCPEDAD 377
                 777777887.889999**********88556455544446***********************999999****************************** PP

                 HHHHHHTTSSST CS
  Helicase_C  99 syiqriGRtgRa 110
                 +yi+r+GRt+R+
  EEA21456.1 378 TYIHRVGRTARY 389
                 ***********7 PP

>> DUF4217  Domain of unknown function (DUF4217)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.6   0.1   1.4e-24   5.2e-21       2      61 .]     432     491 ..     431     491 .. 0.97
   2 ?   -3.4   0.0       3.4   1.2e+04      37      52 ..     800     816 ..     793     817 .. 0.74

  Alignments for each domain:
  == domain 1  score: 74.6 bits;  conditional E-value: 1.4e-24
     DUF4217   2 qqkleslcakdrdlkelAqkAfvsyvraYsvhlake..iFrvkkLdlealAksfGLleaPki 61 
                 +++l+++c+kd++lk+l+qkAf+syv+  s h +k+  +F+vk+L l+a+A+s+GL++aP+i
  EEA21456.1 432 KDQLQNMCFKDPELKYLGQKAFISYVK--SIHVQKDkeVFKVKDLALDAFAASLGLPGAPRI 491
                 79*************************..******999**********************97 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 3.4
     DUF4217  37 eiFrvkkL.dlealAks 52 
                 e ++v++L dlealA+ 
  EEA21456.1 800 EPLEVNTLeDLEALATG 816
                 46778888899*99975 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.6   0.0   1.7e-10     6e-07      28     168 ..      90     235 ..      66     238 .. 0.88
   2 ?   -3.5   0.2       2.4   8.8e+03      90      96 ..     711     717 ..     674     744 .. 0.53

  Alignments for each domain:
  == domain 1  score: 29.6 bits;  conditional E-value: 1.7e-10
                 EEEESTTSTHHHHH.HHHHHHH-S.........-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--.......-SEEEEEHHHHHHTH... CS
      ResIII  28 likmaTGtGKTlva.aklierllkkgkee....kflflvprkslleqtleefkkflseaykeigkkvsgdkkkakekdstnkkilvttiqsldadseee 121
                 l ++ TG+GKTl   + + e+l++k++ e     +++l p+++l  q  e ++k+   ++ ++g ++ g++ k+++++   ++ilv t  ++ +++   
  EEA21456.1  90 LGAAKTGSGKTLAFlIPVLENLYRKKWTEydglGAIVLSPTRELAIQIFEVLRKVGRYHTFSAGLVIGGKSLKEEQERLGRMNILVCTPGRMLQHL--- 185
                 55678*******99899********9999**************************998888899999999999989999*****************... PP

                 .....HHHTTT-SEEEEETGGGTTS....TTTHHHHHT---.SEEEEEESS CS
      ResIII 122 eeeseellrdrfdviiiDEaHrlgak...kswreilekfke.avllglTAT 168
                   ++ el+  + ++++ DEa r+ ++   k++ +i+e++++    l ++AT
  EEA21456.1 186 -DQTAELDVYNLQMLVLDEADRIMDMgfqKTVDAIVEHLPKtRQTLLFSAT 235
                 .667777777888************98877999999999553777999999 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 2.4
                 SSS-B-- CS
      ResIII  90 sgdkkka 96 
                  ++kk++
  EEA21456.1 711 AKQKKRE 717
                 1111111 PP

>> Dsh_C  Segment polarity protein dishevelled (Dsh) C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   4.2    0.0015       5.3      90     148 ..     718     795 ..     694     814 .. 0.69

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0015
       Dsh_C  90 reaskeekerkag...........................gsgsesesstrssvsrrerekaqserssaaaserskrssklrskss 148
                 +++++++     +                           gsg+ese  ++     + +++ + e++ ++ s++skrs+k    ++
  EEA21456.1 718 KKEKRKA-----KeralaegedgvavlagdeefidpfqsnGSGAESEADEEMPKLSKGMKHVSVEEEEENDSRKSKRSKKS---HK 795
                 1111112.....12234466888889999999999999999****999988888788888888888888889999988332...22 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (819 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1702  (0.09493); expected 358.6 (0.02)
Passed bias filter:                      593  (0.0330749); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.84u 0.34s 00:00:01.18 Elapsed: 00:00:00.50
# Mc/sec: 4880.14
//
Query:       EEA21457.1  [L=538]
Description: amino acid permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   3.9e-130  434.7  41.4   4.4e-130  434.5  41.4    1.0  1  AA_permease    Amino acid permease
    2.3e-42  145.4  47.8    2.8e-42  145.0  47.8    1.1  1  AA_permease_2  Amino acid permease
  ------ inclusion threshold ------
        5.2    7.2   5.9         12    6.1   0.1    3.0  2  DUF3671        Protein of unknown function


Domain annotation for each model (and alignments):
>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  434.5  41.4  7.4e-134  4.4e-130       2     476 ..      37     487 ..      36     490 .. 0.97

  Alignments for each domain:
  == domain 1  score: 434.5 bits;  conditional E-value: 7.4e-134
  AA_permease   2 vlvialggviGtglfvglgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgpelGfviGlnylfswitvlaleltaasi 99 
                  v++ia++g iGtglf+g+g+ l+++Gp+++l++y+++g++++++ml+lge++ ++p++g+f t+a rf+++++Gf+  +ny+f++++  a +l+a++ 
   EEA21457.1  37 VQMIAIAGTIGTGLFLGTGNSLAKGGPASMLISYAIVGAIVYITMLALGEMSAFIPVAGSFCTFAGRFVDDAFGFALTWNYWFNDAVSTASDLIALQL 134
                  9************************************************************************************************* PP

  AA_permease 100 liqfwelvtdlpkawvtgavflvvlliinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkga.gfrflgdngsifknnlppgfakeeeg 196
                  l+q+w  ++  p  w+++++fl+v++++n+++v++ygeae+il+++k+++i++fi++gi++++gg++++++ g+r+++    i ++ +++g       
   EEA21457.1 135 LLQYW--TDNFP-GWAISLIFLFVVIGLNVISVRAYGEAEYILSILKVVTIVIFIVLGIVVNCGGNTSHQYiGGRNWH----IGDAPFVGG------- 218
                  *****..66666.*********************************************************77777776....5566*****....... PP

  AA_permease 197 afknfisvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasaaspfvifikesgvsvlaplina 294
                   + +f+svfv+++fa+ G+e++a++agE+kdP+k++P+++++v++ri+ifY+l++l+igl vp+n++gl ++   + spf i+++ +g++v++++ina
   EEA21457.1 219 -IGGFASVFVTASFAYGGTESIAVTAGETKDPAKNLPRVVRNVFWRILIFYILAVLIIGLNVPYNYPGLRTKNSHT-SPFTIVFEQAGSRVAGSFINA 314
                  .*********************************************************************966666.********************* PP

  AA_permease 295 viltaalssansslysasRvlyslakdglaPkvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliilsylrfRk 392
                  v+ t+++s++n +l+++sR+lysla dg+aP++++++++++vP++a+l++++is l++ ++++ ++  + +++l +i+++++ + w++i++s+lrfR 
   EEA21457.1 315 VVMTSVISAGNHALFAGSRLLYSLATDGYAPSFFARLNRQKVPWVAVLATSVISGLCFGASYIGAG--QLWTWLQNIVGVSNQLSWIAICFSSLRFRA 410
                  **********************************************************88888888..****************************** PP

  AA_permease 393 alkyqgrsieelgfkaallplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfliilvgvklhvknkrpq 476
                  a+k+qg  + +l+fk +++p+g+i++++++i ++l++++  + +       + a++f++ y+ +++++++++ +k+ +++++ +
   EEA21457.1 411 AIKKQGLEH-LLPFKNWTYPYGPIIAMILNIVLVLVQGWSSFSP------IFAAVDFVSYYIEIPVMIVMYLFWKILKRTRFVK 487
                  *******88.********************************99......889*************************999876 PP

>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.0  47.8   4.7e-46   2.8e-42       2     422 ..      33     470 ..      32     476 .. 0.83

  Alignments for each domain:
  == domain 1  score: 145.0 bits;  conditional E-value: 4.7e-46
  AA_permease_2   2 sllsafalvigsvigsgifvkn..laasggpalilwvwiavligslavllvyaElssalprsgGiyvytkaafgkkvaflsawfnwfayvpvlasi 95 
                    s +++ +++i  +ig+g f  +  ++a+ggpa++l+   +v++++++ +l++ E+s+ +p  g   +++ ++    ++f  +w +wf  ++++ ++
     EEA21457.1  33 SARQVQMIAIAGTIGTGLFLGTgnSLAKGGPASMLISYAIVGAIVYITMLALGEMSAFIPVAGSFCTFAGRFVDDAFGFALTWNYWFNDAVST-AS 127
                    66788999***********998889999****998888888888899********************************************99.67 PP

  AA_permease_2  96 lsvaasyllnalgpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfssl......stetdtffpn 185
                      +a++ ll+ +  ++ g+      i  ++l +v+ +n+++++ ++ +  il ilk+ ++++i+i+lg+++ +gg  s +      ++++d  f +
     EEA21457.1 128 DLIALQLLLQYWTDNFPGW-----AISLIFLFVVIGLNVISVRAYGEAEYILSILKV-VTIVIFIVLGIVVNCGGNTSHQyiggrnWHIGDAPFVG 217
                    7777888877786677665.....58889999*************************.6************9997666555666665556667777 PP

  AA_permease_2 186 gwpgvllgllivlwsfdGfesaanvseevkk..kdvpkaifigllivlvlyllvniaflgvvpddei....anlsnlgsvaalffeavggkvvaii 275
                    g  g+++++ ++ ++++G es+a+ + e k   k++p++  +++  +l++y+l  + +   vp ++     +n+++  s+++++fe++g++v+ ++
     EEA21457.1 218 GIGGFASVFVTASFAYGGTESIAVTAGETKDpaKNLPRVVRNVFWRILIFYILAVLIIGLNVPYNYPglrtKNSHT--SPFTIVFEQAGSRVAGSF 311
                    77778999999*****************776669*******************96666666666665776333333..57**************** PP

  AA_permease_2 276 vvilialsllgaintavigssrvlealardgvlPrffakvnkfgspiraiiltaivslillllfllassaaynfllsvsslgliisyllliigali 371
                    ++++++ s++ a+n a+++ sr+l++la+dg+ P+ffa+ n+++ p++a+  t ++s +++ +++++ +   ++l ++  +++ +s++++ ++ l 
     EEA21457.1 312 INAVVMTSVISAGNHALFAGSRLLYSLATDGYAPSFFARLNRQKVPWVAVLATSVISGLCFGASYIGAGQLWTWLQNIVGVSNQLSWIAICFSSLR 407
                    ****************************************************************99989999*****************9999887 PP

  AA_permease_2 372 lrkkrphlkr...........pgkilvaiigalfllfllvalf..fppkgpatqssliyt.iilt 422
                     r   ++++            p  + + i ++l ++++lv ++  f p  +a+ + ++y  i ++
     EEA21457.1 408 FRAAIKKQGLehllpfknwtyP--YGPIIAMILNIVLVLVQGWssFSPIFAAVDFVSYYIeIPVM 470
                    7755444322446655554333..33444444444444444444466667777777777664444 PP

>> DUF3671  Protein of unknown function
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.1    0.0019        12      41     106 ..     164     275 ..     145     279 .. 0.77
   2 ?    1.3   2.1     0.056   3.4e+02      92     113 ..     460     481 ..     423     482 .. 0.75

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0019
     DUF3671  41 lkkyglllilpvllpliglivpilfeaksk..............................................kslkkkelevlatsieklytiff 93 
                 ++ yg    ++++l+++ ++++i+ ++ ++                                              +    ++++ +++  + ++++f+
  EEA21457.1 164 VRAYGEAEYILSILKVVTIVIFIVLGIVVNcggntshqyiggrnwhigdapfvggiggfasvfvtasfayggtesiAVTAGETKDPAKNLPRVVRNVFW 262
                 556666666667777777777777666666777777779999999999999999999999999999999999988755555666677777778899999 PP

     DUF3671  94 iilvviillvliY 106
                  il++ il vli+
  EEA21457.1 263 RILIFYILAVLII 275
                 9999999998885 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.056
     DUF3671  92 ffiilvviillvliYiliKviK 113
                 f++ ++ i +++++Y++ K++K
  EEA21457.1 460 FVSYYIEIPVMIVMYLFWKILK 481
                 5666777778889******998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (538 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       990  (0.0552178); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.34s 00:00:00.96 Elapsed: 00:00:00.50
# Mc/sec: 3251.45
//
Query:       EEA21458.1  [L=568]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00018   21.6  10.6    0.00027   21.0  10.6    1.3  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0  10.6   1.5e-08   0.00027       2      38 ..     182     219 ..     181     221 .. 0.92

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 1.5e-08
                 S-HHHHHCT---STSSSS-HHHHHCT..HHHCCCCTCCC CS
     Zn_clus   2 aCdnCrkkKvKCdakkPaCsnCkkln..leCtfysessk 38 
                 aC nC++k+  Cd  +P C++C+ ++  ++C++ + +++
  EEA21458.1 182 ACVNCKRKHLGCDSARP-CRRCVLSGkaSTCVDVTHKKR 219
                 9****************.********9999*99888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (568 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       652  (0.0363657); expected 358.6 (0.02)
Passed bias filter:                      249  (0.0138881); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 3667.95
//
Query:       EEA21459.1  [L=275]
Description: hypothetical protein PMAA_052690 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-14   54.6   1.1    1.1e-14   54.6   1.1    2.0  2  DUF202    Domain of unknown function (DUF202)
  ------ inclusion threshold ------
      0.078   12.5   1.5       0.12   11.9   1.5    1.3  1  TM140     TM140 protein family


Domain annotation for each model (and alignments):
>> DUF202  Domain of unknown function (DUF202)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.6   1.1   1.2e-18   1.1e-14       1      67 [.      53     124 ..      53     125 .. 0.88
   2 ?   -0.6   0.2      0.22   1.9e+03      34      55 ..     136     156 ..     129     163 .. 0.53

  Alignments for each domain:
  == domain 1  score: 54.6 bits;  conditional E-value: 1.2e-18
      DUF202   1 rdglAnERTfLaWlRtslalialglallrffl.....tgepsalgkilglilivlgiltllvglvrylrrqr 67 
                 rd+lAnERTfL+WlR s++l++++ a+l +f+     t+ + +++ +lg++++ +++++l+ g+  y+ +++
  EEA21459.1  53 RDHLANERTFLSWLRLSIYLAIVSSAILISFHltsipTQLERSIALPLGIVFWCMSLACLASGFGLYVTTVK 124
                 8***************************887777776555555699******************99998876 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.22
      DUF202  34 gepsalgkilgli.livlgiltl 55 
                 g++++  +i+g++  +++g+++l
  EEA21459.1 136 GWKTQ--AIFGVMaTVIIGCCIL 156
                 55555..5666553344444443 PP

>> TM140  TM140 protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   1.5   1.4e-05      0.12      71     143 ..      59     133 ..      49     166 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 1.4e-05
       TM140  71 prvglalarlgvygalvlt.lfvplplllaqcn.kdegeWklavgflaassvllagGlglflsyvwkWvrlsllG 143
                 +r  l+  rl++y a+v + ++++  l    ++ +      l ++f  +s   la+G+gl+++ v+k+ r + l 
  EEA21459.1  59 ERTFLSWLRLSIYLAIVSSaILISFHLTSIPTQlERSIALPLGIVFWCMSLACLASGFGLYVTTVKKYSRKAALV 133
                 56667788999999999751555555443322202233567889999*********************9988764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       543  (0.0302861); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.31s 00:00:00.79 Elapsed: 00:00:00.48
# Mc/sec: 1721.72
//
Query:       EEA21460.1  [L=639]
Description: MATE efflux family protein subfamily, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.9e-60  201.8  36.2    2.3e-35  121.6  13.4    2.6  3  MatE      MatE


Domain annotation for each model (and alignments):
>> MatE  MatE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.6  13.4   1.3e-39   2.3e-35       1     160 [.     208     367 ..     208     368 .. 0.99
   2 !   89.5  11.0     1e-29   1.8e-25       6     159 ..     433     587 ..     428     589 .. 0.96
   3 ?   -2.9   0.1      0.26   4.6e+03      82      98 ..     603     619 ..     590     633 .. 0.59

  Alignments for each domain:
  == domain 1  score: 121.6 bits;  conditional E-value: 1.3e-39
        MatE   1 PialenllesllslidtllvgrlgskalAavsialsilsllfv.fllglstalttlvgqalGaknfkrakealrqglilllllsliiallvllfseqil 98 
                 P+++++ll+++l+ ++++ vg+lg+ +l+avs+a++++s++++ +  gl+t+l+tl++qa+G++++k ++ ++++++++l ++ ++ia++ ++f+++il
  EEA21460.1 208 PLIVTFLLQYSLTVASIFTVGHLGTIELGAVSLASMTVSITGSaVYQGLATSLDTLCAQAYGSGRKKLVGLQMQRMVFFLWVVTIPIAII-WFFADKIL 305
                 99****************************************************************************************.******** PP

        MatE  99 slftqdeevlelakrylrililgipalalqlvlsgilrgagktkvplyislislllniplny 160
                   +  + ev+ la+ryl++li+g+p++a+++  +++++++g++ ++ly++li+++ln+ +n+
  EEA21460.1 306 VAIIPETEVALLAARYLKVLIFGAPGYACFESGKRFVQAQGIFTASLYVLLICAPLNAFMNW 367
                 ************************************************************98 PP

  == domain 2  score: 89.5 bits;  conditional E-value: 1e-29
        MatE   6 nllesllslidtllvgrlgskalAavsialsilsllfvfllglstalttlvgqalGaknfkrakealrqglilllllsliiallvllfseqilslftqd 104
                 + +e l + ++tl+ ++lg++alAa s+ ++i+s++f +++ +++a +t+v++ +Ga  +++a++a+ ++l  +++++l+ +ll+ l+++ ++ lft+d
  EEA21460.1 433 VEAECLAFEVLTLVSSYLGTEALAAQSVLSTISSITFQIPFPVAIAGSTRVANLIGATLVDAARTAAKVALTGAVIVGLLNMLLLSLLRHSLAGLFTSD 531
                 556778899****************************************************************************************** PP

        MatE 105 eevlelakrylrililgipalalqlvlsgilrgagktkvplyislisl.llnipln 159
                 eev+e+++ +l+i + +++++al   ++gilrg g+++++ y+ ++++ ++ +p++
  EEA21460.1 532 EEVIEMVAAILPICAAFQLFDALAANCNGILRGLGRQEIGGYVQVFCYyVVAMPIS 587
                 ***************************************************99985 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 0.26
        MatE  82 lsliiallvllfseqil 98 
                  ++++al +++f+e+i+
  EEA21460.1 603 TGVALALGLVFFIEIIF 619
                 33444444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (639 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       694  (0.0387082); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.25s 00:00:00.81 Elapsed: 00:00:00.41
# Mc/sec: 4684.53
//
Query:       EEA21461.1  [L=292]
Description: possible replication factor-a protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-20   74.2   0.0    2.4e-20   73.1   0.0    1.6  1  RPA_C            Replication protein A C terminal
    2.9e-06   27.2   0.4    4.5e-06   26.5   0.4    1.3  1  tRNA_anti-codon  OB-fold nucleic acid binding domain
  ------ inclusion threshold ------
       0.19   11.4   4.6        1.8    8.1   0.3    2.2  2  Chorion_3        Chorion family 3


Domain annotation for each model (and alignments):
>> RPA_C  Replication protein A C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.1   0.0   4.1e-24   2.4e-20       1     103 [.     178     284 ..     178     285 .. 0.83

  Alignments for each domain:
  == domain 1  score: 73.1 bits;  conditional E-value: 4.1e-24
                 HHHHHHHTXXXXXX......XXXXXXXXXXXXXXXXXXXXXXXX.....XSXHHHHHHHHHHHH.SXSTTTEEHHHHHHHSTSXHHHHHHHHHHHHHTT CS
       RPA_C   1 HLeltkgasgssagaagaavavsaggsamgtdgalsgnqaklan....kgltalaqqvlnlikqspeseeGvhvdeiaqklrlsvndvkqavdeLsneG 95 
                 HL+++ g++++++ ++ga + + +gg++ g++++    ++  a     + ++a a++v+nl+k++p+s+eG+h++ i++kl+l+  +v +a deL+++G
  EEA21461.1 178 HLFFKHGPPQKGTDTNGAVSGSGFGGNTAGGMKGDDDYSGAAAGgrplPPMSASARRVYNLLKNEPQSNEGLHMQNISAKLGLPSTEVVKAGDELLSAG 276
                 ************99666666555555555555444444444444566889************************************************* PP

                 SEEESSST CS
       RPA_C  96 iiYsTiDd 103
                 +i+sT+D+
  EEA21461.1 277 LIFSTMDE 284
                 *******9 PP

>> tRNA_anti-codon  OB-fold nucleic acid binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.5   0.4   7.6e-10   4.5e-06       4      65 ..      76     166 ..      73     177 .. 0.85

  Alignments for each domain:
  == domain 1  score: 26.5 bits;  conditional E-value: 7.6e-10
                      EEEEEEEEEEEETTEEEEEEEETTEEEEEEEET................HHHHHHHTTS-TTSEEEEEEEEEECTTS...............S CS
  tRNA_anti-codon   4 aGrvtsisdrsggkvifidlrDgtgriqvvlfr................eeatklaenlkeGdvvrvtGrvkrrpgg...............e 65 
                       G v++i     +  i+++l+Dgtg+i++  +                 + + ++ ++++ + +v+v+G+vk + ++               e
       EEA21461.1  76 IGQVRNI--STQSTNITYKLDDGTGEIEAKQWVdsttarieddmdvdgqGVKHSTRKKVELNGFVKVFGKVKVFGNKrflgahnvrpvsdvnE 166
                      799****..88899************************************************************7765666565655555544 PP

>> Chorion_3  Chorion family 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.5    0.0022        13      17      40 ..      10      33 ..       6     106 .. 0.84
   2 ?    8.1   0.3    0.0003       1.8       9      54 ..     171     224 ..     165     264 .. 0.77

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0022
   Chorion_3 17 sasYGsagggGGkGsgdlgagasa 40
                + sYG++gg GG+G   +  ++ a
  EEA21461.1 10 TTSYGGQGGTGGGGFMPGEVNSPA 33
                689********9997655555444 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0003
   Chorion_3   9 alaaapl........asasYGsagggGGkGsgdlgagasagleelvnaaaGGaa 54 
                 +l a+++         +++  ++g+  G G g  +ag   g +++ +aaaGG  
  EEA21461.1 171 FLEATAIhlffkhgpPQKGTDTNGAVSGSGFGGNTAGGMKGDDDYSGAAAGGRP 224
                 455555555666666566667788888999999999999999**********75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (292 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       379  (0.0211389); expected 358.6 (0.02)
Passed bias filter:                      302  (0.0168442); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 2119.77
//
Query:       EEA21462.1  [L=948]
Description: ATP dependent RNA helicase (Dbp10), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    6.1e-47  159.6   0.0    1.7e-46  158.2   0.0    1.8  2  DEAD        DEAD/DEAH box helicase
    2.7e-23   82.4   0.1    7.8e-23   80.9   0.1    1.8  1  Helicase_C  Helicase conserved C-terminal domain
    3.4e-21   75.2   1.3    3.4e-21   75.2   1.3    3.1  3  DBP10CT     DBP10CT (NUC160) domain
  ------ inclusion threshold ------
      0.063   13.1   0.0        4.6    7.0   0.0    3.3  2  SLS         Mitochondrial inner-membrane-bound regulator


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  158.2   0.0   3.9e-50   1.7e-46       1     173 [.     120     285 ..     120     288 .. 0.96
   2 ?   -2.3   0.0      0.72   3.2e+03      49     104 ..     383     438 ..     371     441 .. 0.55

  Alignments for each domain:
  == domain 1  score: 158.2 bits;  conditional E-value: 3.9e-50
                 -HHHHHHHHHHHTTCEEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTCS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   1 tdiQaeaiplilgggdvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngvd 99 
                 t+iQ+++ip i++++dv++ a+TGsGKT+af+ip+++++ ++ gk g + li++P+reLa qtl+ +k+++  +dl+++l++gg++ ++q   +  ++d
  EEA21462.1 120 TPIQRKTIPVIMDDQDVVGMARTGSGKTAAFVIPMIEKLKSHSGKVGVRGLIMSPSRELALQTLKVVKELGRGTDLKAVLLVGGDSLEEQFGLMVGNPD 218
                 89*************************************999****************************************************888** PP

                 EEEEEHHHHHHHHHCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD 100 ivvgtpgrlddllstgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlpkdv 173
                 iv++tpgr+++l  + +l+ls+++++V+DEadrl ++gf  ++ +il+ l       +++rq++++SATlpk++
  EEA21462.1 219 IVIATPGRFLHLKVEMNLDLSSIKYVVFDEADRLFEMGFAAQLTEILHGL-------PATRQTLLFSATLPKSL 285
                 ***********9988999********************************.......67789********9654 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 0.72
                 EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTT.CSEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxx RF
        DEAD  49 kalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldng.vdivvgt 104
                  ++i + t+  +  +++ l++ +  +++ +   + ++a++ q++++++g ++i+v t
  EEA21462.1 383 STIIFAATKHHVDYIASMLREAGFAVSYAY-GSLDQTARNIQVQRFRAGaTHILVVT 438
                 444445554444444444444444333222.23346777777777777777887776 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.9   0.1   1.7e-26   7.8e-23      15     111 .]     380     476 ..     371     476 .. 0.94

  Alignments for each domain:
  == domain 1  score: 80.9 bits;  conditional E-value: 1.7e-26
                 TTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSSHHHHHHHHTTSSSTT CS
  Helicase_C  15 eggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprnvtsyiqriGRtgRag 111
                  ++ ++if+ t+ +++ +  +l++ g+ v + +g+l q  r+  +++f++g +++L+ tdva+rGidip + +Vin+d+p +++ +++r+GRt+Rag
  EEA21462.1 380 TKHSTIIFAATKHHVDYIASMLREAGFAVSYAYGSLDQTARNIQVQRFRAGATHILVVTDVAARGIDIPILANVINYDFPSQPKVFVHRVGRTARAG 476
                 57899**********98666667779*********************************************************************97 PP

>> DBP10CT  DBP10CT (NUC160) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.6         3   1.4e+04       5      23 ..     351     369 ..     349     378 .. 0.49
   2 !   75.2   1.3   7.7e-25   3.4e-21       1      64 [.     766     830 ..     766     831 .. 0.92
   3 ?   -1.8   0.9      0.83   3.7e+03      15      45 ..     883     912 ..     866     916 .. 0.59

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 3
     DBP10CT   5 Deaeelkkkkqakk.lrWDk 23 
                 D++ee    ++++k +r D+
  EEA21462.1 351 DDEEEED-GRRPRKrKRFDS 369
                 4443333.344444345554 PP

  == domain 2  score: 75.2 bits;  conditional E-value: 7.7e-25
     DBP10CT   1 DLtgDeaeelkkkkqakk.lrWDkKkkkyVkrtnkdedgsk....kirtESGvkiaasfksgrYdkWkk 64 
                 DLt+De+     +++a++ +rWDk++kkyV+r+n dedgs+    +ir+ESG+kiaasf+sgr+d+Wk+
  EEA21462.1 766 DLTADEKA---GFGEAQSsMRWDKRHKKYVSRRN-DEDGSRggsaLIRGESGTKIAASFRSGRFDAWKR 830
                 9******4...4667777789************9.999*999999**********************97 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 0.83
     DBP10CT  15 qakklrWDkKkkkyVkrtnkdedg.skkirtE 45 
                 ++  ++WD  k      ++++e   ++k ++E
  EEA21462.1 883 KK--KKWDAAKDAAAAAAGGNEAAgNRKTKNE 912
                 22..4688766555444433332225666555 PP

>> SLS  Mitochondrial inner-membrane-bound regulator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.0     0.001       4.6      25      87 ..     305     404 ..     300     453 .. 0.76
   2 ?   -0.8   1.8      0.26   1.2e+03      92     147 ..     655     716 ..     652     792 .. 0.57

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.001
         SLS  25 geleevklsprefflLl.tgngklLqnl.....................................srihgakielnrsenklritAtkstaeyieasin 85 
                 g+++  +l++  f+  +  ++g lL+ l                                     s++ g++ e   +++++++ Atk++++yi   ++
  EEA21462.1 305 GKIS-PDLQNAFFTVKTaDKEGALLHILhdvikiptgptgvyfrsneddeeeedgrrprkrkrfdSNKAGKHTESPTKHSTIIFAATKHHVDYIASMLR 402
                 5555.56666666666644444555555666666666666666666666666666666655555555589999*********************99998 PP

         SLS  86 ei 87 
                 e+
  EEA21462.1 403 EA 404
                 86 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.26
         SLS  92 ttetvdlsellkl....skvdklkdl.lseelleelgrltntvievs....eddnnknskselki 147
                 ttetvd+++  k+    ++ ++ +d+   +++l+ ++  +++ +ev+    +++n   +++  k 
  EEA21462.1 655 TTETVDANADEKDdvemDNGFSDEDDeTPKDNLDNMSMASESDLEVTfsqySQSN---KNKSKKG 716
                 5677775555555666655556666668888888888888888887764442222...2223333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (948 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       979  (0.0546043); expected 358.6 (0.02)
Passed bias filter:                      436  (0.0243181); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.75u 0.30s 00:00:01.05 Elapsed: 00:00:00.45
# Mc/sec: 6279.41
//
Query:       EEA21463.1  [L=271]
Description: isopentenyl-diphosphate delta-isomerase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-27   95.7   0.0    3.1e-27   95.2   0.0    1.3  1  NUDIX     NUDIX domain


Domain annotation for each model (and alignments):
>> NUDIX  NUDIX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.2   0.0   1.7e-31   3.1e-27       2     131 .]      92     239 ..      91     239 .. 0.94

  Alignments for each domain:
  == domain 1  score: 95.2 bits;  conditional E-value: 1.7e-31
                 EEEEEEEEEEETTSEEEEEEES..SSSTTT.E....E.SSEEECBT........TSHHHHHHHHHHHHHHSEEEEEE.....EEEEEEEEEEEEEEEEE CS
       NUDIX   2 lrravgvvllnekgevLlvrrs..kkpfpg.W....e.lPgGkvep........gEtpeeAArREleEEtGleaell.....ellgrlhylapydgpyg 79 
                 l+ra++v+l+++++++Ll++r+  k +fp+ W    + +P G   +         E ++ AA+R+l  E+G++ae++     ++l+r+hylap+dg++g
  EEA21463.1  92 LHRAFSVFLFDSQNRLLLQQRAaeKITFPDlWtntcCsHPLGIAGEtgaelsaaIEGVKRAAIRKLDQELGIKAEQVpldkfKFLTRIHYLAPSDGKWG 190
                 79*****************************9999747997777766667777788****************9999999999***************** PP

                 EEEEEEEEEEEEECSGCSSTSTTTEEEEEEEEHHHHHHHHTHCTHHHHHHHH CS
       NUDIX  80 deheilyvfleevegelepndenevsevrwvpleellkeklaaesrkllpwl 131
                  ehei+y+++ +++ ++ pn +nev++ ++v++eel k ++a+++ k++pw+
  EEA21463.1 191 -EHEIDYILFIQADVDVIPN-PNEVQDTKYVTPEEL-KSMFANPALKFTPWF 239
                 .9*****************9.***************.**************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (271 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       297  (0.0165653); expected 358.6 (0.02)
Passed bias filter:                      279  (0.0155614); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1857.41
//
Query:       EEA21464.1  [L=375]
Description: C2H2 finger domain protein (Ezf), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.2e-10   39.0  22.9     0.0028   18.0   3.9    3.7  3  zf-C2H2         Zinc finger, C2H2 type
      9e-10   38.5  18.3    6.1e-05   23.3   0.3    3.7  3  zf-H2C2_2       Zinc-finger double domain
    2.4e-09   37.2  17.4      0.017   15.9   2.7    3.8  3  zf-C2H2_4       C2H2-type zinc finger
    2.8e-06   27.5   8.3     0.0082   16.5   0.2    3.9  3  zf-met          Zinc-finger of C2H2 type
    2.3e-05   24.3   8.8        0.4   10.7   0.3    3.6  3  zf-C2H2_6       C2H2-type zinc finger
    3.1e-05   24.1   6.8       0.52   10.7   0.2    3.5  3  zf-C2H2_jaz     Zinc-finger double-stranded RNA-binding
  ------ inclusion threshold ------
      0.024   14.6  13.7        1.9    8.6   1.9    3.5  3  zf-BED          BED zinc finger
       0.03   14.4  10.6       0.33   11.1   0.6    3.0  2  Zn-ribbon_8     Zinc ribbon domain
       0.14   12.5   9.5       0.32   11.3   0.5    3.3  3  zf-C2H2_2       C2H2 type zinc-finger (2 copies)
       0.24   11.9   2.3        1.8    9.1   0.2    3.2  2  Zn-C2H2_12      Autophagy receptor zinc finger-C2H2 domain
       0.71   10.1  11.6        2.4    8.3  10.9    2.2  1  FYVE            FYVE zinc finger
       0.74   10.2   7.9       0.64   10.4   3.8    2.3  2  zf-Di19         Drought induced 19 protein (Di19), zinc-bindi
          3    8.6   9.2        4.4    8.0   0.4    2.8  3  zf-C2H2_3rep    Zinc finger C2H2-type, 3 repeats
        3.5    8.0   8.3         17    5.8   5.8    2.6  2  Rpr2            RNAse P Rpr2/Rpp21/SNM1 subunit domain
        4.8    7.3   7.8         24    5.0   0.1    2.9  3  Elf1            Transcription elongation factor Elf1 like
        7.6    6.6   6.9         28    4.8   1.3    2.5  2  zinc-ribbons_6  zinc-ribbons


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   3.9   2.5e-06    0.0028       2      23 .]     266     287 ..     265     287 .. 0.97
   2 !   17.8   2.9   2.9e-06    0.0032       1      23 []     295     319 ..     295     319 .. 0.91
   3 !   13.9   1.2     5e-05     0.056       1      21 [.     325     345 ..     325     346 .. 0.96

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 2.5e-06
                 EETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   2 kCpdCgksFkrksnLkrHirtH 23 
                 +Cp C+k+F+r+sn + H+++H
  EEA21464.1 266 RCPLCDKVFTRRSNCREHLKRH 287
                 8********************9 PP

  == domain 2  score: 17.8 bits;  conditional E-value: 2.9e-06
                 EEETTTTEEESSHHHHHHHHHC..C CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirt..H 23 
                 ++C  Cgk+F rk +LkrH++t  H
  EEA21464.1 295 HPCRSCGKTFGRKTDLKRHYMTriH 319
                 68*****************998666 PP

  == domain 3  score: 13.9 bits;  conditional E-value: 5e-05
                 EEETTTTEEESSHHHHHHHHH CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHir 21 
                 ++C+ Cg+ ++r + + rH++
  EEA21464.1 325 FTCDLCGRQYSRLDTMHRHQK 345
                 89*****************97 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.1   0.0   0.00039      0.44      15      26 .]     265     276 ..     259     276 .. 0.87
   2 !   14.5   3.3   3.3e-05     0.037       2      25 ..     280     305 ..     279     306 .. 0.90
   3 !   23.3   0.3   5.4e-08   6.1e-05       1      25 [.     309     335 ..     309     336 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00039
   zf-H2C2_2  15 yeCplCdkaFkt 26 
                 + CplCdk+F++
  EEA21464.1 265 LRCPLCDKVFTR 276
                 78********85 PP

  == domain 2  score: 14.5 bits;  conditional E-value: 3.3e-05
   zf-H2C2_2   2 LrrHirkHtgekp..yeCplCdkaFk 25 
                  r H++ H + ++  + C +C+k+F 
  EEA21464.1 280 CREHLKRHNPVNRqaHPCRSCGKTFG 305
                 589********9889**********7 PP

  == domain 3  score: 23.3 bits;  conditional E-value: 5.4e-08
   zf-H2C2_2   1 nLrrH..irkHtgekpyeCplCdkaFk 25 
                 +L+rH  +r H gek+++C+lC+  ++
  EEA21464.1 309 DLKRHymTRIHDGEKRFTCDLCGRQYS 335
                 69***76699************98876 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   2.7   1.5e-05     0.017       2      23 ..     266     287 ..     265     288 .. 0.94
   2 !   15.4   1.0   2.3e-05     0.025       1      21 [.     295     315 ..     295     317 .. 0.91
   3 !   14.8   0.6   3.5e-05     0.039       1      21 [.     325     345 ..     325     346 .. 0.95

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 1.5e-05
   zf-C2H2_4   2 kCpiCgksFsskkaLlrHlkth 23 
                 +Cp+C+k+F+++++ + Hlk+h
  EEA21464.1 266 RCPLCDKVFTRRSNCREHLKRH 287
                 7*********9999999****9 PP

  == domain 2  score: 15.4 bits;  conditional E-value: 2.3e-05
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlk 21 
                 ++C+ Cgk+F +k++L+rH  
  EEA21464.1 295 HPCRSCGKTFGRKTDLKRHYM 315
                 68*****************76 PP

  == domain 3  score: 14.8 bits;  conditional E-value: 3.5e-05
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlk 21 
                 f+C++Cg+ +s+ +++ rH k
  EEA21464.1 325 FTCDLCGRQYSRLDTMHRHQK 345
                 89*****************87 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.2   7.3e-06    0.0082       2      21 ..     266     285 ..     265     285 .. 0.94
   2 !    8.3   0.3    0.0029       3.2       3      25 .]     297     319 ..     295     319 .. 0.90
   3 ?    5.9   0.2     0.016        18       1      19 [.     325     343 ..     325     345 .. 0.87

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 7.3e-06
      zf-met   2 yCelCnvtfnsesqlksHlq 21 
                  C+lC+++f+ +s+ + Hl+
  EEA21464.1 266 RCPLCDKVFTRRSNCREHLK 285
                 6*****************96 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.0029
      zf-met   3 CelCnvtfnsesqlksHlqGKkH 25 
                 C  C +tf  +++lk H+  + H
  EEA21464.1 297 CRSCGKTFGRKTDLKRHYMTRIH 319
                 999**************977666 PP

  == domain 3  score: 5.9 bits;  conditional E-value: 0.016
      zf-met   1 fyCelCnvtfnsesqlksH 19 
                 f+C+lC ++++   ++  H
  EEA21464.1 325 FTCDLCGRQYSRLDTMHRH 343
                 89********998888888 PP

>> zf-C2H2_6  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.7   0.3   0.00036       0.4       3      24 ..     266     287 ..     266     290 .. 0.94
   2 !    8.8   0.2    0.0015       1.7       1      17 [.     294     310 ..     294     313 .. 0.80
   3 !    8.7   0.3    0.0015       1.7       2      17 ..     325     340 ..     324     345 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00036
   zf-C2H2_6   3 eCsvCsksFpslqaLggHkksH 24 
                 +C+ C+k+F    + ++H+k+H
  EEA21464.1 266 RCPLCDKVFTRRSNCREHLKRH 287
                 6*******************99 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0015
   zf-C2H2_6   1 vheCsvCsksFpslqaL 17 
                 +h C  C+k+F+  ++L
  EEA21464.1 294 AHPCRSCGKTFGRKTDL 310
                 69*********875555 PP

  == domain 3  score: 8.7 bits;  conditional E-value: 0.0015
   zf-C2H2_6   2 heCsvCsksFpslqaL 17 
                 + C+ C+++++ l+ +
  EEA21464.1 325 FTCDLCGRQYSRLDTM 340
                 99*********99865 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.7   0.2   0.00046      0.52       3      22 ..     266     285 ..     264     285 .. 0.89
   2 !    7.4   0.1    0.0048       5.4       4      26 ..     297     319 ..     294     319 .. 0.86
   3 !    8.3   0.1    0.0025       2.8       2      22 ..     325     345 ..     324     345 .. 0.93

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00046
                  BBTTTTBBBSSHHHHHCCTT CS
  zf-C2H2_jaz   3 YCvlCdKyFksenaldnHlk 22 
                   C+lCdK F   ++ ++Hlk
   EEA21464.1 266 RCPLCDKVFTRRSNCREHLK 285
                  7*********9999999987 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0048
                  BTTTTBBBSSHHHHHCCTTSHHH CS
  zf-C2H2_jaz   4 CvlCdKyFksenaldnHlkSKkH 26 
                  C  C K+F    +l+ H+ ++ H
   EEA21464.1 297 CRSCGKTFGRKTDLKRHYMTRIH 319
                  999**************966665 PP

  == domain 3  score: 8.3 bits;  conditional E-value: 0.0025
                  CBBTTTTBBBSSHHHHHCCTT CS
  zf-C2H2_jaz   2 fYCvlCdKyFksenaldnHlk 22 
                  f C lC ++++   ++  H+k
   EEA21464.1 325 FTCDLCGRQYSRLDTMHRHQK 345
                  99***********99999987 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.7    0.0049       5.5      18      41 ..     266     286 ..     263     296 .. 0.76
   2 ?    6.9   0.6    0.0059       6.6      14      38 ..     292     313 ..     288     319 .. 0.84
   3 ?    8.6   1.9    0.0017       1.9       6      38 ..     314     343 ..     313     349 .. 0.75

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0049
                 EETTTTEE----SSTHHHHHHHHH CS
      zf-BED  18 vCryCgkilsrgggttnLkrHLrr 41 
                 +C  C k+++r+   +n + HL+r
  EEA21464.1 266 RCPLCDKVFTRR---SNCREHLKR 286
                 7**********9...788888833 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0059
                 SS--EETTTTEE----SSTHHHHHH CS
      zf-BED  14 eqkavCryCgkilsrgggttnLkrH 38 
                 +q   Cr Cgk++ r+   t LkrH
  EEA21464.1 292 RQAHPCRSCGKTFGRK---TDLKRH 313
                 66777**********9...999999 PP

  == domain 3  score: 8.6 bits;  conditional E-value: 0.0017
                 SS----GGSS--EETTTTEE----SSTHHHHHH CS
      zf-BED   6 yftpvslkeqkavCryCgkilsrgggttnLkrH 38 
                 y t++   e++ +C  Cg+++sr      + rH
  EEA21464.1 314 YMTRIHDGEKRFTCDLCGRQYSRL---DTMHRH 343
                 667777799*************94...555555 PP

>> Zn-ribbon_8  Zinc ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   3.7     0.012        13       5      36 ..     264     304 ..     264     308 .. 0.68
   2 ?   11.1   0.6   0.00029      0.33       6      31 ..     325     350 ..     324     350 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.012
  Zn-ribbon_8   5 eYrCeeCghefe.......vlqsisdap.......lta.CPeCgsev 36 
                  e rC  C+++f+       +l      +       + + C +Cg++ 
   EEA21464.1 264 ELRCPLCDKVFTrrsncreHL------KrhnpvnrQAHpCRSCGKTF 304
                  679*********666666533......133334446677****9865 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00029
  Zn-ribbon_8   6 YrCeeCghefevlqsisdaplta.CPe 31 
                  + C+ Cg+++ +l ++++   ++ CPe
   EEA21464.1 325 FTCDLCGRQYSRLDTMHRHQ-KDgCPE 350
                  89**************9665.555**6 PP

>> zf-C2H2_2  C2H2 type zinc-finger (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.5   0.00029      0.32      44      74 ..     258     288 ..     255     295 .. 0.85
   2 ?    3.2   0.5       0.1   1.1e+02      50      75 ..     294     319 ..     287     323 .. 0.84
   3 ?    1.9   1.5      0.26   2.9e+02      49      72 ..     323     346 ..     310     359 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00029
   zf-C2H2_2  44 rekieekleClyCekefkslealreHmkkkg 74 
                 + +++ +l+C +C+k f+ ++++reH+k ++
  EEA21464.1 258 QAELDPELRCPLCDKVFTRRSNCREHLKRHN 288
                 5678889********************8764 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.1
   zf-C2H2_2  50 kleClyCekefkslealreHmkkkgH 75 
                  + C  C+k+f  + +l+ H  ++ H
  EEA21464.1 294 AHPCRSCGKTFGRKTDLKRHYMTRIH 319
                 567*******9999*****9888777 PP

  == domain 3  score: 1.9 bits;  conditional E-value: 0.26
   zf-C2H2_2  49 ekleClyCekefkslealreHmkk 72 
                 ++++C +C+++ + l++++ H k+
  EEA21464.1 323 KRFTCDLCGRQYSRLDTMHRHQKD 346
                 4789*******99******99765 PP

>> Zn-C2H2_12  Autophagy receptor zinc finger-C2H2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.2    0.0016       1.8       3      11 ..     267     275 ..     266     287 .. 0.83
   2 ?    0.6   0.0       0.7   7.9e+02       3      11 ..     327     335 ..     326     341 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0016
  Zn-C2H2_12   3 CPlCseqFp 11 
                 CPlC+++F 
  EEA21464.1 267 CPLCDKVFT 275
                 ********6 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.7
  Zn-C2H2_12   3 CPlCseqFp 11 
                 C lC+ q++
  EEA21464.1 327 CDLCGRQYS 335
                 889*****9 PP

>> FYVE  FYVE zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3  10.9    0.0022       2.4      11      67 ..     266     335 ..     260     336 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.0022
                 B-TTT--B--..............SSS--EE-TTT--EE-STTS-EEE.EEGGGTEEEEEEE-HHHHHHHH CS
        FYVE  11 kCeiCakkFs..............llrrrhhCrlCGkvvCekCssklvallekeaeeksvrvCkeClaels 67 
                 +C+ C+k F+              + r+ h Cr CGk + +k   k+  ++ + ++ ++  +C+ C +++s
  EEA21464.1 266 RCPLCDKVFTrrsncrehlkrhnpVNRQAHPCRSCGKTFGRKTDLKRHYMT-RIHDGEKRFTCDLCGRQYS 335
                 6999999998566665555555533455677*********99988888555.7788888889999988875 PP

>> zf-Di19  Drought induced 19 protein (Di19), zinc-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   3.8   0.00057      0.64       3      50 ..     265     315 ..     263     320 .. 0.79
   2 ?    0.6   0.1      0.63   7.1e+02       2      20 ..     324     343 ..     323     349 .. 0.65

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00057
     zf-Di19   3 ftCPyCgkeltvkeLv.eHvedeHrveskevvCPvCaekvtk..dlvaHlt 50 
                 + CP C k +t  + + eH++ + +v+++ + C  C ++ ++  dl +H +
  EEA21464.1 265 LRCPLCDKVFTRRSNCrEHLKRHNPVNRQAHPCRSCGKTFGRktDLKRHYM 315
                 68******877665553899999999**********999664348888865 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.63
     zf-Di19   2 sftCPyCgk.eltvkeLveH 20 
                  ftC  Cg+     +++ +H
  EEA21464.1 324 RFTCDLCGRqYSRLDTMHRH 343
                 68999999833445555555 PP

>> zf-C2H2_3rep  Zinc finger C2H2-type, 3 repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.1       8.2   9.2e+03      72      82 ..     199     209 ..     166     231 .. 0.51
   2 ?    5.5   0.8     0.023        26      94     122 ..     287     315 ..     269     319 .. 0.76
   3 ?    8.0   0.4     0.004       4.4      96     121 ..     319     344 ..     315     347 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 8.2
  zf-C2H2_3rep  72 sasedssqkle 82 
                    +     + le
    EEA21464.1 199 VSRRAHLESLE 209
                   22222222222 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.023
  zf-C2H2_3rep  94 enesgvrkfvcrfcGlkfdllpdlGrhhq 122
                   +n  + + + cr cG  f    dl rh+ 
    EEA21464.1 287 HNPVNRQAHPCRSCGKTFGRKTDLKRHYM 315
                   4555566788**************99975 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.004
  zf-C2H2_3rep  96 esgvrkfvcrfcGlkfdllpdlGrhh 121
                   ++g+++f+c +cG ++  l  + rh 
    EEA21464.1 319 HDGEKRFTCDLCGRQYSRLDTMHRHQ 344
                   5789****************999997 PP

>> Rpr2  RNAse P Rpr2/Rpp21/SNM1 subunit domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   5.8     0.015        17      47      89 ..     266     330 ..     244     331 .. 0.67
   2 ?    3.1   0.2      0.11   1.2e+02      32      65 ..     311     344 ..     302     367 .. 0.72

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.015
                 B-TTT--B--CTTTEEEEEE-SSS-E.................................EEEEETTT CS
        Rpr2  47 vCkkCgsvlipgvtcsvrvenkskkkkkkkkka........................dvlvvtClaC 89 
                  C  C++v++  ++c+ ++++++  +++ ++ +                        ++  +tC  C
  EEA21464.1 266 RCPLCDKVFTRRSNCREHLKRHNPVNRQAHPCRscgktfgrktdlkrhymtrihdgeKR--FTCDLC 330
                 4******************9866554444333366666666666666555555555444..666666 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.11
                 HHHCT---SSTCCCTB-TTT--B--CTTTEEEEE CS
        Rpr2  32 skkaqlrlppsvkrtvCkkCgsvlipgvtcsvrv 65 
                  +++ +r+++  kr +C  Cg  +    t++ ++
  EEA21464.1 311 KRHYMTRIHDGEKRFTCDLCGRQYSRLDTMHRHQ 344
                 566777999999********98776665555555 PP

>> Elf1  Transcription elongation factor Elf1 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       4.1   4.5e+03      18      38 ..      21      41 ..       6      45 .. 0.65
   2 ?    2.1   4.9      0.18     2e+02       3      55 ..     247     304 ..     245     313 .. 0.62
   3 ?    5.0   0.1     0.022        24       3      31 ..     306     334 ..     304     347 .. 0.74

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 4.1
        Elf1 18 lptkFdCpfCnheksvevkld 38
                    F+ p+  +++sv+vk +
  EEA21464.1 21 NMFDFNDPYMTSSDSVQVKAE 41
                445688888889999999876 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.18
        Elf1   3 RkkkakkrkkkkkkklptkFdCpfCnheks....vevkldkkek....iaevsCkvCgesf 55 
                 R++k+++r + ++ +l+ + +Cp C++  +    ++ +l++  +    +    C++Cg++f
  EEA21464.1 247 RREKSATRGQAQA-ELDPELRCPLCDKVFTrrsnCREHLKR--HnpvnRQAHPCRSCGKTF 304
                 5666665555544.4**********9875522113333333..244655555688888876 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.022
        Elf1   3 RkkkakkrkkkkkkklptkFdCpfCnhek 31 
                 Rk+  k++   + +  +++F+C  C+ + 
  EEA21464.1 306 RKTDLKRHYMTRIHDGEKRFTCDLCGRQY 334
                 66644445667788899********9874 PP

>> zinc-ribbons_6  zinc-ribbons
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.4     0.034        38      15      33 ..     263     281 ..     246     292 .. 0.74
   2 ?    4.8   1.3     0.025        28       3      29 ..     297     337 ..     290     350 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.034
                     SEEE-TTT--EEEEEEE-S CS
  zinc-ribbons_6  15 eqyhCeaCqedlkkealCp 33 
                      +++C  C++ +++   C 
      EEA21464.1 263 PELRCPLCDKVFTRRSNCR 281
                     4677888888888887775 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.025
                     -SSS-S--EE-S..............SEEE-TTT--EEEEE CS
  zinc-ribbons_6   3 CpeCqqelekrg..............eqyhCeaCqedlkke 29 
                     C++C +   +++              ++++C+ C +++++ 
      EEA21464.1 297 CRSCGKTFGRKTdlkrhymtrihdgeKRFTCDLCGRQYSRL 337
                     99999998866668888888888888999999999988764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (375 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       705  (0.0393218); expected 358.6 (0.02)
Passed bias filter:                      384  (0.0214178); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                        23  (0.00128284); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              16  [number of targets reported over threshold]
# CPU time: 0.53u 0.30s 00:00:00.83 Elapsed: 00:00:00.48
# Mc/sec: 2357.24
//
Query:       EEA21465.1  [L=269]
Description: C2H2 finger domain protein (Ezf), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.4e-10   41.1  17.7    3.9e-05   23.9   0.3    3.8  3  zf-H2C2_2       Zinc-finger double domain
    1.9e-10   40.6  22.9     0.0019   18.6   3.9    3.6  3  zf-C2H2         Zinc finger, C2H2 type
    6.7e-10   39.0  17.4      0.011   16.5   2.7    3.8  3  zf-C2H2_4       C2H2-type zinc finger
    2.5e-06   27.7   9.9     0.0054   17.1   0.2    3.9  3  zf-met          Zinc-finger of C2H2 type
    6.5e-06   26.0   8.9       0.26   11.3   0.3    3.6  3  zf-C2H2_6       C2H2-type zinc finger
    9.3e-06   25.8   6.8       0.34   11.2   0.2    3.5  3  zf-C2H2_jaz     Zinc-finger double-stranded RNA-binding
     0.0059   16.6  13.5        1.2    9.3   1.8    3.5  3  zf-BED          BED zinc finger
  ------ inclusion threshold ------
       0.01   15.9  10.5       0.21   11.7   0.6    3.0  2  Zn-ribbon_8     Zinc ribbon domain
      0.042   14.3   1.4        1.2    9.7   0.2    3.5  4  Zn-C2H2_12      Autophagy receptor zinc finger-C2H2 domain
      0.055   13.8   9.9       0.39   11.1   1.8    3.3  3  zf-C2H2_2       C2H2 type zinc-finger (2 copies)
       0.37   10.8   5.5        2.9    8.0   0.6    2.8  3  ADK_lid         Adenylate kinase, active site lid
       0.45   10.7  12.0        1.9    8.7  11.4    2.3  1  FYVE            FYVE zinc finger
       0.49   10.7   8.5       0.41   11.0   3.9    2.3  2  zf-Di19         Drought induced 19 protein (Di19), zinc-bindi
       0.56   10.9   8.3        2.9    8.6   0.4    2.8  3  zf-C2H2_3rep    Zinc finger C2H2-type, 3 repeats
       0.67    9.9   4.1        9.8    6.2   0.0    3.2  3  zinc_ribbon_4   zinc-ribbon domain
        1.5    9.2   8.3        8.9    6.7   5.6    2.5  2  Rpr2            RNAse P Rpr2/Rpp21/SNM1 subunit domain
        2.6    7.9   6.1         25    4.8   0.2    2.9  2  zf-H2C2_5       C2H2-type zinc-finger domain
        2.9    8.0   6.8    1.1e+02    2.9   3.0    2.5  2  zinc-ribbons_6  zinc-ribbons
        5.5    7.1   8.6         17    5.6   0.2    2.6  2  Elf1            Transcription elongation factor Elf1 like
        8.4    6.4   8.2         37    4.3   0.1    3.3  3  zf-LYAR         LYAR-type C2HC zinc finger
        9.6    6.3   8.9    2.8e+02    1.6   8.8    2.7  2  DZR             Double zinc ribbon


Domain annotation for each model (and alignments):
>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.6   0.0   0.00034      0.29      15      26 .]     159     170 ..     152     170 .. 0.87
   2 !   15.1   3.3   2.8e-05     0.024       2      25 ..     174     199 ..     173     200 .. 0.90
   3 !   23.9   0.3   4.6e-08   3.9e-05       1      25 [.     203     229 ..     203     230 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00034
   zf-H2C2_2  15 yeCplCdkaFkt 26 
                 + CplCdk+F++
  EEA21465.1 159 LRCPLCDKVFTR 170
                 78********85 PP

  == domain 2  score: 15.1 bits;  conditional E-value: 2.8e-05
   zf-H2C2_2   2 LrrHirkHtgekp..yeCplCdkaFk 25 
                  r H++ H + ++  + C +C+k+F 
  EEA21465.1 174 CREHLKRHNPVNRqaHPCRSCGKTFG 199
                 589********9889**********7 PP

  == domain 3  score: 23.9 bits;  conditional E-value: 4.6e-08
   zf-H2C2_2   1 nLrrH..irkHtgekpyeCplCdkaFk 25 
                 +L+rH  +r H gek+++C+lC+  ++
  EEA21465.1 203 DLKRHymTRIHDGEKRFTCDLCGRQYS 229
                 69***76699************98876 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   3.9   2.2e-06    0.0019       2      23 .]     160     181 ..     159     181 .. 0.97
   2 !   18.4   2.9   2.5e-06    0.0021       1      23 []     189     213 ..     189     213 .. 0.91
   3 !   14.5   1.2   4.3e-05     0.037       1      21 [.     219     239 ..     219     240 .. 0.96

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 2.2e-06
                 EETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   2 kCpdCgksFkrksnLkrHirtH 23 
                 +Cp C+k+F+r+sn + H+++H
  EEA21465.1 160 RCPLCDKVFTRRSNCREHLKRH 181
                 8********************9 PP

  == domain 2  score: 18.4 bits;  conditional E-value: 2.5e-06
                 EEETTTTEEESSHHHHHHHHHC..C CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirt..H 23 
                 ++C  Cgk+F rk +LkrH++t  H
  EEA21465.1 189 HPCRSCGKTFGRKTDLKRHYMTriH 213
                 68*****************998666 PP

  == domain 3  score: 14.5 bits;  conditional E-value: 4.3e-05
                 EEETTTTEEESSHHHHHHHHH CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHir 21 
                 ++C+ Cg+ ++r + + rH++
  EEA21465.1 219 FTCDLCGRQYSRLDTMHRHQK 239
                 89*****************97 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   2.7   1.3e-05     0.011       2      23 ..     160     181 ..     159     182 .. 0.94
   2 !   16.0   1.0   1.9e-05     0.016       1      21 [.     189     209 ..     189     211 .. 0.91
   3 !   15.4   0.6     3e-05     0.026       1      21 [.     219     239 ..     219     240 .. 0.95

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 1.3e-05
   zf-C2H2_4   2 kCpiCgksFsskkaLlrHlkth 23 
                 +Cp+C+k+F+++++ + Hlk+h
  EEA21465.1 160 RCPLCDKVFTRRSNCREHLKRH 181
                 7*********9999999****9 PP

  == domain 2  score: 16.0 bits;  conditional E-value: 1.9e-05
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlk 21 
                 ++C+ Cgk+F +k++L+rH  
  EEA21465.1 189 HPCRSCGKTFGRKTDLKRHYM 209
                 68*****************76 PP

  == domain 3  score: 15.4 bits;  conditional E-value: 3e-05
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlk 21 
                 f+C++Cg+ +s+ +++ rH k
  EEA21465.1 219 FTCDLCGRQYSRLDTMHRHQK 239
                 89*****************87 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   0.2   6.4e-06    0.0054       2      21 ..     160     179 ..     159     179 .. 0.94
   2 !    8.8   0.3    0.0025       2.1       3      25 .]     191     213 ..     189     213 .. 0.90
   3 ?    6.5   0.2     0.014        12       1      19 [.     219     237 ..     219     239 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 6.4e-06
      zf-met   2 yCelCnvtfnsesqlksHlq 21 
                  C+lC+++f+ +s+ + Hl+
  EEA21465.1 160 RCPLCDKVFTRRSNCREHLK 179
                 6*****************96 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0025
      zf-met   3 CelCnvtfnsesqlksHlqGKkH 25 
                 C  C +tf  +++lk H+  + H
  EEA21465.1 191 CRSCGKTFGRKTDLKRHYMTRIH 213
                 999**************977666 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.014
      zf-met   1 fyCelCnvtfnsesqlksH 19 
                 f+C+lC ++++   ++  H
  EEA21465.1 219 FTCDLCGRQYSRLDTMHRH 237
                 89********998888888 PP

>> zf-C2H2_6  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.3   0.3   0.00031      0.26       3      24 ..     160     181 ..     160     184 .. 0.94
   2 !    9.3   0.2    0.0013       1.1       1      17 [.     188     204 ..     188     207 .. 0.80
   3 !    9.3   0.3    0.0013       1.1       2      17 ..     219     234 ..     218     239 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00031
   zf-C2H2_6   3 eCsvCsksFpslqaLggHkksH 24 
                 +C+ C+k+F    + ++H+k+H
  EEA21465.1 160 RCPLCDKVFTRRSNCREHLKRH 181
                 6*******************99 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.0013
   zf-C2H2_6   1 vheCsvCsksFpslqaL 17 
                 +h C  C+k+F+  ++L
  EEA21465.1 188 AHPCRSCGKTFGRKTDL 204
                 69*********976555 PP

  == domain 3  score: 9.3 bits;  conditional E-value: 0.0013
   zf-C2H2_6   2 heCsvCsksFpslqaL 17 
                 + C+ C+++++ l+ +
  EEA21465.1 219 FTCDLCGRQYSRLDTM 234
                 99*********99865 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.2    0.0004      0.34       3      22 ..     160     179 ..     158     179 .. 0.89
   2 !    8.0   0.1    0.0041       3.5       4      26 ..     191     213 ..     188     213 .. 0.86
   3 !    8.9   0.1    0.0022       1.9       2      22 ..     219     239 ..     218     239 .. 0.93

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.0004
                  BBTTTTBBBSSHHHHHCCTT CS
  zf-C2H2_jaz   3 YCvlCdKyFksenaldnHlk 22 
                   C+lCdK F   ++ ++Hlk
   EEA21465.1 160 RCPLCDKVFTRRSNCREHLK 179
                  7*********9999999987 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0041
                  BTTTTBBBSSHHHHHCCTTSHHH CS
  zf-C2H2_jaz   4 CvlCdKyFksenaldnHlkSKkH 26 
                  C  C K+F    +l+ H+ ++ H
   EEA21465.1 191 CRSCGKTFGRKTDLKRHYMTRIH 213
                  999**************966665 PP

  == domain 3  score: 8.9 bits;  conditional E-value: 0.0022
                  CBBTTTTBBBSSHHHHHCCTT CS
  zf-C2H2_jaz   2 fYCvlCdKyFksenaldnHlk 22 
                  f C lC ++++   ++  H+k
   EEA21465.1 219 FTCDLCGRQYSRLDTMHRHQK 239
                  99************9999987 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.7   0.7    0.0041       3.5      18      41 ..     160     180 ..     157     190 .. 0.76
   2 !    7.0   1.2     0.007         6      14      38 ..     186     207 ..     181     213 .. 0.84
   3 !    9.3   1.8    0.0014       1.2       6      38 ..     208     237 ..     207     243 .. 0.75

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0041
                 EETTTTEE----SSTHHHHHHHHH CS
      zf-BED  18 vCryCgkilsrgggttnLkrHLrr 41 
                 +C  C k+++r+   +n + HL+r
  EEA21465.1 160 RCPLCDKVFTRR---SNCREHLKR 180
                 7**********9...788888833 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.007
                 SS--EETTTTEE----SSTHHHHHH CS
      zf-BED  14 eqkavCryCgkilsrgggttnLkrH 38 
                 +q   Cr Cgk++ r+   t LkrH
  EEA21465.1 186 RQAHPCRSCGKTFGRK---TDLKRH 207
                 67778**********9...999999 PP

  == domain 3  score: 9.3 bits;  conditional E-value: 0.0014
                 SS----GGSS--EETTTTEE----SSTHHHHHH CS
      zf-BED   6 yftpvslkeqkavCryCgkilsrgggttnLkrH 38 
                 y t++   e++ +C  Cg+++sr      + rH
  EEA21465.1 208 YMTRIHDGEKRFTCDLCGRQYSRL---DTMHRH 237
                 667777799*************94...555555 PP

>> Zn-ribbon_8  Zinc ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   3.6    0.0091       7.8       5      36 ..     158     198 ..     158     202 .. 0.68
   2 ?   11.7   0.6   0.00025      0.21       6      31 ..     219     244 ..     218     244 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0091
  Zn-ribbon_8   5 eYrCeeCghefe.......vlqsisdap.......lta.CPeCgsev 36 
                  e rC  C+++f+       +l      +       + + C +Cg++ 
   EEA21465.1 158 ELRCPLCDKVFTrrsncreHL------KrhnpvnrQAHpCRSCGKTF 198
                  679*********666666533......133334446777****9865 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 0.00025
  Zn-ribbon_8   6 YrCeeCghefevlqsisdaplta.CPe 31 
                  + C+ Cg+++ +l ++++   ++ CPe
   EEA21465.1 219 FTCDLCGRQYSRLDTMHRHQ-KDgCPE 244
                  89**************9665.555**6 PP

>> Zn-C2H2_12  Autophagy receptor zinc finger-C2H2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       9.5   8.1e+03       8      17 ..      21      30 ..      20      31 .. 0.84
   2 ?    9.7   0.2    0.0014       1.2       3      11 ..     161     169 ..     160     181 .. 0.83
   3 ?   -2.4   0.0       8.3   7.1e+03       6      12 ..     194     200 ..     194     204 .. 0.77
   4 ?    1.3   0.0      0.56   4.8e+02       3      12 ..     221     230 ..     220     237 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 9.5
  Zn-C2H2_12  8 eqFpknvdqd 17
                 ++++++d++
  EEA21465.1 21 LYYQSGYDVN 30
                589****997 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.0014
  Zn-C2H2_12   3 CPlCseqFp 11 
                 CPlC+++F 
  EEA21465.1 161 CPLCDKVFT 169
                 ********6 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 8.3
  Zn-C2H2_12   6 CseqFpk 12 
                 C+++F  
  EEA21465.1 194 CGKTFGR 200
                 ****965 PP

  == domain 4  score: 1.3 bits;  conditional E-value: 0.56
  Zn-C2H2_12   3 CPlCseqFpk 12 
                 C lC+ q++ 
  EEA21465.1 221 CDLCGRQYSR 230
                 889*****95 PP

>> zf-C2H2_2  C2H2 type zinc-finger (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   1.8   0.00046      0.39      44      74 ..     152     182 ..     149     198 .. 0.83
   2 ?    3.9   0.2      0.08        68      50      75 ..     188     213 ..     183     217 .. 0.84
   3 ?    2.7   1.0      0.18   1.6e+02      49      72 ..     217     240 ..     209     254 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00046
   zf-C2H2_2  44 rekieekleClyCekefkslealreHmkkkg 74 
                 + +++ +l+C +C+k f+ ++++reH+k ++
  EEA21465.1 152 QAELDPELRCPLCDKVFTRRSNCREHLKRHN 182
                 5678889********************8654 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.08
   zf-C2H2_2  50 kleClyCekefkslealreHmkkkgH 75 
                  + C  C+k+f  + +l+ H  ++ H
  EEA21465.1 188 AHPCRSCGKTFGRKTDLKRHYMTRIH 213
                 467*******9999*****9888777 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.18
   zf-C2H2_2  49 ekleClyCekefkslealreHmkk 72 
                 ++++C +C+++ + l++++ H k+
  EEA21465.1 217 KRFTCDLCGRQYSRLDTMHRHQKD 240
                 4689*******99******99765 PP

>> ADK_lid  Adenylate kinase, active site lid
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.4      0.05        43       4      31 ..     161     198 ..     159     203 .. 0.67
   2 ?    2.1   0.1      0.22   1.9e+02       4      12 ..     191     199 ..     189     208 .. 0.82
   3 ?    8.0   0.6    0.0033       2.9       1      13 [.     218     230 ..     218     251 .. 0.77

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.05
                 -TTT--EE........ETTT.B-.-SSTTB-TTT--.- CS
     ADK_lid   4 CpkCGrsY........hvvf.np.PkveglCDkCGepL 31 
                 Cp C +++        h++  np  ++   C  CG ++
  EEA21465.1 161 CPLCDKVFtrrsncreHLKRhNPvNRQAHPCRSCGKTF 198
                 88888888777766666555566336777888888765 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.22
                 -TTT--EEE CS
     ADK_lid   4 CpkCGrsYh 12 
                 C++CG+++ 
  EEA21465.1 191 CRSCGKTFG 199
                 999**9996 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.0033
                 EEE-TTT--EEET CS
     ADK_lid   1 RrvCpkCGrsYhv 13 
                 R +C  CGr Y++
  EEA21465.1 218 RFTCDLCGRQYSR 230
                 99*********83 PP

>> FYVE  FYVE zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7  11.4    0.0022       1.9      11      67 ..     160     229 ..     154     230 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0022
                 B-TTT--B--..............SSS--EE-TTT--EE-STTS-EEE.EEGGGTEEEEEEE-HHHHHHHH CS
        FYVE  11 kCeiCakkFs..............llrrrhhCrlCGkvvCekCssklvallekeaeeksvrvCkeClaels 67 
                 +C+ C+k F+              + r+ h Cr CGk + +k   k+  ++ + ++ ++  +C+ C +++s
  EEA21465.1 160 RCPLCDKVFTrrsncrehlkrhnpVNRQAHPCRSCGKTFGRKTDLKRHYMT-RIHDGEKRFTCDLCGRQYS 229
                 6999999998566665555555533455677*********99988888555.7788888889999988875 PP

>> zf-Di19  Drought induced 19 protein (Di19), zinc-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   3.9   0.00049      0.41       3      50 ..     159     209 ..     157     214 .. 0.79
   2 ?    1.1   0.2      0.57   4.8e+02       2      20 ..     218     237 ..     217     243 .. 0.65

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00049
     zf-Di19   3 ftCPyCgkeltvkeLv.eHvedeHrveskevvCPvCaekvtk..dlvaHlt 50 
                 + CP C k +t  + + eH++ + +v+++ + C  C ++ ++  dl +H +
  EEA21465.1 159 LRCPLCDKVFTRRSNCrEHLKRHNPVNRQAHPCRSCGKTFGRktDLKRHYM 209
                 68******877665553899999999**********999664448888865 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.57
     zf-Di19   2 sftCPyCgk.eltvkeLveH 20 
                  ftC  Cg+     +++ +H
  EEA21465.1 218 RFTCDLCGRqYSRLDTMHRH 237
                 68999999833445555555 PP

>> zf-C2H2_3rep  Zinc finger C2H2-type, 3 repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       5.9   5.1e+03      65      84 ..      86     105 ..      58     125 .. 0.50
   2 ?    6.2   0.8     0.018        15      93     122 ..     180     209 ..     161     214 .. 0.73
   3 ?    8.6   0.4    0.0034       2.9      96     121 ..     213     238 ..     209     241 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 5.9
  zf-C2H2_3rep  65 vaqkknlsasedssqklels 84 
                   ++++ n+ +     + le s
    EEA21465.1  86 IDKNVNSVSRRAHLESLERS 105
                   44333333333333333333 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.018
  zf-C2H2_3rep  93 senesgvrkfvcrfcGlkfdllpdlGrhhq 122
                    +n  + + + cr cG  f    dl rh+ 
    EEA21465.1 180 RHNPVNRQAHPCRSCGKTFGRKTDLKRHYM 209
                   344555566789999999999999999975 PP

  == domain 3  score: 8.6 bits;  conditional E-value: 0.0034
  zf-C2H2_3rep  96 esgvrkfvcrfcGlkfdllpdlGrhh 121
                   ++g+++f+c +cG ++  l  + rh 
    EEA21465.1 213 HDGEKRFTCDLCGRQYSRLDTMHRHQ 238
                   5789*****************99997 PP

>> zinc_ribbon_4  zinc-ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   0.0     0.012       9.8      26      36 .]     159     169 ..     156     169 .. 0.84
   2 ?    1.4   0.3      0.36   3.1e+02      28      35 ..     191     198 ..     185     199 .. 0.78
   3 ?    1.7   0.1      0.29   2.4e+02       2      12 ..     218     228 ..     210     229 .. 0.57

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.012
  zinc_ribbon_4  26 vrCskCghvFr 36 
                    +rC+ C +vF+
     EEA21465.1 159 LRCPLCDKVFT 169
                    79999999996 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.36
  zinc_ribbon_4  28 CskCghvF 35 
                    C  Cg++F
     EEA21465.1 191 CRSCGKTF 198
                    77777776 PP

  == domain 3  score: 1.7 bits;  conditional E-value: 0.29
  zinc_ribbon_4   2 kitCpsCkaky 12 
                    ++tC  C+ +y
     EEA21465.1 218 RFTCDLCGRQY 228
                    34555555555 PP

>> Rpr2  RNAse P Rpr2/Rpp21/SNM1 subunit domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   5.6      0.01       8.9      47      89 ..     160     224 ..     139     225 .. 0.67
   2 ?    3.7   0.2     0.086        74      32      66 ..     205     239 ..     196     261 .. 0.72

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.01
                 B-TTT--B--CTTTEEEEEE-SSS-E.................................EEEEETTT CS
        Rpr2  47 vCkkCgsvlipgvtcsvrvenkskkkkkkkkka........................dvlvvtClaC 89 
                  C  C++v++  ++c+ ++++++  +++ ++ +                        ++  +tC  C
  EEA21465.1 160 RCPLCDKVFTRRSNCREHLKRHNPVNRQAHPCRscgktfgrktdlkrhymtrihdgeKR--FTCDLC 224
                 4******************9866554444443366666666666666666555555444..666666 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.086
                 HHHCT---SSTCCCTB-TTT--B--CTTTEEEEEE CS
        Rpr2  32 skkaqlrlppsvkrtvCkkCgsvlipgvtcsvrve 66 
                  +++ +r+++  kr +C  Cg  +    t++ +++
  EEA21465.1 205 KRHYMTRIHDGEKRFTCDLCGRQYSRLDTMHRHQK 239
                 566777999999********988766666555554 PP

>> zf-H2C2_5  C2H2-type zinc-finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   1.4     0.032        28       2      25 ..     160     182 ..     159     183 .. 0.89
   2 ?    4.8   0.2     0.029        25      12      26 .]     200     215 ..     199     215 .. 0.87

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.032
   zf-H2C2_5   2 KCsqCDYstawksnLkRHlrrkHt 25 
                 +C+ CD + +++sn ++Hl+  H+
  EEA21465.1 160 RCPLCDKVFTRRSNCREHLK-RHN 182
                 8999999999**********.887 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.029
   zf-H2C2_5  12 wksnLkRH.lrrkHtg 26 
                 +k +LkRH + r+H+g
  EEA21465.1 200 RKTDLKRHyMTRIHDG 215
                 699*****99999987 PP

>> zinc-ribbons_6  zinc-ribbons
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   3.0      0.13   1.1e+02      15      34 ..     157     176 ..     139     196 .. 0.70
   2 ?    1.0   6.7      0.52   4.4e+02       3      27 ..     191     229 ..     159     244 .. 0.62

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.13
                     SEEE-TTT--EEEEEEE-SS CS
  zinc-ribbons_6  15 eqyhCeaCqedlkkealCpe 34 
                      +++C  C++ +++   C e
      EEA21465.1 157 PELRCPLCDKVFTRRSNCRE 176
                     46678888888888777654 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.52
                     -SSS-S--EE-S..............SEEE-TTT--EEE CS
  zinc-ribbons_6   3 CpeCqqelekrg..............eqyhCeaCqedlk 27 
                     C++C +   +++              ++++C+ C ++++
      EEA21465.1 191 CRSCGKTFGRKTdlkrhymtrihdgeKRFTCDLCGRQYS 229
                     555555555444455555666666656666666666554 PP

>> Elf1  Transcription elongation factor Elf1 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   4.9      0.13   1.1e+02       3      55 ..     141     198 ..     139     208 .. 0.63
   2 ?    5.6   0.2     0.019        17       3      31 ..     200     228 ..     199     241 .. 0.73

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.13
        Elf1   3 RkkkakkrkkkkkkklptkFdCpfCnheks....vevkldkkek....iaevsCkvCgesf 55 
                 R++k+++r + ++ +l+ + +Cp C++  +    ++ +l++  +    +    C++Cg++f
  EEA21465.1 141 RREKSATRGQAQA-ELDPELRCPLCDKVFTrrsnCREHLKR--HnpvnRQAHPCRSCGKTF 198
                 5666665555544.4**********9875522113333443..244655555699998876 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.019
        Elf1   3 RkkkakkrkkkkkkklptkFdCpfCnhek 31 
                 Rk+  k++   + +  +++F+C  C+ + 
  EEA21465.1 200 RKTDLKRHYMTRIHDGEKRFTCDLCGRQY 228
                 56644445667788899********9874 PP

>> zf-LYAR  LYAR-type C2HC zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.1      0.22   1.8e+02       3      18 ..     161     177 ..     159     179 .. 0.82
   2 ?    4.3   0.1     0.044        37       3      18 ..     191     207 ..     190     208 .. 0.85
   3 ?    3.3   0.6      0.09        77       1      20 [.     219     239 ..     219     239 .. 0.92

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.22
     zf-LYAR   3 CiDCsktFdg.deykaH 18 
                 C  C k+F++  + ++H
  EEA21465.1 161 CPLCDKVFTRrSNCREH 177
                 667******98888888 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.044
     zf-LYAR   3 CiDCsktFdg.deykaH 18 
                 C  C+ktF + ++ k H
  EEA21465.1 191 CRSCGKTFGRkTDLKRH 207
                 666*****998889888 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.09
     zf-LYAR   1 fsCiDCsktFdg.deykaHts 20 
                 f+C  C+ ++++ d+   H +
  EEA21465.1 219 FTCDLCGRQYSRlDTMHRHQK 239
                 89**********9*9999975 PP

>> DZR  Double zinc ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.4      0.34   2.9e+02      27      41 ..     154     171 ..     140     177 .. 0.70
   2 ?    1.6   8.8      0.33   2.8e+02       7      39 ..     177     229 ..     161     244 .. 0.75

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.34
         DZR  27 a...edrCpsCgekvdpe 41 
                 +   e rCp C++  + +
  EEA21465.1 154 EldpELRCPLCDKVFTRR 171
                 144478999999876655 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.33
         DZR   7 e......lppdarfCseCgtklkavaa..............edrCpsCgekvd 39 
                        ++ +a+ C  Cg++  + ++                +C+ Cg++ +
  EEA21465.1 177 HlkrhnpVNRQAHPCRSCGKTFGRKTDlkrhymtrihdgekRFTCDLCGRQYS 229
                 35555458899999999999976555577888899999998889999999854 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (269 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       637  (0.035529); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                        27  (0.00150594); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              21  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.52
# Mc/sec: 1543.45
//
Query:       EEA21466.1  [L=1624]
Description: protein kinase (VPS15), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-24   87.2   0.0    1.8e-24   86.5   0.0    1.3  1  Pkinase       Protein kinase domain
    1.1e-12   47.1   5.1     0.0077   16.4   0.1    7.0  6  HEAT          HEAT repeat
    4.5e-08   33.6   7.5    1.5e-05   25.7   0.1    4.7  3  WD40          WD domain, G-beta repeat
    1.4e-06   27.9   0.0    3.5e-06   26.5   0.0    1.7  2  Pkinase_Tyr   Protein tyrosine kinase
    8.9e-05   22.6   0.3      0.027   14.5   0.0    3.3  3  Cnd1          non-SMC mitotic condensation complex subunit 1
    0.00013   22.3   0.0        3.7    8.0   0.0    4.0  3  HEAT_2        HEAT repeats
    0.00021   21.7   1.0        0.2   12.2   0.2    4.1  4  HEAT_EZ       HEAT-like repeat
  ------ inclusion threshold ------
       0.01   14.8   0.1      0.084   11.8   0.0    2.3  3  Ge1_WD40      WD40 region of Ge1, enhancer of mRNA-decapping 
      0.017   14.7   0.0      0.044   13.3   0.0    1.7  1  Tti2          Tti2 family
       0.05   13.8   0.3         16    5.7   0.0    2.7  2  RTP1_C1       Required for nuclear transport of RNA pol II C-
      0.051   13.9   2.1        8.9    6.7   0.1    3.1  2  Cohesin_HEAT  HEAT repeat associated with sister chromatid co
        5.8    5.5   9.2        9.5    4.8   9.2    1.2  1  MAP65_ASE1    Microtubule associated protein (MAP65/ASE1 fami


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.5   0.0   1.2e-27   1.8e-24       6     260 ..      30     286 ..      25     292 .. 0.80

  Alignments for each domain:
  == domain 1  score: 86.5 bits;  conditional E-value: 1.2e-27
                 EEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHH...HHHHHHHHHHHHHSCTTB--EEEEEEESSEEEEEEE--TTEBHHHHHHHHSS--HHHHH CS
     Pkinase   6 klGeGsfGkVykaveketgkivAvKkikkekakkkke...kkvlrEikilkklkhpnivrlyevfeekdelylvleyveggeladllerkgslseeeak 101
                  lG+  f k ++a+  +++    vK+i k   + + +   k+++rE ++l++   pn + + +++e+ ++ ylv +y++  +l d+l+++  l++ e k
  EEA21466.1  30 SLGSARFMKSIRAR--QRNGLAFVKVIMKPYPSMQLDhyvKEITRERELLAS--VPNALAYQRIIETGTSGYLVRQYIH-SSLYDRLSTRPFLEDIEKK 123
                 56666666655555..566667788888887776655445555555555554..69***********************.669****99999******* PP

                 HHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCS.........BCTTTSCGGGS-HHHH.......TTSCBSHHHHHHHHH CS
     Pkinase 102 kiakqilegleylHskgiiHrDlKpeNiLidekgelKitDFGlakelesssk.........ltsfvgtseYlAPEvl.......keneyskkvDvWslG 184
                  ia q+l +l+ +H+++++H D+K+eN+L+ + + l ++DF  + + +   +         +++      YlAPE         +++++  ++D++s+G
  EEA21466.1 124 WIAFQLLCALRDCHAQEVFHGDIKTENVLVTSWNWLYLSDFSSSFKPTFLPEdnpadfsfyFDTSGRRTCYLAPERFleageepGDRQVNWAMDIFSAG 222
                 *******************************9999*******9976554444556999997666667778*****99999888778999********** PP

                 HHHHHHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCTSHH...HHHTTS.-HHHHHHHHHHT-SSGCCSTTHHHHHT CS
     Pkinase 185 vilyelltgkppfsgekgkekvekeldqlekilkilgetkeklpeasei.seeakdllkkllkkdpkkRltaeellq 260
                 ++++el+ + p+f     ++    ++++        ge++ +  + s+i ++++++l+  +++ dp++R++aee l+
  EEA21466.1 223 CVIAELFLEAPIFT---LSQ--LYKYRK--------GEYSPEHSQLSKIeDSDVRELILHMIQIDPESRYSAEEYLN 286
                 **************...222..122222........23444444555556899********************9886 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.1   5.1e-06    0.0077       1      29 [.     434     462 ..     434     464 .. 0.95
   2 !   10.9   0.0   0.00031      0.46       9      29 ..     491     511 ..     483     513 .. 0.84
   3 !    6.6   0.0    0.0075        11       8      28 ..     569     589 ..     566     592 .. 0.87
   4 ?    2.2   0.0       0.2   2.9e+02       1      28 [.     601     628 ..     601     631 .. 0.84
   5 ?    4.5   0.0     0.034        51       1      28 [.     640     667 ..     640     669 .. 0.92
   6 ?    1.9   0.0      0.25   3.7e+02       1      29 [.     680     708 ..     680     710 .. 0.85

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 5.1e-06
                 HHHHHHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgalae 29 
                 +lP ++++l+D s  V  aA+++L++l++
  EEA21466.1 434 ILPYVMTMLNDRSDVVKVAAIRTLAQLLS 462
                 89*************************87 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00031
                 HT-SSHHHHHHHHHHHHHHHH CS
        HEAT   9 lsDpspeVReaAakaLgalae 29 
                   Dpsp VR+a a ++  la+
  EEA21466.1 491 SFDPSPMVRAAYASCISSLAQ 511
                 56*****************98 PP

  == domain 3  score: 6.6 bits;  conditional E-value: 0.0075
                 HHT-SSHHHHHHHHHHHHHHH CS
        HEAT   8 llsDpspeVReaAakaLgala 28 
                 ll+D++p+VR+a + ++  l+
  EEA21466.1 569 LLTDSDPSVRRAFLGSVSSLC 589
                 68**********999988887 PP

  == domain 4  score: 2.2 bits;  conditional E-value: 0.2
                 HHHHHHHHHT-SSHHHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgala 28 
                 +l +l + l+D+++   +a ++a++ +a
  EEA21466.1 601 ILSHLNTYLNDKDWILKCAFFEAVVGVA 628
                 68888999******99999999987766 PP

  == domain 5  score: 4.5 bits;  conditional E-value: 0.034
                 HHHHHHHHHT-SSHHHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgala 28 
                 +lPl++  l+D++ +V e ++++++ +a
  EEA21466.1 640 ILPLMVPSLTDTEDFVVERVIRSMASMA 667
                 89******************99999887 PP

  == domain 6  score: 1.9 bits;  conditional E-value: 0.25
                 HHHHHHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgalae 29 
                 ll+++++   +ps  +Rea+++ +++ ++
  EEA21466.1 680 LLNIVVRFFAHPSIWIREASVYFVVTCSK 708
                 7889999999**********998877666 PP

>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.7   0.1   9.9e-09   1.5e-05       7      38 .]    1137    1169 ..    1131    1169 .. 0.90
   2 ?    1.0   0.0      0.63   9.5e+02      10      35 ..    1187    1215 ..    1179    1215 .. 0.66
   3 !    7.8   0.0    0.0044       6.6      25      38 .]    1490    1502 ..    1460    1502 .. 0.78

  Alignments for each domain:
  == domain 1  score: 25.7 bits;  conditional E-value: 9.9e-09
                  EESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40    7 ltGH.ssvtslafspdgawlasGsdDgtvriWd 38  
                  +  H ++++ + + pd+a+++++sdDgtv++Wd
  EEA21466.1 1137 FGEHtGPINRVVVAPDHAFFVTASDDGTVKVWD 1169
                  7789888*************************9 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.63
                  SSS...EEEEEEETTSSEEEEEETTSEEE CS
        WD40   10 Hss...vtslafspdgawlasGsdDgtvr 35  
                  H +   v +l f  +   ++s+  Dg+++
  EEA21466.1 1187 HAPgtkVKCLTFVENTYTFVSAATDGSIH 1215
                  423456999986666666677766**995 PP

  == domain 3  score: 7.8 bits;  conditional E-value: 0.0044
                  EEEEETTSEEEEEE CS
        WD40   25 lasGsdDgtvriWd 38  
                  +++Gs D++vr+Wd
  EEA21466.1 1490 ISAGS-DRKVRFWD 1502
                  56788.*******9 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.5   0.0   2.4e-09   3.5e-06       3     254 ..      27     283 ..      25     287 .. 0.77
   2 ?   -3.2   0.0       2.7     4e+03      28      64 ..     970    1007 ..     961    1018 .. 0.77

  Alignments for each domain:
  == domain 1  score: 26.5 bits;  conditional E-value: 2.4e-09
                  EEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHTCTTTS CS
  Pkinase_Tyr   3 lgkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkklkhpnivkllgvctkeepllivteyvkgGdLlkfLrkkekekl 100
                  ++k+lG+ +f k ++++ +  +  + vkV++K   + + ++  +e+++e +++ +   pn +++  ++  + + ++v +y++  +L + L ++  + l
   EEA21466.1  27 YEKSLGSARFMKSIRARQR--NGLAFVKVIMKPYPSMQLDHYVKEITRERELLAS--VPNALAYQRIIETGTSGYLVRQYIH-SSLYDRLSTR--PFL 117
                  5788999999999988888..7777888888888777777778888888888876..5899999999999999*******96.69******98..999 PP

                  BHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEETTEEEE-STTTHEET..TTSSEE....EETTSSTSGGGGS-HHHHHHSE.......EEHH CS
  Pkinase_Tyr 101 tlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsenkvvkisDfGLardi..ekddey....vkkeeaklpvkWmapEslkekk.......ftsk 185
                  +  ++  +a+q+ ++++  +++++ H d+ + NvL+++ +   +sDf  + +     +d+        +++  +  ++apE + e         ++ +
   EEA21466.1 118 EDIEKKWIAFQLLCALRDCHAQEVFHGDIKTENVLVTSWNWLYLSDFSSSFKPtfLPEDNPadfsFYFDTSGRRTCYLAPERFLEAGeepgdrqVNWA 215
                  9999999****************************************965443222222222233334455567899999988766557777779*** PP

                  HHHHHHHHHHHHHHTTSSGTTTTSHHHHHHHHHHTTEES-B.BTTSBHHHHHHHHHHT-SSGGGS--HHH CS
  Pkinase_Tyr 186 sDvWsfGvllwEiftlgespypglkneevleklkegkrlek.pekcpeelyelmkkcweedpeeRptfse 254
                   D++s G ++ E+f   e p+ +l++   ++k + + + ++  +   +++ el+ +  + dpe+R + +e
   EEA21466.1 216 MDIFSAGCVIAELFL--EAPIFTLSQLYKYRKGEYSPEHSQlSKIEDSDVRELILHMIQIDPESRYSAEE 283
                  **************9..77776665555555543333333303334678999999999999999987665 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.7
                   EEEEEEEEESTTSSHHHHHHHHHHHHHHHTS.-BTTB- CS
  Pkinase_Tyr   28 evkVavKtlkeeateeekeelleeakimkkl.khpniv 64  
                    ++V  Kt  +  ++++++++++e++ ++++ + ++i 
   EEA21466.1  970 IERVTTKTSVDADRASDRSSIMTETDSLSRInSLNRIE 1007
                   56788999999999999***********9994444454 PP

>> Cnd1  non-SMC mitotic condensation complex subunit 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.2      0.17   2.6e+02      19      50 ..     431     462 ..     425     472 .. 0.85
   2 ?    1.6   0.0      0.17   2.5e+02      31      51 ..     492     512 ..     477     523 .. 0.86
   3 !   14.5   0.0   1.8e-05     0.027      17      71 ..     557     613 ..     550     616 .. 0.91

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.17
        Cnd1  19 veylvepLrkrLkDedpyVRktaaivvakLil 50 
                 ++ +++ + + L+D++  V+  a+ ++a+L++
  EEA21466.1 431 LDRILPYVMTMLNDRSDVVKVAAIRTLAQLLS 462
                 56778888999*****************9964 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.17
        Cnd1  31 kDedpyVRktaaivvakLiln 51 
                  D++p+VR   a +++ L + 
  EEA21466.1 492 FDPSPMVRAAYASCISSLAQS 512
                 59**************99665 PP

  == domain 3  score: 14.5 bits;  conditional E-value: 1.8e-05
        Cnd1  17 nlveylvepLrkrLkDedpyVRktaaivvakL.ilndmvkekg.flselaklleDen 71 
                 +l+ey+  + ++ L+D+dp VR+  +  v+ L +  +  k ++ +ls+l++ l+D++
  EEA21466.1 557 DLLEYFEIHTKALLTDSDPSVRRAFLGSVSSLcVFFGSTKINEvILSHLNTYLNDKD 613
                 789******************************77778888887***********87 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   0.0    0.0024       3.7       3      61 ..     437     512 ..     435     532 .. 0.67
   2 ?    4.6   0.0     0.029        43      39      77 ..     569     614 ..     554     624 .. 0.60
   3 ?    5.5   0.0     0.015        23       6      60 ..     607     668 ..     602     700 .. 0.73

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0024
      HEAT_2   3 aLlqalendpdpevrraairaLgrignp..................ealpaLvellededpavRraaaeaLgaigdp 61 
                 + +  l nd ++ v+ aair+L+++ +                   +++p + +   d++p+vR+a a  ++ ++ +
  EEA21466.1 437 YVMTML-NDRSDVVKVAAIRTLAQLLSLvqvvspvnayifpeyifpRLQPFVPDSSFDPSPMVRAAYASCISSLAQS 512
                 566778.9***************665555555557766666644445555555555679999**9999988877654 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.029
      HEAT_2  39 llededpavRraaaeaLg....aigd....pealpaLkelldddddd 77 
                 ll+d+dp vRra   + +     +g+    +  l++L  +l+d +d+
  EEA21466.1 569 LLTDSDPSVRRAFLGSVSslcvFFGStkinEVILSHLNTYLND-KDW 614
                 5588888888887777652222334322323356666666643.344 PP

  == domain 3  score: 5.5 bits;  conditional E-value: 0.015
      HEAT_2   6 qalendpdpevrraairaLg....rignpea....lpaLvellededpavRraaaeaLgaigd 60 
                  +l nd+d+ ++ a  +a       ig++++    lp++v+ l+d++  v + ++++++ ++d
  EEA21466.1 607 TYL-NDKDWILKCAFFEAVVgvaaYIGSTSLeefiLPLMVPSLTDTEDFVVERVIRSMASMAD 668
                 566.77788777776666665666777776666669999999***************998764 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.2   0.2   0.00013       0.2      26      55 .]     431     460 ..     414     460 .. 0.88
   2 ?   -2.1   0.0         4     6e+03      39      54 ..     493     508 ..     481     509 .. 0.81
   3 ?    4.1   0.0     0.046        69      29      53 ..     558     586 ..     554     588 .. 0.75
   4 ?   -0.0   0.0      0.91   1.4e+03      27      44 ..     638     655 ..     623     664 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00013
     HEAT_EZ  26 vpeilpaLlalLnddsdeVRaaAagaLgnl 55 
                 +++ilp+ + +Lnd sd V+ aA+++L++l
  EEA21466.1 431 LDRILPYVMTMLNDRSDVVKVAAIRTLAQL 460
                 679************************997 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 4
     HEAT_EZ  39 ddsdeVRaaAagaLgn 54 
                 d+s++VRaa a +++ 
  EEA21466.1 493 DPSPMVRAAYASCISS 508
                 7999999998877776 PP

  == domain 3  score: 4.1 bits;  conditional E-value: 0.046
     HEAT_EZ  29 ilpaLl....alLnddsdeVRaaAagaLg 53 
                 +l ++     alL+d++++VR a +g  +
  EEA21466.1 558 LLEYFEihtkALLTDSDPSVRRAFLGSVS 586
                 5555666666899********99887655 PP

  == domain 4  score: -0.0 bits;  conditional E-value: 0.91
     HEAT_EZ  27 peilpaLlalLnddsdeV 44 
                 + ilp++++ L+d +d V
  EEA21466.1 638 EFILPLMVPSLTDTEDFV 655
                 56999999*****99966 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   5.6e-05     0.084     187     248 ..    1140    1203 ..    1120    1224 .. 0.84
   2 ?   -0.8   0.0      0.39   5.8e+02     256     287 ..    1355    1386 ..    1347    1397 .. 0.81
   3 ?   -2.8   0.0       1.6   2.3e+03      53      93 ..    1583    1623 ..    1578    1624 .] 0.89

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 5.6e-05
    Ge1_WD40  187 hs.liveaafspdGtalatasedGevkffqvy.ledeeeprCLheWkPhdGkslssllfldnhk 248 
                  h+  i   +++pd +   tas dG+vk +    le++ +pr     +   G ++ +l f++n  
  EEA21466.1 1140 HTgPINRVVVAPDHAFFVTASDDGTVKVWDTTrLEKNLTPRSRQTHRHAPGTKVKCLTFVENTY 1203
                  44378889999******************987255667899988888888**********9975 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.39
    Ge1_WD40  256 WrfaitgadnnselklWscelWtClqtikfap 287 
                  W  +  g+ + se+ +W +e  +C    + a+
  EEA21466.1 1355 WVCVAGGSVHGSEITVWDVEKVQCREVYRAAS 1386
                  7777889999**************88777655 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 1.6
    Ge1_WD40   53 keteeraLlkglkgevldlafahvsskillavdekgslfvy 93  
                  ++++++ Llk   +++ld+a   v   + ++vd +g ++v+
  EEA21466.1 1583 ISLQQQQLLKSHLDSILDVAILRVPYGMTVSVDRAGMVYVF 1623
                  5788999***************99999999***99999998 PP

>> Tti2  Tti2 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   2.9e-05     0.044      95     155 ..     407     465 ..     384     475 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 2.9e-05
        Tti2  95 k.sgdlkaisvlawiirqlqskeieanwplivPpiLnllDdtdtsvKlrGlklLqtllekle 155
                 k s+++ka+++l    ++l ++   +++ +i P ++++l+d++  vK+ +++ L +ll+ ++
  EEA21466.1 407 KaSSKVKACDLLLAFAERLPDE---SKLDRILPYVMTMLNDRSDVVKVAAIRTLAQLLSLVQ 465
                 6688999999999999999999...7********************************9765 PP

>> RTP1_C1  Required for nuclear transport of RNA pol II C-terminus 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   0.1     0.016        23      33      71 ..     412     464 ..     389     478 .. 0.77
   2 ?    5.7   0.0     0.011        16      35      70 ..     634     669 ..     594     688 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.016
     RTP1_C1  33 e..............avldiekilkllleaLkdedsYvYLnaikgLvaLadvf 71 
                                +++++++il  ++++L+d  + v ++ai++L++L + +
  EEA21466.1 412 VkacdlllafaerlpDESKLDRILPYVMTMLNDRSDVVKVAAIRTLAQLLSLV 464
                 24444444444444489999****************************99875 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.011
     RTP1_C1  35 vldiekilkllleaLkdedsYvYLnaikgLvaLadv 70 
                 ++  e il l++ +L+d++++v   +i+ ++++ad 
  EEA21466.1 634 TSLEEFILPLMVPSLTDTEDFVVERVIRSMASMADL 669
                 56778999*************************995 PP

>> Cohesin_HEAT  HEAT repeat associated with sister chromatid cohesion
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   0.4     0.018        27      28      37 ..     492     501 ..     487     501 .. 0.90
   2 ?    6.7   0.1     0.006       8.9      27      37 ..     570     580 ..     567     582 .. 0.87

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.018
                   HSS-HHHHHH CS
  Cohesin_HEAT  28 tDsspsVRdA 37 
                    D+sp+VR+A
    EEA21466.1 492 FDPSPMVRAA 501
                   6*******98 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.006
                   HHSS-HHHHHH CS
  Cohesin_HEAT  27 ltDsspsVRdA 37 
                   ltDs+psVR A
    EEA21466.1 570 LTDSDPSVRRA 580
                   9********99 PP

>> MAP65_ASE1  Microtubule associated protein (MAP65/ASE1 family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   9.2    0.0063       9.5     405     549 ..     899    1053 ..     896    1080 .. 0.70

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0063
                  HHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHHHCXXXXXXXXXXXXXX...........XXXXXXXXXX..XXXXXXXXXXXXXXXXXXXXX CS
  MAP65_ASE1  405 leiieeqweeleekyqererqksarklkkasqteeeilkgskmrtpskrrvta...........pkTPsklksmskvsssssslkktpsnskslsan 490 
                  ++++ +++++ e+  + + + ++++++k+++ + + +     mrt s++ +t             +TP++ +  + ++++s+   +    s +++++
  EEA21466.1  899 ADALLDASTNVESAARRKHQRSATQRPKDSNPARRSLAIAGGMRTDSEAASTSsspiiqpashdSSTPNS-DIERVTTKTSVDADRASDRSSIMTET 994 
                  56667777778877788999999999*********************99999888888876654499994.66666666666766666777777777 PP

                  XX.XXXXXXXXXXXXXXXXXXXXX.XXX...XXXXXX................XXXXXXXXXX CS
  MAP65_ASE1  491 kn.talstanerkrklpsanvisk.nsaagrakrsllarlnskkasasan.q.nsskllrsPl 549 
                  ++ ++ ++ n+ ++k    n++++ ++a++ a      ++ns +a+ +   +  ++k++ sPl
  EEA21466.1  995 DSlSRINSLNRIEKKSGAINLLNRkETAKAFA----ETSMNSINAFGKVDvHsQQAKTSGSPL 1053
                  77888999999888888888888854443333....334456666655553135555555553 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1624 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       614  (0.0342462); expected 358.6 (0.02)
Passed bias filter:                      449  (0.0250432); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 1.02u 0.35s 00:00:01.37 Elapsed: 00:00:00.51
# Mc/sec: 9489.04
//
Query:       EEA21467.1  [L=923]
Description: DENN (AEX-3) domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.5e-40  137.9   0.0    7.3e-40  136.9   0.0    1.6  1  DENN            DENN (AEX-3) domain
    3.3e-06   27.7   0.0    1.1e-05   26.1   0.0    2.0  1  uDENN           uDENN domain
     0.0027   18.2   3.3     0.0027   18.2   3.3    2.3  2  Elongin_A       RNA polymerase II transcription factor SIII (
  ------ inclusion threshold ------
       0.28   11.3  15.3       0.38   10.9   4.0    2.7  2  BRE1            BRE1 E3 ubiquitin ligase
       0.57    9.4  13.8        0.4    9.9   1.9    2.6  2  DUF3450         Protein of unknown function (DUF3450)
          2    8.4  18.4       0.13   12.3   4.8    2.7  2  CENP-F_leu_zip  Leucine-rich repeats of kinetochore protein C


Domain annotation for each model (and alignments):
>> DENN  DENN (AEX-3) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  136.9   0.0   2.5e-43   7.3e-40       1     186 []     199     380 ..     199     380 .. 0.97

  Alignments for each domain:
  == domain 1  score: 136.9 bits;  conditional E-value: 2.5e-43
        DENN   1 yipkalcilsrlpffelfkkiLkalekrlkssskeaplesfianlllevplPapgktlklvslaveekillqrpe.dselPledvdlkelfrcLsieni 98 
                 +ip++l++lsr+p+++l+ ++L+ ++ ++++++  + +++  ++ +l++p P+ ++++++  ++++ ++++q+p+ ++ +  +++++++lf+cLsi+ni
  EEA21467.1 199 WIPYCLSFLSRYPLYDLLGDYLRGMWIHWNKAT--NLFHAEEVSRILSFPAPRLNDLVRI--DMKDYALCYQFPSsPTGF--QNFSMWPLFNCLSIPNI 291
                 89*******************************..9999999999***************..9************77788..***************** PP

        DENN  99 lqlfeavLl.ErriillSeklarLtsvaealvallyPlkWqhiyiPvlpaslldvl.eaPtPfiiGvesslleleekpledvvlvDldkn 186
                 + ++ea+++ +rrii++S+ +a+Lt +ae++  +++ ++W+++y+Pv++a++++ l e P P+i+G+  ++++ + + ++d ++vDld+n
  EEA21467.1 292 VGVIEAAVSpTRRIIFVSHYPAMLTIAAETIRFCVRVYEWSGLYVPVVHARHAKELvEEPGPYILGISPECRS-LFTAPSDALVVDLDRN 380
                 *********99***************************************9987655****************.**************86 PP

>> uDENN  uDENN domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.1   0.0   3.7e-09   1.1e-05       1      66 []     103     167 ..     103     167 .. 0.73

  Alignments for each domain:
  == domain 1  score: 26.1 bits;  conditional E-value: 3.7e-09
       uDENN   1 PevldryPpadhe.dfp.pedvpl.FcfPeglewsssteksserpepefFsFvLTdedgsrvYGaCltf 66 
                 Pe+l + P  +++ +++ + + ++  cfP+++  +++t k  ++p+  ++sFvL ++++ ++YG++l++
  EEA21467.1 103 PEILGSSPRLEQDnEIArSLHAAMrACFPHDV--EICTGK--SQPHCVHHSFVLQQDSSHTLYGIALRV 167
                 8888999996544223334445556*****98..554444..468999*******9999999****985 PP

>> Elongin_A  RNA polymerase II transcription factor SIII (Elongin) subunit A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   3.3   9.2e-07    0.0027      13     100 ..     483     575 ..     480     578 .. 0.83
   2 ?   -3.5   0.9         5   1.5e+04      19      28 ..     626     635 ..     610     649 .. 0.48

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 9.2e-07
   Elongin_A  13 rpiLekctpeqLreiEensphlaeetdelWkklikrdfpeesk.ekstepkep......kswrelYeklkkereeklkeaaerLreaykklkkek 100
                 +p++ k ++++L ei  + ++   +t e W+ +i+ + + +++  k+t+ +++      ++w++++ k++  +e+ l + + +L+ +++++k+e 
  EEA21467.1 483 KPLMTKVSMRHLNEIVRERNQYSRDTVEAWQDFINLKGRMDTElSKVTK-RNNflveelETWKQQFLKFQAFAEQ-LTKETSELKVKIEGHKREN 575
                 788889****************************888888877566666.5556888889*********877665.5566688999999998875 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 5
   Elongin_A  19 ctpeqLreiE 28 
                  + + L  +E
  EEA21467.1 626 RNQKELSAME 635
                 2223333333 PP

>> BRE1  BRE1 E3 ubiquitin ligase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   4.0   0.00013      0.38       7      90 ..     521     608 ..     520     613 .. 0.89
   2 ?    5.1   4.0    0.0077        23      11      88 ..     616     694 ..     606     699 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00013
        BRE1   7 klekafeelseqlskkvkeltileekklrleaekakadqkyfaamrskdalenelkkLnkllsKsselieqLke....lekefvrklk 90 
                 ++ ++  ++ + ++ +v+el+ ++++ l+ +a  ++  ++  +++ +++  + e+++L+ l++ +++ i++L      +ek+    l+
  EEA21467.1 521 RMDTELSKVTKRNNFLVEELETWKQQFLKFQAFAEQLTKETSELKVKIEGHKRENRRLTGLIDTQKDDITRLTLrlsgTEKQRDDALE 608
                 577888999999**********************************************************998777777776666555 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0077
        BRE1  11 afeelseqlskkvkeltileekklrleaekakadqkyfaamrskdalenelkkLnkllsKsselieqLke.lekefvrk 88 
                   eel+++ +  +kel+++e + + l+ + ++a++    ++  +d  +  + ++ ++l+ s++l e   + le++ +++
  EEA21467.1 616 IAEELERERKRNQKELSAMEHRTSTLTRQRDEAQRIVVHLRSLIDGQTHHMEHIIRNLASSTDLGEYIDQaLENSAQES 694
                 468899999999***********************************************99999999999777776655 PP

>> DUF3450  Protein of unknown function (DUF3450)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   1.9   0.00013       0.4      14      97 ..     522     605 ..     515     611 .. 0.86
   2 ?    4.0   6.2    0.0086        26      18      89 ..     603     674 ..     597     695 .. 0.53

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00013
     DUF3450  14 laatldqalkeaekavaaaaqsqkkidklddekqellaeyralkeeleslevyneqlerlvasqeqeiasleeqieeieeiere 97 
                 ++++l+++ k  +  v++ +   ++  k +  +++l +e  +lk ++e  + +n++l+ l+++q+ +i++l+ +++  e+ +++
  EEA21467.1 522 MDTELSKVTKRNNFLVEELETWKQQFLKFQAFAEQLTKETSELKVKIEGHKRENRRLTGLIDTQKDDITRLTLRLSGTEKQRDD 605
                 56677788888888888888888888999999999*************************************999999988876 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.0086
     DUF3450  18 ldqalkeaekavaaaaqsqkkidklddekqellaeyralkeeleslevyneqlerlvasqeqeiasleeqie 89 
                  d+al++    +++a++ +++ ++ ++e + ++ +  +l+++ ++++    +l++l++ q + ++ + ++++
  EEA21467.1 603 RDDALEALVLQQEIAEELERERKRNQKELSAMEHRTSTLTRQRDEAQRIVVHLRSLIDGQTHHMEHIIRNLA 674
                 344444444444555555555555555555555555555555555555555555555555555555555555 PP

>> CENP-F_leu_zip  Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   4.8   4.4e-05      0.13      28     108 ..     521     601 ..     511     609 .. 0.93
   2 ?   -0.1   6.9      0.28   8.4e+02      35      80 ..     612     657 ..     601     711 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 4.4e-05
  CENP-F_leu_zip  28 nLerelemseenqekvileaEtskaevetlkeeieelaeelreleldLvalrsekeeLekelqkkqervseLeslnsslen 108
                     +++ el  + + ++ ++ e Et k++  ++++  e+l++e++el+++++  ++e+  L+  + ++++ +  L  + s +e+
      EEA21467.1 521 RMDTELSKVTKRNNFLVEELETWKQQFLKFQAFAEQLTKETSELKVKIEGHKRENRRLTGLIDTQKDDITRLTLRLSGTEK 601
                     58899**************************************************************99999888777776 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.28
  CENP-F_leu_zip  35 mseenqekvileaEtskaevetlkeeieelaeelreleldLvalrs 80 
                      ++e  e++++e   +++e++++++   +l++++ e +  +v+lrs
      EEA21467.1 612 LQQEIAEELERERKRNQKELSAMEHRTSTLTRQRDEAQRIVVHLRS 657
                     3444445555555555555555555555555555555555555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (923 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1310  (0.073066); expected 358.6 (0.02)
Passed bias filter:                      515  (0.0287244); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.89u 0.34s 00:00:01.23 Elapsed: 00:00:00.51
# Mc/sec: 5474.48
//
Query:       EEA21468.1  [L=294]
Description: 3-oxoacyl-(acyl-carrier-protein) reductase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.4e-54  183.0   0.7    7.5e-54  182.7   0.7    1.0  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
    4.2e-42  143.8   0.1    5.7e-42  143.4   0.1    1.1  1  adh_short     short chain dehydrogenase
    1.6e-07   31.4   0.0    4.3e-07   30.0   0.0    1.6  1  KR            KR domain


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  182.7   0.7   1.3e-57   7.5e-54       5     234 .]      39     283 ..      34     283 .. 0.93

  Alignments for each domain:
  == domain 1  score: 182.7 bits;  conditional E-value: 1.3e-57
                   SHHHHHHHHHHHTT-E.EEEEESSGGH....HHHHHHHHHHTTSEEEE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHH CS
  adh_short_C2   5 gIGraiAkalaeeGae.vvltdlneea....kkrveelaeelgaevlecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreefd 96 
                   gIGra A+++a++Gae v l+d+++      k+++e+l  +++ ++ + D+ d  +v+a+v+++ +++g+lDi++ nagi+ + ++ f+e++ e+f 
    EEA21468.1  39 GIGRASAHQYARNGAEaVYLCDYDDTYlpthKREIESLYPDVEVQIRQFDAGDAPSVKAVVDDAIARYGRLDIMFANAGIVGS-TKLFTEIEPEDFM 134
                   9**************97999****9876334556666666666778************************************9.************* PP

                   HHHHHHTHHHHHHHHHHHHHCTSC........CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTT. CS
  adh_short_C2  97 raldvnlyslfllakaalplmkeg........gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikg. 184
                   ++l++n+ ++fl ak+a+p+m+ +        gsi++++sv++ r+ ++ + y+a+Kaa+++++++ +++l+  g+RvNa++pg+i+T +++ + + 
    EEA21468.1 135 KTLKTNTLGVFLAAKYAAPAMQITsvskpfpsGSIICTASVAGLRSNAGGTDYSASKAAVVNIAQTTCYQLAGTGVRVNAICPGVIETGMTKVMYDa 231
                   *******************998666788999***********************************************************9998885 PP

                   ..HHHHHHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEESTTGG CS
  adh_short_C2 185 ..fdelleelearaplgrlgtpeevaeaalfLasdeasyitGqtlvvDgGlt 234
                     ++  ++++ +  pl+r + ++eva++alfL sde+sy++Gq + v gGl+
    EEA21468.1 232 arARGTQDKIGQLNPLRRGAVADEVARVALFLGSDESSYMNGQAVTVCGGLS 283
                   4466699*******************************************86 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  143.4   0.1   9.6e-46   5.7e-42      11     190 ..      39     228 ..      37     233 .. 0.96

  Alignments for each domain:
  == domain 1  score: 143.4 bits;  conditional E-value: 9.6e-46
                 HHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHT..TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---S.S--SSGGGCSHHHHHHHH CS
   adh_short  11 GIGraiakelakeGakvvv.vdrseekleevakelkee..gakalaiqvDvtdreevealvekavkklgkldvLvnNAGi.tgsgpfselseeewervi 105
                 GIGra a+++a++Ga+ v  +d+ +  l + + e++++    ++ + q+D  d+ +v+a+v++a++++g+ld++ +NAGi   ++ f e++ e++ +++
  EEA21468.1  39 GIGRASAHQYARNGAEAVYlCDYDDTYLPTHKREIESLypDVEVQIRQFDAGDAPSVKAVVDDAIARYGRLDIMFANAGIvGSTKLFTEIEPEDFMKTL 137
                 9**************98888******************99999*************************************989999************* PP

                 HHHTHHHHHHHHHHHHHHH......HCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHH CS
   adh_short 106 evNltgvflltravlpaml......kqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakel 190
                 ++N  gvfl+++ ++pam          sG+I+ ++Svag+ ++ag++ YsAsKaav+ ++++   +la tg+rvna++PG+++T+m+k  
  EEA21468.1 138 KTNTLGVFLAAKYAAPAMQitsvskPFPSGSIICTASVAGLRSNAGGTDYSASKAAVVNIAQTTCYQLAGTGVRVNAICPGVIETGMTKVM 228
                 ******************99988655689**********************************************************9865 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.0   0.0   7.2e-11   4.3e-07      11     161 ..      39     199 ..      38     215 .. 0.85

  Alignments for each domain:
  == domain 1  score: 30.0 bits;  conditional E-value: 7.2e-11
                 HHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE------.---TTT--HHHHHHH CS
          KR  11 gLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlr.dklleemtaedleqv 108
                 g+G++ a++ a++ga+ + l+  + +  +++k++i++l   ++ev++++ D  d+ +v+a+++++ a+ +++   +  Ag++  +kl++e + ed+ + 
  EEA21468.1  39 GIGRASAHQYARNGAEAVYLCDYDDTYLPTHKREIESLYP-DVEVQIRQFDAGDAPSVKAVVDDAIARYGRLDIMFANAGIVGsTKLFTEIEPEDFMKT 136
                 79**********************9999999999998876.9**************************************9974678889999998876 PP

                 .........HTTTTHH.HHHHHHHTTTS--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHH CS
          KR 109 .........lapKvkG.awnLhelledesldffvlfSSiagllgsagqanYaaaNaflDalae 161
                          la+K ++ a ++  ++++ +   +++++S+agl  +ag ++Y+a  a +  +a+
  EEA21468.1 137 lktntlgvfLAAKYAApAMQITSVSKPFPSGSIICTASVAGLRSNAGGTDYSASKAAVVNIAQ 199
                 11111222256777654678888888899************************9887766665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (294 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       339  (0.0189079); expected 358.6 (0.02)
Passed bias filter:                      299  (0.0166769); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1967.32
//
Query:       EEA21469.1  [L=1104]
Description: TBC domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.1e-43  148.5   0.0    1.7e-42  145.5   0.0    2.1  1  RabGAP-TBC       Rab-GTPase-TBC domain
  ------ inclusion threshold ------
       0.16   12.4   0.0       0.44   11.0   0.0    1.7  1  Porphobil_deamC  Porphobilinogen deaminase, C-terminal domain


Domain annotation for each model (and alignments):
>> RabGAP-TBC  Rab-GTPase-TBC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.5   0.0   1.9e-46   1.7e-42       3     215 .]     799    1035 ..     798    1035 .. 0.88

  Alignments for each domain:
  == domain 1  score: 145.5 bits;  conditional E-value: 1.9e-46
  RabGAP-TBC    3 lRgevWklllgyepevkrlkksekkqeksekeksklekseeskelsqIkkDvprtfpesesfknkqgqnqLeriLkaysiynpevgYcqGmndivap 99  
                  +R+++W  ++g++             +++   +  +  + ++++  qI+ D+ rt++++ +f+n++g  +L+ +L+ays +npevgYcqGmn i++ 
  EEA21469.1  799 HRPKIWAECSGASA-------MRIPGYYDDLVNMVNVVDVDPTIVAQIDMDIYRTLTDNVFFRNGPGVAKLRDVLLAYSRRNPEVGYCQGMNLIAGS 888 
                  78888888888843.......22223444444555666777788*************88************************************** PP

  RabGAP-TBC  100 lllvsldeeeaFwcfvsLlekyklrdlytsslpglkrklkvleellkkkdpklykhlkeegldlelfaikwfltlflrefpletvlrlwD.lll... 192 
                  lll++   e+aFw+++s++e+  ++++y ++l   +++++vl++++ +++p+l+ hl+e+g++le  +++wfl +f+ +++ e + r+wD +l+   
  EEA21469.1  889 LLLTTPTAEDAFWIMTSMIENILPHHYYDHGLLASRADQQVLRQYITEVLPRLSAHLDELGIELEALTFQWFLSVFTDCLSAEALYRVWDvVLClnv 985 
                  **9999************************************************************************************7777876 PP

  RabGAP-TBC  193 .ege...........................kfvllrvalailklleeell 215 
                     +                           +++l++vala+lkl+e++ll
  EEA21469.1  986 tS-TtreragstviangpkkdaeedaasgggSTFLFQVALALLKLNEQQLL 1035
                  51.145567889999999999999999999977799999999999999986 PP

>> Porphobil_deamC  Porphobilinogen deaminase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   4.9e-05      0.44      16      56 ..    1036    1079 ..    1031    1088 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 4.9e-05
                       --TTSSEEEEEEEETTE....EEEEEEEE-TTS..S-EEEEEEE CS
  Porphobil_deamC   16 GGCsvPiGvyaeveane...elkLkglvlsldglksaveeaeak 56  
                         C++P +vy+ v+ ++    ++++gl+ + + l+++v++  + 
       EEA21469.1 1036 TTCQTPAAVYTYVNHQMtnhAISIDGLIQASEALRNVVRREDVV 1079
                       57***********95555789*************9988887665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1104 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       882  (0.049194); expected 358.6 (0.02)
Passed bias filter:                      456  (0.0254337); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.83u 0.28s 00:00:01.10 Elapsed: 00:00:00.46
# Mc/sec: 7247.95
//
Query:       EEA21470.1  [L=258]
Description: synaptobrevin-like protein Sybl1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.3e-32  108.7   0.0    1.2e-31  108.3   0.0    1.2  1  Synaptobrevin  Synaptobrevin
      1e-28   99.2   0.0    1.6e-28   98.6   0.0    1.3  1  Longin         Regulated-SNARE-like domain
  ------ inclusion threshold ------
       0.29   11.5   1.8       0.69   10.3   0.2    2.3  3  DUF4258        Domain of unknown function (DUF4258)


Domain annotation for each model (and alignments):
>> Synaptobrevin  Synaptobrevin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  108.3   0.0   2.1e-35   1.2e-31       3      89 .]     162     248 ..     160     248 .. 0.97

  Alignments for each domain:
  == domain 1  score: 108.3 bits;  conditional E-value: 2.1e-35
                    XHHHHHHHHHHCCCCHHCCHHHHCHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHTXXXXXXXXXXXXXXXXXXXXXXXX CS
  Synaptobrevin   3 dklakikaevdevkdimkeNidkvlergekldeLvdktenLqssaqqFkkqarklkrkmwwknmkliiililvvlililiiiivicg 89 
                    d+la +++e+d+v++im+eNi++vlerge++d+Lvdkt++L  +a +F+ ++r l+rkmwwkn+k++++l++vv++li++++ + cg
     EEA21470.1 162 DSLASARREIDSVRNIMTENIERVLERGERIDLLVDKTDRLGGTAHDFRMRSRGLRRKMWWKNVKVMVLLGVVVVFLIYLFVGMGCG 248
                    78999****************************************************************************998885 PP

>> Longin  Regulated-SNARE-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.6   0.0   2.6e-32   1.6e-28       1      83 [.      40     145 ..      40     146 .. 0.97

  Alignments for each domain:
  == domain 1  score: 98.6 bits;  conditional E-value: 2.6e-32
      Longin   1 aklilkkishsspqkltythdsytfhyla........................edgltylviadesyprrlaFafLeeikreFlakygtaktadaadlr 75 
                 a++il+kish++pqkltythd++++hy+a                        +++l+ylv+a+++++rr++FafL e kr+Fl++y++++t d+++l+
  EEA21470.1  40 ASIILPKISHDKPQKLTYTHDRLFVHYIAdspssgntqqddnsktpaggeldsHSSLSYLVVATAEQGRRIPFAFLLEAKRKFLSAYPPSTT-DFSALP 137
                 799************************************************9999*********************************9777.9***** PP

      Longin  76 pyafaeFd 83 
                 +y++a+++
  EEA21470.1 138 AYGCAAYN 145
                 *****998 PP

>> DUF4258  Domain of unknown function (DUF4258)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0       0.4   2.4e+03      18      34 ..      11      42 ..       8      67 .. 0.68
   2 ?   10.3   0.2   0.00011      0.69      11      27 ..     174     190 ..     165     204 .. 0.84
   3 ?   -2.3   0.2         1   6.1e+03       8      16 ..     210     218 ..     205     220 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.4
     DUF4258 18 dieevlenGe.iieeys..............l 34
                 + +++++G+ i  e+s              +
  EEA21470.1 11 FLYSCIAHGTtILAEHSspgasstsasslasI 42
                67889999987877777666655555555443 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00011
     DUF4258  11 eRgIseedieevlenGe 27 
                  R+I +e ie+vle+Ge
  EEA21470.1 174 VRNIMTENIERVLERGE 190
                 69**************8 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 1
     DUF4258   8 rmaeRgIse 16 
                 rm+ Rg+++
  EEA21470.1 210 RMRSRGLRR 218
                 9*****987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (258 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       960  (0.0535445); expected 358.6 (0.02)
Passed bias filter:                      794  (0.0442858); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 1771.15
//
Query:       EEA21471.1  [L=135]
Description: ribosomal protein L26 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.5e-39  132.1   3.1      1e-38  131.6   3.1    1.2  1  Ribosomal_L26  Ribosomal proteins L26 eukaryotic, L24P archae
    2.1e-07   30.6   1.2    5.2e-07   29.4   1.2    1.7  1  KOW            KOW motif
  ------ inclusion threshold ------
      0.048   13.7   0.1       0.06   13.4   0.1    1.2  1  DUF1223        Protein of unknown function (DUF1223)


Domain annotation for each model (and alignments):
>> Ribosomal_L26  Ribosomal proteins L26 eukaryotic, L24P archaeal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  131.6   3.1   1.7e-42     1e-38       2      81 ..      10     121 ..       9     122 .. 0.99

  Alignments for each domain:
  == domain 1  score: 131.6 bits;  conditional E-value: 1.7e-42
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................................xxxxxxxxxxxxxxxxxxxxxx RF
  Ribosomal_L26   2 ssrrkqrKahfnapshirrklmsapLskeLrekygvrslpir................................gvtrekangttvpvgihpSkvv 65 
                    ssrrk+rKahf+aps++rr +msapLskeLrek++vrs+pir                                +v rek+ng++vp+gihpSkvv
     EEA21471.1  10 SSRRKSRKAHFSAPSSERRVIMSAPLSKELREKHNVRSIPIRkddevtivrgsnkgregkvtsvyrlkyaihieRVVREKSNGQSVPLGIHPSKVV 105
                    89********************************************************************************************** PP

                    xxxxxxxxxxxxxxxx RF
  Ribosomal_L26  66 ItklklDkdrkkiLer 81 
                    ItklklDkdr+++Ler
     EEA21471.1 106 ITKLKLDKDRENLLER 121
                    **************98 PP

>> KOW  KOW motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.4   1.2   8.6e-11   5.2e-07       1      32 []      52      83 ..      52      86 .. 0.93

  Alignments for each domain:
  == domain 1  score: 29.4 bits;  conditional E-value: 8.6e-11
                TTSEEEESSSTTTTCEEEEEEEETTTTEEEEE CS
         KOW  1 pGdhVkVvsGphkGktGkVvkvdqhkvrVfvd 32
                ++d+V +v+G +kG++GkV++v++ k+ ++++
  EEA21471.1 52 KDDEVTIVRGSNKGREGKVTSVYRLKYAIHIE 83
                69************************888886 PP

>> DUF1223  Protein of unknown function (DUF1223)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.1     1e-05      0.06      94     166 ..       7      75 ..       2     102 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 1e-05
                 HHHHHHHTT-S--S-EEEEE-SS.SEEEEE---S....S-EEEEEEEEEEEEEEE---------EEEEEEEEE CS
     DUF1223  94 aisaaaaaaaaakvkvklsregdetlevsveaaaaseekeadvllvlvekeeevkvkrGeNagrtlthdnvvr 166
                 a++++++++++a++++ +s  ++ ++ +s+  ++ + +++++v  + ++k++ev++ rG N+gr+ + + v r
  EEA21471.1   7 AVASSRRKSRKAHFSAPSS--ER-RVIMSAPLSK-ELREKHNVRSIPIRKDDEVTIVRGSNKGREGKVTSVYR 75 
                 5555555544444444433..22.3333333333.24699************************988777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (135 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       357  (0.0199119); expected 358.6 (0.02)
Passed bias filter:                      244  (0.0136092); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.40u 0.23s 00:00:00.63 Elapsed: 00:00:00.40
# Mc/sec: 1021.52
//
Query:       EEA21472.1  [L=1266]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        7.3    7.3  10.6        2.5    8.8   1.0    3.3  3  FOXP-CC   FOXP coiled-coil domain


Domain annotation for each model (and alignments):
>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.2      0.39   6.9e+03      32      49 ..     317     334 ..     310     340 .. 0.77
   2 ?    8.8   1.0   0.00014       2.5       6      33 ..    1078    1105 ..    1074    1108 .. 0.90
   3 ?    4.6   0.1    0.0028        50       4      30 ..    1106    1134 ..    1103    1138 .. 0.83

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 0.39
     FOXP-CC  32 lddkstaqlrvqmqvvqq 49 
                  +++  aq++vq + v  
  EEA21472.1 317 RKKEVEAQTQVQAEAVAR 334
                 5667789*****999976 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.00014
     FOXP-CC    6 vCkWPgCekvledveeflkhlnseHald 33  
                  +C+W  C + l+dv+++ +h+ ++H  +
  EEA21472.1 1078 TCEWASCPAQLHDVHTLERHVVKNHISG 1105
                  7************************766 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.0028
     FOXP-CC    4 kgvCkWPgCekvledv..eeflkhlnseH 30  
                  + +C W +C ++++++  e + +hl ++H
  EEA21472.1 1106 QTTCLWQNCPNLATEYsgEGLKEHLAQAH 1134
                  568**********9983346999999999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1266 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1534  (0.0855597); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 1.03u 0.32s 00:00:01.35 Elapsed: 00:00:00.52
# Mc/sec: 7380.64
//
Query:       EEA21473.1  [L=74]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.6e-19   68.3   0.4    4.8e-19   67.9   0.4    1.2  1  Ost4           Oligosaccaryltransferase
  ------ inclusion threshold ------
       0.15   11.0   0.0       0.16   11.0   0.0    1.1  1  Acyl_transf_3  Acyltransferase family


Domain annotation for each model (and alignments):
>> Ost4  Oligosaccaryltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.9   0.4   5.4e-23   4.8e-19       1      34 []       1      34 [.       1      34 [. 0.98

  Alignments for each domain:
  == domain 1  score: 67.9 bits;  conditional E-value: 5.4e-23
                X-SHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS- CS
        Ost4  1 MIsDnqLytLAnfLGsaamlLIVlYHflevnakk 34
                MIsD++L +LA+fLGs+amlLIVlYHflevnak+
  EEA21473.1  1 MISDDDLFRLAIFLGSCAMLLIVLYHFLEVNAKD 34
                ********************************96 PP

>> Acyl_transf_3  Acyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   1.7e-05      0.16      10      40 ..      17      47 ..      14      68 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 1.7e-05
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Acyl_transf_3 10 iAillVvflHaliayspdagrgspiqasqss 40
                   +A+ll+v++H+l +   d ++ s+++ s++s
     EEA21473.1 17 CAMLLIVLYHFLEVNAKDESQDSLSTSSTTS 47
                   6********************9999988876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (74 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       557  (0.031067); expected 358.6 (0.02)
Passed bias filter:                      410  (0.022868); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.37u 0.27s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 538.68
//
Query:       EEA21474.1  [L=645]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.1e-16   58.5   0.0    8.1e-16   57.8   0.0    1.3  1  Fungal_trans  Fungal specific transcription factor domain
      1e-09   38.4   5.0    1.5e-09   37.8   5.0    1.3  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.058   12.7   0.2        0.1   12.0   0.2    1.3  1  TPR_MalT      MalT-like TPR region
      0.073   13.0   0.1        5.5    7.0   0.0    2.5  2  DUF4357       Domain of unknown function (DUF4357)


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.8   0.0   1.8e-19   8.1e-16       2     196 ..     220     385 ..     219     453 .. 0.75

  Alignments for each domain:
  == domain 1  score: 57.8 bits;  conditional E-value: 1.8e-19
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayasplll.lailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsL 97 
                   d+f snfhp  p+l  p  ++k+          ++p  l l+i  +Ga+f++ ++ e                +r++ ++ +     ++  + +q+L
    EEA21474.1 220 DVFYSNFHPAHPFLPPPGMFYKY----------SPPPYLeLVIKFIGAHFTPAASPEP---------------YRQSVVS-TTVGQDPC-PEKVQAL 289
                   89***************999999..........6666666**************9884...............3888888.45555555.7****** PP

  Fungal_trans  98 lllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrpp.llddsqinlpLPcddddlw 193
                   lll +++  + +r  +  ++  av+la++lg+hr+++ ++       ++  +es rR+ww  F+++ ++     r++ + ++  +++pLPc+++ ++
    EEA21474.1 290 LLLTIVLHSRNERQEAGELLAQAVSLAYDLGMHRKEYAEN----MAEDPIRRESFRRTWWELFVIEGMLTALGIRTSfTASEVPLEVPLPCEERIYQ 382
                   ****************************************....4466666***************9987766666668999999999****99655 PP

  Fungal_trans 194 esd 196
                   + +
    EEA21474.1 383 DGL 385
                   544 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.8   5.0   3.4e-13   1.5e-09       2      38 ..      71     106 ..      70     108 .. 0.94

  Alignments for each domain:
  == domain 1  score: 37.8 bits;  conditional E-value: 3.4e-13
                 S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCC CS
     Zn_clus   2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfysessk 38 
                 aC  Cr+k+ KCd+++P C++C++ +l C+ y+ s++
  EEA21474.1  71 ACLACRQKHLKCDGRQPICGRCQSGELACE-YTPSRR 106
                 9*****************************.998876 PP

>> TPR_MalT  MalT-like TPR region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.2   2.2e-05       0.1     280     317 ..     286     323 ..     282     324 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 2.2e-05
    TPR_MalT 280 ieiliLqalalqaqgreeeAlaaLeqALeLAepegyir 317
                 +++l+L++++l+ +++++eA + L+qA++LA++ g+ r
  EEA21474.1 286 VQALLLLTIVLHSRNERQEAGELLAQAVSLAYDLGMHR 323
                 7899****************************999866 PP

>> DUF4357  Domain of unknown function (DUF4357)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0     0.017        76      12      30 ..     395     414 ..     392     426 .. 0.82
   2 ?    7.0   0.0    0.0012       5.5      19      39 ..     489     509 ..     475     510 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.017
     DUF4357  12 ke.ggllvfteDyeFsSPSa 30 
                 k+ ++++  +eD++FsS S 
  EEA21474.1 395 KQfDDRIFAEEDITFSSFSY 414
                 4559999**********885 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0012
     DUF4357  19 fteDyeFsSPSaAAsvvlGrs 39 
                 f +  + sSP  AA+v++G+s
  EEA21474.1 489 FPRSDLLSSPAVAAEVICGHS 509
                 5556678************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (645 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       576  (0.0321267); expected 358.6 (0.02)
Passed bias filter:                      459  (0.025601); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.46
# Mc/sec: 4241.68
//
Query:       EEA21475.1  [L=56]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (56 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       555  (0.0309554); expected 358.6 (0.02)
Passed bias filter:                      236  (0.013163); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.36u 0.26s 00:00:00.62 Elapsed: 00:00:00.41
# Mc/sec: 408.05
//
Query:       EEA21476.1  [L=56]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (56 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       555  (0.0309554); expected 358.6 (0.02)
Passed bias filter:                      236  (0.013163); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.33u 0.23s 00:00:00.56 Elapsed: 00:00:00.39
# Mc/sec: 432.86
//
Query:       EEA21477.1  [L=809]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (809 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1353  (0.0754643); expected 358.6 (0.02)
Passed bias filter:                      789  (0.0440069); expected 358.6 (0.02)
Passed Vit filter:                        71  (0.00396006); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.79u 0.33s 00:00:01.12 Elapsed: 00:00:00.49
# Mc/sec: 4993.65
//
Query:       EEA21478.1  [L=342]
Description: hypothetical protein PMAA_052870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-07   31.7   0.0    2.3e-07   30.6   0.0    1.6  2  ApbA             Ketopantoate reductase PanE/ApbA
  ------ inclusion threshold ------
      0.049   12.9   0.1      0.075   12.3   0.1    1.3  1  FAD_binding_3    FAD binding domain
      0.074   12.5   0.0       0.11   11.9   0.0    1.2  1  AAA-ATPase_like  Predicted AAA-ATPase
       0.11   12.6   0.0       0.26   11.5   0.0    1.5  1  Enolase_N        Enolase, N-terminal domain


Domain annotation for each model (and alignments):
>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.6   0.0   5.2e-11   2.3e-07       1      78 [.       6      85 ..       6     108 .. 0.86
   2 ?   -3.0   0.0       1.1   5.2e+03      36      61 ..     254     279 ..     245     288 .. 0.65

  Alignments for each domain:
  == domain 1  score: 30.6 bits;  conditional E-value: 5.2e-11
                EEEES-SHHHHHHHHHHHHHTHCEEEE-SCHHHHHHHHHCEEEEETT.CEEEEEECEEECCH.SCCCCS-ESEEEE-SSG CS
        ApbA  1 iailGaGaiGsllaakLakagadvtlilrsrrlealkknGlrltseg.geeilrppealsae.ekselepidlvivtvKa 78
                ++i+GaGa+G + ++ L+ aga++t+++r  r+eal++  +  +  + + + +++ + l+++ ++ ++e +d +++t+  
  EEA21478.1  6 VLIAGAGAMGMITGYILSLAGAEITFLVRPHRAEALNHPQVLYYYIDnKLKEFKEYTYLTDPpQILDKEAYDFIVITLDG 85
                68************************************9999888887777777777777778899999*****999755 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.1
                 HHHHCEEEEETTCEEEEEECEEECCH CS
        ApbA  36 lkknGlrltseggeeilrppealsae 61 
                  + +Gl++++e g++ +++++++s +
  EEA21478.1 254 KEIQGLSIHGELGQQAAKTTTEASIA 279
                 45578888888888888877777655 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.1   1.7e-05     0.075       3      32 ..       5      34 ..       3      47 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.7e-05
                   EEEEE--SHHHHHHHHHHHHTTHHEEEEES CS
  FAD_binding_3  3 dVlIVGaGpaGlmlallLseaGvrvvlvek 32
                    VlI GaG  G++++ +Ls aG + + + +
     EEA21478.1  5 RVLIAGAGAMGMITGYILSLAGAEITFLVR 34
                   69********************99665543 PP

>> AAA-ATPase_like  Predicted AAA-ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   2.5e-05      0.11      21     109 ..      18     107 ..      17     118 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 2.5e-05
  AAA-ATPase_like  21 telieelveegkyyflsRPRRFGKsLll.stLeayfdgkkelFkg.laiekletkwke.knkypvlkldfsavkleseeeleeslkeklkel 109
                      t +i +l+  ++ +fl+RP+R   +L+  ++L +y d+k + Fk+ +++++ ++ +++    ++v++ld +a k e  ++l +++ + +++ 
       EEA21478.1  18 TGYILSLA-GAEITFLVRPHRA-EALNHpQVLYYYIDNKLKEFKEyTYLTDPPQILDKeAYDFIVITLDGAALKNEAGQNLVKTIGSAVRQS 107
                      67888887.56677*******6.566651667777778878887637899999977541457788899989999899999999988877765 PP

>> Enolase_N  Enolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   5.7e-05      0.26      81     126 ..      70     115 ..      62     119 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 5.7e-05
                 TT-HHHHHHHHHHHH-STT-TTT-HHHHHHHHHHHHHHHHHHHTS- CS
   Enolase_N  81 vtdqeeiDkllielDgtenksklGaNailavSlAvakaaAkakelp 126
                 ++d+e+ D ++i lDg+  k++ G N +  +  Av +  A+  ++ 
  EEA21478.1  70 ILDKEAYDFIVITLDGAALKNEAGQNLVKTIGSAVRQSTARNTGII 115
                 6789999*********************************998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       353  (0.0196888); expected 358.6 (0.02)
Passed bias filter:                      329  (0.0183502); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 2255.08
//
Query:       EEA21479.1  [L=86]
Description: hypothetical protein PMAA_052880 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (86 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       310  (0.0172904); expected 358.6 (0.02)
Passed bias filter:                      249  (0.0138881); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.36u 0.29s 00:00:00.64 Elapsed: 00:00:00.42
# Mc/sec: 615.79
//
Query:       EEA21480.1  [L=999]
Description: integral membrane channel protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.3e-06   27.0  28.3    3.6e-06   26.4  28.3    1.3  1  Ion_trans    Ion transport protein


Domain annotation for each model (and alignments):
>> Ion_trans  Ion transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.4  28.3     2e-10   3.6e-06      16     242 ..     343     559 ..     333     562 .. 0.75

  Alignments for each domain:
  == domain 1  score: 26.4 bits;  conditional E-value: 2e-10
                 HHHHHCCCSSSSHHHHC.HHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHCHSHHHHHHHHHHHHHHHHH.......HHHH..........HHHHHHH CS
   Ion_trans  16 cvflaletyfpedelek.tileilelvftaiftlemllkilalgllikkrYlrdpwnilDflvvlpsllsl.......vlse..........eslllls 96 
                 +v+l+l  +   +++   t +e++ +++ a f+l+ ++ +  +g+     Yl ++wn++D+ ++l+ +                        +++ +ls
  EEA21480.1 343 AVLLCLYLAVLIERSLHiTTVEVVFWLWSAGFMLDEIVGFNEQGF---SLYLMSFWNLFDLGILLLLFCYSilrlyvmA--MpdvrqlaaanQAYDILS 436
                 3333333333333333358899999999*****************...99*************9998884335555441..144556677775555555 PP

                 HHHHHGGGGGGHHHCHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSCCCCCCSCCSTSSSTTTSSSSSSHHHHHHHHHHHHTTSSH CS
   Ion_trans  97 vlrlfrvlrllklisrleglrtlvtalirsvkdllnvlllllvvlfifaligvqlfkgklreknecaktwenpnngntnFdnfftallwlfrlmttegw 195
                 +  ++ + rl+ ++ + + ++ l+ a+  ++ dl+ v+ll++v  + f +++   f                   +  + ++  + +++lf+++   g+
  EEA21480.1 437 AGAVLLFPRLFSVLDHYKYFSQLLIAFRIMAADLMAVFLLIVVACSGFLVAF--SF-------------------SSVSSQSPQEVIYALFQILM--GF 512
                 55555556666666666666667779***********************999..55...................34455667777777777555..88 PP

                 HHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Ion_trans 196 gdilyatldekskvaliyfvifiilgsflllNlliaviadnfqelte 242
                 +   +    e ++++ i++ +f++++ f+++ +li v +++f ++ +
  EEA21480.1 513 TPTAWSLWEEYNSLGRIILTVFLFICHFVVVTILITVLTNSFMSIVK 559
                 8888888888899999**************************88765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (999 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1064  (0.0593452); expected 358.6 (0.02)
Passed bias filter:                      467  (0.0260472); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.79u 0.26s 00:00:01.05 Elapsed: 00:00:00.44
# Mc/sec: 6842.88
//
Query:       EEA21481.1  [L=2263]
Description: bifunctional pyrimidine biosynthesis protein (PyrABCN), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   2.5e-114  380.0   0.1    3.2e-84  281.7   0.0    2.3  2  CPSase_L_D2      Carbamoyl-phosphate synthase L chain, ATP bi
    3.5e-48  162.7   0.0    7.1e-48  161.7   0.0    1.5  1  CPSase_sm_chain  Carbamoyl-phosphate synthase small chain, CP
    3.3e-47  160.7   0.0    8.6e-47  159.4   0.0    1.8  1  GATase           Glutamine amidotransferase class-I
    1.1e-45  155.3   0.0    2.3e-45  154.3   0.0    1.6  1  OTCace_N         Aspartate/ornithine carbamoyltransferase, ca
      5e-39  133.4   0.0    1.2e-38  132.2   0.0    1.7  1  CPSase_L_D3      Carbamoyl-phosphate synthetase large chain, 
    8.7e-31  107.1   0.0    2.2e-30  105.8   0.0    1.8  1  OTCace           Aspartate/ornithine carbamoyltransferase, As
      2e-22   79.2   0.0    7.6e-22   77.3   0.0    2.1  1  MGS              MGS-like domain
    1.1e-16   61.0   0.4    1.1e-07   31.7   0.1    2.5  2  Dala_Dala_lig_C  D-ala D-ala ligase C-terminus
    1.1e-15   57.6   0.1    3.1e-07   30.1   0.0    2.5  2  ATP-grasp        ATP-grasp domain
    1.7e-09   37.5   0.0    0.00035   20.3   0.0    2.5  2  ATPgrasp_Ter     ATP-grasp in the biosynthetic pathway with T
      1e-05   25.4   0.5    0.00074   19.3   0.5    2.5  1  Peptidase_C26    Peptidase C26
    1.5e-05   25.1   0.3      0.094   12.8   0.0    2.9  3  ATP-grasp_3      ATP-grasp domain
    9.6e-05   22.2   0.0      0.096   12.5   0.0    4.3  4  DJ-1_PfpI        DJ-1/PfpI family
     0.0014   18.3   0.0       0.82    9.2   0.0    2.6  2  RimK             RimK-like ATP-grasp domain
     0.0026   17.6   0.3        2.6    7.8   0.0    2.8  3  GARS_A           Phosphoribosylglycinamide synthetase, ATP-gr


Domain annotation for each model (and alignments):
>> CPSase_L_D2  Carbamoyl-phosphate synthase L chain, ATP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  281.7   0.0   2.7e-87   3.2e-84       1     210 [.     606     809 ..     606     810 .. 0.99
   2 !   96.4   0.1   1.4e-30   1.6e-27       2     209 ..    1143    1343 ..    1142    1345 .. 0.91

  Alignments for each domain:
  == domain 1  score: 281.7 bits;  conditional E-value: 2.7e-87
                  SHHHHHHHHHHTT-BBSSEECSSBSSHHHHHHHHHHH-SSEEEEETTCCTTTTEEEESSHHHHHHHHHHHHHHHHHHHSTS-EEEEE--SSSEEEEEE CS
  CPSase_L_D2   1 DkesakealkkinvpvvpssaapvetleealaiakeigyPviikaafglGGkGmrvarneeelaelvkkalaeakaafgnkqvlvekslkgpkeiEve 98 
                  D+e +++ ++ i++++++s++a  ++++ea++++k+ig+Pvi++aa++lGG+G+++a++ ++l+el++ka+a++      +qvl+e+s+kg+keiE+e
   EEA21481.1 606 DRELFARSMESIGEKCAKSASA--SNIDEAMEVVKDIGFPVIVRAAYALGGLGSGFAEDPKQLRELCTKAFAAS------PQVLIERSMKGWKEIEYE 695
                  9*********************..*************************************************9......8***************** PP

                  EEEETTS-EEEEEEEEECCEC..TCCCCEEEES-SS--HHHHHHHHHHHHHHHHHHT-EEEEEEEEEEETTTTEEEEEEEESS--CCHHHHHHHHS-- CS
  CPSase_L_D2  99 vlrDakgnvitvcerenslql..rtqkvievAPsqtLtdeerqalreaavkvvrevgvvgagtveflldpkskeyyviEvNtRlsvesalaekaTGld 194
                  v+rDa++n+itvc++en+++l  +t+++i+vAPsqtL+de++++lr++av+v+r++gvvg+++++++l+p+skey++iEvN+Rls++sala+kaTG++
   EEA21481.1 696 VVRDAQDNCITVCNMENFDPLgiHTGDSIVVAPSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPFSKEYCIIEVNARLSRSSALASKATGYP 793
                  ************************************************************************************************** PP

                  HHHHHHHHHTT--GCG CS
  CPSase_L_D2 195 lvkeaakialgekLee 210
                  l+++aak++lg++L+e
   EEA21481.1 794 LAFIAAKLGLGIPLNE 809
                  **************97 PP

  == domain 2  score: 96.4 bits;  conditional E-value: 1.4e-30
                   HHHHHHHHHHTT-BBSSEECSSBSSHHHHHHHHHHH-SSEEEEETTCCTTTTEEEESSHHHHHHHHHHHHHHHHHHHSTS-EEEEE--SSSEEEEE CS
  CPSase_L_D2    2 kesakealkkinvpvvpssaapvetleealaiakeigyPviikaafglGGkGmrvarneeelaelvkkalaeakaafgnkqvlvekslkgpkeiEv 97  
                   + +++++l++i+v+    ++   +++eea+a+ ++++yPv++++++ l G  m  ++++++la  +++a + ++    ++ v + k++++ keiE+
   EEA21481.1 1143 RYKFSRMLDRIGVDQPAWKEL--TSIEEATAFCDKVKYPVLVRPSYVLSGAAMNTVYSQDDLATYLQQAADVSR----EHPVVITKYIENAKEIEM 1232
                   667888899999887776666..9*************************************************6....9***************** PP

                   EEEEETTS-EEEEEEEEECCEC..TCCCCEEEES-SS--HHHHHHHHHHHHHHHHHHT-EEEEEEEEEEETTTTEEEEEEEESS--CCHHHHHHHH CS
  CPSase_L_D2   98 evlrDakgnvitvcerenslql..rtqkvievAPsqtLtdeerqalreaavkvvrevgvvgagtveflldpkskeyyviEvNtRlsvesalaekaT 191 
                   + ++ ++g ++  +  e + +   + ++   + P q L++e+ ++++ a+ k+ ++++v+g  +++f+ +  ++++ viE N R s++ +  +k+ 
   EEA21481.1 1233 DAVA-RNGVMVGHFISEHVENAgvHSGDATLILPPQDLDPETVRRIEDATRKIGNALNVTGPYNIQFIAK--DNDIKVIECNVRASRSFPFVSKVM 1325
                   **98.4566666666666666667********************************************99..69********************** PP

                   S--HHHHHHHHHTT--GC CS
  CPSase_L_D2  192 GldlvkeaakialgekLe 209 
                   G+dl+++a k  +g++ +
   EEA21481.1 1326 GVDLIEMATKAMMGIPFQ 1343
                   **********99998876 PP

>> CPSase_sm_chain  Carbamoyl-phosphate synthase small chain, CPSase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  161.7   0.0   5.9e-51   7.1e-48       2     127 ..      67     206 ..      66     207 .. 0.90

  Alignments for each domain:
  == domain 1  score: 161.7 bits;  conditional E-value: 5.9e-51
  CPSase_sm_chain   2 avLvLedGtvfeGksfg.akeavGEvvfnTgmtGYqeiltDpsYagqilvltypliGnyGv.needves...........ekikvaglvvrels 82 
                      ++L LedGtv++G+sfg +k+++GE+vf+Tgm+GY+e++tDpsY+gqilv+t+pl+GnyGv ++e++++           ++i++a+lvv+++ 
       EEA21481.1  67 MALELEDGTVYQGYSFGaEKSVAGELVFQTGMVGYPESVTDPSYRGQILVITFPLVGNYGVpSRETMDEilkelpkhfesSQIHIAALVVASYF 160
                      5799*************77999***************************************83444444666666666669***********98 PP

  CPSase_sm_chain  83 e.epsnwraeesLsewlkeekipgisgvDTRaLtkklrekgamkgv 127
                        ++s++ a++sL +wlke+++p+++g+DTRaLtk++re+g+m+g+
       EEA21481.1 161 GeDYSHFLAKSSLGTWLKEQNVPAVYGIDTRALTKRIREEGSMLGR 206
                      659****************************************997 PP

>> GATase  Glutamine amidotransferase class-I
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  159.4   0.0   7.2e-50   8.6e-47       3     189 ..     276     452 ..     274     453 .. 0.94

  Alignments for each domain:
  == domain 1  score: 159.4 bits;  conditional E-value: 7.2e-50
                 EESSTSTHHHHHHHHHHTT-EEEEEETTSHHHHHHHTHHSTSEEEEEEESSCTT.TTTHHHHHHHHCT.STS-EEEETHHHHHHHHHTTTEEEEEECEE CS
      GATase   3 iDnydsvtenlvhalvelgvkvevvpidasaeeilellknpdgilvsgGpgspg.vegkieaikeare.nkiPiLGICLGmQllaiefgrkvvkekeke 99 
                 +D++  +++n +++l+++gv+v v+p+++++++     +++dg+++s+Gpg+p+ +  ++++i++  +  +iPi+GICLG+Qlla ++g++++k+k ++
  EEA21481.1 276 LDVG--MKYNQLRCLLSRGVEVLVIPWNYDFHTLA--GSEYDGLFLSNGPGDPAtIPAAVQNISKTVQeGRIPIFGICLGHQLLARAVGANTIKMK-FG 369
                 6777..9*************************995..79****************9999999887766499*************************.** PP

                 EEEEEEEEEETTTCGGTTTTSEEEEEEEEEEEEESGCHHHTTEEEEEEEETTEEEEEEEEETTTEEEESSBTTSTTSTTHHHHHHHHHHH CS
      GATase 100 hhggtmrlgddetallyglknevierhrHryevnpkelepaglevtakseddeelmeiiekknpfvgvQFHPEststpegpellfnflik 189
                 ++g+++++++        +++++i++++H+++v+  +++p+g+e ++++++d+++++i++ ++p+++vQFHPEst++p+++e+lf+ +i+
  EEA21481.1 370 NRGHNIPCTS------MISGKCHITSQNHGFAVDA-DTLPEGWEELFVNANDGSNEGIRHVSRPYFSVQFHPESTPGPRDTEYLFDVFIN 452
                 **********......55667*************8.**************************************************9986 PP

>> OTCace_N  Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  154.3   0.0   1.9e-48   2.3e-45       1     148 []    1962    2103 ..    1962    2103 .. 0.97

  Alignments for each domain:
  == domain 1  score: 154.3 bits;  conditional E-value: 1.9e-48
                  S-BSSGGGS-HHHHHHHHHHHHHHHHHHHTTT-STTTTT-EEEEEESS--HHHHHHHHHHHHHTTSEEEEEESTTTSCTTTGGSTTSSCHHHHHHHH CS
    OTCace_N    1 rhllsledlskeeieelldlaaelkekvkkekkekllkgktlallFeepStRTrvSfevAakrlGgkvlslseaediqlssvskgrkEsleDtarvl 97  
                  +h++s++++++++++ l+++a+e++  v+++   ++lkg++l++lF+epStRT++Sf++A++rlGg+++ +s++     ss++kg  E+l+Dt+r+l
  EEA21481.1 1962 KHVVSVSQFTRADLHLLFTVAQEMRLGVERQGVLDILKGRVLCTLFYEPSTRTSASFDAAMQRLGGRTIAISTE----HSSAKKG--ETLQDTIRTL 2052
                  79**********************************************************************55....7889999..********** PP

                  HHHTSEEEEEESSHHHHHHHHHHHSSEEEEEEETSSB-HHHHHHHHHHHHH CS
    OTCace_N   98 sryvdaiviRhpgaeeleelakyasvpviNagdgdgeHPtQaLaDlltire 148 
                  ++y+da+v+Rhp+++++++ ak++ vp+iN+g+g+ eHPtQa++Dl+tire
  EEA21481.1 2053 GCYGDAVVLRHPDEKSAHTAAKFSPVPIINGGNGSLEHPTQAFLDLFTIRE 2103
                  ************9999*********************************98 PP

>> CPSase_L_D3  Carbamoyl-phosphate synthetase large chain, oligomerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.2   0.0     1e-41   1.2e-38       2     122 .]     895    1016 ..     894    1016 .. 0.97

  Alignments for each domain:
  == domain 1  score: 132.2 bits;  conditional E-value: 1e-41
  CPSase_L_D3    2 elkeptdeRifaiaealrrglsveeiheltkidpwFLekleelvelekelkkkkk..eldeellreakklGfsDkqiaelleeeeeeevrelrkkl 95  
                   el++p+d+R+faia+a+++g+sv++i +lt+id+wFL+kl+ l ++ k+l++k +  +++ +l+r+ak+lGf D+q+a++l+ ++e ++r+lr ++
   EEA21481.1  895 ELQTPSDQRLFAIANAMHSGYSVDDIWKLTQIDKWFLRKLKGLSDFGKHLSAKYNatNVPVNLIRQAKQLGFADRQLAKFLS-SNELAIRRLRVEA 989 
                   799***********************************************99988889999*****************9976.88899******** PP

  CPSase_L_D3   96 gilpvykrvDtcAaeFeaetpYlYstY 122 
                   gi pv+k++Dt+AaeF+a+t+YlY tY
   EEA21481.1  990 GIIPVVKQIDTVAAEFPAYTNYLYLTY 1016
                   **************************9 PP

>> OTCace  Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  105.8   0.0   1.8e-33   2.2e-30       2     156 ..    2110    2259 ..    2109    2260 .. 0.91

  Alignments for each domain:
  == domain 1  score: 105.8 bits;  conditional E-value: 1.8e-33
                  C.EEEEESS.TTSHHHHHHHHHHHHCT-EEEEES-TTSSH-HHHHHHHHHHHHHHT-EEEEESSCH.HHHTT-SEEEE--SSETTCCGGHH...HHH CS
      OTCace    2 glkiafvGd.kknnvanslikllarlgmdvvlvaPkglepdkevleeakknakksggsititedle.eavkgaDvvytdvwvsmgeekere...erl 93  
                  gl+++fvGd k++++++slikll  +++ v+lvaPk+l+  ++    ++k + +sg+ +  +e+l+ e ++  Dv+y ++++     ker+   +++
  EEA21481.1 2110 GLTVTFVGDlKYGRTVHSLIKLLQFYDVRVQLVAPKALSLPED----VRKLVVSSGQLVCESEKLTpEIISRSDVLYCTRVQ-----KERFadlAEY 2197
                  89***********************************988444....4577777888887788777799*************.....7777677999 PP

                  HHHCC.CSB-HHHHHHS-TT-EEEE-S---BTTTB-HHHHTSTTBHHHHHHHHHHHHHHHHHHH CS
      OTCace   94 kklkd.yqvteellklakkdaivlHcLPakrgeEvtdeVfdsprsvvfeqaeNrlhtikAllvl 156 
                  + lkd + v++ +lk+ak++++v+H+LP  r+ E+ +eV+ ++r+++f+q++++l+ ++All+l
  EEA21481.1 2198 ERLKDsFVVDNSVLKHAKSHMVVMHPLP--RNAEIGEEVDFDQRAAYFRQMRYGLYCRMALLAL 2259
                  999*************************..********************************97 PP

>> MGS  MGS-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.3   0.0   6.3e-25   7.6e-22       1      95 []    1423    1521 ..    1423    1521 .. 0.98

  Alignments for each domain:
  == domain 1  score: 77.3 bits;  conditional E-value: 6.3e-25
                  THHHHHHHHHHTTCEEEEEHHHHHHHHHTT--EEECCCCHSTGSGGTHCHHHHHHHHTTSCCEEEEE--THHHHHH....CHHHHHHHHHHHTTSHE CS
         MGS    1 glvelakklkelgfellATgGTakllkeagipvtevvektgegerlggrveildaikngeidlvintlypfkatva....kdgykirraaenidIpl 93  
                  ++++ ++kl+++g++l+AT GTa+++ke+gipv+ ++ + ge+e l+ +++++++++n+ idl+in++++++ ++     ++gy++rr+a++++ pl
  EEA21481.1 1423 EMLPSIQKLHKMGYNLFATAGTADYIKEHGIPVKYLELLNGEEEDLKSEYSLTQHLANNLIDLYINLPSSNRYRRPanymSKGYRTRRMAVDYQTPL 1519
                  6899**********************************************************************999*******************9 PP

                  ES CS
         MGS   94 pt 95  
                  +t
  EEA21481.1 1520 VT 1521
                  98 PP

>> Dala_Dala_lig_C  D-ala D-ala ligase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.7   0.0   2.9e-09   3.5e-06      26     174 ..     631     777 ..     619     778 .. 0.86
   2 !   31.7   0.1   8.9e-11   1.1e-07      15     173 ..    1155    1311 ..    1149    1315 .. 0.85

  Alignments for each domain:
  == domain 1  score: 26.7 bits;  conditional E-value: 2.9e-09
                      HHHHHHHHHC-SSEEEEESSSSTTTTEEEESSGGGHHHHHHHHHTT-SCEEEEE--.ESEEEEEEEEETSSCEEEEEEEEE-SSSSS-HHHHHC CS
  Dala_Dala_lig_C  26 ellekveeelgypvfVKpareGSSvGvskveseeelkeaieeafkydekvlvEeai.egreievavlgneklevsevgeivvkkgfydyeakys 118
                      +   +v++ +g+pv+V++a +   +G   +e  ++l+e   +af    +vl+E+ +   +eie  v+ + + ++ +v ++    + +d    ++
       EEA21481.1 631 DEAMEVVKDIGFPVIVRAAYALGGLGSGFAEDPKQLRELCTKAFAASPQVLIERSMkGWKEIEYEVVRDAQDNCITVCNM----ENFDPLGIHT 720
                      4567899**************99*********************************6679********888888777655....4466666677 PP

                      .TT-EEESS----HHHHHHHHHHHHHHHHHTT--SEEEEEEEE.ETTTEEEEEEEES CS
  Dala_Dala_lig_C 119 ddkaqlevpaklekeveekiqelalkaykaldlrGlaRvDffl.teegeivlnEvNt 174
                      +d++ +    +l++e ++ ++++a+++ + l++ G + + + l   + e  + EvN 
       EEA21481.1 721 GDSIVVAPSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALnPFSKEYCIIEVNA 777
                      89999999999******************************9955688889999995 PP

  == domain 2  score: 31.7 bits;  conditional E-value: 8.9e-11
                       EETTHHCH-H-.HHHHHHHHHC-SSEEEEESSSSTTTTEEEESSGGGHHHHHHHHHT..T-SCEEEEE--.ESEEEEE.EEEETSSCEEEEE CS
  Dala_Dala_lig_C   15 lekeeakeekk.ellekveeelgypvfVKpareGSSvGvskveseeelkeaieeafk..ydekvlvEeai.egreiev.avlgneklevsev 101 
                       +++ ++ke ++ e  ++ +++++ypv+V+p+   S   ++ v s+++l+ ++++a+   +++ v++ ++i +++eie+ av  n+ +  + +
       EEA21481.1 1155 VDQPAWKELTSiEEATAFCDKVKYPVLVRPSYVLSGAAMNTVYSQDDLATYLQQAADvsREHPVVITKYIeNAKEIEMdAVARNGVMVGHFI 1246
                       4555555544435667889***********************************976116778*******99*****956777888888889 PP

                       EEEE-SSSSS-HHHHHC.TT-EEESS----HHHHHHHHHHHHHHHHHTT--SEEEEEEEEETTTEEEEEEEE CS
  Dala_Dala_lig_C  102 geivvkkgfydyeakysddkaqlevpaklekeveekiqelalkaykaldlrGlaRvDfflteegeivlnEvN 173 
                        e+v + g+       s+d++ +  p +l++e+ ++i+++  k+ +al+++G   + f+ + +++i + E N
       EEA21481.1 1247 SEHVENAGVH------SGDATLILPPQDLDPETVRRIEDATRKIGNALNVTGPYNIQFIAK-DNDIKVIECN 1311
                       9999988886......567888999*******************************99876.8888888888 PP

>> ATP-grasp  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.0   0.0     1e-08   1.2e-05       7     138 ..     620     756 ..     614     778 .. 0.87
   2 !   30.1   0.0   2.6e-10   3.1e-07       3     159 ..    1152    1313 ..    1150    1317 .. 0.84

  Alignments for each domain:
  == domain 1  score: 25.0 bits;  conditional E-value: 1e-08
                 -B-EEEEECCHHHHHHHHHHH-SCEEEEESSS-CTTTTEEEECTCCGHHCHHHHC..GTTCEEEEE----SEEEEEEEEEETTC-EEE--EEEEEEETT CS
   ATP-grasp   7 pvprflaveskeeleeaaeelglpvvvKarrlgydGkGqsvvrseedleqaleal..keekvivEefvpfekElsvlvvrsaeGetafypvvetvqedg 103
                 + ++ + +++ +e+ e+++++g+pv+v+ +  +  G G+ + +++++l+++ + +  ++ +v++E  ++  kE+   vvr+a+ +  ++  +e+    g
  EEA21481.1 620 KCAKSASASNIDEAMEVVKDIGFPVIVR-AAYALGGLGSGFAEDPKQLRELCTKAfaASPQVLIERSMKGWKEIEYEVVRDAQDNCITVCNMENFDPLG 717
                 67788899999*****************.8999*****************99988889999***********************999999999999888 PP

                 EEE...EEEECEE-.SCHHHHHHHHHHHHHHHHHTSSEE CS
   ATP-grasp 104 ilr...lsvapaev.sekaqkkaeeiakkiveeLggvGv 138
                 i     ++vap++  s+++ +  +++a +++++Lg+vG 
  EEA21481.1 718 IHTgdsIVVAPSQTlSDEDYNMLRTTAVNVIRHLGVVGE 756
                 8743337888877615557778888999*********95 PP

  == domain 2  score: 30.1 bits;  conditional E-value: 2.6e-10
                  TTT--B-EEEEECCHHHHHHHHHHH-SCEEEEESSS-CTTTTEEEECTCCGHHCHHHHC....GTTCEEEEE----SEEEEEEEEEETTC-EEE--E CS
   ATP-grasp    3 klglpvprflaveskeeleeaaeelglpvvvKarrlgydGkGqsvvrseedleqaleal....keekvivEefvpfekElsvlvvrsaeGetafypv 95  
                  + g+  p +  ++s ee+ ++++++++pv+v+ +    +G     v s++dl + l+++    +e++v++ ++++  kE+ +  + +++G ++   +
  EEA21481.1 1152 RIGVDQPAWKELTSIEEATAFCDKVKYPVLVR-PSYVLSGAAMNTVYSQDDLATYLQQAadvsREHPVVITKYIENAKEIEM-DAVARNGVMVGHFI 1246
                  678999**************************.99999*************98888877777799***************76.44456676655555 PP

                  EEEEE....ETTEEEEEEECEE-SCHHHHHHHHHHHHHHHHHTSSEEEEEEEEEETTCTEEEEEEESS CS
   ATP-grasp   96 vetvq....edgilrlsvapaevsekaqkkaeeiakkiveeLggvGvfavElFvledgellvnElapR 159 
                   e+v+    ++g+  l + p++++ +  +++e+ ++ki ++L++ G + + +  + d+++ v E   R
  EEA21481.1 1247 SEHVEnagvHSGDATLILPPQDLDPETVRRIEDATRKIGNALNVTGPYNIQFIAK-DNDIKVIECNVR 1313
                  55554111256788999*********************************86665.999999887776 PP

>> ATPgrasp_Ter  ATP-grasp in the biosynthetic pathway with Ter operon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   2.2e-05     0.026      49     123 ..     740     817 ..     729     823 .. 0.79
   2 !   20.3   0.0   2.9e-07   0.00035      49     118 ..    1277    1347 ..    1265    1359 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2.2e-05
  ATPgrasp_Ter  49 lielaerlaeefgldglvnvQvred..edgpkLLEiNpRasGGlg.ysalaGvnlpylalklllgleteeveepeegl 123
                   l   a ++++++g+ g  n+Q+  +   ++++++E+N+R s      s ++G  l+ +a+kl lg + +e+++  +++
    EEA21481.1 740 LRTTAVNVIRHLGVVGECNIQYALNpfSKEYCIIEVNARLSRSSAlASKATGYPLAFIAAKLGLGIPLNEIKNSVTKV 817
                   5567999**************988732455**********96555156777**************9888887766655 PP

  == domain 2  score: 20.3 bits;  conditional E-value: 2.9e-07
  ATPgrasp_Ter   49 lielaerlaeefgldglvnvQvrededgpkLLEiNpRasGGlg.ysalaGvnlpylalklllgleteevee 118 
                    + ++++++ ++++++g +n+Q+  +++  k++E N Ras  +  +s + Gv+l+++a k+++g + +e ++
    EEA21481.1 1277 IEDATRKIGNALNVTGPYNIQFIAKDNDIKVIECNVRASRSFPfVSKVMGVDLIEMATKAMMGIPFQEYPP 1347
                    557889999*******************************998357788**************86666554 PP

>> Peptidase_C26  Peptidase C26
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.5   6.2e-07   0.00074     100     216 .]     337     435 ..     330     435 .. 0.69

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 6.2e-07
  Peptidase_C26 100 aalergvPilgiCrGlqllnvalGGtlyqdieeqsgltdhreheqsaashavkvekgsllaellgseeievnslHhqaike..laeelrveAvae. 192
                     + e ++Pi+giC+G+qll+ a+G ++   i+++ g          +  h++  +  s+++  +      +   H +a++   l e+++   v + 
     EEA21481.1 337 TVQEGRIPIFGICLGHQLLARAVGANT---IKMKFG----------NRGHNIPCT--SMISGKCH----ITSQNHGFAVDAdtLPEGWEELFVNAn 413
                    556778*************99999765...554223..........445666543..33333222....334469999976669999986655544 PP

  Peptidase_C26 193 DgviEaieseeakafvlgvQwHPE 216
                    Dg  E i++ ++  ++++vQ+HPE
     EEA21481.1 414 DGSNEGIRHVSR--PYFSVQFHPE 435
                    999999999994..5889999999 PP

>> ATP-grasp_3  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0       5.3   6.3e+03     144     160 ..     517     533 ..     463     534 .. 0.78
   2 !    9.4   0.0   0.00084         1     113     159 ..     733     780 ..     625     782 .. 0.67
   3 !   12.8   0.0   7.9e-05     0.094       1     158 [.    1140    1314 ..    1140    1317 .. 0.76

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 5.3
                  ESS.SEEEEEEESS--G CS
  ATP-grasp_3 144 lkdeepyviEvNPRltt 160
                  lk+e++y i +NP + t
   EEA21481.1 517 LKEEGIYTILINPNIAT 533
                  67788888889887765 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.00084
                  ---HHHHHHHHHHHHHTTSTT--EEEEEEEEESS...SEEEEEEESS-- CS
  ATP-grasp_3 113 etelkeevvelaeevvekleglaGyvGvDlvlkd..eepyviEvNPRlt 159
                    e+ + ++++a +v+++l g++G   +   l+   +e ++iEvN+Rl 
   EEA21481.1 733 SDEDYNMLRTTAVNVIRHL-GVVGECNIQYALNPfsKEYCIIEVNARLS 780
                  3355777899999999999.99999999999998989**********85 PP

  == domain 3  score: 12.8 bits;  conditional E-value: 7.9e-05
                   HTSHHHHHHHHTTT.S---.........-EESS--....SSSEEEEESS-------B--SS--TTE...............EEEE---.SEEEEEE CS
  ATP-grasp_3    1 asdKlktykkLkeagvkvP.....tkleaeeleee....ekklvvKprdGaggesvrvveekeeaeaaieeve........lvqefie.GkplSvs 78  
                   a++ +k+ + L++ gv  P     t  + ee++      ++++ v p++   g ++  v  ++++ + +++ +        ++ ++ie  k++ ++
   EEA21481.1 1140 AENRYKFSRMLDRIGVDQPawkelT--SIEEATAFcdkvKYPVLVRPSYVLSGAAMNTVYSQDDLATYLQQAAdvsrehpvVITKYIEnAKEIEMD 1233
                   579999*************886332..33333222555599*******9999998888888888887888777889999999*****945899999 PP

                   EEE.SSSEEEEEEEEEEEET....TEEEEEEES-..---HHHHHHHHHHHHHTTST...T--EEEEEEEEESS.SEEEEEEESS- CS
  ATP-grasp_3   79 llsdgekvlvlavnrqliekaekefvyaGnvtpi..etelkeevvelaeevvekle...glaGyvGvDlvlkdeepyviEvNPRl 158 
                   +++ +  v v  +  +++   e+  v +G  t i  +++l+ e+v+ +e++++k+    ++ G   + ++ kd+++ viE N R 
   EEA21481.1 1234 AVARN-GVMVGHFISEHV---ENAGVHSGDATLIlpPQDLDPETVRRIEDATRKIGnalNVTGPYNIQFIAKDNDIKVIECNVRA 1314
                   99966.444444444444...446899999987722345588888889999988875557788888****************995 PP

>> DJ-1_PfpI  DJ-1/PfpI family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.5   0.0     8e-05     0.096      49     111 ..     299     359 ..     259     366 .. 0.80
   2 ?    2.4   0.0     0.099   1.2e+02      15      71 ..     509     573 ..     502     579 .. 0.79
   3 ?   -0.1   0.0       0.6   7.1e+02      17      77 ..    1051    1118 ..    1046    1127 .. 0.69
   4 ?   -0.8   0.0      0.97   1.2e+03      13      55 ..    1685    1731 ..    1677    1740 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 8e-05
                 E-SEEGGGCTCCG-SEEEE--BHHHHHHHHTSHHHHHHHHHHHHTT-EEEEETTTHHHHHHTT CS
   DJ-1_PfpI  49 tvdaslddvkaaeyDalvlpGGragperlrenekvvelvkefaekgklvaaICagpqlLaaag 111
                 + ++ +  ++ +eyD l l  G   p ++ +  +v+++ k++ e   +++ IC g qlLa+a 
  EEA21481.1 299 PWNYDFHTLAGSEYDGLFLSNGPGDPATIPA--AVQNISKTVQEGRIPIFGICLGHQLLARAV 359
                 446777778889**********999999986..7**************************985 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.099
                 HHHHHHHHHHHTTEEEEEEESSTSEEEETTS.......EEEE-SEEGGGCTCCG-SEEEE-.-BH CS
   DJ-1_PfpI  15 ElivpvdvlkragikvdvvsvdkeevkgsrG.......lkvtvdaslddvkaaeyDalvlp.GGr 71 
                   +  +++lk++gi + ++ ++  ++++s+G       l v +d + + +k+++ Da+ +  GG+
  EEA21481.1 509 SGSQAIKALKEEGIYTILINPNIATIQTSKGladkvyfLPVNADFVRKVIKHERPDAIYVTfGGQ 573
                 5567899************************8877766666777777788888888885532554 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.6
                  HHHHHHHHHTTEEEEEEESSTSEEEETTS.......EEEE-SEEGGGCTCCG-SEEEE.--BHHHHHHH CS
   DJ-1_PfpI   17 ivpvdvlkragikvdvvsvdkeevkgsrG.......lkvtvdaslddvkaaeyDalvl.pGGragperl 77  
                  + +++ l+++g+k+++v  + e+v++  +       +++ ++++ld  + ++   +++  GG++ p+++
  EEA21481.1 1051 VRTIRTLREQGYKTVMVNYNPETVSTDYDeadrlyfENINLETVLDIYQLESSSGVIMsMGGQT-PNNI 1118
                  567899**************99998877766666666666666666555554444444156655.6665 PP

  == domain 4  score: -0.8 bits;  conditional E-value: 0.97
                  HHHHHHHHHHHHHTTEEEEEEESS....TSEEEETTSEEEE-SEEGG CS
   DJ-1_PfpI   13 dvElivpvdvlkragikvdvvsvd....keevkgsrGlkvtvdasld 55  
                  d+  i +++ l +  i+v  vs +        +  +Glkvt+d+s+ 
  EEA21481.1 1685 DLASILLLASLHNRNIHVLNVSSKedinLIALSKEKGLKVTCDVSIY 1731
                  5556677888999999999999998765556688999*******996 PP

>> RimK  RimK-like ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.2   0.0    0.0058         7      22      69 ..     625     670 ..     609     697 .. 0.80
   2 !    9.2   0.0   0.00069      0.82       1     102 [.    1140    1244 ..    1140    1333 .. 0.82

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0058
                 EEESS-S-HHHHHHTT-.-SSEEEEE-TTTT--EEEEE-SHHHHHHHH CS
        RimK  22 alardeedaekliekiklrfPvvvKsvegsqGikvvlakkeqklkqvl 69 
                 a a + ++a ++++ i  +fPv+v+  ++  G++  +a+++++l+++ 
  EEA21481.1 625 ASASNIDEAMEVVKDI--GFPVIVRAAYALGGLGSGFAEDPKQLRELC 670
                 4455556666666666..7*************************9984 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00069
                  HH-HHHHHHHHHHTT-----EEEESS-S-HHHHHHTT-.-SSEEEEE-TTTT--EEEEE-SHHHHHHHHHH.....GGG--EEEEE--SS-SEEEEE CS
        RimK    1 ardKlkslklLakakikvpntalardeedaekliekiklrfPvvvKsvegsqGikvvlakkeqklkqvlea.....lkeailvqeyieeaenediRv 92  
                  a++++k  ++L + +++ p  +   + e+a+++ +k+  + Pv+v+ ++   G  +     +++l   l+       ++ +++ +yie+a++ ++  
  EEA21481.1 1140 AENRYKFSRMLDRIGVDQPAWKELTSIEEATAFCDKV--KYPVLVRPSYVLSGAAMNTVYSQDDLATYLQQaadvsREHPVVITKYIENAKEIEMDA 1234
                  67999999*****************************..59************99988888888887776556765556689********9999988 PP

                  EEETTEEEEE CS
        RimK   93 lvvddevvaa 102 
                  +  ++ +v+ 
  EEA21481.1 1235 VARNGVMVGH 1244
                  7777777765 PP

>> GARS_A  Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.5   0.0    0.0053       6.3      10     104 ..     614     702 ..     607     748 .. 0.77
   2 !    7.8   0.0    0.0021       2.6       8      90 ..    1148    1225 ..    1142    1248 .. 0.77
   3 ?   -3.4   0.0       5.9   7.1e+03     173     188 ..    1298    1313 ..    1289    1315 .. 0.78

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0053
                 HHHTT--B--EEEESSHHHHHHHHHHHSSSEEEEEESC-GGGT-EEEESSHHHHHHHHHHHCTS-TTCCCCSSEEEEE---S.EEEEEEEEECTTE CS
      GARS_A  10 lkkagiptaeyeaftdpeeakeyieeatakalVvKadglaagKgvivakseeealkavkeilekkkfGeagekvviEelleG.eEvsllalvdgkt 104
                 ++ +g + a+ ++ ++ +ea e++++ ++++ +v+a+   +g g   a++ +     ++e+ + k+f  a+ +v+iE  ++G +E+   ++ d ++
  EEA21481.1 614 MESIGEKCAKSASASNIDEAMEVVKDIGFPV-IVRAAYALGGLGSGFAEDPK----QLRELCT-KAFA-ASPQVLIERSMKGwKEIEYEVVRDAQD 702
                 778888999**********************.89988888888887776665....5666664.6665.99**********966888877777654 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0021
                  HHHHHTT--B--EEEESSHHHHHHHHHHHSSSEEEEEESC-GGGT-EEEESSHHHHHHHHHHHCTS-TTCCCCSSEEEEE--- CS
      GARS_A    8 dllkkagiptaeyeaftdpeeakeyieeatakalVvKadglaagKgvivakseeealkavkeilekkkfGeagekvviEelle 90  
                  ++l+++g+  + ++++t+ eea+++ ++++ ++  v+++ + +g  +  + s+++  +++++  +     + ++ vvi +++e
  EEA21481.1 1148 RMLDRIGVDQPAWKELTSIEEATAFCDKVKYPV-LVRPSYVLSGAAMNTVYSQDDLATYLQQAAD----VSREHPVVITKYIE 1225
                  5799*****************************.8899988888888777777776666665544....33456666666665 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 5.9
                  EEEETTEEEEEEEESS CS
      GARS_A  173 lmlvedgpkvlefnvR 188 
                  ++  ++  kv+e nvR
  EEA21481.1 1298 FIAKDNDIKVIECNVR 1313
                  55557779*******9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2263 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       459  (0.025601); expected 358.6 (0.02)
Passed bias filter:                      440  (0.0245412); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 1.11u 0.33s 00:00:01.44 Elapsed: 00:00:00.49
# Mc/sec: 13788.67
//
Query:       EEA21482.1  [L=445]
Description: hypothetical protein PMAA_052910 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
  ------ inclusion threshold ------
       0.51   10.1  10.1        0.1   12.4   2.6    2.8  3  DUF4393      Domain of unknown function (DUF4393)
          1    9.7   4.9       0.62   10.4   0.3    2.6  2  DUF1840      Domain of unknown function (DUF1840)
        2.9    6.8  12.1      0.063   12.3   2.0    2.3  2  DUF874       Helicobacter pylori protein of unknown function 


Domain annotation for each model (and alignments):
>> DUF4393  Domain of unknown function (DUF4393)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.2      0.15   9.1e+02      88     145 ..      86     141 ..      17     178 .. 0.59
   2 ?   12.4   2.6   1.7e-05       0.1      87     175 ..     278     372 ..     231     377 .. 0.70
   3 ?    4.2   0.8    0.0057        34     113     152 ..     362     401 ..     350     420 .. 0.73

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.15
     DUF4393  88 klekeeikeskesiknsfsdlhekvvlenpekvkasldnLerlgLiklsekqklteek 145
                 + +++++k++  +++ +++ ++++ ++++ ++     +   ++g   +se++++++++
  EEA21482.1  86 SSSEPNNKRQYTMTTTNSETSARSSIISQSQES--AKSTVSSVGVTSVSEDSQYSQKS 141
                 222224444444444444444444333333332..22334455555555555555554 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 1.7e-05
     DUF4393  87 ikleke.........eikeskesiknsfsdlhekvvlenpekvkasldnLerlgLiklsekqklteekvyeelenskiieelkeel..kkveqpkkidi 174
                   ++++         +i+++ ++++ +++        ++ +++++++d L + gLi+l e   ++ e +y ++++    +e+++ +  kk   ++++++
  EEA21482.1 278 TYAHSQrndfpntktDINNHLKILTAEINH-----LTKSNNNLSSCIDALGSSGLIDLLEMLSCSLERLYAAINSLRDEQEQQQDAasKKENSEQQLES 371
                 444444442333333444444444444443.....34557888*******************************9998888877777766666666666 PP

     DUF4393 175 t 175
                 +
  EEA21482.1 372 Q 372
                 5 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.0057
     DUF4393 113 vlenpekvkasldnLerlgLiklsekqklteekvyeelen 152
                 + ++ +++++ +++++rlg +  +++++l++e   ++ ++
  EEA21482.1 362 KENSEQQLESQIEIIQRLGFLLGQREEQLKHERKLNQSYR 401
                 34556788***********************986555444 PP

>> DUF1840  Domain of unknown function (DUF1840)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.5      0.15   8.7e+02      52      83 ..     130     161 ..      93     168 .. 0.64
   2 ?   10.4   0.3    0.0001      0.62      33      89 ..     324     379 ..     293     396 .. 0.75

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.15
     DUF1840  52 aiaaekaeeaeeeeeeeeeekeeekeeeeeev 83 
                  ++++++ ++++++++++++++++ e  +++ 
  EEA21482.1 130 SVSEDSQYSQKSAQQQRQHKQKRRGEGLKQAL 161
                 45555555555555555544444455555555 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.0001
     DUF1840  33 erGaita.edlpaaiakLeaaiaaekaeeaeeeeeeeeeekeeekeeeeeevsLaqRa 89 
                  +G i   e l   +++L aai++ ++e++++++ +++  ke+++++ e+++++ qR 
  EEA21482.1 324 SSGLIDLlEMLSCSLERLYAAINSLRDEQEQQQDAASK--KENSEQQLESQIEIIQRL 379
                 5566655144566799******9998887776666544..567899999999999997 PP

>> DUF874  Helicobacter pylori protein of unknown function (DUF874)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   2.0   1.1e-05     0.063      56     190 ..      13     154 ..       3     176 .. 0.62
   2 ?   -0.8   2.7     0.098   5.9e+02     144     203 ..     344     407 ..     327     417 .. 0.57

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.1e-05
      DUF874  56 lvkkhpkkssaalvvlthia.ckkakelddkvqdkskqa.ekenqinwwkysgltiaaslllaa.......csagdvdkqieleqekkkaeniedratk 145
                 l k++ kks  +l  l+hi+ c++        +d s  + ++   +n    s +ti as l  +        s    ++  +  q    + n e  a  
  EEA21482.1  13 LTKQQLKKSEDSL-ALSHISqCRN-EPSPTEGRDDSALSlKQIPSLNNNSISSFTIGASWLTKSnslhsssSSVYSSSEPNNKRQYTMTTTNSETSARS 109
                 6777778877776.5788862554.44444444444333033345666666666666666654400100004455555556666777789999999999 PP

      DUF874 146 sqikleqekqktnksnielansqikveqerqkteqekqkaekeai 190
                 s i   qe  k+  s++ ++      +  ++ ++q++q+ +k + 
  EEA21482.1 110 SIISQSQESAKSTVSSVGVTSVSEDSQYSQKSAQQQRQHKQKRRG 154
                 9****************9777665555555555666666555543 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.098
      DUF874 144 tksqikleqekqktnksnielansqikveqe....rqkteqekqkaekeaikleqekqktiktq 203
                 + ++++ eqe+q+   s+ e +++q+  + e          +++   k+  kl+q  +k i+  
  EEA21482.1 344 AINSLRDEQEQQQDAASKKENSEQQLESQIEiiqrLGFLLGQREEQLKHERKLNQSYRKNIEGL 407
                 4556666777777666666655554443333100033333344444455556666666666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (445 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2350  (0.131073); expected 358.6 (0.02)
Passed bias filter:                      533  (0.0297284); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.69u 0.30s 00:00:00.99 Elapsed: 00:00:00.45
# Mc/sec: 2951.42
//
Query:       EEA21483.1  [L=584]
Description: peroxisomal AMP binding enzyme, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.1e-81  272.2   0.0    7.6e-81  271.9   0.0    1.1  1  AMP-binding    AMP-binding enzyme
    1.1e-12   48.7   0.2      3e-12   47.3   0.1    1.8  2  AMP-binding_C  AMP-binding enzyme C-terminal domain


Domain annotation for each model (and alignments):
>> AMP-binding  AMP-binding enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  271.9   0.0   8.5e-85   7.6e-81       5     421 ..      74     484 ..      70     486 .. 0.84

  Alignments for each domain:
  == domain 1  score: 271.9 bits;  conditional E-value: 8.5e-85
                  HHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHH.HTTSSTT-E..EEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEEE CS
  AMP-binding   5 aaktpdkvalvdsgegqtlTYreldervnrlAagLr.slGvkkgdr..VaillpnspewvvallailkaGavvvplnptltaeelayiledseakvli 99 
                    +  +kva++ds +g+++TY++l + v++  ++L+ +l + + d   +a+l+pn++++vv+  a++ aG+v+vpl ++ + +el y + ds++++++
   EEA21483.1  74 STTDSKKVAVIDSTKGESFTYKQLLSDVSERKKWLLeQLSLADLDErrIAFLVPNGYDYVVMQWAVWAAGGVCVPLCTSHPVKELLYTIGDSQPSLVV 171
                  556679******999*********************999995544334************************************************** PP

                  ETCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHHHHCS CS
  AMP-binding 100 atvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkletrf 197
                    +        ++a +k+ ++ +++++   ++ +  +l ++ +    +  p+ +e+l  d  a++iYTSGTT +PKG++ +h+n+++++  l   + +
   EEA21483.1 172 --I--------HPAFDKVGTTLCELISN-VPFTEFIPLSSAMDITTIS-LPPFHESLPLDRRALMIYTSGTTSNPKGCVTTHKNITFQADCL--VKAW 255
                  ..3........44555544444444433.4444444444444444443.2446668999*****************************6665..4568 PP

                  CCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHH.C.....HHHHCCGTT-SEEE CS
  AMP-binding 198 klkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalk.a.....akkakdlsslrlvl 289
                  k +++d ++++lpl+h+ g++ +l +++lsGatv ++pk+++  + ++ +  +k + t++++vP+++ +l++  +         a +++  ++lrlv+
   EEA21483.1 256 KYTPSDHLIHVLPLHHVHGIVNGLTASFLSGATVEMYPKFDP--KIIWERWQDKGSSTMFMAVPTIYSRLVDYFDAHiRstdaeASSREGAKALRLVV 351
                  899***********************************9998..4467777888899*************66433332234443444446667***** PP

                  EESS-EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBEETTSE.EEEEEEETTS-SEBTT-HHHHH CS
  AMP-binding 290 lggeplspellrffralfgeevlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeetgepvpdgee.GellvrgpgvmkgYlkkpeata 386
                  +g ++l+  +  +f +++g+ +le YG+TE +++++ + l+ +++  gsvG+plpgv+v++ D et++ ++++ee G + ++g +v+  Y++kpeata
   EEA21483.1 352 SGSAALPTPIKAKFAEITGQVLLERYGMTEIGMAIS-CGLDVSRRLDGSVGWPLPGVQVRLTDKETNKIIEQNEEdGMIEIKGDNVFLEYWNKPEATA 448
                  ***********************************9.666777789*************************99999********************** PP

                  HHEEETCCEEEEEEEEEE.ETTSEEEEEEECC.CEEE CS
  AMP-binding 387 eafdsegrwlrTGDlgrl.dedGyleivgRkk.dlik 421
                  + f+ +++w++TGD++r+  edG ++i gR+  dlik
   EEA21483.1 449 KEFT-SDGWFKTGDVARRsKEDGAYYIQGRASvDLIK 484
                  ***9.757*********96899********7435555 PP

>> AMP-binding_C  AMP-binding enzyme C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.0         2   1.8e+04      28      39 ..     120     130 ..     118     143 .. 0.68
   2 !   47.3   0.1   3.4e-16     3e-12       1      76 []     494     570 ..     494     570 .. 0.94

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 2
                    --EEEEEE---- CS
  AMP-binding_C  28 alvafVvlkdgs 39 
                    + +af v++ g+
     EEA21483.1 120 RRIAFLVPN-GY 130
                    668999994.64 PP

  == domain 2  score: 47.3 bits;  conditional E-value: 3.4e-16
                    HHHHHHHSSTTEEEEEEE-----TTS---EEEEEE------.HHHHHHHHHHHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   1 evEsalvshpaVaeaaVvGvpdevkGealvafVvlkdgsea.leeeLkahvrkelgpyavpkkvvfvdelpktrsGK 76 
                    evE  ++  + ++e+aVvGv+de +G++++a++ l+dg e+    +L+ ++++e++py+ p  +++vd +++++ GK
     EEA21483.1 494 EVERKILGLEYIQEVAVVGVTDEEWGQRVAAVIKLRDGAEPlELSTLRTQLKQEMAPYKIPTILKLVDGIERNAMGK 570
                    8999*******************************9995343569*****************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (584 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       407  (0.0227007); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.47
# Mc/sec: 3721.21
//
Query:       EEA21484.1  [L=844]
Description: ABC transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.9e-24   84.7   0.1    2.8e-10   40.8   0.0    3.8  3  ABC_tran        ABC transporter
    1.2e-08   35.1   1.7     0.0014   18.5   0.1    3.9  4  AAA_21          AAA domain, putative AbiEii toxin, Type IV TA
      1e-06   28.9   0.0      0.064   13.5   0.0    2.7  2  SbcCD_C         Putative exonuclease SbcCD, C subunit
  ------ inclusion threshold ------
      0.019   14.7   0.0       0.11   12.2   0.0    2.2  2  AAA_29          P-loop containing region of AAA domain
      0.041   13.4   0.0      0.087   12.3   0.0    1.5  1  Ploopntkinase1  P-loop Nucleotide Kinase1
       0.22   11.4   6.5       0.35   10.7   6.5    1.3  1  Myc_N           Myc amino-terminal region
       0.36   10.1   9.2       0.63    9.3   9.2    1.3  1  NOA36           NOA36 protein
        2.7    7.7   9.2        8.1    6.2   9.2    1.8  1  Pox_Ag35        Pox virus Ag35 surface protein


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.7   0.0   2.5e-12   5.5e-09      79     136 ..     229     286 ..     191     287 .. 0.82
   2 !   40.8   0.0   1.3e-13   2.8e-10       6     136 ..     454     661 ..     451     662 .. 0.60
   3 ?   -2.4   0.0       2.7   6.1e+03     105     129 ..     771     795 ..     736     804 .. 0.75

  Alignments for each domain:
  == domain 1  score: 36.7 bits;  conditional E-value: 2.5e-12
                 H....HHHTCHHHHHHHSTTGGTTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 x....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  79 n....esdeeiekalsklglkelkdtvvksspssLSgGqkqrvalarallkkpkllllDEpt 136
                 n     +++++ek+++ ++l+el + +v    ssLS Gq +r  +a+all+ p+llllDEp+
  EEA21484.1 229 NtgkgFDEAQFEKVIKDFRLQELLELPV----SSLSNGQTRRTRIAKALLSSPELLLLDEPF 286
                 2556667899******************....*****************************6 PP

  == domain 2  score: 40.8 bits;  conditional E-value: 1.3e-13
                 EEEETTSEEEEEESTTSSHHHHHHHHTTSS--.SEEEE......EETTCEGGG......B-HHHCCHCEEEE-SS..--S-TTSBHHHH.......... CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxx......xxxxxxxxx......xxxxxxxxxxxxxxxx..xxxxxxxxxxxx.......... RF
    ABC_tran   6 lklkegekvaivGenGaGKStLlkllagllkp.teGei......lldgkdlke......qeleslrkeigvlpqe..pqlfpeltvren.......... 79 
                 +k+++g+++a++G nG+GK+tLl++++  + +  +  +      +              +++  l++++g  + e  +++ ++l++r +          
  EEA21484.1 454 WKVRQGQRWAVLGANGSGKTTLLSVMTSDHPQaYAQPVrmfgrsR------LPeqgvpgISIFDLQARMGHSSPEihAFFPRQLSIRASiesawadtfl 546
                 789***********************9987664555564444441......323444445555555555555444423333333344444444555566 PP

                 ......................................HHHTCHHHHHHHSTTGG..................................TTCBGESTTS CS
                 ......................................xxxxxxxxxxxxxxxxx..................................xxxxxxxxxx RF
    ABC_tran  80 ......................................esdeeiekalsklglke..................................lkdtvvkssp 106
                                                       e                                                       v++ +
  EEA21484.1 547 skpvltyerdtivdavleyfkpeldpsaediksnkasgE---------------AavdisfipatfratvaeaipvgnrstptpqyhpnH---DVDYAD 627
                 666665544555555666555555555444444455452...............033333333344444466666666777777775441...333332 PP

                 ....GGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 ....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran 107 ....ssLSgGqkqrvalarallkkpkllllDEpt 136
                      +LS  q++ +   ra++kk++l++lDE++
  EEA21484.1 628 nttfGQLSVAQQRLILFIRAIIKKQELIILDEAF 661
                 3335****************************97 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 2.7
                 TSGGS-HHHHHHHHHHHHHHHTSSE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran 105 spssLSgGqkqrvalarallkkpkl 129
                 s  +L  G++ r a+ r   +k kl
  EEA21484.1 771 SEGKLNDGERYRYAIPRKTQTKNKL 795
                 4478889999999998888877776 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.1   6.2e-07    0.0014     230     284 ..     252     303 ..     220     315 .. 0.88
   2 !   11.6   0.0   7.9e-05      0.18       4      19 ..     464     479 ..     463     504 .. 0.92
   3 ?    0.6   0.0      0.17   3.9e+02     219     265 ..     580     659 ..     518     664 .. 0.67
   4 ?   -1.1   0.2      0.57   1.3e+03     152     212 ..     755     816 ..     742     841 .. 0.66

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 6.2e-07
      AAA_21 230 qelparelSdGtkrllalltallralkkgsllliDEpEngLHPkllrrllellke 284
                  elp+++lS G+ r  +++ all+ +    lll+DEp  gL+P+ ++++  ll++
  EEA21484.1 252 LELPVSSLSNGQTRRTRIAKALLSSP---ELLLLDEPFMGLDPATTESISSLLRD 303
                 589********88888********99...9****************999988854 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 7.9e-05
      AAA_21   4 liGpNgsGKSnLLdal 19 
                 + G+NgsGK++LL  +
  EEA21484.1 464 VLGANGSGKTTLLSVM 479
                 78***********875 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.17
      AAA_21 219 r....................................gvvflengdgqelparelSdGtkrllalltallralkkgsllliDE 265
                 +                                    +   ++ ++  ++++ +lS  ++rl+ ++ a++       l+++DE
  EEA21484.1 580 NkasgeaavdisfipatfratvaeaipvgnrstptpqYHPNHDVDYADNTTFGQLSVAQQRLILFIRAIIKKQ---ELIILDE 659
                 44444445555555555555555555555555555545555677788899999*********99999998877...9999999 PP

  == domain 4  score: -1.1 bits;  conditional E-value: 0.57
      AAA_21 152 wsllllldglrke...rigllnifadyfgfakekrllqrlvrslklveielsdlgegeeliasv 212
                 ws ++l+ +++++     g ln+  +y +  ++k++++  +r l++  +e s+++e e  ++++
  EEA21484.1 755 WSENSLSKAMFLYgkdSEGKLNDGERYRYAIPRKTQTKNKLRALNDGPNEGSAEMEEE--HDDN 816
                 4444444444444777888888888999999999999988888888888888885433..2222 PP

>> SbcCD_C  Putative exonuclease SbcCD, C subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.5   0.0   5.7e-05      0.13      62      89 ..     275     302 ..     256     303 .. 0.87
   2 !   13.5   0.0   2.9e-05     0.064      64      89 ..     652     677 ..     645     678 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 5.7e-05
     SbcCD_C  62 palrlvfLDEAFsklDeesiatllelle 89 
                 ++++l++LDE F +lD+ +++++ +ll+
  EEA21484.1 275 SSPELLLLDEPFMGLDPATTESISSLLR 302
                 5699******************999987 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 2.9e-05
     SbcCD_C  64 lrlvfLDEAFsklDeesiatllelle 89 
                  +l++LDEAFs++ ++++++++ ll+
  EEA21484.1 652 QELIILDEAFSGMPANMREKCFYLLN 677
                 689******************99886 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   4.9e-05      0.11      18      39 ..     455     476 ..     446     488 .. 0.77
   2 ?   -1.2   0.0      0.79   1.8e+03      37      60 ..     557     585 ..     556     586 .. 0.63

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 4.9e-05
      AAA_29  18 eidlkg.atlltGpsGsGKSTll 39 
                 +++ +g    + G++GsGK+Tll
  EEA21484.1 455 KVR-QGqRWAVLGANGSGKTTLL 476
                 555.3447899***********9 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.79
      AAA_29  37 TllDAiqalLvpak.....kvrfNkaane 60 
                 T++DA+   + p+      +++ Nka++e
  EEA21484.1 557 TIVDAVLEYFKPELdpsaeDIKSNKASGE 585
                 78888877765543222257888888875 PP

>> Ploopntkinase1  P-loop Nucleotide Kinase1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   3.9e-05     0.087      16      46 ..     458     488 ..     454     499 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 3.9e-05
  Ploopntkinase1  16 rgelyyvkgsngsgkstvpsylaekdpeayv 46 
                     +g+ + v g+ngsgk+t+ s ++   p+ay 
      EEA21484.1 458 QGQRWAVLGANGSGKTTLLSVMTSDHPQAYA 488
                     6888999***********************6 PP

>> Myc_N  Myc amino-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   6.5   0.00016      0.35     217     266 ..     792     841 ..     766     844 .] 0.76

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00016
       Myc_N 217 aassssssdskalssseedvlsesdeeeeeeeeeeeeidVVtvekrrsss 266
                 +++ ++ +d  ++ s e++++++++eeeeee +ee+e++ V +ek++s +
  EEA21484.1 792 KNKLRALNDGPNEGSAEMEEEHDDNEEEEEEYDEEDEVEEVNIEKTESDK 841
                 44445555666667778888888889999999*************99665 PP

>> NOA36  NOA36 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   9.2   0.00028      0.63     226     301 ..     758     833 ..     744     842 .. 0.69

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00028
       NOA36 226 lslstrslkfgrqkqadgsddddddeedsdydaylkal.asgddeddegdedddddddeedddeeeddedeeeeeee 301
                  sls   + +g+++ +++ +d + + ++   ++++k+   + +d  +eg+ + ++++d+++++eee de++e ee +
  EEA21484.1 758 NSLSKAMFLYGKDS-EGKLNDGERYRYAIPRKTQTKNKlRALNDGPNEGSAEMEEEHDDNEEEEEEYDEEDEVEEVN 833
                 58888899999999.55777778799888877776664145577788888777777777777777666666655543 PP

>> Pox_Ag35  Pox virus Ag35 surface protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   9.2    0.0036       8.1      55     115 ..     781     842 ..     772     844 .] 0.70

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0036
    Pox_Ag35  55 krattprkkpakkek.kkkeeekeeaaeeeeledseedeenendedeseesvqaeeeksnes 115
                  r   prk+ +k++  + ++  +e  ae ee +d++e+ee+e de++  e+v++e+ +s+++
  EEA21484.1 781 YRYAIPRKTQTKNKLrALNDGPNEGSAEMEEEHDDNEEEEEEYDEEDEVEEVNIEKTESDKT 842
                 56677888866555404445555566777777888888888888888888888888888766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (844 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1011  (0.0563891); expected 358.6 (0.02)
Passed bias filter:                      654  (0.0364772); expected 358.6 (0.02)
Passed Vit filter:                       103  (0.00574488); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.82u 0.32s 00:00:01.13 Elapsed: 00:00:00.45
# Mc/sec: 5640.84
//
Query:       EEA21485.1  [L=445]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.7e-66  220.2   0.5    1.7e-16   60.5   0.1    6.1  6  Ank_2       Ankyrin repeats (3 copies)
    3.9e-56  186.4   4.2    3.6e-10   39.9   0.0    9.0  9  Ank_5       Ankyrin repeats (many copies)
    2.3e-51  165.8   0.1    0.00012   22.2   0.0   11.0 11  Ank_3       Ankyrin repeat
    3.8e-46  153.6   0.0    0.00025   21.4   0.0   10.4 10  Ank         Ankyrin repeat
      6e-42  141.5   0.2    1.7e-07   31.7   0.0    7.4  8  Ank_4       Ankyrin repeats (many copies)
  ------ inclusion threshold ------
      0.027   14.5   0.2        1.2    9.1   0.1    3.4  4  DGF-1_C     Dispersed gene family protein 1 of Trypanosoma cr
      0.031   14.1  15.2       0.79    9.6   0.2    6.9  8  VWA_3_C     von Willebrand factor type A C-terminal domain
      0.054   13.4   0.0       0.13   12.2   0.0    1.6  1  F-box_4     F-box
      0.064   13.2   0.0       0.16   11.9   0.0    1.7  1  F-box       F-box domain
      0.072   13.0   0.1       0.15   11.9   0.1    1.5  1  F-box-like  F-box-like
       0.12   12.9   0.3         18    5.8   0.0    4.2  5  3HCDH_RFF   3-hydroxybutyryl-CoA dehydrogenase reduced Rossma


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.1     0.033        53      27      66 ..      50      90 ..      35      99 .. 0.64
   2 !   52.0   0.0   4.9e-17     8e-14       2      83 .]      82     181 ..      81     181 .. 0.79
   3 !   35.3   0.0   7.7e-12   1.3e-08      26      83 .]     184     249 ..     174     249 .. 0.82
   4 !   40.1   0.0   2.6e-13   4.2e-10      20      79 ..     243     313 ..     240     317 .. 0.82
   5 !   60.5   0.1   1.1e-19   1.7e-16       1      83 []     290     385 ..     290     385 .. 0.80
   6 !   40.4   0.0     2e-13   3.2e-10      23      73 ..     382     441 ..     377     445 .] 0.78

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.033
       Ank_2 27 ktaLhyAakngnleivklLleh..adndgrtpLhyAarsghl 66
                 +aL  A +  +  + ++Ll +   +n + ++L +Aa++g  
  EEA21485.1 50 INALSQANRTLH-SFHSYLLYErnSRNGNGSALLWAAKHGIR 90
                456666655544.44588885543335555999999998864 PP

  == domain 2  score: 52.0 bits;  conditional E-value: 4.9e-17
       Ank_2   2 hlAakngnlelvklLl..egadpn...k.ngktaLhyAakngnleivklLle...h........adndgrtpLhyAarsghleivklLlekg.adinlk 82 
                  +Aak+g   + +  +   ++d+n   + +g++aL++Aa++g++++v lLl+            +d++grt++ +Aa++g++ +vklLle g ad++l+
  EEA21485.1  82 LWAAKHGIRATAEKSIwlGKCDINntiDeFGLNALIWAAREGHEDVVMLLLAlveTgrqvnvnfTDSNGRTAISWAAENGYETVVKLLLETGlADLELR 180
                 67888774456666666678***976538**********************96651556665566699*********************8854788776 PP

       Ank_2  83 d 83 
                 d
  EEA21485.1 181 D 181
                 5 PP

  == domain 3  score: 35.3 bits;  conditional E-value: 7.7e-12
       Ank_2  26 gktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlek.gadinlkd 83 
                  +++L yAa+ng++ +vkl+l+         d +g tp   Aa++gh  +v++Ll+   +d+n  d
  EEA21485.1 184 RMSPLSYAAENGHRTVVKLFLARdimnldsRDFTGSTPFSRAAENGHVAVVRMLLKTgRVDVNSED 249
                 489******************9667664544477*********************65467888765 PP

  == domain 4  score: 40.1 bits;  conditional E-value: 2.6e-13
       Ank_2  20 adpn..k.ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlek.gadi 79 
                 +d+n  + +g+t+L +Aa+ng++ +vk+Ll+        +d++ rtpL +A+ +gh  +v+ Ll+   +d 
  EEA21485.1 243 VDVNseDsEGRTPLSLAAENGHVVVVKMLLKTgrldidlQDSEARTPLSWASGNGHATVVRALLKDgRVDN 313
                 567764369************9999*****9677776666699*********************5524555 PP

  == domain 5  score: 60.5 bits;  conditional E-value: 1.1e-19
       Ank_2   1 LhlAakngnlelvklLl..egadpn.k..ngktaLhyAakngnleivklLle.h...ad...ndgrtpLhyAarsghleivklLl.ekgadinlkd 83 
                 L +A+ ng+  +v+ Ll    +d + k   g+t+L yA  +g++ +vk+Ll+ +   a+   ++grtpL +Aa++gh+ +vklLl +k +++++kd
  EEA21485.1 290 LSWASGNGHATVVRALLkdGRVDNDsKdsHGRTPLSYASAAGQEVVVKILLKlNevnANsedDNGRTPLSLAAENGHETVVKLLLkDKQVNVDTKD 385
                 6789999*99*******6444555462579************97779****9526554466799*********************55577777665 PP

  == domain 6  score: 40.4 bits;  conditional E-value: 2e-13
       Ank_2  23 n..k.ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLl 73 
                 +  + +g t+L +Aa ng+  +v+lLle         d+ g+tpL++A+ ++h e+vk Ll
  EEA21485.1 382 DtkDsKGSTPLSWAAGNGHPVVVRLLLETkrvdidsKDDAGWTPLFLAVVNNH-EAVKNLL 441
                 332359*************999*****9668664444488*********9999.9999776 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.1       1.2   1.9e+03      10      27 ..      72      88 ..      67      93 .. 0.78
   2 !   10.1   0.1    0.0005      0.81       9      36 ..     105     132 ..     101     133 .. 0.90
   3 !   19.9   0.0   4.2e-07   0.00068       1      46 [.     134     181 ..     134     182 .. 0.90
   4 !   20.0   0.0   3.9e-07   0.00064       1      38 [.     169     206 ..     169     210 .. 0.94
   5 !   32.5   0.0   4.5e-11   7.4e-08       7      56 .]     209     259 ..     205     259 .. 0.96
   6 !   37.5   0.0   1.2e-12     2e-09       1      53 [.     237     290 ..     237     291 .. 0.97
   7 !   36.4   0.0   2.8e-12   4.6e-09       9      56 .]     279     327 ..     278     327 .. 0.92
   8 !   31.4   0.0     1e-10   1.6e-07       7      53 ..     345     392 ..     339     392 .. 0.94
   9 !   39.9   0.0   2.2e-13   3.6e-10       1      53 [.     373     426 ..     372     429 .. 0.92

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 1.2
       Ank_5 10 nrldgggntpLhvAakyg 27
                n ++g+g ++L +Aak+g
  EEA21485.1 72 NSRNGNG-SALLWAAKHG 88
                6778888.99*****975 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.0005
       Ank_5   9 vnrldgggntpLhvAakygaadvvrlLl 36 
                 +n+ d++g ++L++Aa+ g+ dvv lLl
  EEA21485.1 105 NNTIDEFGLNALIWAAREGHEDVVMLLL 132
                 5899****************99998887 PP

  == domain 3  score: 19.9 bits;  conditional E-value: 4.2e-07
       Ank_5   1 Llehg.padvnrldgggntpLhvAakygaadvvrlLl.argadlnltd 46 
                 L+e g +++vn +d +g t++ +Aa++g+ +vv+lLl    adl l+d
  EEA21485.1 134 LVETGrQVNVNFTDSNGRTAISWAAENGYETVVKLLLeTGLADLELRD 181
                 8999*********************************77777766666 PP

  == domain 4  score: 20.0 bits;  conditional E-value: 3.9e-07
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlar 38 
                 Lle g ad+  +d  +++pL +Aa++g+ +vv+l+lar
  EEA21485.1 169 LLETGLADLELRDDLRMSPLSYAAENGHRTVVKLFLAR 206
                 89999*******************************66 PP

  == domain 5  score: 32.5 bits;  conditional E-value: 4.5e-11
       Ank_5   7 advnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltaldlA 56 
                 ++++ +d  g tp+  Aa++g+  vvr+Ll   ++d n  ds+G+t+l lA
  EEA21485.1 209 MNLDSRDFTGSTPFSRAAENGHVAVVRMLLkTGRVDVNSEDSEGRTPLSLA 259
                 588999******************************************998 PP

  == domain 6  score: 37.5 bits;  conditional E-value: 1.2e-12
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltal 53 
                 Ll+ g +dvn +d +g tpL +Aa++g+  vv++Ll   ++d++l+ds+ +t+l
  EEA21485.1 237 LLKTGRVDVNSEDSEGRTPLSLAAENGHVVVVKMLLkTGRLDIDLQDSEARTPL 290
                 788889***********************************************8 PP

  == domain 7  score: 36.4 bits;  conditional E-value: 2.8e-12
       Ank_5   9 vnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltaldlA 56 
                 ++ +d +  tpL +A+ +g+a+vvr Ll + ++d++ +ds+G+t+l +A
  EEA21485.1 279 IDLQDSEARTPLSWASGNGHATVVRALLkDGRVDNDSKDSHGRTPLSYA 327
                 566777778*************************************998 PP

  == domain 8  score: 31.4 bits;  conditional E-value: 1e-10
       Ank_5   7 advnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltal 53 
                 ++ n +d +g tpL +Aa++g+ +vv+lLl + +++ +++ds G+t+l
  EEA21485.1 345 VNANSEDDNGRTPLSLAAENGHETVVKLLLkDKQVNVDTKDSKGSTPL 392
                 899********************************************8 PP

  == domain 9  score: 39.9 bits;  conditional E-value: 2.2e-13
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltal 53 
                 Ll+  +++v+++d +g tpL +Aa +g++ vvrlLl   ++d++ +d+ G+t+l
  EEA21485.1 373 LLKDKQVNVDTKDSKGSTPLSWAAGNGHPVVVRLLLeTKRVDIDSKDDAGWTPL 426
                 455559***********************************************9 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0         2   3.3e+03       4      15 ..      79      90 ..      77     105 .. 0.72
   2 !    7.0   0.0    0.0064        10       2      23 ..     112     136 ..     111     145 .. 0.69
   3 !   14.8   0.0   1.9e-05     0.031       1      28 [.     149     176 ..     149     179 .. 0.89
   4 !   12.5   0.0    0.0001      0.17       3      26 ..     185     208 ..     184     213 .. 0.85
   5 !   18.8   0.0   9.5e-07    0.0015       2      30 ..     218     246 ..     217     247 .. 0.95
   6 !   19.6   0.0   5.2e-07   0.00085       1      29 [.     251     279 ..     251     281 .. 0.88
   7 !   13.5   0.0   5.2e-05     0.084       3      28 ..     287     312 ..     285     315 .. 0.88
   8 !   10.6   0.0   0.00044      0.72       1      29 [.     319     347 ..     319     349 .. 0.87
   9 !   22.2   0.0   7.4e-08   0.00012       1      30 [.     353     382 ..     353     383 .. 0.93
  10 !   19.4   0.0   5.9e-07   0.00096       2      30 ..     388     416 ..     387     417 .. 0.94
  11 !   11.7   0.0   0.00019      0.31       2      23 ..     422     442 ..     421     445 .] 0.85

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 2
       Ank_3  4 tpLhlAarsgnl 15
                ++L +Aa++g  
  EEA21485.1 79 SALLWAAKHGIR 90
                7999***99866 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0064
       Ank_3   2 GetpLhlAarsgnlei...vkfLle 23 
                 G ++L +Aar g+ ++   + +L+e
  EEA21485.1 112 GLNALIWAAREGHEDVvmlLLALVE 136
                 889************4234555555 PP

  == domain 3  score: 14.8 bits;  conditional E-value: 1.9e-05
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgad 28 
                 nG+t++ +Aa++g  ++vk+Lle   ad
  EEA21485.1 149 NGRTAISWAAENGYETVVKLLLETGLAD 176
                 7**********************66665 PP

  == domain 4  score: 12.5 bits;  conditional E-value: 0.0001
       Ank_3   3 etpLhlAarsgnleivkfLlenkg 26 
                 ++pL +Aa++g+ ++vk++l    
  EEA21485.1 185 MSPLSYAAENGHRTVVKLFLARDI 208
                 69*****************99544 PP

  == domain 5  score: 18.8 bits;  conditional E-value: 9.5e-07
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G tp+ +Aa++g++++v++Ll+   +dvn
  EEA21485.1 218 GSTPFSRAAENGHVAVVRMLLKTGRVDVN 246
                 89********************99***99 PP

  == domain 6  score: 19.6 bits;  conditional E-value: 5.2e-07
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadv 29 
                 +G+tpL lAa++g++ +vk+Ll+    d+
  EEA21485.1 251 EGRTPLSLAAENGHVVVVKMLLKTGRLDI 279
                 69********************9766666 PP

  == domain 7  score: 13.5 bits;  conditional E-value: 5.2e-05
       Ank_3   3 etpLhlAarsgnleivkfLlenkgad 28 
                 +tpL +A  +g+ ++v++Ll+   +d
  EEA21485.1 287 RTPLSWASGNGHATVVRALLKDGRVD 312
                 8*******************966665 PP

  == domain 8  score: 10.6 bits;  conditional E-value: 0.00044
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadv 29 
                 +G+tpL +A  +g   +vk Ll+ + ++ 
  EEA21485.1 319 HGRTPLSYASAAGQEVVVKILLKLNEVNA 347
                 79********************9555555 PP

  == domain 9  score: 22.2 bits;  conditional E-value: 7.4e-08
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvn 30 
                 nG+tpL lAa++g+ ++vk+Ll+ k ++v+
  EEA21485.1 353 NGRTPLSLAAENGHETVVKLLLKDKQVNVD 382
                 7**********************8888886 PP

  == domain 10  score: 19.4 bits;  conditional E-value: 5.9e-07
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G tpL +Aa +g++ +v++Lle k +d++
  EEA21485.1 388 GSTPLSWAAGNGHPVVVRLLLETKRVDID 416
                 89********************9999997 PP

  == domain 11  score: 11.7 bits;  conditional E-value: 0.00019
       Ank_3   2 GetpLhlAarsgnleivkfLle 23 
                 G+tpL+lA+ +++ + vk Ll 
  EEA21485.1 422 GWTPLFLAVVNNHEA-VKNLLL 442
                 9*************9.777765 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.0   0.0   0.00061         1       2      31 ..     112     147 ..     111     148 .. 0.80
   2 !   17.0   0.0   3.6e-06    0.0059       1      32 []     149     182 ..     149     182 .. 0.95
   3 !   10.2   0.0   0.00051      0.84       3      31 ..     185     215 ..     184     216 .. 0.80
   4 !   13.9   0.0   3.4e-05     0.055       2      31 ..     218     249 ..     217     250 .. 0.92
   5 !   19.0   0.0   8.7e-07    0.0014       2      31 ..     252     283 ..     251     284 .. 0.88
   6 !   11.2   0.0   0.00025       0.4       3      31 ..     287     317 ..     287     318 .. 0.86
   7 !   11.5   0.0   0.00019      0.32       1      27 [.     319     347 ..     319     352 .. 0.77
   8 !   21.4   0.0   1.5e-07   0.00025       1      31 [.     353     385 ..     353     386 .. 0.86
   9 !   16.3   0.0   5.9e-06    0.0097       2      32 .]     388     420 ..     387     420 .. 0.91
  10 !    9.1   0.0    0.0011       1.9       2      22 ..     422     441 ..     421     445 .] 0.80

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00061
                 SBBHHHHHHHHTTHHHHHHHH....TT..TSTTCBT CS
         Ank   2 GnTPLHlAatngkkriiklLL....hG..Anlnald 31 
                 G  +L +Aa++g+++++ lLL     G   n+n +d
  EEA21485.1 112 GLNALIWAAREGHEDVVMLLLalveTGrqVNVNFTD 147
                 6679***************98656547777888776 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 3.6e-06
                 TSBBHHHHHHHHTTHHHHHHHH.TT.TSTTCBTT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hG.Anlnaldn 32 
                 +G+T+  +Aa ng + ++klLL  G A+l ++d+
  EEA21485.1 149 NGRTAISWAAENGYETVVKLLLeTGlADLELRDD 182
                 7*********99**********99*****99995 PP

  == domain 3  score: 10.2 bits;  conditional E-value: 0.00051
                 BBHHHHHHHHTTHHHHHHHH.TT.TSTTCBT CS
         Ank   3 nTPLHlAatngkkriiklLL.hG.Anlnald 31 
                 ++PL +Aa ng+  ++kl+L +   nl+++d
  EEA21485.1 185 MSPLSYAAENGHRTVVKLFLaRDiMNLDSRD 215
                 68******************43345666666 PP

  == domain 4  score: 13.9 bits;  conditional E-value: 3.4e-05
                 SBBHHHHHHHHTTHHHHHHHH.TT.TSTTCBT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hG.Anlnald 31 
                 G TP  +Aa ng++ ++++LL  G  ++n+ d
  EEA21485.1 218 GSTPFSRAAENGHVAVVRMLLkTGrVDVNSED 249
                 88*******************8788****988 PP

  == domain 5  score: 19.0 bits;  conditional E-value: 8.7e-07
                 SBBHHHHHHHHTTHHHHHHHH.TT.TSTTCBT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hG.Anlnald 31 
                 G+TPL lAa ng++ ++k+LL  G  +++++d
  EEA21485.1 252 GRTPLSLAAENGHVVVVKMLLkTGrLDIDLQD 283
                 9********************87856888877 PP

  == domain 6  score: 11.2 bits;  conditional E-value: 0.00025
                 BBHHHHHHHHTTHHHHHHHH.TT.TSTTCBT CS
         Ank   3 nTPLHlAatngkkriiklLL.hG.Anlnald 31 
                 +TPL +A+ ng++ ++++LL +G  + +++d
  EEA21485.1 287 RTPLSWASGNGHATVVRALLkDGrVDNDSKD 317
                 5*******************88867766666 PP

  == domain 7  score: 11.5 bits;  conditional E-value: 0.00019
                 TSBBHHHHHHHHTTHHHHHHHH..TTTST CS
         Ank   1 dGnTPLHlAatngkkriiklLL..hGAnl 27 
                 +G+TPL +A+  g++ ++k LL  +  n 
  EEA21485.1 319 HGRTPLSYASAAGQEVVVKILLklNEVNA 347
                 69********999999*****94333333 PP

  == domain 8  score: 21.4 bits;  conditional E-value: 1.5e-07
                 TSBBHHHHHHHHTTHHHHHHHH.TT.TSTTCBT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hG.Anlnald 31 
                 +G+TPL lAa ng++ ++klLL +   n++ +d
  EEA21485.1 353 NGRTPLSLAAENGHETVVKLLLkDKqVNVDTKD 385
                 7*********************75347887776 PP

  == domain 9  score: 16.3 bits;  conditional E-value: 5.9e-06
                 SBBHHHHHHHHTTHHHHHHHH..TTTSTTCBTT CS
         Ank   2 GnTPLHlAatngkkriiklLL..hGAnlnaldn 32 
                 G TPL +Aa ng++ +++lLL  ++ +++++d+
  EEA21485.1 388 GSTPLSWAAGNGHPVVVRLLLetKRVDIDSKDD 420
                 89*******************9558***99995 PP

  == domain 10  score: 9.1 bits;  conditional E-value: 0.0011
                 SBBHHHHHHHHTTHHHHHHHH CS
         Ank   2 GnTPLHlAatngkkriiklLL 22 
                 G+TPL lA+  ++++ +k+LL
  EEA21485.1 422 GWTPLFLAV-VNNHEAVKNLL 441
                 9********.68888888776 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.1      0.46   7.6e+02      27      46 ..      68      88 ..      44      94 .. 0.76
   2 !   13.4   0.0   5.6e-05     0.091      25      55 .]     102     132 ..      95     132 .. 0.91
   3 !   28.4   0.0   1.1e-09   1.7e-06       2      55 .]     113     170 ..     112     170 .. 0.90
   4 !   24.1   0.0   2.4e-08   3.9e-05       1      55 []     150     204 ..     150     204 .. 0.95
   5 !   31.7   0.0     1e-10   1.7e-07       2      55 .]     219     272 ..     218     272 .. 0.95
   6 !   11.1   0.0   0.00029      0.48      16      55 .]     267     306 ..     267     306 .. 0.94
   7 !   27.2   0.0   2.6e-09   4.2e-06       1      55 []     320     374 ..     320     374 .. 0.89
   8 !   27.4   0.0   2.2e-09   3.6e-06       2      49 ..     389     436 ..     375     442 .. 0.92

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.46
       Ank_4 27 inaqdnrsGe.talhiAakrg 46
                ++++ +r+G+ +al  Aak+g
  EEA21485.1 68 LYERNSRNGNgSALLWAAKHG 88
                455545777778999999998 PP

  == domain 2  score: 13.4 bits;  conditional E-value: 5.6e-05
       Ank_4  25 adinaqdnrsGetalhiAakrgnveilklLl 55 
                  din ++++ G++al+ Aa+ g+ +++ lLl
  EEA21485.1 102 CDINNTIDEFGLNALIWAAREGHEDVVMLLL 132
                 79***********************998886 PP

  == domain 3  score: 28.4 bits;  conditional E-value: 1.1e-09
       Ank_4   2 ltaLhyaaisgrlelvrlLl...ekg..adinaqdnrsGetalhiAakrgnveilklLl 55 
                 l aL +aa +g++++v+lLl   e+g  +++n + +++G+ta+  Aa +g+  ++klLl
  EEA21485.1 113 LNALIWAAREGHEDVVMLLLalvETGrqVNVNFT-DSNGRTAISWAAENGYETVVKLLL 170
                 6799****************88866534888888.***********************8 PP

  == domain 4  score: 24.1 bits;  conditional E-value: 2.4e-08
       Ank_4   1 eltaLhyaaisgrlelvrlLlekg.adinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++ta+ +aa+ g + +v+lLle+g ad+  + ++  +++l +Aa +g+  ++kl+l
  EEA21485.1 150 GRTAISWAAENGYETVVKLLLETGlADLELR-DDLRMSPLSYAAENGHRTVVKLFL 204
                 589********************66******.999*******************97 PP

  == domain 5  score: 31.7 bits;  conditional E-value: 1e-10
       Ank_4   2 ltaLhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +t++ +aa+ g++ +vr Ll + ++d+n   +++G+t+l  Aa +g+v ++k+Ll
  EEA21485.1 219 STPFSRAAENGHVAVVRMLLKTgRVDVNSE-DSEGRTPLSLAAENGHVVVVKMLL 272
                 68999*****************77*****5.**********************98 PP

  == domain 6  score: 11.1 bits;  conditional E-value: 0.00029
       Ank_4  16 lvrlLlek.gadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +v+ Ll + + di+ q +++ +t+l  A  +g+  +++ Ll
  EEA21485.1 267 VVKMLLKTgRLDIDLQ-DSEARTPLSWASGNGHATVVRALL 306
                 5899****67******.*********************997 PP

  == domain 7  score: 27.2 bits;  conditional E-value: 2.6e-09
       Ank_4   1 eltaLhyaaisgrlelvrlLlekgadinaq.dnrsGetalhiAakrgnveilklLl 55 
                 ++t+L ya ++g++ +v++Ll k  ++na   +++G+t+l  Aa +g+  ++klLl
  EEA21485.1 320 GRTPLSYASAAGQEVVVKILL-KLNEVNANsEDDNGRTPLSLAAENGHETVVKLLL 374
                 589******************.5555555546899********************8 PP

  == domain 8  score: 27.4 bits;  conditional E-value: 2.2e-09
       Ank_4   2 ltaLhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAakrgnve 49 
                 +t+L +aa  g+  +vrlLle+ ++di+   ++ G+t+l  A+ +++  
  EEA21485.1 389 STPLSWAAGNGHPVVVRLLLETkRVDIDSK-DDAGWTPLFLAVVNNHEA 436
                 699******************978*****9.999*********988865 PP

>> DGF-1_C  Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.0       7.5   1.2e+04      29      46 ..     175     192 ..     167     195 .. 0.69
   2 ?    0.8   0.0       0.3   4.8e+02      29      52 ..     277     300 ..     267     304 .. 0.80
   3 ?    9.1   0.1   0.00076       1.2      19      48 ..     302     330 ..     296     336 .. 0.87
   4 ?   -0.9   0.0         1   1.6e+03      22      48 ..     372     398 ..     364     404 .. 0.81

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 7.5
     DGF-1_C  29 sdeelrklhdvtsssyas 46 
                 +d elr    ++ +sya+
  EEA21485.1 175 ADLELRDDLRMSPLSYAA 192
                 677777777888888886 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.3
     DGF-1_C  29 sdeelrklhdvtsssyasgttvas 52 
                  d +l+    +t +s+asg   a+
  EEA21485.1 277 LDIDLQDSEARTPLSWASGNGHAT 300
                 58899999***********98776 PP

  == domain 3  score: 9.1 bits;  conditional E-value: 0.00076
     DGF-1_C  19 leallrddeesdeelrklhdvtsssyasgt 48 
                 + all+d+   d++ +  h +t +syas +
  EEA21485.1 302 VRALLKDGR-VDNDSKDSHGRTPLSYASAA 330
                 679999987.89***************976 PP

  == domain 4  score: -0.9 bits;  conditional E-value: 1
     DGF-1_C  22 llrddeesdeelrklhdvtsssyasgt 48 
                 ll  d++ + +++  +  t +s+a+g 
  EEA21485.1 372 LLLKDKQVNVDTKDSKGSTPLSWAAGN 398
                 5556667889999**********9986 PP

>> VWA_3_C  von Willebrand factor type A C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0       0.2   3.3e+02       3      20 ..     119     136 ..     118     140 .. 0.85
   2 ?   -0.4   0.0      0.68   1.1e+03       3      15 ..     157     169 ..     156     171 .. 0.92
   3 ?   -1.8   0.0       1.8   2.9e+03       3      14 ..     191     202 ..     190     206 .. 0.88
   4 ?   -2.4   0.0       2.9   4.7e+03      38      46 ..     206     214 ..     204     214 .. 0.84
   5 ?    1.1   0.1      0.22   3.7e+02       3      19 ..     225     241 ..     224     250 .. 0.80
   6 ?    3.3   0.0     0.047        77       2      17 ..     258     273 ..     257     284 .. 0.92
   7 ?    1.7   0.1      0.15   2.4e+02       3      23 ..     327     346 ..     325     349 .. 0.88
   8 ?    9.6   0.2   0.00048      0.79       2      17 ..     360     375 ..     359     388 .. 0.76

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.2
                 HHHHT-HHHHHHHHTTEE CS
     VWA_3_C   3 AaeSGnedtaklLrkVVd 20 
                 Aa  G+ed + lL   V+
  EEA21485.1 119 AAREGHEDVVMLLLALVE 136
                 5667*********98887 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.68
                 HHHHT-HHHHHHH CS
     VWA_3_C   3 AaeSGnedtaklL 15 
                 Aae G e  +klL
  EEA21485.1 157 AAENGYETVVKLL 169
                 99**********9 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 1.8
                 HHHHT-HHHHHH CS
     VWA_3_C   3 AaeSGnedtakl 14 
                 Aae G+   +kl
  EEA21485.1 191 AAENGHRTVVKL 202
                 89*****99998 PP

  == domain 4  score: -2.4 bits;  conditional E-value: 2.9
                 HHHHHHHHH CS
     VWA_3_C  38 aDemaLDtr 46 
                  D m+LD r
  EEA21485.1 206 RDIMNLDSR 214
                 589****87 PP

  == domain 5  score: 1.1 bits;  conditional E-value: 0.22
                 HHHHT-HHHHHHHHTTE CS
     VWA_3_C   3 AaeSGnedtaklLrkVV 19 
                 Aae G+   +++L k  
  EEA21485.1 225 AAENGHVAVVRMLLKTG 241
                 89***********9963 PP

  == domain 6  score: 3.3 bits;  conditional E-value: 0.047
                 HHHHHT-HHHHHHHHT CS
     VWA_3_C   2 LAaeSGnedtaklLrk 17 
                 LAae G+   +k+L k
  EEA21485.1 258 LAAENGHVVVVKMLLK 273
                 9*************87 PP

  == domain 7  score: 1.7 bits;  conditional E-value: 0.15
                 HHHHT-HHHHHHHHTTEEE.- CS
     VWA_3_C   3 AaeSGnedtaklLrkVVdvvD 23 
                 A++ G+e  +k+L k  +v +
  EEA21485.1 327 ASAAGQEVVVKILLKLNEV-N 346
                 8999***********9999.4 PP

  == domain 8  score: 9.6 bits;  conditional E-value: 0.00048
                 HHHHHT-HHHHHHHHT CS
     VWA_3_C   2 LAaeSGnedtaklLrk 17 
                 LAae G+e  +klL k
  EEA21485.1 360 LAAENGHETVVKLLLK 375
                 9*************76 PP

>> F-box_4  F-box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   7.7e-05      0.13       3      46 ..      27      71 ..      25      77 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 7.7e-05
     F-box_4  3 dsLssLPlevlqhiaslLDsfs.LsqLslvskllrevcssllqer 46
                 sL sLP e+l  +a++LD  s +  Ls+ +++l    s ll er
  EEA21485.1 27 MSLLSLPPELLAIVAQYLDADSdINALSQANRTLHSFHSYLLYER 71
                6899***************8774888*********9999999888 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   9.8e-05      0.16       1      35 [.      27      62 ..      27      63 .. 0.94

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 9.8e-05
                -HHHHS-HHHHHHHHHTS-HHH.HHHHCTT-HHHHH CS
       F-box  1 ftlsrLPsevlrhILerLplsd.llalrrVSkgwri 35
                ++l++LP+e+l  + ++L+  + + al++  +++++
  EEA21485.1 27 MSLLSLPPELLAIVAQYLDADSdINALSQANRTLHS 62
                799*************************99999886 PP

>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.1   9.4e-05      0.15       2      44 ..      30      71 ..      29      74 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 9.4e-05
  F-box-like  2 srLPdEiLlqIFsyLpps.dLlrlalVCrrWrrvaldtplLWrr 44
                ++LP+E+L  + +yL++  d+ +l++  r  +++  +  lL+ r
  EEA21485.1 30 LSLPPELLAIVAQYLDADsDINALSQANRTLHSFH-SY-LLYER 71
                79*************755499999*****999995.44.78876 PP

>> 3HCDH_RFF  3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       5.8   9.4e+03      10      23 ..     116     130 ..     112     135 .. 0.70
   2 ?    5.8   0.0     0.011        18       4      21 ..     148     166 ..     145     181 .. 0.77
   3 ?   -0.1   0.0      0.79   1.3e+03       5      22 ..     251     268 ..     250     273 .. 0.84
   4 ?   -3.4   0.0       8.5   1.4e+04       5      22 ..     319     336 ..     318     336 .. 0.77
   5 ?    0.1   0.0      0.67   1.1e+03       5      22 ..     353     370 ..     353     376 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 5.8
   3HCDH_RFF  10 tqraaeeg.rpvvlf 23 
                    aa+eg ++vv++
  EEA21485.1 116 LIWAAREGhEDVVML 130
                 556888898899987 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.011
   3HCDH_RFF   4 TdGrtAtqraaeeg.rpvv 21 
                 ++GrtA + aae+g ++vv
  EEA21485.1 148 SNGRTAISWAAENGyETVV 166
                 6899999999998855555 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.79
   3HCDH_RFF   5 dGrtAtqraaeegrpvvl 22 
                  Grt  ++aae+g+ vv+
  EEA21485.1 251 EGRTPLSLAAENGHVVVV 268
                 79*********8877775 PP

  == domain 4  score: -3.4 bits;  conditional E-value: 8.5
   3HCDH_RFF   5 dGrtAtqraaeegrpvvl 22 
                  Grt  + a + g++vv+
  EEA21485.1 319 HGRTPLSYASAAGQEVVV 336
                 588888888888888886 PP

  == domain 5  score: 0.1 bits;  conditional E-value: 0.67
   3HCDH_RFF   5 dGrtAtqraaeegrpvvl 22 
                 +Grt  ++aae+g+++v+
  EEA21485.1 353 NGRTPLSLAAENGHETVV 370
                 69***********66654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (445 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       312  (0.017402); expected 358.6 (0.02)
Passed bias filter:                      276  (0.0153941); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.41
# Mc/sec: 3233.69
//
Query:       EEA21486.1  [L=670]
Description: Exocyst complex component Exo84, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.2e-69  232.9   0.5    3.2e-69  232.9   0.5    2.2  3  Exo84_C         Exocyst component 84 C-terminal
    3.5e-18   65.5   1.4    3.5e-18   65.5   1.4    2.3  2  Vps51           Vps51/Vps67
  ------ inclusion threshold ------
       0.11   12.6   0.1         13    5.9   0.0    2.8  2  Exonuc_VII_S    Exonuclease VII small subunit
       0.21   11.7   1.4       0.54   10.3   0.3    2.1  2  COG2            COG (conserved oligomeric Golgi) complex comp
       0.29   11.8   8.7       0.82   10.3   5.2    2.7  2  HIP1_clath_bdg  Clathrin-binding domain of Huntingtin-interac
       0.31   10.6   5.8        1.9    8.0   1.9    2.4  2  Exonuc_VII_L    Exonuclease VII, large subunit
          1   10.0   5.7        6.3    7.5   2.3    2.8  2  BST2            Bone marrow stromal antigen 2
        2.1    7.9   5.5        1.2    8.7   2.9    1.9  2  HAUS6_N         HAUS augmin-like complex subunit 6 N-terminus


Domain annotation for each model (and alignments):
>> Exo84_C  Exocyst component 84 C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.7      0.53   1.2e+03      30      95 ..     132     198 ..     121     215 .. 0.60
   2 ?   -3.3   0.0       2.8   6.3e+03      47      71 ..     371     395 ..     350     403 .. 0.56
   3 !  232.9   0.5   1.4e-72   3.2e-69       1     204 [.     439     638 ..     439     639 .. 0.95

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.53
     Exo84_C  30 esklkklskklkdeeavlqdlislkveqrreelasklsrellsknevkklksnvslLi.rLgledkA 95 
                 e+++++++++l++ + +++  ++ +v q+r++ ++   +    k e+  l++ +s L+  Lg++++A
  EEA21486.1 132 EEEIRDYQQSLRRVKNRTSTDLQQNVYQNRTQFIKISEEAEKLKGEMRTLRTLMSELTtTLGQTHDA 198
                 4556666666665555556666666666666666333333334445555555565554245555555 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 2.8
     Exo84_C  47 lqdlislkveqrreelasklsrell 71 
                 l +  +  ve +r++l s++ ++ +
  EEA21486.1 371 LLATFRKTVEDLRKTLRSEIETSSR 395
                 2333444566666666666655554 PP

  == domain 3  score: 232.9 bits;  conditional E-value: 1.4e-72
     Exo84_C   1 rwvedlldeldieiarrkFeeAVdlleklesklkklskklkdeeavlqdlislkveqrreelasklsrellskne.vkklksnvslLirLgledkArel 98 
                 rwve ++deldi+ia ++FeeAV+++e    +l+kl+++lk + +++qd+i+ kv++r+++las lsr l++k++   ++k++v +L rLg+ed+Are+
  EEA21486.1 439 RWVEGQIDELDIDIALQHFEEAVSSVE----RLRKLARGLKGN-TFAQDVINQKVDERATNLASILSRALVDKHSfLVATKTHVGWLARLGFEDRAREA 532
                 7*************************7....7*********97.89************************976652778******************** PP

     Exo84_C  99 fLenrsnliqkrirqikfegdlslYitqlavvrFtlikntveefqecFkenkskmsSalvkWakeevdkfvkllerqllndek...lseecikiarkqa 194
                 +L +rs++i+kr+rq+ fegdl+lYi+q+++v+Ftl+knt++++q+cF++    m+Sa +kWake++d+f+++l rql++ ++   ++++c+++  +qa
  EEA21486.1 533 YLRARSEVIHKRARQCIFEGDLPLYIFQICFVYFTLVKNTISIYQQCFPP---MMTSASIKWAKEHLDQFNAILVRQLSSVQRgtkIWQKCMDTLDEQA 628
                 *************************************************9...7*************************9887555778********** PP

     Exo84_C 195 deLkevGLDf 204
                 + L+evG+Df
  EEA21486.1 629 ALLTEVGVDF 638
                 *********9 PP

>> Vps51  Vps51/Vps67
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.5   1.4   1.6e-21   3.5e-18       2      83 ..     113     194 ..     112     197 .. 0.96
   2 ?   -0.6   0.1      0.66   1.5e+03      22      38 ..     377     393 ..     364     396 .. 0.69

  Alignments for each domain:
  == domain 1  score: 65.5 bits;  conditional E-value: 1.6e-21
       Vps51   2 dspdfdaeayvrellakstlkellkveasllseiraldselkalVydnYskLisasdtIrkmksemdkldqklselkqaisk 83 
                 ++p+  +e+yv+ lla+++ +e++ +++sl++ + ++ ++l+++Vy+n +++i++s++ +k+k+em++l++ +sel+ ++++
  EEA21486.1 113 KDPSLPVEKYVAGLLANASEEEIRDYQQSLRRVKNRTSTDLQQNVYQNRTQFIKISEEAEKLKGEMRTLRTLMSELTTTLGQ 194
                 789999***********************************************************************99887 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.66
       Vps51  22 kellkveasllseiral 38 
                 k++  ++++l+sei++ 
  EEA21486.1 377 KTVEDLRKTLRSEIETS 393
                 67778888888888875 PP

>> Exonuc_VII_S  Exonuclease VII small subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0     0.035        79      18      41 ..     446     469 ..     444     470 .. 0.88
   2 ?    5.9   0.0    0.0058        13      26      45 ..     607     626 ..     600     629 .. 0.90

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.035
  Exonuc_VII_S  18 gelsLeeslklyeeGvkLlkeCek 41 
                   +el+++ +l+ +ee+v  +++++k
    EEA21486.1 446 DELDIDIALQHFEEAVSSVERLRK 469
                   699*************99988776 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0058
  Exonuc_VII_S  26 lklyeeGvkLlkeCekkLde 45 
                   l  +++G+k+ ++C++ Lde
    EEA21486.1 607 LSSVQRGTKIWQKCMDTLDE 626
                   5679**************97 PP

>> COG2  COG (conserved oligomeric Golgi) complex component, COG2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.3   0.00024      0.54      23      92 ..     130     199 ..     111     236 .. 0.76
   2 ?   -1.7   0.0       1.3   2.8e+03      79      96 ..     373     390 ..     363     403 .. 0.59

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00024
        COG2  23 rhgvpLeslrrdLeaylkllekellelvnedyadFvslSghLvglqeeleevesplaaarkkvesvrekl 92 
                  +  ++++ ++ L+   + ++++l + v ++   F+++S++   l+ e++++++ ++++++ + +++++ 
  EEA21486.1 130 ASEEEIRDYQQSLRRVKNRTSTDLQQNVYQNRTQFIKISEEAEKLKGEMRTLRTLMSELTTTLGQTHDAT 199
                 45678999*******************************9877777777777777777777776666654 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 1.3
        COG2  79 aaarkkvesvreklsere 96 
                 a++rk ve++r+ l   +
  EEA21486.1 373 ATFRKTVEDLRKTLRSEI 390
                 444555555554444433 PP

>> HIP1_clath_bdg  Clathrin-binding domain of Huntingtin-interacting protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   5.2   0.00036      0.82      19      81 ..     136     198 ..     132     210 .. 0.89
   2 ?    1.5   0.1      0.21   4.6e+02      58      92 ..     368     403 ..     348     408 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00036
  HIP1_clath_bdg  19 rqaqeeverekkeleeelerlkeeaerkleeqkeelekLkreleakraelarlkssLesseqs 81 
                     r  q+++ r+k++++++l++   +++ +  + +ee ekLk e+ + r+ +++l ++L +++ +
      EEA21486.1 136 RDYQQSLRRVKNRTSTDLQQNVYQNRTQFIKISEEAEKLKGEMRTLRTLMSELTTTLGQTHDA 198
                     778******************************************************876654 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.21
  HIP1_clath_bdg  58 krel.eakraelarlkssLesseqsgeqlssqlaaL 92 
                     k+el ++ r+ ++ l+++L+s+ +++++    l +L
      EEA21486.1 368 KNELlATFRKTVEDLRKTLRSEIETSSRTGDALRTL 403
                     666514568899999999999999998888888776 PP

>> Exonuc_VII_L  Exonuclease VII, large subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   1.9   0.00086       1.9     140     236 ..     133     215 ..     110     257 .. 0.47
   2 ?    3.6   0.1     0.018        40     127     268 ..     302     473 ..     298     502 .. 0.48

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00086
  Exonuc_VII_L 140 pdkaeleeqleelerrlekaikrlleekkqrleklasrlkspeellerkrqrldeleerleralkkqlkkkrerleelkerl.k.......ekleek 228
                   +++++++++l+++++r+++ +++++ ++++++ k++                     e+ e+ lk ++++ r+ ++el+++l +       ++l+++
    EEA21486.1 133 EEIRDYQQSLRRVKNRTSTDLQQNVYQNRTQFIKIS---------------------EEAEK-LKGEMRTLRTLMSELTTTLgQthdatgsNQLQAA 207
                   222333444444444444444444444444443333.....................33333.3333333333333333222222111111222222 PP

  Exonuc_VII_L 229 kerlkklk 236
                   ++r +k++
    EEA21486.1 208 DDRASKRS 215
                   22222222 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.018
  Exonuc_VII_L 127 rapTPta.aAelvvpdkael............eeqleelerrlekaikrlleekkqrleklasrlkspeellerkrqrldeleerleralkkq..lk 208
                   r p Pt+ +Ae  + + +++            +++ e+ +r + +ai+ ++ +++   +  +++ + ++ell++ r+ +++l++ l+++++++  + 
    EEA21486.1 302 RGPAPTKlVAEECW-QLQDIdmidlganlgpgAARAEAEHRGVAHAINIRVGSQSYTYRYDQRNNTAKNELLATFRKTVEDLRKTLRSEIETSsrTG 397
                   55666653344444.4444555566666666655556666666666666665555444433333345666777777777777777777555442322 PP

  Exonuc_VII_L 209 kkrerleelkerlk.................ekleekkerlkklkerlelleekkerleeleeklealsplkvLkrG 268
                    + ++l +l+ + k                  +++ k+++l+ ++ ++++  + + +l++ ee +++++ l+ L+rG
    EEA21486.1 398 DALRTLGQLEGHRKsgifdnpesfkdkpevrIDVDGKQQNLRWVEGQIDE-LDIDIALQHFEEAVSSVERLRKLARG 473
                   22223333332111233333322222222222222333333333333332.22334455555666666666666665 PP

>> BST2  Bone marrow stromal antigen 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   2.3    0.0028       6.3      43      86 ..     146     189 ..     127     194 .. 0.83
   2 ?    2.5   0.1     0.096   2.1e+02      37      61 ..     369     393 ..     353     411 .. 0.74

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0028
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        BST2  43 cnqtvvtLkasLekekaqsqkqqakvqelqgeikkLnqkLqdae 86 
                  n+t+ +L++   ++++q  k  +++++l+ge+++L   + +  
  EEA21486.1 146 KNRTSTDLQQNVYQNRTQFIKISEEAEKLKGEMRTLRTLMSELT 189
                 489********************************998776655 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.096
                 HHHHHHHHHHHHHHHHHHHHHHHHH CS
        BST2  37 eaqaatcnqtvvtLkasLekekaqs 61 
                 +   at  +tv++L++ L  e   s
  EEA21486.1 369 NELLATFRKTVEDLRKTLRSEIETS 393
                 4456999*********999875544 PP

>> HAUS6_N  HAUS augmin-like complex subunit 6 N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   2.9   0.00052       1.2     137     229 .]     134     228 ..     113     228 .. 0.69
   2 ?   -3.4   0.0       2.6   5.8e+03     118     165 ..     483     515 ..     467     546 .. 0.53

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00052
     HAUS6_N 137 aaskkaqdlsklvaahrvslrrflrekaaadrarqkyqenaqllekkerelraeleelqaelkae.....keaakkekkeasedaeeekikkvrnlWs 229
                  + + +q+l++++ +++  l++ + + +++     k++e+a+ l+ + r lr+ ++el+  l        +++ + ++++as+++++  + +++n+W+
  EEA21486.1 134 EIRDYQQSLRRVKNRTSTDLQQNVYQNRTQ---FIKISEEAEKLKGEMRTLRTLMSELTTTLGQThdatgSNQLQAADDRASKRSNRSSVANLENMWN 228
                 344455556666666666666665555555...5689999*****************99999866755554444444555555555559999999996 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 2.6
     HAUS6_N 118 Vlkkvlkekskklalevreaaskkaqdlsklvaahrvslrrflrekaa 165
                 V+ + + e+ +               +l  +  +  v ++ fl + ++
  EEA21486.1 483 VINQKVDERAT---------------NLASILSRALVDKHSFLVATKT 515
                 33333333333...............4555555555555555544444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (670 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1192  (0.0664845); expected 358.6 (0.02)
Passed bias filter:                      750  (0.0418317); expected 358.6 (0.02)
Passed Vit filter:                        74  (0.00412739); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.71u 0.28s 00:00:00.99 Elapsed: 00:00:00.44
# Mc/sec: 4608.37
//
Query:       EEA21487.1  [L=171]
Description: mitochondrial import receptor subunit (Tom20), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-46  157.7   0.8    1.7e-46  157.5   0.8    1.0  1  MAS20     MAS20 protein import receptor
  ------ inclusion threshold ------
      0.052   14.0   0.0      0.072   13.5   0.0    1.2  1  DUF4199   Protein of unknown function (DUF4199)
        0.1   13.3   0.0       0.17   12.6   0.0    1.4  1  PMC2NT    PMC2NT (NUC016) domain


Domain annotation for each model (and alignments):
>> MAS20  MAS20 protein import receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  157.5   0.8   2.9e-50   1.7e-46       2     128 ..      12     142 ..      11     143 .. 0.98

  Alignments for each domain:
  == domain 1  score: 157.5 bits;  conditional E-value: 2.9e-50
       MAS20   2 gvaaaaflgYcvYFDrkRrsdpefkkklrerrkkqakaakeeeeaekaekkk..kealeeakee.lptdaeevekfFleevqlGEellaq.geeeeaae 96 
                 g+++++fl+Y+v+FD+kR+sdpef+k l++++++ a+aakee+ea+ a++++  k+a+++akee +ptd ee+e++F+ +v++GE+l+a+ ++++eaa+
  EEA21487.1  12 GTVVTGFLAYAVWFDYKRQSDPEFRKALKRDNRRMARAAKEEAEAQGAAQREeiKKAVNAAKEEgFPTDLEEKEAYFMGQVAKGESLCAEgSDNVEAAL 110
                 899***********************************************999*99**********************************99******* PP

       MAS20  97 hlynAlkvcpqPqeLlqilqktlPeevfelll 128
                 ++y+Alkv+pqP++L++i++kt+P++v+e+l+
  EEA21487.1 111 AFYKALKVYPQPKDLISIYDKTVPKDVLEVLA 142
                 *****************************997 PP

>> DUF4199  Protein of unknown function (DUF4199)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   1.2e-05     0.072      77     139 ..      13      73 ..       5      93 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 1.2e-05
     DUF4199  77 slvagllsavfqyiyfnfidpdfienyiaeilekleeakeesaeeenaemseeeikealesls 139
                 ++v+g+l  ++++ y +  dp+f + ++     ++ +akee+  e++ ++++eeik+a+++ +
  EEA21487.1  13 TVVTGFLAYAVWFDYKRQSDPEFRKALKRDNRRMARAAKEEA--EAQGAAQREEIKKAVNAAK 73 
                 5789************************99987776665544..5688899****99998655 PP

>> PMC2NT  PMC2NT (NUC016) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   2.8e-05      0.17      15      55 ..      25      65 ..      13      89 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 2.8e-05
      PMC2NT 15 ldfyrsldpefaksldeqserllslinsllklaaskseisa 55
                +d+ r  dpef+k+l+++++r+ + +++ ++++++ ++ + 
  EEA21487.1 25 FDYKRQSDPEFRKALKRDNRRMARAAKEEAEAQGAAQREEI 65
                89**********************99998666665555433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (171 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1145  (0.063863); expected 358.6 (0.02)
Passed bias filter:                      696  (0.0388198); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 1211.78
//
Query:       EEA21488.1  [L=263]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
       0.28   10.5   1.3        3.5    6.9   0.2    2.2  2  Sarcoglycan_1    Sarcoglycan complex subunit protein
        3.9    7.1   7.7          7    6.3   6.8    1.8  1  Tetraspanin      Tetraspanin family
        4.4    6.5   9.1        2.2    7.5   7.0    1.6  1  ABC2_membrane_2  ABC-2 family transporter protein
        4.6    7.7   9.9       0.46   10.9   2.2    3.0  3  FeoB_associated  FeoB-associated Cys-rich membrane protein


Domain annotation for each model (and alignments):
>> Sarcoglycan_1  Sarcoglycan complex subunit protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.2   0.00077       3.5       8      52 ..       3      47 ..       2      65 .. 0.89
   2 ?    2.7   0.1     0.015        66       5      39 ..     104     138 ..     102     199 .. 0.74

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.00077
  Sarcoglycan_1  8 rkrclyllvllLlllaivnLaltiwilkvLrissnGmgsleiipd 52
                   rk +ly+   +Ll++a v Lal   ++ +L i++  +g  +i ++
     EEA21488.1  3 RKKFLYIPFTILLITATVQLALVSRMVAFLHIQKTEIGTYHILSN 47
                   788999999************************999998877766 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.015
  Sarcoglycan_1   5 rgrrkrclyllvllLlllaivnLaltiwilkvLri 39 
                    + r k +l++l +   ll++ nLa  + +  v  +
     EEA21488.1 104 QQRHKSILLTLTIAVSLLVLFNLAALVYVFAVTYL 138
                    5788999999*************988777666444 PP

>> Tetraspanin  Tetraspanin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   6.8    0.0016         7      45     106 ..      72     138 ..      14     156 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0016
                  ........XXXXXXXXXXXXXXXXXXXXXXXX.....XXXXXXXXXXXXXXXXXXXXXXXXX--HHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Tetraspanin  45 dpailaillivvGvllfllgflGcigalkenk.....cllltfsllllvlfllelaagilgfvfsdk 106
                  ++ +++++    Gv++ + +++ c+  +++ +      +llt  + + +l+l+ laa +++f+++  
   EEA21488.1  72 NQGHVTNGAAGYGVVISIASLVACVFLRRDTYqqrhkSILLTLTIAVSLLVLFNLAALVYVFAVTYL 138
                  555677888899**************99998888888999999999999999999999999988766 PP

>> ABC2_membrane_2  ABC-2 family transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   7.0   0.00049       2.2     178     283 ..     112     213 ..      79     218 .. 0.78

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.00049
  ABC2_membrane_2 178 lalglllSsvarssreaaalalglfvvlailvpivlygvaellagpavpqeindflsllsptsayntllneilagsdlnalgstatnllillll 271
                      l+l++++S ++  ++ aa+++++ + +l i  +i   g+a + a + +   +   ++  +p  +y++ll  +l++s  ++l ++a  +++  ++
       EEA21488.1 112 LTLTIAVSLLVL-FNLAALVYVFAVTYLTIENKINI-GIARAAASAGP--GVGYSIDSWTPETWYQALLLLPLESSTHSTLSAAAQEMVAWRVW 201
                      566777777776.67777777666666666555544.55555554444..999***********************9999************** PP

  ABC2_membrane_2 272 lavllvlgyvlF 283
                      ++ + ++g+v+ 
       EEA21488.1 202 IILYQIVGAVVV 213
                      *******99876 PP

>> FeoB_associated  FeoB-associated Cys-rich membrane protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0      0.48   2.1e+03       5      17 ..      87      99 ..      84     109 .. 0.48
   2 ?   -0.8   0.5      0.48   2.1e+03       9      13 ..     128     132 ..     112     143 .. 0.53
   3 ?   10.9   2.2    0.0001      0.46       4      37 ..     207     233 ..     201     239 .. 0.85

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.48
  FeoB_associated  5 Vgliiaaavafvi 17
                     + ++ ++a++f+ 
       EEA21488.1 87 ISIASLVACVFLR 99
                     3333334444443 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.48
  FeoB_associated   9 iaaav 13 
                       +++v
       EEA21488.1 128 ALVYV 132
                      12333 PP

  == domain 3  score: 10.9 bits;  conditional E-value: 0.0001
  FeoB_associated   4 IVgliiaaavafvirrlikkkkkGsCgggCsgCs 37 
                      IVg+++++ ++++  r +k+     Cg  C gC+
       EEA21488.1 207 IVGAVVVGWMGMAYLREWKR----VCG--C-GCG 233
                      9************9999999....899..6.665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (263 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1130  (0.0630264); expected 358.6 (0.02)
Passed bias filter:                      517  (0.028836); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 1827.27
//
Query:       EEA21489.1  [L=573]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-32  113.2  58.9    2.8e-32  112.0  56.7    2.6  2  MFS_1     Major Facilitator Superfamily
      4e-21   75.1  25.8    6.5e-21   74.4  25.8    1.2  1  TRI12     Fungal trichothecene efflux pump (TRI12)
    1.2e-15   57.4   6.2    1.2e-15   57.4   6.2    2.4  3  Sugar_tr  Sugar (and other) transporter
  ------ inclusion threshold ------
      0.058   13.8   1.3       0.11   12.9   0.1    2.2  2  DUF3796   Protein of unknown function (DUF3796)
       0.27   11.5   5.2       0.11   12.7   0.9    2.6  2  DUF3522   Protein of unknown function (DUF3522)
        1.3    8.9   5.3        5.3    7.0   5.3    2.0  1  PIG-P     PIG-P
        2.8    6.1  13.2          3    6.0   9.9    2.5  2  OATP      Organic Anion Transporter Polypeptide (OATP) family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.0  56.7   1.1e-35   2.8e-32       2     352 ..      73     472 ..      72     473 .. 0.87
   2 ?   -2.6   0.0      0.78     2e+03     152     232 ..     537     554 ..     518     567 .. 0.55

  Alignments for each domain:
  == domain 1  score: 112.0 bits;  conditional E-value: 1.1e-35
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgag 100
                 + a+f+  l++++lg+alp ++a +l+ +  +  ++   y+l  +v++++++++sd fGr+++l +++++fa+g++++++a ++ +++v+rvlqG+g+g
  EEA21489.1  73 AAAVFVFQLDATCLGIALP-TIAGELNGQTLQSFWANMSYYLCGLVMQPLWASISDTFGRKPLLYICMAFFAVGSIIFALAKNMNMIIVGRVLQGFGGG 170
                 6799***************.*******888888889999***********************************77777779999************** PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee........... 188
                 ++  ++ +++ad+++ +er++++gl+++ +++G ilgp +g+l++++++Wr++ +++ +++ +a+ l +++l+ +p++   + +k +            
  EEA21489.1 171 GIDVLAEIILADMTTLQERSLYLGLMAIPMAIGNILGPSIGALFSTYASWRWIGWFNLPFLGFALPLLIFFLRLRPVQLDESFTKNLNrldwigmifli 269
                 ****************************************************************888778888888877777776666999******** PP

       MFS_1 189 .........................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsgllla 246
                                                          + +   p++p  +++ ++  + + l+++++ ++++ +ll +lpl l +  gl    ++
  EEA21489.1 270 lattifvipfswagslypwrswqtllpmmlgvalliiftiyEAKPAVPVIP-HRLFYSKT-FNMSLAGSFIHGMILVSLLNYLPL-LYQSVGLE--TST 363
                 **************9999999999999998888888888877777777777.55555555.438*********************.5*******..555 PP

       MFS_1 247 glllallalvgailallagrlsdr...lgrrrrlllallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfn 342
                 g +++ll +v+  +a+ ag +++     g  + + ++ +++++++ +lal+++  s+++ + + +l+G+g++  + +ll + +++   + +g a++  +
  EEA21489.1 364 GSAVSLLPAVITSVAVSAGLMMTVgavGGYIWLIRVSWVAVTVGSGLLALFNLGPSSSMRISLPILWGIGVAGLRLLLLPMQASVKNIDDTGLAIAQQQ 462
                 5555555555555666666666554433449999***********************************999997777776666666699999999999 PP

       MFS_1 343 tagslggalg 352
                  ++ +gg++g
  EEA21489.1 463 AFRMFGGLVG 472
                 9999999988 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 0.78
       MFS_1 152 avfyilaivsllafvlfllllpeepperkrkspkeeekgtgpaplvpawkallkdpvlwillialllfffgfsglltllpl 232
                  +fy + +++ l+                                                                 + l
  EEA21489.1 537 TLFYTMVGFGGLG---------------------------------------------------------------LITSL 554
                 3333333333333...............................................................33322 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.4  25.8   2.6e-24   6.5e-21      51     558 ..      70     561 ..      47     568 .. 0.80

  Alignments for each domain:
  == domain 1  score: 74.4 bits;  conditional E-value: 2.6e-24
       TRI12  51 lnvvatyfvlqasasalpnilqdvgqsensslfstlw.ttgqavsilvm....grltdrfgrrpfvilthilglvgaivgctatkfntllaamtllgva 144
                 + ++a+ fv+q  a++l   l  +    n   + ++w  +   +  lvm      ++d fgr+p++ +   +  vg+i+ + a+++n ++    l g  
  EEA21489.1  70 IGLAAAVFVFQLDATCLGIALPTIAGELNGQTLQSFWaNMSYYLCGLVMqplwASISDTFGRKPLLYICMAFFAVGSIIFALAKNMNMIIVGRVLQGFG 168
                 4567999*******9999999988766666555566625777888888822224679*****************************************9 PP

       TRI12 145 agpaga.splfvgelmsnktkflgllivsipvvvtsglspylgqrlaiqgswrwifyiyiitsaiavllivvwyyppsfaqlhgkkvrkreelakldwi 242
                  g     + +++ ++ + + + l l +++ip+ + + l+p +g  ++   swrwi +  +     a+ l++ +       ql     +  ++l +ldwi
  EEA21489.1 169 GGGIDVlAEIILADMTTLQERSLYLGLMAIPMAIGNILGPSIGALFSTYASWRWIGWFNLPFLGFALPLLIFFLR-LRPVQLDE---SFTKNLNRLDWI 263
                 988765266777888777777777778899*************************99999999999888766544.34456654...4456899***** PP

       TRI12 243 giilvivgvslfllgvswggkpnspwnsakviglissglgslvvfalyevygkpvrpivppalfkdtrgfvcillissimgamnlslviiyp..qqvvn 339
                 g+i++i  +++f++  sw g    pw s + +  +  g+  l++f++ye   kp  p++p  lf  ++ f   l  s i g + +sl    p   q v 
  EEA21489.1 264 GMIFLILATTIFVIPFSWAGSL-YPWRSWQTLLPMMLGVALLIIFTIYE--AKPAVPVIPHRLFY-SKTFNMSLAGSFIHGMILVSLLNYLPllYQSVG 358
                 ********************75.7********99***************..5************7.578888888888888888777655552224444 PP

       TRI12 340 i..fgsslknweetawmsatasfgtgagvvvlgslfhlvrhirwqilvgalwltaf.lgamssvnrdnknaaialsvlsgfvvawaqditmllvqfitt 435
                 +     s      +   s + s g +  v  +g  + l+r     + vg+  l+ f lg  ss+        i+l +l g+ va  + + + +   +  
  EEA21489.1 359 LetSTGSAVSLLPAVITSVAVSAGLMMTVGAVGGYIWLIRVSWVAVTVGSGLLALFnLGPSSSM-------RISLPILWGIGVAGLRLLLLPMQASVKN 450
                 3003334444445555566667777777777888888888766678888888887745665554.......599**********999998889999999 PP

       TRI12 436 dedlgvafavvaaarpfagsiftaafislysnrypkelashlssalrgtdipqasfsslleaaksgrieavkalpgmt.teiaavvsramadsytasya 533
                  +d g+a+a   a r f g +  +   +++        +s +s+++   ++p + +++l +a      +a+  +p +    +++ v + + + y   + 
  EEA21489.1 451 IDDTGLAIAQQQAFRMFGGLVGLTIGSTIF--------NSVFSASISSIELPAGPLTALANAN-----DAIAFIPELRlLGVSSEVLNPILEIYLKCFR 536
                 9**************998876544433343........345566677789******9998876.....6777777775246889999999********* PP

       TRI12 534 nvyyfamalgvipiiaslcmrdldr 558
                  ++y  + +g + +i+sl m+dld 
  EEA21489.1 537 TLFYTMVGFGGLGLITSLIMKDLDL 561
                 ***********************96 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.4   6.2   4.7e-19   1.2e-15      45     187 ..     101     242 ..      46     252 .. 0.82
   2 ?   -2.8   3.2      0.84   2.1e+03     272     307 ..     345     382 ..     326     419 .. 0.75
   3 ?   -5.6   7.1       5.8   1.5e+04      60     125 ..     378     444 ..     348     486 .. 0.69

  Alignments for each domain:
  == domain 1  score: 57.4 bits;  conditional E-value: 4.7e-19
                 ..HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHH CS
    Sugar_tr  45 svlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvsly 143
                 +++s +   ++++ +++ + +   ++d+fGRk+ l i+ ++f +g+++ a+ak   ++ ++ivgRvl G+g G++ vl+ + ++ +++ + R+   +l 
  EEA21489.1 101 TLQSFWANMSYYLCGLVMQPLWASISDTFGRKPLLYICMAFFAVGSIIFALAK---NMNMIIVGRVLQGFGGGGIDVLAEIILADMTTLQERSLYLGLM 196
                 5555555556666666666666679****************************...9****************************************** PP

                 HHHHHHHHHHHHHHHHHHHTSS-TTHHHHHH...HCCHHHHHHHHHH CS
    Sugar_tr 144 qlaitfGilvaaifglglnktsnadgwrill...glqlvpallllil 187
                    +++G +++  +g+ ++++ + ++w   +   +l ++++ll+++l
  EEA21489.1 197 AIPMAIGNILGPSIGALFSTYAS-WRWIGWFnlpFLGFALPLLIFFL 242
                 ***********************.44444440003344444333333 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.84
                 HHHHHTTTHHHHSS-THH..HHHHHHHHHHHHHHHHHH CS
    Sugar_tr 272 aimyysptifenlglsks..llvtiivgvvnfvatfva 307
                 ++++y p +++++gl++s   +v+++  v++ va+ ++
  EEA21489.1 345 SLLNYLPLLYQSVGLETStgSAVSLLPAVITSVAVSAG 382
                 67889999999999999966555555555555555544 PP

  == domain 3  score: -5.6 bits;  conditional E-value: 5.8
                 HHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHH.HHHHHHHHH CS
    Sugar_tr  60 iiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigv.GlasvlvPm 125
                 ++++ +++++g + G+ + + ++ v + +g+ l a+ + + s  + i   +l Gigv Gl   l Pm
  EEA21489.1 378 AVSAGLMMTVGAVGGYIWLIRVSWVAVTVGSGLLALFNLGPSSSMRISLPILWGIGVaGLRLLLLPM 444
                 3444455667888888888888888888888888888888888888888888888873445555565 PP

>> DUF3796  Protein of unknown function (DUF3796)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.1       4.6   1.2e+04      27      35 ..     133     143 ..     123     158 .. 0.58
   2 ?   12.9   0.1   4.5e-05      0.11      26      78 ..     226     277 ..     210     310 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 4.6
     DUF3796  27 lllffa..Ffa 35 
                 +ll+++  Ffa
  EEA21489.1 133 PLLYICmaFFA 143
                 44444411443 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 4.5e-05
     DUF3796  26 alllffaFfaffsfffvaklstvllDErfeenvkraaaiafkvaileiiiavl 78 
                 + l f++F+  +  ff+ +l+ v+lDE f++n +r   i+  + il+++i+v+
  EEA21489.1 226 FNLPFLGFALPLLIFFL-RLRPVQLDESFTKNLNRLDWIGMIFLILATTIFVI 277
                 56779999988888865.88****************************99986 PP

>> DUF3522  Protein of unknown function (DUF3522)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.1       2.2   5.6e+03     159     171 ..     138     150 ..     100     167 .. 0.59
   2 ?   12.7   0.9   4.5e-05      0.11      96     142 ..     275     321 ..     267     349 .. 0.70

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 2.2
     DUF3522 159 gllllalAlfllg 171
                 ++ ++a++ ++++
  EEA21489.1 138 CMAFFAVGSIIFA 150
                 2222222223333 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 4.5e-05
     DUF3522  96 glllvailqekdrwslantiipilvgllillvswliecvkkrklyps 142
                 +++ +  +  + +w++++t++p+++g+++l+++ ++e +    ++p+
  EEA21489.1 275 FVIPFSWAGSLYPWRSWQTLLPMMLGVALLIIFTIYEAKPAVPVIPH 321
                 555555556678**********************9999988888887 PP

>> PIG-P  PIG-P
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   5.3    0.0021       5.3      23      65 ..     274     312 ..     262     317 .. 0.77

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0021
       PIG-P  23 wallPeevlhalgityypnryWalavpayllmlvlyiyvalas 65 
                   ++P ++  +l    yp r W  ++p++l +++l+i++++ +
  EEA21489.1 274 IFVIPFSWAGSL----YPWRSWQTLLPMMLGVALLIIFTIYEA 312
                 445555555555....***********************9975 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   9.9    0.0012         3     132     225 ..     155     236 ..     142     282 .. 0.72
   2 ?   -1.2   0.0      0.19   4.8e+02     166     194 ..     454     482 ..     448     494 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.0012
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 132 vllfflaqlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllklyvdidseisltpkdprWvgaWWlgflilgvl 225
                 + +++++ +l+G+G+  i  l+   + D ++ ++ +lylg++    ++G +lG  +G+l+  +y  +           rW+g + l fl +++ 
  EEA21489.1 155 MNMIIVGRVLQGFGGGGIDVLAEIILADMTTLQERSLYLGLMAIPMAIGNILGPSIGALFS-TYASW-----------RWIGWFNLPFLGFALP 236
                 4489*****************************************************9765.58888...........5555333333222222 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.19
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 166 splylgilyalrilGpalGfllGslllkl 194
                 + l ++  +a+r++G  +G ++Gs + + 
  EEA21489.1 454 TGLAIAQQQAFRMFGGLVGLTIGSTIFNS 482
                 67788889999**********99987764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (573 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       609  (0.0339673); expected 358.6 (0.02)
Passed bias filter:                      229  (0.0127726); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.66u 0.32s 00:00:00.98 Elapsed: 00:00:00.47
# Mc/sec: 3633.24
//
Query:       EEA21490.1  [L=432]
Description: LysR family regulatory protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.7e-08   32.9   0.0    1.5e-07   30.4   0.0    2.0  2  Transferase  Transferase family


Domain annotation for each model (and alignments):
>> Transferase  Transferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0      0.04   7.2e+02      47      66 ..      41      60 ..      34      61 .. 0.80
   2 !   30.4   0.0   8.5e-12   1.5e-07     131     381 ..      83     354 ..      73     363 .. 0.71

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.04
  Transferase 47 elsqenvsekLktsLsetLt 66
                  +++   s+kL+ +Ls++L 
   EEA21490.1 41 RFDDVLDSDKLRRALSRLLE 60
                 567777899********995 PP

  == domain 2  score: 30.4 bits;  conditional E-value: 8.5e-12
  Transferase 131 ipllavqvTkfkcGgvalgvsvsHaiaDgaSlktfieswaelarge...kkvtvtplfarelllprpeppsv..............efdqlelrkfsa 211
                   p l++ +  f++    + +++ H+ +D+++l  +++ w ++ rg+   +++ v ++++    l +  pp++                       f+ 
   EEA21490.1  83 SPQLSICIITFQDA-TLVTITFLHTLMDIMGLYSILQGWSAVLRGQedeVPPFVGFDYDPLAGLTKTTPPQPyvfadklligarrlI--------FAL 171
                  57788888889988.899***************************933344444445555444555677777645544444333333........444 PP

  Transferase 212 settevkevvtkkivleklsaskleeLkkkasdesngk......pa.trfesvtallWrcavkarkldesketvlgiavdiRsrlepklpeeyfG... 299
                  + + e++ + +++  +  l a++l+ ++  a +e  ++      p  ++ +++ a+  + + +a kl +    +++ + d+R  l +     ++G   
   EEA21490.1 172 HYIFELFWYRQEEERVIFLPAKHLQRMRDSAMGELASQnisnekPFvSESDVLLAWWTQVVLRALKLAPRRMITIRNVFDCRPILTELGHIPSTGgtl 269
                  44444443333222222244555555555555444444222222224********9889999***********************9887776666222 PP

  Transferase 300 ..Nallsvvvkstakellseelsrivekvkeavkkaitkeylsseidweenstlkaelvskgkkdg..eevtvsswlklplyevdF 381
                     a +s +++  a+ +l+ +ls++++ + ++++++ ++e l+  ++ ++  tl  e  + ++ d    +++ s w k  l +vdF
   EEA21490.1 270 vaHAAFSTFTFLSARHILEMPLSFVASRIRKSLEHQRNQEQLQALLAIQKA-TLDNEHHPTLFGDPsmFHFMCSNWGKARLFQVDF 354
                  22466788888999*********************8888988888888888.7888888877777433568889999********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (432 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       339  (0.0189079); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 3018.23
//
Query:       EEA21491.1  [L=1088]
Description: hypothetical protein PMAA_053000 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.7e-11   42.9   0.0    9.3e-11   41.9   0.0    1.5  1  NACHT         NACHT domain
    4.2e-10   39.9   0.2    1.9e-09   37.8   0.2    2.2  1  HEAT_2        HEAT repeats
    3.7e-08   34.0   0.0    1.2e-07   32.3   0.0    1.9  1  NLRC4_HD2     NLRC4 helical domain HD2
    3.5e-07   29.9   0.0      0.055   13.7   0.0    3.3  2  HEAT          HEAT repeat
    3.1e-06   26.6   0.0    5.8e-06   25.7   0.0    1.4  1  NB-ARC        NB-ARC domain
     0.0011   19.4   0.9      0.012   16.1   0.6    3.0  2  HEAT_EZ       HEAT-like repeat
     0.0061   15.8   0.0      0.012   14.9   0.0    1.5  1  PNP_UDP_1     Phosphorylase superfamily
     0.0063   16.8   0.1      0.022   15.0   0.0    1.9  1  AAA_22        AAA domain
  ------ inclusion threshold ------
      0.016   15.9   0.5        7.8    7.5   0.1    3.3  2  HEAT_PBS      PBS lyase HEAT-like repeat
       0.02   15.3   0.0       0.08   13.3   0.0    2.1  2  AAA_16        AAA ATPase domain
      0.022   15.2   0.0      0.068   13.6   0.0    1.8  2  AAA           ATPase family associated with various cellular 
      0.047   14.0   0.7        1.8    9.0   0.2    2.8  2  Cohesin_HEAT  HEAT repeat associated with sister chromatid co
      0.054   14.0   0.0       0.43   11.1   0.0    2.4  2  AAA_18        AAA domain
      0.064   13.2   0.0       0.11   12.3   0.0    1.4  1  NTPase_1      NTPase
       0.16   11.7   0.0       0.29   10.8   0.0    1.4  1  AAA_24        AAA domain


Domain annotation for each model (and alignments):
>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.9   0.0   7.8e-14   9.3e-11       1     161 [.     394     549 ..     394     554 .. 0.75

  Alignments for each domain:
  == domain 1  score: 41.9 bits;  conditional E-value: 7.8e-14
                 SCEEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-...-HCHHHCCCCTS--SSS-C....CHHHHC.CSCCCEEEEEE-STT-S CS
       NACHT   1 rlvilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgnarsladllfsqlpepaapvse....vwavll.elperlLlilDglDelv 94 
                 r ++++G+aG+GKTtL +k++ +    +  ++ f+ +++++lr+l+  +    l+++ + ++ + +a+ +      ++  l +  +++L +lDglDe++
  EEA21491.1 394 RRILIRGRAGVGKTTLCKKIVYDFLYHQMWADLFDRIIWIPLRRLKGMS---DLDEFFRHEFFKHEAERDGlvikLRKTALdQAHTKTLWLLDGLDEVS 489
                 679****************************9***************98...5566666666666666655333344444404456778********** PP

                 S-TCH.........HHHHHCTTTTT--EEEEEEECCCHHHHCTTSSCE..EEEE--TCCHHHHHHHH CS
       NACHT  95 tdlgqkekqpvrtlLselirkkllpeasllltvrpralrdleeqleeaivlevegfsesrrkqlvrk 161
                    ++     +   L+e+++  ll e  +++t+rp a++ l+ +  +   le  gf  +++ +++ k
  EEA21491.1 490 GYRNP-----SGADLTEIFNS-LLNEDNVIITSRPHAVKLLGLTPFD-LELETVGFHVNQVYAYLAK 549
                 85555.....77789999998.9999************544433333.3666666666666666655 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.8   0.2   1.6e-12   1.9e-09      15      88 .]     885     962 ..     870     993 .. 0.71

  Alignments for each domain:
  == domain 1  score: 37.8 bits;  conditional E-value: 1.6e-12
      HEAT_2  15 evrraairaLgrignp..ealpaLvellededpavRraaaeaLgaig..dpealpaLkellddddddvvReaAaeaLa 88 
                   r++++raL+r  +    ++ ++ +++ d+ p+vRraa++aLg     +p+ l+a  ++l +d+d +vR+aA+e L+
  EEA21491.1 885 SCRKKILRALARRWHMsfNLIGIVANFMGDSYPDVRRAAIKALGTRSpwSPDILKAVIRRLENDEDLDVRRAAIEVLG 962
                 567777777774333224667777777777777777777777776663457777777777777777777777777664 PP

>> NLRC4_HD2  NLRC4 helical domain HD2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.3   0.0     1e-10   1.2e-07       1      85 [.     713     795 ..     713     827 .. 0.78

  Alignments for each domain:
  == domain 1  score: 32.3 bits;  conditional E-value: 1e-10
   NLRC4_HD2   1 HlsiQeFlAAlyvvlseeeeksevlkeflelekket.k.ellsls.kkaldkalksknghldlflrFLfGLlsesnqrlleellgqtk 85 
                 Hl++QeF+AA y+v++ + e++e+l  ++  + +e+ k e      +k l++   + +g++d+f rF+ GLl +  ++++ ++l++ +
  EEA21491.1 713 HLTFQEFFAAQYFVRCWRAESREPLIYLKPGHARENcKvE---IPpEKFLREE--KYSGRYDVFWRFVTGLLYSIDKQQVCSFLEKIE 795
                 ***********************99777777776654322...2224444444..46899*************999999988888433 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.7   0.0   4.6e-05     0.055       3      26 ..     906     929 ..     904     929 .. 0.86
   2 !   12.6   0.0   0.00011      0.13       1      25 [.     937     962 ..     937     963 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 4.6e-05
                 HHHHHHHT-SSHHHHHHHHHHHHH CS
        HEAT   3 PlllkllsDpspeVReaAakaLga 26 
                  ++ + + D+ p+VR+aA+kaLg+
  EEA21491.1 906 GIVANFMGDSYPDVRRAAIKALGT 929
                 5677789***************95 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 0.00011
                 HHHHHHHHH.T-SSHHHHHHHHHHHH CS
        HEAT   1 llPlllkll.sDpspeVReaAakaLg 25 
                 +l ++++ l +D++ +VR+aA++ Lg
  EEA21491.1 937 ILKAVIRRLeNDEDLDVRRAAIEVLG 962
                 6778889999***************9 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.7   0.0   4.9e-09   5.8e-06      11      87 ..     384     463 ..     381     526 .. 0.71

  Alignments for each domain:
  == domain 1  score: 25.7 bits;  conditional E-value: 4.9e-09
                 HHHCTTTSCSEEEEEEESTTSSHHHHHHHHCCSH...CCCCCCBTEEEEEEEESXXHHHHHHHXXHHHHHCCCTTSSSS- CS
      NB-ARC  11 kLlekdelqslvvalvGmgGvGKttlakqilnks...devegrFdsvawvvvsktdkseeiletilkeLslseddleeke 87 
                 kLl   + q   + + G++GvGKttl k+i+ ++   ++    Fd+++w+ + +    +++ e+  +e+ ++e++++   
  EEA21491.1 384 KLLDGRNAQPRRILIRGRAGVGKTTLCKKIVYDFlyhQMWADLFDRIIWIPLRRLKGMSDLDEFFRHEFFKHEAERDGLV 463
                 56667777777899****************9995333777789*******999999999999999999888766665444 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       4.9   5.9e+03      25      41 ..     539     555 ..     536     556 .. 0.89
   2 !   16.1   0.6     1e-05     0.012       1      53 [.     917     962 ..     917     963 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 4.9
     HEAT_EZ  25 lvpeilpaLlalLndds 41 
                 +v ++ ++L+++++d++
  EEA21491.1 539 HVNQVYAYLAKAMTDPD 555
                 578999*******9986 PP

  == domain 2  score: 16.1 bits;  conditional E-value: 1e-05
     HEAT_EZ   1 wrvRraAawaLGrlaggepellqplvpeilpaLlalLnddsd.eVRaaAagaLg 53 
                 + vRraA+ aLG        + +p  p+il+a +++L++d+d +VR aA+  Lg
  EEA21491.1 917 PDVRRAAIKALG--------TRSPWSPDILKAVIRRLENDEDlDVRRAAIEVLG 962
                 579********9........6678889**********999999******99998 PP

>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   9.7e-06     0.012     113     203 ..     166     266 ..      87     291 .. 0.64

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 9.7e-06
                 TCCCCTTSSEE--HHHHHHHHH....CHHTTT...............TTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHTT--EE CS
   PNP_UDP_1 113 gqyfpdsydapadpelrallke....aaealg...............ikvhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArelgipfa 192
                 ++++ +++d+ + +++++++ +    +                    + +h+G++a+++++  ++e ++rl  + g+ + eME+a +       ++p +
  EEA21491.1 166 FPPPEQVTDFLFESSYHHAAGKrtceE----CdkerlvkrkpretrtPYIHYGLIASGNQVMKDSETRDRLALQHGILCFEMEAAGLID-----ELPTL 255
                 445555555555555555555543331....2444555666677778************************************998765.....67777 PP

                 EEEEEEETTTB CS
   PNP_UDP_1 193 airvvsdlaag 203
                 +ir++ d+ + 
  EEA21491.1 256 VIRGICDYCDS 266
                 77777774444 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   1.8e-05     0.022       8     123 ..     396     512 ..     390     527 .. 0.69

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.8e-05
      AAA_22   8 lvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelkaerlsseellealeqalrarav.ielliiDEaqhlr. 104
                 +++ G +G+GKTtl++++++ +  ++  ++  ++++ + l  +++ +dl + + +++   ++a   +++ l+ +l++ + ++a  + l ++D  + ++ 
  EEA21491.1 396 ILIRGRAGVGKTTLCKKIVYDFLYHQMWADLFDRIIWIPLRRLKGMSDLDEFFRHEFFK-HEA---ERDGLVIKLRKTALDQAHtKTLWLLDGLDEVSg 490
                 7899*****************97665555588888888888888888888888888774.333...556666444444444444477899999999966 PP

      AAA_22 105 .s...eealeeL.rsllnlsrkgv 123
                  +    + l+e+  slln  +++v
  EEA21491.1 491 yRnpsGADLTEIfNSLLN--EDNV 512
                 614454444444366677..5554 PP

>> HEAT_PBS  PBS lyase HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   0.1    0.0066       7.8       1      11 [.     919     929 ..     919     945 .. 0.83
   2 ?    4.9   0.0     0.045        54       1      19 [.     953     973 ..     953     976 .. 0.75

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0066
                 HHHHHHHHHHH CS
    HEAT_PBS   1 vRraAakaLgq 11 
                 vRraA+kaLg+
  EEA21491.1 919 VRRAAIKALGT 929
                 9*********8 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.045
                 HHHHHHHHHHHCTS..GGGHH CS
    HEAT_PBS   1 vRraAakaLgqlgd..eeaip 19 
                 vRraA++ Lg+  +  +++++
  EEA21491.1 953 VRRAAIEVLGTQSSwsPDILE 973
                 9*********98885544444 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   6.7e-05      0.08      19      45 ..     388     414 ..     376     510 .. 0.80
   2 ?   -3.1   0.0       7.4   8.8e+03      71      88 ..     932     948 ..     868     993 .. 0.59

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 6.7e-05
      AAA_16  19 vrsgrpelvllsGesGvGKsslvrell 45 
                  r  +p+ +l++G +GvGK++l +++ 
  EEA21491.1 388 GRNAQPRRILIRGRAGVGKTTLCKKIV 414
                 45567899**************98775 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 7.4
      AAA_16  71 alaqalareellrqllde 88 
                 ++   + +  ++r l+++
  EEA21491.1 932 PWSPDILK-AVIRRLEND 948
                 33333323.444444444 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       6.5   7.8e+03      31      56 ..     133     158 ..     127     162 .. 0.76
   2 ?   13.6   0.0   5.7e-05     0.068       1      92 [.     396     509 ..     396     527 .. 0.73

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 6.5
                 TTTCSSSSTTHHHHHHHHHHHHHHHT CS
         AAA  31 gsellskyvgesekkirelfkeakek 56 
                  s+l  k v  +e++++++++ea + 
  EEA21491.1 133 ISQLEAKGVTRTEDDLKKIMEEALKR 158
                 56777888999999999999998555 PP

  == domain 2  score: 13.6 bits;  conditional E-value: 5.7e-05
                 EEEESSTTSSHHHHHHHHHHHH..........T....HEEEEEETTTCSSS........STTHHHHHHHHHHHHHHHTS.TSEEEEEETGGGHHHHHTT CS
         AAA   1 vllyGppGtGKTllakavakel..........g....vefleisgsellsk........yvgesekkirelfkeakeka.kpsilfiDEidalaksrsg 76 
                 +l+ G  G+GKT+l+k ++ ++          +    +++ +++g++ l++        +  e+   + +l k+a  +a +++  ++D +d++ + r +
  EEA21491.1 396 ILIRGRAGVGKTTLCKKIVYDFlyhqmwadlfDriiwIPLRRLKGMSDLDEffrheffkHEAERDGLVIKLRKTALDQAhTKTLWLLDGLDEVSGYR-N 493
                 57889****************544333333331333366777777777766777775445566666677777776666677799999******9999.7 PP

                 CCCHHHHHHHHHHHHH CS
         AAA  77 seseeeervvnqLlte 92 
                  +  + +++ n Ll+e
  EEA21491.1 494 PSGADLTEIFNSLLNE 509
                 7888889999999886 PP

>> Cohesin_HEAT  HEAT repeat associated with sister chromatid cohesion
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0       0.2   2.3e+02      22      42 .]     907     927 ..     904     927 .. 0.89
   2 ?    9.0   0.2    0.0015       1.8      16      42 .]     934     961 ..     933     961 .. 0.91

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.2
                   HHHHHHHSS-HHHHHHHHHHH CS
  Cohesin_HEAT  22 tiarrltDsspsVRdAaLell 42 
                   ++a+ + Ds p VR Aa++ l
    EEA21491.1 907 IVANFMGDSYPDVRRAAIKAL 927
                   6889999**********9875 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.0015
                   SHHHHHHHHHHH.HSS-HHHHHHHHHHH CS
  Cohesin_HEAT  16 apevldtiarrl.tDsspsVRdAaLell 42 
                   +p++l++++rrl +D++  VR Aa+e l
    EEA21491.1 934 SPDILKAVIRRLeNDEDLDVRRAAIEVL 961
                   69**********56***********975 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00036      0.43       1      18 [.     396     413 ..     396     517 .. 0.78
   2 ?   -0.8   0.0       1.8   2.2e+03      50      95 ..     943     988 ..     902    1012 .. 0.67

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00036
      AAA_18   1 IlltGtpGvGKttlakeL 18 
                 Il+ G +GvGKttl+k +
  EEA21491.1 396 ILIRGRAGVGKTTLCKKI 413
                 8999************98 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 1.8
      AAA_18  50 krldedkldklldaleenssaleegknlvidghlaeleseaakdik 95 
                 +rl+ d +  + +a  e   ++ + ++ +++ ++++le e++ d+ 
  EEA21491.1 943 RRLENDEDLDVRRAAIEVLGTQSSWSPDILEAVICQLENEKYSDLA 988
                 3333333333444444433355568888999999999999988766 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   9.6e-05      0.11       1      20 [.     395     414 ..     395     421 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 9.6e-05
                 EEEEE--TTSSHHHHHHHHH CS
    NTPase_1   1 kvfiTGppGvGKtTlvkkvl 20 
                 +++i G+ GvGKtTl+kk++
  EEA21491.1 395 RILIRGRAGVGKTTLCKKIV 414
                 5899**************97 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00025      0.29       3      28 ..     394     419 ..     392     430 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00025
      AAA_24   3 lkiliyGpsgiGKTtlakelgpkplf 28 
                 ++ili G +g+GKTtl+k++ +++l+
  EEA21491.1 394 RRILIRGRAGVGKTTLCKKIVYDFLY 419
                 79****************99777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1088 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       482  (0.0268838); expected 358.6 (0.02)
Passed bias filter:                      448  (0.0249875); expected 358.6 (0.02)
Passed Vit filter:                        87  (0.00485247); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.79u 0.30s 00:00:01.09 Elapsed: 00:00:00.45
# Mc/sec: 7297.91
//
Query:       EEA21492.1  [L=238]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.7e-31  106.5   0.0    1.5e-30  105.9   0.0    1.2  1  DDE_3            DDE superfamily endonuclease
      1e-07   31.5   0.0    7.2e-07   28.8   0.0    2.3  2  HTH_33           Winged helix-turn helix
    0.00046   20.4   0.0     0.0012   19.1   0.0    1.7  1  rve              Integrase core domain
    0.00063   19.4   0.0    0.00091   18.9   0.0    1.2  1  DDE_1            DDE superfamily endonuclease
  ------ inclusion threshold ------
      0.054   12.5   0.1        6.8    5.6   0.0    2.2  2  DDE_Tnp_ISAZ013  Rhodopirellula transposase DDE domain


Domain annotation for each model (and alignments):
>> DDE_3  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  105.9   0.0   4.2e-34   1.5e-30       2     135 ..      59     193 ..      58     198 .. 0.95

  Alignments for each domain:
  == domain 1  score: 105.9 bits;  conditional E-value: 4.2e-34
       DDE_3   2 vvfiDEsgfqlgt.vrrrawakkGkrer.leeygrrgrvnligaldekgglafvtfeetlnaedfaeflerlletalqak...kivlilDnasiHkses 95 
                 +v++DEsg++ ++ +rr++w+++G  ++ ++e +r++r  ++ a+ ++g     +++++ +a+ f++f+e+ll++  + +   k vli+Dnas+H+s+ 
  EEA21492.1  59 LVYVDESGCDKRAgRRRTGWSPRGVAPVqISEFQRGQRYHILPAYAQDGVVLSRIYQGSTDAAVFEDFIEQLLHHCGR-WpaaKSVLIMDNASFHHSQI 156
                 89************************999********************9999**********************999.6689**************98 PP

       DDE_3  96 lrelveeeadrlellylPpySPelNpiEivwsklkrellk 135
                  +   e+   +++llylPpySP+lNpiE+++s lk  +++
  EEA21492.1 157 SQVCREA---GVKLLYLPPYSPDLNPIEEFFSELKGFIKR 193
                 8888666...*************************99987 PP

>> HTH_33  Winged helix-turn helix
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.8   0.0     2e-10   7.2e-07      11      52 ..       2      43 ..       1      45 [. 0.94
   2 ?   -0.8   0.0      0.35   1.3e+03      21      35 ..     150     164 ..     148     167 .. 0.87

  Alignments for each domain:
  == domain 1  score: 28.8 bits;  conditional E-value: 2e-10
      HTH_33 11 aqlieerfgvsysvsgvyrlLkrlGfsyqkPrprapkqdpea 52
                a l+e+rf v +s+s+++r+L + G+s+++ r++  ++d++ 
  EEA21492.1  2 ASLLEQRFAVAVSPSTISRMLTENGWSKKVIRQVSTRRDADL 43
                679************************************986 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.35
      HTH_33  21 sysvsgvyrlLkrlG 35 
                 s+++s++++  +++G
  EEA21492.1 150 SFHHSQISQVCREAG 164
                 899******999998 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   3.2e-07    0.0012      40     115 ..     112     187 ..      90     189 .. 0.78

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 3.2e-07
         rve  40 ealsdemdastvlalleravarfggve..pervlsDngseytskafrefladlgirvsftrpgrpqdnGkvErfhrtl 115
                  ++  ++da++  +++e+ + + g       ++++Dn+s +  +++ +++++ g+++ + +p++p+ n + E f+  l
  EEA21492.1 112 RIYQGSTDAAVFEDFIEQLLHHCGRWPaaKSVLIMDNAS-FHHSQISQVCREAGVKLLYLPPYSPDLNPI-EEFFSEL 187
                 555555667777777777766665544557899*****6.9999************************85.6666665 PP

>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.0   2.6e-07   0.00091      51     132 ..     115     195 ..     109     216 .. 0.83

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 2.6e-07
       DDE_1  51 kawltssifeeWL.kvfdkrleaekrkilLlldssrshetvelleselqniklvflPassasllqPldqgvvselKarYrrql 132
                 ++++++ +fe+++ + + ++ + +  k++L++d++  h+ + ++ +++  +kl++lP+ s + l P+++  +selK   +r +
  EEA21492.1 115 QGSTDAAVFEDFIeQLLHHCGRWPAAKSVLIMDNASFHHSQISQVCREAGVKLLYLPPYSPD-LNPIEE-FFSELKGFIKRTW 195
                 68999********888899999**************999666668************88876.577765.4577776665555 PP

>> DDE_Tnp_ISAZ013  Rhodopirellula transposase DDE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0    0.0019       6.8      34      71 ..       6      45 ..       1      58 [. 0.75
   2 ?    5.0   0.0    0.0028        10     204     238 ..     156     187 ..     126     198 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0019
  DDE_Tnp_ISAZ013 34 eqghk..vsaetvaelLkelgyslqsnrKtkegkkhpdrd 71
                     eq ++  vs++t++++L e+g+s++  r+  + ++   rd
       EEA21492.1  6 EQRFAvaVSPSTISRMLTENGWSKKVIRQVSTRRDADLRD 45
                     44444339***************99988888777776666 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.0028
  DDE_Tnp_ISAZ013 204 lqkladelgleiqvahfPpgtskwnkiEhRlfshi 238
                      + + ++e g  +++ ++Pp+    n+iE   fs +
       EEA21492.1 156 ISQVCREAG--VKLLYLPPYSPDLNPIE-EFFSEL 187
                      555566655..6789*************.777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (238 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       475  (0.0264934); expected 358.6 (0.02)
Passed bias filter:                      454  (0.0253221); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 1799.33
//
Query:       EEA21493.1  [L=438]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (438 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       482  (0.0268838); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 2841.14
//
Query:       EEA21494.1  [L=473]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0058   17.3   0.3      0.026   15.2   0.1    2.2  2  zf-RVT    zinc-binding in reverse transcriptase
  ------ inclusion threshold ------
      0.014   15.6   0.2       0.05   13.8   0.2    2.0  1  RNase_H   RNase H


Domain annotation for each model (and alignments):
>> zf-RVT  zinc-binding in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0      0.69   6.2e+03       4      25 ..     230     251 ..     229     265 .. 0.82
   2 !   15.2   0.1   2.9e-06     0.026      53      80 ..     353     380 ..     338     383 .. 0.78

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.69
      zf-RVT   4 ksaYkllrekkekvklakliWk 25 
                 +++Y+l+++ + + +  + iW 
  EEA21494.1 230 QRIYQLAQTLQRQENAINAIWV 251
                 5789999999999999999995 PP

  == domain 2  score: 15.2 bits;  conditional E-value: 2.9e-06
      zf-RVT  53 rgiesssrCqlCgqeeEtieHlfleCpf 80 
                 r  +++s  + Cgq+ Et+eH +++C++
  EEA21494.1 353 RIGAVDSDLCACGQASETVEHFLFRCTK 380
                 44445777789***************75 PP

>> RNase_H  RNase H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.2   5.6e-06      0.05      39     127 ..     176     257 ..     137     272 .. 0.64

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 5.6e-06
                 CCCHHHHHHHHHHHHHHHTT.SC...SEEEEEES-HHHHHHHHCCCHHHHHTTSSSETTSSBHTTHHHHHHHHHCHC.SSEEEEEE-SCCSSS CS
     RNase_H  39 eaqtnnraELsAvieaLkalksd...ekvniytDSkYvvkgitqwvhrwkknawkttseqkpvknkdlaellkelak.kkkvqlkwvkgHaGv 127
                  +q   +aEL A+ +aL++   +     ++i +  + ++ +i q          +++s q  v++  +++l+++l + +++++  wv++H+  
  EEA21494.1 176 TEQNPYTAELGAIAAALEHIPVGtcrRWITILSSNRSALAAISQ---------PRQQSGQ-KVIQ-RIYQLAQTLQRqENAINAIWVPAHTDM 257
                 23444579999999999986555322334455555445554444.........2234445.5999.899999888885778*********865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (473 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       790  (0.0440627); expected 358.6 (0.02)
Passed bias filter:                      490  (0.02733); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.42
# Mc/sec: 3413.67
//
Query:       EEA21495.1  [L=604]
Description: fungal specific transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.5e-14   53.7   0.7    2.8e-14   52.8   0.5    1.5  1  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.8   0.5   1.5e-18   2.8e-14       4     183 ..     101     286 ..      98     304 .. 0.79

  Alignments for each domain:
  == domain 1  score: 52.8 bits;  conditional E-value: 1.5e-18
  Fungal_trans   4 ffsnfhpqfpilhkpsflpkt...ssenssksayasplll..lailalGalfsesetkesnssltses.....qefiafplraeili.hedfsspss 89 
                   +f+ +++ fpi  k+ f+      ++++ss+++ as +    l  +al a+++ s+  +s + +   +     ++ i ++l  ++   ++  ++ s+
    EEA21495.1 101 YFTTINHNFPIWTKERFNQLAiamRQSESSEKDLASIICCnnLILMALSANSLCSHRVKSPQIKQAQKissidFDVIEGFLTNAKRAlNNLDQVVSP 197
                   9********************99955555555555555445555555555555555555544444444667789*******6666664566677788 PP

  Fungal_trans  90 slwilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinl 183
                   ++  +q+Ll l l+ + + +   +e ++ +avr+a+s+g h++ s  g     + + e++++rr++ ++ ++lDkti+   G  p+++ s+++l
    EEA21495.1 198 RVINVQALLSLFLVAQEFLSVGICETLFTLAVRCAKSIGVHQWHSLQG-----QISDEDIKERRNISYCLYVLDKTICWTAGSSPNIPISEVQL 286
                   8***********************************************.....466666**************************766666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (604 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       693  (0.0386525); expected 358.6 (0.02)
Passed bias filter:                      515  (0.0287244); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.44
# Mc/sec: 4158.47
//
Query:       EEA21496.1  [L=337]
Description: two-component sensor protein histidine protein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.1e-24   84.1   0.8    1.3e-23   83.3   0.8    1.4  1  Response_reg  Response regulator receiver domain
    4.7e-10   39.7   0.0    3.2e-06   27.3   0.0    2.3  2  PAS_4         PAS fold
    6.5e-09   36.0   0.0     0.0038   17.4   0.0    2.3  2  PAS_9         PAS domain
    2.7e-05   24.1   0.1     0.0061   16.6   0.0    2.4  2  PAS           PAS fold
  ------ inclusion threshold ------
       0.36   10.8   3.1        9.1    6.2   0.0    2.9  3  DUF1541       Protein of unknown function (DUF1541)


Domain annotation for each model (and alignments):
>> Response_reg  Response regulator receiver domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.3   0.8   3.6e-27   1.3e-23       2     110 ..     220     330 ..     220     332 .. 0.97

  Alignments for each domain:
  == domain 1  score: 83.3 bits;  conditional E-value: 3.6e-27
                   EEESSSHHHHHHHHHHHHHTTEEEEEEESSHHHHHHHHHHHH..ESEEEEESSCSSSEHHHHHHHHHHCTTTSEEEEEESSTSHHHHHHHHHCTESE CS
  Response_reg   2 livdDdplvrellrqlleeegyeevaeaedgkealellkeek..vdlillDinmpgmdGlellkeireedpelpviiltahseeedavealkagadd 96 
                   l+v+D+ ++++++ ++l+  g+e+v++a +g+ea++++k++   ++ il+Dinmp mdG++++  ir+ ++++p+i++t+++ + d  ++l  g++d
    EEA21496.1 220 LLVEDNIMIQTIMLKMLNIIGFEKVDTAWNGAEAVRKVKQKPlsYNAILMDINMPVMDGVDATIAIRRMSQDVPIIAMTGNALKGDSDAYLASGMND 316
                   79************************************999888***************************************************** PP

                   EEESSG-HHHHHHH CS
  Response_reg  97 flsKpfdpeeLlka 110
                   +++Kp+++++L++ 
    EEA21496.1 317 YIAKPVHRQHLVSV 330
                   **********9875 PP

>> PAS_4  PAS fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.0     9e-10   3.2e-06      27     108 ..      67     152 ..      61     154 .. 0.89
   2 !   10.0   0.0   0.00022      0.77       7      46 ..     180     219 ..     178     236 .. 0.85

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 9e-10
       PAS_4  27 lfgappeellGktlaellpee....daarleralrrvlegeepiefleelll.pgeerhyelrllPlrdesGevigvlvisrDiTer 108
                 +  ++++e++G+++++l p+     d + l+r ++++++++e ++  ++  + + +  +y+++++P+ d +G+ + v++ ++D+T +
  EEA21496.1  67 CCERTRAEVVGHSVYDLPPHKvpatDTTSLHRTIAHAIKTGELQIIDDIAIDnGIDYTVYSVHITPIQD-QGKLLYVVLSVHDVTKE 152
                 5567899*********988889******************************56667789*******65.***************76 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00022
       PAS_4   7 alavldpdgrvlyaNaaaaelfgappeellGktlaellpe 46 
                 a+++ld+ g v  +N  aa + g++ ++++G+++  ++ +
  EEA21496.1 180 AIFMLDTTGCVATWNSGAAMIKGYSSDDIIGRHFSTFYGD 219
                 6899******************************965544 PP

>> PAS_9  PAS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.0   1.1e-06    0.0038      26     104 .]      70     151 ..      55     151 .. 0.85
   2 !   16.4   0.0   2.2e-06     0.008       3      41 ..     180     219 ..     178     267 .. 0.84

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 1.1e-06
       PAS_9  26 yspeevlgksitdlf......vtdpeanerlraaleqgrkkerevevvlirkngetfwvlltaspvkdddgelvgiivilrDite 104
                  +++ev+g+s+ dl        +  + ++++++a+++g+   +  + + i++   +  + ++++p++d +g+l  +++ ++D+t+
  EEA21496.1  70 RTRAEVVGHSVYDLPphkvpaTDTTSLHRTIAHAIKTGE--LQIIDDIAIDNGIDYTVYSVHITPIQD-QGKLLYVVLSVHDVTK 151
                 6899**************999999999999999999999..6666666666655777778******75.689999********95 PP

  == domain 2  score: 16.4 bits;  conditional E-value: 2.2e-06
       PAS_9   3 gilidnpdgrilyaNeaalrllGyspeevlgksitdlf.v 41 
                 +i++ ++ g +  +N +a+ + Gys+++++g+++++++ +
  EEA21496.1 180 AIFMLDTTGCVATWNSGAAMIKGYSSDDIIGRHFSTFYgD 219
                 789988***999***********************99951 PP

>> PAS  PAS fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.3   0.0    0.0053        19      37     113 .]      71     149 ..      67     149 .. 0.80
   2 !   16.6   0.0   1.7e-06    0.0061      13      48 ..     180     215 ..     167     234 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0053
                 THHHCTTSBGGGGBSTTHHH....HHHHHHHHHHHHTT-ECCCCEEEECTTSSEEEEEEEEEEEEETTEEEEEEEEEEEES CS
         PAS  37 sreevlgkslldliheedda....elaelleqlleqgeesrageisfklrdgrpihlevraspvrdaggeilgflgvlrdi 113
                 +r ev+g s++dl +++ +a     l++ +  ++++ge + + +i ++     ++   v+ +p+ d g+  l++++ ++d+
  EEA21496.1  71 TRAEVVGHSVYDLPPHKVPAtdttSLHRTIAHAIKTGELQIIDDIAIDN-GIDYTVYSVHITPIQDQGKL-LYVVLSVHDV 149
                 789**********999999987778888888888888888888888888.66666667778899999665.5999999986 PP

  == domain 2  score: 16.6 bits;  conditional E-value: 1.7e-06
                 EEEEEETTSBEEEECHHHHHHHSSTHHHCTTSBGGG CS
         PAS  13 pifvvDedgrilyvNaaaeellGlsreevlgkslld 48 
                 +if++D  g++  +N+ a+ + G+s ++++g++++ 
  EEA21496.1 180 AIFMLDTTGCVATWNSGAAMIKGYSSDDIIGRHFST 215
                 89******************************9875 PP

>> DUF1541  Protein of unknown function (DUF1541)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.1       2.5   8.8e+03      14      26 ..      34      46 ..      33      48 .. 0.76
   2 ?    6.2   0.0    0.0025       9.1      22      43 ..     117     138 ..     114     140 .. 0.87
   3 ?    4.1   0.2     0.012        44       6      23 ..     267     284 ..     264     288 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 2.5
                TGTT-EEEEEEEE CS
     DUF1541 14 gMkgaeAtIdgae 26
                 Mk   A I+ a 
  EEA21496.1 34 DMKAVHAAIKFAI 46
                6999999998775 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.0025
                 EEEEEEEEEEEEEE--TTSSS- CS
     DUF1541  22 IdgaedttvYmVdytptdggek 43 
                 Id++ d tvY V  tp ++  k
  EEA21496.1 117 IDNGIDYTVYSVHITPIQDQGK 138
                 99999***********988765 PP

  == domain 3  score: 4.1 bits;  conditional E-value: 0.012
                 EE-S-SSTTGTT-EEEEE CS
     DUF1541   6 tltadHmegMkgaeAtId 23 
                 +l +  m+ M+g  AtI 
  EEA21496.1 267 ILMDINMPVMDGVDATIA 284
                 566667**********96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (337 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       586  (0.0326845); expected 358.6 (0.02)
Passed bias filter:                      484  (0.0269954); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2342.49
//
Query:       EEA21497.1  [L=1318]
Description: reverse transcriptase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.9e-33  115.8   0.0    3.8e-33  114.9   0.0    1.4  1  RVT_1            Reverse transcriptase (RNA-dependent DNA pol
    2.4e-22   79.0   0.0    5.3e-22   77.9   0.0    1.6  1  Exo_endo_phos_2  Endonuclease-reverse transcriptase
    3.8e-05   23.3   0.0    8.7e-05   22.1   0.0    1.6  2  Exo_endo_phos    Endonuclease/Exonuclease/phosphatase family
    0.00062   19.7   2.3    0.00062   19.7   2.3    2.4  2  zf-CCHC          Zinc knuckle


Domain annotation for each model (and alignments):
>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.9   0.0   8.5e-37   3.8e-33       5     220 ..     692     938 ..     686     940 .. 0.93

  Alignments for each domain:
  == domain 1  score: 114.9 bits;  conditional E-value: 8.5e-37
                 T....S-EEE......-THHHHCTB--...........-------HHHH.................HCCHTS--EEEEEEBCCGCCCSBB-GGGGGGG- CS
       RVT_1   5 g...pgsyRpisllsvdykalnkliakrLkdvl..ekllsenqpgfrpgrstldav....edllkalkkkkkaklllklDlkkaFdsvpleellrklta 94 
                 +   ++ +Rpislls+++k+l+++ia+r++ ++    ll++n +g r+ rs ++a+    e++ ka ++++k   l+++D+++ ++ v  e+ll++l+a
  EEA21497.1 692 NyslAKAWRPISLLSTLGKILEAVIAERISYAVetFGLLPTNHFGARKRRSAEQALlllqEEIFKA-WRNRKVLSLVSFDVQGEYNGVFKERLLQRLKA 789
                 3566799**************************88899*********************7667776.******************************** PP

                 EEET..........................TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T......TEEECTTEEEEEESSHHH......HHHHHHH CS
       RVT_1  95 fkvptklinliksflstrsfsvrvnge.eskgryekkglpqGsvlSPllfnlfmnellrelrkrakgvtllrYaDDililskskee......lqellea 186
                  ++p+k++++i++f s r++++ vng  + ++  +++glpqGs+lSP+lf +f  +l ++  ++  +   ++++DD +  ++++++      ++++++ 
  EEA21497.1 790 RGIPDKIVQWINAFCSRRTATILVNGLtSEQRELSQAGLPQGSPLSPILFLFFNADLVQHRISA--SGGSIAFVDDYTAWVTGPSAeanragIEAVINR 886
                 ************************9996777778899*********************999996..8999*************9999************ PP

                 HHHHHHHTT--BEGGG-EEE.......................ESSEEETTE CS
       RVT_1 187 veewlkesglkinpeKtklvlft.................v.kseevkyLGv 220
                   ew ++sg +++ +Kt +v+ft                 v  +++ k+LGv
  EEA21497.1 887 ALEWERRSGATFEYDKTAIVHFTrtasrssstlftvkgvtVkPKDSAKILGV 938
                 *************************999999999988876478999999998 PP

>> Exo_endo_phos_2  Endonuclease-reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.9   0.0   1.2e-25   5.3e-22       2     118 ..     287     413 ..     286     414 .. 0.91

  Alignments for each domain:
  == domain 1  score: 77.9 bits;  conditional E-value: 1.2e-25
  Exo_endo_phos_2   2 liisvYippsd......elenlestlekllselksp.kiiilGDfNakhplWgsedtds..sargeeLiefleehslsllnllksg.ptfkssn 85 
                      l++svY++ ++      +++ l++ + ++  + + + +++i+GDfN++++lWg+ + +   + ++e L+++++ehsl+  +ll++g +t++s +
       EEA21497.1 287 LVVSVYVEGNNkealisTTRLLHDLVVDIRGRDGIRtDVLIVGDFNRHDQLWGGDQISParQGEAEVLVDYITEHSLQ--SLLPRGtKTWHSGD 378
                      799**********999888888888888888888889*****************65555999****************..99999968888877 PP

  Exo_endo_phos_2  86 gsstiDltltsdnlals..kleleeedlgSDHrpi 118
                       ++tiDl+l+s++la++  k+ ++ +++gSDH++i
       EEA21497.1 379 LETTIDLVLASTELAEEmvKCGIHYTNHGSDHQAI 413
                      7*******************************998 PP

>> Exo_endo_phos  Endonuclease/Exonuclease/phosphatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.1   0.0   1.9e-08   8.7e-05     122     233 .]     300     410 ..     201     410 .. 0.80
   2 ?   -3.4   0.0       1.3   5.7e+03     115     147 ..     716     763 ..     655     764 .. 0.69

  Alignments for each domain:
  == domain 1  score: 22.1 bits;  conditional E-value: 1.9e-08
                    HHHHHHHHHHHHHHHHHHHHHTTSEEEEEEE-SSSTSGGGBSCGHHHHHHCTTTHH......SSCESCETTTTTTTTTTTEB-BEEEEEECHHHCC CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Exo_endo_phos 122 dlvrdlqllalllqvealnadrgapvivaGDfNarpsdddsrvlrtrglalapapv......glyllgggptptyvtraggsrlDrilaspalalf 211
                    +l   ++ll++l   +++ ++    v+++GDfN +   ++   + +++   a+++v       l++l +  t t+++     ++D +las++la +
     EEA21497.1 300 ALISTTRLLHDLVVDIRGRDGIRTDVLIVGDFNRHDQLWGGDQISPARQGEAEVLVdyitehSLQSLLPRGTKTWHSGDLETTIDLVLASTELAEE 395
                    555667888999999999999999*******************************88999*******************************99988 PP

                    EEEEEEECCHHEECTSSCSSSB CS
                    xxxxxxxxxxxxxxxxxxxxxx RF
  Exo_endo_phos 212 rsgvlppplalvrrealtlSDH 233
                     +  ++++ +        +SDH
     EEA21497.1 396 MVKCGIHYTNH-------GSDH 410
                    88888887654.......6888 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 1.3
                    E...............CCCHHGHHHHHHHHHHHHHHHHHHHHHTTSEE CS
                    x...............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Exo_endo_phos 115 i...............ashrdhdlvrdlqllalllqvealnadrgapv 147
                    i                 h   + +r +++++lllq e++ a+r+++v
     EEA21497.1 716 IaerisyavetfgllpTNHFGARKRRSAEQALLLLQEEIFKAWRNRKV 763
                    144444444455555566777788889999999999999998888776 PP

>> zf-CCHC  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   2.3   1.4e-07   0.00062       2      18 .]     136     152 ..     135     152 .. 0.93
   2 ?   -0.2   3.4      0.28   1.3e+03       2      12 ..     155     165 ..     154     170 .. 0.83

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 1.4e-07
                 CTSSSSSSSSTTTTSTS CS
     zf-CCHC   2 kCynCGepGHiardCpk 18 
                 +C+nC+e+GH a  C+k
  EEA21497.1 136 QCFNCQEMGHKAYSCKK 152
                 7**************96 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.28
                 CTSSSSSSSST CS
     zf-CCHC   2 kCynCGepGHi 12 
                 +C +C   GH 
  EEA21497.1 155 TCAKCAVKGHH 165
                 8*********7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1318 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       885  (0.0493614); expected 358.6 (0.02)
Passed bias filter:                      620  (0.0345808); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.94u 0.33s 00:00:01.27 Elapsed: 00:00:00.52
# Mc/sec: 7568.14
//
Query:       EEA21498.1  [L=228]
Description: NUDIX domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.9e-16   58.1   0.4    1.4e-15   57.5   0.4    1.2  1  NUDIX     NUDIX domain
  ------ inclusion threshold ------
      0.087   12.8   0.0       0.27   11.2   0.0    1.9  1  NUDIX_4   NUDIX domain


Domain annotation for each model (and alignments):
>> NUDIX  NUDIX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.5   0.4   1.5e-19   1.4e-15      16     121 ..      80     196 ..      72     204 .. 0.79

  Alignments for each domain:
  == domain 1  score: 57.5 bits;  conditional E-value: 1.5e-19
                 E..EEEEEES.SSSTTT.EESSEEECBTTS.HHHHHHHHHHHHHHSEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE.......EEECSGCSST... CS
       NUDIX  16 e..vLlvrrs.kkpfpg.WelPgGkvepgE.tpeeAArREleEEtGleaellellgrlhylapydgpygdeheilyvfl.......eevegelepn... 99 
                    +L+++r+ ++ f g W++PgG ++p + t+ + ++RE++EEtGl +  ++ ++r++++  ++        +++v+         e+e+    +   
  EEA21498.1  80 ShlMLIIQRAfDDSFGGyWDFPGGSLDPEDqTLLDGVAREVFEETGLHVSKIRDIARIDEWIEPKSLGLV-GKFSFVVDvheaadtMEWEE----Kikl 173
                 24699******99***************999****************99***************999996.44444444533444444444....2555 PP

                 STTTEEEEEEEEHHHH.HHHHTH CS
       NUDIX 100 denevsevrwvpleel.lkekla 121
                 d+ e+ ++ wv  ee+ + ++l+
  EEA21498.1 174 DPREHVKWLWVGEEEIeKSARLR 196
                 6***************5444444 PP

>> NUDIX_4  NUDIX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0     3e-05      0.27      11      42 ..      83     116 ..      76     195 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 3e-05
                 EEEEE--TTSSSTT-EE-SEEE-TTS-..HHHHH CS
     NUDIX_4  11 vllekRpekgllggLwefPggeeegee..leeal 42 
                  l+ +R  ++  gg w fPgg  + e+  l + +
  EEA21498.1  83 MLIIQRAFDDSFGGYWDFPGGSLDPEDqtLLDGV 116
                 6899***************988554441122222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (228 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       290  (0.0161749); expected 358.6 (0.02)
Passed bias filter:                      270  (0.0150594); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 1624.41
//
Query:       EEA21499.1  [L=475]
Description: dipeptidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   3.2e-102  342.0   0.0   3.8e-102  341.7   0.0    1.0  1  Peptidase_M19  Membrane dipeptidase (Peptidase family M19)


Domain annotation for each model (and alignments):
>> Peptidase_M19  Membrane dipeptidase (Peptidase family M19)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  341.7   0.0  2.1e-106  3.8e-102       3     319 .]      84     445 ..      82     445 .. 0.98

  Alignments for each domain:
  == domain 1  score: 341.7 bits;  conditional E-value: 2.1e-106
                    HCCS.EEEEEE-HHHHHHHCTTTTT........-TTTHCTSSS-HHHHHHHTEEEEEEEEE--C........CCCCCCHHHHHHHHHHHHHHHHHH CS
  Peptidase_M19   3 lkkliviDghndlplklrqekkesl........llekdselqtdlerlraggvsavlfaifvpe........dasyeeavkatleqidlirrlvrk 82 
                    l+++++iDghndlp+ +r+   ++         +  ++  +++d++rl +g+v+++++++fvp+        +++y e+v++t eq+d+++r+ ++
     EEA21499.1  84 LSETPLIDGHNDLPILVRAMYGNKIyssdfikrFAFGNLTGHVDAPRLADGQVGGTFWSVFVPCpadgadfsKENYAESVRTTYEQVDVMTRIQQE 179
                    6789**************9999988999*99999999***********************************99********************** PP

                    GTTTEEE-SSHHHHHHHHHTT-EEEEEEEESCGGGTT-HHHHHHHHHTTEEEEES-SSS-BSSB-BCCGTT..........SSSSB-HHHHHHHHH CS
  Peptidase_M19  83 npeqlklvrtaddierakkegkiavllgiegaealgddlallrafyalGvrvlgltynrnnkfAdgaleek.........dedgGLsefGkelVre 169
                    +++ l+   +   + + +++gki + lgieg++++g++l+ lr+fy+lGvr+++lt+n++n +Ad+al e            ++G+se Gk lV e
     EEA21499.1 180 FKGILSESPNGTTALEEFRRGKIISPLGIEGLHSIGNSLTHLRSFYKLGVRYATLTHNCHNIYADAALVEIpgggikkadPVWNGVSEKGKILVSE 275
                    ***********99999****************************************************9989*****99999************** PP

                    HHHHT-EEE-TTB-HHHHHHHH.......HH-SSE.EECCEEBTTTS--TTSB-HHHHHHHHHTT-EEEE-SSHHHCTTT.............S-- CS
  Peptidase_M19 170 lNrlgiliDlShlsektfldvl.......elSkaPvvaSHSnaralcdhpRNltDeqlkaiaesgGvvgvtfvpaflkek.............aea 245
                    +Nrlg+++Dl+h+se+t++dvl         S+aPv++SHS+ +alc+hpRN tDe+lk+++++++vv+v+f+p+f++++             ++a
     EEA21499.1 276 MNRLGMIVDLAHVSEATMHDVLgagkddwIGSQAPVIFSHSSTHALCPHPRNPTDETLKLVKKTDSVVMVNFYPQFISCTasdredgmpdfyaPNA 371
                    **********************999998889***************************************************************** PP

                    BHHHHHHHHHHHHHHT-GGGEEE---TTTTSS-BBTBSSGGGHHHHHHHHHHTTS-HHHHHHHHTHHHHHHHHH CS
  Peptidase_M19 246 tledvvdhidyivelaGidhVGlGsDfdgggelpegledvsklpnltaeLlrrgyseadiekilggNflrvlee 319
                    tl +v++hi +i +l+G dhVGlGsDfdg++ +pegledvsk+p+l+aeLlrrg s++d +k++ggN+lrv+++
     EEA21499.1 372 TLAHVANHIMHIGNLIGFDHVGLGSDFDGIESTPEGLEDVSKYPDLIAELLRRGVSDSDAAKVAGGNLLRVWKK 445
                    ************************************************************************85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (475 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       381  (0.0212505); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.31s 00:00:00.87 Elapsed: 00:00:00.50
# Mc/sec: 2849.31
//
Query:       EEA21500.1  [L=768]
Description: flavodoxin and radical SAM domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.1e-22   79.3   0.1    1.4e-21   77.6   0.0    2.0  2  Radical_SAM   Radical SAM superfamily
    5.8e-22   77.8   0.0    1.2e-21   76.8   0.0    1.6  1  Wyosine_form  Wyosine base formation
      6e-08   33.0   0.0    4.5e-06   26.9   0.0    2.5  2  Flavodoxin_1  Flavodoxin


Domain annotation for each model (and alignments):
>> Radical_SAM  Radical SAM superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.6   0.0   2.4e-25   1.4e-21       3     166 ..     435     617 ..     433     618 .. 0.90
   2 ?   -4.1   0.0         3   1.8e+04     118     142 ..     695     719 ..     686     720 .. 0.68

  Alignments for each domain:
  == domain 1  score: 77.6 bits;  conditional E-value: 2.4e-25
                  EESEESS--TTTSCCTT..HHHHHHHHHHHHHHHHHHHHHHHHHTTSEEEEEE........................SSTGGGSTTHHHHHHHHHHTC CS
                  xxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........................xxxxxxxxxxxxxxxxxxxxx RF
  Radical_SAM   3 vtrgCnlrCsfCarpet..vrregrgrslsveeileevkelkaekgvkevilg........................ggepllypdfvellerlakla 74 
                  ++  C+++C+fC+r+ t  v++++r+++ ++e+i + vke++     k + ++                         gep++yp++ e+l +l+ + 
   EEA21500.1 435 PSLSCSNKCVFCWRHGTnpVGTTWRWKVDPPEMIFNGVKEGH----YKKIKMLkgipgvraerfaeamrirhcalslVGEPIFYPHINEFLGMLHNE- 527
                  6678*************************************8....555555555699999999999999999999********************8. PP

                  CCTEEEEEEECSSCHGHHHHHHHHHTT-SEEEEEEBSSSHH...HHHHHHTCTSHHHHHHHHHHHHHHTTSET.EEEEEEEBTTTS.HHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxx.xxxxxxxxxx RF
  Radical_SAM  75 vpgiritvetngtlpdeeklerllelgvdrvslgleaadde...kvlklmnrghtfeevlealeklreagikr.vvdrivglpGen.deeleellel 166
                     i+ ++++n+ +p  ++l++l++  v++++++++a + e   ++ +++  ++ +e++ ++l++lre++    +v+r+++++G+n d+e++e+++l
   EEA21500.1 528 --QISSFLVCNAQHP--DQLATLDR--VTQLYVSIDASNREslrRIDRPL-HRDFWERFQRCLDILREKRHFQrTVFRLTLVKGFNiDDEVKEYADL 617
                  ..9***********5..78888888..9*************999999999.66***************997777************55777777776 PP

  == domain 2  score: -4.1 bits;  conditional E-value: 3
                  HHHHTCTSHHHHHHHHHHHHHHTTS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxx RF
  Radical_SAM 118 lklmnrghtfeevlealeklreagi 142
                    + + + +++++ e+lek +  gi
   EEA21500.1 695 DGRWHTRINYDRFFELLEKEKTEGI 719
                  4445566888999999988777665 PP

>> Wyosine_form  Wyosine base formation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.8   0.0     2e-25   1.2e-21       1      62 [.     620     688 ..     620     689 .. 0.91

  Alignments for each domain:
  == domain 1  score: 76.8 bits;  conditional E-value: 2e-25
                   HHT-SEEEEEE--------...----------HHHHHHHHH....HHHTSSS.EEEEEEETTTTEEEEE CS
  Wyosine_form   1 kaepdFvEvKaytyvGssr...srLtmknvPwheevadfak....rlegsaedYellaehrhSrvvlla 62 
                   k+ p+F+EvK++ty+G+s      LtmknvP++eev+ f+     +le++++ Y++ aeh+hS+++lla
    EEA21500.1 620 KGLPCFIEVKGVTYCGTSSsagVGLTMKNVPFYEEVVAFVValndELERRGLGYGIGAEHAHSCCILLA 688
                   689****************88889*****************66666666666****************9 PP

>> Flavodoxin_1  Flavodoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0     0.013        80       1      25 [.     118     142 ..     118     153 .. 0.89
   2 !   26.9   0.0   7.5e-10   4.5e-06      51     143 .]     191     286 ..     156     286 .. 0.73

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.013
                   EEEETSSSHHHHHHHHHHHHHHHTT CS
  Flavodoxin_1   1 ilYgSetGnteklAkqlaeelgehg 25 
                   i+++S t +t++ A+ l e+l+ ++
    EEA21500.1 118 IFFASLTASTQTHAQWLLEQLRTAA 142
                   8********************9755 PP

  == domain 2  score: 26.9 bits;  conditional E-value: 7.5e-10
                   EEEEEETTTBEEGGGHHHHHHHHHHHCHHGCCSTTTTEEEEEEEEECTTSSS.....TTHHHHHHHHHHHH.TTCEEESSSEEEETTSTHGHHHHHH CS
  Flavodoxin_1  51 vvtsTfgnGdppengesffqdllelkgdeledgdlsgvrfavfglGdsayen.....Fcaagkkldeklee.lGaerllkllegdednqegqeeafr 141
                   + ++T++ + + ++   + ++  ++++  ++++  s   ++vfg+Gd+++++     Fc  +k++d ++ +  G +r  +l+ gd ++  +   a++
    EEA21500.1 191 FLIPTYNIDTIIDTFIAHLDETHNDFR-IDTAPLSSLAGYSVFGFGDKEGWPteedgFCSQAKEIDRWMAKlTGKKRAYPLGMGDTKT--DAINALK 284
                   555555555555554444444444442.25555556678********************************66889999******999..6666666 PP

                   HH CS
  Flavodoxin_1 142 kW 143
                    W
    EEA21500.1 285 DW 286
                   66 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (768 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       524  (0.0292264); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.68u 0.26s 00:00:00.94 Elapsed: 00:00:00.45
# Mc/sec: 5151.89
//
Query:       EEA21501.1  [L=292]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.9e-35  120.5   1.3    7.6e-35  120.1   1.3    1.1  1  adh_short     short chain dehydrogenase
    9.5e-35  120.2   0.1    1.2e-34  119.9   0.1    1.1  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
    7.5e-06   26.0   0.3    9.9e-06   25.6   0.3    1.3  1  KR            KR domain
     0.0089   15.9   1.3      0.013   15.3   1.3    1.3  1  3HCDH_N       3-hydroxyacyl-CoA dehydrogenase, NAD binding do


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  120.1   1.3   1.7e-38   7.6e-35       1     188 [.      19     211 ..      19     217 .. 0.93

  Alignments for each domain:
  == domain 1  score: 120.1 bits;  conditional E-value: 1.7e-38
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---S......S--SSG CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGi......tgsgpf 93 
                 kvv+vtG++sG+G+aia+ +a +Gakv++ +r++++le++a +++ +   +++iq+Dv+++e ++a+ve + +k  ++ ++ n ++       +  ++ 
  EEA21501.1  19 KVVVVTGGGSGLGKAIAEGFAVNGAKVYISGRRKDTLETAARQIGGD---IHIIQGDVQTAEGCKAIVESISAKESHVSAFQNSTASsshtdgKSACAH 114
                 89******************************************975...*********************************9999898776566666 PP

                 GGCSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGG..TSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHH CS
   adh_short  94 selseeewervievNltgvflltravlpamlkqssGrIvnvsSvag..kvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmak 188
                 s+++ +   + ++vN++gv+ lt  ++p + k++  ++  ++S ag  + ++ g   Y+ sKaav++l++ la  ++p +irvn+++PG++ ++m+ 
  EEA21501.1 115 SKHDTQSLTNRYSVNVNGVYFLTVNFIPLLRKSKDPNVCVIASLAGlgNIRSMGSLTYGVSKAAVVHLSKLLAGRFHPMKIRVNTICPGIFPSEMTG 211
                 66777778888**********************************955667788899***********************************99985 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.9   0.1   2.8e-38   1.2e-34       4     232 ..      28     268 ..      23     269 .. 0.88

  Alignments for each domain:
  == domain 1  score: 119.9 bits;  conditional E-value: 2.8e-38
                   TSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSEE..EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EG....CSS-GGGH-HHH CS
  adh_short_C2   4 sgIGraiAkalaeeGaevvltdlneeakkrveelaeelgaev..lecDVtdeeqvealveevvekfgklDilvnnagiapk....lkgpfletsree 94 
                   sg+G+aiA+ +a +Ga+v ++ ++++    +e++a+++g ++  ++ DV+  e ++a+ve + +k  ++  + n+ + + +          + + ++
    EEA21501.1  28 SGLGKAIAEGFAVNGAKVYISGRRKDT---LETAARQIGGDIhiIQGDVQTAEGCKAIVESISAKESHVSAFQNSTASSSHtdgkSACAHSKHDTQS 121
                   8*****************999999887...99999999999556************************************98632222333346778 PP

                   HHHHHHHHTHHHHHHHHHHHHHCTSC..CEEEEEEEGGGTSBSTTTT..HHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTTHHH CS
  adh_short_C2  95 fdraldvnlyslfllakaalplmkeg..gsivnlssvgaervvpnyn..aygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikgfde 187
                   + +  +vn+++++ l+  ++pl++++   ++  ++s+++   + +     yg++Kaa+++l++ lA  + p +iRvN+++pg+   +++   +g++e
    EEA21501.1 122 LTNRYSVNVNGVYFLTVNFIPLLRKSkdPNVCVIASLAGLGNIRSMGslTYGVSKAAVVHLSKLLAGRFHPMKIRVNTICPGIFPSEMTGVTAGKHE 218
                   888899***************88877789999******99999988888**************************************9887777444 PP

                   .....HHHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEESTT CS
  adh_short_C2 188 .....lleelearaplgrlgtpeevaeaalfLasdeasyitGqtlvvDgG 232
                          e+++ r+ +gr g+pee+   +l L s+   y++ + l vDgG
    EEA21501.1 219 yninhQAEKAALRSTVGRPGRPEEMVGPVLLLSSPGGGYMNCALLTVDGG 268
                   3322267777788899*********************************9 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.3   2.2e-09   9.9e-06       3      86 ..      21      97 ..      19     183 .. 0.77

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 2.2e-09
                EEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEE CS
          KR  3 ylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvi 86
                +++tGG  gLG+++a+  a +ga+ + + +R++      ++l ++ ++ g ++++++ Dv  ++  +a++e+i+a+e+ ++   
  EEA21501.1 21 VVVTGGGSGLGKAIAEGFAVNGAK-VYISGRRK------DTLETAARQIGGDIHIIQGDVQTAEGCKAIVESISAKESHVSAFQ 97
                79********************96.78899992......3344566888**************************998887654 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   1.3     3e-06     0.013       2      75 ..      21      94 ..      19     101 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 3e-06
                EEEE--SC.CHHHHHHHHHHTT-EEEEE-S-HHHHHHHHHHHHHHHHCCTTTTSS-HHHHCCCHHCEEEES-HHH CS
     3HCDH_N  2 vaviGaGt.mGagiaavfasagleVvlvdiseealekalekieksleklvekgklkeeeveaalarisfttdlee 75
                v v G G  +G+ ia+ fa +g +V +  +++++le+a+++i   ++  + + + ++e ++a+++ is++++  +
  EEA21501.1 21 VVVTGGGSgLGKAIAEGFAVNGAKVYISGRRKDTLETAARQIGGDIHIIQGDVQ-TAEGCKAIVESISAKESHVS 94
                5677887659*********************************98887654444.45888888888888776555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (292 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       590  (0.0329076); expected 358.6 (0.02)
Passed bias filter:                      437  (0.0243739); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.48u 0.30s 00:00:00.78 Elapsed: 00:00:00.47
# Mc/sec: 1848.84
//
Query:       EEA21502.1  [L=270]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
  ------ inclusion threshold ------
      0.021   14.8   0.1      0.053   13.6   0.1    1.7  1  Sulf_coat_C  Sulfolobus virus coat protein C terminal
        2.8    6.1   7.6        3.4    5.8   7.6    1.1  1  DUF2070      Predicted membrane protein (DUF2070)


Domain annotation for each model (and alignments):
>> Sulf_coat_C  Sulfolobus virus coat protein C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   5.9e-06     0.053      10      51 ..     204     245 ..     196     262 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 5.9e-06
  Sulf_coat_C  10 itGpnraiyqGfGlkiaralnriGsGpalvnminGlksyyis 51 
                  ++Gp+ ++y+ + + +ar   +  +G a++n i Gl   + s
   EEA21502.1 204 VAGPQISLYKTLNMHMARPYPKRAAGVAMINAIGGLSNVWTS 245
                  79**********************************987766 PP

>> DUF2070  Predicted membrane protein (DUF2070)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   7.6   0.00038       3.4      77     171 ..     114     212 ..      93     242 .. 0.74

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.00038
     DUF2070  77 ltelivviisllaillsallqalvllalvlslalvfalrllvlvavsdesllkavlpaliqpllailllvly......fspesfllllllslifalavy 169
                 +++ +++ + ++++++  l   ++ + ++l  a   +l+ +v++++s  s ++++lp+ + +l+++++++++      ++  +f+++l+ +++ +  + 
  EEA21502.1 114 MSQAMSSTVNFFPTIVRSL--GFSKNITLLLTAPPYILVAIVFYIISYISRTNMILPVHLFSLAIAVVAYVIsictlkLGGRYFAMMLMPCVVAGPQIS 210
                 5666666677777777653..344455555567789999999*****************9999999999999888887555666666666666655555 PP

     DUF2070 170 lf 171
                 l+
  EEA21502.1 211 LY 212
                 54 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (270 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       598  (0.0333538); expected 358.6 (0.02)
Passed bias filter:                      241  (0.0134419); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 1811.52
//
Query:       EEA21503.1  [L=101]
Description: hypothetical protein PMAA_053120 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.9e-12   45.5   0.1    5.7e-12   45.0   0.1    1.3  1  DUF4219   Domain of unknown function (DUF4219)


Domain annotation for each model (and alignments):
>> DUF4219  Domain of unknown function (DUF4219)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.0   0.1   3.2e-16   5.7e-12       3      27 .]      38      62 ..      36      62 .. 0.95

  Alignments for each domain:
  == domain 1  score: 45.0 bits;  conditional E-value: 3.2e-16
     DUF4219  3 gtNYatWklrMklyLiaqdLWevVe 27
                ++N ++WklrM+ +L++qd+W+vVe
  EEA21503.1 38 RSNIKNWKLRMQIFLETQDCWDVVE 62
                69**********************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (101 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       581  (0.0324056); expected 358.6 (0.02)
Passed bias filter:                      428  (0.0238719); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.44
# Mc/sec: 690.21
//
Query:       EEA21504.1  [L=172]
Description: hypothetical protein PMAA_053130 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (172 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       377  (0.0210274); expected 358.6 (0.02)
Passed bias filter:                      270  (0.0150594); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.29s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1137.02
//
Query:       EEA21505.1  [L=1212]
Description: kinesin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
   1.1e-104  339.8   1.6    2.7e-11   42.9   0.0   10.6 10  TPR_10       Tetratricopeptide repeat
    2.3e-99  325.8  11.3    7.7e-14   51.7   0.1    8.8 10  TPR_12       Tetratricopeptide repeat
    1.2e-34  115.8   0.4     0.0077   16.2   0.0    9.6  9  TPR_7        Tetratricopeptide repeat
    5.8e-23   79.1   4.6        1.4    9.2   0.0   10.4 10  TPR_2        Tetratricopeptide repeat
    7.6e-21   73.0  10.6       0.91    9.4   0.0    9.6  9  TPR_1        Tetratricopeptide repeat
      5e-18   65.4   0.0        2.4    8.7   0.0    9.2  9  TPR_19       Tetratricopeptide repeat
      2e-14   53.7  12.3    4.3e-08   32.9   1.8    3.8  4  TPR_MalT     MalT-like TPR region
    3.7e-12   45.7  15.9        0.4   11.2   0.0    9.6  9  TPR_17       Tetratricopeptide repeat
    3.2e-09   37.3   1.0         29    5.4   0.0    8.9  9  TPR_16       Tetratricopeptide repeat
    4.8e-09   35.7  12.2         19    5.8   0.1    9.9  9  TPR_8        Tetratricopeptide repeat
    9.8e-09   35.5   0.1       0.28   11.4   0.0    5.6  5  TPR_5        Tetratrico peptide repeat
    2.7e-08   33.3   0.0    9.1e-08   31.6   0.0    1.9  1  NB-ARC       NB-ARC domain
    6.3e-08   32.7   1.4    2.3e-06   27.6   0.3    3.0  2  NACHT        NACHT domain
    1.1e-07   31.3   0.0    5.2e-07   29.1   0.0    2.1  1  PNP_UDP_1    Phosphorylase superfamily
    1.4e-07   31.3   0.0         28    4.8   0.0    6.9  7  TPR_3        Tetratricopeptide repeat
    9.2e-07   28.9   0.0        6.6    7.7   0.0    7.4  7  TPR_4        Tetratricopeptide repeat
    2.1e-06   27.9   0.3        5.2    7.4   0.0    7.2  6  ANAPC3       Anaphase-promoting complex, cyclosome, subunit 3
    6.2e-06   26.6   2.7         48    5.1   0.0    8.2  7  TPR_14       Tetratricopeptide repeat
    6.8e-05   23.1   0.9         47    4.4   0.1    7.4  8  DUF4074      Domain of unknown function (DUF4074)
    0.00027   21.3   0.0      0.002   18.5   0.0    2.4  1  AAA_16       AAA ATPase domain
     0.0056   16.9   0.0      0.019   15.2   0.0    1.9  1  AAA_22       AAA domain
     0.0098   15.4  10.7         13    5.4   0.1    7.0  8  DUF1897      Domain of unknown function (DUF1897)
  ------ inclusion threshold ------
      0.031   14.0   5.2         62    3.3   0.0    5.9  7  Urocanase_N  Urocanase N-terminal domain
      0.065   13.0   0.3       0.21   11.3   0.3    2.0  1  Imm49        Immunity protein 49
       0.09   13.5  14.7      1e+02    3.8   0.0    9.0  9  TPR_6        Tetratricopeptide repeat
       0.13   12.1   1.5         13    5.6   0.0    3.7  5  DUF3574      Protein of unknown function (DUF3574)
       0.23   11.4   1.6         51    3.7   0.0    3.8  4  DUF4919      Domain of unknown function (DUF4919)
        2.1    7.9   9.6         41    3.7   0.1    4.3  5  DUF3157      Protein of unknown function (DUF3157)


Domain annotation for each model (and alignments):
>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   1.4e-05    0.0088      12      41 ..     721     750 ..     713     751 .. 0.91
   2 !   29.6   0.0   6.8e-10   4.4e-07       1      41 [.     752     792 ..     752     793 .. 0.94
   3 !   29.4   0.0   7.6e-10   4.9e-07       1      41 [.     794     834 ..     794     835 .. 0.94
   4 !   36.2   0.0   5.5e-12   3.5e-09       1      42 []     836     877 ..     836     877 .. 0.99
   5 !   42.9   0.0   4.3e-14   2.7e-11       1      42 []     878     919 ..     878     919 .. 0.99
   6 !   41.4   0.0   1.3e-13   8.1e-11       1      42 []     920     961 ..     920     961 .. 0.99
   7 !   35.4   0.0     1e-11   6.6e-09       3      41 ..     964    1002 ..     962    1003 .. 0.94
   8 !   42.2   0.0   7.3e-14   4.7e-11       1      42 []    1004    1045 ..    1004    1045 .. 0.99
   9 !   30.0   0.0   4.9e-10   3.2e-07       1      41 [.    1046    1086 ..    1046    1087 .. 0.98
  10 !   23.8   0.0   4.4e-08   2.8e-05       1      42 []    1088    1129 ..    1088    1129 .. 0.98

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 1.4e-05
      TPR_10  12 lrqrgrydeAealleealairrrllGpdHP 41 
                 l++ gry+eAe +++++l i++   G +HP
  EEA21505.1 721 LYSDGRYNEAEVFFRDTLHIHQGKNGKNHP 750
                 8999*************************9 PP

  == domain 2  score: 29.6 bits;  conditional E-value: 6.8e-10
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHP 41 
                 t+ s+ NLa ++r++gr+deAe+l  ++++    + G++HP
  EEA21505.1 752 TLVSMANLASTYRNQGRWDEAEKLEVQVMEKSMTVRGAEHP 792
                 789**************************999999999998 PP

  == domain 3  score: 29.4 bits;  conditional E-value: 7.6e-10
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHP 41 
                 t++s+ NLa +++++gr++eAe+l  ++++    + G++HP
  EEA21505.1 794 TLNSMMNLASTYWNQGRWNEAEKLEVQVMEKSMTVRGAEHP 834
                 89***************************999999999998 PP

  == domain 4  score: 36.2 bits;  conditional E-value: 5.5e-12
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t++s+ NLa +++++gr++eAe+l  ++++    llG++HPd
  EEA21505.1 836 TLNSMMNLASTYWNQGRWNEAEKLEVQVMEKSMTLLGAEHPD 877
                 89***************************************9 PP

  == domain 5  score: 42.9 bits;  conditional E-value: 4.3e-14
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t++s+ NLa +++++gr++eAe+l  ++++i   +lG++HPd
  EEA21505.1 878 TLTSMMNLASTYQSQGRWNEAEKLEVQVMEISTTVLGAEHPD 919
                 89***************************************9 PP

  == domain 6  score: 41.4 bits;  conditional E-value: 1.3e-13
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t++s  NLa ++r++gr++eAe+l  +++++  ++lG++HPd
  EEA21505.1 920 TLTSIANLASTYRNQGRWNEAEKLGVQVIETSTAVLGAEHPD 961
                 89***************************************9 PP

  == domain 7  score: 35.4 bits;  conditional E-value: 1e-11
      TPR_10    3 sslnNLanalrqrgrydeAealleealairrrllGpdHP 41  
                    + NLa ++r++gr++eAe+l  +++++   +lG++HP
  EEA21505.1  964 IRMGNLASTYRNQGRWNEAEKLGVQVIETSTTVLGAEHP 1002
                  5699**********************************9 PP

  == domain 8  score: 42.2 bits;  conditional E-value: 7.3e-14
      TPR_10    1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42  
                  t++s+ NLa +++++gr++eAe+l  ++++i   +lG++HPd
  EEA21505.1 1004 TLTSMANLASTYQSQGRWNEAEKLDMQVMEISITVLGAEHPD 1045
                  89***************************************9 PP

  == domain 9  score: 30.0 bits;  conditional E-value: 4.9e-10
      TPR_10    1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHP 41  
                  t++s  N+a ++r++gr++eAe+l  ++++    +lG++HP
  EEA21505.1 1046 TLASIANMASTYRNQGRWNEAEKLEAQVMEKSMSVLGAEHP 1086
                  899*************************************9 PP

  == domain 10  score: 23.8 bits;  conditional E-value: 4.4e-08
      TPR_10    1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42  
                  t++s++ La +  + g+ ++A  l+ ++++++r+ lGpdHP+
  EEA21505.1 1088 TLTSMTILAFTWKDIGKQQDAILLMSQCIQLCRKYLGPDHPN 1129
                  89***************************************5 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.3   0.0   2.6e-14   1.6e-11       7      71 ..     715     779 ..     710     783 .. 0.92
   2 !   21.4   0.0   3.5e-07   0.00023      36      71 ..     786     821 ..     777     824 .. 0.86
   3 !   42.6   0.0   8.9e-14   5.7e-11       4      71 ..     796     863 ..     793     866 .. 0.92
   4 !   47.6   0.0   2.4e-15   1.6e-12       4      74 ..     838     908 ..     835     911 .. 0.93
   5 !   50.0   0.0   4.3e-16   2.8e-13       2      73 ..     878     949 ..     877     953 .. 0.93
   6 !   48.1   0.0   1.6e-15     1e-12       4      72 ..     922     990 ..     919     994 .. 0.91
   7 !   51.2   0.0   1.7e-16   1.1e-13       7      74 ..     967    1034 ..     961    1037 .. 0.95
   8 !   51.7   0.1   1.2e-16   7.7e-14       5      73 ..    1007    1075 ..    1003    1076 .. 0.93
   9 !   32.4   0.0   1.3e-10   8.5e-08       2      77 .]    1047    1121 ..    1045    1121 .. 0.95
  10 !   13.8   0.0   8.3e-05     0.053      20      51 ..    1106    1137 ..    1101    1142 .. 0.91

  Alignments for each domain:
  == domain 1  score: 44.3 bits;  conditional E-value: 2.6e-14
      TPR_12   7 nnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleea 71 
                  +++a+l+  gry eA+ +++  l i++   G++hp t+ ++ nL+ +yr +gr++eA++l  ++
  EEA21505.1 715 ERIGACLYSDGRYNEAEVFFRDTLHIHQGKNGKNHPSTLVSMANLASTYRNQGRWDEAEKLEVQV 779
                 489********************************************************987665 PP

  == domain 2  score: 21.4 bits;  conditional E-value: 3.5e-07
      TPR_12  36 llGpdhpltattlrnLgrlyralgryeeAlelleea 71 
                 + G +hp+t++++ nL+ +y+ +gr+ eA++l  ++
  EEA21505.1 786 VRGAEHPNTLNSMMNLASTYWNQGRWNEAEKLEVQV 821
                 679***************************986655 PP

  == domain 3  score: 42.6 bits;  conditional E-value: 8.9e-14
      TPR_12   4 talnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleea 71 
                 +++ nla++++ +gr+ eA++l  +++e    + G +hp+t++++ nL+ +y+ +gr+ eA++l  ++
  EEA21505.1 796 NSMMNLASTYWNQGRWNEAEKLEVQVMEKSMTVRGAEHPNTLNSMMNLASTYWNQGRWNEAEKLEVQV 863
                 5555**********************************************************986655 PP

  == domain 4  score: 47.6 bits;  conditional E-value: 2.4e-15
      TPR_12   4 talnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealai 74 
                 +++ nla++++ +gr+ eA++l  +++e    llG +hp+t+t++ nL+ +y+ +gr+ eA++l  ++++i
  EEA21505.1 838 NSMMNLASTYWNQGRWNEAEKLEVQVMEKSMTLLGAEHPDTLTSMMNLASTYQSQGRWNEAEKLEVQVMEI 908
                 5555************************************************************9999988 PP

  == domain 5  score: 50.0 bits;  conditional E-value: 4.3e-16
      TPR_12   2 vatalnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleeala 73 
                 ++t++ nla++++ +gr+ eA++l  +++ei + +lG +hp+t+t+  nL+ +yr +gr+ eA++l  ++++
  EEA21505.1 878 TLTSMMNLASTYQSQGRWNEAEKLEVQVMEISTTVLGAEHPDTLTSIANLASTYRNQGRWNEAEKLGVQVIE 949
                 677778**********************************************************99877766 PP

  == domain 6  score: 48.1 bits;  conditional E-value: 1.6e-15
      TPR_12   4 talnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleeal 72 
                 t+  nla+++r +gr+ eA++l  +++e  +++lG +hp+t++ + nL+ +yr +gr+ eA++l  +++
  EEA21505.1 922 TSIANLASTYRNQGRWNEAEKLGVQVIETSTAVLGAEHPDTLIRMGNLASTYRNQGRWNEAEKLGVQVI 990
                 44449*********************************************************9977766 PP

  == domain 7  score: 51.2 bits;  conditional E-value: 1.7e-16
      TPR_12    7 nnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealai 74  
                   nla+++r +gr+ eA++l  +++e  + +lG +hp t+t++ nL+ +y+ +gr+ eA++l  ++++i
  EEA21505.1  967 GNLASTYRNQGRWNEAEKLGVQVIETSTTVLGAEHPTTLTSMANLASTYQSQGRWNEAEKLDMQVMEI 1034
                  49***********************************************************9999987 PP

  == domain 8  score: 51.7 bits;  conditional E-value: 1.2e-16
      TPR_12    5 alnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleeala 73  
                  ++ nla++++ +gr+ eA++l  +++ei   +lG +hp+t+++  n++ +yr +gr+ eA++l  ++++
  EEA21505.1 1007 SMANLASTYQSQGRWNEAEKLDMQVMEISITVLGAEHPDTLASIANMASTYRNQGRWNEAEKLEAQVME 1075
                  4449**********************************************************9998875 PP

  == domain 9  score: 32.4 bits;  conditional E-value: 1.3e-10
      TPR_12    2 vatalnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiaek 77  
                  +a+++ n+a+++r +gr+ eA++l  +++e   ++lG +hp t+t++  L+ +    g++++A+ l  +++++++k
  EEA21505.1 1047 LASIA-NMASTYRNQGRWNEAEKLEAQVMEKSMSVLGAEHPSTLTSMTILAFTWKDIGKQQDAILLMSQCIQLCRK 1121
                  46777.***********************************************8899***************9986 PP

  == domain 10  score: 13.8 bits;  conditional E-value: 8.3e-05
      TPR_12   20 deAlellekaleiarrllGpdhpltattlrnL 51  
                  ++A+ l  ++++++r++lGpdhp+t+++ r+L
  EEA21505.1 1106 QDAILLMSQCIQLCRKYLGPDHPNTISSIRAL 1137
                  6899999*******************998876 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0         2   1.3e+03       7      30 ..     719     742 ..     715     748 .. 0.72
   2 !   16.2   0.0   1.2e-05    0.0077       2      21 ..     756     775 ..     755     787 .. 0.85
   3 !   10.8   0.0   0.00062       0.4       3      21 ..     799     817 ..     797     829 .. 0.85
   4 !   10.6   0.0   0.00071      0.46       3      21 ..     841     859 ..     839     869 .. 0.88
   5 !   12.0   0.0   0.00026      0.17       3      21 ..     883     901 ..     881     914 .. 0.90
   6 !   13.4   0.0   9.1e-05     0.058       2      21 ..     924     943 ..     923     956 .. 0.90
   7 !   12.3   0.0   0.00021      0.13       3      21 ..     967     985 ..     966     996 .. 0.91
   8 !   13.0   0.0   0.00013     0.082       2      21 ..    1008    1027 ..    1007    1038 .. 0.89
   9 !   13.0   0.0   0.00012     0.079       2      23 ..    1050    1071 ..    1049    1081 .. 0.82

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 2
       TPR_7   7 rlysrlGdyeeAielyeqsLaltk 30 
                  +  ++G+y eA+ +++  L ++ 
  EEA21505.1 719 ACLYSDGRYNEAEVFFRDTLHIHQ 742
                 555667*******99998666655 PP

  == domain 2  score: 16.2 bits;  conditional E-value: 1.2e-05
       TPR_7   2 LlnLarlysrlGdyeeAiel 21 
                   nLa++y+++G+++eA++l
  EEA21505.1 756 MANLASTYRNQGRWDEAEKL 775
                 57***************987 PP

  == domain 3  score: 10.8 bits;  conditional E-value: 0.00062
       TPR_7   3 lnLarlysrlGdyeeAiel 21 
                  nLa++y ++G++ eA++l
  EEA21505.1 799 MNLASTYWNQGRWNEAEKL 817
                 59**************987 PP

  == domain 4  score: 10.6 bits;  conditional E-value: 0.00071
       TPR_7   3 lnLarlysrlGdyeeAiel 21 
                  nLa++y ++G++ eA++l
  EEA21505.1 841 MNLASTYWNQGRWNEAEKL 859
                 59**************986 PP

  == domain 5  score: 12.0 bits;  conditional E-value: 0.00026
       TPR_7   3 lnLarlysrlGdyeeAiel 21 
                  nLa++y+++G++ eA++l
  EEA21505.1 883 MNLASTYQSQGRWNEAEKL 901
                 59**************986 PP

  == domain 6  score: 13.4 bits;  conditional E-value: 9.1e-05
       TPR_7   2 LlnLarlysrlGdyeeAiel 21 
                 + nLa++y+++G++ eA++l
  EEA21505.1 924 IANLASTYRNQGRWNEAEKL 943
                 78***************986 PP

  == domain 7  score: 12.3 bits;  conditional E-value: 0.00021
       TPR_7   3 lnLarlysrlGdyeeAiel 21 
                  nLa++y+++G++ eA++l
  EEA21505.1 967 GNLASTYRNQGRWNEAEKL 985
                 69**************986 PP

  == domain 8  score: 13.0 bits;  conditional E-value: 0.00013
       TPR_7    2 LlnLarlysrlGdyeeAiel 21  
                    nLa++y+++G++ eA++l
  EEA21505.1 1008 MANLASTYQSQGRWNEAEKL 1027
                  57***************987 PP

  == domain 9  score: 13.0 bits;  conditional E-value: 0.00012
       TPR_7    2 LlnLarlysrlGdyeeAielye 23  
                  + n+a++y+++G++ eA++l  
  EEA21505.1 1050 IANMASTYRNQGRWNEAEKLEA 1071
                  78***************99855 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   0.0    0.0052       3.4       4      25 ..     714     735 ..     711     741 .. 0.86
   2 !    9.2   0.0    0.0022       1.4       5      22 ..     757     774 ..     755     775 .. 0.90
   3 !    8.0   0.0    0.0055       3.5       5      22 ..     799     816 ..     796     817 .. 0.90
   4 !    8.0   0.0    0.0055       3.5       5      22 ..     841     858 ..     838     859 .. 0.90
   5 ?    6.3   0.0     0.019        12       5      22 ..     883     900 ..     880     901 .. 0.90
   6 !    8.3   0.0    0.0042       2.7       6      24 ..     926     944 ..     923     950 .. 0.85
   7 !    8.2   0.0    0.0047         3       6      26 ..     968     988 ..     966     993 .. 0.85
   8 ?    5.8   0.0     0.028        18       5      22 ..    1009    1026 ..    1006    1027 .. 0.90
   9 ?    5.9   0.0     0.025        16       6      22 ..    1052    1068 ..    1049    1069 .. 0.90
  10 ?   -0.1   0.0       2.1   1.4e+03       8      33 ..    1096    1121 ..    1093    1122 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0052
       TPR_2   4 lynlGlayyklgdyeeAleafe 25 
                   ++G ++y  g+y+eA+ +f+
  EEA21505.1 714 MERIGACLYSDGRYNEAEVFFR 735
                 5689*************99997 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.0022
       TPR_2   5 ynlGlayyklgdyeeAle 22 
                  nl+  y+++g+++eA++
  EEA21505.1 757 ANLASTYRNQGRWDEAEK 774
                 589*************98 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.0055
       TPR_2   5 ynlGlayyklgdyeeAle 22 
                 +nl+  y+++g+++eA++
  EEA21505.1 799 MNLASTYWNQGRWNEAEK 816
                 79**************98 PP

  == domain 4  score: 8.0 bits;  conditional E-value: 0.0055
       TPR_2   5 ynlGlayyklgdyeeAle 22 
                 +nl+  y+++g+++eA++
  EEA21505.1 841 MNLASTYWNQGRWNEAEK 858
                 79**************98 PP

  == domain 5  score: 6.3 bits;  conditional E-value: 0.019
       TPR_2   5 ynlGlayyklgdyeeAle 22 
                 +nl+  y  +g+++eA++
  EEA21505.1 883 MNLASTYQSQGRWNEAEK 900
                 79**************98 PP

  == domain 6  score: 8.3 bits;  conditional E-value: 0.0042
       TPR_2   6 nlGlayyklgdyeeAleaf 24 
                 nl+  y+++g+++eA+++ 
  EEA21505.1 926 NLASTYRNQGRWNEAEKLG 944
                 89*************9975 PP

  == domain 7  score: 8.2 bits;  conditional E-value: 0.0047
       TPR_2   6 nlGlayyklgdyeeAleafek 26 
                 nl+  y+++g+++eA+++  +
  EEA21505.1 968 NLASTYRNQGRWNEAEKLGVQ 988
                 899************997555 PP

  == domain 8  score: 5.8 bits;  conditional E-value: 0.028
       TPR_2    5 ynlGlayyklgdyeeAle 22  
                   nl+  y  +g+++eA++
  EEA21505.1 1009 ANLASTYQSQGRWNEAEK 1026
                  699*************98 PP

  == domain 9  score: 5.9 bits;  conditional E-value: 0.025
       TPR_2    6 nlGlayyklgdyeeAle 22  
                  n++  y+++g+++eA++
  EEA21505.1 1052 NMASTYRNQGRWNEAEK 1068
                  78999**********98 PP

  == domain 10  score: -0.1 bits;  conditional E-value: 2.1
       TPR_2    8 GlayyklgdyeeAleafekAleldPn 33  
                  +  +   g+ ++A+ ++ ++++l+ +
  EEA21505.1 1096 AFTWKDIGKQQDAILLMSQCIQLCRK 1121
                  6666777999************9875 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.4   0.0    0.0015      0.96       6      28 ..     716     738 ..     713     743 .. 0.88
   2 !    9.4   0.0    0.0014      0.91       6      22 ..     758     774 ..     755     775 .. 0.92
   3 !    7.1   0.0    0.0078         5       5      22 ..     799     816 ..     796     817 .. 0.91
   4 !    7.1   0.0    0.0078         5       5      22 ..     841     858 ..     838     859 .. 0.91
   5 !    7.9   0.0    0.0045       2.9       5      22 ..     883     900 ..     881     901 .. 0.92
   6 !    7.5   0.0    0.0061       3.9       6      22 ..     926     942 ..     923     943 .. 0.93
   7 !    7.5   0.0    0.0059       3.8       6      22 ..     968     984 ..     966     985 .. 0.93
   8 !    7.5   0.0    0.0061       3.9       6      22 ..    1010    1026 ..    1007    1027 .. 0.92
   9 ?    6.4   0.0     0.013       8.6       6      22 ..    1052    1068 ..    1049    1069 .. 0.92

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0015
                 HHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_1   6 nlGnayfklgkydeAleyyekAL 28 
                 ++G+++++ g+y+eA+ +++  L
  EEA21505.1 716 RIGACLYSDGRYNEAEVFFRDTL 738
                 79****************98665 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.0014
                 HHHHHHHHTT-HHHHHH CS
       TPR_1   6 nlGnayfklgkydeAle 22 
                 nl+ +y+++g++deA++
  EEA21505.1 758 NLASTYRNQGRWDEAEK 774
                 9**************97 PP

  == domain 3  score: 7.1 bits;  conditional E-value: 0.0078
                 HHHHHHHHHTT-HHHHHH CS
       TPR_1   5 ynlGnayfklgkydeAle 22 
                  nl+ +y ++g+++eA++
  EEA21505.1 799 MNLASTYWNQGRWNEAEK 816
                 7***************97 PP

  == domain 4  score: 7.1 bits;  conditional E-value: 0.0078
                 HHHHHHHHHTT-HHHHHH CS
       TPR_1   5 ynlGnayfklgkydeAle 22 
                  nl+ +y ++g+++eA++
  EEA21505.1 841 MNLASTYWNQGRWNEAEK 858
                 7***************97 PP

  == domain 5  score: 7.9 bits;  conditional E-value: 0.0045
                 HHHHHHHHHTT-HHHHHH CS
       TPR_1   5 ynlGnayfklgkydeAle 22 
                  nl+ +y+++g+++eA++
  EEA21505.1 883 MNLASTYQSQGRWNEAEK 900
                 69**************97 PP

  == domain 6  score: 7.5 bits;  conditional E-value: 0.0061
                 HHHHHHHHTT-HHHHHH CS
       TPR_1   6 nlGnayfklgkydeAle 22 
                 nl+ +y+++g+++eA++
  EEA21505.1 926 NLASTYRNQGRWNEAEK 942
                 9**************97 PP

  == domain 7  score: 7.5 bits;  conditional E-value: 0.0059
                 HHHHHHHHTT-HHHHHH CS
       TPR_1   6 nlGnayfklgkydeAle 22 
                 nl+ +y+++g+++eA++
  EEA21505.1 968 NLASTYRNQGRWNEAEK 984
                 9**************97 PP

  == domain 8  score: 7.5 bits;  conditional E-value: 0.0061
                  HHHHHHHHTT-HHHHHH CS
       TPR_1    6 nlGnayfklgkydeAle 22  
                  nl+ +y+++g+++eA++
  EEA21505.1 1010 NLASTYQSQGRWNEAEK 1026
                  9**************97 PP

  == domain 9  score: 6.4 bits;  conditional E-value: 0.013
                  HHHHHHHHTT-HHHHHH CS
       TPR_1    6 nlGnayfklgkydeAle 22  
                  n++ +y+++g+++eA++
  EEA21505.1 1052 NMASTYRNQGRWNEAEK 1068
                  99*************97 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.0      0.87   5.5e+02      31      48 ..     717     734 ..     694     743 .. 0.77
   2 !    8.7   0.0    0.0039       2.5       2      47 ..     722     775 ..     721     783 .. 0.77
   3 !    8.7   0.0    0.0038       2.4      19      47 ..     789     817 ..     777     825 .. 0.88
   4 !    8.7   0.0    0.0038       2.4      19      47 ..     831     859 ..     819     867 .. 0.88
   5 ?    5.6   0.0     0.035        23      19      47 ..     873     901 ..     861     908 .. 0.87
   6 ?    5.5   0.0     0.038        24      19      47 ..     915     943 ..     906     944 .. 0.89
   7 ?    3.5   0.0      0.16     1e+02      29      47 ..     966     985 ..     952     991 .. 0.81
   8 ?    3.3   0.0      0.18   1.2e+02      23      47 ..    1003    1027 ..     995    1033 .. 0.83
   9 !    7.8   0.0    0.0075       4.8      19      53 ..    1041    1075 ..    1037    1078 .. 0.88

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.87
      TPR_19  31 LAeallalgqldeAealL 48 
                    +l++ g+++eAe   
  EEA21505.1 717 IGACLYSDGRYNEAEVFF 734
                 567999999999999875 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.0039
      TPR_19   2 laegdyaeAlalleqalqe........dpknaearllLAeallalgqldeAeal 47 
                 + +g+y eA  +++  l           p  +   ++LA  + ++g++deAe+l
  EEA21505.1 722 YSDGRYNEAEVFFRDTLHIhqgkngknHPSTLVSMANLASTYRNQGRWDEAEKL 775
                 6789999999999999966555544334445555669***************86 PP

  == domain 3  score: 8.7 bits;  conditional E-value: 0.0038
      TPR_19  19 qedpknaearllLAeallalgqldeAeal 47 
                 +e p+ ++  ++LA  ++++g+++eAe+l
  EEA21505.1 789 AEHPNTLNSMMNLASTYWNQGRWNEAEKL 817
                 6789999999*****************86 PP

  == domain 4  score: 8.7 bits;  conditional E-value: 0.0038
      TPR_19  19 qedpknaearllLAeallalgqldeAeal 47 
                 +e p+ ++  ++LA  ++++g+++eAe+l
  EEA21505.1 831 AEHPNTLNSMMNLASTYWNQGRWNEAEKL 859
                 6789999999*****************86 PP

  == domain 5  score: 5.6 bits;  conditional E-value: 0.035
      TPR_19  19 qedpknaearllLAeallalgqldeAeal 47 
                 +e p+ +   ++LA  + ++g+++eAe+l
  EEA21505.1 873 AEHPDTLTSMMNLASTYQSQGRWNEAEKL 901
                 67899999999***************986 PP

  == domain 6  score: 5.5 bits;  conditional E-value: 0.038
      TPR_19  19 qedpknaearllLAeallalgqldeAeal 47 
                 +e p+ +   ++LA  + ++g+++eAe+l
  EEA21505.1 915 AEHPDTLTSIANLASTYRNQGRWNEAEKL 943
                 678888889999**************985 PP

  == domain 7  score: 3.5 bits;  conditional E-value: 0.16
      TPR_19  29 l.lLAeallalgqldeAeal 47 
                 + +LA  + ++g+++eAe+l
  EEA21505.1 966 MgNLASTYRNQGRWNEAEKL 985
                 3479*************986 PP

  == domain 8  score: 3.3 bits;  conditional E-value: 0.18
      TPR_19   23 knaearllLAeallalgqldeAeal 47  
                    +   ++LA  + ++g+++eAe+l
  EEA21505.1 1003 TTLTSMANLASTYQSQGRWNEAEKL 1027
                  555566789*************986 PP

  == domain 9  score: 7.8 bits;  conditional E-value: 0.0075
      TPR_19   19 qedpknaearllLAeallalgqldeAealLdalpe 53  
                  +e p+ ++  +++A  + ++g+++eAe+l ++++e
  EEA21505.1 1041 AEHPDTLASIANMASTYRNQGRWNEAEKLEAQVME 1075
                  6889999999*****************99777766 PP

>> TPR_MalT  MalT-like TPR region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.4   7.5e-08   4.8e-05      53     184 ..     724     860 ..     711     870 .. 0.82
   2 !   11.0   0.3   0.00031       0.2      42     109 ..     839     908 ..     826     915 .. 0.77
   3 !   32.9   1.8   6.7e-11   4.3e-08      40     183 ..     879    1027 ..     870    1035 .. 0.88
   4 ?    2.2   0.1      0.15        94      42     116 ..    1049    1125 ..    1040    1133 .. 0.70

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 7.5e-08
    TPR_MalT  53 qGdleaAlqalqeaekl..arqadslhvallallqqaeilvaqGrLheAletyeqalqlateqglqqlplvgfllvlladllyEwndLeeAeqhlqeGi 149
                 +G+ ++A+  ++ + ++   ++ ++ + +l+++  +a +++ qGr +eA+++  q ++   + ++++ p     +  la  ++ +++  eAe+   + +
  EEA21505.1 724 DGRYNEAEVFFRDTLHIhqGKNGKNHPSTLVSMANLASTYRNQGRWDEAEKLEVQVMEKSMTVRGAEHPNTLNSMMNLASTYWNQGRWNEAEKLEVQVM 822
                 67888899999988876234667777889****************************999999999999777777899**************9888888 PP

    TPR_MalT 150 e..lleql.epeaaldayvllarialaqGdleeAetll 184
                 e  ++ ++ e   +l + + la  ++ qG++ eAe+l 
  EEA21505.1 823 EksMTVRGaEHPNTLNSMMNLASTYWNQGRWNEAEKLE 860
                 8443333336678999******************9985 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 0.00031
    TPR_MalT  42 atavlGeasllqGdleaAlqalqeae...klarqadslhvallallqqaeilvaqGrLheAletyeqalql 109
                  +++l+ +++ qG+ ++A++   ++    +++++a++++ +l++++ +a +++ qGr  eA+++  q ++ 
  EEA21505.1 839 SMMNLASTYWNQGRWNEAEKLEVQVMeksMTLLGAEHPD-TLTSMMNLASTYQSQGRWNEAEKLEVQVMEI 908
                 57899999*****99999987554431114467777777.9*******************99987777665 PP

  == domain 3  score: 32.9 bits;  conditional E-value: 6.7e-11
    TPR_MalT   40 iaatavlGeasllqGdleaAlqalq...eaeklarqadslhvallallqqaeilvaqGrLheAletyeqalqlateqglqqlplvgfllvlladlly 133 
                  ++ +++l+ +++ qG+ ++A++      e++++ ++a++++ +l+++  +a +++ qGr  eA+++  q ++  t   +++ p   + +  la  ++
  EEA21505.1  879 LTSMMNLASTYQSQGRWNEAEKLEVqvmEISTTVLGAEHPD-TLTSIANLASTYRNQGRWNEAEKLGVQVIETSTAVLGAEHPDTLIRMGNLASTYR 974 
                  56678999************997551225566678888887.********************************************999******** PP

    TPR_MalT  134 EwndLeeAeqhlqeGielleql...epeaaldayvllarialaqGdleeAetl 183 
                   +++  eAe+   + ie +  +   e  ++l + + la  +++qG++ eAe+l
  EEA21505.1  975 NQGRWNEAEKLGVQVIETSTTVlgaEHPTTLTSMANLASTYQSQGRWNEAEKL 1027
                  *****************999976544567889******************997 PP

  == domain 4  score: 2.2 bits;  conditional E-value: 0.15
    TPR_MalT   42 atavlGeasllqGdleaAlqalqeae.kla..rqadslhvallallqqaeilvaqGrLheAletyeqalqlateqglq 116 
                    a+++ ++  qG+ ++A++  +++  k +  ++a+++  +l++++ +a +    G+ ++A+ ++ q +ql ++  ++
  EEA21505.1 1049 SIANMASTYRNQGRWNEAEKLEAQVMeKSMsvLGAEHPS-TLTSMTILAFTWKDIGKQQDAILLMSQCIQLCRKYLGP 1125
                  456788888888888888887776652333014444444.78888888888888888888888888888888776665 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.0   0.00063       0.4      14      34 .]     754     774 ..     747     774 .. 0.86
   2 ?    3.0   0.1      0.26   1.7e+02      10      34 .]     792     816 ..     789     816 .. 0.86
   3 ?    3.0   0.1      0.26   1.7e+02      10      34 .]     834     858 ..     831     858 .. 0.86
   4 ?    6.1   0.0     0.026        17      15      34 .]     881     900 ..     874     900 .. 0.89
   5 ?    6.6   0.0     0.019        12      16      34 .]     924     942 ..     917     942 .. 0.89
   6 ?    5.7   0.1     0.036        23      18      34 .]     968     984 ..     966     984 .. 0.91
   7 ?    6.6   0.0     0.018        11      14      34 .]    1006    1026 ..    1000    1026 .. 0.89
   8 ?    4.3   0.0       0.1        64      17      34 .]    1051    1068 ..    1044    1068 .. 0.91
   9 ?    0.0   0.0       2.3   1.5e+03      16      33 ..    1092    1109 ..    1089    1109 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00063
      TPR_17  14 daynnLAelllknGdlmtArq 34 
                 +++ nLA +++++G++++A++
  EEA21505.1 754 VSMANLASTYRNQGRWDEAEK 774
                 799****************86 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.26
      TPR_17  10 PnnadaynnLAelllknGdlmtArq 34 
                 Pn  +++ nLA ++ ++G++ +A++
  EEA21505.1 792 PNTLNSMMNLASTYWNQGRWNEAEK 816
                 666789**************99985 PP

  == domain 3  score: 3.0 bits;  conditional E-value: 0.26
      TPR_17  10 PnnadaynnLAelllknGdlmtArq 34 
                 Pn  +++ nLA ++ ++G++ +A++
  EEA21505.1 834 PNTLNSMMNLASTYWNQGRWNEAEK 858
                 666789**************99985 PP

  == domain 4  score: 6.1 bits;  conditional E-value: 0.026
      TPR_17  15 aynnLAelllknGdlmtArq 34 
                 ++ nLA ++ ++G++ +A++
  EEA21505.1 881 SMMNLASTYQSQGRWNEAEK 900
                 799**************985 PP

  == domain 5  score: 6.6 bits;  conditional E-value: 0.019
      TPR_17  16 ynnLAelllknGdlmtArq 34 
                   nLA +++++G++ +A++
  EEA21505.1 924 IANLASTYRNQGRWNEAEK 942
                 57**************985 PP

  == domain 6  score: 5.7 bits;  conditional E-value: 0.036
      TPR_17  18 nLAelllknGdlmtArq 34 
                 nLA +++++G++ +A++
  EEA21505.1 968 NLASTYRNQGRWNEAEK 984
                 9*************985 PP

  == domain 7  score: 6.6 bits;  conditional E-value: 0.018
      TPR_17   14 daynnLAelllknGdlmtArq 34  
                   ++ nLA ++ ++G++ +A++
  EEA21505.1 1006 TSMANLASTYQSQGRWNEAEK 1026
                  5899**************985 PP

  == domain 8  score: 4.3 bits;  conditional E-value: 0.1
      TPR_17   17 nnLAelllknGdlmtArq 34  
                   n+A +++++G++ +A++
  EEA21505.1 1051 ANMASTYRNQGRWNEAEK 1068
                  69*************985 PP

  == domain 9  score: 0.0 bits;  conditional E-value: 2.3
      TPR_17   16 ynnLAelllknGdlmtAr 33  
                  ++ LA +++ +G+ ++A+
  EEA21505.1 1092 MTILAFTWKDIGKQQDAI 1109
                  6679***********996 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0      0.88   5.7e+02      38      59 ..     715     736 ..     712     750 .. 0.84
   2 ?    3.7   0.0      0.15        97       2      19 ..     758     775 ..     757     779 .. 0.83
   3 ?    5.4   0.0     0.047        30      28      55 ..     789     816 ..     785     823 .. 0.73
   4 ?    5.4   0.0     0.045        29      28      55 ..     831     858 ..     827     866 .. 0.73
   5 ?    3.4   0.0       0.2   1.3e+02      28      55 ..     873     900 ..     869     906 .. 0.81
   6 ?    1.3   0.0      0.85   5.5e+02       2      19 ..     926     943 ..     925     947 .. 0.89
   7 ?    1.0   0.0       1.1   7.2e+02       3      19 ..     969     985 ..     958     988 .. 0.89
   8 ?   -0.2   0.0       2.5   1.6e+03       2      19 ..    1010    1027 ..    1009    1027 .. 0.89
   9 ?    0.4   0.1       1.7   1.1e+03       2      19 ..    1052    1069 ..    1051    1072 .. 0.87

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.88
      TPR_16  38 lllgdaalrqgrlaeAaalyra 59 
                    g +++  gr+ eA+ ++r 
  EEA21505.1 715 ERIGACLYSDGRYNEAEVFFRD 736
                 56799***********999987 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.15
      TPR_16   2 alaraalragdyddAaaa 19 
                 +la  ++++g++d+A+++
  EEA21505.1 758 NLASTYRNQGRWDEAEKL 775
                 678889999999999875 PP

  == domain 3  score: 5.4 bits;  conditional E-value: 0.047
      TPR_16  28 pssPdaaeAllllgdaalrqgrlaeAaa 55 
                 +++P +  ++++l+  ++ qgr+ eA+ 
  EEA21505.1 789 AEHPNTLNSMMNLASTYWNQGRWNEAEK 816
                 5667777778888888888888888773 PP

  == domain 4  score: 5.4 bits;  conditional E-value: 0.045
      TPR_16  28 pssPdaaeAllllgdaalrqgrlaeAaa 55 
                 +++P +  ++++l+  ++ qgr+ eA+ 
  EEA21505.1 831 AEHPNTLNSMMNLASTYWNQGRWNEAEK 858
                 5667777788888888888888888873 PP

  == domain 5  score: 3.4 bits;  conditional E-value: 0.2
      TPR_16  28 pssPdaaeAllllgdaalrqgrlaeAaa 55 
                 +++Pd+  ++++l+  +  qgr+ eA+ 
  EEA21505.1 873 AEHPDTLTSMMNLASTYQSQGRWNEAEK 900
                 6779999999999999999999999984 PP

  == domain 6  score: 1.3 bits;  conditional E-value: 0.85
      TPR_16   2 alaraalragdyddAaaa 19 
                 +la  ++++g++ +A+++
  EEA21505.1 926 NLASTYRNQGRWNEAEKL 943
                 689999*********985 PP

  == domain 7  score: 1.0 bits;  conditional E-value: 1.1
      TPR_16   3 laraalragdyddAaaa 19 
                 la  ++++g++ +A+++
  EEA21505.1 969 LASTYRNQGRWNEAEKL 985
                 78889999999999975 PP

  == domain 8  score: -0.2 bits;  conditional E-value: 2.5
      TPR_16    2 alaraalragdyddAaaa 19  
                  +la  +  +g++ +A+++
  EEA21505.1 1010 NLASTYQSQGRWNEAEKL 1027
                  68999**********985 PP

  == domain 9  score: 0.4 bits;  conditional E-value: 1.7
      TPR_16    2 alaraalragdyddAaaa 19  
                  ++a  ++++g++ +A+++
  EEA21505.1 1052 NMASTYRNQGRWNEAEKL 1069
                  578899*********985 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0       1.1   7.3e+02       6      25 ..     716     735 ..     711     736 .. 0.83
   2 ?    4.6   0.0     0.071        45       4      22 ..     756     774 ..     754     775 .. 0.90
   3 ?    5.8   0.1     0.029        19       3      22 ..     797     816 ..     795     817 .. 0.88
   4 ?    5.8   0.1     0.029        19       3      22 ..     839     858 ..     837     859 .. 0.88
   5 ?    3.6   0.0      0.15        95       3      22 ..     881     900 ..     879     907 .. 0.90
   6 ?    3.4   0.0      0.18   1.1e+02       4      22 ..     924     942 ..     921     947 .. 0.88
   7 ?    2.6   0.0      0.31     2e+02       5      22 ..     967     984 ..     965     988 .. 0.90
   8 ?    3.9   0.0      0.12        75       3      22 ..    1007    1026 ..    1005    1035 .. 0.83
   9 ?    1.5   0.0      0.68   4.3e+02       5      22 ..    1051    1068 ..    1047    1069 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 1.1
                 HHHHHHHHTT-HHHHHHHHH CS
       TPR_8   6 nlgsiylklgdyeeAkeyye 25 
                 ++g ++ + g+y+eA+ +++
  EEA21505.1 716 RIGACLYSDGRYNEAEVFFR 735
                 688889999*******9987 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.071
                 HHHHHHHHHHTT-HHHHHH CS
       TPR_8   4 yynlgsiylklgdyeeAke 22 
                 + nl+s+y+++g+ +eA++
  EEA21505.1 756 MANLASTYRNQGRWDEAEK 774
                 689**********999986 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.029
                 HHHHHHHHHHHTT-HHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAke 22 
                 +++nl+s+y+++g+ +eA++
  EEA21505.1 797 SMMNLASTYWNQGRWNEAEK 816
                 789***********999986 PP

  == domain 4  score: 5.8 bits;  conditional E-value: 0.029
                 HHHHHHHHHHHTT-HHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAke 22 
                 +++nl+s+y+++g+ +eA++
  EEA21505.1 839 SMMNLASTYWNQGRWNEAEK 858
                 789***********999986 PP

  == domain 5  score: 3.6 bits;  conditional E-value: 0.15
                 HHHHHHHHHHHTT-HHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAke 22 
                 +++nl+s+y+++g+ +eA++
  EEA21505.1 881 SMMNLASTYQSQGRWNEAEK 900
                 689***********999986 PP

  == domain 6  score: 3.4 bits;  conditional E-value: 0.18
                 HHHHHHHHHHTT-HHHHHH CS
       TPR_8   4 yynlgsiylklgdyeeAke 22 
                   nl+s+y+++g+ +eA++
  EEA21505.1 924 IANLASTYRNQGRWNEAEK 942
                 579**********999986 PP

  == domain 7  score: 2.6 bits;  conditional E-value: 0.31
                 HHHHHHHHHTT-HHHHHH CS
       TPR_8   5 ynlgsiylklgdyeeAke 22 
                  nl+s+y+++g+ +eA++
  EEA21505.1 967 GNLASTYRNQGRWNEAEK 984
                 59**********999986 PP

  == domain 8  score: 3.9 bits;  conditional E-value: 0.12
                  HHHHHHHHHHHTT-HHHHHH CS
       TPR_8    3 ayynlgsiylklgdyeeAke 22  
                  ++ nl+s+y+++g+ +eA++
  EEA21505.1 1007 SMANLASTYQSQGRWNEAEK 1026
                  678***********999987 PP

  == domain 9  score: 1.5 bits;  conditional E-value: 0.68
                  HHHHHHHHHTT-HHHHHH CS
       TPR_8    5 ynlgsiylklgdyeeAke 22  
                   n++s+y+++g+ +eA++
  EEA21505.1 1051 ANMASTYRNQGRWNEAEK 1068
                  799*********999986 PP

>> TPR_5  Tetratrico peptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.4   0.0   0.00044      0.28      13     105 ..     723     826 ..     712     829 .. 0.70
   2 ?    4.4   0.0     0.065        42      39      96 ..     838     901 ..     824     911 .. 0.73
   3 ?    2.3   0.0       0.3   1.9e+02      42      63 ..     925     946 ..     913     962 .. 0.84
   4 ?    3.2   0.0      0.15        98      44      93 ..     969    1024 ..     966    1034 .. 0.62
   5 ?    6.3   0.0     0.017        11      42      96 ..    1051    1111 ..    1005    1120 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00044
       TPR_5  13 stGhedkavplYrraLa..eGLagarrrr...atiqLassLRnlGeaeealaL....LraeleapsdelddalaaflaLv..Lsdlgrereavsivlla 100
                 s G+ ++a+  +r  L+  +G +g +       +  Las+ Rn G+ +ea++L    +++ ++ ++ e  + l++++ L+    ++gr +ea ++ ++ 
  EEA21505.1 723 SDGRYNEAEVFFRDTLHihQGKNGKNHPStlvSMANLASTYRNQGRWDEAEKLevqvMEKSMTVRGAEHPNTLNSMMNLAstYWNQGRWNEAEKLEVQV 821
                 6677888888888877433455554444400055689*************98744436777788999******99987752156899999998877777 PP

       TPR_5 101 laehl 105
                 + + +
  EEA21505.1 822 MEKSM 826
                 66655 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.065
       TPR_5  39 ratiqLassLRnlGeaeealaL....LraeleapsdelddalaaflaLv..Lsdlgrereavsi 96 
                 + ++ Las+  n G+ +ea++L    +++ ++  + e  d l++++ L+    ++gr +ea ++
  EEA21505.1 838 NSMMNLASTYWNQGRWNEAEKLevqvMEKSMTLLGAEHPDTLTSMMNLAstYQSQGRWNEAEKL 901
                 56789*************9988333245555557889999999998775226688888887555 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.3
       TPR_5  42 iqLassLRnlGeaeealaLLra 63 
                   Las+ Rn G+ +ea++L  +
  EEA21505.1 925 ANLASTYRNQGRWNEAEKLGVQ 946
                 579*************999655 PP

  == domain 4  score: 3.2 bits;  conditional E-value: 0.15
       TPR_5   44 LassLRnlGeaeealaLLraelea....psdelddalaaflaL..vLsdlgrerea 93  
                  Las+ Rn G+ +ea++L  + +e+     + e    l++++ L  +  ++gr +ea
  EEA21505.1  969 LASTYRNQGRWNEAEKLGVQVIETsttvLGAEHPTTLTSMANLasTYQSQGRWNEA 1024
                  9************9988555444411114555555565544331145566666666 PP

  == domain 5  score: 6.3 bits;  conditional E-value: 0.017
       TPR_5   42 iqLassLRnlGeaeealaLLraeleap....sdelddalaa..flaLvLsdlgrereavsi 96  
                    +as+ Rn G+ +ea++L  + +e++    + e    l++  +la +  d g++++a+ +
  EEA21505.1 1051 ANMASTYRNQGRWNEAEKLEAQVMEKSmsvlGAEHPSTLTSmtILAFTWKDIGKQQDAILL 1111
                  479**************99777776641111456666665411567777889999988754 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.6   0.0   1.4e-10   9.1e-08       7     182 ..     331     507 ..     325     557 .. 0.77

  Alignments for each domain:
  == domain 1  score: 31.6 bits;  conditional E-value: 1.4e-10
                 HHHHHHHCTTTSCSEEEEEEESTTSSHHHHHHHHCCSHCCCCCCBTEEEEE.EEESXXHHHHHHHXXHHHHHCCCTTSSSS-STTSHHHHHHHHCCCT. CS
      NB-ARC   7 kviekLlekdelqslvvalvGmgGvGKttlakqilnksdevegrFdsvawv.vvsktdkseeiletilkeLslseddleekeeveslkrklvrlLltk. 103
                 ++  +L+ + + + + +al G gG+GKt +a +    +   + +  sv w+ +vs+++ ++  +  i+++L l    + + ++v   k +++ +L +  
  EEA21505.1 331 RLE-NLM-SMSYGPMKIALTGLGGMGKTQIALELAYRMRDGDDKC-SVFWIpSVSQESVEQAYMS-IAQHLRLP---DANPADV---KMRVQSYLSHEr 419
                 544.455.45556669*****************998844444443.7778869999999998888.*****877...4555544...477888887655 PP

                 ..TEEEEEE.....EE-SHHH....H.....HHHHCHTTSEEEEEESBCCCCCCS-S-EEEEEESS--HHHHHHHHHHCCTS-GGCHH.. CS
      NB-ARC 104 ..rfllvlD.....DVweeed....wdkigvvlparenrlrvllTTRdeevanavsatsekievelLekdeawellenkvfekkleekes 182
                   r ll+ D     D w + d    + ++++ lp ++    +l+TTR++++a++ +  s++i ++   ++ a e+l +   + +l ++++
  EEA21505.1 420 agRWLLICDnaddmDMWVSRDrttpLTALSAFLP-QSDHGCILFTTRNRKLAQKLAP-SHVIPLHEVDEETAKEILMQSLLRPELLSETT 507
                 679*****9888888999888889999*******.5555569*********999887.88888888999999998888877777776665 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.6   0.3   3.7e-09   2.3e-06       3     160 ..     345     494 ..     344     562 .. 0.83
   2 ?   -0.7   0.0       1.9   1.2e+03     105     140 ..     642     677 ..     622     686 .. 0.84

  Alignments for each domain:
  == domain 1  score: 27.6 bits;  conditional E-value: 3.7e-09
                 EEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-....-HCHHHCCCCTS--SSS-CCHHHH.CCSCCCEEEEEE-STT-SS-TCH CS
       NACHT   3 vilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgna.rsladllfsqlpepaapvsevwavl.lelperlLlilDglDelvtdlgq 99 
                 ++l+G  G+GKT  + +la  +++g++++     vF++++ + +  ++a +s+a++l+ +   pa+   +v ++l  e++ r Lli D +D++    + 
  EEA21505.1 345 IALTGLGGMGKTQIALELAYRMRDGDDKC----SVFWIPSVSQESVEQAyMSIAQHLRLPDANPADVKMRVQSYLsHERAGRWLLICDNADDMDMWVSR 439
                 68999********************9555....689988877777777779*******9999999999998887735899**************98888 PP

                 .........HHHHHCTTTTT--EEEEEEECCCHHHHCTTSSCE..EEEE--TCCHHHHHHH CS
       NACHT 100 kekqpvrtlLselirkkllpeasllltvrpralrdleeqleeaivlevegfsesrrkqlvr 160
                  +++   t Ls  +++      ++l t+r+r+l   +++l+ ++v+ + +  e+ +k++++
  EEA21505.1 440 -DRTTPLTALSAFLPQ--SDHGCILFTTRNRKL---AQKLAPSHVIPLHEVDEETAKEILM 494
                 .888888888888888..777888888888777...6667666677777777777776665 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 1.9
                 ....HHHHHCTTTTT--EEEEEEECCCHHHHCTTSS CS
       NACHT 105 vrtlLselirkkllpeasllltvrpralrdleeqle 140
                 + + L +l +++ l+++ ll t+  ra   lee + 
  EEA21505.1 642 ILHRLVHLATRSWLRKNALLHTSARRAADSLEEVFP 677
                 5677889999*************9999988888765 PP

>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.1   0.0   8.2e-10   5.2e-07       4     218 ..      15     279 ..      13     299 .. 0.72

  Alignments for each domain:
  == domain 1  score: 29.1 bits;  conditional E-value: 8.2e-10
                 EEESSHHHHHHHHHHEEEEEEEEEE....TTEEEEEEEETTEEEEEEE--...SSHHHHHHHHHHHHHHHC--SEEEEEEEEEES...STTT-TT-EEE CS
   PNP_UDP_1   4 iivgspgevellaespleetpfgre...grgfkfvtGtlkgkpvvivstG...iGkpnaavvaeirllkefgvkaiiriGtaGgl...npdlkvGDvvi 93 
                  i++ p e+++ ++  l+et+   +       ++++G+++ + vvi++      G+++aa         +fg    +++G+ Gg+   ++d+++GDvv+
  EEA21505.1  15 WICALPLEMAAAKAM-LDETHSPLSqppADHNTYTLGSMGDHAVVIACLPygvYGTTSAA--------TMFG----LMVGIGGGVpskHADIRLGDVVV 100
                 578888888888777.33332221123466667778888888888888875655666666........3343....6789*****99999********* PP

                 EEE......EEESSSCCGCCTHHCC.............................................TCCCCTTSSEE--HHHHHHHHH....... CS
   PNP_UDP_1  94 pdd......ainfdgrsplygpkee.............................................gqyfpdsydapadpelrallke....... 134
                 ++       +i++d++ + +g ++e                                                + ++ d  +d+++ +  ++       
  EEA21505.1 101 SKPsatsggVIQYDYGKTVHGGRIErtgslnkphptlltamaniesnrilgkdpiigivhdivkmdeeaqKRFRQPEHDWLFDAAYSHEGHNsdcvacd 199
                 **9777777799********99999****************************7777777777777666633333333333444444444446665444 PP

                 .CHHTTT...........TTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTBETTCTCH.HCCCHHH CS
   PNP_UDP_1 135 .aaealg...........ikvhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArelgipfaairvvsdlaaggadaeatheeveefa 218
                  +                +++h+G++a+++++  + + ++r+ + +g+ + eME+a +       ++p+++ir++ d+ + +  +++        +
  EEA21505.1 200 qS----QliprearvtdgPTIHYGLIASGNQVMKDGKTRDRIAAPQGILCFEMEAAGLMD-----QLPYLVIRGICDYCDSHKNKHW-------QG 279
                 40....144444555556************************************987654.....79**********6666444443.......33 PP

>> TPR_3  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.0     0.073        46       9      24 ..     719     734 ..     713     735 .. 0.88
   2 ?   -1.2   0.0       3.5   2.2e+03       7      23 ..     759     775 ..     758     775 .. 0.88
   3 ?    4.0   0.0     0.083        53       1      23 [.     795     817 ..     795     817 .. 0.90
   4 ?    4.0   0.0     0.083        53       1      23 [.     837     859 ..     837     859 .. 0.90
   5 ?    4.8   0.0     0.044        28       5      23 ..     883     901 ..     881     901 .. 0.90
   6 ?   -2.6   0.0       9.6   6.1e+03       7      23 ..     927     943 ..     926     943 .. 0.87
   7 ?    4.0   0.0     0.079        50       7      23 ..    1011    1027 ..    1010    1029 .. 0.92

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.073
                 HHHHHTT-HHHHHHH. CS
       TPR_3   9 aefynkkkyqeArelf 24 
                 a +y+ ++y+eA+ +f
  EEA21505.1 719 ACLYSDGRYNEAEVFF 734
                 679***********94 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 3.5
                 HHHHHHHTT-HHHHHHH CS
       TPR_3   7 yAaefynkkkyqeArel 23 
                 +A ++ n+++ +eA+ l
  EEA21505.1 759 LASTYRNQGRWDEAEKL 775
                 789999********976 PP

  == domain 3  score: 4.0 bits;  conditional E-value: 0.083
                 HHHHHHHHHHHHHTT-HHHHHHH CS
       TPR_3   1 ldylysyAaefynkkkyqeArel 23 
                 l++ + +A ++ n+++ +eA+ l
  EEA21505.1 795 LNSMMNLASTYWNQGRWNEAEKL 817
                 578899**************976 PP

  == domain 4  score: 4.0 bits;  conditional E-value: 0.083
                 HHHHHHHHHHHHHTT-HHHHHHH CS
       TPR_3   1 ldylysyAaefynkkkyqeArel 23 
                 l++ + +A ++ n+++ +eA+ l
  EEA21505.1 837 LNSMMNLASTYWNQGRWNEAEKL 859
                 578899**************976 PP

  == domain 5  score: 4.8 bits;  conditional E-value: 0.044
                 HHHHHHHHHTT-HHHHHHH CS
       TPR_3   5 ysyAaefynkkkyqeArel 23 
                 + +A +++++++ +eA+ l
  EEA21505.1 883 MNLASTYQSQGRWNEAEKL 901
                 779*************976 PP

  == domain 6  score: -2.6 bits;  conditional E-value: 9.6
                 HHHHHHHTT-HHHHHHH CS
       TPR_3   7 yAaefynkkkyqeArel 23 
                 +A ++ n+++ +eA+ l
  EEA21505.1 927 LASTYRNQGRWNEAEKL 943
                 788999********976 PP

  == domain 7  score: 4.0 bits;  conditional E-value: 0.079
                  HHHHHHHTT-HHHHHHH CS
       TPR_3    7 yAaefynkkkyqeArel 23  
                  +A +++++++ +eA+ l
  EEA21505.1 1011 LASTYQSQGRWNEAEKL 1027
                  79************988 PP

>> TPR_4  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.0      0.01       6.6       3      21 ..     755     773 ..     753     775 .. 0.90
   2 ?    3.7   0.0       0.2   1.3e+02       5      21 ..     799     815 ..     796     817 .. 0.89
   3 ?    3.7   0.0       0.2   1.3e+02       5      21 ..     841     857 ..     838     859 .. 0.89
   4 ?   -0.4   0.0       4.1   2.7e+03       5      21 ..     883     899 ..     880     900 .. 0.88
   5 ?   -0.1   0.0       3.3   2.1e+03       6      21 ..     926     941 ..     925     942 .. 0.90
   6 ?   -0.3   0.0       3.8   2.4e+03       6      21 ..     968     983 ..     966     984 .. 0.89
   7 ?    0.4   0.0       2.4   1.5e+03       4      21 ..    1008    1025 ..    1006    1026 .. 0.89

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.01
       TPR_4   3 allaLArallalGdldeAr 21 
                   ++LA ++  +G++deA+
  EEA21505.1 755 SMANLASTYRNQGRWDEAE 773
                 6789**************7 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.2
       TPR_4   5 laLArallalGdldeAr 21 
                  +LA +++ +G++ eA+
  EEA21505.1 799 MNLASTYWNQGRWNEAE 815
                 69***********9997 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.2
       TPR_4   5 laLArallalGdldeAr 21 
                  +LA +++ +G++ eA+
  EEA21505.1 841 MNLASTYWNQGRWNEAE 857
                 69***********9997 PP

  == domain 4  score: -0.4 bits;  conditional E-value: 4.1
       TPR_4   5 laLArallalGdldeAr 21 
                  +LA +++ +G++ eA+
  EEA21505.1 883 MNLASTYQSQGRWNEAE 899
                 68999*******99996 PP

  == domain 5  score: -0.1 bits;  conditional E-value: 3.3
       TPR_4   6 aLArallalGdldeAr 21 
                 +LA ++  +G++ eA+
  EEA21505.1 926 NLASTYRNQGRWNEAE 941
                 8999********9996 PP

  == domain 6  score: -0.3 bits;  conditional E-value: 3.8
       TPR_4   6 aLArallalGdldeAr 21 
                 +LA ++  +G++ eA+
  EEA21505.1 968 NLASTYRNQGRWNEAE 983
                 8999*******99996 PP

  == domain 7  score: 0.4 bits;  conditional E-value: 2.4
       TPR_4    4 llaLArallalGdldeAr 21  
                   ++LA +++ +G++ eA+
  EEA21505.1 1008 MANLASTYQSQGRWNEAE 1025
                  579***********9996 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0       0.2   1.3e+02      31      49 ..     719     737 ..     712     775 .. 0.60
   2 !    7.4   0.0    0.0082       5.2       2      75 ..     766     856 ..     765     859 .. 0.54
   3 ?    4.7   0.0     0.054        35      19      48 ..     833     862 ..     819     901 .. 0.56
   4 ?    2.2   0.0      0.34   2.2e+02       4      45 ..     894     943 ..     891     953 .. 0.72
   5 ?    1.4   0.0       0.6   3.8e+02      23      44 ..    1005    1026 ..     975    1069 .. 0.62
   6 ?    0.3   0.0       1.3   8.6e+02      24      47 ..    1048    1071 ..    1018    1084 .. 0.72

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.2
                 HHHHHTT-HHHHHHHHHCT CS
      ANAPC3  31 lclylngqykrAyellrka 49 
                  cly++g+y++A  ++r++
  EEA21505.1 719 ACLYSDGRYNEAEVFFRDT 737
                 5888888888887666654 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0082
                 TT-HHHHHHHHHHHH.........HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCTSHHHC-H.........HHHHHHHHHHHHTT-HHHH CS
      ANAPC3   2 qnnyknAiflaerll........aaetespedayllAlclylngqykrAyellrkaklnsksl.........gcrylfAqcllkLkkyeeA 75 
                 q+++++A+ l   ++        a +++ +++ + lA ++ ++g++++A +l  +  ++s +          ++ + +A ++  +++++eA
  EEA21505.1 766 QGRWDEAEKLEVQVMeksmtvrgAEHPNTLNSMMNLASTYWNQGRWNEAEKLEVQVMEKSMTVrgaehpntlNSMMNLASTYWNQGRWNEA 856
                 5666666666666666555555556778888888888888888888888765333322222212222222225555555555555555555 PP

  == domain 3  score: 4.7 bits;  conditional E-value: 0.054
                 HH--HHHHHHHHHHHHHTT-HHHHHHHHHC CS
      ANAPC3  19 etespedayllAlclylngqykrAyellrk 48 
                 +++ +++ + lA ++ ++g++++A +l  +
  EEA21505.1 833 HPNTLNSMMNLASTYWNQGRWNEAEKLEVQ 862
                 566667777777777777777777665333 PP

  == domain 4  score: 2.2 bits;  conditional E-value: 0.34
                 -HHHHHHHHHHHH.........HHH--HHHHHHHHHHHHHTT-HHHHHHH CS
      ANAPC3   4 nyknAiflaerll........aaetespedayllAlclylngqykrAyel 45 
                 ++++A+ l   ++        a +++ + ++  lA ++ ++g++++A +l
  EEA21505.1 894 RWNEAEKLEVQVMeisttvlgAEHPDTLTSIANLASTYRNQGRWNEAEKL 943
                 5556666666666555544445667778888889***********99765 PP

  == domain 5  score: 1.4 bits;  conditional E-value: 0.6
                  HHHHHHHHHHHHHTT-HHHHHH CS
      ANAPC3   23 pedayllAlclylngqykrAye 44  
                  + +   lA ++ ++g++++A +
  EEA21505.1 1005 LTSMANLASTYQSQGRWNEAEK 1026
                  4444446777777777777755 PP

  == domain 6  score: 0.3 bits;  conditional E-value: 1.3
                  HHHHHHHHHHHHTT-HHHHHHHHH CS
      ANAPC3   24 edayllAlclylngqykrAyellr 47  
                   ++   A ++ ++g++++A +l  
  EEA21505.1 1048 ASIANMASTYRNQGRWNEAEKLEA 1071
                  444446888999999999887655 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0       6.5   4.2e+03      17      35 ..     662     680 ..     653     690 .. 0.82
   2 ?    5.1   0.0     0.075        48       7      23 ..     759     775 ..     756     775 .. 0.92
   3 ?    3.0   0.0      0.36   2.3e+02       7      23 ..     801     817 ..     797     817 .. 0.92
   4 ?    3.0   0.0      0.36   2.3e+02       7      23 ..     843     859 ..     839     859 .. 0.92
   5 ?    1.7   0.0      0.96   6.1e+02       7      23 ..     927     943 ..     924     966 .. 0.89
   6 ?    1.2   0.0       1.4   8.9e+02       7      23 ..     969     985 ..     968     996 .. 0.91
   7 ?    0.5   0.0       2.4   1.5e+03       7      23 ..    1053    1069 ..    1049    1070 .. 0.91

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 6.5
      TPR_14  17 pdeAiallrralalaPdda 35 
                 +  A+++++ + + +Pdd+
  EEA21505.1 662 HTSARRAADSLEEVFPDDD 680
                 5679999999999999985 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.075
      TPR_14   7 laeallalGdpdeAial 23 
                 la+ ++++G++deA++l
  EEA21505.1 759 LASTYRNQGRWDEAEKL 775
                 899***********986 PP

  == domain 3  score: 3.0 bits;  conditional E-value: 0.36
      TPR_14   7 laeallalGdpdeAial 23 
                 la+ ++++G++ eA++l
  EEA21505.1 801 LASTYWNQGRWNEAEKL 817
                 89************986 PP

  == domain 4  score: 3.0 bits;  conditional E-value: 0.36
      TPR_14   7 laeallalGdpdeAial 23 
                 la+ ++++G++ eA++l
  EEA21505.1 843 LASTYWNQGRWNEAEKL 859
                 89************986 PP

  == domain 5  score: 1.7 bits;  conditional E-value: 0.96
      TPR_14   7 laeallalGdpdeAial 23 
                 la+ ++++G++ eA++l
  EEA21505.1 927 LASTYRNQGRWNEAEKL 943
                 899***********997 PP

  == domain 6  score: 1.2 bits;  conditional E-value: 1.4
      TPR_14   7 laeallalGdpdeAial 23 
                 la+ ++++G++ eA++l
  EEA21505.1 969 LASTYRNQGRWNEAEKL 985
                 899***********997 PP

  == domain 7  score: 0.5 bits;  conditional E-value: 2.4
      TPR_14    7 laeallalGdpdeAial 23  
                  +a+ ++++G++ eA++l
  EEA21505.1 1053 MASTYRNQGRWNEAEKL 1069
                  7999**********986 PP

>> DUF4074  Domain of unknown function (DUF4074)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.0      0.74   4.8e+02      42      62 ..     755     775 ..     739     776 .. 0.81
   2 ?   -0.5   0.0       2.5   1.6e+03      44      62 ..     799     817 ..     787     818 .. 0.85
   3 ?   -0.5   0.0       2.5   1.6e+03      44      62 ..     841     859 ..     829     860 .. 0.85
   4 ?    3.5   0.0      0.14        90      44      62 ..     883     901 ..     870     902 .. 0.82
   5 ?    1.3   0.0      0.69   4.4e+02      42      62 ..     923     943 ..     913     944 .. 0.82
   6 ?   -0.4   0.0       2.3   1.5e+03      45      62 ..     968     985 ..     962     986 .. 0.90
   7 ?    4.4   0.1     0.074        47      42      62 ..    1007    1027 ..     993    1028 .. 0.82
   8 ?   -1.0   0.0       3.5   2.2e+03      44      62 ..    1051    1069 ..    1043    1070 .. 0.82

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.74
     DUF4074  42 tYtdLsahhtsqGriqeapkL 62 
                 + ++L++ +  qGr  ea kL
  EEA21505.1 755 SMANLASTYRNQGRWDEAEKL 775
                 56799999**********998 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 2.5
     DUF4074  44 tdLsahhtsqGriqeapkL 62 
                  +L++ +  qGr  ea kL
  EEA21505.1 799 MNLASTYWNQGRWNEAEKL 817
                 578899999*******998 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 2.5
     DUF4074  44 tdLsahhtsqGriqeapkL 62 
                  +L++ +  qGr  ea kL
  EEA21505.1 841 MNLASTYWNQGRWNEAEKL 859
                 578899999*******998 PP

  == domain 4  score: 3.5 bits;  conditional E-value: 0.14
     DUF4074  44 tdLsahhtsqGriqeapkL 62 
                  +L++ + sqGr  ea kL
  EEA21505.1 883 MNLASTYQSQGRWNEAEKL 901
                 5799999*********998 PP

  == domain 5  score: 1.3 bits;  conditional E-value: 0.69
     DUF4074  42 tYtdLsahhtsqGriqeapkL 62 
                 + ++L++ +  qGr  ea kL
  EEA21505.1 923 SIANLASTYRNQGRWNEAEKL 943
                 456899999**********98 PP

  == domain 6  score: -0.4 bits;  conditional E-value: 2.3
     DUF4074  45 dLsahhtsqGriqeapkL 62 
                 +L++ +  qGr  ea kL
  EEA21505.1 968 NLASTYRNQGRWNEAEKL 985
                 68889999********98 PP

  == domain 7  score: 4.4 bits;  conditional E-value: 0.074
     DUF4074   42 tYtdLsahhtsqGriqeapkL 62  
                  + ++L++ + sqGr  ea kL
  EEA21505.1 1007 SMANLASTYQSQGRWNEAEKL 1027
                  457899************998 PP

  == domain 8  score: -1.0 bits;  conditional E-value: 3.5
     DUF4074   44 tdLsahhtsqGriqeapkL 62  
                  +++++ +  qGr  ea kL
  EEA21505.1 1051 ANMASTYRNQGRWNEAEKL 1069
                  567788899*******998 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.0   3.2e-06     0.002       1      63 [.     321     376 ..     321     462 .. 0.70

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 3.2e-06
      AAA_16   1 rlvGReeeleqLlsalervrsgrpelvllsGesGvGKsslvrellralekdggiflrgkcdql 63 
                 r+vGR++++ +L+++++   s +p  + l+G  G+GK+ ++ el+ ++++        kc  +
  EEA21505.1 321 RFVGRQDQMTRLENLMS--MSYGPMKIALTGLGGMGKTQIALELAYRMRDG-----DDKCSVF 376
                 79**************9..567788899*************9999766655.....3444444 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0     3e-05     0.019       8     128 ..     345     462 ..     340     471 .. 0.77

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 3e-05
      AAA_22   8 lvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsst.sskdllrellralglelkaerlsseellealeqalrarav.ielliiDEaqhlr 104
                 +++tG  G+GKT  + +l+++       +  ++  vf  +++s  s ++ +  +++ l l+  +      ++  +++ +l++ ++ + lli D+a+ ++
  EEA21505.1 345 IALTGLGGMGKTQIALELAYRMR-----DGDDKCSVFWIPSVSQeSVEQAYMSIAQHLRLPDAN----PADVKMRVQSYLSHERAgRWLLICDNADDMD 434
                 789*****************983.....3345555666666666699999*********86665....99999999999999999999**********8 PP

      AAA_22 105 ...s...eealeeLrsllnlsrkgvqliLv 128
                    s    + l+ L+ +l   +++   iL+
  EEA21505.1 435 mwvSrdrTTPLTALSAFLP--QSDHGCILF 462
                 8884334555555554444..555555555 PP

>> DUF1897  Domain of unknown function (DUF1897)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.059        38      18      34 ..     763     779 ..     761     781 .. 0.93
   2 ?   -1.4   0.0       2.6   1.6e+03      18      34 ..     805     821 ..     805     823 .. 0.87
   3 ?   -1.4   0.0       2.6   1.6e+03      18      34 ..     847     863 ..     847     865 .. 0.87
   4 ?    2.7   0.1      0.14        87      18      34 ..     889     905 ..     888     907 .. 0.93
   5 ?   -0.2   0.0       1.1   7.1e+02      18      29 ..     931     942 ..     930     947 .. 0.88
   6 ?   -0.2   0.0       1.1   7.1e+02      18      29 ..     973     984 ..     972     989 .. 0.88
   7 ?    1.4   0.0      0.36   2.3e+02      18      34 ..    1015    1031 ..    1013    1033 .. 0.91
   8 ?    5.4   0.1      0.02        13      18      34 ..    1057    1073 ..    1054    1075 .. 0.94

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.059
     DUF1897  18 YrsiGmheeAeaieqqi 34 
                 Yr +G  +eAe  e q+
  EEA21505.1 763 YRNQGRWDEAEKLEVQV 779
                 *************9997 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 2.6
     DUF1897  18 YrsiGmheeAeaieqqi 34 
                 Y  +G   eAe  e q+
  EEA21505.1 805 YWNQGRWNEAEKLEVQV 821
                 6679********99997 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 2.6
     DUF1897  18 YrsiGmheeAeaieqqi 34 
                 Y  +G   eAe  e q+
  EEA21505.1 847 YWNQGRWNEAEKLEVQV 863
                 6679********99997 PP

  == domain 4  score: 2.7 bits;  conditional E-value: 0.14
     DUF1897  18 YrsiGmheeAeaieqqi 34 
                 Y s+G   eAe  e q+
  EEA21505.1 889 YQSQGRWNEAEKLEVQV 905
                 99**********99997 PP

  == domain 5  score: -0.2 bits;  conditional E-value: 1.1
     DUF1897  18 YrsiGmheeAea 29 
                 Yr +G   eAe 
  EEA21505.1 931 YRNQGRWNEAEK 942
                 **********95 PP

  == domain 6  score: -0.2 bits;  conditional E-value: 1.1
     DUF1897  18 YrsiGmheeAea 29 
                 Yr +G   eAe 
  EEA21505.1 973 YRNQGRWNEAEK 984
                 **********95 PP

  == domain 7  score: 1.4 bits;  conditional E-value: 0.36
     DUF1897   18 YrsiGmheeAeaieqqi 34  
                  Y s+G   eAe   +q+
  EEA21505.1 1015 YQSQGRWNEAEKLDMQV 1031
                  99*********998886 PP

  == domain 8  score: 5.4 bits;  conditional E-value: 0.02
     DUF1897   18 YrsiGmheeAeaieqqi 34  
                  Yr +G   eAe  e+q+
  EEA21505.1 1057 YRNQGRWNEAEKLEAQV 1073
                  ****************7 PP

>> Urocanase_N  Urocanase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0      0.11        71      85     117 ..     747     779 ..     737     789 .. 0.85
   2 ?   -2.2   0.0       4.9   3.1e+03      86     117 ..     790     821 ..     782     830 .. 0.80
   3 ?   -2.1   0.0       4.4   2.8e+03      86     117 ..     832     863 ..     810     874 .. 0.80
   4 ?   -1.3   0.0       2.5   1.6e+03      86     116 ..     874     904 ..     852     912 .. 0.85
   5 ?    2.3   0.0       0.2   1.3e+02      86     123 ..     916     953 ..     910     955 .. 0.87
   6 ?    3.3   0.0     0.098        62      86     117 ..     958     989 ..     955     996 .. 0.88
   7 ?   -1.0   0.0         2   1.3e+03      86     115 ..    1042    1071 ..    1033    1079 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.11
                  TTS-SEEEEES-B-GGG-SHHHHHHHHHTT--- CS
  Urocanase_N  85 eeaPrvliansnlvpkyateeefeeleakgltm 117
                  ++ P  l++ +nl ++y ++ +++e+e++++ +
   EEA21505.1 747 KNHPSTLVSMANLASTYRNQGRWDEAEKLEVQV 779
                  6789***********************998864 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 4.9
                  TS-SEEEEES-B-GGG-SHHHHHHHHHTT--- CS
  Urocanase_N  86 eaPrvliansnlvpkyateeefeeleakgltm 117
                  e P  l +  nl ++y ++ +++e+e++++ +
   EEA21505.1 790 EHPNTLNSMMNLASTYWNQGRWNEAEKLEVQV 821
                  568888888999999*********99998754 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 4.4
                  TS-SEEEEES-B-GGG-SHHHHHHHHHTT--- CS
  Urocanase_N  86 eaPrvliansnlvpkyateeefeeleakgltm 117
                  e P  l +  nl ++y ++ +++e+e++++ +
   EEA21505.1 832 EHPNTLNSMMNLASTYWNQGRWNEAEKLEVQV 863
                  56888888889999999999999999988754 PP

  == domain 4  score: -1.3 bits;  conditional E-value: 2.5
                  TS-SEEEEES-B-GGG-SHHHHHHHHHTT-- CS
  Urocanase_N  86 eaPrvliansnlvpkyateeefeeleakglt 116
                  e P  l +  nl ++y+++ +++e+e++++ 
   EEA21505.1 874 EHPDTLTSMMNLASTYQSQGRWNEAEKLEVQ 904
                  5688899999999**********99998875 PP

  == domain 5  score: 2.3 bits;  conditional E-value: 0.2
                  TS-SEEEEES-B-GGG-SHHHHHHHHHTT---B-TTTT CS
  Urocanase_N  86 eaPrvliansnlvpkyateeefeeleakgltmyGqmtA 123
                  e P  l + +nl ++y ++ +++e+e++g+ +    tA
   EEA21505.1 916 EHPDTLTSIANLASTYRNQGRWNEAEKLGVQVIETSTA 953
                  578899999********************988766665 PP

  == domain 6  score: 3.3 bits;  conditional E-value: 0.098
                  TS-SEEEEES-B-GGG-SHHHHHHHHHTT--- CS
  Urocanase_N  86 eaPrvliansnlvpkyateeefeeleakgltm 117
                  e P  li  +nl ++y ++ +++e+e++g+ +
   EEA21505.1 958 EHPDTLIRMGNLASTYRNQGRWNEAEKLGVQV 989
                  579999**********************9975 PP

  == domain 7  score: -1.0 bits;  conditional E-value: 2
                   TS-SEEEEES-B-GGG-SHHHHHHHHHTT- CS
  Urocanase_N   86 eaPrvliansnlvpkyateeefeeleakgl 115 
                   e P  l + +n+ ++y ++ +++e+e+++ 
   EEA21505.1 1042 EHPDTLASIANMASTYRNQGRWNEAEKLEA 1071
                   57888999999***********99998764 PP

>> Imm49  Immunity protein 49
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.3   0.00033      0.21      45     128 ..     745     835 ..     661     874 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00033
       Imm49  45 r...gagtwldafflallcrdneslrelaefptellrqs....gtrydeydyayidalqallddardpdaaeellaaleaalpreaaiaaa 128
                 +    ++t  ++  la + r++ +++e+ +++++++++s    g+++++  +++++   +++++ r++ a +  ++ +e++ ++ +a+  +
  EEA21505.1 745 NgknHPSTLVSMANLASTYRNQGRWDEAEKLEVQVMEKSmtvrGAEHPNTLNSMMNLASTYWNQGRWNEAEKLEVQVMEKSMTVRGAEHPN 835
                 2455778888888999999************************************************************988777765554 PP

>> TPR_6  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0       4.6     3e+03       5      24 ..     716     735 ..     712     739 .. 0.82
   2 ?    3.8   0.0      0.16     1e+02       3      20 ..     756     773 ..     754     775 .. 0.86
   3 ?    1.8   0.0      0.71   4.6e+02       2      20 ..     797     815 ..     796     817 .. 0.89
   4 ?    1.8   0.0      0.71   4.6e+02       2      20 ..     839     857 ..     838     859 .. 0.89
   5 ?    2.2   0.0      0.55   3.5e+02       2      20 ..     881     899 ..     880     901 .. 0.89
   6 ?    0.5   0.0       1.9   1.2e+03       5      20 ..     926     941 ..     923     943 .. 0.87
   7 ?    0.1   0.0       2.5   1.6e+03       5      20 ..     968     983 ..     968     985 .. 0.86
   8 ?    0.4   0.0       2.1   1.3e+03       3      20 ..    1008    1025 ..    1006    1027 .. 0.85
   9 ?    0.6   0.0       1.8   1.1e+03       5      20 ..    1052    1067 ..    1049    1069 .. 0.87

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 4.6
                 HHHHHHHHHHHHHHHHHHHH CS
       TPR_6   5 klalsyrklgdtdkAleale 24 
                 +++ ++++ g++ +A   ++
  EEA21505.1 716 RIGACLYSDGRYNEAEVFFR 735
                 8999****77****988776 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.16
                 HHHHHHHHHHHHHHHHHH CS
       TPR_6   3 lyklalsyrklgdtdkAl 20 
                 + +la  yr++g++d+A 
  EEA21505.1 756 MANLASTYRNQGRWDEAE 773
                 6789************96 PP

  == domain 3  score: 1.8 bits;  conditional E-value: 0.71
                 HHHHHHHHHHHHHHHHHHH CS
       TPR_6   2 AlyklalsyrklgdtdkAl 20 
                 ++++la  y ++g++ +A 
  EEA21505.1 797 SMMNLASTYWNQGRWNEAE 815
                 6899************995 PP

  == domain 4  score: 1.8 bits;  conditional E-value: 0.71
                 HHHHHHHHHHHHHHHHHHH CS
       TPR_6   2 AlyklalsyrklgdtdkAl 20 
                 ++++la  y ++g++ +A 
  EEA21505.1 839 SMMNLASTYWNQGRWNEAE 857
                 6899************995 PP

  == domain 5  score: 2.2 bits;  conditional E-value: 0.55
                 HHHHHHHHHHHHHHHHHHH CS
       TPR_6   2 AlyklalsyrklgdtdkAl 20 
                 ++++la  y+++g++ +A 
  EEA21505.1 881 SMMNLASTYQSQGRWNEAE 899
                 6899************995 PP

  == domain 6  score: 0.5 bits;  conditional E-value: 1.9
                 HHHHHHHHHHHHHHHH CS
       TPR_6   5 klalsyrklgdtdkAl 20 
                 +la  yr++g++ +A 
  EEA21505.1 926 NLASTYRNQGRWNEAE 941
                 68999********995 PP

  == domain 7  score: 0.1 bits;  conditional E-value: 2.5
                 HHHHHHHHHHHHHHHH CS
       TPR_6   5 klalsyrklgdtdkAl 20 
                 +la  yr++g++ +A 
  EEA21505.1 968 NLASTYRNQGRWNEAE 983
                 58999********995 PP

  == domain 8  score: 0.4 bits;  conditional E-value: 2.1
                  HHHHHHHHHHHHHHHHHH CS
       TPR_6    3 lyklalsyrklgdtdkAl 20  
                  + +la  y+++g++ +A 
  EEA21505.1 1008 MANLASTYQSQGRWNEAE 1025
                  6689***********995 PP

  == domain 9  score: 0.6 bits;  conditional E-value: 1.8
                  HHHHHHHHHHHHHHHH CS
       TPR_6    5 klalsyrklgdtdkAl 20  
                  ++a  yr++g++ +A 
  EEA21505.1 1052 NMASTYRNQGRWNEAE 1067
                  6999*********995 PP

>> DUF3574  Protein of unknown function (DUF3574)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       6.8   4.4e+03      42      84 ..     764     806 ..     761     813 .. 0.83
   2 ?   -2.1   0.0       5.2   3.4e+03      43      84 ..     807     848 ..     799     871 .. 0.80
   3 ?    1.5   0.0       0.4   2.6e+02      43      86 ..     849     892 ..     844     894 .. 0.91
   4 ?    2.3   0.0      0.23   1.5e+02      39      86 ..     887     934 ..     885     938 .. 0.90
   5 ?    5.6   0.0     0.021        13      39      86 ..    1013    1060 ..    1007    1114 .. 0.95

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 6.8
     DUF3574  42 dakGqwrdetgalirekskvlillhpdteakearieeireaYk 84 
                   +G+w ++++  ++   k +++   +++++ +++ +++++Y 
  EEA21505.1 764 RNQGRWDEAEKLEVQVMEKSMTVRGAEHPNTLNSMMNLASTYW 806
                 67899*9999999999999999999999998888888888885 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 5.2
     DUF3574  43 akGqwrdetgalirekskvlillhpdteakearieeireaYk 84 
                  +G+w+++++  ++   k +++   +++++ +++ +++++Y 
  EEA21505.1 807 NQGRWNEAEKLEVQVMEKSMTVRGAEHPNTLNSMMNLASTYW 848
                 479999988888888888888888888888888887777775 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.4
     DUF3574  43 akGqwrdetgalirekskvlillhpdteakearieeireaYker 86 
                  +G+w+++++  ++   k ++ll  +++++  ++ +++++Y+++
  EEA21505.1 849 NQGRWNEAEKLEVQVMEKSMTLLGAEHPDTLTSMMNLASTYQSQ 892
                 58***********************************9999875 PP

  == domain 4  score: 2.3 bits;  conditional E-value: 0.23
     DUF3574  39 tvldakGqwrdetgalirekskvlillhpdteakearieeireaYker 86 
                 ++++++G+w+++++  ++      ++l  +++++  +i++++++Y+++
  EEA21505.1 887 STYQSQGRWNEAEKLEVQVMEISTTVLGAEHPDTLTSIANLASTYRNQ 934
                 56899******999999999999999999****************976 PP

  == domain 5  score: 5.6 bits;  conditional E-value: 0.021
     DUF3574   39 tvldakGqwrdetgalirekskvlillhpdteakearieeireaYker 86  
                  ++++++G+w+++++  ++     +++l  +++++ a+i++++++Y+++
  EEA21505.1 1013 STYQSQGRWNEAEKLDMQVMEISITVLGAEHPDTLASIANMASTYRNQ 1060
                  57899****************************************986 PP

>> DUF4919  Domain of unknown function (DUF4919)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0       2.9   1.8e+03      85     115 ..     789     819 ..     747     831 .. 0.61
   2 ?    3.5   0.1     0.091        59      81     124 ..     869     912 ..     831     915 .. 0.78
   3 ?    3.7   0.0      0.08        51      75     123 ..     988    1037 ..     965    1041 .. 0.84
   4 ?   -1.6   0.0       3.4   2.2e+03      76     117 ..    1073    1115 ..    1043    1120 .. 0.66

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 2.9
     DUF4919  85 kknPfdlkqlnllayaykalgkkeeakiysk 115
                 +++P  l+ +++la  y ++g+ +ea++++ 
  EEA21505.1 789 AEHPNTLNSMMNLASTYWNQGRWNEAEKLEV 819
                 4566677777777777777777776666655 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.091
     DUF4919  81 eealkknPfdlkqlnllayaykalgkkeeakiyskrlnkllkai 124
                 + + +++P  l+ +++la  y+++g+ +ea++++ ++ ++ +++
  EEA21505.1 869 TLLGAEHPDTLTSMMNLASTYQSQGRWNEAEKLEVQVMEISTTV 912
                 3444678999**************************99999887 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.08
     DUF4919   75 eiislaeeal.kknPfdlkqlnllayaykalgkkeeakiyskrlnkllka 123 
                  ++i++++ +l +++P  l+ + +la  y+++g+ +ea+++  ++ ++  +
  EEA21505.1  988 QVIETSTTVLgAEHPTTLTSMANLASTYQSQGRWNEAEKLDMQVMEISIT 1037
                  67777888774579*************************99999988765 PP

  == domain 4  score: -1.6 bits;  conditional E-value: 3.4
     DUF4919   76 iislaeeal.kknPfdlkqlnllayaykalgkkeeakiyskrl 117 
                  +++ + ++l +++P  l+ +++la+  k  gk++ a  + ++ 
  EEA21505.1 1073 VMEKSMSVLgAEHPSTLTSMTILAFTWKDIGKQQDAILLMSQC 1115
                  3444444442567888999999999999988888777666665 PP

>> DUF3157  Protein of unknown function (DUF3157)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       9.4     6e+03      86     148 ..     508     570 ..     478     575 .. 0.69
   2 ?    3.6   0.1     0.067        43     132     183 ..     774     825 ..     771     833 .. 0.94
   3 ?    3.5   0.1     0.072        46     132     183 ..     816     867 ..     814     874 .. 0.94
   4 ?    3.7   0.1     0.064        41     132     183 ..     900     951 ..     875     954 .. 0.89
   5 ?    2.1   0.1       0.2   1.3e+02     133     183 ..    1027    1077 ..    1010    1080 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 9.4
     DUF3157  86 lakpellkslaksGvkvslskakyedgrLgLtfeltsqSsesvivvelevslyddsGellkte 148
                 ++ + ll++l+   + ++ ++a  + + + L+  ++   +++  v+el  + ++d+G+  +t+
  EEA21505.1 508 IKITALLRQLTFLPLAITQAAAYINANGIELSDYIELLQEQEHDVIELLSEDFEDEGRYAETQ 570
                 455566666666666666666666667777777777777777777788777788888777776 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.067
     DUF3157 132 elevslyddsGellktekvtvWqaifRmaetYLRkgqsrqsktieiegveks 183
                 +lev+++++s ++   e+ +  +++  +a tY  +g+ ++++ +e++++eks
  EEA21505.1 774 KLEVQVMEKSMTVRGAEHPNTLNSMMNLASTYWNQGRWNEAEKLEVQVMEKS 825
                 5899999999999999*********************************997 PP

  == domain 3  score: 3.5 bits;  conditional E-value: 0.072
     DUF3157 132 elevslyddsGellktekvtvWqaifRmaetYLRkgqsrqsktieiegveks 183
                 +lev+++++s ++   e+ +  +++  +a tY  +g+ ++++ +e++++eks
  EEA21505.1 816 KLEVQVMEKSMTVRGAEHPNTLNSMMNLASTYWNQGRWNEAEKLEVQVMEKS 867
                 5899999999999999*********************************997 PP

  == domain 4  score: 3.7 bits;  conditional E-value: 0.064
     DUF3157 132 elevslyddsGellktekvtvWqaifRmaetYLRkgqsrqsktieiegveks 183
                 +lev++++ s ++l  e+ +   +i  +a tY  +g+ ++++ + ++++e s
  EEA21505.1 900 KLEVQVMEISTTVLGAEHPDTLTSIANLASTYRNQGRWNEAEKLGVQVIETS 951
                 699*********************************************9975 PP

  == domain 5  score: 2.1 bits;  conditional E-value: 0.2
     DUF3157  133 levslyddsGellktekvtvWqaifRmaetYLRkgqsrqsktieiegveks 183 
                  l++++++ s ++l  e+ +   +i  ma tY  +g+ ++++ +e +++eks
  EEA21505.1 1027 LDMQVMEISITVLGAEHPDTLASIANMASTYRNQGRWNEAEKLEAQVMEKS 1077
                  6777888888888888889999***********************999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1212 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       525  (0.0292822); expected 358.6 (0.02)
Passed bias filter:                      405  (0.0225891); expected 358.6 (0.02)
Passed Vit filter:                        64  (0.00356964); expected 17.9 (0.001)
Passed Fwd filter:                        28  (0.00156172); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              28  [number of targets reported over threshold]
# CPU time: 0.94u 0.31s 00:00:01.25 Elapsed: 00:00:00.54
# Mc/sec: 6735.36
//
Query:       EEA21506.1  [L=570]
Description: nonsense-mediated mRNA decay protein Upf3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.1e-42  145.1   0.0    2.1e-42  145.1   0.0    3.8  3  Smg4_UPF3   Smg-4/UPF3 family
    3.2e-09   36.5   0.5      4e-08   32.9   0.1    2.7  3  RRM_1       RNA recognition motif. (a.k.a. RRM, RBD, or RNP d


Domain annotation for each model (and alignments):
>> Smg4_UPF3  Smg-4/UPF3 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.1   0.0   2.3e-46   2.1e-42       3     174 .]      33     199 ..      31     199 .. 0.92
   2 ?  -13.9  17.1         2   1.8e+04     134     134 ..     252     252 ..     197     301 .. 0.55
   3 ?   -1.8   0.8      0.31   2.8e+03     153     167 ..     391     425 ..     363     436 .. 0.52

  Alignments for each domain:
  == domain 1  score: 145.1 bits;  conditional E-value: 2.3e-46
   Smg4_UPF3   3 ktKvviRrLPPnLteeefleavsd..kplpetvdykyFvpGklskdslkeskysrayinfkdpedlvqfakkfdghvFvDskgnes......paivefA 93 
                 + K++iRrLPP Lt  ef + ++d  k +++++d+++F pGk+skd+ k+s+++ray++++++e + ++++k+++  F D+++++       p++vefA
  EEA21506.1  33 RLKLIIRRLPPGLTRAEFETGLGDdwKIGRGKIDWFQFKPGKISKDPAKPSRPARAYVHVLSEEIISSLSEKVRATSFHDARNTSNdpvllgPPSVEFA 131
                 68*********************999999*****************************************************88879************ PP

   Smg4_UPF3  94 pyqkvpkkkkkkkdakqgtIekDpeylaFleslekeeeekeseseeeklaeeaeekekekeakkekktttpLleylkekka 174
                 p+ +vp ++ ++kd +qgtI++Dpe++aFlesl ++ +++   + +e+++           +++e+ t tpL++++kekka
  EEA21506.1 132 PFARVPGSR-SRKDGRQGTIDQDPEFVAFLESLTNPITKPIPVE-GETEK-----------KEEEEITITPLVQFIKEKKA 199
                 ******988.************************9999854444.33333...........335899************96 PP

  == domain 2  score: -13.9 bits;  conditional E-value: 2
   Smg4_UPF3 134 e 134
                 +
  EEA21506.1 252 T 252
                 1 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 0.31
   Smg4_UPF3 153 k....................eakkekktttpLle 167
                                      +ak++k+++t+ + 
  EEA21506.1 391 GpgtstttdsavpattprapkAAKQQKPKQTAVIS 425
                 14444444455555555555556666666666554 PP

>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0      0.45     4e+03       1      15 [.      36      50 ..      36      52 .. 0.84
   2 ?   -0.3   0.0      0.11   9.5e+02      44      62 ..     191     209 ..     188     213 .. 0.86
   3 !   32.9   0.1   4.5e-12     4e-08       8      58 ..     439     484 ..     436     493 .. 0.93

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.45
                EEEESETTTSSHHHH CS
       RRM_1  1 lfVgnLppdvteeeL 15
                l+++ Lpp +t+ e 
  EEA21506.1 36 LIIRRLPPGLTRAEF 50
                6899*******9876 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.11
                 EEESSHHHHHHHHHHHTTE CS
       RRM_1  44 VeFeskedAekAlealngk 62 
                 V+F ++  A kA+++   k
  EEA21506.1 191 VQFIKEKKASKAKDSASSK 209
                 99***********987665 PP

  == domain 3  score: 32.9 bits;  conditional E-value: 4.5e-12
                 TTSSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHH CS
       RRM_1   8 pdvteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlea 58 
                 + vtee L + Fs fG+++++++ ++     kgf++V+F+  e+ +kA++a
  EEA21506.1 439 QGVTEELLDAAFSAFGKVTKVEIDKK-----KGFGYVDFAEAESLQKAIAA 484
                 679***************99999997.....******************85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (570 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1983  (0.110603); expected 358.6 (0.02)
Passed bias filter:                      535  (0.0298399); expected 358.6 (0.02)
Passed Vit filter:                       117  (0.00652574); expected 17.9 (0.001)
Passed Fwd filter:                        55  (0.00306766); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 1.49u 0.43s 00:00:01.92 Elapsed: 00:00:00.65
# Mc/sec: 2652.18
//
Query:       EEA21507.1  [L=391]
Description: TOR signaling pathway phosphatase SitA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.3e-35  121.8   0.0    4.7e-34  118.7   0.0    2.0  1  Metallophos      Calcineurin-like phosphoesterase
  ------ inclusion threshold ------
      0.099   12.3   0.0       0.15   11.7   0.0    1.2  1  Glyco_hydro_65N  Glycosyl hydrolase family 65, N-terminal dom


Domain annotation for each model (and alignments):
>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.7   0.0   5.2e-38   4.7e-34       2     201 ..      61     321 ..      60     324 .. 0.86

  Alignments for each domain:
  == domain 1  score: 118.7 bits;  conditional E-value: 5.2e-38
                  EEEEEESBTBTTCCTHHHHHHHHHHHH...................................................................HHHT CS
  Metallophos   2 rilvigDlHlalgggqlddllkllddl...................................................................lree 32 
                  +++++gD+H     gq++dll+l++ +                                                                    +++
   EEA21507.1  61 PVTICGDIH-----GQFYDLLELFRVAggmpnetnveppantppvitsddieppstitdpklrkkiknadslldgddsasgrgrsgsgsskevtGPPP 153
                  799******.....**********55555555556666666666666666677777777777777787777788777777777777666666654447 PP

                  TESEEEEESTSSSSSHHHHHHHHH.HHHHHHHTSEEEEEC-TTS........CHHHHHHHHHHHHHHHHHHHEHHHCEEETSEEEEEETTEEEEEEEE CS
  Metallophos  33 kpdlvllaGDlvdrgdlekellel.laalvkypipvylllGNHe........gfeeellnkygylgifsepwrsdaevfnnlplaslgsgslkvlllh 121
                  ++ ++l  GD+vdrg ++ e+l l l+ + kyp+++ l++GNHe        gf+ee+++kyg+    + +w+ +++vf+++ l ++++g  kvl++h
   EEA21507.1 154 GNFVFL--GDYVDRGYFSLETLTLlLCLKAKYPDRITLVRGNHEsrqitqvyGFYEECFQKYGN----ASVWKACCQVFDFMTLGAIIDG--KVLCVH 243
                  889999..*******555555555599999999******************************9....99********************..****** PP

                  SE.CEEETHHHHHHHHHHHSCHHHHCC...HHHHHHHHHHTTCSEEEEEESSESSCSSSCSCCHHHHHHHHHHTTESEEEEESS CS
  Metallophos 122 Gg.spellvsldklgslnleleapepg...dewlkdlekrekadwvivlgHsplyrgsgylfgdealedllkkygvdlvisGHt 201
                  Gg spe+  +ld+++ + + +e+p++g   d+ ++d     + d   v ++   +rg+g+lfg++++e+++  +++ l+ ++H+
   EEA21507.1 244 GGlSPEI-RTLDQVRVVARAQEIPHEGafcDLVWSD-----PEDAADVETWAVSPRGAGWLFGNKVAEEFCHVNDLSLIARAHQ 321
                  **98888.****************************.....99999999999999****************************7 PP

>> Glyco_hydro_65N  Glycosyl hydrolase family 65, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   1.7e-05      0.15      26      84 ..     190     243 ..     188     258 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 1.7e-05
                      E----TTTT--.-EEETT-EE-T........TSSS-EE----EEEEEEEEETTEE--GG CS
  Glyco_hydro_65N  26 tRgafeeeysdpgtyiaGvYdreiseeanGypeeneelvnlpdwlglrlrvdgeeldld 84 
                      +Rg++e     + t + G+Y++    +++G + +++ ++++ d+++l   +dg+ l + 
       EEA21507.1 190 VRGNHES--R-QITQVYGFYEEC--FQKYGNASVWKACCQVFDFMTLGAIIDGKVLCVH 243
                      6999999..4.59*******888..78**************************888775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (391 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       539  (0.030063); expected 358.6 (0.02)
Passed bias filter:                      481  (0.026828); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.69u 0.36s 00:00:01.04 Elapsed: 00:00:00.58
# Mc/sec: 2030.58
//
Query:       EEA21508.1  [L=398]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (398 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       966  (0.0538792); expected 358.6 (0.02)
Passed bias filter:                      632  (0.0352502); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.69u 0.33s 00:00:01.02 Elapsed: 00:00:00.54
# Mc/sec: 2217.26
//
Query:       EEA21509.1  [L=497]
Description: aldehyde dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.3e-183  609.9   0.1   2.6e-183  609.8   0.1    1.0  1  Aldedh    Aldehyde dehydrogenase family
  ------ inclusion threshold ------
        0.2   11.1   0.0       0.39   10.1   0.0    1.4  1  GAIN      GPCR-Autoproteolysis INducing (GAIN) domain


Domain annotation for each model (and alignments):
>> Aldedh  Aldehyde dehydrogenase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  609.8   0.1  2.9e-187  2.6e-183       3     462 .]      29     487 ..      27     487 .. 0.98

  Alignments for each domain:
  == domain 1  score: 609.8 bits;  conditional E-value: 2.9e-187
                 T-SS.SEEEEEETTTCEEEEEEE-B-HHHHHHHHHHHHHHHH.HHTTS-HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH---HHHHHHHHHHHHHHHHH CS
      Aldedh   3 eses.etievinPatgeviakvpaataedvdaavaaAkeafk.awaklpaeeRaeiLrkaadlleerkeelaeletletGkplaearaeveeaidvlry 99 
                 ++ + +t+e+inP++++vi++v +at++dvd av+aA++a +  w++++++eR+++L k+adl+ee+ + la +e+l++Gk +  a+++++    +lry
  EEA21509.1  29 KGVEgKTFETINPHDEKVITSVYEATEKDVDIAVKAARDALSgPWKHITPTERGRLLTKLADLFEENMDVLAGIESLDNGKATVFAKGDIQAGSYCLRY 127
                 5556478**********************************988******************************************************* PP

                 HHHHHHHHSEEEEEECTTEEEEEEEEE-SEEEEEE-SSSCCHHHHHHHHHHHHTT-EEEEEE-TTSHHHHHHHHHHHHHTTS-TTSEEE--SSTCCHHH CS
      Aldedh 100 yaelaeklegevlpssegklalvrrePlGvvgaItPWNfPlllaawklapalaaGNtvvlKPaeetplsalllaelfeeaglPkgvlnvvtgsgsevge 198
                 y ++ +k+ g+++ +++++l+++ +eP+Gv+g+I+PWNfP+l++awk+ pa+a+GNtvvlK ae+tplsal  a l+++ag+P+gv+nv++g g+ +g+
  EEA21509.1 128 YGGWSDKIVGQTIDTDSTSLNYTLHEPVGVCGQIIPWNFPILMWAWKIGPAIATGNTVVLKTAEQTPLSALFAATLIQKAGFPPGVINVLSGFGRVAGA 226
                 ***************99********************************************************************************** PP

                 HHHH-TTESEEEEES-HHHHHHHHHH.HHCTTSEEEEEE---EEEEE-TTSHHHHHHHHHHHHHHGGGGTSTTSEEEEEEEHHHHHHHHHHHHHHHHT- CS
      Aldedh 199 alvehpevdkvsftGstevgrkiaka.aaknlkrvtlElGGknplivledaDldkaveaivkgafgnaGQvCiaasrllvqesiydefveklveaakkl 296
                 a+ +h ++dkv+ftGst vgr+i++a a++nlk+vtlElGGk+p+iv++da+l++a+++i +g+++n GQ C+a+sr+lv+e iyd+f+e+++++a+k 
  EEA21509.1 227 AISSHMDIDKVAFTGSTLVGRQILQAaAKSNLKKVTLELGGKSPNIVFPDANLENAISWINFGIYFNHGQCCCAGSRVLVHEAIYDKFLEAFKARAEKN 325
                 **************************5559********************************************************************* PP

                 -BS-TTSTT-SB---SSHHHHHHHHHHHHHHHHTTSEEEE-TTE.SB-SSSTTEE--EEEES-TTTSHHHHS---SSEEEEEEESSHHHHHHHHHSSSE CS
      Aldedh 297 kvgdpldedtdvGPliseaqlekvekyveeakeegaklllGgereeaglekgyfvePtvlanvtpdmriaqeEiFGPVlsvikfkdeeeaieiaNdtey 395
                 kvg+p+de t  GP++s+ q++++++y++e+k++gak+++Gg   e+  +kgy+++Pt++a+v+++m+i+qeEiFGPV +v kfkdeeea+++aNdt y
  EEA21509.1 326 KVGNPFDEGTYQGPQVSQIQFDRIMGYIDEGKKAGAKVVVGG---ERLGDKGYYIKPTIFADVNNEMKIVQEEIFGPVCTVQKFKDEEEALKLANDTTY 421
                 ******************************************...7789************************************************** PP

                 ESEEEEE-SBHHHHHHHHHHS-SSEEEESSSST--TTTSEB--CGGGEES-BSHHHHHHHTEEEEEE CS
      Aldedh 396 GLaagvftkdleraervaerleaGnvyiNdsttgaaealpfgGvkqSglGreggkegleeytevktv 462
                 GLaagv+t+dl++a rv+++l+aG+v++N+++t + ++ pfgG+k+SglGre g+++le+yt++k+v
  EEA21509.1 422 GLAAGVHTNDLNTAIRVSNALKAGTVWVNQYNTPHYQT-PFGGYKESGLGRELGSYALENYTQIKAV 487
                 *************************************9.**************************87 PP

>> GAIN  GPCR-Autoproteolysis INducing (GAIN) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   4.3e-05      0.39      67      95 ..      72     100 ..      48     108 .. 0.94

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 4.3e-05
        GAIN  67 sWedlqqseqgtaatkLlrtleeyallla 95 
                  W+++  +e+g+ +tkL +++ee++++la
  EEA21509.1  72 PWKHITPTERGRLLTKLADLFEENMDVLA 100
                 5**************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (497 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       481  (0.026828); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.26s 00:00:00.85 Elapsed: 00:00:00.48
# Mc/sec: 3129.27
//
Query:       EEA21510.1  [L=486]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (486 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       772  (0.0430587); expected 358.6 (0.02)
Passed bias filter:                      554  (0.0308997); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.44
# Mc/sec: 3291.92
//
Query:       EEA21511.1  [L=478]
Description: 1,3-beta-glucanosyltransferase Gel2 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   3.2e-120  401.1   0.7   4.4e-120  400.7   0.7    1.1  1  Glyco_hydro_72  Glucanosyltransferase


Domain annotation for each model (and alignments):
>> Glyco_hydro_72  Glucanosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  400.7   0.7  2.4e-124  4.4e-120       4     314 ..      17     332 ..      15     333 .. 0.97

  Alignments for each domain:
  == domain 1  score: 400.7 bits;  conditional E-value: 2.4e-124
                     XSSTTS--EEEETTEEEETTT-BBE-EEEEE--BE------SSB-GGG-HHHHHHHHHHHHHHT-SEEEES---TTS--HHHHHHHHHTT-EEEE CS
  Glyco_hydro_72   4 aaeeaveaieikgnkffdsksgeqfyikGvdyqpggseevsslvdpladaeaCkrdikllkelgvntvrvyavdnskdhdeCmkalsdagiyvil 98 
                     ++++av+++ +kg+ f+d+ +g++f i Gvdyqpggs+  + ++dpl+d++aC rd+++l+ lgvn +rvy++ +s++hdeC +++++agiy+il
      EEA21511.1  17 STAAAVNPVVVKGKDFVDTVTGDRFQIVGVDYQPGGSSGFKGTADPLSDKDACLRDAAILQYLGVNSIRVYNLAPSANHDECASIFNAAGIYMIL 111
                     567899********************************99******************************************************* PP

                     ES-BT..TBS--TTS-..---HHHHHHHHHHHHHHTT-TTEEEEEEEESSS-STT-GGGHHHHHHHHHHHHHHHHHSSS----EEEEE---TTTH CS
  Glyco_hydro_72  99 dlnep..kesinradpassynedllervfkvidafkeyknvlgffaGnevvndksntaasayvkavvrdvkeyikkkkerkiPvGysaaddaelr 191
                     d+n+p  + s+nr  p++syn +++ +vf vi+afk+y+n+ gff+Gnev+n+ s +  + y++av+rd+++yi+k+++r iPvGysaad++ l 
      EEA21511.1 112 DVNSPldNGSLNRGAPWESYNPVYMAQVFGVIEAFKNYPNTAGFFSGNEVINEDSVALVPNYIRAVQRDMHDYISKNSKRPIPVGYSAADVRPLL 206
                     *****9889************************************************************************************** PP

                     HHHHHHTTBTT-.....--S-EEEEE----SS--HHHHSHHHHHHHHTT-SS-EEEEEE---SSSS---THHHHHTSHHHHTTEEEEEES-SB-- CS
  Glyco_hydro_72 192 velaeylaCgded...dkadffglnmyeWCgkssfktsGydertkefenysiPlflseyGCnkvtprkftevealyseemtsvfsGGlvyeysee 283
                     v+ a y++C+  +   +++dffgln+y+WCg  +++tsGy+  t++f+n+++P+f+se GCn+v+pr+f+e++a+y+ +m++  sG lvyey++e
      EEA21511.1 207 VDSAYYFTCNLANstnSRSDFFGLNSYSWCGDATYTTSGYNVLTEDFTNITVPVFFSETGCNNVRPRVFSEIQAIYGPDMSQALSGALVYEYTQE 301
                     *********96654446****************************************************************************** PP

                     SSS--SEEE-TTS-EEE-THHHHHHHHHHH- CS
  Glyco_hydro_72 284 annyGlvkiddddvkkllkdfenlkseykki 314
                     an+yGlv+++++++++ll dfenl+s+y+k+
      EEA21511.1 302 ANDYGLVNLNSNGTVSLLVDFENLRSQYSKL 332
                     ****************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (478 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       663  (0.0369792); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.39
# Mc/sec: 3635.31
//
Query:       EEA21512.1  [L=785]
Description: meiotic recombination protein Mre11 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.5e-56  190.6   1.3    6.5e-56  189.3   1.3    1.8  1  Mre11_DNA_bind  Mre11 DNA-binding presumed domain
    2.2e-14   54.5   1.2    4.2e-14   53.5   1.2    1.5  1  Metallophos     Calcineurin-like phosphoesterase
      0.003   17.8   0.0      0.032   14.4   0.0    2.5  1  Metallophos_2   Calcineurin-like phosphoesterase superfamily 
  ------ inclusion threshold ------
       0.13   11.0   0.0        0.2   10.4   0.0    1.2  1  Baculo_gp64     Baculovirus gp64 envelope glycoprotein family
       0.66   10.8   6.6         15    6.4   0.2    2.7  2  CHIP_TPR_N      CHIP N-terminal tetratricopeptide repeat doma


Domain annotation for each model (and alignments):
>> Mre11_DNA_bind  Mre11 DNA-binding presumed domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  189.3   1.3   1.8e-59   6.5e-56       1     169 []     296     474 ..     296     474 .. 0.95

  Alignments for each domain:
  == domain 1  score: 189.3 bits;  conditional E-value: 1.8e-59
                     EEEEEEE-SSS--EEEEEEECCC-TTT-...CCTS-CCCHHHHHHHHHHHHHHHHHHHH.......SSSTTS------EEEEEEE-T....TT-- CS
  Mre11_DNA_bind   1 FklepipLktvRpfvlkeisLsdvaelk...kkeknkekvtkflrekVeelieeaeeew.......eeeaeeeepplPLiRLrVdys....ggfe 81 
                     Fk epipLktvRpfv+kei+Ls+++  k   +ke+n++++t++l+  Ve+lie+a++ew         ++ee+e+plPL+RLrV++s    g+f+
      EEA21512.1 296 FKNEPIPLKTVRPFVMKEIVLSEDKTAKklaRKENNRTEITRLLMTYVEDLIEQAKAEWletheddIGDDEEPEIPLPLVRLRVETStpdgGSFD 390
                     899********************99988999********************************99977899*******************99*** PP

                     ---HHHHHHCCCTTBS-SSSSEEEE-S-XXXXXXXXXXXXXXX......XXXXXXXXXCHHHHHHHHHHS.XXTTSXHHHHHHHHHHH CS
  Mre11_DNA_bind  82 venpqrfgqrFvgkVANpndvlqfyrkkkarkkkkkekaaakeeeellaeaekldklkvedlVkeyleaqekLkllpekglneAveeF 169
                     +enpqrf++rFvgkVAN+ndv+qf+rkkk+++++kk++ +a++     ++ ++ld++kve+lV+e+l+aq +L++lp++ +++Av++F
      EEA21512.1 391 CENPQRFSNRFVGKVANVNDVVQFHRKKKTTTSRKKDDLDAEA---AVSHLSTLDTVKVEQLVRELLTAQ-SLTILPQNLFGDAVTQF 474
                     *****************************99998887766666...7778899*****************.***************99 PP

>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.5   1.2   1.2e-17   4.2e-14       1     204 []      16     251 ..      16     251 .. 0.69

  Alignments for each domain:
  == domain 1  score: 53.5 bits;  conditional E-value: 1.2e-17
                  EEEEEEESBTB.......TTCCTHHHHHHHHHHHHHHHTTESEEEEESTSSSSS..............................HHHHHHHHHHHHHH CS
  Metallophos   1 lrilvigDlHl.......algggqlddllkllddllreekpdlvllaGDlvdrg..............................dlekellellaalv 61 
                  +rilv +D H+        +g+ ++ ++ +++  l++e ++d+vllaGDl++++                              d             
   EEA21512.1  16 IRILVSTDNHVgynerdpIRGDDSWKTFHEIM-CLAKERDVDMVLLAGDLFHENkpsrksmyqvmrslranclgdkpcelellsD------------- 99 
                  59************888888888888888888.557777***************6666666666666666666655555555553............. PP

                  HH....................TSEEEEEC-TTSCHHHHHHHHHHHHHHHHHHHEHHHCEEETSEEEEEETTEEEEEEEESECEEE.THHHHHHHHHH CS
  Metallophos  62 ky....................pipvylllGNHegfeeellnkygylgifsepwrsdaevfnnlplaslgsgslkvlllhGgspel.lvsldklgsln 138
                                         ipv+ ++GNH+    + +      +++  +     ++++  p ++ +    k +ll  g   l l+ l++++ + 
   EEA21512.1 100 -AsenfqgafnhvnyedldinvAIPVFSIHGNHD----DPSGEGHLAALDILQVSGLLNYYGRTPESDNIQV--KPVLLQKGRTKLaLYGLSNVRDER 190
                  .0333444444455568888899***********....4444444444443333333444477777776666..666666664555778889999999 PP

                  HSCHHHHCCHHHHHHHHHHTTCSEEEEEESSESSCSSSCSCCHHHHHHHHHHTTESEEEEESSSSE CS
  Metallophos 139 leleapepgdewlkdlekrekadwvivlgHsplyrgsgylfgdealedllkkygvdlvisGHtHvy 204
                  l+++  +++ ++++      k dw  +++ + ++    y+      e++l ++ +dlvi+GH+H++
   EEA21512.1 191 LFRTFRDGKVKFFQP--SVQKEDWFNLICVHQNH--HAYTETGYLPENFLPEF-LDLVIWGHEHEC 251
                  998888877777777..66667777777766666..46666666666777777.9*********85 PP

>> Metallophos_2  Calcineurin-like phosphoesterase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.0     9e-06     0.032       3     145 ..      18     270 ..      16     292 .. 0.56

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 9e-06
  Metallophos_2   3 laiiSDlH............snldaleavlealkevgvdaiihaGDl.eeeep.......................................evle 46 
                    +++ +D H            ++ +   +++  +ke +vd++++aGDl  e +p                                       +v  
     EEA21512.1  18 ILVSTDNHvgynerdpirgdDSWKTFHEIMCLAKERDVDMVLLAGDLfHENKPsrksmyqvmrslranclgdkpcelellsdasenfqgafnHV-- 111
                    67777777777777777777677777788888999999********655555555555555555555566666666655555555444443311.. PP

  Metallophos_2  47 ellela..........pvlaVrGNnD.............................eev.veedvlreaaelgtdl.......peeaelelagekvl 95 
                         +          pv  ++GN+D                             +++ v+  +l++  +    l        e+ + ++++ kv 
     EEA21512.1 112 -----NyedldinvaiPVFSIHGNHDdpsgeghlaaldilqvsgllnyygrtpesDNIqVKPVLLQKGRTKLA-LyglsnvrDERLFRTFRDGKVK 201
                    .....12222234567**********88888888888887777777777777765333233333333322222.2355554323333333333433 PP

  Metallophos_2  96 liHgdpl...........gvkdalaellke.....aeegsd..vvvcGHtHvpeveke....ggvlvvnPGs 145
                    ++  + +           +   + ++ +++     +  +++  +v+ GH H+  ++ +    ++  v  PGs
     EEA21512.1 202 FFQPSVQkedwfnlicvhQ---NHHAYTETgylpeNFLPEFldLVIWGHEHECLIDPKlnpeTNFHVMQPGS 270
                    3333322444455542221...22222222111223444446699999999985555543336777777887 PP

>> Baculo_gp64  Baculovirus gp64 envelope glycoprotein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   5.6e-05       0.2     183     256 ..     282     358 ..     257     388 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 5.6e-05
                  EETTEEEEEE--S-EEEEEE...EEEEEEEST--TT-----EEEEEETTEEEEE-SSEEEETTEEEEE-TT------ CS
  Baculo_gp64 183 tekdvsyllkdkseitreev...kiacllikdywvgerktkkafcqdktnfdevtreqflidydiydlskdelleav 256
                  + k+vs+l     e+++e +    +  ++ k+  ++e kt k +++ ++n  e+tr  + +  d+ + +k e+le+ 
   EEA21512.1 282 VTKQVSILSITGREFKNEPIplkTVRPFVMKEIVLSEDKTAKKLARKENNRTEITRLLMTYVEDLIEQAKAEWLETH 358
                  5677888888888888887733224579**********************************************975 PP

>> CHIP_TPR_N  CHIP N-terminal tetratricopeptide repeat domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.2    0.0041        15       5      49 ..     324     368 ..     322     384 .. 0.77
   2 ?    5.9   1.7    0.0063        23      28      79 ..     487     538 ..     477     541 .. 0.83

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0041
                 HHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCTTCCHGTTTSXCH CS
  CHIP_TPR_N   5 rfrkeEekRikqEieLqsyLnkLideDkerkleeleeeeekeede 49 
                 +  ++E++R +    L +y+++Li++ k++ le+ e +  ++e+ 
  EEA21512.1 324 KLARKENNRTEITRLLMTYVEDLIEQAKAEWLETHEDDIGDDEEP 368
                 557899999999999***************999765554444444 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0063
                 HHHHHHCCCTTCCHGTTTSXCHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHC CS
  CHIP_TPR_N  28 ideDkerkleeleeeeekeedekleeeeeeieeeaderlaeLnelFaqvder 79 
                 ++e ++ ++++l + e++ + e+ +e+ +++++  +++  +++++Fa+   +
  EEA21512.1 487 VNESLDSQIKHLLTLERDADFEDEDETHQSLRNAMEKYRGQMEDMFAKGSVK 538
                 67778889999977888888888889*********************96555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (785 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1211  (0.0675442); expected 358.6 (0.02)
Passed bias filter:                      591  (0.0329634); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.80u 0.34s 00:00:01.14 Elapsed: 00:00:00.49
# Mc/sec: 4771.60
//
Query:       EEA21513.1  [L=1151]
Description: F-box and WD domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.7e-10   40.6   0.0    3.5e-10   39.6   0.0    1.5  1  F-box-like  F-box-like
    6.9e-09   35.4   0.0    2.7e-08   33.5   0.0    1.9  2  F-box       F-box domain
  ------ inclusion threshold ------
      0.015   15.2   0.0      0.046   13.6   0.0    1.8  1  F-box_4     F-box


Domain annotation for each model (and alignments):
>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.6   0.0   5.8e-14   3.5e-10       3      45 ..     128     169 ..     126     172 .. 0.92

  Alignments for each domain:
  == domain 1  score: 39.6 bits;  conditional E-value: 5.8e-14
  F-box-like   3 rLPdEiLlqIFsyLppsdLlrlalVCrrWrrvaldtplLWrrl 45 
                  LP+E+L +I+s+L+p  L+++alV+rr+++++ +tp  Wr+ 
  EEA21513.1 128 GLPNEVLTHILSHLSPAALTAIALVSRRFHTLV-TTPHAWRTA 169
                 6*******************************9.567****96 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.5   0.0   4.5e-12   2.7e-08       3      45 ..     126     168 ..     125     171 .. 0.93
   2 ?   -1.9   0.0      0.57   3.4e+03      26      33 ..     572     579 ..     571     579 .. 0.91

  Alignments for each domain:
  == domain 1  score: 33.5 bits;  conditional E-value: 4.5e-12
                 HHHS-HHHHHHHHHTS-HHHHHHHCTT-HHHHHHHTTHHHHHH CS
       F-box   3 lsrLPsevlrhILerLplsdllalrrVSkgwrilidsdrlwck 45 
                 l  LP+evl hIL++L++  l a+++VS++++ l+  +  w++
  EEA21513.1 126 LAGLPNEVLTHILSHLSPAALTAIALVSRRFHTLVTTPHAWRT 168
                 678*********************************9999986 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.57
                 HCTT-HHH CS
       F-box  26 lrrVSkgw 33 
                 +r+V+ gw
  EEA21513.1 572 FRKVCEGW 579
                 8******9 PP

>> F-box_4  F-box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.0   7.8e-06     0.046       3      38 ..     124     159 ..     122     165 .. 0.91

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 7.8e-06
     F-box_4   3 dsLssLPlevlqhiaslLDsfsLsqLslvskllrev 38 
                 +sL  LP evl+hi+s L   +L+ ++lvs+++  +
  EEA21513.1 124 QSLAGLPNEVLTHILSHLSPAALTAIALVSRRFHTL 159
                 6899***************************98765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1151 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       532  (0.0296726); expected 358.6 (0.02)
Passed bias filter:                      329  (0.0183502); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.72u 0.28s 00:00:01.00 Elapsed: 00:00:00.45
# Mc/sec: 7741.32
//
Query:       EEA21514.1  [L=548]
Description: amino acid permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.2e-61  208.0  49.8    2.6e-61  207.7  49.8    1.0  1  AA_permease_2  Amino acid permease
      5e-15   55.1  43.2    8.9e-15   54.2  43.1    1.4  1  AA_permease    Amino acid permease
  ------ inclusion threshold ------
        1.4    8.9   6.1          6    6.8   2.4    2.8  2  DUF2678        Protein of unknown function (DUF2678)


Domain annotation for each model (and alignments):
>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  207.7  49.8   4.4e-65   2.6e-61       1     425 []      61     504 ..      61     504 .. 0.86

  Alignments for each domain:
  == domain 1  score: 207.7 bits;  conditional E-value: 4.4e-65
  AA_permease_2   1 lsllsafalvigsvigsgifvkn...laasggpalilwvwiavligslavllvyaEl.ssalprsgGiyvytkaafgkkva....flsawfnwfay 88 
                    +++ls+f +++++   ++ ++++    +++gg a+++w w+++++g++++++  aEl s+  p+sgG+y  ++++ ++++     +l++w+n++++
     EEA21514.1  61 FGYLSTFSFAFSISGLFATIATTfsyPLYAGGSASAIWCWLISGAGCMCLAASVAELvSA-YPTSGGLYFTVSRLAPPRWVpslsWLTGWINLLGQ 155
                    6788888888888844444444444467899999***********************877.**************9999988999*********** PP

  AA_permease_2  89 vpvlasilsvaasyllnalgp....dlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfsslstetd 180
                    v+++as+ +  a++ll a++     +++++t lt+++++a+++l+ ++n++ + ++ k++   +i+++l +l++  i+ l+    + ++      +
     EEA21514.1 156 VAGIASSEYGSAQMLLAAVSMsrdfEWVPTTGLTIGVMAALTVLCGVLNSLPTGWMEKMTRSYVIFHLL-VLVTCCIALLVK-TEDKHD-----AK 244
                    ******************975678899999**************************************5.655555444444.455554.....33 PP

  AA_permease_2 181 tffpn.....gwp..g..vllgllivlwsfdGfesaanvseevkk..kdvpkaifigllivlvlyllvniaflgvvpddeianlsnlgs.vaalff 264
                    ++f+n     gw+  g  +l+g+l v w+++ +++ a+++ee++    ++p aif++++ v vl++++n+++ ++++d +    s+  + va++f+
     EEA21514.1 245 YVFTNveqnsGWTptGfsFLFGFLSVSWTMTDYDATAHIAEEIRDpeVKAPWAIFLAMGAVYVLGFFFNLVLCFCMGDVSSILASPMAQpVAQIFY 340
                    4444444445777441335999********************6654269*****************************887666776662689999 PP

  AA_permease_2 265 eavggkvvaiivvilialsllgaintavigssrvlealardgvlP..rffakvn.kfgspiraiiltaivslillllfllassaaynfllsvsslg 357
                    + +g k +  +  +++++ l ++ +ta+ + +r+++a++rd+ lP  + ++kvn  +g+p++a+++++  + i + l+ l+s++a+  ++++++++
     EEA21514.1 341 NSLG-KSGGLVYTACAFILLQFICFTATQALARTVFAFSRDRLLPfsNIWRKVNsTTGTPLYAVWFSVFWC-IAINLIGLGSYTAILGVFNITAIA 434
                    9999.7777777789999999999**********************************************9.7778999999************** PP

  AA_permease_2 358 liisylll.iigalilrkkrp..hlkrpgkilvaiigalfllfllvalffppkgpatqssliytiiltval 425
                    l +sy ++ ++ +l++r+ +   h +++   +v++ ++++++f+ v++ffp+++p+t+++++y+i++++++
     EEA21514.1 435 LDWSYVIPvVCKLLWNRFEPGpwHMGKFS-TIVNLWAVIWTVFASVIFFFPTARPVTGETMNYAIVFMAFI 504
                    ********667788999995522446675.56**********************************99986 PP

>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.2  43.1   1.5e-18   8.9e-15      17     464 ..      82     514 ..      68     524 .. 0.79

  Alignments for each domain:
  == domain 1  score: 54.2 bits;  conditional E-value: 1.5e-18
  AA_permease  17 vglgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrf....lgpelGfviGlnylfswitvlal.eltaasiliqfwelvtd 109
                  +  ++ l ++G ++a+ ++l++g+  ++ + s++e+++++p sgg y+ +sr     + p+l++ +G++ l+ +++++a  e++ a++l+  +++ +d
   EEA21514.1  82 TTFSYPLYAGGSASAIWCWLISGAGCMCLAASVAELVSAYPTSGGLYFTVSRLapprWVPSLSWLTGWINLLGQVAGIASsEYGSAQMLLAAVSMSRD 179
                  55678999****************************************9999822225568899999999999**99995499999999999977555 PP

  AA_permease 110 ...lpkawvtgavflvvlliinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkga..gfrflgdngsifknnlppgfakeeegafknfi 202
                     +p++  t+ v+ ++ +++ +++    g +e ++ +++i  ++ ++ + i ll++ + +++a   f+++ +n++    + p g          +f+
   EEA21514.1 180 fewVPTTGLTIGVMAALTVLCGVLNSLPTGWMEKMTRSYVIFHLLVLVTCCIALLVKTEDKHDAkyVFTNVEQNSG----WTPTG---------FSFL 264
                  2225555555778888888888888888899999999999999999999998888888888887779999999999....88888.........68** PP

  AA_permease 203 svfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasaaspfvifikesgvsvlaplinaviltaa 300
                  ++f  v+ ++t + ++a ia+E++dPe + P ai  ++  + ++  ++ l++ +++++ + ++l++ +    p+  ++ +s  +  + + +a+ ++ +
   EEA21514.1 265 FGFLSVSWTMTDYDATAHIAEEIRDPEVKAPWAIFLAMGAVYVLGFFFNLVLCFCMGDVS-SILASPMA--QPVAQIFYNSLGKSGGLVYTACAFILL 359
                  *********************************987775444444444444444444333.44444443..46777777777788899999999**** PP

  AA_permease 301 lssansslysasRvlyslakdglaP...kvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliilsylrfRkalk 395
                   ++   ++ +  R+++++++d+l+P    + k+ s  g Pl a+ +s ++  ++     + l+  +++  + +i+a++    +++  ++ l + + ++
   EEA21514.1 360 QFICFTATQALARTVFAFSRDRLLPfsnIWRKVNSTTGTPLYAVWFSVFWCIAIN---LIGLGSYTAILGVFNITAIALDWSYVIPVVCKLLW-NRFE 453
                  ***************************7788888899********9987755555...44455446888888999998888888888888855.4445 PP

  AA_permease 396 yqgrsieelgfkaallplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfliilv 464
                     +++        + + + ++ +a++++++  + ++ +++ + +++++++a ++ a++ +  ++  +v
   EEA21514.1 454 PGPWHM--------GKFSTIVNLWAVIWTVFASVIFFFPTARPVTGETMNYAIVFMAFILLCAMVYWYV 514
                  555544........77778889999999999999888899989999****9988777776655555444 PP

>> DUF2678  Protein of unknown function (DUF2678)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.1     0.029   1.7e+02      32      77 ..     188     235 ..     175     244 .. 0.77
   2 ?    6.8   2.4     0.001         6      41      86 ..     470     517 ..     459     520 .. 0.77

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.029
     DUF2678  32 lvvggltsllvlvtvvssfv..fpslppkplniffavcillisssviv 77 
                 l++g +++l vl  v+ s+   + ++  ++  if  ++++ ++++ +v
  EEA21514.1 188 LTIGVMAALTVLCGVLNSLPtgWMEKMTRSYVIFHLLVLVTCCIALLV 235
                 789999999999999999851144556677778877777777776665 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.001
     DUF2678  41 lvlvtvvssfv..fpslppkplniffavcillisssvivlifwyrqgd 86 
                  v+ tv +s++  fp++ p + + +    ++++ +  + +++wy +g+
  EEA21514.1 470 AVIWTVFASVIffFPTARPVTGETMNYAIVFMAFILLCAMVYWYVRGK 517
                 477888888652279999988888777778999999999*****9885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (548 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       768  (0.0428356); expected 358.6 (0.02)
Passed bias filter:                      303  (0.0169); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.47
# Mc/sec: 3486.57
//
Query:       EEA21515.1  [L=698]
Description: protease inhibitor (Tfs1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-07   31.5   1.2    4.6e-06   27.0   0.1    2.7  2  PBP       Phosphatidylethanolamine-binding protein


Domain annotation for each model (and alignments):
>> PBP  Phosphatidylethanolamine-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.0   0.1   2.5e-10   4.6e-06       2     103 ..      38     122 ..      28     156 .. 0.76
   2 ?   -3.8   0.1      0.83   1.5e+04      43      62 ..     176     195 ..     170     220 .. 0.61

  Alignments for each domain:
  == domain 1  score: 27.0 bits;  conditional E-value: 2.5e-10
                 --GGGCSBGGS..-EEEEE.S--TTSSEEEEEEEETTS..CCTCT..TEEEEEEEEEETTSSEE-TTCEE-B-TTSSCCCCS---B--STTS..EEEEE CS
         PBP   2 lpkkyegents..Pplsws.dvpegtksyalvviDpDa..pkvse..tflHwvvtnipasvtslpegavqgknslgeesesgYlgpcPpkgdgkHrYvf 93 
                 +pk+    + +  P+l++  ++ + +++y ++ iD+Da  p++++  ++lHwv+ n++                             P  g  +HrY+f
  EEA21515.1  38 IPKA----DAQnpPELRLPqSLASSSDTYLMIAIDIDApfPSWRGlgPILHWVQPNLK---------------------------LDPATGRSPHRYCF 105
                 4555....444468888875555689************9989999855*********9...........................478888888***** PP

                 EEE....EESSSG...- CS
         PBP  94 lly....aldvea...l 103
                 +ly    +ldv++   +
  EEA21515.1 106 FLYkqpeGLDVAKyvsK 122
                 ***99998888874331 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 0.83
                 EEEEEEEEEETTSSEE-TTC CS
         PBP  43 flHwvvtnipasvtslpega 62 
                 ++H+  +n+  s ++ ++++
  EEA21515.1 176 YIHYHHINLDESINNSAKDN 195
                 78888888885555544433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (698 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       291  (0.0162307); expected 358.6 (0.02)
Passed bias filter:                      259  (0.0144459); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.30s 00:00:00.95 Elapsed: 00:00:00.50
# Mc/sec: 4184.92
//
Query:       EEA21516.1  [L=599]
Description: amino acid transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-34  118.4  24.6    4.8e-34  117.8  24.6    1.2  1  Aa_trans  Transmembrane amino acid transporter protein


Domain annotation for each model (and alignments):
>> Aa_trans  Transmembrane amino acid transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.8  24.6   2.7e-38   4.8e-34      19     376 ..     136     508 ..     120     517 .. 0.86

  Alignments for each domain:
  == domain 1  score: 117.8 bits;  conditional E-value: 2.7e-38
    Aa_trans  19 aGvLaLPyAfkqlGlivGlillllvallslytlllLvkcsktla.sgkrnksYgdlgyrllGpkgkliidlailvqlfGvgvsyliligdllpaifesf 116
                  G ++LP+Af ++G+ +G++l++++a l +y+ +lL ++   l+  +  ++++gdlg rl+Gp+++++i++++ +ql+  +   +i  g+ l+++ ++ 
  EEA21516.1 136 LGPFGLPFAFGTMGWGPGIALYTVFAGLAIYSGYLLWDMFLGLDsFHYPIRHFGDLGFRLFGPWMRHLINVLQSIQLILNVGLIVISNGEALSQVAKF- 233
                 5678*************************************99998899******************************999999999*********8. PP

    Aa_trans 117 fdtlllsnvyfilisaliiipLslipnlskLsylSllalvsslyy........................ivilvlvvaelvklelkgvseetv...... 185
                     +l+  +  li a++ ++  +i+ l+k+++++ la+ + l++                        i     ++  l +++  + s+ +v      
  EEA21516.1 234 ----KLCYIICCLIWAIVGFLVGQIRTLQKFGWIANLAVWLNLLCmfitmggashygpnydsvgsasgaI-----INGGLSVTQNPDLSWPPVqtsggl 323
                 ....5666666789999999999***************99998888999*************99555544.....444555555555555555555558 PP

    Aa_trans 186 kkasklkglflaigiivFAftghavlleiqnelkdpskfkkmtkvlllsiilatvlyilvGlvGYltFGnevkgnillnlpkssilivivnlllvlhli 284
                   + +++g+++ +  +vFA++g++v++e+++e+k p++f      + ++ +++++ y++ Gl+ Y   G  +     l  + +  +++++n++  l ++
  EEA21516.1 324 PHSDNFAGTISGAMQAVFAYGGAMVFPEFMAEMKRPKDFL---TGMWAAQLFIYFWYMFYGLFMYGYQGQYTVNPSYLGISSYG-IQTAGNVFAFLSAV 418
                 7888899********************************9...79999999********************************9.************** PP

    Aa_trans 285 lsfplqlhplrqvvenllikkeavagasekeapkskll.rlvirlllvvityliAlsvpslakvlslvGatsstplsfilPalfhlkliktek 376
                 ++  l+    ++v+ n+++ +   ++  +  ++k ++  ++++  ++  i+ +iA+ +p+++ + s+v a+++  +++++P+lf +    +++
  EEA21516.1 419 IAAALYGNIGVKVLYNSIFVE---IFRFPPLTTKGGKIsWVILIPIYWSIAFIIAAAIPNFSGLTSVVAAFCILHFTYTFPPLFAIVYWAKKF 508
                 ******************986...5555555555555505555555666667789*****************************987666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (599 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       703  (0.0392102); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 4124.36
//
Query:       EEA21517.1  [L=308]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.1e-37  126.4   0.1    3.2e-36  124.6   0.1    1.7  1  adh_short      short chain dehydrogenase
    4.5e-36  124.6   0.3    1.7e-28   99.8   0.1    2.9  2  adh_short_C2   Enoyl-(Acyl carrier protein) reductase
    8.3e-12   45.4   0.1    9.3e-11   42.0   0.1    2.0  1  KR             KR domain
     0.0004   19.9   0.6     0.0038   16.7   0.6    2.3  1  Epimerase      NAD dependent epimerase/dehydratase family
      0.006   16.0   0.1      0.069   12.5   0.0    2.0  2  GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
     0.0075   15.3   0.2      0.011   14.8   0.2    1.1  1  OMP_b-brl_3    Outer membrane protein beta-barrel family


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  124.6   0.1   1.1e-39   3.2e-36       4     190 ..      13     221 ..      10     225 .. 0.85

  Alignments for each domain:
  == domain 1  score: 124.6 bits;  conditional E-value: 1.1e-39
                 EEESTTSHHHHHHHHHHHHTT-EEEE...EESCHHHHHHHHHHHHHT.TSEEEEEE-TTTSH.HHHHHHHHHHHHHH.............SSESEEEE- CS
   adh_short   4 lvtGassGIGraiakelakeGakvvv...vdrseekleevakelkee.gakalaiqvDvtdr.eevealvekavkkl.............gkldvLvnN 84 
                 +vtG+s+GIG a++++la++G+++++    ++s e  e++ +el  + + ++  +q+D+td   ++ ++v+ a++ +              ++d+L+nN
  EEA21517.1  13 IVTGGSRGIGEAVVRRLAAKGCNLLIvytSNSSTELTEKISSELSTThNIHISSVQADLTDPvGATPKIVAGAKAFYksytarsrsskeeLQVDILINN 111
                 8**********************9984212334566788888998888999*********76256677887777666555666677776678******* PP

                 --S.....S--SSGGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEE CS
   adh_short  85 AGi.....tgsgpfselseeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnava 178
                 AG+      ++++   ++ +e++rv++vN+ +++llt+a++p +   +sGrIvnvsSv +  +++g+++Y+ +Kaa++++tr++++el ++  +vnav+
  EEA21517.1 112 AGVgsnqfLNDATKGPIDVTEYNRVYNVNVLAPLLLTQALAPFLPTDRSGRIVNVSSVSSSIGYEGQSVYAGTKAALEAMTRCWSRELYDK-ATVNAVN 209
                 ***76666555666667889999******************************************************************97.9****** PP

                 ESSBSSHHHHHH CS
   adh_short 179 PGlvdTdmakel 190
                 PG+   dm +++
  EEA21517.1 210 PGPAWGDMYAQA 221
                 **9888887665 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.8   0.1   5.7e-32   1.7e-28       3     201 ..      18     241 ..      12     252 .. 0.79
   2 !   20.2   0.0   1.2e-07   0.00036     184     233 ..     254     303 ..     244     304 .. 0.85

  Alignments for each domain:
  == domain 1  score: 99.8 bits;  conditional E-value: 5.7e-32
                   TTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSE..E....EE--TTSHHH.HHHHHHHHHHHH.............SSEEEEEE---- CS
  adh_short_C2   3 asgIGraiAkalaeeGaevvltdlneeakkrveelaeelgae..v....lecDVtdeeq.vealveevvekf.............gklDilvnnagi 79 
                    +gIG+a++++la++G+++++++ ++++ + +e++ +el+++  +    +++D td+     ++v+ +++ +              ++Dil+nnag+
    EEA21517.1  18 SRGIGEAVVRRLAAKGCNLLIVYTSNSSTELTEKISSELSTThnIhissVQADLTDPVGaTPKIVAGAKAFYksytarsrsskeeLQVDILINNAGV 114
                   49*************************************9665646699******985313333333332221111111222222579********* PP

                   -EG..CSS-GGG..H-HHHHHHHHHHHTHHHHHHHHHHHHHCTSC..CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEE CS
  adh_short_C2  80 apk..lkgpfle..tsreefdraldvnlyslfllakaalplmkeg..gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavs 170
                     +  l +++++  ++  e++r+ +vn+ + +ll++a++p +     g+ivn+ssv+++++ +++++y+ +Kaalea+tr++ +el + + +vNav 
    EEA21517.1 115 GSNqfL-NDATKgpIDVTEYNRVYNVNVLAPLLLTQALAPFLPTDrsGRIVNVSSVSSSIGYEGQSVYAGTKAALEAMTRCWSRELYD-KATVNAVN 209
                   **9963.4444424799***********************6655548****************************************9.99****** PP

                   E--BHCTG.GGGSTTHHHHHHHHHHHSTTSS- CS
  adh_short_C2 171 pgpikTla.asgikgfdelleelearaplgrl 201
                   pgp   ++ a++ ++f ++ +   + apl   
    EEA21517.1 210 PGPAWGDMyAQAGEKFWKINQPYVDAAPLAAY 241
                   ********455555599999999999998764 PP

  == domain 2  score: 20.2 bits;  conditional E-value: 1.2e-07
                   THHHHHHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEESTTG CS
  adh_short_C2 184 gfdelleelearaplgrlgtpeevaeaalfLasdeasyitGqtlvvDgGl 233
                   +++++ + +++    +r g ++e+a ++++L+ +e+ ++tG+++ ++gG+
    EEA21517.1 254 DAERFDKTVREGMGGRRPGFTSEIAGTIVMLCTEESGWTTGSVVCANGGM 303
                   4566777777777788999******************************8 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.0   0.1   3.1e-14   9.3e-11       4     169 ..      13     201 ..      11     211 .. 0.77

  Alignments for each domain:
  == domain 1  score: 42.0 bits;  conditional E-value: 3.1e-14
                 EEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHT.T-EEEE----TT-HHHHHHH..............HHHHHHHSS---EEEE CS
          KR   4 litGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaeleal.gaevevvaaDvsdkdaveal..............leeikaeeppikGvih 87 
                 ++tGG  g+G +++r la+kg + l++ + + +++e  ++  +el+ + +++++ v+aD++d+   +                 ++ ++ee ++   i+
  EEA21517.1  13 IVTGGSRGIGEAVVRRLAAKGCNLLIVYTSN-SSTELTEKISSELSTThNIHISSVQADLTDPVGATPKivagakafyksytaRSRSSKEELQVDILIN 110
                 79*******************8777776666.4677777788999886589********9997543221111222222222223334445579999*** PP

                 ---------TTT--H.....HHHHHHHTTTTHHHHHHHHHTTT....S--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHHHHHT CS
          KR  88 aAgvlrdklleemta.....edleqvlapKvkGawnLhelled....esldffvlfSSiagllgsagqanYaaaNaflDalaeyrrsqglp 169
                  Agv  ++ l++ t+      ++++v++  v +   L ++l++    ++   +v +SS+++ +g  gq+ Ya + a l+a+ + ++++   
  EEA21517.1 111 NAGVGSNQFLNDATKgpidvTEYNRVYNVNVLAPLLLTQALAPflptDRSGRIVNVSSVSSSIGYEGQSVYAGTKAALEAMTRCWSRELYD 201
                 **********99886333226889**************999988666777789****************************9998876554 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.6   1.3e-06    0.0038       2      55 ..      13      77 ..      13     212 .. 0.69

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 1.3e-06
                EEETTTSHHHHHHHHHHHHCTSE.EEEEES-STTTTCHHCHHC.........EEEE--TT-HH.H CS
   Epimerase  2 lVtGatGfiGsalvkallekgye.vigldrlssasntarledl.........elveldltdrs.a 55
                +VtG++  iG a+v++l++kg + +i+ +++ss++ t+++            + v++dltd++ a
  EEA21517.1 13 IVTGGSRGIGEAVVRRLAAKGCNlLIVYTSNSSTELTEKISSElstthnihiSSVQADLTDPVgA 77
                69*******************99777777776666666665559999999996666666666533 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.5   0.0   2.3e-05     0.069       2      64 ..      14      74 ..      13      85 .. 0.77
   2 ?    1.2   0.0     0.064   1.9e+02     147     170 ..     175     198 ..     164     209 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 2.3e-05
                   EETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE--TT-H CS
  GDP_Man_Dehyd  2 iTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkgDltDs 64
                   +TG++  iG  ++++L +kg +  ++   +ss++    e++ ++ ++  + +++ +++DltD 
     EEA21517.1 14 VTGGSRGIGEAVVRRLAAKGCNLLIVYTSNSSTE--LTEKISSELSTTHNIHISSVQADLTDP 74
                   9****9****************998877666654..444444444444456899*******96 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.064
                    ----SHHHHHHHHHHHHHHHHHHH CS
  GDP_Man_Dehyd 147 fyPrsPYaaaKlyadwivvnyrea 170
                    ++ +s Ya +K++ + +++ + ++
     EEA21517.1 175 YEGQSVYAGTKAALEAMTRCWSRE 198
                    6789**************988654 PP

>> OMP_b-brl_3  Outer membrane protein beta-barrel family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.2   3.5e-06     0.011      35      94 ..      43     102 ..      35     123 .. 0.72

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 3.5e-06
  OMP_b-brl_3  35 pdgaeptnnslqrndndqknneytfqlDYtnplskkgkleaGykysfrntdsdfkyenld 94 
                  ++++e t+++ ++ ++  ++++ ++q+D t p++ + k+ aG+k+ + + +   ++++++
   EEA21517.1  43 NSSTELTEKISSELSTTHNIHISSVQADLTDPVGATPKIVAGAKAFYKSYTARSRSSKEE 102
                  33444555566666667789*************************999988888776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (308 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       475  (0.0264934); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 2117.36
//
Query:       EEA21518.1  [L=161]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.4e-15   54.8   1.4    1.1e-14   54.4   1.4    1.2  1  MAPEG     MAPEG family
  ------ inclusion threshold ------
      0.091   12.8   0.3      0.091   12.8   0.3    2.2  2  BTP       Chlorhexidine efflux transporter


Domain annotation for each model (and alignments):
>> MAPEG  MAPEG family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.4   1.4   1.2e-18   1.1e-14       4     128 ..      15     155 ..      12     157 .. 0.85

  Alignments for each domain:
  == domain 1  score: 54.4 bits;  conditional E-value: 1.2e-18
                 HHHHHHHHHHHHHHHHHHHHHHTT--SS---S.......................SH....HHHHHHHHHHHHHHHHHHHHHHHHHHHHH.T-HHHHHH CS
       MAPEG   4 yagllallllllslivvkerrkakiaigegkana.................pralddklppklqrairahgNflEyvplfllavllaeltgaetglaal 85 
                 y+ +l l++++ ++ +++ r  +  a  + + n+                  r++      + +r + ah+N++E++ +f+  ++l+ +++ ++g+++l
  EEA21518.1  15 YTSALLLWNYTYAYMLTSPRILKIRAGMDHNTNPrydlvkygeravaegkiTRKQLL----QMERSASAHANTIETFAFFATTIVLMNVAKLDAGTINL 109
                 788999999999999999999877766666555588888877777774444444444....8888*************************9******** PP

                 HHHHHHHHHHHHHHHH..HH-...SGGGHHHHHHHHHHHHHHHHHH CS
       MAPEG  86 laaafvvaRvlhalgy..iag.gpppgRslgflltllvllvlslla 128
                 +++a+ + R+ ++ +y  i++ + +++Rs ++ ++ + ++++++ a
  EEA21518.1 110 VGLAYSIFRIGYTQAYvhIEDhKLSFIRSALWHFGNFSCFYGIWCA 155
                 *************99977777999******************9986 PP

>> BTP  Chlorhexidine efflux transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   1.3     0.038   3.4e+02      43      56 ..      15      28 ..       2      29 .. 0.73
   2 ?   12.8   0.3     1e-05     0.091       8      54 ..      79     125 ..      76     132 .. 0.94

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.038
         BTP 43 lslfalvwnfvyNl 56
                 +   l+wn+ y +
  EEA21518.1 15 YTSALLLWNYTYAY 28
                5566799****975 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 1e-05
         BTP   8 lHallFElglllllvpllawllgvslleagvldiglslfalvwnfvy 54 
                 +Ha + E ++ + ++ +l+ + +++++++ +++++ s+f + ++ +y
  EEA21518.1  79 AHANTIETFAFFATTIVLMNVAKLDAGTINLVGLAYSIFRIGYTQAY 125
                 6999****************************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (161 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       495  (0.0276089); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.41u 0.24s 00:00:00.64 Elapsed: 00:00:00.42
# Mc/sec: 1145.74
//
Query:       EEA21519.1  [L=569]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-37  130.0   0.0    1.7e-37  129.4   0.0    1.3  1  Arylsulfotran_2  Arylsulfotransferase (ASST)
    6.2e-07   28.6   0.0    2.1e-06   26.9   0.0    1.8  2  Arylsulfotrans   Arylsulfotransferase (ASST)
    0.00037   20.2   0.6      0.066   12.8   0.1    3.4  4  PQQ_2            PQQ-like domain


Domain annotation for each model (and alignments):
>> Arylsulfotran_2  Arylsulfotransferase (ASST)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  129.4   0.0   2.9e-41   1.7e-37       2     293 ..     119     391 ..     118     397 .. 0.91

  Alignments for each domain:
  == domain 1  score: 129.4 bits;  conditional E-value: 2.9e-41
  Arylsulfotran_2   2 vqlLkdesvitnwegdglkGfGyGtltildssyeeiwkvtldgdfvtpdsesesyidhHeseitedgtilvtavnvtqadltsvggekdgwvld 95 
                      vq+  +++ +t+w ++    fG G  ++ldssy e + vt  g              +H++++t + t l++a+   +adl+ +gg  dgw+ld
       EEA21519.1 119 VQTFRGQDYLTYWTKEP---FGPGRYAMLDSSYTERFIVTPVG---------MVIDSLHDFTVTRHDTALIAAHYKRRADLSAIGGAVDGWILD 200
                      79999**********95...9**********************.........556679************************************ PP

  Arylsulfotran_2  96 sliyeidietnevlfrwSalehvdeipleeskaplgdfgrdeskpedyfHlNsvekfedgdyLiSlrelsslflirpkegkvlWqlqGpkggdf 189
                      ++++eidi t+  l++w a ehv   ++    ++l + +++e++p+dyfHl+ v++   gdyL+S+ ++ s++ + +++g+v W+l G    df
       EEA21519.1 201 GIFQEIDIVTGTLLYEWRAAEHVPIPNTL---KALDNGEGTEDQPFDYFHLSGVDQGPSGDYLVSAGHMRSVMSVDASTGQVQWNLGGR-ANDF 290
                      **********************9544444...5999999**************************************************.8888 PP

  Arylsulfotran_2 190 el....dnstfsrQHdariveetedkivislfnNentdtnerepttglildvdlq.nkevtllrklkdaedeissvsqGsyqllpn.ghvlvee 277
                      +     + ++f++ H+ar +    ++ +i + +       + ++++++ ++++++ +++ + lr+++    e + +s G +q+    g+vl+ +
       EEA21519.1 291 RGfdgrPIVDFTWPHNARWS----ENGTIMVMDK-----GGSAAGRSRGMTIQINpHTSQAVLRQVYRGPVEPKEPSDGDMQISQDtGNVLISW 375
                      766668889**********9....9********9.....577777777777777777777888999978888999********9878******* PP

  Arylsulfotran_2 278 gsigrveeydangkiv 293
                      g    + e++a+gk+ 
       EEA21519.1 376 GGGCGLSEFTADGKLL 391
                      **************86 PP

>> Arylsulfotrans  Arylsulfotransferase (ASST)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.9   0.0   3.5e-10   2.1e-06      28     215 ..      93     286 ..      72     292 .. 0.73
   2 ?   -2.6   0.0      0.32   1.9e+03      29      45 ..     497     513 ..     491     519 .. 0.78

  Alignments for each domain:
  == domain 1  score: 26.9 bits;  conditional E-value: 3.5e-10
  Arylsulfotrans  28 knnlivDtkGevrWyldqdkisdnk.lkrlkngk.llilsg.....qklaefdllGrvikeyrlpggyidlhHdivelpngnllvlvaeenykrk 115
                     +++ i+D++Ge++W  + + + +n  ++ ++  + l++ ++      ++a +d    + +  +  g +id  Hd +++ +++ l+++  ++  + 
      EEA21519.1  93 RSPAIYDQDGELIWQERRNVPTQNLrVQTFRGQDyLTYWTKepfgpGRYAMLDSSYTERFIVTPVGMVIDSLHDFTVTRHDTALIAAHYKRRADL 187
                     67899*********999888888754333333330333333475554444444444433333333445999**************9994444433 PP

  Arylsulfotrans 116 ...dgkkvktveDtii.evd.ktGkvvkewdlakiLdpyrdallkaakapfgdiagvg.agrdWlHiNsveydekddsiivSsRhqsavvkidyr 204
                         g     + D i  e+d  tG ++ ew++a++  p  ++l      ++++ +g++ +  d +H  +v+  +  ++ +vS  h+  v+ +d +
      EEA21519.1 188 saiGGAVDGWILDGIFqEIDiVTGTLLYEWRAAEHV-PIPNTLK-----ALDNGEGTEdQPFDYFHLSGVDQGP-SGDYLVSAGHMRSVMSVDAS 275
                     566668888899999758******************.7777333.....3445555443889*********877.667789999999******** PP

  Arylsulfotrans 205 tkkvkWilgdk 215
                     t++v+W lg +
      EEA21519.1 276 TGQVQWNLGGR 286
                     *******9965 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 0.32
  Arylsulfotrans  29 nnlivDtkGevrWyldq 45 
                     ++ ++D++G+v  y+d 
      EEA21519.1 497 RVAAIDQQGQVLGYTDD 513
                     56789999999999875 PP

>> PQQ_2  PQQ-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    3.3   0.0    0.0086        51      91     116 ..      98     121 ..      84     145 .. 0.82
   2 !   12.8   0.1   1.1e-05     0.066      25      61 ..     247     282 ..     200     288 .. 0.76
   3 ?   -2.0   0.0      0.35   2.1e+03      41      41 ..     374     374 ..     306     417 .. 0.52
   4 ?   -2.0   0.0      0.36   2.1e+03     176     203 ..     498     526 ..     491     558 .. 0.55

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.0086
       PQQ_2  91 ldaedGkrlWstqqrseepaelrssa 116
                 +d +dG++ W+ ++r+ ++++lr+++
  EEA21519.1  98 YD-QDGELIWQ-ERRNVPTQNLRVQT 121
                 44.99******.99998999988876 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 1.1e-05
       PQQ_2  25 lgggvsravlsggtlfvatgggrlvaldaatGkvlWe 61 
                 + +gv+++  sg++l++a+ ++ ++++da+tG+v W+
  EEA21519.1 247 HLSGVDQGP-SGDYLVSAGHMRSVMSVDASTGQVQWN 282
                 678886665.**************************6 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 0.35
       PQQ_2  41 v 41 
                 +
  EEA21519.1 374 S 374
                 1 PP

  == domain 4  score: -2.0 bits;  conditional E-value: 0.36
       PQQ_2 176 Vyassgqgrllal.dlatgrrlwskeiss 203
                 V a+ +qg++l + d  + ++ w+ +  s
  EEA21519.1 498 VAAIDQQGQVLGYtDDVEWQQAWTGSELS 526
                 55555555544443444444345444322 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (569 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       287  (0.0160076); expected 358.6 (0.02)
Passed bias filter:                      270  (0.0150594); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 3900.79
//
Query:       EEA21520.1  [L=455]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.1e-34  119.3   0.0    2.9e-34  118.8   0.0    1.1  1  Arylsulfotran_2  Arylsulfotransferase (ASST)
    2.9e-05   23.2   0.1    9.9e-05   21.4   0.0    1.8  2  Arylsulfotrans   Arylsulfotransferase (ASST)
      0.006   16.2   0.6      0.049   13.2   0.1    2.7  3  PQQ_2            PQQ-like domain


Domain annotation for each model (and alignments):
>> Arylsulfotran_2  Arylsulfotransferase (ASST)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.8   0.0   4.9e-38   2.9e-34      58     293 ..      49     277 ..      36     283 .. 0.91

  Alignments for each domain:
  == domain 1  score: 118.8 bits;  conditional E-value: 4.9e-38
  Arylsulfotran_2  58 dhHeseitedgtilvtavnvtqadltsvggekdgwvldsliyeidietnevlfrwSalehvdeipleeskaplgdfgrdeskpedyfHlNsvek 151
                       +H++++t + t l++a+   +adl+ +gg  dgw+ld++++eidi t+  l++w a ehv   ++    ++l + +++e++p+dyfHl+ v++
       EEA21520.1  49 SLHDFTVTRHDTALIAAHYKRRADLSAIGGAVDGWILDGIFQEIDIVTGTLLYEWRAAEHVPIPNTL---KALDNGEGTEDQPFDYFHLSGVDQ 139
                      58**********************************************************9544444...5999999***************** PP

  Arylsulfotran_2 152 fedgdyLiSlrelsslflirpkegkvlWqlqGpkggdfel....dnstfsrQHdariveetedkivislfnNentdtnerepttglildvdlq. 240
                         gdyL+S+ ++ s++ + +++g+v W+l G    df+     + ++f++ H+ar +    ++ +i + +       + ++++++ ++++++ 
       EEA21520.1 140 GPSGDYLVSAGHMRSVMSVDASTGQVQWNLGGR-ANDFRGfdgrPIVDFTWPHNARWS----ENGTIMVMDK-----GGSAAGRSRGMTIQINp 223
                      *********************************.8888766668889**********9....9********9.....57777777777777777 PP

  Arylsulfotran_2 241 nkevtllrklkdaedeissvsqGsyqllpn.ghvlveegsigrveeydangkiv 293
                      +++ + lr+++    e + +s G +q+    g+vl+ +g    + e++a+gk+ 
       EEA21520.1 224 HTSQAVLRQVYRGPVEPKEPSDGDMQISQDtGNVLISWGGGCGLSEFTADGKLL 277
                      7777888999978888999********9878*********************86 PP

>> Arylsulfotrans  Arylsulfotransferase (ASST)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0   1.7e-08   9.9e-05      89     215 ..      47     172 ..      36     178 .. 0.80
   2 ?   -2.1   0.1      0.23   1.4e+03      29      45 ..     383     399 ..     376     407 .. 0.79

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 1.7e-08
  Arylsulfotrans  89 idlhHdivelpngnllvlvaeenykrk...dgkkvktveDtii.evd.ktGkvvkewdlakiLdpyrdallkaakapfgdiagvg.agrdWlHiN 177
                     id  Hd +++ +++ l+++  ++  +     g     + D i  e+d  tG ++ ew++a++  p  ++l      ++++ +g++ +  d +H  
      EEA21520.1  47 IDSLHDFTVTRHDTALIAAHYKRRADLsaiGGAVDGWILDGIFqEIDiVTGTLLYEWRAAEHV-PIPNTLK-----ALDNGEGTEdQPFDYFHLS 135
                     566799999999999999984444333556667778889999658******************.7777333.....3445555443889****** PP

  Arylsulfotrans 178 sveydekddsiivSsRhqsavvkidyrtkkvkWilgdk 215
                     +v+  +  ++ +vS  h+  v+ +d +t++v+W lg +
      EEA21520.1 136 GVDQGP-SGDYLVSAGHMRSVMSVDASTGQVQWNLGGR 172
                     ***877.667789999999***************9965 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.23
  Arylsulfotrans  29 nnlivDtkGevrWyldq 45 
                     ++ ++D++G+v  y+d 
      EEA21520.1 383 RVAAIDQQGQVLGYTDD 399
                     56799999999999875 PP

>> PQQ_2  PQQ-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.2   0.1   8.1e-06     0.049      25      61 ..     133     168 ..      86     174 .. 0.76
   2 ?   -1.4   0.0      0.24   1.4e+03      41      41 ..     260     260 ..     190     305 .. 0.51
   3 ?   -1.5   0.0      0.26   1.6e+03     176     203 ..     384     412 ..     376     444 .. 0.55

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 8.1e-06
       PQQ_2  25 lgggvsravlsggtlfvatgggrlvaldaatGkvlWe 61 
                 + +gv+++  sg++l++a+ ++ ++++da+tG+v W+
  EEA21520.1 133 HLSGVDQGP-SGDYLVSAGHMRSVMSVDASTGQVQWN 168
                 678886665.**************************6 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.24
       PQQ_2  41 v 41 
                 +
  EEA21520.1 260 S 260
                 1 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 0.26
       PQQ_2 176 Vyassgqgrllal.dlatgrrlwskeiss 203
                 V a+ +qg++l + d  + ++ w+ +  s
  EEA21520.1 384 VAAIDQQGQVLGYtDDVEWQQAWTGSELS 412
                 55555555544444444444345444333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (455 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       298  (0.0166211); expected 358.6 (0.02)
Passed bias filter:                      279  (0.0155614); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 3219.75
//
Query:       EEA21521.1  [L=1499]
Description: chromatin structure remodeling complex protein RSC3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.6e-10   39.0   0.5    1.4e-09   38.0   0.5    1.6  1  DUF659         Protein of unknown function (DUF 659)
    2.5e-06   26.7   0.0    7.5e-06   25.2   0.0    1.8  1  Fungal_trans   Fungal specific transcription factor domain
    0.00012   21.7   0.3     0.0013   18.4   0.1    2.5  2  Dimer_Tnp_hAT  hAT family C-terminal dimerisation region
  ------ inclusion threshold ------
        5.1    5.8  10.7         44    2.7   0.0    2.5  2  Presenilin     Presenilin


Domain annotation for each model (and alignments):
>> DUF659  Protein of unknown function (DUF 659)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.0   0.5   3.2e-13   1.4e-09       1     144 [.      53     205 ..      53     218 .. 0.82

  Alignments for each domain:
  == domain 1  score: 38.0 bits;  conditional E-value: 3.2e-13
      DUF659   1 PsseeLrgtlLqeeveeikkkvkeikkswektgcsillDgwtdkkgrslinflvscpkGtvFlksvdassekktaeylaelldkvieevgaen...... 93 
                 P+++++ g+lL e ++e   ++k+i    + ++++i++D+++++++++++ +++++p+++      d+++e+ +a+++ e l + +e++ a+       
  EEA21521.1  53 PDRHRIGGSLLTELYTES--YTKTIGIWRQIQHLNITVDETSNINHQRVMVITITTPQRSWLYCLKDMENERLNAKNITEWLLHQLEALLATLfdgdid 149
                 89999*********9998..4554444445577**************************9999999***********9999999999855544444455 PP

      DUF659  94 ...Vvqvitdnasnykkagklleekyp..tifwtpcaahclnlmledilklkwvke 144
                    + +  td+ s ++ +++ l++k p  + f++pc +h+l+l+++d+l +k  + 
  EEA21521.1 150 wkcINSLSTDTCSTMRLVWEILQRKSPlqHAFMIPCDSHGLQLIFKDLLDMKVSQA 205
                 555********************8765328*******************9765443 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   0.0   1.7e-09   7.5e-06     114     189 ..    1027    1096 ..    1007    1144 .. 0.88

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 1.7e-09
  Fungal_trans  114 erhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcdd 189 
                    +r +g   ++   lgLhr +++ +      ++ + +e+r+R   a F lDk++a+ lGrpp + ++  ++++P d 
    EEA21521.1 1027 WRKLGDLSTIIFALGLHRPKPDPS------VPLFLIEIRKRAMSAGFALDKQLATLLGRPPRIAYQYCDIQYPLDL 1096
                    6666777777789***********......*******************************669999999999876 PP

>> Dimer_Tnp_hAT  hAT family C-terminal dimerisation region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.1     3e-07    0.0013      18      83 ..     394     459 ..     380     461 .. 0.90
   2 ?   -0.2   0.0      0.19   8.6e+02      33      53 ..    1222    1242 ..    1192    1245 .. 0.76

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 3e-07
                    ..--HHHHHHHTTTTSHHHHHHHHHHHTS-S-TTTTHHHHHHTHHHHH-TTT---HHHHHHHHHHH CS
  Dimer_Tnp_hAT  18 sefdvlewwkensskyPnlsklardvLsipvssaasErsFstlgkvllesrnsleplnveallcie 83 
                    ++ +++++  ++ +  P l  +a ++    + s+++Er+Fs +   +++ rn+l  + ve+ll+++
     EEA21521.1 394 TKEKIVQFRAQEADIAPKLASFANRLIHTVANSVTAERAFSLMNLQHTKIRNRLSVEQVEKLLFLQ 459
                    56789999999999**************************************************97 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.19
                     SHHHHHHHHHHHTS-S-TTTT CS
  Dimer_Tnp_hAT   33 yPnlsklardvLsipvssaas 53  
                      + l ++ar++Ls  vs +++
     EEA21521.1 1222 KDKLIQAARKMLSTLVSWVSA 1242
                     567999***********9986 PP

>> Presenilin  Presenilin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.0    0.0099        44     328     345 ..    1207    1224 ..    1157    1233 .. 0.90
   2 ?   -1.4  12.2      0.17   7.4e+02     235     295 ..    1357    1436 ..    1338    1460 .. 0.35

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.0099
  Presenilin  328 DFiFYSvLvgkAalsgdl 345 
                  DFi YSvL+ ++  ++d 
  EEA21521.1 1207 DFILYSVLIKRTGEHKDK 1224
                  9********999886665 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.17
  Presenilin  235 seeeeeaekkkeeasesskeeeseeesseksaqsse.....................................seeeseeesseaessaeesseeke 294 
                  + ++e+++++ +++++++++++++++         e                                     +        + ++++ ++++++++
  EEA21521.1 1357 HGHREKSQQQPQQKQHQQQQQKQKQN---------EvvqdpsvlryaspsapsaplapstehfpvssathlqqQ--------EITPDT-QQQQNQHQ 1435
                  11111111111111111111111111.........112233344455566666666665555554322222110........111111.11111111 PP

  Presenilin  295 s 295 
                  +
  EEA21521.1 1436 H 1436
                  1 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1499 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1777  (0.0991132); expected 358.6 (0.02)
Passed bias filter:                      660  (0.0368119); expected 358.6 (0.02)
Passed Vit filter:                        72  (0.00401584); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.09u 0.30s 00:00:01.39 Elapsed: 00:00:00.46
# Mc/sec: 9862.24
//
Query:       EEA21522.1  [L=1667]
Description: UDP-N-acetylglucosaminyltransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
     1e-104  350.6   1.1    5.6e-51  173.4   0.1    4.1  2  Glyco_transf_41  Glycosyl transferase family 41
    5.6e-18   63.9  10.6    1.2e-05   24.9   0.1    6.4  6  TPR_1            Tetratricopeptide repeat
    2.9e-15   55.1  13.0      0.006   16.6   0.1    6.1  6  TPR_2            Tetratricopeptide repeat
    8.7e-14   50.9  14.6    1.9e-05   24.2   0.2    6.4  6  TPR_11           TPR repeat
    4.3e-11   42.1   5.4      0.088   13.1   0.0    5.7  5  TPR_8            Tetratricopeptide repeat
    5.2e-10   39.0   5.7       0.02   15.2   0.0    5.8  5  TPR_17           Tetratricopeptide repeat
      7e-07   29.7  13.5     0.0035   17.8   0.7    4.6  5  TPR_19           Tetratricopeptide repeat
    7.2e-07   29.5  11.8      0.058   14.2   0.0    5.7  5  TPR_14           Tetratricopeptide repeat
    2.5e-06   27.7   9.3      0.039   14.2   0.4    4.6  4  TPR_12           Tetratricopeptide repeat
    1.9e-05   24.3  15.3       0.64   10.0   0.2    5.7  5  TPR_10           Tetratricopeptide repeat
    2.6e-05   24.8  15.6       0.23   12.2   1.4    4.5  4  TPR_16           Tetratricopeptide repeat
     0.0022   17.9   9.1       0.55   10.4   0.1    5.2  6  TPR_7            Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.088   13.0   7.2       0.37   11.0   0.1    3.6  3  TPR_9            Tetratricopeptide repeat
       0.36   11.1   2.5       0.82    9.9   0.4    2.6  2  ANAPC3           Anaphase-promoting complex, cyclosome, subun


Domain annotation for each model (and alignments):
>> Glyco_transf_41  Glycosyl transferase family 41
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  166.6   0.1     5e-52   6.4e-49       1     132 [.    1227    1357 ..    1227    1422 .. 0.90
   2 !  173.4   0.1   4.4e-54   5.6e-51     283     471 .]    1433    1654 ..    1417    1654 .. 0.83

  Alignments for each domain:
  == domain 1  score: 166.6 bits;  conditional E-value: 5e-52
  Glyco_transf_41    1 lriGyvssdfgnhPtshlmqsiPglhdrekvevfcyalspddgttfrkkiakeaehfvdlsqiqcngkaadrikedGihilvnmnGytkGar 92  
                       l++Gyvssdf nhP +hlmqs+ g+h+ ++v+ +cya ++ d++t+r++i +e+ +f d s  + + +  ++i +dGihilvn+nGyt+Gar
       EEA21522.1 1227 LKVGYVSSDFNNHPLAHLMQSVFGFHNPNRVKAYCYATTASDNSTHRQQIERESPQFHDASSWPVD-RLVKQIVSDGIHILVNLNGYTRGAR 1317
                       79************************************************************9986.67899******************** PP

  Glyco_transf_41   93 neifalrPaPiqvmwlGyPgtsGasfmdyiitdkvtsPle 132 
                       ne+fa rPaPiq+ ++G+ gt Ga++ dyi++d+ + P +
       EEA21522.1 1318 NEVFAARPAPIQMSFMGFAGTLGAEWCDYILADELSIPRD 1357
                       *********************************9988855 PP

  == domain 2  score: 173.4 bits;  conditional E-value: 4.4e-54
  Glyco_transf_41  283 glPedaivycnfnqlykidPstlemwvnilkrvPnsvlwllrfPavGeanvlataaelgl..ekeriifsnvaakeehvrrGqladvcldtP 372 
                       +lP+dai+  nfnqlyki+P+t+++w++il  +P++vlwllrfP  Ge+n++++a++ +    ++riif++va+k+ h+ r q+ d+ ldtP
       EEA21522.1 1433 TLPDDAIILGNFNQLYKIEPTTFRTWLRILSDIPKAVLWLLRFPELGEQNLKDCAVQWANeeIASRIIFTDVAPKQAHIARAQVVDLFLDTP 1524
                       69****************************************************99986522479*************************** PP

  Glyco_transf_41  373 lcnGhttgmdvlwaGtPvvtlpl..etlasrvaasqlatl.........GvpeliaksreeyediavklGtdkey................. 436 
                        cn htt+ d+lw+GtP++t+p     + sr+a+s l +            +el+a s e+y+  a +l +d  y                 
       EEA21522.1 1525 ECNAHTTAADILWSGTPMLTFPRykYKMCSRMASSILSSAlpdteagrqARNELVAISDEDYRAKASRLCRDLRYhpagvettgghsrvghc 1616
                       **********************7225689*****9997632333332223579*************99988876522222222222222222 PP

  Glyco_transf_41  437 ...lkairakvwkaraestlfnvkkyaadleklykklw 471 
                          l ++r  ++++r +s+lf+++++++dle+ y+k+w
       EEA21522.1 1617 tgrLVELRRMLFTHRWQSRLFDTRRWVSDLENAYEKVW 1654
                       22256789999**************************9 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.3   0.0    0.0069       8.8       8      31 ..     562     585 ..     562     588 .. 0.89
   2 !   15.6   0.0   8.4e-06     0.011       2      34 .]     590     622 ..     589     622 .. 0.94
   3 !    7.8   0.3    0.0023         3       7      30 ..     732     755 ..     730     758 .. 0.92
   4 ?    1.0   0.0      0.33   4.2e+02      19      34 .]     927     942 ..     925     942 .. 0.90
   5 !    9.7   0.1   0.00061      0.79       3      34 .]     945     976 ..     943     976 .. 0.92
   6 !   24.9   0.1   9.7e-09   1.2e-05       3      34 .]     979    1010 ..     978    1010 .. 0.97

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0069
                 HHHHHHTT-HHHHHHHHHHHHHHS CS
       TPR_1   8 GnayfklgkydeAleyyekALeln 31 
                 G + + lg+y++A   y++ +  +
  EEA21522.1 562 GCLAYGLGDYQKATRWYSRIIARD 585
                 778899*************99876 PP

  == domain 2  score: 15.6 bits;  conditional E-value: 8.4e-06
                 HHHHHHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1   2 kalynlGnayfklgkydeAleyyekALelnPnn 34 
                 +a  nl+++++ l + +eA ++  +A++l+P++
  EEA21522.1 590 EAISNLAATFLALDQKEEARQHWLRAVKLRPSY 622
                 6789***************************97 PP

  == domain 3  score: 7.8 bits;  conditional E-value: 0.0023
                 HHHHHHHTT-HHHHHHHHHHHHHH CS
       TPR_1   7 lGnayfklgkydeAleyyekALel 30 
                 +Gn+++ lg+   A +++e+A+ +
  EEA21522.1 732 KGNMLYALGDNAGAAAAFEEAILI 755
                 7********************976 PP

  == domain 4  score: 1.0 bits;  conditional E-value: 0.33
                 HHHHHHHHHHHHSTTH CS
       TPR_1  19 eAleyyekALelnPnn 34 
                  Al yy+  L+l+P++
  EEA21522.1 927 LALSYYSYGLTLDPKH 942
                 599***********86 PP

  == domain 5  score: 9.7 bits;  conditional E-value: 0.00061
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1   3 alynlGnayfklgkydeAleyyekALelnPnn 34 
                  + nlG +    g++  A+  ye A++ + n+
  EEA21522.1 945 LYTNLGSLWKDIGQLHAAIRMYELAVQYDGNF 976
                 599***********************998775 PP

  == domain 6  score: 24.9 bits;  conditional E-value: 9.7e-09
                  HHHHHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1    3 alynlGnayfklgkydeAleyyekALelnPnn 34  
                  al nl+na    g+ ++A+ yy++A+++nP++
  EEA21522.1  979 ALANLANAVKDAGRINDAIVYYKRAVKVNPDF 1010
                  899***************************97 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.2   0.1    0.0011       1.4       8      31 ..     562     585 ..     562     588 .. 0.90
   2 !   16.6   0.1   4.7e-06     0.006       2      33 ..     590     621 ..     589     622 .. 0.93
   3 !   12.7   0.3   8.5e-05      0.11       6      31 ..     731     756 ..     728     758 .. 0.91
   4 ?   -1.4   0.0       2.8   3.6e+03      20      34 .]     928     942 ..     926     942 .. 0.88
   5 ?    5.3   0.1      0.02        25       2      33 ..     944     975 ..     943     976 .. 0.91
   6 !   15.3   0.0   1.2e-05     0.016       3      33 ..     979    1009 ..     978    1010 .. 0.95

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0011
       TPR_2   8 GlayyklgdyeeAleafekAleld 31 
                 G+++y lgdy++A +++ + ++ d
  EEA21522.1 562 GCLAYGLGDYQKATRWYSRIIARD 585
                 7899**************999876 PP

  == domain 2  score: 16.6 bits;  conditional E-value: 4.7e-06
       TPR_2   2 ealynlGlayyklgdyeeAleafekAleldPn 33 
                 ea  nl+   ++l++ eeA++++ +A++l P 
  EEA21522.1 590 EAISNLAATFLALDQKEEARQHWLRAVKLRPS 621
                 7889**************************97 PP

  == domain 3  score: 12.7 bits;  conditional E-value: 8.5e-05
       TPR_2   6 nlGlayyklgdyeeAleafekAleld 31 
                 + G+ +y+lgd + A++afe+A+ ++
  EEA21522.1 731 AKGNMLYALGDNAGAAAAFEEAILIA 756
                 78********************9875 PP

  == domain 4  score: -1.4 bits;  conditional E-value: 2.8
       TPR_2  20 AleafekAleldPnn 34 
                 Al ++   l ldP++
  EEA21522.1 928 ALSYYSYGLTLDPKH 942
                 89999999****986 PP

  == domain 5  score: 5.3 bits;  conditional E-value: 0.02
       TPR_2   2 ealynlGlayyklgdyeeAleafekAleldPn 33 
                  ++ nlG ++   g++  A++ +e A+++d n
  EEA21522.1 944 HLYTNLGSLWKDIGQLHAAIRMYELAVQYDGN 975
                 57899***********************9976 PP

  == domain 6  score: 15.3 bits;  conditional E-value: 1.2e-05
       TPR_2    3 alynlGlayyklgdyeeAleafekAleldPn 33  
                  al nl++a   +g+ ++A+ ++++A++ +P+
  EEA21522.1  979 ALANLANAVKDAGRINDAIVYYKRAVKVNPD 1009
                  799***************************8 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0      0.05        64       7      40 ..     568     601 ..     564     603 .. 0.91
   2 !   10.7   0.0   0.00025      0.32       9      30 ..     604     625 ..     599     629 .. 0.87
   3 !    8.1   0.4    0.0016         2       1      21 [.     733     753 ..     733     755 .. 0.96
   4 ?    3.1   0.1     0.062        79      17      36 ..     932     951 ..     926     955 .. 0.84
   5 !    8.4   0.5    0.0013       1.7       7      40 ..     956     989 ..     954     991 .. 0.91
   6 !   24.2   0.2   1.5e-08   1.9e-05       2      38 ..     985    1021 ..     984    1022 .. 0.92

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.05
      TPR_11   7 qGkyeeAieaYkkAlkldPdnaeayynLGlayyk 40 
                 +G+y +A  +Y++ ++ d   +ea +nL++++++
  EEA21522.1 568 LGDYQKATRWYSRIIARDARHVEAISNLAATFLA 601
                 7****************************99876 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 0.00025
      TPR_11   9 kyeeAieaYkkAlkldPdnaea 30 
                 + eeA +++ +A+kl+P++ ea
  EEA21522.1 604 QKEEARQHWLRAVKLRPSYFEA 625
                 569****************998 PP

  == domain 3  score: 8.1 bits;  conditional E-value: 0.0016
      TPR_11   1 GdayyeqGkyeeAieaYkkAl 21 
                 G+++y++G++ +A +a+++A+
  EEA21522.1 733 GNMLYALGDNAGAAAAFEEAI 753
                 9*******************9 PP

  == domain 4  score: 3.1 bits;  conditional E-value: 0.062
      TPR_11  17 YkkAlkldPdnaeayynLGl 36 
                 Y+  l ldP+ a +y nLG 
  EEA21522.1 932 YSYGLTLDPKHAHLYTNLGS 951
                 666799*************5 PP

  == domain 5  score: 8.4 bits;  conditional E-value: 0.0013
      TPR_11   7 qGkyeeAieaYkkAlkldPdnaeayynLGlayyk 40 
                  G++ +Ai  Y+ A+++d ++  a+ nL++a   
  EEA21522.1 956 IGQLHAAIRMYELAVQYDGNFDIALANLANAVKD 989
                 59****************************9865 PP

  == domain 6  score: 24.2 bits;  conditional E-value: 1.5e-08
      TPR_11    2 dayyeqGkyeeAieaYkkAlkldPdnaeayynLGlay 38  
                  +a  + G++++Ai  Yk+A+k +Pd+aea ++L++a+
  EEA21522.1  985 NAVKDAGRINDAIVYYKRAVKVNPDFAEAVCGLANAL 1021
                  566789****************************996 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0      0.16   2.1e+02       8      31 ..     562     585 ..     558     588 .. 0.81
   2 ?    5.3   0.0     0.021        26       3      33 ..     591     621 ..     589     622 .. 0.90
   3 ?    5.8   0.2     0.014        18       5      31 ..     730     756 ..     727     758 .. 0.90
   4 !   12.9   0.0   7.8e-05       0.1       1      33 [.     943     975 ..     943     976 .. 0.93
   5 !   13.1   0.0   6.9e-05     0.088       3      33 ..     979    1009 ..     978    1010 .. 0.94

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.16
                 HHHHHHTT-HHHHHHHHHHHHHHH CS
       TPR_8   8 gsiylklgdyeeAkeyyekaleld 31 
                 g++   lgdy++A  +y + +  d
  EEA21522.1 562 GCLAYGLGDYQKATRWYSRIIARD 585
                 58999********99998877666 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.021
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAkeyyekaleldpd 33 
                 a  nl+ + l l ++eeA +   +a++l+p+
  EEA21522.1 591 AISNLAATFLALDQKEEARQHWLRAVKLRPS 621
                 66799999*********************97 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.014
                 HHHHHHHHHTT-HHHHHHHHHHHHHHH CS
       TPR_8   5 ynlgsiylklgdyeeAkeyyekaleld 31 
                 + +g+ +  lgd   A +++e+a+ ++
  EEA21522.1 730 HAKGNMLYALGDNAGAAAAFEEAILIA 756
                 578999*****************9876 PP

  == domain 4  score: 12.9 bits;  conditional E-value: 7.8e-05
                 CCHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   1 aeayynlgsiylklgdyeeAkeyyekaleldpd 33 
                 a++y nlgs+ ++ g++++A+  ye a+++d +
  EEA21522.1 943 AHLYTNLGSLWKDIGQLHAAIRMYELAVQYDGN 975
                 689*************************99865 PP

  == domain 5  score: 13.1 bits;  conditional E-value: 6.9e-05
                  HHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8    3 ayynlgsiylklgdyeeAkeyyekaleldpd 33  
                  a+ nl+++ ++ g+++ A+ yy++a++ +pd
  EEA21522.1  979 ALANLANAVKDAGRINDAIVYYKRAVKVNPD 1009
                  6889**************************8 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.8   0.0   0.00087       1.1       2      34 .]     578     610 ..     577     610 .. 0.96
   2 ?   -2.6   0.0       7.6   9.8e+03       3      25 ..     613     635 ..     612     643 .. 0.78
   3 !   15.2   0.0   1.6e-05      0.02       6      33 ..     936     963 ..     931     964 .. 0.90
   4 ?    2.0   0.2      0.26   3.4e+02       1      32 [.     965     996 ..     965     997 .. 0.87
   5 !    9.5   0.1    0.0011       1.4       1      23 [.     999    1021 ..     999    1030 .. 0.93

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00087
      TPR_17   2 ylkaleldPnnadaynnLAelllknGdlmtArq 34 
                 y + +++d  +++a  nLA ++l + ++++Arq
  EEA21522.1 578 YSRIIARDARHVEAISNLAATFLALDQKEEARQ 610
                 7799***************************98 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 7.6
      TPR_17   3 lkaleldPnnadaynnLAelllk 25 
                 l+a++l P++++a   L +ll+ 
  EEA21522.1 613 LRAVKLRPSYFEAVEHLINLLCT 635
                 7999******9998888888874 PP

  == domain 3  score: 15.2 bits;  conditional E-value: 1.6e-05
      TPR_17   6 leldPnnadaynnLAelllknGdlmtAr 33 
                 l ldP++a +y+nL+ l++ +G+l  A+
  EEA21522.1 936 LTLDPKHAHLYTNLGSLWKDIGQLHAAI 963
                 789*********************9996 PP

  == domain 4  score: 2.0 bits;  conditional E-value: 0.26
      TPR_17   1 lylkaleldPnnadaynnLAelllknGdlmtA 32 
                 +y+ a+++d n   a+ nLA++ + +G+  +A
  EEA21522.1 965 MYELAVQYDGNFDIALANLANAVKDAGRINDA 996
                 5899999**************98888887776 PP

  == domain 5  score: 9.5 bits;  conditional E-value: 0.0011
      TPR_17    1 lylkaleldPnnadaynnLAell 23  
                  +y++a++ +P+ a+a + LA++l
  EEA21522.1  999 YYKRAVKVNPDFAEAVCGLANAL 1021
                  6********************98 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.2   6.9e-06    0.0089       3      46 ..     567     610 ..     565     632 .. 0.90
   2 ?   -1.3   0.5       2.6   3.3e+03       1      18 [.     736     753 ..     736     758 .. 0.84
   3 ?    4.2   0.4     0.049        62      10      57 ..     928     975 ..     925     983 .. 0.85
   4 !   17.8   0.7   2.8e-06    0.0035       5      59 ..     957    1011 ..     955    1014 .. 0.94
   5 !   13.3   0.0   7.2e-05     0.092       3      35 ..     989    1021 ..     988    1027 .. 0.95

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 6.9e-06
      TPR_19   3 aegdyaeAlalleqalqedpknaearllLAeallalgqldeAea 46 
                   gdy+ A + ++++++ d+ + ea  +LA   lal q +eA++
  EEA21522.1 567 GLGDYQKATRWYSRIIARDARHVEAISNLAATFLALDQKEEARQ 610
                 569***************************************98 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 2.6
      TPR_19   1 llaegdyaeAlalleqal 18 
                 l+a gd a A+a++e+a+
  EEA21522.1 736 LYALGDNAGAAAAFEEAI 753
                 67889**********995 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.049
      TPR_19  10 AlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpd 57 
                 Al+++++ l+ dpk+a +  +L  +    gql +A+++ + + + d +
  EEA21522.1 928 ALSYYSYGLTLDPKHAHLYTNLGSLWKDIGQLHAAIRMYELAVQYDGN 975
                 9999*********************99999999999998887777776 PP

  == domain 4  score: 17.8 bits;  conditional E-value: 2.8e-06
      TPR_19    5 gdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpdda 59  
                  g++ +A++++e a q+d + + a+++LA+a   +g++++A+   +++ + +pd a
  EEA21522.1  957 GQLHAAIRMYELAVQYDGNFDIALANLANAVKDAGRINDAIVYYKRAVKVNPDFA 1011
                  8999*********************************************999965 PP

  == domain 5  score: 13.3 bits;  conditional E-value: 7.2e-05
      TPR_19    3 aegdyaeAlalleqalqedpknaearllLAeal 35  
                  ++g+  +A+ ++++a + +p+ aea  +LA+al
  EEA21522.1  989 DAGRINDAIVYYKRAVKVNPDFAEAVCGLANAL 1021
                  689****************************98 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.1     0.059        76      14      42 ..     568     596 ..     558     598 .. 0.86
   2 !    9.3   0.5    0.0018       2.3       3      42 ..     591     630 ..     589     632 .. 0.89
   3 ?    4.3   0.4      0.07        89       6      28 ..     731     753 ..     726     758 .. 0.85
   4 ?    3.8   0.2       0.1   1.3e+02       7      42 ..     949     984 ..     943     986 .. 0.80
   5 !   14.2   0.0   4.5e-05     0.058       3      42 ..     979    1018 ..     977    1020 .. 0.90

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.059
      TPR_14  14 lGdpdeAiallrralalaPddaeawllla 42 
                 lGd+++A + + r++a++  + ea   la
  EEA21522.1 568 LGDYQKATRWYSRIIARDARHVEAISNLA 596
                 8*****************99999977766 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.0018
      TPR_14   3 allalaeallalGdpdeAiallrralalaPddaeawllla 42 
                 a   la+ +lal++ +eA+++  ra++l P+  ea  +l 
  EEA21522.1 591 AISNLAATFLALDQKEEARQHWLRAVKLRPSYFEAVEHLI 630
                 556699****************************999986 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.07
      TPR_14   6 alaeallalGdpdeAiallrral 28 
                 a +  l+alGd ++A+a++++a+
  EEA21522.1 731 AKGNMLYALGDNAGAAAAFEEAI 753
                 5678899**************97 PP

  == domain 4  score: 3.8 bits;  conditional E-value: 0.1
      TPR_14   7 laeallalGdpdeAiallrralalaPddaeawllla 42 
                 l+++    G++ +Ai++++ a++ + +++ a+  la
  EEA21522.1 949 LGSLWKDIGQLHAAIRMYELAVQYDGNFDIALANLA 984
                 666677789************998888777777776 PP

  == domain 5  score: 14.2 bits;  conditional E-value: 4.5e-05
      TPR_14    3 allalaeallalGdpdeAiallrralalaPddaeawllla 42  
                  al+ la a   +G+  +Ai +++ra++ +Pd+aea   la
  EEA21522.1  979 ALANLANAVKDAGRINDAIVYYKRAVKVNPDFAEAVCGLA 1018
                  56778999999************************98887 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.4     3e-05     0.039       8      76 ..     559     620 ..     555     621 .. 0.87
   2 !    6.3   0.1    0.0091        12       8      32 ..     731     755 ..     716     759 .. 0.56
   3 ?    4.5   0.1     0.034        44      42      72 ..     940     970 ..     926     975 .. 0.83
   4 !    7.5   0.5    0.0038       4.8       4      74 ..     944    1006 ..     941    1009 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 3e-05
      TPR_12   8 nlaavlrr.lgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                  l+ +l++ lg+y++A +++ + +++        h   +++  nL+ +++al++ eeA+++  +a+++++
  EEA21522.1 559 LLGGCLAYgLGDYQKATRWYSRIIARD-----ARH---VEAISNLAATFLALDQKEEARQHWLRAVKLRP 620
                 499999555**************7777.....667...89********************9999988875 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0091
      TPR_12   8 nlaavlrrlgrydeAlellekalei 32 
                   +++l++lg+ + A + +e+a+ i
  EEA21522.1 731 AKGNMLYALGDNAGAAAAFEEAILI 755
                 3566666666666666666666555 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.034
      TPR_12  42 pltattlrnLgrlyralgryeeAlelleeal 72 
                 p  a  + nLg l    g++ +A++++e a+
  EEA21522.1 940 PKHAHLYTNLGSLWKDIGQLHAAIRMYELAV 970
                 6679999999999889999999999999876 PP

  == domain 4  score: 7.5 bits;  conditional E-value: 0.0038
      TPR_12    4 talnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealai 74  
                   +++nl+++    g+++ A++++e a++      G       ++l nL+ +   +gr  +A+ ++++a+++
  EEA21522.1  944 HLYTNLGSLWKDIGQLHAAIRMYELAVQYD----GNFD----IALANLANAVKDAGRINDAIVYYKRAVKV 1006
                  567778888888888888888888884444....4333....68999999999999999999999999875 PP

>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0      0.72   9.2e+02      10      31 ..     563     584 ..     562     590 .. 0.81
   2 !    6.2   0.2    0.0077       9.9       4      32 ..     591     619 ..     588     619 .. 0.92
   3 !    7.3   0.4    0.0035       4.5       9      30 ..     733     754 ..     730     756 .. 0.92
   4 !    7.2   0.1    0.0038       4.9       2      30 ..     943     971 ..     942     972 .. 0.92
   5 !   10.0   0.2    0.0005      0.64       4      30 ..     979    1005 ..     978    1007 .. 0.94

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.72
      TPR_10  10 nalrqrgrydeAealleealai 31 
                 ++ + +g+y++A +++ + +a+
  EEA21522.1 563 CLAYGLGDYQKATRWYSRIIAR 584
                 566889*********9888876 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.0077
      TPR_10   4 slnNLanalrqrgrydeAealleealair 32 
                 + +NLa++  ++ + +eA+++  +a+ +r
  EEA21522.1 591 AISNLAATFLALDQKEEARQHWLRAVKLR 619
                 789*******************9999875 PP

  == domain 3  score: 7.3 bits;  conditional E-value: 0.0035
      TPR_10   9 analrqrgrydeAealleeala 30 
                 +n+l+++g+ ++A a +eea+ 
  EEA21522.1 733 GNMLYALGDNAGAAAAFEEAIL 754
                 89******************96 PP

  == domain 4  score: 7.2 bits;  conditional E-value: 0.0038
      TPR_10   2 AsslnNLanalrqrgrydeAealleeala 30 
                 A  ++NL+ +  + g++++A +++e a++
  EEA21522.1 943 AHLYTNLGSLWKDIGQLHAAIRMYELAVQ 971
                 5679*********************9986 PP

  == domain 5  score: 10.0 bits;  conditional E-value: 0.0005
      TPR_10    4 slnNLanalrqrgrydeAealleeala 30  
                  +l NLana  + gr ++A  ++++a+ 
  EEA21522.1  979 ALANLANAVKDAGRINDAIVYYKRAVK 1005
                  689**********************97 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.2   1.4   0.00018      0.23       4      65 ..     562     620 ..     559     622 .. 0.89
   2 ?    6.2   0.8     0.013        17      40      61 ..     732     753 ..     731     759 .. 0.78
   3 ?    1.3   0.0      0.43   5.5e+02      15      61 ..     927     970 ..     924     977 .. 0.85
   4 !   12.1   0.1   0.00018      0.23       2      44 ..     982    1021 ..     981    1024 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00018
      TPR_16   4 araalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraalraap 65 
                 + +a+ +gdy++A + + + ++rd    +++eA  +l+  +l++   +eA++  ++a++  p
  EEA21522.1 562 GCLAYGLGDYQKATRWYSRIIARD---ARHVEAISNLAATFLALDQKEEARQHWLRAVKLRP 620
                 7899********************...************************55555557766 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.013
      TPR_16  40 lgdaalrqgrlaeAaalyraal 61 
                 +g++++++g+ a+Aaa++++a+
  EEA21522.1 732 KGNMLYALGDNAGAAAAFEEAI 753
                 5788889999999998888875 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.43
      TPR_16  15 dAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraal 61 
                  A+ ++   l +d   P +a+ + +lg ++   g l +A+  y+ a+
  EEA21522.1 927 LALSYYSYGLTLD---PKHAHLYTNLGSLWKDIGQLHAAIRMYELAV 970
                 5888899999999...*************999999999998777765 PP

  == domain 4  score: 12.1 bits;  conditional E-value: 0.00018
      TPR_16    2 alaraalragdyddAaaaleaalkrdpssPdaaeAllllgdaa 44  
                  +la+a  +ag+  dA+ ++++a+k +   Pd aeA  +l++a+
  EEA21522.1  982 NLANAVKDAGRINDAIVYYKRAVKVN---PDFAEAVCGLANAL 1021
                  6899999*******************...*******9999997 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0      0.57   7.2e+02      12      29 ..     568     583 ..     559     590 .. 0.75
   2 ?   -1.6   0.0       2.9   3.7e+03       1      19 [.     591     609 ..     591     620 .. 0.85
   3 ?   -0.2   0.1       1.1   1.4e+03       3      26 ..     730     753 ..     727     760 .. 0.81
   4 ?   -2.5   0.0       5.7   7.3e+03       1      11 [.     836     846 ..     836     846 .. 0.89
   5 !   10.4   0.1   0.00043      0.55       2      30 ..     946     972 ..     945     975 .. 0.88
   6 !    7.4   0.0    0.0038       4.8       1      32 [.     979    1008 ..     979    1012 .. 0.89

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.57
       TPR_7  12 lGdyeeAielyeqsLalt 29 
                 lGdy++A + y +   ++
  EEA21522.1 568 LGDYQKATRWYSR--IIA 583
                 8******999977..555 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 2.9
       TPR_7   1 aLlnLarlysrlGdyeeAi 19 
                 a++nLa ++ +l + eeA 
  EEA21522.1 591 AISNLAATFLALDQKEEAR 609
                 679********99999985 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 1.1
       TPR_7   3 lnLarlysrlGdyeeAielyeqsL 26 
                 ++ +++  +lGd + A+  +e+++
  EEA21522.1 730 HAKGNMLYALGDNAGAAAAFEEAI 753
                 567888899************954 PP

  == domain 4  score: -2.5 bits;  conditional E-value: 5.7
       TPR_7   1 aLlnLarlysr 11 
                 +Ll La +y++
  EEA21522.1 836 SLLSLAKIYQD 846
                 799******86 PP

  == domain 5  score: 10.4 bits;  conditional E-value: 0.00043
       TPR_7   2 LlnLarlysrlGdyeeAielyeqsLaltk 30 
                 + nL++l+ + G+   Ai+ ye   a+ +
  EEA21522.1 946 YTNLGSLWKDIGQLHAAIRMYEL--AVQY 972
                 78********************9..7655 PP

  == domain 6  score: 7.4 bits;  conditional E-value: 0.0038
       TPR_7    1 aLlnLarlysrlGdyeeAielyeqsLaltkdp 32  
                  aL nLa++  + G+  +Ai +y++  a+   p
  EEA21522.1  979 ALANLANAVKDAGRINDAIVYYKR--AVKVNP 1008
                  799*********************..887766 PP

>> TPR_9  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.4      0.16     2e+02       9      51 ..     569     611 ..     562     626 .. 0.82
   2 ?    1.2   0.2      0.31     4e+02      35      59 ..     732     756 ..     726     764 .. 0.84
   3 ?   11.0   0.1   0.00029      0.37      13      58 ..     927     972 ..     924     988 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.16
       TPR_9   9 edweralavverllllaPddpeerrdRGlllaqlGclsaAlad 51 
                  d+++a + + r+++ + +++e +   +     l++ ++A++ 
  EEA21522.1 569 GDYQKATRWYSRIIARDARHVEAISNLAATFLALDQKEEARQH 611
                 5889999999999999999999999999999999999999876 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.31
       TPR_9  35 RGlllaqlGclsaAladLeaylala 59 
                  G +l+ lG+ ++A+a++e ++ +a
  EEA21522.1 732 KGNMLYALGDNAGAAAAFEEAILIA 756
                 68899**************998665 PP

  == domain 3  score: 11.0 bits;  conditional E-value: 0.00029
       TPR_9  13 ralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylal 58 
                  al ++   l l+P++++++   G l    G+l+aA++  e +++ 
  EEA21522.1 927 LALSYYSYGLTLDPKHAHLYTNLGSLWKDIGQLHAAIRMYELAVQY 972
                 689999999****************************999888765 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.4   0.00064      0.82       8      78 ..     539     611 ..     534     615 .. 0.83
   2 ?   -0.6   0.1       1.2   1.6e+03       3      32 ..     991    1020 ..     957    1023 .. 0.74

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00064
                 HHHHHHHHH.HHH--HHHHHHHHHHH.HHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHH CS
      ANAPC3   8 AiflaerllaaetespedayllAlcl.ylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaa 78 
                 A+ +++ l++ +++   d +ll+ cl y +g+y++A +++++    + ++ ++   +A + l+L++ eeA+++
  EEA21522.1 539 ALEMLSHLCNESNWEWVDGMLLGGCLaYGLGDYQKATRWYSRIiARDARHVEAISNLAATFLALDQKEEARQH 611
                 566666666666666667778877765999****************************************987 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 1.2
                  T-HHHHHHHHHHHH.HHH--HHHHHHHHHH CS
      ANAPC3    3 nnyknAiflaerllaaetespedayllAlc 32  
                  +++++Ai ++ r+++ +++ +e++  lA +
  EEA21522.1  991 GRINDAIVYYKRAVKVNPDFAEAVCGLANA 1020
                  567778888888887777777777766665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1667 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       502  (0.0279993); expected 358.6 (0.02)
Passed bias filter:                      446  (0.0248759); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 1.01u 0.33s 00:00:01.34 Elapsed: 00:00:00.52
# Mc/sec: 9664.87
//
Query:       EEA21523.1  [L=584]
Description: endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   6.1e-178  592.4   0.0     7e-178  592.2   0.0    1.0  1  Glyco_hydro_47  Glycosyl hydrolase family 47


Domain annotation for each model (and alignments):
>> Glyco_hydro_47  Glycosyl hydrolase family 47
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  592.2   0.0  3.9e-182    7e-178       2     458 .]      99     582 ..      98     582 .. 0.98

  Alignments for each domain:
  == domain 1  score: 592.2 bits;  conditional E-value: 3.9e-182
                     HHHHHHHHHHHCTTSSEEETTTTEEE-SS.SS-CCHHHHHHHHHHCCHHHHHHHHHHHHHHC----S.SS.EEEHHHHHHHHHHHHHHHHHHH.S CS
  Glyco_hydro_47   2 fkhswegYkkyAwghDelrPlskkgrdtfgglgatlvDsLdtllimglkeefeeaveavekkidfdtsdskevsvFEttIRyLGGLlsaydlsek 96 
                     f h+w+gY+kyAw++De+ P+s++ r++fgg++atlvD+Ldtl+imgl++ef+eav av  k+df+t + +e++vFEttIRyLGG+l+ayd+s++
      EEA21523.1  99 FTHAWNGYRKYAWMSDEVAPISGEARNPFGGWAATLVDALDTLWIMGLYDEFDEAVLAVG-KLDFTTCSLEEINVFETTIRYLGGFLGAYDISQE 192
                     99**********************************************************.********************************** PP

                     -HHHHHHHHHHHHHHHHGGGSSTTS---SEEETTT--EE-.STCGCEEEHHHHCSSHHHHHHHHHHHT-CHHHHHHHCCHHHHHCHCC.HHHTTB CS
  Glyco_hydro_47  97 kedvllekAveladrLlpAFdtpsglpvarvnlkkrkaskkerassesvlAelgslslEftrLsqlTgdkkYedlaervtkaleelqektklpgl 191
                     k+++ll+kA+e++++L++AFdtp+++pv+r+++k++k++ +++a ++  +Ae+gsl+lEftrLsqlT+d++++d+++r+++++ e+q +tk+pgl
      EEA21523.1 193 KYPILLQKAIEIGEMLYKAFDTPNRMPVTRWKFKDAKGHLPQAAGEKVLAAEIGSLTLEFTRLSQLTKDARWFDAVQRIMDVFGEQQGQTKVPGL 287
                     *********************************99999999999888888*************************************9999**** PP

                     -BSEEETTT--EE.STEE-SSTTTHHHHHHHHHHHHHCTS--HHHHHHHHHHHHHHHHH.TEEE-TTT..--EEE-EECTT.....CTS.EE-EE CS
  Glyco_hydro_47 192 vpikidastgkfv.aekislgargDSyYEYllKqylllggeeeqyrkmyeealdaikkhllfrpskkkeddllfvgevtst.....eegklspei 280
                     +p +++a+t +f+  + +++g+++DS+YEYl+Kq++llgg+++qy+ +y  al+++k+h++frp++k+ +d+l+ g+v+        + +++p+ 
      EEA21523.1 288 WPVMVSAKTLNFHeFSGFTIGGMADSLYEYLPKQHVLLGGASHQYKILYLGALASMKHHIFFRPMTKDGQDVLLPGDVSWYdhdgvARPRIEPKA 382
                     *************7799************************************************************9654899887889***** PP

                     EGGGGHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHHHHTSTTS---SEEEE-SS.....S-ECTSSSSEEE-...................... CS
  Glyco_hydro_47 281 dhLscFlgGllalgakllekeedlelAkkltegcvkayeatktglmPEifevkpcesaeecewneekkdealk...................... 353
                     +hL cF+gG++algak ++ +edl++A+kl++gc++ ye+ + g+mPEi++  +ce++++c+w+e+k++ +++                      
      EEA21523.1 383 QHLGCFAGGMVALGAKVFGYPEDLSVARKLVDGCIWGYENAPLGIMPEIIHTVACEDQRDCPWDESKWYREVEntfsensaeetilsrrlapgvs 477
                     **********************************************************************999********************** PP

                     .GGG--B----HHHHHHHHHHHHH--THHHHHHHHHHHHHHHHCEETTEE--ECETTSSS-EE-S-B-HHHHHTHHHHHHHHC-S-TTT-TTTEE CS
  Glyco_hydro_47 354 riedrkyllRPEaiESlfylYritgdekyrevgwemfealekatktesgysaledVtkeepekeDemeSFwlaEtlKYlYLlFsdedvlsldeyV 448
                     +i d +y+lRPEaiES+f+lYritgd+ y e++w+mf+ + +++ t+ ++++l+d+t+ +p k+D+meSFwlaEtlKY+YL+Fs++dv+sldeyV
      EEA21523.1 478 KIDDGRYILRPEAIESIFILYRITGDPIYPEKAWTMFNHIIQHSITDIAHAGLNDCTVPNPPKQDRMESFWLAETLKYFYLMFSEPDVVSLDEYV 572
                     *********************************************************************************************** PP

                     E-TTS-EEE- CS
  Glyco_hydro_47 449 fnTeAHplkr 458
                     +nTeAHpl+r
      EEA21523.1 573 LNTEAHPLRR 582
                     ********96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (584 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       344  (0.0191868); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.30s 00:00:00.88 Elapsed: 00:00:00.48
# Mc/sec: 3676.73
//
Query:       EEA21524.1  [L=413]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.6e-07   29.0   0.1    1.8e-06   28.2   0.1    1.4  1  BTB       BTB/POZ domain
  ------ inclusion threshold ------
       0.21   11.8   1.4        0.7   10.1   0.0    2.2  2  ExbD      Biopolymer transport protein ExbD/TolR


Domain annotation for each model (and alignments):
>> BTB  BTB/POZ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.2   0.1     2e-10   1.8e-06      23     105 ..     142     234 ..     132     240 .. 0.85

  Alignments for each domain:
  == domain 1  score: 28.2 bits;  conditional E-value: 2e-10
                 EEE-HHHHHHH-HHHHHHHTST.......TTTTCCCEEEEETTSGHHHHHHHHHHHHHSEEEC-...CGGGHHHHHHHHHHHT-HHHHHHHHH CS
         BTB  23 fkahkavLaarSpyFkalftsk.......eieessvseielddvepeafealLefiYtgeleit...seenleelLaaadllqiprlkkacee 105
                 +++    L+ +Sp+Fk+l+t+        +  +++++ei+ + ++ +af +lL++i+++   i+   s e+l+++  +ad+++++++++  ++
  EEA21524.1 142 IQVSAKHLMLASPVFKSLLTGPwkesvtfSQLQKGSVEITAESCDVDAFLILLRIIHCQFNHIPrklSLEMLAKITVIADYYECKEVVRFFCD 234
                 55555668999***********9988887444555568*************************999*99*****************9987665 PP

>> ExbD  Biopolymer transport protein ExbD/TolR
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.3      0.12   1.1e+03      46      97 ..      43      94 ..      28      98 .. 0.60
   2 ?   10.1   0.0   7.8e-05       0.7      30      66 ..     112     150 ..     110     202 .. 0.75

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.12
        ExbD 46 tqkeveekelirisisadgsiyldkkavsveelaqklkerkakppdk.ltvai 97
                ++ +veek+ ++ +++  +  + d+   sv++ +++ k++k+ +++    v i
  EEA21524.1 43 EA-TVEEKDHVQSQVERADDAAEDGWGSSVKQSKKSKKNLKKAKNKSrSFVPI 94
                44.58999999999996655555554445555544444444443333234555 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 7.8e-05
        ExbD  30 lkkpeplevdlPsssstqk..eveekelirisisadgsi 66 
                 +++p  ++vd+P  +stqk  +++ +++++i++sa++ +
  EEA21524.1 112 VDVPVDVPVDVPVDESTQKtdQYQSENNVYIQVSAKHLM 150
                 56778899***********99*************99543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (413 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1157  (0.0645323); expected 358.6 (0.02)
Passed bias filter:                      748  (0.0417201); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.31s 00:00:00.96 Elapsed: 00:00:00.49
# Mc/sec: 2539.79
//
Query:       EEA21525.1  [L=238]
Description: glucose-methanol-choline (gmc) oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      1e-27   97.4   0.0    1.3e-27   97.0   0.0    1.1  1  GMC_oxred_C  GMC oxidoreductase


Domain annotation for each model (and alignments):
>> GMC_oxred_C  GMC oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.0   0.0   7.5e-32   1.3e-27       3     144 .]      71     209 ..      69     209 .. 0.88

  Alignments for each domain:
  == domain 1  score: 97.0 bits;  conditional E-value: 7.5e-32
                  --EEEEESTT-TCCEEEEE--TT-SHHHHHHHHHHHHHHHHHCTSGGG.TTEECCEECCCTTTTS.HCHHCHHCHHCHHHHH-EE-S--B-TT-B-ST CS
  GMC_oxred_C   3 srGrvtlsssdptgaplidpnylsdprdlaalvealkaarkilaaaal.dvleeeltpgaaeetsdaavesdealekfvkeavltsaHplGtcrMGad 99 
                  s+G+vtl+++++  +p i++n++ ++ d+ a++e+++++ ++l++ a  + l  + +p++         esd+ + ++v ++++t++H + t+r+ ++
   EEA21525.1  71 SEGQVTLNRTNALTQPNINLNFFGNDLDILAMREGVRWTYDVLTKGAGfKDLVISEYPWK------MPPESDDGMKRAVLDRSQTGFHLCATARLSKN 162
                  89*******************************************932222233333333......4678888999********************** PP

                  CGCBSB-TTSBBTT-CSEEE..-SGGGSSS--SS-THHHHHHHHHHH CS
  GMC_oxred_C 100 pkdsVVDsdlrvhgvdnLrV..vDaSvfPsapganptltilalAeka 144
                   +++VVD++lrvhg++nL++  +DaSv+  +p ++++ ++++++eka
   EEA21525.1 163 IQQGVVDPKLRVHGIKNLHIacADASVILVIPDCHIQNSVYMIGEKA 209
                  ******************96337**********************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (238 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       270  (0.0150594); expected 358.6 (0.02)
Passed bias filter:                      254  (0.014167); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.43
# Mc/sec: 1649.09
//
Query:       EEA21526.1  [L=165]
Description: 60S ribosomal protein L12 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.5e-24   84.4   0.2    5.6e-24   83.8   0.2    1.3  1  Ribosomal_L11_N  Ribosomal protein L11, N-terminal domain
      5e-14   52.6   0.1    8.8e-14   51.8   0.1    1.4  1  Ribosomal_L11    Ribosomal protein L11, RNA binding domain


Domain annotation for each model (and alignments):
>> Ribosomal_L11_N  Ribosomal protein L11, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.8   0.2   6.3e-28   5.6e-24       3      65 .]       5      69 ..       3      69 .. 0.95

  Alignments for each domain:
  == domain 1  score: 83.8 bits;  conditional E-value: 6.3e-28
  Ribosomal_L11_N  3 k...vvkvvklrvpaGkAtpaPplGpaLGplGlnikkfckefnkaTkdkkglripVkitvyqdrsf 65
                     +   +vkv++lr ++G++++ ++l+p++GplGl++kk++++++kaT+d+kglr++Vk+t+ q+r++
       EEA21526.1  5 FdpnEVKVIHLRATGGEVGAQSALAPKVGPLGLSPKKIGEDIAKATGDWKGLRVTVKLTI-QNRQA 69
                     55559*******************************************************.***96 PP

>> Ribosomal_L11  Ribosomal protein L11, RNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.8   0.1   9.9e-18   8.8e-14       2      70 .]      74     143 ..      73     143 .. 0.91

  Alignments for each domain:
  == domain 1  score: 51.8 bits;  conditional E-value: 9.9e-18
                    --SHHHHHHHHHTXSSXXSSTTTSXX..EEEEHHHHHHHHHHHGGGHTXS.SHHHHHHHHHHHHCTTTEEE CS
  Ribosomal_L11   2 tPptsylLkkaagiekgsgkpgketv..GtvslkqvyeIAkiKksdlnaalsleaavksilgtArsmGikV 70 
                    +P++s+l+++a++++++++k++k++    ++ l++++eIA++++  + a+ +l+++v +ilgtA s+G++V
     EEA21526.1  74 VPSASSLVIRALKEPPRDRKKEKNIKhsKSIPLDDIIEIARTMRARSLAK-ELRGTVLEILGTAFSVGCQV 143
                    7********************998446688**************555566.******************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (165 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       567  (0.0316247); expected 358.6 (0.02)
Passed bias filter:                      497  (0.0277205); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.44
# Mc/sec: 1123.32
//
Query:       EEA21527.1  [L=124]
Description: 60S ribosomal protein L12 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.9e-14   53.3   0.1    4.3e-14   52.8   0.1    1.3  1  Ribosomal_L11    Ribosomal protein L11, RNA binding domain
     0.0012   18.6   0.1     0.0023   17.7   0.1    1.4  1  Ribosomal_L11_N  Ribosomal protein L11, N-terminal domain


Domain annotation for each model (and alignments):
>> Ribosomal_L11  Ribosomal protein L11, RNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.8   0.1   4.8e-18   4.3e-14       2      70 .]      33     102 ..      32     102 .. 0.91

  Alignments for each domain:
  == domain 1  score: 52.8 bits;  conditional E-value: 4.8e-18
                    --SHHHHHHHHHTXSSXXSSTTTSXX..EEEEHHHHHHHHHHHGGGHTXS.SHHHHHHHHHHHHCTTTEEE CS
  Ribosomal_L11   2 tPptsylLkkaagiekgsgkpgketv..GtvslkqvyeIAkiKksdlnaalsleaavksilgtArsmGikV 70 
                    +P++s+l+++a++++++++k++k++    ++ l++++eIA++++  + a+ +l+++v +ilgtA s+G++V
     EEA21527.1  33 VPSASSLVIRALKEPPRDRKKEKNIKhsKSIPLDDIIEIARTMRARSLAK-ELRGTVLEILGTAFSVGCQV 102
                    7********************998446688**************555566.******************98 PP

>> Ribosomal_L11_N  Ribosomal protein L11, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.1   2.6e-07    0.0023      45      65 .]       9      28 ..       6      28 .. 0.90

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 2.6e-07
  Ribosomal_L11_N 45 TkdkkglripVkitvyqdrsf 65
                     T ++kglr++Vk+t+ q+r++
       EEA21527.1  9 TNKQKGLRVTVKLTI-QNRQA 28
                     889************.***96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (124 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       632  (0.0352502); expected 358.6 (0.02)
Passed bias filter:                      510  (0.0284455); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.44
# Mc/sec: 848.89
//
Query:       EEA21528.1  [L=393]
Description: transposon, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.9e-31  108.0   0.0    6.4e-31  107.4   0.0    1.3  1  DDE_1        DDE superfamily endonuclease
    5.3e-12   45.6   0.3    1.4e-11   44.2   0.1    2.0  2  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
    2.5e-06   27.1   0.0    4.7e-06   26.2   0.0    1.4  1  HTH_psq      helix-turn-helix, Psq domain
     0.0036   17.0   0.0      0.012   15.3   0.0    1.8  2  UPF0175      Uncharacterised protein family (UPF0175)
     0.0046   16.7   0.0      0.017   14.9   0.0    1.9  2  DDE_3        DDE superfamily endonuclease
  ------ inclusion threshold ------
      0.026   14.3   0.0       0.06   13.1   0.0    1.6  1  HTH_8        Bacterial regulatory protein, Fis family
      0.054   13.7   1.0          2    8.6   0.0    2.9  3  HTH_17       Helix-turn-helix domain


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  107.4   0.0   2.5e-34   6.4e-31       2     175 .]     204     373 ..     203     373 .. 0.93

  Alignments for each domain:
  == domain 1  score: 107.4 bits;  conditional E-value: 2.5e-34
       DDE_1   2 erltvllcanaagsekLkplvigka.ksprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrle..aekrkilLlldssrshetvel.les 95 
                 ++++++++a  +++  L++++i+ka k+ r  ++   ++ + d+++++++++w+t++i+ eWL  +f++ ++    +++ +L+l++++sh t+e+   +
  EEA21528.1 204 REWVTAIEATNSTGWALPSYIIFKAtKNVRVGWF---EDLPDDWRINISDNGWTTDQIGLEWLkTHFIPYINdrTRGKYRMLILNGHGSHLTAEFdRIC 299
                 7899********************8357899999...99999*****************************999999******************999* PP

       DDE_1  96 elqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                  ++ni  +++P++s++llqPld+g++  lK++Y +++ q + ++ n+ +k        d+l    +A++ a + +ti+++f
  EEA21528.1 300 TENNIIPIYMPPHSSHLLQPLDVGCFVVLKRYYGQHIEQRMRHGFNHVDK-------MDFLMAFPQARTvAYKAQTIRNSF 373
                 ***********************************************999.......788888888888888888888776 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.2   0.1   5.6e-15   1.4e-11       4      61 ..      72     125 ..      69     138 .. 0.90
   2 ?   -3.8   0.0       5.5   1.4e+04      27      36 ..     362     372 ..     359     378 .. 0.72

  Alignments for each domain:
  == domain 1  score: 44.2 bits;  conditional E-value: 5.6e-15
                  HHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT.S CS
  HTH_Tnp_Tc5   4 lEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh.g 61 
                  +E++L++W+ +l++rg p++++l+re+A++l+      +++d +++++W+++ +kR  +
   EEA21528.1  72 EEESLVKWVLDLDRRGLPPRHSLVREMANHLL-----SQHGDQQVGEKWVYNLIKRRpE 125
                  79*****************************6.....3469***************854 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 5.5
                  HHHHHHHHH.H CS
  HTH_Tnp_Tc5  27 irekAqela.s 36 
                  + +kAq ++ s
   EEA21528.1 362 VAYKAQTIRnS 372
                  67899999744 PP

>> HTH_psq  helix-turn-helix, Psq domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.2   0.0   1.8e-09   4.7e-06       2      40 ..      16      55 ..      15      59 .. 0.89

  Alignments for each domain:
  == domain 1  score: 26.2 bits;  conditional E-value: 1.8e-09
     HTH_psq  2 pealaaAleavvnGk.mSirkAArkYgiPrsTLwrrkrgk 40
                + ++ +A+ + +nGk   i++AA +Y+iPr+TL++r+ g+
  EEA21528.1 16 EGRILLAISDFQNGKiPNIAQAAEIYNIPRTTLRNRLHGT 55
                567899*********889****************999886 PP

>> UPF0175  Uncharacterised protein family (UPF0175)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   4.6e-06     0.012      10      55 ..       7      53 ..       4      57 .. 0.90
   2 ?   -2.8   0.0         2   5.2e+03      49      69 ..      78      98 ..      75     100 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 4.6e-06
     UPF0175 10 klteeelerelrialAvklYeegrlS.lgkAaelaglsrveflelLa 55
                k++++ +e+e ri+lA++ ++ g++  +++Aae+ +++r + ++ L+
  EEA21528.1  7 KKSKDLIEQEGRILLAISDFQNGKIPnIAQAAEIYNIPRTTLRNRLH 53
                5688899******************858***********99998885 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 2
     UPF0175 49 eflelLarrgiplinydeeel 69
                 +   L rrg p+++  + e+
  EEA21528.1 78 KWVLDLDRRGLPPRHSLVREM 98
                566779999999998766665 PP

>> DDE_3  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       1.4   3.5e+03       6      48 ..     172     217 ..     168     233 .. 0.67
   2 !   14.9   0.0   6.7e-06     0.017      66     119 ..     266     316 ..     255     322 .. 0.92

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 1.4
       DDE_3   6 DEsgfqlgt.vrrrawakkGkrer..leeygrrgrvnligaldekg 48 
                 D +gf  g    ++   + ++ +r  l + ++r+ v++i a++  g
  EEA21528.1 172 DKTGFAMGLcATAKVITRSDRYARpkLLQPRNREWVTAIEATNSTG 217
                 6666666666666666666666333377777778888888777655 PP

  == domain 2  score: 14.9 bits;  conditional E-value: 6.7e-06
       DDE_3  66 eflerlletalqakkivlilDnasiHkseslrelveeeadrlellylPpySPel 119
                 +f+ +++++ + +   +lil +++ H  +++ ++  e   ++  +y+Pp+S++l
  EEA21528.1 266 HFIPYINDRTRGK-YRMLILNGHGSHLTAEFDRICTE--NNIIPIYMPPHSSHL 316
                 5778888888886.9**********************..*************98 PP

>> HTH_8  Bacterial regulatory protein, Fis family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   2.3e-05      0.06      20      39 ..      33      52 ..      33      53 .. 0.97

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2.3e-05
                -HHHHHHHHTS-HHHHHHHH CS
       HTH_8 20 nkskAArlLGisRrtLyrKL 39
                n+++AA++ +i R+tL+++L
  EEA21528.1 33 NIAQAAEIYNIPRTTLRNRL 52
                99*****************8 PP

>> HTH_17  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.0    0.0008         2       4      20 ..      34      50 ..      33      58 .. 0.91
   2 ?    2.3   0.1     0.074   1.9e+02      13      27 ..     111     126 ..     110     138 .. 0.75
   3 ?   -2.5   0.0       2.3     6e+03      20      37 ..     261     280 ..     261     281 .. 0.68

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0008
      HTH_17  4 veEaAelLgvsrstvyr 20
                +++aAe+ ++ r+t+++
  EEA21528.1 34 IAQAAEIYNIPRTTLRN 50
                89*************97 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.074
      HTH_17  13 vsrstvyrlirrg.el 27 
                 v+++ vy+li+r  e+
  EEA21528.1 111 VGEKWVYNLIKRRpEI 126
                 78999*****998455 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 2.3
      HTH_17  20 rlirrgelpaa..k.iGrrwr 37 
                 ++++++ +p+   + +G+ +r
  EEA21528.1 261 EWLKTHFIPYIndRtRGK-YR 280
                 588999997776645654.76 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (393 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       425  (0.0237046); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.53u 0.24s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 2784.38
//
Query:       EEA21529.1  [L=772]
Description: protein transport protein Sec23, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.6e-80  270.2   0.0    2.4e-80  269.6   0.0    1.3  1  Sec23_trunk     Sec23/Sec24 trunk domain
    4.4e-29  101.1   0.0    9.8e-29  100.0   0.0    1.6  1  Sec23_BS        Sec23/Sec24 beta-sandwich domain
    3.6e-24   84.5   0.0    8.2e-24   83.4   0.0    1.6  1  Sec23_helical   Sec23/Sec24 helical domain
    2.5e-14   53.0   4.1    4.5e-14   52.2   4.1    1.5  1  zf-Sec23_Sec24  Sec23/Sec24 zinc finger
      8e-12   44.9   0.0    3.8e-11   42.7   0.0    2.1  2  Gelsolin        Gelsolin repeat
  ------ inclusion threshold ------
      0.019   14.3   1.3      0.029   13.8   0.3    1.8  2  Vps36-NZF-N     Vacuolar protein sorting 36 NZF-N zinc-finger


Domain annotation for each model (and alignments):
>> Sec23_trunk  Sec23/Sec24 trunk domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  269.6   0.0   8.2e-84   2.4e-80       1     243 []     127     395 ..     127     395 .. 0.98

  Alignments for each domain:
  == domain 1  score: 269.6 bits;  conditional E-value: 8.2e-84
                  SS--EEEEEEE-SHHHHHHTHHHHHHHHHHHHCTTSSTSTT-EEEEEEESSSEEEEETSTTS.......SSSEEEEECHTTSCC.............. CS
  Sec23_trunk   1 pkppvflFviDvsleaikegelkalkeslkqsLdllPeepralvglitfdsvvhffelksel.......rqpkelvvsdlqdvf.............. 77 
                  p pp+f++v+D+++e   ++ l+alk+sl++sL+llP  p+alvglit++++ +++el++ +       r++k+++++++q+++              
   EEA21529.1 127 PAPPIFVYVVDTCQE---DDGLQALKDSLIMSLSLLP--PNALVGLITYGTMAQVHELGYGEcaksyvfRGSKDYTAKQVQEMLgllnagvrpgapqq 219
                  78*************...*******************..*********************************************************** PP

                  ........SSTSSSSSEETTTTHHHHHHHHHHHHH.HSTT-TTC-----HHHHHHHHHHHHCHCT..S-EEEEEEESS---SSTTTSS-SBTTS...C CS
  Sec23_trunk  78 ........lpladrlLvplseseavledlLeelpe.mfavtagkrperalgpalkaavellkave..tggkiivfvgslptvgaggklksrede...s 161
                          +  a r+L+p++++e++++++Le+l++ +++v+++kr  r++g+a+++av+ll++++  +gg+i+vf+++++t g+g ++  +++e   s
   EEA21529.1 220 pgrmppppMGPAARFLLPVQQAEFQITNILEQLQRdPWPVANDKRALRCTGVAVSVAVGLLETSFqnAGGRIMVFASGPATEGPGIVVGPELKEpirS 317
                  *****9776677**************************************************99999**************************99*** PP

                  CTSSTTCHHCHSCSSSCHHHHHHHHHHHCTEEEEEEEECSS--SHHHHTHHHHTTT-EEEEETTTCCHHHHHHHHHHHHHHH CS
  Sec23_trunk 162 lldidkekaklvkkadkfYkkLakecvkqgisvDlFlfsldyvdlaelkqlaeltgGqvvlydsFsaekdasklkqdlkrvv 243
                  ++did+++ k++kka kfY++Lak+++++g+++DlF+++ld+v+++e+k++a+ tgG+++l+dsF+    +s++kq++ rv+
   EEA21529.1 318 HHDIDRDNVKYFKKAVKFYDSLAKRAAHNGHVIDLFAGCLDQVGMLEMKNMANHTGGHILLTDSFT----SSQFKQSFVRVF 395
                  ******************************************************************....*********986 PP

>> Sec23_BS  Sec23/Sec24 beta-sandwich domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.0   0.0   3.3e-32   9.8e-29       1      95 [.     406     510 ..     406     511 .. 0.92

  Alignments for each domain:
  == domain 1  score: 100.0 bits;  conditional E-value: 3.3e-32
                 EEEEEEEEEE-TTEEEEEEESSSEEC....STBESSEESECSESEEEEEEEETT--EEEEEEE.....SSBTCTT.SEEEEEEEEEEEETTSEEEEEEE CS
    Sec23_BS   1 gfnatlevrtSkelkvsgliGncvsl....snvsekeiGeggtsewklcsldpdstlavyfdi.....deklksg.kqayiQfatlYthssgerrlRVt 89 
                 gfna+lev t+kelkv+gliG+++sl    s+v e+e+G+g+t++wk+c +dp  ++++yf+i      +++++g ++ ++Qf+t Y+hssg+ +lRVt
  EEA21529.1 406 GFNASLEVLTTKELKVTGLIGHAISLnkksSSVGETECGIGNTCAWKMCGIDPAASYGIYFEIanqggPAPMQQGpQRGMMQFLTYYQHSSGQFHLRVT 504
                 79************************8887689999***************************9999944555554999******************** PP

                 EEEEEE CS
    Sec23_BS  90 tvalpv 95 
                 t+a+++
  EEA21529.1 505 TIARNL 510
                 **9986 PP

>> Sec23_helical  Sec23/Sec24 helical domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.4   0.0   2.8e-27   8.2e-24       1     102 [.     524     622 ..     524     623 .. 0.97

  Alignments for each domain:
  == domain 1  score: 83.4 bits;  conditional E-value: 2.8e-27
                    -HHHHHHHHHHHHHHHTTTS-HHHHHHHHHHHHHHHHHHHHHH-------------GGGTTHHHHHHHHHTSTTTS-.-TT--HHHHHHHHHHHHH CS
  Sec23_helical   1 DqeavtvllakqaidkalesgladarealdtslvdllsayrkvgasgsspsqlqlpeslklLPlyilallKspafrg.gnsvpaDervfalsllls 95 
                    Dqea++vl+++ a+ ka+  +  d+ +++d+ l++l+s++ ++ ++  +p +++l +++ l+P+++++l++s+ f++ +n++p De++f+++ l++
     EEA21529.1 524 DQEAAAVLMSRIAVFKAEVDDGPDVLRWVDRMLIRLCSRFADYRKD--DPTSFRLEKNFTLYPQFMFHLRRSQ-FLQvFNNSP-DETAFYRHVLNH 615
                    9*****************99************************99..9************************.8888*****.************ PP

                    --HHHHH CS
  Sec23_helical  96 lpvdqll 102
                    +++ ++l
     EEA21529.1 616 EDTGNSL 622
                    **99887 PP

>> zf-Sec23_Sec24  Sec23/Sec24 zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.2   4.1   1.5e-17   4.5e-14       1      39 []      60      99 ..      60      99 .. 0.99

  Alignments for each domain:
  == domain 1  score: 52.2 bits;  conditional E-value: 1.5e-17
  zf-Sec23_Sec24  1 PirCrr.CraylNpfckidfggkrwiCnfCnhknevppeY 39
                    P+ C+  C+a+lNp++++d +++ wiC+fC  +n++pp+Y
      EEA21529.1 60 PVTCKApCKAVLNPYANVDIRARIWICPFCLMRNPLPPHY 99
                    99*************************************9 PP

>> Gelsolin  Gelsolin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0      0.71   2.1e+03      28      49 ..     186     210 ..     167     227 .. 0.79
   2 !   42.7   0.0   1.3e-14   3.8e-11       5      76 .]     639     725 ..     635     725 .. 0.96

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.71
                 EEEEEEHTT...SHHHHHHHHHHHH CS
    Gelsolin  28 tiflWiGke...ssqeeknfaadla 49 
                 + ++++G++   + q +++++ ++a
  EEA21529.1 186 KSYVFRGSKdytAKQVQEMLGLLNA 210
                 67999***99999999999999887 PP

  == domain 2  score: 42.7 bits;  conditional E-value: 1.3e-14
                 EEEBSSSGGGEETTSEEEEEESS........EEEEEEHTT..SHHHHHHHHHHHHHHHH.....HCTTTTTSEEEEEETTHHHHHHH CS
    Gelsolin   5 pkvvklsssslesgdcyLLdngf........tiflWiGke..ssqeeknfaadlaaeld.....seerfplpeliredqgkeparFl 76 
                  ++v+l+s s+++  ++LLd++f        t++ W++++  +++ ++nf+a l+++ +       +rfplp++i +d g+++arFl
  EEA21529.1 639 SQPVLLDSASIQPTHILLLDTFFhllifhgeTMAEWRKAGyqDQEGYENFKAILEQPKEdarelIADRFPLPRFIICDAGGSQARFL 725
                 689**************************************9999*******************9999******************7 PP

>> Vps36-NZF-N  Vacuolar protein sorting 36 NZF-N zinc-finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.3   9.7e-06     0.029       9      34 ..      83     108 ..      76     110 .. 0.81
   2 ?   -3.5   0.0       2.4   7.2e+03      38      44 ..     453     459 ..     452     461 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 9.7e-06
  Vps36-NZF-N   9 tWvCpICsfsNevpsnfdpnastplP 34 
                   W+Cp C + N++p  ++   ++ +P
   EEA21529.1  83 IWICPFCLMRNPLPPHYKDITENAIP 108
                  6*************999975555565 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 2.4
  Vps36-NZF-N  38 aCGvkpd 44 
                  +CG+ p 
   EEA21529.1 453 MCGIDPA 459
                  7***985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (772 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       446  (0.0248759); expected 358.6 (0.02)
Passed bias filter:                      427  (0.0238162); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.65u 0.27s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 5164.84
//
Query:       EEA21530.1  [L=501]
Description: DNA primase large subunit [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.5e-87  291.3   0.0    9.8e-87  290.7   0.0    1.3  1  DNA_primase_lrg  Eukaryotic and archaeal DNA primase, large s


Domain annotation for each model (and alignments):
>> DNA_primase_lrg  Eukaryotic and archaeal DNA primase, large subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  290.7   0.0   5.5e-91   9.8e-87       2     266 .]     199     484 ..     198     484 .. 0.98

  Alignments for each domain:
  == domain 1  score: 290.7 bits;  conditional E-value: 5.5e-91
                      EEEEEHHHHHHHTT-GGS-EETTEEEE-HHHHHHHHHHHHHHHHHH..........HHGGGSSS---HHHHHHHCT--................ CS
  DNA_primase_lrg   2 fykvpfedvldlvkrrrvllkkGyaylpkeeleslllekfrkrlekalestkeslpeleeeikederekleellealsesyvaed......vqe 89 
                      ++kv++e+v++l++rr v+++kG+ay+p++e++s++++ f++rleka+e t+++lp+l    +ed+r  l+++l++ls+++ +++      ++ 
       EEA21530.1 199 WFKVDWEKVPELIERRVVFIRKGKAYVPQREQLSMIIADFTARLEKAMELTSRALPRL----DEDDR--LTPILNHLSKNFGSAEsvysegEGV 286
                      79********************************************************....*****..*********99999999*9999999 PP

                      ...TTSSTTGGSHHHHTT--HHHHCCHHHHCCCSS--CHHHHHHHHHHHHCT--CHHHHCCCHCHST...HHHHHHHTHCHCHHHCC-STT--- CS
  DNA_primase_lrg  90 eedskisaknidklakesfPpCmrelleglkknghlkhegrlqltlFlkdiglsldeilelwkeaftr.teekFdkeyrynirhnyGkegkrtn 182
                       +++ i+a +id l+ ++fP+Cmr+l+++l+kn+hlkh grlq+tlFlk+iglslde++ +w+++f+  ++++F+++y+ynirh yG++g+++n
       EEA21530.1 287 VDGAPITAASIDPLS-QHFPLCMRSLHMTLRKNNHLKHFGRLQYTLFLKGIGLSLDECILFWRQSFKGfSDDEFNSKYKYNIRHSYGDVGGDAN 379
                      99************9.9***************************************************************************** PP

                      .....-----HHHHHHS....TT---S-HHHH..HHHHHHHHHHTT...HHHHHHHHHHHHTT.HHHHHHHHHHHHHS..............-T CS
  DNA_primase_lrg 183 .....yspysCekiltkpppgkgdahgCpfrh.dpdklktlLqeyg.lseediedilesvkegeyqvaCtkvFelthk..............ce 255
                           y+pysC++il+++ p++g++hgCp+rh + d+l++lLq++g  +++ ++ ++e+v +++y++aC++vFe+thk              ++
       EEA21530.1 380 rrgrgYPPYSCQRILSESAPSTGQTHGCPYRHfSVDNLTALLQSTGvHDKDLLRGVREDVGKQKYHIACNRVFEWTHKadikrvkedgswsqTD 473
                      **********************************************9999999**************************************999 PP

                      TT-SSCHHHCC CS
  DNA_primase_lrg 256 rdeikhPlqYy 266
                       d+i hP++Y+
       EEA21530.1 474 LDTIVHPNTYF 484
                      99********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (501 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       521  (0.0290591); expected 358.6 (0.02)
Passed bias filter:                      449  (0.0250432); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.43
# Mc/sec: 3464.68
//
Query:       EEA21531.1  [L=250]
Description: adenylate kinase 2 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.2e-36  124.7   0.0    5.5e-19   68.7   0.0    2.1  2  ADK       Adenylate kinase
    1.8e-16   59.8   0.1    1.4e-15   56.9   0.0    2.1  2  ADK_lid   Adenylate kinase, active site lid
    4.4e-14   53.1   0.0    1.2e-11   45.2   0.0    2.5  2  AAA_17    AAA domain
    6.5e-06   26.7   0.0    2.3e-05   25.0   0.0    1.9  1  AAA_18    AAA domain
      0.004   17.3   0.2      0.045   13.9   0.0    2.5  2  AAA_33    AAA domain
  ------ inclusion threshold ------
      0.023   14.9   0.0      0.039   14.2   0.0    1.4  1  AAA_28    AAA domain
      0.066   12.2   0.1      0.094   11.7   0.1    1.2  1  MeaB      Methylmalonyl Co-A mutase-associated GTPase MeaB
      0.094   13.0   0.0       0.17   12.1   0.0    1.4  1  AAA_22    AAA domain
        0.1   12.6   0.1       0.19   11.7   0.1    1.4  1  AAA_5     AAA domain (dynein-related subfamily)


Domain annotation for each model (and alignments):
>> ADK  Adenylate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.7   0.0   2.8e-22   5.5e-19       1      71 [.      16      87 ..      16     107 .. 0.93
   2 !   54.2   0.0   8.6e-18   1.7e-14      75     150 ..     118     224 ..     107     225 .. 0.96

  Alignments for each domain:
  == domain 1  score: 68.7 bits;  conditional E-value: 2.8e-22
                EEESTTSSHHHHHHHHHHHH.TSEEEEHHHHHHHHHHCT-HHHHHHHHHHHTTSS--HHHHHHHHHHHHHCH CS
                xxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         ADK  1 llGaPgaGKGtqaeklvkky.glahlstGdllRaevksgtelGkeakevmdkgelvpdevvvklvkeeleke 71
                l+GaPg GKGtq+e+l  ++ +la +s+GdllR++v+++t lG +a++++++g+lvpd v+++l+++el ++
  EEA21531.1 16 LIGAPGVGKGTQTERLLARFpQLAAISSGDLLRENVRKKTALGLQAEALIQAGKLVPDAVMLDLISSELVTK 87
                79***************9996799*******************************************99865 PP

  == domain 2  score: 54.2 bits;  conditional E-value: 8.6e-18
                 TEEEEESB-SSHHHHHHHHHHHHHHTSEESEEEEEE--HHHHHHHHHT....................................GSHHHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....................................xxxxxxxxxxxxxxx RF
         ADK  75 kgfllDGfPRtveqaealeelleeekvkldlvleldvpeevlveRltg....................................DneetvkkRletykk 137
                   f+lDGfPRt  qa++l++     +  +++v++l  p +v+++R+t+                                    D+ +t k+Rl+++++
  EEA21531.1 118 ASFILDGFPRTAVQANSLDR-----ILPINFVVHLFTPPSVIISRITKrwvhapsgrvyntdfnppkvegkddvtgesltqradDSIDTWKQRLRKFEE 211
                 68******************.....669*********************************************************************** PP

                 HHHHHHHHHHHTT CS
                 xxxxxxxxxxxxx RF
         ADK 138 qtkplidyykkkg 150
                 ++k li++y+++g
  EEA21531.1 212 SSKTLIEHYERQG 224
                 *********9986 PP

>> ADK_lid  Adenylate kinase, active site lid
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.1      0.37   7.4e+02       7      18 ..     101     112 ..      99     116 .. 0.71
   2 !   56.9   0.0   7.1e-19   1.4e-15       1      36 []     161     196 ..     161     196 .. 0.99

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.37
                 T--EEETTT.B-- CS
     ADK_lid   7 CGrsYhvvf.npP 18 
                 +  sY+ +  +pP
  EEA21531.1 101 SSSSYN-QHnKPP 112
                 7789**.553777 PP

  == domain 2  score: 56.9 bits;  conditional E-value: 7.1e-19
                 EEE-TTT--EEETTTB--SSTTB-TTT--.-B--GG CS
     ADK_lid   1 RrvCpkCGrsYhvvfnpPkveglCDkCGepLvqRsD 36 
                 R+v+  +Gr+Y+  fnpPkveg++D++Ge L+qR+D
  EEA21531.1 161 RWVHAPSGRVYNTDFNPPKVEGKDDVTGESLTQRAD 196
                 9***********999********************9 PP

>> AAA_17  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.2   0.0     6e-15   1.2e-11       1     127 [.      17     169 ..      17     174 .. 0.79
   2 ?   -3.0   0.0       4.6   9.2e+03     126     136 .]     193     203 ..     187     222 .. 0.71

  Alignments for each domain:
  == domain 1  score: 45.2 bits;  conditional E-value: 6e-15
                 EE-TTSSHHHHHHHHHHHH.TEEEEEHHHHHHHHHHTTTS..HSSHHHHCTSHHHHHHHHHHHHHHHH......................HHHH..... CS
      AAA_17   1 lGgPGsGKgtqceklveky.gfthlsaGdllreeakrggl..akardemrklpleekkelqkeaaeki......................aeea..... 69 
                 +G PG+GKgtq e+l  ++ ++  +s Gdllre+++++ +   +a+  ++ ++l+++  +++++  ++                      ++ +     
  EEA21531.1  17 IGAPGVGKGTQTERLLARFpQLAAISSGDLLRENVRKKTAlgLQAEALIQAGKLVPDAVMLDLISSELvtkgwlkpsepfatqqssssynQH-Nkppsi 114
                 69*************999989**************999533346777788999999999999999998888888888888876655555422.134455 PP

                 .HSSEEEEEE-SEEEETTEEEESSHHHHHHHH..SEEEEEE--HHHHHHHHHHH...TTST- CS
      AAA_17  70 .kkkgvlvdghprikeqagfldglpkevleelkpdaiilleadpeeilerrlkd...rtrgr 127
                   +  +++dg+pr+  qa  ld       + l +++++ l ++p +i++r  k+     +gr
  EEA21531.1 115 aPSASFILDGFPRTAVQANSLD-------RILPINFVVHLFTPPSVIISRITKRwvhAPSGR 169
                 455669******9988888655.......57888*****************99954223666 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 4.6
                 T-TS-SHHHHH CS
      AAA_17 126 grdddneesik 136
                 +r+dd+++++k
  EEA21531.1 193 QRADDSIDTWK 203
                 46666666654 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.0   0.0   1.1e-08   2.3e-05       1     114 [.      14     162 ..      14     176 .. 0.78

  Alignments for each domain:
  == domain 1  score: 25.0 bits;  conditional E-value: 1.1e-08
      AAA_18   1 IlltGtpGvGKttlakeLskrl.gf.....gvnlrdvakenglllevdpe.........................aldeskrldedkldklldaleens 68 
                 I+l G+pGvGK t +++L  r  ++     g+ lr++++++  l  + ++                         +l++s+ + +++  +  +++++ +
  EEA21531.1  14 IILIGAPGVGKGTQTERLLARFpQLaaissGDLLRENVRKKTALGLQAEAliqagklvpdavmldlisselvtkgWLKPSEPFATQQSSSSYNQHNKPP 112
                 9*****************888655588888666666666666555555555555555555555555555577779999999999999666666666655 PP

      AAA_18  69 saleegknlvidghlaeleseaakdikk.....vvLtaspeelleRlekRg 114
                 s  +   + ++dg++   ++++  d+       v+L ++p++ + R+ kR 
  EEA21531.1 113 S-IAPSASFILDGFPRTAVQANSLDRILpinfvVHLFTPPSVIISRITKRW 162
                 5.8899999**************999999********************95 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   0.0   2.2e-05     0.045       2      39 ..      14      53 ..      14     179 .. 0.72
   2 ?   -2.2   0.0       2.1   4.2e+03     109     117 ..     200     208 ..     183     223 .. 0.60

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 2.2e-05
      AAA_33  2 vllvGlpGsGKstlaerllkklg..avllssdtlrrrlfg 39
                ++l+G+pG+GK t  erll++ +  a + s d lr+++++
  EEA21531.1 14 IILIGAPGVGKGTQTERLLARFPqlAAISSGDLLRENVRK 53
                699****************999996443344444445554 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 2.1
      AAA_33 109 etlkeRlak 117
                 +t+k+Rl+k
  EEA21531.1 200 DTWKQRLRK 208
                 344444443 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0     2e-05     0.039       1      43 [.      13      55 ..      13      78 .. 0.72

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 2e-05
      AAA_28  1 kivitGgestGKTtlleaLaargypvvpEaareileeklakge 43
                +i+++G+++ GK t +e+L ar  +  + +  ++l+e+ +k++
  EEA21531.1 13 RIILIGAPGVGKGTQTERLLARFPQLAAISSGDLLRENVRKKT 55
                79*******************9666555555555555554433 PP

>> MeaB  Methylmalonyl Co-A mutase-associated GTPase MeaB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.1   4.7e-05     0.094      20      53 ..       2      35 ..       1      40 [. 0.86

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 4.7e-05
                HHHGGG-S-SEEEEEEE-TTSSHHHHHHHHHHHH CS
        MeaB 20 erllakaGraqvvGltGvPGaGkstlvealglel 53
                + ++++  +a ++ l G PG+Gk t +e+l +++
  EEA21531.1  2 TSVTKRLKKAARIILIGAPGVGKGTQTERLLARF 35
                5667778899*******************98876 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   8.7e-05      0.17       5      35 ..      11      41 ..       6      67 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 8.7e-05
      AAA_22  5 agilvvtGesGtGKTtllrrlleqldeeaka 35
                a  ++++G +G+GK t  +rll ++++ a++
  EEA21531.1 11 AARIILIGAPGVGKGTQTERLLARFPQLAAI 41
                56689*******************9986655 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.1   9.6e-05      0.19       2      24 ..      14      36 ..      13      44 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 9.6e-05
                EEEE--SSSSHHHHHHHGGGGBS CS
       AAA_5  2 vlLvGppGtgKselaerlaaaln 24
                ++L+G+pG+gK + +erl+a++ 
  EEA21531.1 14 IILIGAPGVGKGTQTERLLARFP 36
                79****************99985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (250 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       566  (0.031569); expected 358.6 (0.02)
Passed bias filter:                      526  (0.0293379); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 1748.85
//
Query:       EEA21532.1  [L=344]
Description: nuclease domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-21   77.4   0.0    1.7e-21   76.7   0.0    1.3  1  SNase     Staphylococcal nuclease homologue


Domain annotation for each model (and alignments):
>> SNase  Staphylococcal nuclease homologue
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.7   0.0   9.6e-26   1.7e-21       2     108 .]     165     282 ..     164     282 .. 0.92

  Alignments for each domain:
  == domain 1  score: 76.7 bits;  conditional E-value: 9.6e-26
                 EEETTEE-STSSBTTTTTSTTHHHHHHHHHHHHHHCSSEEEEE-SSBSTTSEEEEEEEET.........TEEHHHHHHHTTSSEE---BTT....STTT CS
       SNase   2 vrLvgidaPetakpkktvqpfgkeAkeflkklvlqkkvvvleldkkkDkygrllayvyln.........kknineeLvkeGlArvyevyek....neek 87 
                 +rL+g+daPe a++++++qp+++eA+ +l + ++++ v+  +     D+y r++a+vy+          +++++ e+++ GlA+vye+ +      +e+
  EEA21532.1 165 IRLAGVDAPELAHFGRPAQPYAYEAHMWLTSYLMNRRVRAYVHRP--DQYKRVIATVYVRrwldfpplrRRDVSYEMLRRGLATVYEAKSGvefgGTEN 261
                 9*********************************88888888877..****************************************655445455689 PP

                 HHHHHHHHHHHHHTT-GGGCT CS
       SNase  88 kkellkaeeeAkkkrkglWse 108
                 + ++++ae  Ak++r glW++
  EEA21532.1 262 ERKYREAEMLAKNRRQGLWKD 282
                 99*****************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (344 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       657  (0.0366445); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.48
# Mc/sec: 2168.06
//
Query:       EEA21533.1  [L=336]
Description: peroxisomal carrier protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.1e-55  185.5   0.3    5.8e-19   67.8   0.0    3.1  3  Mito_carr  Mitochondrial carrier protein


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.8   0.0   3.2e-23   5.8e-19       3      93 ..       7     107 ..       5     110 .. 0.95
   2 !   55.5   0.0   2.3e-19   4.2e-15       4      94 ..     118     204 ..     115     207 .. 0.93
   3 !   59.1   0.0   1.7e-20     3e-16       3      93 ..     210     301 ..     208     303 .. 0.90

  Alignments for each domain:
  == domain 1  score: 67.8 bits;  conditional E-value: 3.2e-23
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSS..........HHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   3 lsvlkellaGglagavatlvttPldvvKtrlqtqkksskksksaa..........ildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkr 91 
                 l ++++ +aG++++++a  +++Pld+vKt++q+q ks k+++s+           +ld++ ki+++eGl gly G++ +l++va++++++f  y +++ 
  EEA21533.1   7 LAPWESAIAGATGAVLANALVYPLDIVKTKIQVQVKSRKETTSNTnpdatphyesTLDAINKIFQDEGLPGLYNGINGALIGVASTNFAYFYWYSVVRA 105
                 6789*********************************9999998899************************************************9987 PP

                 HH CS
   Mito_carr  92 ll 93 
                  +
  EEA21533.1 106 AY 107
                 66 PP

  == domain 2  score: 55.5 bits;  conditional E-value: 2.3e-19
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHH.HHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
   Mito_carr   4 svlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiyk.eeGlrglyrGllpnllrvapasalkfvlyetlkrlll 94 
                 +++ el  G++aga+a+++t P+ vv tr qtq+k+ kk     +l++ ++++  e+G +gl+rGl ++l+ v+ + a++ ++y+ lk++l+
  EEA21533.1 118 GTAVELSLGAIAGAIAQIFTIPVSVVTTRQQTQSKEDKKG----LLETAREVIDgEDGWTGLWRGLKASLVLVV-NPAITYGAYQRLKEILF 204
                 677899******************************9883....9********889****************99.*************9986 PP

  == domain 3  score: 59.1 bits;  conditional E-value: 1.7e-20
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTS.CSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   3 lsvlkellaGglagavatlvttPldvvKtrlqtqkksskksk.saaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrll 93 
                 l++++ ++ G++++a+at+vt+Pl v+K+ lq+ +  +++ k ++++++v++ i+++eG ++l++G++p++++    ++l +++ e +  l+
  EEA21533.1 210 LRPWEAFILGAMSKALATMVTQPLIVAKVGLQSRPPPGRQGKpFKGFIEVMQYIIEHEGPLSLFKGIGPQITKGLLVQGLLMMTKERMELLF 301
                 6899*****************************9998765441455****************************************998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (336 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       800  (0.0446204); expected 358.6 (0.02)
Passed bias filter:                      622  (0.0346924); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.24s 00:00:00.76 Elapsed: 00:00:00.40
# Mc/sec: 2495.25
//
Query:       EEA21534.1  [L=289]
Description: endo-1,4-beta-xylanase 1 precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.9e-65  219.8  14.8    1.9e-65  219.8  14.8    1.6  2  Glyco_hydro_11  Glycosyl hydrolases family 11
    2.2e-13   49.9  12.6    2.2e-13   49.9  12.6    2.2  2  CBM_1           Fungal cellulose binding domain


Domain annotation for each model (and alignments):
>> Glyco_hydro_11  Glycosyl hydrolases family 11
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  219.8  14.8   2.2e-69   1.9e-65       4     177 ..      56     226 ..      52     227 .. 0.95
   2 ?   -3.2   0.7      0.64   5.7e+03      32      55 ..     260     279 ..     243     284 .. 0.72

  Alignments for each domain:
  == domain 1  score: 219.8 bits;  conditional E-value: 2.2e-69
                     -EEEEEECCCSEEEEEC-TTTEEEEEEECSSEEEEEEEESS-TT-EEEEEEEEEECC.EEEEEEEEEECTTTEEEEEEEEESSS-HHHHSEEEEE CS
  Glyco_hydro_11   4 yyyslwkdgggsvtytngaggsysvswsnagnfvvgkGwnpgskrtikYsgtyspsg.nsylavYGWtrnplvEYYivenwgsynpssgatkkgt 97 
                     +y + +++g gsv+y+  ++  +sv+wsna++fvvg Gw++g+++ i++ g++s sg +++l+vYGWt+nplvEYY++e++   np +++t kgt
      EEA21534.1  56 NYNQDYTTG-GSVNYSP-SSTGFSVNWSNANDFVVGVGWQTGTTSPITFGGSFSVSGgTGLLTVYGWTTNPLVEYYVMEDY--SNPPTQGTIKGT 146
                     578889999.*****99.5556********************************8777***********************..57889******* PP

                     EEETTEEEEEEEEEEEEEEETTEEEEEEEEEEEESS--SCEEEEHHHHHHHHHHCT---SEECEEEEEEEEEEEEEEEEE CS
  Glyco_hydro_11  98 vtsdgatYdiykstrvnqpsieGtatfqqywSvrqskrtsgtitvanhfkaWaslGlklgklnyqvlavEgyqssGsasi 177
                     +tsdg+tY+++++tr+n+psi Gtatf+qy+S+r+s+rtsgt+t++nhf++WaslG++lg++nyqv+avEg++ssGsas 
      EEA21534.1 147 FTSDGSTYTVWENTRTNEPSIVGTATFNQYISIRSSTRTSGTVTIQNHFQEWASLGMNLGTMNYQVMAVEGWSSSGSASQ 226
                     *****************************************************************************985 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 0.64
                     CSSEEEEEEEESS-TT-EEEEEEE CS
  Glyco_hydro_11  32 nagnfvvgkGwnpgskrtikYsgt 55 
                     +     +g+Gw+  ++ +  Y++t
      EEA21534.1 260 Q----CGGQGWTGATACVSPYKCT 279
                     4....5799999777777777765 PP

>> CBM_1  Fungal cellulose binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   1.3      0.93   8.3e+03       7      14 ..      89      97 ..      89      98 .. 0.78
   2 !   49.9  12.6   2.5e-17   2.2e-13       1      29 []     257     285 ..     257     285 .. 0.99

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 0.93
       CBM_1  7 GigW.tGpT 14
                G gW tG T
  EEA21534.1 89 GVGWqTGTT 97
                789988877 PP

  == domain 2  score: 49.9 bits;  conditional E-value: 2.5e-17
       CBM_1   1 lwgQCGGigWtGpTtCvsgatCtyqNeyY 29 
                 +wgQCGG+gWtG+T+Cvs+++Ct+ N+yY
  EEA21534.1 257 QWGQCGGQGWTGATACVSPYKCTVINPYY 285
                 7**************************** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (289 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       514  (0.0286686); expected 358.6 (0.02)
Passed bias filter:                      267  (0.0148921); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 1970.31
//
Query:       EEA21535.1  [L=288]
Description: acetyl xylan esterase (Axe1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.5e-51  174.8   7.5    1.9e-51  174.6   7.5    1.1  1  Cutinase       Cutinase
    3.2e-12   46.2  14.8    3.2e-12   46.2  14.8    4.2  5  CBM_1          Fungal cellulose binding domain
    5.6e-05   22.8   0.8    7.7e-05   22.3   0.8    1.2  1  PE-PPE         PE-PPE domain
  ------ inclusion threshold ------
      0.054   13.1   0.1      0.083   12.5   0.1    1.2  1  Abhydrolase_1  alpha/beta hydrolase fold
       0.18   11.1   0.1       0.27   10.5   0.1    1.3  1  Hydrolase_4    Serine aminopeptidase, S33
        4.6    7.6  10.8          2    8.7   0.5    2.9  3  Toxin_7        Toxin 7


Domain annotation for each model (and alignments):
>> Cutinase  Cutinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  174.6   7.5   6.3e-55   1.9e-51       1     178 []      25     230 ..      25     230 .. 0.97

  Alignments for each domain:
  == domain 1  score: 174.6 bits;  conditional E-value: 6.3e-55
                 ---SEEEEEE--TT--TTTSSHHHHHHHHHHHH.TTT-EEEEE------CGG......STTSS-HHHHHHHHHHHHHHHHH-TT-EEEEEEETHHHHHH CS
    Cutinase   1 sckdvevifArgttepgglgsvGeavvsalesavgsksvavqgvnYpAdleq......lyegseeagakeaaalvqslaskCPdtkivlgGYSqGaqvi 93 
                 +c++++v++Ar+tt ++g+gs+ ++v+++l++++gs+++a++   YpA+ +q      +y+ s ++g++++a++v+s++s+CP+t+ivl+GYSqG++++
  EEA21535.1  25 ACPNIHVFGARETTASPGYGSSDTVVNDVLNAYPGSTAEAIV---YPACGGQsscggaSYSSSVAQGIAAVASAVNSFHSQCPNTEIVLVGYSQGGEIM 120
                 6*****************************************...****************************************************** PP

                 HHHHTT...............S-HHHHHHEEEEEEES-TTCCCCTT................S-TTS-GGGEEEE--TT-GGGTS----GGGG-GGGG. CS
    Cutinase  94 dnaiegga........tat..lpaavadkvaavvlfGdpsnvaglp................evsklyaskikslCdagDpiCgsgneleaHlsYvsey 166
                 d a++gg         t +  l+a++   v+a++++Gdp  +aglp                ++s+++as i+s+Cda+Dp+C++gn+ ++H++Y++ey
  EEA21535.1 121 DVALCGGGdsnqgytnT-AvqLSASAVTMVKAAIFMGDPLFRAGLPyevgtctaggfderpaGFSCPSASLIQSYCDASDPYCCNGNNSATHQGYGAEY 218
                 ******99999999752.257****************************************************************************** PP

                 HHHHHHHHHHH- CS
    Cutinase 167 ttqaakFvvskl 178
                 ++qa++F++ kl
  EEA21535.1 219 GNQALTFIKGKL 230
                 ********9875 PP

>> CBM_1  Fungal cellulose binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   1.7      0.21   6.4e+02       5      11 ..      76      82 ..      66      86 .. 0.80
   2 ?   -3.5   0.8       3.6   1.1e+04       5       8 ..     125     128 ..     125     135 .. 0.66
   3 ?   -3.9   0.2       4.7   1.4e+04      15      19 ..     170     174 ..     169     174 .. 0.57
   4 ?   -2.8   1.1       2.2   6.6e+03      21      28 ..     194     201 ..     183     207 .. 0.70
   5 !   46.2  14.8   1.1e-15   3.2e-12       1      29 []     256     284 ..     256     284 .. 0.99

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.21
       CBM_1  5 CGGigWt 11
                CGG +++
  EEA21535.1 76 CGGASYS 82
                8888887 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 3.6
       CBM_1   5 CGGi 8  
                 CGG 
  EEA21535.1 125 CGGG 128
                 9883 PP

  == domain 3  score: -3.9 bits;  conditional E-value: 4.7
       CBM_1  15 tCvsg 19 
                 tC++g
  EEA21535.1 170 TCTAG 174
                 56655 PP

  == domain 4  score: -2.8 bits;  conditional E-value: 2.2
       CBM_1  21 tCtyqNey 28 
                  C ++++y
  EEA21535.1 194 YCDASDPY 201
                 56666666 PP

  == domain 5  score: 46.2 bits;  conditional E-value: 1.1e-15
       CBM_1   1 lwgQCGGigWtGpTtCvsgatCtyqNeyY 29 
                 +wgQCGG+gWtG+T Cvs++tCt+ N+yY
  EEA21535.1 256 QWGQCGGQGWTGATGCVSPYTCTVINPYY 284
                 7**************************** PP

>> PE-PPE  PE-PPE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.3   0.8   2.6e-08   7.7e-05       1      65 [.      58     123 ..      58     145 .. 0.88

  Alignments for each domain:
  == domain 1  score: 22.3 bits;  conditional E-value: 2.6e-08
      PE-PPE   1 PgadaelvsyPasflpvtglksltvdeSvaeGtenLeaairaela..agekvvvfGySqgalvasne 65 
                 Pg +ae++ yPa     ++ +  ++ +Sva+G++ + +a++++++     ++v +GySqg+ +++ +
  EEA21535.1  58 PGSTAEAIVYPACGGQ-SSCGGASYSSSVAQGIAAVASAVNSFHSqcPNTEIVLVGYSQGGEIMDVA 123
                 788999*****97777.67999*******************9876547778**********999865 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.1   2.8e-05     0.083      38      87 ..      41     120 ..      38     125 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 2.8e-05
                    TTSTTSSSTTTGB.CHH..............................SHHHHHHHHHHHHHHCTTSSEEEEEETHHHHHH CS
  Abhydrolase_1  38 rGvgySspapacinddy..............................gtasvaddldrildalgddkltlvGhSmGGmia 87 
                    +G+g+S++  + + + y                              g+a+va  ++ +  + ++ +++lvG+S+GG i+
     EEA21535.1  41 PGYGSSDTVVNDVLNAYpgstaeaivypacggqsscggasysssvaqGIAAVASAVNSFHSQCPNTEIVLVGYSQGGEIM 120
                    677777777776665556666666666777777777777777777889999**************************997 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.1     9e-05      0.27      44      94 ..      73     124 ..      43     158 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 9e-05
  Hydrolase_4  44 rse.gkrghvpsfddyvdDlaafvekvkeehpelplfllGhSmGGliallyl 94 
                  +s  g   + +s+ + ++ +a++v+ + ++ p+++++l+G S GG i   +l
   EEA21535.1  73 QSScGGASYSSSVAQGIAAVASAVNSFHSQCPNTEIVLVGYSQGGEIMDVAL 124
                  444499999************************************9975555 PP

>> Toxin_7  Toxin 7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.1      0.92   2.8e+03      20      33 ..     182     195 ..     181     196 .. 0.87
   2 ?    3.3   2.5     0.033        99      11      20 ..     196     205 ..     192     208 .. 0.85
   3 ?    8.7   0.5   0.00068         2      17      34 .]     271     288 .]     264     288 .] 0.90

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.92
     Toxin_7  20 GlkCkelsipdsiC 33 
                 G+ C   s  +s C
  EEA21535.1 182 GFSCPSASLIQSYC 195
                 99999999999999 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.033
     Toxin_7  11 alagPrCCsG 20 
                 + + P+CC+G
  EEA21535.1 196 DASDPYCCNG 205
                 5689****98 PP

  == domain 3  score: 8.7 bits;  conditional E-value: 0.00068
     Toxin_7  17 CCsGlkCkelsipdsiCl 34 
                 C s+++C+  +   s Cl
  EEA21535.1 271 CVSPYTCTVINPYYSQCL 288
                 99***************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (288 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       431  (0.0240393); expected 358.6 (0.02)
Passed bias filter:                      244  (0.0136092); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 1906.28
//
Query:       EEA21536.1  [L=848]
Description: calpain-like protease PalBory [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.7e-30  104.1   0.0      1e-29  103.5   0.0    1.2  1  Peptidase_C2  Calpain family cysteine protease
    1.1e-06   28.9   0.0    1.6e-05   25.2   0.0    2.6  2  Calpain_III   Calpain large subunit, domain III
     0.0016   18.5   1.1     0.0027   17.7   1.1    1.3  1  MIT           MIT (microtubule interacting and transport) dom


Domain annotation for each model (and alignments):
>> Peptidase_C2  Calpain family cysteine protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.5   0.0   1.7e-33     1e-29      10     293 ..     145     434 ..     138     437 .. 0.76

  Alignments for each domain:
  == domain 1  score: 103.5 bits;  conditional E-value: 1.7e-33
  Peptidase_C2  10 esslfykkskkkkkkveWkRpkeive.......npk.fi.vdgasrtdikqGelgdCwllaaiasltlkekllkrvvpkeq........sf.eekya 88 
                   + sl +    +k+    WkRp e+v+       +pk    ++  + +d+ q    dC ++a+i++ t++ +  ++ + ++         ++ +++  
    EEA21536.1 145 TLSLSVP---QKEVFNGWKRPAELVKersqgniTPKkPNpAGTKKVMDLVQDITTDCSVIASICAATSRFERGHEFLFRNAifpfdyikNIpDTSIS 238
                   4444442...2334568********9999998833323325667889********************987766665555554444445434445899 PP

  Peptidase_C2  89 GifhfrfwrfgewvdvvvDDrlPt.vngklvf.vksaeknefWsalleKAyAklhgsyealkggstsealedftggvtesiel.elkeapkelfkil 182
                   G + frf+ +g + +vv+DDrlP  ++ + +f   ++  + fW al+eKAy kl g y+   g ++   l  +tg + e+i l +++ ap++l+  +
    EEA21536.1 239 GKYIFRFYFNGCYRKVVIDDRLPSsKSSRSLFaFDRNAPESFWPALIEKAYLKLRGGYD-FPGSNSGTDLWILTGWIPEQIFLhHEDVAPDQLWGRI 334
                   ***********************95445667757888899******************8.889999999************99544557788***** PP

  Peptidase_C2 183 kkalergslmgcsieassaeeleaklengLvkgHaYsvtaveevelkkekvkLirlrnPWGeveWkGawsdkskeWeevseeekeklklkkkedgef 279
                     a++ g ++ +  + +  ++ e+   +gL+ +H Y+v++++e +   +  + + ++nPW++ + + ++s +  + ++       + +++    g f
    EEA21536.1 335 LGAFQYGDIVLTLGTGEL-NSREE-RLQGLIGRHDYAVLDLNESD---G-YRRLLIKNPWADSSSRTPHSYSRASEQS-----ALDTTSTPLLPGSF 420
                   ***999999988776333.44444.479**************984...2.3344589****99888887766544333.....33333344457*** PP

  Peptidase_C2 280 wmsfedflknFtkl 293
                   wm+++++++nF+++
    EEA21536.1 421 WMDYDQVFQNFNNM 434
                   ***********987 PP

>> Calpain_III  Calpain large subunit, domain III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       1.8   1.1e+04      19      29 ..     465     475 ..     462     506 .. 0.79
   2 !   25.2   0.0   2.7e-09   1.6e-05       2     140 ..     590     702 ..     589     703 .. 0.77

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 1.8
  Calpain_III  19 fwkNPqfrlel 29 
                  f+++Pqf+++ 
   EEA21536.1 465 FANSPQFSIST 475
                  78889998864 PP

  == domain 2  score: 25.2 bits;  conditional E-value: 2.7e-09
  Calpain_III   2 eWvkgstAGGcrnkketfwkNPqfrleleeeededeeekkctvlvslmqknrrkerkkgeelltigfavykveeeeenrklrkeffaknqevarsstf 99 
                  eW +  tAGG++ ++  + +NPq  l++++         +  v++ l           +e+ l++  +++  ++    +  r + ++k++ v+ s ++
   EEA21536.1 590 EW-SPVTAGGNT-ESPRYPSNPQHVLQISD---------TADVVILLEA---------SEPGLAVHAKLFW-SD---GQ--RVSTVKKRDIVTDSGHY 661
                  57.6679***75.6899***********88.........3666666655.........3566888888888.23...23..33334556667778888 PP

  Calpain_III 100 insrevvkrfklppGeYvivPstfepneegeFlLrvFsekk 140
                       v +  kl+pG+Y +v stf p + ++F + vFs k+
   EEA21536.1 662 RPGCVVAETEKLRPGSYTLVCSTFLPDQVAKFNICVFSTKP 702
                  8888888888****************************986 PP

>> MIT  MIT (microtubule interacting and transport) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   1.1   4.5e-07    0.0027      17      64 ..      27      75 ..      15      76 .. 0.92

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 4.5e-07
         MIT 17 agnyeeAlelYkealelLlqalk.ekneerrellrekieeYleRaeeLk 64
                ag  +eAle+   a e  + alk  ++++ ++ l +k++ +++Rae++k
  EEA21536.1 27 AGTQSEALEAAIAAAENYMRALKlADTPREKQYLDSKCKDWISRAEKIK 75
                567789999999***********55999*******************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (848 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       433  (0.0241508); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.67u 0.27s 00:00:00.94 Elapsed: 00:00:00.44
# Mc/sec: 5792.66
//
Query:       EEA21537.1  [L=393]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.4e-58  194.6   1.8      1e-57  194.2   0.4    1.8  2  Vta1      Vta1 like
      5e-18   64.5   0.2    1.3e-17   63.2   0.2    1.8  1  Vta1_C    Vta1 C-terminal domain


Domain annotation for each model (and alignments):
>> Vta1  Vta1 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  194.2   0.4   1.1e-61     1e-57       2     145 .]      14     157 ..      13     157 .. 0.99
   2 ?   -1.0   0.0      0.17   1.5e+03     121     137 ..     353     369 ..     344     372 .. 0.81

  Alignments for each domain:
  == domain 1  score: 194.2 bits;  conditional E-value: 1.1e-61
        Vta1   2 iapflkrakelekadpvvaYycrlyaveqilkkklkrkdkeakefltkLldklEqlKkelkendaiedeeaakayvenfalklfnkadkedragkatka 100
                 i +f++ra+++e+a+pv+aY+c++++v+qi++k+l+++d e+++f+t+L+dklE++K+e+ +ndai+d+ a++ayve+f l++f++ad+++ra+katk+
  EEA21537.1  14 IGRFVTRAAQIERAKPVIAYWCNYWVVNQIISKGLHSTDAESTQFTTDLMDKLERFKSENPDNDAITDNVAGQAYVEQFGLEVFTRADNAVRANKATKQ 112
                 889************************************************************************************************ PP

        Vta1 101 taktflaaatlfevlklfgeldeeikkkikyakwkaarilkalke 145
                 ta+tflaaat++e+++++g++d +i++kik+ak++a+ri+ka+k+
  EEA21537.1 113 TADTFLAAATFLELCQIWGDVDPDITSKIKFAKYHAVRIAKAIKN 157
                 *******************************************97 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.17
        Vta1 121 ldeeikkkikyakwkaa 137
                 +d+ i++ +k+a+w ++
  EEA21537.1 353 DDQAITQAQKHARWAVS 369
                 588999********876 PP

>> Vta1_C  Vta1 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.2   0.2   1.4e-21   1.3e-17       2      38 .]     355     391 ..     354     391 .. 0.96

  Alignments for each domain:
  == domain 1  score: 63.2 bits;  conditional E-value: 1.4e-21
      Vta1_C   2 eqiaeAqKhaKfAiSALqYeDvetAiknLqeALklLt 38 
                 ++i++AqKha++A+SAL ++Dv+tAik+L++AL lL+
  EEA21537.1 355 QAITQAQKHARWAVSALSFDDVPTAIKELKNALQLLG 391
                 789********************************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (393 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       645  (0.0359752); expected 358.6 (0.02)
Passed bias filter:                      391  (0.0218082); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.22s 00:00:00.71 Elapsed: 00:00:00.39
# Mc/sec: 3051.79
//
Query:       EEA21538.1  [L=331]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-34  118.4   2.8    2.5e-34  118.3   0.8    1.9  2  Vta1      Vta1 like
    3.8e-18   64.9   0.2      1e-17   63.5   0.2    1.8  1  Vta1_C    Vta1 C-terminal domain


Domain annotation for each model (and alignments):
>> Vta1  Vta1 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.3   0.8   2.8e-38   2.5e-34      51     145 .]       1      95 [.       1      95 [. 0.99
   2 ?   -0.7   0.0      0.14   1.3e+03     121     137 ..     291     307 ..     282     310 .. 0.81

  Alignments for each domain:
  == domain 1  score: 118.3 bits;  conditional E-value: 2.8e-38
        Vta1  51 ldklEqlKkelkendaiedeeaakayvenfalklfnkadkedragkatkataktflaaatlfevlklfgeldeeikkkikyakwkaarilkalke 145
                 +dklE++K+e+ +ndai+d+ a++ayve+f l++f++ad+++ra+katk+ta+tflaaat++e+++++g++d +i++kik+ak++a+ri+ka+k+
  EEA21538.1   1 MDKLERFKSENPDNDAITDNVAGQAYVEQFGLEVFTRADNAVRANKATKQTADTFLAAATFLELCQIWGDVDPDITSKIKFAKYHAVRIAKAIKN 95 
                 9********************************************************************************************97 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.14
        Vta1 121 ldeeikkkikyakwkaa 137
                 +d+ i++ +k+a+w ++
  EEA21538.1 291 DDQAITQAQKHARWAVS 307
                 588999********876 PP

>> Vta1_C  Vta1 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.5   0.2   1.1e-21     1e-17       2      38 .]     293     329 ..     292     329 .. 0.96

  Alignments for each domain:
  == domain 1  score: 63.5 bits;  conditional E-value: 1.1e-21
      Vta1_C   2 eqiaeAqKhaKfAiSALqYeDvetAiknLqeALklLt 38 
                 ++i++AqKha++A+SAL ++Dv+tAik+L++AL lL+
  EEA21538.1 293 QAITQAQKHARWAVSALSFDDVPTAIKELKNALQLLG 329
                 789********************************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (331 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       647  (0.0360868); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.24s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 2219.42
//
Query:       EEA21539.1  [L=372]
Description: epimerase/dehydratase family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.8e-18   65.2   0.0      1e-17   64.4   0.0    1.3  1  Epimerase      NAD dependent epimerase/dehydratase family
    2.9e-12   46.3   0.0    4.1e-12   45.8   0.0    1.2  1  RmlD_sub_bind  RmlD substrate binding domain
    2.3e-06   26.9   0.0    6.7e-05   22.0   0.0    2.1  1  3Beta_HSD      3-beta hydroxysteroid dehydrogenase/isomerase 
    0.00044   19.7   0.0    0.00086   18.8   0.0    1.6  1  GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
  ------ inclusion threshold ------
      0.018   15.1   0.0      0.032   14.3   0.0    1.4  1  Ldh_1_N        lactate/malate dehydrogenase, NAD binding doma
      0.034   14.1   0.0      0.072   13.0   0.0    1.5  1  KR             KR domain


Domain annotation for each model (and alignments):
>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.4   0.0   3.4e-21     1e-17       1     239 [.       8     250 ..       8     251 .. 0.80

  Alignments for each domain:
  == domain 1  score: 64.4 bits;  conditional E-value: 3.4e-21
                 EEEETTTSHHHHHHHHHHHHCT..SEEEEEES-STTTTCHHCHHC........EEEE--TT-HHHHHHHHHHH...T-SEEEE--S---HHHHHHSHHH CS
   Epimerase   1 ilVtGatGfiGsalvkallekg..yevigldrlssasntarledl........elveldltdrsalerlfkee...qpdavihlAavggvaassedpad 86 
                 +l++G+ Gf+G++l+ ++ +++   e+  +d+l  + ++  l+          ++v++d   +++  r+f++    q+d+vi++A+    + + ++p++
  EEA21539.1   8 VLIIGGLGFVGRHLALHIHKNNlaSELRIVDKLLPQLAW--LAPEfeeacskeQFVQADASREQSYPRIFDRAdgkQFDYVINCAG----DLRLSQPEE 100
                 79********************9788*******444444..44445799***************9999999865569*******66....666778888 PP

                 HHH.HHTHHHHHHHHHHHHHTCTEEEEEEEGGGGTSCSSSSBSTCSTTS----SSHHHHHHHHHHHHHHHHHHHHT-EEEEEEESEEESTTS-TTSTTS CS
   Epimerase  87 fie.knlqgtlnlleaarkagvkrllflsSsevYGkdaeqpkeettltgplkpnspYaaaKlageklveayaaqyglnaiilrlfnlyGprngegevsr 184
                 +++ +n +++  l+++++k+g+  ++++s+s vY  + + p +e+ +++p+++        l +e+ + +     gln ++lrl ++yG++  ++  + 
  EEA21539.1 101 VYQlRNHAMSIGLAKEVSKRGIAVYVQASTSYVYKGSSK-PAKEDDKKKPWNTLAKWQ---LKVEEDLPS---VEGLNWVSLRLPHIYGEY--DRGYTA 190
                 88879*****************************98887.999999777777766666...555555555...589***************..555666 PP

                 HHHHHHHHHHTTSSSEEEETTST-EEEEEEHHHHHHHHHHHHHHHTT-ST......TEEEE CS
   Epimerase 185 vipalirkilegkqevtllgdgtalRdflyveDvaeaillvlehvdagdk......geiyn 239
                 v   l+r  +  + e+  l + + +   l+v+D+a+a+++++   +ag+k      ++i+n
  EEA21539.1 191 VAISLARTHQYLQTEFDQLESKDLKLNTLHVKDAARALWTAAVW-RAGQKanptagPHIFN 250
                 66555554444446999999*******************99877.3334445555555666 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.8   0.0   1.4e-15   4.1e-12       3     182 ..       8     211 ..       6     283 .. 0.78

  Alignments for each domain:
  == domain 1  score: 45.8 bits;  conditional E-value: 1.4e-15
                    EEEESTTSHHHHHHHHHCTTTSEEEEEE-TT..........................T--TTSHHHHHHHH...HHH--SEEEE------HHHHHH CS
  RmlD_sub_bind   3 ilvtGanGqlGseLakqlaeeglevlaltre..........................eldltdaeavaell...keakpdvvvnaAAytavDkaEs 69 
                    +l++G+ G +G++La  +++++l+    + +                          ++d +++++  +++   + ++ d v+n+A   +  + E+
     EEA21539.1   8 VLIIGGLGFVGRHLALHIHKNNLAS---ELRivdkllpqlawlapefeeacskeqfvQADASREQSYPRIFdraDGKQFDYVINCAGDLRLSQPEE 100
                    7899999999999999999887432...222244679999999999999999999999********99999443446788******9888888777 PP

                    SHHHHHHHHTHHHHHHHHHHHHCT-EE.EEEEEGGGS-S-TTS-B-TTS----SSHHHHHHHHHHHHHHH.H-SSEEEEEE-SEESSSSS-HHHHH CS
  RmlD_sub_bind  70 eeeaayavnaeavealAeaaaavgalL.ihvStDyVFdGekkrpYeeddetsPlnvYGrtKlaGEqavla.agkkalivRtswvygekgknfvktm 163
                      +++   n   +  lA++ +++g+ + ++ St yV+ G+ ++p +edd+++P n+ ++ +l+ E+   + +g +++ +R + +yge+++ + ++ 
     EEA21539.1 101 VYQLR---NHAMSIGLAKEVSKRGIAVyVQASTSYVYKGS-SKPAKEDDKKKPWNTLAKWQLKVEEDLPSvEGLNWVSLRLPHIYGEYDRGYTAVA 192
                    77666...445566799**9999987559**********9.7789*********************999967889999****************** PP

                    HHHHHH-SEEEEESS-EE- CS
  RmlD_sub_bind 164 lrlakereelkvvaDqlgs 182
                    ++la++++ l+   Dql s
     EEA21539.1 193 ISLARTHQYLQTEFDQLES 211
                    ************9999864 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.0   0.0   2.2e-08   6.7e-05       1     203 [.       9     202 ..       9     277 .. 0.65

  Alignments for each domain:
  == domain 1  score: 22.0 bits;  conditional E-value: 2.2e-08
   3Beta_HSD   1 vvtGgaGFlGralvkeLvrleelkevrvlD..lrespelleelskvnvkk.viegDvtdkdkleeal...egvdvvihlaslvdvagkltedeimkvnv 93 
                 +++Gg GF+Gr+l  ++ + + + e+r++D  l +  +l  e+++   k+ ++++D   +++  +     +g +   ++ ++ d++  + e+ ++  n 
  EEA21539.1   9 LIIGGLGFVGRHLALHIHKNNLASELRIVDklLPQLAWLAPEFEEACSKEqFVQADASREQSYPRIFdraDGKQFDYVINCAGDLRLSQPEEVYQLRNH 107
                 69**************999999********7656667777777665544449*****998876666511156677788999999999777776666666 PP

   3Beta_HSD  94 kGTrnvleacvkagvrvlvYtSsaevvgpnslgeeilngdEeleyeslhqdaypesKalaEklvlkaNgrtlknggrlyTcaLRpagiyGegdkllvpl 192
                      + +   k g+ v v  S+  v  +   +++  + d ++     + +++++     E+ + +  g        l+ ++LR   iyGe+d+  +++
  EEA21539.1 108 AMSIGLAKEVSKRGIAVYVQASTSYVYKG--SSKPAKEDDKKK-----PWNTLAKWQLKVEEDLPSVEG--------LNWVSLRLPHIYGEYDRGYTAV 191
                 66677777888899999998888887766..566666333333.....333444444444554444444........7778888888888888877777 PP

   3Beta_HSD 193 lkqlaklglal 203
                 +  la++++ l
  EEA21539.1 192 AISLARTHQYL 202
                 77777666443 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.0   2.9e-07   0.00086       1     152 [.       9     152 ..       9     269 .. 0.73

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 2.9e-07
                    EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHHHH...T-SEEEE--S---HHHHTT CS
  GDP_Man_Dehyd   1 LiTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkgDltDssslerllaev...qpdevynLAAqshVdvsfe 93 
                    Li G+ Gf+G +la ++ +++      + ++ + +++ ++   ++    + ++ +++++D + ++s  r+++++   q+d v+n A+       ++
     EEA21539.1   9 LIIGGLGFVGRHLALHIHKNNLASELRIVDKLLPQLAWLAPEFEE----ACSKEQFVQADASREQSYPRIFDRAdgkQFDYVINCAGD----LRLS 96 
                    89****************998777666666666676677665543....335779*****************987779********95....5677 PP

                    SHHHHHHHHTHHHHHHHHHHHHCT..TTSEEEEEEEGGGG.-S-SSSSB-TTS-----SH CS
  GDP_Man_Dehyd  94 kPeytaevnvlGtlrLLeairalglekkvrfyqaStsEvY.GkvqevpqtEttpfyPrsP 152
                    +Pe++++    ++   + +++++  +  + ++qaSts vY G  ++ p +E+ + +P + 
     EEA21539.1  97 QPEEVYQLRNHAMS--IGLAKEVSKRGIAVYVQASTSYVYkG--SSKPAKEDDKKKPWNT 152
                    89999998766654..4556666655668999********44..4568888888887665 PP

>> Ldh_1_N  lactate/malate dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   1.1e-05     0.032       3      34 ..       8      39 ..       7      94 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 1.1e-05
                EEEETTTSHHHHHHHHHHHHTTSSSEEEEE-S CS
     Ldh_1_N  3 vavvGaaGgiGqslalllankkladelaLlDi 34
                v ++G  G++G +lal + +++la+el+++D 
  EEA21539.1  8 VLIIGGLGFVGRHLALHIHKNNLASELRIVDK 39
                7899999***********************95 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   2.4e-05     0.072       3      94 ..       8      95 ..       6     107 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 2.4e-05
                EEEETTTSHHHHHHHHHHHHHH.S-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE------- CS
          KR  3 ylitGGlGgLGlelarwlaekg.arhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrd 94
                +li+GGlG +G++la ++ ++  a++l ++ +     ++ + l  e+e+   + ++v+aD s +++  +++++++  +++   vi++Ag lr 
  EEA21539.1  8 VLIIGGLGFVGRHLALHIHKNNlASELRIVDKL---LPQLAWLAPEFEEACSKEQFVQADASREQSYPRIFDRAD--GKQFDYVINCAGDLRL 95
                79*****************9888*****99988...4555557799999999999*****************997..6779999999998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (372 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       491  (0.0273858); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 2391.01
//
Query:       EEA21540.1  [L=860]
Description: topoisomerase I [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.3e-98  327.9   4.7    2.3e-98  327.9   4.7    3.1  3  Topoisom_I_N  Eukaryotic DNA topoisomerase I, DNA binding fra
    3.8e-97  324.1   3.2    3.8e-97  324.1   3.2    2.2  2  Topoisom_I    Eukaryotic DNA topoisomerase I, catalytic core
      6e-34  115.8   1.3    2.4e-33  113.9   1.3    2.2  1  Topo_C_assoc  C-terminal topoisomerase domain


Domain annotation for each model (and alignments):
>> Topoisom_I_N  Eukaryotic DNA topoisomerase I, DNA binding fragment
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   2.3      0.55   3.3e+03      89     133 ..     121     165 ..     108     173 .. 0.65
   2 !  327.9   4.7  3.8e-102   2.3e-98       1     213 []     228     451 ..     228     451 .. 0.97
   3 ?   -7.2   7.6         3   1.8e+04      63     121 ..     706     764 ..     687     796 .. 0.50

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.55
                   HHHHHHHHHHHHTT-----HHHHHHHHHHHHHHHHEEEETTEEEE CS
  Topoisom_I_N  89 ikeylekekekkkaltkeekkklkeekekleekygyalldgrkek 133
                   i++ l+k+k++ ++++++e k++++++++ ++k + a  +g+k k
    EEA21540.1 121 IEHKLSKQKANIEKKAEHEAKAIRKAEATSSTKKASAAANGKKPK 165
                   555555666655556666666666666666666666777777666 PP

  == domain 2  score: 327.9 bits;  conditional E-value: 3.8e-102
                   ---S-EE----B---------TT--EEETTEEE---HHHHHHHHHHHHTTTSS.GGG-HHHHHHHHHHHHHHHHHTT-..........---GGGEE- CS
  Topoisom_I_N   1 vkWktLehnGvlfppeYeplpknvklkydgkpvkLspeaEEvatfyaamletd.yakkevFqknffkdfkkvlkekek..........ikelekcdF 86 
                   +kW+tLehnGv+fppeYeplpknvk+kydg pv L+peaEEva+f++aml+++ ++++++Fqknff+dfk++lk++            ike++kcdF
    EEA21540.1 228 IKWNTLEHNGVVFPPEYEPLPKNVKMKYDGVPVVLHPEAEEVAGFFGAMLNSThNVENPTFQKNFFEDFKAILKKTGGaktqkgepinIKEFKKCDF 324
                   69************************************************9774799****************8887767778888889******** PP

                   HHHHHHHHHHHHHHTT-----HHHHHHHHHHHHHHHHEEEETTEEEEEE--B----EE----TT-TTTT-EE----GGG-EEE--SSS-----STT- CS
  Topoisom_I_N  87 skikeylekekekkkaltkeekkklkeekekleekygyalldgrkekvgnfrvepPgLfrgrGehpktGklkkrvlpedvtiNigkdakvPeppagh 183
                   ++i+ey+e ++ +kk+l+++ekk+lk+e++++e++y+y+++dgrk+kvgnfrvepP+LfrgrGehpktGk+k+rv+pe++tiNigkdakvP+pp+gh
    EEA21540.1 325 KPIFEYYEGKRLEKKNLSAAEKKALKAERDEAEAPYMYCIWDGRKQKVGNFRVEPPSLFRGRGEHPKTGKVKTRVMPEQITINIGKDAKVPPPPEGH 421
                   ************************************************************************************************* PP

                   --SEEE--TT---SEEEE-TTT--EEEEEE CS
  Topoisom_I_N 184 kWkevvhdntvtwlaswkeningqvkyvmL 213
                   kWkev+hd++ twla+w+en+ng++kyvmL
    EEA21540.1 422 KWKEVRHDQEGTWLAMWQENVNGNYKYVML 451
                   *****************************8 PP

  == domain 3  score: -7.2 bits;  conditional E-value: 3
                   HHHHHHHHHH...HHTT----GGGEE-HHHHHHHHHHHHHHTT-----HHHHHHHHHHHHHH CS
  Topoisom_I_N  63 nffkdfkkvl...kekekikelekcdFskikeylekekekkkaltkeekkklkeekekleek 121
                    ++++ ++ l   ++++++k++ek d +k+++  + eke+k +  +e+   lk++++k +++
    EEA21540.1 706 AWIQEHQAFLieeQKQKITKKFEK-DNEKLAA--DGEKEMKPKELEERLAVLKDMEKKFQKE 764
                   455555555533122222233332.3333333..3333333333333333344443333333 PP

>> Topoisom_I  Eukaryotic DNA topoisomerase I, catalytic core
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  324.1   3.2  6.4e-101   3.8e-97       2     230 ..     455     679 ..     454     681 .. 0.98
   2 ?   -2.4   1.3      0.38   2.3e+03      93     128 ..     774     809 ..     729     819 .. 0.60

  Alignments for each domain:
  == domain 1  score: 324.1 bits;  conditional E-value: 6.4e-101
                 SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-S-HHHHHHHHHHHHHHHH---------TTS-----GGG-BGGGEEE-TT.SEEEEEEE-GGG-E CS
  Topoisom_I   2 sklkgekdfkKYekarkLkkvvekiredykkklkskeilekqlatavylidklaLrvGnekeeeeadtvGccsLrvehvklsekektitldFlGKdsir 100
                 s++kg++d+kK+ekar+Lkk+++kiredy+k lks+ ++++q+atavylidk+aLr+Gnek e+eadtvGccsL++e+++l+++ +t+ +dFlGKdsir
  EEA21540.1 455 SDIKGQSDYKKFEKARELKKHIDKIREDYRKGLKSDLMADRQRATAVYLIDKFALRAGNEKGEDEADTVGCCSLKYENISLRPP-NTVIFDFLGKDSIR 552
                 89*********************************************************************************9.************** PP

                 EEEEEE--HHHHHHHHHHHTT.--TTSBTTTT--HHHHHHHHTTTSTT--TTHHHHHHHHHHHHHHHHH..--------TTHHHHHHHHHHHHHHHHHT CS
  Topoisom_I 101 yfntvkvdkqvyknlkifckk.kkkgeevFdkintsklNkyLkelmegLsAKvFRTYnASitlqeqLkklekievdesnvaekikayneAnreVAilcn 198
                 ++++v+vd+qv+knlkif+k+ kk+g+e+Fd+++ts lNk+L+++m+gL+AKvFRTYnAS+t+ + Lk++    + e++vaek+k+yn+Anr+VAilcn
  EEA21540.1 553 FYDEVEVDPQVFKNLKIFKKApKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTFATLLKDM----KAEGTVAEKVKQYNDANRRVAILCN 647
                 *********************************************************************8....5899********************* PP

                 -EE-XXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Topoisom_I 199 hqrsvpkqheksmeklkkkiealkedikelkk 230
                 h+r+v+  h+++mekl ++i+ l+++++++k 
  EEA21540.1 648 HKRTVTAGHANQMEKLGDRIKGLRYQKWRVKM 679
                 **************************999876 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.38
                 EE-GGG-EEEEEEE--HHHHHHHHHHHTT--TTSBT CS
  Topoisom_I  93 FlGKdsiryfntvkvdkqvyknlkifckkkkkgeev 128
                  +G+   + +n+v+  +q  +n+++  ++k++++ev
  EEA21540.1 774 GKGQTVEKLENNVTKLEQRIENMSLQAEDKENNKEV 809
                 333333445555555556666666555555555554 PP

>> Topo_C_assoc  C-terminal topoisomerase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.9   1.3     4e-37   2.4e-33       1      70 []     790     860 .]     790     860 .] 0.98

  Alignments for each domain:
  == domain 1  score: 113.9 bits;  conditional E-value: 4e-37
  Topo_C_assoc   1 kekikklklqlkdkeenkevaLgtSkinYlDPRitvawckkhdvpiekiFsktlleKfaWAme.vdedfkf 70 
                   +++i++++lq++dke+nkevaLgtSkinY+DPR+tv+++kk++vpiek+Fsktl+eKf WA++ v+ed++f
    EEA21540.1 790 EQRIENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFTKKFNVPIEKFFSKTLREKFDWAIKsVEEDWEF 860
                   589******************************************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (860 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1835  (0.102348); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.83u 0.29s 00:00:01.11 Elapsed: 00:00:00.49
# Mc/sec: 5238.93
//
Query:       EEA21541.1  [L=860]
Description: topoisomerase I [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.3e-98  327.9   4.7    2.3e-98  327.9   4.7    3.1  3  Topoisom_I_N  Eukaryotic DNA topoisomerase I, DNA binding fra
    3.8e-97  324.1   3.2    3.8e-97  324.1   3.2    2.2  2  Topoisom_I    Eukaryotic DNA topoisomerase I, catalytic core
      6e-34  115.8   1.3    2.4e-33  113.9   1.3    2.2  1  Topo_C_assoc  C-terminal topoisomerase domain


Domain annotation for each model (and alignments):
>> Topoisom_I_N  Eukaryotic DNA topoisomerase I, DNA binding fragment
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   2.3      0.55   3.3e+03      89     133 ..     121     165 ..     108     173 .. 0.65
   2 !  327.9   4.7  3.8e-102   2.3e-98       1     213 []     228     451 ..     228     451 .. 0.97
   3 ?   -7.2   7.6         3   1.8e+04      63     121 ..     706     764 ..     687     796 .. 0.50

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.55
                   HHHHHHHHHHHHTT-----HHHHHHHHHHHHHHHHEEEETTEEEE CS
  Topoisom_I_N  89 ikeylekekekkkaltkeekkklkeekekleekygyalldgrkek 133
                   i++ l+k+k++ ++++++e k++++++++ ++k + a  +g+k k
    EEA21541.1 121 IEHKLSKQKANIEKKAEHEAKAIRKAEATSSTKKASAAANGKKPK 165
                   555555666655556666666666666666666666777777666 PP

  == domain 2  score: 327.9 bits;  conditional E-value: 3.8e-102
                   ---S-EE----B---------TT--EEETTEEE---HHHHHHHHHHHHTTTSS.GGG-HHHHHHHHHHHHHHHHHTT-..........---GGGEE- CS
  Topoisom_I_N   1 vkWktLehnGvlfppeYeplpknvklkydgkpvkLspeaEEvatfyaamletd.yakkevFqknffkdfkkvlkekek..........ikelekcdF 86 
                   +kW+tLehnGv+fppeYeplpknvk+kydg pv L+peaEEva+f++aml+++ ++++++Fqknff+dfk++lk++            ike++kcdF
    EEA21541.1 228 IKWNTLEHNGVVFPPEYEPLPKNVKMKYDGVPVVLHPEAEEVAGFFGAMLNSThNVENPTFQKNFFEDFKAILKKTGGaktqkgepinIKEFKKCDF 324
                   69************************************************9774799****************8887767778888889******** PP

                   HHHHHHHHHHHHHHTT-----HHHHHHHHHHHHHHHHEEEETTEEEEEE--B----EE----TT-TTTT-EE----GGG-EEE--SSS-----STT- CS
  Topoisom_I_N  87 skikeylekekekkkaltkeekkklkeekekleekygyalldgrkekvgnfrvepPgLfrgrGehpktGklkkrvlpedvtiNigkdakvPeppagh 183
                   ++i+ey+e ++ +kk+l+++ekk+lk+e++++e++y+y+++dgrk+kvgnfrvepP+LfrgrGehpktGk+k+rv+pe++tiNigkdakvP+pp+gh
    EEA21541.1 325 KPIFEYYEGKRLEKKNLSAAEKKALKAERDEAEAPYMYCIWDGRKQKVGNFRVEPPSLFRGRGEHPKTGKVKTRVMPEQITINIGKDAKVPPPPEGH 421
                   ************************************************************************************************* PP

                   --SEEE--TT---SEEEE-TTT--EEEEEE CS
  Topoisom_I_N 184 kWkevvhdntvtwlaswkeningqvkyvmL 213
                   kWkev+hd++ twla+w+en+ng++kyvmL
    EEA21541.1 422 KWKEVRHDQEGTWLAMWQENVNGNYKYVML 451
                   *****************************8 PP

  == domain 3  score: -7.2 bits;  conditional E-value: 3
                   HHHHHHHHHH...HHTT----GGGEE-HHHHHHHHHHHHHHTT-----HHHHHHHHHHHHHH CS
  Topoisom_I_N  63 nffkdfkkvl...kekekikelekcdFskikeylekekekkkaltkeekkklkeekekleek 121
                    ++++ ++ l   ++++++k++ek d +k+++  + eke+k +  +e+   lk++++k +++
    EEA21541.1 706 AWIQEHQAFLieeQKQKITKKFEK-DNEKLAA--DGEKEMKPKELEERLAVLKDMEKKFQKE 764
                   455555555533122222233332.3333333..3333333333333333344443333333 PP

>> Topoisom_I  Eukaryotic DNA topoisomerase I, catalytic core
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  324.1   3.2  6.4e-101   3.8e-97       2     230 ..     455     679 ..     454     681 .. 0.98
   2 ?   -2.4   1.3      0.38   2.3e+03      93     128 ..     774     809 ..     729     819 .. 0.60

  Alignments for each domain:
  == domain 1  score: 324.1 bits;  conditional E-value: 6.4e-101
                 SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-S-HHHHHHHHHHHHHHHH---------TTS-----GGG-BGGGEEE-TT.SEEEEEEE-GGG-E CS
  Topoisom_I   2 sklkgekdfkKYekarkLkkvvekiredykkklkskeilekqlatavylidklaLrvGnekeeeeadtvGccsLrvehvklsekektitldFlGKdsir 100
                 s++kg++d+kK+ekar+Lkk+++kiredy+k lks+ ++++q+atavylidk+aLr+Gnek e+eadtvGccsL++e+++l+++ +t+ +dFlGKdsir
  EEA21541.1 455 SDIKGQSDYKKFEKARELKKHIDKIREDYRKGLKSDLMADRQRATAVYLIDKFALRAGNEKGEDEADTVGCCSLKYENISLRPP-NTVIFDFLGKDSIR 552
                 89*********************************************************************************9.************** PP

                 EEEEEE--HHHHHHHHHHHTT.--TTSBTTTT--HHHHHHHHTTTSTT--TTHHHHHHHHHHHHHHHHH..--------TTHHHHHHHHHHHHHHHHHT CS
  Topoisom_I 101 yfntvkvdkqvyknlkifckk.kkkgeevFdkintsklNkyLkelmegLsAKvFRTYnASitlqeqLkklekievdesnvaekikayneAnreVAilcn 198
                 ++++v+vd+qv+knlkif+k+ kk+g+e+Fd+++ts lNk+L+++m+gL+AKvFRTYnAS+t+ + Lk++    + e++vaek+k+yn+Anr+VAilcn
  EEA21541.1 553 FYDEVEVDPQVFKNLKIFKKApKKEGDEIFDRLTTSALNKHLSNYMPGLTAKVFRTYNASYTFATLLKDM----KAEGTVAEKVKQYNDANRRVAILCN 647
                 *********************************************************************8....5899********************* PP

                 -EE-XXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Topoisom_I 199 hqrsvpkqheksmeklkkkiealkedikelkk 230
                 h+r+v+  h+++mekl ++i+ l+++++++k 
  EEA21541.1 648 HKRTVTAGHANQMEKLGDRIKGLRYQKWRVKM 679
                 **************************999876 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.38
                 EE-GGG-EEEEEEE--HHHHHHHHHHHTT--TTSBT CS
  Topoisom_I  93 FlGKdsiryfntvkvdkqvyknlkifckkkkkgeev 128
                  +G+   + +n+v+  +q  +n+++  ++k++++ev
  EEA21541.1 774 GKGQTVEKLENNVTKLEQRIENMSLQAEDKENNKEV 809
                 333333445555555556666666555555555554 PP

>> Topo_C_assoc  C-terminal topoisomerase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.9   1.3     4e-37   2.4e-33       1      70 []     790     860 .]     790     860 .] 0.98

  Alignments for each domain:
  == domain 1  score: 113.9 bits;  conditional E-value: 4e-37
  Topo_C_assoc   1 kekikklklqlkdkeenkevaLgtSkinYlDPRitvawckkhdvpiekiFsktlleKfaWAme.vdedfkf 70 
                   +++i++++lq++dke+nkevaLgtSkinY+DPR+tv+++kk++vpiek+Fsktl+eKf WA++ v+ed++f
    EEA21541.1 790 EQRIENMSLQAEDKENNKEVALGTSKINYIDPRLTVVFTKKFNVPIEKFFSKTLREKFDWAIKsVEEDWEF 860
                   589******************************************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (860 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1835  (0.102348); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.77u 0.27s 00:00:01.04 Elapsed: 00:00:00.45
# Mc/sec: 5694.56
//
Query:       EEA21542.1  [L=298]
Description: ATP synthase gamma chain, mitochondrial precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.8e-76  255.9   5.7    7.1e-76  255.6   5.7    1.0  1  ATP-synt    ATP synthase
  ------ inclusion threshold ------
       0.08   12.7   0.1         11    5.7   0.0    2.3  2  Chalcone_2  Chalcone isomerase like


Domain annotation for each model (and alignments):
>> ATP-synt  ATP synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  255.6   5.7   7.9e-80   7.1e-76       1     278 [.      30     294 ..      30     294 .. 0.90

  Alignments for each domain:
  == domain 1  score: 255.6 bits;  conditional E-value: 7.9e-80
                 THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTHHHHCEHHHHTTT..SSG.S..SSEEEEEEE--SSSSSTTHHHHHHHHHHH CS
    ATP-synt   1 slkeikrRiksvkstkkItkAmkmVaaaklrkaqealeaarpyaekleevlealakreeeekhpllkee.ekkvllivitSDrGLcGgfNsnvikkaek 98 
                 +l+ei+ R+ks+++++kIt++mk++a+++l++aq+a+e++r y+++ ++v+e+        ++p   ee +kk+l+iv +SD+GLcGg++s + k++++
  EEA21542.1  30 TLREIEGRLKSIRNIEKITNTMKVIASTRLTRAQKAMEDSRVYGKTSNAVFESAE------TKP---EEgDKKTLYIVASSDKGLCGGIHSGLSKATRR 119
                 69***************************************************92......233...344889************************54 PP

                 HHHHHHTTT.ETEEEEESHHHHHHH..HHSS.EHHTTCE-TS.S--HHHHHHHHHHHHSHHHTTSBSEEEEEEEEECCTSEEEEEEEEESST...HCS. CS
    ATP-synt  99 lieelkkeg.evklvvvGkkgreyf..krkvevqleftgvsk.kptfeeaseiaeeildlyeegeideveivynkfksaisqeptvekllplekeeekk 193
                 l +e    + +++lvv+G+k+++++  +++++++l+f++v k  ptf++a++ia+++       ++  ++i++nkf +a s+ept+   ++ e  +++ 
  EEA21542.1 120 LLAE----NpSADLVVLGEKAKAQLsrSNGQNIVLSFSQVCKdIPTFADAQAIADQVA--LLPTNYGTIKIIHNKFLNAQSYEPTTVDAYSEEAITNSP 212
                 4433....33579************855599********8888**************6..578899*************************65554333 PP

                 .SSTSEESS.HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT CS
    ATP-synt 194 ekseyefepdeeevleellpeylasliyrallesaasEqaaRmtaMdnAtknakelidkltleyNraRQaaITqELieIvsGaeA 278
                 + s   fe + ee le+l ++ la++++ a++e +a+E +aR++aM+nA+kna+e+i+k+++ yNr+RQaaIT EL+eI++Ga+A
  EEA21542.1 213 NIS--AFEVE-EEALENLREYALANSLFWAMAEGLACEISARRNAMENASKNAGEMIQKFQIMYNRQRQAAITGELVEIITGAAA 294
                 334..45444.77**********************************************************************98 PP

>> Chalcone_2  Chalcone isomerase like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.1    0.0023        21      78     117 ..       9      55 ..       3     102 .. 0.77
   2 ?    5.7   0.0    0.0012        11      97     146 ..     237     284 ..     204     291 .. 0.87

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0023
  Chalcone_2  78 lldegirtavrivPvrnTdfshLrD..Gfvraitarakkkk.....e 117
                  l++g ++++r +P+  ++f  Lr+  G  ++i +  k  +      
  EEA21542.1   9 ALKAGSTVVARTAPTNAANFATLREieGRLKSIRNIEKITNtmkviA 55 
                 5789999*****************76699998887655554444443 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.0012
  Chalcone_2  97 fshLrDGfvraitarakkkkeeeedeefgeslkefkslFnrkgsvpkgke 146
                 f  + +G+   i ar ++   e+ +++ ge++++f+ ++nr+++++ + e
  EEA21542.1 237 FWAMAEGLACEISARRNAM--ENASKNAGEMIQKFQIMYNRQRQAAITGE 284
                 67788999999****9999..799999************99887765555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (298 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       667  (0.0372023); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2218.60
//
Query:       EEA21543.1  [L=501]
Description: F-box domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.9e-06   27.6   0.0      6e-06   26.0   0.0    1.8  1  F-box       F-box domain
    3.8e-06   26.7   0.0    8.1e-06   25.6   0.0    1.5  1  F-box-like  F-box-like


Domain annotation for each model (and alignments):
>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0   0.0   6.6e-10     6e-06       6      40 ..      12      46 ..       9      51 .. 0.93

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 6.6e-10
                S-HHHHHHHHHTS-HHHHHHHCTT-HHHHHHHTTH CS
       F-box  6 LPsevlrhILerLplsdllalrrVSkgwrilidsd 40
                LP e+   I+++L ++dl+++r VS  w+++  ++
  EEA21543.1 12 LPQEIFQMIIQHLQPVDLVRCRGVSSAWYRAFTNP 46
                9****************************998776 PP

>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.0     9e-10   8.1e-06       2      36 ..      10      44 ..       9      48 .. 0.92

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 9e-10
  F-box-like  2 srLPdEiLlqIFsyLppsdLlrlalVCrrWrrval 36
                ++LP Ei   I ++L p dL+r++ V++ W+r+  
  EEA21543.1 10 AYLPQEIFQMIIQHLQPVDLVRCRGVSSAWYRAFT 44
                79******************************974 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (501 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       323  (0.0180155); expected 358.6 (0.02)
Passed bias filter:                      295  (0.0164538); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.23s 00:00:00.74 Elapsed: 00:00:00.40
# Mc/sec: 3739.28
//
Query:       EEA21544.1  [L=464]
Description: disulfide isomerase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.4e-33  113.4   0.0    3.7e-27   94.3   0.1    2.5  2  Thioredoxin    Thioredoxin
    1.4e-07   32.0   0.1     0.0073   16.7   0.1    2.5  2  Thioredoxin_2  Thioredoxin-like domain
    2.4e-07   30.4   0.0    1.5e-05   24.5   0.0    2.2  2  OST3_OST6      OST3 / OST6 family, transporter family
     0.0016   18.8   0.0        1.5    9.2   0.0    3.7  4  Thioredoxin_8  Thioredoxin-like
     0.0026   17.7   0.0       0.74    9.7   0.0    2.9  3  Thioredoxin_6  Thioredoxin-like domain
     0.0055   16.6   0.0      0.017   15.1   0.0    1.7  2  AhpC-TSA       AhpC/TSA family
     0.0087   16.2   0.0       0.02   15.1   0.0    1.6  1  Thioredoxin_7  Thioredoxin-like
  ------ inclusion threshold ------
      0.039   14.0   1.1        1.8    8.6   0.1    2.9  3  Thioredoxin_3  Thioredoxin domain
       0.17   11.7   0.0       0.17   11.7   0.0    3.8  4  TraF           F plasmid transfer operon protein


Domain annotation for each model (and alignments):
>> Thioredoxin  Thioredoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.3   0.1   1.9e-30   3.7e-27       2     101 ..      29     135 ..      28     137 .. 0.93
   2 !   16.5   0.0   3.1e-06    0.0062      42     101 ..     178     237 ..     171     239 .. 0.83

  Alignments for each domain:
  == domain 1  score: 94.3 bits;  conditional E-value: 1.9e-30
                  EEESSHHHHHHHHTTTSSEEEEEEE-TTSHHHHCHHHHHHHHHHHCTT..TSEEEEEETTTSHHHHHHTT-SSSSEEEEEETTE.....EEEEEESS- CS
  Thioredoxin   2 vlvltkenFeeevakekklvlveFyApwCghCkalaPeleklaeelkd..kvklakvdvdenedlakkyevegiPtlklfkngk.....evkkyegar 92 
                  vl++ ++nF++ ++k++++ +veFyApwCghC++l+P +ek+a++l++  kv  +++d den+ l+ +++v+g+Ptlk++  gk     +v++y+g+r
   EEA21544.1  29 VLQVDAKNFDSLINKSNHTSIVEFYAPWCGHCQNLKPAYEKAAKNLEGlaKVAAINCDDDENKPLCGQMGVQGFPTLKIVVPGKkpgkpRVEDYQGQR 126
                  678899******************************************989999999999********************999978778899****** PP

                  HHHHHHHHH CS
  Thioredoxin  93 ekeklaafl 101
                   ++++++ +
   EEA21544.1 127 AAKAIVDAV 135
                  *99999876 PP

  == domain 2  score: 16.5 bits;  conditional E-value: 3.1e-06
                  HHHHHCTTTSEEEEEETTTSHHHHHHTT-SSSSEEEEEETTE.EEEEEESS-HHHHHHHHH CS
  Thioredoxin  42 klaeelkdkvklakvdvdenedlakkyevegiPtlklfkngk.evkkyegarekeklaafl 101
                  +la ++ + + +a++  +e+ + +++++++++Ptl+l+++g  e+  yeg+ +k+ + +fl
   EEA21544.1 178 SLAIDFLGGINFAQIRSKES-KAVEQFGITSFPTLILLPAGGsEPVVYEGEMKKALMLEFL 237
                  56666667889999988777.77899*************999899******9988887776 PP

>> Thioredoxin_2  Thioredoxin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.1   3.7e-06    0.0073       4      99 ..      44     125 ..      41     135 .. 0.74
   2 !   13.0   0.0   5.4e-05      0.11      65     107 ..     185     235 ..     133     237 .. 0.71

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 3.7e-06
  Thioredoxin_2   4 ngkpvlvvftdpdCpyCkklkkelkel.ddvtvrvllfplkpsfepkavaiwcakekkkafkdieenvelarkygvrgtPt..ivfldgk....ei 92 
                    ++   +v f++p+C+ C+ lk   ++  ++++             +k++ai c+++++         + l  ++gv+g+Pt  i + +gk     +
     EEA21544.1  44 SNHTSIVEFYAPWCGHCQNLKPAYEKAaKNLEGL-----------AKVAAINCDDDEN---------KPLCGQMGVQGFPTlkI-VVPGKkpgkPR 118
                    56667899**************999994444444...........7888999999885.........889***********644.55555466656 PP

  Thioredoxin_2  93 varlpGy 99 
                    v+ ++G 
     EEA21544.1 119 VEDYQGQ 125
                    6666665 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 5.4e-05
  Thioredoxin_2  65 d.......ieenvelarkygvrgtPtivfldgk.eivarlpGyvpaeelea 107
                    +         ++++ ++++g++++Pt+++l++   +  +++G ++++ +++
     EEA21544.1 185 GginfaqiRSKESKAVEQFGITSFPTLILLPAGgSEPVVYEGEMKKALMLE 235
                    055555555677888899********99777777666699**999887766 PP

>> OST3_OST6  OST3 / OST6 family, transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.5   0.0   7.6e-09   1.5e-05       8     154 ..      24     156 ..      19     157 .. 0.88
   2 ?    3.6   0.0     0.018        35      76     135 ..     189     239 ..     177     254 .. 0.66

  Alignments for each domain:
  == domain 1  score: 24.5 bits;  conditional E-value: 7.6e-09
   OST3_OST6   8 kksngviklndenykellkgprdysvvvllTatspqfkCelCrefepefelvakswrkdekskskklfFakvdfdegkdvFqklglnsaPhlllfppkk 106
                  ks+ v++++ +n+++l++ + + + +v + a      C  C++++p +e+ ak           k+  ++ d de+k +  ++g++  P l ++ p k
  EEA21544.1  24 TKSSPVLQVDAKNFDSLIN-KSNHTSIVEFYAP----WCGHCQNLKPAYEKAAKNLEGL-----AKVAAINCDDDENKPLCGQMGVQGFPTLKIVVPGK 112
                 56679*************6.8999999999998....7*****************9999.....59*******************************88 PP

   OST3_OST6 107 gpkeskkkdtydfsrggfdaealakfisertgvkirikrppnyskiii 154
                 +p     k +++  +g+  a+a+++ + er+++ ++     +y+++i+
  EEA21544.1 113 KPG----KPRVEDYQGQRAAKAIVDAVVERIPNYVKKLTNKDYESWIA 156
                 887....55555556677999999999999999998888888888875 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.018
   OST3_OST6  76 FakvdfdegkdvFqklglnsaPhlllfppkkgpkeskkkdtydfsrggfdaealakfise 135
                 Fa++  +  ++ ++++g++s P l+l p+ ++     ++  y+    +++ + + +f+s+
  EEA21544.1 189 FAQIRSK-ESKAVEQFGITSFPTLILLPAGGS-----EPVVYEG---EMKKALMLEFLSQ 239
                 4444444.4567899**************543.....3333332...2222335555555 PP

>> Thioredoxin_8  Thioredoxin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.2   0.0   0.00074       1.5       5      48 ..      49      90 ..      45      91 .. 0.89
   2 ?    4.2   0.0     0.028        55      63      90 ..      82     109 ..      71     113 .. 0.85
   3 ?    3.3   0.0     0.052     1e+02      71      90 ..     196     215 ..     187     220 .. 0.78
   4 ?   -0.8   0.0         1     2e+03      57      93 ..     359     395 ..     347     396 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00074
                   EEEE--SSSHHHHHHHHHHHHHHHHHHHTTSEEEEEEE-SS-HH CS
  Thioredoxin_8  5 lLyfgaswcppckaftpklkelyeklkkkkkveivyvsldkkee 48
                   ++ f+a wc +c++  p   +  ++l+     ++ ++++d +e+
     EEA21544.1 49 IVEFYAPWCGHCQNLKPAYEKAAKNLE--GLAKVAAINCDDDEN 90
                   788***********************9..888899999999987 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.028
                    E.EE-TT-HHHHTT-S--TT-SEEEEE- CS
  Thioredoxin_8  63 svpfddkkrnklkkkynvkaiPtlvvld 90 
                    ++  dd++++ l+ +++v+++Ptl ++ 
     EEA21544.1  82 AINCDDDENKPLCGQMGVQGFPTLKIVV 109
                    67789999***************98875 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.052
                    HHHHTT-S--TT-SEEEEE- CS
  Thioredoxin_8  71 rnklkkkynvkaiPtlvvld 90 
                     +k  ++++++++Ptl++l 
     EEA21544.1 196 ESKAVEQFGITSFPTLILLP 215
                    4566789***********96 PP

  == domain 4  score: -0.8 bits;  conditional E-value: 1
                    S-TTSEE.EE-TT-HHHHTT-S--TT-SEEEEE-TT- CS
  Thioredoxin_8  57 nkkpwlsvpfddkkrnklkkkynvkaiPtlvvldkng 93 
                    ++ p++svp  +   + l+ ++++++  t+ ++  ng
     EEA21544.1 359 HHLPFYSVPAINSHAKILRTELGLSETSTTEIIAVNG 395
                    3579999999999999999999999999999988777 PP

>> Thioredoxin_6  Thioredoxin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0      0.02        41      78     155 ..      28     105 ..      24     116 .. 0.81
   2 !    9.7   0.0   0.00037      0.74      10      73 ..     174     239 ..     166     244 .. 0.79
   3 ?   -1.4   0.0      0.91   1.8e+03     108     183 ..     340     419 ..     334     420 .. 0.72

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.02
                    SEEE-SHHHHHHHHTSS--EEEEEEE-TTSTTHHHHHHHHHHHHHHTTTT-EEEEEETT..GGHHHHHHTT--GGG-SEE CS
  Thioredoxin_6  78 lvreltpenaeelfeeglppllllflkkddeeteklkkaiekvakefkdkinfaladak..sfkrpleylglsssdlPvi 155
                    +v +++ +n++ l+++   + ++ f+       + lk a+ek+ak++++  ++a ++++  ++k ++ ++g++    P++
     EEA21544.1  28 PVLQVDAKNFDSLINKSNHTSIVEFYAPWCGHCQNLKPAYEKAAKNLEGLAKVAAINCDddENKPLCGQMGVQ--GFPTL 105
                    567788999999999999999999997766666899999**********999999999996667777799999..55554 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.00037
                    HHHHHHTTT-T.TSEEEEE--HH..HHHHTT--S.SEEEEEETTTTEEEEEETHT--HHHHHHHHHH CS
  Thioredoxin_6  10 eiFekvakelkgdvrfgvtkske..vadklgvke.pavllfrkfdeekvkydgekitvddlkkfiek 73 
                      +++ a ++ g + f+ + ske  +++++g+++ p+++l  +  +e+v y+ge +++  + +f+++
     EEA21544.1 174 ALLRSLAIDFLGGINFAQIRSKEskAVEQFGITSfPTLILLPAGGSEPVVYEGE-MKKALMLEFLSQ 239
                    56677788888887777777666669999****99******************9.688888887776 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.91
                    TTHHHHHHHHHHHHHHTTTT.-EEEEEETT.GGHHHHH.HTT--GGG-SEEEEEESSSS-EEEET.TSS--HHHHHHHHH CS
  Thioredoxin_6 108 eeteklkkaiekvakefkdk.infaladak.sfkrple.ylglsssdlPvivivdsashkykypp.kdefspeklkeFlk 183
                     + +++++++++++ ++ +  + f  + a  s +++l+ +lgls+++   i+ v+ +++ +  +  +d f   +++ +++
     EEA21544.1 340 ASAKEALSTVSELSHKLTGHhLPFYSVPAInSHAKILRtELGLSETSTTEIIAVNGRRGWWRHYSsEDGFGLHSVESWID 419
                    56788888888888888886255555555555566888899999988888888887777777776677788888888875 PP

>> AhpC-TSA  AhpC/TSA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   8.4e-06     0.017      25      71 ..      45      89 ..      29      97 .. 0.87
   2 ?   -2.7   0.0       2.6   5.3e+03      81     100 ..     172     205 ..     138     214 .. 0.53

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 8.4e-06
                TSEEEEEEESTST-CCHHHHHHHHHHCHHHCCCTTEEEEEEESSSCH CS
    AhpC-TSA 25 gkpvvlffypkdwcpvCttelpalaklyeefkergvevigvsvdspe 71
                ++  ++ fy+  wc +C++  pa++k++++++ + ++v ++++d+ e
  EEA21544.1 45 NHTSIVEFYAP-WCGHCQNLKPAYEKAAKNLEGL-AKVAAINCDDDE 89
                577899*****.********************55.89******9987 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 2.6
                 H...............SSEEEE-TTSHHHHHTT- CS
    AhpC-TSA  81 s..............lnfpllsDeegkvakaygv 100
                                +nf  +  +e+k+++++g+
  EEA21544.1 172 TsallrslaidflggINFAQIRSKESKAVEQFGI 205
                 1444444445555556666666666666666665 PP

>> Thioredoxin_7  Thioredoxin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   9.9e-06      0.02      19      81 ..      47     108 ..      41     110 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 9.9e-06
                    -EEEEE--TT-HHHHHHHHHHHH-HHHHH.HHHT-EEEEESS--S-GGG.-TT---SSEEEEE CS
  Thioredoxin_7  19 pvlvffgaswcftCqalerdflsdeevkaalaekfvllrvdvterdanileldeqgvPvvafl 81 
                    + +v f a wc++Cq l+ + +++ ++ +    k++  + d++e+++  +++  qg+P++ ++
     EEA21544.1  47 TSIVEFYAPWCGHCQNLKPAYEKAAKNLE-GLAKVAAINCDDDENKPLCGQMGVQGFPTLKIV 108
                    56899*******************99999.899*************96688888999998776 PP

>> Thioredoxin_3  Thioredoxin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.1   0.00092       1.8       8      53 ..      55     105 ..      48     120 .. 0.71
   2 ?    3.1   0.0      0.05     1e+02      29      63 ..     187     226 ..     171     238 .. 0.73
   3 ?   -2.6   0.3         3   5.9e+03      29      48 ..     436     456 ..     429     461 .. 0.67

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00092
                    SSSTTCHHHHHHHHHHCHCCTCEC....EEECCTTHHHH.HHCT-SSSSEE CS
  Thioredoxin_3   8 pgCakCpklekavkeaaaekgika....evekvtdfeei.ekygVmsvPal 53 
                    p C +C++l+ a ++aa++++  a       +  +++ +  ++gV+  P+l
     EEA21544.1  55 PWCGHCQNLKPAYEKAAKNLEGLAkvaaINCDDDENKPLcGQMGVQGFPTL 105
                    67******************6555233322223455555688888888887 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.05
                    CECEEECCTTHHHHHHCT-SSSSEEECT.....TCEEEES CS
  Thioredoxin_3  29 ikaevekvtdfeeiekygVmsvPalvid.....gkvvvsG 63 
                    i++  ++ ++++ +e++g++s P+l++      + vv++G
     EEA21544.1 187 INFAQIRSKESKAVEQFGITSFPTLILLpaggsEPVVYEG 226
                    66677788999999***********874455556666666 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 3
                    CECEEECCTTHHHH.HHCT-S CS
  Thioredoxin_3  29 ikaevekvtdfeei.ekygVm 48 
                    ikae ekv++  e  ek +V+
     EEA21544.1 436 IKAEEEKVEEKAEEpEKEKVE 456
                    788888886666665777775 PP

>> TraF  F plasmid transfer operon protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   8.5e-05      0.17     126     204 ..      42     113 ..      27     117 .. 0.84
   2 ?    6.1   0.0    0.0043       8.5     164     199 ..     180     214 ..     174     228 .. 0.77
   3 ?   -1.2   2.0      0.76   1.5e+03      23      45 ..     243     265 ..     224     284 .. 0.50
   4 ?   -4.1   2.8       5.6   1.1e+04      11      26 ..     442     457 ..     429     463 .. 0.44

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 8.5e-05
        TraF 126 klakeygLlfFyrgkcpyceaqapilqafadky.gl.evraVsvdgrplpelpnarvdkgqaarlgvkrtPalvlvdpksq 204
                 + +++  ++ Fy++ c+ c+ + p +++ a++  gl +v a+++d+  ++ l           ++gv+ +P+l +v p ++
  EEA21544.1  42 NKSNHTSIVEFYAPWCGHCQNLKPAYEKAAKNLeGLaKVAAINCDDDENKPLCG---------QMGVQGFPTLKIVVPGKK 113
                 5577888999********************99865548*********8876666.........*************99975 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.0043
        TraF 164 aVsvdgrplpelpnarvdkgqaa.rlgvkrtPalvlv 199
                 a++  g+++  ++++r ++++a  ++g++++P+l+l 
  EEA21544.1 180 AIDFLGGIN--FAQIRSKESKAVeQFGITSFPTLILL 214
                 556666666..8888877777766***********97 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 0.76
        TraF  23 kaakpalkeptseesatesaael 45 
                 ++++pa++ p+++ s ++++a  
  EEA21544.1 243 PNPDPAPAVPKKKSSSPKKPASS 265
                 22222222223333333333322 PP

  == domain 4  score: -4.1 bits;  conditional E-value: 5.6
        TraF  11 ekeekkekakppkaak 26 
                 + eek+e+++++k++k
  EEA21544.1 442 KVEEKAEEPEKEKVEK 457
                 1222222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (464 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       712  (0.0397122); expected 358.6 (0.02)
Passed bias filter:                      442  (0.0246528); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.58u 0.34s 00:00:00.92 Elapsed: 00:00:00.50
# Mc/sec: 2808.63
//
Query:       EEA21545.1  [L=1063]
Description: nucleolar ATPase Kre33, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.8e-98  328.5   0.0    3.3e-98  327.6   0.0    1.5  1  GNAT_acetyltr_2  GNAT acetyltransferase 2
    1.2e-92  309.9   0.0    2.3e-92  309.0   0.0    1.5  1  tRNA_bind_2      Possible tRNA binding domain
    1.3e-64  217.3   0.0    3.9e-64  215.7   0.0    1.8  2  Helicase_RecD    Helicase
      5e-34  116.1   0.3    1.3e-33  114.8   0.0    1.9  2  DUF1726          Domain of unknown function (DUF1726)
    0.00028   20.7   0.1      0.028   14.2   0.0    2.6  2  AAA_30           AAA domain
  ------ inclusion threshold ------
      0.022   15.1   0.0      0.081   13.3   0.0    2.0  1  AAA_19           AAA domain
      0.024   14.9   0.0        0.7   10.2   0.0    2.6  2  AAA_22           AAA domain
      0.051   13.8   0.0       0.41   10.9   0.0    2.4  2  Acetyltransf_1   Acetyltransferase (GNAT) family
       0.11   12.7   0.1       0.26   11.5   0.1    1.6  1  GHMP_kinases_N   GHMP kinases N terminal domain


Domain annotation for each model (and alignments):
>> GNAT_acetyltr_2  GNAT acetyltransferase 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  327.6   0.0  1.6e-101   3.3e-98       1     226 [.     540     769 ..     540     770 .. 0.96

  Alignments for each domain:
  == domain 1  score: 327.6 bits;  conditional E-value: 1.6e-101
  GNAT_acetyltr_2   1 klvallvssHYknsPnDLqllsDaPahklfvLlapkkek.kklpevlcvvqvalEGkiskesvknslsrgkrasGdlipwtlsqqfqdeefasl 93 
                      +++al+v+sHYknsPnDLql+sDaPah+lfvL+ p +e+ +klpe+lcv+qvalEG+is+esv+nslsrg+ra Gdlipw++sqqfqde+fa l
       EEA21545.1 540 QMMALYVASHYKNSPNDLQLMSDAPAHQLFVLVPPIDEEaTKLPEPLCVIQVALEGRISRESVMNSLSRGQRAGGDLIPWLVSQQFQDEDFAGL 633
                      69*********************************99999****************************************************** PP

  GNAT_acetyltr_2  94 sGaRivRiAvhpelqkmGYGsralellekyyegklssleeeeekeeeeeeekeeeee...klsleeeklkprkelpplllklseekpekldylg 184
                      sGaR+vRiA++pe+ +mGYGsralell ++yegk+++l+e+ + ++ee  ++++++    +l  ++ ++++ +++ppl+ klse++p++ldy+g
       EEA21545.1 634 SGARVVRIATNPEYLNMGYGSRALELLVDFYEGKFANLSEDVSYASEEMVRVTDDQLenaNLLDDDVHVRDIRSMPPLFGKLSEKRPDTLDYVG 727
                      *****************************************9999998888777665555667788899999********************** PP

  GNAT_acetyltr_2 185 vsfGltseLlkFWkragfspvylrqtaneltGEhsaimlrsl 226
                      vs+Glt++L+kFWkra+fspvylrqtaneltGEhs++mlr+l
       EEA21545.1 728 VSYGLTPSLHKFWKRASFSPVYLRQTANELTGEHSCVMLRAL 769
                      ****************************************87 PP

>> tRNA_bind_2  Possible tRNA binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  309.0   0.0   1.1e-95   2.3e-92       1     235 []     778    1011 ..     778    1011 .. 0.98

  Alignments for each domain:
  == domain 1  score: 309.0 bits;  conditional E-value: 1.1e-95
                   HHHHHHHHHHHHHHHHHHHHSS------S--------------------------------HHHHHHHHHHHHS---HHHHHSSSSHHHHHHHH-- CS
  tRNA_bind_2    1 WLgafakdFrkRflsLLsyqFrkfeavlaLsilesknkgeklekseekkeltkeeldellspfDlkRLesYannllDYhvilDllptlaklyFsgr 96  
                   WL+a+++dF+kRflsLLsyqF++f +vl+Lsi+es+++g+kl++s ++++ltk  ld+ +spfDlkRL+sYann+lDYhvilD++pt+a++yF g 
   EEA21545.1  778 WLSAYTRDFHKRFLSLLSYQFKEFASVLSLSICESATAGSKLDPSFSPSRLTKPVLDAAFSPFDLKRLDSYANNMLDYHVILDMVPTIAQFYFLGS 873 
                   ************************************************************************************************ PP

                   SSTTTS-SSSSSSHHHHHHTT---HHHHHHHHT--SSHHHHHHHHHHHHHHHHH-HHHHHHHHH-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  tRNA_bind_2   97 lkeevkLsavqsaiLlaiGLQrksvddlekeLnlpsnQvlalFvkiirkvskalreilekaieeelpkekeeekaaeaeeeeakekelkpleesle 192 
                   l+ +v+Ls+vq++iLla+GLQrk+vd+lekeLnlps+Q+la+F+ki+rk+s+++r +le a++++lp++ ++ +a+ a++ ++ +++++ple+ le
   EEA21545.1  874 LQGKVNLSGVQQCILLAVGLQRKNVDELEKELNLPSSQLLAMFIKIVRKISTHFRGLLEGAVAATLPEKLNTVDASGAHD-DVIDDKFQPLETGLE 968 
                   *********************************************************************99877766665.66799********** PP

                   XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  tRNA_bind_2  193 eeLeeaakeveeklkekqrelidsldlekYaikgdeeewekae 235 
                   eeL+e+++++++++kekqr+lid+l+l+kY+i++  + we+ae
   EEA21545.1  969 EELREGGEQIDKEMKEKQRALIDALPLDKYEINNGTAGWEEAE 1011
                   ****************************************986 PP

>> Helicase_RecD  Helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       2.1   4.2e+03     118     163 ..     134     175 ..     123     190 .. 0.68
   2 !  215.7   0.0     2e-67   3.9e-64       2     177 .]     283     498 ..     282     498 .. 0.94

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 2.1
  Helicase_RecD 118 vlatTvhGYEGtGrgfslkflkqlkkekkrelreleleepiRyaeg 163
                    +la T++  EG G  + l +lk +k+  k +l  l+++ + Ry+++
     EEA21545.1 134 LLARTIETVEGGG--IVLLLLKGMKSL-K-QLYTLSMDIHSRYRTE 175
                    6788999999988..556777776643.3.6888888888888643 PP

  == domain 2  score: 215.7 bits;  conditional E-value: 2e-67
  Helicase_RecD   2 ltAdRGRGKSaalGlalaaliaegksnilvtapskenvktlfeflakglealglke..........eekkkkaekaelrvr.....kqrieyiapd 82 
                    ltA+RGRGKSaalG+a+aa++a+g+sni++t+ps+en+ktlfef++kg++ +g+ +          ++ ++ka+   +  +     +q+i+yi+p+
     EEA21545.1 283 LTAGRGRGKSAALGVAIAAAVAHGYSNIFITSPSPENLKTLFEFVFKGFDVMGYMDhvdytilqstNPAFNKAIVR-V--NihrnhRQTIQYIQPQ 375
                    9******************************************************999***999886766666632.2..233567********** PP

  Helicase_RecD  83 ellklkeqadllvvDEAAaiplpllkkllekfkrvvlatTvhGYEGtGrgfslkflkqlkke..............................kkre 148
                    ++ +l  qa+llv+DEAAaiplpl++kll +++ v++a+T++GYEGtGr++slk+++ql+++                               +r+
     EEA21545.1 376 DAYALG-QAELLVIDEAAAIPLPLVRKLL-GPYLVFMASTINGYEGTGRSLSLKLIQQLREQsrgaslkdadtdiadrstgksaknsekgiiGSRT 469
                    ****98.8*********************.**************************************************************777* PP

  Helicase_RecD 149 lreleleepiRyaegdplEkwlndlLlLd 177
                    lre++l+epiRya+gd++Ekwln++L+Ld
     EEA21545.1 470 LREVTLSEPIRYAAGDSVEKWLNKVLCLD 498
                    ****************************7 PP

>> DUF1726  Domain of unknown function (DUF1726)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.8   0.0   6.6e-37   1.3e-33       1      93 []     108     202 ..     108     202 .. 0.99
   2 ?   -4.0   0.1       7.5   1.5e+04      72      84 ..     783     795 ..     777     800 .. 0.64

  Alignments for each domain:
  == domain 1  score: 114.8 bits;  conditional E-value: 6.6e-37
     DUF1726   1 ykesekvLGqtydllvldlfealtPnalgrlvetVrGGGliilllppleelkqlyt...dfhkklvveplteevkkrfnkrfirklkehegilivd 93 
                 yke+ek+LG+ty++++l++fea+tPn+l+r++etV+GGG+++lll+ +++lkqlyt   d+h+++++e+++ +v +rfn+rfi +l +++++l+vd
  EEA21545.1 108 YKETEKILGNTYGMCILQDFEAITPNLLARTIETVEGGGIVLLLLKGMKSLKQLYTlsmDIHSRYRTEAHD-DVVARFNERFILSLGSCDSCLVVD 202
                 9*********************************************************************6.**********************98 PP

  == domain 2  score: -4.0 bits;  conditional E-value: 7.5
     DUF1726  72 kkrfnkrfirklk 84 
                 ++ f krf++ l+
  EEA21545.1 783 TRDFHKRFLSLLS 795
                 4557777766654 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.0   1.4e-05     0.028      18     109 ..     278     403 ..     258     405 .. 0.72
   2 ?    3.7   0.0     0.022        45      21      46 ..     412     438 ..     409     491 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 1.4e-05
      AAA_30  18 drvavltGpAGtGKttalkalreaweaag.grviglAptgkaAkvLae..............elgieastiakllkrlk.................... 81 
                 + +++lt++ G GK+ al+++ +a+ a+g  ++++ +p+ +  k+L e                              +                    
  EEA21545.1 278 RSTVTLTAGRGRGKSAALGVAIAAAVAHGySNIFITSPSPENLKTLFEfvfkgfdvmgymdhV---------------Dytilqstnpafnkaivrvni 361
                 345889***************888888874789999******999995444444333322220...............222222334555556666667 PP

      AAA_30  82 ..............grarlepgtllivDEagmvdtkqlaall 109
                               ++ +l +++ll++DEa+ +    +++ll
  EEA21545.1 362 hrnhrqtiqyiqpqDAYALGQAELLVIDEAAAIPLPLVRKLL 403
                 7777888899999977889999*********99888888876 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.022
      AAA_30  21 avltGpAGtGKttalkalreaweaa.g 46 
                 ++++G+ GtG + +lk ++++ e++ g
  EEA21545.1 412 STINGYEGTGRSLSLKLIQQLREQSrG 438
                 6799*****************999944 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   4.1e-05     0.081       4     122 ..     271     403 ..     269     408 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 4.1e-05
      AAA_19   4 ave.alkekvllvtaGpGtGKTrvlkhivallvelggvkpeeillvaftgrAakelrerlaalgae..........atTiHrlal.........ldfdd 82 
                 a++ ++ ++++ +taG G GK+  l  ++a +v+ g     +i + ++     k l e + +               +Ti + ++         +++++
  EEA21545.1 271 AIAeKTLRSTVTLTAGRGRGKSAALGVAIAAAVAHGY---SNIFITSPSPENLKTLFEFVFK---GfdvmgymdhvDYTILQSTNpafnkaivrVNIHR 363
                 4544788899***********************9994...6899999999999999996522...2223455566655555554466666777777777 PP

      AAA_19  83 lltealelleeaeeekklqeeellivDEfqdvd.elqyrLl 122
                    ++ ++++  ++   l ++ell++DE+  +  +l  +Ll
  EEA21545.1 364 NHRQTIQYIQP-QDAYALGQAELLVIDEAAAIPlPLVRKLL 403
                 77777888774.5667786777*******999999999988 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   0.00035       0.7       8     106 ..     281     396 ..     275     405 .. 0.75
   2 ?    1.4   0.0      0.17   3.5e+02      10      33 ..     414     437 ..     411     473 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00035
      AAA_22   8 lvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelka........................erlsseelleal 82 
                 +++t+  G GK+  l      ++++      + + +f+t ps++++k+l++ +++ +++ +                                +  ++ 
  EEA21545.1 281 VTLTAGRGRGKSAALGVAIAAAVAH------GYSNIFITSPSPENLKTLFEFVFKGFDVMGYMdhvdytilqstnpafnkaivrvniH-----RNHRQT 368
                 5678888999999998888888876......99*************************99998******9999987777777555431.....222222 PP

      AAA_22  83 eqalrarav............ielliiDEaqhlrse 106
                                       ell+iDEa  + + 
  EEA21545.1 369 I-------QyiqpqdayalgqAELLVIDEAAAI-PL 396
                 2.......133333335556679*******987.54 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.17
      AAA_22  10 vtGesGtGKTtllrrlleqldeea 33 
                 + G  GtG++++l+ +++  ++  
  EEA21545.1 414 INGYEGTGRSLSLKLIQQLREQSR 437
                 66889*********9999876654 PP

>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0      0.91   1.8e+03      30      55 ..      50      74 ..      15     116 .. 0.63
   2 ?   10.9   0.0   0.00021      0.41      62      90 ..     637     665 ..     613     680 .. 0.87

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.91
                    STTC.EEEEEEETTEEEEEEEEEEEET CS
  Acetyltransf_1 30 leae.gllvaeedgeliGfisllkipd 55
                    ++++  l+++++d  liGf s +k+ +
      EEA21545.1 50 KQNKsVLWAYKKD--LIGFSSHRKKRE 74
                    3333355555555..999988777766 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00021
                     EEEEEEESGGGTTSSHHHHHHHHHHHHHH CS
  Acetyltransf_1  62 yieslaVspeyrgkGlGsaLlealeerar 90 
                      + ++a +pey ++G+Gs+ le l+++ +
      EEA21545.1 637 RVVRIATNPEYLNMGYGSRALELLVDFYE 665
                     56789*******************99765 PP

>> GHMP_kinases_N  GHMP kinases N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.1   0.00013      0.26       7      33 ..     282     308 ..     276     330 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00013
                     SSHTTSSSCHHHHHHHHHHHHHHHHTT CS
  GHMP_kinases_N   7 eiPvgaGLGSSAAlavalvaAllallg 33 
                     ++  g+G G SAAl va++aA+++ ++
      EEA21545.1 282 TLTAGRGRGKSAALGVAIAAAVAHGYS 308
                     557799*****************9774 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1063 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       776  (0.0432818); expected 358.6 (0.02)
Passed bias filter:                      578  (0.0322383); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.79u 0.31s 00:00:01.10 Elapsed: 00:00:00.46
# Mc/sec: 6898.34
//
Query:       EEA21546.1  [L=308]
Description: endo-1,3(4)-beta-glucanase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    0.00014   21.4   0.2    0.00051   19.6   0.0    2.0  3  Glyco_hydro_16  Glycosyl hydrolases family 16


Domain annotation for each model (and alignments):
>> Glyco_hydro_16  Glycosyl hydrolases family 16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.0   2.9e-08   0.00051      22      84 ..      79     144 ..      54     167 .. 0.79
   2 ?   -2.4   0.0      0.15   2.8e+03     114     125 ..     199     210 ..     179     212 .. 0.82
   3 ?   -2.4   0.0      0.15   2.7e+03     154     168 ..     260     274 ..     248     280 .. 0.78

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 2.9e-08
                     EEEEEEEEEEEEEEECCEESSEEEEEEEE..---STTEEEEEEEETGGTSTTEEEEE.EEETT-TT CS
  Glyco_hydro_16  22 ltltldkesgsrikskksflyGkvearik..aaksaGvvtafylssedekahdEiDi.EflGndtg 84 
                     +t + + + + r++s+ +++ G +  ++   +++  G+++a+++  +++++ +EiDi E +  +t 
      EEA21546.1  79 TTASSTGRRSVRLTSTATYTRGLFVLDLArmPGSICGTWPAYWTVGSHWPDDGEIDIiEGVNLQTA 144
                     444455577899999999999*99999988889999********9888*********998844444 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.15
                     EEEEEEETTEEE CS
  Glyco_hydro_16 114 tYaieWtpdkik 125
                      Y +eWt+++i+
      EEA21546.1 199 IYVMEWTNKYIQ 210
                     588999999987 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 0.15
                     EEEEEEEBSHHHSSE CS
  Glyco_hydro_16 154 vavslwpgsdwateq 168
                     ++ + w+gs w+t++
      EEA21546.1 260 TFCGNWAGSVWSTSK 274
                     456799999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (308 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       366  (0.0204139); expected 358.6 (0.02)
Passed bias filter:                      286  (0.0159518); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.44
# Mc/sec: 2118.26
//
Query:       EEA21547.1  [L=1589]
Description: Golgi complex component (Vps8), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.7e-59  200.7   1.7    7.3e-59  198.6   0.3    2.3  2  Vps8       Golgi CORVET complex core vacuolar protein 8
    3.3e-05   23.8   1.7      0.091   12.6   0.1    3.5  3  Clathrin   Region in Clathrin and VPS
     0.0017   18.4   0.1     0.0017   18.4   0.1    2.3  2  zf-C3H2C3  Zinc-finger
     0.0059   16.3   0.0      0.011   15.3   0.0    1.4  1  Pox_D3     Chordopoxvirinae D3 protein


Domain annotation for each model (and alignments):
>> Vps8  Golgi CORVET complex core vacuolar protein 8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  198.6   0.3   1.6e-62   7.3e-59       1     198 []     709     892 ..     709     892 .. 0.95
   2 ?    0.6   0.0     0.075   3.3e+02     163     185 ..    1096    1122 ..    1004    1188 .. 0.71

  Alignments for each domain:
  == domain 1  score: 198.6 bits;  conditional E-value: 1.6e-62
        Vps8   1 vFlevLepyilsgklkslppevvkalvehysskgelerleelilhldpksLDldqvlklckehrLydaliYvwnkaldDYvtPlvellklirsaeeeee 99 
                 +Fl+vLep+i ++k++s+pp+++kal++hys + + +rlee+i+ ldp+++D++qv++lck+h+Lyda+iYvwn++l DY+ Pl+ell+ ++++  +++
  EEA21547.1 709 IFLDVLEPFIRDNKVRSMPPTALKALINHYSATYTSTRLEEVICLLDPTTMDIEQVTTLCKQHNLYDAFIYVWNHVLLDYIGPLEELLAFATRV-MDST 806
                 7****************************************************************************************99995.4567 PP

        Vps8 100 ekeeeeeeeeeaykvfeYlsyiLtGraYPsgeeleeeeaskakseiyslLfsgksiewpkgsgklltkeeseeepafPylrlLLkfdaeeflsvLneaF 198
                 +++  + e e+a kvf+Yls+i+tGr+YP+gee+++++a +ak+++y++Lf g++                +++++f  lr+ Lkfd+++f+s+LneaF
  EEA21547.1 807 DSSVASIEYENAIKVFPYLSFIFTGRTYPTGEEMSDDQAVNAKQTLYTYLFTGTH-------------LPGSKQKPFGALRAVLKFDSSSFMSMLNEAF 892
                 888999999******************************************9983.............34567788**********************9 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.075
        Vps8  163 k....lltkeeseeepafPylrlLLkf 185 
                  +    +l++ ++++ +++ yl++LL+ 
  EEA21547.1 1096 SlhavFLKSLDQDDYRQYHYLSTLLEP 1122
                  134456666677777777777777763 PP

>> Clathrin  Region in Clathrin and VPS
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.1     2e-05     0.091      42      95 ..     729     783 ..     695     789 .. 0.80
   2 ?    1.7   0.1     0.049   2.2e+02      66     109 ..     995    1038 ..     983    1053 .. 0.75
   3 !    6.2   0.0    0.0019       8.6      42     110 ..    1138    1208 ..    1111    1218 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 2e-05
                 HHHHHHHHHHHHHTT-HHHHHHTTS..S---S-TTHHHHHHHT-SSHHHHHHHHHT CS
    Clathrin  42 palqtallelyakyddpqeleeflk..knnnydlekvaklcekadlyeeavilykk 95 
                 +al  +++   a+y+  ++lee++     +++d+e+v  lc++++ly+  ++++++
  EEA21547.1 729 TALKALINHYSATYTS-TRLEEVICllDPTTMDIEQVTTLCKQHNLYDAFIYVWNH 783
                 5666666777788886.9*****99667777*********************9976 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.049
                  SS---S-TTHHHHHHHT-SSHHHHHHHHHTTXTHSSHSSXSSSS CS
    Clathrin   66 kknnnydlekvaklcekadlyeeavilykkinefkkaisllkkl 109 
                  ++++  dl++++ l ++a++y+ ++  y++ ++++++i+++ ++
  EEA21547.1  995 STYHPPDLQSLIPLFKEAGYYRVLKSTYRAEKQYAELIVTYLED 1038
                  44444788888888888888888888888888888888875554 PP

  == domain 3  score: 6.2 bits;  conditional E-value: 0.0019
                  HHHHHHHHHHHHHTT-HHHHHHTTS..S---S-TTHHHHHHHT-SSHHHHHHHHHTTXTHSSHSS.XSSSSH CS
    Clathrin   42 palqtallelyakyddpqeleeflk..knnnydlekvaklcekadlyeeavilykkinefkkais.llkklk 110 
                  +++ +++++l+++y++ + + ++++  + n+  l++v+   e  + ++ av+l+ + +++ ka++ ll +l+
  EEA21547.1 1138 RSMVELYVQLLCRYNR-SHVADYVDtlRVNELRLDEVLPAMEGSGVVDAAVVLLARQGQVRKAMDrLLAYLN 1208
                  67788999*******8.********666677*********************************97566665 PP

>> zf-C3H2C3  Zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.7      0.47   2.1e+03      18      24 ..     534     540 ..     533     543 .. 0.90
   2 !   18.4   0.1   3.7e-07    0.0017      11      29 ..    1539    1558 ..    1534    1559 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.47
   zf-C3H2C3  18 kHlvHak 24 
                 kH++H++
  EEA21547.1 534 KHIYHTD 540
                 8****97 PP

  == domain 2  score: 18.4 bits;  conditional E-value: 3.7e-07
   zf-C3H2C3   11 pfvaysCkHlvHakC.adee 29  
                  p+v + C+Hl+H+ C ++++
  EEA21547.1 1539 PVVVFACRHLYHRSClVTKT 1558
                  9**************99876 PP

>> Pox_D3  Chordopoxvirinae D3 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   2.5e-06     0.011     164     223 ..     722     782 ..     705     788 .. 0.88

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 2.5e-06
      Pox_D3 164 lifkaesskLkellekll.seskldkakviaivklkdaddikLvkfcYdrdkFraFvyaWf 223
                  ++ + +  Lk+l+++   + ++++  +vi+++    +d  ++++ c + + + aF+y W 
  EEA21547.1 722 KVRSMPPTALKALINHYSaTYTSTRLEEVICLLDPTTMDIEQVTTLCKQHNLYDAFIYVWN 782
                 57888899*********97777788889******9999999*******************5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1589 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       645  (0.0359752); expected 358.6 (0.02)
Passed bias filter:                      527  (0.0293937); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.97u 0.28s 00:00:01.25 Elapsed: 00:00:00.47
# Mc/sec: 10230.00
//
Query:       EEA21548.1  [L=1589]
Description: Golgi complex component (Vps8), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.7e-59  200.7   1.7    7.3e-59  198.6   0.3    2.3  2  Vps8       Golgi CORVET complex core vacuolar protein 8
    3.3e-05   23.8   1.7      0.091   12.6   0.1    3.5  3  Clathrin   Region in Clathrin and VPS
     0.0017   18.4   0.1     0.0017   18.4   0.1    2.3  2  zf-C3H2C3  Zinc-finger
     0.0059   16.3   0.0      0.011   15.3   0.0    1.4  1  Pox_D3     Chordopoxvirinae D3 protein


Domain annotation for each model (and alignments):
>> Vps8  Golgi CORVET complex core vacuolar protein 8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  198.6   0.3   1.6e-62   7.3e-59       1     198 []     709     892 ..     709     892 .. 0.95
   2 ?    0.6   0.0     0.075   3.3e+02     163     185 ..    1096    1122 ..    1004    1188 .. 0.71

  Alignments for each domain:
  == domain 1  score: 198.6 bits;  conditional E-value: 1.6e-62
        Vps8   1 vFlevLepyilsgklkslppevvkalvehysskgelerleelilhldpksLDldqvlklckehrLydaliYvwnkaldDYvtPlvellklirsaeeeee 99 
                 +Fl+vLep+i ++k++s+pp+++kal++hys + + +rlee+i+ ldp+++D++qv++lck+h+Lyda+iYvwn++l DY+ Pl+ell+ ++++  +++
  EEA21548.1 709 IFLDVLEPFIRDNKVRSMPPTALKALINHYSATYTSTRLEEVICLLDPTTMDIEQVTTLCKQHNLYDAFIYVWNHVLLDYIGPLEELLAFATRV-MDST 806
                 7****************************************************************************************99995.4567 PP

        Vps8 100 ekeeeeeeeeeaykvfeYlsyiLtGraYPsgeeleeeeaskakseiyslLfsgksiewpkgsgklltkeeseeepafPylrlLLkfdaeeflsvLneaF 198
                 +++  + e e+a kvf+Yls+i+tGr+YP+gee+++++a +ak+++y++Lf g++                +++++f  lr+ Lkfd+++f+s+LneaF
  EEA21548.1 807 DSSVASIEYENAIKVFPYLSFIFTGRTYPTGEEMSDDQAVNAKQTLYTYLFTGTH-------------LPGSKQKPFGALRAVLKFDSSSFMSMLNEAF 892
                 888999999******************************************9983.............34567788**********************9 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.075
        Vps8  163 k....lltkeeseeepafPylrlLLkf 185 
                  +    +l++ ++++ +++ yl++LL+ 
  EEA21548.1 1096 SlhavFLKSLDQDDYRQYHYLSTLLEP 1122
                  134456666677777777777777763 PP

>> Clathrin  Region in Clathrin and VPS
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.1     2e-05     0.091      42      95 ..     729     783 ..     695     789 .. 0.80
   2 ?    1.7   0.1     0.049   2.2e+02      66     109 ..     995    1038 ..     983    1053 .. 0.75
   3 !    6.2   0.0    0.0019       8.6      42     110 ..    1138    1208 ..    1111    1218 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 2e-05
                 HHHHHHHHHHHHHTT-HHHHHHTTS..S---S-TTHHHHHHHT-SSHHHHHHHHHT CS
    Clathrin  42 palqtallelyakyddpqeleeflk..knnnydlekvaklcekadlyeeavilykk 95 
                 +al  +++   a+y+  ++lee++     +++d+e+v  lc++++ly+  ++++++
  EEA21548.1 729 TALKALINHYSATYTS-TRLEEVICllDPTTMDIEQVTTLCKQHNLYDAFIYVWNH 783
                 5666666777788886.9*****99667777*********************9976 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.049
                  SS---S-TTHHHHHHHT-SSHHHHHHHHHTTXTHSSHSSXSSSS CS
    Clathrin   66 kknnnydlekvaklcekadlyeeavilykkinefkkaisllkkl 109 
                  ++++  dl++++ l ++a++y+ ++  y++ ++++++i+++ ++
  EEA21548.1  995 STYHPPDLQSLIPLFKEAGYYRVLKSTYRAEKQYAELIVTYLED 1038
                  44444788888888888888888888888888888888875554 PP

  == domain 3  score: 6.2 bits;  conditional E-value: 0.0019
                  HHHHHHHHHHHHHTT-HHHHHHTTS..S---S-TTHHHHHHHT-SSHHHHHHHHHTTXTHSSHSS.XSSSSH CS
    Clathrin   42 palqtallelyakyddpqeleeflk..knnnydlekvaklcekadlyeeavilykkinefkkais.llkklk 110 
                  +++ +++++l+++y++ + + ++++  + n+  l++v+   e  + ++ av+l+ + +++ ka++ ll +l+
  EEA21548.1 1138 RSMVELYVQLLCRYNR-SHVADYVDtlRVNELRLDEVLPAMEGSGVVDAAVVLLARQGQVRKAMDrLLAYLN 1208
                  67788999*******8.********666677*********************************97566665 PP

>> zf-C3H2C3  Zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.7      0.47   2.1e+03      18      24 ..     534     540 ..     533     543 .. 0.90
   2 !   18.4   0.1   3.7e-07    0.0017      11      29 ..    1539    1558 ..    1534    1559 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.47
   zf-C3H2C3  18 kHlvHak 24 
                 kH++H++
  EEA21548.1 534 KHIYHTD 540
                 8****97 PP

  == domain 2  score: 18.4 bits;  conditional E-value: 3.7e-07
   zf-C3H2C3   11 pfvaysCkHlvHakC.adee 29  
                  p+v + C+Hl+H+ C ++++
  EEA21548.1 1539 PVVVFACRHLYHRSClVTKT 1558
                  9**************99876 PP

>> Pox_D3  Chordopoxvirinae D3 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   2.5e-06     0.011     164     223 ..     722     782 ..     705     788 .. 0.88

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 2.5e-06
      Pox_D3 164 lifkaesskLkellekll.seskldkakviaivklkdaddikLvkfcYdrdkFraFvyaWf 223
                  ++ + +  Lk+l+++   + ++++  +vi+++    +d  ++++ c + + + aF+y W 
  EEA21548.1 722 KVRSMPPTALKALINHYSaTYTSTRLEEVICLLDPTTMDIEQVTTLCKQHNLYDAFIYVWN 782
                 57888899*********97777788889******9999999*******************5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1589 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       645  (0.0359752); expected 358.6 (0.02)
Passed bias filter:                      527  (0.0293937); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.92u 0.28s 00:00:01.20 Elapsed: 00:00:00.46
# Mc/sec: 10472.02
//
Query:       EEA21549.1  [L=298]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (298 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       394  (0.0219756); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2255.74
//
Query:       EEA21550.1  [L=943]
Description: DNA-directed DNA polymerase theta, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      5e-18   65.5   0.0    1.3e-17   64.1   0.0    1.7  1  DEAD        DEAD/DEAH box helicase
    1.1e-08   35.2   0.0    2.4e-08   34.2   0.0    1.5  1  ResIII      Type III restriction enzyme, res subunit
      3e-08   34.0   0.1    3.2e-07   30.7   0.0    2.6  3  Helicase_C  Helicase conserved C-terminal domain
  ------ inclusion threshold ------
      0.022   15.0   0.0      0.094   13.0   0.0    2.0  1  AAA_22      AAA domain
      0.043   14.2   0.1        0.3   11.4   0.1    2.2  2  AAA_19      AAA domain


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.1   0.0   3.6e-21   1.3e-17      13     170 ..     169     336 ..     155     341 .. 0.84

  Alignments for each domain:
  == domain 1  score: 64.1 bits;  conditional E-value: 3.6e-21
                 TTCEEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTST...................SEEEEEETTSSHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...................xxxxxxxxxxxxxxxxx RF
        DEAD  13 gggdvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyid...................lrvlliiggvaardqls 92 
                  ++++l  a+TG GK+l++ + +l++v++   +++ ka++v P  +L+++ l+ l+++ + ++                   +rv  ++gg++ r  ++
  EEA21550.1 169 AEKNLLYTAPTGGGKSLVADVLMLRRVID---NPHRKAILVLPYVALVQEKLKWLRRIVQGVEknidtsasmkqpwkqpskeIRVTGFFGGSKSRATWA 264
                 5789***********************86...9999***********************9544444466677777777777788888888888877776 PP

                 HHHTTCSEEEEEHHHHHHHH..HCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBS CS
                 xxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  93 kldngvdivvgtpgrlddll..stgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlp 170
                 +     di + t ++   l+    ++ n++++ ++V+DE+++l d++++  ++ ++++l       +++ q+i +SATl+
  EEA21550.1 265 DT----DIAICTIEKANALVntAIEECNIDDLAVVVVDEIHMLDDDSRGYLLELMVTKLLLL----QQDIQIIGMSATLS 336
                 66....**************55456799*******************************433....34566********8 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.2   0.0   6.6e-12   2.4e-08      22     169 ..     168     335 ..     140     337 .. 0.79

  Alignments for each domain:
  == domain 1  score: 34.2 bits;  conditional E-value: 6.6e-12
                 .TTSEEEEEESTTSTHHHHH.HHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG..........GEEEESSS-B--................. CS
      ResIII  22 krdkrglikmaTGtGKTlva.aklierllkkgkeekflflvprkslleqtleefkkflseayke......igkkvsgdkkka..........kekdstn 103
                 + +k++l  ++TG GK+lva + + +r+  + + +k++++ p  +l++  l+ ++++ +   k+       ++ +++ +k++          ++    +
  EEA21550.1 168 TAEKNLLYTAPTGGGKSLVAdVLMLRRVIDNPH-RKAILVLPYVALVQEKLKWLRRIVQGVEKNidtsasMKQPWKQPSKEIrvtgffggskSRATWAD 265
                 467899999***********6666667777655.69999999999999888777777776666544444333336666666678899988877778899 PP

                 -SEEEEEHHHHHHTH........HHHTTT-SEEEEETGGGTTS.T.......TTHHHHHT---SEEEEEESS- CS
      ResIII 104 kkilvttiqsldadseeeeeeseellrdrfdviiiDEaHrlgakk.......swreilekfkeavllglTATp 169
                 ++i + ti++++a     + + ee   d   v+++DE H l +++        ++++l   ++  ++g++AT+
  EEA21550.1 266 TDIAICTIEKANALV---NTAIEECNIDDLAVVVVDEIHMLDDDSrgyllelMVTKLLLLQQDIQIIGMSATL 335
                 ***************...8899999999999************84666666788888888899*********7 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.44   1.6e+03       2      52 ..     275     337 ..     274     353 .. 0.75
   2 ?   -3.6   0.0       3.8   1.4e+04      16      35 ..     427     447 ..     417     461 .. 0.74
   3 !   30.7   0.0     9e-11   3.2e-07      43     111 .]     491     563 ..     478     563 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.44
                 HHHHHHHH.HHHTTTTSEEEEEESSHHHHHH...........HHHHHHHTTSTEEEESTTSTH CS
  Helicase_C   2 kleallel.lkleeeggkilifvntidrlek...........vklllekkgikvavlhgelpq 52 
                 k +al++  +++ ++++ ++++v  i +l++           +klll +++i+++ + ++l++
  EEA21550.1 275 KANALVNTaIEECNIDDLAVVVVDEIHMLDDdsrgyllelmvTKLLLLQQDIQIIGMSATLSN 337
                 556666663477788999999999999998788777766677777777888888877776665 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 3.8
                 TSEEEEEESSHHHHHH.HHHH CS
  Helicase_C  16 ggkilifvntidrlek.vkll 35 
                 g  +l+f+ ++  +++ ++l+
  EEA21550.1 427 GFGALVFCGSRHACQMnAQLI 447
                 556899999999987665555 PP

  == domain 3  score: 30.7 bits;  conditional E-value: 9e-11
                 EEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSS..SS...HHHHHHHHTTSSSTT CS
  Helicase_C  43 vavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlp..rn...vtsyiqriGRtgRag 111
                 va +h+ l+++ere + e++ +g+++v++at  ++ G+++p ++ Vi+ ++   r+   ++ + q++GR+gR g
  EEA21550.1 491 VAFHHAGLTTEERELVAEAYDRGTIKVIVATCSLAAGVNLP-ARRVIMQGARmgRDivgPALLRQMRGRAGRKG 563
                 678999**********************************9.777777777756444448************76 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   2.6e-05     0.094       7     124 ..     172     327 ..     168     339 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 2.6e-05
      AAA_22   7 ilvvtGesGtGKTtllrrlleqldeeakaeeerpevv..fvtlpsst..sskdllrellralglelka............................... 70 
                  l+ t+++G GK++++  l+ + ++++ +  +++ +v  +v l +++   ++ + + + ++++ +++                                
  EEA21550.1 172 NLLYTAPTGGGKSLVADVLMLRRVIDNPH--RKAILVlpYVALVQEKlkWLRRIVQGVEKNIDTSASMkqpwkqpskeirvtgffggsksratwadtdi 268
                 567799***************99654333..44444455555555555344555666666666666659999999999999999999999999988888 PP

      AAA_22  71 ...erlsseellealeqalraravielliiDEaqhlr..s.....eealeeLrsllnlsrkgvq 124
                       +  +l+++  + ++  +  +++++DE++ l+  s     e ++++L  ll   ++++q
  EEA21550.1 269 aicTIEKANALVNTAIEECNIDDL-AVVVVDEIHMLDddSrgyllELMVTKL--LLL--QQDIQ 327
                 776556666677777777777777.***********8764434433333333..333..44444 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1   8.5e-05       0.3      10     126 ..     170     316 ..     165     330 .. 0.68
   2 ?   -0.5   0.0       0.4   1.4e+03      68      78 ..     799     849 ..     753     933 .. 0.68

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 8.5e-05
      AAA_19  10 ekvllvtaGpGtGKTrvlkhiv.allvelggvkpeeill...vaftgrAakelrerlaalgaeatTiHrlal........................... 77 
                 ek+ll ta+ G GK+ v    + + ++++ ++  + il+   va+ +   k lr  +++++++++T  ++                             
  EEA21550.1 170 EKNLLYTAPTGGGKSLVADVLMlRRVIDNPHR--KAILVlpyVALVQEKLKWLRRIVQGVEKNIDTSASMKQpwkqpskeirvtgffggsksratwadt 266
                 67888899999999988766541334444433..34443122677777777788888888888888888766999999999999999999999888775 PP

      AAA_19  78 ....ldfddlltealelleeaeeekklqeeellivDEfqdvd.elqyrLlkall 126
                         ++ ++a +l++ a ee ++ + ++++vDE+ ++d +    Ll+ ++
  EEA21550.1 267 diaiC---TI-EKANALVNTAIEECNIDDLAVVVVDEIHMLDdDSRGYLLELMV 316
                 53321...22.23344445555667785666***********888888887776 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.4
      AAA_19  68 e............atTiHrlal............................l 78 
                 +            a+T+H++a                              
  EEA21550.1 799 SrynvprgvvqtlAQTCHGFAAgmvkfcqrmgwgmlavvlehmrdrlqagA 849
                 045555666666699999998777777777666666666655555555440 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (943 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       664  (0.037035); expected 358.6 (0.02)
Passed bias filter:                      463  (0.0258241); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.74u 0.28s 00:00:01.02 Elapsed: 00:00:00.46
# Mc/sec: 6163.77
//
Query:       EEA21551.1  [L=1749]
Description: PHD finger and BAH domain protein (Snt2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-20   73.3   0.3    1.6e-20   73.3   0.3    4.2  3  zf-HC5HC2H_2     PHD-zinc-finger like domain
    3.4e-18   65.7   0.9    3.4e-18   65.7   0.9    4.9  5  zf-HC5HC2H       PHD-like zinc-binding domain
    7.8e-18   64.5   0.0    1.6e-17   63.5   0.0    1.6  1  BAH              BAH domain
    6.4e-09   35.6  23.3      4e-06   26.6   5.6    5.7  6  PHD              PHD-finger
    5.2e-07   29.1   8.0    5.2e-07   29.1   8.0    5.1  5  PHD_2            PHD-finger
  ------ inclusion threshold ------
      0.057   13.6   0.2       0.14   12.4   0.2    1.6  1  Myb_DNA-binding  Myb-like DNA-binding domain
        3.7    7.3  15.1       0.15   11.7   0.9    4.0  3  GATA             GATA zinc finger


Domain annotation for each model (and alignments):
>> zf-HC5HC2H_2  PHD-zinc-finger like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   4.0     0.045   1.1e+02      55      87 ..     441     473 ..     413     494 .. 0.65
   2 ?    2.1   1.3     0.084   2.1e+02      56      84 ..    1033    1062 ..    1023    1067 .. 0.84
   3 !   73.3   0.3   6.1e-24   1.6e-20      13      95 ..    1156    1239 ..    1151    1258 .. 0.93

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.045
  zf-HC5HC2H_2  55 kekCllCkkr..kGaciqCskkeCktafHvtCala 87 
                    ++C+ C     +  ++ C+   C++++H++C + 
    EEA21551.1 441 VKTCVKCALYaaSVDSVDCAV--CHNTYHMNCVRP 473
                   456777765533444566666..888888888654 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.084
  zf-HC5HC2H_2   56 ekCllCkkr..kG.aciqCskkeCktafHvtC 84  
                    + C++C+k   +G ++++C +  C+ + H  C
    EEA21551.1 1033 LPCAVCRKPdpTGeTSVTCRD--CRLTVHQGC 1062
                    67******9885637899999..******999 PP

  == domain 3  score: 73.3 bits;  conditional E-value: 6.1e-24
  zf-HC5HC2H_2   13 lkktsderwvHvlCallvpevsfsnvaerepvd.vekikkerlkekCllCkkrkGaciqCskkeCktafHvtCalaaglvmele 95  
                    lk+t  ++wvHv Ca++ pe++f + +e ep++ +  i++er++e+C +Ck+++Gac+ C++ +C+ + Hv Cal+ag+++ ++
    EEA21551.1 1156 LKRTVGNNWVHVNCAIWHPEIKFGKAEELEPAEgFGLIPRERYRETCKVCKTTAGACLSCHYPNCNVKVHVGCALQAGYTFGFD 1239
                    8999**************************************************************************998766 PP

>> zf-HC5HC2H  PHD-like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   7.9      0.79     2e+03      35      67 ..     440     472 ..     421     491 .. 0.77
   2 ?   -2.9   0.0       3.4   8.6e+03      28      45 ..     856     873 ..     846     876 .. 0.75
   3 ?    3.6   2.0     0.031        80      33      66 ..    1029    1063 ..    1011    1084 .. 0.85
   4 !   65.7   0.9   1.3e-21   3.4e-18       1      89 [.    1166    1272 ..    1166    1273 .. 0.84
   5 ?   -3.0   0.2       3.5   9.1e+03      34      45 ..    1376    1387 ..    1364    1389 .. 0.72

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.79
  zf-HC5HC2H  35 kklkCylCkkk..vGaciqCskkkCkkafHvtCak 67 
                   ++C+ C        ++ C+   C++++H+ C +
  EEA21551.1 440 AVKTCVKCALYaaSVDSVDCAV--CHNTYHMNCVR 472
                 5578999995511345778888..*********87 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 3.4
  zf-HC5HC2H  28 ekikkerkklkCylCkkk 45 
                 ek++ +++  +C++C ++
  EEA21551.1 856 EKASDKKRGFQCKFCLTR 873
                 56677788889*999776 PP

  == domain 3  score: 3.6 bits;  conditional E-value: 0.031
  zf-HC5HC2H   33 erkklkCylCkkk..vG.aciqCskkkCkkafHvtCa 66  
                  ++k l C +C+k   +G  +++C+   C+ + H  C 
  EEA21551.1 1029 RAKVLPCAVCRKPdpTGeTSVTCRD--CRLTVHQGCY 1063
                  667789*****87775537899988..********95 PP

  == domain 4  score: 65.7 bits;  conditional E-value: 1.3e-21
  zf-HC5HC2H    1 HvvCalwipevvfeeekeiemeeiedvekikkerkklkCylCkkkvGaciqCskkkCkkafHvtCakeagllleee........eeke......... 80  
                  Hv+Ca+w pe++f +++e   e++e++  i++er + +C++Ck++ Gac++C+ ++C+ + Hv Ca +ag+++ ++        +  +         
  EEA21551.1 1166 HVNCAIWHPEIKFGKAEE--LEPAEGFGLIPRERYRETCKVCKTTAGACLSCHYPNCNVKVHVGCALQAGYTFGFDvtpvkgsrR--Dstitmkmgg 1258
                  9************99998..8****************************************************998666655441..1444555555 PP

  zf-HC5HC2H   81 .....klksyCkkH 89  
                       + +++C++H
  EEA21551.1 1259 engsvSPSIWCPNH 1272
                  55555777777777 PP

  == domain 5  score: -3.0 bits;  conditional E-value: 3.5
  zf-HC5HC2H   34 rkklkCylCkkk 45  
                  ++++ C++C+++
  EEA21551.1 1376 SEHKICIYCRTS 1387
                  456677777765 PP

>> BAH  BAH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.5   0.0   6.2e-21   1.6e-17       2     114 ..     287     396 ..     286     405 .. 0.93

  Alignments for each domain:
  == domain 1  score: 63.5 bits;  conditional E-value: 6.2e-21
                 EEETTGEEEEEETTSTTEEEEEEEEEEEEETTST.CEEEEEEEEEEECGGGSTTTTHCCCTTEEEEEEEEEEEEGGGEEEEEEEEEHHHHCTECCHCHH CS
         BAH   2 tyavGdfVyfddtstdepyqirrIeeLkenakne.eaeatvlvdwflrpeetksalklrqkrElfltrqseilplaairgkcrVvllsdleeaqnylpk 99 
                 t++v+d Vy+  +   epy+ +rI e+  ++ n     ++v+v+w++rp+++  ++++ ++r +f++ +s+ +pl++ rgkc++ + s++e++++y + 
  EEA21551.1 287 TLEVNDHVYLICEPPGEPYYLGRIMEFLPSKGNPtGPVEMVRVNWYYRPKDI--QRRVPDPRLVFASMHSDPCPLSSLRGKCTIKHVSEIENLDEYRK- 382
                 899************************888888876789*************..9999999************************************8. PP

                 CSTTEEEEEEEEETT CS
         BAH 100 klddtFycslvydpt 114
                  l d F ++ ++d++
  EEA21551.1 383 -LRDCFWYDKMFDRY 396
                 .*****999999875 PP

>> PHD  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.6   5.6   1.6e-09     4e-06       2      51 ..     444     492 ..     443     493 .. 0.91
   2 ?    1.3   0.1      0.12   3.2e+02      34      50 ..     855     871 ..     851     873 .. 0.76
   3 !   24.8   9.7   5.7e-09   1.5e-05       2      51 ..    1035    1081 ..    1034    1082 .. 0.88
   4 ?   -2.1   0.2       1.5   3.9e+03      22      30 ..    1162    1170 ..    1162    1175 .. 0.83
   5 ?    2.6   7.7     0.049   1.2e+02       2      30 ..    1202    1229 ..    1201    1232 .. 0.91
   6 ?   -1.4   0.1      0.88   2.3e+03      40      50 ..    1436    1446 ..    1426    1448 .. 0.70

  Alignments for each domain:
  == domain 1  score: 26.6 bits;  conditional E-value: 1.6e-09
                 BTTTTSTTSTTSCEEEETTTSCEEETTTSSSTHSHHSHHSSTBSSTTTHT CS
         PHD   2 CavCkkksdeeeelvqCdgCkrwfHqkClkppleseekpegewlCekCke 51 
                 C  C     ++ + v C  C++++H++C++p+l++++     w C  C++
  EEA21551.1 444 CVKCAL-YAASVDSVDCAVCHNTYHMNCVRPKLTKKPARGFAWACALCSR 492
                 999999.8999***********************8888777*******86 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.12
                 HSHHSHHSSTBSSTTTH CS
         PHD  34 leseekpegewlCekCk 50 
                  e+++++++ ++C+ C 
  EEA21551.1 855 NEKASDKKRGFQCKFCL 871
                 5566777779******6 PP

  == domain 3  score: 24.8 bits;  conditional E-value: 5.7e-09
                  BTTTTSTTSTTSCEEEETTTSCEEETTTSSSTHSHHSHHSSTBSSTTTHT CS
         PHD    2 CavCkkksdeeeelvqCdgCkrwfHqkClkppleseekpegewlCekCke 51  
                  CavC+k + ++e+ v C +C+ ++Hq C+++  +s      +wlC+ C++
  EEA21551.1 1035 CAVCRKPDPTGETSVTCRDCRLTVHQGCYGVGPDSCH---AKWLCDMCSN 1081
                  ******77779*********************99443...37******87 PP

  == domain 4  score: -2.1 bits;  conditional E-value: 1.5
                  SCEEETTTS CS
         PHD   22 krwfHqkCl 30  
                  ++w+H++C 
  EEA21551.1 1162 NNWVHVNCA 1170
                  58******6 PP

  == domain 5  score: 2.6 bits;  conditional E-value: 0.049
                  BTTTTSTTSTTSCEEEET..TTSCEEETTTS CS
         PHD    2 CavCkkksdeeeelvqCd..gCkrwfHqkCl 30  
                  C+vCk    + +  ++C+  +C+  +H+ C 
  EEA21551.1 1202 CKVCKT---TAGACLSCHypNCNVKVHVGCA 1229
                  ******...79******8778*********5 PP

  == domain 6  score: -1.4 bits;  conditional E-value: 0.88
                  HSSTBSSTTTH CS
         PHD   40 pegewlCekCk 50  
                  +e+ + C kC+
  EEA21551.1 1436 SEQAYECHKCH 1446
                  44578888886 PP

>> PHD_2  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.8   0.6         7   1.8e+04      32      35 ..     444     447 ..     443     448 .. 0.49
   2 ?    2.9   3.4     0.032        82       5      35 ..     457     490 ..     456     491 .. 0.84
   3 !   29.1   8.0     2e-10   5.2e-07       5      35 ..    1049    1079 ..    1046    1080 .. 0.96
   4 ?    1.5   4.4     0.084   2.2e+02       5      18 ..    1213    1228 ..    1209    1230 .. 0.87
   5 ?   -1.7   0.2      0.87   2.2e+03      21      35 ..    1433    1445 ..    1431    1446 .. 0.64

  Alignments for each domain:
  == domain 1  score: -4.8 bits;  conditional E-value: 7
       PHD_2  32 CrrC 35 
                 C +C
  EEA21551.1 444 CVKC 447
                 5555 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.032
       PHD_2   5 lsCdkCsvaVHasCYGvskesdgee...WlCrrC 35 
                 + C+ C    H++C + +  ++ +    W C+ C
  EEA21551.1 457 VDCAVCHNTYHMNCVRPKLTKKPARgfaWACALC 490
                 5699**********98777777666789****** PP

  == domain 3  score: 29.1 bits;  conditional E-value: 2e-10
       PHD_2    5 lsCdkCsvaVHasCYGvskesdgeeWlCrrC 35  
                  ++C  C++ VH+ CYGv ++s +++WlC+ C
  EEA21551.1 1049 VTCRDCRLTVHQGCYGVGPDSCHAKWLCDMC 1079
                  89***************************** PP

  == domain 4  score: 1.5 bits;  conditional E-value: 0.084
       PHD_2    5 lsCd..kCsvaVHasC 18  
                  lsC   +C+v VH  C
  EEA21551.1 1213 LSCHypNCNVKVHVGC 1228
                  899999*******999 PP

  == domain 5  score: -1.7 bits;  conditional E-value: 0.87
       PHD_2   21 vskesdgeeWlCrrC 35  
                    ++++   + C +C
  EEA21551.1 1433 NGQSEQ--AYECHKC 1445
                  444444..499***9 PP

>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.2   5.4e-05      0.14       5      46 .]     769     810 ..     766     810 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 5.4e-05
                      BHHHHHHHHHHHHHHTTCHHHHHHHHTSS-HHHHHHHHHHHT CS
  Myb_DNA-binding   5 teeEdelLleavkkhGnrWkkIaerlggRtekqcrsrwrnyl 46 
                      ++e   l++e+v k+G+ W  I +++g+    ++  ++++++
       EEA21551.1 769 SKEQKALFAEGVSKYGSEWINIRRHIGNIEHRHVVRYYYMWK 810
                      7889999*********************99999999999986 PP

>> GATA  GATA zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.9   5.8e-05      0.15       1      16 [.     867     882 ..     867     885 .. 0.94
   2 ?    4.2   0.3     0.013        32      21      33 ..     908     920 ..     901     922 .. 0.84
   3 ?   -3.6   2.0       3.6   9.2e+03       1      12 [.    1381    1392 ..    1381    1400 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 5.8e-05
        GATA   1 CsnCgttkTplWRrgp 16 
                 C  C t+++p+WRr+p
  EEA21551.1 867 CKFCLTRTSPQWRRAP 882
                 999***********98 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.013
        GATA  21 sLCnaCGlyykkk 33 
                  LC  C l ++k+
  EEA21551.1 908 ALCHRCALLWRKY 920
                 6***********9 PP

  == domain 3  score: -3.6 bits;  conditional E-value: 3.6
        GATA    1 CsnCgttkTplW 12  
                  C  C+t+ +p W
  EEA21551.1 1381 CIYCRTSCSPRW 1392
                  667********* PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1749 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1218  (0.0679346); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                        28  (0.00156172); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 1.33u 0.36s 00:00:01.69 Elapsed: 00:00:00.54
# Mc/sec: 9673.26
//
Query:       EEA21552.1  [L=919]
Description: high affinity cAMP phosphodiesterase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-70  237.2   0.0    3.8e-70  236.3   0.0    1.4  1  PDEase_I  3'5'-cyclic nucleotide phosphodiesterase


Domain annotation for each model (and alignments):
>> PDEase_I  3'5'-cyclic nucleotide phosphodiesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  236.3   0.0   2.1e-74   3.8e-70       1     237 [.     361     618 ..     361     619 .. 0.95

  Alignments for each domain:
  == domain 1  score: 236.3 bits;  conditional E-value: 2.1e-74
                 SSSHHHHHHHHHHHHHHHHCCHCCCC..................S-HHHHHHHHHHHHHTTTT--S--HHHHHHCT-HHHHHCCCSSHHHHHHHHHHHH CS
    PDEase_I   1 YHNfrHAadVlqalfyllkkeklkee..................ltpleilalliaalcHDvdHpGtnNsFlvnskselailYndesvLEnhHlalafq 81 
                 YHNfrHA+dVlq++fy+l + +  +                   ++p+++l+lliaa++HDv+HpG+nN Flv+ +++la+lYnd+svLE++H+a++ q
  EEA21552.1 361 YHNFRHAVDVLQSVFYILIRIGALPTydnsntnsspskspvaslISPFDALTLLIAAIGHDVGHPGVNNVFLVKLNAPLAQLYNDSSVLESFHCAAFSQ 459
                 ******************998888668999********************************************************************* PP

                 HHTSGGG-TTTTS-HHHHHHHHHHHHHHHHTTSGGGHHHHHHHHHHHCCTTS-TTTCT......-HHHHHHHHHHHHHHHHTGCCCS-HHHHHHHHHHH CS
    PDEase_I  82 llkkeecnifknlskeeykelrkliielIlaTdmakhfelleklkelvkkkeknslnke.....eeedkklllsllikaaDisnptkpweiskkwaelv 175
                 +l+++    f+ +      ++rkl+i++IlaTdm  hf+++ ++ el++k+e+n + ++     +++ k+l++ l+ik+aDisn+++pw+i+++w++l+
  EEA21552.1 460 ILRRHWPAAFHDI------NMRKLLISSILATDMGLHFTFMGRMGELQRKYEENADITSwtpqdRDTYKTLICGLIIKCADISNVARPWKIAEQWTNLL 552
                 *****88899999......9**************************999988877776689999999999***************************** PP

                 HHHHHHHHHHHHHCT----....GGGTSSC...HHHHHHHHHHTHHHHHHHHHHC-GGGHHHHHHH CS
    PDEase_I 176 leEffeqgdeekelglpvs....plmdrektslaksqigFidfvvkplfealakllpelkelldel 237
                 +eEf +qg+ eke g+++     p    + ++l+  qi+F++ +++plfe +a l+pe++ +++++
  EEA21552.1 553 QEEFAHQGEIEKEIGMETAlfggPPELGNMQKLSLGQINFMSIFALPLFEGVAGLCPEITCTVKHI 618
                 *****************99988877777878999***************************99998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (919 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       448  (0.0249875); expected 358.6 (0.02)
Passed bias filter:                      330  (0.0184059); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.71u 0.33s 00:00:01.04 Elapsed: 00:00:00.50
# Mc/sec: 5510.00
//
Query:       EEA21553.1  [L=147]
Description: selenoprotein domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-21   76.8   0.0    1.7e-21   76.2   0.0    1.3  1  Rdx       Rdx family


Domain annotation for each model (and alignments):
>> Rdx  Rdx family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.2   0.0   9.4e-26   1.7e-21      13      74 .]       1      68 [.       1      68 [. 0.93

  Alignments for each domain:
  == domain 1  score: 76.2 bits;  conditional E-value: 9.4e-26
                HHHHHHHHHHHHHHCCCCSSEEEEEEESTT-EEEEETTE......EEEEHHHHTSS--HHHHHHHHHH CS
         Rdx 13 mlraaelaqellstfpeslgevalqpstgGaFeVtldge......lvwsrkeeggfpetkelkqrvrd 74
                mlraa++aqellstf+++lgev+l+p+tgG F+Vt+  +      l+w+rk++ggfpe+k+lk +vr+
  EEA21553.1  1 MLRAAYFAQELLSTFGTTLGEVSLRPATGGLFTVTIVPNasteemLLWDRKRDGGFPEVKQLKALVRN 68
                79***********************************44445667*********************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (147 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1507  (0.0840538); expected 358.6 (0.02)
Passed bias filter:                      585  (0.0326287); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 992.10
//
Query:       EEA21554.1  [L=593]
Description: C6 and C2H2 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.8e-09   37.0  10.6    7.2e-09   35.6  10.6    1.7  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
    5.5e-08   32.2   0.7    1.2e-07   31.0   0.7    1.6  1  Fungal_trans  Fungal specific transcription factor domain
    1.1e-06   29.0   6.0     0.0019   18.8   1.0    3.6  2  zf-C2H2_4     C2H2-type zinc finger
    3.9e-05   23.9  12.8    0.00042   20.6   0.9    3.7  4  zf-C2H2       Zinc finger, C2H2 type
     0.0047   16.9   1.3     0.0047   16.9   1.3    2.6  3  zf-C2H2_6     C2H2-type zinc finger
  ------ inclusion threshold ------
      0.019   14.7   0.2       0.07   12.9   0.2    1.9  1  zf-C2H2_11    zinc-finger C2H2-type


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.6  10.6   2.4e-12   7.2e-09       1      39 [.      88     124 ..      88     125 .. 0.94

  Alignments for each domain:
  == domain 1  score: 35.6 bits;  conditional E-value: 2.4e-12
                 SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus   1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfysesskr 39 
                 +aCd+C+  K +Cd+++P C+ C+k++l+Ct +++s kr
  EEA21554.1  88 KACDRCHALKARCDKGNP-CAICAKKGLQCT-FDRSFKR 124
                 59****************.************.9988876 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.0   0.7   4.2e-11   1.2e-07       2     107 ..     286     380 ..     285     387 .. 0.80

  Alignments for each domain:
  == domain 1  score: 31.0 bits;  conditional E-value: 4.2e-11
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLl 98 
                   +++f +fh+q+p+l kp+f+p+            +p+l+la+++ G +++e+ t    + l +    ++ f  + e ++  ++ss +  + + q+ l
    EEA21554.1 286 ELYFAHFHGQWPFLTKPQFNPEI----------EPPILVLAMVICGLRMTEEKTLMRLAWLIHAH-LHAIFVTQMENWTVKEYSSHRWPIATYQAIL 371
                   68*********************..........*********************99988888866.3333444444444566666666699999999 PP

  Fungal_trans  99 llelyekts 107
                   l+ ++ +t 
    EEA21554.1 372 LFTIFTITA 380
                   998887765 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.7   0.3   0.00026      0.78       1      23 [.      23      47 ..      23      48 .. 0.93
   2 !   18.8   1.0   6.5e-07    0.0019       1      23 [.      53      75 ..      53      76 .. 0.94

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00026
   zf-C2H2_4  1 fkCpi..CgksFsskkaLlrHlkth 23
                +kC+   Cg+s+ ++++L rH ++h
  EEA21554.1 23 YKCSDpgCGASYLRREHLIRHEAQH 47
                7899999**************9999 PP

  == domain 2  score: 18.8 bits;  conditional E-value: 6.5e-07
   zf-C2H2_4  1 fkCpiCgksFsskkaLlrHlkth 23
                + C++Cg  Fs++++L+rH ++h
  EEA21554.1 53 HVCKVCGLGFSRSDSLRRHERAH 75
                58********************9 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.4   0.3   0.00025      0.73       1      23 []      23      47 ..      23      47 .. 0.95
   2 !   20.6   0.9   1.4e-07   0.00042       1      23 []      53      75 ..      53      75 .. 0.96
   3 ?   -3.0   0.5       4.4   1.3e+04       6      12 ..     116     124 ..     106     125 .. 0.65
   4 ?   -2.0   0.0       2.2   6.5e+03       9      21 ..     180     192 ..     178     193 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00025
                EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCp..dCgksFkrksnLkrHirtH 23
                ykC+  +Cg s+ r+++L rH   H
  EEA21554.1 23 YKCSdpGCGASYLRREHLIRHEAQH 47
                99*******************8877 PP

  == domain 2  score: 20.6 bits;  conditional E-value: 1.4e-07
                EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCpdCgksFkrksnLkrHirtH 23
                ++C++Cg  F+r+++L+rH r H
  EEA21554.1 53 HVCKVCGLGFSRSDSLRRHERAH 75
                79******************998 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 4.4
                 TT..EEESS CS
     zf-C2H2   6 Cg..ksFkr 12 
                 C+  +sFkr
  EEA21554.1 116 CTfdRSFKR 124
                 555578876 PP

  == domain 4  score: -2.0 bits;  conditional E-value: 2.2
                 EESSHHHHHHHHH CS
     zf-C2H2   9 sFkrksnLkrHir 21 
                  ++++  Lk H++
  EEA21554.1 180 AYTTSAPLKLHQK 192
                 6899999****97 PP

>> zf-C2H2_6  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.7       1.3     4e+03      18      27 .]      37      46 ..      37      47 .. 0.82
   2 !   16.9   1.3   1.6e-06    0.0047       1      26 [.      52      77 ..      52      77 .. 0.94
   3 ?   -4.3   0.5         6   1.8e+04       4       9 ..      90      95 ..      90      95 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.3
   zf-C2H2_6 18 ggHkksHrke 27
                ++H+++H+++
  EEA21554.1 37 REHLIRHEAQ 46
                6899999975 PP

  == domain 2  score: 16.9 bits;  conditional E-value: 1.6e-06
   zf-C2H2_6  1 vheCsvCsksFpslqaLggHkksHrk 26
                +h+C+vC+  F+  ++L+ H + H k
  EEA21554.1 52 AHVCKVCGLGFSRSDSLRRHERAHSK 77
                69*********************975 PP

  == domain 3  score: -4.3 bits;  conditional E-value: 6
   zf-C2H2_6  4 CsvCsk 9 
                C+ C++
  EEA21554.1 90 CDRCHA 95
                999986 PP

>> zf-C2H2_11  zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.2   2.4e-05      0.07       5      23 ..      53      71 ..      50      74 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.4e-05
  zf-C2H2_11  5 cqCleCGlcftSqlsLsRH 23
                + C  CGl f+ + sL+RH
  EEA21554.1 53 HVCKVCGLGFSRSDSLRRH 71
                669**************** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (593 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       834  (0.0465168); expected 358.6 (0.02)
Passed bias filter:                      504  (0.0281109); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.62u 0.26s 00:00:00.88 Elapsed: 00:00:00.43
# Mc/sec: 4138.25
//
Query:       EEA21555.1  [L=90]
Description: G-protein complex gamma subunit GpgA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.9e-24   83.6   0.0      8e-24   83.4   0.0    1.1  1  G-gamma   GGL domain
  ------ inclusion threshold ------
       0.18   12.1   0.0       0.23   11.7   0.0    1.2  1  DUF3220   Protein of unknown function (DUF3120)


Domain annotation for each model (and alignments):
>> G-gamma  GGL domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.4   0.0   8.9e-28     8e-24       2      68 .]      21      90 .]      20      90 .] 0.97

  Alignments for each domain:
  == domain 1  score: 83.4 bits;  conditional E-value: 8.9e-28
     G-gamma  2 qlklklkrei.eqLkkeLkrerikvSkAceelidYvestkDpllpevwgppsageNpwiek..sgcCwil 68
                 lk ++++e+  +Lk++L+r+r+kvS+A+++li+Y+++t+D+++p+vwg+++++e+p++++  +gcC+++
  EEA21555.1 21 DLKYRRLTELnSRLKEDLDRPRVKVSEAALSLINYCNNTRDFMVPSVWGQVDKREDPYAPQqsGGCCTVM 90
                5899**********************************************************9999*997 PP

>> DUF3220  Protein of unknown function (DUF3120)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   2.6e-05      0.23      30      60 ..       9      39 ..       2      51 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 2.6e-05
     DUF3220 30 qgdvkvwmqnledlhtrrpdefaarlqqstd 60
                 gdvk   q + dl+ rr  e+ +rl++  d
  EEA21555.1  9 GGDVKNKKQSMADLKYRRLTELNSRLKEDLD 39
                69************************98776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (90 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       479  (0.0267165); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.45
# Mc/sec: 606.96
//
Query:       EEA21556.1  [L=1062]
Description: eukaryotic translation initiation factor 3 subunit EifCa, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      9e-12   45.4   0.4    2.4e-10   40.9   0.0    3.0  2  PCI       PCI domain
  ------ inclusion threshold ------
        4.6    6.1  41.9      0.078   12.0  26.5    2.4  2  DUF4776   Domain of unknown function (DUF4776)


Domain annotation for each model (and alignments):
>> PCI  PCI domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.1     0.074   6.6e+02      27      82 ..     169     224 ..     121     229 .. 0.79
   2 !   40.9   0.0   2.6e-14   2.4e-10       9     104 ..     398     519 ..     392     520 .. 0.92

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.074
                 HHHHHHTTHHHHHHHHHHHHHHHHHHHHHHCESEEEHHHHHHHHTSSHHHHHHHHH CS
         PCI  27 eelladdglaqllesLekkvrerllrqvskiyssislerlaklldlsvdevEkilv 82 
                 +++l+  +++  le  ++ + +++++ + k+ ++ ++ rl +ll   v+++ k++ 
  EEA21556.1 169 RTVLEILKNNARLEIMYQTTALQAFQFCLKYTRKTEFRRLCELLRNHVQNAAKYST 224
                 44555555666777777778888887777799999999999999877777766655 PP

  == domain 2  score: 40.9 bits;  conditional E-value: 2.6e-14
                 HHHHTSHHHHHHHHHHH....................HHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHCESEEEHHHHHHHHTSSH......HHHHHHH CS
         PCI   9 alrsgnlsgfseelkdl....................eeelladdglaqllesLekkvrerllrqvskiyssislerlaklldlsv......devEkil 81 
                 al++g l++++ e +dl                     +++ ad+++++++  L++++ +rl++q+s+ y+s++l+ + +l ++++      + +Ek++
  EEA21556.1 398 ALNKGLLKRARPEIRDLynilevdfhplsickkitpiLKQIGADPEMEKYVVPLQQVILTRLFQQLSQVYESVELKFVYELAQFPDpfqvtqSMIEKFI 496
                 5667778888888888888888888888888888888899*********************************************************** PP

                 HHHHHTTSSSEEEETTTTEEEEC CS
         PCI  82 vklIrdgeirakidqesgivvfk 104
                 ++  ++g ++ ++d+++g++ f 
  EEA21556.1 497 MNGCKKGDLAIRVDHVAGVLTFD 519
                 ********************985 PP

>> DUF4776  Domain of unknown function (DUF4776)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   7.4     0.043   3.8e+02     173     232 ..     597     657 ..     515     684 .. 0.48
   2 ?   12.0  26.5   8.7e-06     0.078      59     253 ..     692     885 ..     685     906 .. 0.64

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.043
     DUF4776 173 klkeeCeeaekkakkakkkrkakkklkkklkekaikkattskk.kkkkkkakkkkrrvksk 232
                 ++ke+ e  ++    +kkk+ a+++l++k++e++++k++++++ ++ +k++   ++r ++k
  EEA21556.1 597 AAKEHQETLARRVVIEKKKEAATESLQRKQREEETRKRIRTQQlQEAEKQRLLDEHREREK 657
                 3333333333333334444444444444444333333322222022222222222211111 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 8.7e-06
     DUF4776  59 kselddseedksekakkek..edeksskrctckggklctrcrirklcedifkekeelkekikkvekkeeaqslkkkedfcvrnksseskrrkkLakvfs 155
                 ++eld++  ++++ a+ ek  ++ +   r t+k  ++ +r   r+ +++i +++e++k++  +v + ++ ++lk+++ ++++++   ++r ++L+ vf+
  EEA21556.1 692 PEELDSNRLRAMKLAQLEKekNELNDRIRITAKRIDHLERAFRREELKHIPEDYEKQKQHDMEVYELQKEETLKEAQ-LKHKADVALKHRLSRLVPVFT 789
                 556666666666666666632566667788888888888888999**********9999999999888666666665.999999999************ PP

     DUF4776 156 elrdlydikkekk.k.laeklkeeCeeaekkakkakkkrkakkklkkklkekaikkattskkkkkkkkakkkkrrvkskrysflkpkekskkpkighks 252
                 e rd  ++k++++ +  ++++++e e+++k++ k+  +r++++k +   +e +++++ ++++++ +++ ++++ r +++r  + ++k ++++++++  +
  EEA21556.1 790 EFRDGLNEKRHEEfEkRRKAAERELEAKKKQRIKEVVERRRREKAE---RE-EEERRRQEEEERVRREEEERVAREEEQRRVMAERKAQREEERKKLDE 884
                 ******9999887642444445555333333333332332222222...22.22333333333444445555555555555555665555555544444 PP

     DUF4776 253 c 253
                 +
  EEA21556.1 885 I 885
                 4 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1062 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3241  (0.180769); expected 358.6 (0.02)
Passed bias filter:                      710  (0.0396006); expected 358.6 (0.02)
Passed Vit filter:                       234  (0.0130515); expected 17.9 (0.001)
Passed Fwd filter:                        59  (0.00329076); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 1.63u 0.37s 00:00:02.00 Elapsed: 00:00:00.62
# Mc/sec: 5169.94
//
Query:       EEA21557.1  [L=430]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.85    9.8   9.8      0.056   13.7   2.6    2.2  2  ATG16     Autophagy protein 16 (ATG16)


Domain annotation for each model (and alignments):
>> ATG16  Autophagy protein 16 (ATG16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.7     0.057     1e+03      49      87 ..     125     148 ..     102     179 .. 0.47
   2 ?   13.7   2.6   3.1e-06     0.056      57     145 ..     297     380 ..     278     385 .. 0.70

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.057
       ATG16  49 kssksskksakekeasasqsnskqsakiqsleqklaqlr 87 
                 + ++s+++ ++ ++ +++q              k++q r
  EEA21557.1 125 E-QTSPTHANSLQPPRNRQ--------------KTIQNR 148
                 1.12222222222222222..............111111 PP

  == domain 2  score: 13.7 bits;  conditional E-value: 3.1e-06
       ATG16  57 sakekeasasqsnskqsakiqsleqklaqlreelaelyksrgelaqrllelneelqkleeklkedeerlaeleaeraaletklkdreee 145
                  + e+++s ++++s+ +a ++s++++l      l+ l+ + ++l+  l++l+++l++ ++ +++ ++rl+++++ +a+++++ +dree 
  EEA21557.1 297 LRPESASSVRSTQSQIAAATASMDPLL-----SLQSLLGQTSDLTLTLRTLSDTLHESRQLTSTASRRLRSARELVAEIKREDEDREEG 380
                 223333332332222333333333333.....36788889999*******************************************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (430 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       658  (0.0367003); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.24s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 2835.99
//
Query:       EEA21558.1  [L=190]
Description: N-acetyltransferase (Nat5), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.2e-08   35.0   0.0      2e-08   34.2   0.0    1.4  1  Acetyltransf_10  Acetyltransferase (GNAT) domain
    1.3e-08   35.1   0.0    1.9e-08   34.5   0.0    1.3  1  Acetyltransf_1   Acetyltransferase (GNAT) family
    1.3e-06   28.7   0.0    1.9e-06   28.2   0.0    1.3  1  Acetyltransf_7   Acetyltransferase (GNAT) domain
    8.3e-06   25.7   0.0    1.4e-05   24.9   0.0    1.4  1  FR47             FR47-like protein
  ------ inclusion threshold ------
      0.067   13.3   0.1       0.12   12.5   0.1    1.4  1  Acetyltransf_9   Acetyltransferase (GNAT) domain


Domain annotation for each model (and alignments):
>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.2   0.0   5.5e-12     2e-08      31     110 ..      42     139 ..      33     146 .. 0.81

  Alignments for each domain:
  == domain 1  score: 34.2 bits;  conditional E-value: 5.5e-12
  Acetyltransf_10  31 alllvaeeggkivGvi..elrdgs..............hisllfVdpeyrgqGigkaLleaveeeaekdgikl.eltvnasp.yavpfYeklGF 106
                       + +v +++  ivG+i  +l+++               hi+ l V+p++r+ G++++L e +e+  + +++   +l v+a++  av++Y+ +G+
       EEA21558.1  42 LFSVVQDRDAGIVGYImgKLEEQPaamrhsehytpwhgHITVLTVAPAWRRLGYARRLTESLEHSSDINDSWFvDLYVRATNrVAVDMYKGMGY 135
                      56677778888888886633222245555568888889***************************977766669******************** PP

  Acetyltransf_10 107 kavg 110
                       +  
       EEA21558.1 136 SVFR 139
                      8865 PP

>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.5   0.0   5.3e-12   1.9e-08      31     117 .]      39     135 ..      15     135 .. 0.81

  Alignments for each domain:
  == domain 1  score: 34.5 bits;  conditional E-value: 5.3e-12
                     TTC.EEEEEEETTEEEEEEEEEEEET.........TSTTEEEEEEEEESGGGTTSSHHHHHHHHHHHHHHHTTESEEEEEEETTEHHHHHHHHH. CS
  Acetyltransf_1  31 eae.gllvaeedgeliGfisllkipd.........ekggvayieslaVspeyrgkGlGsaLlealeerareegikkivlaveedndaairlYek. 114
                      ++ + +v  +d  ++G+i+++   +           + +++i  l V+p++r+ G++++L e le+    +    + l+v+++n+ a+ +Y k 
      EEA21558.1  39 WPSlFSVVQDRDAGIVGYIMGKLEEQpaamrhsehYTPWHGHITVLTVAPAWRRLGYARRLTESLEHSSDINDSWFVDLYVRATNRVAVDMY-Kg 132
                     44423334344455*****9999999999999999778****************************9666666666789*************.88 PP

                     TTE CS
  Acetyltransf_1 115 lGF 117
                     +G+
      EEA21558.1 133 MGY 135
                     998 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.2   0.0   5.3e-10   1.9e-06       7      75 ..      46     136 ..      24     137 .. 0.74

  Alignments for each domain:
  == domain 1  score: 28.2 bits;  conditional E-value: 5.3e-10
                     EEEETTEEEEEEEEEEES...............TCTEEEEE-GGGTTSSHHHHHHH.HTT.SEEE....EEEEEE..THHHHHHHHHHTTEE CS
  Acetyltransf_7   7 VaeddgkivGfialslld...............aeitrlaVdpeyrgkGiGraLle.aae.kgii....leqlel..naekaikfYeklGFe 75 
                     V ++d +ivG+i  +l++               ++it l V+p++r+ G++r+L e +++ + i+    +  l++  +++ a+++Y+ +G+ 
      EEA21558.1  46 VQDRDAGIVGYIMGKLEEqpaamrhsehytpwhGHITVLTVAPAWRRLGYARRLTEsLEHsSDINdswfV-DLYVraTNRVAVDMYKGMGYS 136
                     344558999999999999999999999888776666669***************9943234333333221.33444233499********96 PP

>> FR47  FR47-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.9   0.0     4e-09   1.4e-05      19      80 ..      76     138 ..      57     144 .. 0.84

  Alignments for each domain:
  == domain 1  score: 24.9 bits;  conditional E-value: 4e-09
                 -TTSSEEEEEE-GGG-SSSHHHHHHHHHHHHHHH.S-S-EEEEEETT-HHHHHHHHHHT-EEE CS
        FR47  19 kdggelgalqvlpehrrrGlgsrlvkalakeiae.rgktvllvvvasNtpsirlyeklGfeki 80 
                 +  g +  l v p  rr G+++rl+++l +         v l+v+a+N  +  +y+ +G+ + 
  EEA21558.1  76 PWHGHITVLTVAPAWRRLGYARRLTESLEHSSDInDSWFVDLYVRATNRVAVDMYKGMGYSVF 138
                 55699***********************98765525556779******************875 PP

>> Acetyltransf_9  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.1   3.3e-05      0.12      53     127 ..      57     137 ..      43     138 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 3.3e-05
                     EEEEEEEEEEEEEETTEEEEE.EEEEEEEE-CCGTTS-HHHHHHHHHHHHHHHTT--EEEE--.....SSHHHHHTTT-EE CS
  Acetyltransf_9  53 lvgqlallplelnvpGktlka.agvtgVavapehrgrgvlskLlaraleemreegqplsllfP.....ssipiYrrfGyei 127
                     ++g+l   p  ++  +  ++  + +t  +vap  r+ g++++L++ +    + ++ +++ l+       ++++Y+ +Gy++
      EEA21558.1  57 IMGKLEEQPAAMRHSEHYTPWhGHITVLTVAPAWRRLGYARRLTESLEHSSDINDSWFVDLYVratnrVAVDMYKGMGYSV 137
                     5666666677777777666665889999**********************************97776666799*****975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (190 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       292  (0.0162865); expected 358.6 (0.02)
Passed bias filter:                      277  (0.0154498); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.46
# Mc/sec: 1242.81
//
Query:       EEA21559.1  [L=408]
Description: MFS monocarboxylate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.5e-12   45.6  55.9    2.5e-09   36.6  17.3    2.1  2  MFS_1        Major Facilitator Superfamily
  ------ inclusion threshold ------
        3.2    6.8   7.5        5.9    6.0   7.5    1.5  1  Herpes_LMP1  Herpesvirus latent membrane protein 1 (LMP1)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.6  17.3   2.7e-13   2.5e-09       5     139 ..      64     203 ..      60     205 .. 0.78
   2 !   14.9  30.6     1e-06    0.0094       2     170 ..     224     393 ..     222     406 .. 0.85

  Alignments for each domain:
  == domain 1  score: 36.6 bits;  conditional E-value: 2.7e-13
       MFS_1   5 aflsalarsi...lgpalplalaed...lgispseigllltlyalgaavaslplGrlsdrfGrrr.vlllglllfalglllll.fasslw.lllvlrvl 94 
                 af+ +++ +    ++ a+  ++ e+    + s+s+i+++ ++ +++ ++  ++ G+l d  G  + +l lg ++ ++g ++++ +a++++ ++l+  + 
  EEA21559.1  64 AFFLFFNTWGlinTWGAFQ-TYYEEhilSHESASTISWIGSIESFLLMFIGVVSGPLFDA-GYLPvLLPLGSFMVVFG-YMMTsLATGYYqVMLAQGIC 159
                 4444444444111333333.333332332379999************************8.99995666666666666.888877899999******** PP

       MFS_1  95 qGlgagalfpagaaliadwfpkeergraigllsagfslGailgpl 139
                  Glg+g+lf  ++al+ ++f k +r++a+gl+++g+s+G ++ p+
  EEA21559.1 160 VGLGTGFLFVPSVALLPQYFRK-KRALANGLAASGSSFGGVIYPI 203
                 **********************.*******************997 PP

  == domain 2  score: 14.9 bits;  conditional E-value: 1e-06
       MFS_1   2 llaaflsalarsilgpalpl.alaedlgispseigl.lltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGl 97 
                 +l++f+ +l+++++++ + + a+  + gi  s +g+ l+++  ++++++ +    ++d  G+  +ll ++ ++al+ +++++a +++  +++l +l G+
  EEA21559.1 224 CLGLFMGFLGFYNFLIYVQPwAI--QNGIVNSNLGFyLVSILNAASIFGRIAPNLIADYTGPLNILLPAASFTALM-AFCWIAVNSTaGIIILALLYGF 319
                 78999999999999999987455..4579999999989999999999999999***********************.555545666669********** PP

       MFS_1  98 gagalfpagaaliadwfpk.eergraigllsagfslGailgpllggllasslg.Wravfyilaivsllafvlfll 170
                 ++g+++++  +++ +++++ ++ g  +g+  +  s++ ++g ++gg+++s+++ + +v +++++ +++++v+ +l
  EEA21559.1 320 FSGGFVSLPPVVMMAITKDfRDLGTRLGMCFSLCSIALLVGTPIGGAILSAGNsYLGVQLFCGACLAVCAVV-IL 393
                 **********************************************99966665777777777777777774.22 PP

>> Herpes_LMP1  Herpesvirus latent membrane protein 1 (LMP1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   7.5   0.00066       5.9      34     135 ..     294     406 ..     273     408 .] 0.68

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.00066
                  XXXXXXXXXXXXXXXXXXXX.XXXXX.....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Herpes_LMP1  34 lallfwlyivmsdwtggall.vlysf.....allliiiiliififrrdllcplgalcllllmitlll...ialwnlhgqalylgivlfifgcllvlgl 122
                   al+ + +i ++  +g  +l +ly f       l  ++++ i    rdl   lg +c+ l  i+ll+   i    l     ylg+ lf   cl v  +
   EEA21559.1 294 TALMAFCWIAVNSTAGIIILaLLYGFfsggfVSLPPVVMMAITKDFRDLGTRLG-MCFSLCSIALLVgtpIGGAILSAGNSYLGVQLFCGACLAVCAV 390
                  466666777776666665542466652221123333555666666799999998.68888888888744456667889999************99988 PP

                  XXXXXXXX...XXXXX CS
  Herpes_LMP1 123 wiyllell...wrlga 135
                   i ++ ++   wrl a
   EEA21559.1 391 VILIIRVIrvgWRLTA 406
                  7776554333399877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (408 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       822  (0.0458475); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.48
# Mc/sec: 2580.08
//
Query:       EEA21560.1  [L=1216]
Description: PH domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      3e-07   30.9   0.0    2.5e-06   28.0   0.0    2.4  2  PH        PH domain
     0.0086   16.4   0.0      0.022   15.1   0.0    1.7  1  PH_9      Pleckstrin homology domain


Domain annotation for each model (and alignments):
>> PH  PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.0   0.0   2.8e-10   2.5e-06       4     104 ..     110     222 ..     107     223 .. 0.79
   2 ?   -0.3   0.0      0.17   1.6e+03      17      28 ..     271     282 ..     256     332 .. 0.67

  Alignments for each domain:
  == domain 1  score: 28.0 bits;  conditional E-value: 2.8e-10
                 EEEEEEETSSSSC.......SEEEEEEEEETTEEEEESST...TCTTESSEEEEEESTTEEEEEEEC.....TTSSSSTSEEEEEESTSSSTEEEEEEE CS
          PH   4 eGwLlkkgsgkkk.......swkkrwfvLkdsellyyknd...ksekdkepkgsislsncevvevva.....tedpkrkfcfelriverngsrtyllqa 87 
                 eG++lk    +         +w ++++vL++++l+++++     +  +    ++i+l++++++  ++     ++ ++  + +++  ++ ++ ++yl+++
  EEA21560.1 110 EGYFLKLNDLDTHgrpcadrKWVECFAVLTGTVLSIWDAAaldATGNQDITPTFINLTDASIKMLETlptydKNAKPLQNILSV--STAGR-NRYLFHF 205
                 77755555444445677889**********************977777777888*********9999*9754445555555555..55588.******* PP

                 SSHHHHHHHHHHHHHHH CS
          PH  88 sseeerkeWikaiqsai 104
                 +s  ++++W ++i+ a+
  EEA21560.1 206 NSLNSLTQWTASIRLAL 222
                 *************9875 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.17
                 SEEEEEEEEETT CS
          PH  17 swkkrwfvLkds 28 
                  w+++wfv++  
  EEA21560.1 271 PWRRCWFVVTPP 282
                 699999998854 PP

>> PH_9  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   2.4e-06     0.022       7     114 ..     114     218 ..     108     221 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 2.4e-06
        PH_9   7 qrkllleskgkktplkkrgWkevyavlkklvLylykdeeesesae...tedlkslknakllgkirlhhaLaekasdYkkkshvFrLqtadgaeylfqts 102
                  + + l+++g+  p  +r+W e++avl ++vL +        +++   t+++ +l +a    +i++  +L +  ++ k  +++  + ta +  ylf  +
  EEA21560.1 114 LKLNDLDTHGR--PCADRKWVECFAVLTGTVLSIWDAAALDATGNqdiTPTFINLTDA----SIKMLETLPTYDKNAKPLQNILSVSTAGRNRYLFHFN 206
                 55555555554..569******************999554444330003334444555....9*******9998888889******************* PP

        PH_9 103 dakevqeWvdti 114
                 + + + +W   i
  EEA21560.1 207 SLNSLTQWTASI 218
                 ********8766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1216 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       658  (0.0367003); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.75u 0.31s 00:00:01.06 Elapsed: 00:00:00.48
# Mc/sec: 7577.61
//
Query:       EEA21561.1  [L=560]
Description: C2H2 transcription factor (TFIIIA), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.4e-27   93.8  58.8    5.9e-05   23.3   0.1   11.2 11  zf-C2H2        Zinc finger, C2H2 type
    3.1e-21   74.2  55.5      0.025   15.4   0.1   10.7 10  zf-C2H2_4      C2H2-type zinc finger
    6.5e-08   32.7  64.4    0.00041   20.7   1.1   11.5 12  zf-H2C2_2      Zinc-finger double domain
    1.1e-05   26.0  31.0        1.3    9.7   0.0    9.2 10  FOXP-CC        FOXP coiled-coil domain
    0.00036   20.2  15.2        1.1    9.1   4.0    6.3  5  zf_Hakai       C2H2 Hakai zinc finger domain
    0.00045   20.5  25.3      0.032   14.5   2.0    4.8  5  zf-C2H2_8      C2H2-type zinc ribbon
    0.00054   19.7   4.1     0.0007   19.4   1.0    2.7  3  GAGA           GAGA factor
    0.00069   19.8  24.9        5.4    7.4   0.1    8.9 10  zf-C2H2_jaz    Zinc-finger double-stranded RNA-binding
    0.00089   19.0   1.0    0.00089   19.0   1.0    9.2 10  zf-H2C2_5      C2H2-type zinc-finger domain
  ------ inclusion threshold ------
      0.012   16.3  22.0        3.1    8.5   0.4    6.0  6  zf-C2H2_3rep   Zinc finger C2H2-type, 3 repeats
      0.036   13.8  20.9       0.16   11.7   0.0    5.8  6  zf-C2H2_11     zinc-finger C2H2-type
       0.32   11.5  20.1         12    6.4   0.0    7.6  9  zf-met         Zinc-finger of C2H2 type
       0.86    9.7   0.0       0.86    9.7   0.0    7.8 10  zf-C2H2_6      C2H2-type zinc finger
        1.2    9.0  11.9          7    6.6   0.3    5.0  5  zf-C2H2_9      C2H2 type zinc-finger (1 copy)
        8.5    6.4  18.1         13    5.9   0.0    4.5  4  Ogr_Delta      Ogr/Delta-like zinc finger


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.1      0.64   7.7e+02       9      20 ..      62      73 ..      60      74 .. 0.85
   2 !   17.0   0.4   4.8e-06    0.0057       3      23 .]      74      96 ..      72      96 .. 0.95
   3 !   10.3   5.8   0.00068      0.81       1      23 []     102     127 ..     102     127 .. 0.95
   4 !   12.1   0.1   0.00017      0.21       1      23 []     133     157 ..     133     157 .. 0.94
   5 !    9.2   0.7    0.0015       1.8       2      23 .]     164     189 ..     163     189 .. 0.85
   6 !    7.8   0.2    0.0041       4.9       5      23 .]     207     226 ..     195     226 .. 0.85
   7 !    8.4   0.1    0.0027       3.2       1      23 []     231     257 ..     231     257 .. 0.92
   8 !   10.0   3.4   0.00082      0.98       2      23 .]     260     282 ..     260     282 .. 0.94
   9 !   23.3   0.1   4.9e-08   5.9e-05       1      23 []     293     318 ..     293     318 .. 0.96
  10 !   11.3   0.0   0.00031      0.37       6      23 .]     346     364 ..     344     364 .. 0.97
  11 !   15.7   0.5   1.3e-05     0.015       3      23 .]     414     437 ..     413     437 .. 0.91

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.64
                EESSHHHHHHHH CS
     zf-C2H2  9 sFkrksnLkrHi 20
                s k +s+Lk+H+
  EEA21561.1 62 SSKYPSELKTHL 73
                6789*******8 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 4.8e-06
                ET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2  3 Cp..dCgksFkrksnLkrHirtH 23
                Cp  +C+k F+r+  L+ H+r+H
  EEA21561.1 74 CPfdGCTKAFNRPARLQEHLRSH 96
                9999******************9 PP

  == domain 3  score: 10.3 bits;  conditional E-value: 0.00068
                 EEET..TTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirt.H 23 
                 + C+   C+k+F r s+L++Hi++ H
  EEA21561.1 102 FHCTydNCDKTFLRVSHLNHHIKSaH 127
                 789999*****************999 PP

  == domain 4  score: 12.1 bits;  conditional E-value: 0.00017
                 EEET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirtH 23 
                 y C+  +Cgk F +   L+rH+  H
  EEA21561.1 133 YICDrpGCGKAFVTGTRLRRHLAAH 157
                 789999***************9887 PP

  == domain 5  score: 9.2 bits;  conditional E-value: 0.0015
                 EET...TTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   2 kCp...dCgksFkrksnLkrHirt.H 23 
                 +C+    C+++F+    L +Hi++ H
  EEA21561.1 164 RCTeypPCNETFRKHATLAQHIMSiH 189
                 5666556****************999 PP

  == domain 6  score: 7.8 bits;  conditional E-value: 0.0041
                 TTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   5 dCgksFkrksnLkrHirt.H 23 
                 +C++ F +  +L+ H ++ H
  EEA21561.1 207 KCSQAFDTAAHLRGHENRvH 226
                 8**************99999 PP

  == domain 7  score: 8.4 bits;  conditional E-value: 0.0027
                 EEETTTT...EEESSHHHHHHHHHC.C CS
     zf-C2H2   1 ykCpdCg...ksFkrksnLkrHirt.H 23 
                 ++C++C     sF +  +L++Hi++ H
  EEA21561.1 231 FTCTECMssdLSFASYAELQAHIKSvH 257
                 78999988889*************999 PP

  == domain 8  score: 10.0 bits;  conditional E-value: 0.00082
                 EETTTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   2 kCpdCgksFkrksnLkrHirt.H 23 
                 +Cp+C+  + ++ +L+rH+ + H
  EEA21561.1 260 ECPHCSFQCETSRELRRHLEIsH 282
                 5*****************99888 PP

  == domain 9  score: 23.3 bits;  conditional E-value: 4.9e-08
                 EEET..TTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirt.H 23 
                 + C+  +Cg+sF+ k nL +H rt H
  EEA21561.1 293 FSCTvpGCGRSFTKKGNLAVHVRTvH 318
                 789999******************99 PP

  == domain 10  score: 11.3 bits;  conditional E-value: 0.00031
                 TTEEESSHHHHHHHHHC.C CS
     zf-C2H2   6 CgksFkrksnLkrHirt.H 23 
                 Cgk++++k  L+ H rt H
  EEA21561.1 346 CGKRYSSKIALEEHVRTtH 364
                 *****************99 PP

  == domain 11  score: 15.7 bits;  conditional E-value: 1.3e-05
                 ET..TTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   3 Cp..dCgksFkrksnLkrHirt.H 23 
                 C   dC ++F r ++L +H+r+ H
  EEA21561.1 414 CFasDCRYRFYREYDLWVHMRSkH 437
                 66669****************999 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.3   0.4   0.00021      0.25       2      23 ..      73      96 ..      64      97 .. 0.95
   2 !   10.8   4.8   0.00063      0.75       1      24 []     102     127 ..     102     127 .. 0.96
   3 !   13.3   0.0   9.8e-05      0.12       1      23 [.     133     157 ..     133     158 .. 0.90
   4 !    7.1   0.5    0.0098        12       1      24 []     163     189 ..     163     189 .. 0.87
   5 !    7.9   0.1    0.0053       6.3       5      24 .]     207     226 ..     195     226 .. 0.90
   6 !   12.5   0.2   0.00018      0.22       1      24 []     231     257 ..     231     257 .. 0.97
   7 !   12.2   2.9   0.00022      0.26       2      24 .]     260     282 ..     259     282 .. 0.77
   8 !   15.4   0.1   2.1e-05     0.025       1      24 []     293     318 ..     293     318 .. 0.92
   9 !    8.6   0.0    0.0031       3.7       6      24 .]     346     364 ..     344     364 .. 0.94
  10 ?    5.5   0.4     0.032        38       5      24 .]     418     437 ..     417     437 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00021
   zf-C2H2_4  2 kCpi..CgksFsskkaLlrHlkth 23
                 Cp+  C+k F+++ +L+ Hl++h
  EEA21561.1 73 LCPFdgCTKAFNRPARLQEHLRSH 96
                699999*****************9 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00063
   zf-C2H2_4   1 fkCpi..CgksFsskkaLlrHlkthH 24 
                 f C++  C+k+F + ++L++H+k+ H
  EEA21561.1 102 FHCTYdnCDKTFLRVSHLNHHIKSAH 127
                 79*********************988 PP

  == domain 3  score: 13.3 bits;  conditional E-value: 9.8e-05
   zf-C2H2_4   1 fkCpi..CgksFsskkaLlrHlkth 23 
                 ++C+   Cgk F + ++L+rHl++h
  EEA21561.1 133 YICDRpgCGKAFVTGTRLRRHLAAH 157
                 6777777****************99 PP

  == domain 4  score: 7.1 bits;  conditional E-value: 0.0098
   zf-C2H2_4   1 fkCpi...CgksFsskkaLlrHlkthH 24 
                 f+C+    C+++F+ + +L +H+ + H
  EEA21561.1 163 FRCTEyppCNETFRKHATLAQHIMSIH 189
                 78888888*****88888****99877 PP

  == domain 5  score: 7.9 bits;  conditional E-value: 0.0053
   zf-C2H2_4   5 iCgksFsskkaLlrHlkthH 24 
                  C++ F +  +L+ H +++H
  EEA21561.1 207 KCSQAFDTAAHLRGHENRVH 226
                 4*****************99 PP

  == domain 6  score: 12.5 bits;  conditional E-value: 0.00018
   zf-C2H2_4   1 fkCpiC...gksFsskkaLlrHlkthH 24 
                 f+C+ C   + sF s+ +L+ H+k++H
  EEA21561.1 231 FTCTECmssDLSFASYAELQAHIKSVH 257
                 89************************9 PP

  == domain 7  score: 12.2 bits;  conditional E-value: 0.00022
   zf-C2H2_4   2 kCpiCgksFsskkaLlrHlkthH 24 
                 +Cp+C+  + ++++L+rHl+  H
  EEA21561.1 260 ECPHCSFQCETSRELRRHLEISH 282
                 7****666666666*****9877 PP

  == domain 8  score: 15.4 bits;  conditional E-value: 2.1e-05
   zf-C2H2_4   1 fkCpi..CgksFsskkaLlrHlkthH 24 
                 f C++  Cg+sF+ k +L  H++t+H
  EEA21561.1 293 FSCTVpgCGRSFTKKGNLAVHVRTVH 318
                 7899999*****88888********9 PP

  == domain 9  score: 8.6 bits;  conditional E-value: 0.0031
   zf-C2H2_4   6 CgksFsskkaLlrHlkthH 24 
                 Cgk++ssk aL  H++t H
  EEA21561.1 346 CGKRYSSKIALEEHVRTTH 364
                 ****************988 PP

  == domain 10  score: 5.5 bits;  conditional E-value: 0.032
   zf-C2H2_4   5 iCgksFsskkaLlrHlkthH 24 
                  C+ +F + ++L  H+++ H
  EEA21561.1 418 DCRYRFYREYDLWVHMRSKH 437
                 599999999*********99 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.5      0.54   6.5e+02      13      25 ..      70      84 ..      64      85 .. 0.79
   2 !   20.7   1.1   3.4e-07   0.00041       2      25 ..      89     114 ..      88     115 .. 0.93
   3 !    8.9   0.4    0.0018       2.2       1      26 []     118     146 ..     118     146 .. 0.94
   4 !    8.5   0.8    0.0024       2.9       2      24 ..     150     175 ..     149     177 .. 0.88
   5 !    8.8   0.1    0.0019       2.3       2      23 ..     181     211 ..     180     214 .. 0.69
   6 !    7.5   0.6    0.0051       6.1       1      20 [.     217     236 ..     216     239 .. 0.79
   7 ?    5.8   2.2     0.017        21       2      22 ..     249     266 ..     248     270 .. 0.72
   8 ?    1.9   0.1      0.28   3.4e+02       2      25 ..     274     305 ..     273     306 .. 0.67
   9 !    9.5   0.0    0.0011       1.3       1      17 [.     309     326 ..     309     328 .. 0.88
  10 ?   -2.8   0.1       9.1   1.1e+04      19      25 ..     345     351 ..     344     352 .. 0.81
  11 ?   -0.7   0.1         2   2.4e+03       1      11 [.     355     366 ..     355     367 .. 0.81
  12 ?    1.0   0.1      0.56   6.7e+02       1       9 [.     428     437 ..     428     440 .. 0.78

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.54
   zf-H2C2_2 13 kpyeCp..lCdkaFk 25
                k + Cp   C kaF+
  EEA21561.1 70 KTHLCPfdGCTKAFN 84
                458899655*****8 PP

  == domain 2  score: 20.7 bits;  conditional E-value: 3.4e-07
   zf-H2C2_2   2 LrrHirkHtgekpyeCp..lCdkaFk 25 
                 L+ H+r+H +e++++C    Cdk+F 
  EEA21561.1  89 LQEHLRSHNNERIFHCTydNCDKTFL 114
                 899**************999*****6 PP

  == domain 3  score: 8.9 bits;  conditional E-value: 0.0018
   zf-H2C2_2   1 nLrrHirk.HtgekpyeCp..lCdkaFkt 26 
                 +L+ Hi++ Ht  + y C+   C+kaF+t
  EEA21561.1 118 HLNHHIKSaHTAVRDYICDrpGCGKAFVT 146
                 7999****************99*****86 PP

  == domain 4  score: 8.5 bits;  conditional E-value: 0.0024
   zf-H2C2_2   2 LrrHirkHtgekpyeCp...lCdkaF 24 
                 LrrH++ H g  ++ C     C+ +F
  EEA21561.1 150 LRRHLAAHDGRDKFRCTeypPCNETF 175
                 9*************998777899998 PP

  == domain 5  score: 8.8 bits;  conditional E-value: 0.0019
   zf-H2C2_2   2 LrrHirk.HtgekpyeCp........lCdka 23 
                 L +Hi + H ++kp+ C         +C+ a
  EEA21561.1 181 LAQHIMSiHLKQKPFPCQyinpttgqKCSQA 211
                 66897644*********85555555555555 PP

  == domain 6  score: 7.5 bits;  conditional E-value: 0.0051
   zf-H2C2_2   1 nLrrHirkHtgekpyeCplC 20 
                 +Lr H    ++e++++C +C
  EEA21561.1 217 HLRGHENRVHSESRFTCTEC 236
                 46667766669********* PP

  == domain 7  score: 5.8 bits;  conditional E-value: 0.017
   zf-H2C2_2   2 LrrHirk.HtgekpyeCplCdk 22 
                 L+ Hi++ H++    eCp C+ 
  EEA21561.1 249 LQAHIKSvHPP----ECPHCSF 266
                 899***74777....6777764 PP

  == domain 8  score: 1.9 bits;  conditional E-value: 0.28
   zf-H2C2_2   2 LrrHirk.Ht....gekp.yeCp..lCdkaFk 25 
                 LrrH+   H      e++ + C    C+ +F+
  EEA21561.1 274 LRRHLEIsHGdvslEERRqFSCTvpGCGRSFT 305
                 89998642776666554458888667999987 PP

  == domain 9  score: 9.5 bits;  conditional E-value: 0.0011
   zf-H2C2_2   1 nLrrHirk.HtgekpyeC 17 
                 nL  H r+ H gek++ C
  EEA21561.1 309 NLAVHVRTvHEGEKRFVC 326
                 6888***66********* PP

  == domain 10  score: -2.8 bits;  conditional E-value: 9.1
   zf-H2C2_2  19 lCdkaFk 25 
                 +C+k+++
  EEA21561.1 345 ACGKRYS 351
                 7***997 PP

  == domain 11  score: -0.7 bits;  conditional E-value: 2
   zf-H2C2_2   1 nLrrHirk.Htg 11 
                 +L+ H r+ H g
  EEA21561.1 355 ALEEHVRTtHLG 366
                 6999***66976 PP

  == domain 12  score: 1.0 bits;  conditional E-value: 0.56
   zf-H2C2_2   1 nLrrHirk.H 9  
                 +L+ H+r+ H
  EEA21561.1 428 DLWVHMRSkH 437
                 6999***626 PP

>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.1     0.045        53       5      29 ..      72      96 ..      69     100 .. 0.87
   2 !    8.1   0.3    0.0034         4       6      32 ..     103     129 ..     102     134 .. 0.92
   3 ?    6.5   0.0     0.011        13       6      29 ..     134     157 ..     130     166 .. 0.83
   4 ?    4.7   0.3      0.04        47       8      33 ..     167     192 ..     161     199 .. 0.86
   5 ?    0.9   0.5       0.6   7.2e+02      12      39 ..     208     235 ..     206     240 .. 0.84
   6 ?    1.6   1.9      0.36   4.4e+02      16      49 ..     243     277 ..     232     281 .. 0.68
   7 ?    3.9   0.4     0.071        85      10      31 ..     262     283 ..     259     293 .. 0.89
   8 !    9.7   0.0    0.0011       1.3       6      35 ..     294     323 ..     290     329 .. 0.90
   9 ?   -1.1   0.0       2.6   3.1e+03      12      40 ..     346     374 ..     344     380 .. 0.78
  10 ?    2.3   0.0      0.23   2.7e+02       7      46 ..     414     453 ..     410     460 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.045
     FOXP-CC  5 gvCkWPgCekvledveeflkhlnse 29
                 +C   gC k+++  +++++hl+s+
  EEA21561.1 72 HLCPFDGCTKAFNRPARLQEHLRSH 96
                679999****************875 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0034
     FOXP-CC   6 vCkWPgCekvledveeflkhlnseHal 32 
                 +C   +C+k +  v+++ +h++s+H+ 
  EEA21561.1 103 HCTYDNCDKTFLRVSHLNHHIKSAHTA 129
                 59999********************85 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.011
     FOXP-CC   6 vCkWPgCekvledveeflkhlnse 29 
                 +C+ PgC k++ + +++ +hl  +
  EEA21561.1 134 ICDRPGCGKAFVTGTRLRRHLAAH 157
                 79******************9753 PP

  == domain 4  score: 4.7 bits;  conditional E-value: 0.04
     FOXP-CC   8 kWPgCekvledveeflkhlnseHald 33 
                 + P C++ + +++++ +h+ s H  +
  EEA21561.1 167 EYPPCNETFRKHATLAQHIMSIHLKQ 192
                 589*****************999765 PP

  == domain 5  score: 0.9 bits;  conditional E-value: 0.6
     FOXP-CC  12 CekvledveeflkhlnseHalddkstaq 39 
                 C++++++++++  h n+ H+ +  +  +
  EEA21561.1 208 CSQAFDTAAHLRGHENRVHSESRFTCTE 235
                 9******************987666555 PP

  == domain 6  score: 1.6 bits;  conditional E-value: 0.36
     FOXP-CC  16 ledveeflkhlnseHal.ddkstaqlrvqmqvvqq 49 
                 + +++e+++h++s H + + ++  q++   ++ ++
  EEA21561.1 243 FASYAELQAHIKSVHPPeCPHCSFQCETSRELRRH 277
                 66778888888888876246677777766555444 PP

  == domain 7  score: 3.9 bits;  conditional E-value: 0.071
     FOXP-CC  10 PgCekvledveeflkhlnseHa 31 
                 P C+  +e++ e+ +hl+ +H 
  EEA21561.1 262 PHCSFQCETSRELRRHLEISHG 283
                 99***************99995 PP

  == domain 8  score: 9.7 bits;  conditional E-value: 0.0011
     FOXP-CC   6 vCkWPgCekvledveeflkhlnseHalddk 35 
                  C  PgC + +++ +++  h+++ H+ +++
  EEA21561.1 294 SCTVPGCGRSFTKKGNLAVHVRTVHEGEKR 323
                 6999*********************98776 PP

  == domain 9  score: -1.1 bits;  conditional E-value: 2.6
     FOXP-CC  12 CekvledveeflkhlnseHalddkstaql 40 
                 C k  ++  ++ +h++++H    +s a+ 
  EEA21561.1 346 CGKRYSSKIALEEHVRTTHLGLMNSKAEQ 374
                 8888889999999****998666666655 PP

  == domain 10  score: 2.3 bits;  conditional E-value: 0.23
     FOXP-CC   7 CkWPgCekvledveeflkhlnseHalddkstaqlrvqmqv 46 
                 C   +C   +    ++  h++s+H  +++ ++ l +   +
  EEA21561.1 414 CFASDCRYRFYREYDLWVHMRSKHGYEERDIENLFMERAL 453
                 6666899999999999************999888776655 PP

>> zf_Hakai  C2H2 Hakai zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   4.0   0.00088       1.1       3      30 ..     101     127 ..     100     129 .. 0.94
   2 ?    1.7   0.3      0.18   2.1e+02       4      32 .]     163     191 ..     162     191 .. 0.92
   3 ?    4.8   0.0      0.02        23      18      30 ..     245     257 ..     231     258 .. 0.77
   4 ?    4.2   0.0     0.029        35       4      28 ..     293     316 ..     292     319 .. 0.86
   5 ?    1.7   0.0      0.18   2.1e+02       8      30 ..     328     364 ..     324     365 .. 0.71

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00088
    zf_Hakai   3 vFmCtvvegCrRTYLSqRDLqAHIkhRH 30 
                 +F Ct+ ++C  T+L    L+ HIk  H
  EEA21561.1 101 IFHCTY-DNCDKTFLRVSHLNHHIKSAH 127
                 8*****.*****************9888 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.18
    zf_Hakai   4 FmCtvvegCrRTYLSqRDLqAHIkhRHlr 32 
                 F Ct    C  T+  +  L  HI   Hl+
  EEA21561.1 163 FRCTEYPPCNETFRKHATLAQHIMSIHLK 191
                 88*********************998886 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.02
    zf_Hakai  18 SqRDLqAHIkhRH 30 
                 S  +LqAHIk  H
  EEA21561.1 245 SYAELQAHIKSVH 257
                 6678*****9766 PP

  == domain 4  score: 4.2 bits;  conditional E-value: 0.029
    zf_Hakai   4 FmCtvvegCrRTYLSqRDLqAHIkh 28 
                 F Ctv  gC R +  + +L  H+  
  EEA21561.1 293 FSCTV-PGCGRSFTKKGNLAVHVRT 316
                 89**9.*****99999999999876 PP

  == domain 5  score: 1.7 bits;  conditional E-value: 0.18
    zf_Hakai   8 v..............vegCrRTYLSqRDLqAHIkhRH 30 
                                 + C   Y S+  L+ H+   H
  EEA21561.1 328 EtdlssskkvegwtgADACGKRYSSKIALEEHVRTTH 364
                 555555555555555789***************9888 PP

>> zf-C2H2_8  C2H2-type zinc ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   2.0   2.7e-05     0.032       2      87 ..      74     155 ..      73     161 .. 0.88
   2 ?    3.7   0.7     0.064        76       3      62 ..     136     191 ..     135     201 .. 0.51
   3 !    7.2   5.7    0.0051         6      16      89 ..     213     281 ..     193     286 .. 0.72
   4 !   12.0   1.0   0.00016       0.2       5      71 ..     262     328 ..     258     336 .. 0.86
   5 ?   -1.1   0.0         2   2.4e+03      32      57 ..     408     433 ..     385     447 .. 0.65

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 2.7e-05
   zf-C2H2_8   2 cssygcrlafpnvrelaqhlrvhlsptqslegklfrcstascaetfpsmqelvahtklhykpnryfkcen..cllrfrthrslfkhlh 87 
                 c   gc+ af  +  l +hlr+h +       ++f+c+   c +tf  +  l  h k  +   r + c+   c   f t   l +hl 
  EEA21561.1  74 CPFDGCTKAFNRPARLQEHLRSHNN------ERIFHCTYDNCDKTFLRVSHLNHHIKSAHTAVRDYICDRpgCGKAFVTGTRLRRHLA 155
                 6778************999999864......689**********************************85449899999988888885 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.064
   zf-C2H2_8   3 ssygcrlafpnvrelaqhlrvhlsptqslegklfrcst.ascaetfpsmqelvaht.klhyk 62 
                   +gc  af +   l +hl +h          +frc+  + c etf     l  h   +h k
  EEA21561.1 136 DRPGCGKAFVTGTRLRRHLAAHD----G--RDKFRCTEyPPCNETFRKHATLAQHImSIHLK 191
                 45555555555444444443332....1..23577764256777777777776664134443 PP

  == domain 3  score: 7.2 bits;  conditional E-value: 0.0051
   zf-C2H2_8  16 elaqhlrvhlsptqslegklfrcst.ascaetfpsmqelvahtklhykpnryfkcencllrfrthrslfkhlhvc 89 
                 + a hlr h +  +     +f c+  +s   +f s  el ah k  + p     c  c ++  t r l +hl + 
  EEA21561.1 213 DTAAHLRGHENRVH--SESRFTCTEcMSSDLSFASYAELQAHIKSVHPP----ECPHCSFQCETSRELRRHLEIS 281
                 34455555544433..3468888751566679********999988877....5999999999999999999875 PP

  == domain 4  score: 12.0 bits;  conditional E-value: 0.00016
   zf-C2H2_8   5 ygcrlafpnvrelaqhlrvhlsptqslegklfrcstascaetfpsmqelvahtklhykpnryfkcen 71 
                 + c +   ++rel +hl+         e ++f c+ + c  +f    +l  h +  +  ++ f c +
  EEA21561.1 262 PHCSFQCETSRELRRHLEISHGDVSLEERRQFSCTVPGCGRSFTKKGNLAVHVRTVHEGEKRFVCGE 328
                 6788888999999999999988888888999**********************99888888888865 PP

  == domain 5  score: -1.1 bits;  conditional E-value: 2
   zf-C2H2_8  32 egklfrcstascaetfpsmqelvaht 57 
                  g+ + c ++ c   f    +l  h 
  EEA21561.1 408 SGRHIACFASDCRYRFYREYDLWVHM 433
                 45555555555555555555555443 PP

>> GAGA  GAGA factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       2.1   2.5e+03      39      44 ..     149     154 ..     138     157 .. 0.80
   2 ?   -1.7   0.0       2.2   2.6e+03      12      30 ..     218     236 ..     209     238 .. 0.74
   3 !   19.4   1.0   5.9e-07    0.0007      16      48 ..     250     282 ..     243     284 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 2.1
                 HHHHHH CS
        GAGA  39 nLRRHL 44 
                  LRRHL
  EEA21561.1 149 RLRRHL 154
                 59***9 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 2.2
                 ----CCCCTTS--EE-TTT CS
        GAGA  12 llkiksksqsEqPAtCPiC 30 
                 l    ++  sE   tC  C
  EEA21561.1 218 LRGHENRVHSESRFTCTEC 236
                 5556789999999999888 PP

  == domain 3  score: 19.4 bits;  conditional E-value: 5.9e-07
                 CCCCTTS--EE-TTT--EESSHHHHHHHHHHHT CS
        GAGA  16 ksksqsEqPAtCPiCqAviRqsRnLRRHLELRH 48 
                 + + +s  P  CP C      sR LRRHLE+ H
  EEA21561.1 250 QAHIKSVHPPECPHCSFQCETSRELRRHLEISH 282
                 556678899*********************999 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0     0.018        21       7      24 ..      79      96 ..      79      97 .. 0.91
   2 ?    4.0   1.1     0.052        62       7      23 ..     109     125 ..     107     127 .. 0.94
   3 ?    4.4   0.0      0.04        48       6      21 ..     170     185 ..     169     190 .. 0.92
   4 ?   -3.0   0.0       8.7     1e+04      11      22 ..     212     223 ..     211     223 .. 0.65
   5 ?    1.0   0.7      0.47   5.6e+02      11      23 ..     243     255 ..     230     257 .. 0.78
   6 !    7.4   0.1    0.0045       5.4       3      21 ..     260     278 ..     258     279 .. 0.93
   7 ?   -2.8   0.0       7.4   8.8e+03       7      22 ..     300     315 ..     300     316 .. 0.86
   8 !    6.6   0.0    0.0085        10       6      23 ..     345     362 ..     344     364 .. 0.93
   9 ?   -0.2   0.0       1.1   1.3e+03       7      24 ..     419     436 ..     418     436 .. 0.88
  10 ?   -1.5   0.0       2.8   3.3e+03      14      23 ..     450     459 ..     449     460 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.018
                 TTBBBSSHHHHHCCTTSH CS
  zf-C2H2_jaz  7 CdKyFksenaldnHlkSK 24
                 C K F+    l++Hl+S+
   EEA21561.1 79 CTKAFNRPARLQEHLRSH 96
                 7799*************8 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.052
                  TTBBBSSHHHHHCCTTS CS
  zf-C2H2_jaz   7 CdKyFksenaldnHlkS 23 
                  CdK+F   + l  H+kS
   EEA21561.1 109 CDKTFLRVSHLNHHIKS 125
                  ***************99 PP

  == domain 3  score: 4.4 bits;  conditional E-value: 0.04
                  TTTBBBSSHHHHHCCT CS
  zf-C2H2_jaz   6 lCdKyFksenaldnHl 21 
                   C+ +F ++ +l +H+
   EEA21561.1 170 PCNETFRKHATLAQHI 185
                  5**************8 PP

  == domain 4  score: -3.0 bits;  conditional E-value: 8.7
                  BSSHHHHHCCTT CS
  zf-C2H2_jaz  11 FksenaldnHlk 22 
                  F ++  l+ H++
   EEA21561.1 212 FDTAAHLRGHEN 223
                  566666777765 PP

  == domain 5  score: 1.0 bits;  conditional E-value: 0.47
                  BSSHHHHHCCTTS CS
  zf-C2H2_jaz  11 FksenaldnHlkS 23 
                  F s   l++H+kS
   EEA21561.1 243 FASYAELQAHIKS 255
                  66667899***99 PP

  == domain 6  score: 7.4 bits;  conditional E-value: 0.0045
                  BBTTTTBBBSSHHHHHCCT CS
  zf-C2H2_jaz   3 YCvlCdKyFksenaldnHl 21 
                  +C++C+ ++++++ l+ Hl
   EEA21561.1 260 ECPHCSFQCETSRELRRHL 278
                  7*****************7 PP

  == domain 7  score: -2.8 bits;  conditional E-value: 7.4
                  TTBBBSSHHHHHCCTT CS
  zf-C2H2_jaz   7 CdKyFksenaldnHlk 22 
                  C + F +  +l  H++
   EEA21561.1 300 CGRSFTKKGNLAVHVR 315
                  9999999999999987 PP

  == domain 8  score: 6.6 bits;  conditional E-value: 0.0085
                  TTTBBBSSHHHHHCCTTS CS
  zf-C2H2_jaz   6 lCdKyFksenaldnHlkS 23 
                  +C K ++s  al++H+++
   EEA21561.1 345 ACGKRYSSKIALEEHVRT 362
                  8**************997 PP

  == domain 9  score: -0.2 bits;  conditional E-value: 1.1
                  TTBBBSSHHHHHCCTTSH CS
  zf-C2H2_jaz   7 CdKyFksenaldnHlkSK 24 
                  C   F  e++l  H++SK
   EEA21561.1 419 CRYRFYREYDLWVHMRSK 436
                  8888999999999****9 PP

  == domain 10  score: -1.5 bits;  conditional E-value: 2.8
                  HHHHHCCTTS CS
  zf-C2H2_jaz  14 enaldnHlkS 23 
                  e+al +H+++
   EEA21561.1 450 ERALLAHENT 459
                  789*****97 PP

>> zf-H2C2_5  C2H2-type zinc-finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0     0.098   1.2e+02       9      20 ..      62      73 ..      62      74 .. 0.94
   2 ?    1.7   0.2      0.18   2.2e+02      13      25 ..      86      97 ..      84      98 .. 0.84
   3 ?   -1.7   1.5       2.2   2.6e+03      15      25 ..     118     128 ..     116     129 .. 0.86
   4 ?    2.9   0.1      0.08        95      16      26 .]     150     159 ..     145     159 .. 0.87
   5 ?   -2.7   0.4       4.6   5.5e+03      14      24 ..     179     189 ..     178     190 .. 0.83
   6 ?   -0.7   0.0       1.1   1.3e+03      15      24 ..     248     257 ..     244     259 .. 0.86
   7 !   19.0   1.0   7.4e-07   0.00089       3      21 ..     261     279 ..     260     283 .. 0.92
   8 !    7.2   0.2    0.0036       4.3      12      26 .]     306     320 ..     305     320 .. 0.91
   9 ?    5.1   0.1     0.016        19      13      24 ..     353     364 ..     351     366 .. 0.82
  10 ?   -0.9   0.2       1.2   1.4e+03      19      24 ..     432     437 ..     429     438 .. 0.91

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.098
   zf-H2C2_5  9 stawksnLkRHl 20
                s++++s+Lk Hl
  EEA21561.1 62 SSKYPSELKTHL 73
                89*********8 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.18
   zf-H2C2_5 13 ksnLkRHlrrkHt 25
                ++ L++Hlr  H+
  EEA21561.1 86 PARLQEHLR-SHN 97
                6789*****.998 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 2.2
   zf-H2C2_5  15 nLkRHlrrkHt 25 
                  L++H++  Ht
  EEA21561.1 118 HLNHHIKSAHT 128
                 699****9997 PP

  == domain 4  score: 2.9 bits;  conditional E-value: 0.08
   zf-H2C2_5  16 LkRHlrrkHtg 26 
                 L+RHl+  H+g
  EEA21561.1 150 LRRHLA-AHDG 159
                 9*****.9987 PP

  == domain 5  score: -2.7 bits;  conditional E-value: 4.6
   zf-H2C2_5  14 snLkRHlrrkH 24 
                 ++L +H+  +H
  EEA21561.1 179 ATLAQHIMSIH 189
                 5899**98777 PP

  == domain 6  score: -0.7 bits;  conditional E-value: 1.1
   zf-H2C2_5  15 nLkRHlrrkH 24 
                 +L+ H++ +H
  EEA21561.1 248 ELQAHIKSVH 257
                 7999***999 PP

  == domain 7  score: 19.0 bits;  conditional E-value: 7.4e-07
   zf-H2C2_5   3 CsqCDYstawksnLkRHlr 21 
                 C++C++   ++++L+RHl+
  EEA21561.1 261 CPHCSFQCETSRELRRHLE 279
                 ******************8 PP

  == domain 8  score: 7.2 bits;  conditional E-value: 0.0036
   zf-H2C2_5  12 wksnLkRHlrrkHtg 26 
                  k+nL  H+r++H+g
  EEA21561.1 306 KKGNLAVHVRTVHEG 320
                 699**********97 PP

  == domain 9  score: 5.1 bits;  conditional E-value: 0.016
   zf-H2C2_5  13 ksnLkRHlrrkH 24 
                 k  L++H+r++H
  EEA21561.1 353 KIALEEHVRTTH 364
                 6679******** PP

  == domain 10  score: -0.9 bits;  conditional E-value: 1.2
   zf-H2C2_5  19 HlrrkH 24 
                 H+r kH
  EEA21561.1 432 HMRSKH 437
                 *****9 PP

>> zf-C2H2_3rep  Zinc finger C2H2-type, 3 repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   1.7       1.4   1.6e+03      37      98 ..     108     129 ..      79     165 .. 0.58
   2 ?    6.3   4.5     0.012        14      37     120 ..     170     252 ..     142     257 .. 0.70
   3 ?    5.4   2.0     0.023        28      29      63 ..     230     264 ..     208     279 .. 0.69
   4 ?    8.5   0.4    0.0026       3.1      13      62 ..     273     324 ..     261     344 .. 0.77
   5 ?    4.9   0.2     0.033        39      38     104 ..     346     414 ..     342     437 .. 0.58
   6 ?    2.7   0.0      0.17     2e+02      37      62 ..     418     443 ..     407     462 .. 0.79

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 1.4
  zf-C2H2_3rep  37 pcgshfgnaeelwlhvlsvhpsdfklskvaqkknlsasedssqklelsksasvennsenesg 98 
                    c   f    +l  h+ s+h+                                        +
    EEA21561.1 108 NCDKTFLRVSHLNHHIKSAHT----------------------------------------A 129
                   344444444444444444444........................................3 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.012
  zf-C2H2_3rep  37 pcgshfgnaeelwlhvlsvhpsdfklskvaqkknlsasedssqklelsksasvennsenesgvrkfvcrfc...GlkfdllpdlGrh 120
                   pc   f ++  l +h++s+h ++       q  n +++++ sq  +++  a ++ ++++++++ +f+c  c    l f    +l  h
    EEA21561.1 170 PCNETFRKHATLAQHIMSIHLKQKPFP--CQYINPTTGQKCSQAFDTA--AHLRGHENRVHSESRFTCTECmssDLSFASYAELQAH 252
                   9*******************8754333..3335666777666665554..5577788888899999998883334556555555555 PP

  == domain 3  score: 5.4 bits;  conditional E-value: 0.023
  zf-C2H2_3rep  29 qclllqcipcgshfgnaeelwlhvlsvhpsdfkls 63 
                   +    +c+     f++  el +h+ svhp ++ + 
    EEA21561.1 230 RFTCTECMSSDLSFASYAELQAHIKSVHPPECPHC 264
                   2333456666668****************998655 PP

  == domain 4  score: 8.5 bits;  conditional E-value: 0.0026
  zf-C2H2_3rep  13 vlethvqerhhvqfveqclllqc.ip.cgshfgnaeelwlhvlsvhpsdfkl 62 
                    l  h++  h   ++e+   + c +p cg  f+++ +l  hv +vh  + + 
    EEA21561.1 273 ELRRHLEISHGDVSLEERRQFSCtVPgCGRSFTKKGNLAVHVRTVHEGEKRF 324
                   567788888877777777778884456*******************988765 PP

  == domain 5  score: 4.9 bits;  conditional E-value: 0.033
  zf-C2H2_3rep  38 cgshfgnaeelwlhvlsvhpsdfklskvaqkknls.asedssqklelsksasve..nnsenesgvrkfvc 104
                   cg  ++++  l  hv + h   +++sk++q+++l  ++e s++k++++ sa+     +    ++ r+  c
    EEA21561.1 346 CGKRYSSKIALEEHVRTTHLG-LMNSKAEQRERLGiKKEPSKRKTNNNVSAMTLltGEGYADESGRHIAC 414
                   9999999999*******9975.556666666655504555555555544443322133334444444445 PP

  == domain 6  score: 2.7 bits;  conditional E-value: 0.17
  zf-C2H2_3rep  37 pcgshfgnaeelwlhvlsvhpsdfkl 62 
                    c+  f  + +lw h+ s h  + + 
    EEA21561.1 418 DCRYRFYREYDLWVHMRSKHGYEERD 443
                   59999***************987765 PP

>> zf-C2H2_11  zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.1       0.4   4.7e+02      10      24 ..     140     154 ..     139     155 .. 0.87
   2 ?    0.6   0.3      0.42     5e+02       7      28 ..     233     257 ..     228     257 .. 0.68
   3 ?    4.0   1.2     0.035        41      19      28 ..     273     282 ..     259     282 .. 0.75
   4 ?    7.0   0.1     0.004       4.8      10      28 ..     300     318 ..     294     319 .. 0.95
   5 ?   11.7   0.0   0.00014      0.16      10      28 ..     346     364 ..     344     364 .. 0.95
   6 ?   -2.9   0.3         5   5.9e+03      13      17 ..     414     418 ..     413     419 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.4
  zf-C2H2_11  10 CGlcftSqlsLsRHl 24 
                 CG  f     L+RHl
  EEA21561.1 140 CGKAFVTGTRLRRHL 154
                 8888999999****8 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.42
  zf-C2H2_11   7 CleC...GlcftSqlsLsRHlfIvH 28 
                 C+eC    l f+S   L+ H   vH
  EEA21561.1 233 CTECmssDLSFASYAELQAHIKSVH 257
                 6666444578888888888877776 PP

  == domain 3  score: 4.0 bits;  conditional E-value: 0.035
  zf-C2H2_11  19 sLsRHlfIvH 28 
                  L+RHl I H
  EEA21561.1 273 ELRRHLEISH 282
                 59*******9 PP

  == domain 4  score: 7.0 bits;  conditional E-value: 0.004
  zf-C2H2_11  10 CGlcftSqlsLsRHlfIvH 28 
                 CG+ ft ++ L  H + vH
  EEA21561.1 300 CGRSFTKKGNLAVHVRTVH 318
                 ******************9 PP

  == domain 5  score: 11.7 bits;  conditional E-value: 0.00014
  zf-C2H2_11  10 CGlcftSqlsLsRHlfIvH 28 
                 CG  ++S+++L  H + +H
  EEA21561.1 346 CGKRYSSKIALEEHVRTTH 364
                 ***************9999 PP

  == domain 6  score: -2.9 bits;  conditional E-value: 5
  zf-C2H2_11  13 cftSq 17 
                 cf+S+
  EEA21561.1 414 CFASD 418
                 ***97 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.1     0.028        33       6      23 ..      79      96 ..      78      98 .. 0.93
   2 ?   -0.4   0.3       1.5   1.8e+03       6      22 ..     109     125 ..     109     126 .. 0.83
   3 ?    2.5   0.0      0.17     2e+02       6      20 ..     171     185 ..     169     187 .. 0.90
   4 ?   -2.5   0.0       6.7     8e+03      18      23 ..     216     221 ..     212     221 .. 0.85
   5 ?   -2.8   0.1       8.1   9.7e+03      11      22 ..     244     255 ..     241     255 .. 0.74
   6 ?   -2.8   0.7       8.2   9.8e+03       3      19 ..     261     277 ..     260     279 .. 0.60
   7 ?    0.5   0.0      0.77   9.2e+02       6      20 ..     300     314 ..     299     316 .. 0.91
   8 ?    4.7   0.0     0.036        43       5      21 ..     345     361 ..     344     362 .. 0.91
   9 ?    6.4   0.0      0.01        12       6      23 ..     419     436 ..     417     437 .. 0.95

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.028
      zf-met  6 CnvtfnsesqlksHlqGK 23
                C + fn ++ l+ Hl+++
  EEA21561.1 79 CTKAFNRPARLQEHLRSH 96
                8899************97 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 1.5
      zf-met   6 CnvtfnsesqlksHlqG 22 
                 C++tf   s+l+ H ++
  EEA21561.1 109 CDKTFLRVSHLNHHIKS 125
                 99999888888888776 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.17
      zf-met   6 CnvtfnsesqlksHl 20 
                 Cn tf   ++l +H 
  EEA21561.1 171 CNETFRKHATLAQHI 185
                 **************7 PP

  == domain 4  score: -2.5 bits;  conditional E-value: 6.7
      zf-met  18 sHlqGK 23 
                 +Hl+G+
  EEA21561.1 216 AHLRGH 221
                 8**996 PP

  == domain 5  score: -2.8 bits;  conditional E-value: 8.1
      zf-met  11 nsesqlksHlqG 22 
                  s + l++H ++
  EEA21561.1 244 ASYAELQAHIKS 255
                 5556799**987 PP

  == domain 6  score: -2.8 bits;  conditional E-value: 8.2
      zf-met   3 CelCnvtfnsesqlksH 19 
                 C+ C  ++     l+ H
  EEA21561.1 261 CPHCSFQCETSRELRRH 277
                 67776666555555666 PP

  == domain 7  score: 0.5 bits;  conditional E-value: 0.77
      zf-met   6 CnvtfnsesqlksHl 20 
                 C ++f+ +++l  H 
  EEA21561.1 300 CGRSFTKKGNLAVHV 314
                 99*********9996 PP

  == domain 8  score: 4.7 bits;  conditional E-value: 0.036
      zf-met   5 lCnvtfnsesqlksHlq 21 
                 +C ++++s+ +l+ H +
  EEA21561.1 345 ACGKRYSSKIALEEHVR 361
                 8**************75 PP

  == domain 9  score: 6.4 bits;  conditional E-value: 0.01
      zf-met   6 CnvtfnsesqlksHlqGK 23 
                 C  +f+ e +l  H+++K
  EEA21561.1 419 CRYRFYREYDLWVHMRSK 436
                 999**************9 PP

>> zf-C2H2_6  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.56   6.7e+02       7      24 ..      79      96 ..      77      98 .. 0.79
   2 ?   -2.3   1.1       4.2   5.1e+03       7      12 ..     109     114 ..     102     128 .. 0.69
   3 ?    9.7   0.0   0.00072      0.86       7      24 ..     140     157 ..     133     159 .. 0.93
   4 ?   -1.8   0.4       2.9   3.5e+03       7      12 ..     171     176 ..     163     177 .. 0.68
   5 ?   -1.0   0.2       1.6   1.9e+03       6      23 ..     207     224 ..     206     228 .. 0.73
   6 ?    6.2   0.2     0.009        11       2      25 ..     231     257 ..     230     260 .. 0.84
   7 ?   -3.1   0.4       7.5   8.9e+03       4      21 ..     261     278 ..     260     282 .. 0.49
   8 ?   -1.8   0.1       2.9   3.4e+03       7      13 ..     300     306 ..     295     319 .. 0.78
   9 ?    5.4   0.0     0.015        18       7      24 ..     346     364 ..     344     366 .. 0.86
  10 ?   -1.6   0.2       2.4   2.9e+03      11      25 ..     423     437 ..     419     438 .. 0.73

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.56
   zf-C2H2_6  7 CsksFpslqaLggHkksH 24
                C k F+    L +H++sH
  EEA21561.1 79 CTKAFNRPARLQEHLRSH 96
                6677777677899****9 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 4.2
   zf-C2H2_6   7 CsksFp 12 
                 C+k+F 
  EEA21561.1 109 CDKTFL 114
                 999995 PP

  == domain 3  score: 9.7 bits;  conditional E-value: 0.00072
   zf-C2H2_6   7 CsksFpslqaLggHkksH 24 
                 C+k F +++ L+ H++ H
  EEA21561.1 140 CGKAFVTGTRLRRHLAAH 157
                 ****************99 PP

  == domain 4  score: -1.8 bits;  conditional E-value: 2.9
   zf-C2H2_6   7 CsksFp 12 
                 C+++F+
  EEA21561.1 171 CNETFR 176
                 999997 PP

  == domain 5  score: -1.0 bits;  conditional E-value: 1.6
   zf-C2H2_6   6 vCsksFpslqaLggHkks 23 
                  Cs  F +   L+gH  +
  EEA21561.1 207 KCSQAFDTAAHLRGHENR 224
                 588888888889999755 PP

  == domain 6  score: 6.2 bits;  conditional E-value: 0.009
   zf-C2H2_6   2 heCsvC...sksFpslqaLggHkksHr 25 
                 + C++C   + sF s+ +L  H ks +
  EEA21561.1 231 FTCTECmssDLSFASYAELQAHIKSVH 257
                 889999777899**********99954 PP

  == domain 7  score: -3.1 bits;  conditional E-value: 7.5
   zf-C2H2_6   4 CsvCsksFpslqaLggHk 21 
                 C+ Cs + ++  +L+ H+
  EEA21561.1 261 CPHCSFQCETSRELRRHL 278
                 666664433444555565 PP

  == domain 8  score: -1.8 bits;  conditional E-value: 2.9
   zf-C2H2_6   7 CsksFps 13 
                 C++sF +
  EEA21561.1 300 CGRSFTK 306
                 9****76 PP

  == domain 9  score: 5.4 bits;  conditional E-value: 0.015
   zf-C2H2_6   7 CsksFpslqaLggHkks.H 24 
                 C+k+++s  aL++H ++ H
  EEA21561.1 346 CGKRYSSKIALEEHVRTtH 364
                 **************86657 PP

  == domain 10  score: -1.6 bits;  conditional E-value: 2.4
   zf-C2H2_6  11 FpslqaLggHkksHr 25 
                 F   ++L  H++s +
  EEA21561.1 423 FYREYDLWVHMRSKH 437
                 666677888**9966 PP

>> zf-C2H2_9  C2H2 type zinc-finger (1 copy)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0       0.2   2.3e+02       3      26 ..      73      98 ..      71     101 .. 0.83
   2 ?    4.6   0.2     0.023        28       5      27 ..     169     191 ..     165     202 .. 0.87
   3 ?   -1.1   0.2       1.4   1.7e+03       4      22 ..     236     254 ..     232     257 .. 0.76
   4 ?    6.6   0.3    0.0058         7       2      23 ..     259     281 ..     258     288 .. 0.86
   5 ?   -2.5   0.0       4.1     5e+03       5      21 ..     298     314 ..     295     320 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.2
                B-TT..T--B-SSHHHHHHHHHHHTS CS
   zf-C2H2_9  3 lCPv..CevkfnswkdlseHilsaas 26
                lCP   C+  fn  ++l eH+ s+++
  EEA21561.1 73 LCPFdgCTKAFNRPARLQEHLRSHNN 98
                799666***************77665 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.023
                 TTT--B-SSHHHHHHHHHHHTSS CS
   zf-C2H2_9   5 PvCevkfnswkdlseHilsaask 27 
                 P C+  f++ ++l++Hi+s   k
  EEA21561.1 169 PPCNETFRKHATLAQHIMSIHLK 191
                 88***************987766 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 1.4
                 -TTT--B-SSHHHHHHHHH CS
   zf-C2H2_9   4 CPvCevkfnswkdlseHil 22 
                 C +  ++f s+++l +Hi 
  EEA21561.1 236 CMSSDLSFASYAELQAHIK 254
                 555667899********95 PP

  == domain 4  score: 6.6 bits;  conditional E-value: 0.0058
                 -B-TTT--B-SSHHHHHHHH.HH CS
   zf-C2H2_9   2 plCPvCevkfnswkdlseHi.ls 23 
                 p CP C  + ++ ++l  H+ +s
  EEA21561.1 259 PECPHCSFQCETSRELRRHLeIS 281
                 67*****************9665 PP

  == domain 5  score: -2.5 bits;  conditional E-value: 4.1
                 TTT--B-SSHHHHHHHH CS
   zf-C2H2_9   5 PvCevkfnswkdlseHi 21 
                 P C  +f +  +l+ H+
  EEA21561.1 298 PGCGRSFTKKGNLAVHV 314
                 889999999999*9998 PP

>> Ogr_Delta  Ogr/Delta-like zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.7     0.031        37      19      46 ..      95     122 ..      86     123 .. 0.79
   2 ?    5.9   0.0     0.011        13      17      41 ..     124     148 ..     119     154 .. 0.86
   3 ?    3.3   4.7     0.067        80       1      38 [.     260     305 ..     260     310 .. 0.88
   4 ?   -3.0   0.2       6.5   7.7e+03      27      38 ..     413     424 ..     407     426 .. 0.80

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.031
   Ogr_Delta  19 kdvreryyqCsnfeCgatfvaaeeiert 46 
                  +  er++ C+ ++C  tf +  + ++ 
  EEA21561.1  95 SHNNERIFHCTYDNCDKTFLRVSHLNHH 122
                 45568**************998888776 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.011
   Ogr_Delta  17 lskdvreryyqCsnfeCgatfvaae 41 
                 +s++++ r y C+ + Cg  fv+  
  EEA21561.1 124 KSAHTAVRDYICDRPGCGKAFVTGT 148
                 6889999**************9965 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.067
   Ogr_Delta   1 rCPhCgapaaartsrnlskdvre........ryyqCsnfeCgatfv 38 
                 +CPhC     +++  + +             r ++C+++ Cg +f+
  EEA21561.1 260 ECPHCSFQCETSRELRRHLEISHgdvsleerRQFSCTVPGCGRSFT 305
                 6*****9999999888888888889999999***********9986 PP

  == domain 4  score: -3.0 bits;  conditional E-value: 6.5
   Ogr_Delta  27 qCsnfeCgatfv 38 
                  C   +C ++f 
  EEA21561.1 413 ACFASDCRYRFY 424
                 688899*99996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (560 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       545  (0.0303977); expected 358.6 (0.02)
Passed bias filter:                      316  (0.0176251); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.59u 0.25s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 3661.94
//
Query:       EEA21562.1  [L=141]
Description: DNA-directed RNA polymerase I, II, and III subunit Rpb6 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.9e-15   55.5   0.0    6.1e-15   54.9   0.0    1.3  1  RNA_pol_Rpb6  RNA polymerase Rpb6


Domain annotation for each model (and alignments):
>> RNA_pol_Rpb6  RNA polymerase Rpb6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.9   0.0   3.4e-19   6.1e-15       3      46 ..      91     139 ..      89     140 .. 0.94

  Alignments for each domain:
  == domain 1  score: 54.9 bits;  conditional E-value: 3.4e-19
                   TTSS--HHHHHHHHHHHHHHH....HT........S.S-SSSSTTCHHHHTT- CS
  RNA_pol_Rpb6   3 tskvltrYelvriaakRArQieegesl........e.tqkpvviAlrEiaegk 46 
                   t++++t+Ye +r++++RA+Qi    s+        e +++p++iAl+E+ ++k
    EEA21562.1  91 TTPYMTKYERARVLGTRALQI----SMnapvlvdlEgETDPLQIALKELNQKK 139
                   89*******************....99999999997789***********998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (141 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       271  (0.0151152); expected 358.6 (0.02)
Passed bias filter:                      216  (0.0120475); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.27s 00:00:00.67 Elapsed: 00:00:00.43
# Mc/sec: 981.68
//
Query:       EEA21563.1  [L=440]
Description: COPII-coated vesicle membrane protein Erv46, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.6e-85  284.4   0.0    8.8e-85  284.0   0.0    1.2  1  COPIIcoated_ERV  Endoplasmic reticulum vesicle transporter
    2.1e-31  108.1   0.0    4.7e-30  103.8   0.0    2.3  2  ERGIC_N          Endoplasmic Reticulum-Golgi Intermediate Com


Domain annotation for each model (and alignments):
>> COPIIcoated_ERV  Endoplasmic reticulum vesicle transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  284.0   0.0   9.8e-89   8.8e-85       1     221 []     143     422 ..     143     422 .. 0.95

  Alignments for each domain:
  == domain 1  score: 284.0 bits;  conditional E-value: 9.8e-89
  COPIIcoated_ERV   1 CYgaeeee.....kCCntCedVreaYkkkgwafkdgeeieqCeregykeklkeqkkegCrikGklevnkvaGnfhiapgksfqeekrhvhdlss 89 
                      C ga+++e     +CCntCe+VreaY+ k+waf +ge+ieqC+regy++++++q++egCri+G+++vnkv Gnfhiapg+sf+++++hvhdl++
       EEA21563.1 143 CGGASPPEnakkpGCCNTCEEVREAYALKSWAFGKGENIEQCQREGYADRIDAQRREGCRIEGDIRVNKVIGNFHIAPGRSFSSGNMHVHDLDT 236
                      6677777777788*******************************************************************************99 PP

  COPIIcoated_ERV  90 yek.e.....klnfsHtihkLsfgeelpgek...........knPLdgtkkeeeekalmfqYflkvvptkyekldkkk................ 150
                      y + e     k+++sH+ih+L+fg++l++e            +nPLd+t++ ++e a++++Y++kvv+t+y +l++++                
       EEA21563.1 237 YLDrEladyeKHTMSHIIHQLRFGPQLSDEVsqrwqwtdhhhTNPLDSTQQLTNEPAYNYNYYIKVVSTSYLPLGWDSarsdqlhgddqftplg 330
                      9954234466******************9999*********99*******99**********************99777899************ PP

  COPIIcoated_ERV 151 ...........ietnqysvtehersleggkde.........sekglPGvffsYeisPlkvivkeerk.sflhfltslcaiiGGvltvasliD 221
                                 iet+qysvt+h+rsl+gg+d+         +e+g+PGvff+Y+isP+kv+++e r+ +f++flt++ca+iGG+ltva+++D
       EEA21563.1 331 lhgaahgtagsIETHQYSVTSHKRSLHGGNDAaeghqerihAEGGIPGVFFNYDISPMKVVNREARAkTFTGFLTGVCAVIGGTLTVAAAVD 422
                      *****************************999*********99***********************99**********************99 PP

>> ERGIC_N  Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.8   0.0   5.2e-34   4.7e-30       1      90 [.       7      96 ..       7      97 .. 0.98
   2 ?    1.7   0.0     0.036   3.3e+02      10      40 ..     391     421 ..     382     431 .. 0.68

  Alignments for each domain:
  == domain 1  score: 103.8 bits;  conditional E-value: 5.2e-34
                XXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXX-EEEEEE--S--SEEEEEEEEEE.SS-GGGEEEEEEETTECEE CS
     ERGIC_N  1 lrrfDafpKvpedltqktlsGgiislvcillilfLllselteylttevkeelvvdksrsekleinlditfpalpCellsldvqDesgehe 90
                + r+Daf+K+ ed +++t+sGgi++lv++++il+L++ e+++y+++ v +el+vdksr+e++ei+l++tfp+lpCell+ldv+D+sge++
  EEA21563.1  7 FTRLDAFAKTVEDARVRTTSGGIVTLVSLVVILWLVWGEWADYRRVVVLPELIVDKSRGERMEIHLNMTFPRLPCELLTLDVMDVSGEQQ 96
                579*************************************************************************************98 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.036
                 XXXXX.XXXXXXXXXXXXXXXXXXXXXXXXX CS
     ERGIC_N  10 vpedltqktlsGgiislvcillilfLllsel 40 
                 v+++ + kt++G +  +++++  ++ + + +
  EEA21563.1 391 VNREARAKTFTGFLTGVCAVIGGTLTVAAAV 421
                 5778877999988777777665555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (440 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       465  (0.0259356); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.47
# Mc/sec: 2819.99
//
Query:       EEA21564.1  [L=644]
Description: mRNA export factor mex67 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.9e-15   55.6   0.5    5.6e-15   54.7   0.5    1.5  1  TAP_C      TAP C-terminal domain
    4.9e-07   30.0  11.0    0.00024   21.4   8.2    2.8  2  LRR_4      Leucine Rich repeats (2 copies)
    1.1e-06   28.2   3.2    2.9e-06   26.9   3.2    1.8  1  LRR_8      Leucine rich repeat
    2.1e-06   27.4   0.1    4.1e-06   26.4   0.1    1.4  1  LRR_9      Leucine-rich repeat
    9.3e-05   23.0   0.0    0.00052   20.6   0.0    2.3  1  NTF2       Nuclear transport factor 2 (NTF2) domain
     0.0009   19.0   0.0     0.0023   17.7   0.0    1.7  1  RRM_9      RNA recognition motif
  ------ inclusion threshold ------
      0.032   14.3   0.1      0.032   14.3   0.1    2.7  3  LRR_6      Leucine Rich repeat
       0.13   12.9   5.3          7    7.6   0.2    3.7  3  LRR_1      Leucine Rich Repeat
       0.35   10.9   1.6        1.3    9.2   0.9    2.4  2  EF-hand_6  EF-hand domain


Domain annotation for each model (and alignments):
>> TAP_C  TAP C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.7   0.5   2.8e-18   5.6e-15       1      49 []     591     639 ..     591     639 .. 0.99

  Alignments for each domain:
  == domain 1  score: 54.7 bits;  conditional E-value: 2.8e-18
                 HHHHHHHHHH-B-HHHHHHHHSSTTT-HHHHHHHHHHHG..GGS-GGGB CS
       TAP_C   1 emvqafstqtgMnlewsqkcLeqnnWdyerAlqvFeelkakgkIPpeAF 49 
                 ++v ++s  t+++le+sq+ L q nW +e Al +Fee+ka+++IP+eAF
  EEA21564.1 591 QLVLQLSFATQLKLEFSQRALVQHNWSIEGALRAFEESKAQNQIPAEAF 639
                 89**********************************************9 PP

>> LRR_4  Leucine Rich repeats (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   8.2   1.2e-07   0.00024       4      38 ..     255     292 ..     252     298 .. 0.80
   2 !    7.9   0.0    0.0021       4.2       2      29 ..     305     337 ..     304     344 .. 0.89

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 1.2e-07
                 -EEE--SS---E-S-...HH.H-TT--EEE-.-S----- CS
       LRR_4   4 evLdLsnNqltdipl...le.klpnLkeLdLsgNnlitd 38 
                 e+L+L+nN lt i++   l+ ++pnLk LdLs+N +i+d
  EEA21564.1 255 ENLSLANNGLTNINPittLSqNFPNLKALDLSNN-NIQD 292
                 89*************7775546*********555.7766 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0021
                 S--EEE--SS---E-S-HH....H.-TT--EEE CS
       LRR_4   2 nLevLdLsnNqltdiplle....k.lpnLkeLd 29 
                 +Le++dL nN  +++++++    k  p+Lk+L+
  EEA21564.1 305 QLEFIDLTNNPFSSLGSFKdtmmKwYPKLKTLN 337
                 69***************9999998899999996 PP

>> LRR_8  Leucine rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.9   3.2   1.5e-09   2.9e-06       3      60 ..     254     315 ..     252     316 .. 0.87

  Alignments for each domain:
  == domain 1  score: 26.9 bits;  conditional E-value: 1.5e-09
                 -SEEE-TTS--SEE-TTSSTT..-TT--EEE--SS---G...GGGGGGTT--S-.EEE--SS- CS
       LRR_8   3 LtsLdLsnNrltslddeaFkg..lsnLkvLdLsnNlltt...lspgafsgLpsLrsLdLsgNr 60 
                 +++L+L nN lt++++ +  +  ++nLk LdLsnN+++    l  ++ + +++L+++dL++N+
  EEA21564.1 254 VENLSLANNGLTNINPITTLSqnFPNLKALDLSNNNIQDekaL-DKWRWKFRQLEFIDLTNNP 315
                 689************98754334**************987745.69****************7 PP

>> LRR_9  Leucine-rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.4   0.1     2e-09   4.1e-06      66     159 ..     254     350 ..     250     353 .. 0.91

  Alignments for each domain:
  == domain 1  score: 26.4 bits;  conditional E-value: 2e-09
       LRR_9  66 lktlllnnnrivriae..gleevlPnleelvltnnelqeladldPl.aslkklellsllknpvtnkkeyrlyviyklkqlrlldfrkvklkereeae 159
                 ++ l+l+nn +++i++   l++  Pnl++l l+nn++q+   ld    ++++le++ l +np ++   ++  ++   ++l+ l+  +v+++e  +a+
  EEA21564.1 254 VENLSLANNGLTNINPitTLSQNFPNLKALDLSNNNIQDEKALDKWrWKFRQLEFIDLTNNPFSSLGSFKDTMMKWYPKLKTLNNIQVRTDEEVAAQ 350
                 56799*********975589***********************986369****************************************99977775 PP

>> NTF2  Nuclear transport factor 2 (NTF2) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.6   0.0   2.6e-07   0.00052       2     118 ..     369     539 ..     368     541 .. 0.87

  Alignments for each domain:
  == domain 1  score: 20.6 bits;  conditional E-value: 2.6e-07
                 HHHHHHHHHHHHHHHGGGGGGGGEEEEEEEEEETTE.......................................EEEESHHHHHHHHHHSSCSC.... CS
        NTF2   2 akafvqqYYaaldagdregllalyaadaslltpegs.......................................spvkgreaIteffrslpftr.... 57 
                 a+ f+++++  +d+ dr+g l+ly++++s  +++ +                                       +  +g+e+I++  ++ p+t+    
  EEA21564.1 369 AETFIRNFFLGFDK-DRNGTLNLYYDNNSSFSYNVNpvaprsaqdvtttpapgwdswikgsrnlkkihhlaarmsRMYVGIEKIRDIWNTMPQTQhpgl 466
                 789***********.**********999999999999**************************************999****************87777 PP

                 .......E.EEEEEEEEEEE......TSEGGGCEEEEEEEEEEEETTSCCE..EEEEEEEEEEEET.TTEEEEEEEEE CS
        NTF2  58 .......i.elkittvdaqp......deaslstgvlvmvtGelkvddfkkr..rkfsqtfilapqs.nkgyfvlnDif 118
                        i  + i             +++s  +g l+ + G++ +  ++k   r+f +tfil p+    + +v +D++
  EEA21564.1 467 dqpaqwlIeCHLIP-----ClpdatgQSPSGVGGFLITIHGQFDESSGGKVetRSFDRTFILGPSPgPENVKVISDML 539
                 77744443233333.....1446657999999************999987799***********98777778888876 PP

>> RRM_9  RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0   1.2e-06    0.0023      27      69 ..     135     176 ..     127     177 .. 0.88

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 1.2e-06
       RRM_9  27 alqnasveggvlvgyVktkkdaeeLlkwnGvrFAGnnLkieil 69 
                 ++ + +veg++lv +V  ++ ++++ ++nG+ FAG +L +e+ 
  EEA21564.1 135 NIIKHRVEGDTLVVTV-RPELVDRMSQINGFTFAGAELTVEKY 176
                 567789**********.5699******************9986 PP

>> LRR_6  Leucine Rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.3       1.9   3.7e+03       6      17 ..     255     266 ..     254     266 .. 0.83
   2 ?   14.3   0.1   1.6e-05     0.032       3      18 ..     278     293 ..     278     293 .. 0.94
   3 ?   -2.0   0.0       2.7   5.4e+03       5      16 ..     306     317 ..     304     320 .. 0.78

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 1.9
       LRR_6   6 teLdLsgNdIgD 17 
                 + L+L+ N++++
  EEA21564.1 255 ENLSLANNGLTN 266
                 5699****9986 PP

  == domain 2  score: 14.3 bits;  conditional E-value: 1.6e-05
       LRR_6   3 thLteLdLsgNdIgDe 18 
                 ++L++LdLs N+I+De
  EEA21564.1 278 PNLKALDLSNNNIQDE 293
                 58*************8 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 2.7
       LRR_6   5 LteLdLsgNdIg 16 
                 L+  dL+ N ++
  EEA21564.1 306 LEFIDLTNNPFS 317
                 7788*****886 PP

>> LRR_1  Leucine Rich Repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.2       7.6   1.5e+04       5      15 ..     257     267 ..     255     276 .. 0.75
   2 ?    7.6   0.2    0.0035         7       1      12 [.     279     290 ..     279     298 .. 0.86
   3 ?    5.8   0.0     0.014        28       1      16 [.     305     320 ..     305     323 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 7.6
       LRR_1   5 LdLsnnpllgl 15 
                 L L nn l+++
  EEA21564.1 257 LSLANNGLTNI 267
                 88999998654 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0035
       LRR_1   1 nLrhLdLsnnpl 12 
                 nL+ LdLsnn++
  EEA21564.1 279 NLKALDLSNNNI 290
                 8*********98 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.014
       LRR_1   1 nLrhLdLsnnpllglp 16 
                 +L+ +dL+nnp+++l+
  EEA21564.1 305 QLEFIDLTNNPFSSLG 320
                 599********97765 PP

>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       6.1   1.2e+04      17      29 ..      65      76 ..      64      78 .. 0.78
   2 ?    9.2   0.9   0.00065       1.3       2      18 ..     373     389 ..     372     391 .. 0.90

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 6.1
   EF-hand_6 17 idaeElrkalrka 29
                +d++ +rka++ +
  EEA21564.1 65 LDRDRIRKAIS-S 76
                79999999998.5 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00065
   EF-hand_6   2 lreaFklfDkdgdGkid 18 
                 +r +F  fDkd++G+++
  EEA21564.1 373 IRNFFLGFDKDRNGTLN 389
                 799************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (644 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       506  (0.0282224); expected 358.6 (0.02)
Passed bias filter:                      431  (0.0240393); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.70u 0.31s 00:00:01.01 Elapsed: 00:00:00.55
# Mc/sec: 3496.71
//
Query:       EEA21565.1  [L=859]
Description: GARP complex subunit Vps53, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   2.6e-107  359.1   8.7   4.5e-107  358.3   8.7    1.4  1  Vps53_N         Vps53-like, N-terminal
      1e-08   34.8   7.9      1e-08   34.8   7.9    1.6  2  Vps54_N         Vacuolar-sorting protein 54, of GARP complex
    1.9e-06   27.8   0.0    6.9e-06   26.0   0.0    2.0  1  DUF2451         Protein of unknown function C-terminus (DUF24
    3.1e-06   27.3   2.5    3.1e-06   27.3   2.5    2.2  2  COG2            COG (conserved oligomeric Golgi) complex comp
     0.0049   15.5   7.8     0.0098   14.5   7.8    1.4  1  Zw10            Centromere/kinetochore Zw10
  ------ inclusion threshold ------
       0.01   15.7   5.2      0.024   14.5   5.2    1.6  1  Sigma70_ner     Sigma-70, non-essential region
      0.019   15.1   1.8      0.084   13.1   1.8    2.1  1  XhlA            Haemolysin XhlA
      0.047   12.6   9.0      0.086   11.7   9.0    1.4  1  Spc7            Spc7 kinetochore protein
      0.097   12.6   3.8       0.29   11.0   3.8    1.8  1  Sec8_exocyst    Sec8 exocyst complex component specific domai
        0.1   13.5   5.3        4.4    8.2   0.4    3.0  2  DUF5339         Family of unknown function (DUF5339)
       0.12   11.0   2.8       0.21   10.2   2.8    1.3  1  FapA            Flagellar Assembly Protein A
       0.13   12.9   0.1       0.35   11.5   0.1    1.7  1  LtuB            Late transcription unit B
       0.16   12.0   7.6       0.31   11.1   6.2    2.2  2  Baculo_PEP_C    Baculovirus polyhedron envelope protein, PEP,
       0.17   11.4   5.1       0.48   10.0   5.1    1.8  1  Exonuc_VII_L    Exonuclease VII, large subunit
       0.32   11.3   5.2        3.4    8.0   0.9    2.9  2  DUF5082         Domain of unknown function (DUF5082)
       0.34   10.9   4.5        0.7    9.9   3.8    2.0  1  DUF1515         Protein of unknown function (DUF1515)
       0.58   10.5   6.0        1.1    9.6   3.8    2.7  2  BLOC1_2         Biogenesis of lysosome-related organelles com
       0.62   10.6  10.0        1.2    9.7   8.8    2.1  1  APG6_N          Apg6 coiled-coil region
       0.72    8.9  12.3       0.17   11.0   8.6    1.7  2  Atg14           Vacuolar sorting 38 and autophagy-related sub
        1.5    8.9   9.6        0.9    9.6   5.9    2.6  3  BRE1            BRE1 E3 ubiquitin ligase
        1.7    8.8   6.9         18    5.5   6.9    2.5  1  Fib_alpha       Fibrinogen alpha/beta chain family
        1.8    9.0   7.7        4.4    7.7   4.9    3.2  2  Syntaxin_2      Syntaxin-like protein
        1.9    8.5   5.5          2    8.5   3.2    2.3  1  DUF1664         Protein of unknown function (DUF1664)
        5.3    7.7  10.0        2.7    8.7   7.0    2.1  1  HIP1_clath_bdg  Clathrin-binding domain of Huntingtin-interac
        6.2    7.5   5.6        4.2    8.1   1.9    2.6  2  YabA            Initiation control protein YabA
        6.8    6.8  13.1       0.81    9.7   7.2    2.5  2  TPR_MLP1_2      TPR/MLP1/MLP2-like protein
        7.9    7.0   7.2         16    6.1   3.0    3.5  2  NPV_P10         Nucleopolyhedrovirus P10 protein


Domain annotation for each model (and alignments):
>> Vps53_N  Vps53-like, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  358.3   8.7  6.8e-110  4.5e-107       2     377 ..      15     390 ..      14     393 .. 0.95

  Alignments for each domain:
  == domain 1  score: 358.3 bits;  conditional E-value: 6.8e-110
     Vps53_N   2 adfsaleyinellpteqslanidelikklqeeikklddeiksvvraqanvgekgkealeeaqkaieelfqkikeikdkaekseemvkeitrdIkqLDiA 100
                 +d+++++++n ++ +  +l  + ++ + l++  ++ld +i+ +v++q  +  ++ + ++ a++ ++elf+ki +++++a ++e+++ ++t dIkqLD A
  EEA21565.1  15 VDYDPIAHLNSIFSHPSTLSSVSQTSEALRKYENELDTDIARLVEEQVTSNAESVQRIQAAKADLSELFKKIDDVRERASRTEQSITDMTADIKQLDNA 113
                 699************************************************************************************************ PP

     Vps53_N 101 KknlttsiTtlkrLkmLvtavesleallskrsykeivsllqavlqllnhFekYkdvekIaeLsesisklkkslksqiledfkeaFssgsqkeketgnll 199
                 Kknlt s+T+lkrL+mL+ta+e+l+al++ r+y + ++llqav+ql+ hF++Y+++++Ia Ls+++  ++++l +q+ edf+  Fs g+  + +     
  EEA21565.1 114 KKNLTVSMTALKRLQMLTTAYEQLRALAKTRQYRDCAQLLQAVIQLMAHFKSYRSIDQIAALSRNVADVQRELLEQVCEDFEITFSKGEVVQRRVM--- 209
                 *************************************************************************************77776666665... PP

     Vps53_N 200 ekledaCrvvdildpsvkeelikwfiekqLeeykkifreneeaasLdkldrRYawlkrklqdfeekykkiFpadWevaeRltveFckvTrkdlekilkr 298
                   l++aC+v+d+l  + +  l  w+++ qL ey ++fr neea+sLd+++rRY w+kr +++++e +++iFp +W+v+e l+  Fc+ Tr+d + il r
  EEA21565.1 210 --LAEACLVMDALGDNSRSRLTTWYCNTQLREYRQVFRGNEEAGSLDNISRRYSWFKRMMKTYDEEHANIFPSSWRVNEVLANAFCESTRDDFKGILSR 306
                 ..9**********************************************************************************************98 PP

     Vps53_N 299 ...kkkelsvkllllalqsTleFEklldkrFsntiskakkkkekkela..fegaisscFephltlyiesqektlsellekfvse 377
                      + ++v+lll  lq+Tl+FE+ ld+rF++t   +  +      +    + is+ Fep+l +++e+q+k+l  ll k+ ++
  EEA21565.1 307 svrSGQTIDVNLLLSCLQETLDFEHSLDRRFTQTSRASMDTVASSIESpfTIQSISEAFEPYLGVWVEAQDKQLASLLPKYRQQ 390
                 7756799************************87665555555444333656789***********************9998765 PP

>> Vps54_N  Vacuolar-sorting protein 54, of GARP complex
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.8   7.9   1.6e-11     1e-08      12     198 ..      16     197 ..      12     224 .. 0.89
   2 ?   -2.7   0.0       4.2   2.8e+03     220     264 ..     434     478 ..     427     487 .. 0.79

  Alignments for each domain:
  == domain 1  score: 34.8 bits;  conditional E-value: 1.6e-11
     Vps54_N  12 efdpikyeLkklpddelsyesiekevkklksqhdvvskklsqlilekreefvkelseveeiekelkesvvickngrraLdlakkeltrtsLellakskk 110
                 ++dpi + L+++  +   ++s+ ++++ l+++ + ++  +  l+ e+ ++ ++ +++++  + +l e  +++ + r+  + +++ +t +   +    + 
  EEA21565.1  16 DYDPIAH-LNSIFSHPSTLSSVSQTSEALRKYENELDTDIARLVEEQVTSNAESVQRIQAAKADLSELFKKIDDVRERASRTEQSITDMTADIKQLDNA 113
                 6788866.8888888899999************************************************************************999999 PP

     Vps54_N 111 rqllkkllktltaikelrelekrleelleeedysaAiqllletkqlaekysqyncvqelssklqetlelveekldsqLsevckeFdse 198
                 ++ l+  ++ l+ ++ l ++ ++l+ l +  +y    qll  + ql+ +++ y++++++   l  +++ v+ +l   L++vc++F+ +
  EEA21565.1 114 KKNLTVSMTALKRLQMLTTAYEQLRALAKTRQYRDCAQLLQAVIQLMAHFKSYRSIDQIA-ALSRNVADVQREL---LEQVCEDFEIT 197
                 9999988999**********************************************9986.5777777777766...78889999864 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 4.2
     Vps54_N 220 lhsnFvqaiesetkavlkshleleeseeeelkkltYedLCeklke 264
                 l ++F +   + +++vl +++ + + +++ +k  + edL + l+ 
  EEA21565.1 434 LSKVFAKYLDQYAQQVLLHYISERATTQTPSKVPSIEDLILVLNT 478
                 778888999999999999999999888888888888887766665 PP

>> DUF2451  Protein of unknown function C-terminus (DUF2451)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0   0.0     1e-08   6.9e-06      65     173 ..     529     633 ..     412     645 .. 0.80

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 1e-08
     DUF2451  65 rllnleslleaianvkWdvkevatehssYvdqllkeves.fskklqelkerlklpeevkkalweaavevvtetLvegyskvkkcseeGRalMqlDvqql 162
                   ++le +  ++ n  W+  e   ++s+Yv +ll + ++  + +lq+    l+ p +   a+ +++ve++++t++    + + +se G  +M+lD+ +l
  EEA21565.1 529 LEVQLEPCWREMRNFPWNKLENVGDQSPYVGELLSKTKTqAGDILQS----LHKP-QYARAFADNTVEFISNTFITTVYSCRPVSETGAEQMLLDLYTL 622
                 3355589999**********************999998868888888....4334.455799***************999******************* PP

     DUF2451 163 lakleklskik 173
                  + l++l ++ 
  EEA21565.1 623 KSGLTSLLPSP 633
                 ****9998864 PP

>> COG2  COG (conserved oligomeric Golgi) complex component, COG2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   2.5   4.7e-09   3.1e-06      12     132 ..      16     140 ..      11     141 .. 0.89
   2 ?   -1.5   0.1       3.8   2.5e+03      83     126 ..     170     214 ..     156     220 .. 0.61

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 4.7e-09
        COG2  12 dFdpdqFvse.lrhgvpLeslrr...dLeaylkllekellelvnedyadFvslSghLvglqeeleevesplaaarkkvesvreklsereeeveskleea 106
                 d+dp++ +++  +h  +L s+++    L++y+++l++++++lv+e +    +  ++ +  +++l+e+ +++  +r++ + +++++ ++ +++++  +++
  EEA21565.1  16 DYDPIAHLNSiFSHPSTLSSVSQtseALRKYENELDTDIARLVEEQVTSNAESVQRIQAAKADLSELFKKIDDVRERASRTEQSITDMTADIKQLDNAK 114
                 8*********99999998877542228*********************999999999999999999999999999999999999999999999999999 PP

        COG2 107 keleekrellklllkldevvekleal 132
                 k+l+     lk+l++l++  e+l al
  EEA21565.1 115 KNLTVSMTALKRLQMLTTAYEQLRAL 140
                 9999999***********99999876 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 3.8
        COG2  83 kkvesvreklsereeeveskleeakeleekr.ellklllkldevv 126
                 +++ ++ +++++ ++e+ +++ e  e++  + e++++ ++l+e +
  EEA21565.1 170 DQIAALSRNVADVQRELLEQVCEDFEITFSKgEVVQRRVMLAEAC 214
                 455556666666666666666666666655556666666665555 PP

>> Zw10  Centromere/kinetochore Zw10
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   7.8   1.5e-05    0.0098      24     174 ..      48     195 ..      26     199 .. 0.69

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 1.5e-05
        Zw10  24 eeikeevskmivkkYseflelsssaeellerveslskeidalkkkveneieqdlkaaveelaelkqqlkekevvlellealkkieealeelkealknka 122
                 +e+ + +   ++++     e+ +  +     +++l k id++ ++ +   eq + + +  + +l +  k+ +v++  l++l+ + +a e+l+   k+++
  EEA21565.1  48 NELDTDIARLVEEQVTSNAESVQRIQAAKADLSELFKKIDDVRERASR-TEQSITDMTADIKQLDNAKKNLTVSMTALKRLQMLTTAYEQLRALAKTRQ 145
                 444444444444444444555555555556666666666666666443.3445555555555555566777899999********************** PP

        Zw10 123 flvaadlleelkslldlekvekafqlkilkalrkelsvlsenlqykLgeewd 174
                 ++ +a+ll+ + +l++  k+ +   ++ ++al+ +    + +l+++  e+++
  EEA21565.1 146 YRDCAQLLQAVIQLMAHFKSYRS--IDQIAALSRNVADVQRELLEQVCEDFE 195
                 *************9998888854..444569999999999999999888876 PP

>> Sigma70_ner  Sigma-70, non-essential region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   5.2   3.6e-05     0.024      10     129 ..      67     179 ..      30     190 .. 0.75

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 3.6e-05
  Sigma70_ner  10 elydrveageirLrdiidGflDeeeeeeeeeeeedeeeeeeeedddeeeseseaadeeelkeealekfeelreqyeklrkalkkkgr.kskkyekare 106
                  e  +r++a +  L+++ +  +D     +  e ++++e++  +    + ++ ++a+++      al++++ l ++ye+lr++ k+ ++ +++++ +a  
   EEA21565.1  67 ESVQRIQAAKADLSELFK-KID-----DVRERASRTEQSITDMTA-DIKQLDNAKKNLTVSMTALKRLQMLTTAYEQLRALAKTRQYrDCAQLLQAVI 157
                  456778888888888888.444.....222222222222222222.3468999***************************99999777********** PP

  Sigma70_ner 107 elseefkefrLtpkqidrLveql 129
                  +l+++fk+ r +  qi +L +++
   EEA21565.1 158 QLMAHFKSYR-SIDQIAALSRNV 179
                  ********99.445566666655 PP

>> XhlA  Haemolysin XhlA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   1.8   0.00013     0.084       4      46 ..      70     112 ..      67     122 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 0.00013
        XhlA   4 erlerietkldnleervdkleekaaeaeekiknleedlkkles 46 
                 +r++  +++l +l +++d++ e+a+++e++i  ++ d+k+l +
  EEA21565.1  70 QRIQAAKADLSELFKKIDDVRERASRTEQSITDMTADIKQLDN 112
                 788888999999999*************************987 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   9.0   0.00013     0.086     164     259 ..      35     130 ..      31     161 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00013
        Spc7 164 eldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaervlee 259
                  +++  ++l+++++el   +++l e++   ++   +++++++ +l+el ++i+  +++ ++ ++ +++ +++i++l++ k++l   + + +r+++ 
  EEA21565.1  35 SVSQTSEALRKYENELDTDIARLVEEQVTSNAESVQRIQAAKADLSELFKKIDDVRERASRTEQSITDMTADIKQLDNAKKNLTVSMTALKRLQML 130
                 567788999****************999999999*************************************************9999999998875 PP

>> Sec8_exocyst  Sec8 exocyst complex component specific domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   3.8   0.00043      0.29      40     139 ..      38     137 ..      23     140 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00043
  Sec8_exocyst  40 hrlkefkqlkkqieeaLqevvnehhqaFnssiasYskilssiqesqekvselKesleeakkklstkkkeLkelnarsakykevieiLdaieelkkvp 136
                   +  + +++ ++++++++   v+e   + ++s++  + +   ++e  +k+ +++e+ + +++++++  +++k+l +  ++++  +  L+ ++ l++  
    EEA21565.1  38 QTSEALRKYENELDTDIARLVEEQVTSNAESVQRIQAAKADLSELFKKIDDVRERASRTEQSITDMTADIKQLDNAKKNLTVSMTALKRLQMLTTAY 134
                   55667888999999*****************************************************************************999988 PP

  Sec8_exocyst 137 dki 139
                   +++
    EEA21565.1 135 EQL 137
                   876 PP

>> DUF5339  Family of unknown function (DUF5339)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   0.3     0.021        14       7      43 ..      81     117 ..      80     123 .. 0.94
   2 ?    8.2   0.4    0.0066       4.4      33      69 ..     127     163 ..     118     164 .. 0.88

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.021
     DUF5339   7 kYFkevdkliakaekqpgtktqadaikkqleqsKkqi 43 
                 ++Fk++d+  + a++++++ t+++a  kql+ +Kk +
  EEA21565.1  81 ELFKKIDDVRERASRTEQSITDMTADIKQLDNAKKNL 117
                 79********************************987 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.0066
     DUF5339  33 kkqleqsKkqilalpkeqQeaaCkqgldalkqlkqsm 69 
                  ++l ++++q+ al k  Q   C q l+a+ ql++ +
  EEA21565.1 127 LQMLTTAYEQLRALAKTRQYRDCAQLLQAVIQLMAHF 163
                 588999************************9999876 PP

>> FapA  Flagellar Assembly Protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   2.8   0.00032      0.21     333     411 ..      41     117 ..      28     166 .. 0.67

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00032
        FapA 333 pelkeklkeleeeleeleeeleklkkk.ikklpklkaekqlesekkeqlkklletkeklkeeleeleeelkelkeelesk 411
                  +l++  +el++++ +l ee+ + +++ ++++++    k+  se +++++ ++e   + +++++++++++k+l++  ++ 
  EEA21565.1  41 EALRKYENELDTDIARLVEEQVTSNAEsVQRIQA---AKADLSELFKKIDDVRERASRTEQSITDMTADIKQLDNAKKNL 117
                 5666666888888888866666666663444444...5566778888888888888888888888888888888777776 PP

>> LtuB  Late transcription unit B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.1   0.00053      0.35      18      55 ..      32      69 ..      23      75 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00053
        LtuB 18 hysliskekeslrkrakefdvlvrslldkqvsqdadqv 55
                  s +s+  e lrk  +e d+ +  l++ qv+ +a+ v
  EEA21565.1 32 TLSSVSQTSEALRKYENELDTDIARLVEEQVTSNAESV 69
                568899*****************************988 PP

>> Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   6.2   0.00047      0.31      22     122 ..      23     128 ..      18     145 .. 0.86
   2 ?   -2.1   0.0       5.4   3.6e+03      67      67 ..     170     170 ..     126     194 .. 0.43

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00047
  Baculo_PEP_C  22 LnairlqnvqilaqlatlldaietqLnalsedlksllaeldtrldtlltnLtdalnalq......dtlrneLtnlnsiltnLlssvtNinstLnnll 112
                   Ln+i +  +++ + ++++ +a+ +  n+l++d+ +l++e+ t  +++++++++a + l+      d++r++   +++ +t++++++  + ++ +nl 
    EEA21565.1  23 LNSIFSHPSTL-SSVSQTSEALRKYENELDTDIARLVEEQVTSNAESVQRIQAAKADLSelfkkiDDVRERASRTEQSITDMTADIKQLDNAKKNLT 118
                   67775556666.999***************************999999999999999999999999******************************9 PP

  Baculo_PEP_C 113 qalnnldlga 122
                    ++ +l+  +
    EEA21565.1 119 VSMTALKRLQ 128
                   9999986544 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 5.4
  Baculo_PEP_C  67 t 67 
                   +
    EEA21565.1 170 D 170
                   1 PP

>> Exonuc_VII_L  Exonuclease VII, large subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   5.1   0.00072      0.48     143     267 ..      37     155 ..      23     277 .. 0.67

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00072
  Exonuc_VII_L 143 aeleeqleelerrlekaikrlleekkqrleklasrlkspeellerkrqrldeleerleralkkqlkkkrerleelkerlkekleekkerlkklkerl 239
                   ++  e l+++e++l++ i+rl+ee+ +   +  +r++ +++ l++  +++d+++er +r ++++++  ++++++l ++ k    + + ++++l +rl
    EEA21565.1  37 SQTSEALRKYENELDTDIARLVEEQVTSNAESVQRIQAAKADLSELFKKIDDVRERASR-TEQSITDMTADIKQLDNAKK----NLTVSMTAL-KRL 127
                   44566677777777777777776555555555555555555666666666666666666.44444444444444441111....111111222.233 PP

  Exonuc_VII_L 240 elleekkerleeleeklealsplkvLkr 267
                   ++l+++ e+l++l+++ +  +  ++L+ 
    EEA21565.1 128 QMLTTAYEQLRALAKTRQYRDCAQLLQA 155
                   3344444444444444444443333333 PP

>> DUF5082  Domain of unknown function (DUF5082)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.2     0.079        52      73     117 ..      28      75 ..      16      81 .. 0.78
   2 ?    8.0   0.9    0.0051       3.4       3      45 ..      84     126 ..      82     139 .. 0.88

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.079
     DUF5082  73 s..nlessyqtyvdkldelidaieeEIerL.enqiseaqgvldtlqsq 117
                 s  ++ ss+++  + l++ + +++++I rL e+q+++   +++++q +
  EEA21565.1  28 ShpSTLSSVSQTSEALRKYENELDTDIARLvEEQVTSNAESVQRIQAA 75 
                 35678999999999999**********999667777777777777765 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0051
     DUF5082   3 tkisklqaqiaelrseiaaleekIerLkeaktklsdekeslkq 45 
                 +ki +++++++ +++ i ++  +I+ L  ak+ l+    +lk 
  EEA21565.1  84 KKIDDVRERASRTEQSITDMTADIKQLDNAKKNLTVSMTALKR 126
                 7999*****************************9988777765 PP

>> DUF1515  Protein of unknown function (DUF1515)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   3.8    0.0011       0.7      25      71 ..      55     115 ..      33     157 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.0011
     DUF1515  25 k...........rsedrsdasra...kmyrkmdelvervtalegsvvklkaditsvkevte 71 
                             +s +r +a++a   ++++k+d++ er + +e s++ + adi ++ +  +
  EEA21565.1  55 ArlveeqvtsnaESVQRIQAAKAdlsELFKKIDDVRERASRTEQSITDMTADIKQLDNAKK 115
                 233333334555555565555551116799***********************98865444 PP

>> BLOC1_2  Biogenesis of lysosome-related organelles complex-1 subunit 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   3.8    0.0017       1.1      40      91 ..      59     117 ..      31     122 .. 0.64
   2 ?   -1.6   0.0       5.1   3.4e+03      36      47 ..     149     160 ..     116     187 .. 0.47

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0017
     BLOC1_2  40 kdvaaslekkleklnekyeelqpylqqidqi.......ekqvteLeeavseLDeyskeL 91 
                 ++++ s +++++++++ ++ l++++++id++       e+++t++++ +++LD+  k+L
  EEA21565.1  59 EEQVTSNAESVQRIQAAKADLSELFKKIDDVrerasrtEQSITDMTADIKQLDNAKKNL 117
                 44555555556666666666666666666552222222778888888888888887777 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 5.1
     BLOC1_2  36 ykklkdvaasle 47 
                 +++l +++ +l 
  EEA21565.1 149 CAQLLQAVIQLM 160
                 222222222222 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   8.8    0.0018       1.2      18     113 ..      33     129 ..      30     148 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0018
      APG6_N  18 leqaekerdaYeeflkklkkekkeeek.qdeeleeleeeleklekeeeelleeLkelekereeleaelaaleeelealeeeeerfwreynelqlell 113
                 l+++ +  +a+++++++l+++     + q ++ +e+ +++++ +++ +el+++++++ +  ++ e+ + + ++  ++l++ +++   +  +l++ ++
  EEA21565.1  33 LSSVSQTSEALRKYENELDTDIARLVEeQVTSNAESVQRIQAAKADLSELFKKIDDVRERASRTEQSITDMTADIKQLDNAKKNLTVSMTALKRLQM 129
                 556666777788888888876544332466777788888********************************************99999988665544 PP

>> Atg14  Vacuolar sorting 38 and autophagy-related subunit 14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   8.6   0.00025      0.17      31     174 ..      40     199 ..      24     216 .. 0.67
   2 ?   -2.4   0.1       2.9   1.9e+03     128     173 ..     375     436 ..     373     442 .. 0.64

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00025
       Atg14  31 laklksekeslkkkiekalegke.eaeqledkiknkkakleelksliadlrerlqelkdklsqlk...keieekkkklaklsdklkkRrsdleslqnel 125
                    l++  ++l + i +++e++  ++ ++ ++i+  ka+l+el ++i d rer ++ +++++  +   k+++++kk+l     +lk R + l  ++++l
  EEA21565.1  40 SEALRKYENELDTDIARLVEEQVtSNAESVQRIQAAKADLSELFKKIDDVRERASRTEQSITDMTadiKQLDNAKKNLTVSMTALK-RLQMLTTAYEQL 137
                 44555556666666666555544366677778888888888888888888877555555444444000555567777777777775.667777777776 PP

       Atg14 126 ee....rrkkqiaklqdaik.........rieqklsslssktlesrsslcselaklyglrrt 174
                 ++    r+ +  a+l++a++         r+ +++++ls+  ++ +++l++++++ ++++ +
  EEA21565.1 138 RAlaktRQYRDCAQLLQAVIqlmahfksyRSIDQIAALSRNVADVQRELLEQVCEDFEITFS 199
                 54211156666777776666899999999888889********************9999873 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 2.9
       Atg14 128 rrkkqiaklqdaik..rieqklsslssktles..............rsslcselaklyglrr 173
                 ++ kq+a+l+ +++  + ++  ++++ ++  s              +  ++s++++l++l++
  EEA21565.1 375 AQDKQLASLLPKYRqqPLKREDEDFHAQLVISsstelftfyrhslaQCAKLSTGSSLAELSK 436
                 56677777777776554455555555555444455555555566668899999999999988 PP

>> BRE1  BRE1 E3 ubiquitin ligase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.2       2.2   1.4e+03       5      42 ..      33      70 ..      31      77 .. 0.68
   2 ?    9.6   5.9    0.0014       0.9      10      67 ..      70     127 ..      66     142 .. 0.95
   3 ?   -0.2   0.1       1.6   1.1e+03       4      23 ..     126     145 ..     124     178 .. 0.76

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 2.2
        BRE1  5 Lvklekafeelseqlskkvkeltileekklrleaekak 42
                L ++++  e+l++  +++ +++++l e++   +ae  +
  EEA21565.1 33 LSSVSQTSEALRKYENELDTDIARLVEEQVTSNAESVQ 70
                66777777777777777777777777777766666555 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.0014
        BRE1  10 kafeelseqlskkvkeltileekklrleaekakadqkyfaamrskdalenelkkLnkl 67 
                 + ++++++ ls++ k++ +  e+ +r+e+ ++     +++++++k++l+  + +L++l
  EEA21565.1  70 QRIQAAKADLSELFKKIDDVRERASRTEQSITDMTADIKQLDNAKKNLTVSMTALKRL 127
                 6789999************************************************987 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 1.6
        BRE1   4 ELvklekafeelseqlskkv 23 
                  L+ l++a+e+l++++++ +
  EEA21565.1 126 RLQMLTTAYEQLRALAKTRQ 145
                 58999********9998753 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   6.9     0.027        18      25     123 ..      42     126 ..      35     162 .. 0.53

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.027
                 CCCCCCCCCCHHHCCC.CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  25 lllkyekdvkkdlekl.eneleeisnstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlketidaqesnirvLqnvlesneqkiqkLe 122
                 +l kye+++++d+++l e++++++++s + ++    ++++  ++                   +e+ +r +++i++    i++L n  +++ ++++ L+
  EEA21565.1  42 ALRKYENELDTDIARLvEEQVTSNAESVQRIQAAKADLSELFKKIDDV---------------RERASRTEQSITDMTADIKQLDNAKKNLTVSMTALK 125
                 455555555555555433444444444444444444444444433333...............334444444444444444444444444444444443 PP

                 H CS
   Fib_alpha 123 q 123
                  
  EEA21565.1 126 R 126
                 3 PP

>> Syntaxin_2  Syntaxin-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   4.9    0.0067       4.4      11      67 ..      61     127 ..      50     168 .. 0.77
   2 ?   -1.2   0.0       4.2   2.8e+03       5      23 ..     825     844 ..     822     847 .. 0.73

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0067
  Syntaxin_2  11 nvstleklvkqLgtkk.dteelreklhelieeinelikktnellkklsqldnsssds.........q 67 
                 +v++  + v+ ++ +k d  el +k+++++e+++++ + +++   +++qldn +++           
  EEA21565.1  61 QVTSNAESVQRIQAAKaDLSELFKKIDDVRERASRTEQSITDMTADIKQLDNAKKNLtvsmtalkrL 127
                 677777788888888779*******************999999999999999986555444333330 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 4.2
  Syntaxin_2   5 lqkinsnvstleklvkq.Lg 23 
                  +++n+n+++++k+++  Lg
  EEA21565.1 825 TTQLNENLKNIGKFFRRdLG 844
                 57889999999998876555 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   3.2     0.003         2      51     121 ..      37     111 ..      30     136 .. 0.56

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.003
     DUF1664  51 eqvseslaatkrhLssridrvdkkl.deqke...iskeikeevtevredlseigedvesvkeaveglesklerie 121
                  q se+l++  ++L  +i+r+ +++  +++e    +++ k++++e+ +++++++e  +  ++ ++++ + +++++
  EEA21565.1  37 SQTSEALRKYENELDTDIARLVEEQvTSNAEsvqRIQAAKADLSELFKKIDDVRERASRTEQSITDMTADIKQLD 111
                 556666666666666666665433212222200023333445555555555555555555555555555555554 PP

>> HIP1_clath_bdg  Clathrin-binding domain of Huntingtin-interacting protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   7.0    0.0041       2.7      15      99 .]      33     117 ..      31     117 .. 0.95

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0041
  HIP1_clath_bdg  15 lsvarqaqeeverekkeleeelerlkeeaerkleeqkeelekLkreleakraelarlkssLesseqsgeqlssqlaaLqaEkesL 99 
                     ls+  q+ e + +  +el++++ rl ee+    +e  + +++ k++l +  ++++ +++  +++eqs +++++ +++L++ k++L
      EEA21565.1  33 LSSVSQTSEALRKYENELDTDIARLVEEQVTSNAESVQRIQAAKADLSELFKKIDDVRERASRTEQSITDMTADIKQLDNAKKNL 117
                     678889999*********************************************************************9999876 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.1       5.1   3.4e+03      11      44 ..      34      67 ..      30      79 .. 0.65
   2 ?    8.1   1.9    0.0064       4.2       3      61 ..      79     137 ..      77     160 .. 0.78

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 5.1
                HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        YabA 11 eeleeqleelleeleelkeelaelleenaeLele 44
                ++++++ e+l +  +el +++a+l+ee  + ++e
  EEA21565.1 34 SSVSQTSEALRKYENELDTDIARLVEEQVTSNAE 67
                5556666666666677777777777776655554 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0064
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHXXXXXXXXX CS
        YabA   3 kkelfdkleeleeqleelleeleelkeelaelleenaeLeleneklrerleeeekkeke 61 
                  +elf+k++++ e+ +++ ++++++ +++++l +  ++L++  + l++++  +++ e+ 
  EEA21565.1  79 LSELFKKIDDVRERASRTEQSITDMTADIKQLDNAKKNLTVSMTALKRLQMLTTAYEQL 137
                 579***************************************99999987333333333 PP

>> TPR_MLP1_2  TPR/MLP1/MLP2-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   7.2    0.0012      0.81      38      95 ..      55     108 ..      29     128 .. 0.72
   2 ?   -0.7   0.3         2   1.4e+03      54      74 ..     105     125 ..      97     147 .. 0.40

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0012
  TPR_MLP1_2  38 akeaqqkYerelvkhaedvkelqalreelnelkaeiaelkaeaesakaeleeseeswe 95 
                 a+      e++++ +ae v+ +qa++++l+el ++i +++++a ++++++   ++ ++
  EEA21565.1  55 ARLV----EEQVTSNAESVQRIQAAKADLSELFKKIDDVRERASRTEQSITDMTADIK 108
                 4444....5599*******************************999998877665544 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 2
  TPR_MLP1_2  54 edvkelqalreel...nelkaeia 74 
                 +d+k+l ++++ l       + ++
  EEA21565.1 105 ADIKQLDNAKKNLtvsM---TALK 125
                 45555555555542221...2211 PP

>> NPV_P10  Nucleopolyhedrovirus P10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   3.0     0.024        16      15      61 ..      57     103 ..      50     140 .. 0.87
   2 ?   -0.1   0.0       2.1   1.4e+03      18      34 ..     170     186 ..     164     195 .. 0.75

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.024
     NPV_P10  15 avddkVdalqqqvddvqenlpdvtelnekLdaqsaqLaeletkvenI 61 
                  v+++V++  ++v+++q+   d++el +k+d+  +     e+++++ 
  EEA21565.1  57 LVEEQVTSNAESVQRIQAAKADLSELFKKIDDVRERASRTEQSITDM 103
                 479999999**********************9998887777776665 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 2.1
     NPV_P10  18 dkVdalqqqvddvqenl 34 
                 d++ al+ +v+dvq +l
  EEA21565.1 170 DQIAALSRNVADVQREL 186
                 57778888888887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (859 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1630  (0.0909142); expected 358.6 (0.02)
Passed bias filter:                      850  (0.0474092); expected 358.6 (0.02)
Passed Vit filter:                       123  (0.00686039); expected 17.9 (0.001)
Passed Fwd filter:                        28  (0.00156172); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              27  [number of targets reported over threshold]
# CPU time: 0.97u 0.37s 00:00:01.34 Elapsed: 00:00:00.59
# Mc/sec: 4405.60
//
Query:       EEA21566.1  [L=619]
Description: acylamino-acid-releasing enzyme, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.8e-31  109.3   0.9    3.3e-31  108.4   0.9    1.4  1  Peptidase_S9  Prolyl oligopeptidase family


Domain annotation for each model (and alignments):
>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  108.4   0.9   1.8e-35   3.3e-31      27     210 ..     434     616 ..     427     618 .. 0.94

  Alignments for each domain:
  == domain 1  score: 108.4 bits;  conditional E-value: 1.8e-35
                   TTHCHHHHTTSGGGGHHHHHHHHHHHHHHHHTT.S--GGGEEEEEETHHHHHHHHHHH.H-GGG-SEEEEESE---CCCHHCSTTSTHH.HCCCC-- CS
  Peptidase_S9  27 gyGeafhdagkrklgqnefdDfiaaaealakeg.yvdserlaitGgSyGGyltgaaln.qrpdlFkaavaevpvvdvlrydsdtdllte.eymewgn 120
                    yG+ f+da+++ +g  +++D+ ++ e++ ++  y++ er ++ G+ yGGy+++++++ + ++lFka++  ++++ + ++   +  ++  +++++g 
    EEA21566.1 434 SYGQGFTDAIRGSWGGLQYNDLQKVFEYVQNNVnYANIERAVAIGHGYGGYMVNWIQGhDFGRLFKALITDNGIFSMKTQLAGN--MQSlRHDFNGL 528
                   79****************************9999************************99**********************98..88889999999 PP

                   TTTCHHHHHHHHHH-CGGG-----EEEEEEETT-SSS-THHHHHHHHHHH--S-SEEEEEETTS-SSTTSSHHHHHHHHHHHHHHHHHCT CS
  Peptidase_S9 121 peeneegykelspyspldnvkaypplLlihGlaDdrvppaealklvaaLqkkgknvlllifpdegHgvgkprakveelarllaFlkealg 210
                   p+en  + +++ p++++ +  +++p L+ih ++  + p+a++l  +++Lq +g++++ll+fpde H+ ++p++   ++++l +++++ ++
    EEA21566.1 529 PRENSSEWQKWDPAQYAGH--WQTPHLVIHNELNLQQPLAQGLASFHTLQLRGVETMLLTFPDESHSHKNPENLLLWYHTLIDWMDKFVK 616
                   9888888888888888888..****************************************************************99776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (619 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       399  (0.0222544); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.30s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 4007.56
//
Query:       EEA21567.1  [L=183]
Description: hypothetical protein PMAA_053710 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.2e-23   80.7   1.5    2.1e-22   79.4   0.3    1.9  2  DUF4149   Domain of unknown function (DUF4149)


Domain annotation for each model (and alignments):
>> DUF4149  Domain of unknown function (DUF4149)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.4   0.3   1.2e-26   2.1e-22       1     101 [.      14     114 ..      14     115 .. 0.97
   2 ?    0.1   0.0     0.057     1e+03      54      83 ..     144     171 ..     142     179 .. 0.59

  Alignments for each domain:
  == domain 1  score: 79.4 bits;  conditional E-value: 1.2e-26
     DUF4149   1 lslglllGsqlwvtfvvapvlfrsLprhqfgelqsklFplyfglglalsvlllltevavgseklaseellqlllllvvllltllnafylepritslkeq 99 
                 l++g+ lGsql+++fv++ +++rsL+++ f +l ++lFp+yf+++l+l++l+ +t + + + +l +++ +  lll+++ +++ ln+++++pr+++++ +
  EEA21567.1  14 LAYGTFLGSQLYQSFVNTKICYRSLSPQSFNNLNKRLFPVYFRCQLGLAILTFVTRPSKAWLQLPAANDVGNLLLALATIMAGLNWYVYGPRTSEAMVE 112
                 689******************************************************9999999999******************************98 PP

     DUF4149 100 re 101
                 ++
  EEA21567.1 113 KA 114
                 75 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.057
     DUF4149  54 ltevavgseklaseellqlllllvvllltl 83 
                 +t v++      +++++  + l++v++++ 
  EEA21567.1 144 VTKVKKI--FSRNHAMSIHINLIAVIATVG 171
                 5566555..555666666666666666554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (183 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       807  (0.0450109); expected 358.6 (0.02)
Passed bias filter:                      615  (0.034302); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.27s 00:00:00.68 Elapsed: 00:00:00.39
# Mc/sec: 1395.11
//
Query:       EEA21568.1  [L=313]
Description: 60S ribosomal protein P0 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-22   79.9   0.1    3.1e-22   78.6   0.0    1.7  2  Ribosomal_L10  Ribosomal protein L10
      1e-21   76.7   0.1    2.1e-21   75.7   0.1    1.6  1  RL10P_insert   Insertion domain in 60S ribosomal protein L10P
    2.8e-18   66.3   6.4    2.8e-18   66.3   6.4    2.0  2  Ribosomal_60s  60s Acidic ribosomal protein


Domain annotation for each model (and alignments):
>> Ribosomal_L10  Ribosomal protein L10
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.6   0.0   5.1e-26   3.1e-22       3      95 ..       5     100 ..       3     105 .. 0.92
   2 ?   -2.5   0.0      0.98   5.9e+03      57      82 ..     246     274 ..     238     283 .. 0.60

  Alignments for each domain:
  == domain 1  score: 78.6 bits;  conditional E-value: 5.1e-26
                    CCCHCCCCCCCCCCCTTSSEEEEEE-TTS-HHHHHHCCCHHHHHGCEEEEESCCCCCCCCHCCTSS.S....SCGCCSSSEEEEEESS-TCHHHHC CS
  Ribosomal_L10   3 kekKeelvkelkellkkyksvvvvdyegltvaqlqelRkklrengaelkvvKntlmrrAleetgeeek....lkellkgpvalvftnedpvalakv 94 
                     + K++++++lk ll++yk++++v++++++++q++e+R +lr++ + + ++Knt++rrAl++  +e+     l +++kg+v+++ftn d + +  +
     EEA21568.1   5 SASKAAYFDKLKGLLDEYKTIFIVSVDNVSSQQMHEIRLSLRGE-GVVLMGKNTMVRRALKGFIAENPeyerLLPFVKGNVGFIFTNADLKGVRTK 99 
                    689****************************************9.*****************999853578899***************9998766 PP

                    C CS
  Ribosomal_L10  95 l 95 
                    +
     EEA21568.1 100 I 100
                    6 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.98
                    CCCCCCHCCTSS.S...SCGCCSSSEEEE CS
  Ribosomal_L10  57 lmrrAleetgeeek...lkellkgpvalv 82 
                    ++  A+e+   + +   lk+ +++p a++
     EEA21568.1 246 VLAVAIETEFSWPEieeLKDRIANPEAYA 274
                    55555555444421344777777776665 PP

>> RL10P_insert  Insertion domain in 60S ribosomal protein L10P
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.7   0.1   3.6e-25   2.1e-21       1      71 []     109     178 ..     109     178 .. 0.99

  Alignments for each domain:
  == domain 1  score: 75.7 bits;  conditional E-value: 3.6e-25
  RL10P_insert   1 AraGtiAtedviipagplelaPgsiepeLrklglptklkkGkivleedylvckkGetltseqaqlLklLgi 71 
                   AraG++A+ dv++pag+++++Pg++ +++++lg+ptk+ +G+i++++d +++++G ++++++a lL++L+i
    EEA21568.1 109 ARAGAVAPLDVFVPAGNTGMEPGKT-SFFQALGVPTKIARGTIEITTDLKLVEAGAKVGASEAVLLNMLNI 178
                   9************************.*******************************************98 PP

>> Ribosomal_60s  60s Acidic ribosomal protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.1      0.65   3.9e+03      47      58 ..     101     113 ..      83     116 .. 0.53
   2 !   66.3   6.4   4.7e-22   2.8e-18       1      88 []     229     312 ..     229     312 .. 0.82

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.65
                    X.XXXXXXXXXXX CS
  Ribosomal_60s  47 a.aaaaaaaaaaa 58 
                    +  ++aa+a a+a
     EEA21568.1 101 LsNRVAAPARAGA 113
                    2434444444443 PP

  == domain 2  score: 66.3 bits;  conditional E-value: 4.7e-22
                    XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XX--SS--STTT CS
  Ribosomal_60s   1 eptaenikkvlkaagveveaarvkllvkalegkdieellangaaklaaaaaaaaaaaaaaaaaaaaeekkkeeeeeEeedddmGfgLF 88 
                    +pt +++ ++l +++++v+a+++++++++ e +++++ +an++a+  a+aa  aaaa  ++aa+aa+e+k+e ee E+ d+ +G gLF
     EEA21568.1 229 YPTLASVMHSLVNSYKKVLAVAIETEFSWPEIEELKDRIANPEAY--ASAAPVAAAASSSEAAPAAAEEKEESEE-ESGDEGFG-GLF 312
                    69*******************************************..7766666666666666666666666665.55566666.999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (313 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       704  (0.039266); expected 358.6 (0.02)
Passed bias filter:                      570  (0.0317921); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.48
# Mc/sec: 1971.07
//
Query:       EEA21569.1  [L=483]
Description: tRNA methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.1e-05   24.3   3.1       0.15   13.0   0.1    4.4  4  WD40         WD domain, G-beta repeat
  ------ inclusion threshold ------
      0.052   12.8   0.0       0.15   11.3   0.0    1.7  2  Lactonase    Lactonase, 7-bladed beta-propeller
      0.055   13.8   0.0         30    5.0   0.0    3.2  4  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.5   0.0     0.006        36      18      37 ..      93     113 ..      81     114 .. 0.81
   2 ?    2.0   0.1     0.076   4.5e+02      14      29 ..     134     149 ..     124     154 .. 0.83
   3 ?   -0.1   0.0      0.34   2.1e+03      18      36 ..     239     257 ..     215     257 .. 0.61
   4 !   13.0   0.1   2.5e-05      0.15       9      38 .]     273     304 ..     264     304 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.006
                 EETTSSEEEEE.ETTSEEEEE CS
        WD40  18 fspdgawlasG.sdDgtvriW 37 
                  sp+g+ +++   +D++vr++
  EEA21569.1  93 ISPSGRHVVAVtAEDKHVRVF 113
                 699****8754357*****97 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.076
                 EEEEEETTSSEEEEEE CS
        WD40  14 tslafspdgawlasGs 29 
                 +++afs+d + l++++
  EEA21569.1 134 CAVAFSSDEDTLICAD 149
                 6899********9654 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.34
                 EETTSSEEEEEETTSEEEE CS
        WD40  18 fspdgawlasGsdDgtvri 36 
                  s ++++++++++D  +r+
  EEA21569.1 239 ASGSHSFILTADRDEQIRV 257
                 4666677889988988886 PP

  == domain 4  score: 13.0 bits;  conditional E-value: 2.5e-05
                 SS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS
        WD40   9 GH.ssvtslafspdgaw.lasGsdDgtvriWd 38 
                 GH s+++ l+ ++  +  l++G+ D ++ +Wd
  EEA21569.1 273 GHeSFISTLCIPSTLPHlLVTGGGDDSIFVWD 304
                 9*889*999966666662679977*******9 PP

>> Lactonase  Lactonase, 7-bladed beta-propeller
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   2.5e-05      0.15     249     332 ..      91     172 ..      57     182 .. 0.70
   2 ?   -2.4   0.0      0.37   2.2e+03     156     176 ..     289     309 ..     286     319 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 2.5e-05
                 EEE-TTSSEEEEEETSSTEEEEEEE-TTT--EEEEEEEE-SSS.--EEEE-TTSSEEEEEETTTTEEEEEEEETTTTEEEEESE CS
   Lactonase 249 IrlspdgkflyvSnRgadsiavfavdeadgtltlveevstegkfPRdfaldpsgklllvanqksdnvtvferdaetGkLtelgk 332
                 +++sp+g+++++    +  + vf++ + +g lt+    ++  + P   a++++++ l++a++  d  ++     e+G+ + +++
  EEA21569.1  91 LVISPSGRHVVAVTAEDKHVRVFEI-STGGVLTESSDRPVPRR-PCAVAFSSDEDTLICADKGGDVFSMPLLPGESGEFELVSR 172
                 5677777777777777777777777.77777777777777555.7777777777777777777776666666666666666555 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.37
                 EEEEEETTTTEEEEEEE.-TT CS
   Lactonase 156 fllvpDLGtDrvrvykldkat 176
                 +llv+  G D+++v+++ +++
  EEA21569.1 289 HLLVTGGGDDSIFVWDWRNGK 309
                 688888999******997655 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.0    0.0052        31      47      77 ..      94     125 ..      78     158 .. 0.83
   2 ?   -3.3   0.0         2   1.2e+04      46      71 ..     177     202 ..     170     214 .. 0.74
   3 ?    5.0   0.0    0.0051        30      36      78 ..     273     316 ..     243     332 .. 0.72
   4 ?   -3.1   0.0       1.6   9.8e+03      15      35 ..     422     442 ..     419     451 .. 0.71

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.0052
  ANAPC4_WD40  47 kpdg.klLavaysdgevrlldaesgkvvhsls 77 
                  +p+g ++ av  +d +vr++++++g v+ ++s
   EEA21569.1  94 SPSGrHVVAVTAEDKHVRVFEISTGGVLTESS 125
                  566636889999999*********99988765 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 2
  ANAPC4_WD40  46 WkpdgklLavaysdgevrlldaesgk 71 
                  +kp  + L+v ++ + ++l++  ++k
   EEA21569.1 177 FKPAANPLVVHTKRNLISLHQQLNQK 202
                  66777778888888888887776666 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.0051
  ANAPC4_WD40  36 kedsevrsLaW.kpdgklLavaysdgevrlldaesgkvvhslsv 78 
                  +++s ++ L+  +   +lL+ +  d ++ + d  +gk++h++s+
   EEA21569.1 273 GHESFISTLCIpSTLPHLLVTGGGDDSIFVWDWRNGKLLHKVSI 316
                  555556666652344699***********************986 PP

  == domain 4  score: -3.1 bits;  conditional E-value: 1.6
  ANAPC4_WD40  15 edgellvfRlngqrvwtleed 35 
                  +dg+l + R   q +  ++++
   EEA21569.1 422 KDGKLSLDRAASQAINYINKQ 442
                  688888888888888777444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (483 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       403  (0.0224776); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 3148.18
//
Query:       EEA21570.1  [L=363]
Description: uroporphyrinogen decarboxylase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.8e-128  427.9   0.0   3.1e-128  427.8   0.0    1.0  1  URO-D     Uroporphyrinogen decarboxylase (URO-D)


Domain annotation for each model (and alignments):
>> URO-D  Uroporphyrinogen decarboxylase (URO-D)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  427.8   0.0  1.7e-132  3.1e-128       2     346 .]       9     361 ..       8     361 .. 0.96

  Alignments for each domain:
  == domain 1  score: 427.8 bits;  conditional E-value: 1.7e-132
                 ---HHHHHHTT---SS--B--TT-SSTTSHHHHHHHTSSSHHHHHH-HHHHHHHHHHHHHHH-..-S-EE-S--TTGGGGGGT-EEEEETTTEEEEE-- CS
       URO-D   2 knerllralrgekvdrvPvwlmRqaGrylpeyraeragvsflelcknpelaaevtlqpvrrfg..lDaailfsdilveaealGlevefeegegPvvekp 98 
                 kn++llra+rge+v+r+P+w+mRqaGrylpey++ + + +f+++c++pe a+ +tlqp++r+   +Daai+fsdilv+++a+G+ ve+ +++gP++++p
  EEA21570.1   9 KNDLLLRAARGETVERPPMWVMRQAGRYLPEYHEAKGNRDFFDCCRSPEIASTLTLQPIERYAglIDAAIIFSDILVIPQAMGMVVEMIDKKGPSFPQP 107
                 89************************************************************999********************************** PP

                 S-......GGGS----GGG.G..HHHHHHHHHHHHH.--SS-EEEEEE-HHHHHHHHHCTT.-SS-HHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHH CS
       URO-D  99 vrtaed..veklevpddveegrlpyvleaikllkkelggevpligfvgaPftlasylveGg.skgfekllkllykdpeevhklldkltdvvieylkaqi 194
                 +++++d  +ek+ ++d+  +++l+yv++ai+l++ +l+g+vpligf+gaP+tl++y+veGg +k f + +k++yk+p+e +++l+k++++++eyl+ q+
  EEA21570.1 108 LVSPDDgqYEKILKKDVDVKKELDYVYKAITLTRFKLKGRVPLIGFCGAPWTLLCYMVEGGgTKMFIQSKKWIYKYPNESKAMLQKIAELCVEYLALQV 206
                 **99995556775555543489***************************************************************************** PP

                 HTT-SEEEEEETTGGGS-HHHHHHHTHHHHHHHHHHHHH.H-.....-S-EEEEESSHH.HHHHHHTTS--SEEE--TTS-HHHHHHSS....EEE--B CS
       URO-D 195 eagAdaiqifDswagllspedfeefvlpylkrivdevkaegp.....kvpvilfikgagaeiledlaelgadvlsldwtvdlkeaarevgdkvalqGnl 288
                  agA+++q+fDswag lsp+ f+ef+lpyl+ i ++++++ +     +vp+++f+kga+ + ledl+e+g++v++ldw +d++ea r    +v+lqGn 
  EEA21570.1 207 TAGAQLVQVFDSWAGELSPATFKEFSLPYLRYISEHLPKRLQelgleRVPMTVFAKGAW-YALEDLCESGYNVVGLDWLHDPAEAYRIARGRVTLQGNA 304
                 ***********************************************************.9*********************88888888********* PP

                 -G.GGGGS-HHHHHHHHHHHHT.T---SSSEEB-BSS---TTS-HHHHHHHHHHHHT- CS
       URO-D 289 dPialLlgspeeiekevkeilekgaggkkgyilnlGhgippetppenvkalveavkey 346
                 dP  +L+g++ +i k v++++++  ggkkg+i+nlGhgi+p ++pe +k ++e ++++
  EEA21570.1 305 DP-GILYGDRSAITKTVEDMVKGFGGGKKGWIANLGHGITPLVNPEDLKFFFEEIHRH 361
                 **.9******************88899****************************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (363 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       329  (0.0183502); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2746.57
//
Query:       EEA21571.1  [L=148]
Description: cytosine deaminase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.7e-22   78.1   0.0    5.1e-22   77.7   0.0    1.2  1  dCMP_cyt_deam_1  Cytidine and deoxycytidylate deaminase zinc-
    9.2e-19   67.6   0.0    1.1e-18   67.3   0.0    1.1  1  MafB19-deam      MafB19-like deaminase
     0.0003   20.8   0.4      0.059   13.5   0.8    2.2  2  Bd3614-deam      Bd3614-like deaminase
      0.004   17.3   0.0      0.028   14.5   0.0    2.0  2  SNAD4            Secreted Novel AID/APOBEC-like Deaminase 4
  ------ inclusion threshold ------
      0.014   15.5   0.1       0.22   11.5   0.1    2.0  1  APOBEC2          APOBEC2
      0.019   15.1   0.2       0.21   11.7   0.2    2.1  1  NAD1             Novel AID APOBEC clade 1
      0.029   14.3   0.1       0.27   11.1   0.1    2.0  1  APOBEC_N         APOBEC-like N-terminal domain
       0.05   13.7   0.0       0.15   12.1   0.0    1.8  1  NAD2             Novel AID APOBEC clade 2
       0.14   12.5   0.0       0.21   11.9   0.0    1.3  1  DUF3725          Protein of unknown function (DUF3725)


Domain annotation for each model (and alignments):
>> dCMP_cyt_deam_1  Cytidine and deoxycytidylate deaminase zinc-binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.7   0.0   2.6e-25   5.1e-22      10     100 ..       9     100 ..       2     101 .. 0.95

  Alignments for each domain:
  == domain 1  score: 77.7 bits;  conditional E-value: 2.6e-25
                      HHHHHHHHHHTTTSCSEEEEEEE.TTEEEEEEESBHHCCTGTTB-HHHHHHHHHHHHTSSCETTEEEEEEE--BHHHHHHHHHHT-SEEEEE CS
  dCMP_cyt_deam_1  10 lalkaakeaqkcsnfkVGavivk.ngeiistgyngepaggsktiHAEvnAilkaaknggsklegatlyvtlePCsmCakaiiqsgikkvvvg 100
                       a+++a++ q++  +++Ga++v  +g+i+++g+n+++++gs t+H E++A+ + ++ + s  egat+y+tl+PC mC+ a i  ++k+vvvg
       EEA21571.1   9 AAVEEARQGQAEGGVPIGACLVSkDGKILGRGHNMRFQKGSATLHGEISALENSGRLPASAYEGATMYTTLSPCDMCTGACILYKVKRVVVG 100
                      5889999999***********************************************97799****************************98 PP

>> MafB19-deam  MafB19-like deaminase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.3   0.0   5.5e-22   1.1e-18       9     136 ..       9     137 ..       1     138 [. 0.83

  Alignments for each domain:
  == domain 1  score: 67.3 bits;  conditional E-value: 5.5e-22
  MafB19-deam   9 kalaevekatkikedkiga.vivkdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkklvygagnpk 105
                   a++e++++   ++++iga +++kd+k+++rg+n + ++ +at H+Ei al+     l ++  ++at+y+tl pCdmC ga +  ++k++v g + + 
   EEA21571.1   9 AAVEEARQGQAEGGVPIGAcLVSKDGKILGRGHNMRFQKGSATLHGEISALENS-GRLPASAYEGATMYTTLSPCDMCTGACILYKVKRVVVGEN-KT 104
                  678899999999******96777*****************************99.6777777******************************998.44 PP

  MafB19-deam 106 slnkLkvkekngrvelv...eddckeilkgffkk 136
                  +l   + + ++  +e+v   +++c +++ +f+++
   EEA21571.1 105 FLGG-EQYLQSRGIEVVvlqNEECIKLMTDFIRE 137
                  4433.334444444444467999999**999986 PP

>> Bd3614-deam  Bd3614-like deaminase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.3   0.0    0.0099        20      10      42 ..      25      59 ..      22      66 .. 0.83
   2 !   13.5   0.8   2.9e-05     0.059      76      98 ..      71      93 ..      60     118 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0099
  Bd3614-deam 10 vvAalvsdqGelldaavntn..aenkvLHAEvnLl 42
                 + A lvs++G++l  + n     + ++LH E+  l
   EEA21571.1 25 IGACLVSKDGKILGRGHNMRfqKGSATLHGEISAL 59
                 5699**************85226789***998765 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 2.9e-05
  Bd3614-deam 76 egarllvtlqcCkmCAalvvaaa 98
                 ega+++ tl +C mC +  + + 
   EEA21571.1 71 EGATMYTTLSPCDMCTGACILYK 93
                 89*************98766554 PP

>> SNAD4  Secreted Novel AID/APOBEC-like Deaminase 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.0   1.4e-05     0.028      18      59 ..      47      88 ..      30      99 .. 0.78
   2 ?    0.5   0.0      0.32   6.3e+02      55      69 ..     126     140 ..     110     142 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 1.4e-05
       SNAD4 18 knkke.haEllflekikseldpsqeyrvtwylswsPCaeCaek 59
                k +++ h E+  le+   +l +s     t+y++ sPC  C+ +
  EEA21571.1 47 KGSATlHGEISALENS-GRLPASAYEGATMYTTLSPCDMCTGA 88
                223337*********9.8899999999*************865 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.32
       SNAD4  55 eCaekiaeflaehpn 69 
                 eC++ +++f++e+p+
  EEA21571.1 126 ECIKLMTDFIREKPE 140
                 699999999999886 PP

>> APOBEC2  APOBEC2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.1   0.00011      0.22      47      88 ..      49      88 ..      30     145 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00011
     APOBEC2 47 ekkcHaEllflskvkkkkleekkeyk.vtwyvswsPCaeCaee 88
                +++ H E+  l++     l +++ y+  t+y++ sPC  C+  
  EEA21571.1 49 SATLHGEISALENSGR--L-PASAYEgATMYTTLSPCDMCTGA 88
                4566999888888777..4.55566548************875 PP

>> NAD1  Novel AID APOBEC clade 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.2   0.00011      0.21      47      87 ..      50      87 ..      29     145 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00011
        NAD1 47 skcHaEllflnkikslklldpsqkykvtwylswSPCseCas 87
                ++ H E+  l++   l     s+    t+y++ SPC+ C+ 
  EEA21571.1 50 ATLHGEISALENSGRL---PASAYEGATMYTTLSPCDMCTG 87
                3457787776666333...34566678************64 PP

>> APOBEC_N  APOBEC-like N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.1   0.00014      0.27      37      88 ..      41      89 ..      27     141 .. 0.65

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00014
                E.EEEE-..SSTBCHHHHHHHHHHHH.T--.TTEEEEEEEEESS-S-HH....H CS
    APOBEC_N 37 v.LrnqsgaaaskHaEelflediedq.elrepkkkyeitlYvswsPChessdeC 88
                + +r q+g+ a  H E   le+      l+  +     t+Y+++sPC   +  C
  EEA21571.1 41 HnMRFQKGS-ATLHGEISALEN---SgRLP-ASAYEGATMYTTLSPCDMCTGAC 89
                444445544.368888886664...33555.3555569*********9944444 PP

>> NAD2  Novel AID APOBEC clade 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   7.6e-05      0.15      49      97 ..      46      93 ..      29     143 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 7.6e-05
        NAD2 49 qk.esklhaellfLskfvlrqlelaqeykvtwyvsWsPCpeCaaevaefl 97
                qk ++ lh e++ L+     +l+++     t+y++ sPC  C++  + ++
  EEA21571.1 46 QKgSATLHGEISALENS--GRLPASAYEGATMYTTLSPCDMCTGACILYK 93
                2237889*****99998..58999998889************98877665 PP

>> DUF3725  Protein of unknown function (DUF3725)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   0.00011      0.21       5      43 ..      82     120 ..      78     142 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00011
     DUF3725   5 FkvsdGAkilqLvvignaeigreFLEgnrfvRanileiv 43 
                  +++ GA+il+ v        ++FL g++      +e+v
  EEA21571.1  82 CDMCTGACILYKVKRVVVGENKTFLGGEQYLQSRGIEVV 120
                 579************************998877666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (148 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       433  (0.0241508); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.47
# Mc/sec: 954.47
//
Query:       EEA21572.1  [L=410]
Description: protein mitochondrial targeting protein (Mas1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.3e-39  135.7   0.1    1.7e-39  135.3   0.1    1.2  1  DnaJ_C          DnaJ C terminal domain
      5e-26   90.6   1.4    8.4e-26   89.9   1.4    1.4  1  DnaJ            DnaJ domain
    1.1e-15   57.7  18.5      2e-15   56.9  18.5    1.4  1  DnaJ_CXXCXGXG   DnaJ central domain
  ------ inclusion threshold ------
       0.12   11.6   2.7        1.4    8.1   0.3    2.2  2  DUF1356         Protein of unknown function (DUF1356)
       0.28   11.3   6.0        1.1    9.4   1.0    2.2  2  DUF2614         Zinc-ribbon containing domain
        1.2    9.2   9.7       0.64   10.1   2.4    2.3  2  HypA            Hydrogenase/urease nickel incorporation, meta
        1.2    9.2   7.4        1.9    8.6   1.8    2.2  2  zinc-ribbons_6  zinc-ribbons
        1.7    8.7  17.3       0.15   12.0   2.7    2.9  4  Anti-TRAP       Tryptophan RNA-binding attenuator protein inh


Domain annotation for each model (and alignments):
>> DnaJ_C  DnaJ C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  135.3   0.1   7.6e-43   1.7e-39       2     148 .]     120     339 ..     119     339 .. 0.96

  Alignments for each domain:
  == domain 1  score: 135.3 bits;  conditional E-value: 7.6e-43
                 EEEEEE-HHHHHH-.EEE.EEEE..........................................................................TE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxx...................................................................xxxxxx RF
      DnaJ_C   2 eveleisleelykGktkkikikrnvi...................................................................kkekkt 33 
                 ++  ++sle++y+Gk  k+++++ vi                                                                   ++e+k+
  EEA21572.1 120 NHVHKVSLEDIYRGKVSKLALQKSVIcpgcdgrggkegavrqctgcngsgmktmmrqmgpmiqrfqtvcpdcqgegeilrekdrckkcngkktIVERKV 218
                 67789*******************99*****************************************************************99889999 PP

                 EEEEE-TT--TT-EEEETT-SSSS...S---EEEEEEE---SS-EEETTEEEEEEEEEHHHHHHTEEEEEE-S.S-EEEEEE.....--TT-EEEETT- CS
                 xxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxx.....xxxxxxxxxxxx RF
      DnaJ_C  34 levkipaGikdgqkirlegeGdeeg.gepGDlivtikvkphpvFkrkgndlyveveislaeallGgklevptl.dgkvklki.....tqpgevlrikgk 125
                 l+v++++G+k+g+ki ++geGd+ + + pGD++++i++kphp+F+r+++dl++++ei+l +al Gg++ ++ l d+  +++i     + pg +++ikg+
  EEA21572.1 219 LHVHVDKGVKNGHKIEFRGEGDQMPnVLPGDVVFEIEQKPHPRFQRRDDDLFYHAEIDLLTALAGGTIHIEHLdDRWLSVNIapgepITPGAIKVIKGQ 317
                 **********************9999***********************************************54455667777888************ PP

                 S-EET...TEE--EEEEEEEE-- CS
                 xxxxxxxxxxxxxxxxxxxxxxx RF
      DnaJ_C 126 GmpklkkpgkrGdlyvevkvefP 148
                 Gmp+ + ++ +G+ly++++v+fP
  EEA21572.1 318 GMPSFR-HHDFGNLYIQFDVKFP 339
                 *****8.***************9 PP

>> DnaJ  DnaJ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.9   1.4   3.8e-29   8.4e-26       2      63 .]       7      68 ..       6      68 .. 0.99

  Alignments for each domain:
  == domain 1  score: 89.9 bits;  conditional E-value: 3.8e-29
                HHHHHTSSTTG-HHHHHHHHHHHHHHHSTTTSCCHHHHHHHHHHHHHHHHHHTSHHHHHHHH CS
        DnaJ  2 yYeiLgvskdasedeIkkaYrklalkyHPDknpkdpeaeekFkeineAyevLsdpekRkqYD 63
                +Y+iLgv+++a+e+++k aY+k alkyHPDkn+++pea++kFke+++Aye+Lsd++kR++YD
  EEA21572.1  7 LYDILGVPPTATEAQLKTAYKKGALKYHPDKNASNPEAADKFKELSHAYEILSDSQKRQIYD 68
                8************************************************************9 PP

>> DnaJ_CXXCXGXG  DnaJ central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.9  18.5   8.8e-19     2e-15       1      67 []     146     211 ..     146     211 .. 0.93

  Alignments for each domain:
  == domain 1  score: 56.9 bits;  conditional E-value: 8.8e-19
  DnaJ_CXXCXGXG   1 CkkCkGsgakkgkkktCktCkGsG.vvreeqktlgpfvqqsqstCpeCeGtGkvikekdkCkkCkGkg 67 
                    C+ C+G+g k+g++++C+ C+GsG +++++q  +gp++q++q+ Cp+C+G+G++++ekd+CkkC+Gk+
     EEA21572.1 146 CPGCDGRGGKEGAVRQCTGCNGSGmKTMMRQ--MGPMIQRFQTVCPDCQGEGEILREKDRCKKCNGKK 211
                    9***********************4455555..9********************************86 PP

>> DUF1356  Protein of unknown function (DUF1356)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.1     0.015        34      24      42 ..     135     153 ..     114     163 .. 0.82
   2 ?    8.1   0.3   0.00062       1.4      32      49 ..     185     202 ..     164     205 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.015
     DUF1356  24 yveatgrdsvtCptCqGtG 42 
                 + + + ++sv+Cp C G G
  EEA21572.1 135 VSKLALQKSVICPGCDGRG 153
                 56778899*********98 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.00062
     DUF1356  32 svtCptCqGtGeiPreqe 49 
                   +Cp CqG+Gei re++
  EEA21572.1 185 QTVCPDCQGEGEILREKD 202
                 568**********99976 PP

>> DUF2614  Zinc-ribbon containing domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.4     0.018        40      59      91 ..     133     167 ..     123     180 .. 0.81
   2 ?    9.4   1.0   0.00049       1.1      66      95 ..     184     213 ..     170     220 .. 0.87

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.018
     DUF2614  59 Gllstkavq..vvcpeceketkvlGrvdlcmhcde 91 
                 G +s  a+q  v+cp c+ +    G v  c  c+ 
  EEA21572.1 133 GKVSKLALQksVICPGCDGRGGKEGAVRQCTGCNG 167
                 555665554349********999*********985 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.00049
     DUF2614  66 vqvvcpeceketkvlGrvdlcmhcdepltl 95 
                  q vcp+c+ e  +l   d c +c+   t+
  EEA21572.1 184 FQTVCPDCQGEGEILREKDRCKKCNGKKTI 213
                 6789********************987775 PP

>> HypA  Hydrogenase/urease nickel incorporation, metallochaperone, hypA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.7     0.034        75      68      99 ..     141     172 ..     125     183 .. 0.83
   2 ?   10.1   2.4   0.00029      0.64      68     100 ..     183     214 ..     172     223 .. 0.79

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.034
                 --EEEETTTS-EEECHHHHHS-TTTSSS-EEE CS
        HypA  68 pvkvrCreCgkefeleekalrCpkCgsadvei 99 
                 + +v C  C+ ++ +e +  +C  C+++++++
  EEA21572.1 141 QKSVICPGCDGRGGKEGAVRQCTGCNGSGMKT 172
                 45789*****99998766668****9988765 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00029
                 --EEEETTTS-EEECHHHHHS-TTTSSS-EEEE CS
        HypA  68 pvkvrCreCgkefeleekalrCpkCgsadveiv 100
                 + ++ C +C+ e+e+ +++ rC+kC+++++ iv
  EEA21572.1 183 RFQTVCPDCQGEGEILREKDRCKKCNGKKT-IV 214
                 67899*********6655579*****9875.44 PP

>> zinc-ribbons_6  zinc-ribbons
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.4      0.04        90       2      24 ..     145     167 ..     144     177 .. 0.86
   2 ?    8.6   1.8   0.00083       1.9       2      26 ..     187     211 ..     186     217 .. 0.86

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.04
                     --SSS-S--EE-SSEEE-TTT-- CS
  zinc-ribbons_6   2 kCpeCqqelekrgeqyhCeaCqe 24 
                     +Cp C+    k+g+  +C  C+ 
      EEA21572.1 145 ICPGCDGRGGKEGAVRQCTGCNG 167
                     6********************86 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.00083
                     --SSS-S--EE-SSEEE-TTT--EE CS
  zinc-ribbons_6   2 kCpeCqqelekrgeqyhCeaCqedl 26 
                      Cp+Cq e e   e+ +C++C+ + 
      EEA21572.1 187 VCPDCQGEGEILREKDRCKKCNGKK 211
                     5*********9999*******9765 PP

>> Anti-TRAP  Tryptophan RNA-binding attenuator protein inhibitory protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.6      0.08   1.8e+02      29      40 ..     142     153 ..     133     155 .. 0.81
   2 ?    0.6   6.9      0.26   5.8e+02      12      41 ..     145     170 ..     139     174 .. 0.84
   3 ?    9.1   3.8   0.00055       1.2      12      45 ..     161     200 ..     159     202 .. 0.77
   4 ?   12.0   2.7   6.7e-05      0.15      10      42 ..     185     213 ..     174     217 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.08
                 ...E-TTTTTSS CS
   Anti-TRAP  29 asleCPkCsGkg 40 
                  s+ CP C G+g
  EEA21572.1 142 KSVICPGCDGRG 153
                 5788****9987 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.26
                 E-TTTTTTSEETTE......E-TTTTTSSE CS
   Anti-TRAP  12 kCdaCngsGkiepeeprasleCPkCsGkgl 41 
                  C+ C+g G  e++      +C  C+G g+
  EEA21572.1 145 ICPGCDGRGGKEGA----VRQCTGCNGSGM 170
                 59999999999888....678999999886 PP

  == domain 3  score: 9.1 bits;  conditional E-value: 0.00055
                 E-TTTTTTSEETTE............E-TTTTTSSEEE-H CS
   Anti-TRAP  12 kCdaCngsGkiepe......eprasleCPkCsGkglipTa 45 
                 +C  CngsG            +r    CP+C+G+g i+ +
  EEA21572.1 161 QCTGCNGSGMKTMMrqmgpmIQRFQTVCPDCQGEGEILRE 200
                 7********887774444445566778********98865 PP

  == domain 4  score: 12.0 bits;  conditional E-value: 6.7e-05
                 EEE-TTTTTTSEETTE......E-TTTTTSSEE CS
   Anti-TRAP  10 EtkCdaCngsGkiepeeprasleCPkCsGkgli 42 
                  t C+ C+g G+i  e       C kC+Gk+ i
  EEA21572.1 185 QTVCPDCQGEGEILRE----KDRCKKCNGKKTI 213
                 689**********999....447*******988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (410 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       674  (0.0375927); expected 358.6 (0.02)
Passed bias filter:                      506  (0.0282224); expected 358.6 (0.02)
Passed Vit filter:                        67  (0.00373696); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.77u 0.36s 00:00:01.12 Elapsed: 00:00:00.61
# Mc/sec: 2011.53
//
Query:       EEA21573.1  [L=834]
Description: sulfate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   9.9e-109  363.6  21.0   1.3e-108  363.1  21.0    1.2  1  Sulfate_transp  Sulfate permease family
    4.4e-08   32.8   0.0    1.4e-07   31.2   0.0    1.7  2  STAS            STAS domain
     0.0012   19.2   2.3     0.0012   19.2   2.3    3.6  3  MFS_MOT1        Molybdate transporter of MFS superfamily


Domain annotation for each model (and alignments):
>> Sulfate_transp  Sulfate permease family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  363.1  21.0  2.2e-112  1.3e-108       1     379 [.      91     480 ..      91     481 .. 0.96

  Alignments for each domain:
  == domain 1  score: 363.1 bits;  conditional E-value: 2.2e-112
  Sulfate_transp   1 lkgDliaGitvallaiPqalayallaglppiygLyssvvpqlvyalfGtsrqlavGpvavlslivgeiiakvaeeepek.gieiattltllaGvi 94 
                     ++gDl+aGitv+++ +Pq+++ya+la+lp++ygLyss+++ l+y++f+ts+++++Gpvav+s+++g+++  v +e+pe  +  ia++l++++G+i
      EEA21573.1  91 FIGDLVAGITVGAVVVPQGMSYAQLADLPVEYGLYSSFMGVLIYWFFATSKDITIGPVAVMSTLTGNVVIAVRKEHPELpAQVIASALAIISGAI 185
                     89**********************************************************************77776651567899********* PP

  Sulfate_transp  95 qvllGllRLgflveflseavlsGfiaGaaivillsqikvllgle.rvskkeslvsvlsslftnlekvnlakvvlgllllvvLlvtkellkklkkl 188
                       ++Gl+R g++vef++ +++++f++G+a++i+  qik+llg + ++++++ +++++++ ++ l+ ++ ++++lgl++l++L+ +++ ++    +
      EEA21573.1 186 ITFIGLIRWGWIVEFIPLTAITAFMTGSALNIASGQIKNLLGETvNFNTRGATYQNVINSLKYLPSAQ-VDAALGLTALFMLYAIRSACNYGARK 279
                     ******************************************************************99.9****************998854444 PP

  Sulfate_transp 189 ........lvipapaelvavivatlvsaifelkreag..vkivgeipsglpelslpkvdwsllsallpdalaialvglleaiavsksldkkkgyk 273
                             ++i++ + +++++++t++sa+++ +r+++  +k++g +p+g+++  +p +d+s++++ ++ +++  +v l+e+i++sks++++++y+
      EEA21573.1 280 rpqraktfFFISTLRTVFVILFYTMISAAVNIHRRKNpaFKVIGVVPRGFKHAAVPTIDVSIIQSFISYLPSAVIVLLIEHISISKSFGRVNNYT 374
                     78999999**********************777776622568***************************************************** PP

  Sulfate_transp 274 vdsnkELvAlGfsNilsslfgglpatgafsrsavnikaGaktqlsglvsalvvllvllvltplleyiPkavLaaiiivagkglLvelkelkklwk 368
                     +d+ +E+vA+G++N+l++++g++patg+fsr+a++ kaG++t+l+gl++a+vvll++++l+pl+ yiP+a+L+a+ii+a+ +l++  + ++++w 
      EEA21573.1 375 IDPSQEMVAIGVTNLLGPFLGAYPATGSFSRTAIKSKAGVRTPLAGLITAIVVLLAIYALPPLFWYIPQAALSAVIIHAVGDLITPPNVVYQFWL 469
                     **********************************************************************************99999999***** PP

  Sulfate_transp 369 lskldflilla 379
                     +s+l++++++a
      EEA21573.1 470 VSPLEVVVFFA 480
                     ********986 PP

>> STAS  STAS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0      0.89   5.3e+03      57      71 ..     333     347 ..     330     349 .. 0.86
   2 !   31.2   0.0   2.3e-11   1.4e-07       7      77 ..     580     677 ..     576     706 .. 0.89

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 0.89
                 EEEEE-HHHHHHHHH CS
        STAS  57 avsfiDssGvraLke 71 
                 av+ iD+s ++++++
  EEA21573.1 333 AVPTIDVSIIQSFIS 347
                 899*****9999875 PP

  == domain 2  score: 31.2 bits;  conditional E-value: 2.3e-11
                 CTTEEEEEEEEEESHHHHHHHHHHHHHHHHCCC...................................-SEEEEEEEEEEEE-HHHHHHHHHHHHHHH CS
        STAS   7 iegililrldgpidfanaesfkeklkravgeeperve...........................kkeslkslildlsavsfiDssGvraLkeilkelk 77 
                 ++g+ i+r+++ + + na+s ++ l +++ +e++r +                               l+ +ild+s v+++D+++++ L++++++l 
  EEA21573.1 580 YPGVFIYRFSEGFVYPNANSETDYLVQTIFKETRRTNiesyptlgdrpwndpgprrgmpvqdksHLPTLRAIILDFSSVDHVDVTSIQNLIDVRNQLD 677
                 589*****************************99999************************9999999**************************9985 PP

>> MFS_MOT1  Molybdate transporter of MFS superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.4   4.7    0.0038        23      37     109 ..     127     215 ..      95     217 .. 0.68
   2 ?   -0.2   0.2      0.22   1.3e+03      10      49 ..     258     304 ..     252     358 .. 0.66
   3 !   19.2   2.3     2e-07    0.0012      16     106 ..     350     452 ..     328     457 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.0038
    MFS_MOT1  37 GlmnlltglfggvPmc............hgAgglaaqyrf.....gartgaag..illGlvllllgltgllerllrliPksvlgglllgaGl 109
                 ++m +l+ +f+++               +g  ++a +  +     +a+++a++  i+ G+++ ++gl++   +++++iP + + + + g++l
  EEA21573.1 127 SFMGVLIYWFFATSKDitigpvavmstlTGNVVIAVR--KehpelPAQVIASAlaIISGAIITFIGLIR-WGWIVEFIPLTAITAFMTGSAL 215
                 4555555555554333333344466643444444544..3358998898888623688**********9.79************99999887 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.22
    MFS_MOT1  10 lglTllnlvialaala........slsltalllsvGlmnlltglfggv 49 
                 lglT l ++ a+ + +        +  ++++++++ l ++++ lf+ +
  EEA21573.1 258 LGLTALFMLYAIRSACnygarkrpQ-RAKTFFFISTLRTVFVILFYTM 304
                 7888888888888888888888743.4666666667777777777776 PP

  == domain 3  score: 19.2 bits;  conditional E-value: 2e-07
    MFS_MOT1  16 nlvialaala..............slsltalllsvGlmnlltglfggvPmc.hgAgglaaqyrfgartgaagillGlvllllgltgllerllrliPksv 99 
                 ++++ + +++              ++++++ ++ +G+ nll+ ++g+ P     +  ++   + g rt  ag+++++v+ll ++  +l  l ++iP++ 
  EEA21573.1 350 PSAVIVLLIEhisisksfgrvnnyTIDPSQEMVAIGVTNLLGPFLGAYPATgSFSRTAIKS-KAGVRTPLAGLITAIVVLL-AIY-ALPPLFWYIPQAA 445
                 44444444445666777788888899************************98999999998.77**********9988765.444.69*********** PP

    MFS_MOT1 100 lgglllg 106
                 l ++++ 
  EEA21573.1 446 LSAVIIH 452
                 9998775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (834 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       729  (0.0406604); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.83u 0.36s 00:00:01.19 Elapsed: 00:00:00.57
# Mc/sec: 4405.44
//
Query:       EEA21574.1  [L=298]
Description: RTA1 domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.3e-54  182.7  14.4    6.3e-54  182.7  14.4    1.8  2  RTA1      RTA1 like protein


Domain annotation for each model (and alignments):
>> RTA1  RTA1 like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.6     0.025   4.4e+02      33     140 ..      12      49 ..       2      57 .. 0.48
   2 !  182.7  14.4   3.5e-58   6.3e-54       1     202 [.      54     262 ..      54     266 .. 0.96

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.025
        RTA1  33 qivllllaPafiaaaiYmllgrlilllgeelsllrpklytkiFvvlDvvslllqaaGGglaasasssaeaklGeniiiaGlalQvvvlvvFlllaldFl 131
                 +  l +  P + aa i++ll   ++                                                                      +  +
  EEA21574.1  12 NYYLWYYVPSLPAAIIFLLLFIAAT----------------------------------------------------------------------TLHI 40 
                 5555555555555555555544444......................................................................4444 PP

        RTA1 132 lrvrkskkf 140
                 +r+ k++++
  EEA21574.1  41 YRLFKTRTW 49 
                 444433333 PP

  == domain 2  score: 182.7 bits;  conditional E-value: 3.5e-58
        RTA1   1 lilGcileviGYigRilsakntskaslgpfiiqivllllaPafiaaaiYmllgrlilll.geelsllrpklytkiFvvlDvvslllqaaGGglaasass 98 
                 +++G+i+e+ G igR+ +++n  +asl  +++    +llaPa++aa+iYm+lgrl+++l +e+lsl++ +++tkiFv++Dv+s+++q++  gl+ + ++
  EEA21574.1  54 FAIGGIFEIYGLIGRCTANRN--TASLFSYALANNGILLAPALFAASIYMTLGRLLRFLhAEHLSLINVQWLTKIFVIGDVLSFAVQGSSVGLSITGHD 150
                 689******************..678*********************************************************************9977 PP

        RTA1  99 saeaklGeniiiaGlalQvvvlvvFlllaldFllrvr............kskkfkkfllalyaavlliliRsiyRvvElaeGwdgylithEvyfyvLda 185
                       ++ +ii+Gl++Q++++++F+++++ F++rv+            +  ++ k+l++ly ++ li+iRs++R+vE+++G +gyl++hE+++yv+d 
  EEA21574.1 151 V----GAKAVIIVGLLIQIISFGLFGITTVAFYRRVSsssstlatpsgkHGLEWMKILYMLYYTSGLIMIRSVFRLVEYIMGNNGYLLRHEWTMYVFDV 245
                 4....47899**************************************96678********************************************** PP

        RTA1 186 llillavvllnvfhpgr 202
                 +l++ ++ ++ v++p+ 
  EEA21574.1 246 VLMVGVMGIFYVWYPSS 262
                 ***************76 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (298 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       632  (0.0352502); expected 358.6 (0.02)
Passed bias filter:                      262  (0.0146132); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.30s 00:00:00.86 Elapsed: 00:00:00.53
# Mc/sec: 1685.34
//
Query:       EEA21575.1  [L=403]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.9e-08   33.3  10.8    6.2e-08   32.6  10.8    1.3  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.6  10.8   3.5e-12   6.2e-08       2      37 ..      12      46 ..      11      47 .. 0.94

  Alignments for each domain:
  == domain 1  score: 32.6 bits;  conditional E-value: 3.5e-12
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfysess 37
                +C+ C++++vKCd+  P+CsnC+  n +C+ y+ s+
  EEA21575.1 12 GCIVCKRRHVKCDESYPTCSNCRDANRHCE-YQVSK 46
                7*****************************.98875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (403 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       607  (0.0338558); expected 358.6 (0.02)
Passed bias filter:                      381  (0.0212505); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.33s 00:00:00.95 Elapsed: 00:00:00.55
# Mc/sec: 2197.49
//
Query:       EEA21576.1  [L=152]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-22   79.4   2.6    3.2e-22   78.9   2.6    1.2  1  Rab5ip    Rab5-interacting protein (Rab5ip)


Domain annotation for each model (and alignments):
>> Rab5ip  Rab5-interacting protein (Rab5ip)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.9   2.6   1.8e-26   3.2e-22       1      79 [.      26     145 ..      26     147 .. 0.92

  Alignments for each domain:
  == domain 1  score: 78.9 bits;  conditional E-value: 1.8e-26
      Rab5ip   1 vlsnlrsltalllGvvaGilgLeslsGflfylllsllvsllfyalkvkgkskk.......yfrg................................alk 60 
                 vls+lrslta++lG++aGilgL+s++Gf+fy++++llvs l+ +l+++++s++       y++g                                a++
  EEA21576.1  26 VLSQLRSLTAFILGISAGILGLQSTAGFAFYFAGTLLVSGLVQFLLLGPSSSSstggagaYYPGasggeiegiddfgkirarggsqgqgkpiqrkgAWR 124
                 699****************************************999**999776666777777799999999999999999999999999999999*** PP

      Rab5ip  61 elwteglvn..glagFvLtWt 79 
                 ++w++g v+  +l+gFvL+W+
  EEA21576.1 125 DVWLGGGVMgeALSGFVLGWA 145
                 *****9998899********7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (152 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       420  (0.0234257); expected 358.6 (0.02)
Passed bias filter:                      273  (0.0152267); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 1091.76
//
Query:       EEA21577.1  [L=614]
Description: SAM domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-07   30.8   0.1    5.6e-07   29.6   0.1    1.6  1  SAM_2     SAM domain (Sterile alpha motif)
     0.0017   18.8   0.2     0.0036   17.7   0.2    1.6  1  SAM_1     SAM domain (Sterile alpha motif)
  ------ inclusion threshold ------
       0.11   12.8   0.2       0.27   11.5   0.2    1.6  1  DUF4508   Domain of unknown function (DUF4508)
       0.26    9.9   3.4       0.49    9.0   3.4    1.4  1  DHC_N1    Dynein heavy chain, N-terminal region 1


Domain annotation for each model (and alignments):
>> SAM_2  SAM domain (Sterile alpha motif)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.6   0.1   1.3e-10   5.6e-07       6      66 .]     545     602 ..     541     602 .. 0.94

  Alignments for each domain:
  == domain 1  score: 29.6 bits;  conditional E-value: 1.3e-10
                 HHHHHHHHHHTTTGGGHHHHHHTTCSHHHHHTTSCHHHHHHTTHHHHHHHHHHHHHHHHHH CS
       SAM_2   6 ledvaeWLrsiglkqytdnFrdagitgaelllrlteedLkrlGitsvghrkkilkkiqelk 66 
                 l+d+  WLrs++l++ytdn++d ++t    l +l+ + L++ G++++g r+k+lk ++++k
  EEA21577.1 545 LKDIPAWLRSLRLHKYTDNLKDLKWTD---LIELDDKGLEDRGVNALGARNKMLKVFEQVK 602
                 67999**********************...88***********************998875 PP

>> SAM_1  SAM domain (Sterile alpha motif)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.2   8.1e-07    0.0036       7      58 ..     547     596 ..     545     602 .. 0.90

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 8.1e-07
                 SHHHHHHHTTSGGGHHHHHTTTSSHHHHTTSCHHHHHHCTTTSHHHHHHHHH CS
       SAM_1   7 dVgeWLesiglgqYadlFrageidgdaLlllteddLeklgvtllGHrkkIly 58 
                 d+  WL+s++l++Y+d++++ +  +  L +l+++ Le+ gv+ lG r k+l+
  EEA21577.1 547 DIPAWLRSLRLHKYTDNLKDLK--WTDLIELDDKGLEDRGVNALGARNKMLK 596
                 7889**************7777..999***********************97 PP

>> DUF4508  Domain of unknown function (DUF4508)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.2   5.9e-05      0.27       3      47 ..     108     152 ..     106     159 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 5.9e-05
     DUF4508   3 elryvlqWfkewselqredFlevlveklvkkkvnglldsleslev 47 
                 el  + qWf+  se++r   l+ l++++++ +++  ++ l+++  
  EEA21577.1 108 ELSAIEQWFRVLSEAERTAALYALLQQTTQVQIRFFIQVLQQMAK 152
                 788999*************************99999999988854 PP

>> DHC_N1  Dynein heavy chain, N-terminal region 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   3.4   0.00011      0.49     273     344 ..      70     139 ..      33     156 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00011
      DHC_N1 273 ksydvLdvsaeefeadfkeFkerikdlerrlqaiinqaf.edasslesalellrkfesllerpkikaaleeky 344
                    d Ld+ a+++ ad+++F++    le++ +a i+q f +++s +e+ + +l   e  +   ++ ++ ++ +
  EEA21577.1  70 NADDALDQAAQQWIADIDQFETT---LEEMAAATIDQDFkDELSAIEQWFRVLSEAERTAALYALLQQTTQVQ 139
                 56699****************85...88999********5568888998888887775554444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (614 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       702  (0.0391544); expected 358.6 (0.02)
Passed bias filter:                      436  (0.0243181); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.66u 0.30s 00:00:00.96 Elapsed: 00:00:00.48
# Mc/sec: 3824.36
//
Query:       EEA21578.1  [L=1127]
Description: RNA polymerase III transcription factor TFIIIC subunit (Tfc4), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-18   67.5  16.4    6.1e-07   29.9   0.0    8.7 10  TPR_19           Tetratricopeptide repeat
    2.5e-16   58.9  25.2     0.0027   18.4   1.4   11.4 11  TPR_14           Tetratricopeptide repeat
    1.2e-11   43.7  16.6      0.026   14.5   0.0    8.6  8  TPR_7            Tetratricopeptide repeat
    2.5e-09   36.5  29.3     0.0094   15.7   0.0    9.3  9  TPR_1            Tetratricopeptide repeat
    2.6e-09   36.5  43.3        0.1   12.7   0.1   11.2 12  TPR_2            Tetratricopeptide repeat
    2.2e-08   34.2  24.3      0.017   15.4   0.0    7.8  7  TPR_12           Tetratricopeptide repeat
    1.7e-07   30.9  27.6     0.0042   17.2   0.0    8.5  9  TPR_8            Tetratricopeptide repeat
    1.3e-06   27.9  14.9       0.35   10.6   0.8    7.4  9  TPR_11           TPR repeat
    1.9e-06   28.4   0.0    1.9e-06   28.4   0.0    8.0  7  TPR_16           Tetratricopeptide repeat
    6.6e-06   26.3  20.6       0.16   12.3   1.6    6.8  8  ANAPC3           Anaphase-promoting complex, cyclosome, subun
    7.5e-05   22.5   4.8      0.057   13.1   0.1    4.8  5  RPN7             26S proteasome subunit RPN7
     0.0014   18.7   9.9       0.21   11.8   0.1    5.7  6  TPR_9            Tetratricopeptide repeat
      0.002   18.3  20.7       0.48   10.9   0.2    8.6  9  TPR_17           Tetratricopeptide repeat
     0.0042   16.5   5.0         14    4.9   0.1    5.2  6  TPR_MalT         MalT-like TPR region
     0.0048   17.3   1.3       0.66   10.4   0.0    3.1  3  Alkyl_sulf_dimr  Alkyl sulfatase dimerisation
  ------ inclusion threshold ------
      0.014   15.8   5.5       0.04   14.3   0.6    3.5  3  BTAD             Bacterial transcriptional activator domain
      0.015   15.6   1.9         31    5.0   0.0    4.3  3  TPR_20           Tetratricopeptide repeat
      0.073   12.1   0.0       0.61    9.0   0.0    2.3  3  ChAPs            ChAPs (Chs5p-Arf1p-binding proteins)
       0.41   11.4  18.5         19    6.2   0.0    7.8  6  TPR_6            Tetratricopeptide repeat
        2.1    6.5   5.7        1.3    7.2   3.8    1.5  2  CDC45            CDC45-like protein


Domain annotation for each model (and alignments):
>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.9   0.0   6.8e-10   6.1e-07       2      68 .]     194     260 ..     193     260 .. 0.96
   2 ?   -1.9   0.0       5.7   5.1e+03      14      39 ..     280     305 ..     279     307 .. 0.89
   3 !   15.4   0.1   2.3e-05     0.021       9      46 ..     309     346 ..     305     354 .. 0.93
   4 ?    5.4   0.2     0.029        26      23      55 ..     488     520 ..     465     534 .. 0.76
   5 ?    6.6   0.1     0.012        11       3      55 ..     502     555 ..     500     561 .. 0.88
   6 ?    5.8   0.5     0.022        19      19      46 ..     553     580 ..     529     596 .. 0.82
   7 ?    2.3   0.0      0.27   2.4e+02      26      54 ..     757     785 ..     756     790 .. 0.89
   8 !    9.1   0.1    0.0021       1.9      10      37 ..     944     971 ..     943     979 .. 0.92
   9 ?   -0.1   0.0       1.5   1.4e+03      23      53 ..    1025    1055 ..    1020    1059 .. 0.85
  10 ?   -0.5   0.1         2   1.8e+03      25      49 ..    1098    1122 ..    1085    1125 .. 0.83

  Alignments for each domain:
  == domain 1  score: 29.9 bits;  conditional E-value: 6.8e-10
      TPR_19   2 laegdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpddaryasLlAkl 68 
                 + +gdy++A++l +qa+  +p++ +a  lL e+ la g+ d+A  +L       p d+ ++   A+l
  EEA21578.1 194 FIDGDYDRAIELVQQAILVNPEMFAAHSLLSEIFLARGEKDKAVTALFSGAHTRPRDPTVWYKVARL 260
                 678*********************************************************9999986 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 5.7
      TPR_19  14 leqalqedpknaearllLAeallalg 39 
                 ++++++ d k+ +ar + A a+ +lg
  EEA21578.1 280 YSRIIEIDGKSYNARFQRAAAYRELG 305
                 678899999*9*****9999999987 PP

  == domain 3  score: 15.4 bits;  conditional E-value: 2.3e-05
      TPR_19   9 eAlalleqalqedpknaearllLAeallalgqldeAea 46 
                 +A+  +e++l+e p+n +a+  LAe ++ + ++ +A +
  EEA21578.1 309 RAAGEYERILKELPHNIRALRHLAETYIDMQDVHKALE 346
                 68999***************************999987 PP

  == domain 4  score: 5.4 bits;  conditional E-value: 0.029
      TPR_19  23 knaearllLAeallalgqldeAealLdalpeed 55 
                 ++a++    A+al  +g ++eA +   +l++ +
  EEA21578.1 488 DYADLYREAADALKDAGLFKEALRFYRPLQLTE 520
                 39999******************9998888766 PP

  == domain 5  score: 6.6 bits;  conditional E-value: 0.012
      TPR_19   3 aegdyaeAlalleqa.lqedpknaearllLAeallalgqldeAealLdalpeed 55 
                 ++g + eAl++++ + l+ed  +    l++ e+ +a  +l  Ae +  ++ e d
  EEA21578.1 502 DAGLFKEALRFYRPLqLTEDYADVSFFLAMGECAFACSDLSLAESCYLTVAEND 555
                 578899********88899999999999****************9988888776 PP

  == domain 6  score: 5.8 bits;  conditional E-value: 0.022
      TPR_19  19 qedpknaearllLAeallalgqldeAea 46 
                 + d  n+  r +LA+++  +g+ d+A  
  EEA21578.1 553 ENDSANLQSRVNLAKLYETMGERDQALY 580
                 557889999*****************75 PP

  == domain 7  score: 2.3 bits;  conditional E-value: 0.27
      TPR_19  26 earllLAeallalgqldeAealLdalpee 54 
                 e+ l +A +   +g+ deA ++L+a+ ++
  EEA21578.1 757 EIFLEYAFVVSGQGDKDEAYDVLAAATDA 785
                 678889999999************99875 PP

  == domain 8  score: 9.1 bits;  conditional E-value: 0.0021
      TPR_19  10 AlalleqalqedpknaearllLAealla 37 
                 Al+++ +a++ dp+n+ ++l  A +++ 
  EEA21578.1 944 ALNYYYRAYALDPENPGILLPIALCYIH 971
                 899***********************96 PP

  == domain 9  score: -0.1 bits;  conditional E-value: 1.5
      TPR_19   23 knaearllLAeallalgqldeAealLdalpe 53  
                  + +e+ +++ +++ +lg l +A+ + ++++e
  EEA21578.1 1025 ERQEVEYNYGRVYHSLGLLHQAIPCYERVLE 1055
                  5679999**************9988888776 PP

  == domain 10  score: -0.5 bits;  conditional E-value: 2
      TPR_19   25 aearllLAeallalgqldeAealLd 49  
                  +ea+ +L +++  +g+l+ A+++ +
  EEA21578.1 1098 PEAAVALQNIYALNGNLAGAREVTE 1122
                  7888889999999999999999866 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   0.0     0.003       2.7      13      43 ..     195     225 ..     186     226 .. 0.88
   2 !    9.2   0.0    0.0028       2.5       2      44 .]     218     260 ..     217     260 .. 0.92
   3 !   18.4   1.4     3e-06    0.0027       3      43 ..     293     333 ..     292     334 .. 0.96
   4 ?   -1.0   0.0         5   4.5e+03       8      29 ..     375     396 ..     373     411 .. 0.76
   5 ?   -0.5   0.0       3.4   3.1e+03       2      27 ..     448     475 ..     447     482 .. 0.77
   6 ?    6.6   0.9     0.019        17       2      37 ..     491     525 ..     490     532 .. 0.81
   7 ?    1.1   0.1       1.1   9.5e+02       7      28 ..     565     586 ..     560     594 .. 0.86
   8 ?    3.0   0.0      0.26   2.3e+02       3      30 ..     758     785 ..     756     791 .. 0.81
   9 !    9.3   0.0    0.0026       2.3       2      38 ..     926     962 ..     925     968 .. 0.90
  10 !    7.7   0.0    0.0083       7.4       5      31 ..    1031    1057 ..    1028    1063 .. 0.89
  11 ?    1.9   0.1      0.58   5.2e+02       1      28 [.    1098    1125 ..    1098    1126 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.003
      TPR_14  13 alGdpdeAiallrralalaPddaeawlllaq 43 
                   Gd+d+Ai+l ++a+  +P+  +a+ ll +
  EEA21578.1 195 IDGDYDRAIELVQQAILVNPEMFAAHSLLSE 225
                 579*******************999988876 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.0028
      TPR_14   2 eallalaeallalGdpdeAiallrralalaPddaeawlllaql 44 
                 +a+ +l e++la+G+ d+A+++l     + P d+++w+  a+l
  EEA21578.1 218 AAHSLLSEIFLARGEKDKAVTALFSGAHTRPRDPTVWYKVARL 260
                 6888999******************9999********988875 PP

  == domain 3  score: 18.4 bits;  conditional E-value: 3e-06
      TPR_14   3 allalaeallalGdpdeAiallrralalaPddaeawlllaq 43 
                 a+ ++a+a+++lG   +A+  ++r+l+  P + +a+++la+
  EEA21578.1 293 ARFQRAAAYRELGYNGRAAGEYERILKELPHNIRALRHLAE 333
                 899************************************97 PP

  == domain 4  score: -1.0 bits;  conditional E-value: 5
      TPR_14   8 aeallalGdpdeAiallrrala 29 
                 ae+++  Gdp++ ++ll  + +
  EEA21578.1 375 AELYAYVGDPRKGLQLLSSVAR 396
                 7889999********9988755 PP

  == domain 5  score: -0.5 bits;  conditional E-value: 3.4
      TPR_14   2 eallalaeallalGd..pdeAiallrra 27 
                 e++ +l+ + l lGd   +eA+a+++++
  EEA21578.1 448 ELRIKLGTFRLKLGDryVEEALAHFEWL 475
                 5677888888889877789999999987 PP

  == domain 6  score: 6.6 bits;  conditional E-value: 0.019
      TPR_14   2 eallalaeallalGdpdeAiallrralalaPddaea 37 
                 ++++++a+al  +G ++eA++ +r + +l  d a++
  EEA21578.1 491 DLYREAADALKDAGLFKEALRFYRPL-QLTEDYADV 525
                 68999******************987.666666655 PP

  == domain 7  score: 1.1 bits;  conditional E-value: 1.1
      TPR_14   7 laeallalGdpdeAiallrral 28 
                 la+++++ G+ d+A+ + ++a+
  EEA21578.1 565 LAKLYETMGERDQALYYVNQAV 586
                 89************98888875 PP

  == domain 8  score: 3.0 bits;  conditional E-value: 0.26
      TPR_14   3 allalaeallalGdpdeAiallrralal 30 
                   l++a +   +Gd deA ++l +a ++
  EEA21578.1 758 IFLEYAFVVSGQGDKDEAYDVLAAATDA 785
                 567888888899************9764 PP

  == domain 9  score: 9.3 bits;  conditional E-value: 0.0026
      TPR_14   2 eallalaeallalGdpdeAiallrralalaPddaeaw 38 
                 ++l +++++l+    +  A++++ ra al+P+++ ++
  EEA21578.1 926 ALLVLYGHILYSGNSFYPALNYYYRAYALDPENPGIL 962
                 577899***************************9876 PP

  == domain 10  score: 7.7 bits;  conditional E-value: 0.0083
      TPR_14    5 lalaeallalGdpdeAiallrralala 31  
                  + +++++  lG + +Ai +++r+l+l+
  EEA21578.1 1031 YNYGRVYHSLGLLHQAIPCYERVLELG 1057
                  5699********************976 PP

  == domain 11  score: 1.9 bits;  conditional E-value: 0.58
      TPR_14    1 peallalaeallalGdpdeAiallrral 28  
                  pea  al  +++ +G++++A+++ +++l
  EEA21578.1 1098 PEAAVALQNIYALNGNLAGAREVTEKYL 1125
                  6788888899************999875 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.2   0.0    0.0066       5.9      12      31 ..     196     213 ..     187     215 .. 0.85
   2 ?    0.8   0.0      0.69   6.2e+02       2      22 ..     220     240 ..     219     252 .. 0.79
   3 ?    4.3   0.2     0.054        48       6      28 ..     298     321 ..     294     325 .. 0.87
   4 !   11.5   0.3   0.00027      0.25       1      29 [.     327     353 ..     327     363 .. 0.87
   5 ?    0.9   0.2      0.65   5.8e+02       6      23 ..     497     514 ..     492     525 .. 0.84
   6 ?   -0.7   0.0       2.2   1.9e+03       3      24 ..     529     550 ..     528     558 .. 0.84
   7 ?    6.4   0.1     0.011        10       3      19 ..     563     579 ..     561     591 .. 0.91
   8 !   14.5   0.0   2.9e-05     0.026       6      31 ..    1034    1059 ..    1031    1065 .. 0.87

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0066
       TPR_7  12 lGdyeeAielyeqsLaltkd 31 
                 +Gdy++Aiel +q  a+   
  EEA21578.1 196 DGDYDRAIELVQQ--AILVN 213
                 59***********..77655 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.69
       TPR_7   2 LlnLarlysrlGdyeeAiely 22 
                 ++ L +++ ++G+ ++A++ +
  EEA21578.1 220 HSLLSEIFLARGEKDKAVTAL 240
                 678999************976 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.054
       TPR_7   6 arlysrlGdyeeAielyeqsL.al 28 
                 a +y++lG+  +A++ ye+ L +l
  EEA21578.1 298 AAAYRELGYNGRAAGEYERILkEL 321
                 789****************87665 PP

  == domain 4  score: 11.5 bits;  conditional E-value: 0.00027
       TPR_7   1 aLlnLarlysrlGdyeeAielyeqsLalt 29 
                 aL  La++y +++d  +A+e+y +  +++
  EEA21578.1 327 ALRHLAETYIDMQDVHKALEYYLA--GIE 353
                 6789******************98..665 PP

  == domain 5  score: 0.9 bits;  conditional E-value: 0.65
       TPR_7   6 arlysrlGdyeeAielye 23 
                 a++  + G ++eA+++y+
  EEA21578.1 497 ADALKDAGLFKEALRFYR 514
                 8899999**********7 PP

  == domain 6  score: -0.7 bits;  conditional E-value: 2.2
       TPR_7   3 lnLarlysrlGdyeeAielyeq 24 
                 l+++++ +++ d + A+++y  
  EEA21578.1 529 LAMGECAFACSDLSLAESCYLT 550
                 78999999************87 PP

  == domain 7  score: 6.4 bits;  conditional E-value: 0.011
       TPR_7   3 lnLarlysrlGdyeeAi 19 
                 +nLa ly+ +G++++A+
  EEA21578.1 563 VNLAKLYETMGERDQAL 579
                 69**************7 PP

  == domain 8  score: 14.5 bits;  conditional E-value: 2.9e-05
       TPR_7    6 arlysrlGdyeeAielyeqsLaltkd 31  
                  +r+y++lG   +Ai +ye++L+l ++
  EEA21578.1 1034 GRVYHSLGLLHQAIPCYERVLELGNQ 1059
                  99*****************9988655 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.9   0.0   0.00073      0.65      13      33 ..     195     215 ..     185     216 .. 0.87
   2 ?   -1.5   0.0       2.9   2.6e+03      21      31 ..     277     287 ..     277     289 .. 0.87
   3 ?   -1.1   0.2       2.2     2e+03       2      15 ..     292     305 ..     291     305 .. 0.87
   4 !    8.7   0.7    0.0018       1.6       2      29 ..     326     353 ..     325     355 .. 0.89
   5 ?    0.2   0.5      0.85   7.6e+02       8      25 ..     497     514 ..     490     514 .. 0.80
   6 ?    0.2   0.0      0.83   7.4e+02       7      27 ..     531     551 ..     527     558 .. 0.84
   7 !    7.7   0.1    0.0037       3.3       6      28 ..     564     586 ..     560     589 .. 0.90
   8 !    6.4   0.5    0.0094       8.4       8      34 .]     932     958 ..     932     958 .. 0.90
   9 !   15.7   0.0     1e-05    0.0094       5      30 ..    1031    1056 ..    1028    1057 .. 0.91

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00073
                 HTT-HHHHHHHHHHHHHHSTT CS
       TPR_1  13 klgkydeAleyyekALelnPn 33 
                   g+yd A+e  ++A+ +nP+
  EEA21578.1 195 IDGDYDRAIELVQQAILVNPE 215
                 569*****************7 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 2.9
                 HHHHHHHHHHS CS
       TPR_1  21 leyyekALeln 31 
                 + +y++ +e++
  EEA21578.1 277 IYCYSRIIEID 287
                 67*******98 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 2.2
                 HHHHHHHHHHHHTT CS
       TPR_1   2 kalynlGnayfklg 15 
                 +a +++++ay++lg
  EEA21578.1 292 NARFQRAAAYRELG 305
                 57899******998 PP

  == domain 4  score: 8.7 bits;  conditional E-value: 0.0018
                 HHHHHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1   2 kalynlGnayfklgkydeAleyyekALe 29 
                 +al  l+ +y  +++  +Aleyy   +e
  EEA21578.1 326 RALRHLAETYIDMQDVHKALEYYLAGIE 353
                 78999******************77666 PP

  == domain 5  score: 0.2 bits;  conditional E-value: 0.85
                 HHHHHHTT-HHHHHHHHH CS
       TPR_1   8 GnayfklgkydeAleyye 25 
                 + a+   g ++eAl +y+
  EEA21578.1 497 ADALKDAGLFKEALRFYR 514
                 678889999******996 PP

  == domain 6  score: 0.2 bits;  conditional E-value: 0.83
                 HHHHHHHTT-HHHHHHHHHHH CS
       TPR_1   7 lGnayfklgkydeAleyyekA 27 
                 +G + f   ++  A+ +y  +
  EEA21578.1 531 MGECAFACSDLSLAESCYLTV 551
                 899***************766 PP

  == domain 7  score: 7.7 bits;  conditional E-value: 0.0037
                 HHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_1   6 nlGnayfklgkydeAleyyekAL 28 
                 nl+ +y  +g+ d+Al y ++A+
  EEA21578.1 564 NLAKLYETMGERDQALYYVNQAV 586
                 9*****************99997 PP

  == domain 8  score: 6.4 bits;  conditional E-value: 0.0094
                 HHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1   8 GnayfklgkydeAleyyekALelnPnn 34 
                 G+++++ + +  Al yy +A  l+P+n
  EEA21578.1 932 GHILYSGNSFYPALNYYYRAYALDPEN 958
                 778888888999*************97 PP

  == domain 9  score: 15.7 bits;  conditional E-value: 1e-05
                  HHHHHHHHHTT-HHHHHHHHHHHHHH CS
       TPR_1    5 ynlGnayfklgkydeAleyyekALel 30  
                  yn G +y++lg + +A+ +ye++Lel
  EEA21578.1 1031 YNYGRVYHSLGLLHQAIPCYERVLEL 1056
                  666899*******************8 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.4   0.0   0.00063      0.56      11      33 ..     193     215 ..     185     216 .. 0.85
   2 ?    1.8   0.0      0.37   3.3e+02       2      23 ..     218     239 ..     217     240 .. 0.90
   3 !    7.3   2.3    0.0064       5.7       3      34 .]     293     324 ..     291     324 .. 0.93
   4 !   11.2   0.4   0.00035      0.31       2      31 ..     326     355 ..     325     357 .. 0.92
   5 ?   -1.4   0.1         4   3.6e+03      17      25 ..     464     473 ..     460     473 .. 0.79
   6 ?    2.7   1.5      0.19   1.7e+02       1      25 [.     490     514 ..     490     514 .. 0.92
   7 ?   -1.4   0.0       3.9   3.5e+03       6      31 ..     530     555 ..     527     558 .. 0.84
   8 !    7.0   0.1    0.0078         7       6      30 ..     564     588 ..     561     591 .. 0.92
   9 ?   -1.9   0.0       5.8   5.2e+03      14      27 ..     769     782 ..     760     784 .. 0.83
  10 ?    2.1   0.5      0.29   2.6e+02       4      34 .]     928     958 ..     925     958 .. 0.84
  11 !   12.7   0.1   0.00012       0.1       5      30 ..    1031    1056 ..    1027    1059 .. 0.93
  12 ?    2.1   0.0      0.29   2.6e+02       9      28 ..    1106    1125 ..    1106    1127 .] 0.88

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00063
       TPR_2  11 yyklgdyeeAleafekAleldPn 33 
                 ++  gdy++A+e+ ++A+  +P+
  EEA21578.1 193 AFIDGDYDRAIELVQQAILVNPE 215
                 6778****************996 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.37
       TPR_2   2 ealynlGlayyklgdyeeAlea 23 
                  a+  l ++ +++g+ ++A+ a
  EEA21578.1 218 AAHSLLSEIFLARGEKDKAVTA 239
                 58999**************976 PP

  == domain 3  score: 7.3 bits;  conditional E-value: 0.0064
       TPR_2   3 alynlGlayyklgdyeeAleafekAleldPnn 34 
                 a ++++ ay++lg   +A+  +e+ l+  P+n
  EEA21578.1 293 ARFQRAAAYRELGYNGRAAGEYERILKELPHN 324
                 6699************************9987 PP

  == domain 4  score: 11.2 bits;  conditional E-value: 0.00035
       TPR_2   2 ealynlGlayyklgdyeeAleafekAleld 31 
                 +al  l++ y+ ++d  +Ale++ + +e++
  EEA21578.1 326 RALRHLAETYIDMQDVHKALEYYLAGIEYY 355
                 6899********************999876 PP

  == domain 5  score: -1.4 bits;  conditional E-value: 4
       TPR_2  17 y.eeAleafe 25 
                 y eeAl++fe
  EEA21578.1 464 YvEEALAHFE 473
                 5599999997 PP

  == domain 6  score: 2.7 bits;  conditional E-value: 0.19
       TPR_2   1 aealynlGlayyklgdyeeAleafe 25 
                 a+++ + ++a+  +g ++eAl++++
  EEA21578.1 490 ADLYREAADALKDAGLFKEALRFYR 514
                 6789999***************996 PP

  == domain 7  score: -1.4 bits;  conditional E-value: 3.9
       TPR_2   6 nlGlayyklgdyeeAleafekAleld 31 
                 ++G+++++  d+  A+ ++  + e d
  EEA21578.1 530 AMGECAFACSDLSLAESCYLTVAEND 555
                 68999999999********9887765 PP

  == domain 8  score: 7.0 bits;  conditional E-value: 0.0078
       TPR_2   6 nlGlayyklgdyeeAleafekAlel 30 
                 nl+++y+ +g+ ++Al + ++A+ l
  EEA21578.1 564 NLAKLYETMGERDQALYYVNQAVLL 588
                 89********************876 PP

  == domain 9  score: -1.9 bits;  conditional E-value: 5.8
       TPR_2  14 lgdyeeAleafekA 27 
                 +gd +eA + + +A
  EEA21578.1 769 QGDKDEAYDVLAAA 782
                 8******9887766 PP

  == domain 10  score: 2.1 bits;  conditional E-value: 0.29
       TPR_2   4 lynlGlayyklgdyeeAleafekAleldPnn 34 
                 l   G ++y  + +  Al+++ +A +ldP+n
  EEA21578.1 928 LVLYGHILYSGNSFYPALNYYYRAYALDPEN 958
                 5667888888888888*************97 PP

  == domain 11  score: 12.7 bits;  conditional E-value: 0.00012
       TPR_2    5 ynlGlayyklgdyeeAleafekAlel 30  
                  yn G++y  lg + +A+ ++e++lel
  EEA21578.1 1031 YNYGRVYHSLGLLHQAIPCYERVLEL 1056
                  9***********************98 PP

  == domain 12  score: 2.1 bits;  conditional E-value: 0.29
       TPR_2    9 layyklgdyeeAleafekAl 28  
                  ++y+ +g+++ A+e  ek l
  EEA21578.1 1106 NIYALNGNLAGAREVTEKYL 1125
                  689***********999866 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.1     0.086        77      16      30 ..     196     210 ..     183     240 .. 0.58
   2 ?    1.2   0.6      0.52   4.6e+02      14      63 ..     268     316 ..     265     321 .. 0.84
   3 !    7.6   0.4    0.0052       4.7       4      36 ..     326     358 ..     323     365 .. 0.77
   4 ?    4.0   0.2     0.066        60      43      68 ..     488     513 ..     448     514 .. 0.57
   5 !   13.3   0.2   8.4e-05     0.076      15      71 ..     530     585 ..     525     588 .. 0.76
   6 ?   -1.3   0.1         3   2.7e+03      53      75 ..     933     955 ..     925     957 .. 0.62
   7 !   15.4   0.0   1.9e-05     0.017       5      40 ..    1029    1064 ..    1025    1068 .. 0.87

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.086
      TPR_12  16 lgrydeAlellekal 30 
                  g+yd A+el ++a+
  EEA21578.1 196 DGDYDRAIELVQQAI 210
                 566666666666664 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.52
      TPR_12  14 rrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryee 63 
                 +r++ + + + ++ + +ei  ++++  + + a+++r Lg   ra+g+ye 
  EEA21578.1 268 NRQKTLNDMIYCYSRIIEIDGKSYNA-RFQRAAAYRELGYNGRAAGEYER 316
                 56777778889999999999999886.899*********99999999986 PP

  == domain 3  score: 7.6 bits;  conditional E-value: 0.0052
      TPR_12   4 talnnlaavlrrlgrydeAlellekaleiarrl 36 
                 +al++la+++  +++ ++Ale++ + +e + +l
  EEA21578.1 326 RALRHLAETYIDMQDVHKALEYYLAGIEYYMSL 358
                 577789999999999999999998777766555 PP

  == domain 4  score: 4.0 bits;  conditional E-value: 0.066
      TPR_12  43 ltattlrnLgrlyralgryeeAlell 68 
                 ++a  +r  ++++  +g ++eAl+++
  EEA21578.1 488 DYADLYREAADALKDAGLFKEALRFY 513
                 34555666666666666666666665 PP

  == domain 5  score: 13.3 bits;  conditional E-value: 8.4e-05
      TPR_12  15 rlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleea 71 
                 ++g+++ A++ l  a   +  + + d+ + ++++ nL+ ly+ +g+ ++Al++ ++a
  EEA21578.1 530 AMGECAFACSDLSLAESCYLTVAENDS-ANLQSRVNLAKLYETMGERDQALYYVNQA 585
                 556666666666666666655555556.679************************99 PP

  == domain 6  score: -1.3 bits;  conditional E-value: 3
      TPR_12  53 rlyralgryeeAlelleealaia 75 
                  +++  + +  Al+++ +a+a++
  EEA21578.1 933 HILYSGNSFYPALNYYYRAYALD 955
                 45555555556888888888876 PP

  == domain 7  score: 15.4 bits;  conditional E-value: 1.9e-05
      TPR_12    5 alnnlaavlrrlgrydeAlellekaleiarrllGpd 40  
                  + +n++ v++ lg +++A+ ++e++le+ ++++ p+
  EEA21578.1 1029 VEYNYGRVYHSLGLLHQAIPCYERVLELGNQIQSPH 1064
                  6789***********************999887775 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0     0.021        19      14      33 ..     196     215 ..     184     216 .. 0.84
   2 ?   -1.8   0.0       5.9   5.3e+03       6      23 ..     222     239 ..     219     240 .. 0.84
   3 ?   -0.8   0.5       2.6   2.4e+03       3      26 ..     293     316 ..     291     319 .. 0.78
   4 !   10.0   0.4   0.00097      0.87       6      30 ..     330     354 ..     325     355 .. 0.88
   5 ?   -1.5   0.2       4.5     4e+03       7      25 ..     496     514 ..     490     514 .. 0.82
   6 !    7.6   0.1    0.0055         5       2      28 ..     560     586 ..     559     588 .. 0.88
   7 ?   -2.0   0.0       6.8   6.1e+03      14      29 ..     769     784 ..     767     786 .. 0.81
   8 ?    3.8   0.2     0.091        82       4      34 .]     928     958 ..     925     958 .. 0.91
   9 !   17.2   0.0   4.7e-06    0.0042       5      30 ..    1031    1056 ..    1029    1057 .. 0.97

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.021
                 TT-HHHHHHHHHHHHHHHHH CS
       TPR_8  14 lgdyeeAkeyyekaleldpd 33 
                  gdy+ A+e  ++a+  +p+
  EEA21578.1 196 DGDYDRAIELVQQAILVNPE 215
                 69*************99996 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 5.9
                 HHHHHHHHTT-HHHHHHH CS
       TPR_8   6 nlgsiylklgdyeeAkey 23 
                 +l+ i l  g++++A+ +
  EEA21578.1 222 LLSEIFLARGEKDKAVTA 239
                 688999999******987 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 2.6
                 HHHHHHHHHHHTT-HHHHHHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAkeyyek 26 
                 a ++ + +y++lg    A   ye+
  EEA21578.1 293 ARFQRAAAYRELGYNGRAAGEYER 316
                 7799999******99888766666 PP

  == domain 4  score: 10.0 bits;  conditional E-value: 0.00097
                 HHHHHHHHTT-HHHHHHHHHHHHHH CS
       TPR_8   6 nlgsiylklgdyeeAkeyyekalel 30 
                 +l+ +y++++d ++A eyy   +e+
  EEA21578.1 330 HLAETYIDMQDVHKALEYYLAGIEY 354
                 79*****************998885 PP

  == domain 5  score: -1.5 bits;  conditional E-value: 4.5
                 HHHHHHHTT-HHHHHHHHH CS
       TPR_8   7 lgsiylklgdyeeAkeyye 25 
                  ++++++ g ++eA  +y+
  EEA21578.1 496 AADALKDAGLFKEALRFYR 514
                 6899999999999999886 PP

  == domain 6  score: 7.6 bits;  conditional E-value: 0.0055
                 CHHHHHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_8   2 eayynlgsiylklgdyeeAkeyyekal 28 
                 ++ +nl+++y+++g+ ++A  y ++a+
  EEA21578.1 560 QSRVNLAKLYETMGERDQALYYVNQAV 586
                 6779***************98888887 PP

  == domain 7  score: -2.0 bits;  conditional E-value: 6.8
                 TT-HHHHHHHHHHHHH CS
       TPR_8  14 lgdyeeAkeyyekale 29 
                 +gd++eA  ++  a++
  EEA21578.1 769 QGDKDEAYDVLAAATD 784
                 79*****998888765 PP

  == domain 8  score: 3.8 bits;  conditional E-value: 0.091
                 HHHHHHHHHHTT-HHHHHHHHHHHHHHHHH. CS
       TPR_8   4 yynlgsiylklgdyeeAkeyyekaleldpdn 34 
                 +++ g+i+ + + +  A  yy +a  ldp+n
  EEA21578.1 928 LVLYGHILYSGNSFYPALNYYYRAYALDPEN 958
                 77899************************86 PP

  == domain 9  score: 17.2 bits;  conditional E-value: 4.7e-06
                  HHHHHHHHHTT-HHHHHHHHHHHHHH CS
       TPR_8    5 ynlgsiylklgdyeeAkeyyekalel 30  
                  yn g++y++lg +++A+ +ye++lel
  EEA21578.1 1031 YNYGRVYHSLGLLHQAIPCYERVLEL 1056
                  89**********************97 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.1       3.7   3.3e+03      20      29 ..     113     122 ..     111     124 .. 0.89
   2 !    8.0   0.0    0.0026       2.3       8      38 ..     197     227 ..     193     231 .. 0.88
   3 ?    1.0   0.0      0.39   3.5e+02       3      33 ..     226     256 ..     225     260 .. 0.88
   4 ?    3.5   0.0     0.064        57      14      42 .]     277     305 ..     271     305 .. 0.94
   5 ?   -3.1   0.2       7.6   6.8e+03       3      22 ..     334     353 ..     324     354 .. 0.80
   6 ?   -2.2   0.1       3.9   3.5e+03      10      13 ..     506     509 ..     488     528 .. 0.51
   7 ?   -0.3   0.0      0.98   8.7e+02      16      42 .]     547     573 ..     536     573 .. 0.85
   8 !   10.6   0.8   0.00039      0.35       1      32 [.     932     963 ..     932     969 .. 0.91
   9 !    7.7   0.0    0.0032       2.9       1      23 [.    1034    1056 ..    1034    1059 .. 0.95

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 3.7
      TPR_11  20 AlkldPdnae 29 
                 A++ dP++++
  EEA21578.1 113 AIRADPEDPD 122
                 999******8 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0026
      TPR_11   8 GkyeeAieaYkkAlkldPdnaeayynLGlay 38 
                 G+y+ Aie  ++A+  +P+   a++ L +++
  EEA21578.1 197 GDYDRAIELVQQAILVNPEMFAAHSLLSEIF 227
                 9***********************9987666 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 0.39
      TPR_11   3 ayyeqGkyeeAieaYkkAlkldPdnaeayyn 33 
                 ++ ++G+ ++A++a+      +P +++++y+
  EEA21578.1 226 IFLARGEKDKAVTALFSGAHTRPRDPTVWYK 256
                 78899999****9999999999999999998 PP

  == domain 4  score: 3.5 bits;  conditional E-value: 0.064
      TPR_11  14 ieaYkkAlkldPdnaeayynLGlayykqG 42 
                 i +Y++ +++d ++ +a + +++ay ++G
  EEA21578.1 277 IYCYSRIIEIDGKSYNARFQRAAAYRELG 305
                 889**********************8887 PP

  == domain 5  score: -3.1 bits;  conditional E-value: 7.6
      TPR_11   3 ayyeqGkyeeAieaYkkAlk 22 
                  y + ++  +A+e Y + ++
  EEA21578.1 334 TYIDMQDVHKALEYYLAGIE 353
                 57788888889998888776 PP

  == domain 6  score: -2.2 bits;  conditional E-value: 3.9
      TPR_11  10 yeeA 13 
                 ++eA
  EEA21578.1 506 FKEA 509
                 3333 PP

  == domain 7  score: -0.3 bits;  conditional E-value: 0.98
      TPR_11  16 aYkkAlkldPdnaeayynLGlayykqG 42 
                 +Y +  + d+ n     nL+++y  +G
  EEA21578.1 547 CYLTVAENDSANLQSRVNLAKLYETMG 573
                 78888888999999999******9998 PP

  == domain 8  score: 10.6 bits;  conditional E-value: 0.00039
      TPR_11   1 GdayyeqGkyeeAieaYkkAlkldPdnaeayy 32 
                 G+++y+ + +  A++ Y +A +ldP+n+ +++
  EEA21578.1 932 GHILYSGNSFYPALNYYYRAYALDPENPGILL 963
                 99**************************9876 PP

  == domain 9  score: 7.7 bits;  conditional E-value: 0.0032
      TPR_11    1 GdayyeqGkyeeAieaYkkAlkl 23  
                  G++y+++G + +Ai +Y++ l+l
  EEA21578.1 1034 GRVYHSLGLLHQAIPCYERVLEL 1056
                  89*******************98 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.4   0.0   2.2e-09   1.9e-06       3      67 ..     189     250 ..     187     251 .. 0.91
   2 ?    3.0   3.1      0.18   1.6e+02       2      59 ..     296     350 ..     295     354 .. 0.90
   3 ?    3.1   0.4      0.17   1.5e+02      33      58 ..     489     514 ..     460     517 .. 0.88
   4 ?    1.7   0.3      0.46   4.1e+02      12      61 ..     540     586 ..     529     596 .. 0.81
   5 ?    0.9   0.1      0.82   7.4e+02      37      68 .]     928     959 ..     920     975 .. 0.66
   6 ?   -0.0   0.0       1.6   1.5e+03      10      26 ..    1040    1056 ..    1024    1059 .. 0.57
   7 ?    1.9   0.0      0.42   3.7e+02      33      61 ..    1097    1125 ..    1092    1127 .] 0.84

  Alignments for each domain:
  == domain 1  score: 28.4 bits;  conditional E-value: 2.2e-09
      TPR_16   3 laraalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAa.alyraalraapda 67 
                 +a++a+  gdyd+A+++ ++a+  +   P+  +A+ ll +++l++g+ ++A+ al+  a    p +
  EEA21578.1 189 QATEAFIDGDYDRAIELVQQAILVN---PEMFAAHSLLSEIFLARGEKDKAVtALFSGA-HTRPRD 250
                 78888999*****************...***************************9987.566655 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.18
      TPR_16   2 alaraalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyra 59 
                 ++a a++++g   +Aa  +e+ lk     P + +Al +l++ +   +++ +A+++y+a
  EEA21578.1 296 QRAAAYRELGYNGRAAGEYERILKEL---PHNIRALRHLAETYIDMQDVHKALEYYLA 350
                 5788999999999*************...************99999999999988876 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.17
      TPR_16  33 aaeAllllgdaalrqgrlaeAaalyr 58 
                  a+ + + +da+  +g ++eA+ +yr
  EEA21578.1 489 YADLYREAADALKDAGLFKEALRFYR 514
                 79999****************99987 PP

  == domain 4  score: 1.7 bits;  conditional E-value: 0.46
      TPR_16  12 dyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraal 61 
                 d   A+  + ++ ++d   +++ +++ +l+ ++   g+ + A+ +++ a+
  EEA21578.1 540 DLSLAESCYLTVAEND---SANLQSRVNLAKLYETMGERDQALYYVNQAV 586
                 5667889999999999...9999999999999999999999997777765 PP

  == domain 5  score: 0.9 bits;  conditional E-value: 0.82
      TPR_16  37 llllgdaalrqgrlaeAaalyraalraapdap 68 
                 l l+g +++  + + +A+ +y +a++ +p +p
  EEA21578.1 928 LVLYGHILYSGNSFYPALNYYYRAYALDPENP 959
                 55666666666666677744445556666655 PP

  == domain 6  score: -0.0 bits;  conditional E-value: 1.6
      TPR_16   10 agdyddAaaaleaalkr 26  
                  +g   +A++ +e++l++
  EEA21578.1 1040 LGLLHQAIPCYERVLEL 1056
                  33445566666666654 PP

  == domain 7  score: 1.9 bits;  conditional E-value: 0.42
      TPR_16   33 aaeAllllgdaalrqgrlaeAaalyraal 61  
                   +eA+ +l ++++ +g+la+A+++ +++l
  EEA21578.1 1097 SPEAAVALQNIYALNGNLAGAREVTEKYL 1125
                  67789999999***********9988876 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.7   0.0   0.00052      0.47      33      80 ..     193     241 ..     179     243 .. 0.89
   2 !   12.3   1.6   0.00017      0.16       2      78 ..     270     347 ..     269     350 .. 0.94
   3 ?    2.0   1.0      0.27   2.4e+02      25      75 ..     491     544 ..     463     551 .. 0.64
   4 ?    1.3   1.1      0.45   4.1e+02       4      77 ..     505     580 ..     502     585 .. 0.67
   5 ?   -1.1   0.0       2.6   2.3e+03      35      61 ..     768     790 ..     758     793 .. 0.73
   6 !    7.0   0.1    0.0077       6.9      26      68 ..     928     971 ..     915     979 .. 0.86
   7 ?    0.3   0.0      0.93   8.3e+02      52      81 ..    1023    1052 ..    1010    1061 .. 0.66
   8 ?   -2.5   0.0       7.2   6.5e+03      19      48 ..    1094    1123 ..    1089    1124 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00052
                 HHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHHH- CS
      ANAPC3  33 lylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaaLe 80 
                  + +g+y+rA+el+++a   n++  +++ l+ +  l+ ++ ++A++aL+
  EEA21578.1 193 AFIDGDYDRAIELVQQAiLVNPEMFAAHSLLSEIFLARGEKDKAVTALF 241
                 5778*************99999999**********************97 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 0.00017
                 TT-HHHHHHHHHHHH.HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHH CS
      ANAPC3   2 qnnyknAiflaerllaaetespedayllAlclylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaa 78 
                 q+ +++ i +++r+ + + +s+++++  A ++ ++g   rA   +++  k+ +++++++  +A+++++++ +++A+  
  EEA21578.1 270 QKTLNDMIYCYSRIIEIDGKSYNARFQRAAAYRELGYNGRAAGEYERIlKELPHNIRALRHLAETYIDMQDVHKALEY 347
                 56678999*******************************************************************976 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.27
                 HHHHH.HHHHHHTT-HHHHHHHHHCTSHHHC-HHHHHHHH..HHHHHTT-HHHH CS
      ANAPC3  25 dayll.AlclylngqykrAyellrkaklnskslgcrylfA..qcllkLkkyeeA 75 
                 d+y   A +l  +g +k+A++++r+++l +    + + +A  +c+++ + +  A
  EEA21578.1 491 DLYREaADALKDAGLFKEALRFYRPLQLTEDYADVSFFLAmgECAFACSDLSLA 544
                 233325777888888**********99888888777777777888887766555 PP

  == domain 4  score: 1.3 bits;  conditional E-value: 0.45
                 -HHHHHHHHHHHH.HHH--HHH.HHHH..HHHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHH CS
      ANAPC3   4 nyknAiflaerllaaetesped.ayll..AlclylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAia 77 
                  +k+A+ ++ +l+   te++ d +++l  ++c +  ++   A   + +  + +s +l++r+ +A+ +  +++ ++A+ 
  EEA21578.1 505 LFKEALRFYRPLQ--LTEDYADvSFFLamGECAFACSDLSLAESCYLTVaENDSANLQSRVNLAKLYETMGERDQALY 580
                 5667777777777..555555522333468888888886666666666666688888999999998888888888876 PP

  == domain 5  score: -1.1 bits;  conditional E-value: 2.6
                 HTT-HHHHHHHHHCTSHHHC-HHHHHH CS
      ANAPC3  35 lngqykrAyellrkaklnskslgcryl 61 
                  +g+ ++Ay++l  a    ++  ++y 
  EEA21578.1 768 GQGDKDEAYDVLAAA----TDASVWYH 790
                 589999999999998....66666665 PP

  == domain 6  score: 7.0 bits;  conditional E-value: 0.0077
                 HHHHHHHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHH CS
      ANAPC3  26 ayllAlclylngqykrAyellrka.klnskslgcrylfAqcllk 68 
                 + l++  ly+ + ++ A++++ +a  l+++++g+++ +A c++ 
  EEA21578.1 928 LVLYGHILYSGNSFYPALNYYYRAyALDPENPGILLPIALCYIH 971
                 6789*************************************985 PP

  == domain 7  score: 0.3 bits;  conditional E-value: 0.93
                  HHC-HHHHHHHHHHHHHTT-HHHHHHHH-S CS
      ANAPC3   52 nskslgcrylfAqcllkLkkyeeAiaaLek 81  
                   s+ +++ y +++++  L+ +++Ai ++e+
  EEA21578.1 1023 LSERQEVEYNYGRVYHSLGLLHQAIPCYER 1052
                  455556667777777777777777766554 PP

  == domain 8  score: -2.5 bits;  conditional E-value: 7.2
                  HH--HHHHHHHHHHHHHTT-HHHHHHHHHC CS
      ANAPC3   19 etespedayllAlclylngqykrAyellrk 48  
                  e  spe+a +l   + lng+   A e+++k
  EEA21578.1 1094 EDFSPEAAVALQNIYALNGNLAGAREVTEK 1123
                  66799999999999***9999988888776 PP

>> RPN7  26S proteasome subunit RPN7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0       1.9   1.7e+03      32      59 ..     213     240 ..     200     245 .. 0.86
   2 !   13.1   0.1   6.4e-05     0.057      37      88 ..     326     377 ..     322     384 .. 0.91
   3 ?    0.7   0.1      0.41   3.7e+02      26      94 ..     480     546 ..     477     572 .. 0.73
   4 ?    2.2   0.1      0.15   1.3e+02      37      62 ..     560     585 ..     551     587 .. 0.86
   5 ?    3.7   0.0     0.051        46      33      64 ..    1024    1055 ..    1002    1062 .. 0.80

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 1.9
                 HHHHHHHHHHHHHHHHHCT-HHHHHHHH CS
        RPN7  32 keeirrakldlaehYlkigdleeAlkay 59 
                   e+ +a+  l e +l  g++++A+ a+
  EEA21578.1 213 NPEMFAAHSLLSEIFLARGEKDKAVTAL 240
                 55777899999*************9876 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 6.4e-05
                 HHHHHHHHHHHHCT-HHHHHHHHHTCCCC--SHHHHHHHHHHHHHHHHHTT- CS
        RPN7  37 rakldlaehYlkigdleeAlkaysrireyctslkhkidmllnlirvaiffnd 88 
                 ra   lae Y+++ d+ +Al++y + +ey +sl++  +m +++  v+i+++ 
  EEA21578.1 326 RALRHLAETYIDMQDVHKALEYYLAGIEYYMSLDNDENMEFSWSDVNICAEL 377
                 567899******************************************9875 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 0.41
                 HHHTT-HHHHHHHHHHHHHHHHHCT-HHHHHHHHHTCCCC--SHHHHHHHHHHHHHHHHHTT-HHHHHH CS
        RPN7  26 akenlgkeeirrakldlaehYlkigdleeAlkaysrireyctslkhkidmllnlirvaiffndwdlvsk 94 
                   en++  + ++++ + a+   ++g ++eAl+ y+ +  ++t   + ++ +l++ + a++  d +l+++
  EEA21578.1 480 DSENSTVFDYADLYREAADALKDAGLFKEALRFYRPL--QLTEDYADVSFFLAMGECAFACSDLSLAES 546
                 56888899999999999****************9976..666666677777777777777777766655 PP

  == domain 4  score: 2.2 bits;  conditional E-value: 0.15
                 HHHHHHHHHHHHCT-HHHHHHHHHTC CS
        RPN7  37 rakldlaehYlkigdleeAlkaysri 62 
                 +   +la+ Y ++g++++Al +++++
  EEA21578.1 560 QSRVNLAKLYETMGERDQALYYVNQA 585
                 66789***************999986 PP

  == domain 5  score: 3.7 bits;  conditional E-value: 0.051
                  HHHHHHHHHHHHHHHHCT-HHHHHHHHHTCCC CS
        RPN7   33 eeirrakldlaehYlkigdleeAlkaysrire 64  
                  +e ++  ++ ++ Y++ g l +A+ +y+r++e
  EEA21578.1 1024 SERQEVEYNYGRVYHSLGLLHQAIPCYERVLE 1055
                  45667788999******************987 PP

>> TPR_9  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0      0.19   1.7e+02      10      64 ..     198     252 ..     195     260 .. 0.84
   2 !   11.8   0.1   0.00023      0.21      10      66 ..     272     328 ..     267     333 .. 0.88
   3 ?    5.9   0.1     0.016        14      13      51 ..     309     347 ..     307     359 .. 0.88
   4 ?   -1.0   0.7       2.2   1.9e+03      24      63 ..     554     593 ..     534     609 .. 0.71
   5 ?   -1.4   0.0       3.1   2.8e+03      13      41 ..     943     971 ..     934     972 .. 0.84
   6 ?    4.7   0.0     0.038        34      34      58 ..    1032    1056 ..    1022    1067 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.19
       TPR_9  10 dweralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalapdapd 64 
                 d++ra++ v+  +l++P+    +     +   +G   +A+ +L   ++  p +p+
  EEA21578.1 198 DYDRAIELVQQAILVNPEMFAAHSLLSEIFLARGEKDKAVTALFSGAHTRPRDPT 252
                 89****************9998888888888888888888888777777777665 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 0.00023
       TPR_9  10 dweralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalapdapdae 66 
                     ++ ++ r++ ++ ++   r+ R+ ++ +lG    A+ + e+ l   p++  a 
  EEA21578.1 272 TLNDMIYCYSRIIEIDGKSYNARFQRAAAYRELGYNGRAAGEYERILKELPHNIRAL 328
                 56678889****************************************999776654 PP

  == domain 3  score: 5.9 bits;  conditional E-value: 0.016
       TPR_9  13 ralavverllllaPddpeerrdRGlllaqlGclsaAlad 51 
                 ra   +er+l   P+ ++ +r  +  +  + ++++Al+ 
  EEA21578.1 309 RAAGEYERILKELPHNIRALRHLAETYIDMQDVHKALEY 347
                 5666689****************************9875 PP

  == domain 4  score: -1.0 bits;  conditional E-value: 2.2
       TPR_9  24 laPddpeerrdRGlllaqlGclsaAladLeaylalapdap 63 
                  ++   + r   + l++ +G   +Al   ++++ l  +a+
  EEA21578.1 554 NDSANLQSRVNLAKLYETMGERDQALYYVNQAVLLGREAR 593
                 5666667788889999999999999999999886665444 PP

  == domain 5  score: -1.4 bits;  conditional E-value: 3.1
       TPR_9  13 ralavverllllaPddpeerrdRGlllaq 41 
                  al ++ r  +l+P+ p+ ++  +l++ +
  EEA21578.1 943 PALNYYYRAYALDPENPGILLPIALCYIH 971
                 68999999999***999998888888865 PP

  == domain 6  score: 4.7 bits;  conditional E-value: 0.038
       TPR_9   34 dRGlllaqlGclsaAladLeaylal 58  
                    G++++ lG l++A+ + e+ l+l
  EEA21578.1 1032 NYGRVYHSLGLLHQAIPCYERVLEL 1056
                  679******************9976 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0       0.6   5.4e+02       3      33 ..     207     237 ..     205     238 .. 0.91
   2 ?   -1.2   0.0         4   3.6e+03      10      28 ..     248     267 ..     246     271 .. 0.74
   3 !    8.4   0.1    0.0033         3       1      27 [.     279     305 ..     279     311 .. 0.92
   4 ?    3.6   0.0      0.12     1e+02       2      33 ..     314     345 ..     313     346 .. 0.91
   5 ?   -1.5   0.2       4.8   4.3e+03      11      33 ..     488     510 ..     488     511 .. 0.85
   6 !   10.9   0.2   0.00054      0.48       1      33 [.     547     579 ..     547     580 .. 0.94
   7 ?   -1.4   0.1       4.5     4e+03      16      23 ..     947     954 ..     943     968 .. 0.73
   8 ?   -0.6   0.1       2.6   2.3e+03      17      32 ..    1031    1046 ..    1031    1047 .. 0.76
   9 ?   -1.6   0.0       5.4   4.8e+03      21      34 .]    1106    1119 ..    1102    1119 .. 0.90

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.6
      TPR_17   3 lkaleldPnnadaynnLAelllknGdlmtAr 33 
                 ++a+  +P  + a+ +L e++l +G++++A+
  EEA21578.1 207 QQAILVNPEMFAAHSLLSEIFLARGEKDKAV 237
                 789999999999***************9995 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 4
      TPR_17  10 PnnadaynnLAelll.knGd 28 
                 P ++ +++  A+l   ++G+
  EEA21578.1 248 PRDPTVWYKVARLIQdRAGE 267
                 899******99975425565 PP

  == domain 3  score: 8.4 bits;  conditional E-value: 0.0033
      TPR_17   1 lylkaleldPnnadaynnLAelllknG 27 
                 +y + +e+d ++ +a +++A +++++G
  EEA21578.1 279 CYSRIIEIDGKSYNARFQRAAAYRELG 305
                 799********************9887 PP

  == domain 4  score: 3.6 bits;  conditional E-value: 0.12
      TPR_17   2 ylkaleldPnnadaynnLAelllknGdlmtAr 33 
                 y++ l+  P n  a+  LAe++    d  +A+
  EEA21578.1 314 YERILKELPHNIRALRHLAETYIDMQDVHKAL 345
                 99********************9999988886 PP

  == domain 5  score: -1.5 bits;  conditional E-value: 4.8
      TPR_17  11 nnadaynnLAelllknGdlmtAr 33 
                 ++ad+y + A +l+ +G +++A+
  EEA21578.1 488 DYADLYREAADALKDAGLFKEAL 510
                 57999999999999999888885 PP

  == domain 6  score: 10.9 bits;  conditional E-value: 0.00054
      TPR_17   1 lylkaleldPnnadaynnLAelllknGdlmtAr 33 
                 +yl ++e+d  n  +  nLA+l++  G+ ++A+
  EEA21578.1 547 CYLTVAENDSANLQSRVNLAKLYETMGERDQAL 579
                 8************************99988886 PP

  == domain 7  score: -1.4 bits;  conditional E-value: 4.5
      TPR_17  16 ynnLAell 23 
                 y+++A++l
  EEA21578.1 947 YYYRAYAL 954
                 67777766 PP

  == domain 8  score: -0.6 bits;  conditional E-value: 2.6
      TPR_17   17 nnLAelllknGdlmtA 32  
                  +n++++++++G l +A
  EEA21578.1 1031 YNYGRVYHSLGLLHQA 1046
                  7899999888877766 PP

  == domain 9  score: -1.6 bits;  conditional E-value: 5.4
      TPR_17   21 elllknGdlmtArq 34  
                  ++++ nG+l+ Ar+
  EEA21578.1 1106 NIYALNGNLAGARE 1119
                  5899******9996 PP

>> TPR_MalT  MalT-like TPR region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0     0.056        50     147     184 ..     201     240 ..     189     259 .. 0.81
   2 ?    3.5   0.1     0.041        37     119     161 ..     322     364 ..     301     377 .. 0.85
   3 ?    4.9   0.1     0.015        14     150     202 ..     548     600 ..     459     634 .. 0.82
   4 ?   -1.8   0.0       1.7   1.5e+03     174     196 ..     769     791 ..     762     833 .. 0.66
   5 ?   -3.3   0.0       4.9   4.4e+03     124     148 ..     927     951 ..     921     972 .. 0.61
   6 ?    1.6   0.0      0.16   1.4e+02      44     116 ..    1031    1063 ..    1005    1068 .. 0.62

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.056
    TPR_MalT 147 eGielleql..epeaaldayvllarialaqGdleeAetll 184
                 ++iel++q    +    +a  ll +i la+G+ ++A t+l
  EEA21578.1 201 RAIELVQQAilVNPEMFAAHSLLSEIFLARGEKDKAVTAL 240
                 5677777755444555688999999999999999998876 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.041
    TPR_MalT 119 plvgfllvlladllyEwndLeeAeqhlqeGielleqlepeaal 161
                 p    +l+ la+ ++++ d ++A ++ ++Gie+  +l+++  +
  EEA21578.1 322 PHNIRALRHLAETYIDMQDVHKALEYYLAGIEYYMSLDNDENM 364
                 5555688999**********************99888776555 PP

  == domain 3  score: 4.9 bits;  conditional E-value: 0.015
    TPR_MalT 150 elleqlepeaaldayvllarialaqGdleeAetllekaeelaresnfhvdwla 202
                  l+   +  a l+++v la+++   G+ ++A+ ++++a  l re++ + ++++
  EEA21578.1 548 YLTVAENDSANLQSRVNLAKLYETMGERDQALYYVNQAVLLGREARGRSRRRR 600
                 444455778999**************************999999886554444 PP

  == domain 4  score: -1.8 bits;  conditional E-value: 1.7
    TPR_MalT 174 qGdleeAetllekaeelaresnf 196
                 qGd +eA+++l+ a+   +  ++
  EEA21578.1 769 QGDKDEAYDVLAAATDASVWYHY 791
                 78888888888877776555554 PP

  == domain 5  score: -3.3 bits;  conditional E-value: 4.9
    TPR_MalT 124 llvlladllyEwndLeeAeqhlqeG 148
                 llvl++++ly  n +  A ++  ++
  EEA21578.1 927 LLVLYGHILYSGNSFYPALNYYYRA 951
                 5566677777776666666655444 PP

  == domain 6  score: 1.6 bits;  conditional E-value: 0.16
    TPR_MalT   44 avlGeasllqGdleaAlqalqeaeklarqadslhvallallqqaeilvaqGrLheAletyeqalqlateqglq 116 
                  +++G+++                                           G Lh+A+  ye+ l+l  + + +
  EEA21578.1 1031 YNYGRVY----------------------------------------HSLGLLHQAIPCYERVLELGNQIQSP 1063
                  4444444........................................44556666666666666555544443 PP

>> Alkyl_sulf_dimr  Alkyl sulfatase dimerisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.4   0.0   0.00073      0.66      73     124 ..     187     238 ..     182     240 .. 0.91
   2 ?   -2.0   0.0       5.2   4.7e+03      95     120 ..     283     308 ..     264     313 .. 0.80
   3 ?    4.0   0.1     0.073        65      70     122 ..     526     578 ..     516     588 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00073
                      HHHHHHHHHTT-HHHHHHHHHHHHHHSTT-HHHHHHHHHHHHHHHHH-SSHH CS
  Alkyl_sulf_dimr  73 lekakealkegdyrwaaellnhlvfadpenaeakelkadaleqlgyqaesat 124
                       ++a+ea+ +gdy  a+el+++++  +pe  +a++l+ +++ ++g++ ++ t
       EEA21578.1 187 HSQATEAFIDGDYDRAIELVQQAILVNPEMFAAHSLLSEIFLARGEKDKAVT 238
                      57899***************************************99887665 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 5.2
                      HHHHSTT-HHHHHHHHHHHHHHHHH- CS
  Alkyl_sulf_dimr  95 lvfadpenaeakelkadaleqlgyqa 120
                      +++ d +  +a+  +a+a+++lgy  
       EEA21578.1 283 IIEIDGKSYNARFQRAAAYRELGYNG 308
                      55667778899999*********975 PP

  == domain 3  score: 4.0 bits;  conditional E-value: 0.073
                      HHHHHHHHHHHHTT-HHHHHHHHHHHHHHSTT-HHHHHHHHHHHHHHHHH-SS CS
  Alkyl_sulf_dimr  70 ekvlekakealkegdyrwaaellnhlvfadpenaeakelkadaleqlgyqaes 122
                      +  l++ + a+++ d+ +a +    + ++d+ n + +  +a+ +e +g++ ++
       EEA21578.1 526 SFFLAMGECAFACSDLSLAESCYLTVAENDSANLQSRVNLAKLYETMGERDQA 578
                      55688999999*************************************98765 PP

>> BTAD  Bacterial transcriptional activator domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0      0.49   4.4e+02       5      33 ..     182     210 ..     180     259 .. 0.89
   2 ?   14.3   0.6   4.5e-05      0.04      62     119 ..     291     348 ..     265     354 .. 0.90
   3 ?   -1.0   0.1       2.4   2.2e+03      98     122 ..     492     516 ..     490     520 .. 0.87

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.49
                 HHHHHHHHHHHHHHTT-HHHHHHHHHHHH CS
        BTAD   5 rfealvaagraalaagdpeeaaelleaAl 33 
                 +f+ l +++++a  +gd ++a+el+++A+
  EEA21578.1 182 EFKMLHSQATEAFIDGDYDRAIELVQQAI 210
                 688889999999999********999997 PP

  == domain 2  score: 14.3 bits;  conditional E-value: 4.5e-05
                 HHHHHHHHHHHHHTT-HHHHHHHHHHHHHHSTT-HHHHHHHHHHHHHTT-HHHHHHHH CS
        BTAD  62 lealealaeaelrlGraeealaelealvaehPlrErlhrqlmrAlarsGrqaeALevY 119
                   a  ++a+a  +lG   +a++e+e++++e P++ r+ r+l + +  + +  +ALe+Y
  EEA21578.1 291 YNARFQRAAAYRELGYNGRAAGEYERILKELPHNIRALRHLAETYIDMQDVHKALEYY 348
                 6788999**************************************************9 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 2.4
                 HHHHHHHHHHHTT-HHHHHHHHHHH CS
        BTAD  98 lhrqlmrAlarsGrqaeALevYerl 122
                 l+r+   Al   G   eAL+ Y+ l
  EEA21578.1 492 LYREAADALKDAGLFKEALRFYRPL 516
                 789999999999999*****99966 PP

>> TPR_20  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.0     0.034        31       8      47 ..     203     242 ..     198     250 .. 0.91
   2 ?    1.9   0.1      0.32   2.9e+02      11      46 ..     314     349 ..     291     362 .. 0.86
   3 ?    4.7   0.0     0.042        38      15      42 ..     552     579 ..     548     599 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.034
      TPR_20   8 laeleaalaanpddldarldlAlallaagryeeAleqLle 47 
                 ++ +++a+  np+  +a+  l++  la+g++++A+++L++
  EEA21578.1 203 IELVQQAILVNPEMFAAHSLLSEIFLARGEKDKAVTALFS 242
                 6778999999***************************985 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.32
      TPR_20  11 leaalaanpddldarldlAlallaagryeeAleqLl 46 
                  e+ l++ p ++ a   lA+ ++  +++ +Ale  l
  EEA21578.1 314 YERILKELPHNIRALRHLAETYIDMQDVHKALEYYL 349
                 5666888999*********************99665 PP

  == domain 3  score: 4.7 bits;  conditional E-value: 0.042
      TPR_20  15 laanpddldarldlAlallaagryeeAl 42 
                 ++++ ++l+ r++lA+++   g++++Al
  EEA21578.1 552 AENDSANLQSRVNLAKLYETMGERDQAL 579
                 678999********************98 PP

>> ChAPs  ChAPs (Chs5p-Arf1p-binding proteins)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.0   0.00068      0.61     234     293 ..     183     242 ..     175     264 .. 0.91
   2 ?   -0.8   0.0      0.68   6.1e+02     265     288 ..     322     345 ..     313     350 .. 0.85
   3 ?   -3.2   0.0       3.5   3.2e+03     268     294 ..     559     585 ..     527     601 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00068
                 HHHHHHHHHHHHHSS--HHHHHHHHHHHHH-TT-HHHHHHHHHHHHHTT-HHHHHHHHHT CS
       ChAPs 234 aelLllqaefllskkkeelAlevakravksaPsefktWalLvkvYikledienALltLNs 293
                  ++L+ qa       +++ A+e+ ++a+ + P  f+   lL++++++ ++ ++A+++L s
  EEA21578.1 183 FKMLHSQATEAFIDGDYDRAIELVQQAILVNPEMFAAHSLLSEIFLARGEKDKAVTALFS 242
                 67899999888889999**************************************99977 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.68
                 TT-HHHHHHHHHHHHHTT-HHHHH CS
       ChAPs 265 PsefktWalLvkvYikledienAL 288
                 P + +    L+++Yi+++d+++AL
  EEA21578.1 322 PHNIRALRHLAETYIDMQDVHKAL 345
                 677777789**************9 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 3.5
                 HHHHHHHHHHHHHTT-HHHHHHHHHT- CS
       ChAPs 268 fktWalLvkvYikledienALltLNsc 294
                  +  + L+k Y ++++ ++AL+ +N  
  EEA21578.1 559 LQSRVNLAKLYETMGERDQALYYVNQA 585
                 556678999999999999999999965 PP

>> TPR_6  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0       1.5   1.3e+03      10      27 ..     194     210 ..     185     215 .. 0.74
   2 ?    0.0   0.0       1.9   1.7e+03       7      23 ..     224     240 ..     219     241 .. 0.82
   3 ?    4.6   0.3     0.065        59       2      32 ..     293     323 ..     292     324 .. 0.87
   4 ?    3.0   0.2      0.22   1.9e+02       2      23 ..     327     348 ..     326     350 .. 0.89
   5 ?    2.2   0.1      0.39   3.5e+02       3      20 ..     562     579 ..     560     585 .. 0.87
   6 ?    6.2   0.0     0.021        19       2      28 ..    1029    1055 ..    1028    1056 .. 0.92

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 1.5
                 HHHHHHHHHHHHHHHHHH CS
       TPR_6  10 yrklgdtdkAlealerli 27 
                 ++  gd+d+A+e+ ++ i
  EEA21578.1 194 FID-GDYDRAIELVQQAI 210
                 444.5******9977776 PP

  == domain 2  score: 0.0 bits;  conditional E-value: 1.9
                 HHHHHHHHHHHHHHHHH CS
       TPR_6   7 alsyrklgdtdkAleal 23 
                  + +++ g++dkA++al
  EEA21578.1 224 SEIFLARGEKDKAVTAL 240
                 56778878******997 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.065
                 HHHHHHHHHHHHHHHH.HHHHHHHHHHHH-TT CS
       TPR_6   2 Alyklalsyrklgdtd.kAlealerlikeYPd 32 
                 A +++a +yr+l  +  +A   +er++ke P 
  EEA21578.1 293 ARFQRAAAYREL-GYNgRAAGEYERILKELPH 323
                 89**********.66669********999875 PP

  == domain 4  score: 3.0 bits;  conditional E-value: 0.22
                 HHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   2 AlyklalsyrklgdtdkAleal 23 
                 Al +la+ y+ ++d  kAle++
  EEA21578.1 327 ALRHLAETYIDMQDVHKALEYY 348
                 66689******88*******98 PP

  == domain 5  score: 2.2 bits;  conditional E-value: 0.39
                 HHHHHHHHHHHHHHHHHH CS
       TPR_6   3 lyklalsyrklgdtdkAl 20 
                   +la++y+ +g+ d+Al
  EEA21578.1 562 RVNLAKLYETMGERDQAL 579
                 679*******9******7 PP

  == domain 6  score: 6.2 bits;  conditional E-value: 0.021
                  HHHHHHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6    2 AlyklalsyrklgdtdkAlealerlik 28  
                  + y+ ++ y +lg   +A+  +er+++
  EEA21578.1 1029 VEYNYGRVYHSLGLLHQAIPCYERVLE 1055
                  679********99************96 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   3.8    0.0014       1.3     130     195 ..      84     153 ..      63     210 .. 0.52
   2 ?   -3.8   0.0       3.2   2.9e+03     441     490 ..    1068    1119 ..    1051    1122 .. 0.67

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0014
       CDC45 130 eesdeedeeeeeeddd...deeeeeeeeedeedeeedeeeskkkrksksdeeee...sddddersrkrrrse 195
                 ++++++  ++ ++dd+   +e++e  ++ +  +  + e+ +++ + + ++ee++    +d++ r+rkrrr+ 
  EEA21578.1  84 NDESDDV-DDYDDDDErlwNEGKEAYDDYSAIR-ADPEDPDSQASTEAESEEDDgydANDASPRPRKRRRRG 153
                 2222111.2222222212222222222222211.22222222222222222333455666667777777765 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 3.2
       CDC45  441 e...eeeeeeeeeeaeeeekeeeewvknFw.eAydaLdkknidlLkkglelaqs 490 
                  +   e++ ++ ++ ++++ek e+  v+ F  eA  aL+  ni +L+  l  a +
  EEA21578.1 1068 SvggEDKGKAVDHGEKKDEKPEDMLVEDFSpEAAVALQ--NIYALNGNLAGARE 1119
                  23446667777777888888899999999657888998..89998888877765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1127 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       570  (0.0317921); expected 358.6 (0.02)
Passed bias filter:                      437  (0.0243739); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                        23  (0.00128284); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              20  [number of targets reported over threshold]
# CPU time: 0.87u 0.34s 00:00:01.21 Elapsed: 00:00:00.53
# Mc/sec: 6347.27
//
Query:       EEA21579.1  [L=473]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.2e-22   79.0  48.9    2.6e-15   56.2  26.0    2.0  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.2  26.0   1.4e-19   2.6e-15       3     284 ..      86     366 ..      84     367 .. 0.79
   2 !   35.6  25.7   2.8e-13     5e-09      34     178 ..     328     471 ..     323     473 .] 0.91

  Alignments for each domain:
  == domain 1  score: 56.2 bits;  conditional E-value: 1.4e-19
       MFS_1   3 laaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgaga 101
                 +a+f s+  +++  +a+   l + +++s + i+l++    +g+a+a+++  ++   +G r v  l+  + +l+ ++ ++++++++l+v+ +++Glg g+
  EEA21579.1  86 FATFWSFVIMGANDAAY--GLETYYNLSYTIISLVFLSPVVGYAAAAILNNSIHMYLGQRGVAALSSSAHLLAYVVNSVHPPYPVLIVSFMFAGLGNGL 182
                 55555566666666666..46788*************************************************33333447788*************** PP

       MFS_1 102 lfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWrav...fyilaivsllafv.lfllll.....peepperkrkspkeeekgt 191
                 + +a +a+ia + +    +  +gll ++++lGa+l pl++  l++ + W++    +++++++++ +++ l +++      ++++++++++s++ +    
  EEA21579.1 183 ADSAWNAWIANLGNA---NELLGLLHGFYGLGAVLSPLIATSLVTKAEWPWFtfyYLMIGGAAIELGLtLPAFWAadkhdFRKRTAHSNSSDQHQ---- 274
                 ***********9987...999******************************98744444444444455677788877777777777777777777.... PP

       MFS_1 192 gpaplvpawkallkdpvlwillialllfffgfsg.lltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlllallll 284
                 +++ l++a+ +  + +v w l +a+ll+ +g+   l  ++ ++++ v++ + ++ +g++   +++++ ++++++g++  r+g ++++++ l+++
  EEA21579.1 275 KESRLKQALFSKSAARVTW-LCAAFLLGYVGTEVsLGGWVVTFMMRVRDGG-AFASGMTATGFWIGITVGRVVLGFVTPRIGEKIAIIVYLVAA 366
                 6666666444445555566.555555554444448****************.677776666677777777*************99999887765 PP

  == domain 2  score: 35.6 bits;  conditional E-value: 2.8e-13
       MFS_1  34 igllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfsl 132
                  g+ +t++ +g  v+ ++lG+++ r+G +  +++ l++  ++ l++++++++++ +v+ ++ G++ g lfpa++++++++ pk  + + ig+++a  ++
  EEA21579.1 328 SGMTATGFWIGITVGRVVLGFVTPRIGEKIAIIVYLVAAMAFELIFWLVPQFYVSAVAIAIEGFFLGPLFPAAVVAATKLLPKHLHVSSIGIAAALGGM 426
                 5888999***********************99999999999977777669999********************************************** PP

       MFS_1 133 GailgpllggllasslgWrav..fyilaivsllafvlfllllpeeppe 178
                 Ga++ p + g++a++ g +++  f +  ++++l+f+   lllp+ p++
  EEA21579.1 427 GAAIFPFAVGAIAQLKGVQVLqpFALGLLIAVLGFW---LLLPRMPKS 471
                 *****************8888779999999999988...888888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (473 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       730  (0.0407162); expected 358.6 (0.02)
Passed bias filter:                      352  (0.019633); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.24s 00:00:00.77 Elapsed: 00:00:00.40
# Mc/sec: 3581.95
//
Query:       EEA21580.1  [L=1000]
Description: calmodulin-binding protein Sha1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-06   27.9   0.1     0.0017   18.5   0.0    2.6  2  CH        Calponin homology (CH) domain
  ------ inclusion threshold ------
       0.29   11.0   3.4          1    9.3   3.4    2.0  1  IQ        IQ calmodulin-binding motif


Domain annotation for each model (and alignments):
>> CH  Calponin homology (CH) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.0   1.9e-07    0.0017      14     104 ..     638     761 ..     632     764 .. 0.77
   2 !    6.6   0.0   0.00099       8.8       4      45 ..     809     848 ..     806     871 .. 0.79

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 1.9e-07
                 HHTTSTTSSTTSCHHHHHTTSHHHHHHHHHH.................................STTTSSGGGSTTT...........HHHHHHHHHHH CS
          CH  14 hleeagpkvkvedfeedlrDGvlLckLlnkl.................................apglvdkkklnks...........efkkleNinla 68 
                 +l+++    ++++++ dlrDG+lL +L++ l                                                         +  k+ N++ a
  EEA21580.1 638 QLQDY--DFHIRNLAVDLRDGILLTRLVEILlypkpsqshtgkeisdtttfnddtsllgddtteW-----------PlsqklkvpcvsRAAKIFNVQIA 723
                 55554..55789**********************9988888888887777777777765555552...........033334555556*********** PP

                 HHHHHHHTTCHTT..SS-HHHHHTTSHHHHHHHHHHHH CS
          CH  69 ldvaekklgvpkv..lieaedlvegknksvltllaqLf 104
                 ld+++   g++ +  +i ae +v+g    +++ll+ L 
  EEA21580.1 724 LDALKGVTGIDAMvkDIHAEHIVDGYRENTMALLWVLV 761
                 ***998888877622469999**************885 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.00099
                 HHHHHHHHHHHHTTSTTSSTTSCHHHHHTTSHHHHHHHHHHS CS
          CH   4 kkellrWinshleeagpkvkvedfeedlrDGvlLckLlnkla 45 
                 ++ l++W     +   ++ + ++++++++DG ++  +++  +
  EEA21580.1 809 EDLLIKWASILAQL--KGLRLDNLTTSFADGRIFESIVEEYE 848
                 77899999887755..67778************998888774 PP

>> IQ  IQ calmodulin-binding motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   3.4   0.00011         1       2      13 ..     919     930 ..     918     933 .. 0.91

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00011
                 HHHHHHHHHHHH CS
          IQ   2 kaaikIQaawRG 13 
                 +aai+IQ+awR+
  EEA21580.1 919 RAAIVIQKAWRR 930
                 8**********7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1000 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       609  (0.0339673); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.75u 0.29s 00:00:01.04 Elapsed: 00:00:00.48
# Mc/sec: 6275.34
//
Query:       EEA21581.1  [L=621]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.7e-66  223.3   0.2    6.5e-66  222.5   0.0    1.5  2  Vezatin          Mysoin-binding motif of peroxisomes
     0.0026   17.7   1.2      0.005   16.7   1.2    1.5  1  PLDc_N           Phospholipase_D-nuclease N-terminal
  ------ inclusion threshold ------
      0.062   13.8   0.1       0.28   11.8   0.0    2.1  2  APC_u14          Unstructured region on APC between SAMP and 
       0.17   11.8   0.7       0.28   11.2   0.7    1.2  1  NMN_transporter  Nicotinamide mononucleotide transporter


Domain annotation for each model (and alignments):
>> Vezatin  Mysoin-binding motif of peroxisomes
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  222.5   0.0   1.5e-69   6.5e-66       3     277 ..     155     433 ..     153     435 .. 0.95
   2 ?   -3.1   0.1      0.91   4.1e+03     238     272 ..     574     606 ..     536     610 .. 0.65

  Alignments for each domain:
  == domain 1  score: 222.5 bits;  conditional E-value: 1.5e-69
     Vezatin   3 aliifLlkqqqlkksssslvkgfkllliisvklikv..lvlwrrqrlqvirqkalnqleefvknsqaldklvrkaLiliqEvelisrgyrlssplpPis 99 
                 ++i+ L+++++ ++ s+ ++  ++++l++++ l+++  ++++rrq+l+++rq+a+  +++f++  q++d+lv++++ +iqEvel+srgyr+s+plpP+s
  EEA21581.1 155 FSIVGLIHWSR-SRTSAGFNPRRIVILLVVLPLVGAvfYAFARRQWLRFVRQQAVQGASNFINGAQRFDSLVSSSVLFIQEVELVSRGYRISTPLPPVS 252
                 78999******.77888888888888888888888888************************************************************* PP

     Vezatin 100 rledqsqsrrcagLrkalystlsalflnlrkailkLlplsegdnlekYcdiynikelglseeslsdeeaeeetdeesLdaLkflfqkfnqlrkeflcqL 198
                 rle+  q rrc +Lr+a+++ ls ++ ++ +a + +  l++ +nlekY+diy+i++++l e+  s +  ++ +d++sL+ L++lf ++ + r   lc+L
  EEA21581.1 253 RLEETTQVRRCLRLRRAVSEGLSLVLDRYIQAQHTIGLLTDPSNLEKYYDIYEISMAELAEAR-SASLETTGEDQYSLKWLRILFSRLYTMRQSILCCL 350
                 **************************************************************7.666666777************************** PP

     Vezatin 199 LaLlsdsskenffrwklaheilsellqsLshvlaecleeLhrifeteese........ltperreraraklrkLnsLstlirsLqlh 277
                 LaL++++s +++  w+ a    +e +++L +v+ e+++++ +i+++++++        +++  r + ra+ r+LnsLs++ir L+++
  EEA21581.1 351 LALKAEGSGSDIPPWTCA----VEEMRNLAAVTHEAANKIANILNEKDKPtpplspipSASTGRDTLRAQARRLNSLSQGIRALHAK 433
                 ******************....9***********************************9999*********************9875 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 0.91
     Vezatin 238 LhrifeteeseltperreraraklrkLnsLstlir 272
                 + r+ e+  +  +   rera a  + L  L+t+i+
  EEA21581.1 574 IARVKEDRAR--QAAARERADASTNMLRELETVIK 606
                 3333333333..44457777777777777777775 PP

>> PLDc_N  Phospholipase_D-nuclease N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   1.2   1.1e-06     0.005       2      42 .]     155     197 ..     154     197 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 1.1e-06
      PLDc_N   2 lwiialidiirdrnpss....klaWllvilflPvlGailYllfGr 42 
                 ++i+ li++ r+r++++    +++ llv+  lP++Ga++Y +++r
  EEA21581.1 155 FSIVGLIHWSRSRTSAGfnprRIVILLVV--LPLVGAVFYAFARR 197
                 57899999999544444798555555555..8**********998 PP

>> APC_u14  Unstructured region on APC between SAMP and APC_crr
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       2.9   1.3e+04      71      94 .]      34      58 ..      31      58 .. 0.78
   2 ?   11.8   0.0   6.2e-05      0.28      12      55 ..     381     424 ..     373     449 .. 0.83

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 2.9
     APC_u14 71 lknasrdfndk.lpnneeRvrgsfa 94
                 +++s++f+ k +p    Rvr +fa
  EEA21581.1 34 GETHSQNFAPKgIPTIQTRVRDTFA 58
                5678888888767888999999997 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 6.2e-05
     APC_u14  12 ssassksqqdlekkkPtsPvkPmPqsseyraRlrknaesknnls 55 
                  +a++ ++  +ek kPt P  P+P +s  r  lr +a   n+ls
  EEA21581.1 381 EAANKIANILNEKDKPTPPLSPIPSASTGRDTLRAQARRLNSLS 424
                 56677777778***************999999988887776666 PP

>> NMN_transporter  Nicotinamide mononucleotide transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.7   6.2e-05      0.28      53     102 ..     150     197 ..     135     233 .. 0.63

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 6.2e-05
  NMN_transporter  53 lfyivmsiyGwirWsknkkkavrkltkkewlilllvivlgtallgfllka 102
                       +++ +si+G+i+Ws+++++    ++ + ++ill+v+ l+ a+++++ ++
       EEA21581.1 150 TIVTSFSIVGLIHWSRSRTS--AGFNPRRIVILLVVLPLVGAVFYAFARR 197
                      333449*********98754..4777777777777777777745544333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (621 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       902  (0.0503096); expected 358.6 (0.02)
Passed bias filter:                      598  (0.0333538); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.64u 0.29s 00:00:00.93 Elapsed: 00:00:00.44
# Mc/sec: 4211.69
//
Query:       EEA21582.1  [L=722]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     7e-151  503.5  23.8     7e-151  503.5  23.8    3.1  3  DUF2457   Protein of unknown function (DUF2457)


Domain annotation for each model (and alignments):
>> DUF2457  Protein of unknown function (DUF2457)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   5.9     0.088   1.6e+03     290     364 ..     100     173 ..      24     178 .. 0.71
   2 ?  -10.3  21.4         1   1.8e+04     278     354 ..     187     262 ..     143     274 .. 0.44
   3 !  503.5  23.8  3.9e-155    7e-151       1     468 []     276     722 .]     276     722 .] 0.83

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.088
     DUF2457 290 ekaspkrlrSppPrrrgksPpkkrlrsPpprklfdrks..prrlrspaptarkspaaspaeeaekvkfkelaerpgl 364
                 + +s   l+S       +sP+ + + sPp  +  +       r+ sp++  r+s  ++   +++ ++f+  a++p++
  EEA21582.1 100 SGHSTAELTSDGD---LTSPTYSNTSSPPHISTLQLAPvlEPRISSPPSDPRESKIEADLGRKRCISFACTAQQPQR 173
                 3333333333333...6889888888887744444333345699999999999999999999999****99999986 PP

  == domain 2  score: -10.3 bits;  conditional E-value: 1
     DUF2457 278 rdrr.kersrkksekaspkrlrSppPrrrgksPp..kkrlrsPpprklfdrksprrlrspaptarkspaaspaeeaekvk 354
                 +d +   +++ + +   p r     P + ++sPp   + +rsPpp   + r+ +  l+   +  ++ ++ +p++++ +++
  EEA21582.1 187 SDAAdPPQRKSRLTFVCPSRQSETRPTT-KRSPPytSRATRSPPP---TSRRPSAELKQVDAAPARVAEPAPVKKPGSIH 262
                 1111011111122233444444444422.3555332444566666...33333334444333333344444444444444 PP

  == domain 3  score: 503.5 bits;  conditional E-value: 3.9e-155
     DUF2457   1 RFheFasdeeeeddWirkdtevvkeklTinDtlkkEnairkLgeeaeeEaeeeeeeeeddeedeeddddddddedddedddeedededddstvedlsee 99 
                 RFheFas+ +e d W+ ++te+ + k+T+ D+++kE+airkLgeeae+Ea +eeee     e+e +++dd+dd+ + +d  ee      d+tv+d+s+ 
  EEA21582.1 276 RFHEFASSPDEVDGWMVQSTEH-QGKITLADCMEKEMAIRKLGEEAEAEAIAEEEE-----ENEMENEDDEDDTVNPDD--EE------DDTVHDFSS- 359
                 9*********************.*****************************8733.....333333333333333333..22......234566664. PP

     DUF2457 100 asdGyetDnEaGFAdSdeeddedddlelWtpkastaatsaekleqlatklerrlSveesSisslesakkseksrkkkarelkskkskirpetpeLPDST 198
                  +dG+e+DnEaGFAdSd+e+d d+++e+W+p+++taatsa++l++++ ++ rr+S  + Si+sl+++ ++  s++  +r+ ++  +  r++tp+LPDST
  EEA21582.1 360 -DDGNESDNEAGFADSDDESDGDSEYEFWAPSTTTAATSADNLDIVRLAADRRNS--NISIDSLKHEYSRPPSSMAGSRKSRRPINIPRAQTPDLPDST 455
                 .9*****************************************************..********97777666666666555545559*********** PP

     DUF2457 199 DFVCGTlDEDrplEeaYlsclearrrekhkviPQDiDPsFPtsdpededdddevakkkaeesddevwlhgeledldeelrdrrkersrkksekaspkrl 297
                 DFVCGTlDEDrplE+aY+sc+e+rrr+kh+++PQDiDPsFPt+dped+ddd  +++++ +++d +v++  ++e+  + lr+r+k + + k++++sp+r+
  EEA21582.1 456 DFVCGTLDEDRPLEAAYISCIEERRRKKHIPVPQDIDPSFPTTDPEDNDDD--IEENEDQDEDGDVAAAARIEE--DLLRGRSKGTLK-KTSRTSPRRV 549
                 *************************************************77..666666677878888888887..6789**976655.5699****** PP

     DUF2457 298 rSppPrrr.gksPpkkrlrsPpprklfdrksprrlrspaptarkspa.aspaeeaekvkfkelaerpgltrtkSlPrtpalffaqke.........akk 385
                 +Sp+Pr++ + sP  kr++sP+p          ++r +   a+  p+ a p+ + ++v++++ ++rp++trtkSlPrtp++ff+ +e         +  
  EEA21582.1 550 HSPAPRAHgHVSP--KRMKSPAP----------KARHA--LAAGLPTiAIPVPR-TGVNITGPVQRPHYTRTKSLPRTPNPFFKGLEesrlsgqhvSPG 633
                 ******9977899..******99..........22222..33344443445543.67****************************98666655544333 PP

     DUF2457 386 ekaeeeeskkkdthvRgaiDIvkGLEkkrqrRkekfyrkycrrarkeqlkerrpqpGkGaeRmrelGLlvagk.....v.dagnyvLSv 468
                 ++ +   s++++ h+Rg+iDI++GLE+krq+Rkekf+r++cr+a+ ++ +err+++GkGaeRm+elGL+va++     v ++++++LSv
  EEA21582.1 634 TSVDGPVSRSRELHTRGPIDIIQGLERKRQKRKEKFWRQHCRKAAAKEQSERRAARGKGAERMKELGLEVAERfkaygVgQDTQLMLSV 722
                 344788999**********************************7655556***********************8887745666899997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (722 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1045  (0.0582855); expected 358.6 (0.02)
Passed bias filter:                      413  (0.0230353); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.73u 0.33s 00:00:01.06 Elapsed: 00:00:00.46
# Mc/sec: 4670.64
//
Query:       EEA21583.1  [L=189]
Description: small monomeric GTPase SarA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.6e-64  216.6   0.0    1.8e-64  216.4   0.0    1.0  1  Arf        ADP-ribosylation factor family
    4.6e-10   39.2   0.0    1.9e-06   27.3   0.0    2.3  2  G-alpha    G-protein alpha subunit
    5.2e-08   32.5   0.0    6.4e-08   32.2   0.0    1.1  1  SRPRB      Signal recognition particle receptor beta subunit
    3.8e-07   30.3   0.0    1.2e-06   28.7   0.0    1.8  1  Roc        Ras of Complex, Roc, domain of DAPkinase
    4.8e-07   29.8   0.0    6.3e-07   29.5   0.0    1.2  1  MMR_HSR1   50S ribosome-binding GTPase
    7.3e-06   25.7   0.0    1.1e-05   25.1   0.0    1.3  1  Ras        Ras family
    0.00013   21.5   0.0    0.00014   21.3   0.0    1.1  1  Gtr1_RagA  Gtr1/RagA G protein conserved region
  ------ inclusion threshold ------
      0.081   12.4   0.0        2.3    7.7   0.0    2.0  1  GTP_EFTU   Elongation factor Tu GTP binding domain
       0.17   11.4   0.0        9.7    5.7   0.0    2.1  2  cobW       CobW/HypB/UreG, nucleotide-binding domain


Domain annotation for each model (and alignments):
>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  216.4   0.0   8.9e-68   1.8e-64       1     175 []       7     189 .]       7     189 .] 0.98

  Alignments for each domain:
  == domain 1  score: 216.4 bits;  conditional E-value: 8.9e-68
                 HHHHHHGGTT.TTEEEEEEEESTTSSHHHHHHHHHHSSCEECSSSSSEEEEEEEETTEEEEEEEE-SSGGGGGGGGGGCTTESEEEEEEETT-CTTHHH CS
         Arf   1 llsilaklklkkkelrilllGLDnaGKtTilkklkleelvttvPTigfnveeleiknlkftvwDvGGqeklRplWknYfektdavifvvDsadreRlee 99 
                 ++++la+l l +k++++l+lGLDnaGKtT+l++lk+++++  +PT ++++eel+i n +ft++D+GG++++R+lWk+Yf+++ +++f+vD+ d+eR+ e
  EEA21583.1   7 FYDVLASLGLLNKHAKLLFLGLDNAGKTTLLHMLKNDRVAILQPTAHPTSEELAIGNNRFTTFDLGGHQQARRLWKDYFPEVSGIVFLVDAKDHERFPE 105
                 57899********************************************************************************************** PP

                 HHHHHHHHCTSGCCTTSEEEEEEE-TTSTTSS-HHHHHHHTTGGG........SSSSSSEEEEEEBTTTTBTHHHHHHHHHHHH CS
         Arf 100 akeeLkalleeeelkevallvlaNKqDlpealseeelrellglee........lkgkrkleiqkcsavkgeglkeglewlsesi 175
                 +k+eL+all++eel++v++l+l+NK+D p+a+se+elr+++gl +        l+g r++e+++cs+v+++g+ eg++wls+++
  EEA21583.1 106 SKAELDALLAMEELSKVPFLILGNKIDHPDAVSEDELRHHMGLWQttgkgkvpLEGIRPIEVFMCSVVMRQGYGEGIRWLSQYV 189
                 *******************************************998888888888**************************985 PP

>> G-alpha  G-protein alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.5   0.0   0.00012      0.23      22      44 ..      19      41 ..      12      60 .. 0.83
   2 !   27.3   0.0   9.4e-10   1.9e-06     184     280 ..      47     132 ..      41     133 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00012
                .EEEEEEEESTTSSHHHHHHHHH CS
     G-alpha 22 revkllllGqseSGKsTilkqlk 44
                ++ kll+lG +  GK+T+l  lk
  EEA21583.1 19 KHAKLLFLGLDNAGKTTLLHMLK 41
                489****************9998 PP

  == domain 2  score: 27.3 bits;  conditional E-value: 9.4e-10
                 S-----SEEEEEEECT-TEEEEEEEE-SSHHHHHGTCCCTTTECEEEEEEEGGGTT-B-SS-TTSBHHHHHHHHHHCCCC-GGGTTSEEEEEEE-HH CS
     G-alpha 184 arlktvGisetkfevdsklefrivdvgGqrserkkWvpffddvdaiiFlvslsefdqvlyedekvnrleeslklFkeicnnkllkntpiiLflnKlD 280
                   ++t   +  ++ ++ +++f+ +d+gG+++ r+ W+ +f +v+ i+Flv  ++            r+ es +  ++++  ++l ++p++++ nK+D
  EEA21583.1  47 ILQPTAHPTSEELAIG-NNRFTTFDLGGHQQARRLWKDYFPEVSGIVFLVDAKD----------HERFPESKAELDALLAMEELSKVPFLILGNKID 132
                 5566777777888888.99******************************98333..........479999999999999999999999999999998 PP

>> SRPRB  Signal recognition particle receptor beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.2   0.0   3.2e-11   6.4e-08       3     131 ..      20     140 ..      18     147 .. 0.79

  Alignments for each domain:
  == domain 1  score: 32.2 bits;  conditional E-value: 3.2e-11
                 --EEEEE-STTSSHHHHHHHHHHSS---B---SS-EEETTG...GGTT-SEEEETT-GCCSHHHHHHHHHHGGEEEEEEEEETTS-HHHHHHHHHHHHH CS
       SRPRB   3 kpavllvGlsdsGKTslftrLttdsvkktvtSqessaalkvksekgskltliDfPGheklrqklleklkaksslkglvfvvDStidpkevkevAEllye 101
                 + ++l++Gl ++GKT+l++ L +d v   +   ++++ +      ++++t  D+ Gh++ r   +++     ++ g+vf+vD+   ++  ++ AEl   
  EEA21583.1  20 HAKLLFLGLDNAGKTTLLHMLKNDRVAILQPTAHPTSEELA--IGNNRFTTFDLGGHQQARRLWKDY---FPEVSGIVFLVDAKDHERFPESKAELDAL 113
                 6789********************99888777766554433..58899***********99765555...7899**********9999999****7444 PP

                 HHHHHHHHTT---EEEEEE-TTSTT---HH CS
       SRPRB 102 illiteklkdavdiliACnKqelflakspk 131
                 ++++      +v++li  nK +   a s+ 
  EEA21583.1 114 LAMEE---LSKVPFLILGNKIDHPDAVSED 140
                 43333...47899***99999877666655 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.7   0.0   6.2e-10   1.2e-06       1     119 [.      22     132 ..      22     133 .. 0.74

  Alignments for each domain:
  == domain 1  score: 28.7 bits;  conditional E-value: 6.2e-10
                 EEEEESSTTSSHHHHHHCHCT-CCC-EEETTTTEEEEEEECGGSGGCTTBTTTTCEEEEEEEE-SGGCTTTT-HHHHCTSCEEEEEEEGHHHHCH...H CS
         Roc   1 KvvlvGdsgvGKtsllkrfvedkfsekekstigvdfltkevtkikgvendkkvkkvklniWDtaGqerfrslhplylreaalailvydsrssenl...k 96 
                 K++++G  ++GKt+ll+ + +d++   + +t   +   +e+  i          + ++  +D++G+++ r l + y+ e + +++++d++++e++   k
  EEA21583.1  22 KLLFLGLDNAGKTTLLHMLKNDRVAILQ-PTAHPTS--EEL-AI---------GNNRFTTFDLGGHQQARRLWKDYFPEVSGIVFLVDAKDHERFpesK 107
                 89******************99996554.4433332..333.12.........223699****************************977665551115 PP

                 HHHHHHHHHCS..SS-EEEEEE-TT CS
         Roc  97 eWlkelkkvag..kspvilvgnkiD 119
                   l+ l ++ +  k p++++gnkiD
  EEA21583.1 108 AELDALLAMEElsKVPFLILGNKID 132
                 566666555442266899******9 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.5   0.0   3.1e-10   6.3e-07       2     113 ..      23     129 ..      22     130 .. 0.70

  Alignments for each domain:
  == domain 1  score: 29.5 bits;  conditional E-value: 3.1e-10
                 EEEEESTTSSHHHHHHHHHTSTEEESSSTTSSSSEEEEEEEETTEEEEEEECGGCSSHHHHHHHHHHHHHHHHCTSEEEEEEETT.TTCSHHHHHHHHH CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltgekaivsdkpgtTrdinegrvklkgkeielvDtpGliegaseekglgkaflaleeadlillvvdas.eeklkpldeelee 99 
                  +++G  N+GK+tL+  l ++++   ++ + T +++ +++++++++++  D+ G  +   + ++l k++    e++ i+++vda+ +e + + + el +
  EEA21583.1  23 LLFLGLDNAGKTTLLHMLKNDRV---AILQPTAHPTSEELAIGNNRFTTFDLGG-HQ---QARRLWKDYFP--EVSGIVFLVDAKdHERFPESKAELDA 112
                 5799***************9965...3456677888888888889*********.33...44467777775..789*******9863344444444444 PP

                 HHHH...TTSEEEEEEE CS
    MMR_HSR1 100 llee...akkplilvln 113
                 ll     +k p++++ n
  EEA21583.1 113 LLAMeelSKVPFLILGN 129
                 43222246666666655 PP

>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1   0.0   5.5e-09   1.1e-05       1     124 [.      22     139 ..      22     157 .. 0.86

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 5.5e-09
                 EEEEEESTTSSHHHHHHHHHHSSCSSSCTTTSSEEEEEEEEEETTEEEEEEEEEETTSGGGHHHHHHHHTTESEEEEEEETTBHHHHHTHHHHHHHHHH CS
         Ras   1 KlvlvGdsavGKtslllrfvkdkFkeeyesTigvdfytkeievdgkevkleiwDTAGqeefkslrelyyrdaegillvyditsresfenvkkwveeikr 99 
                 Kl+++G  + GKt+ll+   +d+     ++T     +++e+ + ++  +++ +D  G ++ ++l + y+ +++gi+ + d +++e f + k  ++ +  
  EEA21583.1  22 KLLFLGLDNAGKTTLLHMLKNDR-VAILQPTA--HPTSEELAIGNN--RFTTFDLGGHQQARRLWKDYFPEVSGIVFLVDAKDHERFPESKAELDALLA 115
                 899*************9876666.66789999..566677777666..5778***************************************99999999 PP

                 HST.TTSEEEEEEETTTGGGG-SS-H CS
         Ras 100 vae.envpivLvGnKvDleekravst 124
                 + e ++vp++++GnK+D  +  avs+
  EEA21583.1 116 MEElSKVPFLILGNKIDHPD--AVSE 139
                 999889***********876..4544 PP

>> Gtr1_RagA  Gtr1/RagA G protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.0   6.9e-08   0.00014       1     125 [.      22     135 ..      22     172 .. 0.79

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 6.9e-08
   Gtr1_RagA   1 kvLLmGksgsGKtsmrsiiFdnylardtlrlgatidveksevrflgnltlnlwDcgGqeafveeylssqkeeifrnvgvliyVfDvesre.leedletl 98 
                 k+L++G  ++GKt++  +    +    +  l+ t++ + +e+   gn  +  +D+gG ++          ++ f +v+ +++++D++++e ++e+ ++l
  EEA21583.1  22 KLLFLGLDNAGKTTLLHM----LKNDRVAILQPTAHPTSEEL-AIGNNRFTTFDLGGHQQARRL-----WKDYFPEVSGIVFLVDAKDHErFPESKAEL 110
                 89***********98654....56667788999***999999.79999*********9986554.....5789**************987677777777 PP

   Gtr1_RagA  99 keilealrqyspeakvfvlihKmDliq 125
                   +l a+ + s ++ + +l +K+D  +
  EEA21583.1 111 DALL-AMEELS-KVPFLILGNKIDHPD 135
                 6554.444444.466777778887654 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.0    0.0012       2.3      69     137 ..      63     136 ..      18     180 .. 0.67

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0012
                 SEEEEEEEESSSGGGHHHHHHHHHT-SEEEEEEETTTB.....STHHHHHHHHHHHHTTTEEEEEEESCGSTHH CS
    GTP_EFTU  69 kylinliDtPGHvdFskevirglrvlDgavlvvdaveG.....vepqteevlrlalkegvpiivfiNKmDrlka 137
                 + +++  D  GH++  +        + g v++vda++       ++    +l +    +vp+ ++ NK+D+++a
  EEA21583.1  63 NNRFTTFDLGGHQQARRLWKDYFPEVSGIVFLVDAKDHerfpeSKAELDALLAMEELSKVPFLILGNKIDHPDA 136
                 45566666666666666666666677788888888876666333333334444444456778888888888743 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.018        36      11      22 ..      31      42 ..      23      70 .. 0.78
   2 ?    5.7   0.0    0.0048       9.7     111     158 ..      87     139 ..      72     152 .. 0.73

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.018
                CCHHHHHHHHHC CS
        cobW 11 sGKTtLlnhlle 22
                +GKTtLl  l +
  EEA21583.1 31 AGKTTLLHMLKN 42
                9*****977653 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.0048
                 CECEEEEEEETTTH.....CCHCCHHHHHHHHHHTSS.EEEEE-HHHHCHC.. CS
        cobW 111 tldavvavvDaknl....eaeeekieekaedqlaaad.llvlnKtDlldeeal 158
                 +++++v++vDak      e++ e  + +a ++l +   l++ nK+D  d++ +
  EEA21583.1  87 EVSGIVFLVDAKDHerfpESKAELDALLAMEELSKVPfLILGNKIDHPDAVSE 139
                 6899*******9998888555666666666666665515566****9888733 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (189 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       357  (0.0199119); expected 358.6 (0.02)
Passed bias filter:                      352  (0.019633); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.44u 0.30s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1291.39
//
Query:       EEA21584.1  [L=187]
Description: small monomeric GTPase SarA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    5.4e-60  201.8   0.0    6.5e-60  201.5   0.0    1.0  1  Arf        ADP-ribosylation factor family
    4.4e-10   39.2   0.0    1.8e-06   27.4   0.0    2.3  2  G-alpha    G-protein alpha subunit
      5e-08   32.6   0.0    6.2e-08   32.3   0.0    1.1  1  SRPRB      Signal recognition particle receptor beta subunit
    3.6e-07   30.4   0.0    1.2e-06   28.7   0.0    1.8  1  Roc        Ras of Complex, Roc, domain of DAPkinase
    4.7e-07   29.9   0.0    6.1e-07   29.5   0.0    1.2  1  MMR_HSR1   50S ribosome-binding GTPase
    7.1e-06   25.7   0.0    1.1e-05   25.2   0.0    1.3  1  Ras        Ras family
    0.00012   21.5   0.0    0.00013   21.4   0.0    1.1  1  Gtr1_RagA  Gtr1/RagA G protein conserved region
  ------ inclusion threshold ------
      0.075   12.6   0.0        3.8    7.0   0.0    2.0  2  GTP_EFTU   Elongation factor Tu GTP binding domain
       0.17   11.5   0.0        9.5    5.8   0.0    2.1  2  cobW       CobW/HypB/UreG, nucleotide-binding domain


Domain annotation for each model (and alignments):
>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  201.5   0.0   3.3e-63   6.5e-60       1     166 [.       7     180 ..       7     185 .. 0.97

  Alignments for each domain:
  == domain 1  score: 201.5 bits;  conditional E-value: 3.3e-63
                 HHHHHHGGTT.TTEEEEEEEESTTSSHHHHHHHHHHSSCEECSSSSSEEEEEEEETTEEEEEEEE-SSGGGGGGGGGGCTTESEEEEEEETT-CTTHHH CS
         Arf   1 llsilaklklkkkelrilllGLDnaGKtTilkklkleelvttvPTigfnveeleiknlkftvwDvGGqeklRplWknYfektdavifvvDsadreRlee 99 
                 ++++la+l l +k++++l+lGLDnaGKtT+l++lk+++++  +PT ++++eel+i n +ft++D+GG++++R+lWk+Yf+++ +++f+vD+ d+eR+ e
  EEA21584.1   7 FYDVLASLGLLNKHAKLLFLGLDNAGKTTLLHMLKNDRVAILQPTAHPTSEELAIGNNRFTTFDLGGHQQARRLWKDYFPEVSGIVFLVDAKDHERFPE 105
                 57899********************************************************************************************** PP

                 HHHHHHHHCTSGCCTTSEEEEEEE-TTSTTSS-HHHHHHHTTGGG........SSSSSSEEEEEEBTTTTBTHHH CS
         Arf 100 akeeLkalleeeelkevallvlaNKqDlpealseeelrellglee........lkgkrkleiqkcsavkgeglke 166
                 +k+eL+all++eel++v++l+l+NK+D p+a+se+elr+++gl +        l+g r++e+++cs+v+++g + 
  EEA21584.1 106 SKAELDALLAMEELSKVPFLILGNKIDHPDAVSEDELRHHMGLWQttgkgkvpLEGIRPIEVFMCSVVMRQGTSP 180
                 *******************************************998888888888****************9875 PP

>> G-alpha  G-protein alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.6   0.0   0.00012      0.23      22      44 ..      19      41 ..      12      60 .. 0.83
   2 !   27.4   0.0   9.2e-10   1.8e-06     184     280 ..      47     132 ..      41     133 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00012
                .EEEEEEEESTTSSHHHHHHHHH CS
     G-alpha 22 revkllllGqseSGKsTilkqlk 44
                ++ kll+lG +  GK+T+l  lk
  EEA21584.1 19 KHAKLLFLGLDNAGKTTLLHMLK 41
                489****************9998 PP

  == domain 2  score: 27.4 bits;  conditional E-value: 9.2e-10
                 S-----SEEEEEEECT-TEEEEEEEE-SSHHHHHGTCCCTTTECEEEEEEEGGGTT-B-SS-TTSBHHHHHHHHHHCCCC-GGGTTSEEEEEEE-HH CS
     G-alpha 184 arlktvGisetkfevdsklefrivdvgGqrserkkWvpffddvdaiiFlvslsefdqvlyedekvnrleeslklFkeicnnkllkntpiiLflnKlD 280
                   ++t   +  ++ ++ +++f+ +d+gG+++ r+ W+ +f +v+ i+Flv  ++            r+ es +  ++++  ++l ++p++++ nK+D
  EEA21584.1  47 ILQPTAHPTSEELAIG-NNRFTTFDLGGHQQARRLWKDYFPEVSGIVFLVDAKD----------HERFPESKAELDALLAMEELSKVPFLILGNKID 132
                 5566777777888888.99******************************98333..........479999999999999999999999999999998 PP

>> SRPRB  Signal recognition particle receptor beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.3   0.0   3.1e-11   6.2e-08       3     131 ..      20     140 ..      18     147 .. 0.79

  Alignments for each domain:
  == domain 1  score: 32.3 bits;  conditional E-value: 3.1e-11
                 --EEEEE-STTSSHHHHHHHHHHSS---B---SS-EEETTG...GGTT-SEEEETT-GCCSHHHHHHHHHHGGEEEEEEEEETTS-HHHHHHHHHHHHH CS
       SRPRB   3 kpavllvGlsdsGKTslftrLttdsvkktvtSqessaalkvksekgskltliDfPGheklrqklleklkaksslkglvfvvDStidpkevkevAEllye 101
                 + ++l++Gl ++GKT+l++ L +d v   +   ++++ +      ++++t  D+ Gh++ r   +++     ++ g+vf+vD+   ++  ++ AEl   
  EEA21584.1  20 HAKLLFLGLDNAGKTTLLHMLKNDRVAILQPTAHPTSEELA--IGNNRFTTFDLGGHQQARRLWKDY---FPEVSGIVFLVDAKDHERFPESKAELDAL 113
                 6789********************99888777766554433..58899***********99765555...7899**********9999999****7444 PP

                 HHHHHHHHTT---EEEEEE-TTSTT---HH CS
       SRPRB 102 illiteklkdavdiliACnKqelflakspk 131
                 ++++      +v++li  nK +   a s+ 
  EEA21584.1 114 LAMEE---LSKVPFLILGNKIDHPDAVSED 140
                 43333...47899***99999877666655 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.7   0.0     6e-10   1.2e-06       1     119 [.      22     132 ..      22     133 .. 0.74

  Alignments for each domain:
  == domain 1  score: 28.7 bits;  conditional E-value: 6e-10
                 EEEEESSTTSSHHHHHHCHCT-CCC-EEETTTTEEEEEEECGGSGGCTTBTTTTCEEEEEEEE-SGGCTTTT-HHHHCTSCEEEEEEEGHHHHCH...H CS
         Roc   1 KvvlvGdsgvGKtsllkrfvedkfsekekstigvdfltkevtkikgvendkkvkkvklniWDtaGqerfrslhplylreaalailvydsrssenl...k 96 
                 K++++G  ++GKt+ll+ + +d++   + +t   +   +e+  i          + ++  +D++G+++ r l + y+ e + +++++d++++e++   k
  EEA21584.1  22 KLLFLGLDNAGKTTLLHMLKNDRVAILQ-PTAHPTS--EEL-AI---------GNNRFTTFDLGGHQQARRLWKDYFPEVSGIVFLVDAKDHERFpesK 107
                 89******************99996554.4433332..333.12.........223699****************************977665551115 PP

                 HHHHHHHHHCS..SS-EEEEEE-TT CS
         Roc  97 eWlkelkkvag..kspvilvgnkiD 119
                   l+ l ++ +  k p++++gnkiD
  EEA21584.1 108 AELDALLAMEElsKVPFLILGNKID 132
                 566666555442266899******9 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.5   0.0   3.1e-10   6.1e-07       2     113 ..      23     129 ..      22     130 .. 0.70

  Alignments for each domain:
  == domain 1  score: 29.5 bits;  conditional E-value: 3.1e-10
                 EEEEESTTSSHHHHHHHHHTSTEEESSSTTSSSSEEEEEEEETTEEEEEEECGGCSSHHHHHHHHHHHHHHHHCTSEEEEEEETT.TTCSHHHHHHHHH CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltgekaivsdkpgtTrdinegrvklkgkeielvDtpGliegaseekglgkaflaleeadlillvvdas.eeklkpldeelee 99 
                  +++G  N+GK+tL+  l ++++   ++ + T +++ +++++++++++  D+ G  +   + ++l k++    e++ i+++vda+ +e + + + el +
  EEA21584.1  23 LLFLGLDNAGKTTLLHMLKNDRV---AILQPTAHPTSEELAIGNNRFTTFDLGG-HQ---QARRLWKDYFP--EVSGIVFLVDAKdHERFPESKAELDA 112
                 5799***************9965...3456677888888888889*********.33...44467777775..789*******9863344444444444 PP

                 HHHH...TTSEEEEEEE CS
    MMR_HSR1 100 llee...akkplilvln 113
                 ll     +k p++++ n
  EEA21584.1 113 LLAMeelSKVPFLILGN 129
                 43222246666666655 PP

>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   0.0   5.3e-09   1.1e-05       1     124 [.      22     139 ..      22     157 .. 0.86

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 5.3e-09
                 EEEEEESTTSSHHHHHHHHHHSSCSSSCTTTSSEEEEEEEEEETTEEEEEEEEEETTSGGGHHHHHHHHTTESEEEEEEETTBHHHHHTHHHHHHHHHH CS
         Ras   1 KlvlvGdsavGKtslllrfvkdkFkeeyesTigvdfytkeievdgkevkleiwDTAGqeefkslrelyyrdaegillvyditsresfenvkkwveeikr 99 
                 Kl+++G  + GKt+ll+   +d+     ++T     +++e+ + ++  +++ +D  G ++ ++l + y+ +++gi+ + d +++e f + k  ++ +  
  EEA21584.1  22 KLLFLGLDNAGKTTLLHMLKNDR-VAILQPTA--HPTSEELAIGNN--RFTTFDLGGHQQARRLWKDYFPEVSGIVFLVDAKDHERFPESKAELDALLA 115
                 899*************9876666.66789999..566677777666..5778***************************************99999999 PP

                 HST.TTSEEEEEEETTTGGGG-SS-H CS
         Ras 100 vae.envpivLvGnKvDleekravst 124
                 + e ++vp++++GnK+D  +  avs+
  EEA21584.1 116 MEElSKVPFLILGNKIDHPD--AVSE 139
                 999889***********876..4544 PP

>> Gtr1_RagA  Gtr1/RagA G protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0   6.7e-08   0.00013       1     125 [.      22     135 ..      22     172 .. 0.79

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 6.7e-08
   Gtr1_RagA   1 kvLLmGksgsGKtsmrsiiFdnylardtlrlgatidveksevrflgnltlnlwDcgGqeafveeylssqkeeifrnvgvliyVfDvesre.leedletl 98 
                 k+L++G  ++GKt++  +    +    +  l+ t++ + +e+   gn  +  +D+gG ++          ++ f +v+ +++++D++++e ++e+ ++l
  EEA21584.1  22 KLLFLGLDNAGKTTLLHM----LKNDRVAILQPTAHPTSEEL-AIGNNRFTTFDLGGHQQARRL-----WKDYFPEVSGIVFLVDAKDHErFPESKAEL 110
                 89***********98654....56667788999***999999.79999*********9986554.....5789**************987677777777 PP

   Gtr1_RagA  99 keilealrqyspeakvfvlihKmDliq 125
                   +l a+ + s ++ + +l +K+D  +
  EEA21584.1 111 DALL-AMEELS-KVPFLILGNKIDHPD 135
                 6554.444444.466777778887654 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.1     0.017        33       2      30 ..      19      47 ..      18      62 .. 0.77
   2 ?    7.0   0.0    0.0019       3.8      70     139 ..      64     142 ..      51     179 .. 0.71

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.017
                CEEEEEEEESTTSSHHHHHHHHHHHTTSS CS
    GTP_EFTU  2 rirnigiighvDhGKtTLtdrLlyktgai 30
                ++ ++ ++g  ++GKtTL+  L  +  ai
  EEA21584.1 19 KHAKLLFLGLDNAGKTTLLHMLKNDRVAI 47
                567778888889******99887666555 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0019
                 EEEEEEEESSSGGGHHHHHHHHHT-SEEEEEEETTTB.....STHHHHHHHHHHHHTTTEEEEEEESCGST....HHHH CS
    GTP_EFTU  70 ylinliDtPGHvdFskevirglrvlDgavlvvdaveG.....vepqteevlrlalkegvpiivfiNKmDrl....kael 139
                  +++  D  GH++  +        + g v++vda++       ++    +l +    +vp+ ++ NK+D++    ++el
  EEA21584.1  64 NRFTTFDLGGHQQARRLWKDYFPEVSGIVFLVDAKDHerfpeSKAELDALLAMEELSKVPFLILGNKIDHPdavsEDEL 142
                 566777777777777777777788899999****9887773344444444555555688899999*****944443444 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.018        36      11      22 ..      31      42 ..      23      70 .. 0.78
   2 ?    5.8   0.0    0.0047       9.5     111     158 ..      87     139 ..      72     152 .. 0.73

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.018
                CCHHHHHHHHHC CS
        cobW 11 sGKTtLlnhlle 22
                +GKTtLl  l +
  EEA21584.1 31 AGKTTLLHMLKN 42
                9*****977653 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0047
                 CECEEEEEEETTTH.....CCHCCHHHHHHHHHHTSS.EEEEE-HHHHCHC.. CS
        cobW 111 tldavvavvDaknl....eaeeekieekaedqlaaad.llvlnKtDlldeeal 158
                 +++++v++vDak      e++ e  + +a ++l +   l++ nK+D  d++ +
  EEA21584.1  87 EVSGIVFLVDAKDHerfpESKAELDALLAMEELSKVPfLILGNKIDHPDAVSE 139
                 6899*******9998888555666666666666665515566****9888733 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (187 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       344  (0.0191868); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1210.04
//
Query:       EEA21585.1  [L=324]
Description: serine/threonine protein phosphatase PP1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.9e-40  138.5   0.1    5.2e-40  138.1   0.1    1.2  1  Metallophos  Calcineurin-like phosphoesterase
    1.1e-22   80.1   2.6    1.5e-22   79.8   1.7    1.7  2  STPPase_N    Serine-threonine protein phosphatase N-terminal 


Domain annotation for each model (and alignments):
>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.1   0.1   5.8e-44   5.2e-40       2     201 ..      57     248 ..      56     251 .. 0.94

  Alignments for each domain:
  == domain 1  score: 138.1 bits;  conditional E-value: 5.8e-44
                  EEEEEESBTBTTCCTHHHHHHHHHHHH..HHHTTESEEEEESTSSSSSHHHHHHHHH.HHHHHHHTSEEEEEC-TTS........CHHHHHHHHHHHH CS
  Metallophos   2 rilvigDlHlalgggqlddllkllddl..lreekpdlvllaGDlvdrgdlekellel.laalvkypipvylllGNHe........gfeeellnkygyl 88 
                  +i ++gD+H     gq++dll+l++    ++e  ++l+l  GD+vdrg  + e++ l la+++kyp ++++l+GNHe        gf++e++++y   
   EEA21585.1  57 PIKICGDIH-----GQYYDLLRLFEYGgfPPE-ANYLFL--GDYVDRGKQSLETICLlLAYKIKYPENFFILRGNHEcasinriyGFYDECKRRYN-- 144
                  6889*****.....**********77753555.99****..*******77777777779***********************************99.. PP

                  HHHHHHHEHHHCEEETSEEEEEETTEEEEEEEESE.CEEETHHHHHHHHHHHSCHHHHCC...HHHHHHHHHHTTCSEEEEEESSESSCSSSCSCCHH CS
  Metallophos  89 gifsepwrsdaevfnnlplaslgsgslkvlllhGg.spellvsldklgslnleleapepg...dewlkdlekrekadwvivlgHsplyrgsgylfgde 182
                      ++w++++++fn+lp+a++++   k++++hGg sp+l +s ++++++ +++++p+ g   d++++d       + + + g+s + rg + +fg++
   EEA21585.1 145 ---IKLWKTFTDCFNCLPIAAIIDE--KIFTMHGGlSPDL-NSMEQIRRVMRPTDIPDCGllcDLLWSD-------PDKDITGWSENDRGVSFTFGPD 229
                  ...99********************..********77777.****************************.......********************** PP

                  HHHHHHHHTTESEEEEESS CS
  Metallophos 183 aledllkkygvdlvisGHt 201
                  ++ ++l+k++ dl++++H+
   EEA21585.1 230 VVSRFLQKHDMDLICRAHQ 248
                  ******************8 PP

>> STPPase_N  Serine-threonine protein phosphatase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.8   1.7   1.7e-26   1.5e-22       1      48 []       8      55 ..       8      55 .. 0.97
   2 ?   -3.5   0.0       1.7   1.6e+04      22      32 ..     235     245 ..     234     246 .. 0.82

  Alignments for each domain:
  == domain 1  score: 79.8 bits;  conditional E-value: 1.7e-26
   STPPase_N  1 vDdiIerLlevrgkpggkkvqLseaEIrqlCakareiFLsQPtLLeLe 48
                +D+iI+rLlevrg+++gk+vqL e+EIr+lC+kareiF+sQP+LLeLe
  EEA21585.1  8 LDSIIDRLLEVRGSRPGKQVQLLESEIRHLCTKAREIFISQPILLELE 55
                7************8888******************************7 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 1.7
   STPPase_N  22 LseaEIrqlCa 32 
                 L+ +++ ++C+
  EEA21585.1 235 LQKHDMDLICR 245
                 77899999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (324 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       391  (0.0218082); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.46
# Mc/sec: 2138.35
//
Query:       EEA21586.1  [L=308]
Description: serine/threonine protein phosphatase PP1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.6e-40  138.7   0.1    4.5e-40  138.3   0.1    1.1  1  Metallophos  Calcineurin-like phosphoesterase
    1.1e-22   80.2   2.6    1.4e-22   79.9   1.7    1.7  2  STPPase_N    Serine-threonine protein phosphatase N-terminal 


Domain annotation for each model (and alignments):
>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.3   0.1     5e-44   4.5e-40       2     201 ..      57     248 ..      56     251 .. 0.94

  Alignments for each domain:
  == domain 1  score: 138.3 bits;  conditional E-value: 5e-44
                  EEEEEESBTBTTCCTHHHHHHHHHHHH..HHHTTESEEEEESTSSSSSHHHHHHHHH.HHHHHHHTSEEEEEC-TTS........CHHHHHHHHHHHH CS
  Metallophos   2 rilvigDlHlalgggqlddllkllddl..lreekpdlvllaGDlvdrgdlekellel.laalvkypipvylllGNHe........gfeeellnkygyl 88 
                  +i ++gD+H     gq++dll+l++    ++e  ++l+l  GD+vdrg  + e++ l la+++kyp ++++l+GNHe        gf++e++++y   
   EEA21586.1  57 PIKICGDIH-----GQYYDLLRLFEYGgfPPE-ANYLFL--GDYVDRGKQSLETICLlLAYKIKYPENFFILRGNHEcasinriyGFYDECKRRYN-- 144
                  6889*****.....**********77753555.99****..*******77777777779***********************************99.. PP

                  HHHHHHHEHHHCEEETSEEEEEETTEEEEEEEESE.CEEETHHHHHHHHHHHSCHHHHCC...HHHHHHHHHHTTCSEEEEEESSESSCSSSCSCCHH CS
  Metallophos  89 gifsepwrsdaevfnnlplaslgsgslkvlllhGg.spellvsldklgslnleleapepg...dewlkdlekrekadwvivlgHsplyrgsgylfgde 182
                      ++w++++++fn+lp+a++++   k++++hGg sp+l +s ++++++ +++++p+ g   d++++d       + + + g+s + rg + +fg++
   EEA21586.1 145 ---IKLWKTFTDCFNCLPIAAIIDE--KIFTMHGGlSPDL-NSMEQIRRVMRPTDIPDCGllcDLLWSD-------PDKDITGWSENDRGVSFTFGPD 229
                  ...99********************..********77777.****************************.......********************** PP

                  HHHHHHHHTTESEEEEESS CS
  Metallophos 183 aledllkkygvdlvisGHt 201
                  ++ ++l+k++ dl++++H+
   EEA21586.1 230 VVSRFLQKHDMDLICRAHQ 248
                  ******************8 PP

>> STPPase_N  Serine-threonine protein phosphatase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.9   1.7   1.5e-26   1.4e-22       1      48 []       8      55 ..       8      55 .. 0.97
   2 ?   -3.5   0.0       1.6   1.5e+04      22      32 ..     235     245 ..     234     246 .. 0.82

  Alignments for each domain:
  == domain 1  score: 79.9 bits;  conditional E-value: 1.5e-26
   STPPase_N  1 vDdiIerLlevrgkpggkkvqLseaEIrqlCakareiFLsQPtLLeLe 48
                +D+iI+rLlevrg+++gk+vqL e+EIr+lC+kareiF+sQP+LLeLe
  EEA21586.1  8 LDSIIDRLLEVRGSRPGKQVQLLESEIRHLCTKAREIFISQPILLELE 55
                7************8888******************************7 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 1.6
   STPPase_N  22 LseaEIrqlCa 32 
                 L+ +++ ++C+
  EEA21586.1 235 LQKHDMDLICR 245
                 77899999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (308 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2131.08
//
Query:       EEA21587.1  [L=307]
Description: serine/threonine protein phosphatase PP1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.5e-40  138.7   0.1    4.5e-40  138.3   0.1    1.1  1  Metallophos  Calcineurin-like phosphoesterase
    1.1e-22   80.2   2.6    1.4e-22   79.9   1.7    1.7  2  STPPase_N    Serine-threonine protein phosphatase N-terminal 


Domain annotation for each model (and alignments):
>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.3   0.1     5e-44   4.5e-40       2     201 ..      57     248 ..      56     251 .. 0.94

  Alignments for each domain:
  == domain 1  score: 138.3 bits;  conditional E-value: 5e-44
                  EEEEEESBTBTTCCTHHHHHHHHHHHH..HHHTTESEEEEESTSSSSSHHHHHHHHH.HHHHHHHTSEEEEEC-TTS........CHHHHHHHHHHHH CS
  Metallophos   2 rilvigDlHlalgggqlddllkllddl..lreekpdlvllaGDlvdrgdlekellel.laalvkypipvylllGNHe........gfeeellnkygyl 88 
                  +i ++gD+H     gq++dll+l++    ++e  ++l+l  GD+vdrg  + e++ l la+++kyp ++++l+GNHe        gf++e++++y   
   EEA21587.1  57 PIKICGDIH-----GQYYDLLRLFEYGgfPPE-ANYLFL--GDYVDRGKQSLETICLlLAYKIKYPENFFILRGNHEcasinriyGFYDECKRRYN-- 144
                  6889*****.....**********77753555.99****..*******77777777779***********************************99.. PP

                  HHHHHHHEHHHCEEETSEEEEEETTEEEEEEEESE.CEEETHHHHHHHHHHHSCHHHHCC...HHHHHHHHHHTTCSEEEEEESSESSCSSSCSCCHH CS
  Metallophos  89 gifsepwrsdaevfnnlplaslgsgslkvlllhGg.spellvsldklgslnleleapepg...dewlkdlekrekadwvivlgHsplyrgsgylfgde 182
                      ++w++++++fn+lp+a++++   k++++hGg sp+l +s ++++++ +++++p+ g   d++++d       + + + g+s + rg + +fg++
   EEA21587.1 145 ---IKLWKTFTDCFNCLPIAAIIDE--KIFTMHGGlSPDL-NSMEQIRRVMRPTDIPDCGllcDLLWSD-------PDKDITGWSENDRGVSFTFGPD 229
                  ...99********************..********77777.****************************.......********************** PP

                  HHHHHHHHTTESEEEEESS CS
  Metallophos 183 aledllkkygvdlvisGHt 201
                  ++ ++l+k++ dl++++H+
   EEA21587.1 230 VVSRFLQKHDMDLICRAHQ 248
                  ******************8 PP

>> STPPase_N  Serine-threonine protein phosphatase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.9   1.7   1.5e-26   1.4e-22       1      48 []       8      55 ..       8      55 .. 0.97
   2 ?   -3.5   0.0       1.6   1.5e+04      22      32 ..     235     245 ..     234     246 .. 0.82

  Alignments for each domain:
  == domain 1  score: 79.9 bits;  conditional E-value: 1.5e-26
   STPPase_N  1 vDdiIerLlevrgkpggkkvqLseaEIrqlCakareiFLsQPtLLeLe 48
                +D+iI+rLlevrg+++gk+vqL e+EIr+lC+kareiF+sQP+LLeLe
  EEA21587.1  8 LDSIIDRLLEVRGSRPGKQVQLLESEIRHLCTKAREIFISQPILLELE 55
                7************8888******************************7 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 1.6
   STPPase_N  22 LseaEIrqlCa 32 
                 L+ +++ ++C+
  EEA21587.1 235 LQKHDMDLICR 245
                 77899999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (307 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 2167.19
//
Query:       EEA21588.1  [L=814]
Description: Leucine Rich Repeat domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-13   49.7  18.8    1.3e-07   31.3   1.4    4.6  6  LRR_8     Leucine rich repeat
    5.9e-13   48.8  10.2     0.0011   19.3   0.3    4.6  4  LRR_4     Leucine Rich repeats (2 copies)
    5.2e-06   26.3  10.2        4.1    8.3   0.1    7.1  6  LRR_1     Leucine Rich Repeat
    8.1e-05   22.2   0.3     0.0053   16.3   0.6    2.4  2  LRR_9     Leucine-rich repeat
  ------ inclusion threshold ------
      0.064   13.3  17.3       0.94    9.7   0.5    6.0  6  LRR_6     Leucine Rich repeat


Domain annotation for each model (and alignments):
>> LRR_8  Leucine rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.0     0.014        51      15      32 ..     205     222 ..     204     224 .. 0.82
   2 ?   -3.8   0.1       3.2   1.1e+04       2      11 ..     236     245 ..     235     248 .. 0.48
   3 !   31.3   1.4   3.5e-11   1.3e-07       3      61 .]     408     466 ..     406     466 .. 0.95
   4 !   27.6   3.9   5.1e-10   1.8e-06       2      61 .]     432     490 ..     431     490 .. 0.98
   5 !   14.7   2.7   5.5e-06      0.02      20      61 .]     473     512 ..     465     512 .. 0.86
   6 !   17.4   0.4   7.5e-07    0.0027       3      60 ..     480     536 ..     478     537 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.014
                 EE-TTSSTT-TT--EEE- CS
       LRR_8  15 slddeaFkglsnLkvLdL 32 
                 +++ +aFk+ls+L+++d+
  EEA21588.1 205 AVPLHAFKNLSALEIIDI 222
                 677789999999999987 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 3.2
                 T-SEEE-TTS CS
       LRR_8   2 nLtsLdLsnN 11 
                 +L++L L + 
  EEA21588.1 236 QLRTLTLKRA 245
                 4555555444 PP

  == domain 3  score: 31.3 bits;  conditional E-value: 3.5e-11
                 -SEEE-TTS--SEE-TTSSTT.-TT--EEE--SS---GGGGGGGTT--S-.EEE--SS-- CS
       LRR_8   3 LtsLdLsnNrltslddeaFkg.lsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 
                 L+ L L +N+lt l+ ++F    + L +LdLs+Nl   + p+++ +L +Lr L+Ls++ +
  EEA21588.1 408 LRHLGLADNSLTTLPSDCFMPvANTLHSLDLSSNLFAEI-PDSLPSLVALRALNLSNCMI 466
                 899******************8888**************.9***************9865 PP

  == domain 4  score: 27.6 bits;  conditional E-value: 5.1e-10
                 T-SEEE-TTS--SEE-TTSSTT-TT--EEE--SS---GGGGGGGTT--S-.EEE--SS-- CS
       LRR_8   2 nLtsLdLsnNrltslddeaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 
                 +L+sLdLs+N + +++d+  + l +L+ L+Lsn  +++l+  a   Lp+++ L+L+gNrL
  EEA21588.1 432 TLHSLDLSSNLFAEIPDSLPS-LVALRALNLSNCMINSLRSIAKNPLPAITALNLRGNRL 490
                 69******************9.************************************98 PP

  == domain 5  score: 14.7 bits;  conditional E-value: 5.5e-06
                 SSTT-TT--EEE--SS---GGGGGGGTT--S-.EEE--SS-- CS
       LRR_8  20 aFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 
                 a + l++ + L+L+ N+l++l    ++ L sL+ LdL++N+L
  EEA21588.1 473 AKNPLPAITALNLRGNRLSSLA--GIERLLSLERLDLRDNNL 512
                 4455999**************5..****************98 PP

  == domain 6  score: 17.4 bits;  conditional E-value: 7.5e-07
                 -SEEE-TTS--SEE-TTSSTT-TT--EEE--SS---G.GGGGGGTT--S-.EEE--SS- CS
       LRR_8   3 LtsLdLsnNrltslddeaFkglsnLkvLdLsnNlltt.lspgafsgLpsLrsLdLsgNr 60 
                  t L+L+ Nrl+sl     ++l +L+ LdL++N+lt   +   + gLp +r++ +sgN+
  EEA21588.1 480 ITALNLRGNRLSSLAG--IERLLSLERLDLRDNNLTDpTEIARLTGLPEIREIWVSGNP 536
                 6889999999999986..68899999999999999997666789999999999999997 PP

>> LRR_4  Leucine Rich repeats (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.1      0.55     2e+03      21      32 ..     213     223 ..     204     254 .. 0.60
   2 !   13.1   0.6   2.8e-05       0.1       3      39 ..     408     446 ..     408     453 .. 0.79
   3 !   19.3   0.3   3.1e-07    0.0011       2      41 ..     455     495 ..     454     498 .. 0.86
   4 !   19.3   0.0   3.2e-07    0.0011       2      34 ..     501     536 ..     501     543 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.55
                 H-TT--EEE-.- CS
       LRR_4  21 klpnLkeLdLsg 32 
                 +l  L+ +d+ +
  EEA21588.1 213 NLSALEIIDI-D 223
                 4555666555.2 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 2.8e-05
                 --EEE--SS---E-S-....HHH-TT.--EEE-.-S-----G CS
       LRR_4   3 LevLdLsnNqltdipl....leklpn.LkeLdLsgNnlitdl 39 
                 L++L L++N lt++p+    +    n L++LdLs+N l   +
  EEA21588.1 408 LRHLGLADNSLTTLPSdcfmP--VANtLHSLDLSSN-LFAEI 446
                 9***************85333..4557******999.76666 PP

  == domain 3  score: 19.3 bits;  conditional E-value: 3.1e-07
                 S--EEE--SS---E-S-HH.H.-TT--EEE-.-S-----GGG CS
       LRR_4   2 nLevLdLsnNqltdiplle.k.lpnLkeLdLsgNnlitdlde 41 
                  L+ L+Lsn+++ ++ +++ + lp  + L+L gN ++++l +
  EEA21588.1 455 ALRALNLSNCMINSLRSIAkNpLPAITALNLRGN-RLSSLAG 495
                 599**************66688*********888.8877765 PP

  == domain 4  score: 19.3 bits;  conditional E-value: 3.2e-07
                 S--EEE--SS---E-S-...HHH-TT--EEE-.-S- CS
       LRR_4   2 nLevLdLsnNqltdipl...leklpnLkeLdLsgNn 34 
                 +Le LdL++N+ltd      l +lp  +e+++sgN+
  EEA21588.1 501 SLERLDLRDNNLTDPTEiarLTGLPEIREIWVSGNP 536
                 69************555766669************3 PP

>> LRR_1  Leucine Rich Repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.3   0.1    0.0011       4.1       2      20 ..     408     426 ..     407     428 .. 0.95
   2 ?    4.3   0.2     0.025        89       2      21 ..     433     451 ..     432     453 .. 0.77
   3 ?    4.6   0.1     0.019        69       2      13 ..     456     467 ..     455     475 .. 0.80
   4 ?    1.1   0.0      0.27   9.8e+02       4      14 ..     482     492 ..     479     499 .. 0.81
   5 !    6.4   0.1    0.0049        18       1      14 [.     501     514 ..     501     525 .. 0.84
   6 ?    0.3   0.0       0.5   1.8e+03       3      18 ..     528     543 ..     526     546 .. 0.86

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.0011
       LRR_1   2 LrhLdLsnnpllglppnsf 20 
                 LrhL L +n+l+ lp+++f
  EEA21588.1 408 LRHLGLADNSLTTLPSDCF 426
                 9*****************9 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.025
       LRR_1   2 LrhLdLsnnpllglppnsfq 21 
                 L +LdLs+n +   +p+s+ 
  EEA21588.1 433 LHSLDLSSNLF-AEIPDSLP 451
                 99*******99.56677665 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.019
       LRR_1   2 LrhLdLsnnpll 13 
                 Lr L+Lsn+ + 
  EEA21588.1 456 LRALNLSNCMIN 467
                 99*******873 PP

  == domain 4  score: 1.1 bits;  conditional E-value: 0.27
       LRR_1   4 hLdLsnnpllg 14 
                  L+L++n+l++
  EEA21588.1 482 ALNLRGNRLSS 492
                 69******954 PP

  == domain 5  score: 6.4 bits;  conditional E-value: 0.0049
       LRR_1   1 nLrhLdLsnnpllg 14 
                 +L++LdL++n+l++
  EEA21588.1 501 SLERLDLRDNNLTD 514
                 69*********954 PP

  == domain 6  score: 0.3 bits;  conditional E-value: 0.5
       LRR_1   3 rhLdLsnnpllglppn 18 
                 r++ +s+np++  +pn
  EEA21588.1 528 REIWVSGNPFTKTHPN 543
                 8899******988887 PP

>> LRR_9  Leucine-rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.6   1.5e-06    0.0053      45     116 ..     434     506 ..     429     508 .. 0.93
   2 !    5.7   0.0    0.0026       9.2      90     137 ..     502     550 ..     501     555 .. 0.87

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 1.5e-06
       LRR_9  45 dtidlsdndirkl.dgfPllkrlktlllnnnrivriaegleevlPnleelvltnnelqeladldPlaslkkle 116
                  ++dls n   ++ d++P l  l++l l+n  i  +    ++ lP +++l l +n+l +la ++ l sl++l+
  EEA21588.1 434 HSLDLSSNLFAEIpDSLPSLVALRALNLSNCMINSLRSIAKNPLPAITALNLRGNRLSSLAGIERLLSLERLD 506
                 5689999999988689*****************************************************9996 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.0026
       LRR_9  90 leelvltnnelqeladldPlaslkklellsllknpvtn.kkeyrlyviy 137
                 le l l +n+l++ +++  l+ l++++ + +  np t+ +++yr  + +
  EEA21588.1 502 LERLDLRDNNLTDPTEIARLTGLPEIREIWVSGNPFTKtHPNYRVTIFN 550
                 7889999****************************99725799988765 PP

>> LRR_6  Leucine Rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0      0.56     2e+03       5      17 ..     237     249 ..     234     250 .. 0.89
   2 ?    2.0   0.1     0.076   2.7e+02       4      16 ..     407     419 ..     406     420 .. 0.87
   3 ?    5.6   0.2    0.0056        20       3      13 ..     431     441 ..     429     444 .. 0.88
   4 ?    0.3   0.2      0.28     1e+03       5      14 ..     456     465 ..     456     468 .. 0.85
   5 ?    2.3   0.0     0.063   2.3e+02       5      16 ..     480     491 ..     478     493 .. 0.88
   6 ?    9.7   0.5   0.00026      0.94       4      17 ..     501     514 ..     499     515 .. 0.92

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.56
       LRR_6   5 LteLdLsgNdIgD 17 
                 L++L L+  +I+D
  EEA21588.1 237 LRTLTLKRANIND 249
                 9**********99 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.076
       LRR_6   4 hLteLdLsgNdIg 16 
                  L++L L++N ++
  EEA21588.1 407 FLRHLGLADNSLT 419
                 69********987 PP

  == domain 3  score: 5.6 bits;  conditional E-value: 0.0056
       LRR_6   3 thLteLdLsgN 13 
                 ++L +LdLs+N
  EEA21588.1 431 NTLHSLDLSSN 441
                 79********* PP

  == domain 4  score: 0.3 bits;  conditional E-value: 0.28
       LRR_6   5 LteLdLsgNd 14 
                 L++L+Ls + 
  EEA21588.1 456 LRALNLSNCM 465
                 89*****995 PP

  == domain 5  score: 2.3 bits;  conditional E-value: 0.063
       LRR_6   5 LteLdLsgNdIg 16 
                 +t+L+L+gN ++
  EEA21588.1 480 ITALNLRGNRLS 491
                 599******986 PP

  == domain 6  score: 9.7 bits;  conditional E-value: 0.00026
       LRR_6   4 hLteLdLsgNdIgD 17 
                 +L+ LdL++N+++D
  EEA21588.1 501 SLERLDLRDNNLTD 514
                 79***********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (814 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       640  (0.0356964); expected 358.6 (0.02)
Passed bias filter:                      355  (0.0198003); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.63u 0.26s 00:00:00.89 Elapsed: 00:00:00.42
# Mc/sec: 5840.63
//
Query:       EEA21589.1  [L=758]
Description: Patatin-like serine hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-48  164.5   7.0    1.6e-48  163.9   7.0    1.3  1  DUF3336         Domain of unknown function (DUF3336)
    3.5e-19   69.8   0.1      9e-18   65.2   0.0    2.4  2  Patatin         Patatin-like phospholipase
  ------ inclusion threshold ------
        0.1   12.7   1.1       0.17   11.9   1.1    1.4  1  TPR_MLP1_2      TPR/MLP1/MLP2-like protein
       0.13   12.6   0.1          1    9.8   0.0    2.4  2  GHMP_kinases_C  GHMP kinases C terminal


Domain annotation for each model (and alignments):
>> DUF3336  Domain of unknown function (DUF3336)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  163.9   7.0   3.6e-52   1.6e-48       1     137 [.     137     286 ..     137     287 .. 0.96

  Alignments for each domain:
  == domain 1  score: 163.9 bits;  conditional E-value: 3.6e-52
     DUF3336   1 lvawrgkrkklrkklrkattYeeWkeaAkeLDellgndeWkendes.yYdyklvkkvlkkLrklrek............edlkellellrtclkrNfag 86 
                 +v+w+g+r+klr+ l+++++Ye+W++aA++LD +lgn++Wkende+ yYdy +v+kv+k+Lr+lr++            e +++l +ll++c+k+Nf+g
  EEA21589.1 137 FVTWTGRREKLRRSLHSTRNYEDWQRAAHNLDIYLGNEKWKENDEYaYYDYLTVRKVVKQLRQLRKQveetqngnvqheEAVEDLRSLLEACVKNNFVG 235
                 689***************************************************************999999988888866888888************ PP

     DUF3336  87 ienprLYsetyiGTKklieeYidevekalellaetkqlsaeekleffketr 137
                 +enprLYse+y GTK+l++eYidev+ +le l++t++l++e k++ f++++
  EEA21589.1 236 VENPRLYSEAYSGTKHLVQEYIDEVHLCLEWLLNTRDLTKEVKYRHFRHLD 286
                 ***********************************************9986 PP

>> Patatin  Patatin-like phospholipase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.0     0.046   2.1e+02     104     179 ..      37     126 ..      11     149 .. 0.74
   2 !   65.2   0.0     2e-21     9e-18       1     202 [.     294     483 ..     294     485 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.046
     Patatin 104 kvladktlkrlsarlgklpllks.............lftanqavpaittataatastanranglytedddddvdladavraSs.afPglf 179
                 ++++d+ l+ + ++l+++  + +               +++++++++tt+++ +++ +++++g++   +++ + +   ++ +  ++ ++f
  EEA21589.1  37 PFITDDDLRAFEKALSAPEVEPLvaindwrpirqrvRRPFRSRAVSNTTNKPPRRTKDETREGFLYTLLKYPFLVTVFAWIAIlSIVYVF 126
                 5677777777777777775555588888888888888999999***********999999999999988888888777764433665555 PP

  == domain 2  score: 65.2 bits;  conditional E-value: 2e-21
     Patatin   1 LvlsGGGsrgafslgalkaLkkelgerfdiisGtSaGAiialllalgrdpaalvddlrnlllnkifdrdllirelaanlaarlsgllgkgglfdaealr 99 
                 L+lsGG + +++++g++kaL  + g  ++ii+GtS+GA++a+l+a+  ++++l++ l+ +l+++i+           + +a  ++++ +g+ fd+  ++
  EEA21589.1 294 LCLSGGATFAYYHFGVVKAL-LDNGVLPEIITGTSGGALVAALVATR-TDEELKQLLIPALAYRIKACH-------ERFPAWVKRWWKTGARFDTLDWA 383
                 9******************9.9*******************999986.888889999999999999999.......77778888888888888888888 PP

     Patatin 100 ellr.kvladktlkrlsarlgklpllkslftanqavpaittataatastanranglytedddddvdladavraSsafPglfppvsl.....dge..... 187
                 +  +  + +++t++++ +r g++                  ++    s+   +++l+++ + +d  +++av aS+a+Pg+++pv l     dg      
  EEA21589.1 384 RQCSwFTRGSMTFREAFERTGRI-----------------LNVSCVPSDPHSPTILANYLTSPDCVIWSAVIASAAVPGILNPVVLmkknkDGSlspys 465
                 77775446889999999999999.................78888999999999999999999******************888875554422266666 PP

     Patatin 188 ...lyvDGGilsNvPila 202
                    ++ DG+++  +P++a
  EEA21589.1 466 fghKWKDGSLRTDIPVKA 483
                 666779****99999987 PP

>> TPR_MLP1_2  TPR/MLP1/MLP2-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   1.1   3.9e-05      0.17      49      90 ..     187     228 ..     141     233 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 3.9e-05
  TPR_MLP1_2  49 lvkhaedvkelqalreelnelkaeiaelkaeaesakaelees 90 
                  +   + vk+l++lr++++e+++   + ++++e++++ le++
  EEA21589.1 187 YLTVRKVVKQLRQLRKQVEETQNGNVQHEEAVEDLRSLLEAC 228
                 55567889*****************************99986 PP

>> GHMP_kinases_C  GHMP kinases C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0      0.47   2.1e+03      10      46 ..     197     231 ..     190     236 .. 0.73
   2 ?    9.8   0.0   0.00023         1      39      71 ..     309     341 ..     308     350 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.47
  GHMP_kinases_C  10 lellgellnlsqrselkavvgilppeleellealsel 46 
                     l+ l++ + + q+     ++++  + l++llea+ ++
      EEA21589.1 197 LRQLRKQVEETQN--GNVQHEEAVEDLRSLLEACVKN 231
                     5667777777777..5668888899999999998665 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00023
  GHMP_kinases_C  39 llealselGalgaklsGaGgGptvfalfkdkde 71 
                     +++al+++G+l   ++G++gG+ v+al+ ++ +
      EEA21589.1 309 VVKALLDNGVLPEIITGTSGGALVAALVATRTD 341
                     57999***********************55544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (758 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       895  (0.0499191); expected 358.6 (0.02)
Passed bias filter:                      696  (0.0388198); expected 358.6 (0.02)
Passed Vit filter:                        79  (0.00440627); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.72u 0.27s 00:00:00.99 Elapsed: 00:00:00.43
# Mc/sec: 5292.62
//
Query:       EEA21590.1  [L=1166]
Description: ankyrin repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.9e-74  245.7   9.8      7e-14   52.2   0.1    7.1  6  Ank_2     Ankyrin repeats (3 copies)
    4.4e-68  224.8   9.0    3.9e-12   46.4   0.0    8.6  8  Ank_4     Ankyrin repeats (many copies)
    3.8e-52  172.6  21.4    1.8e-05   25.0   0.0   13.5 13  Ank       Ankyrin repeat
    4.6e-51  164.8  13.1    0.00018   21.7   0.0   13.7 13  Ank_3     Ankyrin repeat
    2.5e-49  164.7  23.9    2.4e-06   27.7   0.6   12.2 13  Ank_5     Ankyrin repeats (many copies)
  ------ inclusion threshold ------
       0.09   13.0   0.1       0.29   11.4   0.1    1.9  1  DUF1612   Protein of unknown function (DUF1612)


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.5   0.4   1.4e-15   4.1e-12       3      81 ..     405     494 ..     403     497 .. 0.87
   2 !   40.7   0.1   9.3e-14   2.8e-10      27      83 .]     500     562 ..     493     562 .. 0.89
   3 !   34.1   0.1     1e-11   3.1e-08      27      78 ..     566     623 ..     563     628 .. 0.84
   4 !   52.2   0.1   2.4e-17     7e-14      13      76 ..     614     688 ..     613     694 .. 0.85
   5 !   36.5   0.0   1.8e-12   5.3e-09      25      83 .]     697     762 ..     689     762 .. 0.81
   6 !   38.8   0.0   3.5e-13     1e-09       1      74 [.     769     855 ..     769     862 .. 0.85

  Alignments for each domain:
  == domain 1  score: 46.5 bits;  conditional E-value: 1.4e-15
       Ank_2   3 lAakngnlelvklLl.egadpn..k..ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinl 81 
                  Aa++g+ + v+ L+ +g+d++  +  + ++aL++Aa+ g+ +i+ lL+++      +d +g t+Lh+Aa+ gh  +v+lL+   +di++
  EEA21590.1 405 KAAQFGARYDVERLIgSGHDIEelHfhTRRNALMVAAHCGKDDIADLLIQNnaqlnrTDASGSTALHLAASRGHVSVVELLVMEAIDIEA 494
                 6999998899*****99999987636699***********99*******966776666699*********99**********77788875 PP

  == domain 2  score: 40.7 bits;  conditional E-value: 9.3e-14
       Ank_2  27 ktaLhyAakngnleivklLleh...ad...ndgrtpLhyAarsghleivklLlekgadinlkd 83 
                 +taL+++a ng+l++ ++Lle+   ++   ++ +t+Lh+Aar+g  ei+ lL+ +gadi+++d
  EEA21590.1 500 RTALWVSANNGHLQTTQMLLENgakVNaraDNQMTALHVAARQGDVEIAGLLVSYGADIDARD 562
                 8*******************98877445578899*******************99****9987 PP

  == domain 3  score: 34.1 bits;  conditional E-value: 1e-11
       Ank_2  27 ktaLhyAakngnleivklLleh...ad...ndgrtpLhyAarsghleivklLlekgad 78 
                 +taLhyA+++g +++v lLl +   +d   ++ rtpL++Aa  g+l +v+lL++++++
  EEA21590.1 566 MTALHYACEGGFVNVVDLLLRNkanIDvagSERRTPLICAAATGQLLAVQLLMNRKSK 623
                 69******************9775633666999********99*********966554 PP

  == domain 4  score: 52.2 bits;  conditional E-value: 2.4e-17
       Ank_2  13 vklLl.egadpn..k.ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlekg 76 
                 v+lL+  +++++  +  g+taLh+Aa ng++eiv +L +h       ++ +grtpLh+Aa ++++ +v++L+ k 
  EEA21590.1 614 VQLLMnRKSKFKtvDeGGMTALHWAAYNGHVEIVDYLTSHsrgllasTNVQGRTPLHLAAMNSQFAVVEFLIRKS 688
                 788886555555553589*********************999999877799*********************654 PP

  == domain 5  score: 36.5 bits;  conditional E-value: 1.8e-12
       Ank_2  25 ngktaLhyAakngnleivklLleh.ad......ndgrtpLhyAarsghleivklLlekgadinlkd 83 
                  g++aLhyA+k++n+eiv+lLl   a+         + p+h++a +g+  +v+lL+ekga+++++d
  EEA21590.1 697 AGLNALHYACKADNTEIVRLLLTSgANiegetgFRQQRPIHMSAAEGSVGLVRLLCEKGASLEVRD 762
                 479*******************8674433434433567**999999***************99887 PP

  == domain 6  score: 38.8 bits;  conditional E-value: 3.5e-13
       Ank_2   1 LhlAakngnlelvklLl.egadpn.....k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLle 74 
                 L +Aa+ng+  +v+ Ll +g+ ++        + ++L +Aak+g+  +v+lL++h       d+ g+tp  yAa +gh+++++l + 
  EEA21590.1 769 LCVAARNGHVAAVQTLLdFGSPLHlrfgvRsHEDSPLCLAAKGGYFPVVSLLIKHgasvlsKDEMGWTPARYAAYYGHPDVLELIVA 855
                 6789****99*******98877666454415789********************99888766699*****************99883 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.8   0.2   3.1e-13   9.3e-10       2      55 .]     434     486 ..     433     486 .. 0.95
   2 !   32.8   0.1   2.4e-11   7.2e-08       2      55 .]     500     552 ..     499     552 .. 0.92
   3 !   46.4   0.0   1.3e-15   3.9e-12       2      55 .]     533     585 ..     532     585 .. 0.98
   4 !   34.9   0.0   5.5e-12   1.7e-08       1      54 [.     598     650 ..     598     651 .. 0.96
   5 !   19.2   0.0   4.6e-07    0.0014      31      55 .]     661     685 ..     655     685 .. 0.91
   6 !   15.0   0.0   9.6e-06     0.029       2      26 ..     699     723 ..     692     729 .. 0.70
   7 !   27.0   0.0   1.6e-09   4.8e-06       4      55 .]     735     785 ..     733     785 .. 0.97
   8 !   27.6   0.0     1e-09     3e-06       2      53 ..     802     852 ..     801     854 .. 0.94

  Alignments for each domain:
  == domain 1  score: 38.8 bits;  conditional E-value: 3.1e-13
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 + aL  aa+ g+ ++++lL++++a++n++ ++sG talh Aa+rg+v++++lL+
  EEA21590.1 434 RNALMVAAHCGKDDIADLLIQNNAQLNRT-DASGSTALHLAASRGHVSVVELLV 486
                 6789999999*******************.**********************96 PP

  == domain 2  score: 32.8 bits;  conditional E-value: 2.4e-11
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +taL   a+ g+l++ + Lle+ga +na+  ++++talh Aa+ g+vei+ lL+
  EEA21590.1 500 RTALWVSANNGHLQTTQMLLENGAKVNAR-ADNQMTALHVAARQGDVEIAGLLV 552
                 789988999********************.666****************99885 PP

  == domain 3  score: 46.4 bits;  conditional E-value: 1.3e-15
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +taLh aa +g++e++ lL+++gadi+a+ ++s +talh+A+ +g+v+++ lLl
  EEA21590.1 533 MTALHVAARQGDVEIAGLLVSYGADIDAR-DASMMTALHYACEGGFVNVVDLLL 585
                 8****************************.**********************97 PP

  == domain 4  score: 34.9 bits;  conditional E-value: 5.5e-12
       Ank_4   1 eltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54 
                 ++t+L  aa+ g+l +v+lL +++     + ++ G+talh Aa++g+vei+ +L
  EEA21590.1 598 RRTPLICAAATGQLLAVQLLMNRKSKFKTV-DEGGMTALHWAAYNGHVEIVDYL 650
                 589******************999999999.*********************99 PP

  == domain 5  score: 19.2 bits;  conditional E-value: 4.6e-07
       Ank_4  31 dnrsGetalhiAakrgnveilklLl 55 
                 +n +G+t+lh Aa+++++ ++++L+
  EEA21590.1 661 TNVQGRTPLHLAAMNSQFAVVEFLI 685
                 4899********************8 PP

  == domain 6  score: 15.0 bits;  conditional E-value: 9.6e-06
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgad 26 
                 l aLhya+++ ++e+vrlLl +ga+
  EEA21590.1 699 LNALHYACKADNTEIVRLLLTSGAN 723
                 4567777777777777777766665 PP

  == domain 7  score: 27.0 bits;  conditional E-value: 1.6e-09
       Ank_4   4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++h+ a++g + lvrlL ekga++  + +++G+ al  Aa++g+v +++ Ll
  EEA21590.1 735 PIHMSAAEGSVGLVRLLCEKGASLEVR-DAEGDRALCVAARNGHVAAVQTLL 785
                 79999**********************.*********************997 PP

  == domain 8  score: 27.6 bits;  conditional E-value: 1e-09
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilkl 53 
                  ++L  aa+ g +++v lL+ +ga++    ++ G+t+  +Aa+ g++++l+l
  EEA21590.1 802 DSPLCLAAKGGYFPVVSLLIKHGASVLSK-DEMGWTPARYAAYYGHPDVLEL 852
                 589999**********************9.********************97 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.4   0.00015      0.46       5      31 ..     436     463 ..     434     464 .. 0.90
   2 !   19.2   0.0   4.1e-07    0.0012       2      27 ..     466     492 ..     465     497 .. 0.81
   3 !   13.2   0.0   3.1e-05     0.093       3      30 ..     500     528 ..     499     530 .. 0.94
   4 !   25.0   0.0   6.1e-09   1.8e-05       3      31 ..     533     562 ..     531     563 .. 0.93
   5 !   18.9   0.0     5e-07    0.0015       3      28 ..     566     592 ..     565     595 .. 0.86
   6 ?    1.1   0.0      0.21   6.3e+02       3      22 ..     599     618 ..     598     622 .. 0.83
   7 !   19.5   0.1   3.2e-07   0.00095       2      28 ..     631     662 ..     630     665 .. 0.81
   8 !   17.4   0.0   1.4e-06    0.0043       2      26 ..     665     689 ..     664     695 .. 0.80
   9 !   21.4   0.1   7.8e-08   0.00023       2      27 ..     698     724 ..     697     725 .. 0.92
  10 ?    3.6   0.0     0.036   1.1e+02       5      31 ..     735     762 ..     735     763 .. 0.77
  11 ?    2.6   0.0     0.069   2.1e+02       4      25 ..     767     789 ..     764     794 .. 0.78
  12 !   13.3   0.0   2.9e-05     0.086       3      31 ..     802     831 ..     800     832 .. 0.88
  13 !    6.9   0.0     0.003         9       1      30 [.     833     861 ..     833     863 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00015
                 HHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   5 PLHlAatngkkriiklLL.hGAnlnald 31 
                 +L++Aa++gk +i+ lL+ + A ln +d
  EEA21590.1 436 ALMVAAHCGKDDIADLLIqNNAQLNRTD 463
                 9*****************66799*9988 PP

  == domain 2  score: 19.2 bits;  conditional E-value: 4.1e-07
                 SBBHHHHHHHHTTHHHHHHHH.TTTST CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnl 27 
                 G T+LHlAa++g++++++lL+    ++
  EEA21590.1 466 GSTALHLAASRGHVSVVELLVmEAIDI 492
                 89*****************98444455 PP

  == domain 3  score: 13.2 bits;  conditional E-value: 3.1e-05
                 BBHHHHHHHHTTHHHHHHHH.TTTSTTCB CS
         Ank   3 nTPLHlAatngkkriiklLL.hGAnlnal 30 
                 +T+L + a+ng+++ +++LL +GA +na+
  EEA21590.1 500 RTALWVSANNGHLQTTQMLLeNGAKVNAR 528
                 59****9*************99*****97 PP

  == domain 4  score: 25.0 bits;  conditional E-value: 6.1e-09
                 BBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   3 nTPLHlAatngkkriiklLL.hGAnlnald 31 
                 +T+LH+Aa+ g+++i+ lL+ +GA+++a+d
  EEA21590.1 533 MTALHVAARQGDVEIAGLLVsYGADIDARD 562
                 8*******************88*******9 PP

  == domain 5  score: 18.9 bits;  conditional E-value: 5e-07
                 BBHHHHHHHHTTHHHHHHHH.TTTSTT CS
         Ank   3 nTPLHlAatngkkriiklLL.hGAnln 28 
                 +T+LH+A+ +g ++++ lLL + An++
  EEA21590.1 566 MTALHYACEGGFVNVVDLLLrNKANID 592
                 7*******7777********6669997 PP

  == domain 6  score: 1.1 bits;  conditional E-value: 0.21
                 BBHHHHHHHHTTHHHHHHHH CS
         Ank   3 nTPLHlAatngkkriiklLL 22 
                 +TPL +Aa  g++  ++lL 
  EEA21590.1 599 RTPLICAAATGQLLAVQLLM 618
                 6****999779999999875 PP

  == domain 7  score: 19.5 bits;  conditional E-value: 3.2e-07
                 SBBHHHHHHHHTTHHHHHHHH.T..T..TSTT CS
         Ank   2 GnTPLHlAatngkkriiklLL.h..G..Anln 28 
                 G+T+LH+Aa+ng+++i+ +L  h  G  A+ n
  EEA21590.1 631 GMTALHWAAYNGHVEIVDYLTsHsrGllASTN 662
                 9******************9876434666666 PP

  == domain 8  score: 17.4 bits;  conditional E-value: 1.4e-06
                 SBBHHHHHHHHTTHHHHHHHH.TTTS CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAn 26 
                 G+TPLHlAa+n +  ++++L+ ++ +
  EEA21590.1 665 GRTPLHLAAMNSQFAVVEFLIrKS-C 689
                 9********888899*****9545.4 PP

  == domain 9  score: 21.4 bits;  conditional E-value: 7.8e-08
                 SBBHHHHHHHHTTHHHHHHHH.TTTST CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnl 27 
                 G  +LH+A+  ++++i++lLL +GAn+
  EEA21590.1 698 GLNALHYACKADNTEIVRLLLtSGANI 724
                 6679*****************99**97 PP

  == domain 10  score: 3.6 bits;  conditional E-value: 0.036
                 HHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   5 PLHlAatngkkriiklLL.hGAnlnald 31 
                 P H+ a +g++  ++lL  +GA+l  +d
  EEA21590.1 735 PIHMSAAEGSVGLVRLLCeKGASLEVRD 762
                 67854547877799988888***99887 PP

  == domain 11  score: 2.6 bits;  conditional E-value: 0.069
                 BHHHHHHHHTTHHHHHHHH.TTT CS
         Ank   4 TPLHlAatngkkriiklLL.hGA 25 
                  +L +Aa+ng++  ++ LL  G+
  EEA21590.1 767 RALCVAARNGHVAAVQTLLdFGS 789
                 58889*************95585 PP

  == domain 12  score: 13.3 bits;  conditional E-value: 2.9e-05
                 BBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   3 nTPLHlAatngkkriiklLL.hGAnlnald 31 
                 ++PL lAa +g   +++lL+ hGA++ ++d
  EEA21590.1 802 DSPLCLAAKGGYFPVVSLLIkHGASVLSKD 831
                 79******888888***********98887 PP

  == domain 13  score: 6.9 bits;  conditional E-value: 0.003
                 TSBBHHHHHHHHTTHHHHHHHHTTTSTTCB CS
         Ank   1 dGnTPLHlAatngkkriiklLLhGAnlnal 30 
                 +G+TP  +Aa++g++++++l++  A++ a+
  EEA21590.1 833 MGWTPARYAAYYGHPDVLELIV-AAEPSAV 861
                 6999999************998.8888876 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.1   5.6e-05      0.17       3      30 ..     434     460 ..     432     461 .. 0.90
   2 !   16.0   0.0   4.1e-06     0.012       2      30 ..     466     493 ..     465     494 .. 0.91
   3 !    9.2   0.0   0.00069         2       3      31 .]     500     527 ..     498     527 .. 0.94
   4 !   19.2   0.0   3.9e-07    0.0012       1      31 []     531     560 ..     531     560 .. 0.95
   5 !   17.8   0.1   1.1e-06    0.0033       3      30 ..     566     592 ..     565     593 .. 0.93
   6 ?    2.2   0.0      0.13   3.9e+02       3      23 ..     599     619 ..     597     624 .. 0.86
   7 !   17.7   0.0   1.2e-06    0.0036       2      23 ..     631     652 ..     630     656 .. 0.92
   8 !   21.7   0.0   6.1e-08   0.00018       2      29 ..     665     691 ..     664     693 .. 0.90
   9 !   18.6   0.1   6.2e-07    0.0019       2      29 ..     698     724 ..     697     726 .. 0.92
  10 ?    4.0   0.0     0.034     1e+02       3      29 ..     733     758 ..     731     760 .. 0.89
  11 !    5.7   0.0    0.0093        28       5      29 ..     768     791 ..     764     793 .. 0.83
  12 ?    5.5   0.0     0.011        34       4      29 ..     803     827 ..     800     829 .. 0.89
  13 !    8.0   0.0    0.0018       5.2       2      23 ..     834     855 ..     833     860 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 5.6e-05
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvn 30 
                 +++L++Aa++g+ +i+++L++ ++a +n
  EEA21590.1 434 RNALMVAAHCGKDDIADLLIQ-NNAQLN 460
                 789******************.788776 PP

  == domain 2  score: 16.0 bits;  conditional E-value: 4.1e-06
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G t+LhlAa+ g++++v++L+    +d+ 
  EEA21590.1 466 GSTALHLAASRGHVSVVELLVM-EAIDIE 493
                 89*******************9.788875 PP

  == domain 3  score: 9.2 bits;  conditional E-value: 0.00069
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvna 31 
                 +t+L + a +g+l   ++Lle +ga vna
  EEA21590.1 500 RTALWVSANNGHLQTTQMLLE-NGAKVNA 527
                 8************99******.8****96 PP

  == domain 4  score: 19.2 bits;  conditional E-value: 3.9e-07
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvna 31 
                 n++t+Lh+Aar+g++ei+ +L+  +gad++a
  EEA21590.1 531 NQMTALHVAARQGDVEIAGLLVS-YGADIDA 560
                 679********************.*****85 PP

  == domain 5  score: 17.8 bits;  conditional E-value: 1.1e-06
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvn 30 
                 +t+Lh+A++ g +++v++Ll+ + a+++
  EEA21590.1 566 MTALHYACEGGFVNVVDLLLR-NKANID 592
                 69*******************.899987 PP

  == domain 6  score: 2.2 bits;  conditional E-value: 0.13
       Ank_3   3 etpLhlAarsgnleivkfLle 23 
                 +tpL +Aa  g l  v++L +
  EEA21590.1 599 RTPLICAAATGQLLAVQLLMN 619
                 8************88998876 PP

  == domain 7  score: 17.7 bits;  conditional E-value: 1.2e-06
       Ank_3   2 GetpLhlAarsgnleivkfLle 23 
                 G+t+Lh+Aa +g++eiv++L  
  EEA21590.1 631 GMTALHWAAYNGHVEIVDYLTS 652
                 89*****************976 PP

  == domain 8  score: 21.7 bits;  conditional E-value: 6.1e-08
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadv 29 
                 G+tpLhlAa++  +++v+fL++ k +++
  EEA21590.1 665 GRTPLHLAAMNSQFAVVEFLIR-KSCPL 691
                 9*********************.77765 PP

  == domain 9  score: 18.6 bits;  conditional E-value: 6.2e-07
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadv 29 
                 G ++Lh+A++++n+eiv++Ll   ga++
  EEA21590.1 698 GLNALHYACKADNTEIVRLLLT-SGANI 724
                 889*******************.89998 PP

  == domain 10  score: 4.0 bits;  conditional E-value: 0.034
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadv 29 
                 + p+h+ a  g++ +v++L+e kga +
  EEA21590.1 733 QRPIHMSAAEGSVGLVRLLCE-KGASL 758
                 679******************.99986 PP

  == domain 11  score: 5.7 bits;  conditional E-value: 0.0093
       Ank_3   5 pLhlAarsgnleivkfLlenkgadv 29 
                 +L +Aar+g+++ v+ Ll+ +g ++
  EEA21590.1 768 ALCVAARNGHVAAVQTLLD-FGSPL 791
                 6668***************.88776 PP

  == domain 12  score: 5.5 bits;  conditional E-value: 0.011
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadv 29 
                 +pL lAa+ g +++v +L++ +ga v
  EEA21590.1 803 SPLCLAAKGGYFPVVSLLIK-HGASV 827
                 89999***************.89987 PP

  == domain 13  score: 8.0 bits;  conditional E-value: 0.0018
       Ank_3   2 GetpLhlAarsgnleivkfLle 23 
                 G+tp  +Aa +g+++++++++ 
  EEA21590.1 834 GWTPARYAAYYGHPDVLELIVA 855
                 9**************9888875 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       3.9   1.2e+04      11      36 ..     141     161 ..     131     165 .. 0.70
   2 !   27.7   0.6   7.9e-10   2.4e-06      17      56 .]     434     473 ..     425     473 .. 0.93
   3 !   25.7   0.2   3.4e-09     1e-05       1      42 [.     452     492 ..     452     503 .. 0.83
   4 !    6.6   0.1    0.0033       9.8      11      45 ..     494     528 ..     489     531 .. 0.83
   5 !   24.8   0.1   6.5e-09     2e-05       1      47 [.     518     563 ..     518     565 .. 0.96
   6 !   22.4   0.1   3.6e-08   0.00011       1      54 [.     551     603 ..     551     605 .. 0.93
   7 !   26.0   0.1   2.8e-09   8.4e-06      12      56 .]     627     672 ..     625     672 .. 0.95
   8 !    9.6   0.0   0.00038       1.1       8      37 ..     660     686 ..     653     698 .. 0.75
   9 !   19.2   0.1   3.7e-07    0.0011      11      41 ..     693     723 ..     686     732 .. 0.79
  10 !   14.2   0.0   1.4e-05     0.042      17      50 ..     733     766 ..     723     769 .. 0.88
  11 !    7.6   0.1    0.0017         5      19      44 ..     768     793 ..     765     795 .. 0.89
  12 !   23.8   0.0   1.4e-08   4.1e-05      15      56 .]     802     841 ..     793     841 .. 0.91
  13 ?    4.6   0.0     0.014        43      22      43 ..     840     862 ..     840     871 .. 0.80

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 3.9
       Ank_5  11 rldgggntpLhvAakygaadvvrlLl 36 
                 +l     + L +A+ +++++  ++Ll
  EEA21590.1 141 AL-----NLLLQACQCRSSTEQLELL 161
                 44.....8888999999998777776 PP

  == domain 2  score: 27.7 bits;  conditional E-value: 7.9e-10
       Ank_5  17 ntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                  ++L+vAa++g  d++ lL+ ++a ln td++G+tal+lA
  EEA21590.1 434 RNALMVAAHCGKDDIADLLIQNNAQLNRTDASGSTALHLA 473
                 29************************************98 PP

  == domain 3  score: 25.7 bits;  conditional E-value: 3.4e-09
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadl 42 
                 L+++  a++nr+d  g t+Lh+Aa++g+ +vv+lL+++  d+
  EEA21590.1 452 LIQNN-AQLNRTDASGSTALHLAASRGHVSVVELLVMEAIDI 492
                 67887.*****************************9766555 PP

  == domain 4  score: 6.6 bits;  conditional E-value: 0.0033
       Ank_5  11 rldgggntpLhvAakygaadvvrlLlargadlnlt 45 
                 ++ + + t+L v+a++g+++  ++Ll++ga  n++
  EEA21590.1 494 AETRLRRTALWVSANNGHLQTTQMLLENGAKVNAR 528
                 5555566**********************999887 PP

  == domain 5  score: 24.8 bits;  conditional E-value: 6.5e-09
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltds 47 
                 Lle+g a vn++  + +t+LhvAa++g  +++ lL+ +gad++++d+
  EEA21590.1 518 LLENG-AKVNARADNQMTALHVAARQGDVEIAGLLVSYGADIDARDA 563
                 89***.***************************************97 PP

  == domain 6  score: 22.4 bits;  conditional E-value: 3.6e-08
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltald 54 
                 L+++g ad++++d   +t+Lh+A+++g  +vv lLl + a++++  s+ +t+l 
  EEA21590.1 551 LVSYG-ADIDARDASMMTALHYACEGGFVNVVDLLLRNKANIDVAGSERRTPLI 603
                 77888.99999999999**********************************996 PP

  == domain 7  score: 26.0 bits;  conditional E-value: 2.8e-09
       Ank_5  12 ldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltaldlA 56 
                  d+gg+t+Lh+Aa++g+ ++v +L    +  l  t+ +G+t+l+lA
  EEA21590.1 627 VDEGGMTALHWAAYNGHVEIVDYLTsHSRGLLASTNVQGRTPLHLA 672
                 589***********************99999999**********98 PP

  == domain 8  score: 9.6 bits;  conditional E-value: 0.00038
       Ank_5   8 dvnrldgggntpLhvAakygaadvvrlLla 37 
                 ++n     g tpLh+Aa +  + vv++L+ 
  EEA21590.1 660 STNV---QGRTPLHLAAMNSQFAVVEFLIR 686
                 4444...566******************94 PP

  == domain 9  score: 19.2 bits;  conditional E-value: 3.7e-07
       Ank_5  11 rldgggntpLhvAakygaadvvrlLlargad 41 
                 +++  g ++Lh+A+k+ + ++vrlLl  ga+
  EEA21590.1 693 ARCAAGLNALHYACKADNTEIVRLLLTSGAN 723
                 5666799*******************44443 PP

  == domain 10  score: 14.2 bits;  conditional E-value: 1.4e-05
       Ank_5  17 ntpLhvAakygaadvvrlLlargadlnltdsrGl 50 
                 + p+h++a  g+  +vrlL++ ga+l ++d++G+
  EEA21590.1 733 QRPIHMSAAEGSVGLVRLLCEKGASLEVRDAEGD 766
                 48******************************95 PP

  == domain 11  score: 7.6 bits;  conditional E-value: 0.0017
       Ank_5  19 pLhvAakygaadvvrlLlargadlnl 44 
                 +L+vAa++g+   v+ Ll++g+ l l
  EEA21590.1 768 ALCVAARNGHVAAVQTLLDFGSPLHL 793
                 8*****************99988766 PP

  == domain 12  score: 23.8 bits;  conditional E-value: 1.4e-08
       Ank_5  15 ggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 +  +pL++Aak+g+++vv lL+++ga+   +d++G+t+  +A
  EEA21590.1 802 D--SPLCLAAKGGYFPVVSLLIKHGASVLSKDEMGWTPARYA 841
                 3..8**********************************9998 PP

  == domain 13  score: 4.6 bits;  conditional E-value: 0.014
       Ank_5  22 vAakygaadvvrlLl.argadln 43 
                 +Aa+yg++dv++l++ a++++  
  EEA21590.1 840 YAAYYGHPDVLELIVaAEPSAVS 862
                 7**************88887765 PP

>> DUF1612  Protein of unknown function (DUF1612)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1   9.7e-05      0.29      61     118 ..     662     719 ..     633     723 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 9.7e-05
     DUF1612  61 rqrgktasHLaalnlglkavrrerrrardretRllailealeaaaeaglkeldRlslA 118
                   +g t  HLaa+n     v+   r++   e R +a l+al+ a +a   e+ Rl l 
  EEA21590.1 662 NVQGRTPLHLAAMNSQFAVVEFLIRKSCPLEARCAAGLNALHYACKADNTEIVRLLLT 719
                 457999*************************************************885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1166 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       535  (0.0298399); expected 358.6 (0.02)
Passed bias filter:                      419  (0.02337); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.86u 0.33s 00:00:01.19 Elapsed: 00:00:00.51
# Mc/sec: 6868.20
//
Query:       EEA21591.1  [L=265]
Description: proliferating cell nuclear antigen (PCNA) [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.1e-54  181.1   3.2    1.1e-53  180.3   3.2    1.4  1  PCNA_N    Proliferating cell nuclear antigen, N-terminal doma
      4e-49  166.0   0.1    2.6e-48  163.4   0.0    2.0  2  PCNA_C    Proliferating cell nuclear antigen, C-terminal doma
      1e-07   31.7   0.1    1.3e-07   31.3   0.1    1.1  1  Rad9      Rad9
    8.9e-06   25.0   0.3    0.00091   18.4   0.3    2.0  1  Rad1      Repair protein Rad1/Rec1/Rad17
    0.00068   18.8   0.3     0.0051   16.0   0.1    2.0  2  Hus1      Hus1-like protein


Domain annotation for each model (and alignments):
>> PCNA_N  Proliferating cell nuclear antigen, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  180.3   3.2   3.1e-57   1.1e-53       1     124 [.       1     124 [.       1     125 [. 0.98

  Alignments for each domain:
  == domain 1  score: 180.3 bits;  conditional E-value: 3.1e-57
                 CEEEEESSHHHHHHHHHHHTTTCSEEEEEEETTEEEEEEE-TTSSEEEEEEEEGGGSSEEEESS-EEEEEEHHHHHHHHTTSTTTSEEEEEEETTSSEE CS
      PCNA_N   1 mlearleqasllkklleaikdlvneanfdcddsGislqalDsshvaLvslelrsegfekyrCDrnlalgvnlnslskilkcannedsvtlkaedeadtl 99 
                 m+earleqa llk++++aikdlv++ nfdc+dsGi lqa+D+shvaLvs+ l++++f+ yrCDr +alg+nl sl+k+l+ a+ned++tlkaed++d++
  EEA21591.1   1 MFEARLEQAGLLKRVVDAIKDLVQDCNFDCNDSGIALQAMDNSHVALVSMMLNADAFSPYRCDRTVALGINLLSLTKVLRAAQNEDILTLKAEDSPDVV 99 
                 9************************************************************************************************** PP

                 EEEEEECTSSEEEEEEEEEEEBGCE CS
      PCNA_N 100 alvfesekkdkiaeydlklklidld 124
                 +l+fes+++d+ +eyd+kl++id++
  EEA21591.1 100 NLMFESSETDRLSEYDIKLMDIDQE 124
                 ********************99983 PP

>> PCNA_C  Proliferating cell nuclear antigen, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.18   6.5e+02      55     116 ..      44     104 ..       9     115 .. 0.69
   2 !  163.4   0.0   7.3e-52   2.6e-48       2     128 .]     128     260 ..     127     260 .. 0.93

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.18
                 EE--BEESSSGGGCBEEEESS-EEEEEEHHHHHHHGGGGGC-SEEEEEEETTSEEEEEEEET CS
      PCNA_C  55 vlkqvkdvdkeeeavklelkepvtltfalkYlaeftkatsLservtlslssevPlvveykik 116
                  ++ v+++ + + ++  + +++v l   l  l+++ +a+   +  tl+ +++ P vv+   +
  EEA21591.1  44 HVALVSMMLNADAFSPYRCDRTVALGINLLSLTKVLRAAQNEDILTLK-AEDSPDVVNLMFE 104
                 344566777778888888888888888888888888888888877776.5777777776555 PP

  == domain 2  score: 163.4 bits;  conditional E-value: 7.3e-52
                 ---SS-SEEEEEEHHHHHHHHHHHTTT-SEEEEEEETTEEEEEEEETTEEEEEEE--BEESSSGGGCBEEEESS-EEEEEEHHHHHHHGGGGGC-SEEE CS
      PCNA_C   2 ipdseydavvklpssefaricrdlsqlsdsvvisvtkegvkfsasGdiGsasivlkqvkdvdkeeeavklelkepvtltfalkYlaeftkatsLservt 100
                 ipd++y a+v++ps+ef+ricrdl  ls+svvi +tkeg+kfs++GdiG+++++++q+++v+++ + v ++l+epv ltf+lkYl++f kat+Ls +v+
  EEA21591.1 128 IPDTDYAATVSMPSVEFQRICRDLNALSESVVIEATKEGIKFSCQGDIGNGAVTIRQHTNVEDPTKNVSIQLTEPVALTFSLKYLVNFCKATALSGQVK 226
                 9************************************************************************************************** PP

                 EEEETTSEEEEEEEET......TCEEEEEEE-BS CS
      PCNA_C 101 lslssevPlvveykik......dvgllayllakk 128
                 l ls+evPl vey+++        g+l+++la+k
  EEA21591.1 227 LCLSQEVPLQVEYSLAgsagsaASGHLRFFLAPK 260
                 **************97322222457888888875 PP

>> Rad9  Rad9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.3   0.1   3.7e-11   1.3e-07       2     229 ..      13     244 ..      12     247 .. 0.83

  Alignments for each domain:
  == domain 1  score: 31.3 bits;  conditional E-value: 3.7e-11
        Rad9   2 aralqclsrigdelyleisedglelrtvnssrSayalvtlkksfFdkyekevseqirckilvKsvlsvfrslsakektvekvkisidekksrlivqll. 99 
                  r++ ++  + ++ +++ ++ g++l+++++s+ a +++ l+ + F+ y  + + ++ + i++ s+ +v+r  +a+++ +  ++++ +++   + + +  
  EEA21591.1  13 KRVVDAIKDLVQDCNFDCNDSGIALQAMDNSHVALVSMMLNADAFSPY--RCDRTVALGINLLSLTKVLR--AAQNEDI--LTLKAEDSPDVVNLMFEs 105
                 57777777888899**********************************..999****************9..4445555..445554444334444431 PP

        Rad9 100 CkhgvkkthkisledseslkavfdkettpsklriksrvLsdllehfsssleeitielakervllksyeeeekdnkkalstelsideeeFeqyqlaedve 198
                  + +   ++ i+l d ++ ++ +     + +++++s  ++ +   ++   e + ie++ke ++++   + +++     + + + d+    ++ql+e v+
  EEA21591.1 106 SETDRLSEYDIKLMDIDQEHLAIPDTDYAATVSMPSVEFQRICRDLNALSESVVIEATKEGIKFSCQGDIGNGAVTIRQHTNVEDPTKNVSIQLTEPVA 204
                 45677789************99999999***********************************9888877777743333333447788999******** PP

        Rad9 199 itlslkefk.........allvfaeslsaslslafdeaGk 229
                 +t+slk +          + + ++ s +++l+++++ aG+
  EEA21591.1 205 LTFSLKYLVnfckatalsGQVKLCLSQEVPLQVEYSLAGS 244
                 ******9988888888888889999999999999999986 PP

>> Rad1  Repair protein Rad1/Rec1/Rad17
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.3   2.5e-07   0.00091     132     261 ..      99     227 ..       1     237 [. 0.69

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 2.5e-07
        Rad1 132 LvliLee..agvtttcelsTyepeedldleldrqevvlkvilkselLhsalteLdatskklkilassekkapvfalsakgelgssevefpneksvlekf 228
                  +l++e   ++ + + +++ +++ ++  l   ++  +++v + s  ++ + ++L+a s+++ i a++e     +++s +g++g+  v + +  +v +  
  EEA21591.1  99 VNLMFESseTDRLSEYDIKLMDI-DQEHLAIPDTDYAATVSMPSVEFQRICRDLNALSESVVIEATKE----GIKFSCQGDIGNGAVTIRQHTNVEDPT 192
                 55555553344444444555555.55677888999*****************************9996....89***************9999987755 PP

        Rad1 229 evs.sl.sessessYkfallkkaakalalssKvsl 261
                 + + ++  e++   + +++l +  ka+als  v+l
  EEA21591.1 193 KNVsIQlTEPVALTFSLKYLVNFCKATALSGQVKL 227
                 44434458888888****************88876 PP

>> Hus1  Hus1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.1   1.4e-06    0.0051       3     112 ..       2     105 ..       1     167 [. 0.80
   2 ?    1.7   0.0     0.031   1.1e+02      12      51 ..     143     182 ..     133     247 .. 0.61

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 1.4e-06
        Hus1   3 FkaqltdaetlkkvlqslsklgkecilrltpeklrfiiiteaddgvqvwaqlqvdaiFeeyeieSndeneInlevdlaaLlraLksaeaaksvqlrLtk 101
                 F a+l++a +lk+v+ +++ l ++c    +++ + ++ +  +++ v ++  +   + F+ y+++     +++l ++l +L ++L+ a++   ++l+   
  EEA21591.1   2 FEARLEQAGLLKRVVDAIKDLVQDCNFDCNDSGIALQAM--DNSHVALVSMMLNADAFSPYRCD----RTVALGINLLSLTKVLRAAQNEDILTLKAED 94 
                 7899999********************************..899999999999999*******7....478******************9888887655 PP

        Hus1 102 kgrvplLalei 112
                   +v  L +e 
  EEA21591.1  95 SPDVVNLMFES 105
                 55555555555 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.031
        Hus1  12 tlkkvlqslsklgkecilrltpeklrfiiiteaddgvqvw 51 
                 ++++++  l++l   +++  t+e + f ++ + ++g   +
  EEA21591.1 143 EFQRICRDLNALSESVVIEATKEGIKFSCQGDIGNGAVTI 182
                 7889999999999999999999999999988755554433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (265 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       515  (0.0287244); expected 358.6 (0.02)
Passed bias filter:                      454  (0.0253221); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.47
# Mc/sec: 1680.13
//
Query:       EEA21592.1  [L=325]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
      0.068   12.9   0.3       0.32   10.8   0.0    2.3  2  DUF5353         Family of unknown function (DUF5353)


Domain annotation for each model (and alignments):
>> DUF5353  Family of unknown function (DUF5353)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.1      0.37   6.7e+03      17      54 ..      20      29 ..       7      36 .. 0.48
   2 ?   10.8   0.0   1.8e-05      0.32       3      31 ..     112     140 ..     110     150 .. 0.90

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 0.37
     DUF5353 17 lsagLGfgAYrkyarGeLtwkvvglwagavGafavgdy 54
                ++                             ++++  y
  EEA21592.1 20 AAI----------------------------ILGLESY 29
                222............................3344444 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 1.8e-05
     DUF5353   3 dnpvvvgNavlvavlsagLGfgAYrkyar 31 
                 + pv+++  v++++ s +L+f A++ y +
  EEA21592.1 112 TRPVLIAIPVIITIGSMILAFLAWKLYDE 140
                 67************************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (325 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1090  (0.0607954); expected 358.6 (0.02)
Passed bias filter:                      395  (0.0220313); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 2086.96
//
Query:       EEA21593.1  [L=168]
Description: translocon protein Sec61beta, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.5e-17   62.6   0.8    3.8e-17   62.0   0.8    1.3  1  Sec61_beta  Sec61beta family


Domain annotation for each model (and alignments):
>> Sec61_beta  Sec61beta family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.0   0.8   2.1e-21   3.8e-17       1      41 []     120     160 ..     120     160 .. 0.97

  Alignments for each domain:
  == domain 1  score: 62.0 bits;  conditional E-value: 2.1e-21
                 XXXXXXXXXX----SS-B-THHHHHHHHHHHHHHHHHTSS- CS
  Sec61_beta   1 SsaGLlryyeedapgikidPkvVlvlsvafiasVilLhila 41 
                 Ss ++l+ y++++pg+++dP+vVlvls++fi+sV+ Lh++a
  EEA21593.1 120 SSGTMLKLYTDESPGLRVDPVVVLVLSLGFIFSVVGLHVIA 160
                 89************************************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (168 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       570  (0.0317921); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1166.15
//
Query:       EEA21594.1  [L=369]
Description: transposable element tc1 transposase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.4e-13   48.5   0.1    2.1e-12   47.0   0.1    1.8  1  DDE_3          DDE superfamily endonuclease
    6.5e-10   39.1   0.5    1.7e-09   37.8   0.5    1.7  1  HTH_Tnp_Tc3_2  Transposase
     0.0015   18.3   1.6     0.0062   16.3   0.2    2.7  3  HTH_23         Homeodomain-like domain
     0.0078   16.1   0.0      0.022   14.7   0.0    1.8  1  HTH_12         Ribonuclease R winged-helix domain
     0.0092   15.7   0.1      0.023   14.5   0.1    1.6  1  HTH_38         Helix-turn-helix domain
  ------ inclusion threshold ------
      0.012   16.0   0.1         13    6.3   0.0    3.2  3  DUF4350        Domain of unknown function (DUF4350)
      0.014   16.0  11.1       0.14   12.8   0.6    3.7  4  HTH_32         Homeodomain-like domain
      0.034   13.8   1.2          7    6.4   0.1    3.0  2  HTH_33         Winged helix-turn helix
      0.042   13.9   0.0        9.1    6.5   0.0    3.0  3  HTH_7          Helix-turn-helix domain of resolvase
       0.18   12.0   0.0       0.35   11.1   0.0    1.4  1  DUF2774        Protein of unknown function (DUF2774)
       0.21   11.3   0.5       0.54   10.0   0.0    2.0  2  Sigma70_r4_2   Sigma-70, region 4


Domain annotation for each model (and alignments):
>> DDE_3  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.0   0.1   1.3e-15   2.1e-12      76     145 ..     259     324 ..     244     325 .. 0.85

  Alignments for each domain:
  == domain 1  score: 47.0 bits;  conditional E-value: 1.3e-15
       DDE_3  76 lqakkivlilDnasiHkseslrelveeeadrlellylPpySPelNpiEivwsklkrellkrrsfksldeL 145
                 +q++ + l  D+a+ H s++ ++ ++e   ++  +y+P+ SP+lNpiE vw+++k+++++  ++++ ++L
  EEA21594.1 259 QQSIYLQLMQDGAPGHASKETKKELQE--RNIYPIYWPAFSPDLNPIEAVWNWMKDWIQE--QYPNDEQL 324
                 3444666788*****************..******************************9..66666665 PP

>> HTH_Tnp_Tc3_2  Transposase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.8   0.5     1e-12   1.7e-09       8      72 .]     102     163 ..      98     163 .. 0.92

  Alignments for each domain:
  == domain 1  score: 37.8 bits;  conditional E-value: 1e-12
  HTH_Tnp_Tc3_2   8 vrkdPritlreLanelkeeGksvsreTirrrLrkaglkkrkprkkplLskknrkaRLeFAkehln 72 
                     ++ +r+ + ++++el      + ++   r L+k g+  +k+ +kp+Ls ++++ RL++A+eh+n
     EEA21594.1 102 SKRTRRMPYYKVIREL---DLPIGATALARALKKRGYTRCKALRKPPLSDEHKRVRLAWALEHVN 163
                    5778888888999999...999999999***********************************97 PP

>> HTH_23  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.2   3.8e-06    0.0062       5      35 ..      37      67 ..      33      74 .. 0.91
   2 ?   -1.1   0.1       1.1   1.8e+03      34      41 ..     306     313 ..     304     320 .. 0.80
   3 ?   -4.0   0.0         9   1.5e+04       3      15 ..     351     363 ..     351     367 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 3.8e-06
      HTH_23  5 reRlrillllaeGlsvreIAreLgvsrrTvy 35
                ++R+ril l   G ++ +IA +L++++ +v+
  EEA21594.1 37 DDRIRILTLREAGFTYLQIASQLHITHDQVQ 67
                68*************************9998 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 1.1
      HTH_23  34 vyrwlkry 41 
                 v++w k +
  EEA21594.1 306 VWNWMKDW 313
                 9*****99 PP

  == domain 3  score: -4.0 bits;  conditional E-value: 9
      HTH_23   3 sereRlrilllla 15 
                 s++ R++++ l+ 
  EEA21594.1 351 SMQARCQAVILAE 363
                 5788999887765 PP

>> HTH_12  Ribonuclease R winged-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   1.4e-05     0.022       5      36 ..     112     142 ..     110     144 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.4e-05
      HTH_12   5 kilaesdkpigakeiaeeLkkrgydigeravR 36 
                 k++ e d piga ++a  Lkkrgy    +a+R
  EEA21594.1 112 KVIRELDLPIGATALARALKKRGYTR-CKALR 142
                 6999********************86.67777 PP

>> HTH_38  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.1   1.4e-05     0.023       4      31 ..      33      60 ..      31      64 .. 0.91

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 1.4e-05
      HTH_38  4 hLsleeReeIerllaeGlslreIArrLg 31
                +L+ ++R +I +l+++G ++ +IA +L+
  EEA21594.1 33 RLNRDDRIRILTLREAGFTYLQIASQLH 60
                8999*********************997 PP

>> DUF4350  Domain of unknown function (DUF4350)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   0.0     0.008        13       2      52 ..      13      66 ..      12      69 .. 0.76
   2 ?   -1.3   0.0       1.8     3e+03      46      60 ..      86     100 ..      82     101 .. 0.83
   3 ?    5.6   0.0     0.014        22       4      27 ..     120     144 ..     119     152 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.008
     DUF4350  2 kspnGtralaelLeaqGvevrrvrkp.fd..alegedgtllvvapdlrlteeel 52
                ++p+G+r +a+  e++ +++r  r+       l +++ t+l +a++l++t++++
  EEA21594.1 13 AAPEGAREAASGGESKPYSTRLNRDDrIRilTLREAGFTYLQIASQLHITHDQV 66
                68999999999999999999755554233345555677*************887 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.8
     DUF4350  46 rlteeelaallewva 60 
                  l+ee+++++ +w +
  EEA21594.1  86 KLSEEDVDRVIDWIS 100
                 6899********976 PP

  == domain 3  score: 5.6 bits;  conditional E-value: 0.014
     DUF4350   4 pnGtralaelLeaqGvev.rrvrkp 27 
                 p G+ ala+ L+++G++  ++ rkp
  EEA21594.1 120 PIGATALARALKKRGYTRcKALRKP 144
                 6799************986666665 PP

>> HTH_32  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.0    0.0083        14      15      68 ..      16      65 ..      11      71 .. 0.74
   2 ?   12.8   0.6   8.8e-05      0.14      18      56 ..      76     130 ..      68     137 .. 0.66
   3 ?    2.6   0.7      0.13   2.1e+02      17      56 ..     130     173 ..     121     181 .. 0.67
   4 ?   -2.8   0.1       6.4     1e+04      53      60 ..     311     318 ..     306     336 .. 0.47

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0083
      HTH_32 15 egLkdrprrg..rpr..klsdevrariiallreeprWsprqlaarlaeregvkvShst 68
                eg ++++++g  +p   +l+ + r ri+ l+ e+  +++ q+a +l       + h +
  EEA21594.1 16 EGAREAASGGesKPYstRLNRDDRIRILTLR-EA-GFTYLQIASQL------HITHDQ 65
                566666666664553778*************.77.8********99......333433 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 8.8e-05
      HTH_32  18 kdrprrgrprklsdevrariiallreep.................rWsprqlaarl 56 
                  +++ rgr++kls+e ++r+i+++   +                   ++  la++l
  EEA21594.1  76 TPKKARGRTPKLSEEDVDRVIDWIS-SSkrtrrmpyykvireldlPIGATALARAL 130
                 588999******************4.332455444444444333333555555555 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.13
      HTH_32  17 Lkdrprrg........rprklsdevrariiallreeprWsprqlaarl 56 
                 Lk r   g        +p+ lsde+++  +a++ e+  W+ +q  + l
  EEA21594.1 130 LKKR---GytrckalrKPP-LSDEHKRVRLAWALEHVNWTIEQWNRIL 173
                 4444...222223341444.999999999999977889*999976655 PP

  == domain 4  score: -2.8 bits;  conditional E-value: 6.4
      HTH_32  53 aarlaere 60 
                  ++++e++
  EEA21594.1 311 KDWIQEQY 318
                 33443333 PP

>> HTH_33  Winged helix-turn helix
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.1     0.012        20      19      54 ..      58      93 ..      44      97 .. 0.85
   2 ?    6.4   0.1    0.0043         7      23      53 ..     122     152 ..     110     155 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.012
      HTH_33 19 gvsysvsgvyrlLkrlGfsyqkPrprapkqdpeaqe 54
                ++++++ +v    + +  +++k+r r pk ++e ++
  EEA21594.1 58 QLHITHDQVQYTCQSQQATPKKARGRTPKLSEEDVD 93
                567888999999999999**************9987 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.0043
      HTH_33  23 svsgvyrlLkrlGfsyqkPrprapkqdpeaq 53 
                   + + r Lk+ G++  k+ +++p  d++++
  EEA21594.1 122 GATALARALKKRGYTRCKALRKPPLSDEHKR 152
                 55677899********************986 PP

>> HTH_7  Helix-turn-helix domain of resolvase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.0    0.0056       9.1       7      37 ..      35      65 ..      33      66 .. 0.84
   2 ?    3.9   0.0     0.036        58       1      15 [.      82      96 ..      82     100 .. 0.94
   3 ?   -3.4   0.0       6.7   1.1e+04      21      35 ..     195     209 ..     193     210 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0056
                -HHHHGGGGSSTTTT--STTTSSSS---SSS CS
       HTH_7  7 skndinrvvkLleeGisiskIAkevnisRsT 37
                +++d  r+++L+e+G +  +IA ++ i+  +
  EEA21594.1 35 NRDDRIRILTLREAGFTYLQIASQLHITHDQ 65
                56666799*****************999655 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.036
                S---SS-HHHHGGGG CS
       HTH_7  1 GRpsklskndinrvv 15
                GR +kls++d +rv+
  EEA21594.1 82 GRTPKLSEEDVDRVI 96
                9************97 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 6.7
                 T--STTTSSSS---S CS
       HTH_7  21 GisiskIAkevnisR 35 
                 G+   +++ ++ ++R
  EEA21594.1 195 GEELDDTCLRTSVAR 209
                 666678899999998 PP

>> DUF2774  Protein of unknown function (DUF2774)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00021      0.35       3      31 ..      39      67 ..      37      83 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00021
     DUF2774  3 kvqvhflhesgknFveIAkkldirakdva 31
                ++++ +l+e+g+ + +IA +l i+  +v 
  EEA21594.1 39 RIRILTLREAGFTYLQIASQLHITHDQVQ 67
                578999*****************988775 PP

>> Sigma70_r4_2  Sigma-70, region 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00033      0.54      17      40 ..      41      63 ..      32      69 .. 0.77
   2 ?   -2.3   0.3       2.3   3.8e+03      45      53 ..     124     132 ..     123     132 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00033
                  HHHHHHHTS---HHHHHHHHT--H CS
  Sigma70_r4_2 17 eifllryleglsykEIAellgise 40
                  +i++l ++ g++y +IA++l+i+ 
    EEA21594.1 41 RILTL-REAGFTYLQIASQLHITH 63
                  46666.89*************985 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 2.3
                   HHHHHHHHH CS
  Sigma70_r4_2  45 srlsRArkk 53 
                   ++l+RA+kk
    EEA21594.1 124 TALARALKK 132
                   6799***98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (369 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       574  (0.0320152); expected 358.6 (0.02)
Passed bias filter:                      449  (0.0250432); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.46
# Mc/sec: 2431.86
//
Query:       EEA21595.1  [L=675]
Description: urea transporter (Dur3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      8e-16   57.9  31.7    1.3e-15   57.2  31.7    1.3  1  SSF       Sodium:solute symporter family


Domain annotation for each model (and alignments):
>> SSF  Sodium:solute symporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.2  31.7   7.5e-20   1.3e-15       1     360 [.      50     413 ..      50     455 .. 0.79

  Alignments for each domain:
  == domain 1  score: 57.2 bits;  conditional E-value: 7.5e-20
         SSF   1 yflagrsltgfvlglslaasnisaasfvGlaGavaasGlav.vllelgalllvlllllllaerlr.nagalTlpdylskRfkgkrilvylsalslllvi 97 
                 + +agr + +  ++ ++ +s   aa ++  + +++ +G+++ + ++ ga++ +ll   l +e  r   +a T+ +++++R++       + ++  l+  
  EEA21595.1  50 FSTAGRTVKSGLVASAVVSSWTWAATLLQSSTVAYEYGVSGpFYYAAGATVQILLFATLAIELKRrAPNAHTFLEVIRARYGTVV--HCVFIVFCLMTN 146
                 5689***********************************98356899999999999888888766467**************977..555555666666 PP

         SSF  98 tlklsvdlvggaklielalGlnyetavlllaaltalYtviGGllAvvytdtiqavlmlvg..alilliivllevGgleslveklkeaapkv..vdlltp 192
                 +l  +  l gg + ++ + G+   +a +ll + ++lYtv+GG+ A+  td + +++++v   ++    ++++ + g    v  + +aa k   vd + +
  EEA21595.1 147 VLVTAMLLTGGSAVLNALTGMPTPAACFLLPIGVVLYTVFGGIKATFITDYLHTIVIVVIifTFAFNTYAVSPILGSPGKVYDILTAAAKAnpVDGNSG 245
                 666667799********************************************9887554003334445555554555555555555554447999999 PP

         SSF 193 dslkllrdpltalslwlglv..lGvagl.philvRflaakdakailkgvlkltivlilvligmisiilfaiklagavpkavgtevgvsniaypeLvvkl 288
                 +s+ ++++   ++ + + lv  +G++ l      + +aa+ ++a    v+ ++ ++++  + + +++l a +l g   ++  +++ ++ +++p  +v++
  EEA21595.1 246 GSYLTMHSREGGIFFVINLVgnFGTVFLdNGYYNKAIAASPVHAFPGYVIGGLCWFAIPWLCATTMGLAALALQGN--AILSPTDVTAGLVLPYAAVEM 342
                 9987777777777665555444777776666788999999999998888889****************99999988..999999999************ PP

         SSF 289 lpnllaGlllavmlAaimstltslllsassaftkDlYkkirrkasakekelvgvsriivlvvislaillavq 360
                 ++ + a     +++ a+ s  +++l++ ss+ t D++++ ++   ak k+lv++s ++ +v + ++   a  
  EEA21595.1 343 MGYGGAVATTLMVFMAVTSAFSAQLIAVSSVCTYDIFQAYIQPS-AKGKKLVWISHMACVVYALVMAGFATG 413
                 *998777666677889***********************99999.9***********999998887655544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (675 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1091  (0.0608511); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.69u 0.30s 00:00:00.99 Elapsed: 00:00:00.46
# Mc/sec: 4371.29
//
Query:       EEA21596.1  [L=350]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.7e-51  173.6   0.0    7.3e-51  173.3   0.0    1.1  1  LIDHydrolase   Lipid-droplet associated hydrolase
    0.00057   20.6   0.0     0.0007   20.3   0.0    1.3  1  Abhydrolase_6  Alpha/beta hydrolase family
     0.0007   18.9   0.0       0.42    9.8   0.0    2.2  2  Hydrolase_4    Serine aminopeptidase, S33
     0.0022   17.5   0.0     0.0031   17.1   0.0    1.2  1  DUF900         Alpha/beta hydrolase of unknown function (DUF9
  ------ inclusion threshold ------
      0.016   14.9   0.0      0.029   14.0   0.0    1.4  1  Abhydrolase_1  alpha/beta hydrolase fold
      0.025   14.3   0.0      0.042   13.5   0.0    1.3  1  PGAP1          PGAP1-like protein
      0.058   12.6   0.0      0.082   12.1   0.0    1.3  1  LCAT           Lecithin:cholesterol acyltransferase
       0.12   12.2   0.0        1.2    9.0   0.0    2.1  2  Ser_hydrolase  Serine hydrolase


Domain annotation for each model (and alignments):
>> LIDHydrolase  Lipid-droplet associated hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  173.3   0.0   3.3e-54   7.3e-51       2     250 ..      20     290 ..      19     306 .. 0.91

  Alignments for each domain:
  == domain 1  score: 173.3 bits;  conditional E-value: 3.3e-54
  LIDHydrolase   2 kilivlipGNPGlveFYetFlsllsekl.....npelevlgishaGfeleeeekeakenekvfsLedQiehkedflkellek....aksekdvklil 89 
                   +++i+++pGNPGlve+Y +Flsll++ l     + ++++ g s+aGfe e+++ ++++ +k++++ +Q+ +  d l+e+++       +e++ k+il
    EEA21596.1  20 PYHIFFLPGNPGLVEYYAKFLSLLHSALnqapsTTQFNIAGCSYAGFETENSS-SKENDGKLYDITEQVTFCLDQLQEYINGgtkdMLAETKPKVIL 115
                   689*************************9999999***************999.9999**********************88887767899****** PP

  LIDHydrolase  90 vGHSvGaYialevlkrlsers.........ikkvvlLfPtiediakSpngkkltkllaylpflalvvglllrvlkllPesvkslliklvlgkssspk 177
                   +GHS G++++ e++krl ++s         i++ + LfP i d+akSp+g k++ + a  ++l  +++++++ +  lP s+++ +++ ++   s+ +
    EEA21596.1 116 IGHSFGTFVIAEIMKRLYTSSaqdekqnyeIIGNIHLFPPIPDLAKSPRGVKAAGV-ATWKYLPSIMSFIANAVYNLPLSWSNAVVRYMTAFPSD-S 210
                   ***************999988999*******************************9.999***************************99999998.5 PP

  LIDHydrolase 178 eavettlkfvkspevvrqalhlakdEmeeikeddeeed..vllkknkeka.....lvfyfgkkDhWvpeetrdelkellg 250
                   +a+ tt +f+ s+++v+qal+l k E++eik   +ee   ++ + +k+++     + ++fg +DhWv +e rd+ + ++ 
    EEA21596.1 211 DALYTTRQFFGSRTGVAQALYLVKFEFDEIKLSRWEEAfrSIASYHKHQQqkkfpIRIFFGANDHWVDNELRDAFMYKYC 290
                   6******************************9999964222333333333678*******************99877665 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0   3.1e-07    0.0007      55     152 ..      92     224 ..      17     315 .. 0.61

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 3.1e-07
                    HHHCCTT...........TTSEEEEEETCHHHHHHHHHHCC..............EE.EEES-.............----TTT.......S----T CS
  Abhydrolase_6  55 alldelaa.........gggpvvlvGHSlGGalalaaapla............lvvg.vlldppp...........talpagl.......laaale 110
                    ++l+e ++           ++v+l+GHS+G+++ ++  + +             ++g + l pp                          l+ +++
     EEA21596.1  92 DQLQEYINggtkdmlaeTKPKVILIGHSFGTFVIAEIMKRLytssaqdekqnyEIIGnIHLFPPIpdlaksprgvkA-----AgvatwkyLPSIMS 182
                    3333333334444554447899**********999933333455557777777666666666633555444443332.....03344477888888 PP

                    THHHHHHTT-CCCCHCCH..S-HSCCCCHHHCCCCHCHCCCGHH CS
  Abhydrolase_6 111 lllallallrllawlsre..plprlfladedadaawrarlarla 152
                    +++ +  +l+l  w+++   +++  f +d da ++ r+ +    
     EEA21596.1 183 FIANAVYNLPL-SWSNAVvrYMT-AFPSDSDALYTTRQFFGSRT 224
                    88888888887.88854442233.66666664333333332222 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.8   0.0    0.0015       3.4      74      96 ..     109     131 ..      78     139 .. 0.82
   2 !    9.8   0.0   0.00019      0.42     168     214 ..     240     286 ..     233     292 .. 0.89

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0015
  Hydrolase_4  74 pelplfllGhSmGGliallyllr 96 
                   + +++l+GhS G ++ +++++r
   EEA21596.1 109 TKPKVILIGHSFGTFVIAEIMKR 131
                  44589************999954 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00019
  Hydrolase_4 168 itvrlllelldamkrleeraakitlPllllhGeaDkvvdpeasrely 214
                  i+++ + e+++ +++ ++++++ ++P+ ++ G++D+ vd+e + +++
   EEA21596.1 240 IKLSRWEEAFRSIASYHKHQQQKKFPIRIFFGANDHWVDNELRDAFM 286
                  5666789999******************************9887775 PP

>> DUF900  Alpha/beta hydrolase of unknown function (DUF900)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   0.0   1.4e-06    0.0031      74     139 ..      88     158 ..      71     185 .. 0.74

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 1.4e-06
      DUF900  74 easrdalekllrylatk...ksakkihllaHSmGtwlvlealrqlaieadepavea..kikeviLaAPDid 139
                 ++  d+l++ ++  +++   + + k+ l+ HS Gt++++e ++ l  +  + + ++  +i+++ L+ P  d
  EEA21596.1  88 TFCLDQLQEYINGGTKDmlaETKPKVILIGHSFGTFVIAEIMKRLYTSSAQDEKQNyeIIGNIHLFPPIPD 158
                 5555666666653333333345899********************99877644444569999999987555 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   1.3e-05     0.029       2      89 ..      22     127 ..      21     132 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1.3e-05
                    EEEEE-STTTCGGGGTTGHHHHHHHHT........TSEEEEEEETTSTTSSSTTTGB..........CHHSHHHHHHHHH...HHHHHCTTSSEEE CS
  Abhydrolase_1   2 vlvilhGlpgssdvwaerglapaLakd........gfdvillDlrGvgySspapacin.........ddygtasvaddld...rildalgddkltl 77 
                    ++ +l+G pg  +++a+  + + L  +        +f + +    G+     ++ +++         ++++++ ++++++   + + a    k++l
     EEA21596.1  22 HIFFLPGNPGLVEYYAK--FLSLLHSAlnqapsttQFNIAGCSYAGFETENSSSKENDgklyditeqVTFCLDQLQEYINggtKDMLAETKPKVIL 115
                    68899999997777777..554554445565777889999999999888888888888*********99***********975337777788899* PP

                    EEETHHHHHHHH CS
  Abhydrolase_1  78 vGhSmGGmiala 89 
                    +GhS+G+++ ++
     EEA21596.1 116 IGHSFGTFVIAE 127
                    *******98775 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   1.9e-05     0.042       7     105 ..      23     125 ..      18     140 .. 0.72

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 1.9e-05
       PGAP1   7 VlFvpGnagsykqvrslAseaaeayqelrkllknqnkkeldfftvdfneelsaldGrtlldqaeylndaIkyIlsly......sssekeptsviliGHS 99 
                 + F+pGn g ++    + s  ++a  ++  ++ + n +  ++   ++++  s  + + l d +e +  ++ ++++ y      +   + + +viliGHS
  EEA21596.1  23 IFFLPGNPGLVEYYAKFLSLLHSAL-NQAPSTTQFNIAGCSYAGFETENSSSKENDGKLYDITEQVTFCLDQLQE-YinggtkDMLAETKPKVILIGHS 119
                 6788888888888877777773333.3333333333344889999999999999999999999999999999554.5588876556778899******* PP

       PGAP1 100 mGGiva 105
                 +G +v 
  EEA21596.1 120 FGTFVI 125
                 **9884 PP

>> LCAT  Lecithin:cholesterol acyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   3.7e-05     0.082     114     145 ..     104     135 ..      58     152 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 3.7e-05
        LCAT 114 ealklsgkkvvliaHSmGnllvlyflkwveae 145
                  +l++ + kv+li+HS G  ++ + +k++ + 
  EEA21596.1 104 DMLAETKPKVILIGHSFGTFVIAEIMKRLYTS 135
                 57889999******************997654 PP

>> Ser_hydrolase  Serine hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.0   0.00052       1.2      49      74 ..     105     130 ..      86     140 .. 0.84
   2 ?    0.6   0.0      0.19   4.4e+02     100     131 ..     247     280 ..     212     287 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00052
                    HHHC-STTEEEEEETCHHHHHHHHHH CS
  Ser_hydrolase  49 aveaaeekvvlvAHSlgclavlhaae 74 
                     +++++ kv+l+ HS+g  +++++++
     EEA21596.1 105 MLAETKPKVILIGHSFGTFVIAEIMK 130
                    57888999*************99885 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.19
                    GGGCGCTTS..-SSHHCCHCEEEEETTBTTC-HH CS
  Ser_hydrolase 100 aelaefapl..preklpfpslvvaSenDpyvsfe 131
                    +++++ a +  ++++ +fp +++   nD +v+ e
     EEA21596.1 247 EAFRSIASYhkHQQQKKFPIRIFFGANDHWVDNE 280
                    44555554411467789999*********99866 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (350 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       415  (0.0231469); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2427.86
//
Query:       EEA21597.1  [L=308]
Description: dynein light chain type 1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.4e-23   83.0   0.7    2.4e-23   82.2   0.7    1.3  1  Dynein_light     Dynein light chain type 1
  ------ inclusion threshold ------
       0.12   12.3   0.0       0.43   10.5   0.0    1.9  2  HU-CCDC81_bac_1  CCDC81-like prokaryotic HU domain 1


Domain annotation for each model (and alignments):
>> Dynein_light  Dynein light chain type 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.2   0.7   2.7e-27   2.4e-23      10      68 ..      54     110 ..      49     121 .. 0.92

  Alignments for each domain:
  == domain 1  score: 82.2 bits;  conditional E-value: 2.7e-27
                   -HHHHHHHHHHHHHHHHH-SSHH..HHHHHHHHHHHHHH-S-EEEEEEEEEEEEEEEET CS
  Dynein_light  10 seemqeeaielakealekfkkekekdiaayikkeldkkygptWhciVgksfgssvthek 68 
                   +e+mq+eaie+a+ea+ekf+ ek  dia++ikke+d++ g tWhciVg++fgs+vth  
    EEA21597.1  54 TEDMQQEAIEVATEAMEKFHMEK--DIAQHIKKEFDSRKGATWHCIVGRNFGSFVTHVC 110
                   79****************99999..********************************75 PP

>> HU-CCDC81_bac_1  CCDC81-like prokaryotic HU domain 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   4.8e-05      0.43      17      52 ..      96     131 ..      92     136 .. 0.89
   2 ?   -2.8   0.0      0.66   5.9e+03      42      59 .]     193     210 ..     188     210 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 4.8e-05
  HU-CCDC81_bac_1  17 cVivPglGGFvahyvpArydeeenlflPpkrtigFN 52 
                      c++  ++G Fv+h +   +d +++ f+P +r + + 
       EEA21597.1  96 CIVGRNFGSFVTHVCLEIFDLDTHAFTPGSRALMYS 131
                      888889*************************99765 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.66
  HU-CCDC81_bac_1  42 flPpkrtigFNpqlklnD 59 
                      +l p+  ++F p+ +++D
       EEA21597.1 193 LLSPMSLVSFTPATSNRD 210
                      567888899999888877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (308 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       808  (0.0450667); expected 358.6 (0.02)
Passed bias filter:                      622  (0.0346924); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2140.75
//
Query:       EEA21598.1  [L=812]
Description: pre-rRNA processing protein Mrd1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-72  239.6   2.4    2.5e-19   68.9   0.0    5.4  5  RRM_1         RNA recognition motif. (a.k.a. RRM, RBD, or RNP
      3e-07   30.2   0.0      0.014   15.2   0.0    4.5  5  RRM_occluded  Occluded RNA-recognition motif
    5.5e-07   29.5   0.1       0.26   11.3   0.0    4.4  5  Nup35_RRM_2   Nup53/35/40-type RNA recognition motif
    4.1e-05   23.6   0.4         12    6.1   0.0    5.2  5  Limkain-b1    Limkain b1
    0.00018   21.1   0.0      0.013   15.1   0.0    3.1  3  RRM_5         RNA recognition motif. (a.k.a. RRM, RBD, or RNP
    0.00066   19.8   0.0         25    5.1   0.0    4.2  4  RRM_7         RNA recognition motif
  ------ inclusion threshold ------
      0.022   14.9   0.0        2.2    8.6   0.0    2.6  2  RRM_2         RNA recognition motif 2


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.5   0.0   1.8e-10   4.7e-07       1      68 [.       6      68 ..       6      70 .. 0.91
   2 !   68.9   0.0   9.6e-23   2.5e-19       1      70 []     288     358 ..     288     358 .. 0.98
   3 !   34.4   0.0   5.5e-12   1.4e-08       1      67 [.     471     532 ..     471     534 .. 0.95
   4 !   45.6   0.0   1.8e-15   4.6e-12       1      69 [.     587     661 ..     587     662 .. 0.94
   5 !   56.9   0.0   5.4e-19   1.4e-15       1      69 [.     692     760 ..     692     761 .. 0.98

  Alignments for each domain:
  == domain 1  score: 29.5 bits;  conditional E-value: 1.8e-10
                EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEE CS
       RRM_1  1 lfVgnLppdvteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkklggre 68
                +fV++Lpp++++e+L ++Fs   p+++  ++++     ++++fV F++ e A++A + +n++ l+ ++
  EEA21598.1  6 VFVSGLPPTLSNEDLGKHFSSRFPVTDSHVIPN-----RRIGFVGFKDAEIAKEAAKYFNKTFLRMSK 68
                8********************888889999996.....*******************99999887665 PP

  == domain 2  score: 68.9 bits;  conditional E-value: 9.6e-23
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrelk 70 
                 lf++nL++d+te +L+++F +fG+i +i +  d +t +skgfa++++ ++++A +A ++l+gk ++gr l+
  EEA21598.1 288 LFLRNLAYDATEADLETIFAPFGKIDEIHVAFDtRTTSSKGFAYIQYVDPSSAIEAYKNLDGKDFQGRLLH 358
                 89*****************************************************************9875 PP

  == domain 3  score: 34.4 bits;  conditional E-value: 5.5e-12
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkklggr 67 
                 + V+n+++ v+  e+++lF++fG+ +++ +++     s  +a+VeF+++++A kA + l  +klg++
  EEA21598.1 471 ILVKNFSYGVKAAEIRKLFEPFGQLTRLLIPP-----SGTIAIVEFAKPDEASKAFKGLAYRKLGDS 532
                 68******************************.....8*********************99999875 PP

  == domain 4  score: 45.6 bits;  conditional E-value: 1.8e-15
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE......TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd......etgkskgfafVeFeskedAekAlealngkklggrel 69 
                 lfV+nL++++t   L+e+F    ++ ++k+ ++          s+gf+f+eF +ke+A++Al+ ++g++l++++l
  EEA21598.1 587 LFVRNLNFTTTSARLSEVFASLDGFLTAKVKTKtdpkrpGETLSMGFGFIEFRTKEQAQAALAVMDGYTLDQHKL 661
                 8******************************9997776666779***************************9987 PP

  == domain 5  score: 56.9 bits;  conditional E-value: 5.4e-19
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkklggrel 69 
                 ++++nLp+ +t+++++ lF+ +G+ +s++++++ +++++gfaf +F s+++Ae+A++al ++ l gr+l
  EEA21598.1 692 IIIKNLPFQATKHDVRSLFGAYGQLRSVRVPKKFDRSARGFAFADFVSSREAENAMDALKNTHLLGRKL 760
                 78**************************************************************99987 PP

>> RRM_occluded  Occluded RNA-recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0      0.33   8.3e+02       8      52 ..      10      53 ..       5      69 .. 0.86
   2 !    6.6   0.0    0.0027         7      36      70 ..     325     359 ..     290     364 .. 0.77
   3 !   15.2   0.0   5.6e-06     0.014       8      55 ..     475     521 ..     469     534 .. 0.88
   4 ?    1.1   0.0      0.14   3.7e+02      42      70 ..     635     663 ..     633     668 .. 0.81
   5 ?   -3.1   0.0       2.9   7.3e+03       8      33 ..     696     720 ..     692     760 .. 0.61

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.33
  RRM_occluded  8 plsDtvnkariralveekegeikkivLvpdheGAivefkdekiag 52
                  +l+ t +++ + ++++++  ++++ ++ p+ +  +v fkd++ia 
    EEA21598.1 10 GLPPTLSNEDLGKHFSSR-FPVTDSHVIPNRRIGFVGFKDAEIAK 53
                  688888999999999999.99*******************99874 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0027
  RRM_occluded  36 pdheGAivefkdekiagkasLaLdgsefegkklrc 70 
                   ++++ A +++ d ++a  a   Ldg++f+g+ l++
    EEA21598.1 325 SSKGFAYIQYVDPSSAIEAYKNLDGKDFQGRLLHI 359
                   4455699*************************997 PP

  == domain 3  score: 15.2 bits;  conditional E-value: 5.6e-06
  RRM_occluded   8 plsDtvnkariralveekegeikkivLvpdheGAivefkdekiagkas 55 
                   ++s  v  a+ir+l+e+  g+++++++ p+   Aivef++   a ka 
    EEA21598.1 475 NFSYGVKAAEIRKLFEPF-GQLTRLLIPPSGTIAIVEFAKPDEASKAF 521
                   66667999**********.**************************996 PP

  == domain 4  score: 1.1 bits;  conditional E-value: 0.14
  RRM_occluded  42 ivefkdekiagkasLaLdgsefegkklrc 70 
                   ++ef+ +++a  a+  +dg++++ +kl +
    EEA21598.1 635 FIEFRTKEQAQAALAVMDGYTLDQHKLVV 663
                   58899888888788889******999976 PP

  == domain 5  score: -3.1 bits;  conditional E-value: 2.9
  RRM_occluded   8 plsDtvnkariralveekegeikkiv 33 
                   +l+ + +k  +r+l+  + g+++ + 
    EEA21598.1 696 NLPFQATKHDVRSLFGAY-GQLRSVR 720
                   666677788888888888.6666554 PP

>> Nup35_RRM_2  Nup53/35/40-type RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.0     0.025        64       2      51 ..       4      54 ..       3      56 .. 0.82
   2 !    8.4   0.0   0.00084       2.2      21      52 ..     306     343 ..     291     344 .. 0.92
   3 !   11.3   0.0    0.0001      0.26      14      52 ..     482     520 ..     468     521 .. 0.86
   4 ?   -1.8   0.0       1.3   3.3e+03      39      53 .]     634     648 ..     631     648 .. 0.90
   5 ?   -0.9   0.0      0.66   1.7e+03      13      52 ..     702     746 ..     700     747 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.025
  Nup35_RRM_2  2 twvaVsGydtelielVle.hFas.fGeIvkhyvpkevsvmyvkfesekdaek 51
                 t v VsG ++ l ++ l  hF s f  ++ h +p ++ + +v f++   a+ 
   EEA21598.1  4 TRVFVSGLPPTLSNEDLGkHFSSrFPVTDSHVIP-NRRIGFVGFKDAEIAKE 54
                 7799*********888888***978888888888.69999999998766665 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.00084
  Nup35_RRM_2  21 FasfGeIvkhyvp......kevsvmyvkfesekdaekA 52 
                  Fa fG+I+++ v       +++ ++y+++ ++ +a  A
   EEA21598.1 306 FAPFGKIDEIHVAfdtrttSSKGFAYIQYVDPSSAIEA 343
                  889*********999****99***********999777 PP

  == domain 3  score: 11.3 bits;  conditional E-value: 0.0001
  Nup35_RRM_2  14 ielVlehFasfGeIvkhyvpkevsvmyvkfesekdaekA 52 
                  +++++  F+ fG+ ++  +p++  +++v+f+++++a kA
   EEA21598.1 482 AAEIRKLFEPFGQLTRLLIPPSGTIAIVEFAKPDEASKA 520
                  4789999******************************99 PP

  == domain 4  score: -1.8 bits;  conditional E-value: 1.3
  Nup35_RRM_2  39 myvkfesekdaekAL 53 
                   +++f+++ +a+ AL
   EEA21598.1 634 GFIEFRTKEQAQAAL 648
                  689*********998 PP

  == domain 5  score: -0.9 bits;  conditional E-value: 0.66
  Nup35_RRM_2  13 lielVlehFasfGeIvkhyvp.....kevsvmyvkfesekdaekA 52 
                  ++ +V+  F  +G+     vp     +++ +++  f s+++ae A
   EEA21598.1 702 TKHDVRSLFGAYGQLRSVRVPkkfdrSARGFAFADFVSSREAENA 746
                  567888889999999998888888898899999999999999988 PP

>> Limkain-b1  Limkain b1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       1.6   4.1e+03      46      76 ..      44      74 ..      40      83 .. 0.78
   2 ?    3.2   0.0     0.037        96      41      73 ..     327     359 ..     322     374 .. 0.82
   3 !    6.1   0.0    0.0045        12      40      61 ..     503     524 ..     480     538 .. 0.81
   4 ?    2.6   0.0     0.056   1.4e+02      45      85 ..     635     675 ..     627     678 .. 0.84
   5 ?    4.4   0.0     0.015        39      43      86 ..     732     775 ..     690     777 .. 0.75

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 1.6
  Limkain-b1 46 lrfanqeaaeralkrleneDvfGnritvsek 76
                + f++ e a+ a k ++       +i+v   
  EEA21598.1 44 VGFKDAEIAKEAAKYFNKTFLRMSKISVEMA 74
                67999999**999999888777777777655 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.037
  Limkain-b1  41 gksavlrfanqeaaeralkrleneDvfGnritv 73 
                 ++ a +++ ++ +a  a k l++ D  G  + +
  EEA21598.1 327 KGFAYIQYVDPSSAIEAYKNLDGKDFQGRLLHI 359
                 5679999******************99986655 PP

  == domain 3  score: 6.1 bits;  conditional E-value: 0.0045
  Limkain-b1  40 sgksavlrfanqeaaeralkrl 61 
                 sg+ a++ fa+++ a++a k l
  EEA21598.1 503 SGTIAIVEFAKPDEASKAFKGL 524
                 8999**************9976 PP

  == domain 4  score: 2.6 bits;  conditional E-value: 0.056
  Limkain-b1  45 vlrfanqeaaeralkrleneDvfGnritvsekprnkevnee 85 
                  + f+ +e a+ al  +++     +++ v+++ +  + +e+
  EEA21598.1 635 FIEFRTKEQAQAALAVMDGYTLDQHKLVVKTSHKGMDAAES 675
                 689*****************999999999999777776665 PP

  == domain 5  score: 4.4 bits;  conditional E-value: 0.015
  Limkain-b1  43 savlrfanqeaaeralkrleneDvfGnritvsekprnkevneee 86 
                  a   f +   ae a+  l n    G ++ +     +++++eee
  EEA21598.1 732 FAFADFVSSREAENAMDALKNTHLLGRKLVLEYASAEAIDAEEE 775
                 46678999999**********************99999999987 PP

>> RRM_5  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0     0.074   1.9e+02      46     111 ..     304     374 ..     284     380 .. 0.71
   2 ?   -3.2   0.0       2.3     6e+03      29      89 ..     471     529 ..     450     534 .. 0.65
   3 !   15.1   0.0   5.2e-06     0.013      39     117 ..     701     784 ..     681     790 .. 0.84

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.074
       RRM_5  46 nlfclYgnvervkflk.....tkketalvqmgdasaveravqHLnnaklfgkrlevalSKqqavsekepfe 111
                  +f+ +g ++ + + +     + k+ a +q  d s++  a + L ++   g+ l++ +   ++  + + +e
  EEA21598.1 304 TIFAPFGKIDEIHVAFdtrttSSKGFAYIQYVDPSSAIEAYKNLDGKDFQGRLLHILPASAKKSYKINDYE 374
                 55666666666665442222257899*************************99999876555533455555 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.3
       RRM_5  29 llVyglepdkvnldklFnlfclYgnvervkflktkketalvqmgdasaveravqHLnnakl 89 
                 +lV ++    v + ++  lf  +g++ r+ +       a+v+ +   ++ +a + L   kl
  EEA21598.1 471 ILVKNFSYG-VKAAEIRKLFEPFGQLTRLLIPP-SGTIAIVEFAKPDEASKAFKGLAYRKL 529
                 566666543.44555666666677777765543.345678888877777777776665555 PP

  == domain 3  score: 15.1 bits;  conditional E-value: 5.2e-06
       RRM_5  39 vnldklFnlfclYgnverv....kflktkketalvqmgdasaveravqHLnnaklfgkrlevalSKqqavse.kepfeleddsp 117
                  + + +  lf+ Yg+++ v    kf ++ ++ a+ +  +++++e a++ L+n++l g++l +     +a+   +e+++ e++++
  EEA21598.1 701 ATKHDVRSLFGAYGQLRSVrvpkKFDRSARGFAFADFVSSREAENAMDALKNTHLLGRKLVLEYASAEAIDAeEEIRNIEKKTG 784
                 57788999********9884466688899********************************99988888865477777777665 PP

>> RRM_7  RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.0     0.019        49       3      24 ..       5      26 ..       3      34 .. 0.87
   2 !    5.1   0.0    0.0096        25       2      57 ..     286     334 ..     285     351 .. 0.69
   3 ?   -3.4   0.0       4.2   1.1e+04      46      67 ..     627     648 ..     603     671 .. 0.61
   4 ?    5.0   0.0      0.01        27       3      37 ..     691     727 ..     689     754 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.019
       RRM_7  3 kvFvGGlPiDiteeelkatfke 24
                +vFv GlP+ +++e+l + f++
  EEA21598.1  5 RVFVSGLPPTLSNEDLGKHFSS 26
                8***************999975 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0096
       RRM_7   2 rkvFvGGlPiDiteeelkatfkefgkvlvdwPkkaeskkkaaenskaakgyvflvf 57 
                  ++F+  l  D te++l++ f  fgk+        e + ++ + +++ kg++++ +
  EEA21598.1 286 GRLFLRNLAYDATEADLETIFAPFGKID-------EIHVAFDTRTTSSKGFAYIQY 334
                 578999999****************863.......222222222334456666555 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 4.2
       RRM_7  46 skaakgyvflvfedeksvkaLl 67 
                 ++   g+ f+ f +++  +a l
  EEA21598.1 627 ETLSMGFGFIEFRTKEQAQAAL 648
                 3345688888887665555433 PP

  == domain 4  score: 5.0 bits;  conditional E-value: 0.01
       RRM_7   3 kvFvGGlPiDiteeelkatfkefgkvl.vdwPkk.ae 37 
                 k+ +  lP   t++++ + f+++g+++ v  Pkk  +
  EEA21598.1 691 KIIIKNLPFQATKHDVRSLFGAYGQLRsVRVPKKfDR 727
                 899999******************9854888888433 PP

>> RRM_2  RNA recognition motif 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.0   0.00084       2.2      28      70 ..     310     352 ..     294     356 .. 0.90
   2 ?    3.3   0.0     0.036        93       1      57 [.     689     742 ..     689     755 .. 0.74

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00084
       RRM_2  28 gtydflylpidfknkcnvgyafinlvepkkivafqkafngkkw 70 
                 g+ d + +  d +     g+a+i+ v+p + +  +k   gk +
  EEA21598.1 310 GKIDEIHVAFDTRTTSSKGFAYIQYVDPSSAIEAYKNLDGKDF 352
                 66777888899999999***********************986 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.036
       RRM_2   1 rttlliknipnkytkkmllaaideknkgtydflylpidfknkcnvgyafinlvepkk 57 
                 rt ++ikn+p + tk+ +++     + g+   + +p  f  +   g+af ++v+ ++
  EEA21598.1 689 RTKIIIKNLPFQATKHDVRSLFG--AYGQLRSVRVPKKFD-RSARGFAFADFVSSRE 742
                 899*********99998888764..356666677777774.5567888888887665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (812 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       991  (0.0552736); expected 358.6 (0.02)
Passed bias filter:                      530  (0.029561); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.73u 0.34s 00:00:01.07 Elapsed: 00:00:00.51
# Mc/sec: 4823.41
//
Query:       EEA21599.1  [L=823]
Description: transcription factor AbaA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.9e-27   93.5   0.0    1.5e-26   92.2   0.0    1.7  1  TEA       TEA/ATTS domain


Domain annotation for each model (and alignments):
>> TEA  TEA/ATTS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.2   0.0   8.4e-31   1.5e-26       2      66 ..     135     199 ..     134     201 .. 0.97

  Alignments for each domain:
  == domain 1  score: 92.2 bits;  conditional E-value: 8.4e-31
         TEA   2 ekvWppeledafleallliPpmgrrklklegklhgRnelIseyIlkktgkertrKQvsShiQvlk 66 
                 e vW++ ledaf +al++ Ppmgrrk + +gk +gRnelI+eyI+k tgk+rtrKQvsSh+Qvl 
  EEA21599.1 135 EPVWSDALEDAFQQALEANPPMGRRKWSERGKSYGRNELIAEYIYKLTGKRRTRKQVSSHLQVLD 199
                 78*************************************************************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (823 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       642  (0.0358079); expected 358.6 (0.02)
Passed bias filter:                      419  (0.02337); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.74u 0.30s 00:00:01.04 Elapsed: 00:00:00.50
# Mc/sec: 4923.49
//
Query:       EEA21600.1  [L=320]
Description: D-xylose reductase (Xyl1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.6e-43  148.3   0.0    3.9e-43  147.7   0.0    1.3  1  Aldo_ket_red  Aldo/keto reductase family
  ------ inclusion threshold ------
       0.15   11.7   0.0       0.23   11.1   0.0    1.2  1  DUF2380       Predicted lipoprotein of unknown function (DUF2


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  147.7   0.0   4.4e-47   3.9e-43       2     292 ..      17     300 ..      16     302 .. 0.89

  Alignments for each domain:
  == domain 1  score: 147.7 bits;  conditional E-value: 4.4e-47
                   EEEE-SSS-ST.TS-HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHH.HHHHHHH-TTTGGG-EEEEEE--SSSTTSSSS-HHHHHHHHHHHHHHH CS
  Aldo_ket_red   2 lglGtwqlgskeeiskeealellrraleaGinffDtAevYgkgqseel.lGealkksrkkreeviiatKvdlrdaeiksglskeniresleeslkrL 97 
                   +g+G+w++++      e+ ++ + +a++aG+++fD A  Yg+ +     +++alk+  +kree++i++K+      ++  +  + ++   +++l+ L
    EEA21600.1  17 VGFGLWKVNN------ETCADQVYAAIKAGYRLFDGACDYGNEKEVGQgIARALKDGLVKREELFIVSKL------WNTFHDGDKVEPIARKQLEDL 101
                   6899997776......677777888999************5555555556668888**************......9999***************** PP

                   T-S-EEEEEE-S--TTS-........................HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHHHHTTT--EEEEE-B-BTT-HHH CS
  Aldo_ket_red  98 gtdyvDllllHrpdpslp.......................sieevldaleelvkeGkiraiGvSnfsveqlekakkkkkvkivavqveynllrele 171
                   g +y+Dl+l+H p                             i e+++a+e lv++ ++r+iGvSnfs++ +  +++++ ++++++q+e++++  l+
    EEA21600.1 102 GIEYFDLYLIHFPVALKWvdpaeryppswtgadgkitfsnaTIQETWQAMESLVDKKLARSIGVSNFSAQLIMDLLRHARIRPATLQIEHHPY--LQ 196
                   ***********9976544589999*********************************************************************..** PP

                   HTTHHHHHHHTT-EEEEBSTTGGGTTGTTTSS---SSSCCC-------TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTSTT-SEEEE--SSHH CS
  Aldo_ket_red 172 eegllelckkkgvpliaysplggGlltgkyqseedkedkeprkdlkrdertsknldaaeelselakehgvslaqlalryalsqpavgivipgasnie 268
                   +++l+++++++g+ + ays +g  ++   + + ++ +   + +          +l   + +++ a+++g+s+aq+ lr+a+  ++++ vip++  ++
    EEA21600.1 197 QQQLVKYVQNEGITITAYSSFGPLSFI--ELDMKRAH---NTP----------TLFEHNVIKSAAEKYGKSPAQILLRWAT--QRNIAVIPKSNDPA 276
                   *********************975555..33333333...333..........34667899********************..9************* PP

                   HHHHHHGGGG----HHHHHHHHHH CS
  Aldo_ket_red 269 qlednldalelklseeevaeldel 292
                   +l +nld+  ++l e e+++++ l
    EEA21600.1 277 RLAQNLDVTGWNLEEAEIEAINGL 300
                   ********************9976 PP

>> DUF2380  Predicted lipoprotein of unknown function (DUF2380)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   2.6e-05      0.23      80     125 ..     167     214 ..     123     221 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 2.6e-05
     DUF2380  80 rwkkre..kllpalrrleagrwvkhhlfPqaeelaewFerkgikihdy 125
                 +++ +    ll+++r ++a+  + hh + q+++l ++ +++gi i  y
  EEA21600.1 167 NFSAQLimDLLRHARIRPATLQIEHHPYLQQQQLVKYVQNEGITITAY 214
                 4444433355666777778889***********************988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (320 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       531  (0.0296168); expected 358.6 (0.02)
Passed bias filter:                      514  (0.0286686); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.48
# Mc/sec: 1997.09
//
Query:       EEA21601.1  [L=205]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (205 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       412  (0.0229795); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.41u 0.28s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1494.57
//
Query:       EEA21602.1  [L=348]
Description: protein phosphatase PP1 regulatory subunit Sds22, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.5e-34  116.3  37.5    5.3e-09   36.2   5.9    7.1  9  LRR_4     Leucine Rich repeats (2 copies)
      2e-20   72.3  35.8    7.1e-06   25.7   5.2    6.4  7  LRR_8     Leucine rich repeat
    3.3e-14   52.8  17.6    5.4e-06   26.0   2.7    4.1  4  LRR_9     Leucine-rich repeat
    9.2e-05   22.5  27.1        6.2    7.8   0.3    8.7  8  LRR_1     Leucine Rich Repeat
     0.0016   18.3  26.4        2.8    8.2   0.1    7.7  7  LRR_6     Leucine Rich repeat


Domain annotation for each model (and alignments):
>> LRR_4  Leucine Rich repeats (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.2   1.2e-05     0.043       3      43 ..      64      99 ..      63     100 .. 0.84
   2 !   21.2   1.1   7.6e-08   0.00027       1      42 [.      81     122 ..      81     125 .. 0.86
   3 !   18.8   3.7   4.4e-07    0.0016       3      41 ..     106     143 ..     104     146 .. 0.87
   4 !   17.3   1.3   1.3e-06    0.0046       2      43 ..     127     167 ..     126     169 .. 0.91
   5 !   20.5   0.1   1.3e-07   0.00046       1      44 []     148     190 ..     148     190 .. 0.91
   6 !   26.8   0.7   1.3e-09   4.7e-06       2      43 ..     171     211 ..     170     213 .. 0.88
   7 !   36.2   5.9   1.5e-12   5.3e-09       2      44 .]     215     256 ..     214     256 .. 0.96
   8 !   30.3   0.1     1e-10   3.7e-07       1      40 [.     258     296 ..     258     302 .. 0.90
   9 ?    3.2   0.0     0.036   1.3e+02       9      36 ..     288     318 ..     287     342 .. 0.72

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 1.2e-05
                --EEE--SS---E-S-HHH-TT--EEE-.-S-----GGGGX CS
       LRR_4  3 LevLdLsnNqltdiplleklpnLkeLdLsgNnlitdldeLk 43
                L +L +sn  +t + l + +++L+ L L + n+i+++ eL+
  EEA21602.1 64 LVHLRISN--ITALKLER-FTKLERLCL-RQNQISRI-ELP 99
                67999999..99999999.*******88.66699999.565 PP

  == domain 2  score: 21.2 bits;  conditional E-value: 7.6e-08
                 SS--EEE--SS---E-S-HHH-TT.--EEE-.-S-----GGGG CS
       LRR_4   1 pnLevLdLsnNqltdiplleklpn.LkeLdLsgNnlitdldeL 42 
                 ++Le L+L++Nq++ i+l++ l   LkeLdL +N li+ + +L
  EEA21602.1  81 TKLERLCLRQNQISRIELPSTLGAtLKELDLYDN-LISHVKGL 122
                 79****************9986667******666.99888766 PP

  == domain 3  score: 18.8 bits;  conditional E-value: 4.4e-07
                 --EEE--SS---E-S-HHH-TT--EEE-.-S-----GGG CS
       LRR_4   3 LevLdLsnNqltdiplleklpnLkeLdLsgNnlitdlde 41 
                 L++LdL +N ++ + +l  l nL+ LdLs+N +i+ + +
  EEA21602.1 106 LKELDLYDNLISHVKGLDDLVNLTLLDLSFN-KIKHIKN 143
                 9*********999999999*********888.8877755 PP

  == domain 4  score: 17.3 bits;  conditional E-value: 1.3e-06
                 S--EEE--SS---E-S-HHH-TT--EEE-.-S-----GGGGX CS
       LRR_4   2 nLevLdLsnNqltdiplleklpnLkeLdLsgNnlitdldeLk 43 
                 nL+ LdLs N+++ i + + l++L+ +   +N +i+++++L+
  EEA21602.1 127 NLTLLDLSFNKIKHIKNVSHLTKLTDIFFVQN-RISTIEGLE 167
                 9************9999888*******99899.999999986 PP

  == domain 5  score: 20.5 bits;  conditional E-value: 1.3e-07
                 SS--EEE--SS---E-S-HHH-TT--EEE-.-S-----GGGGXX CS
       LRR_4   1 pnLevLdLsnNqltdiplleklpnLkeLdLsgNnlitdldeLkn 44 
                 ++L+ + + +N++++i++le l +L+ L L g n+i+ + +L n
  EEA21602.1 148 TKLTDIFFVQNRISTIEGLEELVHLRNLEL-GANRIREIQGLDN 190
                 689999999*********************.766*****99976 PP

  == domain 6  score: 26.8 bits;  conditional E-value: 1.3e-09
                 S--EEE--SS---E-S-HHH-TT--EEE-.-S-----GGGGX CS
       LRR_4   2 nLevLdLsnNqltdiplleklpnLkeLdLsgNnlitdldeLk 43 
                 +L++L L+ N++++i++l +l+ L++L+L g n+it   +L+
  EEA21602.1 171 HLRNLELGANRIREIQGLDNLKALEQLWL-GKNKITEMKNLS 211
                 79******88*******************.655999887776 PP

  == domain 7  score: 36.2 bits;  conditional E-value: 1.5e-12
                 S--EEE--SS---E-S-HHH-TT--EEE-.-S-----GGGGXX CS
       LRR_4   2 nLevLdLsnNqltdiplleklpnLkeLdLsgNnlitdldeLkn 44 
                 nL++L++++N+lt+i +l+ lpnL+eL++s+N  +tdl++L+n
  EEA21602.1 215 NLKILSIQSNRLTSITGLNELPNLEELYISHN-ALTDLSGLEN 256
                 9****************************999.999***9986 PP

  == domain 8  score: 30.3 bits;  conditional E-value: 1e-10
                 SS--EEE--SS---E-S-HHH-TT--EEE-.-S-----GG CS
       LRR_4   1 pnLevLdLsnNqltdiplleklpnLkeLdLsgNnlitdld 40 
                 +nL+vLd+snN++t+++++++l+ L+e++ s+N  +++++
  EEA21602.1 258 KNLRVLDFSNNKVTKLEGISQLTELEEVWASSN-GLSSFE 296
                 7*****************999*********888.777765 PP

  == domain 9  score: 3.2 bits;  conditional E-value: 0.036
                 -SS---E-S-....HHH-TT--EEE-.-S--- CS
       LRR_4   9 snNqltdipl....leklpnLkeLdLsgNnli 36 
                 s+N l++++     l+  ++L++++  gN ++
  EEA21602.1 288 SSNGLSSFEEvereLSDKKKLETVYFEGN-PL 318
                 56777877775544335688999998888.33 PP

>> LRR_8  Leucine rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   0.2   0.00066       2.4       8      41 ..      64      97 ..      60     100 .. 0.72
   2 !   25.7   5.2     2e-09   7.1e-06       2      61 .]      82     138 ..      81     138 .. 0.94
   3 !   15.7   0.2   2.7e-06    0.0095      22      61 .]     145     182 ..     140     182 .. 0.94
   4 !   14.7   3.1   5.3e-06     0.019      22      61 .]     189     226 ..     184     226 .. 0.94
   5 !   25.0   4.4   3.2e-09   1.1e-05      20      61 .]     209     248 ..     205     248 .. 0.92
   6 !   15.2   0.6   3.9e-06     0.014      22      60 ..     255     291 ..     249     292 .. 0.87
   7 ?   -3.9   0.0       3.4   1.2e+04      46      61 .]     303     318 ..     299     319 .. 0.63

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00066
                -TTS--SEE-TTSSTT-TT--EEE--SS---GGG CS
       LRR_8  8 LsnNrltslddeaFkglsnLkvLdLsnNllttls 41
                L + r++++     +++++L+ L L++N++++++
  EEA21602.1 64 LVHLRISNITALKLERFTKLERLCLRQNQISRIE 97
                4555555555555555669***********9996 PP

  == domain 2  score: 25.7 bits;  conditional E-value: 2e-09
                 T-SEEE-TTS--SEE-TTSSTT-TT--EEE--SS---GGGGGGGTT--S-.EEE--SS-- CS
       LRR_8   2 nLtsLdLsnNrltslddeaFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 
                 +L++L L+ N+++ ++  +  g   Lk+LdL +Nl++++  + +++L +L+ LdLs N++
  EEA21602.1  82 KLERLCLRQNQISRIELPSTLG-ATLKELDLYDNLISHV--KGLDDLVNLTLLDLSFNKI 138
                 799*************988886.9***************..6****************97 PP

  == domain 3  score: 15.7 bits;  conditional E-value: 2.7e-06
                 TT-TT--EEE--SS---GGGGGGGTT--S-.EEE--SS-- CS
       LRR_8  22 kglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 
                 ++l++L+ +   +N+++t++   ++ L +Lr L L  Nr+
  EEA21602.1 145 SHLTKLTDIFFVQNRISTIE--GLEELVHLRNLELGANRI 182
                 789****************6..****************97 PP

  == domain 4  score: 14.7 bits;  conditional E-value: 5.3e-06
                 TT-TT--EEE--SS---GGGGGGGTT--S-.EEE--SS-- CS
       LRR_8  22 kglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 
                  +l++L+ L L+ N++t +  + +s+L++L+ L +++NrL
  EEA21602.1 189 DNLKALEQLWLGKNKITEM--KNLSSLSNLKILSIQSNRL 226
                 589****************..5****************98 PP

  == domain 5  score: 25.0 bits;  conditional E-value: 3.2e-09
                 SSTT-TT--EEE--SS---GGGGGGGTT--S-.EEE--SS-- CS
       LRR_8  20 aFkglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNrL 61 
                   ++lsnLk+L++ +N+lt++    +  Lp+L++L++s+N L
  EEA21602.1 209 NLSSLSNLKILSIQSNRLTSIT--GLNELPNLEELYISHNAL 248
                 5689*****************5..****************87 PP

  == domain 6  score: 15.2 bits;  conditional E-value: 3.9e-06
                 TT-TT--EEE--SS---GGGGGGGTT--S-.EEE--SS- CS
       LRR_8  22 kglsnLkvLdLsnNllttlspgafsgLpsLrsLdLsgNr 60 
                 ++++nL+vLd snN+ t l+   +s+L+ L++   s+N 
  EEA21602.1 255 ENNKNLRVLDFSNNKVTKLE--GISQLTELEEVWASSNG 291
                 689****************6..99999999988777776 PP

  == domain 7  score: -3.9 bits;  conditional E-value: 3.4
                 TT--S-.EEE--SS-- CS
       LRR_8  46 sgLpsLrsLdLsgNrL 61 
                 s+ ++L+  + +gN+L
  EEA21602.1 303 SDKKKLETVYFEGNPL 318
                 5556677767677765 PP

>> LRR_9  Leucine-rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.1   0.8     0.002       7.1      56     115 ..      76     131 ..      57     132 .. 0.68
   2 !   23.8   3.1   7.3e-09   2.6e-05      23     115 ..     108     197 ..     107     199 .. 0.86
   3 !   26.0   2.7   1.5e-09   5.4e-06      49     126 ..     199     271 ..     195     274 .. 0.85
   4 !   15.2   0.1   3.1e-06     0.011      50     151 ..     244     346 ..     243     348 .] 0.88

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.002
       LRR_9  56 kldgfPllkrlktlllnnnrivriaegleevl.PnleelvltnnelqeladldPlaslkkl 115
                 kl+    + +l+ l l +n+i ri+  l  +l  +l+el l +n + ++  ld l++l  l
  EEA21602.1  76 KLER---FTKLERLCLRQNQISRIE--LPSTLgATLKELDLYDNLISHVKGLDDLVNLTLL 131
                 3344...455666789999999995..5455425788999999999999999999888655 PP

  == domain 2  score: 23.8 bits;  conditional E-value: 7.3e-09
       LRR_9  23 eldlrgykipvienlGatldqfdtidlsdndirkldgfPllkrlktlllnnnrivriaegleevlPnleelvltnnelqeladldPlaslkkl 115
                 eldl  + i+ ++ l   l  +  +dls n+i+++ ++ +l +l  +++ +nri  i eglee + +l++l l  n+++e+  ld l  l++l
  EEA21602.1 108 ELDLYDNLISHVKGLDD-LVNLTLLDLSFNKIKHIKNVSHLTKLTDIFFVQNRISTI-EGLEELV-HLRNLELGANRIREIQGLDNLKALEQL 197
                 77777777777777754.5567789*****************************988.7999865.8******************99999887 PP

  == domain 3  score: 26.0 bits;  conditional E-value: 1.5e-09
       LRR_9  49 lsdndirkldgfPllkrlktlllnnnrivriaegleevlPnleelvltnnelqeladldPlaslkklellsllknpvt 126
                 l  n+i ++ ++  l  lk+l++++nr++ i+ gl+e lPnleel +++n l++l+    l + k+l++l + +n vt
  EEA21602.1 199 LGKNKITEMKNLSSLSNLKILSIQSNRLTSIT-GLNE-LPNLEELYISHNALTDLSG---LENNKNLRVLDFSNNKVT 271
                 5689**************************96.7876.9***********9998888...556677777777777776 PP

  == domain 4  score: 15.2 bits;  conditional E-value: 3.1e-06
       LRR_9  50 sdndirkldgfPllkrlktlllnnnrivriaegleevlPnleelvltnnelqeladld.Plaslkklellsllknpvtnkk..eyrlyviyklkqlrll 145
                 s n + +l g+   k l++l ++nn+++++ eg+++ l +lee+  ++n l ++ +++  l + kkle++ +  np+  k+   yr+ +   l+q++ +
  EEA21602.1 244 SHNALTDLSGLENNKNLRVLDFSNNKVTKL-EGISQ-LTELEEVWASSNGLSSFEEVErELSDKKKLETVYFEGNPLQLKSpaLYRNKIRLALPQIKQI 340
                 789999**********************98.68876.789*****************8459999************98875226************999 PP

       LRR_9 146 dfrkvk 151
                 d   v+
  EEA21602.1 341 DATYVR 346
                 976665 PP

>> LRR_1  Leucine Rich Repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.2     0.014        49       1      18 [.      82      99 ..      82     103 .. 0.84
   2 ?    3.3   0.1      0.05   1.8e+02       2      12 ..     106     116 ..     105     124 .. 0.83
   3 ?    5.0   0.3     0.014        51       1      14 [.     127     140 ..     127     152 .. 0.79
   4 ?   -0.5   0.2      0.89   3.2e+03       2      13 ..     172     185 ..     171     213 .. 0.61
   5 ?    3.9   0.3     0.032   1.1e+02       1      15 [.     215     229 ..     215     233 .. 0.87
   6 !    7.8   0.3    0.0017       6.2       1      15 [.     237     251 ..     237     257 .. 0.84
   7 !    6.1   0.1     0.006        22       1      12 [.     259     270 ..     259     296 .. 0.86
   8 ?    4.5   0.0     0.021        76       1      19 [.     307     324 ..     307     328 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.014
       LRR_1  1 nLrhLdLsnnpllglppn 18
                +L++L L++n++++++ +
  EEA21602.1 82 KLERLCLRQNQISRIELP 99
                7**********9877665 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.05
       LRR_1   2 LrhLdLsnnpl 12 
                 L++LdL +n +
  EEA21602.1 106 LKELDLYDNLI 116
                 9*****99987 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.014
       LRR_1   1 nLrhLdLsnnpllg 14 
                 nL+ LdLs n + +
  EEA21602.1 127 NLTLLDLSFNKIKH 140
                 89********9833 PP

  == domain 4  score: -0.5 bits;  conditional E-value: 0.89
       LRR_1   2 LrhLdLsnnpl..l 13 
                 Lr L L+ n++  +
  EEA21602.1 172 LRNLELGANRIreI 185
                 66666666655221 PP

  == domain 5  score: 3.9 bits;  conditional E-value: 0.032
       LRR_1   1 nLrhLdLsnnpllgl 15 
                 nL+ L + +n+l+++
  EEA21602.1 215 NLKILSIQSNRLTSI 229
                 8**********9654 PP

  == domain 6  score: 7.8 bits;  conditional E-value: 0.0017
       LRR_1   1 nLrhLdLsnnpllgl 15 
                 nL++L++s+n l++l
  EEA21602.1 237 NLEELYISHNALTDL 251
                 8*********99655 PP

  == domain 7  score: 6.1 bits;  conditional E-value: 0.006
       LRR_1   1 nLrhLdLsnnpl 12 
                 nLr+Ld snn  
  EEA21602.1 259 NLRVLDFSNNKV 270
                 8*********85 PP

  == domain 8  score: 4.5 bits;  conditional E-value: 0.021
       LRR_1   1 nLrhLdLsnnpllglppns 19 
                 +L++ + ++npl +l +++
  EEA21602.1 307 KLETVYFEGNPL-QLKSPA 324
                 79**********.887776 PP

>> LRR_6  Leucine Rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.1      0.67   2.4e+03       3      16 ..      81      94 ..      81      94 .. 0.87
   2 ?    3.5   0.1     0.026        92       4      15 ..     105     116 ..     104     118 .. 0.89
   3 !    6.8   0.5    0.0022       7.8       4      15 ..     127     138 ..     125     139 .. 0.90
   4 ?    0.5   0.0      0.24   8.7e+02       4      15 ..     171     182 ..     168     183 .. 0.88
   5 ?    4.1   0.5     0.017        60       2      16 ..     213     227 ..     212     228 .. 0.88
   6 !    8.2   0.1   0.00079       2.8       3      17 ..     236     250 ..     234     254 .. 0.90
   7 !    7.6   0.8    0.0012       4.3       1      16 [.     256     271 ..     256     273 .. 0.92

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.67
       LRR_6  3 thLteLdLsgNdIg 16
                t+L+ L L+ N+I+
  EEA21602.1 81 TKLERLCLRQNQIS 94
                6899999*****96 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.026
       LRR_6   4 hLteLdLsgNdI 15 
                 +L+eLdL +N I
  EEA21602.1 105 TLKELDLYDNLI 116
                 8******99988 PP

  == domain 3  score: 6.8 bits;  conditional E-value: 0.0022
       LRR_6   4 hLteLdLsgNdI 15 
                 +Lt LdLs+N+I
  EEA21602.1 127 NLTLLDLSFNKI 138
                 7999*******9 PP

  == domain 4  score: 0.5 bits;  conditional E-value: 0.24
       LRR_6   4 hLteLdLsgNdI 15 
                 hL+ L+L  N I
  EEA21602.1 171 HLRNLELGANRI 182
                 9******99988 PP

  == domain 5  score: 4.1 bits;  conditional E-value: 0.017
       LRR_6   2 nthLteLdLsgNdIg 16 
                  ++L+ L++++N ++
  EEA21602.1 213 LSNLKILSIQSNRLT 227
                 589*********997 PP

  == domain 6  score: 8.2 bits;  conditional E-value: 0.00079
       LRR_6   3 thLteLdLsgNdIgD 17 
                 ++L+eL +s+N ++D
  EEA21602.1 236 PNLEELYISHNALTD 250
                 79************9 PP

  == domain 7  score: 7.6 bits;  conditional E-value: 0.0012
       LRR_6   1 snthLteLdLsgNdIg 16 
                 +n +L+ Ld s N+++
  EEA21602.1 256 NNKNLRVLDFSNNKVT 271
                 699**********987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (348 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       384  (0.0214178); expected 358.6 (0.02)
Passed bias filter:                      234  (0.0130515); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.48u 0.23s 00:00:00.71 Elapsed: 00:00:00.40
# Mc/sec: 2612.44
//
Query:       EEA21603.1  [L=534]
Description: general stress response phosphoprotein phosphatase Psr1/2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-54  182.8   0.1    4.8e-54  182.4   0.1    1.2  1  NIF       NLI interacting factor-like phosphatase


Domain annotation for each model (and alignments):
>> NIF  NLI interacting factor-like phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  182.4   0.1   2.7e-58   4.8e-54       1     155 [.     365     526 ..     365     527 .. 0.93

  Alignments for each domain:
  == domain 1  score: 182.4 bits;  conditional E-value: 2.7e-58
         NIF   1 ktLVLDLDetLvhskleksk....klkve..gekvevsvlkRpgldefLkelsklyevvifTasseeyaeavidildpekkllshrlyrescvkkkgey 93 
                 k+LVLDLDetLvhs+++  +    +++ve  g+ ++++v+kRpg+d+f+k++ +lyevv+fTas ++y ++ +d+ld ++  ++hrl+r+sc   +g+y
  EEA21603.1 365 KCLVLDLDETLVHSSFKVLEradfTIPVEieGQWHNIYVIKRPGVDQFMKRVGELYEVVVFTASVSKYGDPLLDQLDIHNV-VHHRLFRDSCYNHQGNY 462
                 79*************9555348775555565889*********************************************96.**********766**** PP

         NIF  94 vKdLsllgrdlsrvvivDdspdsfelqpengipiksffsdkkDneLlkllpllkela..kvddv 155
                 vKdLs +grdl++++i+D+sp+s+ ++p+++ipi+s+fsd +DneLl+l+p+l++la  +v+dv
  EEA21603.1 463 VKDLSQVGRDLRETIIIDNSPTSYIFHPQHAIPISSWFSDAHDNELLDLIPVLEDLAgaQVQDV 526
                 ********************************************************98888998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (534 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1877  (0.104691); expected 358.6 (0.02)
Passed bias filter:                      671  (0.0374254); expected 358.6 (0.02)
Passed Vit filter:                       111  (0.00619109); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.91u 0.32s 00:00:01.23 Elapsed: 00:00:00.50
# Mc/sec: 3222.37
//
Query:       EEA21604.1  [L=816]
Description: peroxisomal ABC transporter (PXA1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.6e-88  295.5   1.2    4.5e-88  295.1   0.2    1.6  2  ABC_membrane_2  ABC transporter transmembrane region 2
    6.1e-15   55.9   0.0    1.1e-14   55.1   0.0    1.5  1  ABC_tran        ABC transporter
     0.0036   17.2   0.0     0.0073   16.1   0.0    1.5  1  AAA_21          AAA domain, putative AbiEii toxin, Type IV TA
  ------ inclusion threshold ------
       0.01   16.4   2.9       0.18   12.3   2.9    2.3  1  AAA_23          AAA domain
      0.039   14.4   0.0       0.12   12.8   0.0    1.8  2  AAA             ATPase family associated with various cellula
        0.1   12.4   0.0       0.38   10.5   0.0    1.9  2  AAA_29          P-loop containing region of AAA domain
        0.1   12.0   0.0       0.21   10.9   0.0    1.4  1  Mg_chelatase    Magnesium chelatase, subunit ChlI
       0.11   12.3   0.0       0.26   11.0   0.0    1.6  1  RuvB_N          Holliday junction DNA helicase RuvB P-loop do
       0.11   12.2   0.0       0.27   10.9   0.0    1.6  1  IstB_IS21       IstB-like ATP binding protein
       0.14   12.4   0.1       0.59   10.4   0.0    2.0  2  AAA_22          AAA domain


Domain annotation for each model (and alignments):
>> ABC_membrane_2  ABC transporter transmembrane region 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  295.1   0.2   2.5e-91   4.5e-88       1     269 []     155     425 ..     155     425 .. 0.99
   2 ?   -2.7   0.0       1.7   3.1e+03      64      83 ..     719     738 ..     716     740 .. 0.86

  Alignments for each domain:
  == domain 1  score: 295.1 bits;  conditional E-value: 2.5e-91
  ABC_membrane_2   1 LlkilipklkskeallllvlllllvlrtllsvlvaqldgklvkalvaknvraFvlsllkfallavpasfvnsalkYltqkLalafRkrLtkhlls 95 
                     L++i+ p+++ske++ll+ ++++l+lrt+ls+lva+ldg++v+ lva++ raF++ llk++ +  +as++n+++++l++k+++afR+rLt+++++
      EEA21604.1 155 LMSIMNPRWHSKETGLLMSHAVFLLLRTYLSLLVARLDGEIVRDLVAGKGRAFLWGLLKWCSIGTFASYTNAMIQFLQSKISIAFRTRLTRYIHD 249
                     678899***************************************************************************************** PP

  ABC_membrane_2  96 eYlknr.tyYkvsnlde.ridnpDqritqDvekFtsslssLlsglvkpildvilftfiLwslsgtlgllllllyvllatvilriigpplgklvae 188
                      Yl+++ +yYk+ nld+   + +Dq itqD++ F++s++ L+s+l kp +d+i+ft++L++ +g+l+l+ +l+ ++ ++++lr+++pp+gkl+a 
      EEA21604.1 250 LYLNENaNYYKLTNLDGaVGQGADQFITQDLTLFCASAAALTSSLGKPAVDLIFFTYQLYRGLGPLALTGILSGYFTTATVLRRLSPPFGKLKAV 344
                     ***99889*********55699************************************************************************* PP

  ABC_membrane_2 189 eeklegefRylhsrlitnaEeIAFyrGeevEkkqlqrrfkslidnlrrilsrrlrlgiieafvlkYlasilgyvlvalpif 269
                     e k+eg+fR lhsrl +naEeIAFy+G+ +Ek  l+++fk+l ++++ i+s ++r++++e+++lkY++s++gy++ ++p+f
      EEA21604.1 345 EGKREGDFRGLHSRLLANAEEIAFYGGADIEKVFLTKSFKDLQRWMQGIYSLKIRYNMLEDMILKYVWSAFGYLMTSIPVF 425
                     *******************************************************************************98 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 1.7
  ABC_membrane_2  64 avpasfvnsalkYltqkLal 83 
                     ++ +s+++s++kY+t +L l
      EEA21604.1 719 LITISTRASLKKYHTFQLTL 738
                     68899**********99987 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.1   0.0   6.3e-18   1.1e-14       2     136 ..     553     697 ..     552     698 .. 0.88

  Alignments for each domain:
  == domain 1  score: 55.1 bits;  conditional E-value: 6.3e-18
                 EEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH..............HHHTCHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..............xxxxxxx RF
    ABC_tran   2 knvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren..............esdeeie 86 
                 + +s+ ++ ge + i G+nG GKS++++++agl     G +        ++++ +    i +lpq p l  ++ +r++                d+e++
  EEA21604.1 553 ESLSFIVHSGEHLLICGPNGVGKSSIARIVAGLWPVYRGLV--------SRPRDFGMDGIMFLPQRPYLSVGT-LRDQviyphteidmresgRTDAELS 642
                 5789*************************************........446778888999999998888888.88888888888888888999999** PP

                 HHHHHSTTGGTTCBGESTTS.....GGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 xxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  87 kalsklglkelkdtvvkssp.....ssLSgGqkqrvalarallkkpkllllDEpt 136
                 ++l+++ l +l+ +  + +        LSgG+kqr+a ar+l  +p+  ++DE t
  EEA21604.1 643 RILEEVHLGYLPSREGGWNCrkewkDVLSGGEKQRMAFARLLYHEPRYAFIDEGT 697
                 **********88887655555567799**************************88 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0   4.1e-06    0.0073       3      98 ..     566     661 ..     565     671 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 4.1e-06
      AAA_21   3 vliGpNgsGKSnLLdaldllarldrdvegltdelsggggirkipslldlydpeipfefeieeflsqgvryryglrlersqv....eeklssvetllesg 97 
                 ++ GpNg+GKS++ ++  +l   ++  +gl + ++++g+ +++   +++y   +  + +++  + ++++ r + r + +      e +l+ ++++++ +
  EEA21604.1 566 LICGPNGVGKSSIARIVAGL---WPVYRGLVSRPRDFGMDGIMFLPQRPYLSVGTLRDQVI-YPHTEIDMRESGRTDAELSrileEVHLGYLPSREGGW 660
                 699*****************...99999999999999999999999999999998888888.7777777776666666665556555555555555555 PP

      AAA_21  98 l 98 
                  
  EEA21604.1 661 N 661
                 5 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   2.9    0.0001      0.18      22     186 ..     565     790 ..     552     795 .. 0.47

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.0001
      AAA_23  22 tlItGpNGaGKTTildAiklaLygetprlsrks.................grgfeksdveiese..................gkvkayveltfenkdgr 85 
                  lI+GpNG GK++i + i  +L+   ++l ++                  +            +                  g ++a +++ +e  + +
  EEA21604.1 565 LLICGPNGVGKSSIAR-IVAGLWPVYRGLVSRPrdfgmdgimflpqrpylSV-----------GtlrdqviyphteidmresGRTDAELSRILEEVHLG 651
                 69************98.55677777777766655555554444444444311...........122222222222222322233333333333333333 PP

      AAA_23  86 y......trsiererelskkkgkttkkaklelleideleqfise............llgskki..........ilnlilflgqer.............. 142
                 y        +++ e +   + g+++++a  +ll+++ +  fi+e            l++++k+          +       +  +              
  EEA21604.1 652 YlpsregGWNCRKEWKDVLSGGEKQRMAFARLLYHEPRYAFIDEgtsavssdveglLYERSKEkgitlitistR-------A--Slkkyhtfqltlglg 741
                 36655553444444444444555555555555555444444444333333344444222222222222221111.......1..122333444455666 PP

      AAA_23 143 ....feefelkdkkerleelekeleeledekkllekle.qekekekele 186
                     ++ef++  ++++   +ekel+el ++ + +e ++ +++e e el+
  EEA21604.1 742 msgdEWEFDRIGTEKEKMGVEKELQELRKRLDNVEGWKrRREEIESELN 790
                 6666777777556666666666666666666666665413333333444 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   6.8e-05      0.12       1      20 [.     565     584 ..     565     607 .. 0.89
   2 ?   -3.2   0.0         6   1.1e+04      46     110 ..     676     724 ..     667     728 .. 0.58

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 6.8e-05
                 EEEESSTTSSHHHHHHHHHH CS
         AAA   1 vllyGppGtGKTllakavak 20 
                 +l++Gp G+GK+++a+ va 
  EEA21604.1 565 LLICGPNGVGKSSIARIVAG 584
                 689***************97 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 6
                 HHHHHHHHHHTSTSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTSSSTEEEEEEES CS
         AAA  46 irelfkeakekakpsilfiDEidalaksrsgseseeeervvnqLlteldgvkkkeskvivigatn 110
                  r+ f+++  ++ p   fiDE  + ++s+           v+ Ll e +++k     +++i++++
  EEA21604.1 676 QRMAFARLLYHE-PRYAFIDEGTSAVSSD-----------VEGLLYERSKEKG----ITLITIST 724
                 555555544443.6666788877777776...........5555544444444....55555555 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       3.6   6.4e+03      35      49 ..     106     120 ..     106     123 .. 0.80
   2 ?   10.5   0.0   0.00021      0.38      22      38 ..     561     578 ..     553     580 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 3.6
      AAA_29  35 KSTllDAiqalLvpa 49 
                 K T +DA+  l++ +
  EEA21604.1 106 KPTTFDAHRRLFLNP 120
                 67999***9998866 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00021
      AAA_29  22 kg.atlltGpsGsGKSTl 38 
                 +g   l+ Gp+G+GKS++
  EEA21604.1 561 SGeHLLICGPNGVGKSSI 578
                 34489***********97 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00012      0.21      19      47 ..     560     587 ..     547     591 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00012
  Mg_chelatase  19 aaGgHnlllvGppGsGKtmlakrlpsllp 47 
                    +G+ +ll++Gp G GK+ +a+ +++l p
    EEA21604.1 560 HSGE-HLLICGPNGVGKSSIARIVAGLWP 587
                   4455.5999*************9999987 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00015      0.26      33      54 ..     562     583 ..     552     596 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00015
      RuvB_N  33 ldhvllyGpPGlGkttlakiia 54 
                  +h+l++Gp G+Gk+++a+i+a
  EEA21604.1 562 GEHLLICGPNGVGKSSIARIVA 583
                 58******************99 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00015      0.27      38      65 ..     552     580 ..     540     585 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00015
   IstB_IS21  38 Latlsfi.ekkenivllGpsGvGKshlai 65 
                 + +lsfi ++ e ++++Gp GvGKs +a 
  EEA21604.1 552 IESLSFIvHSGEHLLICGPNGVGKSSIAR 580
                 4678886256899************9985 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       2.7   4.8e+03       7      54 ..      45      99 ..      43     104 .. 0.81
   2 ?   10.4   0.0   0.00033      0.59       4      24 ..     561     581 ..     559     591 .. 0.87

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 2.7
      AAA_22  7 ilvvtGesGtGKTtllrrlleqldeeakaee.......erpevvfvtlpsstssk 54
                i++++G s  G ++l +r +e ++ +   ++        ++++++v  + s++sk
  EEA21604.1 45 IIAIIGSSYGGYSFLHKRSTEHAQGRRLLRRnsglrgkDGSRIIYVPYKDSMTSK 99
                7899999999999999999999988888877888888888888888888777665 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00033
      AAA_22   4 tagilvvtGesGtGKTtllrr 24 
                 +  +l+++G+ G+GK+  +r 
  EEA21604.1 561 SGEHLLICGPNGVGKSSIARI 581
                 56799***********99985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (816 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       655  (0.036533); expected 358.6 (0.02)
Passed bias filter:                      601  (0.0335211); expected 358.6 (0.02)
Passed Vit filter:                        95  (0.00529868); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.77u 0.32s 00:00:01.09 Elapsed: 00:00:00.48
# Mc/sec: 5107.44
//
Query:       EEA21605.1  [L=242]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (242 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       355  (0.0198003); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.23s 00:00:00.65 Elapsed: 00:00:00.39
# Mc/sec: 1857.74
//
Query:       EEA21606.1  [L=498]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.9e-22   78.0  36.7    1.1e-20   74.1  36.7    2.4  1  Acyl_transf_3  Acyltransferase family


Domain annotation for each model (and alignments):
>> Acyl_transf_3  Acyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.1  36.7   5.9e-25   1.1e-20       2     337 ..      75     472 ..      74     475 .. 0.81

  Alignments for each domain:
  == domain 1  score: 74.1 bits;  conditional E-value: 5.9e-25
                    xxxxxxxxxxxxxxxxxxxxx...........xxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxx..........xxxxxxxxxxx RF
  Acyl_transf_3   2 aylDllRgiAillVvflHali...........ayspdagrgspiqasqssqi...aflggfgvplFFllSGffla..........amlyrrrglsk 73 
                    a+lD++Rg+A+l+V+f+H +            + sp+a++ ++      ++i   ++ g+ +vp+F + SG  l+                +++s+
     EEA21606.1  75 AWLDGIRGCAALIVFFMHLSLsvqdshamlraYGSPGATSLWQ------LPIirlLYDGSPMVPIFYVTSGCALSlkplslihknEWADFSTTVSS 164
                    7*********************999865554333333333332......3336778*************************998533333467899 PP

                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..............................xxxxxxxxxxxxxxxxxxxxx RF
  Acyl_transf_3  74 likrRilrlliplliwllliillialvaghiqanasanvtlfdet..............................kglmfllfefpatghlWfLwa 139
                    + +rR +rl++p  i+++l +l+++l+++ + +++    +                                   +        +++  +lW++++
     EEA21606.1 165 ATFRRGFRLFLPSAIVSFLAMLFTQLGIYNHPYQFMEGNAII--IdrphrlpniaaqyvdwlnwmatqlfysedlFQPLSGTTISNYGFQLWTIST 258
                    9**************************999999664433333..2566**************************8777777777777789****** PP

                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............... RF
  Acyl_transf_3 140 lfvlylllplllrllrkvrkshlllllilllllslvfirhelfgpatsvgllplpsvlallfflfGalladaddrdrnlsr............... 220
                    +f  +++l++ l  l ++  s++ +l+++l+++s+++ r+e+                  + f +G+ +  ++ + +                   
     EEA21606.1 259 EFYASIALFIALVGLSRLAVSIRQVLVFCLCAFSFYIDRWEI------------------ACFMAGMSITELSIQAKDGHEsvslplfargksvst 336
                    *****************************************7..................556666666655555555555556666777777766 PP

                    xxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxx RF
  Acyl_transf_3 221 glkislllsllllalillalfgqtdg.....gglvasvliqsaslllvslgimllllllfalpsrsafk...llrylgkiSygiYliHlpllmllq 308
                      ++s+   ++ll++++l+++++ ++       +  +++  + ++++ s+g+ ++l+++  l+ +++ +   + rylg+iSyg+Yl H+++l++l+
     EEA21606.1 337 WILRSRQYMFALLFVAGLFIASYPYKeasnnFIYRPFSAVIDNARFWESMGAVCILVSASQLRLLQRLLtsiIPRYLGRISYGVYLTHVIFLNALG 432
                    6666666677777777777777776688777899999999999***********************9999************************** PP

                    xxxxxx.....xxx.......xxxxxxxxxxxxxxxxxxxx RF
  Acyl_transf_3 309 kllrdw.....gln.......lgevlllvlllvvsvivsvv 337
                      + +w     g n        g+++ l+++l++ v+++ +
     EEA21606.1 433 WRIVPWiweitG-NegwsnrqGGFAVGLIICLILLVWIADI 472
                    ******555551.0455557788888888888888888766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (498 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       541  (0.0301746); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.42
# Mc/sec: 3540.74
//
Query:       EEA21607.1  [L=253]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-24   87.6   0.0    1.4e-24   87.2   0.0    1.1  1  DUF3328   Domain of unknown function (DUF3328)


Domain annotation for each model (and alignments):
>> DUF3328  Domain of unknown function (DUF3328)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.2   0.0   7.6e-29   1.4e-24       7     219 ..      30     233 ..      22     234 .. 0.66

  Alignments for each domain:
  == domain 1  score: 87.2 bits;  conditional E-value: 7.6e-29
     DUF3328   7 ssawrrllllvlllllllllllilssllsssekkaak.kkspsspspaldaieyelkqfklgskeapsiyrgepspevdaaWddllkleailipree.l 103
                 +s+++r+   +l +l +ll+l+++  l+ ++ +++ +  +  s  +   ++i+ +l++f++ ++  ++    e    + ++W+ l+  ++ +++ ++ l
  EEA21607.1  30 RSQLSRS--PFLYILDFLLVLAVAFLLFRRHAYEKVRqFDLGSDITGYVPQIDHRLVTFTKEPQFISNHSSLESLRKAREHWKTLVPPGQGFVEVDDeL 126
                 4444444..2233333333333333333334333333212333344556677777777776666666666666666899***88888777776666634 PP

     DUF3328 104 rrlgkdpaaelevedkseggyiaglevfHqLHCLnllrkalypeyygypglsegeeeedrvHleHCidiLrqsimChaDvtlitfnwvkgtkgpvpdfn 202
                  +    p++ +  +d +e++y++g+ + H++HCL  ++       y+   l+ ++  +d++H++HC+d++rqs+mC +D+++ +    ++ +g   +f+
  EEA21607.1 127 VKGRAMPKRITWKQDGKEDKYMYGTAIVHSIHCLYSIM-----AEYDALALGLKSLPRDTLHMDHCFDYIRQSLMCAGDTSIAG----EDFPGGSYQFE 216
                 4444444344555556666***************4443.....4445888999999999************************4....445777777** PP

     DUF3328 203 tehqCrdfealldWaee 219
                 + h Cr+++++ dW ++
  EEA21607.1 217 VVHVCRNWDQIYDWLDA 233
                 **************765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (253 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       627  (0.0349713); expected 358.6 (0.02)
Passed bias filter:                      547  (0.0305092); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 1710.85
//
Query:       EEA21608.1  [L=255]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.037   13.8   3.3         12    5.6   0.0    3.0  3  DUF3328   Domain of unknown function (DUF3328)


Domain annotation for each model (and alignments):
>> DUF3328  Domain of unknown function (DUF3328)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0   0.00065        12       7      60 ..      33      86 ..      28     104 .. 0.55
   2 ?    4.7   1.1    0.0013        23     150     173 ..     175     198 ..     156     202 .. 0.67
   3 ?    1.8   0.0    0.0094   1.7e+02     131     142 ..     219     230 ..     212     243 .. 0.84

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.00065
     DUF3328  7 ssawrrllllvlllllllllllilssllsssekkaakkkspsspspaldaieye 60
                ++++r++ +++ +l+l+ +l++++ s+++++  + ++   +++ s+  d+++++
  EEA21608.1 33 KKSYRISKIILYSLFLVAILIITAISIATQKILTTNTRGEHPNNSQNSDSFDLS 86
                344444444444444445555555555555555555545555666666555554 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.0013
     DUF3328 150 gypglsegeeeedrvHleHCidiL 173
                 + ++++   ++e+ +H+ HCi  L
  EEA21608.1 175 QAMSTERLMYTEHSWHVNHCIYAL 198
                 455555556666*********987 PP

  == domain 3  score: 1.8 bits;  conditional E-value: 0.0094
     DUF3328 131 fHqLHCLnllrk 142
                  H LHC+ ++r 
  EEA21608.1 219 PHTLHCMMVFRM 230
                 599999999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (255 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       721  (0.0402142); expected 358.6 (0.02)
Passed bias filter:                      561  (0.0312901); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 1714.33
//
Query:       EEA21609.1  [L=776]
Description: saccharolysin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   1.7e-145  485.8   0.0   2.2e-145  485.4   0.0    1.1  1  Peptidase_M3  Peptidase family M3


Domain annotation for each model (and alignments):
>> Peptidase_M3  Peptidase family M3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  485.4   0.0  1.3e-149  2.2e-145       9     457 ..     304     773 ..     297     774 .. 0.97

  Alignments for each domain:
  == domain 1  score: 485.4 bits;  conditional E-value: 1.3e-149
                   HHHHHHHHHHCTTTCCSS..THHHHHHHHHHHHHHHHHHHTT-SSHHHHHHTTSTT-SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC...... CS
  Peptidase_M3   9 elRkeayeashskaaeqrntlensklleellklraelAkllgyesyaelaledkmaknpetvldfleelvkklrpllekelkllkelkkke...... 99 
                   e+R+++y ++ +k +      +n++l++e+++lr+e A+llgy+++a++++edkma++ e+v  fl +l+++l+p + ke++ l++lk ++      
    EEA21609.1 304 ETRQKLYVQNENKLN------QNVPLFREAIILRDEAARLLGYPDHASFRIEDKMAESAESVISFLGDLKERLTPGGAKEVAHLSQLKSEDlksrgl 394
                   899999999999977......79********************************************************************999775 PP

                   .CT-S..SS--CCCHHHHHHHHHCCCCS--CCCCGGG-BHHHHHHCHHHHHHHHHTEEEEEETTS.............--SSTT-EEEEEEET..TT CS
  Peptidase_M3 100 .lgle..gelqpwDvaYYsekqreekydldqeelkeyfpletvleGllelfeeLfGikfveekdak...........gevwhedVrkleVvde.ils 181
                       +  g+++ wD ++Y++ +  +++++d++ ++eyfpl+ ++eG+l++feeL G  fve   a+           + +whedV++++V+d+  + 
    EEA21609.1 395 aH--TndGNYYLWDDRFYDQLMVSKEFSFDEQLIAEYFPLQSTIEGMLAIFEELMGFVFVELGSADgakisptgksaDITWHEDVKIFSVWDDeGEG 489
                   32..1479****************************************************999999999************************999* PP

                   -EEEEEEEEEEC--TTS-SS-EEEEEE--B..TTS-B--EEEEEEEEE---BTTS--B--HHHHHHHHHHHHHHHHHHC--BSSGGGSTT-S-CCCC CS
  Peptidase_M3 182 egligeiylDlyerkgKrggAasfglvksr..edgtrqlpviylllNftkpsskkPsLLtldevetLfHEfGHsmHsllsrteysnvsgtnvpidfv 276
                   +g++g++y+Dl++r+gK g+Aa+f l++++   +gtr++p+++l++Nf+kp+++kPsLL++de+  LfHE+GH++H+l +rt+ys+++gtnv +dfv
    EEA21609.1 490 NGFVGYFYMDLHPRPGKFGHAANFALQPGFilPNGTRRYPATALVCNFSKPAKDKPSLLKHDEIVLLFHELGHGIHDLAGRTRYSQFHGTNVVRDFV 586
                   *****************************98769*************************************************************** PP

                   CHHHHHHHHGGGSHHHHHCC-B-TTT--B--HHHHHHHHCCCCTTHHHHHHHHHHHHHHHHHCTT-TCCGHH....HHHHHHHHHHCTTSCTTBT.. CS
  Peptidase_M3 277 ElpSqlmEnlltepevlkslskhyetgeaipeelleklikaknvnaalellrqlvfaafdqelHeeaeeeqilkkdlletyaelrkkflglpvap.. 371
                   E+pSq++E+++++ +vlkslskhy+tge+ip++l+ kli +k+vn al++l ql+f+ fd+e+H+  ++++ ++ + +e y+++r +++gl+  +  
    EEA21609.1 587 EAPSQMLEYWCWNSSVLKSLSKHYKTGEQIPDNLIAKLISTKHVNGALDNLHQLHFGIFDMEVHTPRSHKESESINYSELYNDIRAQTYGLKGLEal 683
                   ***********************************************************************99999**************8888888 PP

                   .....TSSGGGC-CCCHTSS-TTTTCHHHHHHHHHHHHHHCCHHCCTT-CCHHHHHHHHTTTTTTSS-HHHHHHCCCSS---SHHHHHHCT CS
  Peptidase_M3 372 .....deasqasFghlfahgYaanYYsylyaevlaldifekffeedplnretGeryrkeiLsrGgskdplellkkflgrepsadallkalg 457
                        + + +a Fghl+ + Y+a+YY+yl ++v+++d+f+++fe+dp+n + G+ryr  +L++Ggs++++++l++flgr+ps++a++k+lg
    EEA21609.1 684 gvrsdWGHGEAIFGHLM-GEYDAGYYGYLSSQVYSADMFSSVFEKDPMNGKEGRRYRHMVLEKGGSQQEIKILEDFLGRKPSTEAFYKELG 773
                   99888999999*****7.*******************************99*************************************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (776 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       467  (0.0260472); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.71u 0.33s 00:00:01.04 Elapsed: 00:00:00.53
# Mc/sec: 4440.03
//
Query:       EEA21610.1  [L=187]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-17   63.2   2.3    2.1e-17   63.2   2.3    2.0  2  GFA       Glutathione-dependent formaldehyde-activating enzym


Domain annotation for each model (and alignments):
>> GFA  Glutathione-dependent formaldehyde-activating enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.2   2.3   1.2e-21   2.1e-17       2      92 ..      32     126 ..      31     127 .. 0.92
   2 ?   -0.8   0.0      0.11     2e+03      15      39 ..     148     175 ..     146     185 .. 0.52

  Alignments for each domain:
  == domain 1  score: 63.2 bits;  conditional E-value: 1.2e-21
         GFA   2 lChCsdCrkasgsaftanavvkaealelleg.elkeykktadsgnkvtrsfCpeCgsplyse.esaapevvivrvGtlddp..eklkpeaeiftk 92 
                 +ChC+ C++ sg+a+++na++++++++++++ +++  +  ++sg++ +   Cp+C + + ++  ++   +++v+vGtld +  ++++p+++i+t+
  EEA21610.1  32 CCHCTWCQRESGAAYALNAIIETSNFRITSEtQPTITDLPTNSGDGQKIARCPKCYVVIACDyGDNFTWTTFVKVGTLDGEsrKNVRPDVHIYTT 126
                 7**************************999976665555599999999999**********9999***************99999********96 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.11
         GFA  15 aftanavvkaeale...llegelkeykk 39 
                 +++a+ v++++ale   +l+ ++k+ ++
  EEA21610.1 148 GYKAVQVWRKDALErfeVLKQKMKKAEE 175
                 5667777777766622244444444333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (187 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1069  (0.0596241); expected 358.6 (0.02)
Passed bias filter:                      428  (0.0238719); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 1238.94
//
Query:       EEA21611.1  [L=394]
Description: hypothetical protein PMAA_054120 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.7e-07   31.2  12.7    3.2e-07   30.4  12.7    1.4  1  Zn_clus     Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.086   12.7   1.2       0.19   11.6   0.1    1.8  2  Leukocidin  Leukocidin/Hemolysin toxin family


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.4  12.7   3.6e-11   3.2e-07       1      34 [.      24      56 ..      24      60 .. 0.92

  Alignments for each domain:
  == domain 1  score: 30.4 bits;  conditional E-value: 3.6e-11
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfys 34
                +aCd+C++ Kv Cd+++P+C++C+ +++ Ct ys
  EEA21611.1 24 KACDQCHRCKVACDGGRPTCQRCAMNESACT-YS 56
                59*****************************.65 PP

>> Leukocidin  Leukocidin/Hemolysin toxin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.1      0.13   1.2e+03      79     115 ..      51      92 ..      47     102 .. 0.83
   2 ?   11.6   0.1   2.1e-05      0.19     146     219 ..     161     235 ..     148     248 .. 0.74

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.13
                 EEEEEECC...TEE...CCCCCS-S..-EEEEEEEEEEEE-T CS
  Leukocidin  79 etlgYslG...Gkv..skdgpklggeitgsfnysktlsYkqk 115
                 +  +Ys+G   Gk   sk+++kl+++  gs+    tl+ k +
  EEA21611.1  51 SACTYSTGkpiGKPkgSKNRNKLEAQKPGSNQADSTLNHKRQ 92 
                 678999998888879999999999999999999999998876 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 2.1e-05
                 ..TSEECTTBTCTTB--SSSCCTTTCGGGBB-GGGS-CCCTTEE--EEEEEEE..EESTS-SEEEEEEEEEEEEEEE CS
  Leukocidin 146 t.dsqksaydneLfvksrnstaalwakdyfvdknklpplvysgFnPefiavls..aekketgksefeitykrnidai 219
                   d+++ +++n++   +  +t   + ++  ++++ lp + +s+F+P++++++   ++ +e  +++  i+  rn+ + 
  EEA21611.1 161 AgDEFNLTFENDIEDWN--NTMVDDNQQKAAPNTYLPTVDQSSFSPDVLTLVGkmHDSNEMANTKAPIEIPRNANQS 235
                 34888888999886666..45578999999*********************96224556666777777777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (394 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       729  (0.0406604); expected 358.6 (0.02)
Passed bias filter:                      431  (0.0240393); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.41
# Mc/sec: 2855.23
//
Query:       EEA21612.1  [L=288]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.7e-24   84.3  51.4    6.6e-23   80.8  51.4    2.0  1  Fibrinogen_BP  Fibrinogen binding protein
  ------ inclusion threshold ------
       0.34   11.2  62.9        2.3    8.6   0.9    9.6  8  DUF4169        Domain of unknown function (DUF4169)


Domain annotation for each model (and alignments):
>> Fibrinogen_BP  Fibrinogen binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.8  51.4   7.3e-27   6.6e-23      14     293 ..      44     282 ..      12     288 .] 0.56

  Alignments for each domain:
  == domain 1  score: 80.8 bits;  conditional E-value: 7.3e-27
  Fibrinogen_BP  14 spvsamdsvgnqsqgnvlerrqrdaenrsqgnvlerrqrdaenrsqgnvlerrqrdaenrsqgnvlerrqrdaenrsqgnvlerrqrdaenrsqgn 109
                    s+v a d  g ++qg+   + qrd e+  + + l+  +rd + ++qg+   + qrd e ++qg+     qrd + ++qg+     qrd + ++qg+
     EEA21612.1  44 SAVKARDLDG-KAQGKAQGKAQRDLEEDEEYEYLDIAERDLDGKAQGKAQGKAQRDLEGKAQGK----AQRDLDGKAQGK----AQRDLDGKAQGK 130
                    4455544433.35555555555555555555555555555555555555555555555555553....455555555553....455555555555 PP

  Fibrinogen_BP 110 vlerrqrdaenksqgnvlerrqrdaenrsqgnvlerrqrdaenrsqgnvlerrqrdaenrsqgnvlerrqrdaenksqgnvlerrqrdaenrsqgn 205
                       + qrd e k+qg+     qrd + ++qg+     qrd e ++qg+     qrd + ++qg+   + qrd e k+qg+   + qrd e ++qg+
     EEA21612.1 131 AQGKAQRDLEGKAQGK----AQRDLDGKAQGK----AQRDLEGKAQGK----AQRDLDGKAQGKAQGKAQRDLEGKAQGKAQGKAQRDLEGKAQGK 214
                    5555566655555553....455555555553....455666555553....45666666666666666666666666666666666666666653 PP

  Fibrinogen_BP 206 vlerrqrdaenrsqgnvlerrqrdaenrsqgnvlerrqrdaenksqgnvlerrqrdaenrsqgnvlerrqrdaenrsqgnvlerrqrd 293
                         qrd e ++qg+     qrd e ++qg+     qrd e k+qg+   + qrd e ++qg+     qrd + ++qg+     qrd
     EEA21612.1 215 ----AQRDLEGKAQGK----AQRDLEGKAQGK----AQRDLEGKAQGKAQGKAQRDLEGKAQGK----AQRDLDGKAQGK----AQRD 282
                    ....456666666653....456666666653....4666666666666666666666666663....456666666653....3444 PP

>> DUF4169  Domain of unknown function (DUF4169)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.1      0.15   1.3e+03      33      43 ..      28      38 ..      25      56 .. 0.70
   2 ?    0.9   0.3     0.062   5.6e+02      33      53 ..      62      86 ..      55      88 .. 0.72
   3 ?    6.3   5.2    0.0013        12      23      53 ..      94     126 ..      86     128 .. 0.60
   4 ?    8.4   1.0   0.00029       2.6      32      53 ..     133     154 ..     131     155 .. 0.93
   5 ?    8.6   0.9   0.00026       2.3      33      53 ..     158     178 ..     156     180 .. 0.93
   6 ?    2.5   5.9      0.02   1.8e+02      32      53 ..     201     222 ..     178     224 .. 0.87
   7 ?    6.7   1.2   0.00095       8.5      32      53 ..     225     246 ..     223     248 .. 0.93
   8 ?    6.4   5.0    0.0012        11      23      53 ..     254     286 ..     246     287 .. 0.58

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.15
     DUF4169 33 Kaekeleeaea 43
                Ka+++ ++a++
  EEA21612.1 28 KAQRDVDAARE 38
                67777777765 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.062
     DUF4169 33 Kaekeleeaea....erakrrlDgh 53
                Ka+++lee e+    + a+r+lDg+
  EEA21612.1 62 KAQRDLEEDEEyeylDIAERDLDGK 86
                8899998888744445677777775 PP

  == domain 3  score: 6.3 bits;  conditional E-value: 0.0013
     DUF4169  23 eeNRakFGrt..KaekeleeaeaerakrrlDgh 53 
                 +++R   G++  Ka+++l+ + + +a+r+lDg+
  EEA21612.1  94 KAQRDLEGKAqgKAQRDLDGKAQGKAQRDLDGK 126
                 444444443222777777777777777777775 PP

  == domain 4  score: 8.4 bits;  conditional E-value: 0.00029
     DUF4169  32 tKaekeleeaeaerakrrlDgh 53 
                  Ka+++le + + +a+r+lDg+
  EEA21612.1 133 GKAQRDLEGKAQGKAQRDLDGK 154
                 59******************97 PP

  == domain 5  score: 8.6 bits;  conditional E-value: 0.00026
     DUF4169  33 KaekeleeaeaerakrrlDgh 53 
                 Ka+++le + + +a+r+lDg+
  EEA21612.1 158 KAQRDLEGKAQGKAQRDLDGK 178
                 9******************97 PP

  == domain 6  score: 2.5 bits;  conditional E-value: 0.02
     DUF4169  32 tKaekeleeaeaerakrrlDgh 53 
                  Ka+++le + + +a+r+l+g+
  EEA21612.1 201 GKAQRDLEGKAQGKAQRDLEGK 222
                 59******************97 PP

  == domain 7  score: 6.7 bits;  conditional E-value: 0.00095
     DUF4169  32 tKaekeleeaeaerakrrlDgh 53 
                  Ka+++le + + +a+r+l+g+
  EEA21612.1 225 GKAQRDLEGKAQGKAQRDLEGK 246
                 59******************97 PP

  == domain 8  score: 6.4 bits;  conditional E-value: 0.0012
     DUF4169  23 eeNRakFGrt..KaekeleeaeaerakrrlDgh 53 
                 +++R   G++  Ka+++l+ + + +a+r+lDg+
  EEA21612.1 254 KAQRDLEGKAqgKAQRDLDGKAQGKAQRDLDGK 286
                 444444443222777777777777777777775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (288 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       465  (0.0259356); expected 358.6 (0.02)
Passed bias filter:                      120  (0.00669307); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 1990.94
//
Query:       EEA21613.1  [L=283]
Description: hypothetical protein PMAA_054140 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00086   19.1   5.0     0.0034   17.2   5.0    1.8  1  DUF3328   Domain of unknown function (DUF3328)
  ------ inclusion threshold ------
        0.2   10.6   0.0       0.29   10.1   0.0    1.1  1  DUF1057   Alpha/beta hydrolase of unknown function (DUF1057)


Domain annotation for each model (and alignments):
>> DUF3328  Domain of unknown function (DUF3328)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   5.0   3.8e-07    0.0034       5     171 ..      61     244 ..      57     250 .. 0.71

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 3.8e-07
     DUF3328   5 krssawrrllllvlllllllllllilssllsssekkaak........kkspsspspaldaieyelkqfk.....lgskeapsiyrgepspevdaaWddl 90 
                 +r ++++ ++ +++l++ +l ll+il   ++ ++++  +         + ++s+s ++    ++ ++ k     +       + +  +++e+d+ + + 
  EEA21613.1  61 RRYRFLVGCVTTLTLIFSILQLLAILRGGMHIPHREEVApnqslekhEPETTSSSNFDWPCGISAEEAKkagcyFDMGLIAWLPHACYNKELDESF-RA 158
                 677777788888888888888888887766666666655567877777777777777777777777777877663333334444445555777777.66 PP

     DUF3328  91 lkleailipree..lrrlgkdpaaelevedkseg.......gyiaglevfHqLHCLnllrkalypeyygypglsegeeeedrvHleHCid 171
                 l+  ++++p++e   ++l+k+  ++++ +d + +       g+ +++ +fH+ HCL + ++++++    ++++ +++ ++ + H+ HC +
  EEA21613.1 159 LNDWPFWLPNDEntGPNLTKPI-TVERLQDLPLQmvdldwpGHSWSTLMFHDAHCL-HAWQYMHQALL-KNKKIPTSITR-WSHTTHCSH 244
                 6666888888887866666666.555555444445556666***************.89999999999.99999999998.*******76 PP

>> DUF1057  Alpha/beta hydrolase of unknown function (DUF1057)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   3.3e-05      0.29      57     124 ..     184     252 ..     180     262 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 3.3e-05
     DUF1057  57 kleelkiRligvnyPGfefvtgylgqkytnaeRnsyskalleelelkgklillghsRGce.naLqlavt 124
                 +l++l + ++ +++PG +  t   ++ ++ +  +   +all++ ++   +   +h   c  +aL+ +++
  EEA21613.1 184 RLQDLPLQMVDLDWPGHSWSTLMFHDAHCLHAWQYMHQALLKNKKIPTSITRWSHTTHCShEALMDTSN 252
                 6888899999*********************************************99885268887776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (283 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       338  (0.0188521); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.46
# Mc/sec: 1843.78
//
Query:       EEA21614.1  [L=546]
Description: sucrose transport protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.1e-10   39.8   7.2    2.1e-10   39.8   7.2    2.6  3  MFS_2         MFS/sugar transport protein
  ------ inclusion threshold ------
        1.1    9.0   4.0        3.7    7.3   0.0    3.4  4  TMEM208_SND2  SRP-independent targeting protein 2/TMEM208


Domain annotation for each model (and alignments):
>> MFS_2  MFS/sugar transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.8   7.2   2.3e-14   2.1e-10      26     253 ..      94     333 ..      71     343 .. 0.70
   2 !    4.5   0.9    0.0012        11     284     340 ..     402     457 ..     354     465 .. 0.67
   3 ?   -3.3   0.1      0.27   2.4e+03     149     184 ..     501     536 ..     484     544 .. 0.49

  Alignments for each domain:
  == domain 1  score: 39.8 bits;  conditional E-value: 2.3e-14
       MFS_2  26 dvlglsaalvglvllvarlvDaitDpivGtlidktstrwGrrrPwlllsaiilavsiillftppelsqs...............akfiwllvtyillri 109
                   lg s +  +l+  +  +   ++ pivG+++d+++ rwGrrrP++l +ai +a+s+i+l ++ ++  +                + i ++v+ + l +
  EEA21614.1  94 YSLGSSKSQSSLIWAIGPICGTVVQPIVGAIADNSRIRWGRRRPFILGGAIGTAISLIALAWVSNIMHAlaatvnihsdegvktMTQIGIIVCITFLNL 192
                 44577777778888888888999******************************************999999******8888876666666667777788 PP

       MFS_2 110 lytlfeipyvslvpvltkdydeRtsltsvrsflsvlggvlaailafllvlilgglkserkgylifaliialLmllgviivvlgtkervem.rkkekteq 207
                  +  ++    +l++ +   +++ + ++++   +s +  +l+ il +l ++i +   +e  +++ +al+ ++    +v+++v++ +e++   +    +e 
  EEA21614.1 193 SIQPLQSGLRALIVDI-CPSEQQSVASAWAGCFSGFSNILGYILGSLPLGIVSH-DNEVWRFRFLALVSVAALGTTVLLAVYFIREEDPReFVYAPEEG 289
                 8888888889999999.56778899999***************99999999998.55555555555444333333455555666666554233333333 PP

       MFS_2 208 keklslleqlkevfrnraflillllfllaalalgvlnglllYylty 253
                    +++l+ +k++ ++ ++     ++l++++a + ++g +l+y t 
  EEA21614.1 290 MLLVRVLRTVKNSWSSMPAQSQ-RVCLVQFFAWMGWFG-FLFYSTS 333
                 3344555555555555444433.234555555555555.3444444 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.0012
       MFS_2 284 krlgkkntyllgalltivllvlvlllqpsnlllflvllviagfgvgvaallpwsmla 340
                 +++   +++ +++ l+ ++ +++ ++  s++ +++++ ++ag++ gv + +p ++l+
  EEA21614.1 402 RWWRQTHIIWAMSHLLYAFCAFCTFF-ISSTNTAVLVIAVAGISWGVTQWAPFALLG 457
                 34444444444455555566666666.677777777778888888888777777776 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 0.27
       MFS_2 149 laailafllvlilgglkserkgylifaliialLmll 184
                 laa+  + +++i++g  s+ +  ++++l i+ L++l
  EEA21614.1 501 LAAVASSFVFVIFEGDRSDGDSGIVWVLRISGLAAL 536
                 333333333333333344444444444444444444 PP

>> TMEM208_SND2  SRP-independent targeting protein 2/TMEM208
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.1     0.083   7.4e+02       5      50 ..      49      94 ..      47     106 .. 0.79
   2 ?   -3.0   0.0      0.61   5.4e+03      18      42 ..     253     277 ..     249     284 .. 0.72
   3 ?   -0.4   0.1     0.099   8.9e+02      40      66 ..     317     343 ..     305     348 .. 0.81
   4 ?    7.3   0.0   0.00042       3.7       5      60 ..     392     447 ..     388     480 .. 0.75

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.083
  TMEM208_SND2  5 saKkiaeeNkatLknlrlislavnalylllrlllrsslrprsllly 50
                  s+ ++a+ N ++Lk  +++++a++  ++ l+l+ +s ++  +  ly
    EEA21614.1 49 STTTLATDNLQVLKLPTRLIIALTCGFAGLQLVWSSIFSHGTAYLY 94
                  5667899999999999999999999999999999666666655555 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.61
  TMEM208_SND2  18 knlrlislavnalylllrlllrssl 42 
                   ++l l+s+a+ + ++ll +++ ++ 
    EEA21614.1 253 RFLALVSVAALGTTVLLAVYFIREE 277
                   6788888888888888888884443 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 0.099
  TMEM208_SND2  40 sslrprslllylllslpalllyyvlek 66 
                   + + +  ++++l+ s+ +++ +y+ e+
    EEA21614.1 317 QFFAWMGWFGFLFYSTSYVGRLYMTES 343
                   5578999**********9999998775 PP

  == domain 4  score: 7.3 bits;  conditional E-value: 0.00042
  TMEM208_SND2   5 saKkiaeeNkatLknlrlislavnalylllrlllrsslrprslllylllslpalll 60 
                   s+K i ++ ++  +++++i +++++ly++  +     ++ ++ +l+++++ +++++
    EEA21614.1 392 SEKPILQSRSRWWRQTHIIWAMSHLLYAFCAFCTFFISSTNTAVLVIAVAGISWGV 447
                   889999999*******************9999882233333344444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (546 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       614  (0.0342462); expected 358.6 (0.02)
Passed bias filter:                      282  (0.0157287); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.42
# Mc/sec: 3940.08
//
Query:       EEA21615.1  [L=777]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-31  110.5   0.2      4e-31  108.8   0.0    2.0  2  Clr2          Transcription-silencing protein Clr2
    7.4e-19   68.3   0.5    1.8e-18   67.1   0.5    1.7  1  Clr2_transil  Transcription-silencing protein, cryptic loci r
  ------ inclusion threshold ------
       0.36   10.8   5.6       0.56   10.1   5.6    1.2  1  TFIIA         Transcription factor IIA, alpha/beta subunit
        3.6    7.3   6.6        6.4    6.4   6.6    1.3  1  Cwf_Cwc_15    Cwf15/Cwc15 cell cycle control protein
          4    5.4   6.5        5.8    4.9   6.5    1.1  1  DNA_pol_phi   DNA polymerase phi
        4.8    7.4   7.6         16    5.8   2.4    3.2  2  AT_hook       AT hook motif


Domain annotation for each model (and alignments):
>> Clr2  Transcription-silencing protein Clr2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  108.8   0.0   1.4e-34     4e-31       1     146 []     415     547 ..     415     547 .. 0.95
   2 ?   -2.5   0.1       2.6   7.8e+03      29      60 ..     681     712 ..     670     720 .. 0.66

  Alignments for each domain:
  == domain 1  score: 108.8 bits;  conditional E-value: 1.4e-34
        Clr2   1 yyqGvylGaEriwvgDtVRlkpsesdnnlasklelssdasndkadvlvideIqvllktadee....dleeketirlaGkvytlvrkraykppssnaapp 95 
                 y++G++lG E+i+vgDtVRlk++  +           +   +++dv+vi+ I+++l++++++    +l+++++ir++G++y+  ++ra ++p+      
  EEA21615.1 415 YCRGMFLGPEMIVVGDTVRLKAKGAT----------VNRLAPVTDVMVIKRIEFRLNSCIKDpqspHLAKSYSIRIRGNIYSNLPTRACRNPDGYG--- 500
                 9*************************..........89999***********************************************97544433... PP

        Clr2  96 akpkpleavvieelpkgfkavelrkygewyrvh.sgkevelsendvaGRfYe 146
                   ++pl++   +e++++f++v++++yg+wyr h +g  ve+s+++++GR+Ye
  EEA21615.1 501 --SQPLNQ---QEVIDAFQQVGMSEYGAWYRTHrPGTAVEISHDMIIGRCYE 547
                 ..579999...99**************************************7 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 2.6
        Clr2  29 lasklelssdasndkadvlvideIqvllktad 60 
                 +++  ++ss++ ndka+ +++ +I+  +++ +
  EEA21615.1 681 NDETVNTSSEEDNDKAEEMDMVAIKGSTTNSP 712
                 45566777777777777777777776665555 PP

>> Clr2_transil  Transcription-silencing protein, cryptic loci regulator Clr2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.1   0.5   5.9e-22   1.8e-18       1      68 []      68     148 ..      68     148 .. 0.97

  Alignments for each domain:
  == domain 1  score: 67.1 bits;  conditional E-value: 5.9e-22
                   -EESS--TT-EEEEE--------................---EEEEE--TTS--B-SHHHHHHHHHHHHH-TT--GGG--SHHH CS
  Clr2_transil   1 yvLkelPagYalyehqkgkeekn................erkdtyLyGhpsgkrfrSpaeflpHllwLltdkekdvknCsCklC 68 
                   y+Lk+lPa+Y+l+++++ ++++                 +++d+++yGhpsg+ f+Sp++f+pH++wL+++k++    C+C++C
    EEA21615.1  68 YILKQLPAQYSLMDRPRFSDNTIvsaspfpfvqmcltdlTQRDKFFYGHPSGAPFNSPKNFFPHFYWLVSGKSGI---CPCDCC 148
                   9*******************988***********************************************88877...*****9 PP

>> TFIIA  Transcription factor IIA, alpha/beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   5.6   0.00019      0.56     307     375 ..     663     746 ..     585     749 .. 0.64

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00019
       TFIIA 307 ladlseilqlDGagddsdeeeeeeesdedsdsessddedeq....................veEDplNSdDDvddeddddlfdtdnviv 375
                 ++  s+ l + G +  s+++e+ ++s+e+++ ++ ++   +                    + +D +  +DD dd d+dd +d+d  ++
  EEA21615.1 663 SSLVSSGLNMEGSANVSSNDETVNTSSEEDN-DKAEEM--DmvaikgsttnsppdlarighSKDDGIKDGDDDDD-DEDD-WDEDPAVL 746
                 2245556666676666666333333322222.222222..22355566666777788999999*******88777.4456.78887665 PP

>> Cwf_Cwc_15  Cwf15/Cwc15 cell cycle control protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   6.6    0.0021       6.4     104     145 ..     684     742 ..     633     751 .. 0.50

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0021
                 ----..-----------------.....................-----...-----------.--- CS
  Cwf_Cwc_15 104 lleeareidaddedseeeeeeee.....................eesdd...dsdsdsddddd.ede 145
                 ++++++e d+d+ +        e                     +++dd   d d+d+dd+dd +++
  EEA21615.1 684 TVNTSSEEDNDKAE--------EmdmvaikgsttnsppdlarigHSKDDgikDGDDDDDDEDDwDED 742
                 11111122222222........123445556667777777777755555454333333333331344 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   6.5    0.0019       5.8     619     685 ..     660     743 ..     656     758 .. 0.59

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.0019
  DNA_pol_phi 619 ellldvLearenkegqaelfedededeeddeeeeeeddeededse.eddde..................eesdedeededdedvde 685
                  + + + +++  n eg a++   +de   +++ee++++ ee++ +  +  +                   +++d+d++dedd d+d+
   EEA21615.1 660 QKMSSLVSSGLNMEGSANVS-SNDETVNTSSEEDNDKAEEMDMVAiK-GSTtnsppdlarighskddgiKDGDDDDDDEDDWDEDP 743
                  56667777777778888776.44444444555555545555555532.22234577778888777666655555555555555544 PP

>> AT_hook  AT hook motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   2.4    0.0054        16       4      13 .]     189     198 ..     188     198 .. 0.87
   2 ?    2.9   0.2     0.045   1.3e+02       5      11 ..     649     655 ..     645     657 .. 0.79

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0054
     AT_hook   4 RGRPrKaatk 13 
                 RGRP+K a+k
  EEA21615.1 189 RGRPAKRASK 198
                 ******9875 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.045
     AT_hook   5 GRPrKaa 11 
                 GRP K++
  EEA21615.1 649 GRPSKSQ 655
                 *****97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (777 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       527  (0.0293937); expected 358.6 (0.02)
Passed bias filter:                      395  (0.0220313); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.64u 0.29s 00:00:00.93 Elapsed: 00:00:00.44
# Mc/sec: 5362.71
//
Query:       EEA21616.1  [L=359]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    0.00087   19.7   0.0     0.0021   18.5   0.0    1.8  1  2OG-FeII_Oxy  2OG-Fe(II) oxygenase superfamily
     0.0034   18.1   0.0     0.0064   17.2   0.0    1.4  1  DIOX_N        non-haem dioxygenase in morphine synthesis N-te


Domain annotation for each model (and alignments):
>> 2OG-FeII_Oxy  2OG-Fe(II) oxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.0   2.4e-07    0.0021      34     100 ..     264     334 ..     220     335 .. 0.86

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 2.4e-07
                   EEEE-TT---EE.EETEEEE----TTEEEEEE-HHHHHHTTS-S----EEE-.---GTGS..EEEEEEEE- CS
  2OG-FeII_Oxy  34 llqddvgglevf.kdgkwlrvppvdnslivniGdallflsngryksvlHrVl.pvneger..Rvsiayfie 100
                    + d+++gl++  ++g++++v+ ++++l  + G al++++ g+++ v+H V+ + +++ +  R ++a+f +
    EEA21616.1 264 SSPDPKAGLYIRsRTGEIVKVNIPKDCLAFQTGEALELITQGKFRAVPHFVKgALTTSGKiaRNTLAVFTQ 334
                   456779***99546699**********************************97776666466766766665 PP

>> DIOX_N  non-haem dioxygenase in morphine synthesis N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   7.2e-07    0.0064      24     117 ..      30     138 ..      20     139 .. 0.69

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 7.2e-07
      DIOX_N  24 eAcrevGffyvvnhgvp...eelidelfeaareFFalPeeeKeklaksp..sfrGysrlgeektdgkkldw.kesfdlgtelp..........eddp.. 104
                 eA+    + ++v  ++p   +el++++++ +  + +l+++e ekl++++     G+s  g+e++++++ d  k s+++++ +           +  +  
  EEA21616.1  30 EAFGPSSLGIIVVKDLPptfKELRAQVLSNSSYLASLSQDELEKLESPQskYLVGWSC-GKETLRSGHFDTlKGSYYINCAFYqnpelqnapaD--Efp 125
                 5554444444444444412469***********************666543889**99.88888884555438888888875434455444322..144 PP

      DIOX_N 105 agkplegpnqwPe 117
                 +  +++ pn+wP+
  EEA21616.1 126 DFPQYTAPNIWPD 138
                 77779*******8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (359 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       342  (0.0190752); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.25s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2540.53
//
Query:       EEA21617.1  [L=521]
Description: lysyl-tRNA synthetase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.7e-75  252.1   0.0      9e-75  251.7   0.0    1.1  1  tRNA-synt_2      tRNA synthetases class II (D, K and N)
    5.6e-10   39.1   0.0    1.2e-09   38.1   0.0    1.5  1  tRNA_anti-codon  OB-fold nucleic acid binding domain
    1.3e-05   24.8   0.1     0.0052   16.3   0.0    2.9  3  tRNA-synt_2d     tRNA synthetases class II core domain (F)
  ------ inclusion threshold ------
      0.052   13.8   0.0      0.098   12.9   0.0    1.5  1  tRNA_anti_2      OB-fold nucleic acid binding domain


Domain annotation for each model (and alignments):
>> tRNA-synt_2  tRNA synthetases class II (D, K and N)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  251.7   0.0     2e-78     9e-75       9     311 ..     181     516 ..     176     519 .. 0.91

  Alignments for each domain:
  == domain 1  score: 251.7 bits;  conditional E-value: 2e-78
                  HHHHC.CSHHHHHHHHHHHHHHHHHHHHHHHTT-EE----SEESS--SSSS--EEEEETTT.TEEE-E-S-SHHHHHHHHHCTHSEEEEEEEEE--S- CS
                  xxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2   9 ryldl.rtekvskvlrlrstvtkavrkyleengfieietPiLsksdteegarlFkvksrekekeffaLtqspqlylellivagidrvfqiaraFRaEd 105
                  r++++   +++s+++r+rs +++++r+++ e+ f+e++tPi+ ++++++ ar+F+++ +e +++  +L+++p+l+l++l+++g+d+vf+i+ +FR+E 
   EEA21617.1 181 RHVQFlADKRTSDIMRIRSAIIQYIRQFFVERAFMEVNTPIMASEAGGATARPFVTTANEFPDKSLYLRIAPELWLKRLVIGGFDKVFEIGASFRNEG 278
                  7888878999**********************************************99999776666******************************* PP

                  -BTTB-S-CEEEEEEEEET-SCHHHHHHHHHHHHHHHHHHHHCSCCCCCHTTTTTSEE-SSS-EEEEHHHHHHHHHTS.-SS--HHHHHHHHH..... CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxx..... RF
  tRNA-synt_2 106 srtdrhlaEFtqieaemsfieeedimqvleelikslvkevlessakdiefvirrnskdlkkpfkrltykeaieklnei.gkdldkaderalvk..... 197
                  +++++++ EFt++e++m++++ ed+m+++e l++ l+++v +++++ +++ i +  +++++pf+r+++   ie++ +    dl+++     vk     
   EEA21617.1 279 IDKSHNP-EFTTCEFYMAYANLEDVMSMTESLFSGLAEHV-TQHKERMNSEIPTPNTNFSAPFRRIDFIPGIEQAINRpLPDLSSPTAEEDVKqlfad 374
                  *******.********************************.6666777777777778***************99544345556655555555577778 PP

                  ........................HS--SEEEEEEEBGGGSTTCBBBSTTSTTBBSEEEEEETTEEEEEEEEB--SHHHHHHHHHHCCHH....SSSG CS
                  ........................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxx RF
  tRNA-synt_2 198 ........................keknepvfvtdfPaelkpFyarkeeddkkltesyDllingvElvgGslRiedpeeleeklkskgld....eeae 267
                                           +  ep+f+t+ P+ l+p+ ++  +++++++++ +l+i+g E+v+++ ++++p e+++k++++++     +e  
   EEA21617.1 375 lsiplpdlptlprlmdklcstylePQCIEPTFITHPPECLSPLSKSFLQNNQRVAARCELFIEGREYVNAYEEENSPWEQRQKFEQQKIFnqhtNEST 472
                  9999999999999999999999998889************************************************************9877777777 PP

                  GGGHHHHHHHHCT--SEEEEEEEHHHHHHHHCT-SSGGGCSSS- CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  tRNA-synt_2 268 ekfswylealeyGapphgGlglGldRlvmlllgsesIrdviaFP 311
                    ++ yl+a+e+G+pp+gG+g+G+dRlvml+++s+ I dv++F 
   EEA21617.1 473 GVDESYLQAMEWGLPPTGGWGCGIDRLVMLFTDSKRIGDVLPFK 516
                  8899*************************************995 PP

>> tRNA_anti-codon  OB-fold nucleic acid binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.1   0.0   2.6e-13   1.2e-09       1      76 []      77     159 ..      77     159 .. 0.97

  Alignments for each domain:
  == domain 1  score: 38.1 bits;  conditional E-value: 2.6e-13
                      EEEEEEEEEEEEEEETTEEEEEEEETTEEEEEEEET........HHHHHHHTTS-TTSEEEEEEEEEECTTSSEEEEEEEEEEE CS
  tRNA_anti-codon   1 VtvaGrvtsisdrsggkvifidlrDgtgriqvvlfr........eeatklaenlkeGdvvrvtGrvkrrpggelelkveeiell 76 
                      V+v+Gr+++ +  +g+k+if+dl  +  +iq +++         e+++ ++  l++Gd + +tG++ r+ +gel++kv+ei +l
       EEA21617.1  77 VVVQGRIRTAR-LAGSKLIFFDLVQNDHKIQGMWNLrmsadvtpEKFKVIYRLLRRGDALSITGKPHRTGRGELTIKVTEIPIL 159
                      89********9.*********************999********************************************9876 PP

>> tRNA-synt_2d  tRNA synthetases class II core domain (F)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0       0.2   9.1e+02      17      45 ..     196     224 ..     183     229 .. 0.79
   2 !   16.3   0.0   1.2e-06    0.0052     103     157 ..     266     318 ..     264     336 .. 0.85
   3 !    4.7   0.0     0.004        18     211     230 ..     489     508 ..     467     515 .. 0.80

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.2
                   SHHHHHHHHHHHHHHCTTCEESSTTSEEE CS
  tRNA-synt_2d  17 hpltkvleeikeiflelgfeevegpeves 45 
                   ++ + +++ i+++f+e  f ev+ p + s
    EEA21617.1 196 RIRSAIIQYIRQFFVERAFMEVNTPIMAS 224
                   566788999************99987655 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 1.2e-06
                   EEEEEEEEEBSST-SSSB-SEEEEEEEEEEETT--HHHHHHHHHHHHHHHCTSTE CS
  tRNA-synt_2d 103 kiisigrvfRrdavDathlaeFhqveglvvdenvsladlkgvleellkklfgaev 157
                   k++ ig  fR++ +D++h +eF+ +e+ ++    +l+d++ + e+l++ l +  +
    EEA21617.1 266 KVFEIGASFRNEGIDKSHNPEFTTCEFYMAY--ANLEDVMSMTESLFSGLAEHVT 318
                   899************************9986..6678999999999999866554 PP

  == domain 3  score: 4.7 bits;  conditional E-value: 0.004
                   EEEEEEEHHHHHHHHHT-SS CS
  tRNA-synt_2d 211 gfafGlGveRlamlkygieD 230
                     ++G G++Rl ml ++ + 
    EEA21617.1 489 TGGWGCGIDRLVMLFTDSKR 508
                   568***********987665 PP

>> tRNA_anti_2  OB-fold nucleic acid binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   2.2e-05     0.098      20      94 ..      75     156 ..      62     157 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2.2e-05
  tRNA_anti_2  20 kavwvrGeisnlkr.kasghvYftLkDekakisavifrsraaklk...ft.....ledGmkVlvkgrlsvYeprGsyqlivedi 94 
                  ++v+v+G i    r + s+ ++f+L+ ++ ki+ ++  + +a ++   f+     l+ G+ + ++g+++  + rG++ + v++i
   EEA21617.1  75 DEVVVQGRIRTA-RlAGSKLIFFDLVQNDHKIQGMWNLRMSADVTpekFKviyrlLRRGDALSITGKPHR-TGRGELTIKVTEI 156
                  679*********.6466*****************998877777776664455667899****99999875.6777777777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (521 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       487  (0.0271627); expected 358.6 (0.02)
Passed bias filter:                      456  (0.0254337); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 3564.36
//
Query:       EEA21618.1  [L=95]
Description: mitochondrial intermembrane space translocase subunit Tim10, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      2e-22   78.6   0.5    2.4e-22   78.3   0.5    1.1  1  zf-Tim10_DDP   Tim10/DDP family zinc finger
  ------ inclusion threshold ------
       0.13   12.6   0.1       0.15   12.4   0.1    1.3  1  Peptidase_S76  Serine peptidase of plant viral polyprotein, P


Domain annotation for each model (and alignments):
>> zf-Tim10_DDP  Tim10/DDP family zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.3   0.5   2.7e-26   2.4e-22       2      63 ..      17      79 ..      16      80 .. 0.96

  Alignments for each domain:
  == domain 1  score: 78.3 bits;  conditional E-value: 2.7e-26
  zf-Tim10_DDP  2 qleqeqqvanaqelvnkltekCfkkCi.gkypgssLdsseesCldnCvdryldvsnlvskrlq 63
                  + ++e++v+++ +l+n+lt++C kkCi ++y++++L+++e++Cld+Cv ++++v+ +vs+++q
    EEA21618.1 17 IAAAETEVEMVSDLFNRLTQSCTKKCIpPEYREGELNKGESVCLDRCVSKFFEVNIKVSEKMQ 79
                  5689***********************888*******************************98 PP

>> Peptidase_S76  Serine peptidase of plant viral polyprotein, P1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   1.7e-05      0.15      26      55 ..      14      47 ..       8      84 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 1.7e-05
  Peptidase_S76 26 ekkv.vanvt...vsDlakelteicveegiPiii 55
                   e+k+  a+++   vsDl + lt++c ++ iP + 
     EEA21618.1 14 EQKIaAAETEvemVSDLFNRLTQSCTKKCIPPEY 47
                   455533334322279****************775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (95 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       583  (0.0325172); expected 358.6 (0.02)
Passed bias filter:                      453  (0.0252663); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.39u 0.28s 00:00:00.67 Elapsed: 00:00:00.47
# Mc/sec: 601.82
//
Query:       EEA21619.1  [L=881]
Description: Sin3 complex subunit (Stb2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
  ------ inclusion threshold ------
      0.047   14.2   0.1        2.2    8.8   0.0    2.6  2  NPV_P10       Nucleopolyhedrovirus P10 protein
      0.055   12.2   0.1      0.089   11.5   0.1    1.2  1  Tektin        Tektin family
      0.065   13.4   0.1        5.8    7.2   0.0    3.5  4  PG_binding_1  Putative peptidoglycan binding domain
       0.84   10.2   3.4        2.2    8.8   3.4    1.6  1  APG6_N        Apg6 coiled-coil region
        2.4    8.5   5.1        1.5    9.2   0.9    2.5  2  DUF4164       Domain of unknown function (DUF4164)


Domain annotation for each model (and alignments):
>> NPV_P10  Nucleopolyhedrovirus P10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   0.0    0.0006       2.2       8      63 ..     737     794 ..     729     806 .. 0.84
   2 ?    2.9   0.4     0.043   1.6e+02      12      65 ..     791     842 ..     789     853 .. 0.63

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0006
     NPV_P10   8 vIradikavddkVdal.qqqvddvqenlpdvtelnekLdaqsaqLaele.tkvenIqd 63 
                 v ++d +a ++ V  l qq v  v+e++  v+ l++k +a+s++L  l  + +e+Iq+
  EEA21619.1 737 VLLSDAQAFSSGVLDLsQQTVPWVEEQVASVEFLHSKANALSEELGYLYpERIEDIQE 794
                 578899999998877747789*************************996358999987 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.043
     NPV_P10  12 dikavddkVd.alqqqvddvqenlpdvtelnekLdaqsaqLaeletkvenIqdiL 65 
                 di+++ ++ + +l ++  +++e++++++ l +kLd    +L+ le+k+e++++ L
  EEA21619.1 791 DIQELRERTNqVLGDEGSRLTEEMKKIELLGAKLDY---ELNVLESKIEDVEEGL 842
                 555555554314566667788888888888888875...4566666666665544 PP

>> Tektin  Tektin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.1   2.5e-05     0.089     218     302 ..     772     856 ..     759     861 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 2.5e-05
      Tektin 218 qasakLreaidsilkqtandlraqaeavnealrkrieetedaknkleeqlkkvleeiaeleknieeLekairdkeaplklaqtRl 302
                 +++ +L e++  +  +  +d+++ +e++n+ l +  + +++  +k+e   +k+  e++ le +ie+ e+ +++ ++++ +++ R+
  EEA21619.1 772 SKANALSEELGYLYPERIEDIQELRERTNQVLGDEGSRLTEEMKKIELLGAKLDYELNVLESKIEDVEEGLQEFQRHVDVVENRI 856
                 5677777777788888889999999999999999999999999999999999999999999999999999999999999999887 PP

>> PG_binding_1  Putative peptidoglycan binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       1.5   5.2e+03       3      34 ..     230     262 ..     229     265 .. 0.81
   2 ?   -0.4   0.0      0.38   1.4e+03      45      57 .]     279     291 ..     274     291 .. 0.84
   3 ?    7.2   0.0    0.0016       5.8      27      57 .]     316     346 ..     298     346 .. 0.78
   4 ?    0.7   0.0      0.17   6.1e+02      28      40 ..     836     848 ..     823     851 .. 0.87

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 1.5
                   HHHHHHHHHHHHTT--..SSSSSB--HHHHHHH CS
  PG_binding_1   3 edvkelqryLsrlGyl.sgpadgtfgpateeaV 34 
                   e vk+ q +L+ +  l +  adg   + te+a+
    EEA21619.1 230 ELVKQCQLALTIFDKLaPEYADGLLCDVTEKAI 262
                   679999999999977777789999999999998 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.38
                   -SSSBSHHHHHHH CS
  PG_binding_1  45 vtGildpaTlaal 57 
                    +Gil+  T+aal
    EEA21619.1 279 SDGILGVTTVAAL 291
                   6999999999997 PP

  == domain 3  score: 7.2 bits;  conditional E-value: 0.0016
                   -HHHHHHHHHHHHHTTST-SSSBSHHHHHHH CS
  PG_binding_1  27 gpateeaVkefQqffgLpvtGildpaTlaal 57 
                    +++++ V  fQ+ ++L  t +ld++Tl+ l
    EEA21619.1 316 LSGMKRGVGSFQKSQKLARTRRLDRDTLDRL 346
                   4789999*********************976 PP

  == domain 4  score: 0.7 bits;  conditional E-value: 0.17
                   HHHHHHHHHHHHH CS
  PG_binding_1  28 pateeaVkefQqf 40 
                   +++ee ++efQ++
    EEA21619.1 836 EDVEEGLQEFQRH 848
                   6789*******97 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   3.4   0.00061       2.2      45     103 ..     788     847 ..     752     853 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00061
      APG6_N  45 qdeeleeleeelek.lekeeeelleeLkelekereeleaelaaleeelealeeeeerfwr 103
                   e+++el+e+  + l +e ++l ee+k++e   ++l+ el+ le++ e++ee  ++f r
  EEA21619.1 788 RIEDIQELRERTNQvLGDEGSRLTEEMKKIELLGAKLDYELNVLESKIEDVEEGLQEFQR 847
                 4568888888877747788899*******************************9999876 PP

>> DUF4164  Domain of unknown function (DUF4164)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.2      0.26   9.4e+02      10      44 ..     335     370 ..     327     372 .. 0.80
   2 ?    9.2   0.9   0.00041       1.5      34      87 ..     806     860 ..     785     862 .. 0.83

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.26
     DUF4164  10 ltrLea.aldsLEkavdrrleaerkrdeleaeieal 44 
                 ++rL++  ld+L + +++ +++er  +++++++++l
  EEA21619.1 335 TRRLDRdTLDRLHRVSQKSTNSERWAGAVKSTVAEL 370
                 667764279999999999999999999999999877 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00041
     DUF4164  34 r.deleaeiealgedrsRLaeeLdqaearaarleevnrEvsrrLkaaietiravL 87 
                 + + l +e+++++   ++L+ eL   e + + +ee+ +E +r  +++ + ir++ 
  EEA21619.1 806 EgSRLTEEMKKIELLGAKLDYELNVLESKIEDVEEGLQEFQRHVDVVENRIRGLV 860
                 2577899999******************************************876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (881 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       567  (0.0316247); expected 358.6 (0.02)
Passed bias filter:                      470  (0.0262145); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.71u 0.29s 00:00:01.00 Elapsed: 00:00:00.46
# Mc/sec: 5786.45
//
Query:       EEA21620.1  [L=411]
Description: regulator of gluconeogenesis Rmd5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      1e-32  113.1   0.0    1.9e-32  112.2   0.0    1.5  1  CLTH          CTLH/CRA C-terminal to LisH motif domain
    1.1e-08   35.0   0.4    2.3e-08   33.9   0.4    1.6  1  zf-RING_UBOX  RING-type zinc-finger
     0.0003   20.3   0.2     0.0003   20.3   0.2    1.8  2  Rtf2          Rtf2 RING-finger
    0.00067   19.6   0.4     0.0011   18.8   0.4    1.4  1  zf-RING_5     zinc-RING finger domain
      0.001   19.4   0.7     0.0018   18.5   0.7    1.4  1  zf-RING_2     Ring finger domain
     0.0021   17.8   1.5     0.0045   16.8   1.5    1.6  1  zf-C3HC4_2    Zinc finger, C3HC4 type (RING finger)
     0.0067   16.3   1.3      0.013   15.4   1.3    1.4  1  Prok-RING_4   Prokaryotic RING finger family 4
     0.0093   15.8   1.2      0.018   14.9   1.2    1.4  1  zf-C3HC4      Zinc finger, C3HC4 type (RING finger)
  ------ inclusion threshold ------
      0.014   15.2   0.6      0.025   14.4   0.6    1.3  1  zf-C3HC4_3    Zinc finger, C3HC4 type (RING finger)
      0.093   12.9   1.2        0.2   11.9   1.2    1.6  1  zf-C3HC4_4    zinc finger of C3HC4-type, RING
       0.15   12.1   0.2       0.67   10.0   0.1    2.0  2  EPO_TPO       Erythropoietin/thrombopoietin


Domain annotation for each model (and alignments):
>> CLTH  CTLH/CRA C-terminal to LisH motif domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.2   0.0   1.2e-35   1.9e-32       2     147 ..     166     318 ..     165     319 .. 0.93

  Alignments for each domain:
  == domain 1  score: 112.2 bits;  conditional E-value: 1.2e-35
        CLTH   2 ikerqkIikli.legdlseaiewinenkpellesnsnLeFkLkllqfielirg.........ktkdieealeyarenlefendehlkelekamsLLafs 90 
                 ++++++I  ++ ++ +l +ai+w+ ++++ l+++ snLeF+L +lqf++l+ g         + +  ++aleyar+++  +   +lke+++++s++af 
  EEA21620.1 166 FTKMYHILRELrENSNLLPAIDWARDHRSVLESRGSNLEFELCRLQFVWLFHGgtklqyspsS-DGRQAALEYARQEFLTFTPRYLKEIQQLISAMAFW 263
                 7899************************************************98877777743.88************666666**************9 PP

        CLTH  91 dpeskelssplknlldp.srrekvakefnsailkllglskespLeillsaglsalktl 147
                 ++ +    sp+++++++   +++va+ f++++++llgls +spL i+ +ag++al+tl
  EEA21620.1 264 PNLD---ESPYRHIFNNpTAWSDVAHSFTREFCSLLGLSADSPLYIAATAGAIALPTL 318
                 9666...89********9**************************************98 PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.9   0.4   1.4e-11   2.3e-08       1      39 []     356     395 ..     356     395 .. 0.93

  Alignments for each domain:
  == domain 1  score: 33.9 bits;  conditional E-value: 1.4e-11
  zf-RING_UBOX   1 CpIClelft..dP.lvlpCGHtFCreClwelskslegafkCP 39 
                   Cp+++e+ t  +P +++pCGH++ +e l  ++ s++++fkCP
    EEA21620.1 356 CPVSKEQTTdqNPpMMMPCGHVIAQESL--QRISKGNKFKCP 395
                   *********99777667***********..7**********9 PP

>> Rtf2  Rtf2 RING-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   1.1       1.7   2.8e+03     100     100 ..      33      33 ..       3      88 .. 0.38
   2 !   20.3   0.2   1.8e-07    0.0003     113     160 ..     352     401 ..     347     410 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 1.7
        Rtf2 100 e 100
                 +
  EEA21620.1  33 K 33 
                 1 PP

  == domain 2  score: 20.3 bits;  conditional E-value: 1.8e-07
        Rtf2 113 apfiCpltglemngktkfvalrkCGcVfsekalkevk...sevClvCgkey 160
                 + f+Cp+++ +  +++   ++++CG+V++++ l+ +    + +C+ C  e 
  EEA21620.1 352 SIFVCPVSKEQTTDQNPP-MMMPCGHVIAQESLQRISkgnKFKCPYCPSES 401
                 57*********9998886.578**************6455556**997765 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.4   6.9e-07    0.0011       2      42 ..     356     397 ..     355     399 .. 0.92

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 6.9e-07
   zf-RING_5   2 CnkCfeklskeekfyltsCgHifCekClkkll.ekeavCpiC 42 
                 C++  e+++++ ++++++CgH++ ++ l++ + +++++Cp C
  EEA21620.1 356 CPVSKEQTTDQNPPMMMPCGHVIAQESLQRISkGNKFKCPYC 397
                 8888888999999******************99********* PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.7   1.1e-06    0.0018       3      43 ..     356     397 ..     354     398 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 1.1e-06
   zf-RING_2   3 CpICleelssadsvlllpCgHvfhreClerwlrssst..CPlC 43 
                 Cp+  e+ ++++ ++ +pCgHv+ +e l+r+  + ++  CP+C
  EEA21620.1 356 CPVSKEQTTDQNPPMMMPCGHVIAQESLQRIS-KGNKfkCPYC 397
                 77776677776667788*************65.444459**** PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   1.5   2.8e-06    0.0045      10      40 .]     366     397 ..     355     397 .. 0.83

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 2.8e-06
  zf-C3HC4_2  10 kdpsvvtpCgHvfCqkCilrsLeekn.eCPlC 40 
                 ++p ++ pCgHv  q+ ++r  + ++ +CP C
  EEA21620.1 366 QNPPMMMPCGHVIAQESLQRISKGNKfKCPYC 397
                 5788****************6566669***** PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   1.3   7.9e-06     0.013       6      40 ..     364     401 ..     355     406 .. 0.77

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 7.9e-06
  Prok-RING_4   6 eqekkailepCgHlvCkeCfdsk.dls..sCPlCqrri 40 
                  + ++ +++ pCgH++ +e ++   + +   CP C ++ 
   EEA21620.1 364 TDQNPPMMMPCGHVIAQESLQRIsKGNkfKCPYCPSES 401
                  44777899*************985333679****9875 PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   1.2   1.1e-05     0.018       1      41 []     356     397 ..     356     397 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.1e-05
                 -TTT-S--SS-E...E-TTS--B-CHHHHHHHHCTSSB--TTT CS
    zf-C3HC4   1 CpiCleeakepn..elleCkHsfCskCirkilksrkkvkCPlC 41 
                 Cp+ +e  +++n  ++++C+H + ++ +++i k  +k+kCP C
  EEA21620.1 356 CPVSKEQTTDQNppMMMPCGHVIAQESLQRISK-GNKFKCPYC 397
                 666666666666779******************.********9 PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.6   1.6e-05     0.025      15      45 ..     369     399 ..     354     402 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.6e-05
                 EEETTEEEEEE-HHHHHHHHH.TT-B-TTT-- CS
  zf-C3HC4_3  15 vvllpCgHlvlCeeCaekllk.rkkkCpiCrr 45 
                  +++pCgH+ + +e ++++ k +k kCp+C +
  EEA21620.1 369 PMMMPCGHV-IAQESLQRISKgNKFKCPYCPS 399
                 6899*****.99*******99*********76 PP

>> zf-C3HC4_4  zinc finger of C3HC4-type, RING
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   1.2   0.00012       0.2      11      42 .]     369     397 ..     356     397 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00012
  zf-C3HC4_4  11 PvsleCGhsfClsCisslqkepdgeqllCplC 42 
                 P+ ++CGh++ ++ +++++k +   ++ Cp C
  EEA21620.1 369 PMMMPCGHVIAQESLQRISKGN---KFKCPYC 397
                 9***********9999988877...699***9 PP

>> EPO_TPO  Erythropoietin/thrombopoietin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.1   0.00041      0.67      46      97 ..      10      61 ..       8      81 .. 0.83
   2 ?   -1.1   0.0         1   1.7e+03      78     118 ..     145     186 ..     140     199 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00041
     EPO_TPO 46 eewkkkeeeekaqevwqgltlLseavlkaqallanssqsslllqlhidkavs 97
                ++wk++++ +  ++v++++ lL++a  ++ a  +++s + + lq+ + ++  
  EEA21620.1 10 RAWKRMKAAKSINDVQATIDLLQKARDSIAADPTKASITLAKLQNPVKASFD 61
                58***********************999999999988888888887777665 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 1
     EPO_TPO  78 lanssqsslllqlhidkavsnlrSlrallrlLgtqe.svPda 118
                 +++   s++l q h d+  ++   +  +lr L+  +  +P  
  EEA21620.1 145 INENNTSTILDQIHSDRIREEFTKMYHILRELRENSnLLPAI 186
                 455555678889999999999999999999999888677765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (411 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1026  (0.0572257); expected 358.6 (0.02)
Passed bias filter:                      806  (0.0449551); expected 358.6 (0.02)
Passed Vit filter:                        87  (0.00485247); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.58u 0.31s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 2674.42
//
Query:       EEA21621.1  [L=301]
Description: regulator of gluconeogenesis Rmd5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.3e-33  113.8   0.0    9.2e-33  113.2   0.0    1.3  1  CLTH          CTLH/CRA C-terminal to LisH motif domain
    7.1e-09   35.5   0.4    1.5e-08   34.5   0.4    1.6  1  zf-RING_UBOX  RING-type zinc-finger
    0.00012   21.6   0.2    0.00019   20.9   0.2    1.2  1  Rtf2          Rtf2 RING-finger
    0.00043   20.2   0.4    0.00072   19.5   0.4    1.4  1  zf-RING_5     zinc-RING finger domain
    0.00064   20.0   0.7     0.0012   19.2   0.7    1.5  1  zf-RING_2     Ring finger domain
     0.0014   18.4   1.5     0.0029   17.4   1.5    1.6  1  zf-C3HC4_2    Zinc finger, C3HC4 type (RING finger)
     0.0042   16.9   1.3     0.0082   16.0   1.3    1.5  1  Prok-RING_4   Prokaryotic RING finger family 4
      0.006   16.4   1.2      0.011   15.5   1.2    1.5  1  zf-C3HC4      Zinc finger, C3HC4 type (RING finger)
     0.0092   15.8   0.6      0.016   15.0   0.6    1.3  1  zf-C3HC4_3    Zinc finger, C3HC4 type (RING finger)
  ------ inclusion threshold ------
      0.068   13.3   1.2       0.13   12.5   1.2    1.5  1  zf-C3HC4_4    zinc finger of C3HC4-type, RING


Domain annotation for each model (and alignments):
>> CLTH  CTLH/CRA C-terminal to LisH motif domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.2   0.0   5.1e-36   9.2e-33       2     147 ..      56     208 ..      55     209 .. 0.93

  Alignments for each domain:
  == domain 1  score: 113.2 bits;  conditional E-value: 5.1e-36
        CLTH   2 ikerqkIikli.legdlseaiewinenkpellesnsnLeFkLkllqfielirg.........ktkdieealeyarenlefendehlkelekamsLLafs 90 
                 ++++++I  ++ ++ +l +ai+w+ ++++ l+++ snLeF+L +lqf++l+ g         + +  ++aleyar+++  +   +lke+++++s++af 
  EEA21621.1  56 FTKMYHILRELrENSNLLPAIDWARDHRSVLESRGSNLEFELCRLQFVWLFHGgtklqyspsS-DGRQAALEYARQEFLTFTPRYLKEIQQLISAMAFW 153
                 7899************************************************98877777743.88************666666**************9 PP

        CLTH  91 dpeskelssplknlldp.srrekvakefnsailkllglskespLeillsaglsalktl 147
                 ++ +    sp+++++++   +++va+ f++++++llgls +spL i+ +ag++al+tl
  EEA21621.1 154 PNLD---ESPYRHIFNNpTAWSDVAHSFTREFCSLLGLSADSPLYIAATAGAIALPTL 208
                 9666...89********9**************************************98 PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.5   0.4   8.3e-12   1.5e-08       1      39 []     246     285 ..     246     285 .. 0.93

  Alignments for each domain:
  == domain 1  score: 34.5 bits;  conditional E-value: 8.3e-12
  zf-RING_UBOX   1 CpIClelft..dP.lvlpCGHtFCreClwelskslegafkCP 39 
                   Cp+++e+ t  +P +++pCGH++ +e l  ++ s++++fkCP
    EEA21621.1 246 CPVSKEQTTdqNPpMMMPCGHVIAQESL--QRISKGNKFKCP 285
                   *********99777667***********..7**********9 PP

>> Rtf2  Rtf2 RING-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.2     1e-07   0.00019     113     160 ..     242     291 ..     237     300 .. 0.81

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 1e-07
        Rtf2 113 apfiCpltglemngktkfvalrkCGcVfsekalkevk...sevClvCgkey 160
                 + f+Cp+++ +  +++   ++++CG+V++++ l+ +    + +C+ C  e 
  EEA21621.1 242 SIFVCPVSKEQTTDQNPP-MMMPCGHVIAQESLQRISkgnKFKCPYCPSES 291
                 57*********9998886.578**************6455556**997765 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.4     4e-07   0.00072       2      42 ..     246     287 ..     245     289 .. 0.92

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 4e-07
   zf-RING_5   2 CnkCfeklskeekfyltsCgHifCekClkkll.ekeavCpiC 42 
                 C++  e+++++ ++++++CgH++ ++ l++ + +++++Cp C
  EEA21621.1 246 CPVSKEQTTDQNPPMMMPCGHVIAQESLQRISkGNKFKCPYC 287
                 8888889999999******************99********* PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   0.7   6.6e-07    0.0012       3      43 ..     246     287 ..     244     288 .. 0.77

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 6.6e-07
   zf-RING_2   3 CpICleelssadsvlllpCgHvfhreClerwlrssst..CPlC 43 
                 Cp+  e+ ++++ ++ +pCgHv+ +e l+r+  + ++  CP+C
  EEA21621.1 246 CPVSKEQTTDQNPPMMMPCGHVIAQESLQRIS-KGNKfkCPYC 287
                 77776777776667788*************65.444459**** PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   1.5   1.6e-06    0.0029      10      40 .]     256     287 ..     245     287 .. 0.83

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 1.6e-06
  zf-C3HC4_2  10 kdpsvvtpCgHvfCqkCilrsLeekn.eCPlC 40 
                 ++p ++ pCgHv  q+ ++r  + ++ +CP C
  EEA21621.1 256 QNPPMMMPCGHVIAQESLQRISKGNKfKCPYC 287
                 5788****************6566669***** PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   1.3   4.6e-06    0.0082       6      40 ..     254     291 ..     245     296 .. 0.77

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 4.6e-06
  Prok-RING_4   6 eqekkailepCgHlvCkeCfdsk.dls..sCPlCqrri 40 
                  + ++ +++ pCgH++ +e ++   + +   CP C ++ 
   EEA21621.1 254 TDQNPPMMMPCGHVIAQESLQRIsKGNkfKCPYCPSES 291
                  44777899*************985333679****9875 PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   1.2   6.4e-06     0.011       1      41 []     246     287 ..     246     287 .. 0.86

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 6.4e-06
                 -TTT-S--SS-E...E-TTS--B-CHHHHHHHHCTSSB--TTT CS
    zf-C3HC4   1 CpiCleeakepn..elleCkHsfCskCirkilksrkkvkCPlC 41 
                 Cp+ +e  +++n  ++++C+H + ++ +++i k  +k+kCP C
  EEA21621.1 246 CPVSKEQTTDQNppMMMPCGHVIAQESLQRISK-GNKFKCPYC 287
                 666666666666779******************.********9 PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.6   9.2e-06     0.016      15      45 ..     259     289 ..     244     292 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 9.2e-06
                 EEETTEEEEEE-HHHHHHHHH.TT-B-TTT-- CS
  zf-C3HC4_3  15 vvllpCgHlvlCeeCaekllk.rkkkCpiCrr 45 
                  +++pCgH+ + +e ++++ k +k kCp+C +
  EEA21621.1 259 PMMMPCGHV-IAQESLQRISKgNKFKCPYCPS 289
                 6899*****.99*******99*********76 PP

>> zf-C3HC4_4  zinc finger of C3HC4-type, RING
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   1.2   7.2e-05      0.13      11      42 .]     259     287 ..     246     287 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 7.2e-05
  zf-C3HC4_4  11 PvsleCGhsfClsCisslqkepdgeqllCplC 42 
                 P+ ++CGh++ ++ +++++k +   ++ Cp C
  EEA21621.1 259 PMMMPCGHVIAQESLQRISKGN---KFKCPYC 287
                 9***********9999988877...699***9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (301 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       604  (0.0336884); expected 358.6 (0.02)
Passed bias filter:                      539  (0.030063); expected 358.6 (0.02)
Passed Vit filter:                        72  (0.00401584); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 1991.24
//
Query:       EEA21622.1  [L=286]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.8e-07   29.3   0.0    3.5e-06   27.2   0.0    2.0  2  BTB       BTB/POZ domain
  ------ inclusion threshold ------
      0.014   15.5   0.0      0.033   14.4   0.0    1.6  1  Skp1_POZ  Skp1 family, tetramerisation domain


Domain annotation for each model (and alignments):
>> BTB  BTB/POZ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.2   0.0   3.9e-10   3.5e-06      13      75 ..      71     132 ..      61     143 .. 0.87
   2 ?   -1.7   0.0      0.36   3.3e+03      20      35 ..     226     241 ..     223     257 .. 0.79

  Alignments for each domain:
  == domain 1  score: 27.2 bits;  conditional E-value: 3.9e-10
                 EEEEETT.TEEEEE-HHHHHHH-HHHHHHHTSTTTTTCCCEEEEETTSGHHHHHHHHHHHHHSE CS
         BTB  13 vtlvvgd.gkefkahkavLaarSpyFkalftskeieessvseielddvepeafealLefiYtge 75 
                 vt+ vg+ ++ f ah  vL+  Sp+F +   ++ + ++++++i l+d +pe++ ++Le++Y g 
  EEA21622.1  71 VTICVGKdQRLFAAHEDVLS-LSPVFADCCREQ-FLQAHNKQISLPDEQPEILSSILEYLYKGD 132
                 78888885667777777776.69**********.99999999*******************986 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.36
                 TEEEEE-HHHHHHH-H CS
         BTB  20 gkefkahkavLaarSp 35 
                 +++++ah + L  rS 
  EEA21622.1 226 DSQLRAHYLALIIRSR 241
                 5789999999999995 PP

>> Skp1_POZ  Skp1 family, tetramerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   3.7e-06     0.033       8      60 ..      77     130 ..      70     132 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 3.7e-06
                 TTSCEEEEEHHHHTTSHHHHHHH.HCTCCCGTTCEEETTS-HHHHHHHHHHHHH CS
    Skp1_POZ   8 sDgesfeveeavakkSktikhmi.edlgdddkpriplpnvtskiLekvieYckh 60 
                 +D+  f++ e+v+  S+++++   e+  +  +++i lp  + +iL+ ++eY+++
  EEA21622.1  77 KDQRLFAAHEDVLSLSPVFADCCrEQFLQAHNKQISLPDEQPEILSSILEYLYK 130
                 89999**************998835555555589*****************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (286 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       464  (0.0258799); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2047.65
//
Query:       EEA21623.1  [L=458]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-08   35.6   0.0    2.3e-08   34.5   0.0    1.6  1  PCI           PCI domain
  ------ inclusion threshold ------
      0.075   11.5   0.0       0.12   10.8   0.0    1.2  1  Cohesin_load  Cohesin loading factor
       0.14   12.4   0.1       0.42   10.8   0.1    1.9  1  TPR_2         Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> PCI  PCI domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.5   0.0   3.9e-12   2.3e-08       4     105 .]     323     449 ..     320     449 .. 0.95

  Alignments for each domain:
  == domain 1  score: 34.5 bits;  conditional E-value: 3.9e-12
                 HHHHHHHHHTSHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHH................CESEEEHHHHHHHHTSSH..........HH CS
         PCI   4 sdllkalrsgnlsgfseelkdleeelladdglaqllesLekkvrerllrqvsk................iyssislerlaklldlsv..........de 76 
                 + l  ++r gnl gf+ ++    ++ + ++ ++  le+ ++ + ++l+r+v+                   ++i+l ++a +l + +          de
  EEA21623.1 323 RPLCDCIRQGNLGGFDAAMSAG-ADEFVKRRIYLPLERGRDLALRNLFRKVFIaggfepaaanadsvpiRRTRIPLTEFAAALRIGNqadekvridmDE 420
                 678999****************.777777999999*********************************999**************************** PP

                 HHHHHHHHHHTTSSSEEEETTTTEEEECS CS
         PCI  77 vEkilvklIrdgeirakidqesgivvfkk 105
                 vE++l+++I+++ ++++i++e  +vv++k
  EEA21623.1 421 VECLLANMIYKNMMKGYISRERATVVLSK 449
                 *************************9986 PP

>> Cohesin_load  Cohesin loading factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   1.9e-05      0.12      75     106 ..     264     295 ..     244     312 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 1.9e-05
  Cohesin_load  75 enideAeeylskailiaeknrlidlkfvcqfL 106
                   en++eAee+l++a+l+++ + l + ++   +L
    EEA21623.1 264 ENYKEAEEHLTQAWLMCKTDALKNKELILTYL 295
                   8*****************99999988888777 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.1   7.1e-05      0.42       4      27 ..     253     276 ..     250     276 .. 0.93

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 7.1e-05
       TPR_2   4 lynlGlayyklgdyeeAleafekA 27 
                 +y+ Gl+ +   +y+eA+e++ +A
  EEA21623.1 253 NYYVGLINFLEENYKEAEEHLTQA 276
                 799******************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (458 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       398  (0.0221987); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.47u 0.23s 00:00:00.70 Elapsed: 00:00:00.37
# Mc/sec: 3675.90
//
Query:       EEA21624.1  [L=174]
Description: Ribosomal L18ae protein family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.1e-55  183.9   0.1    1.1e-54  183.6   0.1    1.1  1  Ribosomal_L18A  Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A


Domain annotation for each model (and alignments):
>> Ribosomal_L18A  Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  183.6   0.1   6.3e-59   1.1e-54       1     120 [.       4     126 ..       4     127 .. 0.99

  Alignments for each domain:
  == domain 1  score: 183.6 bits;  conditional E-value: 6.3e-59
                     -EEEEEEEEEEET....................................................................TEEEEEEEEEEESS CS
  Ribosomal_L18A   1 lkeYeVvGrklpsekepepkvyrmrifapnevvak...wyflkklkkvkkanGeilavkkieekkptkvknygiwlrydsrsgthnfykeyrdlt 92 
                     l+eY+V+Gr+lp+e++p+pk+yrmrifapn+vvak   wyfl+klkkvkkanGei++++ i+ek+ptkvkn+giwlrydsrsgthn+yke+r+l+
      EEA21624.1   4 LNEYQVIGRHLPTEANPTPKLYRMRIFAPNTVVAKsrfWYFLTKLKKVKKANGEIVSLNVISEKRPTKVKNFGIWLRYDSRSGTHNMYKEFRELS 98 
                     589******************************************************************************************** PP

                     HHHHHHHHHHHHHHHS---GGGEEEEEE CS
  Ribosomal_L18A  93 eegaveqvYselgsrhrakrssIqIekv 120
                     +++av+ +Y+++++rhra+  sI+I++v
      EEA21624.1  99 RTDAVDSLYQDMAARHRARFGSIHILRV 126
                     **************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (174 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       358  (0.0199677); expected 358.6 (0.02)
Passed bias filter:                      300  (0.0167327); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.25s 00:00:00.67 Elapsed: 00:00:00.41
# Mc/sec: 1267.29
//
Query:       EEA21625.1  [L=148]
Description: Ribosomal L18ae protein family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.3e-44  150.4   0.3    2.9e-44  150.0   0.3    1.1  1  Ribosomal_L18A  Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A


Domain annotation for each model (and alignments):
>> Ribosomal_L18A  Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  150.0   0.3   1.6e-48   2.9e-44      24     120 ..       1     100 [.       1     101 [. 0.99

  Alignments for each domain:
  == domain 1  score: 150.0 bits;  conditional E-value: 1.6e-48
                     ..........................................................TEEEEEEEEEEESSHHHHHHHHHHHHHHHS---GGGE CS
  Ribosomal_L18A  24 mrifapnevvak...wyflkklkkvkkanGeilavkkieekkptkvknygiwlrydsrsgthnfykeyrdlteegaveqvYselgsrhrakrssI 115
                     mrifapn+vvak   wyfl+klkkvkkanGei++++ i+ek+ptkvkn+giwlrydsrsgthn+yke+r+l++++av+ +Y+++++rhra+  sI
      EEA21625.1   1 MRIFAPNTVVAKsrfWYFLTKLKKVKKANGEIVSLNVISEKRPTKVKNFGIWLRYDSRSGTHNMYKEFRELSRTDAVDSLYQDMAARHRARFGSI 95 
                     9********************************************************************************************** PP

                     EEEEE CS
  Ribosomal_L18A 116 qIekv 120
                     +I++v
      EEA21625.1  96 HILRV 100
                     ***98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (148 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       439  (0.0244855); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.37u 0.27s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1113.07
//
Query:       EEA21626.1  [L=323]
Description: NADH-cytochrome b5 reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      4e-34  117.5   0.0    7.4e-34  116.7   0.0    1.5  1  NAD_binding_1  Oxidoreductase NAD-binding domain
    4.5e-24   84.7   0.0    1.5e-23   83.0   0.0    1.9  2  FAD_binding_6  Oxidoreductase FAD-binding domain
    1.3e-09   38.3   0.0      9e-05   22.6   0.0    2.4  2  NAD_binding_6  Ferric reductase NAD binding domain


Domain annotation for each model (and alignments):
>> NAD_binding_1  Oxidoreductase NAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.7   0.0   1.2e-37   7.4e-34       1     108 [.     186     294 ..     186     295 .. 0.98

  Alignments for each domain:
  == domain 1  score: 116.7 bits;  conditional E-value: 1.2e-37
                    EEEEGGGGHHHHHHHHHHHHHCTTCSEEEEEEEESSGCGSTTHHHHHHHHHHCTTEEEEEEEESSCTTTSSSEESSHHHHHHHHHHH.HSSTTEEE CS
  NAD_binding_1   1 miagGtGiaPvrsvlraileeakdktkvvlvyGnrteedllyreeleelakklpgrlkvvavvsreeagweggkgrvqdalleells.lkkeethv 95 
                    +iagGtGi+P+++++rai+++++dktkv+lvyGn te+d+l+++el+ l++++p+r+k ++ +++++++w+gg g+v+++ll+++l+  k+e+  v
     EEA21626.1 186 LIAGGTGITPMYQLIRAIFKNPEDKTKVTLVYGNVTEDDILLKKELQHLENTYPQRFKTFYLLDKPPKEWTGGSGYVTKELLKTVLPePKEENIKV 281
                    7**************************************************************************************9899***** PP

                    EEECSHHHHHHHH CS
  NAD_binding_1  96 yvCGppgMikavr 108
                    +vCGppgM ka++
     EEA21626.1 282 FVCGPPGMYKAIS 294
                    *********9975 PP

>> FAD_binding_6  Oxidoreductase FAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0       1.5   8.9e+03      43      62 ..      12      30 ..       6      34 .. 0.66
   2 !   83.0   0.0   2.4e-27   1.5e-23       2      96 ..      78     173 ..      77     176 .. 0.96

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 1.5
                   TTCCEEEEEE.BSSTTECCE CS
  FAD_binding_6 43 kgeaviRsYtpissenekGe 62
                   + ++  R+Y+ + +++++++
     EEA21626.1 12 PARQSFRKYS-TEAPTKSNT 30
                   5567789999.666666665 PP

  == domain 2  score: 83.0 bits;  conditional E-value: 2.4e-27
                    EEEEEEEECCTTEEEEEEEESTTTS-----TT-EEEEEEC.ETTCCEEEEEE.BSSTTECCEEEEEEE--TT-HHHHHHHCS-TT-EEEEEEEE-S CS
  FAD_binding_6   2 lkltekeevsedtrifrfklpsekqklglpvGqhvflrlk.ikgeaviRsYtpissenekGelellvkvypgGkmsqaLdelkigdtleikGPlGk 96 
                    lkl++ e vs+dt+++rf++++++++ gl v++ +  ++   +g+ ++R+Ytpis+e++ G+l+l+vk+yp+G+m++++d++ +g++l++kGPl k
     EEA21626.1  78 LKLADIEVVSPDTKRYRFEFEDKEAVSGLHVASALLTKYApPEGKPILRPYTPISDEDTPGHLDLIVKHYPNGAMTSHMDSMSVGQSLDFKGPLPK 173
                    6899*******************************99998799**************************************************866 PP

>> NAD_binding_6  Ferric reductase NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.6   0.0   1.5e-08     9e-05       1      63 [.     181     238 ..     181     248 .. 0.79
   2 !   13.3   0.0   1.2e-05     0.069     122     151 ..     264     293 ..     263     295 .. 0.89

  Alignments for each domain:
  == domain 1  score: 22.6 bits;  conditional E-value: 1.5e-08
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  NAD_binding_6   1 yenvllvagGiGitpfisilkdllkkskkealktkkikliwvvressslewfkdvLneleeek 63 
                    ++++ l+agG+Gitp++ +++ ++k+ +    +++k++l+  +  ++++  +k+ L+ le++ 
     EEA21626.1 181 HTHIALIAGGTGITPMYQLIRAIFKNPE----DKTKVTLVYGNVTEDDIL-LKKELQHLENTY 238
                    6789***********************9....888888888777777764.344666666655 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 1.2e-05
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  NAD_binding_6 122 kevlkdiaskhknssvgvfvCGppklvkev 151
                    ke+lk++  + k++++ vfvCGpp++ k +
     EEA21626.1 264 KELLKTVLPEPKEENIKVFVCGPPGMYKAI 293
                    68899999999***************9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (323 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       490  (0.02733); expected 358.6 (0.02)
Passed bias filter:                      473  (0.0263818); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2283.99
//
Query:       EEA21627.1  [L=273]
Description: NADH-cytochrome b5 reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.3e-34  117.8   0.0    5.1e-34  117.2   0.0    1.3  1  NAD_binding_1  Oxidoreductase NAD-binding domain
    4.9e-24   84.6   0.0      1e-23   83.5   0.0    1.6  1  FAD_binding_6  Oxidoreductase FAD-binding domain
    9.2e-10   38.8   0.0    6.9e-05   23.0   0.0    2.3  2  NAD_binding_6  Ferric reductase NAD binding domain


Domain annotation for each model (and alignments):
>> NAD_binding_1  Oxidoreductase NAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.2   0.0   8.6e-38   5.1e-34       1     108 [.     136     244 ..     136     245 .. 0.98

  Alignments for each domain:
  == domain 1  score: 117.2 bits;  conditional E-value: 8.6e-38
                    EEEEGGGGHHHHHHHHHHHHHCTTCSEEEEEEEESSGCGSTTHHHHHHHHHHCTTEEEEEEEESSCTTTSSSEESSHHHHHHHHHHH.HSSTTEEE CS
  NAD_binding_1   1 miagGtGiaPvrsvlraileeakdktkvvlvyGnrteedllyreeleelakklpgrlkvvavvsreeagweggkgrvqdalleells.lkkeethv 95 
                    +iagGtGi+P+++++rai+++++dktkv+lvyGn te+d+l+++el+ l++++p+r+k ++ +++++++w+gg g+v+++ll+++l+  k+e+  v
     EEA21627.1 136 LIAGGTGITPMYQLIRAIFKNPEDKTKVTLVYGNVTEDDILLKKELQHLENTYPQRFKTFYLLDKPPKEWTGGSGYVTKELLKTVLPePKEENIKV 231
                    7**************************************************************************************9899***** PP

                    EEECSHHHHHHHH CS
  NAD_binding_1  96 yvCGppgMikavr 108
                    +vCGppgM ka++
     EEA21627.1 232 FVCGPPGMYKAIS 244
                    *********9975 PP

>> FAD_binding_6  Oxidoreductase FAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.5   0.0   1.7e-27     1e-23       2      96 ..      28     123 ..      27     126 .. 0.96

  Alignments for each domain:
  == domain 1  score: 83.5 bits;  conditional E-value: 1.7e-27
                    EEEEEEEECCTTEEEEEEEESTTTS-----TT-EEEEEEC.ETTCCEEEEEE.BSSTTECCEEEEEEE--TT-HHHHHHHCS-TT-EEEEEEEE-S CS
  FAD_binding_6   2 lkltekeevsedtrifrfklpsekqklglpvGqhvflrlk.ikgeaviRsYtpissenekGelellvkvypgGkmsqaLdelkigdtleikGPlGk 96 
                    lkl++ e vs+dt+++rf++++++++ gl v++ +  ++   +g+ ++R+Ytpis+e++ G+l+l+vk+yp+G+m++++d++ +g++l++kGPl k
     EEA21627.1  28 LKLADIEVVSPDTKRYRFEFEDKEAVSGLHVASALLTKYApPEGKPILRPYTPISDEDTPGHLDLIVKHYPNGAMTSHMDSMSVGQSLDFKGPLPK 123
                    6899*******************************99998799**************************************************866 PP

>> NAD_binding_6  Ferric reductase NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.0   0.0   1.2e-08   6.9e-05       1      63 [.     131     188 ..     131     198 .. 0.79
   2 !   13.6   0.0   9.2e-06     0.055     122     151 ..     214     243 ..     213     245 .. 0.89

  Alignments for each domain:
  == domain 1  score: 23.0 bits;  conditional E-value: 1.2e-08
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  NAD_binding_6   1 yenvllvagGiGitpfisilkdllkkskkealktkkikliwvvressslewfkdvLneleeek 63 
                    ++++ l+agG+Gitp++ +++ ++k+ +    +++k++l+  +  ++++  +k+ L+ le++ 
     EEA21627.1 131 HTHIALIAGGTGITPMYQLIRAIFKNPE----DKTKVTLVYGNVTEDDIL-LKKELQHLENTY 188
                    6789***********************9....888888888777777774.344666666655 PP

  == domain 2  score: 13.6 bits;  conditional E-value: 9.2e-06
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  NAD_binding_6 122 kevlkdiaskhknssvgvfvCGppklvkev 151
                    ke+lk++  + k++++ vfvCGpp++ k +
     EEA21627.1 214 KELLKTVLPEPKEENIKVFVCGPPGMYKAI 243
                    68899999999***************9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (273 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       300  (0.0167327); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.24s 00:00:00.70 Elapsed: 00:00:00.41
# Mc/sec: 1999.31
//
Query:       EEA21628.1  [L=304]
Description: HMG box protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-10   41.7   1.0    2.7e-10   40.5   1.0    1.7  1  HMG_box          HMG (high mobility group) box
    1.3e-05   25.7   0.4    3.9e-05   24.2   0.4    1.9  1  HMG_box_2        HMG-box domain
  ------ inclusion threshold ------
       0.29   10.4   5.5       0.63    9.3   5.5    1.5  1  NOA36            NOA36 protein
       0.74   10.0   5.9        2.1    8.6   5.9    1.8  1  Inhibitor_I53    Thrombin inhibitor Madanin
       0.89    7.8  11.3        1.3    7.3  11.3    1.2  1  CDC45            CDC45-like protein
        4.7    8.2   0.0        4.7    8.2   0.0    3.1  2  GEN1_C           Holliday junction resolvase Gen1 C-terminal 
        4.8    7.5  12.9         25    5.2  12.2    2.4  2  DUF4611          Domain of unknown function (DUF4611)
        8.3    4.4   9.5         13    3.7   9.5    1.2  1  DNA_pol_phi      DNA polymerase phi
        9.9    4.8   9.4         14    4.3   9.4    1.2  1  Presenilin       Presenilin


Domain annotation for each model (and alignments):
>> HMG_box  HMG (high mobility group) box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.5   1.0   1.3e-13   2.7e-10       1      69 []     108     177 ..     108     177 .. 0.97

  Alignments for each domain:
  == domain 1  score: 40.5 bits;  conditional E-value: 1.3e-13
                 --SS--HHHHHHHHHHHHHHHH.STTS-HHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
     HMG_box   1 pkRplsafflfskeqraklkae.nPelknaeiskklgekWkalseeeKkkYeekaekekaryekekpeyk 69 
                 pkR+l+ +fl+++++r  ++ e  P++k ++++ +   +W ++s eeK+ +++ ++   a y++++++yk
  EEA21628.1 108 PKRALTPYFLYMQHNRSLIANElGPDAKPKDVADEGTIRWANMSIEEKEVWKKLYNDNLAVYRAKMKAYK 177
                 8******************98857*********************************************8 PP

>> HMG_box_2  HMG-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.2   0.4   1.9e-08   3.9e-05       1      71 [.     105     175 ..     105     177 .. 0.88

  Alignments for each domain:
  == domain 1  score: 24.2 bits;  conditional E-value: 1.9e-08
                 ---.-SS--HHHHHHHTTHHHHHHHT---SSHHHHTGGGHHHHHHS-HHHHHHHHHHHHHHHHHHHH-SS- CS
   HMG_box_2   1 pkkpkaarnAYalfvqemipelkrkGnpviglaevsklcsekWkalseeeKekYeekAkedkkrydrealt 71 
                 p+ pk+a   Y+l++q  +  + ++  p ++ ++v  +   +W+++s eeKe +++  +   + y++ ++ 
  EEA21628.1 105 PNAPKRALTPYFLYMQHNRSLIANELGPDAKPKDVADEGTIRWANMSIEEKEVWKKLYNDNLAVYRAKMKA 175
                 789*******************999889************************9988777666666666665 PP

>> NOA36  NOA36 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   5.5   0.00032      0.63     246     289 ..     184     225 ..     161     239 .. 0.57

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00032
       NOA36 246 dddddeedsdydaylkalasgddeddegdedddddddeedddee 289
                 +dd+ ++ds+ ++     a++++ ++e+d+d dd+d++e+  +e
  EEA21628.1 184 EDDNAKADSQLQQS--VAAAEAEAEEETDSDSDDEDEDEESADE 225
                 44444444444443..3344445555555555555544444443 PP

>> Inhibitor_I53  Thrombin inhibitor Madanin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   5.9    0.0011       2.1      20      71 ..     182     236 ..     168     243 .. 0.61

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0011
                    XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------SS--...-----TTS---- CS
  Inhibitor_I53  20 yPerdsakdGnqekerallvkvqersdvdadydeydedgt...tptpdPtaptar 71 
                     Pe d ak   q ++     +     ++d+d d+ ded+     p+ +Pt p + 
     EEA21628.1 182 IPEDDNAKADSQLQQSVAAAEAEAEEETDSDSDDEDEDEEsadEPAKEPTPPPSN 236
                    69******77776665555555444444555555544443011466677766554 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3  11.3   0.00063       1.3     112     209 ..     190     291 ..     148     302 .. 0.42

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.00063
       CDC45 112 ieeeleeereayealeeeeesdeedeeeeeeddddeeeeeeeeedeedeeedeeeskkkrksksdeeee.sddddersrkrrrse.............p 196
                  +++l+++  a ea  eee           ++d+d+e+e+ee+ de  +e +   s+k+r++ ++   +  + ++ +++k++  +             p
  EEA21628.1 190 ADSQLQQSVAAAEAEAEEET----------DSDSDDEDEDEESADEPAKEPTPPPSNKRRRAGAKPPASpVAAKKASPEKKKAAQpaqpaptpakkdtP 278
                 23333333332222222222..........222222222222222222222222222222222222222322333333333333345555555555543 PP

       CDC45 197 sakklrrqlkker 209
                 s+k+++  ++ +r
  EEA21628.1 279 SRKTVNAASEGKR 291
                 3333333322222 PP

>> GEN1_C  Holliday junction resolvase Gen1 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   0.0    0.0024       4.7      60      87 ..      87     114 ..      64     128 .. 0.78
   2 ?   -7.4  20.6         9   1.8e+04      30      63 ..     198     250 ..     184     300 .. 0.59

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0024
      GEN1_C  60 eeeeeasakkkrkkkpydPseperiWip 87 
                 e++ e+ +kkkrk++p dP++p+r+  p
  EEA21628.1  87 EAKVETGEKKKRKRAPPDPNAPKRALTP 114
                 44478999***************98766 PP

  == domain 2  score: -7.4 bits;  conditional E-value: 9
      GEN1_C  30 Vaidlsgeegkreepagreglaededdedeeee...................e 63 
                 Va ++++ e++ ++++++e+++e++ de  +e+                    
  EEA21628.1 198 VAAAEAEAEEETDSDSDDEDEDEESADEPAKEPtpppsnkrrragakppaspV 250
                 33333333333333333333333333333222235544444444444444441 PP

>> DUF4611  Domain of unknown function (DUF4611)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.75   1.5e+03      17      45 ..      14      42 ..       4      49 .. 0.74
   2 ?    5.2  12.2     0.013        25      49      93 ..     193     238 ..     184     241 .. 0.70

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.75
     DUF4611 17 vkceapgeadrlk.sllsgvaqlreevsel 45
                v+++ + +  r++ + ++g+a l+  vs+l
  EEA21628.1 14 VSVNVN-DFTRFRdQFIVGLAALQSAVSDL 42
                566666.45666636899***999999986 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.013
     DUF4611  49 lveqeaqddvaaagdeeeegededdeeeekniknktksd.ePpaKr 93 
                 + +q  +   a+a++e+++++d++de+ee+  +  ++    P+ Kr
  EEA21628.1 193 QLQQSVAAAEAEAEEETDSDSDDEDEDEESADEPAKEPTpPPSNKR 238
                 4566666677888888888888888888887666666663555666 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   9.5    0.0066        13     679     716 ..     186     223 ..     176     233 .. 0.46

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.0066
  DNA_pol_phi 679 ddedvdeidelreklaealgesg..ededdddsdsDedmd 716
                  d++++d   +l++++a+a  e +   d+d+dd+d+De+  
   EEA21628.1 186 DNAKADS--QLQQSVAAAEAEAEeeTDSDSDDEDEDEESA 223
                  3333333..4444444444444422222222222223222 PP

>> Presenilin  Presenilin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   9.4    0.0071        14     215     306 ..     168     288 ..     157     303 .. 0.39

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.0071
  Presenilin 215 iYsatvvvlaaeek..kaevaeseeeeeaekkkeeasesskeeeseeesseksaqsse..............................seeeseeesse 281
                 +Y a++++ +a     ++++a+++++ +++ +++ea+ +++++++++++ e+++++ +                                 + e+++++
  EEA21628.1 168 VYRAKMKAYKAGLPipEDDNAKADSQLQQSVAAAEAEAEEETDSDSDDEDEDEESA-DepakeptpppsnkrrragakppaspvaakkA--SPEKKKAA 263
                 56666666655544432222222222222222222222222222222122222222.12445566788777777888888777766431..22222222 PP

  Presenilin 282 aessaeesseekeseessesseeee 306
                 ++++++ + ++k++ ++++ ++++e
  EEA21628.1 264 QPAQPAPTPAKKDTPSRKTVNAASE 288
                 2222222222222222222222221 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (304 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1438  (0.0802053); expected 358.6 (0.02)
Passed bias filter:                      618  (0.0344693); expected 358.6 (0.02)
Passed Vit filter:                       102  (0.00568911); expected 17.9 (0.001)
Passed Fwd filter:                        30  (0.00167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.70u 0.30s 00:00:01.00 Elapsed: 00:00:00.48
# Mc/sec: 1903.51
//
Query:       EEA21629.1  [L=836]
Description: urease Ure [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.2e-77  259.0   0.6    1.5e-76  258.0   0.6    1.5  1  Amidohydro_1  Amidohydrolase family
    1.3e-56  190.1   1.1    3.1e-56  188.9   1.1    1.7  1  Urease_alpha  Urease alpha-subunit, N-terminal domain
    1.8e-41  140.1   0.2    1.1e-40  137.5   0.0    2.1  2  Urease_beta   Urease beta subunit
    2.3e-39  133.7   0.4    2.1e-38  130.6   0.2    2.3  2  Urease_gamma  Urease, gamma subunit
    8.7e-10   38.7   0.1    0.00017   21.2   0.0    2.3  2  Amidohydro_3  Amidohydrolase family
  ------ inclusion threshold ------
        0.2   11.4   0.0       0.36   10.6   0.0    1.4  1  Amidohydro_2  Amidohydrolase


Domain annotation for each model (and alignments):
>> Amidohydro_1  Amidohydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  258.0   0.6   4.9e-80   1.5e-76       1     339 [.     396     725 ..     396     734 .. 0.98

  Alignments for each domain:
  == domain 1  score: 258.0 bits;  conditional E-value: 4.9e-80
                   EEEE-EEEEEEECETTECSSSGHHHHHSTTHHHHHHHHHHHHHHHHTTEEEEEEEEHSSTH....HHHHHHHHHHTSSSEEEEEEESSEGGSGCCCS CS
  Amidohydro_1   1 ivlPGlIDaHvHleqsllrgatledwlvppetaaealesgiktalksGtttvadmgattst....giealleaaeelplglrilggkvsldrgsaet 93 
                   iv++G+ D+H+H+              ++p+++ ea+ sgi+t+l++Gt++  +++att+t    +++ +++a+++lp++++i g+      g+++ 
    EEA21629.1 396 IVTAGGFDTHIHF--------------ICPQQINEAISSGITTMLGGGTGPSTGSNATTCTpgptHMRQMIQACDSLPVNVGITGK------GNDSG 472
                   79***********..............***********************************************************......***** PP

                   HHHHHHHHHHHHHHHHHHCTTTCEEEEEEECGTCCSHHHHHHHHHHHHHHHTTEEEEEE..TSSCHHHHHHHHHHTTTEEEETTTTSTCCHHTTTHC CS
  Amidohydro_1  94 skasreklkagaaetikgkadgvvkvalapheapafsdeelkealkeakkrdlpvaiHa..letkgevedaeaafgetiehgthlevaeslglldei 188
                    + +re+ +aga             ++++ he+++ ++++++ +l+++++ d++ +iH+  l+++g+ve++++ f+++++h++h+e+a++++++d+i
    EEA21629.1 473 VESLREQAIAGA-------------AGMKLHEDWGSTPAAIDTCLEVCDEFDIQCMIHTdtLNESGFVEQTIQSFKNRTIHTYHTEGAGGGHAPDII 556
                   ************.............************************************************************************ PP

                   CEEEHCTCEEE...HH...HHHHHHHHHHHHCEE.........HHHHHHHHSEHHHHHHHHHHHH.TSCEEEEEECTTSSCCGGHHHH...HHHHHH CS
  Amidohydro_1 189 klilahgvhlt...pt...eaellkerlkeagva.........hcpfsnsilrsgrealrkalde.GvkvglgtDgaasgnslnllee...lrlalk 266
                    ++ + +v+++   pt   ++++l+e+l++ +v+         +++f++s++r +++a++++l++ G+++++++D++a+g++++++ +   ++++ k
    EEA21629.1 557 SVVEHPNVLPSstnPTrpfTLNTLDEHLDMLMVChhlsknipeDVAFAESRIRGETIAAEDVLHDlGAISMMSSDSQAMGRCGEVILRtwnTAHKNK 653
                   ***********76655999********************************************************************99******** PP

                   HHHHCCTT...TTHCHCHHHHHHHHHTHHHHHHTT-TTTSSSS-TTSB--EEEECCCTCGGGTTTCTSEEEEEEEE CS
  Amidohydro_1 267 lqrgllye...deegglslkealrmaTingAkalglddkvGsievGkdADlvvvdldilaafvglkkdgnvkkviv 339
                    qrg+l e    +++++++k++++++Tin+A+a g+ + +Gs+evGk ADlv++    +++ +g+k++  vk++++
    EEA21629.1 654 EQRGVLPEdegTGADNFRVKRYISKYTINPAIAQGMVHLIGSVEVGKLADLVLW----TPDNFGTKPKLVVKGGMI 725
                   ********999889****************************************....****************98 PP

>> Urease_alpha  Urease alpha-subunit, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  188.9   1.1     1e-59   3.1e-56       2     121 .]     271     390 ..     270     390 .. 0.99

  Alignments for each domain:
  == domain 1  score: 188.9 bits;  conditional E-value: 1e-59
  Urease_alpha   2 klsreeyaelyGptvgDrvrLadtellievekDltvyGeevkfGggkviRdgmgqssaakeeealDlvitnavilDatgivkadigikdgrivaiGk 98 
                   +++re+y++++Gpt+gD vrL+ t+l+++vekDlt+yG+e++fGggk++R+gmgqss + ++e++D+v+tna+i+D++gi+kadigikdg iv+iGk
    EEA21629.1 271 SMEREAYVRMFGPTTGDLVRLGATNLWVKVEKDLTHYGDECTFGGGKSLREGMGQSSGKIAKECVDTVVTNALIIDWSGIYKADIGIKDGIIVGIGK 367
                   699********************************************************************************************** PP

  Urease_alpha  99 agnpdvmdgvdeelvigastevi 121
                   agnpdvmdgv+++lv+g+st+vi
    EEA21629.1 368 AGNPDVMDGVHPDLVVGSSTDVI 390
                   *********************98 PP

>> Urease_beta  Urease beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0      0.36   1.1e+03      50      67 ..      21      38 ..      12      43 .. 0.85
   2 !  137.5   0.0   3.8e-44   1.1e-40       1      97 [.     138     235 ..     138     236 .. 0.96

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.36
                 -HHHHTTEEE-SSTT-EE CS
  Urease_beta 50 dRekalGlrldipagtav 67
                 +R+ a+G+rl+ + +ta+
   EEA21629.1 21 QRRLARGVRLNHAEATAL 38
                 799********9988885 PP

  == domain 2  score: 137.5 bits;  conditional E-value: 3.8e-44
                  TT-EE-.SSSEEETTTT---EEEEEEE-SSS-EEEETTS-GGGS-TTEES-HHHHTTEEE-SSTT-EEEE-TT-EEEEEEEE-STT-EE-STTSS--E CS
  Urease_beta   1 pgeiit.eegeielnagretiklkvantgdrpiqvgshyhflevnkaLefdRekalGlrldipagtavrfepgeekevelvelaGerkvyGlnglvng 97 
                  pg++it ++++i+l++gr++iklkv+++gdrpiqvgshyhf+e+n++L+fdRe+a+G+rldi+agt++rfepg++k+v+lve++G++ + G n l++g
   EEA21629.1 138 PGAVITvKNSRITLSEGRKRIKLKVMSKGDRPIQVGSHYHFIETNPQLHFDRERAYGYRLDIAAGTSIRFEPGDTKTVTLVEIGGNKIISGGNFLASG 235
                  7888887999**********************************************************************************998887 PP

>> Urease_gamma  Urease, gamma subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  130.6   0.2     7e-42   2.1e-38       1      99 []       1     100 [.       1     100 [. 0.99
   2 ?    0.3   0.0       0.3   8.9e+02      48      82 ..     777     812 ..     762     817 .. 0.70

  Alignments for each domain:
  == domain 1  score: 130.6 bits;  conditional E-value: 7e-42
                   ----HHHHHHHHHHHHHHHHHHHHHTT--B-HHHHHHHHHHHHHHHHHCT.S-HHHHHHHHCCSS-CCCB-TTCHHH-SEEEEEEEETTEEEEEEEE CS
  Urease_gamma   1 mkLtpreldkLllfaaaelAqkrlarGlkLnhpEavaliasevlelardg.ksvaelmelgkklLtredvldgvaelleevqveatfpdgtkLvtvh 96 
                   m+L p+e+dkL++++++ lAq+rlarG++Lnh+Ea+ali+s+++el+rdg ++va+lm++gk++L+r++vl++v + l e+qve+tf+ gt Lvtvh
    EEA21629.1   1 MQLIPKEIDKLVISQLGLLAQRRLARGVRLNHAEATALISSNLQELIRDGnHTVADLMSIGKTMLGRRHVLPSVISSLVELQVEGTFRTGTYLVTVH 97 
                   9*************************************************999******************************************** PP

                   S-S CS
  Urease_gamma  97 dpi 99 
                   +pi
    EEA21629.1  98 HPI 100
                   **9 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.3
                   HCT.S-HHHHHHHHCCSS-CCCB-TTCHHH-SEEEE CS
  Urease_gamma  48 rdg.ksvaelmelgkklLtredvldgvaelleevqv 82 
                   r+  + v ++ ++gkk ++ +dv+++++   e+  v
    EEA21629.1 777 RKRiEPVRNCRNIGKKDMKFNDVMPKMKVDPERYTV 812
                   4444779999***************98765555555 PP

>> Amidohydro_3  Amidohydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   3.3e-06    0.0098       1      23 [.     388     410 ..     388     439 .. 0.77
   2 !   21.2   0.0   5.6e-08   0.00017     365     468 ..     621     722 ..     458     727 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 3.3e-06
  Amidohydro_3   1 eviDakGrlvlPGFvDsHtHlag 23 
                   +vi a+G++v++G+ D H+H + 
    EEA21629.1 388 DVIAAEGKIVTAGGFDTHIHFIC 410
                   69******************654 PP

  == domain 2  score: 21.2 bits;  conditional E-value: 5.6e-08
  Amidohydro_3 365 nagvkvalgsDapvgpfdpwprigaavmrktrrgg......evlrpdeelsleealalyTrgpAkalgledrkGtLevGadADlvvldadpldvdpp 455
                   + g   +++sD+     +    ++++++  + +++      +  +    + +   +  yT +pA a g+ +  G++evG+ ADlv++  d +  +p+
    EEA21629.1 621 DLGAISMMSSDSQAMGRCGEVILRTWNTAHKNKEQrgvlpeDEGTGADNFRVKRYISKYTINPAIAQGMVHLIGSVEVGKLADLVLWTPDNFGTKPK 717
                   55666666677666666666666777776666666766666444444478899999*******************************9888877764 PP

  Amidohydro_3 456 elaearvrltvvd 468
                           l+v++
    EEA21629.1 718 --------LVVKG 722
                   ........55555 PP

>> Amidohydro_2  Amidohydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00012      0.36      90     153 ..     464     527 ..     446     582 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00012
                   ECTSSHCHHHHHHHHHHHHTTECEEEEESSTTTCCTTTCGGHHHHHHHHHHHT-EEEEE.........C CS
  Amidohydro_2  90 vvpldpedaaaeleraveelgfkGvrlnphvggddllgdrldrpifealeelglpvdihtGps.....p 153
                   ++    ++ ++ l++++  +g+ G++l+ ++g    ++++ d  ++e++ e ++ ++iht +       
    EEA21629.1 464 ITGKGNDSGVESLREQA-IAGAAGMKLHEDWG---STPAAID-TCLEVCDEFDIQCMIHTDTLnesgfV 527
                   55555677889999999.99999999999999...5555666.9***************8765554441 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (836 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       449  (0.0250432); expected 358.6 (0.02)
Passed bias filter:                      413  (0.0230353); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.70u 0.30s 00:00:01.00 Elapsed: 00:00:00.48
# Mc/sec: 5196.67
//
Query:       EEA21630.1  [L=585]
Description: RING finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.1e-11   42.5   6.0    1.1e-10   41.7   6.0    1.5  1  zf-RING_2     Ring finger domain
    4.4e-09   35.9   3.7    4.4e-09   35.9   3.7    1.8  2  zf-RING_11    RING-like zinc finger
    1.6e-06   27.9   5.4    3.2e-06   26.9   5.4    1.6  1  zf-C3HC4_2    Zinc finger, C3HC4 type (RING finger)
      2e-06   27.6   3.5    4.1e-06   26.6   3.5    1.6  1  zf-C3HC4      Zinc finger, C3HC4 type (RING finger)
    6.5e-06   26.1   2.5    7.1e-06   26.0   1.2    1.8  1  zf-RING_UBOX  RING-type zinc-finger
    2.2e-05   24.3   2.7    4.1e-05   23.5   2.7    1.5  1  zf-RING_5     zinc-RING finger domain
    0.00027   20.7   3.5     0.0005   19.9   3.5    1.4  1  zf-C3HC4_3    Zinc finger, C3HC4 type (RING finger)
    0.00031   21.0   6.1     0.0017   18.6   6.1    2.2  1  zf-rbx1       RING-H2 zinc finger domain
     0.0015   18.3   4.6     0.0033   17.3   4.6    1.5  1  Prok-RING_4   Prokaryotic RING finger family 4
     0.0038   17.3   1.2     0.0091   16.0   0.9    1.8  2  zf-ANAPC11    Anaphase-promoting complex subunit 11 RING-H2 f
  ------ inclusion threshold ------
      0.045   14.0   0.1       0.11   12.7   0.1    1.6  1  DUF4381       Domain of unknown function (DUF4381)
      0.068   12.8   3.0       0.13   11.9   3.0    1.4  1  Zn_ribbon_17  Zinc-ribbon, C4HC2 type
       0.17   12.2   2.1       0.45   10.9   2.1    1.8  1  zf-RING-like  RING-like domain
       0.37   10.6   4.1       0.79    9.6   4.1    1.5  1  zf-Nse        Zinc-finger of the MIZ type in Nse subunit


Domain annotation for each model (and alignments):
>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.7   6.0   8.6e-14   1.1e-10       2      44 .]     390     434 ..     389     434 .. 0.89

  Alignments for each domain:
  == domain 1  score: 41.7 bits;  conditional E-value: 8.6e-14
   zf-RING_2   2 eCpICleelssadsvlll.pCgHvfhreClerwlrssst.CPlCr 44 
                 +C+ICl+++ +a+s++++ pC H+fh eC++++l++  + CP+C+
  EEA21630.1 390 TCAICLDDFVPAESLVRElPCMHIFHPECIDTFLARDAStCPVCK 434
                 7*************88666*************97777777****7 PP

>> zf-RING_11  RING-like zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.9   3.7   3.4e-12   4.4e-09       2      29 .]     391     419 ..     390     419 .. 0.95
   2 ?   -3.6   0.1       7.8     1e+04       2       9 ..     430     437 ..     430     440 .. 0.77

  Alignments for each domain:
  == domain 1  score: 35.9 bits;  conditional E-value: 3.4e-12
  zf-RING_11   2 CsICLeefkpgqal.filpCsHtFHfkCI 29 
                 C+ICL++f p ++l + lpC+H+FH +CI
  EEA21630.1 391 CAICLDDFVPAESLvRELPCMHIFHPECI 419
                 **********998868************9 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 7.8
  zf-RING_11   2 CsICLeef 9  
                 C +C +++
  EEA21630.1 430 CPVCKQNV 437
                 99998876 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.9   5.4   2.5e-09   3.2e-06       2      40 .]     391     433 ..     390     433 .. 0.88

  Alignments for each domain:
  == domain 1  score: 26.9 bits;  conditional E-value: 2.5e-09
  zf-C3HC4_2   2 CpiCldmlkdpsvvt...pCgHvfCqkCilrsLeekn.eCPlC 40 
                 C+iCld +  +  +    pC H f+ +Ci++ L +    CP+C
  EEA21630.1 391 CAICLDDFVPAESLVrelPCMHIFHPECIDTFLARDAsTCPVC 433
                 *******99775555688*************9999888***** PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.6   3.5   3.2e-09   4.1e-06       1      41 []     391     433 ..     391     433 .. 0.98

  Alignments for each domain:
  == domain 1  score: 26.6 bits;  conditional E-value: 3.2e-09
                 -TTT-S--SS-E....E-TTS--B-CHHHHHHHHCTSSB--TTT CS
    zf-C3HC4   1 CpiCleeakepn...elleCkHsfCskCirkilksrkkvkCPlC 41 
                 C+iCl+ ++ +    + l+C+H f+ +Ci++ l  r + +CP+C
  EEA21630.1 391 CAICLDDFVPAEslvRELPCMHIFHPECIDTFLA-RDASTCPVC 433
                 *********999999*******************.********* PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0   1.2   5.5e-09   7.1e-06       1      39 []     391     431 ..     391     431 .. 0.89

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 5.5e-09
  zf-RING_UBOX   1 CpIClelftdP...lv..lpCGHtFCreClwelskslegafkCP 39 
                   C ICl++f  P   lv  lpC H+F+ eC+   ++  ++a +CP
    EEA21630.1 391 CAICLDDF-VPaesLVreLPCMHIFHPECI--DTFLARDASTCP 431
                   ********.6668855677***********..8999*******9 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   2.7   3.2e-08   4.1e-05       2      44 .]     391     435 ..     390     435 .. 0.92

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 3.2e-08
   zf-RING_5   2 CnkCfekl.skeekfyltsCgHifCekClkkll.ekeavCpiCrk 44 
                 C +C + +   e+ +  ++C Hif+ +C+++ l     +Cp+C++
  EEA21630.1 391 CAICLDDFvPAESLVRELPCMHIFHPECIDTFLaRDASTCPVCKQ 435
                 9*******777777999****************9999******97 PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   3.5   3.9e-07    0.0005       2      47 ..     388     437 ..     387     438 .. 0.84

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 3.9e-07
                 GSB-TTTSSS....BS-EEETTEEEEEE-HHHHHHHHH.TT-B-TTT--B- CS
  zf-C3HC4_3   2 deeCviCler....prnvvllpCgHlvlCeeCaekllk.rkkkCpiCrrpi 47 
                 +++C iCl+     ++ v  lpC+H+ +  eC +++l+    +Cp+C++++
  EEA21630.1 388 QHTCAICLDDfvpaESLVRELPCMHI-FHPECIDTFLArDASTCPVCKQNV 437
                 679******6553255566789****.*********9989********986 PP

>> zf-rbx1  RING-H2 zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   6.1   1.3e-06    0.0017      31      55 .]     409     434 ..     388     434 .. 0.80

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 1.3e-06
     zf-rbx1  31 eCgHaFHlhCiskWlkt.rkvCPlcr 55 
                  C H FH +Ci++ l +  ++CP+c+
  EEA21630.1 409 PCMHIFHPECIDTFLARdASTCPVCK 434
                 7***************97889****6 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   4.6   2.6e-06    0.0033       1      41 [.     391     438 ..     389     442 .. 0.74

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 2.6e-06
  Prok-RING_4   1 CvlCgeq....ekkailepCgHlvCkeCfdsk...dlssCPlCqrris 41 
                  C +C       e+ ++  pC H++  eC d     d s+CP+C++++ 
   EEA21630.1 391 CAICLDDfvpaESLVRELPCMHIFHPECIDTFlarDASTCPVCKQNVL 438
                  555555555445555567******99998876666999******9985 PP

>> zf-ANAPC11  Anaphase-promoting complex subunit 11 RING-H2 finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.9   7.1e-06    0.0091      47      81 ..     404     437 ..     383     440 .. 0.80
   2 ?   -3.5   0.0       8.5   1.1e+04      63      79 ..     499     515 ..     497     516 .. 0.87

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 7.1e-06
                 EEEBT.TS-EEEHHHHHHHHHHHSTSSB-TTTSSB- CS
  zf-ANAPC11  47 lvlGk.ckhnfhlhcilkwletetskglcpmcrqtf 81 
                 lv    c h+fh  ci ++l++++s   cp+c+q++
  EEA21630.1 404 LVRELpCMHIFHPECIDTFLARDAS--TCPVCKQNV 437
                 455445***************9987..7*****975 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 8.5
                 HHHHHHSTSSB-TTTSS CS
  zf-ANAPC11  63 kwletetskglcpmcrq 79 
                  wl+++   ++ p+ rq
  EEA21630.1 499 AWLARDYDDDQSPVHRQ 515
                 69999999999999999 PP

>> DUF4381  Domain of unknown function (DUF4381)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.1   8.9e-05      0.11      18      53 ..     211     248 ..     201     253 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 8.9e-05
     DUF4381  18 apGwwlllaalll..llllvlalwllrrrkrnrreAlr 53 
                  pG+w+ ++a+l   +l++++a++ +r+ +++rre l+
  EEA21630.1 211 MPGMWVFILAVLGaiVLMVIFAFLTMRHVQKKRRESLQ 248
                 58888888777777777788888888888888888775 PP

>> Zn_ribbon_17  Zinc-ribbon, C4HC2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   3.0    0.0001      0.13       3      47 ..     387     432 ..     385     437 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.0001
  Zn_ribbon_17   3 llksCayC..elavkgrvvlcgvCeHvlHasCarewfenddlaeCps 47 
                   ++++Ca+C  +     ++v    C H+ H +C++  +  d  + Cp+
    EEA21630.1 387 SQHTCAICldDFVPAESLVRELPCMHIFHPECIDTFLARDA-STCPV 432
                   57888888433344566677788**************9999.99*97 PP

>> zf-RING-like  RING-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   2.1   0.00035      0.45      18      43 .]     409     433 ..     390     433 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00035
  zf-RING-like  18 sCnvrlHvdCfqhyirthsskkCpkC 43 
                    C  ++H +C+++++ ++   +Cp C
    EEA21630.1 409 PCMHIFHPECIDTFL-ARDASTCPVC 433
                   5999***********.88888***** PP

>> zf-Nse  Zinc-finger of the MIZ type in Nse subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   4.1   0.00061      0.79      25      56 ..     405     433 ..     385     434 .. 0.75

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00061
                 EEESSS--EEEHHHHHHHCTTTS-EE-SCCC- CS
      zf-Nse  25 vtskkCpHvFEreaIlelikrkktvkCPvagC 56 
                 v++  C H+F  e I +++  +++  CPv  C
  EEA21630.1 405 VRELPCMHIFHPECIDTFL-ARDASTCPV--C 433
                 55558**************.99999****..8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (585 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1165  (0.0649785); expected 358.6 (0.02)
Passed bias filter:                      928  (0.0517597); expected 358.6 (0.02)
Passed Vit filter:                       131  (0.0073066); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.72u 0.31s 00:00:01.03 Elapsed: 00:00:00.47
# Mc/sec: 3754.34
//
Query:       EEA21631.1  [L=665]
Description: transcriptional regulator Ngg1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-51  173.4   0.1    2.2e-51  173.4   0.1    2.0  2  Ada3      Histone acetyltransferases subunit 3


Domain annotation for each model (and alignments):
>> Ada3  Histone acetyltransferases subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.3      0.38   6.7e+03      28      28 ..     128     128 ..      96     173 .. 0.60
   2 !  173.4   0.1   1.2e-55   2.2e-51       2     132 .]     480     617 ..     479     617 .. 0.97

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 0.38
        Ada3  28 k 28 
                 k
  EEA21631.1 128 K 128
                 1 PP

  == domain 2  score: 173.4 bits;  conditional E-value: 1.2e-55
        Ada3   2 dyaqleeRlkqELreiGilepeedadkydgredDevaaeLrrlqaeLrevsliNgarkarLlelvkermayqeyqtiledlDkqvqqaYlKrtrtlkkk 100
                 ++aql+eRlk ELr++G+l +e+++d +d+++dD++a++Lr+lq eL++++l+Ngark+rLle++kermayqey+ti++dlD+qvqqaYlKrtrtl+k+
  EEA21631.1 480 EHAQLDERLKAELRYVGFLGAEDNPD-FDAHYDDDIAQRLRLLQGELKKQMLTNGARKTRLLEIAKERMAYQEYSTIHDDLDSQVQQAYLKRTRTLGKS 577
                 689**********************8.************************************************************************ PP

        Ada3 101 kkkkrsga........aaaaaaagaarpgigdalralmer 132
                 kk++++++        ++  +aag+ rpgigd++r+lm+r
  EEA21631.1 578 KKGSQAKHrpggagggSHIVSAAGVGRPGIGDMARTLMDR 617
                 ***99999*****999899999****************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (665 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1273  (0.0710023); expected 358.6 (0.02)
Passed bias filter:                      603  (0.0336327); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.71u 0.26s 00:00:00.97 Elapsed: 00:00:00.44
# Mc/sec: 4571.26
//
Query:       EEA21632.1  [L=639]
Description: nitrogen permease regulator Npr2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.4e-131  438.5   5.7   1.2e-127  426.3   0.0    3.0  2  NPR2      Nitrogen permease regulator 2
  ------ inclusion threshold ------
      0.095   13.1   0.2       0.25   11.8   0.0    1.8  2  MULE      MULE transposase domain
        2.2    8.1  13.5        1.7    8.5   7.7    2.1  2  SPX       SPX domain


Domain annotation for each model (and alignments):
>> NPR2  Nitrogen permease regulator 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  426.3   0.0  2.1e-131  1.2e-127       3     401 ..       2     420 ..       1     448 [. 0.90
   2 !    8.6   4.8   0.00011      0.68     331     439 ..     483     630 ..     455     631 .. 0.64

  Alignments for each domain:
  == domain 1  score: 426.3 bits;  conditional E-value: 2.1e-131
        NPR2   3 ikaifyavFhpteGtkivhqvPegsivtss.esdekealFeFdtvknyviPkpqlcnrllslkinkykvlgyPvnienekYsRneFtFnfafvidydes 100
                 ikaify++F  +eG k+vhqvP+g+iv+s+  s +++  F F+ +  +viP+++lc +ll ++ n y++lgyP++i+  +Y+RneF+Fnf+fv+ ++  
  EEA21632.1   2 IKAIFYSKFDTQEGPKVVHQVPDGAIVPSPtASPQQAPFFTFSDISFFVIPRQELCGNLLQVCTNGYRILGYPICIKSVQYDRNEFMFNFCFVLAEE-E 99 
                 89**************************9856788999********************************************************999.9 PP

        NPR2 101 dttpYesvvkrlgrllrvlEeqnkfLskedkdvvffksaklaeadatvnvpgasklssieslieqileDLnnysEcviplddsnsvdlKLfPilpePvn 199
                 d + Y s+v++l+ l+++lEeq+ fLs++                     +g+ k   ++sl+e+++eDLn ysEc+ip+d+ n++++KLfP++p+P+ 
  EEA21632.1 100 DFSKYKSIVQKLADLMHGLEEQSGFLSRDFS------------------KSGEGK---VYSLCETLMEDLNSYSECMIPIDKLNTLNFKLFPVYPAPPY 177
                 ***************************8655..................357778...***************************************** PP

        NPR2 200 ikayqvPiatvklsslvdvnwDltlkkilpyinGinsvkriaeladadlsLtkqciqhLlyYkcielldiFqfsniYaptneigdFlkdegeiadeCqa 298
                 +k++ vP+ tv++  ++d+nwDltl+ki+py+nG+nsv+ i+ lad++lsL  ++i+hLlyY+c+ lldiF+fs+iYapt++ +  ++ ++ +++eC++
  EEA21632.1 178 VKSWDVPLFTVRFDAFLDENWDLTLQKIVPYVNGVNSVRIISILADVELSLAYRAIRHLLYYGCVFLLDIFSFSAIYAPTASFNSSIASDEAMQQECAR 276
                 *************************************************************************************************** PP

        NPR2 299 yvvveeskl........................................gsnsvsplsktsllsksskkvteaka.deeevevkvpskttlfrLyrslk 356
                 yv ++ + +                                         sn  s + + +  +k ++     k+    +++ k  +   +++Ly sl+
  EEA21632.1 277 YVNTRFAPTsslrmatgsppsseyrgdlsgsashhriddteediwpmigDSNDDSDTDHDHDSHKNNAGSYLSKTrRRPRKKRKYLDGVGIVELYASLR 375
                 ***997666788999999999999999998888888888888888888766666666666666666555544444034566777888999********* PP

        NPR2 357 qgqtvkeWvlqekkllagiDvrRliqFGvlkgliyrvhkypilns 401
                 qgq+vk+W++++  +la++D+rR+i+FG++kg++yrvhky+    
  EEA21632.1 376 QGQSVKQWYTLNARQLANVDIRRFITFGIIKGFLYRVHKYAYGPR 420
                 ****************************************97655 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.00011
        NPR2 331 akadeeevevkvpskttlfrLyrslkqgqtvkeWvlqekkl..lagiDvrRliqFGvlkgliyrvhkypilnssak....................... 404
                 ++  +e++++++ +++++  +  s + +++ +    q+++l  +++i++ Rl   G   +   r+ + p ++ +++                       
  EEA21632.1 483 GRMGNEQQQQQQQQQQQVSVMSSSYQSTNNTHTNHSQNHSLtnSNNINI-RLGSAGTSFDTDPRHNQNPHQDENEHtninseihstesildddladees 580
                 4444444444444444444444444444444333333333312555655.5667777777777777777777766677777777777777777777777 PP

        NPR2 405 ...............antllksldglkslDellkelkvkeekleeklkkt 439
                                 ++l k+ldg++++De+++el+++e++l+ +l+++
  EEA21632.1 581 reggtaqeairfhqnHKALEKYLDGQHCFDEICTELEISERELTARLRQI 630
                 7777777778887768899************************9999875 PP

>> MULE  MULE transposase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   4.2e-05      0.25      21      66 ..      80     125 ..      65     132 .. 0.85
   2 ?   -3.4   0.1       2.3   1.4e+04      36      75 ..     473     512 ..     472     519 .. 0.63

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 4.2e-05
        MULE  21 vgvddngqlvplafalveseneesyewllqelleevsgqrspkvii 66 
                 v  d+n+ +++++f+l e+e+ + y+ ++q+l++ ++g ++++ ++
  EEA21632.1  80 VQYDRNEFMFNFCFVLAEEEDFSKYKSIVQKLADLMHGLEEQSGFL 125
                 56789999**************************999977776665 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 2.3
        MULE  36 lveseneesyewllqelleevsgqrspkviitDkekalln 75 
                 lv++e++    ++ +e +++  +q++++++++   ++  n
  EEA21632.1 473 LVSRESSIRHGRMGNEQQQQQQQQQQQVSVMSSSYQSTNN 512
                 5666666666666666666667767777777766666555 PP

>> SPX  SPX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.3     0.012        74      67     328 ..     260     354 ..     244     396 .. 0.55
   2 ?    8.5   7.7   0.00028       1.7      92     185 ..     480     598 ..     409     628 .. 0.55

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.012
         SPX  67 stsaaadesgnsaadasssepkdeae...........slprrsplsrssrssssygglvssppsansssssddssesnpadssssssssesessssssp 154
                  +s+ a++++++++ a   +++  ++           s++ r  ls+s ++++  +  +  +p   +s++++d +++                      
  EEA21632.1 260 FNSSIASDEAMQQECARYVNTRFAPTsslrmatgsppSSEYRGDLSGSASHHRIDDTEEDIWPMIGDSNDDSDTDHDH--------------------- 337
                 445555555555555544444444445555555555555555666666666666666666666666666666555555..................... PP

         SPX 155 sllrrlfsesesreeksersyetrplraekeFferLdseLnkvetFykakeeefterlesLrkqlealrprrikeaeerksdlyrwreifglksveaqv 253
                                                                                                                    
  EEA21632.1   - ---------------------------------------------------------------------------------------------------   -
                 ................................................................................................... PP

         SPX 254 fessreldrgelseeardkevseelekngwikptksklekkrneralekvkpektlkafldsvrrdylrkenrvk 328
                                                                          + ++++  +yl+k +r +
  EEA21632.1 338 ---------------------------------------------------------DSHKNNAGSYLSK-TRRR 354
                 .........................................................1111122222222.2222 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00028
         SPX  92 e.........slprrsplsrssrssssygglvssppsansssssddssesnpa.............dssssssssesesssssspsllrrlfs...ese 165
                           +++++++ ++ s  sssy++ +++++++++++s  +s++ n +              ++++++++++ ++ +s+ ++++++++   + e
  EEA21632.1 480 IrhgrmgneqQQQQQQQQQQVSVMSSSYQSTNNTHTNHSQNHSLTNSNNINIRlgsagtsfdtdprHNQNPHQDENEHTNINSEIHSTESILDddlADE 578
                 022223222233333334444444444444444444444444444444444445555555444333222233333333333333333333333555667 PP

         SPX 166 sreeksersyetrplraeke 185
                 +++e ++ +  +r+ ++ k+
  EEA21632.1 579 ESREGGTAQEAIRFHQNHKA 598
                 77777777766666664444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (639 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2090  (0.116571); expected 358.6 (0.02)
Passed bias filter:                      789  (0.0440069); expected 358.6 (0.02)
Passed Vit filter:                        75  (0.00418317); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.76u 0.29s 00:00:01.05 Elapsed: 00:00:00.43
# Mc/sec: 4493.86
//
Query:       EEA21633.1  [L=293]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.028   14.2   3.6       0.47   10.3   2.5    2.6  2  SinI      Anti-repressor SinI
       0.23   11.5   0.6       0.45   10.5   0.6    1.4  1  DUF1656   Protein of unknown function (DUF1656)


Domain annotation for each model (and alignments):
>> SinI  Anti-repressor SinI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0     0.019   1.7e+02      14      22 ..      85      93 ..      85      95 .. 0.88
   2 ?   10.3   2.5   5.2e-05      0.47       1      16 [.     209     224 ..     209     224 .. 0.93

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.019
                HHT--SHHH CS
        SinI 14 esGlskeEf 22
                e Gl+k+E+
  EEA21633.1 85 ELGLTKQEI 93
                68******9 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 5.2e-05
                 THHHHHHHHHHHHHHT CS
        SinI   1 LDeEWveLikEAkesG 16 
                 LDeEW++ +kEA+e G
  EEA21633.1 209 LDEEWEQWLKEARERG 224
                 9************965 PP

>> DUF1656  Protein of unknown function (DUF1656)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.6   5.1e-05      0.45      31      47 ..      66      82 ..      65      83 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 5.1e-05
     DUF1656 31 arlglyrlvWhpaLfdl 47
                +r +l+r+ Wh+ Lf +
  EEA21633.1 66 HRMRLSRFPWHRKLFKV 82
                699************75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (293 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       428  (0.0238719); expected 358.6 (0.02)
Passed bias filter:                      357  (0.0199119); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.40
# Mc/sec: 2187.65
//
Query:       EEA21634.1  [L=293]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.028   14.2   3.6       0.47   10.3   2.5    2.6  2  SinI      Anti-repressor SinI
       0.23   11.5   0.6       0.45   10.5   0.6    1.4  1  DUF1656   Protein of unknown function (DUF1656)


Domain annotation for each model (and alignments):
>> SinI  Anti-repressor SinI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0     0.019   1.7e+02      14      22 ..      85      93 ..      85      95 .. 0.88
   2 ?   10.3   2.5   5.2e-05      0.47       1      16 [.     209     224 ..     209     224 .. 0.93

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.019
                HHT--SHHH CS
        SinI 14 esGlskeEf 22
                e Gl+k+E+
  EEA21634.1 85 ELGLTKQEI 93
                68******9 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 5.2e-05
                 THHHHHHHHHHHHHHT CS
        SinI   1 LDeEWveLikEAkesG 16 
                 LDeEW++ +kEA+e G
  EEA21634.1 209 LDEEWEQWLKEARERG 224
                 9************965 PP

>> DUF1656  Protein of unknown function (DUF1656)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.6   5.1e-05      0.45      31      47 ..      66      82 ..      65      83 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 5.1e-05
     DUF1656 31 arlglyrlvWhpaLfdl 47
                +r +l+r+ Wh+ Lf +
  EEA21634.1 66 HRMRLSRFPWHRKLFKV 82
                699************75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (293 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       428  (0.0238719); expected 358.6 (0.02)
Passed bias filter:                      357  (0.0199119); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.24s 00:00:00.70 Elapsed: 00:00:00.41
# Mc/sec: 2135.35
//
Query:       EEA21635.1  [L=641]
Description: DNA repair protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.5e-07   30.4   0.0    5.4e-07   29.3   0.0    1.5  1  Lactamase_B_2  Beta-lactamase superfamily domain
    2.2e-06   27.8   0.1    8.4e-06   25.9   0.1    2.0  1  DRMBL          DNA repair metallo-beta-lactamase
    0.00011   22.3   0.0    0.00022   21.3   0.0    1.4  1  Lactamase_B    Metallo-beta-lactamase superfamily
  ------ inclusion threshold ------
      0.027   14.4   0.0      0.066   13.2   0.0    1.6  1  RMMBL          Zn-dependent metallo-hydrolase RNA specificity


Domain annotation for each model (and alignments):
>> Lactamase_B_2  Beta-lactamase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.3   0.0   1.2e-10   5.4e-07      28     167 ..      20     161 ..      11     198 .. 0.66

  Alignments for each domain:
  == domain 1  score: 29.3 bits;  conditional E-value: 1.2e-10
                    ..SEEEEE-SS--HHHHGGGGCCCC.C--EEEEEEEEHHHHH...HCCTTCGHHHCHTT..TTEEEEEE-TTSEEEE...............CSTT CS
  Lactamase_B_2  28 lppidaVllthaHyDHlaglltlre.lrpkklplyapkgvla...vleanfvylaleee..pavnvheldwgesfel...............gdgg 102
                    +pp+ + +l+h H DHl+gl ++r  +      +y+++ +++    le+  ++ +      +++++++ + g+  ++                   
     EEA21635.1  20 PPPL-VCFLSHVHSDHLQGLESFRSpF------IYCSAVTRElllRLEKFPHRMN---FskGILEARKQHYGHLAKIlrpiplntpteieltPLQR 105
                    3444.489*****************32......7788888873333333333222...23434444444444444444444432111113342224 PP

                    EEEEEEEE-EE--CTCCE-TTTSEEEEEECTTEEEEEESS-S---HHHHHHHCT-SEEEEE-S-S CS
  Lactamase_B_2 103 leitatparhksgrrldrnagdtlGlriegggkrvyyigDtgyipeeigerlggadllllditay 167
                    +++t+  a+h +g         ++ l+ieg+gk+++y+gD    ++++  +++ + l+ + +++ 
     EEA21635.1 106 VRVTLLDANHCAG---------AVMLLIEGQGKAILYTGDIRAESWWVNSLIRHPALVPYACGLK 161
                    5555555555555.........59*****************998888888888777776666655 PP

>> DRMBL  DNA repair metallo-beta-lactamase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.9   0.1   1.9e-09   8.4e-06      71     106 ..     412     447 ..     391     452 .. 0.80

  Alignments for each domain:
  == domain 1  score: 25.9 bits;  conditional E-value: 1.9e-09
       DRMBL  71 rekisiyrvpYSeHSSfrELkefvkslkpkkiiptV 106
                   ++ +   pYS HSS+ EL+e v+++kpk ++p +
  EEA21635.1 412 YPDTATITFPYSRHSSYAELCELVQAFKPKDVFPCT 447
                 455677889************************943 PP

>> Lactamase_B  Metallo-beta-lactamase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.0     5e-08   0.00022      38     151 ..      14     137 ..      10     165 .. 0.92

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 5e-08
                  HTSGGGGEEEEE.-SBSSHHHHTTGGGCTTHHCCEETCCEHHHHCCHCHHHHHHHHHCCHH.........TTCHCGCCEEEEETTTEECCCTEEEEEH CS
  Lactamase_B  38 lglkpkdvdavi.lTHlHlDHiGglgglveatdvpvgavaeeapalfmeeaddaasrkgll.........lagvsadkpdvdeeeldgnaggrralyv 125
                  +++++k++  v+ l+H H+DH  gl+ +++ + +++++ +e +  l+++ +   +s++ l+         +++ ++++  +++e++ + +  +r +  
   EEA21635.1  14 RKVPDKPPPLVCfLSHVHSDHLQGLESFRSPFIYCSAVTRELLLRLEKFPHRMNFSKGILEarkqhyghlAKILRPIPLNTPTEIELTPLQRVRVTLL 111
                  5667777777766**************************************9999999888*********999************************* PP

                  ECTTSTSCCEEEEEETTCCEEEECTT CS
  Lactamase_B 126 tggpghghghgvveygggkvlftGDa 151
                     +  g++ + +e +g+ +l+tGD 
   EEA21635.1 112 DANHCAGAVMLLIEGQGKAILYTGDI 137
                  *************************7 PP

>> RMMBL  Zn-dependent metallo-hydrolase RNA specificity domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   1.5e-05     0.066      11      37 ..     420     446 ..     416     452 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.5e-05
       RMMBL  11 idfSgHadknellelirklkprnvilv 37 
                 + +S H+ ++el el++ +kp+ v++ 
  EEA21635.1 420 FPYSRHSSYAELCELVQAFKPKDVFPC 446
                 679**********************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (641 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       859  (0.0479112); expected 358.6 (0.02)
Passed bias filter:                      586  (0.0326845); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.66u 0.27s 00:00:00.93 Elapsed: 00:00:00.45
# Mc/sec: 4248.92
//
Query:       EEA21636.1  [L=304]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-53  179.9   3.4    4.3e-53  179.9   3.4    2.2  2  FRG1      FRG1-like domain
  ------ inclusion threshold ------
       0.07   13.4   0.0       0.22   11.8   0.0    1.9  2  Fascin    Fascin domain
       0.16   12.5   0.0       0.16   12.5   0.0    3.0  3  ABA_WDS   ABA/WDS induced protein


Domain annotation for each model (and alignments):
>> FRG1  FRG1-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.6       1.1   6.3e+03     127     165 ..      21      26 ..       6      50 .. 0.45
   2 !  179.9   3.4   7.2e-57   4.3e-53       1     191 []      89     302 ..      89     302 .. 0.93

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 1.1
        FRG1 127 drirvedreklrekeskyvkkfqkiqdkklrldkedvkr 165
                 d+ +                                 ++
  EEA21636.1  21 DDES---------------------------------NE 26 
                 1111.................................12 PP

  == domain 2  score: 179.9 bits;  conditional E-value: 7.2e-57
        FRG1   1 asylealdeGdftigePhdegegPdPeevftavkvasdekislKsgyGkYlgvdkegilsaraeAisseEqfevvfeegktallal............. 86 
                 as+le++++ d++++ePhd+      ++v++a++va++e++s+K+++G+Yl++dk+gilsa+a Ais+ E+f+ +   +++++lal             
  EEA21636.1  89 ASELENTIDNDPRTAEPHDV------RQVWVATRVAGTEGFSFKGHHGRYLSCDKYGILSATAAAISPFESFIAIQPPDTPGMLALqtrggesdtfiti 181
                 699*****************......************************************************9999999999999999999999999 PP

        FRG1  87 .........aketflsvdeekdivakskkaaeeevveiRsdaer.egktkdrirvedreklrekeskyvkkfqkiqdkkl......rldkedvkrlkka 169
                          ++   l  +e++d   k +k + ++++e+R+da++ +++++ rir+++r+k++ k+sk+ k+++ki++k+l      rl++ +vkrlk+a
  EEA21636.1 182 tekpsttsnNTTRRLINSEDGDEDDKDSKENGNKKIEVRGDANSiSFSSTLRIRMQARFKPKLKASKESKAREKISRKELeatvgrRLEDHEVKRLKRA 280
                 9888888754445566666677777888889999*********9999**************************************************** PP

        FRG1 170 rkeGnlhEvlLDrrvkmksDky 191
                 r+eGn++E++LD+rvk+k+Dk+
  EEA21636.1 281 RREGNYYEEVLDVRVKGKHDKF 302
                 *********************9 PP

>> Fascin  Fascin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   3.6e-05      0.22      25      61 ..     110     146 ..      80     156 .. 0.74
   2 ?   -2.6   0.0       1.1   6.3e+03       8      23 ..     238     253 ..     235     272 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3.6e-05
                 GEEEEEEETTSEEEEEEETTSEEEEE-TTSBEEEEES CS
      Fascin  25 qlftLefdeesyavaLrshngkYlsldkdGrvvaeae 61 
                 q++  +   ++    ++ h g+Yls+dk G + a+a 
  EEA21636.1 110 QVWVATRVAGTEGFSFKGHHGRYLSCDKYGILSATAA 146
                 6666666666777778888888888888888777765 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.1
                 TTSCCBEEEEESSSSG CS
      Fascin   8 ekrgaklsasaesekk 23 
                  +++ kl+as+es  +
  EEA21636.1 238 ARFKPKLKASKESKAR 253
                 5778888888766554 PP

>> ABA_WDS  ABA/WDS induced protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.5      0.29   1.7e+03      62      76 ..      35      49 ..      31      51 .. 0.76
   2 ?   12.5   0.0   2.6e-05      0.16      23      69 ..      84     131 ..      78     138 .. 0.86
   3 ?   -2.7   0.2       1.4   8.3e+03       8      16 ..     249     257 ..     245     282 .. 0.53

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.29
     ABA_WDS 62 afhEhhekkeakkea 76
                  hE+he++++ +e+
  EEA21636.1 35 IAHEQHEEQNTTTED 49
                579999998887765 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 2.6e-05
     ABA_WDS  23 aGA.falyEkheakkdpeharrHkieeeiaaavAvGsgGyafhEhhek 69 
                  GA fa   +     dp  a+ H +++   a+   G+ G+ f  hh +
  EEA21636.1  84 NGAvFASELENTIDNDPRTAEPHDVRQVWVATRVAGTEGFSFKGHHGR 131
                 56547777788899*************99999999***********76 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 1.4
     ABA_WDS   8 ehkhkerlg 16 
                 e k +e+++
  EEA21636.1 249 ESKAREKIS 257
                 555555543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (304 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1219  (0.0679904); expected 358.6 (0.02)
Passed bias filter:                      484  (0.0269954); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 2161.35
//
Query:       EEA21637.1  [L=347]
Description: alcohol dehydrogenase, zinc-containing, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-35  121.8   3.3    2.7e-35  120.5   1.9    2.1  2  ADH_N            Alcohol dehydrogenase GroES-like domain
    2.9e-15   56.4   0.0    4.7e-15   55.7   0.0    1.3  1  ADH_zinc_N       Zinc-binding dehydrogenase
    2.1e-12   47.0   0.0    3.3e-12   46.3   0.0    1.3  1  Glu_dehyd_C      Glucose dehydrogenase C-terminus
    2.3e-07   31.9   0.0    3.8e-07   31.2   0.0    1.4  1  ADH_zinc_N_2     Zinc-binding dehydrogenase
     0.0084   15.4   0.1      0.014   14.7   0.1    1.3  1  FAD_binding_3    FAD binding domain
  ------ inclusion threshold ------
        0.1   12.7   0.2       0.32   11.1   0.2    1.9  1  NADH_4Fe-4S      NADH-ubiquinone oxidoreductase-F iron-sulfur
       0.11   12.8   0.0       0.18   12.1   0.0    1.3  1  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma
       0.17   12.0   0.8         10    6.3   0.2    2.8  3  DUF2318          Predicted membrane protein (DUF2318)


Domain annotation for each model (and alignments):
>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  120.5   1.9   1.2e-38   2.7e-35       2     108 ..      32     136 ..      31     137 .. 0.97
   2 ?   -0.1   0.0      0.39   8.6e+02      30      64 ..     235     269 ..     224     275 .. 0.79

  Alignments for each domain:
  == domain 1  score: 120.5 bits;  conditional E-value: 1.2e-38
                 TEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS--TT-EEEE-SEEE-SSSHHHHTT-GGG-TTBEETTTSS-SSSBSEEE CS
       ADH_N   2 gevlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkklkvGdrVvvepliscgeCaaCkegeenlCeeakllgvsldGgfaeyvv 100
                 ++vlikvka+g+Cg+Dlhi +g  e+ +k+pl++GHE+vG+v++vgp+vk+++ GdrVv++    cgeC +C++gee lCe+ + +gv+++Ggfaey+ 
  EEA21637.1  32 NDVLIKVKACGVCGTDLHIHEG--EFLAKFPLVPGHETVGVVAAVGPKVKGFELGDRVVADNSELCGECFYCRRGEELLCEHFEAHGVTMNGGFAEYCA 128
                 79*******************9..7************************************************************************** PP

                 ECGGGEEE CS
       ADH_N 101 vpekklvk 108
                  p+  ++k
  EEA21637.1 129 YPAGRVFK 136
                 **998887 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.39
                 SSSEE---EEEEEEEEESTT-CS--TT-EEEE-SE CS
       ADH_N  30 klplilGHEivGeveevgpevkklkvGdrVvvepl 64 
                 ++++ +  E++G v+ ++++++ ++ G + vv+ +
  EEA21637.1 235 PYGFDIVVEATGSVKILEDSINYVRRGGKLVVYGV 269
                 5555666799***********99999999888765 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.7   0.0   2.1e-18   4.7e-15       2     127 ..     177     306 ..     176     309 .. 0.85

  Alignments for each domain:
  == domain 1  score: 55.7 bits;  conditional E-value: 2.1e-18
                 HHHHHHHHHH.HTT-EEEEEESSHHHHHHHHHTT.ESEEEETTTCHHHHHHHHHT..TTSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSC..TSSE CS
  ADH_zinc_N   2 vGlaavqlAk.alGaeviavdsseeklelakklG.adevinykeadlverikelt..ggegvdvvfecvGsgatleaalkllkpgGrlvvvGg..gkge 94 
                  Gl + q+++   G++v+++++   k elak+lG  de+i  ++ +++ + ++l   ++ g+d+v+e++Gs + le++++++++gG+lvv+G+  +k+ 
  EEA21637.1 177 TGLVLSQMLRqNGGCHVVVAAPEGLKMELAKQLGaGDEYISLSRSNPEVQFEKLKseNPYGFDIVVEATGSVKILEDSINYVRRGGKLVVYGVyaSKDR 275
                 699999999978888*******************66999999555666666666644699*********************************755555 PP

                 EEEEHHHHHHTT-EEEEE-SSCHHHHHHHHHHH CS
  ADH_zinc_N  95 eefdlrnlllkeksilGsllgslreefkealdl 127
                  + ++++++  e++ilGs+  +   +f++a+d 
  EEA21637.1 276 VSWPPSKIFGDEITILGSFSET--YKFPAAIDY 306
                 5588888************988..778777765 PP

>> Glu_dehyd_C  Glucose dehydrogenase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.3   0.0   1.5e-15   3.3e-12       5     212 .]     146     346 ..     143     346 .. 0.79

  Alignments for each domain:
  == domain 1  score: 46.3 bits;  conditional E-value: 1.5e-15
  Glu_dehyd_C   5 vLvEPisiveKaielaeasrsafewepesalvlGaGslGLLalalleaeerglervyvlgrrdrpdptidlveelGa..tYvd.sretp...vdeip. 95 
                   L+EP s ++ ++++++          +s+l+ GaG+ GL+   +l++ + g    +v+ +   ++++++l ++lGa   Y+  sr +p    +++  
   EEA21637.1 146 TLLEPASCAAHGLDKIAPK------MGSSVLMFGAGPTGLVLSQMLRQ-NGGC---HVVVA-APEGLKMELAKQLGAgdEYISlSRSNPevqFEKLKs 232
                  6889999999999987654......34699************999995.4444...45554.4679*********99556997344443211333321 PP

  Glu_dehyd_C  96 easeemdlvvEaTGsakhafeaiealapnGvaaLlGvpeds.evevdggelhrelvleNkalvGsvNanrrhfeaavdtLaalpeslldelvtkvvdl 192
                  e    +d+vvEaTGs k + ++i+ ++  G  +  Gv++++ +v+   +++  +       ++Gs  +++ +f aa+d L++ + + +  +v k  +l
   EEA21637.1 233 ENPYGFDIVVEATGSVKILEDSINYVRRGGKLVVYGVYASKdRVSWPPSKIFGD----EITILGSF-SETYKFPAAIDYLDRGKVK-VGGIVNKTFKL 324
                  233469********************************9986788888877766....67899*97.88999*********99877.579******** PP

  Glu_dehyd_C 193 deleeAfe..dddetiKtvvel 212
                  ++++e  e  +++  iK+++ +
   EEA21637.1 325 EQWAECLEamRNKSAIKAAITF 346
                  *****99855678899999976 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.2   0.0   1.7e-10   3.8e-07      11     127 ..     224     339 ..     179     340 .. 0.87

  Alignments for each domain:
  == domain 1  score: 31.2 bits;  conditional E-value: 1.7e-10
                   STTHH..HHH-TT-EEEEEES-HHHHH.HHHHHHEEEEEEEEE----.S-EEE-CHHHCTTT-EEEE--GGG...-.-HHHHHHHHHHHHHHH---. CS
  ADH_zinc_N_2  11 tedfe..aatggegvDvvldtvggealleaslkvlpggGrlvsiggpplsaallkpakkrkgrsvkyeflfsmkasaqadileelaalieeGklrp. 104
                   + +fe  ++ ++ g+D+v++++g+ ++le+s+++++ gG+lv++g    ++++++p++k  g  +++   fs +++   + + +  ++++ Gk+++ 
    EEA21637.1 224 EVQFEklKSENPYGFDIVVEATGSVKILEDSINYVRRGGKLVVYGVYASKDRVSWPPSKIFGDEITILGSFS-ETY---K-FPAAIDYLDRGKVKVg 315
                   5667788788899**********************777****999656889999999999999999999995.444...5.999*********9964 PP

                   .-EEEEEEGGGHHHHHHHHHSS-- CS
  ADH_zinc_N_2 105 .vvdrvfpleeaaeAhrylesgra 127
                     v+++f+le+ ae ++++++++a
    EEA21637.1 316 gIVNKTFKLEQWAECLEAMRNKSA 339
                   48**************99998765 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.1   6.2e-06     0.014       3      30 ..     168     195 ..     167     223 .. 0.92

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 6.2e-06
                    EEEEE--SHHHHHHHHHHHHTTHHEEEE CS
  FAD_binding_3   3 dVlIVGaGpaGlmlallLseaGvrvvlv 30 
                    +Vl  GaGp+Gl+l+++L++ G  +v+v
     EEA21637.1 168 SVLMFGAGPTGLVLSQMLRQNGGCHVVV 195
                    69999*****************988888 PP

>> NADH_4Fe-4S  NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.2   0.00014      0.32      12      34 ..      92     114 ..      87     163 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00014
                  HH--S--HHHHIIIIHHHHHHHH CS
  NADH_4Fe-4S  12 aesCGkCtpCreGtkrlleller 34 
                  +e CG+C+ Cr G + l e +e 
   EEA21637.1  92 SELCGECFYCRRGEELLCEHFEA 114
                  578**********9999887765 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0     8e-05      0.18       1      97 [.     169     266 ..     169     279 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 8e-05
                      EEEE--SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHHHTTS....SEEEE-SSGG.GHHHHHHHH CS
  Sacchrp_dh_NADP   1 vliiGaGsvGqavaellarhfdvdaeitvadrskeklealaakalgvrfeaialdaenyeavLaallkeg....dlvvnlsppi.ssldvlkaC 89 
                      vl++GaG +G ++ ++l +++    +++va ++  k+e +  k+lg   e i+l ++n+e   ++l +e+    d+vv +++++   +d + + 
       EEA21637.1 169 VLMFGAGPTGLVLSQMLRQNGGC--HVVVAAPEGLKMELA--KQLGAGDEYISLSRSNPEVQFEKLKSENpygfDIVVEATGSVkILEDSINYV 258
                      89*******************99..9****9999995544..5589999999999999999899988877899999999999885455666666 PP

                      HHHT-EEE CS
  Sacchrp_dh_NADP  90 ietgvhyv 97 
                      ++ g ++v
       EEA21637.1 259 RRGGKLVV 266
                      66666665 PP

>> DUF2318  Predicted membrane protein (DUF2318)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.0     0.055   1.2e+02      18      51 ..      22      55 ..       6      57 .. 0.71
   2 ?    6.3   0.2    0.0045        10      31      56 ..      86     111 ..      77     125 .. 0.88
   3 ?   -1.8   0.0       1.5   3.4e+03      64      76 ..     182     194 ..     177     203 .. 0.75

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.055
     DUF2318 18 vrflvvkksdgklrvaldaCevCekkgYvqegee 51
                v++ v   +d+ + + + aC vC+ + +++ege 
  EEA21637.1 22 VEIPVPTLRDNDVLIKVKACGVCGTDLHIHEGEF 55
                555555667888889999*****99888887765 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0045
     DUF2318  31 rvaldaCevCekkgYvqegeelvCkn 56 
                 rv+ d  e+C++  Y  +geel C++
  EEA21637.1  86 RVVADNSELCGECFYCRRGEELLCEH 111
                 68999*******************86 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 1.5
     DUF2318  64 dsigekkGGCnpi 76 
                 +++ +++GGC+ +
  EEA21637.1 182 SQMLRQNGGCHVV 194
                 5566699***866 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (347 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       370  (0.020637); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.48
# Mc/sec: 2181.83
//
Query:       EEA21638.1  [L=426]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.055   13.1   0.1       0.19   11.4   0.0    1.9  2  SLT       Transglycosylase SLT domain


Domain annotation for each model (and alignments):
>> SLT  Transglycosylase SLT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   1.1e-05      0.19       5      42 ..     106     146 ..     102     156 .. 0.86
   2 ?   -2.1   0.1      0.16   2.9e+03      42      97 ..     187     214 ..     178     224 .. 0.56

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 1.1e-05
                 HHHHHHTS-HHHHHHHHHHHHTT-TT-B-...TTSEBTTTT CS
         SLT   5 kaekkygvepsllaaiaqvESgfnpkAvs...ksgavGLmQ 42 
                   +   gv+p++++ai ++ES++  ++     +++  GLmQ
  EEA21638.1 106 SVSASSGVDPRFILAILMQESNGCVRVHTtnyGVNNPGLMQ 146
                 5567889****************998877778999*****9 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.16
                 TBETTTHHHHHHHHT-SHHHHCSHHHHHHHHHHHHHHHHHTTTT....HHHHHHHHHHH- CS
         SLT  42 QimpstakrlglrvklsedelldPeknisagakyLkslykqyng....slllalaAYNaG 97 
                 Q+ ++ ++r+g                                     + + a+  YN+G
  EEA21638.1 187 QLLDQAVSRYG--------------------------------AngatEYYVAARMYNSG 214
                 44444444444................................33333444444445555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (426 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       519  (0.0289475); expected 358.6 (0.02)
Passed bias filter:                      382  (0.0213063); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 3049.88
//
Query:       EEA21639.1  [L=1244]
Description: ubiquitin-protein ligase (Hul4), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      1e-75  255.1   0.0    1.4e-75  254.7   0.0    1.2  1  HECT           HECT-domain (ubiquitin-transferase)
  ------ inclusion threshold ------
       0.11   12.3   0.3       0.28   11.0   0.3    1.7  1  ITAM_Cys-rich  Immunoreceptor tyrosine-based activation motif


Domain annotation for each model (and alignments):
>> HECT  HECT-domain (ubiquitin-transferase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  254.7   0.0   1.5e-79   1.4e-75       2     306 ..     913    1243 ..     912    1244 .] 0.95

  Alignments for each domain:
  == domain 1  score: 254.7 bits;  conditional E-value: 1.5e-79
                  HHHHHHT-GGGSSEEESSTTSSSEEE-TTHHHHS....HHHHHHHHHHHHHTT--BSS-B-HHHHHHHTT..............-.---TCHHHHH- CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..............xxxxxxxxxxxxx RF
        HECT    2 llskelldpklglfeeesedsgtlypkpssseeellklfeflGkvlGkaiyeeilldlpfsraflkfllg..............eekitledleeid 84  
                  ll++e++dp++glf++ ++ds+ +y++p+  e++  ++f ++G++lG+aiy++ +ld+ ++++ +k+ll                ++ +l+dl+e+ 
  EEA21639.1  913 LLVREVFDPNHGLFTY-DDDSQFCYFNPYCFESS--EQFFLVGVLLGLAIYNSTILDIALPPFAFKKLLAaapstsipaaaqrqPHTSSLDDLAEYR 1006
                  799***********75.99999*******86644..58*******************************************998447889******* PP

                  HHHHHHHHHHH..HS-GGG...GT-BSEEEEE.TTEEEEEESSTTGGGSB--TTTHHHHHHHHHHHHHTGGGHHHHHHHHHHHHTTS-HHHHTTS-H CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        HECT   85 pelakslkellslesnteevedlaLtFtipen.agasatieLipnGanipVtnenkkeYiklyvnyllkksvekqleaflkGfsevipskalklfda 180 
                  p+lak l+ ll+++ +    e+++ +F+ + + +g+  ++ L+pnG+n pVtn+n++e+++lyv+y l+ sv++q+e f++Gf++v+  +al+lf++
  EEA21639.1 1007 PALAKGLRALLEFDGDV--QETFCYDFVAQVDrYGQVVNVPLCPNGENKPVTNTNRHEFVSLYVQYILDISVQRQFEPFKRGFYTVCGGNALALFRP 1101
                  ***********997766..5889*****99999**************************************************************** PP

                  HHHHHHHBCSSS.--HHHHHHTEEEETT--TTS...................HHHHHHHHHHHHS-HHHHHHHHHHHHSSSS--TTCGGG-B--EEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        HECT  181 eelellisGedelidvedlrrnteykggynaes...................etiewlweilkefspeekrlfLqFvTgssrlPlgGfaelhpkfti 258 
                  ee+el++ G+de +dv +lr++++y++  +++                    +ti w+w+ l + +p ++r++L FvTgs+r+P++G a+l  ++ i
  EEA21639.1 1102 EEIELMVRGSDEPLDVPTLRAVATYENWPTSQPkpndknnkdanteaeptsePTICWFWDFLARSTPTNQRKLLSFVTGSDRIPATGAASL--SIRI 1196
                  *************************8854444478889999**************************************************..**** PP

                  EE-S..-TTS--EEEGGGTEEEE---SSHHHHHHHHHHHHHHHH--XX CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        HECT  259 erkskedetrLPtahTCfnlLklpdYsskeilkekLltAieetegFel 306 
                  ++ + ed++r+P ahTCfn L l +Y+s+++l++ L  Ai ++egF+l
  EEA21639.1 1197 SCLG-EDSSRYPIAHTCFNKLGLFRYASRQKLERMLWDAICNSEGFGL 1243
                  **98.*****************************************98 PP

>> ITAM_Cys-rich  Immunoreceptor tyrosine-based activation motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.3   3.1e-05      0.28       4      16 ..    1212    1224 ..    1210    1225 .. 0.93

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 3.1e-05
  ITAM_Cys-rich    4 cYRtLsvFRYkSR 16  
                     c+ +L++FRY SR
     EEA21639.1 1212 CFNKLGLFRYASR 1224
                     99**********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1244 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       490  (0.02733); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.81u 0.26s 00:00:01.07 Elapsed: 00:00:00.46
# Mc/sec: 8194.87
//
Query:       EEA21640.1  [L=203]
Description: 60S ribosomal protein L15 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.9e-88  293.9  10.6      6e-88  293.6  10.6    1.0  1  Ribosomal_L15e  Ribosomal L15


Domain annotation for each model (and alignments):
>> Ribosomal_L15e  Ribosomal L15
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  293.6  10.6   3.4e-92     6e-88       1     187 [.       2     187 ..       2     190 .. 0.98

  Alignments for each domain:
  == domain 1  score: 293.6 bits;  conditional E-value: 3.4e-92
                     -SHHHHHHHTTSTTSHHHHHHHHHHHHHHTTS-SEEEESS-SSHHHHHHHT--SSTTEEEEEEEEE-SS---..---SS---GGGG-SSS---SS CS
  Ribosomal_L15e   1 gaykylrelwkkkqsdvlrellrerlweyrqepavvrverptrldrArrLGYkakqGivvvrvrvrrGgrkkkvskgktgrkpkrqgvnklkpak 95 
                     ga ky++el+kkkqsdvlr+llr+r+we rq+++++r++rp+r+d+ArrLGYkakqG+v++rvrvrrGgrk++++kg+t++kp++qg+n+lk ++
      EEA21640.1   2 GALKYVEELQKKKQSDVLRFLLRVRCWELRQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGGRKRPAPKGATYGKPTNQGINQLKYQR 96 
                     689******************************************************************************************** PP

                     -HHHHHHHHHHHHSTTSEEEEEEEEEEESSEEEEEEEEE-TTSHHHHT-TTTGGGGSGGGTTGGGGT-SHHHHHHTT-S-SS.TT-TTTSS- CS
  Ribosomal_L15e  96 slqaiaeervgrklpnlrvLnSYwvgeDgtykyyEvilvDpshkairndkkinwickkvhkhRelrGltsagkksRGlrkkglkgaekirgs 187
                     sl+++aeervgr+  nlrvLnSYw+++D+tykyyEvilvDp+hkair+d++inwi+k+vhkhRe rGlt++gkksRG+ +kg+ ++++  g 
      EEA21640.1  97 SLKSTAEERVGRHAANLRVLNSYWINQDSTYKYYEVILVDPQHKAIRRDPRINWIVKPVHKHRESRGLTATGKKSRGI-QKGHGYTKTNAGR 187
                     ******************************************************************************.99*9999987754 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (203 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       504  (0.0281109); expected 358.6 (0.02)
Passed bias filter:                      339  (0.0189079); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.43
# Mc/sec: 1424.51
//
Query:       EEA21641.1  [L=854]
Description: PSP1 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-27   95.8   2.7    2.5e-27   95.0   2.7    1.5  1  PSP1      PSP1 C-terminal conserved region


Domain annotation for each model (and alignments):
>> PSP1  PSP1 C-terminal conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.0   2.7   1.4e-31   2.5e-27       3      86 .]     626     709 ..     624     709 .. 0.98

  Alignments for each domain:
  == domain 1  score: 95.0 bits;  conditional E-value: 1.4e-31
        PSP1   3 vlrlatpedvstnlenkqdeekalhiaqeklkelnlnmklldaefqfdrkkltfyYvaeervDFreLvkeLfkfyktRIwLcai 86 
                 + rla+++++ t++ ++ +e+ka +++q+k+ e++lnm++ldaefq+d kkltfyY a++ ++F +Lv +Lfk+yktRIw+ ai
  EEA21641.1 626 IKRLAQNHEILTLRDKEGNEAKAKRVCQQKVVEHRLNMEILDAEFQMDWKKLTFYYFADSYINFNSLVTDLFKIYKTRIWMSAI 709
                 88*******************************************************************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (854 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       565  (0.0315132); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.43
# Mc/sec: 6003.63
//
Query:       EEA21642.1  [L=854]
Description: PSP1 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-27   95.8   2.7    2.5e-27   95.0   2.7    1.5  1  PSP1      PSP1 C-terminal conserved region


Domain annotation for each model (and alignments):
>> PSP1  PSP1 C-terminal conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.0   2.7   1.4e-31   2.5e-27       3      86 .]     626     709 ..     624     709 .. 0.98

  Alignments for each domain:
  == domain 1  score: 95.0 bits;  conditional E-value: 1.4e-31
        PSP1   3 vlrlatpedvstnlenkqdeekalhiaqeklkelnlnmklldaefqfdrkkltfyYvaeervDFreLvkeLfkfyktRIwLcai 86 
                 + rla+++++ t++ ++ +e+ka +++q+k+ e++lnm++ldaefq+d kkltfyY a++ ++F +Lv +Lfk+yktRIw+ ai
  EEA21642.1 626 IKRLAQNHEILTLRDKEGNEAKAKRVCQQKVVEHRLNMEILDAEFQMDWKKLTFYYFADSYINFNSLVTDLFKIYKTRIWMSAI 709
                 88*******************************************************************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (854 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       565  (0.0315132); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.73u 0.26s 00:00:00.99 Elapsed: 00:00:00.47
# Mc/sec: 5514.93
//
Query:       EEA21643.1  [L=321]
Description: NifU-related protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      7e-30  102.9   0.1      4e-29  100.5   0.0    2.2  2  Nfu_N     Scaffold protein Nfu/NifU N terminal
    1.1e-27   95.9   0.1    1.9e-27   95.2   0.1    1.4  1  NifU      NifU-like domain


Domain annotation for each model (and alignments):
>> Nfu_N  Scaffold protein Nfu/NifU N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.5   0.0   4.5e-33     4e-29       1      87 []      83     177 ..      83     177 .. 0.92
   2 ?   -0.7   0.0      0.17   1.5e+03      30      53 ..     263     284 ..     251     299 .. 0.66

  Alignments for each domain:
  == domain 1  score: 100.5 bits;  conditional E-value: 4.5e-33
       Nfu_N   1 iqteeTPNpnalkFlpgkellpe...gstaefksaeea.....asplakkLfkiegVksVfigsdFitvtkeddvdWeelkpevlevikeflesg 87 
                 iqte+TPNp+alkFlp++++lpe   +   e+ s +++      spla+kL++ieg++sVf+g+dFitvtk++dv+W+++kpev+++i+e ++sg
  EEA21643.1  83 IQTESTPNPDALKFLPNNRVLPEnfsTPFLEYLSPRSTlapphPSPLAAKLLNIEGISSVFYGPDFITVTKSSDVNWAHVKPEVFSLITEVVTSG 177
                 9*********************9775555999999954457789**********************************************99986 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.17
       Nfu_N  30 ksaeeaasplakkLfkiegVksVf 53 
                 k+    +s l+  + +++gV++V+
  EEA21643.1 263 KNGI--ESMLMHYIEEVQGVQQVL 284
                 3332..477777777777777776 PP

>> NifU  NifU-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.2   0.1   2.1e-31   1.9e-27       1      67 []     215     281 ..     215     281 .. 0.98

  Alignments for each domain:
  == domain 1  score: 95.2 bits;  conditional E-value: 2.1e-31
                 HHHHHHH.HGGG--GG--EEEEEEEETTEEEEEEESGGGG-....THHHHHHHHHHHHH-TT--EEE CS
        NifU   1 ieevleeeirPaLasdGGdielvdvdegvVkvrlqGaCsgCpsstvtlkegiekaLkeevpevkeVe 67 
                 i+e+le++irPa+++dGGdie+ ++++g+V ++l+GaC++C sstvtlk+gie++L+++++ev+ V+
  EEA21643.1 215 IKELLETRIRPAIQEDGGDIEFRGFENGIVLLKLRGACRTCDSSTVTLKNGIESMLMHYIEEVQGVQ 281
                 89*************************************************************9995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (321 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       647  (0.0360868); expected 358.6 (0.02)
Passed bias filter:                      568  (0.0316805); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 2159.38
//
Query:       EEA21644.1  [L=285]
Description: NifU-related protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-29  102.3   0.1    3.2e-29  100.8   0.0    1.8  2  Nfu_N     Scaffold protein Nfu/NifU N terminal
    8.7e-26   89.9   0.0    1.5e-25   89.1   0.0    1.3  1  NifU      NifU-like domain


Domain annotation for each model (and alignments):
>> Nfu_N  Scaffold protein Nfu/NifU N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.8   0.0   3.5e-33   3.2e-29       1      87 []      83     177 ..      83     177 .. 0.92
   2 ?   -3.0   0.0      0.89     8e+03      72      86 ..     262     276 ..     260     277 .. 0.83

  Alignments for each domain:
  == domain 1  score: 100.8 bits;  conditional E-value: 3.5e-33
       Nfu_N   1 iqteeTPNpnalkFlpgkellpe...gstaefksaeea.....asplakkLfkiegVksVfigsdFitvtkeddvdWeelkpevlevikeflesg 87 
                 iqte+TPNp+alkFlp++++lpe   +   e+ s +++      spla+kL++ieg++sVf+g+dFitvtk++dv+W+++kpev+++i+e ++sg
  EEA21644.1  83 IQTESTPNPDALKFLPNNRVLPEnfsTPFLEYLSPRSTlapphPSPLAAKLLNIEGISSVFYGPDFITVTKSSDVNWAHVKPEVFSLITEVVTSG 177
                 9*********************9775555999999954457789**********************************************99986 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.89
       Nfu_N  72 lkpevlevikefles 86 
                 lk+ + ++++++++s
  EEA21644.1 262 LKNGIESMLMHYVSS 276
                 788999999999876 PP

>> NifU  NifU-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.1   0.0   1.7e-29   1.5e-25       1      61 [.     215     275 ..     215     277 .. 0.98

  Alignments for each domain:
  == domain 1  score: 89.1 bits;  conditional E-value: 1.7e-29
                 HHHHHHH.HGGG--GG--EEEEEEEETTEEEEEEESGGGG-....THHHHHHHHHHHHH-T CS
        NifU   1 ieevleeeirPaLasdGGdielvdvdegvVkvrlqGaCsgCpsstvtlkegiekaLkeevp 61 
                 i+e+le++irPa+++dGGdie+ ++++g+V ++l+GaC++C sstvtlk+gie++L+++v+
  EEA21644.1 215 IKELLETRIRPAIQEDGGDIEFRGFENGIVLLKLRGACRTCDSSTVTLKNGIESMLMHYVS 275
                 89*********************************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (285 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       317  (0.0176809); expected 358.6 (0.02)
Passed bias filter:                      289  (0.0161191); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.47
# Mc/sec: 1817.63
//
Query:       EEA21645.1  [L=178]
Description: HIT finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-08   33.7  10.1      4e-08   33.0  10.1    1.4  1  zf-HIT    HIT zinc finger


Domain annotation for each model (and alignments):
>> zf-HIT  HIT zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.0  10.1   2.2e-12     4e-08       3      30 .]       2      30 ..       1      30 [. 0.95

  Alignments for each domain:
  == domain 1  score: 33.0 bits;  conditional E-value: 2.2e-12
                -B-TTT-S.B-SEE-TTT--EESSHHHHH CS
      zf-HIT  3 klCgvCgf.pakYkCpkCntryCSLrCyk 30
                + C+vC +  +kYkCp+C+   CSL C k
  EEA21645.1  2 PTCEVCSKeASKYKCPTCGLLSCSLGCTK 30
                68*************************87 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (178 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       995  (0.0554967); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.23s 00:00:00.66 Elapsed: 00:00:00.39
# Mc/sec: 1357.40
//
Query:       EEA21646.1  [L=570]
Description: Ras guanyl-nucleotide exchange factor RasGEF, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-42  146.0   0.1    2.6e-42  145.0   0.1    1.5  1  RasGEF    RasGEF domain
    4.8e-15   55.7   0.0    1.2e-14   54.4   0.0    1.7  1  RasGEF_N  RasGEF N-terminal motif


Domain annotation for each model (and alignments):
>> RasGEF  RasGEF domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.0   0.1   2.9e-46   2.6e-42       1     176 [.     319     501 ..     319     502 .. 0.92

  Alignments for each domain:
  == domain 1  score: 145.0 bits;  conditional E-value: 2.9e-46
      RasGEF   1 elAeqltlieaelfskikpeellgsa.wsked..rs...pnveaviarfnrlsnwvaseilseeslkkRakviekfikiakecrklnNfnslmailsaL 93 
                 ++A++lt+i++ +f + +p++l++++  s ++  +s   +nv+++i+ fn+l+ +va++il ++++k+Rak++ekf++ia ++r+lnN+nsl a+l+++
  EEA21646.1 319 DFARELTRIDWAMFTSFRPRDLVRHVsLSGAEkgNSkslQNVNRMIQEFNHLAFLVANMILLRDKAKHRAKAMEKFMNIALRLRRLNNYNSLGAVLAGI 417
                 58**********************96333333552246799********************************************************** PP

      RasGEF  94 qsspvsrLkktweavskkslktleeleelmspennfknyrealkssasskpciPflglyltdltfieegnpdtl..egk.iNfeKr 176
                 + +pv+rL +t e ++   +k + +l  lm +++++ +yr a+++s+   + iPfl l+ +dl+  eegn++++  +++ iN++K+
  EEA21646.1 418 NGTPVQRLAQTRELIPLSVQKDFLRLVILMGTQKSHFAYRLAWDNSF--GERIPFLPLHRRDLVSAEEGNKTFVgdNKDrINWKKF 501
                 ****************999***************************5..556***********************95666*****8 PP

>> RasGEF_N  RasGEF N-terminal motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.4   0.0   1.4e-18   1.2e-14       5     105 .]      82     175 ..      80     175 .. 0.83

  Alignments for each domain:
  == domain 1  score: 54.4 bits;  conditional E-value: 1.4e-18
    RasGEF_N   5 gtlekLierLtsk.rll.dddfletFLltyrsFttpaeLlekLieryeinppnnlesdesnswnsksssnirlrvlsvlkewvenhyydfsddkallsk 101
                  t+e+LierL++      d +f  +FL+ yr F  p++Ll++Li r+ +n++ ++  +   +    +    +lr l+v+ +w +++++df  +k ++++
  EEA21646.1  82 VTFEELIERLIALpMSKqDAKFSAIFLCLYRKFAAPSTLLNALITRF-ENTERSDLPQ---L----TRASEQLRLLQVIAQWASEYPEDFAHPK-TRQR 171
                 799*********96333366***************************.5555555555...2....3333799*******************98.9998 PP

    RasGEF_N 102 lekf 105
                 l++f
  EEA21646.1 172 LVDF 175
                 8876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (570 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       541  (0.0301746); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 3984.15
//
Query:       EEA21647.1  [L=126]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.1e-22   78.4   0.9    5.1e-22   78.4   0.9    1.4  2  Complex1_LYR_2  Complex1_LYR-like
    3.7e-05   23.7   2.0    6.5e-05   22.9   2.0    1.4  1  Complex1_LYR    Complex 1 protein (LYR family)
  ------ inclusion threshold ------
      0.058   13.4   0.2       0.08   12.9   0.2    1.3  1  Sigma_1s        Sigma 1s protein
        0.1   12.5   0.1       0.13   12.1   0.1    1.2  1  CHD5            CHD5-like protein


Domain annotation for each model (and alignments):
>> Complex1_LYR_2  Complex1_LYR-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.4   0.9   1.1e-25   5.1e-22       2      82 .]      10     100 ..       9     100 .. 0.91
   2 ?   -3.4   0.2         4   1.8e+04      67      77 ..     111     121 ..     108     122 .. 0.61

  Alignments for each domain:
  == domain 1  score: 78.4 bits;  conditional E-value: 1.1e-25
  Complex1_LYR_2   2 lsLYrrllrelre.....lppelrslgdayvraefrrhk.....hlknpeeialflknqreYaellerynpglkmteeekvrktanrvglq 82 
                     ++LYr+llrel++     ++ ++  +++++ r +f++++      ++++e+++++ k+qr+Ya l+ rynpg++m++ee+vr+ta+rvg++
      EEA21647.1  10 RHLYRALLRELPRrhislSSSTPSNALKRRFRTQFEQSSsptlsSIQQAEQFVQYAKAQRMYATLVARYNPGMDMDQEERVRLTARRVGMD 100
                     89*********87677743677779999999999999668*************************************************86 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 4
  Complex1_LYR_2  67 teeekvrktan 77 
                     +eee +++t+n
      EEA21647.1 111 KEEEILERTKN 121
                     55666777776 PP

>> Complex1_LYR  Complex 1 protein (LYR family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   2.0   1.5e-08   6.5e-05       2      54 ..       8      66 ..       7      69 .. 0.89

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 1.5e-08
  Complex1_LYR  2 qvLsLYRalLRea..rkfpdyn..treyfrrriRdeFrknkh..vtDpekieellkkgr 54
                  ++ +LYRalLRe   r+++  +  +   ++rr R++F++  +  ++++++ e++++ ++
    EEA21647.1  8 RARHLYRALLRELprRHISLSSstPSNALKRRFRTQFEQSSSptLSSIQQAEQFVQYAK 66
                  688*********99777777779999999*************9999********99887 PP

>> Sigma_1s  Sigma 1s protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.2   1.8e-05      0.08       7      48 ..      31      72 ..      25      91 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.8e-05
    Sigma_1s  7 kkSrksRkklkytLllSsgsvrdsiqqkdesvllskvgqpll 48
                + S  ++++ ++   +Ss + ++siqq +++v+++k+  ++ 
  EEA21647.1 31 TPSNALKRRFRTQFEQSSSPTLSSIQQAEQFVQYAKAQRMYA 72
                6688999*****************************987665 PP

>> CHD5  CHD5-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.1   2.8e-05      0.13      52      90 ..      49      87 ..      11      97 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 2.8e-05
        CHD5 52 keelnsisaqDefAkWaKlnRkldkleeeleklkkelsa 90
                   l+si+ +++f ++aK++R +  l + ++   ++ ++
  EEA21647.1 49 SPTLSSIQQAEQFVQYAKAQRMYATLVARYNPGMDMDQE 87
                44689*******************999988766555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (126 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       816  (0.0455129); expected 358.6 (0.02)
Passed bias filter:                      469  (0.0261587); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.44
# Mc/sec: 866.57
//
Query:       EEA21648.1  [L=419]
Description: PP-loop ATPase superfamily protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.8e-20   72.9   0.0    1.1e-19   71.0   0.0    1.8  2  ATP_bind_3      PP-loop family
    4.4e-19   67.7  14.6    8.7e-19   66.7   3.3    3.7  4  zn-ribbon_14    Zinc-ribbon
     0.0094   15.5   1.4     0.0094   15.5   1.4    2.6  3  RecR            RecR protein
  ------ inclusion threshold ------
      0.017   13.9   0.0      0.029   13.2   0.0    1.3  1  tRNA_Me_trans   tRNA methyl transferase
        1.2    9.3   5.8         11    6.3   0.5    2.6  2  zf-UBR          Putative zinc finger in N-recognin (UBR box)
        3.6    7.6   7.6        2.6    8.1   0.6    2.7  3  RNHCP           RNHCP domain


Domain annotation for each model (and alignments):
>> ATP_bind_3  PP-loop family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.0   0.0   3.5e-23   1.1e-19       2     167 ..      54     233 ..      53     247 .. 0.89
   2 ?   -1.1   0.0      0.45   1.3e+03      45      90 ..     316     363 ..     302     370 .. 0.70

  Alignments for each domain:
  == domain 1  score: 71.0 bits;  conditional E-value: 3.5e-23
                 EEEE--SCHHHHHHHHHHHHHCTTTTT..EEEEEEEE-SSSTCHHHHHHHHHHHHHHTT-EEEEEE--H..........HHCTTSTCCCHHHHHHHHHH CS
  ATP_bind_3   2 vlvAvSgGlDSmaLllllaklkkklgi..klvaihvdhglreeskeeaelvkelckklnikleiekvdv..........akkkgknleeaARelRYevl 88 
                 ++++ SgG DS++L  ++++l+++     +lv++ +d g++   ++  e+vk+ +++++++lei   d           a+  +k+  +    +R ++l
  EEA21648.1  54 IAIGASGGKDSTVLASVMKTLNERYDYglNLVLLSIDEGIKGYRDDSLETVKRNAEQYEMPLEIVGYDElygwtmdqvvAQVGKKGNCTYCGVFRRQAL 152
                 789*****************9998877779*************************************99999999888756667777778899****** PP

                 HHCHHCCT.CEEE---BHHHHHHHHHHHHCCT--CCHHH-S-SEEEETTCCEE-..CCCT--HHHHHHHHHHTT---B--C CS
  ATP_bind_3  89 kealkkegievlllAhhadDqaEtfllrlargsglaglagikeaseiasirlvR..PlLkvskeeleeylkekkikwveDe 167
                 ++ + + gi++++++h+adD aEt++++l rg  ++   g++ ++  +s+ + R  Pl   + +e+  y+++kk++++  e
  EEA21648.1 153 DRGAARLGIKHIVTGHNADDVAETVMMNLLRGDLPRLSRGTSIVTGQDSTDMKRskPLKYAYEKEIVLYAHHKKLDYFSTE 233
                 ***********************************999999988877775554444*********************9765 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.45
                 HHHHHHHHHHHHTT-EEEEEE--H..HHCTTSTCCCHHHHHHHHHHHH CS
  ATP_bind_3  45 eeaelvkelckklnikleiekvdv..akkkgknleeaARelRYevlke 90 
                 e++ + +e ++ ++i+++  +v+   ++kk  +++ +  ++R +v+ +
  EEA21648.1 316 EKQLAANEAAEDHEIEITLPTVNDskKTKKPAQVQVKGKTIRAQVIGK 363
                 445556677888889998888888555555677888888888887755 PP

>> zn-ribbon_14  Zinc-ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.6   0.4    0.0036        11      12      19 ..      23      30 ..      22      31 .. 0.86
   2 ?    1.2   0.2      0.09   2.7e+02       1       8 [.     139     146 ..     139     152 .. 0.82
   3 ?   -2.8   0.0       1.5   4.6e+03      19      29 ..     247     257 ..     247     258 .. 0.86
   4 !   66.7   3.3   2.9e-22   8.7e-19       1      31 [.     362     392 ..     362     393 .. 0.96

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0036
  zn-ribbon_14 12 qkiCkACv 19
                  +k+CkAC 
    EEA21648.1 23 HKLCKACF 30
                  79*****6 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.09
  zn-ribbon_14   1 gkCerCGy 8  
                   g+C+ CG 
    EEA21648.1 139 GNCTYCGV 146
                   79*****7 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 1.5
  zn-ribbon_14  19 vLLegLnkgrp 29 
                   +L+++L+k rp
    EEA21648.1 247 TLIKDLEKIRP 257
                   699****9988 PP

  == domain 4  score: 66.7 bits;  conditional E-value: 2.9e-22
  zn-ribbon_14   1 gkCerCGylSSqkiCkACvLLegLnkgrpkl 31 
                   gkCerCGy+SSqk+CkAC+LL+gLnk+rpk+
    EEA21648.1 362 GKCERCGYISSQKVCKACTLLDGLNKNRPKT 392
                   79****************************7 PP

>> RecR  RecR protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.5      0.44   1.3e+03      12      23 ..      19      30 ..      14      31 .. 0.76
   2 ?   -2.6   0.1       1.5   4.3e+03      18      25 ..     140     147 ..     138     151 .. 0.69
   3 !   15.5   1.4   3.1e-06    0.0094      16      35 ..     361     380 ..     358     381 .. 0.91

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.44
                HHHH-EE-TTT- CS
        RecR 12 akekvrhCsrCg 23
                 k++ + C+ C+
  EEA21648.1 19 RKNRHKLCKACF 30
                577889999997 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.5
                 E-TTT--E CS
        RecR  18 hCsrCgnl 25 
                  C  Cg +
  EEA21648.1 140 NCTYCGVF 147
                 57778765 PP

  == domain 3  score: 15.5 bits;  conditional E-value: 3.1e-06
                 -EE-TTT--EESSSS-CCCC CS
        RecR  16 vrhCsrCgnlteedlCaICs 35 
                 ++ C+rCg ++ + +C  C+
  EEA21648.1 361 IGKCERCGYISSQKVCKACT 380
                 899****************6 PP

>> tRNA_Me_trans  tRNA methyl transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   9.7e-06     0.029       2     131 ..      53     175 ..      52     198 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 9.7e-06
  tRNA_Me_trans   2 kvvvalSgGVDSsvaaallkeqgyev.igvflklweeedeegkeccaeedlkdaervaeklgiplevvdfekeykekvfeefleeyeeGrTPnPdv 96 
                    +++++ SgG DS+v a ++k+       g+ l l +  de   +   ++ l++++r ae+ ++ple+v + + y  ++ + + +  ++G+    + 
     EEA21648.1  53 RIAIGASGGKDSTVLASVMKTLNERYdYGLNLVLLSI-DEGI-KGYRDDSLETVKRNAEQYEMPLEIVGYDELYGWTMDQVVAQVGKKGN----CT 142
                    7999************999865433313444444433.3333.5688999************************8776555555556665....88 PP

  tRNA_Me_trans  97 lCNkeiKfgallekakeelgadalatGHYarvsle 131
                     C    + +al + a + lg++ ++tGH a  + e
     EEA21648.1 143 YCGVF-RRQALDRGAAR-LGIKHIVTGHNADDVAE 175
                    89754.44455555555.99999999999987766 PP

>> zf-UBR  Putative zinc finger in N-recognin (UBR box)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.6     0.011        32      15      34 ..       6      33 ..       4      51 .. 0.78
   2 ?    6.3   0.5    0.0037        11       9      31 ..     358     380 ..     348     386 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.011
      zf-UBR 15 CltCsld........etsviCeeCfkas 34
                C++C+ +        + + +C++Cf++ 
  EEA21648.1  6 CFNCQASraviirrkNRHKLCKACFIEI 33
                8888888888999987799******874 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0037
      zf-UBR   9 gevvyrCltCsldetsviCeeCf 31 
                  +v+ +C+ C+  +++ +C++C 
  EEA21648.1 358 AQVIGKCERCGYISSQKVCKACT 380
                 488999****************6 PP

>> RNHCP  RNHCP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.2     0.028        84      26      50 ..       6      30 ..       3      45 .. 0.80
   2 ?   -4.1   0.1       5.3   1.6e+04      69      78 ..     141     150 ..     139     153 .. 0.70
   3 ?    8.1   0.6   0.00088       2.6      50      82 ..     344     377 ..     335     382 .. 0.79

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.028
       RNHCP 26 CpsCLlskHvdeepgdraseCkglm 50
                C +C +s+ v ++  +r++ Ck+ +
  EEA21648.1  6 CFNCQASRAVIIRRKNRHKLCKACF 30
                8899999999999999999999876 PP

  == domain 2  score: -4.1 bits;  conditional E-value: 5.3
       RNHCP  69 CekCgelkkn 78 
                 C+ Cg ++++
  EEA21648.1 141 CTYCGVFRRQ 150
                 8888877665 PP

  == domain 3  score: 8.1 bits;  conditional E-value: 0.00088
       RNHCP  50 mepiavevkkkk.ewvivhrCekCgelkknrvak 82 
                  +p +v+vk k  + +++ +Ce+Cg +++++v+k
  EEA21648.1 344 KKPAQVQVKGKTiRAQVIGKCERCGYISSQKVCK 377
                 5788888876543789*************99976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (419 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       920  (0.0513135); expected 358.6 (0.02)
Passed bias filter:                      622  (0.0346924); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.46
# Mc/sec: 2721.20
//
Query:       EEA21649.1  [L=229]
Description: C-8 sterol isomerase (Erg-1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.9e-99  331.2   0.3    2.3e-99  331.0   0.3    1.0  1  ERG2_Sigma1R  ERG2 and Sigma1 receptor like protein


Domain annotation for each model (and alignments):
>> ERG2_Sigma1R  ERG2 and Sigma1 receptor like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  331.0   0.3  1.3e-103   2.3e-99       2     209 .]      23     228 ..      22     228 .. 0.98

  Alignments for each domain:
  == domain 1  score: 331.0 bits;  conditional E-value: 1.3e-103
  ERG2_Sigma1R   2 llllllvalvylldklleknyifdpkelqelakkaiakhendtkavleeivkelkkeypdelinlleeeewvfnnaGgamGamlilhaSitEYlilF 98 
                   +ll++++ l+y+l++ le++yifdp++l++l+++aia+h ndt+av+++iv el ++   +++n +  eewvfnnaGgamGam+i+haSitEYli+F
    EEA21649.1  23 VLLAVFASLFYYLEQHLESFYIFDPAHLHDLSQRAIAAHGNDTRAVVKYIVGELDEKLDGKHLNFE--EEWVFNNAGGAMGAMYIIHASITEYLIIF 117
                   678999******************************************************987766..9**************************** PP

  ERG2_Sigma1R  99 GtavgteGhtGrhladdyftiLkGeqlaakpgelekevYkpGdvhhlkrgeakqykmeegcfaLeyarGwipsmlpFgfadtlsstlDfvtlyktvr 195
                   Gta+gteGhtGrh+addyf+iL+G+qla+ pge+e+evY++G+vhhl+rg++kqykm+e+cfaLeyarGwip+ml Fg+adt++stlDf+tl+ t+r
    EEA21649.1 118 GTAIGTEGHTGRHTADDYFHILQGTQLAYVPGEYEPEVYPQGSVHHLRRGDVKQYKMDESCFALEYARGWIPPMLGFGYADTFTSTLDFPTLWATTR 214
                   ************************************************************************************************* PP

  ERG2_Sigma1R 196 itaremiknllkgk 209
                   it+remi nll+gk
    EEA21649.1 215 ITGREMIGNLLQGK 228
                   ***********997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (229 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       409  (0.0228122); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 1555.95
//
Query:       EEA21650.1  [L=433]
Description: cyclin (Pcl1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.7e-11   43.3   0.0    6.5e-11   42.1   0.0    1.7  1  Cyclin_N    Cyclin, N-terminal domain
    1.7e-06   28.5   0.0    4.6e-06   27.1   0.0    1.7  1  Cyclin      Cyclin
  ------ inclusion threshold ------
       0.12   12.2   1.0       0.19   11.5   1.0    1.3  1  DASH_Spc34  DASH complex subunit Spc34


Domain annotation for each model (and alignments):
>> Cyclin_N  Cyclin, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.1   0.0   1.1e-14   6.5e-11      37     126 ..      84     183 ..      79     184 .. 0.90

  Alignments for each domain:
  == domain 1  score: 42.1 bits;  conditional E-value: 1.1e-14
                 HHHHHHHHTT--TTHHHHHHHHHHHHHHHS.---CC...CHHHHHHHHHHHHHHHHSSS---HHHHHHHT......TTSS-HHHHHHHHHHHHHHTTT- CS
    Cyclin_N  37 wlvevaekfkltpetlflavnyldRflskk.svpkd...klqlvgatcLllAaKveeisppkledlvyit......deafteeeilemErliLetLnfd 125
                 ++  ++++ +++  tl++++++l R+ ++   v k    +++++++++L+lAaK  ++s+pk ++++ +t      +  f+  e++ mEr++L  L++d
  EEA21650.1  84 FISSIVHRSQVQVPTLMTSLVFLARLRARLpPVAKGmrcTVHRIFLASLILAAKNLNDSSPKNKHWARYTavrgypGFGFSLAEVNLMERQLLFLLDWD 182
                 7889999*******************9965467666777*******************************887764339*******************9 PP

                 - CS
    Cyclin_N 126 l 126
                  
  EEA21650.1 183 T 183
                 6 PP

>> Cyclin  Cyclin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.1   0.0   7.7e-10   4.6e-06      81     160 ..      96     182 ..      73     183 .. 0.82

  Alignments for each domain:
  == domain 1  score: 27.1 bits;  conditional E-value: 7.7e-10
                 HHHHHHHHHHHHHHHH..H-TT---STTTHHHHHHHHHHHHHHHH-SS---HHHHHHHH........TS-HHHHHHHHHHHHHHTTT- CS
      Cyclin  81 plvllgtliYldrivkrcvsealvvtsanihRllivallvatKflvDlsysnekfakvg........gislkELnkLEidFlflvdFd 160
                    l+++l++l r+  r    a      ++hR+ +++l  a K l+D+s +n+++a+ +        g sl+E+n +E + lfl+d+d
  EEA21650.1  96 VPTLMTSLVFLARLRARLPPVA-KGMRCTVHRIFLASLILAAKNLNDSSPKNKHWARYTavrgypgfGFSLAEVNLMERQLLFLLDWD 182
                 556999********99655555.455689*************************9999833333334458****************98 PP

>> DASH_Spc34  DASH complex subunit Spc34
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   1.0   3.2e-05      0.19     164     221 ..     198     256 ..     173     275 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 3.2e-05
  DASH_Spc34 164 leelltkyplleake.kieelreeYeelseeieeleaeiaeQkkqLeaqnknesessse 221
                 l  + ++y+++e+ke   +++++++  l+++ e+l a+ + Qk+++ ++  + s++ s+
  EEA21650.1 198 LAPIRRQYEIAEQKEaMAQQHHHDWWRLNASAESLAARLRRQKQEMRGEVGSLSQRRSQ 256
                 566889*********55678999***********************9987666554433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (433 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       731  (0.0407719); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.42
# Mc/sec: 3070.13
//
Query:       EEA21651.1  [L=531]
Description: siderophore biosynthesis protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.8e-46  157.4   0.0    2.8e-46  156.8   0.0    1.2  1  Acetyltransf_8  Acetyltransferase (GNAT) domain


Domain annotation for each model (and alignments):
>> Acetyltransf_8  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  156.8   0.0   1.6e-50   2.8e-46       4     145 .]     368     511 ..     366     511 .. 0.96

  Alignments for each domain:
  == domain 1  score: 156.8 bits;  conditional E-value: 1.6e-50
                     GGHHHHHHHCTSCCCHHHH-----HHHHHHHHHHHC.STTEEEEEEEETTEEEEEEEEEEGGGCGGGGCS.---TT-EEEEEEESSHHHCTTTCH CS
  Acetyltransf_8   4 aDlellhrWmnrprvaewweeagtleevrellakldadphsepliglldgepvgyfeiYwakedelaeyy.daepgdrGiHlligeaeargkglt 97 
                     +Dl+llh+Wmn prv++ w+eag++ + + +l++  +++hs+p+ g+++g+p+gyfeiYw+ked+ ++   ++ ++drG+H+l+ge e+rg +++
      EEA21651.1 368 SDLDLLHKWMNVPRVNAAWGEAGSKSKIEGFLKQGLNSRHSFPVFGCWNGRPFGYFEIYWVKEDRFGRLLnNVGNYDRGLHVLVGEDEFRGSHRV 462
                     6****************************99998888*****************************887559*********************** PP

                     HHHHHHHHHHHH.CCTT--EEEE--BTT-HHHHHHHHHTT-EEEEEEEE CS
  Acetyltransf_8  98 tallralvhylf.adprtrrvvvEPdvrNerairllekaGfekekevdl 145
                       +l++lvhy++ adprt+ v++EP+v+N+++i++l ++Gf ke+ev +
      EEA21651.1 463 HLWLSSLVHYCWlADPRTETVLLEPRVDNQKLISYLMQLGFYKEGEVAF 511
                     ************66********************************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (531 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       394  (0.0219756); expected 358.6 (0.02)
Passed bias filter:                      353  (0.0196888); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.24s 00:00:00.79 Elapsed: 00:00:00.42
# Mc/sec: 3832.07
//
Query:       EEA21652.1  [L=502]
Description: proline utilization protein PrnX-like, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.3e-15   55.8   0.0    6.3e-14   51.6   0.0    2.6  2  OCD_Mu_crystall  Ornithine cyclodeaminase/mu-crystallin famil
    8.8e-07   29.1   0.0    5.5e-05   23.2   0.0    2.7  2  Shikimate_DH     Shikimate / quinate 5-dehydrogenase
  ------ inclusion threshold ------
      0.052   12.3   0.7      0.079   11.7   0.7    1.2  1  Herpes_LMP2      Gammaherpesvirus latent membrane protein (LM


Domain annotation for each model (and alignments):
>> OCD_Mu_crystall  Ornithine cyclodeaminase/mu-crystallin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0     0.032   1.9e+02      20      72 ..      26      82 ..       8      95 .. 0.77
   2 !   51.6   0.0     1e-17   6.3e-14      95     240 ..     218     384 ..     204     444 .. 0.80

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.032
                     CHHHHHHHHHHHHCC.......-CE----EEEEECCGTEEEE.EEEEEETTTTEEEEEEEE CS
  OCD_Mu_crystall 20 lakaveeafrrlasg.......kvkkpprvalevkdsrgele.vmpaylagrellgvKlvn 72
                     l + + +a+r+++ g       +  +p r+a   +d  g+    mpa+ ++  ++gvK+  
       EEA21652.1 26 LQHNLADALREYSTGsqeqgcsASYQPHRTAITGND--GKTTiFMPASTGK--TTGVKILS 82
                     555667888888888777777556677778888777..444316*****99..9****976 PP

  == domain 2  score: 51.6 bits;  conditional E-value: 1e-17
                      TT--EEEEEE-HHHHHHHHHHHHHHHHHHHS-TT--EEEEE--SHHHHHHHHHHCCCS-..-SEEEEE-SSHHHHHHH......HHHCCS..CT CS
  OCD_Mu_crystall  95 etGvplalmdatlltalRTaAvsavaakyLarkdasvlaiiGaGvqaetqlealkavld..ikevriydrdeeaaekf......aenlqe.fef 179
                      + G p+ l++a  lta RTa +s +   + +rk  ++++++GaG+qa+ +++    +++  +k+v i +r+   ++ +      aen++   ++
       EEA21652.1 218 QDGLPIGLISAQDLTAFRTALTSLLI--FNKRKHVKTITVFGAGRQAYWHIRLALLLRGpeVKRVYIINRSFDRTAELlrdiyaAENASWrSDV 309
                      679********************875..789*****************9998777777668******999988877761221213445544477 PP

                      T-EEECS........CHHHHTTSSEEEE----SS-SB-GGGS-......TT-EEEE-S--STT--SB-HHHHHCC CS
  OCD_Mu_crystall 180 evsacks........eeeavegadivvtvTaakapilkaewvk......pGahinavgadapgkteLdddilkra 240
                      + +a +s         +eav +ad++  +T++ +p++ ae++        G +i a+g+  ++ teL++dilk+ 
       EEA21652.1 310 KFHAFSSdfveynrlSREAVRKADVIFCCTPSLEPLFPAEFLTstegrrKGRLIVAIGSYKSHMTELHPDILKNE 384
                      77887774444444469************************9633333369*********************985 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.2   0.0   9.2e-09   5.5e-05      11     111 ..     249     366 ..     241     368 .. 0.69
   2 ?   -2.0   0.0      0.56   3.3e+03      63      99 ..     404     440 ..     395     445 .. 0.80

  Alignments for each domain:
  == domain 1  score: 23.2 bits;  conditional E-value: 9.2e-09
                   TT-EEEEES-SHHHH...HHHHHHHCCT-CEEEEEESSHHHHHHHHHHH.T.ET.............-EEEEGCGHH.HHHHT-SEEEE-SSSSS-S CS
  Shikimate_DH  11 kekkvlliGaGemae...lvakhLlakgvkkvvvaNRtlerakelaeel.kgee.............iealkleelk.ellaeadvvisataseepi 89 
                   + k++++ GaG+ a    ++a  L   +vk+v ++NR+++r +el +++  +e+             + +++++ l+ e++++adv++++t s ep+
    EEA21652.1 249 HVKTITVFGAGRQAYwhiRLALLLRGPEVKRVYIINRSFDRTAELLRDIyAAENaswrsdvkfhafsSDFVEYNRLSrEAVRKADVIFCCTPSLEPL 345
                   56899*******9972223455677889***************99876632222111111111111134556666643789**************** PP

                   B-HHHHHCCHHH.S..EEEEE- CS
  Shikimate_DH  90 lekeeveealkkrkkplllvDi 111
                   + +e ++++  +r k +l+v i
    EEA21652.1 346 FPAEFLTSTEGRR-KGRLIVAI 366
                   ****999988665.66666655 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.56
                   EEEGCGHHHHHHT-SEEEE-SSSSS-SB-HHHHHCCH CS
  Shikimate_DH  63 alkleelkellaeadvvisataseepilekeeveeal 99 
                   ++ +++l+ +l+ea  ++ a   ++ ++e +e++ ++
    EEA21652.1 404 VVLVDSLEMCLQEAGEIVQAGLGPHQLVEIGELMIMK 440
                   6778999999999999999999999999888877665 PP

>> Herpes_LMP2  Gammaherpesvirus latent membrane protein (LMP2) protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.7   1.3e-05     0.079      18     105 ..     141     230 ..     127     236 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 1.3e-05
                  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSXXXXXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Herpes_LMP2  18 gdpdgydggnnsqypsasgssgntptppndeeresneeppppyedpywgngdrhs..dyqplgtqdqslylglqhdgndglppppysprd 105
                   d  g  gg++s+  s s ss    +p  + +  s +        py g  ++ s   + p+g++d s    l   g+dglp    s +d
   EEA21652.1 141 DDDAGSVGGDDSEVESGSFSSSTGGAPSINHQSLSSQSDSLRASKPYMGSVQHISgkAWPPMGARDSSPRGTLTLVGQDGLPIGLISAQD 230
                  3456899**************999999999999999999999********9988733578**********************98888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (502 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       525  (0.0292822); expected 358.6 (0.02)
Passed bias filter:                      395  (0.0220313); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.45
# Mc/sec: 3375.44
//
Query:       EEA21653.1  [L=411]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (411 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       610  (0.0340231); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2782.28
//
Query:       EEA21654.1  [L=481]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.9e-23   81.4   0.2    8.8e-23   80.3   0.2    1.6  1  DUF1992   Domain of unknown function (DUF1992)


Domain annotation for each model (and alignments):
>> DUF1992  Domain of unknown function (DUF1992)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.3   0.2   4.9e-27   8.8e-23       1      70 []     172     243 ..     172     243 .. 0.97

  Alignments for each domain:
  == domain 1  score: 80.3 bits;  conditional E-value: 4.9e-27
     DUF1992   1 laEerIreAierGeFdnlpg.rGKPLpldd.endplvpeeerlanrilknagvlPpeielrkeieelkellr 70 
                 la+erI++Ai+rG+F+nlp+ +GK    d+ +n+++++++e+++n+i+++++++Pp+ie+++++++++ ++r
  EEA21654.1 172 LANERIEDAIARGQFKNLPRgKGKHTTTDHnANSAFIDTTEYFMNKIIQKQEIVPPWIEKQQDLAREIGRFR 243
                 79**************************889***********************************998886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (481 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       589  (0.0328518); expected 358.6 (0.02)
Passed bias filter:                      429  (0.0239277); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.48
# Mc/sec: 3027.08
//
Query:       EEA21655.1  [L=101]
Description: 37S ribosomal protein Mrp10, mitochondrial [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.053   13.5   0.2      0.067   13.2   0.2    1.2  1  Cmc1      Cytochrome c oxidase biogenesis protein Cmc1 like


Domain annotation for each model (and alignments):
>> Cmc1  Cytochrome c oxidase biogenesis protein Cmc1 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.2   3.7e-06     0.067       7      51 ..      28      71 ..      24      85 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 3.7e-06
        Cmc1  7 kkarkeCaelikalaeChkdrllkvvgkCneekeamkkClkeyrt 51
                ++ +++Ca ++  + +C + +  +    C  + e +k+C+   r 
  EEA21655.1 28 QQQQNSCATIMSSMLNCWA-SAGQGNEGCSGLEESLKACMDGRRD 71
                67789**************.9******************976654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (101 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       552  (0.0307881); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.36u 0.25s 00:00:00.61 Elapsed: 00:00:00.38
# Mc/sec: 798.84
//
Query:       EEA21656.1  [L=231]
Description: phosphoglycerate mutase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    3.9e-35  121.3   0.0    5.1e-35  120.9   0.0    1.1  1  His_Phos_1  Histidine phosphatase superfamily (branch 1)


Domain annotation for each model (and alignments):
>> His_Phos_1  Histidine phosphatase superfamily (branch 1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  120.9   0.0   2.9e-39   5.1e-35       1     185 [.      11     215 ..      11     221 .. 0.86

  Alignments for each domain:
  == domain 1  score: 120.9 bits;  conditional E-value: 2.9e-39
                 EEEEE---BTTB--....TT----B-HHHHHHHHHHHHHHTT.......S---EEEE-SSHHHHHHHHHHHHCTT...--EEE-GGGS----GGGTT-B CS
  His_Phos_1   1 lyLvRHGetewnaegrlqgrtdvpLteeGreqAealaerlag.......epidaiysSplkRarqTaeliaealg...lpveldegLrEidfGdweglt 89 
                 ++++RHGetew ++g + g t  +Lt++G++q++  ++ l g        +i+++y+Sp kRa++T el+         +v ++++L E+ +G++eg+ 
  EEA21656.1  11 VFIARHGETEWTKSGQYTGITELELTPHGETQVQNSGRVLVGpgklidpSRIAHVYVSPRKRAQKTHELLFSSPLepaDKVSTTDRLAEWGYGEYEGMV 109
                 5799***********************************8777766444666666*************987754458899******************9 PP

                 .HHHHHH..HSHHHHHHHHH-GGG-B...S-BHHHHHHHHHHHHHHHHHHTTTSE........EEEEE-HHHHHHHHHHHHT--GGGGGGB---TT-EE CS
  His_Phos_1  90 taeiaeeypeeleawlrdpadvrppg...gEsledvaaRvaaaleelaarheget........vlvVsHggvirallarllglpleelrrleldnasls 177
                 t++i++  ++e++   ++p+d +  g   gEs ++v++R+++ ++e++a + ++         +++++Hg+++ra+++r+lg+p+e++  l l++ ++ 
  EEA21656.1 110 TSQIRAL-RKEHGLDTERPWDIWRDGcegGESAQQVTDRLDDLIKEIRAFQVNHMhgepgpadIVLIAHGHLLRAFVKRWLGYPMEFPLSLMLEPGGIG 207
                 9999987.666777777777788887888****************776644443334455667************************************ PP

                 EEEE-SS- CS
  His_Phos_1 178 vlefdegg 185
                 vl++++++
  EEA21656.1 208 VLSYQHHN 215
                 ****9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (231 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       304  (0.0169558); expected 358.6 (0.02)
Passed bias filter:                      298  (0.0166211); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.40
# Mc/sec: 1723.86
//
Query:       EEA21657.1  [L=210]
Description: phosphoglycerate mutase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.5e-33  116.1   0.0    1.8e-33  115.8   0.0    1.1  1  His_Phos_1  Histidine phosphatase superfamily (branch 1)


Domain annotation for each model (and alignments):
>> His_Phos_1  Histidine phosphatase superfamily (branch 1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.8   0.0     1e-37   1.8e-33       1     179 [.      11     209 ..      11     210 .] 0.85

  Alignments for each domain:
  == domain 1  score: 115.8 bits;  conditional E-value: 1e-37
                 EEEEE---BTTB--....TT----B-HHHHHHHHHHHHHHTT.......S---EEEE-SSHHHHHHHHHHHHCTT...--EEE-GGGS----GGGTT-B CS
  His_Phos_1   1 lyLvRHGetewnaegrlqgrtdvpLteeGreqAealaerlag.......epidaiysSplkRarqTaeliaealg...lpveldegLrEidfGdweglt 89 
                 ++++RHGetew ++g + g t  +Lt++G++q++  ++ l g        +i+++y+Sp kRa++T el+         +v ++++L E+ +G++eg+ 
  EEA21657.1  11 VFIARHGETEWTKSGQYTGITELELTPHGETQVQNSGRVLVGpgklidpSRIAHVYVSPRKRAQKTHELLFSSPLepaDKVSTTDRLAEWGYGEYEGMV 109
                 5799***********************************8777766444666666*************987754458899******************9 PP

                 .HHHHHH..HSHHHHHHHHH-GGG-B...S-BHHHHHHHHHHHHHHHHHHTTTSE........EEEEE-HHHHHHHHHHHHT--GGGGGGB---TT-EE CS
  His_Phos_1  90 taeiaeeypeeleawlrdpadvrppg...gEsledvaaRvaaaleelaarheget........vlvVsHggvirallarllglpleelrrleldnasls 177
                 t++i++  ++e++   ++p+d +  g   gEs ++v++R+++ ++e++a + ++         +++++Hg+++ra+++r+lg+p+e++  l l++ ++ 
  EEA21657.1 110 TSQIRAL-RKEHGLDTERPWDIWRDGcegGESAQQVTDRLDDLIKEIRAFQVNHMhgepgpadIVLIAHGHLLRAFVKRWLGYPMEFPLSLMLEPGGIG 207
                 9999987.666777777777788887888****************776644443334455667************************999999888877 PP

                 EE CS
  His_Phos_1 178 vl 179
                 vl
  EEA21657.1 208 VL 209
                 66 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (210 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       423  (0.0235931); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.24s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1527.03
//
Query:       EEA21658.1  [L=467]
Description: cytochrome P450 monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.8e-46  157.2   0.0    8.3e-46  156.7   0.0    1.1  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  156.7   0.0   4.6e-50   8.3e-46      85     448 ..      53     450 ..      29     462 .. 0.78

  Alignments for each domain:
  == domain 1  score: 156.7 bits;  conditional E-value: 4.6e-50
                 SSSTTCGHHHHHHHHHHHHHHHTSH...STTTHHHHHH..HHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHT..TTSSHHHHHHHH CS
        p450  85 kgvlfangekwkklRrfltptltsf...gklsleelve..eeaedlveklrkkagesselditellskaaldvigsilFgarfdl..ledeklselvka 176
                  ++++++g+k + +R++++ ++ s+   ++ +  +l+    + ++l+  l++ a++++ +d++el s  ++d+++  l+g +  +  l+d     + k 
  EEA21658.1  53 VSMFTMTGSKEHATRKRMLSNIYSKsylQSSPALKLISttMIYDRLLPILETAASSKEAVDVHELNSALTMDFVSAYLYGLQNATnlLQDVP---FRKH 148
                 57899999999999***99999999986555555555411455889999999999999********************99875540044444...3444 PP

                 HHHHHH......HHHCHHHHCCCCCH.HHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHC.........SCSSCSHHHHHHHHC..TTCTCT.S CS
        p450 177 veelss......llskssvqllllfp.llkylptkllrklkeavkklkdlldklieerretldsa.........kksrrdfldalllak..kekkge.s 256
                   ++++      +  ++++ l+ + + + +++   + + +++a+++++d  + l  + +++l s+         k+ ++++++ + l k   + + +  
  EEA21658.1 149 LLHNYQcrkpfeFYYQEVPGLVTFSQaIGLPI---IPQWCRDATQVMDDWNMDLCDKAEKSLASSdprieptvyKQMKVSMIKQMNLGKedMAANSQrL 244
                 44443411222122233333333333333333...344455555666666666666666666666777*999998888999999988888633444456 PP

                 SSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHC.CTTT.........T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEE CS
        p450 257 klsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklreEidevl.gdkr.........eptyddlqklpyldavikEtLRlhpvvplllpRe 345
                 k ++ ++a ++ + l+aG++T++ +l++   eL k+ ++q++lr+E+++   + ++          p  +++  lp+l+avi EtLRlh ++p   pR 
  EEA21658.1 245 KQQKIDIACETYDQLTAGHETSAVGLTYLYWELSKHTDIQDELRNELHTLStRINKaptseaakqLPGAKEIDALPLLQAVIMETLRLHAPIPGIQPRI 343
                 7788899******************************************9955555889999998999999**********************9999** PP

                 SSS.CEEETT.EEE-TT-EEEEEHHHHHT-TTTSSSTTS--GGGGB-TTS..CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTS CS
        p450 346 vtk.dvvirg.ylipkGtevivnlyalhrdpevfpnPeeFdpeRFldekg..nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpe 440
                 ++k   ++ g ++ip + +v   +y+lhr+p+vfp+Pe+ +p R+l+e +  + +     f +FG G R+C+G ++A+ e+kl+ + +  n++ ++ ++
  EEA21658.1 344 TPKpSSTLVGyHNIPPNVRVNAQAYSLHRNPDVFPEPESWQPRRWLKEYNspEMEEMRRWFWAFGSGGRMCVGSNFAIQEMKLVTTAIYTNYKTTIVDD 442
                 ***7667888789***********************************999855678899***********************************9999 PP

                 TSGGEEES CS
        p450 441 tdpppile 448
                 + ++ i+ 
  EEA21658.1 443 EGIEAIDA 450
                 98888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (467 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       486  (0.0271069); expected 358.6 (0.02)
Passed bias filter:                      381  (0.0212505); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.47
# Mc/sec: 2965.57
//
Query:       EEA21659.1  [L=592]
Description: F-box domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      1e-05   25.3   0.1      1e-05   25.3   0.1    2.2  2  F-box-like  F-box-like
    0.00055   19.8   0.0     0.0015   18.3   0.0    1.7  1  F-box       F-box domain
  ------ inclusion threshold ------
       0.03   14.2   0.0      0.066   13.1   0.0    1.5  1  F-box_4     F-box


Domain annotation for each model (and alignments):
>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.3   0.1   1.7e-09     1e-05       2      43 ..       3      45 ..       2      48 .. 0.89
   2 ?   -2.8   1.8       1.1   6.4e+03      29      43 ..     576     588 ..     576     590 .. 0.73

  Alignments for each domain:
  == domain 1  score: 25.3 bits;  conditional E-value: 1.7e-09
  F-box-like  2 srLPdEiLlqIFsyLpps.dLlrlalVCrrWrrvaldtplLWr 43
                ++LP Ei+  I  yLp+  +L+ l+++C r + ++  + +++r
  EEA21659.1  3 ADLPSEIIYNIATYLPTVnSLTHLSQTCHRLHKIITADDRVYR 45
                79*************7555****************88778887 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1.1
  F-box-like  29 rrWrrvaldtplLWr 43 
                 rrWrr+   + + Wr
  EEA21659.1 576 RRWRRL-D-ENQSWR 588
                 89**99.3.447777 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   2.5e-07    0.0015       4      41 ..       3      41 ..       2      47 .. 0.92

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 2.5e-07
                HHS-HHHHHHHHHTS-HHH.HHHHCTT-HHHHHHHTTHH CS
       F-box  4 srLPsevlrhILerLplsd.llalrrVSkgwrilidsdr 41
                 +LPse++ +I  +Lp++  l  l++++ +++++i  d 
  EEA21659.1  3 ADLPSEIIYNIATYLPTVNsLTHLSQTCHRLHKIITADD 41
                69********************************98765 PP

>> F-box_4  F-box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   1.1e-05     0.066       5      38 ..       2      36 ..       1      40 [. 0.90

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.1e-05
     F-box_4  5 LssLPlevlqhiaslLDsf.sLsqLslvskllrev 38
                L +LP e++ +ia++L  + sL++Ls+++++l ++
  EEA21659.1  2 LADLPSEIIYNIATYLPTVnSLTHLSQTCHRLHKI 36
                789*************98659**********9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (592 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       362  (0.0201908); expected 358.6 (0.02)
Passed bias filter:                      286  (0.0159518); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 3803.66
//
Query:       EEA21660.1  [L=416]
Description: ribosome assembly and transport protein Srp40, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.4e-16   59.2   0.2    5.4e-16   59.2   0.2    2.5  3  SRP40_C     SRP40, C-terminal domain


Domain annotation for each model (and alignments):
>> SRP40_C  SRP40, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.7   2.6         1   1.8e+04      53      65 ..     123     135 ..     121     143 .. 0.48
   2 ?   -4.1   0.3         1   1.8e+04      12      23 ..     316     327 ..     311     330 .. 0.50
   3 !   59.2   0.2     3e-20   5.4e-16      21      76 .]     363     414 ..     350     414 .. 0.85

  Alignments for each domain:
  == domain 1  score: -4.7 bits;  conditional E-value: 1
     SRP40_C  53 KnKkKrgsyrgge 65 
                 K+K K +s + ++
  EEA21660.1 123 KKKSKSSSSSSSS 135
                 5555555544443 PP

  == domain 2  score: -4.1 bits;  conditional E-value: 1
     SRP40_C  12 evadkrladnsy 23 
                 + ++k+ ad s+
  EEA21660.1 316 KSQKKKDADTSF 327
                 333444455555 PP

  == domain 3  score: 59.2 bits;  conditional E-value: 3e-20
     SRP40_C  21 nsyeakkgaeddyGekanedLiktrGkgFrkeKnKkKrgsyrggeIdte.svnSikF 76 
                 n+y      + +y+++a +dL++trGkgF+keKnKkKrgsyrgg Id+  s  S+kF
  EEA21660.1 363 NTYV-----AYAYADRAFKDLSVTRGKGFTKEKNKKKRGSYRGGPIDIGpSKYSFKF 414
                 5555.....458********************************9998535678888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (416 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2297  (0.128116); expected 358.6 (0.02)
Passed bias filter:                      721  (0.0402142); expected 358.6 (0.02)
Passed Vit filter:                       381  (0.0212505); expected 17.9 (0.001)
Passed Fwd filter:                       209  (0.0116571); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 3.28u 0.47s 00:00:03.75 Elapsed: 00:00:00.82
# Mc/sec: 1533.87
//
Query:       EEA21661.1  [L=1438]
Description: Exocyst complex component Sec3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   6.9e-220  732.1   5.5     9e-220  731.7   5.5    1.1  1  Sec3_C           Exocyst complex component Sec3
    7.8e-27   93.2   0.5    1.8e-26   92.1   0.5    1.6  1  Sec3-PIP2_bind   Exocyst complex component SEC3 N-terminal PI
     0.0065   16.8   0.7      0.026   14.8   0.1    2.4  2  Sec3_C_2         Sec3 exocyst complex subunit
  ------ inclusion threshold ------
       0.18   12.1   0.1          7    7.0   0.1    2.9  2  Antimicrobial_7  Scorpion antimicrobial peptide


Domain annotation for each model (and alignments):
>> Sec3_C  Exocyst complex component Sec3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  731.7   5.5    2e-223    9e-220       2     700 .]     698    1421 ..     696    1421 .. 0.97

  Alignments for each domain:
  == domain 1  score: 731.7 bits;  conditional E-value: 2e-223
      Sec3_C    2 dadeleerLsreLskleaan.ikrllesdkkveelkkdidkalkecdeldalltlysveLstlsedieyIEsqnngLQvksaNqklLykeLeellst 97  
                  +++ le +++re+ +++a++ + ++ +++ kv++l+k id +++ec+eld lltlys+eLstl++d++ IE+q++gLQv++aNqklL++eL++ll+t
  EEA21661.1  698 KIEDLESDIRREIGRVQATSwLGNIEQQEGKVDQLAKLIDRTIEECEELDGLLTLYSHELSTLHDDVAFIEAQSQGLQVQTANQKLLQSELQNLLKT 794 
                  699********************************************************************************************** PP

      Sec3_C   98 vslsesdleaLkeaelssanglealeealeaLfkAltaIdsdlk..................dlesdlgemravkerrerYekvsssFlrrlvefle 176 
                  +s+s++dl+ L+ea+l+  +g+ ++e+ l+ L+kA+ +Idsd +                    ++++g+mra++e+++ Y+++s  Fl+rl +f++
  EEA21661.1  795 LSISADDLRPLQEASLNGVDGVYQVETVLSMLYKAMLTIDSDIGqnkkrladaagdsssvgvYADTEIGQMRAIREKKDQYRAESGYFLQRLRQFMS 891 
                  *******************************************99**************************************************** PP

      Sec3_C  177 kkfksaekelgkdld..satkkklslekhlevlnlLliYsgLilflKevdaekfeallqqYnasiskvYereikeffeslkkslkkssgseesesls 271 
                   +fks +++  + ++   ++  k++   h+ ++++ ++Y  L+lf++ev+++++  l++ Y++++++ Y+ e++++f+++kk++kkssg+e se l+
  EEA21661.1  892 VAFKSSQQKRTNTSSnsLSDALKFDNTGHNAARQDIWMYYALMLFAREVSSSEWVGLINLYESDAKTPYQHELRDNFAAWKKAAKKSSGEE-SEILF 987 
                  ****9988877777744445556666779********************************************************999999.9**** PP

      Sec3_C  272 sssseekkteglalrksrkltlkssktganlsekaaqkktsgrlkpdeafaevLdeleplilveQnFiidfFhlssletldfnefvkqsapserrak 368 
                  +++++ek+  gl+  ++rklt++++kt++ ++ ++   ++ grl+  e+fa++L+e+ ++i  eQnFi++fFhl+sl t+df+++v++s+p err +
  EEA21661.1  988 THHEKEKEGDGLT-GAARKLTVRRGKTVRVQQGPKTIGEKPGRLDAFEVFAGALRETVKMIAEEQNFIVNFFHLNSLTTVDFPDLVAASNPGERRLP 1083
                  **98888888888.9*************7766555557889******************************************************** PP

      Sec3_C  369 dlsrsknvesdrelarkveklmeaifqflekelvnlvekvlkvdplqalgilvyleqkikeleesnqsflssvlqkllekvkslfkkfvdeqvesie 465 
                  d+s+++++++dr+la++ve+++++if+f++++++nlv++vl +d+lq++g+l+ le+ + e+ ++nq+f++++lqkll ++++lf++fvd+q++ ie
  EEA21661.1 1084 DFSTKQMHDPDRDLAKRVEQVVDGIFSFWANDMQNLVDWVLSIDQLQGIGVLAALEAAVSEFDDTNQDFIVHTLQKLLNRLNGLFNRFVDQQIRGIE 1180
                  ************************************************************************************************* PP

      Sec3_C  466 etkvkvkkrkgvlpfvrnfpefvkavEsmlssaera..lavrtlvdqaYeklieavfelLkreakeekaks.....vadeeedkeklnrhvllleNm 555 
                  etkvk++krkgv++f+r+fp+f++avE+m++ ++++  ++vr  v++aY+k+++a++e+Lk +ake +++      +  ++edke+ln+h+ll+eNm
  EEA21661.1 1181 ETKVKINKRKGVISFMRTFPHFSTAVENMFAAQSTSnfSDVRLAVNEAYNKINRAMWESLKFIAKEAPGQVsgattGVGDPEDKEALNYHILLIENM 1277
                  *********************************9999********************************99999995555***************** PP

      Sec3_C  556 nhfleeLselknsevleelrdeakqlfdeelelYvdavlrrplgkLieFvegveellqt.kkaaeissqaaySkqalkkilskYtakeirkgiekly 651 
                  nh++ee+++ +  +vle++rd+a q ++e+++lY+dav+rrplgkL++F+e++e+ll++ +++++i+s++++Sk+ +kk+ls++++ke r+g + l+
  EEA21661.1 1278 NHYFEEVDVRSL-PVLEKWRDRAIQDYHEHMKLYMDAVIRRPLGKLLDFIESTESLLTNsSNPTDIASRTSHSKSVAKKLLSSHDSKELRRGADLLK 1373
                  ************.************************************************************************************ PP

      Sec3_C  652 krvekhfledadravleeeLlqkvwseleeefiskylrlekiiqkvYdg 700 
                  krvekhf +dad+++l+++L+ kv +e+ +++ ++y+rl+ki+++vY+g
  EEA21661.1 1374 KRVEKHF-GDADDPGLSRSLVLKVFKECASRYEDVYDRLKKITDSVYEG 1421
                  *******.***************************************86 PP

>> Sec3-PIP2_bind  Exocyst complex component SEC3 N-terminal PIP2 binding PH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.1   0.5   3.9e-30   1.8e-26       1      90 []      88     187 ..      88     187 .. 0.97

  Alignments for each domain:
  == domain 1  score: 92.1 bits;  conditional E-value: 3.9e-30
  Sec3-PIP2_bind   1 kkkprfLclsvtksgrkevrlhkvKensngssfsigktWkLkeLklvegrdpdk.............ddpeFdltfdkpykweaesskeknaFir 82 
                     +kk r+++++ +ksgr  vr+hk++en++g+ fsigktW+L++L+ ++ +++ +             ++  F++t++k+y+w+a++ ke+++Fi+
      EEA21661.1  88 NKKLRLIIVALRKSGR--VRMHKARENNDGT-FSIGKTWMLDDLNSIQCYSDLPattqveqqqkqwaSNVGFTVTIGKQYYWQASNYKERDFFIA 179
                     6999**********99..************9.********************999************7777************************ PP

  Sec3-PIP2_bind  83 sLvklykk 90 
                     sLvk+ykk
      EEA21661.1 180 SLVKIYKK 187
                     ******97 PP

>> Sec3_C_2  Sec3 exocyst complex subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.1   5.9e-06     0.026      32      85 ..     717     770 ..     682     771 .. 0.75
   2 ?   -2.4   0.1       1.4   6.1e+03       5      37 ..    1143    1175 ..    1141    1187 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 5.9e-06
    Sec3_C_2  32 esveelaeekielkevkdilqdsilGCeslfstlnlyslelstvlndvinieqq 85 
                 + + ++ +++ ++ ++ + ++ +i  Ce l   l lys elst  +dv  ie q
  EEA21661.1 717 SWLGNIEQQEGKVDQLAKLIDRTIEECEELDGLLTLYSHELSTLHDDVAFIEAQ 770
                 4456778888999999999999*****************************998 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 1.4
    Sec3_C_2    5 seldWseedaikdvlkelefsldeaiiesveel 37  
                  se+d +++d i + l++l++ l++ +   v++ 
  EEA21661.1 1143 SEFDDTNQDFIVHTLQKLLNRLNGLFNRFVDQQ 1175
                  667778889999999999999999877777665 PP

>> Antimicrobial_7  Scorpion antimicrobial peptide
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0     0.092   4.1e+02       1      18 [.    1320    1337 ..    1320    1344 .. 0.89
   2 ?    7.0   0.1    0.0016         7       8      25 ..    1350    1367 ..    1348    1371 .. 0.92

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.092
  Antimicrobial_7    1 GKvwDwIKstAkkvwnSe 18  
                       GK +D I st + + nS 
       EEA21661.1 1320 GKLLDFIESTESLLTNSS 1337
                       9*********99999986 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0016
  Antimicrobial_7    8 KstAkkvwnSepvkqLKn 25  
                       Ks+Akk+++S   k+L++
       EEA21661.1 1350 KSVAKKLLSSHDSKELRR 1367
                       9***************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1438 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       711  (0.0396564); expected 358.6 (0.02)
Passed bias filter:                      459  (0.025601); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.91u 0.32s 00:00:01.23 Elapsed: 00:00:00.49
# Mc/sec: 8875.14
//
Query:       EEA21662.1  [L=2132]
Description: dedicator of cytokinesis domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
     2e-111  372.6   0.0   3.6e-111  371.7   0.0    1.5  1  DOCK_N      DOCK N-terminus
    1.3e-42  146.1   4.7    2.5e-42  145.2   4.7    1.4  1  DHR-2       Dock homology region 2
    2.6e-38  131.8   0.0      5e-38  130.9   0.0    1.5  1  DOCK-C2     C2 domain in Dock180 and Zizimin proteins
    5.1e-05   23.1   0.0    0.00047   20.0   0.0    2.3  2  SH3_9       Variant SH3 domain
    0.00013   21.5   0.0    0.00026   20.5   0.0    1.5  1  SH3_1       SH3 domain
  ------ inclusion threshold ------
      0.087   12.7   0.0        6.4    6.7   0.0    2.6  2  Phage_AlpA  Prophage CP4-57 regulatory protein (AlpA)


Domain annotation for each model (and alignments):
>> DOCK_N  DOCK N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  371.7   0.0  1.2e-114  3.6e-111       1     377 []     169     583 ..     169     583 .. 0.95

  Alignments for each domain:
  == domain 1  score: 371.7 bits;  conditional E-value: 1.2e-114
      DOCK_N   1 pslkigdetvvsaeeplvdEiascLREWhsl.lkelllkrkyelfdklsklieeLdlaRrqlLsgvltadelkelrektvwrLvrgNkllglDviVRdp 98 
                 p+lkigdet++s eeplvdEias LREWhs+ l+elll+r+y +++++ +++ +LdlaRrqlL++vlt++e +++r++tvw+LvrgNk+l ++viVRdp
  EEA21662.1 169 PMLKIGDETPTSYEEPLVDEIASSLREWHSTnLHELLLTRQYGSVETMYNVVLDLDLARRQLLHDVLTSKEKSAVRQTTVWNLVRGNKMLTGEVIVRDP 267
                 8************************************************************************************************** PP

      DOCK_N  99 egrgrvdtdedSvvelyklqsemalldespkikeeksrsekseseaaslhhllldlksfvgaslgeeaelffsLydkke...skflsEnflvrlnksgl 194
                 +++gr++t++dS++el+klqsem++ d++p+++           +a++l hlll+lk ++g++ g +++l ++L++k++    k+lsE+++++++++++
  EEA21662.1 268 KENGRLLTGDDSAIELTKLQSEMSMFDSDPRHQG----------DASTLRHLLLELKTIAGSHAG-PVTLSLYLSTKADsdaLKPLSETYVLEIQSADS 355
                 **********************************..........9****************9999.*************88889*************** PP

      DOCK_N 195 pkelaksleklrtLFtDLsskDlgd...areklyLVvkivrngrv....................................smelkskkkrsassrses 254
                 +  la+s +kl+tLFt+L ++D+gd    +  lyLVv + + +                                      sm ++ k+ r+++ ++  
  EEA21662.1 356 FMALANS-SKLKTLFTELCAADVGDgagGEAHLYLVVIVQSAELPrpslpyaartsssrdggmnrnpsnmhsvkgsvkgrrSMVWTAKSPRPGQPETIR 453
                 ******6.5******************99********99888666*****************************************9999999888554 PP

      DOCK_N 255 askkseekeessetsesssakkektvrRpfGvavldlsdlkglkqsdeekehvlkiyvp.........enesdfdqlhediiksrtkkyekspraeglq 344
                 ++  +++++ +s+ + ++++ k+ tv R++G ++ld+ ++  ++q ++e ehv++i++p         ++ + fd+l++ ++ s++++y k  +a++l+
  EEA21662.1 454 ETPPRSSDSANSQGQGENATLKDATVIRTVGAGILDVAHI--VRQ-NSEAEHVINIWSPlgedveeggNDLEGFDELIRIVLPSSSGRYFKCYQASQLH 549
                 4443555555666668888889999***************..889.*********************9999**************************** PP

      DOCK_N 345 VsLklf.hgdleqlrkenptllrgvaltrKlGFp 377
                 ++  +f  +d+++l+++nptl+++v++tr++GF+
  EEA21662.1 550 LHFYPFiDSDADALVRNNPTLMHNVTQTRRMGFA 583
                 *********************************5 PP

>> DHR-2  Dock homology region 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.2   4.7   8.4e-46   2.5e-42       4     434 ..    1323    1710 ..    1320    1813 .. 0.81

  Alignments for each domain:
  == domain 1  score: 145.2 bits;  conditional E-value: 8.4e-46
       DHR-2    4 felekkknfarvklqviialsklvsee..del..neerlkeslktinsyaksdkelkessfpeqvkellkrlrtvlkatvkmkeekedpemladlqy 96  
                  ++l++  +++ ++++++++l+ l  ++  +e   ++ ++ e l+ ++++ +sd++     ++++ k l   + ++l+ +v  +      e+l+ l  
  EEA21662.1 1323 WDLTQ--DLSIIEMEIVTSLDVLFQTKhmNESitQKLFITELLDLFEKIQDSDEA-----LATDAKGLIGTIDELLELLVACN-SGGITESLHALR- 1410
                  56664..78889999*********9994322234777777778888777776664.....55556777777777777767766.334446677776. PP

       DHR-2   97 slansyk..sspdlritwLeslaekhaenenfsEaaqclihaaaLiaeylkllkkipkklgasaFekispnvlkeesesasalkedsgvcdseefte 191 
                   l++++k  + +d+ i+++++la+ +a+++n++ aa +l ++a+L+    +++              +  n + ++++sa+++ke            
  EEA21662.1 1411 -LMEFMKdmDREDIFIRYVHELAQTQATEHNYTQAALALQFHADLYTWEPTRM------------VPALTNPA-YPEQSAFDRKE------------ 1481
                  .5688886456************************************333333............23344554.66678888898............ PP

       DHR-2  192 eglvellekaiellkkgelyElaielyklliplyekk.rdykklseihkklaelyekivetsksekRlfgtYyRVgFyGkkF.eeldgkeyvYkepk 286 
                       l+ k+i+ +++g+ +  a   yk+li +ye+  +d++kls++  ++a++ye+i +    e++ f++Y+RV++ G +F  +l++k++++    
  EEA21662.1 1482 ----ALYFKIIQHFEDGKAWTHALACYKELIEQYEHIvMDFTKLSRAQGSIAKIYESISK----EDKAFPRYFRVSYRGLGFsATLRDKQFIFEALP 1570
                  ....79******************************99**********************....99******************************* PP

       DHR-2  287 ltrLseiserlksqysekfgeekveiikdskpvdkseldpdkaYiqitaVePyfeeeelkerktsFernnnvnrFvfetP..Ftksgkkaqg..sle 379 
                   +r++++++r+++ ++ +  +       +s+++  +  d + +++qi aV P  e     ++ ++   +   +  + + P  F +++k++ +  +++
  EEA21662.1 1571 NERMASFTDRMQKLHPAAQIT-------SSHEI--E--DIEGQFLQISAVSPHREVMHPVYQRSKVP-HSVREHLLISVPlqFSHTSKRHTSglNVK 1655
                  ***************999874.......78876..5..5559**********776555545555554.344455567888888877633333588** PP

       DHR-2  380 eqwkrrtiLttensfPylkkRlevvskeeielsPievaieeiekkteeleaaika 434 
                  eqw ++ti+tt++ fP++++R+e+v + ++el+P++ aie   +kt+el+ + ++
  EEA21662.1 1656 EQWVEKTIFTTAEPFPNILRRSEIVATDVVELTPLQTAIERTWRKTQELHLLEQH 1710
                  *************************************************987776 PP

>> DOCK-C2  C2 domain in Dock180 and Zizimin proteins
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  130.9   0.0   1.7e-41     5e-38       1     194 [.     586     780 ..     586     781 .. 0.87

  Alignments for each domain:
  == domain 1  score: 130.9 bits;  conditional E-value: 1.7e-41
     DOCK-C2   1 pgdvrNdlYvtlksgefss.........kgskssa.........kniqvtvevrdsdgerlekaiylgsgeelvsefrsvvlyhnkqptfneeiKialp 81 
                 p ++r+d+Y+t+ +++f+                +         +n+q+t+evr+ +g rle++i+++s+++ ++ +r++v+ +n++  +n++i++++p
  EEA21662.1 586 PSQPRSDIYLTISRAKFPWpallchpqtG-----QvpvpvhtgfRNLQLTLEVRNGSGARLERCIFASSNSTGHTAWRTTVTDRNSS--WNQTIRLNIP 677
                 6789*************779997655540.....1455566666**********************99****************999..********** PP

     DOCK-C2  82 ieltekhHLlFtfrhvsceekkkekdkeeeekpfgyaflpLlkedgraflkdgehelpvy...k....k.elppsgYlslpssrtssseeqkgpsekwl 172
                 +e+++++H+++++++ +             e pf++++lpL++  ++af++dg h+l+++   k      e+  ++Ylslp+s+ +++++   p+e+ +
  EEA21662.1 678 TEQVPGAHVIMSIADAP-------------EFPFALCWLPLWN--QQAFIHDGPHSLLLHaydKvtssVdEEGRGAYLSLPWSSLHKNSSI--PDES-V 758
                 ****************9.............49**********7..899************665366552244449********87777777..6666.9 PP

     DOCK-C2 173 dnskdtfkvrtklcSTiltqde 194
                 +++ +t++v+t+lcST ++qd+
  EEA21662.1 759 TGPLSTVHVETNLCSTEYSQDQ 780
                 9********************7 PP

>> SH3_9  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   0.0   1.6e-07   0.00047       1      35 [.      14      50 ..      14      61 .. 0.93
   2 ?   -0.2   0.0       0.3     9e+02      40      49 .]      75      84 ..      72      84 .. 0.92

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 1.6e-07
       SH3_9  1 AlypyepreddeLsLqrGDvitviee..sedgWlegs 35
                A+yp++p +++ L+L+ GD +++ie+  +++ W++g 
  EEA21662.1 14 AIYPFQPSSPADLPLELGDELYIIEQggANGSWFRGY 50
                89**********************88789******96 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.3
       SH3_9 40 tGlvPanyve 49
                +G +P+n+ve
  EEA21662.1 75 SGIFPRNCVE 84
                599******7 PP

>> SH3_1  SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5   0.0   8.6e-08   0.00026       1      35 [.      13      49 ..      13      52 .. 0.92

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 8.6e-08
                EESSSBEXSSTTBXEBSTTEEEEEEEECSS..SEEEE CS
       SH3_1  1 iAlYDYeaeesdELsfkkGDviivleksed..gWwkg 35
                +A+Y+++++++ +L+++ GD++ ++e+  +   W++g
  EEA21662.1 13 VAIYPFQPSSPADLPLELGDELYIIEQGGAngSWFRG 49
                7*************************98888889887 PP

>> Phage_AlpA  Prophage CP4-57 regulatory protein (AlpA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0     0.029        86      17      32 ..     590     605 ..     584     614 .. 0.88
   2 ?    6.7   0.0    0.0021       6.4       9      42 ..    1515    1555 ..    1512    1558 .. 0.78

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.029
  Phage_AlpA  17 rstiYrlikdgeFPkk 32 
                 rs iY  i++++FP +
  EEA21662.1 590 RSDIYLTISRAKFPWP 605
                 9*************76 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0021
  Phage_AlpA    9 Veqktglsrst.....iYrlik..dgeFPkkvkLGvrsVgW 42  
                  V+ +t lsr++     iY+ i+  d+ FP+ ++ + r  g+
  EEA21662.1 1515 VMDFTKLSRAQgsiakIYESISkeDKAFPRYFRVSYRGLGF 1555
                  6777777776444444*****97788********9998888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2132 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       865  (0.0482459); expected 358.6 (0.02)
Passed bias filter:                      521  (0.0290591); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.19u 0.36s 00:00:01.54 Elapsed: 00:00:00.54
# Mc/sec: 11886.01
//
Query:       EEA21663.1  [L=311]
Description: Ser/Thr protein phosphatase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.5e-11   43.3   0.2    8.1e-11   42.8   0.2    1.3  1  Metallophos    Calcineurin-like phosphoesterase
    1.1e-07   32.2   2.4    4.5e-06   27.0   2.3    2.2  1  Metallophos_2  Calcineurin-like phosphoesterase superfamily d
  ------ inclusion threshold ------
      0.047   13.7   0.0      0.073   13.1   0.0    1.2  1  R2K_3          ATP-grasp domain, R2K clade family 3


Domain annotation for each model (and alignments):
>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.8   0.2   1.4e-14   8.1e-11       2     203 ..      11     234 ..      10     235 .. 0.61

  Alignments for each domain:
  == domain 1  score: 42.8 bits;  conditional E-value: 1.4e-14
                  EEEEEESBTBTTCCTHHHHHHHHHHHH..HHHTTESEEEEESTSSSSS.....HHHHHHHHH.HHHHHHHTSEEEEEC-TTS................ CS
  Metallophos   2 rilvigDlHlalgggqlddllkllddl..lreekpdlvllaGDlvdrg.....dlekellel.laalvkypipvylllGNHe................ 75 
                  ri +i+D+H      q + +   +++   ++ +k d++l+aGDl+  g     ++  ++l+  ++a +k     ++++GNH+                
   EEA21663.1  11 RICIISDTH-----TQTPHTSSSIHKPyrHPLPKSDIFLHAGDLTTIGrqaehEVIVDMLKHdVDAEIK-----IVIAGNHDlthdrkfyaergvrrh 98 
                  899******.....777777777744444445899********99999765443333333333444444.....********9888866666655555 PP

                  ........CHHHHHHHHHHHHHHHHHHHEHHHCEEETSEEEEEETTEEEEEEEESE..CEEE.THHHHHHHHHHHSCHHHHCC....HHHHHHHHHHT CS
  Metallophos  76 ........gfeeellnkygylgifsepwrsdaevfnnlplaslgsgslkvlllhGg..spel.lvsldklgslnleleapepg....dewlkdlekre 158
                               +  +y+++    +++ +  e +  + l s  +g    +++++   +pe+  + +   + ++++ ++p p     +e+  d     
   EEA21663.1  99 gsgrledvD---AIRALYTDESAKEAGIVYMEEEVRTFTLKS--NG--AKFTVYASpyTPEFcGWAFAYERDEDRFNPNPAPIassvNEFVPD----- 184
                  554432221...333333333333333333344445555555..22..234444445677778555555555555555555556678******..... PP

                  TCSEEEEEESSESS..CSSSCSCCHHHHH...HHHHHTTESEEEEESSSS CS
  Metallophos 159 kadwvivlgHsply..rgsgylfgdeale...dllkkygvdlvisGHtHv 203
                     ++i l+H p+     + y+  +  ++   + +++ ++ l ++GH+H+
   EEA21663.1 185 FPGVDIMLTHGPPAgiLDKIYWGKNVGCDnllKACRRARPRLHVFGHIHE 234
                  99************9833444444444442335667777**********7 PP

>> Metallophos_2  Calcineurin-like phosphoesterase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.0   2.3   7.5e-10   4.5e-06       2     131 ..      11     236 ..      11     259 .. 0.75

  Alignments for each domain:
  == domain 1  score: 27.0 bits;  conditional E-value: 7.5e-10
  Metallophos_2   2 klaiiSDlH.....snldaleavlealkevgvdaiihaGDl....eeeepevleellela....pvlaVrGNnD...................... 62 
                    +++iiSD+H      + ++++   + l +   d  +haGDl     ++e ev+ ++l+        +++ GN+D                      
     EEA21663.1  11 RICIISDTHtqtphTSSSIHKPYRHPLPKS--DIFLHAGDLttigRQAEHEVIVDMLKHDvdaeIKIVIAGNHDlthdrkfyaergvrrhgsgrle 104
                    699******666654444555555556666..********877455555566666666557884446789************************** PP

  Metallophos_2  63 .......................................................eev.veedvlreaaelgtdlpeeaelelagekvlliHgdpl 102
                                                                             +  e+++  ++a+++ ++ +e + +++g+++ l+Hg p 
     EEA21663.1 105 dvdairalytdesakeagivymeeevrtftlksngakftvyaspytpefcgwafaY-ErDEDRFNPNPAPIASSV-NEFVPDFPGVDIMLTHGPPA 198
                    **********9999999999998888777777777777777777776666665532.234556666666666666.7777778**********988 PP

  Metallophos_2 103 ........gvkdalaellke.aeegsdvvvcGHtHvpe 131
                            g + + ++llk+   ++ ++ v+GH+H+++
     EEA21663.1 199 gildkiywGKNVGCDNLLKAcRRARPRLHVFGHIHEAY 236
                    ******995555555555551114556********984 PP

>> R2K_3  ATP-grasp domain, R2K clade family 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   1.2e-05     0.073      52     171 ..      63     193 ..      43     195 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.2e-05
       R2K_3  52 hflgrdvrqlsrlvel...eaeeepvFvkprgdk.lfggvVlrefeelralaakledtevlvsevvrfsaEwRvFvv..dG..evvaasrYr....... 135
                 ++l++dv++ +++v     + +  + F  +rg + + +g    ++e++ a++a+ +d++   + +v + +E+R+F +  +G    v as+Y        
  EEA21663.1  63 DMLKHDVDAEIKIVIAgnhDLTHDRKFYAERGVRrHGSG----RLEDVDAIRALYTDESAKEAGIVYMEEEVRTFTLksNGakFTVYASPYTpefcgwa 157
                 777877777777776666444455557776776633333....56777777788888888888999**********96633436788899989999887 PP

       R2K_3 136 .kanddpdl.epdlaafaeavralvgappfyvlDvavt 171
                    + d d  +p +a +a+ v+++v  p f  +D+ +t
  EEA21663.1 158 fAYERDEDRfNPNPAPIASSVNEFV--PDFPGVDIMLT 193
                 633333333799*************..99999999665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (311 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       459  (0.025601); expected 358.6 (0.02)
Passed bias filter:                      424  (0.0236488); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 2049.45
//
Query:       EEA21664.1  [L=200]
Description: 40S ribosomal protein S8e [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.1e-53  180.2   0.8    2.3e-53  180.0   0.8    1.0  1  Ribosomal_S8e  Ribosomal protein S8e


Domain annotation for each model (and alignments):
>> Ribosomal_S8e  Ribosomal protein S8e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  180.0   0.8   1.3e-57   2.3e-53       1     137 []       1     186 [.       1     186 [. 1.00

  Alignments for each domain:
  == domain 1  score: 180.0 bits;  conditional E-value: 1.3e-57
                    XXXBXXCCCSEESSTEEXXXSSXXXCCSBXXXXXXXEESSHEEEEEEETTCEEEEEEESESEEEEEETTTTEEEEEEEEEEECSSSTCHHHHTTC- CS
  Ribosomal_S8e   1 mgisrdskhkrkltGgkakllrkkrkielgrkekatklgaervkvvrvrgGkrkkralrlkkanvthpeekvtkklkIlgVkknpsnneyvrlgvl 96 
                    mgisrds+hkr++tG+k++ +rkkr++e+gr++++t++g +rv+ vr+rgG++k+r+lrl+++n+++++e++++k++++ V  +psnne+vr+++l
     EEA21664.1   1 MGISRDSRHKRSATGAKRATYRKKRAFEKGRQPANTRIGPKRVHLVRTRGGNTKYRGLRLDSGNFSWGSEGISRKVRVIVVAFHPSNNELVRTNTL 96 
                    99********************************************************************************************** PP

                    -TTEEEEEESHH.................................................HHHHHHTTEEEEEEESEHHHHSSEEEEEE CS
  Ribosomal_S8e  97 tKgaiievdvse.................................................LgevtqsgkvvAqvtsrPgqdGcvnavlL 137
                    t++a+++vd+++                                                 L+ ++++g+++A+++srPgq+G+v++++L
     EEA21664.1  97 TRSAVVQVDAAPfrqwyeahygqpigrrrqqksevaeekksksveskqaarfaasgkvenaLERQFEAGRLYAVISSRPGQSGRVDGYIL 186
                    *****************************************************************************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (200 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       797  (0.0444531); expected 358.6 (0.02)
Passed bias filter:                      446  (0.0248759); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.25s 00:00:00.68 Elapsed: 00:00:00.40
# Mc/sec: 1498.78
//
Query:       EEA21665.1  [L=252]
Description: integral membrane protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-19   70.6   0.1    1.9e-19   70.1   0.1    1.3  1  DUF2470   Protein of unknown function (DUF2470)


Domain annotation for each model (and alignments):
>> DUF2470  Protein of unknown function (DUF2470)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.1   0.1   1.1e-23   1.9e-19       1      77 []      27     109 ..      27     109 .. 0.89

  Alignments for each domain:
  == domain 1  score: 70.1 bits;  conditional E-value: 1.1e-23
                 HHHHHHHHHHH-HHHHHHHHHHCST-TTC..CEEEEEEE-SSEEEEEE...C......CEEEEEE-SS---SCCHHHHHHHHH CS
     DUF2470   1 sariiaHMNkDHaddlllylrhygkvkea..ksarmtdidldgltlrl...gakags.ektvripFdpplkswaearerLveM 77 
                 ++ri++HMN+DH+d+l+ +l  y+kv+ +  ++a++++i l g+t+++    ++a+s ++   +pF+p l++++ear+++veM
  EEA21665.1  27 KQRIVSHMNSDHRDSLSMFLVIYNKVPYTqaQTAQIEEIRLSGMTISTadyPDRAKSsRTNFFVPFEPALNGYEEARHKVVEM 109
                 79**********************66655326669*************998555556799**********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (252 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       707  (0.0394333); expected 358.6 (0.02)
Passed bias filter:                      526  (0.0293379); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.25s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 1796.42
//
Query:       EEA21666.1  [L=1104]
Description: plasma membrane phosphate transporter Pho87, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.7e-36  126.3   0.7    4.5e-23   82.8   0.0    2.5  3  SPX              SPX domain
    5.2e-27   95.0  45.4    8.1e-27   94.4  45.4    1.2  1  Na_sulph_symp    Sodium:sulfate symporter transmembrane regio
    6.4e-24   84.7  40.6    1.6e-23   83.3  40.6    1.8  1  CitMHS           Citrate transporter
  ------ inclusion threshold ------
      0.016   14.8   0.3      0.062   12.9   0.3    2.0  1  Cytochrome-c551  Photosystem P840 reaction-centre cytochrome 
       0.92    9.9   4.6        7.7    7.0   5.7    1.9  2  PBP1_TM          Transmembrane domain of transglycosylase PBP


Domain annotation for each model (and alignments):
>> SPX  SPX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.7       1.7   6.2e+03      53     121 ..     130     207 ..      97     222 .. 0.43
   2 !   42.1   0.0   2.9e-14     1e-10       1      37 [.     243     279 ..     243     293 .. 0.88
   3 !   82.8   0.0   1.3e-26   4.5e-23     175     382 ..     289     519 ..     277     520 .. 0.66

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 1.7
         SPX  53 pedskkksse.......rtepstsaaadesgnsaadasssepkdeae.......................slprrsplsrssrssssygglvssppsan 121
                 p++s++ +++       r                      +p ++ +                       s ++ +++ +  +++ +y + v++p + n
  EEA21666.1 130 PSSSSTRDTQiarplteR---------------------VTPHTTSTtqgctaaglnsgfvshddtasilSGSQDHEGTGLLQTQPEYLNRVQQPQNIN 207
                 333333333322222211.....................111111112333333333333322222233322333333334444444444444444444 PP

  == domain 2  score: 42.1 bits;  conditional E-value: 2.9e-14
         SPX   1 MKFakeLeenlvpEWrdaYldYkqLKKlIkkvqrele 37 
                 MKF+++L++n vp W  +Y+ Y+ LKKlI+ ++++ +
  EEA21666.1 243 MKFSHSLQFNSVPDWSTHYIAYDNLKKLIYNLEKQVH 279
                 ********************************99655 PP

  == domain 3  score: 82.8 bits;  conditional E-value: 1.3e-26
         SPX 175 yetrplr.....aekeFferLdseLnkvetFykakeeefterlesLrkqlealrprrikeaeerksdlyrwre..................ifglksve 250
                 +e++pl       ++ F + Ld+e +k+ +Fy+ ke   + ++e+  k+l++ +++   +  e  ++  ++ +                    gl++ e
  EEA21666.1 289 SESSPLLdtsvdTDTIFRRALDAEMEKICSFYRIKELTIFGEVEDVLKELAQYKASTDGLGMEPVTEAVTK-SrtlsigsrprtgsilhslGLGLNRRE 386
                 3333333344559****************************************775555444443332222.224556666777788776644444444 PP

         SPX 251 aqvfessreldrgelse..eardkevseelekngwikptksklekkrneralekvkpektlkafldsvrrdylrkenrvklkkakkklkkafvelYrgL 347
                 + +++s  + +  ++++  +++ ++  ee+ + g++++ ++ ++  r+    +++ +++ ++  ++ +++++  + +   l +a   lkk+++  Y++L
  EEA21666.1 387 STISDSIGDEEDDDEDDhdSDDPESPVEESRRPGSRRRSRDVAGGDRSDGYPSDMGDSRLWNLGNSRHEEEQHDQ-HVLDLYNAGVALKKRVISVYVSL 484
                 444444444333332223233444444444444444444444444443333444413555555555555555555.9999999**************** PP

         SPX 348 elLKsYqeLNrtAFrKIlKKfDKvtaltaskrymk 382
                 ++LKsY+ LN+t+F+K lKK+DK++ +++++ y++
  EEA21666.1 485 CELKSYILLNKTGFSKALKKYDKILDRNLRRAYIN 519
                 *******************************9986 PP

>> Na_sulph_symp  Sodium:sulfate symporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.4  45.4   2.3e-30   8.1e-27       7     463 ..     644    1096 ..     638    1102 .. 0.83

  Alignments for each domain:
  == domain 1  score: 94.4 bits;  conditional E-value: 2.3e-30
  Na_sulph_symp    7 lllllvvlliilllPapdgleskawrllaifiaaivglileplplavialialsllavligvla..........akalsevlsgfssdttlLvf 90  
                     l+ ++++++  +ll +p+  +++++ +la+++++ + + +e +pl v++l++  l+++l  + +            a+++v +    ++++L++
     EEA21666.1  644 LVGIMIIFA--VLLSVPIMEKPEQQNCLAMLVFVSLLWATEVIPLFVTSLLIPFLVVILRVMRSeekpharlapDAATKAVFASMWTSVIMLLL 735 
                     344444444..4667777789999*************************998888877777777889*****999999**************** PP

  Na_sulph_symp   91 aalliaaavektgLgkRiAlvlvkivGkrtliLgy..alvladlllapatpsntAraggivfpvikslssafgsepekqserkigaylmltvvq 182 
                     ++++iaaa+ k  + +R+A ++++  G++++i+ +  + v ++l++++++ ++     +i+ p +++l++      e++     ++ l+l ++ 
     EEA21666.1  736 GGFTIAAALSKYDIARRMATFVLSRAGTSPRIVLItnMFVSMFLSMWISNVAAPVLCYSIIQPLLRNLPP------ESN----FSKALILGIAL 819 
                     ******************************7776622566678999999999999999999999999986......333....34479999*** PP

  Na_sulph_symp  183 sasitsiaflTamApNllllglinsilgveitwasWflaaiptgvillllvplllyvlyppeikkkeeakavaktelkelGpltarekallilf 276 
                     +a ++++a   a  +N+++l+ +       i+w+ Wf + ip+ ++++l ++++l v + p    +    + +k+       +t  ++ + +  
     EEA21666.1  820 AANVGGAASPIASPQNIIALENMY----PAISWGTWFFISIPVCILCILAIWIILLVTFNPGRGTTIVPIRPVKD------SFTGTQWFVTLTT 903 
                     *********************999....78*************************99999987666344444444......68899******** PP

  Na_sulph_symp  277 vlllllWifgesln...idattvaivvlvillllrvldWkDivkqktaWntllllgglialakllersgliewlgnklttslsglspavaiiii 367 
                     ++ ++lW f+++l+    d +++ai+ +v+ + + +l+ +D   ++  W +++l +g+++l k  + sgl++ ++ ++t  ++ +s    ++ +
     EEA21666.1  904 LITIVLWCFSHQLDtvfGDMGVIAIIPMVLFFGSGILTKEDF--NNFLWTIIILAAGGLVLGKAVTSSGLLHTIAGAITERVAHFS-LYGVLLV 994 
                     ***********999876699********************76..7799***********************************665.4566677 PP

  Na_sulph_symp  368 lslfvlvhylfaSatAttaallpillavaqaipg.appllvalllalatslagfllpyatgpnpivf.......gagylkvkdywrlGfilsii 453 
                     +s ++lv   f S t    ++lp++  v+ ++   + p l++++ al  s+a + lp ++ pn+ +        g  yl v ++   G++ s++
     EEA21666.1  995 FSSLILVMATFISHTVAALIVLPLVQQVGVGMENpH-PNLLVMTSALMCSVA-MGLPTSGFPNMTAImmeipgtGQRYLRVSHFLTRGVPGSLV 1086
                     788899999999*99999*************97744.455555555555555.5566666665533212333225569**************** PP

  Na_sulph_symp  454 gllillllga 463 
                     +++i++++g 
     EEA21666.1 1087 SFVIVVTVGY 1096
                     ******9995 PP

>> CitMHS  Citrate transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.3  40.6   4.6e-27   1.6e-23       2     298 ..     677    1037 ..     676    1100 .. 0.79

  Alignments for each domain:
  == domain 1  score: 83.3 bits;  conditional E-value: 4.6e-27
                  xxxxxxxxxxxxxxxxxxxxx....xxxxxx..............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxx RF
      CitMHS    2 vllileklrldvvallvlvll....vltiee..............alsgiaspiillllgamiigaaleetGlfdrlaakllrlaggkrd.llvllv 79  
                  +l+++e+++l v++ll+  l+    v+  ee              +++ +  ++i+lllg+++i+aal++  +++r+a+++l++ag++++ +l+  +
  EEA21666.1  677 LLWATEVIPLFVTSLLIPFLVvilrVMRSEEkpharlapdaatkaVFASMWTSVIMLLLGGFTIAAALSKYDIARRMATFVLSRAGTSPRiVLITNM 773 
                  6999***********9998889777444444777777777776656666666678***********************************88888** PP

                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................. RF
      CitMHS   80 lltallsafvsndgvvlimipivlslakrlkklppl......lliplalaaniggaltpiGtpttraaarpglslpnlll................. 153 
                  +++++ls+++sn+++ +++ +i+ +l +    lpp       l++ +alaan+gga++pi  p            +n+++                 
  EEA21666.1  774 FVSMFLSMWISNVAAPVLCYSIIQPLLRN---LPPEsnfskaLILGIALAANVGGAASPIASP------------QNIIAlenmypaiswgtwffis 855 
                  ***************77777777777765...344344455599*******************............6666666666666666666666 PP

                  xxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxx....................................xxx RF
      CitMHS  154 lalllvgllplvllfmfgvalalpvnap....kvkkqkaiieaiarsllpvatillla....................................ykk 210 
                  +++++ ++l++++++++++        +      +  k+ +   ++++ +  t+++++                                    +++
  EEA21666.1  856 IPVCILCILAIWIILLVTFNPGR----GttivPIRPVKDSFTGTQWFV-TLTTLITIVlwcfshqldtvfgdmgviaiipmvlffgsgiltkedFNN 947 
                  55555556666666533332222....133333333333333333322.233333333447888888888888888888999999************ PP

                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...x.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      CitMHS  211 veWsvlllfaGvfllvgaleqtGilealadllga...g.gplvalalvlgliallsafisnvavaalmapialgmapalgllspsplalala 298 
                    W +++l+aG ++l++a++ +G+l+++a+++++      ++ +l+++ +li ++  fis + +a++++p++ ++  +++  +p+p +l+++
  EEA21666.1  948 FLWTIIILAAGGLVLGKAVTSSGLLHTIAGAITErvaHfSLYGVLLVFSSLILVMATFISHTVAALIVLPLVQQVGVGME--NPHPNLLVMT 1037
                  ********************************5568635777777788889999*******************9888655..6777777666 PP

>> Cytochrome-c551  Photosystem P840 reaction-centre cytochrome c-551
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.3   1.7e-05     0.062      64     109 ..     836     882 ..     807     898 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.7e-05
                      XXXXXXXXXXXX.XXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Cytochrome-c551  64 ilglGklsskis.dkw.flsfplsilvivavmfvslevvwekGrtttv 109
                      i++l ++  +is   w f+s+p++il+i+a+ ++ l v ++ Gr tt+
       EEA21666.1 836 IIALENMYPAISwGTWfFISIPVCILCILAIWIILL-VTFNPGRGTTI 882
                      6778888888884356369**********9987777.*********97 PP

>> PBP1_TM  Transmembrane domain of transglycosylase PBP1 at N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   5.7    0.0021       7.7      28      70 ..     386     424 ..     380     429 .. 0.52
   2 ?   -2.2   0.0       1.6   5.8e+03      58      85 .]     619     654 ..     602     654 .. 0.60

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0021
     PBP1_TM  28 rrrrdddyddeyddeedDdddddeeeevprkgkkkkpprkkrr 70 
                 ++   d + de dd+edD+d dd e++v       + p ++rr
  EEA21666.1 386 ESTISDSIGDEEDDDEDDHDSDDPESPVEES----RRPGSRRR 424
                 2223555556666666666666666666444....33444443 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.6
     PBP1_TM  58 kgkkkkpprkkrr........wlwlliklflvlvvl 85 
                 +gk+ k+p  ++          +  l+ ++++++vl
  EEA21666.1 619 RGKEIKTPLGRWYfpewvcslSFFSLVGIMIIFAVL 654
                 566666666666544444432355688888888886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1104 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       800  (0.0446204); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.80u 0.31s 00:00:01.11 Elapsed: 00:00:00.47
# Mc/sec: 7135.45
//
Query:       EEA21667.1  [L=364]
Description: 30S ribosomal protein S7, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.3e-30  105.2   0.0    4.4e-30  104.3   0.0    1.4  1  Ribosomal_S7  Ribosomal protein S7p/S5e


Domain annotation for each model (and alignments):
>> Ribosomal_S7  Ribosomal protein S7p/S5e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.3   0.0   2.5e-34   4.4e-30      18     148 ..     199     351 ..     188     352 .. 0.90

  Alignments for each domain:
  == domain 1  score: 104.3 bits;  conditional E-value: 2.5e-34
                   TTSBHHHHHHHHHSBTTBHHHHHHHHHHHHHHHHHH.................HSS...-HHHHHHHHHHHCS-SEEEEEEB...SSSSBEEEEEEE CS
  Ribosomal_S7  18 ynselveklinklmkdGkkslAekivygaldiieek.................tkk...dplevleeAlenvkPrvevksrr...vGGatyqvpvev 91 
                     +++ve++++ lm+dGk s+A+k ++ +ld ++++                   +   +p+ +l+  +++v+P +++++ +    GGa++++pv++
    EEA21667.1 199 RYDPVVEQFTKLLMEDGKLSRAQKDMEFILDTLRTSappkidprrrlltslpsP-QlplNPVIYLNLLVDSVAPLIKIRQQKglaGGGASVPMPVPL 294
                   4579*******************************9888888888887766641.255599*******************9988889********** PP

                   -HHHHHHHHHHHHHHHHSTSSSS-HHHHHHHHHHHHHTT-SHHHHHHHHHHHHHHHT CS
  Ribosomal_S7  92 rpkRrqalAlrwiieaarkrkeksmaekLaeElidAaegegaavkkreethrmAean 148
                   ++++r+++A+rwi+eaa+krk+ ++a ++a+El+++aeg++++++kre +h++  a 
    EEA21667.1 295 AMRQRRRTAIRWILEAAEKRKDSKLAVRVANELLAVAEGRSGVWEKREHVHKIGVAG 351
                   ****************************************************98775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (364 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       442  (0.0246528); expected 358.6 (0.02)
Passed bias filter:                      352  (0.019633); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.48
# Mc/sec: 2298.57
//
Query:       EEA21668.1  [L=427]
Description: calcium ion transporter Vcx1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      3e-42  144.1  40.0    3.9e-21   75.6  18.2    2.3  2  Na_Ca_ex  Sodium/calcium exchanger protein


Domain annotation for each model (and alignments):
>> Na_Ca_ex  Sodium/calcium exchanger protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.4  13.8     5e-25   8.9e-21       3     150 ..      80     240 ..      78     241 .. 0.90
   2 !   75.6  18.2   2.2e-25   3.9e-21       4     150 ..     278     419 ..     275     420 .. 0.92

  Alignments for each domain:
  == domain 1  score: 74.4 bits;  conditional E-value: 5e-25
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCTHHHHHHHHHHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHHHTHHHHHHHHHHBTTSSCECCH CS
    Na_Ca_ex   3 fvlfilslllisvladflvssaeeiakslgisgsvlGltllAlgnslpElissiiaaltgevdlaignvlGsnifnlllviGlialigslkvdseslkl 101
                 + +f+l +l+i++la++l+ ++ee+a      g++lG +++A+++++ Eli+siia++ ++++++ +++lGs++ n+llv+G+++l+g+  + +e+ ++
  EEA21668.1  80 ATVFVLNFLAIMPLASLLSFATEELA---ATMGQTLGGLMNATFGNAVELIVSIIALKDNQIRVVQASMLGSILSNILLVLGCCFLVGG-LRFPEQ-EF 173
                 679***********************...89999*******************************************************.555555.66 PP

                 HHHHHHHHHHHHHHHHHHTCHHHHH..................HTEEHHHHHHHHHHHHHHHHHHHH CS
    Na_Ca_ex 102 dlgllllvallllllvlllllplfv..................pgrltvleglvllllYalylvlsl 150
                 +  + ++++ l+ ++ + l++p+++                     l++ ++++llllY++ylv++l
  EEA21668.1 174 NSTVASTMSSLMAVASASLIIPASLfaamsdsyqtapedsrrsILLLSRGTAIILLLLYVMYLVFQL 240
                 66666666666666677778888778999999********999999*******************98 PP

  == domain 2  score: 75.6 bits;  conditional E-value: 2.2e-25
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHTTCTHHHHHHHHHHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHHHTHHHHHHHHHHBTTSSCECCHH CS
    Na_Ca_ex   4 vlfilslllisvladflvssaeeiakslgisgsvlGltllAlgnslpElissiiaaltgevdlaignvlGsnifnlllviGlialigslkvdseslkld 102
                 +++i+ ++l+s++a++lv s+e i++++g+s++++Gl+l+++++++ E+++++++  ++++dlaig ++Gs +++ l+v ++ +++g+  + + +++l+
  EEA21668.1 278 IALIIVTVLVSICAEYLVGSIEGIVEKTGMSKTFIGLVLIPIVGNAAEHVTAVVVSYKNKMDLAIGVAIGSSLQIALFVTPFLVILGW--IMNVEMTLH 374
                 678999********************************************************************************99..444457899 PP

                 HHHHHHHHHHHHHHHHHTCHHHHHHTEEHHHHHHHHHHHHHHHHHHHH CS
    Na_Ca_ex 103 lgllllvallllllvlllllplfvpgrltvleglvllllYalylvlsl 150
                 + ++ +v++++++lv+++l+     g+ ++leg ++l++Ya+ ++ ++
  EEA21668.1 375 FHIFETVSFFISALVVIFLIQD---GKSNYLEGGLCLGMYAILAIAFY 419
                 999******9999888877665...****************9987665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (427 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1120  (0.0624686); expected 358.6 (0.02)
Passed bias filter:                      441  (0.024597); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.44
# Mc/sec: 2902.37
//
Query:       EEA21669.1  [L=864]
Description: endo-1,3-beta-glucanase Engl1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.4e-164  547.5   5.3   1.8e-164  547.0   5.3    1.2  1  Glyco_hydro81C  Glycosyl hydrolase family 81 C-terminal domai
   5.1e-112  374.2   0.0   7.3e-112  373.7   0.0    1.2  1  Glyco_hydro_81  Glycosyl hydrolase family 81 N-terminal domai


Domain annotation for each model (and alignments):
>> Glyco_hydro81C  Glycosyl hydrolase family 81 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  547.0   5.3  2.1e-168  1.8e-164       2     349 .]     500     854 ..     499     854 .. 0.98

  Alignments for each domain:
  == domain 1  score: 547.0 bits;  conditional E-value: 2.1e-168
  Glyco_hydro81C   2 lseealkaiaeaaekelkqdlsaesnldsmYfsGKalakfatlvyvvkellkdeelakaalkkLkealerflenkqklplvYdekwkGvvssagy 96 
                     ls++++++i +aa  el+ d++++snl+smY+sGK+l+kfatlvy+v++l +d + a+ +++ Lk+a++rf++n+q++plvYd++wkGvvssa+y
      EEA21669.1 500 LSSDVQQTISSAADIELTPDIDHQSNLNSMYYSGKVLSKFATLVYAVHKLANDPDRAAPTFDGLKKAFARFVNNEQQFPLVYDNTWKGVVSSAAY 594
                     78999****************************************************************************************** PP

  Glyco_hydro81C  97 kt.dsgaDFGntlyNDHhfHygYfvyaaaviakldpswlek.nkewvntLvrDvanpseedeyfpvsRsfDwyhgHSwakGlfesadGkdqEsss 189
                     +t d ++DFGn+ yNDHhfHygYf++aaa+i++ldpswl++ nk+wvn+LvrD+ np ++d+ fp+sR+fDwyhgHSwakGlfesadGkdqEs+s
      EEA21669.1 595 ETnDLNQDFGNSGYNDHHFHYGYFIHAAAIIGSLDPSWLTDdNKAWVNMLVRDAGNPASNDPSFPFSRAFDWYHGHSWAKGLFESADGKDQESTS 689
                     *99************************************988***************************************************** PP

  Glyco_hydro81C 190 EdvnaayalklwGkvigdasleargnlmlaiearslqkyflleednkvqpkefignkvaGilfenkvdhttyFgankeyiqgihmlPllpvseli 284
                     Ed+++aya+k+wGk+igd+s+eargnlmla+ +rsl++yfl+e dn+++p++fignkv+Gilfenk +httyFgan e+iqgihmlPllp s+++
      EEA21669.1 690 EDAMFAYAVKMWGKTIGDNSMEARGNLMLALLKRSLKHYFLMEGDNSNHPSNFIGNKVTGILFENKAHHTTYFGANLEFIQGIHMLPLLPSSAYT 784
                     *********************************************************************************************** PP

  Glyco_hydro81C 285 rskkfvkeeweallae....raekv.eegWkgilyanlalvdpkaayeffsseefkeklldgGasrtWyl 349
                     r+++fv++ew+a+++e     a++v ++gWkg+lyan+a++dp++ay+ffs+++f+ +++dgGa+rtWyl
      EEA21669.1 785 RNEAFVRQEWDAIFSEgacaPASAVsSGGWKGVLYANQAIIDPAKAYDFFSQPNFNMTWIDGGATRTWYL 854
                     ****************9988677774789****************************************8 PP

>> Glyco_hydro_81  Glycosyl hydrolase family 81 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  373.7   0.0  8.1e-116  7.3e-112       1     323 []     163     492 ..     163     492 .. 0.95

  Alignments for each domain:
  == domain 1  score: 373.7 bits;  conditional E-value: 8.1e-116
  Glyco_hydro_81   1 hpvppsgvsesdkpleTNkFYaNllLgdqtqpvythPYslkwskg....kswGlavshteasqrvfgpdk...saepasyyvnPigiqslvlsaa 88 
                     hpvp+ g+ e+++p+eTNkFY+N+lLg+qt+  ++hPY l w +g    +swGla+sht+ +q+v+g+++   +++p++yy+nPig qs++lsa+
      EEA21669.1 163 HPVPKVGIVETTAPIETNKFYTNFLLGNQTTYSFVHPYALGWPRGsgnaQSWGLAISHTDIDQLVYGNQSaqlPENPVEYYLNPIGFQSVILSAS 257
                     9******999********************************99889988******************9999999******************** PP

  Glyco_hydro_81  89 elssstsltvsslkdlsvtvelsasksssssirfpLvqGmgFvTaiysnltpviqsgvgfksveagssvkssvvtkyrvkledgqtWllYatpes 183
                     el+ st l+++ l+ lsv+v l++s++ s+si+fp+ qGmgFvT+iy++l+p++qs ++f+++  +   ++++ +kyrv+l dg++Wl Y+tp++
      EEA21669.1 258 ELGPSTILNTDRLTGLSVDVILRPSNQPSKSITFPVLQGMGFVTGIYTGLQPLVQSCITFRDLVCVGAIGQGT-YKYRVTLADGKSWLFYVTPDN 351
                     *************************888***********************************9999999999.*******************99 PP

  Glyco_hydro_81 184 ....ssdleltlesnstiegskefsGiiqvaklpgedseseavlDeaagvYatgaelsgsvsgeatgsYsfkykkeGkseesgkllmfalPhhle 274
                         +  ++++  s++ti+g+++fsGiiqvak p +  + e+v+D +agvYa +a++sg+vs+  tg+Y ++++k+G+s+ +++ll+falPhh+e
      EEA21669.1 352 ddglNPVFSFNE-SSTTIKGPMGFSGIIQVAKNP-AGLTGETVYDGSAGVYARSASISGAVSDY-TGTYGLTWEKAGQSAANKPLLTFALPHHVE 443
                     774444444444.999****************77.445557**********************9.9*************999************* PP

  Glyco_hydro_81 275 sldeetkarvtklklrsttkGemtavlgdswtleetnlpvelgfaPwss 323
                     s+d++t+a+++ l+lrsttkG+m+av++d+wt++e+nlp+++gfaPws+
      EEA21669.1 444 SFDAQTRAALQPLQLRSTTKGNMSAVAADKWTMVESNLPIDIGFAPWSP 492
                     ***********************************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (864 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       309  (0.0172346); expected 358.6 (0.02)
Passed bias filter:                      253  (0.0141112); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.27s 00:00:00.90 Elapsed: 00:00:00.44
# Mc/sec: 5950.94
//
Query:       EEA21670.1  [L=969]
Description: small nucleolar ribonucleoprotein complex subunit Utp14, putatrive [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   4.4e-217  723.3  67.7   4.4e-217  723.3  67.7    2.0  2  Utp14     Utp14 protein


Domain annotation for each model (and alignments):
>> Utp14  Utp14 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?  -10.4  23.3         1   1.8e+04     376     549 ..      22     208 ..       3     226 .. 0.29
   2 !  723.3  67.7  2.4e-221  4.4e-217       2     756 .]     227     967 ..     226     967 .. 0.79

  Alignments for each domain:
  == domain 1  score: -10.4 bits;  conditional E-value: 1
       Utp14 376 eeepekgllamkFmkra...earkkeendeeieel.rrelekgdeeeedeeeeeeeekesknvGrrvfgpskkskkkekkkkkkeskakkekreeeeed 470
                 + + +kgl a+++ + +   + + ++    e+e++ + + +++++e+e +++   ++++ ++ G   +g++++ ++ +  + +   ++++++ +++e+ 
  EEA21670.1  22 QRKRNKGLNALAIAEHEfptQTKVRAHRLGEVEDFpK-RRRNDEDEDEPDTKRRRTDEDGASEG--DYGSDSEGHEWKIGQVD---SEDDSDIDSDEAL 114
                 4555555555555555411133333444555555542.22222222222221111112222222..35554422222222222...1111111111111 PP

       Utp14 471 eskaaeekakke...........kskksekkkkkk..keesakeeeeeeeenpwlae....e......ekkkskkeevaaekssskakkskakakkkkk 546
                  ++++ e    +           k   s++k+++k  + +++k + +e++ + + ++    +      +++      +  ++++ ++ k+ +k +kk k
  EEA21670.1 115 GESDE-E----RfedftfrgsssK---SNAKSERKpkTVKRQKIDLSEGSGSDFESDqedyDddlgedAVDLATAWDMNGGEDEDENGKATSKTSKKPK 205
                 11111.1....1222334443221...222211111122222223333333333222222202222221111111222222222222222222222222 PP

       Utp14 547 kss 549
                 k++
  EEA21670.1 206 KRQ 208
                 222 PP

  == domain 2  score: 723.3 bits;  conditional E-value: 2.4e-221
       Utp14   2 edeeedeeeelsdded...edeekhskLlklissldk....kkkkkkkeekeeseeesefnlsseskgklslsdLlaplekskdselkkslklleke.. 91 
                 +de+e+e+ ++s+++d   e e+ +skL++++ssl++    ++ +++k + +e+++++e++l+s  ++kl++sdLl++++   ds+lk slk+l+++  
  EEA21670.1 227 SDEDESEDTDISMSDDevdEKEDGLSKLQDFVSSLGTsnagTTSQQRKIKGQENGAPTEYGLTS--TRKLNVSDLLSSVT---DSRLKGSLKHLSSTtt 320
                 677777888888888877767999*************665533667777999**********55..8*********9997...8**********888** PP

       Utp14  92 ......kkkkklaaPLpkrqqdrleRkaAyektkeeldkWedtVkrnrraehLsFplqqdkkkekktlaalaskfkprtelekkiasileesgla.... 180
                       ++++kl aPL+krqqd+++R+aAyek+ke+l++W dtVk+nr+aeh+sFpl+++ +++  +l ++    +p+t+le++i+sil esgla    
  EEA21670.1 321 gqgaksSAPGKLTAPLAKRQQDKIDRTAAYEKSKETLNRWIDTVKANREAEHISFPLPDPHEQQVARLGPV----EPKTDLESTIKSILVESGLAtdek 415
                 *****999***************************************************887766666666....********************9999 PP

       Utp14 181 .eekklekaeelalnklsleevkerraelrkmRellfreeakakRikKIKSKtYrRihrKekekeeekeeealeetdpeaale.ds.erekqerkRaeE 276
                   ek+ ++aeel+++k+sleev++r  elrk R+llfree++akRikKIKSK+YrR+hrKe+ek ee e++al +    a+ + d+ ere  +r+Rae 
  EEA21670.1 416 tAEKQFQAAEELETRKMSLEEVRARNIELRKRRDLLFREEVRAKRIKKIKSKSYRRVHRKEREKLEEVERQALID----AGIDpDEqERELYDRRRAEA 510
                 9999999******************************************************************99....67665557************ PP

       Utp14 277 RmtlKHkntSkWAKsikktgrakwdeeaReaiaeqlrrgeeLrrkiegkeededddddsdedssdseeeedn.seedaeeekrkkleklkeeeeke... 371
                 Rm++KH++ SkWAKs+k+tgr++wde+aR+ +++++rr+ eL+++ieg+++  d dd   ++ss+se+++d+ +ee++++ +++ l+k  +    +   
  EEA21670.1 511 RMSTKHRD-SKWAKSMKETGRTAWDEDARSSMHDMARRDVELQKRIEGRNVKADGDDYLGSSSSESEDNHDEwDEEADSDAEARILNKDLD----Alig 604
                 ********.****************************************887777666444444444443443223333334444444222....2233 PP

       Utp14 372 .eeeeeeepekgllamkFmkraearkkeendeeieelrrelekgdeeeedeeeeeeeekesknvGrrvfgpskkskkkekkkkkkeskakkekreeeee 469
                  +++e+++p+++l++m Fm++aea +k++ndeei++lrre++ gde+e++ee       e    Gr++fg sk ++k++ ++++++++ +++ ++e+ee
  EEA21670.1 605 lDDSESTGPHSKLMGMSFMQKAEAGRKQQNDEEIRKLRREINGGDEDESEEE-------E---GGRMKFGGSKPAEKQTLAASRSKNEFEETVASEDEE 693
                 4577899***********************************7766655555.......3...8*********88777777777777777777777666 PP

       Utp14 470 deskaaeekakke..........kskksekkkkkk.keesakeeeeeeeenpwlaeeekkkskkeevaaekssskakkskakakkkkkksskkkeaake 557
                   ++a+++ ++            ++++  +k++k+ +  +a+e++++e enpw                      +++++++++++++++++ + +  +
  EEA21670.1 694 PGNEATSAPEH-GsnsynkgsskTKRSVDTKSAKAsEYRPAMEDSDKEIENPW--------------------LVQNTRANRKRQTNDADESINISVGD 771
                 65555333332.13555555543222222222222233444555555555555....................55555544444444444443333222 PP

       Utp14 558 kkkkdeeidlkkketlkekekt.lkkkk......kedkeeesdddeeeeeevelpvalkqreliaeAFAgDDVvaeFekEKkevveeedpkevdktLPG 649
                   ++++++   +k++     ++ +k+++      ++d+e+ sd+d+     ++ pv +++++l+++AFAgDDVva+Fe+EK+e++eee++k++d+tLPG
  EEA21670.1 772 --QEQAAVSNASKVSSG---QKpQKASSlkyhisTQDNESGSDSDD-----ENVPVLFTNHDLVKRAFAGDDVVADFEREKQETIEEEGDKVIDNTLPG 860
                 ..222222211111111...11111111112222233333333333.....23799******************************************* PP

       Utp14 650 WGsWaGegvkkrkkkkr.kflkkvegvkkkkRkDaklknVIInEkrdkkaakylvsqLPfpFeskeqYErslrlPlGpeWntketfqkltkPrVvvkqG 747
                 WGsW+G+g++k+++k++ kfl+kveg+k+++RkDa+l +VIInEkr kk+ ky+++qLP+pFe+++qYErslr+P+GpeW+t+ tf+++tkPrV++kqG
  EEA21670.1 861 WGSWTGAGISKKQQKRQkKFLTKVEGIKPEQRKDARLGHVIINEKRMKKNVKYMATQLPHPFETRQQYERSLRQPIGPEWSTSDTFHEATKPRVLIKQG 959
                 *************886679******************************************************************************** PP

       Utp14 748 avIkPlkkp 756
                  +IkP+++p
  EEA21670.1 960 -IIKPMQRP 967
                 .*****997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (969 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1493  (0.0832729); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 1.11u 0.34s 00:00:01.45 Elapsed: 00:00:00.58
# Mc/sec: 5042.71
//
Query:       EEA21671.1  [L=162]
Description: 50S ribosomal protein YmL27 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-13   50.2   0.2    3.3e-13   49.4   0.2    1.3  1  MRP-L27   Mitochondrial ribosomal protein L27


Domain annotation for each model (and alignments):
>> MRP-L27  Mitochondrial ribosomal protein L27
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.4   0.2   1.9e-17   3.3e-13       6      70 ..      10      75 ..       8      89 .. 0.90

  Alignments for each domain:
  == domain 1  score: 49.4 bits;  conditional E-value: 1.9e-17
                SS---TTSS-HHHH---S---SEEEETTTEEEE-TTTS-EE----.-TT----SEE-TTS------ CS
     MRP-L27  6 rveltsKrGnktfykgrgargiGiltssgkyveirekvrelvvPd.legfkLKpyVsykapevkqs 70
                r+ lt+K+ n+ +ykg +   +G+  ++g y+++ +k r++vvP+ l+ fkL p+V +     + +
  EEA21671.1 10 RLRLTTKQVNRGYYKGNRTGSMGFFLKTGTYIIDPSKLRTYVVPEnLDSFKLTPFVTKSFLPTRTK 75
                789*****************************************99**********9887666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (162 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       871  (0.0485805); expected 358.6 (0.02)
Passed bias filter:                      464  (0.0258799); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1132.31
//
Query:       EEA21672.1  [L=1217]
Description: IQ and HECT domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.7e-84  281.8   0.0    1.2e-83  281.2   0.0    1.3  1  HECT      HECT-domain (ubiquitin-transferase)
     0.0034   17.0   1.1      0.014   15.1   1.1    2.2  1  IQ        IQ calmodulin-binding motif


Domain annotation for each model (and alignments):
>> HECT  HECT-domain (ubiquitin-transferase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  281.2   0.0   1.3e-87   1.2e-83       3     307 .]     873    1217 .]     871    1217 .] 0.92

  Alignments for each domain:
  == domain 1  score: 281.2 bits;  conditional E-value: 1.3e-87
                  HHHHHT-GGGSSEEESSTTSSSEEE-TTHHHHS..........................HHHHHHHHHHHHHTT--BSS-B-HHHHHHHTT...... CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...... RF
        HECT    3 lskelldpklglfeeesedsgtlypkpssseee......................llklfeflGkvlGkaiyeeilldlpfsraflkfllg...... 71  
                  +++e++ p+ gl    ++d++ lyp+p++ e++                      llk +eflG+v+Gk++ye+il+d++f+ +fl ++        
  EEA21672.1  873 ITNEAFMPSNGLDLFVENDQNLLYPNPTAVEQRkeilrqigctegspqfvdgvrdLLKRYEFLGRVVGKCLYEGILVDVHFAGFFLLKWALtggsts 969 
                  677877777655444699999******9877779*********************8899**************************99887779**** PP

                  .....-.---TCHHHHH-HHHHHHHHHHH..HS-GGG...GT-BSEEEEE..T.TEEE...EEESSTTGGGSB--TTTHHHHHHHHHHHHHTGGGHH CS
                  .....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..x.xxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        HECT   72 .....eekitledleeidpelakslkellslesnteevedlaLtFtipen..a.gasa...tieLipnGanipVtnenkkeYiklyvnyllkksvek 157 
                        ++ +l+dl+++d+ l++ l +l+++     +ved++L+Ft++ +  + g++    t +L+p+Gani Vtn+n+  Yi+ +++++l+++ ++
  EEA21672.1  970 arresAYRANLNDLRDLDEGLYQGLLQLKNY--PG-DVEDFSLNFTVTDTipIpGSKPriiTKDLKPGGANIAVTNQNRLVYISYIARHRLQNQPAP 1063
                  ****97899********************66..43.49********998765456664688999********************************* PP

                  HHHHHHHHHHTTS-HHHHTTS-HHHHHHHHBCSSS.--HHHHHHTEEEETT-.....-TTSHHHHHHHHHHHHS-HHHHHHHHHHHHSSSS--TTCG CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        HECT  158 qleaflkGfsevipskalklfdaeelellisGedelidvedlrrnteykggy.....naesetiewlweilkefspeekrlfLqFvTgssrlPlgGf 249 
                  q++aflkG+ e+i+ ++l++f+++el++l+ G++  idv dlrrnt y+g y     n+e++ti+++w++++e+s+ee+++ L+FvT+++r+Pl Gf
  EEA21672.1 1064 QTNAFLKGLGEIIQPSWLSMFNQSELQTLVGGDAGEIDVADLRRNTLYGGVYvigddNQEHPTIQLFWQVMQELSNEERQKVLKFVTSTPRAPLLGF 1160
                  **********************************88************9998555556999************************************ PP

                  GG-B--EEEEE-S..-TTS--EEEGGGTEEEE---SSHHHHHHHHHHHHHHHH--XXX CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        HECT  250 aelhpkftierkskedetrLPtahTCfnlLklpdYsskeilkekLltAieetegFels 307 
                  ++l+p+f i+ +s +d++rLP+ +TC+nlLklp+Ys++ +l++kLl+A+++++gF+ls
  EEA21672.1 1161 SHLNPRFSIRDSS-DDQDRLPSTSTCVNLLKLPRYSNAHTLRQKLLYAVNSGAGFDLS 1217
                  ***********87.9*****************************************96 PP

>> IQ  IQ calmodulin-binding motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   1.1   1.6e-06     0.014       3      20 ..      64      81 ..      62      82 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 1.6e-06
                HHHHHHHHHHHHHHHHHH CS
          IQ  3 aaikIQaawRGylaRkry 20
                +a ++Q+ wRGyl R++ 
  EEA21672.1 64 SARLLQRTWRGYLSRRAA 81
                7789************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1217 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       494  (0.0275531); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.80u 0.31s 00:00:01.11 Elapsed: 00:00:00.49
# Mc/sec: 7522.41
//
Query:       EEA21673.1  [L=748]
Description: polyadenylate-binding protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      6e-81  266.3   6.6    2.2e-21   75.4   0.2    5.4  5  RRM_1         RNA recognition motif. (a.k.a. RRM, RBD, or RNP
    1.7e-29  101.8   0.7    1.2e-28   99.0   0.9    2.3  2  PABP          Poly-adenylate binding protein, unique domain
    2.2e-15   56.4   0.2     0.0018   17.9   0.0    5.2  5  RRM_5         RNA recognition motif. (a.k.a. RRM, RBD, or RNP
    0.00014   21.9   2.0        6.4    7.0   0.0    5.4  4  RRM_7         RNA recognition motif
    0.00049   20.2   0.0        3.3    7.9   0.0    3.5  3  CbiG_mid      Cobalamin biosynthesis central region
    0.00064   19.7   1.1         14    5.8   0.0    4.5  4  Nup35_RRM_2   Nup53/35/40-type RNA recognition motif
     0.0013   19.2   2.1       0.14   12.7   1.0    2.9  2  YflT          Heat induced stress protein YflT
  ------ inclusion threshold ------
      0.016   15.2   2.3        8.4    6.5   0.1    3.6  3  Limkain-b1    Limkain b1
      0.027   14.3   0.0         21    5.1   0.0    3.2  3  RRM_occluded  Occluded RNA-recognition motif
       0.18   11.5   3.5         15    5.3   0.0    3.5  3  OB_RNB        Ribonuclease B OB domain
       0.38   10.6   3.4         63    3.5   0.1    3.5  3  CSD           'Cold-shock' DNA-binding domain
        1.3   10.1   5.1        0.5   11.3   1.4    2.2  2  DUF4834       Domain of unknown function (DUF4834)


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.0   0.0   1.1e-20   1.7e-17       1      69 [.      52     121 ..      52     122 .. 0.98
   2 !   64.4   0.3   4.3e-21   6.4e-18       1      68 [.     140     207 ..     140     208 .. 0.98
   3 !   75.4   0.2   1.5e-24   2.2e-21       1      69 [.     233     301 ..     233     302 .. 0.98
   4 !   34.0   0.0   1.3e-11   1.9e-08       1      33 [.     336     368 ..     336     376 .. 0.92
   5 !   28.7   0.1   5.7e-10   8.5e-07      34      69 ..     415     450 ..     406     451 .. 0.91

  Alignments for each domain:
  == domain 1  score: 63.0 bits;  conditional E-value: 1.1e-20
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrel 69 
                 l+Vg L p+vte +L elFs +G++ si+++rd  t++s g+a+V++++  d e+Ale ln + ++gr++
  EEA21673.1  52 LYVGELDPSVTEAMLFELFSSIGQVASIRVCRDaVTRRSLGYAYVNYNNTADGERALEDLNYTLIKGRPC 121
                 8******************************************************************987 PP

  == domain 2  score: 64.4 bits;  conditional E-value: 4.3e-21
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkklggre 68 
                 +f++nL + ++++ L++ F  fG i s+k+  de g+skg++fV +e+ e+A++A++++ng+ l++++
  EEA21673.1 140 VFIKNLDTAIDNKALHDTFAAFGNILSCKVAQDEFGNSKGYGFVHYETAEAANNAIKHVNGMLLNDKK 207
                 8****************************************************************997 PP

  == domain 3  score: 75.4 bits;  conditional E-value: 1.5e-24
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkklggrel 69 
                 ++V+n+ p+vt+ee +elF+kfG+i+s++++rd  gks+gf+fV++ ++e+A+ A++ ln k ++g++l
  EEA21673.1 233 VYVKNIDPEVTDEEFRELFGKFGDITSATISRDDSGKSRGFGFVNYVDHENAQTAVDDLNDKDFHGQKL 301
                 8*****************************************************************987 PP

  == domain 4  score: 34.0 bits;  conditional E-value: 1.3e-11
                 EEEESETTTSSHHHHHHHHHTTSCEEEEEEEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFskfGpiksiklvrd 33 
                 l+V+nL+ dv++e+L+elFs fG i+s+k++rd
  EEA21673.1 336 LYVKNLTDDVDDEKLRELFSAFGTITSAKVMRD 368
                 8*******************************9 PP

  == domain 5  score: 28.7 bits;  conditional E-value: 5.7e-10
                 TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1  34 etgkskgfafVeFeskedAekAlealngkklggrel 69 
                   gkskgf+fV F s+++A kA+ ++n ++++g++l
  EEA21673.1 415 VFGKSKGFGFVCFSSPDEASKAVTEMNQRMVNGKPL 450
                 679******************************987 PP

>> PABP  Poly-adenylate binding protein, unique domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0       1.8   2.7e+03      30      41 ..     189     204 ..     161     220 .. 0.74
   2 !   99.0   0.9   8.2e-32   1.2e-28       3      68 .]     653     718 ..     651     718 .. 0.97

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 1.8
        PABP  30 elAg....KITGMLLe 41 
                 e A+    ++ GMLL 
  EEA21673.1 189 EAANnaikHVNGMLLN 204
                 44445555899***97 PP

  == domain 2  score: 99.0 bits;  conditional E-value: 8.2e-32
        PABP   3 elakaspeqqkqiLGerLypkiqklnpelAgKITGMLLemdnsellellesdeeLrekveeAievl 68 
                 +l++a+p+qqkq+LGe Lypkiq+++pelAgKITGMLLemdn+ell l++++ +Lr+kv+eA+ v+
  EEA21673.1 653 ALTAAPPQQQKQMLGEALYPKIQAQQPELAGKITGMLLEMDNAELLGLIDDESALRAKVDEALHVY 718
                 6899***********************************************************985 PP

>> RRM_5  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.0   1.2e-06    0.0018       2     101 ..      27     128 ..      26     134 .. 0.84
   2 !   12.5   0.4   5.6e-05     0.083      28     103 ..     139     219 ..     130     232 .. 0.79
   3 !   12.1   0.0   7.2e-05      0.11      31     102 ..     235     309 ..     220     327 .. 0.78
   4 ?    2.8   0.0     0.057        84      25      63 ..     332     369 ..     314     373 .. 0.79
   5 ?    4.1   0.0     0.022        33      64     108 ..     420     464 ..     413     475 .. 0.83

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 1.2e-06
       RRM_5   2 arlvpsllasvaatgspgaagvaegsVllVyglepdkvnldklFnlfclYgnvervkflk.....tkketalvqmgdasaveravqHLnnaklfgkrle 95 
                 +++vp++ as aat+      +++++ l V  l+p+ v+  +lF lf+  g+v+ +++ +        ++a v+  ++ + era++ Ln + + g++ +
  EEA21673.1  27 TNVVPDTAASDAATTP--NPNQPHSASLYVGELDPS-VTEAMLFELFSSIGQVASIRVCRdavtrRSLGYAYVNYNNTADGERALEDLNYTLIKGRPCR 122
                 5788999999999998..555666999*******97.7889***************9976222114569***************************999 PP

       RRM_5  96 valSKq 101
                 ++ S +
  EEA21673.1 123 IMWSQR 128
                 999976 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 5.6e-05
       RRM_5  28 VllVyglepdkvnldklFnlfclYgnvervkflk....tkketalvqmgdasaveravqHLnnaklfgkrlev..alSKqqa 103
                  +++ +l++  +  + l   f+ +gn+   k+ +    + k++ +v    a a++ a++H+n+  l +k++ v   +SK++ 
  EEA21673.1 139 NVFIKNLDTA-IDNKALHDTFAAFGNILSCKVAQdefgNSKGYGFVHYETAEAANNAIKHVNGMLLNDKKVFVghHISKKDR 219
                 4567888865.67789999*********9999653333789****************************8766225788765 PP

  == domain 3  score: 12.1 bits;  conditional E-value: 7.2e-05
       RRM_5  31 VyglepdkvnldklFnlfclYgnvervkflktkk....etalvqmgdasaveravqHLnnaklfgkrlevalSKqq 102
                 V +++p+ v+ ++   lf+ +g++    + +       +  +v+  d  ++++av+ Ln++  +g++l v    ++
  EEA21673.1 235 VKNIDPE-VTDEEFRELFGKFGDITSATISRDDSgksrGFGFVNYVDHENAQTAVDDLNDKDFHGQKLYVGRAQKK 309
                 6666664.5666777899999999999999876511115679**************************99765443 PP

  == domain 4  score: 2.8 bits;  conditional E-value: 0.057
       RRM_5  25 egsVllVyglepdkvnldklFnlfclYgnvervkflktk 63 
                 +g  l V +l  d v  +kl  lf+ +g +   k+++  
  EEA21673.1 332 QGVNLYVKNLT-DDVDDEKLRELFSAFGTITSAKVMRDT 369
                 55557788885.67999*******************975 PP

  == domain 5  score: 4.1 bits;  conditional E-value: 0.022
       RRM_5  64 ketalvqmgdasaveravqHLnnaklfgkrlevalSKqqavseke 108
                 k+  +v  ++  ++ +av+ +n   + gk+l val  ++ v +++
  EEA21673.1 420 KGFGFVCFSSPDEASKAVTEMNQRMVNGKPLYVALAQRKDVRKSQ 464
                 66677778888899**********************999987654 PP

>> RRM_7  RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.0      0.17   2.6e+02       2      29 ..      50      77 ..      49     109 .. 0.78
   2 !    7.0   0.0    0.0043       6.4       4      65 ..     140     193 ..     137     220 .. 0.74
   3 ?    2.6   0.0     0.097   1.5e+02       4      30 ..     233     259 ..     231     314 .. 0.73
   4 ?    3.5   0.3     0.052        77       8      29 ..     340     361 ..     334     467 .. 0.72

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.17
       RRM_7  2 rkvFvGGlPiDiteeelkatfkefgkvl 29
                  ++vG l + +te+ l + f++ g+v+
  EEA21673.1 50 ASLYVGELDPSVTEAMLFELFSSIGQVA 77
                56899*****************999875 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0043
       RRM_7   4 vFvGGlPiDiteeelkatfkefgkvlvdwPkkaeskkkaaenskaakgyvflvfedeksvka 65 
                 vF+  l + i++++l++tf +fg++l        +k ++  +    kgy f+ +e+ ++ ++
  EEA21673.1 140 VFIKNLDTAIDNKALHDTFAAFGNILS-------CKVAQD-EFGNSKGYGFVHYETAEAANN 193
                 99999******************9863.......111111.223346777777777766655 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.097
       RRM_7   4 vFvGGlPiDiteeelkatfkefgkvlv 30 
                 v+v  + +++t+ee  + f++fg+++ 
  EEA21673.1 233 VYVKNIDPEVTDEEFRELFGKFGDITS 259
                 788889999**************9864 PP

  == domain 4  score: 3.5 bits;  conditional E-value: 0.052
       RRM_7   8 GlPiDiteeelkatfkefgkvl 29 
                  l  D+++e+l + f++fg+++
  EEA21673.1 340 NLTDDVDDEKLRELFSAFGTIT 361
                 5667888888888888888764 PP

>> CbiG_mid  Cobalamin biosynthesis central region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0     0.036        53      12      54 ..     100     142 ..      90     155 .. 0.83
   2 ?    3.7   0.0     0.043        65      15      38 ..     190     213 ..     169     239 .. 0.74
   3 !    7.9   0.0    0.0022       3.3      15      45 ..     432     462 ..     415     494 .. 0.71

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.036
    CbiG_mid  12 wriegegaltevsaalvngepvavlqdvrlegterlertlpeh 54 
                  + +ge+al +++ +l++g+p  +++ +r++  ++  + +  +
  EEA21673.1 100 NTADGERALEDLNYTLIKGRPCRIMWSQRDPALRKTGQGNVFI 142
                 566899********************99999888877766655 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.043
    CbiG_mid  15 egegaltevsaalvngepvavlqd 38 
                 + + a+++v+++l+n+++v v  +
  EEA21673.1 190 AANNAIKHVNGMLLNDKKVFVGHH 213
                 56789*************987664 PP

  == domain 3  score: 7.9 bits;  conditional E-value: 0.0022
    CbiG_mid  15 egegaltevsaalvngepvavlqdvrlegte 45 
                 e  +a+te+++++vng+p  v + +r    +
  EEA21673.1 432 EASKAVTEMNQRMVNGKPLYVALAQRKDVRK 462
                 56789*************8888744433333 PP

>> Nup35_RRM_2  Nup53/35/40-type RNA recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0       0.3   4.5e+02      21      53 .]      70     108 ..      63     108 .. 0.75
   2 ?    3.9   0.1     0.037        56      21      52 ..     158     194 ..     155     195 .. 0.90
   3 ?    3.7   0.0     0.041        62      17      53 .]     247     288 ..     238     288 .. 0.88
   4 !    5.8   0.0    0.0094        14      31      53 .]     415     437 ..     347     437 .. 0.87

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.3
  Nup35_RRM_2  21 FasfGeIvkhyvp......kevsvmyvkfesekdaekAL 53 
                  F s+G++  + v       ++  ++yv + +  d e+AL
   EEA21673.1  70 FSSIGQVASIRVCrdavtrRSLGYAYVNYNNTADGERAL 108
                  5566666666666666655555689***********998 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.037
  Nup35_RRM_2  21 FasfGeIvkhyvp.....kevsvmyvkfesekdaekA 52 
                  Fa fG+I    v      +++ + +v +e+  +a+ A
   EEA21673.1 158 FAAFGNILSCKVAqdefgNSKGYGFVHYETAEAANNA 194
                  899*****988877888899**************998 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.041
  Nup35_RRM_2  17 VlehFasfGeIvkhyvp.....kevsvmyvkfesekdaekAL 53 
                   +e F  fG I+   ++     k++ + +v + +  +a++A+
   EEA21673.1 247 FRELFGKFGDITSATISrddsgKSRGFGFVNYVDHENAQTAV 288
                  5677999******88888899999****************98 PP

  == domain 4  score: 5.8 bits;  conditional E-value: 0.0094
  Nup35_RRM_2  31 yvpkevsvmyvkfesekdaekAL 53 
                   ++k++ + +v+f s+++a kA+
   EEA21673.1 415 VFGKSKGFGFVCFSSPDEASKAV 437
                  455889999*************8 PP

>> YflT  Heat induced stress protein YflT
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   1.0   9.5e-05      0.14       5      79 ..     279     358 ..     277     364 .. 0.84
   2 ?    4.1   0.0     0.043        65       4      51 ..     427     474 ..     425     486 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 9.5e-05
        YflT   5 eneeellsaieelkaeGyneddiyv..vakdkdrlerlaentdaetettse..eglwdsiknlfrs.kgdelrekleslG 79 
                  + e ++ a+++l++++++ +++yv  + k+ +r e+l+++++a   ++++  +g+   +knl    ++++lre ++ +G
  EEA21673.1 279 VDHENAQTAVDDLNDKDFHGQKLYVgrAQKKHEREEELRRQYEAARLEKASkyQGVNLYVKNLTDDvDDEKLRELFSAFG 358
                 57899********************66678888999*******9999988889999999999998845555666666665 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.043
        YflT   4 yeneeellsaieelkaeGyneddiyvvakdkdrlerlaentdaetett 51 
                 +++ +e+ +a+ e+++  +n + +yv+  +++++++ + ++ +++ +t
  EEA21673.1 427 FSSPDEASKAVTEMNQRMVNGKPLYVALAQRKDVRKSQLEASIQARNT 474
                 78899**********************999999988877777776665 PP

>> Limkain-b1  Limkain b1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0       0.2     3e+02       5      69 ..     140     206 ..     137     228 .. 0.60
   2 ?    4.3   0.1     0.028        43      45      83 ..     275     313 ..     266     318 .. 0.80
   3 ?    6.5   0.1    0.0056       8.4      35      76 ..     414     455 ..     408     466 .. 0.81

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.2
  Limkain-b1   5 lvvsnLPtnrdklkkaiknrLrrLsdncGGkvls.isgks...avlrfanqeaaeralkrleneDvfGn 69 
                 ++++nL t  d  +ka+++ +  + +    kv +  +g+s     ++++  eaa+ a+k +++     +
  EEA21673.1 140 VFIKNLDTAID--NKALHDTFAAFGNILSCKVAQdEFGNSkgyGFVHYETAEAANNAIKHVNGMLLNDK 206
                 67777777777..77777777776666677764313444411167888999999999998765433333 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.028
  Limkain-b1  45 vlrfanqeaaeralkrleneDvfGnritvsekprnkevn 83 
                  +++ + e a+ a+  l++ D +G+++ v    +++e +
  EEA21673.1 275 FVNYVDHENAQTAVDDLNDKDFHGQKLYVGRAQKKHERE 313
                 5788899********************998874444433 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.0056
  Limkain-b1  35 kvlsisgksavlrfanqeaaeralkrleneDvfGnritvsek 76 
                 kv + s++   + f++++ a++a+  +++  v G+ + v   
  EEA21673.1 414 KVFGKSKGFGFVCFSSPDEASKAVTEMNQRMVNGKPLYVALA 455
                 666777777899*****************9999988777655 PP

>> RRM_occluded  Occluded RNA-recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.0     0.015        22       8      74 ..     237     307 ..     232     309 .. 0.87
   2 ?    5.1   0.0     0.014        21       6      41 ..     338     372 ..     335     380 .. 0.90
   3 ?   -2.2   0.0       2.6   3.8e+03      43      69 ..     425     451 ..     421     457 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.015
  RRM_occluded   8 plsDtvnkariralveekegeikkivLvpdheG.....AivefkdekiagkasLaLdgsefegkklrcGtvk 74 
                   ++   v++++ r+l+ +  g+i+   +  d +G      +v + d++ a  a+  L+ ++f+g+kl +G  +
    EEA21673.1 237 NIDPEVTDEEFRELFGKF-GDITSATISRDDSGksrgfGFVNYVDHENAQTAVDDLNDKDFHGQKLYVGRAQ 307
                   777789999999999999.999999999999885555568****************************9875 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.014
  RRM_occluded   6 llplsDtvnkariralveekegeikkivLvpdheGA 41 
                   + +l+D v ++++r+l++   g i+   ++ d  GA
    EEA21673.1 338 VKNLTDDVDDEKLRELFSAF-GTITSAKVMRDTVGA 372
                   669*****************.***999999998888 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 2.6
  RRM_occluded  43 vefkdekiagkasLaLdgsefegkklr 69 
                   v f++   a ka+ +++    +gk l 
    EEA21673.1 425 VCFSSPDEASKAVTEMNQRMVNGKPLY 451
                   78999999*****99999999998875 PP

>> OB_RNB  Ribonuclease B OB domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0      0.01        15       5      18 ..     175     189 ..     174     225 .. 0.83
   2 ?    1.8   0.1      0.13   1.9e+02       5      14 ..     268     277 ..     267     285 .. 0.83
   3 ?    3.0   0.1     0.056        83       3      13 ..     415     425 ..     414     437 .. 0.78

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.01
                 E-SSS-EEEEECT.. CS
      OB_RNB   5 ahkkGFGFlipde.g 18 
                 +++kG+GF+  ++ +
  EEA21673.1 175 GNSKGYGFVHYETaE 189
                 689******999854 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.13
                 E-SSS-EEEE CS
      OB_RNB   5 ahkkGFGFli 14 
                 + ++GFGF+ 
  EEA21673.1 268 GKSRGFGFVN 277
                 6789****96 PP

  == domain 3  score: 3.0 bits;  conditional E-value: 0.056
                 EEE-SSS-EEE CS
      OB_RNB   3 vrahkkGFGFl 13 
                 v + +kGFGF+
  EEA21673.1 415 VFGKSKGFGFV 425
                 56889*****9 PP

>> CSD  'Cold-shock' DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.1     0.042        63       8      22 ..     174     188 ..     172     192 .. 0.83
   2 ?    2.2   0.1      0.11   1.7e+02      11      23 ..     270     282 ..     268     296 .. 0.87
   3 ?    3.1   0.1     0.056        83       6      20 ..     414     428 ..     413     434 .. 0.83

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.042
                 EETTTTEEEEEETTS CS
         CSD   8 fnakkgfGFItredg 22 
                 f ++kg+GF+ +e  
  EEA21673.1 174 FGNSKGYGFVHYETA 188
                 7789******99865 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.11
                 TTTEEEEEETTSS CS
         CSD  11 kkgfGFItredgd 23 
                 ++gfGF+++ d++
  EEA21673.1 270 SRGFGFVNYVDHE 282
                 68******99986 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.056
                 EEEETTTTEEEEEET CS
         CSD   6 kwfnakkgfGFItre 20 
                 k f ++kgfGF+  +
  EEA21673.1 414 KVFGKSKGFGFVCFS 428
                 78999******9755 PP

>> DUF4834  Domain of unknown function (DUF4834)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.1       5.6   8.3e+03      59      59 ..     304     304 ..     247     340 .. 0.55
   2 ?   11.3   1.4   0.00034       0.5      18      90 ..     358     421 ..     351     426 .. 0.52

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 5.6
     DUF4834  59 s 59 
                  
  EEA21673.1 304 G 304
                 1 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00034
     DUF4834  18 glsilsvilrtvfglgsrkkssksaqkqfgnstnsnqqksqsrsetkeegeiieeersekeakrkkiFekdeG 90 
                 g +  ++++r   g+gs +++  +++k+++++ +++++       ++++ ++++e+++  ++++kk+F k++G
  EEA21673.1 358 GTITSAKVMRDTVGAGSDSEK--EETKESSEEVEEPKE-------EETNAKTEDEDKTDAKKSDKKVFGKSKG 421
                 555556677777776643332..233333333333322.......2222233333333333566899999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (748 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1488  (0.082994); expected 358.6 (0.02)
Passed bias filter:                      650  (0.0362541); expected 358.6 (0.02)
Passed Vit filter:                        78  (0.00435049); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.79u 0.27s 00:00:01.06 Elapsed: 00:00:00.44
# Mc/sec: 5124.07
//
Query:       EEA21674.1  [L=412]
Description: FAD dependent oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.5e-64  216.2   0.2    1.1e-63  216.0   0.2    1.0  1  DAO            FAD dependent oxidoreductase
    1.7e-05   25.0   0.2      4e-05   23.7   0.2    1.7  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
     0.0011   18.1   0.0     0.0018   17.4   0.0    1.2  1  FAD_binding_2  FAD binding domain
     0.0093   15.2   0.0      0.058   12.6   0.0    2.0  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
       0.01   15.2   0.0      0.014   14.7   0.0    1.2  1  FAD_oxidored   FAD dependent oxidoreductase
      0.044   14.3   0.1       0.36   11.4   0.1    2.2  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
      0.046   13.0   0.2        0.2   10.8   0.1    1.8  2  FAD_binding_3  FAD binding domain
      0.093   12.9   0.0       0.25   11.5   0.0    1.7  1  HTH_17         Helix-turn-helix domain
       0.13   11.5   0.0       0.21   10.9   0.0    1.3  1  AlaDh_PNT_C    Alanine dehydrogenase/PNT, C-terminal domain
       0.16   11.2   0.0       0.33   10.2   0.0    1.4  1  Thi4           Thi4 family
       0.17   11.1   0.7       0.34   10.1   0.3    1.6  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase


Domain annotation for each model (and alignments):
>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  216.0   0.2   6.6e-67   1.1e-63       3     349 ..      39     406 ..      37     409 .. 0.84

  Alignments for each domain:
  == domain 1  score: 216.0 bits;  conditional E-value: 6.6e-67
                 EEECTSHHHHHHHHHHHHT.T..EEEEESSSSTTSSGGGSSEEEEESSSSTHHSTHHHHHHHHHHHHHHHHHHHHHSSTTSEEEEEEEEEESSHHHHHH CS
         DAO   3 viiGGGiiGlstAyeLarr.g..VtllekgdiagsgaSgrnsgllhsglrylpeaselarlslealeelreleeelgididyrrtGllslaadeeelea 98 
                 ++iGGG++Gl++A++La+r g  ++llek+d +g+++S+rns ++h+g++y+++   + rl+  + + l+++++e    i++r+t + ++a+++ e++a
  EEA21674.1  39 AVIGGGVVGLAIARQLAAReGtsTILLEKHDAVGTETSSRNSEVIHAGIYYPADS-LKTRLCISGKNKLYAYCAEKQ--IPHRNTKKWVVAQNDVEWQA 134
                 7***************988579***************************966655.888***************965..99***********9999999 PP

                 HHHHHHHHHHTTTTEEEEEHHHHHHHSTTSTTTSEEEE.ETTEEEEEHHHHHHHHHHHHHHTT-EEEESECEEEEEEEE..TCEEEEE....EECTEEE CS
         DAO  99 ldkllallleagldaelldaeevrelepalpgllgalf.ypdtgqvdpakltaalaraaealGveilegtevtgleeed..gkvwgve....rttpgen 190
                 + +  + +++ g++++++++ee++++ep + +  ++++ +p+tg+vd + l+a+l  ++e+lG++i ++tevt++e  d  +++++++         en
  EEA21674.1 135 CLNVHEHAQKIGVPTRFVSQEEAARIEPDV-RAEAGIVeSPTTGIVDVHSLMASLEGDFENLGGDIAFQTEVTRIEPIDsgKGGYEIFasspG----EN 228
                 85555556999*****************64.55677666************************************886655555666676652....33 PP

                 .E....EEEEEEE--GGGHHHH.HTT.CTT..TSEEEEEEEEEEEEEECCTHSTGSGCSEEEEEEEETTTTEEEEEETTSEEEEEESSEEETTCSSTSC CS
         DAO 191 .d....aadavVnaaGawsdll.gll.kel..dlpispvrgqvlvlkplseklvspaailpvpetdddgrgvyvtprkdgrvlvGgtadeesgdddpev 280
                  +    +a++++n+aG+++  + +++ ++   ++p   ++g+++ +   s++   + +i+p p++ ++g g+++t + ++r+++G++ +++s+++d ++
  EEA21674.1 229 gEessiTAETIINSAGLYACHInNMIlPPSrhRQP-FYAKGTYFSY-GASRPK-PSTLIYPAPVPGHGGLGTHLTLDMGNRIRFGPDVEWTSDPTDYKP 324
                 3233445577*********9998888866633455.557*******.444422.2359*****************************9988888888** PP

                 SHHHHHHHHHHHHHHSGGG..CGEEEEEEEEEE.ETTS..........SEEEEEEETEEEEEEEEECTTTHHHHHHHHHHHH CS
         DAO 281 deedidellealrklfPql..gdvlrkwaGlrp.lpdg..........lpligetpgvkglylatGhsghGltlapatGkll 349
                 +++++++ l+++r+++P++  + ++  ++G+rp l  g          +++i ++ g++g++ + G++++Glt+++a+G+++
  EEA21674.1 325 SPARLEQALPEIRRYLPAIdvDAIEIDYCGIRPkLGQGsantagkgfqDFVIVKEDGFEGFVNLLGIESPGLTSSLAIGEMV 406
                 ******************54344777*******633333455778999999998779**********************987 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.7   0.2   2.5e-08     4e-05       1      40 [.      40      80 ..      40      97 .. 0.87

  Alignments for each domain:
  == domain 1  score: 23.7 bits;  conditional E-value: 2.5e-08
                   EE--SHHHHHHHHHHHCC.TEEEEEE-SSSSSSGGG-EECE CS
  NAD_binding_8  1 IvGaGlsGlvaAylLaka.gfdvlllekrdrlGGraasyev 40
                   ++G+G+ Gl++A+ La + g +  llek+d +G   +s++ 
     EEA21674.1 40 VIGGGVVGLAIARQLAAReGTSTILLEKHDAVGTETSSRNS 80
                   8*************99866**************99998865 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.0   1.1e-06    0.0018       4     200 ..      40     244 ..      38     269 .. 0.79

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 1.1e-06
                    EE--SHHHHHHHHHHHH.TTT-EEEEESSSGGGS.....GGGG--S-EE-TT..SSGGSTC.CHHHHHHHHHHHHTTT-S-HHHHHHHHHTHHHHH CS
  FAD_binding_2   4 ViGsGlAGLaAAleaae.aGlkvavvekeqefgg.....atawsqGgidavlspeqkkagikdspelhrtdtlkaldeladqplveafveaapeav 93 
                    ViG+G+ GLa A ++a  +G +++++ek +++g      ++    +gi  ++ + + ++ i  + +l ++ + k+ ++++ +++v a  +   +a 
     EEA21674.1  40 VIGGGVVGLAIARQLAArEGTSTILLEKHDAVGTetssrNSEVIHAGIYYPADSLKTRLCISGKNKLYAYCAEKQIPHRNTKKWVVAQNDVEWQAC 135
                    9************99874777**********99987555555668999999999999999999999999999999999999999999999555555 PP

                    HHHHHT....T----BCCTSSB-EEE-TT-SSTEEEE-.STT-......HHHHHHHHHHHHHHTCTEEEEESEEEEEEEECTTEEEEEEEEET... CS
  FAD_binding_2  94 deLeel....gvpfsrtedgpvdvrelGglsatartlhdaadarretlvtghallarlvesarkagvdfqerteadeLivedgrvtGavvenp... 182
                       +e+    gvp        v + e     ++ r  ++    + + +v+ h l+a l   ++++g d+ ++te++++   d +  G ++  +   
     EEA21674.1 136 LNVHEHaqkiGVPTRF-----VSQEEAARIEPDVRAEAGIVESPTTGIVDVHSLMASLEGDFENLGGDIAFQTEVTRIEPIDSGKGGYEIFASspg 226
                    5555555878888877.....777777788888777786666655999999999999999999999999999999999775665555555444457 PP

                    TTTCEEEEEESEEEE--- CS
  FAD_binding_2 183 esgrevrirakavvlatg 200
                    e+g+e  i+a  ++  +g
     EEA21674.1 227 ENGEESSITAETIINSAG 244
                    888888877776666555 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.0   3.5e-05     0.058     144     187 ..      37      81 ..       7      87 .. 0.67
   2 ?   -0.4   0.0      0.34   5.5e+02     189     237 ..     188     245 ..     179     250 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 3.5e-05
                  EEEEES-SHHHHHHHHHHHHH.T-EEEEEESSSSSSTTS-HHHHH CS
                  xxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 144 rivvvGgGyiGvElAaalakl.gkevtlveardrllraldkelsa 187
                    +v+GgG++G+ +A +la   g  + l+e  d +  ++ ++ s+
   EEA21674.1  37 THAVIGGGVVGLAIARQLAAReGTSTILLEKHDAVGTETSSRNSE 81 
                  348999999999999997766588888888888887666555555 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.34
                  HHHHHHHTTEEEEESCEEEEEEETTE......EEE....EEETTSCEEEESEEEE-S-E CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxx......xxx....xxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 189 leealekeGvevklgtsvkeidgnge......kle....vvledgeeidadlvvvavGv 237
                  le  +e+ G ++ ++t+v++i++ ++              +++++++i a++++ ++G+
   EEA21674.1 188 LEGDFENLGGDIAFQTEVTRIEPIDSgkggyeI-FasspGENGEESSITAETIINSAGL 245
                  667788888899999999999998888886640.2333466666666999999999986 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   0.0   8.8e-06     0.014       4      41 ..      40      78 ..      39     144 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 8.8e-06
  FAD_oxidored  4 VvGGgpaGvaAAia.AaraGakvlLveergvlGGlltsg 41
                  V+GGg+ G+a A + Aar+G +++L+e+++ +G  ++s 
    EEA21674.1 40 VIGGGVVGLAIARQlAAREGTSTILLEKHDAVGTETSSR 78
                  9********9998779****************9777765 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1   0.00022      0.36       3      35 ..      39      72 ..      37      81 .. 0.84
   2 ?   -0.2   0.0      0.92   1.5e+03      46      72 ..     188     214 ..     182     219 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00022
                EEECSSHHHHHHHHHHHH.TTSEEEEEESSSSSS CS
   Pyr_redox  3 vvvGgGyiglElAgalae.lgkkVtvversdkll 35
                +v+GgG++gl  A  la+  g ++ ++e +d + 
  EEA21674.1 39 AVIGGGVVGLAIARQLAArEGTSTILLEKHDAVG 72
                7***************764788999999888776 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.92
                 HHHHHHHTTEEEECSEEEEEEEEETTS CS
   Pyr_redox  46 lqeklekngievllntkveeiegsedg 72 
                 l+  +e++g ++ ++t+v++ie  ++g
  EEA21674.1 188 LEGDFENLGGDIAFQTEVTRIEPIDSG 214
                 56678999999**********977765 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.1   0.00013       0.2       5      35 ..      39      70 ..      35      85 .. 0.85
   2 ?   -0.4   0.0      0.32   5.1e+02      84     135 ..     162     212 ..     116     245 .. 0.63

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00013
                   EEE--SHHHHHHHHHHH.HTTHHEEEEESSSS CS
  FAD_binding_3  5 lIVGaGpaGlmlallLs.eaGvrvvlvekrst 35
                   +++G+G +Gl  a+ L+ + G +++l+ek++ 
     EEA21674.1 39 AVIGGGVVGLAIARQLAaREGTSTILLEKHDA 70
                   69***********9996378*********985 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.32
                    CEEEEEHHCHHCST-CEE--HHHHHHHHHHHHHHHTEEETCSEEEECCEECC CS
  FAD_binding_3  84 pkaradlelesspervtvypqteleriLvehaeerglqvrfktevesleqde 135
                    p++ra+     + +++ ++ ++ l   L+ + e+ g ++ f+tev+ +e  +
     EEA21674.1 162 PDVRAEAG-IVESPTTGIVDVHSLMASLEGDFENLGGDIAFQTEVTRIEPID 212
                    55555555.3344455667778888888888999999999999988666444 PP

>> HTH_17  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   0.00016      0.25      14      44 ..     102     131 ..      98     131 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00016
      HTH_17  14 srstvyrlirrgelpaakiGrrwriprsdle 44 
                 +++++y ++ ++++p+ +  ++w + ++d+e
  EEA21674.1 102 GKNKLYAYCAEKQIPHRNT-KKWVVAQNDVE 131
                 589***********77744.55*******97 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00013      0.21      32      77 ..      39      85 ..      21     144 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00013
                 EEESTSHHHHH.HHHHHHHTT-EEEEEESSHHHHHHHHHTTTCECEE CS
  AlaDh_PNT_C 32 lviGgGvaGlq.AiatakglgakVtvlDvrparleqleslgakfvev 77
                  viGgGv+Gl+ A + a++ g ++ +l++  a+  + +s +++++++
   EEA21674.1 39 AVIGGGVVGLAiARQLAAREGTSTILLEKHDAVGTETSSRNSEVIHA 85
                 69********845578999***********99999999988887776 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0    0.0002      0.33      21      55 ..      39      73 ..      23      83 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.0002
                EEE--SHHHHHHHHHHHHCTTS-EEEEESSSS--T CS
        Thi4 21 vivGaGssGLtaayylakkpdlkvailersvspGG 55
                +++G+G  GL+ a+ la + +  +++le++ ++G 
  EEA21674.1 39 AVIGGGVVGLAIARQLAAREGTSTILLEKHDAVGT 73
                699****************9*********999985 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.3   0.00021      0.34       2      33 ..      40      71 ..      39      77 .. 0.88
   2 ?   -2.6   0.0       1.6   2.6e+03     100     135 ..     201     246 ..     198     254 .. 0.56

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00021
  Pyr_redox_3  2 IiGaGPaGlaaaielkkagledylilEkgnig 33
                 +iG+G  Gla+a +l   + ++ + lEk+ ++
   EEA21674.1 40 VIGGGVVGLAIARQLAAREGTSTILLEKHDAV 71
                 8***************999999******9554 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.6
  Pyr_redox_3 100 lfeeVesvkk...edegfevetsk..e.....tyeAkkviiAtGef 135
                   ++eV+++++    ++g+e+ +s+  e     +++A+++i ++G +
   EEA21674.1 201 FQTEVTRIEPidsGKGGYEIFASSpgEngeesSITAETIINSAGLY 246
                  5566666655322345566655432202223378888888888877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (412 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       485  (0.0270511); expected 358.6 (0.02)
Passed bias filter:                      452  (0.0252106); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 2897.97
//
Query:       EEA21675.1  [L=918]
Description: C2H2 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.3e-13   47.8   0.5    2.6e-12   46.4   0.5    1.7  1  Fungal_trans  Fungal specific transcription factor domain
    1.9e-06   28.0  14.4     0.0081   16.6   2.1    3.0  2  zf-C2H2       Zinc finger, C2H2 type
    3.4e-06   27.2   8.8    3.4e-06   27.2   8.8    3.7  4  zf-H2C2_2     Zinc-finger double domain
    3.6e-05   24.2  11.9      0.022   15.6   1.3    3.0  2  zf-C2H2_4     C2H2-type zinc finger
     0.0001   22.5  12.1      0.024   14.9   4.2    3.3  3  zf-C2H2_jaz   Zinc-finger double-stranded RNA-binding
    0.00024   21.4  12.1      0.033   14.6   1.5    3.0  3  zf-met        Zinc-finger of C2H2 type
  ------ inclusion threshold ------
      0.039   13.1   0.3      0.062   12.5   0.3    1.2  1  EutH          Ethanolamine utilisation protein, EutH
      0.051   13.5   7.1       0.24   11.3   1.6    2.5  2  zf-C2HC_2     zinc-finger of a C2HC-type
       0.15   10.2  11.9        0.3    9.2  11.9    1.4  1  SSP160        Special lobe-specific silk protein SSP160
       0.21   11.7   1.3       0.68   10.1   1.3    1.8  1  PHD_4         PHD-finger
       0.47   10.5   7.2       0.12   12.4   1.1    2.5  2  zf-C2H2_6     C2H2-type zinc finger
        3.5    5.5   3.5        4.7    5.0   3.5    1.1  1  Dicty_REP     Dictyostelium (Slime Mold) REP protein
        4.2    7.7   7.0        7.7    6.8   3.7    2.5  2  C1_4          TFIIH C1-like domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.4   0.5   1.9e-15   2.6e-12       1     201 [.     418     618 ..     418     634 .. 0.77

  Alignments for each domain:
  == domain 1  score: 46.4 bits;  conditional E-value: 1.9e-15
  Fungal_trans   1 ldrffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltses.qefiafplraeilihedfsspssslwilq. 95 
                   ld++f +fhp+ p++h p+f  k+          +++ ll++++++G+  +++   +s  s+t     e i + l++      ++  + +s+ ++  
    EEA21675.1 418 LDLYFRHFHPLVPFVHLPTFCAKK----------TKTPLLFVMCQIGMIILGTKGTTSFVSKTFTCsLERISSELAK------CAIGNETSTGVVSt 498
                   799*********************..........*******************999997666653244455333333......55556666777777 PP

  Fungal_trans  96 ...sLlllelyektssd..ralher.hhgvavrlarslgLhrnpsyvgkks...........lwklweeeaesrrRlwwaaFylDktialklGrppl 175
                      +Ll+l+l  +t ++  + +  + +++++ ++a++ gL    +  + +             wk w    es +Rl  +   lD ++++ l   p+
    EEA21675.1 499 faaALLMLNLAALTGEKshIQQSQMlYINLM-SIAQRHGLFTAGEGQSVDMslfeavpdlemRWKAWSR-VESTKRLIVGLLLLDSWFSSFLSTSPI 593
                   7668888888877777323444444655555.555555554333333333458899***999*******.*************************** PP

  Fungal_trans 176 lddsqinlpLPcddddlwesddasee 201
                   +  +++++ LPc ++ l ++++ s +
    EEA21675.1 594 IAPDSVQIVLPCHES-LFQANSSSRW 618
                   ***************.8888887766 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   4.7   9.1e-06     0.013       2      23 .]       5      26 ..       5      26 .. 0.98
   2 !   16.6   2.1   5.8e-06    0.0081       1      23 []      32      54 ..      32      54 .. 0.97

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 9.1e-06
                EETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2  2 kCpdCgksFkrksnLkrHirtH 23
                kC++C+++Fk  +++krH r+H
  EEA21675.1  5 KCEICDRKFKKTEHYKRHERSH 26
                7********************9 PP

  == domain 2  score: 16.6 bits;  conditional E-value: 5.8e-06
                EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCpdCgksFkrksnLkrHirtH 23
                y+C++C+k+F+r++ L rH + H
  EEA21675.1 32 YECTVCHKKFSRSDVLSRHAKGH 54
                99*****************9988 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.9      0.15   2.1e+02      16      26 .]       5      15 ..       4      15 .. 0.92
   2 !   27.2   8.8   2.5e-09   3.4e-06       1      25 [.      18      42 ..      18      43 .. 0.95
   3 ?   -1.8   0.0       3.7     5e+03       2      10 ..      47      55 ..      47      59 .. 0.87
   4 ?   -1.7   0.5       3.5   4.8e+03      19      26 .]     437     444 ..     435     444 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.15
   zf-H2C2_2 16 eCplCdkaFkt 26
                +C+ Cd +Fk+
  EEA21675.1  5 KCEICDRKFKK 15
                7********96 PP

  == domain 2  score: 27.2 bits;  conditional E-value: 2.5e-09
   zf-H2C2_2  1 nLrrHirkHtgekpyeCplCdkaFk 25
                +++rH r+Ht+e+pyeC +C+k+F+
  EEA21675.1 18 HYKRHERSHTKERPYECTVCHKKFS 42
                699*********************8 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 3.7
   zf-H2C2_2  2 LrrHirkHt 10
                L+rH + H 
  EEA21675.1 47 LSRHAKGHI 55
                89****996 PP

  == domain 4  score: -1.7 bits;  conditional E-value: 3.5
   zf-H2C2_2  19 lCdkaFkt 26 
                 +C+k++kt
  EEA21675.1 437 FCAKKTKT 444
                 8****997 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   3.5   0.00013      0.18       2      23 ..       5      26 ..       4      27 .. 0.95
   2 !   15.6   1.3   1.6e-05     0.022       1      23 [.      32      54 ..      32      55 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 0.00013
   zf-C2H2_4  2 kCpiCgksFsskkaLlrHlkth 23
                kC+iC++ F+  ++++rH ++h
  EEA21675.1  5 KCEICDRKFKKTEHYKRHERSH 26
                8*******************99 PP

  == domain 2  score: 15.6 bits;  conditional E-value: 1.6e-05
   zf-C2H2_4  1 fkCpiCgksFsskkaLlrHlkth 23
                ++C++C+k Fs+++ L+rH k h
  EEA21675.1 32 YECTVCHKKFSRSDVLSRHAKGH 54
                89********99999****9988 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   4.2   1.7e-05     0.024       3      24 ..       5      26 ..       4      28 .. 0.95
   2 !   10.7   0.3   0.00038      0.52       2      24 ..      32      54 ..      31      55 .. 0.90
   3 ?    0.1   0.0      0.79   1.1e+03      12      23 ..     613     624 ..     611     627 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.7e-05
                 BBTTTTBBBSSHHHHHCCTTSH CS
  zf-C2H2_jaz  3 YCvlCdKyFksenaldnHlkSK 24
                  C++Cd+ Fk+ + ++ H++S+
   EEA21675.1  5 KCEICDRKFKKTEHYKRHERSH 26
                 5********************6 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 0.00038
                 CBBTTTTBBBSSHHHHHCCTTSH CS
  zf-C2H2_jaz  2 fYCvlCdKyFksenaldnHlkSK 24
                 ++C +C K F+ + +l  H k++
   EEA21675.1 32 YECTVCHKKFSRSDVLSRHAKGH 54
                 89****************97775 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.79
                  SSHHHHHCCTTS CS
  zf-C2H2_jaz  12 ksenaldnHlkS 23 
                  +s++ + +H+++
   EEA21675.1 613 NSSSRWMQHIRG 624
                  78899*****99 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   1.5   2.4e-05     0.033       3      23 ..       6      26 ..       4      27 .. 0.94
   2 !   13.2   0.8   6.4e-05     0.089       1      23 [.      32      54 ..      32      55 .. 0.95
   3 ?   -1.6   0.1         3   4.2e+03      11      24 ..     613     626 ..     611     626 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 2.4e-05
      zf-met  3 CelCnvtfnsesqlksHlqGK 23
                Ce+C+++f+   ++k H +++
  EEA21675.1  6 CEICDRKFKKTEHYKRHERSH 26
                *******************98 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 6.4e-05
      zf-met  1 fyCelCnvtfnsesqlksHlqGK 23
                ++C +C+++f+   +l  H +G+
  EEA21675.1 32 YECTVCHKKFSRSDVLSRHAKGH 54
                79*****************9996 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 3
      zf-met  11 nsesqlksHlqGKk 24 
                 ns s + +H +G k
  EEA21675.1 613 NSSSRWMQHIRGGK 626
                 7888899****965 PP

>> EutH  Ethanolamine utilisation protein, EutH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.3   4.5e-05     0.062     233     301 ..     446     517 ..     416     540 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 4.5e-05
        EutH 233 aleivgsiaivlaGafplvalitkvlkkpleklgkkl...ginevaaaGllaslannipmfallkdmdergk 301
                  l ++++i+++++G+   +++++k+++  le++++ l    i ++  +G++ ++a  + m++l     e++ 
  EEA21675.1 446 LLFVMCQIGMIILGTKGTTSFVSKTFTCSLERISSELakcAIGNETSTGVVSTFAAALLMLNLAALTGEKSH 517
                 67899*****************************865222799999***************99776666655 PP

>> zf-C2HC_2  zinc-finger of a C2HC-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   1.6   0.00018      0.24       2      22 ..       3      24 ..       2      25 .. 0.88
   2 ?    4.8   0.3      0.02        27       4      22 ..      33      52 ..      32      52 .. 0.93

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00018
   zf-C2HC_2  2 lvpCpkCgRsF.npdrlekHep 22
                l++C++C R+F +++   +He+
  EEA21675.1  3 LRKCEICDRKFkKTEHYKRHER 24
                799********88888888886 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.02
   zf-C2HC_2  4 pCpkCgRsF.npdrlekHep 22
                +C  C  +F  +d l +H +
  EEA21675.1 33 ECTVCHKKFsRSDVLSRHAK 52
                6*****************75 PP

>> SSP160  Special lobe-specific silk protein SSP160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2  11.9   0.00022       0.3     661     700 ..      52      90 ..      30     104 .. 0.69

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00022
      SSP160 661 eaayqncvdpgsvpdeattttssttttttttttaaptttt 700
                 +   qn   p  + ++a+ tt++tttttttttt  ptt++
  EEA21675.1  52 KGHIQNANGPTNIANAAKNTTATTTTTTTTTTT-PPTTAA 90 
                 556799*******99998888777666655554.565543 PP

>> PHD_4  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   1.3   0.00049      0.68       6      52 ..       5      53 ..       2      63 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00049
       PHD_4  6 aCivCgedgkedevv..eeesetpsslmeCsvCyeivHpeClkekegeg 52
                 C +C ++ k+ e    +e+s+t++   eC+vC++   ++ + +++++g
  EEA21675.1  5 KCEICDRKFKKTEHYkrHERSHTKERPYECTVCHKKFSRSDVLSRHAKG 53
                7****9987777655566779999*********9988877776666666 PP

>> zf-C2H2_6  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.6      0.41   5.7e+02       3      12 ..       5      14 ..       3      25 .. 0.88
   2 ?   12.4   1.1   8.6e-05      0.12       2      22 ..      32      52 ..      32      55 .. 0.87

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.41
   zf-C2H2_6  3 eCsvCsksFp 12
                +C +C++ F+
  EEA21675.1  5 KCEICDRKFK 14
                8*****9997 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 8.6e-05
   zf-C2H2_6  2 heCsvCsksFpslqaLggHkk 22
                +eC+vC+k F+  + L  H k
  EEA21675.1 32 YECTVCHKKFSRSDVLSRHAK 52
                9**********9999988866 PP

>> Dicty_REP  Dictyostelium (Slime Mold) REP protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   3.5    0.0034       4.7     251     280 ..      66      95 ..      42     156 .. 0.67

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0034
   Dicty_REP 251 keknkttttttttttttsqartrkrkaidd 280
                 +  ++tt ttttttttt+++ t+   a+++
  EEA21675.1  66 NAAKNTTATTTTTTTTTTTPPTTAADAVGP 95 
                 333455555566666666666666555554 PP

>> C1_4  TFIIH C1-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   3.7    0.0056       7.7       2      35 ..       6      41 ..       5      45 .. 0.84
   2 ?    0.9   0.1      0.39   5.4e+02       5      38 ..     695     728 ..     693     738 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0056
        C1_4  2 CygCqkkfpklakkkkdee..ltssryrCekCkndF 35
                C  C +kf+k+++ k +e+  + +  y+C  C+++F
  EEA21675.1  6 CEICDRKFKKTEHYKRHERshTKERPYECTVCHKKF 41
                999*******9999887765456677********99 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.39
        C1_4   5 CqkkfpklakkkkdeeltssryrCekCkndFCiD 38 
                 C+++++ +  ++ +e+l+ +  +C    ++ C+D
  EEA21675.1 695 CLTSLQVQLMNTYSESLSRMNPNCIVMWHHMCMD 728
                 9999999999999999****************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (918 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       726  (0.0404931); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        71  (0.00396006); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.77u 0.33s 00:00:01.10 Elapsed: 00:00:00.50
# Mc/sec: 5509.89
//
Query:       EEA21676.1  [L=621]
Description: homogentisate 1,2-dioxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.2e-136  455.0   0.0   2.6e-136  454.7   0.0    1.1  1  HgmA      homogentisate 1,2-dioxygenase


Domain annotation for each model (and alignments):
>> HgmA  homogentisate 1,2-dioxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  454.7   0.0  1.5e-140  2.6e-136       1     406 [.      40     454 ..      40     477 .. 0.92

  Alignments for each domain:
  == domain 1  score: 454.7 bits;  conditional E-value: 1.5e-140
                 -EEE-TT--EEETTSTT-S-SS-S--SS-GGG-EEEEEESS-TTS-GGG--EEEEEESS-TT-S---EE--..-TB----CCCS--....--S-EEE-S CS
        HgmA   1 kylsGfgnefesealkgalPegqnsPqkapyglyaeqlsGtaftaprsenkrsWlyrirPsvahepfekleeaeeklvaelkeeas....apnqlrWkP 95 
                 +y++G+gn+f+se ++g+lP gqn+Pq++ +gly+e ++ +af+apr+ n  +++yr+rP++ah+++++  e++ ++ + + + ++      +q  W P
  EEA21676.1  40 EYQAGWGNRFQSEVIPGTLPAGQNNPQEVRFGLYTEGITYSAFAAPRHANFSTYMYRVRPAAAHNGYKTNIETKAHIENCFLSINPkvetLSEQAEWAP 138
                 6******************************************************************99888887777666554442222568999*** PP

                 ----.TT----TTTTEEEEEEECECCCTEEEEEEEEEE-S---SEEEEESSEEEEEEEEES-EEEEETTEEEEE-TTEEEEE-TT--EEEE-S...SSE CS
        HgmA  96 lelp.seekvdfveglltlagagdalsrtGlaihlylanksmedkafynadGellivpqkGelelvtelGrlkvepgeiaviprGvrfkvele..deea 191
                 ++lp + e++dfv+gl+tl g+gd++ r+G+a++++++n+sm+++af+n dG++l+v+q+G+l+++te+G++ ++pgei+vi+rGvrf++ l   ++ea
  EEA21676.1 139 FPLPaETETIDFVDGLHTLGGSGDPNLREGIALYVFMINASMDHRAFCNLDGDFLLVAQHGNLDIQTEFGKIFLQPGEICVIQRGVRFSIRLGpgHKEA 237
                 ****666889*********************************************************************************9633578* PP

                 EEEEEEEES--EE----GGGTTS-BS-GGGEEEE-------EEEEEEEEEEETTEEEEEEEEE-S--EEEEEES---EEEEGGG-B----SSSS---GG CS
        HgmA 192 rGyilevygakfklPdlGPiGanglanprdfkaPvaayedkeskeltviskfqgklfaakldhspldvvaWhGnyvPykydlkkfnvinsvsfdhpdPs 290
                 rGyi+e +g+ ++lPdlGP+G  glanprdf +Pva  +d+ ++  t+++k +gk+ + ++dh+p+d+vaWhGn vPykydl+kf++ ns s+dh+dPs
  EEA21676.1 238 RGYITEIWGSIWELPDLGPLGGHGLANPRDFLYPVACIDDNLHESWTIVNKSNGKYNSLSQDHTPYDLVAWHGNVVPYKYDLTKFSSQNSTSIDHTDPS 336
                 *************************************************************************************************** PP

                 GGEEEEEE-SSTT-EEEEEEEE-SEEE--TTS--S---B--SSEEEEEEEE-----------TT-EEEE-TT--B---HHHHHHHHH.S----EEEST. CS
        HgmA 291 iftvltapsekeGvaivdfvifpPrWlvaektfrPPyyhrnvmsefmGlieGaydakeeGfvpgGaslhslmtahGPdaesfekask.aelkPekidd. 387
                 ++ vlta+s+ + ++ vdf+ f PrW va +tfr Py+hrn  +ef+  ++G+   +++ f+pgG+s+    t+hG  +e+++  ++ +e +P++i + 
  EEA21676.1 337 VNCVLTAKSRDPNTSLVDFLWFGPRWDVASNTFRLPYFHRNSATEFLASLYGNGLGRSDDFLPGGGSVEVSHTPHGGFSEGYQFEMRvQENEPRRILEn 435
                 *********************************************************************************99865526789***9877 PP

                 -EEEEEEESS--EE-HHHH CS
        HgmA 388 tlafmfesslvlavtelaa 406
                  ++ m ess ++  te+a+
  EEA21676.1 436 QMTIMVESSRSFLFTEYAR 454
                 9***************994 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (621 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       460  (0.0256568); expected 358.6 (0.02)
Passed bias filter:                      330  (0.0184059); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.30s 00:00:00.90 Elapsed: 00:00:00.47
# Mc/sec: 3938.60
//
Query:       EEA21677.1  [L=503]
Description: adenylosuccinate lyase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.5e-48  165.1   0.0    5.4e-48  164.0   0.0    1.5  1  Lyase_1   Lyase
      1e-21   77.3   0.0    4.9e-20   71.9   0.0    2.8  2  ADSL_C    Adenylosuccinate lyase C-terminus
     0.0049   17.0   0.0      0.014   15.5   0.0    1.8  1  ASL_C     Adenylosuccinate lyase C-terminal


Domain annotation for each model (and alignments):
>> Lyase_1  Lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  164.0   0.0     9e-52   5.4e-48       8     305 ..      70     349 ..      66     354 .. 0.85

  Alignments for each domain:
  == domain 1  score: 164.0 bits;  conditional E-value: 9e-52
                 CHHHHHHHHHHHHHGGGHHHHHCHHHHHHHHHHHTTSSTHHHHHHHHHHHHHHHCHCHHCGGHHHBSSSSSHHHHHHHHHHHHHHHHTTHSSGIIIIIT CS
     Lyase_1   8 dklmgiftersrenfrlseedikalaalkkaaakanvdlkeeaaaiikaldevleegklddqfvlkviqegsgtavnmnlnevigellgekvepndkvh 106
                 +++++if+++s+ +  ++     a+ al++a  k nv++ ++ a++ + +  v+++++     +l   +e  g  +   l   +++l g   e+ ++vh
  EEA21677.1  70 EEIRQIFNDESYIKRCVD-----AETALARAQSKCNVIPSQIGAEVTQNA--VASKLD---LERLRHETEIVGYPILP-LVRQLSALCG--EEAGKYVH 155
                 678999999999999999.....999*************77777776643..444333...44666666655555544.2223333555..5999**** PP

                 TT--HHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHTTT-EEEEEETTEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHTCEETTTTTTTS CS
     Lyase_1 107 tgqSsnDqvpTalrlalkkalsekLlpaleqLidalkekakefkdvvkiGrThlqdAtPvtlgqelsayaealerdrerlkellkrllvellgggtavg 205
                  g++++D++++a  l++k+ l ++++  l++ i++l+e +++++d++++GrThlq+A Pvt+g +++ +   ++r++erl++l++r l+ ++gg++++ 
  EEA21677.1 156 WGATTQDIMDLASVLQMKDGL-AVVERLLRDVIKTLRELSEKYRDTPMAGRTHLQHALPVTFGYKCAVWLSGFQRHLERLQQLKDRALMAQFGGAAGSL 253
                 *********************.99*************************************************************************** PP

                 STTTSCCTHHHHHHHHHHHHHCSTEESSSHHHHHHC-HHHHHHHHHHHHHHHHHHHHHHHHHHHTSTTTSSEEEEGCCTSSC-TTSTTTEBTHHHHHHH CS
     Lyase_1 206 tglnadpefaelvakelakvtglpvkapnsfeavsdrDavvellgalkllatsLskfaeDlrllssgeaglvelslaesepGSSiMPgKvNPvqlEllt 304
                 + l+       +v+k la+  g    +++s++   +rD v+e+   l+ll  s+ k+a D++++ss e+g+v + +      SS+MP+K+NP+++E++ 
  EEA21677.1 254 ASLGDGDD-GLRVRKALAEELG---LTDPSITWHVARDGVAEITNFLALLGGSMGKLALDIIIMSSNELGEVSEPFVPHRGASSTMPQKRNPISSEVIL 348
                 **987664.4555555554444...34455556689********************************************99**************986 PP

                 H CS
     Lyase_1 305 g 305
                  
  EEA21677.1 349 A 349
                 5 PP

>> ADSL_C  Adenylosuccinate lyase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0     0.045   2.7e+02      50      66 ..      69      85 ..      47      95 .. 0.83
   2 !   71.9   0.0   8.2e-24   4.9e-20       1      73 []     420     497 ..     420     497 .. 0.94

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.045
                HCHHHHHT-GGGCCTTH CS
      ADSL_C 50 eeeldalfdpayylgsa 66
                 ee++++f+ ++y++++
  EEA21677.1 69 TEEIRQIFNDESYIKRC 85
                459**********9987 PP

  == domain 2  score: 71.9 bits;  conditional E-value: 8.2e-24
                 TGGGHHHHHHHHHHTH-HHHHHHHHHHHHHHHHHC...HHHHHHT-HHHH.C.HHCHHHHHT-GGGCCTTHHHHHHHH CS
      ADSL_C   1 GlifservllaLvkglgReeAyelVqeaamkawee...llelLaadpevk.k.seeeldalfdpayylgsadeivdrv 73 
                 Gli++e+v++ +++++gR++A+++V+ea++ + e+   ll+ L+  +ev+ k s e+l+ l++p++ylg+a+++vd v
  EEA21677.1 420 GLIVAEAVMMGMAPYVGRQTAHDIVYEACRNSIEQdksLLDCLLLKDEVTsKmSSEKLESLCNPENYLGAAPKMVDDV 497
                 9*************************************999888777888679889*******************986 PP

>> ASL_C  Adenylosuccinate lyase C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   2.3e-06     0.014      24     114 ..     391     486 ..     382     487 .. 0.80

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 2.3e-06
                 HHHHHHHHHHHCCEEE-HHHHHHHHHT-.GGGGHHHHHHHHHHT.T-TTHHHHHHHHHTTS.---HHHHHHHHHCS-S-HHH.HHHHHC-.-CCC- CS
       ASL_C  24 lialksllkglsklevneealaedLden.wevlaEaiqtvlrre.giekpYeklkeltrgk.kitkeslkefieslevseea.keeLkal.tpatY 114
                 + al ++  +ls l vn++++ ++L+++   ++aEa+ + +  + g + +++ + e  r++ +++k+ l+ ++ + ev++++ +e+L++l +p++Y
  EEA21677.1 391 VGALFQTHFALSGLAVNTKQMLDNLHSTrGLIVAEAVMMGMAPYvGRQTAHDIVYEACRNSiEQDKSLLDCLLLKDEVTSKMsSEKLESLcNPENY 486
                 4566777889****************9835689********97659999***********978888888888888887665515788887568888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (503 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       529  (0.0295053); expected 358.6 (0.02)
Passed bias filter:                      488  (0.0272185); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 3236.43
//
Query:       EEA21678.1  [L=405]
Description: 3-ketoacyl-CoA thiolase B, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.9e-73  245.7   0.1    1.1e-72  244.6   0.0    1.5  2  Thiolase_N     Thiolase, N-terminal domain
    1.1e-41  141.3   0.0    2.2e-41  140.3   0.0    1.5  1  Thiolase_C     Thiolase, C-terminal domain
      0.003   17.2   0.0      0.011   15.3   0.0    2.0  1  ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
  ------ inclusion threshold ------
       0.11   12.1   2.2        1.3    8.7   0.0    2.8  3  Prolactin_RP   Prolactin-releasing peptide


Domain annotation for each model (and alignments):
>> Thiolase_N  Thiolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  244.6   0.0   2.3e-76   1.1e-72       1     260 []      17     275 ..      17     275 .. 0.92
   2 ?   -2.5   0.0      0.57   2.5e+03      34      92 ..     339     398 ..     314     400 .. 0.70

  Alignments for each domain:
  == domain 1  score: 244.6 bits;  conditional E-value: 2.3e-76
                 EEEEEEEEE--EE.TTSTTTTS-HHHHHHHHHHHHHHHHTS-GGGCCEEEEEHSSCTTSTSCHHHHHHHHTTS-TTSEEEEEEHGGGHHHHHHHHHHHH CS
  Thiolase_N   1 vvivsaartpigk.fggslkdlsaeeLlaealkallekagvdpeevdevivGnvlqagegqniarqaalkagipeevpavtvnkvcsSglkavalaaqs 98 
                 vv+ sa+r+pi++ f+g +kdl+ ee+l  +++a++++a+++p +v++v +Gnvl++   +   r+a  +ag+p++++++t n++csSgl+a++++  +
  EEA21678.1  17 VVVLSAVRSPITRaFKGGFKDLWPEEILMPVMQAAVQRAKIQPGDVNDVLIGNVLAELGFAKTGRMALNAAGFPNSTTFHTTNRQCSSGLQAITHISHA 115
                 89*******************************************************99999************************************* PP

                 HHTTSHSEEEEEEEEESTTS-EEETCTTTTGGSSSSEEEEEHHHHHHTEETTTTSEHHHHHHHHHHHHT--HHHHHHHHHHHHHHHHHHHHTTTTTTTB CS
  Thiolase_N  99 iaageadvvvagGvEsmsnaptaestdvrsglklgdekakdllipdgladafneehmGltaenlakkykisReeqdefAvkshqkaaaaqkagkFkdei 197
                 i++g++dv + gGvEsm++ +t     v  + +l+++ +kd             + mG t+en+a++y++sR+eqde+A++s+++a+ aqk+g F++ei
  EEA21678.1 116 IMVGQIDVGMGGGVESMTRWYTTRGIPVDVSPTLKNSPIKDARDCI--------MPMGFTSENVAERYGVSRQEQDEYAAESQRRASVAQKSGLFEKEI 206
                 *********************9998877777777776655544222........456****************************************** PP

                 E-EEEEESSSE.E.....EE-S-TTS-TT--HHHHHTS-BSSSTTSS-BTTSB--BEEEEEEEEEEEHH CS
  Thiolase_N 198 vPvkvkgkkgk.k.....tvdkdeairsevtaekLaklkpaFkkeGtvtAgnasqisDGaaavllmses 260
                 +P++    +++ k      ++ de+ir++v+ ekLaklkpaFk++G  tAgn+sqisDGa+ v+l+++s
  EEA21678.1 207 IPINARWIDEEtKeegerLISLDEGIRHGVNYEKLAKLKPAFKENGGSTAGNSSQISDGASSVILARRS 275
                 ***986555443245666***********************************************9875 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.57
                 HHHHHTS-GGGCCEEEEEHSSCTTSTSC.HHHHHHHHTTS-TTSEEEEEEHGGGHHHHHH CS
  Thiolase_N  34 llekagvdpeevdevivGnvlqagegqn.iarqaalkagipeevpavtvnkvcsSglkav 92 
                 +l k g+dp++v+ +  +  l    g++   + a+l a+++++     +  +c+S   +v
  EEA21678.1 339 ILRKLGLDPAKVNPLGGAIALGHPVGATgGRQTATLFAQLERQDKELGIVSMCASTGIGV 398
                 466777888888877777777777888844444667788888888888888888876665 PP

>> Thiolase_C  Thiolase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.3   0.0   4.9e-45   2.2e-41       2     121 ..     283     402 ..     282     404 .. 0.98

  Alignments for each domain:
  == domain 1  score: 140.3 bits;  conditional E-value: 4.9e-45
                 --SEEEEEEEEEE--GGGGGGHHHHHHHHHHHHHT--GGGESEEEE--SBHHHHHHHHHHHT--GGGBSTT--HHHH-B-TTTHHHHHHHHHHHHHHHC CS
  Thiolase_C   2 kplakirsyaevgvdpeilglgPayaikkvlkkagltvedidlfEinEAFaaqaLavakaldldlekvNvnGGaialGHPlGasGaRivvtllselkke 100
                 kp+++++  + +g  p+++g++P+yai+++lk +g++ +did+fEinEAFa+q+++ +++l+ld+ kvN  GGaialGHP+Ga+G R+++tl  +l+++
  EEA21678.1 283 KPIGRFVGTQIAGNAPDEMGISPVYAIPQLLKFTGIEQKDIDVFEINEAFASQTIYILRKLGLDPAKVNPLGGAIALGHPVGATGGRQTATLFAQLERQ 381
                 8899999******************************************************************************************** PP

                 TTSEEEEEEEETTTEEEEEEE CS
  Thiolase_C 101 ggklgvaalCigggqgvalvi 121
                 +++lg++++C+++g gva ++
  EEA21678.1 382 DKELGIVSMCASTGIGVASLF 402
                 ******************986 PP

>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   2.4e-06     0.011     174     212 ..     101     139 ..      80     142 .. 0.89

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 2.4e-06
                    GGGHHHHHHHHHHHHHHTTS-SEEEEEEEE---SHHHHH CS
  ketoacyl-synt 174 ACsSslvavhaavqslrsgeadvalaGGvellltpeava 212
                     CsS+l a+ ++ ++++ g++dv   GGve ++ + +++
     EEA21678.1 101 QCSSGLQAITHISHAIMVGQIDVGMGGGVESMTRWYTTR 139
                    6******************************99887765 PP

>> Prolactin_RP  Prolactin-releasing peptide
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.3     0.042   1.9e+02      18      24 ..     135     141 ..     133     143 .. 0.90
   2 ?    8.7   0.0   0.00029       1.3      18      30 ..     276     288 ..     275     298 .. 0.82
   3 ?   -2.7   0.0       1.1   4.8e+03      26      36 ..     362     372 ..     361     373 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.042
  Prolactin_RP  18 WYvGRgv 24 
                   WY+ Rg+
    EEA21678.1 135 WYTTRGI 141
                   ******9 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.00029
  Prolactin_RP  18 WYvGRgvRPvGRF 30 
                   W   Rg +P+GRF
    EEA21678.1 276 WAEERGLKPIGRF 288
                   7788********* PP

  == domain 3  score: -2.7 bits;  conditional E-value: 1.1
  Prolactin_RP  26 PvGRFGkRraa 36 
                   PvG  G R+ a
    EEA21678.1 362 PVGATGGRQTA 372
                   9**99999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (405 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       437  (0.0243739); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.47
# Mc/sec: 2612.77
//
Query:       EEA21679.1  [L=505]
Description: coenzyme A transferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
      8e-92  306.5   0.3    2.7e-54  183.8   0.1    2.0  2  CoA_trans  Coenzyme A transferase


Domain annotation for each model (and alignments):
>> CoA_trans  Coenzyme A transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  183.8   0.1   1.5e-58   2.7e-54       3     216 ..      34     261 ..      32     262 .. 0.98
   2 !  121.2   0.0   2.2e-39     4e-35       2     215 ..     293     489 ..     292     491 .. 0.95

  Alignments for each domain:
  == domain 1  score: 183.8 bits;  conditional E-value: 1.5e-58
                 HHHHHHCTT--TTEEEEE-SBTTBTHHHHHHHHHHHHT.TTSEEEEESTTTE..ECCHHHHHTTTEEEEEESCTTBBCEHHHHHHHHTTSSEEEEHHHH CS
   CoA_trans   3 taaeavakeikdGmtvavGGFgligiPealiaalarsg.vkdltviiseagv..lglgplllngsvkkviasyggetvnprfgkqflsgelefellpqg 98 
                 +a+ea++ ++k    ++vGGFg  g P++li+a+ ++   kd tv++++ag   +glg ll ++++ k++as++ge  n++f+k +l+g+l +el+pqg
  EEA21679.1  34 SAQEAIK-DLKGSTMILVGGFGFSGVPSSLINAVRDRPeLKDFTVVSNNAGMpgVGLGQLLETRQISKMVASFIGE--NKVFEKMYLEGDLALELTPQG 129
                 799***9.***************************98889************************************..********************* PP

                 HHHHHHHHHHHTEETTEEEESTTTTSHGGTT.................ESEEEEETTEEEEEEESSSEEEEEEECCEEETTCSEESSGGGHTTHSHHHH CS
   CoA_trans  99 tlaerlraGgaglpelgfltntgigtlvapk.................lkkvpgfgGaeyilepalkadvalikaskadeegnlvfeksagnfnkpaia 180
                 t+ae + aG+ag+p  +f+t+  +gt+++ +                 +k+ ++f+G++yile++  ad+a+++  kad+ gn +f+k+  nfn  a+a
  EEA21679.1 130 TIAEKCAAGAAGVP--AFYTPAAYGTIIQSGelpvrynkdgsvaemskPKESREFNGKQYILEESYFADYAFVRVAKADKLGNCQFRKAQNNFN-EAMA 225
                 **************..********************************99********************************************.8888 PP

                 HHEEEEEEEEEEEECTTSSECCCESBTGGGHSEEEE CS
   CoA_trans 181 eaakvtileveeivekgkldpekvliPgvlvdavve 216
                 ++akvt++e  eive+g+l pe+++  g++v +v++
  EEA21679.1 226 KNAKVTFVEADEIVEVGQLAPEEIHLQGIYVSKVIK 261
                 8*******************************9986 PP

  == domain 2  score: 121.2 bits;  conditional E-value: 2.2e-39
                 CHHHHHHCTT--TTEEEEE-SBTTBTHHHHHHHHHHHHTTTSEEEEESTTTEECCHHHHHTTTEEEEEESCTTBBCEHHHHHHHHTTSSEEEEHHHHHH CS
   CoA_trans   2 etaaeavakeikdGmtvavGGFgligiPealiaalarsgvkdltviiseagvlglgplllngsvkkviasyggetvnprfgkqflsgelefellpqgtl 100
                 e++ +++ake++dGm+v++G    ig+P   + a ++     ++v++se+g+lglg ++++g+++ ++++ g+etv+   g++++++ ++f  +++ ++
  EEA21679.1 293 ERIVKRAAKEFEDGMYVNLG----IGMP-LVAPAFLPE--GIEVVLQSENGILGLGGYPRPGEEDPDLINPGKETVTLASGASVFGSHESFG-MIRSGR 383
                 678899999***********....****.*********..889*************************************************.****** PP

                 HHHHHHHHHTEETTEEEESTTTTSHGGTTESEEEEETTEEE.EEEESSSEEEEEEECCEEETTCSEESSGGGHTTHSHHHHHHEEEEEEEEEEEECTTS CS
   CoA_trans 101 aerlraGgaglpelgfltntgigtlvapklkkvpgfgGaey.ilepalkadvalikaskadeegnlvfeksagnfnkpaiaeaakvtileveeivekgk 198
                 ++ +++G+++++++g+l+n +++     +  kv+g+gGa++ +++p+++ +v++++++ +++ +++  e+s + ++ +++   +++t+l+v+++   ++
  EEA21679.1 384 IDLTMLGALQVSQYGDLANFMLP-----G--KVKGVGGAMDlVANPSKTRVVVTMEHVDRKGNPKILEECSFPLTGPLCVW--KIITDLAVFNV-HPTE 472
                 ***********************.....5..7*******9835788999***************************55555..9**********.79** PP

                 SECCCESBTGGGHSEEE CS
   CoA_trans 199 ldpekvliPgvlvdavv 215
                  +++ ++ +g++v++v+
  EEA21679.1 473 GLTLVEVAEGSTVEEVK 489
                 ***************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (505 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       489  (0.0272742); expected 358.6 (0.02)
Passed bias filter:                      439  (0.0244855); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.32s 00:00:00.90 Elapsed: 00:00:00.49
# Mc/sec: 3122.45
//
Query:       EEA21680.1  [L=1068]
Description: alpha methylacyl-CoA racemase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   3.4e-108  362.1   0.0   4.9e-108  361.5   0.0    1.2  1  CoA_transf_3   CoA-transferase family III
    7.3e-27   93.8   0.0    1.3e-26   93.0   0.0    1.4  1  FAD_binding_4  FAD binding domain
    5.1e-16   59.0   0.0    8.7e-16   58.3   0.0    1.3  1  FAD-oxidase_C  FAD linked oxidases, C-terminal domain


Domain annotation for each model (and alignments):
>> CoA_transf_3  CoA-transferase family III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  361.5   0.0  8.2e-112  4.9e-108      27     368 .]     693    1043 ..     693    1043 .. 0.98

  Alignments for each domain:
  == domain 1  score: 361.5 bits;  conditional E-value: 8.2e-112
  CoA_transf_3   27 AeVIkvEppkkgDpaRkvgpsee........kgesayflavnrnKrsvalDlkseegrellkrLvakADVvieNfrpgvlerlglgyeelrainP 113 
                    A++IkvE+p++gD++R++gp +          gesay+l+vnrnK+s+ l + ++eg e+l++L++++DV++eN+ pg l+++ ++ye++r+ nP
    EEA21680.1  693 ADIIKVEHPERGDDTRAWGPPFAeykdgregPGESAYYLSVNRNKKSLGLSFAHPEGVEILHELAKNCDVLVENYLPGSLKKYNMDYESIRKLNP 787 
                    9*******************9999*********************************************************************** PP

  CoA_transf_3  114 rLiyasvsgyGqsGpkakrpgyDlvaqaasGlmsltgepdgpPvkvgvplgDivtgllaavailaallarertGkGqvidvslleaalallapql 208 
                    rLiyas++gyGq+Gp+++rpg+D++++a++Glm+ltg+ dgpPvkvgv+++D +tgl+a+++i+aallar +tG+Gq+ dv l +  +a+la+ +
    EEA21680.1  788 RLIYASITGYGQTGPYSNRPGFDVMVEAEFGLMHLTGSRDGPPVKVGVAVTDLTTGLYACNSIMAALLARANTGEGQHLDVCLSDVQTATLANMA 882 
                    *********************************************************************************************** PP

  CoA_transf_3  209 leylatgevperq.gnrdpaaapygvyrtkdgwvaiaaatdkqwaalckalgrpelaedprfatnasrlenraeldaelaewlaertaaewlell 302 
                       l +g+  + + g ++p++ py+ ++t+dg ++++ a+d+ +  lc+ lg+ e+ +dp++ tn++r++nr+el++++++ + +rt++ewle+l
    EEA21680.1  883 ESVLISGKPDSGRwGTAHPSVVPYQGFKTSDGDIFLGGANDRLFGILCEKLGKSEWSKDPKYVTNNERVRNRKELEDLIEAETTKRTTQEWLEIL 977 
                    99966666666444********************************************************************************* PP

  CoA_transf_3  303 aaagvpaapvntleevlddpqlaarglvvevddpdygevpvvglpvrlsetparvkraaPklGedt 368 
                    +  g+p a+vn++  +l++++++arg+v+e+d+p  g+++v + pv++s++++ +++++P lGe+t
    EEA21680.1  978 EGSGLPYAAVNDVLGTLNHEHTKARGMVQEIDHPSCGPIKVLSPPVKYSNADPSIRSPPPLLGEHT 1043
                    *****************************************************************8 PP

>> FAD_binding_4  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.0   0.0   2.2e-30   1.3e-26       2     139 .]     109     249 ..     108     249 .. 0.94

  Alignments for each domain:
  == domain 1  score: 93.0 bits;  conditional E-value: 2.2e-30
                    EEEEEESSHHHHHHHHHHHHHCTSCEEEESSSTTEE.STTC..SCCEEEEEETT.S--EEEEETTTTEEEEETTSBHHHHHHHHHHHTTE.CSSGG CS
  FAD_binding_4   2 aavvrpeseeevaaalrlaneaglpvlvrGgGssll.gqav..atggvvldlsr.lnrileideeegtatveaGvtlgdlvealaakgll.lglep 92 
                    +avv+p+s+eev++++ +an++++p+ +++ G +l+ g+a    +g vv+dl r +n+il+i++ ++t+ ve+Gvt+ +l+e+++++g+  l++++
     EEA21680.1 109 SAVVYPGSTEEVQKIVLWANKYKVPIFPISIGRNLGyGGAAprVRGSVVIDLGRrMNKILDINPVDHTCLVEPGVTFYALYEEIQRRGYKhLWIDC 204
                    79***********************************9999999999*****988********************************996589999 PP

                    GTTCGSBHHHTTTTT-EETTEEGG--HHGTEEEEEEEETTSEEEEEE CS
  FAD_binding_4  93 gsgipgtvGGaiatnagGygsekyGlirdnvlglevvladGevvrls 139
                     ++  g+v G+++ +++G   ++yG++  +  glevvl++Ge++r++
     EEA21680.1 205 PDLGGGSVLGNTLDRGIG--YTVYGDHWACHSGLEVVLPTGELIRTG 249
                    999999999999998888..778999******************985 PP

>> FAD-oxidase_C  FAD linked oxidases, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.3   0.0   1.5e-19   8.7e-16     126     249 ..     444     569 ..     431     570 .. 0.95

  Alignments for each domain:
  == domain 1  score: 58.3 bits;  conditional E-value: 1.5e-19
                    TTEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHEEEEEEEEEE..TTEEEEEEEEEEE..--TT--THHHHHHHHHHHHTT---------------- CS
  FAD-oxidase_C 126 agvavlseDtsvPvsrladlvrdikalldkyglevvlfgHag..dgnlhlyilfdladeaeeeraeklvdevvdlavelgGsisgEHGvGldkkay 219
                     g++++s+ + v  +++ +l+r ++ +++++g++++  + +g  +++l++ + fd++d++ +++a + +  + d+a++ g   +++H v +d++a+
     EEA21680.1 444 GGHIAFSPVSPVRGADATELWRIARSRAAEFGHDIFPAFCVGlrEMHLIVECVFDRDDPDSRKKALACMRAMIDEAASKGYGEYRTHLVLMDQIAK 539
                    678888888888899999**************999999999999**************************************************** PP

                    -------THHHHHHHHHHHH-TT--BSTT- CS
  FAD-oxidase_C 220 lerekgeeglalmrriKaalDPkgiLNPgk 249
                    ++ ++++++++   riK++lDP+giL+Pgk
     EEA21680.1 540 TYDFNDHALMKFNERIKDTLDPNGILAPGK 569
                    *****************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1068 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       540  (0.0301188); expected 358.6 (0.02)
Passed bias filter:                      524  (0.0292264); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.79u 0.30s 00:00:01.09 Elapsed: 00:00:00.46
# Mc/sec: 6908.09
//
Query:       EEA21681.1  [L=258]
Description: C6 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (258 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       881  (0.0491383); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 1721.94
//
Query:       EEA21682.1  [L=587]
Description: fungal specific transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.3e-21   76.8   0.2      2e-21   76.2   0.2    1.4  1  Fungal_trans  Fungal specific transcription factor domain
  ------ inclusion threshold ------
      0.075   13.0   0.0       0.44   10.5   0.0    2.2  3  IBN_N         Importin-beta N-terminal domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.2   0.2   2.2e-25     2e-21       2     192 ..     117     304 ..     116     383 .. 0.78

  Alignments for each domain:
  == domain 1  score: 76.2 bits;  conditional E-value: 2.2e-25
  Fungal_trans   2 drffsnfhpqfpilhkpsflpkt........ssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspsss 90 
                    ++f+ +hp+fp+lh psfl+          ++++ sk+ + ++ + ++ +    +  +s+ + +  +l +    +i    +a++l +++   ++ +
    EEA21682.1 117 MTYFKIWHPLFPFLHGPSFLHAMeafysegsAGDELSKAVSEHHRVCWSAIFQCIFNISSTLQPD-LQLAQR--AKI--TSAADALKLANVLLNRHD 208
                   58***********************7777664444444444444444444443333333333333.222222..233..3366666677999***** PP

  Fungal_trans  91 lwilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPc 187
                   + +lq+ l ++ly+ +s + + + ++ g+ +r + + g+hr+p++++     +l++++ + r+R++w+ + +D++++  lG p  + ds+i++ LP 
    EEA21682.1 209 ILSLQAILAIQLYLVASMSLRNASLLGGTILRAVLHAGFHRCPFRYQ-----QLSAHDCQLRKRIFWCFYAIDRYLSQALGLPLGIQDSDIDVCLPG 300
                   **********************************************9.....6*******************************88*********97 PP

  Fungal_trans 188 ddddl 192
                   + + +
    EEA21682.1 301 SPE-I 304
                   766.5 PP

>> IBN_N  Importin-beta N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       0.4   3.6e+03      25      48 ..      22      44 ..      12      56 .. 0.74
   2 ?   -3.6   0.0       1.2   1.1e+04      24      48 ..     225     248 ..     218     261 .. 0.68
   3 ?   10.5   0.0   4.9e-05      0.44      17      60 ..     370     407 ..     355     410 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.4
                TTSHHHHHHHHHHHHHHHHHHHGG CS
       IBN_N 25 seselevRqlAalyLknlitkhWs 48
                +es+  v  ++++ + n++++ + 
  EEA21682.1 22 DESQ-FVGSSSGVFFVNTVRRAFA 44
                3333.6668899999999999876 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 1.2
                 CTTSHHHHHHHHHHHHHHHHHHHGG CS
       IBN_N  24 nseselevRqlAalyLknlitkhWs 48 
                 + ++  ++ +l++++L+  +++ ++
  EEA21682.1 225 SMSLR-NASLLGGTILRAVLHAGFH 248
                 44444.5557788888877777665 PP

  == domain 3  score: 10.5 bits;  conditional E-value: 4.9e-05
                 HHHHHHHCTTSHHHHHHHHHHHHHHHHHHHGGSCCCHCGSXHHH CS
       IBN_N  17 allqilanseselevRqlAalyLknlitkhWsdeeekqslpsee 60 
                 + l+++++s+++ e+R +A+lyL   ++k W+      +lps +
  EEA21682.1 370 RALELFHKSTHSREIRRSAVLYLVSDVHKWWN------NLPSTQ 407
                 6789999*************************......999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (587 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       435  (0.0242624); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.40
# Mc/sec: 4357.81
//
Query:       EEA21683.1  [L=664]
Description: GARP complex subunit (Sac2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
   7.5e-120  401.1   0.0   9.3e-120  400.7   0.0    1.0  1  Vps52       Vps52 / Sac2 family
    0.00053   18.5   3.5     0.0014   17.1   3.6    1.5  1  Sec3_C      Exocyst complex component Sec3
  ------ inclusion threshold ------
      0.074   13.5   1.2          8    6.9   1.2    2.9  1  MitMem_reg  Maintenance of mitochondrial structure and functi
       0.13   12.3   1.4       0.48   10.4   0.1    2.2  2  Laminin_II  Laminin Domain II
       0.15   11.0   1.3       0.32    9.8   0.3    1.9  2  Spc7        Spc7 kinetochore protein
        1.7    7.6   5.1        1.7    7.6   0.0    2.9  4  Exo70       Exo70 exocyst complex subunit


Domain annotation for each model (and alignments):
>> Vps52  Vps52 / Sac2 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  400.7   0.0  3.1e-123  9.3e-120      13     503 ..     159     661 ..     151     664 .] 0.91

  Alignments for each domain:
  == domain 1  score: 400.7 bits;  conditional E-value: 3.1e-123
       Vps52  13 seniaslhnqiaaidsvleqledlLeeFqsdlssissdikklqekSnelqlrLenrkaveaklsklvddlivppelidvIiegkvneesiaekleilnk 111
                  ++ ++lhn ia++d+vl+ +e++L++Fq +l+ +s +i++lq +S++l+ +Lenr+ ve  l++ v+d+ ++p+ i +I +g ++e+ +a++l ++++
  EEA21683.1 159 QDKFQELHNAIADCDEVLKSVESYLSDFQTELGIVSAEIETLQTRSVQLNAKLENRRNVERLLGPAVEDISISPNAIRTITDGLIDEK-WAKALSEIEA 256
                 567889*******************************************************************************986.7777777777 PP

       Vps52 112 kksaekdqsvkslkalkDvkklldkLrnkalekireyivqkiktlRkpkvnvqiiqn.kLlkvkkifeFllennrklalelrqaYidTmkkiyleyfrs 209
                   +  +    + lka  Dvk+ll  L+nka  +ir+y+v++ik++R+p+ n q iq+ +L+k+k +++Fl      l  e+ qaY++Tm ++yl+ f +
  EEA21683.1 257 RSASIEKSTGSPLKAVDDVKPLLVELKNKATIRIRDYLVSQIKAMRSPNMNAQYIQQhHLVKYKDLYSFLTRTHPTLSEEITQAYVNTMRWYYLSNFTR 355
                 666666677899*********************************************9***************************************** PP

       Vps52 210 YirsLtklqfeeietkddLigvedtakklffsktaslkkrnkiftigkRlkilkaqldapvlv.phiaeknttkyyiEalfrslelalldnatsEYlFl 307
                 Y+++L+kl+++ ++t++ L g    + ++              ftig+R+++lk    +p+ + + iae+++  + +E+ fr  +lal+dn++ EY Fl
  EEA21683.1 356 YSQALEKLKLHPSDTNNVLGGDPSAQRGGTGPG--GRGISHDPFTIGRRIDVLK--TGNPIAIsSYIAEEDKSVHGFEVPFRHFNLALVDNVSAEYSFL 450
                 ****************66655545555554433..34445568***********..77787762579****99************************** PP

       Vps52 308 kefFavsgdqaeei.feqifektlslatkyleqlisdcyDaigvllsIriinrlqleaerrrvPvldsylnsvlillWPRFqlvldlnveSlrkaditt 405
                 +e F v+  q+ +   ++ife+ + l ++ +++l++++ D++gvll++r+ +r ++e +rr+vPv +sy n+++++lWPRFq ++dl+++Sl+  +   
  EEA21683.1 451 TEMFSVRSYQQISRkAAEIFEPVFALGQTVTKHLVENTTDCLGVLLCVRLNQRAAFELQRRKVPVAESYINGINMQLWPRFQKIMDLHCDSLKRLASGA 549
                 ******87766554699***************************************************************************9977766 PP

       Vps52 406 lve............kdtrPHeltrryaeflsslvtlsvtvkeee.verllerlqreveslilrlaklfkkkkeqlvfLinNYdlllgvLkelsldlsk 491
                                + + PH lt+r++++l  +++ls +  ++e v+++l rl+ e + l+++l++ + ++k+ ++fL nNY l+l++++++ ++l+ 
  EEA21683.1 550 ARSsvsalsltddskQSSAPHFLTQRFGQLLHGILSLSSEGGDDEpVSISLGRLRGEFDALLTKLSRGSGDPKRRERFLYNNYSLILTIISDTDGKLAA 648
                 6666778******999999***********************9999***************************************************99 PP

       Vps52 492 eqed.fqeklnen 503
                 eq++ f ++l++ 
  EEA21683.1 649 EQKEhFTKQLKNA 661
                 9875155555544 PP

>> Sec3_C  Exocyst complex component Sec3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   3.6   4.7e-07    0.0014      21     255 ..     151     361 ..     144     374 .. 0.80

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 4.7e-07
      Sec3_C  21 nikrllesdkkveelkkdidkalkecdeldalltlysveLstlsedieyIEsqnngLQvksaNqklLykeLeellstvslsesdleaLkeaelssangl 119
                 +i+++   ++k++el + i ++ + +  +++ l+ ++ eL+ +s +ie+  + +  L  k  N++     L   ++ +s+s++++++++++ ++++   
  EEA21683.1 151 TIEQFAGDQDKFQELHNAIADCDEVLKSVESYLSDFQTELGIVSAEIETLQTRSVQLNAKLENRRNVERLLGPAVEDISISPNAIRTITDGLIDEKW-- 247
                 57777777788888888888887778888999***********************************************************998876.. PP

      Sec3_C 120 ealeealeaLfkAltaIdsdlk.dlesdlgemravkerrerYekvsssFlrrlveflekkfksaekelgkdldsatkkklslekhlevlnlLliYsgLi 217
                            kAl  I++     ++s  ++++av + +    + +++ + r+ ++l +++k ++             ++++++       L++Y+ L 
  EEA21683.1 248 ----------AKALSEIEARSAsIEKSTGSPLKAVDDVKPLLVELKNKATIRIRDYLVSQIKAMR-------------SPNMNAQYIQQHHLVKYKDLY 323
                 ..........3333333333332455777799999999999999999999999999999996662.............333333333445689999999 PP

      Sec3_C 218 lflKevdaekfeallqqYnasiskvYereikeffeslk 255
                  fl    ++  e++ q+Y + ++ +Y + ++   ++l 
  EEA21683.1 324 SFLTRTHPTLSEEITQAYVNTMRWYYLSNFTRYSQALE 361
                 99999999999999999999999999888887766665 PP

>> MitMem_reg  Maintenance of mitochondrial structure and function
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   1.2    0.0027         8      59     110 ..     313     363 ..     159     364 .. 0.57

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0027
  MitMem_reg  59 heilrnlqkllnllPhleteelekefnvetnDvllvvyLasltrsilalnel 110
                 ++ l + ++l + l      +l++e+++ + +++   yL++ tr  +al++l
  EEA21683.1 313 QHHLVKYKDLYSFLTRTH-PTLSEEITQAYVNTMRWYYLSNFTRYSQALEKL 363
                 112333333332232222.246778889999999999999999999999876 PP

>> Laminin_II  Laminin Domain II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.1   0.00016      0.48       3      65 ..     167     229 ..     166     237 .. 0.91
   2 ?    0.0   0.1      0.27     8e+02      27      77 ..     245     300 ..     243     314 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00016
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX- CS
  Laminin_II   3 elaaeanetakevleqlaplsqnlentkeklseinrsveetnekvkdankairdArrsvkkLe 65 
                 + +a+ +e +k+v++ l + +++l  ++++++++++   + n+k+++  ++ r+ + +v ++ 
  EEA21683.1 167 NAIADCDEVLKSVESYLSDFQTELGIVSAEIETLQTRSVQLNAKLENRRNVERLLGPAVEDIS 229
                 568999*******************************9*********9999999998888765 PP

  == domain 2  score: 0.0 bits;  conditional E-value: 0.27
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--TT.....TTTGGGHHH CS
  Laminin_II  27 entkeklseinrsveetnekvkdankairdArrsvkkLekla.....pqLldklke 77 
                 e++ + lsei++  + +++   +  ka++d++   ++L+++a     + L++++k 
  EEA21683.1 245 EKWAKALSEIEARSASIEKSTGSPLKAVDDVKPLLVELKNKAtirirDYLVSQIKA 300
                 57899999999999999999999999999999999999988733333445555555 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.3   0.00011      0.32     197     256 ..     158     217 ..     144     241 .. 0.88
   2 ?   -1.0   0.0      0.21   6.1e+02     239     289 ..     243     293 ..     234     308 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00011
        Spc7 197 dkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaerv 256
                 d+++ +el++++a++++ +++ +  l++ q++l  ++++ie+l+++  +l++++++ ++v
  EEA21683.1 158 DQDKFQELHNAIADCDEVLKSVESYLSDFQTELGIVSAEIETLQTRSVQLNAKLENRRNV 217
                 899************************************************999966554 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.21
        Spc7 239 lkeqkseleeeiaeaervleeckgwsesevsrlkeevkaleeltgwkivsl 289
                 ++e+ +++ +ei++    +e+  g+  + v+ +k  + +l+++  ++i   
  EEA21683.1 243 IDEKWAKALSEIEARSASIEKSTGSPLKAVDDVKPLLVELKNKATIRIRDY 293
                 567888999999999999999999999999999999999999999998765 PP

>> Exo70  Exo70 exocyst complex subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0      0.72   2.1e+03     257     291 ..     233     267 ..     209     287 .. 0.67
   2 ?   -2.1   0.1      0.51   1.5e+03     138     148 ..     335     345 ..     273     372 .. 0.57
   3 ?    1.0   0.1     0.059   1.8e+02       6      74 ..     434     496 ..     430     510 .. 0.75
   4 ?    7.6   0.0   0.00056       1.7     193     247 ..     597     648 ..     532     664 .] 0.65

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.72
       Exo70 257 kkikqyaksYeresWskvlslLkdegltssskkls 291
                 ++i+  ++   +e W+k+ls + + +   +++ +s
  EEA21683.1 233 NAIRTITDGLIDEKWAKALSEIEARSASIEKSTGS 267
                 67888899999999999999888866555444444 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.51
       Exo70 138 ggvheltrnvm 148
                 +++++  +n+m
  EEA21683.1 335 EEITQAYVNTM 345
                 22333333333 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 0.059
       Exo70   6 ayktavkvlfasErrlleqifgeseseresvfaeiakesitellqllrefgeavakkskr.speklfklL 74 
                 ++  a+   + +E+++l ++f+        ++++i++++++ +   +  +g++v+k++ + ++++l +lL
  EEA21683.1 434 HFNLALVDNVSAEYSFLTEMFS------VRSYQQISRKAAEIFEPVFA-LGQTVTKHLVEnTTDCLGVLL 496
                 5666777778899999999997......77777888887755555555.888777777665888888876 PP

  == domain 4  score: 7.6 bits;  conditional E-value: 0.00056
       Exo70 193 sllalfladlisaLesnLeakaklykdkslqgiFlmNNlhyilqkvkrselklll 247
                 s+   +l+   +aL+++L + +    d+  +  Fl NN+++il+++ +++ kl  
  EEA21683.1 597 SISLGRLRGEFDALLTKLSRGS---GDPKRRERFLYNNYSLILTIISDTDGKLAA 648
                 5555555555666666666665...56999****************999876665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (664 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       828  (0.0461822); expected 358.6 (0.02)
Passed bias filter:                      663  (0.0369792); expected 358.6 (0.02)
Passed Vit filter:                        71  (0.00396006); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.72u 0.27s 00:00:00.99 Elapsed: 00:00:00.43
# Mc/sec: 4610.81
//
Query:       EEA21684.1  [L=162]
Description: Eukaryotic translation initiation factor eIF-5A [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-27   95.9   1.5    1.6e-27   95.4   1.5    1.2  1  eIF-5a    Eukaryotic elongation factor 5A hypusine, DNA-bindi
     0.0048   16.9   0.1       0.01   15.8   0.0    1.6  2  EFP_N     Elongation factor P (EF-P) KOW-like domain


Domain annotation for each model (and alignments):
>> eIF-5a  Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.4   1.5   1.8e-31   1.6e-27       1      69 []      87     156 ..      87     156 .. 0.98

  Alignments for each domain:
  == domain 1  score: 95.4 bits;  conditional E-value: 1.8e-31
                 --EEEEEEEEEE-SS.EEEEEETT--EEE.EEGG..GB-HHHHTT-.-TT-E..EEEEEETTEEEEEEE- CS
      eIF-5a   1 nVkrkeyqLidIqdDgflsLmdddgetkeDlklpegelgkqikekf.eegkdvlVtVlsamGeekiiavK 69 
                 nV rke+qL+d++dDgflsLmd+ g+tk+D+k p+ge+g++i + f eegkdv+VtV+samGee ++++K
  EEA21684.1  87 NVFRKEFQLLDVTDDGFLSLMDEAGNTKDDVKKPDGEIGDRIDKLFtEEGKDVNVTVMSAMGEEVAVEAK 156
                 689*******************************************999*****************9987 PP

>> EFP_N  Elongation factor P (EF-P) KOW-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0       1.3   1.2e+04      46      56 ..       5      15 ..       2      15 .. 0.72
   2 !   15.8   0.0   1.2e-06      0.01       3      49 ..      27      74 ..      25      80 .. 0.86

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 1.3
                -EEEEEEETT- CS
       EFP_N 46 akvektfkagd 56
                a  e+tf + d
  EEA21684.1  5 AQHEHTFESAD 15
                55688998876 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 1.2e-06
                GG--TT-EEEETTEEEEEEEEEEEEETT.S--EEEEEEEETTTS-EEE CS
       EFP_N  3 selkkGlvieidgklyvVlefehvkpGk.GqafvrvklknlrtGakve 49
                s l+k+  + i+g ++++++   +k Gk G a v     ++ tG+k+e
  EEA21684.1 27 SALRKNGYVVIKGRPCKIVDMSTSKTGKhGHAKVHLVAIDIFTGKKLE 74
                6799*********************99637788888888888888877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (162 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       471  (0.0262703); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1197.68
//
Query:       EEA21685.1  [L=139]
Description: Eukaryotic translation initiation factor eIF-5A [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.9e-28   96.4   1.5    1.1e-27   95.9   1.5    1.2  1  eIF-5a    Eukaryotic elongation factor 5A hypusine, DNA-bindi
     0.0048   16.9   0.0     0.0076   16.3   0.0    1.3  1  EFP_N     Elongation factor P (EF-P) KOW-like domain


Domain annotation for each model (and alignments):
>> eIF-5a  Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.9   1.5   1.2e-31   1.1e-27       1      69 []      64     133 ..      64     133 .. 0.98

  Alignments for each domain:
  == domain 1  score: 95.9 bits;  conditional E-value: 1.2e-31
                 --EEEEEEEEEE-SS.EEEEEETT--EEE.EEGG..GB-HHHHTT-.-TT-E..EEEEEETTEEEEEEE- CS
      eIF-5a   1 nVkrkeyqLidIqdDgflsLmdddgetkeDlklpegelgkqikekf.eegkdvlVtVlsamGeekiiavK 69 
                 nV rke+qL+d++dDgflsLmd+ g+tk+D+k p+ge+g++i + f eegkdv+VtV+samGee ++++K
  EEA21685.1  64 NVFRKEFQLLDVTDDGFLSLMDEAGNTKDDVKKPDGEIGDRIDKLFtEEGKDVNVTVMSAMGEEVAVEAK 133
                 689*******************************************999*****************9987 PP

>> EFP_N  Elongation factor P (EF-P) KOW-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   8.5e-07    0.0076       3      49 ..       4      51 ..       2      57 .. 0.86

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 8.5e-07
                GG--TT-EEEETTEEEEEEEEEEEEETT.S--EEEEEEEETTTS-EEE CS
       EFP_N  3 selkkGlvieidgklyvVlefehvkpGk.GqafvrvklknlrtGakve 49
                s l+k+  + i+g ++++++   +k Gk G a v     ++ tG+k+e
  EEA21685.1  4 SALRKNGYVVIKGRPCKIVDMSTSKTGKhGHAKVHLVAIDIFTGKKLE 51
                6799*********************99637788888888888888877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (139 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       355  (0.0198003); expected 358.6 (0.02)
Passed bias filter:                      302  (0.0168442); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.38u 0.23s 00:00:00.61 Elapsed: 00:00:00.39
# Mc/sec: 1057.87
//
Query:       EEA21686.1  [L=544]
Description: RNA polymerase I specific transcription initiation factor Rrn7, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.3e-08   31.6   4.6    1.5e-07   31.0   4.6    1.3  1  zf-RRN7   Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn


Domain annotation for each model (and alignments):
>> zf-RRN7  Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.0   4.6   8.2e-12   1.5e-07       3      32 .]       5      36 ..       3      36 .. 0.92

  Alignments for each domain:
  == domain 1  score: 31.0 bits;  conditional E-value: 8.2e-12
     zf-RRN7  3 kgppCgvCgc..rsftlddGfyyCrrChtqeg 32
                k+ pCg++gc   +++ld+G ++Crr+h+qeg
  EEA21686.1  5 KRGPCGQEGCreIRYYLDNGIWFCRRGHQQEG 36
                789*******856*****************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (544 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       490  (0.02733); expected 358.6 (0.02)
Passed bias filter:                      389  (0.0216967); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.23s 00:00:00.77 Elapsed: 00:00:00.40
# Mc/sec: 4101.26
//
Query:       EEA21687.1  [L=128]
Description: ubiquitin UbiA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.7e-34  116.3   0.6    4.9e-34  115.9   0.6    1.2  1  ubiquitin       Ubiquitin family
    9.2e-31  105.5  11.4    1.4e-30  104.9  11.4    1.3  1  Ribosomal_L40e  Ribosomal L40e family
      3e-16   59.0   0.7      3e-16   59.0   0.7    1.5  2  Rad60-SLD       Ubiquitin-2 like Rad60 SUMO-like
      2e-05   24.9   0.1    7.4e-05   23.1   0.1    1.8  1  Ubiquitin_2     Ubiquitin-like domain
     0.0037   17.6   0.0     0.0055   17.0   0.0    1.3  1  Ubiquitin_5     Ubiquitin-like domain
     0.0039   17.1   0.0     0.0051   16.7   0.0    1.3  1  TBK1_ULD        TANK binding kinase 1 ubiquitin-like domain
     0.0057   16.7   0.0      0.012   15.7   0.0    1.6  1  Rad60-SLD_2     Ubiquitin-2 like Rad60 SUMO-like
  ------ inclusion threshold ------
      0.014   15.4   1.0        4.2    7.5   0.2    2.2  2  Ubiquitin_4     Ubiquitin-like domain
      0.026   15.1   0.1      0.032   14.8   0.1    1.3  1  DUF2407         DUF2407 ubiquitin-like domain
       0.08   12.8   0.0       0.11   12.3   0.0    1.2  1  Sde2_N_Ubi      Silencing defective 2 N-terminal ubiquitin do


Domain annotation for each model (and alignments):
>> ubiquitin  Ubiquitin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.9   0.6   2.7e-37   4.9e-34       1      72 []       3      74 ..       3      74 .. 0.99

  Alignments for each domain:
  == domain 1  score: 115.9 bits;  conditional E-value: 2.7e-37
                EEEEETTSEEEEEEEETTSBHHHHHHHHHHHHTSSGGGEEEEETTEEE-TTSBHGGHTTSTTEEEEEEESSC CS
   ubiquitin  1 itvktldgkkitleveesdtveelKekiaekegipaeqqrLiysGkvLedertleeygiqdgstlhlvlrlr 72
                i+vktl+gk+itleve+sdt++++K ki++kegip++qqrLi++Gk+Led rtl++y+iq++stlhlvlrlr
  EEA21687.1  3 IFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLR 74
                9********************************************************************986 PP

>> Ribosomal_L40e  Ribosomal L40e family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.9  11.4   7.8e-34   1.4e-30       1      50 []      78     127 ..      78     127 .. 0.99

  Alignments for each domain:
  == domain 1  score: 104.9 bits;  conditional E-value: 7.8e-34
  Ribosomal_L40e   1 iepsLrqLAqKyncdKmiCrkCYArlpprAtnCrkkkCghsnnlrpKKkl 50 
                     iepsL++LA+Kync+K+iCrkCYArlpprAtnCrk+kCgh+n+lrpKKkl
      EEA21687.1  78 IEPSLKALASKYNCEKSICRKCYARLPPRATNCRKRKCGHTNQLRPKKKL 127
                     8***********************************************96 PP

>> Rad60-SLD  Ubiquitin-2 like Rad60 SUMO-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.0   0.7   1.7e-19     3e-16       1      72 []       1      71 [.       1      71 [. 0.98
   2 ?   -2.4   0.0       2.4   4.3e+03      23      39 ..      82      98 ..      81     103 .. 0.73

  Alignments for each domain:
  == domain 1  score: 59.0 bits;  conditional E-value: 1.7e-19
                EEEEEEESSS--EEEEEETTSBHHHHHHHHHHHHT----TT-EEEETTEE--TTSBGGGSS--TTEEEEEEX CS
   Rad60-SLD  1 ikiilkgkdgkevkikVkptttvskLieayrkkkgipeeqkvrLiFDGeeLdpnstvedldiedgdtidvvi 72
                ++i++k+ +gk+++++V+++ t+ +++++ ++k+gip+ +++rLiF G++L++  t+ d+ i++++t+++v+
  EEA21687.1  1 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPP-DQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVL 71
                89************************************.******************************996 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 2.4
                HHHHHHHHHHHHT---- CS
   Rad60-SLD 23 vskLieayrkkkgipee 39
                ++ L+++y  +k+i ++
  EEA21687.1 82 LKALASKYNCEKSICRK 98
                67899999988888665 PP

>> Ubiquitin_2  Ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.1   0.1   4.1e-08   7.4e-05      15      80 ..      12      69 ..       1      70 [. 0.85

  Alignments for each domain:
  == domain 1  score: 23.1 bits;  conditional E-value: 4.1e-08
                 EEEEEEETTSBHHHHHHHHHHHH---TTCEEEEEE.-SSSSEEECSSGCCSBCCCCT--TTEEEEE CS
  Ubiquitin_2 15 sserrfsksltieelKekLelitGtspasmrLqlyddkkdnevsklddddalLgsYgvkdgmrihV 80
                   +  +++s+ti+++K+k++   G++p+++rL +          k  +d ++L++Y+++  +++h 
   EEA21687.1 12 TITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFA--------GKQLEDGRTLSDYNIQKESTLHL 69
                 556678899************************99........5667899**********999995 PP

>> Ubiquitin_5  Ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0   3.1e-06    0.0055      34      92 ..      13      72 ..       4      76 .. 0.83

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 3.1e-06
  Ubiquitin_5 34 klletkLdvtgkelvskiaeefglkensiKlilngklleldktLeeQgvknnskv.mvLk 92
                  +le++ + t +++ ski ++ g+  ++ +li  gk+le ++tL + +++++s + +vL+
   EEA21687.1 13 ITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLhLVLR 72
                 566666677888999999******99***********************99987546666 PP

>> TBK1_ULD  TANK binding kinase 1 ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   2.9e-06    0.0051      19      53 ..      17      51 ..       3      72 .. 0.85

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 2.9e-06
    TBK1_ULD 19 ihpyntvaifqeevakqTkiaaekQellfeghrll 53
                +++ +t++++  +++++  i++++Q l+f g++l 
  EEA21687.1 17 VESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLE 51
                6789****************************973 PP

>> Rad60-SLD_2  Ubiquitin-2 like Rad60 SUMO-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   6.6e-06     0.012      13      88 ..      11      72 ..       2      99 .. 0.69

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 6.6e-06
                 -EEEEEEEETT-BHHHHHHHHHHHS-TT-SSS--SCCCEEEEETTEEE-TTSBCCCCS-TTTTTTTS-EEEEEEE- CS
  Rad60-SLD_2 13 sDigpvkfsdaatvaelkekviaqWPkdkeekpksvndlklilaGkiLennktlkelrlplgevkggvtvmHvvvr 88
                 + +  ++ ++++t++++k k+     +dke  p  +++ +li aGk Le+ +tl++++++        +++H+v+r
   EEA21687.1 11 K-TITLEVESSDTIDNVKSKI-----QDKEGIP--PDQQRLIFAGKQLEDGRTLSDYNIQKE------STLHLVLR 72
                 5.5556667777777777777.....4555533..34559*****************55433......45777765 PP

>> Ubiquitin_4  Ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   0.2    0.0024       4.2       1      32 [.       1      32 [.       1      36 [. 0.94
   2 ?    6.8   0.0    0.0037       6.6      58      86 ..      43      70 ..      39      73 .. 0.84

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0024
  Ubiquitin_4  1 lkvtvkkldgeslevvvkqnatvkdLkkaier 32
                 +++ vk l g+++ ++v+++ t+ ++k  i+ 
   EEA21687.1  1 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQD 32
                 7899*************************997 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.0037
  Ubiquitin_4 58 LsfegekLkddkaklkeygirnkselsFv 86
                 L+f g++L+ d  +l++y i+++s+l+ v
   EEA21687.1 43 LIFAGKQLE-DGRTLSDYNIQKESTLHLV 70
                 889999986.6789************976 PP

>> DUF2407  DUF2407 ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.8   0.1   1.8e-05     0.032      14      68 ..      13      63 ..       7     126 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 1.8e-05
     DUF2407 14 leLdipdpntttvagLkqliRerlpaelasrrLrLIyaGrlLedttslasslklp 68
                ++L+++  ++ t+ ++k  i ++    +   + rLI+aG+ Led  +l++   ++
  EEA21687.1 13 ITLEVE--SSDTIDNVKSKIQDKE--GIPPDQQRLIFAGKQLEDGRTLSDYNIQK 63
                566666..6789999999999987..67777789**************9754443 PP

>> Sde2_N_Ubi  Silencing defective 2 N-terminal ubiquitin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   6.4e-05      0.11       2      88 ..       2      76 ..       1      77 [. 0.85

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 6.4e-05
  Sde2_N_Ubi  2 nvlvssfdgltlpstlsltlpstatvsdlvdklserlpeslkesliLttvsnkqlllssdvslssllassadsellslrllvrlrGG 88
                +++v+++ g+    t++l++ s+ t+ ++ +k++++      +   L  + + ql  ++  +ls++  ++++    +l+l++rlrGG
  EEA21687.1  2 QIFVKTLTGK----TITLEVESSDTIDNVKSKIQDKEGIPPDQ-QRLIFAGK-QL--EDGRTLSDYNIQKES----TLHLVLRLRGG 76
                8999*99996....999*****************998877555.45555554.66..99999****999999....99********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (128 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       791  (0.0441185); expected 358.6 (0.02)
Passed bias filter:                      454  (0.0253221); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.44u 0.23s 00:00:00.67 Elapsed: 00:00:00.40
# Mc/sec: 957.41
//
Query:       EEA21688.1  [L=300]
Description: Yip1 domain family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-14   54.5  13.3    1.8e-14   53.8  13.4    1.4  1  Yip1      Yip1 domain
  ------ inclusion threshold ------
      0.044   13.3   2.2      0.064   12.8   1.5    1.7  1  YIF1      YIF1


Domain annotation for each model (and alignments):
>> Yip1  Yip1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.8  13.4     2e-18   1.8e-14       1     144 [.      87     233 ..      87     276 .. 0.85

  Alignments for each domain:
  == domain 1  score: 53.8 bits;  conditional E-value: 2e-18
        Yip1   1 llldPrevfrrlkkepp........ilrapdlallllalltlllgllaslnlgqtlasg...eevqgltlssllgaiiggylglllgllllalllhlia 88 
                 + +d++ev rr  ++ +        +  +pdl++++++++t++ +l+++++++q+la +   +++++++l+s ++++i+gy g +++++l+++l ++  
  EEA21688.1  87 FDVDTNEVVRRCVAAVYprsnfldvLDGNPDLYGPFWIATTVVIILFLTGTISQYLAHEhdeHFEYDFRLLSGAAGLIYGYTG-VIPIALWGALRWF-- 182
                 6799******************************************************************************9.************9.. PP

        Yip1  89 kllg.gkgsfkqtlsvvgyallPlilgaliaillllllgtllllvgllaliWslvll 144
                    g ++ ++ ++++++gya l +i  al++  +l +l+   ++++ ++++W++++l
  EEA21688.1 183 ---GsSSADLIECWALYGYANLLWIAVALASWSPLTALN---WALVGVGFAWTVFFL 233
                 ...888899***********9999999999887666555...455666666666444 PP

>> YIF1  YIF1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   1.5   7.2e-06     0.064     145     209 ..     184     246 ..     110     271 .. 0.70

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 7.2e-06
        YIF1 145 ssasslldlvaysgYkfvgvivtlllklllgeglvyylvllylvlalafFllrsLklvllpease 209
                 ss++ l+++ a+ gY     i++ l++    +  ++++++ + ++ ++fFllr+L + +l+ +++
  EEA21688.1 184 SSSADLIECWALYGYANLLWIAVALASWSPLTA-LNWALVGVGFAWTVFFLLRNL-YPVLSATDA 246
                 3458999***************99999997777.9********************.555555443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (300 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       698  (0.0389313); expected 358.6 (0.02)
Passed bias filter:                      387  (0.0215851); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.24s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 2090.79
//
Query:       EEA21689.1  [L=407]
Description: TBC domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.8e-22   79.4   0.0      5e-22   78.6   0.0    1.4  1  RabGAP-TBC  Rab-GTPase-TBC domain


Domain annotation for each model (and alignments):
>> RabGAP-TBC  Rab-GTPase-TBC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.6   0.0   2.8e-26     5e-22       1     215 []      62     265 ..      62     265 .. 0.83

  Alignments for each domain:
  == domain 1  score: 78.6 bits;  conditional E-value: 2.8e-26
  RabGAP-TBC   1 delRgevWklllgyepevkrlkksekkqeksekeksklekseeskelsqIkkDvprtfp.es..esfknkqgqnqLeriLkaysiynpevgYcqGmndi 96 
                 d+lR+ +W+++lgy++          ++e+s +++ ++++ + ++++ qIk+Dv+r+f       +++ ++ ++qL+ ++     + p + Y+qG +di
  EEA21689.1  62 DTLRQAAWPIFLGYND----------EKEDSRQDRPDWKSLPRHEDEDQIKLDVNRSFVyYPqcGEEELDKRKQQLSDLITETLRRYPMLCYFQGYHDI 150
                 579***********65..........55666667777788888888*************62246677777999************************** PP

  RabGAP-TBC  97 vaplllvsldeeeaFwcfvsLlekyklrdlytsslpglkrklkvleellkkkdpklykhlkeegldlelfaikwfltlflrefpl.etvlrlwDllleg 194
                 +++lllv + +  a  +f++     ++rd++ +sl+   + l+++  +l+ +d ++ +hl     +  +fa+   ltl+++++   + ++rl+D+ll++
  EEA21689.1 151 AQVLLLVLGAQL-ARPAFARVS-LLRIRDYMLPSLSPALKHLQLIPAILEVTDTRIRRHLAG---TQPYFALAAALTLYAHDIEEyQDIVRLYDFLLAH 244
                 *****6666554.666666655.557*********9988899******************66...4558***********999755********88877 PP

  RabGAP-TBC 195 ekfvllrvalailklleeell 215
                 e +v +++ +ai+ + +eell
  EEA21689.1 245 EPVVAIYLFAAIILSRKEELL 265
                 778899988887777777775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (407 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       572  (0.0319036); expected 358.6 (0.02)
Passed bias filter:                      500  (0.0278878); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.48
# Mc/sec: 2550.23
//
Query:       EEA21690.1  [L=1951]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-79  262.9  19.1    1.9e-12   47.6   0.2   16.4 18  Ank_2     Ankyrin repeats (3 copies)
      1e-70  233.2  30.9    1.1e-06   29.1   0.0   22.9 24  Ank_4     Ankyrin repeats (many copies)
    4.1e-58  191.4  43.3    7.1e-07   29.4   0.0   22.1 22  Ank       Ankyrin repeat
    7.6e-58  191.8  34.1      5e-09   36.2   0.0   19.7 21  Ank_5     Ankyrin repeats (many copies)
    1.5e-47  154.0  38.7    1.5e-05   25.0   0.0   25.4 29  Ank_3     Ankyrin repeat
     0.0028   17.6   0.6      0.014   15.3   0.1    2.3  2  NACHT     NACHT domain


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.6   0.0   2.7e-15     8e-12       1      78 [.     482     570 ..     482     575 .. 0.87
   2 !   20.0   0.0   2.5e-07   0.00075      19      78 ..     587     645 ..     572     651 .. 0.84
   3 !    7.1   0.0    0.0028       8.3       9      50 ..     633     681 ..     625     692 .. 0.72
   4 !   15.4   0.0   7.2e-06     0.021      11      58 ..     714     771 ..     707     772 .. 0.80
   5 !    8.5   0.0     0.001         3      12      80 ..     786     870 ..     778     873 .. 0.75
   6 !   11.8   0.2   9.5e-05      0.29      19      81 ..     891     968 ..     879     972 .. 0.71
   7 !   11.4   0.0   0.00012      0.37      15      82 ..     959    1060 ..     943    1061 .. 0.69
   8 !   16.1   0.2   4.2e-06     0.012      24      75 ..    1026    1086 ..    1002    1094 .. 0.70
   9 !   47.6   0.2   6.3e-16   1.9e-12       2      83 .]    1037    1134 ..    1036    1134 .. 0.84
  10 !   32.8   0.0   2.7e-11     8e-08      19      67 ..    1099    1151 ..    1092    1155 .. 0.79
  11 !   12.6   0.4   5.4e-05      0.16      25      73 ..    1136    1203 ..    1132    1209 .. 0.76
  12 ?   -1.0   0.0      0.94   2.8e+03       4      43 ..    1223    1264 ..    1220    1278 .. 0.54
  13 !   36.9   0.0   1.4e-12   4.1e-09      25      82 ..    1411    1479 ..    1369    1480 .. 0.80
  14 !   16.5   0.0   3.2e-06    0.0096      25      80 ..    1482    1538 ..    1479    1540 .. 0.86
  15 !   10.9   0.0   0.00018      0.53       7      64 ..    1601    1667 ..    1586    1672 .. 0.73
  16 !   22.4   0.0   4.5e-08   0.00014      10      79 ..    1693    1776 ..    1684    1780 .. 0.73
  17 ?    2.4   0.0     0.079   2.3e+02      16      59 ..    1831    1890 ..    1826    1893 .. 0.56
  18 ?    4.4   0.0     0.019        56       9      72 ..    1863    1948 ..    1855    1951 .] 0.63

  Alignments for each domain:
  == domain 1  score: 45.6 bits;  conditional E-value: 2.7e-15
       Ank_2   1 LhlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlekgad 78 
                 Lh++a    ++  k L+ +g+d+n  + +++t+L  A+++g  ++v +Lleh       +d++g+ pLhyAa+ + +++vklLle g +
  EEA21690.1 482 LHVCAWGHITSYAKALIqSGHDCNalDgQKMTPLARAVIKGLPDMVAFLLEHganpnpdVDCNGKIPLHYAAERNDYQVVKLLLEAGGN 570
                 68888866457899***9*****9865899***********99********997777666699*********9999********98655 PP

  == domain 2  score: 20.0 bits;  conditional E-value: 2.5e-07
       Ank_2  19 gadpnkngktaLhyAakngnleivklLlehad.ndgrtpLhyAarsghleivklLlekgad 78 
                 g+dp+  +kt+L yA+++g +e v+++l+h++ +d + +L +++   +l+i+kl+++   d
  EEA21690.1 587 GYDPE-RHKTPLEYACQAGAVESVRAMLSHLTiEDLKLALCCSIMARQLKIIKLFINL-PD 645
                 56666.779*********************5557899*****************9943.34 PP

  == domain 3  score: 7.1 bits;  conditional E-value: 0.0028
       Ank_2   9 nlelvklLlegadpn...k.ngktaLhyAakngnleivklLleh...ad 50 
                 +l+++kl+++  d++   + + +  L++Aa+  + +i++l+l+     d
  EEA21690.1 633 QLKIIKLFINLPDIKvaeNkFTQKCLILAAETKDPQILRLFLDLvdtSD 681
                 345999999888887764269999*******999999999998533333 PP

  == domain 4  score: 15.4 bits;  conditional E-value: 7.2e-06
       Ank_2  11 elvklLl.egadpn.k..ngktaLhyAakngnleivklLleh......adndgrtpLh 58 
                 ++++l+l +g+d+n     g+taLh ++ +    +v  Lle       +d+ g+tpLh
  EEA21690.1 714 SCLDLILqNGCDVNaRgtIGQTALHECVTARAPSLVGKLLECgadvhaTDRIGNTPLH 771
                 578888899****9725699*****9999998899*9999845444566688*****9 PP

  == domain 5  score: 8.5 bits;  conditional E-value: 0.001
       Ank_2  12 lvklLl.egadpn....k.ngktaLhyAakngnl..ei.vklLleh......adndgrtpLhyAars..ghleivklLlekgadin 80 
                 +++ L+ +ga ++    +  g  +L + +k+ +l  ++ v lL  +       d++g+tp+h+ +r   g  e++k  +e gad+n
  EEA21690.1 786 ILHALMnSGAQLDvgniNeRGDAPLLAWCKRKSLinKFdVDLLRPYvkdwniSDSEGNTPIHLLVRAnvGK-ETLKKVVELGADPN 870
                 67778776655555444269999***999998654233789999877676666699*********996665.*******99**998 PP

  == domain 6  score: 11.8 bits;  conditional E-value: 9.5e-05
       Ank_2  19 gadpn..k.ngktaLhyAakngnl.eivklLleh......ad...ndgr.tpLhyAarsghleivk..lLlekgadinl 81 
                 g d++  + +g+ aLh+ ++n+ + e +++Ll++       +   ++ + t + yA ++++ ++v   +Ll + a++nl
  EEA21690.1 891 GPDLHatDyEGNGALHLLCENNRRtESLRMLLDAgvnpnhRNhrgDTLWhTFIRYALQWKSDNLVStvYLL-RRAEVNL 968
                 5566654368999*******9955599*****955444342244444445899999999888888877788.5577775 PP

  == domain 7  score: 11.4 bits;  conditional E-value: 0.00012
       Ank_2   15 lLlegadpn...k..ngktaLhyAakn..........gnlei.vklLleh............ad.......ndgrtpLhyAarsghleivklLlekg 76  
                  +Ll  a++n   k  +g+t Lh+ + +          g+++i  k Ll++            ++        +g+ p+h+Aa   ++ +v +L+ +g
  EEA21690.1  959 YLLRRAEVNlaaKnhEGQTLLHCMCGAdtlqpslapgGKRHIdTKKLLNAsnnpidrlpaveVNdmievedHQGQRPIHLAAA-CSEALVGWLIRRG 1054
                  4445666666552469**********95566666665555677899998445676677776622344455677*********6.5569******989 PP

       Ank_2   77 adinlk 82  
                  a ++ +
  EEA21690.1 1055 ATVTSR 1060
                  998865 PP

  == domain 8  score: 16.1 bits;  conditional E-value: 4.2e-06
       Ank_2   24 k....ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlek 75  
                  +    +g+ ++h+Aa    + +v +L+         + +gr+ Lh+Aa+ + ++ + l le+
  EEA21690.1 1026 EvedhQGQRPIHLAAACS-EALVGWLIRRgatvtsRTHQGRNLLHIAAEAKASNSIGLILEN 1086
                  133469******999986.3669****966666533399*********99988888888866 PP

  == domain 9  score: 47.6 bits;  conditional E-value: 6.3e-16
       Ank_2    2 hlAak.ngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh.............adndgrtpLhyAarsghleivklLlekgadin 80  
                  hlAa  ++   lv +L+  ga +   + +g++ Lh+Aa++   + + l+le+             ad+dgrtpLh+A+r g+le v lLle gad++
  EEA21690.1 1037 HLAAAcSE--ALVGWLIrRGATVTsrThQGRNLLHIAAEAKASNSIGLILENykheqqrkmavneADKDGRTPLHIACRAGRLESVILLLEAGADVT 1131
                  77777333..4******99988876526************99999*****94455778888866666*****************************9 PP

       Ank_2   81 lkd 83  
                  l d
  EEA21690.1 1132 LAD 1134
                  865 PP

  == domain 10  score: 32.8 bits;  conditional E-value: 2.7e-11
       Ank_2   19 gadpnkngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghle 67  
                  +ad  k+g+t+Lh+A+++g le v lLle+      ad++ +tpLh++a ++++ 
  EEA21690.1 1099 EAD--KDGRTPLHIACRAGRLESVILLLEAgadvtlADKERETPLHACAHFNRQH 1151
                  333..379***********99*******97766666779999******9888755 PP

  == domain 11  score: 12.6 bits;  conditional E-value: 5.4e-05
       Ank_2   25 ngktaLhyAakngnle.............ivklLleh.....ad.ndgrtpLhyAarsghleivklLl 73  
                  + +t+Lh++a+ +  +             i++lLle+     a+ n  rtpL +A+   + e++  L 
  EEA21690.1 1136 ERETPLHACAHFNRQHmvfddnetlrvteIIQLLLEKdadpvAEdNLHRTPLELAVLMANAEMAVTLA 1203
                  4689***999986545666677777776699****98855653368899*******987778877665 PP

  == domain 12  score: -1.0 bits;  conditional E-value: 0.94
       Ank_2    4 Aakngnle.lvklLl....egadpnkngktaLhyAakngnleivk 43  
                   a+n+n + lv+ L+    +g+ p+    + L + a+ngn e+++
  EEA21690.1 1223 TARNDNVDlLVDKLMktpsFGTTPD---FNHLLLMARNGNDEALR 1264
                  4555433225555554433334444...44555556666666654 PP

  == domain 13  score: 36.9 bits;  conditional E-value: 1.4e-12
       Ank_2   25 ngktaLh.yAakng..nleivklLleh......adndgrtpLhyAarsg..hleivklLlekgadinlk 82  
                   ++++Lh +A+ +   ++e++++Ll+h       d +grtpLh+A+  g  +lei+++Lle+gad+n+ 
  EEA21690.1 1411 PDRSVLHiLAVGEYwwQTEAIQYLLQHgadmamRDAEGRTPLHVAVTGGyrRLEIARVLLEHGADPNAL 1479
                  34899**66666557788********99676655599*********8764479*************985 PP

  == domain 14  score: 16.5 bits;  conditional E-value: 3.2e-06
       Ank_2   25 ngktaLhyAakngnleivklLleh...adndgrtpLhyAarsghleivklLlekgadin 80  
                  +g t+L +Aa++   e+v+lLl+h   ++   + +L+ A+  + +++v++ +e+g+di+
  EEA21690.1 1482 KGVTPLGFAAESP--EMVQLLLQHggkIELGSKPVLFEAITVQAIDTVRVIVESGFDIQ 1538
                  488********98..********9866554455669****99*************9996 PP

  == domain 15  score: 10.9 bits;  conditional E-value: 0.00018
       Ank_2    7 ngnlelvklLl.egadpn..k..ngktaLhyAakngnleivklLle..h.....adndgrtpLhyAarsg 64  
                  +++  +v+lLl +gadp   +  +  t++h   ++g   iv+ +l+  h      d  grt L++A+  g
  EEA21690.1 1601 HKAVAIVELLLaHGADPWlvSgdKTTTIIHDVLHQG--GIVEPFLAlsHlelekRDGLGRTLLMAACD-G 1667
                  345569*****9****9887345889****999999..9**87776555675544466********94.4 PP

  == domain 16  score: 22.4 bits;  conditional E-value: 4.5e-08
       Ank_2   10 lelvklLl.egadpn..k.ngktaLhyAakngnl...eivklLleh.......adndgrtpLhyAarsghleivklLlekgadi 79  
                   + v+ L   ga+++  + +gk++ h+ +  g+    e++  L+++        +++ +tpLh+Aa+  + ++v++Ll+ gad+
  EEA21690.1 1693 RHSVERLCeMGANISasDkTGKNVAHLLVATGQSlmkEVLPVLVAKfpdlvlqKNQQMETPLHLAAKDHQWDTVRILLDVGADP 1776
                  4688899877777777536*******888888532334456666657777764446677*******88889*******99*997 PP

  == domain 17  score: 2.4 bits;  conditional E-value: 0.079
       Ank_2   16 Ll.egadpn..k.ngktaLhyAakn....g..nleivklLleh......adndgrtpLhy 59  
                  Ll +g+d+n  + ng+t+++  +++    +  +  i   L+++       + +g++ Lh+
  EEA21690.1 1831 LLdQGVDINtrNdNGETPIFEYVRGlactQslHSPITDSLVAAgadilvRNHEGESLLHV 1890
                  666899999763699999997766511111112233444444354444333667777765 PP

  == domain 18  score: 4.4 bits;  conditional E-value: 0.019
       Ank_2    9 nlelvklLl.egadpn..k.ngktaLhyAakn.........gnlei.......vklLleh.....ad.ndgrtpLhyAarsghleivklL 72  
                  ++++ + L+ +gad+   + +g++ Lh+ ak          +   +         +L+e+     ++  + rtp  +Aa +g+ e +  L
  EEA21690.1 1863 HSPITDSLVaAGADILvrNhEGESLLHVVAKLpcnawfgkcQ---CkgefaepFMYLMEQgldpfQEdTKQRTPVDVAAAYGR-EGILAL 1948
                  445778888888887554359999999999963334442221...233334556899987855543356688***99999999.666555 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   1.2e-05     0.036      15      46 ..     492     522 ..     481     526 .. 0.85
   2 !   27.0   0.0   1.7e-09     5e-06       8      55 .]     518     565 ..     517     565 .. 0.84
   3 !    7.8   0.1    0.0017       5.2       3      27 ..     595     641 ..     593     674 .. 0.57
   4 !   11.0   0.0   0.00016      0.49      15      45 ..     714     743 ..     713     753 .. 0.84
   5 !    6.5   0.0    0.0042        13      20      40 ..     752     771 ..     745     772 .. 0.89
   6 !    5.7   0.0    0.0078        23      18      43 ..     826     850 ..     817     853 .. 0.76
   7 !    8.2   0.1    0.0012       3.7      17      47 ..     884     913 ..     882     914 .. 0.90
   8 !   17.9   0.5   1.2e-06    0.0036       2      40 ..     902     940 ..     901     951 .. 0.87
   9 ?    2.7   0.1     0.066     2e+02       7      41 ..     945     981 ..     939     985 .. 0.70
  10 !    7.5   0.1    0.0022       6.5       6      44 ..    1037    1073 ..    1032    1084 .. 0.86
  11 !   27.0   0.1   1.6e-09   4.8e-06       2      55 .]    1065    1124 ..    1064    1124 .. 0.88
  12 !   29.1   0.0   3.7e-10   1.1e-06       1      50 [.    1104    1152 ..    1104    1154 .. 0.93
  13 ?    4.6   0.0     0.017        52      14      51 ..    1163    1199 ..    1160    1203 .. 0.87
  14 ?   -0.2   0.0      0.55   1.7e+03      12      30 ..    1374    1393 ..    1363    1399 .. 0.83
  15 !   26.6   0.0   2.2e-09   6.6e-06       3      47 ..    1414    1460 ..    1413    1463 .. 0.89
  16 !   22.4   0.0   4.5e-08   0.00013      13      55 .]    1462    1501 ..    1460    1501 .. 0.92
  17 ?   -0.4   0.0      0.64   1.9e+03       5      28 ..    1515    1538 ..    1513    1541 .. 0.81
  18 !   11.3   0.0   0.00014      0.41       3      38 ..    1584    1627 ..    1583    1636 .. 0.80
  19 ?   -3.7   0.0         6   1.8e+04      29      43 ..    1652    1665 ..    1645    1669 .. 0.80
  20 ?   -2.9   0.0       3.8   1.1e+04      18      47 ..    1697    1725 ..    1695    1735 .. 0.78
  21 !   13.8   0.0   2.2e-05     0.067       3      44 ..    1752    1792 ..    1750    1800 .. 0.91
  22 !   10.5   0.0   0.00024      0.71      19      39 ..    1830    1849 ..    1829    1851 .. 0.93
  23 !    6.8   0.0    0.0036        11      17      43 ..    1867    1892 ..    1863    1905 .. 0.87
  24 ?   -1.0   0.0         1     3e+03      35      51 ..    1930    1946 ..    1914    1949 .. 0.54

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.2e-05
       Ank_4  15 elvrlLlekgadinaqdnrsGetalhiAakrg 46 
                  +++ L+++g d+na  +++ +t+l +A+ +g
  EEA21690.1 492 SYAKALIQSGHDCNAL-DGQKMTPLARAVIKG 522
                 459************9.***********9887 PP

  == domain 2  score: 27.0 bits;  conditional E-value: 1.7e-09
       Ank_4   8 aaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 a+i+g  ++v++Lle+ga++n   + +G  +lh+Aa r++++++klLl
  EEA21690.1 518 AVIKGLPDMVAFLLEHGANPNPDVDCNGKIPLHYAAERNDYQVVKLLL 565
                 66677779***********88832334889*****************8 PP

  == domain 3  score: 7.8 bits;  conditional E-value: 0.0017
       Ank_4   3 taLhyaaisgrlelvrlLlek.gad.....................i 27 
                 t+L ya+++g +e+vr  l++  ++                     i
  EEA21690.1 595 TPLEYACQAGAVESVRAMLSHlTIEdlklalccsimarqlkiiklfI 641
                 78999999999999999999833555555555555555555555552 PP

  == domain 4  score: 11.0 bits;  conditional E-value: 0.00016
       Ank_4  15 elvrlLlekgadinaqdnrsGetalhiAakr 45 
                  +++l+l++g d+na+    G+talh ++  
  EEA21690.1 714 SCLDLILQNGCDVNAR-GTIGQTALHECVTA 743
                 5899************.777******99965 PP

  == domain 5  score: 6.5 bits;  conditional E-value: 0.0042
       Ank_4  20 LlekgadinaqdnrsGetalh 40 
                 Lle gad++a+ +r G+t+lh
  EEA21690.1 752 LLECGADVHAT-DRIGNTPLH 771
                 77889******.********* PP

  == domain 6  score: 5.7 bits;  conditional E-value: 0.0078
       Ank_4  18 rlLlekgadinaqdnrsGetalhiAa 43 
                 +lL  + +d+n + +++G+t++h  +
  EEA21690.1 826 DLLRPYVKDWNIS-DSEGNTPIHLLV 850
                 4555556789**9.*********866 PP

  == domain 7  score: 8.2 bits;  conditional E-value: 0.0012
       Ank_4  17 vrlLlekgadinaqdnrsGetalhiAakrgn 47 
                 + ++le g+d++a+ + +G+ alh  + +++
  EEA21690.1 884 LSSWLELGPDLHAT-DYEGNGALHLLCENNR 913
                 56899*********.**********999875 PP

  == domain 8  score: 17.9 bits;  conditional E-value: 1.2e-06
       Ank_4   2 ltaLhyaai.sgrlelvrlLlekgadinaqdnrsGetalh 40 
                 ++aLh +++   r+e++r Ll+ g+++n++ n +G+t+ h
  EEA21690.1 902 NGALHLLCEnNRRTESLRMLLDAGVNPNHR-NHRGDTLWH 940
                 689***************************.*****9544 PP

  == domain 9  score: 2.7 bits;  conditional E-value: 0.066
       Ank_4   7 yaai..sgrlelvrlLlekgadinaq.dnrsGetalhi 41 
                 ya +  s +l +  +Ll ++a++n   +n +G+t+lh+
  EEA21690.1 945 YALQwkSDNLVSTVYLL-RRAEVNLAaKNHEGQTLLHC 981
                 55554444555556777.7888777778*********8 PP

  == domain 10  score: 7.5 bits;  conditional E-value: 0.0022
       Ank_4    6 hyaaisgrlelvrlLlekgadinaqdnrsGetalhiAak 44  
                  h +a+++ + lv +L+ +ga +  +   +G+++lhiAa 
  EEA21690.1 1037 H-LAAACSEALVGWLIRRGATVTSR-THQGRNLLHIAAE 1073
                  3.5569**********99*******.***********94 PP

  == domain 11  score: 27.0 bits;  conditional E-value: 1.6e-09
       Ank_4    2 ltaLhyaaisgrlelvrlLlek.gad......inaqdnrsGetalhiAakrgnveilklLl 55  
                  + +Lh aa++    ++ l+le+ + +      +n+  +++G+t+lhiA++ g++e ++lLl
  EEA21690.1 1065 RNLLHIAAEAKASNSIGLILENyKHEqqrkmaVNEA-DKDGRTPLHIACRAGRLESVILLL 1124
                  678******99999999999765666778888***8.**********************98 PP

  == domain 12  score: 29.1 bits;  conditional E-value: 3.7e-10
       Ank_4    1 eltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnvei 50  
                  ++t+Lh a+ +grle+v lLle gad+    +++ et+lh +a +++ ++
  EEA21690.1 1104 GRTPLHIACRAGRLESVILLLEAGADVTLA-DKERETPLHACAHFNRQHM 1152
                  589************************997.*************998666 PP

  == domain 13  score: 4.6 bits;  conditional E-value: 0.017
       Ank_4   14 lelvrlLlekgadinaqdnrsGetalhiAakrgnveil 51  
                  +e+++lLlek+ad+ a  ++ ++t+l  A+++ n e++
  EEA21690.1 1163 TEIIQLLLEKDADPVA-EDNLHRTPLELAVLMANAEMA 1199
                  6899*********877.4888***********999987 PP

  == domain 14  score: -0.2 bits;  conditional E-value: 0.55
       Ank_4   12 grlelvrlLlek.gadinaq 30  
                    +el+r+++e+ +ad+n +
  EEA21690.1 1374 PSMELLRIIVETfNADVNVR 1393
                  679********989****87 PP

  == domain 15  score: 26.6 bits;  conditional E-value: 2.2e-09
       Ank_4    3 taLhyaai...sgrlelvrlLlekgadinaqdnrsGetalhiAakrgn 47  
                  ++Lh +a      ++e++++Ll++gad  ++ +++G+t+lh A+ +g+
  EEA21690.1 1414 SVLHILAVgeyWWQTEAIQYLLQHGADMAMR-DAEGRTPLHVAVTGGY 1460
                  678888888888899****************.************9996 PP

  == domain 16  score: 22.4 bits;  conditional E-value: 4.5e-08
       Ank_4   13 rlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  rle++r Lle+gad+na  +  G t+l +A   +++e+++lLl
  EEA21690.1 1462 RLEIARVLLEHGADPNAL-DLKGVTPLGFA--AESPEMVQLLL 1501
                  89***************9.***********..78899999887 PP

  == domain 17  score: -0.4 bits;  conditional E-value: 0.64
       Ank_4    5 LhyaaisgrlelvrlLlekgadin 28  
                  L+ a+  + +++vr ++e+g di 
  EEA21690.1 1515 LFEAITVQAIDTVRVIVESGFDIQ 1538
                  6666666789************96 PP

  == domain 18  score: 11.3 bits;  conditional E-value: 0.00014
       Ank_4    3 taLhyaai.........sgrlelvrlLlekgadinaqdnrsGeta 38  
                  ++Lhyaa+         +  + +v+lLl++gad+  + +++  t 
  EEA21690.1 1584 RPLHYAAHrrfnkvaerHKAVAIVELLLAHGADPWLV-SGDKTTT 1627
                  58************666666666*************9.7766653 PP

  == domain 19  score: -3.7 bits;  conditional E-value: 6
       Ank_4   29 aqdnrsGetalhiAa 43  
                  ++ ++ G+t+l  A+
  EEA21690.1 1652 KR-DGLGRTLLMAAC 1665
                  67.888999999998 PP

  == domain 20  score: -2.9 bits;  conditional E-value: 3.8
       Ank_4   18 rlLlekgadinaqdnrsGetalhiAakrgn 47  
                  ++L e ga+i a+ ++ G +  h  + +g+
  EEA21690.1 1697 ERLCEMGANISAS-DKTGKNVAHLLVATGQ 1725
                  5667889999998.9999999998888776 PP

  == domain 21  score: 13.8 bits;  conditional E-value: 2.2e-05
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAak 44  
                  t+Lh aa++ + ++vr+Ll+ gad+    ++ G+t +h+ a+
  EEA21690.1 1752 TPLHLAAKDHQWDTVRILLDVGADPLTPEPK-GNTIFHYLAR 1792
                  89*****************99*******888.******9765 PP

  == domain 22  score: 10.5 bits;  conditional E-value: 0.00024
       Ank_4   19 lLlekgadinaqdnrsGetal 39  
                  +Ll++g+din + n++Get++
  EEA21690.1 1830 RLLDQGVDINTR-NDNGETPI 1849
                  599*********.******97 PP

  == domain 23  score: 6.8 bits;  conditional E-value: 0.0036
       Ank_4   17 vrlLlekgadinaqdnrsGetalhiAa 43  
                   ++L++ gadi  + n +Ge++lh +a
  EEA21690.1 1867 TDSLVAAGADILVR-NHEGESLLHVVA 1892
                  6799**********.*********987 PP

  == domain 24  score: -1.0 bits;  conditional E-value: 1
       Ank_4   35 GetalhiAakrgnveil 51  
                  ++t+++ Aa  g+  il
  EEA21690.1 1930 QRTPVDVAAAYGREGIL 1946
                  55666666655554444 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.9   0.1    0.0015       4.4       5      31 ..     481     508 ..     480     509 .. 0.91
   2 !   14.4   0.0   1.3e-05     0.039       3      28 ..     512     538 ..     511     542 .. 0.92
   3 !   19.7   0.0   2.8e-07   0.00084       1      30 [.     544     574 ..     544     576 .. 0.87
   4 ?    0.5   0.0      0.32   9.6e+02       4      22 ..     595     613 ..     593     645 .. 0.77
   5 ?   -0.5   0.0      0.69   2.1e+03       6      22 ..     658     674 ..     657     682 .. 0.84
   6 ?    1.0   0.0      0.22   6.6e+02      15      30 ..     713     729 ..     693     730 .. 0.81
   7 !   12.9   0.0     4e-05      0.12       2      31 ..     733     763 ..     732     764 .. 0.90
   8 !    6.4   0.1    0.0045        13       2      28 ..     766     798 ..     765     802 .. 0.68
   9 !    5.4   0.0     0.009        27       2      29 ..     842     871 ..     841     874 .. 0.69
  10 !    9.6   0.2   0.00044       1.3       2      31 ..     901     932 ..     900     933 .. 0.84
  11 ?   -1.1   0.0       1.1   3.2e+03       2      10 ..     975     983 ..     974    1012 .. 0.72
  12 ?    5.1   0.0     0.011        34       5      31 ..    1035    1061 ..    1031    1062 .. 0.82
  13 ?    1.0   0.0      0.23   6.9e+02       2      22 ..    1064    1084 ..    1063    1089 .. 0.73
  14 !   25.1   0.0   5.4e-09   1.6e-05       1      31 [.    1103    1134 ..    1103    1135 .. 0.92
  15 !   12.8   0.0   4.2e-05      0.13       4      32 .]    1139    1181 ..    1137    1181 .. 0.85
  16 !    7.9   0.0    0.0015       4.4       4      31 ..    1414    1445 ..    1412    1446 .. 0.76
  17 !   29.4   0.0   2.4e-10   7.1e-07       2      31 ..    1448    1480 ..    1447    1481 .. 0.94
  18 !    7.1   0.0    0.0028       8.2       2      24 ..    1483    1504 ..    1482    1510 .. 0.87
  19 !   14.7   0.2     1e-05     0.031       5      27 ..    1585    1617 ..    1585    1621 .. 0.84
  20 ?    2.5   0.1     0.075   2.2e+02       2      30 ..    1657    1709 ..    1656    1727 .. 0.54
  21 !   14.3   0.0   1.4e-05     0.042       4      27 ..    1752    1776 ..    1750    1779 .. 0.86
  22 ?   -2.6   0.0       3.2   9.5e+03      21      31 ..    1831    1842 ..    1823    1843 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0015
                 HHHHHHHHTT.HHHHHHHH.TTTSTTCBT CS
         Ank   5 PLHlAatngk.kriiklLL.hGAnlnald 31 
                 PLH++a  g+ ++ +k+L+ +G + nald
  EEA21690.1 481 PLHVCA-WGHiTSYAKALIqSGHDCNALD 508
                 9***88.7999999999**889*****98 PP

  == domain 2  score: 14.4 bits;  conditional E-value: 1.3e-05
                 BBHHHHHHHHTTHHHHHHHH.TTTSTT CS
         Ank   3 nTPLHlAatngkkriiklLL.hGAnln 28 
                 +TPL +A+  g ++++ +LL hGAn+n
  EEA21690.1 512 MTPLARAVIKGLPDMVAFLLeHGANPN 538
                 7*******7778**************9 PP

  == domain 3  score: 19.7 bits;  conditional E-value: 2.8e-07
                 TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCB CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hGAnlnal 30 
                 +G  PLH+Aa +++ +++klLL  G n+ ++
  EEA21690.1 544 NGKIPLHYAAERNDYQVVKLLLeAGGNPLIH 574
                 7999******99**********877798665 PP

  == domain 4  score: 0.5 bits;  conditional E-value: 0.32
                 BHHHHHHHHTTHHHHHHHH CS
         Ank   4 TPLHlAatngkkriiklLL 22 
                 TPL +A++ g ++ +++ L
  EEA21690.1 595 TPLEYACQAGAVESVRAML 613
                 9999999888777777776 PP

  == domain 5  score: -0.5 bits;  conditional E-value: 0.69
                 HHHHHHHTTHHHHHHHH CS
         Ank   6 LHlAatngkkriiklLL 22 
                 L lAa  ++++i++l+L
  EEA21690.1 658 LILAAETKDPQILRLFL 674
                 7899988********99 PP

  == domain 6  score: 1.0 bits;  conditional E-value: 0.22
                 HHHHHHHH.TTTSTTCB CS
         Ank  15 kriiklLL.hGAnlnal 30 
                 ++++ l+L +G+++na+
  EEA21690.1 713 TSCLDLILqNGCDVNAR 729
                 5688888877*****97 PP

  == domain 7  score: 12.9 bits;  conditional E-value: 4e-05
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlnald 31 
                 G T+LH ++t   ++ +  LL +GA+++a+d
  EEA21690.1 733 GQTALHECVTARAPSLVGKLLeCGADVHATD 763
                 99****989877799******99******99 PP

  == domain 8  score: 6.4 bits;  conditional E-value: 0.0045
                 SBBHHHHHH.........HHTTHHHHHHHH.TTTSTT CS
         Ank   2 GnTPLHlAa.........tngkkriiklLL.hGAnln 28 
                 GnTPLHl           ++    i+++L  +GA l+
  EEA21690.1 766 GNTPLHL-LdpdeqhsktSRP---ILHALMnSGAQLD 798
                 9******.5454444444455...8888887788776 PP

  == domain 9  score: 5.4 bits;  conditional E-value: 0.009
                 SBBHHHHHHHHTT......HHHHHHHHTTTSTTC CS
         Ank   2 GnTPLHlAatngk......kriiklLLhGAnlna 29 
                 GnTP Hl + +++      k +++ L  GA++n 
  EEA21690.1 842 GNTPIHLLV-RANvgketlKKVVE-L--GADPNW 871
                 9*****978.34445466666776.4..899985 PP

  == domain 10  score: 9.6 bits;  conditional E-value: 0.00044
                 SBBHHHHHHHHTT.HHHHHHHH.TTTSTTCBT CS
         Ank   2 GnTPLHlAatngk.kriiklLL.hGAnlnald 31 
                 Gn +LHl + n+  ++ +++LL  G n+n ++
  EEA21690.1 901 GNGALHLLCENNRrTESLRMLLdAGVNPNHRN 932
                 888***9895444899******66*****997 PP

  == domain 11  score: -1.1 bits;  conditional E-value: 1.1
                 SBBHHHHHH CS
         Ank   2 GnTPLHlAa 10 
                 G T LH+ +
  EEA21690.1 975 GQTLLHCMC 983
                 99****866 PP

  == domain 12  score: 5.1 bits;  conditional E-value: 0.011
                  HHHHHH..HHTTHHHHHHHH.TTTSTTCBT CS
         Ank    5 PLHlAa..tngkkriiklLL.hGAnlnald 31  
                  P HlAa  +++    + +L+ +GA +++++
  EEA21690.1 1035 PIHLAAacSEA---LVGWLIrRGATVTSRT 1061
                  99*99866777...******889*999876 PP

  == domain 13  score: 1.0 bits;  conditional E-value: 0.23
                  SBBHHHHHHHHTTHHHHHHHH CS
         Ank    2 GnTPLHlAatngkkriiklLL 22  
                  G+  LH+Aa  +  + i l+L
  EEA21690.1 1064 GRNLLHIAAEAKASNSIGLIL 1084
                  7889*****544466777665 PP

  == domain 14  score: 25.1 bits;  conditional E-value: 5.4e-09
                  TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    1 dGnTPLHlAatngkkriiklLL.hGAnlnald 31  
                  dG+TPLH+A++ g ++ + lLL  GA++++ d
  EEA21690.1 1103 DGRTPLHIACRAGRLESVILLLeAGADVTLAD 1134
                  8************999999***88****9877 PP

  == domain 15  score: 12.8 bits;  conditional E-value: 4.2e-05
                  BHHHHHHHHTT.............HHHHHHHH.TTTSTTCBTT CS
         Ank    4 TPLHlAatngk.............kriiklLL.hGAnlnaldn 32  
                  TPLH +a+++              ++ii+lLL + A++ a dn
  EEA21690.1 1139 TPLHACAHFNRqhmvfddnetlrvTEIIQLLLeKDADPVAEDN 1181
                  ****99966666699999999999********888**988876 PP

  == domain 16  score: 7.9 bits;  conditional E-value: 0.0015
                  BHHH.HHH.....HHTTHHHHHHHH.TTTSTTCBT CS
         Ank    4 TPLH.lAa.....tngkkriiklLL.hGAnlnald 31  
                  ++LH lA+     +   ++ i++LL hGA+ +++d
  EEA21690.1 1414 SVLHiLAVgeywwQ---TEAIQYLLqHGADMAMRD 1445
                  68996777554442...66******99***99988 PP

  == domain 17  score: 29.4 bits;  conditional E-value: 2.4e-10
                  SBBHHHHHHHHTT..HHHHHHHH.TTTSTTCBT CS
         Ank    2 GnTPLHlAatngk..kriiklLL.hGAnlnald 31  
                  G+TPLH+A+t+g   ++i++ LL hGA++nald
  EEA21690.1 1448 GRTPLHVAVTGGYrrLEIARVLLeHGADPNALD 1480
                  9********9888******************99 PP

  == domain 18  score: 7.1 bits;  conditional E-value: 0.0028
                  SBBHHHHHHHHTTHHHHHHHH.TT CS
         Ank    2 GnTPLHlAatngkkriiklLL.hG 24  
                  G TPL  Aa   ++++++lLL hG
  EEA21690.1 1483 GVTPLGFAA--ESPEMVQLLLqHG 1504
                  99*****99..7778******997 PP

  == domain 19  score: 14.7 bits;  conditional E-value: 1e-05
                  HHHHHH..HHTT.......HHHHHHHH.TTTST CS
         Ank    5 PLHlAa..tngk.......kriiklLL.hGAnl 27  
                  PLH+Aa  +++k       + i++lLL hGA++
  EEA21690.1 1585 PLHYAAhrRFNKvaerhkaVAIVELLLaHGADP 1617
                  9****9995555666667799**********98 PP

  == domain 20  score: 2.5 bits;  conditional E-value: 0.075
                  SBBHHHHHH.........HHTT................HHHHHHHH.TTTSTTCB CS
         Ank    2 GnTPLHlAa.........tngk................kriiklLL.hGAnlnal 30  
                  G+T L+ A+         +  +                 + ++ L   GAn+ a 
  EEA21690.1 1657 GRTLLMAACdgskkystgM--GqdfndpelhlsgsmqkRHSVERLCeMGANISAS 1709
                  8999999985444443330..0333333444444444433444444335555544 PP

  == domain 21  score: 14.3 bits;  conditional E-value: 1.4e-05
                  BHHHHHHHHTT.HHHHHHHHT.TTST CS
         Ank    4 TPLHlAatngk.kriiklLLh.GAnl 27  
                  TPLHlAa  ++ ++ ++ LL+ GA++
  EEA21690.1 1752 TPLHLAA-KDHqWDTVRILLDvGADP 1776
                  *******.577799******66**98 PP

  == domain 22  score: -2.6 bits;  conditional E-value: 3.2
                  HH.TTTSTTCBT CS
         Ank   21 LL.hGAnlnald 31  
                  LL +G ++n ++
  EEA21690.1 1831 LLdQGVDINTRN 1842
                  8988*****988 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.1   0.0   2.3e-08   6.8e-05       7      43 ..     502     538 ..     497     544 .. 0.92
   2 !   12.4   0.1   5.2e-05      0.16      19      44 ..     548     573 ..     538     577 .. 0.82
   3 !    8.1   0.0    0.0011       3.4      13      36 ..     591     613 ..     586     620 .. 0.84
   4 ?    2.3   0.0     0.073   2.2e+02      11      36 ..     649     674 ..     647     690 .. 0.82
   5 !   19.6   0.1   2.8e-07   0.00084       2      55 ..     720     772 ..     719     773 .. 0.97
   6 ?    4.4   0.0     0.017        51      10      25 ..     836     851 ..     832     879 .. 0.67
   7 !   19.7   0.8   2.6e-07   0.00079       3      54 ..     889     940 ..     888     942 .. 0.93
   8 ?   -2.0   0.0       1.7     5e+03      14      26 ..    1030    1042 ..    1026    1044 .. 0.80
   9 ?    2.6   0.1     0.061   1.8e+02      14      32 ..    1062    1080 ..    1050    1092 .. 0.72
  10 !   36.2   0.0   1.7e-12     5e-09       6      54 ..    1094    1142 ..    1089    1143 .. 0.92
  11 ?    3.9   0.0     0.023        68       1      35 [.    1169    1202 ..    1169    1208 .. 0.88
  12 !   11.5   0.0   9.6e-05      0.29      30      56 .]    1429    1455 ..    1427    1455 .. 0.94
  13 !   22.7   0.1     3e-08   8.9e-05       1      44 [.    1434    1478 ..    1434    1478 .. 0.89
  14 !   19.9   0.0   2.3e-07   0.00068       1      39 [.    1469    1504 ..    1469    1509 .. 0.94
  15 ?    1.5   0.2      0.14   4.1e+02      25      42 ..    1599    1617 ..    1579    1627 .. 0.68
  16 ?   -3.7   0.0       5.6   1.7e+04      12      24 ..    1653    1665 ..    1648    1667 .. 0.81
  17 ?   -1.3   0.0         1   3.1e+03      32      52 ..    1696    1716 ..    1695    1720 .. 0.85
  18 !   20.6   0.0   1.3e-07   0.00039       1      55 [.    1735    1789 ..    1735    1801 .. 0.90
  19 ?    3.9   0.0     0.024        73      35      52 ..    1831    1848 ..    1829    1849 .. 0.74
  20 ?    2.0   0.0     0.095   2.8e+02       1      25 [.    1870    1893 ..    1863    1900 .. 0.72
  21 ?   -0.9   0.0      0.73   2.2e+03      37      56 .]    1918    1937 ..    1914    1942 .. 0.61

  Alignments for each domain:
  == domain 1  score: 23.1 bits;  conditional E-value: 2.3e-08
       Ank_5   7 advnrldgggntpLhvAakygaadvvrlLlargadln 43 
                  d+n+ldg ++tpL  A+ +g +d+v +Ll++ga++n
  EEA21690.1 502 HDCNALDGQKMTPLARAVIKGLPDMVAFLLEHGANPN 538
                 59*******************************9987 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 5.2e-05
       Ank_5  19 pLhvAakygaadvvrlLlargadlnl 44 
                 pLh+Aa+++  +vv+lLl+ g ++ +
  EEA21690.1 548 PLHYAAERNDYQVVKLLLEAGGNPLI 573
                 9*****************88888765 PP

  == domain 3  score: 8.1 bits;  conditional E-value: 0.0011
       Ank_5  13 dgggntpLhvAakygaadvvrlLl 36 
                 ++++ tpL +A+ +ga + vr +l
  EEA21690.1 591 ERHK-TPLEYACQAGAVESVRAML 613
                 5566.****************999 PP

  == domain 4  score: 2.3 bits;  conditional E-value: 0.073
       Ank_5  11 rldgggntpLhvAakygaadvvrlLl 36 
                 +++++ + +L++Aa+   ++++rl+l
  EEA21690.1 649 AENKFTQKCLILAAETKDPQILRLFL 674
                 57888999*****************9 PP

  == domain 5  score: 19.6 bits;  conditional E-value: 2.8e-07
       Ank_5   2 lehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldl 55 
                 l++g +dvn++   g+t+Lh  + ++a+++v +Ll+ gad  +td  G+t+l+l
  EEA21690.1 720 LQNG-CDVNARGTIGQTALHECVTARAPSLVGKLLECGADVHATDRIGNTPLHL 772
                 8999.***********************************************97 PP

  == domain 6  score: 4.4 bits;  conditional E-value: 0.017
       Ank_5  10 nrldgggntpLhvAak 25 
                 n +d +gntp+h+ ++
  EEA21690.1 836 NISDSEGNTPIHLLVR 851
                 6677788888888777 PP

  == domain 7  score: 19.7 bits;  conditional E-value: 2.6e-07
       Ank_5   3 ehgpadvnrldgggntpLhvAak.ygaadvvrlLlargadlnltdsrGltald 54 
                 e g  d+ ++d +gn +Lh+ ++ +++ + +r+Ll+ g+++n ++ rG+t+++
  EEA21690.1 889 ELG-PDLHATDYEGNGALHLLCEnNRRTESLRMLLDAGVNPNHRNHRGDTLWH 940
                 556.8999******************************************986 PP

  == domain 8  score: -2.0 bits;  conditional E-value: 1.7
       Ank_5   14 gggntpLhvAaky 26  
                    g+ p+h+Aa +
  EEA21690.1 1030 HQGQRPIHLAAAC 1042
                  56889*****975 PP

  == domain 9  score: 2.6 bits;  conditional E-value: 0.061
       Ank_5   14 gggntpLhvAakygaadvv 32  
                    g + Lh+Aa++ a++ +
  EEA21690.1 1062 HQGRNLLHIAAEAKASNSI 1080
                  4566********9988765 PP

  == domain 10  score: 36.2 bits;  conditional E-value: 1.7e-12
       Ank_5    6 padvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltald 54  
                   ++vn  d++g tpLh+A+++g+++ v+lLl+ gad +l d++ +t+l+
  EEA21690.1 1094 KMAVNEADKDGRTPLHIACRAGRLESVILLLEAGADVTLADKERETPLH 1142
                  47888899***************************************96 PP

  == domain 11  score: 3.9 bits;  conditional E-value: 0.023
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlL 35  
                  Lle++ ad+ ++d+   tpL +A+   +a+++  L
  EEA21690.1 1169 LLEKD-ADPVAEDNLHRTPLELAVLMANAEMAVTL 1202
                  78998.******************98888888766 PP

  == domain 12  score: 11.5 bits;  conditional E-value: 9.6e-05
       Ank_5   30 dvvrlLlargadlnltdsrGltaldlA 56  
                  + +++Ll +gad  ++d++G+t+l++A
  EEA21690.1 1429 EAIQYLLQHGADMAMRDAEGRTPLHVA 1455
                  7889*********************98 PP

  == domain 13  score: 22.7 bits;  conditional E-value: 3e-08
       Ank_5    1 LlehgpadvnrldgggntpLhvAak..ygaadvvrlLlargadlnl 44  
                  Ll+hg ad   +d +g tpLhvA+   y++++++r+Ll++gad+n+
  EEA21690.1 1434 LLQHG-ADMAMRDAEGRTPLHVAVTggYRRLEIARVLLEHGADPNA 1478
                  89999.77777777788********9999**************995 PP

  == domain 14  score: 19.9 bits;  conditional E-value: 2.3e-07
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlarg 39  
                  Llehg ad+n+ld +g+tpL +Aa+  ++++v+lLl +g
  EEA21690.1 1469 LLEHG-ADPNALDLKGVTPLGFAAE--SPEMVQLLLQHG 1504
                  8****.*******************..*********887 PP

  == domain 15  score: 1.5 bits;  conditional E-value: 0.14
       Ank_5   25 k.ygaadvvrlLlargadl 42  
                  + + a  +v+lLla+gad+
  EEA21690.1 1599 ErHKAVAIVELLLAHGADP 1617
                  3355666777777777775 PP

  == domain 16  score: -3.7 bits;  conditional E-value: 5.6
       Ank_5   12 ldgggntpLhvAa 24  
                  +dg g t L+ A+
  EEA21690.1 1653 RDGLGRTLLMAAC 1665
                  688899****999 PP

  == domain 17  score: -1.3 bits;  conditional E-value: 1
       Ank_5   32 vrlLlargadlnltdsrGlta 52  
                  v++L+++ga++ + d+ G+++
  EEA21690.1 1696 VERLCEMGANISASDKTGKNV 1716
                  88999***********99765 PP

  == domain 18  score: 20.6 bits;  conditional E-value: 1.3e-07
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldl 55  
                  L++++p  v  +++  +tpLh+Aak + +d vr+Ll+ gad+ + +  G+t +++
  EEA21690.1 1735 LVAKFPDLVLQKNQQMETPLHLAAKDHQWDTVRILLDVGADPLTPEPKGNTIFHY 1789
                  56667777777788888*********************************99887 PP

  == domain 19  score: 3.9 bits;  conditional E-value: 0.024
       Ank_5   35 LlargadlnltdsrGlta 52  
                  Ll+ g+d+n+++++G+t+
  EEA21690.1 1831 LLDQGVDINTRNDNGETP 1848
                  667788888888888887 PP

  == domain 20  score: 2.0 bits;  conditional E-value: 0.095
       Ank_5    1 LlehgpadvnrldgggntpLhvAak 25  
                  L+++g ad+  ++ +g++ Lhv ak
  EEA21690.1 1870 LVAAG-ADILVRNHEGESLLHVVAK 1893
                  56777.7777777777788887777 PP

  == domain 21  score: -0.9 bits;  conditional E-value: 0.73
       Ank_5   37 argadlnltdsrGltaldlA 56  
                  + g+d+++ d   +t++d+A
  EEA21690.1 1918 EQGLDPFQEDTKQRTPVDVA 1937
                  55666666666666666665 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0     0.066     2e+02       5      31 .]     481     506 ..     479     506 .. 0.87
   2 !   15.3   0.0   6.9e-06     0.021       3      30 ..     512     538 ..     510     538 .. 0.95
   3 !   14.2   0.0   1.7e-05     0.049       5      29 ..     548     571 ..     544     573 .. 0.87
   4 ?    4.2   0.0     0.029        86       3      24 ..     594     615 ..     592     619 .. 0.87
   5 ?   -3.3   0.0         6   1.8e+04       5      23 ..     657     675 ..     655     676 .. 0.85
   6 ?    1.1   0.0      0.29   8.7e+02      17      31 .]     715     728 ..     709     728 .. 0.83
   7 !   11.9   0.0   8.8e-05      0.26       2      31 .]     733     761 ..     733     761 .. 0.96
   8 ?   -1.6   0.1       2.2   6.6e+03       2       8 ..     766     772 ..     766     773 .. 0.89
   9 !    7.9   0.0    0.0019       5.7       1      30 [.     841     870 ..     841     871 .. 0.92
  10 !   13.9   0.1   2.1e-05     0.063       1      31 []     900     930 ..     900     930 .. 0.91
  11 ?    2.2   0.0      0.13     4e+02       1      12 [.     974     985 ..     974     989 .. 0.85
  12 ?    3.6   0.0     0.046   1.4e+02       2      29 ..    1032    1057 ..    1031    1058 .. 0.88
  13 ?    3.3   0.0     0.056   1.7e+02       2      24 ..    1064    1086 ..    1063    1089 .. 0.80
  14 !   25.0   0.0   5.1e-09   1.5e-05       1      29 [.    1103    1130 ..    1103    1132 .. 0.94
  15 ?    1.5   0.2      0.22   6.5e+02       3      29 ..    1138    1176 ..    1136    1178 .. 0.53
  16 ?    0.7   0.0       0.4   1.2e+03       3      21 ..    1184    1202 ..    1182    1208 .. 0.83
  17 ?   -1.2   0.0       1.6   4.9e+03      15      31 .]    1376    1392 ..    1365    1392 .. 0.74
  18 ?    1.6   0.0       0.2     6e+02       4      28 ..    1414    1440 ..    1412    1441 .. 0.69
  19 !   18.7   0.0   5.6e-07    0.0017       1      31 []    1447    1478 ..    1447    1478 .. 0.92
  20 ?    3.8   0.0      0.04   1.2e+02       2      28 ..    1483    1506 ..    1482    1509 .. 0.79
  21 ?   -2.3   0.0       3.8   1.1e+04       6      29 ..    1515    1537 ..    1513    1538 .. 0.87
  22 ?    5.1   0.1     0.015        45       5      29 ..    1585    1617 ..    1584    1619 .. 0.74
  23 ?   -0.5   0.0         1     3e+03       2      10 ..    1657    1665 ..    1656    1668 .. 0.90
  24 !   11.8   0.0   9.7e-05      0.29       3      29 ..    1751    1776 ..    1749    1778 .. 0.94
  25 ?   -0.5   0.0      0.97   2.9e+03       2      12 ..    1783    1793 ..    1782    1798 .. 0.88
  26 ?   -2.9   0.0       5.8   1.7e+04      21      30 ..    1831    1839 ..    1828    1840 .. 0.85
  27 ?   -2.9   0.0         6   1.8e+04       1      29 [.    1844    1877 ..    1844    1878 .. 0.63
  28 ?   -0.6   0.0       1.1   3.3e+03       1      11 [.    1883    1893 ..    1883    1897 .. 0.85
  29 ?   -1.1   0.0       1.6   4.7e+03       2      21 ..    1930    1948 ..    1929    1951 .] 0.80

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.066
       Ank_3   5 pLhlAarsgnle.ivkfLlenkgadvna 31 
                 pLh ++  g+++ ++k+L++  g d+na
  EEA21690.1 481 PLH-VCAWGHITsYAKALIQ-SGHDCNA 506
                 566.9******88*******.8999985 PP

  == domain 2  score: 15.3 bits;  conditional E-value: 6.9e-06
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvn 30 
                 +tpL +A+  g +++v fLle +ga++n
  EEA21690.1 512 MTPLARAVIKGLPDMVAFLLE-HGANPN 538
                 7********************.9***98 PP

  == domain 3  score: 14.2 bits;  conditional E-value: 1.7e-05
       Ank_3   5 pLhlAarsgnleivkfLlenkgadv 29 
                 pLh+Aa+ +++ +vk+Lle  g ++
  EEA21690.1 548 PLHYAAERNDYQVVKLLLE-AGGNP 571
                 9******************.56655 PP

  == domain 4  score: 4.2 bits;  conditional E-value: 0.029
       Ank_3   3 etpLhlAarsgnleivkfLlen 24 
                  tpL +A+ +g +e v+++l +
  EEA21690.1 594 KTPLEYACQAGAVESVRAMLSH 615
                 69***********989999986 PP

  == domain 5  score: -3.3 bits;  conditional E-value: 6
       Ank_3   5 pLhlAarsgnleivkfLle 23 
                  L lAa+  ++ i++++l+
  EEA21690.1 657 CLILAAETKDPQILRLFLD 675
                 6889999999999999987 PP

  == domain 6  score: 1.1 bits;  conditional E-value: 0.29
       Ank_3  17 ivkfLlenkgadvna 31 
                  ++++l+ +g+dvna
  EEA21690.1 715 CLDLILQ-NGCDVNA 728
                 4899999.8****96 PP

  == domain 7  score: 11.9 bits;  conditional E-value: 8.8e-05
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvna 31 
                 G+t+Lh+++ +  +++v  Lle +gadv+a
  EEA21690.1 733 GQTALHECVTARAPSLVGKLLE-CGADVHA 761
                 89********************.****985 PP

  == domain 8  score: -1.6 bits;  conditional E-value: 2.2
       Ank_3   2 GetpLhl 8  
                 G+tpLhl
  EEA21690.1 766 GNTPLHL 772
                 8*****7 PP

  == domain 9  score: 7.9 bits;  conditional E-value: 0.0019
       Ank_3   1 nGetpLhlAarsgnle.ivkfLlenkgadvn 30 
                 +G+tp+hl +r++  +  +k  +e  gad+n
  EEA21690.1 841 EGNTPIHLLVRANVGKeTLKKVVE-LGADPN 870
                 69*************558******.9***99 PP

  == domain 10  score: 13.9 bits;  conditional E-value: 2.1e-05
       Ank_3   1 nGetpLhlAarsgnle.ivkfLlenkgadvna 31 
                 +G+ +Lhl +++++ +  +++Ll+  g+++n+
  EEA21690.1 900 EGNGALHLLCENNRRTeSLRMLLD-AGVNPNH 930
                 5899***********657******.9****96 PP

  == domain 11  score: 2.2 bits;  conditional E-value: 0.13
       Ank_3   1 nGetpLhlAars 12 
                 +G+t+Lh+ + +
  EEA21690.1 974 EGQTLLHCMCGA 985
                 69*******986 PP

  == domain 12  score: 3.6 bits;  conditional E-value: 0.046
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadv 29  
                  G+ p+hlAa +     v +L++ +ga v
  EEA21690.1 1032 GQRPIHLAAACSEAL-VGWLIR-RGATV 1057
                  8899**999999996.******.99976 PP

  == domain 13  score: 3.3 bits;  conditional E-value: 0.056
       Ank_3    2 GetpLhlAarsgnleivkfLlen 24  
                  G+++Lh+Aa++   + + ++len
  EEA21690.1 1064 GRNLLHIAAEAKASNSIGLILEN 1086
                  99********9988667777775 PP

  == domain 14  score: 25.0 bits;  conditional E-value: 5.1e-09
       Ank_3    1 nGetpLhlAarsgnleivkfLlenkgadv 29  
                  +G+tpLh+A+r+g+le v++Lle  gadv
  EEA21690.1 1103 DGRTPLHIACRAGRLESVILLLE-AGADV 1130
                  69*************99******.8***8 PP

  == domain 15  score: 1.5 bits;  conditional E-value: 0.22
       Ank_3    3 etpLhlAarsgnl.............eivkfLlenkgadv 29  
                  etpLh +a++++              ei+++Lle k ad+
  EEA21690.1 1138 ETPLHACAHFNRQhmvfddnetlrvtEIIQLLLE-KDADP 1176
                  6777766555554333333333333235778887.77776 PP

  == domain 16  score: 0.7 bits;  conditional E-value: 0.4
       Ank_3    3 etpLhlAarsgnleivkfL 21  
                  +tpL lA++ +n e++  L
  EEA21690.1 1184 RTPLELAVLMANAEMAVTL 1202
                  8**********99986555 PP

  == domain 17  score: -1.2 bits;  conditional E-value: 1.6
       Ank_3   15 leivkfLlenkgadvna 31  
                   e+++ ++e ++advn+
  EEA21690.1 1376 MELLRIIVETFNADVNV 1392
                  35799**********95 PP

  == domain 18  score: 1.6 bits;  conditional E-value: 0.2
       Ank_3    4 tpLhlAarsgnl...eivkfLlenkgad 28  
                  + Lh+ a        e +++Ll+ +gad
  EEA21690.1 1414 SVLHILAVGEYWwqtEAIQYLLQ-HGAD 1440
                  55665555555555458******.8*98 PP

  == domain 19  score: 18.7 bits;  conditional E-value: 5.6e-07
       Ank_3    1 nGetpLhlAarsgnl..eivkfLlenkgadvna 31  
                  +G+tpLh+A+  g    ei++ Lle +gad+na
  EEA21690.1 1447 EGRTPLHVAVTGGYRrlEIARVLLE-HGADPNA 1478
                  69*************6669******.9****96 PP

  == domain 20  score: 3.8 bits;  conditional E-value: 0.04
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgad 28  
                  G tpL +Aa+s     v++Ll+ +g  
  EEA21690.1 1483 GVTPLGFAAESPEM--VQLLLQ-HGGK 1506
                  67888888888887..******.6765 PP

  == domain 21  score: -2.3 bits;  conditional E-value: 3.8
       Ank_3    6 LhlAarsgnleivkfLlenkgadv 29  
                  L++A+  + ++ v+ ++e  g d+
  EEA21690.1 1515 LFEAITVQAIDTVRVIVE-SGFDI 1537
                  889999999999******.89987 PP

  == domain 22  score: 5.1 bits;  conditional E-value: 0.015
       Ank_3    5 pLhlAarsgnlei.........vkfLlenkgadv 29  
                  pLh+Aa+    ++         v++Ll  +gad+
  EEA21690.1 1585 PLHYAAHRRFNKVaerhkavaiVELLLA-HGADP 1617
                  8999999999944444455555******.9**98 PP

  == domain 23  score: -0.5 bits;  conditional E-value: 1
       Ank_3    2 GetpLhlAa 10  
                  G+t+L+ A+
  EEA21690.1 1657 GRTLLMAAC 1665
                  9*******9 PP

  == domain 24  score: 11.8 bits;  conditional E-value: 9.7e-05
       Ank_3    3 etpLhlAarsgnleivkfLlenkgadv 29  
                  etpLhlAa+    + v+ Ll+  gad+
  EEA21690.1 1751 ETPLHLAAKDHQWDTVRILLD-VGADP 1776
                  7********************.8**98 PP

  == domain 25  score: -0.5 bits;  conditional E-value: 0.97
       Ank_3    2 GetpLhlAars 12  
                  G+t++h+ ar+
  EEA21690.1 1783 GNTIFHYLARC 1793
                  9******9986 PP

  == domain 26  score: -2.9 bits;  conditional E-value: 5.8
       Ank_3   21 Llenkgadvn 30  
                  Ll+  g+d+n
  EEA21690.1 1831 LLD-QGVDIN 1839
                  999.9****9 PP

  == domain 27  score: -2.9 bits;  conditional E-value: 6
       Ank_3    1 nGetpLh.....lAarsgnle.ivkfLlenkgadv 29  
                  nGetp++     lA+ +  ++ i + L+   gad+
  EEA21690.1 1844 NGETPIFeyvrgLACTQSLHSpITDSLVA-AGADI 1877
                  68888885555566666666556677777.66665 PP

  == domain 28  score: -0.6 bits;  conditional E-value: 1.1
       Ank_3    1 nGetpLhlAar 11  
                  +Ge++Lh++a+
  EEA21690.1 1883 EGESLLHVVAK 1893
                  59******996 PP

  == domain 29  score: -1.1 bits;  conditional E-value: 1.6
       Ank_3    2 GetpLhlAarsgnleivkfL 21  
                  ++tp  +Aa +g+   + +L
  EEA21690.1 1930 QRTPVDVAAAYGREG-ILAL 1948
                  69**********987.5555 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.1   4.8e-06     0.014       3      84 ..      71     165 ..      69     179 .. 0.80
   2 ?   -0.9   0.1      0.44   1.3e+03      72     151 ..    1188    1280 ..    1138    1283 .. 0.64

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 4.8e-06
                 EEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-................-HCHHHCCCCTS--SSS-C.CHHHHCCSCCCEE CS
       NACHT   3 vilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgna.............rsladllfsqlpepaapvse.vwavllelperlL 84 
                 ++++  aG GK++L ++ +++++++++++  + ++F+ ++ + ++++ a             +sl+ +l +  ++ +++++e ++a+l+++ + +L
  EEA21690.1  71 LWIKAIAGAGKSVLTASWISQLQQNEPQAI-VLFSFVRQVVTANHESHAlirdwldqllphsPSLQAVLIARRKKTSSAITEiGFAELWRILTDAL 165
                 677778********************7776.8*************999977777777777777777777777777777777776666666666655 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.44
                  CHHHHCCSCCCEEEEEE-STT-SS-TCH.................HHHHHC....TTTTT--EEEEEEECCCHHHHCTTSSCE...EEEE--T CS
       NACHT   72 vwavllelperlLlilDglDelvtdlgq........kekqpvrtlLselir....kkllpeasllltvrpralrdleeqleea.ivlevegfs 151 
                    avl++++e ++ + D +  +++++++        +++ +v+ l  +l++    ++ +  ++lll +r+++ + l+ +l+++  +  +++f+
  EEA21690.1 1188 ELAVLMANAEMAVTLADTFPSTPQQPRPsaaqlyltARNDNVDLLVDKLMKtpsfGTTPDFNHLLLMARNGNDEALRIKLQKTpPYWTIRDFE 1280
                  566666666666666676666666666677777776555555555555554111146678899999999999999999999887777777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1951 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       407  (0.0227007); expected 358.6 (0.02)
Passed bias filter:                      391  (0.0218082); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.06u 0.29s 00:00:01.35 Elapsed: 00:00:00.50
# Mc/sec: 11749.21
//
Query:       EEA21691.1  [L=488]
Description: hydantoin utilization protein C, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.7e-32  112.8   0.1      3e-32  112.0   0.1    1.4  1  Peptidase_M20  Peptidase family M20/M25/M40
    7.8e-05   22.6   0.0    0.00021   21.2   0.0    1.7  1  M20_dimer      Peptidase dimerisation domain
     0.0002   21.1   0.0    0.00035   20.3   0.0    1.4  1  Peptidase_M28  Peptidase family M28
  ------ inclusion threshold ------
      0.023   14.2   0.5      0.041   13.3   0.5    1.3  1  DUF4735        Domain of unknown function (DUF4735)


Domain annotation for each model (and alignments):
>> Peptidase_M20  Peptidase family M20/M25/M40
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.0   0.1   6.8e-36     3e-32       1     204 [.     127     473 ..     127     476 .. 0.91

  Alignments for each domain:
  == domain 1  score: 112.0 bits;  conditional E-value: 6.8e-36
                    EEEEES-BSSTTCGGGSSSTTSEEETTTEEESTTTTTTHHHHHHHHHHHHHHHHHTTT-SSEEEEEEESTTSSTT.......THH.HHHHH..HHH CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxx.xxxxx..xxx RF
  Peptidase_M20   1 llgsHlDvVpeeetdgwttpfslteedGklyGrGaddmkggvlaalealralkdegikpkgtivllfqpdEEggr.......gGa.kalle..gle 86 
                    ++gsHlD++p    +g           G+++G        gvlaalealr+++++g++++g+i l+++++EEg+r       +G  + ++      
     EEA21691.1 127 MMGSHLDTQP----TG-----------GRYDGI------LGVLAALEALRTIHESGYQTEGPIGLINWTNEEGARfpmvtvsSGVwADVVPleT-- 199
                    689*******....67...........999999......*********************************9998888854444444444540.. PP

                    T....................................TTCESEEEEEEEESSSBTCHSTETEEEE............................... CS
                    x....................................xxxxxxxxxxxxxxxxxxxxxxxxxxxx............................... RF
  Peptidase_M20  87 e....................................rekvdavfelhieepgileagklaigvv............................... 115
                                                         + ++ a felhie+++ile+++ +igvv                               
     EEA21691.1 200 AwncrevaslsqgpelktmkqelarigflgeipasykALPIGAHFELHIEQGPILENEEQKIGVVtagqayswfeitvkgqdchagttplsarrdp 295
                    155557788888899999999999************99********************************************************** PP

                    ............................................................................EEEEEEEEEESHEEEC.CHH CS
                    ............................................................................xxxxxxxxxxxxxxxx.xxx RF
  Peptidase_M20 116 ............................................................................kvevelleggapvtln.dsp 134
                                                                                                 vev+++   + v+++ +++
     EEA21691.1 296 llaaakmiaasnqiaktssglittgilqampgsintmahtvkftmdirhpqdeqvsnmveqccqafdeiatedserGVEVSWETLTENVAVKfHPD 391
                    ***************************************************************************7599999988888888888** PP

                    HHHHHHHHHHHHH.T.........SC.EEEEEESSSBHTHHHH.TTTEEEEEEESS.GGCTTSTTTEEEHHHHHHHHHHHHHH CS
                    xxxxxxxxxxxxx.x.........xx.xxxxxxxxxxxxxxxx.xxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_M20 135 lvkalaeaaeelf.g.........ek.velivsgpggtdarff.agiptvmifgpg.sglaHspnEyvdledlekgikvlarl 204
                    +++a+++aae+++           ++ ++ ++sg +g+d++ + ++ pt+mif p  +g++H+p+Ey+++ed++ g++vl  +
     EEA21691.1 392 CIAAVESAAEAVCaSvpanqnpsnKSlWRHMTSG-AGHDSCNVsKRCPTAMIFTPTrNGMSHTPEEYCSPEDCVLGAEVLMGA 473
                    ************9735677888865589999***.********6666*******8856*********************9865 PP

>> M20_dimer  Peptidase dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.0   4.6e-08   0.00021       6     104 ..     270     364 ..     266     371 .. 0.80

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 4.6e-08
                 EEEEEEEEE-B-EEGG.-TTTTB-.HHHHHHHHHHCSCTTEEC.....TCCTCCCCCEECCE-C.CCCEESSEEEEEEEEEHHHHHHHHHHHHHHHHHH CS
   M20_dimer   6 laggkitvkgkagHsg.apgagaN.AieklarllaeledeegdiaeerslprttlnvtgiegGs.aknvipdeaeakidiRllpgedpeevleeieeil 101
                 + +++itvkg+++H+g  p  ++  ++ ++a+++a+ ++  +        +   ++ +++++   ++n+ + ++++++diR ++ e++    e+  +++
  EEA21691.1 270 YSWFEITVKGQDCHAGtTPLSARRdPLLAAAKMIAASNQIAKT-------SSGLITTGILQAMPgSINTMAHTVKFTMDIRHPQDEQVSNMVEQCCQAF 361
                 579*************999887666999999999999999443.......44667777777777*****************999998777666665555 PP

                 TSC CS
   M20_dimer 102 eke 104
                 ++ 
  EEA21691.1 362 DEI 364
                 554 PP

>> Peptidase_M28  Peptidase family M28
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0   7.8e-08   0.00035       1      73 [.     111     178 ..     111     193 .. 0.89

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 7.8e-08
                    EEEEEESTTCE.SEEEEEEEE--B-TTTTCCT---TTTTHHHHHHHHHHHHHCHHGGCCSSEEEEEEEESSCSG CS
  Peptidase_M28   1 Nviatlegkat.devlllgAHyDsvgvgrgpifvGAdDnAsgvaalLelarvlaasgsrpkrgvrflffdaEEa 73 
                    N+ a  +g+++ +  +++g+H+D+ ++       G  D   gv a Le +r++ +sg + +  + ++ ++ EE 
     EEA21691.1 111 NIFAVRPGRNKtAPPVMMGSHLDTQPT---G---GRYDGILGVLAALEALRTIHESGYQTEGPIGLINWTNEEG 178
                    78888888888566************8...4...6789999*******************************95 PP

>> DUF4735  Domain of unknown function (DUF4735)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.5   9.2e-06     0.041      32     133 ..     348     446 ..     321     452 .. 0.66

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 9.2e-06
     DUF4735  32 drikqlskkaselidkalpylaksdpeyyeefsklvskpwklpkrlr..kldeslilsekepvks......fseekSdkClaellgsskkkskpCtvsd 122
                 +++++             +  +  d+   e+ ++ v+ +w+   +    k+ ++ i   +++++        +++ S+k l++ + s++ + ++C+vs+
  EEA21691.1 348 EQVSN----------MVEQCCQAFDEIATEDSERGVEVSWETLTENVavKFHPDCIAAVESAAEAvcasvpANQNPSNKSLWRHMTSGAGH-DSCNVSK 435
                 44444..........444455555555556666666666655555544455555555555544445566899*************999887.8****** PP

     DUF4735 123 eCwklmtqpgl 133
                 +C + m  + +
  EEA21691.1 436 RCPTAMIFTPT 446
                 **988876555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (488 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       505  (0.0281667); expected 358.6 (0.02)
Passed bias filter:                      437  (0.0243739); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.64u 0.36s 00:00:01.00 Elapsed: 00:00:00.57
# Mc/sec: 2563.11
//
Query:       EEA21692.1  [L=476]
Description: aldehyde dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   5.2e-142  473.6   0.0   6.4e-142  473.3   0.0    1.0  1  Aldedh    Aldehyde dehydrogenase family
  ------ inclusion threshold ------
       0.12   11.8   0.0        0.2   11.1   0.0    1.3  1  DUF1487   Protein of unknown function (DUF1487)


Domain annotation for each model (and alignments):
>> Aldedh  Aldehyde dehydrogenase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  473.3   0.0  7.1e-146  6.4e-142      11     460 ..      26     468 ..      20     470 .. 0.97

  Alignments for each domain:
  == domain 1  score: 473.3 bits;  conditional E-value: 7.1e-146
                 EEETTTCEEEEEEE-B-HHHHHHHHHHHHHHHHHHTTS-HHHHHHHHHHHHHHHHHTHHHHHHHHHHHH---HHHHHHHHHHHHHHHHHHHHHHHHHSE CS
      Aldedh  11 vinPatgeviakvpaataedvdaavaaAkeafkawaklpaeeRaeiLrkaadlleerkeelaeletletGkplaearaeveeaidvlryyaelaekleg 109
                  inPatge+   vp +t++dv+ a+aaAk+a  +w k+p+eeR+++L ++ +++e++++e+a l+t+e+Gkpl+ a  ev++a+++++ + e   +l++
  EEA21692.1  26 AINPATGEPNEPVPISTPDDVEMAMAAAKKASISWGKVPFEERRRCLLEFSKAIESHRDEFASLLTREQGKPLSLAGIEVTSALRWFQAFSEC--DLKD 122
                 69*******************************************************************************876666666554..3666 PP

                 EEEEECTTEEEEEEEEE-SEEEEEE-SSSCCHHHHHHHHHHHHTT-EEEEEE-TTSHHHHHHHHHHHHHTTS-TTSEEE--SSTCCHHHHHHH-TTESE CS
      Aldedh 110 evlpssegklalvrrePlGvvgaItPWNfPlllaawklapalaaGNtvvlKPaeetplsalllaelfeeaglPkgvlnvvtgsgsevgealvehpevdk 208
                 ++++ +e+++++ r+ PlGv + I+PWNfP++la+ kl pa++aGN +++KP++ tp ++l+l el+++  +P+gv++ ++g ++ +g  l++hp  +k
  EEA21692.1 123 TIIKDDEHRKIVCRYTPLGVAVGIIPWNFPFALACAKLGPAVLAGNPMIMKPSPFTPYTCLKLSELAQD-FFPPGVVQALSG-DDRLGPWLTSHPIPEK 219
                 7777799**************************************************************.8***********.778************* PP

                 EEEES-HHHHHHHHHHHHCTTSEEEEEE---EEEEE-TTSHHHHHHHHHHHHHHGGGGTSTTSEEEEEEEHHHHHHHHHHHHHHHHT--BS-TTSTT-S CS
      Aldedh 209 vsftGstevgrkiakaaaknlkrvtlElGGknplivledaDldkaveaivkgafgnaGQvCiaasrllvqesiydefveklveaakklkvgdpldedtd 307
                 +sftGst +g+k+++aaa+++krvtlElGG++p+iv++d+D++++++++++ +f+n+GQ+C a++r++v+esi+d+f+e++v+++k+lkvg++ +e + 
  EEA21692.1 220 ISFTGSTVTGKKVMEAAAGTMKRVTLELGGNDPAIVCADVDIEQTAKKVANLSFLNSGQICLAIKRIYVHESIHDQFLEAMVNHVKTLKVGEGNEEGVF 318
                 *************************************************************************************************** PP

                 B---SSHHHHHHHHHHHHHHHHTTSEEEE-TTE.SB-SSSTTEE--EEEES-TTTSHHHHS---SSEEEEEEESSHHHHHHHHHSSSEESEEEEE-SBH CS
      Aldedh 308 vGPliseaqlekvekyveeakeegaklllGgereeaglekgyfvePtvlanvtpdmriaqeEiFGPVlsvikfkdeeeaieiaNdteyGLaagvftkdl 406
                 +GP+ +  q+e+v++++e++k+e++++ + +   + +++ gyf++Pt+++   +d+ri++eE FGP++++++   e+++i+ aNdt++GL+a+v+++dl
  EEA21692.1 319 MGPIQNCMQYERVKGFLETGKAENWTIATPS--PTVNDRPGYFINPTIIDRPADDSRIVTEEPFGPIVPLLTWTHEDDVIRRANDTRMGLGASVWSRDL 415
                 *****************************99..67899************************************************************* PP

                 HHHHHHHHHS-SSEEEESSSST--TTTSEB--CGGGEES-BSHHHHHHHTEEEE CS
      Aldedh 407 eraervaerleaGnvyiNdsttgaaealpfgGvkqSglGreggkegleeytevk 460
                 e+a r++++leaG+v+iN++ + +++  p+gG+k+Sg+G e g  gl ++++++
  EEA21692.1 416 EQAGRISQSLEAGTVWINNHFDLDPSV-PYGGHKESGMGLELGMSGLLAFCNTQ 468
                 *************************99.***********************987 PP

>> DUF1487  Protein of unknown function (DUF1487)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   2.2e-05       0.2       9      61 ..     254     308 ..     250     340 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 2.2e-05
     DUF1487   9 vifedgDlnsalealve..slkePfaegavatvlveesirdefvervrsklkpls 61 
                 ++++d D+++ ++++++   l+    + a+  + v+esi d+f+e + +++k l+
  EEA21692.1 254 IVCADVDIEQTAKKVANlsFLNSGQICLAIKRIYVHESIHDQFLEAMVNHVKTLK 308
                 89*********999965216888999999******************99999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (476 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       340  (0.0189637); expected 358.6 (0.02)
Passed bias filter:                      338  (0.0188521); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.33s 00:00:00.95 Elapsed: 00:00:00.53
# Mc/sec: 2703.06
//
Query:       EEA21693.1  [L=366]
Description: alcohol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      3e-24   85.0   0.2    5.6e-24   84.1   0.2    1.5  1  ADH_N         Alcohol dehydrogenase GroES-like domain
    2.7e-21   75.9   0.6    3.9e-21   75.4   0.6    1.2  1  ADH_zinc_N    Zinc-binding dehydrogenase
     0.0008   20.5   0.2     0.0021   19.1   0.1    1.7  2  ADH_zinc_N_2  Zinc-binding dehydrogenase
      0.002   17.6   0.2     0.0032   17.0   0.2    1.2  1  Glu_dehyd_C   Glucose dehydrogenase C-terminus
  ------ inclusion threshold ------
      0.055   12.9   0.2       0.13   11.7   0.2    1.7  1  adh_short     short chain dehydrogenase
       0.18   11.2   1.3       0.44    9.9   0.1    1.9  2  SAM_MT        Putative SAM-dependent methyltransferase


Domain annotation for each model (and alignments):
>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.1   0.2   1.9e-27   5.6e-24       2     108 ..      37     149 ..      36     150 .. 0.93

  Alignments for each domain:
  == domain 1  score: 84.1 bits;  conditional E-value: 1.9e-27
                 TEEEEEEEEEEE-HHHHHHHTTS...TTTTSSSSEE---EEEEEEEEESTT-CS..--TT-EEEE-SEEE.-SSSHHHHTT-GGG-TTBEETTTSS-SS CS
       ADH_N   2 gevlikvkaagiCgsDlhilkgg...kelevklplilGHEivGeveevgpevkk..lkvGdrVvveplis.cgeCaaCkegeenlCeeakllgvsldGg 94 
                 g+vl++++ +g+C+sDl ++  +     ++++++++ GHE +G+++e+gp++++  lk+GdrV ++++   cg+C+ C +g++ +C ++k+ g++++G+
  EEA21693.1  37 GDVLVQMTHSGVCRSDLSVMMRRwsyLGPPTQAGQVGGHEGIGIIAELGPGTESskLKIGDRVGIKWMARvCGNCRPCLSGRDGCCLKGKISGYEVPGS 135
                 68***************99988756666788999***************9998778***********9999**************************** PP

                 SBSEEEECGGGEEE CS
       ADH_N  95 faeyvvvpekklvk 108
                 f++  ++p++++ +
  EEA21693.1 136 FQQFALAPANYVTP 149
                 *********99987 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.4   0.6   1.3e-24   3.9e-21       1     128 [.     192     327 ..     192     329 .. 0.90

  Alignments for each domain:
  == domain 1  score: 75.4 bits;  conditional E-value: 1.3e-24
                 HHHHHHHHH.HHHTT-EEEEEESSHHHHHHHHHTTESEEEET.....TTCHHHHHHHHHTT.TSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSCTS CS
  ADH_zinc_N   1 gvGlaavql.AkalGaeviavdsseeklelakklGadeviny.....keadlverikeltg.gegvdvvfecvGsgatleaalkllkpgGrlvvvGggk 92 
                 g+G++a+q+ A+ +G e i+vd  + k  +ak+ Ga+ +++      +e dlv++ike t  g g+ +v+ c++s++++ aalk+l+  G+lv+vG+++
  EEA21693.1 192 GLGHLALQMgANGMGYEMIGVDYGD-KGNFAKECGANTFFDVtkyasNE-DLVKAIKESTPdGLGAAAVIVCTASNEAYAAALKVLRFAGTLVCVGVPE 288
                 89******8466************9.69**************9997444.9*********669**********************************99 PP

                 SEEE....EEHHHHHHTT-EEEEE-SSCHHHHHHHHHHHH CS
  ADH_zinc_N  93 geee....fdlrnlllkeksilGsllgslreefkealdll 128
                 g+++     d++ l+ ke++i+Gsl+g+ r++  e l l+
  EEA21693.1 289 GKQVpiatADPASLISKEIRIVGSLVGN-RQDAIETLSLA 327
                 9888888888888***************.77777777665 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       2.3   6.9e+03      32      63 ..     166     195 ..     157     213 .. 0.61
   2 !   19.1   0.1   6.9e-07    0.0021      21     133 .]     254     362 ..     224     362 .. 0.72

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 2.3
                   HHHH.HHHHHHE.EEEEEEEE----.S-EEE-C CS
  ADH_zinc_N_2  32 gealleaslkvl.pggGrlvsiggpplsaallk 63 
                   g ++++a+ k+  ++ G++v+i g   + +l+ 
    EEA21693.1 166 GVTAYAALKKCEgQP-GDFVVIMGA--TGGLGH 195
                   555545555555455.999888863..344443 PP

  == domain 2  score: 19.1 bits;  conditional E-value: 6.9e-07
                   T-EEEEEES-HHHHH.HHHHHHEEEEEEEEE----....S-EEE-CHHHCTTT-EEEE--GGG...-.-HHHHHHHHHHHHHHH----EEEEEEGGG CS
  ADH_zinc_N_2  21 egvDvvldtvggealleaslkvlpggGrlvsiggpp...lsaallkpakkrkgrsvkyeflfsmkasaqadileelaalieeGklrpvvdrvfplee 114
                   ++  v+++t+ +ea+ +a+lkvl+  G+lv++g p    ++ a+++pa+   ++ ++++  +    + ++d   e + l +++ ++++   v p+++
    EEA21693.1 254 GAAAVIVCTASNEAY-AAALKVLRFAGTLVCVGVPEgkqVPIATADPAS-LISKEIRIVGSL--VGN-RQD-AIETLSLAAKEVVKTRFR-VEPMSN 343
                   445677777778888.999****888******96665666666666666.444444444444..345.788.899999*********995.****** PP

                   HHHHHHHHHSS--SSEEEE CS
  ADH_zinc_N_2 115 aaeAhrylesgrarGKiVl 133
                   +++ ++++ +   +G++Vl
    EEA21693.1 344 LQQVFEQMDNMELKGRVVL 362
                   ******************8 PP

>> Glu_dehyd_C  Glucose dehydrogenase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.2   1.1e-06    0.0032      33     204 ..     183     353 ..     168     363 .. 0.72

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 1.1e-06
  Glu_dehyd_C  33 salvlGa.GslGLLalalleaeerglervyvlgrrdrpdptidlveelGa......tYvdsretpvdeipeas...eemdlvvEaTGsakhafeaiea 120
                   ++++Ga G lG Lal +  a+ +g+e +  ++  d+     ++ +e Ga      t   s+e+ v+ i e +        v+ +T s ++  +a++ 
   EEA21693.1 183 FVVIMGAtGGLGHLALQM-GANGMGYE-MIGVDYGDKG----NFAKECGAntffdvTKYASNEDLVKAIKESTpdgLGAAAVIVCTASNEAYAAALKV 274
                  467888558999999555.45678888.3344544443....344444443111116666888888888655411134678999************** PP

  Glu_dehyd_C 121 lapnGvaaLlGvpedsevevdggelhrelvleNkalvGsvNanrrhfeaavdtLaalpeslldelvtkvvdldeleeAfeddde 204
                  l+ +G  + +Gvpe+++v + + +   +l+ +   +vGs   nr+    a++tL+ + ++++++   +v ++++l++ fe+ d+
   EEA21693.1 275 LRFAGTLVCVGVPEGKQVPIATADP-ASLISKEIRIVGSLVGNRQ---DAIETLSLAAKEVVKTR-FRVEPMSNLQQVFEQMDN 353
                  ****************999988775.567888899****998885...79*****9999998765.478899999999987653 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.2   4.2e-05      0.13       3      75 ..     184     249 ..     182     277 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 4.2e-05
                 EEEESTTSHHHHHHHHHHHH..TT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHH CS
   adh_short   3 vlvtGassGIGraiakelak..eGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkkl 75 
                 v++ Ga++G+G+  a ++ +  +G++++ vd+ ++   + ake++++        +Dvt++++ e+lv+++++ +
  EEA21693.1 184 VVIMGATGGLGHL-ALQMGAngMGYEMIGVDYGDK--GNFAKECGAN------TFFDVTKYASNEDLVKAIKEST 249
                 99*********84.455555025666666666654..57******96......679***************9876 PP

>> SAM_MT  Putative SAM-dependent methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.2      0.21   6.2e+02      62      97 ..     173     208 ..     162     211 .. 0.72
   2 ?    9.9   0.1   0.00015      0.44     164     203 ..     300     340 ..     295     361 .. 0.73

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.21
      SAM_MT  62 akavglkkgvlptvlDaTaGlGrDafvlaslGckvt 97 
                  k ++ + g    ++ aT GlG+ a  + + G+  +
  EEA21693.1 173 LKKCEGQPGDFVVIMGATGGLGHLALQMGANGMGYE 208
                 455555666678999*******99887777666555 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.00015
      SAM_MT 164 salvKKemrvfqqlvGadedadeLleaa.lalakkRvvVKr 203
                 ++l+ Ke+r++ +lvG+ +da e l++a +++ k+R  V  
  EEA21693.1 300 ASLISKEIRIVGSLVGNRQDAIETLSLAaKEVVKTRFRVEP 340
                 57899****************98887661556777776654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (366 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       424  (0.0236488); expected 358.6 (0.02)
Passed bias filter:                      355  (0.0198003); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 2500.61
//
Query:       EEA21694.1  [L=527]
Description: purine-cytosine permease FCY2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.6e-36  124.3  33.8    7.9e-36  123.8  33.8    1.2  1  Transp_cyt_pur  Permease for cytosine/purines, uracil, thiami


Domain annotation for each model (and alignments):
>> Transp_cyt_pur  Permease for cytosine/purines, uracil, thiamine, allantoin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.8  33.8   4.4e-40   7.9e-36       6     440 .]      77     506 ..      71     506 .. 0.78

  Alignments for each domain:
  == domain 1  score: 123.8 bits;  conditional E-value: 4.4e-40
  Transp_cyt_pur   6 eRtwktlnlfsiWlganlnintwvigalg.lalgLnwwqsvlviivgnligaifvallglaGakyGlpfpilsRasfGir.gsllplllrvviai 98 
                     ++   ++++f+i+++an n++t+++g lg +++gL+ww+s+l+i+++n++g+ + a+++  G+k+Gl+++i+ R+sfG + +++l +l+  vi  
      EEA21694.1  77 RTNQHPRDYFTIFFAANCNTATLATGFLGpVTFGLGWWDSFLAIVFFNVLGGLYPAVMATLGPKLGLRTMIIPRYSFGWWpAKILAILN--VINQ 169
                     445679************************************************************************66266777777..6666 PP

  Transp_cyt_pur  99 vwfgvqawiGsealllmlgki.fgkwleiggailgts.ltelvtffifwvvslvivllgvskirkffviaallvpvaafgfliwalvkaegGpvl 191
                     v++gv + i ++a+l+ +g+  ++ +      i++++ + +++++f++ v++++  + ++  + ++f+i+a       fg+  ++ v  + G++ 
      EEA21694.1 170 VGWGVVNCISGAAVLSDVGSHgIPMFA----SIIIVGiIAIVLGLFGYKVLHFYSRYSWMIML-VCFAITA------GFGARHFMNVPMGSGSLE 253
                     666777777777777777766033222....23344414566789999999999999998654.4444433......344555555555555443 PP

  Transp_cyt_pur 192 dkavklgkselflsavagvlagfatlilnapDFtryaktkkssvkiqlvavpllftlllligilvaaaakaa.yganawspldilakfdet.... 281
                        +++    +f ++++g++a++a++++   D+ +y+++ ++++ ++  a+++l++  +l+ +l+aa+++     ++  ++      +de+    
      EEA21694.1 254 A--SNIL---SFSTSIIGFQAAWAPIAA---DYGVYMREDTKATVTFSWAYAGLLSGQILLELLGAAIGTLYmNPDPRFQTA-----YDEHglgg 335
                     3..3333...488***************...************************************998774555555555.....88888888 PP

  Transp_cyt_pur 282 ...............agvllililvalaqlgvnisanllsagldlaallP..kkinikrgsliaavialvivpwkllssssklftaflsllavfl 359
                                    +g+++ +++ +++     i+ n++s gl ++ ++     +++ + s++ +++ l+i+++ l   ++ +  +fl + a+ l
      EEA21694.1 336 lfgsvyeginpgvrgFGYFIEVLIGLSTA--AVITTNIYSLGLSVQMITKklVIVPRPVWSFVGSIAFLAIALA-LRDHFEDVLENFLLVCAYWL 427
                     88999*******99888888776655544..446789***********99644555556666666666666665.8888988899********** PP

  Transp_cyt_pur 360 spvagviiadyfvvrrgylklaalytrrrgsaYwyrkgvNwravaayivGiaaglvgvagsvg....ikvvkgaeklfdlsylvG 440
                      p+  v+i + f+ rr y+   +   ++   +Y        +a +a+++G+a+++v ++ s         ++g   + d+s+++G
      EEA21694.1 428 VPFCMVLILEHFIWRRHYEYDLNAWNDHTRLPYG------IAAGVAWVCGTAIAVVSMSQSWWigpiAAAIPGSSYGTDISWILG 506
                     *******************999999999999999......78889************9998884444444555556677888877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (527 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       888  (0.0495287); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.47
# Mc/sec: 3404.56
//
Query:       EEA21695.1  [L=323]
Description: transposable element tc3 transposase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.9e-18   64.8   0.1    1.2e-17   64.0   0.1    1.4  1  DDE_3          DDE superfamily endonuclease
    4.5e-08   33.6   6.9    2.5e-05   24.8   0.5    2.5  2  HTH_32         Homeodomain-like domain
     0.0033   17.6   0.2      0.022   15.0   0.0    2.3  2  HTH_Tnp_Tc3_2  Transposase


Domain annotation for each model (and alignments):
>> DDE_3  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.0   0.1     2e-21   1.2e-17       2     135 ..     122     265 ..     121     272 .. 0.74

  Alignments for each domain:
  == domain 1  score: 64.0 bits;  conditional E-value: 2e-21
       DDE_3   2 vvfiDEsgfqlgt..vrrrawakkGkr.....er.leeygrrgrv.nligaldekgglafvtfeetlnaedfaeflerlletalqak...kivlilDna 88 
                 v++ DEs+++ g+      +w+ + ++      r +++ ++ +++ ++   ++ ++ l++ t +++ +  ++a++++++  ++l +    + ++  Dna
  EEA21695.1 122 VIWSDESTVERGKggQLIWTWNDPSEQlvehdVReIRTGKSIKKMfWAAFRYNMRTSLVPLTSDGSSRGGITATVIRQTYMNQLPELlenGDIFMQDNA 220
                 5666666666655333334444444444322122233344444430333445566677779*******************9999977999********* PP

       DDE_3  89 siHkseslrelveeeadrlellylPpySPelNpiEivwsklkrellk 135
                 ++H+++ +r+l++e   ++e++ +PpySP+lNpiE++w ++k+ +++
  EEA21695.1 221 PVHTAHIIRDLLRE--MQVEVMIWPPYSPDLNPIENLWAIMKTIIRQ 265
                 **************..***************************9987 PP

>> HTH_32  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.5   1.5   2.8e-05      0.17      19      71 ..       3      48 ..       1      50 [. 0.74
   2 !   24.8   0.5   4.2e-09   2.5e-05       1      71 [.      45     109 ..      45     110 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 2.8e-05
      HTH_32 19 drprrgrprklsdevrariiallreeprWsprqlaarlaeregvkvShstvyr 71
                +r+r  ++r l++  rari++l  +  rW+++++++        ++  st+++
  EEA21695.1  3 PRRRT-ARRELDPCMRARICELH-TSARWGYKRIHKVH-----PEIPISTIRN 48
                45444.4446*************.666*******9955.....4477777775 PP

  == domain 2  score: 24.8 bits;  conditional E-value: 4.2e-09
      HTH_32   1 TvsrwlkRyneeGlegLkdr..prrgrprklsdevrariiallreeprWsprqlaarlaeregvkvShstvyr 71 
                 T+++++k+ ++e    + +r  pr+g p+kls e+++ +i+l++e+p+  + +l++++ + +    S+ t++r
  EEA21695.1  45 TIRNTIKK-EQE---RVNQRslPRSGQPSKLSSEQKENLIQLTKENPHIKYYELQEYV-DMR---CSKTTIRR 109
                 67777777.555...4444444779******************999************.544...9******9 PP

>> HTH_Tnp_Tc3_2  Transposase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.1      0.34     2e+03      32      42 ..      43      53 ..      33      57 .. 0.79
   2 !   15.0   0.0   3.6e-06     0.022       2      37 ..      77     109 ..      76     121 .. 0.93

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.34
  HTH_Tnp_Tc3_2 32 reTirrrLrka 42
                    +Tir++++k+
     EEA21695.1 43 ISTIRNTIKKE 53
                   58999999987 PP

  == domain 2  score: 15.0 bits;  conditional E-value: 3.6e-06
  HTH_Tnp_Tc3_2   2 rrIvrlvrkdPritlreLanelkeeGksvsreTirr 37 
                     ++++l++++P+i + eL++ +      +s++Tirr
     EEA21695.1  77 ENLIQLTKENPHIKYYELQEYV---DMRCSKTTIRR 109
                    689*******************...**********8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (323 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       720  (0.0401584); expected 358.6 (0.02)
Passed bias filter:                      526  (0.0293379); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2192.83
//
Query:       EEA21696.1  [L=1279]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      2e-94  316.9   0.0    3.8e-94  316.1   0.0    1.4  1  MMS1_N       Mono-functional DNA-alkylating methyl methanesul
    4.7e-07   29.4   0.0    1.4e-06   27.8   0.0    1.8  1  CPSF_A       CPSF A subunit region
  ------ inclusion threshold ------
       0.11   12.5   0.1        5.6    7.0   0.0    3.0  3  Tricorn_PDZ  Tricorn protease PDZ domain
        5.3    7.7   9.4         30    5.3   0.0    5.5  6  PQQ_3        PQQ-like domain


Domain annotation for each model (and alignments):
>> MMS1_N  Mono-functional DNA-alkylating methyl methanesulfonate N-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  316.1   0.0   8.4e-98   3.8e-94       1     472 [.     112     615 ..     112     641 .. 0.86

  Alignments for each domain:
  == domain 1  score: 316.1 bits;  conditional E-value: 8.4e-98
      MMS1_N   1 DlLvvgsdsgelvfl..synpeknqfetvhshetlgksgsrrsqpGqylavDPkgraiavsayekvflvyslkk.....keilnrealllssplea... 89 
                 ++L++++ds+el+fl  +  + +n++ +vh+++ l++++s  +++G++lavDP++ra+av+a  ++f+v++lk      ++i+     l   p+ +   
  EEA21696.1 112 HILALTLDSRELLFLycHSGSPDNDVGFVHFRRALPSDVSISERFGRHLAVDPRSRAVAVAAPADFFGVFMLKAsgelhSQIKG--GTL--APIAEerf 206
                 58*************9977777****************************************************8665544444..444..69998899 PP

      MMS1_N  90 rksegvilsmvFldpgykeednpiialleqdrrgkteltlyewdlglnlvrkisktsepkk.......nldsganlLiplpkpgg.vlVcgetiitykd 180
                 ++ eg+i++m+Fl+ +++e +n i++ll+++r   t ++ y wd  ++++++++k+  ++k             nlLipl+k++  +l++++ ii+ ++
  EEA21696.1 207 YRLEGHIMFMDFLYSPENE-KNNIVLLLIVSRGPLTYAMHYIWDSEKGVRQAQPKPI-TSKlpdfcrlP-----NLLIPLTKSSNyLLITPSFIIINRN 298
                 *****************86.559999999*******************999999863.34478555442.....7*******5558************* PP

      MMS1_N 181 ildqedirkk...............swarPrrekatnfvawekldsfffllatedGdLylleiekdedsgkvvtsislkyfdtvsvasalvilksgf.. 262
                  l+ +  r+k               +warP+r+ +++      +d  +++l++edG+L+++ei++ ++  + ++   +++ ++++v++a+++++ ++  
  EEA21696.1 299 PLSPNSKRVKqrcsdliskspsiwaKWARPYRHPKYD----ILHD--DVFLCREDGRLTYVEIDN-KG--QIESINVIGQ-LDCEVDAAFDTIDFNHps 387
                 *99777665579*************************....99**..****************66.44..5688889999.9***************** PP

      MMS1_N 263 .....LfvasefGdgqlyqieargeddknleliqtldNlaPilDfkvv.....kes......dlasegqdqiytcs.GagkrgsLrelRsGieveela. 343
                      L++a+++G+g+l++++ar   + n+e++q++ N+aP++D+++v     k         ++ ++   +y+ s +++++g++ e+R+G+e+++++ 
  EEA21696.1 388 hggdlLIAAGSTGHGGLFIQTAR---Q-NPECVQRFVNWAPVFDTVIVpplqkK-AghefdmTKDLSDDLHLYVSSaSSNNSGAVYEFRHGYEAQIGMi 481
                 **********************9...4.9*********************9742.25778763355677899**************************9 PP

      MMS1_N 344 vseepgspitgvWtlklssedeyd.dylvlSfvneTlvlsid....gdgeveevt..e.ds.glllsvpTLaagnlgdgslvQVtpngirliradk... 430
                 +  e+++ +++vW+++     ++d +y+++S++ ++ +++++    g  e +e++  + ++  l+lsv++Laag +++g+l QVt+n +r +  ++   
  EEA21696.1 482 IPLEDFTTARAVWVIPD---FSQDgTYFLISDPISSALMHLSrnesG--EGDEIYavDgSDlSLDLSVNSLAAGYTSTGVLFQVTSNAVRAVLLNNpei 575
                 99999***********3...33566*****************88653..4466666655666***************************9988888878 PP

      MMS1_N 431 .rvsewkppngksiiaaaangeqllvalsgrelvyfeldliee 472
                  +vs+++ ++  ++ +a++++e+ lva++ r+++++++ ++ +
  EEA21696.1 576 nCVSDFSIDQ--TVLVATLSEELELVAVALRSEQGISI-QVGR 615
                 8888888885..9********99999999999999888.3333 PP

>> CPSF_A  CPSF A subunit region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0   3.2e-10   1.4e-06      38     286 ..     931    1173 ..     917    1213 .. 0.74

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 3.2e-10
                  TTT---B--EEEEEEE---SSS--E.EEEEEEEEEE-...SS--EEEEEEEEEEEES----EEEETTE.EEEE-SSEEEEEE..E-TTS.-EEEEEE CS
      CPSF_A   38 ettkekkellvVGtafnlgedpaarsGrilvfeiiev...petnrkLklvhkeevkgavtalaefqGr.llvgvgqkvrvyd..lgedk.tLlrkaf 127 
                  et ++k +llvVGta   +e+     Gr++ +  + +   pe + +  l + +  +g+v+a+a + +  ++v+ g+ ++     l + + +  + a+
  EEA21696.1  931 ETGGQKYHLLVVGTARKTQEQS----GRVIFLNAKRNaanPE-QIDCSLKYIHTFDGPVRAIAAYGDStIMVASGNDIIPIAprLPNGGeQWAAAAR 1022
                  34467899**********9977....9**********99844.555555566689**********7766*******998554114444467999999 PP

                  EE-SS-EEEEEEETTEEEEEESSS-EEEEEE-SSS--EEEEEEESS---EEEEEEE--SSS.EEEEEETTSEEEEEE--TTSGGGTTTT.EEEEEEE CS
      CPSF_A  128 ldtqlyvvslkvlgnriivgDlmkSvtfveydeenyklilfardtqkrwvtaaeflvdged.tvlvaDkfgnlfvlrydpeasessdgdprleerae 223 
                  ++ +   vs+ v  ++++++ +++S++++++   n+kl l a+d  +++  + + +  ge+  +lv+ + g +  +  +    +++d+      +ae
  EEA21696.1 1023 FKLTSPGVSIIVRDTLLYISTARESLVILQV--VNKKLELYAQDGVRHESLSHQYI-GGENdLTLVSHRGGTISAFSAA--GVTDMDKI-ISPAIAE 1113
                  99999999****9******************..6788*********9999999999.55555***********999999..57777766.6666666 PP

                  EE-SS----E...EEEE..SSS--S-EEEEEE-TTS-EEEEEE.--HHHHHHHHHHHHHHHHHS CS
      CPSF_A  224 fhlgeivtslrkgslvp.geaesssspqllyatldGsigllvPliseeeyrrlqaLqqqLrkel 286 
                   +l   + +l   +     + +ssssp +  +t dG+i+ +   ++e++ r+l+ Lq+  +k+ 
  EEA21696.1 1114 AQLPVSIIRL---NACDdPSLQSSSSPVVYGTTTDGAIYRIST-LTEKQWRLLRFLQNLCSKDS 1173
                  6666555555...333343334445899***********8888.************97655443 PP

>> Tricorn_PDZ  Tricorn protease PDZ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.0    0.0013       5.6      42      79 ..     526     563 ..     519     569 .. 0.89
   2 ?   -2.8   0.0       1.5   6.5e+03      35      47 ..     606     618 ..     603     620 .. 0.88
   3 ?    1.4   0.0     0.071   3.2e+02      22      49 ..    1014    1041 ..    1011    1048 .. 0.87

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0013
                  TT-EEEEETTEE-BTTB-HHHHHHTTTTSEEEEEEE-S CS
  Tricorn_PDZ  42 eGdlilavdgepvskekgiaelLvgkagkeveLtvkrk 79 
                  eGd i+avdg ++s + ++++l +g + + v  +v+++
   EEA21696.1 526 EGDEIYAVDGSDLSLDLSVNSLAAGYTSTGVLFQVTSN 563
                  8**************************99999999875 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1.5
                  GGS---.TT-EEE CS
  Tricorn_PDZ  35 epGvnvreGdlil 47 
                  e+G+ +++G +il
   EEA21696.1 606 EQGISIQVGRAIL 618
                  78********997 PP

  == domain 3  score: 1.4 bits;  conditional E-value: 0.071
                   S-TTSSS-B-GGGGGS---.TT-EEEEE CS
  Tricorn_PDZ   22 GdswdeearSPLaepGvnvreGdlilav 49  
                   G++w  +ar  L+ pGv + + d++l +
   EEA21696.1 1014 GEQWAAAARFKLTSPGVSIIVRDTLLYI 1041
                   9****************99887777665 PP

>> PQQ_3  PQQ-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.1       3.3   1.5e+04      19      33 ..     552     565 ..     544     568 .. 0.73
   2 ?    5.3   0.0    0.0068        30      20      36 ..     648     664 ..     635     667 .. 0.81
   3 ?   -1.2   0.1      0.71   3.2e+03       9      30 ..     980    1001 ..     975    1003 .. 0.74
   4 ?    1.0   0.0      0.14   6.4e+02       2      33 ..    1014    1048 ..    1013    1052 .. 0.74
   5 ?   -3.2   0.0       3.2   1.4e+04      23      38 ..    1082    1097 ..    1075    1098 .. 0.63
   6 ?    2.0   0.0      0.07   3.1e+02      23      36 ..    1138    1151 ..    1127    1155 .. 0.86

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 3.3
       PQQ_3  19 vdgglvyvgtgdGtl 33 
                 ++ g+++ +t+ + +
  EEA21696.1 552 TSTGVLFQVTS-NAV 565
                 68999999998.555 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0068
       PQQ_3  20 dgglvyvgtgdGtlyAl 36 
                 dg +++vgt+dG l  +
  EEA21696.1 648 DGAYLFVGTSDGYLAYY 664
                 6779********99866 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 0.71
       PQQ_3    9 lpgpvnsspavdgglvyvgtgd 30  
                  ++gpv + +a+++ ++ v++g+
  EEA21696.1  980 FDGPVRAIAAYGDSTIMVASGN 1001
                  5667744448889999999986 PP

  == domain 4  score: 1.0 bits;  conditional E-value: 0.14
       PQQ_3    2 evlWsv....qlpgpvnsspavdgglvyvgtgdGtl 33  
                   ++W+     +l +p++ s  v + l+y++t   +l
  EEA21696.1 1014 GEQWAAaarfKLTSPGV-SIIVRDTLLYISTARESL 1048
                  56677766667788874.6899********986665 PP

  == domain 5  score: -3.2 bits;  conditional E-value: 3.2
       PQQ_3   23 lvyvgtgdGtlyAlDa 38  
                  l  v+   Gt+ A+ a
  EEA21696.1 1082 LTLVSHRGGTISAFSA 1097
                  3344455999999987 PP

  == domain 6  score: 2.0 bits;  conditional E-value: 0.07
       PQQ_3   23 lvyvgtgdGtlyAl 36  
                  +vy +t+dG +y +
  EEA21696.1 1138 VVYGTTTDGAIYRI 1151
                  799********976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1279 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       414  (0.0230911); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.92u 0.34s 00:00:01.26 Elapsed: 00:00:00.59
# Mc/sec: 6547.74
//
Query:       EEA21697.1  [L=861]
Description: DNA replication licensing factor Mcm3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.5e-94  314.6   0.0    4.6e-94  313.7   0.0    1.4  1  MCM              MCM P-loop domain
    1.5e-30  105.6   0.0    2.7e-30  104.8   0.0    1.4  1  MCM_OB           MCM OB domain
    7.6e-25   87.2   0.8    1.5e-24   86.2   0.8    1.5  1  MCM_lid          MCM AAA-lid domain
    9.4e-12   45.4   0.0    3.4e-11   43.7   0.0    1.9  1  MCM_N            MCM N-terminal domain
    1.4e-06   27.9   0.0    1.6e-05   24.4   0.0    2.3  2  Mg_chelatase     Magnesium chelatase, subunit ChlI
     0.0031   17.4   0.0     0.0074   16.2   0.0    1.7  1  AAA_3            ATPase family associated with various cellul
  ------ inclusion threshold ------
      0.027   14.5   0.0       0.25   11.4   0.0    2.6  2  AAA_5            AAA domain (dynein-related subfamily)
        0.1   12.3   0.0       0.27   10.9   0.0    1.6  1  Sigma54_activat  Sigma-54 interaction domain
        2.7    6.5  11.6          4    5.9  11.6    1.1  1  TFIIF_alpha      Transcription initiation factor IIF, alpha s


Domain annotation for each model (and alignments):
>> MCM  MCM P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  313.7   0.0   2.3e-97   4.6e-94       3     224 .]     291     514 ..     289     514 .. 0.96

  Alignments for each domain:
  == domain 1  score: 313.7 bits;  conditional E-value: 2.3e-97
                 HHHHHHHT..SSTHHHHHHHHSSTTSSS-HHHHHHHHHHHH---EBBBSSSSBBCSS-EEEEEESSTSTHHHHHHHHHHHSSSEEEEESSSSSSSHSSS CS
         MCM   3 eeikelak..ekdiieklvksiapsiyghedvkkaillqlfggvkkkledktklrgdinvllvgdpgtaKsqlLkyveklapravytsgkgssaagLta 99 
                 ++i++ ak  +++i+++l++s+apsiyghe +kka+ll+l+gg++k+l+++t+lrgdin+l+vgdp+taKsq+L++v ++ap a+ t+g+gss++gLta
  EEA21697.1 291 RNINKWAKskKTKIFNMLAQSLAPSIYGHEYIKKAVLLMLLGGIEKNLDNGTHLRGDINILMVGDPSTAKSQMLRFVLNTAPLAIATTGRGSSGVGLTA 389
                 56776654115689************************************************************************************* PP

                 EEEEESSSSSEEEEETHHHHTTTSEEEEESGGGSTCHHHHHHHHHHHHSEEEEESSSCEEEEE--EEEEEEE--SSSSCCTTS-HHHHSSSSHHHHHHS CS
         MCM 100 avvrdeetgefvleaGalvladkGvcciDefdkmkeedrsalhEamEqqtisiaKaGivatLnartsvlaAanpkagrydkkksvaeninlsaalLsrF 198
                 av+ d+etge  leaGa+vl d+Gv+ciDefdkm++ dr+a+hE+mEqqt++iaKaGi+++Lnar+sv+aAanp++g+yd++k  ++ni l+++lLsrF
  EEA21697.1 390 AVTTDKETGERRLEAGAMVLGDRGVVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTSLNARCSVIAAANPIYGQYDPHKDPHKNIALPDSLLSRF 488
                 *************************************************************************************************** PP

                 SEEEEE-SSTTHHHHHHHHHHHHHHH CS
         MCM 199 DlifvllDkvdeekDeelaehivslh 224
                 Dl+f++ D+++++ D+ ++eh+++ h
  EEA21697.1 489 DLLFIVTDDPEDKGDRLVSEHVLRRH 514
                 **********************9876 PP

>> MCM_OB  MCM OB domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.8   0.0   1.4e-33   2.7e-30       3     124 ..     117     247 ..     114     249 .. 0.88

  Alignments for each domain:
  == domain 1  score: 104.8 bits;  conditional E-value: 1.4e-33
                 GG--GGGTTSEEEEEEEEEEE---EEEEEEEEEEETTT-.-EEES---..............-SB-..TTT-HHH-EEE-GGGSEEEEEEEEEEE---- CS
      MCM_OB   3 RdlrsehigklvkveGivtrasevkpklkkavfeckkcgktvevelee..............PrkCeekeCeskdpfkletekskfvdfqklklQEspe 87 
                 R+l s+h++++v++eGivt++s v+pk+ ++v+  +k +k    ++++              P++      ++k+p++ e   ++++d+q++++QE+pe
  EEA21697.1 117 RTLGSSHLNRMVSLEGIVTKCSLVRPKIIQSVHFSEKKNKFFARKYRDqtmtasgatslnvyPQED-----DEKNPLTTEFGYCTYMDHQTISIQEMPE 210
                 99********************************99999876666666566667777777777632.....34789999999***************** PP

                 ---------EEEEEEEGGGTT---TT-EEEEEEEEEE CS
      MCM_OB  88 evpaGelPrslevileddlvdkvkPGdrvevtGiyra 124
                 ++paG+lPr ++vil+ddlvd++kPGdr++++Gi+r+
  EEA21697.1 211 RAPAGQLPRGVDVILDDDLVDRAKPGDRIQLVGIFRS 247
                 **********************************996 PP

>> MCM_lid  MCM AAA-lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.2   0.8   7.5e-28   1.5e-24       2      84 ..     579     662 ..     578     665 .. 0.94

  Alignments for each domain:
  == domain 1  score: 86.2 bits;  conditional E-value: 7.5e-28
                 HHHHHHHHHHHTT--BETCHHHHHHHHHHHHHHHHH.TSSTSSSST--HHHHHHHHHHHHHHHHHHTSSSE-HHHHHHHHHHHH CS
     MCM_lid   2 llrkYiayarekikPklseeakeklseaYvelRkee.edskrksipitvRqLesliRLseAlAklrlsevvteedveeairllk 84 
                 +++kYi+ya+++ikP+l++ a+++++ +Y  lR+++ ++++rk+ p+t+R+Le+liRLs+A+Ak rls+ v+e+d++ea  +l+
  EEA21697.1 579 FIKKYIQYAKTRIKPVLTKGAADHIVATYSALRNDDlTGNQRKTSPMTARTLETLIRLSTAHAKARLSNRVEEKDAKEAEAILR 662
                 68*********************************976669**************************************98876 PP

>> MCM_N  MCM N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.7   0.0   1.7e-14   3.4e-11       7      98 ..      21     101 ..      16     118 .. 0.85

  Alignments for each domain:
  == domain 1  score: 43.7 bits;  conditional E-value: 1.7e-14
       MCM_N   7 FLeefkddsededgekkYrdqlqemaerekttLevdlddLaafdeeLaeailenpkeylplleealkevvkklepsykddakefpaeltrrf 98 
                 FL+       ++   + Yr+ +  m++r+ ++L+v++d +++++ +La+ +l  p ey +++++alk+v+k+l ++ +++       ++  +
  EEA21697.1  21 FLD------PTDTRARSYRADIVLMLNRGLRRLTVSIDEIRSHNGDLAQGLLMSPFEYTEAFNKALKNVIKTLPNRPARE-----TAEDVIY 101
                 555......3466789******************************************************9988876665.....4444555 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.0      0.19   3.7e+02      21      40 ..     346     365 ..     342     375 .. 0.83
   2 !   24.4   0.0     8e-09   1.6e-05      93     160 ..     398     465 ..     392     491 .. 0.90

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.19
  Mg_chelatase  21 GgHnlllvGppGsGKtmlak 40 
                   G  n+l+vG p + K+ + +
    EEA21697.1 346 GDINILMVGDPSTAKSQMLR 365
                   7889***********97755 PP

  == domain 2  score: 24.4 bits;  conditional E-value: 8e-09
  Mg_chelatase  93 ggskpkpGeislahnGvLfLDElpefkrkvlevLRePledgevtisrakakvefparfqlvaamNpcp 160
                   g ++ + G++ l  +Gv+ +DE+ +++     ++ e +e+++vti++a  +++  ar+ ++aa+Np  
    EEA21697.1 398 GERRLEAGAMVLGDRGVVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTSLNARCSVIAAANPIY 465
                   5668899*********************9999**********************************75 PP

>> AAA_3  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   3.7e-06    0.0074      44     114 ..     390     465 ..     349     490 .. 0.77

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 3.7e-06
       AAA_3  44 tevfeekekefefkkGpvf...anllladeinrappktqsalleameerqvtvege..thklpepflvlatqnPie 114
                 +   ++++ e ++++G+++     ++  de ++ +   + a+ e+me+++vt++++   ++l+    v+a+ nPi 
  EEA21697.1 390 AVTTDKETGERRLEAGAMVlgdRGVVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAgiHTSLNARCSVIAAANPIY 465
                 455667778888888887633336999*************************9875226789************94 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0      0.62   1.2e+03      30     103 ..       4      84 ..       3     117 .. 0.66
   2 ?   11.4   0.0   0.00012      0.25       1     125 [.     349     466 ..     349     488 .. 0.78

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.62
                 EE--TT--HHHHH--B--..............--------...G-SEEEEESGGG--.HHHHHHHHHHHHSSEEE..-SSSEE CS
       AAA_5  30 vqltrdtteedlkgrreik.....ngttslvdsplvraar...egeilvlDEverae.sevlnsLlslleerrllleeggelv 103
                 vql++dt e+ ++  +e+        +  + d +l+   +   +  ++ +DE+   + + +++ L+s++e  +     +++++
  EEA21697.1   4 VQLPEDTAEDRVLAATEFLdptdtRARSYRADIVLML--NrglRRLTVSIDEIRSHNgDLAQGLLMSPFEYTEAFNKALKNVI 84 
                 6788888888888888877665534444455555552..12457888889999988855566667777776665555555555 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00012
                 EEEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--...........--------G-SEEEEESGGG--HHHHHHHHHHHHSSEEE.. CS
       AAA_5   1 dvlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreik..ngttslvdsplvraaregeilvlDEveraesevlnsLlslleerrllle 97 
                 ++l+vG+p t+Ks++ + ++   ++++ +    r+ +   l+  + ++   g+++l+ +++v       ++++DE++++++    + + ++e++++ ++
  EEA21697.1 349 NILMVGDPSTAKSQMLRFVLN--TAPLAIATTGRGSSGVGLTAAVTTDkeTGERRLEAGAMV--LGDRGVVCIDEFDKMSDVDRVAIHEVMEQQTVTIA 443
                 579999999999998776554..555556666666666666666666555555556777777..7788899***********9**************** PP

                 -SSSEEE---......-EEEEEESS--. CS
       AAA_5  98 eggelvkaknddllerfrviatanpldr 125
                 + g  ++ ++       +via+anp ++
  EEA21697.1 444 KAGIHTSLNAR-----CSVIAAANPIYG 466
                 99999999886.....9********983 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00013      0.27      79     142 ..     397     462 ..     394     468 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00013
                      TTTSS-BEHHHHHTTTSEEEEETGGGS-HHHHHHHHHHHHHSEE..ESBTSSSEEE--EEEEEEES CS
  Sigma54_activat  79 tGAekekkGlfekadgGtlfLDeigelplelQekLlrvlqegev..ervGsskeikvdvriiaatn 142
                      tG ++ ++G++   d G++ +De  +++    + + +v+++++v   + G +++ ++ + +iaa+n
       EEA21697.1 397 TGERRLEAGAMVLGDRGVVCIDEFDKMSDVDRVAIHEVMEQQTVtiAKAGIHTSLNARCSVIAAAN 462
                      67777889*******************************9997522699***************97 PP

>> TFIIF_alpha  Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9  11.6     0.002         4     322     428 ..     650     758 ..     638     786 .. 0.56

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.002
                  XXXXXXXXXXXXXXXXXXXXXXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXX CS
  TFIIF_alpha 322 keeekkeeegklskkkkkakklkkkkkekdkkdSddeedsddsDideedsvslvkakKkkek...kkeekvdsnessagnsrparpspeqkdskskrk 416
                  +e++ ke e  l     k+  + ++kk+ +    d++edsddsD+d+e+ +     ++   +   ++ e vds++ ++ +  ++     q +s+++r 
   EEA21697.1 650 EEKDAKEAEAILRFALFKEVVEDSRKKRRKVTTFDSDEDSDDSDDDTEEPSEPASSRRSGRRaglRSMETVDSAPLESEAPESSYRDQPQ-SSRTTRG 746
                  566666666666665555555555555555566666777777777777655544444444440115556666665444443333333332.3366777 PP

                  XX..XXXXXX.. CS
  TFIIF_alpha 417 aaseeskspvsv 428
                  ++++es+++v++
   EEA21697.1 747 QTQTESQMSVAS 758
                  788899988743 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (861 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       756  (0.0421663); expected 358.6 (0.02)
Passed bias filter:                      429  (0.0239277); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.72u 0.32s 00:00:01.04 Elapsed: 00:00:00.50
# Mc/sec: 5193.61
//
Query:       EEA21698.1  [L=1254]
Description: translation regulator (Cya5), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-22   79.0   0.2    1.4e-12   47.6   0.0    7.8  9  PPR_2     PPR repeat family
    1.7e-16   59.2   7.8    1.8e-05   24.6   0.0    9.7 11  PPR       PPR repeat
    2.9e-15   56.1   0.0    2.3e-06   27.6   0.0    5.0  5  PPR_3     Pentatricopeptide repeat domain
    2.7e-07   30.2   0.0      0.063   12.6   0.0    4.0  4  PPR_long  Pentacotripeptide-repeat region of PRORP
    3.9e-07   29.6   0.3       0.78    9.5   0.0    4.7  5  PPR_1     PPR repeat
     0.0046   17.7   3.7        4.7    8.3   0.0    5.6  5  TPR_14    Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.028   14.3   0.2       0.15   11.9   0.2    2.4  1  TPR_10    Tetratricopeptide repeat
       0.12   12.0   1.0       0.23   11.0   0.2    1.8  2  SHQ1      SHQ1 protein


Domain annotation for each model (and alignments):
>> PPR_2  PPR repeat family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   0.0     0.011        24       1      31 [.     429     459 ..     429     464 .. 0.93
   2 !   47.6   0.0     6e-16   1.4e-12       4      49 ..     515     560 ..     512     561 .. 0.93
   3 ?    3.4   0.0     0.039        87       6      25 ..     587     606 ..     584     609 .. 0.85
   4 !    7.3   0.0    0.0024       5.3       6      45 ..     623     662 ..     620     667 .. 0.89
   5 !    7.7   0.0    0.0018       4.1       2      48 ..     654     701 ..     654     703 .. 0.93
   6 ?    0.1   0.0      0.41   9.2e+02       5      32 ..     693     720 ..     689     721 .. 0.87
   7 ?   -2.4   0.0       2.6   5.7e+03       8      26 ..     847     865 ..     846     866 .. 0.85
   8 ?    1.6   0.0      0.15   3.3e+02       6      38 ..     961     993 ..     960    1002 .. 0.90
   9 ?   -1.6   0.0       1.5   3.3e+03       5      11 ..    1082    1088 ..    1081    1098 .. 0.64

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.011
       PPR_2   1 pdvvtyNtlIsglckkgkveeAfklfneMkk 31 
                 p++ +yN  + ++ + g+v +  + fn+M++
  EEA21698.1 429 PSIGAYNYALLAFSRSGDVPKTQETFNKMVE 459
                 67889************************86 PP

  == domain 2  score: 47.6 bits;  conditional E-value: 6e-16
       PPR_2   4 vtyNtlIsglckkgkveeAfklfneMkkrglePnsyTysilikglc 49 
                 +++N+lIs+++++++v+ Af+++  M+++g++P+ yTy +l+  ++
  EEA21698.1 515 HCWNALISAHANARNVRGAFRVWRRMQRKGVPPDWYTYGTLMGMCA 560
                 78****************************************6655 PP

  == domain 3  score: 3.4 bits;  conditional E-value: 0.039
       PPR_2   6 yNtlIsglckkgkveeAfkl 25 
                 + t+  ++c++ +++eA ++
  EEA21698.1 587 MDTVVEAYCRNQRFQEAEDM 606
                 668999***********886 PP

  == domain 4  score: 7.3 bits;  conditional E-value: 0.0024
       PPR_2   6 yNtlIsglckkgkveeAfklfneMkkrglePnsyTysili 45 
                 +N+l+  ++ + ++++  ++   Mk+ g+e ++ Ty  ++
  EEA21698.1 623 WNVLLYSHALRADLDSVSRIQTRMKEAGIEFDEMTYAAIM 662
                 8999999999999999999999**************8776 PP

  == domain 5  score: 7.7 bits;  conditional E-value: 0.0018
       PPR_2   2 dvvtyNtlIsglckkgkveeAfklfneMkk.rglePnsyTysilikgl 48 
                 d +ty +++ +++  g++++A +l+   ++ r ++ +++ y+ ++ g+
  EEA21698.1 654 DEMTYAAIMLCFVVIGQPNSARRLLRGLQRgRRIQATEFHYTLVLYGY 701
                 568***************************99**********999887 PP

  == domain 6  score: 0.1 bits;  conditional E-value: 0.41
       PPR_2   5 tyNtlIsglckkgkveeAfklfneMkkr 32 
                  y+ ++ g++++g+ ++ + + +eM++r
  EEA21698.1 693 HYTLVLYGYVQQGNRDMIYLINKEMEQR 720
                 6999**********99999999999875 PP

  == domain 7  score: -2.4 bits;  conditional E-value: 2.6
       PPR_2   8 tlIsglckkgkveeAfklf 26 
                 +l+  + ++g++e   k +
  EEA21698.1 847 VLMEVYSQDGNFEAVQKCW 865
                 5899********9988776 PP

  == domain 8  score: 1.6 bits;  conditional E-value: 0.15
       PPR_2   6 yNtlIsglckkgkveeAfklfneMkkrglePns 38 
                 + ++Is+  k+g++++  ++ ++ +krg++++s
  EEA21698.1 961 FSIYISMVGKAGQSSSLSEIVDDFQKRGFSMSS 993
                 568999999*******************98876 PP

  == domain 9  score: -1.6 bits;  conditional E-value: 1.5
       PPR_2    5 tyNtlIs 11  
                  tyN++I 
  EEA21698.1 1082 TYNVMIY 1088
                  6777775 PP

>> PPR  PPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.3   0.0    0.0056        13       3      28 ..     434     459 ..     432     461 .. 0.92
   2 !   24.6   0.0   8.1e-09   1.8e-05       2      31 .]     516     545 ..     515     545 .. 0.97
   3 !    7.4   0.2    0.0026       5.9       1      22 [.     550     571 ..     550     578 .. 0.84
   4 !    6.4   0.0    0.0054        12       5      22 ..     589     606 ..     587     611 .. 0.90
   5 ?    1.5   0.0       0.2   4.4e+02       2      31 .]     622     651 ..     621     651 .. 0.94
   6 ?   -0.5   0.0      0.85   1.9e+03       2      26 ..     657     681 ..     656     684 .. 0.88
   7 ?    1.4   0.0      0.21   4.7e+02       2      18 ..     693     709 ..     692     720 .. 0.77
   8 ?   -2.9   0.0       5.1   1.1e+04       7      18 ..     804     815 ..     802     822 .. 0.79
   9 ?    3.4   0.0     0.048   1.1e+02       4      24 ..     846     866 ..     845     871 .. 0.87
  10 ?   -1.9   0.0       2.3   5.3e+03       3      31 .]     961     989 ..     960     989 .. 0.84
  11 ?   -0.9   0.0       1.2   2.7e+03       2       8 ..    1082    1088 ..    1081    1098 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0056
         PPR   3 ynslIsgycknGkleeAlelfkeMke 28 
                 yn  + +++++G++ +  e f++M+e
  EEA21698.1 434 YNYALLAFSRSGDVPKTQETFNKMVE 459
                 888899******************98 PP

  == domain 2  score: 24.6 bits;  conditional E-value: 8.1e-09
         PPR   2 tynslIsgycknGkleeAlelfkeMkekGi 31 
                 ++n+lIs+++ +++++ A++++++M++kG+
  EEA21698.1 516 CWNALISAHANARNVRGAFRVWRRMQRKGV 545
                 7***************************97 PP

  == domain 3  score: 7.4 bits;  conditional E-value: 0.0026
         PPR   1 vtynslIsgycknGkleeAlel 22 
                 +ty +l+  +++ G++e  + l
  EEA21698.1 550 YTYGTLMGMCARLGDVENTIAL 571
                 69**************976665 PP

  == domain 4  score: 6.4 bits;  conditional E-value: 0.0054
         PPR   5 slIsgycknGkleeAlel 22 
                 +++ +yc+n +++eA+++
  EEA21698.1 589 TVVEAYCRNQRFQEAEDM 606
                 6889***********997 PP

  == domain 5  score: 1.5 bits;  conditional E-value: 0.2
         PPR   2 tynslIsgycknGkleeAlelfkeMkekGi 31 
                 ++n+l+ +++   +l+ + ++  +Mke Gi
  EEA21698.1 622 MWNVLLYSHALRADLDSVSRIQTRMKEAGI 651
                 8*************************9997 PP

  == domain 6  score: -0.5 bits;  conditional E-value: 0.85
         PPR   2 tynslIsgycknGkleeAlelfkeM 26 
                 ty +++ +++  G++  A +l++ +
  EEA21698.1 657 TYAAIMLCFVVIGQPNSARRLLRGL 681
                 8999999*************99865 PP

  == domain 7  score: 1.4 bits;  conditional E-value: 0.21
         PPR   2 tynslIsgycknGklee 18 
                  y+ ++ gy++ G+ ++
  EEA21698.1 693 HYTLVLYGYVQQGNRDM 709
                 7************8665 PP

  == domain 8  score: -2.9 bits;  conditional E-value: 5.1
         PPR   7 IsgycknGklee 18 
                 +++y+ +G+++ 
  EEA21698.1 804 LQAYSAEGMYRR 815
                 789999999875 PP

  == domain 9  score: 3.4 bits;  conditional E-value: 0.048
         PPR   4 nslIsgycknGkleeAlelfk 24 
                 ++l+ +y++ G++e + ++++
  EEA21698.1 846 SVLMEVYSQDGNFEAVQKCWD 866
                 689***********9999887 PP

  == domain 10  score: -1.9 bits;  conditional E-value: 2.3
         PPR   3 ynslIsgycknGkleeAlelfkeMkekGi 31 
                 +++ Is  +k+G+ +   e+ ++ +++G+
  EEA21698.1 961 FSIYISMVGKAGQSSSLSEIVDDFQKRGF 989
                 67779999999999999999999999986 PP

  == domain 11  score: -0.9 bits;  conditional E-value: 1.2
         PPR    2 tynslIs 8   
                  tyn++I 
  EEA21698.1 1082 TYNVMIY 1088
                  9*****6 PP

>> PPR_3  Pentatricopeptide repeat domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       2.8   6.3e+03       1      15 [.     239     253 ..     239     256 .. 0.88
   2 ?   -0.6   0.0      0.64   1.4e+03      12      41 ..     428     457 ..     418     460 .. 0.85
   3 !   27.6   0.0     1e-09   2.3e-06      18      60 ..     517     559 ..     509     561 .. 0.94
   4 !   13.7   0.0   2.1e-05     0.048      18      60 ..     623     665 ..     620     667 .. 0.85
   5 !    7.5   0.0    0.0019       4.2      14      44 ..     690     720 ..     676     726 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 2.8
       PPR_3   1 silremerkgikldv 15 
                 ++ +++++k+i +dv
  EEA21698.1 239 RLCDDAVAKDIDIDV 253
                 6889********998 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.64
       PPR_3  12 kldvvtYthLLtayanagnkklalevlerm 41 
                 ++++  Y+  L a+ + g+     e++++m
  EEA21698.1 428 QPSIGAYNYALLAFSRSGDVPKTQETFNKM 457
                 788889999999999999999999999998 PP

  == domain 3  score: 27.6 bits;  conditional E-value: 1e-09
       PPR_3  18 YthLLtayanagnkklalevlermkkkgikPtvvtyNailgvi 60 
                 +++L++a ana+n + a++v  rm+ kg+ P   ty  ++g++
  EEA21698.1 517 WNALISAHANARNVRGAFRVWRRMQRKGVPPDWYTYGTLMGMC 559
                 79****************************************9 PP

  == domain 4  score: 13.7 bits;  conditional E-value: 2.1e-05
       PPR_3  18 YthLLtayanagnkklalevlermkkkgikPtvvtyNailgvi 60 
                 ++ LL   a+  +++ +++++ rmk+ gi+   +ty ai+  +
  EEA21698.1 623 WNVLLYSHALRADLDSVSRIQTRMKEAGIEFDEMTYAAIMLCF 665
                 566777777777***************************9665 PP

  == domain 5  score: 7.5 bits;  conditional E-value: 0.0019
       PPR_3  14 dvvtYthLLtayanagnkklalevlermkkk 44 
                     Yt  L +y+++gn++ +  + ++m++ 
  EEA21698.1 690 TEFHYTLVLYGYVQQGNRDMIYLINKEMEQR 720
                 5568************************985 PP

>> PPR_long  Pentacotripeptide-repeat region of PRORP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.0     0.032        71      91     152 ..     397     458 ..     338     469 .. 0.76
   2 !   12.6   0.0   2.8e-05     0.063      58     150 ..     518     609 ..     489     618 .. 0.74
   3 !   10.2   0.0   0.00015      0.34      96     178 ..     590     673 ..     584     688 .. 0.84
   4 !    8.3   0.0    0.0006       1.4      70     152 ..     635     718 ..     620     721 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.032
                 HHHHHHHHHHHHTT-HHHHHHHHHHHHHH-S---HHHHHHHHHHHHHTT-HHHHHHHHHHHH CS
    PPR_long  91 atvtalarlaaakedgdlafelvkemekagvsPrLRsyaPaLaayckagdadkaleveehlk 152
                 + +  l  + a  +       l  e+++   +P + +y+ aL a++++gd+ k+ e  +++ 
  EEA21698.1 397 TLLHQLLGMLAEMKTHYGVQYLLDEFSHFYKQPSIGAYNYALLAFSRSGDVPKTQETFNKMV 458
                 555555555555555555666778888888899999******************99999986 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 2.8e-05
                 HC.HCSTTTHHHHHHHHHHHHHHHHHTT----HHHHHHHHHHHHHTT-HHHHHHHHHHHHHH-S---HHHHHHHHHHHHHTT-HHHHHHHHHH CS
    PPR_long  58 kaeaaseskknkalargfevfeamkakgvspnEatvtalarlaaakedgdlafelvkemekagvsPrLRsyaPaLaayckagdadkaleveeh 150
                 +a  +++  + + ++ +f+v+++m+ kgv+p   t+ +l+ ++a  +d +++ +l k  ek+  +      + +  ayc+ ++ + a    e+
  EEA21698.1 518 NALISAH-ANARNVRGAFRVWRRMQRKGVPPDWYTYGTLMGMCARLGDVENTIALCKMAEKMPGKMPVALMDTVVEAYCRNQRFQEAEDMAER 609
                 3332222.233468889***********************************99999876664333345677788888888877777666665 PP

  == domain 3  score: 10.2 bits;  conditional E-value: 0.00015
                 HHHHHHHTT-HHHHHHHHHHHHHH-S-.--HHHHHHHHHHHHHTT-HHHHHHHHHHHHHCT----HHHHHHHHHHHHHTT-HHH CS
    PPR_long  96 larlaaakedgdlafelvkemekagvs.PrLRsyaPaLaayckagdadkaleveehlkasgveleEaelaaLLkvsakagredk 178
                 ++     ++ +++a+++ ++  +  +s  r R ++ +L+++    d+d    ++ ++k +g+e +E+ +aa++   + +g+ + 
  EEA21698.1 590 VVEAYCRNQRFQEAEDMAERCLALSLSgSRTRMWNVLLYSHALRADLDSVSRIQTRMKEAGIEFDEMTYAAIMLCFVVIGQPNS 673
                 55556677889999999999988888768******************************************9988888877655 PP

  == domain 4  score: 8.3 bits;  conditional E-value: 0.0006
                 HHHHHHHHHHHHHHTT----HHHHHHHHHHHHHTT-HHHHHHHHHHHH.HH-S---HHHHHHHHHHHHHTT-HHHHHHHHHHHH CS
    PPR_long  70 alargfevfeamkakgvspnEatvtalarlaaakedgdlafelvkeme.kagvsPrLRsyaPaLaayckagdadkaleveehlk 152
                  l+++ ++ ++mk++g++  E t++a++   +  ++ + a +l + ++    ++     y  +L+ y+++g+ d  + +++ ++
  EEA21698.1 635 DLDSVSRIQTRMKEAGIEFDEMTYAAIMLCFVVIGQPNSARRLLRGLQrGRRIQATEFHYTLVLYGYVQQGNRDMIYLINKEME 718
                 467788899999999999999999999988899999999999999998345688888899999999999999999999988887 PP

>> PPR_1  PPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       1.4   3.1e+03      18      34 .]     442     458 ..     434     458 .. 0.86
   2 !    9.5   0.0   0.00035      0.78       9      34 .]     516     541 ..     514     541 .. 0.95
   3 !    8.4   0.0   0.00077       1.7       1      29 [.     543     571 ..     543     574 .. 0.89
   4 !    5.9   0.0    0.0047        11      12      29 ..     589     606 ..     588     609 .. 0.90
   5 ?   -4.2   0.3       6.4   1.4e+04       9      14 ..    1082    1087 ..    1082    1087 .. 0.94

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.4
                 HHTS-HHHHHHHHHHHH CS
       PPR_1  18 CkaGrvdeAfelfdeMe 34 
                  + G+v +  e f++M+
  EEA21698.1 442 SRSGDVPKTQETFNKMV 458
                 5899999999******5 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00035
                 HHHHHHHHHHHTS-HHHHHHHHHHHH CS
       PPR_1   9 TYNtLIdGlCkaGrvdeAfelfdeMe 34 
                 ++N LI++   a +v  Af+++++M+
  EEA21698.1 516 CWNALISAHANARNVRGAFRVWRRMQ 541
                 59***********************5 PP

  == domain 3  score: 8.4 bits;  conditional E-value: 0.00077
                 SS----HHHHHHHHHHHHHTS-HHHHHHH CS
       PPR_1   1 kGlkPdvvTYNtLIdGlCkaGrvdeAfel 29 
                 kG+ Pd +TY tL   + + G+v+  + l
  EEA21698.1 543 KGVPPDWYTYGTLMGMCARLGDVENTIAL 571
                 79********************9976655 PP

  == domain 4  score: 5.9 bits;  conditional E-value: 0.0047
                 HHHHHHHHTS-HHHHHHH CS
       PPR_1  12 tLIdGlCkaGrvdeAfel 29 
                 t++ ++C++ r  eA+++
  EEA21698.1 589 TVVEAYCRNQRFQEAEDM 606
                 8999***********987 PP

  == domain 5  score: -4.2 bits;  conditional E-value: 6.4
                  HHHHHH CS
       PPR_1    9 TYNtLI 14  
                  TYN +I
  EEA21698.1 1082 TYNVMI 1087
                  9***99 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.0   0.0         1   2.2e+03       5      18 ..     168     181 ..     166     214 .. 0.83
   2 ?   -3.4   0.0         8   1.8e+04      11      30 ..     228     247 ..     228     248 .. 0.83
   3 ?    4.6   0.0     0.032        71       3      31 ..     516     544 ..     514     557 .. 0.85
   4 !    8.3   0.0    0.0021       4.7       8      31 ..     591     614 ..     583     628 .. 0.78
   5 ?   -2.8   0.0       7.5   1.7e+04       7      25 ..     848     866 ..     844     874 .. 0.73

  Alignments for each domain:
  == domain 1  score: -0.0 bits;  conditional E-value: 1
      TPR_14   5 lalaeallalGdpd 18 
                 +++a++l+ +Gd d
  EEA21698.1 168 YDRAWVLWKQGDQD 181
                 68899999999866 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 8
      TPR_14  11 llalGdpdeAiallrralal 30 
                 ll++G + + ++l+++a+a+
  EEA21698.1 228 LLEAGHLPAVERLCDDAVAK 247
                 56789999999999999987 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.032
      TPR_14   3 allalaeallalGdpdeAiallrralala 31 
                  + al +a++++++ ++A ++ rr+ +++
  EEA21698.1 516 CWNALISAHANARNVRGAFRVWRRMQRKG 544
                 5889********************97765 PP

  == domain 4  score: 8.3 bits;  conditional E-value: 0.0021
      TPR_14   8 aeallalGdpdeAiallrralala 31 
                 +ea+ ++++++eA+++++r+lal 
  EEA21698.1 591 VEAYCRNQRFQEAEDMAERCLALS 614
                 78999**************98864 PP

  == domain 5  score: -2.8 bits;  conditional E-value: 7.5
      TPR_14   7 laeallalGdpdeAiallr 25 
                 l e++ + G++++  ++ +
  EEA21698.1 848 LMEVYSQDGNFEAVQKCWD 866
                 7789999999998766555 PP

>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.2   6.9e-05      0.15      10      31 ..     592     613 ..     585     614 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 6.9e-05
      TPR_10  10 nalrqrgrydeAealleealai 31 
                  a+++ +r++eAe+++e++la+
  EEA21698.1 592 EAYCRNQRFQEAEDMAERCLAL 613
                 69******************96 PP

>> SHQ1  SHQ1 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.2    0.0001      0.23      35     114 ..     316     400 ..     299     424 .. 0.76
   2 ?   -3.0   0.0       2.1   4.6e+03      95     124 ..     812     842 ..     811     853 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.0001
        SHQ1  35 ltlvdiLfayaYdqretegeknvESawtigkLspqlsfldef...sslkevviasvr..RsltYPlyRnfeLaekvlkdvykiLr 114
                 l+l + ++ +++++ +   +  vESa ++ + s++l fl+++     +++ +  + r  R+ +  lyRnf     + k + ++L+
  EEA21698.1 316 LQLASDVLDFVFESDKIMRDMIVESALSLTRRSANLGFLQQShynRAIQTLLKIGKRasRVFSMVLYRNFRWHLSTCKPTKTLLH 400
                 55555577899******************************5442555555555544225566779****988888877777765 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 2.1
        SHQ1  95 lyRnfeLaek.vlkdvykiLrggkrlvlkcL 124
                 +yR  +L+ +   kd++  L + kr+v+ +L
  EEA21698.1 812 MYRRTQLMLReYAKDLQASLASDKRTVVPSL 842
                 6888887754388999999****99998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1254 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       481  (0.026828); expected 358.6 (0.02)
Passed bias filter:                      429  (0.0239277); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.80u 0.28s 00:00:01.08 Elapsed: 00:00:00.46
# Mc/sec: 8251.83
//
Query:       EEA21699.1  [L=600]
Description: signal recognition particle, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   9.2e-190  632.3   0.5     1e-189  632.2   0.5    1.0  1  SRP68     RNA-binding signal recognition particle 68
     0.0052   15.6   0.0       0.01   14.7   0.0    1.4  1  BRO1      BRO1-like domain


Domain annotation for each model (and alignments):
>> SRP68  RNA-binding signal recognition particle 68
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  632.2   0.5  1.2e-193    1e-189       1     559 []      15     573 ..      15     573 .. 0.97

  Alignments for each domain:
  == domain 1  score: 632.2 bits;  conditional E-value: 1.2e-193
                 TSSS-HHHHHHHHHHHHHHHHHHTT--SS----SS-TT.--HHHHHH-THHHHHHHHHHHHHHHHHHHHHHHTCTT..TTTS-HHHHHHHHHHHHHHHH CS
       SRP68   1 LrhgDYqrYrqyltrrLrrlRkkLkfatgkrgkyakka.itaeqvatdvrylhllLltaERaWAyamalKaehsad..kkgitgrkRshivsRLrKAak 96 
                 L+ gDY++Yr++ +rrL+++RkkL+ +t+k++k+++   +t e+va+d + +hll+l+aERaWA+am++Ka hsad  +kgi g +R+hi+sRL+KA +
  EEA21699.1  15 LLSGDYNTYRAQTSRRLHTIRKKLGHTTPKGRKFNAEVpVTSEDVASDTQAAHLLILSAERAWAQAMHMKAVHSADpsAKGIMGPTRRHIISRLNKASR 113
                 789**********************************99************************************************************ PP

                 HHHHHHHHHHC.S.-S--HHHHHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHHHHHH.TTTHHHHHHHTHH...HHHHHHHHHCT-SSS--H CS
       SRP68  97 lAeeLvellse.assgadertkLEarAYaallrGallfekqqWekalesyskaraiyeaLakvt.seefkdllsetveelePsiRYcaYqlkeprtaps 193
                 +Ae+Lv++l++ + sga++ + LEarAY+all+G l++ekq+W+++l+++s ar+iy+aL+++  +e +++++s t++   Ps+RY+aYqlk++r++p 
  EEA21699.1 114 YAERLVSVLQDqSLSGASDIDLLEARAYLALLSGGLHMEKQKWDQCLQQFSLARIIYSALSQKErKEAYREIISVTID---PSLRYAAYQLKISRNKPL 209
                 ******************************************************************************...****************** PP

                 HHHHHHHHHH-.XXXXXXXXXXXXXXXXXXXXXXXX.X........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX...XX..XXXXXXXXXXX CS
       SRP68 194 etiarkafekaendllqskiekldpealkeqaaskssk........apseitWrgrevkvedakirlalaavqeakaelee...es.kssakekaaaYd 280
                 +++a++ f+++  +++++++ek+dp++l e+aa ++ +        +p++itWr+r+v++eda+i++alaa+++a+++l++   e+ ++s++ekaaaYd
  EEA21699.1 210 PSLAIERFPGD--NNVRAELEKVDPNCLIEDAAGTT-RladgeiekLPETITWRSRSVPIEDASIAQALAAATAAESKLSAflqERpSASPREKAAAYD 305
                 ********998..68****************99754.4599*****************************************974478*********** PP

                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXX......XXXXXXXXXXXXXXX CS
       SRP68 281 kvLiasqDavdatkqaidelekegvaqsdkrmqslqilrtavnyeklswrieRnrvlvgeadgklaeessakskkkkk......egrklakleElvrLy 373
                 +v++asq++vdatk+aid+l +egv+ +d r+q+lq++rtavny ++swr++Rnrvl ge+dg l + +++k+++++k       g+ l++l+E+v+Ly
  EEA21699.1 306 NVILASQEIVDATKTAIDDLTNEGVDRGDRRIQALQVTRTAVNYSLVSWRVGRNRVLSGEHDGLLLDGEQTKTDERRKtvrqesGGKILSQLREKVALY 404
                 ******************************************************************99999999888459999999************* PP

                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       SRP68 374 dallqslesikelpgvaadeelaeeleakkayfrAlrclyiarshalaskyaeAlALlkrAlelaeealeelsksdakskpeslevlleelqeLadelk 472
                 d++lqsl+ ++elpgva d+++++eleak++yfrAlrc++i+rsh++++++++AlAL++r++ela++ +++ +  +a+s p++l+v++ee+++La++ +
  EEA21699.1 405 DSVLQSLDFVQELPGVAGDTDFVDELEAKRNYFRALRCFAIGRSHSFQENTKNALALFSRSSELATTIQKSGKGITANSGPPRLDVSAEEMDFLATTSQ 503
                 ****************************************************************************9888******************* PP

                 XXXXXXXXXXXX..XXXXX.............XXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       SRP68 473 gelqrarAlveleelkkeeeslkkslsklslsekaaakkkkkpllerLdeypssggevdlknlvelPPklepvpvKPiflDvAlNyI 559
                 g ++++r+lv l++l++ +             ++ a  + + pl+er+dey  ++   +l+nlv++PPk++++pvKP+flDvA+NyI
  EEA21699.1 504 GFEAKYRGLVSLDKLSETK-------------QDPA--RLQLPLIERMDEYAVES--LNLTNLVPFPPKMRAIPVKPLFLDVAWNYI 573
                 *************987777.............3443..7899**********976..6****************************9 PP

>> BRO1  BRO1-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   1.1e-06      0.01     203     347 ..     392     542 ..     378     568 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.1e-06
                 XXXXXXXXXXXXXXXXXXXXXX.......XXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.......... CS
        BRO1 203 sliaKlaaqvaelYeealealkkselidekeevlkkl.ldksWikhvqvKashfkAlaqyrqalaaeeakkyGeeiarlqkAlellkea.......... 290
                 +++++l ++va lY+++l++l      +e    l ++  d+++++ +++K ++f+Al ++  + +   +++  +++a + +++el++++          
  EEA21699.1 392 KILSQLREKVA-LYDSVLQSLDF---VQE----LPGVaGDTDFVDELEAKRNYFRALRCFAIGRSHSFQENTKNALALFSRSSELATTIqksgkgitan 482
                 56677766665.89*****9943...222....4446689************************999**********************5555555555 PP

                 ...X..................XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        BRO1 291 ...lkskkaeel.......ledlkglkdvveeklkeaekDNdlIYheevPsesslpeikkaslvkai 347
                                     + l+++++ +e+k++ +   + l + ++ P+  +lp i++++ + + 
  EEA21699.1 483 sgpP-------RldvsaeeMDFLATTSQGFEAKYRGLVSLDKLSETKQDPARLQLPLIERMDEYAVE 542
                 5551.......04445444788999999999999999999999999999999999998888844443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (600 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       551  (0.0307323); expected 358.6 (0.02)
Passed bias filter:                      434  (0.0242066); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.32s 00:00:00.89 Elapsed: 00:00:00.46
# Mc/sec: 3888.37
//
Query:       EEA21700.1  [L=522]
Description: signal recognition particle, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.5e-156  522.0   0.1     3e-156  521.7   0.1    1.0  1  SRP68     RNA-binding signal recognition particle 68
     0.0042   15.9   0.0     0.0077   15.1   0.0    1.3  1  BRO1      BRO1-like domain


Domain annotation for each model (and alignments):
>> SRP68  RNA-binding signal recognition particle 68
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  521.7   0.1  3.4e-160    3e-156      71     559 .]       8     495 ..       4     495 .. 0.96

  Alignments for each domain:
  == domain 1  score: 521.7 bits;  conditional E-value: 3.4e-160
                 HTCTT..TTTS-HHHHHHHHHHHHHHHHHHHHHHHHHHC.S.-S--HHHHHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHHHHHH.TTTHHH CS
       SRP68  71 ehsad..kkgitgrkRshivsRLrKAaklAeeLvellse.assgadertkLEarAYaallrGallfekqqWekalesyskaraiyeaLakvt.seefkd 165
                  hsad  +kgi g +R+hi+sRL+KA ++Ae+Lv++l++ + sga++ + LEarAY+all+G l++ekq+W+++l+++s ar+iy+aL+++  +e +++
  EEA21700.1   8 VHSADpsAKGIMGPTRRHIISRLNKASRYAERLVSVLQDqSLSGASDIDLLEARAYLALLSGGLHMEKQKWDQCLQQFSLARIIYSALSQKErKEAYRE 106
                 577788899****************************************************************************************** PP

                 HHHHTHH...HHHHHHHHHCT-SSS--HHHHHHHHHHH-.XXXXXXXXXXXXXXXXXXXXXXXX.X........XXXXXXXXXXXXXXXXXXXXXXXXX CS
       SRP68 166 llsetveelePsiRYcaYqlkeprtapsetiarkafekaendllqskiekldpealkeqaaskssk........apseitWrgrevkvedakirlalaa 256
                 ++s t++   Ps+RY+aYqlk++r++p +++a++ f+++  +++++++ek+dp++l e+aa ++ +        +p++itWr+r+v++eda+i++alaa
  EEA21700.1 107 IISVTID---PSLRYAAYQLKISRNKPLPSLAIERFPGD--NNVRAELEKVDPNCLIEDAAGTT-RladgeiekLPETITWRSRSVPIEDASIAQALAA 199
                 *******...**************************998..68****************99754.4599****************************** PP

                 XXXXXXXXXX...XX..XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XX CS
       SRP68 257 vqeakaelee...es.kssakekaaaYdkvLiasqDavdatkqaidelekegvaqsdkrmqslqilrtavnyeklswrieRnrvlvgeadgklaeessa 351
                 +++a+++l++   e+ ++s++ekaaaYd+v++asq++vdatk+aid+l +egv+ +d r+q+lq++rtavny ++swr++Rnrvl ge+dg l + +++
  EEA21700.1 200 ATAAESKLSAflqERpSASPREKAAAYDNVILASQEIVDATKTAIDDLTNEGVDRGDRRIQALQVTRTAVNYSLVSWRVGRNRVLSGEHDGLLLDGEQT 298
                 ***********974478*****************************************************************************99999 PP

                 XXXXXXX......XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       SRP68 352 kskkkkk......egrklakleElvrLydallqslesikelpgvaadeelaeeleakkayfrAlrclyiarshalaskyaeAlALlkrAlelaeealee 444
                 k+++++k       g+ l++l+E+v+Lyd++lqsl+ ++elpgva d+++++eleak++yfrAlrc++i+rsh++++++++AlAL++r++ela++ +++
  EEA21700.1 299 KTDERRKtvrqesGGKILSQLREKVALYDSVLQSLDFVQELPGVAGDTDFVDELEAKRNYFRALRCFAIGRSHSFQENTKNALALFSRSSELATTIQKS 397
                 999888459999999************************************************************************************ PP

                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..XXXXX.............XXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXX CS
       SRP68 445 lsksdakskpeslevlleelqeLadelkgelqrarAlveleelkkeeeslkkslsklslsekaaakkkkkpllerLdeypssggevdlknlvelPPkle 543
                  +  +a+s p++l+v++ee+++La++ +g ++++r+lv l++l++ +             ++ a  + + pl+er+dey  ++   +l+nlv++PPk++
  EEA21700.1 398 GKGITANSGPPRLDVSAEEMDFLATTSQGFEAKYRGLVSLDKLSETK-------------QDPA--RLQLPLIERMDEYAVES--LNLTNLVPFPPKMR 479
                 *****9888********************************987777.............3443..7899**********976..6************* PP

                 XXXXXXXXXXXXXXXX CS
       SRP68 544 pvpvKPiflDvAlNyI 559
                 ++pvKP+flDvA+NyI
  EEA21700.1 480 AIPVKPLFLDVAWNYI 495
                 ***************9 PP

>> BRO1  BRO1-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   8.5e-07    0.0077     203     347 ..     314     464 ..     300     490 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 8.5e-07
                 XXXXXXXXXXXXXXXXXXXXXX.......XXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.......... CS
        BRO1 203 sliaKlaaqvaelYeealealkkselidekeevlkkl.ldksWikhvqvKashfkAlaqyrqalaaeeakkyGeeiarlqkAlellkea.......... 290
                 +++++l ++va lY+++l++l      +e    l ++  d+++++ +++K ++f+Al ++  + +   +++  +++a + +++el++++          
  EEA21700.1 314 KILSQLREKVA-LYDSVLQSLDF---VQE----LPGVaGDTDFVDELEAKRNYFRALRCFAIGRSHSFQENTKNALALFSRSSELATTIqksgkgitan 404
                 56677766665.89*****9943...222....4446689************************999**********************5555555555 PP

                 ...X..................XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        BRO1 291 ...lkskkaeel.......ledlkglkdvveeklkeaekDNdlIYheevPsesslpeikkaslvkai 347
                                     + l+++++ +e+k++ +   + l + ++ P+  +lp i++++ + + 
  EEA21700.1 405 sgpP-------RldvsaeeMDFLATTSQGFEAKYRGLVSLDKLSETKQDPARLQLPLIERMDEYAVE 464
                 5551.......04445444889999999999999999999999999999999999998888844443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (522 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       650  (0.0362541); expected 358.6 (0.02)
Passed bias filter:                      533  (0.0297284); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.33s 00:00:00.94 Elapsed: 00:00:00.48
# Mc/sec: 3300.75
//
Query:       EEA21701.1  [L=534]
Description: cytochrome P450 sterol C-22 desaturase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-53  182.4   0.0    2.7e-53  181.4   0.0    1.4  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  181.4   0.0   1.5e-57   2.7e-53       7     433 ..      72     500 ..      66     527 .. 0.82

  Alignments for each domain:
  == domain 1  score: 181.4 bits;  conditional E-value: 1.5e-57
                 HHCCHCHHHHTTTCCHHHHHHHHHHHH..-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHHHHHH CS
        p450   7 lplvgnllqlgrkeelhevlrklqkky..gpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkklRrflt 103
                 +p++g +l+       + +++k++ k   g +  + + +k vv+ s+ ++ +++++  +  f++   + +++ ++k     + +f +g+ + + R+ l+
  EEA21701.1  72 IPFMGPFLESV-----FPNFTKYKAKWnsGALSCVSVFHKFVVIASSRDLSRKIFNSPA--FVK---PCVVDAAHKLLGADNWVFLDGKAHVEFRKGLN 160
                 66666666654.....44577777776669999999999999999**********9993..555...56777777899********************* PP

                 HHHTSHSTT.THHHHHHHHHHHHHHHHHCCCCHCS..EEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCCCHHHT CS
        p450 104 ptltsfgkl.sleelveeeaedlveklrkkagess..elditellskaaldvigsilFgarfdlledeklselvkaveelssllskssvqllllfpllk 199
                   +t + +l  + +  +e+ ++  + + + + +++   +   + + ++++ +++++++g ++d   de   + +k  ++++ ++     +l++++ ++ 
  EEA21701.1 161 GLFTRH-ALsLYLPGQDEVYDRYFKHWAEVSRKNDykPVQFMPEFREFMTAISCKTFVGDHMD---DE---TVKKIADDYFLIT--AALELVNFPIIIP 250
                 ******.8878***********************9999999999****************966...55...6788888886544..5667888777888 PP

                 CCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHC..................SCSSCSHHHHHHHHC..........TTCTCT....SSSSHHHHHHH CS
        p450 200 ylptkllrklkeavkklkdlldklieerretldsa..................kksrrdfldalllak..........kekkge....sklsdeelaat 266
                 +  t++++k+ ++   +     k+  + ++ l                     k                        ++++++      ++d e+a+t
  EEA21701.1 251 FTKTWYGKKAADM---VMVEFAKCAAKSKAYLAAGgevtcimdgwiklqmesaK-------------YrekvamgipvDDSEKPasllRDFTDYEIAQT 333
                 7778888877766...44444556666666666666777777765554443322.............0333555566533333355999********** PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHC.CTTT..T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEETT.EEE-TT- CS
        p450 267 vlellfaGvdTtsstlswaLyeLaknPevqeklreEidevl.gdkr..eptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirg.ylipkGt 361
                 v+++lfa++d ts++ +w +  +a++Pe+ +k+reE  +   gd r  ++t+d+l++++y++av+kE LR++p+v   +p +++kd  i + y++pkG+
  EEA21701.1 334 VFTFLFASQDATSAACTWLFQIMADRPEILDKVREENYRLRnGD-RnaPLTMDMLESMTYTRAVVKECLRYRPPVI-MVPYMAKKDFPITDtYTVPKGS 430
                 *****************************************655.5599***************************.********************** PP

                 EEEEEHHHHHT-TTTSSSTTS--GGGGB-TTSCTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHE CS
        p450 362 evivnlyalhrdpevfpnPeeFdpeRFldekgnskrksfaflPFGaGpRnCiGerlArmelklflatlLqnF 433
                 ++i+++y   +dpe +++P++++p+R+   ++  +++   +l FG+Gp+ C+G+  A+++l  ++++   + 
  EEA21701.1 431 MIIPSVYPSTHDPEAYEDPDSYNPDRWITGTA--ESQTKNWLVFGTGPHYCLGQVYATHNLMGLIGKASMHL 500
                 ******************************98..48**********************99987776655555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (534 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       524  (0.0292264); expected 358.6 (0.02)
Passed bias filter:                      474  (0.0264376); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.64u 0.31s 00:00:00.95 Elapsed: 00:00:00.49
# Mc/sec: 3258.75
//
Query:       EEA21702.1  [L=218]
Description: Rhodanese domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.5e-13   50.0   0.0    7.7e-13   48.9   0.0    1.6  1  Rhodanese  Rhodanese-like domain


Domain annotation for each model (and alignments):
>> Rhodanese  Rhodanese-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.9   0.0   4.3e-17   7.7e-13      13     105 ..     101     205 ..      89     207 .. 0.76

  Alignments for each domain:
  == domain 1  score: 48.9 bits;  conditional E-value: 4.3e-17
   Rhodanese  13 kvallDvRppeeYek.ghIpgAvnv...........skdtlsrakkseapllelpeellel.gidnkktvvvycdgggraaaaaallkklGy.kn.vsv 96 
                 +++l+DvR+p+e ++ g IpgAv++           +++ +++     +p  e  +         +kk++++yc+ g ra+aaa+l+ ++Gy ++ + v
  EEA21702.1 101 NTILIDVREPAELAAtGIIPGAVSIplasqpdayflPAEEFKTRFGFAKPVVEATAG---AgAEGEKKEIIFYCKAGVRAQAAAQLAVQAGYdPDtLGV 196
                 345**********999*********88888877444444444444444444444444...354489*************88888877789*99888*** PP

   Rhodanese  97 ldGGfkawk 105
                 ++G++ +w+
  EEA21702.1 197 YRGSWLDWS 205
                 ********7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (218 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       441  (0.024597); expected 358.6 (0.02)
Passed bias filter:                      287  (0.0160076); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 1443.34
//
Query:       EEA21703.1  [L=1065]
Description: mitochondrial translation initiation factor IF-2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.5e-33  114.8   1.6    8.9e-33  113.5   0.0    2.6  2  GTP_EFTU     Elongation factor Tu GTP binding domain
    9.2e-20   70.7   0.0    3.9e-19   68.7   0.0    2.1  1  IF-2         Translation-initiation factor 2
    7.5e-11   42.3  10.5    1.5e-09   38.1   0.0    4.0  4  GTP_EFTU_D2  Elongation factor Tu domain 2
    1.4e-09   37.7   0.2    5.2e-09   35.9   0.2    2.0  1  GTP_EFTU_D4  Elongation factor Tu domain 4
    7.4e-07   29.3   0.2    7.9e-06   25.9   0.0    2.9  3  MMR_HSR1     50S ribosome-binding GTPase
    0.00068   19.9   0.0     0.0019   18.4   0.0    1.8  1  Roc          Ras of Complex, Roc, domain of DAPkinase
     0.0078   16.0   0.0      0.035   13.9   0.0    2.3  2  ATP_bind_1   Conserved hypothetical ATP binding protein
  ------ inclusion threshold ------
      0.074   13.0   0.5        1.2    9.0   0.4    3.0  2  RsgA_GTPase  RsgA GTPase


Domain annotation for each model (and alignments):
>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.7   2.3       6.3   1.4e+04     146     147 ..     251     252 ..     213     292 .. 0.58
   2 !  113.5   0.0     4e-36   8.9e-33       5     192 ..     475     684 ..     471     686 .. 0.82

  Alignments for each domain:
  == domain 1  score: -4.7 bits;  conditional E-value: 6.3
                 HH CS
    GTP_EFTU 146 vk 147
                  k
  EEA21703.1 251 EK 252
                 22 PP

  == domain 2  score: 113.5 bits;  conditional E-value: 4e-36
                 EEEEEESTTSSHHHHHHHHHHHTTSSCHHHHHHHHHSTHCHSHHHHHHTSCSSCEE.EEEETTCSSEEEEEEEESSSGGGHHHHHHHHHT-SEEEEEEE CS
    GTP_EFTU   5 nigiighvDhGKtTLtdrLlyktgaiskkgekaeeervlDtlkeErergiTiksaa.isleketkkylinliDtPGHvdFskevirglrvlDgavlvvd 102
                  ++i+ghvD+GKt L+d++ +++ +  ++g  ++ +      + +  ++ T  +++  s+e   k   + +iDtPGH++Fs+  +rg + +++a+lvvd
  EEA21703.1 475 ICCILGHVDTGKTKLLDKIRQTNVQEGEAGGITQ-QIGATYFPVDALKQKTAVVNQdGSFE--FKIPGLLIIDTPGHESFSNLRSRGSSLCNIAILVVD 570
                 69******************99999888877775.55566666666666666665515666..99********************************** PP

                 TTTBSTHHHHHHHHHHHHTTTEEEEEEESCGST...........HHHHHHHHHHHHHHHHHH...........HHHHHHHHHTTT............TT CS
    GTP_EFTU 103 aveGvepqteevlrlalkegvpiivfiNKmDrl...........kaelkeiveevkqklsrk...........eeklekygekge............ke 167
                 +++G epqt e +rl++++++p+iv++NK+Drl           +++l ++ + v ++++++                                   ++
  EEA21703.1 571 IMHGLEPQTLESMRLLRDRKTPFIVALNKIDRLygwkkidnngfQESLAMQSKGVINEFRSRveatklafaeqG----------FnselywenksmaRN 659
                 *************************************9999988777777777777777555555544444331..........144466666668799 PP

                 EEEEEEBTTTTBTHHHHHHHHHHHS CS
    GTP_EFTU 168 vpvvfgSalkgegvktllealvell 192
                 v++v++Sa +geg+ ++l+ l++l+
  EEA21703.1 660 VSLVPTSAHTGEGIPDMLKLLTTLT 684
                 ****************999998765 PP

>> IF-2  Translation-initiation factor 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.7   0.0   1.7e-22   3.9e-19       2     104 ..     810     912 ..     809     913 .. 0.89

  Alignments for each domain:
  == domain 1  score: 68.7 bits;  conditional E-value: 1.7e-22
                 CCHHHCCCSCSSCCEEEEEESSHHHHHHHHHHHHCTT.SSTEEEECEEEESSB-HHHHHHHHH......ST.EEEEEESSSCTHHHHHCCCCCTSEEEE CS
        IF-2   2 eelfeeikeegkelnviikaDvqGsleAlkeaLekleseevkvkvihsgvGaitesDvelasa......sn.aiiigFnvkvskkakklaekegvkirl 93 
                 e+l+++++  +++ +v ++a++ GsleAl e+L+       k++v + ++G++ ++Dv+la +      ++ a++++F+vkv+k+a++ a++ gvki++
  EEA21703.1 810 ENLLSKVS--KDQRGVSVQASTLGSLEALLEFLRVS-----KIPVSNISIGPVFKRDVMLAGTmlekglKEyAVMLCFDVKVDKEAQAYADDVGVKIFT 901
                 56667777..35779*******************97.....7*******************99776554227*************************** PP

                 ESSHHHHHHHH CS
        IF-2  94 ynvIYkliddv 104
                 +++IY+l+dd+
  EEA21703.1 902 ADIIYHLFDDF 912
                 *********97 PP

>> GTP_EFTU_D2  Elongation factor Tu domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   1.9       7.8   1.7e+04      28      44 ..     252     268 ..     215     291 .. 0.65
   2 ?   -3.3   0.0       5.6   1.3e+04      24      40 ..     482     498 ..     478     525 .. 0.49
   3 !   38.1   0.0   6.5e-13   1.5e-09       1      72 [.     712     788 ..     712     790 .. 0.96
   4 !    9.5   0.1   0.00056       1.3       3      62 ..     950    1011 ..     949    1028 .. 0.81

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 7.8
                  SEEEEEEEEEEEEETEE CS
  GTP_EFTU_D2  28 kkeivtrissletfhed 44 
                  kk++  r ++ e+++e+
   EEA21703.1 252 KKKEEARQRKKEKEKEK 268
                  33344444444444444 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 5.6
                  TCTTSEEEEEEEEEEEE CS
  GTP_EFTU_D2  24 ndtskkeivtrisslet 40 
                  +dt+k++ + +i+++ +
   EEA21703.1 482 VDTGKTKLLDKIRQTNV 498
                  45544443333333322 PP

  == domain 3  score: 38.1 bits;  conditional E-value: 6.5e-13
                  EEEEEEEEEESEEETTEEEEEEC.TCTTSEEEEEEEEEEEEETEEESEE..........ETTSEEEEEEEESSCCSGSSTTCE CS
  GTP_EFTU_D2   1 GtvalgrvysGtlkkGdevrilg.ndtskkeivtrissletfhededea..........vaganaGvivaikgledaiivGdt 72 
                  Gt++++++ +G+l++Gd+++++g n+    +i t i++l+t+ ++++e+          ++ a+ Gv++a+ +le+a i+G+ 
   EEA21703.1 712 GTTIDVVLSNGILREGDRIVLCGlNG----PISTNIRALLTP-APLKELrlksqyvhnkEVKAALGVKIAANDLEHA-IAGSR 788
                  9**********************998....999*********.99*******************************8.99975 PP

  == domain 4  score: 9.5 bits;  conditional E-value: 0.00056
                   EEEEEEEESEEETTEEEEEEC.TCTTSEE..EEEEEEEEEEETEEESEEETTSEEEEEEEESS CS
  GTP_EFTU_D2    3 valgrvysGtlkkGdevrilg.ndtskke..ivtrissletfhededeavaganaGvivaikg 62  
                   v+++ v++G l+    + +++ n  ++ke  +++r+ss+e+ h+  + + + ++  v v+i+g
   EEA21703.1  950 VVGVDVVEGSLRLLTPIAVVKqNAAGQKEiiQLGRVSSIERDHKAIQ-VCKRGQPSVAVKIDG 1011
                   79999*************************************99544.455555555555555 PP

>> GTP_EFTU_D4  Elongation factor Tu domain 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.9   0.2   2.3e-12   5.2e-09      11      86 .]     941    1028 ..     934    1028 .. 0.81

  Alignments for each domain:
  == domain 1  score: 35.9 bits;  conditional E-value: 2.3e-12
                   EEEETCCCEEEEEEEEEEEEETT-EE..E..ETTE.....EEEEEEEEEETTEEESEEETT-.EEEEEEESS-...TTTS--TT-EEE CS
  GTP_EFTU_D4   11 vvfrrsdpaivGvevlgGvikpgvkl..i..kedGr....evGeilqiqdkgkkleeakaGq.evaisiegki...vGrqikegdily 86  
                    vf ++dp++vGv+v++G ++   ++  +  ++ G+    ++G++++i++ +k++++ k+Gq +va+ i+g+     Grq++e d+ly
   EEA21703.1  941 AVFNKKDPIVVGVDVVEGSLRLLTPIavVkqNAAGQkeiiQLGRVSSIERDHKAIQVCKRGQpSVAVKIDGANqpsYGRQLEESDTLY 1028
                   59****************999665541142234566333359*******************967******9755568**********9 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.9   0.0   3.5e-09   7.9e-06       2     114 .]     476     599 ..     475     599 .. 0.79
   2 ?   -3.0   0.0       3.3   7.4e+03      30      78 ..     711     769 ..     700     813 .. 0.56
   3 ?   -1.4   0.1       1.1   2.4e+03      75     103 ..     901     925 ..     882     945 .. 0.56

  Alignments for each domain:
  == domain 1  score: 25.9 bits;  conditional E-value: 3.5e-09
                 EEEEESTTSSHHHHHHHHHTSTEEESSSTTSSSSE..EEEEEE.ETTEE.................EEEEECGGCSSHHHHHHHHHHHHHHHHC.TSEE CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltgekaivsdkpgtTrdi..negrvk.lkgke.................ielvDtpGliegaseekglgkaflalee.adli 79 
                 ++i+G+  +GK+ L+ ++ +++++ ++  g T++i  +++ v+ l + +                 + ++DtpG  e      ++++   +  + ++++
  EEA21703.1 476 CCILGHVDTGKTKLLDKIRQTNVQEGEAGGITQQIgaTYFPVDaL-K-QktavvnqdgsfefkipgLLIIDTPG-HE------SFSNLRSRGSSlCNIA 565
                 689*******************************95555555531.2.235677777788888888********.54......33333333333489** PP

                 EEEEETTTTCSHHHHHHHHHHHHHTTSEEEEEEES CS
    MMR_HSR1  80 llvvdaseeklkpldeeleelleeakkplilvlnk 114
                 +lvvd+  ++l+p+  e  +ll+++k p+i++lnk
  EEA21703.1 566 ILVVDIM-HGLEPQTLESMRLLRDRKTPFIVALNK 599
                 *****99.7799999999999999**********8 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 3.3
                 TTSSSSEEEEEEEETT.EEEEEEECGGC.............SSHHHHHHHHHHHHHHHHCTSE CS
    MMR_HSR1  30 pgtTrdinegrvklkg.keielvDtpGl.............iegaseekglgkaflaleeadl 78 
                  gtT+d++  +  l++ ++i+l+ + G              +    +e +l+ ++  ++e+++
  EEA21703.1 711 LGTTIDVVLSNGILREgDRIVLCGLNGPistniralltpapL----KELRLKSQYVHNKEVKA 769
                 678888765554433336777777777312222222221111....22245555554444443 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 1.1
                 CTSEEEEEEETTTTCSHHHHHHHHHHHHH CS
    MMR_HSR1  75 eadlillvvdaseeklkpldeeleellee 103
                  ad+i +++d  ++       el e ++e
  EEA21703.1 901 TADIIYHLFDDFTK----HMAELTEQRKE 925
                 48999999994422....22333333322 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.0   8.6e-07    0.0019       3     119 ..     477     601 ..     476     602 .. 0.72

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 8.6e-07
                 EEESSTTSSHHHHHHCHCT-CCC-EE....ETTTTEEEEEEECGGSGGCT.TBT...TTTCEEEEEEEE-SGGCTTTT-HHHHCTSCEEEEEEEGHHHH CS
         Roc   3 vlvGdsgvGKtsllkrfvedkfseke....kstigvdfltkevtkikgve.ndk...kvkkvklniWDtaGqerfrslhplylreaalailvydsrsse 93 
                 +++G   +GKt+ll+++ + +++e e    ++ ig++++  ++ k k+   n++   + k   l i Dt G+e f++l++   +  ++ailv+d  +  
  EEA21703.1 477 CILGHVDTGKTKLLDKIRQTNVQEGEaggiTQQIGATYFPVDALKQKTAVvNQDgsfEFKIPGLLIIDTPGHESFSNLRSRGSSLCNIAILVVDIMHGL 575
                 699*******************988633336889999988666555543313330012233346899***************************76543 PP

                 CHHHHHHHHHHHCS.SS-EEEEEE-TT CS
         Roc  94 nlkeWlkelkkvag.kspvilvgnkiD 119
                 +  + l++++  ++ k+p+i+  nkiD
  EEA21703.1 576 EP-QTLESMRLLRDrKTPFIVALNKID 601
                 33.446666666552668999999999 PP

>> ATP_bind_1  Conserved hypothetical ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   0.0   1.5e-05     0.035      63     188 ..     508     622 ..     478     686 .. 0.70
   2 ?   -4.0   0.0       4.5     1e+04     184     207 ..     913     939 ..     902     965 .. 0.51

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.5e-05
  ATP_bind_1  63 gpngalvvaleflresldwldeeleke.ed.dyllfDtPGQielfthseslakiveeLesefalvvvyLvDsqrltdptkfisgllsalsamlrlelPh 159
                 ++ ga+ + ++ l+++   ++++ + e +   +l++DtPG   + ++++ ++        +   +++ +vD     +p ++ s+     + +   ++P+
  EEA21703.1 508 QQIGATYFPVDALKQKTAVVNQDGSFEfKIpGLLIIDTPGHESFSNLRSRGS--------SLCNIAILVVDIMHGLEPQTLESM-----RLLRDRKTPF 593
                 55689999999999999888666644433358********************........666788899999988888887777.....77889***** PP

  ATP_bind_1 160 vvvlnkfDllkeklekeleffedvealsl 188
                 +v+lnk+D l   ++ + + f++  a++ 
  EEA21703.1 594 IVALNKIDRLYGWKKIDNNGFQESLAMQS 622
                 ********987445555555554433333 PP

  == domain 2  score: -4.0 bits;  conditional E-value: 4.5
  ATP_bind_1 184 ealslllekee...ekykklaeaiael 207
                  ++++ l++++   +k++  + ++ ++
  EEA21703.1 913 TKHMAELTEQRkeeSKMHAVFPCVLKT 939
                 333322222222334444444444444 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.4   0.00056       1.2      63     164 ..     435     551 ..     426     554 .. 0.60
   2 ?   -1.2   0.0      0.72   1.6e+03      20      59 ..     566     603 ..     557     620 .. 0.74

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00056
                  HHHHHHHHHHHHTTSEEEE--TTTH..TTHHHHHHHCTTSEEEEECSTTSSHHHHHHHHCTT.........-----S--------------SEE...E CS
  RsgA_GTPase  63 eeleelkeelealgyevllvsaktk..egleelkellkdktsvlvGqSGvGKStLinallpe.........lelktgevseklgrGkhTTtave...l 146
                  ee++++++++++   e    ++k++  + +++ k++l++ +++++G+   GK+ L+++++++          ++++g++    +  k  T  v+    
   EEA21703.1 435 EEATATQKAIAQRKAEAAERRKKQHeeALAARSKDNLRSPICCILGHVDTGKTKLLDKIRQTnvqegeaggITQQIGATYFPVDALKQKTAVVNqdgS 532
                  3345555555555555555555544103345667899999********************98566666666455555554444444444443331222 PP

                  ..EEETTTEEEESS-SSSS- CS
  RsgA_GTPase 147 ..lelaegglliDtPGfrel 164
                    ++++ g l+iDtPG +++
   EEA21703.1 533 feFKIP-GLLIIDTPGHESF 551
                  124444.7778888887766 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.72
                  EEEEESTTTT--HHHHHHHHHHHHHTT-EEEEEEE-GGG- CS
  RsgA_GTPase  20 livvslkepelslnlldrfLvlaeekgiepvivlnKiDll 59 
                  ++vv +  + l++++l+  + l+ +++ + +++lnKiD l
   EEA21703.1 566 ILVVDIM-HGLEPQTLES-MRLLRDRKTPFIVALNKIDRL 603
                  5555555.6667777764.46678889999*******976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1065 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3324  (0.185398); expected 358.6 (0.02)
Passed bias filter:                      935  (0.0521501); expected 358.6 (0.02)
Passed Vit filter:                       412  (0.0229795); expected 17.9 (0.001)
Passed Fwd filter:                       190  (0.0105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 3.08u 0.42s 00:00:03.50 Elapsed: 00:00:00.73
# Mc/sec: 4390.99
//
Query:       EEA21704.1  [L=416]
Description: Spo7-like protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      5e-87  291.0   0.2      5e-87  291.0   0.2    1.4  2  Spo7         Spo7-like protein
  ------ inclusion threshold ------
      0.045   14.1   0.1         15    5.9   0.0    2.5  2  DUF1772      Domain of unknown function (DUF1772)
          5    7.9  10.1        7.5    7.3   9.0    1.8  1  Edc3_linker  Linker region of enhancer of mRNA-decapping prot


Domain annotation for each model (and alignments):
>> Spo7  Spo7-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  291.0   0.2   8.4e-91     5e-87       1     220 [.      56     270 ..      56     271 .. 0.90
   2 ?   -3.2   0.1      0.78   4.7e+03     173     173 ..     323     323 ..     289     368 .. 0.50

  Alignments for each domain:
  == domain 1  score: 291.0 bits;  conditional E-value: 8.4e-91
        Spo7   1 sspskiyrnLLiLEesLraqalelrarrrkytlflllLalviafflyalflapredgsgvggsvywvvevvekvlliggvvTlvLfwlsGeyertivip 99 
                 ssp++iy+nLLiLE+sLraq+l+lr+rrr++t+flllLal+ia+f+yalf++predgsgvggsvyw+ve++ekv+++gg+vT       G++er++++p
  EEA21704.1  56 SSPPQIYLNLLILESSLRAQYLALRERRRQNTFFLLLLALWIAYFFYALFMRPREDGSGVGGSVYWMVETAEKVAFMGGIVT-------GQWERGMRWP 147
                 89******************************************************************************96.......********** PP

        Spo7 100 rrflsvtNrgLRqfNvklvkvkrslleelldllavllkvgllsesekssvflvevkirsqpri...asalrekekearla...edlapgaddvkllLlp 192
                 rr+++v+NrgLR++N+k+v++++++++ell+ll+++++++ l++s+  ++++ve++++ +++    +s++++++++   a   edlapg+d++kllLlp
  EEA21704.1 148 RRWFAVANRGLRGMNTKIVLIRGPWWKELLSLLSFIFPYSSLFQSP-KNFQYVELHSSEKRAArqhHSVHDHDSDS---AfieEDLAPGGDYIKLLLLP 242
                 *****************************************99885.77888885444333331223333333334...2566**************** PP

        Spo7 193 kafspefRegweiYRaefwerenerrrk 220
                 kafspefRe+w++YRa++we+enerr++
  EEA21704.1 243 KAFSPEFRENWDEYRADYWEKENERRAQ 270
                 **************************97 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 0.78
        Spo7 173 a 173
                 a
  EEA21704.1 323 A 323
                 0 PP

>> DUF1772  Domain of unknown function (DUF1772)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.1    0.0026        15      41      89 ..      65     110 ..      50     142 .. 0.72
   2 ?    5.9   0.0    0.0025        15      63     105 ..     172     211 ..     167     299 .. 0.75

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0026
     DUF1772  41 plallsalafaylaaraasrgarllylaaaallllsivpyTllvmvPtN 89 
                 +l l s+l + yla r ++r++   +l++a+  +    ++ +l+m+P +
  EEA21704.1  65 LLILESSLRAQYLALRERRRQNTFFLLLLALW-I--AYFFYALFMRPRE 110
                 45556666667999777666666666443333.3..3567888898865 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0025
     DUF1772  63 rllylaaaallllsivpyTllvmvPtNnkLaalkeedakeked 105
                 ++   ++++l +  i+py+ l+  P N++  +l +++++++++
  EEA21704.1 172 WWKE-LLSLLSF--IFPYSSLFQSPKNFQYVELHSSEKRAARQ 211
                 5555.4466666..9************8877774222222222 PP

>> Edc3_linker  Linker region of enhancer of mRNA-decapping protein 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   9.0    0.0013       7.5       8      74 ..     314     380 ..     306     386 .. 0.78

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0013
  Edc3_linker   8 ksssapqailrradvksqevvtsPqqssksyvdrhldalkqsksfrrrhnsgssssRganqstpkks 74 
                  ++++++    rr +  + ++      s  s +++ + + ++++++rr++    sssRg+   tp+ s
   EEA21704.1 314 SVAKTQEGRARRNTRSNSQSLHTRGLSRSSTPESTISTATEPQGHRRKKSIRPSSSRGPSPLTPQVS 380
                  4555555566666666666666667777788999*****************************9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (416 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1236  (0.0689386); expected 358.6 (0.02)
Passed bias filter:                      563  (0.0314016); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.56u 0.30s 00:00:00.86 Elapsed: 00:00:00.44
# Mc/sec: 2829.51
//
Query:       EEA21705.1  [L=504]
Description: alpha/beta hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-21   77.6   0.0    4.3e-20   72.4   0.0    2.5  2  Abhydrolase_1    alpha/beta hydrolase fold
    2.6e-17   62.9   0.0    3.1e-16   59.4   0.0    2.1  2  Hydrolase_4      Serine aminopeptidase, S33
      3e-17   63.9   6.6    3.4e-16   60.5   6.6    2.2  1  Abhydrolase_6    Alpha/beta hydrolase family
    4.1e-06   26.3   0.0    8.9e-06   25.2   0.0    1.5  1  DUF915           Alpha/beta hydrolase of unknown function (DU
    4.5e-05   23.2   0.0     0.0001   22.0   0.0    1.6  1  Esterase         Putative esterase
     0.0014   18.6   0.0     0.0034   17.3   0.0    1.6  2  Abhydrolase_3    alpha/beta hydrolase fold
     0.0018   17.2   0.0     0.0028   16.6   0.0    1.3  1  Chlorophyllase2  Chlorophyllase enzyme
     0.0026   17.4   0.0     0.0063   16.1   0.0    1.6  1  LIDHydrolase     Lipid-droplet associated hydrolase
     0.0073   16.1   0.0      0.026   14.3   0.0    1.8  2  Abhydrolase_5    Alpha/beta hydrolase family
     0.0083   14.9   0.0      0.013   14.2   0.0    1.2  1  Ndr              Ndr family
      0.009   16.1   0.7      0.077   13.1   0.7    2.4  1  Thioesterase     Thioesterase domain
  ------ inclusion threshold ------
      0.018   14.8   0.0       0.12   12.1   0.0    2.0  2  PGAP1            PGAP1-like protein
      0.024   13.7   0.0      0.037   13.0   0.0    1.3  1  Chlorophyllase   Chlorophyllase
      0.033   14.0   0.0        2.8    7.7   0.0    2.6  3  Abhydrolase_2    Phospholipase/Carboxylesterase


Domain annotation for each model (and alignments):
>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.4   0.0   3.4e-23   4.3e-20       3     118 ..     155     279 ..     153     287 .. 0.88
   2 ?    2.6   0.0      0.07        89     199     227 ..     410     432 ..     332     481 .. 0.61

  Alignments for each domain:
  == domain 1  score: 72.4 bits;  conditional E-value: 3.4e-23
                    EEEE-STTTCGGGGTTGHHHHHHHHT.TSEEEEEEETTSTTSSSTTTGB.........CHHSHHHHHHHHHHHHHHCTTSSEEEEEETHHHHHHHH CS
  Abhydrolase_1   3 lvilhGlpgssdvwaerglapaLakd.gfdvillDlrGvgySspapacin........ddygtasvaddldrildalgddkltlvGhSmGGmiala 89 
                    lv+lhG++++++ +++   ++ L+++ g+++++lDl+G g+S+++p +i         ++ +++ + d l+  + + +++++tl+GhSmGG ia+a
     EEA21705.1 155 LVMLHGYGAGLGFFYR--NFEPLSRAkGWHLYALDLLGMGRSTRPPFKIKasdrqeaiTEAENW-FIDALEEWRIKRKIERFTLMGHSMGGYIAAA 247
                    8***************..9999*9999**************************96555555555.555555559999******************* PP

                    HHHHHGGGEEEEEEESE...CSSCCHHHHHHH CS
  Abhydrolase_1  90 yaaeyperVkalvllga...idpaaslieaqr 118
                    ya++yp r ++l+l+++   ++++++ +ea++
     EEA21705.1 248 YALKYPGRLNKLILVSPvgiPEDPYAVNEAMP 279
                    *****************998777777777765 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.07
                    HHHHHHHCTHHHHSEEEEEEETTCSSSCH CS
  Abhydrolase_1 199 klllrlrelknvlaptlvisgtsDplvpp 227
                    + + + ++      p+++++g++D+++  
     EEA21705.1 410 QPQKENGI------PVIFMYGDHDWMDVT 432
                    22233333......999999999999864 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.4   0.0   2.5e-19   3.1e-16       3     116 ..     151     271 ..     149     301 .. 0.83
   2 ?    1.0   0.0      0.16   2.1e+02     179     204 ..     404     429 ..     393     449 .. 0.83

  Alignments for each domain:
  == domain 1  score: 59.4 bits;  conditional E-value: 2.5e-19
  Hydrolase_4   3 pkavvvlvHGlaehsgryaelaeaLa.aqGfavyalDhrGhGrse..gkrghvpsfddyvdDlaafvekvkeehpel....plfllGhSmGGlially 93 
                   ++ +v++HG++   g + + +e L  a+G++ yalD  G Grs   + + + ++ ++ ++ ++  +  + ee++ +    +++l+GhSmGG+ia++y
   EEA21705.1 151 TDQNLVMLHGYGAGLGFFYRNFEPLSrAKGWHLYALDLLGMGRSTrpPFKIKASDRQEAITEAENWFIDALEEWRIKrkieRFTLMGHSMGGYIAAAY 248
                  67889*************99999997357****************987777888888888888876644444554444666999************** PP

  Hydrolase_4  94 llrypdkvaglilsaPalkikak 116
                  +l+yp ++++lil++P+  ++ +
   EEA21705.1 249 ALKYPGRLNKLILVSPVGIPEDP 271
                  ****************9666554 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.16
  Hydrolase_4 179 amkrleeraakitlPllllhGeaDkv 204
                  a++++ + +++  +P+++++G++D+ 
   EEA21705.1 404 AAATASQPQKENGIPVIFMYGDHDWM 429
                  5667777788888***********85 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.5   6.6   2.7e-19   3.4e-16       1     218 [.     155     485 ..     155     487 .. 0.44

  Alignments for each domain:
  == domain 1  score: 60.5 bits;  conditional E-value: 2.7e-19
                    EEEE--GC.....GCHHHHHHHHCCT.CEEEEE--TTSTS-GGCS--HHHCHHH.HHHHCCTT...............TTSEEEEEETCHHHHHHH CS
  Abhydrolase_6   1 vlllHGagssassWlvapLaallaag.vhvlapDlpGhGrsdpppldledladl.aalldelaa.............gggpvvlvGHSlGGalala 81 
                    +++lHG g++ + + ++++ +l++a  +h +a+Dl G+Grs++pp+   +  d  +a ++e  +                ++ l+GHS+GG++a+a
     EEA21705.1 155 LVMLHGYGAGLGFF-YRNFEPLSRAKgWHLYALDLLGMGRSTRPPFKIKA-SDRqEA-ITEAENwfidaleewrikrKIERFTLMGHSMGGYIAAA 247
                    79***977664455.455544444444888***************99999.444133.222222244455559988888888************** PP

                    HHHCC.......EE.EEES-......................................----TTT....S----TTHHHHHHTT-CCCCHCCH... CS
  Abhydrolase_6  82 aapla.....lvvg.vlldp...........................pp.........talpagl....laaalelllallallrllawlsre... 128
                       +a     ++ + +l++p                           pp               +    +  +++++ ++++ l+  +w sr+   
     EEA21705.1 248 ---YAlkypgRLNKlILVSPvgipedpyavneamptdstegnangraPPrlprlvtylW-----DanvsPFSFIRWAGPFGPGLT-SRWTSRRfsh 334
                    ...888777955667*****888777777777765555555555554333333222220.....122222222222222222222.2444333333 PP

                    .S-HS..CCCCHHHC.........CCCHCHCCCGHH...............................HHCCHHCHTTCCHHTT-TTGC........ CS
  Abhydrolase_6 129 .plpr..lfladeda.........daawrarlarla...............................allaglgllpaaawadlpvpl........ 173
                     p+++   +++  ++         ++a ++ la++a                               +                            
     EEA21705.1 335 lPYAEasALHD-YTYsifrlrgsgEYALTYLLAPGAfarsplirriqgigrqvirpdspvaltsasdP-------------------Saaaatasq 410
                    31111111111.11011111222222222222222233333333333333333322222222221110...................011111112 PP

                    .........EEE.CTT-C......................HHHHCHHCCCH.STTEEETCE...SSS-HHHHSH.HHHH CS
  Abhydrolase_6 174 .........lvl.ggeDp......................lvprllerlla.qagarlpvvlpgaGHlphleep.deva 218
                             + + g+ D                          ++ e++ a   +a++  ++++aGH+++l e  +e++
     EEA21705.1 411 pqkengipvIFMyGDHDWmdvtggfaakekleeekrrilkD--ATPEQREAdNGSAKV-YIVKNAGHHLYL-EGdEEFN 485
                    22222222111212222233333332222222222222111..112222223355555.888888888888.6657766 PP

>> DUF915  Alpha/beta hydrolase of unknown function (DUF915)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   0.0   6.9e-09   8.9e-06      64     124 ..     193     252 ..     190     261 .. 0.93

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 6.9e-09
      DUF915  64 daknPiikvgfednrdaslkkqakwlkkvlseLkkkYnikkfnavGhSmGglaltsYleey 124
                 ++++P  k++  d ++  + + ++w+  +l+e + k +i++f ++GhSmGg  ++ Y+ +y
  EEA21705.1 193 RSTRPPFKIKASDRQE-AITEAENWFIDALEEWRIKRKIERFTLMGHSMGGYIAAAYALKY 252
                 57889999*****997.9****************************************998 PP

>> Esterase  Putative esterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.0   0.0   8.2e-08    0.0001     117     153 ..     233     269 ..     221     347 .. 0.73

  Alignments for each domain:
  == domain 1  score: 22.0 bits;  conditional E-value: 8.2e-08
                 EEEEEETHHHHHHHHHHHCSTTTCCEEEEES--S-CC CS
    Esterase 117 ravaGqSmGGlgALilalkhpdrFgsvssfSpivnps 153
                  +++G+SmGG++A  +alk+p+r    +  Sp+  p 
  EEA21705.1 233 FTLMGHSMGGYIAAAYALKYPGRLNKLILVSPVGIPE 269
                 579****************************885555 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0   2.6e-06    0.0034      61     109 ..     222     274 ..     203     316 .. 0.68
   2 ?   -3.2   0.0         5   6.4e+03     162     187 ..     412     437 ..     396     447 .. 0.59

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 2.6e-06
                    HTHHHHTETTCEEEEEEETHHHHHHHHHHHHHHHTT---EEEEEEESE.........- CS
  Abhydrolase_3  61 eqawelgadpsrivlaGdSaGGnlaaavalrardegepkvagqvliyP.........v 109
                    e+ w+++ + +r +l+G S GG +aaa al+   +    ++ ++l++P         v
     EEA21705.1 222 EE-WRIKRKIERFTLMGHSMGGYIAAAYALKYPGR----LNKLILVSPvgipedpyaV 274
                    22.78888899*******************99997....999******6654443322 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 5
                    -SST---EEEEEETT-TTHHHHHHHH CS
  Abhydrolase_3 162 dlsglpptlvvvaefDplrdegeaya 187
                    + ++  p++ + +++D++   g   a
     EEA21705.1 412 QKENGIPVIFMYGDHDWMDVTGGFAA 437
                    35556688889999999976654444 PP

>> Chlorophyllase2  Chlorophyllase enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   2.2e-06    0.0028      64     129 ..     208     267 ..     156     280 .. 0.88

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 2.2e-06
  Chlorophyllase2  64 ksaakvlnWlakgLesvlpeevepdlsklalsgHSrGgktafalalgkaktslkfsaligvdPvag 129
                      +++++  nW+ + Le   +  ++ ++++++l gHS Gg++a+a al++      ++ li v Pv  
       EEA21705.1 208 EAITEAENWFIDALE---EWRIKRKIERFTLMGHSMGGYIAAAYALKYPG---RLNKLILVSPVGI 267
                      556777899999999...6789999***********************99...8999999999975 PP

>> LIDHydrolase  Lipid-droplet associated hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0   4.9e-06    0.0063      13     120 ..     164     265 ..     155     269 .. 0.73

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 4.9e-06
  LIDHydrolase  13 GlveFYetFlsllseklnpelevlgishaGfeleeeekeakenekvfsLedQiehkedflkellek.aksekdvklilvGHSvGaYialevlkrlse 108
                   Gl  FY++F  l   k    +++++  + G+  +++      + k  + ++ i  +e+ + ++le+ + ++k  ++ l+GHS G Yia   + +++ 
    EEA21705.1 164 GLGFFYRNFEPLSRAK---GWHLYALDLLGMGRSTRP---PFKIKASDRQEAITEAENWFIDALEEwRIKRKIERFTLMGHSMGGYIAAAYALKYPG 254
                   5566777775544444...788888888888888777...22333344456666666655555565566889999**************99999999 PP

  LIDHydrolase 109 rsikkvvlLfPt 120
                   r  +k++l+ P+
    EEA21705.1 255 R-LNKLILVSPV 265
                   8.8888888875 PP

>> Abhydrolase_5  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0     2e-05     0.026      53      88 ..     227     263 ..     218     292 .. 0.79
   2 ?   -1.6   0.0       1.6     2e+03      96     131 ..     412     453 ..     393     464 .. 0.70

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2e-05
  Abhydrolase_5  53 apklekfvvgGhslGGvvasrfaaee.ekiegvvfla 88 
                    + k+e+f + Ghs+GG +a+ +a +  ++++ +++++
     EEA21705.1 227 KRKIERFTLMGHSMGGYIAAAYALKYpGRLNKLILVS 263
                    5689*******************98745888888765 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 1.6
  Abhydrolase_5  96 lselskkvlsivgteD......gvlnvkslekakkflpkdtk 131
                     +e++++v+ ++g++D      g +  ++le++k+++ kd++
     EEA21705.1 412 QKENGIPVIFMYGDHDwmdvtgGFAAKEKLEEEKRRILKDAT 453
                    356778888888888744444445677778888888877776 PP

>> Ndr  Ndr family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.0     1e-05     0.013      98     133 ..     230     265 ..     219     271 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 1e-05
                 ---EEEEEETHHHHHHHHHHHHSGGGEEEEEEES-- CS
         Ndr  98 lksviglGvgaGAyilarfalkhperveglvLinit 133
                 ++ +  +G   G yi a +alk+p r+  l+L+++ 
  EEA21705.1 230 IERFTLMGHSMGGYIAAAYALKYPGRLNKLILVSPV 265
                 566778***************************986 PP

>> Thioesterase  Thioesterase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.1   0.7     6e-05     0.077      66      87 ..     230     252 ..     153     263 .. 0.55

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 6e-05
                   S.SEEEEEETHHHHHHHHHHHHH CS
  Thioesterase  66 g.PyalfGhSlGgllAfevArqL 87 
                      ++l+GhS+Gg++A + A ++
    EEA21705.1 230 IeRFTLMGHSMGGYIAAAYALKY 252
                   247*************9988775 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0     9e-05      0.12      88     111 ..     228     250 ..     208     270 .. 0.74
   2 ?   -0.1   0.0      0.49   6.3e+02       3      27 ..     415     439 ..     413     464 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 9e-05
       PGAP1  88 keptsviliGHSmGGivaraaltl 111
                 +++++  l+GHSmGG +a a   l
  EEA21705.1 228 RKIERFTLMGHSMGGYIAAA-YAL 250
                 6778889**********944.333 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.49
       PGAP1   3 sGipVlFvpGnagsykqvrslAsea 27 
                 +GipV+F+ G    ++    +A++ 
  EEA21705.1 415 NGIPVIFMYGDHDWMDVTGGFAAKE 439
                 79********988887777777766 PP

>> Chlorophyllase  Chlorophyllase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   2.9e-05     0.037     100     156 ..     214     265 ..     154     276 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 2.9e-05
  Chlorophyllase 100 ieWlseglkavlptsveanlsklalvGhsrGGktafalalgysseltfsaliGvdPv 156
                      +W    l++     ++ ++++++l+Ghs GG  a a al+y    ++  li v Pv
      EEA21705.1 214 ENWFIDALEE---WRIKRKIERFTLMGHSMGGYIAAAYALKYPG--RLNKLILVSPV 265
                     4555555544...4688899**********************83..44556666665 PP

>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0     0.048        61       3      25 ..     141     163 ..     139     173 .. 0.85
   2 ?    7.7   0.0    0.0022       2.8      83     137 ..     210     263 ..     198     279 .. 0.74
   3 ?   -3.2   0.0       4.6   5.9e+03     148     171 ..     409     430 ..     402     451 .. 0.62

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.048
                    EEEEE--SS---EEEEEE--TT- CS
  Abhydrolase_2   3 iaevvspkdkaqavviflHGlGd 25 
                     ++v+  +++  + +++lHG+G+
     EEA21705.1 141 EFSVERIGEETDQNLVMLHGYGA 163
                    5678888899999*********7 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0022
                    HHHHHHHHHHHHHHHHHTT--GGGEEEEEETHHHHHHHHHHHT-SS--SEEEEES CS
  Abhydrolase_2  83 ikksaekleelidaelkkgipssriiigGFSqGaalalylaltlpkklggivafs 137
                    i ++ + + + ++++    ++ +r  ++G S+G+ +a + al++p +l   + +s
     EEA21705.1 210 ITEAENWFIDALEEW-RIKRKIERFTLMGHSMGGYIAAAYALKYPGRLNKLILVS 263
                    444444444444443.233788999**********************99888776 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 4.6
                    TTS-GGGGG-EEEEEEETT-SSS- CS
  Abhydrolase_2 148 ssatavtkklpilqiHgeeDpvvp 171
                    s++ + +  +p++ ++g+ D + +
     EEA21705.1 409 SQPQKEN-GIPVIFMYGDHDWM-D 430
                    4444445.57778888877753.4 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (504 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       479  (0.0267165); expected 358.6 (0.02)
Passed bias filter:                      387  (0.0215851); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.62u 0.28s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 3343.28
//
Query:       EEA21706.1  [L=381]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (381 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       956  (0.0533214); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 2581.61
//
Query:       EEA21707.1  [L=388]
Description: Cut9 interacting protein Scn1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.7e-33  116.1   0.0    3.6e-33  115.0   0.0    1.5  1  TatD_DNase  TatD related DNase


Domain annotation for each model (and alignments):
>> TatD_DNase  TatD related DNase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.0   0.0     2e-37   3.6e-33       1     252 [.      19     384 ..      19     386 .. 0.86

  Alignments for each domain:
  == domain 1  score: 115.0 bits;  conditional E-value: 2e-37
                 EEEEE-TTSCCCTTTHHHHHHHHHHTTEEEEEEE-SSGGGHHHHHHHHTT...........TTTEEEEE---GGGGGC..................... CS
  TatD_DNase   1 iDaHcHldskefeedreeileraeeagvaavvvvgtsskdskavlelakk..........ypnkvyavlGiHPnevde..................... 68 
                 +DaHcH+++          ++   + +v+a+ v++t+ +d++ v e+a++           ++k+++++G+HP+ +++                     
  EEA21707.1  19 FDAHCHPTD------TMVSISDIPHMNVTALTVMSTRGEDQELVDEVARRlgdyhceandGNGKIVPCFGWHPWFAHQirveedggdtttdteaiktrh 111
                 7********......5678999999***************999999999988877766555678*********************************** PP

                 ......................C.CCHH.HHHHHH.HHCCCTSEEEEEEEEEET......-CCCCCGH.............................HH CS
  TatD_DNase  69 ......................asedll.eelkel.anvkhskvvaiGeiGLDy......ysreestk.............................ea 108
                                       + ++ll   l e    +   +++++GeiGLD+             +                              +
  EEA21707.1 112 yrnvltgsvgnededisffktlPPPKLLsSLLVETkTRLIAHPNALVGEIGLDKafrlpmP------WhkdelgsrnesltpgsregrklspyrvtiAH 204
                 **********99999999988855555533334444555566777*********6666650......333344556677779999************** PP

                 HHHHHHHHHHHHHHTTEEEEEEEES-HHHHHHHH....................................HHCGGCCS.......EEEETT--S-HHHH CS
  TatD_DNase 109 qeevFeeqlrlAkelklplviHlrkaeedlleil....................................keaaeaka.......kvvlHsfsgsaeea 164
                 q++++++ql+lA e+++++++H+++a+  +le+                                     +      a       ++++Hs+sgs e +
  EEA21707.1 205 QKALLKAQLQLAGEMRRAVSVHSVQAHGVVLECFqelwkgherkvesnrrrkkrvnegrggeeeeeaeemE------AtplayppRICMHSYSGSPEAV 297
                 ********************************99999************************9987653221......23346889************** PP

                 HHHHHT....TEEEEE-GGGGTTT..THHHHHHHHHS-GGGEEE---TTSSEECCCTTSE--GGGHHHHHHHHHHHHTS-HHHHHHHHHHHHHH CS
  TatD_DNase 165 kkflkl....gyyislsglltfkn..akelrelvkavpldrlLiETDaPyltpkpyrgkrnepanvayvveklaelkaltleelaeitaeNakr 252
                 k++l      ++y+s+s +++f      +++++++++p+dr+LiE+D   l+       ++ +  ++ vv++++ +k+++le+  + +aeN  r
  EEA21707.1 298 KQLLRPsvpsDVYFSFSTVINFTGpsVDRVKSSLESLPDDRILIESD---LHV----AGKQMDDLLEDVVRTVCHVKGWSLEDGTKRLAENWGR 384
                 ****556899************9854556******************...344....367899********************99999999765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (388 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       504  (0.0281109); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.46
# Mc/sec: 2515.08
//
Query:       EEA21708.1  [L=561]
Description: hypothetical protein PMAA_055030 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.1e-20   72.3   0.0    4.7e-20   71.7   0.0    1.2  1  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.7   0.0   2.6e-24   4.7e-20       2     213 ..     109     314 ..     108     354 .. 0.87

  Alignments for each domain:
  == domain 1  score: 71.7 bits;  conditional E-value: 2.6e-24
  Fungal_trans   2 drffsnfhpqfpilhkpsflpkt......ssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslw 92 
                   ++ff  + p +p++ ++ f+ ++       +++++  +  + +l++++la+G +f++++ +  + +   +   +   +++ + l+  ++   +s + 
    EEA21708.1 109 SVFFNAVDPVYPLISRERFYIDYegfwelDDNQKPHVDTDFLALAFMVLAMGTQFLQTPGAPGQLQGAADF--YSSACYQSMRLY--SYLNRTS-VR 200
                   79***************************9******************************99866666643..444555555555..7888888.** PP

  Fungal_trans  93 ilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcdd 189
                    lq+ +++ +++++s++ +  + ++g+ vr a+  g +r+p   g     k  ++++ +rrRlw ++ + D + ++ lG pp   + ++ ++ P  d
    EEA21708.1 201 CLQAMVFMTYFLMNSGRASDGWAFSGTLVRQATAYGINREPTLFG----AKFNAFQILERRRLWHGIVCQDSFMSMSLGLPPVTMYGDVGVATPQRD 293
                   *********************************************....5699999999***********************999************ PP

  Fungal_trans 190 ddlwesddaseetlvetklsneek 213
                   d  ++s++ +e   +e+   ne +
    EEA21708.1 294 D-DDSSYSIAEAGGNEHA--NEDF 314
                   *.6666666665555543..3333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (561 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       439  (0.0244855); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.73u 0.34s 00:00:01.07 Elapsed: 00:00:00.57
# Mc/sec: 2970.53
//
Query:       EEA21709.1  [L=198]
Description: hypothetical protein PMAA_055040 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.5e-05   25.2   7.8    1.9e-05   24.9   7.8    1.2  1  YL1             YL1 nuclear protein
     0.0016   16.8   6.5     0.0016   16.8   6.5    1.1  1  CDC45           CDC45-like protein
  ------ inclusion threshold ------
       0.03   12.8   3.6      0.034   12.6   3.6    1.0  1  Rrn6            RNA polymerase I-specific transcription-initi
       0.19    9.9   6.6       0.19    9.9   6.6    1.1  1  Nop14           Nop14-like family
       0.19   11.7   3.8       0.31   11.1   3.8    1.4  1  RXT2_N          RXT2-like, N-terminal
       0.23    9.5   3.5       0.23    9.5   3.5    1.1  1  Sporozoite_P67  Sporozoite P67 surface antigen
       0.26   11.2   2.9       0.35   10.7   2.9    1.4  1  TLP-20          Nucleopolyhedrovirus telokin-like protein-20 
        9.2    4.2  13.2         11    3.9  13.2    1.1  1  DNA_pol_phi     DNA polymerase phi


Domain annotation for each model (and alignments):
>> YL1  YL1 nuclear protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.9   7.8   8.6e-09   1.9e-05      27      96 ..      99     163 ..      73     188 .. 0.81

  Alignments for each domain:
  == domain 1  score: 24.9 bits;  conditional E-value: 8.6e-09
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         YL1  27 lFaEeedDeefeseeeeeeeensDsdfdsdeedeesdeeedeeegekelerqerkkrkkekkkrkaqkkk 96 
                 +F+ e  D+e+ ++ee e e  s+ + d de+de++++e++e++    +e  er+k+   ++kr+++  +
  EEA21709.1  99 IFKREPLDDEWRCDEEAEGE--SEDENDNDEDDEQGNGEDEEDAPVDSIESDEREKK---RRKRNKPTLS 163
                 7889999******9988776..77799999999999999999999999999999999...5677665444 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   6.5   7.3e-07    0.0016     140     231 ..     103     196 ..      46     198 .] 0.62

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 7.3e-07
       CDC45 140 eeeddddeeeeeeeeedeedeeedeeeskkkrksksdeeeesddddersrkrrrsepsakklrrq.lkkerrkye.avlekyysqgtsygesvs 231
                 e  dd+   +ee e e+e+++++de++++ + ++++d+  +s ++der++krr++++ + + r+   kk+r +y+ ++ ++   +g+++g+s  
  EEA21709.1 103 EPLDDEWRCDEEAEGESEDENDNDEDDEQGNGEDEEDAPVDSIESDEREKKRRKRNKPTLSCRECvGKKMRVSYNaSKRDSSTMRGSFFGQSQG 196
                 4444443334444444444444444444344444455555577778888888888855555555575555555551556677889999999975 PP

>> Rrn6  RNA polymerase I-specific transcription-initiation factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   3.6   1.5e-05     0.034     691     804 ..      70     195 ..      20     197 .. 0.63

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.5e-05
        Rrn6 691 edpelsredplda.lsrytklikssptslsrs...vsniLshWelg.......sdpaeydwqrtesaleaeeq....rqrarrkrekrrrrkeklklas 774
                 ++ +l++   l + l+ y+ +++  ++s++++      + ++W  +       +d+++ d+++ + + e+ee+    +  + ++++krr+r++ +++ +
  EEA21709.1  70 ASVSLQQ---LKKpLAWYDQVHPIPYPSSPSNifkREPLDDEWRCDeeaegesEDENDNDEDDEQGNGEDEEDapvdSIESDEREKKRRKRNKPTLSCR 165
                 3333333...33344444444444444444333338888888987755666555566655555555555444489997778888899999999999999 PP

        Rrn6 775 raeasssssssqssssksssssssqlpsss 804
                 + +  +++ s ++s+++ss++++s + +s+
  EEA21709.1 166 ECVGKKMRVSYNASKRDSSTMRGSFFGQSQ 195
                 ***************999999999999888 PP

>> Nop14  Nop14-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   6.6   8.4e-05      0.19     359     413 ..     112     153 ..      43     189 .. 0.54

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 8.4e-05
       Nop14 359 ddlveseseeeeeeeeedeeeeedeeeeeeeeededdlsdleseeeeeedeleee 413
                 d++ e ese+e++++e+de+ + ++ee+                ++ e+de e++
  EEA21709.1 112 DEEAEGESEDENDNDEDDEQGNGEDEEDAPV-------------DSIESDEREKK 153
                 2222222222222222222222111111111.............11111111111 PP

>> RXT2_N  RXT2-like, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   3.8   0.00014      0.31      14      83 ..      72     144 ..      63     163 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00014
      RXT2_N  14 vhegrLnsskgdeelkkkveyngserkilsrnpierskrkkkekekeekeeeeedeegdeededdddee...e 83 
                 v+ ++L+++         + y  s  +i +r+p+  + r ++e e e+++e+++de++++ + +d++++   +
  EEA21709.1  72 VSLQQLKKPLAWYDQVHPIPYPSSPSNIFKREPLDDEWRCDEEAEGESEDENDNDEDDEQGNGEDEEDApvdS 144
                 5555565555554444678888888899998888886665566666555555555555555555544434430 PP

>> Sporozoite_P67  Sporozoite P67 surface antigen
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   3.5    0.0001      0.23      71     148 ..      85     164 ..      43     196 .. 0.61

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.0001
  Sporozoite_P67  71 ddsktvptpvseeiitrsfqepvsqeselqsdteineddkG.skedseedddeeeeedn..kstss.kdgkgskka.qpgvss 148
                     d+ + +p p s  +i +  +ep++ e + ++++e +++d+  ++ed+e+ +  e+eed   +s  s   +k+ +k  +p++s 
      EEA21709.1  85 DQVHPIPYPSSPSNIFK--REPLDDEWRCDEEAEGESEDENdNDEDDEQGN-GEDEEDApvDSIESdEREKKRRKRnKPTLSC 164
                     55666777777777765..57888888888888766554430333333333.3444443113333313334333333777554 PP

>> TLP-20  Nucleopolyhedrovirus telokin-like protein-20 (TLP20)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   2.9   0.00016      0.35     120     165 ..     115     159 ..      45     163 .. 0.63

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00016
      TLP-20 120 apveksssededdeddededeaakiesn...sdseesepssaKkqklDe 165
                 a +e+++++d+ dedde+++ +++   +   +ds es++  +K++k ++
  EEA21709.1 115 AEGESEDENDN-DEDDEQGNGEDE---EdapVDSIESDEREKKRRKRNK 159
                 22222222222.222223333333...2456899999999999999876 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9  13.2     0.005        11     642     680 ..     112     151 ..      94     185 .. 0.45

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.005
  DNA_pol_phi 642 dedeeddeeeeeeddeededse.eddde...eesdedeededd 680
                  de+ e ++e+e+++de+de+ + ed+++   +   + e+de++
   EEA21709.1 112 DEEAEGESEDENDNDEDDEQGNgEDEEDapvD---SIESDERE 151
                  22222222222222222222222222221111...11111111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (198 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1073  (0.0598472); expected 358.6 (0.02)
Passed bias filter:                      580  (0.0323498); expected 358.6 (0.02)
Passed Vit filter:                        83  (0.00462937); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.60u 0.30s 00:00:00.89 Elapsed: 00:00:00.50
# Mc/sec: 1184.86
//
Query:       EEA21710.1  [L=767]
Description: C6 transcription factor (AmdR), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.4e-19   68.3   0.1    1.2e-18   67.1   0.0    1.6  2  Fungal_trans  Fungal specific transcription factor domain
    4.7e-10   39.4  12.0    7.8e-10   38.7  12.0    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.1   0.0   1.4e-22   1.2e-18       2     190 ..     239     413 ..     238     437 .. 0.84
   2 ?   -2.8   0.1      0.28   2.5e+03      75     130 ..     503     564 ..     484     597 .. 0.69

  Alignments for each domain:
  == domain 1  score: 67.1 bits;  conditional E-value: 1.4e-22
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLl 98 
                   d +f++++p +p++ ++ f++++   n+ +s+  + lll ail  G + s++   ++  +l+++   +     r + l+  d + ++++   +q+ l
    EEA21710.1 239 DAYFKHINPGYPLVEEELFMSQY--RNRDPSNPPPVLLLQAILLCGVHVSRDSPERE--ELKNVL--Y----RRCKWLF--DNRIERNRDILVQTAL 323
                   78*********************..999999999999***************99998..344332..2....3777789..5555555456788999 PP

  Fungal_trans  99 llelyektssd..ralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrpp..llddsqinlpLPcddd 190
                   ll + +  ++d   a + +++gva r+a+ lg+hr+p +++        + ++ ++rR+ww     D++i+l +Grp   +l ds+++ + P d+ 
    EEA21710.1 324 LLTWHSDVLDDdvAANAHYWVGVAARIATGLGMHRDPISNK------FVATDRRTWRRVWWILVQYDVLISLSYGRPQaiNLEDSDVRPLTPADFV 413
                   9999999999745556666**********************......55555**************************866888888888888875 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.28
  Fungal_trans  75 raeilihedfsspssslwilqsLlllelyektssd..ralher.....hhgvavrlarslgLh 130
                   ra++++ ed+ + +  +++  + ++ +++e  +++  ++  +      ++  +++++++l+++
    EEA21710.1 503 RASAYS-EDYGPHDAEICSAAAGVITSIFEELRQKdcIKYLWCsgvhtLFTAMIQVRVELRFS 564
                   555555.88888888888888888888888888742455555577777777777777777776 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.7  12.0   8.7e-14   7.8e-10       2      39 ..      24      63 ..      23      64 .. 0.96

  Alignments for each domain:
  == domain 1  score: 38.7 bits;  conditional E-value: 8.7e-14
                S-HHHHHCT---ST...SSSS-HHHHHCT.HHHCCCCTCCCE CS
     Zn_clus  2 aCdnCrkkKvKCda...kkPaCsnCkkln.leCtfysesskr 39
                aC +C+++KvKCda   ++P CsnC++++ ++C+ ++e++kr
  EEA21710.1 24 ACVHCHRRKVKCDAqsvGFP-CSNCQSSGkTDCR-IHEKKKR 63
                9*******************.*************.9999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (767 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       528  (0.0294495); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.44
# Mc/sec: 5225.64
//
Query:       EEA21711.1  [L=408]
Description: aspergillopepsin A precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      6e-55  186.9   2.8    7.1e-55  186.6   2.8    1.0  1  Asp             Eukaryotic aspartyl protease
    4.5e-05   23.7   0.2    0.00093   19.5   0.1    2.8  3  TAXi_N          Xylanase inhibitor N-terminal
     0.0013   19.4   0.0        2.6    8.7   0.0    2.6  2  Asp_protease_2  Aspartyl protease


Domain annotation for each model (and alignments):
>> Asp  Eukaryotic aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  186.6   2.8   1.2e-58   7.1e-55       2     314 ..      94     399 ..      93     400 .. 0.89

  Alignments for each domain:
  == domain 1  score: 186.6 bits;  conditional E-value: 1.2e-58
                 EEEEEEETTTTEEEEEEEETT--SEEEEBTTESTSHCHHTSS-B-GGG-TT-EEEEEEEEEECTTS.EEEEEEEEEEEEETTEEEEEEEEEEEEEESSH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp   2 YfgeisiGtpeqkftvifDTGSsdlWVpsskckkssackshstydpskSstykkngkslsisYGdg.svsGflsqdtvkvggltvknqefgeatkepgs 99 
                 Y++++++G +   + +  DTGS d+W    ++       +h  y +  S+  k  ++ ++i+Y dg ++ G +++d+v+vg+++  nq++g a+  ++s
  EEA21711.1  94 YLSPVKVGNN--ILFLYPDTGSGDFWAYTRNTP---GAATH--YVYDTSTGTKLPNQYWHIEYIDGsTAGGAVYTDKVEVGNVSFSNQAIGIADYLQSS 185
                 8999999988..688899********9999987...45555..55557888999************9999************************99988 PP

                 HHTTSS.SSEEEE-S-GGGSCGG..SCCH.HHHHHHTTSSSSSEEEEEE-STTSSEEEEEESSEEGGGEEEEEEEEEESS.TSSTEEEEEEEEETTEEE CS
                 xxxxxx.xxxxxxxxxxxxxxxx..xxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxx RF
         Asp 100 tflaak.fdGiLGlgfkeisvee..atpv.fdnlvsqglikepvfsvylnreeeeggeivfGgvDeskykGsltyvpvts.kgywqielesvtvggktv 193
                 +++ ++ +dG++Gl+f+++++++   +p+ +dn++    +++pvf+ yl   ++++g   fG +D+sky+G+++y +v+s +g w+++l+++++g++ +
  EEA21711.1 186 QVVFTEiIDGMMGLAFSSLNTVRptKQPTfYDNVKP--SLQTPVFAAYLK--HNASGVFDFGFIDSSKYSGEIVYKDVDSsRGQWNVTLDGYSIGDTFS 280
                 87777659*************998744444888665..59*********5..999***********************997899***********9988 PP

                 EEEEEEEEEEETTCSSEEEEHHHHHHHHHHHTTEE.EETTCEEEEETTGGGGSEEEEEEETTEEEEEEGGGGEEEESSSTTSEEEESEEECCTSSSEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp 194 lcssgcqailDtGTsllalptsivekiakaigakk.sesegeyvvdCdslsslpdisftiggakitvpvselvlkeeeseesqCilglvseeegdlwiL 291
                   s+ ++ai+DtGTsll l+++iv+++   i +++ s  +g ++++C++  + p+++++ig  ++ +p++ l + +     ++C+ gl+ ++++++ iL
  EEA21711.1 281 -ASDCFNAIVDTGTSLLLLDHEIVQNYYAPIPSSQfSLRHGGWIFNCAD--DIPTFTVKIGPLDVVIPAEYLNYGSLG---TSCYGGLQCSPHNSYGIL 373
                 .99999*********************99997766255689*******7..*****************9999888774...58**************** PP

                 EHHHHTTEEEEEE...TTTTEEEEEE CS
                 xxxxxxxxxxxxx...xxxxxxxxxx RF
         Asp 292 GdvFlrsayvvfd...ldnnrvglAe 314
                 GdvFl+  yv+fd   +   rvg+A+
  EEA21711.1 374 GDVFLKVLYVIFDdgtTSSPRVGFAK 399
                 *************4444457999997 PP

>> TAXi_N  Xylanase inhibitor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0     0.092   5.5e+02       1      29 [.      94     120 ..      94     144 .. 0.74
   2 !   19.5   0.1   1.6e-07   0.00093      81     153 ..     145     214 ..     131     243 .. 0.73
   3 ?   -1.2   0.0      0.33     2e+03      14      29 ..     285     300 ..     280     318 .. 0.79

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.092
      TAXi_N   1 YlvsisiGtppqplklvvDtGsdltWvqC 29 
                 Yl  +++G++   l+l  DtGs  +W   
  EEA21711.1  94 YLSPVKVGNN--ILFLYPDTGSGDFWAYT 120
                 7788888887..8999********99876 PP

  == domain 2  score: 19.5 bits;  conditional E-value: 1.6e-07
      TAXi_N  81 yeisygadgssssGvlatdtltlsstdgksvkvpnlvfGCgk...snlgglaagadGilGLGrgklSlvsqlaskg 153
                  +i+y  dgs++ G + td++ +     ++v+++n ++G ++   s++  + +  dG++GL++++l  v  +++ +
  EEA21711.1 145 WHIEY-IDGSTAGGAVYTDKVEV-----GNVSFSNQAIGIADylqSSQVVFTEIIDGMMGLAFSSLNTVRPTKQPT 214
                 57999.5****************.....99**********99984444444456***********99998888665 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 0.33
      TAXi_N  14 lklvvDtGsdltWvqC 29 
                 ++++vDtG +l+ ++ 
  EEA21711.1 285 FNAIVDTGTSLLLLDH 300
                 7899*****9998775 PP

>> Asp_protease_2  Aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.1   0.0   0.00069       4.1      46      89 ..     149     200 ..     125     201 .. 0.67
   2 !    8.7   0.0   0.00044       2.6      10      39 ..     285     314 ..     268     356 .. 0.88

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00069
  Asp_protease_2  46 gaggevkarlvrldslklggltlknvpalvld........lgeeidglLGmd 89 
                      ++g++ +  v  d++++g++++ n+++ ++d          e idg++G+ 
      EEA21711.1 149 YIDGSTAGGAVYTDKVEVGNVSFSNQAIGIADylqssqvvFTEIIDGMMGLA 200
                     4567777777777888888888888888888865544443334557777765 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.00044
  Asp_protease_2  10 vrfllDTGasttlispelaeklglkvrese 39 
                     +++++DTG s +l++ e ++    +  +s+
      EEA21711.1 285 FNAIVDTGTSLLLLDHEIVQNYYAPIPSSQ 314
                     589***************999888777664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (408 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       367  (0.0204696); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2768.06
//
Query:       EEA21712.1  [L=219]
Description: CCAAT-binding factor complex subunit HapC [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.4e-29  101.4   1.2    3.2e-29  101.0   1.2    1.2  1  CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) a
    4.3e-06   27.1   0.0    7.1e-06   26.4   0.0    1.3  1  Histone        Core histone H2A/H2B/H3/H4
     0.0012   18.8   0.0     0.0017   18.3   0.0    1.2  1  TFIID-18kDa    Transcription initiation factor IID, 18kD subu
     0.0016   18.4   0.1     0.0025   17.8   0.1    1.3  1  Bromo_TP       Bromodomain associated
     0.0029   17.7   0.0     0.0039   17.3   0.0    1.2  1  CENP-T_C       Centromere kinetochore component CENP-T histon
  ------ inclusion threshold ------
      0.047   14.2   0.0      0.088   13.3   0.0    1.4  1  TFIID_20kDa    Transcription initiation factor TFIID subunit 


Domain annotation for each model (and alignments):
>> CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) and archaeal histone
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.0   1.2   1.1e-32   3.2e-29       2      65 .]      47     111 ..      46     111 .. 0.98

  Alignments for each domain:
  == domain 1  score: 101.0 bits;  conditional E-value: 1.1e-32
                    XXXHHHHHHHHHCC.TTXS-B-HHHHHHHHHHHHHHHHHHHHHHHHHHCCTTSSCE-HHHHHHHH CS
  CBFD_NFYB_HMF   2 eLPiarvkkImksd.pdarkiakdAkeliaecveefieelaseAaeickkekrKtikaehiklAv 65 
                    +LPia+v++Imk + p+++kiak+Ake+++ecv+efi++++seA+e+c++ekrKt+++e+i+ A+
     EEA21712.1  47 WLPIANVARIMKTAlPENAKIAKEAKECMQECVSEFISFITSEASEKCQQEKRKTVNGEDILFAM 111
                    8*************************************************************997 PP

>> Histone  Core histone H2A/H2B/H3/H4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.4   0.0   2.4e-09   7.1e-06      57     128 ..      43     111 ..       3     113 .. 0.84

  Alignments for each domain:
  == domain 1  score: 26.4 bits;  conditional E-value: 2.4e-09
                 XXSXXSXHHHHHHHHHHHH.TTSSSXEEXHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTXSEEXHHHHHHHH CS
     Histone  57 stdlliqklpfaRvvreivksekedlrisaeavlalqealEallvelfeeAnllakhaKRvTitpkDiqlAr 128
                 + d+  + + +aR+++   +   e+ +i +ea +++qe +  ++  +++eA+  + + KR+T++ +Di +A+
  EEA21712.1  43 EQDRWLPIANVARIMKTALP---ENAKIAKEAKECMQECVSEFISFITSEASEKCQQEKRKTVNGEDILFAM 111
                 55555566778888886665...7*********************************************998 PP

>> TFIID-18kDa  Transcription initiation factor IID, 18kD subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   5.7e-07    0.0017      20      64 ..      67     111 ..      53     134 .. 0.91

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 5.7e-07
                  --HHHHHHHHHHHHHHHHHHHHHHHC-XXXX...XXXXXXXXXXX CS
  TFIID-18kDa  20 PlqetvqlledlvrgyliellqqaakvaklrgsrkitlEDllfli 64 
                    +e+ +++++ v++++  ++ +a +  ++++++ ++ ED+lf++
   EEA21712.1  67 IAKEAKECMQECVSEFISFITSEASEKCQQEKRKTVNGEDILFAM 111
                  5678999************************************98 PP

>> Bromo_TP  Bromodomain associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.1   8.4e-07    0.0025      26      75 ..      69     118 ..      53     120 .. 0.92

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 8.4e-07
                 HHHHHHHHHHHHHHHHHHHHHHHHHHTTSS-SS--HHHHHHHHHHTT--G CS
    Bromo_TP  26 esaLEtLteiaqkYirelgeqaksfaehagRseptlkDvvltLqelginv 75 
                 ++a E ++e + ++i+ ++ +a++++  + R +++ +D+ +++  lg+++
  EEA21712.1  69 KEAKECMQECVSEFISFITSEASEKCQQEKRKTVNGEDILFAMTSLGFEN 118
                 6677999****************************************965 PP

>> CENP-T_C  Centromere kinetochore component CENP-T histone fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0   1.3e-06    0.0039       7      76 ..      47     113 ..      41     131 .. 0.86

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 1.3e-06
    CENP-T_C   7 slPaavvkklakrfakasgskaklekealkalekasdkffeqvgeDLeayakHagRKtidesDvilLmkr 76 
                  lP a v ++ k++     ++ak+ kea + ++++  +f++ ++++     +  +RKt++ +D++  m +
  EEA21712.1  47 WLPIANVARIMKTAL---PENAKIAKEAKECMQECVSEFISFITSEASEKCQQEKRKTVNGEDILFAMTS 113
                 478888877777764...469*******************************************998865 PP

>> TFIID_20kDa  Transcription initiation factor TFIID subunit A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0     3e-05     0.088      14      62 ..      63     111 ..      52     113 .. 0.91

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 3e-05
                  SS----HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-SEE-HHHHHHHH CS
  TFIID_20kDa  14 setkldedvedlLleiaddFvesvtkfacklakhRksdklevrDiqlhl 62 
                   ++k+ ++ ++ + e + +F++ +t+ a++  ++ k ++++  Di + +
   EEA21712.1  63 ENAKIAKEAKECMQECVSEFISFITSEASEKCQQEKRKTVNGEDILFAM 111
                  578999***************************************9975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (219 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       749  (0.0417759); expected 358.6 (0.02)
Passed bias filter:                      524  (0.0292264); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 1477.88
//
Query:       EEA21713.1  [L=118]
Description: prefoldin subunit 2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.7e-24   84.7   7.4    4.5e-24   84.4   7.4    1.1  1  Prefoldin_2  Prefoldin subunit
     0.0058   16.5   3.0       0.44   10.5   0.1    2.2  2  Prefoldin    Prefoldin subunit
  ------ inclusion threshold ------
      0.047   13.0   1.2          3    7.1   0.2    2.0  2  ATPase       KaiC
      0.078   13.4   3.0        6.4    7.2   0.8    2.1  2  DUF4376      Domain of unknown function (DUF4376)
      0.082   13.3   7.3        1.2    9.6   2.6    2.1  2  CC2-LZ       Leucine zipper of domain CC2 of NEMO, NF-kappa-B
      0.098   12.2   0.2       0.11   12.1   0.2    1.1  1  MCR_beta     Methyl-coenzyme M reductase beta subunit, C-term
       0.61    9.3   9.5        1.4    8.2   4.0    2.0  2  DUF3450      Protein of unknown function (DUF3450)


Domain annotation for each model (and alignments):
>> Prefoldin_2  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.4   7.4   1.8e-27   4.5e-24       1     106 []      13     118 .]      13     118 .] 0.98

  Alignments for each domain:
  == domain 1  score: 84.4 bits;  conditional E-value: 1.8e-27
                  HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS-TT--EEEEETTEEEEE-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Prefoldin_2   1 qelinkfqqlqqqlqqlaqqikqletqlkelelvleelelldedtkvyklvGdvlvkqdkeevkeeLeerketlekeiktlekqleklekeleelkee 98 
                  qel+ +++++++ lq +aq+i ++e++ +e++lv+e+le l  d+k+++lv +vlv++++ +v + L+++++ l+++++++ kq++ +++e++++k++
   EEA21713.1  13 QELQLQYSNYKNALQSMAQKIGDIEQETEEHKLVIETLEPLSADRKCFRLVNGVLVERTVGDVVPSLKTNADGLKQVLDEMVKQYKAKQTEMDNWKKK 110
                  899*********************************************************************************************** PP

                  HHCCTS-- CS
  Prefoldin_2  99 lqkklqqq 106
                  ++ ++ qq
   EEA21713.1 111 NNVQVVQQ 118
                  *9988775 PP

>> Prefoldin  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.0   0.2     0.002       5.2       1      34 [.      22      55 ..      22      64 .. 0.90
   2 !   10.5   0.1   0.00017      0.44      67     111 ..      64     108 ..      56     118 .] 0.88

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.002
                HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT CS
   Prefoldin  1 lkeeleslqaelaqlkeaieelektletlktlkk 34
                +k +l+s++++++ ++++ ee + ++etl+ l++
  EEA21713.1 22 YKNALQSMAQKIGDIEQETEEHKLVIETLEPLSA 55
                78999************************98887 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00017
                 TTEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Prefoldin  67 agyyveksleeAiellkkkleelekqlekleeeleklkdqittle 111
                  g+ ve+++ + +  lk + + l++ l+++ ++ + +++++++  
  EEA21713.1  64 NGVLVERTVGDVVPSLKTNADGLKQVLDEMVKQYKAKQTEMDNWK 108
                 79*************************************999765 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.2    0.0012         3      93     137 ..      14      57 ..       2      70 .. 0.76
   2 ?    5.4   0.1    0.0039       9.9      99     127 ..      78     106 ..      62     115 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0012
      ATPase  93 eesaee....kdkedleelieelaeaikeikakrvviDsitglayeeke 137
                 e    +    ++k++l+++++++ ++ +e++++++vi ++++l  +++ 
  EEA21713.1  14 EL---QlqysNYKNALQSMAQKIGDIEQETEEHKLVIETLEPL--SADR 57 
                 22...133468999****************************9..3333 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.0039
      ATPase  99 kdkedleelieelaeaikeikakrvviDs 127
                 + k++++ l++ l e++k++kak++ +D+
  EEA21713.1  78 SLKTNADGLKQVLDEMVKQYKAKQTEMDN 106
                 67889999****************99997 PP

>> DUF4376  Domain of unknown function (DUF4376)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   0.8    0.0025       6.4      55      97 ..      11      53 ..       1      56 [. 0.85
   2 ?    6.7   0.1    0.0035       9.1      25      59 ..      81     115 ..      61     117 .. 0.61

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0025
     DUF4376 55 dntvvtLtadqlialgqavaqhkqaifdrerelkaaieaaetl 97
                + + ++L+    ++  q +aq + +i ++++e+k  ie++e l
  EEA21713.1 11 KQQELQLQYSNYKNALQSMAQKIGDIEQETEEHKLVIETLEPL 53
                567778999999999***********************99965 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0035
     DUF4376  25 tdeesrar.lsgvllsaklageqgeeaWtladntvv 59 
                 t+++++++ l + ++++k+++++ ++ W+ ++n +v
  EEA21713.1  81 TNADGLKQvLDEMVKQYKAKQTEMDN-WKKKNNVQV 115
                 44444333145566666666666555.****99886 PP

>> CC2-LZ  Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   2.6   0.00046       1.2       9      62 ..       5      58 ..       1      62 [. 0.86
   2 ?    6.5   0.2    0.0041        11      13      44 ..      80     111 ..      73     116 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00046
      CC2-LZ  9 ekvkkeeieeLkaqlqaaeealaakqeeidelkeeikkkeeeletisvlkaQae 62
                ++++ ++ +eL+ q ++  +al+++ ++i ++++e ++++  +et++ l a   
  EEA21713.1  5 QQISVRKQQELQLQYSNYKNALQSMAQKIGDIEQETEEHKLVIETLEPLSADRK 58
                4566788899**********************************9999888655 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0041
      CC2-LZ  13 keeieeLkaqlqaaeealaakqeeidelkeei 44 
                 k + + Lk+ l++  ++++akq e+d+ k+++
  EEA21713.1  80 KTNADGLKQVLDEMVKQYKAKQTEMDNWKKKN 111
                 5677899*******************998876 PP

>> MCR_beta  Methyl-coenzyme M reductase beta subunit, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.2   4.2e-05      0.11      35     115 ..      30     107 ..       3     116 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 4.2e-05
    MCR_beta  35 vfemGdavGaferahllglayqGlnannlvydlvkengkegtvGtvveslveraiedkvikvekklpsgyklyetkdvalw 115
                 + ++Gd   + e ++l+  + + l a+   + lv+    e tvG+vv sl     +d++ +v +++  +yk  +t+ ++ w
  EEA21713.1  30 AQKIGDIEQETEEHKLVIETLEPLSADRKCFRLVNGVLVERTVGDVVPSLKTN--ADGLKQVLDEMVKQYKAKQTE-MDNW 107
                 3456777777888999999******************************9655..589989999998888776553.4444 PP

>> DUF3450  Protein of unknown function (DUF3450)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   4.0   0.00055       1.4      24      75 ..       4      55 ..       1      59 [. 0.86
   2 ?    4.7   0.2    0.0061        16      13      45 ..      78     110 ..      68     117 .. 0.80

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.00055
     DUF3450 24 eaekavaaaaqsqkkidklddekqellaeyralkeeleslevyneqlerlva 75
                +++ +v+++++ q +++++++  q++++++ ++++e+e+ ++  e le l a
  EEA21713.1  4 QQQISVRKQQELQLQYSNYKNALQSMAQKIGDIEQETEEHKLVIETLEPLSA 55
                67778999999**************************999999998887765 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.0061
     DUF3450  13 alaatldqalkeaekavaaaaqsqkkidkldde 45 
                 +l++++d ++++  + v++ ++ q+++d+++++
  EEA21713.1  78 SLKTNADGLKQVLDEMVKQYKAKQTEMDNWKKK 110
                 457788888888889999999999999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (118 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2153  (0.120085); expected 358.6 (0.02)
Passed bias filter:                      648  (0.0361426); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 793.86
//
Query:       EEA21714.1  [L=305]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.7e-15   55.3   0.1    1.2e-14   54.8   0.1    1.2  1  APH             Phosphotransferase enzyme family
  ------ inclusion threshold ------
      0.053   12.4   0.0       0.79    8.5   0.0    2.0  2  DUF1679         Protein of unknown function (DUF1679)
       0.12   11.9   0.0       0.17   11.5   0.0    1.3  1  Choline_kinase  Choline/ethanolamine kinase
       0.15   11.3   0.0       0.22   10.8   0.0    1.2  1  EcKinase        Ecdysteroid kinase
       0.46   10.7   5.9        2.2    8.6   0.3    2.3  2  DUF4611         Domain of unknown function (DUF4611)


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.8   0.1   3.4e-18   1.2e-14      74     202 ..       1     173 [.       1     199 [. 0.73

  Alignments for each domain:
  == domain 1  score: 54.8 bits;  conditional E-value: 3.4e-18
                 EE----EE-SS...HHHHHHHHHHHHHHHHHHCCHHCH...................................-STTTB-SHHCHTCCHHHHHHCHHH. CS
         APH  74 ieyvpgrsllr...klsaaqlpellealgeflaalhqv..................................dpaalpladflaqdlellrqlesata. 134
                 +e++pg+s++    +l+++q+ +l+++++e +a++ +                                   +++++   d+la++le  ++    ++ 
  EEA21714.1   1 MEFMPGASAYKrwrTLTMSQKVALVQRVAEIQAQIFRYsfygigtltiddeqqshpkeqpgemgnhfdydvaRGPFRSTYDWLASYLEIIIKDQTTAKe 99 
                 67888888888888*******************777774444444444444443333333333333333222455555559**9999999998888774 PP

                 CCCGCCTCCHHHHHHHHHHHHHHHH--S........SS-EEEE-SS-SGGGEEEC..TTEEEEE---TT-EEEECC CS
         APH 135 rllaselldlleeleeqvlaalaallpg........elptvllHgDlhpgNllvdpddgrvtGviDfedaglgppl 202
                    ++e + + ++++ +++ +la+llp+        +++ v++H D ++ N+l++ ++g++t ++D+e+++++pp 
  EEA21714.1 100 EAEDEEDE-EDAAFALALAHRLADLLPKifpslqnpPEQSVIWHEDMSLSNILIN-EQGEITPLLDWECVSAMPPW 173
                 44444444.478888889999**********************************.*****************774 PP

>> DUF1679  Protein of unknown function (DUF1679)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0     0.027        99     154     190 ..       1      37 [.       1      52 [. 0.93
   2 ?    8.5   0.0   0.00022      0.79     267     317 ..     137     185 ..     135     198 .. 0.80

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.027
     DUF1679 154 meyvedihtlsmyenikadelipvlkaiAtlqalsls 190
                 me++++    +  +++++++ +++++ +A++qa+ ++
  EEA21714.1   1 MEFMPGASAYKRWRTLTMSQKVALVQRVAEIQAQIFR 37 
                 8********************************9765 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00022
     DUF1679 267 kkvlvhgDlwsaNiLfseeeegklklkkviDyQlvslgnp..aeDlvrlllsc 317
                 + v+ h D+  +NiL +e++e    ++ ++D+  vs ++p  a+ + ++l ++
  EEA21714.1 137 QSVIWHEDMSLSNILINEQGE----ITPLLDWECVSAMPPwmATAVPKFLQGS 185
                 6799**************777....99**********9995555555666555 PP

>> Choline_kinase  Choline/ethanolamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   4.7e-05      0.17     103     177 ..      96     170 ..      18     178 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 4.7e-05
                     CCS.TT..ECHHGGCCHCCCTHHHHHHHHHTHHHHHHCHGG-EEEE-S--SGGGEEE.-CTTEEEE--GTT-EEE CS
  Choline_kinase 103 nkeaqtkakkekkkkqlklinledlekelekleklleelespvvfcHnDlqegNillnkeekklvlIDFEYagyn 177
                       +++ ++++++++  + l   ++l + l k+   l++  ++ v  H D+  +Nil n++ +   l D+E  +++
      EEA21714.1  96 TAKEEAEDEEDEEDAAFALALAHRLADLLPKIFPSLQNPPEQSVIWHEDMSLSNILINEQGEITPLLDWECVSAM 170
                     2333344444455555566666677777777777777788889**************7666666799***76665 PP

>> EcKinase  Ecdysteroid kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   6.2e-05      0.22     144     245 ..      66     164 ..      55     190 .. 0.69

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 6.2e-05
    EcKinase 144 elkkglleedyvssalkeafeelleellkaalealreelpelekeaekle.klkenlferllelve..ekeeefnvlnHGDlwvnNimfkydeegeped 239
                 ++++++   +++s+   ++++++le  +k   +a +e+ +e ++e++++  +l+ +l + l +++   +++ e +v+ H D+ ++Ni+++ + e     
  EEA21714.1  66 HFDYDVARGPFRSTY--DWLASYLEIIIKDQTTAKEEAEDEEDEEDAAFAlALAHRLADLLPKIFPslQNPPEQSVIWHEDMSLSNILINEQGE----I 158
                 555555555666664..78888888888887777766666666565444315555666666666668999******************965433....3 PP

    EcKinase 240 vilvDF 245
                 + l+D+
  EEA21714.1 159 TPLLDW 164
                 455666 PP

>> DUF4611  Domain of unknown function (DUF4611)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.9     0.013        46      58      74 ..      94     110 ..      87     115 .. 0.63
   2 ?    8.6   0.3   0.00061       2.2      38      79 ..     174     221 ..     167     224 .. 0.72

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.013
     DUF4611  58 vaaagdeeeegededde 74 
                 +++a++e+e++ede+d+
  EEA21714.1  94 QTTAKEEAEDEEDEEDA 110
                 45555555555665554 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.00061
     DUF4611  38 lreevsellstlveqe......aqddvaaagdeeeegededdeeeekn 79 
                 + + v+++l+  v++e       +d+++++++   +ged+d ++e kn
  EEA21714.1 174 MATAVPKFLQGSVREEepkrqdYADETENEPETPVDGEDDDLDNEGKN 221
                 778899999998887778744455666666667777888876666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (305 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       665  (0.0370907); expected 358.6 (0.02)
Passed bias filter:                      508  (0.028334); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 2030.63
//
Query:       EEA21715.1  [L=924]
Description: mRNA splicing factor RNA helicase (Prp16), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.9e-21   75.4   1.8    1.3e-20   73.6   0.0    2.7  3  HA2          Helicase associated domain (HA2)
    3.4e-17   62.6   0.0    9.5e-17   61.1   0.0    1.8  1  OB_NTP_bind  Oligonucleotide/oligosaccharide-binding (OB)-fol
    1.8e-15   57.2   0.0    4.2e-15   56.0   0.0    1.6  1  Helicase_C   Helicase conserved C-terminal domain
    2.2e-06   27.6   0.0      5e-06   26.4   0.0    1.6  1  DEAD         DEAD/DEAH box helicase
     0.0001   22.6   0.1    0.00031   21.0   0.1    1.8  1  AAA_22       AAA domain
     0.0019   17.3   0.0     0.0041   16.2   0.0    1.5  1  T2SSE        Type II/IV secretion system protein
     0.0019   17.9   0.3     0.0057   16.3   0.3    1.8  1  SRP54        SRP54-type protein, GTPase domain
     0.0022   17.7   0.0     0.0052   16.5   0.0    1.6  1  AAA_30       AAA domain
     0.0025   17.2   0.0     0.0048   16.3   0.0    1.4  1  ATPase       KaiC
     0.0033   16.7   0.0      0.006   15.9   0.0    1.4  1  DUF2075      Uncharacterized conserved protein (DUF2075)
     0.0061   16.9   0.2      0.028   14.8   0.0    2.1  2  AAA_19       AAA domain
  ------ inclusion threshold ------
       0.02   14.9   0.0        8.8    6.3   0.0    2.5  2  ResIII       Type III restriction enzyme, res subunit
      0.026   14.5   0.0      0.047   13.7   0.0    1.4  1  Flavi_DEAD   Flavivirus DEAD domain
      0.046   13.6   1.6       0.31   11.0   0.7    2.6  2  NACHT        NACHT domain
      0.048   13.7   0.2       0.25   11.4   0.2    2.1  1  AAA_14       AAA domain
      0.075   13.2   0.4        0.6   10.3   0.0    2.6  2  AAA_33       AAA domain
       0.11   13.0   0.1       0.34   11.4   0.0    1.9  1  ABC_tran     ABC transporter
       0.15   11.8   0.0       0.28   10.9   0.0    1.4  1  AAA_24       AAA domain
       0.15   12.4   0.0        0.4   11.0   0.0    1.7  1  AAA_16       AAA ATPase domain


Domain annotation for each model (and alignments):
>> HA2  Helicase associated domain (HA2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       2.6   2.4e+03      79      93 ..     110     124 ..      73     144 .. 0.53
   2 !   73.6   0.0   1.4e-23   1.3e-20       4     108 .]     582     668 ..     579     708 .. 0.83
   3 ?   -2.4   0.9       6.3     6e+03      81      94 ..     836     849 ..     804     863 .. 0.44

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 2.6
         HA2  79 eekakkkrkeeekar 93 
                 e++++++r+++++++
  EEA21715.1 110 ERRQQRERQKQAQEA 124
                 222333333333322 PP

  == domain 2  score: 73.6 bits;  conditional E-value: 1.4e-23
         HA2   4 lLvalgALdeegnlTelGrkmaelPlsprlakmLlaaaeleegcldevitivAalsveeifleeneeekeeeeeeeekakkkrkeeekarrklahkdae 102
                  L +lgALd+ g+lT+lGr+m  +P++p+lak+L++a+e e gc +ev+tiv++lsv ++f +++e ++e+++               ar+k+  ++  
  EEA21715.1 582 ELWSLGALDNLGDLTPLGRRMTPFPMDPSLAKLLITASE-EYGCSEEVLTIVSMLSVPNVFFRPKERQEESDA---------------AREKFFVPE-- 662
                 699******99**************************65.59**********************976544433...............222233333.. PP

         HA2 103 gDhltl 108
                 +Dhltl
  EEA21715.1 663 SDHLTL 668
                 666664 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 6.3
         HA2  81 kakkkrkeeekarr 94 
                 +a+++r+++ek+r+
  EEA21715.1 836 AADRERAAAEKERE 849
                 11222222222111 PP

>> OB_NTP_bind  Oligonucleotide/oligosaccharide-binding (OB)-fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.1   0.0     1e-19   9.5e-17       1      81 [.     726     803 ..     726     805 .. 0.94

  Alignments for each domain:
  == domain 1  score: 61.1 bits;  conditional E-value: 1e-19
                  HHHHHHHHHTTCEEEEEETTCCEEETTTCEEEEE-TTSTTTTT...TSSSEEEEEEEEESSSEEEEEEEEE-HHHHHHHST CS
  OB_NTP_bind   1 lraillaGlypqiarkdpskkdyktartktrvfihpsSvlaknekekepewvvytelvettklylrdltaidpawLllfag 81 
                  +r+++++G+y q ark+  ++ +  +rt+  v++hp+S+l        p++vvy+el+ t+k y+ ++ta+dp wL++++g
   EEA21715.1 726 IRKCICSGYYHQAARKKGLGE-FINLRTSVTVQLHPTSALYG--LGYVPDYVVYHELILTSKEYMSTVTAVDPHWLAELGG 803
                  89************8888887.999*9**************7..569*******************************997 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.0   0.0   4.5e-18   4.2e-15       8     111 .]     389     517 ..     381     517 .. 0.84

  Alignments for each domain:
  == domain 1  score: 56.0 bits;  conditional E-value: 4.5e-18
                 HHHHHTTTTSEEEEEESSHHHHHH........HHHHHHHT...TSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSS. CS
  Helicase_C   8 ellkleeeggkilifvntidrlek........vklllekk...gikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlp. 94 
                 ++ + ++  g+il+f++ ++++e         +kll   +   +++++++++++p++++ +i+e+   g ++v++at++ae++++++++ +V++ ++  
  EEA21715.1 389 AI-HVSQGPGDILVFMTGQEDIEAtcdlveerLKLL---NdppKLSILPIYSQMPAEQQAKIFEKAAPGVRKVIVATNIAETSLTVDGIMYVVDSGFSk 483
                 44.4678899**********7766634454444555...1466*******************************************************7 PP

                 ...SSH..............HHHHHHHTTSSSTT CS
  Helicase_C  95 ...rnv..............tsyiqriGRtgRag 111
                    +n+              +++ qr+GR+gR g
  EEA21715.1 484 lkvYNPrmgmdtlqitpisqANAGQRAGRAGRTG 517
                 66644488999999999999************86 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.4   0.0   5.3e-09     5e-06       7     171 ..     197     346 ..     182     351 .. 0.74

  Alignments for each domain:
  == domain 1  score: 26.4 bits;  conditional E-value: 5.3e-09
                 HHHHHHTTCEEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTCSEEEEEH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   7 aiplilgggdvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngvdivvgtp 105
                  +  i +++ ++v +eTGsGKT+     +++  y   gk+g ++ +  P r  a  +++++++ ++ +dl  l  + g a r +  +   ++ i ++t 
  EEA21715.1 197 LLRVIRDNQVIIVVGETGSGKTTQLTQFLYEDGY---GKQG-MIGCTQPRRVAAMSVAKRVSEEMS-VDLGDL--V-GYAIRFEDCTS-DKTVIKYMTD 286
                 455666788899**********996666655554...4555.78899******************9.453333..3.34444444444.5588999*** PP

                 HHHHH.HHHCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBS.H CS
                 xxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.x RF
        DEAD 106 grldd.llstgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlp.k 171
                 g l++  l +   +l++ +++++DEa++   +   d +  +++++     d k    +iv SAT++ +
  EEA21715.1 287 GVLLReSLVQP--DLDKYSCIIMDEAHERALN--TDVLMGLIKKVLVRRRDLK----LIVTSATMNsE 346
                 **999433334..4*************98887..7777777777744444444....********944 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0   0.1   3.3e-07   0.00031       4     127 ..     203     338 ..     200     347 .. 0.62

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 3.3e-07
      AAA_22   4 tagilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelka...................erlsseell.eal 82 
                 + ++++v+Ge+G+GKTt l ++l+++         + + + +t p      ++++++ +++ ++l +                   +  +   l+ +++
  EEA21715.1 203 DNQVIIVVGETGSGKTTQLTQFLYEDGYG------KQGMIGCTQPRRVAAMSVAKRVSEEMSVDLGDlvgyairfedctsdktvikYMTDGVLLReSLV 295
                 6789*********************8533......4444444444444555555555555555555555555555544455555555555555555555 PP

      AAA_22  83 eqalraravielliiDEaqh..lrseealeeL..rsllnlsrkgvqliL 127
                 +  l++++   ++i DEa+   l + ++l  L  + l+   r +++li+
  EEA21715.1 296 QPDLDKYS---CIIMDEAHEraL-NTDVLMGLikKVLVR--RRDLKLIV 338
                 55555554...59*****98544.444444443555666..77777775 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   4.3e-06    0.0041     114     150 ..     193     225 ..     159     237 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 4.3e-06
       T2SSE 114 lkekiaevlrkavrerglilvsGgTgsGKttllyall 150
                 ++e++ +v+    r +++i+v G TgsGKtt l   l
  EEA21715.1 193 VREDLLRVI----RDNQVIIVVGETGSGKTTQLTQFL 225
                 445555555....55599*************997765 PP

>> SRP54  SRP54-type protein, GTPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.3   6.1e-06    0.0057       2     128 ..     205     346 ..     204     352 .. 0.69

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 6.1e-06
                 EEEEEEESTTSSHHHHHHHHHHHHHHTTS-EEEEEESTSSTTHHHHHHHHHHHTTEEEEE..........SSTTSCHHHHHHHHH......HHHHHTTS CS
       SRP54   2 nvillvGlqGaGKTttlaKLaallkkegkkvllvaaDtfRaaAveQLktlaeklgvpvik..........kkeeadpaavakeav......ekakeeki 84 
                 +vi++vG +G+GKTt l++   +    gk+ ++ ++   R+aA+   k + e++ v++ +           ++++  ++++ ++v       + + +k+
  EEA21715.1 205 QVIIVVGETGSGKTTQLTQFL-YEDGYGKQGMIGCTQPRRVAAMSVAKRVSEEMSVDLGDlvgyairfedCTSDKTVIKYMTDGVllreslVQPDLDKY 302
                 69*************999875.444459*************************9998765555666654423333444444444311110044455667 PP

                 SEEEEEE--SSTTHHHHHHHHHHHHHHHSSSEEEEEEETTBHTH CS
       SRP54  85 dvvlvDTaGrlqndkelmeelkkikkvvkpdevllvldattgqe 128
                  ++++D a   + +++++  l k   v + d +l+v +at+ +e
  EEA21715.1 303 SCIIMDEAHERALNTDVLMGLIKKVLVRRRDLKLIVTSATMNSE 346
                 77888887777777777777777777777777777777777766 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   5.5e-06    0.0052      16      98 ..     203     311 ..     194     338 .. 0.71

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 5.5e-06
      AAA_30  16 sgdrvavltGpAGtGKttalkal..reaweaag.......grviglAptgkaAkvLaeelg......i...eastiakllkrlk............... 81 
                 + ++v +++G  G+GKtt l++   ++ + ++g       +rv++++  ++++++++ +lg      i   ++ + +      +               
  EEA21715.1 203 D-NQVIIVVGETGSGKTTQLTQFlyEDGYGKQGmigctqpRRVAAMSVAKRVSEEMSVDLGdlvgyaIrfeDCTSDK------Tvikymtdgvllresl 294
                 4.469***************99766888888889***********************77774433331333222222......1222224566777777 PP

      AAA_30  82 grarlepgtllivDEag 98 
                  + +l++ +++i DEa 
  EEA21715.1 295 VQPDLDKYSCIIMDEAH 311
                 66789999999999995 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   5.1e-06    0.0048      16      77 ..     201     264 ..     195     292 .. 0.72

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 5.1e-06
      ATPase  16 ipegrvvlitGepGtGKtifalqFlikgaekygepgvfvtveepa...edlrenak.slGwdlekl 77 
                 i +++v+ ++Ge+G+GKt+   qFl++    yg++g++  +  +    +++ ++++ ++ +dl +l
  EEA21715.1 201 IRDNQVIIVVGETGSGKTTQLTQFLYED--GYGKQGMIGCTQPRRvaaMSVAKRVSeEMSVDLGDL 264
                 67899*********************98..678888765444443444444444433566666555 PP

>> DUF2075  Uncharacterized conserved protein (DUF2075)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   6.4e-06     0.006       2      98 ..     205     311 ..     204     330 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 6.4e-06
     DUF2075   2 avvlVtGvaGtGKtvvllnllael.......eddeeertavylsvNhplvlvlrealakkeekkkkkeafeklssfinnlsef...kkaeekkeepked 90 
                 +v++V G++G+GKt  l ++l+e            + r+++ +sv ++  + +  +l        + e+ +  +++i+ ++ +   ++   + + +k  
  EEA21715.1 205 QVIIVVGETGSGKTTQLTQFLYEDgygkqgmIGCTQPRRVAAMSVAKRVSEEMSVDLGDLVGYAIRFEDCTSDKTVIKYMTDGvllRESLVQPDLDKYS 303
                 79**********************8887776666699999999999999999999997666666777889999999999999999999999999***** PP

     DUF2075  91 vvivDEAh 98 
                 ++i+DEAh
  EEA21715.1 304 CIIMDEAH 311
                 ******** PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0       3.7   3.5e+03      47      78 ..      97     143 ..      81     184 .. 0.63
   2 !   14.8   0.0   2.9e-05     0.028       9     129 ..     203     331 ..     196     338 .. 0.67

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 3.7
      AAA_19  47 lvaftgrAakelrerlaalgae.....atTiHrlal..........l 78 
                 ++ f ++  k +rer ++ +++     atT+ + al           
  EEA21715.1  97 MAVFSRKGSKVVRERRQQRERQkqaqeATTMAGTALgnligikedeG 143
                 56677888888888774444436666699999887766666443330 PP

  == domain 2  score: 14.8 bits;  conditional E-value: 2.9e-05
      AAA_19   9 kekvllvtaGpGtGKTrvlkhivallvelgg.....vkpeeillvaftgrAakelrerlaalgaeatTiHrlalldfddlltealelleeaeeekklqe 102
                  ++v++v++  G+GKT+ l++ + +    ++      +p++++++++++r  +e++  l  l + a  +   +  ++  + ++   ll+e+  + +l +
  EEA21715.1 203 DNQVIIVVGETGSGKTTQLTQFLYEDGYGKQgmigcTQPRRVAAMSVAKRVSEEMSVDLGDLVGYAIRFEDCTSDKTVIKYMTDGVLLRESLVQPDL-D 300
                 6899***************999865433332111115669999999999999999999988888877777763322222222223355576777888.6 PP

      AAA_19 103 ee.llivDEfqd..vd.elqyrLlkallgek 129
                 ++ ++i DE+ +  ++ ++ + L+k++l ++
  EEA21715.1 301 KYsCIIMDEAHEraLNtDVLMGLIKKVLVRR 331
                 666******9763355566677777776555 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   0.0    0.0093       8.8      21      45 ..     190     225 ..     114     228 .. 0.77
   2 ?    5.9   0.0     0.012        11     127     146 ..     296     315 ..     273     345 .. 0.71

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0093
                 .............TTSEEEEEESTTSTHHHHHHHHH CS
      ResIII  21 s...........krdkrglikmaTGtGKTlvaakli 45 
                 +           ++++ ++++ +TG+GKT  ++++ 
  EEA21715.1 190 AfavredllrviRDNQVIIVVGETGSGKTTQLTQFL 225
                 044444455555777788899********9877765 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.012
                 HHHTTT-SEEEEETGGGTTS CS
      ResIII 127 ellrdrfdviiiDEaHrlga 146
                 + + d++ +ii+DEaH  + 
  EEA21715.1 296 QPDLDKYSCIIMDEAHERAL 315
                 56778999********8665 PP

>> Flavi_DEAD  Flavivirus DEAD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   4.9e-05     0.047       3     135 ..     203     342 ..     201     347 .. 0.68

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 4.9e-05
                 X--EEEEE--TTS-TTTTHHHHHHHHHHHTT--EEEEESSHHHHHHHHHHTT.TS-EEE--...--..---------SEEEEEHHHHHHHHHHT----- CS
  Flavi_DEAD   3 kkkltvldlhPGaGktrkvlpelvkeaierrlrtlvLaPtrvvlaemeealk.glevrykt...sa..vkeektgrelvdvmchatftkrllspvrkkn 95 
                 ++++ ++    G+Gkt ++   l ++ + ++       P rv +  +++ ++ +++v        a  +++ ++++ ++  m    + +  l +    +
  EEA21715.1 203 DNQVIIVVGETGSGKTTQLTQFLYEDGYGKQGMIGCTQPRRVAAMSVAKRVSeEMSVDLGDlvgYAirFEDCTSDKTVIKYMTDGVLLRESLVQPDLDK 301
                 56677777788999999888888888888887777778888876666555431344443221112211346677899********************** PP

                 -SEEEEETTT--SHHHHHHHHHHHH.HHHTTS-EEEEEESS CS
  Flavi_DEAD  96 yeliimDeahflDPasiaarGylet.kaeegeaalilltat 135
                 y  iimDeah    +     G +++ ++++++ +li  +at
  EEA21715.1 302 YSCIIMDEAHERALNTDVLMGLIKKvLVRRRDLKLIVTSAT 342
                 **********7666655556665542345555566665555 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.7   0.00032      0.31       2     130 ..     206     341 ..     205     355 .. 0.56
   2 ?   -2.3   0.0       3.8   3.6e+03      22      58 ..     673     709 ..     668     726 .. 0.58

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00032
                 CEEEEC-TTTCHHHHHHHHHHHHCTS-SC..CCC.-SEEEEEETTTTTTS-.......-HCHHHCCCCTS--SSS-CCHHHHCCSCCCEE......... CS
       NACHT   2 lvilqGeaGsGKTtLlqklalawaegklp..qga.fklvFflslrelsrsgna....rsladllfsqlpepaapvsevwavllelperlL......... 84 
                 ++i+ Ge GsGKTt l ++  +   gk+   +++  + v  +s++++  ++ +      + + ++ + + + ++v ++++  + l+e+l+         
  EEA21715.1 206 VIIVVGETGSGKTTQLTQFLYEDGYGKQGmiGCTqPRRVAAMSVAKRVSEEMSvdlgDLVGYAIRFEDCTSDKTVIKYMTDGVLLRESLVqpdldkysc 304
                 79*************999987654444320022223333333333333333333433334444455555555555555555555555555666666666 PP

                 EEEE-STT-SS-TCH.........HHHHHCTTTTT--EEEEEEECC CS
       NACHT  85 lilDglDelvtdlgqkekqpvrtlLselirkkllpeasllltvrpr 130
                 +i+D + e +            ++L +li+k l+++  l+l+v++ 
  EEA21715.1 305 IIMDEAHERALNT---------DVLMGLIKKVLVRRRDLKLIVTSA 341
                 6666665555422.........346677777777777666666665 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 3.8
                 HHHCTS-SCCCC-SEEEEEETTTTTTS-....-HCHHH CS
       NACHT  22 lawaegklpqgafklvFflslrelsrsgna.rsladll 58 
                 ++w+++ +   a ++  fl++++l+r +++   l d++
  EEA21715.1 673 TQWKSNGYSD-AWCVRHFLHSKSLRRAKEIrEQLHDIM 709
                 5555555433.456666666666666665543444443 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.2   0.00027      0.25       2      99 ..     204     340 ..     203     354 .. 0.68

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00027
      AAA_14   2 rkilvitGaRrvGKTtllkqlikell.........vkkesilyinldderd.................kkladpe.....kllelileklke....... 62 
                 +++++++G   +GKTt l q+++e           ++++++  +++ +                    +     +     ++++++ +   +       
  EEA21715.1 204 NQVIIVVGETGSGKTTQLTQFLYEDGygkqgmigcTQPRRVAAMSVAKRVSeemsvdlgdlvgyairfE-----DctsdkTVIKYMTD---Gvllresl 294
                 789******************999888999999998888888888877655445555555555443321.....13222333333333...03334567 PP

      AAA_14  63 .....ekktylflDEiqevpewekalkslvd....egknldvivtG 99 
                      +k +++++DE++e     ++l +l++    ++++l++ivt 
  EEA21715.1 295 vqpdlDKYSCIIMDEAHERALNTDVLMGLIKkvlvRRRDLKLIVTS 340
                 7778888889999999998666666555555333366788888885 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.3       1.7   1.6e+03     109     129 ..     106     125 ..      93     131 .. 0.70
   2 ?   10.3   0.0   0.00063       0.6       1      46 [.     206     256 ..     206     375 .. 0.70

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 1.7
      AAA_33 109 etlkeRlakRaangddrsevp 129
                 ++ +eR ++R+++++++ e++
  EEA21715.1 106 KVVRERRQQRERQKQAQ-EAT 125
                 67899999999986544.333 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00063
      AAA_33   1 lvllvGlpGsGKstlaerllkklg.....avllssdtlrrrlfgtdqqskt 46 
                 ++++vG  GsGK+t +++ l + g     ++  +++    ++ + ++ s++
  EEA21715.1 206 VIIVVGETGSGKTTQLTQFLYEDGygkqgMIGCTQPRRVAAMSVAKRVSEE 256
                 89*************999977766555557777777766666655555444 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00036      0.34       9      42 ..     202     236 ..     197     310 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00036
                 ETTSEEEEEESTTSSHHH.HHHHHTTSS--SEEEE CS
                 xxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx RF
    ABC_tran   9 kegekvaivGenGaGKSt.LlkllagllkpteGei 42 
                 + ++++ +vGe+G+GK+t L + l++    ++G i
  EEA21715.1 202 RDNQVIIVVGETGSGKTTqLTQFLYEDGYGKQGMI 236
                 678999***********944455565555566666 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00029      0.28       2      72 ..     204     308 ..     203     313 .. 0.58

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00029
      AAA_24   2 klkiliyGpsgiGKTtlakel.......gpkplfi.....................dtekGlksldadkfpdieswedfldevvel........aaela 64 
                 ++ i+++G+ g+GKTt+++++       +    +i                      ++ G    +a++f+d++s ++++++++          + +l+
  EEA21715.1 204 NQVIIVVGETGSGKTTQLTQFlyedgygK--QGMIgctqprrvaamsvakrvseemSVDLGDLVGYAIRFEDCTSDKTVIKYMTDGvllreslvQPDLD 300
                 6789****************977666441..22222244444444455666655555555666666666666654444444444434445555555556 PP

      AAA_24  65 dyktlviD 72 
                 +y+ ++ D
  EEA21715.1 301 KYSCIIMD 308
                 66666655 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00042       0.4      15      45 ..     197     225 ..     192     243 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00042
      AAA_16  15 alervrsgrpelvllsGesGvGKsslvrell 45 
                 +l+ +r++  ++++++Ge G+GK++ ++++l
  EEA21715.1 197 LLRVIRDN--QVIIVVGETGSGKTTQLTQFL 225
                 55555555..689************999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (924 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       812  (0.0452898); expected 358.6 (0.02)
Passed bias filter:                      585  (0.0326287); expected 358.6 (0.02)
Passed Vit filter:                        96  (0.00535445); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              19  [number of targets reported over threshold]
# CPU time: 0.83u 0.33s 00:00:01.15 Elapsed: 00:00:00.47
# Mc/sec: 5896.98
//
Query:       EEA21716.1  [L=173]
Description: oligosaccharyl transferase subunit Dad1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.8e-46  155.3   4.1    2.2e-45  153.5   4.1    1.8  1  DAD       DAD family
  ------ inclusion threshold ------
       0.13   12.3  15.6        7.6    6.5   0.0    2.1  2  Mucin     Mucin-like glycoprotein
       0.62    9.6   1.9       0.63    9.5   0.2    1.7  2  Lin-8     Ras-mediated vulval-induction antagonist
        3.6    8.0  15.4         19    5.7  10.4    2.4  2  MGC-24    Multi-glycosylated core protein 24 (MGC-24), sialom


Domain annotation for each model (and alignments):
>> DAD  DAD family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  153.5   4.1   4.8e-49   2.2e-45       2     109 .]      47     173 .]      46     173 .] 0.95

  Alignments for each domain:
  == domain 1  score: 153.5 bits;  conditional E-value: 4.8e-49
                 HHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHHHHHHHT--SSCHHHHHHHHHHHHHHHHHHHHHHHHH.....................S..-- CS
         DAD   2 keilkellesYlkktpkrlkliDafllflvlvgvlqfvYcvlvgnfpfnaflsgfiatvgqfvLtvsLRlqln...................aenkkef 81 
                 +ei++++l++Y+++tpkr+ l+Daf+++lvlvg++qfvYcv++gn+pfnafl+gf+a+vgqfvLt+sLR+q++                   ++++k++
  EEA21716.1  47 AEIAQHILNRYFAQTPKRTFLLDAFMVYLVLVGGIQFVYCVVAGNYPFNAFLAGFSAAVGQFVLTASLRMQTSssststngpisskgktqttSAEQKDT 145
                 68999********************************************************************99999999999999998887777779 PP

                 TT--TTHHHHHHHHHHHHHHHHCCCH-X CS
         DAD  82 keisperafadfvlasliLhfvvvnFig 109
                  e+s+erafad++++sliLhf+++nFi+
  EEA21716.1 146 LEVSHERAFADYIFGSLILHFFCINFIN 173
                 9**************************8 PP

>> Mucin  Mucin-like glycoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0  14.6     0.005        22      62      96 ..      12      46 ..       2      52 .. 0.62
   2 ?    6.5   0.0    0.0017       7.6      49      83 ..     111     145 ..      68     159 .. 0.56

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.005
       Mucin 62 ttasttittkttkattttttttttttateaPsdav 96
                ++a++  t  tt ++tt+++ttttt+a+ +P  +v
  EEA21716.1 12 SAAAAVSTPSTTSTSTTSSSTTTTTAAPLSPKASV 46
                33444444555666666677777788888887555 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0017
       Mucin  49 ttttkppttttttttasttittkttkatttttttt 83 
                 t +++  t++  t+t+ +  +   t++t++ +++t
  EEA21716.1 111 TASLRMQTSSSSTSTNGPISSKGKTQTTSAEQKDT 145
                 22333333334444334433333333333333333 PP

>> Lin-8  Ras-mediated vulval-induction antagonist
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.2   0.00014      0.63     222     291 ..       6      76 ..       1      78 [. 0.64
   2 ?   -0.9   0.1      0.21   9.5e+02     233     257 ..     119     143 ..     103     159 .. 0.47

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00014
       Lin-8 222 qsfgsaeqqlessssrtssassssssaapsstaakdfeeemkqIteqa.kriareqPervkliRkaLfktv 291
                 q+ +s+  + + s  +t+s+s+ sss+   ++a  + ++++  I++++ +r +++ P+r+ l+   +   v
  EEA21716.1   6 QQASSPSAAAAVSTPSTTSTSTTSSSTTTTTAAPLSPKASVAEIAQHIlNRYFAQTPKRTFLLDAFMVYLV 76 
                 333333333444444455555555555666666677788888999997589********999877666666 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.21
       Lin-8 233 ssssrtssassssssaapsstaakd 257
                 ssss +++ ++ss+ + + ++a+++
  EEA21716.1 119 SSSSTSTNGPISSKGKTQTTSAEQK 143
                 2222222222233222222222222 PP

>> MGC-24  Multi-glycosylated core protein 24 (MGC-24), sialomucin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7  10.4    0.0043        19      49     122 ..      14      84 ..       2      89 .. 0.45
   2 ?    4.9   0.2    0.0077        34      69      97 ..     116     144 ..     102     171 .. 0.63

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0043
      MGC-24  49 telcsaaskst.pkptnstaktttkpsstttstsvatsgttnttvtptsqparkstFDaAsFiGGivLvLgvqAv 122
                 ++++s+ s+++ +++++st++tt++p s+ +s +  ++   n         + k tF   +F+  +vLv g+q v
  EEA21716.1  14 AAAVSTPSTTStSTTSSSTTTTTAAPLSPKASVAEIAQHILNRY----FAQTPKRTFLLDAFMVYLVLVGGIQFV 84 
                 22222222222022223333333333333333333333333333....333347788777888888888888876 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.0077
      MGC-24  69 tttkpsstttstsvatsgttnttvtptsq 97 
                  +t++sst+t++  +++g+t+tt + +++
  EEA21716.1 116 MQTSSSSTSTNGPISSKGKTQTTSAEQKD 144
                 34455556666666666666666544433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (173 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1076  (0.0600145); expected 358.6 (0.02)
Passed bias filter:                      500  (0.0278878); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1188.55
//
Query:       EEA21717.1  [L=905]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.3e-17   62.9   0.1    2.3e-17   62.9   0.1    1.8  2  Fungal_trans  Fungal specific transcription factor domain
    7.2e-10   38.8   9.5    1.4e-09   37.9   9.5    1.5  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.9   0.1   2.5e-21   2.3e-17       3     197 ..     273     462 ..     271     484 .. 0.76
   2 ?   -4.1   0.3       0.7   6.3e+03     178     205 ..     706     733 ..     696     749 .. 0.62

  Alignments for each domain:
  == domain 1  score: 62.9 bits;  conditional E-value: 2.5e-21
  Fungal_trans   3 rffsnfhpqfpilhkpsflpkt..ssenssksayaspllllailalGalfsesetkesnssltses.......qefiafplraeilihedfsspsss 90 
                   ++ +n+ p++ ++hkp++ +    +  n  + ++++++l+++i+  +  +++ e+     +l +++       +    + l+ +     ++  +s +
    EEA21717.1 273 TYEQNVAPLLMVVHKPTVRNLIinAAMNGDSLDKSNEALVFVIYLAAVISMPPEQCLA--ELGDDRdttisrfRFATEQALARA-----NLL-NSLN 361
                   67788999***************95555555555555555555555444444444333..333333223333222222223333.....333.4555 PP

  Fungal_trans  91 lwilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPc 187
                   ++ lq+ +l+  +   ++ ++ ++ + +v +rla+ lgLhr+  + g      l+++e e+rrRlww + + D++++ ++G  p++++++ ++++P 
    EEA21717.1 362 INLLQAAVLFTSCVHRLDHNRFVWTMASVILRLATGLGLHRDGTHFG------LSPFETEMRRRLWWHIVIADVRTSEDHGTDPMINEWMYDTRMPL 452
                   999**99999999999999****************************......*******************************99*********** PP

  Fungal_trans 188 ddddlwesdd 197
                   + +d ++  +
    EEA21717.1 453 NINDDDINPE 462
                   9998776554 PP

  == domain 2  score: -4.1 bits;  conditional E-value: 0.7
  Fungal_trans 178 dsqinlpLPcddddlwesddaseetlve 205
                    +qi+lp     d +w+ ++ +  ++++
    EEA21717.1 706 QQQISLPQQSKPDQQWQKSTSNSPYQRD 733
                   4566666444455577777777666665 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.9   9.5   1.6e-13   1.4e-09       1      33 [.      63      93 ..      63      99 .. 0.93

  Alignments for each domain:
  == domain 1  score: 37.9 bits;  conditional E-value: 1.6e-13
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfy 33
                ++C +Cr++Kv+C++  P CsnC+k + eC  +
  EEA21717.1 63 RSCVTCRRRKVRCNKTEP-CSNCVKAGIECI-F 93
                59****************.***********9.4 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (905 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1181  (0.0658709); expected 358.6 (0.02)
Passed bias filter:                      500  (0.0278878); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.81u 0.30s 00:00:01.11 Elapsed: 00:00:00.47
# Mc/sec: 5730.57
//
Query:       EEA21718.1  [L=434]
Description: mannosylphosphorylation protein (Mnn4), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.2e-23   82.7   4.0    7.1e-16   59.0   2.0    2.3  2  LicD      LicD family


Domain annotation for each model (and alignments):
>> LicD  LicD family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.0   2.0     4e-20   7.1e-16       4     103 ..     220     320 ..     218     330 .. 0.82
   2 !   23.5   0.0   2.8e-09     5e-05     189     227 .]     336     374 ..     321     374 .. 0.88

  Alignments for each domain:
  == domain 1  score: 59.0 bits;  conditional E-value: 4e-20
        LicD   4 ngleywLsgGTllGavRhggfIPWDDDiDlqmprkdyerLaevfnq.lilkkedlreaekdknylenfaklldkntsiterkngngkn.........ds 92 
                  + e+w+++GTll + +++ ++PWDDD+D+q   +  + Lae  n  ++l  +d           ++ +++ld n  +++r++ +++n          s
  EEA21718.1 220 LNVETWIMHGTLLAWWWNQKIFPWDDDLDVQVSEPGIHFLAEKYNMtEHL--FDI-------PGVGERKYVLDINPHYIVRTTLDKENvidgrwidtSS 309
                 5889**************************************77773444..222.......23444599999999999999999999999999999** PP

        LicD  93 glyiDIfpldy 103
                 gl+iDI+ +  
  EEA21718.1 310 GLFIDITAVRA 320
                 *******9942 PP

  == domain 2  score: 23.5 bits;  conditional E-value: 2.8e-09
        LicD 189 rnkeilpleelsplkkvkFegvevpipnnydkyLtelYg 227
                 ++ + ++ ++++pl+++ Fegv++++p  y k+L  +Yg
  EEA21718.1 336 KDSHRFQENDIFPLRRTFFEGVPAKVPYAYTKLLADEYG 374
                 578999********************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (434 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       564  (0.0314574); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 2897.61
//
Query:       EEA21719.1  [L=821]
Description: C6 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
     0.0016   17.5   0.0     0.0033   16.5   0.0    1.5  1  Fungal_trans  Fungal specific transcription factor domain
     0.0025   17.9  11.8     0.0025   17.9  11.8    1.8  2  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   3.7e-07    0.0033      33     180 ..     230     374 ..     206     407 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 3.7e-07
  Fungal_trans  33 ayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLlllelyektss..dralherhhgvavrlarsl 127
                   + ++p l+laila  +  ++   + + + +   +         a+ ++    ++  +sl+++q+Ll +++y +  +  ++ +++ +  +a ++a ++
    EEA21719.1 230 RATKPVLFLAILAGTSIAVDVGLANTLNRELLTM--------YAQRFF----FKAEKSLEMVQALLVMNVYYLPPElpSQIQAYQYAHIAATMALEI 314
                   5556666666666666666665555555555444........444444....566666****************99778999999************ PP

  Fungal_trans 128 gLhrnpsyvgkks........lwklweeeaesrrRlwwaaFylDktialklGrppllddsq 180
                   g   ++    k +        + + +e   e+  R+ +a++ l   +a+ ++rp+ll++++
    EEA21719.1 315 GIASRKRTPRKPTpgqgqakpVHRFDEQMVEQ-ARTILACYHLSSNVAMRTRRPNLLPCND 374
                   **9999999888899****9977777776776.7888999999999999999999888875 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9  11.8   2.8e-07    0.0025       1      39 [.      25      66 ..      25      67 .. 0.81
   2 ?   -3.2   0.1       1.1   9.5e+03      23      31 ..     372     380 ..     369     386 .. 0.80

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 2.8e-07
                SS-HHHHHCT---..ST.SSSS-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus  1 haCdnCrkkKvKC..da.kkPaCsnCkklnleCtfysesskr 39
                ++C++Cr+ Kv+C  da +  +C++C+k    C f   +++r
  EEA21719.1 25 RSCESCRSLKVRClpDAnNANQCQRCAKAKRACIFVAPQRRR 66
                59***********555554444************88887776 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 1.1
                 HHHCTHHHC CS
     Zn_clus  23 CkklnleCt 31 
                 C  + +eC+
  EEA21719.1 372 CNDWIKECV 380
                 888999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (821 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1153  (0.0643092); expected 358.6 (0.02)
Passed bias filter:                      604  (0.0336884); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.76u 0.34s 00:00:01.10 Elapsed: 00:00:00.49
# Mc/sec: 4996.33
//
Query:       EEA21720.1  [L=620]
Description: hypothetical protein PMAA_055150 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.037   14.4   2.2      0.037   14.4   0.2    2.0  2  FAM219A          Protein family FAM219A
       0.41   10.7   4.7       0.24   11.4   1.0    2.1  2  Baculo_PEP_C     Baculovirus polyhedron envelope protein, PEP


Domain annotation for each model (and alignments):
>> FAM219A  Protein family FAM219A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.2   4.2e-06     0.037      40     111 ..     330     399 ..     310     408 .. 0.85
   2 ?   -2.7   0.1      0.81   7.3e+03      20      37 ..     554     569 ..     527     578 .. 0.54

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 4.2e-06
     FAM219A  40 aalsqepdeklvsldsdsdeelesryssGyssaeqvnqdlsrqllkdGyrldeiPddedldliPPkalassv 111
                 a l +  ++k   + sdsd+  +s ++ G  sa++ +qd ++         deiP+  ++d  P  +++s+ 
  EEA21720.1 330 AQLRKMYSDKQAHVHSDSDGSEDSVVRTGRRSAHKRKQDHKKAYP--SSECDEIPEQGQMDNSPTTPINSRP 399
                 5678888899999**************************998765..5689****************99985 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 0.81
     FAM219A  20 avesqPkktrkrsvkfnk 37 
                 +  sqP++  +rs++ n+
  EEA21720.1 554 TLPSQPHR--RRSIRNNR 569
                 33344443..45555554 PP

>> Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   1.0   2.7e-05      0.24      15      95 ..      25     101 ..      14     106 .. 0.86
   2 ?    0.0   0.1     0.091   8.1e+02      71      99 ..     139     168 ..     120     179 .. 0.57

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 2.7e-05
  Baculo_PEP_C  15 fldLtnvLnairlqnvqilaqlatlldaietqLnalsedlksllaeldtrldtlltnLtdalnalqdtlrneLtnlnsilt 95 
                    l L  +Lna+     q+ a+l  ++ +i + ++ +s++lk+l+++l+++ +  + +  d+  +++d+ r+  + ++  l 
    EEA21720.1  25 GLRLALLLNAV---ACQV-ANLGVDIHSISKGISLFSTSLKQLVQSLQAEHSVHTRECLDTARQISDQARTVFEEVEDMLE 101
                   46778889999...8889.99****************************99999999999999999999999999987775 PP

  == domain 2  score: 0.0 bits;  conditional E-value: 0.091
  Baculo_PEP_C  71 nLtdalnalqdtlr.neLtnlnsiltnLls 99 
                   +L+ +l  +++ l+  +L+ ++s+l++L+ 
    EEA21720.1 139 ALKLSLMVMTQILHlGRLQEIKSVLNTLTD 168
                   333333333343322355555666665553 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (620 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1588  (0.0885716); expected 358.6 (0.02)
Passed bias filter:                      572  (0.0319036); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.70u 0.29s 00:00:00.99 Elapsed: 00:00:00.46
# Mc/sec: 4036.06
//
Query:       EEA21721.1  [L=856]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.5e-19   68.4   0.0      2e-18   67.3   0.0    1.6  1  GFO_IDH_MocA  Oxidoreductase family, NAD-binding Rossmann fol
  ------ inclusion threshold ------
      0.046   13.7   0.1      0.094   12.7   0.1    1.6  1  BCA_ABC_TP_C  Branched-chain amino acid ATP-binding cassette 


Domain annotation for each model (and alignments):
>> GFO_IDH_MocA  Oxidoreductase family, NAD-binding Rossmann fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.3   0.0   2.2e-22     2e-18       7     119 ..      20     136 ..       4     137 .. 0.83

  Alignments for each domain:
  == domain 1  score: 67.3 bits;  conditional E-value: 2.2e-22
                   TTSHHHHHHHHHHHHTTTTEEEEEEECSSHHHHHHHHHHTTHE....EESSHHHHHTCTTESEEEE-S-GGGHHHHHHHHHHTT-EEEEESSS-SSH CS
  GFO_IDH_MocA   7 GaGkigskhlrplnesqrleevvalldpdaeraeavaesfgve....aysdleelladpeidavivatpngtheelakaaleagkhvllEKPlattv 99 
                   G G  +   + p   s++++++val ++++e+a+++ + ++++    ay + ee+++dp++d++++ +   +h++lakaal a+k+v++E Pl +++
    EEA21721.1  20 GPGSWANLAHLPHLLSSPDYQIVALANSSKEAAQQAIKVYNLPtttkAYGSPEEIANDPDVDLIVISVVVMKHYQLAKAALLAKKNVFVEWPLGANL 116
                   33333222233555555777****************999999988888888********************************************** PP

                   HHHHHHHHHHHHHTS-EEEE CS
  GFO_IDH_MocA 100 eeakelvelaekkgklvsvg 119
                   +e +elv+la+++g++ +vg
    EEA21721.1 117 AESQELVTLAKENGVKTIVG 136
                   ***************99997 PP

>> BCA_ABC_TP_C  Branched-chain amino acid ATP-binding cassette transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.1     1e-05     0.094       4      17 ..      67      80 ..      67      80 .. 0.94

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 1e-05
  BCA_ABC_TP_C  4 AeGtPaEvrndPrV 17
                  A G+P+E+ ndP+V
    EEA21721.1 67 AYGSPEEIANDPDV 80
                  77***********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (856 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       580  (0.0323498); expected 358.6 (0.02)
Passed bias filter:                      539  (0.030063); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.68u 0.29s 00:00:00.97 Elapsed: 00:00:00.44
# Mc/sec: 5877.31
//
Query:       EEA21722.1  [L=539]
Description: uracil permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.9e-89  298.4  40.1    1.1e-88  298.0  40.1    1.2  1  Transp_cyt_pur  Permease for cytosine/purines, uracil, thiami


Domain annotation for each model (and alignments):
>> Transp_cyt_pur  Permease for cytosine/purines, uracil, thiamine, allantoin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  298.0  40.1   6.1e-93   1.1e-88       3     422 ..      48     474 ..      46     507 .. 0.95

  Alignments for each domain:
  == domain 1  score: 298.0 bits;  conditional E-value: 6.1e-93
  Transp_cyt_pur   3 peeeRtwktlnlfsiWlganlnintwvigalglalgLnwwqsvlviivgnligaifvallglaGakyGlpfpilsRasfGirgsllplllrvvia 97 
                     p e+Rtwk   ++  Wl+++l+ + w iga+ l++gL w ++v +  +g++i+a ++a++g+ Ga + +pfpi +RasfG  ++ + +++r+v+a
      EEA21722.1  48 PVERRTWKSSSIIGYWLSDILSAQSWEIGASVLQIGLTWREAVYCCTLGSFIMALPIAFNGAPGAFLRVPFPIWIRASFGYHFAKFAIVVRLVTA 142
                     679******************************************************************************************** PP

  Transp_cyt_pur  98 ivwfgvqawiGsealllmlgkifgkwleigg...ailgtsltelvtffifwvvslvivllgvskirkffviaallvpvaafgfliwalvkaeg.G 188
                     + w+++q+++G++a+++ml  i+++  +i++   a+ g++  +l++ + fw++++++v+  ++k++ ffv++a+++  aa g  i + + a+g G
      EEA21722.1 143 LFWTSIQTYTGGTAVTVMLTAIWPSYKNIPNylpASAGITSQGLLSHLLFWLAQVPFVVIRPHKLKWFFVFKAFITITAATGTTIAICRMAHGsG 237
                     *********************************************************************************************** PP

  Transp_cyt_pur 189 pvldkavklg.kse..lflsavagvlagfatlilnapDFtryaktkkssvkiqlvavpllftlllligilvaaaakaayganawspldilakfde 280
                     ++ d++  ++ +++  l++s++++  ++++t+ +n++DFtry+k+++  ++iq++++pl  + l+l+gi+ a+a+k +yg+ +w+p+ +   + +
      EEA21722.1 238 DIWDQKPTVSgWTKawLIVSTLNAQTGSWSTVGTNISDFTRYVKNPRT-IYIQTIVFPLICIWLALLGIISASASKRVYGEYVWDPVTLASYWTS 331
                     *****9999966669889999*************************95.889***********************************88888888 PP

  Transp_cyt_pur 281 t...agvllililvalaqlgvnisanllsagldlaallPkkinikrgsliaav.ialvivpwkllssssklftaflsllavflspvagviiadyf 371
                         +g +   +   +aq+gv++san++sa +dl+ l+Pk++n++r +l++++ +a v+vpwk   s+++  ++f+  l++fl p++++ iady+
      EEA21722.1 332 PagrLGAFYCGFAWIIAQIGVTVSANIISASNDLSSLFPKYLNLRRSALMVSItAAWVMVPWKIVTSAES-LLNFMASLGIFLAPIIAISIADYW 425
                     899999**********************************************945689************.************************ PP

  Transp_cyt_pur 372 vvrrgylklaalytrrrgsaYwyrkgvNwravaayivGiaaglvgvagsvg 422
                     +v+r+++ +  ly   + ++Y yr g+Nwra  a iv+ia+ ++ +  ++ 
      EEA21722.1 426 IVKRRRVDVPGLYQ--PHGRYAYRHGFNWRACTALIVSIAPTMPSLVHNIN 474
                     **************..*************************9998655444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (539 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       671  (0.0374254); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.41
# Mc/sec: 3933.24
//
Query:       EEA21723.1  [L=1106]
Description: DUF726 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   3.1e-126  421.0   2.9   4.2e-126  420.5   2.9    1.1  1  DUF726    Protein of unknown function (DUF726)
  ------ inclusion threshold ------
        4.6    8.1   6.0         14    6.6   1.0    3.0  2  FliT      Flagellar protein FliT


Domain annotation for each model (and alignments):
>> DUF726  Protein of unknown function (DUF726)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  420.5   2.9  4.6e-130  4.2e-126       5     343 .]     508     843 ..     502     843 .. 0.99

  Alignments for each domain:
  == domain 1  score: 420.5 bits;  conditional E-value: 4.6e-130
      DUF726   5 rylliglAglaGgaligltggLaaPlvaagigallaglGltgsaafLasvggsavitallgaagAklsvkkmkkrvkeikdFefiplseqirlksltvt 103
                 +y+++glA+++Gg++igl++gL+aP+++ag++a ++++G++g+ afL+++gg+a+i++  + +g   + k  ++r++++++Fe++pl++++r+ +l+vt
  EEA21723.1 508 KYVIMGLATVGGGLVIGLSAGLLAPVIGAGLAAGFTTIGISGTGAFLGGAGGTALIASGATLTGTYSGLKASHRRTGAVQTFEYRPLHNNQRV-NLIVT 605
                 799****************************************************************************************98.***** PP

      DUF726 104 vsislelsdeddvtapwralakaekdlYalkwEvelLkelGkaletilasealsvakqeilkrtvlaslvaaltWPlaLlkvakildnpwnvsleraak 202
                 vs+++ +++ ddv+ p+++++++++dlY++ wE+e+L+++G+++ +ila+eal++ +q++l++t+l++l+ al+ P+ L+k+a+++dnpwnvsl ra++
  EEA21723.1 606 VSGWM-TGKVDDVRLPFSTVDPIMGDLYSVFWEPEMLQSMGSTI-NILATEALTQGLQQVLGSTILTALMGALQLPIVLTKLAYLIDNPWNVSLVRANA 702
                 *****.**************************************.****************************************************** PP

      DUF726 203 aGklLAdallsraqGeRpvtLiGfslGARviyvCLlelakkkalglvenvillGaPvtteakvwlkvrsvvsgRlvnvysenDylLgflyRtssaqf.r 300
                 aG +LAd ++sr+ G+Rp+tL+GfslG Rvi++CL+elak+ a+glv+nv+++G P+++++  +lkvrsvv gR+vn+ys+nD++Lg+l+R++s ++ r
  EEA21723.1 703 AGLILADSIMSRNLGKRPITLLGFSLGSRVIFSCLKELAKRGAYGLVQNVYMFGSPIVANKDDYLKVRSVVVGRFVNGYSSNDWILGYLFRATSGGImR 801
                 ************************************************************************************************99* PP

      DUF726 301 vaglqrieldvekvenvdvselvegHldYrkklkkilkaigle 343
                 vagl+++  +++++en+dv+ lv+gH++Yr  ++++l+++g+e
  EEA21723.1 802 VAGLGPVL-GIPGMENFDVTRLVSGHMNYRAAMPRLLREVGWE 843
                 *******9.7******************************996 PP

>> FliT  Flagellar protein FliT
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   1.0    0.0015        14       1      24 [.     482     505 ..     482     507 .. 0.93
   2 ?    2.7   0.3     0.026   2.3e+02      13      52 ..     822     873 ..     815     883 .. 0.72

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.0015
                 HHHHHHCT-HHHHHHHHHHHHHHH CS
        FliT   1 mleaAragdWdelaaleaerqqlv 24 
                 m++aA+++ Wde + +e++r +++
  EEA21723.1 482 MEQAAEKETWDESEHMEQRRKKAL 505
                 99******************9886 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.026
                 HHHHHHHHHHHHHHHHCS-............-ST--HHHHHHHHHHHHHHHH CS
        FliT  13 laaleaerqqlverlreld............aaplspaereekrellrrila 52 
                 l++  +++++++ rl ++             ++p +++ +e++rel+r+i +
  EEA21723.1 822 LVSGHMNYRAAMPRLLREVgwevlsdefaeiEDPDPDNHAERQRELIREIDE 873
                 555555666666666666666666666677779999************9955 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1106 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       974  (0.0543254); expected 358.6 (0.02)
Passed bias filter:                      419  (0.02337); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.78u 0.27s 00:00:01.05 Elapsed: 00:00:00.44
# Mc/sec: 7520.78
//
Query:       EEA21724.1  [L=493]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.5e-13   49.6   0.1    1.1e-12   48.0   0.0    1.9  3  DDE_1        DDE superfamily endonuclease
      5e-05   23.2   2.8    0.00012   22.0   0.0    2.8  3  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
        7.1    6.8  10.0       0.27   11.3   3.7    1.8  2  Med9         RNA polymerase II transcription mediator complex


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0       1.5     9e+03      56      71 ..      21      36 ..      12      45 .. 0.72
   2 !   48.0   0.0   1.8e-16   1.1e-12       3     135 ..     117     250 ..     115     267 .. 0.89
   3 ?   -2.7   0.1      0.67     4e+03     116     136 ..     371     391 ..     344     426 .. 0.48

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 1.5
       DDE_1 56 ssifeeWLkvfdkrle 71
                 +++ +W ++f krl 
  EEA21724.1 21 PKLGDRWVHRFLKRLP 36
                6788899999988875 PP

  == domain 2  score: 48.0 bits;  conditional E-value: 1.8e-16
       DDE_1   3 rltvllcanaagsekLkplvigkaksprafkngektkkkldveyksnrkawltssifeeWLkvfdkrle..aekrkilLlldssrshetvel.leselq 98 
                 +l+++++ + a +  +++ +i+ +k + ++++  +   + +++ ++++ +   ++i  eWL++fd+ ++  a ++  lL +ds+++h t e+   + ++
  EEA21724.1 117 ELVTVIEGINAAGSAIPLFLIFTGKVILESWF--QYLTEDEWKVTITESGFSNNEIAYEWLQHFDQHTReqAGNNWRLLTMDSHTAHLTREFmDYCLEH 213
                 455566666666779*****************..666777899999***********************98889999***************99999** PP

       DDE_1  99 niklvflPassasllqPldqgvvselKarYrrqllqa 135
                 +i  + +Pa++++llqPld   + + K+  rr+++++
  EEA21724.1 214 KIVPFRFPAHTTHLLQPLDGMPFLHYKRIHRRAINEQ 250
                 *******************988888888888877665 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 0.67
       DDE_1 116 ldqgvvselKarYrrqllqal 136
                 ld +  ++  ++  ++++  l
  EEA21724.1 371 LDGSLTQAHIKEQQQEQIDRL 391
                 333333332222222222222 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.0   0.0     2e-08   0.00012      26      63 ..       1      38 [.       1      41 [. 0.91
   2 ?   -0.1   0.2      0.16   9.5e+02      26      56 ..     142     178 ..     138     183 .. 0.60
   3 ?   -4.0   0.1       2.7   1.6e+04      21      30 ..     374     383 ..     369     390 .. 0.75

  Alignments for each domain:
  == domain 1  score: 22.0 bits;  conditional E-value: 2e-08
                 HHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHTS-- CS
  HTH_Tnp_Tc5 26 lirekAqelaslaadlgepdfkaSkgWldrFkkRhglk 63
                 +i+++A++++++ + +   ++k++ +W++rF+kR++++
   EEA21724.1  1 MIQNYAENVLQNMHPNAANPPKLGDRWVHRFLKRLPPA 38
                 8*********88899999****************9875 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.16
                  HHHHHHHHHH......HHSSSCT-TT-S--CHHHHHH CS
  HTH_Tnp_Tc5  26 lirekAqela......slaadlgepdfkaSkgWldrF 56 
                  +i e + +++      +++++ g ++    ++Wl++F
   EEA21724.1 142 VILESWFQYLtedewkVTITESGFSNNEIAYEWLQHF 178
                  5555555555555555555555555566666677777 PP

  == domain 3  score: -4.0 bits;  conditional E-value: 2.7
                  --SCHHHHHH CS
  HTH_Tnp_Tc5  21 pitgelirek 30 
                  ++t++ i+e+
   EEA21724.1 374 SLTQAHIKEQ 383
                  6788888886 PP

>> Med9  RNA polymerase II transcription mediator complex subunit 9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   3.7   4.6e-05      0.27       7      70 ..     340     402 ..     335     404 .. 0.90
   2 ?   -3.7   0.4       2.3   1.4e+04      32      40 ..     435     443 ..     428     444 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 4.6e-05
        Med9   7 ydilksiekdpnlsskdletktgelrhkLkkarelirelpgidrsveeqeaeieeleeqlakKr 70 
                 y++ +si+k    + +++et++ ++r  Lkk+     +  +i + ++eq +++++l+e+  +K+
  EEA21724.1 340 YKLQRSITKVD-AQLNKIETAIPGIRRSLKKILDGSLTQAHIKEQQQEQIDRLQTLNERKSAKK 402
                 77888998888.999********************9999*****************99988887 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 2.3
        Med9  32 rhkLkkare 40 
                 r++Lk+ re
  EEA21724.1 435 RKRLKELRE 443
                 677777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (493 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1311  (0.0731218); expected 358.6 (0.02)
Passed bias filter:                      718  (0.0400469); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.61u 0.26s 00:00:00.87 Elapsed: 00:00:00.41
# Mc/sec: 3611.57
//
Query:       EEA21725.1  [L=500]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-29  102.5   0.0    3.8e-29  101.3   0.0    1.6  1  RTC4      RTC4-like domain
  ------ inclusion threshold ------
        2.1    7.7  11.8        3.5    6.9  11.8    1.3  1  U79_P34   HSV U79 / HCMV P34


Domain annotation for each model (and alignments):
>> RTC4  RTC4-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.3   0.0   4.2e-33   3.8e-29       7     120 ..     369     481 ..     364     482 .. 0.90

  Alignments for each domain:
  == domain 1  score: 101.3 bits;  conditional E-value: 4.2e-33
        RTC4   7 vyrdeakeavkksgkrklskeekrkldlekftpGYYGlkgqriiseeilkkfkkelrkravkdklvsargvsdFvqaVLvPEvavrLimeDmkvseeeA 105
                 ++r ++++++++ g++k+ k + +  + e +++GYYG+kg++++ + +++k++ +lr+ a++dk+++a+g+++++qaVLvPE++v+Li++Dmkv++++A
  EEA21725.1 369 FFRGRFESTLND-GQAKVFKFDLEGDSTEGLSCGYYGPKGANKMLNFVTSKYSGKLRQLAATDKVIKAAGAAAYAQAVLVPELTVLLIKKDMKVDSQDA 466
                 566677777777.7767766667777899********************************************************************** PP

        RTC4 106 reileesaeyGelvn 120
                 r+il+es+++G  +n
  EEA21725.1 467 RQILRESTDIGLRLN 481
                 ***********9887 PP

>> U79_P34  HSV U79 / HCMV P34
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9  11.8   0.00039       3.5     131     214 ..      49     134 ..      36     148 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.00039
     U79_P34 131 lknlGdskcveklekegraldrkkaddeqrkrsgkqkekrkvedidkkkedekrkeeerkks..dedkssdkkeeldedPkekrqk 214
                 +    d + +++ e+e+ a   kk++ e+rk   +q + +  +d++kk   +++++ +rk +  +++ ++d+ +++d       qk
  EEA21725.1  49 VEPATDDEPLSSSEEESEAERVKKQELEERKEEDRQFQEKVAKDTNKKGAGKRKRDGRRKSNppSSNARTDEDNGYDIFGMRSSQK 134
                 55566777889999******************99999999999999999888888888888755689999**99999877777777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (500 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1624  (0.0905795); expected 358.6 (0.02)
Passed bias filter:                      641  (0.0357521); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.27s 00:00:00.89 Elapsed: 00:00:00.41
# Mc/sec: 3641.76
//
Query:       EEA21726.1  [L=777]
Description: glutamate carboxypeptidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      4e-31  107.6   0.0    6.6e-31  106.9   0.0    1.4  1  TFR_dimer      Transferrin receptor-like dimerisation domain
      3e-20   72.8   0.0    5.8e-20   71.8   0.0    1.4  1  Peptidase_M28  Peptidase family M28
    9.7e-12   44.8   0.9    6.6e-11   42.1   0.9    2.2  1  PA             PA domain
  ------ inclusion threshold ------
      0.049   13.1   0.0      0.089   12.2   0.0    1.3  1  Nicastrin      Nicastrin


Domain annotation for each model (and alignments):
>> TFR_dimer  Transferrin receptor-like dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.9   0.0   1.5e-34   6.6e-31       2     120 ..     651     776 ..     650     777 .] 0.93

  Alignments for each domain:
  == domain 1  score: 106.9 bits;  conditional E-value: 1.5e-34
   TFR_dimer   2 sldpLeeaikkfkkaaeefdkwadkwed..........vggaessllavrkrrkiNdklmrferafldpeglpgrpwykHvvfgpslwtgyagatFPgi 90 
                 s++pLe+ai+ f +aa efd++a+k+ +          + ++ + +++vr   +iN+k++++er+fl++ gl+gr+wykHvvf+p+lwtgyagat+Pg+
  EEA21726.1 651 SFEPLEQAIAGFYDAAVEFDAYAAKVGSelgqevpwyhWWKKLQLWYKVR---AINTKYKTLERKFLYEAGLDGRSWYKHVVFAPGLWTGYAGATYPGL 746
                 8************************9999988776554257888889998...********************************************** PP

   TFR_dimer  91 rdaieegdweeaqeqisivakaiesaaelL 120
                 ++++++g++++a ++ +i+ + +  a++l+
  EEA21726.1 747 VESLDDGNVTNAVRWSEIIRERLGMATKLI 776
                 ************************999876 PP

>> Peptidase_M28  Peptidase family M28
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.8   0.0   1.3e-23   5.8e-20       1     180 [.     399     586 ..     399     591 .. 0.84

  Alignments for each domain:
  == domain 1  score: 71.8 bits;  conditional E-value: 1.3e-23
                    EEEEEESTTCESEEEEEEEE--B-TTTTCCT---TTTTHHHHHHHHHHHHHCHH...GGCCSSEEEEEEEESSCSGSSHHHHHHHH.HHC..CCTT CS
  Peptidase_M28   1 NviatlegkatdevlllgAHyDsvgvgrgpifvGAdDnAsgvaalLelarvlaa...sgsrpkrgvrflffdaEEagllGSkafak.akp..elkk 90 
                    Nvi+ + g+  dev++lg H D +         GA D  sg aal e++r + +    g +p r+++f+ +d+EE+gl+GS+ +++ +     + +
     EEA21726.1 399 NVIGVITGTILDEVVILGNHRDAWVA---G---GAGDPNSGSAALNEVVRGFGEalkAGWKPLRTIVFASWDGEEYGLVGSTEWVEeN-LpwLNVA 487
                    99****99999**************5...7...9*******************99998889************************853.3457778 PP

                    EEEEEEECS-SSSS--EEEHHHHHHCHHHHHHHHHHHHHTT-TTSCCEEEEESSTT-.....STTHHHH.TTT--EEEE....CTSSS-TTTTSTT CS
  Peptidase_M28  91 iaavlnlDmvgsggkellfesgdkssselekelkalakpvgraaaedpfdersgrgr.....sDhspfl.kagvpvldl....aetgfpevyHtpr 176
                     a+++n+D  +s g+ + +  ++   +++ + ++++ +p ++ + + ++d  +g++      sD++pf+  ag+p +++     +t++ ++yH++ 
     EEA21726.1 488 NAVYINVDV-ASCGPVFKVDGSPLLNKAVHEVTSTVQSPNQTVKGQSVLDAWGGYIAslgsgSDYTPFQeFAGIPSVSFgfvgGKTDAVYHYHSNY 582
                    899*****8.7888999985555555556555566666666666668888888777778888*******4577******999999999******** PP

                    SSGG CS
  Peptidase_M28 177 Dtld 180
                    D +d
     EEA21726.1 583 DSFD 586
                    *998 PP

>> PA  PA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.1   0.9   1.5e-14   6.6e-11       1      71 [.     206     282 ..     206     343 .. 0.89

  Alignments for each domain:
  == domain 1  score: 42.1 bits;  conditional E-value: 1.5e-14
          PA   1 vtgplVyscfagygisadfe.....gvdvkGkivLvqr...tfaeKarnAqaaGAagviivndge.lgaatgasgnegep 71 
                 vt+p V   +a+ g++ d++     g++v+Gkiv+v+     ++ K++ Aq+ GA+gv+i++d++ +g+ t+ +g+e +p
  EEA21726.1 206 VTAPFV---YANFGTHQDYQdlvdaGISVEGKIVIVKYggiFRGLKVKGAQDLGAVGVVIYSDPQeDGDITELNGYEAYP 282
                 79****...***************************7577777******************9988766666666666655 PP

>> Nicastrin  Nicastrin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0     2e-05     0.089      19      73 ..     424     478 ..     420     481 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2e-05
   Nicastrin  19 slGaessvsslvallaaaealskllkdisnlkrnvlFvffnGEsydYiGSqrfvy 73 
                 + Ga ++ s+ +al  +++ + ++lk+  +  r ++F+ ++GE y+ +GS   v 
  EEA21726.1 424 AGGAGDPNSGSAALNEVVRGFGEALKAGWKPLRTIVFASWDGEEYGLVGSTEWVE 478
                 67999999******************************************98875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (777 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       443  (0.0247086); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.44
# Mc/sec: 5311.55
//
Query:       EEA21727.1  [L=525]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.5e-31  108.0  17.2    4.5e-31  108.0  17.2    1.8  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  108.0  17.2   2.5e-35   4.5e-31       1     353 []      16     471 ..      16     471 .. 0.80
   2 !   12.9  19.2   2.2e-06     0.039      23     176 ..     348     510 ..     336     521 .. 0.74

  Alignments for each domain:
  == domain 1  score: 108.0 bits;  conditional E-value: 2.5e-35
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispse....igllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvl 94 
                 l+++ f     ++ ++p lp  ++e+ g+ + e    +g+  +++a  ++++++p+G +sdr+Gr+ ++llgl+++ +++l++ f s +  +ll++r++
  EEA21727.1  16 LAICRFAEPVVYTSVLPYLP-EMMESVGVRKNEiakwVGISSAVVASCQCIMAVPWGTFSDRVGRKYTILLGLTSTMFFSLVFGF-SRSLtTLLISRAF 112
                 5799999999**********.899*********7555555666677788******************************888889.77777******** PP

       MFS_1  95 qGlgagalfpagaaliadwfpk.eergraigllsagfslGailgpllgglla.sslg...............Wravfyilaivsllafv..lfllllpe 174
                  Gl+ g +  ++ +++a+++ + e +++a++++ + +s+G+i+gp++gg+la  ++                +     +  i+s+++fv  +   +l+ 
  EEA21727.1 113 LGLMNGNVG-IIRTMVAELVREkELQPLAFSMMPLVWSIGSIFGPAFGGALAnPAVKhpeifgnweifkkypF----ALPNILSAIFFVvgITTGFLFL 206
                 ****75555.555666666666599***************************55555*******888855444....5555555555555555566666 PP

       MFS_1 175 epperkrkspkeee.................................................................kgtgpaplvpawkallkdpv 208
                 e++ ++rk +++ +                                                                 + +++   ++ +k +++++ 
  EEA21727.1 207 EETLESRKHKRDYGlilgrtltqscsskrskplhapavneqtgllasdeesttraesndtissktttygtndsspdydiVEPKKNTRSK-FKTIFTPQS 304
                 66666666555555669999999999999999999999999999999999999999999999999999999888877765555555555.99******9 PP

       MFS_1 209 lwillialllfffgfsglltllply...................lqevlglsglllaglllallalvgail.allagrlsdrlgr.rrrlllallllll 286
                  +  li+  + ++ ++g+ +l+p++                   + + +gl+    +g+l+ l +++g+ + ++++ + ++r+g  r+++++a+ + ++
  EEA21727.1 305 TL-TLIVYGMLAMHNMGFDSLFPVFlhhpqqdlvnnpdvelpfkFTSGFGLG-SQAIGILYTLNGVIGMLVqFIFFPFCARRYGVlRCFRTVAVCFPFV 401
                 97.66666666668999*******8777777777777766664445555555.7889999999999998887778888889999988888888888888 PP

       MFS_1 287 aalglallavtssavllllvlvl.....iGfglgfvfpsllalasdlappeeagtasglfntagslggalgp 353
                  ++  +l+  ++s +++++ l+l     +G++++ ++++ll+ +++++  +  gt++g+  +++++g+a+gp
  EEA21727.1 402 YFITPFLVLIPESMSMSMVYLLLttkmiLGMFAFPCTTILLTNTASSL--KILGTLNGVGVSISAIGRAVGP 471
                 888888888888888888866666777777755555677777777777..8*******************98 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 2.2e-06
       MFS_1  23 laedlgispseigllltlyalgaavaslplGrlsdr.fGrrrvlllglllfalglllll.f.a........sslwlllvlrvlqGlgagalfpagaali 110
                  ++ +g+  ++ig+l+tl ++  ++ ++++ ++  r +G  r++ + +++f +  ++++ f +        s ++lll   ++ G++a   fp   +l+
  EEA21727.1 348 FTSGFGLGSQAIGILYTLNGVIGMLVQFIFFPFCARrYGVLRCFRTVAVCFPFV-YFITpFlVlipesmsmSMVYLLLTTKMILGMFA---FPCTTILL 442
                 466789999999999999999999999888666555499999999999999999.555555423445455444557888888888886...99999999 PP

       MFS_1 111 adwfpk.eergraigllsagfslGailgpllgg...lla.sslg.Wravfyilaivsllafvlfllllpeep 176
                 +  ++  +  g  +g+  + +++G ++gp+l g     +   lg    +++il++++++a++    +++ e+
  EEA21727.1 443 TNTASSlKILGTLNGVGVSISAIGRAVGPALVGeafT-VgVKLGyVIMPWWILTALTVVAMI---PVFWIEE 510
                 9999998999999999999999999999888886531.223333466669999999999988...4444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (525 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       787  (0.0438954); expected 358.6 (0.02)
Passed bias filter:                      434  (0.0242066); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.64u 0.32s 00:00:00.96 Elapsed: 00:00:00.49
# Mc/sec: 3225.69
//
Query:       EEA21728.1  [L=112]
Description: UPF0136 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-20   73.6   8.1      2e-20   73.3   8.1    1.1  1  Tmemb_14  Transmembrane proteins 14C


Domain annotation for each model (and alignments):
>> Tmemb_14  Transmembrane proteins 14C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.3   8.1   1.1e-24     2e-20       5      90 ..      13      98 ..       9     101 .. 0.92

  Alignments for each domain:
  == domain 1  score: 73.3 bits;  conditional E-value: 1.1e-24
    Tmemb_14  5 aygallavGGilgYlkagSvpSLiaGlllGallllagyllsknkka.kelslvislvlllvmgkrllktrkfmpaglvavlsalmll 90
                a++al+++GGi+gY+++gS+pS++aGl +Gal+ll+  +l++n+ + +e+ l++s+vl++++++r+l+ rk++p++l++v +++ l+
  EEA21728.1 13 ALSALTSLGGIIGYARTGSIPSIVAGLSVGALYLLSLLRLRSNQPYaVEIGLLASTVLAGSSVPRALRLRKPVPIALSVV-ATYGLV 98
                789***************************************************************************55.444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (112 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       320  (0.0178482); expected 358.6 (0.02)
Passed bias filter:                      211  (0.0117686); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.36u 0.26s 00:00:00.62 Elapsed: 00:00:00.40
# Mc/sec: 831.97
//
Query:       EEA21729.1  [L=470]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.5e-07   29.5   2.0     0.0078   17.0   0.1    2.5  2  zf-C2H2_4      C2H2-type zinc finger
    0.00031   21.0   2.8      0.012   16.0   0.1    2.4  2  zf-C2H2        Zinc finger, C2H2 type


Domain annotation for each model (and alignments):
>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.9   0.2   3.8e-05      0.34       2      24 .]      19      41 ..      18      41 .. 0.95
   2 !   17.0   0.1   8.7e-07    0.0078       1      24 []      42      65 ..      42      65 .. 0.98

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 3.8e-05
   zf-C2H2_4  2 kCpiCgksFsskkaLlrHlkthH 24
                +C +C + F + k L +H k+ H
  EEA21729.1 19 WCYYCERDFDDLKILISHQKAKH 41
                6*******************999 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 8.7e-07
   zf-C2H2_4  1 fkCpiCgksFsskkaLlrHlkthH 24
                fkC+ Cg++ ++  +L+ H+ ++H
  EEA21729.1 42 FKCERCGRRLNTAGGLSVHMSQVH 65
                8********************999 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.1   0.3     0.004        36       3      23 .]      20      41 ..      20      41 .. 0.94
   2 !   16.0   0.1   1.4e-06     0.012       1      23 []      42      65 ..      42      65 .. 0.97

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.004
                ETTTTEEESSHHHHHHHHHC.C CS
     zf-C2H2  3 CpdCgksFkrksnLkrHirt.H 23
                C +C + F +   L +H++  H
  EEA21729.1 20 CYYCERDFDDLKILISHQKAkH 41
                99***************99877 PP

  == domain 2  score: 16.0 bits;  conditional E-value: 1.4e-06
                EEETTTTEEESSHHHHHHHHHC.C CS
     zf-C2H2  1 ykCpdCgksFkrksnLkrHirt.H 23
                +kC+ Cg++ ++   L +H++  H
  EEA21729.1 42 FKCERCGRRLNTAGGLSVHMSQvH 65
                8*******************9988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (470 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       975  (0.0543812); expected 358.6 (0.02)
Passed bias filter:                      563  (0.0314016); expected 358.6 (0.02)
Passed Vit filter:                        86  (0.0047967); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.27s 00:00:00.91 Elapsed: 00:00:00.42
# Mc/sec: 3383.22
//
Query:       EEA21730.1  [L=878]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0012   17.5   9.2     0.0012   17.5   9.2    2.5  2  Rrn6      RNA polymerase I-specific transcription-initiation 


Domain annotation for each model (and alignments):
>> Rrn6  RNA polymerase I-specific transcription-initiation factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    1.0   1.6    0.0063   1.1e+02     678     849 ..     234     482 ..      88     484 .. 0.65
   2 !   17.5   9.2   6.7e-08    0.0012     670     831 ..     550     742 ..     502     746 .. 0.64

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.0063
        Rrn6 678 sssssssssssssedpelsr.edpldalsrytklikssptslsrsvsniLshWelg.sdpaeydwqrtesale.aeeq..................... 752
                 ++ +  ss++++ e  +l++ e+ ld+l++++ + ++    ++++v   L  W+ +    +e+++++t++  + ++++                     
  EEA21730.1 234 RPDPYLSSTAEKGEFLKLTPvEQFLDSLNDFESMPTDQLHAAAQNVYHALKTWQDEwMAIEELNKRVTNKPKKsSNPRaldpievfqdkreamlygyky 332
                 244444444444444444447777777888988888888888899999999999889888888999998888843333777777777777788888888 PP

        Rrn6 753 .................................rqrarrkrekrrrrkeklklasraeasssssssqssssksssssssqlpsssqvptlpd....... 811
                                                           + r+ + +         + + +   + +++ +++ +  +p+ +++p  p        
  EEA21730.1 333 dptihepkkreannettfkcqdpfvqggfrptaA--------QLRKMQTE---------AGKNNINPDGFKTMTRNGQEYVPKFQDPPLIPFdsrgstn 414
                 8887775554444444444444443222222221........11111111.........1111111122222222333333333333333335566666 PP

        Rrn6 812 ...........fslsmqissSQvvsss....................mSQperGrFgsRpakkKKKRka 849
                            +  ++++  S + ++s                    ++Q+ + + g Rp   KK++++
  EEA21730.1 415 rkrklpqgeiaALRQPSVHDSTTAFESdldgqpfkrvtrsvnktenpQTQTAPPSPGPRPH-GKKRKAR 482
                 6666666777733445666677666667888888888888888888888888556688876.4444444 PP

  == domain 2  score: 17.5 bits;  conditional E-value: 6.7e-08
        Rrn6 670 lssslssss........ssssssssssssedpelsr....................edplda.lsrytklikssptslsrsvsniLshWelg.sdpaey 738
                 l+s++ss++        +              +l++                    e    a l+r +k+++s++++   ++  +L+hW++   d ++ 
  EEA21730.1 550 LTSVASSEQadmtpapmP--------------ALAPaapgappalaalpqplaepgEVLSEAeLRRRDKIANSKNPR---RTIAMLDHWDNFhKDGRTR 631
                 222333333444433220..............222244444445555666777776555566799999999999888...7*********999999999 PP

        Rrn6 739 dwqrtesale....aeeq.rqrarrkrekrrrrkeklklasraeasssssssqssssksssssssqlpsssqvptlpdfslsmqissSQvvsss..... 827
                   +rt+++ e    a+e+ r + + k++k+r+r+       ++ +++  s + +++ ++ +++s+ +++++++ t++  ++s+q+ s Q+   s     
  EEA21730.1 632 KPKRTKEQMEadrvADESrRANGQGKAPKKRKRRAA-----TTTTTTVDSPAIKQQGTTATATSTAIAATATTATTST-TVSLQPISIQPAATSattap 724
                 999999999966653333333333333333333333.....4555555556666677888888999988888888888.67778878777777777777 PP

        Rrn6 828 ..............mSQp 831
                               m+Q+
  EEA21730.1 725 vapppppppppariMTQT 742
                 777777888888888885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (878 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       960  (0.0535445); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.79u 0.29s 00:00:01.08 Elapsed: 00:00:00.44
# Mc/sec: 6018.42
//
Query:       EEA21731.1  [L=80]
Description: hypothetical protein PMAA_055280 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.19    9.8   0.0       0.19    9.8   0.0    1.0  1  Patched   Patched family


Domain annotation for each model (and alignments):
>> Patched  Patched family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0   1.1e-05      0.19     276     307 ..       2      34 ..       1      61 [. 0.83

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 1.1e-05
     Patched 276 lwlGfrfns.ivtvtPFLvLaiGvDdmflmvaa 307
                  ++G r+ + i+t++P  vL i +Dd+ lmv+ 
  EEA21731.1   2 AAIGQRYLQgITTISPQNVLNIPIDDLLLMVHM 34 
                 67888986559********************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (80 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       244  (0.0136092); expected 358.6 (0.02)
Passed bias filter:                      237  (0.0132188); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.24s 00:00:00.62 Elapsed: 00:00:00.41
# Mc/sec: 581.56
//
Query:       EEA21732.1  [L=503]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.5e-164  548.4   1.1   7.1e-164  546.2   1.1    1.8  1  DUF5427   Family of unknown function (DUF5427)
     0.0035   17.5   1.9     0.0099   16.1   0.9    2.1  2  Flu_M1_C  Influenza Matrix protein (M1) C-terminal domain
  ------ inclusion threshold ------
       0.71    9.5   2.9          1    8.9   2.9    1.2  1  SARAF     SOCE-associated regulatory factor of calcium homoeo
        2.2    7.6  11.5        3.5    6.9  11.5    1.2  1  CDC27     DNA polymerase subunit Cdc27


Domain annotation for each model (and alignments):
>> DUF5427  Family of unknown function (DUF5427)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  546.2   1.1  1.6e-167  7.1e-164       2     465 .]      15     473 ..      14     473 .. 0.86

  Alignments for each domain:
  == domain 1  score: 546.2 bits;  conditional E-value: 1.6e-167
     DUF5427   2 efleslpedktvk.......kkkkkkktkkkkkakkkdeediLaeLeeLakkesrpaTPrvksnkskkaspkkkksaeepakeekkkeeessedkrksv 93 
                 +++++l+ d+t k        +++++++ ++++a ++ e+d LaeLe+La+  +rp+TPr++ +    ++pk ++  ++++k++++ +++  e      
  EEA21732.1  15 AQFDDLGIDTTGKsseptpaPPSTTSTKPASTEAPTAIEKDPLAELENLAS--QRPSTPRLSAE---ARRPKPSSGRTSEEKPATQPRAAVVE------ 102
                 7899999888555577777544445555555555555567*********99..7*******988...33344333333333222221112211...... PP

     DUF5427  94 estrsleasetpseeeseeqeaekkeeeeeeaeeeeadpiasgsgWWgsil....atasaavkqaeaavkeiqtneeAkkwaeqvrgnvgalrglgdel 188
                        +++ p++ ++             + ++++++p++sg+gWWg++l    ata+aa+kqaeaavkeiq+neeA+kwaeqvrgnvgalrglg+el
  EEA21732.1 103 -------DEQLPEKVTP-------------APAATNEEPKSSGGGWWGGFLstatATATAAMKQAEAAVKEIQKNEEAQKWAEQVRGNVGALRGLGGEL 181
                 .......1222222222.............2223456899*********998888899***************************************** PP

     DUF5427 189 rtralptltellktlappisshEvLqIhithDlvnypsLdplvyekFsrvmsqVeGgdllvvqrgqesterrssee.sskssagwrdgpwwrq...dsk 283
                 rt alpt+t++++tlappisshE+LqIhithDl++ypsLdp+++++F+rvmsqVeGgdllv+qrgqes+ rr ++   ++s +gwrdgpwwr+   +++
  EEA21732.1 182 RTLALPTFTSIIHTLAPPISSHERLQIHITHDLSGYPSLDPIIHSVFARVMSQVEGGDLLVIQRGQESSPRRGTDFgFQSSITGWRDGPWWRTitpGTP 280
                 **********************************************************************998888888999***********99999* PP

     DUF5427 284 rdLnlvkGlvegeKLaranaesyakeyfkarggleeaakrakeelsesnpvrssdiFlaiqaisvkskk........aaeekekeesevvdenee.des 373
                 r++ +v G+v g+KLara+ae+ya+e++++rgg+eeaak+a+e lsesnpvrssdiFl+iqais++ +k        a++++ ++  +vv++ +e +e+
  EEA21732.1 281 RSIAAVPGVVPGTKLARASAEAYATEFYSSRGGIEEAAKQATEILSESNPVRSSDIFLSIQAISQTMPKdlfqagptAEKATPEAAGGVVEPADEgEEE 379
                 ************************************************************************9666333344444559****9999*** PP

     DUF5427 374 vsFaivlkDivhditfitvSQsfPlkWieWLdaekpktseskeee..elpeeieeiiesggvdPreWVaeWieegLsLavGvvAqrYVakRMGv 465
                 + Fa++l+D++h+i+f+t+SQ++P kWi+WLda+ p++++++ +   ++pe+i++iiesggvdPreWV+eW+ee+L+L+ GvvAqrYVa+RMGv
  EEA21732.1 380 ILFAVYLHDPIHGIAFSTISQAVPRKWIDWLDASVPASDDQEGDMrtKIPEAIQDIIESGGVDPREWVSEWLEEALNLSTGVVAQRYVARRMGV 473
                 **********************************9999887766678**********************************************8 PP

>> Flu_M1_C  Influenza Matrix protein (M1) C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.9   2.2e-06    0.0099      28      65 ..     139     180 ..     133     185 .. 0.70
   2 ?   -0.9   0.0      0.43   1.9e+03      12      50 ..     285     326 ..     281     352 .. 0.68

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 2.2e-06
                 XX.XXXXXXXX...XXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
    Flu_M1_C  28 ta.kameqmag...ssekaeevqklaeelrqnvqvlrslGas 65 
                 ta  am+q  +     +k ee+qk ae++r nv++lr lG +
  EEA21732.1 139 TAtAAMKQAEAavkEIQKNEEAQKWAEQVRGNVGALRGLGGE 180
                 3312455543301145799********************975 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.43
                 XXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXX CS
    Flu_M1_C  12 svPlvrrenrmvlasttakameqma...gssekaeevqklae 50 
                 +vP+v    ++  as+ a a e  +   g  e a+++ ++ +
  EEA21732.1 285 AVPGVVPGTKLARASAEAYATEFYSsrgGIEEAAKQATEILS 326
                 688888888999999988888765411044444445555444 PP

>> SARAF  SOCE-associated regulatory factor of calcium homoeostasis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   2.9   0.00023         1     211     290 ..      88     168 ..      29     177 .. 0.72

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00023
       SARAF 211 seeeqddpPppysltksqkpsssses.sqqgeqeeswrpGFWtGlatGaaaGYlagrrraqneeteeeekeksssWgssse 290
                 see+ ++ P+   ++++q p++ + + + ++e+ +s  +G+W G+ + a a+  a+ ++a+   +e +++e++++W ++ +
  EEA21732.1  88 SEEKPATQPRAAVVEDEQLPEKVTPApAATNEEPKSSGGGWWGGFLSTATATATAAMKQAEAAVKEIQKNEEAQKWAEQVR 168
                 222224444444556666666665556555556666669*****************9999999999999999****98765 PP

>> CDC27  DNA polymerase subunit Cdc27
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9  11.5   0.00079       3.5     136     252 ..      26     167 ..      18     171 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.00079
       CDC27 136 grpplaapaseakektangkkpka.........................akekaaketssakseskkksaekskdaskettkekaekaasskaaslkkk 209
                 g+++ ++pa+++ + t+++ ++++                         a     k++s   se k++ ++ ++ ++ e+ +ek + a+   +++ k +
  EEA21732.1  26 GKSSEPTPAPPSTTSTKPASTEAPtaiekdplaelenlasqrpstprlsAEARRPKPSSGRTSEEKPATQPRAAVVEDEQLPEKVTPAPAATNEEPKSS 124
                 445555555566666666555544569999999****99999999886533333344444455667777778888899999*********999999*** PP

       CDC27 210 asaksnimksffkakpaekkkkteakeqkveeeseeekekedk 252
                 +  +++ + s + a + ++ k++ea  ++++++ e++k +e++
  EEA21732.1 125 GGGWWGGFLSTATATATAAMKQAEAAVKEIQKNEEAQKWAEQV 167
                 ****************999999999999999998888877776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (503 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       777  (0.0433376); expected 358.6 (0.02)
Passed bias filter:                      509  (0.0283898); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.65u 0.30s 00:00:00.95 Elapsed: 00:00:00.46
# Mc/sec: 3268.31
//
Query:       EEA21733.1  [L=342]
Description: acid phosphatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.1e-53  179.1   0.0    2.8e-52  177.4   0.0    1.8  1  SurE             Survival protein SurE
  ------ inclusion threshold ------
      0.071   13.6   0.5       0.25   11.8   0.0    2.0  2  Glyco_trans_4_4  Glycosyl transferase 4-like domain
       0.13   12.3   5.3       0.21   11.5   5.3    1.3  1  DUF3439          Domain of unknown function (DUF3439)
        1.2    7.3   5.5        1.6    6.9   5.5    1.1  1  SSP160           Special lobe-specific silk protein SSP160
        1.4    6.9   2.8        2.1    6.2   2.8    1.2  1  Dicty_REP        Dictyostelium (Slime Mold) REP protein


Domain annotation for each model (and alignments):
>> SurE  Survival protein SurE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  177.4   0.0   7.7e-56   2.8e-52       1     194 [.       3     259 ..       3     260 .. 0.84

  Alignments for each domain:
  == domain 1  score: 177.4 bits;  conditional E-value: 7.7e-56
                 EEEE-SS-TT....-HHHHHHHHHHTTTTSEEEEEEESSS-TTCTTS--SSSEE......................EEEEEECS............... CS
        SurE   1 iLltNDDGie....apgiralvealaaaghevvvvaPdserSgigkaltleepl......................rveseeee............... 58 
                 iL++NDDG++    +p++r l++al++agh+v+v++P+++rS+igka+ +  +l                             +               
  EEA21733.1   3 ILVVNDDGPPskklSPYVRPLADALKDAGHRVSVAIPAASRSWIGKAHIIGASLtatyvhpdsfredgtwidenekD------Dtptaatttttttttt 95 
                 8*********999999********************************87799955656666555555555555550......0555555555566667 PP

                 ............................TTTCEEEE..SS-HHHHHHHHHHTTTTTS.S.SEEEEEEEES---GGGG.GG-HHHHHHHHHHHTTSEEEE CS
        SurE  59 ............................eeeeeyav..sGtPadcvklaleellkekkp.dlVvSGiNhGaNlgtdv.lySGTvgAaleaalegipaiA 125
                                             +ee+ +av  +GtPa+c++l+l el++++ p dlV+SG+NhG+N++t + l+SGTvg+aleaa++g ++iA
  EEA21733.1  96 tmtnghlpptpaassehlnvstpddqneNEEDYWAVisNGTPASCAQLGLYELFPNRGPiDLVISGPNHGRNASTIYnLSSGTVGGALEAATCGKRGIA 194
                 77778888888888888888888888889999999999*****************99777*************************************** PP

                 EEEESSSSS-SSS---HHHHHHHHHHHHTTETTS-...SS-EEEEEEESS.GCG-SEEEE-B--CCSCE CS
        SurE 126 vSlaskkeeekkeedtfeaaakvaaklveklieklllekvellnvNvPeleeeeikgvkvtrlgrrrys 194
                 +S++sk  +e ++  t++aaa++ ++++e+l  + ++e+vel+n+NvP  e+ e + v++tr +r++++
  EEA21733.1 195 LSFGSK--DE-QPPATIAAAARLSTRVIEHL-WRNWDERVELYNLNVPMREDVESRPVRYTRALRNEWT 259
                 ****86..33.44566999888888888776.45559***********99999999999*******997 PP

>> Glyco_trans_4_4  Glycosyl transferase 4-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0     7e-05      0.25       5      31 ..      18      44 ..      16      92 .. 0.81
   2 ?   -1.1   0.2      0.63   2.3e+03      53      74 ..     204     226 ..     180     255 .. 0.58

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 7e-05
  Glyco_trans_4_4  5 ryvaelaraLaarGheVtvltpapapg 31
                      yv+ la aL ++Gh+V v +pa+ ++
       EEA21733.1 18 PYVRPLADALKDAGHRVSVAIPAASRS 44
                     69*******************998876 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.63
  Glyco_trans_4_4  53 pladlaalralrrll.rqrrerp 74 
                      p+a+ aa+++l   + ++ ++++
       EEA21733.1 204 PPATIAAAARLSTRViEHLWRNW 226
                      44444444444333322222222 PP

>> DUF3439  Domain of unknown function (DUF3439)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   5.3   5.9e-05      0.21      47      72 ..      85     109 ..      42     121 .. 0.64

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 5.9e-05
     DUF3439  47 ttttttttttttmpttttlptttkms 72 
                 +tttttttttttm t   lp t   s
  EEA21733.1  85 ATTTTTTTTTTTM-TNGHLPPTPAAS 109
                 3444444444444.666777765555 PP

>> SSP160  Special lobe-specific silk protein SSP160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   5.5   0.00043       1.6     671     697 ..      79     105 ..      30     115 .. 0.63

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.00043
      SSP160 671 gsvpdeattttssttttttttttaapt 697
                    p +atttt++ttttt t     pt
  EEA21733.1  79 DDTPTAATTTTTTTTTTTMTNGHLPPT 105
                 344666666655555555555444444 PP

>> Dicty_REP  Dictyostelium (Slime Mold) REP protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   2.8   0.00058       2.1     245     270 ..      75     100 ..      63     131 .. 0.66

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.00058
   Dicty_REP 245 ensqpskeknkttttttttttttsqa 270
                 en ++++ +++ttttttttttt ++ 
  EEA21733.1  75 ENEKDDTPTAATTTTTTTTTTTMTNG 100
                 45666777777777777666666554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       625  (0.0348597); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.48
# Mc/sec: 2146.06
//
Query:       EEA21734.1  [L=801]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
     0.0029   17.7  10.4     0.0054   16.8  10.4    1.4  1  Zn_clus        Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.096   13.4   0.4        0.3   11.8   0.4    1.8  1  WW_FCH_linker  Unstructured linker region between on GAS7 pro


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8  10.4     6e-07    0.0054       3      24 ..     444     464 ..     442     473 .. 0.93

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 6e-07
                 -HHHHHCT---STSSSS-HHHH CS
     Zn_clus   3 CdnCrkkKvKCdakkPaCsnCk 24 
                 C +Cr  K+KCd++ P C  C+
  EEA21734.1 444 CVQCRLNKRKCDGNSP-CDACR 464
                 ****************.****7 PP

>> WW_FCH_linker  Unstructured linker region between on GAS7 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.4   3.4e-05       0.3       4      78 ..     318     398 ..     316     404 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3.4e-05
  WW_FCH_linker   4 pgtPksplrqknslPavnGyhssgs....pvhqlesshvsl..rksstekqspgstsptrkqskettvtincvtfPspdvm 78 
                    p  P+++l+     P+vnG+  s      p   le+ ++++   + +    +p s++ +rk+   + v i+ +  P p ++
     EEA21734.1 318 PVSPEKSLESSPEFPKVNGFMVSEDtsdiPQMSLEQERRNIvgSRHTPSAFQPASVARKRKHRNSSIVNIDQIQQPRPLQI 398
                    67899999999999******9875411114445667666665556666667789999999999999999****99999765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (801 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       605  (0.0337442); expected 358.6 (0.02)
Passed bias filter:                      403  (0.0224776); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.45
# Mc/sec: 5398.65
//
Query:       EEA21735.1  [L=82]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-16   61.2   8.6    1.2e-16   61.2   8.6    1.4  1  DUF2462   Protein of unknown function (DUF2462)


Domain annotation for each model (and alignments):
>> DUF2462  Protein of unknown function (DUF2462)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.2   8.6   6.8e-21   1.2e-16       1      77 []       1      69 [.       1      69 [. 0.91

  Alignments for each domain:
  == domain 1  score: 61.2 bits;  conditional E-value: 6.8e-21
     DUF2462  1 MaQGklKkkkkkksakakkkaknpkkgarviaPKkaklvkqqklkkklsaglnkktEkelasrAgsskLellkggkk 77
                MaQ  lK   k   ak+++++k+ k g+rvi+PKk +l kq+k +kkls+gl +ktE+ la+rAg  +Lell + kk
  EEA21735.1  1 MAQAPLK---K---AKPTTAKKSSKLGPRVITPKKVALAKQRKSMKKLSSGLINKTERSLAERAG--HLELLVNAKK 69
                *******...3...45666667789****************************************..****988775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (82 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       971  (0.0541581); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.27s 00:00:00.68 Elapsed: 00:00:00.45
# Mc/sec: 553.58
//
Query:       EEA21736.1  [L=829]
Description: hypothetical protein PMAA_055330 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.8e-05   22.1   1.2     0.0002   21.0   1.2    1.6  1  Golgin_A5      Golgin subfamily A member 5
  ------ inclusion threshold ------
      0.041   13.9   0.4       0.32   11.0   0.0    2.6  2  FlxA           FlxA-like protein
       0.11   12.6   1.7         32    4.6   0.5    3.5  3  TMF_DNA_bd     TATA element modulatory factor 1 DNA binding
       0.14   12.3   9.2       0.29   11.3   4.3    2.9  3  Tropomyosin_1  Tropomyosin like
       0.58   10.3   4.6        2.8    8.1   4.7    2.0  1  CEP209_CC5     Coiled-coil region of centrosome protein CE290
        1.3    8.7   3.6        1.5    8.5   2.1    2.0  2  SSXRD          SSXRD motif
        3.5    6.9   5.4        6.8    5.9   5.4    1.4  1  DUF4407        Domain of unknown function (DUF4407)
        7.8    6.3   7.8         15    5.4   1.5    2.6  2  BBP1_C         Spindle pole body component BBP1, C-terminal


Domain annotation for each model (and alignments):
>> Golgin_A5  Golgin subfamily A member 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0   1.2   8.8e-08    0.0002      57     191 ..     227     357 ..     190     433 .. 0.80

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 8.8e-08
   Golgin_A5  57 dllreelqklnqqieqlrtelqdleaqqqaeaeslreqlqeleeqleeerkakeeveaelerl.keelryleeelvrskatlqsrikdrekeieklrnq 154
                 +l+  + +++ +q ++ + ++ +l a + ae++ lr++++e e++++   +++  +++++e++ + ++ +le +l    +++ +rik+ e e + + ++
  EEA21736.1 227 QLAAVQNHSSPMQASTTKPQVSKLRALN-AEIKVLRQEIAEWEDKFDVRVHEEVGLRTDVESKlRTKIIFLEGQL----EDYATRIKELECERDLQAQK 320
                 3333344455566677777777877665.9*****************************9865145555555555....58899999999999999999 PP

   Golgin_A5 155 lttkslsssseselesRlkqLtesLiqKQtvlEalst 191
                 l + +   s++  le R+  Lte L q  t +E  s 
  EEA21736.1 321 LRNVESLRSTNRGLERRIDVLTELLAQSPTKIEPRSP 357
                 999999999*********************9997665 PP

>> FlxA  FlxA-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00014      0.32       4      68 ..     206     267 ..     203     274 .. 0.85
   2 ?   -1.1   0.1      0.86   1.9e+03      17      45 ..     291     319 ..     280     347 .. 0.60

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00014
        FlxA   4 ssasssssssgsasqiasLqkQiknlqkqLkelsesdeltkeekkkqqqliqaQIqqlqaQIaql 68 
                 s++ + + ++ ++ +i+ L+ Q++ +q+  + +++s+++++     +   + a+I++l+++Ia  
  EEA21736.1 206 SNSRDRADNYATERYIEHLEAQLAAVQNHSSPMQASTTKPQV---SKLRALNAEIKVLRQEIAEW 267
                 56677888999999***************9999999555555...88889************975 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.86
        FlxA  17 sqiasLqkQiknlqkqLkelsesdeltke 45 
                 ++i  L+ Q++++   +kel  + +l ++
  EEA21736.1 291 TKIIFLEGQLEDYATRIKELECERDLQAQ 319
                 44555555666666666665554333333 PP

>> TMF_DNA_bd  TATA element modulatory factor 1 DNA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0     0.031        71      28      47 ..     250     269 ..     247     273 .. 0.77
   2 ?    2.4   0.2     0.069   1.5e+02      37      72 ..     288     323 ..     284     325 .. 0.84
   3 ?    4.6   0.5     0.014        32      25      64 ..     314     353 ..     304     360 .. 0.81

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.031
  TMF_DNA_bd  28 elklnntikkLrkknkelek 47 
                  ++ln+ ik Lr++++e e 
  EEA21736.1 250 LRALNAEIKVLRQEIAEWED 269
                 56788999999999998775 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.069
  TMF_DNA_bd  37 kLrkknkelekeikelkkkleklekeleeleerlke 72 
                 kLr k+  le +++++  ++++le e + + ++l++
  EEA21736.1 288 KLRTKIIFLEGQLEDYATRIKELECERDLQAQKLRN 323
                 899999999999999999999999888888877765 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.014
  TMF_DNA_bd  25 skkelklnntikkLrkknkelekeikelkkkleklekele 64 
                 ++ + +    + +Lr++n+ le  i+ l++ l+++  ++e
  EEA21736.1 314 RDLQAQKLRNVESLRSTNRGLERRIDVLTELLAQSPTKIE 353
                 5556666677999*****************9999988887 PP

>> Tropomyosin_1  Tropomyosin like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   1.0      0.03        67      69     132 ..     208     272 ..     177     279 .. 0.71
   2 ?   11.3   4.3   0.00013      0.29       8      95 ..     263     351 ..     249     360 .. 0.66
   3 ?   -4.3   0.0         8   1.8e+04      85      94 ..     570     579 ..     564     590 .. 0.68

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.03
  Tropomyosin_1  69 ekkktnnealtrkiqlLEeeleesd...kkLkettekLretdvkaeelERkvkaLeqerdewekkye 132
                    ++++++n a +r i+ LE +l   +   + ++  t+k + + ++a + E  +k+L qe +ewe+k++
     EEA21736.1 208 SRDRADNYATERYIEHLEAQLAAVQnhsSPMQASTTKPQVSKLRALNAE--IKVLRQEIAEWEDKFD 272
                    3445555577888888888886544111457777788777777776555..7778999999999987 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00013
  Tropomyosin_1   8 eaeeaqekaeeleekvKeleqenlekeqeiksLtkknqqleeevekleeklkeakekaeesekkktnne.......altrkiqlLEeeleesdkk 95 
                    e  e+ +k      +v+  e+  l+ + e ++L +k+  le ++e + +++ke + + + +++k  n e        l+r+i++L e l +s +k
     EEA21736.1 263 EIAEWEDKF-----DVRVHEEVGLRTDVE-SKLRTKIIFLEGQLEDYATRIKELECERDLQAQKLRNVEslrstnrGLERRIDVLTELLAQSPTK 351
                    333333332.....245555555555555.5699*******************999999999999999955555556666666666666665554 PP

  == domain 3  score: -4.3 bits;  conditional E-value: 8
  Tropomyosin_1  85 LEeeleesdk 94 
                    L  elee+++
     EEA21736.1 570 LDSELEEAER 579
                    4555555554 PP

>> CEP209_CC5  Coiled-coil region of centrosome protein CE290
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   4.7    0.0013       2.8      41     117 ..     251     327 ..     217     336 .. 0.74

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0013
  CEP209_CC5  41 eelistlkdakgaqkvleWhkkieelrlqelklkrel.tkqkeeikylknlieeqertisklEeei.vqlnkvheerql 117
                   l + +k   ++q+++eW  k +    +e+ l+  + +k +++i +l+++ e +   i++lE e  +q +k+++ + l
  EEA21736.1 251 RALNAEIK--VLRQEIAEWEDKFDVRVHEEVGLRTDVeSKLRTKIIFLEGQLEDYATRIKELECERdLQAQKLRNVESL 327
                 44555554..46799********9988889888888735679*********************7742666666555555 PP

>> SSXRD  SSXRD motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.0       4.6     1e+04      22      27 ..     122     127 ..     118     127 .. 0.86
   2 ?    8.5   2.1   0.00067       1.5      14      30 ..     532     548 ..     532     549 .. 0.91

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 4.6
                 XXXXXX CS
       SSXRD  22 eEiSDP 27 
                 +Ei+D+
  EEA21736.1 122 QEIHDS 127
                 8***95 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00067
                 XXXXXXXXXXXXXXC-T CS
       SSXRD  14 RERKlvvYeEiSDPeeD 30 
                 R R ++ Ye +S+Pe+D
  EEA21736.1 532 RTRHYQEYEDMSEPEDD 548
                 7788999*********9 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   5.4     0.003       6.8     131     259 ..     203     350 ..     175     354 .. 0.68

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.003
     DUF4407 131 ltaelaeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaakekkaqldaaqaelaelkakld...................... 207
                      ++ +a++ a ++ i+ +ea+l+a +++         +     ++ +    ++ +a+++ +++e+ae+++k d                      
  EEA21736.1 203 RPRSNSRDRADNYATERYIEHLEAQLAAVQNHSSPMQAS--T-----TKPQVSKLRALNAEIKVLRQEIAEWEDKFDvrvheevglrtdvesklrtkii 294
                 333334444444455555555555555555555522222..2.....223457789999999999999999999999********************** PP

     DUF4407 208 ....atarlaalraelaeleaerakeraasqaaaaaddGllarlealdrltkedat 259
                     + ++ a++ +el+  ++ +a++ ++ ++ ++ ++Gl  r++ l +l ++++t
  EEA21736.1 295 flegQLEDYATRIKELECERDLQAQKLRNVESLRSTNRGLERRIDVLTELLAQSPT 350
                 *666666666666666666666666666777788999*************998875 PP

>> BBP1_C  Spindle pole body component BBP1, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   1.5    0.0066        15     108     172 ..     189     253 ..     179     274 .. 0.67
   2 ?    3.8   1.9     0.019        43      86     160 ..     253     327 ..     246     344 .. 0.71

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.0066
      BBP1_C 108 ikkleeklldlelrnkeleekreidkikYesrikdLerqllereneikdtssssnafstseyrkk 172
                 ++++++ l+ l+ +    +++   d+ + e+ i+ Le+ql + +n+ ++ ++s  + + s+ r  
  EEA21736.1 189 QQNRSSPLSTLNTNRPRSNSRDRADNYATERYIEHLEAQLAAVQNHSSPMQASTTKPQVSKLRAL 253
                 4555556666666666677778888999999************9998866666666655555544 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.019
      BBP1_C  86 lqskianlekqlvdqaiekdreikkleeklldlelrnkeleekreidkikYesrikdLerqllereneikdtsss 160
                 l+++i+ l++++ + + + d + ++    + d+e + +      e +   Y +rik+Le +  ++ ++ ++++s 
  EEA21736.1 253 LNAEIKVLRQEIAEWEDKFDVRVHEEVGLRTDVESKLRTKIIFLEGQLEDYATRIKELECERDLQAQKLRNVESL 327
                 67778888888877777777777776666666655554444457777889*********7777776666666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (829 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1062  (0.0592336); expected 358.6 (0.02)
Passed bias filter:                      614  (0.0342462); expected 358.6 (0.02)
Passed Vit filter:                        77  (0.00429472); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.74u 0.30s 00:00:01.04 Elapsed: 00:00:00.45
# Mc/sec: 5591.56
//
Query:       EEA21737.1  [L=254]
Description: GPI anchored serine-threonine rich protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-22   80.6   0.3    1.1e-22   80.6   0.3    2.3  2  GPI-anchored  Ser-Thr-rich glycosyl-phosphatidyl-inositol-anc


Domain annotation for each model (and alignments):
>> GPI-anchored  Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.6   0.3   5.9e-27   1.1e-22       2      93 .]      39     129 ..      38     129 .. 0.93
   2 ?   -0.9   1.5      0.16   2.9e+03      16      23 ..     158     165 ..     142     229 .. 0.58

  Alignments for each domain:
  == domain 1  score: 80.6 bits;  conditional E-value: 5.9e-27
  GPI-anchored   2 sPssgevvtagkpvtitWkdsgtdpgtvtlvLcagssnnlksvktiasgiknsdgsytwtv...paslesggaYflqivsesnegiynySdrFti 93 
                   +P++ + vt ++p++itW++  t+pg+v lvLc+g+s+n++++ tia++++ns g++twt+   ++s  s+g+Y++ ++++++e +y+y+++F++
    EEA21737.1  39 TPDTTHPVTLDAPYQITWDP--TTPGPVALVLCKGPSTNCEPILTIADQVPNS-GEFTWTPsglEPSATSAGGYGIMLIDYATE-AYQYTTQFGV 129
                   799*****************..9*****************************9.*******555557777779**********7.********87 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.16
  GPI-anchored  16 titWkdsg 23 
                   t+t  +s+
    EEA21737.1 158 TVTILPSS 165
                   33333222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (254 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       546  (0.0304535); expected 358.6 (0.02)
Passed bias filter:                      286  (0.0159518); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 1814.71
//
Query:       EEA21738.1  [L=79]
Description: hypothetical protein PMAA_055350 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-19   69.0   0.2    4.6e-19   68.8   0.2    1.0  1  RTA1      RTA1 like protein


Domain annotation for each model (and alignments):
>> RTA1  RTA1 like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.8   0.2   2.6e-23   4.6e-19      39      98 ..       1      60 [.       1      71 [. 0.92

  Alignments for each domain:
  == domain 1  score: 68.8 bits;  conditional E-value: 2.6e-23
        RTA1 39 laPafiaaaiYmllgrlilllgeelsllrpklytkiFvvlDvvslllqaaGGglaasass 98
                ++Paf++a++Y++l+r+++++ge++s+++p +y  iF+++D++sl lq++GG l   ++s
  EEA21738.1  1 MGPAFYSAGLYLCLARIVIVYGEKISRIQPAWYIRIFITCDIISLSLQGGGGELFVYDTS 60
                59**************************************************99877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (79 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       243  (0.0135535); expected 358.6 (0.02)
Passed bias filter:                      215  (0.0119917); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.34u 0.24s 00:00:00.58 Elapsed: 00:00:00.37
# Mc/sec: 632.01
//
Query:       EEA21739.1  [L=889]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.2e-12   44.6   0.5    1.6e-11   43.8   0.5    1.3  1  Fungal_trans  Fungal specific transcription factor domain
    1.3e-06   28.4  11.1    2.4e-06   27.5  11.1    1.5  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
       0.18   12.4   0.5       0.51   11.0   0.0    2.0  2  DUF4690       Small Novel Rich in Cartilage


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.8   0.5   2.6e-15   1.6e-11       1     257 [.     267     517 ..     267     527 .. 0.75

  Alignments for each domain:
  == domain 1  score: 43.8 bits;  conditional E-value: 2.6e-15
  Fungal_trans   1 ldrffsnfhpqfpilhkpsflpkt.....ssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslw 92 
                   l++++  +hp    lh+psf   +       +n  + + +  + +la+l  ++ +++++++   s +t+e  + +++ ++  +l+ +++ ++++ ++
    EEA21739.1 267 LEHYWLSVHPVARTLHRPSFAQRYetlweLIDNGANVPASLGAIVLAVLLAASVSVSKDENAALSHSTQET-MRLKQGVEV-ALSKANLLVSNK-ME 360
                   689**********************9887444444444444555577777777777777777667777766.666666664.455577889999.** PP

  Fungal_trans  93 ilqsLlllelyektssd.ralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcd 188
                   +lq++  +    +++++  ++h  ++g+avrla  +g hr+p  ++       + +e + rr +w+ + ylD +++ + G  p+   +  ++ LP +
    EEA21739.1 361 TLQAFITYL-LPMCLDEiSRAHSALVGLAVRLAECMGYHRDPTEYS------FSTAECQVRRLIWYQICYLDWRTSEVQGPRPFVQPNGYSTKLPLE 450
                   ***654333.23333345789999********************99......77777999***********************99999999999954 PP

  Fungal_trans 189 dddlwesddaseetlvetklsneeksrkiasfllaLkkilsk.iagsllsiekqlqqrdlq.....seklswvee 257
                         s++ s++  +    sn+e+++ ++  ++++ ++  + +++++l i+k+ ++++l+     s+ ++  ++
    EEA21739.1 451 I-----SSSSSQFSSPT---SNPESGPRWSDMIFSVIRFECQeMHRTCLVIRKKVDLKKLSitaaiSKLERFSKD 517
                   4.....45555555555...5567888888888888888755599999999999999999866665444444445 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.5  11.1   4.1e-10   2.4e-06       1      36 [.      47      81 ..      47      85 .. 0.89

  Alignments for each domain:
  == domain 1  score: 27.5 bits;  conditional E-value: 4.1e-10
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfyses 36
                ++C +Cr++K KCd++   C nC++ n +C ++s s
  EEA21739.1 47 TSCLECRRRKLKCDKQEV-CMNCRTQNRQCIYISSS 81
                69************9988.************77765 PP

>> DUF4690  Small Novel Rich in Cartilage
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.1   0.1         3   1.8e+04      19      40 ..      12      35 ..       7      38 .. 0.64
   2 ?   11.0   0.0   8.5e-05      0.51      59      83 ..     298     322 ..     278     324 .. 0.84

  Alignments for each domain:
  == domain 1  score: -4.1 bits;  conditional E-value: 3
     DUF4690 19 sGeg.ple.sttkeresdltdlpa 40
                sG + + +  t+++  s +td p+
  EEA21739.1 12 SGRDsSPDtITSSNTGSRVTDKPV 35
                554414554677777888888776 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 8.5e-05
     DUF4690  59 eegslGPGaiaaiviaalLgasvll 83 
                 ++g+  P +++aiv+a+lL+asv +
  EEA21739.1 298 DNGANVPASLGAIVLAVLLAASVSV 322
                 3567789***************965 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (889 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       696  (0.0388198); expected 358.6 (0.02)
Passed bias filter:                      426  (0.0237604); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.67u 0.31s 00:00:00.98 Elapsed: 00:00:00.46
# Mc/sec: 5870.44
//
Query:       EEA21740.1  [L=594]
Description: multicopper oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.6e-43  147.5   4.7    1.6e-42  144.3   1.1    3.0  3  Cu-oxidase_3  Multicopper oxidase
    8.4e-32  110.5   0.0    1.4e-30  106.5   0.0    2.6  2  Cu-oxidase    Multicopper oxidase
    5.5e-31  107.1   7.0    3.4e-28   98.1   0.7    3.4  3  Cu-oxidase_2  Multicopper oxidase


Domain annotation for each model (and alignments):
>> Cu-oxidase_3  Multicopper oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  144.3   1.1   2.6e-46   1.6e-42       7     118 ..      82     195 ..      77     196 .. 0.94
   2 ?    3.2   0.0     0.014        82      29      56 ..     457     484 ..     445     507 .. 0.87
   3 ?   -2.4   0.0      0.75   4.5e+03      85     109 ..     529     552 ..     522     555 .. 0.78

  Alignments for each domain:
  == domain 1  score: 144.3 bits;  conditional E-value: 2.6e-46
                   EECTTEESEEEEEECTSSBS-EEEEETT-EEEEEEEE-S...SS-B-EEEET--S-GG.....GSCSGGG-B-TT-EEEEEEE--S-SEEEEEEE-- CS
  Cu-oxidase_3   7 vsplggterevitvNgqfpgptievregdtvvvnvtNkl...dentsihwhGlqqrktswmDGvpgvtqcpiqpgesftyrftvkqqagtlwYhshl 100
                   + +++g++++ + +Ngqfpgptie+++gdt++v+vtN++    e+t++hwhGl qr+t+w DGvp ++qcpi+p++sfty+ft++q +gt wYhsh+
    EEA21740.1  82 WMMADGVNKTGLYINGQFPGPTIEANWGDTIQVTVTNHIkdsAEGTAMHWHGLLQRETPWFDGVPSLSQCPIAPEKSFTYSFTADQ-YGTSWYHSHY 177
                   445666779******************************887789*****************************************.********** PP

                   TTHHHTT-EEEEEEE-HH CS
  Cu-oxidase_3 101 slqqaaGlaGaiiiedke 118
                   s+q+a+G +Ga+ii+ +e
    EEA21740.1 178 SAQYADGTFGAMIIYGPE 195
                   **************9875 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.014
                   EEEETT-EEEEEEEE-SSS-B-EEEET- CS
  Cu-oxidase_3  29 ievregdtvvvnvtNkldentsihwhGl 56 
                   +++ +++t+++ v+N ++    +h+hG 
    EEA21740.1 457 LDFGKNETIRLYVRNFIPLAHPMHLHGH 484
                   667899***********99999**9996 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 0.75
                   EE--S-SEEEEEEE--TTHHHTT-E CS
  Cu-oxidase_3  85 ftvkqqagtlwYhshlslqqaaGla 109
                   +++++  g   +h h++++  +Gl+
    EEA21740.1 529 YKADN-PGIWPFHCHVAWHVSDGLY 552
                   55566.677779******9889987 PP

>> Cu-oxidase  Multicopper oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.5   0.0   2.4e-34   1.4e-30       4     157 ..     205     360 ..     202     362 .. 0.90
   2 ?    0.6   0.0     0.088   5.3e+02      61     105 ..     456     504 ..     435     513 .. 0.76

  Alignments for each domain:
  == domain 1  score: 106.5 bits;  conditional E-value: 2.4e-34
                 EEEEEEETCBCTTSCBC.HSSCHCHHHHHTT--SEEEETTBSS...........CTTTTSGGGEEEEETTEEEEEEEESSS-BEEEEETSB-EEEEEET CS
  Cu-oxidase   4 vitlsDwyhkdakelekellasgkapadtppvpdavlingkggfnatlad....kdgaslatltvepgktyrlriinvsaddslnfsIeGHkltVvevD 98 
                 +++l+D++h+    l++++  s++      p +d+ lingk++f+++la+    + +a l ++++e+gk +rlr+in++a+   +f+I+ H++tV+++D
  EEA21740.1 205 PVLLTDYFHTRYYLLVQRYTGSQD-----VPNSDNNLINGKMNFDCSLAEgtecMPNAGLSKFKFESGKIHRLRLINAGAEALQKFTIDEHEMTVIATD 298
                 789***********9998877755.....456*****************96555588899*************************************** PP

                 CETTSEEEESCEEE-TTEEEEEEEEE-S.S..SEEEEEEEEGSSSCHHHHTTSEEEEEEEES CS
  Cu-oxidase  99 gvyvepvevdsldIavGqrysvlvtanq.a..pgnYwivasgrsnlieafengtaaailrys 157
                 +++++p++++ + ++vGqr +vlv+ ++ +  +++Yw++  +  +++++ ++  a+a + y+
  EEA21740.1 299 FTPIKPYKTKVVTLGVGQRADVLVEGKDcSdpQKAYWMRSDIPAGTCSHANQSHALAAIYYD 360
                 **************************665356*********888999999999999998887 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.088
                 GGEEEEETTEEEEEEEESSS-BEEEEETSB-EEEEEE.....TCETTSEE CS
  Cu-oxidase  61 tltvepgktyrlriinvsaddslnfsIeGHkltVvev.....Dgvyvepv 105
                 +l++ +++t+rl++ n  +  ++++ ++GH++ + +      Dg+ + p+
  EEA21740.1 456 VLDFGKNETIRLYVRNF-IPLAHPMHLHGHNFWILAQgkgdwDGTITRPA 504
                 56677777777777776.56689999999999988877777777777765 PP

>> Cu-oxidase_2  Multicopper oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.2   1.0   0.00016      0.96      32     127 ..     101     185 ..      72     195 .. 0.74
   2 ?   -2.5   0.0      0.64   3.8e+03      34      87 ..     261     304 ..     233     325 .. 0.60
   3 !   98.1   0.7   5.6e-32   3.4e-28      12     134 ..     441     558 ..     424     561 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00016
                   SEEEEEETTEEEEEEEEE-SSS...-EEEEESS-EEEEEEEEECCCCCCTCCSSGCCGSSCBSEEEE-TTEEEEEEEES.S-EEEEEEESSH.HHHH CS
  Cu-oxidase_2  32 tnvitlpkgevveiviqnntkl...pHPfHlHGhdfqvlgrgpgndpeedpksynlenpvrrdtvqvppggwvairfkadnpGvwllHCHil.wHld 124
                    ++i+++ g++++++++n+ k       +H+HG     l+r++            ++  ++     + p++ +++ f+ad+ G   +H+H   +++d
    EEA21740.1 101 GPTIEANWGDTIQVTVTNHIKDsaeGTAMHWHGL----LQRETPW----------FDGVPSLSQCPIAPEKSFTYSFTADQYGTSWYHSHYSaQYAD 183
                   67888999999*******8888766689****97....7666666..........57777788899999***************99****9945554 PP

                   TT- CS
  Cu-oxidase_2 125 qGm 127
                      
    EEA21740.1 184 G-T 185
                   4.3 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.64
                   EEEEETTEEEEEEEEE-SSS.-EEEEESS-EEEEEEEEECCCCCCTCCSSGCCGS CS
  Cu-oxidase_2  34 vitlpkgevveiviqnntkl.pHPfHlHGhdfqvlgrgpgndpeedpksynlenp 87 
                    ++++ g++ ++ + n +    + f ++ h++ v++++  +            +p
    EEA21740.1 261 KFKFESGKIHRLRLINAGAEaLQKFTIDEHEMTVIATDFTP-----------IKP 304
                   55555566666666665555556666667777777777666...........222 PP

  == domain 3  score: 98.1 bits;  conditional E-value: 5.6e-32
                   CEEEEEEEEEEEETC.CTTTSSEEEEEETTEEEEEEEEE-SSS-EEEEESS-EEEEEEEEECCCCCCTCCSSGCCGSSCBSEEEE-T.....TEEEE CS
  Cu-oxidase_2  12 ltsgneeaseitnge.efsentnvitlpkgevveiviqnntklpHPfHlHGhdfqvlgrgpgndpeedpksynlenpvrrdtvqvpp.....ggwva 102
                   +++g        n + +++++ nv+++ k+e++++++ n  +l HP+HlHGh+f++l++g+g+++ + ++     np+ rd+  v+       ++++
    EEA21740.1 441 AKQG--------NTSyPYDPQWNVLDFGKNETIRLYVRNFIPLAHPMHLHGHNFWILAQGKGDWDGTITRP---ANPQMRDVQIVEMgypyePSYIV 526
                   3322........4444899********************************************76665555...899*****99966555669**** PP

                   EEEES.S-EEEEEEESSHHHHHTT-EEEEEEE CS
  Cu-oxidase_2 103 irfkadnpGvwllHCHilwHldqGmalqfvvr 134
                   i++kadnpG w +HCH++wH++ G++++++++
    EEA21740.1 527 IEYKADNPGIWPFHCHVAWHVSDGLYINLMEN 558
                   ****************************9997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (594 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       337  (0.0187964); expected 358.6 (0.02)
Passed bias filter:                      299  (0.0166769); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.49
# Mc/sec: 3682.01
//
Query:       EEA21741.1  [L=201]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
      6e-08   32.5   0.2      8e-08   32.1   0.2    1.2  1  LOR        LURP-one-related
  ------ inclusion threshold ------
      0.023   14.9   0.1       0.26   11.5   0.0    2.1  2  CdAMP_rec  Cyclic-di-AMP receptor
       0.12   12.3   0.0        0.2   11.6   0.0    1.3  1  MOSC_N     MOSC N-terminal beta barrel domain


Domain annotation for each model (and alignments):
>> LOR  LURP-one-related
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.1   0.2   1.3e-11     8e-08      18     187 .]      26     191 ..      16     191 .. 0.76

  Alignments for each domain:
  == domain 1  score: 32.1 bits;  conditional E-value: 1.3e-11
                 EE----------EEEEETTS-EEEEEE-..SCTTBTTEEEEE-TTS-EEEEEE-.-------EEEEEETT---GGGEEEEEE----------EEEEET. CS
         LOR  18 vwrkslvfnkdgftvyDskGnlvFrVdn.akafslsdelvLmDssGkvLltirr.KklslhdrWevyrgesterkdpvftvkrssivslktkvsvfskr 114
                 + ++ +    +++ v D++ +l+F V++ + ++s+s  +  +D +G++L+++r+  k  + ++W v + ++ e    +++++  s+  + + ++v +  
  EEA21741.1  26 IIMQCHDRLFNDVDVRDQSNELLFTVESkG-VNSMSWRRTVKDVTGTPLFQLRKlFKYGVDRKWSVEDPSGLE----LCSLRHVSTFRQFHALDVTVL- 118
                 55666666668899**************55.9**********************6699***********9995....9****9766665555555555. PP

                 .T--...-----SEEEES-TTTT--EEEE.CC--EEEEEEE---.--..-----B-SEEEEE-TTSBHHHHHHHHHH CS
         LOR 115 ksnvvvkeektedfeikGsflkrsckivd.esgklvAevkrKet.ik..gvllgkDvfklvvkpevDkaliiaLvvv 187
                   n+  ++ k++  +++ +  +   ++     g++vAe++  e   +  ++++ + v+k  v+ +vD  liia++++
  EEA21741.1 119 --NQ-ADGGKESAVNVRPK-DQVGITVQVkIRGATVAEIQMTEAnHShiNFTEDRSVWKAHVAGGVDLTLIIAIMLC 191
                 ..32.34455555555433.333444444599*******977665541155666669****************9986 PP

>> CdAMP_rec  Cyclic-di-AMP receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   4.3e-05      0.26      30      56 ..      12      38 ..       5      54 .. 0.88
   2 ?    0.9   0.0     0.086   5.1e+02      82     102 ..     134     154 ..     124     160 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 4.3e-05
                EEEEETTT-SEEEEEEEEEEGGGHHHH CS
   CdAMP_rec 30 lattGGflkeGnttlliGvedekvdev 56
                +a t Gf+++G+tt+++ ++d+  ++v
  EEA21741.1 12 VAITDGFIQAGETTIIMQCHDRLFNDV 38
                799*****************9988776 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.086
                 TT--SS--EEEEESEEEEEEE CS
   CdAMP_rec  82 dsyvpkpvevevGGatvfvld 102
                    v  +v+v++ Gatv  ++
  EEA21741.1 134 KDQVGITVQVKIRGATVAEIQ 154
                 55677889********97555 PP

>> MOSC_N  MOSC N-terminal beta barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   3.3e-05       0.2      12     113 ..      65     173 ..      55     178 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 3.3e-05
      MOSC_N  12 iKsckgvslseae.vtaaGllalDReflvvdedG.......kfltqrrePrl..alirteldeedglLtltapgrkdlevslakakasleevsvlelsa 100
                 +K ++g  l + + + + G    DR++ v+d++G       ++ t r++ +l    ++++   +++ + ++ +++  ++v+++++ a+ +e+++ e++ 
  EEA21741.1  65 VKDVTGTPLFQLRkLFKYG---VDRKWSVEDPSGlelcslrHVSTFRQFHALdvTVLNQADGGKESAVNVRPKDQVGITVQVKIRGATVAEIQMTEANH 160
                 5666666666655466777...5************9999998888888888732223333337899999999999999999999999999999999999 PP

      MOSC_N 101 sgldegdevakwl 113
                 s ++ +++ + w 
  EEA21741.1 161 SHINFTEDRSVWK 173
                 9888888877775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (201 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       493  (0.0274974); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.41u 0.27s 00:00:00.68 Elapsed: 00:00:00.41
# Mc/sec: 1469.27
//
Query:       EEA21742.1  [L=181]
Description: signal peptidase complex catalytic subunit SEC11, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
     0.0015   18.4   0.0     0.0037   17.2   0.0    1.7  1  Peptidase_S24  Peptidase S24-like


Domain annotation for each model (and alignments):
>> Peptidase_S24  Peptidase S24-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   2.1e-07    0.0037       2      52 ..      49     100 ..      49     134 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 2.1e-07
                    XXSSTTCCTXXTTXEEEEE.CTS---TTSEEEEEETTCE-EEEEEEEEETTE CS
  Peptidase_S24   2 vpGdSMeptlldGdlilVd.kfsepkrGdivvfrlpgeeeayiKrviglpgd 52 
                    v ++SM+p ++ Gdli+   + s ++ Gdi v+   g+   +++r ++  gd
     EEA21742.1  49 VISESMAPAFHRGDLIFLWnRPSLIHVGDIPVVWFSGNAYPMVHRAVQVYGD 100
                    569*************98636668999**99998888888999998877666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       261  (0.0145574); expected 358.6 (0.02)
Passed bias filter:                      195  (0.0108762); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.23s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1341.95
//
Query:       EEA21743.1  [L=224]
Description: hypothetical protein PMAA_055400 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (224 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       286  (0.0159518); expected 358.6 (0.02)
Passed bias filter:                      257  (0.0143343); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.29s 00:00:00.75 Elapsed: 00:00:00.48
# Mc/sec: 1401.61
//
Query:       EEA21744.1  [L=267]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      4e-58  195.8   0.0    4.9e-58  195.5   0.0    1.1  1  Protoglobin  Protoglobin


Domain annotation for each model (and alignments):
>> Protoglobin  Protoglobin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  195.5   0.0   2.7e-62   4.9e-58       2     158 .]      55     233 ..      54     233 .. 0.99

  Alignments for each domain:
  == domain 1  score: 195.5 bits;  conditional E-value: 2.7e-62
                  GHHHHHHHHHTT-SHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCTSHHHHHHHCH................HCHHHHHHHHHHHHHHHCCCSSCCHHH CS
  Protoglobin   2 earlayllsflglteedlaaLralapliealipavvdafYekllsfpetarifet................ssqierlkdflksyllklfsgpfdsay 83 
                  e+r++yl+sfl+++++d++aL +++++i+alipavv+++Y+kll++++tar+f+t                s+qi ++k+fl+ yl kl+s+p+++++
   EEA21744.1  55 EDRIHYLHSFLDFSSNDIEALINGSKYIKALIPAVVNIVYRKLLQYDITARAFQTrstsfegpldefpsedSPQIIHRKMFLRGYLVKLCSDPSKMEF 152
                  79************************************************************************************************ PP

                  HHHHHHHHHHHC......HCT--HHHHHHCHHHHHHHHHHHHCCCS.-SHHHHHHHHHHHHHHHHHHHHHHCGGGBXTTX. CS
  Protoglobin  84 veyldkvGkmht......rlgleprwyiaalglvqevlleallekeklsaaektalvkalnKliwldndlaleaYvregee 158
                  ++yldkvG+mh+      +l++e++++ a+l+++q++++ea+l+++++++++k+alvkal K+iw++ndl++++Y r+gee
   EEA21744.1 153 WQYLDKVGMMHVgrgrehPLHIEYIHIGACLSFIQDTFTEAILSHPRMQLHRKIALVKALGKVIWIQNDLFAKWYGRDGEE 233
                  ******************************************************************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (267 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       488  (0.0272185); expected 358.6 (0.02)
Passed bias filter:                      441  (0.024597); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 1734.75
//
Query:       EEA21745.1  [L=267]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      4e-58  195.8   0.0    4.9e-58  195.5   0.0    1.1  1  Protoglobin  Protoglobin


Domain annotation for each model (and alignments):
>> Protoglobin  Protoglobin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  195.5   0.0   2.7e-62   4.9e-58       2     158 .]      55     233 ..      54     233 .. 0.99

  Alignments for each domain:
  == domain 1  score: 195.5 bits;  conditional E-value: 2.7e-62
                  GHHHHHHHHHTT-SHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCTSHHHHHHHCH................HCHHHHHHHHHHHHHHHCCCSSCCHHH CS
  Protoglobin   2 earlayllsflglteedlaaLralapliealipavvdafYekllsfpetarifet................ssqierlkdflksyllklfsgpfdsay 83 
                  e+r++yl+sfl+++++d++aL +++++i+alipavv+++Y+kll++++tar+f+t                s+qi ++k+fl+ yl kl+s+p+++++
   EEA21745.1  55 EDRIHYLHSFLDFSSNDIEALINGSKYIKALIPAVVNIVYRKLLQYDITARAFQTrstsfegpldefpsedSPQIIHRKMFLRGYLVKLCSDPSKMEF 152
                  79************************************************************************************************ PP

                  HHHHHHHHHHHC......HCT--HHHHHHCHHHHHHHHHHHHCCCS.-SHHHHHHHHHHHHHHHHHHHHHHCGGGBXTTX. CS
  Protoglobin  84 veyldkvGkmht......rlgleprwyiaalglvqevlleallekeklsaaektalvkalnKliwldndlaleaYvregee 158
                  ++yldkvG+mh+      +l++e++++ a+l+++q++++ea+l+++++++++k+alvkal K+iw++ndl++++Y r+gee
   EEA21745.1 153 WQYLDKVGMMHVgrgrehPLHIEYIHIGACLSFIQDTFTEAILSHPRMQLHRKIALVKALGKVIWIQNDLFAKWYGRDGEE 233
                  ******************************************************************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (267 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       488  (0.0272185); expected 358.6 (0.02)
Passed bias filter:                      441  (0.024597); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1821.97
//
Query:       EEA21746.1  [L=588]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.4e-13   50.9   0.0    2.7e-13   49.9   0.0    1.5  1  DDE_1           DDE superfamily endonuclease
    8.5e-13   48.1   0.0    5.8e-12   45.5   0.0    2.5  2  HTH_Tnp_Tc5     Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
        3.8    7.5   7.2       0.52   10.2   1.5    2.5  2  Myb_DNA-bind_7  Myb DNA-binding like


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.9   0.0   4.5e-17   2.7e-13       6     171 ..     214     374 ..     209     378 .. 0.85

  Alignments for each domain:
  == domain 1  score: 49.9 bits;  conditional E-value: 4.5e-17
       DDE_1   6 vllcanaagsekLkplvigkaksprafkngektkkkldveyksnrkawltssifeeWLkvfdkrle..aekrkilLlldssrshetvel.leselqnik 101
                 +l+++++a ++ ++pl+i+ ak++ + ++  ++ +k d     ++ +   s+++ eW+++f   ++  a ++  lL +d++++h t el + + +++i 
  EEA21746.1 214 TLIECVSAAGKVIPPLIILAAKNHLEEWY--QHLEKEDYLVAFSKAGYSNSELIFEWIHHFAIETKkyAGSSWRLLFMDNFDAHITYELyEFCISKKIL 310
                 57999************************..888889999999999999*************999988889999***************999******* PP

       DDE_1 102 lvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketi 171
                 + ++P++++++lqPld + +++ K+    ++++++ ++    +k        d+l ++ k ++  ++k+ i
  EEA21746.1 311 VYTFPPNTTHILQPLDGVPFQNYKHFHGVEVNNQARAGGVVFDK-------YDFLFNLPKVREqTFTKKII 374
                 ****************9999999999988888888777666666.......55555555555555555555 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.5   0.0   9.7e-16   5.8e-12       3      61 ..      72     132 ..      70     137 .. 0.91
   2 ?   -1.9   0.1      0.59   3.5e+03       6      19 ..     236     249 ..     235     252 .. 0.79

  Alignments for each domain:
  == domain 1  score: 45.5 bits;  conditional E-value: 9.7e-16
                  HHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT..S CS
  HTH_Tnp_Tc5   3 elEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh..g 61 
                   +E+a++ Wi+ql+  g p+t+++i   A +++ +a    +p+ +++ +W++ F+kR+  g
   EEA21746.1  72 AEERAVKAWIEQLDIIGTPPTNRMITGCADAILARANPHLDPPRTVGPNWVYGFLKRLpdG 132
                  68*****************************9977788999****************9555 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.59
                  HHHHHHHHHHC-CT CS
  HTH_Tnp_Tc5   6 kaLleWirqlrerg 19 
                  ++L eW+++l ++ 
   EEA21746.1 236 NHLEEWYQHLEKED 249
                  6799****997665 PP

>> Myb_DNA-bind_7  Myb DNA-binding like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.4      0.35   2.1e+03      47      69 ..      11      33 ..       1      44 [. 0.69
   2 ?   10.2   1.5   8.7e-05      0.52      39      69 ..     523     553 ..     518     568 .. 0.80

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.35
  Myb_DNA-bind_7 47 lKFkkEerknpeliekalkkrke 69
                    + +kkEe   ++  ++ ++++++
      EEA21746.1 11 ETYKKEEDAIKNAYQSYIQNKNQ 33
                    56888888888888888887776 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 8.7e-05
  Myb_DNA-bind_7  39 krtrrqlKlKFkkEerknpeliekalkkrke 69 
                      r  +++K+K++ Eer ++++i++a ++ + 
      EEA21746.1 523 ARRAEEIKKKWRIEERARKRRIRQAKETSRV 553
                     68889*******************9766554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (588 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1186  (0.0661498); expected 358.6 (0.02)
Passed bias filter:                      616  (0.0343577); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.30s 00:00:00.95 Elapsed: 00:00:00.47
# Mc/sec: 3722.45
//
Query:       EEA21747.1  [L=424]
Description: exo-beta-1,3-glucanase (Exg1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.8e-14   53.9   6.6    5.7e-14   52.2   6.6    1.7  1  Cellulase  Cellulase (glycosyl hydrolase family 5)


Domain annotation for each model (and alignments):
>> Cellulase  Cellulase (glycosyl hydrolase family 5)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.2   6.6   3.2e-18   5.7e-14      14     245 ..      89     342 ..      83     396 .. 0.63

  Alignments for each domain:
  == domain 1  score: 52.2 bits;  conditional E-value: 3.2e-18
                 CETTSCGGSHHHHHHHHHHHT-SEEEEEEE.CTGGTTSSTTTGCTHHHHHHHHHHHHHHHHTT-EEEEEEESSTTTCSSSSTTTTHHH..HHHH..... CS
   Cellulase  14 stswgnpyttkalidevkdagfntvRlpvs.wgelvenapdykvdenslerveevvkyakenglyvildiHseegwltkadgnssedt..aeef..... 104
                 s +w   + t++ + ++ +ag+n+vR+p++ w  + ++++   + + +le +++++ +a ++gl+vi+d+H  +g    ++g +++ +  + ++     
  EEA21747.1  89 SQHWN-SFITADDFYQISSAGMNHVRIPIGyWAVMPQAGEP--YVQGQLEVLDQAIVWARDAGLKVIVDLHGVPGS---QNGFDNSGHrgSINWdkvpe 181
                 55674.469999*****************944444444444..5899*************************7333...33333333333333334444 PP

                 ....HHHHHHHHHHHHTTTTTTEE.EESSSS--STTCT...CCTCHHHTTHHHHHHHHHHHHHHHHTTSSEEEEECHHHHTBHHHHHCT...SGSSSST CS
   Cellulase 105 ....fkklwtqiAerykkndevvi.felmNEPhgnntg...aewtseeadevkayaeeaikaIRavgpnrliivegnswsgnldgavln...dPndsqd 192
                       +++ +++ery+  ++vv  +e +NEP  +  +   + w      ++++y+  +   +R+v+++  + +       +++    n    P     
  EEA21747.1 182 hisiALHAISALSERYAIHSDVVTsIEALNEPMTVMGDvgvNVW------TLQQYYYDCWGRLREVNQDTALTLHD--GFRDISF--WNgfmGPYSGVW 270
                 44443336999*****9888866449********8887666666......9******************6666666..3344444..222347855579 PP

                 TEEEEEEEETTTHHHTGCGS..................HSCTHHHHHHHHHHHHHHHHHHTTS.EEEEEEEE CS
   Cellulase 193 nliysvHfYgpsdfaqtefg..................kdltdktnlaqrledaakylvekgi.pviigEfG 245
                 n++++ H Y+  d +  +                    +++t + + ++ ++d akyl+ +g+ + + g fG
  EEA21747.1 271 NVMMDTHHYEVFDNGLLSLDtnghtqnvcafgnkaaatDKWTIVGEWTGAMTDCAKYLNGRGVgARWDGSFG 342
                 **********88876655524445555555555555544444444445555555555555555444555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (424 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       531  (0.0296168); expected 358.6 (0.02)
Passed bias filter:                      435  (0.0242624); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.30s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 2790.77
//
Query:       EEA21748.1  [L=1064]
Description: importin 11, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.8e-16   58.4   0.2    4.6e-14   52.1   0.2    3.1  2  IBN_N     Importin-beta N-terminal domain


Domain annotation for each model (and alignments):
>> IBN_N  Importin-beta N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.1   0.2   2.5e-18   4.6e-14       2      70 ..      38     105 ..      37     108 .. 0.94
   2 !    2.5   0.0    0.0078   1.4e+02      26      43 ..     570     587 ..     553     589 .. 0.83

  Alignments for each domain:
  == domain 1  score: 52.1 bits;  conditional E-value: 2.5e-18
                 HHHHHHHHCSTCHHHHHHHHHHCTTSHHHHHHHHHHHHHHHHHHHGGSCCCHCGSXHHHHHHHHHHHHH CS
       IBN_N   2 ekqLkqlekqpgflsallqilanseselevRqlAalyLknlitkhWsdeeekqslpseekeqIrnnlln 70 
                 ++qL+++ekq gf ++l++ + + +++le+R+l++++Lkn i+++W++++ + ++ +e+ke I+n++l+
  EEA21748.1  38 TQQLQHWEKQVGFYPLLQEAFLDHSLPLEIRYLSIIQLKNGIDRYWRKTASN-AIKKEDKERIKNKALE 105
                 59*********************************************66666.*************997 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.0078
                 TSHHHHHHHHHHHHHHHH CS
       IBN_N  26 eselevRqlAalyLknli 43 
                  ++l+vR  A+ +Lkn +
  EEA21748.1 570 VNDLPVRITAGRQLKNVL 587
                 5789************87 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1064 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       785  (0.0437838); expected 358.6 (0.02)
Passed bias filter:                      593  (0.0330749); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.84u 0.32s 00:00:01.15 Elapsed: 00:00:00.48
# Mc/sec: 6642.45
//
Query:       EEA21749.1  [L=115]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (115 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       199  (0.0110993); expected 358.6 (0.02)
Passed bias filter:                      164  (0.00914719); expected 358.6 (0.02)
Passed Vit filter:                         4  (0.000223102); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 797.10
//
Query:       EEA21750.1  [L=465]
Description: acid phosphatase PHOa [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      7e-35  120.9   4.6    2.7e-34  118.9   4.5    1.9  1  Phosphoesterase  Phosphoesterase family
  ------ inclusion threshold ------
      0.074   12.7   0.0       0.13   11.9   0.0    1.4  1  HIF-1a_CTAD      HIF-1 alpha C terminal transactivation domai


Domain annotation for each model (and alignments):
>> Phosphoesterase  Phosphoesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.9   4.5     3e-38   2.7e-34     112     356 .]      75     297 ..      62     297 .. 0.87

  Alignments for each domain:
  == domain 1  score: 118.9 bits;  conditional E-value: 3e-38
  Phosphoesterase 112 elaqeftlcDryFssvlggtepNrlflisgtsdpsGteggpsladpkktvlkgftqktigerLsekgvswaiYqealdnlakskva.......p 198
                         +++tl++ +  +v +++epN+ +  +g       ++ ++    ++ +  + +++t+++ L++kg+sw+ Yqe+l ++a+++          
       EEA21750.1  75 LASKGITLTNFW--AVSHPSEPNYAATAAGDL-----FAMDN----DDFIQIPANVSTVVDLLDTKGISWGEYQEHL-PYAGFQGFnysnqqtH 156
                      455677787766..9**********9999999.....66655....89999**************************.5555544444455569 PP

  Phosphoesterase 199 fnyyvrklkklearrkalkqlglaakq..lekfkkdvkngkLPqvsfikpngandeHpgadvaagdklikevlealtsspq.waktllivtyDE 289
                      +n+yvrk+++l  +++   +++ a ++  + +++ d+++++LPq +fi+pn++nd H++ +++++  +  +++e+l++s + w+++l+++t+DE
       EEA21750.1 157 TNDYVRKHNPLILYDNVAGNASRALQIknFTSLWSDIQKNTLPQWAFITPNMTNDAHDT-NISFASTWERNFVEKLENSTDfWNESLILLTFDE 249
                      ********************999988789******************************.********************************** PP

  Phosphoesterase 290 ngGfyDhVappvapvsdpdglkGdpyglgvrvPllviSpyakkgtvdhelfdhtSvlrfiekrfglp 356
                       g +      p+++   +       + lg  vP+ +i+      t d++++ h+S l+++++++glp
       EEA21750.1 250 TGDY------PIHN---K----VFSVLLGGAVPTELIG------TSDDTFYTHYSTLATVQANWGLP 297
                      **99......5222...1....1246788888888886......9********************97 PP

>> HIF-1a_CTAD  HIF-1 alpha C terminal transactivation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   1.4e-05      0.13       3      15 ..     295     307 ..     293     308 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 1.4e-05
  HIF-1a_CTAD   3 vLPeLtryDCEVN 15 
                  +LP L r+DC++N
   EEA21750.1 295 GLPSLGRWDCGAN 307
                  7***********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (465 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       639  (0.0356406); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.53
# Mc/sec: 2627.97
//
Query:       EEA21751.1  [L=470]
Description: peroxisome biosynthesis protein (Peroxin-2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.4e-39  134.4   2.1    6.1e-39  133.9   2.1    1.2  1  Pex2_Pex12    Pex2 / Pex12 amino terminal region
    0.00026   21.1   5.1    0.00054   20.1   5.1    1.5  1  zf-C3HC4_4    zinc finger of C3HC4-type, RING
  ------ inclusion threshold ------
      0.041   13.7   1.6      0.092   12.6   1.6    1.6  1  zf-C3HC4      Zinc finger, C3HC4 type (RING finger)
       0.12   12.4   4.0       0.43   10.7   4.0    1.9  1  zf-RING_UBOX  RING-type zinc-finger
       0.23   11.4   3.0       0.29   11.0   0.5    2.2  2  zf-C3HC4_2    Zinc finger, C3HC4 type (RING finger)


Domain annotation for each model (and alignments):
>> Pex2_Pex12  Pex2 / Pex12 amino terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  133.9   2.1   1.7e-42   6.1e-39       1     212 [.      84     278 ..      84     291 .. 0.91

  Alignments for each domain:
  == domain 1  score: 133.9 bits;  conditional E-value: 1.7e-42
  Pex2_Pex12   1 deelesllkpalryilrllagqrfpilnyfdEikllldlllelltlksgngTfgeefygLkrv.ssselkkrrllskrqrllsllllvlipYlkeklde 98 
                 deel +llk ++ ++l+++ g++    ++ +Ei+l+l+++l+ l+++ +n+++g  ++gL++v s+s++  +++++ +q+ l+ l++v++ Y++ek+++
  EEA21751.1  84 DEELLGLLKGQVGEALKYF-GAHAR-DEWSSEIQLALRAILFKLSIWDHNASYGAALQGLQYVdSRSKSVVSTPPTTWQKSLYGLFTVGGRYAWEKWES 180
                 89***************87.76666.6************************************888888889*************************** PP

  Pex2_Pex12  99 lysarerysaealsdearnsreslkkrlkrlllklypfiealyellnlvlqllYL.sgkyysllkrllgiryvrlnpadqrrnarrpsyeylnrqllwn 196
                 ++             ++r   +   +   rll ++  ++++ + ++++v +l++L +g+y +l++r+l+ir+++ +++ +    r +s+eylnrql+w+
  EEA21751.1 181 WL-------------IERENGYDEPSADIRLLSRITNLVSTTHSIAAFVSFLVFLvNGRYRTLIDRILRIRLAPPSNQVS----REVSFEYLNRQLVWH 262
                 **.............777777777777789********************************************999999....*************** PP

  Pex2_Pex12 197 alkellglllllllls 212
                 a++e+l +ll+l+ + 
  EEA21751.1 263 AFTEFLLFLLPLVGIG 278
                 ***********76554 PP

>> zf-C3HC4_4  zinc finger of C3HC4-type, RING
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   5.1   1.5e-07   0.00054      13      42 .]     359     388 ..     353     388 .. 0.93

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 1.5e-07
  zf-C3HC4_4  13 sleCGhsfClsCisslqkepdgeqllCplC 42 
                 +++CG+++C+ Ci++  + ++ge++ C  C
  EEA21751.1 359 TIPCGCIYCFVCITEKLEAEEGEGWYCLRC 388
                 79*************************999 PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   1.6   2.6e-05     0.092       1      41 []     320     388 ..     320     388 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 2.6e-05
                 -TTT-S--SS-E...........................E-TTS--B-CHHHHHHHHC..TSSB--TTT CS
    zf-C3HC4   1 CpiCleeakepn..........................elleCkHsfCskCirkilks..rkkvkCPlC 41 
                 C+iC + +  ++                          e+++C+  +C+ Ci++ l+    +  +C  C
  EEA21751.1 320 CAICYQDQNPTStseadilgsasggiigsaqtditnpyETIPCGCIYCFVCITEKLEAeeGEGWYCLRC 388
                 88888877777778888888888888888888888889****************999744344447766 PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   4.0   0.00012      0.43       1      27 [.     320     374 ..     320     388 .. 0.68

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00012
  zf-RING_UBOX   1 CpIClelft..........................dPlv.l.pCGHtFCreCl.we 27 
                   C IC+++ +                          +P   + pCG ++C  C+ ++
    EEA21751.1 320 CAICYQDQNptstseadilgsasggiigsaqtditNP-YeTiPCGCIYCFVCItEK 374
                   7777764445666777777777777777777777799.55559**********422 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.1      0.27   9.7e+02       2       7 ..     320     325 ..     319     333 .. 0.74
   2 ?   11.0   0.5   8.1e-05      0.29       9      35 ..     353     379 ..     350     385 .. 0.89

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.27
  zf-C3HC4_2   2 CpiCld 7  
                 C+iC++
  EEA21751.1 320 CAICYQ 325
                 999986 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 8.1e-05
  zf-C3HC4_2   9 lkdpsvvtpCgHvfCqkCilrsLeekn 35 
                 + +p  ++pCg  +C  Ci + Le+++
  EEA21751.1 353 ITNPYETIPCGCIYCFVCITEKLEAEE 379
                 679999***************999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (470 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       629  (0.0350828); expected 358.6 (0.02)
Passed bias filter:                      460  (0.0256568); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.48
# Mc/sec: 2955.81
//
Query:       EEA21752.1  [L=1040]
Description: hypothetical protein PMAA_055480 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1040 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       842  (0.046963); expected 358.6 (0.02)
Passed bias filter:                      595  (0.0331865); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.84u 0.31s 00:00:01.14 Elapsed: 00:00:00.49
# Mc/sec: 6440.81
//
Query:       EEA21753.1  [L=297]
Description: protein-ER retention receptor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.7e-44  151.1  10.0    6.7e-44  150.3  10.0    1.4  1  ER_lumen_recept  ER lumen protein retaining receptor
  ------ inclusion threshold ------
        0.6    9.9   7.5          1    9.2   0.2    3.5  3  PQ-loop          PQ loop repeat


Domain annotation for each model (and alignments):
>> ER_lumen_recept  ER lumen protein retaining receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  150.3  10.0   7.5e-48   6.7e-44       1     147 []      30     186 ..      30     186 .. 0.89

  Alignments for each domain:
  == domain 1  score: 150.3 bits;  conditional E-value: 7.5e-48
  ER_lumen_recept   1 svaGlSlktqilyalvfltryldlf.lylreeislyntlmkialillsiyiiylilvkfketyekekDtfklellivpsllla........llf 85 
                      s +G+Sl tqily lvfltryldlf ++++  +++yn+++k+++i +s+yiiy++ ++f +t+e+ek ++kl+ l ++ +l+a          +
       EEA21753.1  30 SSEGVSLLTQILYGLVFLTRYLDLFsTSHWAFYHAYNIFFKLFYIFSSLYIIYVMIYVFPRTREREK-SWKLASLCFLGALVAapsalgidAAI 122
                      579*********************8777777************************************.****9554444444435554444455 PP

  ER_lumen_recept  86 hpg..ssktllevlwtfsiiLesvAilPQlillqktgevesltshyvfalglyRalyllnWivr 147
                       ++   +++++e++w+fsi+Lesv++lPQl+ll++t+ +++++s y++alg+yRaly+lnW++r
       EEA21753.1 123 RRKsyPHEWFTETCWAFSIVLESVCVLPQLLLLRQTTVPTVIDSFYLVALGSYRALYILNWLIR 186
                      555799*******************************************************986 PP

>> PQ-loop  PQ loop repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.2   0.00012         1      21      50 ..      22      51 ..      22      60 .. 0.83
   2 ?   -2.5   0.7      0.52   4.7e+03      46      49 ..      77      80 ..      67      89 .. 0.49
   3 ?    3.7   0.0    0.0057        51       3      23 ..     134     154 ..     132     159 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00012
     PQ-loop 21 iikNykrkSteGlSilflllwllGdilsll 50
                i+ ++++ S eG+S+l+ +l  l ++++ l
  EEA21753.1 22 IWAIHRNNSSEGVSLLTQILYGLVFLTRYL 51
                899**************9998777776655 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.52
     PQ-loop 46 ilsl 49
                +l++
  EEA21753.1 77 SLYI 80
                2222 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.0057
     PQ-loop   3 eilgyislvlwlvsyiPQiik 23 
                 e++  +s+vl++v  +PQ+++
  EEA21753.1 134 ETCWAFSIVLESVCVLPQLLL 154
                 568899************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (297 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       593  (0.0330749); expected 358.6 (0.02)
Passed bias filter:                      291  (0.0162307); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 2137.63
//
Query:       EEA21754.1  [L=150]
Description: 60S ribosomal protein L27a, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.6e-23   82.6   0.0    5.5e-23   82.0   0.0    1.3  1  Ribosomal_L27A  Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27
  ------ inclusion threshold ------
       0.14   12.3   1.0        0.2   11.8   1.0    1.3  1  RAP             RAP domain


Domain annotation for each model (and alignments):
>> Ribosomal_L27A  Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.0   0.0   6.1e-27   5.5e-23       3     127 ..      28     147 ..      26     148 .. 0.88

  Alignments for each domain:
  == domain 1  score: 82.0 bits;  conditional E-value: 6.1e-27
                     GGTSSTTTTTTTTT-..S--........S--.........---GGG..---...EEEEHHHHHHTTTTGTTS.--......----EEEGGGTTTT CS
  Ribosomal_L27A   3 ktgGrGhkGqkkrsg..vkk.kpg.feGGqmplyrrlpkrGfknskfkkey...kvvnlkdLdelideerle.la......deaeeidleelaea 83 
                     ++gGrG++G +++++   +k +pg f  G++         G+++ + ++++   +++nl++L++li+ee++e         d+a ++dl +l   
      EEA21754.1  28 HPGGRGMAGGQHHHRtnLDKyHPGyF--GKV---------GMRHFHLQRNHywkPTINLDKLWSLIPEETREkYVsgsapsDKAIVLDLLSL--- 108
                     78***********9999899999999..***.........88866644555588***************99954489998888999999999... PP

                     SSS....SE.EEE--S---..--EEEESEE-HHHHHHHHHTT-EEE CS
  Ribosomal_L27A  84 glikkkdgv.Kvlgkgeltk.klkvkaskfSkkAkekIeaaGGkve 127
                            g+ Kvlgkg+l++ +l vka+++Sk+A+ kI++aGG +e
      EEA21754.1 109 -------GYaKVLGKGRLPEvPLVVKARYVSKEAERKIKEAGGVIE 147
                     .......***********9956*********************987 PP

>> RAP  RAP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   1.0   2.3e-05       0.2       5      32 ..      37      68 ..      34      90 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 2.3e-05
         RAP  5 Gpshyykns.knlt....gktklKkriLsklGy 32
                G +h+++ + ++++    gk+ +++++L++  y
  EEA21754.1 37 G-QHHHRTNlDKYHpgyfGKVGMRHFHLQRNHY 68
                4.45555555*******************9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (150 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       293  (0.0163422); expected 358.6 (0.02)
Passed bias filter:                      252  (0.0140554); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.35u 0.26s 00:00:00.61 Elapsed: 00:00:00.38
# Mc/sec: 1183.19
//
Query:       EEA21755.1  [L=418]
Description: translation factor pelota, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.6e-45  152.8   0.0      7e-45  152.2   0.0    1.3  1  eRF1_1    eRF1 domain 1
    1.5e-20   73.8   0.0      3e-20   72.8   0.0    1.5  1  eRF1_3    eRF1 domain 3
    3.9e-19   69.3   0.0    5.7e-19   68.8   0.0    1.3  1  eRF1_2    eRF1 domain 2


Domain annotation for each model (and alignments):
>> eRF1_1  eRF1 domain 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  152.2   0.0   1.2e-48     7e-45       1     128 [.       1     136 [.       1     137 [. 0.98

  Alignments for each domain:
  == domain 1  score: 152.2 bits;  conditional E-value: 1.2e-48
                 HEEEEECTBTTSCCEEEEEE-SCHHHHHHHHHCHTTHEEEEEEEECHHH.......--CEEEEEEEEEEEEEEECTTSSEEEEEEEEEEGGGG--TTSE CS
      eRF1_1   1 mkllkrdlekdgsgsvtLipeddedlwhlynliapgdsvrastvrkvqresstgsreservklkLtikvekvdfdkdagvlrisGkvieenehvklgaf 99 
                 m+l+k+++e++gsg vtL+pe++ed+wh+ynli+p+d +ra+++rkv++ +++g+++s+rv+l L+i+v+ +dfd+++++l++sG++++e +h+++g++
  EEA21755.1   1 MRLVKSSIEHNGSGAVTLCPEEPEDMWHAYNLIRPNDLLRATAIRKVTTAQESGTTVSQRVHLMLQIRVKGLDFDPNSSQLHVSGQIMNETQHTRIGQH 99 
                 9************************************************************************************************** PP

                 EEEEE-TTSEEEEEE........CEESHHHHHHHHHH CS
      eRF1_1 100 htldlelkrpftiik........eewdsfalerLkea 128
                 htldlel+r+ft++k         +wds+a+++Lk+a
  EEA21755.1 100 HTLDLELHRNFTLEKevgaegegVGWDSIAIDMLKDA 136
                 *******************997556**********98 PP

>> eRF1_3  eRF1 domain 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.8   0.0   4.9e-24     3e-20       1     113 []     290     394 ..     290     394 .. 0.91

  Alignments for each domain:
  == domain 1  score: 72.8 bits;  conditional E-value: 4.9e-24
                 HHHHHHHHHHHHHHHHCTCSSEEESHHHHHHHHHTT-EE....EEEEEHCHHTSSSH.HHHHS-HHH-HHHHHHHHHHHHHHHHHT.T-EEEEE-TTSH CS
      eRF1_3   1 liqekklleefleelakdtgkavYGveevlkalemgAve....tLLvseelersrdt.lkekvketgeelelvelieelvenvees.gakveiissese 93 
                 +++e+kl+++fl++l+kdt+ka+YG +ev++a+e gAv      L++s++l+rs+d+ ++++             +  lv+ v+e+ g++v ++ss++e
  EEA21755.1 290 YARETKLMDDFLDHLRKDTNKATYGPREVEHAVEQGAVGrgggVLIISNRLFRSQDVaERKR-------------WVGLVDRVREVeGGEVRVLSSDHE 375
                 689***********************************733336***********9977776.............89999999986489********** PP

                 HHHHHHHHTTTEEEEESS-- CS
      eRF1_3  94 eGeqlvkafgGiaaiLRykv 113
                 +G++l +++gG+aa+L ++v
  EEA21755.1 376 SGKRL-EGLGGVAALLTFPV 394
                 *****.************86 PP

>> eRF1_2  eRF1 domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.8   0.0   9.5e-23   5.7e-19       3     132 ..     148     286 ..     146     287 .. 0.91

  Alignments for each domain:
  == domain 1  score: 68.8 bits;  conditional E-value: 9.5e-23
                 EEEEEETTEEEEEEEESSCEEEEEEEE------BSTTBSCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHTTTESEEEEEESSTHHHHHHHHHHHHHH CS
      eRF1_2   3 glivldegeAtigllkgsrtevlkkievsvPkKhkrGgqsarrfeRlreekleeflkkvaeaankafllvdkdklkgiilagpgfvkeefldkdlldae 101
                  ++v++eg+A+i+++++ rt +++k+e+s+P+K+  Gg   + + +  +  l+  l+++  + + +  +++ ++ + i+la+pgfv+  f +++   a 
  EEA21755.1 148 VAVVMQEGLAHICFITQFRTILKQKVEMSIPRKRAGGGDHDKGLSKFFQVTLDTLLRQIEFNTSMTASNNNDETSRPILLASPGFVAAGFQKHIQSAAS 246
                 58*********************************9**********************987777774588888999**************999988888 PP

                 HHT.......CCEEEEE-S-TSCHHHHHHHHC..CHHHHC CS
      eRF1_2 102 lkk.......kviklvdvsyggesglnevlek..aaevlk 132
                  +          i++v++++g+ ++l+evl+   ++  l+
  EEA21755.1 247 TNMpalkrllPSIVVVHSASGYLHSLSEVLQSpsVKTLLS 286
                 88899999998999*****************987777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (418 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       541  (0.0301746); expected 358.6 (0.02)
Passed bias filter:                      484  (0.0269954); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.23s 00:00:00.76 Elapsed: 00:00:00.41
# Mc/sec: 3093.83
//
Query:       EEA21756.1  [L=430]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (430 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2503  (0.139606); expected 358.6 (0.02)
Passed bias filter:                      507  (0.0282782); expected 358.6 (0.02)
Passed Vit filter:                        84  (0.00468515); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.81u 0.35s 00:00:01.16 Elapsed: 00:00:00.52
# Mc/sec: 2482.49
//
Query:       EEA21757.1  [L=149]
Description: 40S ribosomal protein S19 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.7e-58  193.9   0.2    9.8e-58  193.7   0.2    1.0  1  Ribosomal_S19e  Ribosomal protein S19e


Domain annotation for each model (and alignments):
>> Ribosomal_S19e  Ribosomal protein S19e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  193.7   0.2   5.5e-62   9.8e-58       1     135 [.       5     140 ..       5     142 .. 0.98

  Alignments for each domain:
  == domain 1  score: 193.7 bits;  conditional E-value: 5.5e-62
                     TSSSHHHHHHHHHS--S---S-SSS-SSSS-SS-S-SS-SSTTTHHHHHHHHHHHTS--TTSGGGGS----SS-SSS-------THHHHHHHHHT CS
  Ribosomal_S19e   1 tvkdVpaeelikalaeeLkksgklevPewadlvKtgsakelapededWfyvRaAsilRkvylrgpvGverlrkvYGgkkrrgvrpshfvkasgsv 95 
                     tv+dV+a+++i a++++Lk++gkl +P w+d+vKt++++el+p+d dWfyvRaA+++R++ylr++vGv+rlrkv+G+ k+rg+rpsh+v+asg+v
      EEA21757.1   5 TVRDVDAQKFIGAYSAFLKRQGKLAIPGWVDTVKTSASNELPPQDADWFYVRAAAVARHIYLRKTVGVGRLRKVHGSPKNRGSRPSHHVDASGQV 99 
                     79********************************************************************************************* PP

                     TSSS--SSS---SS.-HHHHHTHHHHH--SS--S--XXXXX CS
  Ribosomal_S19e  96 irkilqqLeklglv.kkekkkgrrltkkGqrlldriaeeva 135
                      r++lq+Lek+g+v  +e+k+grr+t++Gqr+ldria++++
      EEA21757.1 100 DRRVLQALEKIGVVeIDEEKGGRRITQSGQRDLDRIAKTTV 140
                     **************8799999****************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (149 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       441  (0.024597); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.25s 00:00:00.72 Elapsed: 00:00:00.46
# Mc/sec: 979.27
//
Query:       EEA21758.1  [L=658]
Description: dual specificity phosphatase catalytic domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.2e-16   59.3   0.7    1.7e-15   58.2   0.7    1.5  1  Abhydrolase_6    Alpha/beta hydrolase family
    2.6e-15   56.8   0.0    9.8e-15   54.9   0.0    1.8  1  Abhydrolase_1    alpha/beta hydrolase fold
    2.4e-10   40.1   0.0    3.1e-09   36.5   0.0    2.1  1  Hydrolase_4      Serine aminopeptidase, S33
    5.3e-10   39.2   0.0    1.2e-09   38.1   0.0    1.5  1  DSPc             Dual specificity phosphatase, catalytic doma
    0.00049   20.0   0.6      0.005   16.7   0.1    2.4  2  Ser_hydrolase    Serine hydrolase
     0.0057   16.8   0.1     0.0097   16.0   0.1    1.3  1  Thioesterase     Thioesterase domain
     0.0071   15.9   0.0       0.02   14.5   0.0    1.7  2  Y_phosphatase    Protein-tyrosine phosphatase
  ------ inclusion threshold ------
      0.014   15.0   0.0       0.18   11.4   0.0    2.1  1  FSH1             Serine hydrolase (FSH1)
       0.11   12.6   0.0       0.23   11.6   0.0    1.5  1  PTPlike_phytase  Inositol hexakisphosphate
       0.17   11.4   0.0       0.26   10.8   0.0    1.2  1  LIDHydrolase     Lipid-droplet associated hydrolase


Domain annotation for each model (and alignments):
>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.2   0.7   9.6e-19   1.7e-15       1     192 [.     121     352 ..     121     384 .. 0.56

  Alignments for each domain:
  == domain 1  score: 58.2 bits;  conditional E-value: 9.6e-19
                    EEEE--GC.....GCHHHHHHHHCCT..CEEEEE--TTSTS-GGCS--HHH.....CHHH.HHHHCCTT........TTSEEEEEETCHHHHHHHH CS
  Abhydrolase_6   1 vlllHGagssassWlvapLaallaag..vhvlapDlpGhGrsdpppldled.....ladl.aalldelaa......gggpvvlvGHSlGGalalaa 82 
                    ++++HG+g+s  +++  pL+  l+    +  + +DlpG+G s+ +p ++e+     la+l a ++    +          vvl++HSlG++l++++
     EEA21758.1 121 LVFIHGLGGSLAQFH--PLLTSLSNVgpC--FGIDLPGCGLSSFAPKSWEAysieaLAELiAVAI----EehrdkaANQGVVLIAHSLGCSLSALL 208
                    79******9999998..887777888677..******************8855333233332222....233334546667**********99996 PP

                    HHCC...........EE.EEES-.....----TTT...............S----TTHHHHHHTT-C..CCCHCCH.......S-HS.CCCCHHH. CS
  Abhydrolase_6  83 apla.........lvvg.vlldp...pptalpagl...............laaalelllallallrl..lawlsre.......plpr.lfladed. 139
                    a++           + g ++++p   pp     +                +  +++l+++++++  +  l+++ ++       +  + +f a+   
     EEA21758.1 209 ASSSstvgtelkpYIQGvIAICPkasPP-----TAqetalarkllyiptpIFNLWRLWDRRGGAQSKsvLRFVGEKadpdtkqL--QiRFNAQSRs 297
                    666699999999987888*****55444.....333322122222232222222222222222222223333322233222221..0233332222 PP

                    .....C.CCCHCHCCCGHHHHCCHHCHTTCCHHTT-TTGCEEE.CTT-CHHHHCHHCCCH CS
  Abhydrolase_6 140 .....a.daawrarlarlaallaglgllpaaawadlpvpllvl.ggeDplvprllerlla 192
                         + + a  ++++++++   ++g    a wa + vpll++ g+eD++ +  + +++ 
     EEA21758.1 298 dvwrrMaWGALPVYDSHGQPIGGMPG---QAVWANVKVPLLLVaGDEDAVTK--ATEAAK 352
                    22211123333333333334444444...88999999999988457777554..223333 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.9   0.0   5.4e-18   9.8e-15       1     232 [.     119     352 ..     119     363 .. 0.90

  Alignments for each domain:
  == domain 1  score: 54.9 bits;  conditional E-value: 5.4e-18
                    SEEEEE-STTTCGGGGTTGHHHHHHHHTTSEEEEEEETTSTTSSSTTTGB.CHHSHHHHHHHHH.HH...HHHCTTSSEEEEEETHHHHHHHHHHH CS
  Abhydrolase_1   1 pvlvilhGlpgssdvwaerglapaLakdgfdvillDlrGvgySspapacinddygtasvaddld.ri...ldalgddkltlvGhSmGGmialayaa 92 
                    p lv++hGl+gs+  ++   l   L+     ++++Dl+G+g Ss+ap +  + y++ ++a+ +  +i   +d+  ++ ++l++hS+G+ +++ +a+
     EEA21758.1 119 PMLVFIHGLGGSLAQFHP--LLTSLSN-VGPCFGIDLPGCGLSSFAPKSW-EAYSIEALAELIAvAIeehRDKAANQGVVLIAHSLGCSLSALLAS 210
                    679***************..**99*98.*****************99866.89***********98899*************************** PP

                    HH.......GGGEEEEEEESECSSCCHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHHHHCCSCHHHHHHHHHHHHHHHCHHHCCHHHHHHHCHHH CS
  Abhydrolase_1  93 ey.......perVkalvllgaidpaaslieaqrqqaksfpdffdgyaadcarnpagplladelaaleqrhrlvdalkfpdkskrfpssgsdnassl 181
                             + ++++++++++   +as+  aq++++++   +  + +    r ++ + +a +   l++  +       +d + +  + +++ +s +
     EEA21758.1 211 SSstvgtelKPYIQGVIAICP---KASPPTAQETALARKLLYIPTPIFNLWRLWDRRGGAQSKSVLRFVGEK------ADPDTKQLQIRFNAQSRS 297
                    *********************...999999999999999999999999999999999999888888888776......999999999999999999 PP

                    HHHHHHHHHHHHHCCHHHHHHHHHC.....THHHHSEEEEEEETTCSSSCHHHHHH CS
  Abhydrolase_1 182 atgalksieqwpttdsaklllrlre.....lknvlaptlvisgtsDplvppkaled 232
                    + +   ++   p++ds+  +   ++       nv++p l+++g++D +++  +  +
     EEA21758.1 298 DVWRRMAWGALPVYDSHG-QPIGGMpgqavWANVKVPLLLVAGDEDAVTKATEAAK 352
                    999999999999999965.33334478899999999***********999866655 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.5   0.0   1.7e-12   3.1e-09       4     221 ..     118     361 ..     115     369 .. 0.81

  Alignments for each domain:
  == domain 1  score: 36.5 bits;  conditional E-value: 1.7e-12
  Hydrolase_4   4 kavvvlvHGlaehsgryaelaeaLaaqGfavyalDhrGhGrse..gkrghvpsfddyvdDlaafvekvkeehpelplfllGhSmGGliallyl..... 94 
                     +v++HGl+ +  +++ l   L + G  ++++D  G G s   +k ++  s++ + + +a ++e+++++  ++ ++l++hS+G  +++l++     
   EEA21758.1 118 IPMLVFIHGLGGSLAQFHPLLTSLSNVG-PCFGIDLPGCGLSSfaPKSWEAYSIEALAELIAVAIEEHRDKAANQGVVLIAHSLGCSLSALLAsssst 214
                  5679************************.589***********999*******************************************999977666 PP

  Hydrolase_4  95 ..lrypdkvaglilsaPalkikaklkappllklllkllgkllpklqv................snnlkadslsrdpevvaayeadplvhgkitvrlll 174
                    ++ ++ ++g+i ++P  ++++    ++l++ ll +  +++  +++                 ++ ++d  + + ++ a+ ++d + + +  +  ++
   EEA21758.1 215 vgTELKPYIQGVIAICPKASPPTAQ-ETALARKLLYIPTPIFNLWRLwdrrggaqsksvlrfvGEKADPDTKQLQIRFNAQSRSDVWRRMAWGALPVY 311
                  66444447**********9999774.78899999*************999888888888888766666666666666666666666655555444455 PP

  Hydrolase_4 175 elld...amkrleeraakitlPllllhGeaDkvvdpeasrelyerlgskd 221
                  + +    +++  ++  a++++Plll+ G++D v++  ++++++e +  +d
   EEA21758.1 312 DSHGqpiGGMPGQAVWANVKVPLLLVAGDEDAVTKATEAAKIVEFMEGSD 361
                  44432225566677777777***************999988887666555 PP

>> DSPc  Dual specificity phosphatase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.1   0.0   6.7e-13   1.2e-09      19     127 ..     521     643 ..     512     647 .. 0.75

  Alignments for each domain:
  == domain 1  score: 38.1 bits;  conditional E-value: 6.7e-13
                 CSEEEEESSSSSEC..ECCTTTTSEEEEEC.CES.....STTSCCGGGHHHHHHHHHHH......HHTT-EEEEEESSSSSHHHHHHHHHHHHHHTSCH CS
        DSPc  19 itlvinvtkevpna..nalkkseieklrip.ved.....ehetkiskyleeavefidka......kqkgkkvlVHCqaGisRSatliiaYlmktknlsl 103
                 i +vi++++e+p +  ++l+k +i++ + p v++     +++ ++    +++ + i +          +  v VHC  G +R++ li+ Yl+++k++ +
  EEA21758.1 521 IYAVIDISHENPVYdpYELEKGGIHYHKHPtVSKipptpDETRDFIGLVDQLEKEITEKtgkddgDPTRPLVGVHCHYGFNRTGFLIVSYLIERKGYAV 619
                 667888887777767777777888888888666677666666777777777777776553422222233469*************************** PP

                 HHHHHHHHHHS.TT-SSTHHHHHHH CS
        DSPc 104 neayeflkerr.paispnagfirqL 127
                 ++a++ +++ r p i+  ++fi +L
  EEA21758.1 620 QDAIDEFQKCRpPGIRH-DHFIDTL 643
                 *********99555555.5999887 PP

>> Ser_hydrolase  Serine hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.1   2.8e-06     0.005      51      93 ..     187     235 ..     165     253 .. 0.74
   2 ?    0.5   0.0      0.26   4.7e+02     112     140 ..     329     357 ..     322     370 .. 0.80

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 2.8e-06
                    HC-STTEEEEEETCHHHHHHHHHH......HTTSSSEEEEEEET--SGG CS
  Ser_hydrolase  51 eaaeekvvlvAHSlgclavlhaae......lqlakkvagalLVapadve 93 
                    +aa++ vvl+AHSlgc +++ +a+       +l+  ++g++ + p +  
     EEA21758.1 187 KAANQGVVLIAHSLGCSLSALLASssstvgTELKPYIQGVIAICPKASP 235
                    4566779************999987766666667778888888877653 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.26
                    HHCCHCEEEEETTBTTC-HHHHHHHHHHC CS
  Ser_hydrolase 112 klpfpslvvaSenDpyvsfeeaeelaeaw 140
                    + ++p l+va ++D + + +ea+++ e +
     EEA21758.1 329 NVKVPLLLVAGDEDAVTKATEAAKIVEFM 357
                    5678999***************9998765 PP

>> Thioesterase  Thioesterase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.1   5.4e-06    0.0097       3      80 ..     121     205 ..     119     219 .. 0.86

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 5.4e-06
                   EEEE--TTCCSGGGHHHHHHCTTCEEEEEEECSTTST.....SHHHCTTCHHHHHHHHHHHHHHH-SSS...SEEEEEETHHHHHH CS
  Thioesterase   3 LflfppagGsasvfrslasklsdpvvevlavqlpgre.....rdepplesieelaaeyaealrqiqpeg...PyalfGhSlGgllA 80 
                   L+  ++ gGs ++f+ l ++ls  v+  +++ lpg +      ++ ++ sie+la+ +a a++++ ++     ++l+ hSlG+ l 
    EEA21758.1 121 LVFIHGLGGSLAQFHPLLTSLSN-VGPCFGIDLPGCGlssfaPKSWEAYSIEALAELIAVAIEEHRDKAanqGVVLIAHSLGCSLS 205
                   7889*******************.8***********99887667788999*******999999888765333689999****9986 PP

>> Y_phosphatase  Protein-tyrosine phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       2.1   3.8e+03     141     188 ..     163     209 ..     158     214 .. 0.76
   2 !   14.5   0.0   1.1e-05      0.02     148     193 ..     558     612 ..     521     638 .. 0.69

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 2.1
                    SSS-SSSSGSCCHHHHHHHHHHHHHHSTTSS-EEEECSSSSHHHHHHH CS
  Y_phosphatase 141 tnWpdhgvpesaksllklirkvekskeaksgpvvVhCsaGvgRtgtfv 188
                    ++W+  ++ + a+ +   i++ + +  a++g v++  s G++ ++ ++
     EEA21758.1 163 KSWEAYSIEALAELIAVAIEEHRDKA-ANQGVVLIAHSLGCSLSALLA 209
                    67777777776777777777777777.899999999999999887765 PP

  == domain 2  score: 14.5 bits;  conditional E-value: 1.1e-05
                    SGSCCHHHHHHHHHHHHHH.........STTSS-EEEECSSSSHHHHHHHHHHHH CS
  Y_phosphatase 148 vpesaksllklirkveksk.........eaksgpvvVhCsaGvgRtgtfvaldil 193
                    +p+++++++ l++++ek+          ++++  v VhC  G +Rtg +++  ++
     EEA21758.1 558 TPDETRDFIGLVDQLEKEItektgkddgDPTRPLVGVHCHYGFNRTGFLIVSYLI 612
                    345566666666666665599999998666666677***********99976544 PP

>> FSH1  Serine hydrolase (FSH1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0    0.0001      0.18     103     191 ..     192     364 ..     163     384 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.0001
        FSH1 103 fdGiiGFSqGaalaallaslleellkeashpslkfailvsGfkleepk................................................... 150
                  + +i  S G+ l+allas  ++  +e  +p ++ +i+++  +++++                                                    
  EEA21758.1 192 GVVLIAHSLGCSLSALLASSSSTVGTE-LKPYIQGVIAICPKASPPTAqetalarkllyiptpifnlwrlwdrrggaqsksvlrfvgekadpdtkqlqi 289
                 366789999999999999999988876.58888888888888886666788888888888888888888888888888888888888888888899999 PP

        FSH1 151 .................................yeeyyeedkiqtptLhvlGelDtvvdeerseaLaeafkns...s 191
                                                          ++++p L v G++D+v + +++ +++e ++ s   s
  EEA21758.1 290 rfnaqsrsdvwrrmawgalpvydshgqpiggmpG--QAVWANVKVPLLLVAGDEDAVTKATEAAKIVEFMEGSdvdS 364
                 9988888888888888888885555544444221..22356789************************999865443 PP

>> PTPlike_phytase  Inositol hexakisphosphate
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   0.00013      0.23      84     152 ..     524     610 ..     452     613 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00013
                      ........EE-HHHHHHHTT-EEEEEEE-TTS---HHHHHHHHHHHHTS-T..............T-EEEEE-SSSSHHHHHHHHHH CS
  PTPlike_phytase  84 e....tpeevyerelaeelslrYaRipitdekapeeedfdalvsilkeape..............ktalvfnCqmGrgRTTtamvia 152
                            ++ vy+ +  e+ +++Y+  p   +  p++ +  +++ ++ ++++              ++ + ++C+ G  RT + +v +
       EEA21758.1 524 VidisHENPVYDPYELEKGGIHYHKHPTVSKIPPTPDETRDFIGLVDQLEKeitektgkddgdptRPLVGVHCHYGFNRTGFLIVSY 610
                      0334467889999999999******************************666************889999**********9887765 PP

>> LIDHydrolase  Lipid-droplet associated hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00014      0.26      70     120 ..     175     232 ..     120     261 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00014
  LIDHydrolase  70 dflkellek.aksekdvklilvGHSvGaYialevlkrlsers......ikkvvlLfPt 120
                   +++  ++e+ ++++ ++ ++l++HS G+ ++  ++++ s+        i++v+ ++P 
    EEA21758.1 175 ELIAVAIEEhRDKAANQGVVLIAHSLGCSLSALLASSSSTVGtelkpyIQGVIAICPK 232
                   444445554566889**************9999999777766789999********95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (658 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       501  (0.0279436); expected 358.6 (0.02)
Passed bias filter:                      465  (0.0259356); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.74u 0.32s 00:00:01.06 Elapsed: 00:00:00.52
# Mc/sec: 3783.70
//
Query:       EEA21759.1  [L=598]
Description: mitochondrial dihydroxy acid dehydratase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.8e-212  706.0   0.7   3.3e-212  705.7   0.7    1.0  1  ILVD_EDD  Dehydratase family


Domain annotation for each model (and alignments):
>> ILVD_EDD  Dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  705.7   0.7  1.8e-216  3.3e-212       2     517 .]      61     593 ..      60     593 .. 0.98

  Alignments for each domain:
  == domain 1  score: 705.7 bits;  conditional E-value: 1.8e-216
    ILVD_EDD   2 piigiansyselvpchvhlkelaeavkegveeaggvpaefntigvsDgiamgeegmrysLpsReliadsvetmleaqllDalvlisgCDKivPgllmaa 100
                 p+ig+a++++e +pc++hl +l+++vk+++++ g +++++nt+gvsDgi+mg+egmr+sL++Reliads+et+++aq +Da++ i+gCDK++Pg++m++
  EEA21759.1  61 PQIGVASVWWEGNPCNMHLLDLGKTVKKAITDRGSIAWQYNTVGVSDGITMGTEGMRFSLQTRELIADSIETVTCAQYHDANISIPGCDKNMPGVIMGM 159
                 9************************************************************************************************** PP

    ILVD_EDD 101 arlniPaifvsgGpmeagkkk....kldlssvfeavgalaagkis............eeeleeleeaacpgaGsCsgmgTAntmaclaealGlslpgsa 183
                 ar+n+P+i+++gG+++ g ++    ++++s++fea+ga+a++++             +e +e+le++acpgaG+C+gm+TAntma+++e +Gl+lpgs+
  EEA21759.1 160 ARHNRPSIMIYGGTIAVGYSEllrkRINISTCFEAAGAYAYDTLRqpddggdtsknkDEIIEDLERHACPGAGACGGMFTANTMATAIESMGLTLPGSS 258
                 *****************8866677799**************9999999999999998999*************************************** PP

    ILVD_EDD 184 sipatsaerkelaeeagkrivelvekdlkprdiltkeafeNAivvllalGGStNavlHllAiAreagveltlddfdelsrkvpllaklkPsgkydmedl 282
                 s+pa+s+++++++ +a+ +i  ++e+d++pr++ltk++feNA+v+++alGGStNavlH+lA+Ar+a+v+ltlddf+++s+k+p++a+l+Psgk++m dl
  EEA21759.1 259 STPAESPTKMRECVKAADAIHVCIEQDITPRKLLTKRSFENALVMTMALGGSTNAVLHFLAMARTAEVDLTLDDFQRVSNKIPFIADLAPSGKHYMADL 357
                 *************************************************************************************************** PP

    ILVD_EDD 283 hraGGvpavlkeLlkagllhgdvltvtgktlaenlee..aevkeqdvirplekplskegglavLkGnLapeGavvKtsaveeellkfegpArvfdseee 379
                 + +GG+p+v k L +agll+gd+ tvtgktla+n+e+  + +++q +irpl++p++++g++++L+GnLap+Gav+K++++e   lkf+g+Arvf++e+e
  EEA21759.1 358 YDVGGIPSVHKLLIAAGLLDGDIPTVTGKTLAQNVESfpSLAQDQAIIRPLNNPIKPTGHIQILRGNLAPGGAVAKITGKE--GLKFTGKARVFNKEHE 454
                 ***********************************9976666**************************************9..**************** PP

    ILVD_EDD 380 aveailkgkikagd..vvviryeGPkGgpGmpEmlkptsallgkglgkkvalitDGRfSGaskglvighvsPEAaegGpialvedGDiieidiekrtle 476
                 + +a++k++i +++  v+++ryeGPkGgpGmpE+lk+++al+g++l  +val+tDGR+SGas+g+++gh++PEAa+gGpialv+dGD+i+id+e+++l+
  EEA21759.1 455 LNDALAKSQIPRDEnlVLIVRYEGPKGGPGMPEQLKASAALMGAKL-ANVALLTDGRYSGASHGFIVGHIVPEAAVGGPIALVQDGDVITIDAETNELK 552
                 *****99****99999****************************99.9*************************************************** PP

    ILVD_EDD 477 levseeelaaRraawkp.ekkvktrgllakyaklvssaseGA 517
                 ++vseeel++R ++w+p +++v trg++akya+lv +as+GA
  EEA21759.1 553 MDVSEEELERRLKSWQPpKPQV-TRGVMAKYARLVGDASHGA 593
                 *****************44444.5*****************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (598 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       347  (0.0193541); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.30s 00:00:00.88 Elapsed: 00:00:00.48
# Mc/sec: 3721.52
//
Query:       EEA21760.1  [L=192]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.2e-28   97.3   0.6    1.3e-27   96.7   0.6    1.2  1  DUF1772   Domain of unknown function (DUF1772)


Domain annotation for each model (and alignments):
>> DUF1772  Domain of unknown function (DUF1772)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   96.7   0.6   7.4e-32   1.3e-27       1     135 [.      23     184 ..      23     186 .. 0.89

  Alignments for each domain:
  == domain 1  score: 96.7 bits;  conditional E-value: 7.4e-32
     DUF1772   1 GlilafslfvvPallslpasssl.............llkqwrrlfkrgkavfpplallsalafayla......araasrgarllylaaaallllsivpy 80 
                 G+i+++s+f++P+ll   a+s++             +++qw+ ++++gk++fp++a++s+l++ ++a      + a +r+ +lly + aa l + i+p+
  EEA21760.1  23 GGIISISIFTIPSLLLKRAPSANtrtattlaapishIARQWQYAYDIGKKLFPSMAVTSSLLYSFAAytlgkeRGATCRQVSLLY-T-AAGLNIMIAPF 119
                 89*************99999988*****************************************7778***98888888888888.5.4555556**** PP

     DUF1772  81 TllvmvPtNnkLaal.........k.eedakekedeaevrellerWgrlnlvRavlalaaavlgl 135
                 Tll++v +Nn +a           + +eda+ +++e+e    le+W+ ln++R +++la+a lg+
  EEA21760.1 120 TLLAIVAVNNVIAPYttgkhdlpvDaKEDAQYEQTEKEFVGQLEKWSLLNVIRGLFPLAGAGLGA 184
                 *********9988889999988885688888888888888889********************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (192 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       518  (0.0288917); expected 358.6 (0.02)
Passed bias filter:                      341  (0.0190195); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 1329.84
//
Query:       EEA21761.1  [L=459]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.3e-09   36.8   0.0    1.1e-08   35.8   0.0    1.6  1  2OG-FeII_Oxy_3  2OG-Fe(II) oxygenase superfamily


Domain annotation for each model (and alignments):
>> 2OG-FeII_Oxy_3  2OG-Fe(II) oxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.8   0.0   6.4e-13   1.1e-08       2      94 ..     136     223 ..     135     225 .. 0.75

  Alignments for each domain:
  == domain 1  score: 35.8 bits;  conditional E-value: 6.4e-13
                     EEEEE-TT-EEEEE-SS----TT.-.EEEEEEEEE....ET-B--EEE..........---TT-E.....EEEE-..B-TEEE--B.-SS-EEEE CS
  2OG-FeII_Oxy_3   2 qvlrygegqeykpHvDnfekeegsgqrrltvllyLnekeseeGGelelyekdkeavkikpkkgrl.....vlFesdellpHevlpvtkggeRlsl 91 
                     ++l+y+eg ++ pH+D+    e+++ + +t+++ L  ++++eGGe+ + +k  e+ k++   ++      +++++d +  Hev+pv++ g R++l
      EEA21761.1 136 KLLIYEEGAFFLPHQDS----EKADGMFATLVISL--PSKHEGGEVIVSHK-GESLKFETGSNSEygfswAAWYADVM--HEVKPVRS-GYRIVL 220
                     7899************6....45578*********..4679****999444.44444443333334444499999988..******66.5**999 PP

                     EEE CS
  2OG-FeII_Oxy_3  92 tgw 94 
                     +++
      EEA21761.1 221 VYN 223
                     865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (459 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       313  (0.0174578); expected 358.6 (0.02)
Passed bias filter:                      298  (0.0166211); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.23s 00:00:00.72 Elapsed: 00:00:00.40
# Mc/sec: 3485.17
//
Query:       EEA21762.1  [L=309]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       605  (0.0337442); expected 358.6 (0.02)
Passed bias filter:                      487  (0.0271627); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2063.59
//
Query:       EEA21763.1  [L=438]
Description: glutamate-1-semialdehyde 2,1-aminomutase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      2e-44  151.9   1.2    3.5e-43  147.8   1.2    2.0  1  Aminotran_3  Aminotransferase class-III


Domain annotation for each model (and alignments):
>> Aminotran_3  Aminotransferase class-III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  147.8   1.2     2e-47   3.5e-43       7     335 ..      50     349 ..      47     375 .. 0.87

  Alignments for each domain:
  == domain 1  score: 147.8 bits;  conditional E-value: 2e-47
                  --SCEEEEEEEBTEEEETTS-EEEESSHHHHTTTT-BT-HHHHHHHHHHHTT-S---TTTCEEHHHHHHHHHHHHHCT-..SEEEEESSHHHHHHHHH CS
  Aminotran_3   7 dnlllvitkaeGvyltdvdgkrylDlvssiavvnlGhahPkvvkavkeqaaklshvsfgaltnepalklaekllklapkgldkvflansGseAvetAl 104
                  d++++ ++ ++   +t +dg +y D+++ + +++ Gh++P ++ a++++++++ + + ga+t ++   ++ ++ k +    +++ + nsG+eA+  Al
   EEA21763.1  50 DPFPIYMKHGKSYQVTSEDGITYTDMAGEFTAALYGHSNPVILSAMNDVLQNVGMNI-GATTAQE-RLFTSEICKRFQL--ERMRFTNSGTEANLHAL 143
                  56779999********************************************95444.6666555.5566677777655..9**************** PP

                  HHHHHHHHHTSHCTT-EEEEETTT---SSHHHHHHSS--TTTTTTCTTB-TSEEEE-TTBGGGTB-HHHHHHHHHHHHHHHH.CHTCCCEEEEEE-SC CS
  Aminotran_3 105 KlarkyarekkatektkiiafkgafHGrtlgalsvtgskkkyktlfgpflpevvrlkypdeevlkeneeeeaalleeleale.kkkkdevaAvivEpi 201
                   +ark       t k k+++f+g++HG +l+  s +++    ++++   + + + +ky+d                 l a + +  ++ vaAv+vE +
   EEA21763.1 144 AAARK------FTGKRKVVTFSGGYHGAVLM-FSGGRP---ASNNV--DMDDWIVVKYND-----------------LDAAKeAIRSPGVAAVLVEGM 212
                  *****......****************9864.566666...22222..256777888887.................233222456799********* PP

                  ETTTTSEB--CCHHHHHHHHHHHHT-EEEEE-TTTTTTTTSSSSGGGGCTS--SEEEE-GGGGTTSS-EEEEEEHHHHTTS-TTS.....B--TTTT- CS
  Aminotran_3 202 qgegGvvvaspeflaklrelckkhdvllivDEvqtGfGrTGklfAlehagvspDlmtlaKaltgGlplsavlataevmqalapgs.....hgsTfgGn 294
                  qg+ G +  + efl+++++   + +vl+i DEv+t     G l Al   g++pDl t++K l+gGl +  + ++a+vm a+ p       h++Tf  n
   EEA21763.1 213 QGANGSICGTSEFLQGIQQASSEVGVLFILDEVMTSRISAGGLAALR--GLKPDLKTFGKYLGGGLAFGSFGGRADVMAAFDPRLngyisHSGTFNNN 308
                  ************************************99999898888..********************************987688999******** PP

                  HHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHCTT- CS
  Aminotran_3 295 placavalavleiieeekllenaqelgaalkegLeelqkky 335
                  +l   v +  l+ + + ++++   e+g++++e+L+e+ k  
   EEA21763.1 309 TLVTHVGHVGLTKVFTPEVARSFTEVGDKFREKLNEVTKGT 349
                  ***********************************998754 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (438 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       377  (0.0210274); expected 358.6 (0.02)
Passed bias filter:                      349  (0.0194657); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.26s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2888.58
//
Query:       EEA21764.1  [L=370]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
  ------ inclusion threshold ------
      0.032   14.7   0.8      0.032   14.7   0.8    3.2  3  Protamine_P2  Sperm histone P2


Domain annotation for each model (and alignments):
>> Protamine_P2  Sperm histone P2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   0.8   1.8e-06     0.032       8      89 ..     113     195 ..     109     198 .. 0.71
   2 ?   -3.6   4.0      0.91   1.6e+04      59      78 ..     248     267 ..     200     274 .. 0.53
   3 ?    2.6   0.3     0.011   1.9e+02      21      69 ..     309     357 ..     299     362 .. 0.68

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.8e-06
  Protamine_P2   8 sPsesPqqgsgqqaekeeqdqeqelspedvevyGrthrGryhyrhrrcsrrrrkri....krrrrrscrrrrrrrscrrrrrrrrg 89 
                   +Ps sP  g+++ +++e+q+q+q++   d   yG th G y     +  r +r+ i    +++r+ + r   +  + +r  ++rrg
    EEA21764.1 113 APSSSPSFGYQHPQHHEQQQQQQTM---DFYNYGSTHTGSYALEPTSSKRPKRQMIpntlSSQRNSPVRILPHPDGLQRLEHERRG 195
                   69999*9999999999888888887...6889********9988777666544433111145565566666666666666666665 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 0.91
  Protamine_P2  59 rrkrikrrrrrscrrrrrrr 78 
                   r  + +++ r   r  rrr+
    EEA21764.1 248 RYGKNTSEARLQMRMLRRRK 267
                   22222222223333333333 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.011
  Protamine_P2  21 aekeeqdqeqelspedvevyGrthrGryhyrhrrcsrrrrkrikrrrrr 69 
                   ae++ q q + l+ +  e +  t     ++r  +  r r++++++r+r+
    EEA21764.1 309 AEEQIQSQLKCLHDDGSENEFATTSPGIEHRELQSPRARTTTFTSRKRK 357
                   4556666778888888888877777777888888888888775544332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (370 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       759  (0.0423336); expected 358.6 (0.02)
Passed bias filter:                      333  (0.0185733); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.39
# Mc/sec: 2845.05
//
Query:       EEA21765.1  [L=310]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-06   28.6   0.8      0.069   13.4   0.1    2.4  2  Myb_DNA-bind_6   Myb-like DNA-binding domain
    0.00056   20.0   1.1     0.0014   18.8   0.2    2.0  2  Myb_DNA-binding  Myb-like DNA-binding domain


Domain annotation for each model (and alignments):
>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.1   7.7e-06     0.069       1      41 [.      45      83 ..      45      99 .. 0.83
   2 !   13.3   0.1   8.6e-06     0.077       8      50 ..     194     237 ..     191     240 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 7.7e-06
  Myb_DNA-bind_6  1 WteeEdeiLlklvekygndWknIaealnrRtpkqcfdrwkn 41
                    WteeE+  L++  + +   +k+Ia +l+ +t ++c+ ++++
      EEA21765.1 45 WTEEEEAYLVRTRM-HKMPYKHIAAHLK-KTELACRLHYHQ 83
                    *********88755.44789********.**********98 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 8.6e-06
  Myb_DNA-bind_6   8 iLlklvekyg.ndWknIaealnrRtpkqcfdrwkn.kLrpkisrk 50 
                     +L  ++e+y+ + W++I+++++ R++ ++  +w +  + +++s++
      EEA21765.1 194 RLHAIYEAYSaSFWSKISTEYS-RDSREINPKWAEkAIMSSFSHS 237
                     677899***9457*********.**********994445666655 PP

>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.2   1.5e-07    0.0014       3      44 ..      44      83 ..      42      84 .. 0.87
   2 ?   -1.3   0.1       0.3   2.7e+03      23      35 ..     207     218 ..     194     226 .. 0.68

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 1.5e-07
                     SSBHHHHHHHHHHHHHHTTCHHHHHHHHTSS-HHHHHHHHHH CS
  Myb_DNA-binding  3 kWteeEdelLleavkkhGnrWkkIaerlggRtekqcrsrwrn 44
                     +WteeE+  L++   +h   +k Ia +l  +te +cr+++++
       EEA21765.1 44 AWTEEEEAYLVRTR-MHKMPYKHIAAHL-KKTELACRLHYHQ 83
                     8*********8864.55567********.7**********87 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.3
                      HHHHHHHHTSS-H CS
  Myb_DNA-binding  23 WkkIaerlggRte 35 
                      W+kI+ ++  R  
       EEA21765.1 207 WSKISTEYS-RDS 218
                      99*998874.444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (310 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       473  (0.0263818); expected 358.6 (0.02)
Passed bias filter:                      290  (0.0161749); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.22s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2347.91
//
Query:       EEA21766.1  [L=238]
Description: MYB DNA-binding domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.7e-15   56.3   3.5    3.3e-09   36.8   0.8    2.3  2  Myb_DNA-binding  Myb-like DNA-binding domain
    1.1e-09   38.4   3.5    1.1e-05   25.6   0.8    2.4  2  Myb_DNA-bind_6   Myb-like DNA-binding domain
  ------ inclusion threshold ------
      0.011   15.8  12.8      0.012   15.7  12.8    1.1  1  TFIIA            Transcription factor IIA, alpha/beta subunit
       0.15   10.7   8.0       0.16   10.6   8.0    1.2  1  Hamartin         Hamartin protein
       0.18   12.4  15.5       0.34   11.6  15.5    1.4  1  Pex14_N          Peroxisomal membrane anchor protein (Pex14p)
       0.51   10.3   4.9      0.068   13.1   0.7    1.8  2  Myb_DNA-bind_7   Myb DNA-binding like
       0.87    8.2   7.5       0.88    8.1   7.5    1.0  1  CCDC14           Coiled-coil domain-containing protein 14


Domain annotation for each model (and alignments):
>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.8   0.8   1.3e-12   3.3e-09       3      44 ..     146     186 ..     144     186 .. 0.94
   2 !   20.1   0.1   2.2e-07   0.00055       4      43 ..     193     232 ..     191     235 .. 0.90

  Alignments for each domain:
  == domain 1  score: 36.8 bits;  conditional E-value: 1.3e-12
                      SSBHHHHHHHHHHHHHHTTCHHHHHHHHTSS-HHHHHHHHHH CS
  Myb_DNA-binding   3 kWteeEdelLleavkkhGnrWkkIaerlggRtekqcrsrwrn 44 
                      +Wt+eE+++L +   + G++W++Ia+ ++ Rte +++ +w++
       EEA21766.1 146 PWTAEEEQRLKQMRDL-GKSWSEIAKTFPARTEGSVKKHWYK 186
                      8***********9866.***********************96 PP

  == domain 2  score: 20.1 bits;  conditional E-value: 2.2e-07
                      SBHHHHHHHHHHHHHHT.TCHHHHHHHHTSS-HHHHHHHHH CS
  Myb_DNA-binding   4 WteeEdelLleavkkhG.nrWkkIaerlggRtekqcrsrwr 43 
                      + e+E   L ea+k++  n+Wk I +++ g+ +k+c  + +
       EEA21766.1 193 FGEDESVALREAIKEYEaNKWKVIGQKI-GKPAKACEQYAK 232
                      77999***********************.6******98865 PP

>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.8   4.1e-09   1.1e-05       1      41 [.     147     186 ..     147     192 .. 0.91
   2 !   13.1   0.1   3.4e-05     0.088       3      38 ..     195     230 ..     193     237 .. 0.88

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 4.1e-09
  Myb_DNA-bind_6   1 WteeEdeiLlklvekygndWknIaealnrRtpkqcfdrwkn 41 
                     Wt+eE+++L k +++ g+ W++Ia+ ++ Rt  +++ +w +
      EEA21766.1 147 WTAEEEQRL-KQMRDLGKSWSEIAKTFPARTEGSVKKHWYK 186
                     ********9.668999***********77**********87 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 3.4e-05
  Myb_DNA-bind_6   3 eeEdeiLlklvekyg.ndWknIaealnrRtpkqcfdr 38 
                     e+E  +L++  ++y+ n+Wk I + ++ + +k+c ++
      EEA21766.1 195 EDESVALREAIKEYEaNKWKVIGQKIG-KPAKACEQY 230
                     689999********879**********.999999875 PP

>> TFIIA  Transcription factor IIA, alpha/beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.7  12.8   4.5e-06     0.012     127     221 ..      13     114 ..       2     232 .. 0.46

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 4.5e-06
       TFIIA 127 qipagvtlqtasgqlykvnvqasgaqqiaaqplqqvvqqsqgsaaqssvaalqaqsqqaqalaepqqqlekqqqq...qqqqqqqqqqqqvqqqqqe.. 220
                 q+pa ++  + s+   +  v+ s++ ++ ++++qq     q++ ++ss+a+++a +  + ++  p+q +  +++q   q qqqqqqqq qv+  +++  
  EEA21766.1  13 QTPALFSMMSSSPM--SKRVKGSAGLNRSSAQQQQ-----QAALSASSLAPPSAYPLTTPTAQTPSQPQP-HHHQlqpQSQQQQQQQQ-QVNPRKRRsp 102
                 55554443333332..2233444444444333333.....466666666666665444444434444321.11111012222222222.2222222122 PP

       TFIIA 221 ...........e 221
                             
  EEA21766.1 103 psattatagisA 114
                 222222222220 PP

>> Hamartin  Hamartin protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   8.0   6.3e-05      0.16     330     417 ..      14     102 ..       3     233 .. 0.65

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 6.3e-05
    Hamartin 330 SPssvcgmttppsspgivpttelelsssasllsskvsstpeaagkatpetTPakssrklppslsesavvvalpassrkss.pprkdeks 417
                  P +++ m+ +p s+++  +  l+ ss+++++++  s  + a   a p tTP ++++++p+++ ++   ++++++ ++++  prk +++
  EEA21766.1  14 TPALFSMMSSSPMSKRVKGSAGLNRSSAQQQQQAALSASSLAPPSAYPLTTPTAQTPSQPQPHHHQLQPQSQQQQQQQQQvNPRKRRSP 102
                 46677777777777776665446555555555555555555555667777777777766555555444444433333333023333222 PP

>> Pex14_N  Peroxisomal membrane anchor protein (Pex14p) conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6  15.5   0.00013      0.34      60     143 ..      39     122 ..      12     128 .. 0.57

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00013
     Pex14_N  60 ssas.eqaqeesasssatpqpqaasqtsqsspspsppaqqqqqqyrpPivtypefltkppkppppPlrtwrdllitatalaglga 143
                 ssa+ +q+++ sass a+p++ + +++++++ps+++p+++q q ++++++++++++++p+k+  pP  t+ ++ i a   +g+ a
  EEA21766.1  39 SSAQqQQQAALSASSLAPPSAYPLTTPTAQTPSQPQPHHHQLQ-PQSQQQQQQQQQVNPRKRRSPPSATTATAGISAIPGSGVVA 122
                 2222123344444444444444444444444444444443333.34666666777788999999999999888888776666655 PP

>> Myb_DNA-bind_7  Myb DNA-binding like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.2       4.2   1.1e+04      78      85 ..      83      90 ..      72      94 .. 0.47
   2 ?   13.1   0.7   2.6e-05     0.068       6      51 ..     142     186 ..     138     222 .. 0.90

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 4.2
  Myb_DNA-bind_7 78 eaekekee 85
                    + ++++++
      EEA21766.1 83 QSQQQQQQ 90
                    33333333 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 2.6e-05
  Myb_DNA-bind_7   6 kktkkWskeetekFYkaLsqfGtDFsliaklfpkrtrrqlKlKFkk 51 
                     +++++W+ ee ++  k ++ +G  +s iak fp rt   +K+ + k
      EEA21766.1 142 RTNTPWTAEEEQRL-KQMRDLGKSWSEIAKTFPARTEGSVKKHWYK 186
                     47789***999996.99************************98765 PP

>> CCDC14  Coiled-coil domain-containing protein 14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   7.5   0.00034      0.88     118     232 ..       7     129 ..       1     217 [. 0.58

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00034
      CCDC14 118 alcehvQTQ..MSLlnalaskkspngipavpchtvsesesqaatasnyrlptstpvlsp..qrsanplvvqsevqtdsenqvasqsgavsvlatasvsr 212
                 ++++h QT    S++++ +  k  +g+     ++++++++ a +as++  p+  p  +p  q ++ p+  + ++q +s++q+++q+++   +   s++ 
  EEA21766.1   7 QISDHRQTPalFSMMSSSPMSKRVKGSAGLNRSSAQQQQQAALSASSLAPPSAYPLTTPtaQTPSQPQPHHHQLQPQSQQQQQQQQQVNPRKRR-SPPS 104
                 6788889853379999999888888888887777666666666666666666666554433677788888888887777776666655444433.3332 PP

      CCDC14 213 a.....svsalpgvqpslaqadksa 232
                 a      +sa pg    ++ +++ +
  EEA21766.1 105 AttataGISAIPGSGVVAPVMSDIS 129
                 2344555555555444444332222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (238 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1463  (0.0815996); expected 358.6 (0.02)
Passed bias filter:                      544  (0.0303419); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 1670.58
//
Query:       EEA21767.1  [L=526]
Description: nucleoside transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.2e-14   51.9  40.4    1.2e-13   50.7  40.4    1.6  1  Transp_cyt_pur  Permease for cytosine/purines, uracil, thiami


Domain annotation for each model (and alignments):
>> Transp_cyt_pur  Permease for cytosine/purines, uracil, thiamine, allantoin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.7  40.4   6.6e-18   1.2e-13       4     427 ..      75     490 ..      72     499 .. 0.71

  Alignments for each domain:
  == domain 1  score: 50.7 bits;  conditional E-value: 6.6e-18
  Transp_cyt_pur   4 eeeR...twkt.lnlfsiWlganlnintwvigalg.lalgLnwwqsvlviivgnligaifvallglaGakyGlpfpilsRasfGirgsllplllr 93 
                     e+eR   tw t l++f +W++ nl  n++++g lg  ++gL++ +s l+ ++g+++g  + a  +  G+  G ++ ++ R+  G + s + +ll 
      EEA21767.1  75 EQERhalTWVTyLQVFLLWVSINLAANNITLGMLGpSVYGLSFLDSSLCSVFGSIVGSLAAAWSATWGPISGNRTLVFGRYAMGWWPSKIIVLLN 169
                     55551114544148899******************899**************************************************9999996 PP

  Transp_cyt_pur  94 vviaivwfgvqawiGsealllmlgkifgkwleiggailgtsltelvtffifwvvslvivllgvskirkffviaal.....lvpvaafgfliwalv 183
                     +v  +++  + +++G++ l+ +                  ++ + v+++i  v++  i  +g++ +  ++ +a l     +  +  + +  + l 
      EEA21767.1 170 IVQMVGYGLIDCVVGGQILSAVSPDY--------------HMSVAVGIVIVAVITWFIATFGIKFFHLYERYAFLpqlivVCILYGVSAKKYDLE 250
                     66666666678888888777665555..............4455555555555555555555555555555443300000333333444455555 PP

  Transp_cyt_pur 184 kaegGpvldkavklgkselflsavagvlagfatlilnapDFtryaktkkssvkiqlvavpllftlllligilvaaaakaaygan.aw......sp 271
                      + +G+ l     ++     ls    +l++ +t++++a+DF +y ++ + +v ++ +++++l  +++++ ++++ +a+ + g++ ++      ++
      EEA21767.1 251 TPSVGDSLT----IAGN--RLSFFSICLSAAITYAPLAADFFVYYPPDTPKVVSFGLTFVGLTLSFTMAFLVGIGLASGIGGDTaYAdaynvgAG 339
                     555555555....2222..24555678888899999999****************9998887666666555555555444333203300001144 PP

  Transp_cyt_pur 272 ldilakfdetagvl..lililvalaqlgvnisanllsagldlaallPkkinikrgsliaavialvivpwkllsssskl..ftaflsllavflspv 362
                       i++ f ++ g++  + ++lval  +  n    ++s+g d++ l   ++ +  +++++ ++ ++ ++  l ++s  +  ft+fl l+++ +  +
      EEA21767.1 340 ALIVEGFNPL-GGFgkFCSVLVALGLI-SNTIPPTYSSGIDFQILGH-YAEMVPRIIWNTIAVIIYTVCALVGQSHLSeiFTNFLALMGYWVAIW 431
                     4577778887.5553355666666544.5666789*******97776.9999999****999999999999999998899*************** PP

  Transp_cyt_pur 363 agviiadyfvvrrgylklaalytrrrgsaYwyrkgvNwravaayivGiaaglvgvagsvgikvvk 427
                      ++++ + ++ rr      a  +    s       + ++a+aa++vG a +++ +a   +i +++
      EEA21767.1 432 FAILLEERYIFRRQTGYNWAAWD--DPSKLP----IGLAAFAAFLVGWAGAVICMAQVWYIGPIA 490
                     *****999999998887777777..566544....888889999988888888877655555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (526 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       936  (0.0522059); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.25s 00:00:00.82 Elapsed: 00:00:00.41
# Mc/sec: 3845.42
//
Query:       EEA21768.1  [L=192]
Description: cytochrome c subunit Vb, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-53  180.0   0.0    1.9e-53  179.6   0.0    1.1  1  COX5B     Cytochrome c oxidase subunit Vb


Domain annotation for each model (and alignments):
>> COX5B  Cytochrome c oxidase subunit Vb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  179.6   0.0   1.1e-57   1.9e-53      11     129 .]      45     164 ..      38     164 .. 0.98

  Alignments for each domain:
  == domain 1  score: 179.6 bits;  conditional E-value: 1.1e-57
       COX5B  11 laevkgeesligpgakegtvPtdleqatGleRlellgkleGidvfdmkPldasrkGtledPilvesydderyvGctGspadshkviWlkvekek.vaRc 108
                  +evk+e++l++ g+k+g+vPtdleqatGleRlellgk+ Gidvfdm+PldasrkGtledPi+v+   de+y+GctG+p dsh v+Wl+v++e+ ++Rc
  EEA21768.1  45 YEEVKTEDDLLPLGGKPGQVPTDLEQATGLERLELLGKMRGIDVFDMRPLDASRKGTLEDPIIVNGAGDEQYAGCTGYPVDSHIVNWLTVSRERpIERC 143
                 589*******************************************************************************************9**** PP

       COX5B 109 aecGsvyklkllgeeedehhh 129
                  ecG+v+kl+++g+++d+h+h
  EEA21768.1 144 LECGNVVKLNYVGPDTDAHAH 164
                 ******************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (192 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       306  (0.0170673); expected 358.6 (0.02)
Passed bias filter:                      281  (0.0156729); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.23s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 1382.60
//
Query:       EEA21769.1  [L=1064]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-05   25.4   0.1    3.1e-05   24.0   0.0    1.8  2  NACHT         NACHT domain
     0.0004   20.7   0.0      0.023   15.0   0.0    2.9  2  AAA_22        AAA domain
    0.00048   20.3   2.0     0.0056   16.9   0.1    2.6  2  SesA          N-terminal domain on NACHT_NTPase and P-loop NT
     0.0012   19.3   0.1     0.0099   16.3   0.0    2.4  2  AAA_16        AAA ATPase domain
     0.0055   17.2   1.6      0.031   14.8   0.0    3.0  4  ABC_tran      ABC transporter
  ------ inclusion threshold ------
      0.024   15.2   0.0       0.07   13.7   0.0    1.8  1  Ank_2         Ankyrin repeats (3 copies)
      0.031   14.8   0.7        0.2   12.2   0.4    2.7  2  HSCB_C        HSCB C-terminal oligomerisation domain
      0.051   13.3   0.4       0.13   12.0   0.4    1.6  1  AAA_29        P-loop containing region of AAA domain
       0.17   11.8   0.3       0.45   10.4   0.0    1.8  2  RsgA_GTPase   RsgA GTPase
       0.86   10.1  12.5       0.24   11.9   0.2    3.3  4  AAA_23        AAA domain
       0.99    9.4   9.8         15    5.6   0.2    2.9  3  Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C
        5.7    7.0   8.1        2.6    8.1   0.0    2.9  3  DUF87         Helicase HerA, central domain


Domain annotation for each model (and alignments):
>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0       6.1   9.1e+03      53      66 ..     172     185 ..     148     211 .. 0.57
   2 !   24.0   0.0   2.1e-08   3.1e-05       5     165 ..     348     540 ..     345     541 .. 0.65

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 6.1
                 -HCHHHCCCCTS-- CS
       NACHT  53 sladllfsqlpepa 66 
                 s+  l+ +  +e++
  EEA21769.1 172 SVESLIQKLIKELS 185
                 33333333333333 PP

  == domain 2  score: 24.0 bits;  conditional E-value: 2.1e-08
                 EEC-TTTCHHHHHHHHHH......HHCTS-SCCCC.-SEEEEEETTTTTTS-......-HCHHHCCCCTS--SSS-C.......CHHHHCCSCCCEE.. CS
       NACHT   5 lqGeaGsGKTtLlqklal......awaegklpqga.fklvFflslrelsrsgna...rsladllfsqlpepaapvse.......vwavllelperlL.. 84 
                 + G+aGsGK+tL++ l++      ++ e+  +++  f  +Ff  +++ ++++ +   rsl   +  q+pe + +v +                   L  
  EEA21769.1 348 ISGKAGSGKSTLMKFLCQnprlrsELEEWAGDKKLvFANFFFWASGDKQQRSLEglyRSLLFEILNQCPEFINEVFPdqwanmkS----------HLtr 436
                 89***********977652222226777777776644444444444444444446666666666666666666665555555440..........3334 PP

                 ..............................EEEE-STT-SS-TCH.........HHHHHCTTTTT--EEEEEEECCCHHHHCTTSSCE..EEEE--TCC CS
       NACHT  85 ..............................lilDglDelvtdlgqkekqpvrtlLselirkkllpeasllltvrpralrdleeqleeaivlevegfses 153
                                               + +DglDe + d         +  L++ ++k    +a +++ +++r   +    + +  ++ +  +++ 
  EEA21769.1 437 wegrpfllselrqamgivtakcnfprhrffFFIDGLDEYEGDSTD------HFELARGLQK-WSFSADIKICTSSRPHTEFLDVFDSNLRMDLHHLTRA 528
                 444444556666666888888888888888**********98888......7778888888.4445566666666666568888888888888888888 PP

                 HHHHHHHHCTTT CS
       NACHT 154 rrkqlvrkyfsd 165
                 ++ +++  +f++
  EEA21769.1 529 DIHRFIVAMFEK 540
                 888888877765 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   1.5e-05     0.023       3      71 ..     341     423 ..     339     500 .. 0.73
   2 ?    2.3   0.0      0.12   1.8e+02      42      91 ..     517     564 ..     484     573 .. 0.80

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.5e-05
      AAA_22   3 ktagilvvtGesGtGKTtllrrlleqldeeakaee...erpevv....fvtlpsst...sskdllrellralglelka.....e 71 
                 ++ gi  + G +G+GK+tl++ l ++   +++ ee     +++v    f+ +++++   s++ l+r ll ++ +++ +      
  EEA21769.1 341 SGGGIYHISGKAGSGKSTLMKFLCQNPRLRSELEEwagD-KKLVfanfFFWASGDKqqrSLEGLYRSLLFEILNQCPEfinevF 423
                 4789999*******************9999999999853.33333665555555556678888888888888877777666662 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.12
      AAA_22  42 vvfvtlpsstsskdllrellralglelkaerlsseellealeqalrarav 91 
                  ++++l ++t ++d+ r ++  ++ e++    ++++++ ++++ ++ ++ 
  EEA21769.1 517 NLRMDLHHLT-RADIHRFIVAMFEKEQNF-DSTNKHCRYMVQNIVNGADG 564
                 4477777777.9*****************.9***********99998776 PP

>> SesA  N-terminal domain on NACHT_NTPase and P-loop NTPases
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.1   3.7e-06    0.0056      32     104 ..      41     114 ..      12     125 .. 0.84
   2 ?    2.0   0.2      0.15   2.2e+02      44      86 ..     143     183 ..     135     217 .. 0.60

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 3.7e-06
        SesA  32 gkrLplvqetLedaksqlesskldedtesa.ikpvlesckekatkleeifekvapapadsrleryrkavrslgk 104
                 ++rL +v + L++++++++++ + ++   + +++++++c e   +l++i+e+++++++++ ++  +++++++++
  EEA21769.1  41 NARLSTVLADLKKVTDAIQHDVKGNSPHLEdLRQLAAGCAELSLELSSILETLKKKEGNKVWRNLQAKWKHMKE 114
                 789****************998887766656*******************************999999888554 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.15
        SesA  44 daksqlesskldedtesaikpvlesckekatkleeifekvapa 86 
                 ++ksql++ +++  + s   ++l++  + a+++e++ +k+ ++
  EEA21769.1 143 SVKSQLDEIQDSGLSLS--AESLDNLTNLAKSVESLIQKLIKE 183
                 45666666666665554..555555555555555555555322 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.1      0.97   1.4e+03      72      91 ..     169     186 ..      86     267 .. 0.57
   2 !   16.3   0.0   6.6e-06    0.0099      10     157 ..     329     485 ..     323     496 .. 0.58

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.97
      AAA_16  72 laqalareellrqlldeaes 91 
                 la+    e+l+++l  e+++
  EEA21769.1 169 LAKSV--ESLIQKLIKELSE 186
                 22222..1333333333333 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 6.6e-06
      AAA_16  10 eqLlsalervrsgrpelvllsGesGvGKsslvrellr..alekd...............ggif.lrgkcdqlesaipysalaqalareellrqllde.. 88 
                 +q+++ +  + ++++++  +sG +G+GKs+l++ l +  +l  +               +++f ++g+ +q          ++ l r +ll ++l++  
  EEA21769.1 329 QQVRRSFLGWLRSGGGIYHISGKAGSGKSTLMKFLCQnpRL--RseleewagdkklvfaNFFFwASGDKQQR--------SLEGLYR-SLLFEILNQcp 416
                 5664444445566669****************999984433..34588889999777744333344444444........4555544.22222222222 PP

      AAA_16  89 .....aesaeleawrekleealaavpelagaea.........srllellkrllallsrderplvlvlDdlqwadeaslqllaa 157
                         ++++  + +l                        s l++++    a++  +++ + +++D l+  + +s + +++
  EEA21769.1 417 efineVFPDQWANMKSHL--------------TrwegrpfllSELRQAMGIVTAKCNFPRHRFFFFIDGLDEYEGDSTDHFEL 485
                 221112222222222222..............122234444477777776666777777778999999999988888877665 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.6       2.4   3.6e+03      78      78 ..     190     190 ..      86     328 .. 0.62
   2 !   14.8   0.0     2e-05     0.031      11      35 ..     343     367 ..     340     377 .. 0.88
   3 ?   -1.8   0.0       2.7     4e+03      25      80 ..     759     841 ..     756     871 .. 0.68
   4 ?   -2.5   0.0       4.6   6.8e+03      23      42 ..     866     886 ..     858     912 .. 0.77

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 2.4
                 H CS
                 x RF
    ABC_tran  78 e 78 
                 +
  EEA21769.1 190 R 190
                 3 PP

  == domain 2  score: 14.8 bits;  conditional E-value: 2e-05
                 TSEEEEEESTTSSHHHHHHHHTTSS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  11 gekvaivGenGaGKStLlkllagll 35 
                 g ++ i G+ G+GKStL+k l+++ 
  EEA21769.1 343 GGIYHISGKAGSGKSTLMKFLCQNP 367
                 67899****************9875 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 2.7
                 HHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH..............................H CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..............................x RF
    ABC_tran  25 StLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren..............................e 80 
                 + L++++++  +  ++++  d+++l+   +++++k +    q+p+ fp+ t  ++                              +
  EEA21769.1 759 TQLISCFSKVFDGVADRV-ADQAPLRF--HKEYDKILNHHRQHPFSFPGETTDNSgviawgqrfssvndyanavagddisylhwaA 841
                 677888888888888888.77778877..888999999999999999999766558888776666655555555554444444442 PP

  == domain 4  score: -2.5 bits;  conditional E-value: 4.6
                 SHHHHHH.HHTTSS--SEEEE CS
                 xxxxxxx.xxxxxxxxxxxxx RF
    ABC_tran  23 GKStLlk.llagllkpteGei 42 
                 G S L++ +++gl++p+ G i
  EEA21769.1 866 GRSLLFSaIILGLYEPARGLI 886
                 778887615689****99988 PP

>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   4.7e-05      0.07      25      81 ..     832     898 ..     816     900 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 4.7e-05
       Ank_2  25 ngktaLhyAakng.nleivklLleh...ad..ndgrtpLhyAarsghleivklLlek....gadinl 81 
                 ++ + Lh+Aa+   ++ iv   l++   ++  +dgr+ L+ A+  g +e ++ L++     ga++n 
  EEA21769.1 832 DDISYLHWAASTSqHEYIVDQVLSNpklVNptDDGRSLLFSAIILGLYEPARGLICDllkyGASPNH 898
                 56788******76255679888887778666699***********9888888777322334787775 PP

>> HSCB_C  HSCB C-terminal oligomerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.4   0.00013       0.2      15      62 ..     147     200 ..     141     203 .. 0.74
   2 ?   -3.4   0.0       9.7   1.4e+04      35      50 ..     589     604 ..     587     615 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00013
                 HHHCG....GGSSSH......HHHHHHHHHHHHHHHHHHHHHHHHHHTT-HHHHHHHH CS
      HSCB_C  15 eleea....eeaadk......eeleelkaeveerieeleaeleeafekkdleaaadll 62 
                 +l+e+                + l +l++ ve+ i++l++el+e+ +++d +++  l+
  EEA21769.1 147 QLDEIqdsgL----SlsaeslDNLTNLAKSVESLIQKLIKELSELVRRNDDKTISSLV 200
                 6777733330....1444445*************************776777766554 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 9.7
                 HHHHHHHHHHHHHHHH CS
      HSCB_C  35 veerieeleaeleeaf 50 
                 +e+r+e +  el+++f
  EEA21769.1 589 LEQRLERMPRELDSLF 604
                 6677777777777777 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.4   8.8e-05      0.13      23      39 ..     343     360 ..     338     363 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 8.8e-05
      AAA_29  23 g.atlltGpsGsGKSTll 39 
                 g ++ ++G+ GsGKSTl+
  EEA21769.1 343 GgIYHISGKAGSGKSTLM 360
                 34889***********97 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.1       3.4     5e+03      57      99 ..     134     175 ..     122     181 .. 0.69
   2 ?   10.4   0.0    0.0003      0.45      43     125 ..     278     369 ..     261     377 .. 0.67

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 3.4
                  GG--HHHHHHHHHHHHHHTTSEEEE--TTTHTTHHHHHHHCTT CS
  RsgA_GTPase  57 Dlleeeeeleelkeelealgyevllvsaktkegleelkellkd 99 
                  +l+ +e+  +++k++l +++ + l +sa++ ++l++l++ +++
   EEA21769.1 134 NLILSEQ-QSSVKSQLDEIQDSGLSLSAESLDNLTNLAKSVES 175
                  4555555.57777777777777788888888888888877665 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.0003
                  HHTT-EEEEEEE-GGG--HHH....HHHHHHHHHHHTTSEEEE--TTTH...TTHHHHHHHCTT..SEEEEECSTTSSHHHHHHHHCTT--- CS
  RsgA_GTPase  43 eekgiepvivlnKiDlleeee....eleelkeelealgyevllvsaktk...egleelkellkd..ktsvlvGqSGvGKStLinallpelel 125
                   e+ i+ ++  n  D  +e++    e+++++e + +++++ +  s +++   +  ++   +l++   +  + G+ G GKStL++ l ++ +l
   EEA21769.1 278 SESSITHHVEANNEDTDSERDeedsEISSTAEVIYSTDISSIEYSREQRsrqQVRRSFLGWLRSggGIYHISGKAGSGKSTLMKFLCQNPRL 369
                  5556666666666666655554556666777777777777777766644111333456667776568999**************99987655 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   1.5     0.032        47     130     183 ..     121     188 ..      16     217 .. 0.57
   2 ?   -1.3   0.6       1.7   2.6e+03      49      97 ..     260     326 ..     250     339 .. 0.45
   3 ?   11.9   0.2   0.00016      0.24      19      40 ..     343     364 ..     334     365 .. 0.89
   4 ?   -3.4   0.0       7.5   1.1e+04      28      48 ..     863     883 ..     862     885 .. 0.82

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.032
      AAA_23 130 i..........ilnlilflgqerfeefelkdkke.........rleelekeleeledekkllekleqekekek 183
                 +          +lnlil  +q++ + ++     +           e+l + ++ ++ +++l++kl++e+++  
  EEA21769.1 121 RlnvyrlqlllRLNLILSEQQSSVKSQL-----DeiqdsglslSAESLDNLTNLAKSVESLIQKLIKELSELV 188
                 1223333333344444444444432222.....1222345555777777777777777777777766555544 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.7
      AAA_23  49 rlsrksgrgfeksdveiesegkvkayveltfenkdgry..................trsiererels 97 
                 r++ +s++++e   ++ +se +    ve + e++d ++                    sie++re +
  EEA21769.1 260 RNDEDSKTSSEAKAISNTSESSITHHVEANNEDTDSERdeedseisstaeviystdISSIEYSREQR 326
                 4444444444555555444444444466665555554333333333333333333333344443333 PP

  == domain 3  score: 11.9 bits;  conditional E-value: 0.00016
      AAA_23  19 kgltlItGpNGaGKTTildAik 40 
                  g++ I+G+ G+GK+T++ +++
  EEA21769.1 343 GGIYHISGKAGSGKSTLMKFLC 364
                 68999***************98 PP

  == domain 4  score: -3.4 bits;  conditional E-value: 7.5
      AAA_23  28 NGaGKTTildAiklaLygetp 48 
                 +  G + ++ Ai l+Ly+ ++
  EEA21769.1 863 TDDGRSLLFSAIILGLYEPAR 883
                 6679999**********9665 PP

>> Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.2      0.01        15      64     123 ..      43     101 ..      29     123 .. 0.48
   2 ?    3.7   6.3     0.038        57      36     118 ..     137     216 ..     118     228 .. 0.52
   3 ?   -2.6   0.0       3.5   5.2e+03      34      61 ..     587     614 ..     557     642 .. 0.65

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.01
  Baculo_PEP_C  64 rldtlltnLtdalnalqdtlrneLtnlnsiltnLlssvtNinstLnnllqalnnldlgal 123
                   rl+t+l+ L++   a+q +++ +   l+ +l +L++  + +   L+++l++l+  + +++
    EEA21769.1  43 RLSTVLADLKKVTDAIQHDVKGNSPHLE-DLRQLAAGCAELSLELSSILETLKKKEGNKV 101
                   3333333333333333333333333332.3444444444444444444444444444444 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.038
  Baculo_PEP_C  36 latlldaietqLnalsedlksllaeldtrldtlltnLtdalnalqdtlrneLtnl.nsiltnLlssvtNinstLnnllqalnnl 118
                   l+++  ++++qL++++++  sl+ae  ++    ltnL +++ +l ++l +eL  l   +     ss+  i  +L+ +l+ ++++
    EEA21769.1 137 LSEQQSSVKSQLDEIQDSGLSLSAESLDN----LTNLAKSVESLIQKLIKELSELvRRNDDKTISSLVEIRGSLSAILSQMEAI 216
                   44455555555555555544444432222....234444444444444444444312333334455555555555555555555 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 3.5
  Baculo_PEP_C  34 aqlatlldaietqLnalsedlksllael 61 
                   a l++ l+ + ++L++l e++ +++  +
    EEA21769.1 587 AHLEQRLERMPRELDSLFERIFNSIDPV 614
                   3344444444444444444443333333 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   1.9      0.18   2.7e+02     118     218 ..     102     194 ..      70     212 .. 0.64
   2 ?   -3.0   0.2       4.1   6.1e+03     133     164 ..     276     307 ..     248     345 .. 0.45
   3 ?    8.1   0.0    0.0017       2.6      28      45 ..     348     365 ..     346     367 .. 0.91

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.18
       DUF87 118 rsvleealdqakakeekeklssdepveklleelkkekeelrklknqaiarlldkledllrkggsfsnsstdliallleklekegkitiidlsgvdelaq 216
                 ++ l+ +++ +   +e+  +  +  v++l+  l      l+ + ++++++++++l++++++g s s++s d++++l +  e+  +  i +ls++  +  
  EEA21769.1 102 WRNLQAKWKHM---KEVPVIEQRLNVYRLQLLL-----RLNLILSEQQSSVKSQLDEIQDSGLSLSAESLDNLTNLAKSVESLIQKLIKELSELVRRND 192
                 22222222222...3444444444444322222.....6888888888888888888888888888888888888888888888888888887655555 PP

       DUF87 217 ql 218
                 ++
  EEA21769.1 193 DK 194
                 55 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 4.1
       DUF87 133 ekeklssdepveklleelkkekeelrklknqa 164
                 +  + s+ + ve  +e++ +e++e++++ +++
  EEA21769.1 276 NTSESSITHHVEANNEDTDSERDEEDSEISST 307
                 22233333333333333333333222222222 PP

  == domain 3  score: 8.1 bits;  conditional E-value: 0.0017
       DUF87  28 ilgsTGsGKSntvavLle 45 
                 i g++GsGKS++++ L++
  EEA21769.1 348 ISGKAGSGKSTLMKFLCQ 365
                 679*************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1064 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1520  (0.0847788); expected 358.6 (0.02)
Passed bias filter:                      902  (0.0503096); expected 358.6 (0.02)
Passed Vit filter:                       124  (0.00691617); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.99u 0.31s 00:00:01.30 Elapsed: 00:00:00.49
# Mc/sec: 6495.22
//
Query:       EEA21770.1  [L=284]
Description: MYB DNA-binding domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.1e-13   49.1   0.0    1.9e-07   31.2   0.0    2.4  2  Myb_DNA-bind_6   Myb-like DNA-binding domain
    5.1e-11   42.6   0.2    7.1e-05   22.9   0.0    2.3  2  Myb_DNA-binding  Myb-like DNA-binding domain


Domain annotation for each model (and alignments):
>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.2   0.0   2.2e-11   1.9e-07       1      46 [.     192     237 ..     192     239 .. 0.94
   2 !   15.5   0.0   1.8e-06     0.016       1      38 [.     241     280 ..     241     280 .. 0.90

  Alignments for each domain:
  == domain 1  score: 31.2 bits;  conditional E-value: 2.2e-11
  Myb_DNA-bind_6   1 WteeEdeiLlklvekygndWknIaealnrRtpkqcfdrwknkLrpk 46 
                     +t+eEd +L++l e+ +  Wk+I++ ++ Rt+ +++ r+++kL++k
      EEA21770.1 192 FTPEEDALLVELKEHKNLTWKQISDFFPGRTSGTLQVRYCTKLKAK 237
                     79*************************55**************986 PP

  == domain 2  score: 15.5 bits;  conditional E-value: 1.8e-06
  Myb_DNA-bind_6   1 WteeEdeiLlklvekygnd.WknIaealn.rRtpkqcfdr 38 
                     Wt+e +++L++  ++y+nd W+ Ia   +   tp +c+++
      EEA21770.1 241 WTDEMVQRLRNAIQDYENDrWRIIAGKVGhGFTPAACREK 280
                     *****************955****9998547999999987 PP

>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.0   7.9e-09   7.1e-05       2      43 ..     190     231 ..     189     234 .. 0.83
   2 !   17.5   0.0   3.8e-07    0.0034       4      42 ..     241     281 ..     239     284 .] 0.93

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 7.9e-09
                      SSSBHHHHHHHHHHHHHHT.TCHHHHHHHHTSS-HHHHHHHHH CS
  Myb_DNA-binding   2 gkWteeEdelLleavkkhG.nrWkkIaerlggRtekqcrsrwr 43 
                       k+t+eEd lL+e+ +      Wk I++ ++gRt    + r+ 
       EEA21770.1 190 LKFTPEEDALLVELKEH-KnLTWKQISDFFPGRTSGTLQVRYC 231
                      69*********998655.4355************998888886 PP

  == domain 2  score: 17.5 bits;  conditional E-value: 3.8e-07
                      SBHHHHHHHHHHHHHHT.TCHHHHHHHHT.SS-HHHHHHHH CS
  Myb_DNA-binding   4 WteeEdelLleavkkhG.nrWkkIaerlg.gRtekqcrsrw 42 
                      Wt e  ++L +a++ +  +rW+ Ia ++g g t+ +cr++ 
       EEA21770.1 241 WTDEMVQRLRNAIQDYEnDRWRIIAGKVGhGFTPAACREKA 281
                      9****************888******************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (284 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       525  (0.0292822); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.24s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2024.52
//
Query:       EEA21771.1  [L=447]
Description: tryptophanyl-tRNA synthetase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.8e-21   75.1   0.0    3.7e-20   72.4   0.0    2.0  1  tRNA-synt_1b  tRNA synthetases class I (W and Y)


Domain annotation for each model (and alignments):
>> tRNA-synt_1b  tRNA synthetases class I (W and Y)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.4   0.0   2.1e-24   3.7e-20       4     290 ..     101     397 ..      98     400 .. 0.81

  Alignments for each domain:
  == domain 1  score: 72.4 bits;  conditional E-value: 2.1e-24
                   S--EEEEEEETSSS.-BGGGHHHHHHHHHHHHTTSEEEEEEEHHHHHTTTTT-SSHHHHHHHHHHHHHH..HHHHHHHTCHTTTEEEEETHHHHTTH CS
  tRNA-synt_1b   4 rplrvysGidPTgk.lHlGylvplkklvelqkaghevffliaDlhAiigdpskaeerklrkreevlena..ikaqlakgldpekaevvlqsewlehl 97 
                   +p+ +y+G  P+++ lHlG+++p+    +lq +  +v ++i     +++d +    +kl  ++++   +   k ++a g+dp+k+ ++ + e++   
    EEA21771.1 101 EPFFMYTGRGPSSDaLHLGHTIPFSFTKWLQ-DVFDVPLVIQ----LTDDEKALFKEKLTFEDTYKFGLqnAKDIIAQGFDPKKTFIFSNLEYMGGP 192
                   68889**************************.5555555542....3444443333333333333222233477*******************9987 PP

                   ..HHHHHHHHHHTTCBHHHHHHHHHCCHHCSSSC--BHHHHHHHHHHHHHHHHTCHS....................EEEEEGGGHHHHHHHHHHHH CS
  tRNA-synt_1b  98 ..elaellrdlgklgslnrmlqfksvkkrleegegislgeftYplLqaaDilllkad....................lvpgGsDQkqnielgrdlar 172
                     + ++ +++l+++++++    f +         + ++g + +p  q+  +++                        l p   DQ+  ++l r+ a 
    EEA21771.1 193 flMNTWEFAKLVTFNQVRGAFGFNE---------STNIGRIMFPSVQCVASFATSFPeiwsdppakertkaiakipvLIPMAIDQDPYFRLVRENAH 280
                   3344555666666666666666666.........557999*******998887665568899*********************************** PP

                   HHHHHSTTSS-EEEEET-BBSTTSSS.BTTCETTCGC-BTTCCHHHHHHHHHH.CHCSTTC..SHHHHHHHHHTHHHCHHHHHHHHCCSEEESSHHH CS
  tRNA-synt_1b 173 rfnkkevfkkpegltvplltgldGek.KmSKSagnsaIfLddekesvkkkiqk.avtdsde..evekllklktelsnelierleavsgkkpkreaee 265
                   r++     +kp  +  ++lt l+G   KmS S++nsaIf++d ++++k ki+k a++  +e  e ++ l + +e++   +++l+++ + ++  ++++
    EEA21771.1 281 RMRFP--SPKPALIHSKFLTALQGAGgKMSASDPNSAIFMSDTPNQIKNKINKhAFSGGREtlEEHRRLGGIPEVDV-AFQYLSYFEEDDE--KLKN 372
                   **765..5777777777*******988************************9835555555999999**********.********99998..9*** PP

                   HHHHHHCCCCHHHHHHHHHHHHHHH CS
  tRNA-synt_1b 266 llaeevtklvhggdlkkalaealne 290
                   ++ +++++++  g+lkk + e +++
    EEA21771.1 373 IEDSYRRGELLTGELKKMAIELIQQ 397
                   *******************998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (447 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       697  (0.0388756); expected 358.6 (0.02)
Passed bias filter:                      458  (0.0255452); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.22s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 3135.42
//
Query:       EEA21772.1  [L=313]
Description: tryptophanyl-tRNA synthetase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.2e-09   35.0   0.0    6.8e-08   32.2   0.0    2.0  1  tRNA-synt_1b  tRNA synthetases class I (W and Y)


Domain annotation for each model (and alignments):
>> tRNA-synt_1b  tRNA synthetases class I (W and Y)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.2   0.0   3.8e-12   6.8e-08       4     206 ..     101     313 .]      98     313 .] 0.77

  Alignments for each domain:
  == domain 1  score: 32.2 bits;  conditional E-value: 3.8e-12
                   S--EEEEEEETSSS.-BGGGHHHHHHHHHHHHTTSEEEEEEEHHHHHTTTTT-SSHHHHHHHHHHHHHH..HHHHHHHTCHTTTEEEEETHHHHTTH CS
  tRNA-synt_1b   4 rplrvysGidPTgk.lHlGylvplkklvelqkaghevffliaDlhAiigdpskaeerklrkreevlena..ikaqlakgldpekaevvlqsewlehl 97 
                   +p+ +y+G  P+++ lHlG+++p+    +lq +  +v ++i     +++d +    +kl  ++++   +   k ++a g+dp+k+ ++ + e++   
    EEA21772.1 101 EPFFMYTGRGPSSDaLHLGHTIPFSFTKWLQ-DVFDVPLVIQ----LTDDEKALFKEKLTFEDTYKFGLqnAKDIIAQGFDPKKTFIFSNLEYMGGP 192
                   68889**************************.5555555542....3444443333333333333222233477*******************9987 PP

                   ..HHHHHHHHHHTTCBHHHHHHHHHCCHHCSSSC--BHHHHHHHHHHHHHHHHTCHS....................EEEEEGGGHHHHHHHHHHHH CS
  tRNA-synt_1b  98 ..elaellrdlgklgslnrmlqfksvkkrleegegislgeftYplLqaaDilllkad....................lvpgGsDQkqnielgrdlar 172
                     + ++ +++l+++++++    f +         + ++g + +p  q+  +++                        l p   DQ+  ++l r+ a 
    EEA21772.1 193 flMNTWEFAKLVTFNQVRGAFGFNE---------STNIGRIMFPSVQCVASFATSFPeiwsdppakertkaiakipvLIPMAIDQDPYFRLVRENAH 280
                   3344555666666666666666666.........557999*******998887665568899*********************************** PP

                   HHHHHSTTSS-EEEEET-BBSTTSSS.BTTCETTC CS
  tRNA-synt_1b 173 rfnkkevfkkpegltvplltgldGek.KmSKSagn 206
                   r++     +kp  +  ++lt l+G   KmS S+++
    EEA21772.1 281 RMRFP--SPKPALIHSKFLTALQGAGgKMSASDPK 313
                   **765..5777777777*******988*****985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (313 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       351  (0.0195772); expected 358.6 (0.02)
Passed bias filter:                      338  (0.0188521); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.21s 00:00:00.68 Elapsed: 00:00:00.38
# Mc/sec: 2438.63
//
Query:       EEA21773.1  [L=2355]
Description: pre-mRNA splicing factor (Prp8), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   5.3e-235  779.6   7.4   5.3e-235  779.6   7.4    1.9  2  PROCN           PROCN (NUC071) domain
   4.2e-127  422.5   1.4   7.4e-127  421.7   1.4    1.4  1  PRP8_domainIV   PRP8 domain IV core
    6.1e-89  296.0   2.0    1.9e-88  294.4   2.0    1.9  1  U6-snRNA_bdg    U6-snRNA interacting domain of PrP8
    1.4e-81  271.8   2.0    4.3e-81  270.2   2.0    1.9  1  PRO8NT          PRO8NT (NUC069), PrP8 N-terminal domain
    2.1e-71  238.3   0.1    5.6e-71  236.9   0.1    1.8  1  U5_2-snRNA_bdg  U5-snRNA binding site 2 of PrP8
    2.2e-48  163.2   0.1    6.5e-48  161.7   0.1    1.9  1  PROCT           PROCT (NUC072) domain
    2.8e-48  162.2   0.3    7.7e-48  160.8   0.3    1.8  1  RRM_4           RNA recognition motif of the spliceosomal PrP


Domain annotation for each model (and alignments):
>> PROCN  PROCN (NUC071) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  779.6   7.4  2.1e-238  5.3e-235       2     407 .]     415     820 ..     414     820 .. 1.00
   2 ?   -1.2   0.2      0.24   6.2e+02     241     308 ..    1113    1185 ..    1109    1190 .. 0.74

  Alignments for each domain:
  == domain 1  score: 779.6 bits;  conditional E-value: 2.1e-238
       PROCN   2 ektkdalsllfapaPfnlrsgktkraedvplikkwykeraekeePvkvrvsyqkllkkyvlnelkkkkkkkkkkkkllkelketkffqktkldwveaGl 100
                 ++t++a++ll+ap Pf +rsg++ ra+dvpl+k+wy e++++ +Pvkvrvsyqkllk+yvlnel+k+k k+++k++ll++lk tkffq+t++dwveaGl
  EEA21773.1 415 SDTASAIALLWAPFPFDRRSGRMVRAQDVPLVKQWYLEHCPQGQPVKVRVSYQKLLKTYVLNELHKTKPKAQNKQNLLRTLKGTKFFQTTTIDWVEAGL 513
                 6899*********************************************************************************************** PP

       PROCN 101 qvvrqgfnmlnllihrksltylhldynfnlkPtktlttkerkksrlGnafhlirellrlvkllvdahvqyrlgkidayqladglqyifnhvgqltGiyr 199
                 qv+rqgfnmlnllihrk+ltylhldynfnlkP+ktlttkerkksr+Gnafhl+re+lrl+kl+vda+vqyrlg+ida+qladg+ y fnhvgqltG+yr
  EEA21773.1 514 QVCRQGFNMLNLLIHRKNLTYLHLDYNFNLKPVKTLTTKERKKSRFGNAFHLMREILRLTKLIVDAQVQYRLGNIDAFQLADGILYAFNHVGQLTGMYR 612
                 *************************************************************************************************** PP

       PROCN 200 ykykvmrqirackdlkhviysrfntgevgkGPGvGfwaPswrvwvfflrGiiPllerwlgnllarqfeGrkskevaktitkqrveseydlelraavlhd 298
                 ykyk+m+qir ckdlkh+iy+rfn+g vgkGPG+GfwaP+wrvw+ff+rGiiPllerwlgnll+rqfeGr+sk vakt+tkqrves++dlelra+v+ d
  EEA21773.1 613 YKYKLMHQIRSCKDLKHLIYYRFNSGPVGKGPGCGFWAPAWRVWLFFMRGIIPLLERWLGNLLSRQFEGRHSKGVAKTVTKQRVESHFDLELRASVMAD 711
                 *************************************************************************************************** PP

       PROCN 299 ildmlPegvkqskaktilqhlseafrcwkanipwkvPglpepienlilryvkakadewisvahynrerikrgatvdktvvkknlGrltrlylkeeqerq 397
                 + dm+Peg+kq+k++t+lqhlsea+rcwk+nipwkvPglp+pien+ilryvkakad+wisvahynreri+rgatvdktv+kknlGrltrl+lk+eqerq
  EEA21773.1 712 LIDMMPEGIKQNKVNTVLQHLSEAWRCWKSNIPWKVPGLPAPIENIILRYVKAKADWWISVAHYNRERIRRGATVDKTVAKKNLGRLTRLWLKAEQERQ 810
                 *************************************************************************************************** PP

       PROCN 398 aeylkdgpyi 407
                 ++ylkdgpy+
  EEA21773.1 811 HNYLKDGPYV 820
                 ********97 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.24
       PROCN  241 rvwvfflr...GiiPllerwlgnllarqfe...GrkskevaktitkqrveseydlelraavlhdildmlPegvk 308 
                  ++wvf+         l++r+l++  + +fe   G k+k+   + ++ r   ++d++l  av  d+++ lP  + 
  EEA21773.1 1113 KIWVFLRFsadESRDLIQRFLTEQPDPNFEnviGYKNKKCWPRDSRMRL-MRHDVNLGRAVFWDLKNRLPRSIT 1185
                  67876532111356799******99999993334466666666677776.467*****************9885 PP

>> PRP8_domainIV  PRP8 domain IV core
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  421.7   1.4  2.9e-130  7.4e-127       3     230 .]    1781    2008 ..    1779    2008 .. 0.99

  Alignments for each domain:
  == domain 1  score: 421.7 bits;  conditional E-value: 2.9e-130
  PRP8_domainIV    3 llnsqnyaelfsneiklfvddtnvyrvtvhktfeGnlttkpvnGavfilnPktGqlflkvihtsvwagqkrlsqlakwkaaeevaalvrslPve 96  
                     +lnsqny+elfs +i+lf+ddtnvyrvt+hktfeGnlttkp+nGa+fi+nP+tGqlflk+ihtsvwagqkrl+qlakwk+aeevaal+rslPve
     EEA21773.1 1781 FLNSQNYSELFSPQIQLFIDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVE 1874
                     8********************************************************************************************* PP

  PRP8_domainIV   97 eqPkqiivtrkglldplevhlldfPnivikgselkLPfkavlkiekladlvlkatepkmvlfnlyddWlesissytafsrlililralkinkek 190 
                     eqPkq+ivtrkglldplevhlldfPni+i++sel+LPf+a++k+eklad++l+atep+mvlfnlyd+Wl+sis+ytafsrlililral++n++k
     EEA21773.1 1875 EQPKQLIVTRKGLLDPLEVHLLDFPNISIRASELQLPFQAAMKVEKLADMILRATEPQMVLFNLYDEWLKSISPYTAFSRLILILRALHVNTDK 1968
                     ********************************************************************************************** PP

  PRP8_domainIV  191 akkilkpdkevvvkehhlwptlsdeeWvevevklrdlila 230 
                     +k il+pdk+v+++ehh+wptlsd++W++vev+lrdlil+
     EEA21773.1 1969 TKIILRPDKTVITQEHHIWPTLSDDDWIKVEVQLRDLILN 2008
                     **************************************96 PP

>> U6-snRNA_bdg  U6-snRNA interacting domain of PrP8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  294.4   2.0   7.5e-92   1.9e-88       1     159 []    1461    1619 ..    1461    1619 .. 0.99

  Alignments for each domain:
  == domain 1  score: 294.4 bits;  conditional E-value: 7.5e-92
  U6-snRNA_bdg    1 fkkyqllksekfawtsarhdgkllnleryradviealGgveailehtlfkatsfksweglvwdkasgfeeslkakkltnaqrsGlsqiPnrrftl 95  
                    fk yq++ks++f+wts+rhdgkl+nl++yr+dvi+alGgve+ilehtlfkat f+swegl+w++asgfees+k kkltnaqrsGl+qiPnrrftl
    EEA21773.1 1461 FKIYQIMKSNPFWWTSQRHDGKLWNLNAYRTDVIQALGGVETILEHTLFKATAFPSWEGLFWERASGFEESMKFKKLTNAQRSGLNQIPNRRFTL 1555
                    789******************************************************************************************** PP

  U6-snRNA_bdg   96 WWsPtinranvyvGfqvqldltGvfmhgklptlkisliqifrahlWqkihesvvmdllqvldde 159 
                    WWsPtinranvyvGfqvqldltG+f+hgk+ptlkisliqifrahlWqkihesvvmdl+qv+d+e
    EEA21773.1 1556 WWSPTINRANVYVGFQVQLDLTGIFLHGKIPTLKISLIQIFRAHLWQKIHESVVMDLCQVFDQE 1619
                    **************************************************************96 PP

>> PRO8NT  PRO8NT (NUC069), PrP8 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  270.2   2.0   1.7e-84   4.3e-81       1     152 []      68     219 ..      68     219 .. 0.99

  Alignments for each domain:
  == domain 1  score: 270.2 bits;  conditional E-value: 1.7e-84
                 -----HHHHHHHHHHHTTT-SGGGTTTHHHHHHHHTTSHHHHHHHHTT---TT-S--B--EEEETTT--EEE-----B-HHHHHHHHHHHHHHHHHHHH CS
      PRO8NT   1 keelPpehlRkiikdhgdlsskkfksdkrvylgalkylPhavlkllenmpmpweevrevkvlyhvtgaitfvneiprviepvylaqwstmwiamrrekr 99 
                 k+++PpehlRki+kd gd+s+kkf+sdkr+ylgalk++Phavlkllenmpmpwe++revkvlyhv+g++t+vneiprviepv++aqw+tmw+ mrrek 
  EEA21773.1  68 KTDMPPEHLRKIVKDIGDVSQKKFSSDKRSYLGALKFMPHAVLKLLENMPMPWESAREVKVLYHVNGCLTLVNEIPRVIEPVFHAQWATMWVCMRREKA 166
                 789************************************************************************************************ PP

                 TTS------SS-S-SSS----H.HHHHHH-----------TTTSTTTTTTTT- CS
      PRO8NT 100 drrhfkrlrfppfddeeppldyadnildvepleaiqleldeeedeavvdwlyd 152
                 drrhfkr+rfppfddeeppl++++ni+dveple+iq+elde ed+av++w+yd
  EEA21773.1 167 DRRHFKRMRFPPFDDEEPPLSWSENIEDVEPLEPIQMELDEIEDAAVYEWFYD 219
                 ****************************************************9 PP

>> U5_2-snRNA_bdg  U5-snRNA binding site 2 of PrP8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  236.9   0.1   2.2e-74   5.6e-71       1     134 []    1229    1362 ..    1229    1362 .. 0.99

  Alignments for each domain:
  == domain 1  score: 236.9 bits;  conditional E-value: 2.2e-74
  U5_2-snRNA_bdg    1 kegvwdlvnestkertakaflkvseeeiekfenrirqillssgsttftkiaakwntalialltyfreavvsteelldvlvkaetkiqtrvklg 93  
                      k++vw+lv+++tkerta afl+v+ee+i+kf+nrirqil+ssgsttftkia+kwntalial+ty+rea+vst +lld++vk+etkiqtrvk+g
      EEA21773.1 1229 KDSVWSLVDNTTKERTAYAFLQVTEEDIQKFNNRIRQILMSSGSTTFTKIANKWNTALIALFTYYREAAVSTVNLLDTIVKCETKIQTRVKIG 1321
                      689****************************************************************************************** PP

  U5_2-snRNA_bdg   94 lnskmpsrfPpavfytPkelGGlGmlsaghvliPasdlkys 134 
                      lnskmpsrfPpavfytPkelGGlGm+s +h+liPasd ++s
      EEA21773.1 1322 LNSKMPSRFPPAVFYTPKELGGLGMISGSHILIPASDKRWS 1362
                      ****************************************8 PP

>> PROCT  PROCT (NUC072) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  161.7   0.1   2.5e-51   6.5e-48       1     122 [.    2232    2352 ..    2232    2353 .. 0.96

  Alignments for each domain:
  == domain 1  score: 161.7 bits;  conditional E-value: 2.5e-51
       PROCT    1 ivltvsftpgsvslsayklteeGyewgkknkdlasenpegfepsfsekvqllLsdrilGfflvPeegvWnysfmgakfs..ekmkyelkldiPkeFy 95  
                  +++tvsftpgsvsl+a++lt++Gy+wg++nkd++s++p+gf++s+ +k+qllLsd+i+G+flvPe++vWnysfmg++fs  ek  + +k+d+P++Fy
  EEA21773.1 2232 VTMTVSFTPGSVSLAAWALTPQGYKWGAENKDTSSDQPQGFSTSMGDKCQLLLSDKIRGYFLVPEDNVWNYSFMGSSFSsvEKRPVYVKIDTPLRFY 2328
                  79****************************************************************************9888999************ PP

       PROCT   96 delHRpthFlqfaeleeeeeleadqed 122 
                  d++HRp hF++fael   e+ ++d++d
  EEA21773.1 2329 DDQHRPLHFQNFAEL---EDIWVDRSD 2352
                  ***************...457777766 PP

>> RRM_4  RNA recognition motif of the spliceosomal PrP8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  160.8   0.3     3e-51   7.7e-48       1      91 [.    1005    1095 ..    1005    1096 .. 0.99

  Alignments for each domain:
  == domain 1  score: 160.8 bits;  conditional E-value: 3e-51
       RRM_4    1 ekidltllnrllrlivdknladyitaknnvvltykdmshvnsyGlirGlqfssfvvqyyglvldllllGleraselaGpaekpneflqfkd 91  
                  ekidltllnrllrli+d+nladyit+knnv+l+ykdm+h+nsyGlirGlqfs+fv+qyyglv+dllllGl+ra+elaGp+++pn+flqfkd
  EEA21773.1 1005 EKIDLTLLNRLLRLIMDHNLADYITSKNNVQLNYKDMNHTNSYGLIRGLQFSGFVFQYYGLVIDLLLLGLQRATELAGPPQSPNDFLQFKD 1095
                  89***************************************************************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2355 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       761  (0.0424452); expected 358.6 (0.02)
Passed bias filter:                      498  (0.0277762); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 1.05u 0.33s 00:00:01.38 Elapsed: 00:00:00.52
# Mc/sec: 13575.88
//
Query:       EEA21774.1  [L=120]
Description: ribosomal protein L34 protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      9e-43  144.5   2.7    1.3e-42  143.9   2.7    1.3  1  Ribosomal_L34e  Ribosomal protein L34e
  ------ inclusion threshold ------
      0.031   13.7   0.9      0.062   12.7   0.0    2.0  2  Vps36-NZF-N     Vacuolar protein sorting 36 NZF-N zinc-finger
       0.81    9.7   4.9        3.5    7.7   0.3    2.7  2  FhuF_C          FhuF 2Fe-2S C-terminal domain


Domain annotation for each model (and alignments):
>> Ribosomal_L34e  Ribosomal protein L34e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  143.9   2.7   2.3e-46   1.3e-42       1      94 []       1      95 [.       1      95 [. 0.98

  Alignments for each domain:
  == domain 1  score: 143.9 bits;  conditional E-value: 2.3e-46
  Ribosomal_L34e  1 Mv.qrltyrrrlsYntrsnkvrvvktpggklvyqykkkkgkapkCgdckkkLqGipalrpkelsrlsktkktvsRaYGgslcakcvkerivrafl 94
                    M+ +rl+yrrr+ Yntrsn+vr++ktpgg+l+y+++kkkg+apkCgdc+ kL G+palrp+e++++s+ +k+vsRaYGgs+c++cvk+rivrafl
      EEA21774.1  1 MAnTRLQYRRRNPYNTRSNRVRIIKTPGGNLRYLHIKKKGTAPKCGDCGVKLPGVPALRPREYAQISRPRKNVSRAYGGSRCGNCVKDRIVRAFL 95
                    66579*****************************************************************************************8 PP

>> Vps36-NZF-N  Vacuolar protein sorting 36 NZF-N zinc-finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0     1e-05     0.062      28      44 ..      37      53 ..      18      73 .. 0.82
   2 ?   -1.4   0.2      0.25   1.5e+03      46      62 ..     100     116 ..      97     119 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 1e-05
  Vps36-NZF-N 28 nastplPpClaCGvkpd 44
                 +++ + P+C  CGvk +
   EEA21774.1 37 KKKGTAPKCGDCGVKLP 53
                 678899*********87 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.25
  Vps36-NZF-N  46 elikksikasasskkse 62 
                  +++kk +k s++++k++
   EEA21774.1 100 KIVKKVLKESQEKEKAA 116
                  57888888888887765 PP

>> FhuF_C  FhuF 2Fe-2S C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.5     0.016        93      14      19 ..      43      48 ..      39      48 .. 0.88
   2 ?    7.7   0.3   0.00058       3.5      12      21 .]      78      87 ..      76      87 .. 0.89

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.016
      FhuF_C 14 eyCgsC 19
                ++Cg+C
  EEA21774.1 43 PKCGDC 48
                68**** PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.00058
      FhuF_C 12 ggeyCgsCPL 21
                gg +Cg+C++
  EEA21774.1 78 GGSRCGNCVK 87
                7899****96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (120 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       813  (0.0453455); expected 358.6 (0.02)
Passed bias filter:                      429  (0.0239277); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.39u 0.24s 00:00:00.63 Elapsed: 00:00:00.40
# Mc/sec: 901.07
//
Query:       EEA21775.1  [L=86]
Description: ribosomal protein L34 protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.8e-16   59.6   0.1      5e-16   58.8   0.1    1.4  1  Ribosomal_L34e  Ribosomal protein L34e


Domain annotation for each model (and alignments):
>> Ribosomal_L34e  Ribosomal protein L34e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.8   0.1   2.8e-20     5e-16      52      94 .]      19      61 ..       9      61 .. 0.94

  Alignments for each domain:
  == domain 1  score: 58.8 bits;  conditional E-value: 2.8e-20
  Ribosomal_L34e 52 qGipalrpkelsrlsktkktvsRaYGgslcakcvkerivrafl 94
                    + +palrp+e++++s+ +k+vsRaYGgs+c++cvk+rivrafl
      EEA21775.1 19 NQVPALRPREYAQISRPRKNVSRAYGGSRCGNCVKDRIVRAFL 61
                    679***************************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (86 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       780  (0.0435049); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.28s 00:00:00.66 Elapsed: 00:00:00.44
# Mc/sec: 583.10
//
Query:       EEA21776.1  [L=451]
Description: forkhead domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-20   72.1   0.3      7e-20   71.1   0.3    1.5  1  Forkhead  Forkhead domain
  ------ inclusion threshold ------
       0.54    9.9   2.0          1    9.0   2.0    1.4  1  DUF4712   Domain of unknown function (DUF4712)


Domain annotation for each model (and alignments):
>> Forkhead  Forkhead domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.1   0.3   7.9e-24     7e-20       6      83 ..     234     313 ..     232     317 .. 0.90

  Alignments for each domain:
  == domain 1  score: 71.1 bits;  conditional E-value: 7.9e-24
                 -HHHHHHHHHHT-TTT-B-HHHHHHHHHCC-HHHHCC.-CCHHHHHHHHHHHHC--EEETT..-T.TSS--EEE--TTHH CS
    Forkhead   6 sYaaLIaqAiksspekkltLseIyefieenfpyyrtaakkgWqnSirhnLslnkcFekvpr.eee.egkgslwtidpese 83 
                  Ya L ++A++s++++k++L+eIy+++e+n +   + ++kgWq+SirhnLs+n++F+  ++ + + ++k+s+wt+++e+ 
  EEA21776.1 234 PYAYLLYEALRSAKDHKMSLQEIYRWFEDNTNKAGDPRSKGWQSSIRHNLSMNEAFILHNEyPARgKSKNSYWTLTEEAL 313
                 49**********************************99********************9973443357********9865 PP

>> DUF4712  Domain of unknown function (DUF4712)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   2.0   0.00012         1      27     103 ..     125     208 ..     116     225 .. 0.75

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00012
     DUF4712  27 qecsgqqkleadasPssaakavsrLlcrRtP.laasssaa.....plas.vpcapenenpvFapnhipvnvkpnalspkRkPls 103
                 q++  ++++ a  sP    ++ ++LlcrRtP l+ +s +      p+ s  p +p  +n   ++n +p+n   +  sp R  l+
  EEA21776.1 125 QNSFFNPNIVAYESPLLQDNSDQSLLCRRTPtLNRESHTPsyvqtPYGSrFPPTPRMQNRELVTNSVPINNPREDTSPVRLSLA 208
                 4444577888899******************75555544433344543325667999999999999999999888888887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (451 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       375  (0.0209158); expected 358.6 (0.02)
Passed bias filter:                      271  (0.0151152); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 3123.19
//
Query:       EEA21777.1  [L=544]
Description: cactin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.8e-64  215.2   5.8    1.3e-63  214.4   5.8    1.5  1  Cactin_mid      Conserved mid region of cactin
      2e-57  192.5   6.6    3.6e-57  191.7   6.6    1.4  1  CactinC_cactus  Cactus-binding C-terminus of cactin protein
  ------ inclusion threshold ------
      0.013   15.9   0.0      0.054   13.9   0.0    2.1  1  SF3A2           Pre-mRNA-splicing factor SF3a complex subunit
      0.032   14.2   0.9      0.091   12.8   0.2    2.1  2  DUF1087         Domain of Unknown Function (DUF1087)


Domain annotation for each model (and alignments):
>> Cactin_mid  Conserved mid region of cactin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  214.4   5.8   2.8e-67   1.3e-63       2     197 ..      62     246 ..      61     247 .. 0.97

  Alignments for each domain:
  == domain 1  score: 214.4 bits;  conditional E-value: 2.8e-67
  Cactin_mid   2 ekeeeqyeeweakEeeFhleqakkraeiRikegrakpiDlLaknlrlvdeeedeedde.adleieleePykileglsleeleeleediksyleleksek 99 
                  +e+eq++ew+a+E+ F+l+qakk+aeiR+kegrakpiD+La++lr++d+++++ dde +d +++l +P+ ++egls+++l ele+di+++l+le+s+k
  EEA21777.1  62 LQEDEQVREWVAQEDVFVLKQAKKKAEIRVKEGRAKPIDWLAVTLRIIDPTRNPLDDEiSDSDLDLIDPEGVFEGLSQAQLVELEKDIDTFLSLEQSQK 160
                 689****************************************************999*99************************************** PP

  Cactin_mid 100 naefWkallvvckdeleklkkkeeekeaaeeaeesgihasveadikkilkgksleeLeelekqikekLesgeavDveYWesllkklkvykAkarLkdi 197
                 n++fWk+++vvc+d+ +             +a e+++ +sv+adi+kil++k++e+Le+le q+++kL+s+e++D++YWe+ll++l v+kA+a+Lk++
  EEA21777.1 161 NRDFWKTMKVVCRDRQKI------------SAPEGRVLSSVAADINKILSPKTYEQLETLEVQVRRKLDSNEPIDTDYWEELLRSLTVWKARAKLKKV 246
                 **************9988............35789************************************************************986 PP

>> CactinC_cactus  Cactus-binding C-terminus of cactin protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  191.7   6.6     8e-61   3.6e-57       1     125 []     407     544 .]     407     544 .] 0.98

  Alignments for each domain:
  == domain 1  score: 191.7 bits;  conditional E-value: 8e-61
  CactinC_cactus   1 wedkyelrkPkyfnrvktgyeWnkynkthydednpPPkvvqgykFnifypdLidkekaptykiekk...........teeeetvllrfkagkpYe 84 
                     w++ky++rkP+yfnrv++gyeWnkyn+thyd+d+pPPkvv+gy+FnifypdLidk+kapty+ie++           + ee+t+l+rf ag+pYe
      EEA21777.1 407 WANKYRPRKPRYFNRVQMGYEWNKYNQTHYDHDHPPPKVVHGYRFNIFYPDLIDKTKAPTYRIEREhgrkrgqsfvkAGEEDTCLIRFIAGPPYE 501
                     99*************************************************************************9988899************* PP

  CactinC_cactus  85 diafrivdkewdlskk..rgfkssfergvlqlyfnfkkskyrr 125
                     diafrivd+ewd+s+k  rgfkssfe+g+lql+f+fkk  yr+
      EEA21777.1 502 DIAFRIVDREWDYSAKrdRGFKSSFEKGILQLHFQFKKIYYRK 544
                     *************998779**********************97 PP

>> SF3A2  Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   1.2e-05     0.054      19      81 ..     447     515 ..     429     529 .. 0.72

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.2e-05
       SF3A2  19 vgllvevkypeike.evkPlhrimsale....qk.leekpdkkvqyLliaaePYetiafkipskeidks 81 
                 +g  +++ yp+  + +++P +ri  +      q+ +++ +++ +    ia  PYe iaf+i ++e d s
  EEA21777.1 447 HGYRFNIFYPDLIDkTKAPTYRIEREHGrkrgQSfVKAGEEDTCLIRFIAGPPYEDIAFRIVDREWDYS 515
                 68889999*987774667*****9888833333212223345555557*************99987655 PP

>> DUF1087  Domain of Unknown Function (DUF1087)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0       2.5   1.1e+04      15      25 ..     156     166 ..     145     168 .. 0.71
   2 ?   12.8   0.2     2e-05     0.091      12      29 ..     213     232 ..     203     234 .. 0.72

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 2.5
     DUF1087  15 enesedpdYWe 25 
                 e+++++ d+W+
  EEA21777.1 156 EQSQKNRDFWK 166
                 56778889997 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 2e-05
     DUF1087  12 ikq..enesedpdYWekLLr 29 
                  ++  +ne  d+dYWe+LLr
  EEA21777.1 213 RRKldSNEPIDTDYWEELLR 232
                 3334369999*********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (544 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       755  (0.0421105); expected 358.6 (0.02)
Passed bias filter:                      353  (0.0196888); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.47
# Mc/sec: 3467.64
//
Query:       EEA21778.1  [L=593]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-43  149.2   0.7    1.4e-43  149.2   0.7    1.8  2  XLF       XLF-Cernunnos, XRcc4-like factor, NHEJ component


Domain annotation for each model (and alignments):
>> XLF  XLF-Cernunnos, XRcc4-like factor, NHEJ component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  149.2   0.7   7.6e-48   1.4e-43       2     169 ..       5     169 ..       4     175 .. 0.95
   2 ?   -2.6   0.4      0.29   5.1e+03     137     157 ..     562     582 ..     560     585 .. 0.79

  Alignments for each domain:
  == domain 1  score: 149.2 bits;  conditional E-value: 7.6e-48
         XLF   2 Wrvleidgse.pkllvklefsessyellltDlanvWseeldrdeilkrakeentsidpsedeeqlavlleklrkaldgskkssaefslnlsskaeedsL 99 
                 W++l+  + + p ll+++  +++sye+ ltDl+++W+e+l  +++l++a++  tsidpsed+ q+ v++ k+++aldg++++     +++ s  ++ds 
  EEA21778.1   5 WHSLPTRNISaPLLLYSFIYTSQSYEFFLTDLTHIWHENLQYKHVLQKAEDIGTSIDPSEDANQYDVFMRKIQDALDGANNT----GVTIASGHKSDSV 99 
                 *****998667*****************************************************************999999....67777767789** PP

         XLF 100 tlkltieLpgplspleWefslvkepsssltkeLvlpllqasaelkrqveeLieilkeKDavIskLldkle 169
                  ++++++Lp++l+pl+W+f+l+kep+s++t++L+lpll++++++++++++L+e ++eKD+++sk++dk+ 
  EEA21778.1 100 VVTTSTKLPAGLNPLKWTFTLSKEPPSAVTRHLLLPLLKSERNHEQREQSLLEHIREKDNILSKIFDKID 169
                 *******************************************************************986 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 0.29
         XLF 137 lqasaelkrqveeLieilkeK 157
                 l+a++  +++ eeL ++l +K
  EEA21778.1 562 LSAEQKANKKREELKRQLDAK 582
                 567788899999999999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (593 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1009  (0.0562775); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.30s 00:00:00.95 Elapsed: 00:00:00.47
# Mc/sec: 3768.45
//
Query:       EEA21779.1  [L=1347]
Description: WD repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.6e-15   57.2  10.2    2.1e-06   28.3   0.1    5.9  6  WD40          WD domain, G-beta repeat
    2.8e-06   27.5   0.1        1.1    9.6   0.0    4.6  5  ANAPC4_WD40   Anaphase-promoting complex subunit 4 WD40 domai
    8.3e-06   25.8   0.1     0.0042   17.0   0.0    3.2  3  eIF2A         Eukaryotic translation initiation factor eIF2A
  ------ inclusion threshold ------
      0.038   13.6   9.0      0.089   12.4   9.0    1.6  1  Zn_ribbon_17  Zinc-ribbon, C4HC2 type
      0.079   13.1   0.2       0.18   12.0   0.2    1.5  1  HSP20         Hsp20/alpha crystallin family
        3.2    8.1   9.3       0.12   12.7   0.7    2.5  2  zf-rbx1       RING-H2 zinc finger domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.0         6   1.8e+04       9      26 ..      98     118 ..      94     122 .. 0.65
   2 !   21.9   0.0   7.4e-08   0.00022       5      38 .]     204     239 ..     200     239 .. 0.83
   3 ?    1.8   0.7      0.17   5.1e+02       7      38 .]     255     288 ..     249     288 .. 0.63
   4 !   28.3   0.1   7.1e-10   2.1e-06       3      38 .]     295     331 ..     293     331 .. 0.91
   5 !    6.2   0.0    0.0071        21      17      38 .]     364     392 ..     341     392 .. 0.79
   6 ?   -1.1   0.0       1.4   4.3e+03      14      27 ..     448     461 ..     445     465 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 6
                 SS.SS..EEEEEEETTSSEEE CS
        WD40   9 GH.ss..vtslafspdgawla 26 
                 +H ++  + +l+ sp ++  +
  EEA21779.1  98 THrTGvsIAALDISPQKTHAV 118
                 476554467888999888743 PP

  == domain 2  score: 21.9 bits;  conditional E-value: 7.4e-08
                 EEEESSSS.EEEEE.EETTSSEEEEEETTSEEEEEE CS
        WD40   5 rtltGHss.vtsla.fspdgawlasGsdDgtvriWd 38 
                   l+GHs  v+ la +++  awl+sGs D t+r+Wd
  EEA21779.1 204 SRLSGHSRqVHKLAfNPHRPAWLLSGSQDSTIRMWD 239
                 5689**557*****66666777*************9 PP

  == domain 3  score: 1.8 bits;  conditional E-value: 0.17
                 EESSSS.EEEEE.EETTSSEEEEEETTSEEEEEE CS
        WD40   7 ltGHss.vtsla.fspdgawlasGsdDgtvriWd 38 
                 ++  s+ v++++    dg+ +a+++d g +  Wd
  EEA21779.1 255 YSSNSDaVRDIRwSTGDGTVFATATDSGAIQCWD 288
                 6666445999973334444457888888888887 PP

  == domain 4  score: 28.3 bits;  conditional E-value: 7.1e-10
                 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 ++ ++t+H ++ ++++++pdg+ l+s++ D+ v++Wd
  EEA21779.1 295 PQLKITAHeKPCYAVDWHPDGKHLVSAGTDRQVKVWD 331
                 566789**99***************9888*******9 PP

  == domain 5  score: 6.2 bits;  conditional E-value: 0.0071
                 E.EETTSSE....EEEEET..TSEEEEEE CS
        WD40  17 a.fspdgaw....lasGsd..DgtvriWd 38 
                 + fs+d +w    ++++ d  D+ v++Wd
  EEA21779.1 364 SeFSDDRNWqstqVVTSYDkeDPRVHLWD 392
                 26999*******999997566*******9 PP

  == domain 6  score: -1.1 bits;  conditional E-value: 1.4
                 EEEEEETTSSEEEE CS
        WD40  14 tslafspdgawlas 27 
                 +++a+sp g  +a+
  EEA21779.1 448 CAVAWSPTGEVVAT 461
                 689******99876 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0     0.016        48      33      89 ..     160     218 ..     145     221 .. 0.71
   2 ?    1.5   0.0      0.12   3.6e+02      37      77 ..     209     250 ..     202     257 .. 0.82
   3 !    6.7   0.0    0.0029       8.7      35      71 ..     256     293 ..     247     305 .. 0.82
   4 !    9.6   0.0   0.00037       1.1      38      74 ..     303     339 ..     296     359 .. 0.74
   5 ?   -2.2   0.0       1.8   5.3e+03      43      56 ..     449     462 ..     439     466 .. 0.74

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.016
  ANAPC4_WD40  33 eedkedsevrsLaWkpd..gklLavaysdgevrlldaesgkv.vhslsvksekavtclgW 89 
                  ++ k++  +++++W++   ++++a a ++g++  +d + + + ++ ls +s  +v +l +
   EEA21779.1 160 SKFKDQLAIKDVKWSHGefDTVIATAAANGRIITYDLQRAGLeLSRLSGHSR-QVHKLAF 218
                  45578899******9863369**************99876541444444444.4666665 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.12
  ANAPC4_WD40  37 edsevrsLaWkpdg.klLavaysdgevrlldaesgkvvhsls 77 
                  ++++v++La++p     L  + +d+++r+ d  s+    +++
   EEA21779.1 209 HSRQVHKLAFNPHRpAWLLSGSQDSTIRMWDLRSASPAATIQ 250
                  678999****997527899************99988776665 PP

  == domain 3  score: 6.7 bits;  conditional E-value: 0.0029
  ANAPC4_WD40  35 dkedsevrsLaWk.pdgklLavaysdgevrlldaesgk 71 
                  ++++  vr+++W+  dg+++a a++ g+++  d  ++k
   EEA21779.1 256 SSNSDAVRDIRWStGDGTVFATATDSGAIQCWDYRQTK 293
                  467789******8369**************99988776 PP

  == domain 4  score: 9.6 bits;  conditional E-value: 0.00037
  ANAPC4_WD40  38 dsevrsLaWkpdgklLavaysdgevrlldaesgkvvh 74 
                  ++   ++ W+pdgk L+ a  d +v++ d +s    +
   EEA21779.1 303 EKPCYAVDWHPDGKHLVSAGTDRQVKVWDFSSSAERR 339
                  56667899*******************9988765544 PP

  == domain 5  score: -2.2 bits;  conditional E-value: 1.8
  ANAPC4_WD40  43 sLaWkpdgklLava 56 
                  ++aW+p g++ a +
   EEA21779.1 449 AVAWSPTGEVVATV 462
                  57788888887765 PP

>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.4   0.0    0.0024       7.2      57     162 ..     163     279 ..     151     281 .. 0.73
   2 !   17.0   0.0   1.4e-06    0.0042      65     169 ..     216     329 ..     209     335 .. 0.67
   3 ?    2.9   0.0     0.029        86     148     168 ..     449     469 ..     430     472 .. 0.88

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0024
                 ESSS.EEEEEE-TTSS-EEEEESSSSCEEEEEECS..CEEEEEEE..EES--EEEE-TTSSEEEEE-TTSSS-EEEEEETT......TTEEEEEEE-.T CS
       eIF2A  57 kkegpihdvaWspkskefaviyGkmpakvslfdlk..vkviskle..eqkrNtiffspkgklvllaGfgnlaGeleiwdvk......kkkkiakaea.a 144
                 k +  i+dv+Ws  + + ++    ++ ++  +dl+  +  +s+l+  +++   + f+p+    ll+G ++   ++ +wd        ++++i+++ + +
  EEA21779.1 163 KDQLAIKDVKWSHGEFDTVIATAAANGRIITYDLQraGLELSRLSghSRQVHKLAFNPHRPAWLLSGSQDS--TIRMWDLRsaspaaTIQSISRYSSnS 259
                 56678********99999999999999*******87766666665115666789************99988..99****98444222333444333212 PP

                 T--.EEEE-T.TSSEEEEEE CS
       eIF2A 145 nat.lvewsp.dgryvlTat 162
                 +a+ ++ ws+ dg+ ++Tat
  EEA21779.1 260 DAVrDIRWSTgDGTVFATAT 279
                 22226788864788888887 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 1.4e-06
                 EEE-TTSS-EEEEESSSSCEEEEEECS....CEEEEEEEEES--.....EEEE-TTSSEEEEE-TTSSS-EEEEEETT..TTEEEE.EEE-TT--EEEE CS
       eIF2A  65 vaWspkskefaviyGkmpakvslfdlk....vkviskleeqkrN.....tiffspkgklvllaGfgnlaGeleiwdvk..kkkkia.kaeaanatlvew 151
                 +a +p++    ++ G +++++ ++dl+    +  i ++++ + N      i +s  +  v +a   +  G+++ wd    k  +++ +a+++ +  v+w
  EEA21779.1 216 LAFNPHRPA-WLLSGSQDSTIRMWDLRsaspAATIQSISRYSSNsdavrDIRWSTGDGTV-FATATDS-GAIQCWDYRqtKAPQLKiTAHEKPCYAVDW 311
                 555555444.4578999999****998777844444444444442222269998765554.4555554.*******99443334542556677999*** PP

                 -TTSSEEEEEE-TTT-SS CS
       eIF2A 152 spdgryvlTattaprlrv 169
                 +pdg++++ a t  +++v
  EEA21779.1 312 HPDGKHLVSAGTDRQVKV 329
                 **********99877766 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.029
                 EEEE-TTSSEEEEEE-TTT-S CS
       eIF2A 148 lvewspdgryvlTattaprlr 168
                  v wsp+g+ v+T    pr r
  EEA21779.1 449 AVAWSPTGEVVATVQKRPRRR 469
                 589************999987 PP

>> Zn_ribbon_17  Zinc-ribbon, C4HC2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   9.0     3e-05     0.089      16      53 ..    1189    1229 ..    1185    1232 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 3e-05
  Zn_ribbon_17   16 grvvlcgvCeHvlHasCarewfendd..laeCps.GCGckc 53  
                    g+   c+ C+H  H +C+++w+   +   + Cp+ GC  +c
    EEA21779.1 1189 GLWSWCQGCGHGGHLACMKKWLGDLEasEGGCPTpGCMHDC 1229
                    56678****************8766645689******7666 PP

>> HSP20  Hsp20/alpha crystallin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.2     6e-05      0.18      35      92 ..     637     692 ..     624     699 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 6e-05
                 EEE--..---TT----SS---EEEEEE--STTB-TTT-EEEEETTEEEEEEEBSS--. CS
       HSP20  35 kgeheeeeedekglikerssrkFsrkftLPenvdadkvkaslkdGvLtvtvpkkepek 92 
                 +++++  +e+ +  +k +    Fs + ++P++ +  kvk++l +Gv + ++ ++ +++
  EEA21779.1 637 ESNRR-PKEKANQGHK-SPHARFSDRTRVPDGSKSVKVKSHLFKGVIETDAHRRRTPE 692
                 23333.4444444444.58999**************************9999988775 PP

>> zf-rbx1  RING-H2 zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   2.4       1.1   3.2e+03       3      28 ..    1102    1132 ..    1096    1134 .. 0.62
   2 ?   12.7   0.7     4e-05      0.12      31      53 ..    1196    1222 ..    1182    1224 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 1.1
     zf-rbx1    3 CaiCrnele......eacieckapgdeecpvv 28  
                  C  C++++e      + c +c++p++  cp+ 
  EEA21779.1 1102 CYTCKKPYEnpvkdnRRCHRCRTPQSP-CPIC 1132
                  556666655333333457777777777.7765 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 4e-05
     zf-rbx1   31 eCgHaFHlhCiskWlkt....rkvCPl 53  
                   CgH  Hl C++kWl      +  CP+
  EEA21779.1 1196 GCGHGGHLACMKKWLGDleasEGGCPT 1222
                  6**************987776777885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1347 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       696  (0.0388198); expected 358.6 (0.02)
Passed bias filter:                      450  (0.025099); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.87u 0.29s 00:00:01.15 Elapsed: 00:00:00.46
# Mc/sec: 8836.18
//
Query:       EEA21780.1  [L=932]
Description: vacuolar ABC heavy metal transporter (Hmt1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.7e-35  123.0   6.9    1.7e-35  123.0   6.9    2.2  3  ABC_membrane  ABC transporter transmembrane region
    1.6e-33  116.1   0.0    5.9e-33  114.3   0.0    2.0  2  ABC_tran      ABC transporter
    1.3e-07   31.3   1.2    3.2e-06   26.7   0.3    2.6  2  SMC_N         RecF/RecN/SMC N terminal domain
     0.0037   17.5   0.1      0.031   14.6   0.1    2.4  1  AAA_22        AAA domain
  ------ inclusion threshold ------
      0.024   14.4   1.4        0.1   12.4   0.1    2.3  2  AAA_29        P-loop containing region of AAA domain
      0.031   14.5   3.3       0.19   12.0   0.9    3.0  2  SbcCD_C       Putative exonuclease SbcCD, C subunit
      0.061   13.2   0.0       0.13   12.1   0.0    1.5  1  RsgA_GTPase   RsgA GTPase
       0.15   12.4   3.3       0.36   11.2   0.6    2.6  2  AAA_16        AAA ATPase domain
        1.8    9.2   9.3        7.4    7.2   0.5    3.6  3  VanZ          VanZ like family


Domain annotation for each model (and alignments):
>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.3       1.6   3.2e+03     150     167 ..      35      52 ..      28      60 .. 0.47
   2 ?   -2.2   0.0       1.3   2.6e+03     150     173 ..     219     242 ..     202     251 .. 0.67
   3 !  123.0   6.9   8.6e-39   1.7e-35       2     274 .]     326     601 ..     325     601 .. 0.96

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 1.6
                   HHHHHHHHHHHHHHHHHH CS
  ABC_membrane 150 ilpliilvsaviakilkk 167
                   i++l+++v+a+i + +++
    EEA21780.1  35 IALLLAFVIAFIVSSISS 52 
                   333333333333333333 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.3
                   HHHHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane 150 ilpliilvsaviakilkklkkkeq 173
                   +l l++lv+ +i++++++ + ++ 
    EEA21780.1 219 VLTLLALVFLYIMSTSQSSNSRKA 242
                   445556666666666665555554 PP

  == domain 3  score: 123.0 bits;  conditional E-value: 8.6e-39
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSS...TCCHH...HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHH CS
  ABC_membrane   2 iliillailagvlsplfplvlgrildtlldk...gdpet...ealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsff 92 
                   ++++ l++l+ v+++l+p+  g i+d+l d+   g       + ++ +++++  l   q++++ l+s+l++ ++++  ++l + +f++++++++ f+
    EEA21780.1 326 VICFGLILLQRVINVLVPYQVGVITDILADDegkG---LpvpWFQICLYIFYRWLQGNQGLIGSLRSSLWIPVSQYSYMELSTAAFEHVHSLSLDFH 419
                   78999************************974433...2566999**************************************************** PP

                   HHSCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH.HSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane  93 dtnsvGellsrltndvsklrdglgeklglffqslltfvgglivmfy.lgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEsls 188
                     +++Ge+ls l++  s ++++l +  ++++  l+ + +++++ ++ + ++ +lv+ ++++++++v++ +a++  ++++++ +a  +  +v ++s+ 
    EEA21780.1 420 LGKKTGEVLSALSKGNS-INTFLEQVTFQVVPMLIDLGVAIGYFLIfFDPYYALVVAIVTFCYLYVTIRMAQWRAEIRRQMVNASRQEDAVKNDSMV 515
                   ************86655.**********************9999988************************************************** PP

                   THHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSTHHHHHHHHHHHHHHHHHH CS
  ABC_membrane 189 girtVkafgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttlvisgelsvgdlvvflslfailfgal 274
                    ++tVk+f++e+y+ +++  a++++++a + ++++  l+++ ++ +++l  ++++++++++v++ge +vg++v +l ++a+l+g+l
    EEA21780.1 516 SYETVKYFNAESYEFDRYRGAVRDFQNAEYHVLFSLTLMNTSQNTVFMLGLLVTCFIAAYQVSTGERQVGKFVSLLIYMAQLQGPL 601
                   ************************************************************************************96 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       5.4   1.1e+04     106     115 ..     574     583 ..     487     596 .. 0.46
   2 !  114.3   0.0   2.9e-36   5.9e-33       1     137 []     663     812 ..     663     812 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 5.4
                 SGGS-HHHHH CS
                 xxxxxxxxxx RF
    ABC_tran 106 pssLSgGqkq 115
                 ++++S G++q
  EEA21780.1 574 AYQVSTGERQ 583
                 2566666666 PP

  == domain 2  score: 114.3 bits;  conditional E-value: 2.9e-36
                 EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH......HHHTCHHHHHHHST CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxx RF
    ABC_tran   1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren......esdeeiekalsklg 93 
                 l+ +++++++g+++a+vGe+G GKSt+++ll + ++  +G+i++dg+d+++ ++ slr++igv+pq++ lf+e+ +++       + de++++a +  +
  EEA21780.1 663 LNGLTFECRPGTTTALVGESGGGKSTVFRLLFRFYDASSGSIRVDGQDVQDVTIDSLRRHIGVVPQDTVLFNETLMYNLkyacpdATDEQVYEACRAAS 761
                 6899**********************************************************************666659****988888777777777 PP

                 TGG.......TTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                 xxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  94 lke.......lkdtvvksspssLSgGqkqrvalarallkkpkllllDEpta 137
                 +++         +t+v++++  LSgG+kqrva+ar++lk+p+++llDE+ta
  EEA21780.1 762 IHDkilsfpdGYQTKVGERGLRLSGGEKQRVAIARTILKNPRIILLDEATA 812
                 77777777768899999999*****************************96 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0       0.6   1.2e+03      86     152 ..     502     569 ..     484     588 .. 0.71
   2 !   26.7   0.3   1.6e-09   3.2e-06     102     209 ..     695     852 ..     662     861 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.6
                 TTEE.SSSSSSCEEEEEEEETTSEEEEEETTEEE-HHHHHHHHHCTT-STTCS-HHHHHHHHHHHHHH CS
                 xxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  86 edkk.lkiekeevsisrrvkrkgeseykingkevtkkevsellesagiskelLSgGektLvalaLlfA 152
                  +++   +++++++   +vk  +  +y++++ +   ++ ++   ++ +s +l+   + t+ +l Ll+ 
  EEA21780.1 502 ASRQeDAVKNDSMVSYETVKYFNAESYEFDRYRGAVRDFQNAEYHVLFSLTLMNTSQNTVFMLGLLVT 569
                 33331344555555555555566668999999999999999999999999999999999999988875 PP

  == domain 2  score: 26.7 bits;  conditional E-value: 1.6e-09
                 EEETTSEEEEEETTEEE-HHHHHHHHHCTT-STT......................................................CS-HHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......................................................xxxxxxxxxxx RF
       SMC_N 102 rvkrkgeseykingkevtkkevsellesagiske......................................................lLSgGektLva 146
                 r +   + +++++g++v+   + +l ++ g+ ++                                                       LSgGek+ va
  EEA21780.1 695 RFYDASSGSIRVDGQDVQDVTIDSLRRHIGVVPQdtvlfnetlmynlkyacpdatdeqvyeacraasihdkilsfpdgyqtkvgerglRLSGGEKQRVA 793
                 55556666778888888888888888888888888888888888888888888888888888888888888999999999999999999*******999 PP

                 HHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC-SCEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 147 laLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQfivislreemlekadklv 209
                 +a        k   + llDe  aaLD +  +++ + l + sk   ++vi++r  ++++ad+++
  EEA21780.1 794 IART----ILKNPRIILLDEATAALDTETEEQIQDALATLSKGRTMLVIAHRLSTITDADQIL 852
                 8865....45666699*******************************************9986 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.1   1.6e-05     0.031       7      38 ..     675     723 ..     670     845 .. 0.60

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 1.6e-05
      AAA_22   7 ilvvtGesGtGKTtllrrlleqldeeakaee.................e 38 
                  ++++GesG GK+t+ r l++ +d+ +   +                  
  EEA21780.1 675 TTALVGESGGGKSTVFRLLFRFYDASSGSIRvdgqdvqdvtidslrrhI 723
                 6799*******************87544444555555555555444440 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   5.1e-05       0.1      14      39 ..     665     690 ..     662     692 .. 0.84
   2 ?   -0.2   0.1      0.44   8.7e+02      36      50 ..     843     857 ..     843     860 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 5.1e-05
      AAA_29  14 ghtieidlkgatlltGpsGsGKSTll 39 
                 g t+e ++  +t l+G+sG GKST++
  EEA21780.1 665 GLTFECRPGTTTALVGESGGGKSTVF 690
                 56778887779*************85 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.44
      AAA_29  36 STllDAiqalLvpak 50 
                 ST+ DA q+lL+ + 
  EEA21780.1 843 STITDADQILLLNDG 857
                 9**********9876 PP

>> SbcCD_C  Putative exonuclease SbcCD, C subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.1       3.5     7e+03      32      51 ..     576     595 ..     574     599 .. 0.76
   2 ?   12.0   0.9   9.7e-05      0.19      20      88 ..     771     826 ..     761     828 .. 0.74

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 3.5
     SbcCD_C  32 tlSGGekqflaylalaaala 51 
                 + S+Ge+q+   + l+  +a
  EEA21780.1 576 QVSTGERQVGKFVSLLIYMA 595
                 579****9988888876555 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 9.7e-05
     SbcCD_C  20 dgkekelsrssgtlSGGekqflaylalaaalaalyssaegrepalrlvfLDEAFsklDeesiatllell 88 
                 dg ++++ ++  +lSGGekq +       a+a  +       +++r+++LDEA + lD e+ +++ ++l
  EEA21780.1 771 DGYQTKVGERGLRLSGGEKQRV-------AIARTIL------KNPRIILLDEATAALDTETEEQIQDAL 826
                 6677777777778888888432.......2333333......359***************999887776 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   6.7e-05      0.13      87     130 ..     660     704 ..     639     716 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 6.7e-05
                  HTTHHHHHHHCTT.SEEEEECSTTSSHHHHHHHHCTT-----S-- CS
  RsgA_GTPase  87 kegleelkellkd.ktsvlvGqSGvGKStLinallpelelktgev 130
                  k +l+ l+ +++   t++lvG+SG GKSt+   l    +++ g++
   EEA21780.1 660 KPALNGLTFECRPgTTTALVGESGGGKSTVFRLLFRFYDASSGSI 704
                  5567778888887799**************999877666666655 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.6   0.00018      0.36      25      63 ..     674     713 ..     667     839 .. 0.52
   2 ?    0.1   0.3      0.46   9.1e+02      52     102 ..     856     907 ..     816     927 .. 0.52

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00018
      AAA_16  25 elvllsGesGvGKsslvrellralekd....ggiflrgkcdql 63 
                   + l+GesG GKs++ r l+r + ++    +   + g+ +q 
  EEA21780.1 674 TTTALVGESGGGKSTVFRLLFRFYDASsgsiR---VDGQDVQD 713
                 57889****************98888843330...44443333 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.46
      AAA_16  52 ggif.lrgkcdql.esaipysa.laqalareellrqlldeaesaeleawrekle 102
                 +g +  rg+ d+l e++ +y+  + +++ r +  ++l  ++++ + +  + + e
  EEA21780.1 856 DGQVtERGTHDELrEMNGRYASmWRKQI-RAQRAAELRGATAT-DDSSSQSEEE 907
                 3333366777777667777744377777.54555555555333.3333333333 PP

>> VanZ  VanZ like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.1   0.1         9   1.8e+04       3      17 ..      37      51 ..      34      62 .. 0.56
   2 ?    7.2   0.5    0.0037       7.4      67     111 ..     308     355 ..     218     358 .. 0.82
   3 ?    5.4   0.7     0.014        28       4     101 ..     470     582 ..     469     594 .. 0.58

  Alignments for each domain:
  == domain 1  score: -4.1 bits;  conditional E-value: 9
        VanZ  3 lylllllyliffpss 17
                l+l++++++i+ + s
  EEA21780.1 37 LLLAFVIAFIVSSIS 51
                445555555555444 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0037
        VanZ  67 fllplllkkk...flkvlllgfllslsiElhQlfvpgRsfdvdDviln 111
                 +++p+l+  k   +++v++++f+l l+  ++ ++vp++++ ++D++ +
  EEA21780.1 308 LFFPYLWPSKsrrLQFVVVICFGLILLQRVINVLVPYQVGVITDILAD 355
                 5677777666556667*****************************987 PP

  == domain 3  score: 5.4 bits;  conditional E-value: 0.014
        VanZ   4 ylllllyliffpssqnaeessslsglvskl............inlipfkeikrllkere......lea.li..vgnvalfvplGfllplllkkkflkvl 81 
                 y+l++++++f+    + ++ +   +++ ++             +++  +++k ++   +       +  ++  + n    v + + l+++ ++    v+
  EEA21780.1 470 YALVVAIVTFCYLYVTIRMAQWRAEIRRQMvnasrqedavknDSMVSYETVKYFN---AesyefdRYRgAVrdFQNAEYHVLFSLTLMNTSQN---TVF 562
                 5556666666666666655555544444443323333444431222222222222...12333443333346899999999999999999944...489 PP

        VanZ  82 llgfllslsiElhQlfvpgR 101
                 +lg+l+ ++i   Q+ +  R
  EEA21780.1 563 MLGLLVTCFIAAYQVSTGER 582
                 99**********99999844 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (932 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       884  (0.0493056); expected 358.6 (0.02)
Passed bias filter:                      573  (0.0319594); expected 358.6 (0.02)
Passed Vit filter:                        74  (0.00412739); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.79u 0.33s 00:00:01.12 Elapsed: 00:00:00.47
# Mc/sec: 6001.12
//
Query:       EEA21781.1  [L=360]
Description: esterase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.1e-52  177.5   0.0    4.6e-52  177.0   0.0    1.2  1  Abhydrolase_3  alpha/beta hydrolase fold
    6.7e-08   31.9   0.1    1.5e-07   30.7   0.1    1.6  1  COesterase     Carboxylesterase family
     0.0003   20.3   0.0       0.34   10.4   0.0    2.4  2  Peptidase_S9   Prolyl oligopeptidase family
  ------ inclusion threshold ------
      0.019   14.5   0.2      0.031   13.8   0.2    1.2  1  DLH            Dienelactone hydrolase family


Domain annotation for each model (and alignments):
>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  177.0   0.0     1e-55   4.6e-52       2     210 ..      95     322 ..      94     323 .. 0.88

  Alignments for each domain:
  == domain 1  score: 177.0 bits;  conditional E-value: 1e-55
                    EEE--STTTS--TTTTHHHHHHHHHHHTSEEEEEE---TTTS-TTHHHHHHHHHHHHHHHTHHHHTETTCEEEEEEETHHHHHHHHHHHHHHHTT. CS
  Abhydrolase_3   2 vyfHGGGfvlgsldthdalcrelakelgavvvsvdYrlAPehpfPaavedalaalrwlaeqawelgadpsrivlaGdSaGGnlaaavalrardeg. 96 
                    + fHGGG+vlg+l+++ a+cr++++e+g+vv+ vdYrlAPe pfP a+ d++aal+w  ++a++l++dp++i ++G S GG  +a++a+ ard++ 
     EEA21781.1  95 LNFHGGGWVLGGLKSEAAWCRSICNESGIVVIDVDYRLAPEFPFPVAIYDCWAALQWTIANAATLNIDPTSISIGGLSSGGLNTAVLAHFARDASp 190
                    68********************************************************************************************76 PP

                    ---EEEEEEESE-SST............SSTTSHHHHHCHHTTTSSSSCHHHHHHHHHHHS.S.....GGGGGSTTTSGGGCS-SST---EEEEEE CS
  Abhydrolase_3  97 epkvagqvliyPvtdl............ertesesikkaeeladgplltraaldlfwrlyl.p.....eadrddplaspllaedlsglpptlvvva 174
                    ++ ++ q+++ P+td+             ++e+  + +a   +d p+ + ++  +f+++y+ +      + +dd+++ p+l++ l++l+p+ +v+a
     EEA21781.1 191 RIDLKLQLMVVPATDMryipispdepvrLTPETCPYPSAIFCSDLPWSPLERESWFLKYYIgDdpqtrSKILDDWRMTPVLSPCLRDLAPAHIVTA 286
                    777*********888777776555554434444555444444777777799999*******62434444456899******988************ PP

                    TT-TTHHHHHHHHHHHHHTT--EEEEEETTEETTGG CS
  Abhydrolase_3 175 efDplrdegeayaerlraagvevelieyegmvHgfa 210
                    e+D+ rde+e+y + l+aag++v++++y+g++H+fa
     EEA21781.1 287 EYDIERDEAEHYGKMLQAAGNQVTMKRYPGVPHAFA 322
                    ***********************************8 PP

>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.7   0.1   3.4e-11   1.5e-07     102     201 ..      88     180 ..      44     191 .. 0.87

  Alignments for each domain:
  == domain 1  score: 30.7 bits;  conditional E-value: 3.4e-11
                 TSSEEEEEEE--STTTS-BGCG..S-THHHHHHHTSEEEEE----HHHHH-B-SSTTSBS-HHHHHHHHHHHHHHHHGGGGTEEEEEEEEEEETHHHHH CS
  COesterase 102 kkklPVlVwihGggfqtgsase..ydgsaLaaegnvivVtinYRlGvlGFlstgdeeapGNvGllDqvlALrWVkenIasFGGdpervtlfGesAGaas 198
                    +PV   +hGgg + g  ++  + ++++++e +++v+ + YRl +         e+p  v+++D  +AL+W   n a+ + dp ++ + G s+G+  
  EEA21781.1  88 PGPFPVHLNFHGGGWVLGGLKSeaAWCRSICNESGIVVIDVDYRLAP---------EFPFPVAIYDCWAALQWTIANAATLNIDPTSISIGGLSSGGLN 177
                 4678*************9876557999******************86.........889999**********************************976 PP

                 HHH CS
  COesterase 199 vsl 201
                  ++
  EEA21781.1 178 TAV 180
                 554 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.4   0.0   7.5e-05      0.34      45      85 ..     142     185 ..     140     227 .. 0.85
   2 !    7.4   0.1   0.00061       2.7     160     207 ..     293     340 ..     282     344 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 7.5e-05
                   HHHHHHHHHHHHHTT...S--GGGEEEEEETHHHHHHHHHHHH- CS
  Peptidase_S9  45 fdDfiaaaealakeg...yvdserlaitGgSyGGyltgaalnqr 85 
                   + D+ aa+++ +++     +d++ + i G S GG++t++++  +
    EEA21781.1 142 IYDCWAALQWTIANAatlNIDPTSISIGGLSSGGLNTAVLAHFA 185
                   67999999999776654679*****************9998755 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.00061
                   HHHHHHHHHHH--S-SEEEEEETTS-SSTTSSHHHHHHHHHHHHHHHH CS
  Peptidase_S9 160 aealklvaaLqkkgknvlllifpdegHgvgkprakveelarllaFlke 207
                    ea+++ + Lq +g++v ++ +p+  H ++  ++  + l++  +F+ +
    EEA21781.1 293 DEAEHYGKMLQAAGNQVTMKRYPGVPHAFAHYNHPTRGLRKSHEFIRD 340
                   68889999**********************999998999999999876 PP

>> DLH  Dienelactone hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.2     7e-06     0.031     149     195 ..     283     327 ..     277     350 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 7e-06
         DLH 149 alfgeeDefipadevekleealkaanvdlelkvYpgagHaFandsre 195
                 ++ +e D  i+ de+e+  + l+aa+ ++ +k Ypg+ HaFa  +++
  EEA21781.1 283 IVTAEYD--IERDEAEHYGKMLQAAGNQVTMKRYPGVPHAFAHYNHP 327
                 4455555..78888999************************987765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (360 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       253  (0.0141112); expected 358.6 (0.02)
Passed bias filter:                      245  (0.013665); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.49
# Mc/sec: 2226.06
//
Query:       EEA21782.1  [L=350]
Description: D-amino acid oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.1e-25   89.5   1.2    1.4e-24   87.3   1.2    2.1  1  DAO          FAD dependent oxidoreductase
    0.00012   22.5   0.8    0.00034   21.1   0.8    1.8  1  Pyr_redox    Pyridine nucleotide-disulphide oxidoreductase
     0.0014   17.9   0.4     0.0062   15.8   0.1    2.0  2  Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
      0.079   12.2   0.1       0.21   10.8   0.1    1.7  1  Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase


Domain annotation for each model (and alignments):
>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.3   1.2   3.2e-28   1.4e-24       2     347 ..       6     331 ..       5     336 .. 0.74

  Alignments for each domain:
  == domain 1  score: 87.3 bits;  conditional E-value: 3.2e-28
                 EEEECTSHHHHHHHHHHHHTT....EEEEESSSSTTSSGGGSSEEEEESSS....STHHSTHHHHHHHHHHHHHHHHHHHHHSSTTS.EEEEEEEEEES CS
         DAO   2 vviiGGGiiGlstAyeLarrg....VtllekgdiagsgaSgrnsgllhsgl....rylpeaselarlslealeelreleeelgidid.yrrtGllslaa 91 
                 +vi G+G+iGl +A eL++rg    Vt++  +  +g  +S   +  ++++     +   +a   +r+ ++++ ++ e+ ++   +   +++t +  + +
  EEA21782.1   6 IVILGAGVIGLDVAIELSKRGygkyVTVIAEH-LPG-DSSIDYTSPWAGANfsgiS-GGDA-NALRWDRAGYTLMMEMIDKKSTEAKfLEKTESTEY-W 99 
                 9*******************888*********.***.8888888888776656544.3333.344******99995555554555553444555555.3 PP

                 SHHHHHHHHHHHHHHHHTTTTEEEEEHHHHHHHSTTSTTTSEEEEETTEEEEEHHHHHHHHHHHHHHT..T.-EEEESECEEEEEEEETCEEEEEEECT CS
         DAO  92 deeelealdkllallleagldaelldaeevrelepalpgllgalfypdtgqvdpakltaalaraaeal..G.veilegtevtgleeedgkvwgverttp 187
                 d  e+++  +++++ +e+  d  ++ ++      p  +g++ ++ +++  ++++ + ++ l++ + +   G v +++  +v +l++     + +     
  EEA21782.1 100 D--EMPQP-DKIQSMTEYLRDLVIIPQK----ELP--AGVAFGIKFTT-VTINAPAHCQHLQNLLSQPeyGsVPFIRW-RVSRLQD-----AFL----- 177
                 4..36665.4455554333343345553....334..48888899999.99*********999987763333666665.6666622.....334..... PP

                 EEEEEEEEEEE--GGGHH.HHHTTCTTTSEEEEEEEEEEEEEECCTHSTGSGCSEEEEEEEETTTTEEEEEE..TTSEEEEEESSEEETTCSSTSCSHH CS
         DAO 188 gendaadavVnaaGawsd.llgllkeldlpispvrgqvlvlkplseklvspaailpvpetdddgrgvyvtpr..kdgrvlvGgtadeesgdddpevdee 283
                   n   + v n+ G  +  l+   +  d + +p+rgq+lv+k +s k++          ++ dg+ +yv+pr   dg+v++Gg    ++g  +p v ee
  EEA21782.1 178 SKN--TKLVFNCIGNSAItLS---GVSDSKCYPTRGQILVVKAPSVKQNIM--------RHGDGYETYVIPRplSDGTVILGGYM--QKGNSYPNVKEE 261
                 333..478******8876554...5558899**********6655544333........9999********98879*******98..999999****** PP

                 HHHHHHHHHHHHSGGG....CGEEEEEEEEEEETTSSEEEEEEE..TEEEEEEEEECTTTHHHHHHHHHH CS
         DAO 284 didellealrklfPql....gdvlrkwaGlrplpdglpligetp..gvkglylatGhsghGltlapatGk 347
                 + + +l++  +l+P l     +++r+ +Glrp + g+  + +++    k +++++G++g G++ +++++ 
  EEA21782.1 262 ESQSILKRTGELLPVLlngeVEIVRTVVGLRPSREGGARVEQETlsSEKIVIHNYGAGGTGFQAGIGMAV 331
                 ***************6574456889*******876666666633466779*****************986 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.1   0.8   7.6e-08   0.00034       1      29 [.       5      35 ..       5      38 .. 0.86

  Alignments for each domain:
  == domain 1  score: 21.1 bits;  conditional E-value: 7.6e-08
                EEEEECSSHHHHHHHHHHHH..TTSEEEEEE CS
   Pyr_redox  1 kvvvvGgGyiglElAgalae..lgkkVtvve 29
                ++v++G+G+igl++A +l++  +gk Vtv+ 
  EEA21782.1  5 SIVILGAGVIGLDVAIELSKrgYGKYVTVIA 35
                69****************6633779****96 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.1   1.4e-06    0.0062     143     172 ..       4      35 ..       1      39 [. 0.82
   2 ?   -0.6   0.0      0.14   6.1e+02     227     263 ..     281     316 ..     253     324 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 1.4e-06
                  SEEEEES-SHHHHHHHHHHHHHT-..EEEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxx..xxxxxx RF
  Pyr_redox_2 143 krivvvGgGyiGvElAaalaklgk..evtlve 172
                  ++iv+ G+G+iG+++A++l+k g+   vt++ 
   EEA21782.1   4 DSIVILGAGVIGLDVAIELSKRGYgkYVTVIA 35 
                  689****************8886642588875 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.14
                  EESEEEE-S-EEES-HHCSHCCT-EEEETTEEE--TT CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 227 dadlvvvavGvrpstelleeklglelderggivvdef 263
                  +++ v + vG+rps+e+   ++  e+ +  +iv+  +
   EEA21782.1 281 EVEIVRTVVGLRPSREGG-ARVEQETLSSEKIVIHNY 316
                  577889999*****9996.777777777777777665 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.1   4.6e-05      0.21       1      35 [.       7      42 ..       7      50 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 4.6e-05
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledyl.ilEkgnigns 35
                 +I GaG +Gl +aiel k g  +y+ ++  +  g+s
   EEA21782.1  7 VILGAGVIGLDVAIELSKRGYGKYVtVIAEHLPGDS 42
                 79******************9766526665555655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (350 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       352  (0.019633); expected 358.6 (0.02)
Passed bias filter:                      339  (0.0189079); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.31s 00:00:00.85 Elapsed: 00:00:00.49
# Mc/sec: 2167.87
//
Query:       EEA21783.1  [L=541]
Description: amino acid permease [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   5.3e-115  384.8  43.0     6e-115  384.6  43.0    1.0  1  AA_permease    Amino acid permease
    4.7e-23   81.7  49.8      9e-23   80.8  49.6    1.5  1  AA_permease_2  Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  384.6  43.0  6.7e-119    6e-115       1     475 [.      48     499 ..      48     503 .. 0.98

  Alignments for each domain:
  == domain 1  score: 384.6 bits;  conditional E-value: 6.7e-119
  AA_permease   1 hvlvialggviGtglfvglgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgpelGfviGlnylfswitvlaleltaas 98 
                  h+++ialggv+G+ ++ g+g +ls  Gp+gal++++++g+ +f+vm+slge+at++p  g+f+ +a rf++p+++++ G+ny+++w+++l+ e++ +s
   EEA21783.1  48 HIQMIALGGVVGASIWYGTGTALSYSGPVGALISFAVIGLDVFFVMQSLGELATLYPTPGAFTELAGRFIDPAVSVALGWNYWYMWVANLMSEYNLIS 145
                  9************************************************************************************************* PP

  AA_permease  99 iliqfwelvtdlpkawvtgavflvvlliinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkgagfrflgdngsifknnlppgfakeeeg 196
                  i++++w  ++++p  ++++++f++++  i ++gv vyge+ef+la+ kii+++  +++ i +++g+ + +  gfrf++++g      + +g       
   EEA21783.1 146 IVLTYW--TDKVP-SYGWILIFWAIYQSIAFFGVIVYGEVEFWLAIWKIICVLVGYLLAILVNTGAIGGDYIGFRFWSNPGP-----FANG------- 228
                  ******..*****.**************************************99999999999999999888**********.....****....... PP

  AA_permease 197 afknfisvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasa.aspfvifikesgvsvlaplin 293
                   + +f   fv +++ f+G+e++ai+agE+++P++++Pkai q+++ri+++++++++++g+lv+ +d++ll++  +a +sp  i+++++g++++++lin
   EEA21783.1 229 -INGFGQSFVLAAVYFSGTEMIAITAGESRNPKRDVPKAIQQTIYRIVLIFIGMVFFAGILVSSDDPNLLTAGSKAgKSPWSIALQNAGWKHAPDLIN 325
                  .*********************************************************************9888888********************* PP

  AA_permease 294 aviltaalssansslysasRvlyslakdglaPkvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliilsylrfR 391
                  ++ilta +s++ns++y+asRvl+sla  g aP++l+k + rgvP+ a lls +++l+al++ +  ++  ++f+++l i+++++++ w +i +++lrfR
   EEA21783.1 326 MFILTASFSAMNSAIYIASRVLHSLAGMGRAPAILGKTTSRGVPIYAALLSNLMGLIALINVATGAG--TAFTYILDIAGAAAFVAWACIGITHLRFR 421
                  ***********************************************************99999999..***************************** PP

  AA_permease 392 kalkyqgrsieelgfkaallplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfliilvgvklhvknkrp 475
                  +a+k+qg+  +el+f+a l+p+g+++v +++i++lli+++  +lt       w++++f+++y+iv+lf++++vg+kl +k+ + 
   EEA21783.1 422 RAWKLQGHTPDELPFRAFLFPYGAYFVTFLNIFLLLIQGYGSFLT------PWQPVTFVFSYIIVVLFVVLFVGWKLLKKTQFV 499
                  *********************************************......8**************************999876 PP

>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.8  49.6     1e-26     9e-23       8     421 ..      51     481 ..      44     489 .. 0.71

  Alignments for each domain:
  == domain 1  score: 80.8 bits;  conditional E-value: 1e-26
  AA_permease_2   8 alvigsvigsgifvkn..laasggpalilwvwiavligslavllvyaElssalprsgGiyvytkaafgkkvaflsawfnwfayvpvlasilsvaas 101
                    ++++g v+g+ i   +  ++ + gp+ +l+ + ++++ ++ v+  + El+++ p+ g     + +++ + v    +w +w+ +v+ +  + ++++s
     EEA21783.1  51 MIALGGVVGASIWYGTgtALSYSGPVGALISFAVIGLDVFFVMQSLGELATLYPTPGAFTELAGRFIDPAVSVALGWNYWYMWVA-NLMSEYNLIS 145
                    67888888877755544544458888655555555555578888999*************************************9.5578899*** PP

  AA_permease_2 102 yllnalgpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfssl....stetdt..ffpngwpgvl 191
                      l+ +  ++      ++li++ai+  +a+   +g+  ++ + ++l+i+ki+  +++  +l++++ + g            +++   f+ng +g+ 
     EEA21783.1 146 IVLTYWTDKVPSY--GWILIFWAIYQSIAF---FGVIVYGEVEFWLAIWKII-CVLVGYLLAILV-NTGAIG-GdyigFRFWSNpgPFANGINGFG 233
                    **99998776443..455555666666665...5888999999999999994.444433333333.222111.123354445554478889999** PP

  AA_permease_2 192 lgllivlwsfdGfesaanvsee..vkkkdvpkai..figllivlvlyllvniaflgvvpddei...anlsnlgsvaalffeavggkvvaiivvili 280
                     ++  ++ +f+G e++a  + e  ++k+dvpkai   i  ++ +++++++ +a + v++dd     a ++   s++++ ++++g k +  +++++i
     EEA21783.1 234 QSFVLAAVYFSGTEMIAITAGEsrNPKRDVPKAIqqTIYRIVLIFIGMVF-FAGILVSSDDPNlltAGSKAGKSPWSIALQNAGWKHAPDLINMFI 328
                    **********************666679******6533333333333333.333445555555476333333458********************* PP

  AA_permease_2 281 alsllgaintavigssrvlealardgvlPrffakvnkfgspiraiiltaivslillllfllassaaynfllsvsslgliisyllliigalilrkkr 376
                      +++ a+n+a++++srvl++la  g  P  + k+  +g pi+a  l+++  li l+ ++++ ++a++++l+++  ++++ ++ + i+ l  r+  
     EEA21783.1 329 LTASFSAMNSAIYIASRVLHSLAGMGRAPAILGKTTSRGVPIYAALLSNLMGLIALINVATGAGTAFTYILDIAGAAAFVAWACIGITHLRFRRAW 424
                    ****************************************************99888888777***************999998888777777664 PP

  AA_permease_2 377 phlkr.............pgkilvaiigalfllfllvalffppkgpatqssliytiil 421
                    + ++              +g++ v+++ +++ll+  +  f+ p +p+t + + y i++
     EEA21783.1 425 KLQGHtpdelpfraflfpYGAYFVTFLNIFLLLIQGYGSFLTPWQPVT-FVFSYIIVV 481
                    533223457765565543333444444444444444444443333333.333333222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (541 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       712  (0.0397122); expected 358.6 (0.02)
Passed bias filter:                      276  (0.0153941); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.45
# Mc/sec: 3610.58
//
Query:       EEA21784.1  [L=693]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.5e-22   79.9   4.0    2.5e-22   79.2   4.0    1.4  1  Fungal_trans  Fungal specific transcription factor domain
     0.0023   18.0  10.3     0.0041   17.2  10.3    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.2   4.0   2.8e-26   2.5e-22       1     265 [.     274     506 ..     274     518 .. 0.76

  Alignments for each domain:
  == domain 1  score: 79.2 bits;  conditional E-value: 2.8e-26
  Fungal_trans   1 ldrffsnfhpqfpilhk.psflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilq. 95 
                   +++ff  ++pqfp+l + ++ +p+t          ++++ll+ai+++ ++f+  ++  s   + s  +++  + +++++l   d  s+++ + ++q 
    EEA21784.1 274 IELFFRFINPQFPVLSEtNKPSPQT----------SPTHLLAAIYSITQPFTLFDDYLSIELAYSPPSPQTLTNIAWRSLN--DEISEPT-IRSVQt 357
                   689**************9999****..........****************999988773333333344444556999999..8888888.9****9 PP

  Fungal_trans  96 sLlllelyektss..dralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlp..LPcd 188
                   sL ll   +k+    + +l + ++g++v++a++lgL  +p  ++      l++ee+e+r+Rl w ++++Dk++a+ lGrp++++ ++  +    P +
    EEA21784.1 358 SLILLLQPCKNPLllESPLKWSLLGLTVSMAQTLGLYLDPTAWN------LPAEEIETRKRLSWLVWSVDKWLAFSLGRPNHISRNDWLITdlNPSN 448
                   78777777777665689999************************......*******************************6665555555216666 PP

  Fungal_trans 189 dddlwesddaseetlvetklsneeksrkiasfllaLkkilskiagsllsiekqlqqrdlqseklswveeleraldnW 265
                   d     +d+ +e++  +               + +L +il  ++ +l+s+++ + +   ++   s  + +   ld+W
    EEA21784.1 449 DA----TDHSNESYATH---------------FAKLTNILDTVLTELYSVRSVSILATDSQRTISTARPIMQTLDEW 506
                   66....55555555555...............567777777777777776666555555544444444444444444 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2  10.3   4.5e-07    0.0041       1      35 [.      29      64 ..      29      69 .. 0.84

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 4.5e-07
                SS-HHHHHCT---ST.SSSS-HHHHHCTHHHCCCCT CS
     Zn_clus  1 haCdnCrkkKvKCda.kkPaCsnCkklnleCtfyse 35
                +aCd Cr++K+ C     P C+ C+ ++  C+f ++
  EEA21784.1 29 RACDFCRSRKSACQIeVAPPCRMCRAHGQRCEFTDR 64
                69************985555************6665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (693 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       350  (0.0195214); expected 358.6 (0.02)
Passed bias filter:                      271  (0.0151152); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.27s 00:00:00.89 Elapsed: 00:00:00.46
# Mc/sec: 4500.43
//
Query:       EEA21785.1  [L=239]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-28   99.4   0.0    1.7e-28   98.9   0.0    1.3  1  DUF498    Protein of unknown function (DUF498/DUF598)


Domain annotation for each model (and alignments):
>> DUF498  Protein of unknown function (DUF498/DUF598)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.9   0.0   9.3e-33   1.7e-28       1     109 []     102     232 ..     102     232 .. 0.85

  Alignments for each domain:
  == domain 1  score: 98.9 bits;  conditional E-value: 9.3e-33
                 EEEEESSEEEE.TTEE...ESSEEEE-SSSEEE-T...............HCSTTCEE........CHHHHHHCT..T..SEEEEE-TTS-----HHHH CS
      DUF498   1 idaygeggfel.ngvk...ysgsllvlpeeafawd...............vakaedlt........eeslellellepkpellilGtGkrqlplspevr 72 
                 +da+ ++gf+l ng k   ++g llv  +eafaw+               v      +        ee+++ll l++p+p+ll+lG+G+++ plsp+++
  EEA21785.1 102 VDACLDDGFHLdNGIKvtnGDGVLLVA-GEAFAWRpwqllkntenpkrsmV------NekgqfelpEEAWGLLSLVWPRPDLLVLGLGSTIIPLSPQTK 193
                 799********9997755567777777.99****64578776666555551......044555555********************************* PP

                 HHHHCCTSEEEEE-HHHHHHHHHHHHHHT..--EEEEEE CS
      DUF498  73 ealnelgigvevmdtraAartyNllaaeg..rrVaaaLi 109
                 +++n+lg++ve++dtr+A +++Nlla+e+   +Vaaa+i
  EEA21785.1 194 RHINSLGMRVEIQDTRNASAQFNLLATERgvTEVAAAMI 232
                 *************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (239 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       264  (0.0147247); expected 358.6 (0.02)
Passed bias filter:                      242  (0.0134977); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.25s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 1716.45
//
Query:       EEA21786.1  [L=594]
Description: alkaline phosphatase Pho8 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.3e-106  357.0   0.0   1.6e-106  356.7   0.0    1.1  1  Alk_phosphatase  Alkaline phosphatase
    4.7e-06   26.2   0.1      1e-05   25.0   0.0    1.6  2  Metalloenzyme    Metalloenzyme superfamily


Domain annotation for each model (and alignments):
>> Alk_phosphatase  Alkaline phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  356.7   0.0  1.8e-110  1.6e-106       1     415 [.      96     543 ..      96     544 .. 0.88

  Alignments for each domain:
  == domain 1  score: 356.7 bits;  conditional E-value: 1.8e-110
                      -SEEEEEEETT-SHHHHHHHHHHHCHCTCSSSTTS.TTGGG-SEEEEEESSECSTTSSGHHHHHHHHHHSSBTBTT-BSB-TTST-B---HHHH CS
  Alk_phosphatase   1 aknvilligDGmgvstvtaaRslkeqakdklgeetllamdrfplvglsktyavdkqvtDSaataTAyacgvktyngaigvdaaagkevksvlea 94 
                      ++n+i++++DGmg+++++ +Rs+++ + + + ++tl  +dr  ++g+s+t+++ + vtDSaa+aTA++cg k+yngai+v ++ +  + +vlea
       EEA21786.1  96 KRNIIFMVSDGMGPTSLSLTRSFRQLELGLPANDTL-VLDRH-HIGTSRTRSSSSLVTDSAAGATAFSCGYKSYNGAISVLPN-HTACGTVLEA 186
                      69****************************977776.56664.7***************************************.********** PP

                      HHHTT-EEEEEEEEETTSHHHHTTTTTBSSTTSSSHHHSTCCCHHTTS-SHHHHHHHCST-SEEEEESCGGGSBCSBCTSSTCCT.SBHHHHHC CS
  Alk_phosphatase  95 AkkaGkstGlVtTtritdAtPaalvahvesRkwkedaavpaealeegkkdiaeqlikakkidvllGGGrkeffpaeyatdGerkdGrnlieeak 188
                      A+ aG++tGlV+TtritdAtPa + +h + R  +ed+         ++++i e+++ +  +d++lGGGr +f+pa+ ++ G r d r+l++ a+
       EEA21786.1 187 AHLAGYKTGLVVTTRITDATPACFASHANRR-EYEDLI--------AEQEIGEHPLGR-VVDLILGGGRCHFLPAN-VEGGCRADDRDLTKVAQ 269
                      ***************************9888.677777........79**********.*************8876.567999999******** PP

                      CTTCEEE-SHHHHHHHCTST..SSCEEEESSSSSCS-CCCS..CTCCE--HHHHHHHHHHHH....TTSTT-EEEEEEETCHHHHHHTTTHHHH CS
  Alk_phosphatase 189 kkgyqyvsdrkeLlkakeen..vkplLGLFadgdlkveldr..deatdPsLkemtevAiklL....sknekGFFLlVEGsrIDhaaHendavga 274
                        g++y+sdr+ +   +  +  + plLGL a+ d+++e+dr  +++t+PsL+emt++ + +L    +  e+GFF+++EGsrIDha+H nd++ +
       EEA21786.1 270 DMGFHYISDRSGFDGLNVGQdvKLPLLGLLAERDIPYEIDRrfQNETYPSLEEMTRTSLAALkkatESSEHGFFIMIEGSRIDHAGHGNDPAAQ 363
                      ***********9655444443479****************95558899**************655555679*********************** PP

                      HHHHHHHHHHHHHHHHHCHH.CTTEEEEEEESSEESEEEESTTST.......T..TTSEECCEET.TTSSEE...................... CS
  Alk_phosphatase 275 lsEvvefdeAvkaalefakk.eketlvvvTaDHshvfsfggyttr.......gesvlglepllaa.dkkpvl...................... 337
                      ++Ev++ d+A++a+l+f +k ++ t++v+T+DH++    gg+ +        +e+ + + +l++a +++++l                      
       EEA21786.1 364 VHEVLAYDKAFAAVLDFIEKeDTPTVLVATSDHET----GGLAVArqlhksyPEYKWLPDVLAKAsHSGEYLqkklniylsssskadtlgkrre 453
                      *******************98899***********....5555444566899********999887999999*******************888 PP

                      ..........CEEECCSTT....BTTB.....HHHHTSTT....EEE..SSHTEE-SSEEEEEESTT.GGGGSCEEECCHHHHHHHHHCT CS
  Alk_phosphatase 338 ..........lllYgngeetke.lkgvredvtakeskeadyrkraavpltseeHtgedvavfAygpk.aelvrGvqeqteiakvlaaale 415
                                l + + ++e++  l + + +v  +  +    ++ra+v++++++H+g+dv+++A + k a+ ++G++e+te++++la+ l 
       EEA21786.1 454 yvrksllkegLGIQDATDEEVDsLLNPDSEVPPSYVFADMISRRAQVGWSTHGHSGVDVNIYASSTKdAWPLHGNHENTEVGNFLASYLD 543
                      88888777665555555554444455555555566666669**********************98762699**************98875 PP

>> Metalloenzyme  Metalloenzyme superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.0   0.0   1.2e-09     1e-05     123     187 ..     331     398 ..     300     431 .. 0.79
   2 ?   -4.0   0.0      0.82   7.3e+03      44      64 ..     515     536 ..     513     537 .. 0.84

  Alignments for each domain:
  == domain 1  score: 25.0 bits;  conditional E-value: 1.2e-09
                    HHHHH.CC.-S.EEEEEE-HHHHHHHTT-HHHHHHHHHHHHHHHHHHHTTS-TTTE..EEEEE-SSB- CS
                    xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxx RF
  Metalloenzyme 123 aldailsgkfd.lvvvniknaDmvGHtgdleatiaaieaaDeavkeildaieqvdg..ilvvtADHgn 187
                    + +a +s+++  ++++     D +GH +d++a+++ + a+D+a + +ld ie++d+  +lv t+DH +
     EEA21786.1 331 LKKATESSEHGfFIMIEGSRIDHAGHGNDPAAQVHEVLAYDKAFAAVLDFIEKEDTptVLVATSDHET 398
                    333334444447999*************************************999633788899**87 PP

  == domain 2  score: -4.0 bits;  conditional E-value: 0.82
                    SEEEEEESSS.TT----HHHHH CS
                    xxxxxxxxxx.xxxxxxxxxxx RF
  Metalloenzyme  44 kahgtavglp.eddmgnsevgH 64 
                     a+ t+ ++p ++  +n+evg+
     EEA21786.1 515 YASSTKDAWPlHGNHENTEVGN 536
                    5788899999999999999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (594 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       484  (0.0269954); expected 358.6 (0.02)
Passed bias filter:                      437  (0.0243739); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.31s 00:00:00.92 Elapsed: 00:00:00.47
# Mc/sec: 3770.65
//
Query:       EEA21787.1  [L=301]
Description: hypothetical protein PMAA_055810 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-19   70.6   0.2    2.4e-19   69.5   0.2    1.6  1  DUF3425   Domain of unknown function (DUF3425)
  ------ inclusion threshold ------
       0.32   10.2   3.3       0.41    9.9   3.3    1.1  1  ORC6      Origin recognition complex subunit 6 (ORC6)


Domain annotation for each model (and alignments):
>> DUF3425  Domain of unknown function (DUF3425)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.5   0.2   2.7e-23   2.4e-19      16     122 ..     185     275 ..     172     277 .. 0.88

  Alignments for each domain:
  == domain 1  score: 69.5 bits;  conditional E-value: 2.7e-23
     DUF3425  16 eklpenlrPtelQlriaHpveidvlpwpelRdrllrafqeeeidedeffrdvvs......tlivWsieeeeletaeissaelsagdvtdlegWelkesF 108
                 + lp  l+Pt  Q +++H++++d++p+p++Rd l+ra +  +id+  +++d++       + + W                   ++++d++gWe++e F
  EEA21787.1 185 SDLPLALQPTTTQYKVPHHPWLDLIPIPKMRDHLIRAGD--SIDDVKLCYDMCGyrvpetGILIW-------------------KEPWDPSGWEVTERF 262
                 34**********************************544..5**********9888888888899...................47************* PP

     DUF3425 109 frkYpylvdglele 122
                 ++ + + v++ ++e
  EEA21787.1 263 LQLWGWAVRD-CWE 275
                 ********99.776 PP

>> ORC6  Origin recognition complex subunit 6 (ORC6)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   3.3   4.5e-05      0.41     116     178 ..      33      90 ..       2     112 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 4.5e-05
        ORC6 116 TPtKsktlktalsasksssplkrrrklaneedgeeeeedapswvstsirdsrpeisrtlspsk 178
                  P K+k+l++ l++ + +++++ +r+ ++++d + + ++     +++   ++p++++t++p +
  EEA21787.1  33 DPKKRKKLQNRLNQRAHRRRQRALRTQQQQKDADIDVKQ-----EPDTDSNQPPTNSTNPPRS 90 
                 59999*999998888888888888888888888888444.....4455567778888876654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (301 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1188  (0.0662614); expected 358.6 (0.02)
Passed bias filter:                      712  (0.0397122); expected 358.6 (0.02)
Passed Vit filter:                        74  (0.00412739); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 1931.30
//
Query:       EEA21788.1  [L=80]
Description: hypothetical protein PMAA_055820 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      0.001   18.3   0.0     0.0013   18.0   0.0    1.1  1  Aldo_ket_red  Aldo/keto reductase family


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   7.5e-08    0.0013     255     294 .]      11      50 ..       7      50 .. 0.94

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 7.5e-08
                   TT-SEEEE--SSHHHHHHHHGGGG----HHHHHHHHHHH. CS
  Aldo_ket_red 255 pavgivipgasnieqlednldalelklseeevaeldelle 294
                   +a++ivipg+++++++e+n ++ e+++ +ee++e++++++
    EEA21788.1  11 EAGMIVIPGTTKLKRVEENRASREIEFAQEEFQEMRRIID 50 
                   5789********************************9975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (80 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       811  (0.045234); expected 358.6 (0.02)
Passed bias filter:                      611  (0.0340789); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.28s 00:00:00.71 Elapsed: 00:00:00.45
# Mc/sec: 539.89
//
Query:       EEA21789.1  [L=556]
Description: hypothetical protein PMAA_055830 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (556 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       654  (0.0364772); expected 358.6 (0.02)
Passed bias filter:                      495  (0.0276089); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.61u 0.29s 00:00:00.89 Elapsed: 00:00:00.47
# Mc/sec: 3531.86
//
Query:       EEA21790.1  [L=425]
Description: cell wall glucanase (Utr2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.5e-43  147.1   1.6    6.2e-43  146.3   1.6    1.4  1  Glyco_hydro_16  Glycosyl hydrolases family 16
     0.0025   18.2  13.8     0.0025   18.2  13.8    1.7  2  Chitin_bind_1   Chitin recognition protein


Domain annotation for each model (and alignments):
>> Glyco_hydro_16  Glycosyl hydrolases family 16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  146.3   1.6   6.9e-47   6.2e-43       3     176 ..      94     267 ..      92     273 .. 0.92

  Alignments for each domain:
  == domain 1  score: 146.3 bits;  conditional E-value: 6.9e-47
                     TTB-SEE-GGGEEEETTSEEEEEEEEEEEEEEEE.CCEESSEEEEEEEE---STTEEEEEEEETGGTSTTEEEEEEEETT-TTEEEEEEEBTTBS CS
  Glyco_hydro_16   3 eefevtwsksavsvengetltltldkesgsriks.kksflyGkvearikaaksaGvvtafylssedekahdEiDiEflGndtgkvqtnvygkGkg 96 
                     +e+++++s++ + ++ng +l l + + s +++ s +++++yGkv+a +k++++aGvvtaf+l+s   +a+dEiD+Ef+G + +++qtn+y++G  
      EEA21790.1  94 TEYDWMYSGTPL-THNG-ELILAMGNGSVGTLVSyNHYIWYGKVSAMLKTSRGAGVVTAFILMS---DAKDEIDYEFIGANLTTAQTNFYFQGLL 183
                     689999999998.6678.9*******997788887****************************9...9*************************** PP

                     GE..EEEEETSS-TTTS-EEEEEEEETTEEEEEETTEEEEEEESSHHH.HT.....--EESEEEEEEEEEEBSHHHSSE-EEEEEEE CS
  Glyco_hydro_16  97 kr..ekrlslwfdptedfHtYaieWtpdkikfyVDgkpvrtltkkeae.ev....kyPqftpmkvavslwpgsdwateqgkvkidwa 176
                     ++    + +  ++  +++H Y+i+Wtpd +++y+Dgk vr+l+k+++  ++    +yPq tp+++++slwpg+  +++ g  +i wa
      EEA21790.1 184 DYhnGVNATIDSNSFDNYHLYEIDWTPDAVTWYLDGKSVRVLKKTDTYnATsknfEYPQ-TPSRLQLSLWPGGLASNAPG--TIAWA 267
                     *75677777899**********************************99555875567**.*************9999999..99997 PP

>> Chitin_bind_1  Chitin recognition protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2  13.8   2.8e-07    0.0025       7      35 ..      25      53 ..      20      55 .. 0.87
   2 ?   -3.3   0.3       1.5   1.4e+04      30      36 ..      63      71 ..      61      72 .. 0.62

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 2.8e-07
                   TT---STT-.EE-TTSBEEBSHHHHSTT-- CS
  Chitin_bind_1  7 ggatCplnv.CCSqyGyCGttsdyCgagCq 35
                   gg++Cp++v CCSqyG CGt+ +yC  gC 
     EEA21790.1 25 GGTKCPDSVpCCSQYGQCGTG-AYCLGGCD 53
                   89******9**********76.8**87895 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 1.5
                   HSTT..--B CS
  Chitin_bind_1 30 Cgag..Cqs 36
                   C+ +  Cqs
     EEA21790.1 63 CTPEpiCQS 71
                   644456888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (425 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       786  (0.0438396); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.23s 00:00:00.73 Elapsed: 00:00:00.39
# Mc/sec: 3284.93
//
Query:       EEA21791.1  [L=417]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (417 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       609  (0.0339673); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2854.19
//
Query:       EEA21792.1  [L=527]
Description: proline oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.5e-61  207.8   0.1    3.2e-61  207.5   0.1    1.1  1  Pro_dh    Proline dehydrogenase


Domain annotation for each model (and alignments):
>> Pro_dh  Proline dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  207.5   0.1   1.8e-65   3.2e-61       2     295 ..     158     508 ..     157     509 .. 0.78

  Alignments for each domain:
  == domain 1  score: 207.5 bits;  conditional E-value: 1.8e-65
                 HHHHHHHHHTTE.EEEEEES-S.................S--SHHHHHHHHHHHHHHHHHHHHHHCCS-T.......TCC-S..EEE-GGG....TT-S CS
                 xxxxxxxxxxxx.xxxxxxxxx.................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxx..xxxxxxx....xxxx RF
      Pro_dh   2 kktieklkkrgv.rlsldllge.................avlteedadryleayleaiksiekaskalkv.......leapg..vsvklsa....prle 69 
                 +kti++lk+ g+  ++l + +e                 +        ++ e+  +a +++++ ++ +k+       l+++g  v++k+++       +
  EEA21792.1 158 RKTIADLKQLGYaGVILGYGREvvmdgdetssferqgakE------GGSRGEEKINAEQTLREIRE-WKEgtmqtveLADEGdfVALKFTGagreALRH 249
                 6888888844885577766666444444444442222221......22222222222222222222.33355555555555577*******98533444 PP

                 GGGHHHHHHHHHHHHHHHHHHHHHTT-EEEE----GGGHH....HHHHHHHHHHHSCCTTT---..EEEEEETTBTTHHHHHHHHHHHHHHTTS-EEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      Pro_dh  70 taeeeevmeelverlrtlakeakelgvrlliDaEeaklqe....ltlelfrklnkepelkdwev..vgntyQaYlkdalevlqkllelAeregfrlgvk 162
                   +      +l e++ +++++ak++++ ll+DaE++++q     ++l+l+r++n+  ++++ +   ++ntyQaYl++++++l  +l+ +++e+f lgvk
  EEA21792.1 250 LVQGLPPSPALQEAIYEICDRAKDRKILLLFDAEQHAVQGtidsWVLDLQRRYNASFSIQGKPRalIYNTYQAYLQSTPRTLASHLAVSQKESFVLGVK 348
                 4455555************************************************98887776666********************************* PP

                 EE--S-HHHHHHHHHHTT-S-SB-SSHHHHHHHHHHHHHHHH.........HTTTTEEEE.............EE-S-HHHHHHHHHHHHHT...T--G CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.........xxxxxxxxx.............xxxxxxxxxxxxxxxxxxx.xxxxxx RF
      Pro_dh 163 LVrGAYldsErkraqelgyespifdtkeeTDanYdavaelll.........enrdeiypa.............vAsHNaesvakalalaeel.gqekek 238
                 LVrGAYl+s+++           ++tk++TD +Yda+ae l+                 +             +AsHN+ sv+ka al +++ + +++ 
  EEA21792.1 349 LVRGAYLNSDPR--------EIFWTTKQKTDIAYDAIAECLMtrkyndivqP-------VnehvrdfsqanlvLASHNRASVEKARALRDDQtRRGEPM 432
                 ************........79********************9955555550.......44444444455555*******************99999** PP

                 GGEEEEEETTSSHHHHHHH......HHTTS-.................EEEEEEECEHHHHHHHHHHHHHHHH-TT-HHH CS
                 xxxxxxxxxxxxxxxxxxx......xxxxxx.................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      Pro_dh 239 sevefqqLlGMadnlsfal......akagyn.................vrkYlPvGpveevlpYLvRRleENtanssftr 295
                  e+ ++qL+GMad++s+ l      +    +                  +kYl++G+v+e+ +YL+RR +EN++++s+t+
  EEA21792.1 433 IEMVYGQLQGMADDISCPLvrqsvmT----AsrdhslgqqrphgespkPYKYLVWGTVGECTKYLLRRGHENRDAASRTK 508
                 *******************7655440....145566778899999999*****************************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (527 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       545  (0.0303977); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.40
# Mc/sec: 3918.07
//
Query:       EEA21793.1  [L=204]
Description: peptide methionine sulfoxide reductase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-63  212.4   0.7    4.1e-63  212.1   0.7    1.0  1  PMSR      Peptide methionine sulfoxide reductase
  ------ inclusion threshold ------
      0.034   14.3   0.0      0.052   13.7   0.0    1.2  1  KaiA      KaiA C-terminal domain


Domain annotation for each model (and alignments):
>> PMSR  Peptide methionine sulfoxide reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  212.1   0.7   4.5e-67   4.1e-63       1     152 [.      36     190 ..      36     191 .. 0.98

  Alignments for each domain:
  == domain 1  score: 212.1 bits;  conditional E-value: 4.5e-67
                 EEEEE-S-HHHHHHHHCTST....TEEEEEEEEESSS-SS--HHHHHTTTT--EEEEEEEEETTTS-HHHHHHHHHHTS-TT-SSEETTEESGGG--EE CS
        PMSR   1 eavlagGCFWgveklfeklk....GvlstevGYagGktenptYeevcsgktghaEavevvydpekvsleellelffeihDptqlnrqgnDvGtqYrsai 95 
                 +a++a+GCFWgve+l++k+     G+++++vGYagG++++ptY+ vcsg+tghaEa++v++dp+ v++++lle+f+++hDpt+++rqg DvGtqYrsai
  EEA21793.1  36 KATVAAGCFWGVEHLYRKHFgdgkGLIDAKVGYAGGHADSPTYRAVCSGNTGHAEALQVTFDPSIVTYRQLLEFFYRMHDPTTQDRQGPDVGTQYRSAI 134
                 589***************9877779************************************************************************** PP

                 EESSCCHHHHHHHHHHHHHTTHTTSSS---EEEEG-SEEE--CCCTTHHHH-TTS-- CS
        PMSR  96 yytneeqkevaeevleelqkkkalkkkivteieplkefykaeeyHqqYleknpegyc 152
                 ++++eeq ++a+e++++++k+ ++k++++t+i p++++++aeeyHq Yl++np+gy+
  EEA21793.1 135 FTHDEEQSKIAKEITDKVSKE-WFKQPVTTQIVPAGQWWDAEEYHQLYLHNNPSGYE 190
                 ********************9.**********************************7 PP

>> KaiA  KaiA C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   5.8e-06     0.052       8      73 ..     101     166 ..      99     180 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 5.8e-06
                 CEEE--GGGSCCCSTHHHHHHHHHHHHHHHHHHHHHCTSTTSSHHHHHHHHHHHHHHTT--HHHHH CS
        KaiA   8 vyykrdpkkflrnlskeekkelleelkseyreivleyfkddsevnqkidefvnkaffadlsvskil 73 
                 v y++  + f+r  +++ +++   ++ ++yr+ ++++ +++s++ ++i + v+k +f +   ++i+
  EEA21793.1 101 VTYRQLLEFFYRMHDPTTQDRQGPDVGTQYRSAIFTHDEEQSKIAKEITDKVSKEWFKQPVTTQIV 166
                 56777788899999999999999**********************************998888887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (204 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       580  (0.0323498); expected 358.6 (0.02)
Passed bias filter:                      531  (0.0296168); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.23s 00:00:00.68 Elapsed: 00:00:00.40
# Mc/sec: 1525.17
//
Query:       EEA21794.1  [L=204]
Description: peptide methionine sulfoxide reductase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-63  212.4   0.7    4.1e-63  212.1   0.7    1.0  1  PMSR      Peptide methionine sulfoxide reductase
  ------ inclusion threshold ------
      0.034   14.3   0.0      0.052   13.7   0.0    1.2  1  KaiA      KaiA C-terminal domain


Domain annotation for each model (and alignments):
>> PMSR  Peptide methionine sulfoxide reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  212.1   0.7   4.5e-67   4.1e-63       1     152 [.      36     190 ..      36     191 .. 0.98

  Alignments for each domain:
  == domain 1  score: 212.1 bits;  conditional E-value: 4.5e-67
                 EEEEE-S-HHHHHHHHCTST....TEEEEEEEEESSS-SS--HHHHHTTTT--EEEEEEEEETTTS-HHHHHHHHHHTS-TT-SSEETTEESGGG--EE CS
        PMSR   1 eavlagGCFWgveklfeklk....GvlstevGYagGktenptYeevcsgktghaEavevvydpekvsleellelffeihDptqlnrqgnDvGtqYrsai 95 
                 +a++a+GCFWgve+l++k+     G+++++vGYagG++++ptY+ vcsg+tghaEa++v++dp+ v++++lle+f+++hDpt+++rqg DvGtqYrsai
  EEA21794.1  36 KATVAAGCFWGVEHLYRKHFgdgkGLIDAKVGYAGGHADSPTYRAVCSGNTGHAEALQVTFDPSIVTYRQLLEFFYRMHDPTTQDRQGPDVGTQYRSAI 134
                 589***************9877779************************************************************************** PP

                 EESSCCHHHHHHHHHHHHHTTHTTSSS---EEEEG-SEEE--CCCTTHHHH-TTS-- CS
        PMSR  96 yytneeqkevaeevleelqkkkalkkkivteieplkefykaeeyHqqYleknpegyc 152
                 ++++eeq ++a+e++++++k+ ++k++++t+i p++++++aeeyHq Yl++np+gy+
  EEA21794.1 135 FTHDEEQSKIAKEITDKVSKE-WFKQPVTTQIVPAGQWWDAEEYHQLYLHNNPSGYE 190
                 ********************9.**********************************7 PP

>> KaiA  KaiA C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   5.8e-06     0.052       8      73 ..     101     166 ..      99     180 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 5.8e-06
                 CEEE--GGGSCCCSTHHHHHHHHHHHHHHHHHHHHHCTSTTSSHHHHHHHHHHHHHHTT--HHHHH CS
        KaiA   8 vyykrdpkkflrnlskeekkelleelkseyreivleyfkddsevnqkidefvnkaffadlsvskil 73 
                 v y++  + f+r  +++ +++   ++ ++yr+ ++++ +++s++ ++i + v+k +f +   ++i+
  EEA21794.1 101 VTYRQLLEFFYRMHDPTTQDRQGPDVGTQYRSAIFTHDEEQSKIAKEITDKVSKEWFKQPVTTQIV 166
                 56777788899999999999999**********************************998888887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (204 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       580  (0.0323498); expected 358.6 (0.02)
Passed bias filter:                      531  (0.0296168); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.44
# Mc/sec: 1387.46
//
Query:       EEA21795.1  [L=204]
Description: peptide methionine sulfoxide reductase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-63  212.4   0.7    4.1e-63  212.1   0.7    1.0  1  PMSR      Peptide methionine sulfoxide reductase
  ------ inclusion threshold ------
      0.034   14.3   0.0      0.052   13.7   0.0    1.2  1  KaiA      KaiA C-terminal domain


Domain annotation for each model (and alignments):
>> PMSR  Peptide methionine sulfoxide reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  212.1   0.7   4.5e-67   4.1e-63       1     152 [.      36     190 ..      36     191 .. 0.98

  Alignments for each domain:
  == domain 1  score: 212.1 bits;  conditional E-value: 4.5e-67
                 EEEEE-S-HHHHHHHHCTST....TEEEEEEEEESSS-SS--HHHHHTTTT--EEEEEEEEETTTS-HHHHHHHHHHTS-TT-SSEETTEESGGG--EE CS
        PMSR   1 eavlagGCFWgveklfeklk....GvlstevGYagGktenptYeevcsgktghaEavevvydpekvsleellelffeihDptqlnrqgnDvGtqYrsai 95 
                 +a++a+GCFWgve+l++k+     G+++++vGYagG++++ptY+ vcsg+tghaEa++v++dp+ v++++lle+f+++hDpt+++rqg DvGtqYrsai
  EEA21795.1  36 KATVAAGCFWGVEHLYRKHFgdgkGLIDAKVGYAGGHADSPTYRAVCSGNTGHAEALQVTFDPSIVTYRQLLEFFYRMHDPTTQDRQGPDVGTQYRSAI 134
                 589***************9877779************************************************************************** PP

                 EESSCCHHHHHHHHHHHHHTTHTTSSS---EEEEG-SEEE--CCCTTHHHH-TTS-- CS
        PMSR  96 yytneeqkevaeevleelqkkkalkkkivteieplkefykaeeyHqqYleknpegyc 152
                 ++++eeq ++a+e++++++k+ ++k++++t+i p++++++aeeyHq Yl++np+gy+
  EEA21795.1 135 FTHDEEQSKIAKEITDKVSKE-WFKQPVTTQIVPAGQWWDAEEYHQLYLHNNPSGYE 190
                 ********************9.**********************************7 PP

>> KaiA  KaiA C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   5.8e-06     0.052       8      73 ..     101     166 ..      99     180 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 5.8e-06
                 CEEE--GGGSCCCSTHHHHHHHHHHHHHHHHHHHHHCTSTTSSHHHHHHHHHHHHHHTT--HHHHH CS
        KaiA   8 vyykrdpkkflrnlskeekkelleelkseyreivleyfkddsevnqkidefvnkaffadlsvskil 73 
                 v y++  + f+r  +++ +++   ++ ++yr+ ++++ +++s++ ++i + v+k +f +   ++i+
  EEA21795.1 101 VTYRQLLEFFYRMHDPTTQDRQGPDVGTQYRSAIFTHDEEQSKIAKEITDKVSKEWFKQPVTTQIV 166
                 56777788899999999999999**********************************998888887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (204 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       580  (0.0323498); expected 358.6 (0.02)
Passed bias filter:                      531  (0.0296168); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.24s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 1467.33
//
Query:       EEA21796.1  [L=1004]
Description: kinesin family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
   5.1e-118  393.8   0.0   1.1e-117  392.7   0.0    1.6  1  Kinesin      Kinesin motor domain
    5.3e-27   94.6   2.0    6.3e-27   94.4   0.0    2.2  3  Microtub_bd  Microtubule binding
     0.0024   18.1   4.3     0.0061   16.8   4.3    1.6  1  Herpes_UL14  Herpesvirus UL14-like protein
  ------ inclusion threshold ------
      0.012   15.8   0.0      0.059   13.5   0.0    2.3  1  AAA_33       AAA domain
      0.094   13.1   0.0         18    5.8   0.0    3.4  3  DUF760       Protein of unknown function (DUF760)


Domain annotation for each model (and alignments):
>> Kinesin  Kinesin motor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  392.7   0.0  3.1e-121  1.1e-117      23     333 .]      77     380 ..      15     380 .. 0.90

  Alignments for each domain:
  == domain 1  score: 392.7 bits;  conditional E-value: 3.1e-121
                 TCTCEEEEEEEEECTTSCEEEEESEEEETTS-HHHHHHHHHHHHHHHHHTTSEEEEEEEESTTSSHHHHHTBCTTTSBSHHHHHHHHHHHHHHHCTTTH CS
     Kinesin  23 ekkeeekkskkenkeeeekkfkFdkvfdeeatqeevyeetakplvesvleGynatifaYGqtgsGKTyTmegkeeeeeGiipraleelFesikkekeek 121
                   ++ +++   + k+ ++++f+Fd++fd ++tq+evye t+++l++svl+Gynat+faYG+tg+GKT+T++g+  +++Gii+ +++elFe+i+++kee 
  EEA21796.1  77 PVQKFSRSVVPNGKRVKDQTFAFDRIFDGNTTQAEVYEATTRNLLDSVLDGYNATVFAYGATGCGKTHTITGT-AQQPGIIFLTMQELFERIEERKEE- 173
                 45556666677788999*******************************************************9.999*****************9988. PP

                 EEEEEEEEEEEEEETTEEEETTSTTTTSTSSEBEEEECTTSCCEEETTS--EEESSHHHHHHHHHHHHHHHTSTTSSCTSHHCCSEEEEEEEEEEEETT CS
     Kinesin 122 ekefsvkvsylEiYneeiyDLLeskkskkkkklkiredskkgevyvkgltevevksaeevlellekgeknrkvaetklneeSSRSHavftitleqknlk 220
                  k +++++sylEiYne+i+DLL +   +++k l +red+++  v v+gl++++ ++++ev++++++g++ r+++ t++n++SSRSHav++i++ qk+++
  EEA21796.1 174 -KVTEISLSYLEIYNETIRDLLVTG--DNRKGLMLREDANQA-VSVAGLSSHHPQNVQEVMDMIMRGNECRTMSPTEANATSSRSHAVLQINIAQKDRN 268
                 .889*******************99..68889********86.******************************************************** PP

                 TTTCEEEEEEEEEEEEEEECCCHHHHSSTCHHHHHHHHHHHHHHHHHHHHHHHHHHTCCTSTSCGGGSHHHHHTGGGHSSSSEEEEEEEE-TBGGGHHH CS
     Kinesin 221 eeteekvkisklnLvDLAGsErasktgaaegerlkEaaniNkSLlaLgrvisaLaekkkskhipYRdSkLTrlLqdsLgGnsktlmivtvspssenlee 319
                 ++ +e  ++++l+++DLAGsEras+t++ +gerl+E+aniNkSLlaLg++i+aL++++k++hipYR+SkLTrlL+ sLgGn++t+miv+vspss++++e
  EEA21796.1 269 ADVNEPLTMATLSIIDLAGSERASATRN-RGERLQEGANINKSLLALGSCINALCDPRKRNHIPYRNSKLTRLLKFSLGGNCRTVMIVCVSPSSQHFDE 366
                 *99999*********************6.7999****************************************************************** PP

                 HHHHHHHHHHHCTT CS
     Kinesin 320 tlstlkfaerakei 333
                 t +tl++a+rak+i
  EEA21796.1 367 TQNTLRYANRAKNI 380
                 ************98 PP

>> Microtub_bd  Microtubule binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.4   0.0   1.7e-30   6.3e-27      43     149 .]      83     194 ..      10     194 .. 0.88
   2 ?   -2.5   0.3       1.2   4.3e+03      44      56 ..     414     426 ..     347     461 .. 0.55
   3 ?   -3.5   0.0       2.5     9e+03      48      80 ..     514     551 ..     487     556 .. 0.64

  Alignments for each domain:
  == domain 1  score: 94.4 bits;  conditional E-value: 1.7e-30
                  T........TTTEEEE-SEEEECTTHCCCCCCC.CHHHHHHHHTT--EEEEEEES................ST-HCHHHHHHHHHHCCTSCCCCEEEE CS
  Microtub_bd  43 e.....eekkkkkefsFdrvfeseseqeevfee.isqlvqsaldgynvcifaygqTGsGKtyTmegeeeeagmipraveeifetiselkekgwkyeie 134
                  +      ++ k+++f Fdr+f+ +++q+ev+e  ++ l++s+ldgyn ++fayg TG GKt+T++g+ +++g i  +++e+fe i+e+k +++  ei+
   EEA21796.1  83 RsvvpnGKRVKDQTFAFDRIFDGNTTQAEVYEAtTRNLLDSVLDGYNATVFAYGATGCGKTHTITGTAQQPGIIFLTMQELFERIEERK-EEKVTEIS 179
                  13444477899*******************9862579***************************************************5.677889** PP

                  EEEEEEESS-EEETT CS
  Microtub_bd 135 lqfveiynekvqDlL 149
                  l+++eiyne+++DlL
   EEA21796.1 180 LSYLEIYNETIRDLL 194
                  **************8 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 1.2
                  ...TTTEEEE-SE CS
  Microtub_bd  44 eekkkkkefsFdr 56 
                   ++k+ ++  F +
   EEA21796.1 414 AQQKQYESIAFAK 426
                  2233333333444 PP

  == domain 3  score: -3.5 bits;  conditional E-value: 2.5
                  TTEEEE-SEEEECTT....HCCCCCCCCHHHHHHHH.T CS
  Microtub_bd  48 kkkefsFdrvfeses....eqeevfeeisqlvqsal.d 80 
                  ++ +++F++ +++++     +  + + i+ql +  + d
   EEA21796.1 514 ENTRHHFNQRISKNNwdraINTALEHGIQQLKDFEIsD 551
                  56677788777777755555556666666666666545 PP

>> Herpes_UL14  Herpesvirus UL14-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   4.3   1.7e-06    0.0061      30     125 ..     357     456 ..     352     476 .. 0.84

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 1.7e-06
  Herpes_UL14  30 vstqdPaFveaFtaAkeaeedlkaqlrsdaRlesvrrkikriqakveeqaelrsiLkanRrylsp....kllerldatedkllekedsLeeavaelnd 123
                  vs++  +F e     + a+ + ++q ++   +  v+r++k+   k++eq++l ++Lka+ +  ++    k++++ +++e  + e   +L +a +++  
   EEA21796.1 357 VSPSSQHFDETQNTLRYANRAKNIQTKVTRNVYNVNRHVKDFLVKIDEQMALINELKAQQKQYESiafaKFKKQTEKKEAMVRESVTRLRNAYENAAT 454
                  7777888888888889999**************************************998866653333788888888889999*******9999844 PP

  Herpes_UL14 124 el 125
                  e 
   EEA21796.1 455 ER 456
                  33 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   1.7e-05     0.059       2      66 ..     132     193 ..     132     280 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 1.7e-05
      AAA_33   2 vllvGlpGsGKstlaerllkklgavllssdtlrrrlfgtdqqsktdytrvldrlyqilnelarka 66 
                 v+  G+ G+GK++ +++ +++ g ++l+  +l++r++++++++    t+++ +  +i ne++r+ 
  EEA21796.1 132 VFAYGATGCGKTHTITGTAQQPGIIFLTMQELFERIEERKEEKV---TEISLSYLEIYNETIRDL 193
                 5678********************************98655443...334444444445555444 PP

>> DUF760  Protein of unknown function (DUF760)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0     0.005        18       1      30 [.     162     231 ..     162     260 .. 0.86
   2 ?    2.9   0.1     0.041   1.5e+02      14      51 ..     487     525 ..     407     532 .. 0.81
   3 ?   -2.0   0.1       1.4   4.9e+03      43      65 ..     608     630 ..     563     639 .. 0.64

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.005
      DUF760   1 dLlryirslkpeevael........................................sephspevleaik 30 
                 +L+++i++ k+e+v+e+                                        s+ h + v+e++ 
  EEA21796.1 162 ELFERIEERKEEKVTEIslsyleiynetirdllvtgdnrkglmlredanqavsvaglSSHHPQNVQEVMD 231
                 5999*************99999999999999999999999999999999999988888888888888886 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.041
      DUF760  14 vaelsephspevleaikehvsgllgsle.pslqfqtliq 51 
                  a+ ++ +  e l+ai++  +g+l +le ++ +f++ i+
  EEA21796.1 487 CASCESKTPMENLQAIRKSAQGILFELEnTRHHFNQRIS 525
                 344488999999***************999999997765 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 1.4
      DUF760  43 slqfqtliqisrdklaqLlawsm 65 
                 +l   + +q+ ++ l ++l +++
  EEA21796.1 608 QLTEAEAVQVGKKILHKMLTSCI 630
                 22223566666666666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1004 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1564  (0.087233); expected 358.6 (0.02)
Passed bias filter:                      569  (0.0317363); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.80u 0.30s 00:00:01.10 Elapsed: 00:00:00.44
# Mc/sec: 6796.88
//
Query:       EEA21797.1  [L=152]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (152 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       442  (0.0246528); expected 358.6 (0.02)
Passed bias filter:                      391  (0.0218082); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.37u 0.27s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 1117.46
//
Query:       EEA21798.1  [L=206]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00024   21.5   1.2    0.00039   20.8   1.2    1.4  1  Tim17     Tim17/Tim22/Tim23/Pmp24 family


Domain annotation for each model (and alignments):
>> Tim17  Tim17/Tim22/Tim23/Pmp24 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8   1.2   2.2e-08   0.00039       5      94 ..      46     149 ..      43     171 .. 0.82

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 2.2e-08
       Tim17   5 tglsgvlGallGavfglvkgsrradtp.............apskerlreglrsvgkrgpslGknfgvvgglysgiecaleklRg.kediwnsvaAGalt 89 
                 +++++ +G+++Ga  g++k++++  ++             +  k +  +++   +  g++lG ++gv ++ + ++e +++ +R+ + d++ +v+AG+  
  EEA21798.1  46 AFTAFSVGLGVGANHGARKAAYQFRAEnahrfpttstgwfQYHKTKNYKAIVGGVFDGFRLGTRLGVGAMAFVLFEETVDCARHdRRDFLSTVIAGLSF 144
                 789*******************999878888888888887666666777777778899*************************7799*********988 PP

       Tim17  90 Gallr 94 
                  +++ 
  EEA21798.1 145 SGIYS 149
                 88874 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (206 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       346  (0.0192983); expected 358.6 (0.02)
Passed bias filter:                      317  (0.0176809); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.37u 0.22s 00:00:00.59 Elapsed: 00:00:00.35
# Mc/sec: 1760.00
//
Query:       EEA21799.1  [L=925]
Description: cyclic nucleotide-binding domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-36  124.6   0.0    1.2e-21   76.6   0.0    2.6  2  cNMP_binding   Cyclic nucleotide-binding domain
    2.2e-35  122.5   4.5    2.2e-35  122.5   4.5    2.1  2  cNMPbd_u2      Unstructured region on cNMP-binding protein
    9.8e-11   41.7   0.1       0.16   12.4   0.2    6.5  6  LRR_4          Leucine Rich repeats (2 copies)
      9e-08   31.9   0.8      9e-08   31.9   0.8    2.0  2  F-box-like     F-box-like
    2.6e-07   30.1   7.7        2.3    8.5   0.0    8.4  9  LRR_6          Leucine Rich repeat
    4.6e-06   26.4   4.1    1.3e-05   24.9   1.2    3.0  2  F-box          F-box domain
  ------ inclusion threshold ------
       0.17   12.2   1.6         19    5.6   0.3    3.8  3  SAM_Ste50p     Ste50p, sterile alpha motif
        1.3    9.2   6.7        1.2    9.3   3.6    2.5  2  Colipase-like  Colipase-like
        2.8    8.9  16.8         18    6.3   0.0    7.4  9  LRR_1          Leucine Rich Repeat


Domain annotation for each model (and alignments):
>> cNMP_binding  Cyclic nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.6   0.0   5.9e-25   1.2e-21       5      86 ..      87     165 ..      83     168 .. 0.96
   2 !   45.4   0.0   3.1e-15   6.3e-12       1      88 [.     285     385 ..     285     386 .. 0.83

  Alignments for each domain:
  == domain 1  score: 76.6 bits;  conditional E-value: 5.9e-25
                   -TT-EEE-TTSB-SEEEEEEES-EEEEEEETTS.EEEEEEE-TTEEESHHHHHHTS--SSEEEESSTEEEEEEEHHHHHHHH CS
  cNMP_binding   5 kagevifrqGdpadslyivlsGevrvyrlsedgkevvlavlgpGdlfGelalltgeprtatvvAltdsellalprddflell 86 
                   +a+++i+++Gd+a+ +y +++G v+v  +s+dg++ v a+l+pG++fGe+++l + prtat++A++++ l++l+++df+++l
    EEA21799.1  87 AANDYIVTEGDEAKAMYWLVRGAVAV--TSRDGES-VHAELKPGAFFGEIGVLMDRPRTATIIARSRCLLVVLTKEDFRKIL 165
                   79************************..9****88.9****************99*************************97 PP

  == domain 2  score: 45.4 bits;  conditional E-value: 3.1e-15
                   EEEE-TT-EEE-TTSB-SEEEEEEES-EEEE.............EEETTS.EEEEEEE-TTEEESHHHHH.HTS--SSEEEESSTEEEEEEEHHHHH CS
  cNMP_binding   1 rrsfkagevifrqGdpadslyivlsGevrvy.............rlsedgkevvlavlgpGdlfGelall.tgeprtatvvAltdsellalprddfl 83 
                   +rs+++ + i+rq+  ++++y++++Gev+v               ++++g e v a+l++G++fGe+  l    +rtatv+++t +e+l+l+ d + 
    EEA21799.1 285 PRSYPPFTDIIRQDSLGREIYFIVRGEVEVLnenrdsefrkdseDQASHGVE-VKARLRQGQYFGEIVSLsLTPRRTATVRSVTSVECLMLSGDVLA 380
                   589***************************9888888887444333333333.5559*********888855466********************** PP

                   HHHHH CS
  cNMP_binding  84 ellqq 88 
                   e++q+
    EEA21799.1 381 EFWQK 385
                   99986 PP

>> cNMPbd_u2  Unstructured region on cNMP-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   1.5       2.6   5.2e+03      93     131 ..       2      45 ..       1      59 [. 0.62
   2 !  122.5   4.5   1.1e-38   2.2e-35       1     139 [.     390     523 ..     390     542 .. 0.78

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 2.6
   cNMPbd_u2  93 RsrsRRgSl......APptpessresspts..keessssssetssP.k 131
                 R r+RR+S       A p+pe+ +     +  +++ + ++++ +sP +
  EEA21799.1   2 R-RQRRSSSgasskaAAPIPEAVS-LI--HsfDSALNPNRPARPSPlA 45 
                 4.4488887777777777777722.22..1235777888888888833 PP

  == domain 2  score: 122.5 bits;  conditional E-value: 1.1e-38
   cNMPbd_u2   1 irsqVEetAreRlktasdeDvemadaesstptssieelaiad.lkktsarrkslpevtftepskldspk...seddeevlePsDPDPFLsvdldnlRsr 95 
                 +r+q+E tA++Rl++++d+Dv mada +  pt++i++l+i+d lk ts+rrks+p vt+te+  ld+++    +++++vl+PsDPDPFL+++ldn++ +
  EEA21799.1 390 LRQQIELTAKKRLESTTDTDVLMADATD--PTPPINQLTIDDkLKVTSRRRKSMPLVTLTES-VLDNTHqanGDQEAPVLSPSDPDPFLNIGLDNVKFK 485
                 69***********************866..555*********99*****************9.6777666678999*********************** PP

   cNMPbd_u2  96 sRRgSlAPptpes......sressptskeessssssetssPklkskhslt 139
                 sRRgS+  ++p++      s           ++++++++ P  +s+++++
  EEA21799.1 486 SRRGSVGIIVPRDtanvesS-----------RQTTPTEPRP-GSSFKAIS 523
                 ************93333222...........3344444444.12222222 PP

>> LRR_4  Leucine Rich repeats (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0         9   1.8e+04       4      14 ..     588     600 ..     587     602 .. 0.66
   2 ?    1.9   0.0      0.16   3.2e+02       2      12 ..     668     678 ..     661     686 .. 0.67
   3 ?    5.6   0.0     0.012        23      10      34 ..     707     736 ..     703     740 .. 0.75
   4 ?    4.5   0.0     0.026        52       4      38 ..     755     794 ..     752     799 .. 0.73
   5 !   12.4   0.2   8.2e-05      0.16       1      33 [.     805     841 ..     805     847 .. 0.83
   6 !    7.7   0.0    0.0024       4.8       3      36 ..     860     897 ..     859     902 .. 0.83

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 9
                 -EEE--.SS.--- CS
       LRR_4   4 evLdLs.nN.qlt 14 
                 + LdLs  N ++t
  EEA21799.1 588 RDLDLSvYNrKVT 600
                 5588888774566 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.16
                 S--EEE--SS- CS
       LRR_4   2 nLevLdLsnNq 12 
                  L+++dLsn++
  EEA21799.1 668 GLQEVDLSNCR 678
                 56666666662 PP

  == domain 3  score: 5.6 bits;  conditional E-value: 0.012
                 SS---.E-S-HH....H-TT--EEE-.-S- CS
       LRR_4  10 nNqlt.diplle....klpnLkeLdLsgNn 34 
                  N+l+ +i+  +    ++p+Lk+L+Ls + 
  EEA21799.1 707 KNNLKpTIQTAAgavyGCPQLKKLTLSYCK 736
                 68899899994445658*********9884 PP

  == domain 4  score: 4.5 bits;  conditional E-value: 0.026
                 -EEE--SS.---E-S-.HH...H-TT--EEE-.-S----- CS
       LRR_4   4 evLdLsnN.qltdipl.le...klpnLkeLdLsgNnlitd 38 
                 e +dL  +  +td ++  +   ++++L++L L +++++td
  EEA21799.1 755 EQVDLTRCtTITDQGFqYWgnaQFTKLRKLCLADCTYLTD 794
                 55677744378988886225567*******9999999987 PP

  == domain 5  score: 12.4 bits;  conditional E-value: 8.2e-05
                 SS--EEE--.SS---E-S-..HH.H-TT--EEE-.-S CS
       LRR_4   1 pnLevLdLs.nNqltdipl..le.klpnLkeLdLsgN 33 
                 +nL++LdLs  + l+d     l+ ++p+L +L++s++
  EEA21799.1 805 KNLQELDLSfCCALSDTATevLAlQCPQLLKLNMSFC 841
                 79*******5569**8666784456*********876 PP

  == domain 6  score: 7.7 bits;  conditional E-value: 0.0024
                 --EEE--SS.---E-S-HH...H-TT--EEE-.-S--- CS
       LRR_4   3 LevLdLsnN.qltdiplle...klpnLkeLdLsgNnli 36 
                 L++L+ +++ ++t i+  +   ++ nL +L++s++ ++
  EEA21799.1 860 LQELSVRGCvRVTGIGVEAvadGCQNLSYLNVSQCKNL 897
                 89999999999******555557*********998555 PP

>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.9   0.8   4.5e-11     9e-08       3      45 ..     548     590 ..     547     593 .. 0.90
   2 ?   -3.7   0.1       6.1   1.2e+04      20      28 ..     673     681 ..     669     682 .. 0.81

  Alignments for each domain:
  == domain 1  score: 31.9 bits;  conditional E-value: 4.5e-11
  F-box-like   3 rLPdEiLlqIFsyLppsdLlrlalVCrrWrrvaldtplLWrrl 45 
                  LPd +L++IF+yL++  Llrl++VC +W  +    p L r l
  EEA21799.1 548 FLPDNVLVRIFEYLELHHLLRLRAVCAHWSKILTESPTLCRDL 590
                 59******************************98888886666 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 6.1
  F-box-like  20 dLlrlalVC 28 
                 dL++++ V+
  EEA21799.1 673 DLSNCRKVS 681
                 9****9997 PP

>> LRR_6  Leucine Rich repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       1.9   3.8e+03      14      21 ..     626     633 ..     618     636 .. 0.69
   2 ?    1.2   0.0      0.25     5e+02       4      17 ..     668     682 ..     665     683 .. 0.83
   3 ?    4.7   0.0     0.019        37       2      20 ..     724     743 ..     723     747 .. 0.85
   4 ?    2.7   0.0     0.082   1.6e+02       5      19 ..     754     769 ..     751     771 .. 0.88
   5 ?   -2.2   0.0       3.1   6.2e+03       3      17 ..     779     794 ..     779     797 .. 0.86
   6 !    8.5   0.0    0.0012       2.3       4      18 ..     806     821 ..     804     827 .. 0.87
   7 ?    1.9   0.0      0.15   2.9e+02       2      14 ..     830     842 ..     829     854 .. 0.78
   8 ?    4.2   0.0     0.028        56       5      24 .]     860     880 ..     856     880 .. 0.92
   9 ?    1.6   0.1      0.19   3.7e+02       2      14 ..     883     895 ..     882     899 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 1.9
       LRR_6  14 dIgDeGae 21 
                 +I+DeG +
  EEA21799.1 626 HITDEGFS 633
                 39***955 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.25
       LRR_6   4 hLteLdLsgNd.IgD 17 
                  L+e+dLs +  ++D
  EEA21799.1 668 GLQEVDLSNCRkVSD 682
                 599*******87777 PP

  == domain 3  score: 4.7 bits;  conditional E-value: 0.019
       LRR_6   2 nthLteLdLsgNd.IgDeGa 20 
                 ++ L++L Ls+++ ++D  +
  EEA21799.1 724 CPQLKKLTLSYCKhVTDRSM 743
                 789**********9999765 PP

  == domain 4  score: 2.7 bits;  conditional E-value: 0.082
       LRR_6   5 LteLdLsgNd.IgDeG 19 
                 ++ +dL+ +  I+D+G
  EEA21799.1 754 IEQVDLTRCTtITDQG 769
                 5779**********99 PP

  == domain 5  score: -2.2 bits;  conditional E-value: 3.1
       LRR_6   3 thLteLdLsgNd.IgD 17 
                 t+L++L L+++  ++D
  EEA21799.1 779 TKLRKLCLADCTyLTD 794
                 6899999999998887 PP

  == domain 6  score: 8.5 bits;  conditional E-value: 0.0012
       LRR_6   4 hLteLdLsgNd.IgDe 18 
                 +L+eLdLs+++ ++D 
  EEA21799.1 806 NLQELDLSFCCaLSDT 821
                 8**********99996 PP

  == domain 7  score: 1.9 bits;  conditional E-value: 0.15
       LRR_6   2 nthLteLdLsgNd 14 
                 ++ L +L++s+++
  EEA21799.1 830 CPQLLKLNMSFCG 842
                 88999******97 PP

  == domain 8  score: 4.2 bits;  conditional E-value: 0.028
       LRR_6   5 LteLdLsgNd.IgDeGaeaLa 24 
                 L+eL+++g+  +++ G+ea a
  EEA21799.1 860 LQELSVRGCVrVTGIGVEAVA 880
                 99****************986 PP

  == domain 9  score: 1.6 bits;  conditional E-value: 0.19
       LRR_6   2 nthLteLdLsgNd 14 
                 +++L +L++s ++
  EEA21799.1 883 CQNLSYLNVSQCK 895
                 89********997 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.9   1.2   6.5e-09   1.3e-05       6      44 ..     549     587 ..     549     590 .. 0.91
   2 ?   -0.1   0.1      0.46   9.2e+02      21      32 ..     672     683 ..     669     686 .. 0.81

  Alignments for each domain:
  == domain 1  score: 24.9 bits;  conditional E-value: 6.5e-09
                 S-HHHHHHHHHTS-HHHHHHHCTT-HHHHHHHTTHHHHH CS
       F-box   6 LPsevlrhILerLplsdllalrrVSkgwrilidsdrlwc 44 
                 LP+ vl  I+e+L+l +ll+lr V+ +w +++ +    c
  EEA21799.1 549 LPDNVLVRIFEYLELHHLLRLRAVCAHWSKILTESPTLC 587
                 9*****************************998776555 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.46
                 HHHHHHCTT-HH CS
       F-box  21 sdllalrrVSkg 32 
                 +dl ++r+VS +
  EEA21799.1 672 VDLSNCRKVSDT 683
                 799******965 PP

>> SAM_Ste50p  Ste50p, sterile alpha motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0      0.85   1.7e+03      41      57 ..     669     685 ..     657     691 .. 0.83
   2 ?    2.2   0.0       0.1   2.1e+02      41      58 ..     727     744 ..     721     748 .. 0.89
   3 ?    5.6   0.3    0.0097        19      41      57 ..     781     797 ..     775     805 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.85
                 HHHHHHHHHHHCTTS-H CS
  SAM_Ste50p  41 LseltLqDCkeLcdddl 57 
                 L+e+ L +C+ ++d  l
  EEA21799.1 669 LQEVDLSNCRKVSDTLL 685
                 9*********9999766 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.1
                 HHHHHHHHHHHCTTS-HH CS
  SAM_Ste50p  41 LseltLqDCkeLcdddlk 58 
                 L+ ltL  Ck ++d +++
  EEA21799.1 727 LKKLTLSYCKHVTDRSMH 744
                 899***********9986 PP

  == domain 3  score: 5.6 bits;  conditional E-value: 0.0097
                 HHHHHHHHHHHCTTS-H CS
  SAM_Ste50p  41 LseltLqDCkeLcdddl 57 
                 L  l+L+DC  L+d  +
  EEA21799.1 781 LRKLCLADCTYLTDHAI 797
                 889***********876 PP

>> Colipase-like  Colipase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.1       1.6   3.2e+03      50      65 ..     724     739 ..     708     763 .. 0.78
   2 ?    9.3   3.6   0.00058       1.2       9      89 ..     780     874 ..     775     874 .. 0.62

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 1.6
  Colipase-like  50 ClklrkpagevCqshk 65 
                    C +l+k+ + +C++  
     EEA21799.1 724 CPQLKKLTLSYCKHVT 739
                    7777888888887654 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.00058
  Colipase-like   9 klrklngveCskksEcksqcClkn.....seslekfC.....kpksliflqClklrkpagevCqshke.....clsqcclkLrelseqrClkrtel 89 
                    klrkl    C   ++     Cl+n     +e   +fC     ++ + ++lqC +l k++  +C s  +      ls + l L+els + C++ t++
     EEA21799.1 780 KLRKLCLADCTYLTDHA-IVCLTNaaknlQELDLSFCcalsdTATEVLALQCPQLLKLNMSFCGSAVSdpslrSLSLHLLLLQELSVRGCVRVTGI 874
                    56666666665555432.234433110003334457753322346789***************8865422222567899999**********9875 PP

>> LRR_1  Leucine Rich Repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.1         9   1.8e+04      11      20 ..      64      73 ..      59      74 .. 0.73
   2 ?    0.6   0.0      0.72   1.4e+03       4      20 ..     618     632 ..     618     637 .. 0.71
   3 ?    2.1   0.0      0.23   4.6e+02       2      11 ..     669     678 ..     668     689 .. 0.83
   4 ?    0.8   0.0      0.62   1.2e+03       1      14 [.     726     737 ..     726     747 .. 0.76
   5 ?   -1.9   0.1       4.6   9.2e+03       1      10 [.     780     789 ..     780     794 .. 0.90
   6 ?    6.3   0.0    0.0092        18       1      11 [.     806     816 ..     806     831 .. 0.90
   7 ?   -1.0   0.2       2.4   4.7e+03       2      13 ..     833     846 ..     832     858 .. 0.60
   8 ?   -1.8   0.0       4.4   8.8e+03       2      11 ..     860     869 ..     859     877 .. 0.84
   9 ?    2.7   0.1      0.14   2.8e+02       1      16 [.     885     898 ..     885     906 .. 0.83

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 9
       LRR_1 11 pllglppnsf 20
                pl++ +p+sf
  EEA21799.1 64 PLFQSTPDSF 73
                5799999998 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.72
       LRR_1   4 hLdLsnnpllglppnsf 20 
                 ++d++n++  +++++ f
  EEA21799.1 618 YIDINNCF--HITDEGF 632
                 589*9**9..5555555 PP

  == domain 3  score: 2.1 bits;  conditional E-value: 0.23
       LRR_1   2 LrhLdLsnnp 11 
                 L++ dLsn++
  EEA21799.1 669 LQEVDLSNCR 678
                 99*******8 PP

  == domain 4  score: 0.8 bits;  conditional E-value: 0.62
       LRR_1   1 nLrhLdLsnnpllg 14 
                 +L++L Ls++   +
  EEA21799.1 726 QLKKLTLSYCK--H 737
                 59********8..4 PP

  == domain 5  score: -1.9 bits;  conditional E-value: 4.6
       LRR_1   1 nLrhLdLsnn 10 
                 +Lr+L L ++
  EEA21799.1 780 KLRKLCLADC 789
                 7******998 PP

  == domain 6  score: 6.3 bits;  conditional E-value: 0.0092
       LRR_1   1 nLrhLdLsnnp 11 
                 nL++LdLs ++
  EEA21799.1 806 NLQELDLSFCC 816
                 8*********9 PP

  == domain 7  score: -1.0 bits;  conditional E-value: 2.4
       LRR_1   2 LrhLdLsnnpl..l 13 
                 L +L++s +    +
  EEA21799.1 833 LLKLNMSFCGSavS 846
                 56799999986431 PP

  == domain 8  score: -1.8 bits;  conditional E-value: 4.4
       LRR_1   2 LrhLdLsnnp 11 
                 L++L ++++ 
  EEA21799.1 860 LQELSVRGCV 869
                 89******96 PP

  == domain 9  score: 2.7 bits;  conditional E-value: 0.14
       LRR_1   1 nLrhLdLsnnpllglp 16 
                 nL +L++s++ +l  +
  EEA21799.1 885 NLSYLNVSQCKNL--Q 898
                 899*******974..3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (925 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       435  (0.0242624); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.72u 0.29s 00:00:01.01 Elapsed: 00:00:00.47
# Mc/sec: 5958.44
//
Query:       EEA21800.1  [L=676]
Description: hypothetical protein PMAA_055920 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.1e-06   26.3   7.0    1.1e-05   25.5   7.0    1.4  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.5   7.0   5.9e-10   1.1e-05       1      35 [.     304     340 ..     304     345 .. 0.92

  Alignments for each domain:
  == domain 1  score: 25.5 bits;  conditional E-value: 5.9e-10
                 SS-HHHHHCT---ST..SSSS-HHHHHCTHHHCCCCT CS
     Zn_clus   1 haCdnCrkkKvKCda..kkPaCsnCkklnleCtfyse 35 
                 haC++C+  K +C +  ++P+C +C+ ++  C++++ 
  EEA21800.1 304 HACNRCKLAKQRCTYtpGNPSCDKCAISGERCRYIDY 340
                 8********************************8765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (676 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2506  (0.139774); expected 358.6 (0.02)
Passed bias filter:                      642  (0.0358079); expected 358.6 (0.02)
Passed Vit filter:                        84  (0.00468515); expected 17.9 (0.001)
Passed Fwd filter:                        22  (0.00122706); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.90u 0.33s 00:00:01.23 Elapsed: 00:00:00.50
# Mc/sec: 4037.69
//
Query:       EEA21801.1  [L=792]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.9e-23   81.6   0.0    1.3e-22   79.5   0.1    2.1  2  Slx4      Slx4 endonuclease
  ------ inclusion threshold ------
      0.078   12.8   0.2       0.18   11.6   0.2    1.7  1  SAP       SAP domain


Domain annotation for each model (and alignments):
>> Slx4  Slx4 endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0      0.42   3.8e+03      23      38 ..      87     102 ..      86     111 .. 0.82
   2 !   79.5   0.1   1.5e-26   1.3e-22       4      60 ..     714     789 ..     711     790 .. 0.87

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.42
                 -EEHHHHHHHHHHH-G CS
        Slx4  23 PIvLedltawLntegl 38 
                 PIv e++t+ +++++ 
  EEA21801.1  87 PIVSEHFTQTARSGSS 102
                 9********9999855 PP

  == domain 2  score: 79.5 bits;  conditional E-value: 1.5e-26
                 HHHHHHT...............-HHHHHHHHTT--EEHHHHHHHHHHH-GGGG....GS-HHHHHHHHHHHT--EE CS
        Slx4   4 iteaiks...............dpslhekILlYePIvLedltawLnteglglk....evdpaelrewcdskgIcct 60 
                 i +ai+                + ++hekILlYePI+Led+++wLnteg+ l     ev+ a +r+wc+s+gIcct
  EEA21801.1 714 IARAIRLqtrpknlltngscppQLTWHEKILLYEPIILEDFATWLNTEGFALVsedrEVGVALVRTWCESQGICCT 789
                 666777777777777778888889************************77666**********************9 PP

>> SAP  SAP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.2     2e-05      0.18       2      30 ..     526     554 ..     525     557 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 2e-05
                 TT--HHHHHHHHHHTT--TTS-HHHHHHH CS
         SAP   2 skltVaeLKeeLkkrGLptsGkKaeLieR 30 
                 +  t  eL+++ k++GL+  G+++ Li+ 
  EEA21801.1 526 NGYTDVELRKKVKSYGLKAIGRRKRLIAL 554
                 67899******************999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (792 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1296  (0.0722851); expected 358.6 (0.02)
Passed bias filter:                      391  (0.0218082); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.73u 0.28s 00:00:01.01 Elapsed: 00:00:00.46
# Mc/sec: 5215.45
//
Query:       EEA21802.1  [L=193]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.8e-54  183.6   0.1    3.3e-54  183.4   0.1    1.0  1  CGI-121      Kinase binding protein CGI-121
  ------ inclusion threshold ------
      0.057   13.0   0.0      0.097   12.3   0.0    1.4  1  CAMP_factor  CAMP factor (Cfa)


Domain annotation for each model (and alignments):
>> CGI-121  Kinase binding protein CGI-121
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  183.4   0.1   3.6e-58   3.3e-54       1     162 []      23     190 ..      23     190 .. 0.95

  Alignments for each domain:
  == domain 1  score: 183.4 bits;  conditional E-value: 3.6e-58
                 EES-S-HHHHHHTHC..CHCTT-EEE-GGG---HHHHHHHHHHHHHHHHHS---SSSHHHHHHHHHSSSS-HHHHHHHHB--TT-S-EEEEEEESS.S- CS
     CGI-121   1 FknVknaaelrkqllskraeldfafldaslilskehllsAvlrallaaargklktktlhsEilfsLspnnnIgealkrfgisdkttsllvvkvsss.ea 98 
                 +k +kna++lr+qll ++ae+++af+das+i+s++h+l+Av+ra++++ +++l+++++hsEi++sL p+nnI++a++rfgi+d+t++llvvk+s s e+
  EEA21802.1  23 YKYLKNASFLREQLLTGNAEFQYAFIDASTIISRQHILAAVFRAINDYLNNRLRSHNVHSEIVVSLGPSNNIADAFRRFGITDSTKDLLVVKLSVSpEI 121
                 6789*****************************************************************************************99999* PP

                 -HHHHHHHHHHHS-SEEE--SH.HHHHH--HHHHHHHTT--.....TT---SSHHH.HHHHHHHHHHTX CS
     CGI-121  99 deeevlkslkevvegelvplee.eleeltdwkkikkiYklne...leeekeeevke.ledlvvsavalk 162
                 ++e+v k+l+++ve ++vp+++ ++++++d++ki+k+Ykln+   ++++ +++  + le l+++a+a++
  EEA21802.1 122 THESVAKHLESSVEATPVPFNDeTISSMSDLAKIRKLYKLNQpvsKSADGQDNPVKaLEPLILGAIAIR 190
                 *******************************************99444555555555**********97 PP

>> CAMP_factor  CAMP factor (Cfa)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   1.1e-05     0.097      38      86 ..      21      70 ..       3      98 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.1e-05
  CAMP_factor 38 eiekllktakelkealea.iakgkvtlydlksIlaRvellvdivdtikta 86
                  + k lk a  l+e+l +  a+ + +++d+++I++R ++l+++  +i+  
   EEA21802.1 21 ALYKYLKNASFLREQLLTgNAEFQYAFIDASTIISRQHILAAVFRAINDY 70
                 566889999999999876135557899********************864 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (193 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       482  (0.0268838); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 1351.14
//
Query:       EEA21803.1  [L=340]
Description: Bax Inhibitor family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.8e-33  114.5   8.8    8.9e-33  113.9   8.8    1.3  1  Bax1-I    Inhibitor of apoptosis-promoting Bax1
     0.0078   15.6   1.3      0.015   14.7   1.3    1.4  1  DUF963    Schizosaccharomyces pombe repeat of unknown functio


Domain annotation for each model (and alignments):
>> Bax1-I  Inhibitor of apoptosis-promoting Bax1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.9   8.8   9.9e-37   8.9e-33       1     207 []     117     332 ..     117     332 .. 0.83

  Alignments for each domain:
  == domain 1  score: 113.9 bits;  conditional E-value: 9.9e-37
      Bax1-I   1 raflrkvYgllalgllltalvaavvlsspaqlflslhivlflvvilaplalvflsls.aarlkkkssalalallllftlleGlslspillvytgaiilq 98 
                 r++l+ ++++++lgl++ a++a ++ +s+    ++l++   + v+ ++l++ ++ ++ ++++   ++ l++al+ +f + ++++lsp++++  +a++++
  EEA21803.1 117 RQYLNETFMHTGLGLGVIAIAARALHTSG--WSVRLMTSNPWAVVGLGLVASIGTMYgTMYTPPENYMLKYALWTGFNVTQAALLSPLMFLS-PALLAR 212
                 689********************999999..666666677777777777777555440444444444466*******************997.****** PP

      Bax1-I  99 aflltaaifgglslyalttkrdls.glggflfagligliiaslvnlFlp......ssalelai.s.....ylgvllfsglilyDtqkiierageygee. 183
                 a l+t++++g+++++++t+k++ + +lgg l+ag+ ++ +++++ l lp             + s     y+g+ +f g++lyD+qki+ +a + +e  
  EEA21803.1 213 AGLYTVGMMGSIAFVGATAKQEKYlYLGGPLLAGVAVVALSGFAPLVLPataartL------MwSeriwlYGGLAVFGGFTLYDIQKILYHA-RLAERg 304
                 *******************776666************************6554433......43455555*******************544.445558 PP

      Bax1-I 184 ....dailaalsLyldfinlFlslLril 207
                     d+++ ++sL ldfin+F+++++il
  EEA21803.1 305 vvcrDPVNESVSLELDFINIFVRMVQIL 332
                 **************************97 PP

>> DUF963  Schizosaccharomyces pombe repeat of unknown function (DUF963)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   1.3   1.7e-06     0.015      11      34 ..      33      56 ..      32      57 .. 0.94

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.7e-06
      DUF963 11 TPvtsSTpVnsSTPItsSsvvnsS 34
                TP +sST+ + STP ++Ss++  S
  EEA21803.1 33 TPFKSSTAFKPSTPTRPSSILARS 56
                9*******************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (340 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       342  (0.0190752); expected 358.6 (0.02)
Passed bias filter:                      223  (0.0124379); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.30s 00:00:00.82 Elapsed: 00:00:00.50
# Mc/sec: 2061.00
//
Query:       EEA21804.1  [L=157]
Description: RNA binding protein (Rbm8A), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-15   56.2   0.0    3.3e-15   55.6   0.0    1.3  1  RRM_1     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom
      0.006   16.2   0.0     0.0088   15.6   0.0    1.2  1  RRM_5     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom
  ------ inclusion threshold ------
      0.071   13.2   0.0       0.11   12.5   0.0    1.3  1  RRM_3     RNA binding motif


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.6   0.0   5.5e-19   3.3e-15       4      69 ..      44     110 ..      41     111 .. 0.96

  Alignments for each domain:
  == domain 1  score: 55.6 bits;  conditional E-value: 5.5e-19
                 ESETTTSSHHHHHHHHHTTSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1   4 gnLppdvteeeLkelFskfGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrel 69 
                 +n++++++ee++ +lF ++G+ik+++l  d +tg  kg+a +e+ +  +A++A+ealng kl +++l
  EEA21804.1  44 TNIHEEASEEDVTDLFAEYGEIKNFNLNLDrRTGYVKGYALIEYSTLPEARSAIEALNGAKLLDQTL 110
                 79*********************************************************99998876 PP

>> RRM_5  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   1.5e-06    0.0088      11      96 ..      23     112 ..      13     116 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 1.5e-06
       RRM_5  11 svaatgspgaagvaegsVllVyglepdkvnldklFnlfclYgnvervkflktk.....ketalvqmgdasaveravqHLnnaklfgkrlev 96 
                 ++ +++   a    eg +++ ++++++ +  + +  lf+ Yg+++   +   +     k++al++ +   ++  a++ Ln+akl ++ l v
  EEA21804.1  23 EAKTQAGAVAVRSIEGWIIIATNIHEEASE-EDVTDLFAEYGEIKNFNLNLDRrtgyvKGYALIEYSTLPEARSAIEALNGAKLLDQTLSV 112
                 333333344445557888999999887665.6689**********998854322333389***************************9987 PP

>> RRM_3  RNA binding motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   1.8e-05      0.11       3      65 ..      40     108 ..      38     118 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.8e-05
                 EEEEEE-SSS--HHHHHHHCHCCS-ECEEEE-TTSSEEEEE......ESSHHHHHHHHHHHHHC-B-CC CS
       RRM_3   3 ilklsGlnkelsredikellsklgevayvdyekgdkegevr......Fkedeeakkalekateaklkik 65 
                 i+  + +++e s ed+ +l++++ge++  +++ +  +g+v+      + +  ea+ a+e++  akl  +
  EEA21804.1  40 IIIATNIHEEASEEDVTDLFAEYGEIKNFNLNLDRRTGYVKgyalieYSTLPEARSAIEALNGAKLLDQ 108
                 555555999***********************9999999865444447777788888888888866555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (157 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       416  (0.0232026); expected 358.6 (0.02)
Passed bias filter:                      352  (0.019633); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.45
# Mc/sec: 1059.72
//
Query:       EEA21805.1  [L=592]
Description: glycosyl hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.5e-23   83.2   0.0      1e-22   81.2   0.0    1.9  1  Glyco_hydro_76  Glycosyl hydrolase family 76


Domain annotation for each model (and alignments):
>> Glyco_hydro_76  Glycosyl hydrolase family 76
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.2   0.0   5.6e-27     1e-22     120     293 ..     198     405 ..     193     417 .. 0.90

  Alignments for each domain:
  == domain 1  score: 81.2 bits;  conditional E-value: 5.6e-27
                     HHHHHHHC.B-SCSCCS-BBSEC..ESS--SEEEHHHHHHHHHHHHHHHHHH.................--CHHHHHHHHHHHHHHHHSCSBTTT CS
  Glyco_hydro_76 120 vfntqasr.wdeetcgGGlrWqiftwnsgydyknsisngplfqlaarLaryt.................gnetYlewAekvwdWvedvglidded 196
                     +f+ +as+ wd++ c+GG+ W+   +     ykn+i n  +  +++ ++ y                   + +Yl  A + ++W++d+++   + 
      EEA21805.1 198 IFYDLASTgWDSKLCEGGMIWSP--YL--EPYKNAITNELFISASIGMYLYFtgdpisapfmpsdhyrvHDPSYLAAAVRSYQWLKDSNMT-GTG 287
                     677777777************65..55..45**************99999877999999999999999999******************97.999 PP

                     S-B-SEEE..........TTTCCEEEE---HHHHHHHHHHHHHHHHHHH--HHHHHHHHHHHHHH.HHHCEEC...........TTEEEEEE-TT CS
  Glyco_hydro_76 197 wlvyDgas..........vednctdinklqwtYnqGtylsgaaylynaTgdekWldrvkgllnat.lstffpd...........gnilyevacep 269
                     +l++Dg +           +++c  +n++ +tYnqG++lsg   l+ aTg + +l++ ++l++++ ++t +p+           g++l e ac +
      EEA21805.1 288 GLYADGFHihgykgvknpGTKKCDVLNPMVFTYNQGVILSGLRGLWLATGYQDYLEDGHELIQRViRATGWPKtnrrnwaglgrGGVL-EEACDS 381
                     *******999****99998999999***************************************99888888889********66666.66**** PP

                     STTCCTTHHHHHHHHHHHHHHHH. CS
  Glyco_hydro_76 270 sekcnnDqrsFkgilarwlaltaq 293
                     +++c +D ++Fkgi+++ l  + +
      EEA21805.1 382 HSNCSQDGHTFKGIFFHHLTEFCH 405
                     999**************8876554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (592 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       438  (0.0244297); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.66u 0.29s 00:00:00.95 Elapsed: 00:00:00.52
# Mc/sec: 3435.44
//
Query:       EEA21806.1  [L=100]
Description: ATPase inhibitor, mitochondrial precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.9e-26   91.7   0.9    3.4e-26   91.6   0.9    1.1  1  IATP       Mitochondrial ATPase inhibitor, IATP
     0.0043   17.3   2.7     0.0056   16.9   2.7    1.2  1  BLOC1_2    Biogenesis of lysosome-related organelles complex-
     0.0046   17.1   2.2     0.0059   16.7   2.2    1.1  1  TssO       Type VI secretion system, TssO
  ------ inclusion threshold ------
      0.015   15.8   0.5      0.018   15.5   0.5    1.3  1  DUF4140    N-terminal domain of unknown function (DUF4140)
      0.015   14.4   0.3      0.019   14.1   0.3    1.1  1  AdoHcyase  S-adenosyl-L-homocysteine hydrolase
      0.017   13.8   0.2      0.017   13.8   0.2    1.0  1  FapA       Flagellar Assembly Protein A
      0.052   14.0   0.5      0.069   13.6   0.5    1.2  1  NPV_P10    Nucleopolyhedrovirus P10 protein
      0.069   13.2   0.1       0.14   12.3   0.1    1.5  1  PKHD_C     PKHD-type hydroxylase C-terminal domain
       0.16   11.8   3.5       0.24   11.2   3.5    1.3  1  DivIC      Septum formation initiator


Domain annotation for each model (and alignments):
>> IATP  Mitochondrial ATPase inhibitor, IATP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.6   0.9   1.7e-29   3.4e-26       5      98 .]       6      93 ..       1      93 [. 0.92

  Alignments for each domain:
  == domain 1  score: 91.6 bits;  conditional E-value: 1.7e-29
        IATP  5 tlaktltasrpv.saasfsvaarrmgEgdsGapkgtGggGsireagdafgkrEaAsEeeyirqrekekLaeLkeklaeqkeHleeleeHieaitr 98
                +++++l+a++ +  ++sfsva+ rmg gd+Gap+g+ +       +d+f+krEaA+E+ y+r++e ekL+eLk kl+eq++Hl+el++Hi+++t+
  EEA21806.1  6 VARPLLRANQRLvATRSFSVASVRMGAGDTGAPRGAAA-------ADSFTKREAAQENLYVREKELEKLKELKSKLKEQRKHLDELDKHIDQLTK 93
                567788888887799******************98766.......9**********************************************997 PP

>> BLOC1_2  Biogenesis of lysosome-related organelles complex-1 subunit 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   2.7   2.8e-06    0.0056      42      79 ..      56      93 ..      44      94 .. 0.86

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 2.8e-06
     BLOC1_2 42 vaaslekkleklnekyeelqpylqqidqiekqvteLee 79
                ++   ek+lekl+e++ +l+++ +++d+++k++++L++
  EEA21806.1 56 NLYVREKELEKLKELKSKLKEQRKHLDELDKHIDQLTK 93
                5555689****************************985 PP

>> TssO  Type VI secretion system, TssO
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   2.2   2.9e-06    0.0059      38      78 ..      54      95 ..      46      99 .. 0.83

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 2.9e-06
        TssO 38 qekeil.lkelerkkkfeekqkelkkkvdsiykkIdsLkpev 78
                qe+    +kele+ k++++k ke++k++d+++k+Id+L++e+
  EEA21806.1 54 QENLYVrEKELEKLKELKSKLKEQRKHLDELDKHIDQLTKEQ 95
                455555689*****************************9987 PP

>> DUF4140  N-terminal domain of unknown function (DUF4140)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.5   0.5   8.9e-06     0.018      44      94 ..      44      94 ..      19      97 .. 0.88

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 8.9e-06
     DUF4140 44 agaatildvqvervpnreaeeeelkalraeleeledelaaledelaaaear 94
                a+++t  + + e+ + re+e e+lk+l+++l+e +++l++l++ ++ + ++
  EEA21806.1 44 ADSFTKREAAQENLYVREKELEKLKELKSKLKEQRKHLDELDKHIDQLTKE 94
                46678888888999999999999*********************9999876 PP

>> AdoHcyase  S-adenosyl-L-homocysteine hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.3   9.6e-06     0.019     228     282 ..      45      96 ..      40      98 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 9.6e-06
                 HHHHHHHHHHHHHHHTTSSS-SSEEE--CHHHHHHHHHCCCCCT-------HHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   AdoHcyase 228 asftnqvlaqielfkkekkyekkvyvlpkklDekvarlhleklgaklteltkeqa 282
                  sft+   aq +l+ +ek   +k++ l  kl e+  r hl++l+ ++++ltkeq 
  EEA21806.1  45 DSFTKREAAQENLYVREK-ELEKLKELKSKLKEQ--RKHLDELDKHIDQLTKEQG 96 
                 69*************766.66789********97..99***************95 PP

>> FapA  Flagellar Assembly Protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.2   8.5e-06     0.017     319     370 ..      48      98 ..       4     100 .] 0.68

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 8.5e-06
        FapA 319 elgtkteievgldepelkeklkeleeeleeleeeleklkkkikklpklkaek 370
                 +  ++ + ++ ++  +  eklkel+ +l+e +++l++l+k i++l k++  +
  EEA21806.1  48 TKREAAQENLYVR-EKELEKLKELKSKLKEQRKHLDELDKHIDQLTKEQGGE 98 
                 4444445555555.44556669999999999***************965544 PP

>> NPV_P10  Nucleopolyhedrovirus P10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.5   3.5e-05     0.069      22      62 ..      52      92 ..      42      94 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 3.5e-05
     NPV_P10 22 alqqqvddvqenlpdvtelnekLdaqsaqLaeletkvenIq 62
                a q+++   +++l++++el++kL +q + L+el++++++ +
  EEA21806.1 52 AAQENLYVREKELEKLKELKSKLKEQRKHLDELDKHIDQLT 92
                6667777778899**********************999875 PP

>> PKHD_C  PKHD-type hydroxylase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.1     7e-05      0.14       2      23 ..      76      98 ..      76     100 .] 0.88

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 7e-05
      PKHD_C  2 aqRalLfdLDqaIqrlraelg.d 23
                +qR+ L +LD++I +l++e+g +
  EEA21806.1 76 EQRKHLDELDKHIDQLTKEQGgE 98
                69*****************9944 PP

>> DivIC  Septum formation initiator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   3.5   0.00012      0.24      10      46 ..      58      94 ..      52      96 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00012
                XXXXXXXXHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
       DivIC 10 ifgkkgllaykqlkqeiaalqaelaklkaeneeLeae 46
                +  +k l ++k+lk++++++ ++l++l + +++L++e
  EEA21806.1 58 YVREKELEKLKELKSKLKEQRKHLDELDKHIDQLTKE 94
                5567788899999999999999999999999999988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (100 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2468  (0.137654); expected 358.6 (0.02)
Passed bias filter:                     1130  (0.0630264); expected 358.6 (0.02)
Passed Vit filter:                       175  (0.00976072); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.43u 0.29s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 718.08
//
Query:       EEA21807.1  [L=261]
Description: 14-3-3 family protein ArtA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.2e-105  351.9   5.6   1.5e-105  351.7   5.6    1.0  1  14-3-3    14-3-3 protein


Domain annotation for each model (and alignments):
>> 14-3-3  14-3-3 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  351.7   5.6  8.1e-110  1.5e-105       1     222 []       9     231 ..       9     231 .. 0.99

  Alignments for each domain:
  == domain 1  score: 351.7 bits;  conditional E-value: 8.1e-110
                 HHHHHHHCCHHHHHHHHHCHHHHCSS---HCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCTCC.HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC CS
      14-3-3   1 laklaeqaeryddmveymkkvvelkeeLskeernlLsvayKnvvgarRaswrvlssieqkeeske.ekkvelikeyrekiekeLkeiceevlelldktl 98 
                 laklaeqaery++mve mk v+++++eLs+eernlLsvayKnv+garRaswr+++sieqkeesk+ e++v+likeyr+kie+eL++ice++le+ldk+l
  EEA21807.1   9 LAKLAEQAERYEEMVENMKVVASSDQELSVEERNLLSVAYKNVIGARRASWRIVTSIEQKEESKGnESQVTLIKEYRQKIETELAKICEDILEVLDKHL 107
                 69**************************************************************9999******************************* PP

                 HCH.-SHHHHHHHHHHHHHHHHHHHCC--HHHHHHHHHHHHHHHHHHHHHHHTTTGCC-HHHHHHHHHHHHHHHCTT--HHHHHHHHHHHHHCCHCCCC CS
      14-3-3  99 ipkatseeskvfylkmkgDyyRYlaEfaegeekkeaaekakeaYeeAleiakkelqpthpirLglaLNySVflyeilnspekAcelakkafdeaiaeld 197
                 ip+a++ eskvfy+kmkgDy+RYlaEfa g+ +k +a+++ eaY++A+e+a+++l+pthpirLglaLN+SVf+yeilnsp++Ac+lak afd+aiaeld
  EEA21807.1 108 IPSAQTGESKVFYHKMKGDYHRYLAEFAIGDRRKASADASLEAYKAATEVAQTDLAPTHPIRLGLALNFSVFYYEILNSPDQACHLAKLAFDDAIAELD 206
                 *999*********************************************************************************************** PP

                 CS.TTTHHHHHHHHHHHHHHHHHHC CS
      14-3-3 198 elseesykdstlilqlLrdnltlWt 222
                 +lseesykdstli+qlLrdnltlWt
  EEA21807.1 207 TLSEESYKDSTLIMQLLRDNLTLWT 231
                 ************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (261 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1366  (0.0761894); expected 358.6 (0.02)
Passed bias filter:                      708  (0.0394891); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 1853.00
//
Query:       EEA21808.1  [L=173]
Description: bZIP transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-34  116.6   2.0    5.1e-34  116.1   2.0    1.3  1  DUF2205   Short coiled-coil protein
     0.0019   17.5   4.1     0.0025   17.2   4.1    1.1  1  DUF3450   Protein of unknown function (DUF3450)
  ------ inclusion threshold ------
      0.011   16.4   2.7      0.015   15.9   2.7    1.2  1  YabA      Initiation control protein YabA
      0.012   15.0   3.6      0.019   14.3   3.6    1.3  1  CASP_C    CASP C terminal
      0.024   14.5   0.1      0.049   13.6   0.1    1.5  1  RBD-FIP   FIP domain
       0.11   12.3   3.7       0.17   11.7   3.7    1.3  1  DivIC     Septum formation initiator
       0.11   12.6   3.3       0.25   11.6   3.3    1.6  1  JIP_LZII  JNK-interacting protein  leucine zipper II
       0.13   12.4   4.8       0.32   11.1   4.6    1.7  2  bZIP_1    bZIP transcription factor
       0.84   10.7   3.6        1.9    9.6   2.1    2.2  2  DUF5320   Family of unknown function (DUF5320)


Domain annotation for each model (and alignments):
>> DUF2205  Short coiled-coil protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.1   2.0   2.6e-37   5.1e-34       1      74 [.      89     165 ..      89     166 .. 0.98

  Alignments for each domain:
  == domain 1  score: 116.1 bits;  conditional E-value: 2.6e-37
     DUF2205   1 msprrnsedveklerearerLqqqakeLqssLqaLaervdeVkeehdKLesenrfLqqYIgdL...mstskvtqsts 74 
                 msprr+s+dve+l++ear++Lq+qak+Lq sLqaLa+r++eVk++hdKLesenr+Lq+YIg+L   +s+s++t++t+
  EEA21808.1  89 MSPRRDSADVERLGKEARQTLQEQAKTLQLSLQALAQRIEEVKNDHDKLESENRYLQDYIGSLtqtISKSEITSTTG 165
                 9*************************************************************************986 PP

>> DUF3450  Protein of unknown function (DUF3450)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   4.1   1.3e-06    0.0025      28      84 ..     102     158 ..      87     164 .. 0.89

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 1.3e-06
     DUF3450  28 avaaaaqsqkkidklddekqellaeyralkeeleslevyneqlerlvasqeqeiasl 84 
                   +a++  q++ + l+   q l+++++++k+  ++le +n++l++++ s+ q+i++ 
  EEA21808.1 102 GKEARQTLQEQAKTLQLSLQALAQRIEEVKNDHDKLESENRYLQDYIGSLTQTISKS 158
                 56789999********************************************99875 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.9   2.7   7.7e-06     0.015      11      69 ..     107     168 ..      99     173 .] 0.76

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 7.7e-06
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH...XXXXXXXXXXXXXXXXX CS
        YabA  11 eeleeqleelleeleelkeelaelleenaeLeleneklrerl...eeeekkekekkkelseg 69 
                 ++l+eq ++l+ +l++l ++++e+ +++++Le en+ l++ +   +++ +k++ ++++ +++
  EEA21808.1 107 QTLQEQAKTLQLSLQALAQRIEEVKNDHDKLESENRYLQDYIgslTQTISKSEITSTTGGKS 168
                 679999999*****************************999966533334444444444444 PP

>> CASP_C  CASP C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   3.6   9.6e-06     0.019     101     157 ..     107     163 ..     100     173 .] 0.77

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 9.6e-06
      CASP_C 101 aeLEeelrkqeetvsslraeiaslqkDNlkLYEkvRYlqsYnrgskas.tksssesss 157
                 + L+e+ ++ + +++ l + i+++++D  kL    RYlq+Y  + +++ + +s+ +s+
  EEA21808.1 107 QTLQEQAKTLQLSLQALAQRIEEVKNDHDKLESENRYLQDYIGSLTQTiS-KSEITST 163
                 77999*************************************99887632.2222222 PP

>> RBD-FIP  FIP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   2.5e-05     0.049      10      28 ..     135     153 ..     127     156 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 2.5e-05
                 HHHHHHHHHHHHHHHHHHH CS
     RBD-FIP  10 qkqEeenrrLedYiDnlLl 28 
                  k E enr+L+dYi +l +
  EEA21808.1 135 DKLESENRYLQDYIGSLTQ 153
                 589***********99865 PP

>> DivIC  Septum formation initiator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   3.7   8.3e-05      0.17      17      58 ..     104     145 ..     100     159 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 8.3e-05
                 XHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC-XXXXXXXX CS
       DivIC  17 laykqlkqeiaalqaelaklkaeneeLeaevkdLksdedyie 58 
                  a++ l+++ ++lq  l++l +++ee +   ++L+s+  y++
  EEA21808.1 104 EARQTLQEQAKTLQLSLQALAQRIEEVKNDHDKLESENRYLQ 145
                 678899999999999999999999999999999988777765 PP

>> JIP_LZII  JNK-interacting protein  leucine zipper II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   3.3   0.00012      0.25       7      67 ..      98     159 ..      95     163 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00012
    JIP_LZII   7 venLikENte.LletknaLnvvkddLIarvdeLtsereiLreEleslqkakerlesrikelE 67 
                 ve L kE  + L+e    L    + L +r++e +++++ L++E++ lq+   +l + i++ E
  EEA21808.1  98 VERLGKEARQtLQEQAKTLQLSLQALAQRIEEVKNDHDKLESENRYLQDYIGSLTQTISKSE 159
                 7777777654388888899999999***********************99999999888766 PP

>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   4.6   0.00016      0.32      14      63 ..      93     141 ..      86     142 .. 0.91
   2 ?    5.9   0.1     0.007        14      30      58 ..     129     157 ..     127     160 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00016
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  14 ReaArrsRqRKqaeieeLerrvkaLekeNksLkseleelkkevekLkskv 63 
                 R +A   R+ K+a++  L++++k+L+   ++L++++ee k++ +kL+s++
  EEA21808.1  93 RDSADVERLGKEARQ-TLQEQAKTLQLSLQALAQRIEEVKNDHDKLESEN 141
                 778888899999997.6*******************************98 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.007
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  30 eLerrvkaLekeNksLkseleelkkevek 58 
                 e ++  ++Le+eN  L++ +++l+ +++k
  EEA21808.1 129 EVKNDHDKLESENRYLQDYIGSLTQTISK 157
                 55666789****************99984 PP

>> DUF5320  Family of unknown function (DUF5320)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   2.1   0.00096       1.9      70      98 ..     101     129 ..      42     130 .. 0.91
   2 ?    0.7   0.0      0.56   1.1e+03      67      90 ..     133     156 ..     129     160 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00096
     DUF5320  70 skeeekelLeeqaeaLeeeleaikkrlke 98 
                   +e ++ L+eqa++L+ +l+a+ +r++e
  EEA21808.1 101 LGKEARQTLQEQAKTLQLSLQALAQRIEE 129
                 5678899********************98 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.56
     DUF5320  67 aeaskeeekelLeeqaeaLeeele 90 
                 ++ + e+e+++L++++ +L + + 
  EEA21808.1 133 DHDKLESENRYLQDYIGSLTQTIS 156
                 556678888888888888887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (173 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1515  (0.0845); expected 358.6 (0.02)
Passed bias filter:                      806  (0.0449551); expected 358.6 (0.02)
Passed Vit filter:                       153  (0.00853366); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.45
# Mc/sec: 1154.53
//
Query:       EEA21809.1  [L=326]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
      0.065   13.9   0.1       0.12   13.1   0.1    1.3  1  NAD_binding_3  Homoserine dehydrogenase, NAD binding domain
      0.082   13.2   0.6       0.15   12.4   0.6    1.4  1  DUF4226        Domain of unknown function (DUF4226)


Domain annotation for each model (and alignments):
>> NAD_binding_3  Homoserine dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.1   1.3e-05      0.12       8      79 ..     149     218 ..     148     219 .. 0.91

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.3e-05
                    HHHHHHHH---SSEEEEEEEEESSEEE-TTHHHHHT--CB---HHHHHHHHS-EEEEE-S--HHHHTTHHHH CS
  NAD_binding_3   8 avleqlkrqqseielelvavadrdsllskdrkallasealtldlddliahldpdvvVEcasseavaelvlka 79 
                    a++++l+++++  + +lv v  ++  +  dr + + ++ ++++l++  ++l p vvVE++ se++++l+ +a
     EEA21809.1 149 ALIKKLAAMKDL-DKQLVKVGGAH-IETVDRTKRADNAYQPQRLPKYRDQLWPTVVVEVGYSESLRKLANDA 218
                    578999999995.99*********.88888999999**********999999**************998775 PP

>> DUF4226  Domain of unknown function (DUF4226)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.6   1.6e-05      0.15       4      47 ..     138     180 ..     135     186 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 1.6e-05
     DUF4226   4 saadAarareaaLaqrlsataelDrqlaevlrsahakaaegrrr 47 
                  +a+A+r+ eaaL+++l+a+ +lD+ql++v  +ah ++++  +r
  EEA21809.1 138 THANASRDFEAALIKKLAAMKDLDKQLVKV-GGAHIETVDRTKR 180
                 689************************986.5666666555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (326 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       600  (0.0334653); expected 358.6 (0.02)
Passed bias filter:                      453  (0.0252663); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 2210.55
//
Query:       EEA21810.1  [L=645]
Description: nucleoporin Nsp1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.6e-39  133.6   0.8      6e-39  132.4   0.8    1.5  1  Nsp1_C           Nsp1-like C-terminal region
    1.3e-05   26.0 142.3      0.014   16.2  22.5    6.9  8  Nucleoporin_FG   Nucleoporin FG repeat region
  ------ inclusion threshold ------
      0.086   13.2   0.7       0.46   10.8   0.0    2.3  2  GAT              GAT domain
       0.15   11.4   3.0       0.26   10.6   3.0    1.3  1  DUF4407          Domain of unknown function (DUF4407)
       0.16   12.3   9.0      0.053   13.9   1.6    2.2  2  OmpH             Outer membrane protein (OmpH-like)
       0.17   11.7   6.4       0.27   11.0   6.4    1.2  1  ERM              Ezrin/radixin/moesin family
       0.31   11.4   8.4        1.6    9.1   4.4    2.1  2  DUF4200          Domain of unknown function (DUF4200)
       0.82   10.2   3.2        5.3    7.6   3.0    2.1  1  DUF16            Protein of unknown function DUF16
        1.3    9.5   2.9        1.8    9.1   0.2    2.3  2  Snapin_Pallidin  Snapin/Pallidin
        1.3    8.8   3.5         25    4.7   1.5    2.3  2  CK2S             Casein Kinase 2 substrate
        1.5    9.2   6.2        1.6    9.1   2.7    2.2  2  Uso1_p115_C      Uso1 / p115 like vesicle tethering protein, 
        1.9    7.8   5.9        3.2    7.0   5.9    1.3  1  GAS              Growth-arrest specific micro-tubule binding
        2.4    7.9   8.4         12    5.6   8.3    1.9  1  TACC_C           Transforming acidic coiled-coil-containing p
        2.4    8.2   5.8         18    5.3   1.3    2.4  2  Laminin_II       Laminin Domain II
        5.8    5.4   7.9        7.4    5.1   2.3    2.0  2  AAA_13           AAA domain
        7.5    7.2   9.7    1.1e+02    3.5   6.5    2.5  2  HIP1_clath_bdg   Clathrin-binding domain of Huntingtin-intera


Domain annotation for each model (and alignments):
>> Nsp1_C  Nsp1-like C-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.4   0.8   5.3e-42     6e-39       3     110 ..     405     513 ..     403     519 .. 0.95

  Alignments for each domain:
  == domain 1  score: 132.4 bits;  conditional E-value: 5.3e-42
      Nsp1_C   3 aktveiapsaas.lknktldelinkWtteLeeqekeFeeqakkvneWDrvLvengekIskLysevleaeqeqnkidqeLeyiesqqdeLeslLdnyEke 100
                 a+t +++p+a+s lknkt+de+i++W+t+L++++keF+eqa+kv+eWDr+Lv n+ k++k+  ++++ae+++++++++L  +e qq+eL+++Ld+yE+e
  EEA21810.1 405 ASTFGPTPPAQSrLKNKTMDEIITRWATDLTKYQKEFKEQAEKVAEWDRMLVVNSGKVQKIFGNTVDAERATQEVERQLASVEGQQEELNAWLDRYERE 503
                 5788899999999************************************************************************************** PP

      Nsp1_C 101 leellskles 110
                 ++e+lsk++ 
  EEA21810.1 504 VDEMLSKQVG 513
                 *****99876 PP

>> Nucleoporin_FG  Nucleoporin FG repeat region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5  41.0      0.24   2.7e+02       4      91 .]       8     114 ..       1     114 [. 0.80
   2 ?    6.0  34.2      0.02        22      21      91 .]      78     161 ..      59     161 .. 0.61
   3 !   15.1  32.9   2.8e-05     0.032       6      91 .]     104     199 ..     102     207 .. 0.85
   4 !   15.8  24.2   1.7e-05     0.019      10      84 ..     179     252 ..     174     258 .. 0.72
   5 !   16.2  22.5   1.3e-05     0.014       1      84 [.     196     285 ..     196     291 .. 0.84
   6 ?    0.6  19.9      0.96   1.1e+03       7      86 ..     250     334 ..     248     339 .. 0.69
   7 ?    4.2  26.8     0.073        81       6      80 ..     292     378 ..     287     388 .. 0.69
   8 ?    1.1  21.6      0.65   7.2e+02       2      81 ..     321     415 ..     320     423 .. 0.44

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.24
  Nucleoporin_FG   4 G..aaatstsgglFGststt.atstgglFGasstatatasggglfgatsqtaasgglFGstnattqtta.........tgglFGstaataqq... 83 
                        +++ ++sgglFGs++ t +t++g+lFG       ++s + lfg+++ ++ +++ FG++++ + + a         tg+ FG+ ++t ++   
      EEA21810.1   8 NppSSTGASSGGLFGSKTPTtTTTGGSLFG---GLGGASSPS-LFGTANPSSGQNNPFGAKTTGAGSGAstpafsfggTGSPFGGLNQTPNNktt 98 
                     3656778899999*9999998889999999...444555555.9999999999999999999887766677889999888889987777766778 PP

  Nucleoporin_FG  84 ........ttsgglFG 91 
                             +t+g+lFG
      EEA21810.1  99 eaaapaqtQTAGSLFG 114
                     9999999888899999 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.02
  Nucleoporin_FG  21 tatstgglFG...........asstatatasggglfgatsqtaasgglFGstnattqttatgglFGstaataqq.....ttsgglFG 91 
                     +   tg+ FG           +++++++t+++g+lfga  +++ +gglFGs++ ++++t ++++F +t a+  +      ++ +lFG
      EEA21810.1  78 SFGGTGSPFGglnqtpnnkttEAAAPAQTQTAGSLFGA--KPSGGGGLFGSNTPAQAKT-GSNMFSTTPANPPPgggttGSAPSLFG 161
                     24555555555544443333233444555555569998..899999****999988876.9999*9999888778876556666888 PP

  == domain 3  score: 15.1 bits;  conditional E-value: 2.8e-05
  Nucleoporin_FG   6 aatstsgglFGststtatstgglFGasstatatasggglfgat........sqtaasgglFGstnattqttatgglFGstaataqq.......tt 85 
                     a+t+t+g+lFG++++    +gglFG s+t++++++g+++f +t         +t ++ +lFG+++a++q   +ggl  ++a+ta++       ++
      EEA21810.1 104 AQTQTAGSLFGAKPSG---GGGLFG-SNTPAQAKTGSNMFSTTpanpppggGTTGSAPSLFGAQPAQKQLP-GGGLTSQAATTATTsptttsqPS 193
                     6899999999999999...999999.777778888888999998888887777788899******999987.99999988888887889999888 PP

  Nucleoporin_FG  86 sgglFG 91 
                     +gglFG
      EEA21810.1 194 AGGLFG 199
                     889999 PP

  == domain 4  score: 15.8 bits;  conditional E-value: 1.7e-05
  Nucleoporin_FG  10 tsgglFGststtatstgglFGasstatatasggglfgatsqtaasgglFGstnattqtta.tgglFGstaataqq..t 84 
                     +++ +   t+t+++s+gglFG    +t++a+ + lfga+ +t+ ++ lF ++++ ++++   ++lFG+++a+ ++  +
      EEA21810.1 179 ATTATTSPTTTSQPSAGGLFG----QTTAATDKPLFGAAPSTTGGSALFSAAKTPATSEGgAKSLFGTATASPTTttQ 252
                     333333344444899******....555555667*****999*********999998877999****99888876423 PP

  == domain 5  score: 16.2 bits;  conditional E-value: 1.3e-05
  Nucleoporin_FG   1 glFGaaatstsgglFGststtatstgglFGasstatatasgg.glfgat.....sqtaasgglFGstnattqttatgglFGstaataqq.t 84 
                     glFG+++++t + lFG++++t t ++ lF a++t+++++ g+ +lfg++     ++t+a+ + F  ++a++ ++a+++ FG++ a+a++ +
      EEA21810.1 196 GLFGQTTAATDKPLFGAAPST-TGGSALFSAAKTPATSEGGAkSLFGTAtasptTTTQAPPSFFKLPTANAGGNASASPFGAPVASASPlQ 285
                     79**999999***********.999*****88888888888889****999997777777888888888888888******9988886663 PP

  == domain 6  score: 0.6 bits;  conditional E-value: 0.96
  Nucleoporin_FG   7 atstsgglFGststt..atstgglFGasstatatasggglfgatsqtaasgglF..Gstnattqtta...tgglFGstaataqqtts 86 
                     +t++  + F  ++++   +++++ FGa  +++++ + +  + a+s+++++++lF  G+t++tt++++     +lF ++ a++++t++
      EEA21810.1 250 TTQAPPSFFKLPTANagGNASASPFGAPVASASPLQPS--TTAASEATPQKSLFnlGGTTSTTPSSTpaaAPSLFAAKPAATTATST 334
                     56666677776666678899999***444444443433..4444788888999988777777766667999*****99999877443 PP

  == domain 7  score: 4.2 bits;  conditional E-value: 0.073
  Nucleoporin_FG   6 aatstsgglF...Gststt....atstgglFGasstatatasggglfgatsqtaasgglFGstnattqtta......tgglFGstaat 80 
                     ++++++++lF   G+tstt    ++++ +lF  +++a++ta+++ +  a+++ta+sgglFG ++a+t++t+      t+   G++++t
      EEA21810.1 292 SEATPQKSLFnlgGTTSTTpsstPAAAPSLFA-AKPAATTATSTPAATAPATTAPSGGLFGVKPAATTATTttatptTTTTTGAATTT 378
                     56778888998855566658888888899***.566666666665666779**********999998887644444333334443333 PP

  == domain 8  score: 1.1 bits;  conditional E-value: 0.65
  Nucleoporin_FG   2 lFG..aaatstsgglFGststtatstgglFG......asstatatasggglfgatsqtaas........gglFGstnattqtta...tgglFGst 77 
                     lF   +aat++++ +  ++++t++++gglFG      +++t+tat+++++ +ga+++taa+            G+++a+    a   +++ FG t
      EEA21810.1 321 LFAakPAATTATSTPAATAPATTAPSGGLFGvkpaatTATTTTATPTTTTTTGAATTTAAAapsvtapiAAPSGAPKAA----ApnlGASTFGPT 411
                     5554433444444444444444688999999876654223333333333344444222222122221112222333333....234477777766 PP

  Nucleoporin_FG  78 aata 81 
                      +++
      EEA21810.1 412 PPAQ 415
                     5555 PP

>> GAT  GAT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.0   0.1         1   1.1e+03      59      73 ..     488     502 ..     455     506 .. 0.58
   2 ?   10.8   0.0   0.00041      0.46       9      73 ..     506     579 ..     502     581 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.0 bits;  conditional E-value: 1
         GAT  59 qlNDeLnnvlerYer 73 
                    +eLn  l rYer
  EEA21810.1 488 GQQEELNAWLDRYER 502
                 345889999999988 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00041
         GAT   9 emLsst.........epd.eellenellkeLyetckamqpriqklieetadeedllaelLqlNDeLnnvlerYer 73 
                 emLs+          + d e      l ++L e++ +m + +  +iee+++ +++l +  ++ + ++ +++ +er
  EEA21810.1 506 EMLSKQvgpgealqgP-DqERERTYKLAEKLSERLDEMGKDLGSMIEEINNASSTLSKTNKTDEPVSPTMLSHER 579
                 7888877777766542.446788899***********************999999*9999999999999999987 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   3.0   0.00023      0.26     110     217 ..     428     565 ..     423     589 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00023
     DUF4407 110 aelaeeqqeeakelkeqlaaa.......................ltaelaeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaa 185
                 ++ a+   + +ke+keq ++                        ++  ++e e+q+a+ +++ ++++a ld+ ++e+++ l+ + g g ++ +G  ++ 
  EEA21810.1 428 TRWATDLTKYQKEFKEQAEKVaewdrmlvvnsgkvqkifgntvdAERATQEVERQLASVEGQQEELNAWLDRYEREVDEMLSKQVGPG-EALQGPDQER 525
                 5555555556666666665556668888888999999999999999999999999999999999999999999999999999999999.5699999999 PP

     DUF4407 186 kekkaqldaaqaelaelkakld........atarlaalra 217
                 ++  + +++++++l+e+ ++l         a+++l++ ++
  EEA21810.1 526 ERTYKLAEKLSERLDEMGKDLGsmieeinnASSTLSKTNK 565
                 9999999999999999999955544444444444444444 PP

>> OmpH  Outer membrane protein (OmpH-like)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.9      0.13   1.4e+02      21      49 ..     420     448 ..     414     458 .. 0.80
   2 ?   13.9   1.6   4.7e-05     0.053       7     113 ..     462     568 ..     453     587 .. 0.71

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.13
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        OmpH  21 qeqlekkfkklqaeleakekelqklqeel 49 
                 ++ +++ +++++++l++ +ke+++++e+ 
  EEA21810.1 420 NKTMDEIITRWATDLTKYQKEFKEQAEKV 448
                 45677777999999999999999998886 PP

  == domain 2  score: 13.9 bits;  conditional E-value: 4.7e-05
                 HHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTS..-HHHHHH.HHHHHHHHHHHHHHHHHHHHHHHHHHHH...HHHHHHHH CS
        OmpH   7 vqkileespegkaaqeqlekkfkklqaeleakekelqklqeelqkkakkl.ekeekeqe.lqkkeqelqqkqqqkaqelqkkqqellk...pildkink 100
                 vqki+ ++ ++++a +++e++     a +e +++el++  ++++++  ++ +k+    e lq   qe ++   + a++l ++  e+ k   +++++in+
  EEA21810.1 462 VQKIFGNTVDAERATQEVERQL----ASVEGQQEELNAWLDRYEREVDEMlSKQVGPGEaLQGPDQERER-TYKLAEKLSERLDEMGKdlgSMIEEINN 555
                 799*************998888....55555556666666666666666655444444468888888888.55666888888877666555799***** PP

                 HHHHHHHHTT-SE CS
        OmpH 101 aikevakekgydl 113
                 a + + k+++ d 
  EEA21810.1 556 ASSTLSKTNKTDE 568
                 *****99999875 PP

>> ERM  Ezrin/radixin/moesin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   6.4   0.00024      0.27      20     163 ..     433     589 ..     417     610 .. 0.63

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00024
         ERM  20 eaekaqeaLreseetaelLaekarraeeeaelLeqkaaeaeeeiqrlkesaekeeeekeklerklreaeleaarle..............eeserkeee 104
                 +  k q++ +e+ e++ + ++ + +   + ++   +  +ae+++q+++++ +  e ++e+l++ l+++e+e+ ++               +e+er  + 
  EEA21810.1 433 DLTKYQKEFKEQAEKVAEWDRMLVVNSGKVQKIFGNTVDAERATQEVERQLASVEGQQEELNAWLDRYEREVDEMLskqvgpgealqgpdQERERTYKL 531
                 455555555555555555555555555555555556666666666666666666666666666666666666666666666666666666********* PP

         ERM 105 aerLkeeleeareaeeeakekllealstpskseseenveeseteeeeenseeesaelet 163
                 ae+L e+l e+ +++  + e++ +a+st sk+++++++ +++  ++e  +++  ++l++
  EEA21810.1 532 AEKLSERLDEMGKDLGSMIEEINNASSTLSKTNKTDEPVSPTMLSHE-RRNTDLTDLSN 589
                 ***************************99766443333333332222.22222344444 PP

>> DUF4200  Domain of unknown function (DUF4200)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   4.4    0.0014       1.6      23     106 ..     421     507 ..     414     509 .. 0.87
   2 ?    4.1   0.1     0.053        59      54     101 ..     518     565 ..     515     571 .. 0.88

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0014
     DUF4200  23 qrleealkqreeelekkeqeleedllkf...dkflkendakraralkkaeeerklkkekeaeikklkaeietlkseiekleekleey 106
                 +++ e +++   +l k ++e++e+++k+   d++l  n  k ++   ++ + +++++e e++++  + + e+l++ ++++e++++e+
  EEA21810.1 421 KTMDEIITRWATDLTKYQKEFKEQAEKVaewDRMLVVNSGKVQKIFGNTVDAERATQEVERQLASVEGQQEELNAWLDRYEREVDEM 507
                 556677777778899999999998876544499***************************************************986 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.053
     DUF4200  54 lkendakraralkkaeeerklkkekeaeikklkaeietlkseieklee 101
                 l+  d++r+r  k ae+ +++ +e+ +++  + +ei++  s ++k+ +
  EEA21810.1 518 LQGPDQERERTYKLAEKLSERLDEMGKDLGSMIEEINNASSTLSKTNK 565
                 6677999*****************************999999998876 PP

>> DUF16  Protein of unknown function DUF16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   3.0    0.0047       5.3      32     102 ..     472     542 ..     415     551 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0047
                 BHHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHHHHHHHHH.......HHHHHHHHHHHHHHHHHHH CS
       DUF16  32 nkqrLkkieakvdklgeqinkleqkvekqgekikelkveqkaqgeelnkvdetleliletLqkinkRlDsi 102
                  +   +++e ++++ + q+++l+   ++ + +++e+  +q   ge+l+  d+  e   +  +k+++RlD++
  EEA21810.1 472 AERATQEVERQLASVEGQQEELNAWLDRYEREVDEMLSKQVGPGEALQGPDQERERTYKLAEKLSERLDEM 542
                 55566889999999999*******************************88888888888888888888887 PP

>> Snapin_Pallidin  Snapin/Pallidin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.2    0.0016       1.8      15      50 ..     476     511 ..     472     518 .. 0.90
   2 ?   -0.4   0.0       1.4   1.6e+03      19      50 ..     536     567 ..     527     580 .. 0.57

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0016
  Snapin_Pallidin  15 ldeldeklkelrqsQeeLleqldrlnekLkeleeaq 50 
                       +e++ +l++++ +QeeL++ ldr  ++++e+   q
       EEA21810.1 476 TQEVERQLASVEGQQEELNAWLDRYEREVDEMLSKQ 511
                      6899**************************998766 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 1.4
  Snapin_Pallidin  19 deklkelrqsQeeLleqldrlnekLkeleeaq 50 
                       e+l e  +    + e++++ ++ L ++++++
       EEA21810.1 536 SERLDEMGKDLGSMIEEINNASSTLSKTNKTD 567
                      34444444444455555555555555555555 PP

>> CK2S  Casein Kinase 2 substrate
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   1.5     0.022        25       1      62 [.     436     495 ..     436     511 .. 0.85
   2 ?    3.7   0.0     0.047        52      59      92 ..     530     563 ..     518     576 .. 0.88

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.022
        CK2S   1 klrkafrkveeqrekWkellsesesllesl.snlaeqlqalqnvklygtplrdfpdlqerLre 62 
                 k++k f++  e+ + W+++l   +  +++  +n ++  +a+q+v+++   l++++++qe+L +
  EEA21810.1 436 KYQKEFKEQAEKVAEWDRMLVVNSGKVQKIfGNTVDAERATQEVERQ---LASVEGQQEELNA 495
                 799*****************999999987549*************88...9999999999864 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.047
        CK2S  59 rLrekqlealeevlakLrekleelqkvrdslekl 92 
                 +L ek+ e l+e+ ++L +++ee++++ ++l+k 
  EEA21810.1 530 KLAEKLSERLDEMGKDLGSMIEEINNASSTLSKT 563
                 688999999********************99986 PP

>> Uso1_p115_C  Uso1 / p115 like vesicle tethering protein, C terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.1      0.51   5.8e+02      44      87 ..     417     456 ..     412     459 .. 0.69
   2 ?    9.1   2.7    0.0014       1.6       2      67 ..     475     545 ..     474     587 .. 0.73

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.51
  Uso1_p115_C  44 esqakeleaenkklekeleklraelkeekekekekqkEldDLLl 87 
                  + ++k++++ + +   +l k ++e ke++ek     +E d +L+
   EEA21810.1 417 RLKNKTMDEIITRWATDLTKYQKEFKEQAEKV----AEWDRMLV 456
                  55677777777777778888888888866665....56666665 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.0014
  Uso1_p115_C   2 kaseleseaaslkdeneklkaelqslskalesleqk.....eakkaaesqakeleaenkklekeleklrae 67 
                  +++e+e++ as++ ++e+l+a l+  ++++ ++ +k     ea++ ++++ +++ + ++kl+++l+++ + 
   EEA21810.1 475 ATQEVERQLASVEGQQEELNAWLDRYEREVDEMLSKqvgpgEALQGPDQERERTYKLAEKLSERLDEMGKD 545
                  579*********************************88888666666666666666666666655444433 PP

>> GAS  Growth-arrest specific micro-tubule binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   5.9    0.0029       3.2      44     184 ..     422     565 ..     414     574 .. 0.73

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0029
         GAS  44 rnekelseisqenkrlkepLkkaeeeveeLrkqlk....nyekdkqslknlkarlkelekelkdlkwehevleqrfekvekerdelykkfeaaiqevqq 138
                  ++  +   +++  +++++ k++ e+v+e  + l     + +k +     +++  +e+e++l +++ ++e l+  +++ e+e de+ +k+    +   q
  EEA21810.1 422 TMDEIITRWATDLTKYQKEFKEQAEKVAEWDRMLVvnsgKVQKIFGNTVDAERATQEVERQLASVEGQQEELNAWLDRYEREVDEMLSKQVGPGEA-LQ 519
                 4444555555666667777777777777766654321115666666677789999**********************************9985544.44 PP

         GAS 139 ktglknllLekklkalqeelEkkeaqleevlaaanldpaalsavse 184
                   + +     k  ++l+e+l++  + l +++++ n   ++ls+ ++
  EEA21810.1 520 GPDQERERTYKLAEKLSERLDEMGKDLGSMIEEINNASSTLSKTNK 565
                 4555555555667889999999999999999999988888887765 PP

>> TACC_C  Transforming acidic coiled-coil-containing protein (TACC), C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   8.3     0.011        12       5     128 ..     422     541 ..     418     575 .. 0.50

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.011
      TACC_C   5 dldaalekvkeeveekeeeiqelkkkveelkkenqemkkivaefektiaqlieekqkqkelakkeiqkvleekeqlladlnsveksfsdlfkryekqke 103
                  +d+ +++   + ++ ++e   +k++ e+  +e  +m ++ +   + i   + ++++ +++ +++++ v  ++e+l+a l   e+++++++++     e
  EEA21810.1 422 TMDEIITRWATDLTKYQKE---FKEQAEKV-AEWDRMLVVNSGKVQKIFGNTVDAERATQEVERQLASVEGQQEELNAWLDRYEREVDEMLSKQVGPGE 516
                 5555555555555554444...33332222.22333444444444444444445555555566666666666666666666666666666665555555 PP

      TACC_C 104 vlegykkneeslkkcaeeylarvkk 128
                 +l+g  +  e+  k ae++ +r+ +
  EEA21810.1 517 ALQGPDQERERTYKLAEKLSERLDE 541
                 5555555555555555544444433 PP

>> Laminin_II  Laminin Domain II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   1.3     0.016        18       9      81 ..     424     496 ..     416     513 .. 0.68
   2 ?    4.7   0.2     0.026        29      12      76 ..     532     596 ..     523     604 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.016
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--TTTTTGGGHHHHHHH CS
  Laminin_II   9 netakevleqlaplsqnlentkeklseinrsveetnekvkdankairdArrsvkkLeklapqLldklkelkql 81 
                 +e+++    +l++ +++ ++  ek+ e +r +     kv++    ++dA+r+ +++e+++  ++ + +el+  
  EEA21810.1 424 DEIITRWATDLTKYQKEFKEQAEKVAEWDRMLVVNSGKVQKIFGNTVDAERATQEVERQLASVEGQQEELNAW 496
                 5555666666777777777777777777777777777778888888888888888888887777777777654 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.026
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--TTTTTGGGHH CS
  Laminin_II  12 akevleqlaplsqnlentkeklseinrsveetnekvkdankairdArrsvkkLeklapqLldklk 76 
                 a++  e l ++ ++l  + e+++++ +++ +tn+  +  + ++ + +r   +L+ l ++   kl 
  EEA21810.1 532 AEKLSERLDEMGKDLGSMIEEINNASSTLSKTNKTDEPVSPTMLSHERRNTDLTDLSNRPNPKLT 596
                 56777889999999999999999999999999999999988888888888888887776655555 PP

>> AAA_13  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   2.6     0.013        15     393     471 ..     416     501 ..     413     519 .. 0.71
   2 ?    5.1   2.3    0.0066       7.4      98     207 ..     483     601 ..     476     611 .. 0.54

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.013
      AAA_13 393 eeakkklelhlveeleseldeykkkykklekaieklekelkeeeaelkkleee.......ikeLekqlrdekpaaeeinkeLkafG 471
                 +++k+k    ++ +   +l++y+k++k+ ++++ + ++ l  ++ +++k+ ++        +e e+ql +++   ee+n  L ++ 
  EEA21810.1 416 SRLKNKTMDEIITRWATDLTKYQKEFKEQAEKVAEWDRMLVVNSGKVQKIFGNtvdaeraTQEVERQLASVEGQQEELNAWLDRYE 501
                 56777777777778888888888888888888888888887777777777655555555577777777777777777777777773 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0066
      AAA_13  98 ieklkkeikkleekleaaeaqlqkaek.........ekkklekeledeawkkivkkknsalsealkglkyeekfkerllk.elkkknrkaaellsdeel 186
                 +++ +++ ++l++ l+  e+++++  +         +  + e e ++++++k+ ++   ++ ++l ++ +e ++++  l+ + k+++    ++ls e++
  EEA21810.1 483 LASVEGQQEELNAWLDRYEREVDEMLSkqvgpgealQGPDQERERTYKLAEKL-SERLDEMGKDLGSMIEEINNASSTLSkTNKTDEPVSPTMLSHERR 580
                 55555555555444444444443333334445554433344455555666655.344444445555555555555555552455556667777788888 PP

      AAA_13 187 kakletvesenlpelaplsls 207
                 + +l+ +++++ p+l++l +s
  EEA21810.1 581 NTDLTDLSNRPNPKLTSLPTS 601
                 888888888888887777554 PP

>> HIP1_clath_bdg  Clathrin-binding domain of Huntingtin-interacting protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   3.2      0.37   4.1e+02      25      95 ..     434     503 ..     419     507 .. 0.56
   2 ?    3.5   6.5       0.1   1.1e+02      41      89 ..     525     574 ..     469     582 .. 0.71

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.37
  HIP1_clath_bdg  25 verekkeleeelerlkeeaerkleeqkeelekLkreleakraelarlkssLesseqsgeqlssqlaaLqaE 95 
                     + + +ke +e+ e++ e  +r+l   + +++k+  +  + +   ++++  L+s e ++e+l++ l+  ++E
      EEA21810.1 434 LTKYQKEFKEQAEKVAE-WDRMLVVNSGKVQKIFGNTVDAERATQEVERQLASVEGQQEELNAWLDRYERE 503
                     55555555555555433.33344444555555555555555555555556666666666665555555555 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.1
  HIP1_clath_bdg  41 eeaerkleeq.keelekLkreleakraelarlkssLesseqsgeqlssql 89 
                     +e++ kl+e+ +e l+++ ++l +  +e++++ s+L+++++++e +s ++
      EEA21810.1 525 RERTYKLAEKlSERLDEMGKDLGSMIEEINNASSTLSKTNKTDEPVSPTM 574
                     34444555552677999999999999999999999999999999888766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (645 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1347  (0.0751297); expected 358.6 (0.02)
Passed bias filter:                      749  (0.0417759); expected 358.6 (0.02)
Passed Vit filter:                       113  (0.00630264); expected 17.9 (0.001)
Passed Fwd filter:                        26  (0.00145016); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              16  [number of targets reported over threshold]
# CPU time: 1.00u 0.36s 00:00:01.36 Elapsed: 00:00:00.54
# Mc/sec: 3599.99
//
Query:       EEA21811.1  [L=522]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
   5.1e-110  368.1   1.2   5.1e-110  368.1   1.2    1.6  2  DUF5102      Domain of unknown function (DUF5102)


Domain annotation for each model (and alignments):
>> DUF5102  Domain of unknown function (DUF5102)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.2      0.28     5e+03      17     208 ..      34      56 ..      15      72 .. 0.45
   2 !  368.1   1.2  2.8e-114  5.1e-110       1     289 []     232     522 .]     232     522 .] 0.89

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 0.28
     DUF5102  17 dddFgDFddgfqeeeaeeseeaeeeepaepsasslsfplldfesldlesdllaaleeeldelfppseekeirslevplskesqiflterslsLwsqLva 115
                 +d F D  +g  e++                                                                                    
  EEA21811.1  34 EDHFSDASEGQPESR------------------------------------------------------------------------------------ 48 
                 222333322211111.................................................................................... PP

     DUF5102 116 pPplqppnWirSriRRlfLvsLGvPvdLDeiLpaskqkklvLPsleleseksssssrssrvkrlkqanasstsvdssasakksrssssrrrgp 208
                                                                                                      s+++ r+ 
  EEA21811.1  49 -------------------------------------------------------------------------------------SRKSSRAA 56 
                 .....................................................................................11111222 PP

  == domain 2  score: 368.1 bits;  conditional E-value: 2.8e-114
     DUF5102   1 fgdDfddFeegaeaeddddFgDFddgfqeeeaees.eeaeeeepa.epsasslsfplldfesldlesdllaaleeeldelfppseekeirslev..pls 95 
                 fgd+fddFeega+a  dddFgDFd+gf e+++ +  +e+ e+e+  +p+++   +plldf+ + + sdll++++++ld+lfp++++  ++sl++  p++
  EEA21811.1 232 FGDEFDDFEEGANATVDDDFGDFDEGFGEPAEGAVgDESGESEILqQPTTPLPLPPLLDFTLTASLSDLLSTTNNSLDTLFPETKT--VPSLPSldPIP 328
                 79************99*************99555555665555554899999999***************************9997..555553359** PP

     DUF5102  96 kesqiflterslsLwsqLvapPplqppnWirSriRRlfLvsLGvPvdLDeiLpaskqkklvLPsleleseksssssrssrvkrlkq......anassts 188
                 ++++if++erslsLwsqLvapPplqppnW++SriRRlfLvsLGvPvdLDeiLpaskqkkl+LPs++ e +++s +++  +v+++kq      +n+s+ts
  EEA21811.1 329 DSTAIFSSERSLSLWSQLVAPPPLQPPNWVKSRIRRLFLVSLGVPVDLDEILPASKQKKLILPSINPEDSSTSVRTK--AVSKAKQgdatspQNDSTTS 425
                 *****************************************************************997654444444..34444443345678999999 PP

     DUF5102 189 vdssasakksrssssrrrgpppePelDlkaarrLcattdeaLkgltdeeLkehvkeLeelteeasevLeYwlkrrDekigdkEafegvIenLVkharkv 287
                 v+s+ s++ks    srrrg+p +PelDl a+rrLcattd+aL+g+td+eL++hv +L++ +++a++vL+Yw kr+D++ig+kEafegvIenLV+har+ 
  EEA21811.1 426 VNSTISRQKS----SRRRGQPAPPELDLFAVRRLCATTDAALDGFTDSELEQHVVTLKTASTKAQDVLDYWVKRTDGLIGEKEAFEGVIENLVNHARRA 520
                 9999988766....799*********************************************************************************9 PP

     DUF5102 288 rk 289
                 rk
  EEA21811.1 521 RK 522
                 97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (522 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       669  (0.0373138); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.31s 00:00:00.89 Elapsed: 00:00:00.47
# Mc/sec: 3327.81
//
Query:       EEA21812.1  [L=294]
Description: phytanoyl-CoA dioxygenase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-15   56.9   0.0    4.4e-15   56.5   0.0    1.1  1  PhyH      Phytanoyl-CoA dioxygenase (PhyH)


Domain annotation for each model (and alignments):
>> PhyH  Phytanoyl-CoA dioxygenase (PhyH)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.5   0.0   2.4e-19   4.4e-15       2     210 ..      38     236 ..      37     237 .. 0.76

  Alignments for each domain:
  == domain 1  score: 56.5 bits;  conditional E-value: 2.4e-19
                 HHHSEEEETTSS-HHHHHHHHHHHHHHHHHCHTTCCSEEEEECEEESTTCCCEE.CCCHHCHHHHTTHHHHHHHHHHHHTSCEEEEEEEEEEEEE...E CS
        PhyH   2 eedGylviegflsaeevealraeiealldralesgdkidfffeekaaadedgll.eksinkvghflhprkvadlvrailgqdvyvaavlqsmyqd...i 96 
                 + dG +v+ ++++ + +++l+a++   + r l++++  + +f  ++ + + +++ ++   +++++++    +++v++ lg++ +      ++y +    
  EEA21812.1  38 HNDGIVVLNNAIDTTHLDKLNARMVP-EARTLYNKSTTHRNFGPSTGNIQQEPVlQEGYIFYDVIANT-FATQVVECMLGPNLAL-----RFY-SantA 128
                 78**********************98.45555555544444444444444444449***********9.5555555555555542.....455.22323 PP

                 EE-TTTCB-EEEEE-SGGGST.EESGCCEEEEEEESS-B-TTBT-EEEETTGGGS-CCGTCCHHCSGCCTTSCCCTTTGHGSCEEEE.BTTTEEEEEET CS
        PhyH  97 fkqpkiGgevqpwHqDstflp.tdpeesvvgvwialedateenGclrfiPGSHkweegplrrrlpeddteaeddeakkedeeeavpvevkaGdavlfhg 194
                 fk+   G   qp+H D +f + +   +   +v i l d ++ nG++ + PG+H+   +      + +++ +++  +++++ ++ v+  + +G++++ + 
  EEA21812.1 129 FKAT--GR--QPPHIDVHFDFpCG-VPFGYCVNINLVDTSPLNGATEVWPGTHLGTSIN--DMSDTEPGIRKELVEERRKIRPPVQPSLPKGSLIIRDF 220
                 3333..44..8********88444.689999************************7773..44444555555889999********************* PP

                 TSEEEE-TB.SSSXEE CS
        PhyH 195 rllHgsgaNrsdksRr 210
                 rl+H++++N++d +R 
  EEA21812.1 221 RLWHAGRPNQTDEPRV 236
                 *************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (294 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       348  (0.0194099); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.48
# Mc/sec: 1832.61
//
Query:       EEA21813.1  [L=1095]
Description: MIZ zinc finger domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-09   36.5   0.2    8.1e-09   35.1   0.2    1.8  1  zf-MIZ    MIZ/SP-RING zinc finger
      2e-05   24.3   0.4    4.4e-05   23.2   0.4    1.6  1  zf-Nse    Zinc-finger of the MIZ type in Nse subunit


Domain annotation for each model (and alignments):
>> zf-MIZ  MIZ/SP-RING zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.1   0.2   9.1e-13   8.1e-09       2      49 ..     951    1005 ..     950    1006 .. 0.86

  Alignments for each domain:
  == domain 1  score: 35.1 bits;  conditional E-value: 9.1e-13
                  ESB-TTTSSB-SSEEEETT--SS--EEHHHHHHHHHHS--.......-B-TTT-- CS
      zf-MIZ    2 slkCplslsrikiPvrgekCkHlqCfdlesylelnertet.......WnCPvCsk 49  
                  +l+ p++++  +iPvr++ C+H  Cfdl+++l++ + +          +CP+C k
  EEA21813.1  951 DLRDPFTTRIFEIPVRSSLCTHRECFDLSTFLQTLAAKAMgekhtiyVRCPICRK 1005
                  6777999999***********************987766666677779*****87 PP

>> zf-Nse  Zinc-finger of the MIZ type in Nse subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.2   0.4   4.9e-09   4.4e-05       1      56 [.     939    1003 ..     939    1004 .. 0.89

  Alignments for each domain:
  == domain 1  score: 23.2 bits;  conditional E-value: 4.9e-09
                  SXXXXXS..SBXXSB-TTTSSB-SSEEEESSS--..EEEHHHHHHHC.......TTTS-EE-SCCC- CS
      zf-Nse    1 delaiee..erislkCPltlqpfeePvtskkCpH..vFEreaIleli.......krkktvkCPvagC 56  
                  del+i      i+l++P t + fe Pv+s  C H   F+ ++ l+ +       k++  v+CP+  C
  EEA21813.1  939 DELMIMDdfISIDLRDPFTTRIFEIPVRSSLCTHreCFDLSTFLQTLaakamgeKHTIYVRCPI--C 1003
                  78888884457899********************666***************99999999***9..7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1095 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       830  (0.0462937); expected 358.6 (0.02)
Passed bias filter:                      345  (0.0192426); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.88u 0.34s 00:00:01.22 Elapsed: 00:00:00.49
# Mc/sec: 6693.72
//
Query:       EEA21814.1  [L=1001]
Description: polarized growth protein (Boi2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.8e-11   44.4   0.0    5.7e-11   42.9   0.0    1.8  1  PH        PH domain
    1.1e-10   41.2   0.1    2.3e-10   40.2   0.1    1.6  1  SH3_9     Variant SH3 domain
    1.4e-09   37.4   0.0    3.2e-09   36.3   0.0    1.6  1  SH3_1     SH3 domain
      3e-09   36.9   0.2    5.1e-09   36.1   0.2    1.4  1  SAM_2     SAM domain (Sterile alpha motif)
    0.00024   20.7   0.1    0.00052   19.6   0.1    1.5  1  SH3_2     Variant SH3 domain
  ------ inclusion threshold ------
      0.012   16.1   0.0      0.028   14.8   0.0    1.6  1  PH_11     Pleckstrin homology domain
      0.038   14.4   0.1      0.076   13.5   0.1    1.5  1  SAM_1     SAM domain (Sterile alpha motif)
      0.046   14.0   0.0       0.15   12.3   0.0    1.8  2  PH_8      Pleckstrin homology domain


Domain annotation for each model (and alignments):
>> PH  PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.9   0.0   2.5e-14   5.7e-11       2     103 ..     744     887 ..     743     888 .. 0.92

  Alignments for each domain:
  == domain 1  score: 42.9 bits;  conditional E-value: 2.5e-14
                 EEEEEEEEETSSSSCSEEEEEEEEETTEEEEESSTTCTTESSEEEEEESTTEEEEEEEC.....................................TTS CS
          PH   2 vkeGwLlkkgsgkkkswkkrwfvLkdsellyykndksekdkepkgsislsncevvevva.....................................ted 63 
                 +++Gw++k++ +  ++wk r fvL++ +l+yy ++    d e +g i+++ ++v + ++                                     +++
  EEA21814.1 744 EYSGWMKKRSANLMTTWKPRLFVLRGRRLSYYYSE---NDTEERGLIDITAHRVLRADNdpltalhatitgakssptspegstkspmdkafdaagsPKS 839
                 689*******************************9...9*****************999************************************777* PP

                 SSSTSEEEE........EESTSSSTEEEEEEESSHHHHHHHHHHHHHH CS
          PH  64 pkrkfcfel........riverngsrtyllqasseeerkeWikaiqsa 103
                 ++ +f f+l        r+v+ ++++ +++q++s  e + W++a+ +a
  EEA21814.1 840 SDGPFIFKLvppksgasRTVQFTRPTIHYFQVDSVKEGRLWMAALMKA 887
                 *********8887777766655557*******************9876 PP

>> SH3_9  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.2   0.1     1e-13   2.3e-10       1      49 []      18      71 ..      18      71 .. 0.89

  Alignments for each domain:
  == domain 1  score: 40.2 bits;  conditional E-value: 1e-13
       SH3_9  1 AlypyepreddeLsLqrGDvitvieese...dgWlegsl..tGrtGlvPanyve 49
                +++++++r +deL L+rG+ + + e +e   dgW++g+   tG+tGl+P  y++
  EEA21814.1 18 VIHNFDARGEDELTLRRGEKVELVELDEgfgDGWYLGKHtaTGKTGLFPGVYTT 71
                79*********************96655566*******448***********85 PP

>> SH3_1  SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.3   0.0   1.4e-12   3.2e-09       2      47 ..      18      66 ..      17      67 .. 0.96

  Alignments for each domain:
  == domain 1  score: 36.3 bits;  conditional E-value: 1.4e-12
                ESSSBEXSSTTBXEBSTTEEEEEEEECSS...SEEEEEETTSTEEEEEE CS
       SH3_1  2 AlYDYeaeesdELsfkkGDviivleksed...gWwkgrlkgtgkeGliP 47
                ++++++a+ +dEL++++G++++++e +e+   gW+ g+ + tgk+Gl+P
  EEA21814.1 18 VIHNFDARGEDELTLRRGEKVELVELDEGfgdGWYLGKHTATGKTGLFP 66
                5889*********************9999******************** PP

>> SAM_2  SAM domain (Sterile alpha motif)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.1   0.2   2.3e-12   5.1e-09       2      66 .]     254     320 ..     253     320 .. 0.95

  Alignments for each domain:
  == domain 1  score: 36.1 bits;  conditional E-value: 2.3e-12
                 GGHHHHHHHHHHHHTTT.GGGHHHHHHTTCSHHHHHTTSCHHHH..HHTTHHHHHHHHHHHHHHHHHH CS
       SAM_2   2 eswsledvaeWLrsigl.kqytdnFrdagitgaelllrlteedL..krlGitsvghrkkilkkiqelk 66 
                   w++ +++++L  +g   +++d+F +++itg ++ll++ +e+L  k+++   +g+r+k+++ki++l+
  EEA21814.1 254 RRWDHIETSRYLHGLGVdSRHCDIFQEQEITG-DVLLEMGQEFLlmKEFDFGVMGRRLKTWHKIKALQ 320
                 5799999*************************.***********977******************996 PP

>> SH3_2  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.1   2.3e-07   0.00052       4      50 ..      18      66 ..      16      69 .. 0.89

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 2.3e-07
                ESS-B-SCGCCB--B-TTEEEEEE..EEEECTTEEEEEE..CCCEEEEE CS
       SH3_2  4 aiedyvgedkseLsfkkGdvikvlslgskdsdgwwegev..gGrvGlfP 50
                +i ++++  ++eL++++G+ + +++l +   dgw++g     G+ GlfP
  EEA21814.1 18 VIHNFDARGEDELTLRRGEKVELVELDEGFGDGWYLGKHtaTGKTGLFP 66
                6889********************77777777*****66599******9 PP

>> PH_11  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.8   0.0   1.2e-05     0.028       3      36 ..     747     782 ..     745     830 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 1.2e-05
       PH_11   3 Gylkkkgsk...aWkrrwfavlkdgvLeyYksekkkv 36 
                 G++kk+++    +Wk r f vl+ ++L+yY se++  
  EEA21814.1 747 GWMKKRSANlmtTWKPRLF-VLRGRRLSYYYSENDTE 782
                 888888888999*******.************99865 PP

>> SAM_1  SAM domain (Sterile alpha motif)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.1   3.4e-05     0.076       3      42 ..     256     296 ..     254     316 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 3.4e-05
                 TTHSSHHHHHHHTTS.GGGHHHHHTTTSSHHHHTTSCHHHH CS
       SAM_1   3 wsvedVgeWLesigl.gqYadlFrageidgdaLlllteddL 42 
                 w++ + ++ L+ +g  ++++d F+++ei+gd Ll++ ++ L
  EEA21814.1 256 WDHIETSRYLHGLGVdSRHCDIFQEQEITGDVLLEMGQEFL 296
                 7777888899999999********************99985 PP

>> PH_8  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   6.9e-05      0.15       1      51 [.     747     796 ..     747     805 .. 0.87
   2 ?   -2.5   0.0       2.8   6.4e+03      23      35 ..     861     873 ..     858     888 .. 0.55

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 6.9e-05
        PH_8   1 gillkkrrkklqgyakRfFvLdlksstlsYyrddnssalrgkiplsla.iis 51 
                 g++ k+    +  ++ R FvL  +   lsYy+++n+++ rg i ++   ++ 
  EEA21814.1 747 GWMKKRSANLMTTWKPRLFVL--RGRRLSYYYSENDTEERGLIDITAHrVLR 796
                 799999999999*********..999****************9998764555 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 2.8
        PH_8  23 lksstlsYyrddn 35 
                 +++ t++Y++ d 
  EEA21814.1 861 FTRPTIHYFQVDS 873
                 5566666666543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1001 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       462  (0.0257683); expected 358.6 (0.02)
Passed bias filter:                      297  (0.0165653); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.70u 0.26s 00:00:00.96 Elapsed: 00:00:00.45
# Mc/sec: 6643.95
//
Query:       EEA21815.1  [L=580]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    0.00039   21.0   3.2     0.0011   19.5   3.2    2.0  1  Metallophos  Calcineurin-like phosphoesterase


Domain annotation for each model (and alignments):
>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   3.2   6.4e-08    0.0011      15     173 ..     160     365 ..      87     438 .. 0.64

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 6.4e-08
                  CTHHHHHHHHHHHHHHHTTESEEEEESTSSSSS..........................................HHHHHHHHHHHHHHHH.TSEEEE CS
  Metallophos  15 ggqlddllkllddllreekpdlvllaGDlvdrg..........................................dlekellellaalvky.pipvyl 69 
                   g+ ++l+ +++ l r ++p  v ++GDl+                                             + e e+l+ ++    +  ++++ 
   EEA21815.1 160 LGNDYYLAHIYRTLSRWSRPTHVTVLGDLIGSQwvtdeefenrgwrfwnrvfrggqrvdddiratggkphgegsqQEELEILQRYNS---SwANRIIN 254
                  38999999999999888899999999**55555555555666668888888888899999999999999887544222222222333...255799** PP

                  EC-TTS....CHHHHHHHHHHHHHHH.HHHHEHHHCEEETSEEEEEETTE.......EEEEEEESECEEETHHHHHHHHHHHSCHHHHCC......HH CS
  Metallophos  70 llGNHe....gfeeellnkygylgif.sepwrsdaevfnnlplaslgsgs.......lkvlllhGgspellvsldklgslnleleapepg......de 149
                  ++GNH+    g + +  ++++++  f +++w   +  f ++pl +  +         l+ l+l+G        ld+  +                 ++
   EEA21815.1 255 VAGNHDigyaG-DVSEARLERFERVFgPANW---DVRFAHPPLEDESDARptlhiinLNDLTLDGP------PLDPSIQ----------SdsytyvND 332
                  ******87642.2244444444444467777...67788999988333333333333477777776......2222223..........133333344 PP

                  HHHH..HHHHTTCSEEEEEESSESS.......C CS
  Metallophos 150 wlkd..lekrekadwvivlgHsply.......r 173
                  +l +  +  ++++ ++++l+H+pl+       +
   EEA21815.1 333 LLTHrsYPVEDQTSFTLLLTHVPLHkrdgicvD 365
                  44446788899**************75444330 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (580 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       439  (0.0244855); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.25s 00:00:00.85 Elapsed: 00:00:00.42
# Mc/sec: 4136.53
//
Query:       EEA21816.1  [L=921]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (921 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       767  (0.0427799); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.67u 0.28s 00:00:00.95 Elapsed: 00:00:00.44
# Mc/sec: 6236.85
//
Query:       EEA21817.1  [L=557]
Description: diphthamide biosynthesis protein Dph2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.2e-87  294.2   0.0      3e-87  292.9   0.0    1.6  1  Diphthamide_syn  Putative diphthamide synthesis protein


Domain annotation for each model (and alignments):
>> Diphthamide_syn  Putative diphthamide synthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  292.9   0.0   1.7e-91     3e-87       1     302 [.      61     415 ..      61     416 .. 0.90

  Alignments for each domain:
  == domain 1  score: 292.9 bits;  conditional E-value: 1.7e-91
  Diphthamide_syn   1 fPegllpdsaeiadil.eef.......gae.....................................vvilgDttYGaCcvdevaaehlgadll 49 
                      fP+++lpd++++++ l + +       +                                       ++il+Dt+YG Ccvdevaaeh++ad++
       EEA21817.1  61 FPDDMLPDAPRVFQLLtRGLqtknaksD-IepavaettnadpettltektsqlgledsksldelerrFYILADTSYGTCCVDEVAAEHVDADAV 153
                      8999999999999999655566655441.05666667777788888888888888899999999999*************************** PP

  Diphthamide_syn  50 vHyGhsclspvdrlpvlYvfveieldvehlvetlkknfke.kkkivlvstiqyahaleevkeeleeegyevvkvpqsekplspgevlgctspkl 142
                      vHyG++clsp++rlpv+Yvf++++l +e lv+++k+++++ + ki+++++++y+++++ev++ l + gy+++  + +  +++++ + ++t p+ 
       EEA21817.1 154 VHYGRACLSPTSRLPVIYVFTHRPLPIEPLVKAFKNTYTDlTAKIIIAADVTYTDHVQEVHDRLVQGGYTNL-FAAEVVHNPASAIPNRTVPES 246
                      **************************************555999*********************99*****.66666999***********99 PP

  Diphthamide_syn 143 keeeeevd.....ailyigdgrfhllslmlsn.pklpvyrydpys..kklteesydakkllrrRyaaiekakdakkvGiivgtlgvqgrlelve 228
                       e  e++d     ++++i+d++++ll ++ s+  ++++y  + ++  ++++  + ++  +lrrRy ++ ++ +a  +Gi+v+tl+v+++l++v+
       EEA21817.1 247 VE--ENADtlsewELFHISDPPTALLLTLSSRvAAIHIYPTENVEseEEIKPLQASTTAALRRRYGVLVSLSTAPIFGILVNTLSVKNYLHIVD 338
                      74..46665566677****************97788999554444246899999**************************************** PP

  Diphthamide_syn 229 rlkkllkeagkksylvlvgelnpakLanfaeidafVlvaCprlsiddgkeFekPvltpyElevalg...erewteey 302
                      +++k++++agkksy+++vg+ln ak+anf+ei+++V+++C+++s++d+k+F+kPv+tpyEle+al+   +r wt+ +
       EEA21817.1 339 HVRKQIAAAGKKSYMFVVGKLNAAKVANFSEIEGWVVIGCWESSLVDSKDFWKPVITPYELELALQsddTRVWTGAW 415
                      ******************************************************************99999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (557 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       328  (0.0182944); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.43
# Mc/sec: 3872.90
//
Query:       EEA21818.1  [L=357]
Description: maleylacetate reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-79  268.0   0.2    1.2e-79  267.8   0.2    1.0  1  Fe-ADH    Iron-containing alcohol dehydrogenase
    1.5e-15   57.6   0.1      2e-15   57.2   0.1    1.1  1  Fe-ADH_2  Iron-containing alcohol dehydrogenase
  ------ inclusion threshold ------
      0.081   13.6   0.0        0.3   11.8   0.0    2.1  1  IMS_C     impB/mucB/samB family C-terminal domain


Domain annotation for each model (and alignments):
>> Fe-ADH  Iron-containing alcohol dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  267.8   0.2     2e-83   1.2e-79       1     362 [.      10     338 ..      10     340 .. 0.97

  Alignments for each domain:
  == domain 1  score: 267.8 bits;  conditional E-value: 2e-83
                 -SEEEEETTGGGGHHHHHTTT-..EEEEEEEHHHH.HH.THHHHHHHHHCTT-EEEE.EEE-S---HHHHHHHHTTS-TT.--EEEEEESHHHHHHHHH CS
      Fe-ADH   1 PtrivfgkgaleelgellkklgakralivtdkgslkksglldkvlesleeagievtvfdgvepnptleeveeaaalareegadvviavGGGsviDtAKa 99 
                 P r+vfg+g+l++l+e++++l+++ +l++ +++ +   + +++++e l  +g    +f++ + + +++  e+a++ a+e++ad+v+++GGGs+i ++Ka
  EEA21818.1  10 PGRVVFGSGTLKQLPEEVSRLNLTAPLLLSTPQQI---SQAEQLKEIL--NGKIAGIFTEATMHTPTDITEKALQYAKETKADAVVSIGGGSTIGLGKA 103
                 89*******************************88...789*******..5555569****************************************** PP

                 HHHHTT..................--EEEEESS-S-S-TT-SEEEEE.-TTSEEEEE-..SS--SEEEEEHHHHHHS-HHHHHHHHHHHHHHHHHHHHH CS
      Fe-ADH 100 ialllanpevedylgegkakkkkalpliaiPTtaGtGsevtplavitdeeegeklsifdpellPdlaivDpeltltlPkrvtaatglDalahalEayvs 198
                 i++ ++                  lp+i+iPTt   Gse+tp+   t  ++g+k++ +dp++lP ++i+D +lt+tlP+++ a++g++a+aha+Ea+ +
  EEA21818.1 104 ISIRTG------------------LPHICIPTTY-AGSEMTPILGET--ADGVKKTRSDPKILPGTVIYDVDLTMTLPAAMSATSGVNAIAHAVEALYA 181
                 ******..................**********.9********999..778*********************************************** PP

                 HT---TTSSB--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSS---HHHHHHHHHHC.CGGGGGS-HHHHHHHHH..........HHHHH CS
      Fe-ADH 199 kkanplsdalaleairliaknleravadgedleareqmllastlaglafsnaglgavHalahalgalfgiphglanaillpavlrfnaeaaperlaqla 297
                 +++np+ + lale+ + +a +l+++v++++++ ar+q l++++l g +++++g++++H l h+lg+ f++ph +++  +lp+++ +na++ pe +++la
  EEA21818.1 182 RNTNPIINLLALEGTKALASSLPEIVENPSSPSARSQALYGAWLCGTCLGSVGMSIHHKLCHTLGGSFNLPHAETHTAVLPHAISYNAPRIPEAMKKLA 280
                 *************************************************************************************************** PP

                 HT.......T--HHHHHHHHHHHHHTT---SHHHHT-TT-HHHHHHHHHT-TSGGGGSSS---HH CS
      Fe-ADH 298 ralggesdeeaaeeliealrellkelglptsLselgvdeedldklaeaalkdrslannpreltae 362
                 +al      e+  ++i  l  ll++l+++++L+++g++eed+dk a+ a+++   + npre+++e
  EEA21818.1 281 EAL-----PESNGDAIHGLNVLLSKLKVKRGLKDFGMKEEDIDKAADIAVSN--PYWNPREIERE 338
                 **7.....689999***********************************766..9999**99987 PP

>> Fe-ADH_2  Iron-containing alcohol dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.2   0.1   3.3e-19     2e-15       2     239 ..      15     249 ..      14     260 .. 0.84

  Alignments for each domain:
  == domain 1  score: 57.2 bits;  conditional E-value: 3.3e-19
    Fe-ADH_2   2 igegaleklgellkelelkkvllvadentkkaagekveeslkeagikvevveeveeeadleeveklvealreketdlvvavGgGtiiDiakyvsaklnv 100
                 +g+g+l++l+e +++l+l+  ll++  +  +  +e+++e l+ +     +++e++ +   +  ek ++ ++e+++d+vv++GgG+ i ++k +s ++++
  EEA21818.1  15 FGSGTLKQLPEEVSRLNLTAPLLLSTPQQIS-QAEQLKEILNGKI-AG-IFTEATMHTPTDITEKALQYAKETKADAVVSIGGGSTIGLGKAISIRTGL 110
                 7899*************99887777665444.45899****9994.33.5677777888888899999999**************************** PP

    Fe-ADH_2 101 pyvsvpTaaSvDGfaspgaslvvdgkkrtv.akaaaPlaviaDldvlaeAPrrllasGvGDllgkytaladwklanevseplaklsaamvqeaaeklve 198
                 p + +pT+ +    +      + dg k+t   +  +P  vi D+d+  + P+++ a    ++++  +     + +n + + la++  + + +++ ++ve
  EEA21818.1 111 PHICIPTTYAGSEMTPILGE-TADGVKKTRsDPKILPGTVIYDVDLTMTLPAAMSATSGVNAIAHAVEALYARNTNPIINLLALEGTKALASSLPEIVE 208
                 ********987666544433.45677777769999*******************97555578888888888899999999******************* PP

    Fe-ADH_2 199 dkketealeellealalsgigisrpaSGsEHliSHaldmla 239
                 ++ + +a +++l +  l+g+   + +    H++ H l   +
  EEA21818.1 209 NPSSPSARSQALYGAWLCGTCLGSVGMSIHHKLCHTLGGSF 249
                 *********************998888889*****997765 PP

>> IMS_C  impB/mucB/samB family C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   5.1e-05       0.3      59     108 ..     252     302 ..     148     308 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 5.1e-05
       IMS_C  59 dfhasrsatLprpt.sdtreileaalkLlrrlidepglpirligvsasnlv 108
                 +  ++++a Lp++  +++  i ea++kL ++l   +g+ i  ++v +s+l 
  EEA21818.1 252 PHAETHTAVLPHAIsYNAPRIPEAMKKLAEALPESNGDAIHGLNVLLSKLK 302
                 3349********555**************999888**************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (357 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       442  (0.0246528); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 2485.37
//
Query:       EEA21819.1  [L=432]
Description: nucleolar protein Jip5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    7.9e-10   38.9   0.0     0.0013   19.0   0.0    3.1  2  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
    2.1e-06   28.3   4.4      0.072   14.0   0.5    5.0  6  WD40         WD domain, G-beta repeat


Domain annotation for each model (and alignments):
>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.0   0.0   1.5e-07    0.0013      27      80 ..      79     130 ..      24     139 .. 0.87
   2 !   16.2   0.0   1.1e-06    0.0096      28      91 ..     283     350 ..     276     351 .. 0.80

  Alignments for each domain:
  == domain 1  score: 19.0 bits;  conditional E-value: 1.5e-07
  ANAPC4_WD40  27 qrvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvks 80 
                    +w++    ++++ r+La++ dg+ L  a  dg v+  ++e+g vv+++ + +
   EEA21819.1  79 DTIWST--RRHKGSCRCLAFSTDGETLYSAGTDGIVKAAKVETGIVVNKILIPQ 130
                  568888..89999**********************************9986544 PP

  == domain 2  score: 16.2 bits;  conditional E-value: 1.1e-06
  ANAPC4_WD40  28 rvwtleedkedsevrsLaWkpd....gklLavaysdgevrlldaesgkvvhslsvksekavtclgWge 91 
                  r++ + +++e++  +sLa  p+    gk+ av+ sdg+++l+ +   kv++ ++ ++ + vt+lg+ +
   EEA21819.1 283 RIYVARQNGEGEALESLAVVPSdagyGKMVAVGQSDGQISLVAIGRNKVLSRVQHDEVEGVTSLGFDV 350
                  566666666666666776655433339************************************99875 PP

>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       1.2     1e+04      15      33 ..      20      38 ..      13      40 .. 0.68
   2 !   14.0   0.5     8e-06     0.072       6      35 ..      83     113 ..      71     113 .. 0.82
   3 ?   -3.1   0.0         2   1.8e+04      16      38 .]     151     169 ..     145     169 .. 0.59
   4 ?    1.6   0.0     0.067     6e+02       3      28 ..     181     216 ..     179     226 .. 0.67
   5 ?   -1.2   0.0      0.52   4.6e+03      21      35 ..     308     322 ..     298     323 .. 0.83
   6 !    9.4   0.0   0.00023       2.1       9      38 .]     336     366 ..     328     366 .. 0.80

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 1.2
                EEEEETTSSEEEEE.ETTSE CS
        WD40 15 slafspdgawlasG.sdDgt 33
                ++a++p+ + l+ G +  g+
  EEA21819.1 20 AQAVHPSEPILSVGlT-SGH 38
                5678888888766632.444 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 8e-06
                 EEESS.SSEEEEEEETTSSEEEEEETTSEEE CS
        WD40   6 tltGH.ssvtslafspdgawlasGsdDgtvr 35 
                 + + H +s ++lafs dg  l s++ Dg v+
  EEA21819.1  83 STRRHkGSCRCLAFSTDGETLYSAGTDGIVK 113
                 4556866699***********98888**997 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 2
                 EEEETTSSEEEEEETTSEEEEEE CS
        WD40  16 lafspdgawlasGsdDgtvriWd 38 
                 l  sp + +la+ +  g ++++d
  EEA21819.1 151 L--SPQNLLLAT-D-SGALHVYD 169
                 4..666666643.4.66666665 PP

  == domain 4  score: 1.6 bits;  conditional E-value: 0.067
                 EEEEEESS.SSEEEEE.........EETTSSEEEEE CS
        WD40   3 clrtltGH.ssvtsla.........fspdgawlasG 28 
                 + +t++ H + ++sl             +++w+++G
  EEA21819.1 181 PEQTYRPHdDYISSLTalppsdtstSGYSKQWVTTG 216
                 567899995449888865555555555555556655 PP

  == domain 5  score: -1.2 bits;  conditional E-value: 0.52
                 TSSEEEEE.ETTSEEE CS
        WD40  21 dgawlasG.sdDgtvr 35 
                 +g+++a G s Dg + 
  EEA21819.1 308 YGKMVAVGqS-DGQIS 322
                 6788999988.*9986 PP

  == domain 6  score: 9.4 bits;  conditional E-value: 0.00023
                 SSSS...EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   9 GHss...vtslafspdgawlasGsdDgtvriWd 38 
                  H+    vtsl f+ +g+++ sG+  + +++W+
  EEA21819.1 336 QHDEvegVTSLGFDVEGRMV-SGG-GQVIKVWS 366
                 573344599999*******7.8**.*******5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (432 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       557  (0.031067); expected 358.6 (0.02)
Passed bias filter:                      359  (0.0200234); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.41
# Mc/sec: 3181.55
//
Query:       EEA21820.1  [L=160]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (160 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       842  (0.046963); expected 358.6 (0.02)
Passed bias filter:                      588  (0.032796); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 1150.23
//
Query:       EEA21821.1  [L=704]
Description: hypothetical protein PMAA_056130 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.6e-05   21.2   1.1    0.00016   19.9   1.1    1.7  1  Sporozoite_P67  Sporozoite P67 surface antigen


Domain annotation for each model (and alignments):
>> Sporozoite_P67  Sporozoite P67 surface antigen
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   1.1   9.2e-09   0.00016     114     327 ..     303     676 ..     298     691 .. 0.54

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 9.2e-09
  Sporozoite_P67 114 edseedddeeeeednkstssk....dgkgskkaqpgvssssgsttsqtdlstk....lsqtglgasGshaqqdpavsvsgv............vg 188
                      d+++d d+++++dn   s+     +g + + + p+ ++  g +  ++ + +k       tg g+ Gs++  dp  + +g              g
      EEA21821.1 303 ADDDDD-DDDDDDDNYHLSAPhpgiGGEDQHGSYPAADPHPGASGPGQGTYAKpgpySGPTGPGNDGSYSATDPHAGAPGPeghgsypaadpyPG 396
                     333333.334455555555431111445555558888888888877776665522225679999****************999999**9999999 PP

  Sporozoite_P67 189 vpGlgvpGvGvpGvggvgvlpgvgvprvgvapgvGvg..........glggv............pgvgv.......................... 235
                     +pGlg +    p  gg+g  p       +  pg G            glggv            pg+g                           
      EEA21821.1 397 APGLGQGTYAAPSPGGIGSYPAADPYPGASGPGQGTYakpgpysgptGLGGVgsypaadphpgaPGLGQgtyakpgpysgptgpgddasypaadp 491
                     ************99999999988766666667766656777777444555555555555554443333355555554444444444444444444 PP

  Sporozoite_P67 236 .......................................lesnssseGeedddeeeeeenksie............................... 260
                                                                                                                    
      EEA21821.1 492 hpgapypgpagpgddgsysapdpypgasgpgqgtyakpgP-----------------------Ysgptgpgddagypapdphyaaggdkqehgsy 563
                     4444444444444333343333333333333333444440.......................04444444444444444444444444444444 PP

  Sporozoite_P67 261 .............................................pgvGvpGvrvgaatssssttspssstttttpassgpsaqgshgsss.rna 309
                                                                  p v  p v+  +++s    +s   s++   +  s+ s      +s   ++
      EEA21821.1 564 sdpalggyqsspqtyhkpspgqpeleydpskpslpshqygkpaaqPFVPHPVVTAYHSSSVRIQSSHLPSSSHHASHGSSHSHVAHTTTSCqWTS 658
                     45555555555566666666666666666666666666666666666666654444444444333333333333333333333333333330345 PP

  Sporozoite_P67 310 vtrstdsisgpipspGep 327
                     ++r+t+  s   ps   p
      EEA21821.1 659 TARKTEGPSLTAPSAMSP 676
                     556666655555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (704 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       409  (0.0228122); expected 358.6 (0.02)
Passed bias filter:                      185  (0.0103185); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.64u 0.31s 00:00:00.95 Elapsed: 00:00:00.49
# Mc/sec: 4321.38
//
Query:       EEA21822.1  [L=398]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.17   11.9   0.1       0.31   11.2   0.1    1.3  1  CRF       Corticotropin-releasing factor family


Domain annotation for each model (and alignments):
>> CRF  Corticotropin-releasing factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.1   1.7e-05      0.31       8      24 ..     100     119 ..      98     122 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 1.7e-05
                 HHHHHHH...HHHHHHHHHH CS
         CRF   8 pfhvLRq...lleiARaksq 24 
                  +h+LR+   ll++AR+k++
  EEA21822.1 100 ATHILRSawgLLQNARNKMM 119
                 69****************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (398 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       350  (0.0195214); expected 358.6 (0.02)
Passed bias filter:                      270  (0.0150594); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.23s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2827.53
//
Query:       EEA21823.1  [L=367]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (367 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       341  (0.0190195); expected 358.6 (0.02)
Passed bias filter:                      265  (0.0147805); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 2604.05
//
Query:       EEA21824.1  [L=266]
Description: GAJ protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    7.7e-22   77.4   0.9      2e-21   76.1   0.0    2.1  2  Mnd1         Mnd1 HTH domain
     0.0019   17.6   4.6     0.0026   17.2   4.6    1.2  1  Dynamitin    Dynamitin
     0.0021   15.7   8.2      0.003   15.2   8.2    1.1  1  DUF3584      Protein of unknown function (DUF3584)
  ------ inclusion threshold ------
      0.024   14.9   0.0       0.24   11.7   0.0    2.3  2  DsrD         Dissimilatory sulfite reductase D (DsrD)
      0.066   12.6   1.6      0.096   12.0   1.6    1.2  1  DUF4407      Domain of unknown function (DUF4407)
       0.14   12.3  11.3       0.29   11.3  11.3    1.5  1  End3         Actin cytoskeleton-regulatory complex protein EN
        0.2   11.1  13.8       0.29   10.6  13.8    1.1  1  HMMR_N       Hyaluronan mediated motility receptor N-terminal
       0.23   11.8   7.8       0.74   10.1   0.2    2.7  3  BLOC1_2      Biogenesis of lysosome-related organelles comple
        1.2    9.2   4.3          5    7.2   0.5    2.7  3  DASH_Dad4    DASH complex subunit Dad4
        2.5    8.9   7.2         25    5.6   6.7    2.6  2  DUF2203      Uncharacterized conserved protein (DUF2203)
          8    6.8  13.1         15    6.0  13.1    1.4  1  OmpH         Outer membrane protein (OmpH-like)


Domain annotation for each model (and alignments):
>> Mnd1  Mnd1 HTH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.1   0.0   1.2e-24     2e-21       1      60 []      58     117 ..      58     117 .. 0.98
   2 ?   -1.5   0.2         2   3.3e+03       5      28 ..     189     212 ..     186     215 .. 0.81

  Alignments for each domain:
  == domain 1  score: 76.1 bits;  conditional E-value: 1.2e-24
        Mnd1   1 ileifqeskefytlKeleklapkekgivsqsVkdvlqsLvdDglveveKiGssnvyWsFp 60 
                 il++++++ +++tlK+lek++p+ ++i+  +Vkd ++ L++++++++eKiGs n+yWsFp
  EEA21824.1  58 ILDHIRSTCTCHTLKDLEKMLPSVASINGIQVKDFITGLLNENKICMEKIGSNNWYWSFP 117
                 7999*******************************************************8 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 2
        Mnd1   5 fqeskefytlKeleklapkekgiv 28 
                 +q++k+ ++ + + k+ +k   i+
  EEA21824.1 189 LQTQKTAFEDNGVSKIKQKTEEIN 212
                 788899999999999999988887 PP

>> Dynamitin  Dynamitin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   4.6   1.6e-06    0.0026      84     178 ..     122     217 ..     104     245 .. 0.77

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 1.6e-06
   Dynamitin  84 adegeeketleqklqRLqrEveeleeEvekakeaakeseeeeldpvelaeqleslqkqLeel.eellgedsaa.sltdaqealakrllsqleefkes 178
                  ++++ +e l + l+RL   ve+le+Ev+k+++ ake ee   dp+++  +  sl +q +el  e+ + ++++ +++d+  +++k+ ++++++ k++
  EEA21824.1 122 RERKNVQERLLRDLNRLTKTVEQLEDEVQKKQARAKE-EEGTRDPMDIEIERRSLMEQKAELfIEIEQLQTQKtAFEDNGVSKIKQKTEEINNWKRE 217
                 2223366777777*****************9999987.888889**999999999999999985665556666677777778888888877777655 PP

>> DUF3584  Protein of unknown function (DUF3584)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   8.2   1.9e-06     0.003     272     371 ..     125     229 ..     117     247 .. 0.66

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1.9e-06
     DUF3584 272 kadeerlaekqeevqeakaelkqqlrtledelkeaideln.qelsaakaklaakes....elealeeqkkkyedadieklkadldqlpsirseleelee 365
                 k+ +erl + +++  ++ ++l+ +++++++  ke++ ++   +++ ++  l ++++    e+e+l+ qk ++ed++++k k++ +++ ++++e+   e 
  EEA21824.1 125 KNVQERLLRDLNRLTKTVEQLEDEVQKKQARAKEEEGTRDpMDIEIERRSLMEQKAelfiEIEQLQTQKTAFEDNGVSKIKQKTEEINNWKREIDIWED 223
                 44444445555555555555555555555555554444332344444455544444233378*******************************998888 PP

     DUF3584 366 eldalt 371
                 ++  ++
  EEA21824.1 224 NISIME 229
                 777665 PP

>> DsrD  Dissimilatory sulfite reductase D (DsrD)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00015      0.24       3      49 ..      56     103 ..      53     113 .. 0.79
   2 ?    0.5   0.0      0.45   7.4e+02      24      44 ..     113     133 ..     104     136 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00015
                 HHHHHHHSSCCCSS-EEHHHHHHH-TTS-H...HHHHHHHHHHHHTTSEE CS
        DsrD   3 kaiveflekkkkKskfYfkDlekalPdakp...reiKkvvneLVnegkLe 49 
                 k+i++ +++    + + +kDlek+lP++ +    ++K +++ L ne+k+ 
  EEA21824.1  56 KMILDHIRSTC--TCHTLKDLEKMLPSVASingIQVKDFITGLLNENKIC 103
                 67788888777..8899*******99875422279***********9975 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.45
                 HHH-TTS-HHHHHHHHHHHHH CS
        DsrD  24 ekalPdakpreiKkvvneLVn 44 
                 +  +P+  +re K+v  +L +
  EEA21824.1 113 YWSFPSDEKRERKNVQERLLR 133
                 456999********9998876 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   1.6   5.9e-05     0.096     133     248 ..     126     247 ..      90     253 .. 0.66

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 5.9e-05
     DUF4407 133 aelaeleaqiaalqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaakekkaqldaaqaelaelkakld............atarlaalrael 219
                 + +++l +++++l ++++++e+++++++a a++e +     gt   +  + + ++  +q +++  e+++l+++ +            +t+++++ ++e+
  EEA21824.1 126 NVQERLLRDLNRLTKTVEQLEDEVQKKQARAKEE-E-----GTRDPMDIEIERRSLMEQKAELFIEIEQLQTQKTafedngvskikqKTEEINNWKREI 218
                 3344555555566666666666666666666533.3.....3444556666667777777777777777777755777777777777777888888888 PP

     DUF4407 220 aeleaerakeraasqaaaaaddGllarle 248
                 +  e++++  ++   + a +d+Gl + ++
  EEA21824.1 219 DIWEDNISIMEQYLYKLAGGDRGLVEAIK 247
                 77777777777777777777777776665 PP

>> End3  Actin cytoskeleton-regulatory complex protein END3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3  11.3   0.00018      0.29      94     196 ..     123     233 ..      98     236 .. 0.50

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00018
        End3  94 gtdweevrLkreLaeLeeklekveeeaekr..kekereessksalvkreleqLLkYKeeqlreleegegkske......knlksvkedietveeqVegL 184
                 + ++ + rL r+L+ L + +e++e+e++k+  + ke+e + +++ +  e   L++ K e   e e+ ++++++      +++k+ +e+i++ +  +++ 
  EEA21824.1 123 ERKNVQERLLRDLNRLTKTVEQLEDEVQKKqaRAKEEEGTRDPMDIEIERRSLMEQKAELFIEIEQLQTQKTAfedngvSKIKQKTEEINNWKREIDIW 221
                 333335678888888888888888777777433445555555666666666777777654333333222222111001133444445555555555555 PP

        End3 185 esylssrkeeLe 196
                 e+ +s  ++ L 
  EEA21824.1 222 EDNISIMEQYLY 233
                 555555444444 PP

>> HMMR_N  Hyaluronan mediated motility receptor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6  13.8   0.00018      0.29     217     327 ..     119     231 ..     115     236 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00018
      HMMR_N 217 kekieekseteklleyieelsnvseql..ekykldiaqleellkekndeiesLkssLeekeqelskqvkdlnekckllekekeelvreeeekeqtlsaE 313
                 +ek e k  +e+ll   ++l ++ eql  e  k++ ++ ee       +ie+ + sL e++ el  ++++l+++    e +   +++++ e  ++ + E
  EEA21824.1 119 DEKRERKNVQERLLRDLNRLTKTVEQLedEVQKKQARAKEEEGTRDPMDIEIERRSLMEQKAELFIEIEQLQTQKTAFEDNGVSKIKQKTEEINNWKRE 217
                 7899999999*****************63345555555666666666899999****************************9999******9******* PP

      HMMR_N 314 leelkeklklkeqe 327
                 ++  ++++   eq 
  EEA21824.1 218 IDIWEDNISIMEQY 231
                 **999999998885 PP

>> BLOC1_2  Biogenesis of lysosome-related organelles complex-1 subunit 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.9     0.021        34      54      83 ..     122     151 ..     117     160 .. 0.79
   2 ?   -1.3   0.0       1.7   2.8e+03      57      79 ..     176     198 ..     170     201 .. 0.71
   3 ?   10.1   0.2   0.00046      0.74      49      84 ..     200     235 ..     191     238 .. 0.91

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.021
     BLOC1_2  54 nekyeelqpylqqidqiekqvteLeeavse 83 
                 +e+++  + +l+ ++++ k+v++Le+ v++
  EEA21824.1 122 RERKNVQERLLRDLNRLTKTVEQLEDEVQK 151
                 555666677899999999999999998886 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.7
     BLOC1_2  57 yeelqpylqqidqiekqvteLee 79 
                  e+ ++++ +i+q+++q t +e+
  EEA21824.1 176 MEQKAELFIEIEQLQTQKTAFED 198
                 55666777788888888777775 PP

  == domain 3  score: 10.1 bits;  conditional E-value: 0.00046
     BLOC1_2  49 kleklnekyeelqpylqqidqiekqvteLeeavseL 84 
                  ++k+++k ee+++ +++id  e++++ +e+  ++L
  EEA21824.1 200 GVSKIKQKTEEINNWKREIDIWEDNISIMEQYLYKL 235
                 57899**************************99998 PP

>> DASH_Dad4  DASH complex subunit Dad4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0         3   4.9e+03       4      16 ..      50      62 ..      50      85 .. 0.67
   2 ?    7.2   0.5     0.003         5       8      42 ..     123     157 ..     118     164 .. 0.83
   3 ?    2.4   0.1     0.095   1.5e+02      19      49 ..     200     230 ..     198     236 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 3
   DASH_Dad4  4 PheeqqsalLsRI 16
                P e +q+++L+ I
  EEA21824.1 50 PPEVKQKMILDHI 62
                5577788888766 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.003
   DASH_Dad4   8 qqsalLsRIiknvekLnesvvelnkeleeinkkNk 42 
                 + +++ +R+++ +++L+++v++l+ e+++ +++ k
  EEA21824.1 123 ERKNVQERLLRDLNRLTKTVEQLEDEVQKKQARAK 157
                 567888999**************999998777665 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.095
   DASH_Dad4  19 nvekLnesvvelnkeleeinkkNknvelvsq 49 
                  v+k+ ++ +e+n+  +ei     n++++ q
  EEA21824.1 200 GVSKIKQKTEEINNWKREIDIWEDNISIMEQ 230
                 5889999999999999999988888888887 PP

>> DUF2203  Uncharacterized conserved protein (DUF2203)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0       1.6   2.6e+03      72      84 ..      85      97 ..      60     105 .. 0.76
   2 ?    5.6   6.7     0.015        25      10      75 ..     130     192 ..     125     243 .. 0.67

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 1.6
     DUF2203 72 lGvevkdleaglv 84
                 G++vkd+  gl+
  EEA21824.1 85 NGIQVKDFITGLL 97
                4888888877776 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.015
     DUF2203  10 alLpllkelleelralrkeleeleeeleeakaeaekse....aaeleaeleeleaeieelveeieelGve 75 
                 +lL  l++l++ + +l++e+++++++ +e+       e     +  e e ++l+++  el+ eie+l  +
  EEA21824.1 130 RLLRDLNRLTKTVEQLEDEVQKKQARAKEE-------EgtrdPMDIEIERRSLMEQKAELFIEIEQLQTQ 192
                 455555555555555555555555444444.......344445555555555555555555566555444 PP

>> OmpH  Outer membrane protein (OmpH-like)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0  13.1     0.009        15      16     105 ..     123     211 ..     119     231 .. 0.66

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.009
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTS.-HHHHHHHHHHHHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHHHHH CS
        OmpH  16 egkaaqeqlekkfkklqaeleakekelqklqeelqkkakklekeekeqelqkkeqelqqkqqqka...qelqkkqqellkpildkinkaikev 105
                 e+k++qe+l ++ ++l +++e++e+e+qk+q++ ++++ +    ++  +++ +++ l++++++ +   ++lq ++ ++ ++ + ki++ ++e+
  EEA21824.1 123 ERKNVQERLLRDLNRLTKTVEQLEDEVQKKQARAKEEEGT----RDPMDIEIERRSLMEQKAELFieiEQLQTQKTAFEDNGVSKIKQKTEEI 211
                 6788999999999999999999999999999999733333....2333355566666663333335555555555555555555555555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (266 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2221  (0.123878); expected 358.6 (0.02)
Passed bias filter:                      845  (0.0471303); expected 358.6 (0.02)
Passed Vit filter:                        87  (0.00485247); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.64u 0.33s 00:00:00.97 Elapsed: 00:00:00.50
# Mc/sec: 1598.24
//
Query:       EEA21825.1  [L=252]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
       0.16   12.2   0.0       0.25   11.6   0.0    1.3  1  UAF_Rrn10  UAF complex subunit Rrn10


Domain annotation for each model (and alignments):
>> UAF_Rrn10  UAF complex subunit Rrn10
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   1.4e-05      0.25      65     110 ..     105     153 ..      88     160 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 1.4e-05
   UAF_Rrn10  65 dldlrvvqdyatelllakyk....kliealdesslltlGllvekwvkdyl 110
                 d+ l++vq ya ++  +++     + + +++ s+l+++G+l+e+  +++l
  EEA21825.1 105 DI-LEAVQSYAGHFYANTGDnrrtEHFSSMNGSALIAMGILLEELGNELL 153
                 67.899********999885222257999**************9877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (252 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       716  (0.0399353); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 1854.98
//
Query:       EEA21826.1  [L=480]
Description: WD repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    5.3e-19   68.2  13.7    0.00027   21.7   0.4    6.4  6  WD40         WD domain, G-beta repeat
    1.7e-07   31.4   0.5       0.29   11.5   0.0    4.9  4  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   5.8e-07    0.0052       9      38 .]      61      92 ..      51      92 .. 0.76
   2 !    8.5   0.1   0.00042       3.8       9      36 ..     118     149 ..     113     149 .. 0.85
   3 !    4.6   0.1    0.0072        65       5      36 ..     161     195 ..     157     197 .. 0.70
   4 !   14.2   0.0   6.9e-06     0.062       4      38 .]     204     240 ..     201     240 .. 0.83
   5 !   21.7   0.4     3e-08   0.00027       4      38 .]     278     313 ..     276     313 .. 0.91
   6 !    6.0   0.0    0.0027        24      13      37 ..     409     438 ..     398     439 .. 0.76

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 5.8e-07
                SS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS
        WD40  9 GH.ssvtsla.fspdgawlasGsdDgtvriWd 38
                +H ++v+ la    +g++l+sG+ D+++r+Wd
  EEA21826.1 61 AHkGGVNVLAiDRNYGRYLVSGGADPSIRLWD 92
                675456656556677888*************9 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00042
                 SS.SSEEEEE...EETTSSEEEEEETTSEEEE CS
        WD40   9 GH.ssvtsla...fspdgawlasGsdDgtvri 36 
                 +H  s ts++   f+p  + +++ s+D+t+++
  EEA21826.1 118 AHtHSLTSISiypFDPTPSTILTTSRDNTLKL 149
                 553369999999**********99******97 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.0072
                 EEEESS.SS.EEEEEEETTSSEE.EEEETTSEEEE CS
        WD40   5 rtltGH.ss.vtslafspdgawl.asGsdDgtvri 36 
                 +t+  H ++  +sl+ ++ +++l a+G+  +t+r+
  EEA21826.1 161 HTFNLHaTPyCHSLSSHSASTLLiAAGTSERTIRL 195
                 66666765577888877777776257755****98 PP

  == domain 4  score: 14.2 bits;  conditional E-value: 6.9e-06
                 EEEEESS.SSEEEEEEETTSSEEE.EEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgawla.sGsdDgtvriWd 38 
                 ++tl GH s v sl + p+ ++++ s+s D+   i+d
  EEA21826.1 204 THTLLGHdSAVLSLEWAPHRPYILaSASTDNRAIIFD 240
                 69999**777************752668899887776 PP

  == domain 5  score: 21.7 bits;  conditional E-value: 3e-08
                 EEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   4 lrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 
                 +r+ ++H++  t++++ ++g+ l++++ D  +r+Wd
  EEA21826.1 278 TRHGRAHNGaLTGVRWTSNGSHLITAGQDSRLRVWD 313
                 57889**5559************************9 PP

  == domain 6  score: 6.0 bits;  conditional E-value: 0.0027
                 EEEEEEETTSSE.....EEEEETTSEEEEE CS
        WD40  13 vtslafspdgaw.....lasGsdDgtvriW 37 
                 +++la+  +g       l+s++ Dgt+r W
  EEA21826.1 409 INGLAWRGNGGSgegleLFSAHGDGTIRTW 438
                 89996555555577777999*88*****99 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.0      0.12   1.1e+03      47      68 ..      73      94 ..      53     104 .. 0.79
   2 !    9.1   0.0   0.00018       1.6      52      90 ..     183     220 ..     172     222 .. 0.87
   3 !   11.5   0.0   3.2e-05      0.29      33      71 ..     280     318 ..     271     327 .. 0.86
   4 ?    2.4   0.0     0.022   1.9e+02      37      63 ..     405     436 ..     390     441 .. 0.69

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 0.12
  ANAPC4_WD40 47 kpdgklLavaysdgevrlldae 68
                 ++ g+ L+ + +d ++rl d  
   EEA21826.1 73 RNYGRYLVSGGADPSIRLWDLD 94
                 5679**************9975 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.00018
  ANAPC4_WD40  52 lLavaysdgevrlldaesgkvvhslsvksekavtclgWg 90 
                  l+a ++s+ ++rlld  sg   h+l  +++ av +l+W+
   EEA21826.1 183 LIAAGTSERTIRLLDLRSGLATHTLLGHDS-AVLSLEWA 220
                  7899********************966666.7******7 PP

  == domain 3  score: 11.5 bits;  conditional E-value: 3.2e-05
  ANAPC4_WD40  33 eedkedsevrsLaWkpdgklLavaysdgevrlldaesgk 71 
                  +  ++++  ++++W  +g+ L  a +d+++r+ da +g 
   EEA21826.1 280 HGRAHNGALTGVRWTSNGSHLITAGQDSRLRVWDATTGA 318
                  567788999**************************9985 PP

  == domain 4  score: 2.4 bits;  conditional E-value: 0.022
  ANAPC4_WD40  37 edsevrsLaWkpdgkl.....Lavaysdgevr 63 
                  + +++++LaW+ +g       L  a+ dg++r
   EEA21826.1 405 SAGRINGLAWRGNGGSgegleLFSAHGDGTIR 436
                  56899******997432222366777777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (480 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       267  (0.0148921); expected 358.6 (0.02)
Passed bias filter:                      231  (0.0128842); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 3260.72
//
Query:       EEA21827.1  [L=144]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (144 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       197  (0.0109878); expected 358.6 (0.02)
Passed bias filter:                      151  (0.00842211); expected 358.6 (0.02)
Passed Vit filter:                         9  (0.00050198); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.27s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 1036.72
//
Query:       EEA21828.1  [L=756]
Description: pH response protein PalF [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.4e-17   64.1   0.0      2e-16   60.4   0.0    2.6  2  Arrestin_N  Arrestin (or S-antigen), N-terminal domain
    1.4e-08   35.2   0.0    1.5e-05   25.4   0.0    3.2  2  Arrestin_C  Arrestin (or S-antigen), C-terminal domain


Domain annotation for each model (and alignments):
>> Arrestin_N  Arrestin (or S-antigen), N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.4   0.0   2.2e-20     2e-16       3     145 ..      38     190 ..      36     191 .. 0.87
   2 ?   -2.1   0.0       0.4   3.6e+03      98     128 ..     405     438 ..     404     444 .. 0.75

  Alignments for each domain:
  == domain 1  score: 60.4 bits;  conditional E-value: 2.2e-20
                 EEES-SEEEEETT--EEEEEEE-CCCCTT.CEEEEEEEEEEEESSSSTTTT...........CCCEEEEEEEEEEEEESTSSSSS.SSSSHHHHHHHH- CS
  Arrestin_N   3 ieldkrdevyhpgetvdGkvlleteelkkarkvkielsgkartgweeseva...........gktfrkdltlkkkqeyleteksllkskkdsqekLpkG 90 
                 ++ d +++ y+pg+ ++G+v+l+  ++++++ + ++l+g++++ +   +             g+ +r ++++ +  + l +++  + +   +  +L++G
  EEA21828.1  38 VQPDDPWRAYFPGDVIKGTVVLTVIKPIRITHLVVCLHGYVKVFKATVTPGeigpdigfvgpGRGRRPGEYMGNGLATLFEDEL-VLC---GDGRLKEG 132
                 677999************************************998865555899******998888888888877555444444.444...5799**** PP

                 TTEEEEEE---TT.S--SECSGEEEEEEEEEEEEECCC..E--C.CCEEEEEEEEEEB CS
  Arrestin_N  91 ehafpFsfelPkn.lpsSfeGkaggvrYevkvtldrpw..kidkkkkkvftVirkldl 145
                  ++f F ++lP++ lpsS+++++g++ Y++++tl+rp    +  ++ + +tV++ +d+
  EEA21828.1 133 IYKFKFELQLPPYkLPSSLNFERGTISYTITATLTRPItiSPTISCHRRITVLEDIDI 190
                 ***********9868***********************7777788*********9998 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.4
                 E---TTS--SE...CSGEEEEEEEEEEEEECCCE CS
  Arrestin_N  98 felPknlpsSf...eGkaggvrYevkvtldrpwk 128
                 +++P+++ +++    G+  + rY+v++++d   k
  EEA21828.1 405 IRIPEDAFPTItrvPGAMISFRYYVEAVIDLRGK 438
                 678888777765557899999******9997665 PP

>> Arrestin_C  Arrestin (or S-antigen), C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.0   0.0    0.0018        16      14     113 ..      45     167 ..      43     191 .. 0.69
   2 !   25.4   0.0   1.7e-09   1.5e-05       2     116 ..     287     437 ..     286     447 .. 0.78

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.0018
                 SEEETT--EEEEEEEEE-SSSEEEEEEEEEEEEEEEESS..........................SEEEEEEEEEEEEE---.....B-TTEE.EEEEE CS
  Arrestin_C  14 kgyvpGetipvtvkidndskkkvkkikvslvqhvdvcafnr........................snkkeknvvaksdsvkv.....tsaakdkletev 83 
                 ++y+pG+ i+ tv ++  +  ++ ++ v+l  +v+v+  +                          n+     +a+ + +++      + +++ +++++
  EEA21828.1  45 RAYFPGDVIKGTVVLTVIKPIRITHLVVCLHGYVKVFKATVtpgeigpdigfvgpgrgrrpgeymGNG-----LATLFEDELvlcgdGRLKEGIYKFKF 138
                 689***************************99999999877777777777777777776544433222.....22222222234444666777777778 PP

                 EE.----B-----S---EEEEEEEEEEEEE CS
  Arrestin_C  84 elqiPeeltpssarnvelikvsYklkvklt 113
                 elq+P+   pss  n e  ++sY++  +lt
  EEA21828.1 139 ELQLPPYKLPSSL-NFERGTISYTITATLT 167
                 8888844444554.7777788887777766 PP

  == domain 2  score: 25.4 bits;  conditional E-value: 1.7e-09
                 ---EEEEEEES-SEEETT--EEEEEEEE.E-SSSEEEEEEEEEEEEEEEESS....................................SEEEEEEEEEE CS
  Arrestin_C   2 dgkvsleaslpkkgyvpGetipvtvkid.ndskkkvkkikvslvqhvdvcafnr..................................snkkeknvvak 65 
                 +++++ +a l+++g  pG+tipv + i+ n   ++ + i ++l ++ ++  +                                    sn+ +++ + +
  EEA21828.1 287 EKTITATAELQRSGALPGDTIPVRIMINhNRQIRSPHGIIITLYRQGRIDIHPAiplgpsdaegkkvyedfipksrtglsglslgtsrSNSVFRKDLFQ 385
                 578999**********************88888************99888887788**99999888888888888888888887555544444444444 PP

                 EEE---....B-TTEE.EEEEEEE.----B--.---S---EEEEEEEEEEEEEEES CS
  Arrestin_C  66 sdsvkv....tsaakdkletevelqiPeeltp.ssarnvelikvsYklkvkltlsg 116
                 +    +      + + + + +++++iPe++ p  ++  + +i+ +Y+++ +++l g
  EEA21828.1 386 T----FapviIDPITMTATVKTTIRIPEDAFPtITRVPGAMISFRYYVEAVIDLRG 437
                 4....3455555555555666999********53446899************9985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (756 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       357  (0.0199119); expected 358.6 (0.02)
Passed bias filter:                      255  (0.0142228); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.26s 00:00:00.88 Elapsed: 00:00:00.45
# Mc/sec: 5031.04
//
Query:       EEA21829.1  [L=214]
Description: secretory component protein shr3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      4e-78  260.7   0.0    4.7e-78  260.5   0.0    1.0  1  SHR3_chaperone  ER membrane protein SH3
  ------ inclusion threshold ------
      0.017   15.1   0.3      0.027   14.4   0.0    1.5  2  DUF5453         Family of unknown function (DUF5453)
      0.035   13.0   3.4      0.059   12.3   3.5    1.4  1  MFS_1           Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> SHR3_chaperone  ER membrane protein SH3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  260.5   0.0   7.9e-82   4.7e-78       3     181 ..       6     197 ..       4     203 .. 0.97

  Alignments for each domain:
  == domain 1  score: 260.5 bits;  conditional E-value: 7.9e-82
  SHR3_chaperone   3 ssvataliigstsFflGvlfanfpyDynlLwssestee.afdaalehykflhaspplikrilhiviglgliglliklykpsednllFdgaSLvLy 96 
                      s+at+li+g+++FflG++f+ fpyDy+lLw+ e+t++ ++d++++h++flhasppli+rilhivi++g++g+l+klykpse+n+lFdgaSLvLy
      EEA21829.1   6 GSFATFLIVGPVCFFLGIVFSLFPYDYPLLWAGEPTPPsHYDYLEAHLRFLHASPPLIPRILHIVIFVGFAGMLAKLYKPSESNMLFDGASLVLY 100
                     69*******************************999999******************************************************** PP

  SHR3_chaperone  97 vvgvvvyitnivkglrtvtegawge............vdredslkvlaasntilalvLvGVlvLQaGqwYaerkeqeeleefeeeeaeeaaakae 179
                     v+gv+vyi+nivkglr v+ g +g+            ++redslkvlaasntilal+LvGVl+LQaGqwYae+k+q+e e+++++ +e++++k++
      EEA21829.1 101 VCGVTVYIANIVKGLRLVSGGIYGAelagneedaeqvLGREDSLKVLAASNTILALILVGVLILQAGQWYAEKKDQQEFEKLNQKSSESSSKKER 195
                     **********************************************************************************9999999998887 PP

  SHR3_chaperone 180 ek 181
                      +
      EEA21829.1 196 PE 197
                     65 PP

>> DUF5453  Family of unknown function (DUF5453)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.3       1.7     1e+04      45      64 ..      14      25 ..       8      33 .. 0.40
   2 ?   14.4   0.0   4.5e-06     0.027      76     164 ..      92     187 ..      53     201 .. 0.74

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 1.7
     DUF5453 45 itallGvvlgivlyffdvkf 64
                + +        v +f+ + f
  EEA21829.1 14 VGP--------VCFFLGIVF 25
                322........222222222 PP

  == domain 2  score: 14.4 bits;  conditional E-value: 4.5e-06
     DUF5453  76 fdkkytrvylsGvivfllnillgvlllvllvnfltnqileekysllltnalpllyssvG.vsivlslisiglsklarlfid......leklkakkd 164
                 fd    ++y+ Gv+v+++ni+ g+ l+   ++    +  ee+ +++l    +l   +   +  +l l+ + + +  +++ +       ekl +k  
  EEA21829.1  92 FDGASLVLYVCGVTVYIANIVKGLRLVSGGIYGAELAGNEEDAEQVLGREDSLKVLAASnTILALILVGVLILQAGQWYAEkkdqqeFEKLNQKSS 187
                 66666789************************9999999999999987776665444440445677888888888887776433333333333333 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   3.5   9.9e-06     0.059     152     254 ..       9     106 ..       3     171 .. 0.67

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 9.9e-06
       MFS_1 152 avfyilaivsllafvlfllllpeepperkrkspkeeekgtgpaplvp.awkallkdpvlw..illialllfffgfsglltllplylqevlglsglllag 247
                 a+f+i+++v++++++ ++ l+p ++p  +  +p++      +   ++ +++ l+++p+l   il i+++++f + +++  + p+   + + ++g+ l++
  EEA21829.1   9 ATFLIVGPVCFFLGI-VFSLFPYDYPLLWAGEPTPP----SHYDYLEaHLRFLHASPPLIprILHIVIFVGF-AGMLAKLYKPS--ESNMLFDGASLVL 99 
                 79***********99.569**************999....888888889********997645555555554.44445555555..4444444333333 PP

       MFS_1 248 lllalla 254
                 ++ +++ 
  EEA21829.1 100 YVCGVTV 106
                 3333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (214 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       967  (0.053935); expected 358.6 (0.02)
Passed bias filter:                      564  (0.0314574); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.40
# Mc/sec: 1590.51
//
Query:       EEA21830.1  [L=663]
Description: C6 sexual development transcription factor NosA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.5e-99  331.0   0.0    1.1e-98  330.5   0.0    1.1  1  Fungal_trans_2  Fungal specific transcription factor domain
    0.00018   21.6  13.4    0.00031   20.8  13.4    1.4  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  330.5   0.0  1.3e-102   1.1e-98       2     384 .]     245     663 .]     244     663 .] 0.95

  Alignments for each domain:
  == domain 1  score: 330.5 bits;  conditional E-value: 1.3e-102
  Fungal_trans_2   2 lldyyldnvapllspvpes...snpfrkvllplalsnkallhallalsafhlqskgpkds..lereakrykslalkelqealaelsstlsrneky 91 
                     ll++++dnv +l++p+ e+   +    + +l  +++nk++lh++l+++a+hl+s+ + ++  ++++++r++ +a+++l+++l+e+s++++     
      EEA21830.1 245 LLNHFVDNVLRLIFPIAEAhqgGLERARAVLHSLENNKSYLHCCLSVAAIHLKSTIGIEGevIDHDILRHRFEAVSQLCHSLNEDSEHEK----- 334
                     99******************9999******************************************************************..... PP

  Fungal_trans_2  92 kdiLaaiLllcsieissgdvsd......wrvhLeaatsliksrggs..kasssslsskarfllrifayldilssttlgrgpsfpseeyekllenk 178
                       iL a+L+++++++s+g ++d      w+ h++aatsli+++ ++  + +s++ + +++f++++ +++dil+st++g++p+f++++++k+l++ 
      EEA21830.1 335 --ILEATLAMIFFHCSVGGPDDhlpdiaWNDHFHAATSLINKLDLPnaLMQSNGAYTRPPFNMTLASWIDILGSTMIGKTPQFAHTYRSKHLSG- 426
                     ..*****************9999************************9999*******************************************. PP

  Fungal_trans_2 179 keesdsgldplmGcsnslilliseisrLarekrsarkdseleplsileeaseleqrllswkprssdlepdldeterassls...kdltelfrlaa 270
                        + sgl++lmGc++++++lisei++L++ + +   d    + + ++++++l q+l+ ++p +++le+++++ + a +++   k++t +fr+aa
      EEA21830.1 427 ---TPSGLRELMGCDDRVMYLISEIACLDALRAEGVVD----DMAVCSHVHALGQQLEFTEPADKSLETPYHPINGAIRPEqltKNITAVFRIAA 514
                     ...***********************************....***********************************9999999999******** PP

  Fungal_trans_2 271 liylyrlvlglppsspevqelvkkllellellpsspv.aiasLlWplFiaGceavde.ddRdfvrrrleele.qsrlgnvrrarqvleevWrrrd 362
                     +iyl++lv+g++++++++++lv++++++l+ +p +p   +++L+Wpl+iaG+ +v+  ++R+++++r+ e++ ++++g+++ra+++l+evWr +d
      EEA21830.1 515 RIYLCSLVPGFDRNQSSTMNLVDAITQALQVIPGGPEgYDRPLVWPLLIAGAFSVPTsSFRQVLHQRVIEMGdNADFGSFGRAYRLLQEVWRVAD 609
                     *********************************999999******************************************************** PP

  Fungal_trans_2 363 d................................geekidWrdvmekkgwellla 384
                     d                                +  +++Wrd+m+kkgw++ll+
      EEA21830.1 610 DpitpvsgdfpavsdfksdtytsplrsppmreiKKRNVHWRDIMQKKGWKYLLI 663
                     877777777777777776666666655555544444***************996 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8  13.4   3.4e-08   0.00031       2      36 ..      37      70 ..      36      74 .. 0.92

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 3.4e-08
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfyses 36
                +C +Cr ++ KCd+ +P+C+ C  l ++C+ y+++
  EEA21830.1 37 GCYTCRLRRKKCDESHPSCRTCNNLCVKCE-YERP 70
                6*****************************.9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (663 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       800  (0.0446204); expected 358.6 (0.02)
Passed bias filter:                      492  (0.0274416); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.31s 00:00:00.96 Elapsed: 00:00:00.47
# Mc/sec: 4207.16
//
Query:       EEA21831.1  [L=872]
Description: SAM and PH domain protein (Boi1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.6e-11   42.2   0.0    1.9e-10   40.7   0.0    1.9  2  SAM_2     SAM domain (Sterile alpha motif)
    3.6e-08   33.9   0.1    1.3e-07   32.1   0.1    2.1  1  PH        PH domain
    3.6e-08   33.7   0.2    2.1e-07   31.2   0.0    2.4  2  SAM_1     SAM domain (Sterile alpha motif)
    6.5e-05   22.7   0.0    0.00029   20.6   0.0    2.1  2  SAM_3     SAM domain (Sterile alpha motif)
  ------ inclusion threshold ------
          4    7.0  15.0       0.37   10.4  10.1    1.8  2  SR-25     Nuclear RNA-splicing-associated protein


Domain annotation for each model (and alignments):
>> SAM_2  SAM domain (Sterile alpha motif)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.7   0.0   5.4e-14   1.9e-10       1      66 []     180     245 ..     180     245 .. 0.97
   2 ?   -4.0   0.0       4.7   1.7e+04      38      51 ..     401     414 ..     401     416 .. 0.82

  Alignments for each domain:
  == domain 1  score: 40.7 bits;  conditional E-value: 5.4e-14
                 GGGHHHHHHHHHHHHTTT.GGGHHHHHHTTCSHHHHHTTSCHHHHHHTTHHHHHHHHHHHHHHHHHH CS
       SAM_2   1 veswsledvaeWLrsigl.kqytdnFrdagitgaelllrlteedLkrlGitsvghrkkilkkiqelk 66 
                 v sws++dv +W ++ g+   + ++F  + i+g  +ll l  edLk+l+i+s+g r++++++iq l+
  EEA21831.1 180 VRSWSPPDVVRWMQESGFdDSVIEKFFINDISG-AILLDLRSEDLKELDIQSFGKRRHVMNSIQHLR 245
                 679******************************.******************************985 PP

  == domain 2  score: -4.0 bits;  conditional E-value: 4.7
                 TSCHHHHHHTTHHH CS
       SAM_2  38 rlteedLkrlGits 51 
                 +++ee+L ++G+ +
  EEA21831.1 401 QISEEKLSEIGPRD 414
                 5799******9876 PP

>> PH  PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.1   0.1   3.6e-11   1.3e-07       2     101 ..     716     850 ..     715     854 .. 0.79

  Alignments for each domain:
  == domain 1  score: 32.1 bits;  conditional E-value: 3.6e-11
                 EEEEEEEEETSSSSC..SEEEEEEEEETTEEEEESST.TCTTESSEEEEEESTTEEEEEEEC...................TTSSSSTSEEEE...... CS
          PH   2 vkeGwLlkkgsgkkk..swkkrwfvLkdsellyyknd.ksekdkepkgsislsncevvevva...................tedpkrkfcfel...... 72 
                  ++Gw+ k++ ++     w++++f+Lk+++l++y+++  s +d++  + i++++  v                        +++ +  f f+l      
  EEA21831.1 716 THSGWMRKRKTTRMLrhEWEDHHFTLKGTRLAMYEDErASRRDSKAIEYIDVDDYAVACSSIpssskltaafkktvlkrksSAQDEAAFAFSLipapsg 814
                 689****999999889*********************75555555555555555555443337788888888889999876668888888888999999 PP

                 .........EESTSSSTEEEEEEESSHHHHHHHHHHHH CS
          PH  73 .........riverngsrtyllqasseeerkeWikaiq 101
                          ++v +ng +++++++++ +er +W++ + 
  EEA21831.1 815 kttgverrnVFV-SNG-KSHHFAVKTRDERIDWMRELM 850
                 998888876555.345.*****************9885 PP

>> SAM_1  SAM domain (Sterile alpha motif)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       1.4   4.8e+03      26      40 ..       7      21 ..       3      23 .. 0.87
   2 !   31.2   0.0     6e-11   2.1e-07       2      64 .]     182     245 ..     181     245 .. 0.95

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 1.4
                TTTSSHHHHTTSCHH CS
       SAM_1 26 ageidgdaLlllted 40
                 g++++++L+ l+++
  EEA21831.1  7 TGYVTLEMLQALSKQ 21
                589*********997 PP

  == domain 2  score: 31.2 bits;  conditional E-value: 6e-11
                 CTTHSSHHHHHHHTTS.GGGHHHHHTTTSSHHHHTTSCHHHHHHCTTTSHHHHHHHHHHHHHHH CS
       SAM_1   2 kwsvedVgeWLesigl.gqYadlFrageidgdaLlllteddLeklgvtllGHrkkIlyaIqrLk 64 
                 +ws+ dV++W+++ g+    +++F  + i+g  Ll+l ++dL++l + ++G r++ +++Iq+L+
  EEA21831.1 182 SWSPPDVVRWMQESGFdDSVIEKFFINDISGAILLDLRSEDLKELDIQSFGKRRHVMNSIQHLR 245
                 7***************9788899989999********************************996 PP

>> SAM_3  SAM domain (Sterile alpha motif)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.6   0.0   8.2e-08   0.00029      11      51 ..     184     226 ..     179     234 .. 0.91
   2 ?   -2.8   0.0       1.6   5.8e+03      12      26 ..     416     430 ..     406     431 .. 0.84

  Alignments for each domain:
  == domain 1  score: 20.6 bits;  conditional E-value: 8.2e-08
       SAM_3  11 tpeeVkaWLtakgFskktvesL..gklsGaqLfsLskeeLeqi 51 
                 +p +V +W+++ gF++ ++e++   ++sGa L+ L+ e+L+++
  EEA21831.1 184 SPPDVVRWMQESGFDDSVIEKFfiNDISGAILLDLRSEDLKEL 226
                 688******************86689**************975 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1.6
       SAM_3  12 peeVkaWLtakgFsk 26 
                 +e V+++L+ +++sk
  EEA21831.1 416 QENVRQYLNFQHLSK 430
                 6889****9999987 PP

>> SR-25  Nuclear RNA-splicing-associated protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4  10.1    0.0001      0.37      62     109 ..     255     298 ..     229     346 .. 0.52
   2 ?   -3.5   0.2       1.8   6.4e+03      92      92 ..     786     786 ..     747     813 .. 0.55

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.0001
       SR-25  62 rssssssssssssssssssssssssddrkkrgkkkdkkkkkkkkkkkk 109
                 +s+ss ++ss+  +sss s+s  ++d++kk+     +++++++ +kk+
  EEA21831.1 255 TSTSSHDHSSTDCTSSSESASTPTKDSNKKKH----RRRRNHRSHKKS 298
                 23333334444333333333333333322222....222222222222 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 1.8
       SR-25  92 r 92 
                  
  EEA21831.1 786 A 786
                 1 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (872 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       843  (0.0470188); expected 358.6 (0.02)
Passed bias filter:                      406  (0.0226449); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.72u 0.28s 00:00:01.00 Elapsed: 00:00:00.46
# Mc/sec: 5647.93
//
Query:       EEA21832.1  [L=1202]
Description: NACHT and Ankyrin domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.4e-60  199.7  13.5    7.6e-12   45.7   0.4    7.6  8  Ank_2     Ankyrin repeats (3 copies)
    9.1e-59  195.1  14.1    5.5e-12   46.0   0.1   11.6 13  Ank_4     Ankyrin repeats (many copies)
      3e-48  160.2  20.5    5.6e-08   32.9   0.1   13.2 13  Ank       Ankyrin repeat
    1.3e-44  145.0  17.4    1.2e-05   25.3   0.1   13.5 14  Ank_3     Ankyrin repeat
    9.4e-40  134.2  19.0    5.6e-08   32.9   0.0   10.0 12  Ank_5     Ankyrin repeats (many copies)
    9.1e-08   32.2   0.1    7.4e-07   29.2   0.0    2.6  3  NACHT     NACHT domain
    4.8e-07   30.3   0.1    2.9e-06   27.8   0.0    2.4  2  AAA_16    AAA ATPase domain
    3.6e-06   27.3   0.0    2.1e-05   24.8   0.0    2.4  2  AAA_22    AAA domain
  ------ inclusion threshold ------
      0.018   15.4   0.0      0.083   13.3   0.0    2.2  1  AAA       ATPase family associated with various cellular acti


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       2.6   5.1e+03      43      69 ..     410     442 ..     394     456 .. 0.62
   2 !   40.3   0.0   1.9e-13   3.7e-10      22      82 ..     641     710 ..     595     711 .. 0.80
   3 !   33.3   0.1   2.8e-11   5.6e-08      25      83 .]     713     778 ..     709     778 .. 0.87
   4 !   44.6   0.0   8.3e-15   1.6e-11      12      79 ..     763     841 ..     757     845 .. 0.86
   5 !   45.7   0.4   3.8e-15   7.6e-12       1      81 [.     786     876 ..     786     878 .. 0.86
   6 !   38.2   0.4   8.1e-13   1.6e-09       1      81 [.     852     943 ..     852     945 .. 0.83
   7 !   14.3   0.0   2.2e-05     0.045      38      81 ..     962    1021 ..     944    1023 .. 0.81
   8 !   43.2   0.1   2.3e-14   4.5e-11      12      82 ..    1008    1092 ..    1002    1093 .. 0.82

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 2.6
       Ank_2  43 klLleh..ad...ndgrtpL.hyAarsghleiv 69 
                 ++Ll++  +d   ++ + +L h A ++  +++v
  EEA21832.1 410 SFLLAQlhLDllaSYEEKALaHSALSHLPENLV 442
                 344443554455677888997888766444444 PP

  == domain 2  score: 40.3 bits;  conditional E-value: 1.9e-13
       Ank_2  22 pnk..ngktaLhyAakngnleiv...klLleh...ad....ndgrtpLhyAarsghleivklLlekgadinlk 82 
                 +++  +++t+Lhy a     +iv   k Lle+   +d      g tpLh+Aa+ g++++++lLl++gadin++
  EEA21832.1 641 IGHypTDWTPLHYLAYF---DIVcrgKRLLEQnteVDindnALGVTPLHCAAFRGNEDMLELLLDNGADINAQ 710
                 3323578*********9...676689****9777744534444*********99*****************87 PP

  == domain 3  score: 33.3 bits;  conditional E-value: 2.8e-11
       Ank_2  25 ngktaLhyAakngnleivklLleh......adndgrtpLhyAars.ghleivklLlekgadinlkd 83 
                 +g taLh+A+ +g++ i+k L++       ++n g+t+Lh+A+   + + +v lL++++ d+n+++
  EEA21832.1 713 DGDTALHLATVRGKRRIMKVLIARgidttkTNNAGHTALHAAVGTpDDEATVPLLVKSKLDVNAQN 778
                 799*******************966666667799*********778788*******8899999875 PP

  == domain 4  score: 44.6 bits;  conditional E-value: 8.3e-15
       Ank_2  12 lvklLl.egadpn..k..ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadi 79 
                 +v lL+ ++ d+n  +  +g t+Lh+A++     i+ +Ll++      ++++g+tpLh++a s++le+v lLle+ga +
  EEA21832.1 763 TVPLLVkSKLDVNaqNsvTGDTPLHLAVQFKRPRILLYLLNKkalvdtFNKKGMTPLHISAHSNNLEAVTLLLERGAIV 841
                 678888888899985379************999*******977896666699*********************999855 PP

  == domain 5  score: 45.7 bits;  conditional E-value: 3.8e-15
       Ank_2   1 LhlAakngnlelvklLl.egadpn...kngktaLhyAakngnleivklLleh...ad...ndgrtpLhyAarsghleivklLlekgadinl 81 
                 LhlA++++ + ++ +Ll ++a ++   k+g+t+Lh++a+++nle+v lLle    ++   ++g t++h+Aa+  +  ++++L+  gadin+
  EEA21832.1 786 LHLAVQFKRPRILLYLLnKKALVDtfnKKGMTPLHISAHSNNLEAVTLLLERgaiVEsraSNGITAMHVAAQAENWIAFDFLVAAGADINA 876
                 8*****99899*****9755555555459*********************977783344689*********999989999***99****96 PP

  == domain 6  score: 38.2 bits;  conditional E-value: 8.1e-13
       Ank_2   1 LhlAakngnlelvklLl.egadpn..k.ngktaLhyAakng.nleivklLleh......adndgrtpLhyAarsghleivklLlekgadinl 81 
                 +h+Aa+ +n  ++++L+ +gad+n  + ng t Lh+ a ++ +  i   Lle+       +++g+tpL++Aa +g+ e++ lLle ga+i +
  EEA21832.1 852 MHVAAQAENWIAFDFLVaAGADINawDlNGDTLLHTRANKQrDSAITTKLLEFganfeaRNSKGYTPLQAAALNGNREMFFLLLEAGANIAV 943
                 69999986455999999*******8769*******77776525577899**977566655599**********************9**9975 PP

  == domain 7  score: 14.3 bits;  conditional E-value: 2.2e-05
       Ank_2   38 nleivklLleh...ad...ndgrtpLhyAarsg..........hleivklLlekgadinl 81  
                  +lei+++Ll+    +d   ++g+ p+h Aa++g          + e +++L+ +gad+n+
  EEA21832.1  962 YLEILRALLARglsVDalsSQGWKPIHQAAFKGtgspditldrSREHLEILISYGADVNA 1021
                  5799*****977775566699*********9977788888888779999***99****97 PP

  == domain 8  score: 43.2 bits;  conditional E-value: 2.3e-14
       Ank_2   12 lvklLl.egadpn...k..ngktaLhyAakngnl.ei.vklLleh...ad...ndgrtpLhyAarsghleivklLlekgadinlk 82  
                   +++L+ +gad+n   +  + +taLh+A+++     + + lLl+h   ++    +g+t+Lh+Aa  g++ ++++Lle+gadi +k
  EEA21832.1 1008 HLEILIsYGADVNavtEsdERETALHLATRASIPrPLfIMLLLDHgadVNaknGEGKTALHLAAARGRETLFRILLEHGADISIK 1092
                  57889999****988625799*********974322259*****9966335446699*******99****************987 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0      0.47   9.5e+02      35      45 ..     647     657 ..     583     658 .. 0.71
   2 !   27.5   0.1   1.7e-09   3.4e-06       3      55 .]     649     701 ..     647     701 .. 0.90
   3 !   46.0   0.1   2.8e-15   5.5e-12       3      55 .]     683     734 ..     681     734 .. 0.96
   4 !    8.4   0.0    0.0017       3.3      16      43 ..     729     755 ..     723     757 .. 0.89
   5 !   27.9   0.0   1.2e-09   2.5e-06       2      55 .]     748     802 ..     747     802 .. 0.92
   6 !   23.0   0.1   4.3e-08   8.7e-05      13      55 .]     794     835 ..     792     835 .. 0.93
   7 !   23.9   0.1   2.3e-08   4.5e-05       1      47 [.     815     860 ..     815     864 .. 0.94
   8 !   14.4   0.2   2.2e-05     0.043       3      40 ..     850     886 ..     850     889 .. 0.94
   9 !   25.5   0.1     7e-09   1.4e-05       3      55 .]     883     935 ..     882     935 .. 0.93
  10 !   17.4   0.0   2.4e-06    0.0049      12      46 ..     961     994 ..     957    1001 .. 0.89
  11 !   10.9   0.0   0.00027      0.55      17      44 ..    1009    1037 ..    1007    1039 .. 0.80
  12 !   30.5   0.1   1.9e-10   3.9e-07      17      55 .]    1046    1083 ..    1042    1083 .. 0.92
  13 !    9.3   0.0   0.00085       1.7       6      30 ..    1068    1092 ..    1068    1095 .. 0.90

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.47
       Ank_4  35 GetalhiAakr 45 
                 ++t+lh+ a++
  EEA21832.1 647 DWTPLHYLAYF 657
                 68888887775 PP

  == domain 2  score: 27.5 bits;  conditional E-value: 1.7e-09
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 t+Lhy+a++  +   ++Lle++ +++  dn+ G t+lh+Aa rgn ++l+lLl
  EEA21832.1 649 TPLHYLAYFDIVCRGKRLLEQNTEVDINDNALGVTPLHCAAFRGNEDMLELLL 701
                 78888888888888899**9998888888***********************8 PP

  == domain 3  score: 46.0 bits;  conditional E-value: 2.8e-15
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 t+Lh aa  g++++++lLl++gadinaq  ++G+talh A  rg+ +i k L+
  EEA21832.1 683 TPLHCAAFRGNEDMLELLLDNGADINAQ-TKDGDTALHLATVRGKRRIMKVLI 734
                 89**************************.***************999999997 PP

  == domain 4  score: 8.4 bits;  conditional E-value: 0.0017
       Ank_4  16 lvrlLlekgadinaqdnrsGetalhiAa 43 
                 + + L+++g+d  ++ n+ G talh A+
  EEA21832.1 729 IMKVLIARGIDTTKT-NNAGHTALHAAV 755
                 6789*******9999.***********8 PP

  == domain 5  score: 27.9 bits;  conditional E-value: 1.2e-09
       Ank_4   2 ltaLhyaai.sgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +taLh+a+    ++ +v lL+ ++ d+naq +  G+t+lh A+++ +++il +Ll
  EEA21832.1 748 HTALHAAVGtPDDEATVPLLVKSKLDVNAQNSVTGDTPLHLAVQFKRPRILLYLL 802
                 699******888888899************5577*******************98 PP

  == domain 6  score: 23.0 bits;  conditional E-value: 4.3e-08
       Ank_4  13 rlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 r +++ +Ll+k+a ++   n+ G+t+lhi a  +n+e++ lLl
  EEA21832.1 794 RPRILLYLLNKKALVDTF-NKKGMTPLHISAHSNNLEAVTLLL 835
                 5677889***********.**********************98 PP

  == domain 7  score: 23.9 bits;  conditional E-value: 2.3e-08
       Ank_4   1 eltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgn 47 
                 ++t+Lh  a+s++le+v lLle+ga +  +  ++G ta+h Aa+ +n
  EEA21832.1 815 GMTPLHISAHSNNLEAVTLLLERGAIVESR-ASNGITAMHVAAQAEN 860
                 69****************************.677*********9887 PP

  == domain 8  score: 14.4 bits;  conditional E-value: 2.2e-05
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalh 40 
                 ta+h aa++++  + ++L++ gadina+ + +G+t+lh
  EEA21832.1 850 TAMHVAAQAENWIAFDFLVAAGADINAW-DLNGDTLLH 886
                 689999999999999*************.********9 PP

  == domain 9  score: 25.5 bits;  conditional E-value: 7e-09
       Ank_4   3 taLhyaaisgrlelvrlLl.ekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 t+Lh +a+++r  ++   l e+ga+  a+ n+ G t+l+ Aa++gn e++ lLl
  EEA21832.1 883 TLLHTRANKQRDSAITTKLlEFGANFEAR-NSKGYTPLQAAALNGNREMFFLLL 935
                 89************996665*********.********************9997 PP

  == domain 10  score: 17.4 bits;  conditional E-value: 2.4e-06
       Ank_4  12 grlelvrlLlekgadinaqdnrsGetalhiAakrg 46 
                   le++r Ll++g +++a  +++G+ ++h Aa +g
  EEA21832.1 961 AYLEILRALLARGLSVDAL-SSQGWKPIHQAAFKG 994
                 5799**************9.************888 PP

  == domain 11  score: 10.9 bits;  conditional E-value: 0.00027
       Ank_4   17 vrlLlekgadinaq.dnrsGetalhiAak 44  
                  +++L+++gad+na+  +++ etalh A +
  EEA21832.1 1009 LEILISYGADVNAVtESDERETALHLATR 1037
                  678***********4445566*****965 PP

  == domain 12  score: 30.5 bits;  conditional E-value: 1.9e-10
       Ank_4   17 vrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  ++lLl++gad+na  n++G talh Aa rg+   ++ Ll
  EEA21832.1 1046 IMLLLDHGADVNAK-NGEGKTALHLAAARGRETLFRILL 1083
                  689**********9.****************98888776 PP

  == domain 13  score: 9.3 bits;  conditional E-value: 0.00085
       Ank_4    6 hyaaisgrlelvrlLlekgadinaq 30  
                  h aa+ gr+ l r+Lle+gadi   
  EEA21832.1 1068 HLAAARGRETLFRILLEHGADISIK 1092
                  889******************9876 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0     0.037        74       3      22 ..     648     667 ..     647     678 .. 0.64
   2 !   32.9   0.1   2.8e-11   5.6e-08       2      32 .]     681     712 ..     680     712 .. 0.95
   3 !   17.6   0.0     2e-06    0.0039       1      32 []     713     745 ..     713     745 .. 0.92
   4 !    7.7   0.1    0.0025         5       2      31 ..     747     778 ..     746     779 .. 0.84
   5 !   13.9   0.0   2.8e-05     0.056       2      22 ..     782     802 ..     781     812 .. 0.86
   6 !   16.1   0.0   5.6e-06     0.011       2      25 ..     815     839 ..     814     844 .. 0.92
   7 !    9.8   0.0   0.00055       1.1       1      29 [.     847     876 ..     847     879 .. 0.79
   8 ?    2.9   0.0     0.084   1.7e+02       1      31 [.     880     912 ..     880     913 .. 0.68
   9 !   13.2   0.0   4.8e-05     0.096       2      28 ..     915     942 ..     914     945 .. 0.92
  10 ?   -1.9   0.0       2.7   5.5e+03      10      29 ..     958     978 ..     948     981 .. 0.68
  11 ?    5.1   0.0     0.017        35      16      31 ..    1007    1023 ..     983    1024 .. 0.62
  12 !   19.8   0.1   3.9e-07   0.00078       4      31 ..    1030    1060 ..    1028    1060 .. 0.85
  13 !   18.0   0.0   1.5e-06    0.0029       2      29 ..    1063    1091 ..    1062    1093 .. 0.91

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.037
                 BBHHHHHHHHTTHHHH...HHHH CS
         Ank   3 nTPLHlAatngkkrii...klLL 22 
                 +TPLH+ a+++   i+   k LL
  EEA21832.1 648 WTPLHYLAYFD---IVcrgKRLL 667
                 7****988777...774544455 PP

  == domain 2  score: 32.9 bits;  conditional E-value: 2.8e-11
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlnaldn 32 
                 G TPLH+Aa +g++++++lLL +GA++na+++
  EEA21832.1 681 GVTPLHCAAFRGNEDMLELLLdNGADINAQTK 712
                 99*******************88******985 PP

  == domain 3  score: 17.6 bits;  conditional E-value: 2e-06
                 TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hGAnlnaldn 32 
                 dG+T+LHlA  +gk ri k L+ +G + + ++n
  EEA21832.1 713 DGDTALHLATVRGKRRIMKVLIaRGIDTTKTNN 745
                 8*******9989**********88999988886 PP

  == domain 4  score: 7.7 bits;  conditional E-value: 0.0025
                 SBBHHHHHH.HHTTHHHHHHHH.TTTSTTCBT CS
         Ank   2 GnTPLHlAa.tngkkriiklLL.hGAnlnald 31 
                 G+T+LH A+ t++++  + lL+ +  ++na++
  EEA21832.1 747 GHTALHAAVgTPDDEATVPLLVkSKLDVNAQN 778
                 99*****9999999889999984446999998 PP

  == domain 5  score: 13.9 bits;  conditional E-value: 2.8e-05
                 SBBHHHHHHHHTTHHHHHHHH CS
         Ank   2 GnTPLHlAatngkkriiklLL 22 
                 G+TPLHlA++++ +ri+ +LL
  EEA21832.1 782 GDTPLHLAVQFKRPRILLYLL 802
                 9***************99999 PP

  == domain 6  score: 16.1 bits;  conditional E-value: 5.6e-06
                 SBBHHHHHHHHTTHHHHHHHH.TTT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGA 25 
                 G+TPLH+ a+ ++++ + lLL +GA
  EEA21832.1 815 GMTPLHISAHSNNLEAVTLLLeRGA 839
                 9********99**********8898 PP

  == domain 7  score: 9.8 bits;  conditional E-value: 0.00055
                 TSBBHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hGAnlna 29 
                 +G T+ H+Aa+  ++    +L+  GA++na
  EEA21832.1 847 NGITAMHVAAQAENWIAFDFLVaAGADINA 876
                 7*********66666666667788*****9 PP

  == domain 8  score: 2.9 bits;  conditional E-value: 0.084
                 TSBBHHH.HHH.HHTTHHHHHHHH.TTTSTTCBT CS
         Ank   1 dGnTPLH.lAa.tngkkriiklLL.hGAnlnald 31 
                 +G+T LH +A  +++   i+  LL  GAn  a++
  EEA21832.1 880 NGDTLLHtRANkQRD-SAITTKLLeFGANFEARN 912
                 7******88444333.345555897799987776 PP

  == domain 9  score: 13.2 bits;  conditional E-value: 4.8e-05
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnln 28 
                 G+TPL  Aa ng+ ++  lLL  GAn++
  EEA21832.1 915 GYTPLQAAALNGNREMFFLLLeAGANIA 942
                 9********************88***97 PP

  == domain 10  score: -1.9 bits;  conditional E-value: 2.7
                 HHHTTHHHHHHHH.TTTSTTC CS
         Ank  10 atngkkriiklLL.hGAnlna 29 
                 ++++ ++i+++LL +G +++a
  EEA21832.1 958 VNEAYLEILRALLaRGLSVDA 978
                 45566789*****87855666 PP

  == domain 11  score: 5.1 bits;  conditional E-value: 0.017
                  HHHHHHH.TTTSTTCBT CS
         Ank   16 riiklLL.hGAnlnald 31  
                  + ++ L+ +GA++na++
  EEA21832.1 1007 EHLEILIsYGADVNAVT 1023
                  467789988******97 PP

  == domain 12  score: 19.8 bits;  conditional E-value: 3.9e-07
                  BHHHHHHHHTT...HHHHHHHH.TTTSTTCBT CS
         Ank    4 TPLHlAatngk...kriiklLL.hGAnlnald 31  
                  T+LHlA  +++   +  i lLL hGA++na++
  EEA21832.1 1030 TALHLAT-RASiprPLFIMLLLdHGADVNAKN 1060
                  *****64.555566****************97 PP

  == domain 13  score: 18.0 bits;  conditional E-value: 1.5e-06
                  SBBHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAnlna 29  
                  G T+LHlAa +g +   + LL hGA++ +
  EEA21832.1 1063 GKTALHLAAARGRETLFRILLeHGADISI 1091
                  9********899999***********976 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.2         9   1.8e+04       5      14 ..      10      19 ..      10      25 .. 0.75
   2 ?    5.1   0.0     0.022        44       3      29 ..     648     675 ..     646     677 .. 0.82
   3 !   25.3   0.1   5.8e-09   1.2e-05       2      31 .]     681     709 ..     680     709 .. 0.95
   4 !   12.2   0.0   0.00011      0.21       1      28 [.     713     739 ..     713     741 .. 0.95
   5 ?    1.3   0.0      0.39   7.8e+02       2      30 ..     747     775 ..     746     776 .. 0.79
   6 !   13.8   0.0   3.2e-05     0.064       2      27 ..     782     806 ..     781     810 .. 0.88
   7 !   15.2   0.0   1.1e-05     0.023       2      27 ..     815     839 ..     814     842 .. 0.92
   8 !   14.9   0.1   1.4e-05     0.028       1      31 []     847     876 ..     847     876 .. 0.96
   9 ?    1.2   0.0      0.42   8.4e+02       1      29 [.     880     908 ..     880     910 .. 0.81
  10 !   15.3   0.0   1.1e-05     0.021       2      30 ..     915     942 ..     914     943 .. 0.92
  11 ?   -2.4   0.0       6.1   1.2e+04      16      30 ..     964     977 ..     959     978 .. 0.79
  12 ?    6.1   0.0      0.01        20       2      31 .]     983    1021 ..     982    1021 .. 0.80
  13 !   10.8   0.0   0.00031      0.62       3      31 .]    1029    1058 ..    1027    1058 .. 0.89
  14 !   20.9   0.0   1.7e-07   0.00033       1      31 []    1062    1091 ..    1062    1091 .. 0.94

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 9
       Ank_3  5 pLhlAarsgn 14
                +Lh+ +r+ +
  EEA21832.1 10 LLHQLCRHVR 19
                6999999855 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.022
       Ank_3   3 etpLhlAarsgnleivkfLle.nkgadv 29 
                 +tpLh+ a ++ +++ k Lle n  +d+
  EEA21832.1 648 WTPLHYLAYFDIVCRGKRLLEqNTEVDI 675
                 9************999999995555555 PP

  == domain 3  score: 25.3 bits;  conditional E-value: 5.8e-09
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvna 31 
                 G tpLh+Aa  gn +++++Ll+ +gad+na
  EEA21832.1 681 GVTPLHCAAFRGNEDMLELLLD-NGADINA 709
                 78********************.8****96 PP

  == domain 4  score: 12.2 bits;  conditional E-value: 0.00011
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgad 28 
                 +G t+LhlA   g+  i+k L+  +g+d
  EEA21832.1 713 DGDTALHLATVRGKRRIMKVLIA-RGID 739
                 699********************.9*99 PP

  == domain 5  score: 1.3 bits;  conditional E-value: 0.39
       Ank_3   2 GetpLhlAarsgnle.ivkfLlenkgadvn 30 
                 G t+Lh A+   + e  v +L++    dvn
  EEA21832.1 747 GHTALHAAVGTPDDEaTVPLLVK-SKLDVN 775
                 89******998888755888888.677777 PP

  == domain 6  score: 13.8 bits;  conditional E-value: 3.2e-05
       Ank_3   2 GetpLhlAarsgnleivkfLlenkga 27 
                 G tpLhlA+ + ++ i+ +Ll+ k a
  EEA21832.1 782 GDTPLHLAVQFKRPRILLYLLN-KKA 806
                 89*******************9.665 PP

  == domain 7  score: 15.2 bits;  conditional E-value: 1.1e-05
       Ank_3   2 GetpLhlAarsgnleivkfLlenkga 27 
                 G+tpLh+ a+s+nle v +Lle +ga
  EEA21832.1 815 GMTPLHISAHSNNLEAVTLLLE-RGA 839
                 99********************.887 PP

  == domain 8  score: 14.9 bits;  conditional E-value: 1.4e-05
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvna 31 
                 nG t++h+Aa + n    +fL+   gad+na
  EEA21832.1 847 NGITAMHVAAQAENWIAFDFLVA-AGADINA 876
                 799********************.9****96 PP

  == domain 9  score: 1.2 bits;  conditional E-value: 0.42
       Ank_3   1 nGetpLh.lAarsgnleivkfLlenkgadv 29 
                 nG t+Lh +A ++ + +i   Lle +ga++
  EEA21832.1 880 NGDTLLHtRANKQRDSAITTKLLE-FGANF 908
                 799****77777777779999999.99986 PP

  == domain 10  score: 15.3 bits;  conditional E-value: 1.1e-05
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G+tpL  Aa++gn e+  +Lle  ga++ 
  EEA21832.1 915 GYTPLQAAALNGNREMFFLLLE-AGANIA 942
                 9**************9999999.899985 PP

  == domain 11  score: -2.4 bits;  conditional E-value: 6.1
       Ank_3  16 eivkfLlenkgadvn 30 
                 ei+++Ll  +g  v+
  EEA21832.1 964 EILRALLA-RGLSVD 977
                 799****9.888776 PP

  == domain 12  score: 6.1 bits;  conditional E-value: 0.01
       Ank_3    2 GetpLhlAarsgnl..ei........vkfLlenkgadvna 31  
                  G+ p+h+Aa  g    +i        ++ L+  +gadvna
  EEA21832.1  983 GWKPIHQAAFKGTGspDItldrsrehLEILIS-YGADVNA 1021
                  89999999999999762445666677******.*****96 PP

  == domain 13  score: 10.8 bits;  conditional E-value: 0.00031
       Ank_3    3 etpLhlAarsgnle.ivkfLlenkgadvna 31  
                  et+LhlA r+  +  + ++Ll  +gadvna
  EEA21832.1 1029 ETALHLATRASIPRpLFIMLLLDHGADVNA 1058
                  8************66999999999****96 PP

  == domain 14  score: 20.9 bits;  conditional E-value: 1.7e-07
       Ank_3    1 nGetpLhlAarsgnleivkfLlenkgadvna 31  
                  +G t+LhlAa  g+ ++ + Lle +gad+ +
  EEA21832.1 1062 EGKTALHLAAARGRETLFRILLE-HGADISI 1091
                  599********************.9***975 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       3.7   7.4e+03      16      25 ..     648     656 ..     644     658 .. 0.74
   2 !   32.6   0.7   3.4e-11   6.8e-08       7      56 .]     673     721 ..     666     721 .. 0.86
   3 !    5.8   0.0     0.009        18      27      54 ..     725     752 ..     724     754 .. 0.85
   4 !   12.6   0.1   6.5e-05      0.13       1      56 []     733     789 ..     733     789 .. 0.96
   5 !   10.8   0.0   0.00024      0.48      13      38 ..     781     804 ..     771     809 .. 0.78
   6 !   25.1   0.1   7.9e-09   1.6e-05       1      56 []     801     855 ..     801     855 .. 0.94
   7 !   15.4   0.2   8.5e-06     0.017       1      54 [.     834     886 ..     834     887 .. 0.94
   8 !   21.5   0.1   1.1e-07   0.00021       1      54 [.     867     920 ..     867     922 .. 0.96
   9 !   13.6   0.0   3.3e-05     0.066       1      51 [.     901     950 ..     901     954 .. 0.88
  10 !    6.7   0.0    0.0045       9.1       1      54 [.     934     988 ..     934     990 .. 0.78
  11 ?    3.5   0.0     0.048        95       1      23 [.    1012    1035 ..    1012    1038 .. 0.90
  12 !   32.9   0.0   2.8e-11   5.6e-08       1      45 [.    1049    1092 ..    1049    1095 .. 0.96

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 3.7
       Ank_5  16 gntpLhvAak 25 
                 + tpLh+ a+
  EEA21832.1 648 W-TPLHYLAY 656
                 3.99999886 PP

  == domain 2  score: 32.6 bits;  conditional E-value: 3.4e-11
       Ank_5   7 advnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 +d+n++   g+tpLh Aa +g+ d+++lLl++gad+n+++++G+tal+lA
  EEA21832.1 673 VDINDNA-LGVTPLHCAAFRGNEDMLELLLDNGADINAQTKDGDTALHLA 721
                 5666655.479*************************************98 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.009
       Ank_5  27 gaadvvrlLlargadlnltdsrGltald 54 
                 g  +++++L+arg d++ t++ G tal+
  EEA21832.1 725 GKRRIMKVLIARGIDTTKTNNAGHTALH 752
                 5667999999999999999999999997 PP

  == domain 4  score: 12.6 bits;  conditional E-value: 6.5e-05
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrG.ltaldlA 56 
                 L+++g +d+  +++ g t+Lh A+     +    Ll +  +d n+++s   +t+l+lA
  EEA21832.1 733 LIARG-IDTTKTNNAGHTALHAAVGTPDDEATVPLLvKSKLDVNAQNSVTgDTPLHLA 789
                 78999.*************************999999***********999*****98 PP

  == domain 5  score: 10.8 bits;  conditional E-value: 0.00024
       Ank_5  13 dgggntpLhvAakygaadvvrlLlar 38 
                  g+  tpLh+A+   +++++++Ll+ 
  EEA21832.1 781 TGD--TPLHLAVQFKRPRILLYLLNK 804
                 333..*******************54 PP

  == domain 6  score: 25.1 bits;  conditional E-value: 7.9e-09
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 Ll++  a v++ +++g+tpLh++a+ ++++ v lLl+rga    + s+G ta+++A
  EEA21832.1 801 LLNKK-ALVDTFNKKGMTPLHISAHSNNLEAVTLLLERGAIVESRASNGITAMHVA 855
                 67777.99********************************************9998 PP

  == domain 7  score: 15.4 bits;  conditional E-value: 8.5e-06
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltald 54 
                 Lle+g a v  +  +g t++hvAa + ++  + +L+a gad+n+ d +G+t+l+
  EEA21832.1 834 LLERG-AIVESRASNGITAMHVAAQAENWIAFDFLVAAGADINAWDLNGDTLLH 886
                 78999.99999999999******************************9999986 PP

  == domain 8  score: 21.5 bits;  conditional E-value: 1.1e-07
       Ank_5   1 LlehgpadvnrldgggntpLhvAak.ygaadvvrlLlargadlnltdsrGltald 54 
                 L+++g ad+n++d +g t Lh+ a+ ++ + +  +Ll++ga+  +++s G+t+l+
  EEA21832.1 867 LVAAG-ADINAWDLNGDTLLHTRANkQRDSAITTKLLEFGANFEARNSKGYTPLQ 920
                 78999.***********************************************98 PP

  == domain 9  score: 13.6 bits;  conditional E-value: 3.3e-05
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGlt 51 
                 Lle g a+  +++ +g+tpL  Aa +g+ +++ lLl+ ga++ + +  G++
  EEA21832.1 901 LLEFG-ANFEARNSKGYTPLQAAALNGNREMFFLLLEAGANIAVETPKGEN 950
                 78888.99999*************************999999888887755 PP

  == domain 10  score: 6.7 bits;  conditional E-value: 0.0045
       Ank_5   1 LlehgpadvnrldgggntpLhvA..akygaadvvrlLlargadlnltdsrGltald 54 
                 Lle+g a++  + ++g++ Lh+   ++  +++++r Llarg++ ++  s+G+ +++
  EEA21832.1 934 LLEAG-ANIAVETPKGENMLHITppVNEAYLEILRALLARGLSVDALSSQGWKPIH 988
                 67777.5555566667777777555778899********************99875 PP

  == domain 11  score: 3.5 bits;  conditional E-value: 0.048
       Ank_5    1 Llehg.padvnrldgggntpLhvA 23  
                  L+++g +++  ++  +++t+Lh+A
  EEA21832.1 1012 LISYGaDVNAVTESDERETALHLA 1035
                  789999999999999999****99 PP

  == domain 12  score: 32.9 bits;  conditional E-value: 2.8e-11
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnlt 45  
                  Ll+hg advn+++g+g t+Lh+Aa +g+ +++r+Ll++gad+ ++
  EEA21832.1 1049 LLDHG-ADVNAKNGEGKTALHLAAARGRETLFRILLEHGADISIK 1092
                  8****.***********************************9876 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       1.5     3e+03     120     153 ..     118     152 ..     104     156 .. 0.73
   2 !   29.2   0.0   3.7e-10   7.4e-07       5     131 ..     214     351 ..     210     382 .. 0.81
   3 ?   -3.4   0.0       3.9   7.8e+03      68      93 ..     492     523 ..     462     543 .. 0.65

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.5
                 --EEEEEEECCCHHHHCTTSSCE...EEEE--TCC CS
       NACHT 120 easllltvrpralrdleeqleea.ivlevegfses 153
                 ++ +ll++++++ + +e+++ e+ i+  ++ f e 
  EEA21832.1 118 KVAFLLATQTDSPSSMERSITETdIYQRLRQFHEM 152
                 56678888888888888888888777777777765 PP

  == domain 2  score: 29.2 bits;  conditional E-value: 3.7e-10
                 EEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-...-HCHHHCCCCTS--SSS-C.......................CHHHHCCSC CS
       NACHT   5 lqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgnarsladllfsqlpepaapvse.......................vwavllelp 80 
                   G+aG+GKT L   +++ +++     + +  vF ++ +e   ++ ++ l + + +ql    ++ s+                        +   + ++
  EEA21832.1 214 CIGPAGIGKTFLSSVIIDHLQRTFTSPD-VAIVFIFCHKEKDGENSCPVLLQSVLAQLIYRRRALSQstealynfeaasgakasskayqnAIRAEVNHF 311
                 57******************99887776.79*****999999999885555555555555555555557788999999999999999988777788999 PP

                 CCEEEEEE-STT-SS-TCH.........HHHHHCTTTTT--EEEEEEECCC CS
       NACHT  81 erlLlilDglDelvtdlgqkekqpvrtlLselirkkllpeasllltvrpra 131
                  ++ l++DglD +++ +++         L + ++k l+  + ll+t+r ++
  EEA21832.1 312 SKVFLVIDGLDTISDRDRF---------L-NRMQK-LPEHTQLLITLRESS 351
                 9999**********98888.........4.55565.777888888888765 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 3.9
                 SS-CCHHHHCCSCCCEE......EEEE-STT- CS
       NACHT  68 pvsevwavllelperlL......lilDglDel 93 
                 ++++  + l++ ++rlL      l++D++  +
  EEA21832.1 492 DSDQSGSDLTSFETRLLsetcglLTIDAVTGT 523
                 44443444555555555555555999987655 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0   1.5e-09   2.9e-06      14     152 ..     199     329 ..     195     347 .. 0.65
   2 ?   -3.2   0.0       4.7   9.4e+03      61     107 ..     438     481 ..     410     514 .. 0.52

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 1.5e-09
      AAA_16  14 salervrsgrpelvllsGesGvGKsslvrellralekd......ggiflrgkcdqlesa.ipy...salaqalareellrqlldeaesaeleawrekle 102
                 + ++++++g+ ++++++G++G+GK+ l   + ++l+++       ++f+ ++ ++ +++  p    s+laq++ r++ l q  +++ + e++  +++  
  EEA21832.1 199 QQYRQWSQGSFRSLYCIGPAGIGKTFLSSVIIDHLQRTftspdvAIVFIFCHKEKDGENsCPVllqSVLAQLIYRRRALSQSTEALYNFEAASGAKASS 297
                 568999*********************999999999999999765677888888885553554443346666655444444444433333333333333 PP

      AAA_16 103 ealaavpelagaeasrllellkrllallsrderplvlvlDdlqwadeasl 152
                               ++  +++++ ++  s+    + lv+D l+ + + ++
  EEA21832.1 298 --------------KAYQNAIRAEVNHFSK----VFLVIDGLDTISDRDR 329
                 ..............4555555555555555....9999999998877554 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 4.7
      AAA_16  61 dqlesaipysalaqalareellrqllde.aesaeleawrekleeala......a 107
                  ++        l+++  + e+++ +l++ ++s+++ +w  ++++ l+      a
  EEA21832.1 438 PEN--------LVETY-A-EIMKRILSKhPRSRNFIYWTLFCRKPLTvaelkyA 481
                 333........44444.3.33333333335555555555555555555555551 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.8   0.0   1.1e-08   2.1e-05       6     124 ..     210     344 ..     206     356 .. 0.84
   2 ?   -3.4   0.0       5.4   1.1e+04      43      70 ..     974    1001 ..     962    1016 .. 0.76

  Alignments for each domain:
  == domain 1  score: 24.8 bits;  conditional E-value: 1.1e-08
      AAA_22   6 gilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelka....................erlsseellealeq 84 
                 ++l+++G++G+GKT+l   + + l++    + +++ +vf+ + ++++ ++ +  ll+ +  +l +                    + +ss+++ +a++ 
  EEA21832.1 210 RSLYCIGPAGIGKTFLSSVIIDHLQR--TFTSPDVAIVFIFCHKEKDGENSCPVLLQSVLAQLIYrrralsqstealynfeaasgAKASSKAYQNAIRA 306
                 589********************953..333467777799999999888888888888888887788889999********9999999999999***** PP

      AAA_22  85 alraravielliiDEaqhlr.seealeeLrsllnlsrkgvq 124
                  +++ ++ ++l+iD  + ++ +++ l+   +l +  ++++ 
  EEA21832.1 307 EVNHFSK-VFLVIDGLDTISdRDRFLNRMQKLPE--HTQLL 344
                 ****999.***********655999999888887..66655 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 5.4
      AAA_22   43 vfvtlpsstsskdllrellralglelka 70  
                  ++v++ ss ++k + ++ ++ +g++  +
  EEA21832.1  974 LSVDALSSQGWKPIHQAAFKGTGSPDIT 1001
                  5788889999999999999999998887 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   4.2e-05     0.083       2     129 ..     213     381 ..     212     384 .. 0.68

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 4.2e-05
                 EEESSTTSSHHHHHHHHHHHHTHE.......EEEEETTTCSSS........................................STTHHHHHHHHHHHHH CS
         AAA   2 llyGppGtGKTllakavakelgve.......fleisgsellsk........................................yvgesekkirelfkea 53 
                 + +Gp G+GKT l + ++ +l+++       ++ i ++    k                                          ++s+k  ++ ++ a
  EEA21832.1 213 YCIGPAGIGKTFLSSVIIDHLQRTftspdvaIVFIFCH----KekdgenscpvllqsvlaqliyrrralsqstealynfeaasGAKASSKAYQNAIR-A 306
                 678*****************976533333333333333....1333456677777777777777888888888888888777666677777777764.4 PP

                 HHTS.TSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTSSSTEEEEEEESSGGGSTHHHHSTTSSEEEE CS
         AAA  54 keka.kpsilfiDEidalaksrsgseseeeervvnqLlteldgvkkkeskvivigatnrpdkldpallrgRfdrkie 129
                 + +  +++ l+iD +d +  +++  ++ ++     qLl  l + ++  +k+  i ++   +++++ ++  R+d+  +
  EEA21832.1 307 EVNHfSKVFLVIDGLDTISDRDRFLNRMQKLPEHTQLLITLRESSDT-DKINYINVSSPKKDIKDYVV-TRLDKDAK 381
                 55557789**********77773334445555566777777777664.55888888888888888888.78887665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1202 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       656  (0.0365888); expected 358.6 (0.02)
Passed bias filter:                      522  (0.0291148); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.93u 0.32s 00:00:01.25 Elapsed: 00:00:00.50
# Mc/sec: 7293.06
//
Query:       EEA21833.1  [L=336]
Description: autophagy protein Apg5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.1e-61  206.5   0.0      5e-61  206.2   0.0    1.1  1  APG5      Autophagy protein Apg5


Domain annotation for each model (and alignments):
>> APG5  Autophagy protein Apg5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  206.2   0.0   2.8e-65     5e-61       1     228 []      87     333 ..      87     333 .. 0.96

  Alignments for each domain:
  == domain 1  score: 206.2 bits;  conditional E-value: 2.8e-65
        APG5   1 WhlPiGvlyDlltaseeesksaasse........................aiseknlPwrLtlhfkeypenellpldageeslkdsfinslKeAdfirn 75 
                 Wh+P+G+lyDl++++e+ s+ +as+                         a+++++lPwrLtlhf+++p+++l++ldag   ++d+fins+KeAd +r 
  EEA21833.1  87 WHYPLGLLYDLYAGAEPISQASASDYndltqsvilaggkniqpigedegdASNSNRLPWRLTLHFDHWPDEDLVRLDAGGLVMHDAFINSVKEADSLRI 185
                 *****************9876554449**********************999999******************************************** PP

        APG5  76 gsakkvmnLskedqeqLWqsvknhdldkfwsinskllpspekkkvreiPiriylpdankdqtesekviqelvppl..........kedgqpqtLgdlls 164
                 ++ak +m+Lsked+ ++W +++nhdl+++ +i + llps+  +++r+iP+r++lp  +++++  +kv+q++v+p           +   qpqt+g++l+
  EEA21833.1 186 REAKGIMTLSKEDTAGFWAAIQNHDLSSYRRITNLLLPSSP-QPFRQIPLRVFLPLPPDSDRPALKVVQSPVSPFiqsssgtgtsAGRMQPQTVGSALH 283
                 ***************************************88.7***********99999999*****************99999888899********* PP

        APG5 165 ellpelfpskkkkekasssekeegsaaelakvliqGievpleaplawlaanlsypDgFlhivvv 228
                 +llp+lfps++ +  a              k++++G+++p++apl+++a+ ++y Dg+++iv++
  EEA21833.1 284 SLLPNLFPSRRIPVLA--------------KPILHGVVLPMSAPLEEVARSAVYGDGWVSIVIC 333
                 ********99998776..............9*******************************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (336 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       268  (0.0149478); expected 358.6 (0.02)
Passed bias filter:                      248  (0.0138323); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 2231.82
//
Query:       EEA21834.1  [L=332]
Description: hypothetical protein PMAA_056260 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        1.5    8.9   3.4       0.79    9.7   0.6    2.0  3  DUF4192   Domain of unknown function (DUF4192)


Domain annotation for each model (and alignments):
>> DUF4192  Domain of unknown function (DUF4192)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0     0.094   1.7e+03     144     191 ..      32      74 ..      28     102 .. 0.65
   2 ?    9.7   0.6   4.4e-05      0.79     173     252 ..     136     215 ..      89     226 .. 0.75
   3 ?   -3.7   0.0      0.52   9.3e+03     144     179 ..     276     310 ..     270     315 .. 0.62

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.094
     DUF4192 144 vegsReelearlapvega.aaraaqrraaeraaaaleralarprdaerr 191
                 ++ s +++ea+++pv+++ +        +  +a+ +er ++r++ + r+
  EEA21834.1  32 PRQSSTPIEALFTPVTPNcE------TSQTPIAPSIERSQLREASQLRN 74 
                 67788889999999977633......23345556666666655555554 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 4.4e-05
     DUF4192 173 raaaaleralarprdaerrsdpaevrraaleavraalarvaagaglsdaeeaarlavaLtdvrvRDaalalalgeeaaaa 252
                 +a+ ++++a +++ +  r+ +++   + a++++ + l+++ + ++ ++a++++++    ++v  RD +l+ ++++ ++ a
  EEA21834.1 136 EARVRAREAYTQKYETGRETEASTPLDVAIDEWIEFLQEYSEEEKEESAQKTQDILFQQQQVLYRDGLLETMEKAAKRRA 215
                 22222222222222333337789999*******************99999**********************96555544 PP

  == domain 3  score: -3.7 bits;  conditional E-value: 0.52
     DUF4192 144 vegsReelearlapvegaaaraaqrraaeraaaale 179
                 +  +R+ + ++++p    ++++a +++++ ++++++
  EEA21834.1 276 LKQDRRLIKSLITPSSN-KDHDALAQQVKNISKRVD 310
                 55677777777777544.445555665666666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (332 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1907  (0.106364); expected 358.6 (0.02)
Passed bias filter:                      597  (0.033298); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.42
# Mc/sec: 2377.76
//
Query:       EEA21835.1  [L=81]
Description: hypothetical protein PMAA_056270 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (81 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       482  (0.0268838); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.34u 0.24s 00:00:00.58 Elapsed: 00:00:00.37
# Mc/sec: 651.83
//
Query:       EEA21836.1  [L=408]
Description: alpha/beta hydrolase family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.7e-10   39.5   0.1    8.8e-10   38.2   0.1    1.6  1  Hydrolase_4    Serine aminopeptidase, S33
    1.1e-08   35.9   0.2    1.6e-08   35.4   0.2    1.4  1  Abhydrolase_6  Alpha/beta hydrolase family
    2.2e-08   34.1   3.4    3.2e-07   30.3   3.4    2.7  1  Abhydrolase_1  alpha/beta hydrolase fold
  ------ inclusion threshold ------
      0.074   12.7   0.4        2.1    7.9   0.0    2.3  2  FSH1           Serine hydrolase (FSH1)
      0.092   12.3   0.1          3    7.4   0.0    2.6  3  DLH            Dienelactone hydrolase family


Domain annotation for each model (and alignments):
>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.2   0.1   2.5e-13   8.8e-10       5     116 ..     104     218 ..     100     255 .. 0.83

  Alignments for each domain:
  == domain 1  score: 38.2 bits;  conditional E-value: 2.5e-13
  Hydrolase_4   5 avvvlvHGlaehsgryaelaeaLaaqGfavyalDhrGhGrsegkrghvpsfddyvdDlaafvekvk.eehpel...plfllGhSmGGliallyllryp 98 
                  + v+lvHG+   s     la+ L+++G  v+ +D  G G s    g++p+ d++ +    +v +     + ++   ++ l+G S+GG i+++++ + +
   EEA21836.1 104 HKVLLVHGISTPSVSLGGLAHSLVDRGCRVMLFDLFGRGFS-DTPGDIPQDDRLFATQILLVLTSSpLSWTGSssgKFSLIGYSLGGGITAAFASHFH 200
                  579**************************************.89999**999999888777744443556555678******************9999 PP

  Hydrolase_4  99 dkvaglilsaPalkikak 116
                  d ++ lil aPa  ++ +
   EEA21836.1 201 DLLSSLILLAPAGLMRDS 218
                  99**********877754 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.4   0.2   4.4e-12   1.6e-08       1     125 [.     106     247 ..     106     401 .. 0.64

  Alignments for each domain:
  == domain 1  score: 35.4 bits;  conditional E-value: 4.4e-12
                    EEEE--GC.....GCHHHH.HHHHCCTCEEEEE--TTSTS-GGCS--HHHCHHH.HHHHCCTT...........TTSEEEEEETCHHHHHHHHHHC CS
  Abhydrolase_6   1 vlllHGagssassWlvapL.aallaagvhvlapDlpGhGrsdpppldledladl.aalldelaa.........gggpvvlvGHSlGGalalaaapl 85 
                    vll+HG ++++ s   + L + l  +g++v  +Dl G G+sd+p +  +d ++l a ++  + +         + g++ l+G+SlGG + +a+a++
     EEA21836.1 106 VLLVHGISTPSVS--LGGLaHSLVDRGCRVMLFDLFGRGFSDTPGDIPQD-DRLfATQILLVLTssplswtgsSSGKFSLIGYSLGGGITAAFASH 198
                    89****7753222..235556666777************99888888877.4444444444444577789999*************9988885555 PP

                    C....EE.EEES-..........----TTTS----TTHHHHHHTT-CCCCH CS
  Abhydrolase_6  86 a..lvvg.vlldp........pptalpagllaaalelllallallrllawl 125
                       l+++ +ll+p           ++ ++ll+a   l++ ++++l++ +++
     EEA21836.1 199 FhdLLSSlILLAPaglmrdshV--GWQTRLLNAKGLLPESVISRLVKGRLR 247
                    57766669*****433333320..333333444444444443333333332 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.3   3.4   8.8e-11   3.2e-07       3     116 ..     106     225 ..     105     393 .. 0.71

  Alignments for each domain:
  == domain 1  score: 30.3 bits;  conditional E-value: 8.8e-11
                    EEEE-STTTCGGGGTTGHHHHHHHHTTSEEEEEEETTSTTSSSTTTGB...CHHSHHHHHHHHHHH.......HHHCTTSSEEEEEETHHHHHHHH CS
  Abhydrolase_1   3 lvilhGlpgssdvwaerglapaLakdgfdvillDlrGvgySspapacin..ddygtasvaddldri.......ldalgddkltlvGhSmGGmiala 89 
                    ++++hG+   s +  +  la  L ++g++v l+Dl G g+S+++ + ++      +  +a  +  +             +k+ l+G+S+GG i +a
     EEA21836.1 106 VLLVHGISTPSVSLGG--LAHSLVDRGCRVMLFDLFGRGFSDTPGDIPQddR---L--FATQILLVltssplsWTGSSSGKFSLIGYSLGGGITAA 194
                    7999999998877667..99999999********************988531...2..22222222111342355556678999************ PP

                    HHHHHGGGEEEEEEESE....CSSCCHHHHH CS
  Abhydrolase_1  90 yaaeyperVkalvllga....idpaasliea 116
                    +a+ + +  ++l+ll++     d++  +   
     EEA21836.1 195 FASHFHDLLSSLILLAPaglmRDSHVGWQTR 225
                    *****************77755555554444 PP

>> FSH1  Serine hydrolase (FSH1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.1     0.028     1e+02     105     128 ..     181     204 ..     174     224 .. 0.88
   2 ?    7.9   0.0   0.00059       2.1     163     206 ..     351     395 ..     334     399 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.028
        FSH1 105 GiiGFSqGaalaallaslleellk 128
                  +iG+S G+ ++a+ as ++ ll 
  EEA21836.1 181 SLIGYSLGGGITAAFASHFHDLLS 204
                 58****************998875 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.00059
        FSH1 163 ptLhvlGelDtvvdee.rseaLaeafknsskvlkHpggHfvPnkk 206
                 ++L vlGe D+v+ ++   e+  +a + ++++ +++ gH +P+ k
  EEA21836.1 351 KVLVVLGEIDNVIFKDdTVEDVTHALEGNAQITYFSIGHEFPSVK 395
                 79*********996552778888888888*************976 PP

>> DLH  Dienelactone hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.0   0.00083         3      95     120 ..     175     200 ..     107     209 .. 0.87
   2 ?   -1.8   0.0       0.5   1.8e+03     172     215 ..     293     337 ..     280     339 .. 0.84
   3 ?    1.8   0.0     0.041   1.5e+02     146     190 ..     351     392 ..     337     402 .. 0.79

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.00083
         DLH  95 vstkkvgvvGfCmGGalalllaaevp 120
                  s++k+ ++G+ +GG ++ ++a++  
  EEA21836.1 175 SSSGKFSLIGYSLGGGITAAFASHFH 200
                 45799*****************9983 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.5
         DLH 172 aanvdlelkvYpgagHaFandsre.syneeaaedawervlelfkq 215
                 a+ v+ +++ ++g   aF    r+    ++++ + w+r+ +++ q
  EEA21836.1 293 AEAVAWQVENHDGFIPAFISSMRHgPILQKSQLENWKRLGSFLSQ 337
                 566788999999999999998888788899999999999999876 PP

  == domain 3  score: 1.8 bits;  conditional E-value: 0.041
         DLH 146 pilalfgeeDefipadevekleealkaanvdlelkvYpgagHaFa 190
                  +l+++ge D++i +d+  ++e  + a + ++++  ++  gH F 
  EEA21836.1 351 KVLVVLGEIDNVIFKDD--TVEDVTHALEGNAQITYFS-IGHEFP 392
                 58999******999885..5555555557888999998.899885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (408 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       428  (0.0238719); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.55u 0.31s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 2640.46
//
Query:       EEA21837.1  [L=1421]
Description: ABC multidrug transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.5e-55  187.6  42.1    5.4e-36  124.7  20.3    3.2  3  ABC_membrane    ABC transporter transmembrane region
    2.8e-50  170.4   0.2    1.2e-28  100.3   0.3    2.8  2  ABC_tran        ABC transporter
    2.7e-06   26.8   0.1     0.0015   17.9   0.0    2.6  2  Zeta_toxin      Zeta toxin
    1.2e-05   25.3   0.7      0.022   14.8   0.2    2.9  2  MMR_HSR1        50S ribosome-binding GTPase
    6.9e-05   22.4   4.6       0.68    9.3   1.7    3.6  2  SMC_N           RecF/RecN/SMC N terminal domain
    7.7e-05   23.1   1.3       0.62   10.4   1.0    3.1  2  AAA_16          AAA ATPase domain
    0.00029   20.5   1.9       0.55   10.0   0.1    2.6  2  AAA_29          P-loop containing region of AAA domain
     0.0005   20.0   4.7       0.71    9.6   0.3    3.6  3  AAA_21          AAA domain, putative AbiEii toxin, Type IV TA
     0.0022   17.9   2.2       0.74    9.7   0.1    2.6  2  RsgA_GTPase     RsgA GTPase
     0.0044   17.1   4.3       0.24   11.4   0.3    3.1  2  Dynamin_N       Dynamin family
  ------ inclusion threshold ------
      0.011   15.9   2.2       0.31   11.1   0.3    2.5  2  DUF87           Helicase HerA, central domain
      0.015   15.8   0.1        3.3    8.2   0.0    3.1  3  AAA_18          AAA domain
      0.032   14.5   4.8          2    8.7   0.1    3.5  2  AAA_22          AAA domain
      0.071   12.0   1.4        1.3    7.8   0.0    2.3  2  TrwB_AAD_bind   Type IV secretion-system coupling protein DNA
      0.079   12.7   5.1        2.4    7.8   0.3    2.5  2  AAA_15          AAA ATPase domain
      0.088   13.0   0.3         18    5.6   0.0    2.7  2  Roc             Ras of Complex, Roc, domain of DAPkinase
        0.1   13.1  11.1        1.2    9.6   2.7    3.5  3  AAA_23          AAA domain
       0.15   12.0   1.3         13    5.7   0.1    2.6  2  Ploopntkinase3  P-loop Nucleotide Kinase3
       0.16   12.4   0.4        8.6    6.8   0.0    3.0  2  AAA             ATPase family associated with various cellula
       0.23   11.1   4.8        4.6    6.9   0.2    2.9  3  AAA_30          AAA domain
       0.73    8.1  10.1     0.0062   14.9   1.3    1.9  2  CDC45           CDC45-like protein
        1.9    8.2   6.0         13    5.5   0.1    2.8  3  ATP_bind_1      Conserved hypothetical ATP binding protein


Domain annotation for each model (and alignments):
>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.7   0.6   0.00018      0.15       2      89 ..     171     266 ..     170     275 .. 0.86
   2 !   61.7   6.9     1e-19   8.2e-17      96     273 ..     296     470 ..     289     471 .. 0.95
   3 !  124.7  20.3   6.6e-39   5.4e-36       2     268 ..     839    1097 ..     838    1103 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00018
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSS...TCCHH........HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCS CS
  ABC_membrane   2 iliillailagvlsplfplvlgrildtlldk...gdpet........ealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrq 87 
                   +l+ ++ +++ +  ++ p+ + +++   ++    +            ++ + +++ ++++ ++q++++    y    +g +l+  l + +f+k ++ 
    EEA21837.1 171 WLGGVCNFFNSLFTVFSPYMTRYLIAYATEAytaK---AnnqpepkiAHGIGFAVGITVMQICQSLCTNQFIYRGFLVGAQLRAVLINVIFDKTMKI 264
                   67889999999999999999988888888865441...2444578**************************************************98 PP

                   TH CS
  ABC_membrane  88 pm 89 
                   + 
    EEA21837.1 265 SN 266
                   76 PP

  == domain 2  score: 61.7 bits;  conditional E-value: 1e-19
                   CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHH CS
  ABC_membrane  96 svGellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirt 192
                   s G+++++++ d++++++++g+++++++ +l+++++++++++ +g + +l ++a+l+l i++  ++ k l k ++  ++ ++++ s+++E+l+ +r 
    EEA21837.1 296 SNGRIITLMSVDADRINTAMGMFHLMWSSPLILILAVILLCVNIGYS-ALSGFALLLLGIPSLTLVIKSLLKRRDYINNLTDQRVSLTQEILQSVRF 391
                   68********************************************8.9************************************************ PP

                   HHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSTHHHHHHHHHHHHHHHHH CS
  ABC_membrane 193 VkafgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttlvisgelsvgdlvvflslfailfga 273
                   Vk fg+e+ f  + +  ++++ +a    + +++++  ++ ++++++ +l +   t+  +++ l++  ++  l+lf+ l  +
    EEA21837.1 392 VKFFGWESSFMARLKGIRKQEIRAIQVLLAIRNAILCVSLAMPTFASMLSFI--TYSLSQHVLTPAPIFSSLALFNSLRVP 470
                   ********************************************99999955..7777789******99999999988766 PP

  == domain 3  score: 124.7 bits;  conditional E-value: 6.6e-39
                    HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHHHHSC CS
  ABC_membrane    2 iliillailagvlsplfplvlgrildtlldkgdpetealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsffdtns 96  
                    i+++++++l+ + +++++++l+++++      +     + +y+  +++l+++q+++++++s++l+v+g ++sk + +k++ ++lr+pmsffdt++
    EEA21837.1  839 IFVVVSIVLTNASNIMTSFWLAYWTSGQYN-LT-----TGQYIAGYASLAVLQAVIMFIYSTVLSVAGTNASKNMLQKAMTRVLRAPMSFFDTTP 927 
                    6789999*****************998765.33.....456****************************************************** PP

                    HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHH CS
  ABC_membrane   97 vGellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgir 191 
                     G++++r+++dv+ +++ lg+ + +   +++t+v+++i+++++  +++++  ++++l+++ + ++    +++k+ e+  ++ ++s + Es+sg+ 
    EEA21837.1  928 LGRITNRFSKDVHVMDNELGDAMRIYGLNITTIVAIIILIIVYFHYFAIAFGPLMILFLVAANYYRASARDMKRFESVLRSHVFSRFSESISGVA 1022
                    *********************************************************************************************** PP

                    HHHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT.TSSTHHHHHHHHHHHH CS
  ABC_membrane  192 tVkafgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttlvis.gelsvgdlvvflslfa 268 
                     ++a+g +++f + + +a++e+ +a++     +++l+++++++g+++++++   G+  v s  ++s++    +ls++ 
    EEA21837.1 1023 SIRAYGLQDQFSRSISDAIDEMDSAYFLTFSNQRWLSVRLDAVGYVMVFVT---GILVVTSrFNVSPSISGLVLSYIL 1097
                    **********************************************99999...666666634666666557777766 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.2   0.0   2.6e-21   2.1e-18       2     136 ..     563     696 ..     562     697 .. 0.90
   2 !  100.3   0.3   1.5e-31   1.2e-28       1     137 []    1168    1337 ..    1168    1337 .. 0.91

  Alignments for each domain:
  == domain 1  score: 67.2 bits;  conditional E-value: 2.6e-21
                 EEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH......HHHTCHHHHHHHSTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxx RF
    ABC_tran   2 knvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren......esdeeiekalsklgl 94 
                 +++sl++k++e++a++G  G+GK++Ll++lag ++ teG+i             +l ++ +++pq + +++ + vren      +++++ +++++   l
  EEA21837.1 563 SDISLSVKRNELIAVIGTVGSGKTSLLAALAGDMRLTEGSI-------------KLGASRAYCPQYAWIQNAT-VRENisfakkYDESWYNTVVDACAL 647
                 689**************************************.............7899999*****8888887.****999998777777777777777 PP

                 GG.......TTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 xx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  95 ke.......lkdtvvksspssLSgGqkqrvalarallkkpkllllDEpt 136
                           + t +++++ ++SgGqkqr+ +ara+  +++++l+D+p 
  EEA21837.1 648 RPdfdvfpnGDSTEIGERGITVSGGQKQRLNIARAIYFNSDIILMDDPL 696
                 7777777777788999999****************************97 PP

  == domain 2  score: 100.3 bits;  conditional E-value: 1.5e-31
                  EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.................. CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.................. RF
    ABC_tran    1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren.................. 79  
                  l+ ++++++ ge+++ivG++GaGKS+++++l + ++   G+i++dgkd+ +  l+ lr++++++pq+p+lf+++ +r+n                  
  EEA21837.1 1168 LRGLNMDIRGGERIGIVGRTGAGKSSIMSALFRITELSGGSITIDGKDIGKVGLQDLRSRLAIIPQDPTLFRGT-IRSNldpfnehddlelwdalrk 1263
                  57899*********************************************************************.**********999999999999 PP

                  .................HHHTCHHHHHHHSTTGGTTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                  .................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran   80 .................esdeeiekalsklglkelkdtvvksspssLSgGqkqrvalarallkkpkllllDEpta 137 
                                   e++ + +k  ++ + ++  d++v++++ ++S Gq+q +alaral+++++++++DE+t+
  EEA21837.1 1264 shligeqpegseleesdEEKTQQQKQTQHSNRIQ-LDSTVDEEGLNFSLGQRQLMALARALVRNSRIIICDEATS 1337
                  9999999999999976644444555555555555.688889********************************96 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.0   1.8e-06    0.0015      12      90 ..     568     644 ..     560     648 .. 0.88
   2 !    5.8   0.2    0.0088       7.2      21      53 ..    1183    1215 ..    1180    1218 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 1.8e-06
  Zeta_toxin  12 sqerPklillgGqpGAGKselaellkdelerqgnvvrldpDdlRelhPeyeeilkadpkkaseltqkdaselvekllqe 90 
                 s +r  li + G  G+GK++l+++l+ +++ +++ ++l +   R++ P+y+ i++a ++++ + ++k    + ++++++
  EEA21837.1 568 SVKRNELIAVIGTVGSGKTSLLAALAGDMRLTEGSIKLGA--SRAYCPQYAWIQNATVRENISFAKKYDESWYNTVVDA 644
                 56788899999******************99999998886..69*******************9999999999888775 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0088
  Zeta_toxin   21 lgGqpGAGKselaellkdelerqgnvvrldpDd 53  
                  ++G +GAGKs+++++l + +e  g+ +++d+ d
  EEA21837.1 1183 IVGRTGAGKSSIMSALFRITELSGGSITIDGKD 1215
                  789************999888899999999765 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.9   0.0    0.0039       3.2       2      22 ..     575     595 ..     574     615 .. 0.85
   2 !   14.8   0.2   2.7e-05     0.022       1      21 [.    1180    1200 ..    1180    1218 .. 0.88

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0039
                 EEEEESTTSSHHHHHHHHHTS CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltge 22 
                 +a++G   +GK++L+ al g+
  EEA21837.1 575 IAVIGTVGSGKTSLLAALAGD 595
                 89****************996 PP

  == domain 2  score: 14.8 bits;  conditional E-value: 2.7e-05
                  EEEEEESTTSSHHHHHHHHHT CS
    MMR_HSR1    1 evaivGrpNvGKStLinaltg 21  
                  +++ivGr+ +GKS++++al++
  EEA21837.1 1180 RIGIVGRTGAGKSSIMSALFR 1200
                  69*****************86 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.3   0.1    0.0071       5.8      25      44 ..     573     592 ..     560     602 .. 0.87
   2 !    9.3   1.7   0.00083      0.68      29     208 ..    1183    1376 ..    1176    1384 .. 0.55

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0071
                 SEEEEEESTTSSHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxx RF
       SMC_N  25 sftaivGpNGSGKsnlldAi 44 
                 ++ a++G  GSGK++ll A+
  EEA21837.1 573 ELIAVIGTVGSGKTSLLAAL 592
                 5789**************98 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.00083
                  EEESTTSSHHHHHHHHHHHCTT.TT.......TTTTCHCCCCCC--...BTTCSSTTEEEEEEEEEETTEESSSSSSCEEEEEEEETTSEEEEEETT CS
                  xxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N   29 ivGpNGSGKsnlldAilFvLGersa.......kklrseklsdlihk...skekasvkkaeveitfdnedkklkiekeevsisrrvkrkgeseyking 115 
                  ivG+ G+GKs+++ A+ F + e s        k + +  l+dl ++     + + + ++++   +d  +++                          
  EEA21837.1 1183 IVGRTGAGKSSIMSAL-FRITELSGgsitidgKDIGKVGLQDLRSRlaiIPQDPTLFRGTIRSNLDPFNEH-------------------------- 1252
                  6777777777777776.665544321111111333333444444334443445555555555554333333.......................... PP

                  EEE-HHHHHHHHHCTT-STT......................................................CS-HHHHHHHHHHHHHHHHCCS- CS
                  xxxxxxxxxxxxxxxxxxxx......................................................xxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  116 kevtkkevsellesagiske......................................................lLSgGektLvalaLlfAiqkvkp 158 
                                     +                                                      ++S G+++L+ala       v+ 
  EEA21837.1 1253 -------------------DdlelwdalrkshligeqpegseleesdeektqqqkqtqhsnriqldstvdeeglNFSLGQRQLMALARA----LVRN 1326
                  ...................0222222222222222222222222223333333333333333333355777888899999999887654....4677 PP

                  -SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC-SCE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  159 aplyllDeidaaLDeknvkkvaellkeksknaQfivislreemlekadkl 208 
                  + + + De  +  D++  +k+ + + +  k   +++i++r +++   d++
  EEA21837.1 1327 SRIIICDEATSSVDFETDRKIQRTMATGFKGKTLLCIAHRLRTIITYDRI 1376
                  78888999999999999999999999999999999999998888777766 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.0    0.0017       1.4      25      63 ..     573     615 ..     565     651 .. 0.73
   2 !   10.4   1.0   0.00076      0.62      25     143 ..    1179    1334 ..    1166    1353 .. 0.62

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.0017
      AAA_16  25 elvllsGesGvGKsslvrellralekd....ggiflrgkcdql 63 
                 el+ ++G  G+GK+sl+ +l+  ++ +    +  + r+ c q+
  EEA21837.1 573 ELIAVIGTVGSGKTSLLAALAGDMRLTegsiKLGASRAYCPQY 615
                 7999*************99997555443333222245555544 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00076
      AAA_16   25 elvllsGesGvGKsslvrellralekd.............................ggif...lrgkcdqlesaipy.....salaqalareellrq 84  
                  e + ++G  G GKss++ +l+r  e +                               +f   +r + d       +     + l++al +++l+ +
  EEA21837.1 1179 ERIGIVGRTGAGKSSIMSALFRITELSggsitidgkdigkvglqdlrsrlaiipqdPTLFrgtIRSNLDP------FnehddLELWDALRKSHLIGE 1269
                  556699***************7444446666666777777777766665555555312222224444444......244443448999999999999 PP

      AAA_16   85 lldeaesaeleawrekleeala.....avpelagaea...........srllellkrllallsrderplvlvlDd 143 
                    + +e  e ++ +++ +++++     + ++                 +r l +l+r+l++ s      ++++D+
  EEA21837.1 1270 QPEGSELEESDEEKTQQQKQTQhsnriQLDS-----TvdeeglnfslgQRQLMALARALVRNS-----RIIICDE 1334
                  8888777777777777777777555552222.....233334555455555555555554444.....3777776 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   0.2    0.0013         1      17      42 ..     567     592 ..     560     594 .. 0.81
   2 !   10.0   0.1   0.00068      0.55      19      42 ..    1175    1198 ..    1168    1202 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0013
      AAA_29  17 ieidlkgatlltGpsGsGKSTllDAi 42 
                 +++++++ + ++G+ GsGK++ll A+
  EEA21837.1 567 LSVKRNELIAVIGTVGSGKTSLLAAL 592
                 56677778999***********9876 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00068
      AAA_29   19 idlkg..atlltGpsGsGKSTllDAi 42  
                  i+  g   + ++G++G+GKS+++ A+
  EEA21837.1 1175 IR--GgeRIGIVGRTGAGKSSIMSAL 1198
                  44..3357789***********9887 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.7   0.7    0.0033       2.7       2      20 ..     575     593 ..     574     604 .. 0.90
   2 ?    1.6   0.0      0.25     2e+02     220     302 ..     650     731 ..     604     732 .. 0.76
   3 !    9.6   0.3   0.00087      0.71       3      42 ..    1182    1221 ..    1181    1255 .. 0.73

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0033
      AAA_21   2 nvliGpNgsGKSnLLdald 20 
                  ++iG  gsGK++LL al 
  EEA21837.1 575 IAVIGTVGSGKTSLLAALA 593
                 689**************95 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.25
      AAA_21 220 gvvflengdgqelparel..SdGtkrllalltallralkkgsllliDEpEngLHPkllrrll.ell.kelsrngaQv.iltTHSplll 302
                 ++  + ngd  e+  r +  S G+k+ l ++ a++      +++l D+p +  + ++ r+++ + +  +l++   ++ il+TH+ ++l
  EEA21837.1 650 DFDVFPNGDSTEIGERGItvSGGQKQRLNIARAIYFNS---DIILMDDPLSAVDAHVGRHIMdQAIcGLLKD---KCrILATHQLHVL 731
                 55556666666666666666999999999999999988...9********************9777755555...6669999999987 PP

  == domain 3  score: 9.6 bits;  conditional E-value: 0.00087
      AAA_21    3 vliGpNgsGKSnLLdaldllarldrdvegltdelsggggi 42  
                  +++G+ g+GKS+++ al  +  l + ++    ++ g++g+
  EEA21837.1 1182 GIVGRTGAGKSSIMSALFRITELSGGSITIDGKDIGKVGL 1221
                  69***************77765544444444444444444 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   0.1   0.00091      0.74      97     131 ..     569     604 ..     557     609 .. 0.82
   2 !    7.1   0.2    0.0059       4.8     100     127 ..    1179    1206 ..    1167    1217 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00091
                  CTT.SEEEEECSTTSSHHHHHHHHCTT-----S--- CS
  RsgA_GTPase  97 lkd.ktsvlvGqSGvGKStLinallpelelktgevs 131
                  +k  ++++++G  G GK++L+ al+++++l  g+++
   EEA21837.1 569 VKRnELIAVIGTVGSGKTSLLAALAGDMRLTEGSIK 604
                  44448999*******************999888775 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0059
                   SEEEEECSTTSSHHHHHHHHCTT----- CS
  RsgA_GTPase  100 ktsvlvGqSGvGKStLinallpelelkt 127 
                   + + +vG +G+GKS+++ al   +el+ 
   EEA21837.1 1179 ERIGIVGRTGAGKSSIMSALFRITELSG 1206
                   556799***********99987666655 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.4   0.3    0.0003      0.24       1      27 [.     575     601 ..     575     608 .. 0.88
   2 ?    5.8   0.5     0.016        13       1      20 [.    1181    1200 ..    1181    1297 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.0003
                 EEEEEBTTTTHHHHHHHHHTS--S--- CS
   Dynamin_N   1 iavvGsqSsGKSSvlnaLlgedilprg 27 
                 iav+G++ sGK+S+l aL g+  l  g
  EEA21837.1 575 IAVIGTVGSGKTSLLAALAGDMRLTEG 601
                 89******************8766655 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.016
                  EEEEEBTTTTHHHHHHHHHT CS
   Dynamin_N    1 iavvGsqSsGKSSvlnaLlg 20  
                  i +vG + +GKSS++ aL +
  EEA21837.1 1181 IGIVGRTGAGKSSIMSALFR 1200
                  789************99976 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.1     0.074        60      19      43 ..     572     592 ..     559     600 .. 0.79
   2 ?   11.1   0.3   0.00038      0.31      24      45 ..    1179    1200 ..    1171    1211 .. 0.89

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.074
       DUF87  19 nklvtrHlAilgsTGsGKSntvavL 43 
                 n+l    +A++g+ GsGK+ + a L
  EEA21837.1 572 NEL----IAVIGTVGSGKTSLLAAL 592
                 444....8***********999987 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00038
       DUF87   24 rHlAilgsTGsGKSntvavLle 45  
                  ++++i+g+TG+GKS  ++ L++
  EEA21837.1 1179 ERIGIVGRTGAGKSSIMSALFR 1200
                  579**************99975 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   0.0    0.0041       3.3       1      19 [.     575     593 ..     575     637 .. 0.85
   2 ?   -2.5   0.0       8.9   7.3e+03     101     112 ..     755     766 ..     683     787 .. 0.56
   3 ?    4.1   0.0      0.08        65       1      22 [.    1181    1202 ..    1181    1305 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0041
      AAA_18   1 IlltGtpGvGKttlakeLs 19 
                 I++ Gt G+GKt+l  +L+
  EEA21837.1 575 IAVIGTVGSGKTSLLAALA 593
                 89************99996 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 8.9
      AAA_18 101 aspeelleRlek 112
                 +++++l++Rl  
  EEA21837.1 755 TRDNVLFQRLIS 766
                 345556666544 PP

  == domain 3  score: 4.1 bits;  conditional E-value: 0.08
      AAA_18    1 IlltGtpGvGKttlakeLskrl 22  
                  I++ G  G+GK+++  +L + +
  EEA21837.1 1181 IGIVGRTGAGKSSIMSALFRIT 1202
                  899************9995544 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.1    0.0025         2       5      26 ..     572     593 ..     568     604 .. 0.89
   2 ?    4.0   1.5     0.071        58      10      30 ..    1183    1203 ..    1175    1371 .. 0.61

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0025
      AAA_22   5 agilvvtGesGtGKTtllrrll 26 
                   +++v+G +G+GKT ll+ l+
  EEA21837.1 572 NELIAVIGTVGSGKTSLLAALA 593
                 6789*************99875 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.071
      AAA_22   10 vtGesGtGKTtllrrlleqld 30  
                  ++G +G+GK+  +  l++  +
  EEA21837.1 1183 IVGRTGAGKSSIMSALFRITE 1203
                  899999999999999987653 PP

>> TrwB_AAD_bind  Type IV secretion-system coupling protein DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   0.0    0.0016       1.3       3      40 ..     561     597 ..     559     603 .. 0.80
   2 ?    2.6   0.3     0.063        51      17      38 ..    1180    1201 ..    1168    1213 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0016
  TrwB_AAD_bind   3 siagvplpkeretqhilivGttGsGKtqalekllrair 40 
                    +i  ++l+++r +  i+++Gt+GsGKt  l +l   +r
     EEA21837.1 561 KISDISLSVKRNE-LIAVIGTVGSGKTSLLAALAGDMR 597
                    6777888877765.58999***********99976666 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.063
  TrwB_AAD_bind   17 hilivGttGsGKtqalekllra 38  
                      i ivG tG+GK+  +++l r 
     EEA21837.1 1180 RIGIVGRTGAGKSSIMSALFRI 1201
                     689**************99875 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   0.3    0.0029       2.4      14      43 ..     562     592 ..     561     594 .. 0.86
   2 ?    6.7   0.0    0.0063       5.1      28      84 ..    1183    1273 ..    1178    1336 .. 0.66

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0029
      AAA_15  14 lkdveidlsee.ltvliGkNnsGKSsileal 43 
                 ++d++++++ + l  +iG+ +sGK+s+l al
  EEA21837.1 562 ISDISLSVKRNeLIAVIGTVGSGKTSLLAAL 592
                 567777777778*****************98 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0063
      AAA_15   28 liGkNnsGKSsilealdlFlnnkekknkkvikiekedleifeniseskdikIdvef......................................a 84  
                  ++G+ ++GKSsi+ al  + + +       i+i+ +d+ +   ++   ++ I  +                                        
  EEA21837.1 1183 IVGRTGAGKSSIMSALFRITELS----GGSITIDGKDIGKVGLQDLRSRLAIIPQDptlfrgtirsnldpfnehddlelwdalrkshligeqpeG 1273
                  89**************6666655....66777888887777777777777777777777777777766666666666555555544444333220 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0     0.022        18       2      28 ..     575     601 ..     574     629 .. 0.78
   2 ?    4.5   0.2     0.048        39       2      20 ..    1181    1199 ..    1180    1218 .. 0.85

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.022
                 EEEESSTTSSHHHHHHCHCT-CCC-EE CS
         Roc   2 vvlvGdsgvGKtsllkrfvedkfseke 28 
                 + ++G  g+GKtsll  +  d   ++ 
  EEA21837.1 575 IAVIGTVGSGKTSLLAALAGDMRLTEG 601
                 679************999887665555 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.048
                  EEEESSTTSSHHHHHHCHC CS
         Roc    2 vvlvGdsgvGKtsllkrfv 20  
                  + +vG +g+GK+s+++ + 
  EEA21837.1 1181 IGIVGRTGAGKSSIMSALF 1199
                  779************9876 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   0.1     0.017        14      18      39 ..     571     592 ..     556     594 .. 0.79
   2 ?   -0.1   0.2       1.4   1.1e+03      81     138 ..     753     811 ..     724     828 .. 0.56
   3 ?    9.6   2.7    0.0014       1.2      24      42 ..    1183    1201 ..    1180    1348 .. 0.76

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.017
      AAA_23  18 skgltlItGpNGaGKTTildAi 39 
                  + l +++G  G+GKT++l A+
  EEA21837.1 571 RNELIAVIGTVGSGKTSLLAAL 592
                 56789999*************8 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 1.4
      AAA_23  81 nkdgrytrsiererelskkkgkttkkaklelleideleqfise....llgskkiilnlilfl 138
                 n ++   +++ ++r  s +  ++ +++++ + e+d+  ++i++      +++k+  +  l++
  EEA21837.1 753 NLTR---DNVLFQRLISTTTQDQENDKEKGEEEDDDEADKIDKeevvPAKKTKRGKQAALMQ 811
                 3333...3344555555555555544444444444445555544322222222233333333 PP

  == domain 3  score: 9.6 bits;  conditional E-value: 0.0014
      AAA_23   24 ItGpNGaGKTTildAikla 42  
                  I+G +GaGK++i+ A+  +
  EEA21837.1 1183 IVGRTGAGKSSIMSALFRI 1201
                  9**************9765 PP

>> Ploopntkinase3  P-loop Nucleotide Kinase3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0     0.038        31       4      25 ..     573     594 ..     570     608 .. 0.86
   2 ?    5.7   0.1     0.016        13       6      25 ..    1181    1200 ..    1178    1219 .. 0.87

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.038
  Ploopntkinase3   4 rliylvGqPGaGkstlmaeltk 25 
                      li ++G+ G+Gk+ l+a+l+ 
      EEA21837.1 573 ELIAVIGTVGSGKTSLLAALAG 594
                     6999***************975 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.016
  Ploopntkinase3    6 iylvGqPGaGkstlmaeltk 25  
                      i +vG  GaGks +m++l +
      EEA21837.1 1181 IGIVGRTGAGKSSIMSALFR 1200
                      569*************9966 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.0     0.011       8.6       3      25 ..     577     599 ..     575     637 .. 0.73
   2 ?    2.2   0.0      0.29   2.3e+02       3      35 ..    1183    1217 ..    1181    1236 .. 0.71

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.011
                 EESSTTSSHHHHHHHHHHHHTHE CS
         AAA   3 lyGppGtGKTllakavakelgve 25 
                 ++G+ G GKT+l  a+a ++  +
  EEA21837.1 577 VIGTVGSGKTSLLAALAGDMRLT 599
                 79****************98644 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.29
                  EESSTTSSHHHHHHHHHHHH..THEEEEEETTTCS CS
         AAA    3 lyGppGtGKTllakavakel..gvefleisgsell 35  
                  ++G  G GK+++++a+ + +  +   ++i+g+++ 
  EEA21837.1 1183 IVGRTGAGKSSIMSALFRITelSGGSITIDGKDIG 1217
                  6899************9875114556777777776 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.1     0.022        18      17      42 ..     571     596 ..     566     611 .. 0.77
   2 ?    6.9   0.2    0.0056       4.6      22      49 ..    1182    1209 ..    1175    1214 .. 0.86
   3 ?   -3.0   0.0       6.2     5e+03      81      98 ..    1315    1336 ..    1282    1354 .. 0.62

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.022
      AAA_30  17 gdrvavltGpAGtGKttalkalreaw 42 
                 ++ + ++ G  G+GKt +l+al+  +
  EEA21837.1 571 RNELIAVIGTVGSGKTSLLAALAGDM 596
                 5568899*************998655 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0056
      AAA_30   22 vltGpAGtGKttalkalreaweaaggrv 49  
                   ++G+ G+GK+ +++al ++ e +gg++
  EEA21837.1 1182 GIVGRTGAGKSSIMSALFRITELSGGSI 1209
                  589**************99999888766 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 6.2
      AAA_30   81 k....grarlepgtllivDEag 98  
                  +    +ra +++++++i DEa 
  EEA21837.1 1315 QlmalARALVRNSRIIICDEAT 1336
                  1334433455566777777774 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   1.3   7.6e-06    0.0062     101     171 ..     734     807 ..     701     822 .. 0.61
   2 ?   -4.3   2.0         5   4.1e+03     152     167 ..    1277    1291 ..    1250    1315 .. 0.47

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 7.6e-06
       CDC45 101 kerivvfDDgdi.....eeeleeereayealeeeeesdeedeeeeeeddddeeeeeeeeedeedeeedeeeskkkr 171
                  +rivv+DDg+i      e+l++++  +++l +   +d+e+++e+ e++dd+e  ++  ++ee   +++++++k+ 
  EEA21837.1 734 CDRIVVMDDGRInavdtFENLTRDNVLFQRLISTTTQDQENDKEKGEEEDDDE-ADKI-DKEEVVPAKKTKRGKQA 807
                 589********866555677777777888888888877555433333332222.2222.22222222222222222 PP

  == domain 2  score: -4.3 bits;  conditional E-value: 5
       CDC45  152 eeeedeedeeedeees 167 
                  ee+++e++++++ +++
  EEA21837.1 1277 EESDEEKTQQQK-QTQ 1291
                  111111111111.111 PP

>> ATP_bind_1  Conserved hypothetical ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.1       9.2   7.5e+03      47      65 ..     491     509 ..     489     510 .. 0.88
   2 ?    5.5   0.1     0.015        13       1      18 [.     577     594 ..     577     605 .. 0.84
   3 ?    5.3   0.2     0.018        15       1      26 [.    1183    1208 ..    1183    1211 .. 0.89

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 9.2
  ATP_bind_1  47 irelitledvmedlglgpn 65 
                 i+e++ +e+vmed +  +n
  EEA21837.1 491 IEEFLLEEEVMEDIKWDDN 509
                 89***********988777 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.015
  ATP_bind_1   1 vvGpaGsGKttfvgalse 18 
                 v+G++GsGKt++  al+ 
  EEA21837.1 577 VIGTVGSGKTSLLAALAG 594
                 89**********999875 PP

  == domain 3  score: 5.3 bits;  conditional E-value: 0.018
  ATP_bind_1    1 vvGpaGsGKttfvgalseilelrgrs 26  
                  +vG  G+GK+++++al  i+el+g s
  EEA21837.1 1183 IVGRTGAGKSSIMSALFRITELSGGS 1208
                  79******************998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1421 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1157  (0.0645323); expected 358.6 (0.02)
Passed bias filter:                      570  (0.0317921); expected 358.6 (0.02)
Passed Vit filter:                        90  (0.0050198); expected 17.9 (0.001)
Passed Fwd filter:                        26  (0.00145016); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              22  [number of targets reported over threshold]
# CPU time: 1.10u 0.34s 00:00:01.44 Elapsed: 00:00:00.53
# Mc/sec: 8043.20
//
Query:       EEA21838.1  [L=173]
Description: hypothetical protein PMAA_056300 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-18   67.1   0.0    4.9e-18   65.1   0.0    1.8  1  SnoaL     SnoaL-like polyketide cyclase
    5.9e-13   49.3   0.1    8.5e-13   48.8   0.1    1.2  1  SnoaL_2   SnoaL-like domain


Domain annotation for each model (and alignments):
>> SnoaL  SnoaL-like polyketide cyclase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.1   0.0   5.4e-22   4.9e-18       2     123 ..      28     142 ..      27     145 .. 0.95

  Alignments for each domain:
  == domain 1  score: 65.1 bits;  conditional E-value: 5.4e-22
                 HHHHHHHHHHHTT-HHHHHGTEEEEEEETCCTTTCECHHHHHHHHHHHHHHHCTTCEEEEEEEEEETTEEEEEEEEEEEES.SEBTTBE-TT-EEEEEE CS
       SnoaL   2 lvlrfyeevwnsgdldaldelvaedvvdhnpeeeparGlegfrafveelfkafPDlkvevedlvaegdkvaarltftGtht.geflGipptGkkvkfee 99 
                 l++rfy+++w+++d++ +  l++ ++ ++ +    ++G ++f+a v +l   +        dlv+egdkv a+l+f G h+ g ++G+p tG+ v + +
  EEA21838.1  28 LIRRFYKDLWDKQDTSLIPALIHSNFQFRGSLGPALTGHAEFAAYVHWLTGIL--------DLVEEGDKVTAKLRFHGIHRnGSLFGQPSTGRWVWWDG 118
                 689**************************999999***********9997655........9******************99***************** PP

                 EEEEEEETTEEEEEEEEECHHHHH CS
       SnoaL 100 itllrvedGkIveewdviDllgll 123
                 + ++++ed+kI + w + D +gl+
  EEA21838.1 119 VAIFTFEDDKINDLWVLGDVYGLM 142
                 **********************98 PP

>> SnoaL_2  SnoaL-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.8   0.1   9.5e-17   8.5e-13       1      99 [.      29     129 ..      29     132 .. 0.93

  Alignments for each domain:
  == domain 1  score: 48.8 bits;  conditional E-value: 9.5e-17
                 HHHHHH.HHHTTCHHHHHHTEEEEEEEEETTSE.EESHHHHHHHHHHHHHHEEEEEEEEEEEEEETTEEEEEEEEEEE........EETTSSEEEEEEE CS
     SnoaL_2   1 vrafla.alnagdldalaalfapdvvwedpgge.lrGreairaffralfaafpdlrfeihdvvadgdrvavewtvtgt........ipatgrgvtvrgv 89 
                 +r+f+   ++++d + + al + ++ +++ +g+ l+G+++++a++ +l          i d+v++gd+v +  +++g          p tgr v+++gv
  EEA21838.1  29 IRRFYKdLWDKQDTSLIPALIHSNFQFRGSLGPaLTGHAEFAAYVHWL--------TGILDLVEEGDKVTAKLRFHGIhrngslfgQPSTGRWVWWDGV 119
                 58999669**********************6666**********7777........57**************99999999******************* PP

                 EEEEEETTEE CS
     SnoaL_2  90 dvfrvrdGki 99 
                 ++f+++d+ki
  EEA21838.1 120 AIFTFEDDKI 129
                 *********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (173 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       260  (0.0145016); expected 358.6 (0.02)
Passed bias filter:                      248  (0.0138323); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.41u 0.28s 00:00:00.69 Elapsed: 00:00:00.43
# Mc/sec: 1203.36
//
Query:       EEA21839.1  [L=462]
Description: L-ornithine aminotransferase Car2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   2.3e-113  378.9   0.0   2.6e-113  378.7   0.0    1.0  1  Aminotran_3      Aminotransferase class-III
  ------ inclusion threshold ------
      0.051   12.9   0.0      0.099   11.9   0.0    1.4  1  Beta_elim_lyase  Beta-eliminating lyase
      0.084   12.0   0.0       0.62    9.2   0.0    2.1  2  Aminotran_1_2    Aminotransferase class I and II


Domain annotation for each model (and alignments):
>> Aminotran_3  Aminotransferase class-III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  378.7   0.0  4.4e-117  2.6e-113       2     405 ..      37     433 ..      36     434 .. 0.94

  Alignments for each domain:
  == domain 1  score: 378.7 bits;  conditional E-value: 4.4e-117
                  C-TTB--SCEEEEEEEBTEEEETTS-EEEESSHHHHTTTT-BT-HHHHHHHHHHHTT-S---TTTCEEHHHHHHHHHHHHHCT-..SEEEEESSHHHH CS
  Aminotran_3   2 vareednlllvitkaeGvyltdvdgkrylDlvssiavvnlGhahPkvvkavkeqaaklshvsfgaltnepalklaekllklapkgldkvflansGseA 99 
                  +a+++++l++v   a G+ ++d +g++ylD++s++++vn+Gh+hP++vka+ +qa  l + s +a+ n+   k+ae ++k ++   d+v+ + +G+eA
   EEA21839.1  37 AAHNYHPLPIVFACASGTSVWDPEGRHYLDFLSAYSAVNQGHCHPELVKALVDQASRLALSS-RAFYNDVFPKFAEFVTKFFGF--DMVLPMCTGAEA 131
                  688999999*************************************************9999.*******************99..************ PP

                  HHHHHHHHHHHHHHTS..HCTT-EEEEETTT---SSHHHHHHSS--TTTTTTCTTB-TSEEEE-TTBGGGTB-HHHHHHHHHHHHHHHHCHTCCCEEE CS
  Aminotran_3 100 vetAlKlarkyarekk..atektkiiafkgafHGrtlgalsvtgskkkyktlfgpflpevvrlkypdeevlkeneeeeaalleelealekkkkdevaA 195
                  vet +K+ark+ +++k   ++++ +++++++fHGrt++a+s++++ ++ ++++gp lp+v +     +  + +n+  +aal e++ea    +  ++aA
   EEA21839.1 132 VETGIKIARKWGYKVKgiPENQAIVLSVENNFHGRTFAAISMSSD-PESRDNYGPYLPNVGHCIPGTNKPIAYND--KAALREAFEA----AGSNLAA 222
                  *************9998888888999*******************.**************999888766666666..6666666666....89***** PP

                  EEE-SCETTTTSEB--CCHHHHHHHHHHHHT-EEEEE-TTTTTTTTSSSSGGGGCTS--SEEEE-GGGGTT.SS-EEEEEEHHHHTTS-TTSB--TTT CS
  Aminotran_3 196 vivEpiqgegGvvvaspeflaklrelckkhdvllivDEvqtGfGrTGklfAlehagvspDlmtlaKaltgG.lplsavlataevmqalapgshgsTfg 292
                  ++vEpiqge+G+vv+++++l+++r+lc+kh+vlli DE+qtG++rTGkl ++e+ g++pDl++l+Ka++gG +p+s+vl++++vm +++pg hgsT+g
   EEA21839.1 223 FLVEPIQGEAGIVVPDDDYLQEARALCDKHNVLLICDEIQTGIARTGKLLCHEWSGIKPDLVLLGKAISGGmYPVSCVLGRKDVMLTIEPGTHGSTYG 320
                  ************************************************************************************************** PP

                  T-HHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHCTT-TTEEEEEEETTEEEEEEBCCCETTC...HHHHHHHHHCTEE-EEETTTEEEE--- CS
  Aminotran_3 293 GnplacavalavleiieeekllenaqelgaalkegLeelqkkyevikevRgkGlmiaielkeeaevke...keilkkakekGvlilsaGdnvirllpp 387
                  Gnpl  ava+ +le+i +e+++++a++lg+++++gL++l++    i++vRgkGl+ ai + e+++      ++++  +k kG+l +++++n+irl+pp
   EEA21839.1 321 GNPLGSAVAIRALEVIRDENMVQHAEKLGHIFRDGLKALNSP--LIQTVRGKGLLNAIVIDESKTG-GhsaWDLCMLMKSKGLLAKPTHENIIRLAPP 415
                  ****************************************55..8**********99966666663.2478*************************** PP

                  TT--HHHHHHHHHHHHHH CS
  Aminotran_3 388 liitdeeidelleilkka 405
                  l+it++ei+ +l+i+k+ 
   EEA21839.1 416 LVITEAEIKSALDIIKQS 433
                  ***************986 PP

>> Beta_elim_lyase  Beta-eliminating lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   1.7e-05     0.099      34     167 ..     106     259 ..      85     261 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 1.7e-05
                      HHHHHHHHHHHTT-SEEEEES-HHHHHHHHHHHH--TTEEEEEETT..........-HHHHSSTTHHHHCC--EEEEE-EBTT........... CS
  Beta_elim_lyase  34 vnrLedavaelfgkeaalfvpqGtaAnsillkillqrgeevivtep..........ahihfdetgaiaelagvklrdlknkea........... 106
                      + ++++ v++ fg++ +l++ +G  A +  +ki  +++  ++ ++p          +++h ++  ai+  ++ + rd +++             
       EEA21839.1 106 FPKFAEFVTKFFGFDMVLPMCTGAEAVETGIKIA-RKWGYKVKGIPenqaivlsveNNFHGRTFAAISMSSDPESRDNYGPYLpnvghcipgtn 198
                      667889999************9977777777554.466666666666677777777999999999999999999999999999*********** PP

                      ...TBE-HHHHHHHS--S-TTS-EEEEEEEESSBTTTTTB---H.HHHHHHHHHHHHCT-EEEEE CS
  Beta_elim_lyase 107 ...GkmdlekleaaikevgaheekiklisltvTnntagGqvvsl.eelrevaaiakkygiplhlD 167
                          + d ++l++a ++ g+   + ++ +++      +G vv+  ++l+e++a+++k+++ l++D
       EEA21839.1 199 kpiAYNDKAALREAFEAAGS---NLAAFLVEPIQG-EAGIVVPDdDYLQEARALCDKHNVLLICD 259
                      ***999***********777...777777776666.47999986268***************999 PP

>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0     0.042   2.5e+02      19      80 ..      79     132 ..      70     141 .. 0.76
   2 ?    9.2   0.0    0.0001      0.62     164     295 ..     236     359 ..     199     430 .. 0.66

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.042
                    HHHHHHHHHHH..HHHHHTSTTST-BTTHHHHHHHHHHHHHCTCTTCHTTGGEGEEEESHHHHH CS
  Aminotran_1_2  19 tlpevakaeke..galaggtlneygpidglpeleealakflgrseklklkreaavvvgsGagal 80 
                      pe +ka  +  + la +++++y +    p++ e ++kf+g      ++    + +++Ga a+
     EEA21839.1  79 CHPELVKALVDqaSRLALSSRAFYNDVF--PKFAEFVTKFFG------FDMV--LPMCTGAEAV 132
                    456777777777788999*****99888..************......6665..6666666665 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.0001
                    B--HHHHHHHHHHHHHTTEEEEEEETTTTCBSSSSHTHHHHGGSTTSTTEEEEEESSSTTSSGGG-EEEEEEEHHHHHHHHHHHHHHTS..SHHHH CS
  Aminotran_1_2 164 vatleeleklldlakkynlllfvDeaYagfvfgsldavatranveeepnllivgslsKafGlaGeRvGyilgnaavvsqlrklsrpfls..ssllq 257
                    v++ + l++  +l++k+n+ll++De+  g + + +    ++++ +    +l++ + + + G++   v ++lg ++v  +++    + ++    l++
     EEA21839.1 236 VPDDDYLQEARALCDKHNVLLICDEIQTGIARTGKL---LCHEWSGIKPDLVLLGKAISGGMYP--VSCVLGRKDVMLTIEPGTHGSTYggNPLGS 326
                    3445568889999*************9998888652...2555555444666666666667777..777777666666665555553333333333 PP

                    HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS CS
  Aminotran_1_2 258 aavaaalsdallkqseleemrqrlqkrrkelrdeLael 295
                    a++  al+       + e+m+q+ +k+ + +rd+L++l
     EEA21839.1 327 AVAIRALEVI-----RDENMVQHAEKLGHIFRDGLKAL 359
                    3333333332.....34667777777777777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (462 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       320  (0.0178482); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 3278.93
//
Query:       EEA21840.1  [L=403]
Description: L-ornithine aminotransferase Car2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   6.1e-103  344.6   0.0     7e-103  344.4   0.0    1.0  1  Aminotran_3      Aminotransferase class-III
  ------ inclusion threshold ------
      0.038   13.3   0.0      0.074   12.3   0.0    1.4  1  Beta_elim_lyase  Beta-eliminating lyase
      0.076   12.2   0.0       0.73    8.9   0.0    2.0  2  Aminotran_1_2    Aminotransferase class I and II


Domain annotation for each model (and alignments):
>> Aminotran_3  Aminotransferase class-III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  344.4   0.0  1.2e-106    7e-103       2     374 ..      37     402 ..      36     403 .] 0.94

  Alignments for each domain:
  == domain 1  score: 344.4 bits;  conditional E-value: 1.2e-106
                  C-TTB--SCEEEEEEEBTEEEETTS-EEEESSHHHHTTTT-BT-HHHHHHHHHHHTT-S---TTTCEEHHHHHHHHHHHHHCT-..SEEEEESSHHHH CS
  Aminotran_3   2 vareednlllvitkaeGvyltdvdgkrylDlvssiavvnlGhahPkvvkavkeqaaklshvsfgaltnepalklaekllklapkgldkvflansGseA 99 
                  +a+++++l++v   a G+ ++d +g++ylD++s++++vn+Gh+hP++vka+ +qa  l + s +a+ n+   k+ae ++k ++   d+v+ + +G+eA
   EEA21840.1  37 AAHNYHPLPIVFACASGTSVWDPEGRHYLDFLSAYSAVNQGHCHPELVKALVDQASRLALSS-RAFYNDVFPKFAEFVTKFFGF--DMVLPMCTGAEA 131
                  688999999*************************************************9999.*******************99..************ PP

                  HHHHHHHHHHHHHHTS..HCTT-EEEEETTT---SSHHHHHHSS--TTTTTTCTTB-TSEEEE-TTBGGGTB-HHHHHHHHHHHHHHHHCHTCCCEEE CS
  Aminotran_3 100 vetAlKlarkyarekk..atektkiiafkgafHGrtlgalsvtgskkkyktlfgpflpevvrlkypdeevlkeneeeeaalleelealekkkkdevaA 195
                  vet +K+ark+ +++k   ++++ +++++++fHGrt++a+s++++ ++ ++++gp lp+v +     +  + +n+  +aal e++ea    +  ++aA
   EEA21840.1 132 VETGIKIARKWGYKVKgiPENQAIVLSVENNFHGRTFAAISMSSD-PESRDNYGPYLPNVGHCIPGTNKPIAYND--KAALREAFEA----AGSNLAA 222
                  *************9998888888999*******************.**************999888766666666..6666666666....89***** PP

                  EEE-SCETTTTSEB--CCHHHHHHHHHHHHT-EEEEE-TTTTTTTTSSSSGGGGCTS--SEEEE-GGGGTT.SS-EEEEEEHHHHTTS-TTSB--TTT CS
  Aminotran_3 196 vivEpiqgegGvvvaspeflaklrelckkhdvllivDEvqtGfGrTGklfAlehagvspDlmtlaKaltgG.lplsavlataevmqalapgshgsTfg 292
                  ++vEpiqge+G+vv+++++l+++r+lc+kh+vlli DE+qtG++rTGkl ++e+ g++pDl++l+Ka++gG +p+s+vl++++vm +++pg hgsT+g
   EEA21840.1 223 FLVEPIQGEAGIVVPDDDYLQEARALCDKHNVLLICDEIQTGIARTGKLLCHEWSGIKPDLVLLGKAISGGmYPVSCVLGRKDVMLTIEPGTHGSTYG 320
                  ************************************************************************************************** PP

                  T-HHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHCTT-TTEEEEEEETTEEEEEEBCCCETTC...HHHHHHHHHCTEE- CS
  Aminotran_3 293 GnplacavalavleiieeekllenaqelgaalkegLeelqkkyevikevRgkGlmiaielkeeaevke...keilkkakekGvli 374
                  Gnpl  ava+ +le+i +e+++++a++lg+++++gL++l++    i++vRgkGl+ ai + e+++      ++++  +k kG+l+
   EEA21840.1 321 GNPLGSAVAIRALEVIRDENMVQHAEKLGHIFRDGLKALNSP--LIQTVRGKGLLNAIVIDESKTG-GhsaWDLCMLMKSKGLLM 402
                  ****************************************55..8**********99966666653.24779**********986 PP

>> Beta_elim_lyase  Beta-eliminating lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   1.2e-05     0.074      34     167 ..     106     259 ..      85     261 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.2e-05
                      HHHHHHHHHHHTT-SEEEEES-HHHHHHHHHHHH--TTEEEEEETT..........-HHHHSSTTHHHHCC--EEEEE-EBTT........... CS
  Beta_elim_lyase  34 vnrLedavaelfgkeaalfvpqGtaAnsillkillqrgeevivtep..........ahihfdetgaiaelagvklrdlknkea........... 106
                      + ++++ v++ fg++ +l++ +G  A +  +ki  +++  ++ ++p          +++h ++  ai+  ++ + rd +++             
       EEA21840.1 106 FPKFAEFVTKFFGFDMVLPMCTGAEAVETGIKIA-RKWGYKVKGIPenqaivlsveNNFHGRTFAAISMSSDPESRDNYGPYLpnvghcipgtn 198
                      667889999************9977777777554.466666666666677777777999999999999999999999999999*********** PP

                      ...TBE-HHHHHHHS--S-TTS-EEEEEEEESSBTTTTTB---H.HHHHHHHHHHHHCT-EEEEE CS
  Beta_elim_lyase 107 ...GkmdlekleaaikevgaheekiklisltvTnntagGqvvsl.eelrevaaiakkygiplhlD 167
                          + d ++l++a ++ g+   + ++ +++      +G vv+  ++l+e++a+++k+++ l++D
       EEA21840.1 199 kpiAYNDKAALREAFEAAGS---NLAAFLVEPIQG-EAGIVVPDdDYLQEARALCDKHNVLLICD 259
                      ***999***********777...777777776666.47999986268***************999 PP

>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0     0.034   2.1e+02      19      80 ..      79     132 ..      70     141 .. 0.76
   2 ?    8.9   0.0   0.00012      0.73     164     249 ..     236     316 ..     199     373 .. 0.60

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.034
                    HHHHHHHHHHH..HHHHHTSTTST-BTTHHHHHHHHHHHHHCTCTTCHTTGGEGEEEESHHHHH CS
  Aminotran_1_2  19 tlpevakaeke..galaggtlneygpidglpeleealakflgrseklklkreaavvvgsGagal 80 
                      pe +ka  +  + la +++++y +    p++ e ++kf+g      ++    + +++Ga a+
     EEA21840.1  79 CHPELVKALVDqaSRLALSSRAFYNDVF--PKFAEFVTKFFG------FDMV--LPMCTGAEAV 132
                    456777777777788999*****99888..************......6665..6666666665 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.00012
                    B--HHHHHHHHHHHHHTTEEEEEEETTTTCBSSSSHTHHHHGGSTTSTTEEEEEESSSTTSSGGG-EEEEEEEHHHHHHHHHHHHH CS
  Aminotran_1_2 164 vatleeleklldlakkynlllfvDeaYagfvfgsldavatranveeepnllivgslsKafGlaGeRvGyilgnaavvsqlrklsrp 249
                    v++ + l++  +l++k+n+ll++De+  g + + +    ++++ +    +l++ + + + G++   v ++lg ++v  +++    +
     EEA21840.1 236 VPDDDYLQEARALCDKHNVLLICDEIQTGIARTGKL---LCHEWSGIKPDLVLLGKAISGGMYP--VSCVLGRKDVMLTIEPGTHG 316
                    3445568889999*************8888887552...2444444444566655555556666..66666655555555554444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (403 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       361  (0.020135); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2694.00
//
Query:       EEA21841.1  [L=813]
Description: mannosyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.4e-79  267.5  12.6    3.1e-79  267.1  12.6    1.1  1  Glyco_transf_22  Alg9-like mannosyltransferase family
  ------ inclusion threshold ------
       0.24   11.9   2.6        1.4    9.4   0.5    3.0  3  AtpR             N-ATPase, AtpR subunit


Domain annotation for each model (and alignments):
>> Glyco_transf_22  Alg9-like mannosyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  267.1  12.6   3.5e-83   3.1e-79       2     416 ..      39     511 ..      38     512 .. 0.86

  Alignments for each domain:
  == domain 1  score: 267.1 bits;  conditional E-value: 3.5e-83
  Glyco_transf_22   2 ifllllalrlllalltqtsfdpDEffqslEvahklvfgkgt...ltWEyspkygiRSylfllllalpyrllaelvadskiav.......lyapR 85 
                      i+l+l+a+r+l+al+++t+f+pDEffq+lE+a ++vfgk     +tWE+  +  +RS +++l++a++y++   +    +  +       ++ap+
       EEA21841.1  39 ILLFLVAFRILNALTVRTFFQPDEFFQALEPAWQVVFGKDSgawITWEW--RHELRSSIHPLFFAAVYYIAGSFAWIARLSPlnaaellIVAPK 130
                      6899**********************************9743349****..*****************998777666666666779999***** PP

  Glyco_transf_22  86 lllallsalidyylfravcrkygsei..akialllslsswglfvfstrtfsnslemlltsialyllsellsrenksss................ 161
                      + +a+++a +dyy++++ ++ yg e    + +l+l  +s   +++strtfsns e++lt++aly++++     n++                  
       EEA21841.1 131 IAQAIIAATGDYYTWELSNKIYGTESygGWATLALTALSPWQWFCSTRTFSNSAETTLTIVALYFWPWEWFLDNQEMDaeeeeereeedepdep 224
                      **********************988522467788889999***************************977666666557889************ PP

  Glyco_transf_22 162 .....nekylvavlliavlavliRptsallwlplvlflllrlvkkrsktflfliialvllvlllvlvlviliDslfYgkfvftplnflkyNvls 250
                            +++l + ll+a+la++ Rpt++++w+ +  f +   +++ + t+ f++    +++ ++vl+l++liD+lfYg + f++++fl  Nv +
       EEA21841.1 225 fesasRQSSLRKCLLLAALACVLRPTNIIIWACMAGFAV---YQRPWLTV-FILARESIFCGSAVLGLSVLIDRLFYGVWAFPIFQFLYINVAQ 314
                      ****9889999***********************66665...77777776.45554555566666699************************** PP

  Glyco_transf_22 251 nlsslyGvhPwyfYllqnlpnilgvlllavllgllvllsr...........kvsrlllllltilltLlvysllpHKElRFllpvlPlillsaav 333
                      +   +yG + w++Yl+q+ p++l + l+++l+gl+++l r            ++  ++l+   l++ +++s++ HKE RF++p+lP++ ++ a 
       EEA21841.1 315 SIAIFYGHNDWHYYLSQGYPLLLTTALPFTLIGLYKSL-RpgdsamispggPIK--FQLATVSLVMPAMLSIITHKEVRFIYPLLPVLHILTAD 405
                      *************************************5.448999999876333..467888888889******************99888877 PP

  Glyco_transf_22 334 lltrls......resakvskk...lsllvllllfnvvlalllglvhqagvillvevmseleetkrknrkekketssvy................ 402
                       l ++       +++a    +     +l +l+l+n+++a+++ lvh  g+i   +v+s l++   ++++ +    +++                
       EEA21841.1 406 PLVSFFlpaissSNNA----QmprRLTLLFLVLVNIFIAYYTTLVHAPGAI---DVLSYLRTRHDAHQEGY---GHLLaprplfgesdkpvqvl 489
                      7777765654222222....2356688899999******************...88888888886655333...4555577888********** PP

  Glyco_transf_22 403 ........vlkecyrtPsssyl 416
                              +l++c++tP+ s+l
       EEA21841.1 490 ppknmtvgFLMPCHSTPWRSHL 511
                      ********************97 PP

>> AtpR  N-ATPase, AtpR subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.5   0.00016       1.4      42      80 ..     232     270 ..     228     279 .. 0.86
   2 ?   -0.7   0.1      0.22   1.9e+03      34      81 ..     267     312 ..     264     315 .. 0.84
   3 ?    0.5   0.0     0.095   8.5e+02      16      33 ..     604     621 ..     603     624 .. 0.89

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00016
        AtpR  42 lllRlgivlagfyllaagglarlLaallGFllaRllllr 80 
                   lR +++la+++ + ++   ++ a+++GF ++++ +l+
  EEA21841.1 232 SSLRKCLLLAALACVLRPTNIIIWACMAGFAVYQRPWLT 270
                 579***************************999876655 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.22
        AtpR  34 palllvsslllRlgivlagfyllaagglarlLaallGFllaRllllrl 81 
                 p  +l+  +l+R  i+ + ++l  +    rl+ ++  F ++++l +++
  EEA21841.1 267 P--WLTVFILARESIFCGSAVLGLSVLIDRLFYGVWAFPIFQFLYINV 312
                 4..777777899999999999999999999999999999999998875 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.095
        AtpR  16 iyFggLwltvrrliaskr 33 
                 ++F++L  t+r++++s++
  EEA21841.1 604 VFFAQLEPTIRTSLRSSS 621
                 8************99975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (813 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1125  (0.0627475); expected 358.6 (0.02)
Passed bias filter:                      635  (0.0354175); expected 358.6 (0.02)
Passed Vit filter:                        73  (0.00407162); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.79u 0.31s 00:00:01.10 Elapsed: 00:00:00.47
# Mc/sec: 5195.29
//
Query:       EEA21842.1  [L=722]
Description: GTPase activating protein for Arf, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.8e-36  124.7   0.1    5.1e-36  123.3   0.1    1.8  1  ArfGap    Putative GTPase activating protein for Arf


Domain annotation for each model (and alignments):
>> ArfGap  Putative GTPase activating protein for Arf
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.3   0.1   2.9e-40   5.1e-36       3     112 ..      16     127 ..      14     132 .. 0.93

  Alignments for each domain:
  == domain 1  score: 123.3 bits;  conditional E-value: 2.9e-40
                 HHHHHCC.SCCCCB-TTT-SBS--EEETTTTEEE-HHHHHHHCCS.TTT--EEETTTS---HHHHHHHHHTCHHHHHHHHTTTC-TTTSG.-TTCGHHH CS
      ArfGap   3 alkellk.epenkvCaDCgakeptWaslnlgvflCieCsgvHrslgvhiskvrsltldkwedeelellkalgNkkaneileaklpkeekr.skssskek 99 
                 al+el++  p+n++CaDC+a +p Was++lgvflC++C + Hr++g+hiskv+slt+d+w++e++e +++ gN+ +n+ ++ ++ k + + + ++ +++
  EEA21842.1  16 ALHELIRtVPGNDRCADCQAGNPGWASWSLGVFLCMRCGSLHRKMGTHISKVKSLTMDSWTTEQVENMRKRGNAIVNKEYNPRNIKPDIPvDVDEADSA 114
                 5566666599************************************************************************998888888999***** PP

                 HHHHHHHHHTCHT CS
      ArfGap 100 reefirakYeekk 112
                 +e+fir+kYe++ 
  EEA21842.1 115 MERFIRQKYEHRI 127
                 *********9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (722 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       830  (0.0462937); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.27s 00:00:00.95 Elapsed: 00:00:00.45
# Mc/sec: 4870.01
//
Query:       EEA21843.1  [L=651]
Description: hypothetical protein PMAA_056340 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00046   20.2   2.4    0.00088   19.3   2.4    1.4  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   2.4   4.9e-08   0.00088       2      25 ..     228     250 ..     227     254 .. 0.93

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 4.9e-08
                 S-HHHHHCT---STSSSS-HHHHH CS
     Zn_clus   2 aCdnCrkkKvKCdakkPaCsnCkk 25 
                 aC++Cr  + KC+  +P C+ C+ 
  EEA21843.1 228 ACIRCRTLRMKCSDVTP-CGTCVG 250
                 9****************.****85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (651 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       762  (0.042501); expected 358.6 (0.02)
Passed bias filter:                      566  (0.031569); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.33s 00:00:00.98 Elapsed: 00:00:00.52
# Mc/sec: 3753.60
//
Query:       EEA21844.1  [L=889]
Description: aminopeptidase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.8e-90  303.7   3.9    1.1e-89  301.1   0.9    2.3  2  ERAP1_C         ERAP1-like C-terminal domain
    1.1e-85  286.7   0.7    1.9e-85  285.9   0.7    1.4  1  Peptidase_M1    Peptidase family M1 domain
    7.8e-54  182.7   1.3    7.8e-54  182.7   1.3    1.7  2  Peptidase_M1_N  Peptidase M1 N-terminal domain
  ------ inclusion threshold ------
      0.011   15.8   0.1      0.025   14.6   0.1    1.6  1  DUF2808         Protein of unknown function (DUF2808)


Domain annotation for each model (and alignments):
>> ERAP1_C  ERAP1-like C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.1     0.013        60       3      19 ..     120     136 ..     120     139 .. 0.89
   2 !  301.1   0.9   2.5e-93   1.1e-89       1     313 [.     543     859 ..     543     861 .. 0.96

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.013
                 EESGGG-SSSEEEE-HH CS
     ERAP1_C   3 llNdddtGyyrVnYdee 19 
                 +lNd++ G+yr +Y  +
  EEA21844.1 120 ILNDNMAGFYRSSYKTA 136
                 69************776 PP

  == domain 2  score: 301.1 bits;  conditional E-value: 2.5e-93
                 -EEESGGG-SSSEEEE-HHHHHHHHHHHHGGGS-HHHHHHHHHHHHHHHHTTSS-HHHHHHGGG.GGGG--SHHHHHHHHHHHHHHHHHHT.TST.THH CS
     ERAP1_C   1 lvllNdddtGyyrVnYdeeslaalleqllskklspldRaglisdafalaragelsaadlldlllgylanEtdylvwsqalsqlatlkslls.adp.lya 97 
                 ++++N+d++G yr++Y +e+la+l+e+++ ++l+++dRag+++d  ala ag+++++ ll+ll+g+  +E++++vw+++l+++++l++ +  +d+ +++
  EEA21844.1 543 FFKVNADHSGIYRTSYTPERLAKLGEAAKAGLLTVEDRAGMVADSGALASAGYQKTSGLLSLLKGF-NTESEFIVWNEMLTRVGSLRAAWLfEDKkTRD 640
                 79************************999*************************************.7********************99875556999 PP

                 HHHHHHHHHHHHHHHHHHH..T.TTS-HHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHCSTT-.S-HHHHHHHHHHHHHHS-HHHHHHHHHHHHC-S CS
     ERAP1_C  98 alkaflrklleplaeklgw..epgeshldaqlrslllsaacaagdpevveearklfkawlegddl.ippdlrwavycalaanggeaewdallerykdts 193
                 alkaf r++ +  a++lgw  +++++h  +q+++l+++ a++agdp  v++a+++fk++++gd + i+p++r++vy+++++ngge+e+da+l++y++++
  EEA21844.1 641 ALKAFQRAITSEKAHQLGWkfSDSDDHVLQQFKALMFGSAGSAGDPTIVAAAQDMFKRYIDGDRSaIHPNIRGSVYNIVLKNGGEKEYDAILNIYRTAT 739
                 *******************54467*************************************98855*****************************9988 PP

                 SHHHHHHHHHHHCC-S-HHHHHHHHHHCTTT..S-GGGHHHHHHHH.HSTTHHHHHHHHHHHCHCCHHHHTSSTS.CHHHHHHHHHTT--SHHHHHHHH CS
     ERAP1_C 194 apsekeaalralaatpdpellerllnfvlesdevrnqdlrallaglannpegrellwefvkenwdalakrwsgge.ildrivkgllpgftseeelaeie 291
                 +++ek++alr+l+a +d +l++r+l++++ ++evrnqd++++l++l+n+  g e+ w++++enwd++ +r++++  +l++i++ +   f++ee+l+e+e
  EEA21844.1 740 TSDEKNTALRSLGAAEDINLIRRTLDLAT-NGEVRNQDVYMPLSALRNHTTGVEERWKWLQENWDTILARFPPSLgMLGTIIQLSSVAFNTEEQLKEVE 837
                 77**************************7.99**************99***********************86456*********************** PP

                 HHHCHTT--GGGHHHHHHHHHH CS
     ERAP1_C 292 affadkdtpglrrtlkqaletv 313
                 affa kdt+g++r+++q+l+++
  EEA21844.1 838 AFFAPKDTKGFDRAVSQSLDAI 859
                 ********************98 PP

>> Peptidase_M1  Peptidase family M1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  285.9   0.7   4.2e-89   1.9e-85       1     218 []     252     469 ..     252     469 .. 1.00

  Alignments for each domain:
  == domain 1  score: 285.9 bits;  conditional E-value: 4.2e-89
                   HHHHHHHHHHHHHHHHHTS--SSSEEEEEEESSTTSSEEEETTEEEEEGGGC-SSTTTS-HHHHHHHHHHHHHHHHHHHBTTTEEESSGGGGHHHHH CS
  Peptidase_M1   1 yalevtkkllefleeyfkvpYplpkldlvalpdfsagAMEnwglityreelllvdpenssesdkrsvaeviaHElaHqWfGnlVtmkwWddlwLnEG 97 
                   ++le ++k+l f+e+ f+ +Yplpk+d+va+pdfsagAMEnwgl+tyr   ll+d+++s +s k++vaev+ HElaHqWfGnlVtm+ Wd lwLnEG
    EEA21844.1 252 FSLELAAKTLAFYEKAFDNEYPLPKMDMVAIPDFSAGAMENWGLVTYRVVDLLLDEKTSGASVKERVAEVVQHELAHQWFGNLVTMDFWDGLWLNEG 348
                   789********************************************************************************************** PP

                   HHHHHHHHHHHHHSCCCHCHHHHHHHCHHHHHHHHTSTTHHHSSGG-GSHHHHHHTSSHHHHHHHHHHHHHHHHHCTHHHHHHHHHHHHHHCTTEEE CS
  Peptidase_M1  98 fatyleylildklepewevseqllleeveealsedaldeshpitqevekpseidevFdsiaYeKGasllrmlekllgeevFqkglksYlkefkykna 194
                   fat++++++++ ++pew+v+++++++++++als d+l++shpi++ v++++ei+++Fd+i+Y+KG+s+lrm++k+lge+vF +g++ Y+++++y+n+
    EEA21844.1 349 FATWMSWYSCNVFYPEWKVWQTYVIDNLQSALSLDSLRSSHPIEVPVKRADEINQIFDAISYSKGSSVLRMISKYLGEDVFLQGVRDYIRKHAYGNT 445
                   ************************************************************************************************* PP

                   -HHHHHHHHHHCCCSCHHTHHHHH CS
  Peptidase_M1 195 etedlwdaleealnkdisevmdtw 218
                   +t dlw al +a++k ++evmd w
    EEA21844.1 446 QTGDLWAALAKASGKPVEEVMDVW 469
                   **********************99 PP

>> Peptidase_M1_N  Peptidase M1 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  182.7   1.3   1.7e-57   7.8e-54       1     186 []      27     217 ..      27     217 .. 0.92
   2 ?   -3.1   0.0       1.7   7.6e+03      96     109 ..     546     559 ..     543     562 .. 0.83

  Alignments for each domain:
  == domain 1  score: 182.7 bits;  conditional E-value: 1.7e-57
                     EEEEEEEEEEEETTTTEEEEEEEEEEEESS-ECEEEEEESSEEEECEEEEECTTCTCEEEEEEEECTTTTCEEEEECCEEETTCEEEEEEEEEEE CS
  Peptidase_M1_N   1 vpehYdldlkidlkektfkGsvtitlqlkeatseivldakdlkiksvslsaevksesvkidfkieqkdeelltiklkeslqqtskytLeieyege 95 
                     +p hYdl+l++d++++t++G+v i+l+++e+t++i+l++++l+i+s  ++ + +   ++ + + ++kd+++ t++++e+  + sk++L+ +++g 
      EEA21844.1  27 KPVHYDLTLEPDFEKFTYEGTVIIDLNVNEDTNSISLNTNQLEIHSSHVLVDGSVITSSSTLS-YDKDKQVTTVSFTETIPAGSKAQLKQTFTGI 120
                     699*****************************************9988887777666565555.67778889******9999************* PP

                     -BSSSSEEEEEEEEE.TSCEEEEEEEE-TTTTGGGTS-B--STTSEBEEEEEEEEETTSEEEESSECCCEEEET.....TCEEEEEEEEEESBEG CS
  Peptidase_M1_N  96 lndklaGlykstYtd.kgekkvvvvTqfeatdARsafPCfDePsvKAtftisikapkeetalSnmpeeesekle.....ngqkiteFeqtpkmst 184
                     lnd++aG+y+s+Y++ +g++ ++++Tq+e+tdAR+afPCfDeP+ KA+f+++++a+k++t lSnm++ ++++ +       +k ++F+++p+mst
      EEA21844.1 121 LNDNMAGFYRSSYKTaNGGTGYIASTQMEPTDARRAFPCFDEPALKAEFSVTLIADKQMTCLSNMDVASESEVDskitgGKRKAVKFNKSPVMST 215
                     *****************************************************************999988888777634455************ PP

                     GG CS
  Peptidase_M1_N 185 YL 186
                     YL
      EEA21844.1 216 YL 217
                     *9 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 1.7
                     -BSSSSEEEEEEEE CS
  Peptidase_M1_N  96 lndklaGlykstYt 109
                     +n +  G+y+++Yt
      EEA21844.1 546 VNADHSGIYRTSYT 559
                     578899*******8 PP

>> DUF2808  Protein of unknown function (DUF2808)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.1   5.5e-06     0.025      44     121 ..      50     130 ..      23     140 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 5.5e-06
     DUF2808  44 ltisqpdfvedikfdlkkveafvgttrnkgeklpleevv.wdkenrtieitfdePippgktvtvv..lknvrNPrfgGtYl 121
                 +++++ + ++ i+++++++e+  +    +g+ ++ +++   dk++++ ++ f e ip+g++ ++   +  + N +++G Y 
  EEA21844.1  50 IDLNVNEDTNSISLNTNQLEIHSSHVLVDGSVITSSSTLsYDKDKQVTTVSFTETIPAGSKAQLKqtFTGILNDNMAGFYR 130
                 4445555555899999****99999889999999766559********************988843377888888888885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (889 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       497  (0.0277205); expected 358.6 (0.02)
Passed bias filter:                      410  (0.022868); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.72u 0.29s 00:00:01.01 Elapsed: 00:00:00.46
# Mc/sec: 5794.20
//
Query:       EEA21845.1  [L=964]
Description: serine/threonine protein kinase (Pdd7p), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.5e-98  329.2   0.0    2.1e-98  328.7   0.0    1.2  1  DUF3543      Domain of unknown function (DUF3543)
    6.3e-62  209.3   0.0    1.1e-61  208.6   0.0    1.4  1  Pkinase      Protein kinase domain
    2.1e-41  141.9   0.0    3.6e-41  141.2   0.0    1.3  1  Pkinase_Tyr  Protein tyrosine kinase


Domain annotation for each model (and alignments):
>> DUF3543  Domain of unknown function (DUF3543)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  328.7   0.0  3.4e-102   2.1e-98       2     251 .]     647     927 ..     646     927 .. 0.92

  Alignments for each domain:
  == domain 1  score: 328.7 bits;  conditional E-value: 3.4e-102
     DUF3543   2 eedtklletleelaakadvvyefAevKfkqliPlapsskeglgaeeaksesnsssaiedeeltpeaivslseealvLYvkalsllakamdiaskwWkkk 100
                 +edtk+++ +e++a+++dvvy+fAevK+kqliPl+ps +++l +  +    +  s+ +d eltp+a+v+lseealvLYvkal+llak+mdia++wW++k
  EEA21845.1 647 DEDTKTVQYIEDCATRSDVVYGFAEVKYKQLIPLTPSVQTDLDKGGD----QVFSDSDDGELTPDAVVTLSEEALVLYVKALALLAKSMDIAGAWWARK 741
                 789***********************************996655543....3455668999************************************** PP

     DUF3543 101 n...........akkgekvvslrlnevvqwirerFnevleKaefvrlklqeaqkqlpedhp.....e........saessseevslsegvtaekLiYDr 175
                 n           ++++++ v +r+n+vvqw+r+rFnevleKaefvrlkl+e qk+lp+dhp     +        + ++s+++v++s+gvtaekL+YDr
  EEA21845.1 742 NrgevfgdtaqgTSTTNALVGTRINNVVQWVRNRFNEVLEKAEFVRLKLIEGQKRLPSDHPshpsnHslesnsagTLGTSTDHVVVSSGVTAEKLMYDR 840
                 **********998889999******************************************877661565665545555******************** PP

     DUF3543 176 AlemSraAAvnEltgedlkgCelaYetaiwmLealldedeeeenkkee...........eldeeDrkviekliksiknRLkalrkkl 251
                 AlemSraAA+nEltgedl+gCe+aY tai+mLea+l++de ++++k +            ++ eDrkv++kl++si++RL++lrkk+
  EEA21845.1 841 ALEMSRAAAINELTGEDLPGCEIAYITAIRMLEAVLESDELSQSNKGDragdpdkiyldGVQVEDRKVVSKLVSSIRSRLASLRKKI 927
                 **************************************999887776689***********************************96 PP

>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  208.6   0.0   1.8e-65   1.1e-61       1     259 [.      27     327 ..      27     332 .. 0.89

  Alignments for each domain:
  == domain 1  score: 208.6 bits;  conditional E-value: 1.8e-65
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHSCTTB--EEEEEEESSEEEEEEE--TTEBHHHHHHHHSS--HH. CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklkhpnivrlyevfeekdelylvleyveggeladllerkgslsee. 98 
                 y +le++G+Gsf++Vy++v+++ +  vA+K ++ +k +kk ++++++Ei ilk l+hp+iv l+++ e++++++lv+ey+  g+l  +++r+ +l ++ 
  EEA21845.1  27 YIRLEQIGRGSFATVYQGVHAKHRSYVAIKSVNLSKLNKKLKENLWSEIDILKGLHHPHIVALIDCHETTSHIHLVMEYCALGDLSLFIKRRDTLRDHr 125
                 56789*******************************************************************************999999766666666 PP

                 ....................HHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEET............................TTE...EEE-SGTTSE CS
     Pkinase  99 ....................eakkiakqilegleylHskgiiHrDlKpeNiLide............................kge...lKitDFGlak 146
                                      +++++kq+ ++l++l ++++iHrD+Kp+N+L+                              +     lKi+DFG+a+
  EEA21845.1 126 ytrdmiakypnprvgalnevVVRHFLKQLSSALKFLRDRNLIHRDIKPQNLLLCPspssyrnagtqvvpfkgsddsftplaglE-TlpmLKIADFGFAR 223
                 77777888888888888887*********************************9549999999999999988877776665551.1567********** PP

                 ESSSSCSBCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHHHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCT.SHH...HHHTTS-HHHHHHHHHH CS
     Pkinase 147 elessskltsfvgtseYlAPEvlkeneyskkvDvWslGvilyelltgkppfsgekgkekvekeldqlekilkilg.etkeklpeaseiseeakdllkkl 244
                  l s+s +++ +g++ Y+APE+l++++y++k+D+Ws+G +lye++ gkppf ++++ e  ++          i + + k  +p + eis ++k+l++ l
  EEA21845.1 224 SLPSTSLAETLCGSPLYMAPEILRYEKYDAKADLWSVGTVLYEMVVGKPPFMASNHVELLRR----------IERhKDKIRFPDELEISADIKSLIRGL 312
                 ****************************************************5555542222..........3332668899999999*********** PP

                 T-SSGCCSTTHHHHH CS
     Pkinase 245 lkkdpkkRltaeell 259
                 lk++p +R+ + e  
  EEA21845.1 313 LKMNPVERMNFPEFF 327
                 *********998876 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  141.2   0.0     6e-45   3.6e-41       5     255 ..      31     326 ..      28     330 .. 0.90

  Alignments for each domain:
  == domain 1  score: 141.2 bits;  conditional E-value: 6e-45
                  EEEEEESSEEEEEEEEETTTTSSEEEEEEEEES.TTSSHHHHHHHHHHHHHHHTS-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHT...... CS
  Pkinase_Tyr   5 kklGeGafGkVvegtlkgekekkevkVavKtlk.eeateeekeelleeakimkklkhpnivkllgvctkeepllivteyvkgGdLlkfLrkk...... 95 
                  +++G+G+f++V++g       k++  Va+K+++ ++ +++ ke+l +e++i+k l+hp+iv+l+ +   ++++ +v+ey++ GdL+ f++++      
   EEA21845.1  31 EQIGRGSFATVYQGVHA----KHRSYVAIKSVNlSKLNKKLKENLWSEIDILKGLHHPHIVALIDCHETTSHIHLVMEYCALGDLSLFIKRRdtlrdh 124
                  79************999....8999*******7245556669******************************************************** PP

                  .............CTTTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEE..............................TTEEEE-STTTH CS
  Pkinase_Tyr  96 .............ekekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlse..............................nkvvkisDfGLa 150
                               +  +l+   + +f  q+++++++L +++l+Hrd+  +N Ll+                                 + ki+DfG a
   EEA21845.1 125 rytrdmiakypnpRVGALNEVVVRHFLKQLSSALKFLRDRNLIHRDIKPQNLLLCPspssyrnagtqvvpfkgsddsftplagletLPMLKIADFGFA 222
                  **********988778888888999******************************9999*************************87779********* PP

                  EETTTSSEEEETTSSTSGGGGS-HHHHHHSEEEHHHHHHHHHHHHHHHHTTSSGTTTTSHHHHHHHHH...HTTEES-BBTTSBHHHHHHHHHHT-SS CS
  Pkinase_Tyr 151 rdiekddeyvkkeeaklpvkWmapEslkekkftsksDvWsfGvllwEiftlgespypglkneevlekl...kegkrlekpekcpeelyelmkkcweed 245
                  r++    +++ +e+   +  +mapE+l+++k+  k+D Ws G++l+E++  g+ p+   ++ e+l+++   k++ r +   ++++++++l++  ++ +
   EEA21845.1 223 RSL---PSTSLAETLCGSPLYMAPEILRYEKYDAKADLWSVGTVLYEMVV-GKPPFMASNHVELLRRIerhKDKIRFPDELEISADIKSLIRGLLKMN 316
                  ***...444444445555569***************************99.********9999999995223444666677899************** PP

                  GGGS--HHHH CS
  Pkinase_Tyr 246 peeRptfsel 255
                  p eR +f e 
   EEA21845.1 317 PVERMNFPEF 326
                  ******9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (964 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       416  (0.0232026); expected 358.6 (0.02)
Passed bias filter:                      361  (0.020135); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.76u 0.30s 00:00:01.06 Elapsed: 00:00:00.50
# Mc/sec: 5853.29
//
Query:       EEA21846.1  [L=957]
Description: phosphatidate cytidylyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (957 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       648  (0.0361426); expected 358.6 (0.02)
Passed bias filter:                      367  (0.0204696); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.75u 0.27s 00:00:01.02 Elapsed: 00:00:00.47
# Mc/sec: 6138.04
//
Query:       EEA21847.1  [L=785]
Description: ATP binding L-PSP endoribonuclease family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.7e-18   65.8   0.0    7.7e-12   45.2   0.0    3.6  3  Diphthami_syn_2  Diphthamide synthase
      3e-17   62.8   0.0    4.9e-09   36.3   0.0    4.1  4  Ribonuc_L-PSP    Endoribonuclease L-PSP
     0.0015   17.6   1.3     0.0024   16.9   1.3    1.2  1  Radial_spoke     Radial spokehead-like protein
     0.0015   18.3   0.1     0.0042   16.9   0.1    1.6  1  Cwf_Cwc_15       Cwf15/Cwc15 cell cycle control protein
  ------ inclusion threshold ------
        3.4    8.0   6.7         23    5.4   2.3    2.9  3  HBS1_N           HBS1 N-terminus
        4.6    6.9   5.9        2.6    7.7   1.1    2.5  3  FAM176           FAM176 family


Domain annotation for each model (and alignments):
>> Diphthami_syn_2  Diphthamide synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.3   0.0   0.00012      0.35       2      32 ..       7      38 ..       6      43 .. 0.84
   2 !    5.8   0.0    0.0028       8.3      32      72 ..      59      99 ..      53     107 .. 0.89
   3 !   45.2   0.0   2.6e-15   7.7e-12      66     205 ..     119     284 ..     112     299 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00012
  Diphthami_syn_2  2 kvavlysGGkDsilaLykalke.sevesLvsv 32
                      v++l+sGGkDs +++ + +++ + v  L ++
       EEA21847.1  7 NVIALISGGKDSLYSILHCIRNgHRVVALANL 38
                     589************99999887888877665 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0028
  Diphthami_syn_2 32 visenkesymfhvvnvhlvellaesvGiplikletaGeeek 72
                     +++e+ +s+m+ ++  +++ l   ++Gipl +  ++G+  +
       EEA21847.1 59 IEKEDIDSFMYQTIGHNVIPLYESALGIPLYRGDITGVAVD 99
                     778999**************************999998765 PP

  == domain 3  score: 45.2 bits;  conditional E-value: 2.6e-15
  Diphthami_syn_2  66 taGeeekevedLkgtlkkld.....veavviGaieseyqksriervCrelGlksvaPLWk...........kdpeelleeiveekfevivvavk 143
                       + e e+e+e L   l +++     ++av  Gai s yq++rie+v  +lGl ++a LW              +  ll  + + + +++++ v+
       EEA21847.1 119 EEEEGEDETESLMPLLSRIKrdiphANAVSAGAILSTYQRTRIENVAGRLGLVPLAFLWMfpflppsssssSGAGGLLDDMAAVGCDARIIKVA 212
                      444668899999999999988889999********************************6333333221111223578889999********** PP

  Diphthami_syn_2 144 aegldeslLGrridk.klidelkklsekygidka........gegGeaetlvlDaP..lfkkrlevkelekkw 205
                        gld+++L   +   k+   l+k+   y +d a        gegGe+etl lD+P  l+kk++ v+e +++ 
       EEA21847.1 213 SGGLDDDILWENVASpKTQRRLEKVMRPY-VDVAqtlrgavlGEGGEYETLALDGPafLWKKKIVVEESDREV 284
                      *********99885413333444443333.2222112222339*************44559999999988765 PP

>> Ribonuc_L-PSP  Endoribonuclease L-PSP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.3   0.0   1.6e-12   4.9e-09      34     118 ..     381     465 ..     347     467 .. 0.71
   2 !   16.8   0.0   1.7e-06    0.0051       4      39 ..     486     530 ..     484     549 .. 0.85
   3 ?    3.3   0.0     0.026        77      95     117 ..     650     672 ..     639     675 .. 0.83
   4 ?    0.2   0.0      0.23     7e+02      41      81 ..     714     759 ..     701     784 .. 0.65

  Alignments for each domain:
  == domain 1  score: 36.3 bits;  conditional E-value: 1.6e-12
                    SCB.-SSHHHHHHHHHHHHHHHHHHTT....--GGGEEEEEEEESSGGGHHHHHHHHHHHSSSSTS--EEEEEE-S.BSGGG-SEEEEEE CS
  Ribonuc_L-PSP  34 gelvegdveeqtrqalenlkavLaaag....aslsdvVkvtvFladiedfaevnevyaeafdelkeaParsaveVa.aLpkgakvEIeai 118
                    g     ++ +q +++ e+l+ +L++++    +s +d+V +tv+l +++dfa +n +y  +f+++ ++Par++v++  +Lp g++v I ++
     EEA21847.1 381 GP----TADAQMHAITEKLQTLLQSINthstISTNDIVFTTVLLRSMQDFAPMNGIYVSLFTKP-NPPARVTVACGdRLPDGVQVMISTV 465
                    33....455566666666666665554111168899****************************.7********9538999999988765 PP

  == domain 2  score: 16.8 bits;  conditional E-value: 1.7e-06
                    STTTSSS-BSEEE..........ETTEEEEEEE-SB-TTTSCB.-S CS
  Ribonuc_L-PSP   4 apaaaapYsqavk..........agnlvyvsGqlpldpetgelveg 39 
                    apa ++pYsqa++          +g lvy++Gq+pldp+++e+ +g
     EEA21847.1 486 APANIGPYSQAITvpytpqqegpSGSLVYIAGQIPLDPSSMEI-PG 530
                    78999******9999999999999**************99998.44 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.026
                    S--EEEEEE-SBSGGG-SEEEEE CS
  Ribonuc_L-PSP  95 eaParsaveVaaLpkgakvEIea 117
                      P  ++veV++Lp++ ++E +a
     EEA21847.1 650 VHPPCFTVEVEQLPRNSDIEWQA 672
                    458999*************9665 PP

  == domain 4  score: 0.2 bits;  conditional E-value: 0.23
                    HHHHHHHHHHHHHHHHHH.....TT--GGGEEEEEEEESSGGGHHH CS
  Ribonuc_L-PSP  41 veeqtrqalenlkavLaa.....agaslsdvVkvtvFladiedfae 81 
                    +e   ++ +++++avL++     ag sl++  + t + +++++++ 
     EEA21847.1 714 PETRSTNLRDRIDAVLSEigvveAGQSLAHCTMYTSYAQSVTHWEG 759
                    5556677788888888761111155677778888888888777765 PP

>> Radial_spoke  Radial spokehead-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   1.3   8.1e-07    0.0024     360     399 ..     106     145 ..      89     165 .. 0.75

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 8.1e-07
  Radial_spoke 360 eeeeeeeeeeeeeeeeeeeeepEtgpplltplseDasidd 399
                   ++++ eeeeeeeeeeee e e E   pll+ +++D  + +
    EEA21847.1 106 DQDKGEEEEEEEEEEEEGEDETESLMPLLSRIKRDIPHAN 145
                   4556666666666788888899*************65544 PP

>> Cwf_Cwc_15  Cwf15/Cwc15 cell cycle control protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.1   1.4e-06    0.0042     125     164 ..     106     145 ..      85     173 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 1.4e-06
                 ---------------------------------------- CS
  Cwf_Cwc_15 125 eeeesdddsdsdsdddddedetaeLlrELekikreraeek 164
                 ++++ ++++++++++++ edet+ L+  L +ikr+  + +
  EEA21847.1 106 DQDKGEEEEEEEEEEEEGEDETESLMPLLSRIKRDIPHAN 145
                 234555677777888888****************865555 PP

>> HBS1_N  HBS1 N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   2.3    0.0077        23       3      37 ..     108     142 ..     103     152 .. 0.70
   2 ?   -3.5   0.1       4.4   1.3e+04       8      21 ..     304     317 ..     300     337 .. 0.64
   3 ?    3.5   0.0      0.03        91      21      51 ..     384     414 ..     349     417 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.0077
      HBS1_N   3 ydseddeeeeeeeeLsdedqarLrscldevrevLg 37 
                   +e++eeeeeeee  + + + L+  l +++  ++
  EEA21847.1 108 DKGEEEEEEEEEEEEGEDETESLMPLLSRIKRDIP 142
                 33466666666667777788999999999988877 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 4.4
      HBS1_N   8 deeeeeee..eLsded 21 
                 ++  ++ee    ++ed
  EEA21847.1 304 KD--DDEEatAVTPED 317
                 22..222234777777 PP

  == domain 3  score: 3.5 bits;  conditional E-value: 0.03
      HBS1_N  21 dqarLrscldevrevLgeeaskvtvtekqik 51 
                   a++++ ++++++ L++ + + t+++++i+
  EEA21847.1 384 ADAQMHAITEKLQTLLQSINTHSTISTNDIV 414
                 569*******************99**99996 PP

>> FAM176  FAM176 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   1.1   0.00087       2.6      65      99 ..     107     141 ..      92     163 .. 0.56
   2 ?   -2.8   0.1       1.6   4.6e+03      73      81 ..     302     310 ..     280     333 .. 0.57
   3 ?    0.5   0.0      0.15   4.4e+02      41      81 ..     570     610 ..     565     628 .. 0.64

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00087
      FAM176  65 sekasededeeeeeeeedsseseaeeelsefertl 99 
                 ++k +e+e+eeeeeee ++++++    ls+++r +
  EEA21847.1 107 QDKGEEEEEEEEEEEEGEDETESLMPLLSRIKRDI 141
                 22223444444444444444444444456666655 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1.6
      FAM176  73 deeeeeeee 81 
                 de +++ee 
  EEA21847.1 302 DEKDDDEEA 310
                 222222222 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.15
      FAM176  41 lviriscrkdlerlkkkkkklkeesekasededeeeeeeee 81 
                 +v+   c+++ +r ++k +  ++  +  ++  d+ eee+ +
  EEA21847.1 570 IVFLARCHRQQQRGHQKARVAQRLWQAMHSRGDDVEEEDAD 610
                 56667788888877776666655555445555444444433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (785 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       773  (0.0431145); expected 358.6 (0.02)
Passed bias filter:                      655  (0.036533); expected 358.6 (0.02)
Passed Vit filter:                        78  (0.00435049); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.80u 0.30s 00:00:01.10 Elapsed: 00:00:00.46
# Mc/sec: 5088.08
//
Query:       EEA21848.1  [L=608]
Description: C2H2 transcription factor (Seb1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.9e-12   45.9  14.2    1.6e-06   28.3   1.5    2.8  2  zf-C2H2       Zinc finger, C2H2 type
    2.2e-07   31.1  12.1     0.0024   18.6   0.8    2.8  2  zf-C2H2_4     C2H2-type zinc finger
    2.7e-06   27.5   6.1    2.7e-06   27.5   6.1    3.1  3  zf-H2C2_2     Zinc-finger double domain
    1.6e-05   25.1   4.1      0.011   16.0   0.5    2.5  2  zf-C2H2_jaz   Zinc-finger double-stranded RNA-binding
    0.00027   21.2   5.5     0.0074   16.7   0.3    2.6  2  zf-met        Zinc-finger of C2H2 type
    0.00089   19.2  11.5      0.018   15.1   2.0    2.6  2  zf-C2H2_6     C2H2-type zinc finger
  ------ inclusion threshold ------
        0.2   11.3   8.1        1.4    8.6   0.4    2.7  3  zf_C2H2_ZHX   Zinc-fingers and homeoboxes C2H2 finger domain
       0.28   11.1   2.7         16    5.5   0.3    2.4  2  zf-LYAR       LYAR-type C2HC zinc finger
       0.74   10.3   7.4         79    3.8   7.4    2.6  1  zf-C2HE       C2HE / C2H2 / C2HC zinc-binding finger
        1.3    9.7   4.4        6.5    7.5   0.4    2.7  2  zf-C2H2_3rep  Zinc finger C2H2-type, 3 repeats
        1.7    8.4   9.3        8.6    6.2   0.1    2.5  2  zf-C2H2_11    zinc-finger C2H2-type
        1.9    8.9   5.1         13    6.2   0.5    2.4  2  zf-C2H2_2     C2H2 type zinc-finger (2 copies)
        2.2    8.4   6.4       0.76    9.9   2.4    2.1  2  zf-BED        BED zinc finger


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.2   5.3   9.3e-08   0.00013       1      23 []     480     503 ..     480     503 .. 0.98
   2 !   28.3   1.5   1.1e-09   1.6e-06       1      23 []     509     531 ..     509     531 .. 0.98

  Alignments for each domain:
  == domain 1  score: 22.2 bits;  conditional E-value: 9.3e-08
                 EEETTTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirt.H 23 
                 ++C+ C+++F+r+++LkrH+r+ H
  EEA21848.1 480 FVCTLCSRRFRRQEHLKRHYRSlH 503
                 89*******************999 PP

  == domain 2  score: 28.3 bits;  conditional E-value: 1.1e-09
                 EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirtH 23 
                 ++C++Cgk+F+r++nL +H rtH
  EEA21848.1 509 FECHECGKKFSRSDNLAQHARTH 531
                 89********************9 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   4.5   7.5e-06      0.01       1      24 []     480     503 ..     480     503 .. 0.96
   2 !   18.6   0.8   1.7e-06    0.0024       1      23 [.     509     531 ..     509     532 .. 0.97

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 7.5e-06
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlkthH 24 
                 f C++C+++F+++++L+rH ++ H
  EEA21848.1 480 FVCTLCSRRFRRQEHLKRHYRSLH 503
                 89*******************988 PP

  == domain 2  score: 18.6 bits;  conditional E-value: 1.7e-06
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlkth 23 
                 f+C+ Cgk Fs++++L +H +th
  EEA21848.1 509 FECHECGKKFSRSDNLAQHARTH 531
                 89********************9 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.1     0.051        70      13      25 ..     478     490 ..     473     491 .. 0.83
   2 !   27.5   6.1     2e-09   2.7e-06       1      25 [.     494     519 ..     494     520 .. 0.94
   3 ?   -1.6   0.1       3.2   4.4e+03       1       9 [.     523     531 ..     523     533 .. 0.89

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.051
   zf-H2C2_2  13 kpyeCplCdkaFk 25 
                 k + C lC+ +F 
  EEA21848.1 478 KTFVCTLCSRRFR 490
                 669*******995 PP

  == domain 2  score: 27.5 bits;  conditional E-value: 2e-09
   zf-H2C2_2   1 nLrrHirk.HtgekpyeCplCdkaFk 25 
                 +L+rH r+ Ht++kp+eC +C+k+F+
  EEA21848.1 494 HLKRHYRSlHTQDKPFECHECGKKFS 519
                 79*****77****************8 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 3.2
   zf-H2C2_2   1 nLrrHirkH 9  
                 nL +H r+H
  EEA21848.1 523 NLAQHARTH 531
                 7999****9 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.5     8e-06     0.011       2      23 ..     480     501 ..     479     503 .. 0.95
   2 !   10.0   0.2   0.00059      0.81       2      22 ..     509     529 ..     508     532 .. 0.89

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 8e-06
                  CBBTTTTBBBSSHHHHHCCTTS CS
  zf-C2H2_jaz   2 fYCvlCdKyFksenaldnHlkS 23 
                  f C lC++ F  ++ l+ H++S
   EEA21848.1 480 FVCTLCSRRFRRQEHLKRHYRS 501
                  88*******************9 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00059
                  CBBTTTTBBBSSHHHHHCCTT CS
  zf-C2H2_jaz   2 fYCvlCdKyFksenaldnHlk 22 
                  f+C +C K F+ + +l +H +
   EEA21848.1 509 FECHECGKKFSRSDNLAQHAR 529
                  9*****************955 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.3   5.3e-06    0.0074       1      22 [.     480     501 ..     480     501 .. 0.97
   2 !    6.3   0.8    0.0095        13       1      21 [.     509     529 ..     509     531 .. 0.91

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 5.3e-06
      zf-met   1 fyCelCnvtfnsesqlksHlqG 22 
                 f C lC ++f  + +lk H+++
  EEA21848.1 480 FVCTLCSRRFRRQEHLKRHYRS 501
                 78******************98 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0095
      zf-met   1 fyCelCnvtfnsesqlksHlq 21 
                 f+C  C ++f+   +l +H +
  EEA21848.1 509 FECHECGKKFSRSDNLAQHAR 529
                 78*****************65 PP

>> zf-C2H2_6  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.7   2.2    0.0013       1.8       2      22 ..     480     500 ..     479     505 .. 0.79
   2 !   15.1   2.0   1.3e-05     0.018       2      24 ..     509     531 ..     509     532 .. 0.97

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0013
   zf-C2H2_6   2 heCsvCsksFpslqaLggHkk 22 
                 ++C+ Cs++F+ +  L  H +
  EEA21848.1 480 FVCTLCSRRFRRQEHLKRHYR 500
                 99*********9977666655 PP

  == domain 2  score: 15.1 bits;  conditional E-value: 1.3e-05
   zf-C2H2_6   2 heCsvCsksFpslqaLggHkksH 24 
                 +eC++C+k F+  ++L  H ++H
  EEA21848.1 509 FECHECGKKFSRSDNLAQHARTH 531
                 8******************9999 PP

>> zf_C2H2_ZHX  Zinc-fingers and homeoboxes C2H2 finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.4     0.001       1.4       4      29 ..     479     504 ..     475     509 .. 0.89
   2 ?    7.3   0.7    0.0026       3.6       4      28 ..     508     531 ..     505     538 .. 0.86
   3 ?   -3.6   0.0       6.7   9.2e+03      31      44 ..     593     606 ..     591     607 .. 0.63

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.001
  zf_C2H2_ZHX   4 sFvCveCsfsakkfegLalHNarsHp 29 
                  +FvC+ Cs   ++ e L+ H    H+
   EEA21848.1 479 TFVCTLCSRRFRRQEHLKRHYRSLHT 504
                  7*******************999997 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0026
  zf_C2H2_ZHX   4 sFvCveCsfsakkfegLalHNarsH 28 
                   F C eC+    + ++La+H ar+H
   EEA21848.1 508 PFECHECGKKFSRSDNLAQH-ARTH 531
                  699*****************.6666 PP

  == domain 3  score: -3.6 bits;  conditional E-value: 6.7
  zf_C2H2_ZHX  31 etnftlqvvKrdnq 44 
                    +++l+ +Krd+ 
   EEA21848.1 593 DRRLSLKKRKRDET 606
                  55667777777764 PP

>> zf-LYAR  LYAR-type C2HC zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.1     0.012        17       1      15 [.     480     494 ..     480     499 .. 0.79
   2 ?    5.5   0.3     0.011        16       1      18 [.     509     527 ..     509     529 .. 0.87

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.012
     zf-LYAR   1 fsCiDCsktFdgdey 15 
                 f C  Cs +F+++e+
  EEA21848.1 480 FVCTLCSRRFRRQEH 494
                 78*********9654 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.011
     zf-LYAR   1 fsCiDCsktFdg.deykaH 18 
                 f C  C+k+F++ d+  +H
  EEA21848.1 509 FECHECGKKFSRsDNLAQH 527
                 6799********8888888 PP

>> zf-C2HE  C2HE / C2H2 / C2HC zinc-binding finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   7.4     0.057        79      24      49 ..     495     520 ..     455     531 .. 0.73

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.057
     zf-C2HE  24 lseeqskelilktpLkCtrCganfgn 49 
                 l+++  +    ++p++C+ Cg++f +
  EEA21848.1 495 LKRHYRSLHTQDKPFECHECGKKFSR 520
                 3333333355789********77765 PP

>> zf-C2H2_3rep  Zinc finger C2H2-type, 3 repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   0.4    0.0047       6.5      89     125 ..     467     503 ..     419     504 .. 0.71
   2 ?    2.9   0.2      0.12   1.6e+02      33      52 ..     509     528 ..     503     538 .. 0.64

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0047
  zf-C2H2_3rep  89 vennsenesgvrkfvcrfcGlkfdllpdlGrhhqaah 125
                    +++s   + ++ fvc +c  +f     l rh+++ h
    EEA21848.1 467 GRKQSLTDDPSKTFVCTLCSRRFRRQEHLKRHYRSLH 503
                   2244555677899*******************99877 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.12
  zf-C2H2_3rep  33 lqcipcgshfgnaeelwlhv 52 
                   ++c  cg +f+ +++l +h 
    EEA21848.1 509 FECHECGKKFSRSDNLAQHA 528
                   45666666666666666654 PP

>> zf-C2H2_11  zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   4.9     0.038        53       4      27 ..     479     502 ..     477     503 .. 0.87
   2 ?    6.2   0.1    0.0062       8.6       7      23 ..     511     527 ..     508     530 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.038
  zf-C2H2_11   4 tcqCleCGlcftSqlsLsRHlfIv 27 
                 t+ C++C + f  q  L+RH +  
  EEA21848.1 479 TFVCTLCSRRFRRQEHLKRHYRSL 502
                 778*****************8755 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.0062
  zf-C2H2_11   7 CleCGlcftSqlsLsRH 23 
                 C eCG +f+ +  L  H
  EEA21848.1 511 CHECGKKFSRSDNLAQH 527
                 *********88888877 PP

>> zf-C2H2_2  C2H2 type zinc-finger (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   0.5    0.0094        13      49      72 ..     478     501 ..     469     507 .. 0.83
   2 ?    4.2   0.8     0.039        53      50      73 ..     508     531 ..     500     536 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0094
   zf-C2H2_2  49 ekleClyCekefkslealreHmkk 72 
                 +++ C +C+++f+ +e+l+ H ++
  EEA21848.1 478 KTFVCTLCSRRFRRQEHLKRHYRS 501
                 5789*****************876 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.039
   zf-C2H2_2  50 kleClyCekefkslealreHmkkk 73 
                  +eC  C+k+f+  ++l +H +++
  EEA21848.1 508 PFECHECGKKFSRSDNLAQHARTH 531
                 489*****************9876 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   1.4       0.1   1.4e+02      14      43 ..     477     503 ..     473     504 .. 0.85
   2 ?    9.9   2.4   0.00055      0.76       4      38 ..     496     531 ..     493     531 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.1
                 SS--EETTTTEE----SSTHHHHHHHHHS- CS
      zf-BED  14 eqkavCryCgkilsrgggttnLkrHLrrkH 43 
                 ++  vC  C + + r     +LkrH r+ H
  EEA21848.1 477 SKTFVCTLCSRRFRRQ---EHLKRHYRSLH 503
                 56779**********9...9*****88877 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.00055
                 TSSS----GGSS--EETTTTEE----.SSTHHHHHH CS
      zf-BED   4 WkyftpvslkeqkavCryCgkilsrg.ggttnLkrH 38 
                 +++++ + ++++  +C  Cgk++sr+ +   + ++H
  EEA21848.1 496 KRHYRSLHTQDKPFECHECGKKFSRSdNLAQHARTH 531
                 79***********************95555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (608 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1065  (0.059401); expected 358.6 (0.02)
Passed bias filter:                      513  (0.0286129); expected 358.6 (0.02)
Passed Vit filter:                        72  (0.00401584); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.75u 0.33s 00:00:01.08 Elapsed: 00:00:00.56
# Mc/sec: 3281.85
//
Query:       EEA21849.1  [L=493]
Description: saccharolysin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   3.7e-137  458.3   0.0   4.2e-137  458.2   0.0    1.0  1  Peptidase_M3  Peptidase family M3


Domain annotation for each model (and alignments):
>> Peptidase_M3  Peptidase family M3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  458.2   0.0  2.3e-141  4.2e-137       2     457 ..      15     485 ..      14     486 .. 0.96

  Alignments for each domain:
  == domain 1  score: 458.2 bits;  conditional E-value: 2.3e-141
                   HHC-S-HHHHHHHHHHHCTTTCCSS..THHHHHHHHHHHHHHHHHHHTT-SSHHHHHHTTSTT-SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Peptidase_M3   2 lkespdrelRkeayeashskaaeqrntlensklleellklraelAkllgyesyaelaledkmaknpetvldfleelvkklrpllekelkllkelkkk 98 
                   + ++++ ++Rk+++ a+ +k++       n++l++e+++lr+e A+llg  +ya+++l d++  +pe+v  fl++l+ +l+  + +elk lk+lk +
    EEA21849.1  15 MDNARNSKTRKRLFLAFKNKCK------GNVPLFREMMILRDEAARLLGDANYAAYQLGDRLVTSPEKVNSFLDDLRCRLADRGAEELKRLKALKTA 105
                   78899*****************......78******************************************************************9 PP

                   C.....CT-SSS--CCCHHHHHHHHHCCCCS--CCCCGGG-BHHHHHHCHHHHHHHHHTEEEEEETTS.....--SSTT-EEEEEEET..TT-EEEE CS
  Peptidase_M3  99 e.....lglegelqpwDvaYYsekqreekydldqeelkeyfpletvleGllelfeeLfGikfveekdak...gevwhedVrkleVvde.ilseglig 186
                   +      g  +++  wD++YY +  +e++y++dq+e++e+fpl+++leG+l++f++LfG+ f e++ ++   + +w +dVr+++V+d+ +  ++++g
    EEA21849.1 106 DregepAGG-EQYCLWDYRYYNRLLLEKDYQIDQQEIAEFFPLNKTLEGMLDIFSRLFGLVFYEVDASNqtkDLTWYPDVRIFHVWDDdDDGGEFVG 201
                   975544333.59***************************************************99988888899**************999****** PP

                   EEEEEEC--TTS-SS-EEEEEE--B..TTS-B--EEEEEEEEE---BTTS--B--HHHHHHHHHHHHHHHHHHC--BSSGGGSTT-S-CCCCCHHHH CS
  Peptidase_M3 187 eiylDlyerkgKrggAasfglvksr..edgtrqlpviylllNftkpsskkPsLLtldevetLfHEfGHsmHsllsrteysnvsgtnvpidfvElpSq 281
                   ++ylDly+r+gKrg+ ++++l++++  e+g+r++p ++ll+ f+kp++ kP+LL+++++ tLfHE+GH++H+l+ +t+ys+++gt + +df E pS 
    EEA21849.1 202 YLYLDLYARDGKRGHPFNINLQPGFeyENGDRSYPSTVLLCSFAKPAGTKPCLLHHSDMVTLFHELGHGIHDLVRKTRYSRFHGTMTVLDFCETPSK 298
                   *************************766********************************************************************* PP

                   HHHHGGGSHHHHHCC-B-TTT--B--HHHHHHHHCCCCTTHHHHHHHHHHHHHHHHHCTT-TCCGHH....HHHHHHHHHHCTTSCTTBT....... CS
  Peptidase_M3 282 lmEnlltepevlkslskhyetgeaipeelleklikaknvnaalellrqlvfaafdqelHeeaeeeqilkkdlletyaelrkkflglpvap....... 371
                   ++En+++  + l+sls hyetge+ip++++++li++k+vn +l+ lrql+++ fd+ +H+  ++  il+ d+++ty+ l++ ++++  ++       
    EEA21849.1 299 MLENWCWLSRPLQSLSHHYETGEPIPQSMVDNLIRVKKVNSGLFYLRQLHISIFDLHIHQPPSHASILNTDITSTYNSLWQSITQMAGPSgettatd 395
                   *************************************************************************************999998888999 PP

                   .....TSSGGGC-CCCHTSS-TTTTCHHHHHHHHHHHHHHCCHHCCTT-CCHHHHHHHHTTTTTTSS-HHHHHHCCCSS---SHHHHHHCT CS
  Peptidase_M3 372 .....deasqasFghlfahgYaanYYsylyaevlaldifekffeedplnretGeryrkeiLsrGgskdplellkkflgrepsadallkalg 457
                        + + +a+F hl+   Y+a+YYsyl a v+ald+f+++f++dpln+e G+ryr+ +L++Ggs++++++l++flgre  ++a++++l+
    EEA21849.1 396 tggndWGHGYATFFHLL-SDYGAGYYSYLLADVYALDMFHSVFKSDPLNPEQGRRYRRMVLEKGGSQPEMKTLSDFLGREATTQAFYEELA 485
                   99888888888*****7.9********************************************************************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (493 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       368  (0.0205254); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 3432.35
//
Query:       EEA21850.1  [L=167]
Description: hypothetical protein PMAA_056410 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.025   14.9   0.0      0.034   14.5   0.0    1.4  1  Stap_Strp_tox_C  Staphylococcal/Streptococcal toxin, beta-gra
      0.074   13.6   0.7       0.36   11.4   0.4    2.2  2  Syntaxin-6_N     Syntaxin 6, N-terminal


Domain annotation for each model (and alignments):
>> Stap_Strp_tox_C  Staphylococcal/Streptococcal toxin, beta-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.0   3.8e-06     0.034      19      50 ..      82     114 ..      65     160 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 3.8e-06
  Stap_Strp_tox_C  19 savkidKkevTiqEldvkvRkyLikkyniY.ek 50 
                      + v + Kk    q ld+++R+yL++++  Y  +
       EEA21850.1  82 KIVDTVKKDPSSQNLDIQARHYLNSEHRKYvAN 114
                      5688999********************999433 PP

>> Syntaxin-6_N  Syntaxin 6, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.4     4e-05      0.36       5      79 ..      17      99 ..      16     114 .. 0.64
   2 ?   -1.6   0.0      0.47   4.2e+03      44      60 ..     143     159 ..     123     163 .. 0.52

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 4e-05
  Syntaxin-6_N  5 evkeeVqkslnkaeslyrrwerlledtsss......tseeldetrteLrkalrsie...wdledLeetvriveknpskfkidek 79
                  +v++  +  l++ ++l++r    +++ +s+         el+ +++e+ + l++ e   +  +dL + v++v+k+ps  ++d +
    EEA21850.1 17 SVRDSMNRLLEQSRNLHNRLAISRDE-HSPvyqyasLGAELRGASREVAQLLEEFEiekYMRDDLFKIVDTVKKDPSSQNLDIQ 99
                  58888999999999999999764444.443244555556666666666666655432224456666777888888877777654 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.47
  Syntaxin-6_N  44 teLrkalrsiewdledL 60 
                   ++L +  ++i+  ++dL
    EEA21850.1 143 SNLDEDRGEIRVSIQDL 159
                   33333334444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (167 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       792  (0.0441742); expected 358.6 (0.02)
Passed bias filter:                      641  (0.0357521); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.41u 0.27s 00:00:00.68 Elapsed: 00:00:00.41
# Mc/sec: 1214.97
//
Query:       EEA21851.1  [L=334]
Description: thioredoxin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      4e-35  121.3   0.0    6.4e-35  120.6   0.0    1.3  1  PITH           PITH domain
    7.5e-29   99.8   0.0    1.4e-28   98.8   0.0    1.4  1  Thioredoxin    Thioredoxin
    2.4e-06   27.1   0.0    5.6e-06   25.9   0.0    1.6  2  OST3_OST6      OST3 / OST6 family, transporter family
    3.1e-06   27.4   0.1    2.2e-05   24.7   0.0    2.2  1  Thioredoxin_8  Thioredoxin-like
    4.2e-06   27.2   0.4    2.1e-05   24.9   0.4    2.1  1  Thioredoxin_2  Thioredoxin-like domain
    1.9e-05   24.4   0.2      0.098   12.4   0.0    2.4  2  Redoxin        Redoxin
    0.00015   21.7   0.3     0.0046   16.9   0.2    2.3  2  AhpC-TSA       AhpC/TSA family
    0.00086   19.1   0.0     0.0015   18.3   0.0    1.3  1  Thioredoxin_9  Thioredoxin
     0.0028   17.5   0.0      0.005   16.6   0.0    1.3  1  NIF            NLI interacting factor-like phosphatase
  ------ inclusion threshold ------
      0.012   15.5   0.1       0.02   14.7   0.1    1.3  1  TraF           F plasmid transfer operon protein
      0.016   15.2   0.0      0.048   13.6   0.0    1.8  2  HyaE           Hydrogenase-1 expression protein HyaE
      0.054   13.7   0.1       0.12   12.6   0.1    1.5  1  Thioredoxin_7  Thioredoxin-like
      0.082   12.7   0.0       0.14   11.9   0.0    1.3  1  DIM1           Mitosis protein DIM1


Domain annotation for each model (and alignments):
>> PITH  PITH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  120.6   0.0   4.7e-38   6.4e-35       2     152 .]     145     315 ..     144     315 .. 0.86

  Alignments for each domain:
  == domain 1  score: 120.6 bits;  conditional E-value: 4.7e-38
        PITH   2 yqyIdlkkveclNese.egsvkkvlkksweerlde.....kk..yleSdaDeqLlihipFtqsvklksllikstkk........eeeesaPktiklfkN 84 
                 ++ + +k +++ N ++ +g++k ++++s+++ ld+     k+  ++eSd+DeqL+++ipF++++k++sl+i s           +e +++Pkt++l++N
  EEA21851.1 145 TDAVTIKDLDMANRDSeKGTAKIIFDNSKPSALDNnkgkgKEpdWVESDTDEQLMLYIPFNSTLKVHSLQITSLPPkesddgddDELPMRPKTLRLYTN 243
                 67899999*****8774666888898888888766555551157***************************7654489999998888999********* PP

        PITH  85 rkkkldFdda.s.eptqeielseed..eeketvelplrfvkfqnvssLtlffednnegedvtridyiglkGe 152
                 r ++l+F++a + +p+q++++++ed  ++++t++++lrfvkfq+v+s+++ff d ++++++ r+d+++++Ge
  EEA21851.1 244 RATILGFEEAeDiDPVQTVSIAPEDwdSKTGTAKVELRFVKFQKVNSMVIFFVDGDGDGEKIRVDRLRVIGE 315
                 **********5566******9866654578899**************************************7 PP

>> Thioredoxin  Thioredoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.8   0.0     1e-31   1.4e-28       4     102 ..       6     104 ..       3     105 .. 0.94

  Alignments for each domain:
  == domain 1  score: 98.8 bits;  conditional E-value: 1e-31
                  ESSHHHHHHHHTTTSSEEEEEEE-TTSHHHHCHHHHHHHHHHHCTT..TSEEEEEETTTSHHHHHHTT-SSSSEEEEEETTEEEEEEESS-HHHHHHH CS
  Thioredoxin   4 vltkenFeeevakekklvlveFyApwCghCkalaPeleklaeelkd..kvklakvdvdenedlakkyevegiPtlklfkngkevkkyegarekeklaa 99 
                  + +ke+F + + + ++ v+ +FyA+wCg+Cka+aP++e+la++l+   ++++ kv+vd+++d+ak y+v+++Pt+++fk g+ v ++ ga + +kl +
   EEA21851.1   6 ISSKEQFSSLLTS-STIVVTDFYADWCGPCKAIAPMYEQLANQLSRknQITFTKVNVDQQQDIAKAYGVTAMPTFIMFKRGRVVTTIRGADP-NKLSE 101
                  5678999999998.9*****************************9999******************************************99.89988 PP

                  HHH CS
  Thioredoxin 100 flk 102
                   ++
   EEA21851.1 102 AIR 104
                  876 PP

>> OST3_OST6  OST3 / OST6 family, transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.9   0.0     4e-09   5.6e-06      46     104 ..      31      84 ..       8     135 .. 0.85
   2 ?   -2.4   0.0       1.7   2.3e+03     131     153 ..     188     210 ..     170     217 .. 0.82

  Alignments for each domain:
  == domain 1  score: 25.9 bits;  conditional E-value: 4e-09
   OST3_OST6  46 CelCrefepefelvakswrkdekskskklfFakvdfdegkdvFqklglnsaPhlllfpp 104
                 C +C+ ++p +e++a++  ++     +++ F kv++d+ +d+ + +g++  P +++f+ 
  EEA21851.1  31 CGPCKAIAPMYEQLANQLSRK-----NQITFTKVNVDQQQDIAKAYGVTAMPTFIMFKR 84 
                 *******************99.....79*****************************97 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 1.7
   OST3_OST6 131 kfisertgvkirikrppnyskii 153
                 +++++ t++++ ++ p+n +  +
  EEA21851.1 188 DWVESDTDEQLMLYIPFNSTLKV 210
                 799999**999999999987665 PP

>> Thioredoxin_8  Thioredoxin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.0   1.6e-08   2.2e-05       3      53 ..      21      71 ..      19      86 .. 0.87

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 1.6e-08
                   EEEEEE--SSSHHHHHHHHHHHHHHHHHHHTTSEEEEEEE-SS-HHHHHHH CS
  Thioredoxin_8  3 vvlLyfgaswcppckaftpklkelyeklkkkkkveivyvsldkkeeefeky 53
                   +v+  f+a+wc pcka+ p   +l ++l+ k+++ +  v++d++++  ++y
     EEA21851.1 21 IVVTDFYADWCGPCKAIAPMYEQLANQLSRKNQITFTKVNVDQQQDIAKAY 71
                   78899**************************************98877776 PP

>> Thioredoxin_2  Thioredoxin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.9   0.4   1.5e-08   2.1e-05       7     105 ..      21      99 ..      17     103 .. 0.73

  Alignments for each domain:
  == domain 1  score: 24.9 bits;  conditional E-value: 1.5e-08
  Thioredoxin_2   7 pvlvvftdpdCpyCkklkkelkelddvtvrvllfplkpsfepkavaiwcakekkkafkdieenvelarkygvrgtPtivfldgkeivarlpGyvpa 102
                     v+++f++++C+ Ck++    ++l +  +r      k+++ +  v+++++++              a++ygv+++Pt++++   ++v++++G+  +
     EEA21851.1  21 IVVTDFYADWCGPCKAIAPMYEQLANQLSR------KNQITFTKVNVDQQQD-------------IAKAYGVTAMPTFIMFKRGRVVTTIRGAD-P 96 
                    6899************99999999444333......4555555555555555.............679*********88665555*******94.4 PP

  Thioredoxin_2 103 eel 105
                    ++l
     EEA21851.1  97 NKL 99 
                    455 PP

>> Redoxin  Redoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.9   0.1    0.0002      0.27      25      65 ..      14      56 ..       7      62 .. 0.73
   2 !   12.4   0.0   7.1e-05     0.098      89     141 ..      59     100 ..      49     106 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.0002
                H.HTTSEEEEEEESTTT-HHHHHTHH.HHHTHHHHHHCSTTTE CS
     Redoxin 25 e.fkgkkvvvnfvpgafcPtCsaehp.yleklaellkekgvdv 65
                + ++  ++vv+ + + +c++C+a +p y++  ++l +++ +++
  EEA21851.1 14 SlLTSSTIVVTDFYADWCGPCKAIAPmYEQLANQLSRKNQITF 56
                4477889999877778**********66666677766666555 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 7.1e-05
                 EEE-TTSHHHHHTT-TTEEE.GGGEEE-EEEEEEETTEEEEEEESSSCHTSTT CS
     Redoxin  89 vlsDgsaaftkalGlrleedaseglrtpryavidedgkvvylevepepetees 141
                 v +D++++++ka+G++         ++p+++++ + g+vv ++++++p +  s
  EEA21851.1  59 VNVDQQQDIAKAYGVT---------AMPTFIMF-KRGRVVTTIRGADPNK-LS 100
                 479***********88.........****9998.5688888999998854.44 PP

>> AhpC-TSA  AhpC/TSA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.2   3.3e-06    0.0046      26      74 ..      20      68 ..       7      70 .. 0.80
   2 !    6.9   0.0    0.0042       5.7      79     120 ..      51      87 ..      49      91 .. 0.72

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 3.3e-06
                SEEEEEEESTST-CCHHHHHHHHHHCHHHCC.CTTEEEEEEESSSCHHHH CS
    AhpC-TSA 26 kpvvlffypkdwcpvCttelpalaklyeefk.ergvevigvsvdspeshk 74
                 +vv  fy+  wc +C++ +p +++l++++  ++ ++   v+vd++++++
  EEA21851.1 20 TIVVTDFYAD-WCGPCKAIAPMYEQLANQLSrKNQITFTKVNVDQQQDIA 68
                4677778888.****************99984667899999999988765 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0042
                 H-H.SSE.EEE-TTSHHHHHTT-EETTTTECSCEEEEE-TTSB CS
    AhpC-TSA  79 keslnfp.llsDeegkvakaygvlkeekglalratfvidkegk 120
                 k++++f+ +  D+++++akaygv       a+++ +++++  +
  EEA21851.1  51 KNQITFTkVNVDQQQDIAKAYGVT------AMPTFIMFKRGRV 87 
                 56666642678************9......7777666665544 PP

>> Thioredoxin_9  Thioredoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   1.1e-06    0.0015      48     121 ..      26      99 ..       4     109 .. 0.71

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 1.1e-06
                    E--TT-HHHHHHHHHHHHHHHH...-TTEEEEEE-HHHHHHHTTTTTT-SS--SSEEEEE-TT--EEEEEESS-HHH CS
  Thioredoxin_9  48 ltedwCgDaavnvPvlakiael...npnievkillrdenlelmdqyltngaraiPtliildeegeelgvwgerPaev 121
                    + +dwCg + ++ P+ +++a++   +++i+++ +  d+++++ + y   g  a Pt+i+++++  + +  g  P+++
     EEA21851.1  26 FYADWCGPCKAIAPMYEQLANQlsrKNQITFTKVNVDQQQDIAKAY---GVTAMPTFIMFKRGRVVTTIRGADPNKL 99 
                    679*************999854111457888888888888888888...99********988754444455555555 PP

>> NIF  NLI interacting factor-like phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   3.6e-06     0.005      84     150 ..     140     209 ..     128     215 .. 0.84

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 3.6e-06
         NIF  84 escvkkkgeyvKdLsllgrdls...rvvivDdspdsfelqpengipiksffsdkkDneLlkllpllkela 150
                 + +  ++  ++KdL++ +rd +     +i+D+s+ s+  +++   + +++++ ++D++L+  +p+  +l+
  EEA21851.1 140 NYADVTDAVTIKDLDMANRDSEkgtAKIIFDNSKPSALDNNKGKGKEPDWVESDTDEQLMLYIPFNSTLK 209
                 4453447899*********88867789***************99999****99*******9999977665 PP

>> TraF  F plasmid transfer operon protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   0.1   1.5e-05      0.02     136     202 ..      26      85 ..      15      92 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.5e-05
        TraF 136 Fyrgkcpyceaqapilqafadky....glevraVsvdgrplpelpnarvdkgqaarlgvkrtPalvlvdpk 202
                 Fy+  c+ c+a ap+++++a++     +++   V+vd++++  +++         ++gv+ +P+++++++ 
  EEA21851.1  26 FYADWCGPCKAIAPMYEQLANQLsrknQITFTKVNVDQQQD--IAK---------AYGVTAMPTFIMFKRG 85 
                 9999**********999888764333389**********99..777.........***********99886 PP

>> HyaE  Hydrogenase-1 expression protein HyaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.0   3.4e-05     0.048      68     101 ..      60      93 ..      38      98 .. 0.81
   2 ?   -3.5   0.0       7.5     1e+04      27      37 ..     290     300 ..     280     318 .. 0.57

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 3.4e-05
                 THHHHHHHHHCCT-TSSSEEEEEETTEEEEEEES CS
        HyaE  68 dreqeealaerfgvlktPsllflrdgeylgvlak 101
                 + +q++ +a+ +gv+ +P++++++ g+++ ++ +
  EEA21851.1  60 NVDQQQDIAKAYGVTAMPTFIMFKRGRVVTTIRG 93 
                 4679999**********************99987 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 7.5
                 SEEEEEESS-S CS
        HyaE  27 gdavlllagDp 37 
                 ++ + ++ gD 
  EEA21851.1 290 SMVIFFVDGDG 300
                 34444555554 PP

>> Thioredoxin_7  Thioredoxin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.1   8.6e-05      0.12      19      81 ..      20      82 ..      12      83 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 8.6e-05
                   -EEE.EE--TT-HHHHHHHHHHHH-HHHHH.HHHT-EEEEESS--S-GGG.-TT---...SSEEEEE CS
  Thioredoxin_7 19 pvlv.ffgaswcftCqalerdflsdeevkaalaekfvllrvdvterdanileldeqg...vPvvafl 81
                   ++ v +f a+wc++C+a++ + ++  +     ++++ + +v+v++ ++   + +  g    P+++++
     EEA21851.1 20 TIVVtDFYADWCGPCKAIAPMYEQLANQLS-RKNQITFTKVNVDQQQDIA-KAY--GvtaMPTFIMF 82
                   566679************999999844444.7788889999998888722.222..23447777776 PP

>> DIM1  Mitosis protein DIM1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0    0.0001      0.14      18     101 ..      17     101 ..       3     108 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.0001
                 -SSSEEEEEEE-TT-HHHHHHHHHHHHHHHHTTTTEEE..EEEETTT--TTSCCCTT-.SSSEEEEEETTEEEEEE-SSS--SSB-S CS
        DIM1  18 eeerlvviRFGrdedaeClklDelLakiaeklknfavi..ylvdidevpdfnkmyele.dpvtilffyrnkhmkvDfgtgdnnKlnf 101
                 +++ +vv  F  d+   C  +  + ++ a++l++  +i    v++d+ +d  k y ++  p+ i+ f ++ ++   +  +d nKl  
  EEA21851.1  17 TSSTIVVTDFYADWCGPCKAIAPMYEQLANQLSRKNQItfTKVNVDQQQDIAKAYGVTaMPTFIM-F-KRGRVVTTIRGADPNKLSE 101
                 677899999***********************88776611568999************5555555.5.4444555555566777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (334 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       759  (0.0423336); expected 358.6 (0.02)
Passed bias filter:                      640  (0.0356964); expected 358.6 (0.02)
Passed Vit filter:                        67  (0.00373696); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.58u 0.32s 00:00:00.89 Elapsed: 00:00:00.49
# Mc/sec: 2064.14
//
Query:       EEA21852.1  [L=571]
Description: DnaJ domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.4e-19   67.7   0.4    9.2e-19   66.9   0.4    1.4  1  zf-CSL    CSL zinc finger
    6.4e-13   48.6   0.4    1.5e-12   47.5   0.4    1.7  1  DnaJ      DnaJ domain
  ------ inclusion threshold ------
       0.16   10.8   0.2       0.26   10.1   0.2    1.2  1  VSP       Giardia variant-specific surface protein


Domain annotation for each model (and alignments):
>> zf-CSL  CSL zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.9   0.4   1.5e-22   9.2e-19       2      59 .]     118     181 ..     117     181 .. 0.88

  Alignments for each domain:
  == domain 1  score: 66.9 bits;  conditional E-value: 1.5e-22
                 EEEGGGSEEETTTT....EEEEEETTSSE..EEEEHHHHHTT....--EEEETTSSEEEEEE-- CS
      zf-CSL   2 eveledfefdeeee....syyypCRCgde..FelteedleegaegaevvvqCssCSLwikVkfa 59 
                  v+led++ +++e+    s+y+ CRCgd+  F +te++le +a+++e++v+C++CSLwikV fa
  EEA21852.1 118 IVDLEDLIEQDDEAtgssSWYRGCRCGDKkgFIVTEDELEAEAQHGEILVGCRGCSLWIKVLFA 181
                 5889999986655544445******************************************985 PP

>> DnaJ  DnaJ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.5   0.4   2.5e-16   1.5e-12       1      63 []      13      93 ..      13      93 .. 0.81

  Alignments for each domain:
  == domain 1  score: 47.5 bits;  conditional E-value: 2.5e-16
                HHHHHHTSSTTG-.........HHHHHHHHHHHHHHHSTTTS.........CCHHHHHHHHHHHHHHHHHHTSHHHHHHHH CS
        DnaJ  1 dyYeiLgvskdas.........edeIkkaYrklalkyHPDkn.........pkdpeaeekFkeineAyevLsdpekRkqYD 63
                dyY+iL+++++ s          +++k+aY+k  lk+HPDk+         +++++++     i++Ay+vLsdp  R++YD
  EEA21852.1 13 DYYSILNIPSTDSssgklpiisRQQLKNAYHKALLKHHPDKSspspspapaSREQSNTYTVDDITNAYKVLSDPVLRAEYD 93
                8*********954456666666999***************9977776654333335555888******************9 PP

>> VSP  Giardia variant-specific surface protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.2   4.3e-05      0.26     361     395 ..     464     498 ..     455     500 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 4.3e-05
         VSP 361 ksGlstGaiaGisvavvvvvgGlvGflcwwficrG 395
                   Gls Ga aGis+  +  v  lvG+  w    rG
  EEA21852.1 464 NHGLSGGAKAGISLCSISCVLILVGLAAWRKTVRG 498
                 57***************************998888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (571 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       352  (0.019633); expected 358.6 (0.02)
Passed bias filter:                      295  (0.0164538); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.46
# Mc/sec: 3692.82
//
Query:       EEA21853.1  [L=360]
Description: cytochrome c peroxidase Ccp1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.9e-47  161.9   0.0      3e-47  161.3   0.0    1.2  1  peroxidase  Peroxidase


Domain annotation for each model (and alignments):
>> peroxidase  Peroxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  161.3   0.0   1.7e-51     3e-47      11     229 .]     109     326 ..      94     326 .. 0.91

  Alignments for each domain:
  == domain 1  score: 161.3 bits;  conditional E-value: 1.7e-51
                 CTTTHCHHHHHHHHHHHTT.......SSTTSCHHHTCCHHCSGGGTTTHHHHHHHHHHHHHCTT.....S-HHHHHHHHHHHHHHCTT--..--EE--- CS
  peroxidase  11 adrdmgpsllrlafhdcfv.......gGcdgsvlllepektapaNaslrkgldvldaikakleaacpgvvScADlialaardavelaggplvpvslGRr 102
                 +d+++gp l+rla+h +++       gG +g++++++pe++++aNa+l+ ++d+l+++ +k+++     +S+ Dl++la+ +a+++++gp +p+++GR+
  EEA21853.1 109 DDGSYGPVLVRLAWHASGTydketgtGGSNGATMRFAPESEHGANAGLKIARDFLEPVHEKFPW-----ISYGDLWTLAGVCAIQEMQGPAIPWRPGRQ 202
                 3899************9999999999**************************************.....*********************88******* PP

                 S-SSGGGS-S...-.-TS-HHHHHHHHHHHT--HHHHHHHHGGGGC-EESHH...........SS-GGGT....HHS.........EETS-STHHHHHH CS
  peroxidase 103 DatessasevsnlPdptasvdelrdkfarkgltdeelvaLsGaHtiGkahcssfsrlyaaadpaldaayaaekCasgntelvdld.tptkfdnsyfknl 200
                 Da +   +    lPd ++  d++r+ f r+g++d+e+vaL GaH++G+ah                ++y +           + d +pt f+n++f+ l
  EEA21853.1 203 DADVTACTPDGRLPDASKGQDHIRAIFGRMGFDDREMVALCGAHSLGRAHTD----------R---SGYDG-----------PWDfSPTVFTNEFFRLL 277
                 ***999844459**************************************33..........1...22332...........45779**********99 PP

                 CC....................T-EEEHHHHHHHHSCCCHHHHHHCCC- CS
  peroxidase 201 le....................krgllrsDqvllsdsetralvekyaes 229
                  +                    + ++l++D++l++d+e++++v++ya++
  EEA21853.1 278 ADekwawkkwsgpaqytdnktkTLMMLPTDLALVKDKEFKKHVDRYAKD 326
                 99********************************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (360 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       387  (0.0215851); expected 358.6 (0.02)
Passed bias filter:                      341  (0.0190195); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 2401.87
//
Query:       EEA21854.1  [L=808]
Description: DEAD/DEAH box helicase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.3e-47  161.8   0.0    8.3e-47  159.2   0.0    2.0  2  DEAD        DEAD/DEAH box helicase
    1.4e-29  102.7   0.0    1.3e-28   99.6   0.1    2.3  2  Helicase_C  Helicase conserved C-terminal domain
     0.0013   18.8   0.0     0.0031   17.6   0.0    1.6  1  ResIII      Type III restriction enzyme, res subunit
     0.0029   18.1   2.4      0.013   16.0   2.4    2.2  1  DUF2986     Protein of unknown function (DUF2986)
  ------ inclusion threshold ------
      0.066   12.9   0.0       0.14   11.8   0.0    1.5  1  DUF3334     Protein of unknown function (DUF3334)


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  159.2   0.0   2.3e-50   8.3e-47       1     175 [.     392     593 ..     392     594 .. 0.95
   2 ?   -0.1   0.0      0.19   6.7e+02      51     104 ..     648     701 ..     613     711 .. 0.68

  Alignments for each domain:
  == domain 1  score: 159.2 bits;  conditional E-value: 2.3e-50
                 -HHHHHHHHHHHTTCEEEEEESTTSSHHHHHHHHHHHHHHHS........TTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   1 tdiQaeaiplilgggdvlvaaeTGsGKTlaflipvlqivyet........kgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardql 91 
                 t+iQ++aip++l+ +d+++ a TGsGKT+ fl+p+l  ++e         ++++gp a+i++PtreLa+q+  ++kkf k+++ +v++i+gg++ ++q 
  EEA21854.1 392 TPIQRAAIPIALQSRDLIGVAVTGSGKTASFLLPLLVYIAELprldefewRKNDGPYAIILAPTRELAQQIEIEAKKFSKPLNFNVVSIVGGHSLEEQA 490
                 89**********************************999998*******99************************************************ PP

                 HHHHTTCSEEEEEHHHHHHHHHCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTT...................SEEEEEESSBSH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...................xxxxxxxxxxxx RF
        DEAD  92 skldngvdivvgtpgrlddllstgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklq...................rqvivlSATlpk 171
                   l+ g++i+++tpgrl+d l+++ l lsq+ ++++DEadr+ d gf++ +n+il +lp ++++   +                   rq+++ +AT+p+
  EEA21854.1 491 YSLRDGAEIIIATPGRLVDCLERRMLVLSQCCYVIMDEADRMIDLGFEEPVNKILDALPVTNEKPDTEeaedaqamsqhvggrdrryRQTMMYTATMPS 589
                 **********************************************************855554443379****************999*********9 PP

                 HHHH CS
                 xxxx RF
        DEAD 172 dvkk 175
                  v++
  EEA21854.1 590 AVER 593
                 9987 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.19
                 EEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTT.CSEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxx RF
        DEAD  51 livePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldng.vdivvgt 104
                 ++ +  +  +  +++++k+++   +++++   ++++++  l+ ++ng +d++v+t
  EEA21854.1 648 IVFVNIKRNCDAVAKDIKQMGFS-SVTLHGSKTQEQREAALASVRNGsTDVLVAT 701
                 55555555555666666666663.2334433445555555666677789999998 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.0      0.29     1e+03      13      61 ..     443     495 ..     431     504 .. 0.72
   2 !   99.6   0.1   3.6e-32   1.3e-28       5     111 .]     633     739 ..     629     739 .. 0.91

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.29
                 TTTTSEEEEEESSHHHHHH....HHHHHHHTTSTEEEESTTSTHHHHHHHHHH CS
  Helicase_C  13 eeeggkilifvntidrlek....vklllekkgikvavlhgelpqnereeileq 61 
                 +++g  ++i ++t++ +++    +k + +  +++v+ + g  + +e+  +l++
  EEA21854.1 443 KNDGPYAIILAPTRELAQQieieAKKFSKPLNFNVVSIVGGHSLEEQAYSLRD 495
                 66777899999999966553445666644449999999999998888877765 PP

  == domain 2  score: 99.6 bits;  conditional E-value: 3.6e-32
                 HHHHHHHHTTTTSEEEEEESSHHHHHH.HHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSSHHHHHH CS
  Helicase_C   5 allellkleeeggkilifvntidrlek.vklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprnvtsyiq 102
                 +l ++l + + +  i++fvn +++++  +k + ++ g+++++lhg+ +q++re++l++ ++g++dvL+atd a+rGid+p+v+lV+nf++ +n++sy +
  EEA21854.1 633 RLADILMSGQFQPPIIVFVNIKRNCDAvAKDI-KQMGFSSVTLHGSKTQEQREAALASVRNGSTDVLVATDLAGRGIDVPDVSLVVNFNMATNIESYTH 730
                 56666667788999***********9776666.4559************************************************************** PP

                 HHTTSSSTT CS
  Helicase_C 103 riGRtgRag 111
                 riGRtgRag
  EEA21854.1 731 RIGRTGRAG 739
                 *******97 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   8.5e-07    0.0031      27     152 ..     408     539 ..     377     551 .. 0.77

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 8.5e-07
                 EEEEESTTSTHHHHHHHHHHHH-S................-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--........-SEEEEEHHH CS
      ResIII  27 glikmaTGtGKTlvaaklierllkkgkee...........kflflvprkslleqtleefkkflseaykeigkkvsgdkkka.kekdstnkkilvttiqs 113
                 ++ ++ TG+GKT   +     +  + ++             +++l+p+++l +q + e kkf+++ + ++  +v g + ++   + ++ ++i+++t  +
  EEA21854.1 408 LIGVAVTGSGKTASFLLPLLVYIAELPRLdefewrkndgpYAIILAPTRELAQQIEIEAKKFSKPLNFNVVSIVGGHSLEEqAYSLRDGAEIIIATPGR 506
                 455678******87643333333333322355677799999***************9999999999888888888888777455568999********* PP

                 HHHTH........HHHTTT-SEEEEETGGGTTS.TTTHH CS
      ResIII 114 ldadseeeeeeseellrdrfdviiiDEaHrlgakkswre 152
                 l   +     e+  l  ++  ++i+DEa r+ +   ++e
  EEA21854.1 507 LVDCL-----ERRMLVLSQCCYVIMDEADRMID-LGFEE 539
                 *****.....88888899999*******99887.44444 PP

>> DUF2986  Protein of unknown function (DUF2986)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   2.4   3.5e-06     0.013      23      42 ..      92     111 ..      84     112 .. 0.77

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 3.5e-06
     DUF2986  23 hpsnKpkYISKAeRakleae 42 
                 + + Kpk+ SKAeR++l++e
  EEA21854.1  92 AAASKPKFLSKAERERLALE 111
                 4577*************987 PP

>> DUF3334  Protein of unknown function (DUF3334)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0     4e-05      0.14      62     130 ..     715     785 ..     712     787 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 4e-05
     DUF3334  62 vvinfsaeaaleiyrsymlnmGl.peeelalshtsdevsnvlGelmnqivGdftgkvskelqts.itqnqP 130
                 +v+nf  ++ +e y++ + + G  +++ +a+++  +e ++v+ +l   ++ + +++v +el+ +  +q++P
  EEA21854.1 715 LVVNFNMATNIESYTHRIGRTGRaGKSGVAITFLGNEDTDVMYDLKQMLMKSSISRVPEELRKHeAAQSKP 785
                 589*****************99625889*********************************8752567777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (808 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       972  (0.0542138); expected 358.6 (0.02)
Passed bias filter:                      461  (0.0257125); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.75u 0.31s 00:00:01.06 Elapsed: 00:00:00.50
# Mc/sec: 4857.50
//
Query:       EEA21855.1  [L=236]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-20   73.9   1.1    5.2e-10   39.8   0.1    2.8  4  Ank_2     Ankyrin repeats (3 copies)
    2.3e-12   47.2   0.9    4.1e-05   24.1   0.0    3.8  3  Ank_4     Ankyrin repeats (many copies)
    4.1e-11   42.1   3.1       0.44   11.3   0.0    5.8  6  Ank_3     Ankyrin repeat
    4.2e-10   39.7   1.4       0.74   10.2   0.0    4.4  4  Ank_5     Ankyrin repeats (many copies)
    0.00037   20.8   4.3        2.7    8.6   0.0    4.3  5  Ank       Ankyrin repeat


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       1.8   6.4e+03      61      73 ..      17      29 ..      13      45 .. 0.61
   2 !   23.8   0.0   1.4e-08   5.2e-05      10      79 ..      87     168 ..      80     171 .. 0.75
   3 !   39.8   0.1   1.5e-13   5.2e-10       7      80 ..     118     197 ..     112     199 .. 0.86
   4 !   21.4   0.0   7.9e-08   0.00028      29      74 ..     173     234 ..     171     236 .] 0.76

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 1.8
       Ank_2 61 arsghleivklLl 73
                ++s++++ ++ Ll
  EEA21855.1 17 CKSNRIDDIEALL 29
                3345555565555 PP

  == domain 2  score: 23.8 bits;  conditional E-value: 1.4e-08
       Ank_2  10 lelvklLl..egadpn.k...ngktaLhyAakngnleivklLleh.ad......ndgrtpLhyAarsghleivklLlekgadi 79 
                 +e+ k L+  + +d++     +g  +L + a ++n++ v++ leh ad      ++ +tpL +Aa +g+  +v+lLl++g ++
  EEA21855.1  87 FETYKVLIetKVVDISyYiplFG-DVLGIIADANNINWVRYCLEHgADpnknliEEFKTPLAAAAGNGNMGMVQLLLDYGTEP 168
                 56677777554466665245677.88999999999999*****9994443446655789*****999999******9999876 PP

  == domain 3  score: 39.8 bits;  conditional E-value: 1.5e-13
       Ank_2   7 ngnlelvklLl.egadpn.k...ngktaLhyAakngnleivklLleh.adndgrtpLhyAarsghleivklLlekgadin 80 
                  +n + v++ l +gadpn +   + kt+L +Aa ngn  +v+lLl++ ++ +   ++ +Aa++gh  iv+lLle+g++i+
  EEA21855.1 118 ANNINWVRYCLeHGADPNkNlieEFKTPLAAAAGNGNMGMVQLLLDYgTEPKESGAIVVAAEEGHAHIVELLLENGVEID 197
                 4556689999*999****73666669**********9999******998888888********************99986 PP

  == domain 4  score: 21.4 bits;  conditional E-value: 7.9e-08
       Ank_2  29 aLhyAakngnleivklLleh.............ad...ndgrtpLhyAarsghleivklLle 74 
                 a+ +Aa++g+ +iv+lLle+              d   +d  ++Lh A+ +gh e++ +L +
  EEA21855.1 173 AIVVAAEEGHAHIVELLLENgveideigvegppGDrrfEDLGSALHKAIIKGHDELAVWLTD 234
                 67799*************9776666666555552255655668**********999988875 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       1.9   6.9e+03      43      55 .]      17      29 ..      13      39 .. 0.67
   2 !   24.1   0.0   1.1e-08   4.1e-05       9      55 .]     116     162 ..     111     162 .. 0.92
   3 !   17.2   0.0   1.6e-06    0.0058       3      54 ..     172     232 ..     170     233 .. 0.75

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 1.9
       Ank_4 43 akrgnveilklLl 55
                +k ++++ ++ Ll
  EEA21855.1 17 CKSNRIDDIEALL 29
                5556666666664 PP

  == domain 2  score: 24.1 bits;  conditional E-value: 1.1e-08
       Ank_4   9 aisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 a ++++  vr++le+gad+n+ + ++  t+l  Aa +gn  +++lLl
  EEA21855.1 116 ADANNINWVRYCLEHGADPNKNLIEEFKTPLAAAAGNGNMGMVQLLL 162
                 44788888*************99999********************8 PP

  == domain 3  score: 17.2 bits;  conditional E-value: 1.6e-06
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaq....dnrs.....GetalhiAakrgnveilklL 54 
                 +a+  aa++g+  +v+lLle+g++i++     ++++       +alh+A+ +g+ e + +L
  EEA21855.1 172 GAIVVAAEEGHAHIVELLLENGVEIDEIgvegPPGDrrfedLGSALHKAIIKGHDELAVWL 232
                 68899*******************66665555443322221558*********97776666 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0       0.2   7.3e+02       9      23 ..      16      30 ..      13      37 .. 0.80
   2 ?   -1.7   0.0         2   7.3e+03       9      28 ..      50      68 ..      43      69 .. 0.67
   3 !    9.3   0.1   0.00054       1.9      10      30 ..     116     135 ..     111     136 .. 0.77
   4 !   11.3   0.0   0.00012      0.44       4      29 ..     144     168 ..     142     170 .. 0.91
   5 !    9.1   0.0   0.00062       2.2       7      30 ..     175     197 ..     172     198 .. 0.89
   6 !    5.8   0.0    0.0072        26       4      23 ..     215     234 ..     212     236 .] 0.88

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.2
       Ank_3  9 AarsgnleivkfLle 23
                 ++s++++ +++Ll+
  EEA21855.1 16 LCKSNRIDDIEALLK 30
                699999977999998 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 2
       Ank_3  9 AarsgnleivkfLlenkgad 28
                A+  +  +iv  +l  +ga 
  EEA21855.1 50 AVDLDAADIVACCLF-HGAT 68
                555555677888888.6775 PP

  == domain 3  score: 9.3 bits;  conditional E-value: 0.00054
       Ank_3  10 arsgnleivkfLlenkgadvn 30 
                 a ++n++ v+++le +gad+n
  EEA21855.1 116 ADANNINWVRYCLE-HGADPN 135
                 66667755******.9****9 PP

  == domain 4  score: 11.3 bits;  conditional E-value: 0.00012
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadv 29 
                 tpL  Aa +gn  +v++Ll+ +g ++
  EEA21855.1 144 TPLAAAAGNGNMGMVQLLLD-YGTEP 168
                 9*******************.99865 PP

  == domain 5  score: 9.1 bits;  conditional E-value: 0.00062
       Ank_3   7 hlAarsgnleivkfLlenkgadvn 30 
                  +Aa+ g+  iv++Lle +g++++
  EEA21855.1 175 VVAAEEGHAHIVELLLE-NGVEID 197
                 579**************.8*9987 PP

  == domain 6  score: 5.8 bits;  conditional E-value: 0.0072
       Ank_3   4 tpLhlAarsgnleivkfLle 23 
                 ++Lh A+  g+ e++ +L +
  EEA21855.1 215 SALHKAIIKGHDELAVWLTD 234
                 79***********9999977 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.1   0.1   0.00097       3.5      24      43 ..     116     135 ..     111     137 .. 0.91
   2 !   10.2   0.0   0.00021      0.74      13      39 ..     140     165 ..     135     173 .. 0.83
   3 !    9.2   0.0   0.00042       1.5      19      43 ..     173     197 ..     166     204 .. 0.88
   4 !    8.5   0.0    0.0007       2.5      18      35 ..     215     232 ..     207     236 .] 0.85

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00097
       Ank_5  24 akygaadvvrlLlargadln 43 
                 a +++ ++vr++l++gad+n
  EEA21855.1 116 ADANNINWVRYCLEHGADPN 135
                 5589**************98 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.00021
       Ank_5  13 dgggntpLhvAakygaadvvrlLlarg 39 
                 ++++ tpL  Aa +g+  +v+lLl++g
  EEA21855.1 140 EEFK-TPLAAAAGNGNMGMVQLLLDYG 165
                 5555.*******************776 PP

  == domain 3  score: 9.2 bits;  conditional E-value: 0.00042
       Ank_5  19 pLhvAakygaadvvrlLlargadln 43 
                 ++ vAa+ g+a +v+lLl++g+ ++
  EEA21855.1 173 AIVVAAEEGHAHIVELLLENGVEID 197
                 6889****************99875 PP

  == domain 4  score: 8.5 bits;  conditional E-value: 0.0007
       Ank_5  18 tpLhvAakygaadvvrlL 35 
                 ++Lh A+ +g+ +++ +L
  EEA21855.1 215 SALHKAIIKGHDELAVWL 232
                 89*************998 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.1       2.1   7.6e+03      15      25 ..      56      67 ..      44      69 .. 0.59
   2 ?    2.3   0.0     0.072   2.6e+02      16      28 ..     122     135 ..     111     137 .. 0.80
   3 !    8.6   0.0   0.00074       2.7       4      25 ..     144     166 ..     143     169 .. 0.84
   4 !    8.1   0.0    0.0011         4       9      27 ..     177     196 ..     173     199 .. 0.85
   5 ?   -1.4   0.0       1.1     4e+03       4      14 ..     215     225 ..     215     232 .. 0.71

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 2.1
                HHHHHHHH.TTT CS
         Ank 15 kriiklLL.hGA 25
                ++i+   L hGA
  EEA21855.1 56 ADIVACCLfHGA 67
                456666566776 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.072
                 HHHHHHH.TTTSTT CS
         Ank  16 riiklLL.hGAnln 28 
                 + +++ L hGA++n
  EEA21855.1 122 NWVRYCLeHGADPN 135
                 46788899*****9 PP

  == domain 3  score: 8.6 bits;  conditional E-value: 0.00074
                 BHHHHHHHHTTHHHHHHHH.TTT CS
         Ank   4 TPLHlAatngkkriiklLL.hGA 25 
                 TPL  Aa ng+  +++lLL +G 
  EEA21855.1 144 TPLAAAAGNGNMGMVQLLLdYGT 166
                 9******888888******6685 PP

  == domain 4  score: 8.1 bits;  conditional E-value: 0.0011
                 HHHHTTHHHHHHHH.TTTST CS
         Ank   9 AatngkkriiklLL.hGAnl 27 
                 Aa +g+++i++lLL +G ++
  EEA21855.1 177 AAEEGHAHIVELLLeNGVEI 196
                 8899**********889765 PP

  == domain 5  score: -1.4 bits;  conditional E-value: 1.1
                 BHHHHHHHHTT CS
         Ank   4 TPLHlAatngk 14 
                 ++LH A+  g+
  EEA21855.1 215 SALHKAIIKGH 225
                 58999985554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (236 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       408  (0.0227564); expected 358.6 (0.02)
Passed bias filter:                      396  (0.0220871); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.45
# Mc/sec: 1584.22
//
Query:       EEA21856.1  [L=587]
Description: mRNA splicing protein (Prp39), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.9e-07   29.2  13.6      0.012   16.4   0.3    8.1 10  TPR_14    Tetratricopeptide repeat
    1.1e-06   28.8   2.4    6.6e-05   23.0   0.1    3.1  3  Suf       Suppressor of forked protein (Suf)
  ------ inclusion threshold ------
      0.011   16.2   0.0        6.7    7.3   0.0    2.8  2  TPR_19    Tetratricopeptide repeat
      0.024   15.0   0.4         10    6.8   0.0    4.7  5  TPR_17    Tetratricopeptide repeat
      0.077   13.3   0.2       0.81   10.0   0.0    2.7  2  TPR_12    Tetratricopeptide repeat
        1.4    9.2   0.0        1.4    9.2   0.0    4.5  6  Gla       Vitamin K-dependent carboxylation/gamma-carboxyglut


Domain annotation for each model (and alignments):
>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.0      0.66     2e+03      25      43 ..      20      38 ..      14      38 .. 0.77
   2 ?   -0.1   0.0      0.78   2.3e+03      21      44 .]      60      83 ..      54      83 .. 0.87
   3 ?    3.0   0.0     0.078   2.3e+02       4      42 ..      77     115 ..      74     117 .. 0.81
   4 ?    1.0   0.0      0.34     1e+03       4      27 ..     149     172 ..     147     173 .. 0.88
   5 ?   -2.0   0.1       3.2   9.6e+03       6      21 ..     179     194 ..     178     196 .. 0.73
   6 ?   -3.2   0.1         6   1.8e+04       6      19 ..     208     221 ..     203     224 .. 0.71
   7 !   16.4   0.3   3.9e-06     0.012       4      43 ..     280     319 ..     277     320 .. 0.96
   8 ?    2.6   0.0      0.11   3.1e+02       3      42 ..     350     389 ..     348     391 .. 0.86
   9 !    6.4   0.0    0.0065        19       7      41 ..     388     422 ..     382     429 .. 0.81
  10 ?   -0.6   0.0       1.1   3.3e+03      10      41 ..     429     461 ..     420     463 .. 0.72

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.66
      TPR_14 25 rralalaPddaeawlllaq 43
                ++ l  +Pd+ e+w  l++
  EEA21856.1 20 EAELVEDPDNFETWEKLVR 38
                4446689*******99875 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.78
      TPR_14 21 iallrralalaPddaeawlllaql 44
                ++ ++r la++P    +w  +a+l
  EEA21856.1 60 RNSYDRFLAKFPLLFGYWKKYADL 83
                67899*******999999999976 PP

  == domain 3  score: 3.0 bits;  conditional E-value: 0.078
      TPR_14   4 llalaeallalGdpdeAiallrralalaPddaeawllla 42 
                 ++++a++++    +++A+ +++r +a  P++ ++w+ + 
  EEA21856.1  77 WKKYADLEFSIAGTEAAEMVYERGVASIPTSVDLWTNYC 115
                 6666666666666899*******************9885 PP

  == domain 4  score: 1.0 bits;  conditional E-value: 0.34
      TPR_14   4 llalaeallalGdpdeAiallrra 27 
                 + ++ e++++l+ +d+  ++l r+
  EEA21856.1 149 WDKYIEFEERLEAFDKIFDILGRV 172
                 899*************99988775 PP

  == domain 5  score: -2.0 bits;  conditional E-value: 3.2
      TPR_14   6 alaeallalGdpdeAi 21 
                 ++a+++++ +++++ +
  EEA21856.1 179 QYARYFERYRQLAQGR 194
                 6888888888887765 PP

  == domain 6  score: -3.2 bits;  conditional E-value: 6
      TPR_14   6 alaeallalGdpde 19 
                  +ae+++a+++p+ 
  EEA21856.1 208 YRAEIEAAADQPAP 221
                 56888888888874 PP

  == domain 7  score: 16.4 bits;  conditional E-value: 3.9e-06
      TPR_14   4 llalaeallalGdpdeAiallrralalaPddaeawlllaq 43 
                 +++++++++a G +++ + l++r+l ++   +e+wl++a+
  EEA21856.1 280 WKRYLDFEEAEGSYARIVFLYERCLVTCAHYDEFWLRYAR 319
                 999************************************8 PP

  == domain 8  score: 2.6 bits;  conditional E-value: 0.11
      TPR_14   3 allalaeallalGdpdeAiallrralalaPddaeawllla 42 
                 ++l +a +++ +++ d A+++ +++l   P++ e+   la
  EEA21856.1 350 VRLHYAYFEEMSERVDVARDIHEAILLNLPNHVETIVSLA 389
                 67899*********************99999988766555 PP

  == domain 9  score: 6.4 bits;  conditional E-value: 0.0065
      TPR_14   7 laeallalGdpdeAiallrralalaPddaeawlll 41 
                 la + ++ G++++Ai++++ ++++   da++  +l
  EEA21856.1 388 LANLSRRHGKLEDAIDVYKSRIETLGFDAATKAAL 422
                 78888999**************9877666655554 PP

  == domain 10  score: -0.6 bits;  conditional E-value: 1.1
      TPR_14  10 alla.lGdpdeAiallrralalaPddaeawlll 41 
                 + ++  G  ++A+++++   +++ d++++w+++
  EEA21856.1 429 LVWRvKGSSEDARQVFQNNQQTCLDSRAFWTRY 461
                 445435888999999998778888888888876 PP

>> Suf  Suppressor of forked protein (Suf)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.0   0.1   2.2e-08   6.6e-05      41     190 ..      80     243 ..      54     278 .. 0.75
   2 ?    3.3   0.3     0.022        67     110     150 ..     280     320 ..     251     345 .. 0.77
   3 ?    0.6   0.0      0.15   4.5e+02      89     152 ..     440     509 ..     431     586 .. 0.57

  Alignments for each domain:
  == domain 1  score: 23.0 bits;  conditional E-value: 2.2e-08
         Suf  41 sAllEyyiskdkkvAtkIFelGlKkFpedeefvlkYldyLisln.ddnnaRvlfekvvsklskekeakelykkfleyestfgdlssilklekRmeelfp 138
                  A lE+ i+  ++ A  ++e+G+   p++ +   +Y  + ++ n d++ +R lfe+  + +  +  a++ ++k++e+e +    ++i  +  R+  ++ 
  EEA21856.1  80 YADLEFSIAGTEA-AEMVYERGVASIPTSVDLWTNYCAFKVETNhDSDVIRELFERGAACVGLDFLAHPFWDKYIEFEERLEAFDKIFDILGRV--IYI 175
                 6889999988888.****************************99455679***********99999*********************9988885..566 PP

         Suf 139 edskleqfvdRYklkn....ldpikkrelksetkqeeekallqkkee..qaaslees..........k 190
                   ++ ++  +RY+       l++ ++ e+ s+ + e e+a +q++ +  ++a++e++          +
  EEA21856.1 176 PMHQYARYFERYRQLAqgrpLNELAPPEILSQYRAEIEAAADQPAPGarSEAEIERDlrlrldtyhlE 243
                 67788888888875432222677777777777777766666666555444444444467777776662 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.022
         Suf 110 ykkfleyestfgdlssilklekRmeelfpedskleqfvdRY 150
                 +k++l++e   g+ + i+ l +R+ ++    ++  +  +R+
  EEA21856.1 280 WKRYLDFEEAEGSYARIVFLYERCLVTCAHYDEFWLRYARW 320
                 ***********************999887655544444444 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.15
         Suf  89 aRvlfekvvsklskekeakelykkfleyestfgdlssilkle.kRmeelfpe........dskleqfvdRYkl 152
                 aR +f++  ++  +    +  ++++l +e ++   s +  ++ +R+++++++         ++++++v+ Y +
  EEA21856.1 440 ARQVFQNNQQTCLDS---RAFWTRYLLFELEQPTTSDTETVQhERIKKVVDDlrhngtlpAEAVKELVQNYMV 509
                 555555555554443...3677777777777776666666642466666666555555555555555555544 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   0.0    0.0022       6.7       3      50 ..     289     337 ..     288     342 .. 0.87
   2 ?    5.8   0.0    0.0068        20       5      50 ..     362     407 ..     359     424 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0022
      TPR_19   3 aegdyaeAlalleqalqedpknaearllLAeallal.gqldeAealLda 50 
                 aeg ya+ + l+e+ l   ++++e +l++A+ + a+ g  +e +++ ++
  EEA21856.1 289 AEGSYARIVFLYERCLVTCAHYDEFWLRYARWMSAQpGKEEEVRNIYQR 337
                 79*****************************998887777776666655 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0068
      TPR_19   5 gdyaeAlalleqalqedpknaearllLAeallalgqldeAealLda 50 
                 ++ + A ++ e++l   p++ e    LA++    g l++A+++ + 
  EEA21856.1 362 ERVDVARDIHEAILLNLPNHVETIVSLANLSRRHGKLEDAIDVYKS 407
                 57789999********************************998776 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0      0.77   2.3e+03       8      18 ..      25      35 ..      19      37 .. 0.80
   2 ?   -1.2   0.0       1.2   3.6e+03       2      33 ..      63      94 ..      63      95 .. 0.82
   3 ?    0.9   0.0      0.25   7.6e+02       2      19 ..      97     114 ..      96     114 .. 0.86
   4 ?   -1.1   0.1       1.1   3.3e+03       1      20 [.     299     318 ..     299     319 .. 0.83
   5 ?    6.8   0.0    0.0034        10       5      33 ..     373     402 ..     371     403 .. 0.87

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.77
      TPR_17  8 ldPnnadaynn 18
                 dP+n++ +  
  EEA21856.1 25 EDPDNFETWEK 35
                59*****9976 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 1.2
      TPR_17  2 ylkaleldPnnadaynnLAelllknGdlmtAr 33
                y ++l++ P  +  +  +A l  ++ +++ A+
  EEA21856.1 63 YDRFLAKFPLLFGYWKKYADLEFSIAGTEAAE 94
                8999*****99999999999887776666665 PP

  == domain 3  score: 0.9 bits;  conditional E-value: 0.25
      TPR_17   2 ylkaleldPnnadaynnL 19 
                 y++ ++  P+++d+++n+
  EEA21856.1  97 YERGVASIPTSVDLWTNY 114
                 78888888********97 PP

  == domain 4  score: -1.1 bits;  conditional E-value: 1.1
      TPR_17   1 lylkaleldPnnadaynnLA 20 
                 ly+++l  +  + +++  +A
  EEA21856.1 299 LYERCLVTCAHYDEFWLRYA 318
                 7*****99888888888887 PP

  == domain 5  score: 6.8 bits;  conditional E-value: 0.0034
      TPR_17   5 aleld.PnnadaynnLAelllknGdlmtAr 33 
                 a+ l+ Pn+++    LA+l ++ G+l++A+
  EEA21856.1 373 AILLNlPNHVETIVSLANLSRRHGKLEDAI 402
                 555555**********************97 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.1      0.45   1.3e+03      51      73 ..     317     340 ..     276     342 .. 0.65
   2 ?   10.0   0.0   0.00027      0.81       8      70 ..     353     407 ..     348     412 .. 0.84

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.45
      TPR_12  51 Lgrlyral.gryeeAlelleeala 73 
                 ++r+ +a+ g+ ee ++++++a  
  EEA21856.1 317 YARWMSAQpGKEEEVRNIYQRAST 340
                 566665444777888888888765 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00027
      TPR_12   8 nlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlellee 70 
                 ++a ++   +r d A++++e+ l        p+h +t+ +l nL+r +   g++e+A++ ++ 
  EEA21856.1 353 HYAYFEEMSERVDVARDIHEAILLNL-----PNHVETIVSLANLSRRH---GKLEDAIDVYKS 407
                 57777888899999999999998888.....99*99999999999988...999999999986 PP

>> Gla  Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.4       3.9   1.2e+04      36      40 ..      76      80 ..      75      81 .. 0.87
   2 ?   -1.4   0.1      0.92   2.7e+03      36      41 .]     148     153 ..     145     153 .. 0.83
   3 ?   -3.3   0.0       3.8   1.1e+04      28      40 ..     271     283 ..     268     284 .. 0.74
   4 ?   -1.0   0.1      0.71   2.1e+03      33      40 ..     310     317 ..     307     318 .. 0.83
   5 ?   -2.0   0.1       1.5   4.4e+03      21      29 ..     329     337 ..     327     340 .. 0.82
   6 ?    9.2   0.0   0.00046       1.4      19      40 ..     436     461 ..     434     462 .. 0.86

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 3.9
                TSSSS CS
         Gla 36 FWkkY 40
                +WkkY
  EEA21856.1 76 YWKKY 80
                8**** PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.92
                 TSSSSX CS
         Gla  36 FWkkYt 41 
                 FW kY+
  EEA21856.1 148 FWDKYI 153
                 *****5 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 3.8
                 -SSCTTTTTSSSS CS
         Gla  28 eddektkeFWkkY 40 
                 e de + + Wk+Y
  EEA21856.1 271 ELDEGQLANWKRY 283
                 6677788889999 PP

  == domain 4  score: -1.0 bits;  conditional E-value: 0.71
                 TTTTSSSS CS
         Gla  33 tkeFWkkY 40 
                  +eFW +Y
  EEA21856.1 310 YDEFWLRY 317
                 589***99 PP

  == domain 5  score: -2.0 bits;  conditional E-value: 1.5
                 SHHHHSC-S CS
         Gla  21 EEArEiFed 29 
                 EE+r i++ 
  EEA21856.1 329 EEVRNIYQR 337
                 9*****986 PP

  == domain 6  score: 9.2 bits;  conditional E-value: 0.00046
                 SSSHHHHSC-SSCTT....TTTSSSS CS
         Gla  19 syEEArEiFeddekt....keFWkkY 40 
                 s E Ar +F+++++t    ++FW++Y
  EEA21856.1 436 SSEDARQVFQNNQQTcldsRAFWTRY 461
                 6799********998666679****9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (587 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       629  (0.0350828); expected 358.6 (0.02)
Passed bias filter:                      515  (0.0287244); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.62u 0.28s 00:00:00.90 Elapsed: 00:00:00.44
# Mc/sec: 4017.32
//
Query:       EEA21857.1  [L=254]
Description: 60S ribosomal protein L25, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.2e-46  158.2  12.1    4.3e-46  156.4  12.1    1.9  1  Mitoc_mL59  Mitochondrial ribosomal protein mL59
  ------ inclusion threshold ------
        0.2   11.6   1.4       0.34   10.9   0.2    1.9  2  HetR_C      Heterocyst differentiation regulator C-terminal H


Domain annotation for each model (and alignments):
>> Mitoc_mL59  Mitochondrial ribosomal protein mL59
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  156.4  12.1   4.9e-50   4.3e-46       2     129 .]      50     239 ..      49     239 .. 0.99

  Alignments for each domain:
  == domain 1  score: 156.4 bits;  conditional E-value: 4.9e-50
  Mitoc_mL59   2 alkrffareppsalsasaaka...............................................................arlpnPflptknpkt 37 
                 +l++ffa++pp+++sa+ a+a                                                               +++pnPflp+ +p+ 
  EEA21857.1  50 RLRNFFAKYPPQHYSAAVAPAsrlaapanavsnsnnpntsseeidlsslspedlptpytpnrdakgnkrnptawsaskailyndSEYPNPFLPQPSPNG 148
                 79**************99999***************************************************************99************* PP

  Mitoc_mL59  38 grWapPkySlRrqaeLvKaAkksgveellPpgpKstkfkeeraverglrvkgtagkkkmfkGhkwERtkeerlekrrkaledmpkrirewke 129
                 ++W+ Pky lR+qa+L+K+Akk+gve+llP+++Kst fke+r +ergl++kgt g ++++kGhkwERt+e+rle+r+ka+++mp++ir+wk+
  EEA21857.1 149 KKWRSPKYGLRQQADLIKMAKKYGVEQLLPTSRKSTVFKETRLAERGLAIKGT-GIGQKVKGHKWERTMETRLEERKKAMMEMPELIRQWKQ 239
                 *****************************************************.*************************************7 PP

>> HetR_C  Heterocyst differentiation regulator C-terminal Hood domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.1      0.22     2e+03      18      32 ..       8      22 ..       2      33 .. 0.67
   2 ?   10.9   0.2   3.8e-05      0.34      38      66 ..     217     245 ..     206     249 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.22
      HetR_C 18 rlmrdwaerkpkvlr 32
                rl+r+ a r   ++ 
  EEA21857.1  8 RLVRNMARRTMTTMA 22
                777777777766664 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 3.8e-05
      HetR_C  38 dippekleqaleeldeiirewadkyhqeg 66 
                 +   e+ ++a+ e+ e+ir+w  + h  g
  EEA21857.1 217 ETRLEERKKAMMEMPELIRQWKQRGHGRG 245
                 556678899***************99766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (254 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       678  (0.0378158); expected 358.6 (0.02)
Passed bias filter:                      462  (0.0257683); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1688.55
//
Query:       EEA21858.1  [L=881]
Description: molybdenum cofactor sulfurase protein (HxB), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.8e-32  111.5   0.0    5.1e-32  110.6   0.0    1.5  1  MOSC         MOSC domain
    8.7e-25   87.4   0.0    5.8e-24   84.7   0.0    2.1  1  Aminotran_5  Aminotransferase class-V
    1.6e-23   82.8   0.0    3.5e-23   81.8   0.0    1.6  1  MOSC_N       MOSC N-terminal beta barrel domain


Domain annotation for each model (and alignments):
>> MOSC  MOSC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.6   0.0   8.6e-36   5.1e-32       3     130 ..     692     873 ..     690     874 .. 0.96

  Alignments for each domain:
  == domain 1  score: 110.6 bits;  conditional E-value: 8.6e-36
                 X---GGGGSEEEEETHHHHHHHHHS..GGG..............GG-STTTT--SEEES-.............................-TTT-BTT-E CS
        MOSC   3 kihggdekavllisresldalneelkegrs..............veldpgrfreNivvggaaa......................feEdtwkelrigdr 65 
                 +i +++e+++llisr+s+++lne++ke+                + +++++fr+Nivv+ + +                      + Edtw++++ig++
  EEA21858.1 692 PILLSNESPILLISRSSVNRLNEQIKENSTtttisplsstnpntKTVAANVFRANIVVAENLPshshpqhsslpisstsspfeqpYIEDTWSSITIGQK 790
                 6899*********************88877**************9*************6655569********************************99 PP

                 ...EEETT................EE----THHHHHTTHHHHHHHHT---EEEEEEE-E....................EEETTS-E CS
        MOSC  66 ..rfrlggacsRcqmvnvdqetgarprepcktlakfrrvdkrvkgkgrfGvylrvleeg....................tvrvGdev 130
                   rf+++gacsRcqmv+vdq t+++++ep++tlak+rrv     gk++fG++l + ++                     tv+vGd+v
  EEA21858.1 791 qlRFDVLGACSRCQMVCVDQMTAEKREEPLSTLAKTRRVG----GKVIFGRHLGLSASNddleydqdegedeaeeiserTVMVGDTV 873
                 999***********************************98....***********99999*************************99 PP

>> Aminotran_5  Aminotransferase class-V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.7   0.0   9.7e-28   5.8e-24       2     370 ..      33     458 ..      32     459 .. 0.73

  Alignments for each domain:
  == domain 1  score: 84.7 bits;  conditional E-value: 9.7e-28
                  EEBTTTS----HHHHHHHHHHHH.CTCCSSSSSSSHHHHHHHHHHHHHHHHHHHHHT-STG.GGEEEESSHHHHHHHHHHHCCCC.....-TTTSEEE CS
  Aminotran_5   2 yldsaAttqkpqeVldalqeyyt.dynanvhrsvhhlgkeatkaveearekvaelinaese.eeiiftsGtteainlvalslars.....lkpgdeiv 92 
                  yld a+tt   ++ ++++++ +t +  +n+h++  + ++ +++ +e++r k  +++na+ + ++++f+ ++t +i+lva sl++       ++++ + 
   EEA21858.1  33 YLDHAGTTLYAKSLIEKYSQDLTsNLFGNPHSASAS-SQITSNRIEDIRLKALRFFNADPDvYDLVFVPNATAGIKLVAESLRDFrsssfGDRQRGFW 129
                  9****************9887752789***987655.555899***************865489******************9877756434455677 PP

                  EE.TTSHGGGTHHHHHHHHHHTEEEEEEEBETTSCBEGGGHHHH--TTEEEEEEESBETTTTEB--HHHHHHH..HHHTT-EEEEE-TTTTTTS---H CS
  Aminotran_5  93 vt.eaehhanlvpwqelakrtgakvkvipldeegeldldelekllnektklvaithvsnvtGtiqpveeigkl..akkkgalvlvDaaqavghipidv 187
                  ++ +++ h  lv  + la + g +   ++ d +   ++ +  ++ ++ t+l a+ + sn+ G  +p++  +++  a k++ ++l+Daa+ v   p+d+
   EEA21858.1 130 YGyHVDSHTSLVGVRTLA-DFGNRC--FSTD-NEVRQWVDSLNTNDDSTRLFAYPAQSNMNGQRFPLNWCNQIrtAGKQNTFTLLDAASLVSTSPLDL 223
                  763689999999999999.557766..4443.34444444556679********************98665441155579****************** PP

                  HHHTE..SEEEEETTTTTSSTT-EEEEEEHHHHHTS...SS.STTSEEEEET.TEEE...EHCTTGGGS.SS--HHHHHHHHHHHHHHHCH..HHHHH CS
  Aminotran_5 188 kklgv..DflafsghKllgPtGiGvlyvrkellekl.eplllggemveevsl.eett...faeapskfeaGTpnvagiiglgaaleyleei..gleai 276
                  ++ +v  Df+++s  K++g + +G+l+vrke  + + +  ++gg++ve v++ +e+    +++   ++e GT +  +ii+l+ a++  e++   +++i
   EEA21858.1 224 SDPQVcpDFVVLSFYKIFGFPDLGALIVRKESGHIFnHRQYFGGGTVEMVTVgNEWYarkQSSIHDQLEDGTLPFHNIIALESAFQVHERLygSIANI 321
                  *999889***************************99666789**********9999833344455689********************7643389*** PP

                  HHHHHHHHHHHHHHHCTSTT......EEE...ES.-..B-CTCBSEEEEEETTCSH.....HHHHHHHHHTTEEEEEE-TTT........HHHHHHTT CS
  Aminotran_5 277 ekhekelaeyllerlkslpg......vrl...ygpd..kaerrasivsfnfkgvha.....edvatlLdeegIavrsGhhca........qplmkrla 350
                   +h + l ++l +rl+s+++      + +    g++  +   +  i+++n+ + +      +++++l   + I++rsG  c                 
   EEA21858.1 322 SNHTAFLVKQLFDRLSSIKHangkpvCHFylsSGCSyeDRSSQGPIIALNLLDSNGdwvgkSEIEKLASVKSIHIRSGTLCNpggtasllG------- 412
                  *****************98722222233322222330033334445555553333333554555555555577777777776443332221....... PP

                  .S..........................-EEEEE--TTS-HHHHHH CS
  Aminotran_5 351 le..........................gtvRaSlyiynteeevdr 370
                  l+                          g++R+Sl+  +++ ++dr
   EEA21858.1 413 LSneemeanykagqrcgdendimqgkptGALRLSLGPMTSSRDIDR 458
                  2222333445555566666666666666666666666666666665 PP

>> MOSC_N  MOSC N-terminal beta barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.8   0.0   5.9e-27   3.5e-23       3     120 .]     491     631 ..     489     631 .. 0.87

  Alignments for each domain:
  == domain 1  score: 81.8 bits;  conditional E-value: 5.9e-27
      MOSC_N   3 rvssLyvyPiKsckgvslseae...vtaaGllalDReflvvd.edGkfltqrrePrlalirteldeedglLtltap...grkdlevsla.......kak 87 
                 +v+sL vyPiKsc g+ ++      v+++Gl a+DRe+++v+  +G++l q+r+P++ali++ ld e+glL +t +   gr +l ++l        +++
  EEA21858.1 491 YVESLCVYPIKSCSGFAIPPGVvwkVRPEGL-AWDREWCIVHqGTGTALSQKRYPHMALIKPILDFEKGLLCITGDsatGRRQLDIPLSrddprlvTTE 588
                 79*****************9876779****8.6*********99*****************************976677*********98777654333 PP

      MOSC_N  88 asleevsvlelsasgldegd..........evakwlsdfLgkp 120
                  +++  +  + ++++l +gd          ev++++sd+Lg+p
  EEA21858.1 589 MTRSCQNSASVRKPSLICGDrvviqvytssEVSAFFSDLLGVP 631
                 44444445567889999999********************975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (881 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       379  (0.0211389); expected 358.6 (0.02)
Passed bias filter:                      315  (0.0175693); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.64u 0.28s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 5906.08
//
Query:       EEA21859.1  [L=198]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
      0.028   14.4  20.3       0.04   14.0  20.3    1.2  1  MARVEL     Membrane-associating domain
       0.69   10.6   0.1       0.69   10.6   0.1    2.7  3  SelK_SelG  Selenoprotein SelK_SelG
        7.1    4.8  13.8        9.4    4.4  13.8    1.1  1  DUF2070    Predicted membrane protein (DUF2070)


Domain annotation for each model (and alignments):
>> MARVEL  Membrane-associating domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0  20.3   6.6e-06      0.04       7     144 .]       8     154 ..       5     154 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 6.6e-06
      MARVEL   7 gilrilqlvfaiiilgliasliakldqllgspssalnfavfvavfsflyalfllvlylfknsaftsilwplidlivdalaallwlvafialaaglrdis 105
                 +++r+ ++vf i i+g+ a+++     ++ ++++ ++ ++ v ++   +a+f+++ ++++  +   ++  +++ ++d  +++  l+a++     + + s
  EEA21859.1   8 IFWRLTEIVFLIPIIGMLAYFV----NGFINANQLTPAYILVLFIVSTIAVFWCIDTILR--FGSTRRSAIFVAFLD-MCFFGALIAGVYQLRFIAGAS 99 
                 689*******************....4455556666666666666667788888887763..444455555555555.455556888899999999999 PP

      MARVEL 106 ca.............fe...snqysasltvrcgqaqaavafgflavllfaasavl 144
                 c+             f    ++ + ++ ++ c+ ++a+ a+g + v++f+++a++
  EEA21859.1 100 CTswsnstssvslgpFGsivYTGETPNFNKTCSMLKASFAMGIMEVVFFTITAFF 154
                 9999999988888772257888999****************************98 PP

>> SelK_SelG  Selenoprotein SelK_SelG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.2      0.17   9.9e+02      16      43 ..      10      36 ..       5      43 .. 0.81
   2 ?   -1.6   0.1      0.71   4.2e+03      28      47 ..      48      69 ..      28      74 .. 0.68
   3 ?   10.6   0.1   0.00012      0.69      13      68 ..     131     183 ..     119     196 .. 0.68

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.17
   SelK_SelG 16 wrlsiitdffwgivnfivlFfqtLlspd 43
                wrl  i+ f++ i+ ++ +F++ +++ +
  EEA21859.1 10 WRLTEIV-FLIPIIGMLAYFVNGFINAN 36
                7777776.67789999999999999876 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.71
   SelK_SelG 28 ivnfivlF..fqtLlspdlskn 47
                iv+ i +F  ++t+l++ ++++
  EEA21859.1 48 IVSTIAVFwcIDTILRFGSTRR 69
                4455555544677777777765 PP

  == domain 3  score: 10.6 bits;  conditional E-value: 0.00012
   SelK_SelG  13 rspwrlsiitdffwgivnfivlFfqtLlspdlskns.nssssskkrr....ggggggggGp 68 
                  s+ + s+ ++++  ++  i+ Ff+ L++    ++  +++  +++++    g         
  EEA21859.1 131 CSMLKASFAMGIMEVVFFTITAFFALLIHRHHHDTVvKETVVRRRSHssrrG--------H 183
                 478888999999999999***********99999997776666666533222........2 PP

>> DUF2070  Predicted membrane protein (DUF2070)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4  13.8    0.0016       9.4      18     159 ..      12     158 ..       8     163 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.0016
     DUF2070  18 llliillalligllaflssk.....lfgillfglpalvaflltlpvlrilggrltykrs.lflalltelivviisllaillsall.qalvllalvlsla 109
                 l+ i++l+ +ig+la+ ++        +  ++++ ++v+++++ ++++++ +   ++rs +f+a+l + ++ +++   + l   + +  +  ++  s +
  EEA21859.1  12 LTEIVFLIPIIGMLAYFVNGfinanQLTPAYILVLFIVSTIAVFWCIDTILRFGSTRRSaIFVAFLDMCFFGALIAGVYQLR--FiAGASCTSWSNSTS 108
                 5668899999999999988889999777788888899999999999999977766777768888888888888444444444..446778888888899 PP

     DUF2070 110 lvfalrllvlvavsdesllkavlpaliqpllailllvlyfspesflllll 159
                 +v   ++  +v ++++  ++ +   l  ++++ ++ v++f+ + f+ ll+
  EEA21859.1 109 SVSLGPFGSIVYTGETPNFNKTCSMLKASFAMGIMEVVFFTITAFFALLI 158
                 99999999999999999999999999999999999999976666665554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (198 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       998  (0.055664); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 1297.50
//
Query:       EEA21860.1  [L=424]
Description: PAP2 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    4.3e-28   97.8   0.5    4.3e-28   97.8   0.5    1.6  2  PAP2       PAP2 superfamily
  ------ inclusion threshold ------
      0.013   15.4   0.1        4.1    7.4   0.0    2.3  2  SafA       Two-component-system connector protein
      0.022   14.7   0.0      0.043   13.8   0.0    1.4  1  SLATT_1    SMODS and SLOG-associating 2TM effector domain 1
       0.14   12.5   3.5       0.29   11.5   3.5    1.5  1  Luteo_Vpg  Luteovirus putative VPg genome linked protein


Domain annotation for each model (and alignments):
>> PAP2  PAP2 superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.1       2.4   1.1e+04      84     105 ..      71      92 ..      61      93 .. 0.61
   2 !   97.8   0.5   9.6e-32   4.3e-28       3     132 ..     129     276 ..     127     279 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 2.4
        PAP2  84 lvllalillllavlvalsRlyl 105
                   ll+ i+  l+v + ++ +++
  EEA21860.1  71 EALLISIASPLVVIILYTLVID 92 
                 4566666666666666666665 PP

  == domain 2  score: 97.8 bits;  conditional E-value: 9.6e-32
        PAP2   3 lalllalalaalltsvlKdlvgrpRPfflaeetkldtqvstletses..............keakesfPSgHsafafalalllalllrrkrkkig.... 83 
                 l l l+ +la ++t++lK+++g+pRP+ ++++++  ++++                     k++++s+PSgHs+ +fa++++l+l+l+ k + ++    
  EEA21860.1 129 LGLFLSQGLAFVTTQILKNACGKPRPDLIDRCQPAPGSHDL-PVF-GlsnstictgdpvliKDGFRSWPSGHSSSSFAGLFYLSLYLGGKMHIMDnrge 225
                 6788889999999********************99887553.222.24679************************************************ PP

        PAP2  84 ..lvllalillllavlvalsRlylgvHflsDvlaGlliGialaalayrlvq 132
                   +++++++++l+a+l+a++R+ + +H+++Dv++G l+G+++a+++yr+++
  EEA21860.1 226 vwKTIIVMVPILAATLIAVTRIMDARHHPFDVITGSLLGVFTAWASYRQYF 276
                 ************************************************997 PP

>> SafA  Two-component-system connector protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.0   0.00092       4.1       5      39 ..      62      97 ..      59     112 .. 0.83
   2 ?    5.6   0.0    0.0034        15      13      41 ..     220     249 ..     214     251 .. 0.74

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.00092
        SafA  5 tvknkitqrdn.ykeimsvivvvllltltliaifsa 39
                +vk++it ++     i s +vv++l tl +  +fs 
  EEA21860.1 62 AVKERITIQEAlLISIASPLVVIILYTLVIDGLFSH 97
                589999966551679**************9999985 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0034
        SafA  13 rdnykeims.vivvvllltltliaifsaid 41 
                  dn  e+   +iv+v +l+ tlia+   +d
  EEA21860.1 220 MDNRGEVWKtIIVMVPILAATLIAVTRIMD 249
                 5777777651567788********976665 PP

>> SLATT_1  SMODS and SLOG-associating 2TM effector domain 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   9.5e-06     0.043      16      76 ..     216     277 ..     211     281 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 9.5e-06
     SLATT_1  16 kaeeneraakrwrlllillellalllaalrafgelsvdlvgvla.avaaallaWlelkqyee 76 
                 k++ ++++ ++w+++++++ +la++l+a+  + ++  ++++v++ ++ + ++aW+ ++qy +
  EEA21860.1 216 KMHIMDNRGEVWKTIIVMVPILAATLIAVTRIMDARHHPFDVITgSLLGVFTAWASYRQYFP 277
                 667788999*****************9999777788878888764789999********965 PP

>> Luteo_Vpg  Luteovirus putative VPg genome linked protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   3.5   6.5e-05      0.29      13      99 ..     329     408 ..     322     413 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 6.5e-05
   Luteo_Vpg  13 sylqlttlkatPkevsnsarvyrtvrrsrteysrPtivirsqvselsssarPlPirqvlsllsstPiakyqPsvatlissklaraaP 99 
                  ++q   l++ P++ ++ + vyr+ rr +  ys+      s + e+     P   r+   l  st  ++ qP+ +t   s+ + a+P
  EEA21860.1 329 DVSQEFSLHPQPQQSAPRGAVYRNKRRNHDGYSSSSSEDVSEAFEM---NTP---RERGRLNVSTATTSRQPYDTTYY-SPGRSASP 408
                 4789999**************************9765544444444...445...66667777888888888876654.45555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (424 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       567  (0.0316247); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 2925.22
//
Query:       EEA21861.1  [L=286]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (286 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       964  (0.0537676); expected 358.6 (0.02)
Passed bias filter:                      449  (0.0250432); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 1961.34
//
Query:       EEA21862.1  [L=565]
Description: nucleolar GTPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      3e-50  169.7   0.1    4.7e-50  169.1   0.1    1.3  1  NGP1NT       NGP1NT (NUC091) domain
    9.3e-18   64.4   1.0      1e-13   51.3   0.0    3.2  3  MMR_HSR1     50S ribosome-binding GTPase
    5.4e-06   26.0   0.0      8e-05   22.2   0.0    2.2  2  FeoB_N       Ferrous iron transport protein B
    0.00019   21.4   0.0    0.00043   20.2   0.0    1.6  1  RsgA_GTPase  RsgA GTPase
    0.00077   19.0   0.1       0.16   11.4   0.0    2.3  2  Arf          ADP-ribosylation factor family
     0.0013   18.8   0.1        1.2    9.2   0.0    3.5  3  Dynamin_N    Dynamin family
     0.0088   15.5  18.4     0.0088   15.5  18.4    1.5  2  SDA1         SDA1
  ------ inclusion threshold ------
        0.1   12.8   0.0         25    5.1   0.0    2.6  2  Roc          Ras of Complex, Roc, domain of DAPkinase


Domain annotation for each model (and alignments):
>> NGP1NT  NGP1NT (NUC091) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  169.1   0.1   2.1e-53   4.7e-50       1     130 []      43     177 ..      43     177 .. 0.97

  Alignments for each domain:
  == domain 1  score: 169.1 bits;  conditional E-value: 2.1e-53
      NGP1NT   1 mykegkakrdkkGkiikaaalqskeasksariepdrrWFgntrvisqeaLekfreeleekvkdpysvllkrnklPmsLledkakk......kkvkllet 93 
                 m+k+gkak+d++G+i+kaa++qs+e  ++ariep+r+WFgntrvisqeaL++fre+++e+++dpy+vllk+nklPmsL++d ++       ++++++et
  EEA21862.1  43 MFKDGKAKHDAQGNIVKAASYQSTEL-PNARIEPNRKWFGNTRVISQEALTSFREAVAERAADPYQVLLKTNKLPMSLIRDGQELnglkqhRAKMTIET 140
                 99************************.******************************************************9998899998888999** PP

      NGP1NT  94 esfeetFgpkaqrkrpklevsdleelakkaeekaeky 130
                 ++f +tFgpkaqrkr+kl+v++le+la ++ +++++y
  EEA21862.1 141 SPFGDTFGPKAQRKRVKLDVGSLEDLAGESVKMHDSY 177
                 *****************************99999987 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   0.0   0.00038      0.85      66     114 .]     218     268 ..     161     268 .. 0.76
   2 !   51.3   0.0   4.6e-17     1e-13       2      66 ..     325     390 ..     324     424 .. 0.82
   3 ?   -0.7   0.4      0.66   1.5e+03      61      94 ..     522     552 ..     495     563 .. 0.62

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00038
                 HHHHHHHHHC.TSEEEEEEETT..TTCSHHHHHHHHHHHHH..TTSEEEEEEES CS
    MMR_HSR1  66 lgkaflalee.adlillvvdas..eeklkpldeeleellee..akkplilvlnk 114
                 + +++ ++++ +d++++v+da+  +       +++e++++e   +k li+vlnk
  EEA21862.1 218 IWNELYKVIDsSDVVIHVLDARdpN---GTRCRSIEKYIREeaPHKHLIFVLNK 268
                 444444555548********88431...3344777787776667888999*998 PP

  == domain 2  score: 51.3 bits;  conditional E-value: 4.6e-17
                 EEEEESTTSSHHHHHHHHHTS.TEEESSSTTSSSSEEEEEEEETTEEEEEEECGGCSS...HHHHHHHH CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltge.kaivsdkpgtTrdinegrvklkgkeielvDtpGlie...gaseekgl 66 
                 v+++G+pN+GKS++in+l ++ ++ v+ +pg T+  +++++    k+i+l+D+pG++    ++see  l
  EEA21862.1 325 VGFIGYPNTGKSSIINTLRNKkVCTVAPIPGETKVWQYITLM---KRIYLIDCPGVVPpnqNDSEEDIL 390
                 89******************9567*****************8...68********87433333333334 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 0.66
                 HHHHHHHHHHHHHHCTSEEEEEEETTTTCSHHHH CS
    MMR_HSR1  61 seekglgkaflaleeadlillvvdaseeklkpld 94 
                 +++ ++ ++f + +e+d  ++v d   +  +++d
  EEA21862.1 522 EDDSNEFEEFDDDDESDGGIHVSDDD-D--DDED 552
                 2233566667778889*******933.3..2233 PP

>> FeoB_N  Ferrous iron transport protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0     0.098   2.2e+02      77     122 ..     227     276 ..     215     303 .. 0.71
   2 !   22.2   0.0   3.6e-08     8e-05       2      71 ..     324     391 ..     323     436 .. 0.80

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.098
                 TSSSEEEEEEEGGGHH..HHHHHHHHHHHTT..SSEEEEEETHHHHHHTT CS
      FeoB_N  77 eepdvvvnvvdatnle..rnLyLtlqllelg..vpvvlalnmideaekkg 122
                 ++ dvv++v+da   +  r   +   + e    ++++ +ln++d + +k 
  EEA21862.1 227 DSSDVVIHVLDARDPNgtRCRSIEKYIREEAphKHLIFVLNKCDLVPTKV 276
                 67899******986542255555555555432277888888888876665 PP

  == domain 2  score: 22.2 bits;  conditional E-value: 3.6e-08
                 EEEEEESTTSSHHHHHHHHHTTS.EEEEESTTSSSEEEEEEEEETTEEEEEEE----SSSSSSSHHHHHHH CS
      FeoB_N   2 tvalvGnpnvGkttlfnaltgak.qkvgNwpGvtvekkegklklkgkeveivDlPGiYslsayseeekvar 71 
                 +v ++G pn+Gk++++n+l ++k  +v+  pG t   +  +l    k++ ++D PG+   ++  +ee +  
  EEA21862.1 324 SVGFIGYPNTGKSSIINTLRNKKvCTVAPIPGETKVWQYITL---MKRIYLIDCPGVVPPNQNDSEEDILL 391
                 6789***************99874589999998755555544...59**********98887777776654 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.0   1.9e-07   0.00043      31     161 ..     245     377 ..     223     382 .. 0.66

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 1.9e-07
                  -HHHHHHHHHHHHHTT-EEEEEEE-GGG--HHH...HHHHHHHHHHHTTSEEEE--TT.TH......TTHHHHHHHCTTSEEEEECSTTSSHHHHHHH CS
  RsgA_GTPase  31 slnlldrfLvlaeekgiepvivlnKiDlleeee...eleelkeelealgyevllvsak.tk......egleelkellkdktsvlvGqSGvGKStLina 118
                  + + +++++   e+ + +++ vlnK+Dl+ ++     +++l++++ +l ++  + ++  ++      +++++l++  k+  + ++G    GKS++in+
   EEA21862.1 245 RCRSIEKYIR-EEAPHKHLIFVLNKCDLVPTKVaaaWVRHLSKDYPTLAFHASINNSFgKGsliqllRQFSALHSDRKQISVGFIGYPNTGKSSIINT 341
                  4566677654.3666778999********999955556666666666665554444331331111112223333333333445999999********* PP

                  HCTT-----S--------------SEEEEEETTTEEEESS-SS CS
  RsgA_GTPase 119 llpelelktgevseklgrGkhTTtavellelaegglliDtPGf 161
                  l++++   ++ +  +       T+  + + l +  +liD PG+
   EEA21862.1 342 LRNKKVCTVAPIPGE-------TKVWQYITLMKRIYLIDCPGV 377
                  ****99999999987.......556666666667777777776 PP

>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.1   0.0    0.0061        14      71     131 ..     215     275 ..     209     292 .. 0.70
   2 !   11.4   0.0   7.2e-05      0.16       4      47 ..     312     355 ..     309     367 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0061
                 GGGGGGGGCTTE...SEEEEEEETT-CTTHHHHHHHHHHHCTSGCCTTSEEEEEEE-TTSTTSS CS
         Arf  71 lRplWknYfekt...davifvvDsadreRleeakeeLkalleeeelkevallvlaNKqDlpeal 131
                  +++W++ ++ +   d+vi+v+D+ d +      + +++ ++ee  ++ +l+ + NK Dl  + 
  EEA21862.1 215 SKRIWNELYKVIdssDVVIHVLDARDPNGT--RCRSIEKYIREEAPHK-HLIFVLNKCDLVPTK 275
                 578999988765222689999999998853..3456778887766555.6677789*9997654 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 7.2e-05
                 HHHGGTT.TTEEEEEEEESTTSSHHHHHHHHHHSSCEECSSSSS CS
         Arf   4 ilaklklkkkelrilllGLDnaGKtTilkklkleelvttvPTig 47 
                  ++ l++ +k++ + ++G  n+GK+ i++ l+++++ t+ P  g
  EEA21862.1 312 QFSALHSDRKQISVGFIGYPNTGKSSIINTLRNKKVCTVAPIPG 355
                 678899999*****************************999766 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0     0.075   1.7e+02     119     167 ..     215     268 ..     200     269 .. 0.72
   2 !    9.2   0.0   0.00053       1.2       1      30 [.     325     354 ..     325     361 .. 0.87
   3 ?    3.1   0.0     0.039        87      97     119 ..     363     385 ..     355     407 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.075
                 S....HHHHHHHSTTEEEEEEEETTS-CCC-CHHHHHHHHSTTBTT..EEEEEE- CS
   Dynamin_N 119 q....elvkeyikkadiilavtsanhdlsnsealflarevdpkgkr..tivvltk 167
                      + + + i+++d++++v++a      ++ + +++ ++++      i+vl+k
  EEA21862.1 215 SkriwNELYKVIDSSDVVIHVLDARDPNG-TRCRSIEKYIREEAPHkhLIFVLNK 268
                 14455788999*************98665.6667777777766655557888887 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00053
                 EEEEEBTTTTHHHHHHHHHTS--S---SSS CS
   Dynamin_N   1 iavvGsqSsGKSSvlnaLlgedilprgpnp 30 
                 + ++G  + GKSS++n L  +++  + p+p
  EEA21862.1 325 VGFIGYPNTGKSSIINTLRNKKVCTVAPIP 354
                 5689999**************999988877 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.039
                 ETTS-SEEEEE---B-SSSGTTS CS
   Dynamin_N  97 sllvkgltlvDlPGldsvnkrdq 119
                   l k++ l+D PG+   n++d 
  EEA21862.1 363 ITLMKRIYLIDCPGVVPPNQNDS 385
                 56788999********9999986 PP

>> SDA1  SDA1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.7       1.6   3.5e+03     207     221 ..      82      96 ..       5     199 .. 0.51
   2 !   15.5  18.4   3.9e-06    0.0088      58     144 ..     475     560 ..     458     565 .] 0.54

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 1.6
        SDA1 207 ttrILTpaDFaklke 221
                 +tr+++++ +   +e
  EEA21862.1  82 NTRVISQEALTSFRE 96 
                 334444443333333 PP

  == domain 2  score: 15.5 bits;  conditional E-value: 3.9e-06
        SDA1  58 akkfGeeevaegieGle..Llekwkeeekkekre...eeeedsddeddeedwevesdddseedseggwidvesdeeeieesdesedeeeeee 144
                 ++ + e ++ e+ieG e  L e  k+ +++   +    +++ ++++++++++e e+ dd+ ++s+gg i v++d++    +de+ede+++ +
  EEA21862.1 475 PPPYTEGNEDEKIEGREgrLGEMSKKRKRDTPAAdseANDDAKSEDEEDDSNEFEEFDDD-DESDGG-IHVSDDDD----DDEDEDEDKDGD 560
                 67899999999*******555554444444433243311122222233333333333333.455555.88877766....232233332222 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   0.0     0.012        28      78     120 .]     227     271 ..     215     271 .. 0.82
   2 ?    5.1   0.0     0.011        25       4      24 ..     327     347 ..     324     363 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.012
                 CTSCEEEEEEEGHHH..HCHHHHHHHHHHHCSSS-EEEEEE-TTT CS
         Roc  78 reaalailvydsrss..enlkeWlkelkkvagkspvilvgnkiDl 120
                  +++++i v+d+r+   ++ ++  k ++++a+++ +i+v nk+Dl
  EEA21862.1 227 DSSDVVIHVLDARDPngTRCRSIEKYIREEAPHKHLIFVLNKCDL 271
                 5678899999987542267788889999***************95 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.011
                 EESSTTSSHHHHHHCHCT-CC CS
         Roc   4 lvGdsgvGKtsllkrfvedkf 24 
                 ++G  ++GK+s+++ + ++k+
  EEA21862.1 327 FIGYPNTGKSSIINTLRNKKV 347
                 89*************999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (565 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       766  (0.0427241); expected 358.6 (0.02)
Passed bias filter:                      490  (0.02733); expected 358.6 (0.02)
Passed Vit filter:                        87  (0.00485247); expected 17.9 (0.001)
Passed Fwd filter:                        21  (0.00117129); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.67u 0.30s 00:00:00.97 Elapsed: 00:00:00.43
# Mc/sec: 3901.42
//
Query:       EEA21863.1  [L=731]
Description: protein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      6e-38  130.7   0.0    1.2e-37  129.7   0.0    1.4  1  Pkinase          Protein kinase domain
      2e-27   96.1   0.0    3.3e-27   95.4   0.0    1.3  1  Pkinase_Tyr      Protein tyrosine kinase
    0.00036   20.0   0.0    0.00058   19.3   0.0    1.3  1  Kinase-like      Kinase-like
  ------ inclusion threshold ------
      0.013   14.9   0.0      0.025   13.9   0.0    1.4  1  Kdo              Lipopolysaccharide kinase (Kdo/WaaP) family
      0.028   13.4   0.0      0.043   12.8   0.0    1.1  1  Pox_ser-thr_kin  Poxvirus serine/threonine protein kinase
      0.048   13.6   0.3       0.78    9.6   0.3    2.5  1  APH              Phosphotransferase enzyme family
      0.053   12.3   0.3        0.1   11.3   0.0    1.5  2  Pkinase_fungal   Fungal protein kinase


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  129.7   0.0   4.6e-41   1.2e-37       2     259 ..     159     469 ..     158     472 .. 0.85

  Alignments for each domain:
  == domain 1  score: 129.7 bits;  conditional E-value: 4.6e-41
                 EEEEEEEEESSEEEEEEEETTTT...EEEEEEEEECHCHCHHHHHHHHHHHHHHHHHSCTTB--EEEEEEE..........SSEEEEEEE--TTEBHHH CS
     Pkinase   2 ekleklGeGsfGkVykaveketg...kivAvKkikkekakkkkekkvlrEikilkklkhpnivrlyevfee..........kdelylvleyveggelad 87 
                 +++ +lG+G+ G+V+ +++  +g    ++A+K++ + ++ +  e kvl E+++l++l+h+n+v + +v+ e              +++++y++ g+l++
  EEA21863.1 159 VEEAELGRGGKGVVLLVKHMLDGvslGHFACKRVPVGDDHEWLE-KVLIEVQLLQHLSHQNLVSYRHVWLEdykisvfgpsVPCAFILQQYCNAGDLHK 256
                 67889*************99988333589********9999885.9***********************99888888886555566999********** PP

                 HHH.......HHSS--HH.......................HHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTE...EEE-SGTTSEESSSSCS CS
     Pkinase  88 lle.......rkgslsee.......................eakkiakqilegleylHskgiiHrDlKpeNiLidekge...lKitDFGlakelesssk 153
                 ++        + ++l+e+                       e+ +++k i +g+++lH++g+iHrDlKp+N L++++g+   + ++DFG ++  +   k
  EEA21863.1 257 YVVgslststTTQQLKERirrrskgqaetpdfsgprklhfeEIYSFFKDITSGIRFLHANGFIHRDLKPSNCLLHDSGQelhVLVSDFGEVQYENAVRK 355
                 9997776554333355559999999999***********************************************888888899********9999999 PP

                 BCTTTSCGGGS-HHHHTT........SCBSHHHHHHHHHHHHHHHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCT...SHH...HHHTTS-HHHHHHH CS
     Pkinase 154 ltsfvgtseYlAPEvlke........neyskkvDvWslGvilyelltgkppfsgekgkekvekeldqlekilkilg...etkeklpeaseiseeakdll 241
                  t  +gt  Y+APEvl++         +++ k+Dv+slG+il  l + + p++ + +  + ++++d+l   ++i g     +   + + ++++++  +l
  EEA21863.1 356 STGTTGTISYCAPEVLRRqfypdgpfVNFTFKSDVFSLGMILHFLCFAQLPYR-SADLMEEKEDIDELR--AEISGwkgFDDSLKRLRPDLPDKLYTIL 451
                 ****************44345555667889***********************.555555788888844..34444333445555566788******** PP

                 HHHT-SSGCCSTTHHHHH CS
     Pkinase 242 kkllkkdpkkRltaeell 259
                 ++ll+ dp+ R+ta+e+l
  EEA21863.1 452 QRLLAIDPTFRPTADEVL 469
                 ***************997 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.4   0.0   1.3e-30   3.3e-27       4     256 ..     161     469 ..     158     472 .. 0.85

  Alignments for each domain:
  == domain 1  score: 95.4 bits;  conditional E-value: 1.3e-30
                  EEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS-BTTB--EEEEEESSSS..........EEEEEE--TTEBHHHH CS
  Pkinase_Tyr   4 gkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkklkhpnivkllgvctkeep..........llivteyvkgGdLlkf 91 
                  + +lG+G  G V   +    +  +  + a K +  + ++e  e++l e++++++l+h+n+v++  v +++ +           +i+ +y++ GdL+k+
   EEA21863.1 161 EAELGRGGKGVVLLVKHM-LDGVSLGHFACKRVPVGDDHEWLEKVLIEVQLLQHLSHQNLVSYRHVWLEDYKisvfgpsvpcAFILQQYCNAGDLHKY 257
                  568999999999998888.788888999**************************************99666666777788888999************ PP

                  HHHT............................CTTTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEE...TTEEEE-STTTHEETTTSSE CS
  Pkinase_Tyr  92 Lrkk............................ekekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlse...nkvvkisDfGLardiekdde 158
                  +  +                              +kl++++++sf  ++ +G+++L+++ ++Hrdl   N+Ll++   + +v +sDfG  +     + 
   EEA21863.1 258 VVGSlststttqqlkerirrrskgqaetpdfsGPRKLHFEEIYSFFKDITSGIRFLHANGFIHRDLKPSNCLLHDsgqELHVLVSDFGEVQYE---NA 352
                  **999**************************999****************************************8665779*******76655...88 PP

                  EEETTSSTSGGGGS-HHHHHHSE........EEHHHHHHHHHHHHHHHHTTSSGTTTTSHHHH.............HHHHHHTTEES-BBTTSBHHHH CS
  Pkinase_Tyr 159 yvkkeeaklpvkWmapEslkekk........ftsksDvWsfGvllwEiftlgespypglknee.............vleklkegkrlekpekcpeely 235
                   +k+++++  + ++apE+l+++         ft ksDv+s G++l+ ++  ++ py++ + +e               + ++++ +  +  + p++ly
   EEA21863.1 353 VRKSTGTTGTISYCAPEVLRRQFypdgpfvnFTFKSDVFSLGMILHFLCF-AQLPYRSADLMEekedidelraeisGWKGFDDSLKRLR-PDLPDKLY 448
                  9999*****************999999999**************997765.99998876544423444443333222222333333334.45899999 PP

                  HHHHHHT-SSGGGS--HHHHH CS
  Pkinase_Tyr 236 elmkkcweedpeeRptfselv 256
                  +++++ ++ dp+ Rpt  e++
   EEA21863.1 449 TILQRLLAIDPTFRPTADEVL 469
                  999999999999999988875 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.0   2.3e-07   0.00058     160     284 ..     313     458 ..     309     462 .. 0.79

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 2.3e-07
  Kinase-like 160 Lqakglvhgkftvdnllldekgg...lmlggftaLvragtkvvlseve...kgfaPpEllgsrggytrknktkmthkldaWqlGlviyriwclklPlt 251
                  L+a+g +h ++++ n ll+  g+   + + +f++  ++ + v+ s+      ++  pE+l + + y     +++t+k d+  lG+   ++  ++lP  
   EEA21863.1 313 LHANGFIHRDLKPSNCLLHDSGQelhVLVSDFGEV-QYENAVRKSTGTtgtISYCAPEVLRR-QFYPDGPFVNFTFKSDVFSLGMILHFLCFAQLPYR 408
                  99****************9887444499*****96.5555566444334457899****977.66888899******************999****86 PP

  Kinase-like 252 lat.eeakeew...............kfklck.kipekvkaLlkkfLqls 284
                   a   e ke+                ++k+ +   p+k+ ++l+++L  +
   EEA21863.1 409 SADlMEEKEDIdelraeisgwkgfddSLKRLRpDLPDKLYTILQRLLAID 458
                  54313334444667999999999999999999889999999999999765 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   9.8e-06     0.025     125     168 ..     304     346 ..     298     357 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 9.8e-06
         Kdo 125 kavgrliaklhragvnHadlyaknillqqeeeeeaeiwliDldk 168
                 k++   i+ lh+ g  H+dl + n ll+  + +e+++ + D+  
  EEA21863.1 304 KDITSGIRFLHANGFIHRDLKPSNCLLHDSG-QELHVLVSDFGE 346
                 788899************************8.999999999965 PP

>> Pox_ser-thr_kin  Poxvirus serine/threonine protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   1.7e-05     0.043     298     325 ..     316     343 ..     310     356 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.7e-05
  Pox_ser-thr_kin 298 enflhvDlkPdniLifdskekliikvke 325
                      + f+h DlkP n L+ ds ++l++ v++
       EEA21863.1 316 NGFIHRDLKPSNCLLHDSGQELHVLVSD 343
                      67********************998876 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.3    0.0003      0.78     163     187 ..     313     337 ..     175     353 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0003
                 SS-EEEE-SS-SGGGEEEC..TTEE CS
         APH 163 elptvllHgDlhpgNllvdpddgrv 187
                   + +++H+Dl+p N l+++ ++++
  EEA21863.1 313 LHANGFIHRDLKPSNCLLHDSGQEL 337
                 56789**************544443 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   4.1e-05       0.1     310     387 ..     301     372 ..     294     401 .. 0.79
   2 ?   -3.1   0.4      0.97   2.5e+03     235     279 ..     512     558 ..     479     588 .. 0.59

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 4.1e-05
  Pkinase_fungal 310 ealrDaIkghrsLflkagiLHrDiSenNilitdskkegerkglLiDLDlakelsddssesgarertGTleFmaievlk 387
                     + ++D   g r L+   g++HrD    N l+ ds   +e + l++D+     ++ ++++      tGT+ + a evl+
      EEA21863.1 301 SFFKDITSGIRFLH-ANGFIHRDLKPSNCLLHDS--GQELHVLVSDFGEVQYENAVRKST---GTTGTISYCAPEVLR 372
                     5688999999****.9****************66..455788999997666666544444...59**********998 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 0.97
  Pkinase_fungal 235 skrkvvsssssqe..lsskaevklkksesskkvekrsvdssvstskr 279
                     ++r+ v+s+++++  ls ++ v+ + ++  ++++++ v++++ ++ r
      EEA21863.1 512 QSRSPVKSVPRSTgsLSVRSPVRYETRSVTSNMKSKAVETDSGSHRR 558
                     33444444444445544444444444444445555555555533322 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (731 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       411  (0.0229238); expected 358.6 (0.02)
Passed bias filter:                      315  (0.0175693); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.61u 0.31s 00:00:00.92 Elapsed: 00:00:00.46
# Mc/sec: 4765.71
//
Query:       EEA21864.1  [L=637]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.7e-35  121.0   2.9    1.4e-34  118.1   3.2    2.3  2  Prefoldin_3      Prefoldin subunit
    3.8e-22   78.9   1.5    3.8e-22   78.9   1.5    4.7  5  DUF3835          Domain of unknown function (DUF3835)
  ------ inclusion threshold ------
          2    8.8   6.7        3.8    7.9   0.1    3.5  4  Val_tRNA-synt_C  Valyl tRNA synthetase tRNA binding arm


Domain annotation for each model (and alignments):
>> Prefoldin_3  Prefoldin subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.1   3.2   2.4e-38   1.4e-34       1      98 [.      26     121 ..      26     122 .. 0.98
   2 ?   -0.9   0.0      0.29   1.7e+03      73      91 ..     420     438 ..     411     443 .. 0.84

  Alignments for each domain:
  == domain 1  score: 118.1 bits;  conditional E-value: 2.4e-38
  Prefoldin_3   1 ekslyklreweaeydglkeeisalkeeddateedllriardfegslvtekEveeilGekqgvtrskqQvvdlisrRiDYVkqniktlekrleaaenkl 98 
                  +ksly++r  eaeydglk+ei++l  ++d+t+ ++l+++ ++eg++v+ekEv++i+Gekq+++rs++Qvv+ i+rR+DYVkqn+++lekrl+aae +l
   EEA21864.1  26 RKSLYDWRLREAEYDGLKDEIKNL--QHDCTSAEILQVGLEYEGTVVDEKEVRDIIGEKQNIMRSRDQVVSQITRRLDYVKQNVASLEKRLSAAEAEL 121
                  589*********************..78*******************************************************************998 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.29
  Prefoldin_3  73 isrRiDYVkqniktlekrl 91 
                  ++r+iD Vk  ++ l+ ++
   EEA21864.1 420 VERKIDAVKSEVAPLSESI 438
                  799******9999887665 PP

>> DUF3835  Domain of unknown function (DUF3835)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0         3   1.8e+04      57      68 ..     144     157 ..     134     160 .. 0.64
   2 ?   -2.1   0.2       1.3   7.5e+03      38      63 ..     269     301 ..     249     310 .. 0.59
   3 ?   -2.7   3.3         2   1.2e+04      24      44 ..     307     328 ..     283     370 .. 0.54
   4 !    7.5   1.9    0.0012       7.4      64      77 ..     457     470 ..     427     471 .. 0.78
   5 !   78.9   1.5   6.3e-26   3.8e-22       2      78 .]     552     635 ..     551     635 .. 0.91

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 3
     DUF3835  57 eiepidedgnp..k 68 
                   e++de+g+    
  EEA21864.1 144 IFEELDENGEVisS 157
                 45778888876444 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.3
     DUF3835  38 lRnkliqr....qggfvks...eeeeeiepide 63 
                 lR+++++      g++v++   +ee +   ide
  EEA21864.1 269 LRREMLEYsfheVGKVVAElemDEEGSDISIDE 301
                 455554443333333333344466666666666 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 2
     DUF3835  24 eellqreva.eeYhrlRnkliq 44 
                 ++ +++e + +eY r+  k++ 
  EEA21864.1 307 DDDDYEEDEdDEYGRTTTKVLT 328
                 3333333221233333333322 PP

  == domain 4  score: 7.5 bits;  conditional E-value: 0.0012
     DUF3835  64 dgnpkkvSRFKAaR 77 
                  g  kk+SRFK+aR
  EEA21864.1 457 TGFTKKTSRFKSAR 470
                 5667*********9 PP

  == domain 5  score: 78.9 bits;  conditional E-value: 6.3e-26
     DUF3835   2 adevvErdi..keaaappdpdeldeellqrevaeeYhrlRnkliqrqggfvks....eeeeeiepidedgnp.kkvSRFKAaRl 78 
                 a+++vEr++  k++  ppdpde+dee++++eva+e++r Rn  iq++ggf+k+    +e  ++ ++de+++p +kvS+FKAaRl
  EEA21864.1 552 AETLVERPVseKTSVLPPDPDEIDEEIHRKEVATEFYRRRNLKIQQSGGFLKDddedDEAAQLYELDENDQPkRKVSKFKAARL 635
                 789******88888888*********************************9998887777788899*9777769*********7 PP

>> Val_tRNA-synt_C  Valyl tRNA synthetase tRNA binding arm
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.1     0.023   1.3e+02       5      22 ..     106     123 ..      91     125 .. 0.74
   2 ?   -3.5   0.0       2.3   1.4e+04      16      37 ..     148     167 ..     146     168 .. 0.69
   3 ?    7.9   0.1   0.00063       3.8      15      54 ..     330     369 ..     324     376 .. 0.87
   4 ?   -3.3   0.2       1.9   1.1e+04      36      44 ..     415     423 ..     414     434 .. 0.60

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.023
  Val_tRNA-synt_C   5 eraRLeKeLaklekeier 22 
                       +a LeK+L+ +e+e++r
       EEA21864.1 106 NVASLEKRLSAAEAELDR 123
                      456678888888888776 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 2.3
  Val_tRNA-synt_C  16 lekeiervqkKLanpgFveKAP 37 
                      l+   e +++K +np   ++AP
       EEA21864.1 148 LDENGEVISSKVSNPA--DRAP 167
                      5566677889999994..5565 PP

  == domain 3  score: 7.9 bits;  conditional E-value: 0.00063
  Val_tRNA-synt_C  15 klekeiervqkKLanpgFveKAPaeVVeeekaklaeleeq 54 
                      ++ +++++++++L   gF++  Pa  Ve+e +  ae+ + 
       EEA21864.1 330 EYHQQMKELEERLKAGGFINLGPAGNVEAEAKETAEATSR 369
                      57789*************************9999988765 PP

  == domain 4  score: -3.3 bits;  conditional E-value: 1.9
  Val_tRNA-synt_C  36 APaeVVeee 44 
                      APa+ Ve++
       EEA21864.1 415 APAAKVERK 423
                      666666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (637 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1379  (0.0769145); expected 358.6 (0.02)
Passed bias filter:                      614  (0.0342462); expected 358.6 (0.02)
Passed Vit filter:                        70  (0.00390429); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.70u 0.30s 00:00:01.00 Elapsed: 00:00:00.49
# Mc/sec: 3940.99
//
Query:       EEA21865.1  [L=378]
Description: CDK-activating kinase assembly factor MAT1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.8e-42  145.5   9.6    2.4e-42  145.1   9.6    1.1  1  MAT1          CDK-activating kinase assembly factor MAT1
      3e-32  110.2   8.9    4.4e-32  109.7   8.9    1.2  1  zf-C3HC4_5    Zinc finger, C3HC4 type (RING finger)
    6.4e-05   22.7   4.1    0.00015   21.5   4.1    1.6  1  zf-C3HC4      Zinc finger, C3HC4 type (RING finger)
     0.0002   21.2   5.7    0.00034   20.4   5.7    1.3  1  zf-C3HC4_3    Zinc finger, C3HC4 type (RING finger)
    0.00023   20.9   4.0    0.00047   20.0   4.0    1.5  1  zf-C3HC4_2    Zinc finger, C3HC4 type (RING finger)
    0.00078   19.7   6.6     0.0013   19.0   6.6    1.4  1  zf-RING_2     Ring finger domain
     0.0058   16.2   1.5      0.011   15.4   1.5    1.4  1  Zn_ribbon_17  Zinc-ribbon, C4HC2 type
  ------ inclusion threshold ------
       0.01   15.6   6.4      0.043   13.6   1.7    2.3  2  zf-RING_4     RING/Ubox like zinc-binding domain
      0.029   14.3   8.5       0.42   10.6   9.0    2.2  2  zf-RING_5     zinc-RING finger domain
      0.099   12.7   6.9       0.19   11.8   6.9    1.5  1  zf-RING_UBOX  RING-type zinc-finger
       0.28   11.1   2.5       0.73    9.8   2.5    1.6  1  DUF3797       Domain of unknown function (DUF3797)
       0.58   10.1   9.6         23    4.9  10.4    2.2  2  Prok-RING_4   Prokaryotic RING finger family 4


Domain annotation for each model (and alignments):
>> MAT1  CDK-activating kinase assembly factor MAT1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.1   9.6   1.6e-45   2.4e-42       1     175 [.      67     242 ..      67     266 .. 0.86

  Alignments for each domain:
  == domain 1  score: 145.1 bits;  conditional E-value: 1.6e-45
        MAT1   1 LRknkFrvQiFeDvevekEvdiRkrvlkifNkkeeDFesLkeYndYLeeveeivfnLtngidveeTekkleqYekenkelIlknkeklkqeeeeleele 99 
                 LRkn+Fr+Q+FeD++ve+EvdiRkrv+ i N++e++F+s  +++++Le+ e+++ nL+ gidv +Te+ l++Ye++n ++I++nk++++qe++ + e++
  EEA21865.1  67 LRKNRFRTQTFEDIGVEREVDIRKRVMAILNRREDEFDSKLDWDNFLEQRETMIMNLVSGIDVAKTEADLRKYEASNLDSIRANKARASQEASSFLEQQ 165
                 9************************************************************************************************** PP

        MAT1 100 elekeekeekrkeekqeeeeekekkekakeelideLatssk.daeeiiekvkkkakkkkssekekleelnkelkkka 175
                  +e+e+ + +r  +++e e+e+++ +  +ee++++La+ +  da +i  + +k   kk+s++++++e+l+++ ++ +
  EEA21865.1 166 SFEQEQARLRRLAAREEYEREQRELAAGREEVLSRLASGRPgDAASIAREGQKILLKKSSARRSEEERLRQKQAALR 242
                 **************************************997466666666665555555555555544444333333 PP

>> zf-C3HC4_5  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  109.7   8.9   2.9e-35   4.4e-32       1      51 []      14      64 ..      14      64 .. 0.99

  Alignments for each domain:
  == domain 1  score: 109.7 bits;  conditional E-value: 2.9e-35
  zf-C3HC4_5  1 deiCPvCkssrYlnpdleflinpeCYhkmCesCvdRlFsdGPnqCPvagCh 51
                de+CP+CkssrYlnpd++flinpeCYhkmCesCvdR+Fs+GPn+CPv+gC+
  EEA21865.1 14 DEVCPICKSSRYLNPDMRFLINPECYHKMCESCVDRIFSSGPNSCPVVGCK 64
                8*************************************************7 PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   4.1     1e-07   0.00015       1      39 [.      17      59 ..      17      60 .. 0.83

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 1e-07
                -TTT-S.--SS-E.....E-TTS--B-CHHHHHHHHCTSSB--T CS
    zf-C3HC4  1 CpiCle.eakepn....elleCkHsfCskCirkilksrkkvkCP 39
                CpiC++  + +p+       eC H++C++C+++i + ++ ++CP
  EEA21865.1 17 CPICKSsRYLNPDmrflINPECYHKMCESCVDRIFS-SGPNSCP 59
                999986245555588877789***************.99999*9 PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   5.7   2.3e-07   0.00034       1      47 [.      13      67 ..      13      69 .. 0.77

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 2.3e-07
                XGSB-TTTSSS.....BS-EEETT.EEEEEE-HHHHHHHHH.TT-B-TT..T--B- CS
  zf-C3HC4_3  1 edeeCviCler.....prnvvllp.CgHlvlCeeCaekllk.rkkkCpi..Crrpi 47
                ede C+iC+++     +  +++ p C H  +Ce+C++++ +   ++Cp+  C++  
  EEA21865.1 13 EDEVCPICKSSrylnpDMRFLINPeCYHK-MCESCVDRIFSsGPNSCPVvgCKKTL 67
                5789******545522333444446****.**********99******98898765 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   4.0   3.1e-07   0.00047       2      39 ..      17      60 ..      16      61 .. 0.84

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 3.1e-07
  zf-C3HC4_2  2 CpiCld.mlkdpsvvt....pCgHvfCqkCilrsLeekn.eCPl 39
                CpiC   ++ +p + +    +C H+ C++C++r  +++  +CP+
  EEA21865.1 17 CPICKSsRYLNPDMRFlinpECYHKMCESCVDRIFSSGPnSCPV 60
                ****86257788555578899*************999999***7 PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.0   6.6   8.7e-07    0.0013       3      42 ..      17      60 ..      15      64 .. 0.77

  Alignments for each domain:
  == domain 1  score: 19.0 bits;  conditional E-value: 8.7e-07
   zf-RING_2  3 CpIC.leelssads..vlll.pCgHvfhreClerwlrssst.CPl 42
                CpIC  +++ ++d   + +  +C H ++++C++r++ s ++ CP+
  EEA21865.1 17 CPICkSSRYLNPDMrfL-INpECYHKMCESCVDRIFSSGPNsCPV 60
                ****6677766555333.4436**************999999**7 PP

>> Zn_ribbon_17  Zinc-ribbon, C4HC2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   1.5   7.1e-06     0.011      15      49 ..      29      63 ..      12      71 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 7.1e-06
  Zn_ribbon_17 15 kgrvvlcgvCeHvlHasCarewfenddlaeCps.GC 49
                    r+++ ++C H + +sC++  f+ +  ++Cp+ GC
    EEA21865.1 29 DMRFLINPECYHKMCESCVDRIFSSGP-NSCPVvGC 63
                  5688999********************.****9999 PP

>> zf-RING_4  RING/Ubox like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.2     0.026        38      34      45 ..      11      22 ..       7      25 .. 0.85
   2 ?   13.6   1.7   2.9e-05     0.043      19      45 ..      37      65 ..      28      68 .. 0.90

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.026
   zf-RING_4 34 eeeegrCPaCre 45
                ++e+++CP C++
  EEA21865.1 11 RDEDEVCPICKS 22
                57899*****97 PP

  == domain 2  score: 13.6 bits;  conditional E-value: 2.9e-05
   zf-RING_4 19 eCgyqiClfCyhrileeeegrCP..aCre 45
                eC +++C  C +ri ++  + CP  +C++
  EEA21865.1 37 ECYHKMCESCVDRIFSSGPNSCPvvGCKK 65
                8**********************777987 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.4     0.039        58      35      43 ..      13      21 ..       5      22 .. 0.81
   2 ?   10.6   9.0   0.00028      0.42       2      44 .]      17      65 ..      16      65 .. 0.81

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.039
   zf-RING_5 35 keavCpiCr 43
                ++ vCpiC+
  EEA21865.1 13 EDEVCPICK 21
                6789****8 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00028
   zf-RING_5  2 CnkCfekl...skeekfyltsCgHifCekClkkll.ekeavCpi..Crk 44
                C++C ++     + +  +  +C+H +Ce+C+++ +   ++ Cp+  C+k
  EEA21865.1 17 CPICKSSRylnPDMRFLINPECYHKMCESCVDRIFsSGPNSCPVvgCKK 65
                999988887844444455568**************999*****988886 PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   6.9   0.00013      0.19       1      39 []      17      59 ..      17      59 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00013
  zf-RING_UBOX  1 CpICl.elftdP....lv.lpCGHtFCreClwelskslegafkCP 39
                  CpIC+ + + +P    l+ ++C H  C++C+   +  ++g  +CP
    EEA21865.1 17 CPICKsSRYLNPdmrfLInPECYHKMCESCV--DRIFSSGPNSCP 59
                  *****6677788866555337**********..677777778887 PP

>> DUF3797  Domain of unknown function (DUF3797)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   2.5   0.00049      0.73      16      43 ..      17      44 ..      14      48 .. 0.93

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00049
     DUF3797 16 CPeCgNnkvlNsegkviieddtfyreCk 43
                CP C+  + lN + +  i+ + + + C+
  EEA21865.1 17 CPICKSSRYLNPDMRFLINPECYHKMCE 44
                ***************************6 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.4     0.063        94      32      38 ..      16      22 ..       9      32 .. 0.78
   2 ?    4.9  10.4     0.015        23       1      41 [.      17      68 ..      17      72 .. 0.72

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.063
  Prok-RING_4 32 sCPlCqr 38
                  CP+C++
   EEA21865.1 16 VCPICKS 22
                 6****86 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.015
  Prok-RING_4  1 CvlCgeq.....ekkailep.CgHlvCkeCfdskdls...sCPl..Cqrris 41
                 C +C+++     +    + p C H +C++C d   +s   sCP+  C++ + 
   EEA21865.1 17 CPICKSSrylnpDMRFLINPeCYHKMCESCVDRIFSSgpnSCPVvgCKKTLR 68
                 566666666655455556666***********99777777***988888764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (378 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1108  (0.0617993); expected 358.6 (0.02)
Passed bias filter:                      499  (0.027832); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2529.15
//
Query:       EEA21866.1  [L=984]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.5e-28   99.0   1.3    1.5e-28   99.0   1.3    3.4  3  Cep57_MT_bd  Centrosome microtubule-binding domain of Cep57
    6.1e-22   77.5   8.0    6.1e-22   77.5   8.0    4.3  4  Cep57_CLD_2  Centrosome localisation domain of PPC89
     0.0034   17.1   1.7     0.0034   17.1   1.7    4.0  4  GrpE         GrpE
  ------ inclusion threshold ------
        4.2    7.2   9.5       0.16   11.8   0.9    2.9  3  DUF3090      Protein of unknown function (DUF3090)


Domain annotation for each model (and alignments):
>> Cep57_MT_bd  Centrosome microtubule-binding domain of Cep57
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   1.1         3   1.3e+04      13      41 ..     345     373 ..     340     387 .. 0.80
   2 ?    2.8   0.1     0.036   1.6e+02      19      42 ..     467     490 ..     465     503 .. 0.84
   3 !   99.0   1.3   3.4e-32   1.5e-28       1      77 []     829     905 ..     829     905 .. 0.99

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 3
  Cep57_MT_bd  13 LaevlkeLedEfehlklelqelaaqynal 41 
                  L   lk L+d ++ l l  +e ++++++ 
   EEA21866.1 345 LFISLKLLQDKVADLELAKAETEKKLEDA 373
                  55568889999999999999999888765 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.036
  Cep57_MT_bd  19 eLedEfehlklelqelaaqynald 42 
                  e + E e lk+e +el+aq n+l+
   EEA21866.1 467 ETKREGEALKKENAELRAQVNKLT 490
                  66789999**************98 PP

  == domain 3  score: 99.0 bits;  conditional E-value: 3.4e-32
  Cep57_MT_bd   1 atlrpsqspkeaLaevlkeLedEfehlklelqelaaqynaldpslgkrkRkdLaeeleelvkrlEaKadqIykLydv 77 
                  +tlrps +p+eaLa+vlk LedE++hlk++l+  ++ + ++d+slgkr+Rk+L +++e+l+k+++ KadqIy+Lydv
   EEA21866.1 829 PTLRPSRPPAEALATVLKSLEDELAHLKMQLAIAQQSFSKHDASLGKRQRKSLSNKIEKLLKEIDTKADQIYALYDV 905
                  699*************************************************************************8 PP

>> Cep57_CLD_2  Centrosome localisation domain of PPC89
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   3.8     0.019        86      35      61 ..     365     395 ..     349     405 .. 0.83
   2 !   77.5   8.0   1.4e-25   6.1e-22       1      67 []     419     485 ..     419     485 .. 0.98
   3 ?   -2.9   0.1       1.7   7.5e+03      10      27 ..     487     505 ..     487     513 .. 0.77
   4 ?    0.8   1.7      0.12   5.5e+02       6      41 ..     846     893 ..     841     922 .. 0.56

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.019
  Cep57_CLD_2  35 salrqLgvAyeelneLkaevealrkE....L 61 
                  + +++L +A+ee+  Lk e  +++kE    L
   EEA21866.1 365 ETEKKLEDAREENHLLKVEKSRRQKEqydrL 395
                  5689*********************954443 PP

  == domain 2  score: 77.5 bits;  conditional E-value: 1.4e-25
  Cep57_CLD_2   1 LeaevktLqnrLdsltrklqvheeelkrLnkERdsalrqLgvAyeelneLkaevealrkELkeqrae 67 
                  Lea +++LqnrLd+++rk+qvhe++lk+L++ERdsa++qLgvAy++++e k+e eal+kE+ e ra+
   EEA21866.1 419 LEAMNLALQNRLDIADRKVQVHESALKSLAQERDSAVTQLGVAYLNTQETKREGEALKKENAELRAQ 485
                  89***********************************************************999976 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 1.7
  Cep57_CLD_2  10 nrLdsltrklqvhe.eelk 27 
                  n+L+ ltr+l  +e ++++
   EEA21866.1 487 NKLTVLTRELLGNEtDTRQ 505
                  8999999999988855555 PP

  == domain 4  score: 0.8 bits;  conditional E-value: 0.12
  Cep57_CLD_2   6 ktLqnrLdsltrklqvhe............eelkrLnkERdsalrqLg 41 
                  k+L+++L +l  +l++++              +k+L++  +  l+ + 
   EEA21866.1 846 KSLEDELAHLKMQLAIAQqsfskhdaslgkRQRKSLSNKIEKLLKEID 893
                  566666666666666666544433365555555555554444444444 PP

>> GrpE  GrpE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -6.0   7.6         4   1.8e+04      29      43 ..     364     378 ..     339     459 .. 0.53
   2 ?   -2.1   4.3       0.6   2.7e+03      11      59 ..     469     531 ..     462     538 .. 0.50
   3 ?   -3.1   0.3       1.2   5.6e+03      73      73 ..     638     638 ..     595     666 .. 0.48
   4 !   17.1   1.7   7.6e-07    0.0034      12     115 ..     836     934 ..     826     939 .. 0.89

  Alignments for each domain:
  == domain 1  score: -6.0 bits;  conditional E-value: 4
                 TSCCCCCCTTTTTTT CS
        GrpE  29 kelkekllrllaefe 43 
                 +e ++kl+ +++e +
  EEA21866.1 364 AETEKKLEDAREENH 378
                 222222222222222 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.6
                 HHHHCCCCCCTTCHHHCTTSCCCCCC..............TTTTTTTTHHHHHHHHHHHHHHH CS
        GrpE  11 edeeeeleeeleelekevkelkekll..............rllaefenlrkrtekekeeakkf 59 
                 + e e+l++e +el+++v++l+                  + + e en++  t+++  + +k+
  EEA21866.1 469 KREGEALKKENAELRAQVNKLTVLTRellgnetdtrqslpKNQLETENVTASTDQNEGNTQKT 531
                 334444444444444444433211111113333333333377778888887777777666665 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 1.2
                 H CS
        GrpE  73 D 73 
                 D
  EEA21866.1 638 D 638
                 2 PP

  == domain 4  score: 17.1 bits;  conditional E-value: 7.6e-07
                 HHHCCCCCCTTCHHHCTTSCCCCCCTTTTTTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC..HHH-HHHHHHHHHHHHHHHHHHHHHTT CS
        GrpE  12 deeeeleeeleelekevkelkekllrllaefenlrkrtekekeeakkfaiekfakdLLpvlDnleralksakeneeekslleGvemtlkqllkiLekhg 110
                 +  e+l + l++le+e+++lk +l  +++ f ++   + k++ +  + +iek++k++   +D++    + +     e +  +G emt+k+++ +L++ g
  EEA21866.1 836 PPAEALATVLKSLEDELAHLKMQLAIAQQSFSKHDASLGKRQRKSLSNKIEKLLKEIDTKADQIYALYDVV-----EGQKQDGHEMTEKEMEVTLQSIG 929
                 5677888899******************************************************9999974.....445568***************** PP

                 -EE-- CS
        GrpE 111 vekie 115
                 + +++
  EEA21866.1 930 IDVQS 934
                 98765 PP

>> DUF3090  Protein of unknown function (DUF3090)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.3         1   4.6e+03      69      79 ..     473     483 ..     413     538 .. 0.56
   2 ?   -0.6   0.1      0.22     1e+03     129     159 ..     648     679 ..     598     686 .. 0.73
   3 ?   11.8   0.9   3.6e-05      0.16      36     124 ..     872     961 ..     859     972 .. 0.76

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 1
     DUF3090  69 eeelkdeepLe 79 
                 e+ +k++++L+
  EEA21866.1 473 EALKKENAELR 483
                 22333333333 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.22
     DUF3090 129 alrv.rltreqarafakrarevvaaGrpsCpl 159
                 +l++ r+tr+q r++a+r +  v+++  +C  
  EEA21866.1 648 RLEMeRATRKQNRSLAAREQPAVTSAPAKCVA 679
                 444326899999******99999999999976 PP

  == domain 3  score: 11.8 bits;  conditional E-value: 3.6e-05
     DUF3090  36 alekeqvaaLaerieelLdelarreg..asvPaeaeeelkdeepLeepveeeFrvgtlalawDeetervviealaleeeeedeel..deeeee 124
                  l k q + L+++ie+lL+e++++++   ++ ++ e +++d +++   +e+e +v   +++ D ++++++ +++ ++++   +++  ++e+++
  EEA21866.1 872 SLGKRQRKSLSNKIEKLLKEIDTKADqiYALYDVVEGQKQDGHEM---TEKEMEVTLQSIGIDVQSAAMLANLTGATDQSLRQKAarNAEDSD 961
                 5789******************99874444444445555555555...8999*********************99999888555544222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (984 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1559  (0.0869541); expected 358.6 (0.02)
Passed bias filter:                      495  (0.0276089); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.81u 0.30s 00:00:01.11 Elapsed: 00:00:00.46
# Mc/sec: 6368.74
//
Query:       EEA21867.1  [L=413]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0016   17.8   3.6     0.0027   17.1   3.6    1.4  1  SKG6      Transmembrane alpha-helix domain


Domain annotation for each model (and alignments):
>> SKG6  Transmembrane alpha-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   3.6   1.5e-07    0.0027       8      36 ..      21      49 ..      16      51 .. 0.89

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 1.5e-07
        SKG6  8 ntvaIavaVaVPVaViiivLlailifvrR 36
                 t+a +v+Va+ V++ +++L++i+++vrR
  EEA21867.1 21 GTTAAGVGVAIAVGASVLALIFIFVMVRR 49
                57788999999999**************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (413 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1186  (0.0661498); expected 358.6 (0.02)
Passed bias filter:                      543  (0.0302861); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.47
# Mc/sec: 2641.88
//
Query:       EEA21868.1  [L=1351]
Description: ABC a-pheromone efflux pump AtrD [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.5e-67  226.6  37.6      1e-33  117.1  17.9    2.3  2  ABC_membrane    ABC transporter transmembrane region
    7.3e-58  194.9   0.0    4.8e-29  101.6   0.0    2.8  2  ABC_tran        ABC transporter
    9.8e-17   61.1   4.3    4.4e-07   29.6   0.1    4.9  4  SMC_N           RecF/RecN/SMC N terminal domain
    2.7e-09   37.3   0.3       0.55   10.0   0.0    4.3  4  AAA_21          AAA domain, putative AbiEii toxin, Type IV TA
    7.5e-09   35.2   0.5     0.0025   17.5   0.0    2.6  2  AAA_29          P-loop containing region of AAA domain
    1.5e-08   34.7   0.2    0.00043   20.2   0.0    2.5  2  RsgA_GTPase     RsgA GTPase
    5.1e-07   30.2   0.7     0.0081   16.6   0.0    3.4  2  AAA_16          AAA ATPase domain
    1.4e-06   28.6   0.8        0.2   11.9   0.1    4.5  4  AAA_22          AAA domain
    1.7e-06   28.1   0.1     0.0052   16.9   0.0    2.6  2  MMR_HSR1        50S ribosome-binding GTPase
    9.8e-06   26.2   0.6       0.11   13.0   0.2    2.4  2  AAA_23          AAA domain
    1.7e-05   24.6   0.1      0.057   13.1   0.0    3.6  2  AAA_30          AAA domain
    7.4e-05   23.0   0.3       0.29   11.2   0.1    2.6  2  DUF87           Helicase HerA, central domain
    9.1e-05   21.8   0.0      0.015   14.6   0.0    2.3  2  Zeta_toxin      Zeta toxin
    0.00048   19.8   0.2        2.1    7.8   0.0    3.5  4  AAA_25          AAA domain
    0.00083   19.2   1.2       0.37   10.4   0.0    2.5  2  AAA_15          AAA ATPase domain
     0.0023   18.0   0.1       0.95    9.5   0.0    2.4  2  Dynamin_N       Dynamin family
     0.0025   17.2   0.0        1.6    8.0   0.0    2.4  2  FtsK_SpoIIIE    FtsK/SpoIIIE family
     0.0039   17.4   0.8          1    9.6   0.0    3.2  2  SbcCD_C         Putative exonuclease SbcCD, C subunit
     0.0047   15.8   6.1        2.1    7.0   0.1    3.9  4  ABC_ATPase      Predicted ATPase of the ABC class
     0.0075   16.0   0.0        5.4    6.8   0.0    3.0  3  DEAD            DEAD/DEAH box helicase
  ------ inclusion threshold ------
      0.011   15.5   1.2        1.1    8.9   0.0    3.5  4  IstB_IS21       IstB-like ATP binding protein
      0.011   15.0   0.4        0.3   10.3   0.0    2.5  2  Septin          Septin
      0.018   14.7   0.3        1.7    8.2   0.0    2.5  2  cobW            CobW/HypB/UreG, nucleotide-binding domain
      0.038   14.1   0.9        8.8    6.5   0.1    2.6  2  AAA_33          AAA domain
      0.044   13.7   0.0        9.4    6.1   0.0    3.0  2  NACHT           NACHT domain
       0.06   12.9   0.1        7.7    6.0   0.0    2.4  2  AAA_7           P-loop containing dynein motor region
      0.062   12.6   2.1        6.6    6.0   0.0    3.2  3  ATPase          KaiC
        0.1   12.5   0.2        4.6    7.1   0.0    2.4  2  Ploopntkinase3  P-loop Nucleotide Kinase3
       0.12   12.8   0.2        7.9    6.9   0.0    2.6  2  RNA_helicase    RNA helicase
       0.13   12.9   0.3         25    5.4   0.1    2.6  2  AAA_18          AAA domain
       0.13   12.2   0.4         29    4.6   0.1    3.4  3  AAA_5           AAA domain (dynein-related subfamily)
       0.14   11.8   0.2         23    4.6   0.0    2.5  2  AAA_24          AAA domain
       0.15   10.9   1.9        6.8    5.5   0.1    2.7  3  AAA_10          AAA-like domain
       0.16   11.6   0.1        1.3    8.7   0.0    2.3  2  Guanylate_kin   Guanylate kinase
       0.19   10.7   0.1        6.8    5.6   0.0    2.2  2  DUF3987         Protein of unknown function (DUF3987)
       0.43   10.5   3.6        7.7    6.4   0.1    3.6  3  NTPase_1        NTPase


Domain annotation for each model (and alignments):
>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.1  17.9   2.1e-36     1e-33       2     271 ..      52     327 ..      51     331 .. 0.95
   2 !  115.1  11.7     9e-36   4.5e-33       2     270 ..     775    1044 ..     774    1048 .. 0.95

  Alignments for each domain:
  == domain 1  score: 117.1 bits;  conditional E-value: 2.1e-36
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSS...TCCHH......HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTH CS
  ABC_membrane   2 iliillailagvlsplfplvlgrildtlldk...gdpet......ealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpm 89 
                   +++i+ +i agv  ++f+l+lg++++tl+++   +           +      +ll+lg + ++l+ + +++++v +e ++++  + lf k+l  ++
    EEA21868.1  52 LAAIIITISAGVSRIIFALYLGKLFQTLSQFgigA---ItgpqlmDKARDNTSILLILGGGTWLLNSFFFFVWIVFAEFQVREAGSILFGKLLTRDL 145
                   7899**************************95552...4455677667888999999**************************************** PP

                   HHHHH..SCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane  90 sffdt..nsvGellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvae 184
                    +fd     vG +ls+  ++++ l+ ++++ lg f+  ++ +++g+i++f+++w +tlv++a +p+ + v+ + ++++ ++ k +q+++++as++++
    EEA21868.1 146 VWFDMrkDGVGPFLSHSQKQLRELQIATAQPLGAFILHIIRILAGMILAFVISWEVTLVTMAGIPVSFTVITFTSSRMAPILKAQQSELSEASKITY 242
                   *****6556**************************************************************************************** PP

                   HHHHTHHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSTHHHHHHHHHHHHHHH CS
  ABC_membrane 185 EslsgirtVkafgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttlvisgelsvgdlvvflslfailf 271
                   ++++ i +Vk++++++  +++    ++ a + ++k a++ +++ ++ +++++++++  +w+G+ lv+sg+l++gd  v+++++  l+
    EEA21868.1 243 DAFKSIDVVKCLNGQSSTYTQMMTRINAAARLYMKLAVLISIQTAFPRFMSFVMFVQGFWYGSILVQSGKLTPGD--VLTTFWGCLI 327
                   ***************************************************************************..9999987554 PP

  == domain 2  score: 115.1 bits;  conditional E-value: 9e-36
                    HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSTCCHH.HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHHHH. CS
  ABC_membrane    2 iliillailagvlsplfplvlgrildtlldkgdpet.ealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsffdt. 94  
                     ++i+la ++    p+f+++l+r++d++     ++  +  + ys+ +++l +a+++++++ +y+l ++++ ++ +lr++ ++++l qp s+f++ 
    EEA21868.1  775 AIAIVLATIHATSTPIFSFLLSRLFDSFYIADRTKAsSIAKTYSISIVSLSVADALVTFVMNYILEYCSQAWMDKLRARSMQRVLAQPCSWFEQk 869 
                    799***********************9988644444678999****************************************************9 PP

                    .SCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane   95 .nsvGellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEsls 188 
                     +++ +l+  l   ++  r++ g + + ++ s++t ++++++++ l w+lt+v l ++p+ + vs+ +  + ++ ++  ++ ++++ +v+ E+++
    EEA21868.1  870 dHDPLQLTICLDQHAEETRNLAGKFGSFVIISIITAFIAIVWSLNLKWQLTFVSLLCAPVWYGVSKGLQAVNTRWERSLNDLNEDMANVFSEAFT 964 
                    999******************************************************************************************** PP

                    THHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSTHHHHHHHHHHHHHH CS
  ABC_membrane  189 girtVkafgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttlvisgelsvgdlvvflslfail 270 
                     + tV+af+ e+ f+ k  + l++ +  g+k+ i++gl++g t++++ ++ al ++++++l   ++  +++  ++++l ++l
    EEA21868.1  965 DVATVRAFTLENHFRAKLANVLRRRLMVGFKRGIYTGLFFGLTESVIIFASALLIYYAAVLTAPDAKGISN--IVSVLTMTL 1044
                    *************************************************************9998888888..444444444 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.6   0.0   9.6e-32   4.8e-29       1     136 [.     399     550 ..     399     551 .. 0.88
   2 !   90.3   0.0     3e-28   1.5e-25       1     137 []    1115    1276 ..    1115    1276 .. 0.88

  Alignments for each domain:
  == domain 1  score: 101.6 bits;  conditional E-value: 9.6e-32
                 EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH..........HHHTCHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..........xxxxxxxxxx RF
    ABC_tran   1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren..........esdeeiekal 89 
                 l+ +++k+ +g+++ ivG++GaGKStL++ll++ ++p++G il+ g++++     ++rk++  ++q++ lf+e+ + +n           s++++e  +
  EEA21868.1 399 LNALNIKFPAGRTTFIVGRSGAGKSTLINLLLQFYSPKSGGILVGGTPFQAVHPAWVRKNVTLVQQNNYLFNET-LWDNiafgarrprsVSNDQMEMCI 496
                 67899********************************************************************9.99999*******995555544444 PP

                 HHSTTGG.......TTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 xxxxxxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  90 sklglke.......lkdtvvksspssLSgGqkqrvalarallkkpkllllDEpt 136
                 +  +l++         +tvv+ +++ LSgGqkqrva+ara +k++ +l+lDE t
  EEA21868.1 497 EMANLQDaihnlpnELNTVVGLGGNLLSGGQKQRVAIARARMKNSAVLILDEFT 550
                 444444444444445699**9999****************************77 PP

  == domain 2  score: 90.3 bits;  conditional E-value: 3e-28
                  EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--...SEEEE.....EETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.......... CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......... RF
    ABC_tran    1 lknvslklkegekvaivGenGaGKStLlkllagllkp...teGei.....lldgkdlkeqeleslrkeigvlpqepqlfpeltvren.......... 79  
                  l n slk+ e+++ aivG++G+GKSt+++ll+gl+       G+      +l g d+++  ++ lr+ ig++pq+p+lf ++ +r n          
  EEA21868.1 1115 LTNFSLKIPENSCSAIVGSSGSGKSTIISLLLGLYACpnpSPGQDivaplTLAGVDIRQLHIPTLRSMIGYVPQQPKLFADT-IRANityglgpysr 1210
                  6899*******************************875555555456888999*****************************.9***********99 PP

                  ..........HHHTCHHHHHHHSTTGGTTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                  ..........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran   80 ..........esdeeiekalsklglkelkdtvvksspssLSgGqkqrvalarallkkpkllllDEpta 137 
                            +  + i++++++l       t +++++ +LSgGq qr+++aral+++p++l+lDE+t+
  EEA21868.1 1211 fnslnnieaaAGAAGIADFIHSLPEGF--STLIGEGGLTLSGGQAQRLVIARALVRHPRILILDEATS 1276
                  977666544333333788888887777..99999999*****************************96 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.6   0.1   8.8e-10   4.4e-07      25     200 ..     410     582 ..     400     595 .. 0.72
   2 ?   -0.1   0.0         1   5.2e+02     141     163 ..     770     792 ..     701     794 .. 0.92
   3 !    7.7   0.2    0.0043       2.2      23      42 ..    1124    1143 ..    1117    1150 .. 0.85
   4 !   19.0   0.0   1.5e-06   0.00075     136     212 ..    1247    1323 ..    1160    1329 .. 0.84

  Alignments for each domain:
  == domain 1  score: 29.6 bits;  conditional E-value: 8.8e-10
                 SEEEEEESTTSSHHHHHHHHHHHCTT.TTTTTTCHCCCCCC--BTTCSSTTEEEEEEEEEETTEE....SSSSSSCEEEEEEEETTSE.EEEEETTEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxx.xxxxxxxxxx RF
       SMC_N  25 sftaivGpNGSGKsnlldAilFvLGersakklrseklsdlihkskekasvkkaeveitfdnedkk....lkiekeevsisrrvkrkge.seykingkev 118
                 + t+ivG+ G+GKs l++ +l   + +s   l   +  + +h      +  + +v+++ +n+       +  ++  +  +r  + +++  e+ i+  + 
  EEA21868.1 410 RTTFIVGRSGAGKSTLINLLLQFYSPKSGGILVGGTPFQAVHP-----AWVRKNVTLVQQNN--YlfneTLWDNIAFGARRPRSVSNDqMEMCIEMANL 501
                 5799************999966666666655555555555554.....44444455542222..21221334555566666555444437888877777 PP

                 -H..HHHHHHHHC.TT-STTCS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHH CS
                 xx..xxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 119 tk..kevselles.agiskelLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQfivislree 200
                 +   +++ + l++ +g+  +lLSgG+k+ va+a      ++k +++ +lDe+  aLD  n++ v e +++ +  +  i++++++ 
  EEA21868.1 502 QDaiHNLPNELNTvVGLGGNLLSGGQKQRVAIA----RARMKNSAVLILDEFTGALDYDNRATVMESVRKWRYGMTTIIVTHDTA 582
                 6655677777765369************99875....679*****************************************9876 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 1
                 HHHHHHHHHHHHHHCCS--SEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 141 ektLvalaLlfAiqkvkpaplyl 163
                 ++ L+a+a+++A+ ++  +p++ 
  EEA21868.1 770 QRILLAIAIVLATIHATSTPIFS 792
                 7889***********99999986 PP

  == domain 3  score: 7.7 bits;  conditional E-value: 0.0043
                  TSSEEEEEESTTSSHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxx RF
       SMC_N   23 sksftaivGpNGSGKsnlld 42  
                  ++s +aivG+ GSGKs ++ 
  EEA21868.1 1124 ENSCSAIVGSSGSGKSTIIS 1143
                  56789************985 PP

  == domain 4  score: 19.0 bits;  conditional E-value: 1.5e-06
                  CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHH....HHCTTSEEEEE-SSHHHCCC-SCEEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  136 lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellk....eksknaQfivislreemlekadklvgvt 212 
                  +LSgG+    a  L++A   v+   + +lDe  ++LD +  +++ + ++    +  ++  +i+++++++m+e ad++v v 
  EEA21868.1 1247 TLSGGQ----AQRLVIARALVRHPRILILDEATSNLDTESAEIIRRSVRrlltAPGQELTVIMVTHSKDMMEMADNVVVVD 1323
                  588888....558889988999999**************988776655521116678899****************99875 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.4   0.1    0.0017      0.82       2      22 ..     412     432 ..     411     463 .. 0.76
   2 ?    6.3   0.0     0.015       7.4     250     299 ..     532     582 ..     521     586 .. 0.82
   3 !   10.0   0.0    0.0011      0.55       3      24 ..    1129    1150 ..    1127    1180 .. 0.81
   4 ?    6.3   0.1     0.015       7.4     247     299 ..    1257    1310 ..    1231    1314 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0017
      AAA_21   2 nvliGpNgsGKSnLLdaldll 22 
                 ++++G+ g+GKS+L+ +l  +
  EEA21868.1 412 TFIVGRSGAGKSTLINLLLQF 432
                 89***************9544 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.015
      AAA_21 250 allralkkg.sllliDEpEngLHPkllrrllellkelsrngaQviltTHS.p 299
                 a++ra+ k+ ++l++DE+   L++   ++++e ++ + r g   i++TH+  
  EEA21868.1 532 AIARARMKNsAVLILDEFTGALDYDNRATVMESVR-KWRYGMTTIIVTHDtA 582
                 6777777777************************4.4455999******955 PP

  == domain 3  score: 10.0 bits;  conditional E-value: 0.0011
      AAA_21    3 vliGpNgsGKSnLLdaldllar 24  
                  +++G  gsGKS+++ +l +l  
  EEA21868.1 1129 AIVGSSGSGKSTIISLLLGLYA 1150
                  89***************99965 PP

  == domain 4  score: 6.3 bits;  conditional E-value: 0.015
      AAA_21  247 lltallralkkgsllliDEpEngLHPkllrrllell.kelsr..ngaQviltTHSp 299 
                  +++  l +++  ++l++DE  ++L+ +  + + + + ++l++      vi++THS 
  EEA21868.1 1257 VIARALVRHP--RILILDEATSNLDTESAEIIRRSVrRLLTApgQELTVIMVTHSK 1310
                  4555555565..9*************66655555553223334457*********5 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   0.0   5.1e-06    0.0025      17      39 ..     404     426 ..     399     437 .. 0.82
   2 !   15.3   0.1   2.6e-05     0.013      18      39 ..    1121    1142 ..    1115    1152 .. 0.81

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 5.1e-06
      AAA_29  17 ieidlkg.atlltGpsGsGKSTll 39 
                 i++  +g +t+++G+sG+GKSTl+
  EEA21868.1 404 IKFP-AGrTTFIVGRSGAGKSTLI 426
                 5565.5669**************9 PP

  == domain 2  score: 15.3 bits;  conditional E-value: 2.6e-05
      AAA_29   18 eidlkgatlltGpsGsGKSTll 39  
                  +i +++   ++G sGsGKST++
  EEA21868.1 1121 KIPENSCSAIVGSSGSGKSTII 1142
                  566566899************9 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.0   8.6e-07   0.00043      98     121 ..     408     431 ..     377     440 .. 0.85
   2 !   11.8   0.1   0.00034      0.17      99     121 ..    1125    1147 ..    1115    1152 .. 0.87

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 8.6e-07
                  TTSEEEEECSTTSSHHHHHHHHCT CS
  RsgA_GTPase  98 kdktsvlvGqSGvGKStLinallp 121
                  +++t+++vG SG+GKStLin ll+
   EEA21868.1 408 AGRTTFIVGRSGAGKSTLINLLLQ 431
                  459*****************9976 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 0.00034
                   TSEEEEECSTTSSHHHHHHHHCT CS
  RsgA_GTPase   99 dktsvlvGqSGvGKStLinallp 121 
                   +++s++vG+SG GKSt+i  ll+
   EEA21868.1 1125 NSCSAIVGSSGSGKSTIISLLLG 1147
                   6899**************99875 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   1.6e-05    0.0081      24      63 ..     409     449 ..     397     558 .. 0.78
   2 !    8.8   0.7    0.0038       1.9      25      52 ..    1126    1159 ..    1115    1304 .. 0.42

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 1.6e-05
      AAA_16  24 pelvllsGesGvGKsslvrellralekd.ggiflrgkcdql 63 
                 ++ ++++G sG GKs+l++ ll+ ++ + ggi++ g+  q 
  EEA21868.1 409 GRTTFIVGRSGAGKSTLINLLLQFYSPKsGGILVGGTPFQA 449
                 3789******************9888884577777776665 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0038
      AAA_16   25 elvllsGesGvGKsslvrellr.alekd.....g 52  
                  ++  ++G sG+GKs+++  ll  +++ +     +
  EEA21868.1 1126 SCSAIVGSSGSGKSTIISLLLGlYACPNpspgqD 1159
                  67789************99995333333444441 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.9   0.1    0.0004       0.2       8      30 ..     412     434 ..     408     577 .. 0.82
   2 ?   -2.0   0.0         8     4e+03      21      56 ..     854     890 ..     852     898 .. 0.81
   3 !    8.0   0.0    0.0065       3.2       6      26 ..    1126    1146 ..    1123    1167 .. 0.89
   4 ?    2.9   0.0      0.25   1.3e+02      86     112 ..    1257    1289 ..    1210    1310 .. 0.65

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.0004
      AAA_22   8 lvvtGesGtGKTtllrrlleqld 30 
                 ++++G sG+GK+tl++ ll+ + 
  EEA21868.1 412 TFIVGRSGAGKSTLINLLLQFYS 434
                 78****************99874 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 8
      AAA_22  21 llrrlleqldeeakaeeerpevvfvtlpsst.sskdl 56 
                 +++r+l q + + ++++++p +++++l +   + ++l
  EEA21868.1 854 SMQRVLAQPCSWFEQKDHDPLQLTICLDQHAeETRNL 890
                 899*****************99999988777555555 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.0065
      AAA_22    6 gilvvtGesGtGKTtllrrll 26  
                  ++ +++G sG+GK+t +  ll
  EEA21868.1 1126 SCSAIVGSSGSGKSTIISLLL 1146
                  7889***********998876 PP

  == domain 4  score: 2.9 bits;  conditional E-value: 0.25
      AAA_22   86 lrarav...ielliiDEaqh.lr..seealeeL 112 
                  + ara    +++li+DEa   l+  s+e+++  
  EEA21868.1 1257 VIARALvrhPRILILDEATSnLDteSAEIIRRS 1289
                  33333344556*******999955444444443 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.0     1e-05    0.0052       3      38 ..     413     454 ..     411     505 .. 0.80
   2 !    8.5   0.0     0.004         2       3      21 ..    1129    1147 ..    1127    1164 .. 0.87

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 1e-05
                 EEEESTTSSHHHHHHHHHT.....S.TEEESSSTTSSSSEEE CS
    MMR_HSR1   3 aivGrpNvGKStLinaltg.....e.kaivsdkpgtTrdine 38 
                  ivGr+ +GKStLin l++     +    v+ +p+   ++ +
  EEA21868.1 413 FIVGRSGAGKSTLINLLLQfyspkSgGILVGGTPFQAVHPAW 454
                 69***************9754432234567777776666655 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.004
                  EEEESTTSSHHHHHHHHHT CS
    MMR_HSR1    3 aivGrpNvGKStLinaltg 21  
                  aivG + +GKSt+i+ l+g
  EEA21868.1 1129 AIVGSSGSGKSTIISLLLG 1147
                  8**************9987 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.0   0.2   0.00022      0.11      14      39 ..     403     429 ..     399     432 .. 0.82
   2 !   10.8   0.0     0.001      0.52      18      38 ..    1124    1144 ..    1101    1167 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 0.00022
      AAA_23  14 eidF.skgltlItGpNGaGKTTildAi 39 
                 +i F     t I+G  GaGK+T+++ +
  EEA21868.1 403 NIKFpAGRTTFIVGRSGAGKSTLINLL 429
                 6777545789**************976 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.001
      AAA_23   18 skgltlItGpNGaGKTTildA 38  
                  ++   +I+G  G+GK+Ti+  
  EEA21868.1 1124 ENSCSAIVGSSGSGKSTIISL 1144
                  666789************964 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.1   0.0   0.00011     0.057      19     118 ..     410     573 ..     405     582 .. 0.64
   2 ?    6.3   0.0     0.014       6.8      19      43 ..    1126    1150 ..    1121    1306 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 0.00011
      AAA_30  19 rvavltGpAGtGKttalkalreaweaa.ggrviglAptgkaAkv.La.................................e..elgieastiakllkrl 80 
                 r+++++G+ G+GK+t+++ l + +  + gg ++g +p +++  + ++                                 +  e+ ie ++++  +++l
  EEA21868.1 410 RTTFIVGRSGAGKSTLINLLLQFYSPKsGGILVGGTPFQAVHPAwVRknvtlvqqnnylfnetlwdniafgarrprsvsnDqmEMCIEMANLQDAIHNL 508
                 5789********************999886666666666555443443333333444443333333333333333222221223334555555555555 PP

      AAA_30  81 k........................grarlepgtllivDEa.gmvdtkqlaallkaaek..agak 118
                                          +rar++++ +li DE  g +d ++ a+++++++k  +g++
  EEA21868.1 509 PnelntvvglggnllsggqkqrvaiARARMKNSAVLILDEFtGALDYDNRATVMESVRKwrYGMT 573
                 58888888999999999999999887788888899999995266688888888888887433554 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.014
      AAA_30   19 rvavltGpAGtGKttalkalreawe 43  
                   +++++G  G+GK+t+++ l  +++
  EEA21868.1 1126 SCSAIVGSSGSGKSTIISLLLGLYA 1150
                  5789************998876665 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.0   0.0    0.0026       1.3      27      57 ..     413     442 ..     392     442 .. 0.83
   2 !   11.2   0.1   0.00059      0.29      26      44 ..    1128    1146 ..    1124    1155 .. 0.92

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.0026
       DUF87  27 AilgsTGsGKSntvavLleellekkgatili 57 
                  i+g++G+GKS+++ +Ll+     k++ il+
  EEA21868.1 413 FIVGRSGAGKSTLINLLLQFYS-PKSGGILV 442
                 599***************9777.66777765 PP

  == domain 2  score: 11.2 bits;  conditional E-value: 0.00059
       DUF87   26 lAilgsTGsGKSntvavLl 44  
                  +Ai+gs+GsGKS+ +++Ll
  EEA21868.1 1128 SAIVGSSGSGKSTIISLLL 1146
                  69**************998 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   2.9e-05     0.015      19      83 ..     412     469 ..     405     478 .. 0.82
   2 ?    4.5   0.0     0.037        19      21      36 ..    1130    1145 ..    1125    1154 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 2.9e-05
  Zeta_toxin  19 illgGqpGAGKselaellkdelerqgnvvrldpDdlRelhPeyeeilkadpkkaseltqkdasel 83 
                  +++G +GAGKs+l++ll +   ++++ + + ++ +++ hP           k++ l+q+  + +
  EEA21868.1 412 TFIVGRSGAGKSTLINLLLQFYSPKSGGILVGGTPFQAVHPAWVR-------KNVTLVQQNNYLF 469
                 689**************************************9776.......4555555544444 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.037
  Zeta_toxin   21 lgGqpGAGKselaell 36  
                  ++G++G+GKs++++ll
  EEA21868.1 1130 IVGSSGSGKSTIISLL 1145
                  78***********987 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.8   0.0    0.0043       2.1      22      50 ..     399     426 ..     380     451 .. 0.81
   2 ?   -1.6   0.0       3.3   1.6e+03     138     188 ..     537     579 ..     522     580 .. 0.72
   3 ?   -2.8   0.0       7.8   3.9e+03      83     122 ..     941     977 ..     906     989 .. 0.66
   4 !    7.1   0.0    0.0073       3.6      30      53 ..    1122    1145 ..    1098    1165 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0043
      AAA_25  22 rrwlvkgllpagelallaGapgtGKttla 50 
                 ++ l   + pag ++ ++G++g+GK+tl 
  EEA21868.1 399 LNALNIKF-PAGRTTFIVGRSGAGKSTLI 426
                 55555555.9*****************96 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 3.3
      AAA_25 138 eevegvrlvviDplsralggdensnsdvgalvealeriarrtgaavllvhH 188
                 +  ++ +++++D ++ al+ d+      + ++e ++++  r+g ++++v H
  EEA21868.1 537 RM-KNSAVLILDEFTGALDYDNR-----ATVMESVRKW--RYGMTTIIVTH 579
                 33.66889999999998888776.....5667777777..67777777777 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 7.8
      AAA_25  83 edelrrRlravgealrddarllvldlagveslpLfakdrg 122
                 + +++r l  + e+++    ++++d+a+v   + f+++++
  EEA21868.1 941 NTRWERSLNDLNEDMANVFSEAFTDVATV---RAFTLENH 977
                 34678888888888888999999998886...44444444 PP

  == domain 4  score: 7.1 bits;  conditional E-value: 0.0073
      AAA_25   30 lpagelallaGapgtGKttlaldl 53  
                  +p+++ ++++G +g+GK+t+ + l
  EEA21868.1 1122 IPENSCSAIVGSSGSGKSTIISLL 1145
                  89*****************98766 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.4   0.0   0.00075      0.37      25      55 ..     411     457 ..     399     513 .. 0.74
   2 ?    6.6   0.6     0.011       5.5      18      43 ..    1119    1145 ..    1115    1149 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00075
      AAA_15  25 ltvliGkNnsGKSsilealdlFlnnkekkn...................k 55 
                 +t+++G+ ++GKS+++++l  F + k   +                   k
  EEA21868.1 411 TTFIVGRSGAGKSTLINLLLQFYSPK---SggilvggtpfqavhpawvrK 457
                 8*******************999988...333355555555665544442 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.011
      AAA_15   18 eidlsee.ltvliGkNnsGKSsileal 43  
                  ++++ e+  + ++G  +sGKS+i+ +l
  EEA21868.1 1119 SLKIPENsCSAIVGSSGSGKSTIISLL 1145
                  5555555599**************988 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.5   0.0    0.0019      0.95       3      29 ..     414     440 ..     413     514 .. 0.83
   2 ?    5.9   0.1     0.025        12       2      22 ..    1129    1149 ..    1129    1159 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.0019
                 EEEBTTTTHHHHHHHHHTS--S---SS CS
   Dynamin_N   3 vvGsqSsGKSSvlnaLlgedilprgpn 29 
                 +vG   +GKS+++n Ll+     +g +
  EEA21868.1 414 IVGRSGAGKSTLINLLLQFYSPKSGGI 440
                 79***************9874444444 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.025
                  EEEEBTTTTHHHHHHHHHTS- CS
   Dynamin_N    2 avvGsqSsGKSSvlnaLlged 22  
                  a+vGs  sGKS+++  Llg  
  EEA21868.1 1129 AIVGSSGSGKSTIISLLLGLY 1149
                  69***************9965 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   0.0    0.0032       1.6       8      60 ..     363     430 ..     358     433 .. 0.78
   2 !    6.5   0.0    0.0096       4.8      43      61 ..    1129    1146 ..    1113    1156 .. 0.80

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0032
                   SHHHHT---TTEEEEEEETTS-EEEEEGGGS-................SEEEE--TTSSHHHHHHHHH CS
  FtsK_SpoIIIE   8 skkfrtessqlpvalgkeisgnplvldlkkma...............shllvaGatgsGKStalntLi 60 
                   +  frt++ + p++  ++i+ +++v+ +++ +                 + ++G++g GKSt +n L+
    EEA21868.1 363 DLRFRTQKNRYPNLHTEDIVLKNVVFAYPSRPeipvlnalnikfpagRTTFIVGRSGAGKSTLINLLL 430
                   556777777777777788877777777777777778888888888877899*************9987 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0096
                    EEE--TTSSHHHHHHHHHH CS
  FtsK_SpoIIIE   43 lvaGatgsGKStalntLil 61  
                     ++G++gsGKSt +  L l
    EEA21868.1 1129 AIVGSSGSGKSTIISLL-L 1146
                    79**********98644.3 PP

>> SbcCD_C  Putative exonuclease SbcCD, C subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.1     0.079        39      60      89 ..     537     566 ..     522     567 .. 0.83
   2 !    9.6   0.0    0.0021         1      62      82 ..    1264    1284 ..    1244    1291 .. 0.82

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.079
     SbcCD_C  60 repalrlvfLDEAFsklDeesiatllelle 89 
                 r ++ ++++LDE  + lD +++at++e ++
  EEA21868.1 537 RMKNSAVLILDEFTGALDYDNRATVMESVR 566
                 45667899******************9876 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.0021
     SbcCD_C   62 palrlvfLDEAFsklDeesia 82  
                  +++r+++LDEA s+lD es++
  EEA21868.1 1264 RHPRILILDEATSNLDTESAE 1284
                  569**************9986 PP

>> ABC_ATPase  Predicted ATPase of the ABC class
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.1      0.14        71     243     263 ..     407     428 ..     401     432 .. 0.85
   2 !    7.0   0.1    0.0043       2.1     295     376 ..     494     575 ..     486     589 .. 0.85
   3 ?   -2.3   0.1         3   1.5e+03     246     262 ..    1127    1143 ..    1120    1149 .. 0.77
   4 !    6.9   0.1    0.0045       2.3     301     412 ..    1225    1323 ..    1219    1330 .. 0.73

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.14
                 -SS.EEEEEE-TTSSHHHHHHH CS
  ABC_ATPase 243 pkG.vtlIvGggfhGKsTLLeA 263
                 p G  t IvG+   GKsTL++ 
  EEA21868.1 407 PAGrTTFIVGRSGAGKSTLINL 428
                 5666799************985 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0043
                 --EEEE--TTTB---CCC--ST.TEEESS--HHHHHHHHHHHHHHTT-SEEEEEGGGS-HHHH---HHHHHHS-GGG--B--H CS
  ABC_ATPase 295 rsvkgvDispFinnLPegkdtt.kfstedASGStsqAanimealeagakllLiDEDtsAtNlmirDermqelvskekepitpl 376
                 ++++ ++++  i+nLP++ +t      +  SG   q ++i++a   ++ +l++DE t A     r + m+++  k++ ++t++
  EEA21868.1 494 MCIEMANLQDAIHNLPNELNTVvGLGGNLLSGGQKQRVAIARARMKNSAVLILDEFTGALDYDNRATVMESVR-KWRYGMTTI 575
                 6789999**************956666678***************************9988877777777654.666666665 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 3
                  EEEEEE-TTSSHHHHHH CS
  ABC_ATPase  246 vtlIvGggfhGKsTLLe 262 
                    +IvG+   GKsT+++
  EEA21868.1 1127 CSAIVGSSGSGKSTIIS 1143
                  678***********985 PP

  == domain 4  score: 6.9 bits;  conditional E-value: 0.0045
                  --TTTB---CCC--ST.TEEESS--HHHHHHHHHHHHHHTT-SEEEEEGGGS-HHHH---HHHHHHS-GGG--B--HHHCHHHHHHHH--E.EEEEE CS
  ABC_ATPase  301 DispFinnLPegkdtt.kfstedASGStsqAanimealeagakllLiDEDtsAtNlmirDermqelvskekepitplvdrvrelykklgvs.tilvv 395 
                   i  Fi++LPeg +t       + SG   q   i++al +  ++l++DE ts  Nl   D+  +e++   ++        vr+l +  g   t++ v
  EEA21868.1 1225 GIADFIHSLPEGFSTLiGEGGLTLSGGQAQRLVIARALVRHPRILILDEATS--NL---DTESAEII---RR-------SVRRLLTAPGQElTVIMV 1306
                  5889**********9966666788*************************887..44...55666666...22.......233333333333044444 PP

                  SS-GCCTTT-SEEEEEE CS
  ABC_ATPase  396 ggsgdyldvAdtvilme 412 
                    s+d++++Ad+v++++
  EEA21868.1 1307 THSKDMMEMADNVVVVD 1323
                  67788888888888765 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.0     0.027        13      77     146 ..     491     565 ..     400     577 .. 0.68
   2 ?   -2.3   0.0       6.4   3.2e+03      19      34 ..    1130    1145 ..    1122    1163 .. 0.85
   3 ?    6.8   0.0     0.011       5.4     119     164 ..    1263    1305 ..    1209    1310 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.027
                 EEEEEETTSSHHHHHHHHHTTCSEEEEEHHHHHHHHHCTSSH.....CTTEEEEEEETHHHHHHTTTHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  77 rvlliiggvaardqlskldngvdivvgtpgrlddllstgkln.....lsqvrflVlDEadrlldqgfsdfinril 146
                 +++++i+  + +d + +l n+++ vvg  g l++  +++++      +++  +l+lDE  + ld + + ++ + +
  EEA21868.1 491 QMEMCIEMANLQDAIHNLPNELNTVVGLGGNLLSGGQKQRVAiararMKNSAVLILDEFTGALDYDNRATVMESV 565
                 445568888899999999999************97755554444556999999******9999987666665555 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 6.4
                  EEESTTSSHHHHHHHH CS
                  xxxxxxxxxxxxxxxx RF
        DEAD   19 vaaeTGsGKTlaflip 34  
                  + +  GsGK+++ ++ 
  EEA21868.1 1130 IVGSSGSGKSTIISLL 1145
                  56789*****998875 PP

  == domain 3  score: 6.8 bits;  conditional E-value: 0.011
                  CTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTST.TTSEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxx RF
        DEAD  119 lsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgk.lqrqviv 164 
                  +++ r+l+lDEa   ld +  + i+r +++l   t+ g+ l+  vi+
  EEA21868.1 1263 VRHPRILILDEATSNLDTESAEIIRRSVRRL--LTAPGQeLT--VIM 1305
                  7889**************************9..455544333..555 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0       2.2   1.1e+03      50      63 ..     412     425 ..     406     429 .. 0.85
   2 ?    8.9   0.0    0.0022       1.1      89     148 ..     521     580 ..     510     600 .. 0.77
   3 ?    2.4   0.0      0.23   1.1e+02      46      72 ..    1124    1151 ..    1114    1155 .. 0.78
   4 ?   -2.5   0.0       7.3   3.6e+03     106     128 ..    1263    1284 ..    1251    1295 .. 0.69

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 2.2
   IstB_IS21  50 ivllGpsGvGKshl 63 
                   ++G sG+GKs l
  EEA21868.1 412 TFIVGRSGAGKSTL 425
                 5799*******987 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.0022
   IstB_IS21  89 elkrarrdgklaralkrllkvdllilDdlgllpldqaeaellfevi.ekryerrsiiitsn 148
                 +l    +++++a a +r+ ++++lilD++    ld +++++++e + + ry+ ++ii+t +
  EEA21868.1 521 NLLSGGQKQRVAIARARMKNSAVLILDEFTG-ALDYDNRATVMESVrKWRYGMTTIIVTHD 580
                 555666778888899999**********964.45666666666655166*********965 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.23
   IstB_IS21   46 kkenivllGpsGvGKshl.aialgveav 72  
                  ++ + +++G sG GKs + +  lg  a+
  EEA21868.1 1124 ENSCSAIVGSSGSGKSTIiSLLLGLYAC 1151
                  678999*********8651556666666 PP

  == domain 4  score: -2.5 bits;  conditional E-value: 7.3
   IstB_IS21  106 llkvdllilDdlgllpldqaeae 128 
                  + ++++lilD+  + +ld ++ae
  EEA21868.1 1263 VRHPRILILDEA-TSNLDTESAE 1284
                  345699****96.4566666665 PP

>> Septin  Septin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   0.00059       0.3       6      73 ..     411     480 ..     408     497 .. 0.68
   2 ?    1.9   0.0      0.23   1.1e+02       9      25 ..    1130    1146 ..    1128    1154 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00059
                 EEEEEEBTTSSCCCCCCTTSSSS------------..------S-EEEEEEEEETTCEEEEEEEE---BS CS
      Septin   6 tlmvvGesglGkttlintlfetdlieeekleease..kkkktveikkkkvvieedgvklnltviDtpgfG 73 
                 t ++vG+sg Gk+tlin l++    ++  +       ++ +   ++k+ +++++++  +n t+ D   fG
  EEA21868.1 411 TTFIVGRSGAGKSTLINLLLQFYSPKSGGILVGGTpfQAVHPAWVRKNVTLVQQNNYLFNETLWDNIAFG 480
                 5689**************9987666664433322223445555566666666666666666666665555 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.23
                  EEEBTTSSCCCCCCTTS CS
      Septin    9 vvGesglGkttlintlf 25  
                  +vG+sg Gk+t+i  l+
  EEA21868.1 1130 IVGSSGSGKSTIISLLL 1146
                  89**********98775 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   0.0    0.0034       1.7       2      33 ..     411     442 ..     410     463 .. 0.84
   2 ?    4.0   0.0     0.067        33       3      21 ..    1128    1146 ..    1126    1156 .. 0.84

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0034
                 EEEEEESTTCCHHHHHHHHHCT--SS-EEEEE CS
        cobW   2 vtvltGflGsGKTtLlnhllenraglklaviv 33 
                 +t ++G  G+GK+tL+n ll+  + ++  ++v
  EEA21868.1 411 TTFIVGRSGAGKSTLINLLLQFYSPKSGGILV 442
                 5789**************99876666666655 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.067
                  EEEEESTTCCHHHHHHHHH CS
        cobW    3 tvltGflGsGKTtLlnhll 21  
                  + ++G+ GsGK+t+++ ll
  EEA21868.1 1128 SAIVGSSGSGKSTIISLLL 1146
                  5799**********98776 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.1     0.018       8.8       3      21 ..     413     431 ..     412     442 .. 0.89
   2 ?    5.3   0.1      0.04        20       4      19 ..    1130    1145 ..    1129    1150 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.018
      AAA_33   3 llvGlpGsGKstlaerllk 21 
                 ++vG +G+GKstl+  ll+
  EEA21868.1 413 FIVGRSGAGKSTLINLLLQ 431
                 789**********988775 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.04
      AAA_33    4 lvGlpGsGKstlaerl 19  
                  +vG +GsGKst +  l
  EEA21868.1 1130 IVGSSGSGKSTIISLL 1145
                  69*********98765 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.0     0.019       9.4       1      20 [.     410     429 ..     410     434 .. 0.88
   2 ?    4.0   0.0     0.084        42       3      28 ..    1128    1153 ..    1126    1187 .. 0.81

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.019
                 SCEEEEC-TTTCHHHHHHHH CS
       NACHT   1 rlvilqGeaGsGKTtLlqkl 20 
                 r+ ++ G++G GK+tL+  l
  EEA21868.1 410 RTTFIVGRSGAGKSTLINLL 429
                 7899************8765 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.084
                  EEEEC-TTTCHHHHHHHHHHHHCTS- CS
       NACHT    3 vilqGeaGsGKTtLlqklalawaegk 28  
                  +++ G +GsGK+t +  l  + a ++
  EEA21868.1 1128 SAIVGSSGSGKSTIISLLLGLYACPN 1153
                  689**********9887776666655 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.0     0.016       7.7      32      58 ..     408     434 ..     400     441 .. 0.84
   2 ?    4.2   0.0     0.056        28      32      53 ..    1124    1145 ..    1114    1150 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.016
       AAA_7  32 nkkpvllvGptGtGKtviikdllkkld 58 
                 +++ +++vG +G GK+++i+ ll+ ++
  EEA21868.1 408 AGRTTFIVGRSGAGKSTLINLLLQFYS 434
                 678899*************99887665 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.056
       AAA_7   32 nkkpvllvGptGtGKtviikdl 53  
                  ++    +vG++G+GK++ii+ l
  EEA21868.1 1124 ENSCSAIVGSSGSGKSTIISLL 1145
                  5566679***********9865 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.0     0.013       6.6      15      35 ..     405     425 ..     395     433 .. 0.86
   2 ?    3.5   0.0     0.079        39      16      35 ..    1122    1141 ..    1116    1145 .. 0.89
   3 ?    0.3   0.2      0.75   3.7e+02     122     166 ..    1268    1311 ..    1259    1328 .. 0.78

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.013
      ATPase  15 GipegrvvlitGepGtGKtif 35 
                  +p gr++ i+G +G+GK+++
  EEA21868.1 405 KFPAGRTTFIVGRSGAGKSTL 425
                 59*****************97 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.079
      ATPase   16 ipegrvvlitGepGtGKtif 35  
                  ipe++   i+G++G+GK+++
  EEA21868.1 1122 IPENSCSAIVGSSGSGKSTI 1141
                  89***************975 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.75
      ATPase  122 rvviDsitglayeekeavaReilrqlvrvlkklgvTailvsekss 166 
                   +++D  t+   +e+++ +R+ +r+l++   + ++T i+v+  ++
  EEA21868.1 1268 ILILDEATSNLDTESAEIIRRSVRRLLTA-PGQELTVIMVTHSKD 1311
                  567888887769999999********987.677889999987544 PP

>> Ploopntkinase3  P-loop Nucleotide Kinase3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.0    0.0092       4.6       4      27 ..     410     433 ..     408     438 .. 0.86
   2 ?    2.6   0.0      0.22   1.1e+02       8      26 ..    1130    1148 ..    1127    1167 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0092
  Ploopntkinase3   4 rliylvGqPGaGkstlmaeltkgf 27 
                     r  ++vG  GaGkstl+  l + +
      EEA21868.1 410 RTTFIVGRSGAGKSTLINLLLQFY 433
                     778*************99887766 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.22
  Ploopntkinase3    8 lvGqPGaGkstlmaeltkg 26  
                      +vG+ G+Gkst+++ l   
      EEA21868.1 1130 IVGSSGSGKSTIISLLLGL 1148
                      89**********9987655 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.0     0.016       7.9       2      20 ..     413     431 ..     412     465 .. 0.76
   2 ?    3.0   0.1      0.27   1.3e+02       3      18 ..    1130    1145 ..    1129    1152 .. 0.88

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.016
  RNA_helicase   2 wlyGpsgeGKStlakeLak 20 
                   +++G+sg GKStl++ L +
    EEA21868.1 413 FIVGRSGAGKSTLINLLLQ 431
                   689************9654 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.27
  RNA_helicase    3 lyGpsgeGKStlakeL 18  
                    ++G+sg GKSt++  L
    EEA21868.1 1130 IVGSSGSGKSTIISLL 1145
                    78*********99875 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   0.1     0.051        25       2      19 ..     413     434 ..     413     553 .. 0.66
   2 ?    4.7   0.0     0.083        42       3      18 ..    1130    1145 ..    1129    1176 .. 0.83

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.051
      AAA_18   2 lltGtpGvGKttlakeL....s 19 
                 ++ G +G+GK+tl + L    s
  EEA21868.1 413 FIVGRSGAGKSTLINLLlqfyS 434
                 58999**********9955553 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.083
      AAA_18    3 ltGtpGvGKttlakeL 18  
                  + G +G+GK+t+   L
  EEA21868.1 1130 IVGSSGSGKSTIISLL 1145
                  899*********9988 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.1     0.059        29       3      23 ..     413     433 ..     411     443 .. 0.87
   2 ?   -1.4   0.0       4.3   2.1e+03      59      75 ..     534     550 ..     521     554 .. 0.76
   3 ?    3.3   0.0      0.15        75       4      23 ..    1130    1149 ..    1128    1156 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.059
                 EEE--SSSSHHHHHHHGGGGB CS
       AAA_5   3 lLvGppGtgKselaerlaaal 23 
                 ++vG +G gKs+l+  l++++
  EEA21868.1 413 FIVGRSGAGKSTLINLLLQFY 433
                 89*************999876 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 4.3
                 ------G-SEEEEESGG CS
       AAA_5  59 lvraaregeilvlDEve 75 
                 +   ++++++l+lDE++
  EEA21868.1 534 ARARMKNSAVLILDEFT 550
                 445688*********98 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.15
                  EE--SSSSHHHHHHHGGGGB CS
       AAA_5    4 LvGppGtgKselaerlaaal 23  
                  +vG +G+gKs+++  l+ ++
  EEA21868.1 1130 IVGSSGSGKSTIISLLLGLY 1149
                  79***********9998877 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.0     0.046        23       4      22 ..     411     429 ..     408     437 .. 0.84
   2 ?    4.5   0.0     0.052        26       6      22 ..    1129    1145 ..    1125    1156 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.046
      AAA_24   4 kiliyGpsgiGKTtlakel 22 
                   +i+G sg+GK+tl++ l
  EEA21868.1 411 TTFIVGRSGAGKSTLINLL 429
                 6789***********9866 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.052
      AAA_24    6 liyGpsgiGKTtlakel 22  
                  +i+G+sg+GK+t+++ l
  EEA21868.1 1129 AIVGSSGSGKSTIISLL 1145
                  79**********99876 PP

>> AAA_10  AAA-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.1     0.014       6.8      23      46 ..     411     434 ..     399     442 .. 0.83
   2 ?   -3.1   0.1       5.6   2.8e+03     238     289 ..     538     587 ..     531     590 .. 0.74
   3 ?    3.9   0.0     0.041        20      20      41 ..    1124    1145 ..    1112    1151 .. 0.76

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.014
      AAA_10  23 asliiGdlGnGKSvlakllvlyis 46 
                  ++i+G  G+GKS l++ll  + s
  EEA21868.1 411 TTFIVGRSGAGKSTLINLLLQFYS 434
                 469***************998876 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 5.6
      AAA_10 238 kkefkvvifDEawiftssaeGkkllkelvRiGRsynaavylvtqsadDvlke 289
                  k  +v i+DE     + ++ ++++ e+vR+ R  ++  ++vt+++  +l++
  EEA21868.1 538 MKNSAVLILDEFTGALDYDNRATVM-ESVRKWRYGMT-TIIVTHDTANILDD 587
                 5677899999999999998877765.56788886665.56789999988765 PP

  == domain 3  score: 3.9 bits;  conditional E-value: 0.041
      AAA_10   20 nasasliiGdlGnGKSvlakll 41  
                  ++s s+i+G+ G GKS ++ ll
  EEA21868.1 1124 ENSCSAIVGSSGSGKSTIISLL 1145
                  46668***********998876 PP

>> Guanylate_kin  Guanylate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.0    0.0026       1.3       3      34 ..     410     442 ..     408     448 .. 0.86
   2 ?   -0.2   0.0       1.4   7.1e+02       7      23 ..    1130    1146 ..    1127    1151 .. 0.89

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0026
                    SEEEEESTTTSSHHHHHHHHHHHSTTTEE.E-- CS
  Guanylate_kin   3 rpvvlvgpsgaGksslkkaLlselpekfg.vsv 34 
                    r+  +vg sgaGks+l++ Ll+ ++ k g + v
     EEA21868.1 410 RTTFIVGRSGAGKSTLINLLLQFYSPKSGgILV 442
                    8889*******************9998864776 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 1.4
                     EESTTTSSHHHHHHHHH CS
  Guanylate_kin    7 lvgpsgaGksslkkaLl 23  
                     +vg sg Gks++++ Ll
     EEA21868.1 1130 IVGSSGSGKSTIISLLL 1146
                     89***********9998 PP

>> DUF3987  Protein of unknown function (DUF3987)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0     0.014       6.8      39      59 ..     412     432 ..     403     435 .. 0.88
   2 ?    2.6   0.1      0.11        57      39      58 ..    1128    1147 ..    1119    1150 .. 0.85

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.014
     DUF3987  39 tlvvapsGerKSpvdklvlrp 59 
                 t++v++sG +KS++ +l+l+ 
  EEA21868.1 412 TFIVGRSGAGKSTLINLLLQF 432
                 89**************99875 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.11
     DUF3987   39 tlvvapsGerKSpvdklvlr 58  
                   ++v++sG++KS++ +l+l 
  EEA21868.1 1128 SAIVGSSGSGKSTIISLLLG 1147
                  589***********998875 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.1     0.015       7.7       3      32 ..     413     444 ..     411     463 .. 0.77
   2 ?    1.9   0.0      0.38   1.9e+02       4      19 ..    1130    1145 ..    1128    1150 .. 0.85
   3 ?   -0.2   0.2       1.6     8e+02      91     146 ..    1260    1321 ..    1250    1332 .. 0.63

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.015
                 EEE--TTSSHHHHHHHHHHHH.....GGGEEE CS
    NTPase_1   3 fiTGppGvGKtTlvkkvlell..kssgvkvgG 32 
                 fi G++G GK+Tl++ +l+    ks g+ vgG
  EEA21868.1 413 FIVGRSGAGKSTLINLLLQFYspKSGGILVGG 444
                 899************99886511333555555 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.38
                  EE--TTSSHHHHHHHH CS
    NTPase_1    4 iTGppGvGKtTlvkkv 19  
                  i G++G+GK+T+++ +
  EEA21868.1 1130 IVGSSGSGKSTIISLL 1145
                  789*********9876 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 1.6
                  HHH.HHH-EEEE---.STTGGG-HHH.HHHHHHHHT...TTSEEEEE--SS--SHHHHHHHT CS
    NTPase_1   91 kal.seadviviDEi.GkmElkskkf.keaveevLk...sekpvlavihrrkdlalveeire 146 
                  +al +++ ++++DE   ++  +s+++ +++v+++L+   +e  v++v h ++  ++ +++  
  EEA21868.1 1260 RALvRHPRILILDEAtSNLDTESAEIiRRSVRRLLTapgQELTVIMVTHSKDMMEMADNVVV 1321
                  444478889999996256898888752679*****963223345666666655555555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1351 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       913  (0.0509231); expected 358.6 (0.02)
Passed bias filter:                      577  (0.0321825); expected 358.6 (0.02)
Passed Vit filter:                        97  (0.00541023); expected 17.9 (0.001)
Passed Fwd filter:                        36  (0.00200792); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              36  [number of targets reported over threshold]
# CPU time: 1.06u 0.35s 00:00:01.41 Elapsed: 00:00:00.49
# Mc/sec: 8209.51
//
Query:       EEA21869.1  [L=149]
Description: DUF757 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.9e-23   81.7   1.0    1.4e-21   76.9   1.0    2.0  1  Polysacc_synt_4  Polysaccharide biosynthesis


Domain annotation for each model (and alignments):
>> Polysacc_synt_4  Polysaccharide biosynthesis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.9   1.0   7.9e-26   1.4e-21       2     187 ..      17     139 ..      16     142 .. 0.97

  Alignments for each domain:
  == domain 1  score: 76.9 bits;  conditional E-value: 7.9e-26
  Polysacc_synt_4   2 EislavkvlerrevpcnlLvFGlghesllwkslnkggrlvlleeddeivekvkkefpeleayevkYktkvsdadeLlsaakkeaecrpvqnlla 95 
                      E+++avk++e+  +++++L           +++ +g++l+l+++ddei+e++k+efp+++      +++++++d+++s+a+k            
       EEA21869.1  17 EKQFAVKAVEQLMTYWSIL-----------EKV-PGSKLRLTKMDDEILEHFKREFPDFD------PAATINEDDMKSKAGK------------ 80 
                      99*****************...........***.*************************8......9***************............ PP

  Polysacc_synt_4  96 sdckLalrdLPnevyeekWDvilvDaprgfaeeapgrmediytagvlaRarkseeyseetdvfvhdvqrkvekafseeFlceeiavnregl..l 187
                                      ekW        r+f++e+++ ++d y++g+++R++ ++ey++e ++f++++q          F+++eia+nr+gl  +
       EEA21869.1  81 ----------------EKW--------RNFMKEYEKTISD-YNFGTMLRSNPKAEYDQESTIFAMRMQ----------FYAIEIARNRAGLndW 139
                      ................***........*************.***************************..........************8655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (149 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       793  (0.04423); expected 358.6 (0.02)
Passed bias filter:                      459  (0.025601); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.24s 00:00:00.64 Elapsed: 00:00:00.39
# Mc/sec: 1140.60
//
Query:       EEA21870.1  [L=121]
Description: DUF757 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.6e-20   72.8   0.8    9.2e-19   67.7   0.8    2.0  1  Polysacc_synt_4  Polysaccharide biosynthesis


Domain annotation for each model (and alignments):
>> Polysacc_synt_4  Polysaccharide biosynthesis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.7   0.8   5.1e-23   9.2e-19      31     187 ..       7     111 ..       2     114 .. 0.95

  Alignments for each domain:
  == domain 1  score: 67.7 bits;  conditional E-value: 5.1e-23
  Polysacc_synt_4  31 wkslnkggrlvlleeddeivekvkkefpeleayevkYktkvsdadeLlsaakkeaecrpvqnllasdckLalrdLPnevyeekWDvilvDaprg 124
                      ++++ +g++l+l+++ddei+e++k+efp+++      +++++++d+++s+a+k                            ekW        r+
       EEA21870.1   7 LEKV-PGSKLRLTKMDDEILEHFKREFPDFD------PAATINEDDMKSKAGK----------------------------EKW--------RN 57 
                      5788.99***********************8......9***************............................***........** PP

  Polysacc_synt_4 125 faeeapgrmediytagvlaRarkseeyseetdvfvhdvqrkvekafseeFlceeiavnregl..l 187
                      f++e+++ ++d y++g+++R++ ++ey++e ++f++++q          F+++eia+nr+gl  +
       EEA21870.1  58 FMKEYEKTISD-YNFGTMLRSNPKAEYDQESTIFAMRMQ----------FYAIEIARNRAGLndW 111
                      ***********.***************************..........************8655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (121 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       766  (0.0427241); expected 358.6 (0.02)
Passed bias filter:                      459  (0.025601); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 838.59
//
Query:       EEA21871.1  [L=121]
Description: DUF757 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.6e-20   72.8   0.8    9.2e-19   67.7   0.8    2.0  1  Polysacc_synt_4  Polysaccharide biosynthesis


Domain annotation for each model (and alignments):
>> Polysacc_synt_4  Polysaccharide biosynthesis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.7   0.8   5.1e-23   9.2e-19      31     187 ..       7     111 ..       2     114 .. 0.95

  Alignments for each domain:
  == domain 1  score: 67.7 bits;  conditional E-value: 5.1e-23
  Polysacc_synt_4  31 wkslnkggrlvlleeddeivekvkkefpeleayevkYktkvsdadeLlsaakkeaecrpvqnllasdckLalrdLPnevyeekWDvilvDaprg 124
                      ++++ +g++l+l+++ddei+e++k+efp+++      +++++++d+++s+a+k                            ekW        r+
       EEA21871.1   7 LEKV-PGSKLRLTKMDDEILEHFKREFPDFD------PAATINEDDMKSKAGK----------------------------EKW--------RN 57 
                      5788.99***********************8......9***************............................***........** PP

  Polysacc_synt_4 125 faeeapgrmediytagvlaRarkseeyseetdvfvhdvqrkvekafseeFlceeiavnregl..l 187
                      f++e+++ ++d y++g+++R++ ++ey++e ++f++++q          F+++eia+nr+gl  +
       EEA21871.1  58 FMKEYEKTISD-YNFGTMLRSNPKAEYDQESTIFAMRMQ----------FYAIEIARNRAGLndW 111
                      ***********.***************************..........************8655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (121 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       766  (0.0427241); expected 358.6 (0.02)
Passed bias filter:                      459  (0.025601); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.47
# Mc/sec: 778.57
//
Query:       EEA21872.1  [L=474]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.2e-110  369.8   0.1   5.8e-110  368.5   0.0    1.6  2  Ric8      Guanine nucleotide exchange factor synembryn


Domain annotation for each model (and alignments):
>> Ric8  Guanine nucleotide exchange factor synembryn
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1      0.05     9e+02     423     438 ..      16      31 ..      13      44 .. 0.75
   2 !  368.5   0.0  3.3e-114  5.8e-110       3     459 .]      48     461 ..      46     461 .. 0.93

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.05
        Ric8 423 eEKErEAerLfvlfdr 438
                  EK  E+ rL++ +dr
  EEA21872.1  16 TEKQSEVRRLVDSLDR 31 
                 5888888888888888 PP

  == domain 2  score: 368.5 bits;  conditional E-value: 3.3e-114
        Ric8   3 etLkilgRdpkgldplftkeaistLlklafdssstsaslekeseeevareAlrcLaNalllsekarqrlverlkggeekavellkkdksspadieflds 101
                  tL+ +g +p+++d +++k++++ L+k+  d + ++ +          r Alr++aNalll++++rq lv+  +g   +++e+lk+d   ++++e++ +
  EEA21872.1  48 LTLRQHGTNPDNADAIYSKNGVALLIKYGLDGEIPDIR----------RGALRTIANALLLKSDMRQVLVD--TGCVGRLAEKLKTD---NSEDEMIVA 131
                 79*************************97777777777..........***********************..9***********99...********* PP

        Ric8 102 RllFLlTaleseirkelkelveeesllaealeqilkrkakevsssdeaasslskeesealselLKllFnltlhypksvldeeeaeelseklarllppll 200
                 R+lFL+T++ ++++  +k+l+ e+s l e++++++ r++k++   ++ ++ l+++++ a +++LKllFn++   p          +l++++++++p +l
  EEA21872.1 132 RILFLTTYD-TDLN--FKTLITEHS-LGENIHYQIIRHSKQIP--KSGKKTLTPIDEAAFTDVLKLLFNVCKLNP----------DLADTFTQSIPYML 214
                 *********.9988..*********.**************777..999***************************..........56677********* PP

        Ric8 201 rlllllpipspdpLkpplthlinaLlnlpleeskkeaalfpss...aegnnmdvvsrllelldkrlaaadekkdkdaeleekltpllllLtklaeaa.e 295
                 ++++++++p++ pL+ ++++l+naL++l+l+++  +   f+ss    + n++++v++l+++ld ++++++      ++le++++pl+ lL +++e+a e
  EEA21872.1 215 KIITRIDVPQQ-PLDGLISYLVNALSTLDLSDKPGK---FESSpffPKFNPNCNVDKLINVLDAAVRHYE----A-DQLETRIVPLIELLLTIYEQApE 304
                 ***********.9*****************999886...4433345677*****************7766....3.368******************9* PP

        Ric8 296 evRkylrerlLPplrDrskrlekgdtlrgrllRlmtsvstprlkdavaelLFvLckedasrlvkyvGYGnaAGfLankgllsaqpeyssdsedsdteey 394
                   Rky+++ lLP+++Drs++++++dtl+++ll l+t++s  +lk+a++el+F L+ ++a++l+k++GYG+aAGfLa++g+ +  p+ ++   +  ++++
  EEA21872.1 305 GPRKYMEWLLLPEDQDRSVPIGRSDTLSSKLLVLSTTPSV-HLKTAISELFFFLSGKNAETLTKNIGYGYAAGFLASRGIEI--PQDAN---EAFATNQ 397
                 **************************************99.*****************************************..55433...4467888 PP

        Ric8 395 kqakraiNPiTGqveeeee..enpleeMTeeEKErEAerLfvlfdrlektgviqvenPvekagedGr 459
                 ++ + a NPiTGq +++e+  ++p   MTeeEKErEAerLfvlf+r + +g i  enPv++a+++Gr
  EEA21872.1 398 SNINPAFNPITGQRWDAEPqdTGP--AMTEEEKEREAERLFVLFERARANGFIA-ENPVAQAVREGR 461
                 899****************77777..***************************7.6**********8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (474 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       457  (0.0254894); expected 358.6 (0.02)
Passed bias filter:                      414  (0.0230911); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 3072.64
//
Query:       EEA21873.1  [L=458]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.7e-104  349.8   0.1   7.9e-104  348.2   0.0    1.6  2  Ric8      Guanine nucleotide exchange factor synembryn


Domain annotation for each model (and alignments):
>> Ric8  Guanine nucleotide exchange factor synembryn
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.1     0.048   8.7e+02     423     438 ..      16      31 ..      13      44 .. 0.75
   2 !  348.2   0.0  4.4e-108  7.9e-104       3     438 ..      48     441 ..      46     444 .. 0.93

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.048
        Ric8 423 eEKErEAerLfvlfdr 438
                  EK  E+ rL++ +dr
  EEA21873.1  16 TEKQSEVRRLVDSLDR 31 
                 5888888888888888 PP

  == domain 2  score: 348.2 bits;  conditional E-value: 4.4e-108
        Ric8   3 etLkilgRdpkgldplftkeaistLlklafdssstsaslekeseeevareAlrcLaNalllsekarqrlverlkggeekavellkkdksspadieflds 101
                  tL+ +g +p+++d +++k++++ L+k+  d + ++ +          r Alr++aNalll++++rq lv+  +g   +++e+lk+d   ++++e++ +
  EEA21873.1  48 LTLRQHGTNPDNADAIYSKNGVALLIKYGLDGEIPDIR----------RGALRTIANALLLKSDMRQVLVD--TGCVGRLAEKLKTD---NSEDEMIVA 131
                 79*************************97777777777..........***********************..9***********99...********* PP

        Ric8 102 RllFLlTaleseirkelkelveeesllaealeqilkrkakevsssdeaasslskeesealselLKllFnltlhypksvldeeeaeelseklarllppll 200
                 R+lFL+T++ ++++  +k+l+ e+s l e++++++ r++k++   ++ ++ l+++++ a +++LKllFn++   p          +l++++++++p +l
  EEA21873.1 132 RILFLTTYD-TDLN--FKTLITEHS-LGENIHYQIIRHSKQIP--KSGKKTLTPIDEAAFTDVLKLLFNVCKLNP----------DLADTFTQSIPYML 214
                 *********.9988..*********.**************777..999***************************..........56677********* PP

        Ric8 201 rlllllpipspdpLkpplthlinaLlnlpleeskkeaalfpss...aegnnmdvvsrllelldkrlaaadekkdkdaeleekltpllllLtklaeaa.e 295
                 ++++++++p++ pL+ ++++l+naL++l+l+++  +   f+ss    + n++++v++l+++ld ++++++      ++le++++pl+ lL +++e+a e
  EEA21873.1 215 KIITRIDVPQQ-PLDGLISYLVNALSTLDLSDKPGK---FESSpffPKFNPNCNVDKLINVLDAAVRHYE----A-DQLETRIVPLIELLLTIYEQApE 304
                 ***********.9*****************999886...4433345677*****************7766....3.368******************9* PP

        Ric8 296 evRkylrerlLPplrDrskrlekgdtlrgrllRlmtsvstprlkdavaelLFvLckedasrlvkyvGYGnaAGfLankgllsaqpeyssdsedsdteey 394
                   Rky+++ lLP+++Drs++++++dtl+++ll l+t++s  +lk+a++el+F L+ ++a++l+k++GYG+aAGfLa++g+ +  p+ ++   +  ++++
  EEA21873.1 305 GPRKYMEWLLLPEDQDRSVPIGRSDTLSSKLLVLSTTPSV-HLKTAISELFFFLSGKNAETLTKNIGYGYAAGFLASRGIEI--PQDAN---EAFATNQ 397
                 **************************************99.*****************************************..55433...4467888 PP

        Ric8 395 kqakraiNPiTGqveeeee..enpleeMTeeEKErEAerLfvlfdr 438
                 ++ + a NPiTGq +++e+  ++p   MTeeEKErEAerLfvlf+r
  EEA21873.1 398 SNINPAFNPITGQRWDAEPqdTGP--AMTEEEKEREAERLFVLFER 441
                 899****************77777..*******************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (458 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       417  (0.0232584); expected 358.6 (0.02)
Passed bias filter:                      387  (0.0215851); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 2930.83
//
Query:       EEA21874.1  [L=438]
Description: MFS transporter (Mch2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-24   86.7  47.1    3.2e-24   85.5  47.1    1.5  1  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.5  47.1   1.8e-28   3.2e-24       2     351 ..      48     385 ..      46     386 .. 0.82

  Alignments for each domain:
  == domain 1  score: 85.5 bits;  conditional E-value: 1.8e-28
       MFS_1   2 llaaflsalarsilgpalplalaedlg......ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll.fasslw.lllvlr 92 
                 + +a+++a+a+++ +++   +la  l       +s   ++++ ++ +l+a++ ++++  l+   G + ++llg  l + g l+++ fa  +w l++   
  EEA21874.1  48 FGIAIINAFAWGVSSSFSV-YLAFYLDnnyfpgASSLGYSFVGGTNFLAALWVAPFVNILARHAGTKACMLLGSSLISGG-LVAAsFAREFWqLMITQG 144
                 6678899999999777777.5544444446666777778889999***********************999999999999.555559999********* PP

       MFS_1  93 vlqGlgagalfpagaaliadwfpkeergraigllsagfslGa.ilgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeeekg 190
                 ++ G+g g+lf + + +i++wf k +r++a g+ ++g+++G  i+ + +++++ ++++  ++  i +i++++ + l  +   +++++++  +pk+    
  EEA21874.1 145 IMVGAGVGFLFVSTVPIISQWFWK-KRSFAQGITAGGSGIGGlIFSASISPMI-QNISLAWALRIQGIICFVTLFL--ASTIVRDRNHHL-RPKQ---- 234
                 ************************.*****************55556666655.6*****************9553..333333333333.3323.... PP

       MFS_1 191 tgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaal 289
                    +p+      ++++  +w+lli ++l  +g+++ll+ lp +    lgls   +a+l   ll l+++ +++ ag++sdr+gr  +++  ++++++++l
  EEA21874.1 235 ---HPFDI---RFFRRWDVWLLLIWAFLYLLGYMTLLSSLPDF-IRSLGLS-PSEASLPAILLNLATITGRVGAGFVSDRYGR--ITIALISSIATGVL 323
                 ...34444...67778889955555555557***********9.*******.677777788888888888************9..88888888888888 PP

       MFS_1 290 glallavtssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfntagslggal 351
                 +l+++ +++s + +l++++++G  +++++p+++ la++ ++ ee  ++++++ ++ +l +++
  EEA21874.1 324 CLVFWIPSQSLAPTLVFSFIVGNVYSTIWPAIAPLAAEIVGLEELPSLLAIVWLTTGLPCFF 385
                 8888888888999999*************************999999999998888887776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (438 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       558  (0.0311228); expected 358.6 (0.02)
Passed bias filter:                      249  (0.0138881); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.32s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 2797.75
//
Query:       EEA21875.1  [L=388]
Description: hypothetical protein PMAA_056630 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.2e-07   30.0   2.9    7.3e-07   28.8   2.9    1.6  1  CorA      CorA-like Mg2+ transporter protein
  ------ inclusion threshold ------
      0.059   13.6   0.9       0.14   12.4   0.9    1.6  1  TadE      TadE-like protein


Domain annotation for each model (and alignments):
>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.8   2.9   8.2e-11   7.3e-07     104     289 ..     171     350 ..     153     353 .. 0.81

  Alignments for each domain:
  == domain 1  score: 28.8 bits;  conditional E-value: 8.2e-11
        CorA 104 kpkspgellyrlldeivdrlfellekleeeldeledel....edstkkeilrelaqlrrrlvklrralapnrevlkrllakaddkllddedkeylrdll 198
                  +    ++++  l++ + r+   l++ e++l   ++++     ds+k++ l++ + +  ++ k+rr + ++   + ++ a      +d++       ++
  EEA21875.1 171 STIFLRRIVISMLNSTLRRYYSDLSQHETKLWVMQRMIdpnlTDSEKNQYLGDFIGVMNEINKIRRRMIEHPYQIPSHRA------EDRDF-----IIR 258
                 5556678999999******************99999999999**************************999999966666......44444.....899 PP

        CorA 199 delerllemlealrerleslqdtyssllserlNrvmkvLTvltaiflPlTlitGiyGmNfkglPelewsygypfvll.lglmallailllfw 289
                 d++ +  +++e l + ++    ++ +  s    + +  LT+l  +f+P +++ +++ mN ++  +    ++y++v+l l+l++l+ ++  +w
  EEA21875.1 259 DKFLSYRKWSEKLLNITSAHLALMETEKSISDSKALSQLTILGSLFIPVSFVCSFFSMNGDFAVGETKFWVYFAVTLpLVLTILVIVFGRWW 350
                 9999999**9999999999999999999999****************************996665555555555544244444444444455 PP

>> TadE  TadE-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.9   1.6e-05      0.14       5      31 ..     329     353 ..     329     358 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 1.6e-05
        TadE   5 vEFALvlPlllllllgiiefgrylyar 31 
                 v FA+ lPl+l +l  +i fgr++y r
  EEA21875.1 329 VYFAVTLPLVLTIL--VIVFGRWWYRR 353
                 67******999988..8999****976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (388 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       675  (0.0376485); expected 358.6 (0.02)
Passed bias filter:                      510  (0.0284455); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 2534.42
//
Query:       EEA21876.1  [L=399]
Description: monocarboxylate permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-27   96.9  69.1      2e-23   82.9  45.1    2.0  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.9  45.1   1.1e-27     2e-23      33     352 ..      42     349 ..      27     350 .. 0.83
   2 !   27.8  16.1   6.3e-11   1.1e-06      53     174 ..     261     385 ..     259     398 .. 0.82

  Alignments for each domain:
  == domain 1  score: 82.9 bits;  conditional E-value: 1.1e-27
       MFS_1  33 eigllltlyalgaavaslplGrlsdrfGrrr.vlllglllfalglllllfasslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsag 129
                  i++++t+  ++ ++   ++Gr++d +G+r+ +l ++ll++++  ++ ++++ ++ ++l+  +  Glgag++f+++++ + +wf k +rg+a+g+  ag
  EEA21876.1  42 DISWIFTIQLALIWAPGSLFGRIVDTYGPRPvILPCSLLCMFSL-CMTSLSTKYYqIILAQGIGYGLGAGGIFTTSLVCVGQWFVK-QRGLAMGVTVAG 138
                 69*****************************5555555555555.4444778899899999************************9.************ PP

       MFS_1 130 fslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeeekgtgpaplvpawkallkdpvlwillialllfffgfsgllt 228
                 +s+G ++ p +  l+++ +g++++    a++  +a  l++ +++ +++ +++k +          ++++  k+++++ + + + ++++++++g+++ + 
  EEA21876.1 139 SSIGGVIFPFFLQLVMEDVGFPGMVRYTALFIGIA--LVGSFFLLSARLPAKKWDSNM-------AWFD-VKLFKNRGFAF-YALGSYFMMWGLWAPFD 226
                 ********************999999999999999..556777777777777655555.......8899.77777777554.66666666667778*** PP

       MFS_1 229 llplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllllvlvl.iGfglgfvfpsllalas 326
                 +lp+ + +  g++   la++l+a++ +++++++++ g + d++g  + ++ + ++  +a l+l l   ++s+ ++l+v+++ +Gf++g ++++++ +++
  EEA21876.1 227 FLPS-MAQLSGIP-DSLALYLIAIMNAASLFGRIIPGHIGDKVGYFNVIVASAFFSCIAILCLWLPFDYHSSNAGLIVFAVaYGFFSGAFVSIMMPCCA 323
                 ****.5*******.477777899999999999************86666666655555555555555556666666655556***************** PP

       MFS_1 327 dlappeeagtasglfntagslggalg 352
                 ++ + e  g+++g ++ + +++++ g
  EEA21876.1 324 KSGSIETLGRQIGTYQGVIAISTLTG 349
                 ****************9999998765 PP

  == domain 2  score: 27.8 bits;  conditional E-value: 6.3e-11
       MFS_1  53 GrlsdrfGrrrvlllglllfalglllllfa...sslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailg.pllgglla. 145
                 G+++d++G   v++++++++++++l+l+++   +s+   l+v+ v  G+++ga++++++   a+  + e  gr ig +++ ++++++ g p+ g++l  
  EEA21876.1 261 GHIGDKVGYFNVIVASAFFSCIAILCLWLPfdyHSSNaGLIVFAVAYGFFSGAFVSIMMPCCAKSGSIETLGRQIGTYQGVIAISTLTGlPIMGAILGt 359
                 889********************8888843457777779**************************************************6666666666 PP

       MFS_1 146 sslgWravfyilaivsllafvlfllllpe 174
                 ++ +    + ++ai++++++ l   +l++
  EEA21876.1 360 EHNSTYMGMQVFAIATMFLGFL---FLLV 385
                 6666666677777777777665...3332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (399 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       613  (0.0341904); expected 358.6 (0.02)
Passed bias filter:                      259  (0.0144459); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.23s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 2801.48
//
Query:       EEA21877.1  [L=1736]
Description: telomere length regulator protein (Rif1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   5.3e-137  456.8   1.5   5.3e-137  456.8   1.5    2.1  2  Rif1_N    Rap1-interacting factor 1 N terminal


Domain annotation for each model (and alignments):
>> Rif1_N  Rap1-interacting factor 1 N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  456.8   1.5    3e-141  5.3e-137       1     374 []     130     503 ..     130     503 .. 0.99
   2 ?   -0.8   0.1     0.033   5.8e+02      50      94 ..     598     643 ..     582     654 .. 0.79

  Alignments for each domain:
  == domain 1  score: 456.8 bits;  conditional E-value: 3e-141
                 ...........HHHHHS---BGGG....HHHHHHHHHHHHHHHHHHHTSSSSS---HH..HHHHHHHHHHHHHSSHHHHHHHTTHHHTHHHHHHTTTTT CS
      Rif1_N   1 lagsdrssrlDaYmtLlraLkasdnlpdrkalqkkmslllqfiqrDisssssekgnldssLviqAlkllgtllsnpaiastLsddfkvfiidhsirsle 99 
                 lag++ ssr+DaYm+Ll+aLka+dn+++++ +++k+++llqf+qrDis++  + + ++++Lv++Alkl  ++++++++as+++ddfk+fiidh++++l+
  EEA21877.1 130 LAGESLSSRVDAYMQLLGALKAYDNISEQEDMSSKVGILLQFVQRDISRDLGKGDVVETNLVTNALKLGIYIIWSQQLASQIPDDFKIFIIDHALSVLQ 228
                 7999************************************************99999****************************************** PP

                 STT--HHHHHHHHHHHHH--THHHHS-HHHHHHHHTTCCS--.----HHHHHHHHHHHHHHHHHSHHHHHHTHHHHHHHHHHHHHHHHHTTT-HHHHHT CS
      Rif1_N 100 dsstpKniithllsvlsqQkFsskimtservkrllsalenieervkgksiiaerlniyrrLleqapslmlahaelWlpdlfsgllssvkdirekaiqlg 198
                 + + +K+i++h++++l +Q+Fs+k+mt++r++r+l++l++i++rv+g+ ii++rl +y+rLl q++ +m+++a+lW+++l+sgll+ vkd+r+ka+ lg
  EEA21877.1 229 EGKFSKAILNHYVHILYTQNFSAKVMTNSRITRVLAVLNDITDRVNGNGIISQRLGVYTRLLGQSKTVMASQASLWVEHLISGLLHPVKDTRSKALVLG 327
                 *************************************************************************************************** PP

                 TSBHHHHS-HHHHTTS---SHHHH-TTT-BHHHHHHHHHHHHHHTT--HHHHHHHHHHHHHHHH-STTGGGGSHHHHHHHHHHHHHHTTS-HHHHHHHH CS
      Rif1_N 199 leaalalgkekevskavlelldseleegktlievlierLkkmlkekknekivpqiWsvvilLlrkkrkslesweffnewLkliqkcFnssdpevkieAn 297
                  ++al lg++  +sk++l+++++e++eg++l++++++r+++m++  +++++vpqiWs+++lLlr+kr+++e+we+f+ew+ ++q+cFn+s++++k +A+
  EEA21877.1 328 NQTALVLGPNIVISKTILDIFNKEISEGRKLVSEICDRMSRMMSPSDSGVHVPQIWSIIVLLLRSKRFNIEHWEYFKEWVLVLQRCFNCSESAIKSQAI 426
                 *************************************************************************************************** PP

                 HTTHHHHHHHHHS--TT-HHHHHTTHHH........HHHTSHHHHHHHHHHHHHHHHHHHTT-TTTHHHHHTTTTTH CS
      Rif1_N 298 iaWnrliyavnpdestskkllklLrqPllsqlerkkesksakelreavlsslcnllyyalrplasakqldlvWdevv 374
                 i Wn+++y+v  +ests+++lk+L++P+ls+ erk+++k   +++ + lss++nllyy++rp+++++++d++W+e++
  EEA21877.1 427 IGWNKFVYMVTCNESTSRSMLKMLTRPILSNSERKRSDKAGTSANPLFLSSYYNLLYYSFRPNNPFDHIDFIWEEYI 503
                 ***************************************************************************96 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.033
                 SSSS---HH..HHHHHHHHHHHHHSSHHHH.HHHTTHHHTHHHHHH CS
      Rif1_N  50 sssekgnldssLviqAlkllgtllsnpaia.stLsddfkvfiidhs 94 
                 +ss++ ++ s+L++++ ++lg++ +  + + s+L++d++  +i++ 
  EEA21877.1 598 ASSKEIKPSSELMHAIATILGFFQRLRQTSpSSLNTDKGDIFIERF 643
                 44556678999*************9988874789999999999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1736 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       783  (0.0436723); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.96u 0.29s 00:00:01.25 Elapsed: 00:00:00.46
# Mc/sec: 11286.79
//
Query:       EEA21878.1  [L=512]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (512 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       562  (0.0313459); expected 358.6 (0.02)
Passed bias filter:                      485  (0.0270511); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.41
# Mc/sec: 3787.34
//
Query:       EEA21879.1  [L=169]
Description: hypothetical protein PMAA_056670 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.4e-06   26.0  14.9    1.4e-05   25.1  14.9    1.5  1  bZIP_1           bZIP transcription factor
     0.0007   20.1   7.6      0.001   19.6   7.6    1.3  1  bZIP_Maf         bZIP Maf transcription factor
  ------ inclusion threshold ------
      0.018   14.9   0.4      0.026   14.4   0.4    1.3  1  Glutaredoxin2_C  Glutaredoxin 2, C terminal domain
      0.027   14.1   0.4      0.052   13.2   0.4    1.5  1  Vac_Fusion       Chordopoxvirus multifunctional envelope prot
      0.052   13.3   0.6      0.058   13.2   0.6    1.1  1  AAA_11           AAA domain
      0.059   12.6   5.7        1.6    7.8   0.3    2.1  2  7tm_7            7tm Chemosensory receptor
      0.063   13.3   2.4      0.086   12.8   2.4    1.1  1  DUF2400          Protein of unknown function (DUF2400)
      0.068   14.2   3.9        0.1   13.6   3.9    1.2  1  Spt5_N           Spt5 transcription elongation factor, acidic
       0.07   13.8   1.2       0.07   13.8   1.2    1.6  2  SlyX             SlyX
      0.081   11.4   2.3        0.1   11.1   2.3    1.1  1  Baculo_F         Baculovirus F protein
       0.14   12.2   5.0       0.18   11.9   5.0    1.1  1  UPF0242          Uncharacterised protein family (UPF0242) N-t
       0.25   10.7   2.0       0.33   10.3   2.0    1.1  1  DUF4407          Domain of unknown function (DUF4407)
       0.27   11.3  17.0       0.76    9.9  17.0    1.8  1  bZIP_2           Basic region leucine zipper
       0.74   10.0   4.5       0.99    9.6   4.5    1.1  1  Fib_alpha        Fibrinogen alpha/beta chain family
       0.81    9.5   7.9        3.5    7.5   4.6    2.1  2  DivIC            Septum formation initiator
        1.4    8.6   3.6        2.7    7.7   3.6    1.4  1  EMC3_TMCO1       Integral membrane protein EMC3/TMCO1-like


Domain annotation for each model (and alignments):
>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1  14.9   1.2e-08   1.4e-05       6      50 ..      93     137 ..      89     157 .. 0.85

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 1.2e-08
                 XXXXX--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1   6 rekrkqkNReaArrsRqRKqaeieeLerrvkaLekeNksLksele 50 
                 r +r+++NR a+r++R+RK+++ + Le++ ++L+k   +L++   
  EEA21879.1  93 RMRRREQNRAAQRAYRERKEKSFKSLEEKLSKLQKRYDELAKLYT 137
                 89********************************99998887555 PP

>> bZIP_Maf  bZIP Maf transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   7.6   8.9e-07     0.001      21      79 ..      83     141 ..      77     165 .. 0.86

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 8.9e-07
    bZIP_Maf  21 lteeeverLKqrRRrlKNrgyakscrkrrlqqkeelekekeeleeelerlqqelsrlrq 79 
                 l e   +++ + RRr +Nr +++  r+r+ +  ++le++ ++l+++ ++l++ ++  ++
  EEA21879.1  83 LMESSSTDIMRMRRREQNRAAQRAYRERKEKSFKSLEEKLSKLQKRYDELAKLYTDKER 141
                 55666788999************************************999987665555 PP

>> Glutaredoxin2_C  Glutaredoxin 2, C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.4   2.3e-05     0.026      31      75 ..     100     144 ..      91     162 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 2.3e-05
  Glutaredoxin2_C  31 tqsAreyftkkkeksigdfeellaktpeliaelnalLeeleplik 75 
                       ++A+++++++keks++++ee l+k ++ + el +l ++ e  i+
       EEA21879.1 100 NRAAQRAYRERKEKSFKSLEEKLSKLQKRYDELAKLYTDKERTIN 144
                      5789**********************9999999988777777664 PP

>> Vac_Fusion  Chordopoxvirus multifunctional envelope protein A27
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.4   4.6e-05     0.052       2      34 ..     115     147 ..     114     150 .. 0.95

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 4.6e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Vac_Fusion   2 lkdleerllvlekdfqlvikcckrvnealkRlE 34 
                 +k+lee+l +l+k + +++k +  ++  ++Rl 
  EEA21879.1 115 FKSLEEKLSKLQKRYDELAKLYTDKERTINRLN 147
                 799****************************96 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.6   5.2e-05     0.058     122     189 ..      77     144 ..      39     156 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 5.2e-05
      AAA_11 122 kaqlakeiskeleklakelrafeeeeekeklkkskekskskleqerrklkkerkelskeleeaeesle 189
                 +++ ++ +++++ +++++ r +++ +++++ ++ keks ++le++++kl+k  +el k ++ +e++++
  EEA21879.1  77 DNNRMHLMESSSTDIMRMRRREQNRAAQRAYRERKEKSFKSLEEKLSKLQKRYDELAKLYTDKERTIN 144
                 67778999999999999999999999999999999999999999999999999999999999999886 PP

>> 7tm_7  7tm Chemosensory receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   0.3    0.0014       1.6     156     196 ..       2      42 ..       1      46 [. 0.86
   2 ?    7.5   0.8    0.0019       2.1     184     232 ..      81     138 ..      78     156 .. 0.64

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0014
       7tm_7 156 lllyllpylvlqlllllyfllllliyellrllnerLkqlvr 196
                 +++ +l+   +++ +++y++ll+l + +++ l +++ ql+ 
  EEA21879.1   2 NWTSTLFVRGMNHNFSMYYVLLGLANSVYNSLDIQFGQLTS 42 
                 55666666689*************************99976 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0019
       7tm_7 184 lrllnerLkqlvrelrgrseseq.....flreqslla....lrellrlyrrlselvre 232
                 ++l+ +  +++ r  r+++++        ++e s+ +    l++l+++y++l++l+  
  EEA21879.1  81 MHLMESSSTDIMRMRRREQNRAAqrayrERKEKSFKSleekLSKLQKRYDELAKLYTD 138
                 55555555555555444444444666655555555559999*************9865 PP

>> DUF2400  Protein of unknown function (DUF2400)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   2.4   7.7e-05     0.086      41     120 ..      81     158 ..      75     168 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 7.7e-05
     DUF2400  41 lelmdkspydfvleeeeekdlkelekfkyRffnsedllallkalkelleksgsLeeaflkaeeeeeeleealeafreafl 120
                 ++lm++s +d+++ ++ e++ +   +  yR  +++++++l + l++l ++++ L ++++++e++ ++l++ + +++ ++ 
  EEA21879.1  81 MHLMESSSTDIMRMRRREQN-RA-AQRAYRERKEKSFKSLEEKLSKLQKRYDELAKLYTDKERTINRLNQMIMSLILEIP 158
                 68999999999997774433.33.3446*******************************987777777777777665554 PP

>> Spt5_N  Spt5 transcription elongation factor, acidic N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   3.9   8.9e-05       0.1      16      88 ..      71     142 ..      62     153 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 8.9e-05
                 XXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
      Spt5_N  16 eeeeeveggeddfiaeeeaeeeeedserddrshreldrrrqaeededaeeiaealeeRYgrsskkayrgeaee 88 
                 ++  +++  ++  +++   +    ++++++r+ ++  r+r++++++++ee   +l++RY +  +k y++++ +
  EEA21879.1  71 NSSGDADNNRMHLMESSSTDIMRMRRREQNRAAQRAYRERKEKSFKSLEEKLSKLQKRYDE-LAKLYTDKERT 142
                 455566666666555555555555566677777777788888888**************88.77777766555 PP

>> SlyX  SlyX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       5.4   6.1e+03      38      44 ..      98     104 ..      86     117 .. 0.51
   2 ?   13.8   1.2   6.2e-05      0.07       3      55 ..     113     165 ..     111     168 .. 0.87

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 5.4
                 HHHHHHH CS
        SlyX  38 rqlrlla 44 
                 +q r+ +
  EEA21879.1  98 EQNRAAQ 104
                 2222222 PP

  == domain 2  score: 13.8 bits;  conditional E-value: 6.2e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT-XXXXXXXX CS
        SlyX   3 erleeLEiklafqedtieeLndvvaeqqqqidrlqrqlrllaerlkeleessg 55 
                 + ++ LE+kl+ +++  +eL +  ++ +++i rl + +  l  ++ +l+++++
  EEA21879.1 113 KSFKSLEEKLSKLQKRYDELAKLYTDKERTINRLNQMIMSLILEIPALRNEKE 165
                 56789******************************999999888888877655 PP

>> Baculo_F  Baculovirus F protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   2.3     9e-05       0.1     176     253 ..      78     152 ..      72     165 .. 0.64

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 9e-05
    Baculo_F 176 nslneqvkqltdeliklseyveskkqeieeq..kedkCeyieaklnllkdqldeieslytkldravddAlknklsslilt 253
                 n++++ + + +++ +++ +  +++ ++   +  ke++ +++e+kl+ l++ +de+++lyt  +r ++     +l+++i++
  EEA21879.1  78 NNRMHLMESSSTDIMRMRRREQNRAAQRAYRerKEKSFKSLEEKLSKLQKRYDELAKLYTDKERTIN-----RLNQMIMS 152
                 4555555555555555555555443322222347888999999999999999999999999988885.....55555553 PP

>> UPF0242  Uncharacterised protein family (UPF0242) N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   5.0   0.00016      0.18      69     125 ..      99     156 ..      78     167 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00016
     UPF0242  69 kleekeaklteld.eglktkeealeelqeeeeeLkeeldakeeelerlkeenqqLqek 125
                 ++ + ++   e + +++k  ee+l +lq++ +eL++ +  ke++++rl++   +L  +
  EEA21879.1  99 QNRAAQRAYRERKeKSFKSLEEKLSKLQKRYDELAKLYTDKERTINRLNQMIMSLILE 156
                 3334444444444368********************************9987777655 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   2.0   0.00029      0.33     114     165 ..      94     145 ..      84     155 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00029
     DUF4407 114 eeqqeeakelkeqlaaaltaelaeleaqiaalqaeidaaearldalraeaqk 165
                  +++e+++++++ +++  ++  + le+++++lq+ +d++ + +++++++ ++
  EEA21879.1  94 MRRREQNRAAQRAYRERKEKSFKSLEEKLSKLQKRYDELAKLYTDKERTINR 145
                 4677888888999999988999999999999999999999988888887764 PP

>> bZIP_2  Basic region leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9  17.0   0.00068      0.76       6      44 ..      93     132 ..      88     163 .. 0.89

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00068
                 XXXXX.XXXXXXXX-HHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_2   6 rerRr.kNreAarrsRekkkakeeeleervkeLeeeNaqL 44 
                 r rRr +Nr+A r +Re+k +  ++lee++ +L+++ ++L
  EEA21879.1  93 RMRRReQNRAAQRAYRERKEKSFKSLEEKLSKLQKRYDEL 132
                 567777*****************************98888 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   4.5   0.00088      0.99      55     128 ..      77     153 ..      67     156 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00088
                 HHHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  55 eelvkeikdslre...kqkskkdndnvikksskeleeeilrlketidaqesnirvLqnvlesneqkiqkLeqdidqk 128
                 ++   ++++s      + +  ++n  + + ++++ e+    l+e++++  ++  +L +++ ++e+ i++L+q i+++
  EEA21879.1  77 DNNRMHLMESSSTdimRMRRREQNRAAQRAYRERKEKSFKSLEEKLSKLQKRYDELAKLYTDKERTINRLNQMIMSL 153
                 444444444443311123334445777888999999999**********************************9987 PP

>> DivIC  Septum formation initiator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   4.6    0.0031       3.5      16      59 ..      91     134 ..      87     135 .. 0.92
   2 ?    4.7   0.2     0.022        25      19      56 ..     129     166 ..     128     167 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0031
                 XXHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC-XXXXXXXXX CS
       DivIC  16 llaykqlkqeiaalqaelaklkaeneeLeaevkdLksdedyiee 59 
                 ++++++ +q++aa+ a  +++ +  ++Le+++++L++ +d +++
  EEA21879.1  91 IMRMRRREQNRAAQRAYRERKEKSFKSLEEKLSKLQKRYDELAK 134
                 89999******************************999999876 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.022
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC-XXXXXX CS
       DivIC  19 ykqlkqeiaalqaelaklkaeneeLeaevkdLksdedy 56 
                 y +l + ++++++++++l++ +++L  e+  L++++++
  EEA21879.1 129 YDELAKLYTDKERTINRLNQMIMSLILEIPALRNEKEA 166
                 666777788999******************99988875 PP

>> EMC3_TMCO1  Integral membrane protein EMC3/TMCO1-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   3.6    0.0024       2.7      45     104 ..      90     158 ..      78     160 .. 0.63

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0024
  EMC3_TMCO1  45 ekeqkrekelqkrarelqkngdklklkklekrqeelmedqsem............mmdqmkpmivtmipqil 104
                 + +++r +e  ++a+++ +++   k+k++++ +e+l + q+              + + + +mi+ +i+ i+
  EEA21879.1  90 DIMRMRRREQNRAAQRAYRER---KEKSFKSLEEKLSKLQKRYdelaklytdkerTINRLNQMIMSLILEIP 158
                 444455555555555555555...555555555555555555555599999999999999999999999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (169 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1978  (0.110324); expected 358.6 (0.02)
Passed bias filter:                      866  (0.0483016); expected 358.6 (0.02)
Passed Vit filter:                       145  (0.00808746); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              16  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 1165.85
//
Query:       EEA21880.1  [L=395]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    8.5e-05   22.4   5.4    0.00022   21.0   5.4    1.7  1  PAN_4       PAN domain
    0.00084   19.3   1.2     0.0037   17.2   1.2    2.1  1  PAN_1       PAN domain


Domain annotation for each model (and alignments):
>> PAN_4  PAN domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0   5.4   2.5e-08   0.00022       6      39 ..     320     352 ..     315     366 .. 0.74

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 2.5e-08
       PAN_4   6 ndlangevladspeaCcaaCaadsnCn.awvyvkp 39 
                 +d      +++sp++Cc aC++++ C+  +++ ++
  EEA21880.1 320 QDFVV--ASVSSPYDCCVACQQNPACAfTYSFAYN 352
                 55444..499****************985555553 PP

>> PAN_1  PAN domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   1.2   4.1e-07    0.0037      13      58 ..     319     371 ..     307     387 .. 0.75

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 4.1e-07
                 SEEEEEEECSSHHHHHHHHHHSTTS--S...EEEEETT......TTEEEEEESSS CS
       PAN_1  13 gedkktitvdsaeeCaerCseekkfrCr...sftfnns......tkeCylksedk 58 
                 g+d  +  v+s+ +C+ +C++++   C    sf +n+s      t+ C  k++ +
  EEA21880.1 319 GQDFVVASVSSPYDCCVACQQNPA--CAftySFAYNPSychivlTNSCSSKTHGT 371
                 35666669****************..*7544678888888888888888776544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (395 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1187  (0.0662056); expected 358.6 (0.02)
Passed bias filter:                      309  (0.0172346); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.30s 00:00:00.86 Elapsed: 00:00:00.43
# Mc/sec: 2729.28
//
Query:       EEA21881.1  [L=373]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.7e-10   41.2   0.0    3.7e-10   40.8   0.0    1.2  1  Abhydrolase_6  Alpha/beta hydrolase family
    1.1e-08   34.7   0.0    2.6e-08   33.4   0.0    1.6  1  Hydrolase_4    Serine aminopeptidase, S33
    9.1e-06   25.5   0.5    4.6e-05   23.2   0.2    2.3  3  Abhydrolase_1  alpha/beta hydrolase fold
     0.0041   16.9   0.2      0.022   14.5   0.3    2.2  2  PGAP1          PGAP1-like protein
     0.0072   15.8   0.0        1.8    8.0   0.0    2.5  3  Peptidase_S9   Prolyl oligopeptidase family
  ------ inclusion threshold ------
      0.081   12.6   0.3        1.6    8.3   0.1    2.2  2  ComK           ComK protein


Domain annotation for each model (and alignments):
>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.8   0.0   1.2e-13   3.7e-10       1     211 [.     102     356 ..     102     367 .. 0.59

  Alignments for each domain:
  == domain 1  score: 40.8 bits;  conditional E-value: 1.2e-13
                    EEEE.--GC.....G.....C..HHHHHHHHCCTCEEEEE--TTSTS-GGCS--HHHCHHH.HHHHCCTT..............TTSEEEEEETCH CS
  Abhydrolase_6   1 vlll.HGagssassW.....l..vapLaallaagvhvlapDlpGhGrsdpppldledladl.aalldelaa............gggpvvlvGHSlG 75 
                    vl++ HG+ ++ + W        ++++ ++ ++g+ ++ +D+ G G ++++  ++++ + +  ++++ l+              ++  v+vGHS+G
     EEA21881.1 102 VLFAtHGLNFDNRYWaseiqPdnYSFVDYAINRGYSIFYYDRLGVG-ASTKVSGYTNQLPIqIEIATQLIIsiksskytgslgKPDSLVVVGHSFG 196
                    57777**********877641556677888888877799*******.99******995444555555554446669999987666666******** PP

                    HHHHHHHHHCC....EEEEES-..----TTTS----TTHHHHHHTT-CCCCHCCH..........S-HSCCCCHHHCCCCHCHCCCGHHHHCCHHC CS
  Abhydrolase_6  76 Galalaaapla..lvvgvlldppptalpagllaaalelllallallrllawlsre..........plprlfladedadaawrarlarlaallaglg 159
                     a+++ ++++   +  +++l +   ++  +++  ++e ++ ++a+  +++w++++          +   +f++++d    +  ++ r a++ +++ 
     EEA21881.1 197 SAISAGTVAANpeICDALILTG--FSYNGSNPVGFVEAAQLRIASSEDPRWRKLDtgyllpvdiySNVNTFFKKPD----YDLNVVRYADSIKQPL 286
                    9988885555544333355555..3444444555555555555555558888655555544443333336666666....4444444444444333 PP

                    ...........HTTCCHHTT-TTGC.....EEEC..TT-C..HHHHCHHCCCH.STTEEETCE...SSS-HHH CS
  Abhydrolase_6 160 ...........llpaaawadlpvpl.....lvlg..geDp..lvprllerlla.qagarlpvvlpgaGHlphl 211
                                l+++++++  + +     ++++    D+   +p  ++   a + +++  + +pgaGH +++
     EEA21881.1 287 glvevltgassNLSPSEFTGKAMVIagqydFIFCtgQCDDviEYP--AANVFAkAKDFKA-ISYPGAGHGLNF 356
                    221122122111123344444444466655455455556645555..5566665666666.99******6665 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.4   0.0   8.8e-12   2.6e-08      24     234 ..     128     354 ..     124     357 .. 0.77

  Alignments for each domain:
  == domain 1  score: 33.4 bits;  conditional E-value: 8.8e-12
  Hydrolase_4  24 aeaLaaqGfavyalDhrGhGrsegkrghvpsfddyvdDlaafvekvk.eehpel.....plfllGhSmGGliallyllrypdkvaglilsaPalkika 115
                  +++  ++G++++ +D  G G s    g+ +++   ++ + +++  +k +++ ++      l+++GhS G++i++  ++ +p+ +++lil++  ++  +
   EEA21881.1 128 VDYAINRGYSIFYYDRLGVGASTKVSGYTNQLPIQIEIATQLIISIKsSKYTGSlgkpdSLVVVGHSFGSAISAGTVAANPEICDALILTGFSYNGSN 225
                  5666789****************99*******9999999999988885555555888899**********************999**********999 PP

  Hydrolase_4 116 klk.appllklllkllgkllpklqvsnnlkadslsrdpevvaayeadplv.hgkitvrlllelldamkrleeraakit...........lPllllhGe 200
                  ++  + +++  ++    + ++kl     l  d  s+ + + ++ + d  v + + +++  l+l++++  + ++ +  +           + +++  G+
   EEA21881.1 226 PVGfVEAAQLRIASSEDPRWRKLDTGYLLPVDIYSNVNTFFKKPDYDLNVvRYADSIKQPLGLVEVLTGASSNLSPSEftgkamviagqYDFIFCTGQ 323
                  98766666666777777777777776666666667777888888888888777888888888888887777776655544444444455556666666 PP

  Hydrolase_4 201 aDkvvdpeasrelyerlgskdktlklypglyHel 234
                   D v+++ a+ +++++++  d +   ypg+ H l
   EEA21881.1 324 CDDVIEYPAA-NVFAKAK--DFKAISYPGAGHGL 354
                  6666665555.5555555..78999999999976 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0         2   5.9e+03     106     131 ..      22      50 ..      14      53 .. 0.75
   2 !   23.2   0.2   1.5e-08   4.6e-05      20     121 ..     127     238 ..     107     250 .. 0.82
   3 ?   -2.9   0.0       1.4   4.3e+03     156     156 ..     294     294 ..     261     325 .. 0.53

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 2
                    E...CSSCCHHHHHHHHHHHHHHCHHCHH CS
  Abhydrolase_1 106 a...idpaaslieaqrqqaksfpdffdgy 131
                    +    ++++ l  + ++ ++ +p+f+d+y
     EEA21881.1  22 TkvcQNYKIPLTVTSENFVYDMPYFADNY 50 
                    25555778888888999999999999998 PP

  == domain 2  score: 23.2 bits;  conditional E-value: 1.5e-08
                    HHHHHHHHTTSEEEEEEETTSTTSSSTTTGB..........CHHSHHHHHHHHHHHHHHCTTSSEEEEEETHHHHHHHHHHHHHGGGEEEEEEESE CS
  Abhydrolase_1  20 glapaLakdgfdvillDlrGvgySspapacin.........ddygtasvaddldrildalgddkltlvGhSmGGmialayaaeyperVkalvllga 106
                    ++ +a+++ g+ ++ +D +Gvg S++ +   n         ++  +    ++ ++     + d+l++vGhS+G++i++   a +pe ++al+l+g 
     EEA21881.1 127 FVDYAINR-GYSIFYYDRLGVGASTKVSGYTNqlpiqieiaTQLII--SIKSSKYTGSLGKPDSLVVVGHSFGSAISAGTVAANPEICDALILTGF 219
                    46677777.9999999999999999999887778777776655555..67777788999999********************************99 PP

                    ....CSSCCHHHHHHHHHH CS
  Abhydrolase_1 107 ....idpaaslieaqrqqa 121
                        ++p    + aq+++a
     EEA21881.1 220 syngSNPVGFVEAAQLRIA 238
                    8877777777776666666 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 1.4
                    H CS
  Abhydrolase_1 156 r 156
                     
     EEA21881.1 294 G 294
                    1 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.3   7.3e-06     0.022      62     109 ..     156     204 ..      95     218 .. 0.85
   2 ?   -1.6   0.0      0.62   1.8e+03     142     199 ..     257     321 ..     254     329 .. 0.67

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 7.3e-06
       PGAP1  62 GrtlldqaeylndaIkyIls.lysssekeptsviliGHSmGGivaraal 109
                  ++l  q+e   ++I  I s  y+ s  +p s++++GHS+G  ++  ++
  EEA21881.1 156 TNQLPIQIEIATQLIISIKSsKYTGSLGKPDSLVVVGHSFGSAISAGTV 204
                 5778889999999999997526999****************99986555 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.62
       PGAP1 142 klyervnefwkkeleekek.......lenvllvsitggirdsmvpaeyssleelvpstnglsvat 199
                 ++y++vn+f+kk   + +         + + lv + +g +  + p+e++    ++  + ++   t
  EEA21881.1 257 DIYSNVNTFFKKPDYDLNVvryadsiKQPLGLVEVLTGASSNLSPSEFTGKAMVIAGQYDFIFCT 321
                 68999999988764333334454555667788888888888888888887666666666666555 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0       1.3     4e+03      98     133 ..      52      85 ..      44     118 .. 0.45
   2 !    5.2   0.0    0.0043        13      61     107 ..     183     229 ..     167     276 .. 0.72
   3 !    8.0   0.0    0.0006       1.8     148     207 ..     319     373 .]     293     373 .] 0.73

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 1.3
                   ---CCCHHCSTTSTHH.HCCCC--TTTCHHHHHHHHH CS
  Peptidase_S9  98 vvdvlrydsdtdllte.eymewgnpeeneegykelsp 133
                   vvd+++   +    +   y  + n ++n++  ++  +
    EEA21881.1  52 VVDWISNFGSR--TASvDYHPFSNTKQNQT-ASYTIS 85 
                   55666555553..22223333333322222.222222 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0043
                   --GGGEEEEEETHHHHHHHHHHHH-GGG-SEEEEESE---CCCHHCS CS
  Peptidase_S9  61 vdserlaitGgSyGGyltgaalnqrpdlFkaavaevpvvdvlrydsd 107
                    +++ l++ G+S+G   ++ +++ +p++ +a++     ++  +   +
    EEA21881.1 183 GKPDSLVVVGHSFGSAISAGTVAANPEICDALILTGFSYNGSNPVGF 229
                   57899**************999999*999998887766666655555 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.0006
                   EEEETT-SSS-THHHHHHHHHHH--S-SEEEEEETTS-SSTTSSHHHHHHHHHHHHHHHH CS
  Peptidase_S9 148 lihGlaDdrvppaealklvaaLqkkgknvlllifpdegHgvgkprakveelarllaFlke 207
                   +++G+ Dd + +  a     ++  k k+++   +p++gHg++   +    +a++++Fl++
    EEA21881.1 319 FCTGQCDDVIEYPAA-----NVFAKAKDFKAISYPGAGHGLNFALNATGAYAEIFDFLEK 373
                   444444444444333.....33366799*****************************975 PP

>> ComK  ComK protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   0.1   0.00054       1.6      46     101 ..       6      59 ..       1      83 [. 0.85
   2 ?    1.9   0.0      0.05   1.5e+02      61      82 ..     148     169 ..     134     174 .. 0.89

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00054
        ComK  46 kScryygssyegrkegtkevlgikskvPivieptkniyfFPtkSpsreeciWisls 101
                  S+ ++ ss+  + ++tk     + k P ++++++ +y  P ++++ +   Wis  
  EEA21881.1   6 LSLATFTSSITFASAATKVCQ--NYKIPLTVTSENFVYDMPYFADNYDVVDWISNF 59 
                 688999999999999988665..579***************************965 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.05
        ComK  61 gtkevlgikskvPivieptkni 82 
                 ++ +v g++++ Pi ie ++++
  EEA21881.1 148 ASTKVSGYTNQLPIQIEIATQL 169
                 56799************99887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (373 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       388  (0.0216409); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.47
# Mc/sec: 2398.35
//
Query:       EEA21882.1  [L=301]
Description: alpha/beta hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.5e-13   48.4   0.0    2.3e-10   40.6   0.0    2.1  2  Abhydrolase_1  alpha/beta hydrolase fold
    2.1e-09   38.3   0.0    2.6e-09   38.0   0.0    1.1  1  Abhydrolase_6  Alpha/beta hydrolase family
    9.4e-08   31.6   0.0    7.5e-07   28.7   0.0    2.0  1  Hydrolase_4    Serine aminopeptidase, S33
    3.9e-05   22.5   0.0    5.9e-05   21.9   0.0    1.2  1  Ndr            Ndr family
  ------ inclusion threshold ------
      0.034   14.1   0.0       0.87    9.5   0.0    2.4  3  BAAT_C         BAAT / Acyl-CoA thioester hydrolase C terminal


Domain annotation for each model (and alignments):
>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.6   0.0   6.4e-14   2.3e-10      29     120 ..      59     151 ..      33     165 .. 0.81
   2 !    5.8   0.0    0.0026       9.5     183     247 ..     196     273 ..     188     280 .. 0.71

  Alignments for each domain:
  == domain 1  score: 40.6 bits;  conditional E-value: 6.4e-14
                    TSEEEEEEETTSTTSSSTTTGB.CHHSHHHHHHHHHHHHHHCTTSSEEEEEETHHHHHHHHHHHHHGGGEEEEEEESE.....CSSCCHHHHHHHH CS
  Abhydrolase_1  29 gfdvillDlrGvgySspapacinddygtasvaddldrildalgddkltlvGhSmGGmialayaaeyperVkalvllga.....idpaaslieaqrq 119
                       ++++ ++G+g ++ a+    ++++ ++ a    ++ d+lg++k   +G S+GG i++ +a+++p+++ +l+llg+     ++++ +l+++++ 
     EEA21882.1  59 AMNLLAIEPLGHGGTTCAS----EHFTYWDSAQTALQVIDKLGIQKAFALGVSQGGWIVTRMALLAPDKILGLMLLGTsldseSPESRDLGSWNPS 150
                    6678899999999999999....68*****************************************************655555555555555544 PP

                    H CS
  Abhydrolase_1 120 q 120
                    q
     EEA21882.1 151 Q 151
                    4 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0026
                    HHHHHHHHHHHHCCHHHHHHHHHC...........THHHHSEEEEEEETTCSSSCH.HHHHHHHHCHTS.EEEEEEET CS
  Abhydrolase_1 183 tgalksieqwpttdsaklllrlre...........lknvlaptlvisgtsDplvpp.kaledlaqllpk.krlvvisd 247
                    ++ ++++++++ + s+k+ ++  +           +k++ +p+ +++gt+D ++      + +++l++  +++++i++
     EEA21882.1 196 FWTKNFKDTYKGDESRKKVRMALIcllerdglllrVKDIACPVHWLQGTDDYIFGTkLPADHITRLTSAkETELTIVP 273
                    5667777777777777777777779999999********************999763334444444333344444444 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.0   0.0   7.4e-13   2.6e-09      24     220 .]      57     290 ..      35     290 .. 0.58

  Alignments for each domain:
  == domain 1  score: 38.0 bits;  conditional E-value: 7.4e-13
                    CCTCEEEEE--TTSTS-GGCS...--HHHCHHHHHHHCCTT..TTSEEEEEETCHHHHHHHHHHCC....EEEEES-..----TTTS----TTHHH CS
  Abhydrolase_6  24 aagvhvlapDlpGhGrsdppp...ldledladlaalldelaagggpvvlvGHSlGGalalaaapla..lvvgvlldppptalpagllaaalellla 114
                    ++    la+   GhG+++++    + ++ +++ ++++d+l+    +++++G S+GG+++++ a la   + g++l +++  +  +  ++ l  + +
     EEA21882.1  57 TDAMNLLAIEPLGHGGTTCASehfTYWDSAQTALQVIDKLG--IQKAFALGVSQGGWIVTRMALLApdKILGLMLLGTS-LDSESPESRDLGSWNP 149
                    555444899999**8675555233666668888*******6..9999**************444447766664444411.2222223333333333 PP

                    HHHTT-C.CCCHCCH...................S-HSCCCCHHHCCCCHCHCCCGHH...........HHCCHHC.HTTCCHHTT-TTGCEEECT CS
  Abhydrolase_6 115 llallrl.lawlsre...................plprlfladedadaawrarlarla...........allaglg.llpaaawadlpvpllvlgg 178
                       ll++ ++w++ +                    +++ + +++   + w+ ++ +             al + l+    + +++d+ +p+++l g
     EEA21882.1 150 SQLLLPFyDGWSAQKetpgfviddawcgafagvgGFGPNITPET--VEFWTKNFKDTYkgdesrkkvrmALICLLErDGLLLRVKDIACPVHWLQG 243
                    33333333455544422222211123332222221222222222..466666665555444444433333333333322366*********98856 PP

                    T-C.....HHHHCHHCCCH...STTEEETCE...SSS-HHHHSHHHHHHH CS
  Abhydrolase_6 179 eDp.....lvprllerlla...qagarlpvvlpgaGHlphleepdevaea 220
                    +D+      +p  ++++ +   +   +l +++pg+ H+++ ++p ev++a
     EEA21882.1 244 TDDyifgtKLP--ADHITRltsAKETEL-TIVPGGAHYLNTSSPGEVNAA 290
                    66669999666..444444433444555.***************999875 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.7   0.0   2.1e-10   7.5e-07      34     234 ..      62     279 ..      29     282 .. 0.75

  Alignments for each domain:
  == domain 1  score: 28.7 bits;  conditional E-value: 2.1e-10
  Hydrolase_4  34 vyalDhrGhGrsegkrghvpsfddyvdDlaafvekvkeehpelplfllGhSmGGliallyllrypdkvaglilsaPalkikaklkappllkl.llkll 130
                   +a+   GhG +  +  h++ +d+     a+   +v ++ + ++ f lG S GG i+++++l  pdk+ gl+l ++ l+ +++   + l  +  ++ll
   EEA21882.1  62 LLAIEPLGHGGTTCASEHFTYWDS-----AQTALQVIDKLGIQKAFALGVSQGGWIVTRMALLAPDKILGLMLLGTSLDSESPE-SRDLGSWnPSQLL 153
                  567777888888544433333333.....333334445666889**********************************998664.3333333334555 PP

  Hydrolase_4 131 gkllpklqv.......................snnlkadslsrdpevvaayeadplvhgkitvrlllelldamkrleeraakitlPllllhGeaDkvv 205
                   +++  ++                          n+ ++ +  ++++ + + +    ++k  vr++l +l   + l+ r+++i  P+  l+G++D + 
   EEA21882.1 154 LPFYDGWSAqketpgfviddawcgafagvggfGPNITPETVEFWTKNFKDTYKGDESRKK--VRMALICLLERDGLLLRVKDIACPVHWLQGTDDYIF 249
                  555555555666677777**********99997778888888888777755555444444..56666677788999********************** PP

  Hydrolase_4 206 dpeasrelyerlgsk.dktlklypglyHel 234
                    +  ++ + rl+s+ + +l++ pg+ H l
   EEA21882.1 250 GTKLPADHITRLTSAkETELTIVPGGAHYL 279
                  999998888888887699**********75 PP

>> Ndr  Ndr family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.9   0.0   1.6e-08   5.9e-05      84     132 ..      84     132 ..      22     142 .. 0.74

  Alignments for each domain:
  == domain 1  score: 21.9 bits;  conditional E-value: 1.6e-08
                 HHHTTHHHHHHHHT---EEEEEETHHHHHHHHHHHHSGGGEEEEEEES- CS
         Ndr  84 dladqllavldhfklksviglGvgaGAyilarfalkhperveglvLini 132
                 d a++ l+v+d++ ++++ +lGv  G +i++r al  p++++gl+L+ +
  EEA21882.1  84 DSAQTALQVIDKLGIQKAFALGVSQGGWIVTRMALLAPDKILGLMLLGT 132
                 55788899*************************************9865 PP

>> BAAT_C  BAAT / Acyl-CoA thioester hydrolase C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       1.3   4.6e+03     116     142 ..      18      44 ..      11      71 .. 0.61
   2 ?    1.9   0.0     0.051   1.8e+02       5      44 ..      82     121 ..      78     134 .. 0.73
   3 ?    9.5   0.0   0.00024      0.87     107     165 ..     227     281 ..     189     299 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1.3
                 SEEEEEEETT-SSS-HHHHHHHHHHHH CS
      BAAT_C 116 gpillvvgedDknwpSkesaekaserL 142
                 +++ +++g+ D + p+   +  +s+++
  EEA21882.1  18 ANYAFANGTHDPSKPTCVLITAMSMNI 44 
                 455555555555555544444444433 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.051
                 HHHHHHHHHHCSTTB--SSEEEEEETHHHHHHHHHHHHSS CS
      BAAT_C   5 YFeeainyllrhpkvkkdkigllGiSkGgelalllasflk 44 
                 Y++ a + l+   k+  +k   lG+S+Gg ++  +a   +
  EEA21882.1  82 YWDSAQTALQVIDKLGIQKAFALGVSQGGWIVTRMALLAP 121
                 55555556666666666666679************98776 PP

  == domain 3  score: 9.5 bits;  conditional E-value: 0.00024
                 CB--GGG--SEEEEEEETT-SSS-HHHHHHHHHHHHHCTT--.--EEEEETTB-S---S CS
      BAAT_C 107 alipvekakgpillvvgedDknwpSkesaekaserLkkagkkvevqlltYpkaGHliep 165
                  l++v ++ +p+  ++g+dD ++ +k  a + + rL+ a++  e++++  p++ H+++ 
  EEA21882.1 227 LLLRVKDIACPVHWLQGTDDYIFGTKLPA-DHITRLTSAKET-ELTIV--PGGAHYLNT 281
                 578999***********************.566799999888.89999..9999*9975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (301 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       323  (0.0180155); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2082.68
//
Query:       EEA21883.1  [L=359]
Description: NAD dependent epimerase/dehydratase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.5e-17   63.2   0.0    3.8e-17   62.6   0.0    1.3  1  Epimerase      NAD dependent epimerase/dehydratase family
    1.9e-08   34.1   0.0      3e-08   33.5   0.0    1.5  1  GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
    8.4e-06   25.1   0.0    1.2e-05   24.6   0.0    1.2  1  NAD_binding_4  Male sterility protein
    5.4e-05   22.3   0.0     0.0001   21.4   0.0    1.4  1  3Beta_HSD      3-beta hydroxysteroid dehydrogenase/isomerase 
  ------ inclusion threshold ------
       0.14   11.9   0.0       0.23   11.1   0.0    1.3  1  DUF1175        Protein of unknown function (DUF1175)


Domain annotation for each model (and alignments):
>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.6   0.0   1.1e-20   3.8e-17       1     232 [.      10     272 ..      10     280 .. 0.85

  Alignments for each domain:
  == domain 1  score: 62.6 bits;  conditional E-value: 1.1e-20
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC...........EEEE--TT-HHHHHHHHHHHT-SEEEE--S---HHHHHHSHHHHH CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl...........elveldltdrsalerlfkeeqpdavihlAavggvaassedpadfi 88 
                 +lVt ++Gfi s ++k +l++gy+v g +r  ++s++ ++++             +   d+t + a++++++  +++a++h    +  + s++dp+ +i
  EEA21883.1  10 VLVTAVNGFIASWTAKVFLDAGYNVRGTTRSAKSSHSMLEAEPfktyastgrfsIVQVPDITLPGAFDDAVR--GCHAIVHT--ASPMSLSFSDPEPVI 104
                 69999**************************9999999988889*******885555568888889999999..********..789999********* PP

                 HHHTHHHHHHHHHHH......HHTCTEEEEEEE.GGGGT...............SCSSSSBSTCSTTS--.--SSHHHHHHHHHHHHHHHHHHHH..T- CS
   Epimerase  89 eknlqgtlnlleaar......kagvkrllflsS.sevYG...............kdaeqpkeettltgpl.kpnspYaaaKlageklveayaaqy..gl 162
                 ++ +qg++ +le a+       + vk +++lsS ++v G                d+e+ ++e++  g+  ++ + Y a+K+a+e+ ++++++     +
  EEA21883.1 105 NTAVQGVRSVLESAHlsagagSSTVKSFVQLSSiATVIGkkpdddahyeftetdWDNES-ENEVARLGKQtPSMKIYKASKTAAERTMWDFQKNEkpTF 202
                 ***************88888888999*******9999**77776666666555423332.66777666667999*****************99984459 PP

                 EEEEEEESEEESTT...S-TTSTTSHHHHHHHHHHTTSSSEEE.ETTST-EEEEEEHHHHHHHHHHHHHHHTT- CS
   Epimerase 163 naiilrlfnlyGpr...ngegevsrvipalirkilegkqevtl.lgdgtalRdflyveDvaeaillvlehvdag 232
                  ++++++  + Gp      ++e+ +  ++++  + +g+ e+   lg ++     ++v+Dva+++l+++++ ++ 
  EEA21883.1 203 TMTAINPVFVWGPPllfPENPEDLNATAKVVWTVFSGQ-EIPPpLGGLNY---AVDVRDVARLMLFAVQEKEKA 272
                 99*************99999999999***********9.55540454444...699*************96553 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.5   0.0   8.3e-12     3e-08       1     144 [.      11     157 ..      11     290 .. 0.76

  Alignments for each domain:
  == domain 1  score: 33.5 bits;  conditional E-value: 8.3e-12
                    EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-T.THHHHHCTTT...TTGCCEEEEE-.-TT-HHHHHHHHHHHT-SEEEE--S---HHHHTTS CS
  GDP_Man_Dehyd   1 LiTGiaGfiGsylaelLlekgyevhgivrrsssfn.tgriehlakdpkeeleenlklhkg.DltDssslerllaevqpdevynLAAqshVdvsfek 94 
                    L+T ++Gfi s++a+ +l+ gy+v g++r ++s + + + e  +       +++++++++ D+t   + +++++ +  +++++ A  s  + sf++
     EEA21883.1  11 LVTAVNGFIASWTAKVFLDAGYNVRGTTRSAKSSHsMLEAEPFK---TYASTGRFSIVQVpDITLPGAFDDAVRGC--HAIVHTA--SPMSLSFSD 99 
                    8**************************99876644033333333...3445789**99977*************98..8****88..67889**** PP

                    HHHHHHHHTHHHHHHHHHHHHC...T..TTSEEEEEEE.GGGG-S-S....SSSB-TT CS
  GDP_Man_Dehyd  95 PeytaevnvlGtlrLLeairal...glekkvrfyqaSt.sEvYGkvq....evpqtEt 144
                    Pe ++++ v G+  +Le +      g ++ + f+q S+ ++v Gk      +  +tEt
     EEA21883.1 100 PEPVINTAVQGVRSVLESAHLSagaGSSTVKSFVQLSSiATVIGKKPdddaHYEFTET 157
                    ******************9866554666778999999867788887522212334554 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.6   0.0   3.5e-09   1.2e-05      81     197 ..      76     200 ..      69     258 .. 0.74

  Alignments for each domain:
  == domain 1  score: 24.6 bits;  conditional E-value: 3.5e-09
                    HHHHHHH--EEEE--SS-S.ST.TSSEEHHHHHHHHHHHHHHHT.....SSS--.-EEEEEE..GGGTTS-TTT--SSS-H......HHH--EEEE CS
  NAD_binding_4  81 lqelaeevdviihsaAtvnfde.pykellrvNveGtrevlelak.....klkklkvllhvST..ayvngeregeveekvyeegekeekldederak 168
                    +++ ++ +++i+h a  +++   + + ++++ v+G+r vle a+     + +  k++++ S+   ++ ++  +  + +++e+ +++e ++e +r  
     EEA21883.1  76 FDDAVRGCHAIVHTASPMSLSFsDPEPVINTAVQGVRSVLESAHlsagaGSSTVKSFVQLSSiaTVIGKKPDDDAHYEFTETDWDNESENEVARLG 171
                    666778899********999872556699**************987776445558********444555555566666666666777777776655 PP

                    TTTCCC.HHHHHHHHHHHHHHHHHHHH--- CS
  NAD_binding_4 169 lkglpn.tYeqsKalaEklvrearrrsglp 197
                    ++  +   Y+ sK +aE+ + + +++ + p
     EEA21883.1 172 KQTPSMkIYKASKTAAERTMWDFQKN-EKP 200
                    55544449***********9998866.444 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0   2.9e-08    0.0001       3     184 ..      13     215 ..      11     221 .. 0.62

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 2.9e-08
   3Beta_HSD   3 tGgaGFlGralvkeLvrlee..lkevrvlDlrespelleelskvnvkk....viegDvtdkdkleealegvdvvihlaslvdvagkltedeimkvnvkG 95 
                 t   GF+ +   k +++++     + r++   +s    e +++   +     v   D+t     ++a++g ++++h+as + +      + + +  v+G
  EEA21883.1  13 TAVNGFIASWTAKVFLDAGYnvRGTTRSAKSSHSMLEAEPFKTYASTGrfsiVQVPDITLPGAFDDAVRGCHAIVHTASPMSLSF-SDPEPVINTAVQG 110
                 55566666666666666664212233333333333222333332222244445556*********************88777665.66777999***** PP

   3Beta_HSD  96 Trnvleacv......kagvrvlvYtSsaevvgpnslge....eilngdEeleyesl.........hqdaypesKalaEklvlkaNgrtlkngg.rlyTc 174
                  r+vle++       ++ v+ +v  Ss+  v + +  +    e+++ d + e e+           +++y+ sK  aE+ +         n + ++   
  EEA21883.1 111 VRSVLESAHlsagagSSTVKSFVQLSSIATVIGKKPDDdahyEFTETDWDNESENEvarlgkqtpSMKIYKASKTAAERTMWDFQK----NEKpTFTMT 205
                 *****9976333333567********987555434333111134433322222221223344455788999999999999876655....445489999 PP

   3Beta_HSD 175 aLRpagiyGe 184
                 a+ p+ ++G+
  EEA21883.1 206 AINPVFVWGP 215
                 9999999998 PP

>> DUF1175  Protein of unknown function (DUF1175)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   6.5e-05      0.23      52      97 ..     254     300 ..     246     307 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 6.5e-05
     DUF1175  52 eerDCaglvryavrEalkkhdarwleksglsg.PvvedvekylyPel 97 
                   rD a l+ +av+E  k+ d+r+ ++sg++   +v+dv ++ yP+ 
  EEA21883.1 254 DVRDVARLMLFAVQEKEKASDQRFITASGVRShQAVADVLREAYPDR 300
                 679***************************99899**********85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (359 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       386  (0.0215294); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.51u 0.30s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 2380.41
//
Query:       EEA21884.1  [L=315]
Description: possible apospory-associated protein c [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.7e-39  135.9   0.1      2e-39  135.7   0.1    1.0  1  Aldose_epim  Aldose 1-epimerase


Domain annotation for each model (and alignments):
>> Aldose_epim  Aldose 1-epimerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  135.7   0.1   1.1e-43     2e-39       9     300 ..      35     311 ..      28     312 .. 0.91

  Alignments for each domain:
  == domain 1  score: 135.7 bits;  conditional E-value: 1.1e-43
                  TEEEEEECTCTTEEEEEEETT.STEESB-B-STHHHHHHSCCSSCEECSS-SEEETTEEEETTEEEECCCCBT.......TTCEETBSGGGSB-EEEE CS
  Aldose_epim   9 aglsakislyGAtllslkvpdkeqrevllgsddaeeylkdsyfgatlgrvanRianGeFeldGkpyqlpqnee.......gknplHGgargreWevee 99 
                   g s+++ l+GAt++s+k     ++e l+ s++          ++++g++a+R   G     G+p+ +p++++       + +p+HG+ar+++We+  
   EEA21884.1  35 SGESVTVHLFGATVISWKLAT--GAEQLFVSSK----------AILDGSKAIR---G-----GIPVVFPVFGPpppnhatSSLPQHGFARSSNWEYLG 112
                  6789*****************..88********..........6*********...8.....************************************ PP

                  EEE........TTEEEEEEEEEEETC.HC....STSEEEEEEEEEEETTEEEEEEEEEEESS.S-EEEEEEEEEEEETSSCTCTGGEEEEEEEEEEEE CS
  Aldose_epim 100 vke........ddgvtvslvlkpdge.eg....ypgdlevrvtytLnednelkieyeatndg.kptpfnltnHtYFnlsgesidshelqieadeylev 183
                  +++        d++v +++ l+ +   e+    +p+++ + +++tL+ d  l+  ++++n+g +++ f + +H YF ++    d +++ +++++   +
   EEA21884.1 113 KSSseslgnkaDTTVKLDFGLSSSMIsEEfrkaWPYEFGLVYSVTLSPDR-LETSLQVQNKGsESFDFHVLLHNYFKVP----DVSKIAVTNLQNKIY 205
                  *999*****885555555555333222336789***************99.999999999999****************....*********999999 PP

                  CTTSGEEEEEEECTTCCCCCCSSEEHCSSETEEEEEEEESSCSEEEEEETTTTEEEEEEEETTSSEEEEEECTTTT.SEECCEEESSECTCETCCCEC CS
  Aldose_epim 184 deeliptgelkdvkgtpfdfrqpkaigedlkglDhayllksklkaviidpdkksgiklevsttepalvvytgnflk.kylsreglaletqmlpdepnh 280
                   +         +v+++  +++   +i+ ++ ++D++yl    +   + ++++++ +   ++++ +++ v++++ ++ k +s++g+++++ m+++ep+ 
   EEA21884.1 206 ID---------KVDDKKEKTETTNEITITG-ETDRVYLDVD-PSDPVSIVENGQPLFTINRKELNTVTVWNPWVENaKKMSDFGDEEYKGMVCVEPGA 292
                  99.........8888888888888888888.99*******9.888889999*********************************************** PP

                  HHHT-EEEHTTTEEEEEEEE CS
  Aldose_epim 281 pefpsivlkpGesysaetsy 300
                  +++   vl+ G  ++ ++ +
   EEA21884.1 293 VKSW-SVLEGGDAWEGTQTI 311
                  **99.9********999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (315 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       559  (0.0311785); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2231.65
//
Query:       EEA21885.1  [L=315]
Description: possible apospory-associated protein c [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.7e-39  135.9   0.1      2e-39  135.7   0.1    1.0  1  Aldose_epim  Aldose 1-epimerase


Domain annotation for each model (and alignments):
>> Aldose_epim  Aldose 1-epimerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  135.7   0.1   1.1e-43     2e-39       9     300 ..      35     311 ..      28     312 .. 0.91

  Alignments for each domain:
  == domain 1  score: 135.7 bits;  conditional E-value: 1.1e-43
                  TEEEEEECTCTTEEEEEEETT.STEESB-B-STHHHHHHSCCSSCEECSS-SEEETTEEEETTEEEECCCCBT.......TTCEETBSGGGSB-EEEE CS
  Aldose_epim   9 aglsakislyGAtllslkvpdkeqrevllgsddaeeylkdsyfgatlgrvanRianGeFeldGkpyqlpqnee.......gknplHGgargreWevee 99 
                   g s+++ l+GAt++s+k     ++e l+ s++          ++++g++a+R   G     G+p+ +p++++       + +p+HG+ar+++We+  
   EEA21885.1  35 SGESVTVHLFGATVISWKLAT--GAEQLFVSSK----------AILDGSKAIR---G-----GIPVVFPVFGPpppnhatSSLPQHGFARSSNWEYLG 112
                  6789*****************..88********..........6*********...8.....************************************ PP

                  EEE........TTEEEEEEEEEEETC.HC....STSEEEEEEEEEEETTEEEEEEEEEEESS.S-EEEEEEEEEEEETSSCTCTGGEEEEEEEEEEEE CS
  Aldose_epim 100 vke........ddgvtvslvlkpdge.eg....ypgdlevrvtytLnednelkieyeatndg.kptpfnltnHtYFnlsgesidshelqieadeylev 183
                  +++        d++v +++ l+ +   e+    +p+++ + +++tL+ d  l+  ++++n+g +++ f + +H YF ++    d +++ +++++   +
   EEA21885.1 113 KSSseslgnkaDTTVKLDFGLSSSMIsEEfrkaWPYEFGLVYSVTLSPDR-LETSLQVQNKGsESFDFHVLLHNYFKVP----DVSKIAVTNLQNKIY 205
                  *999*****885555555555333222336789***************99.999999999999****************....*********999999 PP

                  CTTSGEEEEEEECTTCCCCCCSSEEHCSSETEEEEEEEESSCSEEEEEETTTTEEEEEEEETTSSEEEEEECTTTT.SEECCEEESSECTCETCCCEC CS
  Aldose_epim 184 deeliptgelkdvkgtpfdfrqpkaigedlkglDhayllksklkaviidpdkksgiklevsttepalvvytgnflk.kylsreglaletqmlpdepnh 280
                   +         +v+++  +++   +i+ ++ ++D++yl    +   + ++++++ +   ++++ +++ v++++ ++ k +s++g+++++ m+++ep+ 
   EEA21885.1 206 ID---------KVDDKKEKTETTNEITITG-ETDRVYLDVD-PSDPVSIVENGQPLFTINRKELNTVTVWNPWVENaKKMSDFGDEEYKGMVCVEPGA 292
                  99.........8888888888888888888.99*******9.888889999*********************************************** PP

                  HHHT-EEEHTTTEEEEEEEE CS
  Aldose_epim 281 pefpsivlkpGesysaetsy 300
                  +++   vl+ G  ++ ++ +
   EEA21885.1 293 VKSW-SVLEGGDAWEGTQTI 311
                  **99.9********999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (315 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       559  (0.0311785); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 2072.11
//
Query:       EEA21886.1  [L=613]
Description: MFS multidrug transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.6e-27   94.6  18.9    5.6e-27   94.6  18.9    1.5  1  MFS_1     Major Facilitator Superfamily
    0.00086   18.3   3.0     0.0016   17.4   3.0    1.4  1  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.6  18.9   6.3e-31   5.6e-27      33     353 .]     135     550 ..      96     550 .. 0.82

  Alignments for each domain:
  == domain 1  score: 94.6 bits;  conditional E-value: 6.3e-31
       MFS_1  33 eigllltlyalgaavaslplGrlsd..rfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsa 128
                 ++g+  + ++++++++s+ +Gr +d  r+Gr+rvll+gl++++++++ + f s ++ + +++r+l Gl+ + +  +   +   ++ k+ ++ra+ ll +
  EEA21886.1 135 QAGIFQGSFTAAQFLTSVWWGRAADshRVGRKRVLLVGLFGTLISCVGFGF-SRSFtAAIIFRILGGLMNSNVGVMRTMISEIIVEKKFQSRAFLLLPM 232
                 58888999***************997788****************666669.88888************877777776666667777************ PP

       MFS_1 129 gfslGailgpllggllasslg.....................Wravfyilaivsllafv.lfllllpeepperkrkspkeee................. 188
                 +f++G+i+gp lgg+la+ +                       ++++ +  +vs+++++  ++  ++  + +++  ++++++                 
  EEA21886.1 233 CFNVGVIIGPSLGGFLAEPVTsfpglfgpgsllggkdgiwwmRHWPYALPNLVSAVFIIsAWAGIFFGLEETHEVLRHRPDWgramgstiakrfrrnqg 331
                 *****************66667*****************988577788888888888888777777777777777777777777*************** PP

       MFS_1 189 .............................kgtgpaplvp...awkallkdpvlwillialllf...ffgfsglltllpl............ylqevlgl 240
                                                ++p p++     wk+ll+++v++ +l+++ll+   ++++++++++lp+             ++  lgl
  EEA21886.1 332 yryrrldddersvfledddeavppnattmRHPEPLPIAHkrsTWKQLLTRNVVLTVLTHSLLAmhtSAFNAMTFVFLPTprapedsrrgffHFNGGLGL 430
                 ******9999999999998888888887755666666668889*********98566666666343334555999999999999999887635999999 PP

       MFS_1 241 sglllaglllallalvgailallagrls.drlgrrrrlllallllllaalglallavt....ssavllllvlvl.iGf.glgfvfpsllalasdla.pp 331
                 +   ++g++ ++++l+g++l+l++   +  rlg  r l  +l+l  la+ ++ +l ++    +  ++  +++v+ + +    fv p+++ l+++++  p
  EEA21886.1 431 T-TQQVGIATSVIGLIGLPLQLFVYPRVqFRLGTLRSLRSFLPLSPLAYTLMPFLVLIprgaQYLIWPSFSFVVaLQVlSRTFVLPAAIILVNNSVsDP 528
                 9.8*****************77776666699999777777777777777777777777543344444444333357777999999***99999999888 PP

       MFS_1 332 eeagtasglfntagslggalgp 353
                 +  gt+ g++++++s ++ lgp
  EEA21886.1 529 SVLGTIHGVAQSISSGSRTLGP 550
                 *******************998 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   3.0   1.8e-07    0.0016      44     116 ..     132     203 ..      93     250 .. 0.78

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 1.8e-07
                 ...HHHHHHHTHHHHHHHHHHHHHHHHH..HTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHH CS
    Sugar_tr  44 ssvlsglivsiflvGaiiGslfagllgd..rfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigv 116
                  s + g++ ++f + ++++s+  g ++d  r+GRk +ll++ + ++i+ v  +++    s+ + i+ R+l G+  
  EEA21886.1 132 ISRQAGIFQGSFTAAQFLTSVWWGRAADshRVGRKRVLLVGLFGTLISCVGFGFSR---SFTAAIIFRILGGLMN 203
                 56789********************9864489************************...*************963 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (613 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       479  (0.0267165); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.27s 00:00:00.88 Elapsed: 00:00:00.44
# Mc/sec: 4167.00
//
Query:       EEA21887.1  [L=138]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.01   15.6   0.2      0.029   14.2   0.0    1.9  2  UBA_4     UBA-like domain


Domain annotation for each model (and alignments):
>> UBA_4  UBA-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.2      0.27   4.8e+03      12      26 ..      19      33 ..      18      35 .. 0.72
   2 ?   14.2   0.0   1.6e-06     0.029      15      37 ..     110     132 ..     103     135 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.27
       UBA_4 12 GadeekArqlLeann 26
                +a++ kA   L++ n
  EEA21887.1 19 NAEDRKAAAALNSLN 33
                678888888887765 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 1.6e-06
       UBA_4  15 eekArqlLeannWdLerAislyF 37 
                  +kA++lL+++++d   Ai +++
  EEA21887.1 110 KNKATELLRSHDGDAKEAIRAFL 132
                 589*****************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (138 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       646  (0.036031); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.37u 0.25s 00:00:00.62 Elapsed: 00:00:00.40
# Mc/sec: 1036.13
//
Query:       EEA21888.1  [L=477]
Description: phospho-2-dehydro-3-deoxyheptonate aldolase, class II [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   7.1e-202  670.7   0.0     8e-202  670.5   0.0    1.0  1  DAHP_synth_2  Class-II DAHP synthetase family


Domain annotation for each model (and alignments):
>> DAHP_synth_2  Class-II DAHP synthetase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  670.5   0.0  4.4e-206    8e-202       1     437 []       4     463 ..       4     463 .. 0.99

  Alignments for each domain:
  == domain 1  score: 670.5 bits;  conditional E-value: 4.4e-206
  DAHP_synth_2   1 wspsswrskpaaqqpeyedeealekvlkklkklpplvtaeeieklkeqLaevaegkaflLqgGdCaEsfeectaekieeklkvllqmslvltlgasl 97 
                   wsp+sw skp++q+++y+d ea++++l kl++lpplvt++ei +lk++L+++a gkaf+LqgGdCaE f++c++++ie+k+k+llqmslvl++ga++
    EEA21888.1   4 WSPTSWTSKPIKQDVTYDDPEAVDAALVKLQRLPPLVTPHEIVHLKNSLRNAALGKAFVLQGGDCAELFDYCNQDTIEAKVKLLLQMSLVLVWGANK 100
                   99*********************************************************************************************** PP

  DAHP_synth_2  98 pvvkigRiAGqyaKPRSsetetvdgkelpsyrGdivnglelteeeRepdPerllkaYfhsaatlnlvrallssgladlekveewnlefvksselkek 194
                   pvv+i+RiAGq+aKPRSs++et++g+++ps+rGd++ng+++t+e+R+pdP+rl++aYfhsaatln++ra+l+sg+adl+++ +w l+++  +++k+k
    EEA21888.1 101 PVVRIARIAGQFAKPRSSPNETINGVTMPSFRGDNINGFDATPESRKPDPSRLVSAYFHSAATLNYLRAALASGIADLHSPLDWGLGHIIAPSIKQK 197
                   ************************************************************************************************* PP

  DAHP_synth_2 195 yeelaeeleealefmkaigvdeeeeeeleevdlytsHeaLlleyeealtr.........................kdsetklydtsahflWiGdRTr 266
                   ye++++ +++al+fm+++gvd+  ++++ ++d+ytsHe+L leye+ +tr                         +  ++++ydtsahflWiGdRTr
    EEA21888.1 198 YEKITNAVTDALRFMHTVGVDQ--DRRVATADIYTSHEGLSLEYEQCFTRllrhppeafpsptesrderlrrgssAAISKGYYDTSAHFLWIGDRTR 292
                   ********************87..56799******************************************9986556677**************** PP

  DAHP_synth_2 267 qldgahveflrgieNpigvKvgpslkpeelvelldilnPekepGrltlitRlgadkveelLpklieavkksgakvvwvcDpmHGNtltsssglKtRe 363
                   q+ gahvef+rg++Npig+K+gp+++++elvell+++nP+ke G++tli+R+gadk++++Lp++i+av++sg+  vw+cDpmHGNt++++sg+KtR+
    EEA21888.1 293 QVTGAHVEFFRGLSNPIGIKIGPTMTTDELVELLNTVNPTKEVGKVTLISRYGADKIAQYLPAHIAAVQASGHLPVWQCDPMHGNTQSTPSGVKTRH 389
                   ************************************************************************************************* PP

  DAHP_synth_2 364 fedilkEvksfleihkeegsvlgGvhlEltgedVtEclggseelseedlserYetlcDPRLnaeqslelaflia 437
                   f++il+E+k++leih++ gs+lgG+hlEltge+VtEc+gg+  l+ee lserYet+cDPRLn++q+lelafl+a
    EEA21888.1 390 FTNILSELKQALEIHRAAGSYLGGMHLELTGEAVTECVGGAGGLTEEGLSERYETFCDPRLNEKQALELAFLVA 463
                   ************************************************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (477 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       335  (0.0186848); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 3359.33
//
Query:       EEA21889.1  [L=486]
Description: GPI anchored cell wall protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.9e-52  176.1   3.3    9.7e-52  175.1   3.3    1.5  1  But2      Ubiquitin 3 binding protein But2 C-terminal domain


Domain annotation for each model (and alignments):
>> But2  Ubiquitin 3 binding protein But2 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  175.1   3.3   5.4e-56   9.7e-52       1     142 []     336     476 ..     336     476 .. 0.99

  Alignments for each domain:
  == domain 1  score: 175.1 bits;  conditional E-value: 5.4e-56
        But2   1 efPhlIvpvssssPdkafgtsyngtvsstdvstifnFdipasaagktCslvflfptqsqletssytlsGsgkfkfsklaapatesttynnkPavkeelg 99 
                 efPhlI+p++sssP+ka gts+ngt++st vs+ifnFd   s+a+k+Cslvflfptq++letss+++sG+g ++f +l+apa++st+++n+P+vk ++g
  EEA21889.1 336 EFPHLIIPIDSSSPNKAAGTSFNGTITST-VSSIFNFDFLPSSANKQCSLVFLFPTQDKLETSSFSFSGDGAIRFLELQAPASSSTSFSNAPQVKVDFG 433
                 7****************************.**********9999******************************************************* PP

        But2 100 kttlspGnaytiasfpCpagqavsyevssagdtsLeffqdynp 142
                  t++spG+ +tia+f+Cpagq+v++e+++ag+tsL+ff+d+np
  EEA21889.1 434 VTNVSPGHVFTIATFACPAGQTVAFELKNAGSTSLDFFEDFNP 476
                 ******************************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (486 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       329  (0.0183502); expected 358.6 (0.02)
Passed bias filter:                      184  (0.0102627); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 3298.07
//
Query:       EEA21890.1  [L=354]
Description: calcium homeostasis protein Regucalcin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      8e-68  228.7   0.1      1e-67  228.3   0.1    1.1  1  SGL           SMP-30/Gluconolactonase/LRE-like region
  ------ inclusion threshold ------
      0.026   14.1   0.1      0.036   13.7   0.1    1.2  1  Phosphodiest  Type I phosphodiesterase / nucleotide pyrophosp
      0.034   14.3   0.0      0.069   13.3   0.0    1.5  1  Arylesterase  Arylesterase
      0.056   13.4   0.0      0.097   12.6   0.0    1.4  1  Phytase-like  Esterase-like activity of phytase
       0.29   11.5   1.5         36    5.1   0.1    2.8  2  Reg_prop      Two component regulator propeller


Domain annotation for each model (and alignments):
>> SGL  SMP-30/Gluconolactonase/LRE-like region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  228.3   0.1   2.9e-71     1e-67       3     237 ..      68     312 ..      66     318 .. 0.92

  Alignments for each domain:
  == domain 1  score: 228.3 bits;  conditional E-value: 2.9e-71
         SGL   3 EGpvwdeeegaLlwvDilgqrihrldpatgketv..ldtpesvGaiap.rkd....grlvvasksglalldlasgeletlade..eedekpllrfNDgv 92 
                 EGp + +e+++L +vD   ++++ ld+a+g++++  l+t++++G++a+  +d     ++vva+k+g+a +d++sg+l+++ +    e++  ++rfNDg+
  EEA21890.1  68 EGPFYTAERNELRFVDLDYEKVYFLDLAKGPSSMrvLHTESPIGVTADmIDDtgnnTQIVVAAKHGFATMDYQSGALTYIHRThiSEEQAYRMRFNDGA 166
                 9*****************************99877799999*******7333556799**********************99866567779******** PP

         SGL  93 vdpdGrlwfGtmgdee.akgeevgalyrldpdgklervlddltipNGlawspdgktlYlaDsltrkiwaydvdaeggklsnrrvfadlkkgegepDGla 190
                 vd +Gr+w+G+  d++ ++g++ g+lyrld d +l++++ ++t pNG++w+++++t+Y++Ds+++ki+ay++da +g +sn+r f++l+ + gepDG+a
  EEA21890.1 167 VDNQGRFWAGSSIDHKyVQGKHAGTLYRLDSDMSLHEMVHQITTPNGMGWNSADDTMYITDSPHGKIYAYEFDARTGSISNKRDFLTLEANYGEPDGFA 265
                 **********9766651566666**************************************************************************** PP

         SGL 191 vDaeGnvwvAvwgggkvvrfdpdGklieeiklpakrvtscaFgGpdl 237
                 +D eGn+wvAvw+g++++r++p+G++++ei +p++ vt++ F G++l
  EEA21890.1 266 MDVEGNLWVAVWRGSRIIRVNPKGEITGEILFPTRFVTCPEFVGSEL 312
                 *********************************99*******99984 PP

>> Phosphodiest  Type I phosphodiesterase / nucleotide pyrophosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.1     1e-05     0.036     213     254 ..     115     164 ..     107     244 .. 0.61

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1e-05
                   HHHHHTTGTTTEEEEEEES---EEEH.TTS.EEEGGGTSTGGH............G CS
  Phosphodiest 213 ealderglsaetniilvSDHGmadvs.ddk.vielndlleekg............l 254
                   + +d++   ++t+i++++ HG+a+++ +++ ++++++                  +
    EEA21890.1 115 DMIDDT--GNNTQIVVAAKHGFATMDyQSGaLTYIHRT----HiseeqayrmrfnD 164
                   566777..689**************8553323333332....22222444333331 PP

>> Arylesterase  Arylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   1.9e-05     0.069      45      83 ..     200     238 ..     172     241 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.9e-05
  Arylesterase  45 evkvvasglssanGInidadkkyiyvadilresihvmkk 83 
                    +++++++++++nG++ ++ +  +y++d+ + +i++++ 
    EEA21890.1 200 SLHEMVHQITTPNGMGWNSADDTMYITDSPHGKIYAYEF 238
                   46788999*****************************86 PP

>> Phytase-like  Esterase-like activity of phytase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   2.7e-05     0.097      21     111 ..     225     302 ..     166     319 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 2.7e-05
  Phytase-like  21 lsDrgsknsarfytlkldldadklgkveitevtplkdpdgapfpkkglDpEgiavapdgtfwvssEggpfilefdadGkllrelplpaell 111
                   ++D+ +    ++y +++d    ++g+++ ++    + +       +   p g+a++ +g++wv+  +g +i++++++G++++e+  p ++ 
    EEA21890.1 225 ITDSPH---GKIYAYEFDA---RTGSISNKRDFLTLEA-------NYGEPDGFAMDVEGNLWVAVWRGSRIIRVNPKGEITGEILFPTRFV 302
                   444444...3333333333...2244443322222222.......223677*********************************9999995 PP

>> Reg_prop  Two component regulator propeller
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.1      0.01        36      12      22 ..     167     177 ..     164     178 .. 0.89
   2 ?    4.6   0.2     0.015        52      11      22 ..     265     276 ..     262     278 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.01
                 E-TTSCEEEEE CS
    Reg_prop  12 eDsdGrlWvGt 22 
                  D++Gr W G+
  EEA21890.1 167 VDNQGRFWAGS 177
                 69*******98 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.015
                 EE-TTSCEEEEE CS
    Reg_prop  11 leDsdGrlWvGt 22 
                 + D +G+lWv+ 
  EEA21890.1 265 AMDVEGNLWVAV 276
                 67889*****85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (354 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       308  (0.0171789); expected 358.6 (0.02)
Passed bias filter:                      276  (0.0153941); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 2293.43
//
Query:       EEA21891.1  [L=579]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
     0.0028   17.7   9.5     0.0028   17.7   9.5    1.9  2  bZIP_2       Basic region leucine zipper
  ------ inclusion threshold ------
       0.03   14.0   6.6      0.054   13.2   6.6    1.4  1  BSP_II       Bone sialoprotein II (BSP-II)
        1.1    8.8  13.5        2.5    7.7  13.5    1.7  1  Spt20        Spt20 family


Domain annotation for each model (and alignments):
>> bZIP_2  Basic region leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -6.9   5.4         3   1.8e+04      31      31 ..      25      25 ..      13      48 .. 0.51
   2 !   17.7   9.5   4.8e-07    0.0028       5      47 ..     403     444 ..     399     449 .. 0.89

  Alignments for each domain:
  == domain 1  score: -6.9 bits;  conditional E-value: 3
                H CS
      bZIP_2 31 e 31
                +
  EEA21891.1 25 Q 25
                1 PP

  == domain 2  score: 17.7 bits;  conditional E-value: 4.8e-07
                 XXXXXXXXXXXXXX-HHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_2   5 yrerRrkNreAarrsRekkkakeeeleervkeLeeeNaqLrqk 47 
                 + e+R+ N  A+rr+R +kk +e+ le+r+++L+e+ ++L ++
  EEA21891.1 403 QAEKRKANSDASRRFRNRKK-NEAALEQRINQLNEQLQFLTEE 444
                 679**************988.6789**************9765 PP

>> BSP_II  Bone sialoprotein II (BSP-II)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   6.6   9.1e-06     0.054      48     141 ..      17     114 ..       5     122 .. 0.63

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 9.1e-06
      BSP_II  48 sdsseEngdGdsseEeeeeeetsneeenn.eesnenedeeseaenttlsattp......gygeektqgkgsiGlaaiklpkkagdieekatkeeesdee 139
                  +  + +++G   eE+ee+e+ +n++en  +++ +ne  +sea  t  s   p         e++t+++  iG+++i +p   g+ +    k+  +d++
  EEA21891.1  17 QQQQQQQQQGGH-EEQEEQEQVANNNENRiQQAASNESHQSEATGTKRSYPWPepavlqPRLESSTHARSIIGVQSILNPTEGGNSQVD--KRLAQDSN 112
                 444455556644.455555555444444415589999999***99999987777777766778999**************986654433..22222222 PP

      BSP_II 140 ee 141
                 + 
  EEA21891.1 113 NS 114
                 22 PP

>> Spt20  Spt20 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7  13.5   0.00042       2.5     118     160 ..      15      61 ..       2     121 .. 0.59

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00042
       Spt20 118 qqqqqqqqqqqq....qqeqqqqqnekdsttteekekksksknnssk 160
                 +qqqqqqqqqq     q+eq+q++n+++++ ++  +++s +++++++
  EEA21891.1  15 KQQQQQQQQQQGgheeQEEQEQVANNNENRIQQAASNESHQSEATGT 61 
                 22222222222222223333333333333333333333333322222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (579 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2070  (0.115455); expected 358.6 (0.02)
Passed bias filter:                      822  (0.0458475); expected 358.6 (0.02)
Passed Vit filter:                       133  (0.00741815); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.89u 0.32s 00:00:01.21 Elapsed: 00:00:00.51
# Mc/sec: 3429.76
//
Query:       EEA21892.1  [L=510]
Description: acid phosphatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.3e-59  201.7   0.0    2.7e-59  201.5   0.0    1.0  1  His_Phos_2  Histidine phosphatase superfamily (branch 2)


Domain annotation for each model (and alignments):
>> His_Phos_2  Histidine phosphatase superfamily (branch 2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  201.5   0.0   1.5e-63   2.7e-59       2     383 .]     107     466 ..     106     466 .. 0.89

  Alignments for each domain:
  == domain 1  score: 201.5 bits;  conditional E-value: 1.5e-63
                 EEEEEEEEE--SBB-SHHHHHHHHHHHHHHHH.........HHCHHTGCCGGGGT.........--SSSTTS.B-HHHHHHHHHHHHHHHHHCHTCCHT CS
  His_Phos_2   2 LksvvvviRHGdRtPkqkvkksvtspiflsllkkhkeKlkqlktalekkghfpgtyrkveveklqlilkwggelthaGrkqaeelGrqfrqrYplgLlr 100
                 +++v+v++RHG+R+P+  + +++ s+  +++           +t++++    +         +  ++l+++  lt++G+++++++G+ f+ rY  +L+r
  EEA21892.1 107 ITFVQVLSRHGARYPTAHKSAKYASLVNKIQQ---------TATEYKTHVYAL-------LKEYRYELGADN-LTSFGEQEMFDMGTTFYDRYG-QLAR 187
                 789*****************999999997666.........677777664444.......24459*******.*********************.**** PP

                 TSS--TTEEEEEESSHHHHHHHHHHHHHHCHCCC---S-TTSTTGGG-TTTTCCCEEEHHHHCCCCHHCTTSHHTCHHHCHHHTGGHCHHHHCHCCCCC CS
  His_Phos_2 101 lhltykdlkirassegRviaSAaafakGllglegeltdllskdkdllddsnaakdlldeakkklkelltegaeacpafewpikvakrvdelvkylkedm 199
                 +     ++++ras+++RviaS++ f kG+ +++       ++d+d ++ +   + +++e       ++t +  +c++f +       v++  +++  ++
  EEA21892.1 188 N----TVPFVRASGSDRVIASGELFSKGFNKAKT-----SDQDSDKSQRNSSVNLVIPE---GHVWNNTLDTGTCETFSN----GSPVQKIRQEFLHVF 270
                 *....89***********************9999.....66666666666666777777...333344456679****99....777777788899999 PP

                 HHHHHHHCHHHCTTEEEE-HHHHHHHHHHHHHHHH...HHCT-TTGGGCTH..HCHHHHHHHHHHHHHHHC........TTTCCCCHHHHHHHHHHHHH CS
  His_Phos_2 200 deniakrleqlcpgesnllakerwdklercfyekn...kfdiskicdlydemkydalhnrylkdleelyklakvipqEygigpeeklkiGllllnpllk 295
                  ++i +rl +++p+  +l+ +++  ++++c +e+    + + s+ c+l++    ++  ++y++ le++y          g g++++ ++G++++n+l+ 
  EEA21892.1 271 GPSILQRLVSNMPSV-SLELDDIPLLMDLCPFETVnspNGTSSPLCNLFSP--PEWKSYDYYNTLEKYYAF--------GAGNSLGSTRGVGYVNELIS 358
                 999999999999998.*******************999999**********..******************........******************** PP

                 HHCTSSSEECCS..........CCCECS-SEEEEEE-HHHHHHHHHHCTTTTTBTTB.SSS......TTT..HCCCS-CT-EEEEEEEEE.....TCTT CS
  His_Phos_2 296 kilndlqrtree..........atperhvrlrlyfthdshiysllnaLglpeelagedslaa.....ldrlsaspelpymsqivfelyed.....ssek 374
                 +++++l  +  +          at++ + +l+++f+hd+ ++s++ a+gl++++++++ +++     +++++as+++p++++ +fe++++     +   
  EEA21892.1 359 RMTKSLPVNDHTsvnhtldsdpATFPLDTALYADFSHDNAMMSIFDAFGLYNSTNPLSAKRVqstneTQGFAASWIVPFAARAYFEVMRCsvddhEG-- 455
                 ***9987666566********************************************99999***************************98875333.. PP

                 T..EEEEEEEC CS
  His_Phos_2 375 k..fyvrllls 383
                 k    vr+l++
  EEA21892.1 456 KeeDLVRVLIN 466
                 2359***9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (510 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       625  (0.0348597); expected 358.6 (0.02)
Passed bias filter:                      571  (0.0318478); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.49
# Mc/sec: 3160.45
//
Query:       EEA21893.1  [L=882]
Description: GPI-anchored cell surface glycoprotein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
     0.0014   18.6  13.8     0.0014   18.6  13.8    2.7  3  Trypan_PARP  Procyclic acidic repetitive protein (PARP)


Domain annotation for each model (and alignments):
>> Trypan_PARP  Procyclic acidic repetitive protein (PARP)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -5.1   1.3         1   1.8e+04      45      52 ..     341     348 ..     330     379 .. 0.41
   2 !   18.6  13.8   7.8e-08    0.0014      54     114 ..     531     557 ..     498     587 .. 0.56
   3 ?   -3.1   1.0       0.4   7.3e+03      54      79 ..     822     847 ..     788     868 .. 0.52

  Alignments for each domain:
  == domain 1  score: -5.1 bits;  conditional E-value: 1
  Trypan_PARP  45 kgtkvsdd 52 
                  k tk +  
   EEA21893.1 341 KSTKEQGS 348
                  22222221 PP

  == domain 2  score: 18.6 bits;  conditional E-value: 7.8e-08
  Trypan_PARP  54 tngtdpepepepepepepepepepepetepeeepepepepepepepepepepepepepgaa 114
                  ++ +   pepepepepepepepepe                                    
   EEA21893.1 531 VEEAPEAPEPEPEPEPEPEPEPEPEA----------------------------------P 557
                  22222223333333333333333332..................................2 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 0.4
  Trypan_PARP  54 tngtdpepepepepepepepepepep 79 
                  + gt ++ +++ +  p   p + p +
   EEA21893.1 822 AVGTATNNNNKTGGTPASTPSTAPPK 847
                  33444444444444444444444333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (882 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       893  (0.0498076); expected 358.6 (0.02)
Passed bias filter:                      267  (0.0148921); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.74u 0.27s 00:00:01.01 Elapsed: 00:00:00.45
# Mc/sec: 5871.99
//
Query:       EEA21894.1  [L=284]
Description: oligosaccharyltransferase subunit ribophorin II, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.8e-27   96.2   0.0    2.1e-27   96.0   0.0    1.0  1  Ribophorin_II  Oligosaccharyltransferase subunit Ribophorin I
  ------ inclusion threshold ------
       0.68   10.0   6.1       0.27   11.3   3.1    1.8  2  DUF3561        Protein of unknown function (DUF3561)


Domain annotation for each model (and alignments):
>> Ribophorin_II  Oligosaccharyltransferase subunit Ribophorin II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   96.0   0.0   2.4e-31   2.1e-27     381     628 ..      28     275 ..      14     278 .. 0.85

  Alignments for each domain:
  == domain 1  score: 96.0 bits;  conditional E-value: 2.4e-31
  Ribophorin_II 381 aeisvadsdqsiapkktkvsypsklkksleadslqklrlkfalkdanegkeltphQafvrLthqktkqeviFvaeadskksYkfdldlgelaeefd 476
                    a++sv+ + + + + k++++ ++ l++ l++  +   +lk+ l+ ++ +++ +phQaf+ L+ ++t+ +  + +  +++ + k++l  ++  ++f 
     EEA21894.1  28 ATVSVSSKSA-TGKVKQSLKENAPLATPLSLGDSD--SLKLLLTAQEGRSAKRPHQAFLLLKDSTTGLDFSYPFSVKNDGKSKVELRKKDIPTQFL 120
                    4555554433.335566666666666666655555..4677888887889999******************999999999**************** PP

  Ribophorin_II 477 ylSGtYeveLivGDavlenpilwnvadvelkfpeeeekakkkkkkslykpkpeIkHlFRepekrPpkvvsntFtaLvllPllillvlwlklgvNls 572
                      S   ++e+++G    +   +   +++++  ++ +     + + ++y+ +p I+H+F+++ k Pp+++ ++F++ vl+ + +l  +w+ ++vNl+
     EEA21894.1 121 VTSEPVDAEIVIGSFGDSDAYRNLAFQLSIAGDASAP--AASDSVERYGKQPRINHVFKTDPKSPPQIITLIFLLTVLVTIPVLAGMWMYFDVNLN 214
                    ************9666555555555555555544444..4456999************************************************** PP

  Ribophorin_II 573 nfpfs.....lsailFhlglgaillLyvlFWlkLnmftTlkyLallgiftflvGnrlLssl 628
                    +++++     +  ilF+ +++++ ++++++++++n+f+ l + +++g++ fl+G r+Ls++
     EEA21894.1 215 HLTVAlkaapIPHILFVSSVIGLEGIFFMYYTSWNLFQMLPASLIVGVVAFLSGSRALSEV 275
                    ****99999999***********************************************98 PP

>> DUF3561  Protein of unknown function (DUF3561)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.2      0.34     3e+03      66      81 ..     194     209 ..     187     232 .. 0.49
   2 ?   11.3   3.1     3e-05      0.27      45      76 ..     234     265 ..     215     275 .. 0.72

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.34
     DUF3561  66 PvsvlvGvalsvllrg 81 
                  v v + v   +++  
  EEA21894.1 194 TVLVTIPVLAGMWMYF 209
                 3333333333333333 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 3e-05
     DUF3561  45 lyGsntlffllyt.WPfflallPvsvlvGvals 76 
                 + G + +ff+ yt W +f  +lP s++vGv+  
  EEA21894.1 234 VIGLEGIFFMYYTsWNLF-QMLPASLIVGVVAF 265
                 3466678*****956666.789*******9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (284 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       503  (0.0280551); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.38
# Mc/sec: 2230.41
//
Query:       EEA21895.1  [L=213]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (213 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       380  (0.0211947); expected 358.6 (0.02)
Passed bias filter:                      234  (0.0130515); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.36u 0.28s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1579.73
//
Query:       EEA21896.1  [L=293]
Description: short chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.9e-56  190.6   0.6    3.5e-56  190.4   0.6    1.1  1  adh_short_C2   Enoyl-(Acyl carrier protein) reductase
    5.5e-46  156.5   2.2    6.8e-46  156.2   2.2    1.1  1  adh_short      short chain dehydrogenase
    9.1e-14   51.8   0.5    1.3e-13   51.2   0.5    1.1  1  KR             KR domain
      0.004   16.6   0.1     0.0056   16.2   0.1    1.2  1  Epimerase      NAD dependent epimerase/dehydratase family
  ------ inclusion threshold ------
      0.047   13.1   0.2        0.1   12.0   0.0    1.6  2  GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  190.4   0.6   9.7e-60   3.5e-56       1     232 [.      49     289 ..      49     291 .. 0.92

  Alignments for each domain:
  == domain 1  score: 190.4 bits;  conditional E-value: 9.7e-60
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGH...HHHHHHHHHHTTSEE..EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-H CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneea...kkrveelaeelgaev..lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsr 92 
                   Ga +g+G   A+al e+Ga v + d+  e     +r+++ a+ lg+++   ++DV+d+e +++++ee+++  g++D+l+ +agi ++  +p+le s 
    EEA21896.1  49 GAGRGLGLVQAEALLEAGAIVYALDRLPEPsedFARIQAKASTLGTKIeyRRIDVRDTELLTNVIEEIANVEGRMDGLIAAAGIQQE--TPALEYSA 143
                   889**********************98888322345555666677886779************************************..******** PP

                   HHHHHHHHHHTHHHHHHHHHHHH.HCT..SCCEEEEEEEGGGTSBSTTTT..HHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGS.T CS
  adh_short_C2  93 eefdraldvnlyslfllakaalp.lmk..eggsivnlssvgaervvpnyn..aygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgi.k 183
                   ++ +++++vn++++f++a+a+++ +++  +ggsiv ++s++++++ ++    ay+a+Kaa+++l r+lA+e+g+++iRvN++spg+i T++++++  
    EEA21896.1 144 KDANTMMEVNVTGVFMTAQAVAKqMIRfgNGGSIVMIASMSGTIANKGLIcpAYNASKAAVIQLGRNLAAEWGQYNIRVNTISPGYIVTQMVENLfV 240
                   ***********************75442256**************9998888***************************************888625 PP

                   THHHHHHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEESTT CS
  adh_short_C2 184 gfdelleelearaplgrlgtpeevaeaalfLasdeasyitGqtlvvDgG 232
                   + +e +ee+ ++ +lgrl +pee   aa+fL+sd++s++tG++l +DgG
    EEA21896.1 241 QYPERREEWPKQNMLGRLSRPEEYRGAAVFLISDASSFMTGSDLRMDGG 289
                   599********************************************** PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  156.2   2.2   1.9e-49   6.8e-46       1     191 [.      43     239 ..      43     243 .. 0.92

  Alignments for each domain:
  == domain 1  score: 156.2 bits;  conditional E-value: 1.9e-49
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT...TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGC CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee...gakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfsel 96 
                 kvv+v Ga++G+G+  a++l+++Ga v+++dr +e+ e  a    ++   g+k+ + ++Dv+d e + +++e++++  g++d L++ AGi++ +p+ e+
  EEA21896.1  43 KVVCVSGAGRGLGLVQAEALLEAGAIVYALDRLPEPSEDFARIQAKAstlGTKIEYRRIDVRDTELLTNVIEEIANVEGRMDGLIAAAGIQQETPALEY 141
                 89*******************************99988766533333467************************9999********************* PP

                 SHHHHHHHHHHHTHHHHHHHHHHHHHHH.HCTTEEEEEEEEGGGTSB-TT..BHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHHC CS
   adh_short  97 seeewervievNltgvflltravlpaml.kqssGrIvnvsSvagkvpvag..vaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakelr 191
                 s+++ + ++evN+tgvf++++av+++m+  +++G+Iv ++S+ g  +++g   +aY AsKaav++l r+la e+ +++irvn++ PG++ T+m+++l 
  EEA21896.1 142 SAKDANTMMEVNVTGVFMTAQAVAKQMIrFGNGGSIVMIASMSGTIANKGliCPAYNASKAAVIQLGRNLAAEWGQYNIRVNTISPGYIVTQMVENLF 239
                 ****************************8899************77766611689**************************************99875 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.2   0.5   3.7e-17   1.3e-13       4     146 ..      46     192 ..      44     212 .. 0.90

  Alignments for each domain:
  == domain 1  score: 51.2 bits;  conditional E-value: 3.7e-17
                 EEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT--H CS
          KR   4 litGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklleemta 102
                  + G+  gLGl+ a+ l+e ga  +  l R ++++ed ++  a+ + lg+++e++++Dv d + +++++eei + e+++ G i aAg+ ++++  e +a
  EEA21896.1  46 CVSGAGRGLGLVQAEALLEAGAI-VYALDRLPEPSEDFARIQAKASTLGTKIEYRRIDVRDTELLTNVIEEIANVEGRMDGLIAAAGIQQETPALEYSA 143
                 689******************95.678899999999999888889999*************************************************** PP

                 HHHHHHHTTTTHHHHHHHHHTTTS--SE.....EEEEEEHHHHH--TT- CS
          KR 103 edleqvlapKvkGawnLhelledesldf.....fvlfSSiagllgsagq 146
                 +d +++++  v+G+    ++++++ + f     +v+++S++g++ ++g 
  EEA21896.1 144 KDANTMMEVNVTGVFMTAQAVAKQMIRFgnggsIVMIASMSGTIANKGL 192
                 ********************99966555444449*********999985 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.1   1.6e-06    0.0056       1     161 [.      45     216 ..      45     241 .. 0.80

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.6e-06
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC.........EEEE--TT-HHHHHHHHHH....H.T-SEEEE--S.---HHH...HH CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl.........elveldltdrsalerlfke....e.qpdavihlAa.vggvaa...ss 81 
                 ++V Ga   +G   ++alle+g  v +ldrl++ s+  ++ ++         e  ++d++d + l+++++e    e ++d  i +A+ ++  +a   s+
  EEA21896.1  45 VCVSGAGRGLGLVQAEALLEAGAIVYALDRLPEPSEDFARIQAkastlgtkiEYRRIDVRDTELLTNVIEEianvEgRMDGLIAAAGiQQETPAleySA 143
                 68999999999999*****************887665444444699******9999*****9966666654222236899******9877665433388 PP

                 HSHHHHHHHHTHHHHHHHHHHHHHTCTEEEEEEEGGGGTSCSS.SSBSTCSTTS----SSHHHHHHHHHHHHHHHHHHHHT CS
   Epimerase  82 edpadfieknlqgtlnlleaarkagvkrllflsSsevYGkdae.qpkeettltgplkpnspYaaaKlageklveayaaqyg 161
                 +d++ ++e n+ g+   ++a+ k+ + r+ + +S  +   +   +  ++ +         +Y a+K+a+ +l +++aa+ g
  EEA21896.1 144 KDANTMMEVNVTGVFMTAQAVAKQMI-RFGNGGSIVMIASMSGtI-ANKGL------ICPAYNASKAAVIQLGRNLAAEWG 216
                 99999999**************9999.*******88888888823.22222......4678**********9999999886 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   2.8e-05       0.1      13     113 ..      58     164 ..      51     183 .. 0.76
   2 ?   -3.5   0.0       1.4   5.2e+03     153     176 ..     197     220 ..     196     241 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 2.8e-05
                    HHHHHHHCT-CCEEEEEEES.S-TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHHHH.....T-SEEEE--S---....HHHHTTSHHHH CS
  GDP_Man_Dehyd  13 laelLlekgyevhgivrrss.sfntgriehlakdpkeeleenlklhkgDltDssslerllaev.....qpdevynLAAqsh....VdvsfekPeyt 98 
                     ae Lle g  v+ ++r+ + s +++ri++ a+     l ++++  + D++D++ l+++++e+     ++d  +  A+        ++s +++ ++
     EEA21896.1  58 QAEALLEAGAIVYALDRLPEpSEDFARIQAKAS----TLGTKIEYRRIDVRDTELLTNVIEEIanvegRMDGLIAAAGIQQetpaLEYSAKDANTM 149
                    5899*************8751556788877554....56789*******************99666666777777776542233377788888888 PP

                    HHHHTHHHHHHHHHH CS
  GDP_Man_Dehyd  99 aevnvlGtlrLLeai 113
                    +evnv+G++   +a+
     EEA21896.1 150 MEVNVTGVFMTAQAV 164
                    888888877665555 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 1.4
                    HHHHHHHHHHHHHHHHHHH---EE CS
  GDP_Man_Dehyd 153 YaaaKlyadwivvnyreayglfav 176
                    Y a+K++  ++ +n   ++g + +
     EEA21896.1 197 YNASKAAVIQLGRNLAAEWGQYNI 220
                    888999888888888877776544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (293 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       398  (0.0221987); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 1956.16
//
Query:       EEA21897.1  [L=632]
Description: lysophospholipase Plb1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   7.2e-186  618.4   4.2   8.5e-186  618.1   4.2    1.0  1  PLA2_B    Lysophospholipase catalytic domain
  ------ inclusion threshold ------
       0.12   12.9   0.2         23    5.6   0.0    2.7  2  PSD3      Protein of unknown function (DUF1587)


Domain annotation for each model (and alignments):
>> PLA2_B  Lysophospholipase catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  618.1   4.2  9.5e-190  8.5e-186       1     491 []     105     587 ..     105     587 .. 0.98

  Alignments for each domain:
  == domain 1  score: 618.1 bits;  conditional E-value: 9.5e-190
      PLA2_B   1 iaiavSGGGyramltgaGvlkAldsRtdnat...glgGlLqsatYlaGlsGgsWlvgslavNnftsvqelskkkeddsvweleksiln.p..eglelvk 93 
                 +aiavSGGGyramltg+G+lkA+dsRt n+t   ++gGlLqsatY++GlsGgsWl++s++vNnft++ +l++ ++  + w+l +sil+ p  +g++l++
  EEA21897.1 105 VAIAVSGGGYRAMLTGGGALKAFDSRTPNSTssgQIGGLLQSATYVSGLSGGSWLLASIYVNNFTTIGDLQA-DGVGEAWQLGNSILEgPsrGGFQLLS 202
                 79*************************99998999*************************************.68889*********9757799***** PP

      PLA2_B  94 nikrydeivdevekKkdagfnvsltDiwGralseklveaeeggvnltlsslkdaekfqeaemplPiivadgrkpgetvinlNatvfEfsPyelgswdak 192
                 ++++y+ i+d+v+ K+dag+n++ltDiw+r+ls ++++a++gg+++t+ss++ +++f ++ +p+P++vad r p et++ +N+tv+EfsP+e+gswd++
  EEA21897.1 203 SAEYYNTISDQVQAKSDAGYNTTLTDIWARMLSFQFINATDGGPSYTWSSIALESNFASGSIPMPLVVADLRSPSETIVGTNSTVMEFSPFEFGSWDPT 301
                 *************************************************************************************************** PP

      PLA2_B 193 lnsFvpveylGtklsnGtvvkkgkcvagfdnaGflmgtsstlFnevlleinstsmlesllkellkkllkdlsedsedisqyapnpfkdaeeenqnatqs 291
                 + +F p+eylG+k++nG+ +++++cv+g+dnaGf+ gtsstlFn ++l +ns+  l+++l++l+++ l++l +d+edi+ y  npf++++    + t  
  EEA21897.1 302 IYGFSPLEYLGSKFNNGSLPQDHSCVRGYDNAGFVFGTSSTLFNDFILYVNSSG-LPNVLEHLITNALNQLGRDNEDIADYV-NPFYNYT----QNTGL 394
                 *****************************************************9.***************************.******9....77889 PP

      PLA2_B 292 ivesktLdlvdggedgqniplvpllqkerevdvifaldnsadteeswpdgvslvatyeRvle.skqvkgkkfpyvpdqntfvnlgLnkrptffGcDarn 389
                 +++++tL +vdgged qnipl pl+q++r+vdvifa+d+sadt++swp+g+slv tyeR l+ s  ++g++fp+vpdq+tf+n gLn++ptffGc ++n
  EEA21897.1 395 VAQTETLSVVDGGEDYQNIPLYPLIQPTRHVDVIFAVDSSADTNDSWPNGASLVYTYERSLNsSGIGNGTSFPAVPDQDTFINKGLNTHPTFFGCNSSN 493
                 999***********************************************************77889******************************** PP

      PLA2_B 390 ltdlsatvdestpPlvvylpnekysylsnlstfklsykdseregliengfeaatqdnetdddefaacvacaiirRklerknltlpsecekcFedycwng 488
                 +            Pl+vy+pn++y ++snlst +ls++++er++li+n++ +at+ n t d+++ acv+ca++ R++er+n+t p+ c++cF++ycw+g
  EEA21897.1 494 TSTP--------TPLIVYIPNYPYVAYSNLSTLTLSINNTERDALIQNAYDMATMANGTRDPDWPACVGCAMLGRSFERTNTTVPDICNTCFDRYCWDG 584
                 9998........9************************************************************************************** PP

      PLA2_B 489 tvd 491
                 t++
  EEA21897.1 585 TTN 587
                 975 PP

>> PSD3  Protein of unknown function (DUF1587)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0    0.0026        23       2      19 ..     200     217 ..     199     228 .. 0.83
   2 ?    4.5   0.0    0.0054        49      25      52 ..     319     347 ..     311     350 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0026
        PSD3   2 RLtraEYenTvrDLlgvd 19 
                  L+ aEY nT+ D ++ +
  EEA21897.1 200 LLSSAEYYNTISDQVQAK 217
                 69***********77655 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.0054
        PSD3  25 slpaDpa.segFdnnasalsvspllleqY 52 
                 slp+D + ++g+dn + +  +s++l++ +
  EEA21897.1 319 SLPQDHScVRGYDNAGFVFGTSSTLFNDF 347
                 79**************9999999998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (632 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       423  (0.0235931); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 4013.81
//
Query:       EEA21898.1  [L=1368]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1368 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1215  (0.0677673); expected 358.6 (0.02)
Passed bias filter:                      262  (0.0146132); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.98u 0.27s 00:00:01.25 Elapsed: 00:00:00.47
# Mc/sec: 8662.72
//
Query:       EEA21899.1  [L=545]
Description: allantoin permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.2e-102  344.0  43.9   1.3e-102  343.8  43.9    1.0  1  Transp_cyt_pur  Permease for cytosine/purines, uracil, thiami
  ------ inclusion threshold ------
       0.45   10.2   2.9       0.53    9.9   1.0    2.2  1  Endothelin      Endothelin family


Domain annotation for each model (and alignments):
>> Transp_cyt_pur  Permease for cytosine/purines, uracil, thiamine, allantoin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  343.8  43.9  1.5e-106  1.3e-102       1     439 [.      34     485 ..      34     486 .. 0.97

  Alignments for each domain:
  == domain 1  score: 343.8 bits;  conditional E-value: 1.5e-106
  Transp_cyt_pur   1 pvpeeeRtwktlnlfsiWlganlnintwvigalglalgLnwwqsvlviivgnligaifvallglaGakyGlpfpilsRasfGirgsllplllrvv 95 
                     pv+  +R+w+ + + + W+  n ni+t+++g++++ lgL+wwq++++i++gn+++ +f++l++l Ga y+l fp+  R++ G +gs + + +r++
      EEA21899.1  34 PVEAGRRKWGFWTFNYYWVLINCNISTYMTGSSLIPLGLSWWQAIIAIVIGNILASVFIVLNSLPGAFYHLGFPVANRYVWGMWGSQWVICNRIF 128
                     89999****************************************************************************************** PP

  Transp_cyt_pur  96 iaivwfgvqawiGsealllmlgkifgk.wleigg...ailgtsltelvtffifwvvslvivllgvskirkffviaallvpvaafgfliwalvkae 186
                     + i+w++ qawiG+e++++ l+ i+++ +++i++   a+ g+++ e+v+ ++f v+sl++v++ ++k++ +f i a++v v+ +++liw l+  +
      EEA21899.1 129 LSIIWYACQAWIGGECVYVCLQAIWPSlEDRIPNhmpASTGMTTAEFVAYIVFMVISLPFVYVRPHKLQLLFYISAAVVLVFEVVLLIWSLATMG 223
                     ************************************9****************************************************877665 PP

  Transp_cyt_pur 187 g...Gpvldkavklgkse.lflsavagvlagfatlilnapDFtryaktkkssvkiqlvavpllftlllligilvaaaakaayganawspldilak 277
                         G+ ++  ++++    +++ ++++ +++ a+ iln  D++r+a++++ ++++q+++ +l++++  +igilv+aa++  yg+ +w+ +++l  
      EEA21899.1 224 DvgfGDTISSTTSSS--GwMIAYGIISTIGSIAAGILNQTDYARFARKPRDAIYGQIISSALCAISCGVIGILVTAATQNRYGEAMWNLPNLLSA 316
                     556699888666666..325778************************************************************************ PP

  Transp_cyt_pur 278 fdet......agvllililvalaqlgvnisanllsagldlaallPkkinikrgsliaavialvivpwkllssssklftaflsllavflspvagvi 366
                     + et      a+ ++  + + ++q+gvn+ +n ls g+d+aa  Pk+ini+rg++ + +i+++  pwkl +++++ f++ ls ++vf++p++g +
      EEA21899.1 317 IIETggsrsrAAAFFGGVALVVSQIGVNVPGNALSGGFDFAATWPKYINIRRGAYLTVLISIAANPWKLVNTATT-FLTVLSSYSVFVGPMVGLM 410
                     ***************************************************************************.******************* PP

  Transp_cyt_pur 367 iadyfvvrrgylklaalytrrrgsaYwyrkgvNwravaayivGiaaglvgvagsvg..ikvvkgaeklfdlsylv 439
                     i  y+vv ++++k+ +l+  +++s+Ywy++gvNwrav+a+i+G+a++l+g+++ v   i+v+ g++ l+++ +l 
      EEA21899.1 411 ISSYLVVNQRKIKVPDLFIGNKNSIYWYTYGVNWRAVVAWICGVAPSLPGFIAYVNpnISVPIGLTHLYYICFLT 485
                     ****************************************************988899***********998765 PP

>> Endothelin  Endothelin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   1.0   5.9e-05      0.53       6      25 ..     135     153 ..     134     154 .. 0.89

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 5.9e-05
  Endothelin   6 sCsnllDkECvYFCHLdIiW 25 
                 +C+ +   ECvY C L  iW
  EEA21899.1 135 ACQAWIGGECVYVC-LQAIW 153
                 5*************.77777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (545 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       662  (0.0369234); expected 358.6 (0.02)
Passed bias filter:                      261  (0.0145574); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 3591.68
//
Query:       EEA21900.1  [L=1011]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.1e-116  389.6   0.1     3e-116  388.1   0.0    1.8  2  DUF917          Protein of unknown function (DUF917)
    1.6e-28   99.8   6.2      8e-23   81.1   0.5    3.5  3  Hydantoinase_A  Hydantoinase/oxoprolinase
    3.1e-25   88.9   8.9    3.1e-24   85.7   0.1    3.6  4  Hydant_A_N      Hydantoinase/oxoprolinase N-terminal region
    0.00039   19.1   3.2       0.31    9.6   0.0    2.4  2  MutL            MutL protein
     0.0061   16.1   0.5     0.0061   16.1   0.5    2.2  2  BcrAD_BadFG     BadF/BadG/BcrA/BcrD ATPase family
  ------ inclusion threshold ------
      0.016   14.7   0.2      0.046   13.2   0.2    1.8  1  ROK             ROK family
        6.3    7.3   6.4        8.6    6.8   0.7    3.5  4  FtsA            Cell division protein FtsA


Domain annotation for each model (and alignments):
>> DUF917  Protein of unknown function (DUF917)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0      0.76   1.9e+03      38     101 ..     138     203 ..     132     206 .. 0.74
   2 !  388.1   0.0  1.2e-119    3e-116       2     350 .]     618     995 ..     617     995 .. 0.96

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 0.76
                 EEEE-GGG--S......EE..EEEEEEE-HHHHTT-SS-HH....HHHHHHHHHT--EEEEE-SSSSCCH CS
      DUF917  38 vrvvsldelpd......dalvvvvgamGsptvieeklpsgdelleavealekllgrkidavislEiGGlN 101
                 +  +s+++++d      +a + +v+++G  +++ ++  +++    a+++++  l+ +++ v+s  iG+++
  EEA21900.1 138 ISAISPNQIKDtvaeikKAGISTVALVGVFSPLDHQGTQEE----ACKKMMLELDPSLSVVCSSKIGNVG 203
                 66677777777777776777899999999999999997777....6677777777778888888888765 PP

  == domain 2  score: 388.1 bits;  conditional E-value: 1.2e-119
                 GHHHHHHHHHHTTTT-SS-HHHHHHHHTT-SBTT..-.-EEEE-GGG--SEE..EEEEEEE-HHHHTT-SS-HH....HHHHHHHHHT--.EEEEE-SS CS
      DUF917   2 dlealatGaavLGtGGGGspysgylllrqaleeg..k.svrvvsldelpddalvvvvgamGsptvieeklpsgdelleavealekllgrk.idavislE 96 
                 dle++atG++vLGtGGGG+ y +yl++ + l++   k ++rvv ++ ++d +++v+++++G+p+v++e+lp+g+e+++a++   +l +++ ++avi+ E
  EEA21900.1 618 DLEFIATGTGVLGTGGGGPSYLQYLQCLHWLRSPesKgRMRVVAPEYMKDTDVCVFGSWYGAPSVSSERLPAGTEIMTAINYSVQLSKHShFEAVIADE 716
                 9*******************************5556679**********************************************998888******** PP

                 SSCCHHHHHHHHHHHHT-EEESB-SSSS--SSGGGSHHHHTT----SEEEE-SSS-EEEEEE.---HHHHHHHHHHCTTTTTEEEEEEEEE-HHHHHH- CS
      DUF917  97 iGGlNglvallaaaklglpvvDaDgmGRAfPelqqttfavagisltPlaladekgnvvllkkaqsdkavErllRaalvemgsfagvaaypmtgaelkra 195
                 iGG+Ng++++ +++ +++pv+D+D+mGRA+P++++ t++v+g ++tP++lad+k+nv ++ +a+s+ +vE +lR+ +v++g  ++vaa p++ + +k++
  EEA21900.1 717 IGGGNGMSTFPTSSFYDIPVIDGDLMGRAYPTMEHGTPYVYGYPITPCTLADAKQNVGVVMNAESNSRVEGMLRSQCVNLGLKTAVAAVPLSCDIIKEY 815
                 ******************************************************************99******************************* PP

                 -SBSHHHHHHHHHHHHHTT--...-SHHHHHHHHHH-EEEEEEEEE--------------EEEET......................EEEEEEESSSEE CS
      DUF917 196 avpgtlslalriGravaearea.kdvveailealgggakvlfkGkivdverrteggfdvgevtiegldede...............grelkiefqNEnl 278
                 ++p+t+s+a+ iGrav++ar++ +d+v++i++++ g  k+l++Gki+dv+r++++g+++g++tie l+ de               +r + i+fqNE+l
  EEA21900.1 816 CIPNTVSQAWYIGRAVHQARRSkTDIVKSIFATSPG--KLLYSGKIIDVKRDVSRGYTMGQCTIEPLTGDEienisttqstdeqkeKRCIVIPFQNEFL 912
                 ********************8855***********5..66******************************9**************99999********* PP

                 EEE....ET...........-SEETTSEEEEEHHB-SSSSB-TTTT.TS-EEEEEE---GGGS...SHHHH-S-....-....--- CS
      DUF917 279 lae..edge...........vlatvPDlIsvldaetgepigteelryGlrVtVlalpasekwr.teeglelvgPkaFGydleykpl 350
                 +a      +           v++tvPDlIsvl   +ge+ig++elryGlrV V+a++a+++w+  e+gl+++gP+ FG+d+e+k+l
  EEA21900.1 913 YAAyvD--NaidaddaskhdVICTVPDLISVL-GADGEAIGSQELRYGLRVDVIAMAAHPLWTgDERGLRVGGPQGFGLDMEFKSL 995
                 *99540..245666668888************.889**********************************************9975 PP

>> Hydantoinase_A  Hydantoinase/oxoprolinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.4   0.2   0.00088       2.3      78      99 ..       4      25 ..       1      90 [. 0.74
   2 !   81.1   0.5   3.1e-26     8e-23       1     173 [.     207     391 ..     207     394 .. 0.87
   3 !   12.8   0.0   2.1e-05     0.053     209     288 ..     400     476 ..     392     479 .. 0.91

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.00088
  Hydantoinase_A 78 ekkvItfDmGGTstDvslikdg 99
                    ++  I++D+GGT tD++ i+  
      EEA21900.1  4 SSYRIGVDVGGTNTDCAIIDVT 25
                    55679************99843 PP

  == domain 2  score: 81.1 bits;  conditional E-value: 3.1e-26
  Hydantoinase_A   1 rtetavvnAylspilreylesvekslekrgakarlmvmqsdGglvsadearkkpvetilSGPaaGvvgaaats.........klagekkvItfDm 86 
                     r +++++nA + ++ r++++ + k++++ + +++l++ q dG l++a++a + p++t +SGP  +++gaa+++         ++a +++++++D+
      EEA21900.1 207 RENATILNASILSLARKTARAFCKAMKDLQLHCPLFLTQNDGTLTDAATAAELPIKTFASGPTNSLTGAAYLAnldrgmgneEIAADTQILVMDI 301
                     7899*******************************************************************97222222222345577899**** PP

  Hydantoinase_A  87 GGTstDvslikdgevevsle..teiagvkvrlpaldirtvgagGgsil.vvdeggklrvgpesagadpgpacyrkGgteltvTDanlvLG 173
                     GGT+tDv+++    + ++     e++gv++ +   ++ +vg+gGgs + v    +++ vgp+s+g + g  +   Gg+ +t TD+ +  G
      EEA21900.1 302 GGTTTDVCALLPSGFPRKAPnfVEVGGVRTAFSIPEVLSVGLGGGSLVrVDEALDTVAVGPDSVGHRLGSDALVFGGNIMTSTDIVVASG 391
                     *******887655544443312677***********************7777889*****************************998766 PP

  == domain 3  score: 12.8 bits;  conditional E-value: 2.1e-05
  Hydantoinase_A 209 kveevAegilsvavenmanavrklsvergldpkeltlvvfGGaGaqhaaalaeelgvkkvivppyagvlsalGmalAdvr 288
                     kv+ + +++l +a +++++ +++ + + +     +tl+ +GG++ + a+ l    gv k i+pp+  +++a+G+a+A+v+
      EEA21900.1 400 KVKHIPDTVLVKARDKIKRILERTIDDMKISDLPVTLLLVGGGSIVCAESL---NGVAKCIIPPHHDSANAVGAAIAKVS 476
                     577888899999********************************9999988...79*********************986 PP

>> Hydant_A_N  Hydantoinase/oxoprolinase N-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.7   0.1   1.2e-27   3.1e-24       1     165 [.       7     173 ..       7     187 .. 0.88
   2 !    6.5   0.1    0.0024       6.2       3      18 ..     298     313 ..     296     332 .. 0.85
   3 ?    0.4   0.1      0.18   4.7e+02       9      56 ..     382     428 ..     377     441 .. 0.82
   4 ?   -3.2   0.3       2.3   5.8e+03     118     145 ..     474     500 ..     467     508 .. 0.72

  Alignments for each domain:
  == domain 1  score: 85.7 bits;  conditional E-value: 1.2e-27
  Hydant_A_N   1 rigIDvGGTfTDavaldeke......eevavlKllstpdavaegirealeevleesiprtskidvvrmGTTvatNallerkg...ervaLittkg.frd 89 
                 rig+DvGGT+TD+ ++d +       ++ a+ K+++t  +v++gi++a+ +vl +s  +++++++v +GTT+++Na++e +    ++va++   g f  
  EEA21900.1   7 RIGVDVGGTNTDCAIIDVTAtdntsrGVCASCKTPTT-PDVTSGIYTAIINVLAKSEVNRKDVQSVAIGTTHFVNAVVEADPrrlSKVAVVRLCGpFTR 104
                 79**************9877999**************.99***************************************66655588898888875677 PP

  Hydant_A_N  90 lleigrqnrpdlfelrikkplvlyeevvevderveadgevlkpldeeevrealkalkaagvesiavvllhSylnpe 165
                 ++    +  ++l        +++  +++ +d+++e+dg++++++  ++++ +++++k+ag++ +a v ++S+l  +
  EEA21900.1 105 AIPPFTDFPQRL-------REIMEGPIFYLDGGLEIDGREISAISPNQIKDTVAEIKKAGISTVALVGVFSPLDHQ 173
                 776666644444.......7899************************************************98764 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0024
  Hydant_A_N   3 gIDvGGTfTDavalde 18 
                   D+GGT TD++al +
  EEA21900.1 298 VMDIGGTTTDVCALLP 313
                 57**********9865 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.18
  Hydant_A_N   9 TfTDavaldekeeevavlKllstpdavaegirealeevleesiprtsk 56 
                 T TD+v+ +++ +   + K+   pd v    r+ +++ le++i+ + k
  EEA21900.1 382 TSTDIVVASGNADLGDASKVKHIPDTVLVKARDKIKRILERTID-DMK 428
                 89********9999999999999999998888888888888776.333 PP

  == domain 4  score: -3.2 bits;  conditional E-value: 2.3
  Hydant_A_N 118 evderveadgevlkpldeeevrealkal 145
                 +v++++++  e+l++ de +v ea+k+ 
  EEA21900.1 474 KVSGEIDV-IEILENRDERAVVEAAKQQ 500
                 67777777.6888888888888888764 PP

>> MutL  MutL protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.5   1.5   0.00026      0.68       4      71 ..      10      74 ..       8      86 .. 0.79
   2 !    9.6   0.0   0.00012      0.31     246     264 ..     292     311 ..     261     325 .. 0.76

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00026
        MutL  4 iDiGSttTkvtlvdlekvd...erllgqaeapTtveeedvleGleealeeleeklgktevdevlatSSAaG 71
                +D+G t T  +++d+ ++d     + ++ ++pTt    dv+ G+ +a+ ++ +k   +ev+++ + S A G
  EEA21900.1 10 VDVGGTNTDCAIIDVTATDntsRGVCASCKTPTTP---DVTSGIYTAIINVLAK---SEVNRKDVQSVAIG 74
                8**************99888866677778888887...8********9999888...35555555555555 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00012
        MutL 246 lg.dllvvDvGGaTTdvhsv 264
                 ++ ++lv+D+GG+TTdv + 
  EEA21900.1 292 ADtQILVMDIGGTTTDVCAL 311
                 33379************986 PP

>> BcrAD_BadFG  BadF/BadG/BcrA/BcrD ATPase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.5   2.4e-06    0.0061       1      73 [.       8      79 ..       8      91 .. 0.86
   2 ?   -2.6   0.2       1.2     3e+03       4      13 ..     300     309 ..     290     315 .. 0.69

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 2.4e-06
                 EEEEE-SSEEEEEEEETTTE.EEEEEEE--TTS-HHH.........HHHHHHHHHHT--GGGECEE..EEESTT CS
  BcrAD_BadFG  1 vGiDgGsTttkavlmdekge.vlgrgitnsanlesvrfeaaekvleealtealerageeeadieetylvgtgyG 73
                 +G+D+G+T t ++++d        rg++ s ++    + ++ + + +a+ ++l++++ +++d++++++++t + 
   EEA21900.1  8 IGVDVGGTNTDCAIIDVTATdNTSRGVCASCKTPT--TPDVTSGIYTAIINVLAKSEVNRKDVQSVAIGTTHFV 79
                 7***************8877577788877777765..559**************************99998765 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.2
                  EE-SSEEEEE CS
  BcrAD_BadFG   4 DgGsTttkav 13 
                  D+G+Ttt ++
   EEA21900.1 300 DIGGTTTDVC 309
                  6666666655 PP

>> ROK  ROK family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.2   1.8e-05     0.046       2      69 ..       8      80 ..       7      91 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.8e-05
                EEEEE-SSEEEEEEEETTS-EEEEEEE....EEH.CCHHCCHHHHHHHHHHCCCHCCHTEEEEEEEEESSEEE CS
         ROK  2 igidiGgtkialalvdeegeilarekv....etp.tetteetlvdaiaelvdeaerkadeliavgigspGlis 69
                ig+d+Ggt++ +a++d   +   ++ v    +tp t+++  ++  ai +++++ e + +++ +v+ig + +++
  EEA21900.1  8 IGVDVGGTNTDCAIIDVTATDNTSRGVcascKTPtTPDVTSGIYTAIINVLAKSEVNRKDVQSVAIGTTHFVN 80
                8**************988777777766777755414577888888888888888888889*******999985 PP

>> FtsA  Cell division protein FtsA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.7    0.0034       8.6       1      23 [.       8      35 ..       8     282 .. 0.85
   2 ?    1.7   0.0      0.14   3.5e+02       2      13 ..     298     309 ..     297     330 .. 0.87
   3 ?   -1.3   0.2       1.2   2.9e+03      73      73 ..     448     448 ..     358     573 .. 0.58
   4 ?   -3.7   0.0       6.4   1.6e+04      41      54 ..     827     840 ..     805     886 .. 0.75

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0034
                EEEEE-SSSEEEEEEETTEEEE.....E CS
                xxxxxxxxxxxxxxxxxxxxxx.....x RF
        FtsA  1 alvDiGagktdvavaedgalvh.....l 23
                ++vD+G++ td+a+++  a  +      
  EEA21900.1  8 IGVDVGGTNTDCAIIDVTATDNtsrgvC 35
                58*************9977666444443 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.14
                 EEEE-SSSEEEE CS
                 xxxxxxxxxxxx RF
        FtsA   2 lvDiGagktdva 13 
                 + DiG+++tdv 
  EEA21900.1 298 VMDIGGTTTDVC 309
                 78*******986 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 1.2
                 G CS
                 x RF
        FtsA  73 s 73 
                  
  EEA21900.1 448 E 448
                 1 PP

  == domain 4  score: -3.7 bits;  conditional E-value: 6.4
                 HT--HHHHHHHHHH CS
                 xxxxxxxxxxxxxx RF
        FtsA  41 lrtaveeAerikik 54 
                 ++ av++A r k++
  EEA21900.1 827 IGRAVHQARRSKTD 840
                 67778888888743 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1011 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       583  (0.0325172); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.80u 0.29s 00:00:01.09 Elapsed: 00:00:00.45
# Mc/sec: 6772.84
//
Query:       EEA21901.1  [L=1033]
Description: 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.7e-14   52.8   0.9    4.7e-14   52.1   0.9    1.3  1  Fungal_trans     Fungal specific transcription factor domain
    7.7e-14   51.3   0.0    1.5e-13   50.4   0.0    1.4  1  3Beta_HSD        3-beta hydroxysteroid dehydrogenase/isomeras
    4.7e-12   45.9   0.0    1.2e-11   44.6   0.0    1.7  1  Epimerase        NAD dependent epimerase/dehydratase family
    2.4e-09   37.3   0.0    4.3e-09   36.5   0.0    1.4  1  NAD_binding_10   NAD(P)H-binding
    1.7e-07   30.7   0.0     0.0024   17.1   0.0    2.5  2  NAD_binding_4    Male sterility protein
    5.1e-07   29.4   0.0    9.2e-07   28.6   0.0    1.4  1  GDP_Man_Dehyd    GDP-mannose 4,6 dehydratase
    7.4e-07   29.2  10.5    1.5e-06   28.3  10.5    1.5  1  Zn_clus          Fungal Zn(2)-Cys(6) binuclear cluster domain
    7.5e-07   28.9   0.0    1.6e-06   27.8   0.0    1.6  1  NmrA             NmrA-like family
     0.0018   17.5   0.0     0.0028   16.9   0.0    1.3  1  Polysacc_synt_2  Polysaccharide biosynthesis protein
  ------ inclusion threshold ------
      0.018   14.5   0.0      0.033   13.6   0.0    1.4  1  adh_short        short chain dehydrogenase


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.1   0.9   2.6e-17   4.7e-14      11     196 ..     528     711 ..     518     785 .. 0.82

  Alignments for each domain:
  == domain 1  score: 52.1 bits;  conditional E-value: 2.6e-17
  Fungal_trans  11 qfpilhkpsflpkt...ssenssksayaspllllailalGalfsesetkesnssltses...qefiafplraeilihedfsspssslwilqsLllle 101
                    ++ lh p+f  ++    s n  + +    +lll+i++l+al+s++e+ e+ + + s     ++ +++  r++ +   +++  ++ l+ lq +l+ +
    EEA21901.1 528 IYHALHIPTFQLQYdgfWSLNAAEIDLIWLALLLTIISLAALMSPKEYMEMLAMENSIGrdwAHVWHQASRQALYA-GEYELKPT-LTQLQVFLCTQ 622
                   567889999999998665556666666677888****************996555555489989999999986555.99999999.*********** PP

  Fungal_trans 102 lyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlp..LPcddddlwesd 196
                   +y + +   +     +g avr a+ +gL +n + ++         +  e rrR+ww   + D++ a++lGrppl++ s+ ++p    c+d d+ e++
    EEA21901.1 623 IYWLETKQHEVLNSALGQAVRNAQAIGLDKNRPGKN-------RLD-TELRRRIWWELIVDDCYQAMCLGRPPLIHPSSSEVPkpVHCNDVDVTETS 711
                   ****9999999999***************9999988.......444.67************************989999988844557777776655 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.4   0.0   8.4e-17   1.5e-13       1     228 [.       9     252 ..       9     260 .. 0.73

  Alignments for each domain:
  == domain 1  score: 50.4 bits;  conditional E-value: 8.4e-17
   3Beta_HSD   1 vvtGgaGFlGralvkeLvrleelkevrvlD..lrespell.eelskvnvkk.viegDvtdkdkleealegvdvvihlaslvdvagkltedeimkvnvkG 95 
                 +vtG++GF+G+++v +L+ ++   +vr +   l++++e+  ++ +  +  + v   D  +   l+ea++gvd+vih+as  + + +++e+e+    ++G
  EEA21901.1   9 LVTGSTGFIGAHVVDTLLARGL--KVRGATrsLAKGDEMIrSRPQYAGKLEfVQIQDFENPGGLTEAVDGVDAVIHVASPFNYHITDNEKELIIPAING 105
                 69******************95..66666545444444330333333333345556******************************************* PP

   3Beta_HSD  96 Trnvleacvka.gvrvlvYtSsae.vvgpnslgee...ilngd.......EeleyeslhqdaypesKalaEklvlkaNgrtlkngg.rlyTcaLRpagi 181
                  r +lea+ +a +++++v tSs   vv  n +g +    + +d       E    +s+++ ay  sK+ aE   l+a +  +k+ + ++  + L p ++
  EEA21901.1 106 VRFMLEAASNApSIQRVVITSSFAsVVDINRTGPPgftYTAADwnpltyeEAADPKSTPVVAYRGSKKYAE---LAAWD-FIKDKKpHFDIVTLCPPMV 200
                 ******9987659********97515555666544221222222122221666777889************...78999.9999999************ PP

   3Beta_HSD 182 yGegdkllvpllkqlaklglalfkigdeev......lsdrvYvgNvawahilA 228
                 +G+  + ++ +l +l  ++ al +i++ ++      +  ++ v  +a ah+ A
  EEA21901.1 201 FGPIAHPIK-SLDHLNESNAALWEIAQGSSpfptarVPFWIDVRDLATAHVEA 252
                 ***988765.6778888888888888766511111133456666666666655 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.6   0.0   6.6e-15   1.2e-11       1     231 [.       8     258 ..       8     265 .. 0.71

  Alignments for each domain:
  == domain 1  score: 44.6 bits;  conditional E-value: 6.6e-15
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC......EEEE-.-TT-HHHHHHHHHHHT-SEEEE--S---HHHHHHSHHHHHHHHT CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl......elvel.dltdrsalerlfkeeqpdavihlAavggvaassedpadfieknl 92 
                 +lVtG tGfiG+++v+ ll++g +v g +r   ++ +  + +       e+v++ d+ ++  l+++++  ++davih+A   +++ + +++ ++i   +
  EEA21901.1   8 VLVTGSTGFIGAHVVDTLLARGLKVRGATRSLAKGDEMIRSRPqyagklEFVQIqDFENPGGLTEAVD--GVDAVIHVASPFNYHITDNEK-ELIIPAI 103
                 79****************************966655544444389**774444436777778888888..9*******9965555554444.456679* PP

                 HHHHHHHHHHHHH.TCTEEEEEEE.GGGGT...........SCSS.SS..BSTCSTTS--.--SSHHHHHHHHHHHHHHHHHHHH..T-EEEEEEESEE CS
   Epimerase  93 qgtlnlleaarka.gvkrllflsS.sevYG...........kdae.qp..keettltgpl.kpnspYaaaKlageklveayaaqy..glnaiilrlfnl 172
                 +g++ +leaa+ a  ++r++  sS ++v               a+  p   ee +  +p   p  +Y  +K ++e  ++++ ++    +++++l +  +
  EEA21901.1 104 NGVRFMLEAASNApSIQRVVITSSfASVVDinrtgppgftyTAADwNPltYEEAA--DPKsTPVVAYRGSKKYAELAAWDFIKDKkpHFDIVTLCPPMV 200
                 ***********998899*******8888888888888887733333466445555..45569********************999455*********** PP

                 ESTT.S-TTSTTSHHHHHHHHHHTTS..SSEEEETTST-EEEEEEHHHHHHHHHHHHHHHTT CS
   Epimerase 173 yGpr.ngegevsrvipalirkilegk..qevtllgdgtalRdflyveDvaeaillvlehvda 231
                 +Gp  ++ ++ +++    +   ++ +  q    + +   +  +++v+D+a+a++ ++ + +a
  EEA21901.1 201 FGPIaHPIKSLDHLNESNA---ALWEiaQGSSPFPT-ARVPFWIDVRDLATAHVEAALRKEA 258
                 ***9333233444433222...22222223333331.2233478888888888877666454 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.5   0.0   2.4e-12   4.3e-09       1     102 [.      12     131 ..      12     161 .. 0.77

  Alignments for each domain:
  == domain 1  score: 36.5 bits;  conditional E-value: 2.4e-12
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHH.....CTTTCEEEE-.-TT-CCHHHHHHTT-SEEEES---TCC...HHHH......... CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpeklaele.....aeeglevveg.dvtdvedlaealkgadaVvsalggggk...deeg......... 77 
                     G tG +G ++v+ llarg ++v+  +R+ +k +e+       + +le v++ d++++  l+ea++g+daV+  +++ +    d+e          
      EEA21901.1  12 GSTGFIGAHVVDTLLARG-LKVRGATRSLAKGDEMIrsrpqYAGKLEFVQIqDFENPGGLTEAVDGVDAVIHVASPFNYhitDNEKeliipaing 105
                     89***************5.*********999987653333344799*999559*********************554444443333457886666 PP

                     HHHHHHHHHHC.T--EEEEEEETTTT CS
  NAD_binding_10  78 aknivdaakea.gvkRfvlvsaigvg 102
                     ++ +++aa +a  ++R+v+ s++ + 
      EEA21901.1 106 VRFMLEAASNApSIQRVVITSSFASV 131
                     7777888876626*******998654 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.1   9.6e-05      0.17       1      21 [.      10      30 ..      10      54 .. 0.84
   2 !   17.1   0.0   1.4e-06    0.0024      82     209 ..      71     206 ..      66     236 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 9.6e-05
                   EE-TTSHHHHHHHHHHHHHS- CS
  NAD_binding_4  1 lTGaTGFLGkvLlekLLrttp 21
                   +TG+TGF+G++++  LL +  
     EEA21901.1 10 VTGSTGFIGAHVVDTLLARGL 30
                   7****************8765 PP

  == domain 2  score: 17.1 bits;  conditional E-value: 1.4e-06
                    HHHHHH--EEEE--S..S-S.STTSSEEHHHHHHHHHHHHHHHTSSS--.-EEEEEE..GGGTTS-TTT--SSS-H......HHH--EEEETTTCC CS
  NAD_binding_4  82 qelaeevdviihsaA..tvnfdepykellrvNveGtrevlelakklkklkvllhvST..ayvngeregeveekvyeegekeekldederaklkglp 173
                     e ++ vd++ih+a   +++++++ kel+ + ++G+r +le a++  + + ++  S+  ++v+ +r+g     +y + + +  ++e++ + +    
     EEA21901.1  71 TEAVDGVDAVIHVASpfNYHITDNEKELIIPAINGVRFMLEAASNAPSIQRVVITSSfaSVVDINRTGPP-GFTYTAADWNPLTYEEAADPKSTPV 165
                    567899********94456778999*********************************888888888765.4455555555666666666666666 PP

                    CHHHHHHHHHHHHHHHHHHH..H---EEEEEE-EEE-...- CS
  NAD_binding_4 174 ntYeqsKalaEklvrearrr..sglpvvivRpsiitg...e 209
                     +Y  sK  aE    +  +    ++ +v + p+++ g   +
     EEA21901.1 166 VAYRGSKKYAELAAWDFIKDkkPHFDIVTLCPPMVFGpiaH 206
                    6**********987776644003444777778888775553 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.6   0.0   5.2e-10   9.2e-07       1     117 [.       9     117 ..       9     129 .. 0.73

  Alignments for each domain:
  == domain 1  score: 28.6 bits;  conditional E-value: 5.2e-10
                    EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE-.-TT-HHHHHHHHHHHT-SEEEE--S---HHHHTTSH CS
  GDP_Man_Dehyd   1 LiTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkg.DltDssslerllaevqpdevynLAAqshVdvsfekP 95 
                    L+TG +GfiG+++++ Ll++g +v g +r  ++ +    e ++++p+  + ++l++++  D ++   l+++++ v  d+v++ A     +   ++ 
     EEA21901.1   9 LVTGSTGFIGAHVVDTLLARGLKVRGATRSLAKGD----EMIRSRPQ--YAGKLEFVQIqDFENPGGLTEAVDGV--DAVIHVASPFNYHITDNE- 95 
                    9*************************877665544....34455554..578999998549999999****9998..9*****987655544344. PP

                    HHHHHHHTHHHHHHHHHHHHCT CS
  GDP_Man_Dehyd  96 eytaevnvlGtlrLLeairalg 117
                    ++ +   + G+  +Lea+ ++ 
     EEA21901.1  96 KELIIPAINGVRFMLEAASNAP 117
                    3344444778888888877664 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.3  10.5   8.1e-10   1.5e-06       2      35 ..     362     396 ..     361     400 .. 0.90

  Alignments for each domain:
  == domain 1  score: 28.3 bits;  conditional E-value: 8.1e-10
                 S-HHHHHCT---STSSSS-HHHHHCT..HHHCCCCT CS
     Zn_clus   2 aCdnCrkkKvKCdakkPaCsnCkkln..leCtfyse 35 
                 +C +Crk+K KCd+++P C++C++++   +C+ ++ 
  EEA21901.1 362 SCYPCRKHKLKCDRQIP-CQSCIRYQreDQCKENPA 396
                 8****************.*******99999997765 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0     9e-10   1.6e-06       1      83 [.       8      95 ..       8     142 .. 0.74

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 9e-10
                EEESSTTSHHHHHHHHHHHHHT-EEEEEES-S...-SHHHHHHHHST.TEEE.ES-TT-HHHHHHHHTT-SEEEE---GGS-HHHHHH CS
        NmrA  1 IlviGaTGrqGksvvrallkaghkvralvRdt...kselakslkeaG.velv.kgdlddkeslvealkgvdvvfsvtgfyskeiedgk 83
                +lv+G+TG +G++vv+ ll++g kvr  +R +   ++      + aG  e+v  +d ++   l ea++gvd+v+ v + ++ +i d  
  EEA21901.1  8 VLVTGSTGFIGAHVVDTLLARGLKVRGATRSLakgDEMIRSRPQYAGkLEFVqIQDFENPGGLTEAVDGVDAVIHVASPFNYHITDNE 95
                79******************************875444455567777358997789******************99886644444432 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.0   1.5e-06    0.0028       1     139 [.       8     138 ..       8     169 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 1.5e-06
                      EEEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH......-TTEEEE....E--TT-HHHHHHHTT..T-SEEEE------HHHHH CS
  Polysacc_synt_2   1 vlvtGagGsiGselvrqilkkkpkkiillerdElklyeiekeleeelkkkklkveivpvigdvrdkerlekaleelkvdvvfhaAAlKhVPlve 94 
                      vlvtG++G iG ++v+++l++   k++   r+  k +e+ ++   +++  kl++     i d ++   l++a++  +vd+v+h+A   +  +  
       EEA21901.1   8 VLVTGSTGFIGAHVVDTLLARGL-KVRGATRSLAKGDEMIRSR-PQYAG-KLEFV---QIQDFENPGGLTEAVD--GVDAVIHVASPFNYHIT- 92 
                      89*****************9987.5777888888888887765.44554.56554...8***************..*********98877665. PP

                      HSHHHHHHHHHHHHHHHHHHHHHT.T-SEEEEEEEGGGSS--SHHH CS
  Polysacc_synt_2  95 enpleaiktNvlgtenvieaaiea.gvkkvvliStDKAvnPtnvmG 139
                       n  e i   + g + ++eaa +a  +++vv+ S+   v  +n  G
       EEA21901.1  93 DNEKELIIPAINGVRFMLEAASNApSIQRVVITSSFASVVDINRTG 138
                      577899999**********99876489*****99988888888765 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.0   1.9e-05     0.033       2      61 ..       7      67 ..       6      83 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 1.9e-05
                EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-.TTTSH CS
   adh_short  2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqv.Dvtdr 61
                 vlvtG ++ IG  ++++l+++G kv  + rs +k  e++ +  + + k+ ++q+ D ++ 
  EEA21901.1  7 FVLVTGSTGFIGAHVVDTLLARGLKVRGATRSLAKGDEMIRSRPQYAGKLEFVQIqDFENP 67
                69*************************************9999988888877775355555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1033 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       586  (0.0326845); expected 358.6 (0.02)
Passed bias filter:                      481  (0.026828); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.79u 0.33s 00:00:01.12 Elapsed: 00:00:00.49
# Mc/sec: 6312.04
//
Query:       EEA21902.1  [L=232]
Description: O-acetyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
      3e-15   56.2   0.1    5.1e-15   55.4   0.1    1.4  1  Mac        Maltose acetyltransferase
    2.1e-14   52.6   6.3    1.1e-11   44.0   3.9    2.3  2  Hexapep    Bacterial transferase hexapeptide (six repeats)
      1e-12   47.6   5.8      2e-09   37.0   4.1    2.3  2  Hexapep_2  Hexapeptide repeat of succinyl-transferase


Domain annotation for each model (and alignments):
>> Mac  Maltose acetyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.4   0.1   8.5e-19   5.1e-15       1      52 [.      39     100 ..      39     102 .. 0.82

  Alignments for each domain:
  == domain 1  score: 55.4 bits;  conditional E-value: 8.5e-19
                 HHHTTS-BETTTSHHHHHHHHHHHHHHHHHHT.STTT-HHH..........HHHHHHHHSSBE CS
         Mac   1 KMlaGelYdafsDpeLvaeRlrarelcrryNq.trpsdkde..........RrelLrellGsv 52 
                 +M++G+lYdaf  peL++ R++ar++c ryN+ ++p +  e          R+  Lrel+G++
  EEA21902.1  39 RMISGMLYDAFV-PELAKSRFKARAWCNRYNTyFPPPEATElqshealanlRMTWLRELMGAT 100
                 8*********86.******************97755544444555556666**********87 PP

>> Hexapep  Bacterial transferase hexapeptide (six repeats)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.7   0.0   0.00025       1.5      20      34 ..     139     153 ..     139     155 .. 0.76
   2 !   44.0   3.9   1.8e-15   1.1e-11       2      35 ..     175     208 ..     174     209 .. 0.96

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00025
                 EEE-TTEEEETTEEE CS
     Hexapep  20 VkIGdnvkIgagvvi 34 
                 V+IGd+v  g++v i
  EEA21902.1 139 VTIGDRVMFGPNVSI 153
                 788888888888866 PP

  == domain 2  score: 44.0 bits;  conditional E-value: 1.8e-15
                 EEEETTEEE-TTEEEETTEEE-TTEEEETTEEEE CS
     Hexapep   2 tvIGsnvlIgpfaviggnVkIGdnvkIgagvvig 35 
                 +vIG++++Ig  +vi+++V+IG++++I+ag+v+ 
  EEA21902.1 175 VVIGDDCWIGGQVVILPGVTIGKGCTIAAGAVVS 208
                 89******************************97 PP

>> Hexapep_2  Hexapeptide repeat of succinyl-transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.9   0.0   9.9e-05      0.59       2      16 ..     139     153 ..     137     156 .. 0.82
   2 !   37.0   4.1   3.4e-13     2e-09       1      33 [.     174     208 ..     174     209 .. 0.96

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 9.9e-05
                 EEE-TT-EE-TT-EE CS
   Hexapep_2   2 viIGdnCliGanagi 16 
                 v+IGd++++G+n  i
  EEA21902.1 139 VTIGDRVMFGPNVSI 153
                 789999999999654 PP

  == domain 2  score: 37.0 bits;  conditional E-value: 3.4e-13
                 .EEE-TT-EE-TT-EE..SEEE-TT-EE-TT-EE- CS
   Hexapep_2   1 pviIGdnCliGanagi..GvslGdncvvgaGvvit 33 
                 pv IGd+C iG   +i  Gv++G++c+++aG v+ 
  EEA21902.1 174 PVVIGDDCWIGGQVVIlpGVTIGKGCTIAAGAVVS 208
                 8**************99****************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (232 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       255  (0.0142228); expected 358.6 (0.02)
Passed bias filter:                      246  (0.0137208); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.46
# Mc/sec: 1506.82
//
Query:       EEA21903.1  [L=433]
Description: beta-lactamase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-45  156.3   0.0    3.4e-45  154.7   0.0    1.7  1  Beta-lactamase  Beta-lactamase
  ------ inclusion threshold ------
       0.23   10.9   0.0       0.35   10.3   0.0    1.2  1  Peptidase_S11   D-alanyl-D-alanine carboxypeptidase


Domain annotation for each model (and alignments):
>> Beta-lactamase  Beta-lactamase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  154.7   0.0   3.8e-49   3.4e-45      16     317 ..      31     407 ..      14     418 .. 0.88

  Alignments for each domain:
  == domain 1  score: 154.7 bits;  conditional E-value: 3.8e-49
                     EEEEEEE.ETTEEEEEEEE...EEEETTTTEEESTTSBEEEGGGHHHHHHHHHHHHHHTTSSCTTSB..GGGTST...............TCTTG CS
  Beta-lactamase  16 Gvavavv.rdgkvvldkgg...GvadleggrpvtadtlfriaSvtKtftaaavlqlveeGkldLddp..VskylP...............efagp 89 
                     G++ + v r+g ++++++    G+a  +g  p+t dt+f +aS+tK++t++a +qlve+Gkl+Ldd   V+k  P                +  +
      EEA21903.1  31 GLVYCAVdRNGDILFNHASgsrGLAPFNGD-PMTLDTVFWMASCTKMITGIACMQLVEQGKLSLDDVqqVEKIAPelrdvkalegdlksgFKLVD 124
                     555555505556665555555444555555.**********************************953389*******************56666 PP

                     GGTTEBHHHHHTTHSSCSSSSTSTTCTSHHHTH.....HHHHHHHHHSBSSSSTTSCEE-SHHHHHHHHHHHHHHHTSHHHHHHHHHTTTTTTST CS
  Beta-lactamase  90 gkgkiTlrdLltHtsGlpdlfasdlleeaaada.....aellralatlppkyapGtkwgYsntgygllgellekvtgrsleqllreeilrpLgmk 179
                      +++iTlr+Ll+Ht+G+ + f++ +l+++         a  ++ +  lp+  +pGt++ Y    + ++g l+e++tg sl ++++++i++pLg k
      EEA21903.1 125 KDRGITLRMLLNHTAGFGYPFDNSKLRDYSLPIgydefAGNTDDILGLPLINQPGTMFDYGVNLD-WAGILVERITGLSLNEYFQKHIFAPLGIK 218
                     6666*************88877777777775559999************************9999.***************************** PP

                     TEESSTTGGGGGGBEEEEEEETCEEECSCETTHHHHC................TTTBEEEEHHHHHHHH.......................... CS
  Beta-lactamase 180 dtelgppesgdprdaagytgngpearappanlpaeae................gagglistardlarfl.......................... 232
                     d+++ p ++  +r+a++++++ ++   ++++l ++a                 g++g ++t+ d+++ +                          
      EEA21903.1 219 DISFFPGADMKRRLAYMHRREEDGSLHVTDHLYRFALmekkasdsgaeerfcsGGAGCFGTIGDYCKIIavllnngtcpktkaqilkpetvdemy 313
                     ******************9999999999999988888********************************************99999999999999 PP

                     .......HHHHHCCSSSSHHHHHHHHHHHTSEEEECTTEEEECECSSEEEEECCH....TEEEEEEESTEEEEEEEECGGTEEEEEEESBCSSHH CS
  Beta-lactamase 233 .......glalegglllsaetlaqltaklssgttrpagiraglglGwvladktga....pgtfghtGggygtyvfvdpeanlvvavltnrdppne 316
                               +++++ +++ +la+ ++ +  +++ ++ +++g+gl + l++        pg+ ++ G  ++ ++++d+e++++ ++ ++  p   
      EEA21903.1 314 kdqlpdlPRYINKPAQSAKPHLAKHAPVRPLPAHEDESTTEGWGLTFALNHNAKEsgrkPGSASWEG-IANLFWWADRESGVGGMIGSQILPY-G 406
                     9999999777889999999999999************************98777799**********.***************9998887775.5 PP

                     H CS
  Beta-lactamase 317 d 317
                     d
      EEA21903.1 407 D 407
                     5 PP

>> Peptidase_S11  D-alanyl-D-alanine carboxypeptidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   3.9e-05      0.35      33      74 ..      65     106 ..      62     132 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 3.9e-05
                    TS-BE-GGGHHHHHHHHHHHHHHTTSS-TTSEEE--GGGHGC CS
  Peptidase_S11  33 devveiASltKlmTaylvlealkkgklkeddkvtisedayal 74 
                    d+v  +AS tK++T +  ++ +++gkl +dd  ++ + a +l
     EEA21903.1  65 DTVFWMASCTKMITGIACMQLVEQGKLSLDDVQQVEKIAPEL 106
                    567779************************998887766655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (433 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       275  (0.0153383); expected 358.6 (0.02)
Passed bias filter:                      271  (0.0151152); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.48
# Mc/sec: 2738.88
//
Query:       EEA21904.1  [L=892]
Description: regulatory protein Ral2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-20   73.1   1.3    3.2e-08   33.5   0.0    4.7  4  Kelch_4   Galactose oxidase, central domain
    5.6e-16   57.9   0.9    5.1e-05   22.8   0.0    4.9  4  Kelch_1   Kelch motif
    2.5e-14   53.1   8.8    2.2e-09   37.4   0.0    5.5  5  Kelch_3   Galactose oxidase, central domain
      2e-13   50.1   9.8    2.6e-05   24.4   0.4    5.3  4  Kelch_6   Kelch motif
    2.8e-11   43.1   6.2    4.7e-05   23.3   0.0    4.1  4  Kelch_5   Kelch motif
    7.8e-11   41.5   3.2    0.00052   19.9   0.0    4.1  4  Kelch_2   Kelch motif


Domain annotation for each model (and alignments):
>> Kelch_4  Galactose oxidase, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.0     3e-09   9.1e-06       4      49 .]      57     109 ..      52     109 .. 0.89
   2 !   33.5   0.0   1.1e-11   3.2e-08       1      48 [.     110     174 ..     110     176 .. 0.94
   3 ?    4.2   0.0     0.015        45      16      46 ..     229     259 ..     223     262 .. 0.88
   4 !    4.8   0.0    0.0094        28      31      44 ..     370     383 ..     362     393 .. 0.88

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 3e-09
     Kelch_4   4 ghsatsipdgtiylfGGrgedg.....tllndlylldlstntWrrl...gslPs 49 
                 g+++t ++ +++y+fGGr+        +l +dly ldl  ++W+++   g+ P+
  EEA21904.1  57 GATTTILG-DKLYVFGGRSVSSsqshvQLTSDLYELDLIRRHWSKVdvsGDIPP 109
                 66777775.9**********99***********************988887775 PP

  == domain 2  score: 33.5 bits;  conditional E-value: 1.1e-11
     Kelch_4   1 pRaghsatsipdgtiylfGGrgedg................tllndlylldlstntWrrlgsl.P 48 
                 pR +hs+++++d ++++fGG ++ +                ++++d++++d+ t+tW+rl+++ P
  EEA21904.1 110 PRYFHSVCALGDTKLVCFGGMSPADstgstqqhgsdeqadvQVMSDIHIYDVITRTWTRLPAKdP 174
                 8**********************99***********************************65433 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.015
     Kelch_4  16 ylfGGrgedgtllndlylldlstntWrrlgs 46 
                 +++GG+ + +     + +++l + +W+  +s
  EEA21904.1 229 IVVGGQDTSNHYIEQISVFNLRSLKWTSTSS 259
                 789*****999***************98766 PP

  == domain 4  score: 4.8 bits;  conditional E-value: 0.0094
     Kelch_4  31 lylldlstntWrrl 44 
                 l++ldl + tW+r+
  EEA21904.1 370 LWALDLRSLTWSRI 383
                 8***********98 PP

>> Kelch_1  Kelch motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   5.9e-07    0.0018       3      42 ..      56     101 ..      54     101 .. 0.93
   2 !   22.8   0.0   1.7e-08   5.1e-05       4      43 ..     114     170 ..     110     172 .. 0.89
   3 !    8.3   0.0   0.00055       1.6      13      45 ..     227     260 ..     224     261 .. 0.93
   4 ?    3.3   0.0     0.021        61      27      42 ..     368     383 ..     347     384 .. 0.85

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 5.9e-07
                 BSEEEEEETTEEEEEEEBCS......SSBEEEEEEEETTTTEEEEE CS
     Kelch_1   3 agagavvvggkiYviGGsdg......gnalssvevyDpetntWrel 42 
                  ga+ + +g+k+Yv+GG++        + +s+++ +D+    W+++
  EEA21904.1  56 VGATTTILGDKLYVFGGRSVsssqshVQLTSDLYELDLIRRHWSKV 101
                 688999*********************************9999986 PP

  == domain 2  score: 22.8 bits;  conditional E-value: 1.7e-08
                 SEEEEEETTEEEEEEEBCS.................SSBEEEEEEEETTTTEEEEEC CS
     Kelch_1   4 gagavvvggkiYviGGsdg.................gnalssvevyDpetntWrelp 43 
                 + +++  ++k+ ++GG++                   + +s++ +yD+ t tW++lp
  EEA21904.1 114 HSVCALGDTKLVCFGGMSPadstgstqqhgsdeqadVQVMSDIHIYDVITRTWTRLP 170
                 344555678**********************************************99 PP

  == domain 3  score: 8.3 bits;  conditional E-value: 0.00055
                 EEEEEEEBCS.SSBEEEEEEEETTTTEEEEECCC CS
     Kelch_1  13 kiYviGGsdg.gnalssvevyDpetntWrelpsM 45 
                 ++ v+GG+d  + +   + v+++++ +W+  +s+
  EEA21904.1 227 EMIVVGGQDTsNHYIEQISVFNLRSLKWTSTSSL 260
                 578**************************98887 PP

  == domain 4  score: 3.3 bits;  conditional E-value: 0.021
                 EEEEEEETTTTEEEEE CS
     Kelch_1  27 ssvevyDpetntWrel 42 
                  s++++D+++ tW+++
  EEA21904.1 368 YSLWALDLRSLTWSRI 383
                 699**********985 PP

>> Kelch_3  Galactose oxidase, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.1       1.9   5.7e+03      33      47 ..      47      61 ..      41      62 .. 0.81
   2 !   37.4   0.0   7.4e-13   2.2e-09       1      48 [.      64     118 ..      64     119 .. 0.88
   3 !    8.6   0.0   0.00077       2.3      19      47 ..     154     184 ..     127     186 .. 0.84
   4 !    6.6   0.0    0.0034        10       2      41 ..     226     268 ..     225     272 .. 0.80
   5 ?    1.6   0.4      0.13   3.7e+02      19      35 ..     368     386 ..     351     401 .. 0.69

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 1.9
     Kelch_3 33 eiaslppaRaghaat 47
                ++++ p a +g+++t
  EEA21904.1 47 TTGREPRALVGATTT 61
                458999999999998 PP

  == domain 2  score: 37.4 bits;  conditional E-value: 7.4e-13
     Kelch_3   1 gdrlyifGGlgd....dgqdrlndvyvydldtntWaei...aslppaRaghaata 48 
                 gd+ly+fGG+      ++ + ++d+y++dl +  W ++   ++ pp+R++h+++a
  EEA21904.1  64 GDKLYVFGGRSVsssqSHVQLTSDLYELDLIRRHWSKVdvsGDIPPPRYFHSVCA 118
                 89**********6554445555**************99999*************8 PP

  == domain 3  score: 8.6 bits;  conditional E-value: 0.00077
     Kelch_3  19 ndvyvydldtntWaei..aslppaRaghaat 47 
                 +d + yd+ t tW+++   ++p +R+ h+at
  EEA21904.1 154 SDIHIYDVITRTWTRLpaKDPPLGRYAHCAT 184
                 67788***********8777888**999998 PP

  == domain 4  score: 6.6 bits;  conditional E-value: 0.0034
     Kelch_3   2 drlyifGGlgddgqdrlndvyvydldtntWaei....aslppaR 41 
                  ++ ++GG + +++ +  +  v++l + +W+++     s+ ++R
  EEA21904.1 226 AEMIVVGGQD-TSNHYIEQISVFNLRSLKWTSTsslgRSCGSYR 268
                 6799******.788888**************9845555556666 PP

  == domain 5  score: 1.6 bits;  conditional E-value: 0.13
     Kelch_3  19 ndvyvydldtntWaei..a 35 
                  +++++dl + tW +i  +
  EEA21904.1 368 YSLWALDLRSLTWSRIdgG 386
                 589***********99551 PP

>> Kelch_6  Kelch motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.1   7.7e-06     0.023       4      48 ..      57     109 ..      52     111 .. 0.81
   2 !   24.4   0.4   8.6e-09   2.6e-05       1      47 [.     110     175 ..     110     178 .. 0.92
   3 !    6.6   0.0    0.0034        10      16      46 ..     230     260 ..     221     264 .. 0.89
   4 !    7.3   0.1     0.002       6.1      10      43 ..     350     383 ..     349     388 .. 0.92

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 7.7e-06
     Kelch_6   4 ghslvsvggkiYifGGytds.....spylnkvwvydpetksWeqlp...plpv 48 
                 g ++++ g+k+Y+fGG++ s      + +++++ +d++ + W+++    ++p 
  EEA21904.1  57 GATTTILGDKLYVFGGRSVSssqshVQLTSDLYELDLIRRHWSKVDvsgDIPP 109
                 5567889************9999999999999999999999999733335655 PP

  == domain 2  score: 24.4 bits;  conditional E-value: 8.6e-09
     Kelch_6   1 praghslvsvgg.kiYifGGytds................spylnkvwvydpetksWeqlp..plp 47 
                 pr++hs+++ g+ k+++fGG + +                 +  +++++yd++t++W++lp  ++p
  EEA21904.1 110 PRYFHSVCALGDtKLVCFGGMSPAdstgstqqhgsdeqadVQVMSDIHIYDVITRTWTRLPakDPP 175
                 799******99889********99************************************966555 PP

  == domain 3  score: 6.6 bits;  conditional E-value: 0.0034
     Kelch_6  16 ifGGytdsspylnkvwvydpetksWeqlppl 46 
                 ++GG++ s+ y  ++ v+++++ +W+ +++l
  EEA21904.1 230 VVGGQDTSNHYIEQISVFNLRSLKWTSTSSL 260
                 889999999999**************99886 PP

  == domain 4  score: 7.3 bits;  conditional E-value: 0.002
     Kelch_6  10 vggkiYifGGytdsspylnkvwvydpetksWeql 43 
                 +++++++ G y  ss+   ++w +d+++ +W+++
  EEA21904.1 350 INNHLVVSGTYLTSSKQEYSLWALDLRSLTWSRI 383
                 799********9999999*************986 PP

>> Kelch_5  Kelch motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   5.5e-07    0.0016       2      39 ..      52      93 ..      51      94 .. 0.86
   2 !   23.3   0.0   1.6e-08   4.7e-05       1      41 [.     107     163 ..     107     164 .. 0.86
   3 ?    2.2   0.2     0.062   1.8e+02       2      13 ..     175     186 ..     174     196 .. 0.86
   4 ?   -3.5   0.2       3.9   1.2e+04      16      25 ..     227     236 ..     221     240 .. 0.72

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 5.5e-07
     Kelch_5  2 PppRaghcavtvsekiYvyGGkv...g.rdgsvsddvyvLdl 39
                P ++ g+ + ++++k+Yv+GG++   + +  ++++d+y Ldl
  EEA21904.1 52 PRALVGATTTILGDKLYVFGGRSvssSqSHVQLTSDLYELDL 93
                677788888999***********8753678999********8 PP

  == domain 2  score: 23.3 bits;  conditional E-value: 1.6e-08
     Kelch_5   1 iPppRaghcavtvs.ekiYvyGGkv............g...rdgsvsddvyvLdlps 41 
                 iPppR+ h++++++ +k+ ++GG++            +    d +v +d++++d+++
  EEA21904.1 107 IPPPRYFHSVCALGdTKLVCFGGMSpadstgstqqhgSdeqADVQVMSDIHIYDVIT 163
                 7************55**********99999998887525567888889999999986 PP

  == domain 3  score: 2.2 bits;  conditional E-value: 0.062
     Kelch_5   2 PppRaghcavtv 13 
                 P +R+ hca ++
  EEA21904.1 175 PLGRYAHCATIL 186
                 99******9876 PP

  == domain 4  score: -3.5 bits;  conditional E-value: 3.9
     Kelch_5  16 kiYvyGGkvg 25 
                 +++v GG ++
  EEA21904.1 227 EMIVVGGQDT 236
                 6889999886 PP

>> Kelch_2  Kelch motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   0.0   1.7e-07   0.00052       2      47 ..      55     103 ..      54     105 .. 0.93
   2 !   14.2   0.0     1e-05     0.031       2      48 ..     111     172 ..     110     173 .. 0.89
   3 !    5.5   0.0    0.0061        18       9      49 .]     223     261 ..     221     261 .. 0.88
   4 ?   -3.3   0.0       3.7   1.1e+04      31      44 ..     369     382 ..     351     384 .. 0.72

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 1.7e-07
     Kelch_2   2 rgghsssvpggkiyvvGGa...htdnpnlsssdvhvldlekhvWeevtp 47 
                 ++g +++ +g+k+yv+GG+    ++  +  +sd++ ldl  + W++v +
  EEA21904.1  55 LVGATTTILGDKLYVFGGRsvsSSQSHVQLTSDLYELDLIRRHWSKVDV 103
                 68999999*************************************9966 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 1e-05
     Kelch_2   2 rgghsss.vpggkiyvvGGa..............htdnpnlsssdvhvldlekhvWeevtpl 48 
                 r+ hs++  ++ k++ +GG               +++ ++ + sd+h++d  +++W++++++
  EEA21904.1 111 RYFHSVCaLGDTKLVCFGGMspadstgstqqhgsDEQADVQVMSDIHIYDVITRTWTRLPAK 172
                 5556666377**********************999999*********************987 PP

  == domain 3  score: 5.5 bits;  conditional E-value: 0.0061
     Kelch_2   9 vpggkiyvvGGahtdnpnlsssdvhvldlekhvWeevtplg 49 
                 ++g  ++vvGG   d +n++++ + v++l++ +W+ ++ lg
  EEA21904.1 223 YGGAEMIVVGGQ--DTSNHYIEQISVFNLRSLKWTSTSSLG 261
                 566778899999..*********************998765 PP

  == domain 4  score: -3.3 bits;  conditional E-value: 3.7
     Kelch_2  31 dvhvldlekhvWee 44 
                 +++ ldl++ +W++
  EEA21904.1 369 SLWALDLRSLTWSR 382
                 46778888888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (892 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       455  (0.0253779); expected 358.6 (0.02)
Passed bias filter:                      276  (0.0153941); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.66u 0.28s 00:00:00.94 Elapsed: 00:00:00.44
# Mc/sec: 6135.60
//
Query:       EEA21905.1  [L=361]
Description: hypothetical protein PMAA_056940 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
      0.014   14.2   0.4      0.014   14.2   0.4    1.9  2  Fungal_trans_2  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.4     8e-07     0.014      40     110 ..       2      67 ..       1      72 [. 0.93
   2 ?    0.2   0.3     0.014   2.5e+02     233     297 ..     218     278 ..     205     281 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 8e-07
  Fungal_trans_2  40 hallalsafhlqskgpkds.lereakrykslalkelqealaelsstlsrnekykdiLaaiLllcsieissgd 110
                      a+l+++a+hl+++ p++s + + ++++ +++++++++ l+++ ++        + L+   ll+s+ is++d
      EEA21905.1   2 SAILCVGAMHLATLCPQSSkYAHASMQLIVKTVQLFRRNLSRPFTRDH-----CEALIGAALLISY-ISWSD 67 
                     69*********88888888999**************************.....*************.99998 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.014
  Fungal_trans_2 233 qrllswkprssdlepdldeterasslskdltelfrlaaliylyrlvlglppsspevqelvkklle 297
                     ++l++++++s d+++  ++ ++ ss +     + r  + + ++ ++l+ +++sp v+++  ++ +
      EEA21905.1 218 TKLTTTQSTSLDHQTVASQQSARSSFE----YIIRRMSPLLCCAALLESTADSPTVKSCAEDIEQ 278
                     555666666666666666666666666....8899999999999999999999999999887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (361 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       432  (0.024095); expected 358.6 (0.02)
Passed bias filter:                      382  (0.0213063); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.38
# Mc/sec: 2819.54
//
Query:       EEA21906.1  [L=269]
Description: NAD dependent epimerase/dehydratase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (269 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       356  (0.0198561); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1759.54
//
Query:       EEA21907.1  [L=224]
Description: mitochondrial peroxiredoxin Prx1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.2e-31  107.1   0.0    8.8e-31  106.4   0.0    1.4  1  AhpC-TSA    AhpC/TSA family
      6e-16   58.5   0.0    8.7e-16   58.0   0.0    1.2  1  Redoxin     Redoxin
    5.5e-14   51.7   0.5      9e-14   51.0   0.5    1.4  1  1-cysPrx_C  C-terminal domain of 1-Cys peroxiredoxin


Domain annotation for each model (and alignments):
>> AhpC-TSA  AhpC/TSA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.4   0.0   1.5e-34   8.8e-31       2     122 ..      12     147 ..      11     149 .. 0.96

  Alignments for each domain:
  == domain 1  score: 106.4 bits;  conditional E-value: 1.5e-34
                 TSB----EEESTTCEEEECHHHTT.SEEEEEEESTST-CCHHHHHHHHHHCHHHCCCTTEEEEEEESSSCHHHHHHHHH-H.......SSEEEE-TTSH CS
    AhpC-TSA   2 gdkapdfelknadgetvslsdykg.kpvvlffypkdwcpvCttelpalaklyeefkergvevigvsvdspeshkkfiekes......lnfpllsDeegk 93 
                 g  ap+f++++ + ++++++++ g ++vvlf +p d++p Cttel a+akl +ef+++gv++ig+s+++++sh ++i++++      l+fp+++D ++k
  EEA21907.1  12 GSTAPNFKAETSK-GPIDFHEFIGdNWVVLFSHPDDFTPICTTELGAFAKLEPEFAALGVKLIGLSANNVDSHHAWIKDINevnkanLTFPIIADYDRK 109
                 889******9887.9*******555************************************************************************** PP

                 HHHHTT-EETT.........TTECSCEEEEE-TTSBEE CS
    AhpC-TSA  94 vakaygvlkee.........kglalratfvidkegkir 122
                 +a  y++l+ +           +++r++fvid+++kir
  EEA21907.1 110 IAYLYDMLDYQdttnvdqkgLPFTIRTVFVIDPNKKIR 147
                 ********999*******999999*************9 PP

>> Redoxin  Redoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.0   0.0   1.5e-19   8.7e-16       3     136 ..      12     155 ..      10     166 .. 0.88

  Alignments for each domain:
  == domain 1  score: 58.0 bits;  conditional E-value: 1.5e-19
                 TSBB---ECCEETTCEEEEEHHHHTTSE.EEEEEESTTT-HHHHHTHHHHHTHHHHHHCSTTTEEEEEESSSHHHHHHHHH......TT-TSEEEE-TT CS
     Redoxin   3 gdkaPdftlplaatdgnsvslsefkgkk.vvvnfvpgafcPtCsaehpyleklaellkekgvdvvavvadndafvkefwgk......eglkfpvlsDgs 94 
                 g++aP+f+   a t   +++ +ef g + vv+++ p  f+P C++e+ +++kl++++++ gv+ ++++a+n +   +++++       +l+fp+++D +
  EEA21907.1  12 GSTAPNFK---AETSKGPIDFHEFIGDNwVVLFSHPDDFTPICTTELGAFAKLEPEFAALGVKLIGLSANNVDSHHAWIKDinevnkANLTFPIIADYD 107
                 899*****...569*********888777999******************************************8888888888999************ PP

                 SHHHHHTT-TTEEE.GGG......EEE-EEEEEEETTEEEEEEESSSC CS
     Redoxin  95 aaftkalGlrleedaseg......lrtpryavidedgkvvylevepep 136
                  +++  +++   +d ++       + +++++vid ++k++ +   p +
  EEA21907.1 108 RKIAYLYDMLDYQDTTNVdqkglpFTIRTVFVIDPNKKIRLTLAYPAS 155
                 ********87666666669999*****************866555555 PP

>> 1-cysPrx_C  C-terminal domain of 1-Cys peroxiredoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.0   0.5   1.5e-17     9e-14       1      38 [.     169     206 ..     169     208 .. 0.96

  Alignments for each domain:
  == domain 1  score: 51.0 bits;  conditional E-value: 1.5e-17
                 HHHHHHHHT-BB-TTT.TBT-EEE---SSHHHHHHHHH CS
  1-cysPrx_C   1 ALQladkhgvatPAnWkpGdkvivpPpateedavkryl 38 
                 ALQ++dk+gv tP nW pGd+v++pP+++ eda+k++ 
  EEA21907.1 169 ALQTTDKKGVTTPINWLPGDDVVIPPTVSTEDAEKKFG 206
                 9**********************************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (224 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       309  (0.0172346); expected 358.6 (0.02)
Passed bias filter:                      283  (0.0157845); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.44u 0.22s 00:00:00.66 Elapsed: 00:00:00.40
# Mc/sec: 1662.85
//
Query:       EEA21908.1  [L=569]
Description: MFS multidrug transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.2e-40  136.6  28.6    9.2e-40  136.6  28.6    2.0  2  MFS_1     Major Facilitator Superfamily
    2.8e-06   26.5   6.4    2.8e-06   26.5   6.4    2.4  2  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  136.6  28.6     1e-43   9.2e-40       4     353 .]     113     515 ..     109     515 .. 0.83
   2 !    9.9   2.6   3.4e-05       0.3     105     184 ..     483     561 ..     480     567 .. 0.87

  Alignments for each domain:
  == domain 1  score: 136.6 bits;  conditional E-value: 1e-43
       MFS_1   4 aaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfasslwlllvlrvlqGlgaga 101
                 +++l+a++++ ++pa +  l ++ ++s  +++l lt+++ g+++a ++l+++s+  Grr+v++++ +lf ++ ++++  a++l   lv+r++ G+g+++
  EEA21908.1 113 VTLLAAYSAGEYTPASS-QLLSEWHVSQVAYNLGLTTFTTGFGIAPMILAPFSEINGRRPVFIASGILFTACiFACGG-ANNLAGTLVARFFKGIGGST 209
                 45666666666999999.78899*************************************************555555.355559************** PP

       MFS_1 102 lfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee............ 188
                 + ++++ +i+d+++ e+r+  ++l+++++ +G+ lgpl++g +++   Wr+v++ ++ vs+ ++++++++l e++ +   +++++ +            
  EEA21908.1 210 YSTMVGGVISDIYHAEDRNTPMALFAGAALFGTGLGPLVAGNIVARTTWRWVYWSHGMVSAGFVIFMYFFLKETRGSILLSRKARALnkwydsleeagy 308
                 ***************************************************************999888887777777777776666999999999999 PP

       MFS_1 189 ........................kgtgpaplvp........awkallkdpvlw.illialllfffgfsglltllplylqevlgls.....glllagll 249
                                         +  +++++v+        ++ +l++ pv++ + l+++++++ ++++ l+ +pl +q+ +g++         + ++
  EEA21908.1 309 ygmlmpsedlperrivrrirwkvkADEERQSIVQmislscyrPFHLLFTEPVVFfFSLWVAFSWA-VLYLQLSSVPLVMQTNHGFTvaqssD---VFAA 403
                 999999999999999999999998555555555566699999*********99767777777776.9999****************886533...3333 PP

       MFS_1 250 lallalvgailallagrlsdrlgr.....rrrlllallllllaalglallavtssavllll.vlvliGf.glgfv...fpsllalasdlappeeagtas 338
                 ++++++++  l++   +++ r+g+     + rl++a++  +l+ +gl+++++ts +++ ++ + + +G+ ++g++    + +++la+ ++  ++a +a+
  EEA21908.1 404 ISVGGILATLLSIYQEKIAIRFGKmsntpEGRLYFACIESVLMPVGLFWFGWTSFSSVPWIvPTIAVGCaTMGIFsvyLAVFNYLADTYH--RYASSAI 500
                 7777777777766666666666666666699**********************5555555524444666666665554666666666666..9****** PP

       MFS_1 339 glfntagslggalgp 353
                 ++ + +++l g ++p
  EEA21908.1 501 AAQSCCRNLLGGVFP 515
                 ********8888776 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 3.4e-05
       MFS_1 105 agaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrksp 184
                 a+  ++ad +++   ++ai+  s + +l   + pl+  ++  +lg++a+  +l+++++l+ ++ ++l++  p+ r+r++ 
  EEA21908.1 483 AVFNYLADTYHR-YASSAIAAQSCCRNLLGGVFPLVTNAMFNNLGFPAASSLLGGIGALLTIVPWVLVFYGPRIRARSKF 561
                 678899999999.***********************************************99877777777766666654 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.5   6.4   3.1e-10   2.8e-06      43     195 ..     120     284 ..      87     305 .. 0.77
   2 ?   -3.0   2.4      0.27   2.4e+03     382     382 ..     492     492 ..     457     550 .. 0.51

  Alignments for each domain:
  == domain 1  score: 26.5 bits;  conditional E-value: 3.1e-10
                 H....................HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHH CS
    Sugar_tr  43 e.................ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvP 124
                 +                 s+v + l +  f  G  i  +++ +++++ GR+++++++++lf ++++ ++ a+   ++   +v+R++ Gig  + s++v 
  EEA21908.1 120 SageytpassqllsewhvSQVAYNLGLTTFTTGFGIAPMILAPFSEINGRRPVFIASGILFTACIFACGGAN---NLAGTLVARFFKGIGGSTYSTMVG 215
                 044555555556666666777777888888888889999999999999**************9999999999...9999999********99******* PP

                 HHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCC.HHHHHHHHHHGGGS---H CS
    Sugar_tr 125 myisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglq.lvpallllilllflPESP 195
                   is i +++ R + + l+  a  fG  ++  +     ++ ++++wr+  ++  +v+a +++++ +fl E+ 
  EEA21908.1 216 GVISDIYHAEDRNTPMALFAGAALFGTGLGPLVA---GNIVARTTWRWVYWSHgMVSAGFVIFMYFFLKETR 284
                 ************9999999888877777776554...45555567999999862677788888889999985 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.27
                 T CS
    Sugar_tr 382 s 382
                  
  EEA21908.1 492 Y 492
                 1 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (569 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       532  (0.0296726); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.30s 00:00:00.89 Elapsed: 00:00:00.46
# Mc/sec: 3730.65
//
Query:       EEA21909.1  [L=513]
Description: AT DNA binding protein (Thy28), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.6e-43  146.4   0.1    1.4e-42  145.1   0.1    1.7  1  EVE       EVE domain
  ------ inclusion threshold ------
        3.1    6.3   4.8        5.1    5.6   4.8    1.3  1  DUF3138   Protein of unknown function (DUF3138)


Domain annotation for each model (and alignments):
>> EVE  EVE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.1   0.1   1.6e-46   1.4e-42       1     144 [.     217     369 ..     217     370 .. 0.95

  Alignments for each domain:
  == domain 1  score: 145.1 bits;  conditional E-value: 1.6e-46
                 -EEEEEEBHHT.........SHHHHH.CHHHCEEE-EE-GHHHHHHHCC--TT-EEEEEETSSSS-EEEEEEEEECEEEE-GGGG-TTSTT--TTTBTT CS
         EVE   1 ayWllksepde.........fsiddl.krkkeegWdgvrnyqarnllramkkGDlvlfYhsgeklqaivgiaeVvseaypdetqfdpkskyydpkskke 89 
                 +yWl+k+ep++         fsiddl ++++ e+Wd      arn++ramk+GD+++fYhs++k ++ivg +e+v+e+  de++fdp ++yyd+ks++e
  EEA21909.1 217 SYWLMKAEPESrivkgvdvkFSIDDLrATREPEPWD------ARNNMRAMKQGDYAFFYHSSCKVPGIVGQMEIVKEHSVDESAFDPAHPYYDEKSSRE 309
                 5*********99999***********9999*****5......7779***************************************************** PP

                 S-.-EEEEEEEEEEEEEEEEHHHHTT....HGTCTTSHHHHCCT-SEEEE-HHHHHHHHH CS
         EVE  90 kp.wlrvdvkpvkklkrplslkelka....epelegmkllrkgrlsvrpvteedwelile 144
                 +p w +v+v++ +k+++ l+l++lk+     + le+m+ lr++r sv++v++++w++i+ 
  EEA21909.1 310 NPkWECVHVEFRRKFDQTLTLETLKSygfpGQPLENMQTLRQSRVSVSRVSPQEWNFIMG 369
                 **************************6555358*************************86 PP

>> DUF3138  Protein of unknown function (DUF3138)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   4.8   0.00056       5.1      52      91 ..     373     411 ..     343     431 .. 0.76

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.00056
     DUF3138  52 kaaaGgkissqkaaaaaaaaaeaaaalteddvaqlkeqia 91 
                 k  aG+k +s kaaa  a+aa   aa t+++ +++k+  a
  EEA21909.1 373 KQEAGAKKASAKAAAKEAKAAAKEAAATDNADTEMKDA-A 411
                 4789************99999999999********985.3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (513 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1518  (0.0846673); expected 358.6 (0.02)
Passed bias filter:                      518  (0.0288917); expected 358.6 (0.02)
Passed Vit filter:                        99  (0.00552178); expected 17.9 (0.001)
Passed Fwd filter:                        35  (0.00195214); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.92u 0.32s 00:00:01.24 Elapsed: 00:00:00.48
# Mc/sec: 3226.83
//
Query:       EEA21910.1  [L=278]
Description: DUF858 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.5e-68  229.8   0.0    2.2e-55  187.6   0.0    2.6  2  Methyltransf_PK  AdoMet dependent proline di-methyltransferas
    3.5e-09   36.7   0.0    7.2e-09   35.7   0.0    1.5  1  Methyltransf_23  Methyltransferase domain
    0.00017   22.3   0.0     0.0016   19.1   0.0    2.2  1  Methyltransf_25  Methyltransferase domain
    0.00032   21.3   0.0     0.0019   18.8   0.0    2.1  1  Methyltransf_11  Methyltransferase domain
     0.0014   19.4   0.2      0.012   16.3   0.0    2.2  2  Methyltransf_12  Methyltransferase domain
  ------ inclusion threshold ------
      0.049   14.2   1.7        9.5    6.8   1.1    2.5  2  Secretin_N_2     Secretin N-terminal domain
      0.099   12.9   0.0        0.2   11.9   0.0    1.4  1  DUF3069          Protein of unknown function (DUF3069)
        0.2   10.4   0.0       0.28    9.9   0.0    1.3  1  UDPGT            UDP-glucoronosyl and UDP-glucosyl transferas


Domain annotation for each model (and alignments):
>> Methyltransf_PK  AdoMet dependent proline di-methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.3   0.0   2.2e-13   4.8e-10       4      50 ..      11      57 ..       8      70 .. 0.84
   2 !  187.6   0.0   9.7e-59   2.2e-55      51     218 .]      85     273 ..      71     273 .. 0.89

  Alignments for each domain:
  == domain 1  score: 39.3 bits;  conditional E-value: 2.2e-13
  Methyltransf_PK  4 evyekaiaYWesveadvdGvLGGygavskiDvkgsrkflkklkkesl 50
                     + +  +++YW+s+ ++v+G+LGG+ +vs+iD+ gs +fl+k+++  +
       EEA21910.1 11 INHATSLEYWNSIPPTVNGMLGGFPQVSRIDLRGSASFLAKIRRLIQ 57
                     5667789*********************************9976544 PP

  == domain 2  score: 187.6 bits;  conditional E-value: 9.7e-59
  Methyltransf_PK  51 pgkrevkvaldcGaGiGrvtknlLlkllskvDlvepvekflekakee.lae.................ekkkvgkvyvvglqeftPeegrYdli 126
                       + ++ k+ +dcGaGiGr+t+ +L ++ + vD+vepv+kf e +++  l +                 e+  + ++y++gl+++ Pe ++Ydli
       EEA21910.1  85 RKSKKLKRGVDCGAGIGRITEGFLRNVCETVDVVEPVAKFAEVIQNGpLIRrkkttattttdgttegeEEGVIENIYITGLETWLPE-HKYDLI 177
                      456788999*******************************9987753222234555678999999987777899************7.69**** PP

  Methyltransf_PK 127 WiqWcvghLtDedlvaflkrckkalkpnGlivvkenvak..eekdelDkeDssvtrseaklkklfkkagLklvaeelqkglPk..elypvkmya 216
                      W+qWcvghLtD++l  +l+r+++al pnG+iv+ken+++   + d++D+ Dssvtr++++++++fk+agL+l+++e+q g+P+   l+pv++ya
       EEA21910.1 178 WNQWCVGHLTDAQLTTYLQRAANALTPNGIIVLKENNSTdpAGRDIYDEIDSSVTRTDETFRRIFKEAGLNLIKAEEQLGFPRhlGLLPVRSYA 271
                      ************************************98633699***************************************6668******* PP

  Methyltransf_PK 217 Lk 218
                      L+
       EEA21910.1 272 LR 273
                      96 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.7   0.0   3.2e-12   7.2e-09      19     163 ..      86     250 ..      71     252 .. 0.76

  Alignments for each domain:
  == domain 1  score: 35.7 bits;  conditional E-value: 3.2e-12
  Methyltransf_23  19 klraggrvLdiGcGtGillevlrengf.svtgvDlspeaveiae..........kakkaqkdqfdeqeaae.................pqgkfd 84 
                      k ++ +r +d G+G G+ +e + +n++ +v++v++  +  e ++          +a +  +  +    + e                 p+ k+d
       EEA21910.1  86 KSKKLKRGVDCGAGIGRITEGFLRNVCeTVDVVEPVAKFAEVIQngplirrkktTATTTTDGTT----EGEeegvieniyitgletwlPEHKYD 175
                      467889*********************8999****98888888787777654432222222222....22222344445555554555666*** PP

  Methyltransf_23  85 lIvlrevlehvpd..ppellrqiatllkpgGylllseplaslkedrl.lldwlylvpagrhisffsarslkelleeaGlevv 163
                      lI +  + +h+ d  ++ +l+++a+ l p+G ++l e ++ +++ r+ ++++   v++       + ++++++++eaGl+++
       EEA21910.1 176 LIWNQWCVGHLTDaqLTTYLQRAANALTPNGIIVLKENNSTDPAGRDiYDEIDSSVTR-------TDETFRRIFKEAGLNLI 250
                      ************8889***********************9998887746666666666.......55999999999999987 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   7.2e-07    0.0016       2      97 .]      94     206 ..      94     206 .. 0.74

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 7.2e-07
                      EEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHH.............HHHHHTTT...........TEEEEESBCCGBSSSTTTEEEEEEE CS
  Methyltransf_25   2 LdlGcGtGrltlalakrlgkakvtgvDiseemleaar.............eraeeegl...........nvefvqgdaedlpfedgsfDlvvss 71 
                      +d+G+G Gr+t+ +++++  ++v  v++ +++ e ++             +                   +e +     +  ++++++Dl++ +
       EEA21910.1  94 VDCGAGIGRITEGFLRNV-CETVDVVEPVAKFAEVIQngplirrkkttatT------TtdgttegeeegVIENIYITGLETWLPEHKYDLIWNQ 180
                      599************998.799*******9999998888777664333220......12332333222233333333344457999*******9 PP

                      STGGGSSHHHHHHHHHHHHHHEEEEE CS
  Methyltransf_25  72 galhhlsdedlekalkeiarvLkpgG 97 
                       ++ hl+d++l ++l+++a++L+p+G
       EEA21910.1 181 WCVGHLTDAQLTTYLQRAANALTPNG 206
                      99**********************99 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.0   8.5e-07    0.0019       2      96 .]      95     210 ..      94     210 .. 0.67

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 8.5e-07
                      EET-TTSHHHHHHHHTT.SEEEEEES-HHHHHHH......HHHCCHHT-............EEEETTEECCCTSS-TT-EEEEEEES-CCC-.. CS
  Methyltransf_11   2 dvGcGtGrlaealakrg.arvvgvDlskemlkla......kekaseegl............kvefvvadaeklpfednsfDlvvssevlhhv.. 74 
                      d+G+G Gr++e + +++ ++v  v++ +++ ++       ++k+ ++               +e +  +  ++ ++++++Dl++ ++++ h+  
       EEA21910.1  95 DCGAGIGRITEGFLRNVcETVDVVEPVAKFAEVIqngpliRRKKTTATTttdgttegeeegVIENIYITGLETWLPEHKYDLIWNQWCVGHLtd 188
                      899999999999997775666677777777755544444422222222233444444333322223333334579*****************98 PP

                      CCHHHHHHHHHHHEEEEEEEEE CS
  Methyltransf_11  75 edpekalkeiaRvLkpgGllvi 96 
                      +++  +l+ +a  L p+G++v+
       EEA21910.1 189 AQLTTYLQRAANALTPNGIIVL 210
                      8999***************985 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.3      0.47   1.1e+03      39      59 ..      61      81 ..      45      90 .. 0.60
   2 !   16.3   0.0   5.5e-06     0.012       2      99 .]      95     208 ..      94     208 .. 0.77

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.47
  Methyltransf_12 39 klakrennnnnnvelealdll 59
                       +++e+ nn+n+++e++d++
       EEA21910.1 61 SSQEEEESNNSNNNNEEEDVA 81
                     334444555555555555554 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 5.5e-06
  Methyltransf_12   2 eiGcGtGsllralleklpdieyt.gvDispsaiedakeklakrennnnnnvelealdlldldgg................ssfDlvvasnvlhh 78 
                      + G+G G++++ +l++   +e + +v++ +++     +    +++++++  + ++   + +++g                +++Dl++   ++ h
       EEA21910.1  95 DCGAGIGRITEGFLRN--VCETVdVVEPVAKFA-EVIQNGPLIRRKKTTATTTTDGTTEGEEEGvieniyitgletwlpeHKYDLIWNQWCVGH 185
                      7899999999999999..666666999999999.44444455555555555555555444444589*********************9966666 PP

  Methyltransf_12  79 l..kdirevldnirklLkpgGrl 99 
                      l  +++  +l++++++L+p+G++
       EEA21910.1 186 LtdAQLTTYLQRAANALTPNGII 208
                      6599999**************85 PP

>> Secretin_N_2  Secretin N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.0     0.011        25      57      82 ..       7      32 ..       1      42 [. 0.81
   2 ?    6.8   1.1    0.0042       9.5      25      48 ..      60      83 ..      50     105 .. 0.52

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.011
  Secretin_N_2 57 sgtkietesesdfwgeLqkalesmlg 82
                    ++i+  ++ ++w+ +  ++++mlg
    EEA21910.1  7 PDSNINHATSLEYWNSIPPTVNGMLG 32
                  5689999******************8 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.0042
  Secretin_N_2 25 svsssgsssssssssssssgssss 48
                  + s+++++s++s++++++++ +++
    EEA21910.1 60 QSSQEEEESNNSNNNNEEEDVAGQ 83
                  333333333333333321222211 PP

>> DUF3069  Protein of unknown function (DUF3069)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   8.9e-05       0.2      24     103 ..      14      91 ..       6      94 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 8.9e-05
                 -HHHHHHHHS-HHHHTSS-H.HHHHHHHHHHHHHHHHHH--..-HHHHHHTTTTS-HHHHHHHHHHHHHTHHHHHHHHHH CS
     DUF3069  24 ekvreaWdalPaSAqnlldnfeqFhalvianaflqlsrvaeleeiseqedsdeeekeeernqlldrvlenslKelvkklK 103
                 ++  e W+++P   + +l  f q   + +  + + l  + +l +i+++ +++ee ++ ++n+  + v+ +s K   kklK
  EEA21910.1  14 ATSLEYWNSIPPTVNGMLGGFPQVSRIDLRGSASFLAKIRRLIQIEQSSQEEEESNNSNNNNEEEDVAGQSRKS--KKLK 91 
                 567789***********************999999**************************9999999999875..6666 PP

>> UDPGT  UDP-glucoronosyl and UDP-glucosyl transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0   0.00013      0.28     187     243 ..     205     262 ..     167     270 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00013
       UDPGT 187 NmlinLlvdflfqllkek.ydelasevlgrpvtlaellskaevwllrsyfdlefPrpl 243
                 N +i+L ++  ++   ++ yde+ s v +++ t+  ++++a + l++   +l+fPr+l
  EEA21910.1 205 NGIIVLKENNSTDPAGRDiYDEIDSSVTRTDETFRRIFKEAGLNLIKAEEQLGFPRHL 262
                 5578899999999999999*************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (278 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1091  (0.0608511); expected 358.6 (0.02)
Passed bias filter:                      721  (0.0402142); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.56u 0.29s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 1880.97
//
Query:       EEA21911.1  [L=520]
Description: F-box domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
  ------ inclusion threshold ------
       0.17   11.8   3.6        1.3    8.9   3.6    2.5  1  F-box-like  F-box-like


Domain annotation for each model (and alignments):
>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   3.6   7.4e-05       1.3       6      47 ..      15      89 ..      10      90 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 7.4e-05
  F-box-like  6 dEiLlqIF...................................syLppsdLlrlalVCrrWrrvaldtplLWrrlvl 47
                dE+L+ I+                                   s+ + sdL r +lVC r+ r+a  tp   rr +l
  EEA21911.1 15 DELLSLILsfliadtefpdgreiihdyafppynskrngtnavaSRGERSDLDRYRLVCTRFMRIA--TPWKFRRFTL 89
                67888888666666666666666666666666655555555544336778***************..9888888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (520 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       972  (0.0542138); expected 358.6 (0.02)
Passed bias filter:                      587  (0.0327403); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.42
# Mc/sec: 3687.92
//
Query:       EEA21912.1  [L=131]
Description: hypothetical protein PMAA_057010 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (131 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       326  (0.0181828); expected 358.6 (0.02)
Passed bias filter:                      261  (0.0145574); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.27s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 945.06
//
Query:       EEA21913.1  [L=391]
Description: pantetheine-phosphate adenylyltransferase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.5e-08   33.4   0.0    3.6e-07   30.5   0.0    2.3  2  CTP_transf_like  Cytidylyltransferase-like
  ------ inclusion threshold ------
      0.042   13.8   0.1      0.073   13.0   0.1    1.4  1  FAD_syn          FAD synthetase


Domain annotation for each model (and alignments):
>> CTP_transf_like  Cytidylyltransferase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0      0.15   1.4e+03      86     119 ..     105     147 ..      67     181 .. 0.68
   2 !   30.5   0.0   4.1e-11   3.6e-07       1     143 []     196     382 ..     196     382 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.15
                      EEEEEHHHHHHHHCHHHHHH.HHHHHHHEEEEEE........H CS
  CTP_transf_like  86 ylvigadvledfsewkelee.ilgnvklvvvsrp........e 119
                      ++ ++   +e++++wk+++  i++ ++l+  +rp         
       EEA21913.1 105 VFFVDNTEYEQAENWKRIQGpIIDFRTLATSQRPwdhvyvpsT 147
                      4555666677788999888557888888888888555555540 PP

  == domain 2  score: 30.5 bits;  conditional E-value: 4.1e-11
                      EEEE--TT--HHHHHHHHHHHHHSSES.....EEEEEESSTHCSST-..SCSSTHHHHHHHHHHH.TTCTTEEEEEEESEHH............ CS
  CTP_transf_like   1 lagGtFDpiHlGHlrlleqakklleed.....livgvpsdeppkkkk..kplasaeeRlemlela.kevdevisvdpweltr............ 74 
                      ++gGtFD +HlGH  ll   +  l+ +     l vg++ d+   +kk  + l s eeR++ +  + +   +   ++p e+              
       EEA21913.1 196 IVGGTFDHLHLGHKLLLTATALTLDVTrdkkvLAVGITGDQMLVNKKfaEYLESWEERMQGTASFlRAIVD---FNPPETSSadltrteqpgpn 286
                      589*********************99999************99999888************9999655555...33333333335558889999 PP

                      ........................HHHHHTTTTEEEEEEEHHHHHHHHCHHHHHHHHHHHHHEEEEEE.....HTTCEEEEEEECCTTTCSHHH CS
  CTP_transf_like  75 ........................evlkklkpdklylvigadvledfsewkeleeilgnvklvvvsrp.....ekqanvllkaekrtngiSstk 139
                                               ++++ +    +l+++a++ +  +  +  +   g+  l v+++      e q++  + a+  +++iSst+
       EEA21913.1 287 gkqvsfqvapdttvrlvqiddpfgPTITEEQFS--ALIVSAETRSGGQAVNTERNKKGWASLEVFEVGvlqagEAQEVADTSASSFESKISSTD 378
                      999999999999999998888888777777777..888888888887777777777777777777777999999999999************** PP

                      HHHH CS
  CTP_transf_like 140 irer 143
                      ir+r
       EEA21913.1 379 IRQR 382
                      **97 PP

>> FAD_syn  FAD synthetase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.1   8.1e-06     0.073       4      29 ..     190     215 ..     187     249 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 8.1e-06
     FAD_syn   4 edegavvtlGnFDGvHlGHqallkka 29 
                 +++ av++ G FD +HlGH+ ll+ +
  EEA21913.1 190 TSHAAVIVGGTFDHLHLGHKLLLTAT 215
                 5677899999**********999764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (391 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       431  (0.0240393); expected 358.6 (0.02)
Passed bias filter:                      359  (0.0200234); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.41
# Mc/sec: 2845.98
//
Query:       EEA21914.1  [L=622]
Description: WD repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-13   51.0  10.8    4.6e-06   27.3   0.3    5.6  5  WD40      WD domain, G-beta repeat


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.0     0.025   4.6e+02      10      37 ..     283     315 ..     275     316 .. 0.68
   2 !   11.4   0.3   2.7e-05      0.48       9      38 .]     354     385 ..     347     385 .. 0.80
   3 !   12.3   0.0   1.4e-05      0.26       7      38 .]     395     428 ..     390     428 .. 0.75
   4 ?   -0.2   0.0      0.12   2.1e+03       8      32 ..     456     486 ..     449     491 .. 0.66
   5 !   27.3   0.3   2.5e-10   4.6e-06       2      38 .]     499     537 ..     498     537 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.025
                 SSS.EEEEEEETTSSE.....EEEEETTSEEEEE CS
        WD40  10 Hss.vtslafspdgaw.....lasGsdDgtvriW 37 
                 Hs  vt + + p ++      l++ s   ++r+W
  EEA21914.1 283 HSYpVTRILWEPPSSQkqstdLLATS-GDHLRLW 315
                 62248888766666667777755567.8888888 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 2.7e-05
                 SS.SSEEEEEEETTSSE.......EEEEETTSEEEEEE CS
        WD40   9 GH.ssvtslafspdgaw.......lasGsdDgtvriWd 38 
                  H  ++tsl      +w       ++++s D t+ iWd
  EEA21914.1 354 EHtAPITSL------DWnilspslIITSSIDTTCTIWD 385
                 58778****......7777777766799*********9 PP

  == domain 3  score: 12.3 bits;  conditional E-value: 1.4e-05
                 EESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS
        WD40   7 ltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 
                 l +H + v++++f+ ++   ++s++ Dg+vr++d
  EEA21914.1 395 LIAHdKEVYDVRFCANSVDvFVSCGADGSVRMFD 428
                 67998889999766666663468888******98 PP

  == domain 4  score: -0.2 bits;  conditional E-value: 0.12
                 ESS..SS...EEEEEEETTSSEEEEE.ETTS CS
        WD40   8 tGH..ss...vtslafspdgawlasG.sdDg 32 
                  GH  s+      +a+sp+ a l++  s D 
  EEA21914.1 456 PGHsiSWpppLLRIATSPHDAHLLATfSQDS 486
                 4774433666568898999998876556554 PP

  == domain 5  score: 27.3 bits;  conditional E-value: 2.5e-10
                 EEEEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 
                 q l +l+GH  sv+++ +sp+ +  lasG+dD+ v +Wd
  EEA21914.1 499 QALVELRGHsASVNCIEWSPSRRGtLASGGDDCCVLVWD 537
                 667789***777****9999999999************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (622 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       382  (0.0213063); expected 358.6 (0.02)
Passed bias filter:                      225  (0.0125495); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.50
# Mc/sec: 3725.14
//
Query:       EEA21915.1  [L=533]
Description: acyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.8e-35  122.7  36.2    2.4e-35  122.2  36.2    1.2  1  Acyl_transf_3  Acyltransferase family


Domain annotation for each model (and alignments):
>> Acyl_transf_3  Acyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  122.2  36.2   1.4e-39   2.4e-35       2     340 .]      92     508 ..      91     508 .. 0.93

  Alignments for each domain:
  == domain 1  score: 122.2 bits;  conditional E-value: 1.4e-39
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxxxxxx..........xxxxxxxxxxxxxxxxx RF
  Acyl_transf_3   2 aylDllRgiAillVvflHaliayspdagrgspiqasqssqi........aflggfgvplFFllSGffla..........amlyrrrglsklikrRi 79 
                    a+lD+lRg+A+llV+ +H++  y + ++ g++   +++  +        +f+g+++v +FF++SG++l+          a       ls++ +rR 
     EEA21915.1  92 AALDGLRGWACLLVFNFHFFFTYTWHTHIGWGFNKQYF-GLhqlpffhmIFSGHIMVAIFFVISGYVLSyrplktirsgAFEQTFAVLSSATFRRG 186
                    78*************************99997766555.44599*********************************99999999*********** PP

                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..........................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Acyl_transf_3  80 lrlliplliwllliillialvaghiqanasanvtlfdet..........................kglmfllfefpatghlWfLwalfvlylllpl 149
                    lrl+ip +++l+++++ + l+ +  + ++     +   t                           ++ + l  +++++hlW+++++f  +++l++
     EEA21915.1 187 LRLYIPSIVGLFCVFVAVRLGLYNYSRWVVDHSRTITGTneqhpiilrstyiqlwdwynticrlmNFWDWGLYYNNYNPHLWTIPVEFRSSMVLFV 282
                    ***************************999999999888*************************9999999************************* PP

                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......................... RF
  Acyl_transf_3 150 llrllrkvrkshlllllilllllslvfirhelfgpatsvgllplpsvlallfflfGalladaddrdrnlsr......................... 220
                     + ++ ++r +++l+l +++l + + ++r+                   ++ fl+G++la  d + ++++                          
     EEA21915.1 283 TILAVSRFRTKVRLILEAMTLWFCVRWGRWD------------------VVLFLSGLILAEIDLENGIWNNntattsncesataplsdleklvgtt 360
                    *******************************..................799******************************************** PP

                    ...xxxxxxxxxxxxxxxxxxxxxxxxxx...........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxx RF
  Acyl_transf_3 221 ...glkislllsllllalillalfgqtdg...........gglvasvliqsaslllvslgimllllllfalpsrsafk...llrylgkiSygiYli 299
                        l++++  +++  ++il ++ g++ +           +  + + ++  ++++  +lg+ l++ + + ++ +++++   l +ylg+iSy++Y++
     EEA21915.1 361 svqSLLRRRQNAIWIGIFILGLYMGSSPNigglytpgyvwLAHITPKTYPEPHRFPQTLGAVLIVASINNSKTIQKIFvnpLSQYLGQISYAFYIV 456
                    **966666677777777777777777766888888889999999**************************************************** PP

                    xxxxxxxxxxxxxxxxxx...........xxxxxxxxxxxxxxxxxxxxxxx RF
  Acyl_transf_3 300 Hlpllmllqkllrdwgln...........lgevlllvlllvvsvivsvvlli 340
                    H+p+l+ l+++l +++ +           +g ++ + ++l+++++++ ++++
     EEA21915.1 457 HGPILHGLGYTLMHNIWQitgretafqflFGAAIGWSICLPIALWLADIFWR 508
                    ***************5557788888889999999999999999999999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (533 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       633  (0.0353059); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.25s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 3619.29
//
Query:       EEA21916.1  [L=790]
Description: mRNA capping nucleoside-triphosphatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.1e-62  210.7   0.0    3.3e-62  210.1   0.0    1.3  1  mRNA_triPase  mRNA capping enzyme, beta chain


Domain annotation for each model (and alignments):
>> mRNA_triPase  mRNA capping enzyme, beta chain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  210.1   0.0   1.8e-66   3.3e-62       2     219 .]     501     748 ..     500     748 .. 0.94

  Alignments for each domain:
  == domain 1  score: 210.1 bits;  conditional E-value: 1.8e-66
                   -HHHHHHHHHHHHHHHH...........CTCCGGCCEEEEEEEEEEEETTTSSB---SBSS-EEE-TT...CTEEEEE-B-HHHHHHHHHHHHHHHH CS
  mRNA_triPase   2 deitksvsdwiiaaldn...........iksekrsqiEiEaklGlivdkstkeRlklpvsteaivenn...adskfesgvdedqfkelnnfLnelsr 84 
                   +eitk+v+d++++++++           +++ + +++EiEaklG i+dk+++ Rl+lpv++e+i++ +   +++ fes+++ +q++++nnfLne+ +
    EEA21916.1 501 EEITKTVCDFLFKEVVCrpdlaagaagaAATGSGAMLEIEAKLGRIMDKDRQGRLRLPVMSECILQTEnsgYRTAFESSMSLAQHQAMNNFLNEAVK 597
                   79*************************9555556*******************************9888899**********************765 PP

                   ...HTTCCCTTTEEEEEEEEEEEEEE-S............-SSS--EEEEEEETTT--EEEEEEEEEEEEEEEE-TTSSSEEEEEEEEEEE-SSS.. CS
  mRNA_triPase  85 r.neeenskrekvslkeskevDkfYelk............kkeekskirvskdsenqevlkkieKeriadlniylPnsklDyriSinlElpvses.. 166
                     + ++  +r+++s+ +++e+D+fYe++            ++++k k+rv++d++++e+l+ki K+r+adl++y+P++++D+riS+nlE++++ +  
    EEA21916.1 598 AsMPQAGLNRIPLSYAHKRERDTFYEVPpselppliqnylNPRHKPKVRVTTDQKTGEILAKIIKCRLADLDVYSPRTNVDWRISVNLEMNYDRDvh 694
                   4589999**************************************************************************************9998 PP

                   ...HHHCTTS--SEEEEEEEEEEEECCGTEEEEEEEESSS---S--EEEEEEEEEE CS
  mRNA_triPase 167 ...kaklskktpvseRlkeRlSyihkksgiqfDLtkvektektkkteekyElEiEi 219
                       a   +++p  eR k+R+Sy+h +  +q+DLt+v +   + k++ ++ElE+Ei
    EEA21916.1 695 nfpIAGGGSQKPGGERIKDRMSYRHLA--YQIDLTQVGTADSAIKKDFEHELEVEI 748
                   77767778999****************..********555889999*********8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (790 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       680  (0.0379274); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.80u 0.34s 00:00:01.14 Elapsed: 00:00:00.54
# Mc/sec: 4406.76
//
Query:       EEA21917.1  [L=1021]
Description: transcription initiation protein spt5 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.5e-24   84.5   0.0    6.4e-24   83.7   0.0    1.5  1  Spt5-NGN     Early transcription elongation factor of RNA pol
    3.6e-18   65.9  54.5    1.2e-14   54.6  10.3    4.0  3  CTD          Spt5 C-terminal nonapeptide repeat binding Spt4
    1.4e-17   64.5   8.8    1.4e-17   64.5   8.8    4.0  3  Spt5_N       Spt5 transcription elongation factor, acidic N-t
    4.4e-11   42.3  13.0    0.00015   21.6   0.0    5.0  4  KOW          KOW motif
  ------ inclusion threshold ------
      0.019   15.2   1.5        1.6    9.0   0.1    3.3  3  DUF3912      Protein of unknown function (DUF3912)
       0.31   10.1  33.1       0.64    9.1  33.1    1.5  1  DUF2457      Protein of unknown function (DUF2457)
        1.2    8.5  29.5        2.3    7.5  29.5    1.4  1  SDA1         SDA1
        2.6    6.0  40.4        3.7    5.5  40.4    1.1  1  DNA_pol_phi  DNA polymerase phi


Domain annotation for each model (and alignments):
>> Spt5-NGN  Early transcription elongation factor of RNA pol II, NGN section
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.7   0.0   2.9e-27   6.4e-24       1      84 []     209     296 ..     209     296 .. 0.97

  Alignments for each domain:
  == domain 1  score: 83.7 bits;  conditional E-value: 2.9e-27
    Spt5-NGN   1 siwavkctagqErevalslmkkilelakken..leIkSvfapde.lkGyiyvEAdrkaaveralegipnvrgvv.qglvpikEvedll 84 
                 siw v+c++g+Er+v+l+++k+i+++  +++  l+I+S+f++ + ++Gy+y+EA+r+a v++al+g+ +v++ + + lvp+kE++dll
  EEA21917.1 209 SIWGVRCKPGKERDVVLNIQKRIEQRPPGTRhgLKIISAFERGKtMTGYVYIEARRQAEVMEALDGLLDVYPKTkMVLVPVKEMPDLL 296
                 69************************9999999*********998****************************98899********97 PP

>> CTD  Spt5 C-terminal nonapeptide repeat binding Spt4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8   2.5   4.5e-08    0.0001      35      71 .]     805     838 ..     797     838 .. 0.79
   2 !   54.6  10.3   5.3e-18   1.2e-14       1      52 [.     830     884 ..     830     892 .. 0.91
   3 !    7.0  29.7     0.004       8.9       1      57 [.     895     963 ..     895    1016 .. 0.63

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 4.5e-08
         CTD  35 tPawnagskTPahgaagsrTPayktawdgsrTpaygg 71 
                  P+w ags+TP  +  +srTPa++++   srTpa+gg
  EEA21917.1 805 QPNW-AGSRTPMAS-LDSRTPAWGGSL-SSRTPAWGG 838
                 5888.788888888.888888888887.888888875 PP

  == domain 2  score: 54.6 bits;  conditional E-value: 5.3e-18
         CTD   1 gsrTPawns..aggsrTPawgadgsrTpaygga..gsrtPawnagskTPahgaags 52 
                 +srTPaw++  a+gsrTPaw+adgsrT aygga  g+rtPawn+g++TP+++++g 
  EEA21917.1 830 SSRTPAWGGsaASGSRTPAWKADGSRT-AYGGAmgGGRTPAWNSGARTPYDSGSGG 884
                 69******999***************7.****999****************96655 PP

  == domain 3  score: 7.0 bits;  conditional E-value: 0.004
         CTD   1 gsrTPawnsaggsrTPawgadgsrTpayggagsrtPawnagskTPahg.................aagsrTPay 57 
                 gsrTPaw++a+gsrTPaw a++++ p+  +   +t  +  ++ TP  +                    ++TP +
  EEA21917.1 895 GSRTPAWGAATGSRTPAWTANSNSAPSAAA---NTGRY--DAPTPGGDysaptpgayptaptpgaSGTASTPRW 963
                 79****************998888744443...44444..4444444411111111133333322244455555 PP

>> Spt5_N  Spt5 transcription elongation factor, acidic N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?  -10.5  13.0         8   1.8e+04       5      13 ..      41      49 ..       8      53 .. 0.52
   2 ?  -21.2  45.3         8   1.8e+04       5      46 ..      41      93 ..      39     106 .. 0.39
   3 !   64.5   8.8   6.1e-21   1.4e-17       1      99 []     109     203 ..     109     203 .. 0.83

  Alignments for each domain:
  == domain 1  score: -10.5 bits;  conditional E-value: 8
                XXXXXXXXX CS
      Spt5_N  5 eAeVdddee 13
                e+eVd+d e
  EEA21917.1 41 EVEVDEDAE 49
                455555532 PP

  == domain 2  score: -21.2 bits;  conditional E-value: 8
                XXXXXXXXXX............XXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXX CS
      Spt5_N  5 eAeVdddeee............eeeeeeveggeddfiaeeeaeeeeedserddr 46
                e+eVd+d e+            e+e +e+e +++++ +ee+++e+++d+++d+ 
  EEA21917.1 41 EVEVDEDAEDdnegaegegrgdEDEGDEDEAEDEED-EEEDEDEDDDDDDEDAV 93
                789999986645555555554322222222222221.11112222222222222 PP

  == domain 3  score: 64.5 bits;  conditional E-value: 6.1e-21
                 XXXXXXXXXXXX.XXXXXXXXXXXXXX.XXXXXXXXXXXXX....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..X-G CS
      Spt5_N   1 FiddeAeVddde.eeeeeeeeveggeddfiaeeeaeeeeed....serddrshreldrrrqaeededaeeiaealeeRYgrsskkayrgeaeessevpq 94 
                 Fi++eA Vddd+ e e+ee+++++   +    e ++++ ++    +e ddr+hr+ldr+r+ e+++dae++a+al+eRYgr  ++ + +++     vp+
  EEA21917.1 109 FIEEEAGVDDDDeEAEDEEDDMGDVFGA----EAHPDDLDAlplgAELDDRRHRQLDRQRELEAHMDAEKQAAALKERYGR--NRMAATDSVV---VPK 198
                 9**********94446677776666555....5677777777888899*******************************98..4444567777...*** PP

                 GGG-- CS
      Spt5_N  95 qlLLP 99 
                 +lLLP
  EEA21917.1 199 RLLLP 203
                 ****9 PP

>> KOW  KOW motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.6   0.0   6.7e-08   0.00015       1      31 [.     306     336 ..     306     338 .. 0.89
   2 ?   -1.6   0.1       1.3   2.9e+03       1      14 [.     467     480 ..     467     484 .. 0.66
   3 !   15.0   1.0   7.8e-06     0.017       1      29 [.     520     549 ..     520     552 .. 0.89
   4 !   10.6   0.5   0.00019      0.42       2      31 ..     732     761 ..     731     762 .. 0.92

  Alignments for each domain:
  == domain 1  score: 21.6 bits;  conditional E-value: 6.7e-08
                 TTSEEEESSSTTTTCEEEEEEEETTTTEEEE CS
         KOW   1 pGdhVkVvsGphkGktGkVvkvdqhkvrVfv 31 
                 pGd+V++ +G++ G+ +++++v+ +   V+v
  EEA21917.1 306 PGDWVRIKRGKYQGDLAQIEEVETNGLEVTV 336
                 8**********************99955554 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 1.3
                 TTSEEEESSSTTTT CS
         KOW   1 pGdhVkVvsGphkG 14 
                 pGd V+V  G   G
  EEA21917.1 467 PGDQVEVYKGEQQG 480
                 89***995555555 PP

  == domain 3  score: 15.0 bits;  conditional E-value: 7.8e-06
                 TTSEEEESSS.TTTTCEEEEEEEETTTTEE CS
         KOW   1 pGdhVkVvsG.phkGktGkVvkvdqhkvrV 29 
                 +GdhVkV++G ++ ++ G+Vv+v  + v++
  EEA21917.1 520 EGDHVKVIGGsRYQDELGMVVQVKGDSVTI 549
                 5*********88999*********999776 PP

  == domain 4  score: 10.6 bits;  conditional E-value: 0.00019
                 TSEEEESSSTTTTCEEEEEEEETTTTEEEE CS
         KOW   2 GdhVkVvsGphkGktGkVvkvdqhkvrVfv 31 
                 G++V ++ G +kG +G+V +  ++ vrV +
  EEA21917.1 732 GKTVGITKGSYKGLIGIVRETTEDLVRVEL 761
                 88999**********************986 PP

>> DUF3912  Protein of unknown function (DUF3912)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.0      0.38   8.4e+02       8      28 ..     308     328 ..     306     358 .. 0.80
   2 ?    2.2   0.1     0.098   2.2e+02      16      54 ..     531     571 ..     521     588 .. 0.74
   3 ?    9.0   0.1   0.00072       1.6       4      30 ..     729     754 ..     721     791 .. 0.75

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.38
     DUF3912   8 qkvyvkdGPyrnklGvvkkke 28 
                   v +k+G y++ l  +  +e
  EEA21917.1 308 DWVRIKRGKYQGDLAQIEEVE 328
                 56789*******998776643 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.098
     DUF3912  16 PyrnklGvvkkkeqedddhftvv..iddqdidvelkdill...v 54 
                  y++ lG+v +   ++ d  t+   +   +i+v  kd+ l    
  EEA21917.1 531 RYQDELGMVVQ---VKGDSVTILsdMSMEEITVFSKDLRLsteS 571
                 59*******99...777777777688888999999988765553 PP

  == domain 3  score: 9.0 bits;  conditional E-value: 0.00072
     DUF3912   4 dilGqkvyvkdGPyrnklGvvkkkeqe 30 
                 +++G++v + +G y++ +G+v+    e
  EEA21917.1 729 RLIGKTVGITKGSYKGLIGIVRE-TTE 754
                 679*******************9.333 PP

>> DUF2457  Protein of unknown function (DUF2457)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1  33.1   0.00029      0.64      41     125 ..      37     130 ..      34     202 .. 0.65

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00029
     DUF2457  41 kLgeeae..eEaeeeeeee......eddeedeeddddddddedddedddeedededddstved.lseeasdGyet..DnEaGFAdSdee.ddedddl 125
                 + g+e+e  e+ae+++e +      ++de de++++d++d+e+d+++   +d+d+d+d+ + +  ++++  G ++  ++EaG  d dee +de+dd+
  EEA21917.1  37 RRGREVEvdEDAEDDNEGAegegrgDEDEGDEDEAEDEEDEEEDEDE---DDDDDDEDAVSGRpKKRRRRGGVNAfiEEEAGVDDDDEEaEDEEDDM 130
                 55666642166666666556666554444444444444443333333...2222223333333356667777775448999*999995514555554 PP

>> SDA1  SDA1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5  29.5     0.001       2.3      89     181 ..      20     170 ..       4     201 .. 0.52

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.001
        SDA1  89 e.....eeeedsddeddeedwevesdddseedseggwidvesdeeeieesdesedeeeeeeeeeekeekeeeeeeee....................ee 162
                 +     +++e+    d  ++ eve d+d e+d+eg   +   de+e +e++  edee+eee+e+e++++++e++  +                      
  EEA21917.1  20 NpapavDSDEEGVRPDRRRGREVEVDEDAEDDNEGAEGEGRGDEDEGDEDE-AEDEEDEEEDEDEDDDDDDEDA-VSgrpkkrrrrggvnafieeeaGV 116
                 144444334444445555666666666666666666555555544333332.3344333332222222222222.224577778888888898655522 PP

        SDA1 163 eeeeeeeeeeeekekkkk.......................................k 181
                 ++++ee+e+ee++    +                                       +
  EEA21917.1 117 DDDDEEAEDEEDD----MgdvfgaeahpddldalplgaelddrrhrqldrqreleahM 170
                 3333333333333....24456888899999999999988876665553333222221 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5  40.4    0.0016       3.7     638     717 ..      44     132 ..      33     163 .. 0.58

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0016
  DNA_pol_phi 638 fedededeeddeeeeeeddeededseedddeeesdedeededdedvdeid.............elreklaealgesgededdddsdsDedmdD 717
                  ++++ ed+ +  e e+  de++ d++  + e+e+de+e++++d+d+d++d               ++ ++e+ g ++  +d++++d+++dm+D
   EEA21917.1  44 VDEDAEDDNEGAEGEGRGDEDEGDED--EAEDEEDEEEDEDEDDDDDDEDavsgrpkkrrrrgGVNAFIEEEAGVDD--DDEEAEDEEDDMGD 132
                  23333333333333333333333333..2222222222222222222222245678999999999999999999999..55555555555887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1021 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       917  (0.0511462); expected 358.6 (0.02)
Passed bias filter:                      552  (0.0307881); expected 358.6 (0.02)
Passed Vit filter:                       129  (0.00719505); expected 17.9 (0.001)
Passed Fwd filter:                        38  (0.00211947); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 1.07u 0.34s 00:00:01.41 Elapsed: 00:00:00.49
# Mc/sec: 6301.73
//
Query:       EEA21918.1  [L=317]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.5e-45  153.7   0.0    5.8e-17   62.1   0.0    4.5  5  Ank_2       Ankyrin repeats (3 copies)
    1.1e-31  108.8   0.0    1.6e-08   34.9   0.0    5.9  6  Ank_4       Ankyrin repeats (many copies)
    1.9e-24   83.1   0.0     0.0069   16.8   0.0    8.2  8  Ank_3       Ankyrin repeat
    2.1e-23   81.7   0.0      0.041   14.3   0.0    7.4  7  Ank         Ankyrin repeat
    4.3e-22   77.9   0.3    1.3e-05   25.4   0.0    6.9  7  Ank_5       Ankyrin repeats (many copies)
    1.9e-05   24.5   0.0    3.3e-05   23.7   0.0    1.3  1  F-box-like  F-box-like
  ------ inclusion threshold ------
      0.083   12.8   4.7        1.2    9.1   0.0    4.6  7  VWA_3_C     von Willebrand factor type A C-terminal domain


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.5   0.0    0.0048        12      50      81 ..      47      80 ..      27      82 .. 0.74
   2 !   43.0   0.0     2e-14   5.1e-11       1      82 [.      56     148 ..      56     149 .. 0.83
   3 !   62.1   0.0   2.3e-20   5.8e-17       2      82 ..     124     216 ..     123     217 .. 0.86
   4 !   28.5   0.0   6.5e-10   1.7e-06      28      76 ..     188     243 ..     188     249 .. 0.83
   5 !   36.4   0.0   2.3e-12   5.9e-09       1      73 [.     224     310 ..     224     316 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0048
       Ank_2 50 d.ndgr.tpLhyAarsghleivklLlekgadinl 81
                + ++g+ ++L +Aa++g++ +++l l+ ga i++
  EEA21918.1 47 NvRQGKsSALVWAAEHGRPATARLSLQAGARITA 80
                34445549**********9999988888998876 PP

  == domain 2  score: 43.0 bits;  conditional E-value: 2e-14
       Ank_2   1 LhlAakngnlelvklLl.egadpn.k.ngktaLhyAakngnleivklLleh....ad....ndgrtpLhyAarsghleivklLlekgadinlk 82 
                 L +Aa++g + + +l l +ga++  + +g+  + +Aa++g+le+vklLl+     +d       +t+L +A+++g + ivklLl+ +ad+n++
  EEA21918.1  56 LVWAAEHGRPATARLSLqAGARITaSkDGMPLISWAARGGHLEVVKLLLDTgkvqIDfrgsPIYKTALGWAIKCGDEAIVKLLLDAKADVNKR 148
                 6799**9988888888999999987447766666***************9666664454665568*******************999***986 PP

  == domain 3  score: 62.1 bits;  conditional E-value: 2.3e-20
       Ank_2   2 hlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlek.gadinlk 82 
                  +A+k g+  +vklLl ++ad+n  + +g t+L++Aak+g++ iv+lL+e         d +  t+L+yA+++g+++iv+ Lle  ++d+n+ 
  EEA21918.1 124 GWAIKCGDEAIVKLLLdAKADVNkrSiDGATPLIAAAKAGHEGIVRLLIETgkvgydmRDANSCTALFYAVSCGYEDIVERLLETgKVDVNIG 216
                 5788889889*************7538**********************956677675558889*******************8856788875 PP

  == domain 4  score: 28.5 bits;  conditional E-value: 6.5e-10
       Ank_2  28 taLhyAakngnleivklLleh....ad...ndgrtpLhyAarsghleivklLlekg 76 
                 taL+yA++ g+++iv+ Lle     ++    + r pL yAa+ g++ iv+lLle g
  EEA21918.1 188 TALFYAVSCGYEDIVERLLETgkvdVNigdFHCRLPLSYAAEMGYEGIVRLLLETG 243
                 8******************9667553355444679******************876 PP

  == domain 5  score: 36.4 bits;  conditional E-value: 2.3e-12
       Ank_2   1 LhlAakngnlelvklLl..egadpn...k....ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLl 73 
                 L +Aa+ g+  +v+lLl     +++         g t+L +A+k+g++ ivk+L++         d++g+t+L +A + g+ +i+klL 
  EEA21918.1 224 LSYAAEMGYEGIVRLLLetG--KVKayyGgtvvVGGTPLACAIKGGYVGIVKMLMDTgepvmhiPDQNGQTALSLAEEGGNADILKLLR 310
                 67999977566******642..33333414578899*******************9555665588899********998*******995 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       3.8   9.6e+03      19      30 ..      17      28 ..      13      32 .. 0.78
   2 !   28.7   0.0   5.5e-10   1.4e-06       3      55 .]      54     104 ..      52     111 .. 0.96
   3 !   34.9   0.0   6.2e-12   1.6e-08       3      55 .]     121     172 ..     119     172 .. 0.94
   4 !   32.6   0.0   3.3e-11   8.3e-08       3      55 .]     154     206 ..     154     206 .. 0.93
   5 !   19.9   0.0   3.2e-07   0.00082       2      54 ..     221     275 ..     220     276 .. 0.83
   6 !   11.9   0.0    0.0001      0.26       3      54 ..     258     309 ..     256     310 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 3.8
       Ank_4 19 lLlekgadinaq 30
                +++e+ +din +
  EEA21918.1 17 RCIETEKDINSV 28
                578999999998 PP

  == domain 2  score: 28.7 bits;  conditional E-value: 5.5e-10
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +aL +aa++gr  ++rl l+ ga i a+  ++G++++  Aa++g++e++klLl
  EEA21918.1  54 SALVWAAEHGRPATARLSLQAGARITAS--KDGMPLISWAARGGHLEVVKLLL 104
                 799*********************9996..99********************8 PP

  == domain 3  score: 34.9 bits;  conditional E-value: 6.2e-12
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 taL +a++ g++ +v+lLl+ +ad+n++ +++G t+l+ Aak g+  i++lL+
  EEA21918.1 121 TALGWAIKCGDEAIVKLLLDAKADVNKR-SIDGATPLIAAAKAGHEGIVRLLI 172
                 56668888899*****************.***********************8 PP

  == domain 4  score: 32.6 bits;  conditional E-value: 3.3e-11
       Ank_4   3 taLhyaaisgrlelvrlLlekgad.inaqdnrsGetalhiAakrgnveilklLl 55 
                 t+L +aa++g++ +vrlL+e+g+   +++ +++  tal +A++ g+ +i++ Ll
  EEA21918.1 154 TPLIAAAKAGHEGIVRLLIETGKVgYDMR-DANSCTALFYAVSCGYEDIVERLL 206
                 7999*****************76659999.********************9987 PP

  == domain 5  score: 19.9 bits;  conditional E-value: 3.2e-07
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrs......GetalhiAakrgnveilklL 54 
                 + +L yaa++g + +vrlLle+g+     +  +      G t+l +A+k+g+v i+k+L
  EEA21918.1 221 RLPLSYAAEMGYEGIVRLLLETGKV----KAYYggtvvvGGTPLACAIKGGYVGIVKML 275
                 679*******************875....2233344555889***************99 PP

  == domain 6  score: 11.9 bits;  conditional E-value: 0.0001
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54 
                 t+L  a++ g + +v+ L ++g  + + ++ +G+tal  A  +gn +ilklL
  EEA21918.1 258 TPLACAIKGGYVGIVKMLMDTGEPVMHIPDQNGQTALSLAEEGGNADILKLL 309
                 78999999**************8888887889*****************998 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.0     0.087   2.2e+02       4      19 ..      54      69 ..      52      78 .. 0.81
   2 !   11.8   0.0   0.00011      0.29       1      26 [.      83     108 ..      83     113 .. 0.84
   3 !   14.5   0.0   1.5e-05     0.039       3      30 ..     120     146 ..     119     147 .. 0.94
   4 !   11.7   0.0   0.00012      0.32       1      24 [.     151     174 ..     151     180 .. 0.88
   5 !   16.8   0.0   2.7e-06    0.0069       3      31 .]     187     215 ..     185     215 .. 0.95
   6 !    6.1   0.0    0.0084        22       4      24 ..     222     242 ..     221     248 .. 0.87
   7 ?    4.5   0.0     0.026        67       2      27 ..     256     280 ..     255     284 .. 0.87
   8 ?    3.2   0.0      0.07   1.8e+02       1      22 [.     289     309 ..     289     316 .. 0.79

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.087
       Ank_3  4 tpLhlAarsgnleivk 19
                ++L +Aa++g+++ ++
  EEA21918.1 54 SALVWAAEHGRPATAR 69
                89*********97554 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 0.00011
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkg 26 
                 +G+ ++ +Aar g+le+vk+Ll+   
  EEA21918.1  83 DGMPLISWAARGGHLEVVKLLLDTGK 108
                 5888999***************9555 PP

  == domain 3  score: 14.5 bits;  conditional E-value: 1.5e-05
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvn 30 
                  t+L +A+++g+ +ivk+Ll+   advn
  EEA21918.1 120 KTALGWAIKCGDEAIVKLLLD-AKADVN 146
                 69*******************.8****9 PP

  == domain 4  score: 11.7 bits;  conditional E-value: 0.00012
       Ank_3   1 nGetpLhlAarsgnleivkfLlen 24 
                 +G tpL  Aa++g+  iv++L+e 
  EEA21918.1 151 DGATPLIAAAKAGHEGIVRLLIET 174
                 699*******************94 PP

  == domain 5  score: 16.8 bits;  conditional E-value: 2.7e-06
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvna 31 
                 +t+L++A+++g  +iv+ Lle   +dvn+
  EEA21918.1 187 CTALFYAVSCGYEDIVERLLETGKVDVNI 215
                 7**************************97 PP

  == domain 6  score: 6.1 bits;  conditional E-value: 0.0084
       Ank_3   4 tpLhlAarsgnleivkfLlen 24 
                  pL +Aa+ g   iv++Lle 
  EEA21918.1 222 LPLSYAAEMGYEGIVRLLLET 242
                 69*****************94 PP

  == domain 7  score: 4.5 bits;  conditional E-value: 0.026
       Ank_3   2 GetpLhlAarsgnleivkfLlenkga 27 
                 G tpL +A++ g + ivk+L +  g 
  EEA21918.1 256 GGTPLACAIKGGYVGIVKMLMD-TGE 280
                 679*****************99.565 PP

  == domain 8  score: 3.2 bits;  conditional E-value: 0.07
       Ank_3   1 nGetpLhlAarsgnleivkfLl 22 
                 nG+t+L lA + gn +i+k Ll
  EEA21918.1 289 NGQTALSLAEEGGNADILK-LL 309
                 79*******9999999555.44 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.1   0.0   0.00017      0.42       7      24 ..      88     107 ..      83     112 .. 0.79
   2 !   13.1   0.0   4.1e-05       0.1       4      30 ..     121     148 ..     120     150 .. 0.87
   3 !   13.3   0.0   3.4e-05     0.087       1      24 [.     151     175 ..     151     183 .. 0.89
   4 !   14.3   0.0   1.6e-05     0.041       3      31 ..     187     217 ..     185     218 .. 0.92
   5 !    6.0   0.0     0.007        18       5      24 ..     223     243 ..     222     247 .. 0.79
   6 ?    5.0   0.0     0.015        38       4      24 ..     258     279 ..     256     285 .. 0.83
   7 !    8.6   0.0     0.001       2.6       1      21 [.     289     309 ..     289     315 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00017
                 H.HHHHHTTHHHHHHHH.TT CS
         Ank   7 H.lAatngkkriiklLL.hG 24 
                   +Aa++g+++++klLL  G
  EEA21918.1  88 IsWAARGGHLEVVKLLLdTG 107
                 4489*************667 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 4.1e-05
                 BHHHHHHHHTTHHHHHHHH.TTTSTTCB CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnlnal 30 
                 T+L +A+ +g++ i+klLL   A++n +
  EEA21918.1 121 TALGWAIKCGDEAIVKLLLdAKADVNKR 148
                 9999***99**********446****87 PP

  == domain 3  score: 13.3 bits;  conditional E-value: 3.4e-05
                 TSBBHHHHHHHHTTHHHHHHHH.TT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hG 24 
                 dG TPL  Aa  g++ i++lL+  G
  EEA21918.1 151 DGATPLIAAAKAGHEGIVRLLIeTG 175
                 899*******888899*****9666 PP

  == domain 4  score: 14.3 bits;  conditional E-value: 1.6e-05
                 BBHHHHHHHHTTHHHHHHHH.TT.TSTTCBT CS
         Ank   3 nTPLHlAatngkkriiklLL.hG.Anlnald 31 
                 +T+L +A+++g ++i++ LL  G  ++n+ d
  EEA21918.1 187 CTALFYAVSCGYEDIVERLLeTGkVDVNIGD 217
                 7*******************98999**9977 PP

  == domain 5  score: 6.0 bits;  conditional E-value: 0.007
                 HHHHHHHHTTHHHHHHHH.TT CS
         Ank   5 PLHlAatngkkriiklLL.hG 24 
                 PL +Aa  g + i++lLL  G
  EEA21918.1 223 PLSYAAEMGYEGIVRLLLeTG 243
                 999***555555******767 PP

  == domain 6  score: 5.0 bits;  conditional E-value: 0.015
                 BHHHHHHHHTTHHHHHHHH.TT CS
         Ank   4 TPLHlAatngkkriiklLL.hG 24 
                 TPL +A+ +g + i+k+L   G
  EEA21918.1 258 TPLACAIKGGYVGIVKMLMdTG 279
                 9******888888***998556 PP

  == domain 7  score: 8.6 bits;  conditional E-value: 0.001
                 TSBBHHHHHHHHTTHHHHHHH CS
         Ank   1 dGnTPLHlAatngkkriiklL 21 
                 +G T+L lA  +g+++i+klL
  EEA21918.1 289 NGQTALSLAEEGGNADILKLL 309
                 7*******889999*****87 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0     0.056   1.4e+02      12      35 ..      49      71 ..      45      87 .. 0.73
   2 !   10.3   0.0   0.00027      0.68      15      36 ..      83     104 ..      72     112 .. 0.83
   3 ?    5.1   0.0     0.012        31      18      43 ..     121     146 ..     109     146 .. 0.85
   4 !   25.4   0.0   5.1e-09   1.3e-05       1      56 []     138     193 ..     138     193 .. 0.95
   5 !   19.9   0.0   2.7e-07   0.00069      15      56 .]     187     227 ..     182     227 .. 0.93
   6 !   12.3   0.0   6.4e-05      0.16      16      56 .]     257     297 ..     250     297 .. 0.83
   7 !    6.1   0.0    0.0056        14      12      35 ..     286     309 ..     283     315 .. 0.91

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.056
       Ank_5 12 ldgggntpLhvAakygaadvvrlL 35
                + +g+ ++L +Aa++g++  +rl 
  EEA21918.1 49 R-QGKSSALVWAAEHGRPATARLS 71
                3.44559*********98766665 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00027
       Ank_5  15 ggntpLhvAakygaadvvrlLl 36 
                 +g+  + +Aa++g+++vv+lLl
  EEA21918.1  83 DGMPLISWAARGGHLEVVKLLL 104
                 56667889*************9 PP

  == domain 3  score: 5.1 bits;  conditional E-value: 0.012
       Ank_5  18 tpLhvAakygaadvvrlLlargadln 43 
                 t+L +A+k+g   +v+lLl+  ad n
  EEA21918.1 121 TALGWAIKCGDEAIVKLLLDAKADVN 146
                 8999***************7777765 PP

  == domain 4  score: 25.4 bits;  conditional E-value: 5.1e-09
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltaldlA 56 
                 Ll++  advn +  +g tpL+ Aak+g+  +vrlL+    + ++++d++  tal +A
  EEA21918.1 138 LLDAK-ADVNKRSIDGATPLIAAAKAGHEGIVRLLIeTGKVGYDMRDANSCTALFYA 193
                 89998.**********************************************99665 PP

  == domain 5  score: 19.9 bits;  conditional E-value: 2.7e-07
       Ank_5  15 ggntpLhvAakygaadvvrlLl.argadlnltdsrGltaldlA 56 
                 +  t+L +A+++g+ d+v++Ll    +d n+ d++++++l +A
  EEA21918.1 187 C--TALFYAVSCGYEDIVERLLeTGKVDVNIGDFHCRLPLSYA 227
                 4..9************************************998 PP

  == domain 6  score: 12.3 bits;  conditional E-value: 6.4e-05
       Ank_5  16 gntpLhvAakygaadvvrlLl.argadlnltdsrGltaldlA 56 
                 g tpL  A+k+g+  +v++L+   +    + d +G+tal lA
  EEA21918.1 257 G-TPLACAIKGGYVGIVKMLMdTGEPVMHIPDQNGQTALSLA 297
                 3.9******************966666666776689999887 PP

  == domain 7  score: 6.1 bits;  conditional E-value: 0.0056
       Ank_5  12 ldgggntpLhvAakygaadvvrlL 35 
                 +d++g+t+L +A ++g+ad+++lL
  EEA21918.1 286 PDQNGQTALSLAEEGGNADILKLL 309
                 7999****************9987 PP

>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.7   0.0   1.3e-08   3.3e-05       2      43 ..       5      45 ..       4      48 .. 0.92

  Alignments for each domain:
  == domain 1  score: 23.7 bits;  conditional E-value: 1.3e-08
  F-box-like  2 srLPdEiLlqIFsyLpps.dLlrlalVCrrWrrvaldtplLWr 43
                ++LP+EiLl I ++++++ d+ ++++++ r++ +   tp+L++
  EEA21918.1  5 LDLPTEILLLIGRCIETEkDINSVCQTSHRFHALF--TPYLYK 45
                79*************7666***************9..99**97 PP

>> VWA_3_C  von Willebrand factor type A C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0         2   5.1e+03       3      14 ..      59      70 ..      59      71 .. 0.89
   2 ?   -1.9   0.0       1.3   3.3e+03       3      15 ..      91     103 ..      91     109 .. 0.80
   3 ?   -2.4   0.0       1.8   4.5e+03       4      15 ..     127     138 ..     126     140 .. 0.82
   4 ?    0.6   0.0       0.2   5.2e+02       3      15 ..     159     171 ..     158     177 .. 0.89
   5 ?   -3.2   0.0       3.1   7.9e+03       3      16 ..     193     206 ..     193     214 .. 0.64
   6 ?   -0.1   0.0      0.34   8.6e+02       3      18 ..     227     242 ..     225     253 .. 0.74
   7 ?    9.1   0.0   0.00047       1.2       2      20 ..     296     314 ..     295     316 .. 0.88

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 2
                HHHHT-HHHHHH CS
     VWA_3_C  3 AaeSGnedtakl 14
                Aae G+  ta+l
  EEA21918.1 59 AAEHGRPATARL 70
                899999999987 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 1.3
                 HHHHT-HHHHHHH CS
     VWA_3_C   3 AaeSGnedtaklL 15 
                 Aa  G+ + +klL
  EEA21918.1  91 AARGGHLEVVKLL 103
                 5667999999998 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 1.8
                 HHHT-HHHHHHH CS
     VWA_3_C   4 aeSGnedtaklL 15 
                    G e  +klL
  EEA21918.1 127 IKCGDEAIVKLL 138
                 567999****99 PP

  == domain 4  score: 0.6 bits;  conditional E-value: 0.2
                 HHHHT-HHHHHHH CS
     VWA_3_C   3 AaeSGnedtaklL 15 
                 Aa  G+e+ ++lL
  EEA21918.1 159 AAKAGHEGIVRLL 171
                 7889*******99 PP

  == domain 5  score: -3.2 bits;  conditional E-value: 3.1
                 HHHHT-HHHHHHHH CS
     VWA_3_C   3 AaeSGnedtaklLr 16 
                 A+  G ed + +L 
  EEA21918.1 193 AVSCGYEDIVERLL 206
                 56677888877664 PP

  == domain 6  score: -0.1 bits;  conditional E-value: 0.34
                 HHHHT-HHHHHHHHTT CS
     VWA_3_C   3 AaeSGnedtaklLrkV 18 
                 Aae G e+ ++lL   
  EEA21918.1 227 AAEMGYEGIVRLLLET 242
                 8999999999999765 PP

  == domain 7  score: 9.1 bits;  conditional E-value: 0.00047
                 HHHHHT-HHHHHHHHTTEE CS
     VWA_3_C   2 LAaeSGnedtaklLrkVVd 20 
                 LA+e Gn d  klLr  Vd
  EEA21918.1 296 LAEEGGNADILKLLRPEVD 314
                 9*************97665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (317 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       363  (0.0202465); expected 358.6 (0.02)
Passed bias filter:                      356  (0.0198561); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 2206.00
//
Query:       EEA21919.1  [L=541]
Description: acyl-CoA dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.1e-43  147.6   0.4    4.7e-43  147.0   0.4    1.3  1  Acyl-CoA_dh_1  Acyl-CoA dehydrogenase, C-terminal domain
    5.8e-23   80.9   0.2      1e-22   80.2   0.2    1.4  1  Acyl-CoA_dh_M  Acyl-CoA dehydrogenase, middle domain
    4.9e-20   72.3   0.0    1.1e-19   71.2   0.0    1.6  1  Acyl-CoA_dh_N  Acyl-CoA dehydrogenase, N-terminal domain
    3.5e-18   65.5   0.2    6.5e-18   64.6   0.2    1.5  1  Cyt-b5         Cytochrome b5-like Heme/Steroid binding domain
    9.8e-12   45.3   0.0    1.7e-11   44.5   0.0    1.3  1  Acyl-CoA_dh_2  Acyl-CoA dehydrogenase, C-terminal domain


Domain annotation for each model (and alignments):
>> Acyl-CoA_dh_1  Acyl-CoA dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  147.0   0.4   1.3e-46   4.7e-43       1     148 [.     373     529 ..     373     531 .. 0.96

  Alignments for each domain:
  == domain 1  score: 147.0 bits;  conditional E-value: 1.3e-46
                    TBHHHHHTTTT--S-----..-SHHHHHHHHHHHHHHHTSB-CC-BGGGSHHHHHHHHHHHHHHHHHHHHHHHHHH--------......HHHHHH CS
  Acyl-CoA_dh_1   1 gkGfrvametlnheRlavaaaalglarraleealeyarrrkafgkplidhqlvreklaemaaeleaarllvyraaealdagkpd......raeasm 90 
                    ++Gf+v+m+++nheR+++++++l++ r ++ee+++ya++r++fgk+lidh+++r kla+ma ++eaa +++++++++++ ++++      + +++ 
     EEA21919.1 373 NQGFKVIMTNFNHERIGIIIQSLRFSRVCYEESVKYANKRRTFGKKLIDHPVIRMKLADMARQIEAAYNWLENVVYQAQSMEDTeamlkmGGAIAG 468
                    79**************************************************************************99999999999*99999*** PP

                    HHHHHHHHHHHHHHHHHHHHGGGTTSGGGH...HHHHHHHTHHHHHSSS-HHHHHHHHHHH CS
  Acyl-CoA_dh_1  91 aKlfaselaqevadlamqllGgaGyleeyp...verlyrdarvlrigeGtseiqrniiarr 148
                    +K++ +++++ +a++a q++Gg +y+++++   +erlyrd+r++ i +G++ei++++  r+
     EEA21919.1 469 LKAQSTKTFEFCAREASQIFGGLSYSRGGQggkIERLYRDVRAYAIPGGSEEIMLDLSIRQ 529
                    *************************86666677**********************987765 PP

>> Acyl-CoA_dh_M  Acyl-CoA dehydrogenase, middle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.2   0.2   2.8e-26     1e-22       1      96 [.     266     360 ..     266     361 .. 0.95

  Alignments for each domain:
  == domain 1  score: 80.2 bits;  conditional E-value: 2.8e-26
                    EEE---SS-SS-GGG---EE.EEETT.EEEEEEEEEEEETTTT-SEEEEEEETS-------EEEEEEE..GGGEEE-----BSS-TTS-EEEEEEE CS
  Acyl-CoA_dh_M   1 afalTEpqaGsdvasvktta.aerdggeyvlnGeKiwitnaaiatlalvlartekpdrarglslflvprdapgvsvrrieeklGlrglptgelvfe 95 
                    ++a+TEp+aGsdva+++ +a  ++dg++y++nGeK witn+ +a++++v +rt+++   +g+s++lv+r + gvs rr++   G+ +  t++++fe
     EEA21919.1 266 CLAITEPDAGSDVANLTCEAkLSEDGKHYIVNGEKKWITNGIWADYFTVAVRTGGEG-MNGISVLLVERENGGVSTRRMD-CQGVWSSGTTYITFE 359
                    9*******************99999999************************88777.*********************5.799999999999999 PP

                    . CS
  Acyl-CoA_dh_M  96 d 96 
                    d
     EEA21919.1 360 D 360
                    8 PP

>> Acyl-CoA_dh_N  Acyl-CoA dehydrogenase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.2   0.0     3e-23   1.1e-19       1     113 []     137     262 ..     137     262 .. 0.90

  Alignments for each domain:
  == domain 1  score: 71.2 bits;  conditional E-value: 3e-23
                    THHHHHHHHHHHHHHHHHTHHHHHHHHHHTSGHHHHHHHHHH....TTCTSTTS-GGGTS--S........-HHHHHHHHHHHHHH-HHHHH.HHH CS
  Acyl-CoA_dh_N   1 teeqealrdtvrefaeeelaphaaewdeegefprelwkklae....lGllgitvpeeygGagl........dyleaaivaeelaradaglal.llg 83 
                    +e++ alr++vre++e e++p+++ewde +++p++++k+++e    +Gllg+++p ey  a +        d ++++iv++el+r+++g+ +  l 
     EEA21919.1 137 NETHAALRAEVREWVESEIEPYVTEWDEGKKVPDSIYKQMGErgylAGLLGVHFPAEYTQARVksvppemwDHFHELIVTDELSRTGSGGLVwNLI 232
                    589***********************9999***********955555899*********9986677787779*************99987666777 PP

                    HHHHTTHHHHHHHS-HHHHHHHHHHHHTTS CS
  Acyl-CoA_dh_N  84 vhsslvapailrfGteeqkrryLpklasge 113
                     + ++++p++++fG +   +r Lp +++g+
     EEA21919.1 233 GGFGIGCPPLVKFGKKPLLDRILPGILAGD 262
                    7999***********************996 PP

>> Cyt-b5  Cytochrome b5-like Heme/Steroid binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.6   0.2   1.8e-21   6.5e-18       1      73 [.       6      77 ..       6      78 .. 0.95

  Alignments for each domain:
  == domain 1  score: 64.6 bits;  conditional E-value: 1.8e-21
                EHHHHTTTECTTEEEEEETTEEEECTTTCCCSTTCSHHHHTTTTSBBHHHHHHTTGGCHHHHHHHHGGEEEEE CS
      Cyt-b5  1 tleelskhngkndlwvairgkVYDvskflskhpGgesailkyaGkDateafksvvhsekdaekllkkylvGkl 73
                ++e++++hn++++lw++i+  VYDv+kf ++hpG + ++++ aGkDa++ f+++ h+e +++k+  ++ +G l
  EEA21919.1  6 SKEQVAAHNKSDSLWIVIDEDVYDVTKFQDDHPGFRIVLQRVAGKDASKQFWKY-HNEGILKKYKSQLQIGSL 77
                579***************************************************.****99**9777999976 PP

>> Acyl-CoA_dh_2  Acyl-CoA dehydrogenase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.5   0.0   4.7e-15   1.7e-11      12     126 ..     399     512 ..     389     514 .. 0.86

  Alignments for each domain:
  == domain 1  score: 44.5 bits;  conditional E-value: 4.7e-15
                    HHHHHHHHHHHHHHHCTTT-------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT----HHHHHHHHHHHHHHHHHHHHHHHHHHHHCGG CS
  Acyl-CoA_dh_2  12 raalaefvelarervrassgekladdpatqlalaeaaarldAAralleraaaraealaaagkevtvedraearraaalavelaiaavdalfeaaGg 107
                    r +++e v++a++r +  +g+kl d+p++ ++la++a +++AA   le+++++a+ + ++++    ++   ++  +a  +++   +++++ +++Gg
     EEA21919.1 399 RVCYEESVKYANKRRT--FGKKLIDHPVIRMKLADMARQIEAAYNWLENVVYQAQSMEDTEAM--LKMGGAIAGLKAQSTKTFEFCAREASQIFGG 490
                    6688999*******99..***********************************7765554444..4667777777********************* PP

                    GGGB...TT-HHHHHHHHHHHH CS
  Acyl-CoA_dh_2 108 salr...kesplqRlwRDahaa 126
                     ++    +  +++Rl+RD++a 
     EEA21919.1 491 LSYSrggQGGKIERLYRDVRAY 512
                    ***73335789********996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (541 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       411  (0.0229238); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.56u 0.25s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 3813.72
//
Query:       EEA21920.1  [L=1118]
Description: 26S proteasome regulatory subunit Rpn2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      2e-55  187.1   9.1      2e-55  187.1   9.1    1.9  2  RPN2_C           26S proteasome regulatory subunit RPN2 C-ter
    1.2e-37  126.5  18.2    7.5e-10   38.7   0.0    8.8  8  PC_rep           Proteasome/cyclosome repeat
    1.2e-22   80.1   0.2    2.7e-15   56.5   0.0    4.8  5  HEAT_2           HEAT repeats
    1.2e-07   32.0   0.1     0.0012   19.3   0.1    5.7  7  HEAT_EZ          HEAT-like repeat
      3e-06   27.0   0.0          4    7.9   0.0    5.8  5  HEAT             HEAT repeat
    9.2e-06   25.8   1.2      0.013   15.6   0.0    3.7  4  Cnd1             non-SMC mitotic condensation complex subunit
  ------ inclusion threshold ------
      0.069   13.4   0.2         30    4.9   0.0    3.1  2  ANAPC3           Anaphase-promoting complex, cyclosome, subun
       0.19   12.5   2.9          1   10.2   0.0    3.6  3  HEAT_PBS         PBS lyase HEAT-like repeat
          1    9.3   3.0          1    9.3   0.1    2.4  3  Clathrin_H_link  Clathrin-H-link


Domain annotation for each model (and alignments):
>> RPN2_C  26S proteasome regulatory subunit RPN2 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.3       4.2   8.3e+03      89      99 ..     363     378 ..     345     403 .. 0.46
   2 !  187.1   9.1     1e-58     2e-55       1     160 []     865    1034 ..     865    1034 .. 0.91

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 4.2
                 ----------.....- CS
      RPN2_C  89 kekkekekee.....e 99 
                 + ++e+++e+     +
  EEA21920.1 363 NANEEAATEAdsllaN 378
                 1111111111112221 PP

  == domain 2  score: 187.1 bits;  conditional E-value: 1e-58
                  -BEEEEETTTBEE--EEEEES-TTTTSSS-S--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHG...............----------------- CS
      RPN2_C    1 TaiIglnkdLkiPkfefksnakpslFaYPpeleekkekekekvatAvLSttakakarakkkekek..............eeeekeedkmdvdeekee 83  
                  Ta+Ig+++ L++P f+f+sn++pslF+YPpe+++k+++++ekv+tAvLStt++ak+ra+++ek++              + + +  + m++de+  +
  EEA21920.1  865 TAVIGVDQSLEVPVFQFHSNTRPSLFDYPPEQQVKADEAPEKVKTAVLSTTNQAKRRAQRREKQQrresmdvdqtpttpKVSGQLPERMETDESAVK 961 
                  9****************************************************************99999999998877666777888888885555 PP

                  -----------------SS----SSEEEEESSSB--TTCCTTEEE-SSSSEEESSS-SSSSEEEEEESSTSSSSSEE CS
      RPN2_C   84 kekkekekkekekeeekkkkekektfekleNpaRVlpaQlkyisfkkdsrYkpvkkkgtgGivllkdkkpeeeeelv 160 
                  + +++ke++++e   +kkk+ekek++++leN++RVlpaQlky++f +d rY+pvk+ +tgG+v++ dkkp+e++e++
  EEA21920.1  962 EGEEAKEATKEEG--QKKKAEKEKVGYELENMSRVLPAQLKYLTF-PDPRYEPVKR-PTGGVVVVLDKKPDEPRETI 1034
                  5555555555544..9*****************************.**********.*****************987 PP

>> PC_rep  Proteasome/cyclosome repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   1.4e-06    0.0029       2      27 ..     478     502 ..     477     506 .. 0.91
   2 !   12.8   0.0   6.2e-05      0.12       1      33 [.     520     551 ..     520     553 .. 0.89
   3 !   12.4   0.2   8.5e-05      0.17       1      33 [.     555     587 ..     555     589 .. 0.93
   4 !   24.4   0.0   1.3e-08   2.5e-05       4      34 ..     593     623 ..     590     624 .. 0.94
   5 ?   -1.9   0.3       2.9   5.7e+03       4      22 ..     627     645 ..     626     647 .. 0.82
   6 !    6.9   0.0    0.0048       9.6       8      34 ..     667     694 ..     667     695 .. 0.83
   7 !   38.7   0.0   3.8e-13   7.5e-10       1      35 []     730     764 ..     730     764 .. 0.97
   8 !   18.2   0.6   1.2e-06    0.0025       1      24 [.     808     830 ..     808     833 .. 0.93

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 1.4e-06
                 HHHHHHHHCTTSTCHHHHHHHHHHHH CS
      PC_rep   2 AllALGlihaGsgneeaislLkpyls 27 
                 A++ALG+ih G+ +e +++lL pyl+
  EEA21920.1 478 ATAALGVIHKGNLSE-GRKLLAPYLP 502
                 99*********7777.********98 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 6.2e-05
                 HHHHHHHHHCTTSTCHHHHHHHHHHHHHHSSHH CS
      PC_rep   1 GAllALGlihaGsgneeaislLkpylsdtsaev 33 
                 G+l+A Gli+a++g   a +l++++ ++ + ev
  EEA21920.1 520 GSLFAYGLIYANHGGA-AVELIRDHFKKATEEV 551
                 899*************.*******999877776 PP

  == domain 3  score: 12.4 bits;  conditional E-value: 8.5e-05
                 HHHHHHHHHCTTSTCHHHHHHHHHHHHHHSSHH CS
      PC_rep   1 GAllALGlihaGsgneeaislLkpylsdtsaev 33 
                 G +l+LG++++ +g+e + + Lk++l+ +sa+ 
  EEA21920.1 555 GGALGLGVAGMATGDEGIWEDLKSVLYTDSAVN 587
                 789************************999976 PP

  == domain 4  score: 24.4 bits;  conditional E-value: 1.3e-08
                 HHHHHHCTTSTCHHHHHHHHHHHHHHSSHHH CS
      PC_rep   4 lALGlihaGsgneeaislLkpylsdtsaevr 34 
                 lA+Gl+++G+gn  +++ + +y+++t++e++
  EEA21920.1 593 LAMGLVMLGTGNMKLLEEMVQYAHETQHEKI 623
                 9***************************986 PP

  == domain 5  score: -1.9 bits;  conditional E-value: 2.9
                 HHHHHHCTTSTCHHHHHHH CS
      PC_rep   4 lALGlihaGsgneeaislL 22 
                 lALG++   +g++ea + L
  EEA21920.1 627 LALGMALIMYGRQEAADEL 645
                 8999998888888888877 PP

  == domain 6  score: 6.9 bits;  conditional E-value: 0.0048
                 HHCTTSTCH.HHHHHHHHHHHHHSSHHH CS
      PC_rep   8 lihaGsgne.eaislLkpylsdtsaevr 34 
                 l+++G+g++ ++++lL+  +sd +++vr
  EEA21920.1 667 LAYCGTGSNkAVRKLLHVAVSDVNDDVR 694
                 89*******9999999987777777765 PP

  == domain 7  score: 38.7 bits;  conditional E-value: 3.8e-13
                 HHHHHHHHHCTTSTCHHHHHHHHHHHHHHSSHHHH CS
      PC_rep   1 GAllALGlihaGsgneeaislLkpylsdtsaevra 35 
                 GA++ALG+ +aG+g +eai+lL+p+l+d++++vr+
  EEA21920.1 730 GAAMALGISCAGTGLDEAIDLLEPMLKDPTDFVRQ 764
                 9******************************9985 PP

  == domain 8  score: 18.2 bits;  conditional E-value: 1.2e-06
                 HHHHHHHHHCTTSTCHHHHHHHHH CS
      PC_rep   1 GAllALGlihaGsgneeaislLkp 24 
                 G++lALG+i+aG g++ +isl  +
  EEA21920.1 808 GCALALGIIDAG-GRNCTISLQTQ 830
                 9***********.******99765 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.2   0.0    0.0066        13       4      57 ..      10      68 ..       7      76 .. 0.77
   2 ?   -0.8   0.0         1     2e+03      51      81 ..     296     326 ..     271     350 .. 0.61
   3 !   10.1   0.0   0.00042      0.83      27      80 ..     602     658 ..     588     666 .. 0.69
   4 !   27.5   0.0   1.6e-09   3.1e-06       5      88 .]     612     702 ..     604     702 .. 0.77
   5 !   56.5   0.0   1.4e-18   2.7e-15       3      88 .]     680     771 ..     678     771 .. 0.89

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0066
      HEAT_2  4 LlqalendpdpevrraairaLg......rignpealpaLvellededpavRraaaeaLga 57
                L+ +l + pdpe+r  a+++L       + +  +a+p +  l ede    R+ aa  +++
  EEA21920.1 10 LVGFL-SEPDPELRVFALKTLDaevdvlWTDIVDAIPQIEALYEDETFPERELAALVASK 68
                55567.789999999999999987777666667899999999999887777777776665 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 1
      HEAT_2  51 aaeaLgaigdpe.alpaLkellddddddvvRe 81 
                 +a+  + +++++ a ++L++l d d+  + R+
  EEA21920.1 296 IAKCVVYLDEHSmATEILRQLIDKDE-TRART 326
                 44444444443325556666554433.33333 PP

  == domain 3  score: 10.1 bits;  conditional E-value: 0.00042
      HEAT_2  27 ignpealpaLvell.ededpavRraaae..aLgaigdpealpaLkellddddddvvR 80 
                  gn ++l+ +v+++ e++++ + r  a   aL  +g++ea++ L   l+ d+d++ R
  EEA21920.1 602 TGNMKLLEEMVQYAhETQHEKIVRGLALgmALIMYGRQEAADELINGLLGDPDPYLR 658
                 467777888888887777777666666512444557888888888888888887777 PP

  == domain 4  score: 27.5 bits;  conditional E-value: 1.6e-09
      HEAT_2   5 lqalendpdpe.vrraai.raLgrignpealpaLve.llededpavRraaae..aLgaig..dpealpaLkellddddddvvReaAaeaLa 88 
                 +q++++  +++ vr  a+ +aL  +g +ea + L++ ll d+dp+ R+  ++  aL+ +g  +++a++ L++ + +d +d+vR+ A+ +L+
  EEA21920.1 612 VQYAHETQHEKiVRGLALgMALIMYGRQEAADELINgLLGDPDPYLRYGGIMtvALAYCGtgSNKAVRKLLHVAVSDVNDDVRRVAVMSLG 702
                 4555443333325554444666699***********666************955666775337*************************996 PP

  == domain 5  score: 56.5 bits;  conditional E-value: 1.4e-18
      HEAT_2   3 aLlqalendpdpevrraairaLg..rignpealpaLvell.ededpavRraaaeaLgai....gdpealpaLkellddddddvvReaAaeaLa 88 
                 +Ll ++++d +++vrr a+++Lg   ++  +++p +vell e+ +p+vR+ aa+aLg      g++ea+++L+ +l+d+  d+vR+ A+++La
  EEA21920.1 680 KLLHVAVSDVNDDVRRVAVMSLGfiLFRKHQSVPRMVELLsESYNPHVRYGAAMALGIScagtGLDEAIDLLEPMLKDP-TDFVRQGALISLA 771
                 7999999****************88889999*********889**************77665579*********99866.5677999999986 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0       8.5   1.7e+04      33      52 ..      10      29 ..       9      29 .. 0.78
   2 ?   -2.1   0.0         3   5.9e+03      10      44 ..      83     121 ..      76     123 .. 0.75
   3 ?    3.3   0.0     0.063   1.2e+02      25      48 ..     308     326 ..     302     328 .. 0.85
   4 ?   -3.6   0.0         9   1.8e+04       7      27 ..     478     502 ..     476     503 .. 0.65
   5 ?   -2.3   0.0       3.4   6.7e+03      30      34 ..     624     628 ..     599     659 .. 0.57
   6 !    9.0   0.0     0.001         2       4      53 ..     694     736 ..     691     737 .. 0.76
   7 !   19.3   0.1   5.8e-07    0.0012       1      52 [.     725     770 ..     725     772 .. 0.86

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 8.5
     HEAT_EZ 33 LlalLnddsdeVRaaAagaL 52
                L+ +L+ +++e R  A+ +L
  EEA21920.1 10 LVGFLSEPDPELRVFALKTL 29
                77788888889998888776 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 3
     HEAT_EZ  10 aLGr....laggepellqplvpeilpaLlalLnddsdeV 44 
                 aLG+     +  ++e  q+ +++ ++ ++al  + +++V
  EEA21920.1  83 ALGAgkllNLDKGGEFEQTIISKCIDTFIALSASRHPSV 121
                 666666554456666678999999999999999999887 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.063
     HEAT_EZ  25 lvpeilpaLlalLnddsdeVRaaA 48 
                 + +eil++L+     d+de+Ra +
  EEA21920.1 308 MATEILRQLI-----DKDETRART 326
                 6789******.....*****9876 PP

  == domain 4  score: -3.6 bits;  conditional E-value: 9
     HEAT_EZ   7 AawaLGr....laggepellqplvp 27 
                 A +aLG      +++++ ll+p++p
  EEA21920.1 478 ATAALGVihkgNLSEGRKLLAPYLP 502
                 6677776666645577777777776 PP

  == domain 5  score: -2.3 bits;  conditional E-value: 3.4
     HEAT_EZ  30 lpaLl 34 
                 ++ L+
  EEA21920.1 624 VRGLA 628
                 44444 PP

  == domain 6  score: 9.0 bits;  conditional E-value: 0.001
     HEAT_EZ   4 RraAawaLGrlaggepellqplvpeilpaLlalL.nddsdeVRaaAagaLg 53 
                 Rr A++ LG   +  ++  q      +p ++ lL ++ +++VR+ Aa aLg
  EEA21920.1 694 RRVAVMSLG---FILFRKHQ-----SVPRMVELLsESYNPHVRYGAAMALG 736
                 555666666...66555555.....689999999899*************9 PP

  == domain 7  score: 19.3 bits;  conditional E-value: 5.8e-07
     HEAT_EZ   1 wrvRraAawaLGrlaggepellqplvpeilpaLlalLnddsdeVRaaAagaL 52 
                 + vR +Aa+aLG   ++++  l     e++++L ++L+d+ d VR+ A++ L
  EEA21920.1 725 PHVRYGAAMALGI--SCAGTGLD----EAIDLLEPMLKDPTDFVRQGALISL 770
                 579*********5..33566666....**********************988 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.25     5e+02       6      24 ..      11      29 ..       8      31 .. 0.85
   2 ?   -1.2   0.0       1.7   3.4e+03       7      18 ..     648     659 ..     644     663 .. 0.79
   3 ?    5.6   0.0     0.012        23       9      27 ..     686     704 ..     678     706 .. 0.84
   4 ?    3.5   0.0     0.056   1.1e+02       3      25 ..     713     736 ..     712     741 .. 0.78
   5 !    7.9   0.0     0.002         4       2      25 ..     748     771 ..     747     774 .. 0.89

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.25
                HHHHT-SSHHHHHHHHHHH CS
        HEAT  6 lkllsDpspeVReaAakaL 24
                +  ls p+pe R  A+k+L
  EEA21920.1 11 VGFLSEPDPELRVFALKTL 29
                566899***********99 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 1.7
                 HHHT-SSHHHHH CS
        HEAT   7 kllsDpspeVRe 18 
                  ll Dp+p  R+
  EEA21920.1 648 GLLGDPDPYLRY 659
                 568*****9986 PP

  == domain 3  score: 5.6 bits;  conditional E-value: 0.012
                 HT-SSHHHHHHHHHHHHHH CS
        HEAT   9 lsDpspeVReaAakaLgal 27 
                  sD + +VR+ A+ +Lg +
  EEA21920.1 686 VSDVNDDVRRVAVMSLGFI 704
                 499*************966 PP

  == domain 4  score: 3.5 bits;  conditional E-value: 0.056
                 HHHHHHH.T-SSHHHHHHHHHHHH CS
        HEAT   3 Plllkll.sDpspeVReaAakaLg 25 
                 P +++ll ++ +p+VR+ Aa aLg
  EEA21920.1 713 PRMVELLsESYNPHVRYGAAMALG 736
                 56666665555899*********9 PP

  == domain 5  score: 7.9 bits;  conditional E-value: 0.002
                 HHHHHHHHT-SSHHHHHHHHHHHH CS
        HEAT   2 lPlllkllsDpspeVReaAakaLg 25 
                 ++ll  +l+Dp  +VR+ A+ +L+
  EEA21920.1 748 IDLLEPMLKDPTDFVRQGALISLA 771
                 67899**************99987 PP

>> Cnd1  non-SMC mitotic condensation complex subunit 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.1         1     2e+03      86     155 ..     272     345 ..     253     352 .. 0.55
   2 ?   -3.2   0.0       3.9   7.8e+03      73     107 ..     385     420 ..     366     431 .. 0.76
   3 !    6.2   0.0    0.0047       9.4      26      89 ..     646     708 ..     623     724 .. 0.75
   4 !   15.6   0.0   6.4e-06     0.013       2      73 ..     727     802 ..     726     824 .. 0.83

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 1
        Cnd1  86 seksenaiynllpdiisklsd....alne..csewgqitilefLlsyipkdkqeaeslveklcprlqhansavvla 155
                 s +  n+i++l  ++++++ +    a+ +  +  ++     e+L + i+kd+  a +++ ++   l  + +++ l+
  EEA21920.1 272 SFR--NEILKLILELLNQIPSpdyfAIAKcvVYLDEHSMATEILRQLIDKDETRARTIAYQISFDLYDNSTQEFLK 345
                 333..34555555555555544444222223444555555667777777777777777777776666666666555 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 3.9
        Cnd1  73 rVvanalaalteisek.senaiynllpdiisklsda 107
                 +  + a++a+t+i +  ++ ++++l+ + +++ ++a
  EEA21920.1 385 ELTEEARLAFTNIRDIlQGVKTIQLNLEFLYRSNKA 420
                 556678888888888877778888888888887754 PP

  == domain 3  score: 6.2 bits;  conditional E-value: 0.0047
        Cnd1  26 LrkrLkDedpyVRktaaivvakLilndmvkekgflselaklleDenprVvanalaalteiseks 89 
                 ++  L D+dpy R   +++va L   ++  +k + + l  +++D n+ V+  a+++l  i+ ++
  EEA21920.1 646 INGLLGDPDPYLRYGGIMTVA-LAYCGTGSNKAVRKLLHVAVSDVNDDVRRVAVMSLGFILFRK 708
                 556688999999999998887.667777777777788888889999999999999988777665 PP

  == domain 4  score: 15.6 bits;  conditional E-value: 6.4e-06
        Cnd1   2 iRalairtlgcirvpnlveylvepLrkrLkDedpyVRktaaivvakL..ilnd.mvkekg.flselaklleDenpr 73 
                 +R  a ++lg  +  + +++ ++ L+  LkD+   VR+ a+i +a +   +n+ m  + g + ++++k+++D ++ 
  EEA21920.1 727 VRYGAAMALGISCAGTGLDEAIDLLEPMLKDPTDFVRQGALISLAMVlvQQNEtMNPKVGsIRKMMNKMITDRHED 802
                 77788899999999999*****************************9864444255455557788999**998876 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.0     0.015        30       7      43 ..      42      80 ..      38      92 .. 0.80
   2 ?    4.8   0.0     0.017        33      25      69 ..     292     335 ..     278     342 .. 0.87

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.015
                HHHHHHHHHH...HHH--HHHHHHHHHHHHHTT-HHHHH CS
      ANAPC3  7 nAiflaerlla..aetespedayllAlclylngqykrAy 43
                +Ai  +e l++  + +e++ +a+  ++++y++++y++ +
  EEA21920.1 42 DAIPQIEALYEdeTFPERELAALVASKVYYHLQEYNESM 80
                7888999999644778999999999*********99866 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.017
                 HHHHHHHHHHHTT-HHHHHHHHHCTSHHHC-HHHHHHHHHHHHHT CS
      ANAPC3  25 dayllAlclylngqykrAyellrkaklnskslgcrylfAqcllkL 69 
                 d ++ A+c   + ++  A e+lr++ +++   ++r ++ q +++L
  EEA21920.1 292 DYFAIAKCVVYLDEHSMATEILRQL-IDKDETRARTIAYQISFDL 335
                 67889********************.77778899*******9999 PP

>> HEAT_PBS  PBS lyase HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.2       2.6   5.2e+03       8      25 ..     632     649 ..     627     650 .. 0.81
   2 ?   -0.6   0.0       1.6   3.1e+03       1      12 [.     693     704 ..     693     704 .. 0.92
   3 ?   10.2   0.0   0.00052         1       1      27 []     727     757 ..     727     757 .. 0.96

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 2.6
                 HHHHCTSGGGHHHHHHHC CS
    HEAT_PBS   8 aLgqlgdeeaipaLleaL 25 
                 aL   g +ea++ L++ L
  EEA21920.1 632 ALIMYGRQEAADELINGL 649
                 66777889******9987 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 1.6
                 HHHHHHHHHHHC CS
    HEAT_PBS   1 vRraAakaLgql 12 
                 vRr A+ +Lg +
  EEA21920.1 693 VRRVAVMSLGFI 704
                 9*********76 PP

  == domain 3  score: 10.2 bits;  conditional E-value: 0.00052
                 HHHHHHHHHHHCTS....GGGHHHHHHHCTC CS
    HEAT_PBS   1 vRraAakaLgqlgd....eeaipaLleaLqd 27 
                 vR+ Aa aLg   +    +eai++L   L+d
  EEA21920.1 727 VRYGAAMALGISCAgtglDEAIDLLEPMLKD 757
                 9************************999987 PP

>> Clathrin_H_link  Clathrin-H-link
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.1   0.00052         1       9      40 ..     202     234 ..     198     247 .. 0.90
   2 ?   -1.8   0.0       1.6   3.1e+03      19      44 ..     383     408 ..     373     409 .. 0.84
   3 ?   -2.7   0.1       2.9   5.9e+03      20      34 ..    1058    1072 ..    1047    1073 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00052
  Clathrin_H_link   9 yvqqFeqllaqgnykeAakvAaespq.giLRtp 40 
                      + + Feq+++q++y++ + +A e+++ ++LRt+
       EEA21920.1 202 IERLFEQCFRQQRYRQVVGIAIEAKNlDVLRTA 234
                      5678*******************9986899995 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 1.6
  Clathrin_H_link  19 qgnykeAakvAaespqgiLRtpetIq 44 
                      + +  e a++A ++ ++iL   +tIq
       EEA21920.1 383 KAELTEEARLAFTNIRDILQGVKTIQ 408
                      56677889***********9999998 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 2.9
  Clathrin_H_link   20 gnykeAakvAaespq 34  
                        + + Aa+ A e+pq
       EEA21920.1 1058 IQAQGAANAAFETPQ 1072
                       467888888888887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1118 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1382  (0.0770818); expected 358.6 (0.02)
Passed bias filter:                      678  (0.0378158); expected 358.6 (0.02)
Passed Vit filter:                        71  (0.00396006); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.83u 0.29s 00:00:01.11 Elapsed: 00:00:00.41
# Mc/sec: 8160.65
//
Query:       EEA21921.1  [L=484]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
     0.0033   18.0   5.0     0.0033   18.0   5.0    3.0  3  BST2          Bone marrow stromal antigen 2
  ------ inclusion threshold ------
       0.19   11.4   5.0       0.42   10.3   1.5    2.2  2  RPW8          Arabidopsis broad-spectrum mildew resistance pr
       0.22   11.3   9.4        4.9    6.9   3.9    2.7  2  Phage_GP20    Phage minor structural protein GP20
       0.37   11.4   4.9        7.1    7.3   0.2    3.8  2  Syntaxin-6_N  Syntaxin 6, N-terminal


Domain annotation for each model (and alignments):
>> BST2  Bone marrow stromal antigen 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   5.0   7.4e-07    0.0033      17      88 ..     123     195 ..     119     198 .. 0.85
   2 ?   -2.7   0.2         2     9e+03      53      78 ..     262     287 ..     256     289 .. 0.53
   3 ?    1.1   0.8      0.13     6e+02      56      87 ..     328     360 ..     297     362 .. 0.74

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 7.4e-07
                 HHHHHHHHHHHHHHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        BST2  17 nvtrlLerqLtqaqeslreaeaqa...atcnqtvvtLkasLekekaqsqkqqakvqelqgeikkLnqkLqdaeae 88 
                 + +rlL+rq++q qe ++e ++ a   a  ++t+ +L+++ e ++a++ k   +++ l+ ei++L+ kL d +a 
  EEA21921.1 123 EEKRLLQRQIQQRQEAIEEVDTFAskkAGLEKTLTDLENDREGDRARKLKG--EAKGLEYEIEELELKLADMKAR 195
                 679**************999875522277899*******999999997766..8899************998875 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 2
                 HHHHHHHHHHHHHHHHHHHHHHHHHH CS
        BST2  53 sLekekaqsqkqqakvqelqgeikkL 78 
                 + e+ +a++ +  ++ +    ei+ L
  EEA21921.1 262 AREHWQAEQSELAKRQESVDMEIAAL 287
                 44555555555555555555666555 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.13
                 HHHHHHHHHHHH.HHHHHHHHHHHHHHHHHHHH CS
        BST2  56 kekaqsqkqqak.vqelqgeikkLnqkLqdaea 87 
                 +e+a++q+q +k +++l+   + +++kL+ ae+
  EEA21921.1 328 NEEARKQEQGKKiIEDLEATTRFIEEKLELAEE 360
                 455666666544268888888888888877665 PP

>> RPW8  Arabidopsis broad-spectrum mildew resistance protein RPW8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   1.5   9.5e-05      0.42      22     113 ..     137     234 ..     127     247 .. 0.87
   2 ?    2.2   0.1     0.029   1.3e+02      62     129 ..     298     369 ..     273     379 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 9.5e-05
        RPW8  22 eakkksldfksilkrLestleritPvvk..eieklnkeldrpreeieeLkklLekae....kLVekcsklkrynvlkkyrYkkklkeLekslrkfvqv 113
                 ea +++ +f+s+   Le+tl++++  ++  +  kl+ e +  + eieeL+ +L + +    +++++ s++     +k  +Yk  l  L+ ++r++ ++
  EEA21921.1 137 EAIEEVDTFASKKAGLEKTLTDLENDREgdRARKLKGEAKGLEYEIEELELKLADMKarhrHIIQEVSRIENAVDAKLSSYKESLSILDTEVRRYLEI 234
                 77888999***************9987433899*****************999754322338********************************9987 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.029
        RPW8  62 reeieeLkklLekaek...LVekcsklk.rynvlkkyrYkkklke.Lekslrkfvqvelqvqqvrdikellak 129
                  +e+  ++++L+++ +   +++k+s l    + ++k    kk++e Le+ + +f++ +l++ + +d k l+ +
  EEA21921.1 298 VKELSGFERRLRDGMQqslMLSKSSLLPsDNEEARKQEQGKKIIEdLEA-TTRFIEEKLELAEEKDWKLLVCS 369
                 5677777777777754444677777777555567777777776651555.56789999999999998877665 PP

>> Phage_GP20  Phage minor structural protein GP20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   3.9    0.0011       4.9      24      66 ..     122     164 ..     108     172 .. 0.89
   2 ?    6.3   0.5    0.0017       7.8      48      93 ..     172     218 ..     166     222 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0011
  Phage_GP20  24 eeerdtlkeqlkdrdkqLedLkkkakdneeLqkqieelqaknk 66 
                 eee+  l+ q+++r++ +e+  + a   + L+k++++l+++ +
  EEA21921.1 122 EEEKRLLQRQIQQRQEAIEEVDTFASKKAGLEKTLTDLENDRE 164
                 6788899*******************************99865 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0017
  Phage_GP20  48 akdneeLqkqieelqaknkkakaeyeakiadlk.ldnaielaLkeak 93 
                 +++++ L+ +ieel+ k+++ ka +   i+++  ++na++  L+ +k
  EEA21921.1 172 KGEAKGLEYEIEELELKLADMKARHRHIIQEVSrIENAVDAKLSSYK 218
                 456888999********************998537999999998877 PP

>> Syntaxin-6_N  Syntaxin 6, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   0.2    0.0016       7.1      35      86 ..     199     278 ..     105     285 .. 0.55
   2 ?    1.0   0.7      0.14   6.4e+02      34      58 ..     332     356 ..     295     413 .. 0.72

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0016
  Syntaxin-6_N  35 tseeldetrteLrkalrsiewdledLeetv............................riveknpskfkidekelsrrra 86 
                     +e+++ ++ + ++l+s ++ l+ L+  v                            r++e  +++ + +++el++r++
    EEA21921.1 199 IIQEVSRIENAVDAKLSSYKESLSILDTEVrryleipplqplkhnvkrssfyslhpkrRTLELAREHWQAEQSELAKRQE 278
                   34455555555555555555555555555555555555555555555555555555555555566666666666666665 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.14
  Syntaxin-6_N  34 stseeldetrteLrkalrsiewdle 58 
                   +++e+ ++  ++L+++ r ie++le
    EEA21921.1 332 RKQEQGKKIIEDLEATTRFIEEKLE 356
                   3444445555555555555555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (484 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1218  (0.0679346); expected 358.6 (0.02)
Passed bias filter:                      494  (0.0275531); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.65u 0.32s 00:00:00.97 Elapsed: 00:00:00.48
# Mc/sec: 3025.07
//
Query:       EEA21922.1  [L=386]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0082   16.8   4.8      0.021   15.5   4.8    1.7  1  RCR       Chitin synthesis regulation, resistance to Congo re
  ------ inclusion threshold ------
      0.054   12.6   0.5      0.082   12.0   0.5    1.2  1  TAS2R     Taste receptor protein (TAS2R)
      0.084   12.8   0.2       0.19   11.6   0.0    1.6  2  TMEM154   TMEM154 protein family
        0.1   13.5   0.0       0.17   12.8   0.0    1.4  1  EphA2_TM  Ephrin type-A receptor 2 transmembrane domain


Domain annotation for each model (and alignments):
>> RCR  Chitin synthesis regulation, resistance to Congo red
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   4.8   4.6e-06     0.021       5     118 ..     234     383 ..     228     384 .. 0.54

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 4.6e-06
         RCR   5 faiiivlillvllltlrvakrRrrrGlqplygtgWlvs...a.pppPsYgqsqqqynqa...........esltsatvptytpnane...edaGyydqe 85 
                  ++iiv+ l++  ++l+  +r+  + ++  +  +W+++   + p  P ++ s+   +q+            s+++     ++  +++   ++aGy+   
  EEA21922.1 234 GFLIIVASLALCCFCLVRHRRKIAKKRRNQMQNRWMQPawgGyPVSPYHQASPMMLQQQymmaggmgpygASVPGR---GFSVVDHDgkrYEAGYST-- 327
                 344555555555555557777777888899999***8765425666666666665555555555453332112222...244333222236666655.. PP

         RCR  86 Gkfhe...........................lqqPqqayqreesaeeseaeyqpPagpp 118
                     +                           ++qP  ++++   + ++ +ey pP+g p
  EEA21922.1 328 ----HyispvspedtvaqqpfqfgtdvthaqdVKQPIPQQTEYPPPPQTTQEYYPPPGAP 383
                 ....13444556666655556666665566664444433333334444588899998877 PP

>> TAS2R  Taste receptor protein (TAS2R)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.5   1.8e-05     0.082     170     219 ..     212     261 ..     186     268 .. 0.65

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 1.8e-05
       TAS2R 170 klkeeklellsslvllnlgvllpfivflisflLLivSLwrHtkkmqlnst 219
                  ++   +++ ++l+++ ++ ++ f+++++s+ L  + L+rH +k+ ++++
  EEA21922.1 212 ATSTGTSTVQQFLTVIIVMPIIGFLIIVASLALCCFCLVRHRRKIAKKRR 261
                 22223333333333334677888999999****************98765 PP

>> TMEM154  TMEM154 protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.0       2.6   1.2e+04      20      35 ..      29      44 ..      20      56 .. 0.61
   2 ?   11.6   0.0   4.2e-05      0.19      17      91 ..     185     259 ..     176     268 .. 0.50

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 2.6
     TMEM154 20 esadatsaastesesl 35
                 +   +++++t+s+ +
  EEA21922.1 29 CTDVCGTTTNTTSDEM 44
                5555566666666554 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 4.2e-05
     TMEM154  17 leeesadatsaasteseslkqeeakeslssaelsnesdqlel.vlmiiiPlvllill..llvviiliqkkkrkrsKdd 91 
                  +++ + at + +t    l+ +++   +s a    +s  +++  ++i++P + ++++  +l+ + +  + +r+++  +
  EEA21922.1 185 GTSFPIAATRIFNT--THLP-TTTVSYTSTATSTGTSTVQQFlTVIIVMPIIGFLIIvaSLALCCFCLVRHRRKIAKK 259
                 45555566666666..4455.333333444444445554444256667788866655114555555544444433333 PP

>> EphA2_TM  Ephrin type-A receptor 2 transmembrane domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   3.7e-05      0.17       2      37 ..     228     270 ..     227     339 .. 0.60

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 3.7e-05
    EphA2_TM   2 iaaavaglvllvilvilvlvlvrrrsknrkqksdl.......k 37 
                 i++ ++g++++v+ ++l+ +++ r++++ ++k+++       +
  EEA21922.1 228 IVMPIIGFLIIVASLALCCFCLVRHRRKIAKKRRNqmqnrwmQ 270
                 6666777777777666666655555555444444324444440 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (386 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1039  (0.0579508); expected 358.6 (0.02)
Passed bias filter:                      573  (0.0319594); expected 358.6 (0.02)
Passed Vit filter:                        74  (0.00412739); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.22s 00:00:00.74 Elapsed: 00:00:00.38
# Mc/sec: 3059.12
//
Query:       EEA21923.1  [L=328]
Description: hypothetical protein PMAA_057120 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        6.2    7.9   8.9        2.5    9.1   3.0    2.3  2  Spt5_N    Spt5 transcription elongation factor, acidic N-term


Domain annotation for each model (and alignments):
>> Spt5_N  Spt5 transcription elongation factor, acidic N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.3      0.03   5.3e+02      53      82 ..      91     121 ..      71     132 .. 0.60
   2 ?    9.1   3.0   0.00014       2.5      11      83 ..     144     218 ..     137     228 .. 0.63

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.03
                 XXXXXXXX.XXXXXXXXXXXXXXXXXXXXXX CS
      Spt5_N  53 rrrqaeed.edaeeiaealeeRYgrsskkay 82 
                 r+ + +++ ++    +++++eR+ r+++ + 
  EEA21923.1  91 RHPMVDMQaRKRSISVDRIKERHDRQRSVSR 121
                 4444444434444556778888877655443 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.00014
                 XX.XXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXXXXX CS
      Spt5_N  11 de.eeeeeeeeveggeddfiaeeeaeeeeedserddrshreldrrrqaeededae...eiaealeeRYgrsskkayr 83 
                 ++ ee     e +  e  +i++++ +   +++e+  r++++ +rr+ +++++++      a a  +RY ++s+++ r
  EEA21923.1 144 EDgEELPNHAEFDHRER-DIERRNVPSRSNSQEDYWRAQSRNNRRDSQQSSMQLKsppLSATAVMRRYSSQSEST-R 218
                 22233333333333333.57887777777778888888888888888888866662326899******9865443.3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (328 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       948  (0.0528752); expected 358.6 (0.02)
Passed bias filter:                      352  (0.019633); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2286.75
//
Query:       EEA21924.1  [L=275]
Description: hypothetical protein PMAA_057130 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    0.00012   21.4   3.3    0.00025   20.4   3.3    1.5  1  SKG6             Transmembrane alpha-helix domain
  ------ inclusion threshold ------
      0.013   15.3   4.4      0.043   13.6   4.4    1.9  1  Trp_oprn_chp     Tryptophan-associated transmembrane protein 
      0.017   14.9   0.2      0.085   12.7   0.0    2.2  2  Mid2             Mid2 like cell wall stress sensor
       0.04   14.0   0.2      0.069   13.2   0.2    1.3  1  Peptidase_S49_N  Peptidase family S49 N-terminal
      0.053   13.6   1.4        0.1   12.7   1.4    1.4  1  Insulin_TMD      Insulin receptor trans-membrane segment
      0.071   14.1   0.8      0.071   14.1   0.8    2.4  2  DUF4834          Domain of unknown function (DUF4834)
       0.11   12.2   3.0       0.31   10.8   3.0    1.8  1  DUF3188          Protein of unknown function (DUF3188)
       0.11   12.2   0.0       0.21   11.4   0.0    1.4  1  Herpes_UL92      UL92 family
       0.13   12.2   1.4       0.25   11.3   1.4    1.4  1  Gram_pos_anchor  LPXTG cell wall anchor motif
       0.14   11.5   0.0       0.25   10.7   0.0    1.3  1  DUF5305          Family of unknown function (DUF5305)
       0.34   11.1   5.3        4.4    7.6   5.3    2.1  1  TrbC             TrbC/VIRB2 family
       0.72   10.6   5.3       0.57   10.9   1.7    2.2  2  U3_snoRNA_assoc  U3 snoRNA associated
       0.77   10.7   5.4        2.8    8.9   3.5    2.7  2  EphA2_TM         Ephrin type-A receptor 2 transmembrane domai
       0.83    9.7   4.1       0.37   10.9   0.2    2.2  3  Podoplanin       Podoplanin
        1.2    9.7   3.1        2.7    8.6   0.8    2.1  2  Porph_ging       Protein of unknown function (Porph_ging)
        2.6    8.3   5.3         80    3.5   5.3    2.5  1  HemY_N           HemY protein N-terminus
        4.6    7.8   5.4         11    6.6   5.4    1.8  1  Ctr              Ctr copper transporter family


Domain annotation for each model (and alignments):
>> SKG6  Transmembrane alpha-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   3.3   2.4e-07   0.00025       6      38 .]      63      95 ..      60      95 .. 0.93

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 2.4e-07
        SKG6  6 nsntvaIavaVaVPVaViiivLlailifvrRRk 38
                +s+ + I+++V+++V+    +++ai +f rR+k
  EEA21924.1 63 LSKLAQIVIGVVIGVIGLGTIVGAIVFFFRRKK 95
                678899*************************97 PP

>> Trp_oprn_chp  Tryptophan-associated transmembrane protein (Trp_oprn_chp)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   4.4   4.1e-05     0.043      73     164 ..      18     123 ..      10     158 .. 0.60

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 4.1e-05
  Trp_oprn_chp  73 llalagagaavaalslltdpadaaraaaaaatgvasaaaavelta.............wpvlalaggvllllagvllllrarswpamssrYerpaar 156
                    l+++ ++a+v+a s   ++a   + a+  +t+ ++a a+    +             ++v+ ++g   ++ a v+ ++r+++w ++ +rYe+ +a 
    EEA21924.1  18 ALVVSCLAATVQANSSSGTDAPGTNPASGPTTAYNEAGAS----GnngglsklaqiviGVVIGVIGLGTIVGAIVFFFRRKKKWDEKIKRYETINAY 110
                   2222222222222222222222222222222222222222....1333344477788799999999999999999999***************9996 PP

  Trp_oprn_chp 157 raeaeae.....d 164
                    ++++++     +
    EEA21924.1 111 HNAQREAkrqqaM 123
                   5555544334452 PP

>> Mid2  Mid2 like cell wall stress sensor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0     8e-05     0.085      30      76 ..      51      96 ..      30     137 .. 0.73
   2 ?   -1.1   0.3       1.5   1.6e+03      16      43 ..     236     263 ..     229     266 .. 0.67

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 8e-05
        Mid2 30 aessnk.skssGLskknrniviGcvvGigvPlllvillllyifCiksk 76
                 ++     ++ GLsk   +iviG+v+G+ + l  ++ +++++f  k+k
  EEA21924.1 51 YNEAGAsGNNGGLSK-LAQIVIGVVIGV-IGLGTIVGAIVFFFRRKKK 96
                333333256667775.678********7.5666777788887765555 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 1.5
        Mid2  16 sdlyttvtytptataessnkskssGLsk 43 
                 s++   v  ++ a a+s+n+ k +GL k
  EEA21924.1 236 SNSEQSVNDSSDAQASSNNQGKLKGLKK 263
                 5666666667777777777777777755 PP

>> Peptidase_S49_N  Peptidase family S49 N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.2   6.6e-05     0.069      10      79 ..      70     140 ..      62     159 .. 0.66

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 6.6e-05
  Peptidase_S49_N  10 laklvtlvvailvvvvlivalaakkkkekgelevtkLneeykelkeele.ealldeeelkaaekkekkeek 79 
                      +  +v+ v+ + ++v++iv + ++kkk +++++  +  + y++ ++e + ++ +++++++++++++++++ 
       EEA21924.1  70 VIGVVIGVIGLGTIVGAIVFFFRRKKKWDEKIKRYETINAYHNAQREAKrQQAMSNRQQRQRRQRQQERDA 140
                      44566677778889999999999999999999877666666666666651555666555554444443333 PP

>> Insulin_TMD  Insulin receptor trans-membrane segment
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   1.4   9.6e-05       0.1      12      42 ..      64      95 ..      61      98 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 9.6e-05
  Insulin_TMD 12 snivkIvigPviciillllvigavfvvv.kKr 42
                 s++++Ivig vi +i l  ++ga+  ++ +K+
   EEA21924.1 64 SKLAQIVIGVVIGVIGLGTIVGAIVFFFrRKK 95
                 6789***********88877776655550555 PP

>> DUF4834  Domain of unknown function (DUF4834)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.8   6.7e-05     0.071      11      77 ..      69     136 ..      63     157 .. 0.48
   2 ?    1.9   0.3      0.42   4.4e+02      49      72 ..     225     248 ..     189     265 .. 0.46

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 6.7e-05
     DUF4834  11 iiailviglsilsvilrtvfglgsrkkss.ksaqkqfgnstnsnqqksqsrsetkeegeiieeersek 77 
                 i++ +vig++ l++i+ ++  + +rkk+  ++ ++ ++ +  +n+q++ +r++  ++ +  ++++ ++
  EEA21924.1  69 IVIGVVIGVIGLGTIVGAIVFFFRRKKKWdEKIKRYETINAYHNAQREAKRQQAMSNRQQRQRRQRQQ 136
                 67778888888888887774433333333233333333333333333322222222221111111111 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.42
     DUF4834  49 stnsnqqksqsrsetkeegeiiee 72 
                 ++++ +++ ++++++++ +++ + 
  EEA21924.1 225 GFGGYSAQVTTSNSEQSVNDSSDA 248
                 222222222211111111111111 PP

>> DUF3188  Protein of unknown function (DUF3188)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   3.0   0.00029      0.31      29      50 .]      75      96 ..      61      96 .. 0.94

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00029
     DUF3188 29 allvGlgLivsgavgrgrrrrk 50
                ++++Glg iv  +v+++rr++k
  EEA21924.1 75 IGVIGLGTIVGAIVFFFRRKKK 96
                789*****************98 PP

>> Herpes_UL92  UL92 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0    0.0002      0.21     142     183 ..      62     103 ..      53     112 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.0002
  Herpes_UL92 142 gydvicslyiqviisiyskktvYdallfkvtknKryDsvlKk 183
                  g++ ++++ i v+i++    t+ +a++f   ++K++D  +K+
   EEA21924.1  62 GLSKLAQIVIGVVIGVIGLGTIVGAIVFFFRRKKKWDEKIKR 103
                  67778999*****************************99998 PP

>> Gram_pos_anchor  LPXTG cell wall anchor motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   1.4   0.00024      0.25      22      41 ..      77      96 ..      73      96 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00024
                     XXXXXXXXXXXXXXXXXXXX CS
  Gram_pos_anchor 22 aaGllallggllLlvkrRKk 41
                     + Gl  ++g+++++++r+Kk
       EEA21924.1 77 VIGLGTIVGAIVFFFRRKKK 96
                     7899***************7 PP

>> DUF5305  Family of unknown function (DUF5305)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00024      0.25     113     157 ..      66     110 ..      40     113 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00024
     DUF5305 113 laegilliilgllaliglvvlirriiftsskaekyelelekilke 157
                 la++++++++g+++l+ +v +i++ +  ++k +++ +++e i   
  EEA21924.1  66 LAQIVIGVVIGVIGLGTIVGAIVFFFRRKKKWDEKIKRYETINAY 110
                 334999******************888888889999998887655 PP

>> TrbC  TrbC/VIRB2 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   5.3    0.0042       4.4      14      77 ..      14      98 ..       1     102 [. 0.75

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0042
        TrbC 14 alalalvllllaspalAqaagg.....................dpvetvlqnivdfltgplakviatiaiivaGimlafgrls.wr 77
                +la+alv+ +la ++ A +++g                     +  ++ l ++ + + g ++++++ ++ iv +i+++f+r+  w+
  EEA21924.1 14 LLACALVVSCLAATVQANSSSGtdapgtnpasgpttayneagaSGNNGGLSKLAQIVIG-VVIGVIGLGTIVGAIVFFFRRKKkWD 98
                555666666666666665555566666666666666666666789999***********.********************998665 PP

>> U3_snoRNA_assoc  U3 snoRNA associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   1.7   0.00054      0.57      28      76 ..     108     163 ..      90     172 .. 0.77
   2 ?    0.6   0.1      0.87   9.2e+02      28      50 ..     235     265 ..     201     270 .. 0.53

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00054
  U3_snoRNA_assoc  28 n......eepkkarkkkkkekllelkekrpkdvkkGpvsvrVlkssnss.klaPka 76 
                      n      +e+k+++  +++++++ +++++++d+ +G   ++ l  ++ + +++P  
       EEA21924.1 108 NayhnaqREAKRQQAMSNRQQRQRRQRQQERDAEQGMLEISTLPRDQTRdSVVPSY 163
                      23334568888889999999999999*****************9998888999975 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.87
  U3_snoRNA_assoc  28 n........eepkkarkkkkkekllelkekr 50 
                      +        + + ++  ++++ kl+ lk+ +
       EEA21924.1 235 TsnseqsvnDSSDAQASSNNQGKLKGLKKPK 265
                      0222222324445555555555555555444 PP

>> EphA2_TM  Ephrin type-A receptor 2 transmembrane domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   3.5    0.0026       2.8       1      38 [.      69     121 ..      69     181 .. 0.68
   2 ?   -2.3   0.0       7.9   8.4e+03      29      29 ..     237     237 ..     192     262 .. 0.57

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0026
    EphA2_TM   1 iiaaavaglvllvilvilvlvlvrrrsknrkqksdl.........k......s 38 
                 i++++v+g++ l ++v  +++++rr++k +++ ++          +      +
  EEA21924.1  69 IVIGVVIGVIGLGTIVGAIVFFFRRKKKWDEKIKRYetinayhnaQreakrqQ 121
                 67788888888888777666666555555555444445554443303332220 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 7.9
    EphA2_TM  29 n 29 
                 n
  EEA21924.1 237 N 237
                 0 PP

>> Podoplanin  Podoplanin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.2   0.00035      0.37      90     154 ..      28      93 ..      15      97 .. 0.54
   2 ?   -3.0   0.0       6.3   6.7e+03      95     111 ..     112     128 ..      98     151 .. 0.44
   3 ?   -0.9   0.1       1.5   1.5e+03     103     117 ..     232     246 ..     214     263 .. 0.53

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00035
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX...X.XXXXXXXXXXX CS
  Podoplanin  90 vkakeesqstttlnvvtshstekvgeetettvekdGLatvtLvgiivGvllai...g.figgiiivvvr 154
                 v+a+  s + +     +s +  ++ +e   + +++GL+   L  i++Gv++++   g ++g i++ + r
  EEA21924.1  28 VQANSSSGTDAPGTNPASGP-TTAYNEAGASGNNGGLSK--LAQIVIGVVIGViglGtIVGAIVFFFRR 93 
                 44443333322222222223.56777888888999*986..4555555555431114144555555444 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 6.3
                 XXXXXXXXXXXXXXXXX CS
  Podoplanin  95 esqstttlnvvtshste 111
                 ++q  + ++ + s+ ++
  EEA21924.1 112 NAQREAKRQQAMSNRQQ 128
                 33333333333333332 PP

  == domain 3  score: -0.9 bits;  conditional E-value: 1.5
                 XXXXXXXXXXXXXXX CS
  Podoplanin 103 nvvtshstekvgeet 117
                 +v ts+s + v+++ 
  EEA21924.1 232 QVTTSNSEQSVNDSS 246
                 333333333333322 PP

>> Porph_ging  Protein of unknown function (Porph_ging)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.8    0.0025       2.7       9      49 ..     100     140 ..      95     169 .. 0.80
   2 ?    0.9   0.1      0.66   6.9e+02       7      42 ..     220     255 ..     217     269 .. 0.64

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0025
  Porph_ging   9 qIgqYtcfkAtavkeveetdfsnlrrrerreeekkekeeee 49 
                 +I +Y+ + A    + e ++ +++++r++r+++++++e++ 
  EEA21924.1 100 KIKRYETINAYHNAQREAKRQQAMSNRQQRQRRQRQQERDA 140
                 8999******9999999999999888888877777665333 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.66
  Porph_ging   7 tkqIgqYtcfkAtavkeveetdfsnlrrrerreeek 42 
                 +k+  ++  + A+++++ +e++++++++++++++++
  EEA21924.1 220 SKRYKGFGGYSAQVTTSNSEQSVNDSSDAQASSNNQ 255
                 556666667777788887777777777655544443 PP

>> HemY_N  HemY protein N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   5.3     0.076        80      17      69 ..      67     146 ..      64     149 .. 0.64

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.076
      HemY_N  17 vvavlllvllfvllylllrllrlllrl...........................parvrrwrrrrrerkarealseGlia 69 
                  + v+ +v++++ l  ++ ++ +++r                             a ++r +r+rr+r+ ++  ++G+++
  EEA21924.1  67 AQIVIGVVIGVIGLGTIVGAIVFFFRRkkkwdekikryetinayhnaqreakrqQAMSNRQQRQRRQRQQERDAEQGMLE 146
                 56666666666666666666666666666666666665555555555555555455666778888888888888888876 PP

>> Ctr  Ctr copper transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   5.4     0.011        11      25      84 ..      71     166 ..      64     271 .. 0.64

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.011
         Ctr  25 agsciglfllaifyeflralrerlerewdrhla...........rsrekrkaassplvdssssseeeaea..........................k 84 
                 +g +ig++ l  ++ ++  + +r +++wd++++           +++ kr++a s+++++++++++++++                          +
  EEA21924.1  71 IGVVIGVIGLGTIVGAIV-FFFRRKKKWDEKIKryetinayhnaQREAKRQQAMSNRQQRQRRQRQQERDaeqgmleistlprdqtrdsvvpsydpS 166
                 566667766666666666.445556678888843444555555422224444444444333333333333566777666666665555544444440 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2144  (0.119583); expected 358.6 (0.02)
Passed bias filter:                      911  (0.0508115); expected 358.6 (0.02)
Passed Vit filter:                       141  (0.00786435); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              17  [number of targets reported over threshold]
# CPU time: 0.57u 0.33s 00:00:00.89 Elapsed: 00:00:00.44
# Mc/sec: 1896.03
//
Query:       EEA21925.1  [L=409]
Description: mannose-6-phosphate isomerase, class I [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.5e-63  214.5   0.0      2e-61  208.3   0.0    2.0  1  PMI_typeI  Phosphomannose isomerase type I


Domain annotation for each model (and alignments):
>> PMI_typeI  Phosphomannose isomerase type I
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  208.3   0.0   1.1e-65     2e-61       2     370 ..       7     368 ..       6     371 .. 0.85

  Alignments for each domain:
  == domain 1  score: 208.3 bits;  conditional E-value: 1.1e-65
                 EEEEEEEEE-TTBEECGGSHHHHHHHHH-TT......TTSCEEEEEEC--TTS-EECTTTC..CCCHCHHHHHHHTGHHHCCHHTSS-SEEEEEEEESS CS
   PMI_typeI   2 fkLqcgvqnyaWGkiGsesalakllaasdPs....ieedkpyaElWmgtHpkgpskvlnkk..lkdvvlkellaelresvgkkfgeelpfLfKvLsvek 94 
                   L+c+ +   WGk+G e +la +la+++P     i+ +++y+E+Wmgt p++ps v+ ++  l+d  +k+  ++ ++++ +kfg+ lpfL K+Ls+ k
  EEA21925.1   7 VELRCKCKTDPWGKKG-EDSLAAVLASKQPGtdfkIDPNQTYSEMWMGTYPSVPSFVIGTDetLEDYLNKN-PNLVGKKIVDKFGGGLPFLPKILSMDK 103
                 5799************.999**********99999*********************998887799998888.7899*********************** PP

                 ---EEE---HHHHHHHHHH.TCCCHCCCTTTEEEEESS.EEEEEEE..HHHHHHHCCCEHCCHCCCECCHHCCHHHHHHCCHTTSHHHHCCCCHHCCHC CS
   PMI_typeI  95 vlSiqvHPdKklaeilhaadpknYpddNhkpElaiAltdFeglcgfrpleeiveflkkvselaeligeetaksleelvslieagdpealkkkkvlqklF 193
                 +l +q+HPd+kl+e lh + p+++ d  hkpE+aiAl +Fe ++g++pl+++++   +  +l++ +   +++  +e                  l+++ 
  EEA21925.1 104 ALPLQIHPDRKLSESLHRQLPQKFTDTTHKPEIAIALSQFELFAGWKPLNDLTRLFRN-GPLNKFLPTPESHFNDE-----------------TLKQIG 184
                 **************************************************99886664.45555444333222222.................244455 PP

                 HCCCTTTHHCCCHCCCCCCCCCCC-HHHCCCC-HHHHCCHCHHHSTT.TTC.HCH.TTEEEEEE.TT.EECCHCCHHCECCEEEEEEEEES-EEEEECC CS
   PMI_typeI 194 ssllnsekekikqklallveriqssdaevnktdlaelidrlneqyPd.diG.lfa.llLNlvkLnpGEAmflkandphaylsGdivecmaasdnvvRaG 289
                  ++l+++++ +    ++l ++ +s  +++  +  +++++r++ qy + d+G lfa + +N++ L++GEA+++  +  haylsG+i+ecma sdnv+  G
  EEA21925.1 185 QNMLEADERTVADTIRQLTKTPESAFGKYSYI--PKMLERVSAQYSEyDNGtLFAvVCMNYLVLQNGEAVYVPTDGMHAYLSGNIMECMARSDNVLNTG 281
                 56789999999999999999999888777666..8**********9778994567999***************************************** PP

                 CECCE..EECHCCHCH.EEEEEECCCCEE--BS..CEECE...EEEEEECCCCECCEEECCC.TTEEEEE-TTS-EEEEEEECEEEEEE CS
   PMI_typeI 290 lTpKf..idvkelvemltYkykpsdelklqqte..sllda...svlydppieefavektklk.kgeatilplesasiliaveGtatiiv 370
                 + p+     v  ++e  t   +  de+ l ++           +v y ppi ef+v  t+lk + +++++p e++si+ ++ G++++++
  EEA21925.1 282 FCPRPgrDSVALFCEAFTGWPQDPDEARLGKHIsnRG--LngkTVEYAPPISEFNVLATHLKaGEKEKMSPIEGPSIICVTGGEGRMMA 368
                 **99521456677885554334448888887774423..24469999***************666789****************99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (409 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       431  (0.0240393); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.32s 00:00:00.90 Elapsed: 00:00:00.50
# Mc/sec: 2462.29
//
Query:       EEA21926.1  [L=331]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (331 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       979  (0.0546043); expected 358.6 (0.02)
Passed bias filter:                      441  (0.024597); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.47
# Mc/sec: 2127.99
//
Query:       EEA21927.1  [L=1009]
Description: beta galactosidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      2e-86  290.5   2.0    3.8e-86  289.6   2.0    1.4  1  Glyco_hydro_35  Glycosyl hydrolases family 35
    4.3e-59  198.1   5.9    2.3e-34  118.4   0.1    3.0  3  BetaGal_dom4_5  Beta-galactosidase jelly roll domain
    1.6e-55  187.7   0.2    2.7e-55  187.0   0.2    1.4  1  BetaGal_dom2    Beta-galactosidase, domain 2
    6.4e-25   86.5   0.0    1.7e-24   85.1   0.0    1.8  1  BetaGal_dom3    Beta-galactosidase, domain 3
    1.1e-06   28.3   0.3      2e-06   27.4   0.3    1.4  1  Cellulase       Cellulase (glycosyl hydrolase family 5)


Domain annotation for each model (and alignments):
>> Glyco_hydro_35  Glycosyl hydrolases family 35
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  289.6   2.0   1.1e-89   3.8e-86       1     312 [.      41     388 ..      41     391 .. 0.83

  Alignments for each domain:
  == domain 1  score: 289.6 bits;  conditional E-value: 1.1e-89
                     SEEETTEEE-EEEEEE-GGGS-.GGGHHHHHHHHHHCT-SEEEEE--HHHH-SCTTB---S.GGG-CHHHHHHHHHCT-EEEEEEES---TTBGG CS
  Glyco_hydro_35   1 sllidgerflllsGeihyfRlp.pelWedvlekvkalGlnaietYveWnlhepkegkydfe.GaldlekFlklaqeagLyvilRpGpYicaEwda 93 
                     s+ i+g+r+++++Ge hy+R+p pelW d+lek+ka+G+ a  +Yv+W++h+p++ ++df  Ga+d++  lk+a+++gLyv+lRpGpYi+aE++a
      EEA21927.1  41 SFEINGQRLFVFAGEWHYWRIPvPELWIDILEKIKAAGFTAFGIYVNWAYHAPNNYTVDFAtGAHDITPILKMAKDVGLYVLLRPGPYINAEVNA 135
                     5789********************************************************88********************************* PP

                     GG--GGGGGSTTS-TTSS-HHHHHHCHHHHHHHHHHHHHCBGGGTSSEEEEEESSSGG...........GT---HHHHHHHHHHHCCCT-SSCBE CS
  Glyco_hydro_35  94 GGlpaWllkkkeiklRssdeafleavekyleailkkvkkllltnGGpiilvQvEneYg...........skavdkaylralakalkeklaekall 177
                     GG+p+W ++ ++++lR +d+++++a+e y+++i ++  ++++t+GG+++++Q+Ene+g           ++        + a++++e l+ +a  
      EEA21927.1 136 GGFPLWVTTGEYGSLRNDDSRYTAAWEPYFTKISEIASEYQITKGGNVVTYQIENEFGdqwtgspsrrvQY--------EPAAKYMELLEANARR 222
                     **********************************************************9975544444444........4555555556666666 PP

                     EECESTTTCCCTTS.....STTT.SCEEEEEECTTS.THHHHHHH.......................HHH-TTS--EEEEEESS---BTTS--H CS
  Glyco_hydro_35 178 ftadvpseevaekg.....tlpeedilatvgfgsdakakeafkll.......................kefspekPlvvsefwtgwfdewgekka 244
                     + +d+p ++++++      + ++++  a v++   +  ++ ++                         +e++p+ P++++ef++g +++wg++ +
      EEA21927.1 223 NGIDIPLVANEPNMraiswGKDWSNSSANVDVVGLDSYPSCWTCDlsvctgttgeyiayqvidyygyfQETQPTMPSFFAEFQGGSYNPWGGP-V 316
                     66665555555554211111222222222222222222333333345556666777777788888888*************************.9 PP

                     HHHHHHCCHHHHHHHCCC......SEEEEEECE--B-GCC-B-CCTT.SB--TT-SB-TTS---HHHHHHHHH CS
  Glyco_hydro_35 245 arsaeelaeevervlakn.....issvnlYMihGGTnfGflaganflgtsYdydApldEagnltpkylelkel 312
                       + e++  ++++++++      ++ +nlYM++GGTn+G +a a+++++sYdy +p++E++ + +ky+e k l
      EEA21927.1 317 GGCPEDIGPDFANLFYRWnigqrVTAINLYMLYGGTNWGAIA-APVVASSYDYSSPISENRTIGAKYYETKLL 388
                     ***************998899999******************.77788*********************9987 PP

>> BetaGal_dom4_5  Beta-galactosidase jelly roll domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.1       3.1   1.1e+04      50      66 ..     441     458 ..     426     499 .. 0.51
   2 !   81.8   0.5   1.4e-26   5.1e-23       1     114 []     692     806 ..     692     806 .. 0.93
   3 !  118.4   0.1   6.3e-38   2.3e-34       1     114 []     859     970 ..     859     970 .. 0.94

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 3.1
  BetaGal_dom4_5  50 gldvslsltl.sggtafr 66 
                     ++d++++l++ ++++af 
      EEA21927.1 441 STDETFQLHVnTSAGAFS 458
                     355555555543333333 PP

  == domain 2  score: 81.8 bits;  conditional E-value: 1.4e-26
  BetaGal_dom4_5   1 Yder.qgwhlpgkttsnnskwplt..vlyssdygfhagvrlyrgtfdldlpsgldvslsltlsggtafrvsvwlNGyqlgsyv...phigpqvtF 89 
                     Y+++ ++w+ +++++++n+++p+t  vly+++ygfh+++r++rg+f     +g+++++ l+++gg af++s wlNG+ lgsy+   +   +++t+
      EEA21927.1 692 YKDTsAAWISADHMKTSNPSPPATfpVLYADEYGFHNSIRIWRGYF-----TGNATGVVLKVQGGYAFGFSGWLNGKLLGSYLgnaSVEHSHLTL 781
                     5565489***************99**********************.....********************************764446778888 PP

  BetaGal_dom4_5  90 pvpegilnyngenvlavlvdamged 114
                     p++  ++ ++++nvl +++d++g+d
      EEA21927.1 782 PFNVSHVSTSSDNVLVIVHDDTGHD 806
                     ***********************97 PP

  == domain 3  score: 118.4 bits;  conditional E-value: 6.3e-38
  BetaGal_dom4_5   1 Yderqgwhlpgkttsnnskwpltvlyssdygfhagvrlyrgtfdldlpsgldvslsltl...sggtafrvsvwlNGyqlgsyvphigpqvtFpvp 92 
                     Y+er+gwhlpg+++   + w+   + s+   ++a++++yr+t++l++p+g+dvs+s++l   ++++afr ++++NGyq+g+++p +g+q++Fpvp
      EEA21927.1 859 YAERMGWHLPGFND---NAWS--DAGSKLNFTGADIKFYRTTVPLNIPKGVDVSISFELsacGTTNAFRSQLFVNGYQMGRFNPWVGNQIEFPVP 948
                     9*************...5699..345555559*************************************************************** PP

  BetaGal_dom4_5  93 egilnyngenvlavlvdamged 114
                     +gil+y+g+n+++++++a++ed
      EEA21927.1 949 PGILDYTGDNTIGLSLWAQTED 970
                     *******************986 PP

>> BetaGal_dom2  Beta-galactosidase, domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  187.0   0.2   7.7e-59   2.7e-55       4     181 .]     401     586 ..     398     586 .. 0.92

  Alignments for each domain:
  == domain 1  score: 187.0 bits;  conditional E-value: 7.7e-59
                   E---BSS.SS.BS-TTEEEEEEE-.STT-EEEEEEESSTT---EEEE-EEEEETT.EEEEE-TTSS-EEEESS-EEEEEEEEEETTEEEEEESSEEE CS
  BetaGal_dom2   4 tervgngtsyttsnsaiavtelrnpdtkasFyvvrhadysslestsfklkvnTsaaGnltiPqlggsltLngrdSKilVtDYdvGgktLlYStAEvl 100
                   t+ +gngt+y ++n+ai + ++rnp t+++Fyv+ h+ +ss+++++f+l+vnTs aG+++iP++g+s++Lng++SKi+VtD+++G ++LlYStAEvl
    EEA21927.1 401 TDLIGNGTQY-STNPAIQTHVIRNPITNGTFYVTLHTISSSSTDETFQLHVNTS-AGAFSIPRYGNSIRLNGHQSKIIVTDFQFGTHKLLYSTAEVL 495
                   7889******.5******************************************.6***************************************** PP

                   EEEEETTEEEEEEEE-TT-EEEEEEE-......SS-..EEEEEST...EEEE....-SSEEEEEEE--SS.-EEEEET.TEEEEEEEHHHHTTE CS
  BetaGal_dom2 101 TwkklddktvlvlYggegetgefalkg......kskgsssvvegs...kiks....kngalvlnwytqsegrtvvklgngllvylldrnsAynf 181
                   T+++ld+ ++l l++++ge+gef++ g       +++ +s ++++   +  +    + + l+++ +tq++g++v+kl+ gl+v+lldr+sAy f
    EEA21927.1 496 TYTVLDGIPTLALWVPTGESGEFSVLGgkwasvLRCEWCSDIQFHpeqD--QtsnpTVSRLTVS-FTQGQGMSVIKLDTGLRVVLLDRESAYYF 586
                   **************************99999887778888888876431..34455666699**.99*************************87 PP

>> BetaGal_dom3  Beta-galactosidase, domain 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.1   0.0   4.9e-28   1.7e-24       1      76 [.     587     661 ..     587     662 .. 0.98

  Alignments for each domain:
  == domain 1  score: 85.1 bits;  conditional E-value: 4.9e-28
  BetaGal_dom3   1 WvpdltssPaesenessviVkGpYLvRsasisgstLaltGDlnatttleviapssvktltwNgkklettktkyGsl 76 
                   W+p+l+s+P+++e++ sv+V+Gp+LvRsa+i gst++ltGD+ +t+++ev+ap++v+ + wN+k+l+t+kt+y sl
    EEA21927.1 587 WAPALNSDPSVPEDQ-SVLVQGPHLVRSAKIVGSTIRLTGDSAQTSPIEVFAPKQVRIIFWNDKELKTSKTSYDSL 661
                   ************888.*********************************************************987 PP

>> Cellulase  Cellulase (glycosyl hydrolase family 5)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.4   0.3   5.6e-10     2e-06      17     146 ..      59     202 ..      37     289 .. 0.80

  Alignments for each domain:
  == domain 1  score: 27.4 bits;  conditional E-value: 5.6e-10
                 TSCGG..SHHHHHHHHHHHT-SEEEEEEECTGGTTSSTTTGCTHHHHHHHHHHHHHHHHTT-EEEEEEESS..........TTT.......CSSSSTTT CS
   Cellulase  17 wgnpy..ttkalidevkdagfntvRlpvswgelvenapdykvdenslerveevvkyakenglyvildiHse..........egw.......ltkadgns 96 
                 w  p    + ++++++k+agf+++ + v w ++ +n+ ++   ++   +++ ++k ak+ glyv+l +  +          ++w         ++d + 
  EEA21927.1  59 WRIPVpeLWIDILEKIKAAGFTAFGIYVNWAYHAPNNYTV-DFATGAHDITPILKMAKDVGLYVLLRPGPYinaevnaggfPLWvttgeygSLRNDDSR 156
                 544445578899**********************988887.44688999*******************9999999999999888776665655666777 PP

                 THHHHHHHHHHHHHHHHHHHT..TTTTTEEEESSSS--STTCTCCTCHHHTT CS
   Cellulase  97 sedtaeeffkklwtqiAeryk..kndevvifelmNEPhgnntgaewtseead 146
                 ++++ e +f+k + +iA++y+  k  +vv + + NE+ ++     wt + + 
  EEA21927.1 157 YTAAWEPYFTK-ISEIASEYQitKGGNVVTYQIENEFGDQ-----WTGSPSR 202
                 77778889***.********8668889************3.....5333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1009 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       407  (0.0227007); expected 358.6 (0.02)
Passed bias filter:                      367  (0.0204696); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.74u 0.30s 00:00:01.04 Elapsed: 00:00:00.48
# Mc/sec: 6362.47
//
Query:       EEA21928.1  [L=378]
Description: oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.1e-17   65.0   0.0    2.6e-17   63.8   0.0    1.6  1  GFO_IDH_MocA   Oxidoreductase family, NAD-binding Rossmann fo
  ------ inclusion threshold ------
      0.015   16.0   0.1      0.027   15.1   0.1    1.4  1  NAD_binding_3  Homoserine dehydrogenase, NAD binding domain


Domain annotation for each model (and alignments):
>> GFO_IDH_MocA  Oxidoreductase family, NAD-binding Rossmann fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.8   0.0   2.9e-21   2.6e-17      12     119 ..      27     137 ..       5     138 .. 0.91

  Alignments for each domain:
  == domain 1  score: 63.8 bits;  conditional E-value: 2.9e-21
                   HHHHHHHHHHTTTTEEEEEEECSSHHHHHHHHHHTTHE....EESSHHHHHTCTTESEEEE-S-GGGHHHHHHHHHHTT-EEEEESSS-SSHHHHHH CS
  GFO_IDH_MocA  12 gskhlrplnesqrleevvalldpdaeraeavaesfgve....aysdleelladpeidavivatpngtheelakaaleagkhvllEKPlattveeake 104
                   g  hl +    ++++++val+++  e+a++  e+ +++    ay + eel++dp+id+v+v ++ ++h++l+k al+++k+v++E Pl+ ++++a+e
    EEA21928.1  27 GLAHL-ACLTGSPHYKLVALCNSTVEKAQKSIEHNKLDpatkAYGSAEELAQDPDIDLVVVSVHVDKHYALVKPALQKKKSVFVEFPLSGSYKQAEE 122
                   66777.666666999****************888888776779999*************************************************** PP

                   HHHHHHHHTS-EEEE CS
  GFO_IDH_MocA 105 lvelaekkgklvsvg 119
                   +++la+++g++  vg
    EEA21928.1 123 MADLARQAGVKTVVG 137
                   *********998876 PP

>> NAD_binding_3  Homoserine dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.1   0.1     3e-06     0.027      21     114 ..      39     134 ..      24     137 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 3e-06
                    EEEEEEEEESS.EEE-TT..HHHHHT--CB---HHHHHHHHS-EEEEE-S--HHHHTTHHHHHHTTEEEE-S--CGGG-HHHHHHHTSSSTTS--. CS
  NAD_binding_3  21 elelvavadrd.sllskd..rkallasealtldlddliahldpdvvVEcasseavaelvlkaLkagkdvvtankgaladealyeeLreaaeangak 113
                     ++lva++++   +++k     +l ++++ + + ++l++++d+d+vV   +++    lv +aL+++k+v +      +  ++ ee++++a+++g+k
     EEA21928.1  39 HYKLVALCNSTvEKAQKSieHNKLDPATKAYGSAEELAQDPDIDLVVVSVHVDKHYALVKPALQKKKSVFVEFPLSGS-YKQAEEMADLARQAGVK 133
                    5799******966655557666677889999**************************************998777777.88888999999998887 PP

                    E CS
  NAD_binding_3 114 i 114
                     
     EEA21928.1 134 T 134
                    6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (378 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       468  (0.026103); expected 358.6 (0.02)
Passed bias filter:                      431  (0.0240393); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.22s 00:00:00.72 Elapsed: 00:00:00.39
# Mc/sec: 2872.37
//
Query:       EEA21929.1  [L=541]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-07   30.9  10.0    2.2e-07   30.9  10.0    1.8  2  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.9  10.0   1.2e-11   2.2e-07       1      34 [.       7      39 ..       7      43 .. 0.92
   2 ?   -4.4   1.5         1   1.8e+04      29      31 ..     250     252 ..     238     259 .. 0.47

  Alignments for each domain:
  == domain 1  score: 30.9 bits;  conditional E-value: 1.2e-11
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfys 34
                ++C +Cr+ K +C++ +P+Cs+C ++++ C  y+
  EEA21929.1  7 KSCVRCRQSKLRCNQATPSCSRCSERGVRCL-YD 39
                59****************************8.54 PP

  == domain 2  score: -4.4 bits;  conditional E-value: 1
                 HHC CS
     Zn_clus  29 eCt 31 
                 +C 
  EEA21929.1 250 DCA 252
                 333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (541 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       395  (0.0220313); expected 358.6 (0.02)
Passed bias filter:                      253  (0.0141112); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.47
# Mc/sec: 3439.25
//
Query:       EEA21930.1  [L=251]
Description: GPI anchored cell wall protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
      0.063   12.5   5.0       0.11   11.8   5.0    1.4  1  DNA_processg_A  DNA recombination-mediator protein A


Domain annotation for each model (and alignments):
>> DNA_processg_A  DNA recombination-mediator protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   5.0   5.9e-06      0.11      76     171 ..      52     148 ..      28     171 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 5.9e-06
  DNA_processg_A  76 vSGlA...lGiDaaahraaleaggktvavlgtgldkiyPkenrklleeiaeegglllseyppgtkpkkenFpeRnriiaglseavlvveaaekSG 167
                     +SG+A   +G D+ a + al+ ++ t +vlgt   +  ++  ++++ +i+ +   +    +  t + + +     +  ++ ++ ++ vea+ +S 
      EEA21930.1  52 ISGVAgsiVGADSTATTIALNCNNGTPCVLGTNP-ITLTQGRSTWVADIVTQ-ASIEGRSATVTAAVACKIISSTQAATCTATVTIGVEAQGQSS 144
                     566554448***********************98.77799*********966.899999999999999999999999999999999999999999 PP

  DNA_processg_A 168 alit 171
                     al+ 
      EEA21930.1 145 ALTI 148
                     9853 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (251 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       967  (0.053935); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 1737.85
//
Query:       EEA21931.1  [L=541]
Description: MFS sugar transporter protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-62  211.3  32.1    2.6e-62  211.2  32.1    1.0  1  Sugar_tr  Sugar (and other) transporter
    4.1e-25   88.4  35.8    5.6e-25   88.0  35.8    1.2  1  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  211.2  32.1   2.9e-66   2.6e-62       3     452 .]      61     511 ..      59     511 .. 0.89

  Alignments for each domain:
  == domain 1  score: 211.2 bits;  conditional E-value: 2.9e-66
                 HHHHHHH.HHHHH..HHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTT CS
    Sugar_tr   3 lvaalgg.llfgY..dtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakg 98 
                 l++ + g  + gY  d gvig++ ++++ ++ fg+ +s +        +g i+++++vG i+G+ f++ l+d++GR+ +  i++++++++a++q++a+ 
  EEA21931.1  61 LIMFVQGcNQAGYgiDWGVIGGINAFPALHSYFGFGTSGGV-------VGTITALMSVGNIAGAPFLS-LADVIGRRGINFIGNMIVIVAAIMQGCAP- 150
                 55555554455554499**********************84.......478*****************.9****************************. PP

                 TSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHG.GGS---HH CS
    Sugar_tr  99 knsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllill.lflPESPr 196
                   ++ vl++gR+l+G+g   a + ++ y++EiAp +lRg+lv+++  + ++G lv  +++lgl+k+s+++ wri++ l+++++l++++ + ++ PE+Pr
  EEA21931.1 151 --NLSVLMAGRFLLGFG--SAMMSSSQYMGEIAPVHLRGRLVGIFGACFQVGSLVMGGVMLGLSKISGNWSWRIPFLLEALFPLIVCLTIfVLTPETPR 245
                 ..9***********995..677779******************************************99*****************99884677***** PP

                 HHHHTT-HHHHHHHHHHHHHC.HHHHHHHHHHH.HHHHHHHH.........HT.THHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-TH CS
    Sugar_tr 197 ylvekgkeeeakevlaklrge.edadrelaeek.dsleaeqeee....kaswk.ellssktvrqrlligvvlqifqqltGinaimyysptifenlglsk 288
                 y++++g++e+ak+++ak  ++  d+++ +++++ +++e++ e++     ++w+ +++ +k vr+rll+ +++ +fqq +G  +i yy    +e++g++ 
  EEA21931.1 246 YYMMRGQREKAKQIIAKYHTTsGDVNEPIVNIViNQMEESLENKragfRNFWDyRVFFTKAVRYRLLVLILYSVFQQWNGGSIISYYMVPALETIGIDG 344
                 *****************66664455555555441444444444455567777634566666************************************** PP

                 H...HHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS....CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTT CS
    Sugar_tr 289 s...llvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgivalllvaks.kaasivaivfialfialfalgwgpvpwvlvsElfpqsv 383
                 +   l +++++ ++ fv+t  + flvd++ RRtl + G++  +i+ +  +i    ++ +s  aa+++ i+ i++f  + al ++++  ++  E+ ++++
  EEA21931.1 345 TlqqLGISLGTTATYFVFTALGSFLVDKIRRRTLIFSGLISIIIFQTAATITSWQYSLTSsHAAAGLTIFWIFMFQTFSALLIATMHNLYPVEILSLAL 443
                 *98888999999********************99999999999999999843333333334799*********************************** PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 384 Rskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 R+k++ +   ++  a  + ++ + +  +++g +++ +v+ + +++ +   ++ +pet g++leei+++f
  EEA21931.1 444 RAKGMGLYGLIQGGAGAIQTYGIGVGINKLG-YKIWVVYIAYNCVQLGLSYLIFPETFGLSLEEIDAVF 511
                 *******************************.**********************************997 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.0  35.8   6.2e-29   5.6e-25       9     351 ..      74     461 ..      59     463 .. 0.72

  Alignments for each domain:
  == domain 1  score: 88.0 bits;  conditional E-value: 6.2e-29
       MFS_1   9 alarsilgpalpl.alaed..lgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll.fasslwlllvlrvlqGlgagalf 103
                 +++++++g +    al +   +g s+ ++g++++l ++g ++++++l+  +d +Grr + ++g  + +++ +++   a++l +l+++r+l G+g+  ++
  EEA21931.1  74 GIDWGVIGGINAFpALHSYfgFGTSGGVVGTITALMSVGNIAGAPFLSL-ADVIGRRGINFIGNMIVIVA-AIMQgCAPNLSVLMAGRFLLGFGS--AM 168
                 44455555554433444443366***********************975.5*******999999999999.55554348888************5..44 PP

       MFS_1 104 pagaaliadwfpkeergraigllsagfslGailgpllggllasslg...Wravfyilaivsllafvlfllllpeepperkrkspkeee..........k 189
                  ++  ++ +++p   rgr +g+++a+f++G+++  ++   l+   g   Wr +f++ a++ l++++ +++l pe+p+      ++e+           +
  EEA21931.1 169 MSSSQYMGEIAPVHLRGRLVGIFGACFQVGSLVMGGVMLGLSKISGnwsWRIPFLLEALFPLIVCLTIFVLTPETPRYYMMRGQREKAkqiiakyhttS 267
                 5555688************************999888888876666677***************99555555555555555555555588899999996 PP

       MFS_1 190 gtgpaplvp...............awkallkdpvlw.......illialllfffgfsg...lltllplylqevlgls.glllaglllallalvgailal 262
                 g+++ p+v+               +++ ++  +v++       +l+++l+++f  ++g   +++++   + e+ g++ +l ++g+ l+ +a  +++   
  EEA21931.1 268 GDVNEPIVNivinqmeeslenkraGFRNFWDYRVFFtkavryrLLVLILYSVFQQWNGgsiISYYMVP-ALETIGIDgTLQQLGISLGTTATYFVF-TA 364
                 77777777777777777777778877777777777334444475666666666666666666666666.49******8778888555555555544.46 PP

       MFS_1 263 lagrlsdrlgrrrrlllallllllaalglallavt...ssavllllvlvliGfglgfvfpsllalasdlapp.....eeagtasglfntagslggal 351
                 l+++l+d++ rr+ ++ +l++++++  +  ++++    +s+++++ + +++ f + +++++l+a + +l+p        +++ +gl++++++ +ga+
  EEA21931.1 365 LGSFLVDKIRRRTLIFSGLISIIIFQTAATITSWQyslTSSHAAAGLTIFWIFMFQTFSALLIATMHNLYPVeilslALRAKGMGLYGLIQGGAGAI 461
                 888888**9999999999999999999999999996554444444344444444444444444444445544777779999*******999988887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (541 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       594  (0.0331307); expected 358.6 (0.02)
Passed bias filter:                      302  (0.0168442); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 3704.89
//
Query:       EEA21932.1  [L=755]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.2e-62  210.5   0.0    4.2e-62  210.1   0.0    1.2  1  Glyco_hyd_65N_2  Glycosyl hydrolase family 65, N-terminal dom


Domain annotation for each model (and alignments):
>> Glyco_hyd_65N_2  Glycosyl hydrolase family 65, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  210.1   0.0   2.3e-66   4.2e-62       1     236 [.       5     247 ..       5     248 .. 0.96

  Alignments for each domain:
  == domain 1  score: 210.1 bits;  conditional E-value: 2.3e-66
  Glyco_hyd_65N_2   1 LwykqPAtnweeaLplGNGrlGamvfGgvakEriqlNedtlWsGgprsnnnynaaeaLeeiRallfagkykeaeelaketlggesss.gayqpl 93 
                      Lwy+qPA+ w+eaLp+GNGrlG+mv+G++++E + lNed++W Ggp+s++++++ ++L+ +R+l+ ++k++ ae+la++ ++  ++s ++y+pl
       EEA21932.1   5 LWYQQPAQCWNEALPVGNGRLGVMVYGRTSTELLALNEDSVWYGGPQSRTPQPSIGELALLRDLIRKEKHTDAEKLARKSFFASPASqRHYEPL 98 
                      8*************************************************************************************8799**** PP

  Glyco_hyd_65N_2  94 gdLtld.qsgdsskvtnYrReLDlstaiatveYsvegvtytrevfaSapdqVlvvrlsaskagklnltvslesele.......kktketvkgnt 179
                      g++++d ++++++k  +Y+R+LD+++++++veY+++g  + r+ +aS+pd+Vl++++++s++  +++tv+l++ +e         + +++kgn+
       EEA21932.1  99 GTVFIDfNHDNEQKLLDYQRSLDIEKSLCHVEYEYDGICIARDLIASYPDSVLAMHIQSSAP--IEFTVRLTRVNEldyetneFLDDVAAKGNS 190
                      ******8889999999**********************************************..**********9999998888899999**** PP

  Glyco_hyd_65N_2 180 ltlrgalkaekdnglkfeailrvvatgGsv.aadggtltvegadevtlviaaaTdykk 236
                      l+++ +   + +n+  +   +r+++++G v a  +++l+++g ++++lviaa+T+y++
       EEA21932.1 191 LVMSVTPGGKRSNRACCVLSARCIDDEGIVtARPNNSLHIRG-QNILLVIAAQTEYRC 247
                      ***99998789999999999999*******88899*****96.578999*******86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (755 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       346  (0.0192983); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.27s 00:00:00.88 Elapsed: 00:00:00.45
# Mc/sec: 5056.35
//
Query:       EEA21933.1  [L=491]
Description: beta-glucosidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   2.2e-143  478.0   2.7   2.7e-143  477.7   2.7    1.0  1  Glyco_hydro_1  Glycosyl hydrolase family 1


Domain annotation for each model (and alignments):
>> Glyco_hydro_1  Glycosyl hydrolase family 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  477.7   2.7  1.5e-147  2.7e-143       3     449 ..      11     486 ..       9     488 .. 0.93

  Alignments for each domain:
  == domain 1  score: 477.7 bits;  conditional E-value: 1.5e-147
                    GGS-TT-EEEEE--HHHHH--TTSTT---BHHHHHHHHGGGSTTS---SSTT-HHHHHHHHHHHHHHTT-SEEEEE--HHHHSTTS..TT---HHH CS
  Glyco_hydro_1   3 etfpedFlwgaataayqiEGawnedGkgesiwDtftetpgkvlegsngdvacdsYhrykeDvallkelgvkayrfSisWpRilPkG..egeinekG 96 
                     ++++dF +g ataa q+EGaw+ dGkg++iwDtf++t  +v+++s+ d a+ sY+ yk+Dv+l+k  gv+ayrfS+sW+Ri+P G  +  +nekG
     EEA21933.1  11 GSLRHDFFHGYATAATQVEGAWDRDGKGPTIWDTFAHTSDQVIDKSTPDEAVRSYDLYKQDVNLMKSYGVNAYRFSLSWARIIPLGgkDDPVNEKG 106
                    57899********************************************************************************998889***** PP

                    HHHHHHHHHHHHHTT-EEEEEEESS--BHHHHH.H-GGG-.SHHHHHHHHHHHHHHHHHTTT--EEEEEE-HHHHHHHHHTSS-STT-........ CS
  Glyco_hydro_1  97 layYerLidelleagieplvTlyHwdlPqaLqd.eGgwen.rsiidafkeyaevvfkrfgdkvklwlTfnEpnvvallgyltgefaPg........ 182
                    ++yY++Lidell ++i+p+vTl+Hwd+PqaL+d +Gg  n  + i +f +ya+++f+rfgd+vk+w+T+nEp v+al+gy  g++aP         
     EEA21933.1 107 IEYYSNLIDELLRNNITPFVTLFHWDVPQALEDrYGGMLNqGAYIPDFVRYATMCFERFGDRVKHWITYNEPGVFALAGYAAGVHAPArssfrdrn 202
                    *************************************9993578*************************************************999 PP

                    ..S-TTTHHHHHHHHHHHHHHHHHHHHHHHT...TT-EEEEEEEEEEEEESSSSHH.HHHHHHHHHHHHTHHHHHHHHH.SS--HHHHHHHGGG.. CS
  Glyco_hydro_1 183 ..kkdleaayeaaHnlllaharavklykeva...qkgkigivlnlslaeplsesee.dkeaaeraleflngwfldpvvk.GdYpeemkellrerga 271
                       ++ ++++ ++H++l++h+++ kly+e+    qkg +gi+l+ ++ ep + s + d+eaaera+ef   w++dpv k GdYp++m+ +l++r  
     EEA21933.1 203 dvGDSSTEPFIVGHTQLVSHGHVAKLYREKFrptQKGVLGITLHGNWSEPWDLSDPlDQEAAERAREFEIAWYADPVHKsGDYPASMRAQLGDR-- 296
                    9889999***********************9999*****************98766166***********************************.. PP

                    S----HHHHHHHTT--SEEEEEEEEEEEEEE--....-STT---SSGGGGG-..SBSS-B-SSSS-B-.HHHHHHHHHHHHHTS----EEEEE--- CS
  Glyco_hydro_1 272 lpeiteedkellkgkadflglnyYtsrlvknkes.eeaslskteekkleeev..dpslpktdigwiie.peglrkllellkkeYqklpiyiteNGl 363
                    lp +tee+ +l+ ++ df g+n Yts +v++k++ ++++ +k + ++++e++      p +d++w  + p+g+rkll+++  +Y  +piy+teNG 
     EEA21933.1 297 LPRFTEEESKLVLDSSDFYGMNSYTSFFVRHKTTpPDINDHKGNIDQFDENKegVSRGPASDTYWLRTsPWGFRKLLNWIWARYY-KPIYVTENGT 391
                    ******************************99851455666666666666552246789*******999***************9.9********* PP

                    -EE-BSSS.......HHH--HHHHHHHHHHHHHHHHHH.HTT--EEEEEEE-SB----GGGTTSEE--SEEEET.TTTTEEEE-HHHHHHHHHHH CS
  Glyco_hydro_1 364 gakdeiee.......gkveDdkRidYlkehlnevkkai.edgvdlkgYvawsllDnfewaegyskrfGlvyvdr.netleRtpkkSakwykevie 449
                    +ak e          + ++D+ Rid++k ++ e+++a+ edgvd+++Y+aw+++Dn ewa+gy++rfG+++vd+ + +++R+pk+Sa++++++ e
     EEA21933.1 392 TAKGENDInpathesQIIDDQFRIDFFKGYVGELARAVkEDGVDVRSYFAWTFTDNWEWAAGYTDRFGVTFVDFdTPDKTRYPKQSAYYLRSLFE 486
                    99876432466667678999******************99**********************************999*************99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (491 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       355  (0.0198003); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.54
# Mc/sec: 2713.24
//
Query:       EEA21934.1  [L=544]
Description: amino acid permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.6e-55  187.2  45.1    6.6e-55  186.6  45.1    1.1  1  AA_permease_2  Amino acid permease
    1.9e-32  112.5  31.8    1.9e-32  112.5  31.8    2.1  2  AA_permease    Amino acid permease
  ------ inclusion threshold ------
       0.16   12.1   0.2       0.24   11.5   0.2    1.2  1  MYO10_CC       Unconventional myosin-X coiled coil domain


Domain annotation for each model (and alignments):
>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  186.6  45.1   1.1e-58   6.6e-55      23     423 ..      61     519 ..      42     524 .. 0.83

  Alignments for each domain:
  == domain 1  score: 186.6 bits;  conditional E-value: 1.1e-58
  AA_permease_2  23 n.........laasggpalilwvwiavligslavllvyaEl.ssalprsgGiyvytkaaf....gkkvaflsawfnwfayvpvlasilsv...aas 101
                               + +ggpa +++++++v +g++a +++  E+ s   p+ gG+y++ + +     +k+  ++++w++++++ +++a+++++   +++
     EEA21934.1  61 WeaelttflqPLQNGGPAGAVYGFLIVWAGLIATFITVSEMvSM-APTTGGQYHWCSMLAgrsvSKFSSYVTGWLTVVGWQATFATGCYLngtLVQ 155
                    23444555557899****************99999999***555.9*************8444456666******************987444677 PP

  AA_permease_2 102 yllnalgpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfsslstetdtffpn.gwpg....vll 192
                     l+ ++ p+++++ w+  l+++ai+++ ++in++g + + k+   + +l+il++  ++ii++li+ +++ +       +t++++  wp+    +l+
     EEA21934.1 156 GLIILTRPEYEPHAWHGTLFYWAIVVFSVAINVIGGSLLPKFEGLILVLHILGF--FAIIIPLIYMSNHDNAI--EVFGTWVNSgDWPSqgisTLV 247
                    77787899*******************************************866..78888****97776653..4455666665888545546** PP

  AA_permease_2 193 gllivlwsfdGfesaanvseevkk..kdvpkaifigllivlvlyllvniaflgvvpd..deianlsnlgsvaalffeavggkvvaiivvilialsl 284
                    gl++++++f+G ++a++++ee k+  k +p+ i+++l+i +v+++ + ia l++++   d i++  +   ++++f++ +++ ++a +++ ++++ +
     EEA21934.1 248 GLMGAVFAFAGGDAAVHMAEETKNaqKVIPISIMLSLMINGVMGFAMLIATLFCIGNiqDAIESKTG-YPFMEIFYQGTNSIAGACVMATIMVIMS 342
                    *********************9998789*************************99985455665555.3379********7799999999999999 PP

  AA_permease_2 285 lgaintavigssrvlealardgvlP..rffakvn.kfgspiraiiltaivslillllfllassaaynfllsvsslgliisyllliigalilrkkrp 377
                    + a+++ ++++sr+++a++rd++ P    ++k++ ++++p++++ilta+vs++l+l+ ++ s  a+n l+s+s+ gl++sy+++ i++l+ r +  
     EEA21934.1 343 ICAVTGILATTSRQFWAFSRDRGVPgwQIWSKISeRTNIPVNSVILTAVVSCLLGLIPIG-SPIAFNDLTSMSTSGLYLSYMICCILLLYRRCTGG 437
                    99**************************************************99866655.5699*****************************99 PP

  AA_permease_2 378 hl....kr..................pgk...............ilvaiigalfllfllvalffppkgpatqssliytiiltv 423
                    +l     r                                    i+v+ i++++ ++++++ f+pp   +t  +++y+ +++ 
     EEA21934.1 438 ILemddYRsrnsagiqsevdeniintA-GaklvwgpfhlkgipgIVVNVIAIIYMIIAVFFSFWPPTAEVTAATMNYSAVGIT 519
                    885544225576666655555555550.055566667888888899********************************77664 PP

>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.5  31.8   3.2e-36   1.9e-32      23     388 ..      72     430 ..      65     436 .. 0.86
   2 ?   -1.4   4.9      0.11   6.4e+02     405     460 ..     472     527 ..     461     537 .. 0.57

  Alignments for each domain:
  == domain 1  score: 112.5 bits;  conditional E-value: 3.2e-36
  AA_permease  23 lsqaGplgallayllagvviflvmlslgeiatngpksggfytyas....rflgpelGfviGlnylfswitvlaleltaasiliqfwel..vtdlpkaw 114
                  l+++Gp+ga+ ++l++++ ++++ ++++e++++ p +gg y++ s    r++++  ++v+G+++++ w +++a ++   + l+q +     +++   +
   EEA21934.1  72 LQNGGPAGAVYGFLIVWAGLIATFITVSEMVSMAPTTGGQYHWCSmlagRSVSKFSSYVTGWLTVVGWQATFATGCYLNGTLVQGLIIltRPEYE-PH 168
                  899*************************************987662222777777789********************99999977652244444.67 PP

  AA_permease 115 vt.....gavflvvlliinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkgagfrflgdngsifknnlppgfakeeegafknfisvfvi 207
                  ++        ++v+ ++in++g  +  ++e +++++ i+ + a ii +i ++  ++ + +  f  + ++g+    + ++g          + +++++ 
   EEA21934.1 169 AWhgtlfYWAIVVFSVAINVIGGSLLPKFEGLILVLHILGFFAIIIPLIYMSNHDN-AIE-VFGTWVNSGD----WPSQG---------ISTLVGLMG 251
                  77955553334455567999999999999999999999999998888865555555.555.5888888888....77777.........67899**** PP

  AA_permease 208 vvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasaaspfvifikesgvsvlaplinaviltaalssan 305
                  +vfaf+G  + + +a+E+k+ +k iP++i+  +++ +++   +l++  ++++   + + +++  +++ ++if + +++++ a +++ +  +  + ++ 
   EEA21934.1 252 AVFAFAGGDAAVHMAEETKNAQKVIPISIMLSLMINGVMGFAMLIATLFCIGNIQDAIESKT--GYPFMEIFYQGTNSIAGACVMATIMVIMSICAVT 347
                  ****************************************9999998888887776666644..578******************************* PP

  AA_permease 306 sslysasRvlyslakdglaP...kvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliilsyl 388
                  ++l+++sR+++++++d+  P    + k +++ + P+++++l++++s+l+ l+   +++   +fn l ++s+    + ++++++ +l
   EEA21934.1 348 GILATTSRQFWAFSRDRGVPgwqIWSKISERTNIPVNSVILTAVVSCLLGLIPIGSPI---AFNDLTSMSTSGLYLSYMICCILLL 430
                  **********************9999999**********************9988888...*********************9887 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.11
  AA_permease 405 gfkaallplgvilvlaaliii.llilalyayltvkkgpkdwgaasfaaaylivllfl 460
                  +f++ ++p +v++v+a++ +i +++ +++++++   + ++++++ +  + +++l ++
   EEA21934.1 472 PFHLKGIPGIVVNVIAIIYMIiAVFFSFWPPTA-EVTAATMNYSAVGITGVMLLTVV 527
                  677778888888888877544044444555544.44444444444444444433333 PP

>> MYO10_CC  Unconventional myosin-X coiled coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.2   4.1e-05      0.24      17      51 ..       2      37 ..       1      38 [. 0.90

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 4.1e-05
    MYO10_CC 17 erLqrqkedqvsslceesrqelqrlRde.elkrLek 51
                e+Lq +k+++ s+++e+   +  r+Rde +l rL k
  EEA21934.1  2 EALQMKKQNHNSVSTENGTPRTPRQRDEaQLARLGK 37
                89************************8648999976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (544 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       767  (0.0427799); expected 358.6 (0.02)
Passed bias filter:                      277  (0.0154498); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.32s 00:00:00.92 Elapsed: 00:00:00.46
# Mc/sec: 3521.86
//
Query:       EEA21935.1  [L=369]
Description: hypothetical protein PMAA_057240 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.015   15.5   3.3      0.015   15.5   3.3    2.6  3  DUF4418   Domain of unknown function (DUF4418)
        1.7    7.9  10.4        1.4    8.2   3.8    2.1  2  DUF3810   Protein of unknown function (DUF3810)


Domain annotation for each model (and alignments):
>> DUF4418  Domain of unknown function (DUF4418)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.3      0.48   4.3e+03     101     111 ..      21      31 ..      14      44 .. 0.53
   2 ?    0.1   0.7       0.1   8.9e+02      29      58 ..      88     117 ..      49     146 .. 0.65
   3 ?   15.5   3.3   1.7e-06     0.015      35     102 ..     174     265 ..     171     276 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.48
     DUF4418 101 livlgillill 111
                 l+v+ i+ +l+
  EEA21935.1  21 LLVVVIIAVLI 31 
                 33333333322 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.1
     DUF4418  29 MkChytgqaelgvGivllvlgllalfvkkk 58 
                  kC y+++  +++ + l  ++ ++++   +
  EEA21935.1  88 QKCTYAQHELIIMTMTLSKTSFIMFVKSIT 117
                 789998888888888777777776654444 PP

  == domain 3  score: 15.5 bits;  conditional E-value: 1.7e-06
     DUF4418  35 gqaelgvGivllvlgllalfvkkkklrrglsiavillgvlviliptvl........................igvCkkpemeChatakpvli 102
                 g +++ vGiv+  + ++  + +k ++r+gl+i++ +  +++++i+ ++                        i +C+++ ++C+  +kp+l 
  EEA21935.1 174 GDIVTDVGIVIYTMIIIVRIRTKLSMRMGLAIVFGMRVLVIVAIVVHIttlnmsfaandstykswvatiasqIAICMSNVTACSPQFKPFLE 265
                 677899***********99999999********9999999999997777889*********************************9999885 PP

>> DUF3810  Protein of unknown function (DUF3810)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.5     0.004        36      22      89 ..      11      81 ..       3     107 .. 0.65
   2 ?    8.2   3.8   0.00015       1.4      22      81 ..     171     229 ..     167     246 .. 0.83

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.004
     DUF3810 22 FSvgellivllillvilylvlai...klkkrkkkkkrllkvllrvllvllvvyflftllwglnYyreplse 89
                  v++++  +l+++vi+++++ +   ++  rk +k   + +l +++ +  v+++    + g+  + ++lse
  EEA21935.1 11 TPVVDVMTWFLLVVVIIAVLIRLgtkIWIFRKLHKDDYIMILSAIFDIGQVICVSIAGMNGYGRHIKTLSE 81
                56777777666666666666666666344455566677778888888888888877777777766666665 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.00015
     DUF3810  22 FSvgellivllillvilylvlaiklkkrkkkkkrllkvllrvllvllvvyflftllwgln 81 
                 FS+g+++  + i++ ++++++ i ++k   +   ++ + +rvl+++++v+ + tl++ + 
  EEA21935.1 171 FSIGDIVTDVGIVIYTMIIIVRI-RTKLSMRMGLAIVFGMRVLVIVAIVVHITTLNMSFA 229
                 9*******999888888888888.3445555577888999999*****999999998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (369 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       998  (0.055664); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.24s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2662.40
//
Query:       EEA21936.1  [L=254]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      0.002   18.1   0.0     0.0036   17.2   0.0    1.3  1  Acetyltransf_10  Acetyltransferase (GNAT) domain
     0.0045   17.2   0.0     0.0068   16.6   0.0    1.4  1  Acetyltransf_1   Acetyltransferase (GNAT) family
  ------ inclusion threshold ------
      0.026   15.0   0.0      0.042   14.3   0.0    1.3  1  Acetyltransf_7   Acetyltransferase (GNAT) domain


Domain annotation for each model (and alignments):
>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   6.1e-07    0.0036      58     110 ..     150     200 ..     136     204 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 6.1e-07
  Acetyltransf_10  58 fVdpeyrgqGigkaLleaveeeaekdgikleltvnaspyavpfYeklGFkavg 110
                      f   e+r++G+++  l+  +++a++ g++  + ++as + +p+YeklGF ++g
       EEA21936.1 150 FTVLEHRRKGVANLFLNWGLNRADELGLG--TWLDASEHGKPVYEKLGFIPHG 200
                      77789******************888766..99****************9876 PP

>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   1.1e-06    0.0068      44     117 .]      83     196 ..      31     196 .. 0.68

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 1.1e-06
                     EEEEE...............................................EEEEEETTSTTEEEEEEEEESGGGTTSSHHHHHHHHHHHHHHH CS
  Acetyltransf_1  44 liGfi...............................................sllkipdekggvayieslaVspeyrgkGlGsaLlealeerare 91 
                     ++G +                                               ++++     g++a+++  +   e+r+kG++ + l+  + ra e
      EEA21936.1  83 VVGGAkwfffqrnpfvpkpgsdhdpateeavwypegpartfataamhaldrpRMTM---GQGPHAFLNIAFTVLEHRRKGVANLFLNWGLNRADE 174
                     55555555555555555555555555555555555555555555443333333333...3347788888888889******************** PP

                     TTESEEEEEEETTEHHHHHHHHHTTE CS
  Acetyltransf_1  92 egikkivlaveedndaairlYeklGF 117
                      g+   +l+ +   ++  ++YeklGF
      EEA21936.1 175 LGLGT-WLDAS---EHGKPVYEKLGF 196
                     ***99.9*555...555********9 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0     7e-06     0.042      35      75 ..     154     197 ..     126     198 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 7e-06
                     GGTTSSHHHHHHHH...TT..SEEEEE.EEEETHH.HHHHHHHHTTEE CS
  Acetyltransf_7  35 eyrgkGiGraLlea...ae..kgiile.qlelnae.kaikfYeklGFe 75 
                     e+r+kG++   l+    ++          ++l+a+ +  + YeklGF+
      EEA21936.1 154 EHRRKGVANLFLNWglnRAdeL----GlGTWLDASeHGKPVYEKLGFI 197
                     8************844411233....33467844336677*******7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (254 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       314  (0.0175135); expected 358.6 (0.02)
Passed bias filter:                      298  (0.0166211); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 1813.70
//
Query:       EEA21937.1  [L=103]
Description: hypothetical protein PMAA_057260 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (103 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       446  (0.0248759); expected 358.6 (0.02)
Passed bias filter:                      273  (0.0152267); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.37u 0.25s 00:00:00.62 Elapsed: 00:00:00.41
# Mc/sec: 753.30
//
Query:       EEA21938.1  [L=307]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.2e-67  226.3   1.3    4.9e-67  226.1   1.3    1.0  1  SGL           SMP-30/Gluconolactonase/LRE-like region
     0.0036   17.5   0.0     0.0091   16.2   0.0    1.7  1  Arylesterase  Arylesterase
  ------ inclusion threshold ------
      0.036   14.3   1.8          4    8.0   0.1    3.4  2  Reg_prop      Two component regulator propeller


Domain annotation for each model (and alignments):
>> SGL  SMP-30/Gluconolactonase/LRE-like region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  226.1   1.3   8.1e-71   4.9e-67       1     244 [.      17     268 ..      17     270 .. 0.93

  Alignments for each domain:
  == domain 1  score: 226.1 bits;  conditional E-value: 8.1e-71
         SGL   1 lgEGpvwdeeegaLlwvDilgqrihrldpatgketvldtpe..svGaiaprkd..grlvvasksglalldlasgeletladeee......dekpllrfN 89 
                 l+EGp + e++++L ++Di ++ ++ +d+++g+++  +++   s G++a+ ++  + ++++ k+g+ + + +s++++++ + ++      +  + +r N
  EEA21938.1  17 LSEGPFYEEATNTLRFIDIVKKHVWWVDLNKGASSAKKIEYdiSFGVTANLASstDSFLFGGKHGIGIAKRDSSKYKYINRFWNeteianNYETIMRAN 115
                 79********************************986666555777777744467**************99999999998885555677655699**** PP

         SGL  90 DgvvdpdGrlwfGtmgdeeakgeev...galyrldpdgklervlddltipNGlawspdgktlYlaDsltrkiwaydvdaeggklsnrrvfadlkkgege 185
                 Dg++d++Gr+w+G m+d   ++ ++   g l+rld+dg+l+rvl+++tipNG+ +s d+kt+Y++D++t+ i+a+d+d ++g++sn+rvf + + g+  
  EEA21938.1 116 DGAIDSQGRFWVGAMNDPAYTNGKFdpvGILFRLDTDGTLHRVLENVTIPNGISFSLDNKTMYWTDTPTGNIYAFDYDVSTGNISNQRVFWHSDLGG-- 212
                 ***********************99*****************************************************************9888887.. PP

         SGL 186 pDGlavDaeGnvwvAvwgggkvvrfdpdGklieeiklpakrvtscaFgGpdlrtLyits 244
                 pDG a+D eGn+wvA+wgg+kvvr++p+Gk+++ei++p++++t+++F G+d   +yits
  EEA21938.1 213 PDGHAMDVEGNLWVALWGGWKVVRVSPEGKVTAEIEVPTRCPTAVVFVGED---VYITS 268
                 **************************************99**********9...9*998 PP

>> Arylesterase  Arylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   1.5e-06    0.0091      46      82 ..     155     191 ..     151     195 .. 0.90

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.5e-06
  Arylesterase  46 vkvvasglssanGInidadkkyiyvadilresihvmk 82 
                   ++ v + ++ +nGI ++ d+k +y +d    +i++++
    EEA21938.1 155 LHRVLENVTIPNGISFSLDNKTMYWTDTPTGNIYAFD 191
                   5678999***************************976 PP

>> Reg_prop  Two component regulator propeller
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   0.1   0.00067         4      12      22 ..     119     129 ..     103     131 .. 0.84
   2 ?    3.9   0.2     0.014        86      13      22 ..     219     228 ..     217     230 .. 0.78

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00067
                 E-TTSCEEEEE CS
    Reg_prop  12 eDsdGrlWvGt 22 
                  Ds+Gr WvG 
  EEA21938.1 119 IDSQGRFWVGA 129
                 5********96 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.014
                 -TTSCEEEEE CS
    Reg_prop  13 DsdGrlWvGt 22 
                 D +G+lWv+ 
  EEA21938.1 219 DVEGNLWVAL 228
                 779*****85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (307 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       379  (0.0211389); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.24s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 2097.54
//
Query:       EEA21939.1  [L=379]
Description: beta-lactamase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.6e-74  249.1   0.1    7.5e-74  248.9   0.1    1.0  1  Beta-lactamase  Beta-lactamase


Domain annotation for each model (and alignments):
>> Beta-lactamase  Beta-lactamase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  248.9   0.1   4.2e-78   7.5e-74       3     318 ..      17     361 ..      15     373 .. 0.91

  Alignments for each domain:
  == domain 1  score: 248.9 bits;  conditional E-value: 4.2e-78
                     HHHHHHHHHTTESEEEEEEEETTEEEEEEEEEEEETTTTEEESTTSBEEEGGGHHHHHHHHHHHHHHTTSSCTTSBGGGTSTTCTTGGGTTEBHH CS
  Beta-lactamase   3 rlvrelmaqggipGvavavvrdgkvvldkggGvadleggrpvtadtlfriaSvtKtftaaavlqlveeGkldLddpVskylPefagpgkgkiTlr 97 
                     +++++  ++g   G+a++v  dgk+v+d +gG+ad +++rp+t+dt+  ++S+tK +ta+a+l lv++G+ldLd+pV+ky+Pefa++gk+k+ +r
      EEA21939.1  17 EILQKNLDDGEETGAAIYVNLDGKPVVDIWGGYADEKRTRPWTEDTIVNVWSTTKNVTALAALILVDRGLLDLDAPVAKYWPEFAANGKEKVLVR 111
                     567777888889*********************************************************************************** PP

                     HHHTTHSSCSSSSTSTTCTSHHHTHHHHHHHHHHSBSSSSTTSCEE-SHHHHH.HHHHHHHHHHTSHHHHHHHHHTTTTTTSTTEESSTTGGGGG CS
  Beta-lactamase  98 dLltHtsGlpdlfasdlleeaaadaaellralatlppkyapGtkwgYsntgyg.llgellekvtgrsleqllreeilrpLgmkdtelgppesgdp 191
                     ++ +HtsG+++++++ ++ +  +d ++ +++la+++p+++pGt+ gY++++yg l+ge++++v+g+sl++++++ei+rp    d++lg pes+ +
      EEA21939.1 112 HVVSHTSGVSGWDQPFTYSD-IYDLEKSTARLAAQAPWWEPGTASGYHAINYGhLVGEIVRRVSGKSLRDFVKDEIARP-RDADFSLGAPESEWH 204
                     ************55555555.56999*****************************************************.*************** PP

                     GBEEEEEEETCEEECSCETTHHHHC................................TTTBEEEEHHHHHHHH..HHHHHCCSSSSHHHHHHHHH CS
  Beta-lactamase 192 rdaagytgngpearappanlpaeae................................gagglistardlarfl..glalegglllsaetlaqlta 252
                     r+a    +++p  +a+        +                                ga +++++ar l++ +    + ++++lls++t  +  +
      EEA21939.1 205 RLAEII-PPPPADPAAF-------AqldpqsipvktlgigmasasypntavfrkaeiGAINGVTNARALNKIFapLALGGEESLLSPKTIDRIFE 291
                     ******.3333333333.......134444558****************************************99888899************** PP

                     HHTSEEEECTTEEEECECSSEEEEECCH.....TEEEEEEESTEEEEEEEECGGTEEEEEEESBCSSHHHH CS
  Beta-lactamase 253 klssgttrpagiraglglGwvladktga.....pgtfghtGggygtyvfvdpeanlvvavltnrdppneda 318
                      +  g++     + ++g G+ l ++        ++ f++ G ++g++v+vd e++l++++++n++++   +
      EEA21939.1 292 VQADGPDLAVFAPLRWGIGFGLPNPATTpfipeGRVFFWFG-WGGSFVIVDTERKLTITYVMNKMGEGVIG 361
                     ********************999888889************.***********************986555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (379 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       347  (0.0193541); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 2679.67
//
Query:       EEA21940.1  [L=555]
Description: pogo transposable element, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.1e-33  116.3   0.0    2.2e-33  115.3   0.0    1.5  1  DDE_1        DDE superfamily endonuclease
    3.5e-10   39.8   0.5    1.7e-09   37.6   0.0    2.3  2  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
      2e-06   27.4   0.0    5.3e-06   26.1   0.0    1.7  1  HTH_psq      helix-turn-helix, Psq domain
  ------ inclusion threshold ------
       0.08   12.8   1.5       0.14   12.0   1.5    1.4  1  zf-CCHC_2    Zinc knuckle
       0.34   11.0   2.1       0.62   10.3   2.1    1.4  1  zf-CCHC      Zinc knuckle


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.3   0.0   6.2e-37   2.2e-33       2     175 .]     204     373 ..     203     373 .. 0.96

  Alignments for each domain:
  == domain 1  score: 115.3 bits;  conditional E-value: 6.2e-37
       DDE_1   2 erltvllcanaagsekLkplvigkak.sprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrle..aekrkilLlldssrshetvel.les 95 
                 ++++++++a  +++  +++++i+kak + r  ++   ++ ++d+++++++++w+t++i+ eWL  +f++ ++  + +++ +L+ld+++sh t+e+   +
  EEA21940.1 204 REWVTAIEATNSTGWAIPSYIIFKAKkNVRLGWF---DDLPSDWRINISENGWTTDQIGLEWLkTHFIPYINgrSMGSYRMLILDGHGSHLTAEFdRTC 299
                 7899********************9725677888...99*********************************99*********************9*** PP

       DDE_1  96 elqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                  ++ni  +++P++s++llqPld+g+++ lK++Y +q+ q + ++ n+++k       ld+l    kA++ a + +ti+++f
  EEA21940.1 300 TENNIIPICMPPHSSHLLQPLDVGCFAVLKRHYGQQVEQRMRDGFNHIDK-------LDFLMAFPKARTeAYKARTIQNSF 373
                 **************************************************.......9**********9999999999987 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.6   0.0   4.7e-13   1.7e-09       2      61 ..      70     125 ..      69     130 .. 0.90
   2 ?   -0.8   0.2      0.43   1.6e+03      14      35 ..     483     504 ..     481     527 .. 0.78

  Alignments for each domain:
  == domain 1  score: 37.6 bits;  conditional E-value: 4.7e-13
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT.S CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh.g 61 
                  + +E++L++W+ +l++rg p++++l+re+ + l+     l++++++++k+W+ + +kR  +
   EEA21940.1  70 QSEEDSLVKWVLDLDRRGLPPRHSLVREMVNYLL-----LQHGKPQVGKNWVTNLIKRRpE 125
                  578*****************************95.....6679***************854 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.43
                  HHC-CT---SCHHHHHHHHHHH CS
  HTH_Tnp_Tc5  14 qlrergipitgelirekAqela 35 
                  q  ++ i+i + + re+Aq+l 
   EEA21940.1 483 QKSKKQISIEQGITREEAQALV 504
                  44788999999999*****996 PP

>> HTH_psq  helix-turn-helix, Psq domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.1   0.0   1.5e-09   5.3e-06       2      41 ..      16      56 ..      15      59 .. 0.93

  Alignments for each domain:
  == domain 1  score: 26.1 bits;  conditional E-value: 1.5e-09
     HTH_psq  2 pealaaAleavvnGk.mSirkAArkYgiPrsTLwrrkrgky 41
                + ++++A+ +  nG  + ir+A r+Y+iPr+TL+ r++g++
  EEA21940.1 16 EGKIQLAISDLKNGRiLNIREATRIYDIPRTTLRDRLKGIE 56
                678999****9***************************986 PP

>> zf-CCHC_2  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   1.5   3.9e-05      0.14       5      20 ..     535     550 ..     531     551 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 3.9e-05
   zf-CCHC_2   5 vChiCgkkGHyIqdCP 20 
                  C  Cg+ GH I+ CP
  EEA21940.1 535 RCSGCGVEGHRINRCP 550
                 6888************ PP

>> zf-CCHC  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   2.1   0.00017      0.62       3      18 .]     536     551 ..     534     551 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00017
                 TSSSSSSSSTTTTSTS CS
     zf-CCHC   3 CynCGepGHiardCpk 18 
                 C  CG +GH+ + Cp+
  EEA21940.1 536 CSGCGVEGHRINRCPS 551
                 777***********96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (555 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1108  (0.0617993); expected 358.6 (0.02)
Passed bias filter:                      575  (0.0320709); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.60u 0.30s 00:00:00.89 Elapsed: 00:00:00.43
# Mc/sec: 3885.21
//
Query:       EEA21941.1  [L=148]
Description: ATP synthase subunit ATP9, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    6.4e-09   36.0  12.5    1.3e-08   35.0  12.5    1.6  1  ATP-synt_C  ATP synthase subunit C
  ------ inclusion threshold ------
       0.18   12.1   4.0        5.5    7.3   2.5    2.2  2  TetR_C_11   Tetracyclin repressor-like, C-terminal domain


Domain annotation for each model (and alignments):
>> ATP-synt_C  ATP synthase subunit C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.0  12.5   1.5e-12   1.3e-08       1      59 [.      83     144 ..      83     145 .. 0.92

  Alignments for each domain:
  == domain 1  score: 35.0 bits;  conditional E-value: 1.5e-12
                 HHHHHHH.GGGHHHHHHHHHHHHHHHHHHHHSG....HHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ATP-synt_C   1 lgaglavGlsalgsGigiGkagsagiravarnp....klftksliilafaeaialygLivali 59 
                 +g g a  ++  g+G giG +++a + +varnp    +lf  +++++af+eai+l+ L++a++
  EEA21941.1  83 IGMGSAA-IGLAGAGTGIGLVFAALLHSVARNPslrgQLFAYAILGFAFVEAIGLFDLMIAMM 144
                 5677776.99999********************999999999*******************97 PP

>> TetR_C_11  Tetracyclin repressor-like, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   2.5   0.00062       5.5      14      68 ..       6      60 ..       4      78 .. 0.84
   2 ?    4.3   0.0    0.0055        49      27      49 ..      99     121 ..      89     127 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.00062
   TetR_C_11 14 llralaealaspragallrallaeaqrdpelaealrerlleprraalravlrrAv 68
                +++++a+  +s +a++++r+ +a++ + + + +  r+++ +p r+  +av r+A 
  EEA21941.1  6 FANRMATMASSSVARSAVRSQFAAVPKRTFTNAVQRTAFQAPKRTIPAAVARQAF 60
                678899999999*************999988888888999999988888877774 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.0055
   TetR_C_11  27 agallrallaeaqrdpelaealr 49 
                  g +++all+ ++r+p l+ +l 
  EEA21941.1  99 IGLVFAALLHSVARNPSLRGQLF 121
                 67799*************98775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (148 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       649  (0.0361983); expected 358.6 (0.02)
Passed bias filter:                      379  (0.0211389); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.40u 0.27s 00:00:00.67 Elapsed: 00:00:00.42
# Mc/sec: 1061.52
//
Query:       EEA21942.1  [L=400]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   4.9e-112  374.4  12.9   6.1e-112  374.1  12.9    1.0  1  Glyco_transf_15  Glycolipid 2-alpha-mannosyltransferase
      0.009   15.8   0.2      0.049   13.5   0.1    2.3  2  Imm17            Immunity protein 17


Domain annotation for each model (and alignments):
>> Glyco_transf_15  Glycolipid 2-alpha-mannosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  374.1  12.9  6.8e-116  6.1e-112      47     324 ..      43     336 ..      26     337 .. 0.92

  Alignments for each domain:
  == domain 1  score: 374.1 bits;  conditional E-value: 6.8e-116
  Glyco_transf_15  47 grkPie.dene....nAtllalvrnselakilrsikkvekrFnkkfnYpyvfindepftekfkekieklveeadvefgeipkeewsyPefidee 135
                      +++P + d n     nA+l++lvrnsel+ i+ s++ +e++Fn+kfnYp+vf nd pft++f  k++  ++ a  ++ +ipke+w+ P++id++
       EEA21942.1  43 MKQPPPtDPNTtaraNAALISLVRNSELNGIISSMRYMENSFNSKFNYPWVFFNDVPFTQEFMDKTQAETN-APCTYELIPKEHWDVPDWIDQT 135
                      333333244445677**************************************************999998.********************** PP

  Glyco_transf_15 136 kaakareelad..iaygdsesyrhmcRyysGlfykhellkkydyYwRvePdiklycdieyDvfkymkdekkiygFtlslkeieetiktlWdstk 227
                      + +ka +e+a+  ++++ + sy+ mcR+ysG+f++h++l+ky+yYwRveP++k +cdi+yDvf++m +++k ygFt+++++  ++i+tlW+ t 
       EEA21942.1 136 RMEKAFKEMANngVMHATQLSYHKMCRWYSGFFFRHPALDKYKYYWRVEPNVKYFCDIDYDVFQFMAQNNKTYGFTINIYDDPKSIPTLWPATT 229
                      ***********9********************************************************************************** PP

  Glyco_transf_15 228 kflkenkef..ieeknslsflsdddqd........tynlCeFwsnfeigdldffrseayekfFeylDskGgffYerWgdapvhsiavslllpkd 311
                       f++e +++    ++ns  +l+d+           +y++C+Fwsnfeigdldf+rs++y ++F+ylD++G ffYerWgdapvhs+a+ l++ ++
       EEA21942.1 230 AFVEERPNYalSPDENSYYWLTDSVLRpdhtkaanGYSTCHFWSNFEIGDLDFWRSQTYLDYFDYLDQTGNFFYERWGDAPVHSVALGLFAANE 323
                      *****77775245999999*988654445666677*********************************************************** PP

  Glyco_transf_15 312 kihffedigyshd 324
                      +ih+f+digy+h+
       EEA21942.1 324 QIHWFRDIGYQHS 336
                      ***********95 PP

>> Imm17  Immunity protein 17
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.1   5.4e-06     0.049       2      28 ..       9      34 ..       9      45 .. 0.80
   2 ?   -2.6   0.0       0.6   5.4e+03      30      39 ..     299     308 ..     293     310 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 5.4e-06
       Imm17  2 fvallgllsllgailnwdWfftprgak 28
                f a++gl+++l+++++  W ++++g +
  EEA21942.1  9 FAAAVGLFFILAIYFRDSW-YNSSGDR 34
                789****************.7777764 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 0.6
       Imm17  30 grfwvenfGr 39 
                 g+f++e++G+
  EEA21942.1 299 GNFFYERWGD 308
                 589***9996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (400 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       663  (0.0369792); expected 358.6 (0.02)
Passed bias filter:                      450  (0.025099); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 2803.86
//
Query:       EEA21943.1  [L=358]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.3e-111  373.0  13.0   1.5e-111  372.8  13.0    1.0  1  Glyco_transf_15  Glycolipid 2-alpha-mannosyltransferase


Domain annotation for each model (and alignments):
>> Glyco_transf_15  Glycolipid 2-alpha-mannosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  372.8  13.0  8.4e-116  1.5e-111      52     324 ..       7     294 ..       1     295 [. 0.93

  Alignments for each domain:
  == domain 1  score: 372.8 bits;  conditional E-value: 8.4e-116
  Glyco_transf_15  52 edene....nAtllalvrnselakilrsikkvekrFnkkfnYpyvfindepftekfkekieklveeadvefgeipkeewsyPefideekaakar 141
                      +d n     nA+l++lvrnsel+ i+ s++ +e++Fn+kfnYp+vf nd pft++f  k++  ++ a  ++ +ipke+w+ P++id+++ +ka 
       EEA21943.1   7 TDPNTtaraNAALISLVRNSELNGIISSMRYMENSFNSKFNYPWVFFNDVPFTQEFMDKTQAETN-APCTYELIPKEHWDVPDWIDQTRMEKAF 99 
                      333334556**************************************************999998.**************************** PP

  Glyco_transf_15 142 eelad..iaygdsesyrhmcRyysGlfykhellkkydyYwRvePdiklycdieyDvfkymkdekkiygFtlslkeieetiktlWdstkkflken 233
                      +e+a+  ++++ + sy+ mcR+ysG+f++h++l+ky+yYwRveP++k +cdi+yDvf++m +++k ygFt+++++  ++i+tlW+ t  f++e 
       EEA21943.1 100 KEMANngVMHATQLSYHKMCRWYSGFFFRHPALDKYKYYWRVEPNVKYFCDIDYDVFQFMAQNNKTYGFTINIYDDPKSIPTLWPATTAFVEER 193
                      *****9***************************************************************************************7 PP

  Glyco_transf_15 234 kef..ieeknslsflsdddqd........tynlCeFwsnfeigdldffrseayekfFeylDskGgffYerWgdapvhsiavslllpkdkihffe 317
                      +++    ++ns  +l+d+           +y++C+Fwsnfeigdldf+rs++y ++F+ylD++G ffYerWgdapvhs+a+ l++ +++ih+f+
       EEA21943.1 194 PNYalSPDENSYYWLTDSVLRpdhtkaanGYSTCHFWSNFEIGDLDFWRSQTYLDYFDYLDQTGNFFYERWGDAPVHSVALGLFAANEQIHWFR 287
                      7775245999999*988654445666677***************************************************************** PP

  Glyco_transf_15 318 digyshd 324
                      digy+h+
       EEA21943.1 288 DIGYQHS 294
                      *****95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (358 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       533  (0.0297284); expected 358.6 (0.02)
Passed bias filter:                      334  (0.018629); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.48
# Mc/sec: 2239.13
//
Query:       EEA21944.1  [L=782]
Description: TBC domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    8.3e-32  110.6   0.0    1.3e-31  109.9   0.0    1.3  1  RabGAP-TBC  Rab-GTPase-TBC domain
    2.5e-07   29.4   2.1    2.5e-07   29.4   2.1    1.8  2  SBE2        SBE2, cell-wall formation


Domain annotation for each model (and alignments):
>> RabGAP-TBC  Rab-GTPase-TBC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  109.9   0.0   1.5e-35   1.3e-31       2     215 .]     481     701 ..     480     701 .. 0.93

  Alignments for each domain:
  == domain 1  score: 109.9 bits;  conditional E-value: 1.5e-35
  RabGAP-TBC   2 elRgevWklllgyep.....evkrlkksekkqeksekeksklekseeskelsqIkkDvprtfpesesfknk.qgqnqLeriLkaysiynpevgYcqGmn 94 
                 ++Rg vW+ ++++e      +++++  ++k+ +++ +e+s+ +++++++++ +I++Dv+  fpe   f+++ ++++ L  +L ay++y+ +vgY+ G++
  EEA21944.1 481 RCRGAVWQRAINNELsltpeSYQKALLRAKDVKARGDEDSGDSSRRIREWFATISRDVSSAFPELHLFQEGgPLRDTLIDVLEAYAMYRSDVGYTYGLH 579
                 68***********98****988888889999999*****************************555555555*************************** PP

  RabGAP-TBC  95 divaplllvsldeeeaFwcfvsLlekyklrdlytsslpglkrklkvleellkkkdpklykhl.keegldlelfaikwfltlflrefpletvlrlwDlll 192
                  i+a+l l      +aF ++++ l++  +  ++t + p + r + +    l++k+p+ly+hl ++ +l+ e    + f  lf++ ++le ++r+wD+++
  EEA21944.1 580 TIAALLVLQLPTAASAFITMANALNRPLPLAFLTYDRPAIARTYGLASATLRYKFPRLYSHLyETAQLTDEEVWGPMFRSLFTNGLDLEHLSRVWDCWA 678
                 *******55557788***********************************************7779******************************766 PP

  RabGAP-TBC 193 .egekfvllrvalailklleeell 215
                  eg+++ ++rv++ail +l+ +ll
  EEA21944.1 679 fEGDRI-IIRVGVAILGCLQTQLL 701
                 599888.************99986 PP

>> SBE2  SBE2, cell-wall formation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -9.0   7.7         2   1.8e+04     222     243 ..     147     168 ..      11     235 .. 0.46
   2 !   29.4   2.1   2.8e-11   2.5e-07     445     509 ..     380     445 ..     373     455 .. 0.79

  Alignments for each domain:
  == domain 1  score: -9.0 bits;  conditional E-value: 2
        SBE2 222 sskksqssllnlrqrsraksdk 243
                  +  s+ sl+  r+rsr+ s +
  EEA21944.1 147 HGSASTPSLPHRRPRSRSVSPS 168
                 2334445555555555555544 PP

  == domain 2  score: 29.4 bits;  conditional E-value: 2.8e-11
        SBE2 445 medlilvsenkldvvshsrpswlppkdpeekklherqiskslsvasldqlek.nkdreeklikdet 509
                 m d +  s++k  v+s +rpswlppkdp e k h ++ +k + +a   + +k  k    +  kd+t
  EEA21944.1 380 MIDPLPASKEKEKVLSRTRPSWLPPKDPLEEKKHLKEYKKMMNLAKEAEKKKaAKAAAAQCEKDNT 445
                 77888899************************************9744333314445555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (782 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1037  (0.0578393); expected 358.6 (0.02)
Passed bias filter:                      567  (0.0316247); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.72u 0.30s 00:00:01.02 Elapsed: 00:00:00.44
# Mc/sec: 5374.01
//
Query:       EEA21945.1  [L=386]
Description: pre-mRNA splicing factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.8e-07   31.0   0.0      4e-07   30.4   0.0    1.3  1  HhH-GPD   HhH-GPD superfamily base excision DNA repair protei


Domain annotation for each model (and alignments):
>> HhH-GPD  HhH-GPD superfamily base excision DNA repair protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.4   0.0   2.2e-11     4e-07       2      67 ..     146     226 ..     145     298 .. 0.83

  Alignments for each domain:
  == domain 1  score: 30.4 bits;  conditional E-value: 2.2e-11
                 HHHHHTTS-HHHHHHHHHHHHHHHSHCSHHHHHHSHHHHHHHHHTTSTTHHHHHHHHHHHHHHHH.................S CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.................x RF
     HhH-GPD   2 sailsqqtsderanriierlferfgfptpedladadeekLrelirelGfyrrKakyikelArilv.................g 67 
                 ++i   +t+  +a ++  +lf+    pt ed+a+a+ e+++++ir+lGf +++a   ++lAr+ +                 +
  EEA21945.1 146 ATIFLNRTRGPVAIPVLFKLFDV--YPTIEDMASANHEDIVAIIRGLGFQNQRATKFIALARKWLesppekgkryrklnyplK 226
                 67788888888999999999999..59************************************98777777776666655551 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (386 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       445  (0.0248201); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2858.64
//
Query:       EEA21946.1  [L=892]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.3e-20   72.8   0.0    5.8e-20   71.4   0.0    1.7  1  Fungal_trans  Fungal specific transcription factor domain
      5e-09   36.1  10.8    1.2e-08   35.0  10.8    1.7  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.4   0.0   6.5e-24   5.8e-20       2     266 ..     279     662 ..     278     663 .. 0.86

  Alignments for each domain:
  == domain 1  score: 71.4 bits;  conditional E-value: 6.5e-24
  Fungal_trans   2 drffsn.........fh.pqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafpl.............. 74 
                   d++f+          +h  +++++ k  fl++       + +++sp+ll+++l+++al  +  + + +++++++    ++++l              
    EEA21946.1 279 DLYFTSafstamhpvCHhIHCYVVRKAAFLSHD------NPRNTSPALLASMLWVAALDDRAFSLSISPPKRKK----LCQFLcaltvrllrplihv 365
                   6666666666666665547889***********......******************97777666665666654....4666655556666666666 PP

  Fungal_trans  75 .......................raeili....hedfsspssslwilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkks.... 140
                                          r +++     ++ +  p+ sl  + ++ +++   ++s+ +a+ +r++  a++lar+l+L+++ +  ++ +    
    EEA21946.1 366 sfkddealpiidhqnsfslgshdRTHSFEeggdDRGLIGPAGSLDDVITYIHVASIISASEQKAASMRWWHAAFTLARELRLNQEIEATSSLNspvd 462
                   6666655555554455555555555555599999999999999999******************************************99888**** PP

  Fungal_trans 141 .........................................................lwklweeeaesrrRlwwaaFylDktialklGrpp.lldds 179
                                                                            + + +ee +e+rrR+ww  +++D+++al+++rp  lld++
    EEA21946.1 463 gsnrpfefaegtgyginhsgangnyfhpsgraslncvctrqqqrpnlmteehlqhrnGSVITEEHREERRRTWWLLYIMDRHLALCYNRPLaLLDAE 559
                   *********************************************************99************************************** PP

  Fungal_trans 180 qinlpLPcddddlwesddaseetlvetk..............lsneeksrkiasfllaLkkilskiagsllsiekqlqqrdlq..seklswveeler 260
                   + +l+LP ++  ++  d  s++ +   +              ++ +++ ++ + f l L+ i++++     + ++++  + lq  + ++ + +e+ r
    EEA21946.1 560 CDELLLPLEEGPWQAGDVHSNSSKAAGPqclvspdtnrrrcfPNFSCNDHSVFGFYLPLMAITGELINLNQAKNHPMLGTRLQvkTAWDVQANEVLR 656
                   ***********555555555555555449*************9*************************99999999999999999999999999999 PP

  Fungal_trans 261 aldnWr 266
                   +ld+++
    EEA21946.1 657 QLDTYK 662
                   999876 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.0  10.8   1.3e-12   1.2e-08       2      39 ..      43      79 ..      42      80 .. 0.89

  Alignments for each domain:
  == domain 1  score: 35.0 bits;  conditional E-value: 1.3e-12
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfysesskr 39
                aCd C+ ++v+Cd+ +P Cs+C+ ++++C+  +e++kr
  EEA21946.1 43 ACDACHTRRVRCDRAFP-CSRCVASQTQCELTRERRKR 79
                9****************.************66666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (892 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       484  (0.0269954); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.29s 00:00:00.93 Elapsed: 00:00:00.44
# Mc/sec: 6080.67
//
Query:       EEA21947.1  [L=91]
Description: 60S ribosomal protein L37a [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.4e-37  126.9   5.9    2.7e-37  126.7   5.9    1.0  1  Ribosomal_L37ae  Ribosomal L37ae protein family
  ------ inclusion threshold ------
      0.013   15.6   1.4      0.018   15.2   1.4    1.2  1  zf-RING_13       RING/Ubox like zinc-binding domain
      0.024   14.6   3.0        2.5    8.1   0.3    2.2  2  zf-FCS           MYM-type Zinc finger with FCS sequence motif
      0.025   14.6   3.2      0.044   13.8   3.2    1.5  1  Zn_Tnp_IS1595    Transposase zinc-ribbon domain
      0.028   14.7   2.3        1.2    9.5   0.2    2.1  2  C1_2             C1 domain
       0.04   13.9   0.3      0.054   13.5   0.3    1.1  1  DUF1451          Zinc-ribbon containing domain
      0.063   13.3   0.4       0.11   12.5   0.4    1.4  1  Elf1             Transcription elongation factor Elf1 like
        1.3    9.1   5.7       0.99    9.5   0.3    2.2  2  zf-BED           BED zinc finger


Domain annotation for each model (and alignments):
>> Ribosomal_L37ae  Ribosomal L37ae protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  126.7   5.9   1.2e-40   2.7e-37       1      85 []       4      88 ..       4      88 .. 0.99

  Alignments for each domain:
  == domain 1  score: 126.7 bits;  conditional E-value: 1.2e-40
                     XXXXXX-GGGGTTSS-HHHHHHHHHHHHHHHS-BEESSSSSSEEEEEETTEEEETTTTEEEE-BSSSSS-HHHHHHHH-XXXXXX CS
  Ribosomal_L37ae  1 rtkkvgiaGkygtrYGaslrkrvkkieisqhakytCpfcgktkvkRkavgiwkCkkcgktvaGgAytpettsaktvksairrlke 85
                     rt kvgi+Gkyg+rYGaslrk++k++e+ qha+ytC+fcg+++v+R +vgiw+C+ c+kt++GgAyt++t++a +++s++rrl+e
       EEA21947.1  4 RTTKVGITGKYGVRYGASLRKQLKRLEVAQHARYTCTFCGRNTVRRHSVGIWNCSGCKKTMTGGAYTLSTPAASAARSTLRRLRE 88
                     799*******************************************************************************986 PP

>> zf-RING_13  RING/Ubox like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   1.4   7.9e-06     0.018       3      40 ..      38      75 ..      36      85 .. 0.89

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 7.9e-06
                --TTTSS--SEEETTS-EE-TTTHHHTTTSS-EEESSS CS
  zf-RING_13  3 vctvcgaapvaksacggwfcgncvpyhaghchttslfa 40
                 ct cg   v + + g w c  c    +g  +t s  a
  EEA21947.1 38 TCTFCGRNTVRRHSVGIWNCSGCKKTMTGGAYTLSTPA 75
                6************************9999999988655 PP

>> zf-FCS  MYM-type Zinc finger with FCS sequence motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.2    0.0025       5.5       3      13 ..      36      46 ..      34      52 .. 0.79
   2 ?    8.1   0.3    0.0011       2.5       5      18 ..      56      69 ..      55      74 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0025
      zf-FCS  3 kkrCwfCkkyi 13
                + +C+fC+++ 
  EEA21947.1 36 RYTCTFCGRNT 46
                579*****876 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0011
      zf-FCS  5 rCwfCkkyikgkpe 18
                +C+ Ckk ++g+ +
  EEA21947.1 56 NCSGCKKTMTGGAY 69
                7*********9998 PP

>> Zn_Tnp_IS1595  Transposase zinc-ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   3.2     2e-05     0.044      18      46 .]      36      63 ..      23      63 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2e-05
  Zn_Tnp_IS1595 18 gfvCPhCgsrkayriktrglfqCkeCrkq 46
                   + +C +Cg  +++r +  g + C+ C+k+
     EEA21947.1 36 RYTCTFCGRNTVRRHSV-GIWNCSGCKKT 63
                   468*****888888886.*********85 PP

>> C1_2  C1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.1    0.0083        19      14      27 ..      32      45 ..      23      51 .. 0.77
   2 ?    9.5   0.2   0.00055       1.2      15      33 ..      51      69 ..      46      70 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0083
        C1_2 14 dssesfnCsaCgrk 27
                 ++++++C  Cgr+
  EEA21947.1 32 AQHARYTCTFCGRN 45
                56788999999987 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00055
        C1_2 15 ssesfnCsaCgrkidgffY 33
                s + +nCs+C+++++g  Y
  EEA21947.1 51 SVGIWNCSGCKKTMTGGAY 69
                56789********988777 PP

>> DUF1451  Zinc-ribbon containing domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.3   2.4e-05     0.054     108     141 ..      30      63 ..      17      64 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.4e-05
     DUF1451 108 evvglGtlvCekCgkelalkkteeippCpkCgat 141
                 ev+   +++C+ Cg+++  +++  i +C+ C++t
  EEA21947.1  30 EVAQHARYTCTFCGRNTVRRHSVGIWNCSGCKKT 63 
                 899999*************************987 PP

>> Elf1  Transcription elongation factor Elf1 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.4     5e-05      0.11      12      65 ..      26      74 ..      17      77 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 5e-05
        Elf1 12 kkkkkk.lptkFdCpfCnheksvevkldkkekiaevsCkvCgesfetkvnalsep 65
                 k+ +     +++C fC+ + +v     +++++++ +C+ C+++++  +  ls+p
  EEA21947.1 26 LKRLEVaQHARYTCTFCGRN-TV-----RRHSVGIWNCSGCKKTMTGGAYTLSTP 74
                33333337889********9.44.....57799*********9988766666655 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.3   0.00044      0.99      12      31 ..      32      51 ..      24      55 .. 0.84
   2 ?    2.6   0.7     0.062   1.4e+02      16      30 ..      54      71 ..      51      78 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00044
                GGSS--EETTTTEE----SS CS
      zf-BED 12 lkeqkavCryCgkilsrggg 31
                +++ + +C +Cg+++ r+++
  EEA21947.1 32 AQHARYTCTFCGRNTVRRHS 51
                578899**********9966 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.062
                --EETTTTEE----...S CS
      zf-BED 16 kavCryCgkilsrg...g 30
                 + C  C+k+ ++g    
  EEA21947.1 54 IWNCSGCKKTMTGGaytL 71
                689********9985543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (91 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       657  (0.0366445); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.37u 0.24s 00:00:00.61 Elapsed: 00:00:00.40
# Mc/sec: 689.32
//
Query:       EEA21948.1  [L=91]
Description: 60S ribosomal protein L37a [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.4e-37  126.9   5.9    2.7e-37  126.7   5.9    1.0  1  Ribosomal_L37ae  Ribosomal L37ae protein family
  ------ inclusion threshold ------
      0.013   15.6   1.4      0.018   15.2   1.4    1.2  1  zf-RING_13       RING/Ubox like zinc-binding domain
      0.024   14.6   3.0        2.5    8.1   0.3    2.2  2  zf-FCS           MYM-type Zinc finger with FCS sequence motif
      0.025   14.6   3.2      0.044   13.8   3.2    1.5  1  Zn_Tnp_IS1595    Transposase zinc-ribbon domain
      0.028   14.7   2.3        1.2    9.5   0.2    2.1  2  C1_2             C1 domain
       0.04   13.9   0.3      0.054   13.5   0.3    1.1  1  DUF1451          Zinc-ribbon containing domain
      0.063   13.3   0.4       0.11   12.5   0.4    1.4  1  Elf1             Transcription elongation factor Elf1 like
        1.3    9.1   5.7       0.99    9.5   0.3    2.2  2  zf-BED           BED zinc finger


Domain annotation for each model (and alignments):
>> Ribosomal_L37ae  Ribosomal L37ae protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  126.7   5.9   1.2e-40   2.7e-37       1      85 []       4      88 ..       4      88 .. 0.99

  Alignments for each domain:
  == domain 1  score: 126.7 bits;  conditional E-value: 1.2e-40
                     XXXXXX-GGGGTTSS-HHHHHHHHHHHHHHHS-BEESSSSSSEEEEEETTEEEETTTTEEEE-BSSSSS-HHHHHHHH-XXXXXX CS
  Ribosomal_L37ae  1 rtkkvgiaGkygtrYGaslrkrvkkieisqhakytCpfcgktkvkRkavgiwkCkkcgktvaGgAytpettsaktvksairrlke 85
                     rt kvgi+Gkyg+rYGaslrk++k++e+ qha+ytC+fcg+++v+R +vgiw+C+ c+kt++GgAyt++t++a +++s++rrl+e
       EEA21948.1  4 RTTKVGITGKYGVRYGASLRKQLKRLEVAQHARYTCTFCGRNTVRRHSVGIWNCSGCKKTMTGGAYTLSTPAASAARSTLRRLRE 88
                     799*******************************************************************************986 PP

>> zf-RING_13  RING/Ubox like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   1.4   7.9e-06     0.018       3      40 ..      38      75 ..      36      85 .. 0.89

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 7.9e-06
                --TTTSS--SEEETTS-EE-TTTHHHTTTSS-EEESSS CS
  zf-RING_13  3 vctvcgaapvaksacggwfcgncvpyhaghchttslfa 40
                 ct cg   v + + g w c  c    +g  +t s  a
  EEA21948.1 38 TCTFCGRNTVRRHSVGIWNCSGCKKTMTGGAYTLSTPA 75
                6************************9999999988655 PP

>> zf-FCS  MYM-type Zinc finger with FCS sequence motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.2    0.0025       5.5       3      13 ..      36      46 ..      34      52 .. 0.79
   2 ?    8.1   0.3    0.0011       2.5       5      18 ..      56      69 ..      55      74 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0025
      zf-FCS  3 kkrCwfCkkyi 13
                + +C+fC+++ 
  EEA21948.1 36 RYTCTFCGRNT 46
                579*****876 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0011
      zf-FCS  5 rCwfCkkyikgkpe 18
                +C+ Ckk ++g+ +
  EEA21948.1 56 NCSGCKKTMTGGAY 69
                7*********9998 PP

>> Zn_Tnp_IS1595  Transposase zinc-ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   3.2     2e-05     0.044      18      46 .]      36      63 ..      23      63 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2e-05
  Zn_Tnp_IS1595 18 gfvCPhCgsrkayriktrglfqCkeCrkq 46
                   + +C +Cg  +++r +  g + C+ C+k+
     EEA21948.1 36 RYTCTFCGRNTVRRHSV-GIWNCSGCKKT 63
                   468*****888888886.*********85 PP

>> C1_2  C1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.1    0.0083        19      14      27 ..      32      45 ..      23      51 .. 0.77
   2 ?    9.5   0.2   0.00055       1.2      15      33 ..      51      69 ..      46      70 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0083
        C1_2 14 dssesfnCsaCgrk 27
                 ++++++C  Cgr+
  EEA21948.1 32 AQHARYTCTFCGRN 45
                56788999999987 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00055
        C1_2 15 ssesfnCsaCgrkidgffY 33
                s + +nCs+C+++++g  Y
  EEA21948.1 51 SVGIWNCSGCKKTMTGGAY 69
                56789********988777 PP

>> DUF1451  Zinc-ribbon containing domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.3   2.4e-05     0.054     108     141 ..      30      63 ..      17      64 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.4e-05
     DUF1451 108 evvglGtlvCekCgkelalkkteeippCpkCgat 141
                 ev+   +++C+ Cg+++  +++  i +C+ C++t
  EEA21948.1  30 EVAQHARYTCTFCGRNTVRRHSVGIWNCSGCKKT 63 
                 899999*************************987 PP

>> Elf1  Transcription elongation factor Elf1 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.4     5e-05      0.11      12      65 ..      26      74 ..      17      77 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 5e-05
        Elf1 12 kkkkkk.lptkFdCpfCnheksvevkldkkekiaevsCkvCgesfetkvnalsep 65
                 k+ +     +++C fC+ + +v     +++++++ +C+ C+++++  +  ls+p
  EEA21948.1 26 LKRLEVaQHARYTCTFCGRN-TV-----RRHSVGIWNCSGCKKTMTGGAYTLSTP 74
                33333337889********9.44.....57799*********9988766666655 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.3   0.00044      0.99      12      31 ..      32      51 ..      24      55 .. 0.84
   2 ?    2.6   0.7     0.062   1.4e+02      16      30 ..      54      71 ..      51      78 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00044
                GGSS--EETTTTEE----SS CS
      zf-BED 12 lkeqkavCryCgkilsrggg 31
                +++ + +C +Cg+++ r+++
  EEA21948.1 32 AQHARYTCTFCGRNTVRRHS 51
                578899**********9966 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.062
                --EETTTTEE----...S CS
      zf-BED 16 kavCryCgkilsrg...g 30
                 + C  C+k+ ++g    
  EEA21948.1 54 IWNCSGCKKTMTGGaytL 71
                689********9985543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (91 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       657  (0.0366445); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.37u 0.28s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 673.36
//
Query:       EEA21949.1  [L=91]
Description: 60S ribosomal protein L37a [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.4e-37  126.9   5.9    2.7e-37  126.7   5.9    1.0  1  Ribosomal_L37ae  Ribosomal L37ae protein family
  ------ inclusion threshold ------
      0.013   15.6   1.4      0.018   15.2   1.4    1.2  1  zf-RING_13       RING/Ubox like zinc-binding domain
      0.024   14.6   3.0        2.5    8.1   0.3    2.2  2  zf-FCS           MYM-type Zinc finger with FCS sequence motif
      0.025   14.6   3.2      0.044   13.8   3.2    1.5  1  Zn_Tnp_IS1595    Transposase zinc-ribbon domain
      0.028   14.7   2.3        1.2    9.5   0.2    2.1  2  C1_2             C1 domain
       0.04   13.9   0.3      0.054   13.5   0.3    1.1  1  DUF1451          Zinc-ribbon containing domain
      0.063   13.3   0.4       0.11   12.5   0.4    1.4  1  Elf1             Transcription elongation factor Elf1 like
        1.3    9.1   5.7       0.99    9.5   0.3    2.2  2  zf-BED           BED zinc finger


Domain annotation for each model (and alignments):
>> Ribosomal_L37ae  Ribosomal L37ae protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  126.7   5.9   1.2e-40   2.7e-37       1      85 []       4      88 ..       4      88 .. 0.99

  Alignments for each domain:
  == domain 1  score: 126.7 bits;  conditional E-value: 1.2e-40
                     XXXXXX-GGGGTTSS-HHHHHHHHHHHHHHHS-BEESSSSSSEEEEEETTEEEETTTTEEEE-BSSSSS-HHHHHHHH-XXXXXX CS
  Ribosomal_L37ae  1 rtkkvgiaGkygtrYGaslrkrvkkieisqhakytCpfcgktkvkRkavgiwkCkkcgktvaGgAytpettsaktvksairrlke 85
                     rt kvgi+Gkyg+rYGaslrk++k++e+ qha+ytC+fcg+++v+R +vgiw+C+ c+kt++GgAyt++t++a +++s++rrl+e
       EEA21949.1  4 RTTKVGITGKYGVRYGASLRKQLKRLEVAQHARYTCTFCGRNTVRRHSVGIWNCSGCKKTMTGGAYTLSTPAASAARSTLRRLRE 88
                     799*******************************************************************************986 PP

>> zf-RING_13  RING/Ubox like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   1.4   7.9e-06     0.018       3      40 ..      38      75 ..      36      85 .. 0.89

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 7.9e-06
                --TTTSS--SEEETTS-EE-TTTHHHTTTSS-EEESSS CS
  zf-RING_13  3 vctvcgaapvaksacggwfcgncvpyhaghchttslfa 40
                 ct cg   v + + g w c  c    +g  +t s  a
  EEA21949.1 38 TCTFCGRNTVRRHSVGIWNCSGCKKTMTGGAYTLSTPA 75
                6************************9999999988655 PP

>> zf-FCS  MYM-type Zinc finger with FCS sequence motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.2    0.0025       5.5       3      13 ..      36      46 ..      34      52 .. 0.79
   2 ?    8.1   0.3    0.0011       2.5       5      18 ..      56      69 ..      55      74 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0025
      zf-FCS  3 kkrCwfCkkyi 13
                + +C+fC+++ 
  EEA21949.1 36 RYTCTFCGRNT 46
                579*****876 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0011
      zf-FCS  5 rCwfCkkyikgkpe 18
                +C+ Ckk ++g+ +
  EEA21949.1 56 NCSGCKKTMTGGAY 69
                7*********9998 PP

>> Zn_Tnp_IS1595  Transposase zinc-ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   3.2     2e-05     0.044      18      46 .]      36      63 ..      23      63 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2e-05
  Zn_Tnp_IS1595 18 gfvCPhCgsrkayriktrglfqCkeCrkq 46
                   + +C +Cg  +++r +  g + C+ C+k+
     EEA21949.1 36 RYTCTFCGRNTVRRHSV-GIWNCSGCKKT 63
                   468*****888888886.*********85 PP

>> C1_2  C1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.1    0.0083        19      14      27 ..      32      45 ..      23      51 .. 0.77
   2 ?    9.5   0.2   0.00055       1.2      15      33 ..      51      69 ..      46      70 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0083
        C1_2 14 dssesfnCsaCgrk 27
                 ++++++C  Cgr+
  EEA21949.1 32 AQHARYTCTFCGRN 45
                56788999999987 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00055
        C1_2 15 ssesfnCsaCgrkidgffY 33
                s + +nCs+C+++++g  Y
  EEA21949.1 51 SVGIWNCSGCKKTMTGGAY 69
                56789********988777 PP

>> DUF1451  Zinc-ribbon containing domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.3   2.4e-05     0.054     108     141 ..      30      63 ..      17      64 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.4e-05
     DUF1451 108 evvglGtlvCekCgkelalkkteeippCpkCgat 141
                 ev+   +++C+ Cg+++  +++  i +C+ C++t
  EEA21949.1  30 EVAQHARYTCTFCGRNTVRRHSVGIWNCSGCKKT 63 
                 899999*************************987 PP

>> Elf1  Transcription elongation factor Elf1 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.4     5e-05      0.11      12      65 ..      26      74 ..      17      77 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 5e-05
        Elf1 12 kkkkkk.lptkFdCpfCnheksvevkldkkekiaevsCkvCgesfetkvnalsep 65
                 k+ +     +++C fC+ + +v     +++++++ +C+ C+++++  +  ls+p
  EEA21949.1 26 LKRLEVaQHARYTCTFCGRN-TV-----RRHSVGIWNCSGCKKTMTGGAYTLSTP 74
                33333337889********9.44.....57799*********9988766666655 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.3   0.00044      0.99      12      31 ..      32      51 ..      24      55 .. 0.84
   2 ?    2.6   0.7     0.062   1.4e+02      16      30 ..      54      71 ..      51      78 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00044
                GGSS--EETTTTEE----SS CS
      zf-BED 12 lkeqkavCryCgkilsrggg 31
                +++ + +C +Cg+++ r+++
  EEA21949.1 32 AQHARYTCTFCGRNTVRRHS 51
                578899**********9966 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.062
                --EETTTTEE----...S CS
      zf-BED 16 kavCryCgkilsrg...g 30
                 + C  C+k+ ++g    
  EEA21949.1 54 IWNCSGCKKTMTGGaytL 71
                689********9985543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (91 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       657  (0.0366445); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.35u 0.25s 00:00:00.60 Elapsed: 00:00:00.38
# Mc/sec: 718.45
//
Query:       EEA21950.1  [L=91]
Description: 60S ribosomal protein L37a [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.4e-37  126.9   5.9    2.7e-37  126.7   5.9    1.0  1  Ribosomal_L37ae  Ribosomal L37ae protein family
  ------ inclusion threshold ------
      0.013   15.6   1.4      0.018   15.2   1.4    1.2  1  zf-RING_13       RING/Ubox like zinc-binding domain
      0.024   14.6   3.0        2.5    8.1   0.3    2.2  2  zf-FCS           MYM-type Zinc finger with FCS sequence motif
      0.025   14.6   3.2      0.044   13.8   3.2    1.5  1  Zn_Tnp_IS1595    Transposase zinc-ribbon domain
      0.028   14.7   2.3        1.2    9.5   0.2    2.1  2  C1_2             C1 domain
       0.04   13.9   0.3      0.054   13.5   0.3    1.1  1  DUF1451          Zinc-ribbon containing domain
      0.063   13.3   0.4       0.11   12.5   0.4    1.4  1  Elf1             Transcription elongation factor Elf1 like
        1.3    9.1   5.7       0.99    9.5   0.3    2.2  2  zf-BED           BED zinc finger


Domain annotation for each model (and alignments):
>> Ribosomal_L37ae  Ribosomal L37ae protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  126.7   5.9   1.2e-40   2.7e-37       1      85 []       4      88 ..       4      88 .. 0.99

  Alignments for each domain:
  == domain 1  score: 126.7 bits;  conditional E-value: 1.2e-40
                     XXXXXX-GGGGTTSS-HHHHHHHHHHHHHHHS-BEESSSSSSEEEEEETTEEEETTTTEEEE-BSSSSS-HHHHHHHH-XXXXXX CS
  Ribosomal_L37ae  1 rtkkvgiaGkygtrYGaslrkrvkkieisqhakytCpfcgktkvkRkavgiwkCkkcgktvaGgAytpettsaktvksairrlke 85
                     rt kvgi+Gkyg+rYGaslrk++k++e+ qha+ytC+fcg+++v+R +vgiw+C+ c+kt++GgAyt++t++a +++s++rrl+e
       EEA21950.1  4 RTTKVGITGKYGVRYGASLRKQLKRLEVAQHARYTCTFCGRNTVRRHSVGIWNCSGCKKTMTGGAYTLSTPAASAARSTLRRLRE 88
                     799*******************************************************************************986 PP

>> zf-RING_13  RING/Ubox like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   1.4   7.9e-06     0.018       3      40 ..      38      75 ..      36      85 .. 0.89

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 7.9e-06
                --TTTSS--SEEETTS-EE-TTTHHHTTTSS-EEESSS CS
  zf-RING_13  3 vctvcgaapvaksacggwfcgncvpyhaghchttslfa 40
                 ct cg   v + + g w c  c    +g  +t s  a
  EEA21950.1 38 TCTFCGRNTVRRHSVGIWNCSGCKKTMTGGAYTLSTPA 75
                6************************9999999988655 PP

>> zf-FCS  MYM-type Zinc finger with FCS sequence motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.2    0.0025       5.5       3      13 ..      36      46 ..      34      52 .. 0.79
   2 ?    8.1   0.3    0.0011       2.5       5      18 ..      56      69 ..      55      74 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0025
      zf-FCS  3 kkrCwfCkkyi 13
                + +C+fC+++ 
  EEA21950.1 36 RYTCTFCGRNT 46
                579*****876 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0011
      zf-FCS  5 rCwfCkkyikgkpe 18
                +C+ Ckk ++g+ +
  EEA21950.1 56 NCSGCKKTMTGGAY 69
                7*********9998 PP

>> Zn_Tnp_IS1595  Transposase zinc-ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   3.2     2e-05     0.044      18      46 .]      36      63 ..      23      63 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2e-05
  Zn_Tnp_IS1595 18 gfvCPhCgsrkayriktrglfqCkeCrkq 46
                   + +C +Cg  +++r +  g + C+ C+k+
     EEA21950.1 36 RYTCTFCGRNTVRRHSV-GIWNCSGCKKT 63
                   468*****888888886.*********85 PP

>> C1_2  C1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.1    0.0083        19      14      27 ..      32      45 ..      23      51 .. 0.77
   2 ?    9.5   0.2   0.00055       1.2      15      33 ..      51      69 ..      46      70 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0083
        C1_2 14 dssesfnCsaCgrk 27
                 ++++++C  Cgr+
  EEA21950.1 32 AQHARYTCTFCGRN 45
                56788999999987 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00055
        C1_2 15 ssesfnCsaCgrkidgffY 33
                s + +nCs+C+++++g  Y
  EEA21950.1 51 SVGIWNCSGCKKTMTGGAY 69
                56789********988777 PP

>> DUF1451  Zinc-ribbon containing domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.3   2.4e-05     0.054     108     141 ..      30      63 ..      17      64 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.4e-05
     DUF1451 108 evvglGtlvCekCgkelalkkteeippCpkCgat 141
                 ev+   +++C+ Cg+++  +++  i +C+ C++t
  EEA21950.1  30 EVAQHARYTCTFCGRNTVRRHSVGIWNCSGCKKT 63 
                 899999*************************987 PP

>> Elf1  Transcription elongation factor Elf1 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.4     5e-05      0.11      12      65 ..      26      74 ..      17      77 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 5e-05
        Elf1 12 kkkkkk.lptkFdCpfCnheksvevkldkkekiaevsCkvCgesfetkvnalsep 65
                 k+ +     +++C fC+ + +v     +++++++ +C+ C+++++  +  ls+p
  EEA21950.1 26 LKRLEVaQHARYTCTFCGRN-TV-----RRHSVGIWNCSGCKKTMTGGAYTLSTP 74
                33333337889********9.44.....57799*********9988766666655 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.3   0.00044      0.99      12      31 ..      32      51 ..      24      55 .. 0.84
   2 ?    2.6   0.7     0.062   1.4e+02      16      30 ..      54      71 ..      51      78 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00044
                GGSS--EETTTTEE----SS CS
      zf-BED 12 lkeqkavCryCgkilsrggg 31
                +++ + +C +Cg+++ r+++
  EEA21950.1 32 AQHARYTCTFCGRNTVRRHS 51
                578899**********9966 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.062
                --EETTTTEE----...S CS
      zf-BED 16 kavCryCgkilsrg...g 30
                 + C  C+k+ ++g    
  EEA21950.1 54 IWNCSGCKKTMTGGaytL 71
                689********9985543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (91 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       657  (0.0366445); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.57u 0.31s 00:00:00.87 Elapsed: 00:00:00.55
# Mc/sec: 498.50
//
Query:       EEA21951.1  [L=950]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.8e-12   45.8   0.1    1.9e-07   31.0   0.0    2.6  2  Amidohydro_3  Amidohydrolase family
    5.4e-11   42.4   0.3      3e-08   33.4   0.0    2.9  3  Amidohydro_1  Amidohydrolase family


Domain annotation for each model (and alignments):
>> Amidohydro_3  Amidohydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.9   0.1   1.3e-05      0.11       6      23 ..     159     176 ..     159     192 .. 0.77
   2 !   31.0   0.0   2.1e-11   1.9e-07     363     472 ..     437     530 ..     424     531 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 1.3e-05
  Amidohydro_3   6 kGrlvlPGFvDsHtHlag 23 
                   +G +v+PG+vD+H+H  +
    EEA21951.1 159 NGEFVTPGLVDMHSHHLA 176
                   5999***********433 PP

  == domain 2  score: 31.0 bits;  conditional E-value: 2.1e-11
  Amidohydro_3 363 llnagvkvalgsDapvgpfdpwpri.gaavmrktrrggevlrpdeelsleealalyTrgpAkalgledrkGtLevGadADlvvldadpldvdppela 458
                   l ++gv++a+ sD +v+p +++ ++   a +   +           l+   al+ +T+ pA+ l +++r G  ++G+dADlvv++a pl + ++   
    EEA21951.1 437 LAEHGVPLAFKSD-HVEPNTNARYLlSQAATAHSF----------GLPEILALQSVTSVPARSLEMHHRIGYTKPGYDADLVVWNAHPLSAGAS--- 519
                   6677777777777.666655544431222222221..........22333378889**************************************... PP

  Amidohydro_3 459 earvrltvvdGrvv 472
                      + ++++dGr++
    EEA21951.1 520 ---PLQVYIDGRPT 530
                   ...********985 PP

>> Amidohydro_1  Amidohydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.9   0.1   0.00073       6.6       1      13 [.     162     174 ..     162     195 .. 0.85
   2 !   33.4   0.0   3.3e-12     3e-08     232     341 ..     433     527 ..     349     601 .. 0.74
   3 ?   -1.8   0.0      0.17   1.5e+03     140     199 ..     768     824 ..     740     836 .. 0.68

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.00073
                   EEEE-EEEEEEEC CS
  Amidohydro_1   1 ivlPGlIDaHvHl 13 
                   +v+PGl+D+H H 
    EEA21951.1 162 FVTPGLVDMHSHH 174
                   79*********95 PP

  == domain 2  score: 33.4 bits;  conditional E-value: 3.3e-12
                   HHHHHHH.TSCEEEEEECTTSSCCGGHHHHHHHHHHHHHHCCTTTTHCHCHHHHHHHHHTHHHHHHTT-TTTSSSS-TTSB--EEEECCCTCGGGTT CS
  Amidohydro_1 232 lrkalde.GvkvglgtDgaasgnslnlleelrlalklqrgllyedeegglslkealrmaTingAkalglddkvGsievGkdADlvvvdldilaafvg 327
                   + k l e Gv  ++ +D++  + ++  l +   ++ +++         gl+   al+ +T  +A++l + +++G  ++G+dADlvv++ ++      
    EEA21951.1 433 AGKILAEhGVPLAFKSDHVEPNTNARYLLS---QAATAH-------SFGLPEILALQSVTSVPARSLEMHHRIGYTKPGYDADLVVWNAHP------ 513
                   45566666999******9977777733222...222223.......789**************************************6644...... PP

                   TCTSEEEEEEEETT CS
  Amidohydro_1 328 lkkdgnvkkvivkG 341
                   l+   ++ +v+++G
    EEA21951.1 514 LSAGASPLQVYIDG 527
                   22233344444444 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 0.17
                   HHHHHTTEEEEEETSSCHHHHHHHHHHTTTEEEETTTTSTCCHHTTTHCCEEEHCTCEEE CS
  Amidohydro_1 140 eakkrdlpvaiHaletkgevedaeaafgetiehgthlevaeslglldeiklilahgvhlt 199
                   +a++ ++ v++H+ e+k+++ ++++  ++  + +  +++   + ++ +++ i+a g +l 
    EEA21951.1 768 KAADGKITVVVHT-ENKYDILQIVKIKKDYPKAKLVVYG--AAEAPSVANEIAAAGLPLI 824
                   6888899999999.6666665666666655566444444..4458888888888888775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (950 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       389  (0.0216967); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.77u 0.35s 00:00:01.12 Elapsed: 00:00:00.53
# Mc/sec: 5404.74
//
Query:       EEA21952.1  [L=1122]
Description: Na/K ATPase alpha 1 subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.8e-42  144.5   4.7    2.8e-42  144.5   4.7    2.4  3  Cation_ATPase_C  Cation transporting ATPase, C-terminus
    2.3e-37  128.3   3.2    2.3e-37  128.3   3.2    2.3  2  E1-E2_ATPase     E1-E2 ATPase
    1.6e-19   69.8   0.0      3e-19   68.9   0.0    1.5  1  Cation_ATPase    Cation transport ATPase (P-type)
    2.7e-18   67.1   0.0    4.3e-09   37.0   0.0    2.8  2  Hydrolase        haloacid dehalogenase-like hydrolase
    4.1e-13   48.8   0.0      1e-12   47.5   0.0    1.8  1  Cation_ATPase_N  Cation transporter/ATPase, N-terminus
     0.0047   16.7   0.3     0.0098   15.7   0.3    1.5  1  Hydrolase_3      haloacid dehalogenase-like hydrolase
  ------ inclusion threshold ------
        1.2    9.0   6.4        2.5    7.9   0.2    3.2  3  DUF2157          Predicted membrane protein (DUF2157)
        8.3    6.1   8.9        2.5    7.8   0.9    3.1  3  FtsK_4TM         4TM region of DNA translocase FtsK/SpoIIIE


Domain annotation for each model (and alignments):
>> Cation_ATPase_C  Cation transporting ATPase, C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.4       2.2   4.9e+03     160     160 ..     206     206 ..     171     232 .. 0.50
   2 ?   -1.3   0.2      0.66   1.5e+03      60      79 ..     371     390 ..     346     435 .. 0.64
   3 !  144.5   4.7   1.2e-45   2.8e-42       1     181 [.     902    1107 ..     902    1108 .. 0.96

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 2.2
  Cation_ATPase_C 160 e 160
                      +
       EEA21952.1 206 Y 206
                      1 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.66
  Cation_ATPase_C  60 lqalvtllvffltlllfgis 79 
                      + ++v+l+vf+++lllf + 
       EEA21952.1 371 VKIIVCLTVFLAALLLFTWV 390
                      23333333333333333222 PP

  == domain 3  score: 144.5 bits;  conditional E-value: 1.2e-45
  Cation_ATPase_C    1 plplsaiqiLwinLvtDllpalaLaleppekdimkrpPr.kkkepliskkmlrri.liqgllqalvtllvffltll................ 74  
                       plpls+ ++++i ++tDl+++l+L +e++e d+++ pPr ++k++li+ k+++++ l++g++ ++++ ++ffl+++                
       EEA21952.1  902 PLPLSSFLMIIICVFTDLFLSLSLIMEQEEFDLLDLPPRnHRKDHLINLKVYIQSyLFIGVMETICAHAMFFLYFYkhagipfhalifafes 993 
                       89**************************************************************************9999999998888888 PP

  Cation_ATPase_C   75 ....lfgisekenklssnyaqtmaFitlvlsqifnalnlrsrreslfkfsglf...snkllllaillslllqvlivyvpglnavfgtaplsl 159 
                           ++g++++e  + + ++q+++Fitl ++q+ n+l++r +r s++++  ++   +n++ll ++++sl+++v+++  pgl+++f+ta+ ++
       EEA21952.1  994 ysdgFYGYTADELTHFNTVGQSVYFITLLFLQWGNILSVRNKRLSILQADPIRkerRNPWLLASAIISLAIAVFVTEEPGLQQIFQTASAPI 1085
                       8887668888887777*************************************9999*********************************** PP

  Cation_ATPase_C  160 eewlialllalvvllvdelvKl 181 
                       e w++ ++la+ +ll+de++Kl
       EEA21952.1 1086 EFWFYPIPLAVGILLMDEIRKL 1107
                       *********************8 PP

>> E1-E2_ATPase  E1-E2 ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1      0.64   1.4e+03     124     157 ..     181     215 ..     163     237 .. 0.60
   2 !  128.3   3.2     1e-40   2.3e-37       2     180 ..     242     439 ..     241     440 .. 0.95

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.64
                   HHHHHHHHHHHHS-STTTSSTTHHHHH.HHHHHHH CS
  E1-E2_ATPase 124 pvvlliallvflialllgkslaeallr.alallva 157
                   + vl+i++++f+i +   ++++   ++ +l++lv 
    EEA21952.1 181 CSVLWIGVIIFFICWRPLGDPNPQPYNlGLGILVL 215
                   34556666666666565566664444444444443 PP

  == domain 2  score: 128.3 bits;  conditional E-value: 1e-40
                   SS--EEEEE-TTS-EEEEGGG--TTSEEEEETT-B--SEEEEEEE-S..EEE-TTTS---S-EE-..........G-TTEE-TT-EEEE-EEEEEEE CS
  E1-E2_ATPase   2 llpptakvirdgteeeidakelvpGDivllkagdrvpaDgrivegsa..evdesaLTGEslpvek..........ekgdmvfsGtvvvsgeakavVt 86 
                   llp++a  +r+g+ +++++++lv+GDiv++  g++vpaD+r++  s   ++d s+LTGEs+ ve           e+++ +++Gt v++g+a++vV+
    EEA21952.1 242 LLPAEALAVRSGQSVRVPSSNLVVGDIVKISIGNKVPADMRLLTTSGdvRFDRSMLTGESEEVEGvtnmtdenflETRNIAMMGTLVTNGTATGVVV 338
                   78999***************************************99989*************************99********************* PP

                   E-TTTSTTTTTSTTS--------HHHHHHHHHHHHHHHHHHHHHHHHHHS-STTTSSTT.......HHHHHHHHHHHHHS-TTHHHHHHHHHHHHHH CS
  E1-E2_ATPase  87 atgedtelgkiarlveeakskktplqkkldklgkvlvpvvlliallvflialllgksla.......eallralallvaaiPcaLplavplalalgar 176
                    tg+d+ +g+ia  + + ks+ t +q ++++++k++v++ +++a+l++++++ + ++         ++l  +++ +va+iP+++p+ v l+l++ ar
    EEA21952.1 339 LTGKDSVMGHIALTTTSVKSQPTLIQLEISRFVKIIVCLTVFLAALLLFTWVGWLRKDHaafmnvvDMLDDVMGCVVAFIPEGMPVGVALTLMMIAR 435
                   ********************************************99999999876666657888877777799999********************* PP

                   HHHH CS
  E1-E2_ATPase 177 rlak 180
                   r+++
    EEA21952.1 436 RMKD 439
                   **86 PP

>> Cation_ATPase  Cation transport ATPase (P-type)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.9   0.0   1.4e-22     3e-19       2      91 .]     510     617 ..     509     617 .. 0.97

  Alignments for each domain:
  == domain 1  score: 68.9 bits;  conditional E-value: 1.4e-22
  Cation_ATPase   2 lcNsaaf...sensekdevkllGnktEsALlvlaekl.gldteelreetkkvqeipFnssrKrmsvvlkle..............pekkvrlyvKG 79 
                    +cN+ +f   + n++  ++ + Gn+t+ A l+++e +   ++++lr+ +++v+ ipFnss+K+m++++k+e              +  +++l+vKG
     EEA21952.1 510 ICNDGTFeatTLNMPAMDRLVQGNATDGASLKFVESVeDGSCQRLRDANPRVFAIPFNSSNKWMLTLHKTEssmekghenqieaiDRPNFLLIVKG 605
                    799999999999*************************8899******************************************************* PP

  Cation_ATPase  80 ApeiilkrCthv 91 
                    A++i+l +Cth+
     EEA21952.1 606 ASDILLPHCTHY 617
                    **********95 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.0   0.0   1.9e-12   4.3e-09       1     162 [.     456     734 ..     456     747 .. 0.74
   2 !   26.7   0.0   2.6e-09   5.8e-06     161     210 .]     784     833 ..     771     833 .. 0.83

  Alignments for each domain:
  == domain 1  score: 37.0 bits;  conditional E-value: 1.9e-12
                 SSEEEEESBTTTBCHH.HHHHHHHHHH...CHHHHHHHHHHHHCHHHHHHHHHHHHH..............HHHHHHHHHETTTE.............. CS
                 xxxxxxxxxxxxxxxx.xxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxx..............xxxxxxxxxxxxxx.............. RF
   Hydrolase   1 iktvvfDkdGTLttge.psvedvivsa...alalaaaletgsehpigkalvaaakar..............sgaltgfatfigrg.............. 67 
                 +++++ Dk+GTLt+ +  +v++++v     a + a+a +t+++ pi + l aaa                    ++g+                     
  EEA21952.1 456 VNVICSDKTGTLTENRmTVVTTAFVDErmsAADAAVASRTSNTEPIRELLKAAAICNdgtfeattlnmpamDRLVQGN------Atdgaslkfvesved 548
                 699**********99955555555555577777777777779999999995555444376555544444432222222......144455666666666 PP

                 ...............HHHHTHHHHHHHH..HCHHHHHHHHHHHHHHCHHHHHH.............................................. CS
                 ...............xxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxx.............................................. RF
   Hydrolase  68 ...............ayaigkpewltal..dippdlgaaigsaqsqgrtvall.............................................. 103
                                     + +w+  l  + ++  +    + ++ +r  +ll                                              
  EEA21952.1 549 gscqrlrdanprvfaIPFNSSNKWMLTLhkTESSMEKGHENQIEAIDRPNFLLivkgasdillphcthywsykqnsiqtldddaklqlatlqekmsrna 647
                 678866666666555334444446666644444444444444444444444449999999999999999999999999999999999************ PP

                 ................................TTHHHHHHHHHHTHHBHTTHHHHHHHHHHTTEEEEEEESSEHHHHHHHHHHTTGGGESE CS
                 ................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase 104 ................................qaralavftiadplkvkpeaaeavasLkaagievvlltgdnpetaeraanqlGddyfda 162
                                                 +  + +++ i dp  +++e+a +vas ++agi+  ++tgd   t  ++a+ +G  +f++
  EEA21952.1 648 ervimlcqrtvtpretlgsnafsdeireeglsDLTLIGLLGIVDP--PRKETASTVASCRRAGIRFLMVTGDLGLTGAAIARDVG--IFSG 734
                 *******************************999***********..**************************************..4332 PP

  == domain 2  score: 26.7 bits;  conditional E-value: 2.6e-09
                 SEEEEHHCESSTTTSHHHHHHHHHHHTSTGGGEEEEESSHHHHHHHHHTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase 161 daviasdietvakpspegkvaaireLqgkpeevamVGDgvnDaaalaaAg 210
                 d++ ++ + +++   pe+k+++++e++ +   va+ GDgvnDa+a++aA+
  EEA21952.1 784 DVICGYQEIVFGRTMPEQKLRIVNEFRSRNYVVAVTGDGVNDAPAMRAAD 833
                 4444455555999**************99999*****************8 PP

>> Cation_ATPase_N  Cation transporter/ATPase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.5   0.0   4.6e-16     1e-12       1      68 [.     124     190 ..     124     191 .. 0.97

  Alignments for each domain:
  == domain 1  score: 47.5 bits;  conditional E-value: 4.6e-16
  Cation_ATPase_N   1 ehalsleevlekLetdlenGLtqaeaaerlkkyGpNelkekkkkslwvkllkqftnplvilLlvaalv 68 
                      +h+l++e ++++L++++ +GL+ +eaaerl+++GpN+l + ++++++ kll  +   +  +L++++++
       EEA21952.1 124 FHSLPPELLCKQLGVSDADGLSPSEAAERLARHGPNAL-PHRRENYILKLLTYVFGGFCSVLWIGVII 190
                      599***********************************.999**********************9997 PP

>> Hydrolase_3  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.3   4.4e-06    0.0098     204     245 ..     814     855 ..     803     864 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 4.4e-06
                  GGEEEEESSGGGHHHHHHSSEEEEETTS-HHHHHHSSEEE-- CS
  Hydrolase_3 204 eeviafGDgeNDieMLeaaglgvAmgnaseevkkaAdyvtks 245
                    v++ GDg ND + + aa++g+A+ ++s+ + +aAd v  +
   EEA21952.1 814 YVVAVTGDGVNDAPAMRAADVGIAVVSGSDVALEAADLVLMD 855
                  557889*******************************99765 PP

>> DUF2157  Predicted membrane protein (DUF2157)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.1      0.44   9.8e+02      73      85 ..     183     195 ..     141     252 .. 0.49
   2 ?    7.9   0.2    0.0011       2.5      60      88 ..     366     395 ..     365     456 .. 0.82
   3 ?    2.5   0.3      0.05   1.1e+02      88     128 ..    1035    1089 ..     962    1102 .. 0.76

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.44
     DUF2157  73 llllslllgavlw 85 
                 +l++ +++ ++ w
  EEA21952.1 183 VLWIGVIIFFICW 195
                 2222222223333 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0011
     DUF2157  60 glsrlvkfllllvllllslllg.avlwrdr 88 
                 ++sr+vk++++l+++l++lll  +v w ++
  EEA21952.1 366 EISRFVKIIVCLTVFLAALLLFtWVGWLRK 395
                 69*************************965 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.05
     DUF2157   88 r..............rvpprlgeallllaalllgaaialvgqifqlsgdayslll 128 
                  +              r+p +l+ a++ la  ++++     +qifq+ + + ++ +
  EEA21952.1 1035 KrlsilqadpirkerRNPWLLASAIISLAIAVFVTEEPGLQQIFQTASAPIEFWF 1089
                  246667777777776888889999999*******************998776653 PP

>> FtsK_4TM  4TM region of DNA translocase FtsK/SpoIIIE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   0.9    0.0011       2.5      55     110 ..     170     227 ..     167     239 .. 0.80
   2 ?   -2.1   0.5       1.2   2.7e+03     144     164 ..     373     393 ..     367     408 .. 0.66
   3 ?    2.1   0.0     0.062   1.4e+02      59     102 ..    1009    1065 ..    1000    1082 .. 0.58

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0011
    FtsK_4TM  55 adlllslfG..lsawllvvlllawglrllrrkslerrllrllgalllllasaalfalr 110
                   ll ++fG   s++++ v+++++++r l + ++++ +l l  ++l+++ + a f+ +
  EEA21952.1 170 LKLLTYVFGgfCSVLWIGVIIFFICWRPLGDPNPQPYNLGLGILVLIVIFLQAAFSAF 227
                 5678888885558889999999***************999999999999998888743 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.2
    FtsK_4TM 144 tllllvllliglslvlgfswl 164
                 ++++l ++l++l+l++ + wl
  EEA21952.1 373 IIVCLTVFLAALLLFTWVGWL 393
                 455555666666665555554 PP

  == domain 3  score: 2.1 bits;  conditional E-value: 0.062
    FtsK_4TM   59 lslfGlsawllvvlllawg.lrllrr............kslerrllrllgallllla 102 
                  + ++G s++++ +l+l wg + ++r+            k+ ++++l + +++ l++a
  EEA21952.1 1009 FNTVGQSVYFITLLFLQWGnILSVRNkrlsilqadpirKERRNPWLLASAIISLAIA 1065
                  4689***************54444444555555444322222223333333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1122 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       669  (0.0373138); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.86u 0.29s 00:00:01.14 Elapsed: 00:00:00.51
# Mc/sec: 6677.79
//
Query:       EEA21953.1  [L=419]
Description: serine/threonine-protein kinase hal4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.5e-44  150.8   0.0      7e-44  150.2   0.0    1.2  1  Pkinase      Protein kinase domain
    1.4e-23   83.5   0.1    6.5e-23   81.3   0.1    1.9  1  Pkinase_Tyr  Protein tyrosine kinase
      6e-07   29.1   0.0    1.7e-06   27.5   0.0    1.6  1  Kinase-like  Kinase-like
     0.0057   16.0   0.1      0.011   15.1   0.1    1.4  1  Kdo          Lipopolysaccharide kinase (Kdo/WaaP) family


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  150.2   0.0   1.6e-47     7e-44      20     264 .]     145     403 ..     140     403 .. 0.89

  Alignments for each domain:
  == domain 1  score: 150.2 bits;  conditional E-value: 1.6e-47
                 ETTTTEEEEEEEEECHCHCHHHH..HHHHHHHHHHHHHSCTTB--EEEEEEE.SSEEEEEEE--TTEBHHHHHHHHSS--HHHHHHHHHHHHHHHHHHH CS
     Pkinase  20 eketgkivAvKkikkekakkkke..kkvlrEikilkklkhpnivrlyevfee.kdelylvleyveggeladllerkgslseeeakkiakqilegleylH 115
                 +++t+k ++vK++ +  ++  k   ++v++E  i ++l+hpn+vr++e + + + +l+ v+ey++ g+l +l+e+  +l+++ea  ++kq+l++++y+H
  EEA21953.1 145 KATTKKLYVVKIFVHPLRNGFKSytRRVTTEFCIAHTLQHPNVVRVIELLPNeHGDLCQVMEYCDAGSLLNLIEQVNKLTHDEADCFLKQVLHAVQYIH 243
                 4679999****999887777666779**********************99764899*******************99********************** PP

                 HTTEE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCS................BCTTTSCGGGS-HHHHTTSCB.SHHHHHHHHHHHHHHHHHSS-ST CS
     Pkinase 116 skgiiHrDlKpeNiLidekgelKitDFGlakelesssk................ltsfvgtseYlAPEvlkeney.skkvDvWslGvilyelltgkppf 197
                 s g+ Hr lKpeNiL+ ++g lKitDF  a+ ++                     ++  gt  Y+APE  +++ +  ++ D+W++G++ + + +g+ p+
  EEA21953.1 244 SVGVSHRNLKPENILLTRRGTLKITDFCCAECFRLPWVappalkqsppeivsahQQDLKGTIAYMAPEQFGKTAFdPAAGDMWAVGIVYFAMRSGRLPW 342
                 *******************************999866678899999*******999*******************56678******************* PP

                 TTSSHHHHHHHHHHTHHHHHHHCTSHH...HHHTTS-HHHHHHHHHHT-SSGCCSTTHHHHHTSGGG CS
     Pkinase 198 sgekgkekvekeldqlekilkilgetkeklpeaseiseeakdllkkllkkdpkkRltaeellqhpyl 264
                 + ++++++ ++ +++       l++ + +   +    e+ +d l ++l+ +p++R ta+++l+++++
  EEA21953.1 343 KRSTNEDSLYRTYTR------DLEHGRGNKYLDLVAGETRRDTLYSILQPNPRNRSTATQALDSEWI 403
                 *76666644444444......4555455555555569999*************************97 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.3   0.1   1.5e-26   6.5e-23      27     216 ..     152     352 ..     136     394 .. 0.81

  Alignments for each domain:
  == domain 1  score: 81.3 bits;  conditional E-value: 1.5e-26
                  SEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS-BTTB--EEEEEE.SSSSEEEEEE--TTEBHHHHHHHTCTTTSBHHHHHHHHHHHHHHHHHHHHTT CS
  Pkinase_Tyr  27 kevkVavKtlkeeateeekeelleeakimkklkhpnivkllgvct.keepllivteyvkgGdLlkfLrkkekekltlkdllsfalqvAkGmeyLeskk 123
                    vk+ v  l+++ ++  ++++++e  i ++l+hpn+v+++ +   +++ l+ v+ey++ G+Ll+ +++   +klt ++  +f  qv ++++y++s  
   EEA21953.1 152 YVVKIFVHPLRNGFKSY-TRRVTTEFCIAHTLQHPNVVRVIELLPnEHGDLCQVMEYCDAGSLLNLIEQV--NKLTHDEADCFLKQVLHAVQYIHSVG 246
                  44556666666666666.89999********************9977888*****************998..9************************* PP

                  EEEST-SGGGEEEEETTEEEE-STTTHE..........ETTTSSEE......EETTSSTSGGGGS-HHHHHHSEEEH.HHHHHHHHHHHHHHHTTSSG CS
  Pkinase_Tyr 124 lvHrdlaarNvLlsenkvvkisDfGLar..........diekddey......vkkeeaklpvkWmapEslkekkfts.ksDvWsfGvllwEiftlges 204
                  + Hr+l   N+Ll+++ + ki+Df  a+          ++++           ++++ k  + +mapE + ++ f   + D+W+ G++ + + + g+ 
   EEA21953.1 247 VSHRNLKPENILLTRRGTLKITDFCCAEcfrlpwvappALKQ---SppeivsAHQQDLKGTIAYMAPEQFGKTAFDPaAGDMWAVGIVYFAMRS-GRL 340
                  ************************998722222221111212...1233444667778899**************96156**********9988.*** PP

                  TTTTSHHHHHHH CS
  Pkinase_Tyr 205 pypglkneevle 216
                  p+++ +ne+ l 
   EEA21953.1 341 PWKRSTNEDSLY 352
                  ***998887544 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.5   0.0   3.9e-10   1.7e-06     114     256 ..     191     348 ..     181     357 .. 0.70

  Alignments for each domain:
  == domain 1  score: 27.5 bits;  conditional E-value: 3.9e-10
  Kinase-like 114 llllpaasvdl.........eilnkvlqkrsethkkletiarlllTlqlirlaanLqakglvhgkftvdnllldekgglmlggftaLvragtkvvlse 202
                  ++llp+ + dl         +   ++l+  ++ +k   + a   l  q++  ++++++ g+ h +++++n+ll ++g l++++f          v + 
   EEA21953.1 191 IELLPNEHGDLcqvmeycdaG---SLLNLIEQVNKLTHDEADCFL-KQVLHAVQYIHSVGVSHRNLKPENILLTRRGTLKITDFCCAECFRLPWV-AP 283
                  556666666664444332222...233333333444444555566.688899********************************97766666666.77 PP

  Kinase-like 203 vekgfaPpEllgsrgg.......ytrknktkmt.h...kldaWqlGlviyriwclklPltlatee 256
                   +   +PpE+++++++       y   ++   t +   + d W++G+v + + +  lP    t+e
   EEA21953.1 284 PALKQSPPEIVSAHQQdlkgtiaYMAPEQFGKTaFdpaAGDMWAVGIVYFAMRSGRLPWKRSTNE 348
                  778889****9997665566677665444333312222679*****************9988776 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.1   2.4e-06     0.011     104     155 ..     212     263 ..     204     273 .. 0.85

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 2.4e-06
         Kdo 104 dLedllakwaelaeelkrallkavgrliaklhragvnHadlyaknillqqee 155
                 +L +l+++ ++l +      lk+v  +++ +h++gv H+ l + nill  ++
  EEA21953.1 212 SLLNLIEQVNKLTHDEADCFLKQVLHAVQYIHSVGVSHRNLKPENILLTRRG 263
                 67777777777888889999****************************9887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (419 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       618  (0.0344693); expected 358.6 (0.02)
Passed bias filter:                      514  (0.0286686); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.24s 00:00:00.77 Elapsed: 00:00:00.41
# Mc/sec: 3060.87
//
Query:       EEA21954.1  [L=1332]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.7e-22   79.2   0.0    1.6e-08   35.0   0.1    5.3  5  Ank_2       Ankyrin repeats (3 copies)
    1.4e-15   57.4   0.1    2.8e-05   24.6   0.0    6.6  7  Ank_4       Ankyrin repeats (many copies)
    1.2e-14   54.1   0.5    3.4e-06   27.2   0.1    4.9  4  Ank_5       Ankyrin repeats (many copies)
    2.3e-10   40.5   4.0     0.0036   17.7   0.0    6.8  6  Ank         Ankyrin repeat
    1.3e-09   37.5   0.0      0.053   14.1   0.0    7.6  7  Ank_3       Ankyrin repeat
    7.3e-09   35.2   0.0    1.8e-08   33.9   0.0    1.6  1  PNP_UDP_1   Phosphorylase superfamily
     0.0098   15.2   0.0       0.04   13.2   0.0    1.9  2  KAP_NTPase  KAP family P-loop domain


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0     0.017        45      27      74 ..     910     964 ..     860     977 .. 0.67
   2 !    7.0   0.0    0.0034       8.8      26      67 ..    1009    1056 ..     988    1062 .. 0.78
   3 !   35.0   0.1   6.2e-12   1.6e-08      10      79 ..    1061    1142 ..    1055    1145 .. 0.83
   4 !   25.6   0.0   5.6e-09   1.4e-05       8      79 ..    1160    1246 ..    1151    1250 .. 0.73
   5 ?   -3.4   0.0       6.1   1.6e+04      65      75 ..    1273    1282 ..    1253    1290 .. 0.66

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.017
       Ank_2  27 ktaLhyAakngnleivklLleh.....ad.....ndgrtpLhyAarsghleivklLle 74 
                 ++ + y a+ g++ i++ +le       d     n   +pL yA+ s    +v+lLle
  EEA21954.1 910 RNLISYLAEFGDTVILRKMLETreykkCDyrtylNGPVNPLLYAS-SE--AVVELLLE 964
                 666777788887777788887334455223345444558888887.33..68888885 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0034
       Ank_2   26 gktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghle 67  
                  g++ L yAa++g + ++++  ++       ++  g+tp  +Aa +g+++
  EEA21954.1 1009 GQSFLAYAAERGFERLARAAFQKvdydvneTNVLGQTPFSLAA-QGRIN 1056
                  689999******9999999998756564344466********9.67655 PP

  == domain 3  score: 35.0 bits;  conditional E-value: 6.2e-12
       Ank_2   10 lelvklLl.egadpn..k.ngktaLhyAakng.nleivklLle.h......adndgrtpLhyAarsghleivklLlekgadi 79  
                  l +++ L+ ++a+pn  +  g+t+LhyA+    n+e++++L++ h       d +g t+L  A+ +++   +++Ll  gad+
  EEA21954.1 1061 LAIMNSLHeAHANPNtpDkYGRTPLHYAVLTPfNEEVIQFLVSiHdvnlenKDHQGLTALASAVLENRKGYIQILLAAGADP 1142
                  5688999988899998636***********8645699*****9757555445588*********************99*997 PP

  == domain 4  score: 25.6 bits;  conditional E-value: 5.6e-09
       Ank_2    8 gnlelvklLl..egadpn..k.ngktaLhyAakngnl...eivklLleh.......adndgrtpLhyAarsghleivklLlekgadi 79  
                  gn   + lL     +d++  +  g+taL ++a  g++   +++++Lle         dn+grt+L  A++  ++ +v +L+    ++
  EEA21954.1 1160 GNMGSFSLLFgdPRFDLDavDlYGRTALSWCATVGDEvaaKMMSMLLESetvdpnlRDNEGRTALERAICAAQPTMVSILCSPTQSL 1246
                  54446777774444666665489******99999965333569****95676666555*************999******9655555 PP

  == domain 5  score: -3.4 bits;  conditional E-value: 6.1
       Ank_2   65 hleivklLlek 75  
                  h ei++lLl +
  EEA21954.1 1273 H-EIARLLLAS 1282
                  2.555555544 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       2.8   7.1e+03      11      28 ..     953     970 ..     950     977 .. 0.79
   2 !    6.2   0.0    0.0065        17       5      44 ..    1013    1052 ..    1011    1058 .. 0.89
   3 !   24.6   0.0   1.1e-08   2.8e-05      11      55 .]    1058    1102 ..    1048    1102 .. 0.90
   4 !    7.9   0.0    0.0018       4.6      12      55 .]    1093    1136 ..    1091    1138 .. 0.84
   5 !    7.8   0.0    0.0019         5       2      52 ..    1117    1166 ..    1116    1169 .. 0.85
   6 ?    5.5   0.0      0.01        26       9      43 ..    1157    1191 ..    1149    1201 .. 0.84
   7 !    7.4   0.0    0.0027       6.8      16      44 ..    1201    1229 ..    1199    1239 .. 0.80

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 2.8
       Ank_4  11 sgrlelvrlLlekgadin 28 
                 ++ + +v+lLle+ +d++
  EEA21954.1 953 ASSEAVVELLLEFAQDLH 970
                 67888999***9988876 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.0065
       Ank_4    5 LhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAak 44  
                  L yaa+ g ++l+r  ++k + d+n++ n  G+t++  Aa+
  EEA21954.1 1013 LAYAAERGFERLARAAFQKvDYDVNET-NVLGQTPFSLAAQ 1052
                  568999999********99999*****.********99986 PP

  == domain 3  score: 24.6 bits;  conditional E-value: 1.1e-08
       Ank_4   11 sgrlelvrlLlekgadinaqdnrsGetalhiAakrg.nveilklLl 55  
                  +grl +  +L+e  a++n   +++G+t+lh+A+++  n e++++L+
  EEA21954.1 1058 AGRLAIMNSLHEAHANPNTP-DKYGRTPLHYAVLTPfNEEVIQFLV 1102
                  899****************8.**************99999999996 PP

  == domain 4  score: 7.9 bits;  conditional E-value: 0.0018
       Ank_4   12 grlelvrlLle.kgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  +++e++++L++ +++++    + +G+tal  A++ +++ +++ Ll
  EEA21954.1 1093 FNEEVIQFLVSiHDVNLENK-DHQGLTALASAVLENRKGYIQILL 1136
                  5899******7689999887.************777777666665 PP

  == domain 5  score: 7.8 bits;  conditional E-value: 0.0019
       Ank_4    2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilk 52  
                  ltaL +a+ ++r  ++++Ll+ gad+  ++++ G t l++ +k+gn   + 
  EEA21954.1 1117 LTALASAVLENRKGYIQILLAAGADPMPRLPD-GSTMLIYNVKKGNMGSFS 1166
                  799999*******************7777788.999999999999865555 PP

  == domain 6  score: 5.5 bits;  conditional E-value: 0.01
       Ank_4    9 aisgrlelvrlLlek.gadinaqdnrsGetalhiAa 43  
                  +++g++ +  lL+   + d++a+ + +G+tal  +a
  EEA21954.1 1157 VKKGNMGSFSLLFGDpRFDLDAV-DLYGRTALSWCA 1191
                  559999999****999*******.*******96665 PP

  == domain 7  score: 7.4 bits;  conditional E-value: 0.0027
       Ank_4   16 lvrlLlek.gadinaqdnrsGetalhiAak 44  
                  +   Lle+  +d+n + +++G+tal +A+ 
  EEA21954.1 1201 MMSMLLESeTVDPNLR-DNEGRTALERAIC 1229
                  6778999978******.999*****88875 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.0      0.13   3.3e+02      20      56 .]    1013    1050 ..    1008    1050 .. 0.89
   2 !   27.2   0.1   1.3e-09   3.4e-06       1      53 [.    1067    1120 ..    1067    1123 .. 0.94
   3 !    6.5   0.0    0.0041        11       1      53 [.    1135    1187 ..    1135    1188 .. 0.83
   4 !   12.3   0.0   6.5e-05      0.17       5      52 ..    1209    1256 ..    1198    1259 .. 0.81

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.13
       Ank_5   20 LhvAakygaadvvrlLl.argadlnltdsrGltaldlA 56  
                  L +Aa++g  +++r  + +   d n t+  G+t++ lA
  EEA21954.1 1013 LAYAAERGFERLARAAFqKVDYDVNETNVLGQTPFSLA 1050
                  788999999999999999999*************9987 PP

  == domain 2  score: 27.2 bits;  conditional E-value: 1.3e-09
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl..argadlnltdsrGltal 53  
                  L+e+  a++n++d++g tpLh+A+     + v+ +l   + ++l  +d +Gltal
  EEA21954.1 1067 LHEAH-ANPNTPDKYGRTPLHYAVLTPFNEEVIQFLvsIHDVNLENKDHQGLTAL 1120
                  56665.************************************************8 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.0041
       Ank_5    1 Llehg.padvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltal 53  
                  Ll++g +  +    ++g t L++ +k+g+   + lL+ +++ dl++ d +G+tal
  EEA21954.1 1135 LLAAGaDPMPRL--PDGSTMLIYNVKKGNMGSFSLLFgDPRFDLDAVDLYGRTAL 1187
                  666773344444..4566************************************8 PP

  == domain 4  score: 12.3 bits;  conditional E-value: 6.5e-05
       Ank_5    5 gpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGlta 52  
                    +d+n +d++g t+L  A+ +  +++v +L+ + ++l+l++s G+++
  EEA21954.1 1209 ETVDPNLRDNEGRTALERAICAAQPTMVSILCSPTQSLDLRNSKGENL 1256
                  468899999999999999999999999999999999999998888665 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0     0.099   2.5e+02       5      22 ..     949     963 ..     947     973 .. 0.79
   2 ?    0.8   0.1      0.31   7.9e+02       2      31 ..    1043    1078 ..    1042    1079 .. 0.62
   3 !   17.7   0.0   1.4e-06    0.0036       1      31 [.    1080    1111 ..    1080    1113 .. 0.75
   4 ?    5.5   0.0      0.01        26       2      27 ..    1116    1142 ..    1115    1145 .. 0.83
   5 !    7.8   0.0    0.0018       4.7       1      32 []    1182    1218 ..    1182    1218 .. 0.89
   6 ?   -0.6   0.1      0.87   2.2e+03       2      22 ..    1220    1240 ..    1219    1284 .. 0.50

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.099
                 HHHHHHHHTTHHHHHHHH CS
         Ank   5 PLHlAatngkkriiklLL 22 
                 PL +A++++   +++lLL
  EEA21954.1 949 PLLYASSEA---VVELLL 963
                 999***999...*****9 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.31
                  SBBHHHHHH..HHTTHHHHHHH..HTT..TSTTCBT CS
         Ank    2 GnTPLHlAa..tngkkriiklL..LhG..Anlnald 31  
                  G TP  lAa  +++++  +     Lh   An+n  d
  EEA21954.1 1043 GQTPFSLAAqgRINHAGRLAIMnsLHEahANPNTPD 1078
                  89******9886666434443344442237888666 PP

  == domain 3  score: 17.7 bits;  conditional E-value: 1.4e-06
                  TSBBHHHHHH.HHTTHHHHHHHH..TTTSTTCBT CS
         Ank    1 dGnTPLHlAa.tngkkriiklLL..hGAnlnald 31  
                  +G+TPLH+A+ t+ ++++i++L+  h  ++n+ +
  EEA21954.1 1080 YGRTPLHYAVlTPFNEEVIQFLVsiH--DVNLEN 1111
                  69********9555567*****9544..566554 PP

  == domain 4  score: 5.5 bits;  conditional E-value: 0.01
                  SBBHHHHHH...HHTTHHHHHHHH.TTTST CS
         Ank    2 GnTPLHlAa...tngkkriiklLL.hGAnl 27  
                  G T+L  A+   + g    i+ LL  GA++
  EEA21954.1 1116 GLTALASAVlenRKG---YIQILLaAGADP 1142
                  89******9555555...******88**98 PP

  == domain 5  score: 7.8 bits;  conditional E-value: 0.0018
                  TSBBHHHHHHHHTT...HHHHHHHH.TT.TSTTCBTT CS
         Ank    1 dGnTPLHlAatngk...kriiklLL.hG.Anlnaldn 32  
                  +G+T+L ++at g+   + + ++LL +   ++n++dn
  EEA21954.1 1182 YGRTALSWCATVGDevaAKMMSMLLeSEtVDPNLRDN 1218
                  69******99999999999******75469*****98 PP

  == domain 6  score: -0.6 bits;  conditional E-value: 0.87
                  SBBHHHHHHHHTTHHHHHHHH CS
         Ank    2 GnTPLHlAatngkkriiklLL 22  
                  G+T+L +A++ +++ +++ L 
  EEA21954.1 1220 GRTALERAICAAQPTMVSILC 1240
                  677777765444444444443 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0       3.1     8e+03      13      29 ..     953     969 ..     950     970 .. 0.71
   2 ?   -1.2   0.0       1.9   4.9e+03       2      30 ..    1009    1037 ..    1009    1038 .. 0.87
   3 ?   -2.3   0.0       4.5   1.1e+04       2      10 ..    1043    1051 ..    1042    1053 .. 0.90
   4 !   14.1   0.0   2.1e-05     0.053       1      29 [.    1080    1109 ..    1080    1110 .. 0.90
   5 ?    3.6   0.0     0.054   1.4e+02       2      29 ..    1116    1142 ..    1115    1143 .. 0.94
   6 ?    5.3   0.0     0.015        39       1      30 [.    1182    1214 ..    1182    1215 .. 0.89
   7 ?    3.4   0.0     0.063   1.6e+02       1      23 [.    1219    1241 ..    1219    1248 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 3.1
       Ank_3  13 gnle.ivkfLlenkgadv 29 
                 ++ e +v++Lle +  d+
  EEA21954.1 953 ASSEaVVELLLE-FAQDL 969
                 5555589****9.77776 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 1.9
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                  G++ L +Aa+ g   ++++ +++   dvn
  EEA21954.1 1009 GQSFLAYAAERGFERLARAAFQKVDYDVN 1037
                  788999*******9999999998888887 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 4.5
       Ank_3    2 GetpLhlAa 10  
                  G+tp+ lAa
  EEA21954.1 1043 GQTPFSLAA 1051
                  9******98 PP

  == domain 4  score: 14.1 bits;  conditional E-value: 2.1e-05
       Ank_3    1 nGetpLhlAarsgnle.ivkfLlenkgadv 29  
                  +G+tpLh+A++    e +++fL+ ++ +++
  EEA21954.1 1080 YGRTPLHYAVLTPFNEeVIQFLVSIHDVNL 1109
                  79*************87*******887775 PP

  == domain 5  score: 3.6 bits;  conditional E-value: 0.054
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadv 29  
                  G t+L  A++ ++  +++ Ll   gad+
  EEA21954.1 1116 GLTALASAVLENRKGYIQILLA-AGADP 1142
                  89********************.8*997 PP

  == domain 6  score: 5.3 bits;  conditional E-value: 0.015
       Ank_3    1 nGetpLhlAarsgnl...eivkfLlenkgadvn 30  
                  +G+t+L ++a  g+    +++ +Lle   +d+n
  EEA21954.1 1182 YGRTALSWCATVGDEvaaKMMSMLLESETVDPN 1214
                  79*************87559******8899988 PP

  == domain 7  score: 3.4 bits;  conditional E-value: 0.063
       Ank_3    1 nGetpLhlAarsgnleivkfLle 23  
                  +G+t+L +A+ ++ +++v  L+ 
  EEA21954.1 1219 EGRTALERAICAAQPTMVSILCS 1241
                  69***************999976 PP

>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.9   0.0     7e-12   1.8e-08       3     227 ..      17     330 ..      16     337 .. 0.77

  Alignments for each domain:
  == domain 1  score: 33.9 bits;  conditional E-value: 7e-12
                 EEEESSHHHHHHHHHH...EEEEEEEEEE..TTEEEEEEEETTEEEEEEE--.SSHHHHHHHHHHHHHHHC.--SEEEEEEEEEES.....STTT-TT- CS
   PNP_UDP_1   3 aiivgspgevellaes...pleetpfgre.grgfkfvtGtlkgkpvvivstG.iGkpnaavvaeirllkef.gvkaiiriGtaGgl.....npdlkvGD 90 
                 aii++ p e++++ +    +++   +g++ g    +++G+++ + vv+++   +Gk naa   +  l  +f +v   + +G++G++     + ++ +GD
  EEA21954.1  17 AIICALPLEFDAVEALfdeTYDVAAYGKQpGDANWYRIGRIGSHCVVLTCLPeMGKKNAA-SVASNLQVSFpRVNLALLVGICGAVpspseRTEVILGD 114
                 79*****999999999777777777777799999*******888888888779*******.66666666776899***********9776556677*** PP

                 EEEEEEEEESSSCCGCCTHHCC............................................................................. CS
   PNP_UDP_1  91 vvipddainfdgrsplygpkee............................................................................. 112
                 v+++d+++ +d++ ++  + +                                                                              
  EEA21954.1 115 VIVSDKIVEYDFGKQYPDVFRSnrvvketlggpnrtirsflsglktskmhdqlqndlwkyqrtleghhsgkwqypgtsqdqlfealyrhkyyhqhpdtt 213
                 *********99998865554447999999******************************************9999999999998666666654444444 PP

                 ..TCCCCTTSSEE--HHHHHHHHH................CHHTTT.................TTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESS CS
   PNP_UDP_1 113 ..gqyfpdsydapadpelrallke................aaealg.................ikvhrGvvatadgfyaeteaelrllrrlgadaveME 176
                   +                 ++++                ++   g                 + vh G  a+ad++  + +++++l ++  +   eME
  EEA21954.1 214 clC-----------------AVCHcssdpvcekapeldcrKL---GcmgslgprsrlmadppkPHVHFGSMASADTVMKSGKHRDELAATEKVIGFEME 292
                 442.................2222333433334443322234...25558889999999999999999******************************* PP

                 HHHHHHHHHHTT--EEEEEEEEETTTBETTCTCH.HCCCHHHHHHHHHHHH CS
   PNP_UDP_1 177 taavaqlArelgipfaairvvsdlaaggadaeatheeveefaqeaaknaaa 227
                 +a +  +     +p++++++v d+a+           ++  ++ aa +aa 
  EEA21954.1 293 GAGIWDI-----LPCVIMKGVCDYADS--------HKNKTWQNYAAATAAS 330
                 **99877.....788888888885555........3333333333333334 PP

>> KAP_NTPase  KAP family P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.2   0.0   1.6e-05      0.04     156     198 ..     464     507 ..     365     522 .. 0.82
   2 ?   -1.3   0.0       0.4     1e+03     182     202 ..    1298    1318 ..    1298    1323 .. 0.93

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.6e-05
  KAP_NTPase 156 eveelladmektLda..lqkrlVvviDdLDrceteevlqlleavk 198
                 e e +l+++++   +  +++r+V ++D+LD c  + v+ ++ + +
  EEA21954.1 464 EPE-MLKEIFSLVVDrlQNRRVVCFVDALDECPEDDVRDMISLFE 507
                 445.788888888888999*******************9988765 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.4
  KAP_NTPase  182 LDrceteevlqlleavkllfs 202 
                  LDrce+  ++++ +++k++++
  EEA21954.1 1298 LDRCESYGLKEISQMIKTFLE 1318
                  9*****************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1332 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       613  (0.0341904); expected 358.6 (0.02)
Passed bias filter:                      533  (0.0297284); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.90u 0.30s 00:00:01.20 Elapsed: 00:00:00.47
# Mc/sec: 8552.68
//
Query:       EEA21955.1  [L=318]
Description: 15-hydroxyprostaglandin dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.1e-42  144.8   0.0    2.9e-42  144.3   0.0    1.1  1  adh_short      short chain dehydrogenase
      4e-33  114.9   0.0    6.3e-33  114.3   0.0    1.3  1  adh_short_C2   Enoyl-(Acyl carrier protein) reductase
    8.6e-06   25.8   0.0    0.00038   20.4   0.0    2.1  2  KR             KR domain
  ------ inclusion threshold ------
       0.17   11.4   0.0       0.27   10.8   0.0    1.2  1  PP_kinase_C_1  Polyphosphate kinase C-terminal domain 1


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  144.3   0.0   6.5e-46   2.9e-42       2     191 ..      19     221 ..      18     223 .. 0.91

  Alignments for each domain:
  == domain 1  score: 144.3 bits;  conditional E-value: 6.5e-46
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT..TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---S..S--SSGGGC CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee..gakalaiqvDvtdreevealvekavkklgkldvLvnNAGi..tgsgpfsel 96 
                 vv+ tG+++G+G+ ++++l ++Gak+++ d  +  + ++a+ l++   +++++++++D +++++  +l+++a k + ++d++++NAGi  +++  + e+
  EEA21955.1  19 VVVLTGGAQGVGQSVVEKLHSAGAKIIFGDVDDTLATKLASTLNSSdgSERVHFVHCDTSNYANQLNLFQTAYKLYNRIDIVIANAGIaiHKDPFIPEH 117
                 79*******************************************999999*************************************76444444444 PP

                 SHHH.HHHH.....HHHHTHHHHHHHHHHHHHHH...HCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHH CS
   adh_short  97 seee.werv.....ievNltgvflltravlpaml...kqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdm 186
                 +++e + +      ++vNl+g++ ++r+ l ++    ++s+G+Iv vsS+ag+++ +g++ Y+AsK++v+gl+r la + +++gir+n+v+P +++T m
  EEA21955.1 118 ESDEsILSPpnlaeVDVNLKGPLYTSRLGLHYLRknnSASKGDIVLVSSIAGFKECEGLTTYTASKHGVIGLMRGLALQGEKEGIRINTVCPWMTKTRM 216
                 44443333367777******************99888899*********************************************************** PP

                 HHHHC CS
   adh_short 187 akelr 191
                 ++ ++
  EEA21955.1 217 VTGIE 221
                 98765 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.3   0.0   1.4e-36   6.3e-33       1     212 [.      24     242 ..      24     252 .. 0.83

  Alignments for each domain:
  == domain 1  score: 114.3 bits;  conditional E-value: 1.4e-36
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGH.HHHHHHHHHHTTSE.E..EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH..- CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneea.kkrveelaeelgae.v..lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpflet..s 91 
                   G a+g+G+ ++++l+++Ga++++ d+++ +  k + +l ++ g+e v  ++cD ++ ++  +l++++ + ++++Di++ nagia + k pf+    s
    EEA21955.1  24 GGAQGVGQSVVEKLHSAGAKIIFGDVDDTLaTKLASTLNSSDGSErVhfVHCDTSNYANQLNLFQTAYKLYNRIDIVIANAGIAIH-KDPFIPEheS 119
                   6689**************************7777777777777666667************************************9.6666543113 PP

                   HHHH.....HHHHHHHTHHHHHHHHHHHHHCTSC.....CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTG CS
  adh_short_C2  92 reef.....draldvnlyslfllakaalplmkeg.....gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTla 178
                   +e++        +dvnl++ +++++  l++++++     g iv +ss+++ +  ++ + y+a+K+++++l+r lA +  ++giR+N+v+p ++kT++
    EEA21955.1 120 DESIlsppnLAEVDVNLKGPLYTSRLGLHYLRKNnsaskGDIVLVSSIAGFKECEGLTTYTASKHGVIGLMRGLALQGEKEGIRINTVCPWMTKTRM 216
                   3333111113568****************777766999999******************************************************** PP

                   GGGSTTHHHHHHHHHHHSTTSS-B-HHHHHHHHH CS
  adh_short_C2 179 asgikgfdelleelearaplgrlgtpeevaeaal 212
                   ++gi++      + +   p +   +pe+va+a+l
    EEA21955.1 217 VTGIEQ-----GWYNLGLPSN---EPEDVANAIL 242
                   ****83.....2222222322...4666666666 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.0   8.4e-08   0.00038       3      93 ..      20     108 ..      18     123 .. 0.83
   2 ?    3.2   0.0     0.016        74     131     160 ..     161     190 ..     143     209 .. 0.76

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 8.4e-08
                 EEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHT..T-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE------ CS
          KR   3 ylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaeleal..gaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlr 93 
                 +++tGG+ g+G+++++ l + ga+  ++++     d  +++l ++l+++    +v++v++D s+ ++  +l++++ +  ++i  vi  Ag++ 
  EEA21955.1  20 VVLTGGAQGVGQSVVEKLHSAGAK--IIFGDV--DDTLATKLASTLNSSdgSERVHFVHCDTSNYANQLNLFQTAYKLYNRIDIVIANAGIAI 108
                 689********************9..456666..44555556666766642559***********************************9864 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.016
                 EEEEEEHHHHH--TT-HHHHHHHHHHHHHH CS
          KR 131 fvlfSSiagllgsagqanYaaaNaflDala 160
                 +vl+SSiag+    g ++Y+a  + + +l+
  EEA21955.1 161 IVLVSSIAGFKECEGLTTYTASKHGVIGLM 190
                 699*****************9876655555 PP

>> PP_kinase_C_1  Polyphosphate kinase C-terminal domain 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   6.1e-05      0.27      85     135 ..      34      85 ..      31     107 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 6.1e-05
                    HHHHHHHT-EEEE--TT--B--EEEEEEE--.-S---EEEEEESS-SS---S CS
  PP_kinase_C_1  85 akkleeagvkvvygvvglkvhaklllvvrre.eeklrryvhlgtGnynekta 135
                     +kl++ag+k+++g v+    +kl+   +++ +++  ++vh  t ny ++  
     EEA21955.1  34 VEKLHSAGAKIIFGDVDDTLATKLASTLNSSdGSERVHFVHCDTSNYANQLN 85 
                    689*********************98776661567799*********98755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (318 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       436  (0.0243181); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2218.57
//
Query:       EEA21956.1  [L=517]
Description: yapsin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.6e-63  213.9   2.4    4.7e-63  213.5   2.4    1.1  1  Asp             Eukaryotic aspartyl protease
    1.1e-10   42.1   0.5    1.7e-06   28.4   0.1    2.6  2  TAXi_N          Xylanase inhibitor N-terminal
    6.1e-07   29.4   0.0    2.4e-06   27.4   0.0    2.0  2  TAXi_C          Xylanase inhibitor C-terminal
     0.0052   17.4   0.8        4.2    8.1   0.0    3.6  3  Asp_protease_2  Aspartyl protease


Domain annotation for each model (and alignments):
>> Asp  Eukaryotic aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  213.5   2.4   1.1e-66   4.7e-63       2     314 ..      54     393 ..      53     394 .. 0.84

  Alignments for each domain:
  == domain 1  score: 213.5 bits;  conditional E-value: 1.1e-66
                 EEEEEEETTTTEEEEEEEETT--SEEEEBTT.EST.SHCHHTSS-B-GGG-TT-E..EEEEEEEEECTTS..EEEEEEEEEEEEETTEEEEEEEEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxx.xxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp   2 YfgeisiGtpeqkftvifDTGSsdlWVpssk.ckk.ssackshstydpskSstyk..kngkslsisYGdg..svsGflsqdtvkvggltvknqefgeat 94 
                 Yf + ++Gtp q  ++++DTGSsd+W +  + c+  +s+c    +ydpskSst++  +    + i+YG+   sv+G +  d+ +vg+ +vkn+++++at
  EEA21956.1  54 YFVNATVGTPGQLVQLVLDTGSSDVWFFGPNsCNAqTSDCL-GGIYDPSKSSTVQlfEPTGGFFIQYGTPnsSVTGNYILDNFSVGEASVKNLTMAYAT 151
                 999************************98664887677776.589**********76677889******77899************************* PP

                 EESSHHHTTSSSSEEEE-S-GGGSCGG.....SCCHHHH....HHHTTSSSSSEEEEEE-STTSSEEEEEESSEEGGGEEEEEEEEEESS........T CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........x RF
         Asp  95 kepgstflaakfdGiLGlgfkeisvee.....atpvfdn....lvsqglikepvfsvylnreeeeggeivfGgvDeskykGsltyvpvts........k 176
                 +++          Gi+G+gf+++++           + n    l+sq++i++ ++s++ln  ++++g+ +fGg+D++k++G+l +vp++         +
  EEA21956.1 152 NAQYV------PTGIMGIGFDTNEAITgeggqP---YPNfvdiLKSQNVISTRAYSLWLNDLDSKTGNCLFGGYDTKKFSGNLLTVPIQPdessrqltS 241
                 *9984......78**********9987665432...4444445*********************************************98777765442 PP

                 SSTEEEEEEEEETTEEE.....EEEEEEEEEEETTCSSEEEEHHHHHHHHHHHTTEEEETTCEEEEETTGGGGSEEEEEEE...TTEEEEEEGGGGEEE CS
                 xxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxx RF
         Asp 177 gywqielesvtvggktv.....lcssgcqailDtGTsllalptsivekiakaigakksesegeyvvdCdslsslpdisfti...ggakitvpvselvlk 267
                    ++  +s+ +++k+      + s ++ a+lD+GT++ ++p +i + + k + a+ +e  g  +v+C+ l +  ++ ft+   +g +i+vp s++ l 
  EEA21956.1 242 --MTVAWTSLGITTKSGsqtitAASFKSPALLDSGTTVSIVPMDIYQLLLKFFDATVDEA-GDAIVQCALLDEAGSLDFTFggpNGPTIKVPFSQFALP 337
                 ..33333333333332222446777788899***************************99.********************888899*********976 PP

                 ESSST.........TSEEEESEEECCTSSSEEEEHHHHTTEEEEEETTTTEEEEEE CS
                 xxxxx.........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp 268 eeese.........esqCilglvseeegdlwiLGdvFlrsayvvfdldnnrvglAe 314
                   +++         +  C+lgl  +++   +iLGd+Flrsayvv+dldn++++lA+
  EEA21956.1 338 AMNTNggqakfndgSLACFLGLEGTQGDMPVILGDTFLRSAYVVYDLDNKQISLAQ 393
                 54433111111111457*****88999999*************************8 PP

>> TAXi_N  Xylanase inhibitor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.4   0.1   3.8e-10   1.7e-06       1      53 [.      54     108 ..      54     114 .. 0.83
   2 !   11.5   0.1   5.8e-05      0.26      82     178 .]     116     215 ..     111     215 .. 0.82

  Alignments for each domain:
  == domain 1  score: 28.4 bits;  conditional E-value: 3.8e-10
      TAXi_N   1 YlvsisiGtppqplklvvDtGsdltWvqC.kpcka.cssqkkpvfdpsksstyka 53 
                 Y+v+  +Gtp+q ++lv+DtGs+ +W+   + c+a +s++  +++dpsksst + 
  EEA21956.1  54 YFVNATVGTPGQLVQLVLDTGSSDVWFFGpNSCNAqTSDCLGGIYDPSKSSTVQL 108
                 9*************************75403333346888899********9876 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 5.8e-05
      TAXi_N  82 eisygadgssssGvlatdtltlsstdgksvkvpnlvfGCgksnlgglaagadGilGLGrgk............lSlvsqlaskg.slgnkFsyCLssss 167
                  i+yg+ +ss++G+++ d++++     ++++v+nl+++ ++ n + ++   +Gi+G G+                +v+ l+s++ + +++ s+ L ++ 
  EEA21956.1 116 FIQYGTPNSSVTGNYILDNFSV-----GEASVKNLTMAYAT-NAQYVP---TGIMGIGFDTneaitgeggqpyPNFVDILKSQNvISTRAYSLWL-NDL 204
                 689998899*************.....899*******9998.455555...6******9887888888888888888888888766677778888.777 PP

      TAXi_N 168 ssssgvlffGd 178
                 +s++g+ +fG+
  EEA21956.1 205 DSKTGNCLFGG 215
                 88888888885 PP

>> TAXi_C  Xylanase inhibitor C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0       0.4   1.8e+03      95     125 ..      67      96 ..      46     137 .. 0.72
   2 !   27.4   0.0   5.4e-10   2.4e-06      26     158 ..     262     390 ..     238     393 .. 0.77

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.4
                 EEEEESSS-.EEEE-GGGGEEE-SSSEEEE-E CS
      TAXi_C  95 itlvlegga.ewtisgenllvkveggvvClaf 125
                 ++lvl+ g+ +++++g n+   ++ +  Cl+ 
  EEA21956.1  67 VQLVLDTGSsDVWFFGPNSCNAQTSD--CLGG 96 
                 78888887778888888888777666..6654 PP

  == domain 2  score: 27.4 bits;  conditional E-value: 5.4e-10
                 -S----SEEE-SSSSSEEE-HHHHHHHHHHHHHTS-GG...GE---TT-S-EEETTS......-S----EEEEESSS-.EEEE-GGGGEEE-SSSEEEE CS
      TAXi_C  26 dktgsggtvlstgtpytvletdvYralvkafakelaaekvkrvaavkpfelCynsselgstragpavPtitlvlegga.ewtisgenllvkveggvvCl 123
                 +++ +  ++l++gt++ +++ d+Y+ l k f++ +++ +     a  +  l  ++ +l  t  gp+ Pti++ + + a     ++     +++g+++C+
  EEA21956.1 262 AASFKSPALLDSGTTVSIVPMDIYQLLLKFFDATVDEAG-D---AIVQCALLDEAGSLDFTFGGPNGPTIKVPFSQFAlPAMNTNGGQAKFNDGSLACF 356
                 555678899****************************96.2...3333344445555556889999*********97754444444556667899**** PP

                 -EEE--S--SSSEEE-HHHHBTS-EEEETTTTEEE CS
      TAXi_C 124 afvesgvagesavviGglqlednllvFDleksrlg 158
                   +e+ ++g+ +v++G   l+  ++v+Dl++++++
  EEA21956.1 357 LGLEG-TQGDMPVILGDTFLRSAYVVYDLDNKQIS 390
                 *****.99***********************9987 PP

>> Asp_protease_2  Aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.8   0.0    0.0098        44       3      22 ..      58      79 ..      56      88 .. 0.79
   2 !    8.1   0.0   0.00095       4.2      50      89 ..     124     164 ..     102     165 .. 0.81
   3 ?    0.1   0.1      0.29   1.3e+03      12      27 ..     269     284 ..     245     298 .. 0.85

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0098
  Asp_protease_2  3 vtin..GkpvrfllDTGasttl 22
                    +t++  G+ v+++lDTG+s + 
      EEA21956.1 58 ATVGtpGQLVQLVLDTGSSDVW 79
                    555434899*********9875 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.00095
  Asp_protease_2  50 evkarlvrldslklggltlknvpalvldlge.eidglLGmd 89 
                     ++ +  + ld++++g++++kn++++++ + +  ++g++G+ 
      EEA21956.1 124 SSVTGNYILDNFSVGEASVKNLTMAYATNAQyVPTGIMGIG 164
                     34566789***************999885442678999976 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.29
  Asp_protease_2  12 fllDTGasttlispel 27 
                     +llD+G ++++++ + 
      EEA21956.1 269 ALLDSGTTVSIVPMDI 284
                     7999999999887665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (517 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       520  (0.0290033); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.26s 00:00:00.80 Elapsed: 00:00:00.41
# Mc/sec: 3763.17
//
Query:       EEA21957.1  [L=336]
Description: integral membrane protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-49  168.1  11.1    2.5e-49  167.8  11.1    1.1  1  SUR7      SUR7/PalI family
    0.00017   20.4   7.3    0.00027   19.7   7.3    1.3  1  OPT       OPT oligopeptide transporter protein
     0.0048   16.4   1.7     0.0091   15.5   1.7    1.4  1  Clc-like  Clc-like
  ------ inclusion threshold ------
       0.05   13.0   1.8      0.073   12.5   1.8    1.2  1  DUF373    Domain of unknown function (DUF373)


Domain annotation for each model (and alignments):
>> SUR7  SUR7/PalI family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  167.8  11.1   5.6e-53   2.5e-49       1     207 [.       9     256 ..       9     261 .. 0.95

  Alignments for each domain:
  == domain 1  score: 167.8 bits;  conditional E-value: 5.6e-53
        SUR7   1 frlillflslaalilllfailgsi.knstpltsiylskfdlsgldlaqi.................................gladvysfgvwgyC... 62 
                 + l+++  +++al+ l+f+ +g++ ++st+ +++y++++dls+l++a                                    ++d+y++g+wgyC   
  EEA21957.1   9 CILFPYAATVGALVSLIFVGIGCTnSKSTTQNDLYFFRADLSNLTSAGGssladqaasalgdltnlgsssleaalvqalaanTIRDFYDIGLWGYCagd 107
                 56789999****************77777777**********88888779************************************************9 PP

        SUR7  63 ..dnsdvnytkCskpkagypfdpleelnsesngkvd.....lPsnlrktlsklnnltkalfilhiialvlsfislvvgllaicvspdnsrllsflnlll 154
                   +  + ++++C+kp a + fdp+  ++ +s+++       lPsnl+k+l+++++++k++fi +i+a+ ++++ l+vgl+aic     srl+s++++l+
  EEA21957.1 108 ktSAGEYKVDYCTKPVAEFSFDPVAVWGLNSTSAASsgdniLPSNLQKALNTYKTVSKWMFIAYIVAFGATALGLIVGLFAIC-----SRLGSLVTSLI 201
                 9988999****************988888888776688899******************************************.....*********** PP

        SUR7 155 svlsflatllaalldtllfvfvrkkin..lkefgikaslglkflafaWlalaaal 207
                 s ++f++tl+a++++t++f+++ +++n  lk++g++ s+g++++ ++W+a a+al
  EEA21957.1 202 SGVAFFFTLAASATATGMFAVFLGTFNsaLKQYGMHGSMGKNIYVATWVATAFAL 256
                 *****************************************************98 PP

>> OPT  OPT oligopeptide transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   7.3   6.1e-08   0.00027     304     445 ..     124     261 ..     111     264 .. 0.84

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 6.1e-08
         OPT 304 itllivhtilkhgkdikaalksarsprteeddrhrrlmrkykdvpmwwylallvlslvigiivvealf.tqlpvwglllalllafllaivsaiiaGltg 401
                  ++++ ++++++ ++++aa++         ++  +++  +yk v++w+++a +v++ ++++ ++  lf    +++ l+++l+ ++++++  a  a  tg
  EEA21957.1 124 AEFSFDPVAVWGLNSTSAASSGD----NILPSNLQKALNTYKTVSKWMFIAYIVAFGATALGLIVGLFaICSRLGSLVTSLISGVAFFFTLAASATATG 218
                 56777777888888877777775....556677889999*****************************6666666777777778888888888888899 PP

         OPT 402 lnpvsgigkltqlifgallpgrpvanlvfgavvyaaaaqagdfm 445
                 + +++ +g +   + ++ + g++  n++++++v +a a +g+f 
  EEA21957.1 219 M-FAVFLGTFNSALKQYGMHGSMGKNIYVATWVATAFALGGTFF 261
                 9.99**********************************999886 PP

>> Clc-like  Clc-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   1.7     2e-06    0.0091      32     187 ..      89     252 ..      79     276 .. 0.65

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 2e-06
    Clc-like  32 ireiraivqsGLWldCtraekhvvksqd.vdegplhCvYkFdidallvyseklevid...edsavgelet.h.kFygWhkavlilllislllaalslls 124
                 +  ir   + GLW +C   +    ++++ + +   + v  F+ d + v+  +        ++   ++l++    + +  k ++i ++++   +al l++
  EEA21957.1  89 ANTIRDFYDIGLWGYCAGDKT---SAGEyKVDYCTKPVAEFSFDPVAVWGLNSTSAAssgDNILPSNLQKaLnTYKTVSKWMFIAYIVAFGATALGLIV 184
                 556788889999999996665...444445555777788888888777653322222333333333333212123345566788889999999****** PP

    Clc-like 125 gicasvsssea....ilftillvlaallalvadiiFfvaaervdsrfl.kgivgtYEkriGyafylal 187
                 g++a +s+  +    ++  +  +++   +++a ++F+v     +s     g+ g   k+i +a ++a 
  EEA21957.1 185 GLFAICSRLGSlvtsLISGVAFFFTLAASATATGMFAVFLGTFNSALKqYGMHGSMGKNIYVATWVAT 252
                 ********988545466667777788888999999999887777776656777777777776666554 PP

>> DUF373  Domain of unknown function (DUF373)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   1.8   1.6e-05     0.073     209     292 ..     156     238 ..     139     277 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.6e-05
      DUF373 209 klkesleegritfvtyvvallllligiisgyislesvssasvssglltlilafiygavewlalailtaslgkiideylkreekd 292
                  l+++   ++ +f++y+va+  +++g+i g+ ++ s   +s  ++l+  ++ f   a    a ++++++lg++ +++ +  ++ 
  EEA21957.1 156 ALNTYKTVSKWMFIAYIVAFGATALGLIVGLFAICSRL-GSLVTSLISGVAFFFTLAASATATGMFAVFLGTFNSALKQYGMHG 238
                 45555566789*******************99855444.577788888888888888888888888888887766555333222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (336 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       904  (0.0504211); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.51u 0.23s 00:00:00.74 Elapsed: 00:00:00.40
# Mc/sec: 2498.16
//
Query:       EEA21958.1  [L=1164]
Description: WD repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.8e-14   53.8  27.3    2.4e-05   25.0   0.2    9.7 10  WD40          WD domain, G-beta repeat
  ------ inclusion threshold ------
      0.058   13.0   0.4       0.34   10.5   0.5    2.2  3  Phage_tail_3  Phage tail tube protein, TTP


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0      0.24   2.1e+03       7      17 ..     132     142 ..     108     169 .. 0.75
   2 !   25.0   0.2   2.7e-09   2.4e-05       5      38 .]     215     261 ..     212     261 .. 0.88
   3 ?   -3.0   0.0       1.8   1.7e+04       9      16 ..     309     317 ..     306     322 .. 0.74
   4 !    7.9   0.3   0.00066       5.9       3      35 ..     363     400 ..     361     403 .. 0.79
   5 ?   -0.3   0.1      0.27   2.4e+03      13      33 ..     641     663 ..     626     667 .. 0.71
   6 ?    1.7   0.0     0.062   5.6e+02      23      36 ..     800     813 ..     786     813 .. 0.85
   7 !   13.1   0.0   1.5e-05      0.14       2      29 ..     831     859 ..     830     862 .. 0.86
   8 ?    1.0   0.0       0.1   9.1e+02      23      37 ..     963     977 ..     944     977 .. 0.79
   9 !    5.2   0.1    0.0049        44       9      35 ..    1009    1039 ..     998    1040 .. 0.76
  10 !    9.8   0.3   0.00017       1.5       8      38 .]    1060    1097 ..    1053    1097 .. 0.76

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.24
                 EESSSSEEEEE CS
        WD40   7 ltGHssvtsla 17 
                 +tGH+sv s++
  EEA21958.1 132 ITGHNSVLSIK 142
                 46888887774 PP

  == domain 2  score: 25.0 bits;  conditional E-value: 2.7e-09
                 EE.EESS.SSEEEEEEETTSSE...........EEEEETTSEEEEEE CS
        WD40   5 rt.ltGH.ssvtslafspdgaw...........lasGsdDgtvriWd 38 
                 ++ +tGH +s+ +++ s++ ++           las+sdD+tvriWd
  EEA21958.1 215 HHfFTGHdGSIFGVSISDELRLnkagkeqrvrlLASCSDDRTVRIWD 261
                 5538***888****99999999999999**99999***********9 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 1.8
                 SS.SSEEEE CS
        WD40   9 GH.ssvtsl 16 
                 GH s v+++
  EEA21958.1 309 GHsSRVWGV 317
                 895559999 PP

  == domain 4  score: 7.9 bits;  conditional E-value: 0.00066
                 EEEEEESS..SSEEEEE...EETTSSEEEEEETTSEEE CS
        WD40   3 clrtltGH..ssvtsla...fspdgawlasGsdDgtvr 35 
                 ++++l+ H  ++++sla    ++d   +++G+ Dg vr
  EEA21958.1 363 NITSLSHHagKHIWSLAlskGDDDTLSIFTGGNDGAVR 400
                 678999998888****98665555555789999*9998 PP

  == domain 5  score: -0.3 bits;  conditional E-value: 0.27
                 EEEEE..EETTSSEEEEEETTSE CS
        WD40  13 vtsla..fspdgawlasGsdDgt 33 
                 ++s++    pd  ++++G+ Dg+
  EEA21958.1 641 ISSIDddEIPDAGYVMTGGGDGH 663
                 66666666688899999977997 PP

  == domain 6  score: 1.7 bits;  conditional E-value: 0.062
                 SEEEEEETTSEEEE CS
        WD40  23 awlasGsdDgtvri 36 
                 +++asG++D  +ri
  EEA21958.1 800 RLIASGGEDTLIRI 813
                 569*********98 PP

  == domain 7  score: 13.1 bits;  conditional E-value: 1.5e-05
                 EEEEEEESS.SSEEEEEEETTSSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGs 29 
                 qclr+ ++H s+   +++s+dg++++s++
  EEA21958.1 831 QCLRIMSAHvSGLQQIKWSDDGRFVFSSG 859
                 8********88888999*******98654 PP

  == domain 8  score: 1.0 bits;  conditional E-value: 0.1
                 SEEEEEETTSEEEEE CS
        WD40  23 awlasGsdDgtvriW 37 
                  +la+G  Dg + +W
  EEA21958.1 963 VFLATGATDGYLAVW 977
                 4799**88****999 PP

  == domain 9  score: 5.2 bits;  conditional E-value: 0.0049
                  SS.SSEEEEE...EETTSSEEEEEETTSEEE CS
        WD40    9 GH.ssvtsla...fspdgawlasGsdDgtvr 35  
                   H ss+  l      p  ++l+sG+dD+++ 
  EEA21958.1 1009 VHtSSIKTLEhdeILPGYQLLVSGGDDNSLS 1039
                  46566777767788899999*******9986 PP

  == domain 10  score: 9.8 bits;  conditional E-value: 0.00017
                  ESS.SSEEEEE...EETTSSE...EEEEETTSEEEEEE CS
        WD40    8 tGH.ssvtsla...fspdgaw...lasGsdDgtvriWd 38  
                   +H s +t+++   f  d +    +as++ D+ v++W+
  EEA21958.1 1060 NAHaSAITAVKilsFYTDTTTtvdIASSGNDQRVKLWS 1097
                  489888****99665555555889898889*******5 PP

>> Phage_tail_3  Phage tail tube protein, TTP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0      0.83   7.5e+03      50      72 ..     647     669 ..     641     677 .. 0.85
   2 ?   -1.7   0.0      0.21   1.9e+03      93     126 ..    1016    1049 ..    1012    1066 .. 0.77
   3 ?   10.5   0.5   3.8e-05      0.34      40     111 ..    1065    1140 ..    1036    1149 .. 0.71

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 0.83
  Phage_tail_3  50 veipqvtevatsGGeqqfltyqf 72 
                   +eip+   v t GG+  ++ ++ 
    EEA21958.1 647 DEIPDAGYVMTGGGDGHYCAWRL 669
                   58999999999****99999975 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.21
  Phage_tail_3   93 tiaydpalpiyavlkkaddskqvvvlrlklPngd 126 
                    t+ +d  lp y++l + +d++ + v  +kl + d
    EEA21958.1 1016 TLEHDEILPGYQLLVSGGDDNSLSVTLVKLDDDD 1049
                    6788889999999999999999888877776554 PP

  == domain 3  score: 10.5 bits;  conditional E-value: 3.8e-05
  Phage_tail_3   40 tgsltkvssw.veipqvtevatsGGeqqfltyqfLeD.drekqipTi.ksavsitltiayd.palpiyavlkkadd 111 
                    + +++k++s+ ++ + + ++a sG++q    ++++ D  r++q p i  s +s ++  + d  a  +++++  a+ 
    EEA21958.1 1065 AITAVKILSFyTDTTTTVDIASSGNDQRVKLWSVVVDlARKTQEPVItISLKSDQYCPVADiAAMDVMEIADTAGT 1140
                    456677777527899999*******************889999997525666666654444033344444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1164 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       345  (0.0192426); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.70u 0.28s 00:00:00.98 Elapsed: 00:00:00.42
# Mc/sec: 8333.81
//
Query:       EEA21959.1  [L=379]
Description: high-affinity iron transporter FtrA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.2e-80  271.0   9.2    1.4e-80  270.7   9.2    1.0  1  FTR1             Iron permease FTR1 family
  ------ inclusion threshold ------
      0.025   14.6   0.7      0.025   14.6   0.7    2.7  2  Phage_holin_3_6  Putative Actinobacterial Holin-X, holin supe
        1.1    9.6   4.1         11    6.3   0.3    3.1  3  ESSS             ESSS subunit of NADH:ubiquinone oxidoreducta
        4.7    7.1   7.1        1.2    9.0   0.1    2.8  3  Wzy_C_2          Virulence factor membrane-bound polymerase, 


Domain annotation for each model (and alignments):
>> FTR1  Iron permease FTR1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  270.7   9.2   3.1e-84   1.4e-80       2     305 ..       8     319 ..       7     320 .. 0.96

  Alignments for each domain:
  == domain 1  score: 270.7 bits;  conditional E-value: 3.1e-84
        FTR1   2 faiflvvlregleaslivsvllallkq.....tqretdk.........lqvwagialavllalaigqafasitaalqkdkalieeellegvlsliavvv 86 
                 +++f++v+re+leas+i+svll++lkq           +         ++vw+g++++++++l+ig+af++++++l+ d ++ +e+l+eg++ lia ++
  EEA21959.1   8 VQVFFIVFRECLEASIILSVLLSFLKQglggpD-----QdqalykrlvRHVWYGAFAGIFICLIIGGAFVGVFYGLGHDVWTRAEKLWEGIFFLIACII 101
                 689************************665550.....3445556666******************************99******************* PP

        FTR1  87 iswmilwmrrvgkklkeeveqklakavaeiknrekaaqkgekgsekwalfilsFlivlREGlEavLfvaaivaytvkrvsalilgvvlGaliavvlgll 185
                 ++ m+++ +r  +k ke+++ k+ak++ ++++++k++++  ++ +++a+f+l+F+++lREG E v+fv +++   +  ++a++l+vv +++++++ g++
  EEA21959.1 102 VTAMGMALLR-INKSKEQWRIKIAKSLVQQSQNKKQSKLFGNWTRRYAMFLLPFVTTLREGVEGVVFVSGVSLGYP--ATAFPLPVVTAIIAGLACGYM 197
                 **********.*****************************************************************..9******************** PP

        FTR1 186 iyrglvklslqsffilegflLllvaagLfsvg..tlellekaeacngkdyiefkkskslskisllslllvaflavereg.leivlaliGwantgplg.l 280
                 +yrg++++s q f+i+++++L+l+aag fs++  +le +++++a  g d   +++++++++i +  +++v++++ e ++ +++++ ++Gw ntg++g +
  EEA21959.1 198 LYRGGNAMSIQFFLIASTCVLYLIAAGMFSKVvwDLEYYRFQQA-VGSDVADVGSGPGSYNILQ-TVWHVNCCNAETDNgWDVFNSILGWENTGTYGsI 294
                 ********************************9999999*****.*******************.*************99******************* PP

        FTR1 281 ivyaavwlvvlillgllliklgvrl 305
                 i y+++w+++++ + ++l ++++++
  EEA21959.1 295 IAYNVYWIFIMLTVAYMLWEERSGK 319
                 ******************9998875 PP

>> Phage_holin_3_6  Putative Actinobacterial Holin-X, holin superfamily III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.7   5.6e-06     0.025      31      93 ..      47     117 ..      43     135 .. 0.71
   2 ?   -0.8   3.9      0.33   1.5e+03      50      83 ..     184     226 ..     150     235 .. 0.53

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 5.6e-06
  Phage_holin_3_6  31 kragsgagllgaagvlallalllllvalalala.a.......lwlaalivaavllvlagvlalvglkklkk 93 
                      kr+++ +   + ag++ +l ++ ++v+++++l+         lw + + + a  +v a+ +al+ ++k k+
       EEA21959.1  47 KRLVRHVWYGAFAGIFICLIIGGAFVGVFYGLGhDvwtraekLWEGIFFLIACIIVTAMGMALLRINKSKE 117
                      8999************************9999432344445666665556566666666666655555554 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.33
  Phage_holin_3_6  50 alllllvala..lal...aa..lwlaali..vaavllvlagvl 83 
                       +++++++la  ++l   +   +   +li  +++++l++ag++
       EEA21959.1 184 VVTAIIAGLAcgYMLyrgGNamSIQFFLIasTCVLYLIAAGMF 226
                      3333333333332222221023344444432356666666655 PP

>> ESSS  ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   0.3    0.0024        11      39      71 ..      38      73 ..      36      87 .. 0.77
   2 ?    3.8   0.1     0.014        64      37      87 ..      75     125 ..      72     136 .. 0.69
   3 ?   -1.2   0.1      0.54   2.4e+03      62      93 ..     293     325 ..     283     327 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0024
        ESSS 39 Gfdkdpvedkenmeavf...ffgvsivlVlgsvfva 71
                G d+d++  k+ ++ v+   f g+ i+l++g++fv 
  EEA21959.1 38 GPDQDQALYKRLVRHVWygaFAGIFICLIIGGAFVG 73
                5688999999999999944457899*********85 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.014
        ESSS  37 shGfdkd.pvedkenmeavfffgvsivlVlgsvfvaYlpdtsiqeWArrEAe 87 
                 ++G  +d  +  ++ +e +ff+   i++ + +++     ++s ++W  + A+
  EEA21959.1  75 FYGLGHDvWTRAEKLWEGIFFLIACIIVTAMGMA-LLRINKSKEQWRIKIAK 125
                 8999999788899999999998666555555544.44555666666655555 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 0.54
        ESSS  62 vlVlgsvfvaYlpdt.siqeWArrEAerllkrR 93 
                 ++++  v++ +   t   + W  r ++r l+ R
  EEA21959.1 293 SIIAYNVYWIFIMLTvAYMLWEERSGKRSLRER 325
                 566677888887776247889999999999877 PP

>> Wzy_C_2  Virulence factor membrane-bound polymerase, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.1   0.00027       1.2      21     112 ..      54     145 ..      53     160 .. 0.70
   2 ?   -1.3   0.4      0.39   1.7e+03      44      61 ..     208     219 ..     175     243 .. 0.40
   3 ?    1.0   0.1     0.077   3.5e+02      22      51 ..     297     326 ..     295     340 .. 0.65

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00027
     Wzy_C_2  21 wYspfl.laaflvl.gllds......ksrsrrlrlrpklvlrvvalvlallglalllsilhdyqrleqlyltsepneaalrevtnpkvwkdrflfraya 111
                 wY++f  ++++l++ g++        ++ ++r  + +++   +++l++ ++++a+ + +l+ ++  eq +++ ++   ++++ + +k +    lf ++ 
  EEA21959.1  54 WYGAFAgIFICLIIgGAFVGvfyglgHDVWTRAEKLWEG---IFFLIACIIVTAMGMALLRINKSKEQWRIKIAKS--LVQQSQ-NKKQS--KLFGNWT 144
                 999997356677778888889997777777777777776...8888888888888888888888888888887776..333333.33233..3666655 PP

     Wzy_C_2 112 d 112
                 +
  EEA21959.1 145 R 145
                 4 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.39
     Wzy_C_2  44 rlrlrpklvlrvvalvla 61 
                 ++       l +++ vl 
  EEA21959.1 208 QFF------LIASTCVLY 219
                 222......222222222 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 0.077
     Wzy_C_2  22 Yspfllaaflvl.glldsksrsrrlrlrpkl 51 
                 Y    ++++l + ++l++ +rs + +lr + 
  EEA21959.1 297 YNVYWIFIMLTVaYMLWE-ERSGKRSLRERI 326
                 555667788888899999.444444444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (379 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       961  (0.0536003); expected 358.6 (0.02)
Passed bias filter:                      548  (0.030565); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.56u 0.31s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 2429.89
//
Query:       EEA21960.1  [L=613]
Description: ferrooxidoreductase Fet3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.6e-47  158.3   7.2      1e-41  141.9   1.0    3.1  3  Cu-oxidase_2    Multicopper oxidase
    3.5e-42  143.2   4.4    8.1e-39  132.3   0.7    3.3  3  Cu-oxidase_3    Multicopper oxidase
    1.3e-40  139.2   2.0    2.5e-35  122.0   0.1    3.0  3  Cu-oxidase      Multicopper oxidase
    0.00033   20.7   0.0          5    7.3   0.0    3.6  3  Cupredoxin_1    Cupredoxin-like domain
  ------ inclusion threshold ------
       0.04   14.5   0.2         13    6.4   0.2    2.4  2  Self-incomp_S1  Plant self-incompatibility protein S1


Domain annotation for each model (and alignments):
>> Cu-oxidase_2  Multicopper oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.5   3.7e-07    0.0013      32     121 ..      51     127 ..      30     142 .. 0.77
   2 ?   -2.4   0.0      0.98   3.5e+03      24      90 ..     187     245 ..     169     270 .. 0.61
   3 !  141.9   1.0   2.9e-45     1e-41       1     136 [.     364     509 ..     364     510 .. 0.91

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 3.7e-07
                   SEEEEEETTEEEEEEEEE-SSS.-EEEEESS-EEEEEEEEECCCCCCTCCSSGCCGSSCBSEEEE-TTEEEEEEEES.S-EEEEEEESSHH CS
  Cu-oxidase_2  32 tnvitlpkgevveiviqnntkl.pHPfHlHGhdfqvlgrgpgndpeedpksynlenpvrrdtvqvppggwvairfkadnpGvwllHCHilw 121
                    +vi+++kg+++++ + n       ++H+HG+ fq   ++             ++ p       +ppg+ +++ f++++ G + +HCH ++
    EEA21960.1  51 LPVIEVDKGDRLIVKVYNGLGDkGTSIHFHGM-FQNETNE-------------MDGPSMVTQCPIPPGSSFTYNFTVNQNGTYWYHCHTDF 127
                   57899999999999888855555689999999.4443222.............244566667889***********************986 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.98
                   ETCCTTTSSEEEEEET..TEEEEEEEEE-SSS.-EEEEESS-EEEEEEEEECCCCCCTCCSSGCCGSSCB CS
  Cu-oxidase_2  24 ngeefsentnvitlpk..gevveiviqnntkl.pHPfHlHGhdfqvlgrgpgndpeedpksynlenpvrr 90 
                   n+  f+ +++ i+lp   +++  + + n + +  + f ++ h++ +++ ++             ++p + 
    EEA21960.1 187 NSLLFNDTAHGINLPVkpNTTYLLRLINIGAFvAQYFYIEDHTMTIVEIDGVY-----------TEPAEA 245
                   66677777777777776677777777777776667777777777777665555...........344444 PP

  == domain 3  score: 141.9 bits;  conditional E-value: 2.9e-45
                   XXS-SCCCCCCCEEEEEEEEEEEETCCTTTSSEEEEEETTEEEEEEEEE-SSS-EEEEESS-EEEEEEEEECC..............CCCCTCCSSG CS
  Cu-oxidase_2   1 dvppklptllqltsgneeaseitngeefsentnvitlpkgevveiviqnntklpHPfHlHGhdfqvlgrgpgn..............dpeedpksyn 83 
                   ++ppk+ptl+++ s++++a+   n++ ++e t+ ++l+++evvei+++n++k+ HPfHlHGh+fq+l+r pg                         
    EEA21960.1 364 YTPPKVPTLYTVLSAGDQAT---NPTVYGEFTHSMVLEHNEVVEIILNNMDKGSHPFHLHGHNFQMLARYPGYgadyfeladgdpvpY--------D 449
                   68***********9999999...*************************************************9999999665555433........3 PP

                   C.......CGSSCBSEEEE-TTEEEEEEEES.S-EEEEEEESSHHHHHTT-EEEEEEECH CS
  Cu-oxidase_2  84 l.......enpvrrdtvqvppggwvairfkadnpGvwllHCHilwHldqGmalqfvvrpd 136
                           + p+rrd++ +pp+g+++irfkadnpGvw++HCHi+wHl qG+ + f++ p+
    EEA21960.1 450 AsnhsefpTYPPRRDVFVLPPHGHFVIRFKADNPGVWIFHCHIDWHLAQGLGMLFIEAPA 509
                   3444555679**********************************************9986 PP

>> Cu-oxidase_3  Multicopper oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.3   0.7   2.3e-42   8.1e-39       2     117 ..      27     142 ..      26     144 .. 0.97
   2 ?   -0.9   0.1      0.45   1.6e+03      30      57 ..     396     423 ..     380     433 .. 0.68
   3 !   10.3   0.0   0.00015      0.55      75     117 ..     468     508 ..     464     510 .. 0.89

  Alignments for each domain:
  == domain 1  score: 132.3 bits;  conditional E-value: 2.3e-42
                   EEEEEEECTTEESEEEEEECTSSBS-EEEEETT-EEEEEEEE-S.SS-B-EEEET--S-GG.....GSCSGGG-B-TT-EEEEEEE--S-SEEEEEE CS
  Cu-oxidase_3   2 vtektvsplggterevitvNgqfpgptievregdtvvvnvtNkl.dentsihwhGlqqrktswmDGvpgvtqcpiqpgesftyrftvkqqagtlwYh 97 
                   vt+  ++p+g  +r+v+ +Ngq+p p iev++gd+++v+v N l d++tsih+hG+ q++t+ mDG+++vtqcpi+pg+sfty+ftv+q +gt+wYh
    EEA21960.1  27 VTWVVANPDGLADRKVVSINGQWPLPVIEVDKGDRLIVKVYNGLgDKGTSIHFHGMFQNETNEMDGPSMVTQCPIPPGSSFTYNFTVNQ-NGTYWYH 122
                   7889999**********************************************************************************.******* PP

                   E--TTHHHTT-EEEEEEE-H CS
  Cu-oxidase_3  98 shlslqqaaGlaGaiiiedk 117
                    h+++ + +G   a+i++d+
    EEA21960.1 123 CHTDFCYPDGYRQALIVHDN 142
                   *****************997 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.45
                   EEETT-EEEEEEEE-SSS-B-EEEET-- CS
  Cu-oxidase_3  30 evregdtvvvnvtNkldentsihwhGlq 57 
                    ++ ++ v++ + N  + +   h+hG +
    EEA21960.1 396 VLEHNEVVEIILNNMDKGSHPFHLHGHN 423
                   4566666777665555555666666644 PP

  == domain 3  score: 10.3 bits;  conditional E-value: 0.00015
                   B-TT-EEEEEEE--S-SEEEEEEE--TTHHHTT-EEEEEEE-H CS
  Cu-oxidase_3  75 iqpgesftyrftvkqqagtlwYhshlslqqaaGlaGaiiiedk 117
                   ++p+ +f+ rf++++  g   +h h++++ a+Gl G++ ie++
    EEA21960.1 468 LPPHGHFVIRFKADN-PGVWIFHCHIDWHLAQGL-GMLFIEAP 508
                   799************.************977876.89999877 PP

>> Cu-oxidase  Multicopper oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   4.9e-06     0.018      41     138 ..      45     126 ..      29     146 .. 0.82
   2 !  122.0   0.1   6.9e-39   2.5e-35       2     137 ..     153     279 ..     152     301 .. 0.86
   3 ?   -0.7   0.1      0.38   1.3e+03      73      93 ..     404     425 ..     361     428 .. 0.75

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 4.9e-06
                 ETTBSS.......CTTTTSGGGEEEEETTEEEEEEEESSS-BEEEEETSB-EEEEEETCETTS.EEEESCEEE-TTEEEEEEEEE-SSSEEEEEEEEGS CS
  Cu-oxidase  41 ingkggfnatladkdgaslatltvepgktyrlriinvsaddslnfsIeGHkltVvevDgvyve.pvevdsldIavGqrysvlvtanqapgnYwivasgr 138
                 ing            +  l++++v++g++  + + n+  d+  ++ ++G      + + + ++ p  v++  I +G++++  +t nq +g+Yw+++++ 
  EEA21960.1  45 ING------------QWPLPVIEVDKGDRLIVKVYNGLGDKGTSIHFHGM----FQNETNEMDgPSMVTQCPIPPGSSFTYNFTVNQ-NGTYWYHCHTD 126
                 444............56799*****************************9....788999999************************.********522 PP

  == domain 2  score: 122.0 bits;  conditional E-value: 6.9e-39
                 EEEEEEEEETCBCTTSCBC.HSSCHCHHHHHTT--SEEEETTBSS.......CTTTTSGGGEEEEETTEEEEEEEESSS-BEEEEETSB-EEEEEETCE CS
  Cu-oxidase   2 eyvitlsDwyhkdakelekellasgkapadtppvpdavlingkggfnatladkdgaslatltvepgktyrlriinvsaddslnfsIeGHkltVvevDgv 100
                 e+ itlsDwyh+ +++l+  ++ s  +p++++p+p+++l+n             +a    l v+p+ ty+lr+in++a  +  f Ie+H++t+ve+Dgv
  EEA21960.1 153 EFSITLSDWYHEMMEDLKP-KFMSLYNPTGAEPIPNSLLFND------------TAHGINLPVKPNTTYLLRLINIGAFVAQYFYIEDHTMTIVEIDGV 238
                 6889************999.99999*****************............455789*************************************** PP

                 TTSEEEESCEEE-TTEEEEEEEEE-S.SSEEEEEEEE...G CS
  Cu-oxidase 101 yvepvevdsldIavGqrysvlvtanq.apgnYwivas...g 137
                 y+ep+e d l Ia++qrysvl+t+++ +++nY iv      
  EEA21960.1 239 YTEPAEADILYIAAAQRYSVLLTTKNtTDKNYPIVTLadsE 279
                 ************************8857*******954432 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 0.38
                 EEE.EESSS-BEEEEETSB-EE CS
  Cu-oxidase  73 rii.nvsaddslnfsIeGHklt 93 
                  ii n   + s++f ++GH+++
  EEA21960.1 404 EIIlNNMDKGSHPFHLHGHNFQ 425
                 45556666789********986 PP

>> Cupredoxin_1  Cupredoxin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.3   0.0    0.0014         5      57      94 ..      88     125 ..      26     139 .. 0.67
   2 ?    2.8   0.0     0.034   1.2e+02      67      96 ..     394     423 ..     376     428 .. 0.74
   3 !    6.1   0.0    0.0033        12      69     100 ..     467     499 ..     449     500 .. 0.84

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0014
  Cupredoxin_1  57 eefesedlgeekvlapgktttitiaplkpGeYeftcdm 94 
                    e+  +++ ++  ++pg+++t +++  + G+Y ++c  
    EEA21960.1  88 NEMDGPSMVTQCPIPPGSSFTYNFTVNQNGTYWYHCHT 125
                   45555557777889**********************84 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.034
  Cupredoxin_1  67 ekvlapgktttitiaplkpGeYeftcdmhm 96 
                   + vl+ ++  +i +++ ++G+++f+   h+
    EEA21960.1 394 SMVLEHNEVVEIILNNMDKGSHPFHLHGHN 423
                   567778888888888888888888776554 PP

  == domain 3  score: 6.1 bits;  conditional E-value: 0.0033
  Cupredoxin_1  69 vlapgktttitiaplkpGeYeftcdmhmd.akG 100
                   vl+p+  ++i +++++pG + f+c ++   a+G
    EEA21960.1 467 VLPPHGHFVIRFKADNPGVWIFHCHIDWHlAQG 499
                   799999******************987665665 PP

>> Self-incomp_S1  Plant self-incompatibility protein S1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.2    0.0036        13      30      66 ..     101     140 ..      64     174 .. 0.70
   2 ?    5.6   0.0    0.0065        23      29      58 ..     467     496 ..     463     514 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0036
  Self-incomp_S1  30 lkpgeefsfsfkenffgttlffCefrw...gkkessfdvf 66 
                     ++pg++f+++f++n  gt  ++C+      +++++ + v 
      EEA21960.1 101 IPPGSSFTYNFTVNQNGTYWYHCHTDFcypDGYRQALIVH 140
                     6789**********99999****97765433333344333 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0065
  Self-incomp_S1  29 tlkpgeefsfsfkenffgttlffCefrwgk 58 
                     +l+p+ +f ++fk ++ g  +f+C++ w+ 
      EEA21960.1 467 VLPPHGHFVIRFKADNPGVWIFHCHIDWHL 496
                     578999**********************65 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (613 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       506  (0.0282224); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.60u 0.23s 00:00:00.83 Elapsed: 00:00:00.42
# Mc/sec: 4417.02
//
Query:       EEA21961.1  [L=425]
Description: peptidase (PNG1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.7e-14   53.1   3.2    5.6e-14   52.1   3.2    1.5  1  Rad4            Rad4 transglutaminase-like domain
    5.3e-10   39.7   3.2    5.6e-10   39.7   1.8    1.8  2  Transglut_core  Transglutaminase-like superfamily


Domain annotation for each model (and alignments):
>> Rad4  Rad4 transglutaminase-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.1   3.2   6.3e-18   5.6e-14      36     147 .]     254     364 ..     251     364 .. 0.79

  Alignments for each domain:
  == domain 1  score: 52.1 bits;  conditional E-value: 6.3e-18
                 -SEEEEEEETTTTEEEEEESSSS-EESS--TTS--..TGGGS----EEEEE-TTS-EEE-HHHH-T.TCCCCHGGGSGGGSHHHHHHHHHHHHHH--S- CS
        Rad4  36 pvyWvEvfspekkkwisvdplvgstiekkeilepl..aekakqvlsYVvAfdsdgsakDVTrRYlsdysnsktkklrvekskeekkWfesvlrplekrn 132
                  ++W+Ev+s+++++w++vd++ g       +++p+   e  +  lsY +Af s  +a DVTrRY++  s++   + rv+  ++   W    +r+l++++
  EEA21961.1 254 DYVWTEVYSEHQRRWVHVDACEG------VWDQPRlyTEGWNRKLSYCIAF-SIDGATDVTRRYVRSSSKHGSPRTRVT--EDILLWAIYEIRKLRREK 343
                 589******************87......789999989999999*******.8889**********8899999999999..455555533344444444 PP

                 --H........HHHHHHHHHH CS
        Rad4 133 kert......evdalEdaelr 147
                  +++      + d++E++elr
  EEA21961.1 344 LTEQdhrrlrKEDEREERELR 364
                 433344457788999999985 PP

>> Transglut_core  Transglutaminase-like superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.7   1.8   6.2e-14   5.6e-10      21     112 .]     197     273 ..     177     273 .. 0.82
   2 ?   -3.7   0.0       1.8   1.7e+04      12      32 ..     392     412 ..     387     422 .. 0.55

  Alignments for each domain:
  == domain 1  score: 39.7 bits;  conditional E-value: 6.2e-14
  Transglut_core  21 iyewvrknveysaprrtpgsrdaeavletgkGncedfaslfvallRalGipaRvvtgylsgeeekeqsvasedaHawvevyl.egygWvplDp 112
                     ++ + ++ ++    +r p++ d++++l+t+ G+  ++a++f++l+RalG   R+v +  +              ++w+evy  ++++Wv++D+
      EEA21961.1 197 VEGYKCSGCGAL--ERFPRYSDVWQLLQTRCGRGGEWANCFTMLCRALGSRVRWVWNSED--------------YVWTEVYSeHQRRWVHVDA 273
                     444444444444..899**************************************88766..............8*******77888*****7 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 1.8
  Transglut_core  12 kdplekakaiyewvrknveys 32 
                     k+pl++ +  ++w++++ + +
      EEA21961.1 392 KTPLTQDEDAAQWINGRPQNE 412
                     455555555556655555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (425 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       877  (0.0489152); expected 358.6 (0.02)
Passed bias filter:                      551  (0.0307323); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.41
# Mc/sec: 3137.25
//
Query:       EEA21962.1  [L=480]
Description: alpha,alpha-trehalose-phosphate synthase subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   7.1e-195  648.2   0.0   8.1e-195  648.0   0.0    1.0  1  Glyco_transf_20  Glycosyltransferase family 20
  ------ inclusion threshold ------
      0.017   14.8   0.0      0.032   13.9   0.0    1.5  1  Glyco_transf_5   Starch synthase catalytic domain
        0.2   11.2   0.4         18    4.8   0.1    2.6  2  Glycos_transf_1  Glycosyl transferases group 1


Domain annotation for each model (and alignments):
>> Glyco_transf_20  Glycosyltransferase family 20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  648.0   0.0  1.4e-198  8.1e-195       2     473 ..      11     474 ..      10     475 .. 0.98

  Alignments for each domain:
  == domain 1  score: 648.0 bits;  conditional E-value: 1.4e-198
                      -EEEEEEE-SECEEE-S.SCG..EEECCGSSHHHHHCCCHHCCC-EEEEEEECCES-CCC..HCCCCHHHCCCCCEEEEEE-HHHHHHHCCCHH CS
  Glyco_transf_20   2 klvvvsnrlplklereseeekeeyelkkssgglvsalkglkeetevvwvgwlgvevdeseeakekvskeleekfsvvpvflsdekveeyyngfs 95 
                      +l+ vsnrlpl+++r++  +k  ye+++ssgglv+ l+gl+++t+++w+gw+g+ev+e+e   e+v+ +l+e++ ++pvf++d+ ++++yngfs
       EEA21962.1  11 RLLLVSNRLPLTIRRSE-GGK--YEFSMSSGGLVTGLSGLAKTTTFQWYGWPGLEVPEDE--VETVKSRLKEEYGATPVFIDDQLADRHYNGFS 99 
                      6789*********9997.777..9************************************..99****************************** PP

                      HHCHHHHHTT-GG....G----HHHHHHHHHHHHHHHHHHHCC--TT-EEEEESGGGTTHHHHHHHCCTT.....SEEEEEE-S----HHHHTT CS
  Glyco_transf_20  96 ksvLWpllHYklpdsseekefersawdaYvkvnklFAdkiveeikdgdliwvhDYhLmllPellRkkled.....akigfflHiPFPsseifri 184
                      +s+LWpllHY++     e  f++saw aY+++n lFA++i++e++dgdliwvhDYhLmllP+llR++l       +kigfflH+PFPssei+r+
       EEA21962.1 100 NSILWPLLHYHPG----EIVFDESAWVAYKEANALFANTIADEAQDGDLIWVHDYHLMLLPQLLRERLRAqgkknIKIGFFLHTPFPSSEIYRV 189
                      *************....**************************************************98888888******************* PP

                      STTHHHHHHHHTTSSEEEESSHHHHHHHHHHHHHHSSEEEECTTEEEEETTEEEEEEE------HHHHHHHCCSCHHHHHHHHHHHHT.TTSEE CS
  Glyco_transf_20 185 LpvreeilegllgadliGFhtedyarhFlsccsrllgleveskrggveykgrkvsvkalpigidverlesalkkesvsekvkelkerfenkkkl 278
                      Lpvr+++l+g+l +dliGFht+dyarhFls+cs++l+l++++    v++++++v v+a+pigid+e++ + lk+++v++++++l+++f++ +kl
       EEA21962.1 190 LPVRADLLKGVLYCDLIGFHTFDYARHFLSACSHILNLNTTPG--SVHFEDQSVAVGAFPIGIDPEKFLEGLKNPKVQNRIASLESKFQG-MKL 280
                      *******************************************..79*****************************************99.8** PP

                      EEEEEEC-GGG-HHHHHHHHHHHHHH-GGGTTTEEEEEEEEB-STTSHHHHHHHHHHHHHHHHHHHHH-BTTB-SEEEEES---HHHHHHHHHH CS
  Glyco_transf_20 279 ilgvDrlDyikGvkqkllaferfLeeypelrgkvvlvqiavpsredveeyqelekeveelvgrINgefgtldytPvvylersldfeeliallaa 372
                      +++vDrlDyikG++qkl+a+e fL+++pe+ gkvvlvq+avpsr+dveeyq+l++ v+elvgrINg+fgt+dy+P++++++s++feel+al+a+
       EEA21962.1 281 MVSVDRLDYIKGIPQKLHALEVFLSNHPEWVGKVVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTVDYMPIHFMHKSVNFEELLALYAV 374
                      ********************************************************************************************** PP

                      -SEEEE--SSBSS-CHHHHHHHCSTTT--EEEEETTBGGGGT-TTTSEEE-TT-HHHHHHHHHHHHC--HHHHHHHHHHHHHHHHHT-HHHHHH CS
  Glyco_transf_20 373 advllvtslRdGmnlvakeyvvcqqekkgvLiLSeFaGaaqsLkdaailvNPwdieevaeaikeaLkmseeerkkrekkllkqvskhdvqsWae 466
                      +d+++v+s+RdGmnlv++ey++ qq+++gvLiLSeFaGaaqsL+ ++++vNPw++e++a+a+++a++m++e+r+ + +kl+k++sk++++ W +
       EEA21962.1 375 SDACIVSSTRDGMNLVSFEYIASQQKRQGVLILSEFAGAAQSLN-GSLVVNPWNTEDLAKAYHQAVSMEPEQRAAKYQKLWKYISKYTSAFWGQ 467
                      ********************************************.78*********************************************** PP

                      HHHHHHH CS
  Glyco_transf_20 467 sflselk 473
                      sf+ el+
       EEA21962.1 468 SFVAELS 474
                      ****996 PP

>> Glyco_transf_5  Starch synthase catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   5.3e-06     0.032     107     170 ..     120     178 ..      56     203 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 5.3e-06
  Glyco_transf_5 107 dyednaerfalfsraalelleklgwkpdvihahDWhtalvpallkelykerglfkkiktvftiH 170
                      +   +e  alf++ +++ ++      d+i +hD+h +l+p ll+e  +  +  k+ik+ f +H
      EEA21962.1 120 AWVAYKEANALFANTIADEAQD----GDLIWVHDYHLMLLPQLLRERLR-AQGKKNIKIGFFLH 178
                     4555566667788887777777....6*******************953.45667799999999 PP

>> Glycos_transf_1  Glycosyl transferases group 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0     0.008        48      12      49 ..     275     311 ..     266     339 .. 0.86
   2 ?    4.8   0.1    0.0031        18      76     164 ..     358     447 ..     355     454 .. 0.66

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.008
                      TTT-EEEEEESS-TTTTTHHHHHHHHHCCCCCHCSCEE CS
  Glycos_transf_1  12 nekkkiilsvgrlekeKgvdllikafallkkqlnpnvk 49 
                       ++ k+++sv rl++ Kg+ + ++a++ +  + +p+++
       EEA21962.1 275 FQGMKLMVSVDRLDYIKGIPQKLHALEVFLSN-HPEWV 311
                      467899*********************99998.88875 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.0031
                      GEEECCHSSSHHHHHHCESEEEEEESSBSS-HHHHHHHHTT-....-EEEETTTTHCHHCHTTT..SEEEE-TT.-HHHHHHHHHHHHHSHHHH CS
  Glycos_transf_1  76 iflgevsredleellknadifvlpsisEgfGivllEAmaagl....pviasnaggpaevvkdge..tGllvkpn.naealaeairklledeelr 162
                      ++++ v+ e+l +l+  +d+ +++s+++g+ +v  E++a+        i s           ++  +G lv ++ n e+la+a  ++++ e+++
       EEA21962.1 358 FMHKSVNFEELLALYAVSDACIVSSTRDGMNLVSFEYIASQQkrqgVLILSE------FAGAAQslNGSLVVNPwNTEDLAKAYHQAVSMEPEQ 445
                      5667777888999999999999999999999999999887541111233333......333333346667777778888888888888887554 PP

                      HH CS
  Glycos_transf_1 163 er 164
                      ++
       EEA21962.1 446 RA 447
                      44 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (480 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       487  (0.0271627); expected 358.6 (0.02)
Passed bias filter:                      470  (0.0262145); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.46
# Mc/sec: 3158.18
//
Query:       EEA21963.1  [L=501]
Description: alpha,alpha-trehalose-phosphate synthase subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
     4e-190  632.5   0.0   4.7e-190  632.3   0.0    1.0  1  Glyco_transf_20  Glycosyltransferase family 20
  ------ inclusion threshold ------
      0.018   14.7   0.0      0.034   13.8   0.0    1.4  1  Glyco_transf_5   Starch synthase catalytic domain
       0.23   11.0   0.4         20    4.7   0.1    2.6  2  Glycos_transf_1  Glycosyl transferases group 1


Domain annotation for each model (and alignments):
>> Glyco_transf_20  Glycosyltransferase family 20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  632.3   0.0  7.9e-194  4.7e-190       2     463 ..      11     464 ..      10     474 .. 0.97

  Alignments for each domain:
  == domain 1  score: 632.3 bits;  conditional E-value: 7.9e-194
                      -EEEEEEE-SECEEE-S.SCG..EEECCGSSHHHHHCCCHHCCC-EEEEEEECCES-CCC..HCCCCHHHCCCCCEEEEEE-HHHHHHHCCCHH CS
  Glyco_transf_20   2 klvvvsnrlplklereseeekeeyelkkssgglvsalkglkeetevvwvgwlgvevdeseeakekvskeleekfsvvpvflsdekveeyyngfs 95 
                      +l+ vsnrlpl+++r++  +k  ye+++ssgglv+ l+gl+++t+++w+gw+g+ev+e+e   e+v+ +l+e++ ++pvf++d+ ++++yngfs
       EEA21963.1  11 RLLLVSNRLPLTIRRSE-GGK--YEFSMSSGGLVTGLSGLAKTTTFQWYGWPGLEVPEDE--VETVKSRLKEEYGATPVFIDDQLADRHYNGFS 99 
                      6789*********9997.777..9************************************..99****************************** PP

                      HHCHHHHHTT-GG....G----HHHHHHHHHHHHHHHHHHHCC--TT-EEEEESGGGTTHHHHHHHCCTT.....SEEEEEE-S----HHHHTT CS
  Glyco_transf_20  96 ksvLWpllHYklpdsseekefersawdaYvkvnklFAdkiveeikdgdliwvhDYhLmllPellRkkled.....akigfflHiPFPsseifri 184
                      +s+LWpllHY++     e  f++saw aY+++n lFA++i++e++dgdliwvhDYhLmllP+llR++l       +kigfflH+PFPssei+r+
       EEA21963.1 100 NSILWPLLHYHPG----EIVFDESAWVAYKEANALFANTIADEAQDGDLIWVHDYHLMLLPQLLRERLRAqgkknIKIGFFLHTPFPSSEIYRV 189
                      *************....**************************************************98888888******************* PP

                      STTHHHHHHHHTTSSEEEESSHHHHHHHHHHHHHHSSEEEECTTEEEEETTEEEEEEE------HHHHHHHCCSCHHHHHHHHHHHHT.TTSEE CS
  Glyco_transf_20 185 LpvreeilegllgadliGFhtedyarhFlsccsrllgleveskrggveykgrkvsvkalpigidverlesalkkesvsekvkelkerfenkkkl 278
                      Lpvr+++l+g+l +dliGFht+dyarhFls+cs++l+l++++    v++++++v v+a+pigid+e++ + lk+++v++++++l+++f++ +kl
       EEA21963.1 190 LPVRADLLKGVLYCDLIGFHTFDYARHFLSACSHILNLNTTPG--SVHFEDQSVAVGAFPIGIDPEKFLEGLKNPKVQNRIASLESKFQG-MKL 280
                      *******************************************..79*****************************************99.8** PP

                      EEEEEEC-GGG-HHHHHHHHHHHHHH-GGGTTTEEEEEEEEB-STTSHHHHHHHHHHHHHHHHHHHHH-BTTB-SEEEEES---HHHHHHHHHH CS
  Glyco_transf_20 279 ilgvDrlDyikGvkqkllaferfLeeypelrgkvvlvqiavpsredveeyqelekeveelvgrINgefgtldytPvvylersldfeeliallaa 372
                      +++vDrlDyikG++qkl+a+e fL+++pe+ gkvvlvq+avpsr+dveeyq+l++ v+elvgrINg+fgt+dy+P++++++s++feel+al+a+
       EEA21963.1 281 MVSVDRLDYIKGIPQKLHALEVFLSNHPEWVGKVVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTVDYMPIHFMHKSVNFEELLALYAV 374
                      ********************************************************************************************** PP

                      -SEEEE--SSBSS-CHHHHHHHCSTTT--EEEEETTBGGGGT-TTTSEEE-TT-HHHHHHHHHHHHC--HHHHHHHHHHHHHHHHHT-HHH CS
  Glyco_transf_20 373 advllvtslRdGmnlvakeyvvcqqekkgvLiLSeFaGaaqsLkdaailvNPwdieevaeaikeaLkmseeerkkrekkllkqvskhdvqs 463
                      +d+++v+s+RdGmnlv++ey++ qq+++gvLiLSeFaGaaqsL+ ++++vNPw++e++a+a+++a++m++e+r+ + +kl+k++sk++   
       EEA21963.1 375 SDACIVSSTRDGMNLVSFEYIASQQKRQGVLILSEFAGAAQSLN-GSLVVNPWNTEDLAKAYHQAVSMEPEQRAAKYQKLWKYISKYTRLV 464
                      ********************************************.78****************************************9655 PP

>> Glyco_transf_5  Starch synthase catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   5.7e-06     0.034     107     170 ..     120     178 ..      57     203 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 5.7e-06
  Glyco_transf_5 107 dyednaerfalfsraalelleklgwkpdvihahDWhtalvpallkelykerglfkkiktvftiH 170
                      +   +e  alf++ +++ ++      d+i +hD+h +l+p ll+e  +  +  k+ik+ f +H
      EEA21963.1 120 AWVAYKEANALFANTIADEAQD----GDLIWVHDYHLMLLPQLLRERLR-AQGKKNIKIGFFLH 178
                     4555566667788887777777....6*******************953.45667799999999 PP

>> Glycos_transf_1  Glycosyl transferases group 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0    0.0085        51      12      49 ..     275     311 ..     266     339 .. 0.86
   2 ?    4.7   0.1    0.0033        20      76     164 ..     358     447 ..     355     454 .. 0.66

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.0085
                      TTT-EEEEEESS-TTTTTHHHHHHHHHCCCCCHCSCEE CS
  Glycos_transf_1  12 nekkkiilsvgrlekeKgvdllikafallkkqlnpnvk 49 
                       ++ k+++sv rl++ Kg+ + ++a++ +  + +p+++
       EEA21963.1 275 FQGMKLMVSVDRLDYIKGIPQKLHALEVFLSN-HPEWV 311
                      467899*********************99998.88875 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.0033
                      GEEECCHSSSHHHHHHCESEEEEEESSBSS-HHHHHHHHTT-....-EEEETTTTHCHHCHTTT..SEEEE-TT.-HHHHHHHHHHHHHSHHHH CS
  Glycos_transf_1  76 iflgevsredleellknadifvlpsisEgfGivllEAmaagl....pviasnaggpaevvkdge..tGllvkpn.naealaeairklledeelr 162
                      ++++ v+ e+l +l+  +d+ +++s+++g+ +v  E++a+        i s           ++  +G lv ++ n e+la+a  ++++ e+++
       EEA21963.1 358 FMHKSVNFEELLALYAVSDACIVSSTRDGMNLVSFEYIASQQkrqgVLILSE------FAGAAQslNGSLVVNPwNTEDLAKAYHQAVSMEPEQ 445
                      5667777888999999999999999999999999999887541111233333......333333346667777778888888888888887554 PP

                      HH CS
  Glycos_transf_1 163 er 164
                      ++
       EEA21963.1 446 RA 447
                      44 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (501 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       524  (0.0292264); expected 358.6 (0.02)
Passed bias filter:                      517  (0.028836); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 3275.98
//
Query:       EEA21964.1  [L=891]
Description: alpha,alpha-trehalose phosphate synthase subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   4.9e-152  506.9   0.0   7.1e-152  506.4   0.0    1.2  1  Glyco_transf_20  Glycosyltransferase family 20
    3.3e-34  118.0   0.0    6.4e-34  117.1   0.0    1.3  1  Trehalose_PPase  Trehalose-phosphatase
  ------ inclusion threshold ------
       0.12   12.5   0.1        4.7    7.2   0.0    2.8  3  DUF2487          Protein of unknown function (DUF2487)
       0.15   11.1   0.0        0.3   10.1   0.0    1.4  1  MBA1             MBA1-like protein


Domain annotation for each model (and alignments):
>> Glyco_transf_20  Glycosyltransferase family 20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  506.4   0.0  1.6e-155  7.1e-152      28     473 ..     156     605 ..     137     606 .. 0.96

  Alignments for each domain:
  == domain 1  score: 506.4 bits;  conditional E-value: 1.6e-155
                      CCGSSHHHHHCCCHHCC...C-EEEEEEECCES-CCC...HCCCCHHHCCCCCEEEEEE-HHHHHHHCCCHHHHCHHHHHTT-GG....G---- CS
  Glyco_transf_20  28 kkssgglvsalkglkee...tevvwvgwlgvevdesee.akekvskeleekfsvvpvflsdekveeyyngfsksvLWpllHYklpdsseekefe 117
                       + +ggl +a+++++++   ++ +wvg+lg+++d+ ee +++++  +l+e+f++++vf+ d ++e +y +f+ +vL+p +HY++++s+ +ke+e
       EEA21964.1 156 VQGNGGLRNAIDAAARAgivKDKAWVGTLGMPTDSLEEhTRNNIALQLKEEFDSLVVFVGDSEFEGHYFHFCRNVLYPAFHYQMQESPRHKEYE 249
                      344555666666666668877889************99999***************************************************** PP

                      HHHHHHHHHHHHHHHHHHHCC--TT-EEEEESGGGTTHHHHHHHCCTTSEEEEEE-S----HHHHTTSTTHHHHHHHHTTSSEEEESSHHHHHH CS
  Glyco_transf_20 118 rsawdaYvkvnklFAdkiveeikdgdliwvhDYhLmllPellRkkledakigfflHiPFPsseifriLpvreeilegllgadliGFhtedyarh 211
                      +++w++Yvk+n++FA++i+++ k+gd iwvhDYhLmllP++lR+kl+ a+igff+H+ FPsseifr+L+ r+++leg+lga++iG++t +y+ h
       EEA21964.1 250 DHSWKQYVKLNEMFAETIAAQWKPGDRIWVHDYHLMLLPRMLRDKLPGAEIGFFMHTAFPSSEIFRCLSARKTLLEGMLGANIIGLQTAEYVYH 343
                      ********************************************************************************************** PP

                      HHHHHHHHSSEEEECTTEEEEETTEEEEEEE------HHHHHHHCCSCHHHHHHHHHHHHT.TTSEEEEEEEEC-GGG-HHHHHHHHHHHHHH- CS
  Glyco_transf_20 212 FlsccsrllgleveskrggveykgrkvsvkalpigidverlesalkkesvsekvkelkerfenkkklilgvDrlDyikGvkqkllaferfLeey 305
                      Fl++csr+l+lev+ +  gv + +r   vka+p gid + ++++ + ++v+e+v ++ er+++k +li+g+DrlD + Gvkqkll++e+fL++y
       EEA21964.1 344 FLHTCSRILRLEVSAD--GVYLPDRLLPVKAFPMGIDLDLMNHQRQLPEVKEWVSKISERYQGK-HLIVGRDRLDAAGGVKQKLLSYEKFLKRY 434
                      ****************..8******************************************996.***************************** PP

                      GGGTTTEEEEEEEEB-STTSHHHHHHHHHHHHHHHHHHHHH-BTTB-SEEEEES---HHHHHHHHHH-SEEEE--SSBSS-CHHHHHHHCSTT. CS
  Glyco_transf_20 306 pelrgkvvlvqiavpsredveeyqelekeveelvgrINgefgtldytPvvylersldfeeliallaaadvllvtslRdGmnlvakeyvvcqqe. 398
                      pe+r++vvlvq+a++s+ d     +le ++ +++ rIN++++tl+++P+v+l++++ f++++al+++a+++++tslR+Gmnl  +++vvcq++ 
       EEA21964.1 435 PEWRDNVVLVQVASSSALDLT---DLETQITKIAMRINSKYSTLTHQPLVLLKQDITFAQFLALMSVAEIFIITSLREGMNLSGHDFVVCQDGt 525
                      *******************99...7********************************************************************* PP

                      .....T--EEEEETTBGGGGT-TTTSEEE-TT-HHHHHHHHHHHHC--HHHHHHHHHHHHHHHHHT-HHHHHHHHHHHHH CS
  Glyco_transf_20 399 .....kkgvLiLSeFaGaaqsLkdaailvNPwdieevaeaikeaLkmseeerkkrekkllkqvskhdvqsWaesflselk 473
                           ++g+LiLSeF+G+a++ +   +lvNPwd+ ++a++i++aL ms e ++k+++ l ++  kh+++ W+ ++l++l+
       EEA21964.1 526 sggpqRYGSLILSEFTGSASIWSGYELLVNPWDYVQCADTINRALCMSAEDKEKNWHFLASRMAKHTASMWCDTYLKSLR 605
                      ****************************************************************************9986 PP

>> Trehalose_PPase  Trehalose-phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.1   0.0   1.4e-37   6.4e-34      21     227 ..     661     873 ..     644     879 .. 0.86

  Alignments for each domain:
  == domain 1  score: 117.1 bits;  conditional E-value: 1.4e-37
                      -TTHHHHHHHHHTTS-..EEEE-SS-HHH.HHHHH---SSEEEEGGGTEEE-TT--EEE-.HHHHTTHHHHHHHHHHHHHHHTTSTT-EEEEET CS
  Trehalose_PPase  21 ssellslLkkLasdpknvvaivSGrslke.eellvkvpelglaaeHGaeirspsgedwen.qaevedlewlkevkeileektertpGsyiEekk 112
                       +e+ls++ +L+sdpkn++++ S r  ++ e  l++ p +gl+ae+Ga++r p++++w++   e+ + +w++ +++++e++ ert+G++iEe+ 
       EEA21964.1 661 NQEVLSMIAALSSDPKNTLYVTSSRTPQQlELSLADSPHIGLIAENGAFLREPGQSKWQQlLDETNTRDWRRGIQKVMEYFQERTEGATIEERH 754
                      57999************************9*****************************9566777889************************* PP

                      TEEEEE-TT--TT.....THHHHHHHHHHHHHHH.--EEEE-SSEEEEE-S---HHHHHHHHHHTS---..-----EEEEEE-SSTTHHHHTTS CS
  Trehalose_PPase 113 falsvHyrnadde...elqakelaehlesvltdkpdlevtqgkkvvevrpqgvsKGkaverlleslgsa..dseddfvlciGDdrtDedmFsvl 201
                      f+++++y+ a d+     qa el ++ +s  + ++++++      v v p+ v+K  ++e  l+++ s+    ++df + +G+ r+De  F++ 
       EEA21964.1 755 FSITFNYKAAVDKelaIRQAAELNDQINS-ARGNVPIRAVLTDGAVTVEPTNVTKATTAELALQRISSQpnHATPDFLFIAGNSRSDEALFKWA 847
                      *************5533344444444444.56678********************9988888887777776679******************** PP

                      -TT...-EEEEE--TTS---EES-SE CS
  Trehalose_PPase 202 rktkesgvsievsavevgskpskaky 227
                      ++ +++g   +v +v+ g+++ +a  
       EEA21964.1 848 NRIEREGRFQNVISVTMGTQAITAAA 873
                      ****6666666667767777666654 PP

>> DUF2487  Protein of unknown function (DUF2487)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   0.0    0.0011       4.7      31     111 ..     203     288 ..     174     298 .. 0.65
   2 ?   -3.2   0.0       1.8   8.1e+03      92     125 ..     597     634 ..     577     640 .. 0.67
   3 ?    1.6   0.0     0.056   2.5e+02      54      95 ..     827     867 ..     825     886 .. 0.81

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0011
     DUF2487  31 sqaefiallaeelErqlkG......RvlllPaftYlkeeekeeeverlkeweeelkeegfkhvvfitsdeewkelee..elegkliwvp 111
                  + ef +l++   + +++G      R +l Paf Y ++e+ +++  + ++w++ +k +    ++  t  ++wk  ++    + +l+++p
  EEA21964.1 203 LKEEFDSLVVFVGDSEFEGhyfhfcRNVLYPAFHYQMQESPRHKEYEDHSWKQYVKLN---EMFAETIAAQWKPGDRiwVHDYHLMLLP 288
                 45555556655556666664444558899**********9999988999****99876...5677777778877766533333666666 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 1.8
     DUF2487  92 sdeewkelee....elegkliwvpaiplesldesqkqk 125
                 +d+  k+l++    + + +l  +++++++++ e+++q+
  EEA21964.1 597 CDTYLKSLRQayeiQASRELHTISSLSMDTVREKYNQS 634
                 55555554444423445688888888888888888775 PP

  == domain 3  score: 1.6 bits;  conditional E-value: 0.056
     DUF2487  54 lPaftYlkeeekeeeverlkeweeelkeeg.fkhvvfitsdee 95 
                 +P f ++  +++++e   l +w++++++eg f++v+ +t+ ++
  EEA21964.1 827 TPDFLFIAGNSRSDE--ALFKWANRIEREGrFQNVISVTMGTQ 867
                 588889998888885..8********98866******998665 PP

>> MBA1  MBA1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   6.7e-05       0.3      58     104 ..     234     280 ..     202     285 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 6.7e-05
        MBA1  58 lfrlqtglkpsflewknkAietyvkvNkafAareleqleelvslwvk 104
                  f +q +  p+  e+ ++  ++yvk N+ fA+    q ++   +wv+
  EEA21964.1 234 AFHYQMQESPRHKEYEDHSWKQYVKLNEMFAETIAAQWKPGDRIWVH 280
                 5999*******************************999999999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (891 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       459  (0.025601); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.70u 0.31s 00:00:01.01 Elapsed: 00:00:00.47
# Mc/sec: 5718.49
//
Query:       EEA21965.1  [L=376]
Description: NADH:flavin oxidoreductase/NADH oxidase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.3e-98  329.6   0.0    2.6e-98  329.4   0.0    1.0  1  Oxidored_FMN  NADH:flavin oxidoreductase / NADH oxidase famil
  ------ inclusion threshold ------
      0.069   13.1   0.0       0.15   12.0   0.0    1.5  1  Tautomerase   Tautomerase enzyme


Domain annotation for each model (and alignments):
>> Oxidored_FMN  NADH:flavin oxidoreductase / NADH oxidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  329.4   0.0  2.9e-102   2.6e-98       2     340 ..       4     343 ..       3     345 .. 0.84

  Alignments for each domain:
  == domain 1  score: 329.4 bits;  conditional E-value: 2.9e-102
                   CCS-EEETTEEESSSEEE----S-TTTTTCS.HH.HHHHHHHHHHHHTT-SEEEEEEEESSCCC-SCTTSEE-SSGGGHHHHHHHHHHHHHTT-EEE CS
  Oxidored_FMN   2 LFkPikignmtLknRivmapmtrlraldkgnvle.dlaaeyysqraeipvtliiteaafvnpksggfdnapgiwdeeqieewrklteavhengskvv 97 
                   LF+P+k+g ++L +Ri+ ap+tr r  +    +   l++eyy+qra+ p+tl+i+ea+ ++p+ g++  apgiw+eeqi++w+++t+avhe+gs++ 
    EEA21965.1   4 LFTPLKVGRVELSHRIALAPLTRFRNDETTHAPIvPLVKEYYAQRASEPGTLLISEATLISPQAGAYTHAPGIWSEEQIAAWKQITDAVHEKGSYIY 100
                   9************************999988877789************************************************************ PP

                   EEEE--GGGS..SCSTCEC..SS.ESSSSSTTT-.S...CS..-EE--HHHHHHHHHHHHHHHHHHHH.TT-SEEEEEE-CTSHHHHHH-TTT---- CS
  Oxidored_FMN  98 vqlwhlGreakseyladqevdspsdpvaldaqeeesaeevy..kkeltkeeikqliqefveAAkraie.AgfDgVeihganGYLlnqFlspksnkrt 191
                    qlw lGr+a  +    q   ++  ++++  +  +s  + y  +++lt++ei+q+i+++++AAk+a+e AgfDgVe+h+anGYL++qF++   n+rt
    EEA21965.1 101 AQLWALGRAADPQAMRAQP--GAE-NFDIVSSSPVSLGKGYetPRALTEDEIQQYIKDYAQAAKNAVErAGFDGVEVHSANGYLIDQFVQTCVNQRT 194
                   **********866666666..444.44444444433333333389**************************************************** PP

                   STTSSSHHHHHHHHHHHHHHHHHHH-SSSEEEEEECE--STTS--HHHHHHHHHHHCHCCEEEEEEETT-SSSSSTTS-TTTTHHHCCTTHHHHHHC CS
  Oxidored_FMN 192 DeygGslenRarFllevvdaVkeavgeervgyRlSpedvvekgldfaetaqkivllkelekrlkdgkklalvhaaeprkrgagsvrteqekntefvk 288
                   D++gGs+enR rF+lev +aV eavg++r+++R+Sp++ ++++  + ++    ++      r+ +  ++++vh++epr+ g+  v+  + + + f+ 
    EEA21965.1 195 DQWGGSVENRSRFALEVTKAVIEAVGADRTAIRFSPFSEFQNMG-MPDA--DREATFSYLAREFAKLHVSFVHLVEPRVNGNTDVENVSGSLQFFLD 288
                   ****************************************9875.4444..222333333444446789**********999998887554444444 PP

                   CC.HSSEEEE-SS--SHHHHH..HHHHTTS-SEEEESTHHHH-TTHHHHHHCCTC CS
  Oxidored_FMN 289 ev.wkkplitvgriadeekaa..eivaegeadLvamgRefladpdlveklkkglp 340
                    +    p++ +g+++ ++ ++  e++ ++   ++a+gR+f+a+pdl++++kkg++
    EEA21965.1 289 AYaYASPVVLAGGYKADNAKEavEVRYKNLPVIIAFGRPFIANPDLPFRIKKGIE 343
                   431467999999999887444114455688899*******************986 PP

>> Tautomerase  Tautomerase enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   1.7e-05      0.15      10      38 ..     198     226 ..     196     228 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 1.7e-05
                  CS-HHHHHHHHHHHHHHHHHHHTS-GGG- CS
  Tautomerase  10 grsaeqKaeLaervTealvealgaprsai 38 
                  g+s e + ++a +vT+a++ea+ga+r+ai
   EEA21965.1 198 GGSVENRSRFALEVTKAVIEAVGADRTAI 226
                  56899999******************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (376 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       518  (0.0288917); expected 358.6 (0.02)
Passed bias filter:                      477  (0.0266049); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.31s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2471.54
//
Query:       EEA21966.1  [L=744]
Description: chromatin assembly factor 1 subunit B, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.9e-18   65.5  14.1    0.00044   21.0   0.1    7.0  7  WD40         WD domain, G-beta repeat
    8.3e-15   54.9   0.0    4.2e-05   23.8   0.0    5.1  5  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
     0.0002   21.3   0.3      0.023   14.6   0.0    2.8  3  eIF2A        Eukaryotic translation initiation factor eIF2A
     0.0038   17.0   0.2      0.015   15.2   0.2    2.1  1  HIRA_B       HIRA B motif
     0.0069   15.4   0.1        7.1    5.5   0.0    3.3  3  Ge1_WD40     WD40 region of Ge1, enhancer of mRNA-decapping p
  ------ inclusion threshold ------
      0.085   12.8   7.2         10    6.2   0.6    4.5  4  PD40         WD40-like Beta Propeller Repeat
        7.2    7.3   0.0        7.2    7.3   0.0    3.4  3  FYDLN_acid   Protein of unknown function (FYDLN_acid)


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.1   0.1   0.00046       1.2      13      38 .]      17      43 ..       8      43 .. 0.64
   2 !   20.3   0.0   2.9e-07   0.00075       4      37 ..      56      90 ..      54      91 .. 0.90
   3 !   21.0   0.1   1.7e-07   0.00044      12      38 .]     121     149 ..     111     149 .. 0.82
   4 !   12.6   0.0   7.7e-05       0.2       3      37 ..     155     190 ..     153     191 .. 0.81
   5 ?   -1.5   0.0       2.2   5.7e+03      15      27 ..     323     335 ..     316     349 .. 0.79
   6 ?   -0.1   0.0      0.78     2e+03       3      15 ..     373     389 ..     372     415 .. 0.80
   7 ?    4.0   0.6     0.039     1e+02      13      33 ..     500     520 ..     490     522 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00046
                EEEEE..EETTSSEEEEEETTSEEEEEE CS
        WD40 13 vtsla..fspdgawlasGsdDgtvriWd 38
                v+s+    +  g++ a+++ D++vriW+
  EEA21966.1 17 VYSVHfdPHVKGRF-ATAGNDNNVRIWK 43
                77775334445555.66666*******6 PP

  == domain 2  score: 20.3 bits;  conditional E-value: 2.9e-07
                EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40  4 lrtltGH.ssvtslafspdgawlasGsdDgtvriW 37
                l tl  H + v+ ++fsp g +las++dDg+v +W
  EEA21966.1 56 LSTLIKHtQAVNVVRFSPKGEMLASAGDDGNVLLW 90
                6788889777************************* PP

  == domain 3  score: 21.0 bits;  conditional E-value: 1.7e-07
                 S..EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  12 s..vtslafspdgawlasGsdDgtvriWd 38 
                 +  +++la+spdg ++++Gs+D+  ri++
  EEA21966.1 121 GaeIYDLAWSPDGVFIITGSMDNVTRIYN 149
                 145************************97 PP

  == domain 4  score: 12.6 bits;  conditional E-value: 7.7e-05
                 EEEEEESSSS.EEEEEEETTSSEEEE.EETTSEEEEE CS
        WD40   3 clrtltGHss.vtslafspdgawlas.GsdDgtvriW 37 
                  +r +  Hs+ v ++a++p + ++a+ +s D++v+i+
  EEA21966.1 155 MVRQIAEHSHyVQGVAWDPLNEFVATqSS-DRSVHIY 190
                 56666679667*************98446.******8 PP

  == domain 5  score: -1.5 bits;  conditional E-value: 2.2
                 EEEEETTSSEEEE CS
        WD40  15 slafspdgawlas 27 
                  l f pdg++l++
  EEA21966.1 323 RLTFTPDGSLLFT 335
                 577999*999976 PP

  == domain 6  score: -0.1 bits;  conditional E-value: 0.78
                 EEEEEESS.SS...EEE CS
        WD40   3 clrtltGH.ss...vts 15 
                 ++ +l GH ++   v++
  EEA21966.1 373 PIAHLPGHkKPsvaVRC 389
                 57899***877844443 PP

  == domain 7  score: 4.0 bits;  conditional E-value: 0.039
                 EEEEEEETTSSEEE.EEETTSE CS
        WD40  13 vtslafspdgawla.sGsdDgt 33 
                  t+l++s+dg  l+ s+s Dg 
  EEA21966.1 500 FTDLSWSSDGLTLImSSS-DGF 520
                 589*********865888.986 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0      0.26   6.7e+02      37      70 ..      13      47 ..       8      60 .. 0.67
   2 !    9.5   0.0   0.00046       1.2      28      64 ..      52      89 ..      30      94 .. 0.71
   3 !   23.8   0.0   1.6e-08   4.2e-05      35      80 ..     118     163 ..     105     165 .. 0.86
   4 !    8.7   0.0    0.0008         2      36      78 ..     161     203 ..     157     211 .. 0.85
   5 !    6.8   0.0    0.0032       8.2      40      72 ..     499     531 ..     469     547 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.26
  ANAPC4_WD40 37 edsevrsLaWkpdgk.lLavaysdgevrlldaesg 70
                 e+  v s+++ p  k  +a a +d++vr+ + es+
   EEA21966.1 13 ENAPVYSVHFDPHVKgRFATAGNDNNVRIWKLEST 47
                 56666677776654325688888888888888765 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00046
  ANAPC4_WD40 28 rvwtl.eedkedsevrsLaWkpdgklLavaysdgevrl 64
                 rv  l +  k+ + v+ ++++p+g++La a +dg+v l
   EEA21966.1 52 RVTYLsTLIKHTQAVNVVRFSPKGEMLASAGDDGNVLL 89
                 34333555688999********************9976 PP

  == domain 3  score: 23.8 bits;  conditional E-value: 1.6e-08
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvks 80 
                   +++ e+ +LaW+pdg ++  +  d+  r+++a++g++v+++  +s
   EEA21966.1 118 RSSGAEIYDLAWSPDGVFIITGSMDNVTRIYNAQTGQMVRQIAEHS 163
                  57899***********************************998776 PP

  == domain 4  score: 8.7 bits;  conditional E-value: 0.0008
  ANAPC4_WD40  36 kedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsv 78 
                  ++++ v+++aW p +++ a   sd +v++++ ++++   sl++
   EEA21966.1 161 EHSHYVQGVAWDPLNEFVATQSSDRSVHIYSLKTKDGQFSLTT 203
                  567789*************************999876666655 PP

  == domain 5  score: 6.8 bits;  conditional E-value: 0.0032
  ANAPC4_WD40  40 evrsLaWkpdgklLavaysdgevrlldaesgkv 72 
                  + ++L+W+ dg  L ++ sdg ++ l+   g++
   EEA21966.1 499 TFTDLSWSSDGLTLIMSSSDGFCSTLSFAPGEL 531
                  5689******************99999887765 PP

>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0     0.022        57      99     119 ..      62      82 ..      11      87 .. 0.73
   2 !   14.6   0.0   9.1e-06     0.023      60     116 ..     122     179 ..     107     190 .. 0.75
   3 ?   -2.6   0.0       1.6   4.2e+03     129     159 ..     480     513 ..     475     517 .. 0.56

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.022
                 EEES--EEEE-TTSSEEEEE- CS
       eIF2A  99 eeqkrNtiffspkgklvllaG 119
                 ++q+ N + fspkg++++ aG
  EEA21966.1  62 HTQAVNVVRFSPKGEMLASAG 82 
                 45788************9998 PP

  == domain 2  score: 14.6 bits;  conditional E-value: 9.1e-06
                 S.EEEEEE-TTSS-EEEEESSSSCEEEEEECS.CEEEEEEEEES..--EEEE-TTSSEEE CS
       eIF2A  60 gpihdvaWspkskefaviyGkmpakvslfdlk.vkviskleeqk..rNtiffspkgklvl 116
                  +i+d+aWsp++    +i G m++ + +++ + ++++ ++ e++     + ++p +++v+
  EEA21966.1 122 AEIYDLAWSPDG--VFIITGSMDNVTRIYNAQtGQMVRQIAEHShyVQGVAWDPLNEFVA 179
                 359999999987..6889999999999999976777777776541146678888777775 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 1.6
                 EEETT...TTEEEEEEE-TT--EEEE-TTSSEEE CS
       eIF2A 129 iwdvk...kkkkiakaeaanatlvewspdgryvl 159
                 i+d++    +  +++++ a+ t++ ws dg  ++
  EEA21966.1 480 IYDTQqqtPLCVVNNLHFATFTDLSWSSDGLTLI 513
                 5666632122345566666667777777775544 PP

>> HIRA_B  HIRA B motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.2   5.7e-06     0.015      10      20 ..     689     699 ..     689     702 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 5.7e-06
      HIRA_B  10 GKKRVaPtLiS 20 
                 +K+R+aPtL+S
  EEA21966.1 689 KKRRIAPTLVS 699
                 5*********9 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.5   0.0    0.0028       7.1     183     214 ..      59      90 ..       3      93 .. 0.76
   2 ?    2.8   0.0     0.018        47     187     215 ..     121     149 ..     101     163 .. 0.81
   3 ?    2.5   0.0     0.022        57     187     211 ..     497     521 ..     469     537 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0028
    Ge1_WD40 183 kieehsliveaafspdGtalatasedGevkff 214
                  i+++  +    fsp G  la a  dG v ++
  EEA21966.1  59 LIKHTQAVNVVRFSPKGEMLASAGDDGNVLLW 90 
                 356666799999***************99776 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.018
    Ge1_WD40 187 hsliveaafspdGtalatasedGevkffq 215
                  ++i + a+spdG  + t s+d + + + 
  EEA21966.1 121 GAEIYDLAWSPDGVFIITGSMDNVTRIYN 149
                 3579999*****************99996 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.022
    Ge1_WD40 187 hsliveaafspdGtalatasedGev 211
                  ++ ++ ++s+dG +l ++s+dG+ 
  EEA21966.1 497 FATFTDLSWSSDGLTLIMSSSDGFC 521
                 36789999***************85 PP

>> PD40  WD40-like Beta Propeller Repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       1.6   4.1e+03      15      24 ..      70      79 ..      70      91 .. 0.71
   2 ?    5.1   0.1     0.009        23       9      22 ..     122     135 ..     118     141 .. 0.76
   3 ?    1.7   0.1       0.1   2.6e+02      15      26 ..     325     335 ..     318     339 .. 0.84
   4 ?    6.2   0.6     0.004        10      15      28 ..     504     517 ..     498     522 .. 0.88

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 1.6
                EE-TTSSEEE CS
        PD40 15 sfSPDGkrla 24
                +fSP G +la
  EEA21966.1 70 RFSPKGEMLA 79
                5888888876 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.009
                 S.EEEEEE-TTSSE CS
        PD40   9 gnegaPsfSPDGkr 22 
                 +++++ ++SPDG  
  EEA21966.1 122 AEIYDLAWSPDGVF 135
                 4677889*****54 PP

  == domain 3  score: 1.7 bits;  conditional E-value: 0.1
                 EE-TTSSEEEEE CS
        PD40  15 sfSPDGkrlaFs 26 
                 +f+PDG +l F+
  EEA21966.1 325 TFTPDG-SLLFT 335
                 89****.66665 PP

  == domain 4  score: 6.2 bits;  conditional E-value: 0.004
                 EE-TTSSEEEEEEE CS
        PD40  15 sfSPDGkrlaFsSd 28 
                 s+S DG +l+ sS+
  EEA21966.1 504 SWSSDGLTLIMSSS 517
                 9**********996 PP

>> FYDLN_acid  Protein of unknown function (FYDLN_acid)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   0.0    0.0028       7.2       3      26 ..     108     131 ..     107     165 .. 0.86
   2 ?   -2.0   0.0       2.2   5.7e+03      25      41 ..     446     462 ..     444     479 .. 0.77
   3 ?   -5.3   7.8         7   1.8e+04      47      48 ..     702     703 ..     645     743 .. 0.51

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0028
  FYDLN_acid   3 kpelGtKriCpscgakFYDLnkdP 26 
                 k+ + +K++C s ga  YDL  +P
  EEA21966.1 108 KETWRVKHMCRSSGAEIYDLAWSP 131
                 78899***************9888 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 2.2
  FYDLN_acid  25 dPivcpkcgeefepeev 41 
                 +P+v+ k+++e + +++
  EEA21966.1 446 KPVVSSKTDNESPSSAF 462
                 7********99988876 PP

  == domain 3  score: -5.3 bits;  conditional E-value: 7
  FYDLN_acid  47 aa 48 
                 +a
  EEA21966.1 702 SA 703
                 22 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (744 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       711  (0.0396564); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.67u 0.31s 00:00:00.98 Elapsed: 00:00:00.47
# Mc/sec: 4741.99
//
Query:       EEA21967.1  [L=311]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        1.2   10.2   3.5         20    6.3   0.2    3.3  2  DUF3298   Protein of unknown function (DUF3298)


Domain annotation for each model (and alignments):
>> DUF3298  Protein of unknown function (DUF3298)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   0.2    0.0011        20       8      27 ..      12      54 ..       8     139 .. 0.49
   2 ?    1.9   0.4     0.026   4.7e+02      10      37 ..     276     303 ..     269     307 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0011
                T.HHHHHHHHHHHHHHHHT.......................C CS
     DUF3298  8 saylqrlakiikeqikken.......................e 27
                +++ ++l+++++  +kke+                       +
  EEA21967.1 12 EDPTKKLDPELQDYLKKERpttyttavepsretptqstqtpsQ 54
                4678999999999999999444444444444443333322220 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.026
                 HHHHHHHHHHHHHHHHTCH-TTS-HCCC CS
     DUF3298  10 ylqrlakiikeqikkenekqqedeyagl 37 
                 y ++ a++ik+q +++++ q+ +++++ 
  EEA21967.1 276 YSEEAAPYIKAQQEAQAKRQERAKSWFG 303
                 7888999*****9999988887777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (311 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1328  (0.0740699); expected 358.6 (0.02)
Passed bias filter:                      521  (0.0290591); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.30s 00:00:00.84 Elapsed: 00:00:00.47
# Mc/sec: 1984.30
//
Query:       EEA21968.1  [L=738]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (738 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1917  (0.106922); expected 358.6 (0.02)
Passed bias filter:                      406  (0.0226449); expected 358.6 (0.02)
Passed Vit filter:                        84  (0.00468515); expected 17.9 (0.001)
Passed Fwd filter:                        34  (0.00189637); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 1.52u 0.40s 00:00:01.92 Elapsed: 00:00:00.59
# Mc/sec: 3789.05
//
Query:       EEA21969.1  [L=302]
Description: GPR/FUN34 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-89  299.0  18.3      2e-89  298.7  18.3    1.1  1  Gpr1_Fun34_YaaH  GPR1/FUN34/yaaH family


Domain annotation for each model (and alignments):
>> Gpr1_Fun34_YaaH  GPR1/FUN34/yaaH family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  298.7  18.3   1.1e-93     2e-89       1     207 []      69     286 ..      69     286 .. 0.98

  Alignments for each domain:
  == domain 1  score: 298.7 bits;  conditional E-value: 1.1e-93
  Gpr1_Fun34_YaaH   1 fggtlnpg.lapvpkrkfaNPaPlgllafalttfvlslvnlgargitepnvvvglalfyGGlvqllaGiwefavgntFgatalssYGgFwlsya 93 
                      fgg+++pg ++pv++rk+aNPaPlgl+afalttfvl+++n+g+r+it+pnvvvgla++yGGlvqllaG+we+avgntFgatalssYGgFw+++a
       EEA21969.1  69 FGGEFQPGlYRPVSDRKIANPAPLGLSAFALTTFVLGCINMGTRDITAPNVVVGLAFGYGGLVQLLAGMWEMAVGNTFGATALSSYGGFWIAFA 162
                      89******************************************************************************************** PP

  Gpr1_Fun34_YaaH  94 ailip.gfgilaaY....eedeeelnnalglyllgwfiftfllllatlrstvalfllfffldltflllaigeltgsak.....vlkAggvfgii 177
                      ++l+p gf i +a     + +++++++ +gl+l+gwfiftf+ll++tlrstva+f+lff+ld++flll+ig+l+++++     ++kAgg+f+++
       EEA21969.1 163 IVLTPgGFAIEEALltadNGSPSMFYDSFGLFLMGWFIFTFILLICTLRSTVAFFSLFFTLDMAFLLLGIGYLVRTDGaptpsIIKAGGFFALL 256
                      *****99*******999888999**************************************************8888888899*********** PP

  Gpr1_Fun34_YaaH 178 aaflawYnalaglatkensyftlpviplpk 207
                      aaflawYnalag+a+++ns+f++pv+++p+
       EEA21969.1 257 AAFLAWYNALAGIADSSNSFFIIPVAHFPW 286
                      *****************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (302 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       619  (0.0345251); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 2085.66
//
Query:       EEA21970.1  [L=689]
Description: hypothetical protein PMAA_057540 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.3e-06   27.5   0.2    1.3e-06   27.5   0.2    1.7  2  Fungal_trans_2  Fungal specific transcription factor domain
  ------ inclusion threshold ------
       0.72    9.4   6.2        1.3    8.6   6.2    1.3  1  SARAF           SOCE-associated regulatory factor of calcium 
        1.2    7.6   7.8          2    6.9   7.8    1.3  1  Macoilin        Macoilin family


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.2       0.3   1.8e+03     206     255 ..     114     166 ..     112     199 .. 0.63
   2 !   27.5   0.2   2.1e-10   1.3e-06      16     131 ..     271     392 ..     256     408 .. 0.80

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.3
  Fungal_trans_2 206 Larekrsarkd..seleplsileeaseleqrll.swkprssdlepdldetera 255
                     L +++r+++++  ++l  +  +  as++ ++++ s+ ++ss++++d++++++ 
      EEA21970.1 114 LENTRRYNKSKtwKNLAYRPESMAASKFSRAIEsSIPSPSSSSTSDRSSSKSS 166
                     56666666666664444444555555555555555555555555555444444 PP

  == domain 2  score: 27.5 bits;  conditional E-value: 2.1e-10
  Fungal_trans_2  16 pvpes.snpfrkvllplalsnkallhallalsafhl..........qskgpkds......lereakrykslalkelqealaelsstlsrnekykd 93 
                     p+ ++  +  rk  + la+s++++l+a++  + ++                         l  +++r + ++++++++ l+ + s +s     ++
      EEA21970.1 271 PFMNHgVAKLRKHWISLAQSSPSVLYACITSAVTNKslmtgdffadP------AtqrnslLILDRLRNRGETISLINRDLSSVPSATS-----DA 354
                     444444567889999*********************66665555542......0444446778999**********************.....** PP

  Fungal_trans_2  94 iLaaiLllcsieissgdvsdwrvhLeaatsliksrggs 131
                      + a+ ll+s+e+  ++++d   hL++ +++++ r++ 
      EEA21970.1 355 CISAVSLLISVEVTGSNPQDIAPHLHGLRKMVSLRKNF 392
                     ***********************************998 PP

>> SARAF  SOCE-associated regulatory factor of calcium homoeostasis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   6.2   0.00021       1.3     212     322 ..      45     162 ..       6     170 .. 0.62

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00021
       SARAF 212 eeeqddpPppysltksqkpssssessqqgeqeeswrpGFWtGlatGaaaG............YlagrrraqneeteeeekeksssWgsssegsssssss 298
                 + +qd+pPp +++++++k +     s q+++ +s+ p FW      ++               ++++++++++ +++++++ks++W++ +  ++s ++s
  EEA21970.1  45 SLNQDEPPPKNEVNDDDKAKM----SPQQKTGNSRSPLFWVNSDPQTVQKgsreetlkrirsHVMSEHNRKKRLENTRRYNKSKTWKNLAYRPESMAAS 139
                 334478888886555555333....44555678999****877666665435555666666566888888888888888999****9998666666666 PP

       SARAF 299 ssssssassssssssssssstres 322
                 ++s++ +ss  s ssss+s +r+s
  EEA21970.1 140 KFSRAIESSIPSPSSSSTS-DRSS 162
                 6555444443333333332.2222 PP

>> Macoilin  Macoilin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   7.8   0.00034         2     199     344 ..      48     191 ..      39     265 .. 0.65

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.00034
    Macoilin 199 qqaLPkeqqlldkeereaeeqlaaakelvevdpvalsknnhslnkkdsslklpeleyrekkksakssrsdskkkhehnesvdsklqekeymenkskskr 297
                 q+  P+ +++ d ++ + + q+++ +  +  +   ++ + ++ +k + +++l  + ++  ++ ++++r +++++++++++ ++ + + e m+    s+ 
  EEA21970.1  48 QDEPPPKNEVNDDDKAKMSPQQKTGNSRS--PLFWVNSDPQTVQKGSREETLKRIRSHVMSEHNRKKRLENTRRYNKSKTWKNLAYRPESMAASKFSRA 144
                 55556667788888877777777766666..45566777777777777888888888888888888888888888888888888888888887777777 PP

    Macoilin 298 lsksessgsesellveesvkskssssssssnknskkasagsagssns 344
                 +++s  s s+s++  ++s+ks+ss++  ++++  + +  +s+gs  s
  EEA21970.1 145 IESSIPSPSSSSTSDRSSSKSSSSPEIRETSPPDSFKIPKSTGSMAS 191
                 77777777777777777777777777777664333333333332222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (689 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       760  (0.0423894); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.67u 0.28s 00:00:00.95 Elapsed: 00:00:00.45
# Mc/sec: 4640.42
//
Query:       EEA21971.1  [L=244]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-28  100.0   0.0    1.4e-28   99.7   0.0    1.1  1  adh_short       short chain dehydrogenase
      1e-24   87.4   0.5    1.3e-24   87.1   0.5    1.1  1  adh_short_C2    Enoyl-(Acyl carrier protein) reductase
    2.5e-08   34.1   0.1    3.8e-08   33.4   0.1    1.4  1  KR              KR domain
    2.8e-05   24.1   0.2    6.4e-05   22.9   0.1    1.9  2  NAD_binding_10  NAD(P)H-binding
     0.0013   18.2   0.1     0.0026   17.2   0.1    1.5  1  Epimerase       NAD dependent epimerase/dehydratase family
     0.0051   16.4   0.0     0.0079   15.8   0.0    1.3  1  NmrA            NmrA-like family


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.7   0.0   4.7e-32   1.4e-28       1     187 [.       5     197 ..       5     204 .. 0.89

  Alignments for each domain:
  == domain 1  score: 99.7 bits;  conditional E-value: 4.7e-32
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEEEESC.HHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHH.SSESEEEE---S.S--SSGGGC CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvvvdrs.eekleevakelkeegakalaiqvDvtdreevealvekavkkl.gkldvLvnNAGi.tgsgpfsel 96 
                 k+ l++Gas+GIG+++++++++ G +v+++ r+ ++++ ++a++      ++ ++++Dv+ +e+++ ++ + v    +++d  v NAGi + ++ + e+
  EEA21971.1   5 KTWLIVGASRGIGLEFVRQIVTLGHRVIATVRNpNSDIDALAQSAP---GQVRVLTCDVSREESINGFIHQFVHSGeQRIDYAVINAGIlKYPNRTLEM 100
                 5779*************************65550556666666655...57******************999888779***********988999**** PP

                 SHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-T.....TBHHHHHHHHHHHHHHHHHHHHHGGGT..EEEEEEEESSBSSHHH CS
   adh_short  97 seeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpva.....gvaaYsAsKaavagltrslakelaptg..irvnavaPGlvdTdma 187
                 + + +   +++N  g++ +++ +l+   +   G+I ++sS  g  + +     g+aaY+AsKaa+++  r +a+el++++    + a++PG v+Tdm 
  EEA21971.1 101 TFDHFATHLHTNTIGPIIVAQKLLQL-SSVAIGTIAFMSSDSGSTARFlafedGFAAYGASKAALNQALRHMAEELKRKQrdTIILALHPGEVATDMG 197
                 **********************9998.99**************877642333379**********************999999999**********96 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.1   0.5   4.2e-28   1.3e-24       1     179 [.      11     197 ..      11     231 .. 0.90

  Alignments for each domain:
  == domain 1  score: 87.1 bits;  conditional E-value: 4.2e-28
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSEE..EE--TTSHHHHHHHHHHHHHHH.SSEEEEEE-----EGCSS-GGGH-HHH CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneeakkrveelaeelgaev..lecDVtdeeqvealveevvekf.gklDilvnnagiapklkgpfletsree 94 
                   Ga +gIG + ++++   G +v++t +n ++  ++++la++ + +v  l cDV++ee+++ ++ + v++  +++D++v nagi +   +++le++ ++
    EEA21971.1  11 GASRGIGLEFVRQIVTLGHRVIATVRNPNS--DIDALAQSAPGQVrvLTCDVSREESINGFIHQFVHSGeQRIDYAVINAGILKY-PNRTLEMTFDH 104
                   999*************************98..899999999877444*****************9999989*************9.*********** PP

                   HHHHHHHHTHHHHHHHHHHHHHCTSC.CEEEEEEEGGGTSB.....STTTTHHHHHHHHHHHHHHHHHHHHGG..GTEEEEEEEE--BHCTGG CS
  adh_short_C2  95 fdraldvnlyslfllakaalplmkeg.gsivnlssvgaerv.....vpnynaygaaKaalealtrylAvelgp..kgiRvNavspgpikTlaa 179
                   f++ l++n+ + + +a+ +l+l     g i  +ss +++ +      ++ +ayga+Kaal++  r +A el +  +   + a +pg ++T++ 
    EEA21971.1 105 FATHLHTNTIGPIIVAQKLLQLSSVAiGTIAFMSSDSGSTArflafEDGFAAYGASKAALNQALRHMAEELKRkqRDTIILALHPGEVATDMG 197
                   *********************998888*********988764433356777********************9844567788999999999984 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.4   0.1   1.3e-11   3.8e-08       2     159 ..       6     167 ..       5     189 .. 0.74

  Alignments for each domain:
  == domain 1  score: 33.4 bits;  conditional E-value: 1.3e-11
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHT.T-EEEE----TT-HHHHHHHHHHHHHHS.S---EEEE------.---T CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaeleal.gaevevvaaDvsdkdavealleeikaee.ppikGvihaAgvlr.dkll 97 
                 t li+G+  g+Gle++r+++  g r +  + R+  +++     i++l+++   +v+v+ +Dvs +++++  ++++ +++ ++i   +  Ag+l+  +  
  EEA21971.1   6 TWLIVGASRGIGLEFVRQIVTLGHRVI-ATVRN--PNS----DIDALAQSaPGQVRVLTCDVSREESINGFIHQFVHSGeQRIDYAVINAGILKyPNRT 97 
                 68*********************9865.56688..333....46677666366***********************99999***999999999867999 PP

                 TT--HHHHHHHHTTTTHHHHHHHHHTTT...S--SEEEEEEEHHHHH-.....-TT-HHHHHHHHHHHHH CS
          KR  98 eemtaedleqvlapKvkGawnLhelled...esldffvlfSSiagllg.....sagqanYaaaNaflDal 159
                  emt +++++ l+    G   + + l +     +  + ++SS +g +      + g a+Y a  a l++ 
  EEA21971.1  98 LEMTFDHFATHLHTNTIGPIIVAQKLLQlssVAIGTIAFMSSDSGSTArflafEDGFAAYGASKAALNQA 167
                 9*********999988887766665555333455566666665554331111134556666655555554 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.1   2.1e-08   6.4e-05       1      56 [.      11      68 ..      11     186 .. 0.90
   2 ?   -1.5   0.0      0.65   1.9e+03      61      90 ..     180     228 ..     159     231 .. 0.47

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 2.1e-08
                    TTTSHHHHHHHHHHHHC-T-EEEEEETTH.HHCHHHH..CTTTCEEEE--TT-CCHHHH CS
  NAD_binding_10  1 GAtGkvGrllvkellargghevtalvRnp.eklaele..aeeglevvegdvtdvedlae 56
                    GA+ ++G + v++++   gh+v a vRnp +++++l+  a  +++v++ dv+ +e++  
      EEA21971.1 11 GASRGIGLEFVRQIVTL-GHRVIATVRNPnSDIDALAqsAPGQVRVLTCDVSREESING 68
                    9****************.5*********845788887334589**********999976 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.65
                     -SEEEES-...................--TCCHHHHHHHHHHHHHHCT- CS
  NAD_binding_10  61 adaVvsal...................ggggkdeegaknivdaakeagv 90 
                      d+++ al                   gg+ + ee++++++d+++ +++
      EEA21971.1 180 RDTIILALhpgevatdmgnlgiaweisGGQITAEESVVAMIDVVQSKNI 228
                     4455555522222222222222222212222244446666666666665 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.1   8.9e-07    0.0026       1     159 [.       7     174 ..       7     188 .. 0.68

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 8.9e-07
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC....EEEE--TT-HHHHHHHHHH......HT-SEEEE--S.---HHHHHHSHHHHH CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl....elveldltdrsalerlfke......eqpdavihlAa.vggvaassedpadfi 88 
                 +l++Ga+  iG  +v+++ + g++vi+  r+++++  a+ + +    ++ ++d+  +++++ ++++      +++d+ +  A+  + ++++ e   d +
  EEA21971.1   7 WLIVGASRGIGLEFVRQIVTLGHRVIATVRNPNSDIDALAQSApgqvRVLTCDVSREESINGFIHQfvhsgeQRIDYAVINAGiLKYPNRTLEMTFDHF 105
                 59*****************************8888777777779999************9999986222221355655555454555555555554444 PP

                 HHHTHHHHHHHHHHHHHTCTEEEEEEEGGGGTSCSS.S.SBSTCSTTS--.--SSHHHHHHHHHHHHHHHHHHH CS
   Epimerase  89 eknlqgtlnlleaarkagvkrllflsSsevYGkdae.q.pkeettltgpl.kpnspYaaaKlageklveayaaq 159
                  ++l    +         +++ll+lsS+++    a  +    +t+    +     +Y+a+K+a  + ++ +a++
  EEA21971.1 106 ATHL----HTNTIGPIIVAQKLLQLSSVAIGT-IAFmSsDSGSTARFLAFeDGFAAYGASKAALNQALRHMAEE 174
                 3222....222222222334677777765533.22212124455555577888999999999999999998876 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   2.7e-06    0.0079       2      62 ..       8      70 ..       7      75 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 2.7e-06
                EESSTTSHHHHHHHHHHHHHT-EEEEEES-S-SHHHHHHHHST..TEEEES-TT-HHHHHHHH CS
        NmrA  2 lviGaTGrqGksvvrallkaghkvralvRdtkselakslkeaG..velvkgdlddkeslveal 62
                l++Ga+  +G  +vr ++  gh+v a vR+++s+  +  ++a+  v ++  d+  +es++  +
  EEA21971.1  8 LIVGASRGIGLEFVRQIVTLGHRVIATVRNPNSDIDALAQSAPgqVRVLTCDVSREESINGFI 70
                799****************************99876655655533455689999999887666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (244 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       639  (0.0356406); expected 358.6 (0.02)
Passed bias filter:                      560  (0.0312343); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.49u 0.29s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 1664.60
//
Query:       EEA21972.1  [L=190]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.3e-21   76.8   0.0    2.6e-21   76.6   0.0    1.1  1  Isochorismatase  Isochorismatase family


Domain annotation for each model (and alignments):
>> Isochorismatase  Isochorismatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.6   0.0   1.4e-25   2.6e-21       1     161 [.       4     156 ..       4     178 .. 0.85

  Alignments for each domain:
  == domain 1  score: 76.6 bits;  conditional E-value: 1.4e-25
  Isochorismatase   1 talvviDmqndfveegvkeseeisavveninkllkaarkagip.....viftrdvheleevkgdlderkaaphfkpgttgaelvpelaplegdv 89 
                      tal+viD+qn+++ + + e+++++++ ++++  lk++r +  +     v++++++ +           + ++ ++++++ ++lv +  pl +++
       EEA21972.1   4 TALFVIDVQNGLA-NSTTEIPQAPRIRQAAETILKSVRGNVSHvkrpeVFIVQHEES-----------PESGDLVRDSEPWKLVFS--PLGDER 83 
                      89***********.***********************74442233334777777777...........***************966..999*** PP

  Isochorismatase  90 vvdKtrfsaf.agtdldeiLkelgiktivlaGiatdvCVeatardaldlGyevvvvsDAvaalspelhdaalk 161
                      +v K++ + f +++dl  +L+ + i t+v +Gi  ++CV+ t + al  G++v++++ A ++++  +  ++  
       EEA21972.1  84 LVSKHTCNTFeSNPDLTTQLRTQDISTLVMCGIQSEYCVRGTSLGALAAGFNVILLQGAHSTYDDAGSGKSAT 156
                      **********99***************************************************9665444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (190 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       389  (0.0216967); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.49
# Mc/sec: 1174.07
//
Query:       EEA21973.1  [L=190]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.3e-21   76.8   0.0    2.6e-21   76.6   0.0    1.1  1  Isochorismatase  Isochorismatase family


Domain annotation for each model (and alignments):
>> Isochorismatase  Isochorismatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.6   0.0   1.4e-25   2.6e-21       1     161 [.       4     156 ..       4     178 .. 0.85

  Alignments for each domain:
  == domain 1  score: 76.6 bits;  conditional E-value: 1.4e-25
  Isochorismatase   1 talvviDmqndfveegvkeseeisavveninkllkaarkagip.....viftrdvheleevkgdlderkaaphfkpgttgaelvpelaplegdv 89 
                      tal+viD+qn+++ + + e+++++++ ++++  lk++r +  +     v++++++ +           + ++ ++++++ ++lv +  pl +++
       EEA21973.1   4 TALFVIDVQNGLA-NSTTEIPQAPRIRQAAETILKSVRGNVSHvkrpeVFIVQHEES-----------PESGDLVRDSEPWKLVFS--PLGDER 83 
                      89***********.***********************74442233334777777777...........***************966..999*** PP

  Isochorismatase  90 vvdKtrfsaf.agtdldeiLkelgiktivlaGiatdvCVeatardaldlGyevvvvsDAvaalspelhdaalk 161
                      +v K++ + f +++dl  +L+ + i t+v +Gi  ++CV+ t + al  G++v++++ A ++++  +  ++  
       EEA21973.1  84 LVSKHTCNTFeSNPDLTTQLRTQDISTLVMCGIQSEYCVRGTSLGALAAGFNVILLQGAHSTYDDAGSGKSAT 156
                      **********99***************************************************9665444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (190 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       389  (0.0216967); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.41
# Mc/sec: 1377.37
//
Query:       EEA21974.1  [L=612]
Description: ENTH domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.1e-64  215.7   0.5    7.7e-64  215.3   0.5    1.1  1  ANTH      ANTH domain
    8.2e-07   29.1   0.0    8.5e-06   25.8   0.0    2.2  2  ENTH      ENTH domain


Domain annotation for each model (and alignments):
>> ANTH  ANTH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  215.3   0.5   8.6e-68   7.7e-64       2     277 .]       5     262 ..       4     262 .. 0.97

  Alignments for each domain:
  == domain 1  score: 215.3 bits;  conditional E-value: 8.6e-68
                 HHHHHHHHT-SSS---HHHHHHHHHHHCST.TS-HHHHHHHHHHHCTSS.SHHHHHHHHHHHHHHHHHS-CHHHHHHHHTT-----TT---TSHHHSTH CS
        ANTH   2 levavvKAtshdevPpkekhvreilvltss.rekvaalvwalsrrlkltrnwvvalKaLilvHklLreGhpsveqellsarrrisellnlssfddsssk 99 
                 +e++v++At+++ +Ppk k++++ilv+t+s ++ v +++++l  rl+++ +w++++K+Li++H ++reG ++++ e+l+ + r   ++ +s+       
  EEA21974.1   5 FEKSVKGATKIKLAPPKSKYIEHILVATRSgEAGVGEIFRTLQFRLRDS-TWTIVFKSLIVLHMMIREGAENATLEYLADNPRKVAISSFSE------- 95 
                 689**********************************************.********************************9999999999....... PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHSS-...CCCS--S.....TTSHCC.C--HHHHHHHHHHHHHHHHHHHTT---GGG--SHHHHHHHHHHHHHHHH CS
        ANTH 100 swdysafiraYakyLderlefhrklkvdkgelereeegslvavedpnerktlsmeklldkieklqklldrllkckptgnalsnevilaalvllvkeslk 198
                  ++++ +ir+Y++yL  r++ + ++kvd   + r+ +g         +r  +  + ll++ e +qk++++llkc+   ++ +ne++l+a++ll +++l+
  EEA21974.1  96 VQAQGHNIRRYSDYLIARAKAFADTKVD---HVRSGQGR-------LKR-LTVSKGLLRETEVVQKQIKALLKCDLLTDEVENEITLTAFRLLTMDLLA 183
                 899*************************...88888882.......334.788899******************************************* PP

                 HHHHHHHHHHHHHHHHCCS-CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCT--GGG.S--GGGS-CHHCCCCCHHHHC CS
        ANTH 199 lYkaineglinLlekffelskheadkaldiykrfskqfeelkeFyevckslgilrsleiPelekippnllealeeflrd 277
                 lY  +neg in+le++fe+s++++++al+iyk+fs q+ee+++F+ v++ ++++++leiP+l++++++l++ le+ l+d
  EEA21974.1 184 LYSVMNEGTINVLEHYFEMSRPDSERALQIYKTFSAQTEEVVKFLGVARHFEYATRLEIPNLKHASTDLTQLLEDDLKD 262
                 **************************************************************************98875 PP

>> ENTH  ENTH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   0.0   9.5e-10   8.5e-06       3     117 ..       4     112 ..       2     118 .. 0.84
   2 ?    0.5   0.0     0.063   5.7e+02      92     122 ..     232     259 ..     207     261 .. 0.72

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 9.5e-10
                 HHHHHHHHHTSSSSSS--HHHHHHHHHHTTSH.HHHHHHHHHHHHHHHH--GGGHHHHHHHHHHHHHHHHHS-HHHHHHH.HHTHHHHHGGGG---B-T CS
        ENTH   3 eteskvreatnndpwGpsnkllteiarltysk.kelseiisvitkrLqnnkgkewrsvlKaLtlieYLlknGseqvidwl.kenisiiktlsefkyide 99 
                 ++e+ v+ at+ +   p++k +++i  +t s    + ei  +++ rL   +++ w  v+K+L++++ ++++G e+   +   +n      +s+f    +
  EEA21974.1   4 NFEKSVKGATKIKLAPPKSKYIEHILVATRSGeAGVGEIFRTLQFRL---RDSTWTIVFKSLIVLHMMIREGAENATLEYlADNPR-KVAISSF----S 94 
                 6899**************************987889**********9...999*********************776666244444.4455666....3 PP

                 TS-B-HHHHHHHHHHHHH CS
        ENTH 100 egkdeglniRkkakkiis 117
                 e + +g+niR+ ++ +i+
  EEA21974.1  95 EVQAQGHNIRRYSDYLIA 112
                 357799999999998886 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.063
                 GG---B-TTS-B-HHHHHHHHHHHHHHHT-H CS
        ENTH  92 sefkyideegkdeglniRkkakkiisllede 122
                 ++f+y     + e+ n ++ + ++++lled+
  EEA21974.1 232 RHFEY---ATRLEIPNLKHASTDLTQLLEDD 259
                 34433...556677799************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (612 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       538  (0.0300073); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.29s 00:00:00.96 Elapsed: 00:00:00.50
# Mc/sec: 3652.43
//
Query:       EEA21975.1  [L=689]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (689 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       514  (0.0286686); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 4465.78
//
Query:       EEA21976.1  [L=161]
Description: 40S ribosomal protein S11 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.9e-33  112.5   0.4    1.4e-32  111.8   0.4    1.3  1  Ribosomal_S17_N  Ribosomal_S17 N-terminal
    1.2e-26   92.6   0.4    2.3e-26   91.7   0.4    1.5  1  Ribosomal_S17    Ribosomal protein S17


Domain annotation for each model (and alignments):
>> Ribosomal_S17_N  Ribosomal_S17 N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.8   0.4   1.6e-36   1.4e-32       1      69 []       8      76 ..       8      76 .. 0.91

  Alignments for each domain:
  == domain 1  score: 111.8 bits;  conditional E-value: 1.6e-36
                     --SSS----SS--------------....--------TT----GGGGS-----TTSSSSSS----S-EE CS
  Ribosomal_S17_N  1 qterafqkQetvflnkkkskeekkkkkkkkryvknvglgfktPkeAiegtYiDkKCPFtGnvsirGriL 69
                     q+erafqkQ+++f n k+++++k+  k  +r++k+vglgf+tPk+Aieg+YiDkKCPFtG vsirGriL
       EEA21976.1  8 QSERAFQKQPHIFANGKTKAKSKRVGKGGRRWYKDVGLGFRTPKNAIEGSYIDKKCPFTGLVSIRGRIL 76
                     89***************555555555555***************************************8 PP

>> Ribosomal_S17  Ribosomal protein S17
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.7   0.4   2.5e-30   2.3e-26       1      67 [.      78     145 ..      78     146 .. 0.98

  Alignments for each domain:
  == domain 1  score: 91.7 bits;  conditional E-value: 2.5e-30
                    EEEEE--STTEEEEEEEEEEEETTTTEEEEEEEEEEEE-TTTS.--TT-EEEEEEECECSSSEEEEEE CS
  Ribosomal_S17   1 GvVvsdkmdkTvvVrverlvkhpkykkyvkrrkkylahdenns.vkvGDiVrieecrPlSktkrfvvv 67 
                    G+Vvs+km++T ++r+e+l++ pky +y+kr+k++ ah ++ + v++GD V++++crPlSkt+rf+v+
     EEA21976.1  78 GTVVSTKMHRTLIIRREYLHYVPKYDRYEKRHKNLAAHVSPAFrVEEGDQVTVGQCRPLSKTVRFNVL 145
                    99****************************************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (161 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       411  (0.0229238); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.44
# Mc/sec: 1109.67
//
Query:       EEA21977.1  [L=1507]
Description: chromosome segregation protein Spc105, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
          0 1177.8  58.8          0 1176.9  58.8    1.5  1  Spc7_N         N-terminus of kinetochore NMS complex subunit 
   6.1e-126  419.5   9.8   6.1e-126  419.5   9.8    2.2  4  Spc7           Spc7 kinetochore protein
  ------ inclusion threshold ------
       0.32   10.6  13.5      0.045   13.3   4.5    3.5  3  PI3K_P85_iSH2  Phosphatidylinositol 3-kinase regulatory subun


Domain annotation for each model (and alignments):
>> Spc7_N  N-terminus of kinetochore NMS complex subunit Spc7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ! 1176.9  58.8         0         0       1     925 []      25     894 ..      25     894 .. 0.96

  Alignments for each domain:
  == domain 1  score: 1176.9 bits;  conditional E-value: 0
      Spc7_N   1 lDkeNvttdisasqklastakaaakdkksRsKSlGPGGLdaLkdsngnrrkstaafplkSILKPtiPvsPirnIPsfeetrkrtparspqrnskkeesn 99 
                 +D+eN+ttdi+a++++a+  +  ++dkksRsKSlGPGGLdaL++ +gnrrkst+a+plkSILKPtiPvsPirnIPsf+e+r+++           + ++
  EEA21977.1  25 MDQENATTDITAMKRFATDGRGLTRDKKSRSKSLGPGGLDALQSLSGNRRKSTMALPLKSILKPTIPVSPIRNIPSFDESRRQQN----------TAKQ 113
                 79*******************************************************************************9943..........3455 PP

      Spc7_N 100 skgkeellidlstpaeasvvgtenlanPFdtfnass.irvalrteeeeqaaarEreekerrerEkkaileqReARRKSlAnRRVSFApEATLHTwnvve 197
                 s+++e++lid+stpa+asv+g+e+l nPFd fnass ir            a+Ereeker+erEkkaileqReARRKS+A+RRVSFApEATLHTwnvve
  EEA21977.1 114 SQADEGMLIDFSTPAKASVTGAEQLDNPFDGFNASSaIR-----------DAKEREEKERKEREKKAILEQREARRKSMASRRVSFAPEATLHTWNVVE 201
                 566789******************************788...........489********************************************** PP

      Spc7_N 198 laeDSTsSsasnstRRaSsltaessaaeakkeseppsspeeqaeedea.esPaenqdlqqkkkrrrsstlaealsdadadealsSspfsgdsadgseet 295
                 l+eDSTsSsa+nstRRaS+l++++++a       p+++pe+++e+++a +sP++   +qq                    ++lsSspfsg+s+ gs+ t
  EEA21977.1 202 LIEDSTSSSAANSTRRASTLANSTNQA-------PAEAPEAYEEDPDAaFSPIQPGLHQQ-------------------PSELSSSPFSGSSVGGSDGT 274
                 ***********************9999.......9999*9999999888****9977665...................468**************955 PP

      Spc7_N 296 eleeeaeedddsnsdssddddestamsldemtsrsvasaqsdeSstsssarldeaLrqAakeAGtrgidydengdlsmeiadqeitgaFqpWikKgqrs 394
                   ++ a+++dd++sds+d+d estamsld++t+r++ ++  d+S tsss+rl+eaLrqAa+eAGt g+ ++e++d+smeiadqeitgaF+pWi+Kgqr+
  EEA21977.1 275 --QSPAKDMDDADSDSEDFDAESTAMSLDDITARTSGTTPVDDS-TSSSERLNEALRQAAREAGTSGVGIEEDDDVSMEIADQEITGAFKPWIQKGQRI 370
                 ..599***************************************.****************************************************** PP

      Spc7_N 395 efdaedlsarlDqenvnpsklsatkpesseakeaaad..eqdedlsmdvTkavGgIiskkskerresvarrksigeetnlddqtmeltnvvGgIaqses 491
                 +fd+ed+sa +Dqen+np++ ++++ ++++++++a+d  +++e+lsm++T+avG+I+     ++++s ++rksi+e+tn+d+qtmelt+vvGgI+q++s
  EEA21977.1 371 SFDMEDMSAIHDQENINPYQ-HSNSYDHADTDDEAEDdyNENEELSMEITTAVGKIL----GNSQNSRNSRKSISEQTNYDEQTMELTKVVGGIEQQQS 464
                 ******************99.888888888888888867899***************....56788999****************************** PP

      Spc7_N 492 pakeldaesdidedEemtmefTsvlGgvlnksafrakkaee......ekeeseeserqeieedagdedddadmeiTgavGgil.paieeqtepededqT 583
                 p+k+ d++++++e+E+mtmefTsv+Ggvl+k+  + ++a++      + +e+++++++e+ +d+gd+d ++dme+TgavGgil p +ee+t+++d  +T
  EEA21977.1 465 PTKS-DIDNNMEENEDMTMEFTSVIGGVLSKHVPGIARANDgivaeaQGREDTSRDFSEWGSDDGDDDAGMDMEFTGAVGGILsPIMEERTGSQD-GYT 561
                 ****.******************************9999999998766666999*****************************667799999999.*** PP

      Spc7_N 584 agmelTtavGkIlppeakesekeqekveaeaeseaaqlassPfqenvkaspakkpaskhvaavasesgsPslasvrsrstrqslsrresttptsksrqs 682
                 agm++T+avG+Ilpp  ++s+k+q+k+ +e+es++ qlassPfq +v asp+k   ++h+a++ase+gsPslasvrsr+tr+s  ++++  + s srq 
  EEA21977.1 562 AGMDITAAVGRILPPGLATSDKSQAKQLMELESDSGQLASSPFQLQVPASPPKPLPAHHIAPIASETGSPSLASVRSRRTRRS--SASPGIHLSPSRQV 658
                 *********************************************************************************88..58899999****** PP

      Spc7_N 683 sPvksk.stpskqktpraarpstpaktppsskvksrsaSpkklfkselkesaskkkspksksLFekdaetGestPsfvLkpkekrrssglGidkeGlgS 780
                 +P+k+k +tpskq+tp++ rp+tp ktppss++++rsaSpkklf++e+k+sask++sp ++sLFe ++ +G+stP+f+L+p+  r+ssglGidk+GlgS
  EEA21977.1 659 TPNKNKpRTPSKQATPQPPRPTTPGKTPPSSNISFRSASPKKLFREEIKASASKAQSPGRRSLFEASK-NGDSTPAFILRPHP-RQSSGLGIDKKGLGS 755
                 *****967**********************************************************88.************99.*************** PP

      Spc7_N 781 PrvaeildrRrsigedaqeFvpqekekrgvrFedpskleeevdrereeeekresgiieaeqleerdatlnLkdlIssLtPKknklkgRKSLhVGaArGl 879
                 P+vaeildrRrsigedaqeFvpqe ++r++rFedp++l+eevdrereeee+re+   +a q +e d+t+nL+dlIssLtPKk+++  RKSLhVGaArGl
  EEA21977.1 756 PKVAEILDRRRSIGEDAQEFVPQEPSPRRIRFEDPIRLHEEVDREREEEEQREER-NSALQVSELDPTSNLRDLISSLTPKKRQI--RKSLHVGAARGL 851
                 ******************************************************9.57789***********************9..************ PP

      Spc7_N 880 LGKRPaELDeddedeedstpKRLkgreaSPVKnirLpaPpskdetv 925
                 LGKRPaELD+++e   d++pKR+++ +aSPVK i+LpaPpskdetv
  EEA21977.1 852 LGKRPAELDDEEE---DESPKRIRAANASPVKPIKLPAPPSKDETV 894
                 *********6655...569**************************8 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.8      0.78   4.7e+03     221     246 ..     156     181 ..     147     215 .. 0.57
   2 ?   -4.4   1.3       1.1   6.9e+03     224     260 ..     417     453 ..     378     481 .. 0.54
   3 ?   -5.1   1.2       1.9   1.2e+04     176     202 ..     794     820 ..     792     841 .. 0.50
   4 !  419.5   9.8    1e-129  6.1e-126       2     309 ..     970    1290 ..     969    1291 .. 0.99

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 0.78
        Spc7 221 elaelqeqleeleekieelkeqksel 246
                 e +e++++  e+++ +e+ +++++++
  EEA21977.1 156 EREEKERKEREKKAILEQREARRKSM 181
                 33333333333333333333333333 PP

  == domain 2  score: -4.4 bits;  conditional E-value: 1.1
        Spc7 224 elqeqleeleekieelkeqkseleeeiaeaervleec 260
                 e ++ + ++  + ++ +++++++ e+++  e+++e +
  EEA21977.1 417 EITTAVGKILGNSQNSRNSRKSISEQTNYDEQTMELT 453
                 3333444444444444444444444444333333322 PP

  == domain 3  score: -5.1 bits;  conditional E-value: 1.9
        Spc7 176 kaeleeeleklqeaaeelesidkeeLe 202
                 ++e+ +e e++++++e  ++++  eL 
  EEA21977.1 794 HEEVDREREEEEQREERNSALQVSELD 820
                 455555656555555554444444443 PP

  == domain 4  score: 419.5 bits;  conditional E-value: 1e-129
        Spc7    2 evepisLqdFLnmtgIrFmdltttkrrstiaptaeek........eeeekisledyvvAaactvPlLeLYqhscreLkkyisegrkiireieeetle 90  
                  e epi+Lq+FLn t+I+Fm+ltttkrr+t++ ++ +          e+ ++sled+v+A++ctvP+LeLYqhscreLk+yisegr+iir+ieeetl+
  EEA21977.1  970 EWEPIQLQEFLNLTNIHFMELTTTKRRHTTVAGNDRTadisgsrtVETGSVSLEDCVAAGFCTVPMLELYQHSCRELKSYISEGRQIIRSIEEETLA 1066
                  78******************************999889******99*************************************************** PP

        Spc7   91 enPpLfreYmeadpdvkalmdnqfklvKtnarlqakkdWYeWRmqllegLkegleenlegleedkelLekqeeeldellpeleeekaeleeeleklq 187 
                  enPpLfreY++a+pd+++lmdnqf++vKt+arl++k++WYeWRm+llegLkegl++++e++++d++lL++qe+ l++++pel+e+++ l +e+ ++q
  EEA21977.1 1067 ENPPLFREYVTARPDIRLLMDNQFRNVKTHARLLSKAMWYEWRMKLLEGLKEGLDRHVEEMQADDSLLSQQEAILQSVVPELVEKRSLLDSEASRMQ 1163
                  ************************************************************************************************* PP

        Spc7  188 eaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaervleeckgwsesevsrlkeevkaleeltgw 284 
                  e ++e+e+id++eL+ +re+la+++ae+e+kk++l+++qe+l++++++ie+ +e k+e+ e+i+eaerv+eec+gws +ev++lk++v++le +tgw
  EEA21977.1 1164 EIVDEMENIDPDELRMARERLAKADAEVERKKRQLEQMQEDLQNKNDTIEAGTELKTEFLEQIREAERVREECRGWSIKEVNSLKDSVQMLEVQTGW 1260
                  ************************************************************************************************* PP

        Spc7  285 kivsls.....gstleltyrselevsfdls 309 
                  +ivs+      g+ ++l+y++elev+f+++
  EEA21977.1 1261 SIVSAMtqeltGPGMTLRYKDELEVKFYPK 1290
                  *****999999999*************985 PP

>> PI3K_P85_iSH2  Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   0.0       1.9   1.1e+04     101     115 ..     317     331 ..     312     333 .. 0.79
   2 ?    1.1   0.2     0.043   2.6e+02      64      92 ..     787     815 ..     785     848 .. 0.75
   3 ?   13.3   4.5   7.6e-06     0.045      19      94 ..    1177    1255 ..    1166    1260 .. 0.91

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 1.9
  PI3K_P85_iSH2 101 hsskekLeedlkqqk 115
                     ss+e+L+e+l+q +
     EEA21977.1 317 TSSSERLNEALRQAA 331
                    689999999999876 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.043
  PI3K_P85_iSH2  64 FeeqiklqekfskeaqehEieklqenleq 92 
                    Fe+ i+l+e++ +e +e+E+++  ++  q
     EEA21977.1 787 FEDPIRLHEEVDREREEEEQREERNSALQ 815
                    99************987777654444433 PP

  == domain 3  score: 13.3 bits;  conditional E-value: 7.6e-06
  PI3K_P85_iSH2   19 lrevskqlqekskeydqlkeeynkiseeiqlkrqaleaFneaikmFeeqiklqekfskea...qehEieklqenleqlk 94  
                     lr   + l +   e +++k + ++++e++q k  ++ea +e  + F eqi+  e++ +e+   + +E+++l+++++ l+
     EEA21977.1 1177 LRMARERLAKADAEVERKKRQLEQMQEDLQNKNDTIEAGTELKTEFLEQIREAERVREECrgwSIKEVNSLKDSVQMLE 1255
                     7778888999999***********************************************6666999999999998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1507 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1543  (0.0860617); expected 358.6 (0.02)
Passed bias filter:                      496  (0.0276647); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 1.04u 0.29s 00:00:01.33 Elapsed: 00:00:00.46
# Mc/sec: 9864.66
//
Query:       EEA21978.1  [L=750]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-19   70.1   0.2    3.2e-19   69.0   0.2    1.6  1  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.0   0.2   1.8e-23   3.2e-19       2     200 ..     178     367 ..     177     438 .. 0.76

  Alignments for each domain:
  == domain 1  score: 69.0 bits;  conditional E-value: 1.8e-23
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailal.GalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsL 97 
                     +fs ++  fpi+h+ +f++    ++ ++ + ++ +  ++i+al + +f + +++   +++  e+   +++  +a+ +  +++s  ++++  +q+L
    EEA21978.1 178 RNYFSTINRIFPIIHEKTFMDMV-EWQYTQQKCTDVGRWASINALlALSFRYRDDRGPRPEKDAER-AWLYWKNAAAVY--TELSLRPNDILGIQAL 270
                   57********************9.999999999999988777765144444444444333333333.444444455555..5*************** PP

  Fungal_trans  98 lllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddlwe 194
                   l ++++    +   l+  ++  a++ a+ lgLhr+  + +       ++ e e+r+R+ww++F++D  i +k+Gr +l + ++ ++ LP +  +  +
    EEA21978.1 271 LVMAIFARVNGHLQLAIPLITAAMKSAQALGLHRRNLNPN------ISASELETRKRVWWCIFVMDQGIGIKTGRGYLQHPDDSDVDLPSENPKAFN 361
                   ***************************************9......*******************************87777777777777765555 PP

  Fungal_trans 195 sddase 200
                     ++ +
    EEA21978.1 362 DIQNGC 367
                   555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (750 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       594  (0.0331307); expected 358.6 (0.02)
Passed bias filter:                      486  (0.0271069); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.30s 00:00:00.95 Elapsed: 00:00:00.44
# Mc/sec: 5166.46
//
Query:       EEA21979.1  [L=767]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      4e-17   62.1   1.0    7.7e-17   61.2   1.0    1.4  1  Fungal_trans    Fungal specific transcription factor domain
    3.4e-06   27.1  11.6    6.5e-06   26.2  11.6    1.4  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.065   14.0   1.2       0.13   13.0   1.2    1.4  1  MRNIP           MRN-interacting protein
      0.077   12.9   0.1       0.18   11.7   0.1    1.7  1  Pox_A_type_inc  Viral A-type inclusion protein repeat


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.2   1.0   1.7e-20   7.7e-17       1     205 [.     238     440 ..     236     508 .. 0.81

  Alignments for each domain:
  == domain 1  score: 61.2 bits;  conditional E-value: 1.7e-20
  Fungal_trans   1 ldrffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltses......qefiafplraeili.....hedfss 86 
                   l++ff  ++  +pi++   f+ +++s  +s++   s++l+  +lal +++++    ++ + l+++       +  i    + ++++     +   + 
    EEA21979.1 238 LHLFFPSYNVYYPIIDLAEFMQHYQSLWTSPTSRRSSALVDIVLALSMQYADALMPRDYAALRNNIegivniDAAI----AGRKFYrrcqlLLTDEL 330
                   678999999999************9999999999***********************9888887657755554444....88888888888455566 PP

  Fungal_trans  87 pssslwilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinl 183
                   + +s+++lq+ ++  +y+++ s  +++  h+ +avr  + lgLh +p+ +       ++   ae r+Rlww+++ l++   l lGrp  l  sqi +
    EEA21979.1 331 EGPSITTLQCHFFSVIYLSNASFHNAAHSHLAMAVRTGTILGLHWHPPGKV------SDQQ-AEFRKRLWWTVYALEIKMTLELGRPLALTMSQIPC 420
                   66669***************************************9999987......7777.**************************778888888 PP

  Fungal_trans 184 pLPcddddlwesddaseetlve 205
                   p P  d+++++ ++  + ++  
    EEA21979.1 421 PPP--DRHQDDPYTHQGTNRFT 440
                   877..66667777666666666 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.2  11.6   1.4e-09   6.5e-06       1      33 [.      38      68 ..      38      73 .. 0.93

  Alignments for each domain:
  == domain 1  score: 26.2 bits;  conditional E-value: 1.4e-09
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfy 33
                +aCd Cr+ +vKCd + P C+nC++++ +C  +
  EEA21979.1 38 RACDWCRSLRVKCDNRYP-CRNCQTKGRTCN-I 68
                69****************.***********8.5 PP

>> MRNIP  MRN-interacting protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   1.2   2.8e-05      0.13       7      80 ..      40     113 ..      38     159 .. 0.74

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 2.8e-05
       MRNIP   7 CetfqvkqvkKskkwkCkvCnekqslkkvygsgsgkdcrqlVqklnlkkgekeeeedeelkekkqeeeekeese 80 
                 C   +   vk+ +++ C+ C++k     + g ++++ c   + +  +++  +++ e++ + +k++ ++++++++
  EEA21979.1  40 CDWCRSLRVKCDNRYPCRNCQTKGRTCNIRGANAAQTCNAAISRIAVLQDRIRDLEQQVEIAKAKIQDDDDDDD 113
                 55555667899*****************************************9998833333333333333322 PP

>> Pox_A_type_inc  Viral A-type inclusion protein repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.1   4.1e-05      0.18       6      20 ..      87     101 ..      84     103 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 4.1e-05
  Pox_A_type_inc   6 lRsRIsDLErqLseC 20 
                     l++RI+DLE+q +++
      EEA21979.1  87 LQDRIRDLEQQVEIA 101
                     89********97765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (767 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       774  (0.0431703); expected 358.6 (0.02)
Passed bias filter:                      592  (0.0330191); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.74u 0.31s 00:00:01.05 Elapsed: 00:00:00.49
# Mc/sec: 4692.81
//
Query:       EEA21980.1  [L=330]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.2e-22   77.9   0.1    1.9e-21   75.8   0.1    2.1  2  DUF1932        Domain of unknown function (DUF1932)
    0.00097   19.7   0.0     0.0023   18.5   0.0    1.6  1  F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
     0.0043   17.2   0.0      0.011   15.9   0.0    1.8  1  NAD_binding_2  NAD binding domain of 6-phosphogluconate dehyd
  ------ inclusion threshold ------
       0.03   13.7   0.0      0.069   12.5   0.0    1.5  1  2-Hacid_dh_C   D-isomer specific 2-hydroxyacid dehydrogenase,
        0.1   12.4   0.0       0.18   11.7   0.0    1.4  1  3HCDH_N        3-hydroxyacyl-CoA dehydrogenase, NAD binding d


Domain annotation for each model (and alignments):
>> DUF1932  Domain of unknown function (DUF1932)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       1.1     4e+03      43      56 ..     119     132 ..     118     137 .. 0.84
   2 !   75.8   0.1   5.3e-25   1.9e-21       1      70 []     222     295 ..     222     295 .. 0.98

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 1.1
                 HHHHHHHHHCTTS- CS
     DUF1932  43 Meeiaetlaeegle 56 
                 M+ei   +a++ ++
  EEA21980.1 119 MREIDSLFASLSGP 132
                 9***9999998765 PP

  == domain 2  score: 75.8 bits;  conditional E-value: 5.3e-25
                 HHHTT-HHHHHHHHHHHSSTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTT....S--HHHHHHHHHHHHC CS
     DUF1932   1 AhrlGVldelldeleeslpallaraergltgmppkAyRwveEMeeiaetlaeeg....lepqmfraiaevyrlv 70 
                 A++ GVl +ll++l+e+ p+++a a++g++ m+pkAyRwveEM +i+e +++eg    l + +++ +aevyr+v
  EEA21980.1 222 AQSEGVLSDLLQHLNEYSPKTAALATGGIVAMAPKAYRWVEEMHAIGEAFDSEGhwggLGSAVYDSFAEVYRQV 295
                 8999******************************************************99************97 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.0   6.4e-07    0.0023       2      81 ..       5      82 ..       4      92 .. 0.83

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 6.4e-07
                   EEEETTSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC-EEECECHHHHHHH-SEEEE-S-HHHHHHHHHHC CS
  F420_oxidored  2 igiiGaGnmgealasgllaagaqpheivvansrnpekaeelaeelgvkvtavdneeaaeeadvvvlavkpedveevlsel 81
                   +gi+  G+mg ++a+ l a+ ++   +  a++rn        +++++++ + + +e++ ++d ++  v+p+d  ++++ +
     EEA21980.1  5 VGILSIGDMGMGIARLLKANSYRVLTVA-AGRRNVYNTLDRIQAASIEALP-TDQELVIQSDYILSIVPPRDSLATARRI 82
                   8**************7777775777777.66888877777778889*****.88888888***********999888887 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   3.1e-06     0.011       2      69 ..       5      76 ..       4     159 .. 0.82

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 3.1e-06
                   EEEE--SHHHHHHHHHHHHTT-EEEEE-SSHHHHHHHHHTT....EEE-SSHHHHHHHCSEEEE-SSSHHHH CS
  NAD_binding_2  2 igfiGlGvMGsnmalnllkagykvavynrtkekveelvaeg....akaaesieelvasldvvitmvkagkav 69
                   +g++ +G MG+ +a+ l+++ y+v  +   + +v + +++     ++a+ + +elv + d ++ +v+  +  
     EEA21980.1  5 VGILSIGDMGMGIARLLKANSYRVLTVAAGRRNVYNTLDRIqaasIEALPTDQELVIQSDYILSIVPPRDSL 76
                   788999******************999877766655555433445*********************976544 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   1.9e-05     0.069      38     103 ..       4      74 ..       2      90 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.9e-05
                   EEEEES-SHHHHHHHHHHHHTT-EEEEESSSHHHHH....CHHHHTCEEC.SHHHHHHH-SEEEE-S--ST CS
  2-Hacid_dh_C  38 tvGiiGlGrIGqavakrlkafgmkviaydrskkkee....eeeelgvelv.sleellaesDivslhlpltp 103
                    vGi+ +G++G  +a++lka   +v+ +   +++      + ++  +e   + +el+ +sD++   +p  +
    EEA21980.1   4 SVGILSIGDMGMGIARLLKANSYRVLTVAAGRRNVYntldRIQAASIEALpTDQELVIQSDYILSIVPPRD 74 
                   69***********************9998877754444455555556555366799999999999999765 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0     5e-05      0.18       2      86 ..       5      86 ..       4     104 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 5e-05
                EEEE--SCCHHHHHHHHHHTT-EEEEE-S-HHHHHHHHHHHHH.HHHCCTTTTSS-HHHHCCCHHCEEEES-HHHHHC-SEEEE-S CS
     3HCDH_N  2 vaviGaGtmGagiaavfasagleVvlvdiseealekalekiek.sleklvekgklkeeeveaalarisfttdleeavdadlviEav 86
                v+++  G mG gia ++ ++ ++V  v   ++ + + l++i++ s+e l  +++l   + + +l+ + + ++l++   a  ++Eav
  EEA21980.1  5 VGILSIGDMGMGIARLLKANSYRVLTVAAGRRNVYNTLDRIQAaSIEALPTDQELV-IQSDYILSIVPPRDSLAT---ARRIFEAV 86
                899999****************************9999999984555554444443.334444444444444443...35555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (330 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       435  (0.0242624); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.47
# Mc/sec: 2117.36
//
Query:       EEA21981.1  [L=335]
Description: bZIP transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.8e-10   40.8   9.4    1.8e-10   40.8   9.4    2.2  2  bZIP_2    Basic region leucine zipper
  ------ inclusion threshold ------
      0.018   13.3  12.9      0.024   12.9  12.9    1.0  1  FPP       Filament-like plant protein, long coiled-coil
        0.4    9.6   3.3       0.54    9.2   3.3    1.1  1  SidC_N    SidC N-terminal domain
        4.4    7.5  16.8        3.8    7.7  12.0    2.5  2  bZIP_1    bZIP transcription factor


Domain annotation for each model (and alignments):
>> bZIP_2  Basic region leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.8   9.4   3.9e-14   1.8e-10       5      54 .]     199     248 ..     196     248 .. 0.97
   2 ?    2.1   0.6     0.048   2.1e+02      37      52 ..     256     271 ..     253     272 .. 0.90

  Alignments for each domain:
  == domain 1  score: 40.8 bits;  conditional E-value: 3.9e-14
                 XXXXXXXXXXXXXX-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_2   5 yrerRrkNreAarrsRekkkakeeeleervkeLeeeNaqLrqkveqLeke 54 
                 ++++Rr+N++A++r+R kkk++e+ le+ v e +e +++L+ +v qLe e
  EEA21981.1 199 EEDKRRRNTAASARFRVKKKQREQALERAVHEATEVKSALETRVTQLEME 248
                 579*********************************************87 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.048
                 HHHHHHHHHHHHHHHH CS
      bZIP_2  37 LeeeNaqLrqkveqLe 52 
                 L+e+N+ L+ ++++L+
  EEA21981.1 256 LTEKNENLLSRLAALQ 271
                 89***********996 PP

>> FPP  Filament-like plant protein, long coiled-coil
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9  12.9   5.3e-06     0.024     232     345 ..     200     312 ..     188     314 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 5.3e-06
         FPP 232 esrlrrspaksssa..llskveefsedsleklqkenefLterLlameeEtkmLKEaLakrnsELqaSrnmcAktaskLsqlEaqleelskqksqvslel 328
                 e ++rr+ a s++   +  + e+ +e ++++     + L +r+ ++e E++ LK+ L+ +n+ L  Sr + A   s L++lE + +++s   s++s+  
  EEA21981.1 200 EDKRRRNTAASARFrvKKKQREQALERAVHEATEVKSALETRVTQLEMENRWLKNLLTEKNENL-LSR-LAALQPSDLEKLELHQQDSSGV-SSTSSTA 295
                 4444554444444444445567888899999999999************************999.577.567889*********9877776.5455555 PP

         FPP 329 vssqnpasnelslaSms 345
                 + +q+++s++    S+s
  EEA21981.1 296 TVTQHTTSKKADANSTS 312
                 55777778888888877 PP

>> SidC_N  SidC N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   3.3   0.00012      0.54     144     245 ..     199     307 ..     195     313 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00012
                 S--S-----..S-SEE----B-GGGSSS-B...HHHHHHHS-TT--EE-----HHHHHHHH...HHTTS-TT--S-STTHHHHHHHHHHH.HHTT-GGG CS
      SidC_N 144 eqDsflrseavnPvFsvkrkssaeeakesl...srLqeallkaytplviekkdlkeklvek...vlsklddespvdfekirkllkeevka.llkvevdf 235
                 e+D+  r +a++  F+vk+k+ ++  ++++   ++ ++al ++ t+l +e++ lk+ l+ek    ls+l++ +p d ek++  +++ +     +++ ++
  EEA21981.1 199 EEDKRRRNTAASARFRVKKKQREQALERAVheaTEVKSALETRVTQLEMENRWLKNLLTEKnenLLSRLAALQPSDLEKLELHQQDSSGVsSTSSTATV 297
                 79999****************99999777766679***************9988887775422288999999999999988777666544135556677 PP

                 GG--SSBB-- CS
      SidC_N 236 sktkeskpin 245
                 +++++sk+ +
  EEA21981.1 298 TQHTTSKKAD 307
                 7777776655 PP

>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7  12.0   0.00085       3.8       8      61 ..     201     254 ..     196     257 .. 0.92
   2 ?    6.2   2.6    0.0024        11      29      57 ..     236     261 ..     231     279 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00085
                 XXX--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1   8 krkqkNReaArrsRqRKqaeieeLerrvkaLekeNksLkseleelkkevekLks 61 
                  ++ +N  a +r+R +K+++ ++Ler v + ++  ++L  ++ +l+ e+  Lk+
  EEA21981.1 201 DKRRRNTAASARFRVKKKQREQALERAVHEATEVKSALETRVTQLEMENRWLKN 254
                 57889*****************************************99998886 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.0024
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  29 eeLerrvkaLekeNksLkseleelkkeve 57 
                 ++Le+rv +Le eN  Lk+ l e +   e
  EEA21981.1 236 SALETRVTQLEMENRWLKNLLTEKN---E 261
                 57*************9987554433...3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (335 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1796  (0.100173); expected 358.6 (0.02)
Passed bias filter:                      684  (0.0381505); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.60u 0.31s 00:00:00.90 Elapsed: 00:00:00.46
# Mc/sec: 2194.92
//
Query:       EEA21982.1  [L=351]
Description: cell wall integrity signaling protein Lsp1/Pil1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   5.1e-127  422.9   0.1   6.4e-127  422.5   0.1    1.1  1  Pil1      Eisosome component PIL1


Domain annotation for each model (and alignments):
>> Pil1  Eisosome component PIL1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  422.5   0.1  3.6e-131  6.4e-127       1     263 [.       1     263 [.       1     265 [. 1.00

  Alignments for each domain:
  == domain 1  score: 422.5 bits;  conditional E-value: 3.6e-131
        Pil1   1 mnraysirsskastasesqteaspksstkskrlfslkslrsslrkqaaasfsPelarrLakLikseknlvraheaaarerksiakqlseWGedtdddvs 99 
                 m+r+ys+r+s+a+tas+ +++++p+sstks+rlf+ +++++++rk+aa++f+P+la++L++L+k+ekn++r++e ++rer+++a+qls WGe  dddvs
  EEA21982.1   1 MHRTYSMRQSRAPTASQIENPPPPPSSTKSGRLFGRNNFGHAFRKNAAGAFGPDLAKKLSQLVKMEKNVMRSMELVGRERMEVAQQLSIWGEAGDDDVS 99 
                 8************************************************************************************************** PP

        Pil1 100 DvsDklgvllselgeledayadrldqsRatlKsirniEasvqpsRdkkekladeiaklkakepqserlvvlEqeLvraeaeslvaeaqlsnitReklke 198
                 Dv+Dklgvl++e+geled+++dr+dq+R+t+KsirniEasvqpsRd+k+k++deiaklk+k+p+s+r+vvlEqeLvraeaeslvaeaqlsnitReklk+
  EEA21982.1 100 DVTDKLGVLIYEIGELEDQFVDRYDQYRLTIKSIRNIEASVQPSRDRKQKITDEIAKLKYKDPNSPRIVVLEQELVRAEAESLVAEAQLSNITREKLKA 198
                 *************************************************************************************************** PP

        Pil1 199 aytaefdaliEraeKlallarygkrLlellddspvtpGetrpaYdgaeatrqiladaedaLrewr 263
                 a+t++fdal+E++eK+a++a+ygk+Llel+dd+pvtpGetr+aYdg++a++ i++d+edaL++w 
  EEA21982.1 199 AFTYQFDALREHCEKIAIIAGYGKHLLELIDDTPVTPGETRQAYDGYDASKAIIQDCEDALTNWV 263
                 ****************************************************************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (351 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       674  (0.0375927); expected 358.6 (0.02)
Passed bias filter:                      435  (0.0242624); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 2415.16
//
Query:       EEA21983.1  [L=1127]
Description: DNA excision repair protein Rad2 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.4e-34  117.8   0.0    6.8e-34  116.4   0.0    1.8  1  XPG_N           XPG N-terminal domain
    1.3e-25   89.6   0.1    2.2e-24   85.6   0.0    2.6  2  XPG_I           XPG I-region
    3.8e-05   23.3   0.3    3.8e-05   23.3   0.3    4.0  3  UIM             Ubiquitin interaction motif
    0.00011   22.7   0.0    0.00037   21.1   0.0    1.8  1  5_3_exonuc      5'-3' exonuclease, C-terminal SAM fold
  ------ inclusion threshold ------
      0.016   15.5   0.6      0.035   14.4   0.0    1.8  2  Transposase_20  Transposase IS116/IS110/IS902 family


Domain annotation for each model (and alignments):
>> XPG_N  XPG N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.4   0.0   1.9e-37   6.8e-34       1      99 [.       1      96 [.       1      98 [. 0.99

  Alignments for each domain:
  == domain 1  score: 116.4 bits;  conditional E-value: 1.9e-37
                X--TTHHHHHHHH-GEEEEEGGGGTTEEEEEEHHHHHHHHHHHSE.ETTEE-BS-HHHHHHHHHHHHHHHTTEEEEEEE--S--GGGHHHHHHHHHHHH CS
       XPG_N  1 MGikgLlkllkevaairsvsiealegkklaiDaslwlyrfliavreqlgnalentshlmglfsrllrlldfgikPifVFdgkapdlkkeelekrserrq 99
                MG+ gL+ ++++ a  r+v++e+l+ k+la+Das+w+y+fl+avr+++gnal+n  h++g+f+r+++ll+fgikP+fVFdg+ap lk+++++ r++rr+
  EEA21983.1  1 MGVTGLWTVVQPCA--RPVKLETLNRKRLAVDASIWIYQFLKAVRDKEGNALRN-AHVVGFFRRICKLLFFGIKPVFVFDGGAPILKRQTIAARKKRRD 96
                **************..**************************************.******************************************97 PP

>> XPG_I  XPG I-region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0      0.18   6.4e+02      33      62 ..     407     437 ..     402     459 .. 0.68
   2 !   85.6   0.0   6.2e-28   2.2e-24       1      94 []     835     919 ..     835     919 .. 0.95

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.18
                 SSSHHHHTT-SEEEESTT..ECECTT..EEE CS
       XPG_I  33 eDsDlllFGapkvlrnls.kkkskkkkekek 62 
                 eD D+l F ap    +l+ ++++++ ++  +
  EEA21983.1 407 EDEDALFFSAPGDTDDLFgDSEDEDLQKAIA 437
                 8**********99999995444444433333 PP

  == domain 2  score: 85.6 bits;  conditional E-value: 6.2e-28
                 HHHT--EEE-SS-HHHHHHHHHHTTSSSEEE-SSSHHHHTT-SEEEESTT.ECECTT..EEECEEEEEEHHHHHHHHT--HHHHHHHHHHHCET CS
       XPG_I   1 klmgipyvvApgEAEAqcayLqkkglvdaviseDsDlllFGapkvlrnlskkkskkkkekekkkvevidlekvlkelgltreqlidlaillgcD 94 
                 +l+g+py++Ap+EAEAqca+L++ glvd+++++DsD++lFG++++++n++  ++        k ve++  ++++ke+ l+r +li++a llg+D
  EEA21983.1 835 RLFGLPYITAPMEAEAQCAELVSLGLVDGIVTDDSDTFLFGGTRIYKNMF--NQS-------KFVECFLSNDLEKEYALDRVKLIQFAHLLGSD 919
                 689**********************************************9..433.......47****************************99 PP

>> UIM  Ubiquitin interaction motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.3   0.3   1.1e-08   3.8e-05       1      16 [.     427     442 ..     427     443 .. 0.92
   2 ?   -0.4   0.9      0.38   1.4e+03       1      15 [.     474     488 ..     474     490 .. 0.83
   3 ?    0.2   0.7      0.26   9.3e+02       1       9 [.     768     776 ..     768     776 .. 0.93

  Alignments for each domain:
  == domain 1  score: 23.3 bits;  conditional E-value: 1.1e-08
         UIM   1 dEdedLqrAlalSlqE 16 
                 +EdedLq+A+a+Sl+ 
  EEA21983.1 427 SEDEDLQKAIAMSLEP 442
                 7*************95 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.38
         UIM   1 dEdedLqrAlalSlq 15 
                 d+d d+++Ala S q
  EEA21983.1 474 DDDMDFAAALARSKQ 488
                 68889******8887 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.26
         UIM   1 dEdedLqrA 9  
                 +Ed +Lq+A
  EEA21983.1 768 EEDLMLQLA 776
                 7******99 PP

>> 5_3_exonuc  5'-3' exonuclease, C-terminal SAM fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.1   0.0     1e-07   0.00037       7      64 ..     910     974 ..     907     986 .. 0.69

  Alignments for each domain:
  == domain 1  score: 21.1 bits;  conditional E-value: 1e-07
  5_3_exonuc   7 idlkaLvGDssDnipGvpgiGektAakLlkeygsleeilenldelke.........kklkekLeenk 64 
                 i+++ L G  sD  +G+pg+G+ tA ++++e+++lee  +   +++          ++ ++k+++ +
  EEA21983.1 910 IQFAHLLG--SDYTEGIPGVGPVTALEIITEFNNLEEFRDWWMQVQMgveipndphQQFRKKFKKMA 974
                 55666666..8999***********************998554332222223233345556655555 PP

>> Transposase_20  Transposase IS116/IS110/IS902 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   9.8e-06     0.035       6      30 ..     923     947 ..     919     949 .. 0.92
   2 ?   -5.2   1.1         5   1.8e+04      45      57 ..    1110    1123 ..    1109    1125 .. 0.70

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 9.8e-06
  Transposase_20   6 sipGiGpvtaaallaeigdlrrfks 30 
                      ipG+Gpvta++++ e ++l++f++
      EEA21983.1 923 GIPGVGPVTALEIITEFNNLEEFRD 947
                     79*********************97 PP

  == domain 2  score: -5.2 bits;  conditional E-value: 5
  Transposase_20   45 nqSGkkkr.rgris 57  
                      ++SG++++ r+r s
      EEA21983.1 1110 EDSGSTRKkRKRKS 1123
                      68999999666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1127 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       990  (0.0552178); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.83u 0.30s 00:00:01.12 Elapsed: 00:00:00.49
# Mc/sec: 6976.89
//
Query:       EEA21984.1  [L=412]
Description: hypothetical protein PMAA_057670 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
  ------ inclusion threshold ------
      0.077   13.9  12.9        0.4   11.6   0.2    4.1  3  zf-C2H2_4   C2H2-type zinc finger
        1.9    8.5  14.5       0.29   11.1   4.3    2.3  2  DUF1151     Protein of unknown function (DUF1151)


Domain annotation for each model (and alignments):
>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   1.6   0.00071       6.4       1      24 []      59      84 ..      59      84 .. 0.80
   2 ?   -0.7   0.4      0.42   3.8e+03       2       9 ..      91      98 ..      90     119 .. 0.77
   3 ?   11.6   0.2   4.5e-05       0.4       1      23 [.     146     169 ..     146     170 .. 0.96

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.00071
   zf-C2H2_4  1 fkCpi..CgksFsskkaLlrHlkthH 24
                ++C +  C++sF  ++ +  H++t H
  EEA21984.1 59 YICIHplCNQSFEYYHLWVEHVLTSH 84
                6777777*****66666788***998 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.42
   zf-C2H2_4  2 kCpiCgks 9 
                +C +C++ 
  EEA21984.1 91 YCLYCNAE 98
                69999765 PP

  == domain 3  score: 11.6 bits;  conditional E-value: 4.5e-05
   zf-C2H2_4   1 fkCpiC.gksFsskkaLlrHlkth 23 
                 f+C iC +++++++ ++  H+++h
  EEA21984.1 146 FPCGICrRTNWKTWFEFAAHMARH 169
                 89*********************9 PP

>> DUF1151  Protein of unknown function (DUF1151)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   4.3   3.2e-05      0.29      55     112 ..     192     245 ..     186     247 .. 0.80
   2 ?    2.7   2.5     0.013   1.2e+02      47      91 ..     265     308 ..     258     322 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 3.2e-05
     DUF1151  55 eqvlkqkkeeeeakkkkseLeqelekraqrleelekeeekqkeeqekapefvkvkekL 112
                 ++ l++k+ ++  k+   +Le  l++r+++ +e e+e+       e+ pe+v+v  +L
  EEA21984.1 192 RKQLHKKRRQDAPKENVDNLELSLNRRQHKPDEDEEESDLS----EEDPEYVRVDREL 245
                 4568888999999999999***********99655555554....456******9887 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.013
     DUF1151  47 rvlekrkeeqvlkqkkeeeeakkkkseLeqelekraqrleeleke 91 
                 +v ek ke   + q ++ee  ++++ ++e + ++r++r ++ ++ 
  EEA21984.1 265 KVHEKVKE-SKQDQDEQEEPTSSPHVKFEDKSRDRNHRKHASHNP 308
                 78888886.666777777777788888888888888777655544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (412 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1459  (0.0813765); expected 358.6 (0.02)
Passed bias filter:                      559  (0.0311785); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 2839.84
//
Query:       EEA21985.1  [L=1154]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1154 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1045  (0.0582855); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.84u 0.32s 00:00:01.15 Elapsed: 00:00:00.49
# Mc/sec: 7151.01
//
Query:       EEA21986.1  [L=2472]
Description: 1-phosphatidylinositol-3-phosphate 5-kinase (Fab1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.2e-34  119.8   0.3    1.2e-25   90.3   0.4    2.6  2  PIP5K       Phosphatidylinositol-4-phosphate 5-Kinase
    2.3e-28   99.1   0.0    4.1e-28   98.3   0.0    1.3  1  Cpn60_TCP1  TCP-1/cpn60 chaperonin family
      2e-15   56.7   4.0      2e-15   56.7   4.0    1.9  2  FYVE        FYVE zinc finger
     0.0066   16.3   2.3      0.021   14.7   2.3    1.8  1  C1_1        Phorbol esters/diacylglycerol binding domain (C1 


Domain annotation for each model (and alignments):
>> PIP5K  Phosphatidylinositol-4-phosphate 5-Kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.3   0.4   2.6e-29   1.2e-25      10     166 ..    2204    2368 ..    2196    2373 .. 0.81
   2 !   27.3   0.0   4.2e-10   1.9e-06     224     273 ..    2373    2425 ..    2367    2426 .. 0.90

  Alignments for each domain:
  == domain 1  score: 90.3 bits;  conditional E-value: 2.6e-29
                  ---SSS--EEEETTSSEEEEEE-HHHHHHHHHHHHHHHHHHTT-T....T--S--EEEEEEEE.E...TTEEE.....EEEEEE-SS-TTS--SEEE CS
       PIP5K   10 seGkSgsffylteDkkfiiKtitksevkflrkllpeYyehvkenp....nsLltrfyglhrvklk...ggkkv.....rfvVmenlfptdkeihery 94  
                  + Gk +s+f  t D++f++K++++ e + ++k+ p+Y++ ++e       s +++++g+++v +k   +          +++menlf+  +  ++ +
  EEA21986.1 2204 KGGKTKSLFLKTLDDRFVLKSLSQIETQAFLKFAPAYFQIMSEALfhelPSAIAKMFGFYQVIIKnpvT---GvefnwFLLLMENLFYDRVP-TRIF 2296
                  679**************************************964444459************7755552...14446699*******76666.9*** PP

                  EE-S--TT-S--HHHHTSSS-EEEHH...HHHHHST.EEE-HHHHHHHHHHHHHHHHHHHHTTB-S-EEEEEEEB CS
       PIP5K   95 DLKGstvgReakkkeeekkektlkDl...DliekkeklklgkekreelleqlekDvefLeslnimDYSLLlGihn 166 
                  DLKGs  +R+++++ e+++  +l D    D+i++ + l   +++++ l + + +D+ fL ++n+mDYSL+++i +
  EEA21986.1 2297 DLKGSMRNRKVQSTGERDE--VLLDEnmvDFIYE-TPLFTREHSKKLLSQSVWNDTLFLGRQNVMDYSLMIAIDE 2368
                  ***********96544333..4555402266666.3477788889999999*********************954 PP

  == domain 2  score: 27.3 bits;  conditional E-value: 4.2e-10
                  EEEEEE----B--------------...--------TTHHHHHHHHHHHHHHH CS
       PIP5K  224 yylgiIDiLqkynlkKklehalksl...kkdkksisavpPkeYaeRFlkfiek 273 
                  + +giID++ +y++ Kkle+++k        k+  +++ PkeY++RF + + +
  EEA21986.1 2373 LVVGIIDCIRTYTWDKKLESWIKDRgfaGGGKNRPTVTSPKEYKSRFRQAMAR 2425
                  789********************999997778889**************9986 PP

>> Cpn60_TCP1  TCP-1/cpn60 chaperonin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.3   0.0   9.1e-32   4.1e-28     141     362 ..     877    1101 ..     853    1111 .. 0.87

  Alignments for each domain:
  == domain 1  score: 98.3 bits;  conditional E-value: 9.1e-32
                  HHHHHHHHHH.HCHCCCS..EECSCCC.EECCCCEECECTTSEEESEEEESS--SSTTSSCEEECEEEEEESS-BS--HHCCHHHCCCCSCCHHHHH CS
  Cpn60_TCP1  141 elsklvvdAv.klieene..keldlgr.ikvvkieggsledselveGlvldkgvlspdmpkklenakvllldvsLeiektetkttvvlsdaeelekl 233 
                   l  ++++A   + ++ +   ++d+   +k++ki gg+  d++ v Glv+ k+++ ++mp+++ ++++l++++ +e+++         +    le +
  EEA21986.1  877 ALLPILLRATdDVDPDVQrgDDMDIRHyVKLKKIPGGRPGDTSYVSGLVFTKNLALKSMPRSIPQPRILIITFAIEYARH-------QQHFMSLEPV 966 
                  5556667777555555556656666666**************************************************99.......446678999* PP

                  HHHHHHHHHHHHHHHHHTTECEEEESS-B-HHHHHHHHHCT-EEE-S--HHHHHHHHHHHT--EBSCGGGGG..CGC-EEEEEE..EECCETT..CC CS
  Cpn60_TCP1  234 ekaeekqleellekiiksgvnvvvcqkgiddlalhflakngilalrrvkkkdlerlakatGatavssledlt..peelGtakkv..eeekigs..ek 324 
                   ++e+++le+l+ +i++++ n+++++k+++ lal++l+k++i ++ +vk + le ++++t +++++s+++l   p++ G+++++  ++  +g   ++
  EEA21986.1  967 IRQEREFLENLVCRIAALQPNLLLVEKSVSGLALELLEKSNIATAYNVKPSVLEAVSRCTQTRIITSMDKLVtiPTHTGHCDSFdlKTYVYGGrrKT 1063
                  ***********************************************************************966799******95555566655588 PP

                  EEEEECESSSSXEEEEEEESTCCCHHHHHHHHHHHHHH CS
  Cpn60_TCP1  325 ttiieevksgkiatillrgatdtvldeieraiedAlnv 362 
                  +++i++++++  +ti+lrga+ +vl  ++r  e  + v
  EEA21986.1 1064 YMYISGCAKELGCTIVLRGANGEVLSRVKRITEFMVYV 1101
                  999**************************987655555 PP

>> FYVE  FYVE zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.7   4.0   4.5e-19     2e-15       3      66 ..     475     536 ..     473     538 .. 0.94
   2 ?   -4.3   0.9         4   1.8e+04      28      33 ..    1414    1419 ..    1410    1422 .. 0.61

  Alignments for each domain:
  == domain 1  score: 56.7 bits;  conditional E-value: 4.5e-19
                 --...--SB-TTT--B--SSS--EE-TTT--EE-STTS-EEE.EEGGGTEEEEEEE-HHHHHHH CS
        FYVE   3 wkddsevkkCeiCakkFsllrrrhhCrlCGkvvCekCssklvallekeaeeksvrvCkeClael 66 
                 w++d+++k C  C ++F+++rr+hhCr+CG+++ +kC+s l  +     + +svrvCk C + +
  EEA21986.1 475 WMRDENAKDCFLCGEPFTTFRRKHHCRTCGQIFDSKCTSLLPGVY--FGQGSSVRVCKPCEDMI 536
                 9**************************************999777..99***********8765 PP

  == domain 2  score: -4.3 bits;  conditional E-value: 4
                  -TTT-- CS
        FYVE   28 CrlCGk 33  
                  C++CG+
  EEA21986.1 1414 CKICGN 1419
                  555554 PP

>> C1_1  Phorbol esters/diacylglycerol binding domain (C1 domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   2.3   4.6e-06     0.021       9      46 ..     479     515 ..     473     517 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 4.6e-06
                 SS--B-TTT-SB--SSSS-EEEETTT--EE-CCCCTTS CS
        C1_1   9 kqptfCkhCgeflwgkekqglkCswCkllvHkkChekv 46 
                 ++ + C  Cge++ + +++  +C++C+++++ kC +++
  EEA21986.1 479 ENAKDCFLCGEPF-TTFRRKHHCRTCGQIFDSKCTSLL 515
                 57789********.9999999*************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2472 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       962  (0.0536561); expected 358.6 (0.02)
Passed bias filter:                      486  (0.0271069); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.27u 0.31s 00:00:01.58 Elapsed: 00:00:00.50
# Mc/sec: 14762.21
//
Query:       EEA21987.1  [L=525]
Description: pyruvate kinase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   3.3e-176  585.3   3.9   4.4e-176  584.9   3.9    1.1  1  PK            Pyruvate kinase, barrel domain
    1.1e-37  128.8   0.0    5.2e-37  126.7   0.0    2.1  2  PK_C          Pyruvate kinase, alpha/beta domain
    4.8e-05   22.6   0.3    0.00016   20.9   0.1    1.9  2  HpcH_HpaI     HpcH/HpaI aldolase/citrate lyase family
     0.0094   15.0   0.1      0.083   11.9   0.0    2.1  2  IMPDH         IMP dehydrogenase / GMP reductase domain
  ------ inclusion threshold ------
       0.07   13.4   0.0       0.15   12.4   0.0    1.6  1  NTP_transf_2  Nucleotidyltransferase domain


Domain annotation for each model (and alignments):
>> PK  Pyruvate kinase, barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  584.9   3.9  1.2e-179  4.4e-176       2     347 ..      32     377 ..      31     378 .. 0.99

  Alignments for each domain:
  == domain 1  score: 584.9 bits;  conditional E-value: 1.2e-179
                 --SEEEEEESCCCTSHHHHHHHHHHTEEEEEEETTSS-HHHHHHHHHHHHHHHHTTTTS.-EEEEE---S-EBB--BTTCSSSEEE-TTSEEEEE-SCT CS
          PK   2 rrtkivctlGPasesvekleklieaGlnvvrlnfshGsheehqerienvreaekklgkk.vaillDtkGpeirtgllkdgkkdielkegdklkvsldek 99 
                 rrt+i+ct+GP+++svek+++l++aGlnvvr+nfshGs+e+hq++i+++reae+ ++++ vai+lDtkGpeirtg++ d +kd+ +++g+ ++v++d++
  EEA21987.1  32 RRTSIICTIGPKTNSVEKINELRKAGLNVVRMNFSHGSYEYHQSVIDHAREAERVQAGRpVAIALDTKGPEIRTGNTVD-DKDYPISAGTVFNVTTDDQ 129
                 9*****************************************************999988*******************.88***************** PP

                 CTTTBBTTEEEBS-TTHHHHS-TTEEEEETTTTEEEEEEEEETTEEEEEEESS-EEE-SS-BEE-TTS---S-SS-HHHHHHHHHHHHCT-SEEEETTE CS
          PK 100 lkeegdeelialdyknivkdvevGktilvdDGllslkvlevdeekeleveventgvlgskkgvnlpgtkvdlpalsekDkadlrfgvkqgvdliaasfv 198
                 +++++d++++++dykni k++e+Gk i+vdDG+lslkvlev ++k+++v++ n+g+++s+kgvnlpgt+vdlpalsekDk+dlrfgvk+ vd+++asf+
  EEA21987.1 130 YATASDNKNMYVDYKNISKVIEPGKLIYVDDGILSLKVLEVVDDKTVRVQCLNNGNISSRKGVNLPGTDVDLPALSEKDKNDLRFGVKNRVDMVFASFI 228
                 *************************************************************************************************** PP

                 -SHHHHHHHHHHHTCCCTTSEEEEEE-SCHHHHTHHHHHHHSSEEEEEHHHHHHHSTCCCHHHHHHHHHHHHHHHT--EEEESSTTGGGGTSSS--HHH CS
          PK 199 rkasDvkevrevleeegkeikiiakienqegvenldeileasDgimvarGDlGieipaekvllvqkklikkcnlagkpvitatqmlesmiknPrptrae 297
                 r+++D+ke+r+vl+eegkei+iiakienq+gv+n+deile++DgimvarGDlGieipa+kv+++qk++i+kcnl+gkpvi+atqmlesm++nPrptrae
  EEA21987.1 229 RRGEDIKEIRKVLGEEGKEIQIIAKIENQQGVNNFDEILEETDGIMVARGDLGIEIPAPKVFIAQKMMIAKCNLKGKPVICATQMLESMTYNPRPTRAE 327
                 *************************************************************************************************** PP

                 HHHHHHHHHHT-SEEEESHHHHTSS-HHHHHHHHHHHHHHHHHTS-HHHH CS
          PK 298 vsDvanavlDGtDavmLsgetakGkyPveavkamaevaleaekalkelkl 347
                 vsDvanavlDG+D+vmLsgetakG+yP eav++m+e++l ae a+++ ++
  EEA21987.1 328 VSDVANAVLDGADCVMLSGETAKGNYPKEAVTMMSETCLLAEVAVPHFSI 377
                 *********************************************99876 PP

>> PK_C  Pyruvate kinase, alpha/beta domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0      0.89   3.2e+03      72     100 ..      67      95 ..      30     109 .. 0.56
   2 !  126.7   0.0   1.4e-40   5.2e-37       1     117 []     393     515 ..     393     515 .. 0.98

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.89
                 ..TTSHHHHHHHHHHHTTSS-STSEEEEE CS
        PK_C  72 estdellreavkvakeaglvkkgdevvvt 100
                 +   e  + ++++a ea+ v++g  v + 
  EEA21987.1  67 HGSYEYHQSVIDHAREAERVQAGRPVAIA 95 
                 33444455667788888888887776554 PP

  == domain 2  score: 126.7 bits;  conditional E-value: 1.4e-40
                 HHHHHHHHHHHHHHT-SEEEEE-SSSHHHHHHHHT-TSSEEEEEESHHHHHHHHHHCTTEEHHH.HHHHH..........TTSHHHHHHHHHHHTTSS- CS
        PK_C   1 eaiakaaveaaeelgakaIvvltesGetArliskyrpkvpiiavtpneltarqlalyrGvypvlvekakt.......aestdellreavkvakeaglvk 92 
                 eaia++av+a+ el+a aI+vlt+sG+tArl++kyrp +pii++t+ne ++r ++lyrGvyp++++++k        +e++d +l+++++  ++ g+++
  EEA21987.1 393 EAIAMSAVSASLELNAGAILVLTTSGKTARLLAKYRPVCPIIMITRNEAASRYSHLYRGVYPFYFPESKPdfnvkiwQEDVDRRLKWGIHNGIKLGVIQ 491
                 89***************************************************************98777***************************** PP

                 STSEEEEEE-SSSS..SS--EEEEE CS
        PK_C  93 kgdevvvtaGtpkgesgttNtlrVv 117
                 kg +vv+++G++ g  g+tNt+rVv
  EEA21987.1 492 KGASVVCVQGWRGG-MGHTNTIRVV 515
                 ************99.*********7 PP

>> HpcH_HpaI  HpcH/HpaI aldolase/citrate lyase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.1   4.5e-08   0.00016      77     155 ..     211     281 ..     202     308 .. 0.73
   2 ?   -1.7   0.0      0.36   1.3e+03      15      33 ..     332     350 ..     324     361 .. 0.80

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 4.5e-08
                 HGG.HHHTTSSEEEESS--SHHHHHHHHHHTSHTTTS---HCCC-EEEEEE-SHHHHHTHHHHH.TSTTEEEEEE-HHHHH CS
   HpcH_HpaI  77 dle.vldlgaqvvlvPkvetaeealevvsalrepekgirganketrllaqiEsaegvknaeeIa.avegldgvflGaeDls 155
                 dl+  ++  ++ v   ++   e+++e+ ++l e         ke++++a iE ++gv+n +eI+ ++   dg++++  Dl 
  EEA21987.1 211 DLRfGVKNRVDMVFASFIRRGEDIKEIRKVLGEEG-------KEIQIIAKIENQQGVNNFDEILeET---DGIMVARGDLG 281
                 55555666666666666666677776666666665.......99*******************8555...55555566665 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.36
                 HHHCTC--SEEEEESSTSS CS
   HpcH_HpaI  15 ekaaiagaDsvliDlEdav 33 
                  +a + gaD v++ +E a 
  EEA21987.1 332 ANAVLDGADCVMLSGETAK 350
                 567788999***9999875 PP

>> IMPDH  IMP dehydrogenase / GMP reductase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.9   0.0   2.3e-05     0.083      90     143 ..      31      84 ..      20      94 .. 0.87
   2 ?    0.4   0.1     0.072   2.6e+02     219     237 ..     328     346 ..     325     361 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 2.3e-05
                 TSXB-EEEEE-SSTTHHHHHHHHHHTT-SEEEEE-STSSSHHHHHHHHHHHHHT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       IMPDH  90 kgrllvgaavgvkedalervkalveagvdvlvvdsahghsekvleavkeikkkv 143
                  +r  +  ++g k+++ e++++l +ag++v+ ++ +hg  e+  +++++ +++ 
  EEA21987.1  31 YRRTSIICTIGPKTNSVEKINELRKAGLNVVRMNFSHGSYEYHQSVIDHAREAE 84 
                 567778889*********************************999999988765 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.072
                 HHHHHHHHHTT-SEEEESC CS
                 xxxxxxxxxxxxxxxxxxx RF
       IMPDH 219 sgdivkAlaaGadavmlGs 237
                   d++ A+  Gad+vml  
  EEA21987.1 328 VSDVANAVLDGADCVMLSG 346
                 5799************954 PP

>> NTP_transf_2  Nucleotidyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   4.2e-05      0.15      22      74 ..     187     251 ..     187     289 .. 0.71

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 4.2e-05
                   HHHCTTSCTTSSEEEEEEESTTCHHH.............HHHEHHHHHHHHCCCEEECTTEEEEEE CS
  NTP_transf_2  22 SyarGtalkgSDiDllvvlpeevsre.............kkeegleklaeiikfleellglevdlv 74 
                   S+++G +l+g D+Dl  ++++++++                 ++ e+++ei+k+l e  g e+ ++
    EEA21987.1 187 SSRKGVNLPGTDVDLPALSEKDKNDLrfgvknrvdmvfaSFIRRGEDIKEIRKVLGE-EGKEIQII 251
                   89********************66449999999997775222333333333333333.55555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (525 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       557  (0.031067); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3574.24
//
Query:       EEA21988.1  [L=491]
Description: F-box domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.9e-51  172.1   0.0    1.1e-50  171.2   0.0    1.5  1  DUF3506     Domain of unknown function (DUF3506)
    2.8e-10   39.9   1.8    5.7e-10   38.9   0.9    2.0  2  F-box-like  F-box-like
    2.9e-08   33.4   0.7    2.9e-08   33.4   0.7    1.8  2  F-box       F-box domain
     0.0027   18.2   0.0     0.0052   17.3   0.0    1.4  1  Elongin_A   RNA polymerase II transcription factor SIII (Elon


Domain annotation for each model (and alignments):
>> DUF3506  Domain of unknown function (DUF3506)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  171.2   0.0   2.5e-54   1.1e-50       3     139 .]     269     463 ..     267     463 .. 0.76

  Alignments for each domain:
  == domain 1  score: 171.2 bits;  conditional E-value: 2.5e-54
     DUF3506   3 stystldpelytptkekPfqgiyvgdysghgceflllkqkdk................................ddeaelekeede...seeeae.... 62 
                 + +stldp+lytptk+kPfqgi+vgdy+ h+cefll+ q+d                                 +       ++de   +eee+e    
  EEA21988.1 269 WIFSTLDPALYTPTKDKPFQGIWVGDYNFHKCEFLLFLQRDGgepapltnnarrhlramlggarifeetpydfiN-------DQDEavtAEEEEEevvl 360
                 6789************************************99777777766666666655555555444443331.......22222211111112233 PP

     DUF3506  63 .........krkee....................rgrleAiKLtGDpnvPrGevtFvaedlgeeGlvrvaeeeefkGarvvkskghiAeegFrndkfvd 132
                          +   +                    +grle+iKLtGDpn+PrGe++Fvaed+g++Gl+ v+++eef+G+rvvkskghiA e++++d++v+
  EEA21988.1 361 lngrfedafE---RasppdslasnevdeyngvrfQGRLEGIKLTGDPNIPRGEISFVAEDIGPKGLLGVSQDEEFRGVRVVKSKGHIAFEHYTDDQWVN 456
                 4444433330...034445555556667888889999************************************************************** PP

     DUF3506 133 sqLllis 139
                 +qL+lis
  EEA21988.1 457 TQLFLIS 463
                 *****97 PP

>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.9   0.9   1.3e-13   5.7e-10       2      46 ..       5      48 ..       4      50 .. 0.95
   2 ?   -2.3   0.0      0.96   4.3e+03      23      31 ..     173     182 ..     162     184 .. 0.78

  Alignments for each domain:
  == domain 1  score: 38.9 bits;  conditional E-value: 1.3e-13
  F-box-like  2 srLPdEiLlqIFsyLppsdLlrlalVCrrWrrvaldtplLWrrlv 46
                 +LPdE+L +++s Lp+ dL++++++Cr  +r  +d+  LW+rlv
  EEA21988.1  5 TDLPDELLHDVLSLLPAVDLVSISATCRTLYRQSRDE-KLWQRLV 48
                58*********************************99.*****97 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 0.96
  F-box-like  23 r.lalVCrrW 31 
                 +  a+VC+++
  EEA21988.1 173 NrTARVCSSF 182
                 43799**976 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.4   0.7   6.4e-12   2.9e-08       3      45 ..       4      46 ..       3      48 .. 0.95
   2 ?   -3.9   0.2       3.2   1.4e+04      25      33 ..     174     182 ..     172     182 .. 0.80

  Alignments for each domain:
  == domain 1  score: 33.4 bits;  conditional E-value: 6.4e-12
                HHHS-HHHHHHHHHTS-HHHHHHHCTT-HHHHHHHTTHHHHHH CS
       F-box  3 lsrLPsevlrhILerLplsdllalrrVSkgwrilidsdrlwck 45
                l +LP+e+l+++L+ Lp +dl++++ +++++++  ++ +lw +
  EEA21988.1  4 LTDLPDELLHDVLSLLPAVDLVSISATCRTLYRQSRDEKLWQR 46
                569**************************************75 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 3.2
                 HHCTT-HHH CS
       F-box  25 alrrVSkgw 33 
                 + +rV+ ++
  EEA21988.1 174 RTARVCSSF 182
                 678999876 PP

>> Elongin_A  RNA polymerase II transcription factor SIII (Elongin) subunit A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0   1.2e-06    0.0052       4      72 ..       4      70 ..       1      74 [. 0.86

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 1.2e-06
   Elongin_A  4 vGdvpyellrpiLekctpeqLreiEensphla..eetdelWkklikrdfpeeskekstepkepkswrelYe 72
                + d+p ell ++L   ++  L +i   +  l    ++++lW++l++ ++p++ ++  +      ++++lY 
  EEA21988.1  4 LTDLPDELLHDVLSLLPAVDLVSISATCRTLYrqSRDEKLWQRLVNANIPNKITKPGIF----HTFKDLYS 70
                5699***************************965569**************98877665....47777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (491 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       370  (0.020637); expected 358.6 (0.02)
Passed bias filter:                      346  (0.0192983); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 3268.38
//
Query:       EEA21989.1  [L=737]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
     0.0016   18.7   5.0     0.0016   18.7   5.0    4.5  3  Csm1_N           Csm1 N-terminal domain
  ------ inclusion threshold ------
      0.012   15.9   9.8      0.012   15.9   9.8    5.7  6  ATG16            Autophagy protein 16 (ATG16)
      0.013   15.5  12.8      0.013   15.5  12.8    4.8  4  TMF_DNA_bd       TATA element modulatory factor 1 DNA binding
      0.026   14.7   1.4      0.026   14.7   1.4    4.3  5  DUF948           Bacterial protein of unknown function (DUF94
       0.61   10.3   9.8       0.33   11.2   0.4    4.1  4  FAA_hydrolase_N  Fumarylacetoacetase N-terminal
        1.1    7.4  34.0       0.28    9.3  25.9    2.4  2  FPP              Filament-like plant protein, long coiled-coi
        2.7    7.6  25.8        0.2   11.3   9.4    3.2  3  BAR_3            BAR domain of APPL family
          3    6.6  40.8       0.61    8.9  16.8    3.7  4  Spc7             Spc7 kinetochore protein
        3.2    7.0  48.4       0.35   10.2   0.2    4.3  4  GAS              Growth-arrest specific micro-tubule binding
        5.5    7.5  17.3        1.4    9.4   0.7    4.4  4  NPV_P10          Nucleopolyhedrovirus P10 protein


Domain annotation for each model (and alignments):
>> Csm1_N  Csm1 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.1     0.088   1.6e+02      34      57 ..     172     195 ..     165     204 .. 0.76
   2 ?   -5.0   6.8        10   1.8e+04      37      37 ..     493     493 ..     450     525 .. 0.56
   3 !   18.7   5.0     9e-07    0.0016       5      69 ..     539     606 ..     536     607 .. 0.91

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.088
      Csm1_N  34 qkletkdqeiesLkeqlaeleekv 57 
                 ++l++   eiesL+++l + e+  
  EEA21989.1 172 KDLKKAAAEIESLQKKLGSYESAQ 195
                 456777889******999988765 PP

  == domain 2  score: -5.0 bits;  conditional E-value: 10
      Csm1_N  37 e 37 
                 e
  EEA21989.1 493 E 493
                 2 PP

  == domain 3  score: 18.7 bits;  conditional E-value: 9e-07
      Csm1_N   5 teYKes.VqerldsAdll..vsklvhENsvLsqkletkdqeiesLkeqlaeleekvkeleerrkkqeE 69 
                  e+K+s +++  + Adl+  v +l++EN  L  ++  +dq+i +L  ++a + +++++++ + +k eE
  EEA21989.1 539 EEFKKSlIEKEKELADLAkhVGNLIEENKKLVDRIVERDQKIGHLNTRIADVSTELQSTQADLAKTEE 606
                 68888845677899***8889****************************************9999988 PP

>> ATG16  Autophagy protein 16 (ATG16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   1.1       7.4   1.3e+04     115     120 ..      38      43 ..      10      69 .. 0.37
   2 ?    1.2   0.2       0.2   3.6e+02     116     145 ..     165     194 ..     144     212 .. 0.49
   3 ?    2.3   2.8     0.093   1.7e+02      35     140 ..     286     376 ..     267     384 .. 0.54
   4 ?    4.5  10.3      0.02        35      68     149 ..     463     541 ..     411     545 .. 0.68
   5 ?   15.9   9.8   6.5e-06     0.012     104     185 ..     538     619 ..     534     620 .. 0.94
   6 ?    2.3   0.2     0.097   1.7e+02       7      50 ..     620     662 ..     617     700 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 7.4
       ATG16 115 eeklke 120
                 ++ +++
  EEA21989.1  38 DAVTRQ 43 
                 111111 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.2
       ATG16 116 eklkedeerlaeleaeraaletklkdreee 145
                 ++  ++++ l+++ ae+++l++kl + e +
  EEA21989.1 165 NRFDSEKKDLKKAAAEIESLQKKLGSYESA 194
                 333344444444444444444444444433 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.093
       ATG16  35 eaenaklekaaasaks..sksskksakekeasasqsnskqsakiqsleqklaqlreelaelyksrgelaqrllelneelqkleeklkedeerlaeleae 131
                 ++e++             +++ k      ++s    ++ +++ ++ +++ ++q+   l++++++ ++l+q l+++++el +   +  + ++ la+++++
  EEA21989.1 286 RKEKQ----------DlfNEWRK---LNPLSS----TEPEAEATTPPADFMKQIVPRLEAALRTESDLTQVLKATQDELNQMGFSGPNIDAILAQMRDT 367
                 22222..........23322222...111111....222344555666677777777888888888888888888888877666666666666666665 PP

       ATG16 132 raaletklk 140
                  ++ +++lk
  EEA21989.1 368 FESAREELK 376
                 555555555 PP

  == domain 4  score: 4.5 bits;  conditional E-value: 0.02
       ATG16  68 snskqsakiqsleqklaqlreelaelyksrgelaqrllelneelqkleeklkedeerlaeleaeraaletklkdreeelrek 149
                 + ++ +  +++ e+ +a+l++ l++ yk ++++++ + el+++ q+ +  +k   +r+++le+++++++   + r ++++e 
  EEA21989.1 463 RLQEVERALKEKEDSIAKLNTALKKYYKDQETHENIISELEKQQQEEQHISK---RRIKDLEDSVNSITNIADYRSKTIEEF 541
                 4456677889999999999999999999999999999999988776665555...556666666666555555555555554 PP

  == domain 5  score: 15.9 bits;  conditional E-value: 6.5e-06
       ATG16 104 llelneelqkleeklkedeerlaeleaeraaletklkdreeelrekeklvqdlqDElsaLqlqlnqaEeklrklekENkeLv 185
                 + e +++l ++e++l   ++ + +l +e+++l +++ +r++++  +++ + d+  El++ q  l + Ee ++ l++ Nk+ v
  EEA21989.1 538 IEEFKKSLIEKEKELADLAKHVGNLIEENKKLVDRIVERDQKIGHLNTRIADVSTELQSTQADLAKTEELNKMLQAHNKQHV 619
                 6677889999********************************************************************9855 PP

  == domain 6  score: 2.3 bits;  conditional E-value: 0.097
       ATG16   7 reRdarqekafaeliqaynrLldrtsaleaenaklekaaasaks 50 
                 ++Rd+  e++f++ ++ + + +d  ++ e++++  ek    + s
  EEA21989.1 620 EARDRI-EALFQNSMSKFAKVFDIERKNEKRREITEKILIGTDS 662
                 79***9.***********************99998665444443 PP

>> TMF_DNA_bd  TATA element modulatory factor 1 DNA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.7     0.067   1.2e+02      39      60 ..     171     192 ..     164     197 .. 0.58
   2 ?   15.5  12.8   7.1e-06     0.013       2      66 ..     466     530 ..     465     537 .. 0.91
   3 ?    1.2  11.7      0.21   3.9e+02      16      63 ..     561     608 ..     536     619 .. 0.54
   4 ?    6.1   2.4    0.0061        11      13      50 ..     586     623 ..     575     637 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.067
  TMF_DNA_bd  39 rkknkelekeikelkkklekle 60 
                 +k++k++  ei++l+kkl ++e
  EEA21989.1 171 KKDLKKAAAEIESLQKKLGSYE 192
                 3445555555555555554444 PP

  == domain 2  score: 15.5 bits;  conditional E-value: 7.1e-06
  TMF_DNA_bd   2 slekklkeKDeqIaqLmeEGekLskkelklnntikkLrkknkelekeikelkkkleklekeleel 66 
                 ++e  lkeK++ Ia+L + ++k+ k +  ++n+i++L k+ +e     k+  k le+++ +++++
  EEA21989.1 466 EVERALKEKEDSIAKLNTALKKYYKDQETHENIISELEKQQQEEQHISKRRIKDLEDSVNSITNI 530
                 67889************************************999988888889999999988876 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.21
  TMF_DNA_bd  16 qLmeEGekLskkelklnntikkLrkknkelekeikelkkkleklekel 63 
                 +L eE +kL +  ++  ++i  L+  +++  +e+++++  l+k e+  
  EEA21989.1 561 NLIEENKKLVDRIVERDQKIGHLNTRIADVSTELQSTQADLAKTEELN 608
                 345555555555555555555555555555555555555555555555 PP

  == domain 4  score: 6.1 bits;  conditional E-value: 0.0061
  TMF_DNA_bd  13 qIaqLmeEGekLskkelklnntikkLrkknkelekeik 50 
                 +Ia + +E++  ++   k ++  k+L+++nk++ +  +
  EEA21989.1 586 RIADVSTELQSTQADLAKTEELNKMLQAHNKQHVEARD 623
                 799999*************************9987665 PP

>> DUF948  Bacterial protein of unknown function (DUF948)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0       7.8   1.4e+04      26      43 ..     172     189 ..     162     192 .. 0.70
   2 ?    0.6   0.0      0.38   6.8e+02      23      58 ..     335     373 ..     324     382 .. 0.78
   3 ?    0.2   0.2       0.5   8.9e+02      23      46 ..     466     489 ..     454     532 .. 0.52
   4 ?   14.7   1.4   1.5e-05     0.026      25      86 ..     535     596 ..     511     599 .. 0.93
   5 ?   -0.7   0.3      0.99   1.8e+03      23      57 ..     606     640 ..     602     656 .. 0.58

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 7.8
      DUF948  26 ktldeaaatieelekqvd 43 
                 k l++aaa ie+l+k+++
  EEA21989.1 172 KDLKKAAAEIESLQKKLG 189
                 556677777777777665 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.38
      DUF948  23 klkktldeaaatieele...kqvdpilkevedllakvne 58 
                  l+++l+++++ +++++    ++d+il +++d+ + ++e
  EEA21989.1 335 DLTQVLKATQDELNQMGfsgPNIDAILAQMRDTFESARE 373
                 567888888888888887778889999999888888776 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.5
      DUF948  23 klkktldeaaatieelekqvdpil 46 
                 ++++ l+e +++i++l+  ++++ 
  EEA21989.1 466 EVERALKEKEDSIAKLNTALKKYY 489
                 333333333333333333333332 PP

  == domain 4  score: 14.7 bits;  conditional E-value: 1.5e-05
      DUF948  25 kktldeaaatieelekqvdpilkevedllakvnelledvneklekvdplteavadlgesvse 86 
                 +kt++e+++++ e ek++  + k v +l+++ ++l++ + e+ +k+ +l + +ad+++ +++
  EEA21989.1 535 SKTIEEFKKSLIEKEKELADLAKHVGNLIEENKKLVDRIVERDQKIGHLNTRIADVSTELQS 596
                 79********************************************************9986 PP

  == domain 5  score: -0.7 bits;  conditional E-value: 0.99
      DUF948  23 klkktldeaaatieelekqvdpilkevedllakvn 57 
                 +l+k+l++ +++  e +++++++ +++    akv 
  EEA21989.1 606 ELNKMLQAHNKQHVEARDRIEALFQNSMSKFAKVF 640
                 45566666666666666666666666655555554 PP

>> FAA_hydrolase_N  Fumarylacetoacetase N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.1         2   3.6e+03      66      90 ..     151     176 ..     147     188 .. 0.59
   2 ?   -0.7   0.1      0.86   1.5e+03      41      67 ..     282     309 ..     266     313 .. 0.74
   3 ?    2.2   0.1      0.11     2e+02      40     103 ..     338     405 ..     322     418 .. 0.71
   4 ?   11.2   0.4   0.00018      0.33      43      82 ..     593     637 ..     575     664 .. 0.76

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 2
                      HHHHHHHHHHHHHHBT.SHHHHT-HH CS
  FAA_hydrolase_N  66 evwravRaalqelLsa.eeelrdnee 90 
                      + +r vR+ l++++++ ++e +d ++
       EEA21989.1 151 ARRRLVRSGLSDVMNRfDSEKKDLKK 176
                      55678999999999554222222222 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.86
                      TGG...SSSGTTSS.SSSHHHHHT-HHH CS
  FAA_hydrolase_N  41 leedaeekesvfsq.ptLnafaalgrev 67 
                      l+++ +ek+++f++ ++Ln + + ++e+
       EEA21989.1 282 LAAARKEKQDLFNEwRKLNPLSSTEPEA 309
                      3456789999997779999999988776 PP

  == domain 3  score: 2.2 bits;  conditional E-value: 0.11
                      ST..GG...SSSGTTSSSSSHHHHHT-HHHHHHHHHHHHHHHBTSH.HHHT-HH.HHHHHEEEGGGEE CS
  FAA_hydrolase_N  40 ql..eedaeekesvfsqptLnafaalgrevwravRaalqelLsaee.elrdnee.lreealvpleeve 103
                      q+  +++ e ++  fs p+++a++a+ r++ +++R++l+   s+e+   r n + + ++ +++l++v 
       EEA21989.1 338 QVlkATQDELNQMGFSGPNIDAILAQMRDTFESAREELKGYRSEEKlPPRFNGKvILKAFIIHLRQVS 405
                      33343445677778999*********************988877443444454445666666666665 PP

  == domain 4  score: 11.2 bits;  conditional E-value: 0.00018
                      G...SSSGTTSSSSSHHHHHT-HHHHHHHHHHHHHHHBT.....S CS
  FAA_hydrolase_N  43 edaeekesvfsqptLnafaalgrevwravRaalqelLsa.....e 82 
                      e +++++++ ++++Ln++++  ++ + ++R ++ +l+++     +
       EEA21989.1 593 ELQSTQADLAKTEELNKMLQAHNKQHVEARDRIEALFQNsmskfA 637
                      455677888899*************************76554431 PP

>> FPP  Filament-like plant protein, long coiled-coil
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.1     0.041        73     790     818 ..     169     197 ..     145     210 .. 0.58
   2 ?    9.3  25.9   0.00015      0.28     649     806 ..     469     629 ..     439     655 .. 0.75

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.041
         FPP 790 eekksheeleakckelqeqlervekkevs 818
                 +ekk  +++ a+++ lq++l ++e+ + s
  EEA21989.1 169 SEKKDLKKAAAEIESLQKKLGSYESAQAS 197
                 44444444444444444444444444433 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.00015
         FPP 649 kvaqk.ges.snecaeisklssekeipselplvsgsneskkeenkllkeeleelksekenlevelksatenleslkaqlqesEqllaelkseLeslkes 745
                 +++++ ++s ++  + ++k  +++e+  + ++ s+ +++++ee++ +k  +++l+ + + +       ++++e+ k  l e+E+ la+l + + +l e 
  EEA21989.1 469 RALKEkEDSiAKLNTALKKYYKDQET--HENIISELEKQQQEEQHISKRRIKDLEDSVNSITNIADYRSKTIEEFKKSLIEKEKELADLAKHVGNLIEE 565
                 22222233434445555566666665..789999999999*********************9999999***************************9999 PP

         FPP 746 kslaetqlkcmkesyesletrateleaelnelkq...kieaLeveLeeekksheeleakckelq 806
                 ++++ + + +  +   +l+tr +++ +el++ +    k+e+L++ L+ ++k h e+  +++ l 
  EEA21989.1 566 NKKLVDRIVERDQKIGHLNTRIADVSTELQSTQAdlaKTEELNKMLQAHNKQHVEARDRIEALF 629
                 99888889999999999*************9985333788999999999999999888877763 PP

>> BAR_3  BAR domain of APPL family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.1       1.3   2.4e+03     127     143 ..     171     187 ..     158     217 .. 0.53
   2 ?    6.1   7.4    0.0045       8.1      24     103 ..     464     547 ..     454     548 .. 0.86
   3 ?   11.3   9.4   0.00011       0.2      12     121 ..     540     650 ..     539     657 .. 0.93

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.3
       BAR_3 127 sekleaaleknaqlskk 143
                  ++l++a++   +l+kk
  EEA21989.1 171 KKDLKKAAAEIESLQKK 187
                 22222222222222222 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.0045
       BAR_3  24 leelekklkkllKlckrlieagkaysaaqkqfaqsLrelkkeskgdeetd....esLkkfsellqelenehtilldqaqrsikk 103
                 l+e+e +lk+   ++ +l +a k+y + q++  + ++el+k++++++ ++    + L+   ++++++++++++ ++++++s+++
  EEA21989.1 464 LQEVERALKEKEDSIAKLNTALKKYYKDQETHENIISELEKQQQEEQHISkrriKDLEDSVNSITNIADYRSKTIEEFKKSLIE 547
                 5566666777777777788999999999999999*********9999999999999***********************99986 PP

  == domain 3  score: 11.3 bits;  conditional E-value: 0.00011
       BAR_3  12 kfResleevEaeleelekklkkllKlckrlieagkaysaaqkqfaqsLrelkkeskgdeetdesLkkfsellqelenehtilldqaqrsikkpLekFrk 110
                 +f++sl e E+el +l k++ +l+ + k+l++   +  +    +++++ +++ e ++ +   +  ++++++lq  +++h +  d+++  ++++++kF+k
  EEA21989.1 540 EFKKSLIEKEKELADLAKHVGNLIEENKKLVDRIVERDQKIGHLNTRIADVSTELQSTQADLAKTEELNKMLQAHNKQHVEARDRIEALFQNSMSKFAK 638
                 599***************************************************99988888999********************************** PP

       BAR_3 111 e.dlkevkekkk 121
                   d+++  ek++
  EEA21989.1 639 VfDIERKNEKRR 650
                 867777777766 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0     0.041        73     143     238 ..     159     190 ..     139     212 .. 0.61
   2 ?   -2.5   0.1         1   1.8e+03     149     215 ..     341     375 ..     318     383 .. 0.40
   3 ?    8.9  16.8   0.00034      0.61     166     289 ..     423     538 ..     406     548 .. 0.71
   4 ?    4.1  11.9    0.0097        17     132     249 ..     533     651 ..     531     658 .. 0.67

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.041
        Spc7 143 gleenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekiee 238
                 gl++ ++ ++++k+ L+k  +e+++l                                                                ++k+ +
  EEA21989.1 159 GLSDVMNRFDSEKKDLKKAAAEIESL----------------------------------------------------------------QKKLGS 190
                 33333344444444444444444444................................................................443333 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 1
        Spc7 149 egleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaei 215
                 ++ +++ +++  +  ++d++                                L+++r++++++ +e+
  EEA21989.1 341 KATQDELNQMGFSGPNIDAI--------------------------------LAQMRDTFESAREEL 375
                 22222222222222223333................................333333333333333 PP

  == domain 3  score: 8.9 bits;  conditional E-value: 0.00034
        Spc7 166 dellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaervleeckgws 264
                 d+l ++++     l +e +k ++++ + ++ d e++  +r +l+e++  ++ek++ +a+l++        +++  +  +++e+ i+e e+ ++e++++s
  EEA21989.1 423 DSLRQQFDYTLILLDKERTKVRNFEGS-KEDDAEDMLRVRMRLQEVERALKEKEDSIAKLNTA-------LKKYYKDQETHENIISELEKQQQEEQHIS 513
                 455555555556666666666665554.44567777777777777777777665555555555.......55555556777889999999999999999 PP

        Spc7 265 esevsrlkeevkaleeltgwkivsl 289
                 +  ++ l+++v+++ ++ + +  ++
  EEA21989.1 514 KRRIKDLEDSVNSITNIADYRSKTI 538
                 ***********99999987776555 PP

  == domain 4  score: 4.1 bits;  conditional E-value: 0.0097
        Spc7 132 WRmqllegLkegleenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeeles..idkeeLeelreelaelkaeieekkkelaelqeq 228
                 +R++ +e+ k++l e+ ++l + ++++ +  ee ++l+++++e+ +++ +  +++ + ++el+s   d ++ eel + l++++++  e +++++ l ++
  EEA21989.1 533 YRSKTIEEFKKSLIEKEKELADLAKHVGNLIEENKKLVDRIVERDQKIGHLNTRIADVSTELQStqADLAKTEELNKMLQAHNKQHVEARDRIEALFQN 631
                 788888888888888888888888888888888888888888888877777777777777766644456666777777777777776677777777666 PP

        Spc7 229 leeleekieelkeqkseleee 249
                   ++ +k+ ++ e+k+e + e
  EEA21989.1 632 SMSKFAKVFDI-ERKNEKRRE 651
                 66666666555.333443333 PP

>> GAS  Growth-arrest specific micro-tubule binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.2    0.0002      0.35      34      85 ..     145     196 ..     144     207 .. 0.90
   2 ?   -0.7   1.2      0.42   7.5e+02      33      67 ..     273     306 ..     269     381 .. 0.52
   3 ?    3.3  12.9     0.026        46      32     104 ..     440     512 ..     408     530 .. 0.83
   4 ?    8.0  14.0   0.00091       1.6      26     143 ..     536     649 ..     528     668 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.0002
         GAS  34 eieelkkkeernekelseisqenkrlkepLkkaeeeveeLrkqlknyekdkq 85 
                 +i + +++ +  +  ls++ ++  + k+ Lkka +e+e L+k+l  ye+ ++
  EEA21989.1 145 QILDARARRRLVRSGLSDVMNRFDSEKKDLKKAAAEIESLQKKLGSYESAQA 196
                 6778888899999999*******************************99776 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.42
         GAS  33 eeieelkkkeernekelseisqenkrlkepLkkae 67 
                 ee+  + +  ++++ke +++ +e ++l+ pL   e
  EEA21989.1 273 EELRMMAEDLAAARKEKQDLFNEWRKLN-PLSSTE 306
                 4444444444444444444444444442.444444 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.026
         GAS  32 KeeieelkkkeernekelseisqenkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkelekelkdl 104
                 + ++ + +  +e +  ++  +  + ++ +  Lk+ e  +++L+ +lk+y kd++ ++n+ ++l+++++e +++
  EEA21989.1 440 RTKVRNFEGSKEDDAEDMLRVRMRLQEVERALKEKEDSIAKLNTALKKYYKDQETHENIISELEKQQQEEQHI 512
                 55566666677788888999999999999******************************99999999886554 PP

  == domain 4  score: 8.0 bits;  conditional E-value: 0.00091
         GAS  26 elIkslKeeieelkkkeernekelseisqenkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkelekelkdlkwehevleqrfekvekerde 124
                 ++I++ K+ + e++k+ +   k++ ++ +enk+l++ + + ++++ +L+ ++++ + + qs ++  a+ +el+k l++   +h   ++   ++e+ +++
  EEA21989.1 536 KTIEEFKKSLIEKEKELADLAKHVGNLIEENKKLVDRIVERDQKIGHLNTRIADVSTELQSTQADLAKTEELNKMLQAHNKQHVEARD---RIEALFQN 631
                 57999**************************************************996555555555555555555555555555555...55555555 PP

         GAS 125 lykkfeaaiqevqqktglk 143
                   +kf + ++++  k + +
  EEA21989.1 632 SMSKFAK-VFDIERKNEKR 649
                 5666655.55555555555 PP

>> NPV_P10  Nucleopolyhedrovirus P10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       2.1   3.9e+03      27      44 ..     171     188 ..     158     195 .. 0.52
   2 ?    2.0   0.0      0.16   2.9e+02      23      66 ..     319     362 ..     315     374 .. 0.85
   3 ?    0.7   5.6      0.41   7.4e+02       8      64 ..     466     530 ..     463     564 .. 0.84
   4 ?    9.4   0.7   0.00078       1.4      11      54 ..     578     621 ..     570     643 .. 0.83

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 2.1
     NPV_P10  27 vddvqenlpdvtelnekL 44 
                  +d+++   +++ l++kL
  EEA21989.1 171 KKDLKKAAAEIESLQKKL 188
                 344444444445555544 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.16
     NPV_P10  23 lqqqvddvqenlpdvtelnekLdaqsaqLaeletkvenIqdiLn 66 
                 ++q v ++++ l++ ++l++ L a +++L+++  +  nI+ iL 
  EEA21989.1 319 MKQIVPRLEAALRTESDLTQVLKATQDELNQMGFSGPNIDAILA 362
                 56778889999999999999999999999999998888888887 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 0.41
     NPV_P10   8 vIradikavddkVdalqqqvddvqenlpdvtelnekLdaqsaqLaelet........kvenIqdi 64 
                  +  + k+ +d +  l++++++  ++ ++ +++ ++L++q+++ +++++        +v++I++i
  EEA21989.1 466 EVERALKEKEDSIAKLNTALKKYYKDQETHENIISELEKQQQEEQHISKrrikdledSVNSITNI 530
                 56678899999999999999999999999999999999999887777666666666678888777 PP

  == domain 4  score: 9.4 bits;  conditional E-value: 0.00078
     NPV_P10  11 adikavddkVdalqqqvddvqenlpdvtelnekLdaqsaqLael 54 
                 + i ++++++  +++++++ q++l +++eln+ L+a ++q  e 
  EEA21989.1 578 QKIGHLNTRIADVSTELQSTQADLAKTEELNKMLQAHNKQHVEA 621
                 45778899999999999999999999999999999988876555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (737 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2411  (0.134475); expected 358.6 (0.02)
Passed bias filter:                      584  (0.0325729); expected 358.6 (0.02)
Passed Vit filter:                        93  (0.00518713); expected 17.9 (0.001)
Passed Fwd filter:                        45  (0.0025099); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 1.12u 0.33s 00:00:01.45 Elapsed: 00:00:00.48
# Mc/sec: 4608.89
//
Query:       EEA21990.1  [L=295]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.6e-27   94.0   0.6    9.5e-27   93.0   0.6    1.6  1  DUF1769   Protein of unknown function (DUF1769)


Domain annotation for each model (and alignments):
>> DUF1769  Protein of unknown function (DUF1769)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.0   0.6   5.3e-31   9.5e-27       1      55 []      93     148 ..      93     148 .. 0.99

  Alignments for each domain:
  == domain 1  score: 93.0 bits;  conditional E-value: 5.3e-31
     DUF1769   1 GddllfGndfdrpirdrlPpgfsaalkfak.fiDpglegDlyadkPylyspllssm 55 
                 G+dl+fGndf+rpird++Ppgf++al+++k  iDpgl+gD yadkPylysp l+s+
  EEA21990.1  93 GNDLMFGNDFNRPIRDSIPPGFNTALRIVKwAIDPGLDGDPYADKPYLYSPGLASW 148
                 89****************************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (295 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       349  (0.0194657); expected 358.6 (0.02)
Passed bias filter:                      309  (0.0172346); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.47
# Mc/sec: 1892.52
//
Query:       EEA21991.1  [L=360]
Description: isocitrate dehydrogenase LysB [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.1e-97  325.1   0.0    7.9e-97  324.5   0.0    1.3  1  Iso_dh    Isocitrate/isopropylmalate dehydrogenase


Domain annotation for each model (and alignments):
>> Iso_dh  Isocitrate/isopropylmalate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  324.5   0.0  4.4e-101   7.9e-97       2     348 .]       8     356 ..       7     356 .. 0.93

  Alignments for each domain:
  == domain 1  score: 324.5 bits;  conditional E-value: 4.4e-101
                 EEEEEESTTHHHHHHHHHHHHHHHHHHHT-EEEEEE---THHHHHHHSSSS-HHHHHHHHHS.SEEEEEE---CSSSSSSHHH.HHHHHHHHTTEEEEE CS
      Iso_dh   2 iallegdgiGpevveaalkvlkaakekaglelefeevdvGgaaidetgeplpeetleaikea.dvvllgavgtpkekevrpen.gLlaLrkeldlfanl 98 
                 i l++gdgiG ev++a  ++l+++ +  gl+++f + d+G  ++++tg++lp++t++ +k++ d +l+gav +p  ++v  ++ +++aLrk ldl+an+
  EEA21991.1   8 IGLIPGDGIGREVIPAGRRLLESLPTSLGLKFSFVDLDAGFDTFKKTGSALPDKTVDTLKKEcDGALFGAVSSPS-TKVAGYSsPIVALRKRLDLYANV 105
                 889********************************************************9988************.56666555*************** PP

                 EEEE-BCCTTCCSSBTHHHHCT-EEEEEEE-SSCGGCSSEEEEETTG.GGGEEEEEEEEEHHHHHHHHHHHHHHHHHT.............TTSEEEEE CS
      Iso_dh  99 rpvkvfeklkvksplkrevveevdlvivReltggiYfgeekekkgsifteevavdtklyseeeieriaraafelAlkr.............gkkkvtlv 184
                 rpvk     + + +        +dlvivRe+t+++Y++eek+++g   +++va  +k++se+++ ria++a e+Al+r              k  vt++
  EEA21991.1 106 RPVKTT--AGGSATGS-----PIDLVIVRENTEDLYVKEEKTIEGP--NGKVAEAIKRISERASFRIATMAGEIALRRqkirqvspgtshlSKPMVTIT 195
                 ****99..44444444.....49**********************8..79*************************99877777777666666788**** PP

                 ESTTTTHHHH.HHHHHHHHHHCC.TTTTSEEEEEEHHHHHHHHHHSGGGGSEEEE-HHHHHHHHHHHHHHTTSGCC-EEEEEETSS-EEEEESS---CC CS
      Iso_dh 185 dKanvlksse.lwrkiveevaee.eypdielehqlvDsaamqlvkspkqfdVivtkNlfGDilSDeaaalvGslGllpSaslgekkvaifEavHGsapd 281
                 +K+nvl++++ l+r+++ + +++ +++ ie+e+q+vDs++++l+++p  +dViv++Nl+GDilSD aaalvGslGl+pSa++g + +ai E++HGsapd
  EEA21991.1 196 HKSNVLSQTDgLFRETARKALADlKFSTIEVEEQIVDSMVYKLFRQPGYYDVIVAPNLYGDILSDGAAALVGSLGLVPSANVG-DDFAIGEPCHGSAPD 293
                 ****************99988888***********************************************************.78************* PP

                 CTTSS-S-THHHHHHHHHHHHHTTT-HHHHHHHHHHHHHHHHH.TSCCHHHCTTSTCCCHHHHHHHHH CS
      Iso_dh 282 iagkdkaNpiavilSaalmLryslgleeaAdkiekAvekvlea.givTkDlageaakevstsefgdav 348
                 i gk++aNpia++ S+almL++ lg+e aA+ki++Av+++l++ +++  Dl+g+a    +t+e+ d+v
  EEA21991.1 294 IEGKGIANPIATLRSVALMLEF-LGEEPAAAKIYAAVDANLDEgKYLSPDLGGKA----TTQEVLDDV 356
                 **********************.********************8899*******9....999998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (360 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       333  (0.0185733); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2492.26
//
Query:       EEA21992.1  [L=395]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.6e-99  331.0   1.8    8.7e-99  330.8   1.8    1.0  1  Peptidase_S58  Peptidase family S58
  ------ inclusion threshold ------
      0.033   14.1   0.1        8.7    6.3   0.0    2.4  2  DUF1455        Protein of unknown function (DUF1455)


Domain annotation for each model (and alignments):
>> Peptidase_S58  Peptidase family S58
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  330.8   1.8  9.7e-103   8.7e-99       1     297 [.      23     371 ..      23     373 .. 0.96

  Alignments for each domain:
  == domain 1  score: 330.8 bits;  conditional E-value: 9.7e-103
  Peptidase_S58   1 naitDVaGvrVghatlaege.vrtGvTvilpr..gnlfkekvvAavdvlnGfgkttgtdqleelglletpivLtntlsvgaaadgvvewlle.... 89 
                    n++ DV+Gv Vg++t++eg+ ++tGvTvilpr  +++   +++Aa++ lnG+g++tgt+ l+e+g ++ pi+Ltnt+svg+++d+++ w le    
     EEA21992.1  23 NSLLDVEGVAVGQKTIHEGQdIHTGVTVILPRgiEKTRLLPCYAATHDLNGMGEMTGTHGLTEWGFISAPIALTNTVSVGKVYDALFLWQLEqgal 118
                    89**************99777***********988888899***************************************************9**9 PP

  Peptidase_S58  90 ...eeeeeearsvvpvVaetnDgvlndiragavkeehvaealaaAaaa.pvaeGnvGaGtGmiafglKGGiGtaSrvleegekeytvgalvqaNfg 181
                       +ee+ + r  +pvVaet+Dg+lndi+a  v+++ v++a++a +++ ++ eGn G+Gt m+++g+KGG+Gt+Sr+++ ++k+yt+g+lvqaN+g
     EEA21992.1 119 agdDEEQIMRRVSIPVVAETFDGLLNDISASVVDKQVVYDAIEASKTQtEILEGNYGGGTAMRCHGYKGGTGTSSRIVPGADKDYTLGVLVQANHG 214
                    9854344888899******************************887777******************************99999************ PP

  Peptidase_S58 182 gredlriagvpvgkelaeea....................kdgsiivvvatDapLskrqlkrlakraalGlartgsp..hsngsGDivlafstaek 255
                    +++dlri +vpvg+ l +e+                    ++gsii+vv tDapL ++ql+r+a++a +G++++g++  ++n+sG+i+la+st+++
     EEA21992.1 215 QKDDLRIGNVPVGEFLLREEakvraaskkeetqfpkggkaAEGSIIIVVVTDAPLLPHQLRRIAQHAGMGVTQVGGHaaGRNFSGEIFLALSTGTS 310
                    **************9999989******************************************************998889*************** PP

  Peptidase_S58 256 epe...................evledeeldelfeaaaeaveeAilnallaAetvtgrdgr 297
                    ++e                   e+l++e +d+lf a+ ea+eeAiln++++Ae +tg++gr
     EEA21992.1 311 PNElatsssgfdylppletqqvETLKNEVIDSLFYATSEATEEAILNSMCRAEPLTGFKGR 371
                    *99*******************99**********************************997 PP

>> DUF1455  Protein of unknown function (DUF1455)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   0.0   0.00098       8.7      17      52 ..      13      48 ..       7      68 .. 0.84
   2 ?    5.4   0.0    0.0019        17      22      63 ..     278     319 ..     263     360 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.00098
     DUF1455 17 lpgslataarpsllrvggeasgqqtsgggfhaagga 52
                 pg + t    sll v g a gq+t   g     g 
  EEA21992.1 13 SPGRFKTGKTNSLLDVEGVAVGQKTIHEGQDIHTGV 48
                699999*******************87776655554 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.0019
     DUF1455  22 ataarpsllrvggeasgqqtsgggfhaaggasatrgrltsas 63 
                 a  a   + +vgg a+g++ sg  f a    ++     ts+s
  EEA21992.1 278 AQHAGMGVTQVGGHAAGRNFSGEIFLALSTGTSPNELATSSS 319
                 4555567889**************999776655555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (395 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       331  (0.0184617); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 2668.11
//
Query:       EEA21993.1  [L=686]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (686 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1091  (0.0608511); expected 358.6 (0.02)
Passed bias filter:                      232  (0.0129399); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.90u 0.37s 00:00:01.27 Elapsed: 00:00:00.56
# Mc/sec: 3676.42
//
Query:       EEA21994.1  [L=140]
Description: hypothetical protein PMAA_057770 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.024   14.9   0.0      0.033   14.4   0.0    1.2  1  LIFR_D2   Leukemia inhibitory factor receptor D2 domain
        0.1   13.3   0.2       0.27   11.9   0.2    1.7  2  AKNA      AT-hook-containing transcription factor


Domain annotation for each model (and alignments):
>> LIFR_D2  Leukemia inhibitory factor receptor D2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   3.7e-06     0.033       8     100 ..      35     132 ..      28     135 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 3.7e-06
     LIFR_D2   8 tpeilsltadfststlilkWndkgsalpeklnviweikvlrk.....eklelvalvtynttlagkdtvlhWnWtsdlPlectshsvrirsyidevkfs 100
                   e  +lt   sts l l+W+++ s ++   +   e k++ +     ++l  ++ +  +++l++  +++ W+  sd   +       ir  i ++kf 
  EEA21994.1  35 ILEDQELTYGASTSNLFLQWQESHSKFEAVDEGSLERKIIATlrslaKTLGELKAQLDQAQLQNLIKMHGWEKVSDGNKDLKEKDTTIRNNIRNLKFC 132
                 45666899999****************9987777665554431112144555566666777888889999******9999999999999999998885 PP

>> AKNA  AT-hook-containing transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.2     3e-05      0.27      12      66 ..      38      95 ..      28     102 .. 0.76
   2 ?   -1.7   0.0      0.54   4.8e+03      31      58 ..     109     136 ..     105     138 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 3e-05
        AKNA 12 eeeylkglrsetlaqklssskgqpgkfdp...sreleaeIyqlgqrleeLkdqtdqlk 66
                 +e + g+    l  + + s+++ +  d    +r++ a++  l + l eLk q dq +
  EEA21994.1 38 DQELTYGASTSNLFLQWQESHSKFEAVDEgslERKIIATLRSLAKTLGELKAQLDQAQ 95
                577778888888888888888887777651115677777789**************98 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.54
        AKNA  31 skgqpgkfdpsreleaeIyqlgqrleeL 58 
                 s g+++  + +  +  +I  l+ +++ L
  EEA21994.1 109 SDGNKDLKEKDTTIRNNIRNLKFCVQML 136
                 4566777777777888888888777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (140 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       857  (0.0477997); expected 358.6 (0.02)
Passed bias filter:                      544  (0.0303419); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.30s 00:00:00.74 Elapsed: 00:00:00.46
# Mc/sec: 914.74
//
Query:       EEA21995.1  [L=156]
Description: hypothetical protein PMAA_057780 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (156 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       538  (0.0300073); expected 358.6 (0.02)
Passed bias filter:                      461  (0.0257125); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.24s 00:00:00.65 Elapsed: 00:00:00.39
# Mc/sec: 1195.64
//
Query:       EEA21996.1  [L=285]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.017   15.0   0.5      0.029   14.3   0.5    1.3  1  PIN_8     PIN like domain


Domain annotation for each model (and alignments):
>> PIN_8  PIN like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.5   1.6e-06     0.029      96     165 ..     206     276 ..     173     278 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 1.6e-06
       PIN_8  96 rkelkkqleelkeelkaeleelkksskadkeedpilkkleel.legkigealskeel.eelvkegekRyenk 165
                 + ++k+ ++ l+++l +  +++k++s+ +k++ ++l+ +++     ki +  +++e+ ++l++e+e+R++++
  EEA21996.1 206 NGQIKQLVTVLENSL-EMRHAAKHQSRPVKDDRNVLQLISAGtQVAKILKDATAMEYlDRLYQETERRVKER 276
                 457888899999999.455555666666668899*****9983458999998888888***********987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (285 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       594  (0.0331307); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1927.98
//
Query:       EEA21997.1  [L=1134]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.1e-47  160.2   0.0    2.1e-46  158.2   0.0    1.9  2  3Beta_HSD        3-beta hydroxysteroid dehydrogenase/isomeras
      9e-35  120.3   0.0    1.7e-34  119.4   0.0    1.4  1  Epimerase        NAD dependent epimerase/dehydratase family
    1.2e-17   64.4   0.0    3.3e-17   62.9   0.0    1.7  1  GDP_Man_Dehyd    GDP-mannose 4,6 dehydratase
      3e-11   43.0   0.0      5e-11   42.2   0.0    1.3  1  RmlD_sub_bind    RmlD substrate binding domain
    8.4e-10   38.2   0.0    1.1e-07   31.3   0.0    2.6  2  NAD_binding_4    Male sterility protein
    3.3e-07   30.3  11.0      8e-07   29.1  11.0    1.7  1  Zn_clus          Fungal Zn(2)-Cys(6) binuclear cluster domain
    3.7e-07   29.5   1.4    1.7e-06   27.3   1.4    1.9  1  Fungal_trans     Fungal specific transcription factor domain
    2.1e-06   27.8   0.3    1.6e-05   24.9   0.3    2.3  1  KR               KR domain
    2.5e-06   27.5   0.0    4.1e-06   26.8   0.0    1.3  1  NAD_binding_10   NAD(P)H-binding
    5.5e-06   25.7   0.5    1.2e-05   24.7   0.1    1.7  2  Polysacc_synt_2  Polysaccharide biosynthesis protein
    0.00061   19.3   0.0     0.0016   18.0   0.0    1.6  1  adh_short        short chain dehydrogenase
  ------ inclusion threshold ------
       0.12   12.6   0.1       0.28   11.4   0.1    1.6  1  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma


Domain annotation for each model (and alignments):
>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.1      0.56   8.3e+02     210     230 ..     302     322 ..     281     332 .. 0.77
   2 !  158.2   0.0   1.4e-49   2.1e-46       1     274 [.     773    1037 ..     773    1043 .. 0.91

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.56
   3Beta_HSD 210 evlsdrvYvgNvawahilAar 230
                  + +d++Y +N ++  + Aa+
  EEA21997.1 302 AIQNDWTYYENTVQNWVRAAQ 322
                 45679*********9999997 PP

  == domain 2  score: 158.2 bits;  conditional E-value: 1.4e-49
   3Beta_HSD    1 vvtGgaGFlGralvkeLvrleelkevrvlDlrespelleelskvnvkkviegDvtdkdkleealegv..dvvihlaslvd....vagkltedeimkv 91  
                  ++tGg+GF+G+a+ +++ + ++     ++D++   ++  ++  ++ + ++++D+t+ +++eea++++   +vih+a++v+     +g+  +  + k+
  EEA21997.1  773 LITGGCGFVGAAIARAITEKHPECRTTIIDINAPGPI--HQVPSQAH-FVKVDITSRAEVEEAIHQIrpTIVIHTAGIVPglaeRFGRRMQSMVWKI 866 
                  69**************999998888889999988888..56666666.99***************99445999**99875222267788889999** PP

   3Beta_HSD   92 nvkGTrnvleacvkagvrvlvYtSsaevvgpnslgeeilngdEeleyeslhqdaypesKalaEklvlkaNgrtlknggrlyTcaLRpagiyGegdkl 188 
                  nv+GTr +l+  ++ gv+++v+tSs+ v  +  +  + +n  Ee++  ++ + +y esKa aE+lvl+a        +++ Tc+LRp+++ G+gd +
  EEA21997.1  867 NVEGTRVMLDVSKRLGVKAFVFTSSCCVLID-DMRLPYRNVTEEWPTSQN-SLIYGESKAAAEELVLQASC------AEMATCSLRPSVLTGPGDYQ 955 
                  *******************************.667899*******98765.789***************98......79****************** PP

   3Beta_HSD  189 lvpllkqlaklglalfkigdeevlsdrvYvgNvawahilAaralqdpkkkssvagqayfisddsPvesyddfnltllkelglelks 274 
                  l+p+++ ++ +g++   +g+ ++  d + v Nva+ah+lAa +l +     +++g+a+fi +++P + + df l +++++g+  + 
  EEA21997.1  956 LLPAIHACIAKGETPWVVGNGQNYWDITLVQNVADAHVLAAENLVST---RTAEGEAFFIQNNEPIT-FRDFCLAIWRDFGHIPPF 1037
                  *********************************************99...7899*************.*************98765 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.4   0.0   1.1e-37   1.7e-34       1     233 [.     772    1003 ..     772    1012 .. 0.91

  Alignments for each domain:
  == domain 1  score: 119.4 bits;  conditional E-value: 1.1e-37
                  EEEETTTSHHHHHHHHHHHHCT..SEEEEEES-STTTTCHHCHHCEEEE--TT-HHHHHHHHHHHT-SEEEE--S.---HHHHHHSHHH..HHHHHT CS
   Epimerase    1 ilVtGatGfiGsalvkallekg..yevigldrlssasntarledlelveldltdrsalerlfkeeqpdavihlAa.vggvaassedpad..fieknl 92  
                  +l+tG+ Gf+G+a+++a+ ek+   + + +d +  +  ++   ++++v++d+t r+++e+++++ +p++vih A+ v g a+++ ++ +  ++++n+
  EEA21997.1  772 VLITGGCGFVGAAIARAITEKHpeCRTTIIDINAPGPIHQVPSQAHFVKVDITSRAEVEEAIHQIRPTIVIHTAGiVPGLAERFGRRMQsmVWKINV 868 
                  79********************55446777777667777777777***************************************9986522789*** PP

                  HHHHHHHHHHHHHTCTEEEEEEEGGGGTSCSSSSBSTCSTTS--.--SSHHHHHHHHHHHHHHHHHHHHT-EEEEEEESEEESTTS-TTSTTSHHHH CS
   Epimerase   93 qgtlnlleaarkagvkrllflsSsevYGkdaeqpkeettltgpl.kpnspYaaaKlageklveayaaqyglnaiilrlfnlyGprngegevsrvipa 188 
                  +gt+ +l+++++ gvk ++f sS++v  +d + p   +t++ p+ + +  Y+ +K+a+e+lv ++  +  + +++lr++ l Gp+     + +++pa
  EEA21997.1  869 EGTRVMLDVSKRLGVKAFVFTSSCCVLIDDMRLPYRNVTEEWPTsQNSLIYGESKAAAEELVLQASCAE-MATCSLRPSVLTGPG-----DYQLLPA 959 
                  ***************************************999**777778*************987777.9**************.....******* PP

                  HHHHHHTTSSSEEEETTST-EEEEEEHHHHHHHHHHHHHHHTT-S CS
   Epimerase  189 lirkilegkqevtllgdgtalRdflyveDvaeaillvlehvdagd 233 
                  + + i++g+    ++g+g++ +d   v+ va+a++l++e+  + +
  EEA21997.1  960 IHACIAKGE-TPWVVGNGQNYWDITLVQNVADAHVLAAENLVSTR 1003
                  *********.*****************************977655 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.9   0.0   2.2e-20   3.3e-17       1     330 [.     773    1102 ..     773    1103 .. 0.77

  Alignments for each domain:
  == domain 1  score: 62.9 bits;  conditional E-value: 2.2e-20
                     EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHHHHT-SEEEE--S---.HHHHT. CS
  GDP_Man_Dehyd    1 LiTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkgDltDssslerllaevqpdevynLAAqsh.Vdvsf. 92  
                     LiTG+ Gf+G+ +a+ + ek+ e+  ++ + ++   g i+++         ++ +++k+D+t ++++e+++++++p+ v++ A+     ++ f 
     EEA21997.1  773 LITGGCGFVGAAIARAITEKHPECRTTIIDINA--PGPIHQVP--------SQAHFVKVDITSRAEVEEAIHQIRPTIVIHTAGIVPgLAERFg 856 
                     9**********************9887654433..35555543........3468*****************************9544888884 PP

                     .TSHHHHHHHHTHHHHHHHHHHHHCT..TTSEEEEEEEGGGG-S-SSSSB...-TTS-----S.HHHHHHHHHHHHHHHHHHHH---EEEEEE- CS
  GDP_Man_Dehyd   93 .ekPeytaevnvlGtlrLLeairalglekkvrfyqaStsEvYGkvqevpq...tEttpfyPrs.PYaaaKlyadwivvnyreayglfavngilf 181 
                       +   ++++nv Gt  +L++ ++lg++    f+++S+  v  +  + p+   tE+ p++ +s  Y+ +K++a+ +v +     ++ +++ + +
     EEA21997.1  857 rRMQSMVWKINVEGTRVMLDVSKRLGVK---AFVFTSSCCVLIDDMRLPYrnvTEEWPTSQNSlIYGESKAAAEELVLQASC-AEMATCSLRPS 946 
                     34556789******************96...7999***999999888776334788888877746************99776.6899******* PP

                     EEESTTS-TTSCCCHHHHHHHHHHTTS-C-EECTTTT-EEEEEEHHHHHHHHHHHHHC......SS---EEE-TT-EEECHHCHHCCHHCCCHH CS
  GDP_Man_Dehyd  182 nhesprrgetfvtrkitravarialgkqevlylGnldakRdwghvkDyveamwlmlqq......dkpedyviatgethsvrefvelaflelgkt 269 
                        +p        ++++ + a ia+g+ +  ++Gn+++  d + v+ +++a +l+ ++       + e + i+++e  + r+f+ +   + g  
     EEA21997.1  947 VLTGPGD-----YQLLPAIHACIAKGETP-WVVGNGQNYWDITLVQNVADAHVLAAENlvstrtAEGEAFFIQNNEPITFRDFCLAIWRDFGHI 1034
                     *****93.....56888888999999865.669******************9988776544444566889999999999999999888888876 PP

                     HHHH................TTGGCCCEECGG--S....S--SB--B-THHHHHHH----SS-HHHHHH CS
  GDP_Man_Dehyd  270 iewegkgeeevg....rakesgkvvvevdpkyfrp....gevdlllgdaskakeeLgWkpkvsfeelvr 330 
                       ++ +  e  +     ++e  +   + +p +          +++++  +ka++ Lg++++ ++ee++r
     EEA21997.1 1035 PPFTVHIPESLAwlagLVAECYT-WFTGTPTTLSRgsvnDACHMRYASGEKARRILGYEARLGLEEGIR 1102
                     66665555554422222333333.233333333330110233566789999999999999999999987 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.2   0.0   3.4e-14     5e-11       3     233 ..     772    1033 ..     770    1044 .. 0.85

  Alignments for each domain:
  == domain 1  score: 42.2 bits;  conditional E-value: 3.4e-14
                     EEEESTTSHHHHHHHHHCTTTSEEEEEE-TT.................T--TTSHHHHHHHHHHH--SEEEE------HHHHHHS....HHHHH CS
  RmlD_sub_bind    3 ilvtGanGqlGseLakqlaeeglevlaltre.................eldltdaeavaellkeakpdvvvnaAAytavDkaEse....eeaay 75  
                     +l+tG+ G +G ++a++++e++ e+ ++  +                 ++d+t +++v+e++++++p +v+++A       aE      +    
     EEA21997.1  772 VLITGGCGFVGAAIARAITEKHPECRTTIIDinapgpihqvpsqahfvKVDITSRAEVEEAIHQIRPTIVIHTAGIV-PGLAERFgrrmQSMVW 864 
                     89******************998877775556699**************************************9875.4567754221266678 PP

                     HHHTHHHHHHHHHHHHCT-E.EEEEEEGGGS-S-TTS-B-TTS----SS....HHHHHHHHHHHHHHH...H-SSEEEEEE-SEESSSSS-HHH CS
  RmlD_sub_bind   76 avnaeavealAeaaaavgal.LihvStDyVFdGekkrpYeeddetsPln....vYGrtKlaGEqavla...agkkalivRtswvygekgknfvk 161 
                     ++n+e+++ + ++ ++ g++ +++ S+  V   +   pY++  e  P +    +YG++K+a E+ vl+   a   ++ +R s++ g  + +++ 
     EEA21997.1  865 KINVEGTRVMLDVSKRLGVKaFVFTSSCCVLIDDMRLPYRNVTEEWPTSqnslIYGESKAAAEELVLQascAEMATCSLRPSVLTGPGDYQLLP 958 
                     9*****************9549*******************9999998755668************9953323345679**************9 PP

                     HHHHHHHH-SEEEEESS.-.EE--EEHHHHHHHHHHHHHHCHH.GGG.-EEEE---BS-EEHHHHHHHHHHHHCH CS
  RmlD_sub_bind  162 tmlrlakereelkvvaD.q.lgsPTsardlAevllqllekaaeekel.agvyHlanegetswlefArailkeaga 233 
                      +    ++ e+  vv   q +   T ++++A++ + ++e+ ++++++  + + + n++ ++  +f  ai +++g 
     EEA21997.1  959 AIHACIAKGETPWVVGNgQnYWDITLVQNVADAHVLAAENLVSTRTAeGEAFFIQNNEPITFRDFCLAIWRDFGH 1033
                     99999988888888754232567899********99999999988877889999999999999999999988765 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0     0.016        23       1      23 [.     774     796 ..     774     806 .. 0.87
   2 !   31.3   0.0   7.1e-11   1.1e-07      89     256 ..     839     991 ..     822     992 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.016
                    EE-TTSHHHHHHHHHHHHHS-.T CS
  NAD_binding_4   1 lTGaTGFLGkvLlekLLrttpev 23 
                    +TG+ GF+G+ + + + +++pe+
     EEA21997.1 774 ITGGCGFVGAAIARAITEKHPEC 796
                    8***************9999987 PP

  == domain 2  score: 31.3 bits;  conditional E-value: 7.1e-11
                    -EEEE--SS-.....S.STTSSE.EHHHHHHHHHHHHHHHTSSS--.-EEEEEEGGGTTS-TTT--SSS-H......HHH--EEEETTTCCCHHHH CS
  NAD_binding_4  89 dviihsaAtv.....nfdepyke.llrvNveGtrevlelakklkklkvllhvSTayvngeregeveekvyeegekeekldederaklkglpntYeq 178
                    +++ih a+ v     +f ++++  ++++NveGtr +l+ +k+l  + ++++ S+ +v  ++ +     +y+       + e+ ++++++    Y  
     EEA21997.1 839 TIVIHTAGIVpglaeRFGRRMQSmVWKINVEGTRVMLDVSKRLGVK-AFVFTSSCCVLIDDMRL----PYR------NVTEEWPTSQNS--LIYGE 921
                    57888888885444456667766478*****************999.*******6666666633....333......355555555554..47*** PP

                    HHHHHHHHHHHHHHHH---EEEEEE-EEE--SSST---TTSHHHHHHHHHHHH-EEES-SB---TT--EEEHHHHHHH CS
  NAD_binding_4 179 sKalaEklvrearrrsglpvvivRpsiitgesktGwingsdlgirgllgliakgvlpeilgdkeavldlvpvDyvana 256
                    sKa+aE+lv +a+   ++ ++ +Rps++tg   +G  +    ++  + ++iakg  p ++g+ ++  d++ v  va+a
     EEA21997.1 922 SKAAAEELVLQASCA-EMATCSLRPSVLTG---PGDYQ----LLPAIHACIAKGETPWVVGNGQNYWDITLVQNVADA 991
                    *************77.999*********99...55444....555889999999999999999999999999998876 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.1  11.0   5.4e-10     8e-07       1      36 [.      20      55 ..      20      59 .. 0.91

  Alignments for each domain:
  == domain 1  score: 29.1 bits;  conditional E-value: 5.4e-10
                SS-HHHHHCT---STSSSS-HHHHHCT..HHHCCCCTC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkkln..leCtfyses 36
                ++C +Cr++Kv+Cd++ P C+ C ++   leC+ y+++
  EEA21997.1 20 QSCVQCRQRKVRCDRGYP-CAPCLRSKssLECS-YDKR 55
                59****************.*****99888****.9876 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   1.4   1.2e-09   1.7e-06       3     248 ..     251     516 ..     249     531 .. 0.77

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 1.2e-09
  Fungal_trans   3 rffsnfhpqfpilhkpsflpkt..ssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeili....hedfsspssslwi 93 
                    + + + p + ilh psf++++  ++++ ++ ++++   ++++la+G+ f   ++ ++ ++ t   q+ +    ra+ l     +++++  ++    
    EEA21997.1 251 CYLKTLEPIYRILHVPSFMTEYeiFWKEARSVPKHFKMKMALVLAIGSAFHAIQNDWTYYENTV--QNWV----RAAQLWlagaSNHANLTND---G 338
                   58899999***********************************************999666665..3444....4444442333333333333...3 PP

  Fungal_trans  94 lq.sLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcdd 189
                   lq   ll+   + +  + + +  +    +++   +gLhr++s   +     l +++ae+r Rlw ++  l ++  l+ G p  l+  + + + Pc+ 
    EEA21997.1 339 LQiGCLLILSRCTCPATLPTWISTA-SLLQMGMMMGLHRDSSLFPS-----LNPFQAEMRNRLWTTIIELSIQALLDSGVPLPLSLAEFDSRNPCNI 429
                   4544444445555555555544444.4559*************985.....*******************************77************* PP

  Fungal_trans 190 ddlwesddaseetlvetk.....lsneeksrkiasfllaLkkilsk........................iagsllsiekqlqqrdlq 248
                   +d+++s    e t++ +       s +   +k  s  l ++++l++                        i+  ++ ++ +++qr+++
    EEA21997.1 430 NDQDISPGSKEATRPKDGhiftdSSIQILLSKSISTRLEIARLLNDpqrknltfekamrlgqelrtacreISA-FFQRNTPTSQRQES 516
                   ***************9878866655555666666666677777777888888888888888888888887777.77777777777777 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.9   0.3     1e-08   1.6e-05       3     141 ..     772     896 ..     771     901 .. 0.83

  Alignments for each domain:
  == domain 1  score: 24.9 bits;  conditional E-value: 1e-08
                 EEEETTTSHHHHHHHHHHHHHH.S-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT- CS
          KR   3 ylitGGlGgLGlelarwlaekg.arhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklleem 100
                 +litGG+G +G ++ar + ek+ + +  ++  +             +++   + ++v++D++++++ve+++++i+   p+i  vih+Ag++  +l e+ 
  EEA21997.1 772 VLITGGCGFVGAAIARAITEKHpECRTTIIDIN---------APGPIHQVPSQAHFVKVDITSRAEVEEAIHQIR---PTI--VIHTAGIV-PGLAERF 855
                 59******************8843333333333.........223345566799********************9...555..9*****98.5899999 PP

                 -HHHHHHHHTTTTHHHHHHHHHTTTS--SEEEEEEEHHHHH CS
          KR 101 taedleqvlapKvkGawnLhelledesldffvlfSSiagll 141
                    +   v +  v+G++++  ++++  ++ fv++SS+  l+
  EEA21997.1 856 GRRMQSMVWKINVEGTRVMLDVSKRLGVKAFVFTSSCCVLI 896
                 99999999****************************98776 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.0   2.8e-09   4.1e-06       1     148 [.     776     950 ..     776     962 .. 0.73

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 2.8e-09
                     TTTSHHHHHHHHHHHHC-.T-EEEEE.ETTHHHCHHHHCTTTCEEEE--TT-CCHHHHHHTT-S..EEEES-........--TCCHHHH...... CS
  NAD_binding_10   1 GAtGkvGrllvkellarg.ghevtal.vRnpeklaeleaeeglevvegdvtdvedlaealkgad..aVvsal........ggggkdeeg...... 77 
                     G+ G vG ++++ + +++ + ++t++ +  p  +++++  ++++ v++d+t+ ++++ea+ ++   +V+ ++                       
      EEA21997.1 776 GGCGFVGAAIARAITEKHpECRTTIIdINAPGPIHQVP--SQAHFVKVDITSRAEVEEAIHQIRptIVIHTAgivpglaeR-------Fgrrmqs 861
                     8889********99999988888888677799999997..79*******************99776888888555544431.......1333334 PP

                     .........HHHHHHHHHHCT--EEEEEEETTTTSGCGCH.....HHHHHHHCCHHHH.HHHHHHHHH.HHHS..SSEEEEEEE-CEE- CS
  NAD_binding_10  78 .........aknivdaakeagvkRfvlvsaigvgdevpge.....fgewnkellkayl.aakraaeel.lras..gldwTivrpggLtd 148
                              ++ ++d+ k+ gvk fv+ s+ +v  + ++      ++ew ++  + ++ + k+aaeel l+as  ++    +rp+ Lt 
      EEA21997.1 862 mvwkinvegTRVMLDVSKRLGVKAFVFTSSCCVLIDDMRLpyrnvTEEWPTSQNSLIYgESKAAAEELvLQAScaEMATCSLRPSVLTG 950
                     456566666**********************9975433221111144454443333344778888887467765588899999999985 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.1   7.7e-09   1.2e-05       1     128 [.     772     891 ..     772     894 .. 0.76
   2 ?   -3.7   0.0       3.3     5e+03     137     154 ..     918     935 ..     915     940 .. 0.81

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 7.7e-09
                      EEEETTTSHHHHHHHHHHHHHB-S.EEEEEES-HHHHHHHHHH......-TTEEEE....E--TT-HHHHHHHTT..T-SEEEE------HH.H CS
  Polysacc_synt_2   1 vlvtGagGsiGselvrqilkkkpk.kiillerdElklyeiekeleeelkkkklkveivpvigdvrdkerlekaleelkvdvvfhaAAlKhVP.l 92 
                      vl+tG+ G +G ++ r i++k+p+ +  +++ +      i++       +     + + v  d++ ++++e+a++++++ +v+h+A +  VP l
       EEA21997.1 772 VLITGGCGFVGAAIARAITEKHPEcRTTIIDINAP--GPIHQVP-----S-----QAHFVKVDITSRAEVEEAIHQIRPTIVIHTAGI--VPgL 851
                      89*******************88634555555433..2333332.....2.....11223579***********************96..8834 PP

                      HHH....SHHHHHHHHHHHHHHHHHHHHHTT-SEEEEEEE CS
  Polysacc_synt_2  93 vee....npleaiktNvlgtenvieaaieagvkkvvliSt 128
                      +e+        ++k Nv gt+ +++++++ gvk++v+ S+
       EEA21997.1 852 AERfgrrMQSMVWKINVEGTRVMLDVSKRLGVKAFVFTSS 891
                      454222134557799**********************996 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 3.3
                      HHHHHHHHHHHHHHHGGG CS
  Polysacc_synt_2 137 vmGatKrlaekllqalak 154
                      ++G +K++ae l+ +++ 
       EEA21997.1 918 IYGESKAAAEELVLQASC 935
                      799*****9999887765 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   1.1e-06    0.0016       3      96 ..     772     855 ..     771     878 .. 0.71

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 1.1e-06
                 EEEESTTSHHHHHHHHHHHHTT-EE..EEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGC CS
   adh_short   3 vlvtGassGIGraiakelakeGakv..vvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfsel 96 
                 vl+tG+++ +G aia+++ ++  ++  +++d+++      + ++ +   +a++++vD+t+r+eve+++ +++       ++++ AGi  +g ++++
  EEA21997.1 772 VLITGGCGFVGAAIARAITEKHPECrtTIIDINAPGP---IHQVPS---QAHFVKVDITSRAEVEEAIHQIR-----PTIVIHTAGI-VPGLAERF 855
                 89******************97655005577775544...555554...6********************94.....4566666666.44444444 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1   0.00019      0.28       2      78 ..     773     846 ..     772     852 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00019
                      EEE--.SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHHHTTS..SEEEE-SS CS
  Sacchrp_dh_NADP   2 liiGa.GsvGqavaellarhfdvdaeitvadrskeklealaakalgvrfeaialdaenyeavLaallkeg..dlvvnlsp 78 
                      li G+ G+vG a+a+ + ++++   + t++d +  +  +       ++++++++d+  +++ +++++ +   ++v++ ++
       EEA21997.1 773 LITGGcGFVGAAIARAITEKHPEC-RTTIIDINAPGPIHQ----VPSQAHFVKVDITSRAE-VEEAIHQIrpTIVIHTAG 846
                      555655***********9999864.***********4333....688999***********.999999888999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1134 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       636  (0.0354733); expected 358.6 (0.02)
Passed bias filter:                      521  (0.0290591); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.91u 0.33s 00:00:01.24 Elapsed: 00:00:00.52
# Mc/sec: 6597.88
//
Query:       EEA21998.1  [L=229]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.4e-08   34.9   0.1    1.8e-08   34.5   0.1    1.3  1  NAD_binding_10  NAD(P)H-binding
      9e-07   28.6   0.0    2.4e-06   27.2   0.0    1.6  1  Epimerase       NAD dependent epimerase/dehydratase family
    1.4e-05   24.7   0.0    2.6e-05   23.8   0.0    1.4  1  HIM1            HIM1
    2.2e-05   24.1   0.6    0.00012   21.7   0.6    2.0  1  NmrA            NmrA-like family
  ------ inclusion threshold ------
      0.094   12.6   0.1       0.19   11.6   0.1    1.5  1  CAP18_C         LPS binding domain of CAP18 (C terminal)
       0.17   11.6   0.1       0.34   10.7   0.1    1.4  1  UVR             UvrB/uvrC motif


Domain annotation for each model (and alignments):
>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.5   0.1     6e-12   1.8e-08       1     150 [.       8     159 ..       8     202 .. 0.74

  Alignments for each domain:
  == domain 1  score: 34.5 bits;  conditional E-value: 6e-12
                     TTTSHHHHHHHHHHHHC-T-E.EEEEETTHHHCHHHHCTTTCEEEE.--TT-CCHHHHHHTT-SEEEES---TCC............HHHHHHHH CS
  NAD_binding_10   1 GAtGkvGrllvkellargghe.vtalvRnpeklaeleaeeglevve.gdvtdvedlaealkgadaVvsalggggk............deegakni 81 
                     G tG vG+++++ lla++g++ ++ + R+   l++++ +++l+v++ +d ++  ++ + l+    V++++ g+ +            d++ ++  
      EEA21998.1   8 GSTGAVGSQILATLLAADGFSsIKTISRR---LPSVQ-SPKLQVLQeVDSSKWGAMISSLSPKPSVIFNAVGTTRadaggiqnqwkiDHDLCIEN 98 
                     89***************976614555555...55553.5899998769999999*9999999998888884333323444444555555559999 PP

                     HHHHHHCT--EEEEEEETTTTSGCGCHHHHHHHHCCHHHHHHHHHHHHHHHHSSSE.EEEEEE-CEE-ST CS
  NAD_binding_10  82 vdaakeagvkRfvlvsaigvgdevpgefgewnkellkaylaakraaeellrasgld.wTivrpggLtdep 150
                     ++aakeagvk +v++s++g+++     f +  +++  +y + k   e+ +++ +++   i+rpg++   +
      EEA21998.1  99 ARAAKEAGVKTYVFISSAGTRN-----FFS--SQV--PYSKMKIGVEDAIKELDFEqAIILRPGMIIGRE 159
                     9******************994.....322..233..777888888888888777646788888876555 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.2   0.0     8e-10   2.4e-06       2     195 ..       5     175 ..       4     207 .. 0.82

  Alignments for each domain:
  == domain 1  score: 27.2 bits;  conditional E-value: 8e-10
                 EEETTTSHHHHHHHHHHHHCT..SEEEEEES-STTTTCHHCHHCEEEE--TT-HHHHHHHHHHHT-SEEEE--S---HHHHHHSHHHHHHHHTHHHHHH CS
   Epimerase   2 lVtGatGfiGsalvkallekg..yevigldrlssasntarledlelveldltdrsalerlfkeeqpdavihlAavggvaassedpadfieknlqgtlnl 98 
                  V G tG +Gs+++  ll+++    + +++r+  + ++ +l+   l e+d  +  a+   ++  +p +++++  vg+ +a +   +  ++++  +  + 
  EEA21998.1   5 AVFGSTGAVGSQILATLLAADgfSSIKTISRRLPSVQSPKLQ--VLQEVDSSKWGAMISSLSP-KPSVIFNA--VGTTRADAGGIQNQWKIDHDLCIEN 98 
                 599************999999866699999997777777777..799**************97.9*******..999999999999************* PP

                 HHHHHHHTCTEEEEEEEGGGGTSCSSSSBSTCSTTS----SSHHHHHHHHHHHHHHHHHHHHT-EEEEEEESEEESTTS-TTSTTSHHHHHHHHHHT CS
   Epimerase  99 leaarkagvkrllflsSsevYGkdaeqpkeettltgplkpnspYaaaKlageklveayaaqyglnaiilrlfnlyGprngegevsrvipalirkile 195
                 + aa++agvk ++f+sS    G  ++     +     + ++ pY+  K+ +e  ++++  ++   aiilr+  ++G     ++ + ++ ++++++++
  EEA21998.1  99 ARAAKEAGVKTYVFISS---AG--TR-----NF----FSSQVPYSKMKIGVEDAIKELDFEQ---AIILRPGMIIGRE---RSKAPMFEKIVENLHK 175
                 *****************...23..22.....22....4677799999999999999876666...8999999999998...4455555555555554 PP

>> HIM1  HIM1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.0   8.8e-09   2.6e-05      50     147 ..      69     163 ..      35     180 .. 0.81

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 8.8e-09
        HIM1  50 tlistLGstsaeekkskvkrkfvdYeLnlklakeFantedKklvivTsfN.nkllskvspYfrtKlklEndLktklepklkeLviLRPGPlvGehtkpi 147
                 ++ +++G+t+a++   +  + ++d++L ++ a++  +   K  v + s   ++++s  +pY ++K+ +E+++k+ l   +++ +iLRPG ++G+ ++++
  EEA21998.1  69 VIFNAVGTTRADAGGIQN-QWKIDHDLCIENARAAKEAGVKTYVFISSAGtRNFFSSQVPYSKMKIGVEDAIKE-L--DFEQAIILRPGMIIGRERSKA 163
                 455788888876655554.789**********************99998526899**************99975.6..579************998754 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.7   0.6     4e-08   0.00012       2     138 ..       5     148 ..       4     154 .. 0.73

  Alignments for each domain:
  == domain 1  score: 21.7 bits;  conditional E-value: 4e-08
                 EESSTTSHHHHHHHHHHHH.HT-.EEEEEES-S-SHHHHHHHHSTTEEE..ES-TT-HHHHHHHHTT-SEEEE---GG.......S-HHHHHHHH.... CS
        NmrA   2 lviGaTGrqGksvvrallk.agh.kvralvRdtkselakslkeaGvelv..kgdlddkeslvealkgvdvvfsvtgfy.......skeiedgkkl.... 85 
                 +v+G+TG+ G+++ + ll+ +g+ +++ + R + s ++ +l+     ++   ++ +  ++++++  +  v+f ++g++       +++ ++  +l    
  EEA21998.1   5 AVFGSTGAVGSQILATLLAaDGFsSIKTISRRLPSVQSPKLQ-----VLqeVDSSKWGAMISSLSPKPSVIFNAVGTTradaggiQNQWKIDHDLcien 98 
                 79**********999988857773478888887665555555.....3321244556678888888888888888877888777755555555555566 PP

                 HHHHHHHS-SEEEEEE---GG.GT.SSS---TTTHHHHHHHHHHHHCTS-EEE CS
        NmrA  86 vdAakeaGvkhfiySslgddndrsnaeepavphfdsKaeieeyvralgipytf 138
                 ++AakeaGvk +++ s +   +       +vp  ++K+ +e+++++l +   +
  EEA21998.1  99 ARAAKEAGVKTYVFISSAGTRNFF---SSQVPYSKMKIGVEDAIKELDFEQAI 148
                 89***********96555555344...457899999**********9887765 PP

>> CAP18_C  LPS binding domain of CAP18 (C terminal)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.1   6.3e-05      0.19       9      27 ..     167     185 ..     167     186 .. 0.93

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 6.3e-05
                 HHHHHHHHHHHHHHHHHHH CS
     CAP18_C   9 eKIgEKLkkIGQKIKDFFq 27 
                 eKI+E L kI Q I+D F+
  EEA21998.1 167 EKIVENLHKISQGIQDSFG 185
                 9***************775 PP

>> UVR  UvrB/uvrC motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.1   0.00011      0.34      12      27 ..     136     151 ..     136     151 .. 0.93

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00011
         UVR  12 eeAaenedFEkAAklR 27 
                 e A++++dFE+A  lR
  EEA21998.1 136 EDAIKELDFEQAIILR 151
                 68**********9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (229 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       401  (0.022366); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.53u 0.32s 00:00:00.85 Elapsed: 00:00:00.50
# Mc/sec: 1373.12
//
Query:       EEA21999.1  [L=1071]
Description: reverse transcriptase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.1e-30  104.6   0.0    1.1e-29  103.6   0.0    1.6  1  RVT_1            Reverse transcriptase (RNA-dependent DNA pol
    1.3e-08   34.7   0.5    3.1e-08   33.5   0.5    1.7  1  Exo_endo_phos_2  Endonuclease-reverse transcriptase
  ------ inclusion threshold ------
      0.011   16.4   0.0      0.043   14.5   0.0    2.1  1  zf-RVT           zinc-binding in reverse transcriptase


Domain annotation for each model (and alignments):
>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.6   0.0   1.8e-33   1.1e-29       3     209 ..     333     540 ..     328     571 .. 0.83

  Alignments for each domain:
  == domain 1  score: 103.6 bits;  conditional E-value: 1.8e-33
                 -TT....S-EEE......-THHHHCTB--...........-------HHHH................HCCHTS--EEEEEEBCCGCCCSBB-GGGGGGG CS
       RVT_1   3 Kkg...pgsyRpisllsvdykalnkliakrLkdvl..ekllsenqpgfrpgrstldav...edllkalkkkkkaklllklDlkkaFdsvpleellrklt 93 
                 Kk+   ++ +Rpislls+++k+l++++a+r++ ++    ll+ n +g r+ rs ++a+   ++   ++++++k   l+++D+++a++ v  e+ll++l+
  EEA21999.1 333 KKNyalAKAWRPISLLSTLGKILEAVVAERISYAVeeFGLLPINHFGARKRRSAEQALlllQEEIYKAWRNRKVLSLVSFDVQGAYNGVFKERLLQRLK 431
                 44478899***************************88889*********************6666667******************************* PP

                 -EEET..........................TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T......TEEECTTEEEEEESSHHHHHHHHHHHHHHH CS
       RVT_1  94 afkvptklinliksflstrsfsvrvnge.eskgryekkglpqGsvlSPllfnlfmnellrelrkrakgvtllrYaDDililskskeelqelleaveewl 191
                 a ++p++++++i +f s r++++ vng+ + ++   ++glpqGs+lSP+lf +f  +l ++  ++  +   ++++DD +  ++++++ +  l       
  EEA21999.1 432 ARGIPDQIVRWIDAFCSRRTANILVNGStSEQRELPQAGLPQGSPLSPILFLFFNADLVQHRISA--SGGAIAFVDDYTAWVSGPSAESLGLG------ 522
                 ****************************77777789***********************999996..899*********99999887433332...... PP

                 HHTT--BEGGG-EEE... CS
       RVT_1 192 kesglkinpeKtklvlft 209
                 k  + +++ +Kt +v+ft
  EEA21999.1 523 KTKRATFECDKTAIVHFT 540
                 333344445555555555 PP

>> Exo_endo_phos_2  Endonuclease-reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.5   0.5   5.2e-12   3.1e-08      64     118 ..       1      56 [.       1      57 [. 0.94

  Alignments for each domain:
  == domain 1  score: 33.5 bits;  conditional E-value: 5.2e-12
  Exo_endo_phos_2  64 leehslsllnllksg.ptfkssngsstiDltltsdnlals..kleleeedlgSDHrpi 118
                      ++ehsl+  +ll++g +t++s ++++tiDl+l+s++la++  k+ ++ +++gSDH++i
       EEA21999.1   1 MTEHSLH--SLLPRGtKTWHSGDTETTIDLVLASTELAEEmvKCGIHYTNHGSDHQAI 56 
                      679****..999999899999999*******************************998 PP

>> zf-RVT  zinc-binding in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.0   7.2e-06     0.043      50      80 ..     977    1006 ..     964    1010 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 7.2e-06
      zf-RVT   50 llkrgiesssrCqlCgqeeEtieHlfleCpf 80  
                  l++ g++ +s  + Cgq+ Et+eH +++C++
  EEA21999.1  977 LNRIGAA-DSDLCACGQASETVEHFLFRCTK 1006
                  5555555.666679***************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1071 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       821  (0.0457917); expected 358.6 (0.02)
Passed bias filter:                      612  (0.0341346); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.84u 0.28s 00:00:01.12 Elapsed: 00:00:00.47
# Mc/sec: 6857.52
//
Query:       EEA22000.1  [L=480]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00012   22.0   2.9    0.00012   22.0   2.9    2.8  2  zf-CCHC   Zinc knuckle
     0.0079   15.3   0.3      0.014   14.5   0.3    1.4  1  BDV_P40   Borna disease virus P40 protein
  ------ inclusion threshold ------
       0.01   15.2   1.4      0.019   14.2   1.4    1.5  1  MPS2      Monopolar spindle protein 2
      0.014   15.8   6.2      0.014   15.8   6.2    2.3  2  DUF16     Protein of unknown function DUF16
       0.02   15.5   6.0       0.02   15.5   6.0    2.5  3  SlyX      SlyX
      0.068   13.7   4.7        8.6    7.0   0.7    3.6  3  HisKA_3   Histidine kinase
       0.26   11.8   2.4       0.72   10.4   1.9    2.0  1  NPV_P10   Nucleopolyhedrovirus P10 protein
       0.83    9.6   4.1       0.71    9.8   1.1    2.5  3  ApoO      Apolipoprotein O
        6.5    6.8  13.5        2.6    8.1   7.2    2.2  2  UPF0242   Uncharacterised protein family (UPF0242) N-terminus


Domain annotation for each model (and alignments):
>> zf-CCHC  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.0   2.9     6e-08   0.00012       2      18 .]     417     433 ..     416     433 .. 0.94
   2 ?    0.7   4.5      0.33   6.7e+02       2      12 ..     436     446 ..     435     451 .. 0.83

  Alignments for each domain:
  == domain 1  score: 22.0 bits;  conditional E-value: 6e-08
                 CTSSSSSSSSTTTTSTS CS
     zf-CCHC   2 kCynCGepGHiardCpk 18 
                 +CynC+e+GH a  C+k
  EEA22000.1 417 QCYNCQEMGHKAFSCKK 433
                 6**************96 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.33
                 CTSSSSSSSST CS
     zf-CCHC   2 kCynCGepGHi 12 
                 +C +C + GH 
  EEA22000.1 436 TCARCANKGHH 446
                 8*********7 PP

>> BDV_P40  Borna disease virus P40 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.3     7e-06     0.014      68     199 ..      58     213 ..      39     228 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 7e-06
     BDV_P40  68 lGlakalvrvgvs.resnlsinterkekrvl....................ligvviGssdeikagakqikrrFkammkaikrpvhs....esadllql 141
                 lG+a a+v+   + r+  ++++ +r  +                       ++  ++G  +e ++g    + + k + + ++   +     + a + q 
  EEA22000.1  58 LGMADAMVEEPATtRSGRVVMPSTRAREASGsdnisavrtskksmtqveltAVKKAAGLIEEKQSGKDGNRDMLKKIGQYLESTYQEvkglKEALIKQE 156
                 577777776544413344455555544444466777777777777778877777788888888887777777777776666555443222356778889 PP

     BDV_P40 142 fnaeeaidWinarplvgslvltlliedfesplpetakelldQiKlVaSyaqmttytTi 199
                    +e  + i+ +++ ++ + t  +e + s++ e  k+l +Q+  VaS+  mtty  +
  EEA22000.1 157 MMIKEQSEMIREQSNTIQALQT-QVEAIRSQATEDYKQLQEQLDTVASTPAMTTYAAV 213
                 999999999****999998888.5678****************************876 PP

>> MPS2  Monopolar spindle protein 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   1.4   9.6e-06     0.019     223     271 ..     148     197 ..      94     216 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 9.6e-06
        MPS2 223 lkta.ikheviisElkrklqeqteiisilkeqiqreeGasqskrkrlhdd 271
                 lk+a ik+e++i+E    ++eq+++i+ l+ q+++ +  +    k+l+++
  EEA22000.1 148 LKEAlIKQEMMIKEQSEMIREQSNTIQALQTQVEAIRSQATEDYKQLQEQ 197
                 444439****************************9877644444555554 PP

>> DUF16  Protein of unknown function DUF16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.8   6.2   7.2e-06     0.014      23      91 ..     132     200 ..     117     207 .. 0.80
   2 ?   -1.9   1.2       2.4   4.8e+03      29      29 ..     284     284 ..     244     326 .. 0.52

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 7.2e-06
                 HHHHHB-..BHHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHHHHHHHHH.......HHHHHHHH CS
       DUF16  23 kqlnefkdsnkqrLkkieakvdklgeqinkleqkvekqgekikelkveqkaqgeelnkvdetlelilet 91 
                 k++ ++ +s+ q++k +++ + k++  i+++ + +++q + i+ l+ +++a + +  +  + l+  l+t
  EEA22000.1 132 KKIGQYLESTYQEVKGLKEALIKQEMMIKEQSEMIREQSNTIQALQTQVEAIRSQATEDYKQLQEQLDT 200
                 677889999999999999999999999999999999999999999999999998777554444444444 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 2.4
                 - CS
       DUF16  29 k 29 
                 k
  EEA22000.1 284 K 284
                 0 PP

>> SlyX  SlyX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.5   6.0     1e-05      0.02       5      52 ..     145     196 ..     141     206 .. 0.82
   2 ?   -1.3   0.1       1.8   3.6e+03      34      52 ..     251     269 ..     248     277 .. 0.64
   3 ?   -2.8   0.2       5.2     1e+04      25      41 ..     294     310 ..     293     313 .. 0.67

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT-....XXXXX CS
        SlyX   5 leeLEiklafqedtieeLndvvaeqqqqidrlqrqlrllaerl....kelee 52 
                 ++ L + l  qe +i+e ++++ eq  +i++lq+q+++++ +     k+l+e
  EEA22000.1 145 VKGLKEALIKQEMMIKEQSEMIREQSNTIQALQTQVEAIRSQAtedyKQLQE 196
                 5667789999******************************999444444444 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.8
                 HHHHHHHHHHHHT-XXXXX CS
        SlyX  34 drlqrqlrllaerlkelee 52 
                 d+ ++q++ +++++++   
  EEA22000.1 251 DKAKTQIANIRQQIEKEMR 269
                 6777888888888844333 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 5.2
                 HHHHHHHHHHHHHHHHH CS
        SlyX  25 vvaeqqqqidrlqrqlr 41 
                 vv +++++++++++  +
  EEA22000.1 294 VVCRHEDEMQQIKEAAQ 310
                 67778888877776554 PP

>> HisKA_3  Histidine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.1     0.014        28      17      60 ..     107     149 ..     101     156 .. 0.71
   2 ?    7.0   0.7    0.0043       8.6      16      47 ..     172     203 ..     162     208 .. 0.91
   3 ?    0.2   0.0      0.57   1.1e+03      34      52 ..     249     267 ..     234     270 .. 0.79

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.014
                 HHHHHHHHHHHHHHTTT-HHHHHHHHHHHHHHHHHHHHHHHHHH CS
     HisKA_3  17 LsaiklqlelakrllekdpekaaeqlreieelarealqevRrll 60 
                 L+a+k  ++l++++ ++ ++  +++l++i + +++++qev+ l 
  EEA22000.1 107 LTAVKKAAGLIEEK-QSGKDGNRDMLKKIGQYLESTYQEVKGLK 149
                 55555555555533.3455599******************9775 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0043
                 HHHHHHHHHHHHHHHTTT-HHHHHHHHHHHHH CS
     HisKA_3  16 sLsaiklqlelakrllekdpekaaeqlreiee 47 
                 ++ a++ q+e+++ ++++d ++++eql+++++
  EEA22000.1 172 TIQALQTQVEAIRSQATEDYKQLQEQLDTVAS 203
                 67899***********************9976 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.57
                 -HHHHHHHHHHHHHHHHHH CS
     HisKA_3  34 dpekaaeqlreieelarea 52 
                 +++ka++q+++i++++++ 
  EEA22000.1 249 EQDKAKTQIANIRQQIEKE 267
                 45699999***99998875 PP

>> NPV_P10  Nucleopolyhedrovirus P10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   1.9   0.00036      0.72      13      48 ..     166     202 ..     157     215 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00036
     NPV_P10  13 ikavddkVdalqqqvddvqenl.pdvtelnekLdaqs 48 
                 i++ ++ ++alq+qv+ ++++  +d ++l+e+Ld  +
  EEA22000.1 166 IREQSNTIQALQTQVEAIRSQAtEDYKQLQEQLDTVA 202
                 78889999**********9885278999999999875 PP

>> ApoO  Apolipoprotein O
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       2.8   5.6e+03      41      67 ..      77     102 ..      68     123 .. 0.62
   2 ?    9.8   1.1   0.00036      0.71       9      44 ..     169     204 ..     155     246 .. 0.82
   3 ?   -1.4   0.0       1.1   2.1e+03      12      32 ..     249     269 ..     238     284 .. 0.78

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 2.8
        ApoO  41 vkskvetaeqsvtdtiasLkeppedll 67 
                 v+++    e s++d+i+ +  + ++ +
  EEA22000.1  77 VMPSTRAREASGSDNISAVRTS-KKSM 102
                 5666666666666666666654.4444 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00036
        ApoO   9 seeptdrLeegvrslRkslepytsavqdelnkvksk 44 
                 +++  ++L+++v+ +R ++++ ++++q++l++v s 
  EEA22000.1 169 QSNTIQALQTQVEAIRSQATEDYKQLQEQLDTVAST 204
                 368899************************998764 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 1.1
        ApoO  12 ptdrLeegvrslRkslepyts 32 
                 ++d+ +++++++R+++e+++ 
  EEA22000.1 249 EQDKAKTQIANIRQQIEKEMR 269
                 677788899999999988765 PP

>> UPF0242  Uncharacterised protein family (UPF0242) N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   7.2    0.0013       2.6      69     145 ..     116     199 ..      92     223 .. 0.73
   2 ?    2.3   0.4     0.076   1.5e+02      66     129 ..     249     312 ..     231     323 .. 0.72

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0013
     UPF0242  69 kleekeaklteldeglktkeealeelqeeeeeLkee.......ldakeeelerlkeenqqLqekleaiaedfeelkleleeqLa 145
                  +eek++    +++ lk++ + le   +e + Lke        +++++e +++  +  q Lq + eai  +  e  ++l+eqL+
  EEA22000.1 116 LIEEKQSGKDGNRDMLKKIGQYLESTYQEVKGLKEAlikqemmIKEQSEMIREQSNTIQALQTQVEAIRSQATEDYKQLQEQLD 199
                 445555555555577888888888888888888888777777788888888888888888888888888888888888888886 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.076
     UPF0242  66 ekskleekeaklteldeglktkeealeelqeeeeeLkeeldakeeelerlkeenqqLqekleai 129
                 e+ k ++++a++ ++ e+ +  +e+ e+ +   +    + + + + + r++ e qq++e +++i
  EEA22000.1 249 EQDKAKTQIANIRQQIEKEMRGNEETENWRCAAMIKDPKTADRIKVVCRHEDEMQQIKEAAQKI 312
                 5556666666666666666666666666666666666669999999999999999999888775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (480 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2197  (0.122539); expected 358.6 (0.02)
Passed bias filter:                      681  (0.0379832); expected 358.6 (0.02)
Passed Vit filter:                        90  (0.0050198); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.68u 0.31s 00:00:00.99 Elapsed: 00:00:00.46
# Mc/sec: 3118.58
//
Query:       EEA22001.1  [L=449]
Description: monocarboxylate permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-27   96.1  64.9      9e-21   74.2  36.2    2.1  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.2  36.2     5e-25     9e-21       4     317 ..      66     365 ..      58     368 .. 0.80
   2 !   35.9  20.7   2.2e-13   3.9e-09      54     173 ..     316     437 ..     315     447 .. 0.79

  Alignments for each domain:
  == domain 1  score: 74.2 bits;  conditional E-value: 5e-25
       MFS_1   4 aaflsalarsilgpalpl.alaedlg.ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll.fasslw.lllvlrvlqGlg 98 
                 aa+++++++++ + ++   + +++l  +s s++++++++ +++++++++++G + d +G+r  l++g ++ ++g l+++ ++  ++ ++l   v++G+g
  EEA22001.1  66 AALFTSFGWTNCIGLFQDeYQSNQLKeYSSSTVSWITSVQFFFMLAMAPVAGKIFDSYGPRIPLFAGSVAHVFG-LMMTsLCKEYYqFFLSQSVVSGIG 163
                 445555555555555554455555558***********************************************.6666577888889*********** PP

       MFS_1  99 agalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeeekgtgpaplv 197
                 a+++f+ ++++   +f k +rg a gl  +g+slG ++ pl    l+ ++g+ +++ i+a++ l ++v++ + +    p ++r+           +++ 
  EEA22001.1 164 ASFIFTPALSAPQTYFRK-RRGVAAGLSVGGSSLGGVIFPLMVQHLLPQVGFGWTMRICAFLILGMLVVANVCISSALPHKPRP-----------FHFM 250
                 *****************9.***********************************************886444444444444444...........3344 PP

       MFS_1 198 pawkallkdpvlwillialllfffgfsg..lltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglall 294
                 + + a lkd  +  l++++  ff+++++   + ++ + +  ++g+s  +la  l+++l  +++i++ l  +++d+ gr + ++++ +l ++++l+l l 
  EEA22001.1 251 Q-YIAPLKDLNF--LVLCISEFFMFLAMliPFDFIVT-AAIRYGMS-TYLAWCLVPILNGASLIGRTLPNYIADKSGRFNVMTMMSGLSTILVLALWLP 344
                 4.3334555555..55555555555555554444444.49******.8****9**********************999777777777777777777777 PP

       MFS_1 295 avtssavllllvlvliGfglgfv 317
                 ++   +++++++ +++Gf +g v
  EEA22001.1 345 GHN--NAAIICFAAFFGFSSGGV 365
                 777..999999*******66655 PP

  == domain 2  score: 35.9 bits;  conditional E-value: 2.2e-13
       MFS_1  54 rlsdrfGrrrvlllglllfalglllllfa.sslwlllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllgglla..sslg 149
                 +++d+ Gr  v+ ++  l+ + +l+l+++ ++  +++ + ++ G+ +g+++ +g +lia ++p +e g+ +g+++a++s+Ga+ gp+++g+++  ++++
  EEA22001.1 316 YIADKSGRFNVMTMMSGLSTILVLALWLPgHNNAAIICFAAFFGFSSGGVIGLGPSLIATISPMNEIGFRMGVFMAFVSIGALAGPPAAGAIIsaDNGS 414
                 789***99997777777777774666665688789999999********************************************99999888344444 PP

       MFS_1 150 Wravfyilaivsllafvlfllllp 173
                 ++ v ++ ++ +++a + ++++l+
  EEA22001.1 415 YTFVAVLSGLCFAIATI-GMAFLR 437
                 65555555555555555.445544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (449 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       580  (0.0323498); expected 358.6 (0.02)
Passed bias filter:                      271  (0.0151152); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.49
# Mc/sec: 2778.60
//
Query:       EEA22002.1  [L=180]
Description: 40S ribosomal protein S8 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.3e-10   40.5   0.0    2.9e-09   36.9   0.0    2.3  1  Ribosomal_S8  Ribosomal protein S8


Domain annotation for each model (and alignments):
>> Ribosomal_S8  Ribosomal protein S8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.9   0.0   1.6e-13   2.9e-09       3     126 ..       6     179 ..       4     179 .. 0.85

  Alignments for each domain:
  == domain 1  score: 36.9 bits;  conditional E-value: 1.6e-13
                   HHHHHHHHHHHHHTT-SEEEEE--HHHHHHHHHHHHCTSEEEEEEECCC...................................CCC.....EEEEE CS
  Ribosomal_S8   3 iadmltrirNaekakkeevevpasklkeeilkvLkeeGyikdfeveeek...................................kkk.....ikiel 59 
                   +a m ++++N +ka+   +++  +k++++++  ++++G i ++    ++                                     +     + + l
    EEA22002.1   6 LAHMYSHLNNVTKARLGLTSIVDTKMHRSLILAMQQQGLIGSIVRGGRSpppphlllgqptatsaadastsaasgvietepvtqA-NiatrrLWLGL 101
                   799****************************************99644479*********9999999988888888777766551.15666699*** PP

                   -BSSS-SBSSSEEEE-SBTTC--EE-CCC---CGGGT............SEEEEEETTEEEEHHHHHHCT--EEEEEEE CS
  Ribosomal_S8  60 kynkkkksvikklkrvskpgrrvYakvkelpkvlngl............GiaivsTskGvmtdkeArkkkvGGevlayv 126
                   ky + +++v+ k++ vskp rr+ ++   l++v +g              ++ ++T++G++  +++ +kk+GG vl+ v
    EEA22002.1 102 KYWQ-SEPVLGKITPVSKPTRRIIMDLPALRRVIRGSrsgtveglrspgECLFLATDRGILEARQCVEKKIGGVVLCRV 179
                   **99.79*************************9988533222222222235799***********************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (180 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       270  (0.0150594); expected 358.6 (0.02)
Passed bias filter:                      245  (0.013665); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.44
# Mc/sec: 1217.30
//
Query:       EEA22003.1  [L=388]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (388 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       599  (0.0334096); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.23s 00:00:00.73 Elapsed: 00:00:00.41
# Mc/sec: 2829.68
//
Query:       EEA22004.1  [L=510]
Description: kynurenine 3-monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.8e-19   68.3   0.0    4.1e-18   65.8   0.0    2.1  1  FAD_binding_3   FAD binding domain
    7.5e-05   22.1   0.0    0.00014   21.2   0.0    1.3  1  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    0.00089   19.8   0.1      0.055   14.0   0.0    3.0  3  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
     0.0017   17.7   0.0     0.0028   17.0   0.0    1.3  1  AlaDh_PNT_C     Alanine dehydrogenase/PNT, C-terminal domain
     0.0024   17.5   0.1     0.0099   15.5   0.0    2.0  2  DAO             FAD dependent oxidoreductase
     0.0026   18.0   0.1     0.0068   16.6   0.1    1.7  1  NAD_binding_8   NAD(P)-binding Rossmann-like domain
      0.003   16.3   0.0      0.005   15.6   0.0    1.3  1  HI0933_like     HI0933-like protein
     0.0047   16.0   0.0     0.0084   15.2   0.0    1.4  1  GIDA            Glucose inhibited division protein A
  ------ inclusion threshold ------
       0.11   11.9   2.4       0.18   11.1   0.3    2.2  3  FAD_oxidored    FAD dependent oxidoreductase
       0.11   11.3   0.0        1.1    8.1   0.0    2.1  2  Trp_halogenase  Tryptophan halogenase
       0.12   12.3   0.0       0.24   11.3   0.0    1.5  1  3HCDH_N         3-hydroxyacyl-CoA dehydrogenase, NAD binding 
       0.14   11.2   0.0       0.25   10.4   0.0    1.4  1  SE              Squalene epoxidase
       0.15   11.4   0.0        3.2    7.1   0.0    2.2  2  ThiF            ThiF family


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.8   0.0   2.9e-21   4.1e-18       3     318 ..       8     363 ..       6     404 .. 0.69

  Alignments for each domain:
  == domain 1  score: 65.8 bits;  conditional E-value: 2.9e-21
                    EEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSSS--EEEHHHHHH.HHHTT-HHHHHH..HSEECCCCEEEEEEE...CCCC......CEE CS
  FAD_binding_3   3 dVlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlpradglnqrtmel.lrqlGledrila..egapnelmgealyne...lsdt......pka 86 
                    +V+IVGaGp+G ++al  +++G +v + + r++  + +      +++++l l ++G+    l+  e++++++m++a       ++++       +a
     EEA22004.1   8 KVVIVGAGPVGSLAALYAASRGDDVEVYDLRADLRDPSTVPLNFTKSINLaLSERGIHSMHLSgrEDVVHKIMSQAIPMHgrmIHGRdltgnlWQA 103
                    7***********************999998887776666666667788765888888766553225556666666655555553333556633333 PP

                    EEEHHCHHCST-CEE--HHHHHHHHHHHHHHHT.EEETCSEEEECCEECCCCCCCEEE..................ECCTTEE.....EEEEEEEE CS
  FAD_binding_3  87 radlelesspervtvypqteleriLvehaeerg.lqvrfktevesleqdeegvtaevr..................dketgee.....etvrakYl 158
                          +  ++++  +    l+++L++++e+++ +++ f++++++   ++ +   e r                  d            +v+ ++l
     EEA22004.1 104 AQA--YDVHGQAINSIDRATLNNALLDELEKTPnVKLFFNHKLTGADFHTRKAWFERRipedehktdyphpddasvD-----FdrapeVEVSFDFL 192
                    344..5599999******************************87544444443334445555444444444444442.....04444478****** PP

                    EE--GTT-HHHHHHTGGEEEEEEEEEEEEEEEEEEC.-SCCCTTC......CEEEEECCTTEE..EEEECCE.TEEEEEEEEECCE-GGGSCCCH. CS
  FAD_binding_3 159 vGaDGgrStvrktlgiefegeetvyeagvldvlfda.dlsdivep......lvlilsaesrgv..mviPlen.tlerfyvqvearaekeersekf. 243
                    +GaDG++S++r  +    + ++ +y+ + +d+l  + +++ + e+      ++l + + ++++  ++ + ++ +       ++ +a+ ++++e+  
     EEA22004.1 193 IGADGAHSASRYHMM---KYSRVDYQQEYIDTLWCEfRIEPTKEGdfrispNHLHIWPGKEFMfiALPSPDKsFTCTLFAPADHYAQLGNTPEALc 285
                    **********98764...334444445555555444444433343444445455544544442225555555455555555666666666666541 PP

                    ..HHHHHHHHHHHHHTTSSCEEEEEEEEEEEEEEEEESSSEET.TEEE-GGGTEEE-STTSHHHHHHHHHHHHHHHHH CS
  FAD_binding_3 244 ..teeevkarlreivgektldveieevsawtvaqrvaekyrkg.rvflaGDAaHihpPtgGqGlNtaiqDavnLawkL 318
                      +++      +e++ +++l  +++  +++++ +  +++ + +  v ++GDAaH++ P  GqGlN +++D+  L+  L
     EEA22004.1 286 ksFQQYFPGVSPELISPEDLYRQFTTNQHLPLISIKCKPHHYDsSVVIIGDAAHAVLPFYGQGLNAGMEDVRVLFEIL 363
                    114444445567899999*************************9****************************999887 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.0     1e-07   0.00014     142     202 ..       6      68 ..       2      82 .. 0.91

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 1e-07
                  TSEEEEES-SHHHHHHHHHHHHHT-EEEEEESSSSSS..TTS-HHHHHHHHHHHHHTTEEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 142 pkrivvvGgGyiGvElAaalaklgkevtlveardrll..raldkelsaaleealekeGvevkl 202
                  ++++v+vG+G++G+  A ++a+ g++v + + r  l   ++++ ++++ ++ al ++G++ ++
   EEA22004.1   6 RQKVVIVGAGPVGSLAALYAASRGDDVEVYDLRADLRdpSTVPLNFTKSINLALSERGIHSMH 68 
                  589***********************************99*******************8765 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.0   0.0     4e-05     0.055       1      56 [.       8      65 ..       8      78 .. 0.84
   2 ?    1.0   0.0      0.45   6.3e+02      41      67 ..     121     148 ..     113     155 .. 0.85
   3 ?    0.0   0.0      0.93   1.3e+03      37      71 ..     368     402 ..     351     406 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 4e-05
                EEEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSS..TTSSHHHHHHHHHHHHHTTEE CS
   Pyr_redox  1 kvvvvGgGyiglElAgalaelgkkVtvversdkll..rllDeeaskilqeklekngie 56
                kvv+vG+G +g  +A ++a  g++V v + +  l+  +  +  + k +   l+++gi+
  EEA22004.1  8 KVVIVGAGPVGSLAALYAASRGDDVEVYDLRADLRdpSTVPLNFTKSINLALSERGIH 65
                79**************************999999976666777777777777777765 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.45
                 HHHHHHHHHHHHT.TEEEECSEEEEEEE CS
   Pyr_redox  41 easkilqeklekn.gievllntkveeie 67 
                 ++ ++l ++lek  ++++ +n+k++  +
  EEA22004.1 121 TLNNALLDELEKTpNVKLFFNHKLTGAD 148
                 5778999***************998765 PP

  == domain 3  score: 0.0 bits;  conditional E-value: 0.93
                 TSSHHHHHHHHHHHHHTTEEEECSEEEEEEEEETT CS
   Pyr_redox  37 llDeeaskilqeklekngievllntkveeiegsed 71 
                 ++D +  ++ ++k ++   e +++t+v+ ++  +d
  EEA22004.1 368 VYDVTHDAASRDKARNAAFETYTKTRVVDVHAIND 402
                 67777788899999999**********99987665 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0   2.1e-06    0.0028      28      64 ..       6      42 ..       3      77 .. 0.90

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 2.1e-06
                 --EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHHHH CS
  AlaDh_PNT_C 28 pakvlviGgGvaGlqAiatakglgakVtvlDvrparl 64
                 + kv+++G+G +G  A+  a++ g +V+v+D+r++ +
   EEA22004.1  6 RQKVVIVGAGPVGSLAALYAASRGDDVEVYDLRADLR 42
                 569*****************************98765 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   7.2e-06    0.0099       1      27 [.       8      36 ..       8      45 .. 0.90
   2 ?   -1.4   0.0      0.97   1.3e+03     242     242 ..     170     170 ..     115     327 .. 0.56

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 7.2e-06
                EEEEECTSHHHHHHHHHHHHTT..EEEEE CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..Vtlle 27
                +vvi+G+G +G+ +A+++a rg  V +++
  EEA22004.1  8 KVVIVGAGPVGSLAALYAASRGddVEVYD 36
                59*******************99998887 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.97
                 E CS
         DAO 242 p 242
                 p
  EEA22004.1 170 P 170
                 1 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.1   4.9e-06    0.0068       1      31 [.      11      41 ..      11      42 .. 0.95

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 4.9e-06
                   EE--SHHHHHHHHHHHCCTEEEEEE-SSSSS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekrdrl 31
                   IvGaG  G++aA ++a +g dv++++ r +l
     EEA22004.1 11 IVGAGPVGSLAALYAASRGDDVEVYDLRADL 41
                   9*************************99875 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   3.6e-06     0.005       2      31 ..       8      37 ..       7      42 .. 0.92

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 3.6e-06
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-S CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVlllek 31
                 +v+++G+G+ G +aA+ aa+rg +V +++ 
   EEA22004.1  8 KVVIVGAGPVGSLAALYAASRGDDVEVYDL 37
                 89*************************995 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   6.1e-06    0.0084       1     114 [.       8     139 ..       8     145 .. 0.70

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 6.1e-06
                 CEEEE-SSHHHHHHHHHHHHTT--EEEE................ES-GGGTT--SSSSEEE-T....THHHHHHHHHHHT-SHHHHHHHHEEEEEE..E CS
        GIDA   1 dviViGgGhAGceAAlaaarlGakvlLi................thkldtiaelsCnpsiggi....akgllvrEidalggliikaadkagiqfri..l 77 
                 +v+++G+G  G+ AAl aa +G +v  +                t++++  ++     s+        + +++ +   + g +i+  d +g   +    
  EEA22004.1   8 KVVIVGAGPVGSLAALYAASRGDDVEVYdlradlrdpstvplnfTKSINLALSERGIHSMHLSgredVVHKIMSQAIPMHGRMIHGRDLTGNLWQAaqA 106
                 69**************************99999999998887774444444444444455544323345555555566778888888877753332002 PP

                 STTS-CCC-EEEEEE-HHHHHHHHHHHHHTSTTEEEE CS
        GIDA  78 NrskGpavralraqvdrelyskevteklenepnleii 114
                    +G+a++    ++dr + ++++ ++le++pn++++
  EEA22004.1 107 YDVHGQAIN----SIDRATLNNALLDELEKTPNVKLF 139
                 333444444....559999999999999999999987 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.3   0.00013      0.18       2      25 ..       9      32 ..       8      38 .. 0.93
   2 ?   -0.9   0.0       0.6   8.2e+02      83     115 ..     116     149 ..      78     166 .. 0.70
   3 ?   -2.2   0.1       1.5     2e+03     248     298 ..     404     455 ..     363     461 .. 0.59

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00013
  FAD_oxidored  2 vvVvGGgpaGvaAAiaAaraGakv 25
                  vv+vG+gp G  AA+ Aa +G  v
    EEA22004.1  9 VVIVGAGPVGSLAALYAASRGDDV 32
                  9********************987 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.6
  FAD_oxidored  83 tfepevakavleeml.aeagvtvllntrlvevek 115
                   + +  +++++l + l + ++v++++n++l++++ 
    EEA22004.1 116 SIDRATLNNALLDELeKTPNVKLFFNHKLTGADF 149
                   4555555555444444889999999999988765 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 1.5
  FAD_oxidored 248 vstdli.enldlpeaeyegreqireeareltqgllkylqteewgfekaeleg 298
                    + ++i +  ++    y+ r+ i e++ ++   l +  q  +  f+++++++
    EEA22004.1 404 SKGNFIeMRAGVNSRWYKLRKFIEENLDRYMPQLGWRTQYSRVSFSNMRYSE 455
                   2233333456666666777777777777787777777776677777777665 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.0   0.00078       1.1       1      22 [.       8      29 ..       8      40 .. 0.83
   2 ?    0.6   0.0      0.15     2e+02     314     360 ..     327     373 ..     304     391 .. 0.84

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00078
                    EEEEE--SHHHHHHHHHHHHHT CS
  Trp_halogenase  1 kivivGGGtaGwlaAaalakal 22
                    k+vivG+G+ G+laA + a  +
      EEA22004.1  8 KVVIVGAGPVGSLAALYAASRG 29
                    79*************9988776 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.15
                     EETTEEE-CCCTEE--CCCS-HHHHHHHHHHHHHHT--BTT--HHHH CS
  Trp_halogenase 314 wvknvvalGlasgfvePlestsihliqaalrrLlallpdksdepaai 360
                     +   vv +G+a+ +v P  ++++   ++++r L ++l ++++ +++ 
      EEA22004.1 327 YDSSVVIIGDAAHAVLPFYGQGLNAGMEDVRVLFEILDSHGVYDVTH 373
                     67789******************************998887766654 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00017      0.24       1      33 [.       8      40 ..       8      55 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00017
                EEEEE--SCCHHHHHHHHHHTT-EEEEE-S-HH CS
     3HCDH_N  1 kvaviGaGtmGagiaavfasagleVvlvdisee 33
                kv ++GaG +G+  a  +as+g +V ++d +++
  EEA22004.1  8 KVVIVGAGPVGSLAALYAASRGDDVEVYDLRAD 40
                699**************************9876 PP

>> SE  Squalene epoxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   0.00018      0.25     130     198 ..     329     404 ..     294     424 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00018
          SE 130 kGlillGDalnmRHPltggGmtvalnDivllskllkpl......edlsdeekvleelksfyvkRkelda.vvnvLs 198
                 + ++++GDa     P  g G+  +++D+ +l ++l         +d   ++k  ++  + y+k + +d+  +n Ls
  EEA22004.1 329 SSVVIIGDAAHAVLPFYGQGLNAGMEDVRVLFEILDSHgvydvtHDAASRDKARNAAFETYTKTRVVDVhAINDLS 404
                 6799******************************987644222233333333333333334444444433555555 PP

>> ThiF  ThiF family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.0    0.0023       3.2      18      39 ..       6      27 ..       2      34 .. 0.88
   2 ?    2.0   0.0     0.083   1.1e+02     180     208 ..     410     492 ..     257     509 .. 0.65

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0023
                TSEEEEE--SHHHHHHHHHHHH CS
                xxxxxxxxxxxxxxxxxxxxxx RF
        ThiF 18 dskvllvGaGglGsellknLal 39
                ++kv++vGaG +Gs ++ + a 
  EEA22004.1  6 RQKVVIVGAGPVGSLAALYAAS 27
                589*************988765 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.083
                 H..........................................................HHHCTE-B-HHHHHHHHHHHHHHHHHHH CS
                 x..........................................................xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        ThiF 180 t..........................................................siagnipaiatttavvaglaalellkll 208
                 +                                                          +  g    +a +ta+v+gla+  ++ + 
  EEA22004.1 410 EmragvnsrwyklrkfieenldrympqlgwrtqysrvsfsnmryseimraverqrllltASLG----MAVFTALVSGLAVGSTMMWR 492
                 044444444444444444444444444444444444444444444444433333333336666....99999999999999998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (510 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       552  (0.0307881); expected 358.6 (0.02)
Passed bias filter:                      507  (0.0282782); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.65u 0.27s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 3387.82
//
Query:       EEA22005.1  [L=399]
Description: methionine aminopeptidase, type I, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-47  162.3   0.0    1.5e-47  162.0   0.0    1.1  1  Peptidase_M24  Metallopeptidase family M24
    6.7e-20   71.1   7.3    1.6e-19   69.9   7.3    1.7  1  zf-C6H2        zf-MYND-like zinc finger, mRNA-binding
    0.00062   19.8   5.2    0.00062   19.8   5.2    2.3  2  zf-MYND        MYND finger
  ------ inclusion threshold ------
       0.24   11.3   3.3       0.57   10.1   3.3    1.7  1  zf-HIT         HIT zinc finger


Domain annotation for each model (and alignments):
>> Peptidase_M24  Metallopeptidase family M24
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  162.0   0.0   3.3e-51   1.5e-47       1     209 []     138     369 ..     138     369 .. 0.89

  Alignments for each domain:
  == domain 1  score: 162.0 bits;  conditional E-value: 3.3e-51
                    HHHHHHHHHHHHHHHHHHHHHHTTCBHHHHHHHHHHHHHHHTT....TCEESSSSEEEEGGGGGSTTTBCSSSB--TTEEEEEEEEEEETTEEEEE CS
  Peptidase_M24   1 elirkaariasaaleavleaikpgvterelaaeieattlkrhg....arglafppivasgenaavlhytpndrvlkegdlvlidagaeydgyasDi 92 
                    e +rk++r+a+++l+ ++++ikpgvt++ ++++++++ l+r       +++ fp++v++++n+ ++h++p++r+l++gd+v+id++  + g+++D 
     EEA22005.1 138 EGMRKVCRLAREVLDIAAAEIKPGVTTDYIDEVVHKACLERDSypspLNYVHFPKSVCTSVNETICHGIPDQRPLQDGDIVNIDVTLYHGGFHGDL 233
                    57*************99999***************996666559999************************************************* PP

                    EEEEECS...SGSHHHHHHHHHHHHHHHHHHHC-STTSBHHHHHHHHHHHHHHTTBCCGBSSCSEEEESSSSSEEEEEESS..STTCSSB--TTBE CS
  Peptidase_M24  93 trTvlvG...kftpeqrelyeavleaqeaaikavkpGvtlseidaaarevlesaglakffphglGHgvGlevhdegpsvsr..esndgrkleeGmv 183
                      T++vG   k +p++ +++e+++e++++ i++vkpG+ +++ +++++++++s++  ++++ ++GHg+ + +h   p++++  ++++    ++Gm+
     EEA22005.1 234 NETYYVGdkaKASPDAVRVVETARECLDQSIALVKPGMLFRDPGNVIEKHAKSRNC-SVVKSYCGHGINQLFHCA-PNIPHyaKNKTVGAAKPGMC 327
                    *******88888888999***********************************999.999*************98.*99886444467779***** PP

                    EEEEEEEE.......EETTT...........E.EEEEBEEEEEES CS
  Peptidase_M24 184 ftiEpgiy.......fapge...........g.gvriedtvlvte 209
                    ftiEp+i        +   +           + ++++e+t+lvte
     EEA22005.1 328 FTIEPMINlgthkdkT---WpddwtsvtadgSlSAQFEHTLLVTE 369
                    *****77755433221...24444777888766***********7 PP

>> zf-C6H2  zf-MYND-like zinc finger, mRNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.9   7.3   3.5e-23   1.6e-19       1      46 [.       9      53 ..       9      54 .. 0.97

  Alignments for each domain:
  == domain 1  score: 69.9 bits;  conditional E-value: 3.5e-23
     zf-C6H2  1 CasseCgkeassLqCptClklgikesfFCsqeCFkknwkkHkalHk 46
                C++ +C ++a++LqCptClk+g++ sfFCsq+CFk++w++Hk++Hk
  EEA22005.1  9 CSGLDCANDAGTLQCPTCLKMGTD-SFFCSQDCFKRSWASHKTVHK 53
                9*********************77.********************8 PP

>> zf-MYND  MYND finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   5.2   1.4e-07   0.00062       4      37 ..      14      51 ..       7      52 .. 0.79
   2 ?   -1.2   0.2      0.49   2.2e+03      14      23 ..     287     297 ..     280     299 .. 0.68

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 1.4e-07
                T--.B-SC.E-TTTS-S....EESSHHHHHHCHHHHCCC CS
     zf-MYND  4 Cgkaealk.kCagCksv....fYCskeCqradwksHkte 37
                C + +a + +C+ C +     f+Cs++C ++ w sHkt 
  EEA22005.1 14 CAN-DAGTlQCPTCLKMgtdsFFCSQDCFKRSWASHKTV 51
                666.55556*****6555555****************96 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.49
                 TTTS-S.EESS CS
     zf-MYND  14 agCksv.fYCs 23 
                  +C+ v  YC+
  EEA22005.1 287 RNCSVVkSYCG 297
                 56877757997 PP

>> zf-HIT  HIT zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   3.3   0.00013      0.57       4      30 .]       8      42 ..       5      42 .. 0.94

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00013
                B-TT..T-S.B-SEE-TTT--E.....ESSHHHHH CS
      zf-HIT  4 lCgv..Cgf.pakYkCpkCntr.....yCSLrCyk 30
                +C+   C +  +   Cp+C  +     +CS +C+k
  EEA22005.1  8 KCSGldCANdAGTLQCPTCLKMgtdsfFCSQDCFK 42
                799999***************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (399 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       489  (0.0272742); expected 358.6 (0.02)
Passed bias filter:                      382  (0.0213063); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.49u 0.24s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2861.52
//
Query:       EEA22006.1  [L=381]
Description: methionine aminopeptidase, type I, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.1e-47  162.5   0.0    1.3e-47  162.2   0.0    1.1  1  Peptidase_M24  Metallopeptidase family M24
    6.2e-20   71.2   7.3    1.5e-19   70.0   7.3    1.7  1  zf-C6H2        zf-MYND-like zinc finger, mRNA-binding
    0.00058   19.9   5.2    0.00058   19.9   5.2    2.3  2  zf-MYND        MYND finger
  ------ inclusion threshold ------
       0.22   11.4   3.3       0.54   10.2   3.3    1.7  1  zf-HIT         HIT zinc finger


Domain annotation for each model (and alignments):
>> Peptidase_M24  Metallopeptidase family M24
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  162.2   0.0   2.9e-51   1.3e-47       1     209 []     120     351 ..     120     351 .. 0.89

  Alignments for each domain:
  == domain 1  score: 162.2 bits;  conditional E-value: 2.9e-51
                    HHHHHHHHHHHHHHHHHHHHHHTTCBHHHHHHHHHHHHHHHTT....TCEESSSSEEEEGGGGGSTTTBCSSSB--TTEEEEEEEEEEETTEEEEE CS
  Peptidase_M24   1 elirkaariasaaleavleaikpgvterelaaeieattlkrhg....arglafppivasgenaavlhytpndrvlkegdlvlidagaeydgyasDi 92 
                    e +rk++r+a+++l+ ++++ikpgvt++ ++++++++ l+r       +++ fp++v++++n+ ++h++p++r+l++gd+v+id++  + g+++D 
     EEA22006.1 120 EGMRKVCRLAREVLDIAAAEIKPGVTTDYIDEVVHKACLERDSypspLNYVHFPKSVCTSVNETICHGIPDQRPLQDGDIVNIDVTLYHGGFHGDL 215
                    57*************99999***************996666559999************************************************* PP

                    EEEEECS...SGSHHHHHHHHHHHHHHHHHHHC-STTSBHHHHHHHHHHHHHHTTBCCGBSSCSEEEESSSSSEEEEEESS..STTCSSB--TTBE CS
  Peptidase_M24  93 trTvlvG...kftpeqrelyeavleaqeaaikavkpGvtlseidaaarevlesaglakffphglGHgvGlevhdegpsvsr..esndgrkleeGmv 183
                      T++vG   k +p++ +++e+++e++++ i++vkpG+ +++ +++++++++s++  ++++ ++GHg+ + +h   p++++  ++++    ++Gm+
     EEA22006.1 216 NETYYVGdkaKASPDAVRVVETARECLDQSIALVKPGMLFRDPGNVIEKHAKSRNC-SVVKSYCGHGINQLFHCA-PNIPHyaKNKTVGAAKPGMC 309
                    *******88888888999***********************************999.999*************98.*99886444467779***** PP

                    EEEEEEEE.......EETTT...........E.EEEEBEEEEEES CS
  Peptidase_M24 184 ftiEpgiy.......fapge...........g.gvriedtvlvte 209
                    ftiEp+i        +   +           + ++++e+t+lvte
     EEA22006.1 310 FTIEPMINlgthkdkT---WpddwtsvtadgSlSAQFEHTLLVTE 351
                    *****77755433221...24444777888766***********7 PP

>> zf-C6H2  zf-MYND-like zinc finger, mRNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.0   7.3   3.3e-23   1.5e-19       1      46 [.       9      53 ..       9      54 .. 0.97

  Alignments for each domain:
  == domain 1  score: 70.0 bits;  conditional E-value: 3.3e-23
     zf-C6H2  1 CasseCgkeassLqCptClklgikesfFCsqeCFkknwkkHkalHk 46
                C++ +C ++a++LqCptClk+g++ sfFCsq+CFk++w++Hk++Hk
  EEA22006.1  9 CSGLDCANDAGTLQCPTCLKMGTD-SFFCSQDCFKRSWASHKTVHK 53
                9*********************77.********************8 PP

>> zf-MYND  MYND finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   5.2   1.3e-07   0.00058       4      37 ..      14      51 ..       7      52 .. 0.79
   2 ?   -1.1   0.2      0.47   2.1e+03      14      23 ..     269     279 ..     262     281 .. 0.68

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 1.3e-07
                T--.B-SC.E-TTTS-S....EESSHHHHHHCHHHHCCC CS
     zf-MYND  4 Cgkaealk.kCagCksv....fYCskeCqradwksHkte 37
                C + +a + +C+ C +     f+Cs++C ++ w sHkt 
  EEA22006.1 14 CAN-DAGTlQCPTCLKMgtdsFFCSQDCFKRSWASHKTV 51
                666.55556*****6555555****************96 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.47
                 TTTS-S.EESS CS
     zf-MYND  14 agCksv.fYCs 23 
                  +C+ v  YC+
  EEA22006.1 269 RNCSVVkSYCG 279
                 56877757997 PP

>> zf-HIT  HIT zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   3.3   0.00012      0.54       4      30 .]       8      42 ..       5      42 .. 0.94

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00012
                B-TT..T-S.B-SEE-TTT--E.....ESSHHHHH CS
      zf-HIT  4 lCgv..Cgf.pakYkCpkCntr.....yCSLrCyk 30
                +C+   C +  +   Cp+C  +     +CS +C+k
  EEA22006.1  8 KCSGldCANdAGTLQCPTCLKMgtdsfFCSQDCFK 42
                799999***************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (381 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       441  (0.024597); expected 358.6 (0.02)
Passed bias filter:                      346  (0.0192983); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 2482.32
//
Query:       EEA22007.1  [L=545]
Description: MFS multidrug transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-45  156.0  58.9      2e-36  125.7  16.8    2.7  3  MFS_1         Major Facilitator Superfamily
    5.2e-14   52.0  10.9    5.2e-14   52.0  10.9    3.3  4  Sugar_tr      Sugar (and other) transporter
  ------ inclusion threshold ------
       0.12   12.2   0.0       0.19   11.6   0.0    1.2  1  NTP_transf_6  Nucleotidyltransferase


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  125.7  16.8   3.3e-40     2e-36       2     179 ..      61     236 ..      60     238 .. 0.96
   2 !   39.8  29.5   4.4e-14   2.6e-10     125     352 ..     248     460 ..     238     461 .. 0.78
   3 ?   -1.2   0.1      0.12   7.3e+02     150     172 ..     519     539 ..     509     544 .. 0.55

  Alignments for each domain:
  == domain 1  score: 125.7 bits;  conditional E-value: 3.3e-40
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgag 100
                 ++++fl+a++ +i+ +++   +++dl  +    ++++t y+l+   +++++G l + fGr+ +ll+++++f+ g+l++ +a+ +  l+++rv qG+g+g
  EEA22007.1  61 SIGVFLAAADQTIIVASYG-KIGSDLK-ALNLTSWIATSYFLTLTSFQPLYGKLCNIFGRKACLLFAYTVFGTGSLFCGLAQDINQLIAARVYQGIGGG 157
                 799****************.*******.**********************************************77777766666************** PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepper 179
                 ++++++ +li+d++p ++rg+  g++++ ++ G+ +g++lgg+la+++gWr++f++ a+++llaf+++++ll ++ p++
  EEA22007.1 158 GMTTVVSILISDLVPLRDRGLWQGIINIIYATGSGIGAPLGGILADYIGWRWAFIVQAPICLLAFLFVAFLLHVPGPDS 236
                 **********************************************************************999998876 PP

  == domain 2  score: 39.8 bits;  conditional E-value: 4.4e-14
       MFS_1 125 llsagfslGailgpllggllasslgWrav.fyilaivsllafvlfllllpeepperkrkspkeeekgtgpaplvpawkallkdpvlwillialllfffg 222
                 +l+a++ +Ga+lg  +g    s+++W+ +  yi  ivs+++fv   +l+ e+++++++++p  +               ++ ++    ll++ +++ff 
  EEA22007.1 248 FLGAMVLVGAVLGVSVGLDRGSNVSWTIPeTYISLIVSIVLFVA--FLVIENYVASEPFAPGHL---------------IFDQN----LLACYACNFFS 325
                 789999**********99999********************886..9************98888...............89999....66666666666 PP

       MFS_1 223 fsg...lltllplylqevlglsglllaglllallalvgailallagrlsdrlgr.rrrlllallllllaalglallavt..ssavllllvlvliGfglg 315
                 f+g   + +++ply+q v g s +  ag+ l    ++g+ ++l ag+l++r+g     ++++++lll+++l l+l++ +  + +  ++++ ++  fg g
  EEA22007.1 326 FAGfmgTIFYTPLYFQAVNGVS-ASVAGVRLLPQIILGVLGSLAAGYLMKRTGTyYGLTIFGYALLLAGSLVLFLFSGAiaDAYEGMIVGAMISAFGNG 423
                 666666****************.788888888888888888**********998444444444444555555555555575444444445555555777 PP

       MFS_1 316 fvfpsllalasdlappeeagtasglfntagslggalg 352
                 + +++ l  + ++a+ e ++ +++   +++slg++lg
  EEA22007.1 424 IGVTTTLIGLISNASSEDQAVVTACSYLFRSLGSVLG 460
                 7766666666666667*******************98 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 0.12
       MFS_1 150 Wravfyilaivsllafvlfllll 172
                    +f +  +++lla+v   +++
  EEA22007.1 519 TNITFAVQMGITLLALV--SAFF 539
                 34456666666666644..2333 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.0  10.9   8.7e-18   5.2e-14      47     191 ..      90     228 ..      39     254 .. 0.88
   2 ?   -1.4   0.1      0.13     8e+02     159     190 ..     263     294 ..     246     299 .. 0.56
   3 !    7.2   9.1   0.00032       1.9      56     153 ..     359     459 ..     313     471 .. 0.80
   4 ?   -1.6   0.0      0.16   9.5e+02     171     194 ..     520     543 ..     507     544 .. 0.77

  Alignments for each domain:
  == domain 1  score: 52.0 bits;  conditional E-value: 8.7e-18
                 HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHH CS
    Sugar_tr  47 lsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyql 145
                 l+++i+ ++++  +  + + g+l ++fGRk +ll+a ++f  g++ +++a+    + +li++Rv  Gig G+ +++v+++is + p + Rg   ++ + 
  EEA22007.1  90 LTSWIATSYFLTLTSFQPLYGKLCNIFGRKACLLFAYTVFGTGSLFCGLAQ---DINQLIAARVYQGIGGGGMTTVVSILISDLVPLRDRGLWQGIINI 185
                 56777777777777777889*******************************...9******************************************** PP

                 HHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS CS
    Sugar_tr 146 aitfGilvaaifglglnktsnadgwrillglqlvpallllilllfl 191
                  +++G  ++a +g +l+++ +   wr+ + +q+ + ll ++++ fl
  EEA22007.1 186 IYATGSGIGAPLGGILADYIG---WRWAFIVQAPICLLAFLFVAFL 228
                 ******************999...**********999999999887 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.13
                 HHHHTSS-TTHHHHH.HHCCHHHHHHHHHHGGG CS
    Sugar_tr 159 lglnktsnadgwril.lglqlvpallllilllf 190
                 +gl++ sn + w i+  +++l+ +++l++++l+
  EEA22007.1 263 VGLDRGSN-VSWTIPeTYISLIVSIVLFVAFLV 294
                 33355555.667776345566666666665555 PP

  == domain 3  score: 7.2 bits;  conditional E-value: 0.00032
                 HHHHHHHHHHHHHHHHHTTHHHHHHH.HHHHHHHHHHHHH-TTTT..SS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHH CS
    Sugar_tr  56 lvGaiiGslfagllgdrfGRkkslli.aavlfvigavlqaaakgk..nsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGi 151
                 ++ +++Gsl ag+l++r G  ++l i + +l+++g+++ ++  g+   ++e +ivg +++ +g G+  +++ + +  +A  +    ++ +  l+ ++G 
  EEA22007.1 359 IILGVLGSLAAGYLMKRTGTYYGLTIfGYALLLAGSLVLFLFSGAiaDAYEGMIVGAMISAFGNGIGVTTTLIGLISNASSEDQAVVTACSYLFRSLGS 457
                 567899***************999775889999999999988888899*****************9988876666666665555555555555555555 PP

                 HH CS
    Sugar_tr 152 lv 153
                 ++
  EEA22007.1 458 VL 459
                 55 PP

  == domain 4  score: -1.6 bits;  conditional E-value: 0.16
                 HHHHHCCHHHHHHHHHHGGGS--- CS
    Sugar_tr 171 rillglqlvpallllilllflPES 194
                  i++++q+ ++ll l+  +f+ E+
  EEA22007.1 520 NITFAVQMGITLLALVSAFFIKET 543
                 688999999999999999999887 PP

>> NTP_transf_6  Nucleotidyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   3.2e-05      0.19      68     120 ..      27      79 ..       5      93 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 3.2e-05
  NTP_transf_6  68 pwevkNqarmhlwnedepytstedAiskwpetatavGvrleeegeleliapfG 120
                   p +v N a++ + n+ ++ +s++ +  +++  a  +Gv l + ++  ++a +G
    EEA22007.1  27 PEQVSNDASLPQENGAQKGSSSTSSQLRYVVPAISIGVFLAAADQTIIVASYG 79 
                   568*************************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (545 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       608  (0.0339115); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.61u 0.29s 00:00:00.89 Elapsed: 00:00:00.45
# Mc/sec: 3621.70
//
Query:       EEA22008.1  [L=998]
Description: EF hand domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.8e-12   45.9   8.1    5.1e-05   22.5   1.0    3.7  3  EF-hand_1       EF hand
    3.5e-11   42.7   6.4    5.8e-11   42.0   6.4    1.3  1  ZZ              Zinc finger, ZZ type
    2.7e-10   39.3   5.4    3.2e-05   23.5   0.2    3.7  3  EF-hand_6       EF-hand domain
      1e-09   38.7   0.6    8.8e-05   22.9   0.1    3.5  3  EF-hand_7       EF-hand domain pair
    0.00036   19.9   6.7       0.23   11.0   0.6    3.3  3  EF-hand_5       EF hand
     0.0014   18.9   4.5     0.0027   18.0   4.5    1.4  1  C1_2            C1 domain
     0.0048   16.7   5.4       0.31   10.9   0.5    3.4  3  EF-hand_8       EF-hand domain pair
  ------ inclusion threshold ------
      0.045   14.0   0.1        0.2   11.9   0.0    2.1  2  Dockerin_1      Dockerin type I domain
       0.54    8.3   3.4        1.1    7.2   3.4    1.4  1  Sporozoite_P67  Sporozoite P67 surface antigen


Domain annotation for each model (and alignments):
>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5   1.0   2.5e-08   5.1e-05       2      28 ..     408     434 ..     407     435 .. 0.92
   2 !   22.0   0.4   3.7e-08   7.3e-05       2      28 ..     444     470 ..     443     471 .. 0.93
   3 ?    3.7   0.0     0.026        53      16      27 ..     968     979 ..     968     981 .. 0.89

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 2.5e-08
                 HHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1   2 lkeiFrefDkDgdGkIdfeEfkellkk 28 
                 ++++F+ +D++gd  I feEf++ +++
  EEA22008.1 408 FDRMFAFYDTNGDNLIGFEEFVKGIAS 434
                 89********************98865 PP

  == domain 2  score: 22.0 bits;  conditional E-value: 3.7e-08
                 HHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1   2 lkeiFrefDkDgdGkIdfeEfkellkk 28 
                 +++iF+ +D++gdG++++++f++++++
  EEA22008.1 444 MRRIFKGYDVNGDGFVERKDFLRMFRA 470
                 689*********************986 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.026
                 EEEHHHHHHHHH CS
   EF-hand_1  16 kIdfeEfkellk 27 
                 k++++Ef+++++
  EEA22008.1 968 KLSYDEFRRIMN 979
                 79********97 PP

>> ZZ  Zinc finger, ZZ type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.0   6.4   2.9e-14   5.8e-11       1      41 [.     262     302 ..     262     306 .. 0.90

  Alignments for each domain:
  == domain 1  score: 42.0 bits;  conditional E-value: 2.9e-14
                 -SS-EE-TTT-S..EESSEEEESSSSS-EE-HHHHHH.H-- CS
          ZZ   1 ihkkytCdgCseapligvRyhclrcsdYDLCqsCfsthkag 41 
                 ih ++tC+ C+  p+ g Ry+c  c d+DLC +C+ ++++ 
  EEA22008.1 262 IHRGVTCNNCGMMPIQGIRYRCDNCVDFDLCENCEAQQVHN 302
                 6999*******************************995544 PP

>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.8   0.7     2e-05     0.041       2      26 ..     408     432 ..     408     436 .. 0.89
   2 !   23.5   0.2   1.6e-08   3.2e-05       1      27 [.     443     469 ..     443     476 .. 0.94
   3 ?    1.4   0.0       0.2   3.9e+02      16      28 ..     968     980 ..     964     987 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2e-05
   EF-hand_6   2 lreaFklfDkdgdGkidaeElrkal 26 
                 +++ F  +D++gd+ i +eE++k +
  EEA22008.1 408 FDRMFAFYDTNGDNLIGFEEFVKGI 432
                 5789*****************9976 PP

  == domain 2  score: 23.5 bits;  conditional E-value: 1.6e-08
   EF-hand_6   1 elreaFklfDkdgdGkidaeElrkalr 27 
                 ++r++Fk +D++gdG++ ++++ +++r
  EEA22008.1 443 KMRRIFKGYDVNGDGFVERKDFLRMFR 469
                 69***********************99 PP

  == domain 3  score: 1.4 bits;  conditional E-value: 0.2
   EF-hand_6  16 kidaeElrkalrk 28 
                 k++++E+r+++++
  EEA22008.1 968 KLSYDEFRRIMNT 980
                 79*********96 PP

>> EF-hand_7  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.6   0.0    0.0003       0.6      46      68 ..     408     430 ..     384     433 .. 0.79
   2 !   22.9   0.1   4.4e-08   8.8e-05       1      49 [.     441     486 ..     441     495 .. 0.86
   3 ?    0.6   0.0      0.39   7.8e+02      60      70 ..     968     978 ..     957     979 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.0003
   EF-hand_7  46 lellfkefDtdkdGvisfdEFlk 68 
                  +++f   Dt++d  i f+EF+k
  EEA22008.1 408 FDRMFAFYDTNGDNLIGFEEFVK 430
                 45666667*************87 PP

  == domain 2  score: 22.9 bits;  conditional E-value: 4.4e-08
   EF-hand_7   1 eeklkeaFkelDtdgdgyldkeellrllrkifqgagegsklsdeelell 49 
                 +ek++++Fk +D++gdg++++ ++lr++r+ +      ++ls + ++++
  EEA22008.1 441 DEKMRRIFKGYDVNGDGFVERKDFLRMFRAYY---ALIKELSADLVQAW 486
                 5899*******************999***988...77777777777777 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.39
   EF-hand_7  60 visfdEFlkly 70 
                 ++s+dEF++++
  EEA22008.1 968 KLSYDEFRRIM 978
                 89*****9998 PP

>> EF-hand_5  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.6   0.00012      0.23       2      21 ..     409     428 ..     408     432 .. 0.88
   2 !   10.3   0.2   0.00019      0.38       4      24 ..     447     467 ..     444     468 .. 0.83
   3 ?   -0.4   0.0      0.47   9.4e+02      15      25 .]     968     978 ..     968     978 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00012
                 HHHHHHH-SS-SSCE-HHHH CS
   EF-hand_5   2 kdtFqaiDlNgDGkIskeEL 21 
                 + +F   D+NgD  I +eE+
  EEA22008.1 409 DRMFAFYDTNGDNLIGFEEF 428
                 4589***************9 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00019
                 HHHHH-SS-SSCE-HHHHHHH CS
   EF-hand_5   4 tFqaiDlNgDGkIskeELktl 24 
                  F+  D+NgDG++ +  + ++
  EEA22008.1 447 IFKGYDVNGDGFVERKDFLRM 467
                 57778**********999775 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 0.47
                 CE-HHHHHHHH CS
   EF-hand_5  15 kIskeELktlv 25 
                 k+s +E+++++
  EEA22008.1 968 KLSYDEFRRIM 978
                 799*****976 PP

>> C1_2  C1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   4.5   1.4e-06    0.0027      18      46 ..     265     295 ..     246     296 .. 0.90

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 1.4e-06
        C1_2  18 sfnCsaCgrk.idgffYsCseC.dfslhvrC 46 
                   +C+ Cg   i+g +Y+C+ C df l+++C
  EEA22008.1 265 GVTCNNCGMMpIQGIRYRCDNCvDFDLCENC 295
                 479******99***********9******** PP

>> EF-hand_8  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.9   0.5   0.00016      0.31      31      50 ..     411     430 ..     408     434 .. 0.89
   2 !    5.3   0.2     0.009        18      26      53 ..     442     469 ..     435     471 .. 0.90
   3 ?    0.6   0.0      0.26   5.1e+02       3      16 ..     967     981 ..     965     987 .. 0.72

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00016
   EF-hand_8  31 lfrefDtdgdGkisfeEFcv 50 
                 +f   Dt+gd+ i+feEF+ 
  EEA22008.1 411 MFAFYDTNGDNLIGFEEFVK 430
                 89999*************85 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.009
   EF-hand_8  26 eevdilfrefDtdgdGkisfeEFcvlle 53 
                 e+++ +f+  D +gdG +  ++F+ ++ 
  EEA22008.1 442 EKMRRIFKGYDVNGDGFVERKDFLRMFR 469
                 678889******************9986 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.26
   EF-hand_8   3 gkItreelrril.ri 16 
                  k++ +e+rri+ + 
  EEA22008.1 967 AKLSYDEFRRIMnTD 981
                 678889999999554 PP

>> Dockerin_1  Dockerin type I domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       3.1   6.2e+03      35      43 ..     413     421 ..     410     423 .. 0.77
   2 ?   11.9   0.0    0.0001       0.2      36      53 ..     450     467 ..     435     470 .. 0.83

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 3.1
                 GGGSTT-SS CS
  Dockerin_1  35 kaaDvNgDG 43 
                 +++D NgD+
  EEA22008.1 413 AFYDTNGDN 421
                 578999986 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 0.0001
                 GGSTT-SSCESHHHHHHH CS
  Dockerin_1  36 aaDvNgDGrvnalDallv 53 
                  +DvNgDG v   D+l++
  EEA22008.1 450 GYDVNGDGFVERKDFLRM 467
                 699999999999999987 PP

>> Sporozoite_P67  Sporozoite P67 surface antigen
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   3.4   0.00056       1.1      78     138 ..     557     635 ..     549     642 .. 0.71

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.00056
  Sporozoite_P67  78 tpvseeiitrsfqep...............vsqeselqsdteineddk...Gskedseedddeeeeednkstsskdgkg 138
                     t v+e  + r f+++               vs  +e++ +++ +e+++    + + +e+d++  +eed+++t s  +  
      EEA22008.1 557 TAVAESAVRRQFRQRqdlpnihpdvsppssVSGGVEVEGEAQAEEEGEqaqPEATAEEDDNEGTDEEDDEATGSTAEEV 635
                     77888888888887778888888888888855555555555555444300044567788888899*******9987765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (998 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       917  (0.0511462); expected 358.6 (0.02)
Passed bias filter:                      594  (0.0331307); expected 358.6 (0.02)
Passed Vit filter:                        73  (0.00407162); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.84u 0.30s 00:00:01.13 Elapsed: 00:00:00.47
# Mc/sec: 6434.63
//
Query:       EEA22009.1  [L=325]
Description: NAD dependent epimerase/dehydratase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.9e-08   33.1   0.0     0.0018   17.8   0.0    2.2  2  Epimerase       NAD dependent epimerase/dehydratase family
     0.0059   15.8   0.0       0.01   15.1   0.0    1.3  1  NAD_binding_4   Male sterility protein
  ------ inclusion threshold ------
      0.019   14.8   0.0      0.038   13.9   0.0    1.5  2  NAD_binding_10  NAD(P)H-binding
       0.13   12.7   0.0        0.3   11.5   0.0    1.6  2  Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domai
        0.2   11.2   0.0        0.3   10.6   0.0    1.3  1  NmrA            NmrA-like family


Domain annotation for each model (and alignments):
>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   4.9e-07    0.0018       1      71 [.       5      80 ..       5      86 .. 0.82
   2 !   13.2   0.0   1.3e-05     0.046     158     229 ..     143     214 ..     133     224 .. 0.86

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 4.9e-07
                EEEETTTSHHHHHHHHHHHHCT...SE.EEEEES-STTTTCHHCHHC...EEEE--TT-HHHHHHHHHHHT-SEEEE- CS
   Epimerase  1 ilVtGatGfiGsalvkallekg...ye.vigldrlssasntarledl...elveldltdrsalerlfkeeqpdavihl 71
                il+tGa+G++G  l+ +++e++   y+ + +l r +++ n  +   l   e v++dl+ ++++e+++ + ++ +++ l
  EEA22009.1  5 ILITGASGYLGGTLLTRWKEANlppYNkLYALIRTEEQANAVQT--LynaEPVQIDLRSDVDIEQAIISRDISIIYYL 80
                8*********************9996667777777555444332..23469**************9998888888865 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 1.3e-05
                 HHHT-EEEEEEESEEESTTS-TTS.TTSHHHHHHHHHHTTSSSEEEETTST-EEEEEEHHHHHHHHHHHHHHH CS
   Epimerase 158 aqyglnaiilrlfnlyGprngege.vsrvipalirkilegkqevtllgdgtalRdflyveDvaeaillvlehv 229
                 a++g++  i+ ++ +yG+++g g+  s    a+ir +++ + ++  ++d +a+++ ++++D  +++l +l+  
  EEA22009.1 143 ASFGVRSYIFAPCIVYGKGQGFGNpISIQTVAVIRAAKKMR-KIYTVDDSSARWPVCHIDDNTTLFLSILRDI 214
                 7889999************7777767777788888888888.********************99999999875 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   2.8e-06      0.01       1      41 [.       7      49 ..       7      71 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 2.8e-06
                   EE-TTSHHHHHHHHHHHHHS.-.T.EEEEEE-SSSHHHHHHHH CS
  NAD_binding_4  1 lTGaTGFLGkvLlekLLrtt.pev.kiyllvRaksgesaeeRl 41
                   +TGa+G+LG  Ll ++ + + p + k+y+l+R++++++a + l
     EEA22009.1  7 ITGASGYLGGTLLTRWKEANlPPYnKLYALIRTEEQANAVQTL 49
                   8***************865524458***********9998877 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   1.1e-05     0.038       1      63 [.       9      74 ..       9      94 .. 0.90
   2 ?   -3.8   0.0       2.9     1e+04      21      33 ..     171     183 ..     163     188 .. 0.68

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.1e-05
                    TTTSHHHHHHHHHHHHC-...T-EEEEEETTHHHCHHHHCTTTCEEEE--TT-CCHHHHHHTT-SE CS
  NAD_binding_10  1 GAtGkvGrllvkellarg...ghevtalvRnpeklaeleaeeglevvegdvtdvedlaealkgada 63
                    GA+G  G  l+++  +++     ++ al+R++e++++++   ++e v++d+ +  d+++a+   d+
      EEA22009.1  9 GASGYLGGTLLTRWKEANlppYNKLYALIRTEEQANAVQTLYNAEPVQIDLRSDVDIEQAIISRDI 74
                    99************999988766799************988*******************987775 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 2.9
                     EEEEEETTHHHCH CS
  NAD_binding_10  21 evtalvRnpekla 33 
                     +++a++R ++k+ 
      EEA22009.1 171 QTVAVIRAAKKMR 183
                     5566666666665 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   8.4e-05       0.3       2      58 ..       5      63 ..       4      78 .. 0.73
   2 ?   -4.0   0.0         5   1.8e+04      88     100 ..     133     145 ..     128     154 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 8.4e-05
                    EEEETTTSHHHHHHHHHHHC..TSSEEEEEEEESTTTTTSBHHHHSGGGTTTECEBEEE CS
  Semialdhyde_dh  2 vaivGatGyvGqellrlLee..hpevelvvllsssrsaGkklaeavkaleegkdlkved 58
                    + i Ga+Gy G  ll++ +e   p+++ +++l +++++ ++++ +++a   + dl+ + 
      EEA22009.1  5 ILITGASGYLGGTLLTRWKEanLPPYNKLYALIRTEEQANAVQTLYNAEPVQIDLRSDV 63
                    7899***************9987889999888888889999999988444444443333 PP

  == domain 2  score: -4.0 bits;  conditional E-value: 5
                     HTTSEEEESSSTT CS
  Semialdhyde_dh  88 eagvkviDlssdf 100
                     +++v+viD  + f
      EEA22009.1 133 KRNVQVIDDGASF 145
                     6678888877766 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   8.5e-05       0.3       1      68 [.       5      75 ..       5      88 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 8.5e-05
                EEESSTTSHHHHHHHHHHHH....HT-EEEEEES-S.-SHHHHHHHHSTTEEEES-TT-HHHHHHHHTT-SEE CS
        NmrA  1 IlviGaTGrqGksvvrallk....aghkvralvRdt.kselakslkeaGvelvkgdlddkeslvealkgvdvv 68
                Il++Ga+G++G+ +     +      +k  al+R + + +++++l +  +e v+ dl ++  +++a+   d  
  EEA22009.1  5 ILITGASGYLGGTLLTRWKEanlpPYNKLYALIRTEeQANAVQTLYN--AEPVQIDLRSDVDIEQAIISRDIS 75
                89************98888844446689******8845566777766..578888998888888888666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (325 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       403  (0.0224776); expected 358.6 (0.02)
Passed bias filter:                      396  (0.0220871); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.50u 0.22s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2369.58
//
Query:       EEA22010.1  [L=433]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.4e-163  544.5   0.0   1.6e-163  544.3   0.0    1.0  1  DUF1688   Protein of unknown function (DUF1688)


Domain annotation for each model (and alignments):
>> DUF1688  Protein of unknown function (DUF1688)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  544.3   0.0  8.9e-168  1.6e-163       1     422 []       7     433 .]       7     433 .] 0.97

  Alignments for each domain:
  == domain 1  score: 544.3 bits;  conditional E-value: 8.9e-168
     DUF1688   1 yLrslkavRerckkvlelakegklehfdvdeskleevadfvvkvikrdygp.dlksiPphgRwrHfevggvdriaelleklkkek.delekarrliDLf 97 
                 y++slkavRe+++kvlela++gkl+hf+++++kl+ +ad+v+++i+rd+gp +++ iPphgRw+Hfevgg +ri++ll++++ +  d++e++r l+DLf
  EEA22010.1   7 YILSLKAVREQAHKVLELAEQGKLTHFNYHHEKLSVAADYVIELIQRDFGPdKYNLIPPHGRWQHFEVGGLPRIESLLSQWEGKGyDNVERVRGLVDLF 105
                 789***********************************************98999***************************8889************* PP

     DUF1688  98 lvsvLLDagagekwkykekesgekykrseGlavaslemFkaglfss.deeeklrvdaegLkkltaeklakalqvseenplvGlegRaelLkrLgealee 195
                 +vsvLLDagag+ wk++e+ s+++y+rseG+a asl+mF +g f+s  +++k  v+a++L+  +aek+ +++q++++npl  ++ R+elL+rLg++l +
  EEA22010.1 106 FVSVLLDAGAGDVWKFQEPGSEQTYNRSEGIANASLHMFLNGDFASeGSSRKDIVEAAALRLPHAEKFYRGFQIQKTNPLLAVDKRMELLRRLGDSLLN 204
                 *********************************************956889999********************************************* PP

     DUF1688 196 kpevfgeegrpgnlvdyllskakekasskkeveleelwevlleglapiWpasrtkidgvslGDvWplsalkks....keeeeeslvpfHkLsqWltYSL 290
                  pe+fg++grpg+lvdyllska    s + e+++ elw+vl+++l+piWp++rt++dg+++GD+Wpl+ l+ks    +++++++++pfHkL+qWl+YSL
  EEA22010.1 205 FPEIFGANGRPGHLVDYLLSKA----SGSGEIDYIELWSVLQKVLIPIWPSDRTHVDGHAVGDAWPLTCLAKSsdpnTSNKTSAIQPFHKLTQWLAYSL 299
                 *******************777....7899****************************************985666689999***************** PP

     DUF1688 291 leplekllglkvegleeltgLpeYrNGGLlvDlgvltlkkealerglkksee..elpafeasdevivewRalTvalLDelaeevreklelsaeeLsLaq 387
                 ++p+++ll++++ + ++ tgL+eYrNGGL+vD+gvltlk+e+l+rgl+ s++   lp f asd+ ivewRalTvalLD+l++ ++++ + +  +L+L+q
  EEA22010.1 300 MVPFTRLLDITWVNPDQGTGLAEYRNGGLFVDMGVLTLKEESLARGLQGSSNddGLPCFGASDDEIVEWRALTVALLDKLHDIIKSSPRFNGVQLTLPQ 398
                 ***********************************************977765589******************************************* PP

     DUF1688 388 vLeagtWkaGReiAkekrpetkepPieiesDgtvF 422
                 vLeag+WkaGRe+A+ekrp tk++Pi i  Dgt+F
  EEA22010.1 399 VLEAGSWKAGRELAAEKRPLTKSSPIIILGDGTLF 433
                 *********************************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (433 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       217  (0.0121033); expected 358.6 (0.02)
Passed bias filter:                      216  (0.0120475); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 2873.28
//
Query:       EEA22011.1  [L=377]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.21   12.2   0.0        7.7    7.2   0.0    2.4  2  RbpA      RNA polymerase-binding protein


Domain annotation for each model (and alignments):
>> RbpA  RNA polymerase-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0     0.015   2.7e+02      76      89 ..     228     241 ..     225     251 .. 0.87
   2 ?    7.2   0.0   0.00043       7.7      65      84 ..     301     320 ..     284     334 .. 0.72

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.015
        RbpA  76 yrtHldmlkERRse 89 
                 y+t l +l+ERR e
  EEA22011.1 228 YKTTLTHLLERRDE 241
                 89**********86 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.00043
        RbpA  65 eepeeekkekpyrtHldmlk 84 
                 ++++++++  + rtH+d+l 
  EEA22011.1 301 HNDNNNERIGQRRTHWDYLE 320
                 344467788899******86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (377 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       497  (0.0277205); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.24s 00:00:00.70 Elapsed: 00:00:00.41
# Mc/sec: 2782.02
//
Query:       EEA22012.1  [L=576]
Description: mRNA splicing factor (Prp17), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.1e-30  105.2   6.2    3.3e-07   30.9   0.0    7.0  7  WD40         WD domain, G-beta repeat
    2.5e-16   59.7   0.0      1e-05   25.7   0.0    4.7  4  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
    2.2e-05   24.2   0.0    5.8e-05   22.8   0.0    1.7  1  PQQ_2        PQQ-like domain
  ------ inclusion threshold ------
      0.018   15.0   0.3       0.26   11.3   0.0    2.9  3  PD40         WD40-like Beta Propeller Repeat
      0.032   14.1   0.2        2.3    8.1   0.0    3.0  3  eIF2A        Eukaryotic translation initiation factor eIF2A
       0.11   11.6   0.1       0.46    9.5   0.0    2.0  3  DUF1513      Protein of unknown function (DUF1513)
       0.13   11.1   0.8         15    4.4   0.0    3.1  3  Ge1_WD40     WD40 region of Ge1, enhancer of mRNA-decapping p


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.1   2.3e-08   5.9e-05       2      38 .]     273     311 ..     272     311 .. 0.92
   2 !   30.9   0.0   1.3e-10   3.3e-07       2      38 .]     317     354 ..     316     354 .. 0.96
   3 ?    2.3   0.0      0.14   3.7e+02      12      38 .]     370     398 ..     358     398 .. 0.60
   4 !   11.7   0.0   0.00015      0.38       2      37 ..     403     439 ..     402     440 .. 0.85
   5 ?   -0.4   0.0      0.98   2.5e+03      17      36 ..     462     481 ..     456     482 .. 0.74
   6 !   20.9   0.1   1.9e-07   0.00048       6      38 .]     495     530 ..     489     530 .. 0.84
   7 !   11.7   0.0   0.00015      0.39      12      38 .]     546     576 .]     534     576 .] 0.82

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 2.3e-08
                 EEEEEEESS.SSEEEEE.EETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtsla.fspdgawlasGsdDgtvriWd 38 
                 +++++++ H +++tsl+ f++ g++l+s+  Dg+ +iWd
  EEA22012.1 273 KLVHSWKSHtKPITSLRfFPKFGHLLLSSAADGKAKIWD 311
                 789******999*****99999999999988*******9 PP

  == domain 2  score: 30.9 bits;  conditional E-value: 1.3e-10
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 ++lrt++GH +s+++  f+p g+ ++++s+D+ +++Wd
  EEA22012.1 317 ELLRTYSGHsKSISDTTFHPTGKTFLTASYDRQIKLWD 354
                 789******999*************************9 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.14
                 S.EEEEEEETTSSE.EEEEETTSEEEEEE CS
        WD40  12 s.vtslafspdgaw.lasGsdDgtvriWd 38 
                 + v  +  +p+++  +++G+ D+++  +d
  EEA22012.1 370 PhVVRINPDPEHNHeFLAGMSDKKIVQFD 398
                 237788766666667557*6699998766 PP

  == domain 4  score: 11.7 bits;  conditional E-value: 0.00015
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriW 37 
                 + +++++ H   v+ + f ++++ +++ sdD+++r W
  EEA22012.1 403 EMVQEYDHHlAAVNTITFVDNNRRFITTSDDKSLRAW 439
                 567899999999999998888888888999*****99 PP

  == domain 5  score: -0.4 bits;  conditional E-value: 0.98
                 EEETTSSEEE..EEETTSEEEE CS
        WD40  17 afspdgawla..sGsdDgtvri 36 
                 a +p+g+++a  sG  D+ + +
  EEA22012.1 462 APHPSGKYVAfqSG--DNQIVV 481
                 579*****976665..776665 PP

  == domain 6  score: 20.9 bits;  conditional E-value: 1.9e-07
                 EEESSSS....EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   6 tltGHss....vtslafspdgawlasGsdDgtvriWd 38 
                  ++GH+     + ++afspdg++lasG+  g   +Wd
  EEA22012.1 495 GFRGHNTagyaI-DIAFSPDGQFLASGDSGGYACFWD 530
                 499**4457999.**************6699999998 PP

  == domain 7  score: 11.7 bits;  conditional E-value: 0.00015
                 S...EEEEEEETTSSE.EEEEETTSEEEEEE CS
        WD40  12 s...vtslafspdgaw.lasGsdDgtvriWd 38 
                 +   vt+l+++p  +  +++G+  g ++ Wd
  EEA22012.1 546 DglaVTCLDWHPQETSkVVTGGLEGVIKYWD 576
                 34669***99999999878***********9 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.2   0.0   0.00028      0.72      35      73 ..     279     318 ..     270     329 .. 0.78
   2 !   14.0   0.0   1.8e-05     0.047      36      85 ..     324     373 ..     317     376 .. 0.89
   3 ?    4.5   0.0     0.016        41      53      90 ..     385     421 ..     380     423 .. 0.83
   4 !   25.7   0.0     4e-09     1e-05      22      90 ..     488     556 ..     465     558 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00028
  ANAPC4_WD40  35 dkedsevrsLaWkpd.gklLavaysdgevrlldaesgkvv 73 
                  +++ + ++sL++ p+ g+lL  + +dg+ ++ d+++++ +
   EEA22012.1 279 KSHTKPITSLRFFPKfGHLLLSSAADGKAKIWDVYHQREL 318
                  567899****998866******************987544 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 1.8e-05
  ANAPC4_WD40  36 kedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavt 85 
                  ++++++++  ++p gk +  a  d +++l d e gk+++ +s++++ +v+
   EEA22012.1 324 GHSKSISDTTFHPTGKTFLTASYDRQIKLWDTEYGKCISRFSTGKTPHVV 373
                  577899999*********************************99987665 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.016
  ANAPC4_WD40  53 LavaysdgevrlldaesgkvvhslsvksekavtclgWg 90 
                  +  ++sd ++  +d  +g++v++++ +   av+++++ 
   EEA22012.1 385 FLAGMSDKKIVQFDTRTGEMVQEYDHHLA-AVNTITFV 421
                  45699*******************99988.58888876 PP

  == domain 4  score: 25.7 bits;  conditional E-value: 4e-09
  ANAPC4_WD40  22 fRlngqrvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksek..avtclgWg 90 
                  fR n ++ + +  +++ +   ++a++pdg++La + s g   + d ++gk+ h+l+++ ++  avtcl+W 
   EEA22012.1 488 FRQNRKKGFRG--HNTAGYAIDIAFSPDGQFLASGDSGGYACFWDWKTGKMYHKLQAGGKDglAVTCLDWH 556
                  68888888888..777888889***********************************988888*******7 PP

>> PQQ_2  PQQ-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8   0.0   2.3e-08   5.8e-05      14     200 ..     307     540 ..     295     568 .. 0.74

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 2.3e-08
       PQQ_2  14 aelWrvdlar........plgggvsravlsggtlfva.tgggrlvaldaatGkvlWettl...egpvvga.plvaegrvvvva.sdgqlialdaedGkr 98 
                 a++W v ++r         + +++++++++ g+ f + ++ +++  +d++ Gk + +++    +  v+ + p  + ++ +++  sd+ ++++d+++G+ 
  EEA22012.1 307 AKIWDVYHQRellrtysgHSKSISDTTFHPTGKTFLTaSYDRQIKLWDTEYGKCISRFSTgktPHVVR-InPDPEHNHEFLAGmSDKKIVQFDTRTGEM 404
                 678999665534444443378888888888776666659********************965333344.2699999999998889************** PP

       PQQ_2  99 .................................lWstqqrs.......eepaelrssaspavagdtvvvgessgklvaldpkdGkvlWerelaaprgts 157
                                                  +W+ +          e ++ +++ a+p  +g++v+++  ++++v++  ++ k + +r+ +      
  EEA22012.1 405 vqeydhhlaavntitfvdnnrrfittsddkslrAWE-YGIPvpikyiaEADMFAMVRAAPHPSGKYVAFQSGDNQIVVYA-ATDKFRQNRKKGF----- 496
                 99*******************999999999999999.7777555555335555666666666677777777777777776.4445555554433..... PP

       PQQ_2 158 elsrvgdisgrpvva.....egtVyassgqgrllal.dlatgrrlwske 200
                      g +++   ++     +g+ +as+ +g+ +++ d++tg+  + k 
  EEA22012.1 497 ----RGHNTAGYAIDiafspDGQFLASGDSGGYACFwDWKTGK-MYHKL 540
                 ....334444445555666779********************9.55444 PP

>> PD40  WD40-like Beta Propeller Repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0      0.85   2.2e+03      11      23 ..     329     341 ..     325     345 .. 0.81
   2 ?   -1.2   0.0      0.81   2.1e+03      18      27 ..     465     474 ..     462     476 .. 0.88
   3 ?   11.3   0.0    0.0001      0.26       6      24 ..     500     518 ..     500     518 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.85
                 EEEEEE-TTSSEE CS
        PD40  11 egaPsfSPDGkrl 23 
                 + + +f P Gk++
  EEA22012.1 329 ISDTTFHPTGKTF 341
                 56789******97 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.81
                 TTSSEEEEEE CS
        PD40  18 PDGkrlaFsS 27 
                 P Gk+ aF S
  EEA22012.1 465 PSGKYVAFQS 474
                 89******98 PP

  == domain 3  score: 11.3 bits;  conditional E-value: 0.0001
                 SSSS.EEEEEE-TTSSEEE CS
        PD40   6 ntpgnegaPsfSPDGkrla 24 
                 nt g+ ++++fSPDG+ la
  EEA22012.1 500 NTAGYAIDIAFSPDGQFLA 518
                 78899***********986 PP

>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.0    0.0009       2.3     112     164 ..     295     347 ..     274     357 .. 0.74
   2 ?    0.8   0.0      0.15   3.8e+02      77     115 ..     386     427 ..     379     471 .. 0.78
   3 ?    0.5   0.0      0.18   4.6e+02     105     154 ..     507     558 ..     487     568 .. 0.68

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0009
                 SSEEEEE-TTSSS-EEEEEETT.TTEEEEEE..E-TT--EEEE-TTSSEEEEEE-T CS
       eIF2A 112 gklvllaGfgnlaGeleiwdvk.kkkkiaka..eaanatlvewspdgryvlTatta 164
                 g+l+l +      G+ +iwdv  +++ + ++  +++  ++  ++p+g+ +lTa+  
  EEA22012.1 295 GHLLLSS---AADGKAKIWDVYhQRELLRTYsgHSKSISDTTFHPTGKTFLTASYD 347
                 5555544...3469999***9977777777622455668899***********865 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.15
                 EESSSSCEEEEEECS.CEEEEEEEEE..S--EEEE-TTSSEE CS
       eIF2A  77 iyGkmpakvslfdlk.vkviskleeq..krNtiffspkgklv 115
                 + G +++k++ fd++ ++++ +++++  + Nti f ++++ +
  EEA22012.1 386 LAGMSDKKIVQFDTRtGEMVQEYDHHlaAVNTITFVDNNRRF 427
                 579999999999997677777776642278999998776544 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.18
                 EEEE-TTSSEEEEE-TTSSS-EEEEEETTTTEEEEEEE-.....TT--EEEE-TT CS
       eIF2A 105 tiffspkgklvllaGfgnlaGeleiwdvkkkkkiakaea.....anatlvewspd 154
                  i fsp g++++ +  g   G   +wd k+ k ++k++a        t ++w+p+
  EEA22012.1 507 DIAFSPDGQFLASGDSG---GYACFWDWKTGKMYHKLQAggkdgLAVTCLDWHPQ 558
                 57788888888776554...55778888877777776552222234455577766 PP

>> DUF1513  Protein of unknown function (DUF1513)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       1.5   3.7e+03      73     109 ..     344     378 ..     317     382 .. 0.53
   2 ?   -1.6   0.0      0.44   1.1e+03       4      52 ..     379     427 ..     376     428 .. 0.79
   3 ?    9.5   0.0   0.00018      0.46     212     265 ..     498     550 ..     468     570 .. 0.81

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 1.5
     DUF1513  73 etgrGvigvydaaeglkkvaefstgGigpHellllad 109
                 ++    i ++d++  + k     + G  pH + + +d
  EEA22012.1 344 ASYDRQIKLWDTE--YGKCISRFSTGKTPHVVRINPD 378
                 3334456677766..5555555556777777766666 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.44
     DUF1513   4 peRaHgvaahpsdpeavavaRrPgtfllvldlesgeelqtlaaeedrhF 52 
                 pe  H+++a  sd+++v +  r g+++   d++ ++  + +  +++r F
  EEA22012.1 379 PEHNHEFLAGMSDKKIVQFDTRTGEMVQEYDHHLAAVNTITFVDNNRRF 427
                 5667999999999999999999999999888888777777777777766 PP

  == domain 3  score: 9.5 bits;  conditional E-value: 0.00018
     DUF1513 212 laalagYigsvavdsegrlvavtsPrgnlvavwdlasgelleeaaladaagvaa 265
                  ++ agY  ++a++ +g+++ ++  +g+ + +wd ++g++ ++ +     g+a+
  EEA22012.1 498 GHNTAGYAIDIAFSPDGQFL-ASGDSGGYACFWDWKTGKMYHKLQAGGKDGLAV 550
                 567789*********98665.899****************99998877777665 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.1      0.12   3.1e+02     224     244 ..     272     291 ..     266     303 .. 0.84
   2 ?    4.4   0.0    0.0057        15     185     215 ..     323     354 ..     303     363 .. 0.84
   3 ?    2.5   0.0     0.023        58     189     215 ..     504     530 ..     478     562 .. 0.81

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.12
    Ge1_WD40 224 prCLheWkPhdGkslssllfl 244
                 ++ +h Wk h  k+++sl f 
  EEA22012.1 272 RKLVHSWKSHT-KPITSLRFF 291
                 5678******6.9****9886 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.0057
    Ge1_WD40 185 eehs.liveaafspdGtalatasedGevkffq 215
                 + hs  i++++f p G +  tas d ++k++ 
  EEA22012.1 323 SGHSkSISDTTFHPTGKTFLTASYDRQIKLWD 354
                 4566689*********************9996 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.023
    Ge1_WD40 189 liveaafspdGtalatasedGevkffq 215
                   ++ afspdG  la   + G+  f+ 
  EEA22012.1 504 YAIDIAFSPDGQFLASGDSGGYACFWD 530
                 678899***************999996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (576 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       362  (0.0201908); expected 358.6 (0.02)
Passed bias filter:                      303  (0.0169); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.65u 0.33s 00:00:00.98 Elapsed: 00:00:00.51
# Mc/sec: 3395.30
//
Query:       EEA22013.1  [L=138]
Description: endosomal cargo receptor (Erv14), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.4e-48  164.2  12.6    1.6e-48  164.1  12.6    1.0  1  Cornichon  Cornichon protein


Domain annotation for each model (and alignments):
>> Cornichon  Cornichon protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  164.1  12.6   8.9e-53   1.6e-48       1     122 []       5     126 ..       5     126 .. 0.99

  Alignments for each domain:
  == domain 1  score: 164.1 bits;  conditional E-value: 8.9e-53
   Cornichon   1 allfilaliltaallflsvyfiialsDleadyinpidlcsklNplvlpelilhafltllfllsgewilfllnlpllayniyrvmskqglydpteifnql 99 
                 a+l++la++++a++lfl+v+f+i++sDle+dy+npi+lc++lN +++pe+++haflt+lf+++g+w++++lnlpllayn ++++ +q+l+d+teif++l
  EEA22013.1   5 AWLYLLAVLINAVNLFLQVFFTIMYSDLECDYLNPIELCNRLNTYIVPEAAVHAFLTFLFVINGYWLAIILNLPLLAYNGKKIFDNQHLLDATEIFRKL 103
                 69************************************************************************************************* PP

   Cornichon 100 kkhkkesmiklafylllffiyLY 122
                 + hk+es+ikl+f+ll+ff+yLY
  EEA22013.1 104 NIHKRESFIKLGFHLLMFFFYLY 126
                 **********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (138 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       525  (0.0292822); expected 358.6 (0.02)
Passed bias filter:                      210  (0.0117129); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.26s 00:00:00.67 Elapsed: 00:00:00.42
# Mc/sec: 975.33
//
Query:       EEA22014.1  [L=138]
Description: endosomal cargo receptor (Erv14), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.4e-48  164.2  12.6    1.6e-48  164.1  12.6    1.0  1  Cornichon  Cornichon protein


Domain annotation for each model (and alignments):
>> Cornichon  Cornichon protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  164.1  12.6   8.9e-53   1.6e-48       1     122 []       5     126 ..       5     126 .. 0.99

  Alignments for each domain:
  == domain 1  score: 164.1 bits;  conditional E-value: 8.9e-53
   Cornichon   1 allfilaliltaallflsvyfiialsDleadyinpidlcsklNplvlpelilhafltllfllsgewilfllnlpllayniyrvmskqglydpteifnql 99 
                 a+l++la++++a++lfl+v+f+i++sDle+dy+npi+lc++lN +++pe+++haflt+lf+++g+w++++lnlpllayn ++++ +q+l+d+teif++l
  EEA22014.1   5 AWLYLLAVLINAVNLFLQVFFTIMYSDLECDYLNPIELCNRLNTYIVPEAAVHAFLTFLFVINGYWLAIILNLPLLAYNGKKIFDNQHLLDATEIFRKL 103
                 69************************************************************************************************* PP

   Cornichon 100 kkhkkesmiklafylllffiyLY 122
                 + hk+es+ikl+f+ll+ff+yLY
  EEA22014.1 104 NIHKRESFIKLGFHLLMFFFYLY 126
                 **********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (138 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       525  (0.0292822); expected 358.6 (0.02)
Passed bias filter:                      210  (0.0117129); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.44
# Mc/sec: 935.27
//
Query:       EEA22015.1  [L=138]
Description: endosomal cargo receptor (Erv14), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.4e-48  164.2  12.6    1.6e-48  164.1  12.6    1.0  1  Cornichon  Cornichon protein


Domain annotation for each model (and alignments):
>> Cornichon  Cornichon protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  164.1  12.6   8.9e-53   1.6e-48       1     122 []       5     126 ..       5     126 .. 0.99

  Alignments for each domain:
  == domain 1  score: 164.1 bits;  conditional E-value: 8.9e-53
   Cornichon   1 allfilaliltaallflsvyfiialsDleadyinpidlcsklNplvlpelilhafltllfllsgewilfllnlpllayniyrvmskqglydpteifnql 99 
                 a+l++la++++a++lfl+v+f+i++sDle+dy+npi+lc++lN +++pe+++haflt+lf+++g+w++++lnlpllayn ++++ +q+l+d+teif++l
  EEA22015.1   5 AWLYLLAVLINAVNLFLQVFFTIMYSDLECDYLNPIELCNRLNTYIVPEAAVHAFLTFLFVINGYWLAIILNLPLLAYNGKKIFDNQHLLDATEIFRKL 103
                 69************************************************************************************************* PP

   Cornichon 100 kkhkkesmiklafylllffiyLY 122
                 + hk+es+ikl+f+ll+ff+yLY
  EEA22015.1 104 NIHKRESFIKLGFHLLMFFFYLY 126
                 **********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (138 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       525  (0.0292822); expected 358.6 (0.02)
Passed bias filter:                      210  (0.0117129); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.27s 00:00:00.67 Elapsed: 00:00:00.44
# Mc/sec: 934.67
//
Query:       EEA22016.1  [L=138]
Description: endosomal cargo receptor (Erv14), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.4e-48  164.2  12.6    1.6e-48  164.1  12.6    1.0  1  Cornichon  Cornichon protein


Domain annotation for each model (and alignments):
>> Cornichon  Cornichon protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  164.1  12.6   8.9e-53   1.6e-48       1     122 []       5     126 ..       5     126 .. 0.99

  Alignments for each domain:
  == domain 1  score: 164.1 bits;  conditional E-value: 8.9e-53
   Cornichon   1 allfilaliltaallflsvyfiialsDleadyinpidlcsklNplvlpelilhafltllfllsgewilfllnlpllayniyrvmskqglydpteifnql 99 
                 a+l++la++++a++lfl+v+f+i++sDle+dy+npi+lc++lN +++pe+++haflt+lf+++g+w++++lnlpllayn ++++ +q+l+d+teif++l
  EEA22016.1   5 AWLYLLAVLINAVNLFLQVFFTIMYSDLECDYLNPIELCNRLNTYIVPEAAVHAFLTFLFVINGYWLAIILNLPLLAYNGKKIFDNQHLLDATEIFRKL 103
                 69************************************************************************************************* PP

   Cornichon 100 kkhkkesmiklafylllffiyLY 122
                 + hk+es+ikl+f+ll+ff+yLY
  EEA22016.1 104 NIHKRESFIKLGFHLLMFFFYLY 126
                 **********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (138 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       525  (0.0292822); expected 358.6 (0.02)
Passed bias filter:                      210  (0.0117129); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.43
# Mc/sec: 974.62
//
Query:       EEA22017.1  [L=138]
Description: endosomal cargo receptor (Erv14), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.4e-48  164.2  12.6    1.6e-48  164.1  12.6    1.0  1  Cornichon  Cornichon protein


Domain annotation for each model (and alignments):
>> Cornichon  Cornichon protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  164.1  12.6   8.9e-53   1.6e-48       1     122 []       5     126 ..       5     126 .. 0.99

  Alignments for each domain:
  == domain 1  score: 164.1 bits;  conditional E-value: 8.9e-53
   Cornichon   1 allfilaliltaallflsvyfiialsDleadyinpidlcsklNplvlpelilhafltllfllsgewilfllnlpllayniyrvmskqglydpteifnql 99 
                 a+l++la++++a++lfl+v+f+i++sDle+dy+npi+lc++lN +++pe+++haflt+lf+++g+w++++lnlpllayn ++++ +q+l+d+teif++l
  EEA22017.1   5 AWLYLLAVLINAVNLFLQVFFTIMYSDLECDYLNPIELCNRLNTYIVPEAAVHAFLTFLFVINGYWLAIILNLPLLAYNGKKIFDNQHLLDATEIFRKL 103
                 69************************************************************************************************* PP

   Cornichon 100 kkhkkesmiklafylllffiyLY 122
                 + hk+es+ikl+f+ll+ff+yLY
  EEA22017.1 104 NIHKRESFIKLGFHLLMFFFYLY 126
                 **********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (138 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       525  (0.0292822); expected 358.6 (0.02)
Passed bias filter:                      210  (0.0117129); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.21s 00:00:00.63 Elapsed: 00:00:00.41
# Mc/sec: 1018.47
//
Query:       EEA22018.1  [L=1062]
Description: ABC transporter (Adp1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.9e-39  134.2  19.9    7.3e-39  133.4  19.9    1.5  1  ABC2_membrane    ABC-2 type transporter
    3.1e-26   92.5   1.5    3.4e-26   92.4   0.1    1.8  2  ABC_tran         ABC transporter
      2e-05   23.9  22.4      2e-05   23.9  22.4    2.1  2  ABC2_membrane_3  ABC-2 family transporter protein
    2.2e-05   24.4   0.4       0.12   12.2   0.0    2.4  2  AAA_21           AAA domain, putative AbiEii toxin, Type IV T
     0.0022   17.7   0.0     0.0046   16.7   0.0    1.5  1  AAA_29           P-loop containing region of AAA domain
      0.003   17.5   0.0      0.006   16.5   0.0    1.4  1  RsgA_GTPase      RsgA GTPase
     0.0098   16.3   0.0      0.023   15.1   0.0    1.6  1  AAA_16           AAA ATPase domain
  ------ inclusion threshold ------
      0.015   15.8   0.1      0.054   14.1   0.0    1.9  2  AAA_18           AAA domain
       0.04   13.5   0.0       0.12   12.0   0.0    1.7  1  AAA_25           AAA domain
      0.063   12.7   0.0        0.5    9.8   0.0    2.3  1  SMC_N            RecF/RecN/SMC N terminal domain
       0.11   13.5   1.6       0.23   12.5   1.6    1.5  1  KCNQ2_u3         Unstructured region on Potassium channel sub


Domain annotation for each model (and alignments):
>> ABC2_membrane  ABC-2 type transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  133.4  19.9   4.5e-42   7.3e-39       1     209 [.     789     999 ..     789    1000 .. 0.97

  Alignments for each domain:
  == domain 1  score: 133.4 bits;  conditional E-value: 4.5e-42
  ABC2_membrane   1 tqikallkreflqrwrdpslgllwrliqplllalvfgtvfgnlg.nsedglnrpgllffsvlflafsaltsvapvferergvlerelvsplyslsa 95 
                    +q+ +l +r++++ +r+p+l  l+  +  +lla+++g++f++l  + ++++nr+gl+ff++  ++fs+lts+ +vf +er +++re+++++ys+ a
     EEA22018.1 789 RQFIILSNRTWRNLYRNPMLM-LTHYAISILLAVLCGYLFYGLTdDIKGFQNRLGLFFFILALFGFSTLTSL-TVFSSERLLFVRERANGYYSPLA 882
                    59****************999.********************9856777779********************.*********************** PP

  ABC2_membrane  96 yvlakvlve.lpvsllqalifllivyflvgldls..rfflflllllltalaasslgllisalapsfedasqlaslvllpllllsGffipidsmpkw 188
                    y+ akv+++ +p+ l+  li+ +ivy+++gl +    f+ fll+l+l+ laa ++ l+i++++++  +a++++slv+l+ ll++G + + d++p  
     EEA22018.1 883 YFCAKVIFDiVPLRLIPPLIMGVIVYPMTGLIPAwpEFLRFLLILVLFNLAAAGICLFIGIVFRDGGVANLIGSLVMLFSLLFAGLLLNHDAIPPA 978
                    *********99**********************99999*******************************************************77* PP

  ABC2_membrane 189 lqwiaylnPltyavealrsnl 209
                      w++ l+ + y++eal++n+
     EEA22018.1 979 ALWLQTLSIFHYGFEALIVNE 999
                    *****************9997 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.4   0.1   2.1e-29   3.4e-26       8     137 .]     392     539 ..     385     539 .. 0.96
   2 ?   -2.5   0.3       4.2   6.9e+03      60      80 ..     655     688 ..     639     725 .. 0.55

  Alignments for each domain:
  == domain 1  score: 92.4 bits;  conditional E-value: 2.1e-29
                 EETTSEEEEEESTTSSHHHHHHHHTTSS--..SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH................HHHTCHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................xxxxxxxxx RF
    ABC_tran   8 lkegekvaivGenGaGKStLlkllagllkp..teGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren................esdeeieka 88 
                  ++ge++a++G +GaGKSt+l +la++ k   t+G+  ++g+++++     +++ ig++ qe+++ p+ltv+e+                +++++++++
  EEA22018.1 392 AQPGEITAVMGASGAGKSTFLDILARKNKRgvTQGDFYINGEKISD---ADFKSMIGFVDQEDTMLPTLTVHETiltsallrlpkdmsrfAKEQRVTEV 487
                 689************************99999**************...99************************************************ PP

                 HHHSTTGGTTCBGESTTS...GGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                 xxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  89 lsklglkelkdtvvkssp...ssLSgGqkqrvalarallkkpkllllDEpta 137
                  ++lg++++kd++++s+    + +SgG+k+rv +a+ l++ p++l+lDEpt+
  EEA22018.1 488 EKQLGIHHIKDQIIGSEEghgRGISGGEKRRVGIACELVTSPSILFLDEPTS 539
                 **************99999999****************************96 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 4.2
                 CEEEE-SS--S-TTSBHHHH.............H CS
                 xxxxxxxxxxxxxxxxxxxx.............x RF
    ABC_tran  60 eigvlpqepqlfpeltvren.............e 80 
                  ++ +   +++  e tvr+n              
  EEA22018.1 655 AVKSIASASNVSIEETVRNNqenssrpstkrqqS 688
                 4445555555666666666654333332222210 PP

>> ABC2_membrane_3  ABC-2 family transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   6.2       0.1   1.6e+02     212     261 ..     811     864 ..     804     865 .. 0.68
   2 !   23.9  22.4   1.2e-08     2e-05     165     344 ..     842    1051 ..     831    1052 .. 0.78

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.1
  ABC2_membrane_3 212 gdflvyllqlllilllafgl..gipfg..nlglllllfllfglayialgyllss 261
                      + +++++l ++l+ +l++gl   i  +   lgl+++ + lfg+++++  +++ss
       EEA22018.1 811 THYAISILLAVLCGYLFYGLtdDIKGFqnRLGLFFFILALFGFSTLTSLTVFSS 864
                      445566666666666777745533333557789999999999999888888775 PP

  == domain 2  score: 23.9 bits;  conditional E-value: 1.2e-08
  ABC2_membrane_3  165 gliliilifitasfiav..siveEkesrikelqlvsgvsplqywlskilgdfl.vyllqlllilllafglgipfg.....nlglllllfllf 248 
                       gl+++il+++++s +++   + +E+   ++e+      spl+y+ +k+++d + + l++ l++ ++++   ++       +++ +ll ++lf
       EEA22018.1  842 GLFFFILALFGFSTLTSltVFSSERLLFVRERANGY-YSPLAYFCAKVIFDIVpLRLIPPLIMGVIVYP--MTGLipawpEFLRFLLILVLF 930 
                       45555555555553333113489*************.**************875889999***999666..33333445899********** PP

  ABC2_membrane_3  249 glayialgyllsslfknsetaqilifivilllsgffgglfp.ledlpsalkwifsiiPffapglgllrlitgd.plwe.............. 324 
                        la++ + ++++ +f++ + a+++ ++v+l +s++f+gl +  +++p  ++ ++  + +f++g  +  li ++ ++ +              
       EEA22018.1  931 NLAAAGICLFIGIVFRDGGVANLIGSLVML-FSLLFAGLLLnHDAIPP-AALWLQTLSIFHYG--FEALIVNEvTFLTlidhkygldievpg 1018
                       ******************************.99999999766887777.45555555555543..333343332444467788888889999 PP

  ABC2_membrane_3  325 .............illsliilalfavvylllal 344 
                                    ++ ++i l ++++v+++la+
       EEA22018.1 1019 asilsafgfdtlaLWGDVIGLGIISAVFIVLAY 1051
                       999999999999999*************99996 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.4   0.1   0.00026      0.42       1      20 [.     397     416 ..     397     453 .. 0.78
   2 !   12.2   0.0   7.2e-05      0.12     249     299 ..     523     571 ..     417     572 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00026
      AAA_21   1 lnvliGpNgsGKSnLLdald 20 
                 ++++ G+ g+GKS++Ld+l 
  EEA22018.1 397 ITAVMGASGAGKSTFLDILA 416
                 79999**************5 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 7.2e-05
      AAA_21 249 tallralkkgsllliDEpEngLHPkllrrllell.kelsrngaQviltTHSp 299
                   l   +   s+l++DEp +gL+      ++e l  ++++ +  vi+t H+p
  EEA22018.1 523 CELVTSP---SILFLDEPTSGLDAFNAFNVIECLvTLAKTYNRTVIFTIHQP 571
                 4444444...**************9999999999655555889****98887 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   2.8e-06    0.0046      22      40 ..     395     413 ..     383     417 .. 0.85

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 2.8e-06
      AAA_29  22 kgatlltGpsGsGKSTllD 40 
                  ++t ++G+sG+GKST+lD
  EEA22018.1 395 GEITAVMGASGAGKSTFLD 413
                 449***************9 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   3.7e-06     0.006      79     125 ..     374     421 ..     351     428 .. 0.76

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 3.7e-06
                  EEE--TTTHTTHHHHHHHCTT.SEEEEECSTTSSHHHHHHHHCTT--- CS
  RsgA_GTPase  79 vllvsaktkegleelkellkd.ktsvlvGqSGvGKStLinallpelel 125
                   +  + + k+ l +++ + +  ++++++G SG+GKSt+++ l+ +++ 
   EEA22018.1 374 RVSYNLNGKQILLDIQGVAQPgEITAVMGASGAGKSTFLDILARKNKR 421
                  55566666677778888888779******************9987655 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   1.4e-05     0.023      20     106 ..     392     468 ..     382     561 .. 0.69

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 1.4e-05
      AAA_16  20 rsgrpelvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipysalaqalareellrqlldeaesaeleawrekleeala 106
                 ++++ e++ + G+sG GKs+ ++ l+r  +     +++g++  ++++i+ + + +++   +++ q++++         +e++++++ 
  EEA22018.1 392 AQPG-EITAVMGASGAGKSTFLDILARKNK---RGVTQGDFYINGEKISDADFKSMI---GFVDQEDTM---LPTLTVHETILTSAL 468
                 4443.89***************99997444...559999999996664433344444...333333333...333333333433333 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   3.3e-05     0.054       3      44 ..     400     451 ..     399     488 .. 0.82
   2 ?   -3.1   0.0       6.7   1.1e+04      46      66 ..     675     695 ..     637     716 .. 0.56

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 3.3e-05
      AAA_18   3 ltGtpGvGKttlakeLskrlgf..........gvnlrdvakenglllevdpe 44 
                 ++G++G+GK+t+ + L+++++           g++++d  +++++ + ++++
  EEA22018.1 400 VMGASGAGKSTFLDILARKNKRgvtqgdfyinGEKISDADFKSMIGFVDQED 451
                 89****************9766678888888888888888887777766665 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 6.7
      AAA_18  46 ldeskrldedkldklldalee 66 
                  ++s r  ++++++l +  ++
  EEA22018.1 675 QENSSRPSTKRQQSLKQRQDK 695
                 334444444444444443333 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   7.1e-05      0.12      26      55 ..     388     417 ..     384     427 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 7.1e-05
      AAA_25  26 vkgllpagelallaGapgtGKttlaldlal 55 
                 ++g+   ge+++++Ga+g+GK+t++  la 
  EEA22018.1 388 IQGVAQPGEITAVMGASGAGKSTFLDILAR 417
                 789999******************977775 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0   0.00031       0.5      25     197 ..     396     568 ..     381     589 .. 0.68

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00031
                 SEEEEEESTTSSHHHHHHHHHHHCTT.TTTTTTCHCCCCCC--BTTCSSTTEEEEEEEEEETTEESSSSSSCEEEEEEEETTSEEEEEETTEEE-HHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  25 sftaivGpNGSGKsnlldAilFvLGersakklrseklsdlihkskekasvkkaeveitfdnedkklkiekeevsisrrvkrkgeseykingkevtkkev 123
                 ++ta++G+ G+GKs +ld +      ++++    ++ +  i+  ++ + +++ ++  ++d+ed  l++ + + +i +++      ++    ke + +ev
  EEA22018.1 396 EITAVMGASGAGKSTFLDIL----ARKNKR--GVTQGDFYING-EKISDADFKSMIGFVDQEDTMLPTLTVHETILTSALLRLPKDMSRFAKEQRVTEV 487
                 58999999999999999966....544442..33334444555.6666666666666678888886554443333333333333333333455566677 PP

                 HHHHHCTT-STT..........CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTT.SEEEEE-S CS
                 xxxxxxxxxxxx..........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxx RF
       SMC_N 124 sellesagiske..........lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkekskn.aQfivisl 197
                 +++l  ++i+ +           +SgGek  v +a     + v   ++ +lDe  + LD+ n  +v e l +  k+    ++ ++
  EEA22018.1 488 EKQLGIHHIKDQiigseeghgrGISGGEKRRVGIAC----ELVTSPSILFLDEPTSGLDAFNAFNVIECLVTLAKTyNRTVIFTI 568
                 778877777777888889999999*****9888765....45666778889********99999999999877766333444444 PP

>> KCNQ2_u3  Unstructured region on Potassium channel subunit alpha KvLQT2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   1.6   0.00014      0.23      12      89 ..     642     732 ..     639     739 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00014
    KCNQ2_u3  12 sreekekeekitkivrssssmgqknfsap.saasesqcrPstswqqqlqeeqqr.......saw......ngssPvgdsgslvRiPPPPahe 89 
                 +r++ +  ++  + v+s +s+++ +++++    +e+++rPst  qq l+++q++       s+w      n+ +P    ++l  +PPP +  
  EEA22018.1 642 QRDNLKTASSSLRAVKSIASASNVSIEETvRNNQENSSRPSTKRQQSLKQRQDKqlftrqnSHWlrlssrNSGAPQVT-EDLDNLPPPASGT 732
                 5666667777788999999999999999867888999******99988887777566666533366665566666543.3699999998865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1062 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1459  (0.0813765); expected 358.6 (0.02)
Passed bias filter:                      828  (0.0461822); expected 358.6 (0.02)
Passed Vit filter:                       104  (0.00580066); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.95u 0.33s 00:00:01.28 Elapsed: 00:00:00.45
# Mc/sec: 7040.91
//
Query:       EEA22019.1  [L=418]
Description: aminotransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      2e-40  139.1   0.0    2.4e-40  138.8   0.0    1.1  1  Aminotran_1_2    Aminotransferase class I and II
    4.6e-08   32.4   0.0    1.5e-07   30.8   0.0    1.7  2  Aminotran_5      Aminotransferase class-V
    4.6e-06   25.4   0.0    6.8e-06   24.9   0.0    1.2  1  Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
    3.2e-05   23.4   0.0    6.2e-05   22.4   0.0    1.4  1  Beta_elim_lyase  Beta-eliminating lyase
     0.0097   14.8   0.0      0.017   14.0   0.0    1.4  1  Alliinase_C      Allinase
  ------ inclusion threshold ------
       0.02   15.0   0.1      0.086   12.9   0.0    2.0  2  zf-C3HC          C3HC zinc finger-like


Domain annotation for each model (and alignments):
>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.8   0.0   8.1e-44   2.4e-40      35     362 ..      62     401 ..      44     402 .. 0.85

  Alignments for each domain:
  == domain 1  score: 138.8 bits;  conditional E-value: 8.1e-44
                    TSTTST-BTTHHHHHHHHHHHHHCTCTTCHTTGGEGEEEESHHHHHHHHHHHHHHHTTT-EEEEEESS-THHHHHHHHTTSEEEEEEBEET....T CS
  Aminotran_1_2  35 gtlneygpidglpeleealakflgrseklklkreaavvvgsGagaliealifllklnpgdeilvpdptyasyknilrlsggevvryplyse....e 126
                     t   yg i+g+ +l++ l ++++ +  + l +e +++ +sGa +++ +l  +l ++pgd ++v+ pty +   + ++ g+ev  ++ ++     +
     EEA22019.1  62 TTKLTYGAIRGSETLRSHLSRLYSVKTPTVLPTE-NILITSGAIQGNFLLHYAL-VQPGDHVIVHYPTYQQLYSVSEAIGAEVSLWKAKEDesdeN 155
                    56678*******************6666777788.9******************.9*******************************88768999* PP

                    TTEE-HHHHHHHHTTHHCTTETEEEEEEESS-TTT--B--HHHHHHHHHHHHHTTEEEEEEETTTTCBSSSS..HTHHH....HGGSTTSTTEEEE CS
  Aminotran_1_2 127 dfhldlealeealkeapegnkktkvilvesphNPtGtvatleeleklldlakkynlllfvDeaYagfvfgsl..davat....ranveeepnlliv 216
                    ++ ld e+l+ +++        tk+i++++p+NPtG+++++ +l++++++ak++ +++  De+Y     g +  d   +     ++   + n++++
     EEA22019.1 156 GWVLDTEELKGLIRP------NTKLIVLNNPQNPTGAIIPKSKLQEIVNIAKEQSIIIHADEVYRPIFHGISpiD---AefppSLLSLGYENVVVT 242
                    **************9......99***********************************************55342...25664444445566**** PP

                    EESSSTTSSGGG-EEEEEE.EHHHHHHHHHHHH.HHTSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS..TEEEECCSCSSEE CS
  Aminotran_1_2 217 gslsKafGlaGeRvGyilg.naavvsqlrklsr.pflsssllqaavaaalsdallkqseleemrqrlqkrrkelrdeLael..glkvlasqsgmfl 308
                    +s+sKa++laG+RvG+i++ n+++++        + +s s+   ava  + +++ + s l  + q  +k+   l + +++     ++ ++ +g   
     EEA22019.1 243 SSMSKAYSLAGIRVGWIAArNKEIIDKCMVCRDyTTISVSQIDDAVASYALAPHTIHSLLLRNIQLAKKNPAILEKFIESHrwACDWKKPRAGTTA 338
                    *******************98888776555555055558999999999999999887777777777777777777777666555556777799999 PP

                    EEEETHH....CHHHHHHHHHHTCTEEEEEGGGGTS......TTEEEEECTTS-HHHHHHHHHH CS
  Aminotran_1_2 309 ltdlsae....takelskkLleevgvyvtpgtsftv......pgrlRitvAglteeeleelvea 362
                    ++++++     ++ +++k Lle++gv+v+pg+ +        +g +R+ +  + +e le+ +e+
     EEA22019.1 339 FVRFNKMgrpvDDVAFCKLLLEKKGVLVVPGSRCFGrdagefRGYVRLGY-VCETEVLERGLEK 401
                    99999999999*******************98665568888888999998.8888888888876 PP

>> Aminotran_5  Aminotransferase class-V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.8   0.0   4.9e-11   1.5e-07      61     177 ..      94     212 ..      47     216 .. 0.79
   2 ?   -1.7   0.0      0.35     1e+03     322     342 ..     353     373 ..     298     392 .. 0.62

  Alignments for each domain:
  == domain 1  score: 30.8 bits;  conditional E-value: 4.9e-11
                  GGGEEEESSHHHHHHHHHHHCCCC-TTTSEEEEETTSHGGGTHHHHHHHHHHTEEEEEEEBETT......SCBEGGGHHHH--TTEEEEEEESBETTT CS
  Aminotran_5  61 eeeiiftsGtteainlvalslarslkpgdeivvteaehhanlvpwqelakrtgakvkvipldee......geldldelekllnektklvaithvsnvt 152
                  +e+i+ tsG+ +++ l  ++l   ++pgd+++v    ++        ++++ ga+v  ++++e+      + ld++el+ l++++tkl+ ++  +n t
   EEA22019.1  94 TENILITSGAIQGNFLLHYAL---VQPGDHVIVHYPTYQQL----YSVSEAIGAEVSLWKAKEDesdengWVLDTEELKGLIRPNTKLIVLNNPQNPT 184
                  589******************...*********88777654....58888889999999887642222236799************************ PP

                  TEB--...HHHHHHHHHHTT-EEEEE-T CS
  Aminotran_5 153 Gtiqp...veeigklakkkgalvlvDaa 177
                  G i p   ++ei+++ak++ +++++D +
   EEA22019.1 185 GAIIPkskLQEIVNIAKEQSIIIHADEV 212
                  **987555899***************76 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.35
                  HHHHHHHHHTTEEEEEE-TTT CS
  Aminotran_5 322 edvatlLdeegIavrsGhhca 342
                  +  + lL+++g+ v  G++c 
   EEA22019.1 353 AFCKLLLEKKGVLVVPGSRCF 373
                  334567888899999999997 PP

>> Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.9   0.0   2.3e-09   6.8e-06      76     176 ..     103     213 ..      73     224 .. 0.80

  Alignments for each domain:
  == domain 1  score: 24.9 bits;  conditional E-value: 2.3e-09
                      HHHHHHHHHHTTS-TTEEEEEESTSSHHHHHHHHHTHHHTTCEEEEEST.......TSHHHHHHHCCTTEEEEEEESS-TTTT---...-HHHH CS
  Cys_Met_Meta_PP  76 GmaAiaaailallkaGdeivvsddlYggtqrllkkvlkklgievkfvdt.......sdleelekaikentklvylEtptnpllkvv...Dieki 159
                           ++   al++ Gd+++v+   Y+  +++ + +  ++++     d         d+eel+  i++ntkl+ l  p np+  ++    +++i
       EEA22019.1 103 AIQGNFLLHYALVQPGDHVIVHYPTYQQLYSVSEAIGAEVSLWKAKEDEsdengwvLDTEELKGLIRPNTKLIVLNNPQNPTGAIIpksKLQEI 196
                      34455566789************99999999999888876665555554333555568899*********************9996444799** PP

                      HHHHHHTT-EEEEEGTT CS
  Cys_Met_Meta_PP 160 aklakkagvlvvvDntf 176
                      +++ak++++++  D ++
       EEA22019.1 197 VNIAKEQSIIIHADEVY 213
                      **********9999865 PP

>> Beta_elim_lyase  Beta-eliminating lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.4   0.0   2.1e-08   6.2e-05      48     167 ..      95     210 ..      60     212 .. 0.75

  Alignments for each domain:
  == domain 1  score: 22.4 bits;  conditional E-value: 2.1e-08
                      SEEEEES-HHHHHHHHHHHH--TTEEEEEETT-HHHHSSTTHH..HHCC--EEEEE-EBTT.TBE-HHHHHHHS--S-TTS-EEEEEEEESSBT CS
  Beta_elim_lyase  48 eaalfvpqGtaAnsillkillqrgeevivtepahihfdetgai..aelagvklrdlknkea.GkmdlekleaaikevgaheekiklisltvTnn 138
                      e +l +    ++n +l  +l+q+g+ viv+ p     +    +  ae++  k+++ +++e+   +d e+l+ +i++      ++kli+l +  n
       EEA22019.1  95 ENILITSGAIQGNFLLHYALVQPGDHVIVHYPTYQQLYSVSEAigAEVSLWKAKEDESDENgWVLDTEELKGLIRP------NTKLIVLNNPQN 182
                      444444444578999999999***********766666553320022233333444444443579**********9......799********* PP

                      TTTTB---HHHHHHHHHHHHHCT-EEEEE CS
  Beta_elim_lyase 139 tagGqvvsleelrevaaiakkygiplhlD 167
                         G +++  +l+e+ +iak++ i +h D
       EEA22019.1 183 P-TGAIIPKSKLQEIVNIAKEQSIIIHAD 210
                      5.9************************99 PP

>> Alliinase_C  Allinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.0   0.0   5.8e-06     0.017     145     230 ..     179     283 ..     117     295 .. 0.72

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 5.8e-06
                  SS-TTT---......-----..-TT-EEEEEE-TT-STTT...S---S-B........--SE.EEEEHHHHHS-GGG-EEEEEES-HHHHHHHHHHHH CS
  Alliinase_C 145 sPnnPdgll......reavv..kgseakviyDlayYWPhy...tpitska........dedi.mLftlskltGhaGsrlGWalvkdkevakklveyie 222
                   P nP g++      +e  v  +++++++i+    Y P +   +pi ++          e++ +  ++sk    aG+r+GW   ++ke+ +k +    
   EEA22019.1 179 NPQNPTGAIipksklQEI-VniAKEQSIIIHADEVYRPIFhgiSPIDAEFppsllslgYENVvVTSSMSKAYSLAGIRVGWIAARNKEIIDKCMVCRD 275
                  566666654222110444.334777888888888888877222344433211111222345404568*************************999999 PP

                  HHHSS--H CS
  Alliinase_C 223 knsiGvsk 230
                   ++i vs+
   EEA22019.1 276 YTTISVSQ 283
                  99999886 PP

>> zf-C3HC  C3HC zinc finger-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.1      0.92   2.7e+03      47      71 ..      26      48 ..      14      56 .. 0.70
   2 ?   12.9   0.0   2.9e-05     0.086      27      99 ..     249     339 ..     234     354 .. 0.78

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.92
     zf-C3HC 47 evCgaslvlklksseeesdeqlnkk 71
                e+C as++l+  + ++ s+eq  ++
  EEA22019.1 26 ETCSASISLS--DLQNLSSEQSTDS 48
                6899999999..4444444444333 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 2.9e-05
     zf-C3HC  27 selkcAkrGWkcvs.kdrl.kCevCgaslvlkl...............ksseeesdeqlnkklaekylkqlveaHeenClWrnkecp.esl 99 
                  +l+  + GW+    k+++ kC vC+ +  +++               +     +++ +  k +  +l++++e+H+ +C W++     + +
  EEA22019.1 249 YSLAGIRVGWIAARnKEIIdKCMVCRDYTTISVsqiddavasyalaphTIHSLLLRNIQLAKKNPAILEKFIESHRWACDWKKPRAGtTAF 339
                 55555689**99662555578*******9999999**********986555666778888889999****************977764555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (418 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       655  (0.036533); expected 358.6 (0.02)
Passed bias filter:                      577  (0.0321825); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.41
# Mc/sec: 3061.37
//
Query:       EEA22020.1  [L=641]
Description: long-chain fatty acid transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.1e-66  225.2   0.0    1.5e-66  224.8   0.0    1.1  1  AMP-binding    AMP-binding enzyme
    4.7e-11   43.5   0.0    2.4e-10   41.3   0.0    2.1  2  AMP-binding_C  AMP-binding enzyme C-terminal domain


Domain annotation for each model (and alignments):
>> AMP-binding  AMP-binding enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  224.8   0.0   1.7e-70   1.5e-66       5     422 ..      70     504 ..      65     505 .. 0.82

  Alignments for each domain:
  == domain 1  score: 224.8 bits;  conditional E-value: 1.7e-70
                  HHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHH.HTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEEE.. CS
  AMP-binding   5 aaktpdkvalvdsgegqtlTYreldervnrlAagLr.slGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakvli.. 99 
                  a+k  +++++v+   gqt+TY+e ++ v r++++++   Gvk+++ V++   ns+ +++++l++ ++Ga+++ +n +l+ + l+++++ s a++++  
   EEA22020.1  70 AQKSANQPFIVY--NGQTWTYKEAYDTVLRYGQYFKnTYGVKPKEIVGLDFMNSATYIFIWLGLSSIGAIPAFINYNLSGKPLSHCIKVSTARLVVad 165
                  577779******..9*********************999*********************************************************86 PP

                  ...E.TCTCCCHHHHHHHHSCC-EECEEEEESCCS-HC...CHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHH CS
  AMP-binding 100 ...a.tvdselleklleaaakleavklvivldadellk...eeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvas 190
                     + +  +e+    l++ a+++ ++ +  +d   +      + l++ +  e+    +   +++   dla++iYTSGTTG PK +++s     + +  
   EEA22020.1 166 eeiReKFTEEQ----LAEFASPDFRDGKGPVDVVFITPeieDQILQSLAIRED----DSVRSNAAMRDLAVLIYTSGTTGYPKPAVVSLSKCWSGAIF 255
                  54413222222....22222233333333333333333000333443333332....234557999*************************9999888 PP

                  HHHHHCSCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT.-SE CS
  AMP-binding 191 lkletrfklkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlss.lrl 287
                  ++     +lk dd+v++++pl+h++g +l+ +++l++Gat+vl +k++a++   +++++++  +t+i++v + +++ll+ ++        dl + +r+
   EEA22020.1 256 ID--GFLSLKTDDRVYTCMPLYHATGAVLGFCAVLFKGATIVLGHKFSARN---FWNDVRDGDATIIQYVGETMRYLLAMPKN-------DLEKkHRI 341
                  64..3366888************************************9966...57***********************8533.......67776999 PP

                  EEEESS-EBHHHHHHHHHHHTC.EEEEEEEEGGGSSECEE....CHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBEE.............TTSEEEE CS
  AMP-binding 288 vllggeplspellrffralfge.evlegYGlTEttgvvtv....lpleedkkklgsvGkplpgvevkivDeetgepvp.............dgeeGel 367
                   l+ g+ ++p+++ +++++fg  ++ e Y  TE      +    +  ++   + g  G  l g  +++v+ ++++++p             +ge+Gel
   EEA22020.1 342 RLAYGNGMRPDVWPQVKQRFGIeTIAEFYSSTEGFSGHWNrsanDFSMGAIGRNGYLGELLLGRTMALVEVDHEQEIPrrdpvtgfctrvpRGEPGEL 439
                  999*******************99*************9744444333444445555668899999****9999999999999********9******9 PP

                  EEE.ET....TS-SEBTT-HHHHHHHEEE....TCC.EEEEEEEEEEETTSEEEEEEECCCEEEE CS
  AMP-binding 368 lvr.gp....gvmkgYlkkpeataeafds....egr.wlrTGDlgrldedGyleivgRkkdlikl 422
                  l    p       +gY+++ ea ++++      +g+ w+rTGD  ++d++G+ ++++R+ d++ +
   EEA22020.1 440 LYAlDPndiaFKYQGYFNNSEASEKKILRdvfaKGDaWFRTGDTLKWDTEGRWYFTDRIGDTFRW 504
                  98844544444889************99678865666*************************987 PP

>> AMP-binding_C  AMP-binding enzyme C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0       0.4   3.6e+03      44      61 ..     166     184 ..     147     204 .. 0.60
   2 !   41.3   0.0   2.7e-14   2.4e-10       1      76 []     513     593 ..     513     593 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.4
                    HHHHHHH.HHHT-TTTS-S CS
  AMP-binding_C  44 eeLkahv.rkelgpyavpk 61 
                    ee++++  +++l+++a p+
     EEA22020.1 166 EEIREKFtEEQLAEFASPD 184
                    5555555233555555554 PP

  == domain 2  score: 41.3 bits;  conditional E-value: 2.7e-14
                    HHHHHHHSSTTEEEEEEE-----.TTS---EEEEEE---...---..HHHHHHHHHHHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   1 evEsalvshpaVaeaaVvGvpde.vkGealvafVvlkdg...sea..leeeLkahvrkelgpyavpkkvvfvdelpktrsGK 76 
                    ev ++l  hp++aea V+Gv+ +  +G+a +a +vlk+g   + +  + e L  hv ++l+ ya p  ++++ el++t + K
     EEA22020.1 513 EVAETLGGHPDIAEANVYGVSLPhHDGRAGCAAIVLKNGtidV-PsdILESLAVHVLANLPRYALPLFLRVTTELERTGNNK 593
                    67899******************99************996542.145********************************988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (641 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       426  (0.0237604); expected 358.6 (0.02)
Passed bias filter:                      399  (0.0222544); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.28s 00:00:00.90 Elapsed: 00:00:00.47
# Mc/sec: 4096.26
//
Query:       EEA22021.1  [L=376]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.056   13.6   0.0        1.8    8.7   0.0    2.4  2  MaoC_dehydrat_N  N-terminal half of MaoC dehydratase


Domain annotation for each model (and alignments):
>> MaoC_dehydrat_N  N-terminal half of MaoC dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.0   9.9e-05       1.8      69     131 ..     129     201 ..      99     202 .. 0.72
   2 ?    2.3   0.0    0.0095   1.7e+02      13      58 ..     255     303 ..     245     345 .. 0.66

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 9.9e-05
  MaoC_dehydrat_N  69 gidlsrllhgeqefeyhe.......piraGDelttesriad....vydkkgvGalefivvettvtnqrGepvat 131
                      + +  r ++++ e+ + +        +r+G +++ ++++ +    +  k+g +++ ++ ve+++ n+rG+ v++
       EEA22021.1 129 SFPFTRRMWAGGEVSWPRqsdgkpnLLRVGQTVRETTKVLSaepkIVRKTG-EEMIVVGVEKRFENERGVAVVD 201
                      667778888888888843344444479999999999999762222555666.999*****************98 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.0095
  MaoC_dehydrat_N  13 evereavrefakavgetnpayldeeaaraa.gyrslia..Pptflivla 58 
                        +  ++ +f   + +++ ++++  +ar+  g+r +++  P  ++ +l+
       EEA22021.1 255 RQTPVSLFRFSALTFNPHKIHYSLPWARDVeGHRNIVVhgPLNLVNMLD 303
                      5566667788888899999999999999988999887744555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (376 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       392  (0.021864); expected 358.6 (0.02)
Passed bias filter:                      315  (0.0175693); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.23s 00:00:00.72 Elapsed: 00:00:00.40
# Mc/sec: 2820.44
//
Query:       EEA22022.1  [L=373]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
  ------ inclusion threshold ------
        1.8    8.5   4.5        6.7    6.7   0.3    2.8  2  Herpes_US9  Alphaherpesvirus tegument protein US9


Domain annotation for each model (and alignments):
>> Herpes_US9  Alphaherpesvirus tegument protein US9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.4    0.0083   1.5e+02      37      51 ..      43      57 ..      30      62 .. 0.82
   2 ?    6.7   0.3   0.00037       6.7       1      17 [.     172     188 ..     172     230 .. 0.72

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.0083
  Herpes_US9 37 tliivllvAvlsaaF 51
                ++ii +++A++++aF
  EEA22022.1 43 LMIIAMILAIIATAF 57
                56888999******9 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.00037
  Herpes_US9   1 aYYsesEdEaAdeFLvR 17 
                 aYYs+s + a d FL  
  EEA22022.1 172 AYYSNSANSACDLFLAV 188
                 8*************975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (373 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       901  (0.0502538); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.24s 00:00:00.68 Elapsed: 00:00:00.38
# Mc/sec: 2918.81
//
Query:       EEA22023.1  [L=572]
Description: isoamyl alcohol oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.8e-21   75.7   3.4    3.9e-21   75.3   1.7    2.2  2  FAD_binding_4  FAD binding domain
    9.9e-10   38.4   3.5    9.9e-10   38.4   3.5    1.9  2  BBE            Berberine and berberine like


Domain annotation for each model (and alignments):
>> FAD_binding_4  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.3   1.7   4.3e-25   3.9e-21       3     138 ..     127     266 ..     125     267 .. 0.92
   2 ?   -2.4   0.0      0.39   3.5e+03      63      81 ..     469     487 ..     466     489 .. 0.85

  Alignments for each domain:
  == domain 1  score: 75.3 bits;  conditional E-value: 4.3e-25
                    EEEEESSHHHHHHHHHHHHHCTSCEEEESSSTTEESTTCSCCEEEEEETTS--EEEEET......TTTEEEEETTSBHHHHHHHHHHHTTECSSGG CS
  FAD_binding_4   3 avvrpeseeevaaalrlaneaglpvlvrGgGssllgqavatggvvldlsrlnrileide......eegtatveaGvtlgdlvealaakglllglep 92 
                    + v ++s+++v+aa+++a+++++++++r++G+++   ++  g++ ++++++n+ +++++      ++   +v+aG+ + ++  a++++gl++    
     EEA22023.1 127 YAVNVSSANDVIAAVNFATRNNIRFVIRNTGHDYFARSTGAGALSVWMHNFNS-IQYKRwadthyTGPAFKVGAGIMGYQIMDAAHKQGLVVV-GG 220
                    6799*******************************77777********99***.67777777777899*****************88887775.99 PP

                    GTTCGSBHHHTTTTT-EETTEEGG--HHGTEEEEEEEETTSEEEEE CS
  FAD_binding_4  93 gsgipgtvGGaiatnagGygsekyGlirdnvlglevvladGevvrl 138
                    ++ + g +GG+i +++++  s+  Gl +dn l+++vv+a+G+++++
     EEA22023.1 221 ECPTVGLAGGYIQGGGHSALSTSFGLGADNALEFQVVTANGKLLTA 266
                    999999*************************************986 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.39
                    TTEEEEETTSBHHHHHHHH CS
  FAD_binding_4  63 egtatveaGvtlgdlveal 81 
                    +  +t + G+++++ + ++
     EEA22023.1 469 NAAVTMQIGTPWKETATWA 487
                    56899********998887 PP

>> BBE  Berberine and berberine like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.2       1.1   9.5e+03       2       7 ..     124     129 ..     124     162 .. 0.67
   2 !   38.4   3.5   1.1e-13   9.9e-10       1      41 [.     513     552 ..     513     557 .. 0.94

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 1.1
                 -TTS-- CS
         BBE   2 YvNyrd 7  
                 YvNy+ 
  EEA22023.1 124 YVNYAV 129
                 888864 PP

  == domain 2  score: 38.4 bits;  conditional E-value: 1.1e-13
                 --TTS--GGG-HHHHHHHHGGGHHHHHHHHHHH-TT--S-- CS
         BBE   1 aYvNyrdldlgkewgerYFggNferLvkvKtkyDPdNvFrn 41 
                 +Y N +++  + +w+ ++Fg+N++ L k+K+kyDP+ +F+ 
  EEA22023.1 513 CYQNEANFRQP-DWQNTFFGSNYNTLLKIKQKYDPNYFFYA 552
                 799********.***************************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (572 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       497  (0.0277205); expected 358.6 (0.02)
Passed bias filter:                      330  (0.0184059); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.23s 00:00:00.76 Elapsed: 00:00:00.39
# Mc/sec: 4416.74
//
Query:       EEA22024.1  [L=922]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.5e-11   41.4   0.1    1.7e-10   40.4   0.1    1.5  1  Fungal_trans  Fungal specific transcription factor domain
    1.8e-07   31.1   8.5    3.1e-07   30.4   8.5    1.3  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.013   15.4   3.0       0.25   11.3   2.0    2.7  2  Serglycin     Serglycin


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.4   0.1   2.8e-14   1.7e-10      10     200 ..     267     453 ..     260     511 .. 0.74

  Alignments for each domain:
  == domain 1  score: 40.4 bits;  conditional E-value: 2.8e-14
  Fungal_trans  10 pqfpilhkpsflpkt..ssenssksayasplll..lailalGalfsesetkesnssltsesqefiafplraeili...hedfsspssslwilqsLll 99 
                   p +p++h p+f++++  +++ +s+   +  ++l   + +a+G++  ++e+  s         + i  ++r   ++     ++++  +  + +++Ll+
    EEA22024.1 267 PSLPVIHFPTFHREYnqFWNDPSQVSLSWLAFLygCMTMAVGMFRRSMESLPSPLRDPI---DEINRFQRN-CCYcliGSNYTTVGK--YKVEALLI 357
                   899************97777778888888888866677777777777777666444444...455555553.233111112223333..5788**** PP

  Fungal_trans 100 lelyektssdralher..hhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddlwe 194
                   ++++e t   +++     ++g+a++la ++g hr+ +++ +     l+  e e+rrR+w     lD+++++++G p     +q ++++P + +d+++
    EEA22024.1 358 YATVEYTKRGNSAMSVsiILGIAIKLAMRMGYHRDAKHYDT-----LSTLEGEMRRRTWAILSQLDTLTSFQVGIPKQAQSWQSDTEIPRNINDEDI 449
                   *******99766666679********************995.....99999**************************99*************96655 PP

  Fungal_trans 195 sddase 200
                    +  + 
    EEA22024.1 450 DE--NS 453
                   44..44 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.4   8.5   5.2e-11   3.1e-07       2      33 ..      38      69 ..      37      73 .. 0.95

  Alignments for each domain:
  == domain 1  score: 30.4 bits;  conditional E-value: 5.2e-11
                S-HHHHHCT---STSSSS-HHHHHCT..HHHCCC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkkln..leCtfy 33
                +C+ Cr +K KCd+ +P C +C +++  + Ct y
  EEA22024.1 38 SCTACRYRKLKCDRTHP-CDRCTRRGdaASCT-Y 69
                9****************.*********99**9.4 PP

>> Serglycin  Serglycin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   2.0   4.1e-05      0.25      85     106 ..     101     126 ..      77     134 .. 0.51
   2 ?    1.8   0.0     0.036   2.1e+02      77     110 ..     621     651 ..     606     673 .. 0.68

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 4.1e-05
   Serglycin  85 fplsedy...sgsgsGsGsGsG.sgs 106
                 +++ ++     +sgsGsGsGsG s+s
  EEA22024.1 101 LSFAQQKkqeDESGSGSGSGSGgSNS 126
                 33333333233344444444431444 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.036
   Serglycin  77 ksqnlndvfplsedysgsgsGsGsGsGsgsgsgf 110
                  ++n nd++   e+  ++ s +G+Gs   s+ + 
  EEA22024.1 621 LFKN-NDLVNTAEQQQDTSSSAGAGS--ASERSK 651
                 4555.899999998855555555555..444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (922 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       885  (0.0493614); expected 358.6 (0.02)
Passed bias filter:                      476  (0.0265492); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.74u 0.28s 00:00:01.02 Elapsed: 00:00:00.45
# Mc/sec: 6144.97
//
Query:       EEA22025.1  [L=503]
Description: IZH family channel protein (Izh3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-59  200.4  20.2    3.8e-59  200.1  20.2    1.1  1  HlyIII    Haemolysin-III related


Domain annotation for each model (and alignments):
>> HlyIII  Haemolysin-III related
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  200.1  20.2   2.1e-63   3.8e-59       1     224 []     258     480 ..     258     480 .. 0.96

  Alignments for each domain:
  == domain 1  score: 200.1 bits;  conditional E-value: 2.1e-63
      HlyIII   1 fslhnEtlniwtHllgailfivlailllslaevken.sklakvvvlvfllgallcllcSalyHtlsihseeklrkffaklDysgIslliagsylplily 98 
                 fs++nE++niw+Hl+g+ +++ +a+++++l       +k + ++ +vf+++a++cl+cS+++Ht++ + ++k+ + fa++Dy+gIs+l+a+s+++++++
  EEA22025.1 258 FSFSNELVNIWSHLIGLFIVLSIAFYFYPLDPNFHLsTKADIMIAAVFFFAACKCLVCSTIWHTMNGIANQKVMERFACVDYTGISFLVAASIMTTEYT 356
                 789*****************999999999877666678999********************************************************** PP

      HlyIII  99 alakapkagllylslilalgvlgiisklvplfsrpearplravlfillgllgvipllhlllvltqlgeaaelalvllvlggvlylvGavfYalrvPErl 197
                 a++++p  +++y+ l+  lgv g+i+ ++p f+r+ + + r++++  +++ g  pl++ l +  +++  +  ++  +v+++++y +Ga +Ya+++PEr+
  EEA22025.1 357 AFYCEPTSRWIYILLTFSLGVGGVILPWHPTFNRSDMSWARVAFYSTMAMTGFAPLIQ-LSYSRGFE-WCLYFYAPVVKSILVYGLGACIYASQIPERW 453
                 **********************************************************.66666566.7799*************************** PP

      HlyIII 198 kpgkfdivghsHqiFHvfvvlgalfhy 224
                 +pg fd+ g sH+i+H+ v+ g+lfhy
  EEA22025.1 454 FPGLFDYCGASHNIWHIAVLGGILFHY 480
                 **************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (503 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       863  (0.0481343); expected 358.6 (0.02)
Passed bias filter:                      588  (0.032796); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.48
# Mc/sec: 3167.08
//
Query:       EEA22026.1  [L=221]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    5.7e-32  111.4  13.3    7.5e-32  111.0  13.3    1.2  1  FmiP_Thoc5   Fms-interacting protein/Thoc5
     0.0058   16.7   3.3     0.0058   16.7   3.3    2.2  2  SPATA1_C     Spermatogenesis-associated C-terminus
  ------ inclusion threshold ------
      0.012   16.1  10.3       0.23   11.9   0.4    2.3  2  DUF4200      Domain of unknown function (DUF4200)
      0.023   14.4   8.6      0.023   14.4   8.6    2.0  2  Casc1_N      Cancer susceptibility candidate 1 N-terminus
       0.21   11.5   1.1        2.8    7.8   0.1    2.2  2  CwfJ_C_1     Protein similar to CwfJ C-terminus 1
       0.62   10.2  15.2       0.56   10.3   5.0    2.4  2  Mod_r        Modifier of rudimentary (Mod(r)) protein
       0.73   10.2   9.0       0.36   11.2   6.2    2.0  2  DUF349       Domain of Unknown Function (DUF349)
        1.1    8.5  12.0        1.2    8.4   1.7    2.1  2  DUF3450      Protein of unknown function (DUF3450)
        1.9    8.5   5.1        3.6    7.6   5.1    1.6  1  DUF87        Helicase HerA, central domain
        2.6    8.2   7.1       0.55   10.3   0.3    2.4  2  Flagellin_N  Bacterial flagellin N-terminal helical region
        2.7    8.7   7.4         10    6.8   1.9    2.3  2  YabA         Initiation control protein YabA


Domain annotation for each model (and alignments):
>> FmiP_Thoc5  Fms-interacting protein/Thoc5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.0  13.3   4.6e-35   7.5e-32       1     153 [.      73     217 ..      73     221 .] 0.97

  Alignments for each domain:
  == domain 1  score: 111.0 bits;  conditional E-value: 4.6e-35
  FmiP_Thoc5   1 eLkklnrltklrikkardktaeakqkvDskhlqlqNllyEkshlekEikkcldFkskdeeieLvpeeeFyeeapeeiskpedtkkeadehelmlaRLew 99 
                 +L+ lnr++ lr++++++ taea+q++D++hlqlqNl yE +hl  Ei +c+ ++ k+ ++ L+peeeF+e  pe+         + d helm+aR+++
  EEA22026.1  73 QLRGLNRDAVLRVRETKQVTAEARQEIDRLHLQLQNLYYEQKHLMGEIAACESYDHKYLSLPLIPEEEFLELFPEHA--------SLDAHELMIARIKH 163
                 5999*******************************************************************999999........569*********** PP

  FmiP_Thoc5 100 EleqRkelaeqlkeleekkkkleqeieekkkfLssLppkLkslkkatkplqeal 153
                 E ++R++l+++ +el ++k++l +e++++k+ L +L   L+   +a+kp+q+ +
  EEA22026.1 164 EHDEREKLEQARQELLKRKQALIAENKKRKDDLANLDADLERFIDAAKPIQKIF 217
                 ***************************************************976 PP

>> SPATA1_C  Spermatogenesis-associated C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.7      0.27   4.4e+02     106     122 ..      92     108 ..      29     122 .. 0.66
   2 !   16.7   3.3   3.6e-06    0.0058       3      37 ..     161     195 ..     159     212 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.27
    SPATA1_C 106 iiaaqheidelkrkled 122
                  ++a++eid l+ +l++
  EEA22026.1  92 TAEARQEIDRLHLQLQN 108
                 23344555555554444 PP

  == domain 2  score: 16.7 bits;  conditional E-value: 3.6e-06
    SPATA1_C   3 lkrlkeerkelEerreellrkakelleqnkqkree 37 
                 +k+  +er++lE+ r+ell++++ l+++nk+++++
  EEA22026.1 161 IKHEHDEREKLEQARQELLKRKQALIAENKKRKDD 195
                 5666799***********************99976 PP

>> DUF4200  Domain of unknown function (DUF4200)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.4   0.00014      0.23      62     110 ..      79     127 ..      67     133 .. 0.91
   2 ?    7.8   4.2    0.0025       4.1      12      52 ..     155     195 ..     148     218 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00014
     DUF4200  62 aralkkaeeerklkkekeaeikklkaeietlkseiekleekleeykkYe 110
                 ++a  ++ e ++ + e  +ei +l+ ++++l  e+++l  +++ +++Y 
  EEA22026.1  79 RDAVLRVRETKQVTAEARQEIDRLHLQLQNLYYEQKHLMGEIAACESYD 127
                 678889999**************************************95 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0025
     DUF4200  12 qealeakkeeiqrleealkqreeelekkeqeleedllkfdk 52 
                 ++++++ k e+ ++e++ + r+e l++k++ + e+  + d 
  EEA22026.1 155 ELMIARIKHEHDEREKLEQARQELLKRKQALIAENKKRKDD 195
                 67888899999999999999999999999888888776664 PP

>> Casc1_N  Cancer susceptibility candidate 1 N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.1      0.23   3.8e+02     104     147 ..      56     100 ..      45     121 .. 0.54
   2 ?   14.4   8.6   1.4e-05     0.023       9      69 ..     159     220 ..     152     221 .] 0.93

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.23
     Casc1_N 104 dieevmetctlvlklieeLeelledtaeeelsekeve.eykevil 147
                 +i  + ++ +++++l+++L+ l +d+    ++ k+v+ e ++ i+
  EEA22026.1  56 TILAISKQQKILYSLLAQLRGLNRDAVLRVRETKQVTaEARQEID 100
                 566667777788888888833332322222222222201222222 PP

  == domain 2  score: 14.4 bits;  conditional E-value: 1.4e-05
     Casc1_N   9 eRlraeeeererleeerrekeereql.aaeqarrkeeleelkplleerkealeklkaearea 69 
                 +R++ e  ere+le+ r+e  +r+q+  ae ++rk+ l+ l + le++  a++ +++ ++++
  EEA22026.1 159 ARIKHEHDEREKLEQARQELLKRKQAlIAENKKRKDDLANLDADLERFIDAAKPIQKIFEKE 220
                 7*************************************************999888777665 PP

>> CwfJ_C_1  Protein similar to CwfJ C-terminus 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.1     0.077   1.3e+02      57      87 ..      85     115 ..      49     143 .. 0.69
   2 ?    7.8   0.1    0.0017       2.8      40      89 ..     146     196 ..     136     213 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.077
                 -SSTTSS-HHHHHHHHHHHHHHHHHHHHTT- CS
    CwfJ_C_1  57 isallsldeevldeirkfrkalvkmykkqdk 87 
                 + ++ ++ +e+++ei + +  l ++y +q++
  EEA22026.1  85 VRETKQVTAEARQEIDRLHLQLQNLYYEQKH 115
                 46788999999*****999999999877653 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0017
                 --.S-SSTT-EEEEESS--SSTTSS-HHHHHHHHHHHHHHHHHHHHTT--E CS
    CwfJ_C_1  40 pk.gpLssgHvliipieHisallsldeevldeirkfrkalvkmykkqdkda 89 
                 p+  +L+   ++i  i+H    +++ e++++e+ k ++al++  kk++ d+
  EEA22026.1 146 PEhASLDAHELMIARIKHEHDEREKLEQARQELLKRKQALIAENKKRKDDL 196
                 565788888899****************************99988888776 PP

>> Mod_r  Modifier of rudimentary (Mod(r)) protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   2.5     0.012        19      54      89 ..      76     118 ..      10     132 .. 0.78
   2 ?   10.3   5.0   0.00034      0.56      12      78 ..     151     218 ..     148     220 .. 0.87

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.012
       Mod_r  54 p.......eleelrselqekleelkelekefeekeqeldellq 89 
                         +++e ++ ++e+++e+++l+ +++++  e+++l+ 
  EEA22026.1  76 GlnrdavlRVRETKQVTAEARQEIDRLHLQLQNLYYEQKHLMG 118
                 1444455588999999999999999999999999999999984 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00034
       Mod_r  12 ledeeklealvk.tlpevkqlkeekeellaeneslaeknlslepeleelrselqekleelkelekefe 78 
                 l+ +e++ a++k + +e ++l+++++ell+  ++l  +n +++++l +l ++l+  ++ +k ++k fe
  EEA22026.1 151 LDAHELMIARIKhEHDEREKLEQARQELLKRKQALIAENKKRKDDLANLDADLERFIDAAKPIQKIFE 218
                 56677777777747799*************************************99999999988776 PP

>> DUF349  Domain of Unknown Function (DUF349)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0       5.3   8.7e+03      29      29 ..      90      90 ..      70     103 .. 0.52
   2 ?   11.2   6.2   0.00022      0.36      18      59 ..     165     206 ..     157     219 .. 0.72

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 5.3
      DUF349 29 e 29
                +
  EEA22026.1 90 Q 90
                1 PP

  == domain 2  score: 11.2 bits;  conditional E-value: 0.00022
      DUF349  18 kahfeeqdaereenlekKealieeaealaksttdwksatkrl 59 
                 +  +e+++++r+e l++K+ali+e ++ +++ +++++  +r+
  EEA22026.1 165 HDEREKLEQARQELLKRKQALIAENKKRKDDLANLDADLERF 206
                 567899******************999876655444433333 PP

>> DUF3450  Protein of unknown function (DUF3450)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   1.7   0.00075       1.2       9      91 ..      23     109 ..      17     120 .. 0.79
   2 ?    5.6   2.9    0.0054       8.8      37      93 ..     159     215 ..     147     219 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00075
     DUF3450   9 lasgalaatldqalkeaekavaaaaq....sqkkidklddekqellaeyralkeeleslevyneqlerlvasqeqeiasleeqieei 91 
                  +s++++++ +++l+    ++aaa+     sq+ i +++++++ l + + +l+  + ++ +  ++ +++ a+++qei++l  q++++
  EEA22026.1  23 QISANAHNQCQKLLQLLDPTNAAASGsnppSQETILAISKQQKILYSLLAQLRGLNRDAVLRVRETKQVTAEARQEIDRLHLQLQNL 109
                 44555566666666666666666554222289***************************************************9987 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0054
     DUF3450  37 kkidklddekqellaeyralkeeleslevyneqlerlvasqeqeiasleeqieeiee 93 
                 ++i++  de+++l++  ++l +++++l ++n++ ++ +a++++++++     + i++
  EEA22026.1 159 ARIKHEHDEREKLEQARQELLKRKQALIAENKKRKDDLANLDADLERFIDAAKPIQK 215
                 567777899999999999999999999999999999999999988887666666655 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   5.1    0.0022       3.6     117     203 ..      63     213 ..      27     217 .. 0.73

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0022
       DUF87 117 qrsvleealdqaka..........keekeklssdepveklleelk...................................................... 151
                 q+++l+++l+q++           ++++  + +++ + +l+ +l+                                                      
  EEA22026.1  63 QQKILYSLLAQLRGlnrdavlrvrETKQVTAEARQEIDRLHLQLQnlyyeqkhlmgeiaacesydhkylslplipeeeflelfpehasldahelmiari 161
                 555555555555554444444433333333333333333333333555566666666666666666666888888888888889999999999999996 PP

       DUF87 152 kekeelrklknqaiarlldkledllrkggsfsnsstdliallleklekegki 203
                 k + ++r++ +qa+++ll++++ l+ ++++++++ ++l+a+l+++++  ++i
  EEA22026.1 162 KHEHDEREKLEQARQELLKRKQALIAENKKRKDDLANLDADLERFIDAAKPI 213
                 66669*************************************9999888876 PP

>> Flagellin_N  Bacterial flagellin N-terminal helical region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   1.7      0.39   6.3e+02      76     119 ..      58     106 ..      21     120 .. 0.50
   2 ?   10.3   0.3   0.00034      0.55      62     122 ..     152     213 ..     148     217 .. 0.91

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.39
                  HHHHHHHHHHHH.HHHHHHHHT-T....TTS-SHHHHHHHHHHHHHHHH CS
  Flagellin_N  76 galselsdilqr.lkelavaasnd....snsdedrqslqaelqqLtdel 119
                   a+s++++il + l +l   + +     + ++++ +++++e+++L  +l
   EEA22026.1  58 LAISKQQKILYSlLAQLRGLNRDAvlrvRETKQVTAEARQEIDRLHLQL 106
                  2555555555555555555544431111223335555555565555555 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00034
                  HHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHT-TTTS-SHHHHHHHHHHHHHHHHHHH CS
  Flagellin_N  62 rnnslgisrlqtaqgalselsdilqr.lkelavaasndsnsdedrqslqaelqqLtdelnri 122
                  ++ +l i+r++ +    ++l+++ q+ lk + +  ++ ++ ++d + l+a+l++++d++  i
   EEA22026.1 152 DAHELMIARIKHEHDEREKLEQARQElLKRKQALIAENKKRKDDLANLDADLERFIDAAKPI 213
                  56788999**************************9999999****************99866 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.3     0.024        39       8      41 ..      83     116 ..      54     130 .. 0.62
   2 ?    6.8   1.9    0.0063        10      13      54 ..     157     198 ..     147     220 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.024
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        YabA   8 dkleeleeqleelleeleelkeelaelleenaeL 41 
                  +++e ++ ++e  +e+++l+ +l++l+ e ++L
  EEA22026.1  83 LRVRETKQVTAEARQEIDRLHLQLQNLYYEQKHL 116
                 3444444555555555555555555555555555 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.0063
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHXX CS
        YabA  13 leeqleelleeleelkeelaelleenaeLeleneklrerlee 54 
                 +  ++++ ++e e+l+++ +ell++ ++L +en+k ++ l++
  EEA22026.1 157 MIARIKHEHDEREKLEQARQELLKRKQALIAENKKRKDDLAN 198
                 667899999999**********************99988843 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (221 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1442  (0.0804284); expected 358.6 (0.02)
Passed bias filter:                      541  (0.0301746); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.64u 0.37s 00:00:01.01 Elapsed: 00:00:00.57
# Mc/sec: 1166.43
//
Query:       EEA22027.1  [L=241]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.1e-30  107.1   7.8    1.5e-30  106.8   7.8    1.2  1  FmiP_Thoc5   Fms-interacting protein/Thoc5
     0.0043   17.4   9.3       0.14   12.6   0.2    2.3  2  DUF4200      Domain of unknown function (DUF4200)
  ------ inclusion threshold ------
      0.013   15.6   4.2      0.013   15.6   4.2    2.1  2  SPATA1_C     Spermatogenesis-associated C-terminus
       0.09   12.5  13.2      0.027   14.2   8.6    2.0  2  Casc1_N      Cancer susceptibility candidate 1 N-terminus
       0.17   12.2   6.6       0.57   10.5   6.6    1.9  1  DUF349       Domain of Unknown Function (DUF349)
       0.91    9.6  14.8       0.65   10.1   5.0    2.4  2  Mod_r        Modifier of rudimentary (Mod(r)) protein
        1.6    8.0  12.0        1.5    8.1   1.7    2.1  2  DUF3450      Protein of unknown function (DUF3450)
        3.4    7.8   7.0       0.65   10.1   0.3    2.3  2  Flagellin_N  Bacterial flagellin N-terminal helical region
        3.7    8.3   7.3         12    6.6   1.9    2.3  2  YabA         Initiation control protein YabA


Domain annotation for each model (and alignments):
>> FmiP_Thoc5  Fms-interacting protein/Thoc5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.8   7.8   7.3e-34   1.5e-30       1     153 [.      73     237 ..      73     241 .] 0.97

  Alignments for each domain:
  == domain 1  score: 106.8 bits;  conditional E-value: 7.3e-34
  FmiP_Thoc5   1 eLkklnrltklrikkardktaeakqkvDskhlqlqNllyEkshlekEikkcldFk....................skdeeieLvpeeeFyeeapeeisk 79 
                 +L+ lnr++ lr++++++ taea+q++D++hlqlqNl yE +hl  Ei +c+ ++                     k+ ++ L+peeeF+e  pe+   
  EEA22027.1  73 QLRGLNRDAVLRVRETKQVTAEARQEIDRLHLQLQNLYYEQKHLMGEIAACESYEfvyapspfyrmyiltvdwhsHKYLSLPLIPEEEFLELFPEHA-- 169
                 5999*********************************************************************9999999***********999999.. PP

  FmiP_Thoc5  80 pedtkkeadehelmlaRLewEleqRkelaeqlkeleekkkkleqeieekkkfLssLppkLkslkkatkplqeal 153
                       + d helm+aR+++E ++R++l+++ +el ++k++l +e++++k+ L +L   L+   +a+kp+q+ +
  EEA22027.1 170 ------SLDAHELMIARIKHEHDEREKLEQARQELLKRKQALIAENKKRKDDLANLDADLERFIDAAKPIQKIF 237
                 ......569**************************************************************976 PP

>> DUF4200  Domain of unknown function (DUF4200)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.2     7e-05      0.14      62     110 ..      79     127 ..      67     129 .. 0.93
   2 !    7.6   4.2    0.0024       4.8      12      52 ..     175     215 ..     168     238 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 7e-05
     DUF4200  62 aralkkaeeerklkkekeaeikklkaeietlkseiekleekleeykkYe 110
                 ++a  ++ e ++ + e  +ei +l+ ++++l  e+++l  +++ +++Ye
  EEA22027.1  79 RDAVLRVRETKQVTAEARQEIDRLHLQLQNLYYEQKHLMGEIAACESYE 127
                 678889999***************************************8 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0024
     DUF4200  12 qealeakkeeiqrleealkqreeelekkeqeleedllkfdk 52 
                 ++++++ k e+ ++e++ + r+e l++k++ + e+  + d 
  EEA22027.1 175 ELMIARIKHEHDEREKLEQARQELLKRKQALIAENKKRKDD 215
                 67888899999999999999999999999888888776664 PP

>> SPATA1_C  Spermatogenesis-associated C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.1      0.17   3.4e+02     106     122 ..      92     108 ..      28     122 .. 0.66
   2 ?   15.6   4.2   6.3e-06     0.013       3      37 ..     181     215 ..     179     231 .. 0.87

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.17
    SPATA1_C 106 iiaaqheidelkrkled 122
                  ++a++eid l+ +l++
  EEA22027.1  92 TAEARQEIDRLHLQLQN 108
                 23344555555544444 PP

  == domain 2  score: 15.6 bits;  conditional E-value: 6.3e-06
    SPATA1_C   3 lkrlkeerkelEerreellrkakelleqnkqkree 37 
                 +k+  +er++lE+ r+ell++++ l+++nk+++++
  EEA22027.1 181 IKHEHDEREKLEQARQELLKRKQALIAENKKRKDD 215
                 5666799***********************99976 PP

>> Casc1_N  Cancer susceptibility candidate 1 N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.1      0.23   4.6e+02     104     146 ..      56      99 ..      45     119 .. 0.53
   2 ?   14.2   8.6   1.3e-05     0.027       9      69 ..     179     240 ..     172     241 .] 0.93

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.23
     Casc1_N 104 dieevmetctlvlklieeLeelledtaeeelsekeve.eykevi 146
                 +i  + ++ +++++l+++L+ l +d+    ++ k+v+ e ++ i
  EEA22027.1  56 TILAISKQQKILYSLLAQLRGLNRDAVLRVRETKQVTaEARQEI 99 
                 56666777778888888883333232222222222220122222 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 1.3e-05
     Casc1_N   9 eRlraeeeererleeerrekeereql.aaeqarrkeeleelkplleerkealeklkaearea 69 
                 +R++ e  ere+le+ r+e  +r+q+  ae ++rk+ l+ l + le++  a++ +++ ++++
  EEA22027.1 179 ARIKHEHDEREKLEQARQELLKRKQAlIAENKKRKDDLANLDADLERFIDAAKPIQKIFEKE 240
                 7*************************************************999888777665 PP

>> DUF349  Domain of Unknown Function (DUF349)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   6.6   0.00029      0.57      18      59 ..     185     226 ..     178     239 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00029
      DUF349  18 kahfeeqdaereenlekKealieeaealaksttdwksatkrl 59 
                 +  +e+++++r+e l++K+ali+e ++ +++ +++++  +r+
  EEA22027.1 185 HDEREKLEQARQELLKRKQALIAENKKRKDDLANLDADLERF 226
                 567899******************999876655444433333 PP

>> Mod_r  Modifier of rudimentary (Mod(r)) protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0   2.3     0.012        25      54      89 ..      76     118 ..      11     127 .. 0.80
   2 ?   10.1   5.0   0.00033      0.65      12      78 ..     171     238 ..     168     240 .. 0.87

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.012
       Mod_r  54 p.......eleelrselqekleelkelekefeekeqeldellq 89 
                         +++e ++ ++e+++e+++l+ +++++  e+++l+ 
  EEA22027.1  76 GlnrdavlRVRETKQVTAEARQEIDRLHLQLQNLYYEQKHLMG 118
                 144445558899999999***************9999999985 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00033
       Mod_r  12 ledeeklealvk.tlpevkqlkeekeellaeneslaeknlslepeleelrselqekleelkelekefe 78 
                 l+ +e++ a++k + +e ++l+++++ell+  ++l  +n +++++l +l ++l+  ++ +k ++k fe
  EEA22027.1 171 LDAHELMIARIKhEHDEREKLEQARQELLKRKQALIAENKKRKDDLANLDADLERFIDAAKPIQKIFE 238
                 56677777777747799*************************************99999999988776 PP

>> DUF3450  Protein of unknown function (DUF3450)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   1.7   0.00075       1.5       9      91 ..      23     109 ..      17     120 .. 0.79
   2 ?    5.3   2.9    0.0051        10      37      93 ..     179     235 ..     167     239 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00075
     DUF3450   9 lasgalaatldqalkeaekavaaaaq....sqkkidklddekqellaeyralkeeleslevyneqlerlvasqeqeiasleeqieei 91 
                  +s++++++ +++l+    ++aaa+     sq+ i +++++++ l + + +l+  + ++ +  ++ +++ a+++qei++l  q++++
  EEA22027.1  23 QISANAHNQCQKLLQLLDPTNAAASGsnppSQETILAISKQQKILYSLLAQLRGLNRDAVLRVRETKQVTAEARQEIDRLHLQLQNL 109
                 44555566666666666666666554222289***************************************************9987 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0051
     DUF3450  37 kkidklddekqellaeyralkeeleslevyneqlerlvasqeqeiasleeqieeiee 93 
                 ++i++  de+++l++  ++l +++++l ++n++ ++ +a++++++++     + i++
  EEA22027.1 179 ARIKHEHDEREKLEQARQELLKRKQALIAENKKRKDDLANLDADLERFIDAAKPIQK 235
                 567777899999999999999999999999999999999999988887666666655 PP

>> Flagellin_N  Bacterial flagellin N-terminal helical region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   1.7      0.36   7.2e+02      76     119 ..      58     106 ..      21     120 .. 0.50
   2 ?   10.1   0.3   0.00032      0.65      62     122 ..     172     233 ..     168     237 .. 0.91

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.36
                  HHHHHHHHHHHH.HHHHHHHHT-T....TTS-SHHHHHHHHHHHHHHHH CS
  Flagellin_N  76 galselsdilqr.lkelavaasnd....snsdedrqslqaelqqLtdel 119
                   a+s++++il + l +l   + +     + ++++ +++++e+++L  +l
   EEA22027.1  58 LAISKQQKILYSlLAQLRGLNRDAvlrvRETKQVTAEARQEIDRLHLQL 106
                  2455555555555555555544431111223335555555555555555 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00032
                  HHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHT-TTTS-SHHHHHHHHHHHHHHHHHHH CS
  Flagellin_N  62 rnnslgisrlqtaqgalselsdilqr.lkelavaasndsnsdedrqslqaelqqLtdelnri 122
                  ++ +l i+r++ +    ++l+++ q+ lk + +  ++ ++ ++d + l+a+l++++d++  i
   EEA22027.1 172 DAHELMIARIKHEHDEREKLEQARQElLKRKQALIAENKKRKDDLANLDADLERFIDAAKPI 233
                  56788999**************************9999999****************99866 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.3     0.025        50       7      41 ..      82     116 ..      54     126 .. 0.61
   2 ?    6.6   1.9     0.006        12      13      54 ..     177     218 ..     167     240 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.025
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        YabA   7 fdkleeleeqleelleeleelkeelaelleenaeL 41 
                 + +++e ++ ++e  +e+++l+ +l++l+ e ++L
  EEA22027.1  82 VLRVRETKQVTAEARQEIDRLHLQLQNLYYEQKHL 116
                 33444445555555555555555555555555555 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.006
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHXX CS
        YabA  13 leeqleelleeleelkeelaelleenaeLeleneklrerlee 54 
                 +  ++++ ++e e+l+++ +ell++ ++L +en+k ++ l++
  EEA22027.1 177 MIARIKHEHDEREKLEQARQELLKRKQALIAENKKRKDDLAN 218
                 667889999999**********************99988843 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (241 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1541  (0.0859501); expected 358.6 (0.02)
Passed bias filter:                      636  (0.0354733); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.55u 0.33s 00:00:00.88 Elapsed: 00:00:00.49
# Mc/sec: 1477.39
//
Query:       EEA22028.1  [L=1000]
Description: GPI transamidase component PIG-S, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   9.7e-179  595.5   3.3   9.7e-179  595.5   3.3    1.4  2  PIG-S     Phosphatidylinositol-glycan biosynthesis class S pr
  ------ inclusion threshold ------
       0.29   11.9   3.9       0.28   12.0   2.0    2.0  1  DUF4512   Domain of unknown function (DUF4512)


Domain annotation for each model (and alignments):
>> PIG-S  Phosphatidylinositol-glycan biosynthesis class S protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.6   1.0      0.83   7.5e+03     122     132 ..     168     178 ..     133     209 .. 0.38
   2 !  595.5   3.3  1.1e-182  9.7e-179       1     510 [.     479     989 ..     479     991 .. 0.95

  Alignments for each domain:
  == domain 1  score: -4.6 bits;  conditional E-value: 0.83
       PIG-S 122 tssaelskesk 132
                 ts++++s+  +
  EEA22028.1 168 TSTISISDTAP 178
                 11122222222 PP

  == domain 2  score: 595.5 bits;  conditional E-value: 1.1e-182
       PIG-S   1 afvlvvlllGlPlWwktTtiyRapLPleeiealadgkacrvtfplevvvdasslpeeeaekllkevqqalddllekkefsletrwslrlklseseeqee 99 
                 af++v++++GlP+Ww+tT++yRa+LPl+e++++a+gkac+++fple+v++++s++ +ea++ll+++q+alddl+   ef     ++lrlkl++++e++e
  EEA22028.1 479 AFWVVIIFFGLPMWWRTTSVYRASLPLDEMMSWAEGKACKPEFPLEIVLRTPSTSMAEAQSLLRTTQHALDDLN---EFPV---HHLRLKLANHTETTE 571
                 79************************************************************************...9998...********9999888 PP

       PIG-S 100 .......seseeeedgaltvrllpeedlstssaelskeskaldvvyppnsv...ssssdklsafvaeelvelfleeeeealisasksellsts...... 182
                         e+e+++++al+v+l+p+e   t+++el+++ +++d++ypp+++   +s++++l +f+a e+++lf ee  +a+i+    ++l +s      
  EEA22028.1 572 nnkldidIETEDNSNAALVVNLIPSE-IATPTSELHSHAPRIDIWYPPSQLssvTSTTSPLITFIAGEIQKLFNEE--KATIA----YILGQSnsalas 663
                 99****9778899*************.9999********************554449*******************..66666....344333445566 PP

       PIG-S 183 .............krttrsikysptyhLsfsllnedpepssWdieaaleeylsplldaLspianftvetqvqyyapls...lkpef.eevaavvlskdd 264
                              kr  rs+ky++tyhLsfsl++++++pssW+ie+a++ey+ pllda+spi+nf+++tqvq+ya++s    +pe+ e++++++l+++d
  EEA22028.1 664 sfprggqlaelvsKRVGRSLKYAETYHLSFSLFTPGSQPSSWEIENAIQEYFVPLLDAFSPISNFSIDTQVQLYASFSptsPHPEYdEGSQKWTLKEED 762
                 7***********9999**************************************************************988888999999********* PP

       PIG-S 265 LssfvnaaEwslsssisssptlnFvvyvPsksespllikdstgeqsktnsfliPqWGgvvilnppaeekksegsssaelseeelkevmevFssqLrsLL 363
                 Lssf+naaEw+ls+ i+s+pt+nFv+yvP++++spl++k++  ++    s+++PqWGgvvi+nppa+  ++   ++ +l++e+lk+++ +Fs+qL++LL
  EEA22028.1 763 LSSFINAAEWPLSPGIGSGPTINFVLYVPAATQSPLVVKENL-AT----SWIVPQWGGVVIVNPPATPGDD--INPPHLAKESLKPALLTFSHQLLTLL 854
                 ****************************************99.66....******************9777..67************************ PP

       PIG-S 364 GlpseekleessspaslpllreweldtlkrrrtlelllsassTLgSLarLveslpnivIpdeVaedVesalellesaldaleegrleealasareaeal 462
                 G+p         +p+slpl    +l+t +r+r+++lllsassT+gSLarL++sl++i+Ip++Va++V ++l++l+s+++ l+eg++++alasar+ae++
  EEA22028.1 855 GTP--------ATPSSLPL----RLQTSIRTRAATLLLSASSTMGSLARLTQSLSSIPIPRNVASSVLTTLSHLSSTCQLLREGKFAAALASARIAEKE 941
                 ***........57889999....**********************************************************99**************** PP

       PIG-S 463 aerAFFdpsmlgqlYFPdEhkvAVYlPLlgPvlvplllgllkelkelk 510
                 ae++FF++sm+gq+YFPdEhk+AVYlPLlgP++vpl++gll+e+k+l+
  EEA22028.1 942 AEKSFFEKSMVGQMYFPDEHKIAVYLPLLGPIGVPLVMGLLREVKNLV 989
                 *********************************************986 PP

>> DUF4512  Domain of unknown function (DUF4512)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   2.0   3.1e-05      0.28      18      91 ..      86     161 ..      84     177 .. 0.65

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 3.1e-05
     DUF4512  18 fvePivlry..inPwekkdaegnvikagpefPfeckGGvcPfvpgskksdaksdada..eeseksesatttataaste 91 
                 f+ePi  +   +n      a+ +  k + + P  c  G cPf + +  +++++  d+  +++++s sa+ttat+a t+
  EEA22028.1  86 FIEPITCNVqaMNATANPTAPIQSTKLSDDLP-TCANGCCPF-GYTCAKNTTCVLDSstSTTTDSGSASTTATSAATT 161
                 77777654311555566667777778888999.899******.55555666665555124555555555555555443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1000 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1088  (0.0606838); expected 358.6 (0.02)
Passed bias filter:                      515  (0.0287244); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.83u 0.28s 00:00:01.10 Elapsed: 00:00:00.43
# Mc/sec: 7007.47
//
Query:       EEA22029.1  [L=291]
Description: Fe superoxide dismutase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-17   63.2   0.0    3.8e-08   33.4   0.0    2.5  3  Sod_Fe_C  Iron/manganese superoxide dismutases, C-terminal do


Domain annotation for each model (and alignments):
>> Sod_Fe_C  Iron/manganese superoxide dismutases, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0      0.41   7.3e+03      35      55 ..      59      81 ..      45      91 .. 0.63
   2 !   27.0   0.0   2.1e-10   3.7e-06       4      60 ..     129     186 ..     127     198 .. 0.89
   3 !   33.4   0.0   2.1e-12   3.8e-08      62     101 ..     234     274 ..     213     275 .. 0.83

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 0.41
                EEEEEEETT..TEEEEEEEETTT CS
    Sod_Fe_C 35 wawLvldkk..kkLeivttknqd 55
                +aw  +++   +kL+++t++ +d
  EEA22029.1 59 FAWTQYQSLlvDKLNLMTQDTAD 81
                55666655444566666655555 PP

  == domain 2  score: 27.0 bits;  conditional E-value: 2.1e-10
                 HHHHHHHHHHSSHHHHHHHHHHHHHHSSSSEEEEEEEETT.TEEEEEEEETTTBGGGG CS
    Sod_Fe_C   4 elaeaieedfgslekfkkefkaaalavfgsGwawLvldkk.kkLeivttknqdnplvk 60 
                 +la++++++  s e++k++f a+a a+fg G++wLv +k+ + L+i++t n+ +p+ +
  EEA22029.1 129 KLASDMNDSASSPESLKQDFLATASAQFGPGFVWLVSQKQnGLLRILSTYNAGTPYPE 186
                 79999999*****************************9884689********998765 PP

  == domain 3  score: 33.4 bits;  conditional E-value: 2.1e-12
                 TCEEEEEE-SGGGTHHHH.TT-HHHHHHHHGGGBBHHHHHH CS
    Sod_Fe_C  62 akplLalDvwehAYyldy.qnkradYieafwnvvnWkevee 101
                  +plL+++ weh +++d+    + +Y+e++w+ v+W++ve+
  EEA22029.1 234 LTPLLCVNTWEHVWMMDHgISGKDEYLERWWDRVDWNAVED 274
                 34****************55789***************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (291 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       299  (0.0166769); expected 358.6 (0.02)
Passed bias filter:                      254  (0.014167); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 2108.10
//
Query:       EEA22030.1  [L=228]
Description: sreptomyces cyclase/dehydrase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.8e-21   74.5   0.0      2e-20   73.3   0.0    1.6  1  Polyketide_cyc   Polyketide cyclase / dehydrase and lipid tra
     0.0027   18.0   0.0     0.0064   16.8   0.0    1.6  1  Polyketide_cyc2  Polyketide cyclase / dehydrase and lipid tra


Domain annotation for each model (and alignments):
>> Polyketide_cyc  Polyketide cyclase / dehydrase and lipid transport
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.3   0.0   2.2e-24     2e-20       1     130 []      69     217 ..      69     217 .. 0.89

  Alignments for each domain:
  == domain 1  score: 73.3 bits;  conditional E-value: 2.2e-24
                     ESS-HHHHHHHHTTTGGCCSCCCCEEEEEE.SSSEE......E..EEECSTTSSCEEEEEEEEEEETTT...............EEECTTCCCCC CS
  Polyketide_cyc   1 vpapadqvyalvadvesypeflphcssvevleeaes...glsa..dlevgfggltesftarvtldppee...............itfklvegdfk 75 
                     +p p++ +y+++a vesy++flp++  ++v++++++          l+vg+g++te+ft+rv +d+++                      eg+f+
      EEA22030.1  69 LPFPPSPLYDIIASVESYSDFLPFLGASTVTARDQNtgyP--SqaFLTVGYGPFTETFTSRVICDRDNWvveaksgggvgkdgkPIPGADEGLFS 161
                     588********************************96553..14489*******************999**************856677889*** PP

                     EEEEEEEECTECCEEE..CEEEEEEEEEEEE-SSCHHHHHHHHHHHHHHHHHHHHHH CS
  Polyketide_cyc  76 slegkWtieslppnsg..gtrtkvalevdfkfaspllgalvgqvaervldellaale 130
                     +l++kW++++l + +g    +t+v+le++f+f  p+  a++  v+++v+  +++a+e
      EEA22030.1 162 HLSTKWELVPLTS-KGtgVVETEVRLEIQFRFENPMHTAMMSAVEDKVAGVMIEAFE 217
                     ************8.3334556788888889999**********************97 PP

>> Polyketide_cyc2  Polyketide cyclase / dehydrase and lipid transport
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.0   7.2e-07    0.0064       3     129 ..      62     218 ..      61     225 .. 0.61

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 7.2e-07
                      EEEEEEEESS-HHHHHHHHTTTTGGGGT-TTEEEEECSESTSSS....TTTEEEEECCCSSEEEEEEEEE...ETTTTEEEEEE.......E.. CS
  Polyketide_cyc2   3 kvtvsvviaappekVwalvsdfenwprWhpevarveleggggpa....rgvegtvrvggrgtvreelvev...dpegrllsyri.......v.. 80 
                      ++++s++ + pp   ++++++ e+++   p++  ++++ +++++    +     +  +g+g+ +e+++ +   d  +  +  ++          
       EEA22030.1  62 TLHASRTLPFPPSPLYDIIASVESYSDFLPFLGASTVTARDQNTgypsQ---AFL-TVGYGPFTETFTSRvicD--RDNWVVEAksgggvgKdg 149
                      578999***************************9998876666544321...233.334477888888874442..333333333344433033 PP

                      ......SSS-TSE.EEEEEEEE...CCET...EEEEEEEEEEE.E--TT--.......HHHHHHHHHHH CS
  Polyketide_cyc2  81 .....kpvpvany.vatwtvtp...dggg...trvtwtgefda.gplggpf.......ekpaaakavkg 129
                           ++ +++++ ++ w++ p    g+g   t+v+ +++f++ +p    +       +++++ +a+++
       EEA22030.1 150 kpipgADEGLFSHlSTKWELVPltsKGTGvveTEVRLEIQFRFeNPMHTAMmsavedkVAGVMIEAFEK 218
                      46689888988884666*****55444559988888777777643333222111121123334444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (228 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       316  (0.0176251); expected 358.6 (0.02)
Passed bias filter:                      295  (0.0164538); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 1515.03
//
Query:       EEA22031.1  [L=649]
Description: hypothetical protein PMAA_058100 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.7e-07   29.3   7.3    1.7e-06   28.0   7.3    1.7  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.0   7.3   9.4e-11   1.7e-06       2      33 ..     213     244 ..     212     249 .. 0.93

  Alignments for each domain:
  == domain 1  score: 28.0 bits;  conditional E-value: 9.4e-11
                 S-HHHHHCT---STSSSS-HHHHHCTHHHCCC CS
     Zn_clus   2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfy 33 
                 +C +C+ ++vKCd+ +PaC++C + + +C  y
  EEA22031.1 213 GCRTCKVRRVKCDETRPACGRCTSTGRTCDGY 244
                 6****************************755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (649 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       655  (0.036533); expected 358.6 (0.02)
Passed bias filter:                      520  (0.0290033); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.64u 0.25s 00:00:00.89 Elapsed: 00:00:00.44
# Mc/sec: 4387.52
//
Query:       EEA22032.1  [L=306]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.5e-17   61.7  12.8    9.5e-17   61.1  12.8    1.2  1  UbiA      UbiA prenyltransferase family


Domain annotation for each model (and alignments):
>> UbiA  UbiA prenyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.1  12.8   5.3e-21   9.5e-17       5     242 ..      49     283 ..      46     296 .. 0.80

  Alignments for each domain:
  == domain 1  score: 61.1 bits;  conditional E-value: 5.3e-21
        UbiA   5 alvglalaaggspdl.llllllllgtllaaaaanalNdyfDreiDadmertpnRPlvsGrispkealifaivllilgllll.alllnpltallgllall 101
                 +l++l++   +   + +++  ++l ++l+  +  + N++  +++D+   ++p+RP++sG+ + ++a+i +++l +l l+ + +l++  +t+l+++ +++
  EEA22032.1  49 TLASLLYRKASAEEIySVIPYAFLYGFLYLYSFVVANQIDGVNEDKV--NKPDRPIASGATTLRAAKIRWTILTLLYLGYSfYLGVEKPTLLWIATTIA 145
                 5666666666666656778889999**********************..****************************9999788888999888888885 PP

        UbiA 102 lyvvYtglrlKrrtllgtvvggiafglppllgwaavtgslsllalllalavflltwaialandlrdregDrkagiktlpvvlGrkaaril.lalllavl 199
                      + l +  +++ ++ + g+ +   +++gwa+ + s  + + ++  +++ + w+i l  dlrd+ gD+++g+ t+p+++G+  +ri+ +a +++  
  EEA22032.1 146 H----NFLGFANFGPTKDGCMGAGCIAQLTAGWAIGGSSPEMGWDWIKYITLYMLWPIPLQ-DLRDVPGDKAVGRLTTPILMGDTISRIYiSAGICVSQ 239
                 4....425889************************9999999999999999*********8.**************************96533333333 PP

        UbiA 200 lla.llllllalllllylllalllaalallraarlvrrrdakka 242
                 +l+  + +l + +   + +l++lla++ l++ +rl+++r+  ++
  EEA22032.1 240 YLLvRYRILEYRYDISTIILSALLAVMSLAVVVRLFAWRTVTAD 283
                 33342333344444455555556666666666667666665555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (306 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       564  (0.0314574); expected 358.6 (0.02)
Passed bias filter:                      269  (0.0150036); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 2006.56
//
Query:       EEA22033.1  [L=422]
Description: actin binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      3e-15   56.8   0.1    1.6e-14   54.5   0.0    2.1  2  Methyltransf_12  Methyltransferase domain
      4e-14   53.1   0.0    1.6e-13   51.2   0.0    2.1  1  Methyltransf_25  Methyltransferase domain
    9.2e-14   51.6   0.3    1.6e-13   50.8   0.0    1.6  2  Methyltransf_23  Methyltransferase domain
    1.2e-12   48.3   0.1    8.1e-12   45.6   0.0    2.4  3  Methyltransf_11  Methyltransferase domain
    8.9e-10   38.6   0.0    1.6e-09   37.7   0.0    1.6  1  Methyltransf_31  Methyltransferase domain
    1.5e-06   27.7   0.0    3.3e-06   26.6   0.0    1.5  1  Ubie_methyltran  ubiE/COQ5 methyltransferase family
    0.00011   22.1   0.9      0.011   15.6   0.1    2.6  2  Methyltransf_8   Hypothetical methyltransferase
    0.00099   18.4   0.0     0.0018   17.6   0.0    1.4  1  DUF3419          Protein of unknown function (DUF3419)
      0.001   18.3   0.0       0.12   11.5   0.0    2.4  2  NNMT_PNMT_TEMT   NNMT/PNMT/TEMT family
     0.0018   19.3   0.0      0.006   17.6   0.0    1.9  1  Methyltransf_24  Methyltransferase domain
      0.002   18.2   0.2      0.066   13.2   0.0    2.2  2  Methyltransf_32  Methyltransferase domain
     0.0097   15.5   0.0      0.018   14.6   0.0    1.4  1  MTS              Methyltransferase small domain
  ------ inclusion threshold ------
       0.75    9.9   9.6       0.18   11.9   6.0    1.8  2  DUF3408          Protein of unknown function (DUF3408)


Domain annotation for each model (and alignments):
>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.5   0.0   1.1e-17   1.6e-14       1      98 [.     139     251 ..     139     252 .. 0.91
   2 ?   -0.9   0.1         2   2.8e+03      34      77 ..     323     366 ..     304     381 .. 0.54

  Alignments for each domain:
  == domain 1  score: 54.5 bits;  conditional E-value: 1.1e-17
  Methyltransf_12   1 LeiGcGtGsllrallekl..pdieytgvDispsaiedakeklakrennnnnnvelealdlldldgg...............ssfDlvvasnvlh 77 
                      Le+G+G G+++++l +++  +++++ ++D+s++a+    + +++ e +n ++++ e+ d+ +++++               +s+D+v++++ ++
       EEA22033.1 139 LEVGAGAGNTAFPLINNNenEELKVFACDYSKNAV----KVMRESEHYNEKFMRAEVWDVTSDEEEidgeikssmppgveeGSVDVVILIFIMS 228
                      8*****************99***************....6666677777778888888877777778889************************ PP

  Methyltransf_12  78 hl..kdirevldnirklLkpgGr 98 
                      +l  ++++++l+ni+++LkpgG 
       EEA22033.1 229 ALapDQWNAALRNIHRVLKPGGL 251
                      ***99999**************7 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 2
  Methyltransf_12  34 edakeklakrennnnnnvelealdlldldggssfDlvvasnvlh 77 
                      e a++k  ++ + ++++ + e +d  +++++++ D+  a++vl+
       EEA22033.1 323 ELAENKEEQQTETSTEKTTEESIDKNQEEQEQTEDTEGAFEVLN 366
                      44555555555555555555555544444445555555555555 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.2   0.0   1.1e-16   1.6e-13       1      97 []     138     250 ..     138     250 .. 0.78

  Alignments for each domain:
  == domain 1  score: 51.2 bits;  conditional E-value: 1.1e-16
                      EEEET-TTSHHHHHHHCTS.T.SSEEEEEESSHHHHHHHHHHHHHTTT..TEEE..EESBCCGBS..........SSTTTEEEEEEESTGGGSS CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrl.g.kakvtgvDiseemleaareraeeegl..nvef..vqgdaedlp..........fedgsfDlvvssgalhhls 78 
                      vL++G+G G++++ l ++  + + kv ++D+s+++++ +re  + ++   ++e+  v+ d e+++           e+gs+D+v++++ ++ l 
       EEA22033.1 138 VLEVGAGAGNTAFPLINNNeNeELKVFACDYSKNAVKVMRESEHYNEKfmRAEVwdVTSDEEEIDgeikssmppgVEEGSVDVVILIFIMSALA 231
                      9****************986369*****************776654442433333333333333233333333666**********999***** PP

                      HHHHHHHHHHHHHHEEEEE CS
  Methyltransf_25  79 dedlekalkeiarvLkpgG 97 
                      ++++ +al++i+rvLkpgG
       EEA22033.1 232 PDQWNAALRNIHRVLKPGG 250
                      ******************9 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.8   0.0   1.2e-16   1.6e-13      20     155 ..     132     298 ..      77     301 .. 0.76
   2 ?   -3.2   0.1       4.7   6.5e+03      61      71 ..     329     353 ..     305     365 .. 0.49

  Alignments for each domain:
  == domain 1  score: 50.8 bits;  conditional E-value: 1.2e-16
  Methyltransf_23  20 lraggrvLdiGcGtG.illevl...rengfsvtgvDlspeaveiae.....kakkaqkdqfdeqeaae...................pqgkfdl 85 
                         ++ vL++G+G G +  +++   + +  +v + D s +av+  +     +      + ++++ +++                   ++g+ d+
       EEA22033.1 132 GAGPKVVLEVGAGAGnTAFPLInnnENEELKVFACDYSKNAVKVMResehyN-----EKFMRAEVWDVtsdeeeidgeikssmppgvEEGSVDV 220
                      344669*********445566665333356*************998554443.....333333433333333355566666666666777**** PP

  Methyltransf_23  86 Ivlrevlehvp.d.ppellrqiatllkpgGylllseplasl......kedrllldwlylvpagrhisffsarslkell 155
                      ++l++ +  +  d + ++lr+i++ lkpgG++l++++++ +      k +r l ++ y + +g+ ++ff++++l++++
       EEA22033.1 221 VILIFIMSALApDqWNAALRNIHRVLKPGGLVLFRDYGRGDlaqvrfKKERYLSENFYVRGDGTRVYFFDEEELRQMW 298
                      **********9637************************9886666655666666688888888************986 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 4.7
  Methyltransf_23  61 e..............kakkaqkdqf 71 
                      e              +++k+q +q+
       EEA22033.1 329 EeqqtetstektteeSIDKNQEEQE 353
                      0444444444443334444444444 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0       3.6     5e+03      63      83 ..      51      73 ..      48      75 .. 0.76
   2 !   45.6   0.0   5.9e-15   8.1e-12       1      96 []     139     254 ..     139     254 .. 0.84
   3 ?   -2.4   0.0       5.8   8.1e+03      18      43 ..     306     331 ..     294     351 .. 0.59

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 3.6
                     EEEEEES-CCC-..CCHHHHHHH CS
  Methyltransf_11 63 Dlvvssevlhhv..edpekalke 83
                     D v+s+++++hv  ++  ka +e
       EEA22033.1 51 DDVFSYNAWDHVetDEDYKAYAE 73
                     6799********76666666665 PP

  == domain 2  score: 45.6 bits;  conditional E-value: 5.9e-15
                      EEET-TTSHHHHHHHHTT....SEEEEEES-HHHHHHHHHHCCHHT-....EEEE.........TTEECCC.TS..S-TT-EEEEEEES-CCC- CS
  Methyltransf_11   1 LdvGcGtGrlaealakrg....arvvgvDlskemlklakekaseegl....kvef.........vvadaek.lp..fednsfDlvvssevlhhv 74 
                      L+vG+G+G  a +l ++      +v+++D+sk+++k+ +e  + ++     +  +         + +++++ +p  +e++s+D+v++ + +  +
       EEA22033.1 139 LEVGAGAGNTAFPLINNNeneeLKVFACDYSKNAVKVMRESEHYNEKfmraE--VwdvtsdeeeIDGEIKSsMPpgVEEGSVDVVILIFIMSAL 230
                      89*************55566799***************98888887767550..2455666666777777556558****************** PP

                      ..CCHHHHHHHHHHHEEEEEEEEE CS
  Methyltransf_11  75 ..edpekalkeiaRvLkpgGllvi 96 
                        +++++al++i+RvLkpgGl+++
       EEA22033.1 231 apDQWNAALRNIHRVLKPGGLVLF 254
                      999*****************9976 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 5.8
                      TSEEEEEES-HHHHHHHHHHCCHHT- CS
  Methyltransf_11  18 garvvgvDlskemlklakekaseegl 43 
                      g   v+ D+s+e ++  + + ++e+ 
       EEA22033.1 306 GLPMVNNDISTENTDSPELAENKEEQ 331
                      55567778888888554444444432 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.7   0.0   1.2e-12   1.6e-09       5     113 ..     136     258 ..     133     356 .. 0.79

  Alignments for each domain:
  == domain 1  score: 37.7 bits;  conditional E-value: 1.2e-12
  Methyltransf_31   5 lrvlDlGCGtGeltfelae.elgpkaevvGiDiseeaielArenaqklgldnveFeqgdiee.leklled.............ekfDlilsnev 83 
                      ++vl++G+G+G+ +f l   + +++ +v+  D+s++a++++re +++ + + ++ e+ d+++  e+   d              ++D+++   +
       EEA22033.1 136 KVVLEVGAGAGNTAFPLINnNENEELKVFACDYSKNAVKVMRE-SEHYNEKFMRAEVWDVTSdEEEI--DgeikssmppgveeGSVDVVILIFI 226
                      689***************988889999****************.56666668888887777755543..34567777778888*****999766 PP

  Methyltransf_31  84 l.naladp.dkileeiervlkpggilliedpr 113
                      + ++ +d+ +++l++i+rvlkpgg +l +d+ 
       EEA22033.1 227 MsALAPDQwNAALRNIHRVLKPGGLVLFRDYG 258
                      675555554899***************99987 PP

>> Ubie_methyltran  ubiE/COQ5 methyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.6   0.0   2.4e-09   3.3e-06      43     165 ..     127     268 ..     104     281 .. 0.69

  Alignments for each domain:
  == domain 1  score: 26.6 bits;  conditional E-value: 2.4e-09
                      --S--TT...EEEEES-TT-HHHHHHHHHHHH.HHEEEEEES-HHHHHHHHHHHH.HHTSS............TEEEEE--TTT-TTS-T-EEE CS
  Ubie_methyltran  43 vavkrga...kvlDvagGtgDlafklsdsvge.kgkvvvlDinenmLkvgekklk.eegki............nieflqanaeeLpfeddsfDv 119
                      + +k+ga    vl+v +G+g+ af l ++ ++ + kv  +D+++n +kv ++  + +e ++            +i+    +++    e++s Dv
       EEA22033.1 127 EVTKQGAgpkVVLEVGAGAGNTAFPLINNNENeELKVFACDYSKNAVKVMRESEHyNEKFMraevwdvtsdeeEIDGEIKSSMPPGVEEGSVDV 220
                      444444444489*************9987765156***********9998765441455555533333343333444444444445789***** PP

                      EEEES-GGG-.S-H.HHHHHHHHHHEEEEEEEEEEEE----SHHHHHH CS
  Ubie_methyltran 120 vtvsfGlrnv.tDk.lkaLkeayrvlkpGGrlvvlefskvelpllsqa 165
                      v + f +  + +D+ + aL++++rvlkpGG ++  ++ +  l  +++ 
       EEA22033.1 221 VILIFIMSALaPDQwNAALRNIHRVLKPGGLVLFRDYGRGDLAQVRFK 268
                      ******998735653679************999887777766666655 PP

>> Methyltransf_8  Hypothetical methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.1   7.8e-06     0.011     114     154 ..     207     252 ..      76     257 .. 0.82
   2 ?   -3.5   0.1       5.6   7.7e+03     170     214 ..     342     386 ..     335     391 .. 0.71

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 7.8e-06
                     TS-S..--TT-EEEEE..EES-.--SS-HHHHHHHHHHHEEEEEEE CS
  Methyltransf_8 114 akvP..ledesvdvav..fcls.lmgtnladflkeanrvlkvGGll 154
                     + +P  +e++svdv++  f +s l  ++++  l++++rvlk+GGl+
      EEA22033.1 207 SSMPpgVEEGSVDVVIliFIMSaLAPDQWNAALRNIHRVLKPGGLV 252
                     556645799****986225666244578****************96 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 5.6
                     HHHHHCTTEEEEEEE--STTEEEEEEEE-SSS-TT---GG----- CS
  Methyltransf_8 170 araltklGfevkskdlsnkqfvlfefkkvekkgkkrelglklkpc 214
                     ++ ++k   e+++++ ++  f ++++ k ++    r+ +lk+  c
      EEA22033.1 342 EESIDKNQEEQEQTEDTEGAFEVLNLGKDQRLLVNRQRKLKMYRC 386
                     555666666777778888888888888888777777777777666 PP

>> DUF3419  Protein of unknown function (DUF3419)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   1.3e-06    0.0018     292     363 ..     213     284 ..     165     302 .. 0.89

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 1.3e-06
     DUF3419 292 lkkksltravllDhmDWledeeleeeiqelnralkpggrvllRsaaeepwyakrfeklgFkvkavaaresge 363
                 ++++s+++++l+ +m+ l+ ++ ++ +++++r+lkpgg vl+R  ++    + rf+k+ + +++  +r +g+
  EEA22033.1 213 VEEGSVDVVILIFIMSALAPDQWNAALRNIHRVLKPGGLVLFRDYGRGDLAQVRFKKERYLSENFYVRGDGT 284
                 6789**************99************************************9999999888887665 PP

>> NNMT_PNMT_TEMT  NNMT/PNMT/TEMT family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0     0.014        19      17      91 ..      95     172 ..      82     199 .. 0.77
   2 !   11.5   0.0   9.1e-05      0.12     157     196 ..     216     253 ..     171     257 .. 0.77

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.014
                     -HHHHHHHHCSTTTTSTC.CCCHHHHHHHHHHHHHHTSSS-ECEEEEET-..TT--GGGTTGGGTEC.EEEEEESSHHH CS
  NNMT_PNMT_TEMT  17 epraYLekyykkasedaa.eeqvvlfaLknllqtlatgekkgdtllDiGa..GPTvyqllsarevak.eitlsDyldqN 91 
                     +p ++ + +yk ++++   +++ ++   ++l++  + ++   +++l++Ga  G T + l+   e+ + ++   Dy+++ 
      EEA22033.1  95 NPAKFWDRFYKNHNQNFFkDRKWLRQEFPVLAEVTK-QGAGPKVVLEVGAgaGNTAFPLINNNENEElKVFACDYSKNA 172
                     7999999*********99455689999999998877.666689999987611578888888777655467777887655 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 9.1e-05
                     ..EEEEEEESSHHHH-SSHHHHHHHHHHHHTTEEEEEEEE CS
  NNMT_PNMT_TEMT 157 kkadvvvtifcleaacedleeylralrnlasllkpGGhlv 196
                       +dvv+ if + a ++d  ++ +alrn+ ++lkpGG ++
      EEA22033.1 216 GSVDVVILIFIMSALAPD--QWNAALRNIHRVLKPGGLVL 253
                     359*********999986..89***************876 PP

>> Methyltransf_24  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   4.3e-06     0.006       1     106 []     139     257 ..     139     257 .. 0.76

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 4.3e-06
  Methyltransf_24   1 vEiGvysGvstlwllralrrngagrlvavdhdpgaeeaaalare..aglddr..vrlikads........eealasla........agsiD... 71 
                      +E+G+ +G++++ l    ++ +  +++a+d  +   +a +++re  ++ +++  ++++  +s               +        +gs+D   
       EEA22033.1 139 LEVGAGAGNTAFPLINNNENEEL-KVFACDYSK---NAVKVMREseHYNEKFmrAEVWDVTSdeeeidgeI------KssmppgveEGSVDvvi 222
                      79*******99999987776666.9********...88888888653333324478887777544444330......14444555599999777 PP

  Methyltransf_24  72 llfiDgghaaeavledleallprlapggvvlfdDi 106
                      l+fi    a ++  ++l++++++l+pgg+vlf D+
       EEA22033.1 223 LIFIMSALAPDQWNAALRNIHRVLKPGGLVLFRDY 257
                      788888888899999*****************997 PP

>> Methyltransf_32  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.2   0.0   4.8e-05     0.066      21      90 ..     130     197 ..     120     238 .. 0.78
   2 ?    2.6   0.4     0.085   1.2e+02      71     113 ..     326     356 ..     295     410 .. 0.63

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 4.8e-05
  Methyltransf_32  21 akesgaltvvDvGaGkgYLsfvlalkekeyklkvvgidakeelvekaekraeklgkkfnkrlsfaelsie 90 
                      ++  g++ v++vGaG g  +f l  ++++ +lkv++ d +++ v+  ++ ++  + kf  r + ++ +++
       EEA22033.1 130 KQGAGPKVVLEVGAGAGNTAFPLINNNENEELKVFACDYSKNAVKVMRESEHYNE-KF-MRAEVWDVTSD 197
                      45688999****************966668************9999888776666.44.34444444443 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.085
  Methyltransf_32  71 aeklgkkfnkrlsfaelsieeatssktltkkveaeeekeeqee 113
                      ++k +++  +++s+++          t+++++++++e++eq+e
       EEA22033.1 326 ENKEEQQ--TETSTEK----------TTEESIDKNQEEQEQTE 356
                      3332222..2222222..........22333333333333332 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   1.3e-05     0.018      33      95 ..     136     200 ..     123     229 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 1.3e-05
                 SEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTT CS
         MTS  33 gkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleanklevevvasdvleevee 95 
                 + vl +G+GaG  +  l +++++ e  v ++d +++A+++ +e  + n+  +++   dv+++ ee
  EEA22033.1 136 KVVLEVGAGAGNTAFPLINNNENEElkVFACDYSKNAVKVMRESEHYNEKFMRAEVWDVTSDEEE 200
                 4599*********999987766555338899************9999998788888888877664 PP

>> DUF3408  Protein of unknown function (DUF3408)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.1       8.8   1.2e+04      65      76 ..     177     188 ..     167     190 .. 0.72
   2 ?   11.9   6.0   0.00013      0.18       3      68 ..     290     360 ..     289     385 .. 0.67

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 8.8
     DUF3408  65 tsledYeetFLk 76 
                 +++e Y+e+F++
  EEA22033.1 177 RESEHYNEKFMR 188
                 567889999876 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 0.00013
     DUF3408   3 dEellkeli.....vkkiplksk...peeeetpakeekeeakeeeeeeaeeeeekekkekkkrisekkrktsle 68 
                 dEe+l+++      +k++p+ ++   +e++++p+  e++e++++e ++++++ee+ +k+++   ++++ +++++
  EEA22033.1 290 DEEELRQMWstwtpEKGLPMVNNdisTENTDSPELAENKEEQQTETSTEKTTEESIDKNQE---EQEQTEDTEG 360
                 9********8888888899998886666666666655555555555555555555555444...4444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (422 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2103  (0.117296); expected 358.6 (0.02)
Passed bias filter:                      943  (0.0525964); expected 358.6 (0.02)
Passed Vit filter:                       101  (0.00563333); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.71u 0.34s 00:00:01.05 Elapsed: 00:00:00.47
# Mc/sec: 2703.31
//
Query:       EEA22034.1  [L=584]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.5e-17   62.8   0.8    4.5e-17   62.0   0.8    1.5  1  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.0   0.8   2.5e-21   4.5e-17       2     188 ..      54     235 ..      53     331 .. 0.87

  Alignments for each domain:
  == domain 1  score: 62.0 bits;  conditional E-value: 2.5e-21
  Fungal_trans   2 drffsnfh.pqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeili.hedfsspssslwilqs 96 
                   +++f +++ + f +++++ f++ +        +  +  l laila+  ++s+++  ++ +++  ++    + +l+++i++ +  + +  +++ i+q+
    EEA22034.1  54 KIYFLHCYnQPFSFFDEDRFMSRF------HWDGVPMYLQLAILATSIRYSSKACWRDCKEEAIDK----YACLSWDIISaSGLALVDEPDISIVQA 140
                   79******999******9999999......6667889999***********************988....6799******74455566677****** PP

  Fungal_trans  97 Llllelyektssd.ralher.........hhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinl 183
                     ll++      + +++h            +g+a+r++++l L r+   +        +e e+e+rrRl+w+ + l+++i+   Grp  + ds+ ++
    EEA22034.1 141 IALLSIIDTLDATkIKKHITagrkraswvKVGMAIRISQDLDLMRDTGLNI-------PESEQEERRRLFWSLYLLERIICCSSGRPLAIIDSDCHV 230
                   *****999998855666666666777766******************9975.......7777**************************778999999 PP

  Fungal_trans 184 pLPcd 188
                   +LP +
    EEA22034.1 231 RLPSE 235
                   99965 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (584 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       407  (0.0227007); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.41
# Mc/sec: 4232.03
//
Query:       EEA22035.1  [L=293]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.034   14.8   4.5       0.86   10.3   0.2    3.0  3  WBP-1     WW domain-binding protein 1


Domain annotation for each model (and alignments):
>> WBP-1  WW domain-binding protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.2   4.8e-05      0.86      61     104 .]      22      65 ..       5      65 .. 0.82
   2 ?    5.6   0.0    0.0014        25      72     104 .]     131     163 ..      80     163 .. 0.68
   3 ?   -3.0   0.1      0.63   1.1e+04      19      37 ..     257     279 ..     249     286 .. 0.65

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 4.8e-05
       WBP-1  61 vayreaknsaslvldlrllaslklPsyeevlkaarpetPpPpYs 104
                   + + ++  ++++++++  + +lP y++v +   p  P+P Y+
  EEA22035.1  22 YPDAGFMHRPETQMQMHMHMQHQLPRYDSVDHGYAPVVPLPRYT 65 
                 4446677778889999**************99999******995 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0014
       WBP-1  72 lvldlrllaslklPsy.eevlkaarpetPpPpYs 104
                 +++  +  +++  Ps   +  ++++ +tPpPpYs
  EEA22035.1 131 TTIMDDASSAYSFPSSfGHT-STETRDTPPPPYS 163
                 34555666677777765776.667788******7 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 0.63
       WBP-1  19 yElw....wfwlvwtllillsCi 37 
                  ++w    + +l+++++++++++
  EEA22035.1 257 QDTWhsspISFLIFVFIYFVQGV 279
                 55666666556677777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (293 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       630  (0.0351386); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.49
# Mc/sec: 1805.47
//
Query:       EEA22036.1  [L=519]
Description: heme a biosynthesis protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      4e-55  186.9  22.3    5.7e-55  186.3  22.3    1.3  1  UbiA      UbiA prenyltransferase family
  ------ inclusion threshold ------
       0.13   11.8   0.2       0.19   11.2   0.2    1.3  1  FTZ       Fushi tarazu (FTZ), N-terminal region


Domain annotation for each model (and alignments):
>> UbiA  UbiA prenyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  186.3  22.3   6.4e-59   5.7e-55      10     251 ..     199     454 ..     162     455 .. 0.88

  Alignments for each domain:
  == domain 1  score: 186.3 bits;  conditional E-value: 6.4e-59
        UbiA  10 alaaggspdlllllllllgtllaaaaanalNdyfDreiDadmertpnRPlvsGrispkealifaivllilgllllalllnpltallgllallly.vvYt 107
                 a   + s+++l++l l++gt+l +a+ana+N++f+ + Da+m+rt+nRPlv+G++s++ alifai++ ++g++ll++++np++a+l++++++ly ++Yt
  EEA22036.1 199 AQLPTLSTSTLTFLYLTAGTFLSSASANAFNMFFEPKYDALMSRTRNRPLVRGLVSTRGALIFAIATSLVGVGLLYIGTNPTVAGLSAANVVLYgFIYT 297
                 33444455669**************************************************************************************** PP

        UbiA 108 glrlKrrtllgtvvggiafglppllgwaavtgsl................sllalllalavflltwaialandlrdregDrkagiktlpvvlGrkaari 190
                   ++Kr+++++t++g+i++++pp++gw+a++g++                s+  ++la ++f+++++++   ++  r ++++ag +++  v  +++ar+
  EEA22036.1 298 --PMKRVHVINTWIGAIVGAIPPMMGWVAAAGQTattghdtwkdmlfseeSIGGWILASMLFAWQFPHFNSLSHLIRFEYKAAGHQMMCWVNPARNARV 394
                 ..***************************999999***************888888888877777777777777788899********99999999888 PP

        UbiA 191 l.lalllavlllallllllalllllylllalllaalallraarlvrrrdakkaakfflflss 251
                    +++l++++++   +++a++   ++l+++ la+ ++l++a+++++++++k++++ lf++s
  EEA22036.1 395 AlRYSVLMFPIAF--GFWWAGYVNNWFLVSSSLANGWMLKEAYRFWKYQGSKGSARGLFWAS 454
                 8766677777776..5666666666677777777888888899999999999999999*998 PP

>> FTZ  Fushi tarazu (FTZ), N-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.2   2.2e-05      0.19     192     257 ..      51     116 ..      19     161 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 2.2e-05
                 XXXXXXXXXXXXXXXXXXXXX.XXXXXXXXX.....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
         FTZ 192 ptpsasedvdyldvyspkkqa.knGdfatpppaattpatptsllveGistppqspaeksseeinhri 257
                  tps  +  +++  y p k+  knG f++ pp +   ++++s     i tp  s    +++e+ hr 
  EEA22036.1  51 STPSLFQKKEFFIAYNPSKRVfKNGFFSSLPP-TRGHTASLSTDSSTINTPIASGRSEQTQELPHRR 116
                 5888899999999****88888***9998887.45556666667789*********999******95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (519 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       637  (0.035529); expected 358.6 (0.02)
Passed bias filter:                      403  (0.0224776); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.46
# Mc/sec: 3364.22
//
Query:       EEA22037.1  [L=300]
Description: monosaccharide-P-dolichol utilization protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.9e-21   74.0   4.5    1.2e-10   41.0   0.8    2.5  2  PQ-loop   PQ loop repeat


Domain annotation for each model (and alignments):
>> PQ-loop  PQ loop repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.0   0.8   6.7e-15   1.2e-10       1      60 [.      60     119 ..      60     120 .. 0.97
   2 !   34.2   0.1   8.5e-13   1.5e-08       4      58 ..     176     230 ..     173     233 .. 0.91

  Alignments for each domain:
  == domain 1  score: 41.0 bits;  conditional E-value: 6.7e-15
     PQ-loop   1 lseilgyislvlwlvsyiPQiikNykrkSteGlSilflllwllGdilsllylilngfpps 60 
                 +s++lg++++  ++++++PQi+k  +++S  G+S+ ++ +++++ ++ l y++ ++fp+s
  EEA22037.1  60 ISKALGLAIVGASAIVKVPQILKLVNSRSSAGVSFMSYAMETASLLITLSYNVRQQFPFS 119
                 799******************************************************986 PP

  == domain 2  score: 34.2 bits;  conditional E-value: 8.5e-13
     PQ-loop   4 ilgyislvlwlvsyiPQiikNykrkSteGlSilflllwllGdilsllylilngfp 58 
                 +l+  + vl ++s++PQi ++y+   t++lS + ++  llG + ++++++ + ++
  EEA22037.1 176 LLQAGAGVLGVASKLPQIFTIYQEGTTGQLSAFAVFNYLLGTLSRIFTTLQEVDD 230
                 5677788999***************************************998766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (300 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       697  (0.0388756); expected 358.6 (0.02)
Passed bias filter:                      356  (0.0198561); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.49
# Mc/sec: 1826.23
//
Query:       EEA22038.1  [L=254]
Description: RNA polymerase II mediator complex component Med8, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.9e-65  220.7   0.0    2.4e-65  220.4   0.0    1.0  1  Med8             Mediator of RNA polymerase II transcription 
  ------ inclusion threshold ------
      0.088   12.6   1.5       0.11   12.2   0.7    1.5  2  Pox_Ag35         Pox virus Ag35 surface protein
       0.14   12.5   8.2       0.31   11.5   8.2    1.5  1  CENP-B_dimeris   Centromere protein B dimerisation domain
       0.23   10.6   5.9       0.29   10.3   5.9    1.2  1  DUF2457          Protein of unknown function (DUF2457)
        2.1    8.5  10.7          3    8.0  10.7    1.2  1  RNA_pol_3_Rpc31  DNA-directed RNA polymerase III subunit Rpc3
        4.7    6.4   9.8        6.3    6.0   9.8    1.1  1  NOA36            NOA36 protein
          8    4.4   9.0         14    3.6   9.0    1.3  1  DNA_pol_phi      DNA polymerase phi
        8.7    6.2   9.6         17    5.2   9.6    1.4  1  Sigma70_ner      Sigma-70, non-essential region


Domain annotation for each model (and alignments):
>> Med8  Mediator of RNA polymerase II transcription complex subunit 8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  220.4   0.0     1e-68   2.4e-65       1     228 [.       1     249 [.       1     251 [. 0.89

  Alignments for each domain:
  == domain 1  score: 220.4 bits;  conditional E-value: 1e-68
        Med8   1 mq.reekqLeasLealrqRladLksslaslinkleqedellsWpslldqaallSnnLttlsklLksektplLrnlvvlPlllsperdeeLakltegRvp 98 
                 m+ ++e q+++ Le++rqRl +L++sl+sl+ +l+++d+l+sW+sl++qa+++SnnL +++++L +e+++lL++lv++P +++p+++++          
  EEA22038.1   1 MTaINESQVKI-LEQTRQRLLQLTHSLDSLTGSLHHSDPLPSWSSLQSQASIISNNLVNICSQL-AEHQELLSSLVAYPAPSFPGNTQQ---------- 87 
                 66699******.****************************************************.************************.......... PP

        Med8  99 vfsHevvpdlLRtKldPevE................................ekeaqleakarnlggeatlekqeaglnkvvtgllrkl....ekaree 161
                      v+++lLRtKldP+vE                                + ea+ ea++rn+gg++t+e++e+g+++vvtgl+r+l    +++ e+
  EEA22038.1  88 ----GVLEQLLRTKLDPRVEdwvtrgriagteassgdaglsesdlaelwswaPIEANAEARRRNWGGNYTHEEKEMGIQNVVTGLKRTLpdddDDEDED 182
                 ....*************************************************************************************8754333333 PP

        Med8 162 weeeeeeraeekqtssladtealvaavalgkglkagvevdiaapp......sass..gvmgKlpsviktnikgas 228
                 ++e+e+e+ e+  +  ++++++  ++v++++g+ +gve+dia ++         +  +++  l++v++++++ga+
  EEA22038.1 183 EDEDEDEEFED-VDEGGEKMDI--VGVHTRPGA-SGVEFDIARSRdhvlsaA--AspAIP--LDEVFRYMMTGAK 249
                 34444444333.3345666776..*********.799****98887666433..145888..***********96 PP

>> Pox_Ag35  Pox virus Ag35 surface protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       2.7     6e+03      13      34 ..       7      28 ..       3      41 .. 0.72
   2 ?   12.2   0.7     5e-05      0.11      56     110 ..     140     197 ..     117     209 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 2.7
    Pox_Ag35 13 dsfktleeiRahlrseaedadk 34
                +++k le+ R++l   + + d 
  EEA22038.1  7 SQVKILEQTRQRLLQLTHSLDS 28
                4588888888888777766665 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 5e-05
    Pox_Ag35  56 rattprkk...pakkekkkkeeekeeaaeeeeledseedeenendedeseesvqaeee 110
                 +a+++r++     ++e+k+   ++  +  ++ l+d+++de++++dede ee  +++e+
  EEA22038.1 140 NAEARRRNwggNYTHEEKEMGIQNVVTGLKRTLPDDDDDEDEDEDEDEDEEFEDVDEG 197
                 5566666555444444444444555555566899999999999999999998888876 PP

>> CENP-B_dimeris  Centromere protein B dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   8.2   0.00014      0.31      23      53 ..     174     204 ..     169     228 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00014
  CENP-B_dimeris  23 eeedeededeeddedddevpvpsfgeamayf 53 
                     +++d+edede++ded++   v   ge m  +
      EEA22038.1 174 DDDDDEDEDEDEDEDEEFEDVDEGGEKMDIV 204
                     5677777777777777777777777777655 PP

>> DUF2457  Protein of unknown function (DUF2457)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   5.9   0.00013      0.29      58      87 ..     174     196 ..      99     217 .. 0.56

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00013
     DUF2457  58 eddeedeeddddddddedddedddeedede 87 
                 +dd++++ed+d+d+d+e        ed de
  EEA22038.1 174 DDDDDEDEDEDEDEDEEF-------EDVDE 196
                 222222222222222222.......22222 PP

>> RNA_pol_3_Rpc31  DNA-directed RNA polymerase III subunit Rpc31
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0  10.7    0.0014         3     155     210 ..     144     196 ..     123     202 .. 0.56

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0014
  RNA_pol_3_Rpc31 155 kkkk.....eadeedeegkelleklkelaeeeddeeekkekedeeeeeeeeeddefdddde 210
                      +++       ++e++   +++   lk++  ++dd        de+e+e+e+ed+ef+d de
       EEA22038.1 144 RRRNwggnyTHEEKEMGIQNVVTGLKRTLPDDDD--------DEDEDEDEDEDEEFEDVDE 196
                      3333566655556666667777777754444444........2333334678999998886 PP

>> NOA36  NOA36 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   9.8    0.0028       6.3     275     297 ..     174     196 ..     138     204 .. 0.50

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.0028
       NOA36 275 edddddddeedddeeeddedeee 297
                 +dddd+d++ed+de+e+ ed +e
  EEA22038.1 174 DDDDDEDEDEDEDEDEEFEDVDE 196
                 22222333333333333333332 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   9.0    0.0062        14     647     684 ..     174     195 ..     153     211 .. 0.48

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.0062
  DNA_pol_phi 647 ddeeeeeeddeededseedddeeesdedeededdedvd 684
                  dd+++e+ed++eded+e                 edvd
   EEA22038.1 174 DDDDDEDEDEDEDEDEE----------------FEDVD 195
                  22222222222222222................22222 PP

>> Sigma70_ner  Sigma-70, non-essential region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   9.6    0.0078        17      16      56 ..     155     196 ..     152     207 .. 0.60

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.0078
  Sigma70_ner  16 eageirLrdiidGflDeeeeeeeeeeeedeeeeeee.eddde 56 
                  e+ e+ ++++++G+     +++++e+e+++e+e+ee ed de
   EEA22038.1 155 EEKEMGIQNVVTGLKRTLPDDDDDEDEDEDEDEDEEfEDVDE 196
                  7889*********99944444444444444444444433332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (254 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       867  (0.0483574); expected 358.6 (0.02)
Passed bias filter:                      664  (0.037035); expected 358.6 (0.02)
Passed Vit filter:                       108  (0.00602376); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.50u 0.29s 00:00:00.79 Elapsed: 00:00:00.42
# Mc/sec: 1800.47
//
Query:       EEA22039.1  [L=305]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.5e-06   26.5   0.1     0.0092   15.6   0.1    2.1  2  Abhydrolase_1  alpha/beta hydrolase fold
    2.7e-05   24.9   0.0    3.9e-05   24.4   0.0    1.2  1  Abhydrolase_6  Alpha/beta hydrolase family
     0.0026   17.4   0.1     0.0056   16.3   0.0    1.6  2  Peptidase_S15  X-Pro dipeptidyl-peptidase (S15 family)
     0.0041   16.6   0.4        1.7    8.1   0.1    2.3  2  Peptidase_S9   Prolyl oligopeptidase family
      0.005   16.1   0.0       0.05   12.9   0.0    2.0  2  Hydrolase_4    Serine aminopeptidase, S33
  ------ inclusion threshold ------
      0.081   12.0   0.0       0.11   11.6   0.0    1.1  1  Roughex        Drosophila roughex protein
       0.13   11.6   0.0       0.22   10.9   0.0    1.3  1  DUF1776        Fungal family of unknown function (DUF1776)


Domain annotation for each model (and alignments):
>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.1   3.6e-06    0.0092      20      88 ..      59     132 ..      47     134 .. 0.80
   2 !    9.0   0.0   0.00038      0.98     213     251 ..     241     284 ..     160     288 .. 0.82

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 3.6e-06
                    HHHHHHHHTTSEEEEEEETTSTTSSSTTTGB.....CHHSHHHHHHHHH..HHHHHCTTSSEEEEEETHHHHHHH CS
  Abhydrolase_1  20 glapaLakdgfdvillDlrGvgySspapacin....ddygtasvaddld..rildalgddkltlvGhSmGGmial 88 
                    ++   L ++g+ v++l+ rG  yS  + ++       dy  a +  +l+  ++l++ +  +l+l G+S+G+mia+
     EEA22039.1  59 SITTELVRKGYIVLTLNFRGASYSGGSTSWTGkpemGDYISA-YGFILKysQLLAPGKHVELVLAGYSYGSMIAS 132
                    556677888***************999999779889666553.4556667788********************97 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00038
                    EEEEEEETTCSSSCHHHHHHHHHCHTS.....EEEEEEETCSSS CS
  Abhydrolase_1 213 ptlvisgtsDplvppkaledlaqllpk.....krlvvisdagHl 251
                     +l+++gt+D+ +++k l +++++l++     + +v +  agH+
     EEA22039.1 241 RSLIVYGTDDMFTSEKKLQNWTKKLKDapesqVDVVEVRMAGHF 284
                    79**********************77766678888999999997 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4   0.0   1.5e-08   3.9e-05      20     211 ..      62     287 ..      40     294 .. 0.51

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 1.5e-08
                    HHHHCCTCEEEEE--TTS...TS-GGCS--HHHCHHHHHHHCCTT........TTSE..EEEEETCHHHHHHHHHHCC.....EEEEES-..---- CS
  Abhydrolase_6  20 aallaagvhvlapDlpGh...Grsdpppldledladlaalldelaa......gggpv..vlvGHSlGGalalaaapla...lvvgvlldppptalp 101
                     +l ++g+ vl++ ++G    G+ ++++++ ++  d+  +   + +       g+ v  vl G+S+G ++a++   ++   +v++++  p   +++
     EEA22039.1  62 TELVRKGYIVLTLNFRGAsysGG-STSWTGKPEMGDYISAYGFILKysqllaPGKHVelVLAGYSYGSMIASH---QPnvdDVISIFSKP---TGD 150
                    56667777778888888877742.33333333334443322222223334433355566**************...77764667788888...444 PP

                    TTTS----TTHHHHHHTT-C..CCCH.CCH..S-HSCCCCHHHCCCCHCHCCCGHHHHCCHHCHTTCCHHTT-TTGC.................EE CS
  Abhydrolase_6 102 agllaaalelllallallrl..lawl.sre..plprlfladedadaawrarlarlaallaglgllpaaawadlpvpl.................lv 175
                     + ++ +++  +  ++++     ++  ++e  +++++  + ++  a     l  +  + a  +   + +++ l v+                  l+
     EEA22039.1 151 SLAARILAKAKKLITSAEEEteEEFYgTEEvqLDDDTASDLPP--AKISFLLVSPILSYALGFVTLWGNLTKLSVQGhnivtpaleerlpkfrsLI 244
                    4443333333332222222222333323324422223333333..222222222222222222223444444444445555555555555556666 PP

                    ECTT-C......HHHHCHHCCCH..STTEEETCE...SSS-HHH CS
  Abhydrolase_6 176 lggeDp......lvprllerlla..qagarlpvvlpgaGHlphl 211
                    ++g+D+       ++ + ++l       +++ v+++ aGH++ +
     EEA22039.1 245 VYGTDDmftsekKLQNWTKKLKDapESQVDV-VEVRMAGHFWVE 287
                    6655554866554445544444455566666.********8765 PP

>> Peptidase_S15  X-Pro dipeptidyl-peptidase (S15 family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   2.2e-06    0.0056       1      88 [.      14      99 ..      14     134 .. 0.74
   2 ?   -2.3   0.0         1   2.6e+03     232     259 ..     243     283 ..     227     293 .. 0.52

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 2.2e-06
                   TS-EEEEEEEEE..TTSSSEEEE...EEEESS-CCT.CCCCHTTCHHCCHGGGHHHHHTT-EEEEEE-TTSTTS-S---TTTTTHHHHHHH CS
  Peptidase_S15  1 DGvrLavdiyrPetkskeklPvl...ltrtPYgkndelasdkalaleelelqdkvfvarGYavVvqdvrGtggSeGeftvgdsdeaedgad 88
                   DG+rL+ +iy  +  + ++lP+l     + PY       s++    ++ +   +++v++GY+v+  + rG  +S G + ++++ e  d+ +
     EEA22039.1 14 DGTRLSCRIYQLDGINYQELPALkaaIVAHPYASL--GGSNDDPVVASIT---TELVRKGYIVLTLNFRGASYSGGSTSWTGKPEMGDYIS 99
                   88899999998866677888887444667888832..2333333333332...349************************99999988776 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1
                    EEEEECCSSTTC.CHHHHHHH.HHCCTT-............E CS
  Peptidase_S15 232 llvgGwnDwnvk.ngaiklye.alkapgv............k 259
                    l+v G  D +++ ++ ++++  +lk++++            +
     EEA22039.1 243 LIVYGTDD-MFTsEKKLQNWTkKLKDAPEsqvdvvevrmagH 283
                    55566666.555555555553134444334444444444444 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.1   0.1   0.00065       1.7       9      76 ..      64     129 ..      56     134 .. 0.69
   2 !    6.6   0.0    0.0019       4.9     145     207 ..     241     304 ..     222     305 .] 0.88

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00065
                   HHHCCT-EEEEE--TTSSTTHCHHHHTTSGGGGHH.HHHHHHHHHHHHHHTT.S--GGGEEEEEETHHHH CS
  Peptidase_S9   9 lladrGyvvvvanirGsggyGeafhdagkrklgqn.efdDfiaaaealakeg.yvdserlaitGgSyGGy 76 
                   l+  +Gy+v+  n+rG ++ G +    gk ++g++ ++  fi     l + g  v   +l++ G SyG +
    EEA22039.1  64 LV-RKGYIVLTLNFRGASYSGGSTSWTGKPEMGDYiSAYGFILKYSQLLAPGkHV---ELVLAGYSYGSM 129
                   44.89***************99999888888887523344444444444444333...677777777765 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0019
                   EEEEEEETT-SSS-THHHHHHHHHHH--S-S.EEEEEETTS-SSTTSSHHHHHHHHHHHHHHHH CS
  Peptidase_S9 145 plLlihGlaDdrvppaealklvaaLqkkgkn.vlllifpdegHgvgkprakveelarllaFlke 207
                   + L++ G+ D  +  ++   + ++L+++ +  v+++    +gH   +p+ +++  + +  +l++
    EEA22039.1 241 RSLIVYGTDDMFTSEKKLQNWTKKLKDAPESqVDVVEVRMAGHFWVEPSFHQKLRQAISGWLEQ 304
                   67999999999999999*********666666***********9999**************987 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.9   0.0     2e-05      0.05      21      91 ..      58     132 ..      53     136 .. 0.80
   2 ?    0.8   0.0     0.098   2.5e+02     192     219 ..     240     267 ..     217     279 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2e-05
  Hydrolase_4  21 aelaeaLaaqGfavyalDhrGhGrsegkrghv..psfddyvdDlaafvekvk..eehpelplfllGhSmGGlial 91 
                  a ++ +L+++G+ v++l+ rG   s+g + +   p++ dy+     +++  +  ++ ++ +l+l G S G++ia 
   EEA22039.1  58 ASITTELVRKGYIVLTLNFRGASYSGGSTSWTgkPEMGDYISAYGFILKYSQllAPGKHVELVLAGYSYGSMIAS 132
                  567899*******************98877543377888998887777666621555555*************96 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.098
  Hydrolase_4 192 lPllllhGeaDkvvdpeasrelyerlgs 219
                  +  l+++G++D  +++++ ++  ++l+ 
   EEA22039.1 240 FRSLIVYGTDDMFTSEKKLQNWTKKLKD 267
                  3489***********9999888887764 PP

>> Roughex  Drosophila roughex protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   4.3e-05      0.11     190     276 ..     101     193 ..      66     196 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 4.3e-05
     Roughex 190 yllklkrstlvppptveelfsisrlrraslaranpqtdd........eeeevpqarslsvrrilfadgadedgdedtdgsveekkddasepdlpd 276
                 y   lk s l+ p    el+  ++   + +a  +p+ dd         +++   ar l+  + l++ +a+e+ +e+  g+ e + dd +  dlp 
  EEA22039.1 101 YGFILKYSQLLAPGKHVELVLAGYSYGSMIASHQPNVDDvisifskpTGDS-LAARILAKAKKLIT-SAEEETEEEFYGTEEVQLDDDTASDLPP 193
                 5667999******9999**********************997766533443.34566666677888.899*******9**************995 PP

>> DUF1776  Fungal family of unknown function (DUF1776)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   8.4e-05      0.22      10      32 ..      50      72 ..      47      79 .. 0.92

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 8.4e-05
     DUF1776 10 GsptePltRsialDLerrGFiVf 32
                Gs  +P++ si ++L r+G+iV 
  EEA22039.1 50 GSNDDPVVASITTELVRKGYIVL 72
                999******************95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (305 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       493  (0.0274974); expected 358.6 (0.02)
Passed bias filter:                      468  (0.026103); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.45
# Mc/sec: 2019.24
//
Query:       EEA22040.1  [L=759]
Description: Patatin family phospholipase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.1e-35  119.7   0.8    1.3e-34  118.8   0.8    1.4  1  DUF3336   Domain of unknown function (DUF3336)
    1.1e-18   68.2   0.0    2.5e-18   67.0   0.0    1.6  1  Patatin   Patatin-like phospholipase


Domain annotation for each model (and alignments):
>> DUF3336  Domain of unknown function (DUF3336)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.8   0.8   1.5e-38   1.3e-34       5     120 ..      81     197 ..      77     216 .. 0.94

  Alignments for each domain:
  == domain 1  score: 118.8 bits;  conditional E-value: 1.5e-38
     DUF3336   5 rgkrkklrkklrkattYeeWkeaAkeLDellgndeWkendes.yYdyklvkkvlkkLrklrekedlkellellrtclkrNfagienprLYsetyiGTKk 102
                 +++++ l  k+r+a ++eeW+++A eLDel+gn++Wke+ es +Y+  lv +++k+L+++r ++d++++l+l+rt l+r++++++++ LY++++iGTK+
  EEA22040.1  81 DNRKQLLYLKMRNAVSFEEWRSCACELDELEGNNQWKETFESdEYNPVLVLERMKELEDARISCDVSRMLFLVRTALTRDLGNMSSAALYRHSHIGTKN 179
                 578999********************************************************************************************* PP

     DUF3336 103 lieeYidevekalellae 120
                 li++Yi+++ +++++l++
  EEA22040.1 180 LINQYITTALNTISTLLD 197
                 *************99976 PP

>> Patatin  Patatin-like phospholipase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.0   0.0   2.8e-22   2.5e-18       2     195 ..     229     416 ..     228     424 .. 0.84

  Alignments for each domain:
  == domain 1  score: 67.0 bits;  conditional E-value: 2.8e-22
     Patatin   2 vlsGGGsrgafslgalkaLkkelgerfdiisGtSaGAiialllalgrdpa..alvddlrnlllnkifdrdllirelaanlaarlsgllgkgglfdaeal 98 
                 +lsGGG+ g  ++g++kaL +e+   ++iisG+SaG+i+a+++++ +d++  a  +++   +l+ ++  +         + +   +ll  g+ +d  +l
  EEA22040.1 229 SLSGGGTFGMNHVGVIKAL-WEAKLVPRIISGASAGSIVASIFCAHTDDQipAVLEAFPYGELDVFEPEG-----NQLPPLQKMARLLKYGSVYDSSNL 321
                 79*****************.********************999999766511445666666666666666.....66778889999************* PP

     Patatin  99 rellrkvladktlkrlsarlgklpllkslftanqavpaittataatastanranglytedddddvdladavraSsafPglfppvsl......dge.... 187
                 ++ +r +l+d+t++++  r +k+                  +   + +  +    l+++ ++++v +++a+  S+++P++f+p  l      +ge    
  EEA22040.1 322 ERVMRNWLGDMTFHEAYNRTRKI-----------------LNICISSAGLYELPRLLNYITAPNVLIWSAITVSCSVPFVFSPSVLmakdplTGEnvaw 403
                 ***********************.................7999*************************************666555555553335555 PP

     Patatin 188 .....lyvDGGil 195
                      +++DG++ 
  EEA22040.1 404 hdepgQWIDGSVD 416
                 5556799999985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (759 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       441  (0.024597); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.27s 00:00:00.90 Elapsed: 00:00:00.43
# Mc/sec: 5250.12
//
Query:       EEA22041.1  [L=752]
Description: alpha/beta hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.9e-13   49.3   0.0    2.5e-12   47.9   0.0    1.8  2  Abhydrolase_6  Alpha/beta hydrolase family
    1.3e-11   44.6   0.0    2.9e-11   43.5   0.0    1.6  1  Abhydrolase_1  alpha/beta hydrolase fold
      3e-07   30.0   0.0      6e-07   29.0   0.0    1.5  1  Hydrolase_4    Serine aminopeptidase, S33
    3.5e-05   22.7   0.0     0.0003   19.6   0.0    2.0  1  Ndr            Ndr family
    6.9e-05   22.6   0.0    0.00012   21.8   0.0    1.4  1  Esterase       Putative esterase
    0.00067   20.7   0.1       0.48   11.6   0.0    2.9  2  EthD           EthD domain
  ------ inclusion threshold ------
      0.014   16.0   0.0      0.028   15.1   0.0    1.4  1  zf-RVT         zinc-binding in reverse transcriptase
       0.13   12.0   0.0       0.27   11.0   0.0    1.4  1  Abhydrolase_2  Phospholipase/Carboxylesterase


Domain annotation for each model (and alignments):
>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   0.0         8   1.8e+04     122     137 ..     231     247 ..     196     273 .. 0.55
   2 !   47.9   0.0   1.1e-15   2.5e-12       2     219 ..     306     556 ..     305     557 .. 0.53

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 8
                    CCCHCCH.S-HSCCCCH CS
  Abhydrolase_6 122 lawlsre.plprlflad 137
                    ++w  +  p+pr++ + 
     EEA22041.1 231 YEWYYTFgPAPRDLTSL 247
                    33332222222222222 PP

  == domain 2  score: 47.9 bits;  conditional E-value: 1.1e-15
                    EEE--GC.....G..C.HHHHHHHHCCTCEEEEE--TTSTS-GGCS--HHH..C.HHHHHHHCCTT..TTSEEEEEETCHHHHHHH.HHHCC..EE CS
  Abhydrolase_6   2 lllHGagssassW..l.vapLaallaagvhvlapDlpGhGrsdpppldled..l.adlaalldelaagggpvvlvGHSlGGalala.aaplalvvg 90 
                    +l++   s+ ++W  +  +++ +  ++ ++v+ +  +G   sdp  + ++   l +d+  +l++l+ ++ ++ ++G SlGGa al  a++++ +v+
     EEA22041.1 306 VLVNSILSDWGIWdeFlDVFFSNPKNQKYRVVRYRPRGRA-SDPGETPVTMdlLsQDVITILNALR-VPQAAAVIGVSLGGATALNtALKYPTRVA 399
                    6666555555566432233444444444999********5.3333333333333488899999998.66666**************5555664444 PP

                    ..EEES-......----TTT..S----TTHHHHHH.TT-CCCCHCCH........S-HSCCCCHHH....C....CCCHCHCCCGHHHHCCHHC.H CS
  Abhydrolase_6  91 ..vlldp....pptalpagl..laaalelllalla.llrllawlsre........plprlfladed....a....daawrarlarlaallaglg.l 160
                      v+ d+    p ++ p+++  + a++e    +++ + + ++++ ++         + ++ +++ +    a    ++ ++  l +  ++ ++l+ +
     EEA22041.1 400 nfVACDTnslaP-PSNPTAWgeRIALAEAESEAPTdPKTGARLVGEKlaeittrrWFVPSSYDGGAqqarAekvkQYVVTNHLEGFKKSVNALYsY 494
                    455555544432.35555554422222222222222222222222222332111222224444333343322222333333333333444455523 PP

                    TTCCHHTT-TTGCEEE.CTT-CHHH....HCHHCCCHSTTEEETCE...SSS-HHHHSHHHHHH CS
  Abhydrolase_6 161 lpaaawadlpvpllvl.ggeDplvp....rllerllaqagarlpvvlpgaGHlphleepdevae 219
                      +++ ++  v+ l + g++D ++p     ++e++++ +g +l ++++gaGHlp+ e+p+e+a+
     EEA22041.1 495 DLREEMKTGSVRGLFVvGSGDGVLPqgmkKMAEDYGV-EGTEL-KIVEGAGHLPMAEQPEEFAK 556
                    3466777777777544499999777333355666666.99999.******************97 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.5   0.0   1.3e-14   2.9e-11       1     252 [.     303     546 ..     303     551 .. 0.71

  Alignments for each domain:
  == domain 1  score: 43.5 bits;  conditional E-value: 1.3e-14
                    SEEEEE-STTTCGGGGTTGHHHHHHHHT....TSEEEEEEETTSTTSSSTTTGB.CHHSHHHHHHHHHHHHHHCTTSSEE.EEEETHHHHHHHHHH CS
  Abhydrolase_1   1 pvlvilhGlpgssdvwaerglapaLakd....gfdvillDlrGvgySspapacinddygtasvaddldrildalgddklt.lvGhSmGGmialaya 91 
                    p++v++  ++  +++w e  + + +  +    +++v+ + +rG ++ +       +++ +  +  d+  il+al + + + ++G S+GG++al+ a
     EEA22041.1 303 PLIVLVNSILSDWGIWDE--FLDVFFSNpknqKYRVVRYRPRGRASDPGETP---VTMDL--LSQDVITILNALRVPQAAaVIGVSLGGATALNTA 391
                    567888888888888888..4444444446689**********998866666...55555..9********************************* PP

                    HHHGGGEEEEEEESECSSCCHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHHHHCCSCHHHHHHHHHHHHHHHCHHHCCHHHHHHHCHHHHHHHHH CS
  Abhydrolase_1  92 aeyperVkalvllgaidpaaslieaqrqqaksfpdffdgyaadcarnpagplladelaaleqrhrlvdalkfpdkskrfpssgsdnasslatgalk 187
                    ++yp rV+++v++++  ++ ++ +    + ++   +     a+  ++++++l++ +la +++r  +v     p++++   ++ ++ ++ ++++  +
     EEA22041.1 392 LKYPTRVANFVACDT--NSLAPPSNPTAWGERIALAEAESEAPTDPKTGARLVGEKLAEITTRRWFV-----PSSYDGGAQQARA-EKVKQYVVTN 479
                    ***************..66666666666666666666666688888888888888888888888877.....5555555554433.3333333335 PP

                    HHHHHHHCCHHHHHHHHHCTHHHHS...EEEEEEETTCSSSCHHHHHHHHHC..HTSEEEEEEETCSSSH CS
  Abhydrolase_1 188 sieqwpttdsaklllrlrelknvla...ptlvisgtsDplvppkaledlaql..lpkkrlvvisdagHla 252
                    ++e+++   +a +  +lre  +++      l++ g+ D++ p + + ++a++    + +l+++++agHl 
     EEA22041.1 480 HLEGFKKSVNALYSYDLRE--EMKTgsvRGLFVVGSGDGVLP-QGMKKMAEDygVEGTELKIVEGAGHLP 546
                    5555555554444444444..333333388889999999998.445555555588889999999999976 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.0   0.0   2.7e-10     6e-07      30     238 ..     332     550 ..     321     551 .. 0.82

  Alignments for each domain:
  == domain 1  score: 29.0 bits;  conditional E-value: 2.7e-10
  Hydrolase_4  30 qGfavyalDhrGhGrsegkrghvpsfddyvdDlaafvekvkeehpelplfllGhSmGGliallyllrypdkvaglilsaPalkikakl.......... 117
                  q + v+ +  rG    +g++     +d + +D+ +++++++ ++      ++G S+GG++al+ +l+yp +va ++ + ++   +++           
   EEA22041.1 332 QKYRVVRYRPRGRASDPGETP--VTMDLLSQDVITILNALRVPQA---AAVIGVSLGGATALNTALKYPTRVANFVACDTNSLAPPSNptawgerial 424
                  667777777777777766665..5788889999999999996554...56****************************99987777777888888888 PP

  Hydrolase_4 118 ........k.appllklllkllgkllpklqv.snnlkadslsrdpevvaayeadplv.hgkitvrlllelldamkrleeraakitlPllllhGeaDkv 204
                            ++  ++l+ + l+++  +  + +++ +    +   e+v++y    ++ ++k +v+ l++      +l+e+ +  ++  l++ G+ D v
   EEA22041.1 425 aeaeseapTdPKTGARLVGEKLAEITTRRWFvPSSYDGGAQQARAEKVKQYVVTNHLeGFKKSVNALYSY-----DLREEMKTGSVRGLFVVGSGDGV 517
                  88887666335555666665555554443336999****************999999999****999975.....7888888888999********** PP

  Hydrolase_4 205 vdpeasrelyerlgskdktlklypglyHellnEp 238
                   + ++ ++++e  g +  +lk+ +g+ H  + E+
   EEA22041.1 518 LP-QGMKKMAEDYGVEGTELKIVEGAGHLPMAEQ 550
                  98.8889**********************99996 PP

>> Ndr  Ndr family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.0   1.3e-07    0.0003      79     276 ..     352     562 ..     345     564 .. 0.72

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 1.3e-07
                 ---HHHHHTTHHHHHHHHT---EEE.EEETHHHHHHHHHHHHSGGGEEEEEEES---S--.....-HHHHHHHHHH.............TTTS-HHHHH CS
         Ndr  79 fpslddladqllavldhfklksvig.lGvgaGAyilarfalkhperveglvLinitskaa.....gwvewakeKls.sk.....llkkvgltdllkdll 165
                   ++d l++++ ++l+ +++ ++ + +Gv  G    +  alk+p rv   v  +++s a+     +w e+++     s+     +     + + l ++ 
  EEA22041.1 352 PVTMDLLSQDVITILNALRVPQAAAvIGVSLGGATALNTALKYPTRVANFVACDTNSLAPpsnptAWGERIALAEAeSEaptdpKTGARLVGEKLAEIT 450
                 569*****************8765538999999999999*************99988775211114444433221101100000222233445555555 PP

                 HHHHS-HHHHHHT-HHHHHHHHHHHT-TTHHHHHHHHHHHHT..-------TTSSSS-EEEEEETTSTTH.HHHHHHHHHS-TTTEEEEEETT-TT-HH CS
         Ndr 166 lahkFgkeeksensdlvreyrkllkerlnsknlelyleaynk..RrdleierkklevkvllvvGdkspfv.devvevnskldkkkttllkvadsgglvl 261
                   + F   +        ++  +++k+ + ++ le + +++n     dl +e+k+ +v+ l vvG+    + + + +++++ + + t+l  v+ +g l++
  EEA22041.1 451 TRRWFVPSSYDG--GAQQARAEKVKQYVVTNHLEGFKKSVNAlySYDLREEMKTGSVRGLFVVGSGDGVLpQGMKKMAEDYGVEGTELKIVEGAGHLPM 547
                 555555544433..355556677888888889999999988633579999***99**********98877256778*********************** PP

                 HH-HHHHHHHHHHHH CS
         Ndr 262 eeqPdklaeslklfl 276
                 +eqP+  a+ +  fl
  EEA22041.1 548 AEQPEEFAKVIDAFL 562
                 *********999998 PP

>> Esterase  Putative esterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   0.0   5.3e-08   0.00012     114     159 ..     372     420 ..     328     489 .. 0.72

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 5.3e-08
                 CCCEEEEEETHHHHHHHHHHHCSTTTCCEEE...EES--S-CC.HCHHHC CS
    Esterase 114 pdgravaGqSmGGlgALilalkhpdrFgsvs...sfSpivnps.namWgq 159
                 p++ av+G S+GG +AL++alk+p+r ++       S ++ ps +  Wg+
  EEA22041.1 372 PQAAAVIGVSLGGATALNTALKYPTRVANFVacdTNS-LAPPSnPTAWGE 420
                 2337*********************975433011222.222333334555 PP

>> EthD  EthD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.6   0.0   0.00021      0.48       1      25 [.      14      38 ..      14      90 .. 0.79
   2 ?    6.1   0.0     0.011        24       4      33 ..     146     177 ..     143     209 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00021
                --S-HHHHHHHHHHTHHHHHCTSTT CS
        EthD  1 pglspeeFrdyweevHaplvkdllg 25
                pgl p++F+d+++++H+pl ++l+ 
  EEA22041.1 14 PGLPPSQFHDWYNNEHGPLRLRLPF 38
                899****************988875 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.011
                 -HHHHHHHHHHTHHHHHCTSTT.......... CS
        EthD   4 speeFrdyweevHaplvkdllg.g.irryvlr 33 
                 +++   ++++++H++l+++++g    rr+v  
  EEA22041.1 146 TESKVDRWYNDEHIELLQKVPGwRrSRRFVTS 177
                 6777899***************7335555533 PP

>> zf-RVT  zinc-binding in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.1   0.0   1.2e-05     0.028      50      80 ..     658     687 ..     644     691 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 1.2e-05
      zf-RVT  50 llkrgiesssrCqlCgqeeEtieHlfleCpf 80 
                 l++ g++ +s  + Cgq+ Et+eH +++C++
  EEA22041.1 658 LNRIGAA-DSDLCACGQASETVEHFLFRCTK 687
                 5555555.666679***************86 PP

>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00012      0.27      86     140 ..     354     408 ..     330     423 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00012
                    HHHHHHHHHHHHHHTT--GGGEEEEEETHHHHHHHHHHHT-SS--SEEEEES--- CS
  Abhydrolase_2  86 saekleelidaelkkgipssriiigGFSqGaalalylaltlpkklggivafsgal 140
                    ++  l++ +   l++ +  ++ +++G S G+a al +al++p++++  va+    
     EEA22041.1 354 TMDLLSQDVITILNALRVPQAAAVIGVSLGGATALNTALKYPTRVANFVACDTNS 408
                    55666666666667777788899**************************997654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (752 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       429  (0.0239277); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.67u 0.26s 00:00:00.93 Elapsed: 00:00:00.43
# Mc/sec: 5251.15
//
Query:       EEA22042.1  [L=439]
Description: hypothetical protein PMAA_058220 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (439 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       510  (0.0284455); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.42
# Mc/sec: 3166.88
//
Query:       EEA22043.1  [L=354]
Description: hypothetical protein PMAA_058230 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (354 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       298  (0.0166211); expected 358.6 (0.02)
Passed bias filter:                      225  (0.0125495); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2545.24
//
Query:       EEA22044.1  [L=315]
Description: hypothetical protein PMAA_058240 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (315 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       345  (0.0192426); expected 358.6 (0.02)
Passed bias filter:                      314  (0.0175135); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2341.27
//
Query:       EEA22045.1  [L=347]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (347 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       576  (0.0321267); expected 358.6 (0.02)
Passed bias filter:                      202  (0.0112667); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 2552.06
//
Query:       EEA22046.1  [L=556]
Description: alpha-amylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.1e-44  152.5   0.1    3.1e-44  151.9   0.1    1.2  1  Alpha-amylase  Alpha amylase, catalytic domain
    6.1e-24   84.1   0.0    1.2e-23   83.2   0.0    1.5  1  DUF1966        Domain of unknown function (DUF1966)
  ------ inclusion threshold ------
      0.019   14.9   0.0        1.4    8.9   0.0    2.4  2  UBA_6          UBA-like domain


Domain annotation for each model (and alignments):
>> Alpha-amylase  Alpha amylase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  151.9   0.1   5.1e-48   3.1e-44       1     334 [.      56     360 ..      56     363 .. 0.87

  Alignments for each domain:
  == domain 1  score: 151.9 bits;  conditional E-value: 5.1e-48
                    --CHHHHCTCCCCCCCT-SCEEE-B-CE.......-S-TTTTSS-SCECCE-CCC--CCCCCCHHHHHHCTT-EEEEEE--SC--TTSCCCHCCHH CS
  Alpha-amylase   1 GDLkGiiekLdYlkeLGvtaiwlsPifk.......spqadhgYdiadytkidpefGtnedlkeLiskahekgikvilDlVvNHtsdehewfkeslk 89 
                    G++ G+ +kLdY+++LG+ta+ +sPi +       + +a hgY+ ++ + ++ +fGt++dlk+L+s++h++++++++D+V+N  +++      +++
     EEA22046.1  56 GTWSGLMSKLDYIQDLGFTAVQISPIQEnlpeetiYGEAFHGYWPQNLYGLNAHFGTADDLKHLVSELHKRDMYLMVDVVANELAYSIGQT--NMT 149
                    89*********************************999************************************************99954..444 PP

                    STTSGGGCCC-E......ESS-STTC-TTTTCSCEECTTTTCEEESSS-TTS-BB-TTTCCCCCCCCC.CCCCCCTTT-SEEEETTCCCTTTCCCC CS
  Alpha-amylase  90 kkgepkrdyyiwkegkeekeppnnwkslfdgsaweydekaqeyylhlflkklpdLnteneevrkelkd.vvkfwlekgidGfRlDvvkhvskveal 184
                     ++ +  dy ++ +     ++ ++  s+    +w++ +++   +l ++    p ++t+++++   l + ++ ++   +idG+R+D +k+++     
     EEA22046.1 150 ADNTTIIDYSAFAPF----NQSSDFTSYCPILDWSNATESTHCWLGYEGVATPRIKTTEPTIASTLDQwIADLVGTYDIDGIRIDGAKQIES---- 237
                    455568888886655....455666677888899998888888999999999****************9999999999**************.... PP

                    HCCHCCHHHHHHHHHHHTCCGTT-EEEEE-TT-SCCCHCCCC-CGG-SICECCITTCGGGCC-CTSTTSB-SS-HHHHHHHHHHHHHHS-CCCTTC CS
  Alpha-amylase 185 esngeflheftqalnetvasrkevmtvgEvssdasedlrvyttearlelemvldfphldvaqkakikeqlksisakklkellkkwlkaleeaaeea 280
                         f h+f + +         v+ +gEv++++ + l +y++ +   le   ++  ++   +a+     +  ++++l +++  +++a++   +  
     EEA22046.1 238 ----SFFHNFIESAG--------VYAMGEVYDGDAKFLCGYQSLTSG-LE---NYALYGKIIEAF-----TAGKMADLVAMVGAMRQACHS-PQYL 311
                    ....*******9999........678******999866666544332.23...344444333333.....56679***************8.9999 PP

                    EEES--TTS--HHHHTTSSTTTTHHHHHHHHHCCCTSSSEEEEETTCCCT---- CS
  Alpha-amylase 281 vtflgnHDqeRilsrlgddsaeaekklklaaillltlrGvpviYyGeEigmtgg 334
                    ++f++n D++R++s ++d +      +k+a++++++++G+p  YyG+E+++ g 
     EEA22046.1 312 ANFIENQDNPRFASLTQDIA-----LAKNALAFTILSDGIPKMYYGQEQHLPGN 360
                    ****************9999.....8***********************99875 PP

>> DUF1966  Domain of unknown function (DUF1966)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.2   0.0     2e-27   1.2e-23       2      90 .]     409     497 ..     408     497 .. 0.94

  Alignments for each domain:
  == domain 1  score: 83.2 bits;  conditional E-value: 2e-27
     DUF1966   2 lysdkstlalrKgpegsqvvtvlsnkGssgssytlslkssgyaagtevvdvlsCks.vtvdssgeltvtmekGePrvlvpksklegsglC 90 
                 ly+d st+a+rKgp+++q+v+vlsn+G +g+ ytl+++     +gt++++v  C s v ++++g +tv+m +G+Prv++p+ +l+gsglC
  EEA22046.1 409 LYTDGSTYATRKGPNEAQIVAVLSNQGLQGGDYTLQVP-GVADSGTNLTEVTLCDStVIAGENGTITVPMGHGQPRVYYPTFNLNGSGLC 497
                 8*************************************.56699**********751678****************************** PP

>> UBA_6  UBA-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.0   0.00024       1.4       3      29 ..      63      89 ..      62      91 .. 0.91
   2 ?    3.2   0.0     0.014        82      10      27 ..     419     436 ..     415     440 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00024
       UBA_6  3 skldfflKLGYseeqvqavLekLGpea 29
                skld+   LG++  q+  ++e+L  e+
  EEA22046.1 63 SKLDYIQDLGFTAVQISPIQENLPEET 89
                699*******************97665 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.014
       UBA_6  10 KLGYseeqvqavLekLGp 27 
                 + G  e+q++avL++ G+
  EEA22046.1 419 RKGPNEAQIVAVLSNQGL 436
                 556689********9886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (556 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       442  (0.0246528); expected 358.6 (0.02)
Passed bias filter:                      356  (0.0198561); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 3703.10
//
Query:       EEA22047.1  [L=325]
Description: 4-hydroxybenzoate octaprenyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.3e-27   94.7  15.6    7.9e-27   94.2  15.6    1.4  1  UbiA      UbiA prenyltransferase family


Domain annotation for each model (and alignments):
>> UbiA  UbiA prenyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.2  15.6   4.4e-31   7.9e-27      20     225 ..      69     286 ..      40     313 .. 0.78

  Alignments for each domain:
  == domain 1  score: 94.2 bits;  conditional E-value: 4.4e-31
        UbiA  20 llllllllgtllaaaaanalNdyfDreiDadmertpnRPlvsGrispkealifaivllilgllllalllnpltallgllalllyvvYtglrlKrrtllg 118
                 +l+   +l ++ ++ a +a+ d +D+e+D++++r++ RP+++ +++p+ea+ f+ +ll +g l l ++l   + +lg++++l+  +Y+  + Kr+t+++
  EEA22047.1  69 RLVSRSVLWVYYMRHALCAFKDAVDYEFDRRVRRRQSRPVARWALTPEEAFNFSSILLHIGTLGL-FFLPSESHGLGVIVILVMMLYP--FGKRFTFFP 164
                 77888899999******************************************************.**********************..********* PP

        UbiA 119 tvvggiafglppllgwaavtgsl......sllalllalavflltwaialandlrdregDrkagiktlpvvlGrkaarillalllavllla......... 202
                 +++ g+ f+l +++   +++ +l       + al l++ ++ll++   +++ ++d+++D++ag k++++ + ++  ++ l++++av+ ++         
  EEA22047.1 165 QFIMGFGFTLSVFMSGKVIGVDLspgsedFWSALYLGIVCMLLATIANVVYTYQDMRDDAQAGGKSMALMMSNRPKIW-LWAMTAVVEVLlwkignlsd 262
                 ****************************55555555555555555555566***************************.55455555444335555555 PP

        UbiA 203 .llllllalllllylllalllaal 225
                   +l+ +   ++  ++l++l+a++
  EEA22047.1 263 ySILYNIITCGGSSFALSALVALV 286
                 544444444444444444444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (325 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       701  (0.0390987); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 2206.00
//
Query:       EEA22048.1  [L=419]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.1e-11   42.4  18.5    4.3e-10   39.1  10.6    2.5  3  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
       0.49   10.4   2.0       0.65   10.0   0.4    2.1  2  DUF5345   Family of unknown function (DUF5345)
        4.9    7.1  10.0        2.1    8.3   0.2    2.8  2  Caveolin  Caveolin


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.4   0.0   0.00015      0.91      16      73 ..      95     157 ..      85     161 .. 0.80
   2 !   39.1  10.6   7.2e-14   4.3e-10     158     353 .]     169     372 ..     166     372 .. 0.74
   3 ?   -2.4   0.2       0.3   1.8e+03      55      81 ..     380     406 ..     378     412 .. 0.59

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00015
       MFS_1  16 gpalplalaedlgispseigllltlyalgaavaslplGrlsd....r.fGrrrvlllglllfa 73 
                 ++  p  +  +l+ + ++++ + ++y++ ++++ lp   l      r f  r ++++g++l +
  EEA22048.1  95 AVGKPTNILAQLQRTSDQYNSVQSIYYISYIIFELPSNLLLKwmkpRlFQTRVCFIWGFVLAC 157
                 5555665667788899************************99888844778889999998876 PP

  == domain 2  score: 39.1 bits;  conditional E-value: 7.2e-14
       MFS_1 158 aivsllafvlfllllpeepperkrkspkeee............kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsgll 244
                 a++++++ v  +  +p++p++ ++ +p+e+e              +  +++++a+  ++  + lw++++a +++ +g +gl+ +lp++  + lg+ gl 
  EEA22048.1 169 AFAGIVFTV--YPDYPRSPRSAQWLTPREQEfiekrladntprTDDSLFSWRKAIDTIRDVR-LWSFMLAQVCMNIGGFGLTWFLPTI-ITNLGFVGLP 263
                 333333322..244599999999999999989999888888776666666666555555555.999999999999************7.*******655 PP

       MFS_1 245 laglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdla.ppeeagtasglfn 342
                  + ll+  ++++g+i+ ++a+++ +r  + +r +l+l++++l  + +a++ +t +  ++++++vl ++ +++  ++++a+ ++++ ++  +++a++l +
  EEA22048.1 264 RNQLLVIPPSAAGIIAIVVAAYVFKR-AWLPRPVLTLVIVALEIITFAIFLATRTRGAIYAACVLGTMLSACLAIPFWAWRTSSLkGTTGTAFAMSLQS 361
                 66655677777776666666666666.66666777777777777777777777668888889999888999999999999888885667777******* PP

       MFS_1 343 tagslggalgp 353
                  +g+lgg++gp
  EEA22048.1 362 GVGQLGGVIGP 372
                 **********8 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 0.3
       MFS_1  55 lsdrfGrrr.vlllglllfalglllllf 81 
                  +dr+ r +  +++g+l+ ++ + +l++
  EEA22048.1 380 AADRY-RVSyAVCVGALWGCFLFNCLSW 406
                 57777.6665666666666666444444 PP

>> DUF5345  Family of unknown function (DUF5345)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.1      0.55   3.3e+03      12      30 ..      11      29 ..       8      41 .. 0.67
   2 ?   10.0   0.4   0.00011      0.65      15      62 ..     270     317 ..     265     333 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.55
     DUF5345 12 ievetPsleeleqllaeek 30
                ++ ++ s e++eq+  +++
  EEA22048.1 11 VDSPSSSAEDIEQQQVSAA 29
                5566678899988765554 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00011
     DUF5345  15 etPsleeleqllaeekerkrkrlrrElllFlliAllilsllllalvqa 62 
                   Ps + + +++ ++   kr  l r +l ++++Al i+++ ++++++ 
  EEA22048.1 270 IPPSAAGIIAIVVAAYVFKRAWLPRPVLTLVIVALEIITFAIFLATRT 317
                 569999*************************************99875 PP

>> Caveolin  Caveolin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   0.2   0.00034       2.1      34      83 ..     111     161 ..     102     163 .. 0.89
   2 ?    0.9   4.6      0.07   4.2e+02      64     103 ..     267     308 ..     265     336 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00034
    Caveolin  34 dsthsfdkvwrlshavfevvkvliYrllt.allaiPlalilgilfallsal 83 
                 d   s+++++ +s+ +fe+   l+ + ++  l+   + +i+g+++a+ +++
  EEA22048.1 111 DQYNSVQSIYYISYIIFELPSNLLLKWMKpRLFQTRVCFIWGFVLACHATV 161
                 56789*******************9999746999************98776 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.07
    Caveolin  64 llaiP..lalilgilfallsalhiwlvvPlvklllielkliq 103
                 ll iP   a i++i++a   +   wl  P++ l++++l++i+
  EEA22048.1 267 LLVIPpsAAGIIAIVVAAYVFKRAWLPRPVLTLVIVALEIIT 308
                 566663335689************************999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (419 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       884  (0.0493056); expected 358.6 (0.02)
Passed bias filter:                      534  (0.0297841); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 2932.52
//
Query:       EEA22049.1  [L=407]
Description: salicylate hydroxylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      4e-08   32.9   0.0    1.3e-07   31.2   0.0    1.7  2  FAD_binding_3  FAD binding domain
      2e-07   30.4   0.5     0.0004   19.6   0.0    2.2  2  Lycopene_cycl  Lycopene cyclase protein
    9.6e-07   28.3   0.8     0.0056   15.9   0.1    2.2  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    2.9e-06   27.1   0.1       0.02   14.5   0.1    2.2  2  DAO            FAD dependent oxidoreductase
    1.4e-05   25.2   0.1    7.9e-05   22.8   0.0    2.2  2  NAD_binding_8  NAD(P)-binding Rossmann-like domain
    0.00034   20.6   1.5       0.26   11.3   0.0    3.1  3  NAD_binding_9  FAD-NAD(P)-binding
     0.0022   16.8   0.2     0.0044   15.8   0.2    1.5  1  HI0933_like    HI0933-like protein
     0.0033   16.7   0.5        1.2    8.4   0.1    2.4  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
     0.0034   16.7   0.4       0.02   14.2   0.1    2.1  2  Amino_oxidase  Flavin containing amine oxidoreductase
     0.0054   17.3   1.2       0.17   12.4   0.2    2.6  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
      0.016   14.4   0.1      0.028   13.6   0.1    1.4  1  Thi4           Thi4 family
      0.077   12.1   1.2        0.1   11.6   0.3    1.6  2  FAD_binding_2  FAD binding domain
       0.22   11.3   1.6       0.38   10.6   1.6    1.3  1  zf-HYPF        HypF finger


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.2   0.0   9.3e-11   1.3e-07       4     250 ..       5     249 ..       3     289 .. 0.65
   2 ?   -1.3   0.0      0.73     1e+03     298     322 ..     302     326 ..     297     328 .. 0.81

  Alignments for each domain:
  == domain 1  score: 31.2 bits;  conditional E-value: 9.3e-11
                    EEEE--SHHHHHHHHHHHHTT.HHEEEEESSSSSCCSSS--EEEHHHHHHHHHTT-HHHHHHHSEECCCCEEEEEEE...CCCCCEEEEEHHCHHC CS
  FAD_binding_3   4 VlIVGaGpaGlmlallLseaG.vrvvlvekrsttvvlpradglnqrtmellrqlGledrilaegapnelmgealyne...lsdtpkaradleless 95 
                     +IVGaG  Gl+la  L++    +v l e+ s+  + +   g+ +  +++l++lG+e+ + +e   ++ +g+ +  +    +++    +++++  +
     EEA22049.1   5 LAIVGAGVGGLTLAIALKQNPnLSVQLYERASELKEIGALVGVGPNALRTLEKLGVEEALTDEVGWRNPNGIPMIFRhwkTGELLSKDEYHNATNR 100
                    57***************9984156888888888888888899******************998655554454444442112444444444445667 PP

                    ST-CEE--HHHHHHHHHHHHHHHT.EEETCSEEEECCEE.CCCCCCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHHHTGG..EEEEEEEEEEEE CS
  FAD_binding_3  96 pervtvypqteleriLvehaeerg.lqvrfktevesleq.deegvtaevrdketgeeetvrakYlvGaDGgrStvrktlgie..fegeetvyeagv 187
                      +++ +   +l+++++++    g + ++ +++v +++   e gvt ++        +t++ + ++GaDG +S+vr++   +  ++  ++     v
     EEA22049.1 101 RHHYARMHHAKLQKAMLSK--LNGeVPIHLGKKVSTVTVvRERGVTVTFEHG-----TTISTDVVIGADGIKSRVRRSFVPDhkLNWLGD----VV 185
                    7777777888888888888..4455666666666644431445666655544.....48*****************99764311222222....23 PP

                    EEEEEEC.-SCCCTTC.CEEEEECCTTEEEEEECCETEEEEEEEEECCE-GGGSCCCHHHHHHHH CS
  FAD_binding_3 188 ldvlfda.dlsdivep.lvlilsaesrgvmviPlentlerfyvqvearaekeersekfteeevka 250
                    l ++fd   ++di e  +   + + ++g+ ++ +   ++ f v +++  + e+++e+f e++  a
     EEA22049.1 186 LRTTFDYyVITDIKEIpQNSSHFSGPQGFFFGTRMG-SNGFGVTCSFAVDPESKTEPFHEQVWNA 249
                    333333333333322234445555555545555554.6777777777777777777777776655 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.73
                    STTSHHHHHHHHHHHHHHHHHHHHH CS
  FAD_binding_3 298 PtgGqGlNtaiqDavnLawkLaavl 322
                    + g  G+ +ai Da+ L +++  vl
     EEA22049.1 302 VHGPAGVGLAIDDAYALSRAFETVL 326
                    566679999********99887776 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.0   0.1   0.00045      0.62       2      33 ..       5      35 ..       4      42 .. 0.89
   2 !   19.6   0.0   2.9e-07    0.0004      61     145 ..      82     168 ..      71     186 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00045
  Lycopene_cycl  2 vvviGaGpAglslAarlteakpglkvvlieas 33
                   ++++GaG  gl lA  l +++p+l+v l e +
     EEA22049.1  5 LAIVGAGVGGLTLAIAL-KQNPNLSVQLYERA 35
                   79***************.9*******998765 PP

  == domain 2  score: 19.6 bits;  conditional E-value: 2.9e-07
  Lycopene_cycl  61 sWsgtivylddgkkillg..raYgrvsskrlkeellerlvengvklleakvesveeeeageslvvleggrkirarlvvdarglaslk 145
                     W+  ++  +d+ +   +    Y+r++ ++l++ +l +l  +  + l  kv  v+ + +  ++v+ e g +i   +v+ a g+ s+ 
     EEA22049.1  82 HWKTGELLSKDEYHNATNrrHHYARMHHAKLQKAMLSKLNGEVPIHLGKKVSTVTVVRERGVTVTFEHGTTISTDVVIGADGIKSRV 168
                    5776666666655555443478******************7777888999****9999999*********************87765 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.1   4.1e-06    0.0056       2      31 ..       4      38 ..       3      71 .. 0.82
   2 !   10.9   0.1   0.00014      0.19     174     239 ..     101     166 ..      87     185 .. 0.88

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 4.1e-06
                 SEEEE--SHHHHHHHHHHHHH.TS-EEEEE....T CS
                 xxxxxxxxxxxxxxxxxxxxx.xxxxxxxx....x RF
  Pyr_redox_2  2 dvvviGgGpAGlaaaltlaqa.gakvtlve....l 31
                 +++++G+G++Gl++a+ l+q+ ++ v l+e    l
   EEA22049.1  4 QLAIVGAGVGGLTLAIALKQNpNLSVQLYEraseL 38
                 579*****************66*******744441 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00014
                  SSSSSTTS-HHHHHHHHHHHHHTTEEEEESCEEEEEEETTE.EEEEEETTSCEEEESEEEE-S-EEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 174 rdrllraldkelsaaleealekeGvevklgtsvkeidgnge.klevvledgeeidadlvvvavGvrp 239
                  r +  r++  +l++a+  +l+   v ++lg++v +++   e  ++v+ e g++i +d v+ a G++ 
   EEA22049.1 101 RHHYARMHHAKLQKAMLSKLNG-EVPIHLGKKVSTVTVVRErGVTVTFEHGTTISTDVVIGADGIKS 166
                  4455589999999999999998.6***********9999998999****************999876 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.1   1.5e-05      0.02       2      32 ..       5      38 ..       4      44 .. 0.88
   2 !   10.8   0.0   0.00019      0.27     107     237 ..      72     206 ..      52     281 .. 0.64

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 1.5e-05
                EEEECTSHHHHHHHHHHHHTT...EEEEESSSST CS
         DAO  2 vviiGGGiiGlstAyeLarrg...Vtllekgdia 32
                ++i+G+G+ Gl+ A +L + +   V l+e+++++
  EEA22049.1  5 LAIVGAGVGGLTLAIALKQNPnlsVQLYERASEL 38
                68***************887789*******9876 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00019
                 HHTTTTE..E.EEEHHHHHHHSTTSTTTSEE.EEETTEEEEEHHHHHHHHHHHHHHTT-EEEESECEEEEEEEETCEEEEEEECT.EEEEEEEEEEE-- CS
         DAO 107 leaglda..e.lldaeevrelepalpgllga.lfypdtgqvdpakltaalaraaealGveilegtevtgleeedgkvwgverttp.gendaadavVnaa 200
                 +++g++   + + ++e ++ ++     ++ a    ++ ++++ akl +a+++++  + v i++g +v  +   ++++++v  t + g++ + d v+ a 
  EEA22049.1  72 NPNGIPMifRhWKTGE-LLSKDE----YHNAtNRRHHYARMHHAKLQKAMLSKLN-GEVPIHLGKKVSTVTVVRERGVTV--TFEhGTTISTDVVIGAD 162
                 5666654444244444.444442....22221234556889************95.55******9999996666678888..444487744499***** PP

                 GGGHH..HHHTT...CTT....TSEEEEEEEEEEEEEECCT.HSTGS CS
         DAO 201 Gawsd..llgll...kel....dlpispvrgqvlvlkplse.klvsp 237
                 G+ s+      +   ++l    d+ ++ +  +++ +  ++e +++s+
  EEA22049.1 163 GIKSRvrR--SFvpdHKLnwlgDVVLRTTFDYYVIT-DIKEiPQNSS 206
                 ***98542..33333334666777878888888888.6666222222 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8   0.0   5.7e-08   7.9e-05       1      30 [.       7      37 ..       7      38 .. 0.94
   2 ?   -1.1   0.0       1.7   2.3e+03      30      54 ..     127     156 ..     126     168 .. 0.76

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 5.7e-08
                   EE--SHHHHHHHHHHHCC.TEEEEEE-SSSS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLaka.gfdvlllekrdr 30
                   IvGaG++Gl++A +L+++ +++v+l+e+++ 
     EEA22049.1  7 IVGAGVGGLTLAIALKQNpNLSVQLYERASE 37
                   9****************99********9976 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 1.7
                    SSSGGG-EECE...TT..CEECTS---EEE CS
  NAD_binding_8  30 rlGGraasyev...pg..vrvdygahifhg 54 
                    +lG ++++++v    g  v++++g +i ++
     EEA22049.1 127 HLGKKVSTVTVvreRGvtVTFEHGTTISTD 156
                    566677777776544578999999998776 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.3   0.0   0.00019      0.26       1      35 [.       6      36 ..       6      41 .. 0.88
   2 ?    2.5   0.0     0.096   1.3e+02       1      17 [.      43      59 ..      43      71 .. 0.87
   3 ?    4.5   0.1     0.023        31      86     154 ..      99     163 ..      72     165 .. 0.60

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00019
  NAD_binding_9  1 aivGaGprGlavlerLlarakkkspleitlfdpse 35
                   aivGaG+ Gl+++ +L ++     +l+++l+++++
     EEA22049.1  6 AIVGAGVGGLTLAIALKQNP----NLSVQLYERAS 36
                   8***************9995....99999999965 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.096
  NAD_binding_9  1 aivGaGprGlavlerLl 17
                   a+vG Gp +l +le+L 
     EEA22049.1 43 ALVGVGPNALRTLEKLG 59
                   79************995 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.023
  NAD_binding_9  86 dpddfvpRalyGrYlrdlfeellarlpegvtvevhraevvdlee.radgqavlladgaslaadaVvLAlG 154
                    +++++  R +  + +++++++l  ++p    +++  ++v  ++  r++g++v+ ++g+++  d V+ A G
     EEA22049.1  99 NRRHHYARMHHAKLQKAMLSKLNGEVP----IHL-GKKVSTVTVvRERGVTVTFEHGTTISTDVVIGADG 163
                    444444444444444444444444443....332.4455555551445679999***********97765 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.2   3.2e-06    0.0044       2     166 ..       4     166 ..       3     169 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 3.2e-06
                  SEEEE--SHHHHHHHHHH.HHTT--EEEE-SSSSS-HHHHHCGGGT-EE.EETT-SGGGEEES...STTTTHHHHHHS-HHHHHHHHHHTT--EEE-S CS
  HI0933_like   2 dviviGgGaAGlmaAisa.akrgkrVlllekakklgrKilisGgGrcNv.Tnlseepeellsrypenpkflksalsrftnedlialveelgvelkeed 97 
                  +++++G+G  Gl  Ai++ ++ + +V l+e+a++l +  ++ G G   + T ++  +ee l+    + +  + +   f+++++ +l+++   e++  +
   EEA22049.1   4 QLAIVGAGVGGLTLAIALkQNPNLSVQLYERASELKEIGALVGVGPNALrTLEKLGVEEALTD-EVGWRNPNGIPMIFRHWKTGELLSKD--EYHNAT 98 
                  579***************667899**********999999*****988734467777777766.33444444444456666666666665..355555 PP

                  TTEEEETT.-CHHHHHHHHHHHHHHT-EEE-S--EEEEECETTE.EEEEE.TTEEEEESEEEE----SS CS
  HI0933_like  98 sgrlFpvsdkaedivdallkelkeagvklrletevksvekeedgkfrvktkseeeleadklvlAtGGlS 166
                  + r   ++++ +++ +a+l++l+  +v ++l ++v++v+  +++ ++v+ ++++++++d ++ A G +S
   EEA22049.1  99 NRRHHYARMHHAKLQKAMLSKLN-GEVPIHLGKKVSTVTVVRERGVTVTFEHGTTISTDVVIGADGIKS 166
                  55666666666779999999997.68******************9*****9999999999998988776 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.4   0.1   0.00085       1.2       2      28 ..       7      33 ..       6      41 .. 0.83
   2 !    6.3   0.1    0.0035       4.9      77     133 ..     103     163 ..      82     177 .. 0.67

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00085
  Pyr_redox_3  2 IiGaGPaGlaaaielkkagledylilE 28
                 I+GaG  Gl+ ai+lk++   ++   E
   EEA22049.1  7 IVGAGVGGLTLAIALKQNPNLSVQLYE 33
                 9***************99876666555 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0035
  Pyr_redox_3  77 klsrkealeYlrevaksf..elpiklfeeVesvkk.edegfevetske.tyeAkkviiAtG 133
                  + +r+  ++  +++ ++   e+pi+l ++V +v+   ++g +v+ +++ t++++ vi A G
   EEA22049.1 103 HYARMHHAKLQKAMLSKLngEVPIHLGKKVSTVTVvRERGVTVTFEHGtTISTDVVIGADG 163
                  4555555555554444431268899999999998866788999988884555555555555 PP

>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0      0.31   4.3e+02       2      23 ..      13      35 ..      12      38 .. 0.90
   2 !   14.2   0.1   1.4e-05      0.02     215     259 ..     115     161 ..      92     182 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.31
                   HHHHHHHHHHHTT.EEEEEEESS CS
  Amino_oxidase  2 aGLaaArqLlsaG.fdVtvlEar 23
                    GL+ A  L+++  ++V+++E  
     EEA22049.1 13 GGLTLAIALKQNPnLSVQLYERA 35
                   6********************75 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 1.4e-05
                    HHHH.TTTTEEEETSEEEEEEEE.ETTCEEEEETTSTEEEESEEEE- CS
  Amino_oxidase 215 alae.elrgldirlntrVkeikr.egdgvtvtledgevveaDaVvvT 259
                    a+ +   +++ i+l+++V+ ++   + gvtvt+e+g++++ D V+ +
     EEA22049.1 115 AMLSkLNGEVPIHLGKKVSTVTVvRERGVTVTFEHGTTISTDVVIGA 161
                    55554556789************9*******************9965 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.4   0.2   0.00013      0.17       2      44 ..       5      43 ..       4      68 .. 0.77
   2 ?    3.1   0.1      0.11   1.5e+02      42      79 ..     112     148 ..      99     154 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00013
                EEEECSSHHHHHHHHHHHH.TTSEEEEEESSSSSSTTSSHHHHH CS
   Pyr_redox  2 vvvvGgGyiglElAgalae.lgkkVtvversdkllrllDeeask 44
                +++vG+G+ gl lA al++  + +V++ er+++l      e+++
  EEA22049.1  5 LAIVGAGVGGLTLAIALKQnPNLSVQLYERASELK-----EIGA 43
                79***************775889**********99.....4443 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.11
                 HHHHHHHHHHHTTEEEECSEEEEEEEEETTS.EEEEEEE CS
   Pyr_redox  42 askilqeklekngievllntkveeiegsedg.vesvklk 79 
                 ++k++  kl  + + ++l++kv  ++   +  v+ v+++
  EEA22049.1 112 LQKAMLSKLNGE-VPIHLGKKVSTVTVVRERgVT-VTFE 148
                 555555666555.************965554366.7765 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   2.1e-05     0.028      20      50 ..       5      35 ..       1      48 [. 0.91

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 2.1e-05
                EEEE--SHHHHHHHHHHHHCTTS-EEEEESS CS
        Thi4 20 vvivGaGssGLtaayylakkpdlkvailers 50
                ++ivGaG  GLt a  l ++p+l v + er 
  EEA22049.1  5 LAIVGAGVGGLTLAIALKQNPNLSVQLYERA 35
                68*************************9985 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.3   7.5e-05       0.1       3      32 ..       6      36 ..       4      62 .. 0.88
   2 ?   -1.6   0.0      0.79   1.1e+03      85     151 ..      44     120 ..      31     168 .. 0.48

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 7.5e-05
                   EEE--SHHHHHHHHHHHHTTT.-EEEEESSS CS
  FAD_binding_2  3 iViGsGlAGLaAAleaaeaGl.kvavvekeq 32
                    ++G+G++GL+ A++++++   +v + e ++
     EEA22049.1  6 AIVGAGVGGLTLAIALKQNPNlSVQLYERAS 36
                   79****************8776998887766 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.79
                    HHHTHHHHHHHHHHTT----BCCTS..........SB-EEE-TT-SSTEEEE-.STT-.......HHHHHHHHHHHHH CS
  FAD_binding_2  85 fveaapeavdeLeelgvpfsrtedg..........pvdvrelGglsatartlhdaadarr.etlvtghallarlvesa 151
                    +v  +p a++ Le+lgv    t++            ++  + G+l  + +++  a ++r   + + + +l ++++ ++
     EEA22049.1  44 LVGVGPNALRTLEKLGVEEALTDEVgwrnpngipmIFRHWKTGELLSKDEYHN-ATNRRHhYARMHHAKLQKAMLSKL 120
                    55566677777777755544411112222222444333333444444423333.222222222223333444444444 PP

>> zf-HYPF  HypF finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   1.6   0.00028      0.38       7      20 ..      92     105 ..      91     107 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00028
                 HHHC-TTSTTTT-T CS
     zf-HYPF   7 rEykdpldRRfhaq 20 
                  Ey++ ++RR+h+ 
  EEA22049.1  92 DEYHNATNRRHHYA 105
                 6************5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (407 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       592  (0.0330191); expected 358.6 (0.02)
Passed bias filter:                      532  (0.0296726); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.59u 0.32s 00:00:00.90 Elapsed: 00:00:00.46
# Mc/sec: 2664.13
//
Query:       EEA22050.1  [L=749]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.7e-17   63.4   0.1    3.7e-17   62.2   0.0    1.6  2  Fungal_trans  Fungal specific transcription factor domain
     0.0011   19.1  12.5     0.0019   18.3  12.5    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.2   0.0   4.1e-21   3.7e-17       2     266 ..     240     485 ..     239     486 .. 0.82
   2 ?   -2.9   0.1      0.31   2.8e+03      46     111 ..     521     582 ..     511     584 .. 0.68

  Alignments for each domain:
  == domain 1  score: 62.2 bits;  conditional E-value: 4.1e-21
  Fungal_trans   2 drffsnfhpqfpilhkpsflpkt....ssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwil 94 
                   + +f+++h   p+l+k + +++     ++ ++++ ++ s+ l  +  + Ga +++ ++ ++   + + +      p++  i+    +    + ++++
    EEA22050.1 240 KGYFDHVHKSSPFLNKIKTMEEVdivlRQMRNTNGRHVSTKLYMLAAIGGAALKHANKIRT-EIAAKLV-----VPYQSIICE---CIEMEN-VCSI 326
                   56**************666666668866666667777766666666666666666666555.4444433.....355766666...666666.**** PP

  Fungal_trans  95 qsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcdddd 191
                   + Llll+ly++   d    + + g+  r   slgLhr+  + +k     l++e+ e r Rl+w+ F lD+ +a+ +G p+ ++d +i+lpLP    +
    EEA22050.1 327 EILLLLALYSLYDPDGLNPWVLTGILGRQIISLGLHRRILRPEK---SGLTAEDTELRARLFWSSFELDRVVASSYGLPVAINDANIDLPLPGVTLE 420
                   *************************************9999886...4699999**************************89**********77776 PP

  Fungal_trans 192 lwesddaseetlvetklsneeksrkiasfllaLkkilskiagsllsiekqlqqrdlqseklswveeleraldnWr 266
                   +  ++d ++ +             + + +++aL  + + i+  ++  ++ ++   ++s+ +  +++l+ ++dnW+
    EEA22050.1 421 EFAASDLRYYRETL----------QVSRSVVALRDLEGRILQRIHLSNSASDTALSRSDCDIIIKDLRLQIDNWY 485
                   66666666666655..........7899**************999999999999999*****************7 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.31
  Fungal_trans  46 lGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLlllelyektssdra 111
                   ++++f ++ ++++  +l++    +i++++r + +++e+   +++++++   L+++++ ++++ +++
    EEA22050.1 521 TPSQFNSKLSRKQLVNLRR----TIQQYIRCALVLLEQGHLSFNRVTVGRLLVIAAIMLFCFRRQR 582
                   4444444444444444444....6666668888888888888888888888888888888887765 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3  12.5   2.1e-07    0.0019       2      33 ..      79     109 ..      78     116 .. 0.88

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 2.1e-07
                 S-HHHHHCT---STSSSS-HHHHHCTHHHCCC CS
     Zn_clus   2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfy 33 
                 aC++Cr  K+KC +  P+C+ C+  ++ C+  
  EEA22050.1  79 ACKRCRHMKRKCCRTLPECTPCVAAGYICS-W 109
                 9****************************9.3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (749 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       654  (0.0364772); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.68u 0.34s 00:00:01.02 Elapsed: 00:00:00.53
# Mc/sec: 4218.97
//
Query:       EEA22051.1  [L=574]
Description: monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.7e-13   48.1   1.1    2.2e-09   36.3   0.1    2.8  3  FMO-like       Flavin-binding monooxygenase-like
    1.2e-11   44.7   0.7    3.5e-11   43.2   0.0    2.3  2  NAD_binding_8  NAD(P)-binding Rossmann-like domain
    1.4e-09   37.6   0.0      2e-08   33.9   0.0    2.1  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    2.1e-08   33.8   0.0    0.00072   18.9   0.0    3.1  3  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
    0.00097   18.4   0.1     0.0026   17.1   0.1    1.6  1  Thi4           Thi4 family
      0.002   18.1   0.7       0.67    9.9   0.0    3.3  3  NAD_binding_9  FAD-NAD(P)-binding
     0.0022   17.2   0.2      0.048   12.8   0.0    2.8  4  K_oxygenase    L-lysine 6-monooxygenase (NADPH-requiring)
  ------ inclusion threshold ------
       0.16   10.5   0.0        4.8    5.6   0.0    2.1  2  Mqo            Malate:quinone oxidoreductase (Mqo)


Domain annotation for each model (and alignments):
>> FMO-like  Flavin-binding monooxygenase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.0   0.0   0.00018       0.4       3      41 ..      41      81 ..      40     103 .. 0.80
   2 !   36.3   0.1   9.7e-13   2.2e-09     113     221 ..     116     228 ..     108     236 .. 0.87
   3 ?   -0.7   0.0      0.16   3.7e+02     303     334 ..     346     376 ..     331     384 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00018
    FMO-like  3 kvaviGaGvsGla.sikcc.leegleptcfersddiGGlwr 41
                k+ ++GaG+ G+a si       +le + +e++d +GG w 
  EEA22051.1 41 KLIIVGAGIGGIAaSILISnKVPNLEYVVYEKTDAVGGTWT 81
                6789*******9625544304469****************6 PP

  == domain 2  score: 36.3 bits;  conditional E-value: 9.7e-13
    FMO-like 113 kkrpdfstsGqwev..vtekegkkesavfdavmvctGhhvnphlple.sfpGie.kfkGqyfhsrdykepevfkgkrvlviGlGnsggdiavelsrtae 207
                 ++ +   +  qw v       gk+ +++   v+  +G +  p++p +   pGi+ +fkG+y h+ d+ +   +kgkr+ +iG G sg ++ +++ + a 
  EEA22051.1 116 TRATWIDEISQWSVeiLNLITGKTFTEIAHFVVSAAGRLNVPKMPDDkQIPGIRtEFKGHYRHTADWDTNYDWKGKRIAIIGNGASGQQLLSNMVKDAG 214
                 555556677899662156679************************86379***747******************************************* PP

    FMO-like 208 qvllstrsGswvls 221
                 +v    rs  w+l 
  EEA22051.1 215 HVDHYVRSKQWILP 228
                 ***********996 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 0.16
    FMO-like 303 keltetsaifedgtveedidvvifatGytfaf 334
                    t +  +  dgtv e +d++i atG+   f
  EEA22051.1 346 VGATGNGLVTADGTVRE-VDAIIAATGFQNGF 376
                 55677778889999875.9********97665 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.2   0.0   1.6e-14   3.5e-11       1      58 [.      44     103 ..      44     110 .. 0.95
   2 ?   -3.5   0.2       5.8   1.3e+04       1      12 [.     345     356 ..     345     357 .. 0.90

  Alignments for each domain:
  == domain 1  score: 43.2 bits;  conditional E-value: 1.6e-14
                    EE--SHHHHHHHHHHHCC..TEEEEEE-SSSSSSGGG-EECETTCEECTS---EEETTHH CS
  NAD_binding_8   1 IvGaGlsGlvaAylLaka..gfdvlllekrdrlGGraasyevpgvrvdygahifhgsgyy 58 
                    IvGaG++G +a  l++++  +++ +++ek d +GG ++ +++pgvr+d++ hi+h +++y
     EEA22051.1  44 IVGAGIGGIAASILISNKvpNLEYVVYEKTDAVGGTWTQNRYPGVRCDVPSHIYHVVEKY 103
                    9****************999***********************************99776 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 5.8
                    EE--SHHHHHHH CS
  NAD_binding_8   1 IvGaGlsGlvaA 12 
                    IvGa   Glv+A
     EEA22051.1 345 IVGATGNGLVTA 356
                    899999999998 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.9   0.0   8.8e-12     2e-08       2     185 ..      41     234 ..      40     241 .. 0.74
   2 ?    1.5   0.0     0.062   1.4e+02     212     238 ..     351     373 ..     330     400 .. 0.74

  Alignments for each domain:
  == domain 1  score: 33.9 bits;  conditional E-value: 8.8e-12
                  SEEEE--SHHHHHHHHHHHHH..TS-EEEEE.........TTHCHHHCSHHHHCHHHHHHHHHHHHHHHHHCHHHHCCCCHCCTCEEEEESCEEEEET CS
                  xxxxxxxxxxxxxxxxxxxxx..xxxxxxxx.........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2   2 dvvviGgGpAGlaaaltlaqa..gakvtlve.........legtclnggcllskallgvaedaeiasevvkklnqgielllgeevvkidpgkkkvkle 88 
                  +++++G+G++G+aa++ ++++  +++ +++e          ++  ++++c +++ + +v e++ +  +   +l++++++ +   + +i  ++  v++ 
   EEA22051.1  41 KLIIVGAGIGGIAASILISNKvpNLEYVVYEktdavggtwTQNRYPGVRCDVPSHIYHVVEKYGVKPNL--RLQHQVTRATW--IDEI-SQW-SVEIL 132
                  689*****************5559999999655555566666666666666666666666666544443..33444444333..4444.555.89999 PP

                  EEECTCEEEEEESEEEE---E..EE-BC...TCTTC.TTBEECCSECHHHHHHCCSS-TSEEEEES-SHHHHHHHHH.HHHHT-EEEEEESSSSSSTT CS
                  xxxxxxxxxxxxxxxxxxxxx..xxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  89 kkkegdeekiaydklvlAtGs..sprdl...gipGvaenvgklvrtldsaealklkllpkrivvvGgGyiGvElAaa.laklgkevtlveardrllra 180
                  ++ +g++++  ++ +v A G    p+ +   +ipG   + +k+    + +   +++++ kri+++G+G+ G  l +   +++g+  ++v   +++l+a
   EEA22051.1 133 NLITGKTFTEIAHFVVSAAGRlnVPKMPddkQIPGI-RTEFKGHYRHTADWDTNYDWKGKRIAIIGNGASGQQLLSNmVKDAGHVDHYVRSKQWILPA 229
                  9999****************5556666688899999.5555554567777788999****************98776478889989999999999999 PP

                  S-HHH CS
                  xxxxx RF
  Pyr_redox_2 181 ldkel 185
                  +  +l
   EEA22051.1 230 FSTNL 234
                  88766 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.062
                  TTEEEEEEETTSCEEEESEEEE-S-EE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 212 ngeklevvledgeeidadlvvvavGvr 238
                  ng    +v+ dg++ ++d ++ a+G++
   EEA22051.1 351 NG----LVTADGTVREVDAIIAATGFQ 373
                  33....677777777777777777765 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.2   0.3    0.0012       2.7       1      36 [.      43      80 ..      43      87 .. 0.77
   2 !   18.9   0.0   3.2e-07   0.00072     114     199 ..     132     225 ..     108     237 .. 0.79
   3 ?    3.6   0.0     0.014        32     205     271 ..     307     376 ..     289     392 .. 0.79

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0012
  Pyr_redox_3  1 iIiGaGPaGlaaaielkka.gledylilEkg.nignsi 36
                 iI+GaG  G+aa i + ++    +y++ Ek  ++g ++
   EEA22051.1 43 IIVGAGIGGIAASILISNKvPNLEYVVYEKTdAVGGTW 80
                 8************988665244589****996666555 PP

  == domain 2  score: 18.9 bits;  conditional E-value: 3.2e-07
  Pyr_redox_3 114 fevetske.tyeAkkviiAtGefdkPnkl...nipGeek.lvkhyskvkefh...kyagqkvvViGgknSavDaAlelvrkgaeVtvvtrgsei 199
                   ++ t k  t  A++v+ A+G+ + P+++   +ipG     + hy++  +++   + +g+++++iG + S+     ++v+   +V  ++r++++
   EEA22051.1 132 LNLITGKTfTEIAHFVVSAAGRLNVPKMPddkQIPGIRTeFKGHYRHTADWDtnyDWKGKRIAIIGNGASGQQLLSNMVKDAGHVDHYVRSKQW 225
                  5555666535569**********9999873336***99646779999998863225679*******************************9988 PP

  == domain 3  score: 3.6 bits;  conditional E-value: 0.014
  Pyr_redox_3 205 dpsyslkpdienrleelvke.ekikvlfnaevkeikekeeeykvk...tedgkkvevkddvvlatGykpdl 271
                  +   +lkpd+ +  ++l  + + ++++   +v+ i+++ +  + +   t+dg +v++ d +++atG+++ +
   EEA22051.1 307 EWFERLKPDYAPGCKRLTPSpGYLEAVISPKVEYIDQPIVGATGNglvTADG-TVREVDAIIAATGFQNGF 376
                  4456899999999999988888899999999999999887776555557786.5677799999****9876 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   0.1   1.2e-06    0.0026      19      58 ..      41      80 ..      34      84 .. 0.90

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 1.2e-06
                EEEEE--SHHHHHHHHHHHHC.TTS-EEEEESSSS--TTTT CS
        Thi4 19 DvvivGaGssGLtaayylakk.pdlkvailersvspGGGaw 58
                 ++ivGaG  G++a+  +++k p+l+ ++ e+  ++GG +w
  EEA22051.1 41 KLIIVGAGIGGIAASILISNKvPNLEYVVYEKTDAVGG-TW 80
                579*****************************999986.55 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.9   0.0    0.0003      0.67       2      60 ..      44      98 ..      43     137 .. 0.86
   2 ?    2.3   0.0     0.067   1.5e+02       1      20 [.     194     213 ..     194     221 .. 0.86
   3 ?    2.5   0.0     0.059   1.3e+02     132     155 ..     349     372 ..     332     373 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.0003
  NAD_binding_9  2 ivGaGprGlavlerLlarakkkspleitlfdpsepgagrvwrtdqseelllNvpasems 60
                   ivGaG+ G+a+   + ++     +le  +++++ +  g+ w +++ + ++  vp++  +
     EEA22051.1 44 IVGAGIGGIAASILISNK---VPNLEYVVYEKTDAV-GGTWTQNRYPGVRCDVPSHIYH 98
                   9*******9987765555...69***********99.9*******99999999987555 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.067
  NAD_binding_9   1 aivGaGprGlavlerLlara 20 
                    ai+G G++G  +l ++++ a
     EEA22051.1 194 AIIGNGASGQQLLSNMVKDA 213
                    8*************999986 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.059
  NAD_binding_9 132 dgqavlladgaslaadaVvLAlGh 155
                    +g  +++adg+  ++da++ A+G 
     EEA22051.1 349 TGNGLVTADGTVREVDAIIAATGF 372
                    4556899***************96 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0      0.42   9.4e+02       4      38 ..      41      75 ..      38      93 .. 0.79
   2 ?    1.2   0.0     0.075   1.7e+02     268     339 ..      84     152 ..      71     155 .. 0.79
   3 !   12.8   0.0   2.1e-05     0.048     117     226 ..     113     223 ..     104     241 .. 0.64
   4 ?   -0.4   0.0      0.22   4.9e+02     327     341 ..     359     373 ..     353     374 .. 0.85

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.42
  K_oxygenase  4 DligiGiGpsnLsLailleevkkelkalflerqpe 38
                  li++G+G   ++  il++++  +l+ ++ e++++
   EEA22051.1 41 KLIIVGAGIGGIAASILISNKVPNLEYVVYEKTDA 75
                 68888888888888887777766899999998765 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.075
  K_oxygenase 268 nykgvdaelieelyeelyeqkvkgeerlrllpnrevesaeaegkg.eveltlrneesgeeetlevdavvlATG 339
                   y gv+ ++  ++y+ + +  v  ++  +l+ +++v++a++  +  ++ +++ n  +g+++t+ +  vv A G
   EEA22051.1  84 RYPGVRCDVPSHIYHVVEKYGV--KP--NLRLQHQVTRATWIDEIsQWSVEILNLITGKTFTEIAHFVVSAAG 152
                  5777888888888887766666..44..4555678888888775449***********************998 PP

  == domain 3  score: 12.8 bits;  conditional E-value: 2.1e-05
  K_oxygenase 117 eeveevepdeeeeeelltveskd.aegeeeelearnlvlgvG..tepkiPevlekle....gkervvHsseylerkeellakkriaVvGsGqSaaeif 207
                  ++v++ ++ +e +   ++ve  +  +g++ +  a  +v + G  + pk+P+  +        k +  H+++  ++   + ++kria++G G S+ +++
   EEA22051.1 113 HQVTRATWIDEIS--QWSVEILNlITGKTFTEIAHFVVSAAGrlNVPKMPDDKQIPGirteFKGHYRHTADWDTNY--DWKGKRIAIIGNGASGQQLL 206
                  5555555555443..3444444445677777777666666665556666665432112222346788888888877..89****************** PP

  K_oxygenase 208 edllrrqkkvelklvtrse 226
                   ++++++ +  ++ ++rs+
   EEA22051.1 207 SNMVKDAGH--VDHYVRSK 223
                  ***999874..44444443 PP

  == domain 4  score: -0.4 bits;  conditional E-value: 0.22
  K_oxygenase 327 etlevdavvlATGYr 341
                  ++ evda++ ATG++
   EEA22051.1 359 TVREVDAIIAATGFQ 373
                  6789*********97 PP

>> Mqo  Malate:quinone oxidoreductase (Mqo)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0    0.0021       4.8       3      41 ..      40      78 ..      38      85 .. 0.91
   2 ?    2.6   0.0     0.017        39     197     241 ..     108     153 ..      94     169 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0021
         Mqo  3 vdvvliGaGimsatlgvllkelepelsievlerldkvae 41
                v ++++GaGi   + ++l+++  p+l+  v+e+ d+v+ 
  EEA22051.1 40 VKLIIVGAGIGGIAASILISNKVPNLEYVVYEKTDAVGG 78
                5689*******************************9975 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.017
         Mqo 197 elklkhevkdlkreed.gkWkvkvkdlktgekkkvkakfvfiGaGG 241
                 +l+l+h+v++ +  ++  +W+v++ +l tg++ +  a+fv   aG 
  EEA22051.1 108 NLRLQHQVTRATWIDEiSQWSVEILNLITGKTFTEIAHFVVSAAGR 153
                 6888999998876554378*********************988885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (574 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       391  (0.0218082); expected 358.6 (0.02)
Passed bias filter:                      375  (0.0209158); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.63u 0.32s 00:00:00.95 Elapsed: 00:00:00.48
# Mc/sec: 3618.40
//
Query:       EEA22052.1  [L=581]
Description: amino acid permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   4.8e-112  375.0  42.5   5.9e-112  374.7  42.5    1.0  1  AA_permease    Amino acid permease
    1.4e-38  132.8  46.8    2.1e-38  132.2  46.8    1.2  1  AA_permease_2  Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  374.7  42.5  6.6e-116  5.9e-112       2     476 ..      85     547 ..      84     549 .. 0.98

  Alignments for each domain:
  == domain 1  score: 374.7 bits;  conditional E-value: 6.6e-116
  AA_permease   2 vlvialggviGtglfvglgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgpelGfviGlnylfswitvlaleltaasi 99 
                  v +i l g iGtglfvg+g + ++aGp+g+lla++++g+v+++vm+s++e+at+ p++g f ++a+rf+++++Gf+ +l+y +++ +++a e  a++ 
   EEA22052.1  85 VSMIGLCGGIGTGLFVGTGMAYAKAGPAGLLLAFIVVGIVLWCVMQSIAELATLLPSAGTFPHWATRFIDQAVGFSLALSYGYCYSIAIASEASASAV 182
                  789*********************************************************************************************** PP

  AA_permease 100 liqfwelvtdlpkawvtgavflvvlliinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkga.gfrflgdngsifknnlppgfakeeeg 196
                  ++++w   tdl+   v+++v lv++l+inl +vk+yg +e+i  +ik++++++++iv+i++ +gg+pn++  gfr+++d+g++ + n + g     +g
   EEA22052.1 183 VVSYW---TDLS-PTVVITVGLVLILAINLSNVKFYGDVEVISGSIKVLCFLGLVIVSIVITTGGGPNHQVtGFRYWHDPGAWTNYNGITG----PTG 272
                  *****...9999.9********************************************************************888888888....889 PP

  AA_permease 197 afknfisvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasa.aspfvifikesgvsvlaplin 293
                   f++f+s fv ++f+f G e v+i+a+E+ +P ksiPka  +vv+ri++fYvl++llig++v+  +++l++++ +a +sp vi+ike+g+ +l++++n
   EEA22052.1 273 HFLGFLSSFVNASFSFIGVETVVIAAAEAINPHKSIPKAAQRVVYRIGFFYVLGALLIGMIVSPENPNLTSGTGNAnSSPWVIAIKEAGIHALPSVVN 370
                  9************************************************************************9999********************* PP

  AA_permease 294 aviltaalssansslysasRvlyslakdglaPkvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliilsylrfR 391
                  a+il++a+s++ns+  +asR++ ++  d+l+P v+++v+++gvP++a++  ++++ +a+l  +   +  ++f++ll++s++ gli w   +++y+rf 
   EEA22052.1 371 ACILVSAWSAGNSYCWVASRIIVAMTTDRLLPQVFGRVTRKGVPYVAVITAWLFGPFAYLSLGTGGS-SEAFTWLLNLSTVPGLIAWATLSFCYIRFY 467
                  ***********************************************************99999888.9***************************** PP

  AA_permease 392 kalkyqgrsieelgfkaallplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfliilvgvklhvknkrpq 476
                   alk+qg+s + l+ k++++p+ ++++++  +ii+l++++  +l+     ++w+++ f+a+y+++++f++ ++++kl  ++k+++
   EEA22052.1 468 AALKAQGISRDTLPWKSHFQPYAAWVGFVGSTIIVLVAGFPVFLK-----GNWSTSRFLASYIGIPIFIVPIIVWKLVNRTKFAR 547
                  *********************************************.....******************************99875 PP

>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.2  46.8   2.4e-42   2.1e-38      11     417 ..      88     520 ..      84     550 .. 0.79

  Alignments for each domain:
  == domain 1  score: 132.2 bits;  conditional E-value: 2.4e-42
  AA_permease_2  11 igsv..igsgifvkn..laasggpalilwvwiavligslavllvyaElssalprsgGiyvytkaafgkkvaflsawfnwfayvpvlasilsvaasy 102
                    ig++  ig+g fv +  ++a++gpa +l  +i+v+i++++v+  +aEl+++lp+ g+  +++ +++   v+f  a ++ ++y++++as +s+ a  
     EEA22052.1  88 IGLCggIGTGLFVGTgmAYAKAGPAGLLLAFIVVGIVLWCVMQSIAELATLLPSAGTFPHWATRFIDQAVGFSLALSYGYCYSIAIASEASASAVV 183
                    566666899999999888888***************************************************************997666666665 PP

  AA_permease_2 103 llnalgpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfssl........stetdtffpngwpg. 189
                      +++  dl ++ ++t++     l+l+ +in+ ++k ++ + +i g +k+l +l ++i+  +it +gg +++         +++++  + ng +g 
     EEA22052.1 184 VSYWT--DLSPTVVITVG-----LVLILAINLSNVKFYGDVEVISGSIKVLCFLGLVIVSIVITTGGGPNHQVtgfrywhdPGAWT--NYNGITGp 270
                    56644..67676544444.....6777789********************988888887777777665555447777764433333..33344432 PP

  AA_permease_2 190 ......vllgllivlwsfdGfesaanvsee..vkkkdvpkaifigllivlvlyllvniaflgvvpddeianlsnlgsv....aalffeavggkvva 273
                          +l+++  + +sf+G+e+++  + e  +++k +pka+  ++  ++++y+l ++++ ++v++++ + +s++g++    + +  + +g  ++ 
     EEA22052.1 271 tghflgFLSSFVNASFSFIGVETVVIAAAEaiNPHKSIPKAAQRVVYRIGFFYVLGALLIGMIVSPENPNLTSGTGNAnsspWVIAIKEAGIHALP 366
                    2232234777788*****************87778*******************************999777776654444499999999*99*** PP

  AA_permease_2 274 iivvilialsllgaintavigssrvlealardgvlPrffakvnkfgspiraiiltaivslillllfllas..saaynfllsvsslgliisylllii 367
                    ++v+++i +s++ a+n+++  +sr++ a+ +d+ lP +f +v ++g p++a+i+ +++  + + l+l++   s+a+++ll++s+++ +i ++ l++
     EEA22052.1 367 SVVNACILVSAWSAGNSYCWVASRIIVAMTTDRLLPQVFGRVTRKGVPYVAVITAWLFGPFAY-LSLGTGgsSEAFTWLLNLSTVPGLIAWATLSF 461
                    **********************************************************96555.55544458************************ PP

  AA_permease_2 368 galilrkkrphl..kr...pgk....ilvaiigalfllfllvalffppkgpatqssliy 417
                    +++  +   + +   r   p+k    +  a++g++++++++ ++ fp     ++s++ +
     EEA22052.1 462 CYIRFYAALKAQgiSRdtlPWKshfqPYAAWVGFVGSTIIVLVAGFPVFLKGNWSTSRF 520
                    **988888776655446784444555456666666666666555555333333333322 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (581 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       605  (0.0337442); expected 358.6 (0.02)
Passed bias filter:                      287  (0.0160076); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.46
# Mc/sec: 3787.04
//
Query:       EEA22053.1  [L=323]
Description: aldo/keto reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.6e-53  181.9   0.0    1.8e-53  181.6   0.0    1.0  1  Aldo_ket_red  Aldo/keto reductase family


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  181.6   0.0     1e-57   1.8e-53       2     288 ..       9     315 ..       8     319 .. 0.93

  Alignments for each domain:
  == domain 1  score: 181.6 bits;  conditional E-value: 1e-57
                   EEEE-SSS-ST.......TS-HHHHHHHHHHHHHTT--EEE--TT-...TTTHHHHHHHHHHHH-TTTGGG-EEEEEE--SSSTTSSSS-HHHHHHH CS
  Aldo_ket_red   2 lglGtwqlgsk......eeiskeealellrraleaGinffDtAevY...gkgqseellGealkksrkkreeviiatKvdlrdaeiksglskenires 89 
                   l+lG++++g+       ++ ++e + +l ++++ +G++ +DtA+ Y    ++++e l+G alk++++++  + i+tK+    +  +  + +e i+ +
    EEA22053.1   9 LVLGLANVGDTskdpmaRYGTPEAVKQLFDAFFNRGYTSLDTARNYpphAPCTAEPLIGSALKSYNENKPPFTISTKI---LHRGEHPHAREKIESN 102
                   788999998888877855556666677788888*************9999****************************...999999999******* PP

                   HHHHHHHHT-S-EEEEEE-S--TTS-.HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHH....HHTTT--EEEEE-B-BTT-HHHHTTHHHHHHHT CS
  Aldo_ket_red  90 leeslkrLgtdyvDllllHrpdpslpsieevldaleelvkeGkiraiGvSnfsveqleka....kkkkkvkivavqveynllreleeegllelckkk 182
                   + esl  L++ +vD+ +lH+pd+s+p  ee+++a+++ + eGk r +G+Sn+s e +e++    ++k++vk+++ q +yn   + +e+ l+++++k+
    EEA22053.1 103 ITESLTALQLPQVDIEYLHEPDRSTP-FEETCEAMNKAYLEGKFRRFGLSNHSPEEIEEVvkicEEKGYVKPSVCQGHYNAIARAAEKDLVPVLRKY 198
                   **************************.********************************************************************** PP

                   T-EEEEBSTTGGGTTGTTTSS---SSSCCC-------..........TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTS.....TT-SEEEE-- CS
  Aldo_ket_red 183 gvpliaysplggGlltgkyqseedkedkeprkdlkrd..........ertsknldaaeelselakehgvslaqlalryalsq.....pavgivipga 264
                   g+++ aysp + G+++g+y++++++++     d   +           + +    a++++ e+a +hg+s  ++alr++ ++     + +  +++ga
    EEA22053.1 199 GIAFYAYSPAAAGMFSGNYKTKTEVGNR---YDT--TlpigqlytrwYIRPSVISAVDAAVEIASKHGISGHAAALRWVAYHsvldaKYGDAIVLGA 290
                   ************************9854...333..1346779999999999******************************999888999****** PP

                   SSHHHHHHHHGGGG-.---HHHHHH CS
  Aldo_ket_red 265 snieqlednldalel.klseeevae 288
                   s++eql++n+d +e  +l+ee+ ++
    EEA22053.1 291 SKVEQLQQNMDIVEAgPLPEEVAEA 315
                   *************999**9998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (323 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       484  (0.0269954); expected 358.6 (0.02)
Passed bias filter:                      470  (0.0262145); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2264.61
//
Query:       EEA22054.1  [L=449]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (449 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       383  (0.021362); expected 358.6 (0.02)
Passed bias filter:                      318  (0.0177366); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.53u 0.22s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 3147.49
//
Query:       EEA22055.1  [L=233]
Description: hypothetical protein PMAA_058350 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.6e-13   48.3   4.9    7.6e-13   48.3   4.9    1.6  2  DUF3716   Protein of unknown function (DUF3716)


Domain annotation for each model (and alignments):
>> DUF3716  Protein of unknown function (DUF3716)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.3   4.9   4.2e-17   7.6e-13       1      58 [.      53     110 ..      53     111 .. 0.92
   2 ?   -3.0   0.1      0.43   7.7e+03      27      28 ..     132     133 ..     116     144 .. 0.58

  Alignments for each domain:
  == domain 1  score: 48.3 bits;  conditional E-value: 4.2e-17
     DUF3716   1 AlliqltGeeape.pCtrCrrgkgpFeeCvvveasekakllkgaCanClygkqgskCsl 58 
                 A+ i+++G  a+  pC+rC++ kgpF++Cv++   ++  +++  CanC++ +++s+C  
  EEA22055.1  53 AAKIYTHGAVADLaPCSRCAEAKGPFQKCVIA-WDNTGYVSNANCANCYWFHKTSSCDR 110
                 7889*******6626*****************.99999*******************85 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.43
     DUF3716  27 eC 28 
                  C
  EEA22055.1 132 AC 133
                 33 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (233 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       762  (0.042501); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.23s 00:00:00.68 Elapsed: 00:00:00.39
# Mc/sec: 1805.39
//
Query:       EEA22056.1  [L=511]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (511 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       576  (0.0321267); expected 358.6 (0.02)
Passed bias filter:                      519  (0.0289475); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.55u 0.25s 00:00:00.80 Elapsed: 00:00:00.42
# Mc/sec: 3672.47
//
Query:       EEA22057.1  [L=311]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.8e-61  206.0   0.4      7e-61  205.8   0.4    1.1  1  NmrA             NmrA-like family
    3.4e-15   56.4   0.0      6e-15   55.6   0.0    1.4  1  NAD_binding_10   NAD(P)H-binding
    0.00011   22.5   0.4    0.00069   19.9   0.3    2.2  2  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma
    0.00097   18.2   0.0     0.0013   17.8   0.0    1.2  1  3Beta_HSD        3-beta hydroxysteroid dehydrogenase/isomeras
     0.0026   17.3   0.0     0.0037   16.7   0.0    1.3  1  Epimerase        NAD dependent epimerase/dehydratase family
  ------ inclusion threshold ------
      0.012   15.9   0.4       0.02   15.2   0.4    1.3  1  TrkA_N           TrkA-N domain


Domain annotation for each model (and alignments):
>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  205.8   0.4   2.3e-64     7e-61       2     233 .]       6     245 ..       5     245 .. 0.94

  Alignments for each domain:
  == domain 1  score: 205.8 bits;  conditional E-value: 2.3e-64
                 EESSTTSHHHHHHHHHHHH.....HT-EEEEEES-S-SHHHHHHHHSTTEEEES-TT-HHHHHHHHTT-SEEEE---GG......S-HHHHHHHHHHHH CS
        NmrA   2 lviGaTGrqGksvvrallk.....aghkvralvRdtkselakslkeaGvelvkgdlddkeslvealkgvdvvfsvtgfy......skeiedgkklvdAa 89 
                 +++GaTG+qG+sv++++++     +++++ra++Rdt++ +a++l+++G e+v+gdldd +s+++a+kg+++vf+vt++         e+++gk+++dAa
  EEA22057.1   6 TILGATGNQGGSVANYVVAdpvlsKEYSIRAVTRDTQKPAAQELAAKGIEVVQGDLDDIDSIKAAFKGAHTVFAVTTTIydeqlkAREVRQGKAIADAA 104
                 89**************999999999**************************************************998789999999************ PP

                 HHHS-SEEEEEE---GG.GT.SSS---TTTHHHHHHHHHHHHCTS-EEEEEE-EEGGG-BSSS-SS-BEEE-TTS.-EEEEESS-TTS-EE-HHHHHHH CS
        NmrA  90 keaGvkhfiySslgddndrsnaeepavphfdsKaeieeyvralgipytfvyagffmenflsllaqlkvgdtappedkvtllgpgnpkavlldaeeDiGa 188
                  eaGvk +i+S+l +   +s++++p+v+ fdsK+e+e+y+r+l i + f+++  fm+n+ +++ +  +++ +    +++    g++k   + ++ D+G+
  EEA22057.1 105 IEAGVKYLIWSTLSSPTLESKGKYPNVESFDSKYEVEQYIRNLPIKSAFFAPSSFMQNYNRFVLP--HHSGDGT-FSIINVVRGDTKLPHIETKGDTGK 200
                 *****************************************************************..3333333.355666677777888899****** PP

                 HHHHHHHHHHHHTTEEEEE-SEEE-HHHHHHHHHHHHTS-EEEEE CS
        NmrA 189 fvikilkdprklkgkriklagntlsgneivelfekkigktvkYtq 233
                 +v ++l +p+k++gk+++ +++ +s+++++e +++ +gktvkY+q
  EEA22057.1 201 YVGAVLAEPDKFEGKVLSASTDLYSYDDVAETLTRLTGKTVKYNQ 245
                 *******************************************86 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.6   0.0     2e-18     6e-15       1     147 [.       9     160 ..       9     184 .. 0.80

  Alignments for each domain:
  == domain 1  score: 55.6 bits;  conditional E-value: 2e-18
                     TTTSHHHHHHHHHHHHC-....T-EEEEEETTHHHC..HHHHCTTTCEEEE--TT-CCHHHHHHTT-SEEEES---TCC......HHHHHHHHHH CS
  NAD_binding_10   1 GAtGkvGrllvkellarg....ghevtalvRnpekl..aeleaeeglevvegdvtdvedlaealkgadaVvsalggggk......deegaknivd 83 
                     GAtG+ G  +++  +a+     +++++a++R+++k   +el a++g+evv+gd+ d +++++a+kga +V++ + +  +      + ++ k+i+d
      EEA22057.1   9 GATGNQGGSVANYVVADPvlskEYSIRAVTRDTQKPaaQEL-AAKGIEVVQGDLDDIDSIKAAFKGAHTVFAVTTTIYDeqlkarEVRQGKAIAD 102
                     99*****9999999999888889*********776511456.57**************************9999443332333335566****** PP

                     HHHHCT--EEEEEEETTTTSGCGCHHHHHHHHCCHHHHHHHHHHHHHHHHSSSEEEEEEE-CEE CS
  NAD_binding_10  84 aakeagvkRfvlvsaigvgdevpgefgewnkellkaylaakraaeellrasgldwTivrpggLt 147
                     aa eagvk +++ +    + e++g+ +++      + ++ k++ e+++r+  ++  +  p+ ++
      EEA22057.1 103 AAIEAGVKYLIWSTLSSPTLESKGKYPNV------ESFDSKYEVEQYIRNLPIKSAFFAPSSFM 160
                     **********9988777776777777665......66899999999999877776666666665 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   0.3   2.3e-07   0.00069       2     101 ..       6     116 ..       5     148 .. 0.75
   2 ?   -0.8   0.0      0.57   1.7e+03       7      48 ..     196     242 ..     195     252 .. 0.71

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 2.3e-07
                      EEE--.SHHHHHHHHHHHCTCCT-G..EEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHHHTTSSEEEE-SSGG...........G CS
  Sacchrp_dh_NADP   2 liiGa.GsvGqavaellarhfdvda..eitvadrskeklealaakalgvrfeaialdaenyeavLaallkegdlvvnlsppi...........s 81 
                       i+Ga G+ G +va ++++   +++   i  ++r+ +k   +a++++ + +e ++ d +++++ ++a+ k++  v  +++ i           +
       EEA22057.1   6 TILGAtGNQGGSVANYVVADPVLSKeySIRAVTRDTQK--PAAQELAAKGIEVVQGDLDDIDS-IKAAFKGAHTVFAVTTTIydeqlkarevrQ 96 
                      59*****************9998888899999999999..55556688889999*********.********8888888888567777777777 PP

                      HHHHHHHHHHHT-EEEESS- CS
  Sacchrp_dh_NADP  82 sldvlkaCietgvhyvdtsi 101
                      + ++++a+ie+gv y+  s 
       EEA22057.1  97 GKAIADAAIEAGVKYLIWST 116
                      77788888888888876444 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.57
                      SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHH.....TTTC CS
  Sacchrp_dh_NADP   7 GsvGqavaellarhfdvdaeitvadrskeklealaaka.....lgvr 48 
                      G +G+ v  +la+ +++++++  a+ ++ + + +a+++     + v+
       EEA22057.1 196 GDTGKYVGAVLAEPDKFEGKVLSASTDLYSYDDVAETLtrltgKTVK 242
                      67888888888888888889988888888888888877555443333 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   4.4e-07    0.0013       9     114 ..      18     115 ..       6     128 .. 0.76

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 4.4e-07
   3Beta_HSD   9 lGralvkeLvrleelkevrvlDlrespelleelskvnvkkviegDvtdkdkleealegvdvvihlaslvdvagkltedeimkvnvkGTrnvleacvkag 107
                 + +++v   v  +e   +r++  +++++  +el   +++ v++gD+ d d++++a +g++ v+ +      + +++++++    v+  + + +a+++ag
  EEA22057.1  18 VANYVVADPVLSKE-YSIRAVTRDTQKPAAQELAAKGIE-VVQGDLDDIDSIKAAFKGAHTVFAV------TTTIYDEQLKAREVRQGKAIADAAIEAG 108
                 44444554455554.678888877777777777766666.*******************999988......44566677777889999*********** PP

   3Beta_HSD 108 vrvlvYt 114
                 v++l++ 
  EEA22057.1 109 VKYLIWS 115
                 *****85 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   1.3e-06    0.0037       3     107 ..       7     109 ..       5     145 .. 0.76

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 1.3e-06
                 EETTTSHHHHHHHHHHHHCT.....SEEEEEES-STTTTCHHCHHC..EEEE--TT-HHHHHHHHHHHT-SEEEE--S---HHHHHHSHHHHHHHHTHH CS
   Epimerase   3 VtGatGfiGsalvkallekg.....yevigldrlssasntarledl..elveldltdrsalerlfkeeqpdavihlAavggvaassedpadfieknlqg 94 
                 ++GatG  G  +++++ +       y + +++r++++ + ++l+ +  e+v++dl d ++++++fk  ++++v+ +       ++ ++ +++  + ++ 
  EEA22057.1   7 ILGATGNQGGSVANYVVADPvlskeYSIRAVTRDTQKPAAQELAAKgiEVVQGDLDDIDSIKAAFK--GAHTVFAV-------TTTIYDEQLKAREVRQ 96 
                 7888888888888887666556655*********99999999999899******************..88888877.......4444445555555666 PP

                 HHHHHHHHHHHTC CS
   Epimerase  95 tlnlleaarkagv 107
                    +++aa +agv
  EEA22057.1  97 GKAIADAAIEAGV 109
                 6666666666666 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   0.4   6.6e-06      0.02       7      72 ..      12      86 ..       6     110 .. 0.70

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 6.6e-06
                SHHHHHHHHHHHHTT......EEEEEEESSHHH..HHHHHHTTSEEEES-TTSHHHHHHT..TGGGESEEEE-SSS CS
      TrkA_N  7 GrvGrslaeeLsegg......kdvvvidkdeer..veelreeglevvvgdatdeevLeea..giekadaviaatgd 72
                G+ G s+a+++ ++       + + ++ +d ++  ++el+++g+evv+gd  d + +++a  g+ ++ av +++ d
  EEA22057.1 12 GNQGGSVANYVVADPvlskeyS-IRAVTRDTQKpaAQELAAKGIEVVQGDLDDIDSIKAAfkGAHTVFAVTTTIYD 86
                5556666666555444555544.777777776666**********************9885444444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (311 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       507  (0.0282782); expected 358.6 (0.02)
Passed bias filter:                      428  (0.0238719); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2190.17
//
Query:       EEA22058.1  [L=299]
Description: hypothetical protein PMAA_058380 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        5.2    7.0   8.6       0.36   10.7   1.6    2.1  2  TMEM154   TMEM154 protein family


Domain annotation for each model (and alignments):
>> TMEM154  TMEM154 protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.8      0.04   7.2e+02      11      31 ..      38      58 ..      23      84 .. 0.60
   2 ?   10.7   1.6     2e-05      0.36      18      78 ..     237     299 .]     224     299 .] 0.73

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 0.04
     TMEM154 11 aletatleeesadatsaaste 31
                +l+t  + + s+++++++st 
  EEA22058.1 38 SLSTSSVLTISSTSSLPTSTS 58
                444555555555555555552 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 2e-05
     TMEM154  18 eeesadatsaasteseslk..qeeakeslssaelsnesdqlelvlmiiiPlvllillllvvii 78 
                 +  s+ +++a  t ++s +  ++  +  +ss+ +   s+  +l l++  Pl ll llll+vi+
  EEA22058.1 237 SVASTALSIASKTVDSSAPvtTTAFRTVASSTSTTTSSSAASLQLLYSQPLRLLQLLLLLVIV 299
                 44566666777777777776244445566778888888889999***************9997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (299 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       656  (0.0365888); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 2050.87
//
Query:       EEA22059.1  [L=284]
Description: hypothetical protein PMAA_058390 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.1e-07   29.1   0.0     0.0002   21.5   0.0    2.9  3  BTB       BTB/POZ domain


Domain annotation for each model (and alignments):
>> BTB  BTB/POZ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.0   1.1e-08    0.0002      14      86 ..      17      89 ..      13     105 .. 0.86
   2 ?   -0.9   0.0      0.11   1.9e+03      25      40 ..     118     133 ..     115     147 .. 0.82
   3 !    3.8   0.0    0.0037        67      59      79 ..     216     236 ..     209     259 .. 0.82

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 1.1e-08
                EEEETT.TEEEEE-HHHHHHH-HHHHHHHTSTTTTTCCCEEEEETTSGHHHHHHHHHHHHHSEEEC-CGGGHHH CS
         BTB 14 tlvvgd.gkefkahkavLaarSpyFkalftskeieessvseielddvepeafealLefiYtgeleitseenlee 86
                t++vg  ++ +  h av+   S  +++l++++++ es++++ +l+dve+++f  + ef+Ytg+  ++ +++ +e
  EEA22059.1 17 TFLVGHdKTPLTIHTAVVENLSAPLSSLMNNGSMLESHTKTCTLEDVEASTFIGFCEFLYTGQYVTP-TKEGDE 89
                5666665788999*******************99****************************99887.555555 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.11
                 E-HHHHHHH-HHHHHH CS
         BTB  25 ahkavLaarSpyFkal 40 
                  hk  La rS++ ++l
  EEA22059.1 118 KHKNKLANRSSFYRNL 133
                 59999******99887 PP

  == domain 3  score: 3.8 bits;  conditional E-value: 0.0037
                 SGHHHHHHHHHHHHHSEEEC- CS
         BTB  59 vepeafealLefiYtgeleit 79 
                  +p+ + +lL+f+Yt + + +
  EEA22059.1 216 TNPKMILELLDFVYTNTGRAE 236
                 6889999********998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (284 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       372  (0.0207485); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 2088.39
//
Query:       EEA22060.1  [L=106]
Description: hypothetical protein PMAA_058400 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.11   12.7   0.0       0.12   12.5   0.0    1.1  1  CRIM      SAPK-interacting protein 1 (Sin1), middle CRIM doma


Domain annotation for each model (and alignments):
>> CRIM  SAPK-interacting protein 1 (Sin1), middle CRIM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   6.9e-06      0.12      21      85 ..      12      72 ..       5      93 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 6.9e-06
                CCGCCTTTT.-T-EEECCE-TT-SSTTS.---CCC-SSSCTCCCCCCCCCCCHCHT-SS-SS... CS
        CRIM 21 eyaalsgkgessslklkiyvpfskkpsvkplevkvrkdatvaevIGlaLykyveekrepeldeel 85
                ++++l g++ +++l+++  v   k+ s  pl v   +++ v  +IG++ y y+    +p+ + + 
  EEA22060.1 12 HFTFLVGEK-KTPLTIHPAVV--KTLS-APLGVATLEEVDVDTFIGFCEYVYTGAYMTPKCKYDA 72
                577777774.35555554444..5666.59999999***********************999654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (106 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       450  (0.025099); expected 358.6 (0.02)
Passed bias filter:                      254  (0.014167); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.37u 0.24s 00:00:00.61 Elapsed: 00:00:00.39
# Mc/sec: 817.97
//
Query:       EEA22061.1  [L=96]
Description: hypothetical protein PMAA_058410 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.075   12.6   0.1        0.4   10.3   0.0    2.0  2  TEP1_N    TEP1 N-terminal domain


Domain annotation for each model (and alignments):
>> TEP1_N  TEP1 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0     0.059     1e+03       8      14 ..       2       8 ..       1       9 [. 0.88
   2 ?   10.3   0.0   2.2e-05       0.4      14      26 ..      23      35 ..      19      36 .. 0.91

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.059
      TEP1_N  8 vSaHpDI 14
                vS++p+I
  EEA22061.1  2 VSVNPNI 8 
                8****99 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 2.2e-05
      TEP1_N 14 ILSLENRCLatLp 26
                ILSL  +CL+ L+
  EEA22061.1 23 ILSLQRQCLSKLH 35
                9*********996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (96 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       317  (0.0176809); expected 358.6 (0.02)
Passed bias filter:                      276  (0.0153941); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.33u 0.23s 00:00:00.56 Elapsed: 00:00:00.35
# Mc/sec: 816.99
//
Query:       EEA22062.1  [L=389]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.1e-14   53.0   0.7    8.2e-14   52.6   0.7    1.2  1  Metallophos  Calcineurin-like phosphoesterase


Domain annotation for each model (and alignments):
>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.6   0.7   4.6e-18   8.2e-14       2     203 ..      35     300 ..      34     301 .. 0.69

  Alignments for each domain:
  == domain 1  score: 52.6 bits;  conditional E-value: 4.6e-18
                  EEEEEESBTB......TTCCTHHHHHHHHHHHHHHHTTESEEEEESTSSSSS....HHHHHHHHH.HHHHHHHTSEEEEEC-TTS.........CHHH CS
  Metallophos   2 rilvigDlHl......algggqlddllkllddllreekpdlvllaGDlvdrg....dlekellel.laalvkypipvylllGNHe.........gfee 79 
                   i +++DlH+      ++g+ q  +  ++++ +l++e p lv+l+GDl+ +       ++ +l++ +a+lv ++  ++++ GNH+          f  
   EEA22062.1  35 QISIFSDLHYgeaedlDWGPQQDINSTRVMNSILDNESPQLVVLNGDLITGEntfkANSSHYLDQiVAPLVGRNLYWACTYGNHDsqfnlsrrdIF-- 130
                  56799**********************************************98999555558888799999999999********65544433311.. PP

                  HHHHHHHHHHHH.....HHHHEHH...HCEEETSEEEEEETTE....EEEEEEESECEEETHHHHHHHHHHHSCHHHHCC....HHHHHH.....HHH CS
  Metallophos  80 ellnkygylgif.....sepwrsd...aevfnnlplaslgsgs....lkvlllhGgspellvsldklgslnleleapepg....dewlkd.....lek 156
                    + +y++          +p+ ++   ++++  +++a+  +++    l ++   Gg     ++++++++     ++++       +w+ +     ++ 
   EEA22062.1 131 TREKRYPN---SltqsmVPPFSYEsgvSNYYLPVYSADKKDKTpkviLWFFDSRGG-----YEFQSVDKNGNGIPIDDFVdqsvVDWFTKtrdhlNKV 220
                  11111111...111122333333232333333333333222225565555555555.....4444444444444444433666777777788888888 PP

                  HTTCSEEEEEESSESS................................CSSSCSCCHHHHH.HHHHHTTESEEEEESSSS CS
  Metallophos 157 rekadwvivlgHsply................................rgsgylfgdeale.dllkkygvdlvisGHtHv 203
                   +k+ + ++++H+p++                                 +  y+  d+ ++  l +  g+ + isGH+H 
   EEA22062.1 221 HRKTIPSLAFFHIPVTamlafqetpgpkshtepginddvplagqgpsdGSFNYTGKDKPFMkALVETEGLIATISGHDHG 300
                  99*********************9999999999999999998888777555555555555535599999**********5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (389 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       343  (0.019131); expected 358.6 (0.02)
Passed bias filter:                      314  (0.0175135); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2889.01
//
Query:       EEA22063.1  [L=341]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.2e-06   25.5   0.0    1.5e-05   24.7   0.0    1.3  1  ADC       Acetoacetate decarboxylase (ADC)


Domain annotation for each model (and alignments):
>> ADC  Acetoacetate decarboxylase (ADC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.0   8.4e-10   1.5e-05      50     116 ..     129     196 ..     119     206 .. 0.89

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 8.4e-10
                 EEEEEEEEEECTTTCEEEEEEE..EEEEE.ETTEEEEEEEEEEESSHHHHHHHHHHTT--EEE-EEEEEE CS
         ADC  50 avyfaeypdssfgggqYneagi..vvpvr.yggkegayilvlwvdkeaalaaGRElwGfPKklAditltr 116
                 a+ +++y ds++g  +Y e+++  ++ v+ ++gk+ a i  ++v+ +a++  GR  w +PK  A++ ++ 
  EEA22063.1 129 ALLIIRYDDSDVG--PYDEVMVipGFFVNpHTGKRHARISNIYVSTDASVWNGRRNWNIPKHRARFVFEP 196
                 6789*********..****9986679**************************************999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (341 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       211  (0.0117686); expected 358.6 (0.02)
Passed bias filter:                      192  (0.0107089); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 2275.80
//
Query:       EEA22064.1  [L=896]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-28   99.3   0.0    2.7e-28   98.4   0.0    1.5  1  SLATT_fungal  SMODS and SLOG-associating 2TM effector domain
    1.2e-09   38.2   6.5    1.9e-09   37.5   6.5    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.078   12.9   0.1       0.18   11.7   0.1    1.6  1  S1-like       S1-like
        9.3    6.9  15.3       0.86   10.2   9.3    2.3  2  Pex14_N       Peroxisomal membrane anchor protein (Pex14p) co


Domain annotation for each model (and alignments):
>> SLATT_fungal  SMODS and SLOG-associating 2TM effector domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.4   0.0     6e-32   2.7e-28       2     120 .]     739     861 ..     738     861 .. 0.91

  Alignments for each domain:
  == domain 1  score: 98.4 bits;  conditional E-value: 6e-32
  SLATT_fungal   2 avkeerkaarkarltslalnlaiglQvllgAlltaLgalssgrtqvaitvLGalnTviAglLArlrgsgePersrkrrkdlekvireiea..felda 96 
                   +++++r++++++r ++ ++ +++++Q+++gA+ltaLg+l+s++  ++it+LGalnTviAglLA++ g+g+Per +k++  ++k++++ie+   +l+ 
    EEA22064.1 739 VINAKRAKTWQFRSLWCVVLVCHFAQIIIGAALTALGPLASDH-GIIITILGALNTVIAGLLALVSGQGLPERIQKDEIGYRKIQDWIEEteSLLSV 834
                   678999***********************************99.**********************************************9988999 PP

  SLATT_fungal  97 geasldvr...eeieelrrryeealan 120
                   g+ + +++     +ee++++y++a+ n
    EEA22064.1 835 GIIGRNRKevgLLVEEAFKKYNAAKSN 861
                   966655442335599*******99876 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.5   6.5   4.3e-13   1.9e-09       2      35 ..      13      45 ..      12      50 .. 0.88

  Alignments for each domain:
  == domain 1  score: 37.5 bits;  conditional E-value: 4.3e-13
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCT CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfyse 35
                aCd+Cr++K+KCd++ P C  C++ +++C + s 
  EEA22064.1 13 ACDPCRSRKRKCDGHLP-CETCVQFEYDCYYASA 45
                9****************.***********96555 PP

>> S1-like  S1-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.1   4.1e-05      0.18      10      26 ..     172     188 ..     170     204 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 4.1e-05
     S1-like  10 klqdtfGfvDeevfFqr 26 
                 k+   +Gf+D +vfF++
  EEA22064.1 172 KVAYAYGFIDSDVFFHH 188
                 66778**********97 PP

>> Pex14_N  Peroxisomal membrane anchor protein (Pex14p) conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   9.3   0.00019      0.86      57     143 ..     617     715 ..     583     722 .. 0.45
   2 ?   -2.4   0.3       1.5   6.9e+03      40      61 ..     849     876 ..     848     894 .. 0.32

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00019
     Pex14_N  57 vaassaseqaqeesasssatpqpqaasqtsqsspspsppaqqqqqqy.....................rpPivtypefltkppkppppPlrtwrdllit 134
                 ++++++s+ +q++s++++ t++p++++++ q++p+p+ p++q++  +                       P + +p      +++  pP+ +  + li+
  EEA22064.1 617 KQSEPQSQPQQGNSSKKTDTTPPAQPQPQPQAPPQPP-PQPQPT--AsigppmdvkptgpdgasgataAAPAQAWP------APAGLPPRDDDDERLII 706
                 1111222222222222222222222222222222221.111111..123344455566666666666666666663......44456666665555555 PP

     Pex14_N 135 atalaglga 143
                    ++g+ +
  EEA22064.1 707 FRRAVGINY 715
                 555555555 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 1.5
     Pex14_N  40 eeaLkraereeease...sa...vaass 61 
                 eea+k+ + +++++e   ++    a+++
  EEA22064.1 849 EEAFKKYNAAKSNEEnnrPSayvNAPEE 876
                 5666663322222222221122111111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (896 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       733  (0.0408835); expected 358.6 (0.02)
Passed bias filter:                      446  (0.0248759); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.77u 0.30s 00:00:01.07 Elapsed: 00:00:00.49
# Mc/sec: 5533.52
//
Query:       EEA22065.1  [L=450]
Description: monocarboxylate permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.3e-26   90.7  42.1    8.3e-26   90.7  42.1    1.5  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.7  42.1   4.7e-30   8.3e-26       5     349 ..      70     399 ..      66     405 .. 0.79
   2 !   15.0  10.3   4.9e-07    0.0088      53     166 ..     316     435 ..     309     443 .. 0.79

  Alignments for each domain:
  == domain 1  score: 90.7 bits;  conditional E-value: 4.7e-30
       MFS_1   5 aflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdr.fGrrrvlllglllfalglllll.fa.sslw.lllvlrvlqGlga 99 
                 +f++++++++ + ++ ++++e+lg sps++g++ ++ +++ +++ ++ Gr +d  +  r ++++g++l +lg ++l+ f+   l+ ++l   v  Glga
  EEA22065.1  70 VFFNTIGMTNSYGVFEQYYTETLGHSPSTVGWIGGIQMFLIFFGGVFSGRATDAgY-FRHCFVAGVVLQVLG-ICLTsFCeDKLYaIFLCQAVCYGLGA 166
                 7999*************************************************955.777************.55555999999989999999****** PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllgglla..sslgWravfyilaivsllafv...lfllllpeepperkrkspkeeekgtgp 193
                 g++f+ g+++++ +f+k +r++a+g+++ag + G ++ p+++ +l+  s +g+ +++ ++a+++l+  +   +++  +  ++++ +             
  EEA22065.1 167 GLVFTPGLSVTSSYFAK-KRTLAVGIVAAGGATGGMVYPAVANVLLyhSDVGFAWTMRVMALIMLITHIpsmIGYRCYIPPRSTGPL------------ 252
                 *****************.*************************777578888***************88654544444444444444............ PP

       MFS_1 194 aplvpawkallkdpvlwillialllfffgfsglltllplylqevlgls.glllaglllallalvgailallagrlsdr.lgrrrrlllallllllaalg 290
                    v+ w+a++ + ++ ++ + +l+ f+g+++++++l ++++++ +ls + l++   + +l  +g+i++++   l++r +g  +++++  +++++  ++
  EEA22065.1 253 ---VE-WSAFREKLFVTFIAANSLS-FWGLYMAFFYLGTFARSTIHLSdS-LSL---VIVLNGAGVIGRMVPNILAQRfTGVTNMNIICNVICAIYIFC 342
                 ...45.8899988877645555555.55********************33.444...555555555669999999988677777777777888888888 PP

       MFS_1 291 lallavt.ssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfntagslgg 349
                 ++ +  t   +v++++  +++G +++++ ++++ +++d+    + gt +g + t+ s+ +
  EEA22065.1 343 WMAIDSTaGLYVWSVVYGLFAGAAQALFPTMATHQTTDMS---KIGTRTGMVFTIISFFC 399
                 8888777556666666556666666665555555555554...67777777776666554 PP

  == domain 2  score: 15.0 bits;  conditional E-value: 4.9e-07
       MFS_1  53 Grlsdrf.Grrrvlllglllfalglllllfasslw.lllvlrvlqGlgagalfpagaaliadwfpk.eergraigllsagfslGailgpllggllassl 148
                   l++rf G   + +++ ++ a+  +++++a+ ++  l+v  v+ Gl+aga+ ++  +++++ +++ ++ g  +g++ + +s+  +  p++ g+l++  
  EEA22065.1 316 NILAQRFtGVTNMNIICNVICAIY-IFCWMAIDSTaGLYVWSVVYGLFAGAAQALFPTMATHQTTDmSKIGTRTGMVFTIISFFCLTSPAIEGALIQME 413
                 57899985777799**********.777777666668*****************************99****************************555 PP

       MFS_1 149 g....Wravfyilaivsllafv 166
                 g       +f  ++++   +++
  EEA22065.1 414 GgdymAAQLFSGCTVLVGAGCL 435
                 5475533335555554444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (450 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       587  (0.0327403); expected 358.6 (0.02)
Passed bias filter:                      264  (0.0147247); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 3096.08
//
Query:       EEA22066.1  [L=342]
Description: NmrA-like family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.7e-32  111.1   0.0    8.9e-32  110.5   0.0    1.3  1  NmrA            NmrA-like family
    1.8e-10   41.0   0.0    2.4e-10   40.6   0.0    1.2  1  NAD_binding_10  NAD(P)H-binding


Domain annotation for each model (and alignments):
>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.5   0.0   9.9e-36   8.9e-32       2     231 ..       9     270 ..       8     272 .. 0.93

  Alignments for each domain:
  == domain 1  score: 110.5 bits;  conditional E-value: 9.9e-36
                 EESSTTSHHHHHHHHHHHH...HT-EEEEEES-S-SHHHHHHHHSTTEEEES-TT-HHHHHHHHTT-SEEEE---GG...................... CS
        NmrA   2 lviGaTGrqGksvvrallk...aghkvralvRdtkselakslkeaGvelvkgdlddkeslvealkgvdvvfsvtgfy...................... 75 
                 +++GaTG+qG+sv++++l+   + +k r ++R+++s ++ sl ++Gve+v gd dd +sl++a+k++ ++fsvt f+                      
  EEA22066.1   9 VILGATGNQGGSVISYFLSqpsSPYKLRGVTRNPSSSKSLSLIARGVEMVTGDFDDPSSLDAAFKDATAIFSVTDFWqffinpslrekaassgqkigil 107
                 799***************999999*************************************************************************** PP

                 ..S-HHHHHHHHHHHHHHHS.-SEEEEEE---GG.GT.SSS---TTTHHHHHHHHHHHHC....TS-EEEEEE-EEGGG-BSSS-SS-BEEE-TTS.-E CS
        NmrA  76 ..skeiedgkklvdAakeaG.vkhfiySslgddndrsnaeepavphfdsKaeieeyvral....gipytfvyagffmenflsllaqlkvgdtappedkv 167
                   ++e+++ k+++d+ ++    ++fiySsl++  + s +++ +++hf+ Ka  eey ++        +  +yag + en+   +  ++   +++++ ++
  EEA22066.1 108 srDQEVQQNKNIIDVTAKVEtLERFIYSSLPNTCKLSGGKYSHIYHFEGKAIAEEYGKSKypklWEKTNVFYAGYYLENYFDAAGGMFRPRLSKDKGTL 206
                 ***************999999*************************************9988533356689***************9999999999999 PP

                 EEE..ESS-TTS-EE.-HHHHHHHHHHHHHHHHHHHTTEEEEE-SEEE-HHHHHHHHHHHHTS-EEE CS
        NmrA 168 tll..gpgnpkavll.daeeDiGafvikilkdprklkgkriklagntlsgneivelfekkigktvkY 231
                 +l+  +p  ++a ++  + +D+G ++ ++l   r+  g+ +  a++ ls+ e ++++ ++++k+vk+
  EEA22066.1 207 ILPatAPLATSALPMySSIDDTGVIIDALL---RASPGHKVIGANKWLSLREFAQILAQVLEKNVKF 270
                 8863368899999999999***98877776...456899999***********************98 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.6   0.0   2.7e-14   2.4e-10       1     102 [.      12     141 ..      12     168 .. 0.81

  Alignments for each domain:
  == domain 1  score: 40.6 bits;  conditional E-value: 2.7e-14
                     TTTSHHHHHHHHHHHHC-..T-EEEEEETTHHHCHHHH.CTTTCEEEE--TT-CCHHHHHHTT-SEEEES-................--TCC... CS
  NAD_binding_10   1 GAtGkvGrllvkellarg..ghevtalvRnpeklaele.aeeglevvegdvtdvedlaealkgadaVvsal................ggggk... 73 
                     GAtG+ G  +++  l++    ++++ ++Rnp++ ++l+  + g+e+v+gd+ d+++l +a+k+a a++s +                ++g+k   
      EEA22066.1  12 GATGNQGGSVISYFLSQPssPYKLRGVTRNPSSSKSLSlIARGVEMVTGDFDDPSSLDAAFKDATAIFSVTdfwqffinpslrekaaSSGQKigi 106
                     9****************9999***********9998775459***********************************999988887522233567 PP

                     ...HHHH..HHHHHHHHHH.CT--EEEEEEETTTT CS
  NAD_binding_10  74 ...deeg..aknivdaake.agvkRfvlvsaigvg 102
                        d+e+   kni+d+  + +  +Rf++ s  ++ 
      EEA22066.1 107 lsrDQEVqqNKNIIDVTAKvETLERFIYSSLPNTC 141
                     666333366******97772558****99876665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       365  (0.0203581); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.48
# Mc/sec: 2161.76
//
Query:       EEA22067.1  [L=324]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-06   28.7   8.3      1e-06   28.7   8.3    1.6  2  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain
     0.0083   16.1   0.0      0.019   14.9   0.0    1.6  1  Swi3      Replication Fork Protection Component Swi3


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.7   8.3   1.2e-10     1e-06       1      35 [.       6      39 ..       6      42 .. 0.94
   2 ?   -2.9   0.1      0.87   7.8e+03      21      32 ..      60      70 ..      58      76 .. 0.61

  Alignments for each domain:
  == domain 1  score: 28.7 bits;  conditional E-value: 1.2e-10
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCT CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfyse 35
                +aC +C   K+KC  + P+C +C +++l Ct y+ 
  EEA22067.1  6 KACRQCTVSKRKCIVQLPKCERCSQKGLACT-YDL 39
                59*****************************.875 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.87
                HHHHHCTHHHCC CS
     Zn_clus 21 snCkklnleCtf 32
                snC + ++ C+f
  EEA22067.1 60 SNCDTPGY-CVF 70
                77777664.655 PP

>> Swi3  Replication Fork Protection Component Swi3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   2.1e-06     0.019      23      54 ..     176     207 ..     163     210 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 2.1e-06
        Swi3  23 lkfkgkgheaedlkkllqfyqlWahrLfPkak 54 
                 + f+ +g e  dl +l++++  W++ LfP a+
  EEA22067.1 176 FIFSPNGPEQFDLVQLMNTLSAWTQALFPSAQ 207
                 56777999999******************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (324 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       631  (0.0351944); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.43
# Mc/sec: 2288.25
//
Query:       EEA22068.1  [L=343]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.4e-05   23.7   1.3      0.033   14.5   0.0    2.4  2  DUF4133     Domain of unknown function (DUF4133)
    0.00054   19.4   4.5     0.0063   15.9   0.2    2.2  2  DUF4191     Domain of unknown function (DUF4191)
  ------ inclusion threshold ------
      0.021   14.4   0.0      0.032   13.7   0.0    1.2  1  Tfb4        Transcription factor Tfb4
      0.029   14.1   0.1       0.18   11.6   0.0    2.1  2  TMEM132D_C  Mature oligodendrocyte transmembrane protein, TME
       0.22   10.2   2.5        4.5    5.9   0.1    2.1  2  DUF2207     Predicted membrane protein (DUF2207)


Domain annotation for each model (and alignments):
>> DUF4133  Domain of unknown function (DUF4133)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.0   9.2e-06     0.033      17      73 ..     138     194 ..     136     202 .. 0.92
   2 !    7.7   0.3    0.0012       4.3      25      74 ..     246     297 ..     237     308 .. 0.69

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 9.2e-06
     DUF4133  17 qylfilagglvallllvvilyiiGvsqliclalivvagsllvvlvfrlnkkyGehGl 73 
                  ++f+ + +++  ++lv++lyi  +  + cl ++++a  + v+++ r  +  G  G+
  EEA22068.1 138 PHIFYWLSAILSPVVLVFFLYIREWWGVFCLLVLMFARLCNVFVIRRRTRDVGWKGA 194
                 689******************************************999999998886 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0012
     DUF4133  25 glvallllvvilyiiGvsqliclalivvagsllvv..lvfrlnkkyGehGlm 74 
                  +++ + + ++  i   +q+i+l++ v++++ll++   + r ++ yG++  +
  EEA22068.1 246 TVLVYVNTALVSNIRTFNQIIILIMFVLSAALLFLanITTRAMHMYGRRIQV 297
                 3444444457888889999999988888777665422688999****97554 PP

>> DUF4191  Domain of unknown function (DUF4191)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.2   1.7e-06    0.0063      14     105 ..     128     219 ..     125     225 .. 0.77
   2 !    4.8   0.8    0.0042        15      30      75 ..     244     289 ..     232     301 .. 0.57

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 1.7e-06
     DUF4191  14 vfkltrkedkkllwlllaaflvvvvvfvvlglllgslilllilgillgllvalivltrraekaayaqiegqpGaaaavlenlrr.gwrvep.av 105
                 +f+ ++k+    +++ l a+l +vv+++ l +  +++ ++++l ++++ l+ ++v+ rr++ + ++ +  +pG  +  l  l++  w   + av
  EEA22068.1 128 AFSWKAKDLAPHIFYWLSAILSPVVLVFFLYIR-EWWGVFCLLVLMFARLCNVFVIRRRTRDVGWKGAS-EPGVRGDLLILLSGdCWVRMQgAV 219
                 566666666667788899999999998888887.5788999*********************9998765.688888888777774454433355 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.0042
     DUF4191  30 laaflvvvvvfvvlglllgslilllilgillgllvalivltrraek 75 
                 la++lv v  ++v  + + ++i++li+ +l ++l++l  +t ra +
  EEA22068.1 244 LATVLVYVNTALVSNIRTFNQIIILIMFVLSAALLFLANITTRAMH 289
                 2333333333333333334677777777777777777777777654 PP

>> Tfb4  Transcription factor Tfb4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0     9e-06     0.032      10     102 ..     226     321 ..     224     327 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 9e-06
        Tfb4  10 tnpkawaeleekltlsevlasllvflNahLaln..aaNkvaviashsqkakflYpseek.ekeaskkkdvelskssknkyrefrlvdelvveelke 102
                 t+ k+w e + +    ++la +lv++N+ L+ n  + N++ ++ +   +a+ l+  + + ++ +   ++++++ + k+ yr+  ++del++e+ ++
  EEA22068.1 226 TSGKWWRERTMAEDCLTALATVLVYVNTALVSNirTFNQIIILIMFVLSAALLFLANITtRAMHMYGRRIQVKGKPKKYYRRRDMADELIAESGRK 321
                 5678999999999999**************9873357*****99999999999977665266677788999999999*************998765 PP

>> TMEM132D_C  Mature oligodendrocyte transmembrane protein, TMEM132D, C-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0     5e-05      0.18      40      70 ..     164     194 ..     162     213 .. 0.87
   2 ?   -0.7   0.0      0.34   1.2e+03      45      70 ..     275     301 ..     266     323 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 5e-05
  TMEM132D_C  40 gvfClAilvflincvvyalkfrrkkvpvegq 70 
                 gvfCl +l+f   c v++++ r ++v  +g 
  EEA22068.1 164 GVFCLLVLMFARLCNVFVIRRRTRDVGWKGA 194
                 8***********************9998884 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.34
  TMEM132D_C  45 Ailvflincvvyalkfrrkkvpveg.q 70 
                 A l fl n ++ a+ +  ++++v+g +
  EEA22068.1 275 AALLFLANITTRAMHMYGRRIQVKGkP 301
                 667899999999998888888888743 PP

>> DUF2207  Predicted membrane protein (DUF2207)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.4    0.0039        14     379     439 ..     127     187 ..     111     194 .. 0.67
   2 ?    5.9   0.1    0.0013       4.5     210     250 ..     265     305 ..     214     313 .. 0.52

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.0039
     DUF2207 379 klkklsalglgliilglilillallllvlllvfllilllillliaiivlllfsrllgrrte 439
                 k++++ a  l+  i++++ ++l+ ++lv++l++  ++++++ll+++++ l+   +++rrt+
  EEA22068.1 127 KAFSWKAKDLAPHIFYWLSAILSPVVLVFFLYIREWWGVFCLLVLMFARLCNVFVIRRRTR 187
                 5667777777777777777777777777775555555555555555555555556666665 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0013
     DUF2207 210 illilllilllllllllliklllwkkygrepkvkevdpeYe 250
                 i++++  +l ++ll+l+ i++++ + ygr+ +vk +  +Y+
  EEA22068.1 265 IIILIMFVLSAALLFLANITTRAMHMYGRRIQVKGKPKKYY 305
                 22222222222222223333344444666666666555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (343 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       731  (0.0407719); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 2436.67
//
Query:       EEA22069.1  [L=876]
Description: Ankyrin and HET domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.1e-36  124.5   4.7    7.9e-36  123.6   4.0    1.9  2  HET       Heterokaryon incompatibility protein (HET)


Domain annotation for each model (and alignments):
>> HET  Heterokaryon incompatibility protein (HET)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.6   4.0   4.4e-40   7.9e-36       1     146 []      54     195 ..      54     195 .. 0.89
   2 ?   -2.9   0.0      0.44   7.9e+03      70      92 ..     215     236 ..     214     276 .. 0.58

  Alignments for each domain:
  == domain 1  score: 123.6 bits;  conditional E-value: 4.4e-40
         HET   1 YeaLSYvWgdskekeeievng....klleltenledalqvlrk.lgerylWiDaiCInQdddkekskqvqlmadIYsnAelvivalgsesedsgllale 94 
                 Y +LSY+Wgd++ +e+i++ +     ++ ++ nl++al++lr+ ++ rylW+DaiCI+Qdd++eks+qv++m++I++n+++v+v++g+e++ds  +a++
  EEA22069.1  54 YDTLSYTWGDQDPTEHIKIIHanqqYRIPIRPNLHQALSHLRShREDRYLWVDAICIHQDDEREKSSQVRMMSQIFNNSSCVCVWIGPEKDDS-RRAID 151
                 99**********999998866676788999************86888*******************************************999.99999 PP

         HET  95 alralkkekleekeielkksaekkkellekeeraieellespwfkRvWvlQE 146
                 ++++    +  + +         ++ ++++e+ a+++l+++pwf+R W++QE
  EEA22069.1 152 FIKSRLVHDDAD-QLL-------ENFEYRHEWLALSKLMRRPWFSRRWIIQE 195
                 988766666655.222.......235799**********************9 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.44
         HET  70 IYsnAelvivalgsesedsglla 92 
                 I+s+A + +++ +s+  ++ l++
  EEA22069.1 215 IFSEAVMLFTWGQSKVYST-LRT 236
                 6677777776666665444.333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (876 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       397  (0.0221429); expected 358.6 (0.02)
Passed bias filter:                      316  (0.0176251); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.44
# Mc/sec: 5964.99
//
Query:       EEA22070.1  [L=473]
Description: GPI-anchored cell wall beta-1,3-endoglucanase EglC [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.8e-07   30.0   1.1    5.3e-07   29.5   1.1    1.3  1  Glyco_hydro_17  Glycosyl hydrolases family 17


Domain annotation for each model (and alignments):
>> Glyco_hydro_17  Glycosyl hydrolases family 17
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.5   1.1   2.9e-11   5.3e-07      59     292 ..      83     295 ..      26     315 .. 0.68

  Alignments for each domain:
  == domain 1  score: 29.5 bits;  conditional E-value: 2.9e-11
  Glyco_hydro_17  59 laelesnqskaavWvq.dnvrpaaekvkikyiavgneispstsaakavflvpamanirna...lt.aaglsnkikvstalaldildssyppsqst 148
                     +a   + +  ++ W   d  ++++e+ k +  ++g e+ +  +++     v+++ ++rn+   ++ +ag+    k+  +++ +i+         +
      EEA22070.1  83 AAIKTNTTLLLGLWASgDTFNNEVEALKTAISTYGSELANLIVGI----SVGSEDLYRNSdmgIKaKAGIG---KNPEDIVNGIKAVRATIAGTA 170
                     333345566788998725568899**************9999988....99******99732222134554...566677777777763333334 PP

  Glyco_hydro_17 149 freevkpvvdpivvflagtnspllvnvyPYfvysndpsnvsLdyalfqkqslvndnglayrnlfDaildavyaaqekkGgtdielvvsEtGWPsd 243
                     ++++    vd +  + + +n+ ++++v+ ++    d       y +fq+   +    +  ++lf   ldav  + ++  g++  l+v EtGWP  
      EEA22070.1 171 ISHAPIGHVDTWTAWYNTSNKDVIDAVD-WLG--LD------AYPYFQNTDSND--VTSGKSLF---LDAVNKINSASNGKS--LWVTETGWPVS 249
                     44444477********************.333..33......3999*9887773..55668898...889999988877775..8********** PP

  Glyco_hydro_17 244 GstgaslenaatyveNlikkvkeGtpskpgkgietyvfalFdEnqKpee 292
                     G+   + + a+++ve ++  + e  +      ++ty + l d ++  ++
      EEA22070.1 250 GK---QENLAVASVEAAKTYWDEVGCGLLFDKVNTYWYILQDAAKSTPS 295
                     **...33468888888888888888888888888888877666554444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (473 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       727  (0.0405488); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.32s 00:00:00.92 Elapsed: 00:00:00.48
# Mc/sec: 2963.42
//
Query:       EEA22071.1  [L=311]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    8.1e-63  212.1   0.0    9.8e-63  211.8   0.0    1.1  1  DUF3431    Protein of unknown function (DUF3431)
  ------ inclusion threshold ------
       0.12   12.4   0.0       0.31   11.0   0.0    1.7  2  TetR_C_14  MftR C-terminal domain


Domain annotation for each model (and alignments):
>> DUF3431  Protein of unknown function (DUF3431)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  211.8   0.0   1.1e-66   9.8e-63       1     215 []      68     292 ..      68     292 .. 0.89

  Alignments for each domain:
  == domain 1  score: 211.8 bits;  conditional E-value: 1.1e-66
     DUF3431   1 lVvaklkeedtsWvee..elpdlqtaiYvvd.dpsaeltvp.ankGreamaYltyiidnYdsLpdvvvFvhahraawhndaldydnaallrrlrleavq 95 
                 +Vvak++ e+++W+    e   +++++Y +d +p++ l vp ++ G+ea aYltyi++nYd+Lp +++Fvha++++whn+ +  +++++lr lr+e v 
  EEA22071.1  68 IVVAKTRGENIDWLLPfcEEYICKPYVYSMDpEPEEGLLVPnTTMGHEAAAYLTYIVNNYDKLPPYTIFVHANDEQWHNELFGPKTTTALRFLRYESVD 166
                 8***************55444589999***966688899985679***********************************99***************** PP

     DUF3431  96 eeGYvnlrckwepgCpaelkplekeeeekkeeealaeafaelf......eeeevpevvaapcCaqFavsrerirkrpreeYvrlrqwlleteldd.els 187
                 ++G+vnlrc+  pgCp++l p+++e   ++e +++++ f el+      + ++vp+vv++ cC+qF+v+r+ri++rpre+Y+r+ +w  +t+ +d + +
  EEA22071.1 167 ANGFVNLRCTGIPGCPNTLIPVHRE-PVDDEYAYVSDKFFELYsyllqvPMDQVPQVVGHLCCGQFVVARDRILARPREDYERILTWAATTDFTDsYGI 264
                 ******************9999744.44555556666666666555577777****************************************6551679 PP

     DUF3431 188 GrvleylWhilFgkeavaCpdeeecycd 215
                 G+++e++Wh+lFg+e+v+Cp+ e+c cd
  EEA22071.1 265 GWTIEKIWHVLFGREPVDCPRLEQCRCD 292
                 ***************************7 PP

>> TetR_C_14  MftR C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0      0.68   6.1e+03      24      53 ..      40      69 ..      23      73 .. 0.76
   2 ?   11.0   0.0   3.5e-05      0.31      65     103 ..     215     253 ..     211     256 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 0.68
                HHHHHHHHHHHSHHHHHHHHHHHHHHHHHH CS
   TetR_C_14 24 ehrrRmrLiltvPaLqAhstlryaawrevv 53
                +h +R  L+ t+P   ++s + + + r++v
  EEA22071.1 40 NHVARDMLLPTNPHFMSQSRNWTIEDRNIV 69
                678888888899988888877666666655 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 3.5e-05
                 TTSHHHHHHHHHHHHHHHHHHHHHHH-TTS-HHHHHHHH CS
   TetR_C_14  65 addlvprtvaaavlaaalaayeqwladedadlaelLdea 103
                 + d vp++v++++ +  ++a ++ la++ +d++ +L+ a
  EEA22071.1 215 PMDQVPQVVGHLCCGQFVVARDRILARPREDYERILTWA 253
                 6799****************************9999755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (311 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       425  (0.0237046); expected 358.6 (0.02)
Passed bias filter:                      356  (0.0198561); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2161.42
//
Query:       EEA22072.1  [L=479]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.9e-22   78.0  24.3    1.3e-21   77.0  23.7    1.8  1  Acyl_transf_3    Acyltransferase family
  ------ inclusion threshold ------
      0.027   14.9   0.1       0.18   12.2   0.1    2.4  1  Caps_synth_CapC  Capsule biosynthesis CapC


Domain annotation for each model (and alignments):
>> Acyl_transf_3  Acyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.0  23.7   1.5e-25   1.3e-21       2     322 ..      35     396 ..      34     437 .. 0.81

  Alignments for each domain:
  == domain 1  score: 77.0 bits;  conditional E-value: 1.5e-25
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxxxxxxxx..........xxxxxxxxxxxxxxxxxx RF
  Acyl_transf_3   2 aylDllRgiAillVvflHaliayspdagrgspiqasqssqi.......aflggfgvplFFllSGffla..........amlyrrrglsklikrRil 80 
                    +++D+lRg+A +lVv+ H + a ++d +   +  +     +          g++gv++F +l+G+++a          + +    ++ k  +rR +
     EEA22072.1  35 KWIDGLRGFASVLVVATHLARAWDYDLFAPRSGPDVPPRLLqqlvlriPWQGRIGVTIFAFLTGYVCAlkpmkqaragDANGAFMTVAKSAFRRPP 130
                    79*******************9999998887777765555577799996669******************************************** PP

                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Acyl_transf_3  81 rlliplliwllliillialvaghiqanasanvtlfdet....................kglmfllfefpatghlWfLwalfvlylllplllrllrk 156
                    rl+ p  i +++ ++l +++a+      + ++t  ++                     ++++++ +   ++ h W L  l+ +++l+++   ++  
     EEA22072.1 131 RLVFPATIAMCISWTLAQFGAYTVGNRCDSSWTRDASPdlrdtlweefirlfqnflvaWTNTDYNVHMVYDEHQWALLPLLKCSMLIYIVSFATIL 226
                    **********************9999999999999888999******************************************************* PP

                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...... RF
  Acyl_transf_3 157 vrkshlllllilllllslvfirhelfgpatsvgllplpsvlallfflfGalladaddrdrnlsrglkislllsllllalillalfgqtdg...... 246
                     + +++ll+++ll+++++    +    +   ++         + ++l+ + + + ++  +++ + ++ +++++++l++++l+++ + +        
     EEA22072.1 227 CKYRWRLLICVLLIAYFHQDPKLDRETFQIQAL---------YGMILSDLSYEQRYKSFMQSETYRWPRRIIAWTLFVGGLVVCSYPGEHpewagw 313
                    *********************999966633222.........344444445555555555555577777777777777777777777766999999 PP

                    ......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Acyl_transf_3 247 ......gglvasvliqsaslllvslgimllllllfalpsrsafk...llrylgkiSygiYliHlpllmllqkllrdwglnlgevl 322
                            ++ + l + +   + ++g+ +++++ f+ ++ ++f+   +l ++gk S+++YliH+ ll ++  +++  ++   e++
     EEA22072.1 314 snrmfeWAPYLFPLGSNYGKRWTAVGMDMIIMSIFLTNWSKEFLsspVLLWFGKQSFAVYLIHGTLLRTVLVWMIYGITG--EPW 396
                    99988755555555555555566666666666666666666666888****************99999998888877322..222 PP

>> Caps_synth_CapC  Capsule biosynthesis CapC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.1     2e-05      0.18      39      88 ..     343     393 ..     336     406 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2e-05
  Caps_synth_CapC  39 tllialltylivrl.lsrflilyGrrrfvavlllgvlvklllelllllllp 88 
                      ++++ +lt +  ++  s +l+++G++ f++ l+ g+l++++l +++  +++
       EEA22072.1 343 IIMSIFLTNWSKEFlSSPVLLWFGKQSFAVYLIHGTLLRTVLVWMIYGITG 393
                      6667778888888844456779********************999877655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (479 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       472  (0.0263261); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.41
# Mc/sec: 3490.07
//
Query:       EEA22073.1  [L=235]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-10   42.0   1.3    3.9e-10   40.6   0.0    2.0  2  Pal1      Pal1 cell morphology protein
  ------ inclusion threshold ------
       0.21   12.0   3.1         14    6.2   3.1    2.2  2  DUF2681   Protein of unknown function (DUF2681)


Domain annotation for each model (and alignments):
>> Pal1  Pal1 cell morphology protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.3      0.13   1.2e+03      72      76 ..      51      55 ..       2      78 .. 0.47
   2 !   40.6   0.0   4.4e-14   3.9e-10       1      54 [.      80     130 ..      80     193 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.13
        Pal1 72 eddkd 76
                ++++d
  EEA22073.1 51 KQQQD 55
                11111 PP

  == domain 2  score: 40.6 bits;  conditional E-value: 4.4e-14
        Pal1   1 DtiDkLDvtglfgglfHHdGPfDAvtphrNknskaaPvlAfpkdgannslggag 54 
                 D+iD+LD   +   ++HH+GP+DAv p+rN  sk++P+ A  kd+ +++l++++
  EEA22073.1  80 DVIDQLDNVNFM--QYHHEGPYDAVYPERNVCSKRSPLEAV-KDSNEETLRATP 130
                 99******9997..8*************************6.899999998763 PP

>> DUF2681  Protein of unknown function (DUF2681)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   3.1    0.0016        14      39      83 ..      47      90 ..      27      92 .. 0.86
   2 ?    3.6   0.0    0.0098        88      58      81 ..     118     141 ..     114     144 .. 0.92

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0016
     DUF2681 39 kqqlkvekavaeaevknakvkqkneentrrlsrdsvddqLhqhgy 83
                 + +k+++ ++  + +    ++++    +r+++d v+dqL + ++
  EEA22073.1 47 RESIKQQQDIQRRKTQRTSNSKRHSHRRNRVNPD-VIDQLDNVNF 90
                577888999999999999999***********95.8999998876 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.0098
     DUF2681  58 vkqkneentrrlsrdsvddqLhqh 81 
                 vk  nee++r     +++d L+ h
  EEA22073.1 118 VKDSNEETLRATPMYKIIDSLQRH 141
                 8999******************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (235 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1260  (0.0702772); expected 358.6 (0.02)
Passed bias filter:                      548  (0.030565); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 1671.89
//
Query:       EEA22074.1  [L=295]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-85  286.0   0.1    2.5e-85  285.8   0.1    1.0  1  HVSL      Uncharacterised conserved protein


Domain annotation for each model (and alignments):
>> HVSL  Uncharacterised conserved protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  285.8   0.1   1.4e-89   2.5e-85       1     237 [.      37     290 ..      37     291 .. 0.97

  Alignments for each domain:
  == domain 1  score: 285.8 bits;  conditional E-value: 1.4e-89
        HVSL   1 PpLPssfhdlyastvrtsteddpslhqGrkRsiphveGnWpthvYlewkpseeekellsellkkleekl.eeevklhslltsdlgaplplHiSLSrplv 98 
                 P LP++fhdlyas+ r+s++ddp+lh+GrkR+iphveGnWpth+Ylew+p ++e ++l ++l+k+e++  + ++k+ sll+s+lg++lplH+SLSrp+v
  EEA22074.1  37 PALPTAFHDLYASSIRVSVRDDPNLHGGRKRVIPHVEGNWPTHIYLEWYPRRDELAVLADVLSKCEAESnHGTSKICSLLYSELGVQLPLHVSLSRPVV 135
                 89****************************************************************9998999************************** PP

        HVSL  99 lrthqkdsfldslkkelkssakrrFevsfsglkwvsndektRsFlvlrvkspendeLkklleavnkvleefglpply...................... 175
                 l+t+qk++f++++++++k+s++++F+v +++l+wvsn e+tR+Flv+r+++p++d+L++ll+++n++l+++g+pply                      
  EEA22074.1 136 LSTDQKQPFIEAFEHAIKASNTKPFTVVPDTLDWVSNTERTRWFLVIRLEKPKDDNLNRLLRISNRILDSYGQPPLYateigatnrllkhdktkppvae 234
                 ******************99999**************************************************************************** PP

        HVSL 176 ...kdeaFHiSiawslgepseeekeellselekaledaekeeelkqleikveevkvkiGnkvtsi 237
                    ++++FHiS+awsl+eps ee+++++s           ++e+ +lei++++vk+kiGn+v+s+
  EEA22074.1 235 vddYTNCFHISLAWSLTEPSLEEQQRVSSIA---------LDEMASLEINFSSVKAKIGNVVHSL 290
                 *******************888888776666.........577889*****************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (295 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       358  (0.0199677); expected 358.6 (0.02)
Passed bias filter:                      334  (0.018629); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 2060.38
//
Query:       EEA22075.1  [L=185]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-37  129.9  10.5    1.5e-37  129.7  10.5    1.0  1  DUF3807   Protein of unknown function (DUF3807)
  ------ inclusion threshold ------
      0.012   15.2   2.3      0.016   14.8   2.3    1.1  1  Med8      Mediator of RNA polymerase II transcription complex


Domain annotation for each model (and alignments):
>> DUF3807  Protein of unknown function (DUF3807)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  129.7  10.5   1.7e-41   1.5e-37       1     182 []      18     184 ..      18     184 .. 0.81

  Alignments for each domain:
  == domain 1  score: 129.7 bits;  conditional E-value: 1.7e-41
     DUF3807   1 DLqaFhakHFseastdhfesqfleeeeeaeeeeydeedDgLGYYpDGvKRTLTDeQIaiFRHSEieallRereleeeesekekkeeeeeeedkeaadke 99 
                 DLq+F+a+HF    t+ +      ++ +++eee +++dD+LGYY+DG+KRTLTDeQI+iFRHSEi+allRere+ +ee       e+ee++d ea+d  
  EEA22075.1  18 DLQKFQASHFFGITTSPAGPAQ--SDLVENEEESYHQDDDLGYYKDGTKRTLTDEQIEIFRHSEIHALLRERERLREE-------EAEEQSDVEARD-I 106
                 9**********66666555543..345678888899*************************************99988.......557888889999.5 PP

     DUF3807 100 ssqeseeqekkkkskkkskkkkkrakkakekkekkeekkidlrkrtwdkvdkglasldyddeeeeeqksaekaaqRrrisydD 182
                 +s ++++ + + +++++ ++ k+++ + +e++++k++k+++ + r ++   +++as+++ ++++   +s++ +++R+++sy D
  EEA22075.1 107 ESGKTSKVDGDIRKAADISALKRKSVEGSEDSSAKRAKDEEGTARPSEC--DTAASTQQPQQTA---SSRDINFGRKIVSYAD 184
                 6666777777777788888888888888999999999999999999888..5666666644444...444779********98 PP

>> Med8  Mediator of RNA polymerase II transcription complex subunit 8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.8   2.3   1.8e-06     0.016      91     187 ..      66     159 ..      57     180 .. 0.71

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 1.8e-06
        Med8  91 kltegRvpvfsHevvpdlLRtKldPevEekeaqleakarnlggeatlekqeaglnkv..vtgllrkl......ekareeweeeeeeraeekqtssladt 181
                  lt++ + +f H+ ++ lLR +   + Ee e q  ++ar++++  t  k    + k   ++ l+rk       ++a+  ++ee ++r +e +t      
  EEA22075.1  66 TLTDEQIEIFRHSEIHALLRERERLREEEAEEQSDVEARDIESGKT-SKVDGDIRKAadISALKRKSvegsedSSAKRAKDEEGTARPSECDT------ 157
                 69********************************************.9999999998445678887744444433333334443333333332...... PP

        Med8 182 ealvaa 187
                     aa
  EEA22075.1 158 ----AA 159
                 ....22 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (185 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       995  (0.0554967); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.31s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1225.04
//
Query:       EEA22076.1  [L=149]
Description: hypothetical protein PMAA_058560 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (149 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       250  (0.0139439); expected 358.6 (0.02)
Passed bias filter:                      210  (0.0117129); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.44
# Mc/sec: 1012.83
//
Query:       EEA22077.1  [L=78]
Description: hypothetical protein PMAA_058570 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (78 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       380  (0.0211947); expected 358.6 (0.02)
Passed bias filter:                      267  (0.0148921); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.37u 0.24s 00:00:00.61 Elapsed: 00:00:00.41
# Mc/sec: 575.04
//
Query:       EEA22078.1  [L=421]
Description: NAD dependent epimerase/dehydratase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.8e-06   27.6   0.0    2.5e-06   27.1   0.0    1.2  1  Epimerase       NAD dependent epimerase/dehydratase family
    4.2e-05   23.5   0.0    6.6e-05   22.9   0.0    1.3  1  NAD_binding_10  NAD(P)H-binding
  ------ inclusion threshold ------
      0.078   13.4   0.0        0.2   12.1   0.0    1.7  1  Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domai
      0.094   13.1   0.0       0.17   12.2   0.0    1.3  1  DUF1456         Protein of unknown function (DUF1456)
       0.14   12.4   0.0       0.42   10.9   0.0    1.8  2  PK_C            Pyruvate kinase, alpha/beta domain
       0.14   12.0   0.0        0.3   11.0   0.0    1.5  1  KR              KR domain
       0.19   10.9   0.0       0.29   10.3   0.0    1.3  1  NAD_binding_4   Male sterility protein


Domain annotation for each model (and alignments):
>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.1   0.0   9.9e-10   2.5e-06       1     136 [.       4     141 ..       4     165 .. 0.76

  Alignments for each domain:
  == domain 1  score: 27.1 bits;  conditional E-value: 9.9e-10
                 EEEETTTSHHHHHHHHHHHHCT..SEEEEEES-STTTTCHHCHHCEEEE--TT-HH..HHHHHHHHH..T-SEEEE--S---HHHHHHSHHHHHHHHTH CS
   Epimerase   1 ilVtGatGfiGsalvkallekg..yevigldrlssasntarledlelveldltdrs..alerlfkee..qpdavihlAavggvaassedpadfieknlq 93 
                 +lVtGatG  G a+v+++ +     +v++l+r ++  ++++    +  ++dl+++   +l +lf+    ++d+v+  A  +++++   +     e+n+ 
  EEA22078.1   4 ALVTGATGISGHAIVEHIVKLPdwTKVVTLSRSRQVTPHSKV---THLTADLLNDPttSLIDLFRADaqEIDYVFFSAYLANPDEDKAS-----EINTG 94 
                 59*******************995559999999666666554...5678898887767777777655469*******999988885555.....78999 PP

                 HHHHHHHHHHHH....TCTEEEEEEEGGGGTSCSSSSBSTCSTTS-- CS
   Epimerase  94 gtlnlleaarka....gvkrllflsSsevYGkdaeqpkeettltgpl 136
                 + +n ++a+rk+     +kr++ +     YG    qpk+ + +++p+
  EEA22078.1  95 MLRNFINALRKSgaikSIKRIILVTGLKQYGVHLGQPKQPMHESDPW 141
                 99999999998843334559999999999998888776666666665 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.0   2.6e-08   6.6e-05       1     109 [.       8     131 ..       8     173 .. 0.65

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 2.6e-08
                     TTTSHHHHHHHHHHHHC-.T-EEEEEETTHHHCHHHHCTTTCEEEE--TT-..CCHHHHHHT....T-SEEEES-..--TCCHHHH......HHH CS
  NAD_binding_10   1 GAtGkvGrllvkellarg.ghevtalvRnpeklaeleaeeglevvegdvtd..vedlaealk....gadaVvsal..ggggkdeeg......akn 80 
                     GAtG  G+++v+++++    ++v+ l R+ + ++    +++++ +++d+++  + +l + ++     +d V++++  ++ ++d+ +       +n
      EEA22078.1   8 GATGISGHAIVEHIVKLPdWTKVVTLSRSRQVTP----HSKVTHLTADLLNdpTTSLIDLFRadaqEIDYVFFSAylANPDEDKASeintgmLRN 98 
                     9****************95556666666666655....799********9844466766665444499***999988444443333556667*** PP

                     HHHHHHHCT....--EEEEEEETTTTSGCGCHH CS
  NAD_binding_10  81 ivdaakeag....vkRfvlvsaigvgdevpgef 109
                      ++a++++g    +kR++lv++++ +  + g+ 
      EEA22078.1  99 FINALRKSGaiksIKRIILVTGLKQYGVHLGQP 131
                     ******97755559********98775433332 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   7.8e-05       0.2       4      74 ..       6      78 ..       3      85 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 7.8e-05
                    EETTTSHHHHHHHHHHHCTSSEEEEEEEESTT..TTTSBHHHHSGGGTTTECEBEEEGGGGGCTT-SEEEE-S CS
  Semialdhyde_dh  4 ivGatGyvGqellrlLeehpevelvvllsssr..saGkklaeavkaleegkdlkvedvdeeelkevdivflal 74
                    + GatG  G ++++ + + p+++ vv ls+sr     +k++ +   l +  + ++ d   ++ +e+d+vf+++
      EEA22078.1  6 VTGATGISGHAIVEHIVKLPDWTKVVTLSRSRqvTPHSKVTHLTADLLNDPTTSLIDLFRADAQEIDYVFFSA 78
                    77****************9999999999999923333444444446666666666677778889******986 PP

>> DUF1456  Protein of unknown function (DUF1456)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   6.7e-05      0.17      17      62 ..      58     103 ..      52     106 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 6.7e-05
     DUF1456  17 edmveifklggvevtkeelsalLkkedeegyeeckdqvLesFLnGl 62 
                 + ++++f++   e++    sa+L ++de+++ e++  +L++F+n l
  EEA22078.1  58 TSLIDLFRADAQEIDYVFFSAYLANPDEDKASEINTGMLRNFINAL 103
                 678999999999999999**************************88 PP

>> PK_C  Pyruvate kinase, alpha/beta domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00016      0.42      67     105 ..      85     123 ..      19     128 .. 0.76
   2 ?   -2.2   0.0       1.9   4.8e+03      56      92 ..     369     411 ..     355     415 .. 0.64

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00016
                 HHHH...TTS.HHHHHHHHHHHTTSS-STSEEEEEE-SSS CS
        PK_C  67 kaktaestde.llreavkvakeaglvkkgdevvvtaGtpk 105
                 ++k a+++++ +lr++++++ ++g +k+ +++++++G ++
  EEA22078.1  85 EDK-ASEINTgMLRNFINALRKSGAIKSIKRIILVTGLKQ 123
                 333.45666679*************************875 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.9
                 HCTTEEHHH.HHHHH..........TTSHHHHHHHHHHHTTSS- CS
        PK_C  56 lyrGvypvlvekakt.......aestdellreavkvakeaglvk 92 
                 l+r  ++v   ++k+       +++t e+++e ++++ ++g+++
  EEA22078.1 369 LSREFSCVV-SMSKArklgwtgYKDTWEAFEETFDALEKEGILP 411
                 555555553.4444456777776777777888888888888876 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00012       0.3       2      48 ..       3      48 ..       2      83 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00012
                EEEEETTTSHHHHHHHHHHHHHH.S-EEEEE-SS..--HHHHHHHHHH CS
          KR  2 tylitGGlGgLGlelarwlaekg.arhlvllsRsaaadedskaliael 48
                t l+tG++G  G ++++++++    +++v lsRs +++++sk  +++l
  EEA22078.1  3 TALVTGATGISGHAIVEHIVKLPdWTKVVTLSRSRQVTPHSK--VTHL 48
                579******************98799********87766655..3333 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   0.00011      0.29       1      41 [.       6      45 ..       6      72 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00011
                   EE-TTSHHHHHHHHHHHHHS-.TEEEEEE-SSSHHHHHHHH CS
  NAD_binding_4  1 lTGaTGFLGkvLlekLLrttpevkiyllvRaksgesaeeRl 41
                   +TGaTG  G  ++e +++  +  k++ l R+++  ++  ++
     EEA22078.1  6 VTGATGISGHAIVEHIVKLPDWTKVVTLSRSRQV-TPHSKV 45
                   7******************8755*****998855.665555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (421 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       526  (0.0293379); expected 358.6 (0.02)
Passed bias filter:                      468  (0.026103); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.55u 0.25s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2888.07
//
Query:       EEA22079.1  [L=481]
Description: hypothetical protein PMAA_058590 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
     0.0082   16.2   0.7     0.0082   16.2   0.7    3.7  4  bZIP_2          Basic region leucine zipper
  ------ inclusion threshold ------
      0.026   14.6   0.2      0.026   14.6   0.2    3.3  3  bZIP_1          bZIP transcription factor
        0.5   10.7   4.1       0.82   10.0   0.3    2.8  2  ATP-synt_E      ATP synthase E chain
       0.54   10.5   4.7        1.7    8.9   0.5    2.9  2  Cnn_1N          Centrosomin N-terminal motif 1
          2    8.3   9.7         23    4.8   0.3    3.6  3  DivIC           Septum formation initiator
        2.5    8.0   5.5        5.4    7.0   0.1    3.0  3  Shugoshin_N     Shugoshin N-terminal coiled-coil region
        6.4    6.8  15.3       0.18   11.9   0.8    3.1  4  ADIP            Afadin- and alpha -actinin-Binding


Domain annotation for each model (and alignments):
>> bZIP_2  Basic region leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.1      0.47   1.2e+03      28      50 ..     247     269 ..     244     271 .. 0.69
   2 ?   -2.2   0.5       1.9   4.7e+03      23      38 ..     299     313 ..     292     324 .. 0.54
   3 !   16.2   0.7   3.2e-06    0.0082      25      50 ..     366     391 ..     365     395 .. 0.91
   4 ?    3.8   1.3     0.023        59      31      52 ..     440     461 ..     431     463 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.47
                 HHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_2  28 eeleervkeLeeeNaqLrqkveq 50 
                 + l++ +  Le e++ L+ k e+
  EEA22079.1 247 AALQQHITTLELEKSSLLSKREA 269
                 45777777777777777776665 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.9
                 HHHHHHHHHHHHHHHH CS
      bZIP_2  23 kkakeeeleervkeLe 38 
                 +k+++e+l++ v eL+
  EEA22079.1 299 RKLRDEDLQN-VLELR 313
                 3444444443.33333 PP

  == domain 3  score: 16.2 bits;  conditional E-value: 3.2e-06
                 HHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_2  25 akeeeleervkeLeeeNaqLrqkveq 50 
                 ak++ le+rv eLe+ Na Lrqk+e+
  EEA22079.1 366 AKTAALEQRVLELESANADLRQKIEK 391
                 6899********************97 PP

  == domain 4  score: 3.8 bits;  conditional E-value: 0.023
                 HHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_2  31 eervkeLeeeNaqLrqkveqLe 52 
                   ++++++ eN +L+q+v++++
  EEA22079.1 440 SAEIEDVKCENLRLKQQVQKMK 461
                 56899999***********997 PP

>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.2      0.55   1.4e+03      29      52 ..     247     270 ..     244     276 .. 0.78
   2 ?   14.6   0.2     1e-05     0.026      26      56 ..     366     396 ..     362     398 .. 0.90
   3 ?    1.9   0.8     0.096   2.5e+02      40      63 ..     441     464 ..     433     465 .. 0.81

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.55
                 HHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  29 eeLerrvkaLekeNksLkseleel 52 
                 ++L++   +Le e +sL s+ e l
  EEA22079.1 247 AALQQHITTLELEKSSLLSKREAL 270
                 578999999999999998887776 PP

  == domain 2  score: 14.6 bits;  conditional E-value: 1e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  26 aeieeLerrvkaLekeNksLkseleelkkev 56 
                 a++++Le+rv +Le+ N++L++++e+  +e+
  EEA22079.1 366 AKTAALEQRVLELESANADLRQKIEKSGNEI 396
                 67899********************987776 PP

  == domain 3  score: 1.9 bits;  conditional E-value: 0.096
                 HHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  40 keNksLkseleelkkevekLkskv 63 
                 +e ++ k e+ +lk +v+k+k ++
  EEA22079.1 441 AEIEDVKCENLRLKQQVQKMKYQL 464
                 667788889999999999999876 PP

>> ATP-synt_E  ATP synthase E chain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.3      0.28   7.3e+02      28      68 ..     342     379 ..     337     406 .. 0.59
   2 ?   10.0   0.3   0.00032      0.82      43      82 ..     434     473 ..     422     479 .. 0.85

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.28
  ATP-synt_E  28 rqrslkseekkeekereleaqekliekakaayakkkqakse 68 
                  +r+++   k++  ++ +  ++ l + ak+a   ++  + e
  EEA22079.1 342 SYRRME---KAQSLSSAQSSNQDLWQTAKTAALEQRVLELE 379
                 555555...55555666666666777777776655554443 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00032
  ATP-synt_E  43 releaqekliekakaayakkkqakseakslaegssakidd 82 
                 re e   ++ie+ k +  + kq+ +++k++ e s+a i+ 
  EEA22079.1 434 RERESHSAEIEDVKCENLRLKQQVQKMKYQLETSQAVIEC 473
                 555666677*************************988775 PP

>> Cnn_1N  Centrosomin N-terminal motif 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.3      0.11   2.9e+02      37      65 ..     367     395 ..     345     401 .. 0.65
   2 ?    8.9   0.5   0.00066       1.7      32      63 ..     437     468 ..     425     474 .. 0.78

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.11
      Cnn_1N  37 qkeellkenielkveveslqkelkekkkl 65 
                 +  +l++   el+  +++l++++++  ++
  EEA22079.1 367 KTAALEQRVLELESANADLRQKIEKSGNE 395
                 34455555667777777777777766554 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.00066
      Cnn_1N  32 klseeqkeellkenielkveveslqkelkekk 63 
                 ++++ ++e++  en  lk++v++++ +l++ +
  EEA22079.1 437 ESHSAEIEDVKCENLRLKQQVQKMKYQLETSQ 468
                 33447799999999999999999999998766 PP

>> DivIC  Septum formation initiator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.1     0.037        96      23      52 ..     243     272 ..     240     279 .. 0.83
   2 ?    4.8   0.3    0.0091        23      25      50 ..     367     392 ..     355     408 .. 0.67
   3 ?    4.5   0.8     0.012        30      25      52 ..     435     462 ..     429     472 .. 0.69

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.037
                 HHHHHHHHHHHHHHHHHHHHHHHHHCC-XX CS
       DivIC  23 kqeiaalqaelaklkaeneeLeaevkdLks 52 
                  ++ aalq+++ +l  e+ +L ++ + L s
  EEA22079.1 243 AADHAALQQHITTLELEKSSLLSKREALYS 272
                 578899*************99999998865 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.0091
                 HHHHHHHHHHHHHHHHHHHHHHHCC- CS
       DivIC  25 eiaalqaelaklkaeneeLeaevkdL 50 
                 + aal++ + +l   n++L +++++ 
  EEA22079.1 367 KTAALEQRVLELESANADLRQKIEKS 392
                 45566666666666666666666554 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.012
                 HHHHHHHHHHHHHHHHHHHHHHHCC-XX CS
       DivIC  25 eiaalqaelaklkaeneeLeaevkdLks 52 
                 e++   ae++ +k en +L+++v+++k 
  EEA22079.1 435 ERESHSAEIEDVKCENLRLKQQVQKMKY 462
                 5566667777777777777777777754 PP

>> Shugoshin_N  Shugoshin N-terminal coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.2       1.4   3.7e+03      22      35 ..     252     265 ..     248     270 .. 0.79
   2 ?    7.0   0.1    0.0021       5.4      19      44 ..     364     389 ..     362     389 .. 0.89
   3 ?    2.7   0.1     0.046   1.2e+02      29      44 ..     442     457 ..     440     458 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 1.4
  Shugoshin_N  22 kirelekevseLls 35 
                   i +le e s+Lls
   EEA22079.1 252 HITTLELEKSSLLS 265
                  58899999999998 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0021
  Shugoshin_N  19 lslkirelekevseLlsENlnLReli 44 
                  +++k   le +v eL s N +LR++i
   EEA22079.1 364 QTAKTAALEQRVLELESANADLRQKI 389
                  67778899***************997 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.046
  Shugoshin_N  29 evseLlsENlnLReli 44 
                  e+++ + ENl L++++
   EEA22079.1 442 EIEDVKCENLRLKQQV 457
                  8999**********98 PP

>> ADIP  Afadin- and alpha -actinin-Binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.2      0.88   2.3e+03      95     105 ..     244     254 ..     188     276 .. 0.57
   2 ?   -2.1   0.3       1.5   3.8e+03      79      79 ..     270     270 ..     236     320 .. 0.58
   3 ?    4.3   1.1     0.015        38      84     125 ..     353     396 ..     340     405 .. 0.71
   4 ?   11.9   0.8   7.1e-05      0.18      50      90 ..     431     471 ..     423     480 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.88
        ADIP  95 akerqlekklk 105
                 a+++ l++ ++
  EEA22079.1 244 ADHAALQQHIT 254
                 22222222222 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.5
        ADIP  79 l 79 
                 l
  EEA22079.1 270 L 270
                 2 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.015
        ADIP  84 eqlerela..lvqakerqlekklktleqklknekeelqrlknal 125
                 ++ ++ ++   ++ak++ le+++ +le+++  +++++++  n +
  EEA22079.1 353 SSAQSSNQdlWQTAKTAALEQRVLELESANADLRQKIEKSGNEI 396
                 33333333324567889999999999999999999999987765 PP

  == domain 4  score: 11.9 bits;  conditional E-value: 7.1e-05
        ADIP  50 rdleqreslnetirkleaeierlqskierlktqleqlerel 90 
                 r +++res++++i++ ++e+ rl+++++++k qle ++  +
  EEA22079.1 431 RAMRERESHSAEIEDVKCENLRLKQQVQKMKYQLETSQAVI 471
                 66899******************************999765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (481 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1278  (0.0712812); expected 358.6 (0.02)
Passed bias filter:                      448  (0.0249875); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.43
# Mc/sec: 3382.74
//
Query:       EEA22080.1  [L=814]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-07   30.8   0.4    4.1e-07   29.3   0.4    1.7  1  Fungal_trans  Fungal specific transcription factor domain
      8e-07   29.1   9.8      8e-07   29.1   9.8    2.1  2  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.3   0.4   4.6e-11   4.1e-07      37     176 ..     338     463 ..     330     469 .. 0.84

  Alignments for each domain:
  == domain 1  score: 29.3 bits;  conditional E-value: 4.6e-11
  Fungal_trans  37 pllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLlllelyektssdralherhhgvavrlarslgLhrnp 133
                    + l+aila G++ s+   ke +s     +  +++++lr   ++     s++s ++++q+Ll++  +++   +   ++ ++gva r++ +lgLh ++
    EEA22080.1 338 IGILFAILASGSQVSDFSRKERSSMCQLYV-SCAYQCLRNGNFL-----SQPS-MEAIQTLLIIGDVLSYNMNPGIAYVTFGVAQRMSLTLGLHAES 427
                   57899*********9999998866555544.6778888877777.....6666.******************************************* PP

  Fungal_trans 134 syvgkkslwklweeeaesrrRlwwaaFylDktialklGrpp.ll 176
                   +          +   a +r+ lww+  + D ++ l + rp  +l
    EEA22080.1 428 FLFR-------DQT-ANRRHELWWSMAWQDSHFGLSYDRPIeIL 463
                   9986.......555.889******99888888888888887665 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.1   9.8   8.9e-11     8e-07       1      36 [.      31      67 ..      31      71 .. 0.88
   2 ?   -1.8   0.1      0.41   3.7e+03      18      24 ..     578     585 ..     574     587 .. 0.76

  Alignments for each domain:
  == domain 1  score: 29.1 bits;  conditional E-value: 8.9e-11
                SS-HHHHHCT---STSSSS-HHHHHCT..HHHCCCCTC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkkln..leCtfyses 36
                +aC +C k+KvKCd++ P Cs C+k++    Ctf++ +
  EEA22080.1 31 KACYPCYKRKVKCDRNSP-CSLCVKRGyaHLCTFKHPP 67
                59****************.********87779977655 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.41
                 SS.-HHHH CS
     Zn_clus  18 Pa.CsnCk 24 
                 P+ C++C+
  EEA22080.1 578 PHlCQECI 585
                 77799997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (814 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       771  (0.043003); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.73u 0.30s 00:00:01.03 Elapsed: 00:00:00.49
# Mc/sec: 5045.75
//
Query:       EEA22081.1  [L=247]
Description: dienelactone hydrolase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      3e-32  112.0   0.1    3.4e-32  111.7   0.1    1.0  1  DLH            Dienelactone hydrolase family
  ------ inclusion threshold ------
      0.017   14.5   0.0      0.041   13.2   0.0    1.6  2  DUF915         Alpha/beta hydrolase of unknown function (DUF9
       0.04   13.6   0.0      0.085   12.5   0.0    1.6  1  Abhydrolase_1  alpha/beta hydrolase fold


Domain annotation for each model (and alignments):
>> DLH  Dienelactone hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  111.7   0.1   5.7e-36   3.4e-32       1     216 [.      30     244 ..      30     245 .. 0.90

  Alignments for each domain:
  == domain 1  score: 111.7 bits;  conditional E-value: 5.7e-36
         DLH   1 idaylatpkna.kkpvvvviqeifGvn.dnikdiserlaeeGYvalaPdlYarqaldpndeaeaaraldelvskvaeekvlddlkaavaylksvpevst 97 
                 +++y   p+n+    +v+++++++G + +n + i++++a +GY++++Pdl+ ++   p ++  ++ + + l  +   e+v  +++a++  l+++   ++
  EEA22081.1  30 FEVYTSYPENKsTNYAVLILTDVIGHKfNNAQLIADQFAANGYFVFMPDLFHGDP-VPLNRGPDFVLAKWLEGHG-AERVDPIVEASITELREKY--KV 124
                 678999999999999****************************************.7888888887776666666.99***********999988..89 PP

         DLH  98 kkvgvvGfCmGGalalllaaev.pevdaavafYGlspekeleeaakikapilalfgeeDefipadevekleealkaanvdlelkvYpgagHaFandsre 195
                 kk+++vG+C+G++ ++ +   + +++d   + +++++e   +e + i +p  ++++e D+++p +++++ e  lk+ + ++++++Y+g++H+Fa + + 
  EEA22081.1 125 KKIAAVGYCFGAKYVVRHLHPKqNKIDVGYVAHPSFVE--ADELKAIGGPFSISAAETDTIFPTEKRHESEIILKETGLPYQINLYSGVVHGFAVRADL 221
                 9**************99877665899999999996665..5667789***********************************************98776 PP

         DLH 196 ..syneeaaedawervlelfkqv 216
                      ++a+e+a+ +++e+f+++
  EEA22081.1 222 sdRVAKYAKENAFLQAVEWFEEY 244
                 55899***************998 PP

>> DUF915  Alpha/beta hydrolase of unknown function (DUF915)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   6.9e-06     0.041      91     126 ..     113     148 ..     107     182 .. 0.87
   2 ?   -2.4   0.0      0.41   2.4e+03     198     230 ..     178     210 ..     167     213 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 6.9e-06
      DUF915  91 kvlseLkkkYnikkfnavGhSmGglaltsYleeyad 126
                 + ++eL++kY++kk+ avG+  G+  +++ l   ++
  EEA22081.1 113 ASITELREKYKVKKIAAVGYCFGAKYVVRHLHPKQN 148
                 5689********************999988876555 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.41
      DUF915 198 kqsDgivplasseslkyllkknaksyteslikg 230
                  ++D i p++    ++ +lk+++  y+  l+ g
  EEA22081.1 178 AETDTIFPTEKRHESEIILKETGLPYQINLYSG 210
                 578999999999999999999988888777766 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   1.4e-05     0.085      20      85 ..      62     137 ..      49     151 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.4e-05
                    HHHHHHHHTTSEEEEEEETTSTTSSSTTTGB.CHH...............SHHHHHHHHHHHHHHCTTSSEEEEEETHHHH CS
  Abhydrolase_1  20 glapaLakdgfdvillDlrGvgySspapacinddy...............gtasvaddldrildalgddkltlvGhSmGGm 85 
                    ++a+ +a +g++v+++Dl    +++p p  + +d+               ++  v++++  ++++++++k++ vG+++G  
     EEA22081.1  62 LIADQFAANGYFVFMPDLF---HGDPVPLNRGPDFvlakwleghgaervdPI--VEASITELREKYKVKKIAAVGYCFGAK 137
                    5666677778888888886...455555444477777888888877777777..999999*******************75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (247 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       485  (0.0270511); expected 358.6 (0.02)
Passed bias filter:                      459  (0.025601); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 1603.45
//
Query:       EEA22082.1  [L=225]
Description: ThiJ/PfpI family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.8e-15   57.1   0.0    3.4e-15   56.2   0.0    1.4  1  DJ-1_PfpI  DJ-1/PfpI family


Domain annotation for each model (and alignments):
>> DJ-1_PfpI  DJ-1/PfpI family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.2   0.0   1.9e-19   3.4e-15      10     164 ..      37     196 ..      13     197 .. 0.78

  Alignments for each domain:
  == domain 1  score: 56.2 bits;  conditional E-value: 1.9e-19
                 TBEHHHHHHHHHHHHHTTEEEEEEESS....TSEEEETTSEEEE-SEEGGGCTCCG-SEEEE--BHHHHHHHHTSHHHHHHHHHHHHTT-EEEEETTTH CS
   DJ-1_PfpI  10 gvedvElivpvdvlkragikvdvvsvd....keevkgsrGlkvtvdaslddvkaaeyDalvlpGGragperlrenekvvelvkefaekgklvaaICagp 104
                  ++ +El++ ++ l   + +v +v +d     ++  ++ G +v++++++d+  +a+  +l++pGG     + +    v+e++ +++ + + + ++C+g 
  EEA22082.1  37 RYKKIELSIIAATLDPVSTDVAAVFPDkqdvWNPAGSKIGQSVVPTHTFDN-PPAKIEVLLVPGGSG-TRSEASAVPVIEFIAKVYPSLRYLLTVCTGS 133
                 3455555555555555777777777775555555578999**********7.8899*********99.444444569********************** PP

                 HHHHHTTTTTTSEE--SGGGHHHH..HHTTSEE-SS.SEEEETTEEEESSGGGHHHHHHHHHH CS
   DJ-1_PfpI 105 qlLaaagvlkgrrvTsypavkdkl..ekagakyvdk.rvvvdgnlvTsrgpgaaiefalelle 164
                  l a+agvl+g+r+Ts++   +++       +++ + r v +gn+ +s+g  a ++++++++e
  EEA22082.1 134 GLAARAGVLDGKRATSNKRAWNEViaLRDEPTWIRRaRWVAEGNIWSSSGISAGMDMMFAYVE 196
                 ********************99995444556677779**********************9997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (225 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       225  (0.0125495); expected 358.6 (0.02)
Passed bias filter:                      201  (0.0112109); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.30s 00:00:00.79 Elapsed: 00:00:00.49
# Mc/sec: 1367.14
//
Query:       EEA22083.1  [L=1400]
Description: multidrug resistance-associated protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.4e-44  149.4   0.1      7e-21   75.2   0.0    2.8  2  ABC_tran         ABC transporter
      5e-31  108.4  20.0    6.2e-20   72.0   7.3    2.4  2  ABC_membrane     ABC transporter transmembrane region
      1e-10   41.4   3.3    0.00079   18.9   0.9    4.2  3  SMC_N            RecF/RecN/SMC N terminal domain
    5.3e-08   33.0   2.8      0.044   13.6   0.0    4.2  4  AAA_21           AAA domain, putative AbiEii toxin, Type IV T
    1.6e-07   30.9   3.9     0.0014   18.4   0.1    2.8  2  AAA_29           P-loop containing region of AAA domain
    6.9e-07   29.3   0.6      0.026   14.4   0.0    2.5  2  RsgA_GTPase      RsgA GTPase
    2.1e-06   28.0   0.2      0.079   13.2   0.1    3.2  2  AAA_22           AAA domain
    2.5e-06   27.7   2.6      0.054   13.6   0.4    2.7  2  DUF87            Helicase HerA, central domain
    8.4e-06   24.9   0.7      0.062   12.2   0.0    2.5  2  TrwB_AAD_bind    Type IV secretion-system coupling protein DN
    1.1e-05   24.7   0.5     0.0082   15.2   0.1    2.5  2  T2SSE            Type II/IV secretion system protein
    1.3e-05   25.4   0.2       0.17   12.1   0.0    3.4  2  SbcCD_C          Putative exonuclease SbcCD, C subunit
    7.7e-05   22.3   0.2       0.28   10.7   0.1    2.5  2  AAA_7            P-loop containing dynein motor region
    9.5e-05   21.9   4.1      0.079   12.3   0.1    2.6  2  FtsK_SpoIIIE     FtsK/SpoIIIE family
    9.6e-05   22.8   0.7        0.3   11.4   0.0    3.0  2  AAA_16           AAA ATPase domain
    0.00014   21.9   1.0       0.32   11.1   0.0    2.9  2  MMR_HSR1         50S ribosome-binding GTPase
    0.00087   19.8   1.5        1.3    9.5   0.1    2.7  2  AAA_23           AAA domain
      0.002   17.8   1.0       0.25   10.9   0.0    2.4  2  cobW             CobW/HypB/UreG, nucleotide-binding domain
     0.0025   17.5   0.1        5.8    6.6   0.0    3.3  3  Sigma54_activat  Sigma-54 interaction domain
     0.0031   17.4   0.9        1.7    8.6   0.0    3.0  2  NTPase_1         NTPase
     0.0034   16.7   0.1        2.3    7.4   0.0    2.5  2  Zeta_toxin       Zeta toxin
     0.0036   17.3   1.0          3    7.9   0.0    4.4  4  AAA_5            AAA domain (dynein-related subfamily)
     0.0045   16.7   0.6        1.8    8.2   0.2    2.6  2  AAA_30           AAA domain
     0.0047   16.1   0.3        1.3    8.2   0.1    2.3  2  DUF815           Protein of unknown function (DUF815)
     0.0052   17.1   0.1        5.1    7.5   0.0    2.7  2  RNA_helicase     RNA helicase
     0.0065   17.0   0.1        2.6    8.6   0.0    2.7  2  AAA_18           AAA domain
     0.0077   16.4   0.1        2.3    8.4   0.0    3.1  2  AAA_33           AAA domain
     0.0097   15.5   0.2       0.11   12.0   0.0    2.5  2  AAA_25           AAA domain
  ------ inclusion threshold ------
      0.012   14.6   0.6       0.44    9.4   0.1    2.5  2  AAA_10           AAA-like domain
      0.022   15.0   1.8          1    9.6   0.3    2.7  2  AAA_28           AAA domain
      0.026   14.3   0.4          1    9.1   0.0    2.5  2  AAA_24           AAA domain
       0.03   13.8   1.9        3.2    7.1   0.1    2.5  2  Pox_A32          Poxvirus A32 protein
      0.034   14.0   0.5       0.48   10.3   0.0    2.4  2  MobB             Molybdopterin guanine dinucleotide synthesis
       0.04   14.2   0.8        6.2    7.2   0.2    2.9  2  AAA_19           AAA domain
      0.043   13.7   4.2        4.8    7.1   0.1    3.1  3  NACHT            NACHT domain
      0.059   13.1   0.9         10    5.8   0.1    3.0  2  IstB_IS21        IstB-like ATP binding protein
      0.082   12.1   3.3       0.59    9.3   0.2    2.9  4  DUF2075          Uncharacterized conserved protein (DUF2075)
      0.083   12.6   0.5        5.8    6.6   0.0    2.6  2  Viral_helicase1  Viral (Superfamily 1) RNA helicase
      0.096   12.4   1.1         10    5.9   0.1    2.7  2  DEAD             DEAD/DEAH box helicase
       0.12   12.3   0.5         21    4.9   0.0    3.0  3  ATPase_2         ATPase domain predominantly from Archaea
       0.12   11.7   0.2         13    5.1   0.1    2.5  2  Mg_chelatase     Magnesium chelatase, subunit ChlI
       0.13   11.9   0.2         14    5.3   0.1    2.5  2  ATP-synt_ab      ATP synthase alpha/beta family, nucleotide-b
       0.19   11.8   0.0       0.19   11.8   0.0    1.9  1  CbiA             CobQ/CobB/MinD/ParA nucleotide binding domai
        1.5    9.2   5.2        5.8    7.4   0.4    3.8  2  AAA              ATPase family associated with various cellul
        1.9    7.8   5.0         14    4.9   0.1    3.2  4  ATPase           KaiC


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.4   0.0   2.5e-22     1e-19       1     135 [.     589     721 ..     589     723 .. 0.90
   2 !   75.2   0.0   1.7e-23     7e-21       2     137 .]    1180    1328 ..    1179    1328 .. 0.87

  Alignments for each domain:
  == domain 1  score: 71.4 bits;  conditional E-value: 2.5e-22
                 EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH......HHHTCHHHHHHHST CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxx RF
    ABC_tran   1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren......esdeeiekalsklg 93 
                 l++vslk+ +g  v+i+G +G+GKS L+k+l+g+++  +G++            ++++++ig++ q   l + l + +n      +s+e+ +k+l+   
  EEA22083.1 589 LHDVSLKVLKGDHVVITGGTGSGKSLLMKALLGEVEFMAGTV------------RVSSARIGYCGQSIWLENAL-MLDNafrcasDSEEWRHKILDACA 674
                 789***************************************............78999**************9.77777***9878888888888888 PP

                 TGG.....TTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEEST CS
                 xxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  94 lke.....lkdtvvksspssLSgGqkqrvalarallkkpkllllDEp 135
                 l+e     +  ++++s++  LSgG++qr+ lar+++++p++++lD+ 
  EEA22083.1 675 LTEllntsDSGETIGSGGICLSGGERQRLGLARTIAQRPDIIILDDV 721
                 888655656777888888***************************85 PP

  == domain 2  score: 75.2 bits;  conditional E-value: 1.7e-23
                  EEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH......HHHTCHHHHHHHS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxx RF
    ABC_tran    2 knvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren......esdeeiekalskl 92  
                  + ++l++++gekvai G++G+GKStL+ +l+ l+++ +G+i +d+ d+++ + + lr+++ v++q++ +  ++ vr+        s+++i   l+  
  EEA22083.1 1180 DGINLTIHPGEKVAICGRSGSGKSTLILTLLSLMENRKGTIMIDDIDISRLKPSLLRSRFHVISQDTYIHGDT-VRDPfdpkgtSSNDKIWSTLEDC 1275
                  789***************************************************************6666666.***9***9998888888888888 PP

                  TTGGTTCBGESTTS....GGS-HHHHHHHHHHHHHHHTSS....EEEEESTTT CS
                  xxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxx RF
    ABC_tran   93 glkelkdtvvkssp....ssLSgGqkqrvalarallkkpk....llllDEpta 137 
                  +lk++ +t  + ++     sLS G+ q  alar++l++ +    ++l+DE+t+
  EEA22083.1 1276 SLKQKIETSGGLDTpltdISLSAGEMQLFALARTILNAEQspggIVLFDEATS 1328
                  8888444444333355569******************987667799****995 PP

>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.0   4.7     2e-13   8.3e-11       5     273 ..     240     505 ..     236     506 .. 0.91
   2 !   72.0   7.3   1.5e-22   6.2e-20      73     270 ..     911    1106 ..     844    1110 .. 0.88

  Alignments for each domain:
  == domain 1  score: 42.0 bits;  conditional E-value: 2e-13
                   HHHHHHHHHHHHHHHHHHHHHHHHHHSSTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHHHHSCHHHHH CS
  ABC_membrane   5 illailagvlsplfplvlgrildtlldkgdpetealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsffdtnsvGell 101
                   i+  ++ ++  +++p+++  ++  l+d+ + ++ +   ++ + ll++ + ++++  +s+l ++    ++  l   +f+k+lr+     d+   ++ l
    EEA22083.1 240 IFPRLCLTGFTFAQPFITTALIRYLSDS-MESKNDGYGLMGASLLVYGGIAVSNSRYSHLTYKSITIIRGGLVDAVFDKVLRL---REDKEMESRAL 332
                   677788888999*************995.4444478899999999999999999999999999********************...44778899999 PP

                   HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHTTT CS
  ABC_membrane 102 srltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirtVkafgr 198
                   ++  ndv++++++l++ + l+   l t +++ +++  +g++  l +l+++++   +s +i+k + k ++k + a++k+ + ++ +ls ++ +k  g 
    EEA22083.1 333 TLTINDVQRISSSLTYLHELWAGLLETGLATWLLWRQVGPS-CLTVLGLALVSTAISTYIGKSTGKQQQKWMAATEKRIATTRKMLSSLKAIKTTGS 428
                   9999************************************9.5****************************************************** PP

                   HHHHHHHHHHHHHHHH..HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSTHHHHHHHHHHHHHHHHH CS
  ABC_membrane 199 eeyflekfekaleeak..kagikkaianglligitqllgllsyalalwfGttlvisgelsvgdlvvflslfailfga 273
                   e+++ + ++  + ++   +++++++++ ++l++ t+l  + + ++ +++Gt l+ +++l+++ l+  l l+++l ++
    EEA22083.1 429 EQRVSSTIQTLRVREFaaSKMFRALLVGSVLSSYTTLTLSPVLVFGAYIGTMLSYQQNLDPSRLFSSLILISLLATP 505
                   *********98876651167899****************************************99999999999877 PP

  == domain 2  score: 72.0 bits;  conditional E-value: 1.5e-22
                    HHHHHHHHHHHHHCSTHHHHHHSCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane   73 skrlrrklfkkilrqpmsffdtnsvGellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkk 167 
                     + l+ +l+k +l++  +f +++++G+ll+r++ d+  ++ +l+ +l+  +  llt+v+ ++++ +  ++   vl a++  ++l++ ++ +++k+
    EEA22083.1  911 GVGLHLQLLKTVLNATFRFVSSTDSGDLLNRFNQDLMMIDMSLPLNLFNTIAELLTCVIQVVLVAVAAVYALAVLPALTTALYLIQHFYLRTSKQ 1005
                    4569******************************************************************************************* PP

                    HHHHHHHHHHHHHHHHHHHHHTHHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSTHHHHHH CS
  ABC_membrane  168 lkkkeqkavakassvaeEslsgirtVkafgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttlvisgelsvgdlvv 262 
                    l++ e ++ a + + + E+  g+ t++a  ++++f+++f + l++ ++  +    ++ +l+ +++l+++++ + +  +G++l i+++ s+g + v
    EEA22083.1 1006 LRQHELQSKASLQTKLMETCAGLVTIRAHQWQSTFRSEFREHLDRSQEPIYLLYAVQCWLQLTLDLVVTALSVTV--VGVALGIKDKTSLGAIGV 1098
                    *********************************************************************999998..9*************9777 PP

                    HHHHHHHH CS
  ABC_membrane  263 flslfail 270 
                      + +++l
    EEA22083.1 1099 AFLNLTTL 1106
                    66666665 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.0     0.012       5.1      23      49 ..     598     621 ..     586     636 .. 0.80
   2 !    9.0   0.0    0.0021      0.86     136     211 ..     694     770 ..     647     778 .. 0.73
   3 !   18.9   0.9   1.9e-06   0.00079     135     209 ..    1280    1368 ..    1176    1376 .. 0.71

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.012
                 TSSEEEEEESTTSSHHHHHHHHHHHCT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  23 sksftaivGpNGSGKsnlldAilFvLG 49 
                 +  + +i+G  GSGKs l+ A+   LG
  EEA22083.1 598 KGDHVVITGGTGSGKSLLMKAL---LG 621
                 456789***************9...55 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.0021
                 CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHH...HHCTTSEEEEE..-SSHHHCCC-SCEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxx..xxxxxxxxxxxxxxxx RF
       SMC_N 136 lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellk...eksknaQfivi..slreemlekadklvgv 211
                  LSgGe++ + la  +A    ++  + +lD++ +aLD+k vk + e+l          Q+ +i  + +++  + ad+++++
  EEA22083.1 694 CLSGGERQRLGLARTIA----QRPDIIILDDVFSALDKKTVKHIRERLFgpnGLLRLLQVTIIetTQDQRWATMADQVFRI 770
                 59999999777776654....566699*****************9988622223334555444113333344445666665 PP

  == domain 3  score: 18.9 bits;  conditional E-value: 1.9e-06
                  T..............CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC-SCEE CS
                  x..............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  135 e..............lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQfivislreemlekadklv 209 
                  +              +LS Ge +L ala  +   + +p  ++l+De  + +D +  +k+ +l++e+ k+  ++ i +r e+  + d+++
  EEA22083.1 1280 KietsggldtpltdiSLSAGEMQLFALARTILNAEQSPGGIVLFDEATSSIDVETETKIMRLIRERLKEKTVLSILHRLETALEYDRVL 1368
                  2444444444444448************999999999**************************************99999988887766 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.6   0.0    0.0073         3       3      29 ..     603     623 ..     602     667 .. 0.82
   2 ?    0.3   0.0       1.2   4.9e+02     238     283 ..     696     742 ..     694     757 .. 0.68
   3 !    7.4   0.4    0.0085       3.5       3      22 ..    1193    1212 ..    1192    1243 .. 0.75
   4 !   13.6   0.0   0.00011     0.044     224     283 ..    1281    1344 ..    1246    1354 .. 0.84

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0073
      AAA_21   3 vliGpNgsGKSnLLdaldllarldrdv 29 
                 v++G  gsGKS L++al      +++v
  EEA22083.1 603 VITGGTGSGKSLLMKAL------LGEV 623
                 9****************......4444 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 1.2
      AAA_21 238 SdGtkrllalltallralkkgsllliDEpEngLHPkllrrllell....k 283
                 S G ++ l+l+  +++++   +++++D++ + L+ k ++++ e l     
  EEA22083.1 696 SGGERQRLGLARTIAQRP---DIIILDDVFSALDKKTVKHIRERLfgpnG 742
                 566666666666677766...9******************9955535532 PP

  == domain 3  score: 7.4 bits;  conditional E-value: 0.0085
      AAA_21    3 vliGpNgsGKSnLLdaldll 22  
                  ++ G+ gsGKS+L+ +l  l
  EEA22083.1 1193 AICGRSGSGKSTLILTLLSL 1212
                  799***********999877 PP

  == domain 4  score: 13.6 bits;  conditional E-value: 0.00011
      AAA_21  224 lengdgqelparel..SdGtkrllalltallralkkg.sllliDEpEngLHPkllrrllell.k 283 
                   e ++g ++p++++  S G  +l+al+  +l a +++ +++l+DE  ++++ +  +++++l+ +
  EEA22083.1 1281 IETSGGLDTPLTDIslSAGEMQLFALARTILNAEQSPgGIVLFDEATSSIDVETETKIMRLIrE 1344
                  5778888999999988********************9***************888888888842 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.9   0.3   0.00017     0.071      14      42 ..     591     619 ..     581     621 .. 0.74
   2 !   18.4   0.1   3.3e-06    0.0014      13      46 ..    1180    1213 ..    1175    1219 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 0.00017
      AAA_29  14 ghtieidlkg.atlltGpsGsGKSTllDAi 42 
                 + ++++  kg  +++tG +GsGKS l+ A+
  EEA22083.1 591 DVSLKVL-KGdHVVITGGTGSGKSLLMKAL 619
                 4444554.4569************999776 PP

  == domain 2  score: 18.4 bits;  conditional E-value: 3.3e-06
      AAA_29   13 dghtieidlkgatlltGpsGsGKSTllDAiqalL 46  
                  dg  ++i++ + + + G+sGsGKSTl+  +  l+
  EEA22083.1 1180 DGINLTIHPGEKVAICGRSGSGKSTLILTLLSLM 1213
                  566788998889**************96555555 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.5   0.1   0.00025       0.1      95     134 ..     595     634 ..     569     638 .. 0.87
   2 !   14.4   0.0   6.3e-05     0.026      88     130 ..    1177    1220 ..    1158    1225 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00025
                  HHCTTSEEEEECSTTSSHHHHHHHHCTT-----S------ CS
  RsgA_GTPase  95 ellkdktsvlvGqSGvGKStLinallpelelktgevsekl 134
                  ++lk++ +v+ G +G GKS L++all+e e   g v+ ++
   EEA22083.1 595 KVLKGDHVVITGGTGSGKSLLMKALLGEVEFMAGTVRVSS 634
                  68999***********************999998888665 PP

  == domain 2  score: 14.4 bits;  conditional E-value: 6.3e-05
                   TTHHHHHHHCTT.SEEEEECSTTSSHHHHHHHHCTT-----S-- CS
  RsgA_GTPase   88 egleelkellkd.ktsvlvGqSGvGKStLinallpelelktgev 130 
                    +++ ++  ++  + ++++G SG GKStLi +ll+ +e + g +
   EEA22083.1 1177 WNIDGINLTIHPgEKVAICGRSGSGKSTLILTLLSLMENRKGTI 1220
                   55666666666668899****************99888777665 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.0   0.00083      0.34       6      28 ..     600     622 ..     597     674 .. 0.91
   2 !   13.2   0.1   0.00019     0.079       9      37 ..    1193    1221 ..    1189    1356 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00083
      AAA_22   6 gilvvtGesGtGKTtllrrlleq 28 
                  ++v+tG +G+GK++l++ ll +
  EEA22083.1 600 DHVVITGGTGSGKSLLMKALLGE 622
                 589***************99865 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 0.00019
      AAA_22    9 vvtGesGtGKTtllrrlleqldeeakaee 37  
                  +++G sG+GK+tl+ +ll+  ++++   +
  EEA22083.1 1193 AICGRSGSGKSTLILTLLSLMENRKGTIM 1221
                  79****************99887655444 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.6   0.4   0.00013     0.054      17      46 ..     595     622 ..     581     630 .. 0.82
   2 !   13.3   0.1   0.00016     0.067      25      59 ..    1191    1224 ..    1182    1250 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 0.00013
       DUF87  17 dlnklvtrHlAilgsTGsGKSntvavLlee 46 
                 ++  l   H+ i g TGsGKS +++ Ll e
  EEA22083.1 595 KV--LKGDHVVITGGTGSGKSLLMKALLGE 622
                 44..5568*******************977 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 0.00016
       DUF87   25 HlAilgsTGsGKSntvavLleellekkgatililD 59  
                   +Ai g++GsGKS+++  Ll+ +   +++ti i D
  EEA22083.1 1191 KVAICGRSGSGKSTLILTLLSLME-NRKGTIMIDD 1224
                  68******************8776.6666666655 PP

>> TrwB_AAD_bind  Type IV secretion-system coupling protein DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.5   0.2   0.00051      0.21      16      40 ..     600     624 ..     591     632 .. 0.89
   2 !   12.2   0.0   0.00015     0.062      17      90 ..    1191    1281 ..    1177    1285 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00051
  TrwB_AAD_bind  16 qhilivGttGsGKtqalekllrair 40 
                     h++i+G+tGsGK+  +++ll +++
     EEA22083.1 600 DHVVITGGTGSGKSLLMKALLGEVE 624
                    7********************8875 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 0.00015
  TrwB_AAD_bind   17 hilivGttGsGKtqalekllrairargdraivlDltGa.fvsrfyd............egkdillnPlDaRsa.....aWsvfaeikeksdf 90  
                     +++i G  GsGK++ +  ll  +++r+ ++++ D     +     +             g d++ +P+D + +     +Ws +++++ k+++
     EEA22083.1 1191 KVAICGRSGSGKSTLILTLLSLMENRKGTIMIDDIDISrLKPSLLRsrfhvisqdtyiHG-DTVRDPFDPKGTssndkIWSTLEDCSLKQKI 1281
                     689***************************999976331222222233444777666444.8888888876542222258888888877765 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.1     2e-05    0.0082     125     154 ..     595     624 ..     569     632 .. 0.82
   2 !    6.9   0.1    0.0068       2.8     131     163 ..    1191    1222 ..    1166    1229 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 2e-05
       T2SSE 125 avrerglilvsGgTgsGKttllyallkein 154
                  v +   ++++GgTgsGK+ l+ all e++
  EEA22083.1 595 KVLKGDHVVITGGTGSGKSLLMKALLGEVE 624
                 55566789******************9986 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0068
       T2SSE  131 lilvsGgTgsGKttllyallkeinksderivtv 163 
                   + + G  gsGK+tl+ +ll+ +++++  i+ +
  EEA22083.1 1191 KVAICGRSGSGKSTLILTLLSLMENRKGTIM-I 1222
                  56789*******************9966665.4 PP

>> SbcCD_C  Putative exonuclease SbcCD, C subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   0.0    0.0036       1.5      36      83 ..     685     732 ..     677     737 .. 0.80
   2 !   12.1   0.0   0.00042      0.17      33      89 ..    1283    1343 ..    1274    1344 .. 0.77

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0036
     SbcCD_C  36 GekqflaylalaaalaalyssaegrepalrlvfLDEAFsklDeesiat 83 
                 Ge+     ++l  + ++ ++ a++  +++++++LD+ Fs lD+++++ 
  EEA22083.1 685 GETIGSGGICLSGGERQRLGLARTIAQRPDIIILDDVFSALDKKTVKH 732
                 6666666677777777778887766789***************99876 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 0.00042
     SbcCD_C   33 lSGGekqflaylalaaalaalyssae...g.repalrlvfLDEAFsklDeesiatllelle 89  
                   SGG    l+ + l a+  +l+  a+   + +++  ++v++DEA s++D e+ +++++l++
  EEA22083.1 1283 TSGGLDTPLTDISLSAGEMQLFALARtilNaEQSPGGIVLFDEATSSIDVETETKIMRLIR 1343
                  5777777777777777777777777633323566689********************9987 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.7   0.1   0.00069      0.28      28      58 ..     594     624 ..     583     637 .. 0.79
   2 !    8.9   0.0    0.0024      0.96      27      61 ..    1183    1217 ..    1179    1229 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00069
       AAA_7  28 lllknkkpvllvGptGtGKtviikdllkkld 58 
                 l + ++ +v+++G tG+GK++++k ll +++
  EEA22083.1 594 LKVLKGDHVVITGGTGSGKSLLMKALLGEVE 624
                 5566889******************998876 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.0024
       AAA_7   27 elllknkkpvllvGptGtGKtviikdllkkldkek 61  
                  +l ++ + +v ++G +G+GK+++i +ll+ ++++k
  EEA22083.1 1183 NLTIHPGEKVAICGRSGSGKSTLILTLLSLMENRK 1217
                  567788899*****************999998665 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.3   0.1   0.00019     0.079      39      61 ..     596     621 ..     565     641 .. 0.78
   2 !   10.6   0.0   0.00064      0.26      39      60 ..    1188    1210 ..    1162    1214 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00019
                   -....SEEEE--TTSSHHHHHHHHHH CS
  FtsK_SpoIIIE  39 a...shllvaGatgsGKStalntLil 61 
                        h+++ G+tgsGKS  +++L+ 
    EEA22083.1 596 VlkgDHVVITGGTGSGKSLLMKALLG 621
                   23356****************99985 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00064
                    -..SEEEE--TTSSHHHHHHHHH CS
  FtsK_SpoIIIE   39 a.shllvaGatgsGKStalntLi 60  
                    +   + ++G++gsGKSt + tL+
    EEA22083.1 1188 PgEKVAICGRSGSGKSTLILTLL 1210
                    455799************99986 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.4   0.0   0.00074       0.3      21     144 ..     598     721 ..     586     735 .. 0.67
   2 !    8.4   0.1    0.0063       2.6      27      51 ..    1192    1216 ..    1185    1325 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00074
      AAA_16  21 sgrpelvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipy...salaqalareellrqlldeaesaeleawrekleeala........av 108
                 +g    v+++G  G+GKs l+++ll +     + f++g+ + +++ i y   s++++ +      +  +    +++ e+wr+k+++a a        ++
  EEA22083.1 598 KG--DHVVITGGTGSGKSLLMKALLGE-----VEFMAGTVRVSSARIGYcgqSIWLENALM-LDNAFRC----ASDSEEWRHKILDACAltellntsDS 684
                 45..479**************999964.....55788888888777777664454444411.2222222....33779999999999997777655422 PP

      AAA_16 109 pelagaea..........srllellkrllallsrderplvlvlDdl 144
                 +e                +r +  l+r +      +rp +++lDd+
  EEA22083.1 685 GET----IgsggiclsggERQRLGLARTI-----AQRPDIIILDDV 721
                 222....1334477777777777777777.....255678888885 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0063
      AAA_16   27 vllsGesGvGKsslvrellralekd 51  
                  v + G sG+GKs+l+ +ll  +e +
  EEA22083.1 1192 VAICGRSGSGKSTLILTLLSLMENR 1216
                  7899***********9999655555 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.4   0.2    0.0055       2.2       2      23 ..     602     623 ..     601     638 .. 0.81
   2 !   11.1   0.0   0.00078      0.32       1      21 [.    1191    1211 ..    1191    1228 .. 0.85

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0055
                 EEEEESTTSSHHHHHHHHHTST CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltgek 23 
                 v+i G + +GKS L++al+ge+
  EEA22083.1 602 VVITGGTGSGKSLLMKALLGEV 623
                 89*****************973 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00078
                  EEEEEESTTSSHHHHHHHHHT CS
    MMR_HSR1    1 evaivGrpNvGKStLinaltg 21  
                  +vai Gr+ +GKStLi +l+ 
  EEA22083.1 1191 KVAICGRSGSGKSTLILTLLS 1211
                  69**************99974 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.5   0.1    0.0031       1.3      22      39 ..     602     619 ..     589     621 .. 0.89
   2 !    8.4   0.2    0.0069       2.8      22      36 ..    1192    1206 ..    1180    1212 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.0031
      AAA_23  22 tlItGpNGaGKTTildAi 39 
                 ++ItG +G+GK+ ++ A+
  EEA22083.1 602 VVITGGTGSGKSLLMKAL 619
                 79*************998 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0069
      AAA_23   22 tlItGpNGaGKTTil 36  
                  ++I+G  G+GK+T++
  EEA22083.1 1192 VAICGRSGSGKSTLI 1206
                  48***********98 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.3     0.046        19       3      21 ..     602     620 ..     600     630 .. 0.87
   2 !   10.9   0.0   0.00061      0.25       4      37 ..    1193    1226 ..    1191    1243 .. 0.85

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.046
                 EEEEESTTCCHHHHHHHHH CS
        cobW   3 tvltGflGsGKTtLlnhll 21 
                 +v+tG  GsGK+ L+++ll
  EEA22083.1 602 VVITGGTGSGKSLLMKALL 620
                 79**************998 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00061
                  EEEESTTCCHHHHHHHHHCT--SS-EEEEESS-S CS
        cobW    4 vltGflGsGKTtLlnhllenraglklavivNefg 37  
                   ++G  GsGK+tL+ +ll+  +++k  +++ ++ 
  EEA22083.1 1193 AICGRSGSGKSTLILTLLSLMENRKGTIMIDDID 1226
                  68999*************9999999999999886 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   0.1     0.018       7.5      19      42 ..     596     619 ..     584     636 .. 0.80
   2 ?    6.6   0.0     0.014       5.8      21      74 ..    1188    1243 ..    1170    1254 .. 0.75
   3 ?   -0.5   0.0       2.1   8.5e+02      90     120 ..    1314    1345 ..    1308    1351 .. 0.85

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.018
                      CTSSS-EEEECSTTSSHHHHHHHH CS
  Sigma54_activat  19 aktdlsvlitGesGtGKellarai 42 
                      + +  +v+itG +G+GK+ll +a+
       EEA22083.1 596 VLKGDHVVITGGTGSGKSLLMKAL 619
                      555679*************99987 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.014
                       SSS-EEEECSTTSSHHHHHHHHHHHSTTTTS.-EE.EEETTTS-TTCHHHHHHEBS CS
  Sigma54_activat   21 tdlsvlitGesGtGKellaraiheaskrkek.pfv.avncaaipeelleseLFGhe 74  
                          +v i G sG+GK++l  ++ +  +++++  ++  ++++ ++++ll+s++  ++
       EEA22083.1 1188 PGEKVAICGRSGSGKSTLILTLLSLMENRKGtIMIdDIDISRLKPSLLRSRFHVIS 1243
                       557899**********9998888866555551444358999999999999886655 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 2.1
                       HHTTTSEEEEETG.GGS-HHHHHHHHHHHHHS CS
  Sigma54_activat   90 ekadgGtlfLDei.gelplelQekLlrvlqeg 120 
                       e++ gG++++De  +++++e+ +k++r++ e+
       EEA22083.1 1314 EQSPGGIVLFDEAtSSIDVETETKIMRLIRER 1345
                       78889******972579***********9987 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.4     0.029        12       1      45 [.     601     637 ..     601     723 .. 0.83
   2 !    8.6   0.0    0.0041       1.7       1      26 [.    1191    1216 ..    1191    1243 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.029
                 EEEEE--TTSSHHHHHHHHHHHH...GGGEEEEEEEEE------- CS
    NTPase_1   1 kvfiTGppGvGKtTlvkkvlellkssgvkvgGfyteevreggrri 45 
                 +v+iTG  G+GK+ l+k +l +++        f++  vr    ri
  EEA22083.1 601 HVVITGGTGSGKSLLMKALLGEVE--------FMAGTVRVSSARI 637
                 79**************99998884........5555555555555 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.0041
                  EEEEE--TTSSHHHHHHHHHHHH... CS
    NTPase_1    1 kvfiTGppGvGKtTlvkkvlellkss 26  
                  kv+i G++G+GK+Tl+  +l+l++++
  EEA22083.1 1191 KVAICGRSGSGKSTLILTLLSLMENR 1216
                  589**************999998765 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.1     0.012       4.7      18      49 ..     601     632 ..     589     637 .. 0.85
   2 !    7.4   0.0    0.0057       2.3      20      59 ..    1193    1232 ..    1188    1246 .. 0.88

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.012
  Zeta_toxin  18 lillgGqpGAGKselaellkdelerqgnvvrl 49 
                  +++ G++G+GKs l+++l  e+e   + vr+
  EEA22083.1 601 HVVITGGTGSGKSLLMKALLGEVEFMAGTVRV 632
                 5899***************9999866677776 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0057
  Zeta_toxin   20 llgGqpGAGKselaellkdelerqgnvvrldpDdlRelhP 59  
                   + G +G+GKs+l+  l   +e++++ + +d  d+ +l P
  EEA22083.1 1193 AICGRSGSGKSTLILTLLSLMENRKGTIMIDDIDISRLKP 1232
                  5789************************999877766666 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.2      0.47   1.9e+02       1      20 [.     601     620 ..     601     633 .. 0.88
   2 ?    1.5   0.0      0.65   2.6e+02      52      78 ..     699     725 ..     674     735 .. 0.80
   3 !    7.9   0.0    0.0073         3       2      31 ..    1192    1221 ..    1191    1246 .. 0.84
   4 ?   -1.3   0.0         5     2e+03      80     105 ..    1353    1378 ..    1348    1386 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.47
                 EEEEE--SSSSHHHHHHHGG CS
       AAA_5   1 dvlLvGppGtgKselaerla 20 
                 +v++ G +G+gKs l++ l+
  EEA22083.1 601 HVVITGGTGSGKSLLMKALL 620
                 799************99876 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.65
                 .....--------G-SEEEEESGGG-- CS
       AAA_5  52 tslvdsplvraaregeilvlDEverae 78 
                 ++ + + + + a++++i++lD+v+ a 
  EEA22083.1 699 ERQRLGLARTIAQRPDIIILDDVFSAL 725
                 5555666778899**********9886 PP

  == domain 3  score: 7.9 bits;  conditional E-value: 0.0073
                  EEEE--SSSSHHHHHHHGGGGB.S--EEEEE CS
       AAA_5    2 vlLvGppGtgKselaerlaaal.nreveyvq 31  
                  v + G +G+gKs+l+  l++++ nr   +++
  EEA22083.1 1192 VAICGRSGSGKSTLILTLLSLMeNR-KGTIM 1221
                  5678******************555.44444 PP

  == domain 4  score: -1.3 bits;  conditional E-value: 5
                  HHHHHHHHHHHSSEEE..-SSSEEE- CS
       AAA_5   80 evlnsLlslleerrllleeggelvka 105 
                  ++l +L + le +r+l+++ g++++ 
  EEA22083.1 1353 SILHRLETALEYDRVLVMDQGRVIHS 1378
                  7899999************9999875 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.2   0.2    0.0045       1.8      20      40 ..     601     621 ..     592     636 .. 0.77
   2 ?    5.7   0.0     0.026        11      21      49 ..    1192    1220 ..    1183    1223 .. 0.84

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0045
      AAA_30  20 vavltGpAGtGKttalkalre 40 
                  +v+tG+ G+GK+ ++kal  
  EEA22083.1 601 HVVITGGTGSGKSLLMKALLG 621
                 589**************9854 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.026
      AAA_30   21 avltGpAGtGKttalkalreaweaaggrv 49  
                  +++ G+ G+GK+t++ +l  ++e+++g++
  EEA22083.1 1192 VAICGRSGSGKSTLILTLLSLMENRKGTI 1220
                  6789**************99999997776 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.2   0.1    0.0031       1.3      50      77 ..     596     623 ..     585     633 .. 0.87
   2 ?    5.5   0.0      0.02       8.1      51      82 ..    1187    1220 ..    1182    1246 .. 0.77

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0031
      DUF815  50 glpannvLLwGarGtGKSslvkallney 77 
                  l+  +v+++G  G+GKS l+kall e+
  EEA22083.1 596 VLKGDHVVITGGTGSGKSLLMKALLGEV 623
                 56789*******************9886 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.02
      DUF815   51 lpannvLLwGarGtGKSslvkallneyaeeg..L 82  
                  +p ++v + G  G+GKS+l+ +ll+ +++++  +
  EEA22083.1 1187 HPGEKVAICGRSGSGKSTLILTLLSLMENRKgtI 1220
                  57788999**************999888776442 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   0.0     0.012       5.1       1      23 [.     602     624 ..     602     661 .. 0.83
   2 ?    6.8   0.0     0.022       8.9       2      24 ..    1193    1215 ..    1192    1231 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.012
  RNA_helicase   1 iwlyGpsgeGKStlakeLakall 23 
                   ++++G +g GKS+l+k L  +++
    EEA22083.1 602 VVITGGTGSGKSLLMKALLGEVE 624
                   689**************987776 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.022
  RNA_helicase    2 wlyGpsgeGKStlakeLakallk 24  
                     ++G+sg GKStl+ +L + +++
    EEA22083.1 1193 AICGRSGSGKSTLILTLLSLMEN 1215
                    69***********9998776664 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.0     0.058        24       1      37 [.     602     650 ..     602     702 .. 0.71
   2 !    8.6   0.0    0.0063       2.6       1      25 [.    1192    1223 ..    1192    1274 .. 0.72

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.058
      AAA_18   1 IlltGtpGvGKttlakeLskrlgf............gvnlrdvakengl 37 
                 +++tG  G+GK+ l k+L  + +f            g+  ++++ en l
  EEA22083.1 602 VVITGGTGSGKSLLMKALLGEVEFmagtvrvssariGYCGQSIWLENAL 650
                 79****************4443445554544444445555555555555 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.0063
      AAA_18    1 IlltGtpGvGKttlakeLskrlgf.......g 25  
                  ++++G +G+GK+tl   L +++++        
  EEA22083.1 1192 VAICGRSGSGKSTLILTLLSLMENrkgtimiD 1223
                  78************999977764446434340 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.1     0.086        35       2      30 ..     602     634 ..     602     769 .. 0.83
   2 !    8.4   0.0    0.0056       2.3       2      20 ..    1192    1210 ..    1192    1255 .. 0.77

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.086
      AAA_33   2 vllvGlpGsGKstlaerllkklg....avllss 30 
                 v++ G  GsGKs l + ll +      +v++ss
  EEA22083.1 602 VVITGGTGSGKSLLMKALLGEVEfmagTVRVSS 634
                 5678999***********998887766666666 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0056
      AAA_33    2 vllvGlpGsGKstlaerll 20  
                  v ++G +GsGKstl+  ll
  EEA22083.1 1192 VAICGRSGSGKSTLILTLL 1210
                  568***********98874 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.1       1.3   5.3e+02      32      50 ..     598     616 ..     588     623 .. 0.84
   2 !   12.0   0.0   0.00028      0.11      13      54 ..    1166    1210 ..    1154    1217 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 1.3
      AAA_25  32 agelallaGapgtGKttla 50 
                 +g+ ++++G +g+GK+ l 
  EEA22083.1 598 KGDHVVITGGTGSGKSLLM 616
                 6888999*********997 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 0.00028
      AAA_25   13 adlaapppprrwlvkg...llpagelallaGapgtGKttlaldla 54  
                  + +a++ ++ +w ++g    +  ge ++++G++g+GK+tl l l 
  EEA22083.1 1166 SSYASAVEQSSWNIDGinlTIHPGEKVAICGRSGSGKSTLILTLL 1210
                  44677889999****98887999*****************99875 PP

>> AAA_10  AAA-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.1    0.0011      0.44      20      48 ..     598     626 ..     587     636 .. 0.82
   2 ?    2.6   0.0      0.12        50      23      54 ..    1191    1222 ..    1181    1231 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0011
      AAA_10  20 nasasliiGdlGnGKSvlakllvlyisll 48 
                 +  +++i+G++G GKS+l+k l   + ++
  EEA22083.1 598 KGDHVVITGGTGSGKSLLMKALLGEVEFM 626
                 55789***************998777665 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.12
      AAA_10   23 asliiGdlGnGKSvlakllvlyisllggkali 54  
                  +++i G  G GKS l+ +l   +  ++g ++i
  EEA22083.1 1191 KVAICGRSGSGKSTLILTLLSLMENRKGTIMI 1222
                  569***************99999988888776 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.3    0.0025         1       2      20 ..     602     620 ..     601     640 .. 0.87
   2 ?    4.0   0.1      0.14        55       1      20 [.    1191    1210 ..    1191    1225 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0025
      AAA_28   2 ivitGgestGKTtlleaLa 20 
                 +vitGg ++GK+ l++aL 
  EEA22083.1 602 VVITGGTGSGKSLLMKALL 620
                 8***************995 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.14
      AAA_28    1 kivitGgestGKTtlleaLa 20  
                  k++i G +++GK+tl+  L 
  EEA22083.1 1191 KVAICGRSGSGKSTLILTLL 1210
                  799************97664 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.1      0.23        93       4      22 ..     601     619 ..     598     645 .. 0.83
   2 ?    9.1   0.0    0.0025         1       4      29 ..    1191    1222 ..    1189    1230 .. 0.79

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.23
      AAA_24   4 kiliyGpsgiGKTtlakel 22 
                  ++i+G  g+GK+ l+k l
  EEA22083.1 601 HVVITGGTGSGKSLLMKAL 619
                 589*************988 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.0025
      AAA_24    4 kiliyGpsgiGKTtlakel......gpkplfi 29  
                  k++i G sg+GK+tl+++l       + +++i
  EEA22083.1 1191 KVAICGRSGSGKSTLILTLlslmenRKGTIMI 1222
                  89***************996666554445554 PP

>> Pox_A32  Poxvirus A32 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   0.3     0.027        11      16      35 ..     602     621 ..     594     625 .. 0.88
   2 ?    7.1   0.1    0.0078       3.2      15      38 ..    1191    1214 ..    1183    1222 .. 0.87

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.027
     Pox_A32  16 lalvGgsGsGktvyLlsLlr 35 
                 ++++Gg+GsGk + +++Ll 
  EEA22083.1 602 VVITGGTGSGKSLLMKALLG 621
                 79**************9985 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0078
     Pox_A32   15 rlalvGgsGsGktvyLlsLlrtlv 38  
                  ++a+ G sGsGk + +l Ll+ + 
  EEA22083.1 1191 KVAICGRSGSGKSTLILTLLSLME 1214
                  689****************98775 PP

>> MobB  Molybdopterin guanine dinucleotide synthesis protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.1      0.72   2.9e+02       2      24 ..     602     624 ..     601     634 .. 0.82
   2 ?   10.3   0.0    0.0012      0.48       2      29 ..    1192    1219 ..    1191    1249 .. 0.90

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.72
        MobB   2 lgivgksgsGKTtLleklipelk 24 
                 + i+g  gsGK  L++ l+ e++
  EEA22083.1 602 VVITGGTGSGKSLLMKALLGEVE 624
                 578999************98764 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.0012
        MobB    2 lgivgksgsGKTtLleklipelkarglr 29  
                  ++i+g+sgsGK tL+  l++ +++r+ +
  EEA22083.1 1192 VAICGRSGSGKSTLILTLLSLMENRKGT 1219
                  689*******************998755 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   0.2     0.015       6.2       8      32 ..     597     621 ..     592     639 .. 0.83
   2 ?    4.1   0.0      0.13        54       9      39 ..    1188    1218 ..    1182    1226 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.015
      AAA_19   8 lkekvllvtaGpGtGKTrvlkhiva 32 
                 lk +++++t+G G+GK+ ++k+ + 
  EEA22083.1 597 LKGDHVVITGGTGSGKSLLMKALLG 621
                 67899************99988765 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.13
      AAA_19    9 kekvllvtaGpGtGKTrvlkhivallvelgg 39  
                  + + +++ +  G+GK++++ + ++l+++++g
  EEA22083.1 1188 PGEKVAICGRSGSGKSTLILTLLSLMENRKG 1218
                  6678999***************999988775 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   0.2     0.015       6.3       2      21 ..     601     620 ..     600     624 .. 0.88
   2 ?   -2.2   0.0       8.5   3.5e+03     112     134 ..    1016    1038 ..    1003    1056 .. 0.78
   3 ?    7.1   0.1     0.012       4.8       3      27 ..    1192    1216 ..    1190    1220 .. 0.86

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.015
                 CEEEEC-TTTCHHHHHHHHH CS
       NACHT   2 lvilqGeaGsGKTtLlqkla 21 
                  v+++G  GsGK+ L++ l 
  EEA22083.1 601 HVVITGGTGSGKSLLMKALL 620
                 589*************9886 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 8.5
                  HHCTTTTT--EEEEEEECCCHHH CS
       NACHT  112 lirkkllpeasllltvrpralrd 134 
                   ++ kl+ ++  l+t+r  +++ 
  EEA22083.1 1016 SLQTKLMETCAGLVTIRAHQWQS 1038
                  678899999999****9999965 PP

  == domain 3  score: 7.1 bits;  conditional E-value: 0.012
                  EEEEC-TTTCHHHHHHHHHHHHCTS CS
       NACHT    3 vilqGeaGsGKTtLlqklalawaeg 27  
                  v++ G++GsGK+tL+  l +++  +
  EEA22083.1 1192 VAICGRSGSGKSTLILTLLSLMENR 1216
                  7899***********9999887765 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.1     0.026        10      46      67 ..     598     619 ..     587     638 .. 0.86
   2 ?    4.4   0.0     0.067        27      45      66 ..    1187    1208 ..    1161    1222 .. 0.87

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.026
   IstB_IS21  46 kkenivllGpsGvGKshlaial 67 
                 k + +v++G++G GKs l  al
  EEA22083.1 598 KGDHVVITGGTGSGKSLLMKAL 619
                 56889*************9997 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.067
   IstB_IS21   45 ekkenivllGpsGvGKshlaia 66  
                  +  e ++++G sG GKs l  +
  EEA22083.1 1187 HPGEKVAICGRSGSGKSTLILT 1208
                  56789************99765 PP

>> DUF2075  Uncharacterized conserved protein (DUF2075)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.1       7.8   3.2e+03      15      75 ..     376     440 ..     376     451 .. 0.74
   2 ?    9.3   0.2    0.0014      0.59       4      25 ..     602     623 ..     600     639 .. 0.86
   3 ?    2.0   0.0      0.24        98       5      25 ..    1193    1213 ..    1190    1231 .. 0.84
   4 ?   -2.9   0.0       7.4     3e+03      80     102 ..    1309    1331 ..    1295    1383 .. 0.60

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 7.8
     DUF2075  15 tvvllnllael.....eddeeertavylsvNhplvlvlrealakkeekkkkkeafeklssfinnls 75 
                 tv++l+l+ ++      ++  +++++ +   ++ +++ r+ l++ +   k + + +++ss i++l+
  EEA22083.1 376 TVLGLALVSTAistyiGKSTGKQQQKWMAATEKRIATTRKMLSSLK-AIKTTGSEQRVSSTIQTLR 440
                 6777777776666665667777788888888888888888887766.8888888899999999877 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.0014
     DUF2075   4 vlVtGvaGtGKtvvllnllael 25 
                 v++tG++G+GK++++ +ll e+
  EEA22083.1 602 VVITGGTGSGKSLLMKALLGEV 623
                 79***************99998 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.24
     DUF2075    5 lVtGvaGtGKtvvllnllael 25  
                   + G++G+GK+ + l+ll  +
  EEA22083.1 1193 AICGRSGSGKSTLILTLLSLM 1213
                  588************999876 PP

  == domain 4  score: -2.9 bits;  conditional E-value: 7.4
     DUF2075   80 aeekkeepkedvvivDEAhrllt 102 
                   + ++e+ +  +v++DEA    +
  EEA22083.1 1309 TILNAEQSPGGIVLFDEATSSID 1331
                  55667888889999***987777 PP

>> Viral_helicase1  Viral (Superfamily 1) RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.2      0.13        54       2      22 ..     603     623 ..     602     643 .. 0.80
   2 ?    6.6   0.0     0.014       5.8       5      35 ..    1196    1222 ..    1192    1242 .. 0.76

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.13
  Viral_helicase1   2 vvhGvpGcGKStlirkllrts 22 
                      v+ G  G+GKS l + ll + 
       EEA22083.1 603 VITGGTGSGKSLLMKALLGEV 623
                      89*************999884 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.014
  Viral_helicase1    5 GvpGcGKStlirkllrtsliltvnrptaell 35  
                       G  G+GKStli +ll+      +nr+ ++++
       EEA22083.1 1196 GRSGSGKSTLILTLLSL----MENRKGTIMI 1222
                       677************87....4566655555 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.1     0.025        10      11      30 ..     596     615 ..     590     624 .. 0.86
   2 ?    4.1   0.1     0.083        34      11      33 ..    1186    1208 ..    1180    1222 .. 0.77

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.025
                 HHTTCEEEEEESTTSSHHHH CS
                 xxxxxxxxxxxxxxxxxxxx RF
        DEAD  11 ilgggdvlvaaeTGsGKTla 30 
                 +l+g++v++ + TGsGK+l 
  EEA22083.1 596 VLKGDHVVITGGTGSGKSLL 615
                 6899*************986 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.083
                  HHTTCEEEEEESTTSSHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   11 ilgggdvlvaaeTGsGKTlafli 33  
                  i  g++v ++++ GsGK++  l 
  EEA22083.1 1186 IHPGEKVAICGRSGSGKSTLILT 1208
                  56899************998544 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.1      0.12        48      22      41 ..     601     620 ..     594     630 .. 0.86
   2 ?   -1.5   0.0       4.8   1.9e+03     121     134 ..     715     728 ..     705     759 .. 0.75
   3 ?    4.9   0.0     0.053        21      23      47 ..    1192    1216 ..    1184    1251 .. 0.82

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.12
    ATPase_2  22 iyfiYGpegsGKtaLlkeii 41 
                  ++i+G  gsGK+ L+k ++
  EEA22083.1 601 HVVITGGTGSGKSLLMKALL 620
                 589*************9876 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 4.8
    ATPase_2 121 iiiiDelqklidlg 134
                 iii+D+++ + d +
  EEA22083.1 715 IIILDDVFSALDKK 728
                 99******998654 PP

  == domain 3  score: 4.9 bits;  conditional E-value: 0.053
    ATPase_2   23 yfiYGpegsGKtaLlkeiienledk 47  
                  + i G+ gsGK++L+  +++  e+ 
  EEA22083.1 1192 VAICGRSGSGKSTLILTLLSLMENR 1216
                  6799************999888653 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.1     0.033        13      22      43 ..     599     620 ..     590     637 .. 0.85
   2 ?    3.7   0.0     0.086        35      21      54 ..    1188    1221 ..    1172    1246 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.033
  Mg_chelatase  22 gHnlllvGppGsGKtmlakrlp 43 
                   g +++++G  GsGK++l k+l 
    EEA22083.1 599 GDHVVITGGTGSGKSLLMKALL 620
                   3468899**********99885 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.086
  Mg_chelatase   21 GgHnlllvGppGsGKtmlakrlpsllpplseeea 54  
                     g ++ ++G +GsGK+ l+  l sl+ + + + +
    EEA22083.1 1188 PGEKVAICGRSGSGKSTLILTLLSLMENRKGTIM 1221
                    5667899*************99999987666555 PP

>> ATP-synt_ab  ATP synthase alpha/beta family, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0     0.086        35       7      37 ..     592     622 ..     589     813 .. 0.87
   2 ?    5.3   0.1     0.034        14       9      41 ..    1184    1216 ..    1178    1228 .. 0.77

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.086
                  HHS-EBTT-EEEEEESTTSSHHHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab   7 alfpivqGqrtlipgafgvGktvisqslskq 37 
                  + + + +G  ++i g+ g Gk+ ++++l+ +
   EEA22083.1 592 VSLKVLKGDHVVITGGTGSGKSLLMKALLGE 622
                  5567899******************998765 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.034
                   S-EBTT-EEEEEESTTSSHHHHHHHHHHHSSTS CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab    9 fpivqGqrtlipgafgvGktvisqslskqsnsd 41  
                   ++i  G++++i g +g Gk++++ +l+  ++++
   EEA22083.1 1184 LTIHPGEKVAICGRSGSGKSTLILTLLSLMENR 1216
                   58899****************997666554444 PP

>> CbiA  CobQ/CobB/MinD/ParA nucleotide binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   0.00046      0.19       5      43 ..    1195    1233 ..    1191    1361 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00046
                  ESSTTSSHHHHHHHHHHHHHHTT--EEEEE.EEESSCCCC CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxx RF
        CbiA    5 stkGGvGKTtlaanLaralarrglrVllvD.aDpqannla 43  
                   + +G+GK+tl ++L+ ++ + ++ ++++D  D  +   +
  EEA22083.1 1195 CGRSGSGKSTLILTLLSLMEN-RKGTIMIDdIDISRLKPS 1233
                  578**************9999.777777774666655444 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.4     0.014       5.8       2      41 ..     603     642 ..     602     748 .. 0.75
   2 ?    1.6   0.1      0.87   3.6e+02       4      23 ..    1195    1214 ..    1192    1356 .. 0.49

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.014
                 EEESSTTSSHHHHHHHHHHHHTHEE..EEEETTTCSSSSTTH CS
         AAA   2 llyGppGtGKTllakavakelgvef..leisgsellskyvge 41 
                 +++G  G GK+ll+ka+  e+++    +++s +++   y g+
  EEA22083.1 603 VITGGTGSGKSLLMKALLGEVEFMAgtVRVSSARIG--YCGQ 642
                 78999***************8755411444444433..4433 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.87
                  ESSTTSSHHHHHHHHHHHHT CS
         AAA    4 yGppGtGKTllakavakelg 23  
                  +G  G GK++l+  + + ++
  EEA22083.1 1195 CGRSGSGKSTLILTLLSLME 1214
                  66677777777666666553 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.1     0.035        14      18      37 ..     598     617 ..     591     623 .. 0.87
   2 ?   -2.7   0.0       7.4     3e+03     123     165 ..     716     758 ..     709     771 .. 0.82
   3 ?   -3.1   0.1       9.9     4e+03      99     143 ..     790     834 ..     751     837 .. 0.77
   4 ?    3.5   0.1     0.093        38      17      38 ..    1187    1208 ..    1178    1222 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.035
      ATPase  18 egrvvlitGepGtGKtifal 37 
                 +g  v itG++G+GK+++ +
  EEA22083.1 598 KGDHVVITGGTGSGKSLLMK 617
                 678899***********965 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 7.4
      ATPase 123 vviDsitglayeekeavaReilrqlvrvlkklgvTailvseks 165
                 +++D + +   +++ + +Re l+     l+ l+vT i +++ +
  EEA22083.1 716 IILDDVFSALDKKTVKHIRERLFGPNGLLRLLQVTIIETTQDQ 758
                 78888877768899999******99999999999999998854 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 9.9
      ATPase  99 kdkedleelieelaeaikeikakrvviDsitglayeekeavaRei 143
                 ++k d+e+  + +++ i+  + k   iDs +  ++ ++  v R++
  EEA22083.1 790 SSKGDIEAGETVITNTINVRQTKPARIDSSEEASRVKDRTVYRTY 834
                 678889999999999999999999999998888777777777776 PP

  == domain 4  score: 3.5 bits;  conditional E-value: 0.093
      ATPase   17 pegrvvlitGepGtGKtifalq 38  
                    g+ v i+G +G+GK+++ l+
  EEA22083.1 1187 HPGEKVAICGRSGSGKSTLILT 1208
                  567889***********98765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1400 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       807  (0.0450109); expected 358.6 (0.02)
Passed bias filter:                      502  (0.0279993); expected 358.6 (0.02)
Passed Vit filter:                        92  (0.00513135); expected 17.9 (0.001)
Passed Fwd filter:                        48  (0.00267723); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              44  [number of targets reported over threshold]
# CPU time: 1.10u 0.32s 00:00:01.42 Elapsed: 00:00:00.50
# Mc/sec: 8438.30
//
Query:       EEA22084.1  [L=612]
Description: pogo transposable element, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.8e-23   82.0   0.0    7.7e-23   81.0   0.0    1.6  1  DDE_1         DDE superfamily endonuclease
    8.5e-09   35.3   0.3    3.1e-08   33.5   0.3    2.0  1  HTH_Tnp_Tc5   Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
      0.024   14.7   0.1       0.49   10.6   0.0    2.6  3  Pcc1          Transcription factor Pcc1
       0.21   10.5   1.1       0.32    9.9   1.1    1.2  1  Amidase       Amidase


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.0   0.0   1.7e-26   7.7e-23       2     175 .]     193     368 ..     192     368 .. 0.89

  Alignments for each domain:
  == domain 1  score: 81.0 bits;  conditional E-value: 1.7e-26
       DDE_1   2 erltvllcanaagsekLkplvigkak..sprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrleaekrk..ilLlldssrshetvel.le 94 
                 +++ ++++++ a++  + p +i+ ak  +++ ++    ++++  + +  ++ +w+ ++++ +WL +vfdk ++++ ++   lL+ld+++sh t+ + + 
  EEA22084.1 193 REWITTIGCICANGTAISPALIYMAKsgNLQDSWLQDFDAEQHRCFFATSESGWTNNEVGFAWLvNVFDKETKSQASRgwRLLILDGHGSHVTMRFiEY 291
                 678999****************9665226888999999***********************************666652267**************999 PP

       DDE_1  95 selqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                 ++++ i l+++Pa+s+++lqP d+ ++s+l + Y +ql + +++  +        lt +d+++   ++w+  +++e+i saf
  EEA22084.1 292 CDKNRILLAIFPAHSTHTLQPPDVAIFSPLSTAYTEQL-RRFINDCQGFTR----LTKRDFFRLFWASWEaTFTSENILSAF 368
                 **********************************8765.556666655555....9**************99******9987 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.5   0.3   6.8e-12   3.1e-08       2      60 ..      59     108 ..      58     115 .. 0.91

  Alignments for each domain:
  == domain 1  score: 33.5 bits;  conditional E-value: 6.8e-12
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh 60 
                  +e+ + L++Wi+ql+erg p+t++++ + A+e+         + + ++k+W  r++k h
   EEA22084.1  59 KEQSRTLIKWINQLTERGLPPTNSMLENFAREI---------SGKEPGKNWASRWLKAH 108
                  68999****************************.........67889**********99 PP

>> Pcc1  Transcription factor Pcc1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00011      0.49      12      50 ..       5      43 ..       1      59 [. 0.88
   2 ?    0.7   0.0      0.13   5.7e+02      49      66 ..     405     422 ..     402     423 .. 0.91
   3 ?   -2.8   0.1       1.6     7e+03      12      36 ..     547     574 ..     544     599 .. 0.57

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00011
                HHHHHHHHHHHHHCHC-TTECEEEEEEETTEEEEEEEES CS
        Pcc1 12 rlAsialrtLqvDkelsplavkrslslegnvLqveykAt 50
                +lA  alr+L++D++++ + v r++ ++++ L  +++  
  EEA22084.1  5 ELALEALRSLRPDEKPNISLVARTYGVNQSNLSKRFRGV 43
                78888********9999888***********99998875 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.13
                 ESSHHHHHHHHHHHHHHH CS
        Pcc1  49 AttnrmLRvavngflesl 66 
                 A++ r LR  v+g++e+l
  EEA22084.1 405 AEDWRRLRKLVQGVFEDL 422
                 9999************98 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 1.6
                 HHHHHHHHHHHHH..CHC-TTE.CEEEE CS
        Pcc1  12 rlAsialrtLqvD..kelspla.vkrsl 36 
                 +lA+ a   Lq D  + +s ++  k+++
  EEA22084.1 547 ELAKLAHLQLQNDvlATPSAPKrAKKQV 574
                 6777777778877553333333333333 PP

>> Amidase  Amidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   1.1   7.3e-05      0.32     321     396 ..     501     580 ..     476     603 .. 0.71

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 7.3e-05
                 CCHHHHCCS-HHHHHHHHHHHHHCSCCCCCCCHHHHHHHHH.HHHHHHHHHCCC...BSEEEEESSSSS--BCCCCCHHH CS
     Amidase 321 lpksraellgeevkrrielgnyalsaeasskyylkaqkvrr.llrrefakafee...lDvllsPtaptpaprlgekdkti 396
                  ++  +++l+++ k + +    ++ +e++++ +++a++ +r   ++e+ak+ +     Dvl++P+ap+ a+++  k+ ++
  EEA22084.1 501 QAAQEQAQLTKQAKEQEKAERAQIRQEKQEQRLQEATEKQRlKDEQELAKLAHLqlqNDVLATPSAPKRAKKQVSKQVKV 580
                 3445567777777777777777777887777777777777656777777765557779*************998887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (612 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2806  (0.156506); expected 358.6 (0.02)
Passed bias filter:                      893  (0.0498076); expected 358.6 (0.02)
Passed Vit filter:                       159  (0.00886831); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.84u 0.33s 00:00:01.17 Elapsed: 00:00:00.49
# Mc/sec: 3720.72
//
Query:       EEA22085.1  [L=781]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.2e-06   25.5   0.0    1.3e-05   24.8   0.0    1.3  1  Peptidase_S41    Peptidase family S41
     0.0021   17.9   0.1      0.004   16.9   0.1    1.4  1  Methyltransf_31  Methyltransferase domain
      0.007   17.1   0.0      0.017   15.8   0.0    1.6  1  Methyltransf_25  Methyltransferase domain
  ------ inclusion threshold ------
       0.05   12.9   0.0      0.087   12.1   0.0    1.3  1  CMAS             Mycolic acid cyclopropane synthetase
      0.053   12.7   0.0       0.31   10.2   0.0    2.0  2  Methyltransf_3   O-methyltransferase
       0.21   10.9   0.0       0.46    9.8   0.0    1.5  1  Ubie_methyltran  ubiE/COQ5 methyltransferase family


Domain annotation for each model (and alignments):
>> Peptidase_S41  Peptidase family S41
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.8   0.0   4.5e-09   1.3e-05       1      66 [.     367     443 ..     367     488 .. 0.89

  Alignments for each domain:
  == domain 1  score: 24.8 bits;  conditional E-value: 4.5e-09
                    EEEEEEES-BCC...........THHHHHHHHHHHHHHTTSSEEEEE-TTB-EBEHHHHHHHHHCCSSSSEEEEEEC CS
  Peptidase_S41   1 kiGyiripsfse...........ktkeelakalkelkkknvkglilDlRnNgGGlldeavelaslflddglivstrg 66 
                    +++++++p+f++           + +e  a ++++  ++    +i+D+++NgGG l + ++las f++d++i +t +
     EEA22085.1 367 DVAVLQLPTFQStkldtkspnvtTISETAAIFIQRAVSDRKIRMIVDVSSNGGGDLIQGFRLASIFFPDKPIYTTTR 443
                    689*******66899*99999987788888888888889999*****************************987754 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.1   1.3e-06     0.004       3      35 ..     736     768 ..     734     771 .. 0.90

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 1.3e-06
  Methyltransf_31   3 kglrvlDlGCGtGeltfelaeelgpkaevvGiD 35 
                       g ++lD+GCG+Ge +++la  + ++++++ +D
       EEA22085.1 736 AGQHLLDIGCGQGESSLALALAVSSQGHITALD 768
                      67789***************99999*****999 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   5.6e-06     0.017       2      31 ..     741     771 ..     740     774 .. 0.91

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 5.6e-06
                      EEET-TTSHHHHHHHCTS.TSSEEEEEESSH CS
  Methyltransf_25   2 LdlGcGtGrltlalakrl.gkakvtgvDise 31 
                      Ld+GcG+G+ +lala ++ +++++t++D+++
       EEA22085.1 741 LDIGCGQGESSLALALAVsSQGHITALDPAQ 771
                      9**************999659*******975 PP

>> CMAS  Mycolic acid cyclopropane synthetase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   2.9e-05     0.087      54      77 ..     728     751 ..     720     762 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 2.9e-05
                 HHTTTT--TT-EEEEES-TTSHHH CS
        CMAS  54 ileklelkpGmtlLdiGcGWGslv 77 
                 i++  ++++G++lLdiGcG G+  
  EEA22085.1 728 IVDTWSIQAGQHLLDIGCGQGESS 751
                 6788899*************9865 PP

>> Methyltransf_3  O-methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0       0.2   5.9e+02      85     106 ..     392     413 ..     371     433 .. 0.82
   2 ?   10.2   0.0    0.0001      0.31      45      82 ..     734     771 ..     720     776 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.2
                     HHHHHHHHHHTT-GGGEEEEES CS
  Methyltransf_3  85 yeialkfiqkagvaekielieg 106
                      e a  fiq+a  ++ki +i+ 
      EEA22085.1 392 SETAAIFIQRAVSDRKIRMIVD 413
                     466788***********99875 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.0001
                     HHT--EEEEE--TTSHHHHHHHTTS-TT-EEEEEES-H CS
  Methyltransf_3  45 lvnakrvleiGvftGyslLatalalPeDGkilaididr 82 
                     +   ++ l+iG  +G s La+ala+   G+i+a+d  +
      EEA22085.1 734 IQAGQHLLDIGCGQGESSLALALAVSSQGHITALDPAQ 771
                     56667899**************************9654 PP

>> Ubie_methyltran  ubiE/COQ5 methyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0   0.00015      0.46      38      79 ..     727     768 ..     717     772 .. 0.88

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00015
                      HHHHH--S--TTEEEEES-TT-HHHHHHHHHHHHHHEEEEEE CS
  Ubie_methyltran  38 fveklvavkrgakvlDvagGtgDlafklsdsvgekgkvvvlD 79 
                       + ++ + + g+++lD+ +G g+ +++l+ +v ++g+++ lD
       EEA22085.1 727 TIVDTWSIQAGQHLLDIGCGQGESSLALALAVSSQGHITALD 768
                      5677788899****************************9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (781 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       368  (0.0205254); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.48
# Mc/sec: 4913.24
//
Query:       EEA22086.1  [L=114]
Description: hypothetical protein PMAA_058660 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (114 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       364  (0.0203023); expected 358.6 (0.02)
Passed bias filter:                      263  (0.014669); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 825.07
//
Query:       EEA22087.1  [L=243]
Description: hypothetical protein PMAA_058670 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.013   15.8   1.1        1.2    9.6   0.3    2.4  2  REV1_C           DNA repair protein REV1 C-terminal domain
      0.056   13.3   1.1       0.19   11.5   0.3    1.9  2  Sulfotransfer_4  Sulfotransferase domain


Domain annotation for each model (and alignments):
>> REV1_C  DNA repair protein REV1 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.0    0.0052        46      62      82 ..      17      37 ..       5      39 .. 0.86
   2 ?    9.6   0.3   0.00013       1.2      16      82 ..      57     121 ..      49     131 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.0052
      REV1_C 62 eeeageaWekafrevkeavqe 82
                ++ ++ +W++a+ ++ke+v++
  EEA22087.1 17 ADPVTANWKEAYINLKEQVNQ 37
                5678899************96 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00013
      REV1_C  16 egPneeDvealakyLkkvv..eeerdlekavavlkwlrvlleeeeeskeeeageaWekafre.vkeavqe 82 
                  +P  +D+ea  +  ++++  +e + +  a +vl w  + l+       +  ++aW +a++  ++e++++
  EEA22087.1  57 LKPSTRDLEAWITKWEELLleAERKSMVIADDVLDWSTRFLDAI-----RPLDDAWTTAYEItIEEKIED 121
                 57999*****99999999988888********************.....9**********9536666665 PP

>> Sulfotransfer_4  Sulfotransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.0     0.059   5.3e+02     123     171 ..      14      57 ..       2      61 .. 0.68
   2 ?   11.5   0.3   2.1e-05      0.19      97     175 ..      61     144 ..      59     150 .. 0.77

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.059
  Sulfotransfer_4 123 lalldpllellaklvellralvrrlfgagsdaedeeaakeayeehnerv 171
                      l  +   + ++a+++e++ +l +++ ++  ++ ++++ k+ y++h +++
       EEA22087.1  14 LDEA---DPVTANWKEAYINLKEQVNQG--RFISQRRIKDEYDQHLRSL 57 
                      3333...446677777777776666666..5788999999999998776 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 2.1e-05
  Sulfotransfer_4  97 eRdpekWlksmkktllalrsetls...rllalldpllellaklvellralvrrlfgag.s.daedeeaakeayeehnervrevv 175
                      +Rd e+W ++++++ll++ ++ +     +l + +++l++ ++l +++ ++++  ++++    + +++++++a+++  +++r+  
       EEA22087.1  61 TRDLEAWITKWEELLLEAERKSMViadDVLDWSTRFLDAIRPLDDAWTTAYEITIEEKiEdGTLTRRELANAFRRNLRKIRNRR 144
                      8**************999988554344788888889999999999999999999988754234566777777777777777655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (243 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       792  (0.0441742); expected 358.6 (0.02)
Passed bias filter:                      553  (0.0308439); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.29s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 1727.90
//
Query:       EEA22088.1  [L=1307]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.8e-38  132.0   0.2      5e-38  131.1   0.2    1.4  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    1.7e-07   31.0   0.0    4.3e-07   29.7   0.0    1.6  1  gag_pre-integrs  GAG-pre-integrase domain
    0.00049   20.3   0.0     0.0011   19.1   0.0    1.7  1  rve              Integrase core domain
  ------ inclusion threshold ------
      0.023   14.2   0.0      0.045   13.3   0.0    1.4  1  RVT_1            Reverse transcriptase (RNA-dependent DNA pol
      0.068   13.1   0.0       0.16   11.9   0.0    1.6  1  Flg_hook         Flagellar hook-length control protein FliK
        0.1   12.9   3.2       0.27   11.5   3.2    1.7  1  Orthopox_F14     Orthopoxvirus F14 protein


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  131.1   0.2   1.7e-41     5e-38       9     234 ..     812    1034 ..     803    1040 .. 0.91

  Alignments for each domain:
  == domain 1  score: 131.1 bits;  conditional E-value: 1.7e-41
       RVT_2    9 PkdrkaigsrWvftkkkddl.kevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeeelvvhqldvdsafLnaeldeevyvkqPpGfe 104 
                   k+++ +   W++  k+d++ + vk karlv++G  q    d  +++a  +   s r ++a+aa  +l + q d   af+na+ldee++++  pG+ 
  EEA22088.1  812 AKGKQILDCMWIYVYKQDKKgRLVKCKARLVVRG-DQEKRDDMRDTYAATLAARSFRTFMAIAARFDLELKQYDAVNAFVNAKLDEEIFMRMAPGYR 907 
                  577888999********999899***********.577889******************************************************96 PP

       RVT_2  105 idreeekvykLnkslyGlkqapllWnekidkvLkklgferseaesGlyvrgtgegklivalyvddlliagsdikil..edvkkelakkfklkdlgkv 199 
                     e++k+y+Lnk+lyGl+++pllW+++++++L klgf+  + e    +++     +++  yvdd+++a ++++ l  + + ++l +k++++   ++
  EEA22088.1  908 ---ESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFRAVPHEPCCMLKS----GVMLFFYVDDIVVAYKKSRQLeaNSILNQLRAKYNISGGEDL 997 
                  ...46****************************************999999....78999*********9999877225799*************** PP

       RVT_2  200 skfLGieiaq..eaggiklsladyiakvvkkfeltda 234 
                  + fLG+ i++  ++  i ls+a yi k++k ++ ++a
  EEA22088.1  998 EWFLGMRIIRdrSNKMIWLSQATYIDKIAKLADTQQA 1034
                  ********986568889***********998876655 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.7   0.0   1.4e-10   4.3e-07      19      66 ..     163     214 ..     146     215 .. 0.76

  Alignments for each domain:
  == domain 1  score: 29.7 bits;  conditional E-value: 1.4e-10
  gag_pre-integrs  19 knkssinlWHrRLGHpsfsrlkkLfkkgl...lpglkisk.sevCeaCqlgK 66 
                        k ++n+WH RLGHp+ + lk+L+       l g++++    +Ce+C  +K
       EEA22088.1 163 ERKADANRWHARLGHPGPEVLKHLAGAAKgvrLTGISKGPtTVECESCGTSK 214
                      35899********************8544334555554433559****9988 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   3.8e-07    0.0011       2     116 ..     228     344 ..     227     346 .. 0.86

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 3.8e-07
         rve   2 trpgelwqvDvtvvripdgggkayllvvvddfsrlilaealsdemdastvlalleravarfggve...pervlsDngseytskafrefla.dlgirvsf 96 
                 ++pge++ +D+  ++ ++  g++ l  ++d fs++++ ++++++   + +l++l+ +++++ +     p ++ +Dn  + +  +++ +l+ + +i +++
  EEA22088.1 228 HAPGEHLAIDFHDFAESTMHGEKTLMLITDRFSGFMWDYYMTSH-RGDEILETLKWFLDYLEKAYmisPVKIEMDNEIAKRP-EVKHYLEhEKRIILQP 324
                 89**********777799999***********************.**********99999999879**********976664.5555555157899999 PP

         rve  97 trpgrpqdnGkvErfhrtlk 116
                 ++++    nG +Er   ++k
  EEA22088.1 325 SPAHTQALNGGAERSGAIIK 344
                 99999999999999876666 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   1.5e-05     0.045     117     185 ..     901     983 ..     872     993 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.5e-05
                 .........TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T................TEEECTTEEEEEESSHHH..HHHHHH CS
       RVT_1 117 rv.nge.eskgryekkglpqGsvlSPllfnlfmnellrelrkra..........kgvtllrYaDDililskskee..lqelle 185
                 r+  g  es+++y+ +    G+  SPll++  +++ l +l  ra          +gv l  Y+DDi++++k+  +  ++++l+
  EEA22088.1 901 RMaPGYrESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFRAvphepccmlkSGVMLFFYVDDIVVAYKKSRQleANSILN 983
                 44344447899999999999***************9999999999***************************88844444454 PP

>> Flg_hook  Flagellar hook-length control protein FliK
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   5.4e-05      0.16      34      69 ..    1193    1228 ..    1185    1244 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 5.4e-05
                  ETTEEEEEEEE-SCHHHHHHHHTHHHHHHHHHCCTT CS
    Flg_hook   34 rggqlsvqltaenpetrelLeqnlprLreaLaaaGl 69  
                  r +  ++++  +n++t+ lLe+++prLr+ L+   +
  EEA22088.1 1193 RFQTPTLHVYCDNQQTLGLLEKDAPRLRTKLRHVDI 1228
                  55566899**********************987544 PP

>> Orthopox_F14  Orthopoxvirus F14 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   3.2   9.2e-05      0.27      32      70 ..     491     528 ..     480     531 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 9.2e-05
  Orthopox_F14  32 idedditellniltelGcdvdfdedfsdiaddvleslie 70 
                   +  ++it ll  l +lG d dfd++++d+ d + + +++
    EEA22088.1 491 VSTQEITRLLTKL-DLGTDADFDDEYADLIDHITDVVFD 528
                   5667888888776.79***************99887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1307 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       560  (0.0312343); expected 358.6 (0.02)
Passed bias filter:                      514  (0.0286686); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.83u 0.33s 00:00:01.15 Elapsed: 00:00:00.48
# Mc/sec: 8107.01
//
Query:       EEA22089.1  [L=606]
Description: oxidoreductin [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.6e-135  451.9   0.0     2e-135  451.6   0.0    1.1  1  ERO1      Endoplasmic Reticulum Oxidoreductin 1 (ERO1)


Domain annotation for each model (and alignments):
>> ERO1  Endoplasmic Reticulum Oxidoreductin 1 (ERO1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  451.6   0.0  1.1e-139    2e-135       1     354 []      68     464 ..      68     464 .. 0.96

  Alignments for each domain:
  == domain 1  score: 451.6 bits;  conditional E-value: 1.1e-139
        ERO1   1 klrplLkeLvk.tdfFryfkvnld.keCpfweddeglCanraCavee.ceeeeiPekwraeelsklertls.......................eeees 73 
                 +++plLk++++ +dfF+y+++nl+ k Cpfwed+ +lC+n aCav++ ++ee++P  wr eelskle + +                       +  es
  EEA22089.1  68 EIHPLLKSVTRdNDFFSYYRLNLYnKACPFWEDEYSLCGNIACAVNTiDSEEDLPPVWRIEELSKLEGPRAhhpgkqqqkerpserplqgglgdSVGES 166
                 599*******999***********99*********************778899****************999*********************9999** PP

        ERO1  74 avkeakeeeeaeeedyceledeeeee.avyvdLlenperfTgYkGesaervWkaiYeencfkeeseseese........................ekel 147
                 +v e+++e+  +e+dyc++ede + + ++yv+L++nperfTgY+G+ +++vW+aiY+encf +  +s++s+                        + + 
  EEA22089.1 167 CVLEYDDEC--DERDYCVPEDEGALAkGDYVSLVDNPERFTGYAGQGSHQVWDAIYRENCFVKPPSSPSSQlaplhgmqiqaandfrnvlqreqpQPQP 263
                 *****9999..668*******999777**********************************887777666689********************999999 PP

        ERO1 148 eelclekrvfyrliSGlhasisihlaaeylnqetgewepnlelfkervgkhperlenlYfnyalvlrAvaklapyleelefstgeeeedeetkellkee 246
                 +++clekrvf+r+iSG+hasis+hl++eylnq+t+ew+pn++++k+r+++hper++nlYfnyalv+rAvakl++yl++++f++ ++e+d  t++++   
  EEA22089.1 264 DDECLEKRVFHRVISGMHASISTHLCWEYLNQTTNEWGPNVQCYKDRLHNHPERISNLYFNYALVSRAVAKLNNYLKKYKFCSFDPEQDLATRKQV--- 359
                 ********************************************************************************************9993... PP

        ERO1 247 lakellsalsskekafdesklfkdkeeaeelkeefrerfrnisrimdCVgCekCrLwGKlqttGlgtAlkilfeeeekeeekklkLernevvALintle 345
                    +l+++l+s++ +fde+ +f+ +e+a +lke+fr+rfrn+sr+mdC+gC+kCrLwGKlq++G+gtAlk+lf+ +e++e+++  L+r+e+vAL+nt++
  EEA22089.1 360 --LSLTEKLNSQPPIFDEAVMFQ-DEHAMDLKEDFRNRFRNVSRLMDCIGCDKCRLWGKLQVNGYGTALKVLFDYDETKESDNPPLRRTELVALMNTFA 455
                 ..46667778899**********.89*****************************************************999***************** PP

        ERO1 346 rlseSieav 354
                 r+s+Si+av
  EEA22089.1 456 RISNSIAAV 464
                 ******986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (606 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       532  (0.0296726); expected 358.6 (0.02)
Passed bias filter:                      449  (0.0250432); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.24s 00:00:00.84 Elapsed: 00:00:00.42
# Mc/sec: 4348.04
//
Query:       EEA22090.1  [L=440]
Description: peroxisomal membrane protein (Pex13), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.9e-53  179.6   0.1    5.5e-53  179.2   0.1    1.2  1  Peroxin-13_N  Peroxin 13, N-terminal region
    2.6e-09   36.6   0.0    4.5e-09   35.9   0.0    1.4  1  SH3_2         Variant SH3 domain
    2.9e-08   33.2   0.0    5.2e-08   32.4   0.0    1.4  1  SH3_1         SH3 domain
  ------ inclusion threshold ------
       0.09   13.2   0.0       0.15   12.5   0.0    1.3  1  hSH3          Helically-extended SH3 domain


Domain annotation for each model (and alignments):
>> Peroxin-13_N  Peroxin 13, N-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  179.2   0.1   1.2e-56   5.5e-53       2     145 .]     141     281 ..     140     281 .. 0.90

  Alignments for each domain:
  == domain 1  score: 179.2 bits;  conditional E-value: 1.2e-56
  Peroxin-13_N   2 ltqsaeestratfqliesivgafgsfaqmLestymAthsSFfavvsvaeqfgrLketlgsvlsifalirllkkilskllglllekkkkekskaeefw 98 
                   lt+s+++st+atfq+iesivgafg+faqmLestymAthsSFfa+vsvaeqfg+L++tlgsvl+if+lir+++++++kl+g+    +++++ + ++f 
    EEA22090.1 141 LTNSFSQSTAATFQMIESIVGAFGGFAQMLESTYMATHSSFFAMVSVAEQFGNLRNTLGSVLGIFTLIRWFRTLMAKLTGRP-LPADATALTPSAF- 235
                   899******************************************************************************5.7999999999999. PP

  Peroxin-13_N  99 kkfessskkkeekeskeekkkk..kisskplllflaaviglPyllkkli 145
                   + f + +++ +   + +++ ++  ++s+kp+++f++av+glPyl+ kli
    EEA22090.1 236 SAFLNGRSAPA---TLPDGGPApaRPSRKPFFMFILAVFGLPYLMGKLI 281
                   99999884443...33334443336**********************98 PP

>> SH3_2  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.9   0.0     1e-12   4.5e-09       1      55 [.     317     378 ..     317     380 .. 0.85

  Alignments for each domain:
  == domain 1  score: 35.9 bits;  conditional E-value: 1e-12
                 EEEESS-B-SCGCCB....--B-TTEEEEEE..EEEECT.....TEEEEEE.CCCEEEEEGCGEE CS
       SH3_2   1 yvraiedyvgedkse....LsfkkGdvikvlslgskdsd.....gwwegev.gGrvGlfPsslve 55 
                 ++r++ dy++   +     L  kkGd+++v+   sk+++     +ww+++  +G vG+ Ps ++e
  EEA22090.1 317 FCRVLYDYTPDAQNTagidLAVKKGDIVAVI---SKSDPmgnpsEWWRCRArDGGVGYLPSPYLE 378
                 689999****4444456**************...7766678899*****887*********9987 PP

>> SH3_1  SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.4   0.0   1.2e-11   5.2e-08       1      48 []     319     374 ..     319     374 .. 0.89

  Alignments for each domain:
  == domain 1  score: 32.4 bits;  conditional E-value: 1.2e-11
                 EESSSBEXSS....TTBXEBSTTEEEEEEEECSS.....SEEEEEETTSTEEEEEEG CS
       SH3_1   1 iAlYDYeaee....sdELsfkkGDviivleksed.....gWwkgrlkgtgkeGliPs 48 
                 ++lYDY++        +L  kkGD++ v++ks+      +Ww++r +++  +G+ Ps
  EEA22090.1 319 RVLYDYTPDAqntaGIDLAVKKGDIVAVISKSDPmgnpsEWWRCRARDG-GVGYLPS 374
                 689***9877445567*****************999999*********6.6*****8 PP

>> hSH3  Helically-extended SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   3.3e-05      0.15      25      70 ..     328     378 ..     317     383 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 3.3e-05
        hSH3  25 skklggkdLpvkrgeildviqktd.....dkkvlcrneeGkygyvlrsall 70 
                 ++ ++g dL+vk+g+i+ vi+k+d     ++   cr ++G  gy+++ +l 
  EEA22090.1 328 AQNTAGIDLAVKKGDIVAVISKSDpmgnpSEWWRCRARDGGVGYLPSPYLE 378
                 5677899**************9974443356789**********9988775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (440 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       532  (0.0296726); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3052.02
//
Query:       EEA22091.1  [L=566]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    3.8e-27   95.2  38.1    3.8e-27   95.2  38.1    1.9  2  MFS_1       Major Facilitator Superfamily
     0.0005   19.5  21.3     0.0028   17.0  21.3    1.9  1  MFS_4       Uncharacterised MFS-type transporter YbfB
  ------ inclusion threshold ------
        1.5    8.8   6.5       0.84    9.6   1.3    2.8  3  Flavi_NS4A  Flavivirus non-structural protein NS4A


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.2  38.1   6.3e-31   3.8e-27       3     349 ..      93     430 ..      88     434 .. 0.75
   2 !   15.1   9.9   1.3e-06     0.008      46     181 ..     338     471 ..     337     499 .. 0.86

  Alignments for each domain:
  == domain 1  score: 95.2 bits;  conditional E-value: 6.3e-31
       MFS_1   3 laaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlgag 100
                 +aa ++ ++ +   p+l   la+d+++s   ++++ t+   g+a++ l++ +l+d + rr +ll+  +l+a ++l l++ + ++ +++v  +++++++ 
  EEA22091.1  93 FAATFTVANLYYSHPILD-VLAKDFNVSQERASIIPTCAQGGYAAGLLFICPLGDLIKRRGMLLWLTFLTATMTLGLCL-TKSFdAFVVISFIMSITT- 188
                 333444444444555666.99************************************6666888888888888344446.88899************6. PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeeekgtgpaplvpa 199
                 +   +++ l+  ++p+++r+ a++++ +g  lG +l+ ll+g++a + +Wr v+++  ++    +vl ++++p+ p ++k+ s          + l+++
  EEA22091.1 189 VTPQVMLPLVGTLAPPNKRATALSIVVSGLMLGLLLARLLSGIIANYSSWRNVYWMSLALQYAILVLLWMWMPDYPQSNKNISYF--------RILFSI 279
                 *********************************************************9999999888666666666666666543........345555 PP

       MFS_1 200 wkallkdpvlw.illialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavt 297
                 +++l+k+pvl  + +ia+l  ++++s+ +tl++l+  + +++s  +++g+    +al+g++ +l++  +++r+  r+++ +++l+++++al  ++++++
  EEA22091.1 280 LELLVKHPVLVqASIIAFLNSSCFTSFWTTLTFLLSGDPYHYS-TVIIGF----FALAGIGPMLFGPLFANRFIDRFPIHVSVLVGICLALVGIVVGTY 373
                 8899999999877888888888777777777777779999999.566663....333333334444444466555566666666666666666666666 PP

       MFS_1 298 ...ssavllllvlvliGfglgfvfpsllalasdlapp..eeagtasglfntagslgg 349
                    ++ +  ++  +l+ fg+ +++++  +++  +ap+  ++  ta+ +f+++g+l g
  EEA22091.1 374 tgkHTVAGPIIQAILFDFGAQITQIANRTAIYGVAPKaaSRVNTAFMVFSFCGQLTG 430
                 333335555557777999888887777777777776544777799999999998766 PP

  == domain 2  score: 15.1 bits;  conditional E-value: 1.3e-06
       MFS_1  46 avaslplGrlsdrfGrrrvlllglllfalglllllfa..sslwlllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllgg 142
                 +++ l++ r++drf     +l+g+ l ++g+++++++  +++   ++  +l  +ga +   a  ++i  ++pk   +r++  +++++ +G + g ++g 
  EEA22091.1 338 LFGPLFANRFIDRFPIHVSVLVGICLALVGIVVGTYTgkHTVAGPIIQAILFDFGAQITQIANRTAIYGVAPK-AASRVNTAFMVFSFCGQLTGTAVGN 435
                 6788999*******6666999999999999888888677777788999999**********************.************************* PP

       MFS_1 143 llasslgWravfyilaivsllafvlfllllpeepperkr 181
                  l++++gW  +  +  +++  a +   +ll++ p+e ++
  EEA22091.1 436 KLYAQGGWIRSGSASVGFMGGATI---VLLLRGPKETRW 471
                 *******98888888888888877...566666665554 PP

>> MFS_4  Uncharacterised MFS-type transporter YbfB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0  21.3   4.6e-07    0.0028      14     346 ..     107     446 ..     100     463 .. 0.72

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 4.6e-07
       MFS_4  14 piLPallaegqlslsqagllaaaNylGYLvGallaafalsagaeRlr.llagllatvllllamaltesfaaflliRflaGvasAvvlvfgsslvlahaa 111
                 piL +l ++ ++s   a+++ +    GY +G l+    l    +R + ll  +++t+ ++l   lt+sf af++i f+  ++  +  v+    v   a 
  EEA22091.1 107 PILDVLAKDFNVSQERASIIPTCAQGGYAAGLLFI-CPLGDLIKRRGmLLWLTFLTATMTLGLCLTKSFDAFVVISFIMSITTVTPQVMLPL-VGTLAP 203
                 99*****************************8855.777777777775889999************************99999888887764.444556 PP

       MFS_4 112 aarrervgallfaGvGlGiavsgllvllllqlglsasslWlalavlsavllllvalllp..raalreasaaae...aakaeqkslpllalllaYglaGf 205
                 + +r++ ++++ +G  lG +++ ll  ++ ++    ++ W+ la l  ++l+l+++++p   +++++ s  +      + + k+  l++  +  +l+  
  EEA22091.1 204 PNKRATALSIVVSGLMLGLLLARLLSGIIANYSSWRNVYWMSLA-LQYAILVLLWMWMPdyPQSNKNISYFRIlfsILELLVKHPVLVQASIIAFLNSS 301
                 78999999***************999999888888887888876.566777889999994322222222222211122344555566777777888887 PP

       MFS_4 206 GYiitatFlvaiardg.aggalleallWllvGla.aivgvlvwlrvakrsglrralaaa..llieavgvllsllspsplglivssvllGltflaitalv 300
                  +    t l  +      + + +   +  l+G++ ++ g+l  +r  +r  ++  + +   l++ ++ v   +  ++++g+i+ ++l+      it+++
  EEA22091.1 302 CFTSFWTTLTFLLSGDpYHYSTVIIGFFALAGIGpMLFGPLFANRFIDRFPIHVSVLVGicLALVGIVVGTYTGKHTVAGPIIQAILFDFGA-QITQIA 399
                 776655555544444437778888889999999934569988888888876665555440055555555555667999********974333.344444 PP

       MFS_4 301 l.qlarelappat.rrllglmTasfgigQilGpllasllaeatgslal 346
                   +++  +ap+a  r + ++m  sf  gQ+ G ++ + l+++ g + +
  EEA22091.1 400 NrTAIYGVAPKAAsRVNTAFMVFSFC-GQLTGTAVGNKLYAQGGWIRS 446
                 30455667787776788999999995.******999999998775544 PP

>> Flavi_NS4A  Flavivirus non-structural protein NS4A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   1.3   0.00014      0.84      48     115 ..     215     284 ..     206     296 .. 0.83
   2 ?    0.4   0.0     0.096   5.7e+02      89     111 ..     309     331 ..     299     335 .. 0.87
   3 ?   -2.5   0.0      0.72   4.3e+03      49      66 ..     417     434 ..     396     469 .. 0.55

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00014
  Flavi_NS4A  48 ieilmllilialltsGvvlfflsgkGlsktsialltviassallflasv..kpthiaavillefvlmvll 115
                 +  lml +l+a l sG++  + s + +  +s+al   i     +++       + i++  +l+ +l +l+
  EEA22091.1 215 VSGLMLGLLLARLLSGIIANYSSWRNVYWMSLALQYAILVLLWMWMPDYpqSNKNISYFRILFSILELLV 284
                 56689999******************************99999999875225678999999888876655 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.096
  Flavi_NS4A  89 allflasvkpthiaavillefvl 111
                 +l fl s +p h ++vi+ +f l
  EEA22091.1 309 TLTFLLSGDPYHYSTVIIGFFAL 331
                 689999***********999987 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 0.72
  Flavi_NS4A  49 eilmllilialltsGvvl 66 
                 +  m++ + + lt+  v 
  EEA22091.1 417 TAFMVFSFCGQLTGTAVG 434
                 445666666666665554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (566 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1255  (0.0699983); expected 358.6 (0.02)
Passed bias filter:                      514  (0.0286686); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.71u 0.35s 00:00:01.06 Elapsed: 00:00:00.50
# Mc/sec: 3421.53
//
Query:       EEA22092.1  [L=591]
Description: hypothetical protein PMAA_058720 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (591 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       448  (0.0249875); expected 358.6 (0.02)
Passed bias filter:                      429  (0.0239277); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 4018.01
//
Query:       EEA22093.1  [L=542]
Description: autophagy protein Apg6, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.6e-74  247.7   0.0    9.3e-74  247.2   0.0    1.2  1  APG6           Apg6 BARA domain
    9.2e-41  139.5  13.4    1.6e-40  138.7  13.4    1.4  1  APG6_N         Apg6 coiled-coil region
  ------ inclusion threshold ------
       0.05   13.4   8.7       0.08   12.8   8.7    1.2  1  KASH_CCD       Coiled-coil region of CCDC155 or KASH
       0.66   10.2   8.2        1.8    8.8   7.1    2.3  2  Lge1           Transcriptional regulatory protein LGE1
       0.73   10.3   4.6        2.2    8.7   4.6    1.9  1  CENP-H         Centromere protein H (CENP-H)
        4.2    7.6  14.2         49    4.1  12.9    2.7  2  Jnk-SapK_ap_N  JNK_SAPK-associated protein-1
        5.6    7.1  17.5       0.19   11.9  10.7    2.0  2  ATG16          Autophagy protein 16 (ATG16)
          7    6.8   7.6         16    5.7   7.6    1.6  1  bZIP_2         Basic region leucine zipper


Domain annotation for each model (and alignments):
>> APG6  Apg6 BARA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  247.2   0.0   4.1e-77   9.3e-74       1     179 []     298     511 ..     298     511 .. 0.97

  Alignments for each domain:
  == domain 1  score: 247.2 bits;  conditional E-value: 4.1e-77
        APG6   1 LrktnvyndaFkIshdgkfgtInglrLGrlpsekvewsEinAAlGqtvlLLatiaeklnlkfqeyklvplGstSkiekleeksee.............. 85 
                 L++tnvyndaF+I hdg fgtInglrLGrl++ +v+w EinAA+Gqt+lLLatiaekl+++f++y+l+p+Gs Skiek+e+++++              
  EEA22093.1 298 LQRTNVYNDAFCIGHDGFFGTINGLRLGRLANPSVDWAEINAAWGQTCLLLATIAEKLDFQFRGYRLKPMGSNSKIEKFEDSAQNssqsssqavpgads 396
                 89****************************************************************************9999888899*********** PP

        APG6  86 ........vlelyssgelklgllfserkfDkamvafleclkqlaekvekedk..............elelPYkikkdkdkigdlsiklqfne.eeeWtk 161
                         vl+l+ssg+++l+l + +r+fD++mvaflecl+ql+ +ve++ +               l+lPY+ik+d  kigd+sikl fn+ +e+Wt+
  EEA22093.1 397 sssaqkstVLDLFSSGDMPLNLPWIHRRFDAGMVAFLECLRQLGVYVENTPVpaasrrgqqginttGLKLPYEIKRD--KIGDASIKLGFNQnDETWTR 493
                 ***********************************************997778889999999999999******888..******************** PP

        APG6 162 AlkllLtnlkwllawvss 179
                 A+k++Lt++k+lla++s+
  EEA22093.1 494 ACKYTLTCCKFLLAHASN 511
                 ***************986 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.7  13.4   7.1e-44   1.6e-40       1     133 []     167     295 ..     167     295 .. 0.99

  Alignments for each domain:
  == domain 1  score: 138.7 bits;  conditional E-value: 7.1e-44
      APG6_N   1 PlCeeCtdlLleeldkqleqaekerdaYeeflkklkkekkeeekqdeeleeleeeleklekeeeelleeLkelekereeleaelaaleeelealeeeee 99 
                 P+C+eCtdlL+e+l k+l++++kerdaY +flk+++++ ++e     e+e++e++l+ + +eee++ +eL +leke+++l++e+a+leee+++l+ +ee
  EEA22093.1 167 PICTECTDLLVEGLHKRLASTTKERDAYISFLKNINASIPTEA----EVEAAEKSLKSTLQEEEAAYQELLALEKEKADLDREIADLEEESRQLDLDEE 261
                 9*************************************99987....**************************************************** PP

      APG6_N 100 rfwreynelqlelleleeeldsleaqyehaqnql 133
                 +fwre+n ++l l+++++e+d+l+++y+h+++ql
  EEA22093.1 262 EFWRERNTFALSLTDFQDERDALNMRYDHDSRQL 295
                 ********************************98 PP

>> KASH_CCD  Coiled-coil region of CCDC155 or KASH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   8.7   3.6e-05      0.08      37     130 ..     207     300 ..     182     304 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 3.6e-05
    KASH_CCD  37 tnakLteeieeLkkklkstQqalqkaklleeEleelkalvkeleEkrarlkaqnkqlekenqsLiakiesLqeenikllaekdelkkklkeLlk 130
                 t a   +  + Lk  l+    a q+  +le+E ++l + + +leE+ ++l   +++  +e++     +++ q+e   l +  d+  ++l+ L +
  EEA22093.1 207 TEAEVEAAEKSLKSTLQEEEAAYQELLALEKEKADLDREIADLEEESRQLDLDEEEFWRERNTFALSLTDFQDERDALNMRYDHDSRQLERLQR 300
                 555566666789999999999999999************************************************9999999999999998865 PP

>> Lge1  Transcriptional regulatory protein LGE1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   7.1   0.00081       1.8      12      58 ..     212     258 ..     180     262 .. 0.82
   2 ?   -1.0   0.0      0.95   2.1e+03      40      59 ..     266     285 ..     257     287 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00081
        Lge1  12 estlkkiesklkeiesldkqleelklkvlkleleldlleeqierdaL 58 
                 e+  k+++s+l+e e+++++l  l++++  l  e + lee +++  L
  EEA22093.1 212 EAAEKSLKSTLQEEEAAYQELLALEKEKADLDREIADLEEESRQLDL 258
                 45559*************************************99766 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.95
        Lge1  40 lkleleldlleeqierdaLr 59 
                 + + ++l+l+  q erdaL+
  EEA22093.1 266 ERNTFALSLTDFQDERDALN 285
                 56788899999999*****9 PP

>> CENP-H  Centromere protein H (CENP-H)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   4.6   0.00098       2.2       1      72 [.     218     299 ..     180     303 .. 0.80

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00098
      CENP-H   1 llplieqrdelssellklsqelrelqeeltevekenlrlkrknrelaael.l.elakekesek........eklkeelekle 72 
                 l+ ++++ +++ +ell+l++e ++l +e++++e+e+++l   ++e ++e  +  l+  + +++        ++++++le+l+
  EEA22093.1 218 LKSTLQEEEAAYQELLALEKEKADLDREIADLEEESRQLDLDEEEFWRERnTfALSLTDFQDErdalnmryDHDSRQLERLQ 299
                 5678888899999999999999999999999999999999999999988754566555555555567666555666666665 PP

>> Jnk-SapK_ap_N  JNK_SAPK-associated protein-1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1  12.9     0.022        49      50     126 ..     220     302 ..     183     306 .. 0.77
   2 ?    1.3   0.0      0.16   3.5e+02      81     135 ..     335     389 ..     331     404 .. 0.87

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.022
  Jnk-SapK_ap_N  50 aeleelreeleqL......eteyerekelrkraeeeleeiedqweeerkelqekveqleeenrelelkaknaadqlsrleeke 126
                    ++l+e +++ ++L      + +++re ++ +++ ++l + e+++ +er+++   +++ ++e++ l+++ +  + ql+rl++++
     EEA22093.1 220 STLQEEEAAYQELlalekeKADLDREIADLEEESRQLDLDEEEFWRERNTFALSLTDFQDERDALNMRYDHDSRQLERLQRTN 302
                    333333333333300000033345566666666699*******************************************9875 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.16
  Jnk-SapK_ap_N  81 eeiedqweeerkelqekveqleeenrelelkaknaadqlsrleekeaelkkeysk 135
                     ei  +w + +  l +  e+l+ + r + lk   ++ ++++ e++ +++++++s+
     EEA22093.1 335 AEINAAWGQTCLLLATIAEKLDFQFRGYRLKPMGSNSKIEKFEDSAQNSSQSSSQ 389
                    5778889999999999999999999999999999999999999999999887776 PP

>> ATG16  Autophagy protein 16 (ATG16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9  10.7   8.6e-05      0.19     102     181 ..     209     302 ..     182     303 .. 0.78
   2 ?   -2.9   0.5         3   6.8e+03      40      71 ..     379     391 ..     363     407 .. 0.38

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 8.6e-05
       ATG16 102 qrllelneelqkleeklkedeerlaeleaeraaletklkdreeelrekeklvq..............dlqDElsaLqlqlnqaEeklrklekEN 181
                   + +++++l+   ++ ++  ++l +le+e+a+l ++++d+eee r+++   +              d+qDE +aL++++ +   +l++l++ N
  EEA22093.1 209 AEVEAAEKSLKSTLQEEEAAYQELLALEKEKADLDREIADLEEESRQLDLDEEefwrerntfalsltDFQDERDALNMRYDHDSRQLERLQRTN 302
                 4566677777777777777777777788888888888888888888877666677778888888888889999999999888888888888765 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 3
       ATG16  40 klekaaasakssksskksakekeasasqsnsk 71 
                 +++++++s+++                   ++
  EEA22093.1 379 SAQNSSQSSSQ-------------------AV 391
                 22222222111...................11 PP

>> bZIP_2  Basic region leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   7.6    0.0072        16      14      54 .]     212     252 ..     212     252 .. 0.97

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0072
                 XXXXX-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_2  14 eAarrsRekkkakeeeleervkeLeeeNaqLrqkveqLeke 54 
                 eAa +s +   ++ee   +++  Le+e+a L ++++ Le e
  EEA22093.1 212 EAAEKSLKSTLQEEEAAYQELLALEKEKADLDREIADLEEE 252
                 8*************************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (542 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       965  (0.0538234); expected 358.6 (0.02)
Passed bias filter:                      543  (0.0302861); expected 358.6 (0.02)
Passed Vit filter:                        91  (0.00507558); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.65u 0.25s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 3590.85
//
Query:       EEA22094.1  [L=543]
Description: Myb-like DNA-binding domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-19   69.8   0.4    2.9e-19   68.6   0.4    1.8  1  Scm3      Centromere protein Scm3


Domain annotation for each model (and alignments):
>> Scm3  Centromere protein Scm3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.6   0.4   1.6e-23   2.9e-19       4      53 ..      23      71 ..      20      72 .. 0.95

  Alignments for each domain:
  == domain 1  score: 68.6 bits;  conditional E-value: 1.6e-23
                HHHHHHHHHHHHHHHHHHHHHSG..GGSS--B-TTT-SB-XXXXXXXXXX CS
        Scm3  4 lreesderlkkrwesifeKYeridfedqgDEIDlatgeivvDnGhlrelr 53
                +r+++d++lk+ +e ifeKY++ df+d+gDEIDl tgeiv++ Gh ++++
  EEA22094.1 23 ARARNDQKLKSLFEGIFEKYGK-DFSDIGDEIDLSTGEIVINKGHVQRME 71
                799*******************.*************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (543 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       715  (0.0398795); expected 358.6 (0.02)
Passed bias filter:                      367  (0.0204696); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.50
# Mc/sec: 3298.93
//
Query:       EEA22095.1  [L=443]
Description: cysteine synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.8e-62  209.2   0.1    1.3e-61  208.7   0.1    1.2  1  PALP      Pyridoxal-phosphate dependent enzyme


Domain annotation for each model (and alignments):
>> PALP  Pyridoxal-phosphate dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  208.7   0.1     7e-66   1.3e-61       2     294 .]      72     413 ..      71     413 .. 0.91

  Alignments for each domain:
  == domain 1  score: 208.7 bits;  conditional E-value: 7e-66
                 GGCSSS--EEEECCTCCCCCCEEEEEEGGGS.TTSBTTHHHHHHHHHHHHTT.....TTTSEEEEEBSSHHHHHHHHHHHHHT-EEEEEEETTS-HHHH CS
        PALP   2 tlgigpTPlvrlprlskelgvplflKlEsln.ptgSfKdRgaeyllarlkeg.....tgaktvveassGNhgralAaaaallGlkvtivvpadaspekv 94 
                 ++ ig+TPl r+++ls+e+g+++++K E+ln  +gS KdR a +++++++++      +++++ e++sG +g++lA  a++ G+ ++i++p+d   ek 
  EEA22095.1  72 EGCIGNTPLFRIKSLSEETGCEILAKAEFLNgAGGSPKDRVALSMIETAEREgslrpHSGDVIYEGTSGSTGISLATLARARGYLAHICMPSDQAMEKS 170
                 6789***************************66***************6666688888***************************************** PP

                 HHHHHTT-EEEEECCH........HHHHHHHHHHHHHH................................STTCEE--TTTSHHHHHH.HHTHHHHHHH CS
        PALP  95 allrllGaevvevggd........ydeavaaaaelaae................................gegaylvsqfdnptvieg.ygtiglEile 152
                 +ll  lGa v +v+          +++a+++a+    +                                ++  ++++qf+n ++  +  + +g+Ei++
  EEA22095.1 171 DLLLKLGAVVDRVPPApiveqanfVNRARNLAR----DrtassntspdklssksgtqltttdpttepgvsTGRGFFTDQFENAANHVAhFKGTGPEIYA 265
                 *************44444332233555555555....4555589999999999****************99999**********99999********** PP

                 HTTTTEEEEEEE-SSSHHHHHHHHHHHHHSTT-EEEEEEECTTCGGTTCCS..S.SS..B..........SSS.CCSTCSCGTTCCHHHHSEEEEEEEE CS
        PALP 153 qlggkpdavvvpvGgGgliaGiaaglkerrpdvrvigvepegsdalarslragrrvtvpvs.........dtiadglavgspselafelldrlvdeivt 242
                 q+ggk+da+v+++G+Gg+i+G+a +lk r pd+++i ++p+gs  ++r +  g   ++++          dti++g++++   + +fe+ ++l+d+++ 
  EEA22095.1 266 QCGGKLDAFVAGAGTGGTISGVALFLKPRLPDIKIILADPQGSGLYNRVR-YGVMFDIKERegtrrrpqvDTIVEGIGIN-RQTANFEAGRELIDDAIR 362
                 *****************************************999999999.5555555555666666666**********.9***************** PP

                 EEHHHHHHHHHHHHHHHSB-B-HHHHHHHHHHHHHHHHCCTTCEEEEEEE-B CS
        PALP 243 vsdeealeamrllarregivvepssaaalaalklreagelkegdrvvviltg 294
                 v+d++a++++r+l +++gi+++ ssa++  a+  + a el++g r+v+ilt+
  EEA22095.1 363 VTDAQAMAMARWLVEKDGIFMGSSSAVNCFAA-VKTALELGPGHRIVTILTD 413
                 ********************************.*****************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (443 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       303  (0.0169); expected 358.6 (0.02)
Passed bias filter:                      257  (0.0143343); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.24s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 3047.42
//
Query:       EEA22096.1  [L=504]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.8e-42  144.4   0.0    6.9e-42  143.9   0.0    1.2  1  Methyltransf_28  Putative S-adenosyl-L-methionine-dependent m
  ------ inclusion threshold ------
       0.15   11.9   0.0       0.33   10.8   0.0    1.6  1  PRMT5            PRMT5 arginine-N-methyltransferase


Domain annotation for each model (and alignments):
>> Methyltransf_28  Putative S-adenosyl-L-methionine-dependent methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  143.9   0.0   7.7e-46   6.9e-42       2     255 ..     187     461 ..     186     467 .. 0.84

  Alignments for each domain:
  == domain 1  score: 143.9 bits;  conditional E-value: 7.7e-46
  Methyltransf_28   2 laiwlleewqalgrpskklrliElGpGkGtLmadvLrtlrkflpefyealeyhlvEaSpqlrerQknrLkekakevkk....estvkslgvkve 91 
                      +a++l+++++ +  p ++l ++E+G+G+GtLm ++L+ +r+  pe+y++++++++E+S++l+++Qk++L+ + ++ ++    ++ +ks+ +   
       EEA22096.1 187 IARYLVTNYRLSLYPYHDLIIYEMGAGNGTLMLNILDFIRDSDPEVYARTKFKIIEISSSLAKVQKENLQASLSAGGHtghvQIINKSIFD--- 277
                      9**********************************************************************99988887767777777777... PP

  Methyltransf_28  92 WleelkeipeetgfilanEffDaLPihqfertedg..wrellveltpe...............kkakek....efrltlspsetdplsevlpkl 164
                      W e ++     ++f+la E+fD++ +++++++ ++   ++  v ++                 +         + + + +p +t+ +s++ +++
       EEA22096.1 278 WNEYIH----SPCFFLALEVFDNFSHDAIRYDYETemPQQGGVVIDSDgefceyynttldplaS----RflraRQAASRRPFPTPLPSKLARSI 363
                      999875....89******************8877764477777777556777777555544441....13432334445788887788888888 PP

  Methyltransf_28 165 skrlkaleegsr..ieispeaeallediaerlakegGaaLiiDYge.ssse..pngtL.rairkhklv..d.pleepGevDltadvDFtalaea 249
                      ++ l   + +++   +i++++++++ ++  +++   +++ + D+   ++ +   n+++ +  +k+++v  + p++++G++D+++++DF+ ++ +
       EEA22096.1 364 RSSLPIGKRDYTlpEYIPTRLMQFFDILRDYFPA--HRLVTSDFSSlPDAVpgLNAPVvQTRYKRRTVpvStPFVHQGYFDIFFPTDFNVVEDL 455
                      888877555555226*******************..**********99998999999988888888888955********************** PP

  Methyltransf_28 250 aeeasg 255
                      +++++g
       EEA22096.1 456 YRAITG 461
                      *99987 PP

>> PRMT5  PRMT5 arginine-N-methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   3.7e-05      0.33      42     134 ..     182     280 ..     179     307 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 3.7e-05
                 HHHHHHHHHHHHHCTCCGTCC.-EEEEEEES-TTSHHHHHHHHHHHHHCCC.....EEEEEEEES-HHHHH..HHHHHHHHHTTCCGCEEEES-CCCCC CS
       PRMT5  42 lYeeAiekalsdlkkekkkksekklvilvvGaGRGplvdralkaleetkvt.....kvkivavEKnpnavv..tLqkkvneekWeekveviksdmrelk 133
                  Y eAi+++l+++ + +     ++l+i+ +GaG G l+ ++l+ ++ ++ +     k+ki+ +    + v    Lq+ ++    + +v++i++ + +++
  EEA22096.1 182 YYGEAIARYLVTNYRLSLYPY-HDLIIYEMGAGNGTLMLNILDFIRDSDPEvyartKFKIIEISSSLAKVQkeNLQASLSAGGHTGHVQIINKSIFDWN 279
                 599*******99998887776.99*******************99988743344335555544443333321246666666667788999999888887 PP

                 H CS
       PRMT5 134 a 134
                 +
  EEA22096.1 280 E 280
                 6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (504 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       506  (0.0282224); expected 358.6 (0.02)
Passed bias filter:                      459  (0.025601); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.33s 00:00:00.92 Elapsed: 00:00:00.48
# Mc/sec: 3139.91
//
Query:       EEA22097.1  [L=197]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (197 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       805  (0.0448993); expected 358.6 (0.02)
Passed bias filter:                      294  (0.016398); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.45
# Mc/sec: 1321.64
//
Query:       EEA22098.1  [L=197]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (197 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       805  (0.0448993); expected 358.6 (0.02)
Passed bias filter:                      294  (0.016398); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1327.73
//
Query:       EEA22099.1  [L=249]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-16   58.9   0.0    6.8e-16   58.3   0.0    1.3  1  PX        PX domain


Domain annotation for each model (and alignments):
>> PX  PX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.3   0.0   3.8e-20   6.8e-16      17     110 ..     151     244 ..     137     247 .. 0.82

  Alignments for each domain:
  == domain 1  score: 58.3 bits;  conditional E-value: 3.8e-20
                 SSEEEEEEEEEETTS.SSEEEEEEEHHHHHHHHHHHHHHHT..TSTSTSSSTSGSSSSSCTTSHHHHHHHHHHHHHHHHHHHTSCHHHHSHHHHHHH CS
          PX  17 kkhsyylyevelktg.akewtvkRrYsdFeeLhskLlrkfp..rvkiPplPkkvlfgsvrkkdeefiekrrkgLeeyLqrllnhpelrnsevlteFL 110
                 +++ y+++ + ++t       +  rYs+F eL+s L   fp  +  +PplP+k+++ +   + ++f+e+rr gL+ +L+++l +pe++ s+vl++FL
  EEA22099.1 151 GIGAYVVWMCNVQTLdGGPMMIPMRYSEFDELRSLLATAFPhaCNALPPLPPKSVLFK---FRPKFLESRRIGLQYFLNCVLLNPEFSGSPVLKDFL 244
                 344444444444444347888889*****************99999********9986...***********************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (249 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       471  (0.0262703); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.30s 00:00:00.80 Elapsed: 00:00:00.49
# Mc/sec: 1536.80
//
Query:       EEA22100.1  [L=583]
Description: IQ calmodulin-binding motif protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.4e-05   23.2   1.5     0.0001   21.8   1.5    1.9  1  IQ              IQ calmodulin-binding motif
  ------ inclusion threshold ------
       0.12   12.6   0.6       0.56   10.4   0.6    2.2  1  UPF0767         UPF0767 family
       0.16   12.4   1.1       0.42   11.0   0.0    2.3  2  mono-CXXC       single CXXC unit
       0.18   12.0  26.5      0.038   14.2   4.3    3.8  3  DUF4611         Domain of unknown function (DUF4611)
        5.3    7.1  21.7       0.17   11.9   2.5    3.5  3  RXT2_N          RXT2-like, N-terminal


Domain annotation for each model (and alignments):
>> IQ  IQ calmodulin-binding motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.8   1.5   2.9e-08    0.0001       1      21 []      31      51 ..      31      51 .. 0.94

  Alignments for each domain:
  == domain 1  score: 21.8 bits;  conditional E-value: 2.9e-08
                HHHHHHHHHHHHHHHHHHHHH CS
          IQ  1 rkaaikIQaawRGylaRkryk 21
                ++aa +IQ+++RGy++R+++k
  EEA22100.1 31 ERAAQTIQRYYRGYRTRRELK 51
                59****************986 PP

>> UPF0767  UPF0767 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.6   0.00016      0.56      21      71 ..     485     535 ..     477     548 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00016
     UPF0767  21 aavvGviGynlEsllsdkytpyeksisekRee...Rlleeelnkdvtqveslke 71 
                 a++vG+ Gy     +++k+++ +  i+e+R++   R+ ++++++dv +v++ + 
  EEA22100.1 485 AVLVGIEGYM---KFKQKKKDVKDKIEEERSKianRQQKDQEGEDVPDVSRSRL 535
                 8999999995...689999999********754449999999999999876433 PP

>> mono-CXXC  single CXXC unit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00012      0.42      15      51 ..     134     169 ..     129     176 .. 0.85
   2 ?   -2.5   0.2       1.9   6.7e+03      20      46 ..     513     540 ..     510     549 .. 0.51

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00012
   mono-CXXC  15 dkpaasapdRsrlavDdvkdrvrsSlasdkKtssssv 51 
                  k a +++ R+ ++ D+v+d+v  + +s++K s+s +
  EEA22100.1 134 WKLAGKVALRA-GGDDNVQDKVVEGHVSEEKRSESGT 169
                 567899****9.999999*****************87 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 1.9
   mono-CXXC  20 sapdRsrlavDdv.kdrvrsSlasdkKt 46 
                 + ++R +   +++  + v  S   +kK 
  EEA22100.1 513 KIANRQQKDQEGEdVPDVSRSRLTQKKS 540
                 4555555555555444444444443444 PP

>> DUF4611  Domain of unknown function (DUF4611)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   6.7    0.0014       4.9      59      90 ..      98     127 ..      80     133 .. 0.63
   2 ?   14.2   4.3   1.1e-05     0.038      24      83 ..     303     364 ..     293     377 .. 0.67
   3 ?   -0.1   0.8       0.3   1.1e+03      53      76 ..     509     532 ..     480     563 .. 0.68

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0014
     DUF4611  59 aaagdeeeegededdeeeekniknktksdePp 90 
                 ++++d+e  ++ e++eeee + + +t+ ++P+
  EEA22100.1  98 QHEEDDE--QDQEEEEEEEDKASRRTSQSGPS 127
                 3333333..33344444445668888888987 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 1.1e-05
     DUF4611  24 eadrlksllsgvaqlreevsellst.lveqeaqddvaaagdeeeegededdeeeek.niknk 83 
                 +++r+k  + gv  + ++++ + +   + +e   +  +++d++++ ededdee+e  +i+  
  EEA22100.1 303 DSERFKDSIRGVVPVEDKTPTFREYtKEGNEMLTESSEEDDDDDDAEDEDDEEDEDeEIQRY 364
                 68899999999999999999888762445565555566666666666666666654145544 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.3
     DUF4611  53 eaqddvaaagdeeeegededdeee 76 
                 e++ + a+++++++eged  d + 
  EEA22100.1 509 EERSKIANRQQKDQEGEDVPDVSR 532
                 234445555555555555555555 PP

>> RXT2_N  RXT2-like, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   3.4    0.0082        30      54      87 ..      84     122 ..      46     133 .. 0.55
   2 ?   11.9   2.5   4.9e-05      0.17      45      84 ..     320     360 ..     299     391 .. 0.68
   3 ?    0.6   1.1      0.14   5.2e+02      35      55 ..     510     536 ..     472     576 .. 0.50

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.0082
      RXT2_N  54 k.....kekekeekeeeeedeegdeededdddeeeaeaa 87 
                 +     +++ +   ++ee+de+++ee+e+++d++++++ 
  EEA22100.1  84 TngnvgNDDPEGIIQHEEDDEQDQEEEEEEEDKASRRTS 122
                 134444333333444444444444444444444444444 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 4.9e-05
      RXT2_N  45 npierskrkkkekekeekeeeeedeegdeededdddee.ea 84 
                 ++++ +++ k+++e  ++++ee+d+++d ededd+++e e+
  EEA22100.1 320 KTPTFREYTKEGNEMLTESSEEDDDDDDAEDEDDEEDEdEE 360
                 55566666666666655666666666666665555544222 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.14
      RXT2_N  35 ngserkilsrnpierskrkk.........k 55 
                 + s+   + +++++ ++ ++         +
  EEA22100.1 510 ERSK---IANRQQKDQEGEDvpdvsrsrlT 536
                 1111...11111111111113333333331 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (583 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1798  (0.100284); expected 358.6 (0.02)
Passed bias filter:                      533  (0.0297284); expected 358.6 (0.02)
Passed Vit filter:                        80  (0.00446204); expected 17.9 (0.001)
Passed Fwd filter:                        41  (0.0022868); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.89u 0.34s 00:00:01.23 Elapsed: 00:00:00.50
# Mc/sec: 3505.05
//
Query:       EEA22101.1  [L=545]
Description: allantoate permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.5e-36  126.1  32.7    2.4e-36  125.4  32.7    1.3  1  MFS_1          Major Facilitator Superfamily
    6.8e-08   32.2   4.9    6.8e-08   32.2   4.9    2.3  2  MFS_4          Uncharacterised MFS-type transporter YbfB
    2.1e-06   26.9  16.0     0.0022   16.9   8.1    2.2  2  Sugar_tr       Sugar (and other) transporter
    0.00076   18.4   8.3     0.0012   17.8   8.3    1.4  1  MFS_1_like     MFS_1 like family
  ------ inclusion threshold ------
      0.082   13.0   0.1        0.2   11.8   0.1    1.6  1  Spectrin_like  Spectrin like domain


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  125.4  32.7   6.6e-40   2.4e-36       2     353 .]      59     425 ..      58     427 .. 0.85

  Alignments for each domain:
  == domain 1  score: 125.4 bits;  conditional E-value: 6.6e-40
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfasslwlllvlrvlqGlga 99 
                 + ++fl + + ++lg  ++  l ed g+++s+++l+ ++ ++++++ ++  ++l+ r+ +r ++ + +l+++++ +++++ ++++  llv r++ Gl++
  EEA22101.1  59 MWVYFLQIVDKTVLGYGATFGLREDTGLTGSQYSLVGSISSIAQLAWQPMSSYLIVRVPHRVLMPTLVLGWGISaATMAA-CHNFSGLLVTRFFLGLFE 156
                 6789**************99**************************************9999************444444.5**99************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg.....Wravfyilaivsllafvlfllllpeepperkrkspkeee..... 188
                 ++ +p+  +++a+w+ + e+++ ++l+++++++G ++ ++l+  la+  +     W+ +f++++++++ ++ + ++ll++++ +++r+  +ee+     
  EEA22101.1 157 AGCLPLFSVITAQWYRRAEQPLRVALWYGTNGIGNLFSAALSVGLAHIHShvlrsWQIIFLFVGLLTVASVPM-IFLLLDNDIASARFLNEEEKrmave 254
                 **********************************************88889******************9664.4777777888887777777778888 PP

       MFS_1 189 ........kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallag.rlsdrlgrrrrll 278
                          g  + +++ +w+al  ++  w+++ +++l  +g s + ++ pl+  + +g++   +++ ll +++ v++ + +l+g +l+++++ +  +l
  EEA22101.1 255 rlranqtgTGSREYKWKHVWEALIEPK-TWLFFSMSFLLNVGASVTNIFGPLI-LKGFGFD--SYTTSLLNMPFGVMQTSVILLGcYLAQKTSIKASIL 349
                 888655444445555555888888888.78788888888889999*******7.*******..55555688888888888666661566**99999999 PP

       MFS_1 279 lallllllaalglallavt.ssavllllvlvliGfglgfvfpsllalasdla.ppeeagtasglfntagslggalgp 353
                 lal++ ++a l+++++ +   ++++ll++++l+ f +g  +p++ ++++ ++ ++ ++ ++++ +n a+s+g ++gp
  EEA22101.1 350 LALIAPVVAGLAILYAVPHaGHTAALLVGYYLLAFLFGG-NPLIVSWIVGNTgGATKRSFVASMYNAASSAGNIVGP 425
                 99999888887777665554899999999999***8887.677777777777589********************98 PP

>> MFS_4  Uncharacterised MFS-type transporter YbfB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.2   4.9   1.9e-11   6.8e-08      19     170 ..      80     231 ..      79     260 .. 0.89
   2 ?   -3.4   5.7       1.2   4.5e+03     257     353 ..     318     412 ..     287     423 .. 0.65

  Alignments for each domain:
  == domain 1  score: 32.2 bits;  conditional E-value: 1.9e-11
       MFS_4  19 llaegqlslsqagllaaaNylGYLvGallaafalsagaeRlrllagllatvllllamaltesfaaflliRflaGvasAvvlvfgsslvlahaaaarrer 117
                 l+++++l+ sq +l++++  +  L+   + ++   + ++R+ +   +l   +++++ma+ ++f+ +l+ Rf +G+  A  l + s +  +    a+++ 
  EEA22101.1  80 LREDTGLTGSQYSLVGSISSIAQLAWQPMSSYLIVRVPHRVLMPTLVLGWGISAATMAACHNFSGLLVTRFFLGLFEAGCLPLFSVITAQWYRRAEQPL 178
                 6789999******************999999**********999999999************************************************* PP

       MFS_4 118 vgallfaGvGlGiavsgllvllllqlglsasslWlalavlsavllllvalllp 170
                   al ++  G+G + s+ l + l + + +   +W+++ ++  +l++++++++ 
  EEA22101.1 179 RVALWYGTNGIGNLFSAALSVGLAHIHSHVLRSWQIIFLFVGLLTVASVPMIF 231
                 *****************************9999***99999999999988765 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 1.2
       MFS_4 257 ralaaallieavgvllsllspsplglivssvllGltflaitalvlqlarelappatrrllglmTasfgigQilGpllasllaeatgslalallvaaa 353
                  +l + + +   +v+l     +    i +s+ll l   ++  l++ +a   a+++   l+g   ++f  g    pl++s++   tg+ +  ++va+ 
  EEA22101.1 318 SLLNMPFGVMQTSVILLGCYLAQKTSIKASILLALIAPVVAGLAILYAVPHAGHTAALLVGYYLLAFLFGG--NPLIVSWIVGNTGGATKRSFVASM 412
                 55555554444444444444444455666666666666666666666666666666666666666666663..588888888888888888888875 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   8.1   6.3e-07    0.0022      45     321 ..      88     349 ..      69     354 .. 0.79
   2 !   16.9   2.4   6.4e-07    0.0023      67     161 ..     336     431 ..     333     516 .. 0.69

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 6.3e-07
                 ..HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTT...S-SCCHHHHH CS
    Sugar_tr  45 svlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEi...ApkklRgalv 140
                  ++++l+ si ++ +++ + ++++l+ r+  +  + + ++   i+a+ +aa++   ++  l+v R+++G++  ++  l ++ ++     A + lR al 
  EEA22101.1  88 GSQYSLVGSISSIAQLAWQPMSSYLIVRVPHRVLMPTLVLGWGISAATMAACH---NFSGLLVTRFFLGLFEAGCLPLFSVITAQWyrrAEQPLRVALW 183
                 468999999999999999***********************************...*************998888888888887762225566665555 PP

                 HHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHHTT-HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH... CS
    Sugar_tr 141 slyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPrylvekgkeeeakevlaklrgeedadrelaeekdsleaeqeeek 239
                         +G l++a + +gl+++++    ++l   q+++    +++ll++   P  ++  +++ ++ ++l +     +++r ++e  ++++ +  +++
  EEA22101.1 184 YG---TNGIGNLFSAALSVGLAHIHS----HVLRSWQIIFL---FVGLLTVASVPMIFLLLDNDIASARFLNE-----EEKRMAVERLRANQTGTGSRE 267
                 55...4579*****************....56666665544...44444444444444445666788888888.....888888888888888877778 PP

                 ..HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH..HHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHH CS
    Sugar_tr 240 aswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsks..llvtiivgvvnfvatfvaiflvdrfGRRtlll 321
                  +wk +++      + +  +  ++f   +G  +  +++p i++  g++     l ++ +gv+++ +++ + +l  +++ +   l
  EEA22101.1 268 YKWKHVWEA--LIEPKTWLFFSMSFLLNVGASVTNIFGPLILKGFGFDSYttSLLNMPFGVMQTSVILLGCYLAQKTSIKASIL 349
                 899999999..55666677777777777899*****************99999*********************9998776555 PP

  == domain 2  score: 16.9 bits;  conditional E-value: 6.4e-07
                 HHHHHHTTHHHHHHH.HHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Sugar_tr  67 gllgdrfGRkkslli.aavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglgl 161
                  +l+++ + k s+l   ++ +v+g ++ +a +++ ++ +l+vg  l+ +  G+   +v+  ++    +++R+++ s+y+ a ++G +v+  +    
  EEA22101.1 336 CYLAQKTSIKASILLaLIAPVVAGLAILYAVPHAGHTAALLVGYYLLAFLFGGNPLIVSWIVGNTGGATKRSFVASMYNAASSAGNIVGPLLFNSK 431
                 5666777777777662444456666677777777******************************************************98766554 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   8.3   3.3e-07    0.0012     107     302 ..     138     357 ..      14     437 .. 0.76

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 3.3e-07
  MFS_1_like 107 aektfwilfllvvlasfflaailvlldaatlkelgedrkdyGrqrlfGsvGya.ifafitGilidhysvnllp.ysallyvlaallvisllvvlilnet 203
                 a ++f  l++ +++  +f a+ l+l+ ++t ++ +  ++       +G+ G + +f++++++ + h++ ++l+  + +++++ +l v+s+ ++  l + 
  EEA22101.1 138 ACHNFSGLLVTRFFLGLFEAGCLPLFSVITAQWYRRAEQPLRVALWYGTNGIGnLFSAALSVGLAHIHSHVLRsWQIIFLFVGLLTVASVPMIFLLLDN 236
                 6689999***************************9999988778888999987699****************975556666666677777665554444 PP

  MFS_1_like 204 ekesklkvtksl.......................qvllnilknpeviifllvalilgmswgiienFlflYLkelgasntllGsl.valgvvaeiplff 278
                   +s+  + + +                       +++++ l +p+ ++f+ + ++l +  ++ + F  l Lk  g+ +++ + l +++gv+ +  + +
  EEA22101.1 237 DIASARFLNE-EekrmaverlranqtgtgsreykwKHVWEALIEPKTWLFFSMSFLLNVGASVTNIFGPLILKGFGFDSYTTSLLnMPFGVM-QTSVIL 333
                 4444433333.24779999****************99**********************************************983566655.555666 PP

  MFS_1_like 279 faeklleklGhvklliiallayil 302
                 ++ +l +k+++   +++al+a ++
  EEA22101.1 334 LGCYLAQKTSIKASILLALIAPVV 357
                 778999999999999999987655 PP

>> Spectrin_like  Spectrin like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.1   5.6e-05       0.2      34      65 ..     484     515 ..     474     525 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 5.6e-05
  Spectrin_like  34 knLelhyqdFlrdSqeSelFteedrkqlerev 65 
                    ++++ hy+dF +d + S++ ++ +r++ ++  
     EEA22101.1 484 HSMQKHYHDFAEDNKPSNMVEQVERTETQQTT 515
                    589*********************99988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (545 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       731  (0.0407719); expected 358.6 (0.02)
Passed bias filter:                      430  (0.0239835); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.64u 0.32s 00:00:00.96 Elapsed: 00:00:00.51
# Mc/sec: 3232.91
//
Query:       EEA22102.1  [L=504]
Description: hypothetical protein PMAA_058820 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
     0.0027   16.4   0.0      0.038   12.7   0.0    2.1  1  Transferase  Transferase family


Domain annotation for each model (and alignments):
>> Transferase  Transferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   0.0   2.1e-06     0.038     131     372 ..     145     403 ..     115     411 .. 0.68

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.1e-06
  Transferase 131 ipllavqvTkfkcGgvalgvsvsHaiaDgaSlktfieswaelargekkvtvtplfarelllprpeppsvefdqlelrkfsasettevkevvtkkivle 228
                   pll v    + +   ++   + H  aD +++ +++++w ela ++  + + + +++  ++ +  +   e+++ e   + ++ +t++++  +  +v++
   EEA22102.1 145 APLLYVHLSLYTDA-TVIALGLPHVLADQMGVANIMRAWFELAYKNTTPPEMIGYNEDIFQTPTTKKYAEYPHNE---IYRKGKTKLRNGWEYIFVIM 238
                  57777777766666.678888899999999999999999999999988888888888888777333333444444...44444444444444444444 PP

  Transferase 229 klsaskleeLkkkasdesngk........................pa..trfesvtallWrcavkarkldesketvlgiavdiRsr...le.pklpee 296
                        l eL     + ++                           +  ++ + v+a l +  + a k+++  + +l ++v++R r   l  p+ +++
   EEA22102.1 239 ----GFLPELIFNRTERQHIVffpmpmldglkeryrkeltaqygaDPglSTGDIVSAILTKFSRMADKKNR--TLTLSQLVNLRGRhpnLTsPEKQRS 330
                  ....3333333333333333333334444444444444444344444679999999999999888877765..679********994443359999** PP

  Transferase 297 yfGNallsvvvkstakellseelsrivekvkeavkkaitkeylsseidweenstlkaelvskgkkdgeevtvsswl 372
                  y+ Nall v++   +k     ++  i+ ++ +a++    +e+  +++   e+  +   + +  +++  ++ v+ w+
   EEA22102.1 331 YIHNALLYVSARFPIKP--TTPVCEIAYQNRQAIASCTLEEIEIVQAVMREQVRIGQATHICEPFE-MSYFVTNWC 403
                  ******99999888875..67899999999999999888888888877777765554444444555.688999888 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (504 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       896  (0.0499749); expected 358.6 (0.02)
Passed bias filter:                      636  (0.0354733); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.44
# Mc/sec: 3404.13
//
Query:       EEA22103.1  [L=1027]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.8e-36  124.4   0.0    2.3e-18   66.2   0.0    2.3  2  Cupin_1         Cupin
    2.3e-21   75.2   0.3    1.9e-11   43.5   0.0    2.7  2  Cupin_2         Cupin domain
    4.7e-07   29.4   0.0      0.005   16.5   0.0    2.5  2  Cupin_3         Protein of unknown function (DUF861)
     0.0012   18.7   0.1        1.5    8.8   0.0    2.6  2  AraC_binding    AraC-like ligand binding domain
     0.0022   18.1   3.9     0.0037   17.4   3.9    1.3  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.062   12.1   0.1      0.084   11.7   0.1    1.3  1  Fungal_trans_2  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Cupin_1  Cupin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.7   0.0   1.3e-18     4e-15      10     146 ..     130     260 ..     123     263 .. 0.87
   2 !   66.2   0.0   7.7e-22   2.3e-18       3     114 ..     302     410 ..     300     443 .. 0.85

  Alignments for each domain:
  == domain 1  score: 55.7 bits;  conditional E-value: 1.3e-18
                 EEETTEEEEEESTTTSTTTHSSTEEEEEEEE.TTEEEEEEEESSS-EEEEEEESEEEEEEEETTSS.EEEEEEEETTEEEEE-TT-EEEEEEESSSSEE CS
     Cupin_1  10 ieseggrvteansenlpglntlgisaarvdlepgglllPhyhpnateiayvlqGegrvgfvvpgngnrdfhkklreGdvfvvPaglvhfqynsgdepav 108
                    egg++++ + ++lp+ + l+++  r+d   g ++++h+h + +e+a++l G++rv  + ++    +f  ++++Gd+++ Pag++h ++    + + 
  EEA22103.1 130 RIEEGGWTRQTTIRELPTSKELAGVNMRLDE--GVIRELHWH-SEAEWAFMLAGKARVTGLDTDG--GSFIDDVEAGDLWYWPAGHPHSIQGLSPNGTE 223
                 4459*************88888887777776..*********.9**************9999999..8*************************845555 PP

                 EEEEEESSSTT-EEHSCEHHHHHTSSBHHHHHHHHTSS CS
     Cupin_1 109 aivvfdtnnpgnqsvlaalfsvlpaLdrevlakafqla 146
                  + +fd+ n  ++s+++  ++++++ +++vl ++f++ 
  EEA22103.1 224 FLLIFDDGNFSEESTFLVTDWMAHT-PKSVLSENFGIP 260
                 5567888889999999999******.*********986 PP

  == domain 2  score: 66.2 bits;  conditional E-value: 7.7e-22
                 CGGSSEEEEETTEEEEEESTT.TSTTTHSSTEEEEEEEE.TTEEEEEEEESSS-EEEEEEESEEEEEEEETTSS.EEEEEEEETTEEEEE-TT-EEEEE CS
     Cupin_1   3 llepsptieseggrvteanse.nlpglntlgisaarvdlepgglllPhyhpnateiayvlqGegrvgfvvpgngnrdfhkklreGdvfvvPaglvhfqy 100
                  l ++pti+s gg v+  +s+ n+p     +++aa + l+pg+l+++h+hpna e+ y + G++r ++v+ ++g + ++ ++ +Gdv +vP+++ hf+ 
  EEA22103.1 302 MLAQEPTINSTGGEVRITDSKtNFP--ISDRVAAAHLKLQPGALREMHWHPNADEWSYFIRGRAR-VTVFAAEG-NARTFDYMAGDVGIVPKNMGHFVE 396
                 68899***********999983566..8999**********************************.66666653.788889****************** PP

                 EESSSSEEEEEEEE CS
     Cupin_1 101 nsgdepavaivvfd 114
                 n  d++ ++   + 
  EEA22103.1 397 NLSDDEPLEMLEIF 410
                 *9988877766555 PP

>> Cupin_2  Cupin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.2   0.1   1.8e-10   5.4e-07       3      70 ..     156     227 ..     154     228 .. 0.84
   2 !   43.5   0.0   6.3e-15   1.9e-11       3      71 .]     336     410 ..     334     410 .. 0.90

  Alignments for each domain:
  == domain 1  score: 29.2 bits;  conditional E-value: 1.8e-10
                 EEEETTEEEEEECSSSEEEEEEEEESEEEEE.ECTE....EEEEETTEEEEE-TT-EEEEEE-SSS-EEEEEE CS
     Cupin_2   3 velppGesapshrHpgedeffyVleGegelt.vdge....eveleaGdsvyfpagtpHrfrNtgdeparllvv 70 
                 ++l+ G   + h+H+++ e+ + l G++++t +d        ++eaGd++y pag pH +   +    ++l +
  EEA22103.1 156 MRLDEGVIRELHWHSEA-EWAFMLAGKARVTgLDTDggsfIDDVEAGDLWYWPAGHPHSIQGLSPNGTEFLLI 227
                 6677888899*******.****************444567778***************998777776666665 PP

  == domain 2  score: 43.5 bits;  conditional E-value: 6.3e-15
                 EEEETTEEEEEECSSSEEEEEEEEESEEEEE.ECTE....EEEEETTEEEEE-TT-EEEEEE-SSS.-EEEEEEE CS
     Cupin_2   3 velppGesapshrHpgedeffyVleGegelt.vdge....eveleaGdsvyfpagtpHrfrNtgde.parllvvy 71 
                  +l+pG+  ++h+Hp++de+ y ++G++++t    e    ++++ aGd+ ++p+++ H ++N +d+ p+++l ++
  EEA22103.1 336 LKLQPGALREMHWHPNADEWSYFIRGRARVTvFAAEgnarTFDYMAGDVGIVPKNMGHFVENLSDDePLEMLEIF 410
                 679****************************555334477**********************99999*****996 PP

>> Cupin_3  Protein of unknown function (DUF861)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.1   0.0   0.00016      0.49      25      60 ..     171     210 ..     165     221 .. 0.82
   2 !   16.5   0.0   1.7e-06     0.005      18      60 ..     345     391 ..     328     399 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00016
                 SEEEEEEEECEEEEEET...TTEE.EEEETTEEEEE-TTE CS
     Cupin_3  25 edEfcyileGevkvtpe...gget.velraGDlvvlpkgl 60 
                 e E +++l G+ +vt     gg+    ++aGDl++ p+g 
  EEA22103.1 171 EAEWAFMLAGKARVTGLdtdGGSFiDDVEAGDLWYWPAGH 210
                 5799**********9654536666568***********95 PP

  == domain 2  score: 16.5 bits;  conditional E-value: 1.7e-06
                 EEEECESSEEEEEEEECEEEEEET..TTEE..EEEETTEEEEE-TTE CS
     Cupin_3  18 kfrltyeedEfcyileGevkvtpe..gget..velraGDlvvlpkgl 60 
                 + +++  +dE  y+++G+ +vt+   +g++  + + aGD+  +pk++
  EEA22103.1 345 EMHWHPNADEWSYFIRGRARVTVFaaEGNArtFDYMAGDVGIVPKNM 391
                 468***************999987677777668889********987 PP

>> AraC_binding  AraC-like ligand binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.8   0.0   0.00049       1.5      18      62 ..     166     215 ..     159     225 .. 0.86
   2 !    7.1   0.0    0.0016       4.8      16      69 ..     344     404 ..     334     460 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00049
                   EETT-SEEEEEEEEE-EEEEETTEE.....EEE-TT-EEEE-TTS-EEEE CS
  AraC_binding  18 phvhdeyvihyvteGtgrlrlngrt.....ydlgpGdlfLlppgepHdye 62 
                    h+h+e+++  +++G++r++  +        d+++Gdl   p g+pH+++
    EEA22103.1 166 LHWHSEAEWAFMLAGKARVTGLDTDggsfiDDVEAGDLWYWPAGHPHSIQ 215
                   5*****************97655555667779***************987 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0016
                   EEEETT-.SEEEEEEEEE-EEEEE.....TTEEEEE-TT-EEEE-TTS-EEEEE-TTS.EE CS
  AraC_binding  16 fpphvhd.eyvihyvteGtgrlrl.....ngrtydlgpGdlfLlppgepHdyesdsed.gw 69 
                    + h+h+   ++ y+++G++r+++     n rt+d  +Gd+ ++p+++ H+ e  s+d ++
    EEA22103.1 344 REMHWHPnADEWSYFIRGRARVTVfaaegNARTFDYMAGDVGIVPKNMGHFVENLSDDePL 404
                   577****5559*********9964333335566******************9988876555 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   3.9   1.2e-06    0.0037       9      32 ..     488     511 ..     486     516 .. 0.91

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 1.2e-06
                 CT---STSSSS-HHHHHCTHHHCC CS
     Zn_clus   9 kKvKCdakkPaCsnCkklnleCtf 32 
                 ++vKCd+ +P+C +C + + +C  
  EEA22103.1 488 RRVKCDKVRPNCNRCSSTGRKCDG 511
                 89********************75 PP

>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.1   2.8e-05     0.084       3      58 ..     538     592 ..     536     899 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 2.8e-05
  Fungal_trans_2   3 ldyyldnvapllspvpessnpfrkvllplalsnkallhallalsafhlqskgpkds 58 
                     ++++ ++++p l  ++ s   +   +l+l +++k+++ha++al+++h +   +++ 
      EEA22103.1 538 FQFFYERTVPALAGISGS-IFWNIFVLQLSQHEKSVWHAIIALGSLHEKFVEKEQN 592
                     677778888855555554.589999**********************966655554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1027 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      451  (0.0251548); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.70u 0.30s 00:00:01.00 Elapsed: 00:00:00.44
# Mc/sec: 6975.82
//
Query:       EEA22104.1  [L=284]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.9e-45  153.0  11.1    1.1e-44  152.7  11.1    1.1  1  DUF1275        Protein of unknown function (DUF1275)
  ------ inclusion threshold ------
        0.4   10.6   4.4       0.13   12.1   0.7    2.1  2  7TMR-DISM_7TM  7TM diverse intracellular signalling


Domain annotation for each model (and alignments):
>> DUF1275  Protein of unknown function (DUF1275)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  152.7  11.1   1.2e-48   1.1e-44       2     191 ..      45     267 ..      44     268 .. 0.85

  Alignments for each domain:
  == domain 1  score: 152.7 bits;  conditional E-value: 1.2e-48
     DUF1275   2 llllafvaGllDavaflaaggvfvsaqTGNtvllglalaegna..............kaalaalvsllaFvlGaalagllarrggrrrrlvllle.... 82 
                 ll +++++GllD+ a+   +g fvs+qTGNtv+lgl+la+++               + ++ +++s+++F+lG++++g ++r++++r+r+vl+++    
  EEA22104.1  45 LLYCYIITGLLDSSAV-FIWGSFVSMQTGNTVYLGLGLASQAShpkksgagsgsgndDRWIKSGISIISFCLGSLIFGAFHRAFSPRKRWVLMASsalq 142
                 899*************.6*******************654322333333334444336666688****************988899************9 PP

     DUF1275  83 allllaaallvpagsvsp.........lalallafamGlqnalfsr.lsgaeitttvlTgnltdlgidlarll....kkrklarnrrlaiilafllGav 167
                 ++++++aa +v+  ++s+         ++la++af++++q+++ sr l+ ++++++vlT++++dl++++  l     +k+  + +rr+++++++l+Gav
  EEA22104.1 143 MICITCAATIVTMERPSKdsaltwrviVPLAMVAFQSSGQAVI-SRvLKLGGLSSVVLTSVYCDLFSHPDFLSgvafRKD-VEERRRAGAVVCLLAGAV 239
                 9999999999886655449*******99***************.999********************9554444433333.44899************* PP

     DUF1275 168 vGallvks....aaalwlaaallllval 191
                 +G+++++s    ++alw+a++l+++++l
  EEA22104.1 240 MGGFWARSevglMGALWTAVGLKAVIVL 267
                 *************************987 PP

>> 7TMR-DISM_7TM  7TM diverse intracellular signalling
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.7   1.5e-05      0.13      59     120 ..      99     160 ..      64     206 .. 0.77
   2 ?   -0.8   0.3      0.13   1.2e+03     103     150 ..     232     277 ..     174     279 .. 0.59

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 1.5e-05
  7TMR-DISM_7TM  59 nappalnnkllyltlllllilfllFarsflelkkkprllklllllavllsllllllpll..pyt 120
                    n + ++ + + +++++l++++f +F r f  +k+  ++l +  +l ++++ +++++  +  p +
     EEA22104.1  99 NDDRWIKSGISIISFCLGSLIFGAFHRAFSPRKR--WVLMASSALQMICITCAATIVTMerPSK 160
                    5566999999*******************99966..9999999999997777777444433222 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.13
  7TMR-DISM_7TM 103 lavllsllllllpllpyteslslaqllallvillllligikawrkgnk 150
                    +++l+++++    ++  +e+  +  l +++++  +++++   wr+g++
     EEA22104.1 232 VCLLAGAVMG--GFWARSEVGLMGALWTAVGLKAVIVLAWCFWRRGDR 277
                    3333222222..233333333333344444444445555555566665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (284 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       571  (0.0318478); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 1983.67
//
Query:       EEA22105.1  [L=409]
Description: aspergillopepsin F precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.1e-46  158.8   0.0    2.4e-46  158.6   0.0    1.0  1  Asp             Eukaryotic aspartyl protease
  ------ inclusion threshold ------
       0.02   15.5   0.1         12    6.6   0.0    3.4  4  Asp_protease_2  Aspartyl protease


Domain annotation for each model (and alignments):
>> Asp  Eukaryotic aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  158.6   0.0   2.7e-50   2.4e-46       1     313 [.     102     406 ..     102     408 .. 0.91

  Alignments for each domain:
  == domain 1  score: 158.6 bits;  conditional E-value: 2.7e-50
                 EEEEEEEETTTTEEEEEEEETT--SEEEEBTTESTSHCHHTSS-B-GGG-TT-EEEEEEEEEECTTS.EEEEEEEEEEEEETTEEEEEEEEEEEEEESS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp   1 eYfgeisiGtpeqkftvifDTGSsdlWVpsskckkssackshstydpskSstykkngkslsisYGdg.svsGflsqdtvkvggltvknqefgeatkepg 98 
                 +Y  ++++G    ++t++fDTG sdlWV+ ++++      sh+ +d+  S+     g++++is+G+   ++G +  d+v+vgg+t ++q++++a + ++
  EEA22105.1 102 QYHMPVKLGNI--NMTLMFDTGNSDLWVTINETQ---GRGSHHPFDN--STCLPLPGYTFDISWGSFgDITGDVCSDKVEVGGITSQKQAIQLALHLSE 193
                 68888888876..899*************99998...6788888875..788889***********88******************************* PP

                 HHHTTSSSSEEEE-S-GGGSCGG...SCCHHHHHHHTTSSSSSEEEEEE-STTSSEEEEEESSEEGGGEEEEEEEEEESS.TSSTEEEEEEEEETTEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxx RF
         Asp  99 stflaakfdGiLGlgfkeisvee...atpvfdnlvsqglikepvfsvylnreeeeggeivfGgvDeskykGsltyvpvts.kgywqielesvtvggktv 193
                 +   + k+dG++G +f  ++  e   +++ f+n+++   +++pvf+v l   ++++g+i fG vD++k +Gs+++  v++ +g+w++  e++ +g+++v
  EEA22105.1 194 HISGSIKDDGVMGFSFIGLNNIEpkpQNTWFENVKNS--LQKPVFTVDLR--KNAVGTIDFGFVDPKKHRGSIFWAYVDEkSGFWRFYNEGYIIGNDSV 288
                 *************999887777745477779998776..**********5..999***********************99799***************9 PP

                 EEEEEEEEEEETTCSSEEEEHHHHHHHHHHH.TTEEEETTCEEEEETTGGGGSEEEEEEETTEEEEEEGGGGEEEESSSTTSEEEESEEECCTSSSEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp 194 lcssgcqailDtGTsllalptsivekiakai.gakksesegeyvvdCdslsslpdisftiggakitvpvselvlkeeeseesqCilglvseeegdlwiL 291
                    + +  ilDtG +++ l + +ve++ +++ ga  +e ++ yv+ C++  +lp+ ++ ++ a++tvp  ++ + +    ++ C+ g++s+ + +  i 
  EEA22105.1 289 -IGDFFPGILDTGGNMILLFDPMVEEYYNKVpGAFFDEGNEGYVFPCNA--TLPNWTVIVEKARFTVPGPNINFAPVG--SGLCYGGIQSNGGLPFAIY 382
                 .8899*********************9999835556777899******8..***********************9995..579**************** PP

                 EHHHHTTEEEEEETTTT..EEEEE CS
                 xxxxxxxxxxxxxxxxx..xxxxx RF
         Asp 292 GdvFlrsayvvfdldnn..rvglA 313
                 G++F++++ ++f   n+  rvg+A
  EEA22105.1 383 GNLFISQFLTIFGAYNKfpRVGFA 406
                 ************988854589998 PP

>> Asp_protease_2  Aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       1.6   1.4e+04      48      74 ..      74     100 ..      65     102 .. 0.76
   2 ?    6.6   0.0    0.0013        12       2      24 ..     106     128 ..     105     143 .. 0.87
   3 ?    1.1   0.0     0.071   6.4e+02      57      90 .]     169     209 ..     159     209 .. 0.76
   4 ?    3.0   0.0     0.018   1.6e+02      13      32 ..     296     315 ..     288     322 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 1.6
  Asp_protease_2  48 ggevkarlvrldslklggltlknvpal 74 
                     gg+v+++l  l + + g++ +++ p++
      EEA22105.1  74 GGRVSKKLRSLANPQTGSVNVTSYPFY 100
                     778888888888888888888888776 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0013
  Asp_protease_2   2 pvtinGkpvrfllDTGasttlis 24 
                     pv++++  +++++DTG s + ++
      EEA22105.1 106 PVKLGNINMTLMFDTGNSDLWVT 128
                     8999999***********98776 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.071
  Asp_protease_2  57 rldslklggltlknvpalvld.......lgeeidglLGmdf 90 
                       d++++gg+t + +++  +        +  ++dg++G++f
      EEA22105.1 169 CSDKVEVGGITSQKQAIQLALhlsehisGSIKDDGVMGFSF 209
                     56899999999999986555556677755568899999987 PP

  == domain 4  score: 3.0 bits;  conditional E-value: 0.018
  Asp_protease_2  13 llDTGasttlispelaeklg 32 
                     +lDTG +++l+ + ++e+  
      EEA22105.1 296 ILDTGGNMILLFDPMVEEYY 315
                     89***********9999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (409 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       346  (0.0192983); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2679.13
//
Query:       EEA22106.1  [L=992]
Description: reverse transcriptase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-35  122.4   0.0    2.8e-35  121.8   0.0    1.2  1  RVT_1     Reverse transcriptase (RNA-dependent DNA polymerase
    8.6e-11   42.2   0.0    1.8e-10   41.2   0.0    1.5  1  RNase_H   RNase H
    2.2e-05   25.1   0.0    6.5e-05   23.6   0.0    1.7  1  zf-RVT    zinc-binding in reverse transcriptase
  ------ inclusion threshold ------
       0.08   12.8   0.2        0.3   10.9   0.0    2.1  3  RVT_3     Reverse transcriptase-like


Domain annotation for each model (and alignments):
>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.8   0.0   6.3e-39   2.8e-35       3     222 .]     216     475 ..     214     475 .. 0.92

  Alignments for each domain:
  == domain 1  score: 121.8 bits;  conditional E-value: 6.3e-39
                 -TT.......S-EEE......-THHHHCTB--...........-------HHHH................HCCHTS--EEEEEEBCCGCCCSBB-GGGG CS
       RVT_1   3 Kkg......pgsyRpisllsvdykalnkliakrLkdvl..ekllsenqpgfrpgrstldav...edllkalkkkkkaklllklDlkkaFdsvpleellr 90 
                 K+g      ++ yR+isll++++k+++kl+a  ++d++  + l++++q+g r++rs +dav       ++++ ++k   +l++D+k+aFd v +++l+ 
  EEA22106.1 216 KPGkgiytvAKAYRIISLLKCLGKVVEKLVAGLITDYAeaQGLFHKSQFGARRQRSAVDAVaclIGEIEHAWGNGKLGACLFMDIKGAFDYVVWSKLIG 314
                 666667778899**************************9999*******************9995555556999************************* PP

                 GGG-EEET.........................TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T......TEEECTTEEEEEESSHHH......HHHH CS
       RVT_1  91 kltafkvptklinliksflstrsfsvrvngeeskgryekkglpqGsvlSPllfnlfmnellrelrkrakgvtllrYaDDililskskee......lqel 183
                  l+  +++  l++++ s+  +r++ + ++g+  ++ +++ glpqGs++SP+lf l++  l   +++++++v  l ++DD  +++   +       lq++
  EEA22106.1 315 GLQGTGMDGDLVRWVASMS-NRRAMLVIDGHIGEEVPISSGLPQGSPVSPILFVLYVRLLVAAIESAVPEVRGLSFVDDQGLVTAASSIreacktLQHA 412
                 *****************98.99989999***55**********************************************7766666555568******* PP

                 HHHHHHHHHHTT--BEGGG-EEE.............................ESSEEETTEEE CS
       RVT_1 184 leaveewlkesglkinpeKtklvlft.......................v.kseevkyLGvtl 222
                  ++  +w  e+g+++ p+Kt+++ ft                       +  +++v++LGv+l
  EEA22106.1 413 AKVAIKWGVENGVQFDPSKTEAAFFTrqreslfrrnirearitvggvraKiMPNTVRWLGVIL 475
                 ***********************999*********9999999999987537999999999975 PP

>> RNase_H  RNase H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.2   0.0     4e-14   1.8e-10       5     142 ..     692     823 ..     689     824 .. 0.75

  Alignments for each domain:
  == domain 1  score: 41.2 bits;  conditional E-value: 4e-14
                 EEEEEEEEECTTTCE.EEEE.EECTT..EEEEEEECCCCHHHHHHHHHHHHHHH.TT.SC..SEEEEEES-HHHHHHHHCCCHHHHHTTSSSETTSSBH CS
     RNase_H   5 vvYtDGsclgnpgeg.gaga.vlykegarnisapleeaqtnnraELsAvieaLk.alksd..ekvniytDSkYvvkgitqwvhrwkknawkttseqkpv 98 
                  +++DGs ++n ++g g+++ ++++  +++++ p+         EL+ v  aL+ al+++    +++  D ++++k +++   +    ++  +      
  EEA22106.1 692 ALWSDGSRQNNGRTGaGVALqIVPEAPWEHLELPMGTGFEVFDVELMGVASALEwALERHlpGPIHVLLDAQNAIKRLQS---TEPGAGQSLALR---- 783
                 5799***777766666666656665547788888887788899**************99988899***********6655...222233333333.... PP

                 TTHHHHHHHHHCHCSSEEEEEE-SCCSSSTHHHHHHHHHHHHHH CS
     RNase_H  99 knkdlaellkelakkkkvqlkwvkgHaGvpkgNemaDrlAkeaa 142
                  ++  a +l    + + v+++wv+gH+Gv +gNe+aD++Ak+aa
  EEA22106.1 784 -ARMAASRL--RLSGRPVTIQWVPGHNGV-EGNEQADQAAKRAA 823
                 .33334444..456899************.7**********998 PP

>> zf-RVT  zinc-binding in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.6   0.0   1.5e-08   6.5e-05      26      79 ..     857     910 ..     838     913 .. 0.89

  Alignments for each domain:
  == domain 1  score: 23.6 bits;  conditional E-value: 1.5e-08
      zf-RVT  26 skappkvkfflWlllknrlptadnllkrgiesssrCqlCgqeeEtieHlfleCp 79 
                 +kap +v    + l +++ p+   l++ +   s++C  Cg+  Et++H+++eC+
  EEA22106.1 857 AKAPKRVASRYYQLKTGHAPIGTYLHRIKTRDSPECRACGELRETVSHILFECR 910
                 678999999999999**************************************6 PP

>> RVT_3  Reverse transcriptase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0       2.1   9.3e+03      29      57 ..     258     288 ..     248     290 .. 0.70
   2 ?   -3.1   0.0       1.4   6.4e+03      19      53 ..     389     422 ..     386     423 .. 0.78
   3 ?   10.9   0.0   6.8e-05       0.3       7     124 .]     699     822 ..     695     822 .. 0.81

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 2.1
       RVT_3  29 agaek.lqgkasveeAElqALlrG.Lqlalk 57 
                  ++++ ++ + +++ +++ A+l+G +++a+ 
  EEA22106.1 258 LFHKSqFGARRQRSAVDAVACLIGeIEHAWG 288
                 4555557888888888888888887777776 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 1.4
       RVT_3  19 irdsnGevllagaeklqgkasveeAElqALlrGLq 53 
                 ++d++G v++a++ + + + + ++A   A+ +G++
  EEA22106.1 389 FVDDQGLVTAASSIR-EACKTLQHAAKVAIKWGVE 422
                 568888888888888.8888888888888888875 PP

  == domain 3  score: 10.9 bits;  conditional E-value: 6.8e-05
       RVT_3   7 kkksgaggagvvirdsnGevllagaeklqgkasveeAElqALlrGLqlalklgirr.lvvegDsktvvqllngrekvksselanlldeirkllk.sfes 103
                 ++++g++gagv++           + +++++++v+ +El+++  +L+ al++ +   ++v  D +  ++ l++ e+   + la   + + + l+ s + 
  EEA22106.1 699 RQNNGRTGAGVALQIVPEAPWEHLELPMGTGFEVFDVELMGVASALEWALERHLPGpIHVLLDAQNAIKRLQSTEPGAGQSLALRARMAASRLRlSGRP 797
                 466677777777766666566666777999*********************999855*******************88888888888888888889999 PP

       RVT_3 104 vsvehip....ReqNrvAdalAkra 124
                 v+++++p     e+N  Ad++Akra
  EEA22106.1 798 VTIQWVPghngVEGNEQADQAAKRA 822
                 9999998444458999999999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (992 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       355  (0.0198003); expected 358.6 (0.02)
Passed bias filter:                      303  (0.0169); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.67u 0.29s 00:00:00.96 Elapsed: 00:00:00.48
# Mc/sec: 6211.15
//
Query:       EEA22107.1  [L=166]
Description: hypothetical protein PMAA_058870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (166 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1075  (0.0599587); expected 358.6 (0.02)
Passed bias filter:                      586  (0.0326845); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.47u 0.29s 00:00:00.76 Elapsed: 00:00:00.46
# Mc/sec: 1086.25
//
Query:       EEA22108.1  [L=89]
Description: hypothetical protein PMAA_058880 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (89 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       210  (0.0117129); expected 358.6 (0.02)
Passed bias filter:                      184  (0.0102627); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.27s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 632.19
//
Query:       EEA22109.1  [L=535]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.4e-31  107.0   2.4    2.4e-09   37.6   0.4    4.9  5  Ank_2     Ankyrin repeats (3 copies)
    9.4e-27   93.0   1.3    0.00046   20.7   0.0    7.6  7  Ank_4     Ankyrin repeats (many copies)
    6.8e-21   74.1   8.3      5e-06   26.7   0.2    6.9  8  Ank_5     Ankyrin repeats (many copies)
      3e-20   70.2  10.9    0.00054   20.2   0.4   10.4 11  Ank_3     Ankyrin repeat
    1.2e-16   60.2  19.4    4.3e-05   23.8   0.9    9.2  9  Ank       Ankyrin repeat
  ------ inclusion threshold ------
      0.015   15.6   0.8      0.033   14.5   0.1    1.9  2  PRANC     PRANC domain


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.0      0.11   3.4e+02      51      80 ..     112     141 ..      56     143 .. 0.69
   2 !   24.1   0.1   1.3e-08   3.9e-05      21      81 ..     180     240 ..     164     242 .. 0.81
   3 !   37.6   0.4   8.1e-13   2.4e-09       1      83 []     186     275 ..     186     275 .. 0.86
   4 !   32.9   0.0   2.4e-11   7.3e-08       1      80 [.     282     378 ..     282     381 .. 0.85
   5 !   29.6   0.0   2.7e-10     8e-07       3      83 .]     390     479 ..     388     479 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.11
       Ank_2  51 ndgrtpLhyAarsghleivklLlekgadin 80 
                  +g   L  A  + ++++++l++e ga +n
  EEA22109.1 112 PSGILLLNEAMVCERIDLCQLFIEAGARVN 141
                 6677779999999999*******99*9998 PP

  == domain 2  score: 24.1 bits;  conditional E-value: 1.3e-08
       Ank_2  21 dpnkngktaLhyAakngnleivklLleh.ad......ndgrtpLhyAarsghleivklLlekgadinl 81 
                 dp+     +Lh+Aa+ +nleiv lLl+h a+      ++g +pLh+   +++ +i++ L+ kga++n+
  EEA22109.1 180 DPD---FEPLHLAAIVDNLEIVDLLLNHgANpnasagKYG-SPLHLT--KDY-RIAQSLISKGAEVNA 240
                 555...68*******************9944445444666.6****9..566.9******99***997 PP

  == domain 3  score: 37.6 bits;  conditional E-value: 8.1e-13
       Ank_2   1 LhlAakngnlelvklLl.egadpn.k..ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinlkd 83 
                 LhlAa  +nle+v+lLl +ga+pn +  +  ++Lh+   +    i++ L+++      ++  g tpL++A+  g+ +++  Ll  gad+n+++
  EEA22109.1 186 LHLAAIVDNLEIVDLLLnHGANPNaSagKYGSPLHLTKDY---RIAQSLISKgaevnaLNGAGSTPLFMAIATGRRNLAYRLLAAGADVNVQN 275
                 8*****9889*******999**998357445****98776...8******977674444466*********99**********99*****986 PP

  == domain 4  score: 32.9 bits;  conditional E-value: 2.4e-11
       Ank_2   1 LhlAakngnlelvklLl.egadpn.kngktaLhyAakngnleivklLleh...............adndgrtpLhyAarsghleivklLlekgadin 80 
                 L lA+k gn+e++  L  +g+d+  +  +  Lh+A+ n ++e+ ++Ll h               +++  +tpL++A+    +e++++L+  gad +
  EEA22109.1 282 LALACKAGNPEFIYELAsAGCDLQgSPSNPSLHIAVLNEHKEATQILLMHgretpaslncfllpaLTSMRETPLQLAVIRRDYEMFDVLVAAGADWK 378
                 679*****9*******99****987444799*****************9887788775555555444889**********999*******9999976 PP

  == domain 5  score: 29.6 bits;  conditional E-value: 2.7e-10
       Ank_2   3 lAakngnlelvklLlegadpn.k..ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlekgadinlkd 83 
                  Aa +g++ +v+lLl +++++ +  ++ ++L   +++g++ i++lL+e+       ad++g tp+ +A+ +g+  +v  Ll  ga+++ +d
  EEA22109.1 390 SAATEGKYTTVRLLLTHCNIKiSerDDTNPLPDVIEEGHKGIARLLIENdpalvnqADKKGITPIGAAIHYGS-SLVAELLAAGANLTDRD 479
                 577788789******888888735799********************9778886677799*********99*9.55555665899999876 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.11   3.2e+02      12      30 ..     125     143 ..     119     147 .. 0.87
   2 !   18.3   0.1   8.5e-07    0.0025       3      40 ..     184     220 ..     184     221 .. 0.84
   3 !   20.7   0.0   1.5e-07   0.00046      14      51 ..     225     261 ..     223     265 .. 0.88
   4 !   14.5   0.0   1.3e-05     0.039      19      51 ..     263     294 ..     258     298 .. 0.91
   5 !    8.1   0.0    0.0013         4      36      55 .]     310     329 ..     294     329 .. 0.86
   6 !    9.3   0.0   0.00057       1.7       3      55 .]     353     404 ..     351     404 .. 0.90
   7 !   11.4   0.0   0.00013      0.38       5      52 ..     420     467 ..     417     475 .. 0.80

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.11
       Ank_4  12 grlelvrlLlekgadinaq 30 
                 +r++l++l +e ga +n  
  EEA22109.1 125 ERIDLCQLFIEAGARVNSL 143
                 689*************987 PP

  == domain 2  score: 18.3 bits;  conditional E-value: 8.5e-07
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalh 40 
                 ++Lh aai  +le+v+lLl++ga++na+  +   ++lh
  EEA22109.1 184 EPLHLAAIVDNLEIVDLLLNHGANPNAS-AGKYGSPLH 220
                 58*************************9.444445665 PP

  == domain 3  score: 20.7 bits;  conditional E-value: 1.5e-07
       Ank_4  14 lelvrlLlekgadinaqdnrsGetalhiAakrgnveil 51 
                 ++++++L++kga++na  n+ G t+l +A+ +g+ + +
  EEA22109.1 225 YRIAQSLISKGAEVNAL-NGAGSTPLFMAIATGRRNLA 261
                 6789************9.**************987655 PP

  == domain 4  score: 14.5 bits;  conditional E-value: 1.3e-05
       Ank_4  19 lLlekgadinaqdnrsGetalhiAakrgnveil 51 
                 +Ll+ gad+n q n++ ++ l  A+k gn+e++
  EEA22109.1 263 RLLAAGADVNVQ-NKDKLSVLALACKAGNPEFI 294
                 5899********.****************9976 PP

  == domain 5  score: 8.1 bits;  conditional E-value: 0.0013
       Ank_4  36 etalhiAakrgnveilklLl 55 
                 ++ lhiA++++++e+++ Ll
  EEA22109.1 310 NPSLHIAVLNEHKEATQILL 329
                 789*************9997 PP

  == domain 6  score: 9.3 bits;  conditional E-value: 0.00057
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 t+L  a+i  ++e+ + L++ gad+    +++    ++ Aa  g++  ++lLl
  EEA22109.1 353 TPLQLAVIRRDYEMFDVLVAAGADWKSP-DIDWGGFIYSAATEGKYTTVRLLL 404
                 88999999****************9887.998888999999999***999997 PP

  == domain 7  score: 11.4 bits;  conditional E-value: 0.00013
       Ank_4   5 LhyaaisgrlelvrlLlekgad.inaqdnrsGetalhiAakrgnveilk 52 
                 L   +++g+  ++rlL+e+++  +n  +++ G t++  A+  g+  +++
  EEA22109.1 420 LPDVIEEGHKGIARLLIENDPAlVNQ-ADKKGITPIGAAIHYGSSLVAE 467
                 5566889************7553666.5************988765555 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0         4   1.2e+04      21      36 ..      18      34 ..      18      41 .. 0.68
   2 !   20.3   0.1   1.7e-07   0.00052      17      54 ..     183     220 ..     178     221 .. 0.91
   3 !   26.7   0.2   1.7e-09     5e-06       1      56 []     231     285 ..     231     285 .. 0.95
   4 !   16.3   0.1   3.1e-06    0.0092       1      35 [.     264     297 ..     264     307 .. 0.86
   5 ?    1.9   0.1     0.098   2.9e+02      19      41 ..     312     334 ..     297     338 .. 0.86
   6 !    8.8   0.0    0.0007       2.1      17      46 ..     352     381 ..     339     383 .. 0.88
   7 ?   -1.9   0.0       1.6   4.8e+03      23      48 ..     391     415 ..     388     420 .. 0.71
   8 !   13.5   0.0   2.2e-05     0.067       1      48 [.     435     479 ..     435     482 .. 0.89

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 4
       Ank_5 21 hvAak.ygaadvvrlLl 36
                h A++ +  ad vr++l
  EEA22109.1 18 HKAIEyRSTADSVRRYL 34
                78888555577777777 PP

  == domain 2  score: 20.3 bits;  conditional E-value: 1.7e-07
       Ank_5  17 ntpLhvAakygaadvvrlLlargadlnltdsrGltald 54 
                 ++pLh+Aa   ++++v lLl++ga++n+  + + ++l+
  EEA22109.1 183 FEPLHLAAIVDNLEIVDLLLNHGANPNASAGKYGSPLH 220
                 48**************************9999988887 PP

  == domain 3  score: 26.7 bits;  conditional E-value: 1.7e-09
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 L+++g a vn+l+g g tpL +A+  g+ +++ +Lla gad n+++++ l++l lA
  EEA22109.1 231 LISKG-AEVNALNGAGSTPLFMAIATGRRNLAYRLLAAGADVNVQNKDKLSVLALA 285
                 78889.*****************************************999988777 PP

  == domain 4  score: 16.3 bits;  conditional E-value: 3.1e-06
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlL 35 
                 Ll++g advn +++++ ++L +A+k+g+++ + +L
  EEA22109.1 264 LLAAG-ADVNVQNKDKLSVLALACKAGNPEFIYEL 297
                 8999*.**********************9987555 PP

  == domain 5  score: 1.9 bits;  conditional E-value: 0.098
       Ank_5  19 pLhvAakygaadvvrlLlargad 41 
                  Lh+A+ + + +  ++Ll++g  
  EEA22109.1 312 SLHIAVLNEHKEATQILLMHGRE 334
                 69****************99865 PP

  == domain 6  score: 8.8 bits;  conditional E-value: 0.0007
       Ank_5  17 ntpLhvAakygaadvvrlLlargadlnltd 46 
                 +tpL +A+ ++  +++ +L+a gad++  d
  EEA22109.1 352 ETPLQLAVIRRDYEMFDVLVAAGADWKSPD 381
                 4*************************9776 PP

  == domain 7  score: -1.9 bits;  conditional E-value: 1.6
       Ank_5  23 AakygaadvvrlLlargadlnltdsr 48 
                 Aa  g  + vrlLl  ++++++ + +
  EEA22109.1 391 AATEGKYTTVRLLL-THCNIKISERD 415
                 78888899999999.66666666655 PP

  == domain 8  score: 13.5 bits;  conditional E-value: 2.2e-05
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsr 48 
                 L+e++pa vn  d++g tp+  A++yg++ v++lL    a +nltd +
  EEA22109.1 435 LIENDPALVNQADKKGITPIGAAIHYGSSLVAELLA---AGANLTDRD 479
                 89**************************99999998...777776654 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       3.2   9.6e+03       3      12 ..      80      89 ..      72     103 .. 0.66
   2 ?    5.4   0.0     0.012        36       2      30 ..     114     141 ..     113     142 .. 0.90
   3 !   20.2   0.4   1.8e-07   0.00054       5      31 .]     185     210 ..     183     210 .. 0.96
   4 ?   -0.3   0.0      0.83   2.5e+03      15      31 .]     225     240 ..     216     240 .. 0.80
   5 !   10.9   0.0   0.00019      0.58       2      31 .]     245     273 ..     244     273 .. 0.95
   6 !    6.2   0.0    0.0065        19       3      29 ..     279     304 ..     277     306 .. 0.83
   7 ?    5.1   0.0     0.015        46       4      26 ..     311     332 ..     309     336 .. 0.86
   8 !    9.4   0.0   0.00058       1.7       3      28 ..     352     376 ..     350     378 .. 0.93
   9 ?    3.8   0.0      0.04   1.2e+02       9      29 ..     391     411 ..     388     413 .. 0.87
  10 ?    0.0   0.0      0.66     2e+03      12      30 ..     426     444 ..     423     445 .. 0.75
  11 ?    3.0   0.0     0.072   2.2e+02       2      29 ..     450     475 ..     449     476 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 3.2
       Ank_3  3 etpLhlAars 12
                +++Lh+++  
  EEA22109.1 80 YSILHQVIDD 89
                4666666654 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.012
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G  +L +A+ + +++++++++e  ga vn
  EEA22109.1 114 GILLLNEAMVCERIDLCQLFIE-AGARVN 141
                 667999****************.899888 PP

  == domain 3  score: 20.2 bits;  conditional E-value: 1.8e-07
       Ank_3   5 pLhlAarsgnleivkfLlenkgadvna 31 
                 pLhlAa  +nleiv++Ll+ +ga++na
  EEA22109.1 185 PLHLAAIVDNLEIVDLLLN-HGANPNA 210
                 9******************.9****96 PP

  == domain 4  score: -0.3 bits;  conditional E-value: 0.83
       Ank_3  15 leivkfLlenkgadvna 31 
                 + i++ L+  kga+vna
  EEA22109.1 225 YRIAQSLIS-KGAEVNA 240
                 567899999.9**9996 PP

  == domain 5  score: 10.9 bits;  conditional E-value: 0.00019
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvna 31 
                 G tpL++A+  g+ +++  Ll   gadvn+
  EEA22109.1 245 GSTPLFMAIATGRRNLAYRLLA-AGADVNV 273
                 89********************.9****95 PP

  == domain 6  score: 6.2 bits;  conditional E-value: 0.0065
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadv 29 
                  + L lA+++gn+e +  L    g+d+
  EEA22109.1 279 LSVLALACKAGNPEFIYELAS-AGCDL 304
                 57899*********7777777.89987 PP

  == domain 7  score: 5.1 bits;  conditional E-value: 0.015
       Ank_3   4 tpLhlAarsgnleivkfLlenkg 26 
                   Lh+A+++ + e  + Ll  +g
  EEA22109.1 311 PSLHIAVLNEHKEATQILLM-HG 332
                 57***********9999998.55 PP

  == domain 8  score: 9.4 bits;  conditional E-value: 0.00058
       Ank_3   3 etpLhlAarsgnleivkfLlenkgad 28 
                 etpL lA+   ++e+ + L+   gad
  EEA22109.1 352 ETPLQLAVIRRDYEMFDVLVA-AGAD 376
                 8********************.8998 PP

  == domain 9  score: 3.8 bits;  conditional E-value: 0.04
       Ank_3   9 AarsgnleivkfLlenkgadv 29 
                 Aa  g+++ v++Ll ++++ +
  EEA22109.1 391 AATEGKYTTVRLLLTHCNIKI 411
                 89999**99******999987 PP

  == domain 10  score: 0.0 bits;  conditional E-value: 0.66
       Ank_3  12 sgnleivkfLlenkgadvn 30 
                  g+  i+++L+en  a vn
  EEA22109.1 426 EGHKGIARLLIENDPALVN 444
                 5777799*****8777666 PP

  == domain 11  score: 3.0 bits;  conditional E-value: 0.072
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadv 29 
                 G tp+  A+++g+   v  Ll   ga++
  EEA22109.1 450 GITPIGAAIHYGSSL-VAELLA-AGANL 475
                 89************8.777777.58775 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0      0.59   1.8e+03      11      29 ..     126     142 ..     117     143 .. 0.80
   2 !   23.8   0.9   1.4e-08   4.3e-05       5      29 ..     185     210 ..     184     211 .. 0.96
   3 !    9.1   0.0   0.00062       1.9       4      31 ..     217     242 ..     217     242 .. 0.84
   4 !    9.0   0.0   0.00069         2       2      32 .]     245     276 ..     244     276 .. 0.85
   5 ?   -0.2   0.0      0.53   1.6e+03       4      27 ..     280     304 ..     277     308 .. 0.77
   6 !    9.1   0.1   0.00062       1.8       6      28 ..     313     340 ..     312     341 .. 0.87
   7 ?    3.0   0.0     0.055   1.6e+02       4      26 ..     353     376 ..     350     416 .. 0.50
   8 ?    0.6   0.0      0.31   9.2e+02      12      29 ..     426     445 ..     423     448 .. 0.67
   9 !    8.2   0.1    0.0012       3.6       2      31 ..     450     479 ..     449     480 .. 0.87

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.59
                 HHTTHHHHHHHH.TTTSTTC CS
         Ank  11 tngkkriiklLL.hGAnlna 29 
                 +++    ++l++  GA +n+
  EEA22109.1 126 RID---LCQLFIeAGARVNS 142
                 566...99****88998886 PP

  == domain 2  score: 23.8 bits;  conditional E-value: 1.4e-08
                 HHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   5 PLHlAatngkkriiklLL.hGAnlna 29 
                 PLHlAa  ++++i+ lLL hGAn+na
  EEA22109.1 185 PLHLAAIVDNLEIVDLLLnHGANPNA 210
                 9*****99*****************8 PP

  == domain 3  score: 9.1 bits;  conditional E-value: 0.00062
                 BHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnlnald 31 
                 +PLHl    ++ ri++ L+ +GA++nal+
  EEA22109.1 217 SPLHL-T--KDYRIAQSLIsKGAEVNALN 242
                 69999.6..5556******88******97 PP

  == domain 4  score: 9.0 bits;  conditional E-value: 0.00069
                 SBBHHHHHH...HHTTHHHHHHHH.TTTSTTCBTT CS
         Ank   2 GnTPLHlAa...tngkkriiklLL.hGAnlnaldn 32 
                 G TPL +A+   +++    +  LL  GA++n +++
  EEA22109.1 245 GSTPLFMAIatgRRN---LAYRLLaAGADVNVQNK 276
                 88******9666555...**99**88******995 PP

  == domain 5  score: -0.2 bits;  conditional E-value: 0.53
                 BHHHHHHHHTTHHHHHHHH.TTTST CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnl 27 
                 ++L lA+  g+++ i +L   G++l
  EEA22109.1 280 SVLALACKAGNPEFIYELAsAGCDL 304
                 57889**99**99998876446655 PP

  == domain 6  score: 9.1 bits;  conditional E-value: 0.00062
                 HHHHHHHTTHHHHHHHH.TT....TSTT CS
         Ank   6 LHlAatngkkriiklLL.hG....Anln 28 
                 LH+A+ n +k+ ++ LL hG    A+ln
  EEA22109.1 313 LHIAVLNEHKEATQILLmHGretpASLN 340
                 9******************977666666 PP

  == domain 7  score: 3.0 bits;  conditional E-value: 0.055
                 BHHHHHHHHTTHHHHHHHH.TTTS CS
         Ank   4 TPLHlAatngkkriiklLL.hGAn 26 
                 TPL lA+ + + ++   L+  GA+
  EEA22109.1 353 TPLQLAVIRRDYEMFDVLVaAGAD 376
                 888886422223344444433433 PP

  == domain 8  score: 0.6 bits;  conditional E-value: 0.31
                 HTTHHHHHHHH.TT.TSTTC CS
         Ank  12 ngkkriiklLL.hG.Anlna 29 
                 +g+k i++lL+ +  A +n+
  EEA22109.1 426 EGHKGIARLLIeNDpALVNQ 445
                 57788******533355565 PP

  == domain 9  score: 8.2 bits;  conditional E-value: 0.0012
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlnald 31 
                 G TP   A+++g+  +++ LL  GAnl+ +d
  EEA22109.1 450 GITPIGAAIHYGSSLVAE-LLaAGANLTDRD 479
                 89999999*999999999.7769****9887 PP

>> PRANC  PRANC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.1   1.1e-05     0.033      56      96 ..      18      58 ..       1      59 [. 0.70
   2 ?   -2.2   0.0       1.9   5.6e+03      53      77 ..      72      96 ..      64     101 .. 0.52

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 1.1e-05
       PRANC 56 ekaievlnnicsk..kslWnlLPiEIkykIleyLndkdLknll 96
                +kaie+ +    +  + ++++LPiE+  +I++yL+  d+ +l+
  EEA22109.1 18 HKAIEYRSTA--DsvRRYLYRLPIELFTMIMDYLSLRDILYLC 58
                3444444444..23699*********************98876 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 1.9
       PRANC 53 kliekaie.vlnnicskkslWnlLPi 77
                 li +a++ ++   +  ++ W+++P+
  EEA22109.1 72 HLIAEASSySILHQVI-DDDWSIIPM 96
                3343333303333322.468998885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (535 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       484  (0.0269954); expected 358.6 (0.02)
Passed bias filter:                      462  (0.0257683); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.42
# Mc/sec: 3796.13
//
Query:       EEA22110.1  [L=588]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-31  108.2   6.7    5.5e-07   30.1   0.2    6.4  7  Ank_2     Ankyrin repeats (3 copies)
    1.6e-22   79.2   9.8    0.00097   19.4   0.1    7.0  7  Ank_5     Ankyrin repeats (many copies)
    3.9e-22   77.7  19.6    1.5e-05   25.2   0.1   10.0 11  Ank       Ankyrin repeat
    4.4e-21   75.0  13.9    9.6e-05   22.9   0.0    8.8 10  Ank_4     Ankyrin repeats (many copies)
    2.1e-20   70.6  14.7     0.0005   20.3   0.0   12.1 13  Ank_3     Ankyrin repeat


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0     0.031   1.1e+02      55      80 ..      27      52 ..      15      55 .. 0.88
   2 !   18.5   0.0   6.2e-07    0.0022       7      81 ..      35     125 ..      29     127 .. 0.65
   3 !   30.1   0.2   1.5e-10   5.5e-07       8      78 ..     141     218 ..     129     221 .. 0.83
   4 !   24.6   0.0   7.6e-09   2.7e-05      16      79 ..     226     295 ..     223     298 .. 0.83
   5 ?    2.9   0.0     0.045   1.6e+02       4      74 ..     309     371 ..     302     415 .. 0.49
   6 ?   -3.2   0.0       3.8   1.4e+04      51      65 ..     448     461 ..     417     471 .. 0.58
   7 !   27.9   0.0   7.6e-10   2.7e-06       9      73 ..     497     571 ..     492     581 .. 0.83

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.031
       Ank_2 55 tpLhyAarsghleivklLlekgadin 80
                 pL  A ++ h+++++l+le ga +n
  EEA22110.1 27 RPLLSALEKPHYDFCDLFLEAGARVN 52
                69999**9999********99*9998 PP

  == domain 2  score: 18.5 bits;  conditional E-value: 6.2e-07
       Ank_2   7 ngnlelvklLl.egadpn...k...ngktaLhyAakngnlei..vklLleh.....ad..ndgrtpLhyAarsghleivklLlekgadinl 81 
                 + ++++++l+l +ga++n   +    + t  h+  +  ++ i   + L +      ++  ++   pLh+A+ +g+ e+v+l+l +gad+nl
  EEA22110.1  35 KPHYDFCDLFLeAGARVNfceTtsiSEDTMRHFMSSIEDTTInrFRDLADSrrrgsMRlaSTPLAPLHIAVTKGNVELVELFLRHGADPNL 125
                 456677788887777777654145655566664444443333336777765544442244556679*****************99****97 PP

  == domain 3  score: 30.1 bits;  conditional E-value: 1.5e-10
       Ank_2   8 gnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh...ad...ndgrtpLhyAarsghleivklLlekgad 78 
                 g   + klL+ +gad+n  +  g ++L++A  +g++++  +L+e+   +d   ++  t L +A++     +v+lLl+ +++
  EEA22110.1 141 G---IAKLLVaNGADVNarNgLGASPLFIALDRGKKDLFTMLIEAganVDlvaDNDDTLLNLAIKRRAGTFVELLLDADCK 218
                 5...999**9*******864899********************97756446668899*******99888*******75444 PP

  == domain 4  score: 24.6 bits;  conditional E-value: 7.6e-09
       Ank_2  16 Ll.egadpn..kngktaLhyAakngnleivklLleh...ad...ndgrtpLhyAarsghleivklLlekgadi 79 
                 L+ +gad++   ng taLh+       ++++lLl++   +d   ++g tp ++Aa+s +l+++++L+  ga++
  EEA22110.1 226 LIhCGADISilYNGGTALHTTPCL---DTASLLLSYgadIDkedCEGSTPFMLAASSRNLRLMEVLILAGAEV 295
                 667999998644*******77665...88******89553366789*********************779887 PP

  == domain 5  score: 2.9 bits;  conditional E-value: 0.045
       Ank_2   4 AakngnlelvklLlegadp..........n.k........ngktaLhyAakngnleivklLlehadndgrtpLhyAarsghleivklLle 74 
                  ++ g+++++k +++ +d+          n           +k+ L                           ++A+ + ++ i++lL+e
  EEA22110.1 309 LVRAGAYHILKSIISRCDLrlafdegeygNgYgdedgdesGDKNLL---------------------------YLAIIHFQEGIANLLIE 371
                 3334444444444433332111111111101011222232334555...........................55555544445555543 PP

  == domain 6  score: -3.2 bits;  conditional E-value: 3.8
       Ank_2  51 ndgrtpLhyAarsgh 65 
                 ++   pL++A   g+
  EEA22110.1 448 QHVDLPLIVAT-AGR 461
                 33346777776.455 PP

  == domain 7  score: 27.9 bits;  conditional E-value: 7.6e-10
       Ank_2   9 nlelvklLl.egadpn.k..ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLl 73 
                 n+++++ Ll +gad++    +g+ +Lh+Aa ++++ ++++Ll+        d+ g+tp ++Aa+ +h ++ k+L 
  EEA22110.1 497 NYSILQTLLdYGADVSqAewEGMGILHVAAWRNDERLMEMLLATganplfKDSMGHTPAYWAAQMSHHKMEKMLR 571
                 457999*********96369*************99*******966456656699*********999999999886 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0       1.2   4.3e+03      15      40 ..      24      49 ..      19      56 .. 0.79
   2 !   19.4   0.1   2.7e-07   0.00097      19      47 ..     100     128 ..      87     136 .. 0.89
   3 !    8.4   0.1   0.00078       2.8      29      53 ..     140     164 ..     132     167 .. 0.81
   4 !   17.0   0.1   1.5e-06    0.0054       1      44 [.     179     219 ..     179     221 .. 0.93
   5 ?   -0.4   0.0      0.43   1.5e+03       1      22 [.     226     245 ..     226     245 .. 0.81
   6 !   16.2   0.0   2.8e-06      0.01       1      46 [.     255     302 ..     255     309 .. 0.91
   7 !   17.4   0.0   1.1e-06    0.0041       1      52 [.     504     554 ..     504     558 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 1.2
       Ank_5 15 ggntpLhvAakygaadvvrlLlarga 40
                + + pL  A ++ + d + l+l+ ga
  EEA22110.1 24 WTYRPLLSALEKPHYDFCDLFLEAGA 49
                5678999999999****999996555 PP

  == domain 2  score: 19.4 bits;  conditional E-value: 2.7e-07
       Ank_5  19 pLhvAakygaadvvrlLlargadlnltds 47 
                 pLh+A+ +g+ ++v+l+l +gad+nl  +
  EEA22110.1 100 PLHIAVTKGNVELVELFLRHGADPNLHAE 128
                 9************************9765 PP

  == domain 3  score: 8.4 bits;  conditional E-value: 0.00078
       Ank_5  29 advvrlLlargadlnltdsrGltal 53 
                   +++lL+a+gad n++++ G ++l
  EEA22110.1 140 IGIAKLLVANGADVNARNGLGASPL 164
                 56888899*********99999998 PP

  == domain 4  score: 17.0 bits;  conditional E-value: 1.5e-06
       Ank_5   1 Llehg.padvnrldgggntpLhvAakygaadvvrlLlargadlnl 44 
                 L+e+g ++d+ + + +  t L++A+k++a + v+lLl   ad+++
  EEA22110.1 179 LIEAGaNVDLVADNDD--TLLNLAIKRRAGTFVELLL--DADCKI 219
                 899**99999999999..*******************..888875 PP

  == domain 5  score: -0.4 bits;  conditional E-value: 0.43
       Ank_5   1 LlehgpadvnrldgggntpLhv 22 
                 L+++g ad+  l +gg t+Lh+
  EEA22110.1 226 LIHCG-ADISILYNGG-TALHT 245
                 78899.8888888888.***96 PP

  == domain 6  score: 16.2 bits;  conditional E-value: 2.8e-06
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl...argadlnltd 46 
                 Ll++g ad++ +d +g tp+++Aa+ ++++++++L+   a+ + ++l+d
  EEA22110.1 255 LLSYG-ADIDKEDCEGSTPFMLAASSRNLRLMEVLIlagAEVCPIFLRD 302
                 89999.******************************8888888888776 PP

  == domain 7  score: 17.4 bits;  conditional E-value: 1.1e-06
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGlta 52 
                 Ll++g adv   + +g+ +LhvAa+++  +++++Lla ga++  +ds+G t+
  EEA22110.1 504 LLDYG-ADVSQAEWEGMGILHVAAWRNDERLMEMLLATGANPLFKDSMGHTP 554
                 78888.888888889999*********************************9 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       1.7   6.2e+03       8      28 ..      31      52 ..      28      54 .. 0.70
   2 !   25.2   0.1   4.2e-09   1.5e-05       5      30 ..     100     126 ..      99     127 .. 0.97
   3 !   14.2   0.1   1.3e-05     0.046       4      31 ..     132     157 ..     132     157 .. 0.93
   4 !    9.3   0.0   0.00044       1.6       2      29 ..     160     188 ..     159     193 .. 0.89
   5 ?    0.6   0.1      0.25   8.9e+02      19      28 ..     224     234 ..     192     237 .. 0.67
   6 !    9.2   0.2   0.00049       1.8       2      31 ..     239     266 ..     238     267 .. 0.87
   7 !    8.8   0.0   0.00065       2.3       2      27 ..     269     295 ..     268     303 .. 0.88
   8 ?   -3.0   0.2       3.5   1.3e+04       6      22 ..     354     370 ..     353     373 .. 0.76
   9 ?    1.9   0.0       0.1   3.6e+02      16      28 ..     499     512 ..     482     515 .. 0.85
  10 !   12.1   0.0   5.9e-05      0.21       5      31 ..     521     548 ..     517     549 .. 0.87
  11 ?   -1.5   0.1       1.1     4e+03       1      14 [.     550     563 ..     550     573 .. 0.71

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.7
                HHHHHTTHHHHHHHH.TTTSTT CS
         Ank  8 lAatngkkriiklLL.hGAnln 28
                 A    + + + l+L  GA +n
  EEA22110.1 31 SALEKPHYDFCDLFLeAGARVN 52
                555455667999***8899776 PP

  == domain 2  score: 25.2 bits;  conditional E-value: 4.2e-09
                 HHHHHHHHTTHHHHHHHH.TTTSTTCB CS
         Ank   5 PLHlAatngkkriiklLL.hGAnlnal 30 
                 PLH+A+t g+++ ++l+L hGA++n++
  EEA22110.1 100 PLHIAVTKGNVELVELFLrHGADPNLH 126
                 9************************87 PP

  == domain 3  score: 14.2 bits;  conditional E-value: 1.3e-05
                 BHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnlnald 31 
                 T+LH    +g   i+klL+ +GA++na++
  EEA22110.1 132 TALHFTKDIG---IAKLLVaNGADVNARN 157
                 999*97799*...******99******97 PP

  == domain 4  score: 9.3 bits;  conditional E-value: 0.00044
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlna 29 
                 G +PL +A  +gkk+   +L+  GAn+++
  EEA22110.1 160 GASPLFIALDRGKKDLFTMLIeAGANVDL 188
                 678****999***********88***986 PP

  == domain 5  score: 0.6 bits;  conditional E-value: 0.25
                 HHHH.TTTSTT CS
         Ank  19 klLL.hGAnln 28 
                 ++L+ +GA++ 
  EEA22110.1 224 SMLIhCGADIS 234
                 45775588876 PP

  == domain 6  score: 9.2 bits;  conditional E-value: 0.00049
                 SBBHHH.HHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   2 GnTPLH.lAatngkkriiklLL.hGAnlnald 31 
                 G T+LH  ++  +    ++lLL +GA+++  d
  EEA22110.1 239 GGTALHtTPC-LD---TASLLLsYGADIDKED 266
                 669***8899.79...******88****9887 PP

  == domain 7  score: 8.8 bits;  conditional E-value: 0.00065
                 SBBHHHHHHHHTTHHHHHHHH.TTTST CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnl 27 
                 G TP +lAa+  ++r  + L+  GA++
  EEA22110.1 269 GSTPFMLAASSRNLRLMEVLIlAGAEV 295
                 89*******9999*****999999976 PP

  == domain 8  score: -3.0 bits;  conditional E-value: 3.5
                 HHHHH...HHTTHHHHHHHH CS
         Ank   6 LHlAa...tngkkriiklLL 22 
                 L lA+   ++g   i+ lL+
  EEA22110.1 354 LYLAIihfQEG---IANLLI 370
                 77888888778...888887 PP

  == domain 9  score: 1.9 bits;  conditional E-value: 0.1
                 HHHHHHH.TTTSTT CS
         Ank  16 riiklLL.hGAnln 28 
                 +i++ LL +GA++ 
  EEA22110.1 499 SILQTLLdYGADVS 512
                 599****78***95 PP

  == domain 10  score: 12.1 bits;  conditional E-value: 5.9e-05
                 HHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   5 PLHlAatngkkriiklLL.hGAnlnald 31 
                  LH+Aa+++++r  ++LL  GAn+  +d
  EEA22110.1 521 ILHVAAWRNDERLMEMLLaTGANPLFKD 548
                 59****************99***97666 PP

  == domain 11  score: -1.5 bits;  conditional E-value: 1.1
                 TSBBHHHHHHHHTT CS
         Ank   1 dGnTPLHlAatngk 14 
                 +G+TP  +Aa+  +
  EEA22110.1 550 MGHTPAYWAAQMSH 563
                 69***999995544 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0     0.026        94       2      28 ..      26      52 ..      25      67 .. 0.85
   2 !   13.9   0.1   1.7e-05     0.061       4      40 ..     100     135 ..      98     136 .. 0.74
   3 !   22.9   0.0   2.7e-08   9.6e-05      16      55 .]     142     180 ..     138     180 .. 0.94
   4 !    9.1   0.0   0.00056         2      15      55 .]     174     213 ..     171     213 .. 0.86
   5 ?   -0.6   0.0      0.59   2.1e+03      23      40 ..     228     244 ..     224     245 .. 0.80
   6 !   15.3   0.0   6.5e-06     0.023      13      55 .]     248     289 ..     241     289 .. 0.90
   7 ?   -1.8   0.1       1.4   5.1e+03       4      22 ..     305     323 ..     304     333 .. 0.79
   8 ?   -1.5   0.0       1.2   4.2e+03       5      23 ..     354     372 ..     352     385 .. 0.78
   9 !   12.0   0.0   6.6e-05      0.24      13      55 .]     497     538 ..     494     538 .. 0.90
  10 !   12.9   0.1   3.7e-05      0.13       2      54 ..     519     570 ..     518     572 .. 0.89

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.026
       Ank_4  2 ltaLhyaaisgrlelvrlLlekgadin 28
                +++L +a ++ +++ ++l le ga +n
  EEA22110.1 26 YRPLLSALEKPHYDFCDLFLEAGARVN 52
                67899*****************98876 PP

  == domain 2  score: 13.9 bits;  conditional E-value: 1.7e-05
       Ank_4   4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalh 40 
                 +Lh a+ +g++elv+l l +gad+n    +   talh
  EEA22110.1 100 PLHIAVTKGNVELVELFLRHGADPNLH-AELFGTALH 135
                 799999999999999999999998865.333556666 PP

  == domain 3  score: 22.9 bits;  conditional E-value: 2.7e-08
       Ank_4  16 lvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +++lL+++gad+na+ n+ G ++l iA+ rg+++ + +L+
  EEA22110.1 142 IAKLLVANGADVNAR-NGLGASPLFIALDRGKKDLFTMLI 180
                 789************.**********************98 PP

  == domain 4  score: 9.1 bits;  conditional E-value: 0.00056
       Ank_4  15 elvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +l   L+e ga+++ +  ++++t+l  A+kr    +++lLl
  EEA22110.1 174 DLFTMLIEAGANVDLV-ADNDDTLLNLAIKRRAGTFVELLL 213
                 66678***********.566***********9999999887 PP

  == domain 5  score: -0.6 bits;  conditional E-value: 0.59
       Ank_4  23 k.gadinaqdnrsGetalh 40 
                 + gadi      +G talh
  EEA22110.1 228 HcGADISIL--YNGGTALH 244
                 558888888..99*****9 PP

  == domain 6  score: 15.3 bits;  conditional E-value: 6.5e-06
       Ank_4  13 rlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +l+++ lLl++gadi++  + +G t++  Aa+  n++  + L+
  EEA22110.1 248 CLDTASLLLSYGADIDKE-DCEGSTPFMLAASSRNLRLMEVLI 289
                 89***************5.777*************99999987 PP

  == domain 7  score: -1.8 bits;  conditional E-value: 1.4
       Ank_4   4 aLhyaaisgrlelvrlLle 22 
                 +Lh+++ +g + +++++++
  EEA22110.1 305 ILHSLVRAGAYHILKSIIS 323
                 6899999999999998885 PP

  == domain 8  score: -1.5 bits;  conditional E-value: 1.2
       Ank_4   5 LhyaaisgrlelvrlLlek 23 
                 L  a+i++++ ++ lL+e 
  EEA22110.1 354 LYLAIIHFQEGIANLLIEA 372
                 455777*******999985 PP

  == domain 9  score: 12.0 bits;  conditional E-value: 6.6e-05
       Ank_4  13 rlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++ +++ Ll++gad+      +G+  lh Aa+r++ +  ++Ll
  EEA22110.1 497 NYSILQTLLDYGADVSQA-EWEGMGILHVAAWRNDERLMEMLL 538
                 77899*********9997.666******************997 PP

  == domain 10  score: 12.9 bits;  conditional E-value: 3.7e-05
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54 
                 +++Lh aa  ++++l + Ll++ga++    ++ G t+ + Aa++++ ++ k+L
  EEA22110.1 519 MGILHVAAWRNDERLMEMLLATGANPLFK-DSMGHTPAYWAAQMSHHKMEKML 570
                 889**********************8776.999************97775555 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0     0.023        83       4      30 ..      27      52 ..      25      53 .. 0.91
   2 !   20.3   0.0   1.4e-07    0.0005       5      30 ..     100     124 ..      98     125 .. 0.96
   3 ?    4.3   0.0     0.023        81       9      31 .]     133     155 ..     129     155 .. 0.77
   4 !   10.5   0.0   0.00022       0.8       2      30 ..     160     187 ..     159     188 .. 0.94
   5 ?    3.2   0.0     0.051   1.8e+02       3      27 ..     194     217 ..     192     221 .. 0.85
   6 ?   -1.7   0.0         2   7.2e+03      20      30 ..     225     234 ..     223     235 .. 0.82
   7 ?    1.5   0.0      0.19   6.8e+02      16      30 ..     250     263 ..     238     264 .. 0.72
   8 !   12.0   0.0   7.1e-05      0.26       1      28 [.     268     294 ..     268     296 .. 0.90
   9 ?    1.5   0.1      0.18   6.6e+02       5      26 ..     305     324 ..     303     329 .. 0.85
  10 ?   -3.0   0.0         5   1.8e+04       8      23 ..     390     405 ..     386     409 .. 0.64
  11 ?    3.5   0.0      0.04   1.4e+02      13      30 ..     496     512 ..     494     513 .. 0.88
  12 ?    3.8   0.0     0.033   1.2e+02       2      29 ..     518     544 ..     517     546 .. 0.86
  13 ?    1.3   0.0      0.22     8e+02       2      21 ..     551     570 ..     550     574 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.023
       Ank_3  4 tpLhlAarsgnleivkfLlenkgadvn 30
                 pL  A++  +++ ++++le  ga vn
  EEA22110.1 27 RPLLSALEKPHYDFCDLFLE-AGARVN 52
                59999***************.899888 PP

  == domain 2  score: 20.3 bits;  conditional E-value: 1.4e-07
       Ank_3   5 pLhlAarsgnleivkfLlenkgadvn 30 
                 pLh+A+  gn+e+v+++l+ +gad+n
  EEA22110.1 100 PLHIAVTKGNVELVELFLR-HGADPN 124
                 9******************.9****9 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.023
       Ank_3   9 Aarsgnle.ivkfLlenkgadvna 31 
                 A+++++   i+k+L+  +gadvna
  EEA22110.1 133 ALHFTKDIgIAKLLVA-NGADVNA 155
                 55556665689*****.8****96 PP

  == domain 4  score: 10.5 bits;  conditional E-value: 0.00022
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G +pL++A+  g+ ++  +L+e  ga+v+
  EEA22110.1 160 GASPLFIALDRGKKDLFTMLIE-AGANVD 187
                 88********************.8**997 PP

  == domain 5  score: 3.2 bits;  conditional E-value: 0.051
       Ank_3   3 etpLhlAarsgnleivkfLlenkga 27 
                  t+L lA++    + v++Ll+   +
  EEA22110.1 194 DTLLNLAIKRRAGTFVELLLD-ADC 217
                 69******************9.454 PP

  == domain 6  score: -1.7 bits;  conditional E-value: 2
       Ank_3  20 fLlenkgadvn 30 
                 +L+  +gad+ 
  EEA22110.1 225 MLIH-CGADIS 234
                 7888.****97 PP

  == domain 7  score: 1.5 bits;  conditional E-value: 0.19
       Ank_3  16 eivkfLlenkgadvn 30 
                 + + +Ll  +gad++
  EEA22110.1 250 DTASLLLS-YGADID 263
                 45889999.9***97 PP

  == domain 8  score: 12.0 bits;  conditional E-value: 7.1e-05
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgad 28 
                 +G tp++lAa+s nl +++ L+   ga+
  EEA22110.1 268 EGSTPFMLAASSRNLRLMEVLIL-AGAE 294
                 599*******************9.7876 PP

  == domain 9  score: 1.5 bits;  conditional E-value: 0.18
       Ank_3   5 pLhlAarsgnleivkfLlenkg 26 
                 +Lh  +r+g + i+k ++    
  EEA22110.1 305 ILHSLVRAGAYHILKSIIS--R 324
                 69************99998..4 PP

  == domain 10  score: -3.0 bits;  conditional E-value: 5
       Ank_3   8 lAarsgnleivkfLle 23 
                  Aa+  + +++k +++
  EEA22110.1 390 AAALRSSSTLLKKIID 405
                 5666666667777776 PP

  == domain 11  score: 3.5 bits;  conditional E-value: 0.04
       Ank_3  13 gnleivkfLlenkgadvn 30 
                 +n++i++ Ll+ +gadv 
  EEA22110.1 496 TNYSILQTLLD-YGADVS 512
                 58899******.****96 PP

  == domain 12  score: 3.8 bits;  conditional E-value: 0.033
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadv 29 
                 G+ +Lh+Aa  ++  ++++Ll   ga++
  EEA22110.1 518 GMGILHVAAWRNDERLMEMLLA-TGANP 544
                 677899999999999*******.79987 PP

  == domain 13  score: 1.3 bits;  conditional E-value: 0.22
       Ank_3   2 GetpLhlAarsgnleivkfL 21 
                 G tp ++Aa   ++++ k+L
  EEA22110.1 551 GHTPAYWAAQMSHHKMEKML 570
                 89***********9965554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (588 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       341  (0.0190195); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.59u 0.30s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 3878.26
//
Query:       EEA22111.1  [L=226]
Description: hypothetical protein PMAA_058910 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
       0.19   11.9   0.4         15    5.8   0.0    2.2  2  DOPA_dioxygen  Dopa 4,5-dioxygenase family


Domain annotation for each model (and alignments):
>> DOPA_dioxygen  Dopa 4,5-dioxygenase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0   0.00082        15      17      75 ..      35      94 ..      31     115 .. 0.81
   2 ?    4.3   0.1    0.0025        45      82     105 ..     199     222 ..     175     224 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.00082
                   HHHHHHHHHH.HHTTTT..E---BSS--TT-SSEEEEEEE.-HHHHHHHHHHHHHH-TT- CS
  DOPA_dioxygen 17 eAkeLrekir.refeeelrvgklaekpiGPhpvamfevdvftpeqfgkvvswlalnrgpl 75
                   +A +L +k++  +++++++v++++++ i       +e++ f+++ f  + +wl   rg++
     EEA22111.1 35 FAWRLPKKLIsMRVPKAIQVEHVTSEEIVNSGALRWEIEHFSQDAFRLFAEWLYNVRGQI 94
                   56666665441456777888888888888888999*******************999986 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.0025
                    ESS-HHHHHHHS-EEESS-----G CS
  DOPA_dioxygen  82 ntgdelrdHteraiWlGeklpldl 105
                    + g+e +d  e  +W+G++ +l +
     EEA22111.1 199 QGGSEHQDFDEILTWMGQNCQLWI 222
                    5678999************99865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (226 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       350  (0.0195214); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.41
# Mc/sec: 1665.95
//
Query:       EEA22112.1  [L=291]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
     0.0024   17.7   0.0     0.0037   17.1   0.0    1.2  1  Methyltransf_31  Methyltransferase domain
  ------ inclusion threshold ------
       0.13   13.0   0.0       0.21   12.3   0.0    1.3  1  Methyltransf_25  Methyltransferase domain


Domain annotation for each model (and alignments):
>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   0.0   4.1e-07    0.0037      15      90 ..      93     175 ..      79     207 .. 0.74

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 4.1e-07
  Methyltransf_31  15 Geltfelae.elgpkaevvGiDiseeaielAre.naqklgld....nveFeqgdieelekl.ledekfDlilsnevlnaladp 90 
                      G ++ e++e +  +++++v++D+s ea++l re +++k + d     ++   +++ + ++  l  ++fD++l++++ +a+a++
       EEA22112.1  93 GSKLCEAFErRGWKGCDIVNVDFSSEAVRLGRErETEKSNPDsimhWIQADLCSWKDVSQRlLPLAPFDVLLDKSTSDAIAAS 175
                      44445555544455889****************66777777774445566667777877676777*********999666654 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   2.4e-05      0.21      11      67 ..      96     162 ..      83     183 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 2.4e-05
                      HHHHHHCTS.TSSEEEEEESSHHHHHHHHHHHHH.TTT..TEEEEESBCCGBS......SSTTTEEE CS
  Methyltransf_25  11 ltlalakrl.gkakvtgvDiseemleaareraee.egl..nvefvqgdaedlp......fedgsfDl 67 
                      l++a+ +r+ + ++++ vD+s+e+++  rer  e +++   ++++q+d+ +++      ++ + fD+
       EEA22112.1  96 LCEAFERRGwKGCDIVNVDFSSEAVRLGRERETEkSNPdsIMHWIQADLCSWKdvsqrlLPLAPFDV 162
                      3445555546369****************999884555888999****9887633333335555665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (291 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       253  (0.0141112); expected 358.6 (0.02)
Passed bias filter:                      242  (0.0134977); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.24s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 2135.55
//
Query:       EEA22113.1  [L=176]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00026   21.5   2.0    0.00045   20.8   2.0    1.4  1  DUF4690   Small Novel Rich in Cartilage
  ------ inclusion threshold ------
       0.11   12.5   0.1       0.15   12.0   0.1    1.2  1  PTP_tm    Transmembrane domain of protein tyrosine phosphatas


Domain annotation for each model (and alignments):
>> DUF4690  Small Novel Rich in Cartilage
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8   2.0     5e-08   0.00045      23      94 ..      39     110 ..      25     111 .. 0.75

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 5e-08
     DUF4690  23 ple..sttkeresdltdlpastselepeDtthlerldeeegslGPGaiaaiviaalLgasvllaLvvitLrkfs 94 
                 +++  st+ +++ ++t   + t ++  e t  + +      sl PGaia i i ++ ga ++ a +      f+
  EEA22113.1  39 STSslSTSATQAATATTSVPGTGTISNETTSPSPTYTP--NSLTPGAIAGITIGSIAGALIICAFIYYIFNNFT 110
                 33324677777777777667777887776666655555..5************************988777776 PP

>> PTP_tm  Transmembrane domain of protein tyrosine phosphatase, receptor type J
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.1   1.7e-05      0.15     153     179 ..      80     106 ..      49     110 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 1.7e-05
      PTP_tm 153 dPgviaGavlGcilgalvivavgGfif 179
                  Pg iaG  +G i gal+i a   +if
  EEA22113.1  80 TPGAIAGITIGSIAGALIICAFIYYIF 106
                 59*********************9999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (176 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       610  (0.0340231); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.41u 0.24s 00:00:00.64 Elapsed: 00:00:00.39
# Mc/sec: 1356.86
//
Query:       EEA22114.1  [L=352]
Description: transposable element tc1 transposase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      7e-13   48.6   0.1      2e-12   47.1   0.1    1.8  1  DDE_3           DDE superfamily endonuclease
      7e-10   39.0   0.5    1.6e-09   37.9   0.5    1.6  1  HTH_Tnp_Tc3_2   Transposase
     0.0082   16.1   0.0      0.021   14.8   0.0    1.7  1  HTH_12          Ribonuclease R winged-helix domain
  ------ inclusion threshold ------
       0.12   13.0   0.6       0.12   13.0   0.6    3.6  4  HTH_32          Homeodomain-like domain
       0.13   12.2   0.0       0.26   11.2   0.0    1.5  1  NTase_sub_bind  Nucleotidyltransferase substrate binding prot


Domain annotation for each model (and alignments):
>> DDE_3  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.1   0.1   5.5e-16     2e-12      76     145 ..     242     307 ..     227     308 .. 0.85

  Alignments for each domain:
  == domain 1  score: 47.1 bits;  conditional E-value: 5.5e-16
       DDE_3  76 lqakkivlilDnasiHkseslrelveeeadrlellylPpySPelNpiEivwsklkrellkrrsfksldeL 145
                 +q++ + l  D+a+ H s++ ++ ++e   ++  +y+P+ SP+lNpiE vw+++k+++++  ++++ ++L
  EEA22114.1 242 QQSIYLQLMQDGAPGHASKETKKELQE--RNIYPIYWPAFSPDLNPIEAVWNWMKDWIQE--QYPNDEQL 307
                 3444666788*****************..******************************9..66666665 PP

>> HTH_Tnp_Tc3_2  Transposase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.9   0.5   4.4e-13   1.6e-09       8      72 .]      85     146 ..      81     146 .. 0.92

  Alignments for each domain:
  == domain 1  score: 37.9 bits;  conditional E-value: 4.4e-13
  HTH_Tnp_Tc3_2   8 vrkdPritlreLanelkeeGksvsreTirrrLrkaglkkrkprkkplLskknrkaRLeFAkehln 72 
                     ++ +r+ + ++++el      + ++   r L+k g+  +k+ +kp+Ls ++++ RL++A+eh+n
     EEA22114.1  85 SKRTRRMPYYKVIREL---DLPIGATALARALKKRGYTRCKALRKPPLSDEHKRVRLAWALEHVN 146
                    5778888888999999...999999999***********************************97 PP

>> HTH_12  Ribonuclease R winged-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   5.9e-06     0.021       5      36 ..      95     125 ..      93     127 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 5.9e-06
      HTH_12   5 kilaesdkpigakeiaeeLkkrgydigeravR 36 
                 k++ e d piga ++a  Lkkrgy    +a+R
  EEA22114.1  95 KVIRELDLPIGATALARALKKRGYTR-CKALR 125
                 6999********************86.67777 PP

>> HTH_32  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.1      0.12   4.1e+02      15      49 ..      16      53 ..      12      58 .. 0.71
   2 ?   13.0   0.6   3.3e-05      0.12      18      56 ..      59     113 ..      49     120 .. 0.66
   3 ?    2.7   0.7     0.054   1.9e+02      17      56 ..     113     156 ..     105     165 .. 0.67
   4 ?   -2.7   0.1       2.8   9.9e+03      53      60 ..     294     301 ..     289     319 .. 0.47

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.12
      HTH_32 15 egLkdrprrg..rpr..klsdevrariiallreeprWsp 49
                eg ++++++g  +p   +l+ + r ri+ l+ e+ ++++
  EEA22114.1 16 EGAREAASGGesKPYstRLNRDDRIRILTLR-EAVQYTC 53
                566666666664553778************9.6545555 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 3.3e-05
      HTH_32  18 kdrprrgrprklsdevrariiallreep.................rWsprqlaarl 56 
                  +++ rgr++kls+e ++r+i+++   +                   ++  la++l
  EEA22114.1  59 TPKKARGRTPKLSEEDVDRVIDWIS-SSkrtrrmpyykvireldlPIGATALARAL 113
                 689999******************4.332455444444444433333555555555 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.054
      HTH_32  17 Lkdrprrg........rprklsdevrariiallreeprWsprqlaarl 56 
                 Lk r   g        +p+ lsde+++  +a++ e+  W+ +q  + l
  EEA22114.1 113 LKKR---GytrckalrKPP-LSDEHKRVRLAWALEHVNWTIEQWNRIL 156
                 4444...222223341444.999999999999977889*999976655 PP

  == domain 4  score: -2.7 bits;  conditional E-value: 2.8
      HTH_32  53 aarlaere 60 
                  ++++e++
  EEA22114.1 294 KDWIQEQY 301
                 33443333 PP

>> NTase_sub_bind  Nucleotidyltransferase substrate binding protein like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   7.4e-05      0.26      42      72 ..     287     320 ..     285     340 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 7.4e-05
                     HHHHHHHHHHHHHHTSSSCCTTT...HHHHHHHH CS
  NTase_sub_bind  42 Elawkllkryleeegisaeavsp...rdliReaa 72 
                     E  w+++k++++e+  ++e++s    r+++R + 
      EEA22114.1 287 EAVWNWMKDWIQEQYPNDEQLSYdrlREVVRASW 320
                     899**********999999988788999999865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (352 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       485  (0.0270511); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.56u 0.23s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 2418.00
//
Query:       EEA22115.1  [L=392]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (392 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       489  (0.0272742); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.24s 00:00:00.70 Elapsed: 00:00:00.40
# Mc/sec: 2971.47
//
Query:       EEA22116.1  [L=768]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.2e-17   61.1   0.2    1.9e-16   59.9   0.0    1.6  2  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.9   0.0     1e-20   1.9e-16       3     176 ..     237     413 ..     236     478 .. 0.86
   2 ?   -3.2   0.1      0.18   3.3e+03     110     132 ..     534     559 ..     530     563 .. 0.82

  Alignments for each domain:
  == domain 1  score: 59.9 bits;  conditional E-value: 1e-20
  Fungal_trans   3 rffsnfhpqfpilhkpsflpkt...ssenssksayasplll.............lailalGalfsesetkesnssltsesqefiafplraeilihed 83 
                   +++  +h+  pi+h++ f++ +   +se++++ ++    ll             ++ lal+  ++++ +++ n  +t       af+ rae l+ +d
    EEA22116.1 237 SYWNEIHSMNPIFHEQIFMKRYnrlFSEGPTIRPSRTGSLLevellpcdrifqaTLNLALAIVYLRTSSGTPNDHETAQE----AFFDRAERLLTPD 329
                   7************************7777777777777777777778888887888899999999999998877777644....8888******99* PP

  Fungal_trans  84 fsspssslwilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppll 176
                   +    s l+ +q+L+l ++y+   +  +  +  +gva+r a+ +gL  +  ++g      +++e +e+rrR+w+a+ ++D+t ++ +Grpp++
    EEA22116.1 330 LMQLES-LQLVQALVLKATYLREADMSNRSWIAVGVAIRTAQAIGLYVEN-NKG------SQAE-REQRRRVWYACVIMDRTQSMTYGRPPMI 413
                   999999.****************************************665.556......6777.**************************53 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 0.18
  Fungal_trans 110 ralher...hhgvavrlarslgLhrn 132
                   + lh+r   ++g+ v +ar+ + + +
    EEA22116.1 534 QFLHWRlvlFRGLLVDFARESSSSLH 559
                   5799**999*******9998876655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (768 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       574  (0.0320152); expected 358.6 (0.02)
Passed bias filter:                      436  (0.0243181); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.64u 0.30s 00:00:00.94 Elapsed: 00:00:00.47
# Mc/sec: 4935.85
//
Query:       EEA22117.1  [L=1043]
Description: arylsulfatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   1.3e-126  422.2   0.1    9.2e-65  219.0   0.0    2.1  2  Sulfatase     Sulfatase
    1.7e-22   79.6   6.2    2.7e-19   69.3   1.6    3.4  3  DUF4976       Domain of unknown function (DUF4976)
    6.9e-08   32.5   0.3        0.1   12.2   0.0    4.1  4  Phosphodiest  Type I phosphodiesterase / nucleotide pyrophosp
     0.0024   18.6   1.0        1.3    9.8   0.0    3.3  2  Sulfatase_C   C-terminal region of aryl-sulfatase
  ------ inclusion threshold ------
      0.015   14.0   0.0        4.3    5.8   0.0    2.3  2  DUF229        Protein of unknown function (DUF229)
      0.081   12.8   0.1       0.69    9.9   0.0    2.6  2  DUF4994       Domain of unknown function


Domain annotation for each model (and alignments):
>> Sulfatase  Sulfatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  219.0   0.0   3.1e-68   9.2e-65       1     278 [.      19     413 ..      19     414 .. 0.95
   2 !  201.0   0.1   9.3e-63   2.8e-59       1     307 [.     518     895 ..     518     897 .. 0.92

  Alignments for each domain:
  == domain 1  score: 219.0 bits;  conditional E-value: 3.1e-68
                 EEEEEEEESSE-TTGSGGGTTTSCSSHHHHHHHHTSEEESSEE-SSSSHHHHHHHHHHSS-HHHHTHSSCCSTTT.............HHCTTTS-HHH CS
   Sulfatase   1 pnvvliladdlgagdlglyggktattpnldrlaeeglrftnfysaaplcspsraalltgryphnsgvasntevgg.............gglpqteatLp 86 
                 pn+++iladdlg++d   ygg++a tpnl++la egl  t+f++aa +csp+ra+ll+g ++h +g ++++e                g l+ ++a+Lp
  EEA22117.1  19 PNFLIILADDLGFSDTAPYGGEIA-TPNLQKLASEGLCMTDFHTAA-SCSPTRAMLLSGTDAHIAGLGAMQERMRkfpeifkdrpgyeGYLNFRVAALP 115
                 9**********************9.9*****************997.*********************99998889*********************** PP

                 HHHHHTT-EEEEEEES-SCCSGGGSHHCCTTTSEEEETSSSCHHTCCCCCCCCCECTCCC.....................TTTTCSHHHHHHHHHHHH CS
   Sulfatase  87 ellkeaGYntaaigkwhlgwssrqsvyknrgfdrflgfptgsaalkdpekseyngevlrv.....................ppeggysddrlldealef 164
                 e+l+++GY t + gkwhlg++++ +++ +rgf ++++  +g+ +++++e + y  +                          p+ +ys++ ++d +l f
  EEA22117.1 116 EILQDNGYLTMMSGKWHLGLTKEVAPC-SRGFTKVFSTLPGAGNHYNHEPQLYEKPK--AlfkgnkglwmkddefidgetdLPKDFYSSNFFTDSLLSF 211
                 ************************965.57****99999999999998866665544..3559************************************ PP

                 H...HCCC.TSSEEEEEEE-TTSSSTCTCGGHTCCGSTTTTCCCCCCH..........................................HHHHHHHHH CS
   Sulfatase 165 l...larn.dkpfflylatlapHappeapdeyakkyatffddgseaar..........................................qlleaylns 217
                 l    +++ ++pff+yla+ apH+p++ap+e ++ky++++ddg+ a r                                          +++e+y+++
  EEA22117.1 212 LknrNDSQkEQPFFSYLAFTAPHWPLQAPPEVVEKYRGWYDDGPLALRdrrlkslierglvpedvepaplhtmnttpwtelsdeekkkssRAMEVYAAM 310
                 *999555559************************************9999999999******************************************* PP

                 HHHHHHHHHHHHHHHHHTTTGGGEEEEEEESSSSCCCG...........................................HHTTSSSCTTCSSSHHHH CS
   Sulfatase 218 veyvDdligrvlaaLeenglldntlvvftSDhgaslee...........................................sngplrggkganayeggt 273
                 v  +D +igrv+++Le +g+ldnt++vf+SD+ga+ +                                            s++p rg k+  ++egg+
  EEA22117.1 311 VDLIDVNIGRVYDYLESTGELDNTFIVFMSDNGAEGNLleaipvlagatlddvikkycnnslenignhdsfvwygpqwasaSTAPSRGAKS-YTTEGGI 408
                 **********************************6644*****************************************************.******* PP

                 BEEEE CS
   Sulfatase 274 rvPll 278
                 r P++
  EEA22117.1 409 RCPCI 413
                 ***97 PP

  == domain 2  score: 201.0 bits;  conditional E-value: 9.3e-63
                 EEEEEEEESSE-TTGSGGGTTTSCSSHHHHHHHHTSEEESSEE-SSSSHHHHHHHHHHSS-HHHHTHSSCCSTTTHHCTTTS-HHHHHHHHT.T-EEEE CS
   Sulfatase   1 pnvvliladdlgagdlglyggktattpnldrlaeeglrftnfysaaplcspsraalltgryphnsgvasntevgggglpqteatLpellkea.GYntaa 98 
                 pn+++i+add  a+ +++yg   + tpnldr+a+eg+rf+  y++ + c+psra++ltg  +h +gv +      + l ++ +++++ l+ a GY+ta+
  EEA22117.1 518 PNIIFIMADDHAAKAISCYGADLNQTPNLDRIATEGMRFNHCYVTNSICTPSRATILTGTHNHVNGVRTLA----SVLDNRLPNVAKQLRVAgGYQTAL 612
                 9***************************************************************9976666....9**************9999***** PP

                 EEES-SCCSGGGSHHCCTTTSEEEETSSSCHHTCCCCCCCCCECTCCCTTTTCSHHHHHHHHHHHHHHCCC.TSSEEEEEEE-TTSSSTCTCGGHTCCG CS
   Sulfatase  99 igkwhlgwssrqsvyknrgfdrflgfptgsaalkdpekseyngevlrvppeggysddrlldealefllarn.dkpfflylatlapHappeapdeyakky 196
                 +gkwhlg  +        gfd ++++ +g+ ++ dp+  e  ++v     e+gy +d+++d+ +e++++r+ + pffl+ +  apH  +e+ +++ + y
  EEA22117.1 613 VGKWHLGEGKAHE---PTGFD-YWSVLPGQGDYHDPKMIEMGTPV----AEQGYATDIITDKSIEWIKRRDpSGPFFLMCHHKAPHRSWEYHPKHKGLY 703
                 *******997777...68***.77889999999999999999999....59****************99999***************998888888886 PP

                 STTTTCCCCCCH......................................................................................H CS
   Sulfatase 197 atffddgseaar......................................................................................q 209
                 ++     +  ++                                                                                      +
  EEA22117.1 704 QDD---IKIPDTftddyknraraaavtkmrvaddltykdlslvqpeggnevgeplfpgsrerkipnpadvtglilldretgakytfetsqqlaefkfqR 799
                 543...222222444566667789999999999****************************************************************** PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHTTTGGGEEEEEEESSSSCCCGHHTTSSSCTTCSSSHHHHBEEEEEEETTTSHC..EEECSEEEGGGHHHHHHHH CS
   Sulfatase 210 lleaylnsveyvDdligrvlaaLeenglldntlvvftSDhgasleesngplrggkganayeggtrvPllvwwpgekap..rvseelvshiDlfptildl 306
                 ++  yl++++++D+++gr l+ L+ + l ++t+v++tSD g  l+e  + +   k+  +ye++++ P+l+++p+e+++   +++ ++s++ ++pt+l+l
  EEA22117.1 800 YMKRYLRTIASIDENVGRMLDFLDVEDLTNDTVVIYTSDQGFFLGE--HGF-FDKR-FMYEESFQMPFLIRYPREIPAgrVNDKDIISNVGFAPTFLHL 894
                 ********************************************66..444.4455.7*********************77778899***********9 PP

                 T CS
   Sulfatase 307 a 307
                 a
  EEA22117.1 895 A 895
                 8 PP

>> DUF4976  Domain of unknown function (DUF4976)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       1.3   3.9e+03       8      37 ..     206     234 ..     202     237 .. 0.85
   2 !   10.4   0.0    0.0002      0.61      61      80 ..     439     458 ..     432     476 .. 0.79
   3 !   69.3   1.6   9.1e-23   2.7e-19       1      99 [.     899    1010 ..     899    1014 .. 0.85

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 1.3
     DUF4976   8 ksllpllkgkkkkewrkalyYhyyeyPaeh 37 
                 +sll  lk +++++++++ ++ y  + a+h
  EEA22117.1 206 DSLLSFLK-NRNDSQKEQPFFSYLAFTAPH 234
                 58889999.888999999999999988877 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.0002
     DUF4976  61 ewelyDlkkDpkelknlydd 80 
                 +welyD+ kD+ e+++l d 
  EEA22117.1 439 KWELYDISKDKGEIHDLADA 458
                 8**************99875 PP

  == domain 3  score: 69.3 bits;  conditional E-value: 9.1e-23
     DUF4976    1 ipadmqGksllpllkgkkkkewrkalyYhyyeyPa.ehavkrhygvrteryklihfykd............idewelyDlkkDpkelknlyddpeye 84  
                  +p+ mqG s++pll+g ++++w++ +y +y+ +     ++  hyg+r++rykli +y++            ++ewel+D ++Dp el n yddp+y+
  EEA22117.1  899 VPTYMQGVSFRPLLQGCTPSDWQQVAYHRYWMHKDcFSNAYAHYGIRDQRYKLIYWYNEglglegtqpggeEKEWELFDCEEDPLELFNSYDDPRYA 995 
                  5999**************************98754267899****************85433333333333689*********************** PP

     DUF4976   85 evvkelkkkleelrk 99  
                  +vv+ +++kl+++  
  EEA22117.1  996 DVVRLMTEKLNRKML 1010
                  **********98765 PP

>> Phosphodiest  Type I phosphodiesterase / nucleotide pyrophosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0     0.041   1.2e+02       2      37 ..      22      60 ..      21      74 .. 0.81
   2 ?    2.4   0.0     0.031        92     199     235 ..     309     345 ..     289     393 .. 0.86
   3 !   10.3   0.0   0.00013      0.38      19      63 ..     541     584 ..     526     587 .. 0.92
   4 !   12.2   0.0   3.4e-05       0.1     197     234 ..     804     841 ..     696     880 .. 0.91

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.041
                  EEEEETT-BTTHHHHHG.S.TSHHHHHHHHHSEEESE.E CS
  Phosphodiest  2 lvislDGlradlldrla.e.llpnlaaLakegvsapn.l 37
                  l+i+ D l ++   ++  e ++pnl++La+eg+  +  +
    EEA22117.1 22 LIILADDLGFSDTAPYGgEiATPNLQKLASEGLCMTDfH 60
                  67888889999999998889************9887644 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.031
                   HHHHHHHHHHHHHHHHHHHTTGTTTEEEEEEES---E CS
  Phosphodiest 199 dalrrvDkaigdLlealderglsaetniilvSDHGma 235
                   + +  +D +ig+ +++l+ +g  ++t i+ +SD G++
    EEA22117.1 309 AMVDLIDVNIGRVYDYLESTGELDNTFIVFMSDNGAE 345
                   5667799*************9999999******9987 PP

  == domain 3  score: 10.3 bits;  conditional E-value: 0.00013
                   STSHHHHHHHHHSEEESEEE-SSS-SHHHHHHHHHHSS-HHHHS- CS
  Phosphodiest  19 ellpnlaaLakegvsapnlrpvfPtlTfpnhaslvTGlyPgeHGi 63 
                   + +pnl+++a eg ++  +  v +++  p+ a+++TG++   +G+
    EEA22117.1 541 NQTPNLDRIATEGMRFN-HCYVTNSICTPSRATILTGTHNHVNGV 584
                   58***************.999****************99888886 PP

  == domain 4  score: 12.2 bits;  conditional E-value: 3.4e-05
                   HHHHHHHHHHHHHHHHHHHHHTTGTTTEEEEEEES--- CS
  Phosphodiest 197 vedalrrvDkaigdLlealderglsaetniilvSDHGm 234
                    + +++++D+++g++l+ ld + l+++t +i +SD G+
    EEA22117.1 804 YLRTIASIDENVGRMLDFLDVEDLTNDTVVIYTSDQGF 841
                   567899*******************************9 PP

>> Sulfatase_C  C-terminal region of aryl-sulfatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.3     0.021        64      15      70 ..     419     456 ..     411     478 .. 0.56
   2 !    9.8   0.0   0.00044       1.3      16     106 ..     943    1024 ..     925    1035 .. 0.77

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.021
                  CEEEETTEEEECEE--GCGTT-GGGTTTSSSTT-EEECCEEEEETTT-TT--S-TT CS
  Sulfatase_C  15 hAvRlgkyKahfvtpsfdpegaegcygsecvekvtehdpPllFdlerDpsEkypls 70 
                   AvR+gk+K  +  p   p ++                   l+d+++D +E ++l+
   EEA22117.1 419 AAVRVGKWKGVYLPPPRGPGKW------------------ELYDISKDKGEIHDLA 456
                  5666666666666522222222..................2555555555555555 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00044
                   EEEETTEEEECEE--GCGTT-GGGTTTSSSTT-EEECCEEEEETTT-TT--S-TTSTTCCHHHHHHHHHHHHHHHCCC------TCCHHCH CS
  Sulfatase_C   16 AvRlgkyKahfvtpsfdpegaegcygsecvekvtehdpPllFdlerDpsEkyplsaespeykevlkeikkaveehkktlkpvpnqlakgel 106 
                    +R ++yK+ ++     +eg  g +g++   +  e ++  lFd e+Dp E ++   ++p+y++v++ +++ +++   ++   p  + +++ 
   EEA22117.1  943 GIRDQRYKLIYWY----NEG-LGLEGTQ---PGGEEKEWELFDCEEDPLELFNSY-DDPRYADVVRLMTEKLNRKMLEIGDEPLHMHELTT 1024
                   588899****999....333.3344444...566788889************988.67********9999999888888777777776655 PP

>> DUF229  Protein of unknown function (DUF229)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0    0.0014       4.3     310     344 ..     310     344 ..     297     427 .. 0.81
   2 ?    5.6   0.1    0.0017       5.1     301     371 ..     798     870 ..     782     876 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0014
      DUF229 310 llealDedllkylkklekkgllentlvlllsDHGl 344
                 ++  +D ++ ++   le  g l+nt+++++sD G 
  EEA22117.1 310 MVDLIDVNIGRVYDYLESTGELDNTFIVFMSDNGA 344
                 55556666666777789999************994 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0017
      DUF229 301 nslshdkfnllealDedllkylkklekkgllentlvlllsDHGlrfgklrkts.qGilEerlPl.mlirlPpw 371
                 +    +++  +  +De++ ++l  l+ ++l ++t+v+  sD G   g++  +    + Ee+ ++ +lir+P+ 
  EEA22117.1 798 QRYMKRYLRTIASIDENVGRMLDFLDVEDLTNDTVVIYTSDQGFFLGEHGFFDkRFMYEESFQMpFLIRYPRE 870
                 44567889999999******************************99999999845567888777456788876 PP

>> DUF4994  Domain of unknown function
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0   0.00023      0.69      69      94 ..     441     466 ..     418     469 .. 0.94
   2 ?   -1.4   0.0      0.75   2.2e+03      63      84 ..     968     989 ..     941    1004 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00023
     DUF4994  69 qLydlkkdegekenvaekhpekvkel 94 
                  Lyd++kd+ge +++a+ +p+k+ e+
  EEA22117.1 441 ELYDISKDKGEIHDLADAYPDKMAEM 466
                 69*********************998 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.75
     DUF4994  63 GnskepqLydlkkdegekenva 84 
                 G++ke  L+d ++d+ e  n  
  EEA22117.1 968 GEEKEWELFDCEEDPLELFNSY 989
                 8889999*******99988764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1043 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       423  (0.0235931); expected 358.6 (0.02)
Passed bias filter:                      410  (0.022868); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.78u 0.30s 00:00:01.08 Elapsed: 00:00:00.48
# Mc/sec: 6541.97
//
Query:       EEA22118.1  [L=529]
Description: sugar transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-77  261.6  19.9    1.5e-77  261.4  19.9    1.0  1  Sugar_tr         Sugar (and other) transporter
    1.9e-13   50.1  18.0    1.9e-13   50.1  18.0    2.1  2  MFS_1            Major Facilitator Superfamily
    2.4e-10   39.5   2.8    3.9e-10   38.8   2.8    1.2  1  TRI12            Fungal trichothecene efflux pump (TRI12)
  ------ inclusion threshold ------
       0.66   10.6   5.5       0.37   11.4   2.7    2.0  2  Phage_holin_3_2  Phage holin family 2


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  261.4  19.9   3.3e-81   1.5e-77       3     452 .]      21     468 ..      18     468 .. 0.92

  Alignments for each domain:
  == domain 1  score: 261.4 bits;  conditional E-value: 3.3e-81
                 HHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS CS
    Sugar_tr   3 lvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgkns 101
                 ++++++ + fg     +++++++  f+++fg  ++++++  + + ++ + ++  +  ++G l++g +++r+GR+++++ + ++++ig++++++a+   +
  EEA22118.1  21 FLMSISVFNFGLENTAYSTIQAMDPFINRFGTLRKNGKYVITPKHLSYLSAFPRITFAAGILIGGRISERVGRRPVIVLMMIICLIGTIVSYTAE---T 116
                 667777799**************************9999988999999999999*****************************************...9 PP

                 -TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHH CS
    Sugar_tr 102 vevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPrylve 200
                 + + ++gR++v  ++G++ ++vPm+++Ei+p+++Rg++v  y +  +fG ++ +++++++++ + +  w+i++++ +v++ l+l+l +flPESPr+l+ 
  EEA22118.1 117 FAAALIGRMIVNGYAGMEGCVVPMFQAEISPAAIRGIVVISYLFNHVFGSFIMSCITYKTADLKTDMSWKIPIAVMFVIPCLVLLLSWFLPESPRWLLR 215
                 ***************************************************************999********************************* PP

                 TT-HHHHHHHHHHHHHC...HHHHHHHHHHHHHHHHHHH.....HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THHHHHHHHH CS
    Sugar_tr 201 kgkeeeakevlaklrge...edadrelaeekdsleaeqeeekaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsksllvtiiv 296
                 kg++e+a + l+ l g+   +  +re++  k+sl a   +++ +w  ll+  t+++r++i+v +q+f qltG  + + y+++++++lg  +++ +t+i 
  EEA22118.1 216 KGRDEDALKQLKYLYGSddqARLEREIELLKESLAAD--TQEGTWMDLLRG-TNLRRTIIVVFIQSFNQLTGQTFATSYGTVFIKSLGTINPFKFTLIS 311
                 *************777722233444555555555555..3379********.56********************************************* PP

                 HHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHH CS
    Sugar_tr 297 gvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavn 395
                  ++  +  f  +flvdr+GRR+++l+ ++ +  c++++g+  l +v+ +   + +++++ +l+ +++ +++g++  ++ +E+ ++++R+k + +    +
  EEA22118.1 312 HAIGCLGPFLTFFLVDRLGRRYMYLIFGTLCGSCLFVMGGLGLGTVNFQ--QKAGIVAMDILYPFFYCFSFGGMSPLTGAEVPSPKLRDKSAVVGWSFQ 408
                 **************************************95555555554..5677778889999999999***************************** PP

                 HHHHHHHHHHHHHHHCHHH...T-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 396 wlanflisllfpiiteaig...ggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 +l+ f+++++ p++ + +    +  v+++f++++vl++++ +ff+pe kgr+leei+e f
  EEA22118.1 409 NLWAFVVTFVVPYLISDSYaglQSRVGFIFGSICVLGLVWAYFFFPELKGRSLEEIDEFF 468
                 *************998877677789*******************************9976 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.1  18.0   4.3e-17   1.9e-13       4     315 ..      17     384 ..      16     393 .. 0.65
   2 !    9.3  15.0   0.00011      0.49      46     178 ..     316     459 ..     307     492 .. 0.73

  Alignments for each domain:
  == domain 1  score: 50.1 bits;  conditional E-value: 4.3e-17
       MFS_1   4 aaflsalarsilgpalpl.alaed.........lg.........ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfas 83 
                 a+++  +++s++++ l   a+++          +g         i+p  ++ l ++  +++a+++l++Gr+s+r+Grr+v++l++++ ++g ++ ++++
  EEA22118.1  17 AFCIFLMSISVFNFGLENtAYSTIqamdpfinrFGtlrkngkyvITPKHLSYLSAFPRITFAAGILIGGRISERVGRRPVIVLMMIICLIG-TIVSYTA 114
                 55666666666666665433322233333333322555555666***********************************************.8888765 PP

       MFS_1  84 slw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg...Wravfyilaivsllafvlfllllpeeppe 178
                   + + l++r++    ag+   ++  + a+++p   rg ++  +     +G+ +   +    a++     W  +  ++ ++ +l+++l  ++   ++++
  EEA22118.1 115 ETFaAALIGRMIVNGYAGMEGCVVPMFQAEISPAAIRGIVVISYLFNHVFGSFIMSCITYKTADLKTdmsWKIPIAVMFVIPCLVLLL-SWF--LPESP 210
                 5555999999988888899999999999999999999999988888888888888888887775544788****99999999998774.344..56666 PP

       MFS_1 179 rkrkspkeee...........................kgtgpaplvp....awkallkdpvlwillialllfffgfsglltllplylqevlgls....g 242
                 r+  ++ ++e                           +      +++     w  ll+   l   +i++++ +f   +  t+ ++y  +v+  s    +
  EEA22118.1 211 RWLLRKGRDEdalkqlkylygsddqarlereiellkeS-----LAADtqegTWMDLLRGTNLRRTIIVVFIQSFNQLTGQTFATSY-GTVFIKSlgtiN 303
                 6666666666669******9999988877776433322.....2222667779999999988756666666654555544444445.444444442222 PP

       MFS_1 243 lllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavt.....ssavllll.....vlvliGf.glg 315
                  +  +    ++ ++g+ + +l+ +l+drlgrr + l+++ l+  +++ +  l++      ++a ++++     ++++++f g++
  EEA22118.1 304 PFKFT---LISHAIGCLGPFLTFFLVDRLGRRYMYLIFGTLCGSCLFVMGGLGLGtvnfqQKAGIVAMdilypFFYCFSFgGMS 384
                 34444...4444444444777777779999755555544444444444444443366664333333334444455555554444 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.00011
       MFS_1  46 avaslplGrlsdrfGrrrvlllglllfalglllll.fa......sslwl...llvlrvlqGlgagalfpagaaliadwfpke..ergraigllsagfsl 132
                 +++ +++ +l+dr+Grr ++l+  +l +++l+++  ++      +       ++++ +l  ++++++f ++  l+ + +p +  +  +a+  +s  +  
  EEA22118.1 316 CLGPFLTFFLVDRLGRRYMYLIFGTLCGSCLFVMGgLGlgtvnfQ---QkagIVAMDILYPFFYCFSFGGMSPLTGAEVPSPklRDKSAVVGWSFQNLW 411
                 5666677999********999999999999444445534343431...2445***************************99723334555666667779 PP

       MFS_1 133 Gailgpllgglla.sslg.Wravfyilaivsllafvlfllllpeeppe 178
                 +++++ ++  l++ s++g  + v +i++ +++l++v +++++pe + +
  EEA22118.1 412 AFVVTFVVPYLISdSYAGlQSRVGFIFGSICVLGLVWAYFFFPELKGR 459
                 99999********77777644478899999999977666666554443 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.8   2.8   8.7e-14   3.9e-10      83     237 ..      69     224 ..      57     230 .. 0.71

  Alignments for each domain:
  == domain 1  score: 38.8 bits;  conditional E-value: 8.7e-14
       TRI12  83 fstlwttgqavsilvmgrltdrfgrrpfvilthilglvgaivgctatkfnt.llaamtllgvaagpagasplfvgelmsnktkflgllivs..ipvvvt 178
                 +s++  +  a  il+ gr+++r+grrp+++l  i+ l+g+iv  ta+ f + l+  m + g a       p+f  e+     +  g++++s     v  
  EEA22118.1  69 LSAFPRITFAAGILIGGRISERVGRRPVIVLMMIICLIGTIVSYTAETFAAaLIGRMIVNGYAGMEGCVVPMFQAEISPAAIR--GIVVISylFNHVFG 165
                 566667778999*************************************862556677777777777789******9877665..55555511344444 PP

       TRI12 179 sglspylg.qrlaiqgswrwifyiyiitsaiavllivvwyyppsfaqlhgkkvrkreela 237
                 s +   +  +   ++ +  w + i ++    +++l++ w+ p s + l   k r  + l 
  EEA22118.1 166 SFIMSCITyKTADLKTDMSWKIPIAVMFVIPCLVLLLSWFLPESPRWLLR-KGRDEDALK 224
                 43333333033445666666666776666667889999****99988864.455555555 PP

>> Phage_holin_3_2  Phage holin family 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   2.7   8.2e-05      0.37      14      68 ..     102     154 ..      92     159 .. 0.77
   2 ?   -3.4   0.0       3.4   1.5e+04      43      73 ..     406     436 ..     399     443 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 8.2e-05
  Phage_holin_3_2  14 iGalialGklLvseepitlrLfiGRvilGsavslvagvaLvqfpdlsplavvGig 68 
                      i  +  +G ++    +  +  +iGR+i+ + + +   v+ +   ++sp a+ Gi 
       EEA22118.1 102 I--ICLIGTIVSYTAETFAAALIGRMIVNGYAGMEGCVVPMFQAEISPAAIRGIV 154
                      3..44456666655555556679******************************95 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 3.4
  Phage_holin_3_2  43 savslvagvaLvqfpdlsplavvGigsalGi 73 
                      s+  l a v+  ++p l   + +G+ s +G 
       EEA22118.1 406 SFQNLWAFVVTFVVPYLISDSYAGLQSRVGF 436
                      5556777788888888888888888888884 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (529 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       852  (0.0475208); expected 358.6 (0.02)
Passed bias filter:                      502  (0.0279993); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.65u 0.30s 00:00:00.95 Elapsed: 00:00:00.48
# Mc/sec: 3322.56
//
Query:       EEA22119.1  [L=379]
Description: hypothetical protein PMAA_058990 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
     0.0097   16.4   2.5      0.023   15.2   0.0    2.7  3  DUF4231       Protein of unknown function (DUF4231)
  ------ inclusion threshold ------
       0.07   13.1   0.5        0.2   11.6   0.1    2.0  2  LRR19-TM      Leucine-rich repeat family 19 TM domain
       0.19   11.5   3.5       0.62    9.8   0.2    2.8  3  Trp_oprn_chp  Tryptophan-associated transmembrane protein (Tr
       0.64    9.2  10.8      0.013   14.7   3.2    2.0  3  Lung_7-TM_R   Lung seven transmembrane receptor
        2.9    7.5  16.1      0.087   12.5   4.4    3.1  4  DUF1345       Protein of unknown function (DUF1345)


Domain annotation for each model (and alignments):
>> DUF4231  Protein of unknown function (DUF4231)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.1      0.83     3e+03       3      36 ..      30      59 ..      28      89 .. 0.60
   2 ?   -0.7   0.1      0.54   1.9e+03      51      53 ..     174     176 ..     118     219 .. 0.66
   3 !   15.2   0.0   6.4e-06     0.023       9      80 ..     251     347 ..     243     369 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.83
     DUF4231  3 lswyekkasrakrrfrllrlitivlgallpilvs 36
                +sw+ +k+sr k +      +  v++ llp++++
  EEA22119.1 30 ISWTFNKSSRHKDTIS----VDFVAALLLPLIAA 59
                5677777777776666....56666666676666 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.54
     DUF4231  51 all 53 
                 +++
  EEA22119.1 174 WAC 176
                 111 PP

  == domain 3  score: 15.2 bits;  conditional E-value: 6.4e-06
     DUF4231   9 kasrakrrfrllrlitivlgallpilvs............................sklgagvsvlkiltallsalvailaaleeffrykerWrryRst 79 
                 + +++  rfr+l ++t v+ +++p+ +                              ++ ++ s l  ++al++ ++++laa+ + ++ ke    ++s+
  EEA22119.1 251 SDRHSEIRFRSLEMMTFVGLFFAPLSAIlslistfdsfsamrknssalysgrflliPQSDVSMSNLDQIAALVGGVIVLLAAIRSAYHSKE---DNKSA 346
                 5578889999999999999999998888889***********************99778899999999********************999...55555 PP

     DUF4231  80 a 80 
                 +
  EEA22119.1 347 S 347
                 5 PP

>> LRR19-TM  Leucine-rich repeat family 19 TM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       1.1   3.8e+03       8      41 ..      39      72 ..      33      92 .. 0.72
   2 ?   11.6   0.1   5.7e-05       0.2       5      81 ..     152     228 ..     148     245 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 1.1
    LRR19-TM  8 keksgksWaylvgvvvlalvtsllillaikckll 41
                ++k   s  +++++ +  +    l++l i+ ++ 
  EEA22119.1 39 RHKDTISVDFVAALLLPLIAAGHLVFLLIRLPVS 72
                5555667778888888888888889988887765 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 5.7e-05
    LRR19-TM   5 aaekeksgksWaylvgvvvlalvtsllillaikckllykfllsYrHrrLeeseaetyeegltenrnslseasdtnse 81 
                 +a ++++++ + +lv+ +v  +  +l+i + +   ++  + ++ r  + ++ +++t++e+ te   s+ +++  ++e
  EEA22119.1 152 NARETTLSRPYLFLVTTIVASTWACLVICVLVGSLTWVISSINARRAQNKDGRQDTADEKRTEWIMSIAHLKASKKE 228
                 5667888999***************************8877777777777777999999999988888888877777 PP

>> Trp_oprn_chp  Tryptophan-associated transmembrane protein (Trp_oprn_chp)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.3      0.84     3e+03      24      48 ..      37      60 ..      17      82 .. 0.52
   2 ?    2.0   0.1     0.044   1.6e+02     116     156 ..     167     211 ..     123     241 .. 0.55
   3 ?    9.8   0.2   0.00017      0.62      71     153 ..     273     353 ..     166     356 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 0.84
  Trp_oprn_chp 24 vsdalggprtvalsGadwapaltal 48
                  +s+++  + +v++  a + p+++a 
    EEA22119.1 37 SSRHKD-TISVDFVAALLLPLIAAG 60
                  333333.444444444444444443 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.044
  Trp_oprn_chp 116 tawpvlalaggvllllagvllllra....rswpamssrYerpaar 156
                   t+ ++ + a  v+++l g l+++ +    r+++++ +r ++++++
    EEA22119.1 167 TTIVASTWACLVICVLVGSLTWVISsinaRRAQNKDGRQDTADEK 211
                   333333333333344444443333311113333333444443333 PP

  == domain 3  score: 9.8 bits;  conditional E-value: 0.00017
  Trp_oprn_chp  71 gvllalagagaavaalslltdpadaaraaa.aaatgvasaaaavelta.wpvlalaggvllllagvllllrarsw.pamssrYerp 153
                   + l a+++++ ++ ++s+++++++a ++ +      +   +++v++++   ++al+ggv++lla++  + +++++ ++ s +Y+r+
    EEA22119.1 273 APLSAILSLISTFDSFSAMRKNSSALYSGRfLL---I--PQSDVSMSNlDQIAALVGGVIVLLAAIRSAYHSKEDnKSASPKYSRH 353
                   556677777777777777777777777766443...3..334444444467899************98888866615558899986 PP

>> Lung_7-TM_R  Lung seven transmembrane receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.2         1   3.6e+03      59      95 ..      26      62 ..      22      69 .. 0.66
   2 ?   14.7   3.2   3.7e-06     0.013      54     142 ..      97     190 ..      87     201 .. 0.72
   3 ?   -2.4   0.0      0.62   2.2e+03     157     210 ..     268     292 ..     247     300 .. 0.52

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 1
  Lung_7-TM_R 59 vllgilWlfilakykkdilkiqkliaavivlkmlela 95
                 ++++i W f    + kd + + ++ a+++ l ++  +
   EEA22119.1 26 CAVSISWTFNKSSRHKDTISVDFVAALLLPLIAAGHL 62
                 5667778888888888888888777766655544444 PP

  == domain 2  score: 14.7 bits;  conditional E-value: 3.7e-06
  Lung_7-TM_R  54 malayvllgilWlfilakykkdilkiqkliaavivlkmlelafvyieYatinskGss......ievlavlasilsalkktlsrlliliislGygi 142
                  ++  +++++++W +++   +++i+k+++l  +v+++++ + a+  + +a+++ kG +      +  + +l+ ++ a   + + + +l+ sl + i
   EEA22119.1  97 ICETFSVVALFWAILCGPWWHNIMKLKRL-GLVVITGLFSWAMENVMFAMATMKGINarettlSRPYLFLVTTIVASTWACLVICVLVGSLTWVI 190
                  6788**********************874.55566666666666666666666655544333666677777777777778888888887777766 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 0.62
  Lung_7-TM_R 157 lglllfvlaevlelvresseesessakllkvllflipl.alldlffvvwifrsLq 210
                  +g                              lf+ pl a+l l+  + +f+++ 
   EEA22119.1 268 VG------------------------------LFFAPLsAILSLISTFDSFSAMR 292
                  23..............................33334434444444444444443 PP

>> DUF1345  Protein of unknown function (DUF1345)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.1       0.9   3.2e+03      80      93 ..      21      34 ..      15      41 .. 0.72
   2 ?   12.5   4.4   2.4e-05     0.087      11     100 ..      56     145 ..      46     149 .. 0.89
   3 ?    2.4   0.1     0.031   1.1e+02       8      41 ..     173     207 ..     165     227 .. 0.48
   4 ?   -3.8   0.0       2.6   9.2e+03      51      66 ..     323     338 ..     312     347 .. 0.48

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.9
     DUF1345 80 lalavatvvlsWll 93
                 +l++ +v +sW++
  EEA22119.1 21 WLLTLCAVSISWTF 34
                45677777778865 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 2.4e-05
     DUF1345  11 laalvylvlvllvllradaeelrkraeredesrvlilllvllaalaslvaivlllasakaekpaekllhlalavatvvlsWllvhtvfal 100
                 l+a+ +lv++l++l  + ae +++ra + ++ + +i + + +  ++s+va+++++      ++  kl +l+l v+t + sW++ +++fa+
  EEA22119.1  56 LIAAGHLVFLLIRLPVSLAEIITARAVELQQYESAIEAPLNICETFSVVALFWAILCGPWWHNIMKLKRLGLVVITGLFSWAMENVMFAM 145
                 456666777777777777999********************************************************************8 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.031
     DUF1345   8 gwdlaalvylv.lvllvllradaeelrkraerede 41 
                  w ++++++lv ++ +v+++++a++ +++  r+d 
  EEA22119.1 173 TWACLVICVLVgSLTWVISSINARRAQNKDGRQDT 207
                 45444444333144455555555555555444443 PP

  == domain 4  score: -3.8 bits;  conditional E-value: 2.6
     DUF1345  51 llaalaslvaivllla 66 
                 +  +++ l+ai  + +
  EEA22119.1 323 VGGVIVLLAAIRSAYH 338
                 3333333444433333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (379 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1335  (0.0744604); expected 358.6 (0.02)
Passed bias filter:                      651  (0.0363099); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.61u 0.30s 00:00:00.90 Elapsed: 00:00:00.47
# Mc/sec: 2428.93
//
Query:       EEA22120.1  [L=342]
Description: chitinase 3 precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      2e-19   70.5   0.6    5.3e-19   69.1   0.6    1.6  1  Glyco_hydro_18  Glycosyl hydrolases family 18


Domain annotation for each model (and alignments):
>> Glyco_hydro_18  Glycosyl hydrolases family 18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.1   0.6   2.9e-23   5.3e-19       2     309 ..      31     315 ..      30     319 .. 0.71

  Alignments for each domain:
  == domain 1  score: 69.1 bits;  conditional E-value: 2.9e-23
                     EEEEEEGGGGGSSG...CSH.TTTESEEEEEEEEEEE............TTTEEEESSTTHH........HHHHHHHHHH.HHTSTT-EEEEEEE CS
                     xxxxxxxxxxxxxx...xxx.xxxxxxxxxxxxxxxx............xxxxxxxxxxxxx........xxxxxxxxxx.xxxxxxxxxxxxxx RF
  Glyco_hydro_18   2 vvgYysswesygnn...ylp.saklthiiyaFakidg............engkvvvsdwedl........gnfeqlkklk.kkknpgvkvllsiG 71 
                     +v+Y++++++++++   y   ++++++ii+aF+  +g            e           +        +   ++++   k ++ g+ vlls+G
      EEA22120.1  31 TVVYWGQNSNEKADlsaYCSsTSGIDVIILAFLYEFGngidipsgvigpE-----------CyisptgqpQLCDDVTSAIaKCQAAGITVLLSLG 114
                     79****999997643554446************99997776666665551...........0344444445555666666688899********* PP

                     ETTTTTHHHHHHTSHHHHHHHHHHHHHHH.........HHCT...-SEEEEEES-TTTSTCHHHHHHHHHHHHHHHHH.HHHHHTSTTCEEEEEE CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxx.........xxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx RF
  Glyco_hydro_18  72 Gwtdssgfslaastdasrkkfadsvvsll.........rkyg...fDGiDidweypggnpedkenytallkelreald.kakategkkllLsaav 153
                     G+t   ++sl   + a++++  +++++ +         r++g   + G D+d+e+ gg     + y+ +++ lr+ +  +     g++++++ a+
      EEA22120.1 115 GATS--SYSLQ--SRAEAESIGQYLWESYgnsgnttvpRPFGsvfVNGWDFDIEVNGG---SSQYYQYMISTLRSNFAsD----PGNTYYITGAP 198
                     ***9..88888..45899999999999997777777777777************9887...4899**********88733....6999******* PP

                     ESSHHH.HHHHCHHHHHHHHTSEEEEETTTSSSTTSSBE--SS-SSBT....CSSHHHHHHHHHHT..T--GG..GEEEEEESEEEEEEESSSSS CS
                     xxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxx..xxxxx..xxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18 154 pasasd.lskgydlpkiakylDyvnvmtYDfhgswdnvtghhaplyda....slnvdeavkeylka..gvpak..klvlGvpfygrawalvsgad 239
                     +++ ++    +  +   +++ D ++v+ Y+ ++  +n    +     +      n+ + + e++ +  ++p++  kl++G p+++ a +++s   
      EEA22120.1 199 QCPLPEpN--M-SIIIGNSTFDKLWVQWYNNNNGLNNIPYES-----CslgfGGNAPFNYLEWVDFlaTTPSAnaKLYIGAPASTLASNGNSA-- 283
                     ******54..3.344445788************877722222.....1333445555555566655445663347*********877666443.. PP

                     STSTTTEEEHHHHHHHHTEEEEEEEEETTTTE.EEEEETTEEEEE-SHHHHHHHH.HHHHHTTESEEEEETG CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx RF
  Glyco_hydro_18 240 ntkeegvlsykelkellkkakakrkydskaka.pyvydgeefvsyDdpksikaka.dyvkakglgGvmiWsl 309
                                                   +a  y+          +p ++++ + +   ++ +gG+m+Ws+
      EEA22120.1 284 ------------------------------GAiYYI----------TPNEMATLVsETEGNSTFGGIMLWSA 315
                     ..............................331344..........55555555544444445666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       299  (0.0166769); expected 358.6 (0.02)
Passed bias filter:                      254  (0.014167); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2376.87
//
Query:       EEA22121.1  [L=124]
Description: DUF167 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.8e-16   57.6   0.0    1.6e-15   57.0   0.0    1.3  1  DUF167         Uncharacterised ACR, YggU family COG1872
  ------ inclusion threshold ------
      0.051   13.9   0.0      0.083   13.2   0.0    1.4  1  YgbB           YgbB family
      0.098   12.0   0.0       0.12   11.7   0.0    1.1  1  DUF4862        Domain of unknown function (DUF4862)
       0.14   12.3   0.0       0.47   10.6   0.0    1.8  2  Tautomerase_2  Tautomerase enzyme


Domain annotation for each model (and alignments):
>> DUF167  Uncharacterised ACR, YggU family COG1872
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.0   0.0   3.5e-19   1.6e-15       2      65 ..      24      84 ..      23      93 .. 0.90

  Alignments for each domain:
  == domain 1  score: 57.0 bits;  conditional E-value: 3.5e-19
                EEEEEES---SSS----...--TTTT-------TTIIIIIHHHHHHHHHHHHHS...SEEEE-S CS
      DUF167  2 vilavrvkPgakkdaigleedaegrealkvrvaappvdGkANkalikfLakalgvpksdveivs 65
                ++++++v+Pg++  + +   +++ +e++ ++va++p++G+AN+a++k+L+++lg+pksd++i  
  EEA22121.1 24 LLIRCHVTPGSRGFQGV---KKICDEQVYIHVASAPRKGEANAAVVKVLSEVLGIPKSDITIMG 84
                689*********99988...58889************************************984 PP

>> YgbB  YgbB family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   1.8e-05     0.083      98     140 ..      50      93 ..      38     102 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.8e-05
                 E.ECSSSTCGGGHHHHHHHHHHHHTS-GGGEEEEEEETTTSHHH CS
        YgbB  98 i.iaekpklapykeamrenlakllgleeeqvsvkattteklgfv 140
                 i +a++p+  + ++a+ + l+++lg++++++++  + ++k+g+v
  EEA22121.1  50 IhVASAPRKGEANAAVVKVLSEVLGIPKSDITIMGKHRDKVGQV 93 
                 4478899999******************************9765 PP

>> DUF4862  Domain of unknown function (DUF4862)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   2.7e-05      0.12     111     158 ..      48      94 ..      37     113 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 2.7e-05
     DUF4862 111 vsaveihsaPsrkasadalarSLeellswdwagaklviEHcDalvesq 158
                 v ++++ saP+++  + a+ + L+e+l++ +++  ++  H D++ + +
  EEA22121.1  48 V-YIHVASAPRKGEANAAVVKVLSEVLGIPKSDITIMGKHRDKVGQVN 94 
                 3.79**************************************987655 PP

>> Tautomerase_2  Tautomerase enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0      0.51   2.3e+03      43      53 ..      16      26 ..      12      36 .. 0.81
   2 ?   10.6   0.0    0.0001      0.47      27      72 ..      45      85 ..      34      90 .. 0.83

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.51
                   HHHHHHHHHHH CS
  Tautomerase_2 43 eqKkaLyrala 53
                   + K+aLy  l+
     EEA22121.1 16 KNKNALYSLLI 26
                   68999999886 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.0001
                   TT-EEEEEEEES---HHHHHHHHHHHHHHHHHHH---GGGEEEEEE CS
  Tautomerase_2 27 ddlvvieitlsegRseeqKkaLyralaerlaaklgirpeDvfivlv 72
                   d+ v+i++ +  +R+ e+  a ++ l e l    gi+++D+ i+ +
     EEA22121.1 45 DEQVYIHVASA-PRKGEANAAVVKVLSEVL----GIPKSDITIMGK 85
                   67799999888.999999999888887765....********9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (124 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      382  (0.0213063); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.40
# Mc/sec: 929.80
//
Query:       EEA22122.1  [L=520]
Description: dimethylaniline monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    8.6e-93  311.6   0.0    1.1e-92  311.3   0.0    1.0  1  FMO-like       Flavin-binding monooxygenase-like
    3.6e-20   72.4   0.0    3.9e-15   55.9   0.0    3.4  3  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
    5.1e-12   45.6   0.0    2.5e-09   36.8   0.0    2.4  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    1.2e-08   34.5   0.0    3.5e-06   26.4   0.0    3.1  3  K_oxygenase    L-lysine 6-monooxygenase (NADPH-requiring)
    3.5e-08   33.6   0.0    8.6e-08   32.3   0.0    1.7  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
    5.4e-06   26.5   0.1      0.033   14.2   0.0    3.6  3  NAD_binding_9  FAD-NAD(P)-binding
    0.00013   21.4   0.0    0.00053   19.4   0.0    1.9  2  Amino_oxidase  Flavin containing amine oxidoreductase
    0.00035   20.3   0.7     0.0042   16.7   0.2    2.6  3  DAO            FAD dependent oxidoreductase
    0.00044   20.7   0.0        1.3    9.6   0.0    2.5  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
     0.0029   16.7   0.0     0.0048   16.0   0.0    1.3  1  FAD_binding_2  FAD binding domain
  ------ inclusion threshold ------
      0.019   13.7   0.0       0.11   11.2   0.0    2.1  2  HI0933_like    HI0933-like protein
      0.025   13.8   0.1       0.36   10.0   0.0    2.3  2  Thi4           Thi4 family
      0.039   13.3   0.0      0.051   12.9   0.0    1.3  1  FAD_oxidored   FAD dependent oxidoreductase


Domain annotation for each model (and alignments):
>> FMO-like  Flavin-binding monooxygenase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  311.3   0.0   7.7e-96   1.1e-92       2     493 ..       9     496 ..       8     511 .. 0.88

  Alignments for each domain:
  == domain 1  score: 311.3 bits;  conditional E-value: 7.7e-96
    FMO-like   2 kkvaviGaGvsGlasikccleegleptcfersddiGGlwrfken...veeGrasiyksvvsnsskemscfsdfpl.pedypnflhnsklleylklfake 96 
                  +va+iGaG+sGl++ k cleegl pt +e    iGG w+++e    + e  +s+y  vvsn++   s fsdfp+ p +yp++  ++  l y++++a +
  EEA22122.1   9 ERVAIIGAGISGLVAAKECLEEGLLPTVYEARPYIGGQWHYEEPdslTGETFSSVYDGVVSNTCALRSQFSDFPMdPAQYPDYPTHKDYLRYIHEYAGH 107
                 59***************************************995222457789**********************6789******************** PP

    FMO-like  97 fdllkyiqfkttvcsvkkrpdfstsGqwevvtekegkkesavfdavmvctGhhvnphlplesfpGiekfkGqyfhsrdykepevfkgkrvlviGlGnsg 195
                 f+l kyi ++t v+s +k+       qw v+t++      ++f a+ +ctG    ph+p  +  G+e+f G+ +hs+ y++pev+ gkrv +iGlG s+
  EEA22122.1 108 FGLEKYILLNTGVISCDKQG-----HQWRVTTRTT----EELFGALFICTGKESVPHIP--AVTGLERFAGRAIHSHIYRQPEVYAGKRVAIIGLGSSA 195
                 ****************9975.....6*****9865....579*****************..578*********************************** PP

    FMO-like 196 gdiavelsrtaeqvllstrsGswvlsrvsdsGypwdmllvtrfksllknilptalsnwlvekklnkrfnhenyglkpkkralakepvlndelparilaG 294
                  di++e+s+ ae   l t++G+wvl r ++ G     l+ +  + l++  lp++++++ +e      +     +lkp++r l+ +pv+ +e+ + i aG
  EEA22122.1 196 VDISSEVSKHAESCHLITQRGGWVLPRYVN-G----KLVESLQSRLVEYLLPRSILTFSYELIHRIVMGEVPPALKPNHRILMANPVVSNEFLDHIRAG 289
                 ***************************765.3....456666666778889*****99999877777788889************************** PP

    FMO-like 295 avk.vkssvkeltetsaifedgtveedidvvifatGytfafpfleeslvk.veknkvslykkvfpanlekptlaiiGliqplGsilptvelqarwavrv 391
                  +   ++sv+ + e+++++ +g + e +d vif+tGy  ++p + e   +  ++n v ly+ v  ++ e  tl  +Gl++ lG i ptvelqarwav  
  EEA22122.1 290 HIApHRASVESFAESAIVLSNGETLE-VDEVIFCTGYNVTMPVIAEETYRgEKQNSVHLYRLVNSPTYE--TLFFLGLVEFLGPIHPTVELQARWAVAS 385
                 9974689**************98875.9**************99766555167899*******999986..9*************************** PP

    FMO-like 392 lkGlkklpsekelleeitekkekkakrfgesksktiqtdyiayldelaaligakpnllslllk.....dpklalkv....ffGpcspyqyrlvGpGkwe 481
                 l G  +lps++++ +ei+++++++   f++s+++ti    + y + laa +g+kpn+  l+ k     +p   l +    + G  ++  yrl G G+ +
  EEA22122.1 386 LTGRIHLPSREKMQKEIKKAEKEQETNFVNSRRHTIAVPALGYQETLAADLGIKPNFRKLFQKyilsrNPADGLSIvnyyYNGMITSAPYRLFGHGNKP 484
                 ********************9999********************************9887654222236765544322224599999*******99876 PP

    FMO-like 482 Garkailtqwdr 493
                    +a + ++ r
  EEA22122.1 485 ELAEATILRMSR 496
                 655555555544 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.9   0.0   2.8e-18   3.9e-15       2     201 ..      13     220 ..      12     258 .. 0.80
   2 !   11.7   0.0     8e-05      0.11     212     305 .]     276     363 ..     264     363 .. 0.79
   3 ?   -1.0   0.0      0.62   8.5e+02     235     271 ..     399     442 ..     374     466 .. 0.63

  Alignments for each domain:
  == domain 1  score: 55.9 bits;  conditional E-value: 2.8e-18
  Pyr_redox_3   2 IiGaGPaGlaaaielkkagledylilEkgnignsiyrypkemtfispsftsekleipd.lnaiseets..pafslk.eeklsrkealeYlrevaksfe 95 
                  IiGaG  Gl aa e+ + gl   ++ E         +y +   +    f s   ++     a+  + s  p    +  ++++ k++l+Y  e+a +f 
   EEA22122.1  13 IIGAGISGLVAAKECLEEGLL-PTVYEARPYIGGQWHYEEPDSLTGETFSSVYDGVVSnTCALRSQFSdfPMDPAQyPDYPTHKDYLRYIHEYAGHFG 109
                  9*******************6.68***99666666678777666555544443333320222222233343333333679****************** PP

  Pyr_redox_3  96 lp..iklfeeVesvkkedegfevetsketyeAkkviiAtGefdkPnklnipGeek...lvkhyskvkefhkyagqkvvViGgknSavDaAlelvrkga 188
                  l+  i l++ V s +k++++ +v+t++ +     ++i tG+ + P+ + + G e+    ++h++ +++++ yag++v++iG + SavD+  e+ ++  
   EEA22122.1 110 LEkyILLNTGVISCDKQGHQWRVTTRTTEELFGALFICTGKESVPHIPAVTGLERfagRAIHSHIYRQPEVYAGKRVAIIGLGSSAVDISSEVSKHAE 207
                  *7779***********************99999*******************997556799************************************* PP

  Pyr_redox_3 189 eVtvvtrgseiek 201
                  + +++t++  +  
   EEA22122.1 208 SCHLITQRGGWVL 220
                  *****99988755 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 8e-05
  Pyr_redox_3 212 pdienrleelvkeekikvlfnaevkeikekeeeykvktedgkkvevkddvvlatGykpdlsflkkslfeldedgrpvlteeteetnvpglflaG 305
                  p++ n++ + ++ ++i  +   +v++  e+     +  ++g+++ev d+v+++tGy+ ++ +++++    ++++ ++l    ++ +++ lf+ G
   EEA22122.1 276 PVVSNEFLDHIRAGHIAPHRA-SVESFAES----AIVLSNGETLEV-DEVIFCTGYNVTMPVIAEETYRGEKQNSVHLYRLVNSPTYETLFFLG 363
                  666666666666665655544.56666653....566788899888.899***************99999999999999999999999999988 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 0.62
  Pyr_redox_3 235 vkeikekeeeykvktedgkkvev......kddvvla.tGykpdl 271
                   keik+ e+e + ++ + +++++      +++ ++a +G kp++
   EEA22122.1 399 QKEIKKAEKEQETNFVNSRRHTIavpalgYQETLAAdLGIKPNF 442
                  35666666666666666555444224444555555555555555 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.8   0.0   1.8e-12   2.5e-09       2     175 ..      10     216 ..       9     251 .. 0.73
   2 !    6.4   0.0    0.0032       4.4     201     243 ..     294     331 ..     258     353 .. 0.68

  Alignments for each domain:
  == domain 1  score: 36.8 bits;  conditional E-value: 1.8e-12
                  SEEEE--SHHHHHHHHHHHHHTS-EEEEE....TTHCHHHCSHHH......HCHHHHHHHHHHHHH................................ CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxx......xxxxxxxxxxxxxxx................................ RF
  Pyr_redox_2   2 dvvviGgGpAGlaaaltlaqagakvtlve....legtclnggcll......skallgvaedaeias................................ 57 
                  +v++iG+G+ Gl aa++  + g+  t++e     +g+++++ +        s+++ gv +                                      
   EEA22122.1  10 RVAIIGAGISGLVAAKECLEEGLLPTVYEarpyIGGQWHYEEPDSltgetfSSVYDGVVS-----Ntcalrsqfsdfpmdpaqypdypthkdylryih 102
                  79**************************88888666666665533333333444444444.....13444577788888888899*********9999 PP

                  HHHHCHHHHCCCCHCCTCEEEEESCEEEEETEEECTCEEEEEESEEEE---EEE-BCTCTTC.TTBEECCSECHHHHHHCCSS-T.SEEEEES-SHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxx RF
  Pyr_redox_2  58 evvkklnqgielllgeevvkidpgkkkvklekkkegdeekiaydklvlAtGssprdlgipGvaenvgklvrtldsaealklkllp.krivvvGgGyiG 154
                  e    ++ +   ll++ v++ d++ ++  +++++    ++  +++l+++tG +   ++ip+v     +  r+++s  + + +    kr++++G G  +
   EEA22122.1 103 EYAGHFGLEKYILLNTGVISCDKQGHQWRVTTRT----TEELFGALFICTG-KESVPHIPAVTGLERFAGRAIHSHIYRQPEVYAgKRVAIIGLGSSA 195
                  44444555533444457*****999999997665....4669*********.5555666666555555568888887777777778************ PP

                  HHHHHHHHHHT-EEEEEESSS CS
                  xxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 155 vElAaalaklgkevtlveard 175
                  v+++++ +k ++  +l+ +r 
   EEA22122.1 196 VDISSEVSKHAESCHLITQRG 216
                  ************998887654 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.0032
                  EESCEEEEEEETTEEEEEEETTSCEEEESEEEE-S-EEES-HH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 201 klgtsvkeidgngeklevvledgeeidadlvvvavGvrpstel 243
                  + ++sv+ + +       vl++ge++++d v++++G+    + 
   EEA22122.1 294 H-RASVESFAESA----IVLSNGETLEVDEVIFCTGYNVTMPV 331
                  4.56665555444....57888888888888888887765544 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0     0.062        85     190     213 ..       7      30 ..       3      43 .. 0.85
   2 !   26.4   0.0   2.5e-09   3.5e-06      91     221 ..      90     211 ..      74     223 .. 0.76
   3 ?    1.8   0.0     0.074     1e+02     326     341 ..     311     326 ..     300     327 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.062
  K_oxygenase 190 akkriaVvGsGqSaaeifedllrr 213
                  + +r+a++G+G S+   ++++l++
   EEA22122.1   7 QVERVAIIGAGISGLVAAKECLEE 30 
                  5689*********99888888876 PP

  == domain 2  score: 26.4 bits;  conditional E-value: 2.5e-09
  K_oxygenase  91 flpsRkefedYlrWvasqle..eqvrfgeeveevepdeeeeeelltveskdaegeeeelearnlvlgvGtepkiPevleklegkervvHsseylerke 186
                  ++p+ k++ +Y+++ a ++   + +  ++ v + + +     + ++v+++    +ee + a  ++ g  + p+iP+v+   +   r +Hs+ y + + 
   EEA22122.1  90 DYPTHKDYLRYIHEYAGHFGleKYILLNTGVISCDKQG----HQWRVTTR---TTEELFGALFICTGKESVPHIPAVTGLERFAGRAIHSHIYRQPE- 179
                  5899999***********98313344444444433333....46899983...355667776677777799*****977666679******998876. PP

  K_oxygenase 187 ellakkriaVvGsGqSaaeifedllrrqkkvelkl 221
                     a+kr+a++G G Sa +i  ++ ++++  + +l
   EEA22122.1 180 -VYAGKRVAIIGLGSSAVDISSEVSKHAE--SCHL 211
                  .9*******************99988876..4444 PP

  == domain 3  score: 1.8 bits;  conditional E-value: 0.074
  K_oxygenase 326 eetlevdavvlATGYr 341
                   etlevd v+++TGY+
   EEA22122.1 311 GETLEVDEVIFCTGYN 326
                  6899***********7 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.3   0.0   6.2e-11   8.6e-08       1      42 [.      13      54 ..      13      73 .. 0.88

  Alignments for each domain:
  == domain 1  score: 32.3 bits;  conditional E-value: 6.2e-11
                   EE--SHHHHHHHHHHHCCTEEEEEE-SSSSSSGGG-EECETT CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekrdrlGGraasyevpg 42
                   I+GaG+sGlvaA ++ ++g+  +++e+r+++GG+++ +e + 
     EEA22122.1 13 IIGAGISGLVAAKECLEEGLLPTVYEARPYIGGQWHYEEPDS 54
                   9**********************************9988754 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.0   2.4e-05     0.033       1     155 [.      12     150 ..      12     151 .. 0.82
   2 ?   -1.5   0.0       1.6   2.1e+03       1      20 [.     187     206 ..     187     213 .. 0.82
   3 !    7.4   0.0     0.003       4.1     123     155 ..     297     325 ..     279     326 .. 0.75

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 2.4e-05
  NAD_binding_9   1 aivGaGprGlavlerLlarakkkspleitlfdpsepgagrvwrtdqseelllNvpasemslftddpptfaeWlrergaleeaeeldpddfvpRaly 96 
                    ai+GaG++Gl ++++ l++      l  t+++ +++  g+ w+ ++++ l   + +s       ++  ++   ++ +    ++ ++  d+++ + y
     EEA22122.1  12 AIIGAGISGLVAAKECLEEG-----LLPTVYEARPYI-GGQWHYEEPDSLTGETFSSVYDGVVSNTCALRSQFSDFP----MDPAQYPDYPTHKDY 97 
                    8*****************95.....8889*******9.99999999***9999999999999888877777666666....356677788888888 PP

  NAD_binding_9  97 GrYlrdlfeellarlpegvtvevhraevvdleeradgqavlladgaslaadaVvLAlGh 155
                     rY+++++ ++   l++     ++++ v+++++++ +++v +++ ++  + a+++++G 
     EEA22122.1  98 LRYIHEYAGHFG--LEK---YILLNTGVISCDKQGHQWRV-TTRTTEELFGALFICTGK 150
                    888888888887..443...56889999999999998877.677777889999999996 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1.6
  NAD_binding_9   1 aivGaGprGlavlerLlara 20 
                    ai+G G +++ +  ++ ++a
     EEA22122.1 187 AIIGLGSSAVDISSEVSKHA 206
                    8********99988887775 PP

  == domain 3  score: 7.4 bits;  conditional E-value: 0.003
  NAD_binding_9 123 evvdleeradgqavlladgaslaadaVvLAlGh 155
                    +v++ +e     a++l++g++l++d+V+ ++G 
     EEA22122.1 297 SVESFAE----SAIVLSNGETLEVDEVIFCTGY 325
                    4444443....3689*****************6 PP

>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.0   3.8e-07   0.00053       1      80 [.      18      99 ..      18     121 .. 0.79
   2 ?   -1.3   0.0      0.71   9.8e+02     225     261 ..     114     150 ..     104     172 .. 0.87

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 3.8e-07
                   HHHHHHHHHHHHTTEEEEEEESSSSSBTTS-EEEETTEEEESS--EEET...TTHHHHHHHHHTTCCCCEEEESCCGCEEEEE CS
  Amino_oxidase  1 laGLaaArqLlsaGfdVtvlEardrvGGRirtvrsdGylielGamwftg...agnpllellkelgledslslpdpgapkrvls 80
                   ++GL+aA++ l+ G+  tv+Ear+ +GG  + ++ d+ + e+ ++++ g   +  +l   + ++ ++  + +pd+ + k++l 
     EEA22122.1 18 ISGLVAAKECLEEGLLPTVYEARPYIGGQWHYEEPDSLTGETFSSVYDGvvsNTCALRSQFSDFPMDPAQ-YPDYPTHKDYLR 99
                   8*********************************999999999999999883334444456667777666.466666666655 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.71
                    EETSEEEEEEEEETTCEEEEETTSTEEEESEEEE-S- CS
  Amino_oxidase 225 irlntrVkeikregdgvtvtledgevveaDaVvvTvp 261
                    i+lnt V + +++g+  +vt+++ e++ +   ++T  
     EEA22122.1 114 ILLNTGVISCDKQGHQWRVTTRTTEELFGALFICTGK 150
                    899*************************999999975 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.2   3.1e-06    0.0042       1      36 [.      10      46 ..      10      49 .. 0.93
   2 ?   -0.3   0.0      0.45   6.2e+02     144     204 ..      96     152 ..      86     186 .. 0.65
   3 ?   -0.4   0.0      0.49   6.7e+02     168     205 ..     297     328 ..     165     358 .. 0.72

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 3.1e-06
                EEEEECTSHHHHHHHHHHHHTT..EEEEESSSSTTSSG CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..Vtllekgdiagsga 36
                +v+iiG+Gi Gl +A e  ++g   t++e+++ +g g+
  EEA22122.1 10 RVAIIGAGISGLVAAKECLEEGllPTVYEARPYIG-GQ 46
                59*****************************9999.65 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.45
                 EHHHHHHHHHHHHHHTT-EEEESECEEEEEEEETCEEEEE.EECTEEEEEEEEEEE--GGGH CS
         DAO 144 dpakltaalaraaealGveilegtevtgleeedgkvwgve.rttpgendaadavVnaaGaws 204
                 d+ ++++ +a  +  l   il++t v + ++ +g  w+v  rtt++    + a+ +++G  s
  EEA22122.1  96 DYLRYIHEYAGHFG-LEKYILLNTGVISCDK-QGHQWRVTtRTTEEL---FGALFICTGKES 152
                 55566666666652.2224888899999965.467799955444333...588999999665 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 0.49
                 CEEEEEEEETCEEEEEEECTEEEEEEEEEEE--GGGHH CS
         DAO 168 evtgleeedgkvwgverttpgendaadavVnaaGawsd 205
                  v+++ e     + v   ++ge+ ++d v+ ++G  ++
  EEA22122.1 297 SVESFAE----SAIV--LSNGETLEVDEVIFCTGYNVT 328
                 3444422....1222..333555356889999987754 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.0   0.00097       1.3       1      35 [.      10      44 ..      10      51 .. 0.91
   2 !    8.5   0.0    0.0021       2.9       1      50 [.     185     236 ..     185     247 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00097
                EEEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSS CS
   Pyr_redox  1 kvvvvGgGyiglElAgalaelgkkVtvversdkll 35
                +v+++G+G +gl +A++  e g   tv e+++ + 
  EEA22122.1 10 RVAIIGAGISGLVAAKECLEEGLLPTVYEARPYIG 44
                79********************9999999998876 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0021
                 EEEEECSSHHHHHHHHHHHHTTSEEEEEESS.SSSS.TTSSHHHHHHHHHHH CS
   Pyr_redox   1 kvvvvGgGyiglElAgalaelgkkVtvvers.dkll.rllDeeaskilqekl 50 
                 +v+++G G ++++  ++ ++++ + +++  +  ++l r+ + ++ + lq +l
  EEA22122.1 185 RVAIIGLGSSAVDISSEVSKHAESCHLITQRgGWVLpRYVNGKLVESLQSRL 236
                 79***********************999765155556666555555555544 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   3.4e-06    0.0048       2      39 ..      11      48 ..      10      50 .. 0.92

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 3.4e-06
                   EEEE--SHHHHHHHHHHHHTTT-EEEEESSSGGGSGGG CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGlkvavvekeqefggata 39
                   v +iG+G++GL+AA e+ e+Gl  +v e  ++ gg+ +
     EEA22122.1 11 VAIIGAGISGLVAAKECLEEGLLPTVYEARPYIGGQWH 48
                   89********************9999999999999876 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   8.1e-05      0.11       2      36 ..      10      44 ..       9      47 .. 0.90
   2 ?   -0.7   0.0      0.31   4.3e+02     128     173 ..     116     159 ..     111     178 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 8.1e-05
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SSSSS- CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVlllekakklg 36
                 +v++iG+G +Gl aA ++ ++g   +++e+ + +g
   EEA22122.1 10 RVAIIGAGISGLVAAKECLEEGLLPTVYEARPYIG 44
                 69********************9999999887766 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.31
                  -S--EEEEECETTE.EEEEE.TTEEEEESEEEE----SS-GGGT-- CS
  HI0933_like 128 letevksvekeedgkfrvktkseeeleadklvlAtGGlSiPklGst 173
                  l+t v s +k ++++ rv+t+++eel   +l + tG +S+P++ + 
   EEA22122.1 116 LNTGVISCDK-QGHQWRVTTRTTEEL-FGALFICTGKESVPHIPAV 159
                  5666777766.455599999555555.56788889******98665 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00026      0.36      15      55 ..       6      45 ..       4      61 .. 0.88
   2 ?    0.8   0.0      0.17   2.3e+02       2      39 ..     168     205 ..     167     215 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00026
                HTEEEEEEE--SHHHHHHHHHHHHCTTS-EEEEESSSS--T CS
        Thi4 15 yaesDvvivGaGssGLtaayylakkpdlkvailersvspGG 55
                + +  v+i+GaG sGL aa+   ++ +l  ++ e++  +GG
  EEA22122.1  6 FQVERVAIIGAGISGLVAAKECLEE-GLLPTVYEARPYIGG 45
                667789***************9999.999999999987776 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.17
                 HHHHHHHHHHHHHHTEEEEEEE--SHHHHHHHHHHHHC CS
        Thi4   2 raiveryfedllkyaesDvvivGaGssGLtaayylakk 39 
                 rai ++ +++   ya   v+i+G Gss +  +  ++k+
  EEA22122.1 168 RAIHSHIYRQPEVYAGKRVAIIGLGSSAVDISSEVSKH 205
                 77888888888899*************99999888887 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   3.7e-05     0.051       2      38 ..      11      47 ..      10     146 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 3.7e-05
  FAD_oxidored  2 vvVvGGgpaGvaAAiaAaraGakvlLveergvlGGll 38
                  v ++G+g++G++AA  + ++G    + e r+++GG+ 
    EEA22122.1 11 VAIIGAGISGLVAAKECLEEGLLPTVYEARPYIGGQW 47
                  89*********************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (520 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       633  (0.0353059); expected 358.6 (0.02)
Passed bias filter:                      598  (0.0333538); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.66u 0.29s 00:00:00.95 Elapsed: 00:00:00.44
# Mc/sec: 3574.21
//
Query:       EEA22123.1  [L=541]
Description: pantothenate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-33  116.5  23.7    1.2e-33  116.5  23.7    2.0  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
        2.2    8.6   7.8        1.7    9.0   1.6    3.3  3  DUF1772   Domain of unknown function (DUF1772)
        7.7    7.0   6.5       0.61   10.5   0.2    2.2  2  DUF2681   Protein of unknown function (DUF2681)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.5  23.7     2e-37   1.2e-33       2     347 ..      73     436 ..      72     442 .. 0.86
   2 !    2.9   0.5    0.0071        42      18      58 ..     440     482 ..     435     488 .. 0.54

  Alignments for each domain:
  == domain 1  score: 116.5 bits;  conditional E-value: 2e-37
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgag 100
                  +++f+  l++++++ a+ + ++edl+++++ ++ll t++ +g++++++p   + +r+ +  +l ++ ll+++ +++++ a+++  +++lr+++G+ ++
  EEA22123.1  73 TIGYFVRLLDSANVINAYVSGMKEDLNFTGADYNLLSTFFIIGYVIGQVPSQMILTRVRPSYWLPTCELLWSIVTFCFAAAQNVRDVFALRIVMGFLEA 171
                 589**********9999999**************************************5555************4444434776689************ PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg.......Wravfyilaivsllafvlfllllpeepperkrkspkeee.... 188
                  ++ ++++++  w++++e ++ i++++++  +++++   l + ++           Wr++f++++++sl + + +++ +p++p ++k +   +      
  EEA22123.1 172 PFAVGVLTIMGSWYTPRELSKRIAIFYSACYAASMFSGYLQAGIYRGMDdhlglpgWRWLFIFCGVISLPFSLYGYIAIPDNPYNSKAFWMPPHQlefa 270
                 ******************************************88844447888999******************9999988888888886666656666 PP

       MFS_1 189 .....kgtgpaplvpawkallkdpvlw...illialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrlsdrlgrrrrlll 279
                      + + + p+   w ++++    w   ++ +++++  + +++ l ++ ++l++ + +s ++++ +++ ++++vg+i  l  ++l+d +g ++r+  
  EEA22123.1 271 rkrmeACDRRPPVMLTWAKMRRIVTHWplyAFTAIMIC-QCLVTQPLNYFAVWLKSLHRFS-VYQVNVIPTAGQAVGLITTLTYSWLADAWGGEKRWKA 367
                 66666455555555556666666655653133333333.334445888888889*******.9************************************ PP

       MFS_1 280 allllllaalglallavtssavllllvlvliGfglgfvfpsllalasdla..ppeeagtasglfntagsl 347
                  l+ +++ ++gl++++      ++l++++l G  +gf +p+ +a++++++   pee++ ++g+++t+g++
  EEA22123.1 368 LLIPAVVNLVGLIIVSIGPGFGATLFGYLLNGASWGF-WPICFAWTNEVCasDPEERAIVIGVAQTMGQA 436
                 ******************9999999999999999997.9*********999988************9985 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.0071
       MFS_1  18 alpl.alaedlgispseigl.lltlyalgaavaslplGrlsdr 58 
                 ++p+ +l+++  + + ++g+ +lt++++ ++++++++ ++++r
  EEA22123.1 440 WVPIlILNTSKYAPKFTMGWsILTGFSACQLAMVFVIRWFVQR 482
                 4444444444444555566666666666666666666666665 PP

>> DUF1772  Domain of unknown function (DUF1772)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.7      0.28   1.7e+03      47      82 ..     199     244 ..     133     307 .. 0.58
   2 ?    9.0   1.6   0.00028       1.7      32      79 ..     329     382 ..     299     385 .. 0.71
   3 ?    0.8   0.0     0.096   5.8e+02      58     108 ..     454     499 ..     402     508 .. 0.58

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.28
     DUF1772  47 alafayla...............araasrgarllylaaaallllsivpyTl 82 
                 ++++a ++                +   +g r+l+ + +++++   +p++l
  EEA22123.1 199 SACYA-ASmfsgylqagiyrgmdDHLGLPGWRWLF-IFCGVIS---LPFSL 244
                 33333.11223444456666653222223323333.3344333...34333 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00028
     DUF1772  32 fkrg.kavfpp....lallsalafaylaaraasrgarllylaaaal.lllsivp 79 
                 f+++   v+p+    ++l+++l + +la  + ++++++ +l+ a++ l+  i++
  EEA22123.1 329 FSVYqVNVIPTagqaVGLITTLTYSWLADAWGGEKRWKALLIPAVVnLVGLIIV 382
                 44444557777899899***********************99999977655543 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.096
     DUF1772  58 asrgarllylaaaal.lllsivpyTllvmvPtNnkLaalk.eedakekedeae 108
                 + +  + ++++ +a+ l+  +v++   ++    ++    +  e+++++++e+e
  EEA22123.1 454 KFTMGWSILTGFSACqLA--MVFVIRWFV-QRDKR----RaREQQQQQQEEEE 499
                 444456666666677444..444333333.33333....11233344444444 PP

>> DUF2681  Protein of unknown function (DUF2681)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   1.8      0.95   5.7e+03      37      51 ..      12      26 ..       6      30 .. 0.72
   2 ?   10.5   0.2    0.0001      0.61       5      41 ..     460     496 ..     456     502 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 0.95
     DUF2681 37 aekqqlkvekavaea 51
                ++ qq+++e++ a a
  EEA22123.1 12 QQPQQQQQEQRPASA 26
                667788888776665 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.0001
     DUF2681   5 allvgliaavlllvaylswqlkkarkknaklqaekqq 41 
                 ++l g++a  l++v+ + w +++ ++++++ q+++q 
  EEA22123.1 460 SILTGFSACQLAMVFVIRWFVQRDKRRAREQQQQQQE 496
                 68899****************9998888777666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (541 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       890  (0.0496402); expected 358.6 (0.02)
Passed bias filter:                      507  (0.0282782); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.64u 0.29s 00:00:00.93 Elapsed: 00:00:00.45
# Mc/sec: 3591.06
//
Query:       EEA22124.1  [L=255]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (255 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1285  (0.0716716); expected 358.6 (0.02)
Passed bias filter:                      746  (0.0416086); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 1719.76
//
Query:       EEA22125.1  [L=726]
Description: oligopeptidase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.5e-48  163.5   0.1    1.5e-47  161.8   0.1    1.8  2  Peptidase_S9  Prolyl oligopeptidase family
     0.0022   16.7   0.0        0.4    9.3   0.0    2.1  2  AXE1          Acetyl xylan esterase (AXE1)
  ------ inclusion threshold ------
      0.025   14.5   0.0       0.91    9.5   0.0    2.9  2  PD40          WD40-like Beta Propeller Repeat


Domain annotation for each model (and alignments):
>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0      0.26   1.5e+03      93     135 ..     146     185 ..     128     216 .. 0.65
   2 !  161.8   0.1   2.6e-51   1.5e-47       1     210 [.     489     698 ..     489     699 .. 0.95

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.26
                   EEESE---CCCHHCSTTSTHHHCCCC--TTTCHHHHHHHHHH- CS
  Peptidase_S9  93 vaevpvvdvlrydsdtdllteeymewgnpeeneegykelspys 135
                    a+ p +  ++y s+   + ++++e+ +p++n   y  l++  
    EEA22125.1 146 DAKKPLSSGRYYTST---WVRHWDEYIEPQKNSLWYGVLQNSP 185
                   566777777777777...9999999999988877776555544 PP

  == domain 2  score: 161.8 bits;  conditional E-value: 2.6e-51
                   ----HHHHHHHCCT-EEEEE--TTSSTTHCHHHHTTSGGGGHHHHHHHHHHHHHHHHTT.S--GGGEEEEEETHHHHHHHHHHH.H-GGG-SEEEEE CS
  Peptidase_S9   1 psfsselqlladrGyvvvvanirGsggyGeafhdagkrklgqnefdDfiaaaealakeg.yvdserlaitGgSyGGyltgaaln.qrpdlFkaavae 95 
                   +s++++++++a++Gyvvv +n++Gs+gyG++f+da+ + +g   + D+  + +++ k+  yvd++r ++ G+SyGGy+++++++   +++Fka+v +
    EEA22125.1 489 WSTRWNPAVFAEQGYVVVTPNPTGSTGYGQDFTDAIIGSWGGLPYLDLERGFDYISKNLtYVDTDRAVALGASYGGYMMNWIQGqPLGRKFKALVTH 585
                   7889********************************************************************************7789********* PP

                   SE---CCCHHCSTTSTHHHCCCC--TTTCHHHHHHHHHH-CGGG-----EEEEEEETT-SSS-THHHHHHHHHHH--S-SEEEEEETTS-SSTTSSH CS
  Peptidase_S9  96 vpvvdvlrydsdtdllteeymewgnpeeneegykelspyspldnvkaypplLlihGlaDdrvppaealklvaaLqkkgknvlllifpdegHgvgkpr 192
                   ++v+ ++++  +++ + +  +  g  ++ +e+ +++ p + ++n  + +p L+ih ++D+r ++ae+l  ++ Lq kg ++ +l+fpde+H+v +p+
    EEA22125.1 586 DGVFSMVSQLASEEQYFPLADLKGPLWKVPEEWQKWDPSRFTAN--WATPHLIIHNELDYRLTIAEGLAAFNVLQMKGIDSAFLTFPDENHWVLQPE 680
                   ************99955545555666899999************..*************************************************** PP

                   HHHHHHHHHHHHHHHHCT CS
  Peptidase_S9 193 akveelarllaFlkealg 210
                   ++  ++  + +++++++g
    EEA22125.1 681 NSLVWHYAVINWINKYVG 698
                   **************9976 PP

>> AXE1  Acetyl xylan esterase (AXE1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.0   6.6e-05       0.4      51     127 ..     437     520 ..     423     530 .. 0.77
   2 !    5.2   0.0    0.0012       7.1     155     187 ..     533     566 ..     532     602 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 6.6e-05
                 -SSEEEEEEEEEEGGGEEEEEEEEEES...SSSSEEEEEEEE-TT--GGG..HH...HHHHHHHTT-EEEEEE-TTTS..SSB- CS
        AXE1  51 lkavkvydltfegvrgarikaklvlPke..keeklPavvefhGYegsrge..ih...dllnyaaaGyavvvmdvRGqggesedk 127
                 l+  +v ++ ++g ++++i+a +v+P++   +ek P+ +  hG  +s+++  ++   +   +a +Gy+vv+ +  G  g+ +d 
  EEA22125.1 437 LSRSQVDEIWYKGENDQPIHAFVVKPSNfnPDEKYPLAFLVHGGPESAWNdsWStrwNPAVFAEQGYVVVTPNPTGSTGYGQDF 520
                 566778899*****************9622579*******9*988775541144112345689999999999999999998884 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0012
                 HHHHHHHHHHH.HTSTTEEEEEEEEEEETHHHHH CS
        AXE1 155 flDavrlveiv.aslpevDeeRvavlGasqGGal 187
                 +lD  r  + + ++l  vD +R ++lGas GG +
  EEA22125.1 533 YLDLERGFDYIsKNLTYVDTDRAVALGASYGGYM 566
                 677777776542799*****************76 PP

>> PD40  WD40-like Beta Propeller Repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.0   0.00015      0.91       9      30 ..     277     298 ..     276     311 .. 0.78
   2 ?    1.5   0.0     0.052   3.1e+02      14      32 ..     339     356 ..     337     361 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00015
                 S.EEEEEE-TTSSEEEEEEECT CS
        PD40   9 gnegaPsfSPDGkrlaFsSdRg 30 
                 g + +P++S+DG+ ++F  + +
  EEA22125.1 277 GAMSSPALSNDGSAIVFLAQEK 298
                 56789************98876 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.052
                 EEE-TTSSEEEEEEECT.T CS
        PD40  14 PsfSPDGkrlaFsSdRgsG 32 
                  s+ +D k+l ++ + + G
  EEA22125.1 339 VSWAKDNKSLLITVEEQ-G 356
                 59*********998887.5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (726 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       299  (0.0166769); expected 358.6 (0.02)
Passed bias filter:                      276  (0.0153941); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.68u 0.28s 00:00:00.96 Elapsed: 00:00:00.51
# Mc/sec: 4297.93
//
Query:       EEA22126.1  [L=2208]
Description: pre-mRNA splicing helicase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   6.1e-165  546.6   0.1    5.4e-93  310.9   0.0    2.2  2  Sec63          Sec63 Brl domain
    7.2e-50  169.2   0.1    2.5e-28   99.0   0.0    3.1  3  DEAD           DEAD/DEAH box helicase
    1.3e-28   99.3   0.5    3.8e-28   97.9   0.5    1.8  1  Helicase_PWI   N-terminal helicase PWI domain
    3.5e-23   82.5   0.0    5.8e-13   49.2   0.0    2.5  2  ResIII         Type III restriction enzyme, res subunit
    2.4e-11   44.0   0.0    7.7e-08   32.7   0.0    3.7  2  Helicase_C     Helicase conserved C-terminal domain
    1.6e-06   28.5   0.9      0.017   15.4   0.1    3.8  3  AAA_22         AAA domain
    1.4e-05   24.9   0.0     0.0024   17.6   0.0    2.5  2  AAA_30         AAA domain
    0.00092   19.6   0.0        1.4    9.3   0.0    3.2  2  AAA_16         AAA ATPase domain
     0.0021   17.5   0.0       0.16   11.4   0.0    2.6  2  PhoH           PhoH-like protein
     0.0046   17.3   0.0        3.5    7.9   0.0    2.8  2  AAA_19         AAA domain
  ------ inclusion threshold ------
      0.019   14.5   0.0        1.5    8.2   0.0    2.6  2  UvrD-helicase  UvrD/REP helicase N-terminal domain
      0.047   12.8   0.0        1.1    8.3   0.0    2.3  2  T2SSE          Type II/IV secretion system protein


Domain annotation for each model (and alignments):
>> Sec63  Sec63 Brl domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  310.9   0.0   3.6e-96   5.4e-93       1     257 []    1032    1339 ..    1032    1339 .. 0.98
   2 !  233.7   0.2   1.3e-72   1.9e-69       1     256 [.    1868    2188 ..    1868    2189 .. 0.96

  Alignments for each domain:
  == domain 1  score: 310.9 bits;  conditional E-value: 3.6e-96
                  ECHHHHHHHHHT--HHHHHHHHHHS-TT--HHHHHHHHHTSGGGGGS---TTHHHHHHHHHHTSSS--SSSTTSHHHHHHHHHHHHHTT---SSHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       Sec63    1 ptelGriaShYyisyetiklfneslkpnttlkdlLeilssasEFeeipvReeEkkelkkLlekvpikvkediespeaKvniLlqayisrlklegsdl 97  
                  +telGriaShYyis+++++++n +l+p  ++ +l++++s ++EF++ipvR++Ek el+kLl +vp++vke ie+p+aK+n+Llqayisrlkleg +l
  EEA22126.1 1032 STELGRIASHYYISHSSMQTYNLHLQPGISTVELFRVFSLSEEFKYIPVRQDEKLELAKLLGRVPVPVKEGIEEPHAKINVLLQAYISRLKLEGLAL 1128
                  69*********************************************************************************************** PP

                  HHHHHHHHHHHHHHHHHHHHHHHHTTBHHHHHHHHHHHHHHHHTS-TT................................................. CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................................................. RF
       Sec63   98 vsDlkyilqnairilralveillskgwlslalslleLskmveqrlwds................................................. 145 
                  ++Dl+y++q+a+rilra++ei+l+kgw+s+a+ +l+L+km e+r+w++                                                 
  EEA22126.1 1129 MADLVYVTQSAGRILRAIFEICLKKGWSSVAKVALNLCKMAEKRMWPTmtplrqfptcprdimqkaeridapwssyfdldpprmgellgmpkagriv 1225
                  ************************************************************************************************* PP

                  ......S--EEEEEEECEBTTSEEEEEEEEEESSSS-SCTSSS-CH..TSBEEEEEEEEETTTTEEEEEEEEEESSTTTTT.EEEEEEEEEEE-.SS CS
                  ......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxx RF
       Sec63  146 ......lPkleieaevqpitrsklrvevtiereeeeskpdfpwdkk..gksekfwlvvedsendellaikrvtlekkklas.tqevkleftvplsep 233 
                        +P+le++a+vqp trs lrve+ti+       p+f+wd+   g++e+fw+++ed++++e+l+++ ++l+k+  ++  + + +eftvp+s+p
  EEA22126.1 1226 cdlvskFPRLEVQAQVQPMTRSLLRVELTIT-------PNFVWDDAlhGTAESFWVIIEDCDGEEILFHDLFILRKEFAQGeVTDHIMEFTVPISDP 1315
                  *******************************.......************************************8775555889999********** PP

                  CCEEEEEEEEESSSSS-EEEEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxx RF
       Sec63  234 gpkqltvrlisdswlgldqevtis 257 
                   p++++++++sd+w+++d++v+is
  EEA22126.1 1316 IPPHYFLHIVSDRWMHSDTKVAIS 1339
                  ********************9986 PP

  == domain 2  score: 233.7 bits;  conditional E-value: 1.3e-72
                  ECHHHHHHHHHT--HHHHHHHHHHS-TT--HHHHHHHHHTSGGGGGS---TTHHHHHHHHHHTSSS--S.SSTTSHHHHHHHHHHHHHTT---SSHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       Sec63    1 ptelGriaShYyisyetiklfneslkpnttlkdlLeilssasEFeeipvReeEkkelkkLlekvpikvk.ediespeaKvniLlqayisrlklegsd 96  
                  p ++++ia++Y+is+ t+++f  sl+++t+lk++Lei++sa+EFe+i++R++E+++l++++++vp+k++ ++++sp++K+++Llqa++sr++l+  d
  EEA22126.1 1868 PMNAAMIAAYYNISFITMQTFLLSLSARTKLKGILEIITSATEFESIQMRRHEDHILRRVYDRVPVKMAePAYDSPHFKAFVLLQAHFSRMQLP-ID 1963
                  6789****************************************************************88************************.** PP

                  HHHHHHHHHHHHHHHHHHHHHHHHHTTBHHHHHHHHHHHHHHHHTS-TT................................................ CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx................................................ RF
       Sec63   97 lvsDlkyilqnairilralveillskgwlslalslleLskmveqrlwds................................................ 145 
                  l++D++ i+ ++ ++l+a+v++l+s+g+l++ ++++e+s+m +q++wd+                                                
  EEA22126.1 1964 LAKDQEVIVGKVLNLLSACVDVLSSEGHLNA-MNAMEMSQMTVQAMWDRdsplkqiphftteviqvanefnindifefmeamdpsenkdyatfvkrl 2059
                  ******************************9.***************999*********************************************** PP

                  .................S--EEEEEEE....CEBTTSEEEEEEEEEESSS..S-S......CTSSS-CHTSBEEEEEEEEETTTTEEEEEEEEEESS CS
                  .................xxxxxxxxxx....xxxxxxxxxxxxxxxxxxx..xxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       Sec63  146 .................lPkleieaev....qpitrsklrvevtiereee..esk......pdfpwdkkgksekfwlvvedsendellaikrvtlek 213 
                                   +P++e+++ev    ++++ ++  +++++er+ e  e        p +p +k    e++wlvv+++++++llaikrvt+ +
  EEA22126.1 2060 gldtkqlsqaanftndkYPNVEMDFEVedpdSITAGDPAYLKIKVERDIEdeE-PdttvhaPYYPGKK---MENWWLVVGEEKTKSLLAIKRVTIGR 2152
                  ******************************9999999999******9999641.25668889999999...************************88 PP

                  TTTTTEEEEEEEEEEE-.SSCCEEEEEEEEESSSSS-EEEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       Sec63  214 kklastqevkleftvplsepgpkqltvrlisdswlgldqevti 256 
                       + e++le  vp+   g+++lt++l+sds++g+dq  t+
  EEA22126.1 2153 -----RLETRLEYIVPT--AGEHELTLYLMSDSYVGVDQAPTF 2188
                  .....58899**99965..779*****************8877 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.0   0.0   1.7e-31   2.5e-28       2     172 ..     533     708 ..     532     714 .. 0.84
   2 ?   -1.6   0.0       1.3   1.9e+03     155     170 ..     855     868 ..     845     871 .. 0.76
   3 !   66.2   0.0     2e-21     3e-18       2     166 ..    1383    1545 ..    1382    1553 .. 0.86

  Alignments for each domain:
  == domain 1  score: 99.0 bits;  conditional E-value: 1.7e-31
                 HHHHHHHHHHH.TTCEEEEEESTTSSHHHHHHHHHHHHHHHS.......TTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHH CS
                 xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   2 diQaeaiplil.gggdvlvaaeTGsGKTlaflipvlqivyet.......kgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqls 92 
                 +iQ +++p++  ++g++lv+a+TGsGKT ++++ +l+++ ++          +  k+++++P+++L+++++ n+ k+++++++rv+ ++g+ +    ++
  EEA22126.1 533 RIQTKCYPTAFhDDGNMLVCAPTGSGKTNVAMLTMLREIGKNrnpntgeIMLDDFKIVYIAPLKALVQEQVGNFGKRLQPYGIRVSELTGDRQL--TKQ 629
                 79******9996778************************8876555554345559******************************977775444..555 PP

                 HHHTTCSEEEEEHHHHHHHH..HCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHH CS
                 xxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  93 kldngvdivvgtpgrlddll..stgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlpkd 172
                 ++ ++++i+v+tp+++d ++   t +  ++ vr+l++DE++ l d+ +++ +++i++++ +++++  +  +++ lSATlp +
  EEA22126.1 630 QI-ADTQIIVTTPEKWDVITrkATDSSYTKLVRLLIIDEIHLLHDD-RGPVLEAIVSRTLRQNETSDEPTRIVGLSATLP-N 708
                 66.789***********988754444559999*************8.*********999877777777788********9.3 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 1.3
                 TSTTTSEEEEEESSBS CS
                 xxxxxxxxxxxxxxxx RF
        DEAD 155 dgklqrqvivlSATlp 170
                 dg+   qv+v++ATl 
  EEA22126.1 855 DGS--IQVLVCTATLA 868
                 444..67*******95 PP

  == domain 3  score: 66.2 bits;  conditional E-value: 2e-21
                  HHHHHHHHHHH.TTCEEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTST.SEEEEEETTSSHHHHHHHHHT CS
                  xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxx RF
        DEAD    2 diQaeaiplil.gggdvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyid.lrvlliiggvaardqlskldn 96  
                  +iQ++a++ +  +++ v++aa+ GsGKT ++ +++l++ +   ++++ +a++++P +eL+   +n+++k+++ i   ++ + ++g+++  +l+ l  
  EEA22126.1 1383 RIQSQAFKSLFeSDEAVFLAAPAGSGKTVCAELALLRHWS---QSDKGRAVYIAPFQELIDSRYNDWSKRLSSIAgGKTIVKLTGETT-ADLKLL-D 1474
                  79******99956679********************9995...68888************************9654566655666554.688888.8 PP

                  TCSEEEEEHHHHHHHH..HCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEE CS
                  xxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   97 gvdivvgtpgrlddll..stgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlS 166 
                  ++d+v++tp ++d l   ++++ n++ v +++ DE +++     + +++ i+++++ i+ + +++ ++i lS
  EEA22126.1 1475 SADLVLATPVQWDVLSrqWQRRKNVQTVGLFIADELHMIGGY-LGYTYEIIVSRMQFIKLQIESDMRIIGLS 1545
                  9************98898455569****************98.88888889999998999888888888887 PP

>> Helicase_PWI  N-terminal helicase PWI domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.9   0.5   2.6e-31   3.8e-28       2     111 .]     295     409 ..     294     409 .. 0.93

  Alignments for each domain:
  == domain 1  score: 97.9 bits;  conditional E-value: 2.6e-31
  Helicase_PWI   2 kdelsvkeidafWLqrelkkiykDaeeaqelaeevleiLkseade.....lrelEnkLvelldydkfdliklllknrekivyctklaq.aqseeekq 92 
                   k+ ++++eida+WLqr++++i++D++ea+  a+++leiL+ +  +     lr++En+L+el+dy++ +l+ ++++n+++iv++tk+++ a++++ + 
    EEA22126.1 295 KEIIPAREIDAYWLQRQISTIFPDEHEATASARSALEILSGKDADgnerqLRDIENDLMELFDYEHPELVATFVRNKDRIVWVTKWRRlAENDDARL 391
                   67899***********************************9833345567*************************************999******* PP

  Helicase_PWI  93 eieeemkekpeleeileel 111
                    +e+em e  + ++il+e+
    EEA22126.1 392 LVENEMVEA-GHRDILDEI 409
                   *********.******986 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.2   0.0   3.9e-16   5.8e-13      22     170 ..     544     707 ..     525     708 .. 0.83
   2 !   30.6   0.0     2e-10     3e-07       8     150 ..    1377    1521 ..    1370    1545 .. 0.77

  Alignments for each domain:
  == domain 1  score: 49.2 bits;  conditional E-value: 3.9e-16
                 .TTSEEEEEESTTSTHHHHHHHHHHHH-S...............-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--.......-SEEEEE CS
      ResIII  22 krdkrglikmaTGtGKTlvaaklierllkkgkee..........kflflvprkslleqtleefkkflseaykeigkkvsgdkkkakekdstnkkilvtt 110
                 ++d ++l+ ++TG+GKT va+ ++ r   k+++           k++ ++p k+l++    +f k l+++      +++gd++   ++++ +++i+vtt
  EEA22126.1 544 HDDGNMLVCAPTGSGKTNVAMLTMLREIGKNRNPntgeimlddfKIVYIAPLKALVQEQVGNFGKRLQPYG-IRVSELTGDRQLT-KQQIADTQIIVTT 640
                 677799999***********999998888877778********************************9985.5778888998888.8************ PP

                 HHHHHHTH........HHHTTT-SEEEEETGGGTTS......T.....TTHHHHHT---SEEEEEESS-S CS
      ResIII 111 iqsldadseeeeeeseellrdrfdviiiDEaHrlgak.....k.....swreilekfkeavllglTATpe 170
                  ++ d +    ++++++   +   ++iiDE H l+++     +     + r+   + ++  ++gl+AT++
  EEA22126.1 641 PEKWDVIT---RKATDSSYTKLVRLLIIDEIHLLHDDrgpvlEaivsrTLRQNETSDEPTRIVGLSATLP 707
                 ********...7788888888888************865444144444555545555779********86 PP

  == domain 2  score: 30.6 bits;  conditional E-value: 2e-10
                  HHHHHHHHT.........TTSEEEEEESTTSTHHHHH.HHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG.....GEEEESSS-B--... CS
      ResIII    8 Qeeaienll.eklks..krdkrglikmaTGtGKTlva.aklierllkkgkeekflflvprkslleqtleefkkflseayke.igkkvsgdkkkakek 99  
                   ++  +++  +++ks  + d+ ++++++ G+GKT++a ++l ++ +++ ++ +++ ++p ++l++  +++++k ls+ +   +  k++g++     k
  EEA22126.1 1377 NWQTFNRIQsQAFKSlfESDEAVFLAAPAGSGKTVCAeLALLRHWSQS-DKGRAVYIAPFQELIDSRYNDWSKRLSSIAGGkTIVKLTGETTAD-LK 1471
                  566777777434444779999****************77777777776.557*******************99999876445555566666666.78 PP

                  ....-SEEEEEHHHHHHTH........HHHTTT-SEEEEETGGGTTS.T..TT CS
      ResIII  100 dstnkkilvttiqsldadseeeeeeseellrdrfdviiiDEaHrlgakk..sw 150 
                    ++++++++t  + d  s   ++++ ++  ++  ++i DE H +g+    ++
  EEA22126.1 1472 LLDSADLVLATPVQWDVLS---RQWQRRKNVQTVGLFIADELHMIGGYLgyTY 1521
                  889****************...99*******************9988633333 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.7   0.0   5.1e-11   7.7e-08       7     109 ..     760     910 ..     754     912 .. 0.73
   2 ?    5.9   0.0     0.011        16      16     109 ..    1611    1748 ..    1598    1750 .. 0.63

  Alignments for each domain:
  == domain 1  score: 32.7 bits;  conditional E-value: 5.1e-11
                 HHH.HHHTTTTSEEEEEESSHHHHHH.HHHH...........................HHHT...........TSTEEEESTTSTHHHHHHHHHHHHTT CS
  Helicase_C   7 lel.lkleeeggkilifvntidrlek.vkll...........................lekk...........gikvavlhgelpqnereeileqfnkg 65 
                 ++  l+++++g+++lifv+++++  k ++++                              +            + + ++h+ l+ ++r+ + + f +g
  EEA22126.1 760 YNKvLENTAKGHQMLIFVHSRKETAKtARYIrdkavemetigqilrsdaasrailaeeA--EnvddaalkdimPYGFGIHHAGLSLEDRDSVASLFADG 856
                 44425889999**********96644455555555555555666666666666666440..144555555567899999******************** PP

                 SSSEEEESGGGTSSSTSTTESEEEESSSSSSH..........HHHHHHHTTSSS CS
  Helicase_C  66 esdvLiatdvaerGidipkvnlVinfdlprnv..........tsyiqriGRtgR 109
                 +++vL++t  ++ G+++p  +++i     +++          ++  q+ GR+gR
  EEA22126.1 857 SIQVLVCTATLAWGVNLPAHTVLIKGTQVYSPehgafvqlspQDTLQMLGRAGR 910
                 ******************777777555554444444555555************ PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.011
                  TSEEEEEESSHHHH...................HHHHHH...................HHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESG CS
  Helicase_C   16 ggkilifvntidrl...................ekvkll...................lekkgikvavlhgelpqnereeileqfnkgesdvLiatd 74  
                  ++ +l+fv++++++                        l                    e+ +  v ++h  l++++++ + + f  g ++v++a++
  EEA22126.1 1611 DKPVLVFVPSRKQVrstavdilaacaaddnedrF----LhadveqiapllerihertlAESISHGVGYYHEALSTSDKRIVSHLFTIGAIQVMLASR 1703
                  5566666666664422333333333333333220....033333333332332222214444899999***************************** PP

                  GGTSSSTSTTESEEEESSSS...........SSHHHHHHHHTTSSS CS
  Helicase_C   75 vaerGidipkvnlVinfdlp...........rnvtsyiqriGRtgR 109 
                  ++   id+  ++lVi ++ +           + ++++ q+ G + R
  EEA22126.1 1704 DVCWEIDF-TAHLVIVMGTQffegrehryidYPISEILQMFGKASR 1748
                  ********.59****9999866654443332224888888888777 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.1   1.1e-05     0.017       5     115 ..     546     685 ..     543     701 .. 0.63
   2 ?   -1.4   0.0       1.7   2.6e+03      79     112 ..     797     829 ..     752     832 .. 0.73
   3 !    8.6   0.0    0.0015       2.2       7     103 ..    1398    1513 ..    1394    1542 .. 0.61

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 1.1e-05
      AAA_22   5 agilvvtGesGtGKTtllrrlleqldeeakaee......erpevvfvtlpsst.....sskdllrellralglelka...................... 70 
                 +g ++v++++G+GKT ++   + + ++ ++ +                    +      +k l +e + ++g +l                        
  EEA22126.1 546 DGNMLVCAPTGSGKTNVAMLTMLR-EIGKNRNPntgeimL---------DDFKivyiaPLKALVQEQVGNFGKRLQPygirvseltgdrqltkqqiadt 634
                 7889***********887555554.344444334556652.........33333333334445555555555555555566666777766667766666 PP

      AAA_22  71 .....erlsseellealeqalraravielliiDEaqhlr..seealeeLrsl 115
                       + + + + ++ ++ + ++ v +lliiDE++ l   +  +le ++s+
  EEA22126.1 635 qiivtTPEKWDVITRKATDSSYTKLV-RLLIIDEIHLLHddRGPVLEAIVSR 685
                 66663355555555888888888888.***********66559999988443 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 1.7
      AAA_22  79 lealeqalraravielliiDEaqhlrseealeeL 112
                 +e++ q lr+ a+ ++++ +Ea+++  ++al+++
  EEA22126.1 797 METIGQILRSDAASRAILAEEAENV-DDAALKDI 829
                 456667777776689*********9.78887765 PP

  == domain 3  score: 8.6 bits;  conditional E-value: 0.0015
      AAA_22    7 ilvvtGesGtGKTtllrrlleqldeeakaee.....................erpevv.....fvtlpsstsskdllrellralglelka....... 70  
                   +++ +++G+GKT++++  l ++  +++ ++                     +r + +      v+l                      +       
  EEA22126.1 1398 AVFLAAPAGSGKTVCAELALLRH--WSQSDKgravyiapfqelidsryndwsKRLSSIaggktIVKL----------------------Tgettadl 1470
                  577899***********999998..655555546665544444444444444222222333222222......................13333334 PP

      AAA_22   71 ...........erlsseellealeqalraravielliiDEaqhl 103 
                              + + + l ++ ++  + + v +l+i DE + +
  EEA22126.1 1471 klldsadlvlaTPVQWDVLSRQWQRRKNVQTV-GLFIADELHMI 1513
                  44444444443366777777777777777777.99999998876 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.0     0.015        23       3      99 ..     532     670 ..     530     686 .. 0.65
   2 !   17.6   0.0   1.6e-06    0.0024       2     100 ..    1381    1513 ..    1380    1516 .. 0.64

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.015
      AAA_30   3 naeQaaavealltsgdrvavltGpAGtGKt..talkalreaweaag..........grviglAptgkaAkv.La..............eelgieastia 74 
                 n  Q +   ++ +++   +++ +p G+GKt   +l+ lre+ ++++          ++++ +Ap ++  ++ ++              e       t +
  EEA22126.1 532 NRIQTKCYPTAFHDDG-NMLVCAPTGSGKTnvAMLTMLREIGKNRNpntgeimlddFKIVYIAPLKALVQEqVGnfgkrlqpygirvsE------LTGD 623
                 5666666666666554.68999********44368888999999867999****99999999999998887566444444332222220......2222 PP

      AAA_30  75 kllkrlk......................grarlepgtllivDEagm 99 
                 + l++++                      +    +  +lli+DE+ +
  EEA22126.1 624 RQLTKQQiadtqiivttpekwdvitrkatDSSYTKLVRLLIIDEIHL 670
                 33322224555555556666666666776433444448888888765 PP

  == domain 2  score: 17.6 bits;  conditional E-value: 1.6e-06
      AAA_30    2 lnaeQaaavealltsgdrvavltGpAGtGKttalkal.reaweaa.ggrviglAptgkaAkvLae......elgieastiakllkrlk......... 81  
                  +n  Q++a+++l +s++  ++l +pAG+GKt   + +  ++w ++ +gr + +Ap ++  +   +      ++ + ++ti kl+ +++         
  EEA22126.1 1381 FNRIQSQAFKSLFESDE-AVFLAAPAGSGKTVCAELAlLRHWSQSdKGRAVYIAPFQELIDSRYNdwskrlSSIAGGKTIVKLTGETTadlklldsa 1476
                  5778**********997.99************99876688888887889999998766554422211111111124555555555555555555555 PP

      AAA_30   82 ..................grarlepgtllivDEagmv 100 
                                    +r+++++  l+i DE  m+
  EEA22126.1 1477 dlvlatpvqwdvlsrqwqRRKNVQTVGLFIADELHMI 1513
                  6666666666666666554445555566666666665 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.5   0.0    0.0065       9.8       4      51 ..     526     574 ..     525     693 .. 0.56
   2 !    9.3   0.0   0.00093       1.4      14      61 ..    1387    1435 ..    1379    1482 .. 0.74

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0065
      AAA_16   4 GReeeleqL.lsalervrsgrpelvllsGesGvGKsslv.rellralekd 51 
                 G  +el+++ + ++ ++  ++ +++l+  + G+GK+ ++  + lr++ k+
  EEA22126.1 526 GSSKELNRIqTKCYPTAFHDD-GNMLVCAPTGSGKTNVAmLTMLREIGKN 574
                 677899999555555666666.8999**********99965555677777 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.00093
      AAA_16   14 salervrsgrpelvllsGesGvGKsslv.rellralekdg.giflrgkcd 61  
                  +a++++ +++ e+v+l  ++G+GK+  +  +llr++++++ g +++    
  EEA22126.1 1387 QAFKSLFESD-EAVFLAAPAGSGKTVCAeLALLRHWSQSDkGRAVYIAPF 1435
                  5777777787.8****************5566689998843444444433 PP

>> PhoH  PhoH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.0     0.041        61      16      43 ..     543     570 ..     529     578 .. 0.74
   2 !   11.4   0.0   0.00011      0.16       7      58 ..    1383    1435 ..    1379    1441 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.041
                 HHH-SEEEEE--TTSSTTHHHHHHHHHH CS
        PhoH  16 lkkndivfaiGpaGtGKtylavalavea 43 
                  ++   + + +p+G+GKt +a+ + ++ 
  EEA22126.1 543 FHDDGNMLVCAPTGSGKTNVAMLTMLRE 570
                 44555677899**********9876665 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00011
                  HHHHHHHHHHH.H-SEEEEE--TTSSTTHHHHHHHHHHHHTTS-SEEEEEE-S CS
        PhoH    7 keQkeylealk.kndivfaiGpaGtGKtylavalavealkkkkvkriiltrpa 58  
                  + Q++++++l  + + vf ++paG+GKt  a  + ++ +++++  r +++ p 
  EEA22126.1 1383 RIQSQAFKSLFeSDEAVFLAAPAGSGKTVCAELALLRHWSQSDKGRAVYIAPF 1435
                  568888888875777****************9999999999998888888775 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.1   0.1    0.0087        13       9      31 ..     545     567 ..     539     687 .. 0.76
   2 !    7.9   0.0    0.0024       3.5      10     115 ..    1396    1514 ..    1385    1526 .. 0.62

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0087
      AAA_19   9 kekvllvtaGpGtGKTrvlkhiv 31 
                  ++++lv a+ G+GKT v +  +
  EEA22126.1 545 DDGNMLVCAPTGSGKTNVAMLTM 567
                 6789************9865433 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0024
      AAA_19   10 ekvllvtaGpGtGKTrvlkhi.vallvelggvkpeeillvaftgrAakelrerlaalgae..atTiHrlal........ldfddlltealelle... 92  
                  ++ +++ a++G+GKT + + + ++++ +  +   + ++++ f +   ++ ++  + l      +Ti +l+         ld  dl            
  EEA22126.1 1396 DEAVFLAAPAGSGKTVCAELAlLRHWSQSDK--GRAVYIAPFQELIDSRYNDWSKRLSSIagGKTIVKLTGettadlklLDSADL--------Vlat 1482
                  567899*********9987541566666654..4778887777777777777443333333456666664433322222333333........1345 PP

      AAA_19   93 .........eaeeekklqeeellivDEfqdvd 115 
                           + +++k++q   l+i DE  ++ 
  EEA22126.1 1483 pvqwdvlsrQWQRRKNVQTVGLFIADELHMIG 1514
                  55567777777788888555599999999986 PP

>> UvrD-helicase  UvrD/REP helicase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   0.0     0.001       1.5      12      42 ..     545     575 ..     534     587 .. 0.85
   2 ?    3.3   0.0     0.033        50       3      28 ..    1383    1411 ..    1381    1424 .. 0.78

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.001
                    -SSEEEEEE-TTSSHHHHHHHHHHHHHHTSS CS
  UvrD-helicase  12 lggpilveAsAGsGKTfvlaerilrlikeee 42 
                      g++lv A  GsGKT v +  +lr i +++
     EEA22126.1 545 DDGNMLVCAPTGSGKTNVAMLTMLREIGKNR 575
                    5799********************9998874 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.033
                     HHHHHHHHS...-SSEEEEEE-TTSSHHH CS
  UvrD-helicase    3 peqreaias...lggpilveAsAGsGKTf 28  
                     ++q +a +s   + + ++++A AGsGKT 
     EEA22126.1 1383 RIQSQAFKSlfeSDEAVFLAAPAGSGKTV 1411
                     6677777776557788999*********6 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   0.0   0.00072       1.1     124     156 ..     541     574 ..     525     584 .. 0.79
   2 ?    1.6   0.0     0.081   1.2e+02     116     150 ..    1383    1417 ..    1335    1433 .. 0.77

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00072
       T2SSE 124 kavrerglilvsGgTgsGKttll.yallkeinks 156
                 +a +  g++lv  +TgsGKt ++  ++l ei k+
  EEA22126.1 541 TAFHDDGNMLVCAPTGSGKTNVAmLTMLREIGKN 574
                 5667789*************77647788888776 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.081
       T2SSE  116 ekiaevlrkavrerglilvsGgTgsGKttllyall 150 
                    ++++ ++  ++   + ++ + gsGKt+ +  +l
  EEA22126.1 1383 RIQSQAFKSLFESDEAVFLAAPAGSGKTVCAELAL 1417
                  44555666666777899999*********996554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2208 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       482  (0.0268838); expected 358.6 (0.02)
Passed bias filter:                      375  (0.0209158); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 1.17u 0.29s 00:00:01.46 Elapsed: 00:00:00.50
# Mc/sec: 13387.49
//
Query:       EEA22127.1  [L=1005]
Description: DNA mismatch repair protein Msh1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-73  246.4   0.0    4.5e-73  245.3   0.0    1.6  1  MutS_V    MutS domain V
    6.9e-44  150.4   6.5    1.6e-43  149.2   6.5    1.6  1  MutS_III  MutS domain III
    1.5e-20   73.5   0.0      4e-20   72.1   0.0    1.8  1  MutS_I    MutS domain I
      3e-06   27.6   0.0    8.6e-06   26.1   0.0    1.8  1  MutS_II   MutS domain II
  ------ inclusion threshold ------
       0.07   13.5   0.1       0.18   12.2   0.1    1.8  1  MutS_IV   MutS family domain IV
       0.14   12.4   1.2        2.3    8.5   0.0    3.2  4  AAA_28    AAA domain
       0.39   11.2   4.1        3.8    8.0   0.0    2.8  2  AAA_23    AAA domain
       0.91    9.2   5.1        1.1    9.0   0.8    2.5  2  DUF2312   Uncharacterized protein conserved in bacteria (DUF2


Domain annotation for each model (and alignments):
>> MutS_V  MutS domain V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  245.3   0.0     2e-76   4.5e-73       1     187 [.     795     982 ..     795     983 .. 0.98

  Alignments for each domain:
  == domain 1  score: 245.3 bits;  conditional E-value: 2e-76
                 EEEE-STTSSHHHHHHHHHHHHHHHHHT--BSSSEEEEE--SEEEEEE--------SS-HHHHHHHHHHHHHTT--TTSEEEEESTS-SS-HHHHHHHH CS
      MutS_V   1 llitGpnmaGkstylrqvalivllaqiGsfvpaekaeisivdkiftRvgasDdlakgkstFmvEmlEtasilknatekslvilDElGRGtstydGlaia 99 
                 +litGpnm+Gkst+lrq+ali++laq+Gsfvpae+aei+ivd++f+R+ga+Ddl +++stFmvEmlEta+ilk+at +s+vi+DE+GRGt+ +dG+a+ 
  EEA22127.1 795 WLITGPNMGGKSTFLRQNALITILAQVGSFVPAEYAEIGIVDQVFSRIGAADDLFRDQSTFMVEMLETAAILKQATPRSFVIMDEVGRGTTPEDGTAVG 893
                 69************************************************************************************************* PP

                 HHHHHHHHHTT--EEEEEES-GGGGGHHHHSTTEEEEEEEEEEET.TEEEEEEEEEES--SS--HHHHHHHTT--HHHHHHHHHHHHHT CS
      MutS_V 100 lavaeyllekikaktlfatHyheltklaekleevknlhlavkeee.edivflykvkegaaeksyGikvaklaglPesvverArevlkel 187
                 +a++e+l + ++++tlfatH+h l +++  +e+++ +  +vke+   ++ f++k+++g++++s+ +kva+laglPe+ ++ A++vl+++
  EEA22127.1 894 YACLEHLYNVNQCRTLFATHFHALIDMTVGFEKLSAYCTDVKESPsGSFSFVHKLRKGVNRQSHALKVARLAGLPEAAITVAENVLRQM 982
                 ******************************************887599*************************************9987 PP

>> MutS_III  MutS domain III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  149.2   6.5     7e-47   1.6e-43       1     191 []     381     741 ..     381     741 .. 0.97

  Alignments for each domain:
  == domain 1  score: 149.2 bits;  conditional E-value: 7e-47
                 HHHHHTTSSS-TTS.SSSS-HHHHH---SSHHHHHHHHHHHH--BS-HHHHHHHHHHHHH.T..TT.HHHHHHHHTT---HHHHHHHHHTT---HHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    MutS_III   1 aTlrnLeilenlrggskegsLlgvldrTvTamGaRlLrewllqPltdleeInaRldaVee.leneelreelrellrrlpDleRllsrislgkakardlk 98 
                 ++lr Leile+ r+g  +gsLl++++rT T++GaRlLr +l +P+t+l++I++Rld+V++ l++ee+r+++ +ll+r++D +Rl+++++lg+++++dl 
  EEA22127.1 381 SSLRGLEILETARDGLGKGSLLHAVRRTATKSGARLLRDRLISPSTSLSVIQERLDLVTYfLQDEEIRDTIISLLKRSYDSQRLVQKFTLGRGDPDDLI 479
                 589********99985699****************************************99************************************** PP

                 HHHHHHHHHHTTTTT---SSTHHHHH....................HHHHHHHHHHB-SS--SSGGGS--B-T.......................... CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxx....................xxxxxxxxxxxxxxxxxxxxxxxxxxx.......................... RF
    MutS_III  99 allealkaleelvallekeklaesee....................eslaelleeaideeplalekegedlra.......................... 151
                  l +a++a+ e  ++l++ ++++ +e                    ++lae +  aidee+l ++++ ed++a                          
  EEA22127.1 480 YLSRAIEASREVLRALSNRQTNPTSEtdtnrqsvdnlirrlhldgpTQLAEKILAAIDEEALLQKHRIEDSQAaeaaqltqdvvlseglpedvesmprk 578
                 ********99999999998888777799**********999999987788788888******************************************* PP

                 ................................................................................................... CS
                 ................................................................................................... RF
    MutS_III 152 ................................................................................................... 151
                                                                                                                    
  EEA22127.1 579 vrfkttgrpgfavdsirgdidiwimrrdasnalrrlherldeleeeksaltnrlqedagssaltlkwspslgyichvkgakisqealedlgvtrivsst 677
                 *************************************************************************************************** PP

                 ........................HHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHH CS
                 ........................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    MutS_III 152 ........................iealeqelfqelleeveealerlrrlaealaeLDvllSlA 191
                                         i+a+eq++f+el++ev  +l ++rr+a++++eLDv++S+A
  EEA22127.1 678 kstrsfylpawsqlgerldklkkhIRAEEQQIFEELRREVILNLVKIRRNASVMDELDVACSFA 741
                 ****************************************999********************9 PP

>> MutS_I  MutS domain I
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.1   0.0   1.8e-23     4e-20      11     112 ..      97     203 ..      89     204 .. 0.90

  Alignments for each domain:
  == domain 1  score: 72.1 bits;  conditional E-value: 1.8e-23
                 CHH-TTCEEEEEETTEEEEECHHHHHHHHHCSSSSTT.ESSSSC.EEEEEEEHHHHHHHHHHHHHT.T-EEEEEEE-S-HHHHS......S--EEEEEE CS
      MutS_I  11 kkkykdavlffrvGdfYelfgeDAviaareleitltkrkkssekeipmagvPehalekylrkLvek.gykVavveqtetpaekkg.....vvkrevvrv 103
                  +k k++v++ rvG+fYel+ e+A+  a +l+i+l ++k++++  +pmag+P  +l+++l+ Lv+  ++ Va+ e   +p e+k+     +++r+v+rv
  EEA22127.1  97 MEKFKNCVVLTRVGSFYELYWEQAEELAPLLNIKLASKKTNAGP-VPMAGFPFFQLDRFLKILVQDlQKYVALSEEFLNPVEEKSksgglLFDRRVTRV 194
                 46799*******************************88876666.********************88*********99998885334578********* PP

                 EBTTC-TTS CS
      MutS_I 104 iTpGtltde 112
                 iTpGtl+de
  EEA22127.1 195 ITPGTLIDE 203
                 ******997 PP

>> MutS_II  MutS domain II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.1   0.0   3.8e-09   8.6e-06      12      61 ..     245     293 ..     236     353 .. 0.86

  Alignments for each domain:
  == domain 1  score: 26.1 bits;  conditional E-value: 3.8e-09
                 TSEEEEEEEETTTTEEEEEEEEE-HHHHHHHHHH-ESEEEEESS-SCCCH CS
     MutS_II  12 grrvGlafiDlstgefvvsefedfeeleaeLsrlsPkElllpedlsesta 61 
                   rvGla++Dlstg+f+++ ++  + l + ++r++++E+++++ l +  a
  EEA22127.1 245 TGRVGLAWMDLSTGDFYTQVTT-TQMLPSAIARIGAREIVADQRLQNLLA 293
                 4569***************887.6******************99976654 PP

>> MutS_IV  MutS family domain IV
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.1   8.1e-05      0.18       5      91 ..     610     700 ..     606     716 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 8.1e-05
                 HHHHHHHHHHHHHHHHHHHHCCCCCCCT-TTBEECCCSSSEEEEEE-TCC..CTTT--..SEEEEEECTCEEEEECCCHHHHHHHHHHHHH CS
     MutS_IV   5 eLdelrdrleelekeleeleekereklgikslkveynkvlGyylevtrse..akkvpk..efirlqtlknseryttaelkkleaelleaee 91 
                  L  l++rl+ele+e  +l  +++e+ g + l ++ ++ lGy  +v   +   + +++    ++++++k+ + ++ +  ++l ++l ++++
  EEA22127.1 610 ALRRLHERLDELEEEKSALTNRLQEDAGSSALTLKWSPSLGYICHVKGAKisQEALEDlgVTRIVSSTKSTRSFYLPAWSQLGERLDKLKK 700
                 68899******************************************88864455588999999********************9998875 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       4.5     1e+04      25      49 ..     329     353 ..     316     372 .. 0.81
   2 ?   -0.0   0.2      0.41   9.1e+02      32      79 ..     518     566 ..     486     572 .. 0.62
   3 ?   -1.9   0.0       1.6   3.5e+03     109     149 ..     679     718 ..     651     737 .. 0.57
   4 ?    8.5   0.0     0.001       2.3       3      79 ..     796     878 ..     795     882 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 4.5
      AAA_28  25 pvvpEaareileeklakgedalpwv 49 
                 pv  E+a ++++e+ a g++ l++v
  EEA22127.1 329 PVPSETASTFTNEEVAAGFNLLEYV 353
                 5668999999999999999988876 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 0.41
      AAA_28  32 reileekl.akgedalpwvedllafaervleeqleeeaaaaankvlfcD 79 
                 r++  ++  +  e++l++ ++   ++++++e   ++eaa+ +++v++++
  EEA22127.1 518 RRLHLDGPtQLAEKILAAIDEEALLQKHRIEDSQAAEAAQLTQDVVLSE 566
                 4433333324455566666677778888888888888888888888876 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 1.6
      AAA_28 109 ydlvfllppapei..dddgeRredleereaiderlrealrelg 149
                  ++ f+lp +  +  + d+  +   + r++ +++++e+ re  
  EEA22127.1 679 STRSFYLPAWSQLgeRLDKLKK---HIRAEEQQIFEELRREVI 718
                 5556666666666222222222...334444555554444443 PP

  == domain 4  score: 8.5 bits;  conditional E-value: 0.001
      AAA_28   3 vitGgestGKTtll......eaLaargypvvpEaareileeklakgedalpwv.edllafaervleeqleeeaaaaankvlfcD 79 
                  itG+  +GK+t l        La+ g  v +E+a   + ++ +++ +a+++  +d   f  ++le + + +++a+++ ++++D
  EEA22127.1 796 LITGPNMGGKSTFLrqnaliTILAQVGSFVPAEYAEIGIVDQVFSRIGAADDLfRDQSTFMVEMLETA-AILKQATPRSFVIMD 878
                 59**********9944333344556688888********************9999********99866.688999999999998 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   2.2      0.11   2.4e+02     153     179 ..     551     635 ..     391     714 .. 0.62
   2 ?    8.0   0.0    0.0017       3.8      21      37 ..     794     810 ..     783     833 .. 0.86

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.11
      AAA_23 153 e..........................................................rleelekeleeledekkllekleqek 179
                 +                                                          +l+ l + l+ele+ek+ l +++qe 
  EEA22127.1 551 QaaeaaqltqdvvlseglpedvesmprkvrfkttgrpgfavdsirgdidiwimrrdasnALRRLHERLDELEEEKSALTNRLQED 635
                 0222333334444555555555555555666666667776666666666666666666688888888888888888888776554 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0017
      AAA_23  21 ltlItGpNGaGKTTild 37 
                 + lItGpN  GK+T+l+
  EEA22127.1 794 IWLITGPNMGGKSTFLR 810
                 679************94 PP

>> DUF2312  Uncharacterized protein conserved in bacteria (DUF2312)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.8   0.00048       1.1       2      27 ..     608     633 ..     607     635 .. 0.89
   2 ?    1.4   0.2      0.11   2.5e+02      13      35 ..     693     715 ..     691     731 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00048
     DUF2312   2 adqLrqfieRiErleeEkkaiaedik 27 
                 ++ Lr++ eR+++leeEk+a+++ ++
  EEA22127.1 608 SNALRRLHERLDELEEEKSALTNRLQ 633
                 689******************99876 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.11
     DUF2312  13 ErleeEkkaiaedikdvyaeaKs 35 
                 Erl++ kk+i ++ +++++e + 
  EEA22127.1 693 ERLDKLKKHIRAEEQQIFEELRR 715
                 89999999999999999999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1005 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       810  (0.0451782); expected 358.6 (0.02)
Passed bias filter:                      650  (0.0362541); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.82u 0.31s 00:00:01.12 Elapsed: 00:00:00.47
# Mc/sec: 6428.35
//
Query:       EEA22128.1  [L=368]
Description: ureidoglycolate hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.1e-61  205.1   0.0    3.3e-29  102.0   0.0    2.2  2  Ureidogly_lyase  Ureidoglycolate lyase


Domain annotation for each model (and alignments):
>> Ureidogly_lyase  Ureidoglycolate lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.0   0.0   1.8e-33   3.3e-29       2     109 ..      12     179 ..      11     188 .. 0.95
   2 !  101.0   0.0   3.8e-33   6.8e-29     110     186 ..     216     346 ..     205     347 .. 0.95

  Alignments for each domain:
  == domain 1  score: 102.0 bits;  conditional E-value: 1.8e-33
  Ureidogly_lyase   2 krikiepLtkeaFapFGdvieape................eakkappesvaiNqgtalkyhdlaelenays...pskkearavislfrcaprel 76 
                       ri++epLt++ FapFG+vi++p                 +++  p+++v +Nqg+a+k++++a+l n y+   ps k+a+a++s+f c+pr+l
       EEA22128.1  12 LRITPEPLTPQSFAPFGTVITTPFprdllgapnnlpslklPHR-VPATPVYANQGSAVKISPIAPLANGYEnacPSGKAAQARLSMFACFPRKL 104
                      589*******************8899**********9975444.6999**********************99********************** PP

  Ureidogly_lyase  77 pake..........................................ekklldvkilErHpftsQtFvPlglsske 109
                      ++++                                          e  ++dv+ilErHpft+QtF+Pl+lss++
       EEA22128.1 105 RREKqqaaahhtatgvndillngkikinkgqqdgddddgrdadaefEGPVFDVRILERHPFTTQTFIPLDLSSQK 179
                      *8889***************************************99999**********************8885 PP

  == domain 2  score: 101.0 bits;  conditional E-value: 3.8e-33
  Ureidogly_lyase 110 k...aylvvVAptlk..................................................rglpdlkklraFvakgaqaVtygagvWHa 150
                      +    +lv+VAptlk                                                  r++pdl++lraF+a+g+qaVtyg g+WHa
       EEA22128.1 216 QeepIFLVIVAPTLKgqsaaattspsnkninsvssdpttnimstigtlsdgsvnegssnsnrvliRDPPDLENLRAFIARGGQAVTYGPGTWHA 309
                      13469***************************************************************************************** PP

  Ureidogly_lyase 151 plvvlgdkpidFvvvq.adrvaeedceevlleeelav 186
                      p+vvlg +++dFvvvq +++v++edc+e++++++++v
       EEA22128.1 310 PMVVLGPRRVDFVVVQyVNGVNDEDCQEAAFKDGIVV 346
                      ********************************99887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (368 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       388  (0.0216409); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.29s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 2413.23
//
Query:       EEA22129.1  [L=1196]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.8e-27   96.5   0.0    3.3e-27   95.7   0.0    1.3  1  SGL           SMP-30/Gluconolactonase/LRE-like region
    3.2e-06   27.2   5.0    8.5e-06   25.8   5.0    1.7  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
    6.5e-06   25.4   0.0    2.6e-05   23.4   0.0    1.8  1  Fungal_trans  Fungal specific transcription factor domain
    1.2e-05   25.4   0.0      5e-05   23.4   0.0    2.0  2  Arylesterase  Arylesterase
    0.00012   22.1   0.0    0.00035   20.6   0.0    1.8  1  Str_synth     Strictosidine synthase


Domain annotation for each model (and alignments):
>> SGL  SMP-30/Gluconolactonase/LRE-like region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.7   0.0   9.1e-31   3.3e-27      52     233 ..      94     296 ..      62     301 .. 0.80

  Alignments for each domain:
  == domain 1  score: 95.7 bits;  conditional E-value: 9.1e-31
         SGL  52 grlvvasksgl......alldlas.geletladeeedekpllrfNDgvvdpdGrlwfGtmgdeeakgeev.....galyrldpd.gklervlddltipN 137
                 ++++++s+++       + +++++  + et++d++ ++ + +++ND+vv++dG++wf+++ ++ +++ ++      ++yr+dp+ ++++ ++d++  pN
  EEA22129.1  94 DGVLFCSQGTAtqpsslVWMKIEEpYQCETIIDSFYGR-QFNSLNDVVVHSDGSIWFTDPIYGFEQNFRPrpqlpSQVYRYDPGtKSIRAMADGFERPN 191
                 55555555544444432333333314799******999.**********************9999999889999**********999************ PP

         SGL 138 GlawspdgktlYlaDsltrk............iwaydvdaeggk..lsnrrvfadlkkgegepDGlavDaeGnvwvAvwgggkvvrfdpdGklieeikl 222
                 G+ +spd+k +Y++D+   +            i+a+dv    g+  l+nrr+fa  ++g   pDG+ +D eGnv++    g+++++++p G l++++ +
  EEA22129.1 192 GISFSPDEKVVYVTDTDLVHgdgsidlhrvstIYAFDVVHRHGQpfLTNRRLFAMADNG--IPDGIKCDLEGNVYSG--CGDGIHVWSPGGVLLGKMLI 286
                 *************7775433334444444557******998877558******888877..5***************..5699**************** PP

         SGL 223 pakrvtscaFg 233
                 p   v++ +F 
  EEA22129.1 287 P-GGVANFCFT 296
                 *.899999994 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   5.0   2.4e-09   8.5e-06       1      32 [.     488     525 ..     488     531 .. 0.85

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 2.4e-09
                 SS-HHHHHCT---ST.......SSSS-HHHHHCTHHHCC CS
     Zn_clus   1 haCdnCrkkKvKCda.......kkPaCsnCkklnleCtf 32 
                 +aC +Cr++K+KC         + P C++C++ ++eC+ 
  EEA22129.1 488 RACVRCRRHKTKCILqlagsvaGPP-CQKCVEAGVECVL 525
                 69***********998888886666.***********94 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.4   0.0   7.3e-09   2.6e-05       2     174 ..     668     831 ..     667     837 .. 0.81

  Alignments for each domain:
  == domain 1  score: 23.4 bits;  conditional E-value: 7.3e-09
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsL. 97 
                   +r+   +hp +pi+   ++ ++       ++a  +p+ll+ail ++a    + + ++      + + ++ ++l  ei+         + ++++++L 
    EEA22129.1 668 ERYAATYHPFYPIVPAKTLARTS----LDETARREPHLLTAILTIAAKDIVNGEPIQ------KICAQYMQCLVSEIIA-----GKKCGVEAVEALl 749
                   6899999*********9999999....99999**************98877777777......2234566899999999.....6677799***762 PP

  Fungal_trans  98 lllelyektssdralher..........hhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrpp 174
                   ll+e++  +  + ++  +          h+g+a+r+a+ l+L r  ++  +       +    + +  w+a++  D++i++  Grp+
    EEA22129.1 750 LLAEWVPPGVHSEPARGYcgnedmaawmHIGLAIRIAYILRLDRAMFDDLR-----NGIVSLSREKYAWLACYLSDRQISVRIGRPF 831
                   6667887777753333333555555556*********************95.....777777777999*****************97 PP

>> Arylesterase  Arylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.4   0.0   1.4e-08     5e-05      35      72 ..     167     206 ..     146     211 .. 0.87
   2 ?   -3.7   0.0       4.1   1.5e+04      52      69 ..     972     989 ..     966     990 .. 0.89

  Alignments for each domain:
  == domain 1  score: 23.4 bits;  conditional E-value: 1.4e-08
  Arylesterase  35 wtavvYysp..sevkvvasglssanGInidadkkyiyvad 72 
                   +++v+ y+p  + ++ +a+g++ +nGI +++d+k++yv+d
    EEA22129.1 167 PSQVYRYDPgtKSIRAMADGFERPNGISFSPDEKVVYVTD 206
                   688999999334578899*********************8 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 4.1
  Arylesterase  52 glssanGInidadkkyiy 69 
                    ++s +G +  +d ++iy
    EEA22129.1 972 EVDSTTGTGSLPDARFIY 989
                   68999************9 PP

>> Str_synth  Strictosidine synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.6   0.0   9.8e-08   0.00035      37      76 ..     168     207 ..     137     211 .. 0.83

  Alignments for each domain:
  == domain 1  score: 20.6 bits;  conditional E-value: 9.8e-08
   Str_synth  37 GrllkydkstkvvkvlldkLyfanGialsedgsfvlvcet 76 
                  ++++yd+ tk+++ ++d    +nGi+ s+d++ v v++t
  EEA22129.1 168 SQVYRYDPGTKSIRAMADGFERPNGISFSPDEKVVYVTDT 207
                 579******************************9998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1196 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       443  (0.0247086); expected 358.6 (0.02)
Passed bias filter:                      391  (0.0218082); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.85u 0.32s 00:00:01.17 Elapsed: 00:00:00.53
# Mc/sec: 6811.56
//
Query:       EEA22130.1  [L=306]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
  ------ inclusion threshold ------
      0.052   13.3   0.0       0.12   12.1   0.0    1.6  2  SBP_bac_11  Bacterial extracellular solute-binding protein


Domain annotation for each model (and alignments):
>> SBP_bac_11  Bacterial extracellular solute-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0      0.11     2e+03     128     166 ..      37      85 ..      19      90 .. 0.63
   2 ?   12.1   0.0   6.7e-06      0.12     154     228 ..     188     265 ..     116     267 .. 0.80

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.11
                 --HHHHHHHHHTEEEEESSH...........HHHHHHHHTTT-SEEEEEH CS
  SBP_bac_11 128 gaqellkalekkvvklgess...........rqlltaveageadagivye 166
                 g+ +l+kal+++   +++s+           r++  a+ +g +d++++ye
  EEA22130.1  37 GGTGLVKALAQNYL-SSNSIqgsiewicnhsRNTQLALFNGYIDIALTYE 85 
                 44778999999988.55555344445554444444445566666666666 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 6.7e-06
                 HHTTT-SEEEEEHHHHH.....HSTTSSEEE.E--TTT--...EEEEEEEE-TT--HHHHHHHHHTTSHHHHHHHHHTT CS
  SBP_bac_11 154 veageadagivyeseakaa...engdkleav.ylpeglnldpldypaavlkkaakreaAraFlafLrspeaqailrkyG 228
                 v+a+  ++++v +s  + +    + +k +++ ++   l+   +   +a+ + +++++  + F+af++s ++q++++++G
  EEA22130.1 188 VAANANAYLLVDRSTFLSQlsrRAFTKMSVFfEPTNPLHY-LMNSCYALYNPNPDNKHIEGFIAFIKSNAGQEVIASFG 265
                 5555566666666666544544566666666699999987.67888899999999*********************999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (306 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       392  (0.021864); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 2138.06
//
Query:       EEA22131.1  [L=530]
Description: AMP dependent CoA ligase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      2e-82  277.1   0.0    1.1e-81  274.7   0.0    1.8  1  AMP-binding    AMP-binding enzyme
    7.4e-14   52.5   0.1    1.8e-13   51.2   0.1    1.7  1  AMP-binding_C  AMP-binding enzyme C-terminal domain


Domain annotation for each model (and alignments):
>> AMP-binding  AMP-binding enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  274.7   0.0   1.2e-85   1.1e-81       1     422 [.      22     427 ..      22     428 .. 0.87

  Alignments for each domain:
  == domain 1  score: 274.7 bits;  conditional E-value: 1.2e-85
                  HHHHHHHST.TSEEEEECCSTEEEEHHHHHHHHHHHHHHHH.HTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTES CS
  AMP-binding   1 leeqaaktp.dkvalvdsgegqtlTYreldervnrlAagLr.slGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseak 96 
                  +++q + +p  +v l+d  +g+++T+ +l++ +  l++ L+ +l  + gd+  i++ n ++   ++ ++l +G+vv+p+np+++a el + l+ s++k
   EEA22131.1  22 FQRQNRSFPgSQVILTDVRTGRRYTFDDLRKLSLHLGSRLQeRLQWRTGDVLTIVSMNAIDIPPIIWGTLAIGGVVSPVNPNFSATELVHYLKVSQSK 119
                  78999999966666666779*********************99******************************************************* PP

                  EEEETCTCCC.HHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS..........-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHH CS
  AMP-binding  97 vliatvdsel.leklleaaakleavklvivldadellkeeelkeeeeseekae..........kpeeeeelkpddlayiiYTSGTTGkPKGVmlshrn 183
                  +++  +++ + ++ +++a+++  a++ +iv+d+   +++    +++ ++ + +          ++  + +  +++la+++++SGTTG PKGVmlsh n
   EEA22131.1 120 AIV--TQKSQyAKVAQAAEGAGLAKDRIIVIDDTT-EFS----GDSIWQPDPYlipdykftsvHK-SPITRPKEELAFLVFSSGTTGLPKGVMLSHTN 209
                  ***..999998888888888888888888888433.333....2332332222345678888644.34367779************************ PP

                  HHHHHHHHH.HHHCSCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHC CS
  AMP-binding 184 lvanvaslk.letrfklkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkak 280
                  +van+ +++ + +   l+++d+ l++lp++hi+g+++ +++ l+ G++ +++p+++    + +++++++ k+t++++vP v+ ++++++  +    ++
   EEA22131.1 210 IVANLLQMEaV-DAGYLDSTDRALAFLPFFHIYGITCLINYGLFLGMSTYIMPRFDL---ESFCNVVQNQKITYVYAVPPVVLQIVQNPIVE----KY 299
                  *******9743.3466888**********************************9988...3478***********************98887....56 PP

                  CGTT-SEEEEESS-EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBEETTSE.EEEEEEETTS-SE CS
  AMP-binding 281 dlsslrlvllggeplspellrffralfgeevlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeetgepvpdgee.Gellvrgpgvmkg 377
                  +lss+rl+ ++++pl+ el+r +r +fg ++ + Y           ++ e+d + +g vG+ +p+v +k v  + ge+v++g   Gel+v+gp+v+ g
   EEA22131.1 300 NLSSIRLINCAAAPLPTELIRTLRTKFGLSIRQQY-----------DQ-EGD-EHPGAVGRLVPNVTAKYVPIA-GEEVRPGRAeGELWVKGPNVFLG 383
                  9**************************99888844...........44.333.579*****************9.7777777666************* PP

                  BTT-HHHHHHHEEETCCEEEEEEEEEEETTSEEEEEEECCCEEEE CS
  AMP-binding 378 YlkkpeataeafdsegrwlrTGDlgrldedGyleivgRkkdlikl 422
                  Yl++p+at+e+f   +++++TGD+g+ d+ G++ +++R+k+lik 
   EEA22131.1 384 YLNNPAATKESFS-RDGFYKTGDIGYEDAYGNFVLTDRIKELIKY 427
                  ************7.657***********9**************96 PP

>> AMP-binding_C  AMP-binding enzyme C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.2   0.1     2e-17   1.8e-13       1      76 []     436     516 ..     436     516 .. 0.92

  Alignments for each domain:
  == domain 1  score: 51.2 bits;  conditional E-value: 2e-17
                    HHHHHHHSSTTEEEEEEE-----TTS.---EEEEEE---.---..HHHHHHHHHHHHT-TTTS-S.EEEE-S---B-TTS- CS
  AMP-binding_C   1 evEsalvshpaVaeaaVvGvpdevkG.ealvafVvlkdg.sea..leeeLkahvrkelgpyavpk.kvvfvdelpktrsGK 76 
                    e+Es l+ hpaVa++aVvG+p    G e + a++  k++ + +  ++++++++vr ++ +y+  +  v+fvd++p++  GK
     EEA22131.1 436 ELESLLLGHPAVADVAVVGIPSGQAGsELPRAYIKAKENsQGDrkTADDIVEYVRVRVVAYKQLRgGVHFVDAIPRNPAGK 516
                    89************************999*******8764322469****************9999**************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (530 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       434  (0.0242066); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 3622.76
//
Query:       EEA22132.1  [L=762]
Description: cutinase transcription factor 1 beta, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.5e-23   82.0   0.4    7.9e-23   80.8   0.4    1.5  1  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.8   0.4   4.4e-27   7.9e-23       2     177 ..     142     307 ..     141     321 .. 0.93

  Alignments for each domain:
  == domain 1  score: 80.8 bits;  conditional E-value: 4.4e-27
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLl 98 
                     +f+++++ +p+l+ ++flp     n+ + a+ s +ll a++  G+ f+++++ +    +t+       f+ ra+ l+  +++++ + ++ lq++l
    EEA22132.1 142 RAYFQWSYNFMPVLDIQDFLPAI--VNNDPDANISLFLLQAVMFAGSAFADMNHLRAGGFHTRRE-ARKEFFTRARLLY--HLEYEGDPICRLQAFL 233
                   67*********************..9999***************************999999877.88899********..888888889******* PP

  Fungal_trans  99 llelyektssd.ralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrpplld 177
                   ll + +    + ++  + ++g+  + a+s+gLhr+ps+         + + +  rrRlww+ F  D+++al l+rp+  +
    EEA22132.1 234 LLTYNNERDNSmQNDIWFWLGLCNTQAQSIGLHRDPSNLD------MDSARKRLRRRLWWCLFARDRMVALALRRPTQVN 307
                   ****99999999****************************......99999*************************9544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (762 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       387  (0.0215851); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.29s 00:00:00.97 Elapsed: 00:00:00.49
# Mc/sec: 4682.04
//
Query:       EEA22133.1  [L=309]
Description: lectin precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.9e-13   50.6  77.7    3.8e-05   24.1  18.5    4.0  4  Chitin_bind_1  Chitin recognition protein
  ------ inclusion threshold ------
        0.2   11.6   0.0       0.34   10.9   0.0    1.2  1  Syndecan       Syndecan domain


Domain annotation for each model (and alignments):
>> Chitin_bind_1  Chitin recognition protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1  18.5   4.2e-09   3.8e-05      10      36 ..      24      51 ..      21      56 .. 0.88
   2 !   22.5  21.7   1.3e-08   0.00012       1      37 [.      69     108 ..      69     112 .. 0.94
   3 !   15.7  21.0   1.8e-06     0.016       2      37 ..     154     193 ..     153     197 .. 0.85
   4 ?    0.5   1.1     0.099   8.9e+02      16      25 ..     190     199 ..     190     202 .. 0.83

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 4.2e-09
                   --ST.T-EE-TTSBEEBSHHHHSTT--B CS
  Chitin_bind_1 10 tCpl.nvCCSqyGyCGttsdyCgagCqs 36
                   +C++ + CCS  G+CG+ts+yCg gCqs
     EEA22133.1 24 SCSTyGDCCSTKGFCGSTSAYCGPGCQS 51
                   5755489********************9 PP

  == domain 2  score: 22.5 bits;  conditional E-value: 1.3e-08
                    B-SGGCTT---...STT-EE-TTSBEEBSHHHHSTT--BS CS
  Chitin_bind_1   1 eCGkqaggatC...plnvCCSqyGyCGttsdyCgagCqsn 37 
                    +CG+   ++tC   + + CCS+ GyCG    yCg+gCqs+
     EEA22133.1  69 SCGSAGSNYTClgsTFGDCCSSLGYCGGNLSYCGDGCQSG 108
                    5**********9877899********************96 PP

  == domain 3  score: 15.7 bits;  conditional E-value: 1.8e-06
                    -SGGC.TT---...STT-EE-TTSBEEBSHHHHSTT--BS CS
  Chitin_bind_1   2 CGkqa.ggatC...plnvCCSqyGyCGttsdyCgagCqsn 37 
                    CG ++   atC   + ++CCS +G+CG    yC++gCq++
     EEA22133.1 154 CGGNSdVFATClgsEWGNCCSTHGFCGGNISYCSTGCQTQ 193
                    887763559998876799********************86 PP

  == domain 4  score: 0.5 bits;  conditional E-value: 0.099
                    EE-TTSBEEB CS
  Chitin_bind_1  16 CCSqyGyCGt 25 
                    C  qyG CG 
     EEA22133.1 190 CQTQYGNCGL 199
                    7789*****7 PP

>> Syndecan  Syndecan domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   3.8e-05      0.34       8      37 ..     220     250 ..     217     269 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 3.8e-05
    Syndecan   8 vlaav.iggvvvgllfaillvlflvYRmrKK 37 
                  +a++ +gg++ gl ++ llv +  +Rm+++
  EEA22133.1 220 AIAGIsVGGTIGGLAVIGLLVWLAFFRMKRR 250
                 678883556666666777999999****975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       924  (0.0515366); expected 358.6 (0.02)
Passed bias filter:                      353  (0.0196888); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.48
# Mc/sec: 1928.07
//
Query:       EEA22134.1  [L=1220]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.9e-17   61.8   0.2    1.3e-11   44.7   0.0    2.5  2  Glyco_transf_28  Glycosyltransferase family 28 N-terminal dom
    1.3e-05   24.2   0.0    2.2e-05   23.4   0.0    1.2  1  UDPGT            UDP-glucoronosyl and UDP-glucosyl transferas
    0.00015   22.0   0.0    0.00088   19.6   0.0    2.2  2  ATG_C            Autophagy-related protein C terminal domain
    0.00065   19.4   2.4     0.0017   18.1   2.4    1.8  1  UIM              Ubiquitin interaction motif
       0.01   15.9   0.1      0.031   14.3   0.0    1.8  2  Glyco_tran_28_C  Glycosyltransferase family 28 C-terminal dom


Domain annotation for each model (and alignments):
>> Glyco_transf_28  Glycosyltransferase family 28 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.7   0.0   3.6e-15   1.3e-11       1      66 [.     146     211 ..     146     223 .. 0.84
   2 !   14.6   0.1   7.2e-06     0.026      99     138 ..     272     311 ..     267     312 .. 0.89

  Alignments for each domain:
  == domain 1  score: 44.7 bits;  conditional E-value: 3.6e-15
                      EEEEE-SSHHHHHHHHHHHHHHHC.TT-EEEEEEETCCCHHHHHHCCT-EEEE---GHCTT...CHHH CS
  Glyco_transf_28   1 ivllggGTgGhvfPalAlakeLkk.egheVrylgtkrgleerlveeaglefepiageklrrkl.spkn 66 
                      +v+ ++G++G+v+P++Al k Lk+ +gh+Vr l+t++ +++++  e+glef +i+g++ r     +kn
       EEA22134.1 146 VVIQVVGSRGDVQPFVALGKVLKDtYGHRVR-LATHPIFKDFV-LEHGLEFFSIGGDPARLMAfMVKN 211
                      68999*****************9648*****.**********9.************954432214444 PP

  == domain 2  score: 14.6 bits;  conditional E-value: 7.2e-06
                      CCHCCCCCHCCCTTHCCCCCHCTS-ECCCCCCCCC-SCCC CS
  Glyco_transf_28  99 vslpaviaaplaripviihEqnaipglanktlsrtatkva 138
                      + ++ +ia+p++ ++++ +E+++ip ++ +t++  +t+ +
       EEA22134.1 272 FVADCIIANPPSFAHIHCAEKLGIPLHIMFTMPYSPTQFF 311
                      56789****************************9888765 PP

>> UDPGT  UDP-glucoronosyl and UDP-glucosyl transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.4   0.0   6.2e-09   2.2e-05     278     409 ..     427     561 ..     423     571 .. 0.86

  Alignments for each domain:
  == domain 1  score: 23.4 bits;  conditional E-value: 6.2e-09
       UDPGT 278 vvfSlGsmvseipeekanaiAsaLakipqkvlWr..fdgkkPstLaknt..llvkWlPqndlLgHPktkAFvtHaGangvyEaisnGvPmvglPlFgdq 372
                 +++ +Gs+v + p    + i +a+ k +q+vl +  + g   + L       +   +P   + +H  +   v H+Ga +   +i  G P  ++P+Fgdq
  EEA22134.1 427 IYIGFGSIVLDDPSAMTELIFEAVRKTGQRVLLSkgWGGLGADELHVPDgvFMLGNVPHDWVFRH--VSCVVHHGGAGTTAAGIAAGRPTLVVPFFGDQ 523
                 5789****************************764456677777765433388899*********..56799*************************** PP

       UDPGT 373 rdNikrmeakgaavt.lnvkemtsedllnAlkevindk 409
                 +   + ++  ga+   +  k++t + l  A++  ++ +
  EEA22134.1 524 HFWGATVARAGAGPDpIPYKQLTVDKLVDAINFCLKPE 561
                 ***********997548899999999999998777665 PP

>> ATG_C  Autophagy-related protein C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       1.8   6.5e+03      37      56 ..     793     812 ..     790     816 .. 0.80
   2 !   19.6   0.0   2.4e-07   0.00088       9      84 ..     843     918 ..     838     926 .. 0.92

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 1.8
       ATG_C  37 psevaeskgakgavkavvra 56 
                 p+ v+ skga+++vka+v+a
  EEA22134.1 793 PTGVHMSKGAGRFVKAIVKA 812
                 56677889999999999986 PP

  == domain 2  score: 19.6 bits;  conditional E-value: 2.4e-07
       ATG_C   9 edlreGlqqAysslskglksaaqtilavpsevaeskgakgavkavvravPvavlrPligateavsktlqGvrnqld 84 
                 +dlr+G +   +++  g     + +++ p + a+++ga+g+vk+v + +   + +P  ++  ++ +t+qGv+++++
  EEA22134.1 843 SDLRSGAKAVGREFGFGWYDGITGMVTHPWKGAQKEGASGFVKGVGKGIGGFIAKPSAAVLGILGHTMQGVSKEVQ 918
                 58888888888888889999999************************************************99876 PP

>> UIM  Ubiquitin interaction motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   2.4   4.8e-07    0.0017       1      16 [.    1194    1209 ..    1194    1210 .. 0.95

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 4.8e-07
         UIM    1 dEdedLqrAlalSlqE 16  
                  +EdedLq Al+lS+qE
  EEA22134.1 1194 QEDEDLQNALRLSMQE 1209
                  7*************** PP

>> Glyco_tran_28_C  Glycosyltransferase family 28 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   8.6e-06     0.031      73     155 ..     492     571 ..     485     581 .. 0.85
   2 ?   -3.6   0.6       2.6   9.5e+03      27      47 ..    1159    1179 ..    1141    1202 .. 0.42

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 8.6e-06
                      H-EEEECS-CHHHHHHHHTT--EEEE--TT....S-HHHHHHHHHHHHHHS.SEEEE-STTCHHHHHHHHCCS---S---SSCH CS
  Glyco_tran_28_C  73 adLvIsRAGagtiaEllalgkplIlvplpeaaenhqdnNakelekagaalv.leqkeltpekLeeallelaaeklrlaekskas 155
                       + v+ ++Gagt a   a+g p+++vp+      +q    + +++aga+   + +k+lt +kL++a+  ++++++ + +k+ a+
       EEA22134.1 492 VSCVVHHGGAGTTAAGIAAGRPTLVVPFFG----DQHFWGATVARAGAGPDpIPYKQLTVDKLVDAINFCLKPESLERAKKLAN 571
                      567999**********************99....9999**********97559******************9998655555554 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 2.6
                       HHHHHHCHHHCCT-E.EC---S CS
  Glyco_tran_28_C   27 lksrelqvlhqtGkr.eleevk 47  
                       +k  e+++++++ k+ +l e++
       EEA22134.1 1159 EK-TEEEIVIEYIKKqSLLEMQ 1179
                       11.1222222222221333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1220 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1086  (0.0605723); expected 358.6 (0.02)
Passed bias filter:                      488  (0.0272185); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.88u 0.32s 00:00:01.20 Elapsed: 00:00:00.49
# Mc/sec: 7520.15
//
Query:       EEA22135.1  [L=175]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.2e-23   81.4   9.3    7.6e-23   81.1   9.3    1.1  1  MARVEL    Membrane-associating domain


Domain annotation for each model (and alignments):
>> MARVEL  Membrane-associating domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.1   9.3   4.2e-27   7.6e-23       6     142 ..      12     150 ..       8     152 .. 0.92

  Alignments for each domain:
  == domain 1  score: 81.1 bits;  conditional E-value: 4.2e-27
      MARVEL   6 lgilrilqlvfaiiilgliaslia..............kldqllgspssalnfavfvavfsflyalfllvlylfknsaftsilwplidlivdalaallw 90 
                 +++lr lql+faii++g+ + +i               ++++ +   ++a++f +f+av+++l+++f l++ ++   +++++l+ +i ++v+a+a+l w
  EEA22135.1  12 DYALRALQLIFAIIVMGSDGHAIRefhghtvyehfqfgNYYD-YVGVPDAWSFLLFCAVWTLLIVIFHLIAGIY---FADRALIGYIRVGVEAVAVLSW 106
                 789**********************************95544.5555**************************8...8999****************** PP

      MARVEL  91 lvafialaaglrdiscafesnqysasltvrcgqaqaavafgflavllfaasa 142
                 l++fia+a+++ +  c        +  + +c  ++aa++fg+  +llf+++a
  EEA22135.1 107 LAGFIAVAIQIPTGTC--------SEEKNSCALLKAATVFGACEWLLFMFTA 150
                 *************444........455789*******************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (175 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       614  (0.0342462); expected 358.6 (0.02)
Passed bias filter:                      309  (0.0172346); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.33s 00:00:00.84 Elapsed: 00:00:01.12
# Mc/sec: 472.24
//
Query:       EEA22136.1  [L=145]
Description: hypothetical protein PMAA_059160 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (145 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       734  (0.0409393); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.53u 0.31s 00:00:00.84 Elapsed: 00:00:00.53
# Mc/sec: 824.11
//
Query:       EEA22137.1  [L=152]
Description: hypothetical protein PMAA_059170 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (152 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       399  (0.0222544); expected 358.6 (0.02)
Passed bias filter:                      266  (0.0148363); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.39u 0.26s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 1111.53
//
Query:       EEA22138.1  [L=129]
Description: hypothetical protein PMAA_059180 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (129 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       930  (0.0518713); expected 358.6 (0.02)
Passed bias filter:                      645  (0.0359752); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 865.31
//
Query:       EEA22139.1  [L=216]
Description: peroxisomal membrane protein (PmpP24), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.4e-12   45.6   1.0    1.2e-11   45.0   1.0    1.3  1  Tim17     Tim17/Tim22/Tim23/Pmp24 family


Domain annotation for each model (and alignments):
>> Tim17  Tim17/Tim22/Tim23/Pmp24 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.0   1.0   6.6e-16   1.2e-11      14     111 .]      24     130 ..      20     130 .. 0.88

  Alignments for each domain:
  == domain 1  score: 45.0 bits;  conditional E-value: 6.6e-16
       Tim17  14 llGavfglvkgsrradtpapsker........lreglrsvgkrgpslGknfgvvgglysgiecaleklR..g.kediwnsvaAGaltGal.lragpqaa 100
                 l+ a++g+v+g++ +++  ++ ++        +re+++ v k++++++ n++ ++++y+++  a+++l   g ke ++++++AG+l+G++ + ++ +++
  EEA22139.1  24 LKAARNGAVYGAKVRFP--HALVMvflfrsgtFREKVKLVLKATRQHASNLARFAVIYKSAMFAMKYLNptGpKEGPYDTFFAGLLGGYVvF-GRNSGS 119
                 6789999*****99997..4444455777777***********************************875535*****************56.999*** PP

       Tim17 101 avgaiggaafs 111
                 ++++i++++f+
  EEA22139.1 120 VSQQIVIYVFA 130
                 *********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (216 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       392  (0.021864); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.25s 00:00:00.72 Elapsed: 00:00:00.44
# Mc/sec: 1487.23
//
Query:       EEA22140.1  [L=358]
Description: ribosome biogenesis protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.5e-33  114.3   0.0      1e-32  113.8   0.0    1.2  1  Brix      Brix domain
  ------ inclusion threshold ------
       0.11   13.2   0.4       0.29   11.8   0.4    1.8  1  NUP50     NUP50 (Nucleoporin 50 kDa)


Domain annotation for each model (and alignments):
>> Brix  Brix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.8   0.0   1.1e-36     1e-32       1     192 [.      35     238 ..      35     239 .. 0.92

  Alignments for each domain:
  == domain 1  score: 113.8 bits;  conditional E-value: 1.1e-36
                 BTT--HHHHHHHHHHHHHCTTSEEEEEEECT..-TTTHHHHHHH-HHHHHHHHHCTCSEEEEEE..S.STTE............EEEEEEEECECTGGG CS
        Brix   1 grktssrlrqllkdlrslmkphtasflkrns..nklkdlvelagvthlellsekndcslfvfelskk.rPng............ptlefkvenyslmkd 84 
                 g+k++  l+ llk ++ l +p+++ f+k+n+  +++++      ++++e+l++kn+c+++v ++s+k rPn+             ++e+ ++     + 
  EEA22140.1  35 GTKCPLPLNTLLKTIHGLTNPNSVLFHKKNDnvHPFES------TESIEFLADKNECGIVVYGSSNKkRPNCltlvriynkkvlEMFELLLLPPADGEA 127
                 5788999*********************66668*****......99***************************99999999999999999998888888 PP

                 STTTS....TS-TT---EEEEES........HHHHHHHHHHHHHH.....SEEEG..-B-GG-SEEEEEEES.CCTT.T.ECEEEEEEEEEEE..STTT CS
        Brix  85 lkkak....ktefgsrPllvfng.......kenfkllksllqdlFr...vpkislkspklsglrrvvlftaaenqet.d.ktisfRhYaiklkksgkkl 167
                 ++  +    ++e+g +P+++f+g       ++ + ++ks+l+d+F+   ++ki++     +gl++++++ a+e +e+   ++i++R+Y+i++++sg+kl
  EEA22140.1 128 IPAPSalklEIEVGIKPMILFAGsiwedatSNTYAMVKSVLLDMFKgeeTDKIDV-----EGLQYIMMVGAEEPAEAgLmPVIHLRWYKIRTRRSGHKL 221
                 887778899*****************99988889************999999999.....9*********887666652579***************** PP

                 TECT..T..EEEEEEESEEEEEEEE CS
        Brix 168 pnlekekkerveLeEiGPrfdLklr 192
                 p        rveL+E+GP+fd+++ 
  EEA22140.1 222 P--------RVELDEVGPKFDFRIG 238
                 *........*************986 PP

>> NUP50  NUP50 (Nucleoporin 50 kDa)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.4   3.3e-05      0.29      34      55 ..     288     311 ..     241     336 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3.3e-05
                 HHHHCS-S-S---TTT--XXX..X CS
       NUP50  34 evLakRkIkkakrrvsssaps..e 55 
                 + L++Rk+k++krr +  + s  e
  EEA22140.1 288 SNLQTRKMKGLKRRAGVDTDSedE 311
                 689************666654331 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (358 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       445  (0.0248201); expected 358.6 (0.02)
Passed bias filter:                      314  (0.0175135); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 2413.05
//
Query:       EEA22141.1  [L=519]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (519 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1520  (0.0847788); expected 358.6 (0.02)
Passed bias filter:                      302  (0.0168442); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.94u 0.32s 00:00:01.26 Elapsed: 00:00:00.48
# Mc/sec: 3253.43
//
Query:       EEA22142.1  [L=301]
Description: ribonuclease P complex subunit Pop2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.1e-66  223.5   0.0      3e-66  223.0   0.0    1.2  1  RNase_P_p30  RNase P subunit p30


Domain annotation for each model (and alignments):
>> RNase_P_p30  RNase P subunit p30
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  223.0   0.0   1.7e-70     3e-66       1     214 [.       3     209 ..       3     210 .. 0.94

  Alignments for each domain:
  == domain 1  score: 223.0 bits;  conditional E-value: 1.7e-70
                  EEEEE-SH.........HHHHHHHHH-SEEEEEEEEEESS---HHHHH.......HHHHHHHH..HHSSEEEEEEES-H.HHHHHHHHH--EEEEE-- CS
  RNase_P_p30   1 ydlnipwpsddskkksrtiktlaelgytgvainftveaekekkpnasepikeelkelkkelsglkllsRvtlvvsdpsklqrlskvrqkfdllavrPt 98 
                  ydln+p++ dd + ++ t++ lae gyt+va+++t++   +k p +      + + ++++ ++l+ll+R++lv+sdps+  r +++   f ++avrP+
   EEA22142.1   3 YDLNVPYSADDAQLTN-TLNFLAEVGYTTVALSQTMS---GKLPPNLA----APQLPSNAPKSLTLLTRLNLVLSDPSQSYRMANLIPLFSIVAVRPM 92 
                  8**********88876.********************...77777777....34455555556***************99****************** PP

                  SHHHHHHHHHT.T-SEEE-TTTTSSS-S--HHHHHHHHHHT-EEEEESHHHHHS-H.HHHHHHHHHHHHHHHHHHH--EEEE--BSSGGG---HHHHH CS
  RNase_P_p30  99 tekalraacenldvDiisidltsrlpfglkhktiraAvergvafEinyspllrdsg.laRrnfisnarkllrltrgkgvviSSgAesplelRnpydii 195
                  +ek l  ac+nld+D+is+dl+ rlpf++k+kt+++A++rgv+fEi+ysp + +sg +aRrn+i na++l+r+trg+g++iSS+A+++l +R+p+d++
   EEA22142.1  93 NEKSLLNACTNLDCDLISLDLSVRLPFHFKFKTVSSAISRGVRFEICYSPGITGSGlEARRNLIGNAMSLIRATRGRGIIISSEAKRALAIRAPMDVV 190
                  ********************************************************99**************************************** PP

                  HHHHHHT--HHHHHHTTTH CS
  RNase_P_p30 196 nLlktlGLeedrakeavse 214
                  nL++++GL+ +r kea+ e
   EEA22142.1 191 NLACVWGLSHERGKEAICE 209
                  ****************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (301 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       829  (0.0462379); expected 358.6 (0.02)
Passed bias filter:                      483  (0.0269396); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 1963.53
//
Query:       EEA22143.1  [L=335]
Description: casein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-64  218.3   0.2    1.3e-64  218.1   0.2    1.0  1  Pkinase         Protein kinase domain
    2.6e-19   69.5   0.0    3.8e-19   69.0   0.0    1.2  1  Pkinase_Tyr     Protein tyrosine kinase
    9.5e-08   32.3   0.0      6e-05   23.1   0.2    2.4  2  APH             Phosphotransferase enzyme family
     0.0036   16.2   0.0     0.0069   15.2   0.0    1.4  1  Pkinase_fungal  Fungal protein kinase
     0.0075   15.6   0.0      0.012   15.0   0.0    1.3  1  Kinase-like     Kinase-like
  ------ inclusion threshold ------
      0.024   14.0   0.1      0.039   13.3   0.1    1.4  1  Kdo             Lipopolysaccharide kinase (Kdo/WaaP) family
      0.066   12.8   0.1      0.066   12.8   0.1    2.0  3  Choline_kinase  Choline/ethanolamine kinase


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  218.1   0.2   5.1e-68   1.3e-64       1     264 []      32     317 ..      32     317 .. 0.91

  Alignments for each domain:
  == domain 1  score: 218.1 bits;  conditional E-value: 5.1e-68
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHS.CTTB--EEEEEEESSEEE..EEEE--TTEBHHHHHHHHSS-- CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklk.hpnivrlyevfeekdely..lvleyveggeladllerkgsls 96 
                 ye+++k+G+G++++V+++++  + ++ ++K++k  k+kk k     rEikil++l+  pn+v l++v++++++ +  lv+e+v+++++ +l+ r   + 
  EEA22143.1  32 YEVVRKIGRGKYSEVFEGINVVNYQKCVIKVLKPVKKKKIK-----REIKILQNLSgGPNVVALLDVVRDNQSKTpsLVFEFVNNTDFRTLYPR---FV 122
                 7899*****************************99988855.....7***********************6665555***************86...** PP

                 HHHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEE.TTTEEEE-SGTTSEESSSSCSBCTTTSCGGGS-HHHH.TTSCBSHHHHHHHHHHHHHHHHHS CS
     Pkinase  97 eeeakkiakqilegleylHskgiiHrDlKpeNiLid.ekgelKitDFGlakelessskltsfvgtseYlAPEvl.keneyskkvDvWslGvilyelltg 193
                 + +++ ++ ++l++l+++Hskgi+HrD+Kp+N++id e+++l+++D+Gla+ ++++++++ +v+++++  PE+l + +ey+ + D+WslG ++++++++
  EEA22143.1 123 DYDVRYYIFELLKALDFCHSKGIMHRDVKPHNVMIDhENRKLRLIDWGLAEFYHKGTEYNVRVASRYFKGPELLvDFQEYDYSLDMWSLGAMFASMIFR 221
                 ************************************88888*********************************888********************** PP

                 S-STTTSSHHHHHHHHHHTHHHHHHHCT.SHH...HHHTTS..............................-HHHHHHHHHHT-SSGCCSTTHHHHHTS CS
     Pkinase 194 kppfsgekgkekvekeldqlekilkilg.etkeklpeasei..............................seeakdllkkllkkdpkkRltaeellqh 261
                 k+pf +        +++dql+ki+k+lg e+ +++  +++i                              s+ea+d+l+kllk+d+ +Rlta+e+++h
  EEA22143.1 222 KEPFFH------GISNADQLVKIAKVLGtEELFEYLDKYDIeldsqyddilsrypkkpwhsfvnaenqrfvSNEAIDFLDKLLKYDHAERLTAQEAMAH 314
                 *****3......34578999999999984222333333334777777999************************************************* PP

                 GGG CS
     Pkinase 262 pyl 264
                 py+
  EEA22143.1 315 PYF 317
                 **8 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.0   0.0   1.5e-22   3.8e-19       3     215 ..      34     235 ..      32     246 .. 0.84

  Alignments for each domain:
  == domain 1  score: 69.0 bits;  conditional E-value: 1.5e-22
                  EEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS.-BTTB--EEEEEE..SSSSEEEEEE--TTEBHHHHHHHTCT CS
  Pkinase_Tyr   3 lgkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkkl.khpnivkllgvct..keepllivteyvkgGdLlkfLrkkek 97 
                  + +k+G+G++++V+eg        + +k+++K+lk  +++    ++ +e+ki+++l   pn+v+ll v+   ++++  +v+e+v++ d+++   +   
   EEA22143.1  34 VVRKIGRGKYSEVFEGINV----VNYQKCVIKVLKPVKKK----KIKREIKILQNLsGGPNVVALLDVVRdnQSKTPSLVFEFVNNTDFRTLYPR--- 120
                  6799*************99....88999******776555....599*********999***********7666779***********9986555... PP

                  TTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEE.TTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSE.EEHHHHHHHHHH CS
  Pkinase_Tyr  98 ekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlse.nkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekk.ftsksDvWsfGv 193
                    +   d+  +++++ k++++ +sk ++Hrd+   Nv++++ n++ ++ D GLa+  +k  ey+++  ++    +  pE l + + +  + D+Ws G 
   EEA22143.1 121 --FVDYDVRYYIFELLKALDFCHSKGIMHRDVKPHNVMIDHeNRKLRLIDWGLAEFYHKGTEYNVRVASR---YFKGPELLVDFQeYDYSLDMWSLGA 213
                  ..5667888999***************************973669**********997777776655443...4679**987755499999******9 PP

                  HHHHHHTTSSGTTTTSHHHHHH CS
  Pkinase_Tyr 194 llwEiftlgespypglkneevl 215
                  +   ++   e  ++g++n++ l
   EEA22143.1 214 MFASMIFRKEPFFHGISNADQL 235
                  9998888777667777776655 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.8   0.0    0.0022       5.7      21      84 ..      56     116 ..      34     138 .. 0.73
   2 !   23.1   0.2   2.3e-08     6e-05     165     197 ..     142     173 ..     130     201 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0022
                 --EEEEEE-TTS-HHHHHHHHHHHHHHHHTT-B--B-CTTBS-EEETTEEEEEEE----EE-SS CS
         APH  21 gryvlrrnpparaaeeirrevallrlLakagvpvPevlagdtddeeigllfalieyvpgrsllr 84 
                 ++ v ++  p   + +i re ++l++L++  + v ++l+   d +++ ++++++e+v  +++++
  EEA22143.1  56 QKCVIKVLKPV-KKKKIKREIKILQNLSGG-PNVVALLDVVRD-NQSKTPSLVFEFVNNTDFRT 116
                 56788888888.999*************99.558899996544.55555999999998887776 PP

  == domain 2  score: 23.1 bits;  conditional E-value: 2.3e-08
                 -EEEE-SS-SGGGEEEC..TTEEEEE---TT-E CS
         APH 165 ptvllHgDlhpgNllvdpddgrvtGviDfedag 197
                 +++++H+D +p+N+++d ++ ++  +iD+++a 
  EEA22143.1 142 SKGIMHRDVKPHNVMIDHENRKL-RLIDWGLAE 173
                 689**************777776.9*****985 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   2.7e-06    0.0069     325     367 ..     142     180 ..     132     210 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 2.7e-06
  Pkinase_fungal 325 kagiLHrDiSenNilitdskkegerkglLiDLDlakelsddss 367
                      +gi+HrD+  +N++i     +++rk  LiD  la  +++ ++
      EEA22143.1 142 SKGIMHRDVKPHNVMID----HENRKLRLIDWGLAEFYHKGTE 180
                     79**************9....5688999***999998886443 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   4.5e-06     0.012     157     250 ..     137     225 ..      86     242 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 4.5e-06
  Kinase-like 157 aanLqakglvhgkftvdnllldekg...glmlggftaLvragtkvvlsevekgfaPpEllgsrggytrknktkmthkldaWqlGlviyriwclklPl 250
                      ++kg++h +++++n++ d++    +l+  g+ + + +gt++ +    + f+ pEll     ++     ++ ++ld W lG+   ++  +k P+
   EEA22143.1 137 LDFCHSKGIMHRDVKPHNVMIDHENrklRLIDWGLAEFYHKGTEYNVRVASRYFKGPELLVD---FQ-----EYDYSLDMWSLGAMFASMIFRKEPF 225
                  555689***************976411145556889**********99999*********99...44.....4889*********998888888776 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.1   1.5e-05     0.039     135     166 ..     141     169 ..      94     183 .. 0.93

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.5e-05
         Kdo 135 hragvnHadlyaknillqqeeeeeaeiwliDl 166
                 h+ g++H+d+ ++n++++ e+   +++ liD 
  EEA22143.1 141 HSKGIMHRDVKPHNVMIDHEN---RKLRLIDW 169
                 9*****************997...99999995 PP

>> Choline_kinase  Choline/ethanolamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       2.4   6.1e+03      97     138 ..      29      66 ..      21      76 .. 0.63
   2 ?   12.8   0.1   2.6e-05     0.066     148     174 ..     146     172 ..     120     181 .. 0.81
   3 ?   -2.9   0.1       1.6   4.2e+03     168     193 ..     196     221 ..     194     235 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 2.4
                     HHHHHHCCS.TT..ECHHGGCCHCCCTHHHHHHHHHTHHHHH CS
  Choline_kinase  97 mqkwllnkeaqtkakkekkkkqlklinledlekeleklekll 138
                     ++++    e+ +k  + k+++ ++ in+ +++k + k+ k +
      EEA22143.1  29 LENY----EVVRKIGRGKYSEVFEGINVVNYQKCVIKVLKPV 66 
                     4444....6666666777777777777777777776665555 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 2.6e-05
                     E-S--SGGGEEE.-CTTEEEE--GTT- CS
  Choline_kinase 148 cHnDlqegNillnkeekklvlIDFEYa 174
                      H D+ ++N++ ++e++kl lID+  a
      EEA22143.1 146 MHRDVKPHNVMIDHENRKLRLIDWGLA 172
                     378*********************666 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 1.6
                     E--GTT-EEEEHHHHHHHHHHHTTEE CS
  Choline_kinase 168 lIDFEYagynyrgfDlanhfiEwagd 193
                     l+DF    y+  ++ l+ +f+ + + 
      EEA22143.1 196 LVDFQEYDYSLDMWSLGAMFASMIFR 221
                     78885558999999999999999882 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (335 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       638  (0.0355848); expected 358.6 (0.02)
Passed bias filter:                      504  (0.0281109); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 2133.85
//
Query:       EEA22144.1  [L=1057]
Description: valyl-tRNA synthetase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.2e-216  720.7   0.5   1.2e-216  720.7   0.5    2.3  2  tRNA-synt_1      tRNA synthetases class I (I, L, M and V)
    6.8e-34  117.0   1.7    6.8e-34  117.0   1.7    2.0  2  Anticodon_1      Anticodon-binding domain of tRNA
    2.2e-15   56.3   3.6    6.2e-07   28.5   0.1    4.4  4  tRNA-synt_1g     tRNA synthetases class I (M)
    2.8e-09   36.7   2.1    2.1e-06   27.4   0.0    2.9  3  tRNA-synt_1_2    Leucyl-tRNA synthetase, Domain 2
     0.0039   16.6   0.0        1.1    8.6   0.0    2.5  2  tRNA-synt_1e     tRNA synthetases class I (C) catalytic domai
     0.0045   16.7   1.4     0.0045   16.7   1.4    2.0  2  PRP3             pre-mRNA processing factor 3 (PRP3)
     0.0085   16.4   5.9     0.0085   16.4   5.9    3.2  3  Val_tRNA-synt_C  Valyl tRNA synthetase tRNA binding arm
  ------ inclusion threshold ------
      0.086   12.6   0.1        0.2   11.5   0.1    1.6  1  DUF4028          Protein of unknown function (DUF4028)


Domain annotation for each model (and alignments):
>> tRNA-synt_1  tRNA synthetases class I (I, L, M and V)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -6.3   2.4         7   1.6e+04     445     488 ..      55      98 ..      48      98 .. 0.67
   2 !  720.7   0.5  5.2e-220  1.2e-216       2     602 .]     106     728 ..     105     728 .. 0.99

  Alignments for each domain:
  == domain 1  score: -6.3 bits;  conditional E-value: 7
  tRNA-synt_1 445 reelkelvagreeeeaekkalekeakdklkkekgelekdedvlD 488
                  re  k  +a++++e+++k+a++k a+ k +k+++ +ek +d  D
   EEA22144.1  55 RERRKAEKAKKFAEKQAKAAAAKPAQPKAEKKEKVIEKTTDAYD 98 
                  34455556667777777888888888888888888888888765 PP

  == domain 2  score: 720.7 bits;  conditional E-value: 5.2e-220
  tRNA-synt_1   2 lyekWeeedvfkkelekeke.kke..filvdgPPyvtGslHiGhalaktlkdivirykrmkGkevlyvpGwDhaGlaieakvekklgakekkerkklg 96 
                  +ye+We++++fk++++++ e k++  f+++ +PP+vtG+lH+Ghal  +l+d+++ry+rmkGk++ +vpG+DhaG++++++vek+l++++k++r++lg
   EEA22144.1 106 RYEWWEKKGLFKPHFDANGEvKPDgvFSMTCPPPNVTGALHMGHALMVALQDTMTRYYRMKGKTTVWVPGTDHAGISTQSVVEKMLWKEKKQTRHDLG 203
                  69****************99777688************************************************************************ PP

  tRNA-synt_1  97 reefrekvrewkaeyaeeirkqvkrlGvsvDfdreylTldkeleeavkevfvrladkgliyrgkklvnwstklktalselEveykdkk.......... 184
                  r ef + +++wk++y+ +i  ++k + +s+D++re++T+++++++av+e+f+rl+++g iyr+++lvnw+ +l+t+ls+lEv+++d++          
   EEA22144.1 204 RPEFLKLTQDWKDRYQGSILTSLKAMAASLDWSREAFTMNPNFSAAVTETFCRLHEEGTIYRANRLVNWCCALNTSLSNLEVQNQDVSgrtlldvpgy 301
                  ************************************************************************************************** PP

  tRNA-synt_1 185 ......dalihvafpladkeevklviaTTtPeTllgdtavavnpeldyvitkeklilaeallkslvkkesekkiledergkeLegkevelplvnrkip 276
                        ++l+h+ +++++  e +++iaTT+PeT+lgdt++av+p+                               d+r+++++gk++++p+v+r +p
   EEA22144.1 302 ekkvefGVLTHFCYEIEGTGE-RIEIATTRPETMLGDTGIAVHPD-------------------------------DKRYQHIIGKKAKHPFVDRLLP 367
                  ******************999.***********************...............................9********************* PP

  tRNA-synt_1 277 iiaddyvdkeaGtGvVkiaPahdedDyevgkkynlevinildedgtlteeaaefeglkvfdarkkvveelkekglllkaekiehsvpfcerskkpiiy 374
                  i+ad  v +++GtG+Vk++Pahd++Dy+ gk+++le+++il++dgtl+++++ f+g+k+fdar++v+e+lke gl++k e++ + +p ce+sk++i++
   EEA22144.1 368 IVADSTVAMDFGTGAVKLTPAHDFNDYARGKQHGLEFVSILNDDGTLKDNCGPFSGMKRFDARYAVIEKLKEAGLYVKWENNPMVIPRCEKSKDIIEP 465
                  ************************************************************************************************** PP

  tRNA-synt_1 375 rateqWfvrvkeladaalkave..kvqfvpkskekryaswleniqdWciSRqrwWGhriplfvsketeevvvreelkelvagreeeeaekkalekeak 470
                   +++qW+++++++a+aa++ave  +++++p s+ek++++w++niqdWciSRq+wWGh+ p++  + +++v  + + + +v gr+eeea++ka++k   
   EEA22144.1 466 VLKPQWWMKMDDMAKAAMEAVEkkEITISPLSAEKNFFHWMRNIQDWCISRQLWWGHQAPAWLVQIEGQVADDGDSNLWVSGRSEEEAQAKAAAKFPG 563
                  *********************98899**********************************************9************************* PP

  tRNA-synt_1 471 dklkkekgelekdedvlDvWFsSgswpfstlgypeedteelkkffpadmlleGlDiirgWvarlillslaltgsePfkevlvhglvrdeeGrKmSKsl 568
                  +k+     +l++dedvlD+WFsSg+wpf+tlg+p++++++++k fp+++l++G+Di+++Wvar+i+lsl+ltg++Pfkev++h+l+rd+eGrKmSKsl
   EEA22144.1 564 QKF-----TLKRDEDVLDTWFSSGLWPFATLGWPNTESHDYQKLFPTSTLETGWDILFFWVARMIMLSLKLTGKVPFKEVYCHSLIRDSEGRKMSKSL 656
                  999.....****************************************************************************************** PP

  tRNA-synt_1 569 gNvidpldvik.....................................kygadalRltli.lsdvgrdinls 602
                  gNvidpldv +                                     ++gadalR++l+ +++ g di+++
   EEA22144.1 657 GNVIDPLDVQRgitldalheklkqgnlaekeigvatkyqkkafpkgipECGADALRMALVsYTTGGGDIAFD 728
                  *********99*************************************************9*******9875 PP

>> Anticodon_1  Anticodon-binding domain of tRNA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.0   1.7     3e-37   6.8e-34       1     148 [.     773     922 ..     773     927 .. 0.92
   2 ?   -2.6   0.1       2.2   4.9e+03      43      73 ..     979    1005 ..     976    1033 .. 0.54

  Alignments for each domain:
  == domain 1  score: 117.0 bits;  conditional E-value: 3e-37
  Anticodon_1   1 drwilselnklvkevteayeeyrfnkaasalyeffwndlcdwylelvkprlysesaedkra.aqevllevletllrllaPfmPfitEelwqr.eeeel 96 
                  +rwil+++n ++ke+++a+e  +f+  as +y+ ++ +lcd+y+e +k+ l+s+ +++ ++ a+++l+++le  l l++P+mP+itE+lwqr  +++ 
   EEA22144.1 773 ERWILQKFNTAAKEINNAIETREFSVSASTAYQYIYSQLCDVYIENSKSLLQSDAPAEVQEsAKQTLYTALEGSLLLIHPIMPYITEDLWQRlPRRQG 870
                  69*************************************************99887666777******************************844455 PP

  Anticodon_1  97 gkkesimlaewpe.kaeelekeleeeevellkeivkairklrselkikpssel 148
                  +k esim+a +pe +ae+ ++++ e+++el+ ++ kair++ +++++k +s+l
   EEA22144.1 871 DKTESIMVARFPEyNAEFDDEAA-EKAYELVLDTSKAIRSILAQYDVKEKSDL 922
                  778*********98887777777.99**********************99985 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 2.2
  Anticodon_1   43 ylelvkprlysesaedkraaqevllevletl 73  
                   yl+++k+    + ++ k    ++l + l+ +
   EEA22144.1  979 YLKVSKQVALEQAEKAK----ANLQKTLDLV 1005
                   66666655544333222....3333333333 PP

>> tRNA-synt_1g  tRNA synthetases class I (M)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.5   0.1   2.8e-10   6.2e-07       3      58 ..     134     189 ..     132     288 .. 0.74
   2 !   14.7   0.5   4.2e-06    0.0094     165     238 ..     452     525 ..     440     535 .. 0.83
   3 !    9.3   0.0   0.00018      0.41     313     350 ..     636     674 ..     611     690 .. 0.77
   4 ?   -2.4   0.0      0.66   1.5e+03      21      84 ..     855     917 ..     849     953 .. 0.70

  Alignments for each domain:
  == domain 1  score: 28.5 bits;  conditional E-value: 2.8e-10
                   EEE--B--SS---HHHHHHHHHHHHHHHHHHHTT-EEEEEEEE---SHHHHHHHHH CS
  tRNA-synt_1g   3 vttalpYangklHlGhllevisaDifaRykrlrgeevlfvcgtDehGtpielkAek 58 
                   +t++ p ++g+lH+Gh+l v   D ++Ry r++g+ +++v gtD+ G+ ++   ek
    EEA22144.1 134 MTCPPPNVTGALHMGHALMVALQDTMTRYYRMKGKTTVWVPGTDHAGISTQSVVEK 189
                   69999*************9999*************************988765544 PP

  == domain 2  score: 14.7 bits;  conditional E-value: 4.2e-06
                   ............EEE.EEEEEE-GGGGHHHHHHHH.HH-TT.SHHHHHHHH.HHHHT----EE-ESS-SSS-EET CS
  tRNA-synt_1g 165 inpksaisgskpevketehlffklskfekklkewieeeeke.leenvkkivkewlkegLkdlaisrdldwGipvP 238
                   + p++  s++  e   + ++++k+++++k+  e +e++e +  + +++k   +w+++ ++d++isr+l wG + P
    EEA22144.1 452 VIPRCEKSKDIIEPVLKPQWWMKMDDMAKAAMEAVEKKEITiSPLSAEKNFFHWMRN-IQDWCISRQLWWGHQAP 525
                   5577777776554445589****************88888888888999999****9.*************9999 PP

  == domain 3  score: 9.3 bits;  conditional E-value: 0.00018
                   S-EEEE--EE.E--------------HHHHHHHH-HHHH CS
  tRNA-synt_1g 313 kkvvaheylt.vegkKlSkSrgvvvkakealerldadll 350
                   k+v+ h+ +   eg+K+SkS g+v+++ +++  ++ d+l
    EEA22144.1 636 KEVYCHSLIRdSEGRKMSKSLGNVIDPLDVQRGITLDAL 674
                   5666666664379*****************999999987 PP

  == domain 4  score: -2.4 bits;  conditional E-value: 0.66
                   HHHHHHHHHHHHHHTT-E..EEEEEEE---SHHHHHHHHHTTS-HHHHHHHHHHHHHHHHHHTT-- CS
  tRNA-synt_1g  21 evisaDifaRykrlrgee..vlfvcgtDehGtpielkAekegvtpeelvekvheeikelfkklnis 84 
                    +i  D + R  r +g++   ++v+   e+      +A+++   + elv +++++i++++++++++
    EEA22144.1 855 PYITEDLWQRLPRRQGDKteSIMVARFPEYNAEFDDEAAEK---AYELVLDTSKAIRSILAQYDVK 917
                   68999999999999987633688888888888888877775...4577777788888877777775 PP

>> tRNA-synt_1_2  Leucyl-tRNA synthetase, Domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.4   1.5       5.2   1.2e+04      53      81 ..      58      86 ..      47     104 .. 0.54
   2 !    8.7   0.0   0.00051       1.2      12      50 ..     313     351 ..     308     356 .. 0.85
   3 !   27.4   0.0   9.4e-10   2.1e-06      86     143 ..     354     411 ..     349     423 .. 0.91

  Alignments for each domain:
  == domain 1  score: -4.4 bits;  conditional E-value: 5.2
  tRNA-synt_1_2 53 ekkkelaafieevkkksesereletkeke 81
                   +k ++ ++f e+ +k   ++ ++ ++ek+
     EEA22144.1 58 RKAEKAKKFAEKQAKAAAAKPAQPKAEKK 86
                   44455556666555555555444444432 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.00051
  tRNA-synt_1_2  12 iefkveeseeklevfttrpdtlfGvtfvalapehplvek 50 
                    + +++e++ e++e+ ttrp+t+ G t +a+ p+ +  ++
     EEA22144.1 313 FCYEIEGTGERIEIATTRPETMLGDTGIAVHPDDKRYQH 351
                    557999**99*******************9999876655 PP

  == domain 3  score: 27.4 bits;  conditional E-value: 9.4e-10
  tRNA-synt_1_2  86 glkaihPitgekipiwvanyvlmeygtgavmavPahdqrDfeFakkynlpikqvikpe 143
                    g ka hP+ ++ +pi     v m++gtgav   Pahd +D++  k+++l++  +++ +
     EEA22144.1 354 GKKAKHPFVDRLLPIVADSTVAMDFGTGAVKLTPAHDFNDYARGKQHGLEFVSILNDD 411
                    7899***********************************************9998854 PP

>> tRNA-synt_1e  tRNA synthetases class I (C) catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.3   0.0    0.0047        11      12      51 ..     134     173 ..     125     325 .. 0.79
   2 !    8.6   0.0   0.00048       1.1     229     267 ..     626     665 ..     606     684 .. 0.75

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0047
                   EEEEEEBTTS--BHHHHHHHHHHHHHHHHHHHTT-EEEEE CS
  tRNA-synt_1e  12 lYvCGptvydashlGhaRslvafDilrrilqalgYdvqfv 51 
                   + +  p v  a h+Gha  +   D + r+ +++g    +v
    EEA22144.1 134 MTCPPPNVTGALHMGHALMVALQDTMTRYYRMKGKTTVWV 173
                   445567899**********************999877776 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.00048
                   HHHHSS.S--EEEEEEE--EEETTBE--TTTT---BHHHH CS
  tRNA-synt_1e 229 seaafd.kqlvkyflhnghlkiegekmsksLknfitikdv 267
                   s  +++  ++ + + h+ +   eg+kmsksL+n+i   dv
    EEA22144.1 626 SLKLTGkVPFKEVYCHSLIRDSEGRKMSKSLGNVIDPLDV 665
                   5555554677889999999999************976666 PP

>> PRP3  pre-mRNA processing factor 3 (PRP3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   1.4     2e-06    0.0045      24      90 ..      43     118 ..      30     168 .. 0.81
   2 ?   -2.3   1.2       1.3   2.9e+03     137     151 ..    1020    1034 ..     976    1050 .. 0.41

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 2e-06
        PRP3  24 ekGkfikqaeqlrekaqleelkkeiaeeakkaglesdlklaekapkk........eedevpndv.....EWWDavllkkk 90 
                 e+Gk+ +++e +re+++ e++kk  +++ak a+ ++++ +aek+ k         +    p  +     EWW ++ l k 
  EEA22144.1  43 EPGKVKSEKELERERRKAEKAKKFAEKQAKAAAAKPAQPKAEKKEKViekttdayD----PAAIeagryEWWEKKGLFKP 118
                 89***********************9999999888888888777776666644331....322255555***99877555 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1.3
        PRP3  137 akplyLTkkErKklR 151 
                  + ++   ++E+KklR
  EEA22144.1 1020 KVKIEVQEQEEKKLR 1034
                  122333334444444 PP

>> Val_tRNA-synt_C  Valyl tRNA synthetase tRNA binding arm
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -6.4   7.3         8   1.8e+04       2      31 ..      53      82 ..      50      95 .. 0.76
   2 ?   -1.7   0.0       1.7   3.7e+03      36      48 ..     827     839 ..     824     845 .. 0.80
   3 !   16.4   5.9   3.8e-06    0.0085      11      65 ..     996    1050 ..     988    1051 .. 0.90

  Alignments for each domain:
  == domain 1  score: -6.4 bits;  conditional E-value: 8
  Val_tRNA-synt_C  2 vekeraRLeKeLaklekeiervqkKLanpg 31
                     +e+er++ eK  + +ek+++ ++ K a p+
       EEA22144.1 53 LERERRKAEKAKKFAEKQAKAAAAKPAQPK 82
                     688888888888888888888888877776 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 1.7
  Val_tRNA-synt_C  36 APaeVVeeekakl 48 
                      APaeV e  k+ l
       EEA22144.1 827 APAEVQESAKQTL 839
                      9****99999877 PP

  == domain 3  score: 16.4 bits;  conditional E-value: 3.8e-06
  Val_tRNA-synt_C   11 KeLaklekeiervqkKLanpgFveKAPaeVVeeekaklaeleeqaeklkerLskL 65  
                        +L+k    + ++qk +++pg++eK+  eV e+e++kl ++e +a+ ++e++ +L
       EEA22144.1  996 ANLQKTLDLVSKIQKTMNTPGWREKVKIEVQEQEEKKLRDAEGEAALIEEQIRDL 1050
                       46888888999****************************************9988 PP

>> DUF4028  Protein of unknown function (DUF4028)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.1   8.9e-05       0.2      29      56 ..     192     219 ..     183     228 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 8.9e-05
     DUF4028  29 wfrkhenneklGrptfkevekdwkenke 56 
                 w  k++   +lGrp f ++ +dwk+  +
  EEA22144.1 192 WKEKKQTRHDLGRPEFLKLTQDWKDRYQ 219
                 88899999****************9755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1057 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1630  (0.0909142); expected 358.6 (0.02)
Passed bias filter:                      792  (0.0441742); expected 358.6 (0.02)
Passed Vit filter:                        83  (0.00462937); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 1.03u 0.32s 00:00:01.35 Elapsed: 00:00:00.52
# Mc/sec: 6118.11
//
Query:       EEA22145.1  [L=397]
Description: hypothetical protein PMAA_059250 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       995  (0.0554967); expected 358.6 (0.02)
Passed bias filter:                      453  (0.0252663); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.50
# Mc/sec: 2370.22
//
Query:       EEA22146.1  [L=547]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (547 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       279  (0.0155614); expected 358.6 (0.02)
Passed bias filter:                      250  (0.0139439); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 3874.50
//
Query:       EEA22147.1  [L=562]
Description: MFS alpha-glucoside transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      1e-84  285.0  26.1    1.2e-84  284.8  26.1    1.0  1  Sugar_tr    Sugar (and other) transporter
    7.1e-15   54.8  36.7    9.3e-11   41.2  28.9    2.2  2  MFS_1       Major Facilitator Superfamily
    0.00024   20.1   5.8    0.00024   20.1   5.8    2.3  2  MFS_1_like  MFS_1 like family


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  284.8  26.1     2e-88   1.2e-84       2     452 .]      67     524 ..      66     524 .. 0.92

  Alignments for each domain:
  == domain 1  score: 284.8 bits;  conditional E-value: 2e-88
                 HHHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTS CS
    Sugar_tr   2 alvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgkn 100
                  +v++ + +++gYd+ ++g  +++++f k++g+  s+++++  + +++ + + + vG+iiG ++ g++++rfG++ + +++ vl+++ +++ ++a+   
  EEA22147.1  67 SVVISSCIVMEGYDISLVGNLYAFPAFNKKYGVLGSDGTYQIPARWQSGLSNGAAVGEIIGLFINGYISERFGYRFTVMTCLVLLSAFTAIFFTAQ--- 162
                 578888889*****************************999999999999999*******************************************... PP

                 S-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHH.HTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHH CS
    Sugar_tr 101 svevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglgl.nktsnadgwrillglqlvpallllilllflPESPryl 198
                 +v+ l+++ +l+Gi++G++++l+ +y+sE++p +lR++l+ + + ++ +G++++ ++  ++ n++++ + +ri+ +lq++++l l+i++lf+PESP++l
  EEA22147.1 163 NVQTLLAAEILCGIPWGVFQTLTVTYASEVCPVSLRSYLTCYVNICWGIGQVIGVGVIKAMlNRSDQ-WAYRIPYALQWMWPLPLFIGVLFAPESPWWL 260
                 ********************************************************99999677777.******************************* PP

                 HHTT-HHHHHHHHHHHHHC.....HHHHHHHHHHHHHHHHHHH.......HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH. CS
    Sugar_tr 199 vekgkeeeakevlaklrge.....edadrelaeekdsleaeqeee..kaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsks. 289
                 v kg+ e+ak++l +l         da++ +a +++++  eq+ +  + +w++++++   ++r+ i+++++++q+l+G n++ +ys++++e++gls s 
  EEA22147.1 261 VRKGRVEDAKKSLLRLTSLnretdFDANETIAMMVHTTALEQKITsgSSYWDCFKGT--DLRRTEIVCMVWAIQNLSG-NSFSNYSTYFLEQAGLSSSd 356
                 ***************44443224466666666666666666555588999******9..79*****************.******************99 PP

                 .HHHHHHHHHHHHHHHHHHH.HHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS....CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHH CS
    Sugar_tr 290 .llvtiivgvvnfvatfvai.flvdrfGRRtllllGaagmaicfvilgivalllvaks.kaasivaivfialfialfalgwgpvpwvlvsElfpqsvRs 385
                  + + ++ + +n++ +f a+ ++   +GRRtl+l+G++g + +++++g    l+++++ +  + +   ++++++ ++++++g+v++ lv+E+++ ++  
  EEA22147.1 357 sYSFALGQYGINIIGVFGAWgLMAMGVGRRTLYLFGLCGLFSMLFVMG-FLGLVPEAHrTQGALATGSMMIIWALFYQISVGTVCYSLVAEISTRRLQI 454
                 999****************9456678*********************9.5555555554566666677889999************************* PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHCHHH...T-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 386 kalaiavavnwlanflisllfpiiteaig...ggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 k+  +  ++ +++ +++++l+p++++      g y ++++agl+ l i++++f +pe  grt+ e+++lf
  EEA22147.1 455 KTVVLGRNLYNIVGIITGVLTPYMLNPTAwdwGNYAGFFWAGLCFLCIVYTYFRIPEPTGRTFAELDALF 524
                 **************************999999**********************************9987 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.2  28.9   1.6e-14   9.3e-11      22     298 ..      92     415 ..      68     431 .. 0.62
   2 !   15.9  18.7     8e-07    0.0048      16     188 ..     339     523 ..     324     548 .. 0.74

  Alignments for each domain:
  == domain 1  score: 41.2 bits;  conditional E-value: 1.6e-14
       MFS_1  22 alaedlgispse......igl...lltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.sslwlllvlrvlqGlgagalfpagaali 110
                 a ++ +g+ +s       + +   l  + a+g +++ ++ G++s+rfG r +++++l+l++++ ++++f+ +++ +ll++ +l+G+  g++ ++ ++++
  EEA22147.1  92 AFNKKYGVLGSDgtyqipARWqsgLSNGAAVGEIIGLFINGYISERFGYRFTVMTCLVLLSAF-TAIFFTaQNVQTLLAAEILCGIPWGVFQTLTVTYA 189
                 55555553222222233344433355568999*******************666666666666.45554438888************************ PP

       MFS_1 111 adwfpkeergraigllsagfslGailgpllggllasslg...Wravfyilaivsllafvlfllllpeepperkrkspkeee.................. 188
                 +++ p + r+  + ++++++++G ++g ++  +++       +r ++ +     l +f+    +l++++++ + +++ + e                  
  EEA22147.1 190 SEVCPVSLRSYLTCYVNICWGIGQVIGVGVIKAMLNRSDqwaYRIPYALQWMWPLPLFI---GVLFAPESPWWLVRKGRVEdakksllrltslnretdf 285
                 ***************************77777777333333455555555555555555...6666666666666555555556666677777666666 PP

       MFS_1 189 ...............kgtgpaplvp.......awkallkdpvlw....illialllfffgfsglltllplylqevlgls...glllaglllallalvga 258
                                +        +        w  ++     +    i+ +++++  +  ++++ +++ +  e+ gls   ++  a++ +++  +++ 
  EEA22147.1 286 danetiammvhttalE--------QkitsgssYWDCFKGTD--LrrteIVCMVWAIQNLSGNSFSNYSTYF-LEQAGLSssdSYSFALGQYGINIIGV- 372
                 6666665555444331........02223333233333333..1323323333333333555566666665.*******9886666666777776666. PP

       MFS_1 259 ilallagrlsdrlgrrrrlllallllllaalglallavt.....s 298
                   +  +g ++  +grr+  l++l +l+ +++ + +l++      +
  EEA22147.1 373 --FGAWGLMAMGVGRRTLYLFGLCGLFSMLFVMGFLGLVpeahrT 415
                 ..4478888855666666666666666666666666555555541 PP

  == domain 2  score: 15.9 bits;  conditional E-value: 8e-07
       MFS_1  16 gpalplalaedlg.ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllf......a.......sslw.lllvlrvlqGlga 99 
                 +++++ +  e+ g +s ++++++l+ y++  +     +G ++  +Grr ++l+gl +++++l+++ f      a       +    ++++  ++  +  
  EEA22147.1 339 FSNYSTYFLEQAGlSSSDSYSFALGQYGINIIGVFGAWGLMAMGVGRRTLYLFGLCGLFSMLFVMGFlglvpeAhrtqgalA-TGsMMIIWALFYQIS- 435
                 33444433344443466779999999999888888899***********************555556565554233333332.444677777777776. PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafv.lfllllpeepperkrkspkeee 188
                   + +++++l+a++++++ + + + l    +++  i++ +l ++++    W +  y+  + + l+f+ +++ +++ ++p+ +++++ + +
  EEA22147.1 436 --VGTVCYSLVAEISTRRLQIKTVVLGRNLYNIVGIITGVLTPYMLNPTAWDWGNYAGFFWAGLCFLcIVYTYFRIPEPTGRTFAELDAL 523
                 ..69******************************************8888999866666666666666778*********9999988875 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   5.8     4e-08   0.00024     270     366 ..     121     216 ..     114     225 .. 0.90
   2 !    2.4   2.0    0.0096        58     227     310 ..     322     406 ..     286     474 .. 0.63

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 4e-08
  MFS_1_like 270 vvaeiplfffaeklleklGhvklliiallayilrfllyaiienawlvlpievLhgisfgllwaaaveyvskiapksleatgqgllsglyfglGralG 366
                 +v+ei+ +f++ ++ e++G ++ ++++l++  +   +  + +n+  +l +e+L gi  g++    v+y+s++ p sl++     ++ +++g+G+ +G
  EEA22147.1 121 AVGEIIGLFINGYISERFGYRFTVMTCLVLLSAFTAIFFTAQNVQTLLAAEILCGIPWGVFQTLTVTYASEVCPVSLRSY-LTCYVNICWGIGQVIG 216
                 799************************99988765555555************************************985.56789999******99 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.0096
  MFS_1_like 227 viifllvalilgmswgiienFlflYLkelgasntll.GslvalgvvaeiplfffaeklleklGhvklliiallayilrfllyaii 310
                   i+++v +i   s + + n+ + +L++ g s++   + ++    +  i +f     +   +G ++l +++l   +  +++++++
  EEA22147.1 322 TEIVCMVWAIQNLSGNSFSNYSTYFLEQAGLSSSDSySFALGQYGINIIGVFGAWGLMAMGVGRRTLYLFGLCGLFSMLFVMGFL 406
                 5577888888888888888888888888888765320222222223333333333333444555555555555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (562 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       602  (0.0335769); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.45
# Mc/sec: 3785.38
//
Query:       EEA22148.1  [L=667]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.098   12.6   0.6       0.25   11.3   0.6    1.6  1  SLATT_1   SMODS and SLOG-associating 2TM effector domain 1


Domain annotation for each model (and alignments):
>> SLATT_1  SMODS and SLOG-associating 2TM effector domain 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.6   1.4e-05      0.25      34      71 ..      34      71 ..      15      77 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 1.4e-05
     SLATT_1 34 lellalllaalrafgelsvdlvgvlaavaaallaWlel 71
                 +l++l+ aa  a+g+++ d++ ++aa+aaa+  +le 
  EEA22148.1 34 NQLAGLVQAATAAAGQADSDWATAAAAAAAAGHHHLEN 71
                68999**************************9999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (667 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1033  (0.0576162); expected 358.6 (0.02)
Passed bias filter:                      517  (0.028836); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.69u 0.28s 00:00:00.97 Elapsed: 00:00:00.45
# Mc/sec: 4418.77
//
Query:       EEA22149.1  [L=371]
Description: isopropanol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.5e-13   50.9   0.5    3.8e-13   49.5   0.2    1.8  2  ADH_zinc_N      Zinc-binding dehydrogenase
    2.3e-05   24.3   0.0    6.9e-05   22.7   0.0    1.9  1  ADH_N           Alcohol dehydrogenase GroES-like domain
     0.0032   16.8   1.9     0.0032   16.8   0.8    1.5  2  AlaDh_PNT_C     Alanine dehydrogenase/PNT, C-terminal domain
     0.0061   17.6   0.0       0.02   15.9   0.0    1.9  1  ADH_zinc_N_2    Zinc-binding dehydrogenase
  ------ inclusion threshold ------
      0.036   14.0   0.4      0.036   14.0   0.4    1.6  2  NAD_binding_10  NAD(P)H-binding
       0.13   11.8   0.2       0.36   10.4   0.3    1.7  2  NmrA            NmrA-like family
       0.14   12.2   0.0       0.28   11.3   0.0    1.4  1  DapB_N          Dihydrodipicolinate reductase, N-terminus


Domain annotation for each model (and alignments):
>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0       3.8   9.6e+03      83     109 ..      68      92 ..      67      94 .. 0.74
   2 !   49.5   0.2   1.5e-16   3.8e-13       3     127 ..     191     325 ..     191     328 .. 0.79

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 3.8
                 EEEEECSCTSSEEEEEHHHHHHTT-EE CS
  ADH_zinc_N  83 GrlvvvGggkgeeefdlrnlllkeksi 109
                 Gr+v vG   +  ++++++l++ +++i
  EEA22149.1  68 GRVVEVG--PDAVKLTPGQLVFCNITI 92 
                 8888888..455568888888888887 PP

  == domain 2  score: 49.5 bits;  conditional E-value: 1.5e-16
                 HHHHHHHHHHTT-EEEEEESSHHHHHHHHHT....TESEEEET.TTC.HHHHHHHHHTT.TSSEEEEEESSC....SHHHHHHHHHCEEEEEEEEECSC CS
  ADH_zinc_N   3 GlaavqlAkalGaeviavdsseeklelakkl....Gadeviny.kea.dlverikeltg.gegvdvvfecvG....sgatleaalkllkpgGrlvvvGg 90 
                 G aav++A a+Ga+v+a+ ++++ l+ ++++    G  +++   ++  +  e+ k + g ++g+dv+++++       + l aa+k+l+p Grlv++Gg
  EEA22149.1 191 GGAAVAVALAMGATVVAAGRNKDALAALESIhastGRLRTVALtEDPsSNAEAFKTAAGkPDGADVYIDFSPpamkGSSLLVAAVKALRPFGRLVIMGG 289
                 779**********************999998566664444444333334555666666669*********9733322456778999************9 PP

                 TSSEEEEEHHHHHHTT-EEEEE-SSCHHHHHHHHHHH CS
  ADH_zinc_N  91 gkgeeefdlrnlllkeksilGsllgslreefkealdl 127
                   ge +++  +++lk+++i+G +++s r+ + +++++
  EEA22149.1 290 HLGEISVSYLDIMLKSIRIQGRFMYS-RQHVLQLIQM 325
                 88878899999***************.7777778876 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   0.0   2.7e-08   6.9e-05       6      66 ..      33      93 ..      28     141 .. 0.77

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 2.7e-08
                EEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS--TT-EEEE-SEEE CS
       ADH_N  6 ikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkklkvGdrVvveplis 66
                +++  a +     ++l+g+++++ +lp+i+G   +G v+evgp+  kl+ G+ V+++++i 
  EEA22149.1 33 VRILGADVAPYMAEVLDGSRQYPLSLPMIPGNSSIGRVVEVGPDAVKLTPGQLVFCNITIL 93
                55555555555557778889***********************************998875 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.8   1.3e-06    0.0032      22      74 ..     172     225 ..     161     258 .. 0.77
   2 ?   -3.5   0.0       2.1   5.3e+03      13      37 ..     265     289 ..     260     308 .. 0.67

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 1.3e-06
                  EETCB---EEEEES..TSHHHHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTTCE CS
  AlaDh_PNT_C  22 gvpgvepakvlviG..gGvaGlqAiatakglgakVtvlDvrparleqleslgakf 74 
                   v  v+p++v+++    G  G +A+a+a ++ga+V++   ++++l  les++a++
   EEA22149.1 172 EVD-VKPGEVVIVApaTGRYGGAAVAVALAMGATVVAAGRNKDALAALESIHAST 225
                  444.89******954489********************************77653 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 2.1
                  CTSEEETTCEETCB--.-EEEEESTS CS
  AlaDh_PNT_C  13 fggkgtlaGgvpgvep.akvlviGgG 37 
                  ++g+ +l++ v+  +p ++ +++G G
   EEA22149.1 265 MKGSSLLVAAVKALRPfGRLVIMG-G 289
                  567777777787777734444444.4 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0     8e-06      0.02      12     129 ..     242     364 ..     230     368 .. 0.80

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 8e-06
                   TTHH.HHH-TT-EEEEEES-H....HHHH.HHHHHHEEEEEEEEE----.S-EEE-CHHHCTTT-EEEE--GGG...-.-HHHHHHHHHHHHHHH.. CS
  ADH_zinc_N_2  12 edfe.aatggegvDvvldtvg....gealleaslkvlpggGrlvsiggpplsaallkpakkrkgrsvkyeflfsmkasaqadileelaalieeGk.. 101
                   e+f+ aa +++g Dv +d       g +ll a++k+l++ Grlv +gg+     ++ +  + k+ +++  f+ s     +++   +l ++ e+G   
    EEA22149.1 242 EAFKtAAGKPDGADVYIDFSPpamkGSSLLVAAVKALRPFGRLVIMGGHLGEISVSYLDIMLKSIRIQGRFMYS-----RQH-VLQLIQMTESGVlk 332
                   556655556799******9889999999999999***999*******999888888888889889999999984.....677.8899*******955 PP

                   ....----EEEEEEGGGHHHHHHHHHSS--SS CS
  ADH_zinc_N_2 102 ....lrpvvdrvfpleeaaeAhrylesgrarG 129
                       l +  +++++le + +A+++ ++ + +G
    EEA22149.1 333 fgskLGINETQEYGLESIGDALQAAANLSGFG 364
                   55555566777799999999998876655555 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0       2.4   6.3e+03     171     181 ..      38      48 ..      23      49 .. 0.72
   2 ?   14.0   0.4   1.4e-05     0.036       2      69 ..     186     249 ..     186     291 .. 0.69

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 2.4
                     HHHHHHHHHHC CS
  NAD_binding_10 171 adVAdvlvavl 181
                     adVA ++++vl
      EEA22149.1  38 ADVAPYMAEVL 48 
                     78888888887 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 1.4e-05
                     TTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHHCTTTCEEEE--TT-CCHHHHHHTT-SEEEES-- CS
  NAD_binding_10   2 AtGkvGrllvkellargghevtalvRnpeklaeleaeeglevvegdvtdvedlaealkgadaVvsalg 69 
                     AtG+ G ++v+ +la g  +v+a  Rn++ la+le    +++ +g + +v+  ++  ++a+a  +a+g
      EEA22149.1 186 ATGRYGGAAVAVALAMG-ATVVAAGRNKDALAALE---SIHASTGRLRTVALTEDPSSNAEAFKTAAG 249
                     9***************5.9*************987...455555555555555555555555544444 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0         1   2.6e+03     181     200 ..      35      54 ..      20      65 .. 0.73
   2 ?   10.4   0.3   0.00014      0.36       1      65 [.     181     247 ..     181     277 .. 0.72

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 1
                 -HHHHHHHHHHHHHHHHHHH CS
        NmrA 181 daeeDiGafvikilkdprkl 200
                 +  +D++++++++l+  r++
  EEA22149.1  35 ILGADVAPYMAEVLDGSRQY 54 
                 45689999999999988877 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00014
                 EEESSTTSHHHHHHHHHHHHHT-EEEEEES-S-SHH.HHHHHHSTTEEE.ES-TT-HHHHHHHHTT- CS
        NmrA   1 IlviGaTGrqGksvvrallkaghkvralvRdtksel.akslkeaGvelv.kgdlddkeslvealkgv 65 
                 ++v  aTGr G++ v+++l+ g +v a  R+ +  + ++s+ ++   l   + ++d +s +ea+k++
  EEA22149.1 181 VIVAPATGRYGGAAVAVALAMGATVVAAGRNKDALAaLESIHASTGRLRtVALTEDPSSNAEAFKTA 247
                 57888**************************965430455554444444344455555555555554 PP

>> DapB_N  Dihydrodipicolinate reductase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00011      0.28       3      83 ..     181     269 ..     180     280 .. 0.55

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00011
                 EEEETTTSHHHHHHHHHHHHSTTEEEEEEEETTC..STTTTTBHH.......HHSSSS--S-BEBSSHHHHHHH-SEEEE-S-HHHHHHH CS
      DapB_N   3 vavvGasGrmGkevvkaveeaedlelvaavdrke..selegkdag.......ellglgklgvavtddleevlekadvliDFTtpeavlen 83 
                 v+v+ a+Gr G + v ++ +  ++++vaa  +k+   +le+  a+        l++  +++ + +++ +   + adv iDF+ p++  + 
  EEA22149.1 181 VIVAPATGRYGGAAVAVALA-MGATVVAAGRNKDalAALESIHAStgrlrtvALTEDPSSNAEAFKTAAGKPDGADVYIDFSPPAMKGSS 269
                 66777777777777776666.6666666655555222222222213333322333333555555555555555599******98876555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (371 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       399  (0.0222544); expected 358.6 (0.02)
Passed bias filter:                      334  (0.018629); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.49u 0.24s 00:00:00.73 Elapsed: 00:00:00.41
# Mc/sec: 2693.05
//
Query:       EEA22150.1  [L=423]
Description: sn-1,2-diacylglycerol cholinephosphotransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-15   57.6   0.2    1.6e-15   57.6   0.2    3.3  2  CDP-OH_P_transf  CDP-alcohol phosphatidyltransferase


Domain annotation for each model (and alignments):
>> CDP-OH_P_transf  CDP-alcohol phosphatidyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.6   0.2   9.1e-20   1.6e-15       1      66 []      56     131 ..      56     131 .. 0.85
   2 ?   -9.6  11.5         1   1.8e+04       6       6 ..     277     277 ..     136     392 .. 0.67

  Alignments for each domain:
  == domain 1  score: 57.6 bits;  conditional E-value: 9.1e-20
                      S-HHHHHHHHHHHHHHHHHGGGS-H.............HHHHHHHHHHHHHTTHHHHHHHHTT---HHHHHHHHHHH CS
  CDP-OH_P_transf   1 nlPnaiTllrlllsvlailllltyyp...........lvlailllliasltDalDGklARrlnqvstlGkllDslaD 66 
                      ++Pn++Tll+++++++++ ++ ++ p           + +a+ +++++++ D++DGk+ARr++++s lG+l+D+++D
       EEA22150.1  56 IAPNMVTLLGFFFIIINVAFVTIFVPdlvgpgptwvyYSFALGVWMYSTF-DNIDGKQARRTGTSSGLGELFDHGID 131
                      58****************98877777999999977655555555566666.*************777********99 PP

  == domain 2  score: -9.6 bits;  conditional E-value: 1
                      H CS
  CDP-OH_P_transf   6 i 6  
                      +
       EEA22150.1 277 V 277
                      1 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (423 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       787  (0.0438954); expected 358.6 (0.02)
Passed bias filter:                      345  (0.0192426); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2973.38
//
Query:       EEA22151.1  [L=1295]
Description: transcription initiation factor TFIID subunit TSM1/127kD, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.7e-06   28.3   0.0      0.089   13.0   0.0    2.5  2  Peptidase_M1_N  Peptidase M1 N-terminal domain


Domain annotation for each model (and alignments):
>> Peptidase_M1_N  Peptidase M1 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.5   0.1   6.9e-06      0.12       4      60 ..      26      83 ..      23     100 .. 0.88
   2 !   13.0   0.0     5e-06     0.089      83     153 ..     167     237 ..     108     255 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 6.9e-06
                    EEEEEEEEETTTTEEEEEEEEEEEES.S-ECEEEEEESSEEEECEEEEECTTCTCEEE CS
  Peptidase_M1_N  4 hYdldlkidlkektfkGsvtitlqlk.eatseivldakdlkiksvslsaevksesvki 60
                    h +l+l++dl++k++kG+ +it+ +   + ++i l+ ++ +ik+++++ ++++  + +
      EEA22151.1 26 HQKLELEVDLATKSLKGKTEITIHPHhREFRVIKLNFRQGQIKRLNINGKAATALKYT 83
                    778***********************999*************9999998777665555 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 5e-06
                     TCEEEEEEEEEEE-BSSSSEEEEEEEEETSCE..EEEEEEE-TTT.TGGGTS-B--STTSEBEEEEEEEEETTS CS
  Peptidase_M1_N  83 tskytLeieyegelndklaGlykstYtdkgek..kvvvvTqfeat.dARsafPCfDePsvKAtftisikapkee 153
                      + +t+ ie++    + ++Gl+    +d+g +   ++++T+     + + +fPC+D P v+  ++++ik p + 
      EEA22151.1 167 YTALTVYIEFTV--DNIREGLQFVG-VDSGDRryPHAYTTNSTGPgAGSCLFPCVDDPLVRCPWDVTIKCPCSL 237
                     556677777766..88888888544.3444332356677766655155679******************98765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1295 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       777  (0.0433376); expected 358.6 (0.02)
Passed bias filter:                      531  (0.0296168); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.87u 0.34s 00:00:01.21 Elapsed: 00:00:00.48
# Mc/sec: 8081.83
//
Query:       EEA22152.1  [L=77]
Description: small nuclear ribonucleoprotein SmG, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-22   78.4   0.5    2.6e-22   78.3   0.5    1.0  1  LSM       LSM domain


Domain annotation for each model (and alignments):
>> LSM  LSM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.3   0.5   1.5e-26   2.6e-22       2      66 ..       7      70 ..       6      71 .. 0.97

  Alignments for each domain:
  == domain 1  score: 78.3 bits;  conditional E-value: 1.5e-26
                HHHHTTTSEEEEEETTSEEEEEEEEEEETTSEEEEEEEEEEETTETEEEEEEEEEEEGGGEEEEE CS
         LSM  2 flkklinkkvtvelkngrelrGtLkgfDqfmNlvLedveetlkdkkekrklglvliRGnnivlis 66
                 lkk+++k++ v+l+++r+++G+L+g+D fmN+vL+d++e + d+  k +lg+v+iRGn++v+++
  EEA22152.1  7 ELKKYMEKRLFVQLNGNRKVIGILRGYDVFMNIVLDDAVEEKADG-GKDRLGMVVIRGNSVVMLE 70
                69*******************************************.****************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (77 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       308  (0.0171789); expected 358.6 (0.02)
Passed bias filter:                      269  (0.0150036); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.48
# Mc/sec: 485.42
//
Query:       EEA22153.1  [L=406]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (406 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1464  (0.0816554); expected 358.6 (0.02)
Passed bias filter:                      624  (0.0348039); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.60u 0.30s 00:00:00.89 Elapsed: 00:00:00.45
# Mc/sec: 2706.90
//
Query:       EEA22154.1  [L=555]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.6e-17   63.1  15.3    2.6e-17   63.1  15.3    2.1  2  LtrA             Bacterial low temperature requirement A prot


Domain annotation for each model (and alignments):
>> LtrA  Bacterial low temperature requirement A protein (LtrA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.1  15.3   1.5e-21   2.6e-17       2     272 ..      53     336 ..      52     362 .. 0.75
   2 !    2.6   3.3    0.0037        66     251     315 ..     466     531 ..     434     554 .. 0.65

  Alignments for each domain:
  == domain 1  score: 63.1 bits;  conditional E-value: 1.5e-21
        LtrA   2 vswlELFFDLvfVvavtqlthalahdltge..gllrflllffavwwaWvgftwlanrfdtddvvvrllllvqmaavlvlalsipeafeerg.......l 91 
                 +s++ELF+D   V+ v++l+   a++   +  ++  ++  + ++w +W + t+l  rf  d+++ r+  +vq+ a++ +a + ++  ++ +        
  EEA22154.1  53 ASPIELFYD---VFLVANLATFSATHEINNvtAVWSYVGFVGIIWFTWLQVTLLDLRFSRDSIFERTCKVVQLSAMIGFASAGSRFSSQIKdenvwafK 148
                 89*******...55566655543333333234899********************************************99988877766688898777 PP

        LtrA  92 vfalayvvmrlvlvlqylraaradpklsarrlarvyaagllisavlwlagallpgs.........arlvlwlvalliel.llvPllarkrt..tpvhae 178
                  + +     r++l+lqy + + + +++  r++ r +++ + + +v  +  +++ +            +++w+ +++ e  +   ++  ++t   +++  
  EEA22154.1 149 SLSILLSGSRFMLALQYTINLWFIREK-LRATGRGMFVIIGVHTVTGISYLIVRQMfrtfkpsepHIWIVWFGLFVFESvM--VITISNYTpgIELDDT 244
                 7778888899*******9977777654.57777777777777777766666655555555665543333444444445433..3333344345****** PP

        LtrA 179 HlaERygLfvIIaLGEsvva....lgaglseqelsvevllaa..vlglvlaaalwwlYFdv.daaaaehaltsarrarlarsaygylhllivagiilla 270
                 Hl+ R+gL+++I++GE v++    +++++++ +++++ ll +  v+++v  ++lw  Y+d  +++           ++l +++++ lh+++ + iil +
  EEA22154.1 245 HLTTRMGLLTLIIIGEHVISvtriVNKMIAGGGWTFASLLHVmgVVTTVPKYLLWHSYYDIsPRQS---------YGKLRQQIWTHLHFPFHMCIILSS 334
                 ********************77766777777779888877665566777779*********33322.........34566799*************987 PP

        LtrA 271 vg 272
                  +
  EEA22154.1 335 EA 336
                 65 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.0037
        LtrA 251 arsaygylhllivagiillavglelllahpeelldlaaalllfggv..alfllgllllkrvllgsvs 315
                    a+ y+++++++g+++l  ++  +l + +++ ++++a+++   +  a+ l++++++ +    + +
  EEA22154.1 466 GLLAFVYVYYFVTVGLAMLHFAIFAMLTS-RHPRPWFNAIAVGFRLicAVILISQIAFGKNFDLTYK 531
                 55788999999999999999999999943.3355666666664443114555555555544333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (555 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       544  (0.0303419); expected 358.6 (0.02)
Passed bias filter:                      233  (0.0129957); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.40
# Mc/sec: 4140.20
//
Query:       EEA22155.1  [L=1629]
Description: Pfs, NACHT, and Ankyrin domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.6e-29  100.6   3.0    2.3e-10   40.9   0.0    9.7 11  Ank_2           Ankyrin repeats (3 copies)
      1e-13   51.2   1.4    8.4e-07   29.2   0.2    5.5  4  Ank_5           Ankyrin repeats (many copies)
    6.4e-13   48.9   3.5    0.00035   21.1   0.0    8.4 10  Ank_4           Ankyrin repeats (many copies)
    8.8e-13   47.2   0.2       0.65   10.8   0.0    9.7  8  Ank_3           Ankyrin repeat
    4.5e-09   36.4   5.6       0.26   11.8   0.0    9.1  8  Ank             Ankyrin repeat
    1.2e-07   31.2   0.0    3.9e-07   29.6   0.0    1.8  1  PNP_UDP_1       Phosphorylase superfamily
    1.8e-07   31.7   0.0      6e-07   30.0   0.0    1.9  1  AAA_16          AAA ATPase domain
    2.8e-07   30.6   0.0    5.9e-07   29.5   0.0    1.5  1  NACHT           NACHT domain
    0.00068   19.9   0.0     0.0028   17.9   0.0    2.1  1  AAA_22          AAA domain
  ------ inclusion threshold ------
      0.025   14.5   0.0       0.17   11.8   0.0    2.4  2  Ploopntkinase3  P-loop Nucleotide Kinase3
      0.071   13.5   0.0       0.18   12.2   0.0    1.7  1  RNA_helicase    RNA helicase
      0.072   12.4   3.8        2.8    7.2   0.0    3.3  4  FtsK_SpoIIIE    FtsK/SpoIIIE family
       0.24   11.5   8.7        6.7    6.9   0.1    5.1  5  SseB_C          SseB protein C-terminal domain
       0.35   10.4   6.1        3.5    7.2   0.0    4.2  4  AAA_25          AAA domain
        1.2    9.7   5.1         56    4.4   0.2    5.0  5  PepSY_like      Putative beta-lactamase-inhibitor-like, PepSY
        3.7    7.4  13.1         14    5.5   0.0    6.1  6  DUF3868         Domain of unknown function, B. Theta Gene des


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.0   7.4e-05     0.083      24      76 ..     829     905 ..     807     910 .. 0.68
   2 ?    3.2   0.0      0.12   1.3e+02       4      79 ..     916    1002 ..     914    1006 .. 0.56
   3 !    7.1   0.0    0.0072       8.1      10      75 ..     956    1027 ..     944    1036 .. 0.65
   4 !   10.2   0.0   0.00081       0.9       3      80 ..     979    1064 ..     977    1068 .. 0.73
   5 !    8.4   0.0    0.0029       3.2      28      75 ..    1037    1120 ..    1010    1129 .. 0.42
   6 !    8.4   0.0    0.0028       3.1       8      49 ..    1080    1127 ..    1069    1191 .. 0.60
   7 !    7.3   0.0    0.0061       6.9       4      73 ..    1229    1306 ..    1140    1317 .. 0.58
   8 ?    4.2   0.0     0.058        65       7      74 ..    1265    1339 ..    1255    1349 .. 0.58
   9 !   24.6   0.1   2.5e-08   2.8e-05       2      82 ..    1440    1530 ..    1408    1531 .. 0.82
  10 !   40.9   0.0   2.1e-13   2.3e-10       1      83 []    1471    1564 ..    1471    1564 .. 0.87
  11 !   22.9   0.0   8.4e-08   9.4e-05      21      72 ..    1526    1586 ..    1523    1594 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 7.4e-05
       Ank_2  24 k.ngktaLhyAakngnleivklLleh..............adnd........grtpLhyAarsghleivklLlek...g 76 
                 + +g ++ h+Aa+   + +v++ l++                 d        g+tpL  Aa +g++ i++ Ll+    g
  EEA22155.1 829 NiDGFSVFHAAARWRIIPLVSWALSAnrmdsdladhverkY--DdksfkamtGTTPLEEAAGQGNPAILNALLNGleaG 905
                 2589999*******98899*999984455555544444332..134455555*********************433334 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.12
       Ank_2    4 Aakngnl..elvklLl..egadpnkngktaLhyAakngnl..eivklLleh.ad..ndgrtpLhyAarsgh..leivklLlek.gadi 79  
                  Aa+ng++  e++  Ll   g  +    + ++ +Aa n +   +i+  Ll    d  +  + +  +Aar+g+   +i+ lLl++ g +i
  EEA22155.1  916 AAQNGDFgkEIMAVLLdrLGDQIQ-ITEDVVRAAAGNEQSgkDIMTQLLGRrRDqiYITEDIVKVAARNGQsgKDIITLLLDQrGDQI 1002
                  666654444566666653332222.235677777776544447777777654444444667888888886433588888885446555 PP

  == domain 3  score: 7.1 bits;  conditional E-value: 0.0072
       Ank_2   10 lelvklLlegadpnk..ngktaLhyAakngnl..eivklLleh.ad..ndgrtpLhyAarsghleivklLlek 75  
                   +++ +Ll g + ++    + ++ +Aa+ng+   +i+ lLl++  d  +  + +  +Aa+s++ +++ lLl++
  EEA22155.1  956 KDIMTQLL-GRRRDQiyITEDIVKVAARNGQSgkDIITLLLDQrGDqiQITEDVVKAAAQSSSNDVMMLLLDQ 1027
                  36888888.3333312334788999999997667999999998644444456789999988776777777743 PP

  == domain 4  score: 10.2 bits;  conditional E-value: 0.00081
       Ank_2    3 lAakngnl..elvklLl..egadpnkngktaLhyAakngnleivklLleh.ad..ndgrtpLhyAars..ghleivklLlekgadin 80  
                  +Aa+ng++  +++ lLl   g  +    + ++ +Aa++ +++++ lLl++  d  +  + +   Aar+  +  +i+ lLl+++ +i+
  EEA22155.1  979 VAARNGQSgkDIITLLLdqRGDQIQ-ITEDVVKAAAQSSSNDVMMLLLDQhRDqfQITEDVVKTAARNgwNGKDIMTLLLDREDQIQ 1064
                  5888764434799999985554444.4489*******9999*******966554444667999999996635699999997754444 PP

  == domain 5  score: 8.4 bits;  conditional E-value: 0.0029
       Ank_2   28 taLhyAakngnl..eivklLleh..................adnd..................grtpLhyAarsghleivklLlek 75  
                   ++ +Aa+ng +  +i+ lLl+                      +                   +  ++ A+++g+ +++ lLl++
  EEA22155.1 1037 DVVKTAARNGWNgkDIMTLLLDRedqiqitedvikasvtnyW--NgkdimtllldrrgdeiqiTQDLIMTAVEYGSNDVITLLLDR 1120
                  555555555433235555555522222332223222221120..011222222222222233344456666666666666666644 PP

  == domain 6  score: 8.4 bits;  conditional E-value: 0.0028
       Ank_2    8 gnlelvklLl..egadpnkngktaLhyAakngnleivklLleh......a 49  
                  g  +++ lLl   g ++    +  +++A+++g+++++ lLl+       +
  EEA22155.1 1080 G-KDIMTLLLdrRGDEIQ-ITQDLIMTAVEYGSNDVITLLLDRrrdqiqI 1127
                  3.4678888876555554.3378888888888888888888754222221 PP

  == domain 7  score: 7.3 bits;  conditional E-value: 0.0061
       Ank_2    4 AakngnlelvklLl..egadpn.kngktaLhyAakn...gnleivklLleh.ad..ndgrtpLhyAarsgh..leivklLl 73  
                  Aa +g+++++ lLl   g  +  +  + ++ + a+n   g ++i+ lLl++  d  +  + +  +Aar+ h   ei+ lLl
  EEA22155.1 1229 AAASGSNDVMMLLLdqRGDQFQiT--EDVVKATAENaysG-EDIMTLLLDQrGDqfQITEDVVKAAARNRHygKEIMTLLL 1306
                  333454455555554322222111..33333333331112.2555666655422222234455666665432235666665 PP

  == domain 8  score: 4.2 bits;  conditional E-value: 0.058
       Ank_2    7 ngnlelvklLl..egadpnkngktaLhyAakngnl..eivklLleh....adndgrtpLhyAars...ghleivklLle 74  
                  +g  +++ lLl   g  +    + ++ +Aa+n +   ei+ lLl+     + +  + +  +A+++   g + i+ +Ll+
  EEA22155.1 1265 SG-EDIMTLLLdqRGDQFQ-ITEDVVKAAARNRHYgkEIMTLLLDRrgyqF-QVTEDVVKAAVKNrysG-ESIMTVLLD 1339
                  34.4577888864332222.3378888888887666688888888544331.23345666666663322.466666664 PP

  == domain 9  score: 24.6 bits;  conditional E-value: 2.5e-08
       Ank_2    2 hlAakngnlelvklLl.egadpn.k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlek.gadinlk 82  
                    Aa+ gn  +++lL  +g+ +  +   +  L+ Aak+gn   +k Ll+       ++  g tpL +A+  gh+++v+ Ll+   +d+++k
  EEA22155.1 1440 SSAASCGNETILHLLAqNGKQIPiHlLQLARLYNAAKSGNFAKLKQLLSDgtpadtQNIRGVTPLGIASHRGHYRTVEALLQTnQVDVDAK 1530
                  5688888777777777888777654667999********877789999866785555577*********99**********5437777765 PP

  == domain 10  score: 40.9 bits;  conditional E-value: 2.1e-13
       Ank_2    1 LhlAakngnlelvklLl.egadpn.k..ngktaLhyAakngnleivklLleh....ad...ndgrtpLhyAarsghleivklLlekgadinlkd 83  
                  L+ Aak+gn+  +k+Ll  g+ ++ +   g t+L +A ++g+  +v++Ll+     +d    +g++p+++Aa +g+  iv lLle  a++n+ d
  EEA22155.1 1471 LYNAAKSGNFAKLKQLLsDGTPADtQniRGVTPLGIASHRGHYRTVEALLQTnqvdVDaksTTGESPIFLAAACGYASIVWLLLEAHANPNAAD 1564
                  688*****9********87766666348**********************9557664466788*********************9999999865 PP

  == domain 11  score: 22.9 bits;  conditional E-value: 8.4e-08
       Ank_2   21 dpn.k..ngktaLhyAakngnleivklLle.h.....adndgrtpLhyAarsghleivklL 72  
                  d++ k  +g++++++Aa  g+  iv lLle h     ad +g tp  +A r+ h++i+k+L
  EEA22155.1 1526 DVDaKstTGESPIFLAAACGYASIVWLLLEaHanpnaADINGDTPYDMAWRYRHFDIAKIL 1586
                  55552469*********************954677777789******************99 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0     0.067        75      16      39 ..     879     901 ..     877     908 .. 0.84
   2 ?    5.3   0.0     0.024        26      18      41 ..    1100    1123 ..    1087    1130 .. 0.80
   3 !   17.2   0.0   4.3e-06    0.0049       1      52 [.    1486    1537 ..    1486    1538 .. 0.89
   4 !   29.2   0.2   7.5e-10   8.4e-07       1      56 []    1519    1574 ..    1519    1574 .. 0.96

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.067
       Ank_5  16 gntpLhvAakygaadvvrlLlarg 39 
                 g+tpL  Aa +g++ +++ Ll +g
  EEA22155.1 879 GTTPLEEAAGQGNPAILNALL-NG 901
                 89*******************.33 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.024
       Ank_5   18 tpLhvAakygaadvvrlLlargad 41  
                    +++A++yg+ dv+ lLl+r+ d
  EEA22155.1 1100 DLIMTAVEYGSNDVITLLLDRRRD 1123
                  689****************88766 PP

  == domain 3  score: 17.2 bits;  conditional E-value: 4.3e-06
       Ank_5    1 Llehg.padvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGlta 52  
                  Ll+ g pad+++   +g+tpL +A+++g+ + v+ Ll  +++d +++   G+++
  EEA22155.1 1486 LLSDGtPADTQNI--RGVTPLGIASHRGHYRTVEALLqTNQVDVDAKSTTGESP 1537
                  6778877777665..599*********************************998 PP

  == domain 4  score: 29.2 bits;  conditional E-value: 7.5e-10
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56  
                  Ll+  ++dv+++   g++p+ +Aa +g+a++v lLl+ +a++n+ d +G+t++d+A
  EEA22155.1 1519 LLQTNQVDVDAKSTTGESPIFLAAACGYASIVWLLLEAHANPNAADINGDTPYDMA 1574
                  677778************************************************99 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.0         1   1.2e+03       5      23 ..     457     475 ..     455     524 .. 0.84
   2 ?    1.9   0.0      0.31   3.5e+02      31      54 ..     828     851 ..     810     852 .. 0.74
   3 ?   -1.0   0.0       2.7     3e+03      36      55 .]     880     899 ..     854     907 .. 0.72
   4 ?   -2.4   0.0       7.2     8e+03       6      22 ..    1010    1026 ..    1007    1032 .. 0.82
   5 ?   -1.2   0.0         3   3.4e+03       6      24 ..    1165    1183 ..    1162    1208 .. 0.82
   6 ?   -0.5   0.0       1.8   2.1e+03       6      23 ..    1227    1244 ..    1224    1250 .. 0.85
   7 ?    0.9   0.0      0.68   7.7e+02       2      27 ..    1436    1461 ..    1435    1465 .. 0.85
   8 !   21.1   0.0   3.1e-07   0.00035       5      55 .]    1471    1520 ..    1467    1520 .. 0.95
   9 !   10.1   0.0   0.00088      0.99      11      54 ..    1510    1553 ..    1509    1554 .. 0.89
  10 !   13.1   0.1    0.0001      0.11       8      54 ..    1541    1586 ..    1534    1586 .. 0.79

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 1
       Ank_4   5 LhyaaisgrlelvrlLlek 23 
                 L y+ i++r +l+++Ll+k
  EEA22155.1 457 LLYQLIHQRPRLIKYLLAK 475
                 5689999*********975 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.31
       Ank_4  31 dnrsGetalhiAakrgnveilklL 54 
                  n++G++ +h Aa++  +  + + 
  EEA22155.1 828 GNIDGFSVFHAAARWRIIPLVSWA 851
                 5899*********99888888776 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 2.7
       Ank_4  36 etalhiAakrgnveilklLl 55 
                  t+l  Aa  gn+ il  Ll
  EEA22155.1 880 TTPLEEAAGQGNPAILNALL 899
                 45555555555555554443 PP

  == domain 4  score: -2.4 bits;  conditional E-value: 7.2
       Ank_4    6 hyaaisgrlelvrlLle 22  
                   +aa+s+  ++ +lLl+
  EEA22155.1 1010 KAAAQSSSNDVMMLLLD 1026
                  57888**********96 PP

  == domain 5  score: -1.2 bits;  conditional E-value: 3
       Ank_4    6 hyaaisgrlelvrlLlekg 24  
                   +aa+sg  ++ ++Ll+++
  EEA22155.1 1165 EAAAASGSNDVMMILLDQR 1183
                  67999***********864 PP

  == domain 6  score: -0.5 bits;  conditional E-value: 1.8
       Ank_4    6 hyaaisgrlelvrlLlek 23  
                   +aa+sg  ++ +lLl++
  EEA22155.1 1227 EAAAASGSNDVMMLLLDQ 1244
                  68999***********86 PP

  == domain 7  score: 0.9 bits;  conditional E-value: 0.68
       Ank_4    2 ltaLhyaaisgrlelvrlLlekgadi 27  
                  +++L +aa+ g++ +++lL ++g++i
  EEA22155.1 1436 TDVLSSAASCGNETILHLLAQNGKQI 1461
                  67889999999999999999999986 PP

  == domain 8  score: 21.1 bits;  conditional E-value: 3.1e-07
       Ank_4    5 LhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  L +aa+sg++  ++ Ll+ g   + q n++G t+l iA  rg+++ ++ Ll
  EEA22155.1 1471 LYNAAKSGNFAKLKQLLSDGTPADTQ-NIRGVTPLGIASHRGHYRTVEALL 1520
                  6789**********************.*********************997 PP

  == domain 9  score: 10.1 bits;  conditional E-value: 0.00088
       Ank_4   11 sgrlelvrlLlek.gadinaqdnrsGetalhiAakrgnveilklL 54  
                   g++++v+ Ll++  +d++a  +  Ge+++  Aa  g+ +i+ lL
  EEA22155.1 1510 RGHYRTVEALLQTnQVDVDAK-STTGESPIFLAAACGYASIVWLL 1553
                  69**********968*****9.999************99988666 PP

  == domain 10  score: 13.1 bits;  conditional E-value: 0.0001
       Ank_4    8 aaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54  
                  aa+ g   +v lLle  a++na  +++G+t+ ++A++  +++i+k L
  EEA22155.1 1541 AAACGYASIVWLLLEAHANPNAA-DINGDTPYDMAWRYRHFDIAKIL 1586
                  44444444455777********8.*******************9976 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0         2   2.3e+03       1      25 [.     831     855 ..     831     860 .. 0.82
   2 !    7.0   0.0    0.0097        11       4      23 ..     881     900 ..     878     908 .. 0.87
   3 ?   -1.7   0.0       6.7   7.5e+03       9      26 ..     980     999 ..     979    1002 .. 0.81
   4 ?    3.3   0.0      0.15   1.7e+02       5      23 ..    1101    1119 ..    1098    1124 .. 0.86
   5 ?    2.5   0.0      0.29   3.2e+02       6      26 ..    1439    1458 ..    1438    1464 .. 0.71
   6 ?    1.7   0.0      0.51   5.7e+02       6      28 ..    1471    1492 ..    1470    1495 .. 0.84
   7 !   10.8   0.0   0.00058      0.65       2      31 .]    1500    1529 ..    1499    1529 .. 0.93
   8 ?    6.4   0.1     0.015        16       2      31 .]    1534    1562 ..    1533    1562 .. 0.82

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 2
       Ank_3   1 nGetpLhlAarsgnleivkfLlenk 25 
                 +G + +h Aar   +++v + l  +
  EEA22155.1 831 DGFSVFHAAARWRIIPLVSWALSAN 855
                 58899******99999999988755 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0097
       Ank_3   4 tpLhlAarsgnleivkfLle 23 
                 tpL +Aa +gn++i+ +Ll+
  EEA22155.1 881 TPLEEAAGQGNPAILNALLN 900
                 9******************9 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 6.7
       Ank_3   9 Aarsgnl..eivkfLlenkg 26 
                 Aar+g    +i+ +Ll+++g
  EEA22155.1 980 AARNGQSgkDIITLLLDQRG 999
                 99999998779999999554 PP

  == domain 4  score: 3.3 bits;  conditional E-value: 0.15
       Ank_3    5 pLhlAarsgnleivkfLle 23  
                  ++++A+++g+ +++ +Ll+
  EEA22155.1 1101 LIMTAVEYGSNDVITLLLD 1119
                  789*********9999998 PP

  == domain 5  score: 2.5 bits;  conditional E-value: 0.29
       Ank_3    6 LhlAarsgnleivkfLlenkg 26  
                  L  Aa++gn +i+++L + +g
  EEA22155.1 1439 LSSAASCGNETILHLLAQ-NG 1458
                  566888888887777777.44 PP

  == domain 6  score: 1.7 bits;  conditional E-value: 0.51
       Ank_3    6 LhlAarsgnleivkfLlenkgad 28  
                  L+ Aa+sgn++ +k Ll   g +
  EEA22155.1 1471 LYNAAKSGNFAKLKQLLS-DGTP 1492
                  788*******98***999.6765 PP

  == domain 7  score: 10.8 bits;  conditional E-value: 0.00058
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvna 31  
                  G tpL +A + g++  v++Ll+ + +dv+a
  EEA22155.1 1500 GVTPLGIASHRGHYRTVEALLQTNQVDVDA 1529
                  78************99******99***985 PP

  == domain 8  score: 6.4 bits;  conditional E-value: 0.015
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvna 31  
                  Ge+p++lAa +g  + + +Ll + +a++na
  EEA22155.1 1534 GESPIFLAAACGYAS-IVWLLLEAHANPNA 1562
                  9**************.55555558999995 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0         2   2.3e+03       1      17 [.     831     844 ..     831     855 .. 0.84
   2 ?    0.9   0.0      0.64   7.2e+02       2      24 ..     879     901 ..     878     908 .. 0.82
   3 ?    2.8   0.0      0.16   1.8e+02       9      24 ..     980     999 ..     977    1006 .. 0.80
   4 ?    0.5   0.0      0.89   9.9e+02       7      23 ..    1103    1119 ..    1101    1129 .. 0.78
   5 ?   -1.1   0.0       2.9   3.2e+03      13      24 ..    1141    1154 ..    1134    1160 .. 0.72
   6 ?   -0.8   0.0       2.2   2.5e+03       4      14 ..    1449    1459 ..    1442    1497 .. 0.69
   7 !   11.8   0.0   0.00023      0.26       2      30 ..    1500    1530 ..    1499    1532 .. 0.86
   8 !   10.0   0.1   0.00084      0.95       2      31 ..    1534    1564 ..    1533    1565 .. 0.90

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 2
                 TSBBHHHHHHHHTTHHH CS
         Ank   1 dGnTPLHlAatngkkri 17 
                 dG+++ H Aa+     i
  EEA22155.1 831 DGFSVFHAAARWR---I 844
                 8********9764...4 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.64
                 SBBHHHHHHHHTTHHHHHHHHTT CS
         Ank   2 GnTPLHlAatngkkriiklLLhG 24 
                 G TPL  Aa  g++ i+ +LL+G
  EEA22155.1 879 GTTPLEEAAGQGNPAILNALLNG 901
                 889******889999*****966 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.16
                 HHHHTT..HHHHHHHH.T.T CS
         Ank   9 Aatngk..kriiklLL.h.G 24 
                 Aa+ng+  k+ii lLL + G
  EEA22155.1 980 AARNGQsgKDIITLLLdQrG 999
                 88888899********7535 PP

  == domain 4  score: 0.5 bits;  conditional E-value: 0.89
                  HHHHHHTTHHHHHHHHT CS
         Ank    7 HlAatngkkriiklLLh 23  
                  + A+ +g+ ++i lLL+
  EEA22155.1 1103 MTAVEYGSNDVITLLLD 1119
                  6688888899*****94 PP

  == domain 5  score: -1.1 bits;  conditional E-value: 2.9
                  TTHHHHHHHH..TT CS
         Ank   13 gkkriiklLL..hG 24  
                  +kk ii lLL  +G
  EEA22155.1 1141 NKKGIITLLLdqQG 1154
                  5566******8447 PP

  == domain 6  score: -0.8 bits;  conditional E-value: 2.2
                  BHHHHHHHHTT CS
         Ank    4 TPLHlAatngk 14  
                  T LHl a+ngk
  EEA22155.1 1449 TILHLLAQNGK 1459
                  78997676666 PP

  == domain 7  score: 11.8 bits;  conditional E-value: 0.00023
                  SBBHHHHHHHHTTHHHHHHHH.TT.TSTTCB CS
         Ank    2 GnTPLHlAatngkkriiklLL.hG.Anlnal 30  
                  G TPL +A+++g+ r +++LL     +++a+
  EEA22155.1 1500 GVTPLGIASHRGHYRTVEALLqTNqVDVDAK 1530
                  99*******************6344888886 PP

  == domain 8  score: 10.0 bits;  conditional E-value: 0.00084
                  SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAnlnald 31  
                  G +P  lAa +g ++i+ lLL   An+na d
  EEA22155.1 1534 GESPIFLAAACGYASIVWLLLeAHANPNAAD 1564
                  88999999999**********7679****98 PP

>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.6   0.0   3.5e-10   3.9e-07       3     201 ..      14     280 ..      12     298 .. 0.75

  Alignments for each domain:
  == domain 1  score: 29.6 bits;  conditional E-value: 3.5e-10
                 EEEESSHHHHHHHHHHEEEEEEEEEE....TTEEEEEEEETTEEEEEEE--...SSHHHHHHHHHHHHHHHC--SEE.EEEEEEEES..STTT-TT-EE CS
   PNP_UDP_1   3 aiivgspgevellaespleetpfgre...grgfkfvtGtlkgkpvvivstG...iGkpnaavvaeirllkefgvkai.iriGtaGgl..npdlkvGDvv 92 
                 a i++ p e+++ +   lee++ + +        +++G+++g++vvi++      G+++a  +  + +l  f + ++ + +G+ Gg+  ++d+++GDvv
  EEA22155.1  14 AWICALPLEMAAAKVM-LEEIHGRLPqprTDHNAYTLGKIHGHNVVIACLPsgiYGTTSAT-IVLTQMLPTFPSLRFgLLVGIGGGVpgKADVRLGDVV 110
                 6678888666666666.55555555555568999*************99777755999999.7777777778666665899*******9********** PP

                 EEEEEEESSSCCG.CCTHHCC..................................................................TCCCCTTSSEE- CS
   PNP_UDP_1  93 ipddainfdgrsp.lygpkee..................................................................gqyfpdsydapa 124
                 i++     +g  + +yg+                                                                       ++  ++d   
  EEA22155.1 111 ISKPTASGSGVVQyDYGKT-VqdrcfqrtgflnkppqilltaisqmesdrimgarqikqsivgvlegnrdmahkfsepdndwlfpatYLHQGNPQDC-S 207
                 ****665444444133333.24777888899999999********9999999999998888888888888888888888888885442222222222.2 PP

                 -HHHHHHHHHCHHTTT.TTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHTT--EEEEEEEEETT CS
   PNP_UDP_1 125 dpelrallkeaaealg.ikvhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArelgipfaairvvsdla 201
                   +l +l +++++ +  + +h G++a++++   + + ++++ ++l + + eME+a +  l     +p+++ir++ d+ 
  EEA22155.1 208 ACDLNQLSHRQPRTMSgPYLHLGLIASGNQLLKDAQTRDQIAKELDVLCFEMEAAGLMDL-----LPCLVIRGICDYC 280
                 24555555555555557*************************************998877.....6777777777744 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.0   0.0   5.4e-10     6e-07       9     159 ..     380     528 ..     378     538 .. 0.79

  Alignments for each domain:
  == domain 1  score: 30.0 bits;  conditional E-value: 5.4e-10
      AAA_16   9 leqLlsale.rvrsgrp...elvllsGesGvGKsslvrellralekd......ggiflrgkcdqlesaipysa.laqalareellrqlldeaesaelea 96 
                 +e+L++ le + + ++    +++ l+G +G+GKs++v +  ++l k+      + ++++  cd++e++ + ++ +++ l   +l+ q  +  +  +l+ 
  EEA22155.1 380 TEELTDWLEgS-KNDDRngsNILWLHGTPGSGKSTMVITMTDELPKQpafnsgNKVLAYFFCDSSEENQRTAIsILRGL-LYQLIHQRPRLIKY-LLAK 475
                 56677777742.22222355*****************999999999988888435559999999988887777788888.44999999988666.8888 PP

      AAA_16  97 wrekleealaavpelagaeasrllellkrll.allsrderplvlvlDdlqwadeaslql.laaLl 159
                 + ++ ++ ++           ++ +l++ ll + +++ +  ++  +D l+  +++s+q  l+++ 
  EEA22155.1 476 YLDRKDTLFT-----------SFDALWTVLLeMGAES-SCEIYCMIDALDECEPDSQQTlLRQIN 528
                 9998888888...........9999999999888888.555*****************9676655 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.5   0.0   5.3e-10   5.9e-07       2     110 ..     400     528 ..     399     576 .. 0.70

  Alignments for each domain:
  == domain 1  score: 29.5 bits;  conditional E-value: 5.3e-10
                 CEEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-........-HCHHHCCCCTS--SSS-C...............CHHHHCCSC CS
       NACHT   2 lvilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgna.....rsladllfsqlpepaapvse...............vwavllelp 80 
                 +++l+G +GsGK+t++  + +++ ++  ++   k++ ++++ + ++ +++     r+l ++l  q p +++                            
  EEA22155.1 400 ILWLHGTPGSGKSTMVITMTDELPKQPAFNSGNKVLAYFFCDSSEENQRTaisilRGLLYQLIHQRPRLIKYLLAkyldrkdtlftsfdaL-------- 490
                 58*********************88877776667777777777777666666888667777777766666666556666555544455554........ PP

                 CCEE...............EEEE-STT-SS-TCH.........HH CS
       NACHT  81 erlL...............lilDglDelvtdlgqkekqpvrtlLs 110
                    +                 +D+lDe++ d +q     + + ++
  EEA22155.1 491 ---WtvllemgaessceiyCMIDALDECEPDSQQ----TLLRQIN 528
                 ...2444455555557777***********8888....3333333 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.0   2.5e-06    0.0028       4      71 ..     397     488 ..     394     548 .. 0.61

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 2.5e-06
      AAA_22   4 tagilvvtGesGtGKTtllrrlleqldeeakaee.erpevvfvtlpsst...sskdllrellralglelka....................e 71 
                 + +il ++G +G+GK+t + +++++l+++++ +  +++  +f++ +s++   +  ++lr ll +l +++ +                     
  EEA22155.1 397 GSNILWLHGTPGSGKSTMVITMTDELPKQPAFNSgNKVLAYFFCDSSEEnqrTAISILRGLLYQLIHQRPRlikyllakyldrkdtlftsfD 488
                 568999********************998888885444444444444444555556666666666555544555555554444444444440 PP

>> Ploopntkinase3  P-loop Nucleotide Kinase3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   0.00015      0.17       5      46 ..     400     441 ..     397     450 .. 0.83
   2 ?   -2.3   0.0       3.2   3.6e+03      46      76 ..    1107    1137 ..    1088    1185 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00015
  Ploopntkinase3   5 liylvGqPGaGkstlmaeltkgfdrskveqeeetvphdvlvd 46 
                     +++l G+PG+Gkst++ ++t+ + +++  ++ ++v ++ + d
      EEA22155.1 400 ILWLHGTPGSGKSTMVITMTDELPKQPAFNSGNKVLAYFFCD 441
                     7899******************99998876667787777666 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 3.2
  Ploopntkinase3   46 drttGevvgaelGkrreafsGtdalassiid 76  
                      ++ + +v++  l +rr++   t+ l  +i+ 
      EEA22155.1 1107 EYGSNDVITLLLDRRRDQIQITEDLVKAIVG 1137
                      5556678888888899998888888888874 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00016      0.18       1      32 [.     401     432 ..     401     444 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00016
  RNA_helicase   1 iwlyGpsgeGKStlakeLakallkklklkkkd 32 
                   +wl+G +g GKSt++ +++++l k+  +++ +
    EEA22155.1 401 LWLHGTPGSGKSTMVITMTDELPKQPAFNSGN 432
                   6****************999998776555544 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   0.0    0.0025       2.8      41      59 ..     399     418 ..     360     420 .. 0.82
   2 ?   -2.4   0.0       2.1   2.4e+03      63      95 ..    1011    1043 ..    1008    1075 .. 0.82
   3 ?   -3.8   0.0       5.8   6.5e+03      63      90 ..    1166    1193 ..    1163    1198 .. 0.81
   4 ?    4.0   0.8     0.024        27      63     172 ..    1228    1341 ..    1223    1373 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0025
                   SEE.EE--TTSSHHHHHHHH CS
  FtsK_SpoIIIE  41 hll.vaGatgsGKStalntL 59 
                   ++l ++G++gsGKSt++ t+
    EEA22155.1 399 NILwLHGTPGSGKSTMVITM 418
                   554389**********9988 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 2.1
                    HHTT--TTTEEEEEE-TTSSSCGGGTT-TTBSS CS
  FtsK_SpoIIIE   63 latthtPeeVqliliDykgvelsalediphlls 95  
                    +a+ ++ ++V ++l+D    +++  ed+ ++++
    EEA22155.1 1011 AAAQSSSNDVMMLLLDQHRDQFQITEDVVKTAA 1043
                    788899999999999999889998888876665 PP

  == domain 3  score: -3.8 bits;  conditional E-value: 5.8
                    HHTT--TTTEEEEEE-TTSSSCGGGTT- CS
  FtsK_SpoIIIE   63 latthtPeeVqliliDykgvelsaledi 90  
                    +a+ +  ++V +il+D  g +++  ed+
    EEA22155.1 1166 AAAASGSNDVMMILLDQRGDQFQITEDV 1193
                    677788899*******998899988886 PP

  == domain 4  score: 4.0 bits;  conditional E-value: 0.024
                    HHTT--TTTEEEEEE-TTSSSCGGGTT-TTBSS.S-B-SHHHHHHHHHHHHHHHHHHHHHHHHTT-SSHHH...HHHHHHHHHHTT---B-TT-. CS
  FtsK_SpoIIIE   63 latthtPeeVqliliDykgvelsalediphllsvavatdperalraleeLvkemeeryalfreagvrsiaa...ydgeiaedpldifgdvflvlD 154 
                    +a+ +  ++V ++l+D  g +++  ed+   ++ a a++++    ++  L++++ + +++ ++  v+  a+   y +ei +  ld++g +f v  
    EEA22155.1 1228 AAAASGSNDVMMLLLDQRGDQFQITEDV---VK-ATAENAYSGEDIMTLLLDQRGDQFQITED-VVKAAARnrhYGKEIMTLLLDRRGYQFQVTE 1317
                    677788899*********8899998875...66.7789*****************99987655.44444444799******************** PP

                    ........................ CS
  FtsK_SpoIIIE  155 nyddlaaene......ritsLsnq 172 
                    +  + a++n         ++L  +
    EEA22155.1 1318 DVVKAAVKNRysgesiMTVLLDRR 1341
                    ******999988886333334444 PP

>> SseB_C  SseB protein C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.1      0.54   6.1e+02      49      95 ..     990    1037 ..     977    1075 .. 0.63
   2 ?    2.1   0.1      0.18     2e+02      46      92 ..    1142    1189 ..    1131    1197 .. 0.77
   3 ?    6.9   0.1     0.006       6.7      45      98 ..    1171    1227 ..    1162    1231 .. 0.84
   4 ?    2.0   0.1       0.2   2.2e+02      46      95 ..    1234    1286 ..    1226    1292 .. 0.82
   5 ?    2.4   0.1      0.15   1.6e+02      45      98 ..    1359    1412 ..    1348    1416 .. 0.83

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.54
      SseB_C   49 slligvdlegdteklfkdagevaaeylpegepvdlvllde..eq.pvaky 95  
                   + + +d  gd  ++ +d+ ++aa+     + v ++lld+  +q ++ ++
  EEA22155.1  990 IITLLLDQRGDQIQITEDVVKAAAQSSS--NDVMMLLLDQhrDQfQITED 1037
                  5566666666766777777776666664..56666666664333444433 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.18
      SseB_C   46 ekpslligvdlegdteklfkdagevaaeylpegepvdlvllde..eq.pv 92  
                  +k  + + +d +gd  ++ +d+ e+aa+     + v ++lld+  +q ++
  EEA22155.1 1142 KKGIITLLLDQQGDQVQITQDVVEAAAASGS--NDVMMILLDQrgDQfQI 1189
                  566678899***************9998884..89999999995555555 PP

  == domain 3  score: 6.9 bits;  conditional E-value: 0.006
      SseB_C   45 nekpslligvdlegdteklfkdagevaaeylpegepvdlvllde..eq.pvakylle 98  
                  + + +++i +d  gd  ++ +d+ ++aa+   +g+ + ++lld+  +q ++ ++++e
  EEA22155.1 1171 GSNDVMMILLDQRGDQFQITEDVVKAAAGNYRNGKGIMILLLDQkgDQvQITQDVVE 1227
                  367899**************************************6666666666665 PP

  == domain 4  score: 2.0 bits;  conditional E-value: 0.2
      SseB_C   46 ekpslligvdlegdteklfkdagevaaeylpegepvdlvllde..eq.pvaky 95  
                   + ++++ +d  gd  ++ +d+ ++ ae +  ge + ++lld+  +q ++ ++
  EEA22155.1 1234 SNDVMMLLLDQRGDQFQITEDVVKATAENAYSGEDIMTLLLDQrgDQfQITED 1286
                  678999************************************96555565555 PP

  == domain 5  score: 2.4 bits;  conditional E-value: 0.15
      SseB_C   45 n..ekpslligvdlegdteklfkdagevaaeylpegepvdlvlldeeqpvakylle 98  
                  +  +k+ + + +d  gd  ++ +d+ ++aae +  g+++ ++++ e  +v k +  
  EEA22155.1 1359 EysGKKIMTVLFDRRGDQIRITEDVTKAAAENMLSGKEIMTIQITE--DVVKAAAG 1412
                  2456778889999999****************************99..88887665 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   0.0    0.0031       3.5      37      98 ..     402     463 ..     392     499 .. 0.74
   2 ?   -0.2   0.1      0.55   6.2e+02     112     150 ..     989    1027 ..     950    1037 .. 0.81
   3 ?    1.3   0.5      0.19   2.2e+02     110     151 ..    1141    1183 ..    1038    1199 .. 0.80
   4 ?   -0.1   0.1      0.53     6e+02     114     151 ..    1208    1245 ..    1191    1264 .. 0.78

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0031
      AAA_25  37 llaGapgtGKttlaldlalavatGkpwlgpvapeqgkVlyvsaEdsedelrrRlravgeal.....r 98 
                  l G pg+GK+t+++ +  ++ + +p +        kVl + ++ds +e +r +  +++ l      
  EEA22155.1 402 WLHGTPGSGKSTMVITMTDELPK-QPAFN----SGNKVLAYFFCDSSEENQRTAISILRGLlyqliH 463
                 589************99988874.77777....6789999999999999998888888776554440 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.55
      AAA_25  112 eslpLfakdrggtl.ltadvdaleaaieevegvrlvviDp 150 
                  + ++L+ ++rg+++ +t+dv + +a+  + ++v ++ +D 
  EEA22155.1  989 DIITLLLDQRGDQIqITEDVVKAAAQSSS-NDVMMLLLDQ 1027
                  4578999999***9******998888888.8999999996 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.19
      AAA_25  110 gv.eslpLfakdrggtl.ltadvdaleaaieevegvrlvviDpl 151 
                  ++ + ++L+ +++g+++ +t+dv + +aa  + ++v ++ +D  
  EEA22155.1 1141 NKkGIITLLLDQQGDQVqITQDVVEAAAASGS-NDVMMILLDQR 1183
                  44466888889999999999999999988888.89999999976 PP

  == domain 4  score: -0.1 bits;  conditional E-value: 0.53
      AAA_25  114 lpLfakdrggtl.ltadvdaleaaieevegvrlvviDpl 151 
                  + L+ +++g+++ +t+dv + +aa  + ++v ++ +D  
  EEA22155.1 1208 MILLLDQKGDQVqITQDVVEAAAASGS-NDVMMLLLDQR 1245
                  556777888888999999998888888.89999999976 PP

>> PepSY_like  Putative beta-lactamase-inhibitor-like, PepSY-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       4.6   5.1e+03      15      53 ..     836     874 ..     835     879 .. 0.87
   2 ?    0.3   0.0      0.96   1.1e+03      36      78 ..    1065    1108 ..    1057    1110 .. 0.76
   3 ?   -0.2   0.0       1.3   1.5e+03      35      67 ..    1250    1283 ..    1245    1289 .. 0.77
   4 ?    2.9   0.3      0.15   1.7e+02      34      70 ..    1314    1353 ..    1299    1365 .. 0.78
   5 ?    4.4   0.2      0.05        56      36      70 ..    1348    1382 ..    1344    1391 .. 0.85

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 4.6
                 E-TTS-EEEEE-TTSEESGGGS-HHHHHHHHHHTTTEEE CS
  PepSY_like  15 FdkkGeWkeiegkkteiplsilpkavlkaiknsypdekv 53 
                 F + + W+ i   +++++ + +++  +++++ +y d+++
  EEA22155.1 836 FHAAARWRIIPLVSWALSANRMDSDLADHVERKYDDKSF 874
                 788899999999999******************998654 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.96
                  S-HHHHHHHHHHTTT.EEEEEEEECSSEEEEEETTSEEEEEETT CS
  PepSY_like   36 lpkavlkaiknsypd.ekvtkierkkkeyeieleneielyfded 78  
                  + + v+ka  ++y + +++  +  ++++ ei++++++ ++  e+
  EEA22155.1 1065 ITEDVIKASVTNYWNgKDIMTLLLDRRGDEIQITQDLIMTAVEY 1108
                  66677777777755559*****99*********99877765555 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 1.3
                  GS-HHHHHHHHHH.TTTEEEEEEEECSSEEEEEE CS
  PepSY_like   35 ilpkavlkaikns.ypdekvtkierkkkeyeiel 67  
                  ++ + v+ka +++ y++e++  +  ++++  +++
  EEA22155.1 1250 QITEDVVKATAENaYSGEDIMTLLLDQRGDQFQI 1283
                  57788889998888*****998877776665555 PP

  == domain 4  score: 2.9 bits;  conditional E-value: 0.15
                  GGS-HHHHHHHHHHTTTEEEEEEEECSSEEEEEETT...S CS
  PepSY_like   34 silpkavlkaiknsypdekvtkierkkkeyeielen...e 70  
                  ++ ++ v+ a+kn y++e++  +  ++++  i++++   +
  EEA22155.1 1314 QVTEDVVKAAVKNRYSGESIMTVLLDRRGDQIQITEdvvK 1353
                  55567788899999***99999999999999998874443 PP

  == domain 5  score: 4.4 bits;  conditional E-value: 0.05
                  S-HHHHHHHHHHTTTEEEEEEEECSSEEEEEETTS CS
  PepSY_like   36 lpkavlkaiknsypdekvtkierkkkeyeielene 70  
                   ++ v+ a+kn+y+++k+  + +++++  i ++++
  EEA22155.1 1348 TEDVVKAAVKNEYSGKKIMTVLFDRRGDQIRITED 1382
                  466789999999*************9999998875 PP

>> DUF3868  Domain of unknown function, B. Theta Gene description (DUF3868)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.1       0.6   6.7e+02      20      60 ..     979    1018 ..     971    1024 .. 0.70
   2 ?    5.5   0.0     0.013        14      30      65 ..    1081    1116 ..    1065    1118 .. 0.82
   3 ?   -1.2   0.1       1.6   1.8e+03      35      50 ..    1148    1163 ..    1136    1178 .. 0.79
   4 ?   -0.2   0.0      0.77   8.7e+02      26      50 ..    1201    1225 ..    1191    1240 .. 0.76
   5 ?    2.5   0.0      0.11   1.3e+02      17      50 ..    1255    1287 ..    1243    1291 .. 0.87
   6 ?    0.8   0.1      0.38   4.3e+02      19      56 ..    1321    1357 ..    1315    1365 .. 0.78

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.6
     DUF3868   20 aeaqrsyegkisvkpvqleqkGdslhidididlenvkvksa 60  
                    a++ ++gk  +  + l+q+Gd+++i+ d+   + + +s+
  EEA22155.1  979 VAARNGQSGKD-IITLLLDQRGDQIQITEDVVKAAAQSSSN 1018
                  55666666663.44488**********99987666666665 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.013
     DUF3868   30 isvkpvqleqkGdslhidididlenvkvksahsvel 65  
                   ++  + l+++Gd+++i+ d+ + +v+  s+  + l
  EEA22155.1 1081 KDIMTLLLDRRGDEIQITQDLIMTAVEYGSNDVITL 1116
                  4677789********************999998876 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 1.6
     DUF3868   35 vqleqkGdslhididi 50  
                  + l+q+Gd+++i+ d+
  EEA22155.1 1148 LLLDQQGDQVQITQDV 1163
                  559*********9886 PP

  == domain 4  score: -0.2 bits;  conditional E-value: 0.77
     DUF3868   26 yegkisvkpvqleqkGdslhididi 50  
                  y +  ++  + l+qkGd+++i+ d+
  EEA22155.1 1201 YRNGKGIMILLLDQKGDQVQITQDV 1225
                  555556666789*********9886 PP

  == domain 5  score: 2.5 bits;  conditional E-value: 0.11
     DUF3868   17 igeaeaqrsyegkisvkpvqleqkGdslhididi 50  
                  + +a+a+++y+g+ ++  + l+q+Gd+ +i+ d+
  EEA22155.1 1255 VVKATAENAYSGE-DIMTLLLDQRGDQFQITEDV 1287
                  67899*******9.67779********9998765 PP

  == domain 6  score: 0.8 bits;  conditional E-value: 0.38
     DUF3868   19 eaeaqrsyegkisvkpvqleqkGdslhidididlenvk 56  
                  +a  ++ y+g+ s+  v l+++Gd+++i+ d+   +vk
  EEA22155.1 1321 KAAVKNRYSGE-SIMTVLLDRRGDQIQITEDVVKAAVK 1357
                  55566788887.566699**********9888766665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1629 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       714  (0.0398237); expected 358.6 (0.02)
Passed bias filter:                      551  (0.0307323); expected 358.6 (0.02)
Passed Vit filter:                        67  (0.00373696); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              16  [number of targets reported over threshold]
# CPU time: 1.04u 0.32s 00:00:01.36 Elapsed: 00:00:00.48
# Mc/sec: 10134.40
//
Query:       EEA22156.1  [L=397]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       245  (0.013665); expected 358.6 (0.02)
Passed bias filter:                      221  (0.0123264); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2981.09
//
Query:       EEA22157.1  [L=787]
Description: alpha-N-acetylglucosaminidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.7e-130  434.9   7.5   1.7e-130  434.9   7.5    1.5  2  NAGLU     Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel do
    2.2e-66  224.1   1.6    3.7e-66  223.4   1.6    1.3  1  NAGLU_C   Alpha-N-acetylglucosaminidase (NAGLU) C-terminal do
    2.9e-19   68.6   0.0    7.2e-19   67.4   0.0    1.7  1  NAGLU_N   Alpha-N-acetylglucosaminidase (NAGLU) N-terminal do


Domain annotation for each model (and alignments):
>> NAGLU  Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  434.9   7.5  2.8e-134  1.7e-130       1     332 [.     129     464 ..     129     465 .. 0.98
   2 ?   -3.3   0.0      0.55   3.3e+03     247     290 ..     613     656 ..     607     664 .. 0.80

  Alignments for each domain:
  == domain 1  score: 434.9 bits;  conditional E-value: 2.8e-134
                 EEE--TTHHHHTTTT--HHHHHHHHHHHHHTT--EEE--TTHHHHHHHHHGGGT--HHHHHHHS--TT-HHHHHTTS--S.TT----TTHHHHHHHHHH CS
       NAGLU   1 RyylNvctfsYtmafwdwerWereiDwmAlnGinlpLaivGqeavwqevlkelglsdeeikeflsgpaflawqrmgnleg.wggplpqswiekqaeLqk 98 
                 Ry++N++tf+Y +afw+w++We ++DwmAl+Ginl La+vG+e+++ ev+kelgl+d+ei++f++gpaf+aw+r+gn++g wg plp++wie+q+eLqk
  EEA22157.1 129 RYHFNTVTFDYMAAFWSWSDWEFQLDWMALRGINLSLAWVGYEKILLEVFKELGLTDAEISTFFTGPAFQAWNRLGNIQGfWGDPLPNEWIESQFELQK 227
                 9*******************************************************************************99***************** PP

                 HHHHHHHHHT-EEEEE--S-EE-TTHHHHSTT--EE---EETT....EE--EEE-SS--HHHHHHHHHHHHHHHHH-.--SEEE--TTTTS-..--TT- CS
       NAGLU  99 kilkrmrelgmtpvlpaFaGhvPkalkeklpkakvteqgewsg....fkrpafldptdplfakiakafleeqkklyg.tshiYaaDpFnEgepkssdee 192
                 kil+rm elg+tpvlp+F+G+vP+a++++lp+akv++ ++w+     +++++fl+p d++fa ++k+ +++q++ yg  shiYa+D++nE++p ss+++
  EEA22157.1 228 KILARMVELGITPVLPSFTGFVPRAITRVLPNAKVVPGSRWNVfssnYTCDTFLEPFDDNFALLQKSTISKQQAYYGnISHIYALDQYNENNPFSSNPD 326
                 *****************************************9888899*****************************99******************** PP

                 -HHHHHHHHHHHHHHH-TT-EEEEEEBTT.........BS-HHHHTT-S.GGGEEEEETTTTTS-......HTTT--EEEEE---STT--SS---HHHH CS
       NAGLU 193 ylaavskaiykalkaadpkavWvlqgWlfvsdkkfWtkerveallsavp.kdklliLDlfsekkpvwkrtksfegkpwiwcmlhnfGgrtglyGklekv 290
                 yl+++s+++ ++lkaadp+avW++q+Wlf  d++fW++ ++ a+ls+v+ ++++liLDlf+e++pvw+ t+s++gkpwiwc++h++Gg++glyG++ ++
  EEA22157.1 327 YLRNISRTTSQSLKAADPDAVWLMQSWLF-LDATFWNNVTICAYLSGVEnNSDMLILDLFAESQPVWQLTDSYYGKPWIWCQVHDYGGNMGLYGQIMNI 424
                 *****************************.899***************98899********************************************** PP

                 HHHHHHHHHT-S...EEEEEE--S-S-S-HHHHHHHHHGGG- CS
       NAGLU 291 aseiaealakkeksklvGiGltpEgiennpvvyelllelaws 332
                 +++ ++ala+  ++++vG+G t+E++e n++vy+lll++aws
  EEA22157.1 425 TENATAALAS--SGSMVGFGHTMESQEGNEIVYDLLLDQAWS 464
                 ********54..678**************************8 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 0.55
                 EEETTTTTS-......HTTT--EEEEE---STT--SS---HHHH CS
       NAGLU 247 iLDlfsekkpvwkrtksfegkpwiwcmlhnfGgrtglyGklekv 290
                 ++Dl +  ++v  +++ f+  +wi   +    g+t+l +  e  
  EEA22157.1 613 LIDLLQSLDTVLGTNECFQLAQWINKAVSRAHGNTTLAAYYEYN 656
                 56888888899999999999999999999999999988776654 PP

>> NAGLU_C  Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  223.4   1.6   6.2e-70   3.7e-66       1     251 [.     473     731 ..     473     743 .. 0.90

  Alignments for each domain:
  == domain 1  score: 223.4 bits;  conditional E-value: 6.2e-70
                 HHHHHHHHHHT...---HHHHHHHHHHHHTTTS---S---SS---GGGS-S-SS---SSTT..-----S-HHHHHHHHHHHHHHHHH...HTT-HHHHH CS
     NAGLU_C   1 WvkdYakrRyg...kedeeleeAweiLletvYnntkkeaegapesliearPslnakkassk..kaekkYdpkdllkawkllleaade...lkssetyry 91 
                 +++d+++ Ry      +++l +AweiL+ ++Ynnt+  ++++p+s++e++Ps++   +++   +++ +Ydp+ +++aw l +eaa     l+++++++y
  EEA22157.1 473 YFEDWVTVRYAgtqHVPQQLFDAWEILRWSAYNNTNLASSSVPKSILELEPSISGLLNREGhhPTTINYDPELVVEAWALTYEAALLelsLWDNPAFNY 571
                 89********99988999***********************************976655543466777****************987788********* PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHHTT..-HHHHHHHHHHHHHHHHHHHHHHTT-GGGBHHHHHHHHHHSST.T--HHHHHHHHHHHHTTTSSTT.TS CS
     NAGLU_C  92 Dlvdvtrqvlanlakelykelvaaykak..daeafkkaskkllelledlDellatreeflLgkWiedArslak.teeekelyelnArnqiTlWggpege 187
                 Dl+ +trqvl n++ + y+ l++ y+++  ++ a+ +a+++l++ll++lD++l+t+e f+L +Wi++A s a+ +++ +++ye+nArnqiTlW gp+ge
  EEA22157.1 572 DLIFLTRQVLVNAFIPRYELLISFYNNEnySVPAIVSAGRQLIDLLQSLDTVLGTNECFQLAQWINKAVSRAHgNTTLAAYYEYNARNQITLW-GPNGE 669
                 ***************************966677***********************************999984445688*************.799** PP

                 -TTTT----BTHHHHTHHHHHHHHHHHHHHHHTT-S---.......HHHHHHHHHT--T----S CS
     NAGLU_C 188 lnDYAnkeWsGLvkdYYlpRWklFvdalaealeegkefdeeelkkklfefeeaWveskkeypsk 251
                 ++DYA+k+W+GL+++YY+pRW++ vd+l+++     ++d ++l++ +f fe +W+++ +   ++
  EEA22157.1 670 ISDYASKQWAGLISSYYVPRWQILVDYLQSTC--PDSYDPTNLHQIIFTFESNWQQELDGQRNQ 731
                 ****************************9885..55677889************9988766555 PP

>> NAGLU_N  Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.4   0.0   1.2e-22   7.2e-19       2      81 ..      24     114 ..      23     115 .. 0.94

  Alignments for each domain:
  == domain 1  score: 67.4 bits;  conditional E-value: 1.2e-22
                 HHHHHHHHHH-GGGGGEEEEE.........--BTTB-EEEEE-SSS.-EEEEESSHHHHHHHHHHHHHHHS--B--T.T--B--.--SS-- CS
     NAGLU_N   2 avrelleRllpehaskfkfelv........eeksgkdvFeisskgg.kilIrGnsgvalasGlnwYLkyycgvhisw.ngdqlk.lPavLP 81 
                 ++++l++R++p+ha++f+f+          ++++ +d + +s+ ++ ++lI+Gns +al++Gl++YL ++++v+++w  g++l+ +P++LP
  EEA22157.1  24 GIYDLVKRRMPQHADSFQFSPLetvqnspdHTDQVTDQYVVSTPENgTVLIEGNSLSALSYGLHRYLADVAHVDMWWfIGNRLDiAPEELP 114
                 799*****************999999999655999*******98777*************************************99***** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (787 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       421  (0.0234815); expected 358.6 (0.02)
Passed bias filter:                      329  (0.0183502); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.59u 0.27s 00:00:00.86 Elapsed: 00:00:00.41
# Mc/sec: 5719.32
//
Query:       EEA22158.1  [L=493]
Description: monocarboxylate permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-11   43.8  41.4    1.5e-11   43.8  41.4    1.9  2  MFS_1     Major Facilitator Superfamily
    1.3e-07   32.1   0.0    2.7e-07   31.1   0.0    1.5  1  Ank_2     Ankyrin repeats (3 copies)
     0.0004   20.7   0.0       0.36   11.4   0.0    2.8  2  Ank       Ankyrin repeat
    0.00098   19.4   0.0       0.85   10.4   0.0    3.1  2  Ank_3     Ankyrin repeat
     0.0082   16.7   0.0       0.03   14.9   0.0    1.9  2  Ank_4     Ankyrin repeats (many copies)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.8  41.4   4.3e-15   1.5e-11      71     352 ..      50     311 ..      48     312 .. 0.79
   2 !    6.5   7.9   0.00096       3.4      88     171 ..     262     347 ..     257     351 .. 0.86

  Alignments for each domain:
  == domain 1  score: 43.8 bits;  conditional E-value: 4.3e-15
       MFS_1  71 lfalglllllfasslwlllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfl 169
                 l ++g+++++f   + + +v  v + +g +alf+a+++  + wf + +r++a+g+l +g+s+G ++ p++   l+  l + ++  i++++ l+++v++l
  EEA22158.1  50 LNVVGGWCIFF---SLFGWVNGVCTCIGDAALFTASLSTCSTWFYR-RRAFAFGVLLTGTSIGGVVMPIILEHLLGRLDFGWAIRICTFINLVLLVIAL 144
                 56788788886...335899999***********************.***********************************************88755 PP

       MFS_1 170 lllpeepperkrkspkeeekgtgpaplvpawkallkdpvlwillialllfffgfsglltllpl....ylqevlglsglllaglllallalvgailalla 264
                   ++ + p+++++ +               w +l+  +    + + +l++++++++l ++lp+          g+s   lag+l+++l + +++++++ 
  EEA22158.1 145 PTVTSRLPPHPKPVSL--------------WYYLRPLKG---IRFLMLSAGCALFYLGMYLPFnfiiVQALYEGMS-PALAGYLIPILNATSLFGRIIP 225
                 5555555555555444..............445554442...3444444444555555555553211135555666.79******************** PP

       MFS_1 265 grlsdrlgrrrrlllallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfntagslggalg 352
                 g  +d +gr ++++ +++++ +++l+l l + + +a++ +l++ l+Gf++g + +++ al+++    +e g  sg   ++ +++++++
  EEA22158.1 226 GIAADMVGRFNTMVAMCAFAGIIVLALWLPGRA-NAPI-ILFSGLYGFASGAFISLIPALTAQISDIREIGVRSGTLWLTVAIAALVA 311
                 ***************************999999.4444.4478889999999999999999999888999999998888888888776 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.00096
       MFS_1  88 llvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllgglla..sslgWravfyilaivsllafvlflll 171
                 ++++  l G+++ga+++++ al+a+++  +e g   g l ++++++a+++ ++gg++   + + ++ + +++++v+l++  +f++ 
  EEA22158.1 262 IILFSGLYGFASGAFISLIPALTAQISDIREIGVRSGTLWLTVAIAALVASPIGGAMEvrDDGAFEQLQIFAGVVMLVGTSCFGVA 347
                 7888999*******************************************999998853555558888899999988887766655 PP

>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.1   0.0   7.6e-11   2.7e-07      11      77 ..     412     488 ..     403     492 .. 0.84

  Alignments for each domain:
  == domain 1  score: 31.1 bits;  conditional E-value: 7.6e-11
       Ank_2  11 elvklLl.egadpn.k...ngktaLhyAakngnleivklLleh...ad.ndgr..tpLhyAarsghleivklLl.ekga 77 
                  +vklLl  gad+n +   +g +aL++A  +g++ei+klLl++   ++ + g+  ++L +A+  g++e +k Ll ekg 
  EEA22158.1 412 RFVKLLLdRGADVNfQggyFG-NALQVASFKGHKEIMKLLLDNgagINiQGGHfvNALKAAS-AGNQEGIKGLLlEKGM 488
                 489***********9556788.********************887866767777899*9998.7999****66658864 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.2   0.0    0.0043        15      16      29 ..     412     426 ..     406     428 .. 0.85
   2 !   11.4   0.0    0.0001      0.36       5      30 ..     434     460 ..     433     461 .. 0.88

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0043
                 HHHHHHH.TTTSTTC CS
         Ank  16 riiklLL.hGAnlna 29 
                 r +klLL +GA++n 
  EEA22158.1 412 RFVKLLLdRGADVNF 426
                 579****779***95 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.0001
                 HHHHHHHHTTHHHHHHHH.TTTSTTCB CS
         Ank   5 PLHlAatngkkriiklLL.hGAnlnal 30 
                 +L +A+  g+k+i klLL +GA +n++
  EEA22158.1 434 ALQVASFKGHKEIMKLLLdNGAGINIQ 460
                 68899999**********889999986 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.5   0.0    0.0094        34      13      30 ..     411     425 ..     406     426 .. 0.85
   2 !   10.4   0.0   0.00024      0.85       5      31 .]     434     459 ..     432     459 .. 0.92

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0094
       Ank_3  13 gnleivkfLlenkgadvn 30 
                 g++  vk+Ll+ +gadvn
  EEA22158.1 411 GRF--VKLLLD-RGADVN 425
                 555..9*****.*****9 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00024
       Ank_3   5 pLhlAarsgnleivkfLlenkgadvna 31 
                 +L +A   g+ ei+k+Ll+ +ga +n+
  EEA22158.1 434 ALQVASFKGHKEIMKLLLD-NGAGINI 459
                 7999999************.8***996 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   8.4e-06      0.03      17      55 .]     414     451 ..     409     451 .. 0.96
   2 ?   -2.5   0.0       2.4   8.5e+03       7      24 ..     469     487 ..     467     488 .. 0.75

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 8.4e-06
       Ank_4  17 vrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 v+lLl++gad+n q  ++  +al+ A  +g++ei klLl
  EEA22158.1 414 VKLLLDRGADVNFQ-GGYFGNALQVASFKGHKEIMKLLL 451
                 89************.99999******************8 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 2.4
       Ank_4   7 yaaisgrlelvr.lLlekg 24 
                 +aa++g+ e ++ lLlekg
  EEA22158.1 469 KAASAGNQEGIKgLLLEKG 487
                 5777888887777999988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (493 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       568  (0.0316805); expected 358.6 (0.02)
Passed bias filter:                      318  (0.0177366); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.42
# Mc/sec: 3546.31
//
Query:       EEA22159.1  [L=512]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.3e-12   45.7   0.5    1.7e-11   44.6   0.5    1.6  1  CBM_4_9       Carbohydrate binding domain


Domain annotation for each model (and alignments):
>> CBM_4_9  Carbohydrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.6   0.5   9.2e-16   1.7e-11       2     130 ..      49     178 ..      48     184 .. 0.82

  Alignments for each domain:
  == domain 1  score: 44.6 bits;  conditional E-value: 9.2e-16
                 BCCCECTSTTSTTTTSEECSSTCEEEEECGCSSSSEEEEEESCSSTTCEEEEEEECCS-TT-EEEEEEEEEESSTS.....EEEEEEEEEESSTTSCTC CS
     CBM_4_9   2 nllkngtFedgglegWkargkssgkasvdvsyngtyslkvsgrgetwdgqaiditirlekgktYtvsfwvkassgk.....srtikvkigdtdadgany 95 
                 nl++n++Fed g + W +  + sg+++ +++++g+y+l +++  ++  + +++  + ++ g+tYt s++ ++s+ +     s+ ++  +   ++  +  
  EEA22159.1  49 NLIVNPSFED-GFSSWGFASGTSGSVVSGHASDGSYYLAATDIQTHSGIMIYQYVTGFKAGMTYTASLDWSLSALSsgisqSCHLYWYMDSYGS--TIG 144
                 89********.******99998899999999************998888999999*****************9999999545555555444444..344 PP

                 EEEEEEEEEESTSEEEEEEEEE-SSCSCCEEEEEE CS
     CBM_4_9  96 devadekvelkgewktlegtFtipkstdenvelyv 130
                 ++ a+  ++++ +w+ +   +t++ + +  +e+y 
  EEA22159.1 145 STSAT-LTTNSMDWTHFATVYTPSTDGTHLLEIYA 178
                 44444.88999*************66666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (512 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1040  (0.0580066); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.76u 0.30s 00:00:01.06 Elapsed: 00:00:00.47
# Mc/sec: 3283.42
//
Query:       EEA22160.1  [L=231]
Description: GPI anchored protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (231 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1216  (0.0678231); expected 358.6 (0.02)
Passed bias filter:                      350  (0.0195214); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.43
# Mc/sec: 1605.80
//
Query:       EEA22161.1  [L=232]
Description: GPI anchored protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (232 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1219  (0.0679904); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 1486.31
//
Query:       EEA22162.1  [L=404]
Description: RNA-3'-phosphate cyclase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.8e-30  104.9   0.0    5.8e-30  103.9   0.0    1.6  1  RTC_insert  RNA 3'-terminal phosphate cyclase (RTC), insert d
    7.7e-28   97.2   0.0    9.8e-28   96.9   0.0    1.0  1  RTC         RNA 3'-terminal phosphate cyclase


Domain annotation for each model (and alignments):
>> RTC_insert  RNA 3'-terminal phosphate cyclase (RTC), insert domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.9   0.0   6.5e-34   5.8e-30       2     103 .]     206     319 ..     205     319 .. 0.87

  Alignments for each domain:
  == domain 1  score: 103.9 bits;  conditional E-value: 6.5e-34
                 S----SEEEEEEEEESS-THHHHHHHHHHHHHHTTTSSEEEEEEE.EE-CGG...C-SS-.........EEEEEEEEE-T.TS-EEEEEEE..E-TT-- CS
  RTC_insert   2 drGrvkrirGvafaarvspsvanrmveaargvLnkllpdvyiytdvvkegke...sgksp.........GfgisLvaetttegvllgaeal..gekgvp 86 
                 ++Gr+k +rGva++++vs+s+++rm+++argvLn l+pd yi++d+  +++     +ks+         Gfg++Lvae++t g+l++a+ +   ++gvp
  EEA22162.1 206 NPGRIKTVRGVAYSTGVSASNNARMIQTARGVLNPLVPDTYIASDA-SSAPLvpaPEKSNpggkkkvglGFGLFLVAESST-GCLFSADIAspPDGGVP 302
                 89*******************************************4.2222234433333688888889***********6.*********88889*** PP

                 HHHHHHHHHHHHHHHHH CS
  RTC_insert  87 pedvGeeaaeeLleeie 103
                 ped+G+++a++Lle+i+
  EEA22162.1 303 PEDIGKQCAYQLLETIS 319
                 **************995 PP

>> RTC  RNA 3'-terminal phosphate cyclase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   96.9   0.0   1.1e-31   9.8e-28       8     192 ..      15     341 ..       9     370 .. 0.89

  Alignments for each domain:
  == domain 1  score: 96.9 bits;  conditional E-value: 1.1e-31
                 HHHHHHHHHHHH---EEEESTTTTSSS.-S--HHHHHHHHHHHHHHT-EEE--STT-SEEEEE------SEEEEEEESSE............BHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............xxxxxxx RF
         RTC   8 iLRtalaLsaltgkpvrIenIRanRkk.PGLraqhltavrllakitnaevegaeigsteleFkPgeikageyevdigtAG............sitlllq 93 
                  +  +l+L++ltg+pv+I++IR+n ++ PGL++++++++rll++itn++    +   t + +kPg i+++   + +++ G            +i+++l 
  EEA22162.1  15 NFTYRLVLATLTGRPVQISQIRSNSPSnPGLAPHEISFLRLLEAITNGSQMEISYSGTIVVYKPGLITGSAAGLGTTSNGvikheipsnctrGISYFLI 113
                 67789******************99988*********************666665555*******888888888888888999999999999******* PP

                 HHHHHHTTSSS-EEEEEEE...BSBB..TTS--HHHHHHTHHHHHHHHT.-E.EEEEEEE-...-BTTTB-.EEEEEEEE-.-S.---EB......... CS
                 xxxxxxxxxxxxxxxxxxx...xxxx..xxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxx...xxxxxxx.xxxxxxxxxxxx.xxxxx......... RF
         RTC  94 tllplllfakkpseltlkG...gTnv..saapsvdylktvllpllkrfgvle.lelelkkr...GfypkGg.Gevelevepskk.lkpie......... 172
                 +l++l++f+k+p+++ ++G   +T +  + ++s+d +++++lpl+k fg+++ +el++ +r   G+  kGg Gev+l    + + +k+++         
  EEA22162.1 114 PLCLLAPFSKAPMNVLFTGpgvITSAtpTGDISADAVRMAILPLYKMFGIFNnIELRIMQRsnpGHNGKGGgGEVQLVFGHQVRlPKTLHfmnpgrikt 212
                 ******************9766576522469******************98889*999977333666555559****9965555466666888****** PP

                 ................................................................................................... CS
                 ................................................................................................... RF
         RTC 173 ................................................................................................... 172
                                                                                                                    
  EEA22162.1 213 vrgvaystgvsasnnarmiqtargvlnplvpdtyiasdassaplvpapeksnpggkkkvglgfglflvaesstgclfsadiasppdggvppedigkqca 311
                 *************************************************************************************************** PP

                 ..........BSS-HHHHHHHHHHHHHHT. CS
                 ..........xxxxxxxxxxxxxxxxxxxx RF
         RTC 173 ..........acvDehlqdqlilfmaLakg 192
                           +cv +  +  ++++ma+ ++
  EEA22162.1 312 yqlletiskgGCVAPAAAPTMLMLMAMGSE 341
                 ***************************984 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (404 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       270  (0.0150594); expected 358.6 (0.02)
Passed bias filter:                      238  (0.0132746); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2749.67
//
Query:       EEA22163.1  [L=195]
Description: 3-hydroxyanthranilate 3,4-dioxygenase Bna1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-52  177.5   0.0    1.4e-52  177.3   0.0    1.1  1  3-HAO         3-hydroxyanthranilic acid dioxygenase
    0.00025   20.7   0.0    0.00047   19.8   0.0    1.6  1  Cupin_2       Cupin domain
    0.00087   18.9   0.1     0.0018   17.9   0.1    1.5  1  Cupin_1       Cupin
  ------ inclusion threshold ------
      0.024   14.5   0.0      0.036   14.0   0.0    1.3  1  AraC_binding  AraC-like ligand binding domain
       0.08   13.1   0.4       0.08   13.1   0.4    1.8  2  Zn-ribbon_8   Zinc ribbon domain


Domain annotation for each model (and alignments):
>> 3-HAO  3-hydroxyanthranilic acid dioxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  177.3   0.0     4e-56   1.4e-52       5     150 ..       4     162 ..       1     163 [. 0.91

  Alignments for each domain:
  == domain 1  score: 177.3 bits;  conditional E-value: 4e-56
                 TEEEHHHHHHHCGGGCSTTT-EEEEE....ESSEEEEEE-SSB--S-EEE-SS-EEEEEEES-EEEEEEETTCCC....EEEE-TTEEEEE-TT--EEE CS
       3-HAO   5 tainiekwvkenrellkPPvcnkclh....kdglkvlivGGPnerkdyhleegeeffyqkkGdmvlkvldegkar....divireGeifllParvphsP 95 
                 +++ni+kw++ n +ll+PPv+n+c++    + g++v+ivGGPn+r+dyh++ ++effyq +G+m+lk +d ++      d++i+eG +fllPa+ ph P
  EEA22163.1   4 PSLNIPKWLETNSHLLQPPVNNYCVYhpsnSAGYTVMIVGGPNARTDYHINSTPEFFYQYRGSMLLKTVDTATSPptfvDVPIHEGSLFLLPANTPHCP 102
                 579*********************973333579*************************************999878888******************** PP

                 EE-TT-EEEEEEE---TTS-EEEEEESTT..TS...SEEEEEEE-SSSCCCHHHHHHHHH CS
       3-HAO  96 qrfadsvGlvvererleteldklryyvge..sn...qvlfekelqlkdletdlkpvikef 150
                 +rf d++G+v+e+ r e+ +d++r+y+ +  ++   +++fek + ++dl+t++k+v++ef
  EEA22163.1 103 VRFKDTIGVVLEQPRAEGAEDAMRWYCMSeeCKgkgTIVFEKRFVCTDLGTQVKEVVEEF 162
                 **************************9752255333579*******************99 PP

>> Cupin_2  Cupin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.0   1.3e-07   0.00047       7      57 ..      42     102 ..      36     130 .. 0.84

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 1.3e-07
                 TTE.EEEEECSSSEE.EEEEEEESEEEEE.ECTE.......EEEEETTEEEEE-TT-EEEE CS
     Cupin_2   7 pGe.sapshrHpged.effyVleGegelt.vdge.......eveleaGdsvyfpagtpHrf 57 
                  G+  a   +H +++ effy  +G + l+ vd         +v++++G +++ pa+tpH  
  EEA22163.1  42 VGGpNARTDYHINSTpEFFYQYRGSMLLKtVDTAtspptfvDVPIHEGSLFLLPANTPHCP 102
                 4555666677777777*********99999**777789999******************87 PP

>> Cupin_1  Cupin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.1   5.1e-07    0.0018      31      98 ..      34     101 ..      23     113 .. 0.91

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 5.1e-07
                 STEEEEEEEE.TTEEEEEEEESSS-EEEEEEESEEEEEEEETTSS.EEEEEE.EETTEEEEE-TT-EEE CS
     Cupin_1  31 lgisaarvdlepgglllPhyhpnateiayvlqGegrvgfvvpgngnrdfhkk.lreGdvfvvPaglvhf 98 
                 +++ +++++  p++    h++ +++e +y   G++++ +v ++ +  +f  + ++eG +f +Pa+ +h+
  EEA22163.1  34 SAGYTVMIVGGPNARTDYHIN-STPEFFYQYRGSMLLKTVDTATSPPTFVDVpIHEGSLFLLPANTPHC 101
                 667788888899999******.**********************************************7 PP

>> AraC_binding  AraC-like ligand binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   9.9e-06     0.036       9      59 ..      42     100 ..      34     101 .. 0.92

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 9.9e-06
                   TTSTT-SEEEETT-SEEEEEEEEE-EEE.EETTEE.......EEE-TT-EEEE-TTS-E CS
  AraC_binding   9 agypdhsfpphvhdeyvihyvteGtgrl.rlngrt.......ydlgpGdlfLlppgepH 59 
                    g p+ ++++h  ++ ++ y  +G+  l +++  t       + +++G+lfLlp ++pH
    EEA22163.1  42 VGGPNARTDYHINSTPEFFYQYRGSMLLkTVDTATspptfvdVPIHEGSLFLLPANTPH 100
                   57799999********************8888888************************ PP

>> Zn-ribbon_8  Zinc ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.3       3.3   1.2e+04      27      30 ..      98     102 ..      95     103 .. 0.60
   2 ?   13.1   0.4   2.2e-05      0.08       6      38 ..     146     181 ..     145     182 .. 0.75

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 3.3
  Zn-ribbon_8  27 ta.CP 30 
                  t+ CP
   EEA22163.1  98 TPhCP 102
                  55588 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 2.2e-05
  Zn-ribbon_8   6 YrCeeCghefe.vlqsis.dapltaCPeCgs.evrr 38 
                  + C++ g++   v+ ++  d+++ +C +Cg+ ++ r
   EEA22163.1 146 FVCTDLGTQVKeVVEEFGaDEKKRTCEKCGAvAAVR 181
                  7899967666537777777777777******88877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (195 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       568  (0.0316805); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 1407.22
//
Query:       EEA22164.1  [L=723]
Description: Noc1p protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.6e-16   57.6   1.5    1.8e-15   56.7   0.9    1.8  1  CAP_GLY        CAP-Gly domain
    4.1e-09   36.1  10.7      5e-05   23.1   0.9    2.7  2  CLIP1_ZNF      CLIP1 zinc knuckle
     0.0049   16.9  16.8     0.0049   16.9  16.8    3.6  3  TPR_MLP1_2     TPR/MLP1/MLP2-like protein
      0.007   16.8  10.9       0.02   15.3   1.5    3.4  3  NPV_P10        Nucleopolyhedrovirus P10 protein
  ------ inclusion threshold ------
      0.031   14.7  25.2      0.025   15.1   6.9    3.4  3  Spectrin       Spectrin repeat
      0.043   14.4   0.5         18    6.0   0.1    2.8  2  Fe-S_assembly  Iron-sulphur cluster assembly
      0.043   13.2  15.0      0.041   13.3   5.5    3.2  3  FAM76          FAM76 protein
      0.066   13.3  14.0       0.63   10.1   2.9    3.3  3  DUF1664        Protein of unknown function (DUF1664)
       0.13   10.9  21.9      0.018   13.7   9.7    2.6  3  AAA_13         AAA domain
       0.14   11.7  13.2      0.071   12.7   9.9    2.0  2  DUF4795        Domain of unknown function (DUF4795)
       0.18   12.1   1.1        2.2    8.6   0.1    2.9  3  Ribosomal_S15  Ribosomal protein S15
       0.37   11.0  37.0         11    6.1  16.9    3.5  3  ATG16          Autophagy protein 16 (ATG16)
       0.51   11.0  27.6        2.8    8.6   8.1    4.0  3  SlyX           SlyX
       0.65    8.8  27.4       0.33    9.8  16.9    3.0  3  DUF812         Protein of unknown function (DUF812)
       0.68   10.4  31.0       0.27   11.7  16.9    3.3  3  Fez1           Fez1
        0.8   10.8   0.1        0.8   10.8   0.1    3.4  2  DUF5320        Family of unknown function (DUF5320)
       0.81   10.0  20.6        1.5    9.2   3.2    4.1  3  BLOC1_2        Biogenesis of lysosome-related organelles comp
       0.95   10.0  24.3          3    8.4   0.3    4.8  4  DUF16          Protein of unknown function DUF16
        1.2    9.2   7.5        3.3    7.8   3.1    2.8  3  Baculo_PEP_C   Baculovirus polyhedron envelope protein, PEP, 
        1.2    7.9  33.9       0.77    8.6  11.6    3.0  2  Spc7           Spc7 kinetochore protein
        1.8    6.0  25.6        3.3    5.1  25.6    1.3  1  DUF3584        Protein of unknown function (DUF3584)
        1.8    8.9   3.3         28    5.2   0.2    2.4  2  C1_2           C1 domain
        2.1    6.4  21.2       0.87    7.7   7.6    2.7  3  EzrA           Septation ring formation regulator, EzrA
        2.5    6.6  11.7        3.6    6.1  11.7    1.1  1  Peptidase_S46  Peptidase S46
        2.8    7.7  11.0        2.9    7.7   3.6    2.6  2  SKA1           Spindle and kinetochore-associated protein 1
        3.9    7.6  34.1        2.3    8.4   3.7    4.5  3  TolA_bind_tri  TolA binding protein trimerisation
        7.6    6.6  34.1       0.29   11.1   2.4    5.2  5  TMF_DNA_bd     TATA element modulatory factor 1 DNA binding
        7.8    5.8  25.8    8.7e+03   -4.2  25.8    2.8  0  DUF4407        Domain of unknown function (DUF4407)
        8.7    6.1  22.4       0.68    9.7   4.7    3.0  3  DUF724         Protein of unknown function (DUF724)
         10    5.9  23.9        6.4    6.6   7.0    3.6  3  Phage_GP20     Phage minor structural protein GP20


Domain annotation for each model (and alignments):
>> CAP_GLY  CAP-Gly domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.7   0.9     3e-18   1.8e-15       1      63 [.       9      75 ..       9      77 .. 0.89

  Alignments for each domain:
  == domain 1  score: 56.7 bits;  conditional E-value: 3e-18
     CAP_GLY  1 vgdrvklkegrrGvvryvGpvpfakgewvGveldep...nGkndGsvkgkrYFe.ckpnrGvFvrpe 63
                vgd+v++++g +G+vr++G v++++g ++G+el  +   +Gkn+G v+g+ YF+ + p+ G+Fv+ +
  EEA22164.1  9 VGDQVNVPGGMYGTVRFLGVVDGKPGRFAGIELATEhaaRGKNNGDVDGRSYFNtTVPGAGIFVPIN 75
                89***999*************************6433569*************9455*******976 PP

>> CLIP1_ZNF  CLIP1 zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   3.1   6.7e-06     0.004       2      15 ..     587     600 ..     587     602 .. 0.89
   2 !   23.1   0.9   8.4e-08     5e-05       2      17 .]     704     719 ..     704     719 .. 0.98

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 6.7e-06
   CLIP1_ZNF   2 pYCdnCEvFGHdTe 15 
                 ++C++CE  GHd+ 
  EEA22164.1 587 LWCEICETNGHDIL 600
                 7***********86 PP

  == domain 2  score: 23.1 bits;  conditional E-value: 8.4e-08
   CLIP1_ZNF   2 pYCdnCEvFGHdTedC 17 
                 ++C++CE++GH+ +dC
  EEA22164.1 704 KWCALCERDGHESIDC 719
                 7*************** PP

>> TPR_MLP1_2  TPR/MLP1/MLP2-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9  16.8   8.1e-06    0.0049       8     117 ..     206     313 ..     202     316 .. 0.91
   2 ?    1.4   8.9      0.51   3.1e+02      25      98 ..     319     389 ..     311     409 .. 0.62
   3 ?    2.3   0.1      0.28   1.7e+02      56      90 ..     432     466 ..     426     472 .. 0.55

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 8.1e-06
  TPR_MLP1_2   8 eeikslkeekeeaeaklqklqedlekqaeiakeaqqkYerelvkhaedvkelqalreelnelkaeiaelkaeaesakaeleeseesweeqkeelekels 106
                 +ei++l+e+++++e++lq+  ++l  qa+ ++e qq+  +   +  + ++  ++lre+ +++ +  ae+ + + + +++l++ e + +e++  +ek+l+
  EEA22164.1 206 QEIQALQEKIKSLEEELQARDRQLDDQASVLTELQQSITELEGQDGASIR--AQLREKNEKIAQLTAEFDSHRADFRSTLDTLEVAATETERVYEKRLD 302
                 79**********************************88876666666665..5999999999************************************* PP

  TPR_MLP1_2 107 elekriedlne 117
                 el ++  +l++
  EEA22164.1 303 ELMQQNRELQD 313
                 **999999985 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.51
  TPR_MLP1_2  25 qklqedlekqaeiakeaqqkYerelvkhaedvkelqalreelnelkaeiaelkaeaesakaeleeseesweeqk 98 
                 +++  +l++ +e+++e ++  e      ae+  e++ lr e+++++ e   lk+e+e+  a+l+ +e  w+ ++
  EEA22164.1 319 EAVALQLKQLEELVSELEEGLEDARRGEAEARGEVEFLRGEVERAQLE---LKQEREKSAAALKDAEGRWNGRE 389
                 555556666666666666666666666666666666677666666654...55666666777777777776554 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.28
  TPR_MLP1_2  56 vkelqalreelnelkaeiaelkaeaesakaelees 90 
                 ++ +++l e+++el+  ++   ++ ++++ el ++
  EEA22164.1 432 TERISQLEERIKELEGVAEIRSSRIDELQRELGQN 466
                 55555555555555555555555555555555554 PP

>> NPV_P10  Nucleopolyhedrovirus P10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   1.5   3.3e-05      0.02      17      61 ..     205     246 ..     203     248 .. 0.91
   2 ?   -0.2   0.0       2.4   1.4e+03       9      36 ..     254     281 ..     252     295 .. 0.74
   3 ?    4.8   0.9     0.066        39      18      59 ..     299     340 ..     294     344 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 3.3e-05
     NPV_P10  17 ddkVdalqqqvddvqenlpdvtelnekLdaqsaqLaeletkvenI 61 
                 ++ ++alq+++++++e+l+       +Ld+q+  L+el++++++ 
  EEA22164.1 205 SQEIQALQEKIKSLEEELQA---RDRQLDDQASVLTELQQSITEL 246
                 6889***************9...459**************99975 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 2.4
     NPV_P10   9 IradikavddkVdalqqqvddvqenlpd 36 
                 Ira  ++ ++k+  l ++ d+ +++++ 
  EEA22164.1 254 IRAQLREKNEKIAQLTAEFDSHRADFRS 281
                 7888888888888888888777776654 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.066
     NPV_P10  18 dkVdalqqqvddvqenlpdvtelnekLdaqsaqLaeletkve 59 
                 +++d l qq  ++q+  +dv+ +  +L ++ + + ele+ +e
  EEA22164.1 299 KRLDELMQQNRELQDRGEDVEAVALQLKQLEELVSELEEGLE 340
                 567778888888888888888888888888887777777655 PP

>> Spectrin  Spectrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.1   6.9   4.2e-05     0.025      33      99 ..     205     275 ..     197     281 .. 0.87
   2 ?    5.6   4.8     0.038        22      33      96 ..     276     339 ..     263     345 .. 0.61
   3 ?    3.9   0.5      0.12        73      42     103 ..     389     456 ..     360     458 .. 0.73

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 4.2e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHH....HHHHHHHHTTHTTHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Spectrin  33 leevqallkkhkaleaelaaqqervkaln....elaeklldeghsaseeieerleelnerWeeLkelaaer 99 
                  +e+qal++k k le+el+a+++++++      el++++++ ++++ + i+++l e ne+ ++L +  +++
  EEA22164.1 205 SQEIQALQEKIKSLEEELQARDRQLDDQAsvltELQQSITELEGQDGASIRAQLREKNEKIAQLTAEFDSH 275
                 589*******************99997555566**************************999998776655 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.038
                 HHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHHHHHHTTHTTHHHHHHHHHHHHHHHHHHHHHH CS
    Spectrin  33 leevqallkkhkaleaelaa.qqervkalnelaeklldeghsaseeieerleelnerWeeLkela 96 
                  ++ ++ l++++    e +  +++r+++l+++ ++l+d+ +++ e++  +l++l+e   eL+e +
  EEA22164.1 276 RADFRSTLDTLEVAATETERvYEKRLDELMQQNRELQDR-GEDVEAVALQLKQLEELVSELEEGL 339
                 445555555555566666655777777777777777666.4677777777777777777776654 PP

  == domain 3  score: 3.9 bits;  conditional E-value: 0.12
                 HHHHHHHHHHHHHHHHHHHH..HHHHHH.HHTT...HTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
    Spectrin  42 khkaleaelaaqqervkaln..elaekl.ldeg...hsaseeieerleelnerWeeLkelaaerkqkL 103
                 ++++  +e++  +  + +l   e+  ++  ++g   +++  + +er+++l+er +eL+  a+ r  ++
  EEA22164.1 389 ELEQKDDEIRGLKAIIHSLSrgEVNPAMfNTNGtshGDSRSHDTERISQLEERIKELEGVAEIRSSRI 456
                 6677777777777777777777777777555556656667999***************9999998765 PP

>> Fe-S_assembly  Iron-sulphur cluster assembly
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.1      0.03        18       9      44 ..     218     253 ..     213     271 .. 0.87
   2 ?    5.8   0.0     0.036        22      12      43 ..     310     341 ..     306     350 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.03
  Fe-S_assembly   9 IAiaLyekypdvdpltvrFtdLhewvleLpefdddp 44 
                    + ++L+ + +++d +    t+L++ ++eL++ d+ +
     EEA22164.1 218 LEEELQARDRQLDDQASVLTELQQSITELEGQDGAS 253
                    5689999999****9999*************99876 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.036
  Fe-S_assembly  12 aLyekypdvdpltvrFtdLhewvleLpefddd 43 
                    +L+++ +dv+ + ++ ++L+e v eL+e  +d
     EEA22164.1 310 ELQDRGEDVEAVALQLKQLEELVSELEEGLED 341
                    799***********************765444 PP

>> FAM76  FAM76 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   5.5   6.8e-05     0.041     221     286 ..     208     273 ..     204     278 .. 0.93
   2 ?    6.5   1.1    0.0077       4.6     241     295 ..     257     311 ..     250     317 .. 0.58
   3 ?    3.7   0.2     0.055        33     184     254 ..     395     468 ..     339     478 .. 0.53

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 6.8e-05
       FAM76 221 vtqLkeeiaslkkqleqkdqellekdkkitelkaellekekelreklkelekeakekieklekkir 286
                 ++ L+e+i+sl+ +l+ +d +l ++   +tel+   +e e +    ++++ +e +eki +l+++  
  EEA22164.1 208 IQALQEKIKSLEEELQARDRQLDDQASVLTELQQSITELEGQDGASIRAQLREKNEKIAQLTAEFD 273
                 889*********************************************************998765 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0077
       FAM76 241 ellekdkkitelkaellekekelreklkelekeakekieklekkirellkevael 295
                 +l ek+ ki++l+ae  +++++ r+ l +le  a+e+    ek+  el++++ el
  EEA22164.1 257 QLREKNEKIAQLTAEFDSHRADFRSTLDTLEVAATETERVYEKRLDELMQQNREL 311
                 5566666666666666666666666666665555555555555555555555444 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.055
       FAM76 184 s.....rlevskleeeklaeekesnetskksldsnssdhlvavtqLkeeiaslkkqleqkdqellekdkkitelka 254
                       +  + +l+ ++ ++ +  n++ +++ ds+ s     ++qL+e+i++l+   e + + + e ++++ + ++
  EEA22164.1 395 DeirglKAIIHSLS-RGEVNPAMFNTNGTSHGDSR-SHDTERISQLEERIKELEGVAEIRSSRIDELQRELGQNRS 468
                 11112122222222.22233333333333344444.5556799**********99999999999999999887665 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   2.8    0.0018       1.1      55     115 ..     209     270 ..     204     274 .. 0.83
   2 ?   10.1   2.9     0.001      0.63      48     122 ..     263     337 ..     252     340 .. 0.93
   3 ?    0.5   0.0         1     6e+02      61      96 ..     428     463 ..     415     470 .. 0.69

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.0018
     DUF1664  55 eslaatkrhLssridrvdkkldeqkeiskeikeevtevr.edlseigedvesvkeavegles 115
                 ++l++  + L+++++  d++ld+q+ + +e+++ +te++ +d ++i+ ++++ +e + +l +
  EEA22164.1 209 QALQEKIKSLEEELQARDRQLDDQASVLTELQQSITELEgQDGASIRAQLREKNEKIAQLTA 270
                 56777778899999999*********************835788999999999998888876 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.001
     DUF1664  48 kqleqvseslaatkrhLssridrvdkkldeqkeiskeikeevtevredlseigedvesvkeavegleskleriee 122
                 +++ q+ ++  + + ++ s +d+++    e++++ ++  +e+++ +++l++ gedve+v    ++le+ ++++ee
  EEA22164.1 263 EKIAQLTAEFDSHRADFRSTLDTLEVAATETERVYEKRLDELMQQNRELQDRGEDVEAVALQLKQLEELVSELEE 337
                 678899999*************************************************************99986 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 1
     DUF1664  61 krhLssridrvdkkldeqkeiskeikeevtevredl 96 
                 + h ++ri +++++++e + +++  ++ ++e++++l
  EEA22164.1 428 RSHDTERISQLEERIKELEGVAEIRSSRIDELQREL 463
                 556667777777777777766666666666666665 PP

>> AAA_13  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   4.0     0.045        27     409     452 ..     206     249 ..     201     266 .. 0.74
   2 ?   13.7   9.7   3.1e-05     0.018     287     455 ..     238     406 ..     237     415 .. 0.82
   3 ?    1.0   0.2      0.22   1.3e+02     433     468 ..     429     464 ..     411     470 .. 0.60

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.045
      AAA_13 409 seldeykkkykklekaieklekelkeeeaelkkleeeikeLekq 452
                 +e++++++k+k+le++++  +++l+++++ l +l++ i eLe q
  EEA22164.1 206 QEIQALQEKIKSLEEELQARDRQLDDQASVLTELQQSITELEGQ 249
                 57777888888888888888888888888888888888887755 PP

  == domain 2  score: 13.7 bits;  conditional E-value: 3.1e-05
      AAA_13 287 rLekliekvesk.kselleklkavsde.asensafeedkeelkaeaealeeqLkglqraleaKrkepfk.svelesvkakiesikklvaeineliakhN 382
                 +L++ i+++e++  +++ ++l +  ++ a++  +f++ ++++++ +++le + ++ +r+ e++ +e+++ + el++  +++e++  ++++++el+++  
  EEA22164.1 238 ELQQSITELEGQdGASIRAQLREKNEKiAQLTAEFDSHRADFRSTLDTLEVAATETERVYEKRLDELMQqNRELQDRGEDVEAVALQLKQLEELVSELE 336
                 5788888886541567778888888866888899999*****************************9997899************************** PP

      AAA_13 383 ekvanleeekeeakkklelhlveeleseldeykkkykklekaieklekelkeeeaelkkleeeikeLekqlrd 455
                 e  ++  + ++ea+ ++e  + e  +++l e+k++ +k ++a++++e +   + +el+++++ei+ L++ + +
  EEA22164.1 337 EGLEDARRGEAEARGEVEFLRGEVERAQL-ELKQEREKSAAALKDAEGR--WNGRELEQKDDEIRGLKAIIHS 406
                 *****************987766555555.5777777777777777744..4456677777777777766655 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 0.22
      AAA_13 433 keeeaelkkleeeikeLekqlrdekpaaeeinkeLk 468
                 + +++++ +lee+ikeLe   +     ++e+ +eL 
  EEA22164.1 429 SHDTERISQLEERIKELEGVAEIRSSRIDELQRELG 464
                 445555555555555555555555555555555543 PP

>> DUF4795  Domain of unknown function (DUF4795)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   9.9   0.00012     0.071      14     157 ..     206     379 ..     178     386 .. 0.70
   2 ?   -1.0   0.1       1.9   1.2e+03      23      48 ..     435     460 ..     422     469 .. 0.57

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 0.00012
     DUF4795  14 eaieklqeelekleekvkelekrledkekklealkkqieelekvkadkeeveeelaekadke.aLatkvsrdq....................fDeakk 91 
                 ++i+ lqe++++lee+ +  + +l d+ + l  l+++i ele + +    +  +l+ek  k  +L +  +                        +++++
  EEA22164.1 206 QEIQALQEKIKSLEEELQARDRQLDDQASVLTELQQSITELEGQDGA--SIRAQLREKNEKIaQLTAEFDSHRadfrstldtlevaatetervYEKRLD 302
                 67999999999999999999*********************998766..88888888888752677777666667555555544444444444444444 PP

     DUF4795  92 eLekmleellekleeqeealkkaldtLq.............eelkekld.........rlelepLkeqleerlkelqkelqeameked 157
                 eL ++ +el ++ e           +++             +el+e l+         r e+e L+ ++e+   el++e ++ +++++
  EEA22164.1 303 ELMQQNRELQDRGE-----------DVEavalqlkqleelvSELEEGLEdarrgeaeaRGEVEFLRGEVERAQLELKQEREKSAAALK 379
                 44444455555433...........333333333344344478888888888898999999999999999888888866555555443 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 1.9
     DUF4795  23 lekleekvkelekrledkekklealk 48 
                 +++lee+ kele+  e +++ ++ l+
  EEA22164.1 435 ISQLEERIKELEGVAEIRSSRIDELQ 460
                 34444444444444444444444443 PP

>> Ribosomal_S15  Ribosomal protein S15
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.1       1.5   8.7e+02      21      41 ..     207     227 ..     201     241 .. 0.77
   2 ?    8.6   0.1    0.0037       2.2      12      49 ..     248     285 ..     237     291 .. 0.86
   3 ?   -2.4   0.0       9.5   5.7e+03      26      38 ..     432     444 ..     421     450 .. 0.77

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 1.5
                    HHHHHHHHHHHHHHHHHCTTT CS
  Ribosomal_S15  21 qiallterInnltehlkenkk 41 
                     i  l e+I++l+e l+ + +
     EEA22164.1 207 EIQALQEKIKSLEEELQARDR 227
                    577899999999999988765 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.0037
                    TT-TSSHHHHHHHHHHHHHHHHHHHHCTTT-HHHHHHH CS
  Ribosomal_S15  12 ekDtGspevqiallterInnltehlkenkkDkhsrrgL 49 
                     +D  s+  q+    e+I +lt  +++++ D++s    
     EEA22164.1 248 GQDGASIRAQLREKNEKIAQLTAEFDSHRADFRSTLDT 285
                    5788999*************************998665 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 9.5
                    HHHHHHHHHHHHC CS
  Ribosomal_S15  26 terInnltehlke 38 
                    terI +l+e +ke
     EEA22164.1 432 TERISQLEERIKE 444
                    6777777776654 PP

>> ATG16  Autophagy protein 16 (ATG16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1  16.9     0.019        11      70     184 ..     202     311 ..     160     314 .. 0.51
   2 ?    3.3  14.5      0.14        84      57     130 ..     306     379 ..     283     409 .. 0.47
   3 ?    4.3   0.2     0.071        43      98     134 ..     429     465 ..     422     472 .. 0.66

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.019
       ATG16  70 skqsakiqsleqklaqlreelaelyksrgelaqrllelneelqkleekl.kedeerlaeleaeraaletklkdreeelrekeklvqdlqDElsaLqlql 167
                  + s++iq+l++k+++l eel++  ++  + a+ l+el++++ +le +   + +++l+e ++++a+l+ + +++++ +r    +++    E +      
  EEA22164.1 202 GAGSQEIQALQEKIKSLEEELQARDRQLDDQASVLTELQQSITELEGQDgASIRAQLREKNEKIAQLTAEFDSHRADFRSTLDTLEVAATETE------ 294
                 456666666666666666666666666666666666666666666543213344444444444444444444444444444444333333322...... PP

       ATG16 168 nqaEeklrklekENkeL 184
                    E++l++l + N+eL
  EEA22164.1 295 RVYEKRLDELMQQNREL 311
                 23344444555555555 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.14
       ATG16  57 sakekeasasqsnskqsakiqsleqklaqlreelaelyksrgelaqrllelneelqkleeklkedeerlaelea 130
                 +++++++ + ++ ++ + ++++le+++++l e l+++ +  +e    +  l  e+++ + +lk+++e+ a++ +
  EEA22164.1 306 QQNRELQDRGEDVEAVALQLKQLEELVSELEEGLEDARRGEAEARGEVEFLRGEVERAQLELKQEREKSAAALK 379
                 12222222222344444555555555555555555555555555555555555555555555554444433332 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.071
       ATG16  98 gelaqrllelneelqkleeklkedeerlaeleaeraa 134
                 ++ ++r+ +l+e +++le  ++ +++r++el++e  +
  EEA22164.1 429 SHDTERISQLEERIKELEGVAEIRSSRIDELQRELGQ 465
                 4445666677777777777777777777777666554 PP

>> SlyX  SlyX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   8.1    0.0047       2.8       1      39 [.     211     249 ..     211     277 .. 0.83
   2 ?    5.7   6.0     0.037        22       4      56 ..     282     334 ..     279     350 .. 0.85
   3 ?    5.3   0.0      0.05        30      11      43 ..     434     466 ..     432     483 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0047
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        SlyX   1 leerleeLEiklafqedtieeLndvvaeqqqqidrlqrq 39 
                 l+e+++ LE++l   ++++++   v++e qq i++l+ q
  EEA22164.1 211 LQEKIKSLEEELQARDRQLDDQASVLTELQQSITELEGQ 249
                 689*********************************976 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.037
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT-XXXXXXXXX CS
        SlyX   4 rleeLEiklafqedtieeLndvvaeqqqqidrlqrqlrllaerlkeleessga 56 
                  l+ LE+  + +e++ e+  d++++q+++++   + ++++a +lk+lee  ++
  EEA22164.1 282 TLDTLEVAATETERVYEKRLDELMQQNRELQDRGEDVEAVALQLKQLEELVSE 334
                 68999**********99999999999999999999999999999999887654 PP

  == domain 3  score: 5.3 bits;  conditional E-value: 0.05
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        SlyX  11 klafqedtieeLndvvaeqqqqidrlqrqlrll 43 
                 +++ +e+ i+eL  v      +id+lqr+l + 
  EEA22164.1 434 RISQLEERIKELEGVAEIRSSRIDELQRELGQN 466
                 677788888888888888888888888888765 PP

>> DUF812  Protein of unknown function (DUF812)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8  16.9   0.00055      0.33     351     481 ..     206     337 ..     200     344 .. 0.79
   2 ?    4.1   2.7     0.028        17     327     409 ..     327     408 ..     323     416 .. 0.83
   3 ?    1.6   2.1      0.17        99     390     426 ..     434     470 ..     366     473 .. 0.71

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00055
      DUF812 351 eeikklessikqveeeleeekeeneelekevklkkktlellpdaeeniekLqalveasaqrlvelakqWekhRvplieeyrelkesksekekeaerkle 449
                 +ei++l+++ik +eeel++++++   +++ +   ++ +  l+ ++   +   a + ++++++ +l +++++hR+     + +l+ +++e+e  +e++l+
  EEA22164.1 206 QEIQALQEKIKSLEEELQARDRQLDDQASVLTELQQSITELEGQD--GASIRAQLREKNEKIAQLTAEFDSHRADFRSTLDTLEVAATETERVYEKRLD 302
                 677888888888888888888888888877777777777774443..46678999999****************************************9 PP

      DUF812 450 eikklrekmkevaeelrqkeellkqL...vaelek 481
                 e+ +  +++++  e++   + +lkqL   v+ele+
  EEA22164.1 303 ELMQQNRELQDRGEDVEAVALQLKQLeelVSELEE 337
                 99999999999988888888888887322444444 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.028
      DUF812 327 kreeeleelqeqieeleskieeleeeikklessikqveeeleeekeeneelekevklkkktlellpdaeeniekLqalveasa 409
                 + ee ++el+e +e++++  +e + e++ l+ ++++++ el++e+e+ +   k+ + +      l++ +  i+ L+a++ + +
  EEA22164.1 327 QLEELVSELEEGLEDARRGEAEARGEVEFLRGEVERAQLELKQEREKSAAALKDAEGRWNGR-ELEQKDDEIRGLKAIIHSLS 408
                 44556789************************************999999888887766654.56688888999999888765 PP

  == domain 3  score: 1.6 bits;  conditional E-value: 0.17
      DUF812 390 llpdaeeniekLqalveasaqrlvelakqWekhRvpl 426
                  + + ee i++L+ + e  ++r+ el+++  + R+pl
  EEA22164.1 434 RISQLEERIKELEGVAEIRSSRIDELQRELGQNRSPL 470
                 4556788899999999999999999999999999887 PP

>> Fez1  Fez1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   2.5      0.11        66      31      73 ..     206     248 ..     197     253 .. 0.85
   2 ?   11.7  16.9   0.00045      0.27      30     154 ..     248     377 ..     236     387 .. 0.70
   3 ?    3.1   0.4      0.19   1.2e+02      63     101 ..     430     468 ..     378     529 .. 0.60

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.11
        Fez1  31 seivalkaqlrelrakleekeeeikeleesleektlelevcen 73 
                 +ei al+ +++ l+++l+++++++++  + l+e ++++ ++e 
  EEA22164.1 206 QEIQALQEKIKSLEEELQARDRQLDDQASVLTELQQSITELEG 248
                 7899999999999999999999999999988888888877765 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 0.00045
        Fez1  30 lseivalkaqlrelrakleekeeeikeleesleektlelevcenelqrk........kseaellrekvekleeelkelreelselsleeeeaalesdea 120
                 +++  +++aqlre ++k+ +  +e +++++ +++  + lev   e +r          +++  l+++ e +e+   +l++ l+el +e ee  +++   
  EEA22164.1 248 GQDGASIRAQLREKNEKIAQLTAEFDSHRADFRSTLDTLEVAATETERVyekrldelMQQNRELQDRGEDVEAVALQLKQ-LEELVSELEEGLEDA--R 343
                 55667889999999999999999999999999999999999888888887766666655566666666666666666666.444443333332222..2 PP

        Fez1 121 kaqrqeaeeleelkreverlraeLkeerqkkeeq 154
                 + + +++ e+e l+ ever + eLk+er+k+ + 
  EEA22164.1 344 RGEAEARGEVEFLRGEVERAQLELKQEREKSAAA 377
                 34445578999*****************997654 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.19
        Fez1  63 ektlelevcenelqrkkseaellrekvekleeelkelre 101
                 + t+ + ++e+++++ +  ae+ + ++++l++el + r+
  EEA22164.1 430 HDTERISQLEERIKELEGVAEIRSSRIDELQRELGQNRS 468
                 333334444444444444444444444444444444444 PP

>> DUF5320  Family of unknown function (DUF5320)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.1    0.0013       0.8      70      98 ..     203     231 ..     187     232 .. 0.86
   2 ?   -0.9   0.0       6.1   3.6e+03      64      98 ..     424     458 ..     393     459 .. 0.69

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.0013
     DUF5320  70 skeeekelLeeqaeaLeeeleaikkrlke 98 
                 + ++e+++L+e++++Leeel+a +++l++
  EEA22164.1 203 AGSQEIQALQEKIKSLEEELQARDRQLDD 231
                 56799*******************99975 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 6.1
     DUF5320  64 aetaeaskeeekelLeeqaeaLeeeleaikkrlke 98 
                 +  +++   e+++ Lee+++ Le   e  ++r++e
  EEA22164.1 424 HGDSRSHDTERISQLEERIKELEGVAEIRSSRIDE 458
                 44556666777788888888888777777777666 PP

>> BLOC1_2  Biogenesis of lysosome-related organelles complex-1 subunit 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   3.5     0.023        14      33      78 ..     205     247 ..     202     252 .. 0.79
   2 ?    9.2   3.2    0.0025       1.5      47      86 ..     298     337 ..     289     341 .. 0.91
   3 ?    2.8   0.1      0.25   1.5e+02      65      82 ..     433     450 ..     426     465 .. 0.74

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.023
     BLOC1_2  33 sekykklkdvaaslekkleklnekyeelqpylqqidqiekqvteLe 78 
                 s+++++l+++++sle++l++ ++   +l+ + + + ++++++teLe
  EEA22164.1 205 SQEIQALQEKIKSLEEELQARDR---QLDDQASVLTELQQSITELE 247
                 56777788888888877776666...99999999999999999998 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.0025
     BLOC1_2  47 ekkleklnekyeelqpylqqidqiekqvteLeeavseLDe 86 
                 ek l++l +++ elq   + ++++  q+++Lee+vseL+e
  EEA22164.1 298 EKRLDELMQQNRELQDRGEDVEAVALQLKQLEELVSELEE 337
                 78899*********************************97 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.25
     BLOC1_2  65 qqidqiekqvteLeeavs 82 
                 ++i q+e++++eLe +++
  EEA22164.1 433 ERISQLEERIKELEGVAE 450
                 678899999999998875 PP

>> DUF16  Protein of unknown function DUF16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   4.0     0.011       6.5      55      95 ..     206     246 ..     202     250 .. 0.89
   2 ?    8.4   0.3    0.0051         3      53     102 ..     254     304 ..     245     306 .. 0.84
   3 ?    5.9   1.3     0.029        17      16      75 ..     292     351 ..     290     367 .. 0.79
   4 ?    5.0   0.4     0.058        35      41      71 ..     433     463 ..     366     472 .. 0.76

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.011
                 HHHHHHHHHHHHHHHHHHHHHH.......HHHHHHHHHHHH CS
       DUF16  55 qkvekqgekikelkveqkaqgeelnkvdetleliletLqki 95 
                 q++++++ekik l++e +a++++l+ + + l  + ++++++
  EEA22164.1 206 QEIQALQEKIKSLEEELQARDRQLDDQASVLTELQQSITEL 246
                 88999********************9999999999988876 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0051
                 HHHHHHHHHHHHHHHHHHHHHHHH.......HHHHHH.HHHHHHHHHHHHH CS
       DUF16  53 leqkvekqgekikelkveqkaqgeelnkvdetlelil.etLqkinkRlDsi 102
                 +  + ++++eki +l++e +  ++++ +  +tle+ + et    +kRlD++
  EEA22164.1 254 IRAQLREKNEKIAQLTAEFDSHRADFRSTLDTLEVAAtETERVYEKRLDEL 304
                 566788999************************997626666789****86 PP

  == domain 3  score: 5.9 bits;  conditional E-value: 0.029
                 XTTB-BHHHHHHB-..BHHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHH.HHHHHH CS
       DUF16  16 kteYVTrkqlnefkdsnkqrLkkieakvdklgeqinkleqkvekqgekikelkv.eqkaqg 75 
                 +te V  k l+e  ++ + +L++  + v++   q+++le+ v++++e +++ +  e +a+g
  EEA22164.1 292 ETERVYEKRLDELMQQ-NRELQDRGEDVEAVALQLKQLEELVSELEEGLEDARRgEAEARG 351
                 6788999999999966.578999999****************9999988765431445544 PP

  == domain 4  score: 5.0 bits;  conditional E-value: 0.058
                 HHHH...HHHHHHHHHHHHHHHHHHHHHHHH CS
       DUF16  41 akvdklgeqinkleqkvekqgekikelkveq 71 
                 +++++l+e+i++le   e    +i+el+ e 
  EEA22164.1 433 ERISQLEERIKELEGVAEIRSSRIDELQREL 463
                 4566677777777777777777777777665 PP

>> Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   3.1    0.0054       3.3      39      99 ..     207     270 ..     202     272 .. 0.70
   2 ?    4.6   1.5      0.05        30      23      97 ..     256     335 ..     249     343 .. 0.82
   3 ?   -1.7   0.0       4.7   2.8e+03      48      97 ..     354     407 ..     347     410 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0054
  Baculo_PEP_C  39 lldaietqLnalsedlksllaeldtrldtlltnLtdalnalq....dtlrneLtnlnsiltnLls 99 
                    ++a+++++++l+e+l++   +ld++ +++lt+L++++ +l+     ++r +L   n ++++L++
    EEA22164.1 207 EIQALQEKIKSLEEELQARDRQLDDQ-ASVLTELQQSITELEgqdgASIRAQLREKNEKIAQLTA 270
                   45555566666666665544444433.55677888888888899888999***999999999997 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.05
  Baculo_PEP_C  23 nairlqnvqilaqlatlldaietqLnalsedlksllaeldtrldtlltnLtdalnalq......dtlrneLtnlnsiltnL 97 
                   +++r +n +i aql++ +d+    + +  + l+ + +e ++  ++ l++L ++  +lq      +++  +L+ l+  +++L
    EEA22164.1 256 AQLREKNEKI-AQLTAEFDSHRADFRSTLDTLEVAATETERVYEKRLDELMQQNRELQdrgedvEAVALQLKQLEELVSEL 335
                   4678889999.9999999999999999999999999999999999999999999999977776667777777777777666 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 4.7
  Baculo_PEP_C  48 nalsedlksllaeldtrldtlltnLtdalnalq....dtlrneLtnlnsiltnL 97 
                   + l  +++++  el+++ ++++++L+da  + +    ++ + e+ +l++i+ +L
    EEA22164.1 354 EFLRGEVERAQLELKQEREKSAAALKDAEGRWNgrelEQKDDEIRGLKAIIHSL 407
                   557778999999999999999999999999999988888888999999888877 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   9.8    0.0018       1.1     156     239 ..     206     289 ..     202     296 .. 0.86
   2 ?    8.6  11.6    0.0013      0.77     159     279 ..     284     401 ..     277     417 .. 0.73

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0018
        Spc7 156 elLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieel 239
                 +++++ +e++++l +el+++  +l +++  l e ++++++++ ++ +++r +l+e +++i+++ +e ++ +++  +  +++e +
  EEA22164.1 206 QEIQALQEKIKSLEEELQARDRQLDDQASVLTELQQSITELEGQDGASIRAQLREKNEKIAQLTAEFDSHRADFRSTLDTLEVA 289
                 67899999*************************99999**9999999**************99999988888777766666554 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.0013
        Spc7 159 ekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaervl 257
                 +  e  ++e    +e++ +el+++ ++lq++ e++e++   +L++l e ++el++ +e  ++  ae + ++e l+ ++e ++ + ++ +e+ a    ++
  EEA22164.1 284 DTLEVAATETERVYEKRLDELMQQNRELQDRGEDVEAVA-LQLKQLEELVSELEEGLEDARRGEAEARGEVEFLRGEVERAQLELKQEREKSA--AALK 379
                 555566677777888888899999999999888888864.57888888888888888888889999999999999888888766666555544..4444 PP

        Spc7 258 eeckgwsesevsrlkeevkale 279
                 +++ +w+  e+++  +e + l+
  EEA22164.1 380 DAEGRWNGRELEQKDDEIRGLK 401
                 5556677666666666665554 PP

>> DUF3584  Protein of unknown function (DUF3584)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1  25.6    0.0055       3.3     248     456 ..     206     413 ..     202     472 .. 0.63

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.0055
     DUF3584 248 eklqeefeqleslelrLsllkgelkadeerlaekqeevqeakaelkqqlrtledelkeaidelnqelsaakaklaakeselealeeqkkkyedadiekl 346
                 +++q+  e+++sle++L+   ++l ++ + l+e q+ + e + +  +++r++  e +e+i++l+ e    +a+     + le +  + ++  ++++++l
  EEA22164.1 206 QEIQALQEKIKSLEEELQARDRQLDDQASVLTELQQSITELEGQDGASIRAQLREKNEKIAQLTAEFDSHRADFRSTLDTLEVAATETERVYEKRLDEL 304
                 456667777778888888888888888888888888888888887788777777778888888888888888888888888877777777777777777 PP

     DUF3584 347 kadldqlpsirseleeleeeldaltekhqdvqekydrrkqkikeeleeeleklkerleaireekdrlkaaieealealesqlrkqleaqkeelneeeke 445
                  ++  +l    +++e++  +l+ l+e + +++e ++  +   + e   e+e l+ ++e  + e ++ +++  +al+  e  ++ ++ +qk +  +  k 
  EEA22164.1 305 MQQNRELQDRGEDVEAVALQLKQLEELVSELEEGLEDARR-GEAEARGEVEFLRGEVERAQLELKQEREKSAAALKDAEGRWNGRELEQKDDEIRGLKA 402
                 7777777777788888888888888888888777764433.2334444555555554433333344466666777777777777777776666666666 PP

     DUF3584 446 lesrlselklr 456
                 + ++ls+ ++ 
  EEA22164.1 403 IIHSLSRGEVN 413
                 76666666554 PP

>> C1_2  C1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   0.2     0.046        28      13      35 ..     581     602 ..     564     606 .. 0.78
   2 ?    3.9   0.3      0.11        67      16      29 ..     701     714 ..     696     720 .. 0.84

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.046
        C1_2  13 edssesfnCsaCgrkidgffYsC 35 
                 +++ +s +C++C++++++   +C
  EEA22164.1 581 SSEGGSLWCEICETNGHD-ILTC 602
                 5667889******99633.3555 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.11
        C1_2  16 sesfnCsaCgrkid 29 
                 +es++C +C+r+++
  EEA22164.1 701 DESKWCALCERDGH 714
                 689********975 PP

>> EzrA  Septation ring formation regulator, EzrA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   7.6    0.0015      0.87      93     187 ..     212     308 ..     206     314 .. 0.88
   2 ?    7.5   1.1    0.0017      0.99     379     432 ..     316     369 ..     313     371 .. 0.92
   3 ?   -1.4   0.2      0.84     5e+02     115     143 ..     433     461 ..     428     469 .. 0.57

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0015
                 SHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHTHHHHTTTTT.HHHHHHHHHHHHHHHHT--TTTTHHHHHHHHHHHHHHHH------.-------- CS
        EzrA  93 kykfkkakkklaeleeeldeveekikkileelkelteseekn.reeieklkekYrelrkkllanrfsygealeelekqleniekefse.feelteng 187
                 + k+k+++++l++ + +ld+  + + ++++ ++el  ++  + r++  + +ek  +l  ++ ++r+++ ++l++le    + e+ +++ ++el++++
  EEA22164.1 212 QEKIKSLEEELQARDRQLDDQASVLTELQQSITELEGQDGASiRAQLREKNEKIAQLTAEFDSHRADFRSTLDTLEVAATETERVYEKrLDELMQQN 308
                 5689999999**************************99965449********************************999999998865377777776 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0017
                 GGTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSS CS
        EzrA 379 eeleeleekleeieekqeeileslkslrkdEkrAreqldeikkelkeikrkiek 432
                 e++e +  +l+++ee + e++e l++ r+ E++Ar +++ ++ e++ ++ ++++
  EEA22164.1 316 EDVEAVALQLKQLEELVSELEEGLEDARRGEAEARGEVEFLRGEVERAQLELKQ 369
                 67899999*********************************9999999988887 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.84
                 HHHHHHHHHHTHHHHTTTTTHHHHHHHHH CS
        EzrA 115 ekikkileelkelteseeknreeieklke 143
                 e+i ++ e +kel    e  +++i++l+ 
  EEA22164.1 433 ERISQLEERIKELEGVAEIRSSRIDELQR 461
                 44555555555555555555555555543 PP

>> Peptidase_S46  Peptidase S46
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1  11.7    0.0061       3.6     272     444 ..     206     382 ..     202     404 .. 0.72

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0061
                    HHHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHCT-H.HHHTTHHHHHHHHHHHHHHHH CS
  Peptidase_S46 272 arievleeriallkeemkkdpeirikyasklagleNylKnliGmlealkkkkvlekkqaeeaalrawlkkdpekkekygkalselealvkekrkla 367
                    + i+ l+e+i+ l+ee ++++ +   +as l +l+ ++ +l+G+  a  + + l++k+++ a+l+a  +++ +   ++  +l++le + +e+++++
     EEA22164.1 206 QEIQALQEKIKSLEEELQARDRQLDDQASVLTELQQSITELEGQDGASIRAQ-LREKNEKIAQLTAEFDSHRA---DFRSTLDTLEVAATETERVY 297
                    568999*************************************977666555.56778888888888888887...56666777776666666555 PP

                    HH.....HHHHHHHTTTTSHHHHHHHHHHHHHHHHH.........HH-HHHHHHHHHHHHHHCHHHHCS--HHHHHHHHHHHHHHHH CS
  Peptidase_S46 368 er.....salleeaessgsellslarklvrlaeere.....kpdaereeeyqeralealekeleridkdldaevdkavlaallkeyr 444
                    e+     ++  +e++ +g ++  +a +l++l+e  +      +da r e   + ++e l+ e+er   +l+ + +++  aa lk++ 
     EEA22164.1 298 EKrldelMQQNRELQDRGEDVEAVALQLKQLEELVSeleegLEDARRGEAEARGEVEFLRGEVERA--QLELKQEREKSAAALKDAE 382
                    441111123344556677778888887777765333222336789999999999999999999998..5555555666666666655 PP

>> SKA1  Spindle and kinetochore-associated protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   3.6    0.0048       2.9      22      69 ..     205     252 ..     192     295 .. 0.78
   2 ?    3.3   1.3       0.1        63      45     102 ..     303     360 ..     267     395 .. 0.54

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0048
                 ..XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..... CS
        SKA1  22 kedlskieaevsaleellnklkkelqeeeeaikklkkeieaslkqqek 69 
                 ++ ++++++++++lee l++  ++l+++++++ +l++ i +   q+  
  EEA22164.1 205 SQEIQALQEKIKSLEEELQARDRQLDDQASVLTELQQSITELEGQDGA 252
                 678999999999999999999999999999999999999887766654 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.1
                 XXXXXXXXXXXXXXXXXXXX.....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        SKA1  45 elqeeeeaikklkkeieaslkqqeklqhlkenlpshlpkktaassaeeskssspeeee 102
                 el +++  +++  +++ea + q ++l+ l ++l ++l++ ++ + + + + +   +e+
  EEA22164.1 303 ELMQQNRELQDRGEDVEAVALQLKQLEELVSELEEGLEDARRGEAEARGEVEFLRGEV 360
                 3333333333333355555544444555555555555544444444444444333333 PP

>> TolA_bind_tri  TolA binding protein trimerisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   8.3     0.012       7.1       2      40 ..     211     249 ..     210     282 .. 0.77
   2 ?    8.4   3.7    0.0038       2.3       5      67 ..     324     386 ..     320     394 .. 0.85
   3 ?    7.4   0.4    0.0078       4.7       1      32 [.     437     468 ..     437     472 .. 0.92

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.012
  TolA_bind_tri   2 ledrvarLErilearsqlllelqqqlealqqelreLRGq 40 
                    l++++++LE+ l+ar++ l ++ + l +lqq + eL Gq
     EEA22164.1 211 LQEKIKSLEEELQARDRQLDDQASVLTELQQSITELEGQ 249
                    788999999999999977777777777777777777776 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0038
  TolA_bind_tri   5 rvarLErilearsqlllelqqqlealqqelreLRGqiEelqyqleqleerQrdlYldlDerlr 67 
                    ++++LE++++  +++l +  +   + + e+  LRG++E+ q +l+q +e+     +d + r +
     EEA22164.1 324 QLKQLEELVSELEEGLEDARRGEAEARGEVEFLRGEVERAQLELKQEREKSAAALKDAEGRWN 386
                    5788888888888888888888899999******************99999988888888766 PP

  == domain 3  score: 7.4 bits;  conditional E-value: 0.0078
  TolA_bind_tri   1 sledrvarLErilearsqlllelqqqlealqq 32 
                    +le+r+++LE  +e rs+ + elq++l ++++
     EEA22164.1 437 QLEERIKELEGVAEIRSSRIDELQRELGQNRS 468
                    79*************************99875 PP

>> TMF_DNA_bd  TATA element modulatory factor 1 DNA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   2.4   0.00049      0.29      32      73 ..     205     246 ..     201     248 .. 0.73
   2 ?    8.3   4.4    0.0037       2.2       2      67 ..     253     312 ..     252     317 .. 0.66
   3 ?    0.5   4.9         1   6.2e+02      27      72 ..     293     341 ..     288     343 .. 0.80
   4 ?   -1.3   0.1       3.8   2.3e+03       6      18 ..     389     401 ..     386     409 .. 0.84
   5 ?    2.6   0.1      0.22   1.3e+02      32      65 ..     432     465 ..     419     472 .. 0.64

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00049
  TMF_DNA_bd  32 nntikkLrkknkelekeikelkkkleklekeleeleerlkea 73 
                 ++ i  L++k+k le+e++  +++l+++ + l+el+++ +e 
  EEA22164.1 205 SQEIQALQEKIKSLEEELQARDRQLDDQASVLTELQQSITEL 246
                 567777888888888888888888888888888887776655 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.0037
  TMF_DNA_bd   2 slekklkeKDeqIaqLmeEGekLskkelklnntikkLrkknkelekeikelkkkleklekeleele 67 
                 s++++l+eK+e+IaqL +E     +   + + t++ L   + e+e   + ++k+l++l ++  el+
  EEA22164.1 253 SIRAQLREKNEKIAQLTAE---FDSHRADFRSTLDTLEVAATETE---RVYEKRLDELMQQNRELQ 312
                 67899************76...45555666666666666666655...345555555555555555 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 1
  TMF_DNA_bd  27 kelklnntikkLrkknkele...keikelkkkleklekeleeleerlke 72 
                 +e+  ++ +++L ++n+el    ++++    +l++le+ ++elee l+ 
  EEA22164.1 293 TERVYEKRLDELMQQNRELQdrgEDVEAVALQLKQLEELVSELEEGLED 341
                 5666778899999999999977788888889999999999999987765 PP

  == domain 4  score: -1.3 bits;  conditional E-value: 3.8
  TMF_DNA_bd   6 klkeKDeqIaqLm 18 
                  l++KD++I  L+
  EEA22164.1 389 ELEQKDDEIRGLK 401
                 5899999999886 PP

  == domain 5  score: 2.6 bits;  conditional E-value: 0.22
  TMF_DNA_bd  32 nntikkLrkknkelekeikelkkkleklekelee 65 
                  + i++L + +kele   +  ++++++l++el +
  EEA22164.1 432 TERISQLEERIKELEGVAEIRSSRIDELQRELGQ 465
                 5566666666666665555555666666666654 PP

>> DUF4407  Domain of unknown function (DUF4407)
   [No individual domains that satisfy reporting thresholds (although complete target did)]

>> DUF724  Protein of unknown function (DUF724)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   4.7    0.0011      0.68     104     176 ..     208     281 ..     205     293 .. 0.78
   2 ?    0.9   9.4      0.58   3.5e+02      67     166 ..     298     403 ..     287     448 .. 0.72
   3 ?   -1.2   0.1       2.5   1.5e+03     124     147 ..     427     450 ..     411     468 .. 0.60

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0011
      DUF724 104 qtklleerkklekkieeeesekrkleeeidelekkilelerql.allkekkeaadkeiarlkseaekleeeled 176
                  + l+e++k le++++  + +     + + el++ i ele q+ a+++++  +++++ia+l +e ++ + + ++
  EEA22164.1 208 IQALQEKIKSLEEELQARDRQLDDQASVLTELQQSITELEGQDgASIRAQLREKNEKIAQLTAEFDSHRADFRS 281
                 567899999999999999999999999999**********9983457788888888888888877666655554 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.58
      DUF724  67 rseleslkeslaeLekhGFdVkalqsrlnkLlslkdeqtklleerkklekkieeeesekrkleeeidelekkilelerqlallk............ekk 153
                 ++ l++l+++  eL+  G dV+a+  +l++L +l +e ++ le  ++ e + + e +          e+e++ lel+++++               ++ 
  EEA22164.1 298 EKRLDELMQQNRELQDRGEDVEAVALQLKQLEELVSELEEGLEDARRGEAEARGEVEFL------RGEVERAQLELKQEREKSAaalkdaegrwngREL 390
                 56788889999999999999999998888888888887777777777666555444433......3344444444433333222233366666777777 PP

      DUF724 154 eaadkeiarlkse 166
                 e++d ei  lk+ 
  EEA22164.1 391 EQKDDEIRGLKAI 403
                 7778888777765 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 2.5
      DUF724 124 ekrkleeeidelekkilelerqla 147
                 ++++  e i++le++i+ele  ++
  EEA22164.1 427 SRSHDTERISQLEERIKELEGVAE 450
                 444445666666666666665444 PP

>> Phage_GP20  Phage minor structural protein GP20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   7.0     0.011       6.4      18      79 ..     206     268 ..     198     286 .. 0.79
   2 ?    6.4   5.3     0.012       7.3       9     136 ..     290     418 ..     284     431 .. 0.69
   3 ?   -2.6   0.0         7   4.2e+03       9      42 ..     593     627 ..     590     631 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.011
  Phage_GP20  18 akldeveeerdtlkeqlkdrdkqLedLkkkakdneeLqkqieelqak....nkkakaeyeakiadl 79 
                 ++++ ++e  ++l+e+l++rd qL+d   +    +eLq+ i+el+ +    + ++  e ++kia+l
  EEA22164.1 206 QEIQALQEKIKSLEEELQARDRQLDDQASV---LTELQQSITELEGQdgasIRAQLREKNEKIAQL 268
                 778899999****************98666...9**********9641111445555555666655 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.012
  Phage_GP20   9 aengkditkakldeveeerdtlkeqlkdrdkqLedLkkkakdneeLqkqieelqaknkkakaeyeakiadlkld.naielaLkeakaknekavkal... 103
                 a +++ + +++lde+ +++ +l+    dr +++e    + k  eeL  ++ee  +++ + +ae+  +++ l  + +  +l+Lk+ + k+++a+k     
  EEA22164.1 290 ATETERVYEKRLDELMQQNRELQ----DRGEDVEAVALQLKQLEELVSELEEGLEDARRGEAEARGEVEFLRGEvERAQLELKQEREKSAAALKDAegr 384
                 55666677777777777766555....555555555555555567777777777777777777888887776541456899999999999999865222 PP

  Phage_GP20 104 ldkdklklkedgelkgLdeqikkLkesd..kyLFe 136
                  +  +l+ k+d e+ gL+  i +L+ ++    +F+
  EEA22164.1 385 WNGRELEQKDD-EIRGLKAIIHSLSRGEvnPAMFN 418
                 56889999666.8***********98776666775 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 7
  Phage_GP20   9 aengkdi.tkakldeveeerdtlkeqlkdrdkqLe 42 
                 + ng+di t + + + ++  d++++q + +d++ +
  EEA22164.1 593 ETNGHDIlTCTTFGTNTSGTDSMNQQYEHNDNEFK 627
                 66777775588888888899999999999988766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (723 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1406  (0.0784204); expected 358.6 (0.02)
Passed bias filter:                      694  (0.0387082); expected 358.6 (0.02)
Passed Vit filter:                       150  (0.00836633); expected 17.9 (0.001)
Passed Fwd filter:                        92  (0.00513135); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              30  [number of targets reported over threshold]
# CPU time: 1.38u 0.39s 00:00:01.77 Elapsed: 00:00:00.58
# Mc/sec: 3775.47
//
Query:       EEA22165.1  [L=422]
Description: serine/threonine protein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    5.8e-38  130.8   0.0    3.3e-21   75.9   0.0    2.1  2  Pkinase      Protein kinase domain
    3.4e-14   52.7   0.0    1.6e-06   27.7   0.0    2.9  2  Pkinase_Tyr  Protein tyrosine kinase
     0.0011   18.3   0.0       0.43    9.9   0.0    2.4  2  Kinase-like  Kinase-like
  ------ inclusion threshold ------
      0.021   14.8   0.1      0.034   14.1   0.1    1.6  1  APH          Phosphotransferase enzyme family


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.9   0.0   7.2e-18   3.2e-14       2     119 ..      33     168 ..      32     169 .. 0.94
   2 !   75.9   0.0   7.3e-25   3.3e-21     120     260 ..     237     408 ..     234     410 .. 0.80

  Alignments for each domain:
  == domain 1  score: 52.9 bits;  conditional E-value: 7.2e-18
                 EEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHS.CTTB--EEEEEEE..............SSEEEEEEE--TTEBH CS
     Pkinase   2 ekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklk.hpnivrlyevfee..............kdelylvleyveggel 85 
                 + l+ lGeG+f+ Vy + +k+t++ +A+Kki+    +++  +++l+E++    +   p+i++ y+ +                ++++y++l y + g+l
  EEA22165.1  33 KLLRLLGEGGFSYVYLVQDKSTSELFALKKIRCPFGQESV-SQALKEVEAYSLFTpNPYIIQSYDHCVVnesankfrggddssSKTVYILLPYYQRGNL 130
                 67899****************************9988877.59**********************8877789***********9*************** PP

                 HHHHH....HHSS--HHHHHHHHHHHHHHHHHHHHTTE CS
     Pkinase  86 adlle....rkgslseeeakkiakqilegleylHskgi 119
                 +d+++    +++s++e+e+  ++  ++++l+ +H+ ++
  EEA22165.1 131 QDAINanlvNHTSFPEKELMTLMLGVAKALKAMHQYRV 168
                 *****9999999**********************9876 PP

  == domain 2  score: 75.9 bits;  conditional E-value: 7.3e-25
                 E-SS-SGGGEEEETTTE.EEE-SGTTSEESSSSCS..........BCTTTSCGGGS-HHHH...TTSCBSHHHHHHHHHHHHHHHHHSS-STTTSSHHH CS
     Pkinase 120 iHrDlKpeNiLidekge.lKitDFGlakelesssk..........ltsfvgtseYlAPEvl...keneyskkvDvWslGvilyelltgkppfsgekgke 204
                  HrD+Kp Ni+id++g    ++D+G  +      +          +  +  t  Y+APE+    +++ +++kvD+WslG++ly  l gk pf+++++++
  EEA22165.1 237 AHRDIKPGNIMIDDDGRtPILMDLGSLAPSPIAITsrslalavqdTAAEHSTMPYRAPELFdvkTGSIIDTKVDIWSLGCTLYACLVGKSPFEARSEET 335
                 6************888878899***7554333333346799999999999**********998445556************************555444 PP

                 HHHHHHHTHHHHHHHCT.SHH...HHHTTS.......................-HHHHHHHHHHT-SSGCCSTTHHHHHT CS
     Pkinase 205 kvekeldqlekilkilg.etkeklpeasei.......................seeakdllkkllkkdpkkRltaeellq 260
                            ++ +lg ++++  ++as+                        se++kd+++k+l+++p +R+ ++el+q
  EEA22165.1 336 ------GGSL-SMCVLGgDWRFPDENASSAkgkaksntpaasgssqssgeggiSESVKDIVRKCLQVEPAERPDIDELIQ 408
                 ......3322.3344554666666666666777788999999********************************999876 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.7   0.0   4.7e-08   0.00021       2     121 ..      33     165 ..      32     169 .. 0.88
   2 !   27.7   0.0   3.5e-10   1.6e-06     122     257 ..     234     408 ..     225     410 .. 0.76

  Alignments for each domain:
  == domain 1  score: 20.7 bits;  conditional E-value: 4.7e-08
                  EEEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS.-BTTB--EEEEEE..SSSS..............EEEEEE- CS
  Pkinase_Tyr   2 elgkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkkl.khpnivkllgvct..keep..............llivtey 82 
                  +l + lGeG f+ V+  + k    ++++  a+K+++    +e+ ++ l+e++  + +  +p i++ +  c+  +  +              ++i++ y
   EEA22165.1  33 KLLRLLGEGGFSYVYLVQDK----STSELFALKKIRCPFGQESVSQALKEVEAYSLFtPNPYIIQSYDHCVvnE--SankfrggddsssktVYILLPY 124
                  67789**********98877....88999****************************9************9651..334566677777778******* PP

                  -TTEBHHHHHHHT..CTTTSBHHHHHHHHHHHHHHHHHHHH CS
  Pkinase_Tyr  83 vkgGdLlkfLrkk..ekekltlkdllsfalqvAkGmeyLes 121
                   + G+L++ ++++  +++++  k+l+ ++l vAk+++ +++
   EEA22165.1 125 YQRGNLQDAINANlvNHTSFPEKELMTLMLGVAKALKAMHQ 165
                  ************98888899999************998876 PP

  == domain 2  score: 27.7 bits;  conditional E-value: 3.5e-10
                  TTEEEST-SGGGEEEEETT.EEEE-STT.THEE...TTTSSEE...EETTSSTSGGGGS-HHHHHHSE...EEHHHHHHHHHHHHHHHHTTSSGT... CS
  Pkinase_Tyr 122 kklvHrdlaarNvLlsenk.vvkisDfG.Lard...iekddey...vkkeeaklpvkWmapEslkekk...ftsksDvWsfGvllwEiftlgesp... 205
                  + + Hrd+   N++++++  +  + D G La +   i++++     +++  ++  + + apE ++ k+   + +k D+Ws G +l+  +  g+sp   
   EEA22165.1 234 RPYAHRDIKPGNIMIDDDGrTPILMDLGsLAPSpiaITSRSLAlavQDTAAEHSTMPYRAPELFDVKTgsiIDTKVDIWSLGCTLYACLV-GKSPfea 330
                  5688************9551334466664332211122233223435556667889999****998887789**************9887.******* PP

                  ..........................TTTSHHHHHHHHHHTTEES-BBTTSBHHHHHHHHHHT-SSGGGS--HHHHHH CS
  Pkinase_Tyr 206 ..........................ypglkneevleklkegkrlekpekcpeelyelmkkcweedpeeRptfselve 257
                                             ++ k+++ + + + + + +    ++e+++++++kc++ +p+eRp++ el++
   EEA22165.1 331 rseetggslsmcvlggdwrfpdenasSAKGKAKSNTPAASGSSQSSGEGGISESVKDIVRKCLQVEPAERPDIDELIQ 408
                  ******************9887776433334444455556667777888899**********************9987 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.9   0.0   9.5e-05      0.43      10      48 ..      28      66 ..      22      88 .. 0.80
   2 !    6.3   0.0    0.0011       5.1     225     264 ..     303     340 ..     236     400 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 9.5e-05
  Kinase-like 10 rertlvrgellkkgdrsvvfevkdqetgeplavkvfllp 48
                  +r ++   ll++g++s v++v+d+ t e +a+k    p
   EEA22165.1 28 NNRSFKLLRLLGEGGFSYVYLVQDKSTSELFALKKIRCP 66
                 67999999*************************987655 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0011
  Kinase-like 225 tkmthkldaWqlGlviyriwclklPltlateeakeewkfk 264
                    +  k+d W lG + y     k P++   ee + +  ++
   EEA22165.1 303 SIIDTKVDIWSLGCTLYACLVGKSPFEARSEETGGS--LS 340
                  5566799*********************99999887..44 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.1   7.6e-06     0.034     164     201 ..     232     268 ..      41     270 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 7.6e-06
                 S-EEEE-SS-SGGGEEEC...TTEEEEE---TT-EEEEC CS
         APH 164 lptvllHgDlhpgNllvd.pddgrvtGviDfedaglgpp 201
                 + +   H+D++pgN+++d ++ +++  + D++ + ++p+
  EEA22165.1 232 EFRPYAHRDIKPGNIMIDdDGRTPI--LMDLGSLAPSPI 268
                 445567************6666666..888887777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (422 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       546  (0.0304535); expected 358.6 (0.02)
Passed bias filter:                      488  (0.0272185); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.49
# Mc/sec: 2600.15
//
Query:       EEA22166.1  [L=426]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.9e-13   49.2   0.1    1.5e-12   47.9   0.1    1.6  2  SpoIIE    Stage II sporulation protein E (SpoIIE)
    4.1e-11   42.9   0.6      7e-11   42.2   0.6    1.4  1  PP2C_2    Protein phosphatase 2C
    5.4e-08   32.8   0.1     0.0079   15.8   0.0    2.3  2  PP2C      Protein phosphatase 2C
  ------ inclusion threshold ------
        9.2    6.7  17.8       0.27   11.5   1.8    2.9  2  DUF3446   Early growth response N-terminal domain


Domain annotation for each model (and alignments):
>> SpoIIE  Stage II sporulation protein E (SpoIIE)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.9   0.1   3.3e-16   1.5e-12       3     144 ..     131     304 ..     129     338 .. 0.81
   2 ?   -2.7   0.0         1   4.6e+03     176     190 ..     407     421 ..     395     422 .. 0.79

  Alignments for each domain:
  == domain 1  score: 47.9 bits;  conditional E-value: 3.3e-16
                 TEEEEEEEECSS.........SSHHHHHHHHHHHHHHHHHH.HTTTSHHHHHHHHHHHCHCTTSTT.TTCEEEEEEEETTTTEEEEEEESSSSEEEEET CS
      SpoIIE   3 grlalvvgDvvG.........hGleAalimgllrsalrela.taglepaevlkrlnralardleeeerfaTavlavydpstgkleyanaGhpppllvrp 91 
                 g +a++v+D+vG          +++  l++ +++ al e a +++l+p+e+l++ ++ + +d   ++ ++Ta ++v  + +g++e+an+G++  +l+r 
  EEA22166.1 131 GAIAFAVADGVGgwaehkidpADVSHGLCTYMAQHALTEEAsQRKLRPKELLQKGYDSVVADESITAGGTTASVGV-ALTSGTVELANLGDSGSVLFRL 228
                 7899************7666666666777777777776666677777******998888555555579*******9.9********************* PP

                 TS...TEEEEE--SS--..TTTSSS..................T-EEEEEEE--TTEEEEEESCCCCSSSHHHHHH CS
      SpoIIE  92 dg...gtklllastglp..lGilpe..................adyetaelelepgdtlllyTDGvtEardsdgel 144
                          ++++++ p  l i+p                   +d+ + +l ++ gd+l+l+TDGv+++ + ++ l
  EEA22166.1 229 GAvhqYSAPQTHAFNTPyqLNIIPRrmreqahmfggvyfedspRDAAVSTLSMQHGDVLVLATDGVFDNLNNQDIL 304
                 4455555566677777799999999********************************************9665544 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 1
                 HTTSSSSS-EEEEEE CS
      SpoIIE 176 lgsgeleDDitllvl 190
                  ++g++ DDi+ lv+
  EEA22166.1 407 WYRGGKVDDICALVI 421
                 5678999****9997 PP

>> PP2C_2  Protein phosphatase 2C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.2   0.6   1.6e-14     7e-11       2     187 ..     106     305 ..     105     333 .. 0.79

  Alignments for each domain:
  == domain 1  score: 42.2 bits;  conditional E-value: 1.6e-14
      PP2C_2   2 GrshrrrglpcqDala...vwtdsggsll.aVaDGaGSakrSerGariaveavvealaelleseeeeeeallr.aleaailadvlkeeaeaqdaelkdy 95 
                 Grs+++r +  +Da++   v   + g+++ aVaDG+G  +  ++  + + + +++++a+++ +ee+++++l+  +l+++ +++v        d+++ + 
  EEA22166.1 106 GRSRQKRPASGEDAFFasrVGAVDTGAIAfAVADGVGGWAEHKIDPADVSHGLCTYMAQHALTEEASQRKLRPkELLQKGYDSV------VADESITAG 198
                 99**************98888889999999********7777777777888889999999988888888887658887777443......5799***** PP

      PP2C_2  96 atTllaav.vtpdeivalqiGDGaivvrdrdgevqllgepdsgeyanq..ttfltsedaeeel..............rirrlkledgdalllmTDGlan 177
                 +tT  ++v +t ++++++++GD++ v   r g+v++ + p+++ +      + ++++  e+                 + +l+++ gd l+l+TDG+ +
  EEA22166.1 199 GTTASVGVaLTSGTVELANLGDSGSV-LFRLGAVHQYSAPQTHAFNTPyqLNIIPRRMREQAHmfggvyfedsprdaAVSTLSMQHGDVLVLATDGVFD 296
                 ********8999************95.589*********99966654322555555433332246666666666666********************** PP

      PP2C_2 178 slrdeerfae 187
                 +l +++ + +
  EEA22166.1 297 NLNNQDIL-K 305
                 **755533.3 PP

>> PP2C  Protein phosphatase 2C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   1.8e-06    0.0079      37     137 ..     135     235 ..     109     243 .. 0.66
   2 !   14.6   0.0   4.2e-06     0.019     201     236 ..     279     315 ..     270     327 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 1.8e-06
                 EEEEEEESSSHHHHHHHHHHH.........HHHHHHHHCHTTHHHHHHHHHHHHH.HHHHHHHHHHHHCHCCT-EEEEEEEEEETTE.EEEEEESS-EE CS
        PP2C  37 favfdghggseaakyarehle.........eilksqksfeelekleqalrksfla.dtdeelksskantepsksGstavvalirgtk.lyvAnvGDSra 124
                 fav dg+gg   +k++  ++            l +  s ++l  +++ l+k++ +  +de+             G+ta+v +   +    +An+GDS  
  EEA22166.1 135 FAVADGVGGWAEHKIDPADVShglctymaqHALTEEASQRKL-RPKELLQKGYDSvVADES---------ITAGGTTASVGVALTSGtVELANLGDSGS 223
                 666666666666666666666555433322222333333333.344555555555333333.........4569****9977766666*********** PP

                 EEEETTEEEEECS CS
        PP2C 125 vLcrkgnakkelt 137
                 vL+r g  + + +
  EEA22166.1 224 VLFRLGAVH-QYS 235
                 ****99887.655 PP

  == domain 2  score: 14.6 bits;  conditional E-value: 4.2e-06
                 E-TT.EEEEEEE-HHHHTTSHHHHHHHHHHHHHHHHT CS
        PP2C 201 ltee.defliLacdGlwdvlsdqeavdlvrdelekkk 236
                 l+ +  + l+La+dG++d l++q++  +v+ ++ +++
  EEA22166.1 279 LSMQhGDVLVLATDGVFDNLNNQDILKIVTGRMLATG 315
                 55555689*********************98887655 PP

>> DUF3446  Early growth response N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   1.8   6.1e-05      0.27      41      77 ..      47      91 ..      17      97 .. 0.64
   2 ?   -0.7   8.4      0.41   1.8e+03      35      51 ..     344     360 ..     291     378 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 6.1e-05
     DUF3446 41 ssssssssssssspsl........scsvaaqqsselehiYsaaPt 77
                s + ssssss ssps         scs++    +  +h Y   Pt
  EEA22166.1 47 SRKFSSSSSSQSSPSSrisyrvagSCSAKGRRFNPEKHTYNFEPT 91
                333444444444444444566788****98888888999998887 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.41
     DUF3446  35 sspssssssssssssss 51 
                 ++pss+sss+ss+s  +
  EEA22166.1 344 QTPSSPSSSPSSTSIPP 360
                 34555666665544333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (426 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       624  (0.0348039); expected 358.6 (0.02)
Passed bias filter:                      447  (0.0249317); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 2753.28
//
Query:       EEA22167.1  [L=291]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
      0.036   13.7   1.8      0.071   12.7   1.6    1.8  2  Abhydrolase_1  alpha/beta hydrolase fold
      0.052   13.7   0.0       0.61   10.3   0.1    2.3  2  DUF5639        Family of unknown function (DUF5639)
       0.11   12.0   0.0       0.18   11.3   0.0    1.5  1  Peptidase_S9   Prolyl oligopeptidase family
       0.21   10.9   0.0       0.31   10.3   0.0    1.3  1  Hydrolase_4    Serine aminopeptidase, S33
       0.26   10.1   0.0       0.32    9.7   0.0    1.1  1  DUF1100        Alpha/beta hydrolase of unknown function (DUF1


Domain annotation for each model (and alignments):
>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   1.6     2e-05     0.071      75     126 ..     137     182 ..      20     196 .. 0.82
   2 ?   -1.8   0.0      0.56     2e+03     206     222 ..     190     213 ..     169     224 .. 0.63

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2e-05
                    EEEEEETHHHHHHHHHHHHHGGGEEEEEEESECSSCCHHHHHHHHHHHHHHC CS
  Abhydrolase_1  75 ltlvGhSmGGmialayaaeyperVkalvllgaidpaaslieaqrqqaksfpd 126
                    + l G+S GG+++  +a ++p rV+al++ ++        ++ ++  ++fpd
     EEA22167.1 137 FCLYGYSGGGQFVHRFAYLHPRRVRALACGAP------GTQTFLNFSQRFPD 182
                    3489***********************99888......55555555555554 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.56
                    C...THHHHS....EEEEEEETTC CS
  Abhydrolase_1 206 e...lknvla....ptlvisgtsD 222
                        + +++a    p+++++g++D
     EEA22167.1 190 VfgaPLDIKAvmgiPSMFVAGDQD 213
                    255533344444469999999988 PP

>> DUF5639  Family of unknown function (DUF5639)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0      0.16   5.8e+02      32      64 ..      63      95 ..      28      96 .. 0.77
   2 ?   10.3   0.1   0.00017      0.61      25      64 ..     148     184 ..     125     185 .. 0.88

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.16
                ESHHHHHHHHHHH-S..EE---EE-GGG-TT-E CS
     DUF5639 32 GhareveralealpgareveepldltplFPeGl 64
                G  r+    + +++  +e ++   l+plFP Gl
  EEA22167.1 63 GSGRNPYTLRREFSTFAETHSCALLAPLFPVGL 95
                5556655666777777788888889999*9997 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00017
                 EEEEEEEESHHHHHHHHHHH-S..EE---EE-GGG-TT-E CS
     DUF5639  25 elhllHFGhareveralealpgareveepldltplFPeGl 64 
                  +h + + h+r v++ +   pg    ++ l+++++FP+G+
  EEA22167.1 148 FVHRFAYLHPRRVRALACGAPGT---QTFLNFSQRFPDGV 184
                 47899999******988888885...899**********7 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0     5e-05      0.18      49     102 ..     119     173 ..     102     241 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 5e-05
                   HHHHHHHHHTT.S--GGGEEEEEETHHHHHHHHHHHH-GGG-SEEEEESE---CC CS
  Peptidase_S9  49 iaaaealakeg.yvdserlaitGgSyGGyltgaalnqrpdlFkaavaevpvvdvl 102
                   + +++++a+++  +d++  +++G S GG+ +   +  +p++ +a+++++p +   
    EEA22167.1 119 LSMIDEAAARFrRIDTSAFCLYGYSGGGQFVHRFAYLHPRRVRALACGAPGTQTF 173
                   467899999999********************99999****99999999977655 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   8.6e-05      0.31      71     114 ..     127     173 ..     111     213 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 8.6e-05
  Hydrolase_4  71 eehpel...plfllGhSmGGliallyllrypdkvaglilsaPalkik 114
                  ++ ++     + l+G S GG  + +++  +p++v++l + aP  +  
   EEA22167.1 127 ARFRRIdtsAFCLYGYSGGGQFVHRFAYLHPRRVRALACGAPGTQTF 173
                  4444433447889*****************************98765 PP

>> DUF1100  Alpha/beta hydrolase of unknown function (DUF1100)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.0   8.9e-05      0.32     256     299 ..     130     173 ..      78     186 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 8.9e-05
     DUF1100 256 pyvdhtrvgliGfrfGanvavrlaflesekvkavvalGavvhdl 299
                   +d    +l G+  G+  + r+a+l + +v+a ++  +   ++
  EEA22167.1 130 RRIDTSAFCLYGYSGGGQFVHRFAYLHPRRVRALACGAPGTQTF 173
                 5578888999************************9955544444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (291 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       275  (0.0153383); expected 358.6 (0.02)
Passed bias filter:                      267  (0.0148921); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2076.51
//
Query:       EEA22168.1  [L=669]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.8e-05   24.3  18.8       0.14   12.6   0.2    5.1  5  zf-C2H2      Zinc finger, C2H2 type
  ------ inclusion threshold ------
      0.011   15.9   2.4       0.17   12.0   3.0    2.1  2  YL1          YL1 nuclear protein
      0.088   13.7  18.7        1.1   10.3   0.3    5.0  4  zf-C2H2_4    C2H2-type zinc finger
       0.19   12.4   7.8        1.5    9.5   1.0    3.6  3  FOXP-CC      FOXP coiled-coil domain
       0.29   11.6   1.9        6.6    7.3   0.6    3.0  2  zf-met       Zinc-finger of C2H2 type
        6.2    7.2   6.6          5    7.5   0.6    3.2  3  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.2   4.8e-05      0.14       2      23 .]     274     294 ..     274     294 .. 0.94
   2 !    6.0   1.4    0.0062        19       2      23 .]     301     327 ..     301     327 .. 0.94
   3 !    9.1   0.1   0.00066         2       2      23 .]     333     362 ..     332     362 .. 0.93
   4 ?   -3.1   0.1       4.7   1.4e+04       5      15 ..     370     380 ..     369     382 .. 0.82
   5 !    7.0   0.3     0.003         9       2      20 ..     397     415 ..     397     416 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 4.8e-05
                 EET..TTTEEESSHHHHHHHHHCC CS
     zf-C2H2   2 kCp..dCgksFkrksnLkrHirtH 23 
                 +Cp  dCg+sF    +Lk+H+ tH
  EEA22168.1 274 RCPwpDCGRSF---KDLKAHMLTH 294
                 69999******...99*****999 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.0062
                 EET..TTT...EEESSHHHHHHHHHCC CS
     zf-C2H2   2 kCp..dCg...ksFkrksnLkrHirtH 23 
                 kCp   C    k F rk++ +rH  tH
  EEA22168.1 301 KCPilNCEyhlKGFARKYDKNRHTLTH 327
                 69999999999***************9 PP

  == domain 3  score: 9.1 bits;  conditional E-value: 0.00066
                 EETTTT.......EEESSHHHHHHHHHC.C CS
     zf-C2H2   2 kCpdCg.......ksFkrksnLkrHirt.H 23 
                 +C+ C+       ksF+r + +krH+++ H
  EEA22168.1 333 VCGFCPgsgsaaeKSFNRADVFKRHLMSvH 362
                 6999999999999*************9988 PP

  == domain 4  score: -3.1 bits;  conditional E-value: 4.7
                 TTTEEESSHHH CS
     zf-C2H2   5 dCgksFkrksn 15 
                  C k+ +++s+
  EEA22168.1 370 NCRKRSPTSSS 380
                 79999999986 PP

  == domain 5  score: 7.0 bits;  conditional E-value: 0.003
                 EETTTTEEESSHHHHHHHH CS
     zf-C2H2   2 kCpdCgksFkrksnLkrHi 20 
                 kC+ C+ +F++  ++  H+
  EEA22168.1 397 KCSTCSATFSNAQDFYEHL 415
                 7*************99996 PP

>> YL1  YL1 nuclear protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0      0.16   4.9e+02      26      45 ..      57      79 ..      34     157 .. 0.78
   2 ?   12.0   3.0   5.7e-05      0.17      15     135 ..     423     548 ..     420     564 .. 0.54

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.16
                x...xxxxxxxxxxxxxxxxxxx RF
         YL1 26 l...lFaEeedDeefeseeeeee 45
                +    ++E+  D ef+++++ ++
  EEA22168.1 57 EsssSWTEQTPDMEFQQKQQHQQ 79
                3555899999999**99988765 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 5.7e-05
                 xxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxx.xxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxx... RF
         YL1  15 leqeeeedelel.lFaEeedDeefeseeeeeeeensDsdf....dsdeedee.sdeeedeeegekelerqerkkr.....kkekkkrkaqkkkskk... 99 
                 ++qee+ + +++   aE ++De+ +   e+++    D       d+  ede  +d+++ ++++e ++++ ++  r          k+++qk++s+    
  EEA22168.1 423 VQQEEPSEAINQkRLAEVANDEDVKLTMEKHKL--LDTASpvgsDEYNEDELnDDADDADDADESNINNLNKDGRsgkgsL---SKSNSQKSSSRVvlg 516
                 788999999998899**********99888776..5544455443333333366677777788888887777777552431...333333333333000 PP

                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         YL1 100 kkkkqkkkkkkkidpqakeprpkkkseraswlpaes 135
                 ++++ +k+k + i +     r +++s  +sw + ++
  EEA22168.1 517 ANSAVSKNKPRAITR----RRGNRNSYPQSWGTPAA 548
                 332222222222222....23333333344443333 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.3   0.00037       1.1       2      23 ..     274     294 ..     273     295 .. 0.86
   2 ?    3.0   0.8     0.082   2.4e+02       2      23 ..     306     327 ..     302     328 .. 0.92
   3 ?    1.6   1.4      0.23     7e+02       8      24 .]     346     362 ..     333     362 .. 0.82
   4 ?    8.4   0.1    0.0015       4.5       2      20 ..     397     415 ..     397     417 .. 0.93

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00037
   zf-C2H2_4   2 kCpi..CgksFsskkaLlrHlkth 23 
                 +Cp+  Cg+sF++ ka   H++th
  EEA22168.1 274 RCPWpdCGRSFKDLKA---HMLTH 294
                 688888*****99999...99988 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.082
   zf-C2H2_4   2 kCpiCgksFsskkaLlrHlkth 23 
                  C++  k F +k++ +rH +th
  EEA22168.1 306 NCEYHLKGFARKYDKNRHTLTH 327
                 599999********999*9999 PP

  == domain 3  score: 1.6 bits;  conditional E-value: 0.23
   zf-C2H2_4   8 ksFsskkaLlrHlkthH 24 
                 ksF++ + ++rHl ++H
  EEA22168.1 346 KSFNRADVFKRHLMSVH 362
                 789777779****9999 PP

  == domain 4  score: 8.4 bits;  conditional E-value: 0.0015
   zf-C2H2_4   2 kCpiCgksFsskkaLlrHl 20 
                 kC+ C+++Fs+ +++  Hl
  EEA22168.1 397 KCSTCSATFSNAQDFYEHL 415
                 7**************9997 PP

>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   1.0    0.0005       1.5       5      26 ..     273     295 ..     271     312 .. 0.79
   2 ?    1.7   0.0      0.14   4.1e+02      13      45 ..     345     376 ..     334     385 .. 0.74
   3 ?    2.9   0.2     0.058   1.7e+02      11      28 ..     400     417 ..     394     457 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.0005
     FOXP-CC   5 gvCkWPgCekvledve.eflkhl 26 
                   C WP+C + ++d++ ++l h 
  EEA22168.1 273 RRCPWPDCGRSFKDLKaHMLTHQ 295
                 68***********9872455554 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.14
     FOXP-CC  13 ekvledveeflkhlnseHalddkstaqlrvqmq 45 
                 ek ++ ++ f +hl s H ++ +++  +r ++ 
  EEA22168.1 345 EKSFNRADVFKRHLMSVHGVE-QTAPNCRKRSP 376
                 778899999*********986.45566666655 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.058
     FOXP-CC  11 gCekvledveeflkhlns 28 
                  C++ ++++++f++hl++
  EEA22168.1 400 TCSATFSNAQDFYEHLDD 417
                 599************985 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.0       0.1   3.1e+02       8      21 ..     346     359 ..     345     360 .. 0.89
   2 ?    7.3   0.6    0.0022       6.6       3      20 ..     398     415 ..     397     416 .. 0.94

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.1
      zf-met   8 vtfnsesqlksHlq 21 
                 ++fn   ++k Hl 
  EEA22168.1 346 KSFNRADVFKRHLM 359
                 89**********95 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0022
      zf-met   3 CelCnvtfnsesqlksHl 20 
                 C+ C  tf++ +++  Hl
  EEA22168.1 398 CSTCSATFSNAQDFYEHL 415
                 **************9998 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.1       1.7   5.2e+03      12      23 ..     285     293 ..     280     295 .. 0.57
   2 ?    1.7   0.1      0.12   3.5e+02       9      21 ..     346     358 ..     345     360 .. 0.91
   3 ?    7.5   0.6    0.0017         5       4      21 ..     398     415 ..     397     416 .. 0.92

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 1.7
                  SSHHHHHCCTTS CS
  zf-C2H2_jaz  12 ksenaldnHlkS 23 
                  k   +l++H+ +
   EEA22168.1 285 K---DLKAHMLT 293
                  4...46666655 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.12
                  BBBSSHHHHHCCT CS
  zf-C2H2_jaz   9 KyFksenaldnHl 21 
                  K F+ + +++ Hl
   EEA22168.1 346 KSFNRADVFKRHL 358
                  99**********7 PP

  == domain 3  score: 7.5 bits;  conditional E-value: 0.0017
                  BTTTTBBBSSHHHHHCCT CS
  zf-C2H2_jaz   4 CvlCdKyFksenaldnHl 21 
                  C +C+ +F++++++ +Hl
   EEA22168.1 398 CSTCSATFSNAQDFYEHL 415
                  *************98886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (669 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1115  (0.0621897); expected 358.6 (0.02)
Passed bias filter:                      556  (0.0310112); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.44
# Mc/sec: 4586.26
//
Query:       EEA22169.1  [L=563]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-91  306.4   0.1    1.7e-91  305.8   0.1    1.3  1  DUF3431   Protein of unknown function (DUF3431)


Domain annotation for each model (and alignments):
>> DUF3431  Protein of unknown function (DUF3431)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  305.8   0.1   9.6e-96   1.7e-91       1     215 []     236     454 ..     236     454 .. 0.97

  Alignments for each domain:
  == domain 1  score: 305.8 bits;  conditional E-value: 9.6e-96
     DUF3431   1 lVvaklkeedtsWveeel..pdlqtaiYvvddpsaeltvpankGreamaYltyiidnYdsLpdvvvFvhahraawhndal.dydnaallrrlrleavqe 96 
                 lV+ak+k+edt+W+e++l  +d++ +iYvvddp+a l+ p+nkG+eam+YltyiidnYd+Lpd+++F+hah++awhn+++ + d++++lrrl+le+v++
  EEA22169.1 236 LVIAKTKKEDTAWTESKLegSDWDVSIYVVDDPTAPLHPPKNKGHEAMVYLTYIIDNYDNLPDIMAFMHAHQFAWHNEEIfELDAVEMLRRLSLERVTR 334
                 8***************664489*********************************************************99****************** PP

     DUF3431  97 eGYvnlrckwepgCpaelkple.keeeekkeeealaeafaelfeeeevpevvaapcCaqFavsrerirkrpreeYvrlrqwlletelddelsGrvleyl 194
                 eGY+n+rc+w+pgCp++l+p   +e+  kkee+ +++a++e+f++ ++p+v+++pcCaqF++srer+r+ pr ++v++rqwl++t+++d++sGrv+ey+
  EEA22169.1 335 EGYMNMRCHWSPGCPDHLRPGViDEDIGKKEERLITKAWSEIFPGMDIPQVLSQPCCAQFVLSRERVRTIPRGRFVHYRQWLINTDMRDTMSGRVWEYI 433
                 *******************99855557788888****************************************************************** PP

     DUF3431 195 WhilFgkeavaCpdeeecycd 215
                 Wh++F++++v+Cp+++ c+cd
  EEA22169.1 434 WHLVFTGQEVSCPSQNACLCD 454
                 ********************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (563 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       459  (0.025601); expected 358.6 (0.02)
Passed bias filter:                      400  (0.0223102); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.42
# Mc/sec: 4071.76
//
Query:       EEA22170.1  [L=779]
Description: RING finger protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.6e-10   41.1   3.7    2.8e-10   40.3   3.7    1.4  1  zf-rbx1       RING-H2 zinc finger domain
    4.6e-08   33.3   7.8    1.5e-07   31.7   7.8    1.8  1  zf-RING_2     Ring finger domain
    3.1e-07   30.2   2.3    5.4e-07   29.4   2.3    1.4  1  zf-C3HC4      Zinc finger, C3HC4 type (RING finger)
    1.2e-05   25.2   1.5    2.3e-05   24.3   1.5    1.5  1  zf-RING_UBOX  RING-type zinc-finger
    2.4e-05   24.1   6.5    0.00013   21.8   2.5    2.2  2  zf-C3HC4_3    Zinc finger, C3HC4 type (RING finger)
    5.6e-05   23.0   2.5     0.0002   21.2   2.7    1.8  2  zf-RING_5     zinc-RING finger domain
      8e-05   22.4   3.4     0.0002   21.2   3.4    1.6  1  zf-C3HC4_2    Zinc finger, C3HC4 type (RING finger)
    0.00016   21.2   1.0    0.00034   20.2   1.0    1.4  1  Zn_ribbon_17  Zinc-ribbon, C4HC2 type
     0.0018   18.3   4.5     0.0078   16.2   4.5    1.9  1  zf-ANAPC11    Anaphase-promoting complex subunit 11 RING-H2 f
     0.0058   16.5   5.5      0.016   15.0   5.6    1.7  1  Prok-RING_4   Prokaryotic RING finger family 4
  ------ inclusion threshold ------
      0.052   13.3   2.3       0.46   10.3   0.3    2.4  2  zf-RING_11    RING-like zinc finger
       0.08   13.1   0.9       0.16   12.2   0.9    1.5  1  zf-C3HC4_4    zinc finger of C3HC4-type, RING
       0.33   11.7   1.1         21    5.9   0.3    2.5  2  zf-3CxxC_2    Zinc-binding domain
        3.1    8.0   4.1         17    5.7   4.1    2.1  1  FANCL_C       FANCL C-terminal domain


Domain annotation for each model (and alignments):
>> zf-rbx1  RING-H2 zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.3   3.7   2.2e-13   2.8e-10       1      55 []     340     398 ..     340     398 .. 0.76

  Alignments for each domain:
  == domain 1  score: 40.3 bits;  conditional E-value: 2.2e-13
     zf-rbx1   1 dtCaiCrneleeacieckapgdee.....cpvvlGeCgHaFHlhCiskWlktrkvCPlcr 55 
                 dtC+iCr+e+  ++ +   +g+++       ++   CgH  H+ C+++Wl+++++CP+cr
  EEA22170.1 340 DTCIICREEMV-PWQQPAGEGNRRavperLRPKKLPCGHILHFACLRSWLERQQNCPMCR 398
                 79*****8876.34444444444445778555556************************8 PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.7   7.8   1.1e-10   1.5e-07       2      44 .]     341     398 ..     340     398 .. 0.81

  Alignments for each domain:
  == domain 1  score: 31.7 bits;  conditional E-value: 1.1e-10
   zf-RING_2   2 eCpICleelssads...............vlllpCgHvfhreClerwlrssstCPlCr 44 
                 +C IC ee+ + ++               + +lpCgH+ h+ Cl+ wl+++++CP+Cr
  EEA22170.1 341 TCIICREEMVPWQQpagegnrravperlrPKKLPCGHILHFACLRSWLERQQNCPMCR 398
                 7999999996666666677778876664333779***********************9 PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.4   2.3   4.2e-10   5.4e-07       1      41 []     342     397 ..     342     397 .. 0.95

  Alignments for each domain:
  == domain 1  score: 29.4 bits;  conditional E-value: 4.2e-10
                 -TTT-S--SS-E..................E-TTS--B-CHHHHHHHHCTSSB--TTT CS
    zf-C3HC4   1 CpiCleeakepn.................elleCkHsfCskCirkilksrkkvkCPlC 41 
                 C+iC ee++  +                 + l+C+H ++++C+r++l+  ++++CP+C
  EEA22170.1 342 CIICREEMVPWQqpagegnrravperlrpKKLPCGHILHFACLRSWLE--RQQNCPMC 397
                 9*****999888899*********************************..8899**** PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.3   1.5   1.8e-08   2.3e-05       1      39 []     342     395 ..     342     395 .. 0.93

  Alignments for each domain:
  == domain 1  score: 24.3 bits;  conditional E-value: 1.8e-08
  zf-RING_UBOX   1 CpIClelft..................dPlvlpCGHtFCreClwelskslegafkCP 39 
                   C IC+e++                   +P++lpCGH+++  Cl   +++le++  CP
    EEA22170.1 342 CIICREEMVpwqqpagegnrravperlRPKKLPCGHILHFACL---RSWLERQQNCP 395
                   99****999999**********9999999558***********...999*******9 PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.1     0.043        55      35      46 ..     337     348 ..     332     350 .. 0.76
   2 !   21.8   2.5   9.9e-08   0.00013      18      47 ..     373     401 ..     369     402 .. 0.95

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.043
                 HTT-B-TTT--B CS
  zf-C3HC4_3  35 krkkkCpiCrrp 46 
                 +r+++C iCr++
  EEA22170.1 337 AREDTCIICREE 348
                 478899999987 PP

  == domain 2  score: 21.8 bits;  conditional E-value: 9.9e-08
                 TTEEEEEE-HHHHHHHHHTT-B-TTT--B- CS
  zf-C3HC4_3  18 lpCgHlvlCeeCaekllkrkkkCpiCrrpi 47 
                 lpCgH+ l  +C++++l+r+++Cp+Crrp+
  EEA22170.1 373 LPCGHI-LHFACLRSWLERQQNCPMCRRPV 401
                 7*****.*********************97 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.2      0.38   4.8e+02      34      43 ..     337     346 ..     328     347 .. 0.80
   2 !   21.2   2.7   1.6e-07    0.0002       2      44 .]     342     399 ..     341     399 .. 0.84

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.38
   zf-RING_5  34 ekeavCpiCr 43 
                 ++e++C iCr
  EEA22170.1 337 AREDTCIICR 346
                 6789*****8 PP

  == domain 2  score: 21.2 bits;  conditional E-value: 1.6e-07
   zf-RING_5   2 CnkCfekl...............skeekfyltsCgHifCekClkkllekeavCpiCrk 44 
                 C +C+e++                ++ ++  ++CgHi++ +Cl+  le++++Cp+Cr+
  EEA22170.1 342 CIICREEMvpwqqpagegnrravPERLRPKKLPCGHILHFACLRSWLERQQNCPMCRR 399
                 8899999999988888655555555555999*************************95 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   3.4   1.5e-07    0.0002      17      40 .]     374     397 ..     367     397 .. 0.94

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 1.5e-07
  zf-C3HC4_2  17 pCgHvfCqkCilrsLeekneCPlC 40 
                 pCgH  +  C++ +Le++++CP+C
  EEA22170.1 374 PCGHILHFACLRSWLERQQNCPMC 397
                 9*********************** PP

>> Zn_ribbon_17  Zinc-ribbon, C4HC2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   1.0   2.7e-07   0.00034      24      46 ..     375     395 ..     371     398 .. 0.88

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 2.7e-07
  Zn_ribbon_17  24 CeHvlHasCarewfenddlaeCp 46 
                   C+H+lH++C+r+w+e ++  +Cp
    EEA22170.1 375 CGHILHFACLRSWLERQQ--NCP 395
                   ***************998..777 PP

>> zf-ANAPC11  Anaphase-promoting complex subunit 11 RING-H2 finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   4.5   6.1e-06    0.0078      18      81 ..     336     401 ..     329     405 .. 0.62

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 6.1e-06
                 -SSSSB-TTT-SBT...T...S--TTCSTTTTTS-EEEBT..TS-EEEHHHHHHHHHHHSTSSB-TTTSSB- CS
  zf-ANAPC11  18 vasddvcGicrvsf...d...GtcpsckfpGddcplvlGk..ckhnfhlhcilkwletetskglcpmcrqtf 81 
                 +a++d+c icr +    +   G      +p    p    k  c h++h  c+  wle+   +++cpmcr+ +
  EEA22170.1 336 IAREDTCIICREEMvpwQqpaGEGNRRAVPERLRPK---KlpCGHILHFACLRSWLER---QQNCPMCRRPV 401
                 677888888885431112111222222333333332...234**************97...578*****865 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   5.6   1.3e-05     0.016      14      39 ..     373     400 ..     342     404 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.3e-05
  Prok-RING_4  14 epCgHlvCkeCfdsk..dlssCPlCqrr 39 
                   pCgH++  +C+ s+    + CP+C+r 
   EEA22170.1 373 LPCGHILHFACLRSWleRQQNCPMCRRP 400
                  69************9855559*****96 PP

>> zf-RING_11  RING-like zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.1      0.11   1.4e+02       2      13 ..     342     353 ..     341     355 .. 0.90
   2 ?   10.3   0.3   0.00036      0.46      17      29 .]     372     384 ..     365     384 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.11
  zf-RING_11   2 CsICLeefkpgq 13 
                 C IC ee+ p q
  EEA22170.1 342 CIICREEMVPWQ 353
                 ********9987 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00036
  zf-RING_11  17 ilpCsHtFHfkCI 29 
                  lpC+H+ Hf C+
  EEA22170.1 372 KLPCGHILHFACL 384
                 68**********5 PP

>> zf-C3HC4_4  zinc finger of C3HC4-type, RING
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.9   0.00012      0.16      11      42 .]     370     397 ..     368     397 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00012
  zf-C3HC4_4  11 PvsleCGhsfClsCisslqkepdgeqllCplC 42 
                 P  l+CGh+  + C+ s+ + +++    Cp+C
  EEA22170.1 370 PKKLPCGHILHFACLRSWLERQQN----CPMC 397
                 8899***********999988855....9999 PP

>> zf-3CxxC_2  Zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.1     0.068        88      28      52 ..     340     364 ..     336     383 .. 0.78
   2 ?    5.9   0.3     0.016        21      22      44 ..     386     409 ..     374     432 .. 0.72

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.068
  zf-3CxxC_2  28 QeCkkCkekvepyklrekdkkkgaa 52 
                  +C+ C+e+++p+++   +++ +a+
  EEA22170.1 340 DTCIICREEMVPWQQPAGEGNRRAV 364
                 68************98866555554 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.016
  zf-3CxxC_2  22 afaneaQeCkkCkekve.pyklre 44 
                 ++ ++ Q+C  C+  v+ p +++ 
  EEA22170.1 386 SWLERQQNCPMCRRPVVvPRNQQY 409
                 8************99752555443 PP

>> FANCL_C  FANCL C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   4.1     0.013        17      25      46 ..     372     393 ..     338     405 .. 0.71

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.013
                 -TT----B-SGGGHHHHHHHHS CS
     FANCL_C  25 nekCnkkfHsaCLkeWlrslke 46 
                    C+++ H aCL  Wl+ +++
  EEA22170.1 372 KLPCGHILHFACLRSWLERQQN 393
                 456**************98764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (779 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1304  (0.0727313); expected 358.6 (0.02)
Passed bias filter:                      835  (0.0465726); expected 358.6 (0.02)
Passed Vit filter:                       110  (0.00613531); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.76u 0.31s 00:00:01.07 Elapsed: 00:00:00.46
# Mc/sec: 5061.40
//
Query:       EEA22171.1  [L=570]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.9e-19   69.2  35.2    2.7e-10   39.7   3.8    3.1  3  MFS_1       Major Facilitator Superfamily
    5.5e-05   22.2   0.2       0.18   10.6   1.3    3.0  2  MFS_1_like  MFS_1 like family
  ------ inclusion threshold ------
      0.059   12.1   0.1      0.099   11.4   0.1    1.3  1  DUF2206     Predicted membrane protein (DUF2206)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.7   8.4   3.7e-13   2.2e-09       3     116 ..      27     139 ..      26     144 .. 0.92
   2 !   39.7   3.8   4.6e-14   2.7e-10     120     322 ..     189     446 ..     180     468 .. 0.62
   3 !    5.0   7.1    0.0017        10     124     167 ..     514     557 ..     508     570 .] 0.87

  Alignments for each domain:
  == domain 1  score: 36.7 bits;  conditional E-value: 3.7e-13
       MFS_1   3 laaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.sslw.lllvlrvlqGlga 99 
                  +afl++l++s+ +++   +++ + g  ++++g l  +  l+a++a + +G lsd++G r v  +g+++ al+ l+l++  s+++  ll++r+  +lg+
  EEA22171.1  27 SIAFLVFLNSSVSFVVTD-LIGLEKG-EGDAVGSLGFADELLALIACPAWGLLSDKIGVRYVCTIGYTIIALS-LVLFVQaSNIYpQLLLSRLSFSLGG 122
                 6899*******9999999.9****99.**********************************************.6666324**999************* PP

       MFS_1 100 galfpagaaliadwfpk 116
                 +a+++++ a +  ++ +
  EEA22171.1 123 SAVATMVTATLPTITGG 139
                 **********9998865 PP

  == domain 2  score: 39.7 bits;  conditional E-value: 4.6e-14
       MFS_1 120 graigllsagfslGailgpllggllasslg.........Wravfyilaivsllafv.lfllll............peepperkrkspkeee........ 188
                 +r  g++++++++Ga++  ++   l +++           + +fyi+a v+ll++v +f+ +             +              +        
  EEA22171.1 189 SRLAGFVGLFAGCGALISLAVFLPLPAYFErsgsspahaIQKSFYIVASVALLVAVaCFFGFRnlpgeeekriqaL--------------Wqgtqpdee 273
                 5566677777777776664444433334444456998888888***********9955333334444433333330..............333444444 PP

       MFS_1 189 ........kgtgpaplvpawkallkdpvlw.illialllfffgfsglltllpl...ylqevlgls......................glllaglllall 253
                         +   ++ l+ a+k+ +++p +   ++ +l+  +    +++ ++pl   y   +lgl                       +++la++l +++
  EEA22171.1 274 ypgyrpstVTGYGKDLLHAFKLGFRHPDIClGYVGGLVARG-SSVAISLFIPLvvnYYYRRLGLCqrtdadkppsgdlgdiktscpeAYILASILTGVS 371
                 4444444433377777779********88423333333333.45558888888555324444444777777****************99********** PP

       MFS_1 254 alvgailallagrlsdrlgrrrrlllallllllaalglallavt........ssavllllvlvl...iGfglgfvfpsll 322
                 +lv++  a+++g+ls r  +rr+++  l+++ll+++g++ ++++        +   ++  v+v+   iG+ +  + +++l
  EEA22171.1 372 QLVALLTAPIFGYLSER--SRRYNIPLLFAALLGVVGYIAFPLIfspqlkapH---VSGGVFVMasfIGISQIGAIVCSL 446
                 ***************88..4555555555555555555555555444774432...333333332225664444444444 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.0017
       MFS_1 124 gllsagfslGailgpllggllasslgWravfyilaivsllafvl 167
                 g++s+  ++G+++   lggll +  +  a+fyi+a++  ++f+ 
  EEA22171.1 514 GIYSLYGGAGILILTKLGGLLFDVSSTGAPFYIMAFFNGILFLA 557
                 899999***********************************993 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.1   0.0   0.00036       2.2      36      86 ..      56     103 ..      50     249 .. 0.71
   2 !   10.6   1.3     3e-05      0.18      37      86 ..     365     414 ..     360     562 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.00036
  MFS_1_like  36 igiitlilpltsilsppiwgvlaDrfgkrkkvvilslllsavlflsllfip 86 
                 +g +  +  l+++++ p wg l+D++g r     ++  + a+  + +lf+ 
  EEA22171.1  56 VGSLGFADELLALIACPAWGLLSDKIGVRYV-CTIGYTIIAL--SLVLFVQ 103
                 666667778999**************98864.2222222222..2223333 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 3e-05
  MFS_1_like  37 giitlilpltsilsppiwgvlaDrfgkrkkvvilslllsavlflsllfip 86 
                  i+t +  l+++l +pi+g l++r+++++  +++++ll +v ++++ +i 
  EEA22171.1 365 SILTGVSQLVALLTAPIFGYLSERSRRYNIPLLFAALLGVVGYIAFPLIF 414
                 5899***********************************99999877665 PP

>> DUF2206  Predicted membrane protein (DUF2206)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.1   1.7e-05     0.099     147     207 ..     360     421 ..     353     485 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 1.7e-05
     DUF2206 147 eylaivlvl.lvilvasivlpyfasalntaRlyqilliflapffiiGgialiklikkvikks 207
                  y+++++++ +  lva++++p f+   + +R y+i l+f a + ++G+ia++ +++  +k+ 
  EEA22171.1 360 AYILASILTgVSQLVALLTAPIFGYLSERSRRYNIPLLFAALLGVVGYIAFPLIFSPQLKAP 421
                 566665554256799********999999*********************998887775554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (570 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       477  (0.0266049); expected 358.6 (0.02)
Passed bias filter:                      285  (0.015896); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.31s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 3674.40
//
Query:       EEA22172.1  [L=366]
Description: bis(5'-nucleosyl)-tetraphosphatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.1e-24   84.5   0.1    1.9e-23   82.4   0.0    2.2  3  ATP_transf  ATP adenylyltransferase


Domain annotation for each model (and alignments):
>> ATP_transf  ATP adenylyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0      0.48   8.6e+03       3      33 ..       2      30 ..       2      34 .. 0.65
   2 ?   -2.9   0.0      0.44   7.9e+03      11      21 ..     240     249 ..     237     257 .. 0.66
   3 !   82.4   0.0     1e-27   1.9e-23       1      66 []     293     364 ..     293     364 .. 0.98

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 0.48
  ATP_transf  3 NllmtkewmvviPRsaegaeleevgglslNs 33
                Nl +t++   ++ R+   a+  e+g+l + +
  EEA22172.1  2 NLGLTESLPSLVSRRFTAAK--ESGSLLFSA 30
                78888888888889855555..456655555 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.44
  ATP_transf  11 mvviPRsaega 21 
                  + iPRs e++
  EEA22172.1 240 AMQIPRS-ESS 249
                 5779**9.444 PP

  == domain 3  score: 82.4 bits;  conditional E-value: 1e-27
  ATP_transf   1 sYNllmtkewmvviPRsaegaele.....evgglslNslglaGtllvkseeeldalkeepgpl.evLaevGv 66 
                 sYNl+mt++ m+++PR++e+a+l+     ++ ++slN+++laGtl+vk+ee++d l+ + +++ ++LaevG+
  EEA22172.1 293 SYNLAMTRDIMMICPRRKETATLSglgadSAADVSLNGTILAGTLMVKTEEQWDCLRGDGEVVnDLLAEVGI 364
                 8********************************************************9999*********96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (366 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       435  (0.0242624); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2544.66
//
Query:       EEA22173.1  [L=565]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
  ------ inclusion threshold ------
      0.035   14.1  14.6      0.065   13.2  14.6    1.4  1  Trypan_PARP  Procyclic acidic repetitive protein (PARP)


Domain annotation for each model (and alignments):
>> Trypan_PARP  Procyclic acidic repetitive protein (PARP)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2  14.6   3.6e-06     0.065      69     108 ..      49      88 ..      35     104 .. 0.51

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 3.6e-06
  Trypan_PARP  69 pepepepepepetepeeepepepepepepepepepepepe 108
                  p  ep p+ epe +pe++pep  epe e e+ep p  e +
   EEA22173.1  49 PSAEPTPKSEPEHQPEHQPEPGHEPEHESESEPSPPQEIK 88 
                  2233333333333455555555555555555555444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (565 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       369  (0.0205812); expected 358.6 (0.02)
Passed bias filter:                      244  (0.0136092); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.23s 00:00:00.81 Elapsed: 00:00:00.42
# Mc/sec: 4044.52
//
Query:       EEA22174.1  [L=470]
Description: COP9 signalosome subunit 1 (CsnA), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.8e-46  157.0   0.0    7.2e-46  156.1   0.0    1.5  1  RPN7      26S proteasome subunit RPN7
    1.2e-13   51.5   0.1    2.9e-12   47.0   0.0    2.8  3  PCI       PCI domain


Domain annotation for each model (and alignments):
>> RPN7  26S proteasome subunit RPN7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  156.1   0.0   8.1e-50   7.2e-46       1     173 [.     108     283 ..     108     284 .. 0.96

  Alignments for each domain:
  == domain 1  score: 156.1 bits;  conditional E-value: 8.1e-50
                 -HHHHHHHHHHHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHCT-HHHHHHHHHTCCCC--SHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHH CS
        RPN7   1 DekwveelrkknekeleeLdaelkdakenlgkeeirrakldlaehYlkigdleeAlkaysrireyctslkhkidmllnlirvaiffndwdlvskyleka 99 
                 D++wv+ +++++++e+++L++elk++k+nl+ke+ir++ +dla hY+ +gdl++A kay+r+ + ct+++h + m l+ i vai ++dw  v + +++ 
  EEA22174.1 108 DQRWVDVTKQTVRAETDKLEHELKGYKNNLIKESIRMGTDDLASHYHAVGDLASASKAYARLKDNCTTPSHFAAMHLKTINVAIDRGDWFGVLQAVARY 206
                 99************************************************************************************************* PP

                 HCSSS---..HHHHHHHHHHHHHHHHHTT-HHHHHHHHCTS-GGGT...TTT--HHHHHHHHHHHHHHH--HHHHHH CS
        RPN7 100 kellekggd.werknrlkvyeGlallairkfkeAaellldilstfts..kellsyedlavyavlcalatldRkdLka 173
                 ++  +  ++  +  ++++ ++Gla+l +++f +A++ +l +++t+++  +e+l+ +d+avy++lcala++dR++L++
  EEA22174.1 207 RSGPKPEDEqSKNAAKISSASGLAQLGQGNFLDATNQFLGSEPTLGDsyNEVLTANDVAVYGGLCALASMDRNELQR 283
                 ***998444245566888899************************99****************************97 PP

>> PCI  PCI domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0      0.46   4.1e+03       5      48 ..     113     139 ..      76     148 .. 0.55
   2 !   47.0   0.0   3.3e-16   2.9e-12       2     104 ..     300     413 ..     299     414 .. 0.94
   3 ?    1.4   0.1      0.05   4.5e+02      59      92 ..     415     448 ..     411     451 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.46
                 HHHHHHHHTSHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHH CS
         PCI   5 dllkalrsgnlsgfseelkdleeelladdglaqllesLekkvre 48 
                 d++k+ ++ + ++ ++elk                  +++++++
  EEA22174.1 113 DVTKQTVRAETDKLEHELKG-----------------YKNNLIK 139
                 33333333333444444444.................4444444 PP

  == domain 2  score: 47.0 bits;  conditional E-value: 3.3e-16
                 HHHHHHHHHHHTSHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHCESEEEHHHHHHHHTSSH...........HHHHHHHHHHHHTTS CS
         PCI   2 sysdllkalrsgnlsgfseelkdleeelladdglaqllesLekkvrerllrqvskiyssislerlaklldlsv...........devEkilvklIrdge 89 
                 ++++ ++ + ++++ ++  +l+++++++l d +l+ +++ L++++r+++++q++ ++s++sl+ +ak +  +v           +   + l+klI++g 
  EEA22174.1 300 HIRRAISFFCNSKFRACLDILEEYKADYLLDIHLQRHIPALYNQIRTKSIQQYAVPFSRVSLDAMAKVFAPKVvggvsspteigSPFVRELIKLIENGT 398
                 5667777788999999*****************************************************999999*********9999*********** PP

                 SSEEEETTTTEEEEC CS
         PCI  90 irakidqesgivvfk 104
                 ++a+id e+g++v k
  EEA22174.1 399 LDARIDLEKGLLVSK 413
                 ************987 PP

  == domain 3  score: 1.4 bits;  conditional E-value: 0.05
                 SEEEHHHHHHHHTSSHHHHHHHHHHHHHTTSSSE CS
         PCI  59 ssislerlaklldlsvdevEkilvklIrdgeira 92 
                 + ++ + + ++ld  ++ v +   +lIr++ i+a
  EEA22174.1 415 TDLRKDVIKEALDSVEEYVNEAHLRLIRTNIINA 448
                 5566778889999999999999999999999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (470 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       587  (0.0327403); expected 358.6 (0.02)
Passed bias filter:                      512  (0.0285571); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3235.19
//
Query:       EEA22175.1  [L=233]
Description: DSBA family oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.6e-23   81.7   0.0    6.3e-23   81.6   0.0    1.0  1  DSBA      DSBA-like thioredoxin domain
  ------ inclusion threshold ------
       0.11   12.0   0.1       0.17   11.3   0.1    1.2  1  DUF2336   Uncharacterised protein conserved in bacteria (DUF2
       0.21   11.5   0.0       0.28   11.0   0.0    1.1  1  DUF5311   Family of unknown function (DUF5311)


Domain annotation for each model (and alignments):
>> DSBA  DSBA-like thioredoxin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.6   0.0   1.1e-26   6.3e-23       2     192 ..       5     216 ..       4     217 .. 0.91

  Alignments for each domain:
  == domain 1  score: 81.6 bits;  conditional E-value: 1.1e-26
                 EEEEEBTTBHHHHHHHHHHHHHHHHC..CTEEEEEEE-SSSCHHHHCT.S.GGGSHHHHHHHHHHHHHHHHHHT.....GGSSHHHHHHHHHHHHHHHH CS
        DSBA   2 vdeffDvlCPyCylgkerleklaars..pdvkvvlrpfelagakkasgnvgpselpeklkylledlkrlaeaegi.plrfpkdklknstraarlllaag 97 
                 +  ++D ++Py+++++  l++++a     +v++  +p++l g +  sgn++p  +p+k k  + +l+r  +++++ p+++pk+++  +   +r+l++ +
  EEA22175.1   5 IHAYYDCVSPYSFFAFTHLQEVRAVLasHGVSIETHPIFLGGIMNGSGNQPPWLVPAKAKLGQLELERAIKYWKVePFKIPKIFPILTILPQRALTYIK 103
                 678*********************998777*********************************************77******999999********99 PP

                 HHH...GHHHHHHHHHHHHHTSSS-TSSHHHHHHHHH..HTTS.HHH....HHHHHTSHHHHHHHHHHHHHHHHTT-SSSSEEEE...TTC......EE CS
        DSBA  98 aeg...laekvvrelfealwsegqaitddqellevae..kaGldaee....ldealeseavkeavrentaaaqslgvtGvPtvvv...dgk......rm 178
                       + e+ +  +++ ++ + q+i++++ l+e++   +aG+++e+    l +a+ +++ ke++  +t+aa + g++G+P++ v   dg+        
  EEA22175.1 104 HTYptaQFENTAHLYWQWFLYKHQDISKPDILRELLAspEAGFSREQaeeiLTAAMTDKKWKEELTATTQAALDKGAFGAPFFWVvktDGHgrtvaeEP 202
                 99888899999999********************987447*******44555566777***************************99877555666678 PP

                 EESSSSHHHHHHHH CS
        DSBA 179 vfGadrldtladal 192
                 +fG+dr++++ ++l
  EEA22175.1 203 FFGSDRFHQMWEYL 216
                 9*******997766 PP

>> DUF2336  Uncharacterised protein conserved in bacteria (DUF2336)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   2.8e-05      0.17      53      90 ..     133     170 ..     128     177 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 2.8e-05
     DUF2336  53 evvrallaNpgAelseeslerlveragedealreaLlr 90 
                 + +r+lla p+A +s+e+ e+++  a++d +++e L++
  EEA22175.1 133 DILRELLASPEAGFSREQAEEILTAAMTDKKWKEELTA 170
                 66899******************************986 PP

>> DUF5311  Family of unknown function (DUF5311)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   4.8e-05      0.28      35      87 ..     117     170 ..      98     176 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 4.8e-05
     DUF5311  35 ifye.slvskpvisseeivsrllkiLetGysssvasllvselgadvalekelad 87 
                 ++++  l +++ is  +i+ +ll   e+G+s + a++ ++   +d  +++el++
  EEA22175.1 117 LYWQwFLYKHQDISKPDILRELLASPEAGFSREQAEEILTAAMTDKKWKEELTA 170
                 455514667899************************************999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (233 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       445  (0.0248201); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 1538.97
//
Query:       EEA22176.1  [L=315]
Description: short chain dehydrogenase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.5e-26   90.8   0.4    4.6e-17   62.1   0.0    2.1  2  adh_short     short chain dehydrogenase
    5.1e-20   72.0   0.2    2.9e-15   56.5   0.0    2.1  2  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
  ------ inclusion threshold ------
      0.077   12.9   0.0       0.13   12.2   0.0    1.4  1  KR            KR domain
        0.2   11.0   0.0        0.5    9.7   0.0    1.6  2  DUF1776       Fungal family of unknown function (DUF1776)


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.0   0.1   5.9e-10   2.6e-06       1      36 [.       4      39 ..       4      45 .. 0.89
   2 !   62.1   0.0     1e-20   4.6e-17      33     180 ..      54     206 ..      52     220 .. 0.93

  Alignments for each domain:
  == domain 1  score: 27.0 bits;  conditional E-value: 5.9e-10
                SEEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHH CS
   adh_short  1 kvvlvtGassGIGraiakelakeGakvvvvdrseek 36
                +v+lv+Gas+GIGr+ia  la++G+ vv+++++ ++
  EEA22176.1  4 QVALVIGASRGIGRQIAIDLARNGYAVVIAAKTTSN 39
                69***************************8887665 PP

  == domain 2  score: 62.1 bits;  conditional E-value: 1e-20
                 CHHHHHHHHHHHHHT.TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHH.HCTTE CS
   adh_short  33 seekleevakelkee.gakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfselseeewervievNltgvflltravlpaml.kqssG 129
                 s +++++va e+ ++ + +a+ai+vD +d ++++ lv++ v  +gkldvL+ N G  + ++++++  ++++ +  +N  g++  ++a+lpa+  ++ +G
  EEA22176.1  54 SHSTINTVAREITDLhNGTATAIAVDTRDVNQINFLVAETVRIYGKLDVLIYNSGAIWWSSVENTPVKRFQLMQRINPEGLYASVHAALPAFEkNGWRG 152
                 56788999******9999**************************************************************************977889* PP

                 EEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGT...EEEEEEEES CS
   adh_short 130 rIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptg...irvnavaPG 180
                 rI+ vs  +    + g +aY+  K ++  l++ la++++++g     ++++ P+
  EEA22176.1 153 RIIVVSPPIYSRFFRGKTAYAMGKIGMSVLSKGLAMDFERQGrkdMAITSIWPA 206
                 **************************************9998777777777775 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.7   0.0   7.7e-06     0.035       1      25 [.      10      34 ..      10      43 .. 0.90
   2 !   56.5   0.0   6.5e-19   2.9e-15      36     165 ..      64     196 ..      53     226 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 7.7e-06
                  TTTTSHHHHHHHHHHHTT-EEEEEE CS
  adh_short_C2  1 GaasgIGraiAkalaeeGaevvltd 25
                  Ga +gIGr+iA  la++G+ vv++ 
    EEA22176.1 10 GASRGIGRQIAIDLARNGYAVVIAA 34
                  999*******************986 PP

  == domain 2  score: 56.5 bits;  conditional E-value: 6.5e-19
                   HHHHHTT..SEEEE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHHHHHHHHTHHHHHHHHHHHHHCTSC...CEEEEEE CS
  adh_short_C2  36 elaeelg..aevlecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreefdraldvnlyslfllakaalplmkeg...gsivnls 127
                   e+++ ++  a+++++D +d +q++ lv+e+v+ +gklD+l+ n g      +++++t+ + f+ ++ +n  +l++ ++aalp+++++   g+i+ +s
    EEA22176.1  64 EITDLHNgtATAIAVDTRDVNQINFLVAETVRIYGKLDVLIYNSGAIWW--SSVENTPVKRFQLMQRINPEGLYASVHAALPAFEKNgwrGRIIVVS 158
                   333333321447*************************************..*******************************8888779******** PP

                   EGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEE CS
  adh_short_C2 128 svgaervvpnynaygaaKaalealtrylAvelgpkgiR 165
                       +r + + +ay++ K ++  l++ lA+++ ++g +
    EEA22176.1 159 PPIYSRFFRGKTAYAMGKIGMSVLSKGLAMDFERQGRK 196
                   ********************************999865 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   2.9e-05      0.13       3      83 ..       6     101 ..       4     128 .. 0.67

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2.9e-05
                 EEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS................--HHHHHHHHHHHHT.T-EEEE----TT-HHHHHHHHHHHHHHSS--- CS
          KR   3 ylitGGlGgLGlelarwlaekgarhlvllsRsa..............aadedskaliaeleal.gaevevvaaDvsdkdavealleeikaeeppik 83 
                  l++G+  g+G+++a  la++g + ++    ++              +++++ ++  +e+++l + + +++a+D  d ++++ l++e  +  +++ 
  EEA22176.1   6 ALVIGASRGIGRQIAIDLARNGYAVVIAAKTTSnphdpaipfppppnSSHSTINTVAREITDLhNGTATAIAVDTRDVNQINFLVAETVRIYGKLD 101
                 59********************65555444443477888888765543333334455666665344777778888887777777777766555555 PP

>> DUF1776  Fungal family of unknown function (DUF1776)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.0   0.00011       0.5       3      37 ..       3      36 ..       1      44 [. 0.84
   2 ?   -3.3   0.0         1   4.6e+03     128     157 ..     135     163 ..     113     165 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00011
     DUF1776  3 kdvvlvlGsptePltRsialDLerrGFiVfvtves 37
                k+v lv+G     + R+ia DL r G+ V++ ++ 
  EEA22176.1  3 KQVALVIGAS-RGIGRQIAIDLARNGYAVVIAAKT 36
                7899999965.569****************98765 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 1
     DUF1776 128 iltlqallplltsrakqkakiivvnpsiss 157
                 ++ + a lp ++++   + +iivv+p i s
  EEA22176.1 135 YASVHAALPAFEKNG-WRGRIIVVSPPIYS 163
                 566677778888754.78899999998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (315 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       381  (0.0212505); expected 358.6 (0.02)
Passed bias filter:                      357  (0.0199119); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 2083.55
//
Query:       EEA22177.1  [L=597]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.013   15.7   1.4       0.83    9.9   0.0    3.0  3  BTB       BTB/POZ domain


Domain annotation for each model (and alignments):
>> BTB  BTB/POZ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0   4.6e-05      0.83      37      80 ..      41      86 ..      34      99 .. 0.78
   2 ?    0.5   0.0      0.04   7.1e+02      86     110 ..     436     460 ..     433     461 .. 0.85
   3 ?    2.2   0.1     0.011     2e+02      60      89 ..     497     527 ..     478     543 .. 0.77

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 4.6e-05
                HHHHHTSTTTTTCCCEEEEETTSGHHHHHHHHHHHHHSEEEC-..C CS
         BTB 37 FkalftskeieessvseielddvepeafealLefiYtgeleit..s 80
                +++l+++++ +es+     l+d e e+f a+ +++Ytg+ +++  +
  EEA22177.1 41 LDDLMNNGHTRESKHRIAVLEDEEVEVFTAFTQYAYTGNYTVPvhK 86
                56788888566666667789*******************9998542 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.04
                 HHHHHHHHHT-HHHHHHHHHHHHHH CS
         BTB  86 elLaaadllqiprlkkaceeflkqs 110
                 ++   a ++ ip l+++c ++l +s
  EEA22177.1 436 KVYVFATRYLIPGLAQLCLQKLHTS 460
                 5667799************999876 PP

  == domain 3  score: 2.2 bits;  conditional E-value: 0.011
                 GHHHHHHHHHHHHHSEEEC-.CGGGHHHHHH CS
         BTB  60 epeafealLefiYtgeleit.seenleelLa 89 
                 +++ f  +L++ Y  +++++ ++++ + lL+
  EEA22177.1 497 HARMFLDILKYTYENTTRFEpESQTSATLLR 527
                 6678999**********99854555555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (597 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       537  (0.0299515); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 4103.57
//
Query:       EEA22178.1  [L=397]
Description: fungal specific transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.9e-13   49.0   0.1    6.1e-13   48.4   0.1    1.3  1  Fungal_trans  Fungal specific transcription factor domain
    8.4e-09   35.4  10.9    1.5e-08   34.6  10.9    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
       0.19   12.1   0.0       0.35   11.2   0.0    1.4  1  DarA_C        Defence against restriction A C-terminal


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.4   0.1     1e-16   6.1e-13       2     205 ..     119     314 ..     118     347 .. 0.87

  Alignments for each domain:
  == domain 1  score: 48.4 bits;  conditional E-value: 1e-16
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLl 98 
                   ++ffs +h ++pi+ k  f+++     ++ ++ + +l lla ++  ++ ++se+  sn+ l +           a+ + he  +  + s+++lq+ l
    EEA22178.1 119 KTFFSTIHLWLPIIFKKGFFVSM---LNPWTQRQTELSLLALCMKLCNTAPSEDDGSNNFLYR----------TAKRFHHEVVTAGVLSTHVLQAGL 202
                   78********************9...6677777777777888888888888888888788877..........677788999999************ PP

  Fungal_trans  99 llelyektssdralherhhgvavrlarslgLhrnpsyvgkks......lwklweeeaesrrRlwwaaFylDktialklGrpp.llddsqinlpLPcd 188
                   l++lye++    +++++++g   r    lg ++n +  +  +      ++++w e  e+ rR+wwa+  +D+++ l     p    d   ++ LP d
    EEA22178.1 203 LIALYEMGHAMYPAAYLTVGACSRYGLALGIQQNCYPTSAADdglemrGQRSWNE-VEENRRVWWAVLTFDRFLNLNNPARPlSTEDPTFDTYLPVD 298
                   *************************************99888*****98889988.9999**************9998888877999999999**99 PP

  Fungal_trans 189 dddlwesddaseetlve 205
                   d   w+  +a +++ v 
    EEA22178.1 299 DT-SWNDCTAKASDSVK 314
                   99.88888777777776 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.6  10.9   2.6e-12   1.5e-08       1      35 [.      10      43 ..      10      48 .. 0.93

  Alignments for each domain:
  == domain 1  score: 34.6 bits;  conditional E-value: 2.6e-12
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCT CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfyse 35
                haC +Cr+ K++Cd+k P+C  C+k+ ++C  y+ 
  EEA22178.1 10 HACLPCRRSKRRCDRKLPSCDLCIKKDTDCN-YPG 43
                8*****************************9.875 PP

>> DarA_C  Defence against restriction A C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   5.8e-05      0.35       6      55 ..     227     275 ..     225     279 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 5.8e-05
      DarA_C   6 YyltqrPvdiGtyPkgkdnglleienfdarteveedsrgawGiveYerpL 55 
                 Y+l +  +++++yP++  +  le++   +  evee++r  w +++++r L
  EEA22178.1 227 YGL-ALGIQQNCYPTSAADDGLEMRGQRSWNEVEENRRVWWAVLTFDRFL 275
                 664.67899**************************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       471  (0.0262703); expected 358.6 (0.02)
Passed bias filter:                      326  (0.0181828); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.24s 00:00:00.72 Elapsed: 00:00:00.39
# Mc/sec: 3038.51
//
Query:       EEA22179.1  [L=251]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.2e-26   92.5   0.0    2.8e-26   92.2   0.0    1.1  1  adh_short       short chain dehydrogenase
    6.2e-22   78.3   0.0    7.2e-22   78.1   0.0    1.0  1  adh_short_C2    Enoyl-(Acyl carrier protein) reductase
    1.2e-06   28.6   0.0    1.5e-06   28.2   0.0    1.3  1  KR              KR domain
     0.0014   18.5   0.0     0.0021   18.0   0.0    1.3  1  NAD_binding_10  NAD(P)H-binding


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.2   0.0   6.3e-30   2.8e-26       4     193 ..       5     206 ..       3     208 .. 0.91

  Alignments for each domain:
  == domain 1  score: 92.2 bits;  conditional E-value: 6.3e-30
                 EEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT...TSEEEEEE-TTTSHHHHHHHHHHHHHHH.SSESEEEE---S..S--SSGGGC CS
   adh_short   4 lvtGassGIGraiakelakeGakvvvvdrseekleevakelkee...gakalaiqvDvtdreevealvekavkkl.gkldvLvnNAGi..tgsgpfsel 96 
                 l+tG s+G+G+ +a el+k+  ++v++  ++ +    +++lk e   +++++ + +Dv++ e+++a+v++ +  l  +ld L  NAG+  + +++f+e+
  EEA22179.1   5 LITGTSRGLGLGFAAELLKDSKNLVIATARNTASSSGLQKLKVEypqNDRLILLDLDVSNVESIRAAVKTLEPLLpNGLDNLLSNAGVsySSMKTFEEI 103
                 8*********************9999555556666888888877777899**********************999999**********9999******* PP

                 SHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-T.....TBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBS.SHHHHH CS
   adh_short  97 seeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpva.....gvaaYsAsKaavagltrslakelaptgirvnavaPGlvd.Tdmake 189
                 + +e+ + +   +t++f+l r++lp + k++  r  +v+S+ g  ++a      + aYs + aa+++l+r+++  l+++gi+  +++PG +  T+m  e
  EEA22179.1 104 DIAEFTSEVIFTVTAPFNLLREFLPLIRKSETKRALFVTSILGSIELApnlpnLMNAYSVARAALNMLVRKWSVILKQEGITAAVIHPGWIGeTEMGDE 202
                 **************************99***************8765422233789***********************************99****99 PP

                 HCTH CS
   adh_short 190 lrek 193
                 ++e+
  EEA22179.1 203 ISEW 206
                 9987 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.1   0.0   1.6e-25   7.2e-22       1     216 [.       8     231 ..       8     246 .. 0.82

  Alignments for each domain:
  == domain 1  score: 78.1 bits;  conditional E-value: 1.6e-25
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGH.HHHHHHHHHHTTSE...E.EE--TTSHHHHHHHHHHHHHHH.SSEEEEEE-----EGCSS-GGGH- CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneea.kkrveelaeelgae...v.lecDVtdeeqvealveevvekf.gklDilvnnagiapklkgpflets 91 
                   G  +g+G + A +l +   ++v++ +++ a  + +++l+ e++++   + l +DV++ e+++a+v++++  + ++lD l+ nag++ +  + f+e++
    EEA22179.1   8 GTSRGLGLGFAAELLKDSKNLVIATARNTAsSSGLQKLKVEYPQNdrlIlLDLDVSNVESIRAAVKTLEPLLpNGLDNLLSNAGVSYSSMKTFEEID 104
                   6789*******999999999998888888879**********96657548**********************9***************9******** PP

                   HHHHHHHHHHHTHHHHHHHHHHHHHCTSC...CEEEEEEEGGGTSBSTTTT....HHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--B.HCTGGG CS
  adh_short_C2  92 reefdraldvnlyslfllakaalplmkeg...gsivnlssvgaervvpnyn....aygaaKaalealtrylAvelgpkgiRvNavspgpi.kTlaas 180
                    +ef   +   +++ f+l++++lpl++++    ++  +s +g+    pn      ay++a+aal+ l+r + v l ++gi+  +++pg+i +T++ +
    EEA22179.1 105 IAEFTSEVIFTVTAPFNLLREFLPLIRKSetkRALFVTSILGSIELAPNLPnlmnAYSVARAALNMLVRKWSVILKQEGITAAVIHPGWIgETEMGD 201
                   ************************8887778445555555677777877544446***********************************5566666 PP

                   GSTTHHHHHHHHHHHSTTSS-B-HHHHHHHHHHHCS CS
  adh_short_C2 181 gikgfdelleelearaplgrlgtpeevaeaalfLas 216
                   +i+      e++++  p  ++ ++e+ a+ ++ ++ 
    EEA22179.1 202 EIS------EWVAKYNPALENLSTEKAAADCMKILN 231
                   655......666666666666666666666555555 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.2   0.0   3.4e-10   1.5e-06       2     121 ..       3     124 ..       2     193 .. 0.75

  Alignments for each domain:
  == domain 1  score: 28.2 bits;  conditional E-value: 3.4e-10
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHS.S---EEEE------..---T CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaee.ppikGvihaAgvlr..dkll 97 
                 +ylitG   gLGl +a  l+++ ++ ++ ++R+  a+++  ++++    ++ +  ++++Dvs+ ++++a++++++    + +   +  Agv+    k++
  EEA22179.1   3 SYLITGTSRGLGLGFAAELLKDSKNLVIATARNT-ASSSGLQKLKVEYPQNDRLILLDLDVSNVESIRAAVKTLEPLLpNGLDNLLSNAGVSYssMKTF 100
                 6********************************4.455555566666667889**********************999899999999999975225678 PP

                 TT--HHHHHHHHTTTTHHHHHHHH CS
          KR  98 eemtaedleqvlapKvkGawnLhe 121
                 ee + +++++ +   v++  nL +
  EEA22179.1 101 EEIDIAEFTSEVIFTVTAPFNLLR 124
                 888888887766666666665544 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   4.7e-07    0.0021       3     150 ..      10     198 ..       8     232 .. 0.72

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 4.7e-07
                     TSHHHHHHHHHHHHC-T-EEEEEETTHHHCH.......HHHCTTTCEEEE--TT-CCHHHHHHT........T-SEEEES---TCC....HHHH. CS
  NAD_binding_10   3 tGkvGrllvkellargghevtalvRnpekla.......eleaeeglevvegdvtdvedlaealk........gadaVvsalggggk....deeg. 77 
                     + + G   ++ell++++  v a +Rn+++ +       e++++++l ++++dv++ve++++a+k        g d  +s++g + +         
      EEA22179.1  10 SRGLGLGFAAELLKDSKNLVIATARNTASSSglqklkvEYPQNDRLILLDLDVSNVESIRAAVKtlepllpnGLDNLLSNAGVSYSsmktF--Ee 102
                     56678888999****98889******887765555555566999********************999999999999999997776644442..04 PP

                     ....................HHHHHHHHHHCT--EEEEEEETTTTSGCGCHHHHHHH..HCCHHHHHH.HHHHHHHHHHSSSEEEEEEE-CEE-S CS
  NAD_binding_10  78 ....................aknivdaakeagvkRfvlvsaigvgdevpgefgewnk..ellkaylaa.kraaeellrasgldwTivrpggLtde 149
                                          +  +   +++++kR ++v++i    e + +++++ +  ++ +a+l    r+   +l++ g++  +++pg++ + 
      EEA22179.1 103 idiaeftseviftvtapfnlLREFLPLIRKSETKRALFVTSILGSIELAPNLPNLMNaySVARAALNMlVRKWSVILKQEGITAAVIHPGWIGET 197
                     467777777889888888888888999************99866655555555543311233333333133333446779999999999998766 PP

                     T CS
  NAD_binding_10 150 p 150
                     +
      EEA22179.1 198 E 198
                     5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (251 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       509  (0.0283898); expected 358.6 (0.02)
Passed bias filter:                      484  (0.0269954); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 1637.94
//
Query:       EEA22180.1  [L=174]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.9e-52  176.7   0.0    4.5e-52  176.5   0.0    1.0  1  DUF1768   Domain of unknown function (DUF1768)


Domain annotation for each model (and alignments):
>> DUF1768  Domain of unknown function (DUF1768)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  176.5   0.0   2.5e-56   4.5e-52       1     160 [.      14     172 ..      14     173 .. 0.93

  Alignments for each domain:
  == domain 1  score: 176.5 bits;  conditional E-value: 2.5e-56
     DUF1768   1 fFwkeeeeygflsnwypspftvdgeehkvelealtyntaehymmaqKallfedtev..aeeil..ak.spkeakalgrkvrnfdeedWeeekeevvreg 94 
                 +Fwk+e +ygfl +w+ps+f++++++     e+ ty +ae+ymm++Kallf+  e   + +i+   k  p+ +++lgr++ nf+ee W+++++e+v eg
  EEA22180.1  14 YFWKPEGDYGFLGQWWPSSFSWKTDD-----EEYTYASAEQYMMHRKALLFAGPEDpiTLQIQtgWKlRPSVIRDLGRQIPNFSEEAWQQNRYEIVLEG 107
                 8***988*************999988.....899******************5554337777754337******************************* PP

     DUF1768  95 nlaKfsqneelrelLlatgdrelveasprDriWGiGlkadeaaeerekwkGkNlLGkalmevReel 160
                 n+ Kfsqneel+e+Ll+tg relveasprDriWGiG++a++a ++r++w G NlLGk+lme Re+l
  EEA22180.1 108 NYLKFSQNEELKEKLLETGARELVEASPRDRIWGIGFGARHAGANRREW-GLNLLGKVLMETRERL 172
                 ****************************************9999*****.**************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (174 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       326  (0.0181828); expected 358.6 (0.02)
Passed bias filter:                      281  (0.0156729); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.45
# Mc/sec: 1172.14
//
Query:       EEA22181.1  [L=284]
Description: aldo-keto reductase (AKR), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.8e-38  131.8   0.0    8.8e-36  123.6   0.0    2.0  1  Aldo_ket_red  Aldo/keto reductase family
  ------ inclusion threshold ------
       0.12   12.4   0.0        2.2    8.4   0.0    2.4  2  Cas9_Topo     Topo homolgy domain in CRISPR-associated endonu


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.6   0.0   9.8e-40   8.8e-36      17     289 ..      31     273 ..      22     275 .. 0.92

  Alignments for each domain:
  == domain 1  score: 123.6 bits;  conditional E-value: 9.8e-40
                   HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH-TTTGGG-EEEEEE--SSSTTSSSS-HHHHHHHHHHHHHHHT-.S-EEEEEE-S--T CS
  Aldo_ket_red  17 keealellrraleaGinffDtAevYgkgqseellGealkksrkkreeviiatKvdlrdaeiksglskeniresleeslkrLgt.dyvDllllHrpdp 112
                   +++   +++ al+aG++++D+A +Y   q+e   +  + ks+ +reev+ +tKv      +++ +s e   es+++sl + g  +y+Dl+llH p+ 
    EEA22181.1  31 PSDTSIAIQEALKAGYRHIDSAAFY---QNEAACADGIIKSGIPREEVFFTTKV------PPQAISYEGAKESVKRSLGKAGQlKYIDLVLLHAPFG 118
                   5555567899***************...*****88877777*************......******************888766************* PP

                   TS-.HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHH...........HHTTT--EEEEE-B-BTT-HHHHTTHHHHHHHTT-EEEEBSTTGGGTTG CS
  Aldo_ket_red 113 slpsieevldaleelvkeGkiraiGvSnfsveqleka...........kkkkkvkivavqveynllreleeegllelckkkgvpliaysplggGllt 198
                     + ++ +++al+e v++G +r+iGvSn+ v++l+++            k k+  ++++q+e +++  l+ + +++ c+k gv + a+ pl++    
    EEA22181.1 119 GKEGRLGAWKALVEAVEAGTVRSIGVSNYGVQHLDELekyiketdaklGKGKGGVLSVNQIELHPW--LQRKDIIDWCQKRGVLVQAWAPLAQA--- 210
                   ******************************************9998766666667***********..************************43... PP

                   TTTSS---SSSCCC-------TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTSTT-SEEEE--SSHHHHHHHHGGGG----HHHHHHH CS
  Aldo_ket_red 199 gkyqseedkedkeprkdlkrdertsknldaaeelselakehgvslaqlalryalsqpavgivipgasnieqlednldalelklseeevael 289
                                             n+  ++ l++++k  g++ aq+ lr+ l  +++  ++p++ +++++ +n + ++++ls++e+a +
    EEA22181.1 211 --------------------------NRWNDPSLKDIVKRTGKTEAQILLRWSL--QKGFNPLPKSVTPSRIVENTKIFDFELSDSELAVM 273
                   ..........................2345789*********************..99****************************99866 PP

>> Cas9_Topo  Topo homolgy domain in CRISPR-associated endonuclease Cas9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   0.0   0.00024       2.2      32      66 ..      73     108 ..      70     112 .. 0.84
   2 ?    0.8   0.0     0.059   5.3e+02      52      67 ..     128     143 ..     123     144 .. 0.87

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00024
   Cas9_Topo  32 nedLfsvelkpqsismRtaekklrkAi.aeGkaeyl 66 
                 +e  f+++++pq+is   a++++++ + + G+ +y+
  EEA22181.1  73 EEVFFTTKVPPQAISYEGAKESVKRSLgKAGQLKYI 108
                 56789********************99345777776 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.059
   Cas9_Topo  52 kklrkAiaeGkaeylG 67 
                 k l++A++ G+++ +G
  EEA22181.1 128 KALVEAVEAGTVRSIG 143
                 789*********9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (284 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       363  (0.0202465); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.23s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2021.28
//
Query:       EEA22182.1  [L=264]
Description: DnaJ domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.9e-19   67.6   2.8    1.6e-18   67.0   1.2    1.9  2  HSCB_C    HSCB C-terminal oligomerisation domain
    8.9e-07   28.9   0.0    1.8e-06   28.0   0.0    1.4  1  DnaJ      DnaJ domain


Domain annotation for each model (and alignments):
>> HSCB_C  HSCB C-terminal oligomerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0      0.19   1.7e+03      38      66 ..     128     151 ..     122     158 .. 0.46
   2 !   67.0   1.2   1.8e-22   1.6e-18       2      75 ..     174     250 ..     173     251 .. 0.90

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.19
                 HHHHHHHHHHHHHHTT-HHHHHHHHHHHH CS
      HSCB_C  38 rieeleaeleeafekkdleaaadllrrlr 66 
                 r e+l +++++      + ++ d l+r +
  EEA22182.1 128 RAEALSSRIND-----AYRTLSDPLSRAQ 151
                 33333333333.....3344444444444 PP

  == domain 2  score: 67.0 bits;  conditional E-value: 1.8e-22
                 -HHHHHHHHHHHHHHHCG....GGSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHHHHH CS
      HSCB_C   2 dpefLmevMelrEeleea....eeaadkeeleelkaeveerieeleaeleeafekkdleaaadllrrlrYlekikeei 75 
                 d e Lme+M+++E++ee+     ++  ++++++l+ae+  rie+++a+l++af++ d+e+a+++++rlr+++++++ +
  EEA22182.1 174 DHETLMEIMDVQETVEELssapVAE-AEATINRLRAENAGRIEDSVAKLQKAFAEGDIETAQMETVRLRFWYSLRDGL 250
                 89****************6665333.33*************************888******************9987 PP

>> DnaJ  DnaJ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.0   0.0     2e-10   1.8e-06      15      62 ..     102     152 ..      96     152 .. 0.86

  Alignments for each domain:
  == domain 1  score: 28.0 bits;  conditional E-value: 2e-10
                 HHHHHHHHHHHHHHSTTTSCCHH...HHHHHHHHHHHHHHHHTSHHHHHHH CS
        DnaJ  15 deIkkaYrklalkyHPDknpkdp...eaeekFkeineAyevLsdpekRkqY 62 
                 + +++++ +l   +HPDk p+ p   +ae    +in+Ay +Lsdp +R+qY
  EEA22182.1 102 AALRREFLQLQGAVHPDKYPQGPekqRAEALSSRINDAYRTLSDPLSRAQY 152
                 56899999*********9955554448888999*****************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (264 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       703  (0.0392102); expected 358.6 (0.02)
Passed bias filter:                      567  (0.0316247); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.41u 0.24s 00:00:00.64 Elapsed: 00:00:00.36
# Mc/sec: 2175.73
//
Query:       EEA22183.1  [L=526]
Description: pre-mRNA splicing factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.8e-36  123.5  21.1    1.1e-08   35.5   2.1    7.8  7  WD40         WD domain, G-beta repeat
    1.1e-14   53.7   5.3    1.9e-14   52.9   5.3    1.5  1  PRP4         pre-mRNA processing factor 4 (PRP4) like
    2.7e-13   50.0   0.3      0.012   15.9   0.0    5.7  6  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
     0.0017   17.4   0.0         11    4.8   0.0    4.3  5  Ge1_WD40     WD40 region of Ge1, enhancer of mRNA-decapping p
     0.0057   16.6   0.0       0.71    9.7   0.0    3.2  2  eIF2A        Eukaryotic translation initiation factor eIF2A
  ------ inclusion threshold ------
      0.017   14.4   0.0       0.21   10.9   0.0    2.7  4  WD40_like    WD40-like domain
       0.75    8.4   3.6         11    4.5   0.0    2.9  3  Nup160       Nucleoporin Nup120/160


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0      0.39     1e+03      17      30 ..     208     222 ..     193     228 .. 0.76
   2 !   15.9   0.1   6.9e-06     0.018       6      38 .]     239     283 ..     234     283 .. 0.87
   3 !   33.3   0.0   2.2e-11   5.6e-08       2      38 .]     288     325 ..     287     325 .. 0.94
   4 !   22.6   0.0   5.2e-08   0.00013       8      38 .]     336     367 ..     329     367 .. 0.92
   5 !   18.4   0.8   1.2e-06    0.0029       2      38 .]     372     409 ..     371     409 .. 0.92
   6 ?    3.2   0.1      0.07   1.8e+02       3      24 ..     415     437 ..     413     482 .. 0.49
   7 !   35.5   2.1   4.4e-12   1.1e-08       2      37 ..     487     523 ..     486     523 .. 0.92

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.39
                 E.EETTSSEEEEEET CS
        WD40  17 a.fspdgawlasGsd 30 
                   f pdg  +a+G +
  EEA22183.1 208 TrFAPDGETIATGNW 222
                 2489*******9965 PP

  == domain 2  score: 15.9 bits;  conditional E-value: 6.9e-06
                 EEESSSS.EEEEEEETTSSE...........EEEEETTSEEEEEE CS
        WD40   6 tltGHss.vtslafspdgaw...........lasGsdDgtvriWd 38 
                 + +GHs+ vt+l++ p  ++           lasG+  g++ +W+
  EEA22183.1 239 SVKGHSDrVTGLSWFPGATLstsnvsesslnLASGGGEGNINLWS 283
                 679**556*****999999999999999999999987*******5 PP

  == domain 3  score: 33.3 bits;  conditional E-value: 2.2e-11
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 ++l tl+GH   ++ + f+p+g++las+s+D t r+Wd
  EEA22183.1 288 EPLATLSGHtERICRVEFHPSGKYLASASYDTTWRLWD 325
                 6899*****666*************************9 PP

  == domain 4  score: 22.6 bits;  conditional E-value: 5.2e-08
                 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +GH + v++++f++dg++lasG+ D   riWd
  EEA22183.1 336 EGHsKEVYAVSFNSDGSLLASGGLDSYGRIWD 367
                 5**888*************************9 PP

  == domain 5  score: 18.4 bits;  conditional E-value: 1.2e-06
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +++ +l GH   ++++++  dg  +++Gs Dg v+ Wd
  EEA22183.1 372 RTVMVLQGHiREIYGVDWGVDGYRVLTGSGDGWVKCWD 409
                 67889****888****9999********99*******9 PP

  == domain 6  score: 3.2 bits;  conditional E-value: 0.07
                 EEEEEESSSS.EEEEEEETTSSE CS
        WD40   3 clrtltGHss.vtslafspdgaw 24 
                 c+ ++ +H+s v+++++ + g+ 
  EEA22183.1 415 CTASIGAHKSvVSDVRWYKGGDS 437
                 67777788774588854444433 PP

  == domain 7  score: 35.5 bits;  conditional E-value: 4.4e-12
                 EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   2 qclrtltGHss.vtslafspdgawlasGsdDgtvriW 37 
                 +++++l+GHs+ v s++ spd +w+as+s D+tv++W
  EEA22183.1 487 SLVKSLSGHSDkVLSVDISPDAKWIASSSHDRTVKLW 523
                 7899*****666**************9999******* PP

>> PRP4  pre-mRNA processing factor 4 (PRP4) like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.9   5.3   7.4e-18   1.9e-14       1      28 [.      70      97 ..      70      98 .. 0.97

  Alignments for each domain:
  == domain 1  score: 52.9 bits;  conditional E-value: 7.4e-18
        PRP4  1 VrrrLRelGEPitLFGEthadRreRLrk 28
                Vr rLRelGEPitLFGE++adRr+RLr+
  EEA22183.1 70 VRLRLRELGEPITLFGEGPADRRDRLRE 97
                99*************************8 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   0.0         7   1.8e+04      53      68 ..      61      76 ..      55      83 .. 0.72
   2 !   10.5   0.0   0.00023      0.59      34      89 ..     198     252 ..     177     254 .. 0.88
   3 !   11.7   0.0   9.8e-05      0.25      35      71 ..     294     330 ..     270     335 .. 0.83
   4 !   15.9   0.0   4.6e-06     0.012      34      91 ..     335     391 ..     330     392 .. 0.91
   5 !    6.1   0.2    0.0052        13      39      90 ..     382     432 ..     377     434 .. 0.91
   6 ?    1.9   0.0      0.11   2.8e+02      26      65 ..     486     523 ..     463     526 .] 0.66

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 7
  ANAPC4_WD40 53 Lavaysdgevrlldae 68
                 + v ++d++vrl   e
   EEA22183.1 61 IIVPTDDNRVRLRLRE 76
                 6778889999886555 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00023
  ANAPC4_WD40  34 edkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                  + + d+ v+  ++ pdg+ +a +   g ++ll++ + +   s++ +s+ +vt l+W
   EEA22183.1 198 QIAADRPVSITRFAPDGETIATGNWAGGIKLLSVPNLEEKFSVKGHSD-RVTGLSW 252
                  567789999999********************************9999.6****99 PP

  == domain 3  score: 11.7 bits;  conditional E-value: 9.8e-05
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdgevrlldaesgk 71 
                  +++ +++  ++++p+gk La a  d++ rl d+e+++
   EEA22183.1 294 SGHTERICRVEFHPSGKYLASASYDTTWRLWDVETTT 330
                  67889999**************************976 PP

  == domain 4  score: 15.9 bits;  conditional E-value: 4.6e-06
  ANAPC4_WD40  34 edkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgWge 91 
                  ++++++ev +++++ dg+lLa +  d+  r+ d  +g++v  l+ +  + +  ++Wg+
   EEA22183.1 335 QEGHSKEVYAVSFNSDGSLLASGGLDSYGRIWDLRTGRTVMVLQGHIRE-IYGVDWGV 391
                  567899*************************************999885.99999986 PP

  == domain 5  score: 6.1 bits;  conditional E-value: 0.0052
  ANAPC4_WD40  39 sevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgWg 90 
                  +e+ ++ W  dg     +  dg v+  d  + ++  s+ ++++  v+ + W 
   EEA22183.1 382 REIYGVDWGVDGYRVLTGSGDGWVKCWDLRKVDCTASIGAHKS-VVSDVRWY 432
                  688999*********************************9999.69999995 PP

  == domain 6  score: 1.9 bits;  conditional E-value: 0.11
  ANAPC4_WD40  26 gqrvwtleedkedsevrsLaWkpdgklLavaysdgevrll 65 
                  +  v +l  ++++ +v s+  +pd k +a + +d +v+l 
   EEA22183.1 486 WSLVKSL--SGHSDKVLSVDISPDAKWIASSSHDRTVKLW 523
                  3344444..5667778888888888888888888887775 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0     0.029        73     184     216 ..     199     231 ..     149     244 .. 0.83
   2 ?    2.9   0.0     0.017        43     177     217 ..     286     327 ..     275     332 .. 0.83
   3 ?    0.1   0.0      0.12   3.1e+02     185     215 ..     336     367 ..     326     373 .. 0.80
   4 ?   -0.3   0.0      0.16   4.1e+02     184     219 ..     377     413 ..     368     423 .. 0.78
   5 !    4.8   0.0    0.0045        11     184     216 ..     492     525 ..     470     526 .] 0.84

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.029
    Ge1_WD40 184 ieehsliveaafspdGtalatasedGevkffqv 216
                 i  +  ++ + f+pdG ++at    G +k+  v
  EEA22183.1 199 IAADRPVSITRFAPDGETIATGNWAGGIKLLSV 231
                 45555677889***************9998776 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.017
    Ge1_WD40 177 ieegllkieehs.liveaafspdGtalatasedGevkffqvy 217
                 ++e l  ++ h+  i    f p G  la as d + +++ v 
  EEA22183.1 286 KKEPLATLSGHTeRICRVEFHPSGKYLASASYDTTWRLWDVE 327
                 5666677888876899**********************9986 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.12
    Ge1_WD40 185 eehs.liveaafspdGtalatasedGevkffq 215
                 e hs ++   +f +dG  la    d + + + 
  EEA22183.1 336 EGHSkEVYAVSFNSDGSLLASGGLDSYGRIWD 367
                 4566589999************9999888876 PP

  == domain 4  score: -0.3 bits;  conditional E-value: 0.16
    Ge1_WD40 184 ieehs.liveaafspdGtalatasedGevkffqvyle 219
                 ++ h  +i    +  dG  + t s dG vk + +  +
  EEA22183.1 377 LQGHIrEIYGVDWGVDGYRVLTGSGDGWVKCWDLRKV 413
                 555544777788889***************9987655 PP

  == domain 5  score: 4.8 bits;  conditional E-value: 0.0045
    Ge1_WD40 184 ieehs.liveaafspdGtalatasedGevkffqv 216
                 ++ hs ++ +  +spd   +a +s+d +vk++ +
  EEA22183.1 492 LSGHSdKVLSVDISPDAKWIASSSHDRTVKLWGI 525
                 66787789999********************976 PP

>> eIF2A  Eukaryotic translation initiation factor eIF2A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   0.0   0.00028      0.71     122     172 ..     274     329 ..     158     343 .. 0.67
   2 ?    3.1   0.0     0.029        75     101     162 ..     340     400 ..     323     419 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00028
                 SSS-EEEEEETTTTEEEEEEE..-TT--EEEE-TTSSEEEEEE..-TTT-.SSS-E CS
       eIF2A 122 nlaGeleiwdvkkkkkiakae..aanatlvewspdgryvlTat..taprl.rvdng 172
                   +G++++w  +kk+ +a++    +    ve++p+g+y++ a+  t++rl  v+++
  EEA22183.1 274 GGEGNINLWSLDKKEPLATLSghTERICRVEFHPSGKYLASASydTTWRLwDVETT 329
                 3469***********999986215667789**********9975567776245555 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.029
                 ES--EEEE-TTSSEEEEE-TTSSS-EEEEEETT..TTEEEEEEE-TT--EEEE-TTSSEEEEEE CS
       eIF2A 101 qkrNtiffspkgklvllaGfgnlaGeleiwdvk..kkkkiakaeaanatlvewspdgryvlTat 162
                 ++  ++ f++ g l++ +G+ +  G+  iwd    ++  + + +  +   v+w  dg  vlT +
  EEA22183.1 340 KEVYAVSFNSDGSLLASGGLDSY-GR--IWDLRtgRTVMVLQGHIREIYGVDWGVDGYRVLTGS 400
                 5566899*************999.86..588774355555666777888999999999999965 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       0.4     1e+03      13      51 ..     268     306 ..     259     334 .. 0.55
   2 ?   10.9   0.0   8.1e-05      0.21       2      48 ..     341     387 ..     340     417 .. 0.79
   3 ?   -1.0   0.0      0.33   8.5e+02       2      37 ..     383     418 ..     382     429 .. 0.82
   4 ?   -2.9   0.0       1.2   3.2e+03       3      26 ..     499     522 ..     497     525 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.4
   WD40_like  13 slilyGgkddkctvlkleslesvsivesfedSvifvkll 51 
                   ++ Gg + ++ + +l+ +e    + + ++ +  v++ 
  EEA22183.1 268 LNLASGGGEGNINLWSLDKKEPLATLSGHTERICRVEFH 306
                 444555555555555555555555555555554444443 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 8.1e-05
   WD40_like   2 eiYsidiskkgslilyGgkddkctvlkleslesvsivesfedSvifv 48 
                 e+Y++ ++ +gsl++ Gg d   ++ +l+++ +v ++++    +  v
  EEA22183.1 341 EVYAVSFNSDGSLLASGGLDSYGRIWDLRTGRTVMVLQGHIREIYGV 387
                 9*********************************9988766555555 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 0.33
   WD40_like   2 eiYsidiskkgslilyGgkddkctvlkleslesvsi 37 
                 eiY +d   +g  +l G+ d  ++  +l+  +   +
  EEA22183.1 383 EIYGVDWGVDGYRVLTGSGDGWVKCWDLRKVDCTAS 418
                 9*****************999988888877665555 PP

  == domain 4  score: -2.9 bits;  conditional E-value: 1.2
   WD40_like   3 iYsidiskkgslilyGgkddkctv 26 
                 + s+dis++++ i+  ++d ++++
  EEA22183.1 499 VLSVDISPDAKWIASSSHDRTVKL 522
                 789***********9999988876 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.2      0.01        26     231     254 ..     310     333 ..     302     355 .. 0.79
   2 ?   -2.1   0.0      0.44   1.1e+03     243     255 ..     364     376 ..     345     379 .. 0.83
   3 ?    4.5   0.0    0.0042        11     235     285 ..     398     445 ..     394     471 .. 0.78

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.01
                 TEEEEEETT-EEEEEETTTTEEEE CS
      Nup160 231 tylfalsrdgkLrvWnlltgkcla 254
                 +yl+++s d + r+W+++t + l 
  EEA22183.1 310 KYLASASYDTTWRLWDVETTTELL 333
                 699***************987665 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.44
                 EEEETTTTEEEEE CS
      Nup160 243 rvWnlltgkclat 255
                 r+W+l+tg+++++
  EEA22183.1 364 RIWDLRTGRTVMV 376
                 9*******99875 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.0042
                 EEETT-EEEEEETTTTEEEEEEE--.-SSSTTS--SSEESEEESSSSEEEE CS
      Nup160 235 alsrdgkLrvWnlltgkclatidllrdeeaqdessskstldpaesslirvs 285
                 + s dg+++ W+l+   c+a+i       + ++ +++ +++++ +s+++  
  EEA22183.1 398 TGSGDGWVKCWDLRKVDCTASIGAH---KSVVSDVRWYKGGDSAQSYLPTT 445
                 5578*****************8888...36666666667777777776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (526 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       505  (0.0281667); expected 358.6 (0.02)
Passed bias filter:                      408  (0.0227564); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.66u 0.33s 00:00:00.99 Elapsed: 00:00:00.50
# Mc/sec: 3154.78
//
Query:       EEA22184.1  [L=538]
Description: PWWP domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-16   60.8   8.4    1.9e-16   60.2   3.1    3.5  2  PWWP      PWWP domain


Domain annotation for each model (and alignments):
>> PWWP  PWWP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.2   3.1   1.1e-20   1.9e-16       2      93 ..     110     217 ..     109     306 .. 0.95
   2 ?    0.3   0.1     0.053   9.5e+02      21      55 ..     348     383 ..     343     409 .. 0.60

  Alignments for each domain:
  == domain 1  score: 60.2 bits;  conditional E-value: 1.1e-20
                 STTEEEEEEESSSEEEEEEEEECCCCCCCCHCT---SSS....................EEEEEETTTTEEEEE-GGGEEE-SHHHHHHHHHTTSS-HH CS
        PWWP   2 qpgdlvwakvkgypwWPavvidpeevpekvlkkkekske....................lylVkFfgdkeyawvkekdlkpfteedeeeylkkkkkkks 80 
                 +pg+ ++a++k++p+WPa+++d+e++p + l++++ +++                    +++++F+ ++e+aw++++dl+p+++e++++  +k+k+k  
  EEA22184.1 110 APGEYYLARLKSFPPWPAIICDEEMLPLSLLNTRPVTTKqadgtykeayadggrraydrTFPIMFLETNEFAWIPNTDLTPLDPEQCKDVSEKGKQK-- 206
                 69******************************99999889*************************************************99999997.. PP

                 HHHHHHHHHHHHH CS
        PWWP  81 kkkfkkAleeaee 93 
                   ++  A++ a e
  EEA22184.1 207 --QLIAAYKVAAE 217
                 ..67777777665 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.053
                 EEECCCCCCCCHCT---SSSEEEEEETTTTEE.EEE CS
        PWWP  21 vidpeevpekvlkkkekskelylVkFfgdkey.awv 55 
                 v++p+e   +++ +++k +++  V F+  k +   +
  EEA22184.1 348 VVPPKEKTPQIDPQEAKANKQKRVLFLRHKLQkGFL 383
                 555655555666666666667889999876665555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (538 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2668  (0.148809); expected 358.6 (0.02)
Passed bias filter:                      652  (0.0363657); expected 358.6 (0.02)
Passed Vit filter:                       132  (0.00736237); expected 17.9 (0.001)
Passed Fwd filter:                        44  (0.00245412); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 1.28u 0.41s 00:00:01.69 Elapsed: 00:00:00.61
# Mc/sec: 2641.29
//
Query:       EEA22185.1  [L=334]
Description: sulfonate biosynthesis enzyme, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.9e-89  297.3   0.0    9.4e-89  297.0   0.0    1.0  1  ComA      (2R)-phospho-3-sulfolactate synthase (ComA)
  ------ inclusion threshold ------
       0.02   15.4   0.0      0.035   14.6   0.0    1.4  1  DUF2542   Protein of unknown function (DUF2542)


Domain annotation for each model (and alignments):
>> ComA  (2R)-phospho-3-sulfolactate synthase (ComA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  297.0   0.0     1e-92   9.4e-89       2     242 ..      68     317 ..      67     318 .. 0.98

  Alignments for each domain:
  == domain 1  score: 297.0 bits;  conditional E-value: 1e-92
                 XXX-SS-SSS-EEEEESS.....--HHHHHHHHHHHGGG-SEEEE-TTGGGGSTCHHHHHHHHHHHCTT-EEEE-HHHHHHHHHTT....-HHHHHHHH CS
        ComA   2 ereekPrktGlTeviDkG.....lglreledlletageyiDglKlgggtsallpeeilrekielahehgvyvstGgtlfEaalaqg....kvdeyleec 91 
                  r++kPr +G+Te+  +G     +g+r++ dllet+g+++DglK++gg+++l+pe+ lre+i+lahe+gvyvstGg ++E++l++      +++yl +c
  EEA22185.1  68 PRPKKPRMKGVTEI--RGpyysvMGKRYFADLLETMGAHVDGLKFAGGSFSLFPEKQLRELIDLAHEYGVYVSTGG-WAEHLLTHAdtetVFEKYLLKC 163
                 79************..************************************************************.********999999******** PP

                 HHCT-SEEEE--SSS---HHHHHHHHHHHCCTTSEEEEEES-SSH........HHHTT..--CCHHHHHHHHHHHHTECEEEE--TTT--SSTTB-TTS CS
        ComA  92 kelgfdviEvsdgtlelpeeeklrliekakkeglkvlpevgkkdg........elese..sdveklieeakrdleaGaekviiEaresGitegvydekg 180
                 k+lgfdv+E+s+g+l++p +++lrli+k++++ l ++pe+g+++g        ele+   sd+ kli+ ++++l+aG+e+++iE++  Gite+v    +
  EEA22185.1 164 KDLGFDVVELSSGFLSFPADDWLRLIDKVHSHKLIAKPELGIQFGaggdtsagELEAIgtSDPGKLINLGQKFLSAGVERLMIESE--GITENV----K 256
                 *********************************************999998886666688**************************..******....* PP

                 -B-HHHHHHHHTTS-GGGEEEE--SHHHHHHHHHHH-TT--EEEEEGGGHHHHHHHHCT-SG CS
        ComA 181 evrtdvvekiierlgleklifEApekkqqewfikefGpnVnLgnvdpsevlaLealRlglrg 242
                 ++rtdvv+ki+++l++e+++fEA+++k+ +w+i+efG +Vn+ +vd+s++++Le+lR+g++g
  EEA22185.1 257 SWRTDVVSKIMKELPMERVMFEAADPKVYNWYIREFGVDVNV-FVDHSQIVQLECLRRGIWG 317
                 ******************************************.******************8 PP

>> DUF2542  Protein of unknown function (DUF2542)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.0     4e-06     0.035      13      60 ..     244     291 ..     234     308 .. 0.87

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 4e-06
     DUF2542  13 llvplfclreaykGwraGavdkvvknarepvyvyraedpllyfsylvl 60 
                 l++    + e  k wr+  v k++k+ +    ++ a+dp  y  y+  
  EEA22185.1 244 LMIESEGITENVKSWRTDVVSKIMKELPMERVMFEAADPKVYNWYIRE 291
                 56666678899******************99***********999865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (334 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      467  (0.0260472); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2308.82
//
Query:       EEA22186.1  [L=522]
Description: cytochrome P450 alkane hydroxylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-61  208.4   0.0    2.4e-61  207.9   0.0    1.0  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  207.9   0.0   1.3e-65   2.4e-61      10     446 ..      58     502 ..      52     517 .. 0.87

  Alignments for each domain:
  == domain 1  score: 207.9 bits;  conditional E-value: 1.3e-65
                 CHCHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHHHHHHHHHTS CS
        p450  10 vgnllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkklRrfltptlts 108
                 +  +lq++r+++  + ++kl ++ g+++   + ++++ v  +pe +k+ l ++ ++f   +++  +     pf+g g+++ +g+ w   R +l p++  
  EEA22186.1  58 FKTILQYSRQHKALDLINKLIRENGNTYEDVVLGTKALVTAEPENIKAMLATQFNDFGLGMRRQIFG----PFLGDGIFTLDGAGWSHSRAMLRPQFSR 152
                 55789****9999999*************99999999999*************77777665655555....8**************************8 PP

                 HSTTTHHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSH............HHHHHHHHHHHHHHHHCHHHHCCCCC CS
        p450 109 fgklsleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledek............lselvkaveelssllskssvqllllf 195
                   + + + ++ + +++l+ +l    g++  +di+e+++k++ld+ ++ lFg++ ++l +++            ++ + +a+++  + +  ++ +  +l+
  EEA22186.1 153 E-QVADVGMLGSHVDQLISQLP-ADGTP--FDIQEYFFKMTLDTATEFLFGESTNCLLEKSekkssalstiggEEGFANAFNKSQDYV-VERSRAQNLY 246
                 8.55788888888888888885.45777..*************************99999999*********9889999999998877.5555777777 PP

                 HHHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHC.......SCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        p450 196 pllkylptkllrklkeavkklkdlldklieerretldsa.......kksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLy 287
                 +l+     + +r +k ++++++ ++d+ +   ++t  ++       + +r+ flda++ ++         +++ l+ ++l++l+aG dTt+s ls  +y
  EEA22186.1 247 WLV--TSAESRRNCKLVHDVVDYYVDAALARYNHTGGDQekfidsaNPDRYVFLDAMIRET--------RDRRALRDQMLNILLAGRDTTASLLSSSFY 335
                 744..46777777777777777777777777777776667888888999999999999996........4788************************** PP

                 HHHHSHHHHHHHHHHHHHHCCTTT...T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEET..T.......EEE-TT-EEEEEHHHHHT-T CS
        p450 288 eLaknPevqeklreEidevlgdkr...eptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvir..g.......ylipkGtevivnlyalhrdp 374
                 +La++P v ++lreEi ++++ ++   ++t++ l ++ yl+ +++E+LRl p+vp    R +t d++++  g       +++pkG +v+  ++ +hr++
  EEA22186.1 336 YLARHPAVWQRLREEILSIFPPSEpadSITIARLREVRYLKHFLNEVLRLLPPVP-VNGRFATVDTTLPvgGgpdgkspVFVPKGLKVQYQVTVMHRRK 433
                 ********************7666789****************************.999********96442466799********************* PP

                 TTS.SSTTS--GGGGB-TTSCTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGEE CS
        p450 375 evf.pnPeeFdpeRFldekgnskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdpppi 446
                 +++ p++eeF+peR++++ g   r+  ++lPF  GpR+C+G++ A  e +++l++lLq+F++ ++ + ++p +
  EEA22186.1 434 DLWgPDAEEFRPERWEEN-G---RHGWEYLPFNGGPRICLGQQYALTEASYVLVRLLQRFDHVTNAQPEVPSP 502
                 ***************988.5...9**************************************98655444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (522 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       491  (0.0273858); expected 358.6 (0.02)
Passed bias filter:                      481  (0.026828); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3554.43
//
Query:       EEA22187.1  [L=1182]
Description: cytoskeleton assembly control protein Sla1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.9e-35  119.5   0.0    6.9e-35  118.7   0.0    1.4  1  SHD1      SLA1 homology domain 1, SHD1
    1.7e-34  117.1   6.2    5.6e-13   48.3   0.1    4.4  4  SH3_1     SH3 domain
    5.4e-30  103.0   9.6    5.3e-12   45.4   0.5    3.9  4  SH3_9     Variant SH3 domain
    3.1e-22   78.0   0.0    2.1e-07   30.5   0.0    4.5  4  SH3_2     Variant SH3 domain
    2.2e-07   31.2 148.6    0.00052   20.4  38.9    6.4  5  DUF1720   Domain of unknown function (DUF1720)
    0.00019   21.4   0.1      0.064   13.3   0.0    3.3  3  SH3_10    SH3 domain
     0.0025   17.8   0.0      0.005   16.8   0.0    1.4  1  SAM_4     SAM domain (Sterile alpha motif)
  ------ inclusion threshold ------
      0.032   14.7   0.0       0.06   13.8   0.0    1.4  1  SAM_1     SAM domain (Sterile alpha motif)
        0.2   12.0   3.9       0.28   11.5   0.8    2.6  3  SH3_3     Bacterial SH3 domain


Domain annotation for each model (and alignments):
>> SHD1  SLA1 homology domain 1, SHD1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.7   0.0   3.4e-38   6.9e-35       2      67 .]     556     621 ..     555     621 .. 0.98

  Alignments for each domain:
  == domain 1  score: 118.7 bits;  conditional E-value: 3.4e-38
        SHD1   2 kskPdpakvRtWtDrtgsFkVeAeflglkdgkirLhkvnGvkiaVpvekmskeDleyvekvtgksl 67 
                 k+kPd++k+R WtDrtg+F+VeA+flgl+dgki+Lhk+nG+kiaVp++kms+eDleyvekvtg+sl
  EEA22187.1 556 KQKPDTTKIRNWTDRTGTFSVEAQFLGLHDGKIHLHKMNGIKIAVPTAKMSVEDLEYVEKVTGESL 621
                 89*************************************************************985 PP

>> SH3_1  SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.4   0.8     4e-14     8e-11       2      40 ..       9      47 ..       8      59 .. 0.86
   2 !   26.0   0.1   2.5e-09   4.9e-06       1      48 []      72     117 ..      72     117 .. 0.94
   3 !   48.3   0.1   2.8e-16   5.6e-13       3      48 .]     420     466 ..     419     466 .. 0.99
   4 ?    0.8   0.0      0.19   3.7e+02      13      28 ..     702     717 ..     696     720 .. 0.82

  Alignments for each domain:
  == domain 1  score: 41.4 bits;  conditional E-value: 4e-14
                ESSSBEXSSTTBXEBSTTEEEEEEEECSSSEEEEEETTS CS
       SH3_1  2 AlYDYeaeesdELsfkkGDviivleksedgWwkgrlkgt 40
                A YDY+++ ++EL ++++D + +l+k++d+Wwk++ k +
  EEA22187.1  9 AVYDYQPQAEGELEIHENDLLYILDKDDDDWWKAKKKAD 47
                99*********************************9875 PP

  == domain 2  score: 26.0 bits;  conditional E-value: 2.5e-09
                 EESSSBEXSSTTBXEBSTTEEEEEEEECSSSEEEEEETTSTEEEEEEG CS
       SH3_1   1 iAlYDYeaeesdELsfkkGDviivleksedgWwkgrlkgtgkeGliPs 48 
                 +AlYDY+ ++++E+sf ++ ++ v + ++ +W  + + +   +G+ P+
  EEA22187.1  72 KALYDYTRQTDEEISFSEDAELSVYDTTDPDWTLVGSGT--DFGFAPA 117
                 7**********************************9997..5999986 PP

  == domain 3  score: 48.3 bits;  conditional E-value: 2.8e-16
                 SSSBEXSSTTBXEBSTTEEEEEEEECSS.SEEEEEETTSTEEEEEEG CS
       SH3_1   3 lYDYeaeesdELsfkkGDviivleksed.gWwkgrlkgtgkeGliPs 48 
                 lYD++a+ +dE++   GD++ vl++s++ +Ww +r++ +g+eG +Ps
  EEA22187.1 420 LYDFMAQGEDEVTVATGDEVVVLDDSKSdEWWMVRRIKNGREGVVPS 466
                 8*********************************************8 PP

  == domain 4  score: 0.8 bits;  conditional E-value: 0.19
                 BXEBSTTEEEEEEEEC CS
       SH3_1  13 ELsfkkGDviivleks 28 
                  L +k+GD++ v    
  EEA22187.1 702 TLGLKEGDILRVMRYL 717
                 589********98765 PP

>> SH3_9  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.4   0.5   2.7e-15   5.3e-12       1      49 []       9      63 ..       9      63 .. 0.93
   2 !   24.2   0.1   1.1e-08   2.2e-05       1      49 []      73     121 ..      73     121 .. 0.98
   3 !   37.6   0.1   7.1e-13   1.4e-09       2      49 .]     420     470 ..     420     470 .. 0.92
   4 ?   -3.0   0.0       3.5     7e+03      13      24 ..     703     714 ..     702     715 .. 0.83

  Alignments for each domain:
  == domain 1  score: 45.4 bits;  conditional E-value: 2.7e-15
       SH3_9  1 AlypyepreddeLsLqrGDvitvieesedgWlegs......ltGrtGlvPanyve 49
                A+y+y+p+ + eL++ ++D ++++++++d+W+ ++       ++  GlvP nyv+
  EEA22187.1  9 AVYDYQPQAEGELEIHENDLLYILDKDDDDWWKAKkkadpeDDEPVGLVPNNYVQ 63
                89********************************9777654499**********7 PP

  == domain 2  score: 24.2 bits;  conditional E-value: 1.1e-08
       SH3_9   1 AlypyepreddeLsLqrGDvitvieesedgWlegsltGrtGlvPanyve 49 
                 Aly+y+ + d+e+s++++  + v + ++++W ++  +   G+ Pany++
  EEA22187.1  73 ALYDYTRQTDEEISFSEDAELSVYDTTDPDWTLVGSGTDFGFAPANYIQ 121
                 8*****99999************************************97 PP

  == domain 3  score: 37.6 bits;  conditional E-value: 7.1e-13
       SH3_9   2 lypyepreddeLsLqrGDvitviee.sedgWlegsl..tGrtGlvPanyve 49 
                 ly++ ++ +de  + +GD ++v+++  +d W+ +++  +Gr G+vP++yve
  EEA22187.1 420 LYDFMAQGEDEVTVATGDEVVVLDDsKSDEWWMVRRikNGREGVVPSSYVE 470
                 7*********************955269******9778************7 PP

  == domain 4  score: -3.0 bits;  conditional E-value: 3.5
       SH3_9  13 LsLqrGDvitvi 24 
                 L L +GD+++v+
  EEA22187.1 703 LGLKEGDILRVM 714
                 6699*****996 PP

>> SH3_2  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.5   0.0     1e-10   2.1e-07       4      56 ..       9      64 ..       6      65 .. 0.88
   2 !    9.7   0.0   0.00034      0.68       2      55 ..      71     121 ..      70     123 .. 0.91
   3 !   26.1   0.0   2.6e-09   5.1e-06       8      56 ..     423     471 ..     417     472 .. 0.87
   4 !    6.1   0.0    0.0044       8.8       9      49 ..     696     749 ..     689     751 .. 0.64

  Alignments for each domain:
  == domain 1  score: 30.5 bits;  conditional E-value: 1e-10
                ESS-B-SCGCCB--B-TTEEEEEE..EEEECTTEEEEEEC......CCEEEEEGCGEEE CS
       SH3_2  4 aiedyvgedkseLsfkkGdvikvlslgskdsdgwwegevg......GrvGlfPsslvee 56
                a+ dy ++ ++eL+++++d++++l   +kd+d+ww++ ++        vGl+P+++v+e
  EEA22187.1  9 AVYDYQPQAEGELEIHENDLLYIL---DKDDDDWWKAKKKadpeddEPVGLVPNNYVQE 64
                7889********************...**********994456666666*********8 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.00034
                 EEESS-B-SCGCCB--B-TTEEEEEE..EEEECTTEEEEEECCCEEEEEGCGEE CS
       SH3_2   2 vraiedyvgedkseLsfkkGdvikvlslgskdsdgwwegevgGrvGlfPsslve 55 
                 ++a+ dy+++  +e+sf ++  + v+   ++ +++w ++ +g   G++P ++ +
  EEA22187.1  71 AKALYDYTRQTDEEISFSEDAELSVY---DTTDPDWTLVGSGTDFGFAPANYIQ 121
                 69999*********************...**********995555****99987 PP

  == domain 3  score: 26.1 bits;  conditional E-value: 2.6e-09
                 B-SCGCCB--B-TTEEEEEE..EEEECTTEEEEEE..CCCEEEEEGCGEEE CS
       SH3_2   8 yvgedkseLsfkkGdvikvlslgskdsdgwwegev..gGrvGlfPsslvee 56 
                 + ++ ++e +   Gd + vl   +++sd+ww +++  +Gr G++Pss+ve+
  EEA22187.1 423 FMAQGEDEVTVATGDEVVVL--DDSKSDEWWMVRRikNGREGVVPSSYVEI 471
                 5566677778889*******..999********999*************96 PP

  == domain 4  score: 6.1 bits;  conditional E-value: 0.0044
                 -SCGCCB--B-TTEEEEEE............EEEECTTEEEEEE...CCCEEEE CS
       SH3_2   9 vgedkseLsfkkGdvikvls..........lgskdsdgwwegev...gGrvGlf 49 
                 ++e  + L +k+Gd+++v +           +s+ ++ +  ge    +G  Glf
  EEA22187.1 696 TPETLRTLGLKEGDILRVMRyldtmfnrtgSKSRLRNVSFGGEEvigNGETGLF 749
                 5555566************98888888853333333333333222446666666 PP

>> DUF1720  Domain of unknown function (DUF1720)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.8       2.1   4.1e+03       6      42 ..     832     867 ..     827     878 .. 0.52
   2 !    6.3  34.4    0.0066        13       2      74 ..     872     945 ..     861     952 .. 0.74
   3 ?   -5.2  50.8         9   1.8e+04      11      75 .]     977    1053 ..     939    1053 .. 0.82
   4 !   20.4  38.9   2.6e-07   0.00052       2      67 ..    1054    1118 ..    1053    1128 .. 0.86
   5 !   16.5   8.2   4.4e-06    0.0087      10      51 ..    1127    1173 ..    1119    1182 .] 0.55

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 2.1
     DUF1720   6 tGfqppqqqqpqqqqplqpqpTGfmpqqqtgq.glqpq 42 
                 t  + + +  + +++p    pTG m+  +  q +l+p 
  EEA22187.1 832 TAAAAAAPAPVEPPKPAP--PTGAMADLSLLQaPLKPT 867
                 555555555555553333..377776665555544443 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0066
     DUF1720   2 qpqqtGfqppqqqqpqqq....qplqpqpTGfmpqqqtgqglqpqpTG.ggqfap...glqpqqTGfqeqaqqglqPqaTG 74 
                 qp +    p+    p+ +    +p+ pq+T  ++ +q+ ++ qpq+TG ++ f +   +lqpqqT++      + qPq  G
  EEA22187.1 872 QPTPPAAVPAAAVPPP-TvpvlAPMLPQQTATLSYPQPAAPQQPQATGaNPGFFQqlgPLQPQQTAV------PNQPQGMG 945
                 4433333333333333.258889***********999999********9766666699*********......55555444 PP

  == domain 3  score: -5.2 bits;  conditional E-value: 9
     DUF1720   11 pqqqqpqqq..qplqpqpTGfmpqqqtgq............glqpqpTGggqfapglqpqqTGf....qeqaqqglqPqaTGf 75  
                  pq +q+++   +plqpq TG+  + ++ +             +qpq+ G      +lqpq T+f    q+q q+gl+Pq+TGf
  EEA22187.1  977 PQDFQQSPFaaPPLQPQLTGISRNAPQLAptgqslaelnqqRFQPQQYG------QLQPQLTAFpqqqQPQFQNGLMPQPTGF 1053
                  3333333336779********9999998899999999999999999999......6********9988888899999*****9 PP

  == domain 4  score: 20.4 bits;  conditional E-value: 2.6e-07
     DUF1720    2 qpqq.tGfqppqqqqpqqqqplqpqpTGfmpqqqtgqglqpqpTG.ggqfapglqpqqTGfqeqaqqg 67  
                  qpq+  Gfq++qqqq+qq +++ pqpTGf+++ ++  + qp++TG +g ++p lqpqqT++ +   ++
  EEA22187.1 1054 QPQSqFGFQQQQQQQQQQFAGMAPQPTGFGGFSPP--PQQPMATGiNGMLPPALQPQQTAV-NGFGTS 1118
                  9998789*99999999999***************9..9**********9999********9.444444 PP

  == domain 5  score: 16.5 bits;  conditional E-value: 4.4e-06
     DUF1720   10 ppqqqqpqqqqplqpqpTGfmpqqqtgq.....glqpqpTG.ggqfap 51  
                  pp +q+p    plqpq+TG  p+  +g+      l pqpTG    +a+
  EEA22187.1 1127 PPIPQMPTVA-PLQPQKTGPAPPVRFGVkhdakKLTPQPTGmRANLAQ 1173
                  5555555555.6666666666666666666666666666663333333 PP

>> SH3_10  SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.65   1.3e+03      20      49 ..      12      44 ..       7      50 .. 0.79
   2 ?    3.4   0.0     0.042        84      13      52 ..      69     110 ..      62     118 .. 0.79
   3 !   13.3   0.0   3.2e-05     0.064      24      59 ..     429     466 ..     381     471 .. 0.82

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.65
      SH3_10 20 dykqa...evsiekgeevtLldnsdrekWkVqt 49
                dy+ +   e +i++++ + +ld  d+  Wk ++
  EEA22187.1 12 DYQPQaegELEIHENDLLYILDKDDDDWWKAKK 44
                55544445899******************9765 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.042
      SH3_10  13 iaveALcdykqa...evsiekgeevtLldnsdrekWkVqtssG 52 
                  +++AL dy+ +   e+s++++ e+ + d +d+  W++  s +
  EEA22187.1  69 YKAKALYDYTRQtdeEISFSEDAELSVYDTTDPD-WTLVGSGT 110
                 5789999997655559****************97.99877665 PP

  == domain 3  score: 13.3 bits;  conditional E-value: 3.2e-05
      SH3_10  24 aevsiekgeevtLldnsd.rekWkVqtss.GaemtvPg 59 
                 +ev++  g+ev++ld s+ +e W V++++ G e  vP+
  EEA22187.1 429 DEVTVATGDEVVVLDDSKsDEWWMVRRIKnGREGVVPS 466
                 4999****9998887776156689999988*******9 PP

>> SAM_4  SAM domain (Sterile alpha motif)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.0   2.5e-06     0.005       8      73 ..     658     722 ..     652     730 .. 0.89

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 2.5e-06
       SAM_4   8 tsewiqffkeagipaglavnyavsfvdnriqknmlldlskeimnelgitvvgdiiailkhakvvyr 73 
                   +w +ff +ag+ +     ya  f  + ++ ++l d++ e +  lg+   gdi+ ++++  +++ 
  EEA22187.1 658 EYDWFDFFLKAGVGPHQCERYAQNFSKDSMDEAILPDITPETLRTLGLK-EGDILRVMRYLDTMFN 722
                 568********************************************97.5*****9998777665 PP

>> SAM_1  SAM domain (Sterile alpha motif)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0     3e-05      0.06      16      63 ..     674     720 ..     663     721 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 3e-05
                 TSGGGHHHHHTTTSSHHHHTTSCHHHHHHCTTTSHHHHHHHHHHHHHH CS
       SAM_1  16 glgqYadlFrageidgdaLlllteddLeklgvtllGHrkkIlyaIqrL 63 
                  +++Ya +F++  +d   L ++t ++L+ lg +  G+ ++ +++++++
  EEA22187.1 674 QCERYAQNFSKDSMDEAILPDITPETLRTLGLKE-GDILRVMRYLDTM 720
                 689******99999*******************9.********99876 PP

>> SH3_3  Bacterial SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0      0.69   1.4e+03      27      54 ..      31      62 ..      24      63 .. 0.65
   2 ?   -2.0   0.0       2.4   4.7e+03      25      54 ..      93     120 ..      88     121 .. 0.66
   3 ?   11.5   0.8   0.00014      0.28      18      55 .]     432     470 ..     426     470 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.69
       SH3_3 27 vleetgggeWykv.....rtddgteGwvssgyl 54
                +l++++++ W+k       +dd  +G v + y+
  EEA22187.1 31 ILDKDDDD-WWKAkkkadPEDDEPVGLVPNNYV 62
                67777777.***965543222222488877776 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 2.4
       SH3_3  25 VevleetgggeWykvrtddgt.eGwvssgyl 54 
                 ++v + t+ + W  v   +gt  G++ + y+
  EEA22187.1  93 LSVYDTTDPD-WTLV--GSGTdFGFAPANYI 120
                 6666666665.****..44442488888886 PP

  == domain 3  score: 11.5 bits;  conditional E-value: 0.00014
       SH3_3  18 tlpyGekVevleetgggeWykv.rtddgteGwvssgyls 55 
                 t+  G++V vl++++ +eW+ v r  +g+eG v s+y++
  EEA22187.1 432 TVATGDEVVVLDDSKSDEWWMVrRIKNGREGVVPSSYVE 470
                 7899******************6666666**99999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1182 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       851  (0.047465); expected 358.6 (0.02)
Passed bias filter:                      389  (0.0216967); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.87u 0.31s 00:00:01.18 Elapsed: 00:00:00.50
# Mc/sec: 7044.24
//
Query:       EEA22188.1  [L=491]
Description: serine-threonine protein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.4e-21   75.4   0.1    7.9e-21   74.6   0.1    1.4  1  Pkinase          Protein kinase domain
    1.9e-14   53.6   0.0    3.9e-14   52.6   0.0    1.5  1  Pkinase_Tyr      Protein tyrosine kinase
  ------ inclusion threshold ------
      0.031   13.2   0.0      0.053   12.5   0.0    1.3  1  Pox_ser-thr_kin  Poxvirus serine/threonine protein kinase
      0.043   13.7   0.0       0.22   11.4   0.0    1.9  2  APH              Phosphotransferase enzyme family


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.6   0.1   1.8e-24   7.9e-21      27     258 ..       1     271 [.       1     275 [. 0.75

  Alignments for each domain:
  == domain 1  score: 74.6 bits;  conditional E-value: 1.8e-24
                 EEEEEEECHCHCHHHHHHHHHHHHHHHHHS.....CTTB--EEEEEEESSEEEEEEE--TTEBHHHHHH....HHSS--HHHHHHHHHHHHHHHHHHHH CS
     Pkinase  27 vAvKkikkekakkkkekkvlrEikilkklk.....hpnivrlyevfeekdelylvleyveggeladlle....rkgslseeeakkiakqilegleylHs 116
                 +AvK+++ +++++ ++     E  +l +++     h n++  y+++   ++ +l+l + + g+l+d+++    r+++ +++++   +  ++ +l++l +
  EEA22188.1   1 MAVKIFNSDSTNDFEN-----ERDVLSRIRnsrsgHVNVLVNYGSLVYGEHHMLFLPWTNLGTLDDFISfeehRDTTAKKRNIIYCIIDVADALAWLTK 94 
                 5888888887777554.....5555555544446799**9999*9999*********************987766777788888888888899999987 PP

                 TT...........EE-SS-SGGGEEEETTTE......EEE-SGTTSEESSSSCSBCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHHHHHSS-STT CS
     Pkinase 117 kg...........iiHrDlKpeNiLidekge......lKitDFGlakelessskltsfvgtseYlAPEvlkeneyskkvDvWslGvilyelltgkppfs 198
                  +           ++H+D+Kp+NiLi  +        +K++DFG+a   +s  +++s+   s+Y+APE  ++ +++k++DvW +G+il+ +l  ++  +
  EEA22188.1  95 LKislphkfrevqVMHCDIKPQNILIFPDSTrengfiFKVSDFGHAFMSSS-IETQSRRYESTYCAPETRERGSVEKTSDVWPYGCILLLVLIFTTRGP 192
                 7777777788889*************8444346799*********976666.55**********************************99988877777 PP

                 TSSHHHHHHHHHHTHHHHHHHCT....SHH...HHHTTS.................-HHHHHHHHHHT-SSGCCSTTHHHH CS
     Pkinase 199 gekgkekvekeldqlekilkilg....etkeklpeasei.................seeakdllkkllkkdpkkRltaeel 258
                 +e    + +++l +  +i    +    + ke++  + +i                 +   k l +++l  d+k+R t++ +
  EEA22188.1 193 QEII--DLRADLSRRSTIDTFYQstnyQLKESVSDWIDIlrdgkisnadinetemtKAMGKILHDDILVSDHKSRKTMDVI 271
                 3333..334444443333333332224444455555555899999999999777755555666677888888888887655 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.6   0.0   8.6e-18   3.9e-14      32     197 ..       2     183 ..       1     227 [. 0.77

  Alignments for each domain:
  == domain 1  score: 52.6 bits;  conditional E-value: 8.6e-18
                  EEEEESTTSSHHHHHHHHHHHHHHHTS-.....BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHT..CTTTSBHHHHHHHHHHHHHHHHHHHHT CS
  Pkinase_Tyr  32 avKtlkeeateeekeelleeakimkklk.....hpnivkllgvctkeepllivteyvkgGdLlkfLrkk..ekekltlkdllsfalqvAkGmeyLesk 122
                  avK++++++t    +++ +e +++++++     h n++  +g  + +e++++ + + + G+L++f+  +  ++++ + ++++ ++++vA+++++L + 
   EEA22188.1   2 AVKIFNSDST----NDFENERDVLSRIRnsrsgHVNVLVNYGSLVYGEHHMLFLPWTNLGTLDDFISFEehRDTTAKKRNIIYCIIDVADALAWLTKL 95 
                  6777754444....55777777776663244448999999*****9*******************98761144455556789999**********875 PP

                  T...........EEEST-SGGGEEEEE......TTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSEEEHHHHHHHHHHHHHH CS
  Pkinase_Tyr 123 k...........lvHrdlaarNvLlse......nkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekkftsksDvWsfGvllwE 197
                  k           ++H d+  +N+L+        + + k+sDfG a       +  ++++++    ++apE+ +++++++ sDvW +G +l  
   EEA22188.1  96 KislphkfrevqVMHCDIKPQNILIFPdstrenGFIFKVSDFGHAFMS----SSIETQSRRYESTYCAPETRERGSVEKTSDVWPYGCILLL 183
                  43333333334389***********754555535589******88755....7778899999*************************87754 PP

>> Pox_ser-thr_kin  Poxvirus serine/threonine protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   1.2e-05     0.053     299     317 ..     107     125 ..      88     145 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.2e-05
  Pox_ser-thr_kin 299 nflhvDlkPdniLifdske 317
                      + +h D+kP+niLif++++
       EEA22188.1 107 QVMHCDIKPQNILIFPDST 125
                      579************8733 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0      0.17   7.5e+02      24      84 ..       2      61 ..       1      89 [. 0.77
   2 ?   11.4   0.0   4.8e-05      0.22     162     191 ..      98     131 ..      58     144 .. 0.75

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.17
                EEEEE-TTS-HHHHHHHHHHHHHHHHTT-.B--B-CTTBS-EEETTEEEEEEE----EE-SS CS
         APH 24 vlrrnpparaaeeirrevallrlLakagv.pvPevlagdtddeeigllfalieyvpgrsllr 84
                ++++++   + +++++e ++l  ++++   +v +++ ++   +++  +++++++    +l++
  EEA22188.1  2 AVKIFNSD-STNDFENERDVLSRIRNSRSgHVNVLVNYGSLVYGEH-HMLFLPWTNLGTLDD 61
                68888888.99**********9999887778888888765555554.788888877777766 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 4.8e-05
                 S....SS-EEEE-SS-SGGGEEEC..TTEEEEE- CS
         APH 162 g....elptvllHgDlhpgNllvdpddgrvtGvi 191
                 +      + +++H+D++p+N+l+ pd +r  G+i
  EEA22188.1  98 SlphkFREVQVMHCDIKPQNILIFPDSTRENGFI 131
                 3333556789**************9999888877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (491 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       683  (0.0380947); expected 358.6 (0.02)
Passed bias filter:                      514  (0.0286686); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.64u 0.30s 00:00:00.94 Elapsed: 00:00:00.50
# Mc/sec: 2980.26
//
Query:       EEA22189.1  [L=495]
Description: amino acid transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.1e-27   94.9  27.5    2.7e-26   92.2  27.5    1.8  1  AA_permease     Amino acid permease
    1.1e-17   64.0  28.4    1.4e-17   63.7  28.4    1.1  1  AA_permease_2   Amino acid permease
  ------ inclusion threshold ------
       0.22   10.3  12.2       0.46    9.3  12.2    1.5  1  Spore_permease  Spore germination protein


Domain annotation for each model (and alignments):
>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.2  27.5   4.5e-30   2.7e-26       1     347 [.      80     467 ..      80     479 .. 0.93

  Alignments for each domain:
  == domain 1  score: 92.2 bits;  conditional E-value: 4.5e-30
  AA_permease   1 hvlvialggviGtglfvglgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgpelGfviGlnylfswitvlaleltaas 98 
                  h+++ ++   iG+g++v++g+  + +Gp++a+ ay+l g+ + +v  +++ +    p++g+   y+++ l++e G vi + y++++++ + +  ++++
   EEA22189.1  80 HIFFLSVSTCIGLGFYVRTGNMDGFGGPGAAIYAYALLGILSSMVLHNIATMLRVWPVAGALLLYVKHLLDEEIGIVITIVYWLTYCFSASALAATVA 177
                  89999************************************************************************************999999999 PP

  AA_permease  99 iliqfwelvtdlpkawvtgavflvvl.liinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkga.....gfrflgdngsifknnlppgf 190
                   l+ +   + ++  a v +++f++++ +++n +++  ++ +e+ l  +k++ ++  ii   ++++++ +n+       gf  + ++++  +n + +g 
   EEA22189.1 178 DLLAIF--YLSNG-ATVAIMIFVTAIpIALNSLSLNRFRDIEIGLGAFKLVVALVIIIAMNVTNSEQSLNDNEnslpgGFNLTANHLQARENLFLGG- 271
                  999999..88888.888899998777488**********************9999999999999999999888899*99999999999999999999. PP

  AA_permease 191 a.keeegafknfisvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYv...............lsllligllvprndlgllndsasa 272
                  +  ++ g+f +f+s +   +f++ Gie +a++a+E+   e+     ++++ +++t  +                 ++ ++++ +p +dl  +  s++ 
   EEA22189.1 272 RpHQTAGWFGGFMSSIFLGSFSLVGIEVIAVTAQETVVYEQRNSELTSRTHWTVTDQFSwparwvpgvvtglyiWGAWAVTANIPSTDLPQFYPSNNL 369
                  77*****************************************************9999999999999999999999999999999999888877777 PP

  AA_permease 273 .........aspfvifi.kesgvsvlaplinaviltaalssansslysasRvlyslakdglaP.............kvlkkvskrgvPlraillsmii 347
                           as+f+ +  ++   ++la  +++++ ++++++a ++ y++sR+ly +a d +                + +  +k+gvP +a+l+s+ +
   EEA22189.1 370 tgftvgpcqASIFIDAAcQNGQGNALAKALTVLLMISLTFTATAAFYASSRTLYGFASDMIQSrqvqptsflgtifGFCASKNKHGVPQNAVLVSAWL 467
                  99***********98752666789***********************************999888999**999999888999************9765 PP

>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.7  28.4   2.3e-21   1.4e-17       5     331 ..      80     467 ..      76     489 .. 0.79

  Alignments for each domain:
  == domain 1  score: 63.7 bits;  conditional E-value: 2.3e-21
  AA_permease_2   5 safalvigsvigsgifvkn....laasggpalilwvwiavligslavllvyaElssalprsgGiyvytkaafgkkvaflsawfnwfayvpvlasil 96 
                      f+l+++++ig+g++v +    +++ +g+a+  + ++++l    +vl  +a++  ++p  g +  y+k++  + ++ + ++ +w+ y +++ s l
     EEA22189.1  80 HIFFLSVSTCIGLGFYVRTgnmdGFGGPGAAIYAYALLGILSS--MVLHNIATMLRVWPVAGALLLYVKHLLDEEIGIVITIVYWLTYCFSA-SAL 172
                    579**************98878888888888887777777765..455555666566*******************************9988.334 PP

  AA_permease_2  97 svaasyllnalgpdlqgntwltyliaiaililvalinirgikesakiqnilgilkillpliiliilglitvdgggfssl.............stet 179
                    ++ ++ ll +++     ++ +t+ i+i+++++ +++n+++ +  + i   lg +k++ + +++ii+  +t + +  +++             +   
     EEA22189.1 173 AATVADLLAIFY----LSNGATVAIMIFVTAIPIALNSLSLNRFRDIEIGLGAFKLV-VALVIIIAMNVTNSEQSLNDNenslpggfnltanH--- 260
                    444444444443....456699**********************************6.55555555555554444443356666665544440... PP

  AA_permease_2 180 dt...........ffpn.gwpg.vllgllivlwsfdGfesaanvsee...vkkkdvpkai..............figllivlvlyllvniaflgvv 245
                                  +++ gw g ++++++   +s++G+e++a+ ++e    ++++ +++                ++ ++v++ly+  + a+++ +
     EEA22189.1 261 -LqarenlflggrPHQTaGWFGgFMSSIFLGSFSLVGIEVIAVTAQEtvvYEQRNSELTSrthwtvtdqfswpaRWVPGVVTGLYIWGAWAVTANI 355
                    .04455565554433334777657889999*****************9754458888888888999****************************** PP

  AA_permease_2 246 pddei......anlsnlgsv.........aalffeavg....gkvvaiivvilialsllgaintavigssrvlealard.............gvlP 309
                    p   +      +      ++         a++f +a+     g ++a ++ +l+++sl + +++a+++ssr+l+ +a d             g++ 
     EEA22189.1 356 PSTDLpqfypsN------NLtgftvgpcqASIFIDAACqngqGNALAKALTVLLMISLTFTATAAFYASSRTLYGFASDmiqsrqvqptsflGTIF 445
                    **9995555432......33444568899888888874443366**************************************************** PP

  AA_permease_2 310 rffakvnkfgspiraiiltaiv 331
                     f a+ nk+g p +a+ ++a +
     EEA22189.1 446 GFCASKNKHGVPQNAVLVSAWL 467
                    ****************998865 PP

>> Spore_permease  Spore germination protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3  12.2   7.6e-05      0.46       2     158 ..      76     235 ..      75     242 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 7.6e-05
  Spore_permease   2 istkqlfvlivsfqlGvgiltlprsvaeqatpdgWi..svllagiiililvllmlkllkkfpektliellkkilgkwLGsllsilfilyFlllaa 94 
                     + ++ +f+l vs+ +G g+ +  + +    +p + i    ll+++  ++l  +++ l        l+ ++k++l   +G ++ i++ l + + a+
      EEA22189.1  76 LRSIHIFFLSVSTCIGLGFYVRTGNMDGFGGPGAAIyaYALLGILSSMVLHNIATMLRVWPVAGALLLYVKHLLDEEIGIVITIVYWLTYCFSAS 170
                     66778899999999999999999988888877776622469999998888888877777778999****************************** PP

  Spore_permease  95 felRefseliqvflledtplwiiilllllvilYlvvkGieslar.eflfiivilliilllillfs 158
                       + + ++l+ +f l +  +++i++++ ++ + l + +++ +   e+ + ++ l+++l++i+ ++
      EEA22189.1 171 ALAATVADLLAIFYLSNGATVAIMIFVTAIPIALNSLSLNRFRDiEIGLGAFKLVVALVIIIAMN 235
                     ****************************9999999999999875544444444555555444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (495 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       658  (0.0367003); expected 358.6 (0.02)
Passed bias filter:                      297  (0.0165653); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.48
# Mc/sec: 3116.44
//
Query:       EEA22190.1  [L=621]
Description: pogo transposable element, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.9e-23   82.0   0.0    7.9e-23   81.0   0.0    1.5  1  DDE_1         DDE superfamily endonuclease
      9e-09   35.2   0.3    3.1e-08   33.5   0.3    2.0  1  HTH_Tnp_Tc5   Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
      0.026   14.6   0.1       0.53   10.5   0.0    2.7  3  Pcc1          Transcription factor Pcc1
      0.055   12.4   1.6      0.083   11.8   1.6    1.2  1  Amidase       Amidase


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.0   0.0   1.8e-26   7.9e-23       2     175 .]     193     368 ..     192     368 .. 0.89

  Alignments for each domain:
  == domain 1  score: 81.0 bits;  conditional E-value: 1.8e-26
       DDE_1   2 erltvllcanaagsekLkplvigkak..sprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrleaekrk..ilLlldssrshetvel.le 94 
                 +++ ++++++ a++  + p +i+ ak  +++ ++    ++++  + +  ++ +w+ ++++ +WL +vfdk ++++ ++   lL+ld+++sh t+ + + 
  EEA22190.1 193 REWITTIGCICANGTAISPALIYMAKsgNLQDSWLQDFDAEQHRCFFATSESGWTNNEVGFAWLvNVFDKETKSQASRgwRLLILDGHGSHVTMRFiEY 291
                 678999****************9665226888999999***********************************666652267**************999 PP

       DDE_1  95 selqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                 ++++ i l+++Pa+s+++lqP d+ ++s+l + Y +ql + +++  +        lt +d+++   ++w+  +++e+i saf
  EEA22190.1 292 CDKNRILLAIFPAHSTHTLQPPDVAIFSPLSTAYTEQL-RRFINDCQGFTR----LTKRDFFRLFWASWEaTFTSENILSAF 368
                 **********************************8765.556666655555....9**************99******9987 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.5   0.3     7e-12   3.1e-08       2      60 ..      59     108 ..      58     115 .. 0.91

  Alignments for each domain:
  == domain 1  score: 33.5 bits;  conditional E-value: 7e-12
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh 60 
                  +e+ + L++Wi+ql+erg p+t++++ + A+e+         + + ++k+W  r++k h
   EEA22190.1  59 KEQSRTLIKWINQLTERGLPPTNSMLENFAREI---------SGKEPGKNWASRWLKAH 108
                  68999****************************.........67889**********99 PP

>> Pcc1  Transcription factor Pcc1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00012      0.53      12      50 ..       5      43 ..       1      59 [. 0.88
   2 ?    0.7   0.0      0.13   5.8e+02      49      66 ..     405     422 ..     402     423 .. 0.91
   3 ?   -2.8   0.1       1.6   7.2e+03      12      36 ..     556     583 ..     553     608 .. 0.57

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00012
                HHHHHHHHHHHHHCHC-TTECEEEEEEETTEEEEEEEES CS
        Pcc1 12 rlAsialrtLqvDkelsplavkrslslegnvLqveykAt 50
                +lA  alr+L++D++++ + v r++ ++++ L  +++  
  EEA22190.1  5 ELALEALRSLKPDEKPNISLVARTYGVNQSNLSKRFRGV 43
                78888********9999888***********99998875 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.13
                 ESSHHHHHHHHHHHHHHH CS
        Pcc1  49 AttnrmLRvavngflesl 66 
                 A++ r LR  v+g++e+l
  EEA22190.1 405 AEDWRRLRKLVQGVFEDL 422
                 9999************98 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 1.6
                 HHHHHHHHHHHHH..CHC-TTE.CEEEE CS
        Pcc1  12 rlAsialrtLqvD..kelspla.vkrsl 36 
                 +lA+ a   Lq D  + +s ++  k+++
  EEA22190.1 556 ELAKLAHLQLQNDvlATPSAPKrAKKQV 583
                 6777777778877553333333333333 PP

>> Amidase  Amidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   1.6   1.9e-05     0.083     309     396 ..     498     589 ..     470     612 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 1.9e-05
                 ---SS-SCCCCCCCHHHHCCS-HHHHHHHHHHHHHCSCCCCCCCHHHHHHHHH.HHHHHHHHHCCC...BSEEEEESSSSS--BCCCCCHHH CS
     Amidase 309 erlsetkvlsellpksraellgeevkrrielgnyalsaeasskyylkaqkvrr.llrrefakafee...lDvllsPtaptpaprlgekdkti 396
                 +  + ++  +++  k+ +++l+++ k + +    ++ +e++++ +++a++ +r   ++e+ak+ +     Dvl++P+ap+ a+++  k+ ++
  EEA22190.1 498 KDEQAAQEQARKDDKKLQQELTKQAKEQEKAERAQIRQEKQEQRLQEATEKQRlKDEQELAKLAHLqlqNDVLATPSAPKRAKKQVSKQVKV 589
                 2333344445666667777777777777777777777777777777777666656667777765557778*************998887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (621 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3090  (0.172346); expected 358.6 (0.02)
Passed bias filter:                      873  (0.0486921); expected 358.6 (0.02)
Passed Vit filter:                       170  (0.00948185); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.92u 0.31s 00:00:01.23 Elapsed: 00:00:00.48
# Mc/sec: 3908.59
//
Query:       EEA22191.1  [L=458]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0093   15.3   5.2      0.025   13.9   5.2    1.7  1  CorA      CorA-like Mg2+ transporter protein


Domain annotation for each model (and alignments):
>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   5.2   1.4e-06     0.025     149     248 ..     240     362 ..     226     366 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.4e-06
        CorA 149 ilrelaqlrrrlvklrralapnrevlkrllakaddkllddedkeylrdlldeler....llemlealrerleslqdtyssllser.............. 229
                  l++l +l++rl+ lr+++ +++++l+ l++  +++ +   dk y+++ ld++e      ++ l+ l +r+ s+ +++s+++s +              
  EEA22191.1 240 SLSSLHNLETRLAPLRSIFPATKRILQLLIK--LNNAYAHPDKVYINERLDNMEEminsFDDNLQYLMSRVASICSLLSNTISLKnentsnqvsnsmlk 336
                 688999999*****************66666..555555555556555555555544449999999999**************9999999999999999 PP

        CorA 230 .......lNrvmkvLTvltaiflPlT 248
                           +++v+T++t i lP+T
  EEA22191.1 337 ynrftvdDSATVRVITLVTLIYLPPT 362
                 99999888889999999999999999 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (458 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       664  (0.037035); expected 358.6 (0.02)
Passed bias filter:                      488  (0.0272185); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 3174.47
//
Query:       EEA22192.1  [L=515]
Description: misfolded glycoproteins degradation protein Yos9, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.1e-21   75.8   0.8    1.4e-20   74.0   0.8    2.0  1  PRKCSH        Glucosidase II beta subunit-like protein
  ------ inclusion threshold ------
      0.016   15.3   0.0      0.031   14.4   0.0    1.5  1  bPH_5         Bacterial PH domain
      0.042   13.5   0.1      0.095   12.4   0.1    1.7  1  PRKCSH_1      Glucosidase II beta subunit-like protein
       0.33   11.0   1.1          5    7.2   0.0    2.5  3  P_proprotein  Proprotein convertase P-domain


Domain annotation for each model (and alignments):
>> PRKCSH  Glucosidase II beta subunit-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.0   0.8   3.2e-24   1.4e-20       2      81 .]     176     270 ..     175     270 .. 0.89

  Alignments for each domain:
  == domain 1  score: 74.0 bits;  conditional E-value: 3.2e-24
                 -EEEEEETTEEEEEETTTEEEEE-E..........ETTEE-S--EEEEEE.......EEEEEEE-------.....---S--EEEEEEEEE-SB- CS
      PRKCSH   2 kCvsskegwwtYelCygkkvrQfhe..........pekekgksevvLGrf.....nkeehsewaekneaksystedeekqsnryislkyenGtkC 81 
                 +C+++ +gww+Y++Cy+k+v+Qfh+          p ++++ +++vLG+f     +++e+ +  ++++ak++s+e ++k+ +ry+++++++Gt+C
  EEA22192.1 176 TCMYYVSGWWSYSFCYKKQVKQFHAksgpgvpnypPIEDPTSHSFVLGKFqqdddDESETDSSSGSKHAKASSAELQTKGESRYLVQRLSGGTVC 270
                 8*************************************************8887744444555555555557*********************** PP

>> bPH_5  Bacterial PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   6.9e-06     0.031      43      99 ..     379     437 ..     368     438 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 6.9e-06
       bPH_5  43 gtskpgyalGrfkikdigkarmyatr.lkrvlllktkd.kiygisPedleeFkealesr 99 
                 g++++    Gr+   +  ++++ a+r + +++ l  kd k+y + P+++e+F+++l ++
  EEA22192.1 379 GSEGKVIEKGRMARIGEETVQIIAKReNGELVQLSNKDlKKYNLNPKEVEAFANQLDEK 437
                 666666667999999999********9****************************9876 PP

>> PRKCSH_1  Glucosidase II beta subunit-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   2.1e-05     0.095      84     150 ..     267     343 ..     163     347 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2.1e-05
                 -SB-.TTSSC-EEEEEEEE-SS..-EEEEEEEEETTEEEEEEEEGGG--XXXXX.......XXXXXXXXXXXXXXXX CS
    PRKCSH_1  84 GakC.WnGPvRsaiveveCGde..nelvsvseaekCeYllkvkspaaCsnvllk.......kslaeeeslanfkiae 150
                 G+ C   G +R+  v+++C  +  +++  + e   C Yl+++ +p  C++v ++       +s+   e+la+ +ia+
  EEA22192.1 267 GTVCdLTGTERKIEVQFHCHPQstDRIGWIKEQTTCSYLMVIYTPRLCHDVAFQlpqfedtHSIQCREILAPDEIAD 343
                 5556347999*********8752267889*******************77665411111113444445566665555 PP

>> P_proprotein  Proprotein convertase P-domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0      0.06   2.7e+02      35      65 ..      60      90 ..      50      92 .. 0.78
   2 ?   -3.5   0.1       2.4   1.1e+04      30      55 ..     220     244 ..     215     250 .. 0.48
   3 ?    7.2   0.0    0.0011         5      27      73 ..     407     452 ..     390     459 .. 0.74

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.06
                  --TT---SS-EEEEEEEESTTTTS---EEEE CS
  P_proprotein 35 rrgkdksrsgfldwtfmsthlwgeraeGeWk 65
                  r+++d ++s+ + ++  ++h+ ++r+ G Wk
    EEA22192.1 60 RSSNDVASSNIDSDKRDLQHHASQRPIGGWK 90
                  44457777777888888*************7 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 2.4
                   EEEE---TT---SS-EEEEEEEESTT CS
  P_proprotein  30 svLlnrrgkdksrsgfldwtfmsthl 55 
                   +vL + +++ ++ +  +d    s+h+
    EEA22192.1 220 FVLGKFQQD-DDDESETDSSSGSKHA 244
                   445444444.4444444555455544 PP

  == domain 3  score: 7.2 bits;  conditional E-value: 0.0011
                   S-EEEEE---TT---SS-EEEEEEEESTTTTS---EEEEEEEEESST CS
  P_proprotein  27 GtrsvLlnrrgkdksrsgfldwtfmsthlwgeraeGeWkLevkdsee 73 
                   G+ ++L n+  k+++ + ++ ++f  ++l +++  G+W+Le+ +s+ 
    EEA22192.1 407 GELVQLSNKDLKKYNLNPKEVEAF-ANQLDEKTKGGDWRLEIVESNG 452
                   667777777777555444444444.5669999999*******98655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (515 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       750  (0.0418317); expected 358.6 (0.02)
Passed bias filter:                      434  (0.0242066); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.44
# Mc/sec: 3551.14
//
Query:       EEA22193.1  [L=262]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.065   14.4   0.0       0.15   13.3   0.0    1.5  1  EthD      EthD domain


Domain annotation for each model (and alignments):
>> EthD  EthD domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   8.1e-06      0.15      40      81 ..     200     241 ..     175     248 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 8.1e-06
                 EEEEEEEEEBTTC--SEEEEEEEEESSHHHHHHHHCSHHHHH CS
        EthD  40 ateagvalagpgsdadyDgiaelwfdsleaflaafadpeyaa 81 
                 + e  +   ++++ +++ ++a ++++s+ +f  ++++p+y++
  EEA22193.1 200 YGEVINSSLQNQGKSPWEMVALVYYPSPLHFGDMLSSPDYKE 241
                 566666777889999*************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (262 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       610  (0.0340231); expected 358.6 (0.02)
Passed bias filter:                      537  (0.0299515); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.24s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 1844.28
//
Query:       EEA22194.1  [L=366]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
      0.087   13.0   0.0        0.2   11.9   0.0    1.5  1  PapD-like  Flagellar-associated PapD-like


Domain annotation for each model (and alignments):
>> PapD-like  Flagellar-associated PapD-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   1.1e-05       0.2      24      79 ..     292     349 ..     285     356 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 1.1e-05
   PapD-like  24 ltvellnvstvpcRyrvrlpavvkkllsveYkrqFvaPGl..tvklkvelsgaqplGe 79 
                 +tve+ n     +R   rlpa++k +   +Y+ + ++ G+  t+k++v  ++a++ G+
  EEA22194.1 292 RTVEVGNQDNIITRITTRLPASFKRFTCTQYEDGNLTSGIrqTRKIEVTTHSAEEEGH 349
                 68999999999****************************9666777788888888886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (366 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       710  (0.0396006); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.21s 00:00:00.70 Elapsed: 00:00:00.39
# Mc/sec: 2807.70
//
Query:       EEA22195.1  [L=378]
Description: pirin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-30  105.6   0.1    2.4e-30  104.7   0.1    1.5  1  Pirin     Pirin
    1.8e-23   82.8   0.0    9.3e-23   80.6   0.0    2.0  2  Pirin_C   Pirin C-terminal cupin domain
    4.9e-06   26.2   1.4    9.5e-05   22.0   1.1    2.3  2  Cupin_2   Cupin domain
  ------ inclusion threshold ------
      0.056   13.1   0.1       0.71    9.6   0.0    2.5  3  Cupin_3   Protein of unknown function (DUF861)


Domain annotation for each model (and alignments):
>> Pirin  Pirin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.7   0.1   5.3e-34   2.4e-30       2     108 .]      96     194 ..      95     194 .. 0.95

  Alignments for each domain:
  == domain 1  score: 104.7 bits;  conditional E-value: 5.3e-34
                 EEECCGTCC.TTCCEECTCEECCEEESS.S.ETTEEEET-EEEEEEEBSEEEEEEEECSEEEEEETTS-EEEEETT-EEEEE-TT-EEEEEEE-SS..S CS
       Pirin   2 vrvrralgkaaelqsvdpFlfldefdpaelevgeedvigagfpphphrgletvtylleGevehrDslGnkgvirpGdvqwmtAgsGivhsEmneee..e 98 
                 +rvrr++g+ ++l++++pFl+ld+f+     +g+    gagfp+hphrg et+tyll+G v+h+D +Gn+g+i pGd+q mtAg+Gi+h+Em++e+  +
  EEA22195.1  96 ARVRRSIGT-PKLRNFSPFLMLDHFT-----IGK----GAGFPDHPHRGQETITYLLSGGVDHEDFAGNRGTIGPGDLQFMTAGKGIMHAEMPHENedG 184
                 689999999.9**************9.....678....89*****************************************************999888 PP

                 S-EEEEEEEE CS
       Pirin  99 esleglqlWv 108
                 ++  g+qlWv
  EEA22195.1 185 SPNVGMQLWV 194
                 999******8 PP

>> Pirin_C  Pirin C-terminal cupin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0      0.51   2.3e+03      10      53 ..     125     171 ..     118     178 .. 0.69
   2 !   80.6   0.0   2.1e-26   9.3e-23       2     103 ..     251     359 ..     250     360 .. 0.91

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.51
                 -EEEEE--TT-EEEEEEEES-E...EESSTTEEE-TTEEEEE-SSSE CS
     Pirin_C  10 aelelplpegleaavyvleGel...evggerseieeeqlavlgdgds 53 
                 a +      g e++ y l+G +    + g+r +i +++l  +++g+ 
  EEA22195.1 125 AGFPDHPHRGQETITYLLSGGVdheDFAGNRGTIGPGDLQFMTAGKG 171
                 55554446788999999999996656666767787777777776655 PP

  == domain 2  score: 80.6 bits;  conditional E-value: 2.1e-26
                 EEEEE-TT-EEEEE--TT-EEEEEEEES-EEESSTT...EEE-TTEEEEE-.SSSEEEEE--S...S-EEEEEEEE----S--EEETTEEESSHHHHHH CS
     Pirin_C   2 ldltleagaelelplpegleaavyvleGelevgger...seieeeqlavlg.dgdslvvkaee...kgarvlLlaGePlgepvvqyGpfVmntkeeieq 93 
                 +d+++++g ++++ lp g++a++y+leG+ ++ +++   ++i++ + +v++ +gd+++    +   +++r++L+aG+Pl+++vvqyGpfV  +kee+ q
  EEA22195.1 251 FDISIKPGGKVKQILPLGWNAFAYTLEGTTNFVTDNgdsKPIKQFHNVVFQqSGDHIEAYVPDnaeETSRFILVAGQPLNQEVVQYGPFVCTSKEEVYQ 349
                 79****************************9999988889**********997777776544444699******************************* PP

                 HHHHHHTT-T CS
     Pirin_C  94 afedyregrf 103
                 a+ d+++ ++
  EEA22195.1 350 AMLDFQSAKN 359
                 ******9987 PP

>> Cupin_2  Cupin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.0   1.1   2.1e-08   9.5e-05       3      52 ..     119     169 ..     117     185 .. 0.92
   2 ?    1.9   0.0     0.041   1.9e+02      19      50 ..     269     301 ..     252     308 .. 0.67

  Alignments for each domain:
  == domain 1  score: 22.0 bits;  conditional E-value: 2.1e-08
                 EEEETTEEEEEECSSSEEEEEEEEESEEEEE.ECTEEEEEETTEEEEE-TT CS
     Cupin_2   3 velppGesapshrHpgedeffyVleGegelt.vdgeeveleaGdsvyfpag 52 
                 +++ +G+ +p h H+g++ + y l+G +  +   g++ ++++Gd+ +  ag
  EEA22195.1 119 FTIGKGAGFPDHPHRGQETITYLLSGGVDHEdFAGNRGTIGPGDLQFMTAG 169
                 78999****************************************999998 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.041
                 EEEEEEEEESEEEEE.ECTEEEEEETTEEEEE- CS
     Cupin_2  19 edeffyVleGegelt.vdgeeveleaGdsvyfp 50 
                   +f y leG+  +   +g   ++++   v+f 
  EEA22195.1 269 WNAFAYTLEGTTNFVtDNGDSKPIKQFHNVVFQ 301
                 4499*******9988556777777766666665 PP

>> Cupin_3  Protein of unknown function (DUF861)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.0   0.00016      0.71      19      59 ..     127     169 ..     120     176 .. 0.87
   2 ?   -2.9   0.0       1.3   5.8e+03      33      48 ..     222     237 ..     214     250 .. 0.72
   3 ?    0.1   0.0      0.15   6.5e+02      26      48 ..     270     292 ..     255     303 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00016
                 EEECESS.EEEE.EEEECEEEEEETTTEEEEEETTEEEEE-TT CS
     Cupin_3  19 frltyee.dEfc.yileGevkvtpeggetvelraGDlvvlpkg 59 
                 f+ +  + +E++ y+l+G v+ ++  g++ ++++GDl ++ +g
  EEA22195.1 127 FPDHPHRgQETItYLLSGGVDHEDFAGNRGTIGPGDLQFMTAG 169
                 5566666688888************************999987 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.3
                 ECEEEEEETTTEEEEE CS
     Cupin_3  33 eGevkvtpeggetvel 48 
                  G+v++++ +g+ + +
  EEA22195.1 222 DGRVSIKVISGQSHGV 237
                 5888888888877655 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.15
                 EEEEEEEECEEEEEETTTEEEEE CS
     Cupin_3  26 dEfcyileGevkvtpeggetvel 48 
                 + f+y leG   ++ ++g    +
  EEA22195.1 270 NAFAYTLEGTTNFVTDNGDSKPI 292
                 56899*******99998876544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (378 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       432  (0.024095); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.58u 0.25s 00:00:00.83 Elapsed: 00:00:00.47
# Mc/sec: 2406.90
//
Query:       EEA22196.1  [L=776]
Description: mannosyltransferase PMTI [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.8e-84  282.6  17.6    5.6e-84  281.5  17.6    1.5  1  PMT              Dolichyl-phosphate-mannose-protein mannosylt
    9.9e-69  230.9   2.8    9.9e-69  230.9   2.8    3.1  4  PMT_4TMC         C-terminal four TMM region of protein-O-mann
    3.2e-18   66.2   0.7    5.9e-18   65.4   0.7    1.4  1  MIR              MIR domain
  ------ inclusion threshold ------
        1.5    9.0  24.8      0.028   14.6   3.3    4.0  5  PMT_2            Dolichyl-phosphate-mannose-protein mannosylt


Domain annotation for each model (and alignments):
>> PMT  Dolichyl-phosphate-mannose-protein mannosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  281.5  17.6   1.3e-87   5.6e-84       3     245 .]      54     302 ..      52     302 .. 0.96

  Alignments for each domain:
  == domain 1  score: 281.5 bits;  conditional E-value: 1.3e-87
         PMT   3 ltllallirlwrlslpnsvvfdevhfgkfasdYlehsffmdvhpplgkmllalggyLagkdgnftfesigaeyypenvpyvslRlfsallgslivplvy 101
                 +t+la+++r+w +++p +vvfdevhfgkfas+Yl++++f+dvhpp++k+l+a++g+L g+dg+ftfe+ig++y +++vpy+++R+++a+lgsl+ p+v+
  EEA22196.1  54 MTALAFVTRFWMINYPDEVVFDEVHFGKFASYYLQRTYFFDVHPPFAKLLFAFVGWLVGYDGSFTFENIGDSYITNKVPYLAYRALPATLGSLTIPVVF 152
                 799************************************************************************************************ PP

         PMT 102 ltllelgfskltallaallvllenslitlsryilldspLlfftllsmyclvkfe..rkapfsrswwlwllltgvalglavsvKwvglftvllvgllliw 198
                  ++ e+g+s  +++la+ l++++n++i + r+illd+ L+++ +ls++c+vkf+  r+++f r+ww+wllltg++l++++s+K+vg+ft++ +g+ +++
  EEA22196.1 153 DIMWESGYSLPACVLASGLMVFDNAHIGEDRLILLDACLVLSVALSILCYVKFYkqRYNEFGRKWWKWLLLTGISLSCVISTKYVGMFTFVTIGSAVLV 251
                 *******************************************************999***************************************** PP

         PMT 199 elwqllg....dkslllksivkhllaralaliviPvtlylavftvhfwllf 245
                 +lw+ll     + +++l +  +h++ara+ l+++P++lyl++f vhf +l+
  EEA22196.1 252 DLWNLLDikrpRGVMSLFRFSQHFAARAFGLLIVPFFLYLFWFQVHFAILN 302
                 ******865555555555559**************************9885 PP

>> PMT_4TMC  C-terminal four TMM region of protein-O-mannosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.3       0.8   3.6e+03     110     110 ..      68      68 ..      39     118 .. 0.54
   2 ?   -2.7   0.2      0.84   3.7e+03     157     178 ..     186     207 ..     143     221 .. 0.69
   3 ?    0.5   0.7     0.085   3.8e+02     124     177 ..     235     296 ..     229     303 .. 0.75
   4 !  230.9   2.8   2.2e-72   9.9e-69       1     197 [.     540     769 ..     540     770 .. 0.96

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 0.8
    PMT_4TMC 110 y 110
                 y
  EEA22196.1  68 Y 68 
                 1 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 0.84
    PMT_4TMC 157 vklivvvvllvlviavFiffsp 178
                 +  +++v+ ++l+i++++ f +
  EEA22196.1 186 LLDACLVLSVALSILCYVKFYK 207
                 4456666777777777777765 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.085
    PMT_4TMC 124 hYlpAllfailllaalldfllkslkkslkkk.........klvklivvvvllvlviavFiffs 177
                  Y++ + f ++  a+l+d +   l+ ++++          + +++++ ++++ + ++ F+f  
  EEA22196.1 235 KYVGMFTFVTIGSAVLVDLWN-LLDIKRPRGvmslfrfsqHFAARAFGLLIVPFFLYLFWFQV 296
                 588888999999999999994.55544444488999888777778888888888888888755 PP

  == domain 4  score: 230.9 bits;  conditional E-value: 2.2e-72
    PMT_4TMC   1 FlkkflelqkamltsnnalteshpyaSepyeWplllrgisywtkneekkqiyllGNpvlwwlstiallvfvllllalllrrqrgvkdl.....eeeetr 94 
                 F++k+ elq+am+ +nnalt++hpyaSep++Wp+llrg+s+wt+ e+k qiy+lGNp++ww+++++l+vfv++++a++l+ +rg++++     +  ++r
  EEA22196.1 540 FIRKWAELQRAMFFHNNALTSEHPYASEPFQWPFLLRGVSFWTNAETKGQIYFLGNPIGWWFASSLLAVFVGVIGADQLSLRRGIDAIeeiwgPGARSR 638
                 99**************************************************************************************88877667777 PP

    PMT_4TMC  95 llnsglflllgwalhylPfflmgRvlflhhYlpAllfailllaalldfllkslkkslkkk.............................klvklivvvv 164
                 l+ns++fl+l+wa+hy+Pf+lmgR+ flhhYlpA+l+++l++aal++f++ +l+   + k                              +++++++vv
  EEA22196.1 639 LYNSTGFLFLCWAAHYFPFWLMGRQRFLHHYLPAHLASCLVAAALVEFIF-TLDPIAPAKtdykadptgrgrlilgrfrtskerlgrqsLYAGWAATVV 736
                 *************************************************9.55655555579*************************99999******* PP

    PMT_4TMC 165 llvlviavFiffspltyGlpgtseevkklkwls 197
                 +l++vi++F +f+pltyG+ ++ + v+++kwls
  EEA22196.1 737 ILSAVIYSFAYFAPLTYGTALDVDGVNARKWLS 769
                 *******************************96 PP

>> MIR  MIR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.4   0.7   1.3e-21   5.9e-18      12     171 ..     348     500 ..     331     513 .. 0.90

  Alignments for each domain:
  == domain 1  score: 65.4 bits;  conditional E-value: 1.3e-21
         MIR  12 fHshqdeyltiseqqqkqevflritlypsadaanssraLWeievvqkd...awrgglikwgkvyRlkHlaTgryLaseeekksplseseddqkevsayg 107
                  Hsh d+y+    + + +++ +++t yp+ d +n+    W i +       + +g  ik+g+++ l+H+ T   L  ++   spl+ ++++ ++vs+  
  EEA22196.1 348 LHSHDDQYPLRYDDGRISSQGQQVTGYPHNDTNNQ----WQILPSVPFpenDRTGHKIKNGDTVQLRHVSTNTILLTHDV-ASPLMPTNQEFTTVSQEL 441
                 5********9999999999999*************....***98654334477***************************.*******99999***999 PP

         MIR 108 legfegdnDkveifekksttgmksaklvprdsyvrlqHvvtgcwLhstsvklkkekfekvqqkv 171
                 ++g +++    ++fe k ++g+  +++++ +  ++l+Hv t  ++++++++l++++ +  q ++
  EEA22196.1 442 ADGERHS---DTLFEIKIENGKTGQNFRSLSGLFKLIHVPTRVAMWTHTTPLPEWGHK--QAEI 500
                 9888666...99********************************************99..7776 PP

>> PMT_2  Dolichyl-phosphate-mannose-protein mannosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.1   0.00033       1.5      92     121 ..      38      68 ..      33      91 .. 0.85
   2 ?   14.6   3.3   6.2e-06     0.028      30     132 ..     142     252 ..     127     262 .. 0.71
   3 ?    0.2   0.6      0.17   7.6e+02      12      43 ..     264     296 ..     261     303 .. 0.81
   4 ?   -2.5   0.4       1.2   5.3e+03      30      49 ..     648     667 ..     638     690 .. 0.45
   5 ?   -3.9   0.1       3.2   1.4e+04      53      56 ..     737     740 ..     718     753 .. 0.51

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00033
       PMT_2  92 aleknk.lkywllagvlfGlgflsKytaall 121
                 a++ ++ + yw+++ v+ +l+f ++++++ +
  EEA22196.1  38 ATKAPSeWDYWVAMFVMTALAFVTRFWMINY 68 
                 44455579*******************9866 PP

  == domain 2  score: 14.6 bits;  conditional E-value: 6.2e-06
       PMT_2  30 lagvltilllyllarrlfgkraallaalllavvplfvalsa....lftpdaplvllwalalylllrale.......knk.lkywllagvlfGlgflsKy 116
                  +g+lti +++ ++ ++     +l a++l++ +++f +       l+ +da lvl +al++++++++ +       + k +k++ll+g+++   + +Ky
  EEA22196.1 142 TLGSLTIPVVFDIMWESGY---SLPACVLASGLMVFDNAHIgedrLILLDACLVLSVALSILCYVKFYKqrynefgR-KwWKWLLLTGISLSCVISTKY 236
                 5555666666666555433...344444444444333333233447889*******************988777644.4599***************** PP

       PMT_2 117 taallliaallyllis 132
                   ++  +++  ++l++
  EEA22196.1 237 VGMFTFVTIGSAVLVD 252
                 **99999776677766 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.17
       PMT_2  12 lftklfgf.selairlvsalagvltilllylla 43 
                  +++lf f + +a+r +  l++   ++l+++ +
  EEA22196.1 264 GVMSLFRFsQHFAARAFGLLIVPFFLYLFWFQV 296
                 578899888889999999999998888888765 PP

  == domain 4  score: -2.5 bits;  conditional E-value: 1.2
       PMT_2  30 lagvltilllyllarrlfgk 49 
                 l+ +  ++ ++l+ r++f +
  EEA22196.1 648 LCWAAHYFPFWLMGRQRFLH 667
                 34444444444444444432 PP

  == domain 5  score: -3.9 bits;  conditional E-value: 3.2
       PMT_2  53 llaa 56 
                 +l+a
  EEA22196.1 737 ILSA 740
                 1111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (776 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       567  (0.0316247); expected 358.6 (0.02)
Passed bias filter:                      357  (0.0199119); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.30s 00:00:00.93 Elapsed: 00:00:00.45
# Mc/sec: 5179.50
//
Query:       EEA22197.1  [L=379]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.037   14.5   0.0        0.1   13.1   0.0    1.7  1  HTH_26    Cro/C1-type HTH DNA-binding domain


Domain annotation for each model (and alignments):
>> HTH_26  Cro/C1-type HTH DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   5.7e-06       0.1      10      41 ..     344     376 ..     341     377 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 5.7e-06
      HTH_26  10 gi.tkseLargtgisaatlsrlvkgkpervsld 41 
                 +i + ++La++tg+s+a +++l  ++++ +sl+
  EEA22197.1 344 NIkSLYRLAKATGMSRAEFQNLIRNEIDLLSLS 376
                 68899*********************9999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (379 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       663  (0.0369792); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 2715.74
//
Query:       EEA22198.1  [L=501]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.8e-34  116.8  28.9    9.8e-34  116.8  28.9    1.3  2  MFS_1            Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.8  28.9   5.5e-38   9.8e-34       6     352 ..      73     440 ..      68     441 .. 0.83
   2 ?   -4.2   0.3      0.33   5.9e+03     211     221 ..     464     474 ..     449     480 .. 0.42

  Alignments for each domain:
  == domain 1  score: 116.8 bits;  conditional E-value: 5.5e-38
       MFS_1   6 flsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlgagalf 103
                  l+ l+++i+++a    + +dlg+ +  ++  + ++++ ++v++lp    +  +G+r ++ l  ++f+l +l+ +f  + w  +++lrvl G+ +++++
  EEA22198.1  73 SLNLLDSGIISSASVTSMISDLGLEGNRYSVSIFIFTVSSVVFQLPSTIAVRFVGPRIWFALITFCFGLITLCTAF-VQTWrQMIALRVLLGISMSGIY 170
                 5789999999999999999***************************************888888888888577779.67777***************** PP

       MFS_1 104 pagaaliadwfpkeergraigllsagfslGailgpllggllasslg......Wravfyilaivsllafvlfllll...peepperkrkspkeee..... 188
                 p+  +li+ w++++e+ + +++l++g  l  + g ++   l ++ g      Wr+++++ +++++l +v+ ++++   pe++ ++ ++ +++e      
  EEA22198.1 171 PGLTYLISTWYTRKEQQLRFAFLQSGEVLVLATGNIVNYGLNHLDGhrelagWRWMYIVQGLITCLIGVVTYWWMvdfPEKAANSVWFLSEPEIelane 269
                 ******************************************76669**********************999999888555555555555555566666 PP

       MFS_1 189 ........kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgailallagrls.drlgrrrrll 278
                         + + p+++++     + dp l+ + + ++l  ++ ++++++lp++l + +g+s    a++ll+++   +a++ +l++ l+ d++  r + +
  EEA22198.1 270 riradrgdVVPDPFSWKK-VAVNFLDPKLYGFSVLFFLLNLVSTSMSYFLPIILESGMGFS--ENASILLSAPPYYWAVIPVLITSLIgDKFRLRGPAI 365
                 666687888888888888.77777788777777888888889999****************..66666666666666666666666666**88877777 PP

       MFS_1 279 lallllllaalglallavtssavllll.vlvliGfglgfvfpsllalasdlappeeagtasglfntagslggalg 352
                 ++ +l+l+a ++++ l+ ++  ++ ++  +++ G  ++   ++ +++a++ +++ +++t++++++ +++lgg+ g
  EEA22198.1 366 IFNALVLIAGFLMFGLSISHQVTVRYIgTYLTTGAYVSNWAALNAYQANNIVGQWKRATIAAAVTACNGLGGIAG 440
                 7777777777777777777555555552555566666666777778888888********************998 PP

  == domain 2  score: -4.2 bits;  conditional E-value: 0.33
       MFS_1 211 illialllfff 221
                 il+i+++++f+
  EEA22198.1 464 ILMIVIVCGFT 474
                 23333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (501 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       981  (0.0547158); expected 358.6 (0.02)
Passed bias filter:                      507  (0.0282782); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.42
# Mc/sec: 3560.84
//
Query:       EEA22199.1  [L=687]
Description: dynein intermediate chain, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    0.00029   21.6   7.3        5.6    8.0   0.1    5.1  6  WD40        WD domain, G-beta repeat
  ------ inclusion threshold ------
      0.064   13.8   0.3        1.8    9.2   0.7    2.4  2  Kri1        KRI1-like family
      0.076   13.0   1.1        0.2   11.7   1.1    1.7  1  Dynein_IC2  Cytoplasmic dynein 1 intermediate chain 2


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       1.7     1e+04      13      38 .]     302     337 ..     298     337 .. 0.51
   2 !    8.0   0.1   0.00093       5.6       7      38 .]     346     380 ..     338     380 .. 0.82
   3 !    4.8   0.2    0.0095        57       8      37 ..     400     432 ..     392     433 .. 0.71
   4 !    8.0   0.1   0.00095       5.7       7      37 ..     502     539 ..     497     540 .. 0.75
   5 ?   -2.3   0.1       1.7     1e+04      15      38 .]     577     601 ..     572     601 .. 0.58
   6 ?   -0.3   0.0      0.41   2.4e+03      21      36 ..     636     651 ..     627     653 .. 0.80

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 1.7
                 EEEEEEETTSSEEE.EEET.........TSEEEEEE CS
        WD40  13 vtslafspdgawla.sGsd.........DgtvriWd 38 
                 +++l+fsp  + l+ ++           Dg + +W+
  EEA22199.1 302 ISDLSFSPKFPELIlAAYTknptaphepDGLLQVWN 337
                 566666665544322332223444444577777776 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.00093
                 EESS..SSEEEEEEETTSSEEEEEE.TTSEEEEEE CS
        WD40   7 ltGH..ssvtslafspdgawlasGs.dDgtvriWd 38 
                 +  H  s++   +fsp ++ l+ G+ + g v +Wd
  EEA22199.1 346 YVFHstSDILTAKFSPFHPNLIVGGtYSGQVLLWD 380
                 45686566999*********9988548*******9 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.0095
                 ESS.SSEEEEE..EETTSSEEEEEETTSEEEEE CS
        WD40   8 tGH.ssvtsla..fspdgawlasGsdDgtvriW 37 
                  GH  +v+s+a    ++ + ++++s Dg v  W
  EEA22199.1 400 AGHtHPVYSIAiiGTQNAHNILTASTDGVVCGW 432
                 488556****9985555555667777**99766 PP

  == domain 4  score: 8.0 bits;  conditional E-value: 0.00095
                 EESS.SSEEEEE......EETTSSEEEEEETTSEEEEE CS
        WD40   7 ltGH.ssvtsla......fspdgawlasGsdDgtvriW 37 
                 ++GH  +v s a        + g++++s+s D +v++W
  EEA22199.1 502 YRGHaAPVMSTAfhpargPVDFGDLMLSSSLDWSVKLW 539
                 7899777855544477776666788889999******* PP

  == domain 5  score: -2.3 bits;  conditional E-value: 1.7
                 EEEEETTSSEEEEE...ETTSEEEEEE CS
        WD40  15 slafspdgawlasG...sdDgtvriWd 38 
                 + ++sp+ + ++ G   +  g+v +Wd
  EEA22199.1 577 DAKWSPHRPGVF-GlvdG-AGNVEVWD 601
                 555666655554.44323.57788887 PP

  == domain 6  score: -0.3 bits;  conditional E-value: 0.41
                 TSSEEEEEETTSEEEE CS
        WD40  21 dgawlasGsdDgtvri 36 
                 +g+ +a+G+ Dg v +
  EEA22199.1 636 EGRRVATGGLDGVVTV 651
                 56679*******9966 PP

>> Kri1  KRI1-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.7    0.0003       1.8       6      37 ..      10      41 ..       3      66 .. 0.77
   2 ?    1.4   0.0     0.078   4.6e+02      17      60 ..     187     258 ..     173     280 .. 0.68

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0003
        Kri1  6 ekeekkeelkrlkklkreeieeklekikkaag 37
                +k++k +elkr+++l+++e+++  + i  a  
  EEA22199.1 10 AKKAKLAELKRQRELRQKEFNQNRASIGDASE 41
                5889999*******************998876 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.078
        Kri1  17 lkklkreeieeklekikkaag............................eeeaalkeleeeeledlldgdfD 60 
                  ++  r+eiee+l   +++ g                            ++  ++ e +++ +e+ ld+++D
  EEA22199.1 187 IRERIRKEIEEELHASQQVNGngipasssqlryplrtlnddelnavtssNDFLDFVEKSSKVIERALDEEYD 258
                 556667899999999999888888888887777776666665555555544444445555555555555555 PP

>> Dynein_IC2  Cytoplasmic dynein 1 intermediate chain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   1.1   3.3e-05       0.2      19      30 ..     136     147 ..     134     147 .. 0.95

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 3.3e-05
  Dynein_IC2  19 KEtVtYsKeTQT 30 
                 KEtVtYsK  QT
  EEA22199.1 136 KETVTYSKAVQT 147
                 9**********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (687 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       475  (0.0264934); expected 358.6 (0.02)
Passed bias filter:                      344  (0.0191868); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.64u 0.30s 00:00:00.94 Elapsed: 00:00:00.49
# Mc/sec: 4257.53
//
Query:       EEA22200.1  [L=90]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.3e-20   73.6   0.3    1.3e-20   73.5   0.3    1.1  1  ATP-synt_E    ATP synthase E chain
  ------ inclusion threshold ------
       0.12   12.4   2.5       0.23   11.5   2.5    1.5  1  Adhesin_P1_N  Adhesin P1 N-terminal domain


Domain annotation for each model (and alignments):
>> ATP-synt_E  ATP synthase E chain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.5   0.3   1.5e-24   1.3e-20       7      86 ..       3      80 ..       1      90 [] 0.87

  Alignments for each domain:
  == domain 1  score: 73.5 bits;  conditional E-value: 1.5e-24
  ATP-synt_E  7 sPlinvlRysaLalGvvyGakrqrslkseekkeekereleaqekliekakaayakkkqakseakslaegssakiddedp....d 86
                s  +nvlR+saL  Gv+yG ++q+ l+ ++k++e ere++++e+li+kaka+ a+k+++ +      +++ +++d+edp    +
  EEA22200.1  3 SQGVNVLRWSALFGGVFYGLYHQSALNTQAKQAEIEREYKHKESLIAKAKAEWARKNAPAD------SKNGLITDPEDPkfdlE 80
                5689******************************************************999......66777888888865553 PP

>> Adhesin_P1_N  Adhesin P1 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   2.5   2.5e-05      0.23      32      61 ..      26      55 ..      24      60 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 2.5e-05
  Adhesin_P1_N 32 taeeadaKkaeIkaDYnkQakeikaatdeY 61
                  +a +++aK+aeI+ +Y+ +++ i +a +e 
    EEA22200.1 26 SALNTQAKQAEIEREYKHKESLIAKAKAEW 55
                  566899**************9999986665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (90 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       718  (0.0400469); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.49
# Mc/sec: 554.48
//
Query:       EEA22201.1  [L=213]
Description: COP9 signalosome subunit 8 (CsnH), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.7e-27   94.7   0.1    6.6e-27   94.3   0.1    1.2  1  CSN8_PSD8_EIF3K  CSN8/PSMD8/EIF3K family


Domain annotation for each model (and alignments):
>> CSN8_PSD8_EIF3K  CSN8/PSMD8/EIF3K family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.3   0.1   3.7e-31   6.6e-27       5     134 ..      52     181 ..      48     191 .. 0.96

  Alignments for each domain:
  == domain 1  score: 94.3 bits;  conditional E-value: 3.7e-31
  CSN8_PSD8_EIF3K   5 elytniLlkaLtqndladfrlllkrlpaaiqqsdeeiqklltLetlLeeanyakfwstlksddlsadltadvagleelvReeiaklvgkaYesI 98 
                       +y+ +L+++L+ + ++++r+l++r+p+ ++q+d+ iq+ +++ + + +++y k +++l+ +++++ +   v+ +   + e+ ++ +++ YesI
       EEA22201.1  52 VFYSSFLFSHLLIDEIQEARALTQRIPSTLIQNDPVIQHSIAVLRSIYQNKYSKTYALLRGQPWPKPVDIVVQRFDAYYTENSFRNISRIYESI 145
                      689******************************************************************************************* PP

  CSN8_PSD8_EIF3K  99 sadvlaelLglssdeelekfvkevgWeldaatvivp 134
                      +++ +ae+Lgl++ +el +  +++gWe+d+++ ++ 
       EEA22201.1 146 RPEAAAEYLGLQKNAELIDTLVKRGWEWDSDKELFR 181
                      *******************************99886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (213 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       340  (0.0189637); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.29s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1478.14
//
Query:       EEA22202.1  [L=741]
Description: oligosaccharyl transferase subunit (Stt3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   7.4e-147  490.2  36.6   4.1e-142  474.6  34.1    2.1  2  STT3      Oligosaccharyl transferase STT3 subunit


Domain annotation for each model (and alignments):
>> STT3  Oligosaccharyl transferase STT3 subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  474.6  34.1  2.3e-146  4.1e-142       2     488 .]      22     498 ..      21     498 .. 0.96
   2 !   16.1   0.0   2.3e-07    0.0042     447     485 ..     518     557 ..     503     559 .. 0.91

  Alignments for each domain:
  == domain 1  score: 474.6 bits;  conditional E-value: 2.3e-146
                 HHHHHHHHHCCCCCHCC.CCCCCCT--S--SSCHHHHHHHCCCHHHT-C.....CCHHSSEETTSSTTT-EEESTTCCHCCC.CHHHHHHCCHHC.... CS
        STT3   2 lilvifalialvavasrdlFtdedglsylsefDpYYnyRltenllnnGfpGdvvikkknwfdhsqyyPpGsrvdygplivlLamlasaiinhsld.... 96 
                 l +vi+  ia +a+asr lF++++++s+++efDp++n+R+t++l+++Gf     + +  wfd+++++P+G rv++g+l+++L m++s++i+h+l+    
  EEA22202.1  22 LRIVILCTIAAAAIASR-LFSVIRFESIIHEFDPWFNFRATKHLVEHGF-----YSFWDWFDDRTWHPLG-RVTGGTLYPGL-MVTSGVIYHFLRflti 112
                 678999***********.*******************************.....****************.***********.**************** PP

                 .HHHHHHHHCCHHHHHHHHCHHHHHHH.HHHS-CCCHHHHHHHCCC-CCCCCTTSTT--STCCCCHHHHHHHHHHHHHHHHCCSTTCHHHHHHHHHHHH CS
        STT3  97 .vsirevclwlpallgsLlaIpiyflv.relksdiaGllAAlllaiaPgYlsrtvaGfyDtdmfeivlllfvlffflkaiktksnkislaviaaliifl 193
                  v+ir++c++l++++++L+a ++y+l+   ++s+ aGllAA++++i PgY+sr+vaG+yD+++++i+ll+f++f+++ka+k++s  i++ +++al++ +
  EEA22202.1 113 pVDIRNICVLLAPAFSGLTALATYLLTnEMTTSPSAGLLAAAFMGITPGYISRSVAGSYDNEAIAIFLLVFTFFLWIKAVKNGS--IMWGALTALFYGY 209
                 ***************************555789***************************************************..************* PP

                 HHTTSCCGGHHHHCCHHHHHHHHHCTTTS-CCHHHHHHHHHHHHHHH..CCCCCCCTTCHHHSTTTCHHCCCCHHHHHHHHCCCHHC..CCCCCHHCCC CS
        STT3 194 ivlaWggyailiyallllfilalLiigrfelklkiavtfsviiaflviaiivllflgfqvvavseiigalgifgllqlvafgsvvvlvaelkfyqfisl 292
                 +v+aWggy ++i++l++l++++l+ +gr++++l+i++t+++++++l+  +++++f+gf ++++s++++algifgl+q+vaf+++ +   ++  +qf++l
  EEA22202.1 210 MVSAWGGY-VFITNLIPLHVFVLICMGRYSSRLYISYTTWYALGTLA--SMQIPFVGFLPIRSSDHMAALGIFGLIQVVAFVDFIRT--QIPGKQFQTL 303
                 ********.**************************************..**************************************..*********9 PP

                 HHTT.HHHHTT--GGGHHHHHHHHHHHHCCCCCCTS-----TTHHHHHHHHHS---S--CCHHHCCSSSTTTTCCCHHHCHHCCHHCTCHHHHHHHHHH CS
        STT3 293 fqpgilsevlgligevvtalavlglialwlgilyslldleyaklkikiiilvsvwlpvgllaltkglrfliftvPlgiifvgllleflavfvkiysvsq 391
                 + +  +  + g++   +  l++ g+ia+w+g++ysl+d+ yak++i+ii++vs+++p+ + a++++l fli+++P+g++ ++ +l++++vf+ iysv++
  EEA22202.1 304 LTSL-VLLIFGVSFIGLVGLTLSGIIAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTAWPAFFFDLSFLIWLFPAGVYMCFRELRDEHVFIVIYSVLA 401
                 9999.66666777889999999***************************************************************************** PP

                 HHHCCC-SCHCCCCCHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCT.TTTTHHH.TTHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCS CS
        STT3 392 ilfsgvvvillmltllpvlallaavkiskifstykdekeakikvaakavaptksnglkeslew.kantnrdsvvitwwdyghilaveadrpVtfdggs 488
                  +f+gv+v+ lmltl+pv+++ +a+++s++++ty   k+      a ++++ +    ++++   +++t ++     +++ +++l+v++ ++Vt++++s
  EEA22202.1 402 SYFAGVMVR-LMLTLTPVVCVASAIALSYLLDTYLLLKSPTPAKDAPPAKSSDGLRSERGTVYgIQSTFSKVFTAASMSAYLLLFVAHCTWVTSNAYS 498
                 *********.************************987665544444444677777889999999********************************98 PP

  == domain 2  score: 16.1 bits;  conditional E-value: 2.3e-07
                 .TTTTHHH.TTHHHCHHHHHHHHHHHHHHHHHHHHHHHHH CS
        STT3 447 glkeslew.kantnrdsvvitwwdyghilaveadrpVtfd 485
                    e+ +w ++nt++++ +++wwdyg+ +  +adrp+++d
  EEA22202.1 518 DYREAYYWlRQNTEQNAKIMSWWDYGYQIGGMADRPTLVD 557
                 567999********************************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (741 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       665  (0.0370907); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.66u 0.28s 00:00:00.94 Elapsed: 00:00:00.46
# Mc/sec: 4849.46
//
Query:       EEA22203.1  [L=733]
Description: mRNA cleavage and polyadenylation specificity factor complex subunit (Pta1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.7e-71  239.8   0.4    6.8e-71  238.5   0.2    1.8  2  DUF3453    Domain of unknown function (DUF3453)
  ------ inclusion threshold ------
       0.18   10.3   0.4         11    4.4   0.0    2.4  2  Adaptin_N  Adaptin N terminal region


Domain annotation for each model (and alignments):
>> DUF3453  Domain of unknown function (DUF3453)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  238.5   0.2   7.6e-75   6.8e-71       1     224 [.      89     307 ..      89     310 .. 0.93
   2 ?   -3.3   0.0      0.64   5.7e+03     128     162 ..     665     699 ..     653     711 .. 0.74

  Alignments for each domain:
  == domain 1  score: 238.5 bits;  conditional E-value: 7.6e-75
     DUF3453   1 dpavvkkvIqaaasiYplvlrliiknsedsetWekmtalKdeIlrlvdssdndgvrlaaiKFiervilvqtrg.vadrneskeqseislsqvpdnhpil 98 
                 d+av+k+++q+a+s+Yp+v+r+ii +++d+++W+++ta+K++Il+++d+++   vr+++iKF+++v+ +qt+g +ad++   e++e+s+++vp++hp+l
  EEA22203.1  89 DVAVIKSTVQTASSLYPFVFRHIIHHPNDTAMWDQITAIKHNILQRMDTAP-HPVRVCCIKFVQKVVHTQTPGpIADPRR-PERNETSIAIVPRTHPLL 185
                 689************************************************.*********************9999444.567*************** PP

     DUF3453  99 sprkLeaEAkrlLdrlLkvlqeasiltsslviatlnslasiakqRpqfankilqallsfnplkk...pnlpptlsklqvksvektlkvlllnllknsse 194
                 s+++LeaEA++lLdrlL+vlq++ +  + lv+at+n+l +++++Rp +ankil++ll+fnp k    p +p+   ++++ks+e+t++++l+nllk++++
  EEA22203.1 186 SIPNLEAEASGLLDRLLTVLQDD-SDDAILVNATINCLGILIRSRPTIANKILETLLNFNPIKIdhgPLTPT--MRVKIKSMERTTRAVLINLLKRNPN 281
                 ********************986.66777********************************888*9999999..************************* PP

     DUF3453 195 hplqskiqqlleklgallqeiaaviaeetr 224
                 hpl++k+qq++e   +l q+  +++ + ++
  EEA22203.1 282 HPLAGKMQQHME---RLAQNCIEAF-DASS 307
                 ************...8888887777.3333 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 0.64
     DUF3453 128 lviatlnslasiakqRpqfankilqallsfnplkk 162
                  ++ +++ l  ++  Rp   +  l+al+++    +
  EEA22203.1 665 RINLCVQALHYLVMFRPPSREICLNALEEIYNTYE 699
                 57778999999999999999999999999875444 PP

>> Adaptin_N  Adaptin N terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.1    0.0023        21     240     421 ..     185     242 ..      61     265 .. 0.59
   2 ?    4.4   0.0    0.0013        11     241     299 ..     640     699 ..     559     708 .. 0.88

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.0023
                 CG....CSSCHHHHHHHHHCCHCCCCST.HHHCCHHCHHHHHHSSCCTCHHHHHCHHHHHHHHXXTTTTTTTCCCCSXXTTSXHHHHHHHHHHHCCCXX CS
   Adaptin_N 240 lq....ssnnaVlletvnlivelapkne.livlavnaLvrllsskdenlryvaLrtllkivkkepkavqhldlkifllktdddvsirlkaldlllklvd 333
                 l+     + ++ ll    ++ + +++++ l+ + +n+L+ l++                                                        
  EEA22203.1 185 LSipnlEAEASGLLDRLLTVLQDDSDDAiLVNATINCLGILIR-------------------------------------------------------- 227
                 5555554555555555555555333333444445555555555........................................................ PP

                 TTTHHHHHHHHHHHTTSSXXHHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHTTXXHHHHHHHHHHHHHHHHHSTTTSTTCHHHHCC CS
   Adaptin_N 334 esNvkeivkeLkkyvkevadedfksklvkaIgrlaekfatdaewvldvllellslsgesvkdeivevirdliqkvpelheeiiekLae 421
                                                                                           +p+   +i+e+L++
  EEA22203.1 228 -------------------------------------------------------------------------SRPTIANKILETLLN 242
                 .........................................................................555555555555544 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.0013
                 G..CSSCHHHHHHHHHCCHCCCCSTHHHCCHHCHHHHHHSSCCTCHHHHHCHHHHHHHHXX CS
   Adaptin_N 241 q..ssnnaVlletvnlivelapknelivlavnaLvrllsskdenlryvaLrtllkivkkep 299
                 +  s  + V l  +  + +la ++e i l+v+aL+ l+  +++  r + L++l +i  + +
  EEA22203.1 640 RflSEIPEVTLPIIGRVQTLAMDPERINLCVQALHYLVMFRPP-SREICLNALEEIYNTYE 699
                 3556667788888888889999*****************8888.8*********9988874 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (733 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       534  (0.0297841); expected 358.6 (0.02)
Passed bias filter:                      428  (0.0238719); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.66u 0.26s 00:00:00.92 Elapsed: 00:00:00.43
# Mc/sec: 5083.25
//
Query:       EEA22204.1  [L=75]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-06   28.6   0.0    1.1e-06   28.5   0.0    1.1  1  Coiled-coil_56  Coiled-coil domain-containing protein 56


Domain annotation for each model (and alignments):
>> Coiled-coil_56  Coiled-coil domain-containing protein 56
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.5   0.0   6.4e-11   1.1e-06      50      91 ..      30      71 ..      16      75 .] 0.85

  Alignments for each domain:
  == domain 1  score: 28.5 bits;  conditional E-value: 6.4e-11
  Coiled-coil_56 50 rrnlltGlaiGglvlgiygytfysvkqekfldeleeeakaar 91
                     rn ltGl++ g ++g+y +t+ +v qe f d +   a aa 
      EEA22204.1 30 VRNALTGLGLCGFIVGVYAFTIRAVGQEDFSDVVVPSAPAAS 71
                    59*****************************98887777775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (75 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       335  (0.0186848); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.43
# Mc/sec: 522.08
//
Query:       EEA22205.1  [L=710]
Description: hypothetical protein PMAA_059840 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-14   54.3   5.0    1.7e-14   54.3   5.0    2.3  2  Sds3      Sds3-like
  ------ inclusion threshold ------
       0.16   11.4   0.2       0.42   10.0   0.1    1.7  1  DUF1487   Protein of unknown function (DUF1487)


Domain annotation for each model (and alignments):
>> Sds3  Sds3-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -9.3   8.6         2   1.8e+04     147     147 ..     146     146 ..      60     278 .. 0.56
   2 !   54.3   5.0     2e-18   1.7e-14       2     132 ..     306     448 ..     305     614 .. 0.82

  Alignments for each domain:
  == domain 1  score: -9.3 bits;  conditional E-value: 2
        Sds3 147 l 147
                 l
  EEA22205.1 146 L 146
                 0 PP

  == domain 2  score: 54.3 bits;  conditional E-value: 2e-18
        Sds3   2 leklskiessFaelRDklYrerLteLqteltllq..qGthpellrklrdleeerDaeLkrlrlreeyqlkriekefkadiekakqeheklvkllkekly 98 
                 +++l+ +e++Fa lR+k+Y+er++++ +el++l   + thpellr+l+ l++ rD++ +  +   +y+++++ +   ad+ ++++ + + +++++ek  
  EEA22205.1 306 IDALAVLEKEFATLREKIYDERIAKIDRELEQLTspEPTHPELLRQLECLQRHRDKKINYEHTLYQYRMQSLMSRSLADRAQIHSTYFQRIRDTREKHS 404
                 688999***************************833568************************************************************ PP

        Sds3  99 eelekkikrLkeeklllDlanansl...kktrshta.......g 132
                 + ++k+ + ++ ++ + +   a+ +   + +rs++        +
  EEA22205.1 405 TAVSKQFYAIQHDRFKTEELGAHHYipfPTRRSQQIsqqtaynQ 448
                 *************************9995555544432212331 PP

>> DUF1487  Protein of unknown function (DUF1487)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.1   4.7e-05      0.42      41      88 ..     319     366 ..     305     385 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 4.7e-05
     DUF1487  41 veesirdefvervrsklkplseevaeHpsylkalekidelkaktisak 88 
                 ++e+i de + ++ ++l++l +   +Hp  l+ le +++ + k i+ +
  EEA22205.1 319 LREKIYDERIAKIDRELEQLTSPEPTHPELLRQLECLQRHRDKKINYE 366
                 789************************************999999874 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (710 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       859  (0.0479112); expected 358.6 (0.02)
Passed bias filter:                      317  (0.0176809); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.25s 00:00:00.90 Elapsed: 00:00:00.42
# Mc/sec: 5020.70
//
Query:       EEA22206.1  [L=540]
Description: RNA binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.9e-11   43.0   0.0    4.5e-07   29.6   0.0    3.3  3  RRM_1     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom
  ------ inclusion threshold ------
      0.032   14.5   0.0      0.062   13.5   0.0    1.5  1  CHASE4    CHASE4 domain


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.4   0.0    0.0001      0.92      42      69 ..     285     312 ..     271     313 .. 0.92
   2 ?   -1.9   0.0      0.34     3e+03       1      10 [.     329     338 ..     329     342 .. 0.75
   3 !   29.6   0.0     5e-11   4.5e-07      23      64 ..     384     425 ..     381     427 .. 0.96

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0001
                 EEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1  42 afVeFeskedAekAlealngkklggrel 69 
                 a+V + ++ +A+kA  alng+ + gr l
  EEA22206.1 285 AYVVYSTPIAAQKAPGALNGTVVLGRHL 312
                 9***********************9987 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.34
                 EEEESETTTS CS
       RRM_1   1 lfVgnLppdv 10 
                 +fVgnL +  
  EEA22206.1 329 VFVGNLDFVG 338
                 8*****8755 PP

  == domain 3  score: 29.6 bits;  conditional E-value: 5e-11
                 SCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEE CS
       RRM_1  23 Gpiksiklvrd.etgkskgfafVeFeskedAekAlealngkkl 64 
                 G ++s+++vrd +t+  kgfa+V+F+++   e+Al  l+gkk+
  EEA22206.1 384 GNVESVRVVRDqATRVGKGFAYVQFHDENCVEAALL-LDGKKF 425
                 89**********************************.****98 PP

>> CHASE4  CHASE4 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   6.9e-06     0.062      78     123 ..     246     317 ..     199     327 .. 0.63

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 6.9e-06
      CHASE4  78 e.........................s.grsgllkldggpalvaaapIltsegegpsrGtlvfgryldeall 123
                 +                         + ++ + ++l  + ++v ++pI  ++  g  +Gt+v+gr+l+ + +
  EEA22206.1 246 HkiesirfrstaygtekgvprraafaHkETMDSTTLSTNAYVVYSTPIAAQKAPGALNGTVVLGRHLRVDNV 317
                 13333444444455555555555554358899999*************999****************87655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (540 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1470  (0.0819901); expected 358.6 (0.02)
Passed bias filter:                      567  (0.0316247); expected 358.6 (0.02)
Passed Vit filter:                        72  (0.00401584); expected 17.9 (0.001)
Passed Fwd filter:                        18  (0.00100396); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 1.00u 0.41s 00:00:01.41 Elapsed: 00:00:00.60
# Mc/sec: 2697.09
//
Query:       EEA22207.1  [L=341]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (341 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       422  (0.0235373); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.66u 0.32s 00:00:00.98 Elapsed: 00:00:00.56
# Mc/sec: 1829.45
//
Query:       EEA22208.1  [L=169]
Description: hypothetical protein PMAA_059870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (169 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       412  (0.0229795); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.44
# Mc/sec: 1145.11
//
Query:       EEA22209.1  [L=337]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (337 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       600  (0.0334653); expected 358.6 (0.02)
Passed bias filter:                      465  (0.0259356); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.23s 00:00:00.69 Elapsed: 00:00:00.39
# Mc/sec: 2608.35
//
Query:       EEA22210.1  [L=1202]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
  ------ inclusion threshold ------
        7.4    6.6  21.9        1.5    8.9   0.8    4.4  4  Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C


Domain annotation for each model (and alignments):
>> Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0      0.36   6.5e+03      54      90 ..     470     494 ..     462     511 .. 0.44
   2 ?    8.9   0.8   8.2e-05       1.5      15     101 ..     545     626 ..     541     635 .. 0.87
   3 ?    6.5   4.2   0.00045       8.1      18     123 ..     663     770 ..     650     788 .. 0.67
   4 ?    0.4   1.0     0.034   6.1e+02      32      32 ..     844     844 ..     784     905 .. 0.47

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 0.36
  Baculo_PEP_C  54 lksllaeldtrldtlltnLtdalnalqdtlrneLtnl 90 
                   +++++++l++            l +++dt rn+L++ 
    EEA22210.1 470 VEKAMPDLSR-----------MLDSFKDT-RNKLQAR 494
                   3444444443...........22222221.3333333 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 8.2e-05
  Baculo_PEP_C  15 fldLtnvLnairlqnvqilaqlatlldaietqLnalsedlksllaeldtrldtlltnLtdalnalqdtlrneLtnlnsiltnLlssv 101
                    +dL+n+ + i     +i + l t  ++ e+ L++++++l+s +  l+++++++  + +++l + ++  r eL   + +ltnL  ++
    EEA22210.1 545 RVDLSNQQDRI----KNIQGYLDTFRKQNEE-LEQVKSELESEIHTLEKKVEEMEMEHERTLEEAKEHERAELSMQKEELTNLFEEI 626
                   68999999999....7788999998888776.9******************************************99****998776 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.00045
  Baculo_PEP_C  18 LtnvLnairlqnvqilaqlatlldaietqLnalsedlksllaeldtrldtlltnLtdalnalq...dtlrneLtnlnsiltnLlssvtNinstLnnl 111
                   L ++ + +++      a+l+++l+++e   n+l++ ++++  + +++l+t  ++L+++  +l+   ++++++ + +  +  +Ll+  + ++stL+ l
    EEA22210.1 663 LEEAHSNLQTEHDDKHAELERTLADLEAAKNDLQA-VRDSFVSKSEDLETKEKELETTKTELEeklEEVKKAQDDVHYKQEELLATQAELQSTLEEL 758
                   55555555555555566666666666555555443.5555555555777777777777777776667777888888888899999999999999999 PP

  Baculo_PEP_C 112 lqalnnldlgal 123
                   ++  + l+    
    EEA22210.1 759 VTKKAELEAKHA 770
                   988777754443 PP

  == domain 4  score: 0.4 bits;  conditional E-value: 0.034
  Baculo_PEP_C  32 i 32 
                   +
    EEA22210.1 844 L 844
                   1 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1202 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2858  (0.159407); expected 358.6 (0.02)
Passed bias filter:                      571  (0.0318478); expected 358.6 (0.02)
Passed Vit filter:                       214  (0.011936); expected 17.9 (0.001)
Passed Fwd filter:                       108  (0.00602376); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 2.69u 0.41s 00:00:03.10 Elapsed: 00:00:00.69
# Mc/sec: 5221.88
//
Query:       EEA22211.1  [L=171]
Description: NADH-ubiquinone oxidoreductase 178 kDa subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (171 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       401  (0.022366); expected 358.6 (0.02)
Passed bias filter:                      291  (0.0162307); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.57u 0.36s 00:00:00.93 Elapsed: 00:00:00.56
# Mc/sec: 912.68
//
Query:       EEA22212.1  [L=398]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
       0.01   15.6   0.0       0.44   10.3   0.0    2.3  2  Methyltransf_16  Lysine methyltransferase


Domain annotation for each model (and alignments):
>> Methyltransf_16  Lysine methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   2.5e-05      0.44      18      78 ..     131     190 ..     126     220 .. 0.83
   2 ?    2.8   0.0    0.0046        83     120     149 ..     297     326 ..     278     345 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 2.5e-05
  Methyltransf_16  18 grkvWdaavvlvkylekklakelganelsklsvlELGsGtGlvGlavaellpeakviltDl 78 
                      g k W+ ++ l+  l++ ++ +   +e ++++v+ELG Gt +  l++ ++   ++++ tD+
       EEA22212.1 131 GFKTWECSLDLADVLLTSVEIGASVEEGEDVHVIELGCGTAVPSLMLFAK-ILLSLTSTDR 190
                      56789999999999999888889999**************9999988666.3455555555 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.0046
  Methyltransf_16 120 evDlilaaDcvYledslelLvkvLkellkk 149
                      +  lila+  +Y  +sl    +++ +ll++
       EEA22212.1 297 SSTLILASETIYSPSSLGVFSETVLDLLRH 326
                      4579**************999999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (398 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       534  (0.0297841); expected 358.6 (0.02)
Passed bias filter:                      463  (0.0258241); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.48
# Mc/sec: 2499.14
//
Query:       EEA22213.1  [L=419]
Description: cystathionine gamma-lyase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   3.3e-140  467.0   0.0   3.8e-140  466.8   0.0    1.0  1  Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
    1.1e-08   34.7   0.1    1.7e-08   34.0   0.1    1.2  1  Aminotran_1_2    Aminotransferase class I and II
    1.5e-06   27.8   0.3    3.1e-06   26.7   0.3    1.5  1  DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family
    5.9e-06   25.5   0.1    1.2e-05   24.5   0.1    1.4  1  Aminotran_5      Aminotransferase class-V
      0.001   18.4   0.3     0.0027   17.0   0.3    1.8  1  Beta_elim_lyase  Beta-eliminating lyase
  ------ inclusion threshold ------
      0.068   12.0   0.0       0.11   11.3   0.0    1.3  1  GDC-P            Glycine cleavage system P-protein


Domain annotation for each model (and alignments):
>> Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  466.8   0.0  1.3e-143  3.8e-140       2     382 .]      35     410 ..      34     410 .. 0.98

  Alignments for each domain:
  == domain 1  score: 466.8 bits;  conditional E-value: 1.3e-143
                      HHHHHTTTTCHTTTTBSS--B---SBBBESSHHHHCTTCSSS.-SBTTT--HHHHHHHHHHHHHHT-SEEEEESSHHHHHHHHHHTTS-TTEEE CS
  Cys_Met_Meta_PP   2 Tllvhagqekdeqtgavavpiyltstykfkdvdeafageekg.yeYsRsgnptrsvleeriaaLeggeaalavssGmaAiaaailallkaGdei 94 
                      T +vh+g + d++tgav++pi+l++t+ ++     + g+  g yeY+Rs np+r+++ee++aaLe++  ala+ssG a++ a+il+ l aG+++
       EEA22213.1  35 TRAVHSGAHIDPSTGAVIAPISLSTTFAQS-----SVGKPIGnYEYTRSANPNRDHFEEAVAALEHARYALAFSSGSATT-AIILQSLAAGSHV 122
                      899***************************.....78888888*********************************9998.99*********** PP

                      EEESTSSHHHHHHHHHTHHHTTCEEEEESTTSHHHHHHHCCTTEEEEEEESS-TTTT----HHHHHHHHHHTT-EEEEEGTTTHTTTS-GGGGT CS
  Cys_Met_Meta_PP  95 vvsddlYggtqrllkkvlkklgievkfvdtsdleelekaikentklvylEtptnpllkvvDiekiaklakkagvlvvvDntfaspllqrplklg 188
                      v+ +d+Yggt+r+++kv+  +g++v+f+ t ++   e+ +k+ tkl+++E+ptnp+l++vDi++++++a+ +g+lvvvDntf+sp++q+pl++g
       EEA22213.1 123 VSVSDVYGGTHRYFTKVAAAHGVNVTFTPTLEIG-TEAILKPDTKLIWIESPTNPTLSLVDIREVTNIAHRHGILVVVDNTFMSPYIQNPLDYG 215
                      *****************************98776.699******************************************************** PP

                      -SEEEEETTTTTTCSSS--EEEEEESSCHHHHHHHHHHHHHHT-B--HHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHTSTTEEEEE-TTST CS
  Cys_Met_Meta_PP 189 aDivvhSaTKylgGhsdvvaGvivvkgkeelkkelkflqnalGavlspfdawlllrGlkTLslRlerhqenAlkvAefLekhpkvekvyYpglp 282
                      aDivvhS TKy++Ghsdv++Gv++ ++ +elk++l+flqna+Gav spfd+wl +rG+kTL+lR ++  +nA +vA+ Le++p v++v+Ypgl 
       EEA22213.1 216 ADIVVHSVTKYINGHSDVLMGVAAFNS-PELKDRLTFLQNAIGAVPSPFDCWLAHRGMKTLHLRAREVTKNATAVAKALEASPLVKSVNYPGLD 308
                      ************************999.****************************************************************** PP

                      TSTTHHHHHHHSSSG-S..EEEEEESSHHHHHHHHHHC-SSSEECSS-SSSS-EEEETTTTTTTTSCHHHHHHTTS-TTEEEEE--SS-HHHHH CS
  Cys_Met_Meta_PP 283 shpqhelakkqlkgagg..vlsFelkseeekakkfvdnlklfslaeslGgveslielpasmthasipkeereaagvtddliRlsvGiEdvdDli 374
                      shpq  +akkq+++a g  +lsF++++++++a++f++++++f laeslGg+esl e+p smtha ipk++rea gv ddl+Rls+GiEd+dDl 
       EEA22213.1 309 SHPQRYIAKKQHRDAMGggMLSFRIHGGHAAAERFCQKVRVFVLAESLGGIESLCEVPSSMTHAGIPKDQREAVGVFDDLVRLSCGIEDADDLA 402
                      ************9875556*************************************************************************** PP

                      HHHHHHHH CS
  Cys_Met_Meta_PP 375 aDlkqale 382
                      aD+ qale
       EEA22213.1 403 ADVLQALE 410
                      ******96 PP

>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.0   0.1   5.7e-12   1.7e-08      46     213 ..      83     232 ..      72     239 .. 0.76

  Alignments for each domain:
  == domain 1  score: 34.0 bits;  conditional E-value: 5.7e-12
                    HHHHHHHHHHHHCTCTTCHTTGGEGEEEESHHHHHHHHHHHHHHHTTT-EEEEEESS-THHHHHHHHTTSE.EEEEEBEETTTTEE-HHHHHHHHT CS
  Aminotran_1_2  46 lpeleealakflgrseklklkreaavvvgsGagaliealifllklnpgdeilvpdptyasyknilrlsgge.vvryplyseedfhldlealeealk 140
                     + +eea+a + +        r  a+ ++sG+   + +l  l+   +g+ +++ + +y+  ++++    ++  v +       f+ +le   ea+ 
     EEA22213.1  83 RDHFEEAVAALEH-------ARY-ALAFSSGSATTAIILQSLA---AGSHVVSVSDVYGGTHRYFTKVAAAhGVNVT------FTPTLEIGTEAIL 161
                    5679999999999.......555.*********9999999999...6777777777666666665544444344444......4445555555555 PP

                    THHCTTETEEEEEEESS-TTT--B--HHHHHHHHHHHHHTTEEEEEEETTTTCBSSSS.HTHHH..HGGSTTSTT...E CS
  Aminotran_1_2 141 eapegnkktkvilvesphNPtGtvatleeleklldlakkynlllfvDeaYagfvfgsl.davat..ranveeepn...l 213
                    +       tk+i++esp NPt ++ +  e++ +   a+++++l++vD ++   + +++ d+ a   ++ v +++n   +
     EEA22213.1 162 KP-----DTKLIWIESPTNPTLSLVDIREVTNI---AHRHGILVVVDNTFMSPYIQNPlDYGADivVHSVTKYINghsD 232
                    43.....89************************...****************999999877777889999999885554 PP

>> DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.7   0.3     1e-09   3.1e-06      21     144 ..      78     200 ..      62     203 .. 0.82

  Alignments for each domain:
  == domain 1  score: 26.7 bits;  conditional E-value: 1e-09
                      S.SHHHHHHHHHHHHHHT-SEEEEESSHHHHHHHHHHHTTTTTT-EEEEESSS-THHHHHHHHTT-E.EEEE-B-TTTSSB-GGGCGGG--TTE CS
  DegT_DnrJ_EryC1  21 s.gpeveeFEkafaaylgvkhaiavssGtaAlhlaLralgvgpgdeVIvpsltFvatanavlelgak.pvfvDvdpdtynidpaaieaaitert 112
                      s +p+ ++FE+a+aa  ++++a+a+ssG+a+ +++L+ l +g    V+ +s  + +t    +++ a   v v  +  t+ i    +ea + + t
       EEA22213.1  78 SaNPNRDHFEEAVAALEHARYALAFSSGSATTAIILQSLAAG--SHVVSVSDVYGGTHRYFTKVAAAhGVNVTFT-PTLEIG---TEAILKPDT 165
                      368999********************************9998..9*************99999876413444333.344444...566689999 PP

                      EEEE...EB-GGGB---HHHHHHHHHHCT-EEEEE CS
  DegT_DnrJ_EryC1 113 kaIl...pVhlyGqvadmdalkaiaakhglkvieD 144
                      k I    p +     +d+ ++++ia++hg+ v+ D
       EEA22213.1 166 KLIWiesPTNPTLSLVDIREVTNIAHRHGILVVVD 200
                      9996333566777788****************998 PP

>> Aminotran_5  Aminotransferase class-V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.5   0.1     4e-09   1.2e-05      41     202 ..      79     226 ..      56     231 .. 0.83

  Alignments for each domain:
  == domain 1  score: 24.5 bits;  conditional E-value: 4e-09
                  HHHHHHHHHHHHHHHHT-STGGGEEEESSHHHHHHHHHHHCCCC-TTTSEEEEETTSHGGGTHHHHHHHHHHTEEEEEEEBETTSCBEGGGHHHH--T CS
  Aminotran_5  41 atkaveearekvaelinaeseeeiiftsGtteainlvalslarslkpgdeivvteaehhanlvpwqelakrtgakvkvipldeegeldldelekllne 138
                  a+   +  +e va+l +a+  + + f sG++   +++++s    l +g ++v ++  + +++    ++a ++g++v++ p  e g+      e+ l++
   EEA22213.1  79 ANPNRDHFEEAVAALEHAR--YALAFSSGSA-TTAIILQS----LAAGSHVVSVSDVYGGTHRYFTKVAAAHGVNVTFTPTLEIGT------EAILKP 163
                  5555567789999999999..5888888876.44445555....589****999999999999*************9999855554......5689** PP

                  TEEEEEEESBETTTTEB--HHHHHHHHHHTT-EEEEE-TTTTTTS---HHHHTESEEEEETTTT CS
  Aminotran_5 139 ktklvaithvsnvtGtiqpveeigklakkkgalvlvDaaqavghipidvkklgvDflafsghKl 202
                  +tkl+ i    n t  + ++ e++++a+++g+lv+vD + + + i+  + ++g+D+++ s  K+
   EEA22213.1 164 DTKLIWIESPTNPTLSLVDIREVTNIAHRHGILVVVDNTFMSPYIQNPL-DYGADIVVHSVTKY 226
                  *************************************999888888666.68999999998884 PP

>> Beta_elim_lyase  Beta-eliminating lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.3     9e-07    0.0027      30     168 ..      79     201 ..      62     334 .. 0.86

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 9e-07
                      --HHHHHHHHHHHHHTT-SEEEEES-HHHHHHHHHHHH--TTEEEEEETT-HHHHSSTTHHHHCC--EEEEE-EBTTTBE-HHHHHHHS--S-T CS
  Beta_elim_lyase  30 edktvnrLedavaelfgkeaalfvpqGtaAnsillkillqrgeevivtepahihfdetgaiaelagvklrdlknkeaGkmdlekleaaikevga 123
                       +++  ++e+ava+l  + +al + +G a  +i l+ l+   +   v + + ++  + +    +a ++ ++++       +le   +ai +   
       EEA22213.1  79 ANPNRDHFEEAVAALEHARYALAFSSGSATTAIILQSLAAGSH---VVSVSDVYGGTHRYFTKVAAAHGVNVTFTP----TLEIGTEAILK--- 162
                      4667889********************************4333...345677888888888888888888888777....44444445555... PP

                      TS-EEEEEEEESSBTTTTTB---HHHHHHHHHHHHHCT-EEEEEE CS
  Beta_elim_lyase 124 heekiklisltvTnntagGqvvsleelrevaaiakkygiplhlDg 168
                        +++kli ++  +n      +sl  +rev++ia+++gi +++D 
       EEA22213.1 163 --PDTKLIWIESPTNP----TLSLVDIREVTNIAHRHGILVVVDN 201
                      ..579*********95....9**********************96 PP

>> GDC-P  Glycine cleavage system P-protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   3.7e-05      0.11     156     257 ..     121     223 ..      91     227 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 3.7e-05
                 EEEEETTS-HHHHHHHHHHHGGGT-EEEEE-GGG--S-....S-EEEEEEEES.-TTSB----HHHHHHHHHTT-EEEEEE-TTGGGTB--HHHHT-SE CS
       GDC-P 156 kvvvdkkvhpqtlevlktrakglgieivevdlteekvtd.kekevagvlvqyp.nteGriedlkelvekakkkkslvvvaadllaLtllkpPgelgaDi 252
                 +vv  ++v+  t +     a   g+++  +++ e +++   + ++  + +  p n + ++ d++e+++ a+++ +lvvv    ++   ++ P ++gaDi
  EEA22213.1 121 HVVSVSDVYGGTHRYFTKVAAAHGVNVTFTPTLEIGTEAiLKPDTKLIWIESPtNPTLSLVDIREVTNIAHRHGILVVVDNTFMSPY-IQNPLDYGADI 218
                 4555677788888888888888888888888777777664567777777777724466899******************99999965.689******** PP

                 EEEE- CS
       GDC-P 253 vvGsa 257
                 vv s 
  EEA22213.1 219 VVHSV 223
                 *9775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (419 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       479  (0.0267165); expected 358.6 (0.02)
Passed bias filter:                      427  (0.0238162); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.43
# Mc/sec: 2897.42
//
Query:       EEA22214.1  [L=194]
Description: DNA-directed RNA polymerase III subunit 22.9 kDa, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.5e-35  121.5   0.3    5.6e-35  120.4   0.3    1.6  1  RNA_pol_Rbc25  RNA polymerase III subunit Rpc25
    1.1e-14   54.6   0.0    1.6e-14   54.0   0.0    1.3  1  SHS2_Rpb7-N    SHS2 domain found in N terminus of Rpb7p/Rpc25


Domain annotation for each model (and alignments):
>> RNA_pol_Rbc25  RNA polymerase III subunit Rpc25
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  120.4   0.3   6.2e-39   5.6e-35       1     129 []      79     193 ..      79     193 .. 0.97

  Alignments for each domain:
  == domain 1  score: 120.4 bits;  conditional E-value: 6.2e-39
                    -STTSEEEEEEEEEETTCEEEEBTTBSEEEEECCCCSTTEEEECCCTCEEEEESSSEEEEE-TTSEEEEEEEEEEE-------HHHHHCHHHCCTS CS
  RNA_pol_Rbc25   1 PfvgevltgkiksstregikvslgffddifvpkelLfepsefdeeeqawvweveeeeelyldvgeeirfrveeeifvdvkpkspkeaeleeeease 96 
                    Pf+ge+l gki s+++eg+k++l+ff di vp+ lLf++s+fd +e++w+we+  e++ y+d+ge +rfrve+e+++d++p+ p++          
     EEA22214.1  79 PFKGEILLGKIASASEEGLKINLEFFGDITVPAALLFDGSRFDLAENIWIWET-GENTYYYDIGEIVRFRVESEEWHDQRPTGPDRV--------- 164
                    9****************************************************.999***************************954......... PP

                    -SS--SSTTS--S-SCEEEEEB-STTTCECGCC CS
  RNA_pol_Rbc25  97 eeaeeeeeekekkspyevlgsiqedGlGlvsWw 129
                        e ++++e+k+py++ +s+  +GlGlvsWw
     EEA22214.1 165 ----EAQTASENKPPYSIRASMMMEGLGLVSWW 193
                    ....45788899********************* PP

>> SHS2_Rpb7-N  SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.0   0.0   1.8e-18   1.6e-14       2      70 .]       9      77 ..       8      77 .. 0.98

  Alignments for each domain:
  == domain 1  score: 54.0 bits;  conditional E-value: 1.8e-18
                 EEEEE-GGGTTSTHHHHHHHHHHHHHTTBEETTTEEEEEEEEEEEECCEEE-TTTSSEEEEEEEEEEEE CS
  SHS2_Rpb7-N  2 dtvrlePsylgstledallerllekyegkvvpslGvivavldiaeysegkvlggsGsvyvrVtfralvF 70
                 d v++ P+++++    a+++ ++eky +kv++++G+++  +d++++s+g + +g+G v v+Vtfr++vF
   EEA22214.1  9 DLVQIRPEDFSKFSAVAIEDNINEKYANKVIQKIGLCIGFYDLLKSSDGLIGHGTGLVNVNVTFRLIVF 77
                 89*********99999****************************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (194 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       368  (0.0205254); expected 358.6 (0.02)
Passed bias filter:                      356  (0.0198561); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.40u 0.27s 00:00:00.67 Elapsed: 00:00:00.41
# Mc/sec: 1415.44
//
Query:       EEA22215.1  [L=603]
Description: CCCH zinc finger protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.4e-13   49.7   7.9    2.4e-13   49.7   7.9    2.4  2  NUFIP1         Nuclear fragile X mental retardation-interacti
    1.2e-06   28.2   5.9    2.1e-06   27.5   5.9    1.4  1  zf-CCCH        Zinc finger C-x8-C-x5-C-x3-H type (and similar
    2.8e-05   24.0   6.8    2.8e-05   24.0   6.8    1.8  2  zf_CCCH_4      Zinc finger domain
    8.6e-05   22.2   6.3    8.6e-05   22.2   6.3    1.6  2  zf-CCCH_4      CCCH-type zinc finger
  ------ inclusion threshold ------
      0.043   14.5   0.0      0.043   14.5   0.0    2.5  2  Torus          Torus domain
       0.55   10.8   4.3       0.97   10.0   4.3    1.4  1  zf-CCCH_2      RNA-binding, Nab2-type zinc finger
        1.7    8.6  20.0        4.1    7.4  20.0    1.6  1  DUF2514        Protein of unknown function (DUF2514)


Domain annotation for each model (and alignments):
>> NUFIP1  Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.7   7.9   9.2e-17   2.4e-13      10      53 .]     309     352 ..     304     352 .. 0.94
   2 ?   -6.0   4.1         7   1.8e+04      43      51 ..     363     369 ..     355     381 .. 0.52

  Alignments for each domain:
  == domain 1  score: 49.7 bits;  conditional E-value: 9.2e-17
      NUFIP1  10 gtsitleTpeeIakWreERkKnyPtkaniekkkkkeeekkkrge 53 
                 g ++tl++  +I+ W+eERkK++Pt+a+ie+kkk +ee+kk++e
  EEA22215.1 309 GRTSTLNNTTDIQSWIEERKKRFPTQARIEEKKKTQEEAKKQKE 352
                 67789************************************987 PP

  == domain 2  score: -6.0 bits;  conditional E-value: 7
      NUFIP1  43 kkeeekkkr 51 
                 ++ +e+  r
  EEA22215.1 363 QELKEQ--R 369
                 222222..2 PP

>> zf-CCCH  Zinc finger C-x8-C-x5-C-x3-H type (and similar)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.5   5.9   8.2e-10   2.1e-06       3      26 ..     498     521 ..     496     522 .. 0.91

  Alignments for each domain:
  == domain 1  score: 27.5 bits;  conditional E-value: 8.2e-10
                 CHCBCHHHHHS--TTGGG-SSBSC CS
     zf-CCCH   3 telCrffmrtGyCkyGdrCkFaHg 26 
                  ++Cr+f+r+G C++G+ C+++H 
  EEA22215.1 498 SKPCRDFQRRGKCPRGSHCRYSHE 521
                 579********************5 PP

>> zf_CCCH_4  Zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.2       1.8   4.6e+03       2       8 ..      96     102 ..      96     102 .. 0.88
   2 !   24.0   6.8   1.1e-08   2.8e-05       1      19 []     501     520 ..     501     520 .. 1.00

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 1.8
   zf_CCCH_4   2 kfflqGt 8  
                 k++++G+
  EEA22215.1  96 KYYQNGS 102
                 8***996 PP

  == domain 2  score: 24.0 bits;  conditional E-value: 1.1e-08
   zf_CCCH_4   1 Ckfflq.GtCkkGdkCrFaH 19 
                 C+ f++ G+C++G++Cr++H
  EEA22215.1 501 CRDFQRrGKCPRGSHCRYSH 520
                 ******************** PP

>> zf-CCCH_4  CCCH-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.1       3.4   8.6e+03       4      10 ..      96     102 ..      96     102 .. 0.87
   2 !   22.2   6.3   3.4e-08   8.6e-05       1      22 []     499     521 ..     499     521 .. 0.96

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 3.4
   zf-CCCH_4   4 pyfakGs 10 
                 +y+++Gs
  EEA22215.1  96 KYYQNGS 102
                 89**996 PP

  == domain 2  score: 22.2 bits;  conditional E-value: 3.4e-08
   zf-CCCH_4   1 rlCpyfa.kGsCrfGdnCrFsHd 22 
                 ++C+ f+ +G+C  G++Cr+sH+
  EEA22215.1 499 KPCRDFQrRGKCPRGSHCRYSHE 521
                 79********************7 PP

>> Torus  Torus domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   3.6       3.5   8.9e+03      31      59 ..     355     382 ..     324     397 .. 0.48
   2 ?   14.5   0.0   1.7e-05     0.043      51      93 ..     480     522 ..     439     533 .. 0.68

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 3.5
                 SS----S-THHHHS-----S----HHHH- CS
       Torus  31 ynkwsgeekekkkkskekaktrcnikkds 59 
                  ++ + +++++ k+++e+a+ + + kk+ 
  EEA22215.1 355 REEAR-RKQQELKEQREQARSQAQEKKEM 382
                 22222.22333334444455555555544 PP

  == domain 2  score: 14.5 bits;  conditional E-value: 1.7e-05
                 ----HHHH----HHHHSTT--B-HHH.HHT--SSGGG-SSB-S- CS
       Torus  51 trcnikkdsGytkadkekesyfClfF.arGlCakGkkCeylHrl 93 
                 +r  +++     +++++ +s  C  F  rG C++G++C+y H+ 
  EEA22215.1 480 QRQGPERVPAPPREQTK-RSKPCRDFqRRGKCPRGSHCRYSHEP 522
                 55555555555555544.44556555168*************83 PP

>> zf-CCCH_2  RNA-binding, Nab2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   4.3   0.00038      0.97       1      17 [.     500     520 ..     500     520 .. 0.99

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00038
   zf-CCCH_2   1 pCrffpn...C.tnpkCpFaH 17 
                 pCr+f     C ++  C+++H
  EEA22215.1 500 PCRDFQRrgkCpRGSHCRYSH 520
                 9******************** PP

>> DUF2514  Protein of unknown function (DUF2514)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4  20.0    0.0016       4.1      27     102 ..     335     412 ..     326     432 .. 0.66

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0016
     DUF2514  27 aewekrwadrdaedsqakviaeeaaReeeqrrkaaaekavkdaqekaaaAr...adavgaaaaadrLrqeaakLaaaks 102
                 a  e+++  ++++ +++k  + e+aR ++q+ k+ +e+a+++aqek+++ +   ++a++a+a+a++Lr+++ k ++  +
  EEA22215.1 335 ARIEEKKKTQEEA-KKQKELQREEARRKQQELKEQREQARSQAQEKKEMGSdpmDAALKAKAKAEKLRKKLLKEERRLQ 412
                 4444444444444.4445556677888888999999**********99875222799***********98766533222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (603 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2905  (0.162028); expected 358.6 (0.02)
Passed bias filter:                      797  (0.0444531); expected 358.6 (0.02)
Passed Vit filter:                       218  (0.0121591); expected 17.9 (0.001)
Passed Fwd filter:                        48  (0.00267723); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 1.16u 0.40s 00:00:01.56 Elapsed: 00:00:00.51
# Mc/sec: 3566.24
//
Query:       EEA22216.1  [L=224]
Description: GPI anchored protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.2e-21   75.9   0.2    3.2e-21   75.9   0.2    3.0  2  GPI-anchored    Ser-Thr-rich glycosyl-phosphatidyl-inositol-a
  ------ inclusion threshold ------
      0.048   12.9  18.7      0.057   12.6  18.7    1.1  1  SOG2            RAM signalling pathway protein
       0.18   11.7   6.6       0.18   11.7   6.6    1.1  1  SPX             SPX domain
        1.7    8.5   3.3          2    8.2   3.3    1.1  1  RIFIN           Rifin
        2.4    6.9  14.6          3    6.6  14.6    1.1  1  Apt1            Golgi-body localisation protein domain
        2.6    7.4   4.0        2.9    7.2   4.0    1.1  1  Plasmodium_Vir  Plasmodium vivax Vir protein


Domain annotation for each model (and alignments):
>> GPI-anchored  Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.9   0.2   1.1e-24   3.2e-21       1      93 []      27     116 ..      27     116 .. 0.98
   2 ?  -12.4  18.1         6   1.8e+04      27      49 ..     153     175 ..     119     208 .. 0.45

  Alignments for each domain:
  == domain 1  score: 75.9 bits;  conditional E-value: 1.1e-24
  GPI-anchored   1 tsPssgevvtagkpvtitWkdsgtdpgtvtlvLcagssnnlksvktiasgiknsdgsytwtvpaslesggaYflqivsesnegiynySdrFti 93 
                   +sP+++ v++ag+++t+tWk+  t+pg+vtl L +gs + +++   +a++i+n  gs+ w+vp +++++ +Yf++i+++++++ +nyS+rF i
    EEA22216.1  27 SSPGANVVFEAGTTTTLTWKP--TTPGPVTLRLQWGSVAGPNDGVVLAASITNI-GSFVWQVPFNIPQQPNYFVRISDDKDPNFVNYSPRFAI 116
                   58*******************..9*****************************9.************************************87 PP

  == domain 2  score: -12.4 bits;  conditional E-value: 6
  GPI-anchored  27 gtvtlvLcagssnnlksvktias 49 
                   ++ + ++++ ss++  + +t a+
    EEA22216.1 153 SSSSTTMVTSSSTSAVPSTTSAT 175
                   22333333333333333333332 PP

>> SOG2  RAM signalling pathway protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6  18.7   1.9e-05     0.057     287     356 ..     124     194 ..      67     210 .. 0.50

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.9e-05
        SOG2 287 gstspp.galsrqslsttgststltsssksrsssrsntnasastprslattpappasaesf..astltasrin 356
                 ++ts++  ++s++s s+t+s+st+tsss+s+ss+++ t  s+st++  +tt+a+++sa+s+  a ++t+ +++
  EEA22216.1 124 STTSASaTSTSASSSSSTSSSSTTTSSSSSSSSTTMVT--SSSTSAVPSTTSATTTSAASTtsAASKTSATTS 194
                 11111111222222233334444444444444444433..222333333333322233222122222222222 PP

>> SPX  SPX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   6.6   6.2e-05      0.18      76     169 ..     125     189 ..      36     207 .. 0.51

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 6.2e-05
         SPX  76 gnsaadasssepkdeaeslprrsplsrssrssssygglvssppsansssssddssesnpadssssssssesesssssspsllrrlfsesesree 169
                 ++sa+ +s s+                        ++++s+++s+ ++sss++ss+    +sss+s  +++ s++++s  ++ +       ++ 
  EEA22216.1 125 TTSASATSTSA------------------------SSSSSTSSSSTTTSSSSSSSSTTMVTSSSTSAVPSTTSATTTSAASTTSA-----ASKT 189
                 11111111111........................11111111111111111111111111111111111111111111111111.....1111 PP

>> RIFIN  Rifin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   3.3   0.00067         2     205     264 ..     130     194 ..      89     218 .. 0.41

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.00067
       RIFIN 205 l....klkkskaaltsakekekkeasskekikkkvekivekaekkaaaaaa.eaaaeataeaeka 264
                 +    ++++s++  +s+++++++++ss+++++++++++v +++++++++aa +++a+ +++a+++
  EEA22216.1 130 AtstsASSSSSTSSSSTTTSSSSSSSSTTMVTSSSTSAVPSTTSATTTSAAsTTSAASKTSATTS 194
                 11111111111111222222222222222222222222222222222222212222222222222 PP

>> Apt1  Golgi-body localisation protein domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6  14.6     0.001         3     320     379 ..     126     190 ..      95     207 .. 0.40

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.001
        Apt1 320 sdeesessssssssssssassssssssrssslelrlkpt........sstssssssessssssskkrs 379
                 ++ + +s+s+sssss+ss+s+++ssss+sss ++    t        s+ts +++s+ s++s ++k+s
  EEA22216.1 126 TSASATSTSASSSSSTSSSSTTTSSSSSSSSTTMV---TssstsavpSTTSATTTSAASTTSAASKTS 190
                 11111111111122222222222222222222222...111112222333333333333333333333 PP

>> Plasmodium_Vir  Plasmodium vivax Vir protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   4.0   0.00097       2.9     212     295 ..     122     195 ..      90     224 .] 0.49

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.00097
  Plasmodium_Vir 212 keaeeklkqekaaeapellnkekaeqgksekslgseslssekpearkgveeqlvhaltsassgtgndaspesiansssslesvs 295
                     ++++++ +++++++++ ++++ ++  ++s++     s+ss+       v + + +a++s++s t+++a+    a s++s ++++
      EEA22216.1 122 STSTTSASATSTSASSSSSTSSSSTTTSSSS-----SSSST-----TMVTSSSTSAVPSTTSATTTSAASTTSAASKTSATTSP 195
                     3333333322222222222211111111111.....11111.....11223344555555555555555555555555444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (224 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1787  (0.0996709); expected 358.6 (0.02)
Passed bias filter:                      626  (0.0349155); expected 358.6 (0.02)
Passed Vit filter:                       227  (0.0126611); expected 17.9 (0.001)
Passed Fwd filter:                        47  (0.00262145); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.77u 0.32s 00:00:01.09 Elapsed: 00:00:00.48
# Mc/sec: 1417.46
//
Query:       EEA22217.1  [L=1520]
Description: ABC multidrug transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.2e-51  173.4   0.1    1.6e-27   96.7   0.1    2.5  2  ABC_tran         ABC transporter
    3.4e-26   92.5  36.1    1.4e-23   84.0  15.5    2.8  3  ABC_membrane     ABC transporter transmembrane region
    6.9e-09   35.5   4.2      0.018   14.5   0.1    4.0  4  SMC_N            RecF/RecN/SMC N terminal domain
    3.3e-07   30.4   3.7      0.049   13.4   0.0    4.1  3  AAA_21           AAA domain, putative AbiEii toxin, Type IV T
    3.5e-06   26.7   0.6      0.041   13.6   0.0    2.8  2  AAA_29           P-loop containing region of AAA domain
    1.2e-05   25.8   0.1      0.034   14.5   0.0    2.6  2  AAA_16           AAA ATPase domain
    1.2e-05   25.2   0.2     0.0061   16.5   0.0    2.6  2  RsgA_GTPase      RsgA GTPase
    1.3e-05   25.8   0.8      0.053   14.0   0.1    2.4  2  AAA_23           AAA domain
    1.6e-05   24.1   0.1     0.0068   15.5   0.0    2.4  2  T2SSE            Type II/IV secretion system protein
    3.9e-05   23.7   0.5       0.34   11.0   0.0    3.1  2  MMR_HSR1         50S ribosome-binding GTPase
    5.2e-05   22.5   0.7     0.0092   15.2   0.0    2.7  2  NB-ARC           NB-ARC domain
    9.3e-05   22.7   0.9        0.2   11.9   0.0    3.0  2  AAA_22           AAA domain
    0.00047   20.6   0.1       0.23   11.9   0.0    3.3  2  AAA              ATPase family associated with various cellul
     0.0029   18.0   0.4       0.46   10.9   0.0    3.2  2  RNA_helicase     RNA helicase
     0.0035   16.9   0.1       0.74    9.3   0.0    2.5  2  AAA_7            P-loop containing dynein motor region
     0.0041   16.9   0.1       0.88    9.2   0.0    2.4  2  AAA_15           AAA ATPase domain
     0.0062   16.9   0.2        2.2    8.6   0.0    2.6  2  AAA_19           AAA domain
     0.0081   15.8   0.0       0.46   10.0   0.0    2.5  2  AAA_25           AAA domain
     0.0087   16.1   0.2       0.87    9.6   0.0    2.5  2  Dynamin_N        Dynamin family
  ------ inclusion threshold ------
      0.014   15.2   0.2          2    8.1   0.0    3.0  2  AAA_30           AAA domain
      0.014   14.6   0.0       0.94    8.7   0.0    2.4  2  Zeta_toxin       Zeta toxin
      0.015   15.2   0.1       0.27   11.1   0.0    2.4  2  ATPase_2         ATPase domain predominantly from Archaea
      0.024   15.2   0.0        4.3    7.9   0.0    2.5  2  AAA_18           AAA domain
      0.028   13.6   0.1        5.5    6.1   0.0    2.3  2  DUF815           Protein of unknown function (DUF815)
      0.034   14.1   0.0      0.095   12.6   0.0    1.7  1  Rad17            Rad17 P-loop domain
      0.039   13.9   0.9        5.6    6.8   0.1    2.6  2  NTPase_1         NTPase
      0.042   12.7   0.5       0.17   10.7   0.0    1.9  2  Adeno_IVa2       Adenovirus IVa2 protein
      0.045   13.8   0.1       0.21   11.6   0.0    2.2  1  AAA_14           AAA domain
      0.051   13.8   0.2         36    4.6   0.0    3.3  3  Roc              Ras of Complex, Roc, domain of DAPkinase
      0.057   13.6   0.6        1.4    9.1   0.0    3.0  3  AAA_33           AAA domain
      0.061   12.9   1.3       0.88    9.1   0.1    2.5  2  cobW             CobW/HypB/UreG, nucleotide-binding domain
      0.079   12.7   4.3         19    4.9   0.0    3.6  3  IstB_IS21        IstB-like ATP binding protein
      0.082   11.9   0.2        2.6    6.9   0.1    2.4  2  MeaB             Methylmalonyl Co-A mutase-associated GTPase 
        0.1   12.3   1.2        6.2    6.5   0.1    2.9  3  AAA_24           AAA domain
       0.11   12.2   0.1        1.7    8.3   0.0    2.4  2  Viral_helicase1  Viral (Superfamily 1) RNA helicase
       0.11   12.2   0.0       0.65    9.7   0.0    2.1  2  AAA_11           AAA domain
       0.14   12.1   0.7        2.5    8.0   0.0    2.5  2  NACHT            NACHT domain
       0.17   11.6   0.3        1.3    8.7   0.0    2.3  2  PduV-EutP        Ethanolamine utilisation - propanediol utili
       0.18   11.9   2.1       0.63   10.1   0.4    2.3  2  DUF87            Helicase HerA, central domain
        0.3    9.8   1.6        1.2    7.8   0.1    2.5  3  ABC_ATPase       Predicted ATPase of the ABC class


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.4   0.0   2.7e-23   1.2e-20       1     136 [.     650     785 ..     650     786 .. 0.76
   2 !   96.7   0.1   3.6e-30   1.6e-27       1     137 []    1252    1397 ..    1252    1397 .. 0.91

  Alignments for each domain:
  == domain 1  score: 74.4 bits;  conditional E-value: 2.7e-23
                 EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.....HHHTC.......... CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxx.......... RF
    ABC_tran   1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren.....esdee.......... 84 
                 lk +++++ e+++  ivG+ G+GKStLlk+++g+  p  G++ +  +++             ++ q++ + +++ +r++     e de+          
  EEA22217.1 650 LKSITMSVPESKISMIVGPVGCGKSTLLKAILGEIPPMHGSVYMATDQVA------------YCDQTAWHVNDT-IRNSviaasEFDEQwystvlqaca 735
                 7899**************************************55555555............555554444444.444444444222222222233333 PP

                 HHHHHHHSTTGGTTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  85 iekalsklglkelkdtvvksspssLSgGqkqrvalarallkkpkllllDEpt 136
                 +++ l++l + +  +t ++s++  LSgGq qr+alara+  k+kl++lD+p 
  EEA22217.1 736 LHEDLRQLPQGD--QTMIGSKGVALSGGQCQRIALARAVYAKRKLVILDDPI 785
                 777777777777..99999********************************7 PP

  == domain 2  score: 96.7 bits;  conditional E-value: 3.6e-30
                  EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH......HHHTCHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxx RF
    ABC_tran    1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren......esdeeiekalsk 91  
                  lk+++l+++ gek++i G++G+GKS+L+ ++ ++++   G+i++dg dl+++++++ r++i  ++q+p+l +++ vr n      + d++i++al++
  EEA22217.1 1252 LKKIDLSIRSGEKIGICGRTGSGKSSLVLAIFRMVELSGGSITIDGIDLSTIPRQEIRARITGVSQDPFLIQGS-VRLNadpngtATDDQITDALRS 1347
                  789***********************************************************************.999999****99999*****99 PP

                  STTGG....TTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                  xxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran   92 lglke....lkdtvvksspssLSgGqkqrvalarallkkpkllllDEpta 137 
                  + l      +    v+ +  +LS+Gq q  +lara+l+++++l+lDE+t+
  EEA22217.1 1348 VHLLSvveeKGGLDVDVEELHLSQGQMQLFCLARAMLRHSSILILDEATS 1397
                  99999443322333444559****************************96 PP

>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3  10.8   2.6e-05     0.012      13     271 ..     285     544 ..     274     547 .. 0.83
   2 ?   -0.2   0.0       1.4   6.4e+02     216     248 ..     529     561 ..     523     566 .. 0.83
   3 !   84.0  15.5   3.1e-26   1.4e-23       3     272 ..     918    1183 ..     915    1187 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 2.6e-05
                   HHHHHHHHHHHHHHHHHHSS...TCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHHHHSCHHHHHHHHHH CS
  ABC_membrane  13 vlsplfplvlgrildtlldk...gdpetealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsffdtnsvGellsrltn 106
                   +l++ +pl+++r +   +d+   ++++      ++ +++l++++++i++  +++l +     ++  l ++l +k   +  s  d  ++ +l ++++ 
    EEA22217.1 285 ALNFSQPLLINRAVYLSVDSvtpWTTHV--GYGLIGAYILVYVGSAIAMGQYQHLAYRSITMVRGGLISMLTRKTTDL--SVRDVDPAVSL-TLMSA 376
                   6788888888888877776533355555..888888999999999999999999999999999999999999998766..88888888777.9**** PP

                   HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHTTTHHHHH CS
  ABC_membrane 107 dvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirtVkafgreeyfl 203
                   dv+++ +g+++ + ++     + v+++++   lg +  lv +++++  ++ s++   +++  + +  +a++++ s +  +l  ++ +k+ g  +   
    EEA22217.1 377 DVERIVQGWQTMHEMWANLAEIGVAIFLLEGQLGIS-CLVPVGVSIFSLFASIIALNFVMARQARWLEAIERRISATSAMLGSMKGIKITGLKNVLF 472
                   ***********************************9.5*********************************************************** PP

                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHTT...SSTHHHHHHHHHHHHHHH CS
  ABC_membrane 204 ekfekaleeakkagikkaianglligitqllgllsyalal.wfGttlvisg...elsvgdlvvflslfailf 271
                   + ++  + +++++++   ++  +++gi+++ + ++ ++++ +f t+   +g   +l+   + + ls+fa+++
    EEA22217.1 473 KSIHTLRIDELNISKGFRRLLIWNMGIAYISQIFAPIITFaVFVTVSHNRGddvALNTARVYTALSIFALMT 544
                   *********999988888788888887777777777777544555555555645666666666666666665 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 1.4
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane 216 agikkaianglligitqllgllsyalalwfGtt 248
                   ++ ++ +a +++  +t+ +++l+++la+++G+ 
    EEA22217.1 529 NTARVYTALSIFALMTDPITTLVMSLAAFVGSI 561
                   556778889999999999999999999999986 PP

  == domain 3  score: 84.0 bits;  conditional E-value: 3.1e-26
                    HHHHHHHHHHHHHHHHHHHHHHHHHHHHSSTCCHH..HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHHHHHHHCSTHHHHHH CS
  ABC_membrane    3 liillailagvlsplfplvlgrildtlldkgdpet..ealnvysllllllglaqfilallqsyllnv.tgerlskrlrrklfkkilrqpmsffdt 94  
                    ++i+l  ++g++  +  ++ + ++++    ++ ++  e++ +y+ ++++lg + +i+  ++ + +++ +  +   r ++ l++ +l++ +sff +
    EEA22217.1  918 IVIFLVCISGFV--FCISFPSIWVKWWAA-SNVQYpyEKSGYYMGIYAMLGGLALITLCISCWQFIItMVPKSGERFHSTLLNTVLSAKTSFFAS 1009
                    444444444443..344445555555554.333334567************************9966377899********************** PP

                    SCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT CS
  ABC_membrane   95 nsvGellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsg 189 
                    +++G  l+r++ d++ ++  l+   +  +  l+++++   ++ + +++ ++   ++l+ ++++++++ +++++l+  + +a a+++s ++E lsg
    EEA22217.1 1010 TDTGVTLNRFSQDLQLIDMELPVAALNTIATLILCIAQTTLIGVASPYTAISFPIVLIALYFIQKYYLRTSRQLRFMDLEAKAPLYSQFTECLSG 1104
                    *********************************************************************************************** PP

                    HHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSTHHHHHHHHHHHHHHHH CS
  ABC_membrane  190 irtVkafgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttlvisgelsvgdlvvflslfailfg 272 
                    + t++afg+++++++k  + le+ ++  +    ++++l  +++l++  + ++ + + + l   g +s g   v ++lf+i+++
    EEA22217.1 1105 LVTIRAFGWQKAMENKSRELLERSQRPFYLLFAVQRWLTLVLDLVVAGIATILIILVVELR--GSISAGY--VGVALFNIIQF 1183
                    *********************************************9999999988888887..9999999..66666666654 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.9   0.0   0.00024      0.11      23      48 ..     659     681 ..     650     686 .. 0.83
   2 ?   -0.6   0.0       1.7   7.5e+02     136     184 ..     757     801 ..     705     823 .. 0.72
   3 !    7.1   0.2    0.0075       3.4      28      48 ..    1266    1285 ..    1253    1298 .. 0.84
   4 !   14.5   0.1   4.1e-05     0.018     136     208 ..    1368    1436 ..    1303    1442 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00024
                 TSSEEEEEESTTSSHHHHHHHHHHHC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  23 sksftaivGpNGSGKsnlldAilFvL 48 
                 ++++++ivGp G+GKs ll Ai   L
  EEA22217.1 659 ESKISMIVGPVGCGKSTLLKAI---L 681
                 56799****************9...4 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 1.7
                 CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 136 lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellk 184
                 +LSgG+ + +ala       + ++ l++lD+  + LD +  + + + l 
  EEA22217.1 757 ALSGGQCQRIALA----RAVYAKRKLVILDDPISGLDTATENHIWHSLM 801
                 7999998766654....44567778999999999999998888777665 PP

  == domain 3  score: 7.1 bits;  conditional E-value: 0.0075
                  EEEESTTSSHHHHHHHHHHHC CS
                  xxxxxxxxxxxxxxxxxxxxx RF
       SMC_N   28 aivGpNGSGKsnlldAilFvL 48  
                   i G+ GSGKs+l+ Ai F +
  EEA22217.1 1266 GICGRTGSGKSSLVLAI-FRM 1285
                  699**************.766 PP

  == domain 4  score: 14.5 bits;  conditional E-value: 4.1e-05
                  CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC-SCE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  136 lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQfivislreemlekadkl 208 
                   LS G+ +L      +A  + + +++ +lDe  ++ D k  +++ ++++ek +n  ++ ++++ +++ + dk+
  EEA22217.1 1368 HLSQGQMQLFC----LARAMLRHSSILILDEATSNVDSKTDEIMQRVIREKFSNHTILAVAHKLDTILDFDKV 1436
                  79999999965....567799*****************************************99988877765 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.0   0.00011     0.049       2      20 ..     663     681 ..     662     692 .. 0.88
   2 ?    6.3   0.1     0.016       7.2       3      35 ..    1266    1292 ..    1265    1325 .. 0.68
   3 !    8.9   0.1    0.0026       1.2     196     268 ..    1331    1397 ..    1299    1426 .. 0.74

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 0.00011
      AAA_21   2 nvliGpNgsGKSnLLdald 20 
                  +++Gp g+GKS+LL+a+ 
  EEA22217.1 663 SMIVGPVGCGKSTLLKAIL 681
                 68***************94 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.016
      AAA_21    3 vliGpNgsGKSnLLdaldllarldrdvegltde 35  
                  ++ G+ gsGKS+L  a+  +      ve ++ +
  EEA22217.1 1266 GICGRTGSGKSSLVLAIFRM------VELSGGS 1292
                  689**************444......3333332 PP

  == domain 3  score: 8.9 bits;  conditional E-value: 0.0026
      AAA_21  196 eielsdlgegeeliasvderlrergvvflengdgqelparelSdGtkrllalltallralkkgsllliDEpEn 268 
                  +++ +++++++ +  ++ ++l    vv ++ g + ++   +lS+G+ +l++l+ a+lr     s+l++DE  +
  EEA22217.1 1331 DPNGTATDDQITDALRSVHLL---SVVEEKGGLDVDVEELHLSQGQMQLFCLARAMLRHS---SILILDEATS 1397
                  444455555555555555554...667777777777777777***************966...*******555 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.6   0.0   9.2e-05     0.041      17      42 ..     655     680 ..     650     687 .. 0.83
   2 !   10.1   0.1    0.0011      0.51      20      42 ..    1260    1282 ..    1252    1286 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 9.2e-05
      AAA_29  17 ieidlkgatlltGpsGsGKSTllDAi 42 
                 +++ ++ + +++Gp G GKSTll Ai
  EEA22217.1 655 MSVPESKISMIVGPVGCGKSTLLKAI 680
                 555555699**************997 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.0011
      AAA_29   20 dlkg.atlltGpsGsGKSTllDAi 42  
                  +  g  + + G++GsGKS+l+ Ai
  EEA22217.1 1260 RS-GeKIGICGRTGSGKSSLVLAI 1282
                  43.347889***********9776 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.0   7.5e-05     0.034      24      88 ..     658     746 ..     647     793 .. 0.63
   2 !    8.4   0.0    0.0059       2.6      27     103 ..    1265    1339 ..    1252    1421 .. 0.57

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 7.5e-05
      AAA_16  24 p..elvllsGesGvGKsslvrellralekd.........ggiflrgkcdqlesa...................ipysalaqalareellrqllde 88 
                 p   + +++G+ G+GKs+l++++l ++                  + cdq   a                     ys+++qa+a +e lrql + 
  EEA22217.1 658 PesKISMIVGPVGCGKSTLLKAILGEIPPMhgsvymatdQ----VAYCDQT--AwhvndtirnsviaasefdeQWYSTVLQACALHEDLRQLPQG 746
                 4447889*****************9999995433333330....3333333..122223333333333333333445555555555555555554 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0059
      AAA_16   27 vllsGesGvGKsslvrellralekdggiflrgkcdqlesaipysalaqalareellrqlldeaesaeleawreklee 103 
                  + + G  G+GKsslv +++r +e + g  ++ +  +l s ip++ +   ++  +    l + +   ++++  ++ ++
  EEA22217.1 1265 IGICGRTGSGKSSLVLAIFRMVELS-GGSITIDGIDL-STIPRQEIRARITGVSQDPFLIQGSVRLNADPNGTATDD 1339
                  557799*************988877.44555555555.346665555555454444444444433334433333333 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   1.4e-05    0.0061      51     123 ..     606     684 ..     596     708 .. 0.72
   2 ?    5.9   0.1     0.024        11     100     125 ..    1263    1288 ..    1246    1296 .. 0.75

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 1.4e-05
                  EEEE-GGG--HHHHHHHHHHHHHHTTSEEEE--T.....TTHTTHHHHHHHCTT.SEEEEECSTTSSHHHHHHHHCTT- CS
  RsgA_GTPase  51 ivlnKiDlleeeeeleelkeelealgyevllvsa.....ktkegleelkellkd.ktsvlvGqSGvGKStLinallpel 123
                  i+ n +Dl++++ + ++ +++l++ ++ vl  s      +++  l++++  + + k+s++vG+ G GKStL++a+l+e 
   EEA22217.1 606 IMTNEADLIKNNGTKTSRSSTLTSRDVIVLQNSDfgwdpEKEPLLKSITMSVPEsKISMIVGPVGCGKSTLLKAILGEI 684
                  6677777777777666666666666666655443111114555677788777777********************9985 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.024
                   SEEEEECSTTSSHHHHHHHHCTT--- CS
  RsgA_GTPase  100 ktsvlvGqSGvGKStLinallpelel 125 
                   + + ++G +G GKS+L+ a+    el
   EEA22217.1 1263 EKIGICGRTGSGKSSLVLAIFRMVEL 1288
                   66679***********9888766555 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.0   0.1   0.00012     0.053      18      39 ..     659     680 ..     650     682 .. 0.90
   2 !    9.8   0.1    0.0023         1      22      39 ..    1265    1282 ..    1252    1286 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 0.00012
      AAA_23  18 skgltlItGpNGaGKTTildAi 39 
                 ++++  I+Gp G+GK+T+l Ai
  EEA22217.1 659 ESKISMIVGPVGCGKSTLLKAI 680
                 678999***************9 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.0023
      AAA_23   22 tlItGpNGaGKTTildAi 39  
                    I+G +G+GK++++ Ai
  EEA22217.1 1265 IGICGRTGSGKSSLVLAI 1282
                  57************9998 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   1.5e-05    0.0068     114     171 ..     646     702 ..     593     752 .. 0.78
   2 ?    6.0   0.0     0.012       5.2     116     156 ..    1249    1289 ..    1231    1299 .. 0.80

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1.5e-05
       T2SSE 114 lkekiaevlrkavrerglilvsGgTgsGKttllyallkeinksderivtvEDpvEiql 171
                   e + + +  +v e ++ ++ G+ g GK+tll a+l ei+  +  + ++ D v +  
  EEA22217.1 646 K-EPLLKSITMSVPESKISMIVGPVGCGKSTLLKAILGEIPPMHGSVYMATDQVAYCD 702
                 3.45566677888999999999*******************99999999988876654 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.012
       T2SSE  116 ekiaevlrkavrerglilvsGgTgsGKttllyallkeinks 156 
                  e i + +  ++r+   i + G TgsGK+ l+ a+  +++ s
  EEA22217.1 1249 EPILKKIDLSIRSGEKIGICGRTGSGKSSLVLAIFRMVELS 1289
                  5677778889999999**************99999888755 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.0   0.00076      0.34       3      23 ..     664     684 ..     663     712 .. 0.77
   2 !    9.4   0.0    0.0024       1.1       1      21 [.    1264    1284 ..    1264    1338 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00076
                 EEEESTTSSHHHHHHHHHTST CS
    MMR_HSR1   3 aivGrpNvGKStLinaltgek 23 
                 +ivG    GKStL++a++ge 
  EEA22217.1 664 MIVGPVGCGKSTLLKAILGEI 684
                 69****************984 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.0024
                  EEEEEESTTSSHHHHHHHHHT CS
    MMR_HSR1    1 evaivGrpNvGKStLinaltg 21  
                  +++i Gr+ +GKS+L+ a+++
  EEA22217.1 1264 KIGICGRTGSGKSSLVLAIFR 1284
                  699*************99986 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   2.1e-05    0.0092      15     111 ..     655     783 ..     644     821 .. 0.79
   2 ?    4.8   0.3      0.03        13      23      44 ..    1265    1286 ..    1249    1408 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 2.1e-05
                 TTTSCSEEEEEEESTTSSHHHHHHHHCCSHCCCCC.CBTEEEEE.................EEESXXHHHHHHHXXHHHHHCCCTTSSSS-STTS.... CS
      NB-ARC  15 kdelqslvvalvGmgGvGKttlakqilnksdeveg.rFdsvawv.................vvsktdkseeiletilkeLslseddleekeeves.... 91 
                 +  ++s +  +vG  G+GK+tl+k il +   ++g  +    +v                 v++ +   e+   t+l+   l+ +dl + +++++    
  EEA22217.1 655 MSVPESKISMIVGPVGCGKSTLLKAILGEIPPMHGsVYMATDQVaycdqtawhvndtirnsVIAASEFDEQWYSTVLQACALH-EDLRQLPQGDQtmig 752
                 5556777999*******************998888778666666555999999999999987777777788888888887777.555555555556888 PP

                 ...........HHHHHHHHCCCTTEEEEEEE CS
      NB-ARC  92 ...........lkrklvrlLltkrfllvlDD 111
                                l r+   kr l++lDD
  EEA22217.1 753 skgvalsggqcQRIALARAVYAKRKLVILDD 783
                 8889999998777788999999999999999 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.03
                  EEEEESTTSSHHHHHHHHCCSH CS
      NB-ARC   23 valvGmgGvGKttlakqilnks 44  
                  +++ G+ G+GK+ l+  i++  
  EEA22217.1 1265 IGICGRTGSGKSSLVLAIFRMV 1286
                  89***************99974 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.9   0.0   0.00045       0.2       6      27 ..     661     682 ..     658     711 .. 0.87
   2 !    7.6   0.5      0.01       4.5      10     104 ..    1267    1400 ..    1260    1431 .. 0.58

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00045
      AAA_22   6 gilvvtGesGtGKTtllrrlle 27 
                 +i +++G++G+GK+tll+ +l 
  EEA22217.1 661 KISMIVGPVGCGKSTLLKAILG 682
                 6789**************9875 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.01
      AAA_22   10 vtGesGtGKTtllrrlleqldeeakaee.........................erpevv..fvtlpsst..sskdl.lrellralglelka...... 70  
                  ++G +G+GK+ l+  +++  +                                ++p ++  +v l+++   + +d   ++ lr ++l          
  EEA22217.1 1267 ICGRTGSGKSSLVLAIFRMVELSG---GsitidgidlstiprqeiraritgvsQDPFLIqgSVRLNADPngTATDDqITDALRSVHL---Lsvveek 1357
                  8************99999975433...134477888888888888877777766666667755555555224444334444444443...2344666 PP

      AAA_22   71 .........erlsseell.ealeqalrarav...ielliiDEaqh.lr 104 
                                 +l   +++  + ara+    ++li+DEa   ++
  EEA22217.1 1358 ggldvdveeL-----HLSqGQMQLFCLARAMlrhSSILILDEATSnVD 1400
                  7777544331.....222233333333333344445788888776565 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.9   0.0   0.00052      0.23       2      23 ..     664     685 ..     663     724 .. 0.69
   2 ?    4.4   0.1      0.11        49       3      33 ..    1267    1307 ..    1265    1432 .. 0.51

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00052
                 EEESSTTSSHHHHHHHHHHHHT CS
         AAA   2 llyGppGtGKTllakavakelg 23 
                 +++Gp G+GK++l ka+  e+ 
  EEA22217.1 664 MIVGPVGCGKSTLLKAILGEIP 685
                 689***************9963 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.11
                  EESSTTSSHHHHHHHHHHHH..........THEEEEEETTT CS
         AAA    3 lyGppGtGKTllakavakel..........gvefleisgse 33  
                  ++G  G GK++l+ a+ + +          g+++ +i   e
  EEA22217.1 1267 ICGRTGSGKSSLVLAIFRMVelsggsitidGIDLSTIPRQE 1307
                  57899999999999999986332222222222222222222 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.9   0.0     0.001      0.46       2      63 ..     664     745 ..     663     753 .. 0.65
   2 ?    3.4   0.1      0.21        96       3      23 ..    1267    1287 ..    1265    1300 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.001
  RNA_helicase   2 wlyGpsgeGKStlakeLakallkkl....................klkkkdsvysrnpeddfwdgYtgqevvvidDfgqvkd 63 
                   +++Gp g+GKStl k +  ++                        +++ ++sv++ +  d+ w++   q++ + +D+ q ++
    EEA22217.1 664 MIVGPVGCGKSTLLKAILGEIPPMHgsvymatdqvaycdqtawhvNDTIRNSVIAASEFDEQWYSTVLQACALHEDLRQLPQ 745
                   689*************666655222555666666666666666665555566666666666666666666666666666655 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.21
  RNA_helicase    3 lyGpsgeGKStlakeLakall 23  
                    ++G++g GKS+l+  + + ++
    EEA22217.1 1267 ICGRTGSGKSSLVLAIFRMVE 1287
                    89**********988777665 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.0    0.0017      0.74      29      59 ..     656     686 ..     650     711 .. 0.85
   2 ?    4.7   0.0     0.041        18      27      56 ..    1256    1285 ..    1253    1301 .. 0.85

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.0017
       AAA_7  29 llknkkpvllvGptGtGKtviikdllkkldk 59 
                  + ++k  ++vGp+G+GK++++k +l ++++
  EEA22217.1 656 SVPESKISMIVGPVGCGKSTLLKAILGEIPP 686
                 56677889****************9998875 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.041
       AAA_7   27 elllknkkpvllvGptGtGKtviikdllkk 56  
                  +l ++++ ++ ++G tG+GK++++  +++ 
  EEA22217.1 1256 DLSIRSGEKIGICGRTGSGKSSLVLAIFRM 1285
                  67788999999***********99887665 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.2   0.0     0.002      0.88      23      43 ..     659     680 ..     649     715 .. 0.82
   2 ?    5.0   0.1     0.038        17      22      50 ..    1258    1289 ..    1252    1316 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.002
      AAA_15  23 ee.ltvliGkNnsGKSsileal 43 
                 e+ ++ ++G+ ++GKS++l+a+
  EEA22217.1 659 ESkISMIVGPVGCGKSTLLKAI 680
                 3349*****************9 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.038
      AAA_15   22 see...ltvliGkNnsGKSsilealdlFlnnk 50  
                  s        ++G+ +sGKSs++ a+  + + +
  EEA22217.1 1258 SIRsgeKIGICGRTGSGKSSLVLAIFRMVELS 1289
                  3333357889**************97776655 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.6   0.0     0.005       2.2       9      78 ..     659     788 ..     651     851 .. 0.62
   2 ?    5.5   0.1     0.045        20      13     129 ..    1265    1414 ..    1258    1430 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.005
      AAA_19   9 kekvllvtaGpGtGKTrvlkhivallvelggvkpeeillvaftgrAakelrerlaalgae..............atTiHrlal................ 77 
                 ++k+ +++++ G+GK+++lk+i+ ++  ++g        va+  + a  +++ +++   +              a+      l                
  EEA22217.1 659 ESKISMIVGPVGCGKSTLLKAILGEIPPMHGSVYMATDQVAYCDQTAWHVNDTIRNSVIAasefdeqwystvlqACA-----Lhedlrqlpqgdqtmig 752
                 57889999******************999999999999999999999999998866555544555555444444333.....13333445555555555 PP

      AAA_19  78 ...................................l 78 
                                                    l
  EEA22217.1 753 skgvalsggqcqrialaravyakrklvilddpisgL 788
                 555555555555555555555555555555555551 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.045
      AAA_19   13 llvtaGpGtGKTrvlkhivallvelggvkpeeillvaftgrAakelrerlaalgae..........................atTiHrlalldfddl 83  
                  + + +  G+GK+ ++ +i ++++  gg    +i  + +     +e+r r++++ ++                           + +H l++++ ++ 
  EEA22217.1 1265 IGICGRTGSGKSSLVLAIFRMVELSGGS--ITIDGIDLSTIPRQEIRARITGVSQDpfliqgsvrlnadpngtatddqitdaLRSVHLLSVVEEKGG 1359
                  6688889999999999999998887765..5566666666667899999988888899999999999999999999999888889999999777777 PP

      AAA_19   84 ltealelle........eaeeekklqeeellivDEf.qdvdelqyrLlkallgek 129 
                  l+  +e l+            +  l++  +li DE+ ++vd    ++++++  ek
  EEA22217.1 1360 LDVDVEELHlsqgqmqlFCLARAMLRHSSILILDEAtSNVDSKTDEIMQRVIREK 1414
                  77777777777777767444567887777******64678877777777776544 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.0   0.0     0.001      0.46       7      50 ..     635     677 ..     629     684 .. 0.86
   2 ?    2.9   0.0      0.16        72      29      53 ..    1258    1282 ..    1234    1294 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.001
      AAA_25   7 lsavsvadlaapppprrwlvkgllpagelallaGapgtGKttla 50 
                 l++++++++  + p ++ + + + p+ ++++++G+ g+GK+tl+
  EEA22217.1 635 LQNSDFGWDPEKEPLLKSITMSV-PESKISMIVGPVGCGKSTLL 677
                 56778888888888888888888.******************97 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.16
      AAA_25   29 llpagelallaGapgtGKttlaldl 53  
                   ++ ge + ++G++g+GK+ l+l +
  EEA22217.1 1258 SIRSGEKIGICGRTGSGKSSLVLAI 1282
                  4677899999***********9976 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.0     0.002      0.87       3      22 ..     665     684 ..     664     725 .. 0.86
   2 ?    3.5   0.5      0.15        67       1      18 [.    1265    1282 ..    1265    1292 .. 0.89

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.002
                 EEEBTTTTHHHHHHHHHTS- CS
   Dynamin_N   3 vvGsqSsGKSSvlnaLlged 22 
                 +vG +  GKS++l a+lge 
  EEA22217.1 665 IVGPVGCGKSTLLKAILGEI 684
                 89****************85 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.15
                  EEEEEBTTTTHHHHHHHH CS
   Dynamin_N    1 iavvGsqSsGKSSvlnaL 18  
                  i ++G + sGKSS++ a+
  EEA22217.1 1265 IGICGRTGSGKSSLVLAI 1282
                  789***********8776 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.0    0.0044         2      18      39 ..     660     681 ..     649     750 .. 0.85
   2 ?    3.2   0.1      0.14        64      23      47 ..    1267    1310 ..    1256    1422 .. 0.48

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0044
      AAA_30  18 drvavltGpAGtGKttalkalr 39 
                  ++++++Gp G GK+t+lka+ 
  EEA22217.1 660 SKISMIVGPVGCGKSTLLKAIL 681
                 4599***************994 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.14
      AAA_30   23 ltGpAGtGKttalkalreaweaag...................g 47  
                  + G+ G+GK+ ++ a+ +++e +g                    
  EEA22217.1 1267 ICGRTGSGKSSLVLAIFRMVELSGgsitidgidlstiprqeirA 1310
                  67889999999999998888888635444444433333333331 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.0    0.0021      0.94      15      54 ..     659     698 ..     647     733 .. 0.85
   2 ?    3.2   0.0       0.1        47      21      53 ..    1267    1299 ..    1260    1310 .. 0.86

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0021
  Zeta_toxin  15 rPklillgGqpGAGKselaellkdelerqgnvvrldpDdl 54 
                 + k+ +++G  G+GKs+l++++  e+ +  + v + +D++
  EEA22217.1 659 ESKISMIVGPVGCGKSTLLKAILGEIPPMHGSVYMATDQV 698
                 55778899******************99999998888875 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.1
  Zeta_toxin   21 lgGqpGAGKselaellkdelerqgnvvrldpDd 53  
                  + G +G+GKs+l  ++ + +e  g+ +++d+ d
  EEA22217.1 1267 ICGRTGSGKSSLVLAIFRMVELSGGSITIDGID 1299
                  6799***********999999999999998755 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00061      0.27      20      42 ..     660     682 ..     647     706 .. 0.85
   2 ?    1.1   0.0       0.7   3.1e+02      25      44 ..    1267    1286 ..    1252    1414 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00061
    ATPase_2  20 neiyfiYGpegsGKtaLlkeiie 42 
                 ++i +i Gp g+GK++Llk i+ 
  EEA22217.1 660 SKISMIVGPVGCGKSTLLKAILG 682
                 68999**************9975 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.7
    ATPase_2   25 iYGpegsGKtaLlkeiienl 44  
                  i G+ gsGK++L+  i    
  EEA22217.1 1267 ICGRTGSGKSSLVLAIFRMV 1286
                  88**********99887655 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   0.0    0.0095       4.3       2      59 ..     664     725 ..     664     781 .. 0.64
   2 ?    4.6   0.0       0.1        45       1      21 [.    1265    1285 ..    1265    1352 .. 0.81

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0095
      AAA_18   2 lltGtpGvGKttlakeLskrlgf....gvnlrdvakenglllevdpe..aldeskrldedkldk 59 
                 ++ G+ G+GK+tl k++    ++    g +++ + +  ++  + ++    +++s ++  +++++
  EEA22217.1 664 MIVGPVGCGKSTLLKAILG--EIppmhGSVYMATDQVAYCDQTAWHVndTIRNSVIAASEFDEQ 725
                 589************9933..3333354443333333333333333333344444444555444 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.1
      AAA_18    1 IlltGtpGvGKttlakeLskr 21  
                  I+++G  G+GK++l  ++ ++
  EEA22217.1 1265 IGICGRTGSGKSSLVLAIFRM 1285
                  89***********98777555 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.0     0.012       5.5      56      77 ..     663     684 ..     622     695 .. 0.81
   2 ?    4.8   0.1     0.029        13      58      81 ..    1267    1290 ..    1258    1316 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.012
      DUF815  56 vLLwGarGtGKSslvkallney 77 
                  +++G  G+GKS+l+ka+l e+
  EEA22217.1 663 SMIVGPVGCGKSTLLKAILGEI 684
                 5889**************9876 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.029
      DUF815   58 LwGarGtGKSslvkallneyaeeg 81  
                  + G  G+GKSslv a+++ ++ +g
  EEA22217.1 1267 ICGRTGSGKSSLVLAIFRMVELSG 1290
                  789************998776655 PP

>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   0.00021     0.095      40      65 ..     657     680 ..     646     726 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 0.00021
       Rad17  40 LesrkkriLLisGPsGCgkstvvkvL 65 
                 ++  + +i +i GP GCgkst +k +
  EEA22217.1 657 VP--ESKISMIVGPVGCGKSTLLKAI 680
                 33..44799**************965 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.0     0.054        24       3      23 ..     664     684 ..     663     691 .. 0.88
   2 ?    6.8   0.1     0.012       5.6       1      42 [.    1264    1307 ..    1264    1316 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.054
                 EEE--TTSSHHHHHHHHHHHH CS
    NTPase_1   3 fiTGppGvGKtTlvkkvlell 23 
                 +i Gp G GK+Tl+k +l ++
  EEA22217.1 664 MIVGPVGCGKSTLLKAILGEI 684
                 588************998765 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.012
                  EEEEE--TTSSHHHHHHHHHHHH...G..GGEEEEEEEEE---- CS
    NTPase_1    1 kvfiTGppGvGKtTlvkkvlellkssg..vkvgGfyteevregg 42  
                  k+ i G+ G+GK+ lv  + ++++ sg  ++++G+  + + +++
  EEA22217.1 1264 KIGICGRTGSGKSSLVLAIFRMVELSGgsITIDGIDLSTIPRQE 1307
                  5889*****************99877523667787766666555 PP

>> Adeno_IVa2  Adenovirus IVa2 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00037      0.17      86     124 ..     659     695 ..     645     712 .. 0.72
   2 ?   -0.7   0.1       1.1   4.7e+02      90     107 ..    1266    1282 ..    1257    1290 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00037
  Adeno_IVa2  86 qPviGviyGPtGsGksqllrnlissklisPiPetvifit 124
                 +  i +i GP G+Gks ll++++    i P+   v++ t
  EEA22217.1 659 ESKISMIVGPVGCGKSTLLKAILGE--IPPMHGSVYMAT 695
                 45699****************9975..566666665555 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 1.1
  Adeno_IVa2   90 GviyGPtGsGksqllrnl 107 
                  G i G tGsGks l+ ++
  EEA22217.1 1266 G-ICGRTGSGKSSLVLAI 1282
                  4.68**********9776 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   0.00048      0.21       2      44 ..     660     701 ..     659     736 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00048
      AAA_14   2 rkilvitGaRrvGKTtllkqlikellvkkesilyinldderdk 44 
                 +ki +i+G+  +GK+tllk ++ e   +    +y++ d+  + 
  EEA22217.1 660 SKISMIVGPVGCGKSTLLKAILGEIP-PMHGSVYMATDQVAYC 701
                 68999****************98877.7778888888886663 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.0     0.088        39       3      23 ..     664     684 ..     661     721 .. 0.67
   2 ?    4.6   0.0     0.081        36       1      21 [.    1264    1284 ..    1264    1313 .. 0.77
   3 ?    0.1   0.0         2     9e+02      65     119 ..    1372    1428 ..    1370    1429 .. 0.64

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.088
                 EEESSTTSSHHHHHHCHCT-C CS
         Roc   3 vlvGdsgvGKtsllkrfvedk 23 
                 ++vG  g GK++llk ++ + 
  EEA22217.1 664 MIVGPVGCGKSTLLKAILGEI 684
                 79*************998653 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.081
                  EEEEESSTTSSHHHHHHCHCT CS
         Roc    1 KvvlvGdsgvGKtsllkrfve 21  
                  K+ ++G +g+GK+sl+  + +
  EEA22217.1 1264 KIGICGRTGSGKSSLVLAIFR 1284
                  8999***********987654 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 2
                  SGGCTTTT-HHHHCTSCEEEEEEE.GHHHHCHHHHHHH.HHHHCSSS-EEEEEE-TT CS
         Roc   65 Gqerfrslhplylreaalailvyd.srssenlkeWlke.lkkvagkspvilvgnkiD 119 
                  Gq +   l++  lr+++++il    s+ +++ +e ++  ++++ ++  ++ v+ k+D
  EEA22217.1 1372 GQMQLFCLARAMLRHSSILILDEAtSNVDSKTDEIMQRvIREKFSNHTILAVAHKLD 1428
                  555566666666777777666544244456666666551577788999999999998 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.0    0.0031       1.4       3      25 ..     664     690 ..     662     785 .. 0.76
   2 ?    0.9   0.1         1   4.6e+02       4      16 ..    1267    1279 ..    1265    1295 .. 0.87
   3 ?   -1.5   0.0       5.5   2.5e+03      24      41 ..    1450    1473 ..    1444    1505 .. 0.62

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0031
      AAA_33   3 llvGlpGsGKstlaerllkklg....a 25 
                 ++vG+ G+GKstl++ +l + +     
  EEA22217.1 664 MIVGPVGCGKSTLLKAILGEIPpmhgS 690
                 89*************999887744433 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 1
      AAA_33    4 lvGlpGsGKstla 16  
                  ++G  GsGKs l+
  EEA22217.1 1267 ICGRTGSGKSSLV 1279
                  69********997 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 5.5
      AAA_33   24 gavllssdtlrrrlfg......td 41  
                  +++lls+d++++rl+       ++
  EEA22217.1 1450 PYTLLSTDSAFNRLYTysmadeDE 1473
                  699**********99866543322 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.1     0.002      0.88       3      21 ..     663     681 ..     661     695 .. 0.87
   2 ?    1.9   0.2      0.32   1.4e+02       3      21 ..    1265    1283 ..    1263    1294 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.002
                 EEEEESTTCCHHHHHHHHH CS
        cobW   3 tvltGflGsGKTtLlnhll 21 
                 ++++G++G GK+tLl+++l
  EEA22217.1 663 SMIVGPVGCGKSTLLKAIL 681
                 789*************998 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.32
                  EEEEESTTCCHHHHHHHHH CS
        cobW    3 tvltGflGsGKTtLlnhll 21  
                  ++++G  GsGK++L+ ++ 
  EEA22217.1 1265 IGICGRTGSGKSSLVLAIF 1283
                  6799**********99886 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0      0.43   1.9e+02      50      67 ..     663     680 ..     649     693 .. 0.86
   2 ?    4.9   0.0     0.043        19      44      67 ..    1259    1282 ..    1252    1293 .. 0.89
   3 ?    4.9   0.3     0.043        19      87     145 ..    1364    1422 ..    1361    1435 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.43
   IstB_IS21  50 ivllGpsGvGKshlaial 67 
                  +++Gp G GKs l  a+
  EEA22217.1 663 SMIVGPVGCGKSTLLKAI 680
                 579*********998876 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.043
   IstB_IS21   44 iekkenivllGpsGvGKshlaial 67  
                  i++ e i ++G +G GKs l  a+
  EEA22217.1 1259 IRSGEKIGICGRTGSGKSSLVLAI 1282
                  67889999************9997 PP

  == domain 3  score: 4.9 bits;  conditional E-value: 0.043
   IstB_IS21   87 veelkrarrdgklaralkrllkv.dllilDdlgllpldqaeaellfeviekryerrsiii 145 
                  veel++ +++ +l   ++++l+  ++lilD+  + ++d++  e + +vi +++ +++i+ 
  EEA22217.1 1364 VEELHLSQGQMQLFCLARAMLRHsSILILDEA-TSNVDSKTDEIMQRVIREKFSNHTILA 1422
                  577888888888888888777654999**995.6899***************99988865 PP

>> MeaB  Methylmalonyl Co-A mutase-associated GTPase MeaB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.18        81      13      50 ..     644     681 ..     632     688 .. 0.88
   2 ?    6.9   0.1    0.0058       2.6      17      66 ..    1250    1299 ..    1240    1305 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.18
                 HHHHHHHHHHGGG-S-SEEEEEEE-TTSSHHHHHHHHH CS
        MeaB  13 peakellerllakaGraqvvGltGvPGaGkstlvealg 50 
                 pe + ll+ ++ +  +++   + G  G Gkstl++a+ 
  EEA22217.1 644 PEKEPLLKSITMSVPESKISMIVGPVGCGKSTLLKAIL 681
                 678899999999999999999************99875 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0058
                  HHHHHHGGG-S-SEEEEEEE-TTSSHHHHHHHHHHHHHCTT--EEEEEE- CS
        MeaB   17 ellerllakaGraqvvGltGvPGaGkstlvealglelrrrGkrvavlavD 66  
                   +l+++  +    +++G+ G  G+Gks lv a+   +   G  +++  +D
  EEA22217.1 1250 PILKKIDLSIRSGEKIGICGRTGSGKSSLVLAIFRMVELSGGSITIDGID 1299
                  577777777777899***************99999888888888887777 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.0      0.14        65       6      22 ..     664     680 ..     659     704 .. 0.86
   2 ?    6.5   0.1     0.014       6.2       3      48 ..    1263    1311 ..    1261    1412 .. 0.63
   3 ?   -1.0   0.0       2.8   1.2e+03     123     170 ..    1386    1433 ..    1369    1459 .. 0.86

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.14
      AAA_24   6 liyGpsgiGKTtlakel 22 
                 +i+Gp g GK+tl+k +
  EEA22217.1 664 MIVGPVGCGKSTLLKAI 680
                 89***********9987 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.014
      AAA_24    3 lkiliyGpsgiGKTtlakelgpkplfidtekGlksldadkfpdie......s 48  
                   ki i G  g+GK++l++ +   + ++ + +G+  +d++++ +i+       
  EEA22217.1 1263 EKIGICGRTGSGKSSLVLAI---FRMVELSGGSITIDGIDLSTIPrqeiraR 1311
                  699****************9...99999999999999999999976644440 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 2.8
      AAA_24  123 knvifiahektrkdedpegeakytrlepklgkktanelkeevDlvlra 170 
                  +  i+i  e t ++++++ e +   ++ k ++ t  ++ +++D++l+ 
  EEA22217.1 1386 HSSILILDEATSNVDSKTDEIMQRVIREKFSNHTILAVAHKLDTILDF 1433
                  556888899999999999998999999999999999999999999985 PP

>> Viral_helicase1  Viral (Superfamily 1) RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   0.0    0.0038       1.7       5      41 ..     667     700 ..     663     724 .. 0.63
   2 ?    1.0   0.1      0.64   2.9e+02       5      21 ..    1269    1285 ..    1265    1301 .. 0.84

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.0038
  Viral_helicase1   5 GvpGcGKStlirkllrtsliltvnrptaelltegkpk 41 
                      G  GcGKStl++ +l +   + + + ++ ++t+++ +
       EEA22217.1 667 GPVGCGKSTLLKAILGE---IPPMHGSVYMATDQVAY 700
                      566************99...33444445555555533 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.64
  Viral_helicase1    5 GvpGcGKStlirkllrt 21  
                       G  G+GKS+l+  ++r+
       EEA22217.1 1269 GRTGSGKSSLVLAIFRM 1285
                       778***********999 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.0    0.0015      0.65       7      62 ..     650     703 ..     646     724 .. 0.76
   2 ?   -0.8   0.0       2.4   1.1e+03      20      42 ..    1265    1287 ..    1252    1420 .. 0.67

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0015
      AAA_11   7 reaiksalseseitliqGPPGtgKTktivellsqllsrrkseeeksakpriLvCap 62 
                 +++i+  + es+i++i GP G+gK++ + ++l ++ ++       +a+ ++ +C +
  EEA22217.1 650 LKSITMSVPESKISMIVGPVGCGKSTLLKAILGEIPPM--HGSVYMATDQVAYCDQ 703
                 578999999****************9999999988433..3445555555555555 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 2.4
      AAA_11   20 tliqGPPGtgKTktivellsqll 42  
                    i G  G+gK++ ++++++++ 
  EEA22217.1 1265 IGICGRTGSGKSSLVLAIFRMVE 1287
                  55777788888888888887763 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   0.0    0.0057       2.5       3      21 ..     663     681 ..     661     688 .. 0.88
   2 ?    1.6   0.1      0.53   2.4e+02       5      21 ..    1267    1283 ..    1264    1290 .. 0.84

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0057
                 EEEEC-TTTCHHHHHHHHH CS
       NACHT   3 vilqGeaGsGKTtLlqkla 21 
                 +++ G+ G+GK+tLl+ + 
  EEA22217.1 663 SMIVGPVGCGKSTLLKAIL 681
                 689*************996 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.53
                  EEC-TTTCHHHHHHHHH CS
       NACHT    5 lqGeaGsGKTtLlqkla 21  
                  + G+ GsGK+ L+  + 
  EEA22217.1 1267 ICGRTGSGKSSLVLAIF 1283
                  679*********98775 PP

>> PduV-EutP  Ethanolamine utilisation - propanediol utilisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.0    0.0029       1.3       2      24 ..     661     683 ..     660     705 .. 0.77
   2 ?   -0.2   0.1       1.7   7.8e+02       3      20 ..    1264    1281 ..    1262    1286 .. 0.85

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0029
   PduV-EutP   2 kkilliGkvgsGKttLtqalkge 24 
                 k  +++G+vg+GK tL +a+ ge
  EEA22217.1 661 KISMIVGPVGCGKSTLLKAILGE 683
                 5569**************99874 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 1.7
   PduV-EutP    3 killiGkvgsGKttLtqa 20  
                  ki + G++gsGK +L  a
  EEA22217.1 1264 KIGICGRTGSGKSSLVLA 1281
                  77789*********9865 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.1       1.3     6e+02      28      47 ..     665     684 ..     661     691 .. 0.88
   2 ?   10.1   0.4    0.0014      0.63      24      45 ..    1263    1284 ..    1253    1295 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 1.3
       DUF87  28 ilgsTGsGKSntvavLleel 47 
                 i+g  G GKS++ + +l e+
  EEA22217.1 665 IVGPVGCGKSTLLKAILGEI 684
                 77888***********9886 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.0014
       DUF87   24 rHlAilgsTGsGKSntvavLle 45  
                  + ++i g+TGsGKS +v  +++
  EEA22217.1 1263 EKIGICGRTGSGKSSLVLAIFR 1284
                  5789************988875 PP

>> ABC_ATPase  Predicted ATPase of the ABC class
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   0.1    0.0028       1.2     240     264 ..     655     680 ..     649     684 .. 0.89
   2 ?   -1.5   0.0       1.8   8.2e+02     307     349 ..     741     784 ..     734     803 .. 0.87
   3 ?   -1.7   0.2       2.1   9.5e+02     335     370 ..    1381    1415 ..    1375    1438 .. 0.74

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0028
                 EEE-SS.EEEEEE-TTSSHHHHHHHH CS
  ABC_ATPase 240 mgipkG.vtlIvGggfhGKsTLLeAl 264
                 m +p+  + +IvG+   GKsTLL+A+
  EEA22217.1 655 MSVPESkISMIVGPVGCGKSTLLKAI 680
                 7888877******************9 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1.8
                 ---CCC--STTEEESS-.-HHHHHHHHHHHHHHTT-SEEEEEGG CS
  ABC_ATPase 307 nnLPegkdttkfstedA.SGStsqAanimealeagakllLiDED 349
                 ++LP+g++t   s   A SG   q  ++++a+ a+ kl+++D  
  EEA22217.1 741 RQLPQGDQTMIGSKGVAlSGGQCQRIALARAVYAKRKLVILDDP 784
                 79********88888777************************84 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 2.1
                  HHHHTT-SEEEEEGGGS-HHHH---HHHHHHS-GGG CS
  ABC_ATPase  335 ealeagakllLiDEDtsAtNlmirDermqelvskek 370 
                  +a+ + +++l++DE ts +     De mq+++ ++ 
  EEA22217.1 1381 RAMLRHSSILILDEATSNVDSKT-DEIMQRVIREKF 1415
                  667788999*******9999877.******996543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1520 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       825  (0.0460148); expected 358.6 (0.02)
Passed bias filter:                      506  (0.0282224); expected 358.6 (0.02)
Passed Vit filter:                        84  (0.00468515); expected 17.9 (0.001)
Passed Fwd filter:                        40  (0.00223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              40  [number of targets reported over threshold]
# CPU time: 1.04u 0.26s 00:00:01.30 Elapsed: 00:00:00.44
# Mc/sec: 10303.68
//
Query:       EEA22218.1  [L=7901]
Description: nonribosomal peptide synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
          0 1363.5   1.0    9.8e-56  189.3   0.0   12.7 11  Condensation   Condensation domain
          0 1263.6   0.0    1.4e-77  261.1   0.0    5.2  5  AMP-binding    AMP-binding enzyme
    1.2e-85  281.8   9.2    1.4e-12   47.8   0.0    7.9  7  PP-binding     Phosphopantetheine attachment site
    1.4e-09   38.8   0.0       0.76   10.8   0.0    5.7  5  AMP-binding_C  AMP-binding enzyme C-terminal domain
     0.0004   19.1   0.2        1.1    7.8   0.0    3.1  3  Transferase    Transferase family
  ------ inclusion threshold ------
      0.042   13.9   0.6        7.9    6.5   0.1    4.3  4  DUF600         Protein of unknown function, DUF600
        4.9    7.5   5.2         35    4.8   0.1    4.0  4  DUF5122        Domain of unknown function (DUF5122) beta-prop


Domain annotation for each model (and alignments):
>> Condensation  Condensation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.2   0.0   8.3e-05      0.21     226     275 ..      31      80 ..       4      95 .. 0.76
   2 ?    1.4   0.1     0.039     1e+02     355     456 ..     143     237 ..     118     238 .. 0.74
   3 !  106.4   0.1   5.5e-34   1.4e-30       7     439 ..     885    1313 ..     882    1323 .. 0.77
   4 !  179.6   0.0   3.4e-56   8.7e-53       1     456 [.    1353    1781 ..    1353    1782 .. 0.86
   5 !  141.1   0.0   1.7e-44   4.3e-41       2     449 ..    2458    2860 ..    2457    2866 .. 0.82
   6 !  135.3   0.0   9.4e-43   2.4e-39       4     436 ..    3504    3934 ..    3501    3947 .. 0.81
   7 !  189.3   0.0   3.8e-59   9.8e-56       2     436 ..    3977    4386 ..    3976    4402 .. 0.88
   8 !  161.8   1.1   8.6e-51   2.2e-47       2     456 ..    5085    5505 ..    5084    5506 .. 0.84
   9 !  118.7   0.0     1e-37   2.6e-34       7     435 ..    6147    6571 ..    6143    6583 .. 0.77
  10 !  185.7   0.0   4.7e-58   1.2e-54       2     447 ..    6616    7038 ..    6615    7047 .. 0.86
  11 !  111.9   0.0   1.1e-35   2.9e-32      30     447 ..    7314    7705 ..    7288    7709 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 8.3e-05
                   -EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEE CS
  Condensation 226 drlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvg 275
                   +r + +  +  ++k++++ k+ ++  +++l+aa++++L+ ytg +++ +g
    EEA22218.1  31 KRRMCSRINCDAQKVKNIFKDDEIGAKNLLQAAWAMVLYHYTGMEEVCFG 80 
                   34444444567899********************************9998 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.039
                   EEEESSS-HHCCCEEECCCCSEEECEE...E.....SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTTSBCCC-----HH CS
  Condensation 355 vfsfenylgqeseeeesqlselklsvssveaeeeskydlsleasetngkltikieYntslFdeetierflerlkelleqviehpeqklselkllsda 451
                   +f++ n     s+ ++++ ++l  ++    ++  +k  + + a+ tng++++ +eY+    + ++ + ++e++ ++l+ ++e+   ++++l+ ++d 
    EEA22218.1 143 MFQIRN-----SSDNAFSPTALASQQA--AMSLPEKCKFRILAKYTNGAFSVFLEYKHPDVSANFASIVSETFSRMLHGLLEESPCTVQDLSKITDS 232
                   333333.....5555555555554422..234455666788899999*************************************9999999999999 PP

                   HHHHH CS
  Condensation 452 ekekL 456
                   +++++
    EEA22218.1 233 DMRQI 237
                   99887 PP

  == domain 3  score: 106.4 bits;  conditional E-value: 5.5e-34
                    XXCCHHHHHHHHHHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-.TT-----EEEE-T..TSSSHHHHHH CS
  Condensation    7 lspaQkrmwflekleeessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvil.eerevelevleisdleeseeeeaie 100 
                    lsp+Q   + +e  +++s ++n+++ l++++++ ++ le+a++ +++rh  LR +f  +e ++++Q  l ++ +v+   +++   + s+  ++++
    EEA22218.1  885 LSPIQ--KLHFEARDDNSGHFNQSFFLRVNQAITPQNLEDAIKVIVSRHSMLRARFFYDESKKQWQQRLtDHNQVSH-RFNVH--TSSS-RAQVK 973 
                    99***..9**************************************************9999888877736666665.66666..4444.56799 PP

                    HHHHHHHTC--SCCCS-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHHHHHHH CS
  Condensation  101 efaqkdlqepfdLekgpLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskdlekee 195 
                    +++  d+q +++  +gp + + lf++++++ ll l  HH+ivD vS++++l+dl +l   l  +++  lp++ pY+++   + + + s   e++ 
    EEA22218.1  974 NAIA-DSQAGLNAVSGPVVAIDLFQMNDRSQLLSLIGHHLIVDLVSWRVILEDLEELL--LHPQSSSLLPPTLPYQSWSRLQWD-QISGLGEQNP 1064
                    9999.5***************************************************9..66777777778888****977544.4444444444 PP

                    HHHHHHHH......S---BSS---SS---S-EEEEEE.EE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHH.HT-SEEEEEEEEESSTT..CST CS
  Condensation  196 aYWseqlegelpvlqLpkdkarpakrsfkadrlsikl.deeteeklrklakeqgvtlndvllaalgllLsky.tgqddivvgteisgRes..eik 286 
                    +  +++  g l +  + +   ++  ++++     +++ +e+t  +l+++ +   ++  d+l aal     k+ t ++  v+  e++gRe     +
    EEA22218.1 1065 STAQNVPLGDLSYWGITDA--ENTYGQVSC--EGFEIdAETTSILLNEANSPVRTEAVDILVAALLHSFGKIfTDHELPVIYNEGHGREPwdNSI 1155
                    3334444444444444444..333333443..34555336667788999999************99999997466777799********998889 PP

                    CHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEE.EEESSS-HH..........CCCEEE CS
  Condensation  287 diermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpv.fsfenylgq..........eseeee 370 
                    d++r+vG+F+ + P+ ++  +  +  + + +vk++ ++++++ +  + +    l  ++     + f+p+ ++f nylg                 
    EEA22218.1 1156 DVSRTVGWFTIIHPIFVQATALRDWIDTLVQVKDCRRRVKDNGREYFARS--ILGGENI----KAFKPMeITF-NYLGRyqqlektgalF----- 1238
                    ***************************************77765544443..2332332....2366543888.**99987654444441..... PP

                    CCCC........SEEECEE....E.....SSE.EEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTT CS
  Condensation  371 sqls........elklsvssve.aeeeskydl.sleasetngkltikieYntslFdeetierflerlkelleqviehpe 439 
                       s        + + +   +  a+++  + l +++a+++++ l++++++n +  ++e i+++ +  +++l+q++++  
    EEA22218.1 1239 ---SpveglageTSQGG-GAADfAKTTPRFGLfEISAVIVQDILRFTFSFNGNMRHQERIRQWVTDCQNTLSQMTKDLV 1313
                    ...23333333222222.23444466677765489999999********************************999865 PP

  == domain 4  score: 179.6 bits;  conditional E-value: 3.4e-56
                    EEEEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES-....--HHHHHHHHHHHHHH-SSCCEEEEE....TTEEEEEE-TT-----EEEE-T. CS
  Condensation    1 vqdeyplspaQkrmwflekleeessaynmqavlklege....ldlerlekalqelierhdaLRtvflee..engepvQvileerevelevleisd 89  
                    v+d+yp sp+Q++++       + s y    + +++ +    +d ++l++a+q+l++rh  LRtvf+e+   ++   Q++l +  +++++l  +d
    EEA22218.1 1353 VEDIYPCSPMQRGLLLSTTR--DISFYAARGTYEVKANngnsIDAKLLSRAWQQLVDRHAMLRTVFVENltSEDLYSQIVLRKYACSINILRCTD 1445
                    5899*******777655444..577777777777764333349************************9643566678***********9999994 PP

                    .TSSSHHHHHHHHHHHHHTC--SCCCS.-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHH CS
  Condensation   90 leeseeeeaieefaqkdlqepfdLekg.pLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweq 183 
                      e++    +++++     +p++ ++  pL ++ +   ++ ++++ l++ H+i+DGvS++i+lrdl k+Y       +l++++k+ +++++    
    EEA22218.1 1446 --EDN----VQTVLD---IHPMQPNRRkPLHQFTICVTETGKVFCRLELSHVIMDGVSISIMLRDLEKAY-----SGNLQTSPKPLFSNFVSY-- 1524
                    ..333....555666...4677766666******************************************.....445577777778888877.. PP

                    HHHCSHHHHHHHHHHHHHHH......S.---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEE CS
  Condensation  184 qyleskdlekeeaYWseqlegelpvlq.LpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgte 277 
                      l+ +    + +YW+ +l+g +p +  +++d   + +r+++    +++ld +   +l+++++++g t+ + l+aa++l+L  ytg +d+ +g  
    EEA22218.1 1525 --LQAQPKAASMNYWKSYLSGVEPCHMpVLND--GSSSRQYN----TLRLDFQRLGLLQSTCEKHGLTIANALHAAWALTLRCYTGCNDVCFGYL 1611
                    ..6667777999*********88855555555..66666666....8889999****************************************** PP

                    EESSTTCSTCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEECC CS
  Condensation  278 isgReseikdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeeesq 372 
                     s R  + + ie++vG  +n+l+ r++++ +  +  l++ ++ed +++ p + + l ++++ l+l  +     Lf++ +s+        ++e  q
    EEA22218.1 1612 LSERDLPLDMIEDTVGPMINMLACRVNMSSESVLMRLVEGIQEDYMESAPFKHISLADVQHGLNLSGT----ALFNTCLSYRK----LPSAESGQ 1698
                    ****************************************************************9997....6********66....44455555 PP

                    CCSEEECEE....E.....SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTTSBCCC-----HHHHHHH CS
  Condensation  373 lselklsvssve.aeeeskydlsleasetngkltikieYntslFdeetierflerlkelleqviehpeqklselkllsdaekekL 456 
                    + ++ +s    +  ++ ++y +++++  ++ +  i++++ t+  ++++ ++++++++++le++ie+pe++l +l+ ++  + +++
    EEA22218.1 1699 QPAIRFS--ECGgLHDPTEYLVTINVEASDTDAVIDLDFWTDMLSQAQARNIADTFIRALENMIEQPEAQLGQLNHVPASNWQQI 1781
                    5555555..566699************************************************************9998877765 PP

  == domain 5  score: 141.1 bits;  conditional E-value: 1.7e-44
                    EEEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T..TSSSHH CS
  Condensation    2 qdeyplspaQkrmwflekleeessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvileerevelevleisdleeseee 96  
                    +d++p s +Q+++  l+    ++ +y++q +  l  ++++er++ a+q l +   +LRt++l+ +n+ ++Qv+l e++           + +   
    EEA22218.1 2458 EDILPCSAIQEGLIALSST--QQGSYVTQNIYDLPDSINIERFKAAWQRLYQNESILRTRILHSKNNGFLQVVLREEPEWT--------SSQP-- 2540
                    7899********9877765..5889*************************************************8877444........2233.. PP

                    HHHHHHHHHHHTC--SCCCS.-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--.HHHHHHHHHHHHCSH CS
  Condensation   97 eaieefaqkdlqepfdLekg.pLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktp.Ykdyaeweqqylesk 189 
                         + +     +   ++g  L +  +++ ++ +l ++++ HH i DG+S++ l+++l++ Y    + ++l     +  Y+ ++e  +      
    EEA22218.1 2541 -----LSR-----SVPGSNGgRLSQYTIIQDTSGKLRFIWTAHHAIYDGWSIPKLFNKLQRYY----EHSSLAIEHNPCsYSHFIEYAS----RI 2617
                    .....222.....444455559*****************************************....5555555544446999999844....45 PP

                    HHHHHHHHHHHHHH......S---BSS---SS---.S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEESSTT CS
  Condensation  190 dlekeeaYWseqlegelpvlqLpkdkarpakrsfk.adrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisgRes 283 
                    d  + +a+W +ql+g+ + +q+p+  + + k++ k  ++l+++l           ++ ++vtl ++  aa++l++s+y+ ++div+g ++ gR  
    EEA22218.1 2618 DADERKAFWVQQLDGFSA-VQFPALPNASYKSNPKiRETLKFNL---------PEQRPTEVTLPSLIRAAWALTISTYSYSEDIVFGEIMTGRDI 2702
                    56679**********776.7777773333333333024555555.........557899************************************ PP

                    CSTCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEECCCCSEEE CS
  Condensation  284 eikdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeeesqlselkl 378 
                    ++ +i++m+G  +++lP+r++++ + t + +++++++++ ++ p+q+ +l++++  +   ++      f++ fs+    g+    +   +  +k+
    EEA22218.1 2703 PVPGIDDMIGPALSILPMRLQLDLSLTIARFLQQTQAQATSIIPYQSAGLQNIQGFSHDAKS---ACEFQTLFSIAH--GE----SDDVEGVMKF 2788
                    999*****************************************************997776...4569******33..22....2222233333 PP

                    CEE...E.....SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHST.TSBCCC----- CS
  Condensation  379 svssveaeeeskydlsleasetngkltikieYntslFdeetierflerlkelleqviehp.eqklselklls 449 
                        +++ +   y l+++ ++ +++l+++i++ + +    +++r++ +++ +l+++ +   e++ls l+++s
    EEA22218.1 2789 LSANSGDTNFFTYPLNVSCFIWESDLEVQIQFDNHVIPLPQLKRVMGQFEATLHKLCSAGqEERLSGLQMIS 2860
                    322223566777******************************************998765144556666655 PP

  == domain 6  score: 135.3 bits;  conditional E-value: 9.4e-43
                    EEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-..TT-----EEEE-T..TSSSHH CS
  Condensation    4 eyplspaQkrmwflekleeessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvil..eerevelevleisdleeseee 96  
                    e  lsp+Q   +++  +++++s++n+++++ l++++  + +++a+ +l++ h  LR +f ++ ng   Q+il   ++++ ++++e  d   +e  
    EEA22218.1 3504 EFDLSPIQ--SLYFRCMSGQTSHFNQSIMIDLTSSVSNDQVQSAMSKLVSVHSMLRARFSRDGNGIWKQRILqdAQSSYGFRIVEYFD--PDE-- 3592
                    6789****..**************************************************************6666677777777773..333.. PP

                    HHHHHHHHHHHTC--SCCCS-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHHH CS
  Condensation   97 eaieefaqkdlqepfdLekgpLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskdl 191 
                      + e +++ +q+++d+  gp + a  f+ ++ +  l++  HH++vD +S+gi+++dl +l     +g+++   q+ +++++   + +y ++k+ 
    EEA22218.1 3593 --LAEEVEE-TQKSLDIIHGPVMAATFFEDDTAKSKLFICAHHLVVDVISWGIIVQDLEDLL----QGRQVAGDQSVSFQRWCRLQLDYVKEKKN 3680
                    ..3344443.788**********************************************999....*******************9998888755 PP

                    HHHHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHH.HHSTSS-HHHHHHHHHHHHHHHHHT-SEEE..EEEEEESSTT CS
  Condensation  192 ekeeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrkl.akeqgvtlndvllaalgllLskytgqddiv..vgteisgRes 283 
                     +     +++ + e++   + kd  ++  +++     +i+ld++t+++l  +     + ++ dvlla+l l  +++ ++++ +  +  e++gRe 
    EEA22218.1 3681 TDLLP-LDDIRAAEMDFWGM-KD-MPNTHGNVV--VEEIELDSTTTDALLAIiNGPLNCDIVDVLLAVLLLSFHRVFSSRKSMpcIFNEGHGREP 3770
                    55544.34555543443333.33.344445555..4677887777776665505689*******************8888776447889*****9 PP

                    ..CSTCHHC--SS-EEEEEEEE....E--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HH....CCCE CS
  Condensation  284 ..eikdiermvGlFvntlPlri....dvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgq....esee 368 
                      + +d++r+vG+F+ + P+ +    +++++++  + i  vk+  +++ p +g+p+   ++ l  + +e+       +++f nylgq    +++e
    EEA22218.1 3771 wdPSIDLSRTVGWFTTMSPVHLptdfNIENGNDIHKCIGWVKALRRRT-PGKGMPYFA-QRLLTWEGSEKYRHHWPMEMTF-NYLGQhkevKESE 3862
                    9999*************888762222678888999******9999999.******976.56777788888888999*****.*****76442222 PP

                    EECCCC..SEEECEE....E.....SSE.EEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHH CS
  Condensation  369 eesqls..elklsvssve.aeeeskydl.sleasetngkltikieYntslFdeetierflerlkelleqvie 436 
                       ql+  +++  +s +    ++  + l +++a ++ng+++++i Yn+s  ++e+i++++e+ k+++ qv  
    EEA22218.1 3863 ILLQLTngTGQTVNSASDiGPDVPRFSLiEISAAIVNGSMSMSILYNKSMKKQESIRQWIEYCKDMICQVPM 3934
                    2223324444444566667789999*9869************************************999855 PP

  == domain 7  score: 189.3 bits;  conditional E-value: 3.8e-59
                    EEEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEE...EES---HHHHHHHHHHHHHH-SSCCEEEEE....TTEEEEEE-TT-----EEEE-T..T CS
  Condensation    2 qdeyplspaQkrmwflekleeessaynmqavlk...legeldlerlekalqelierhdaLRtvfle..eengepvQvileerevelevleisdle 91  
                     d+yp s++Q +++  + ++++++ay   + +    l+g+ld++rl +a+q++++rh +LRt+f+   +e   + Qv+ ++  +++ vle++  e
    EEA22218.1 3977 HDIYPCSSMQHGILLSQLMDPKTYAYRAIFEVDlpsLHGKLDVQRLATAWQSVVDRHTSLRTTFIDgnHEASLMDQVVFKSCRANIDVLEAA--E 4069
                    589***********************988887522279**************************97433455567999999999*9999999..5 PP

                    SSSHHHHHHHHHHHHHTC--SCCCS.-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHH CS
  Condensation   92 eseeeeaieefaqkdlqepfdLekg.pLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqy 185 
                    e++  +++ + +      +++ ++g  L r a+ + ++ ++++ +++   i+DG S++i++rdl+++Y     g  + + + ++Y+d++ +    
    EEA22218.1 4070 EDA--RKMLAGLP-----DMNFKNGnQLHRLAICTNKTGKFFCRFDISNGIADGTSMPIIFRDLSRAY----MGLAPVTERQPQYSDFVAH---- 4149
                    554..55666666.....79****99******************************************....888888888888*******.... PP

                    HCSHHHHHHHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEES CS
  Condensation  186 leskdlekeeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisg 280 
                    l sk  ek  aYW+++leg++p   +p+  ++ ++++ +  +  i l  +   ++++l+k+ g+t+ ++++++++++L +ytg+d++ +g + sg
    EEA22218.1 4150 LLSKPKEKGVAYWKKYLEGSEP-CLFPSL-INDQQKEKSLGSEIIIL--KNNPAIKELCKNMGITMSSLFQFVWAMVLRTYTGSDEVCFGYISSG 4240
                    99999**************888.446777.55566666666777788..67889***************************************** PP

                    STTCSTCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEECCCCS CS
  Condensation  281 ReseikdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeeesqlse 375 
                    R  ++++ie++vG F+n+l   i++ ++  + +++k++++d  k+++hq + l e+++ l l  +    pLf++ f+f+        +  +  s+
    EEA22218.1 4241 RDVPMQNIEEAVGAFINMLIYKIHLTDDLPLMKALKKTQRDFIKSMEHQAVSLAEVQHALGLADT----PLFNTAFTFQR------RSGLEVDST 4325
                    *************************************************************9996....*********88......333444444 PP

                    EEECEE...E.....SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHH CS
  Condensation  376 lklsvssveaeeeskydlsleasetngkltikieYntslFdeetierflerlkelleqvie 436 
                      ls +s+  ++ s+y +++++   ++  +i++++ ++  +++++++++++++++++++++
    EEA22218.1 4326 PMLSFKSFDSHDPSEYKIAVNIEMMDSITEIHFSFWEDYLSSAQVKNVADTFEQIINEITT 4386
                    444455555789999*********99*******************************9976 PP

  == domain 8  score: 161.8 bits;  conditional E-value: 8.6e-51
                    EEEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T..TSSSHH CS
  Condensation    2 qdeyplspaQkrmwflekleeessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvileerevelevleisdleeseee 96  
                    +d+yp s +Q+++ + +   +++ ay+   +lkl + +d++ +++++q+l++  d+LRt++ + +  e++Qv+l+++++++   + s   +s   
    EEA22218.1 5085 ADIYPCSALQEGLIT-SS-VQQQGAYISRNILKLGPHVDINQFKDSWQQLVDEFDILRTRIPHTASSEFLQVVLKQQQISW---HHS---DS--- 5168
                    689*******99644.44.45899*********************************************************...333...22... PP

                    HHHHHHHHHHHTC--SCCCS-SEEEEEEESSTT.EEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHH CS
  Condensation   97 eaieefaqkdlqepfdLekgpLfraalfkiaen.rlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskd 190 
                      +e+++  d++  f+ e+g L r  l+k +++   ++++ +HH + D++ l illr  +++Y   +kg+++ +   ++Y++++      le+++
    EEA22218.1 5169 --VESALD-DSSTVFNSESGMLARYILVKESSSsATYFVWLIHHALYDAWGLAILLRRVQEIY--FKKGQSTTK---PSYASFISY----LEKRN 5251
                    ..334444.46679**************97655157899************************..999999776...557777766....78899 PP

                    HHHHHHHHHHHHH......S---BSS---SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEESSTTCS CS
  Condensation  191 lekeeaYWseqlegelpvlqLpkdkarpakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgteisgResei 285 
                    l+++ ++W+ +l+++ p   +p+  a++ + + + d++s +l  + + ++ +   + g+tl  +  aa++l+Ls  t+++d+ +g + sgR+  i
    EEA22218.1 5252 LQDSGDFWKAYLAKSSP-SHFPPL-ASQLELDGQ-DTTSKTL--TQKTTIPQQFLNLGITLPILIRAAWALVLSSRTQSSDVCFGETLSGRNTDI 5341
                    *************9776.669999.555555555.7888888..5556788888899************************************99 PP

                    TCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEECCCCSEEECE CS
  Condensation  286 kdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeeesqlselklsv 380 
                     di +  G  + t+P  ++v+ + +  +++ +++++  ++ phq ++l+ + k+l +q+++     f   ++ +     ++++  + ++ ++++ 
    EEA22218.1 5342 PDITDLAGPVLTTVPTYVNVNTKSKIKDYLLEIQKMSTEMIPHQHFGLQHI-KKLGNQHAAIC--QFRNLIVVQTAEAADNDNLWEVQDNGDIG- 5432
                    9**************************************************.66666886322..25555555443333444333444445555. PP

                    E...E.....SSEEEEEEETTSSEEEEEEEETTT...S-HHHHHHHHHHHHHHHHHHHHSTTSBCCC-----HHHHHHH CS
  Condensation  381 ssveaeeeskydlsleasetngkltikieYntsl...FdeetierflerlkelleqviehpeqklselkllsdaekekL 456 
                          +   y l +e ++ +++ +i+++Y +++   ++ e i+  l+++++ l  v +  ++ l ++++ls+++k+++
    EEA22218.1 5433 ------SFFTYPLVVECKILGSSVEINFHYDENVitrWELERISFQLSHVLRQLGSVNTSSTNLLTSIDMLSPEDKKEI 5505
                    ......5566*********************975333888889999999999999999999999**********99987 PP

  == domain 9  score: 118.7 bits;  conditional E-value: 1e-37
                    XXCCHHHHHHHHHHSSSSSTTEEEEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T..TSSSHHHHHHH CS
  Condensation    7 lspaQkrmwflekleeessaynmqavlklegeldlerlekalqelierhdaLRtvfleeengepvQvileerevelevleisdleeseeeeaiee 101 
                    lsp+Q+  + ++k +++ss +n++ +l+l+  l  +r+++al+++++    LR +f+ +++ge  Q i+++ e+++++ + +  + se      +
    EEA22218.1 6147 LSPIQQMYFLTAKGHQGSSRFNQSYTLRLSRHLSADRVQSALRAIVSSQSMLRARFKLNATGEWEQQISSDTEFSFRFRYHRIGSLSE----GVK 6237
                    8****766677999*******************************************************8888888666666223333....345 PP

                    HHHHHHTC--SCCCS-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHHHHHHHH CS
  Condensation  102 faqkdlqepfdLekgpLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskdlekeea 196 
                    ++  d+q++ ++++gp + a +f+++en+ +l+l  HH++vD vS++i+l+dl ++    e+g+ + +++ + ++++ +      +s++++++ +
    EEA22218.1 6238 IVG-DSQRDVNIYDGPILVADMFSRSENEQYLFLGAHHLVVDVVSWRIILQDLEDIL---ESGSLPTDKPLS-FQSWCKL-----QSDHVKRSTD 6322
                    666.4889************************************************9...899999998888.9999987.....8889999887 PP

                    HHHHHHH......S---B....SS---SS--.-S-EEEEEEEE-.S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEE.EEEEEEESSTT. CS
  Condensation  197 YWseqlegelpvlqLpkd....karpakrsf.kadrlsikldee.teeklrklakeqgvtlndvllaalgllLskytgqddi.vvgteisgRes. 283 
                      +  ++       Lp++      ++ ++++ + +r +++lde  t++++++ ++  g++  d++l+a+      + + + +  v  e++gRe  
    EEA22218.1 6323 VYKLPFN------VLPANlgywGMENVSNTYgDVERRTFTLDEGmTTSTMTSCHEIFGTEPVDIFLTAVIHSFRLVFKDRFLpTVFNEGHGRETw 6411
                    6665555......4776666664455555552447999999776157889999999************99888666555544245569******9 PP

                    .CSTCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHH.HHHCSS.SS-SSSS-S-SEEEEESSS-HH..........CC CS
  Condensation  284 .eikdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgyplee.LvkdlelqrkesrspLfdpvfsfenylgq..........es 366 
                     +++d++r+vG+F+n+ Pl +++ e+++  + +krvk++ ++++++ +  l +        +r    +  +  ++ f nylg+           +
    EEA22218.1 6412 dSKIDLSRTVGWFTNISPLQVTL-ESDDVLDTLKRVKDTRRSSKEAGKAYLAQrFFAAR--DRPLPSQSDVPMEILF-NYLGSmqqlerddsvLQ 6502
                    988********************.77779999******999997776655443133222..2222223335566666.66666655555566544 PP

                    CEEECCCCSEEECEE...E.....SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHH CS
  Condensation  367 eeeesqlselklsvssveaeeeskydlsleasetngkltikieYntslFdeetierflerlkelleqvi 435 
                     +++  +++ +l+v  ++  +++   ++++a  ++ +l++ + +n    + ++++r+++  k +le+++
    EEA22218.1 6503 NTDMGLEEADPLEVGDMGCDTTRLALFEISAAVVQHRLEFAFMFNGRMKRLSEVNRWMSECKWILEEIV 6571
                    4444444555555556663333333345666666699**********99************99999986 PP

  == domain 10  score: 185.7 bits;  conditional E-value: 4.7e-58
                    EEEEEXXCCHHHHHHHHHHSSSSSTTEEEEEEEEES-.....--HHHHHHHHHHHHHH-SSCCEEEEE....TTEEEEEE-TT-----EEEE-T. CS
  Condensation    2 qdeyplspaQkrmwflekleeessaynmqavlklege.....ldlerlekalqelierhdaLRtvflee..engepvQvileerevelevleisd 89  
                    +++yp sp Q++m+  +    +++ay+  +v++++g+     +d+  l +a+q++++rh aLRtvf++   +   + Q +l + + ++  +e  d
    EEA22218.1 6616 EEVYPCSPTQEGMLLSQLR--DPKAYVFHIVFEVTGAnprqtVDPLKLITAWQKVVDRHAALRTVFVNStyKGSSFDQAVLHNVDSDVIHVECDD 6708
                    789**********976554..5999********9986333337888999*****************99545788999*****9999997777776 PP

                    .TSSSHHHHHHHHHHHHHTC--SCCCS-SEEEEEEESSTTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHH CS
  Condensation   90 leeseeeeaieefaqkdlqepfdLekgpLfraalfkiaenrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqq 184 
                        ++ + i+ + +     + + +++++ +  +    + r+++ ++v H ++DG S++il+ dl+ +Y        lp+++ + Y+dy+     
    EEA22218.1 6709 SVVLAQLQSISLYER-----NARRKQKIPHQLTVCVTPSGRVFMKIEVNHAVIDGGSTPILIHDLQLAY-----DGLLPDGRGPLYSDYIRF--- 6790
                    666666666666666.....78888899999999999********************************.....55567777777*****98... PP

                    HHCSHHHHHHHHHHHHHHH......S---BSS-.--SS---S-EEEEEEEE-S-HHHHHHHHSTSS-HHHHHHHHHHHHHHHHHT-SEEEEEEEE CS
  Condensation  185 yleskdlekeeaYWseqlegelpvlqLpkdkar.pakrsfkadrlsikldeeteeklrklakeqgvtlndvllaalgllLskytgqddivvgtei 278 
                      +s   +++  YW+ +l+g  +   +p+ k + + +r++   +l++  + +  + +++ ++ +gvtl +v +aa++l+L kytg+dd+ +g   
    EEA22218.1 6791 -VKSHSPKDDIVYWKRYLSG-VQACYFPRLKSTfSSQRRLA--SLQF--NFSHWQDVQRYCERTGVTLANVIQAAWALVLRKYTGSDDVCFGYLS 6879
                    .66677788999********.66677999822202233333..4444..5567799*************************************** PP

                    ESSTTCSTCHHC--SS-EEEEEEEEE--TT-BHHHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEECCC CS
  Condensation  279 sgReseikdiermvGlFvntlPlridvkeaktfselikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeeesql 373 
                    +gR  ++ +i++++G+F+n+l  r++++ ++ ++e+ + +++d ++a phq+  l +++++l lq k    ++f++ +s++n     s +e  ++
    EEA22218.1 6880 AGRDAPVTRIQETIGVFINMLCCRVRLSSSQLLAEIPSVIQDDYVRAIPHQRCSLAQVQHELGLQGK----QIFNTALSIQN----HSASEVVDE 6966
                    ******************************************************************9....5**********....555555555 PP

                    CSEEECEE...E.....SSEEEEEEETTSSEEEEEEEETTTS-HHHHHHHHHHHHHHHHHHHHSTTSBCCC--- CS
  Condensation  374 selklsvssveaeeeskydlsleasetngkltikieYntslFdeetierflerlkelleqviehpeqklselkl 447 
                     +l ++  ++ea++ s+y l+l++ +  g+  i + Y t+ F++e  + ++++l ++l++++++p++++s+l+ 
    EEA22218.1 6967 GSLVFT--TQEAHDPSEYSLTLNIETGRGQEGIVFRYWTDMFSSEHASDISKTLSNILHAFAQDPTETISRLSK 7038
                    555555..66799********************************************************99765 PP

  == domain 11  score: 111.9 bits;  conditional E-value: 1.1e-35
                    EEEEEEES---HHHHHHHHHHHHHH-SSCCEEEEE..TTEEEEEE-TT-----EEEE-T..TSSSHHHHHHHHHHHHHTC--SCCCS-SEEEEEE CS
  Condensation   30 qavlklegeldlerlekalqelierhdaLRtvfleeengepvQvileerevelevleisdleeseeeeaieefaqkdlqepfdLekgpLfraalf 124 
                     ++l  +g ld  rl+++   +++  d+LRtvf+   +g+++Qvil +   e+ v e      ++ +e ++ ++q+d+ e+ + + +p +++ ++
    EEA22218.1 7314 FFCLDGHGPLDFRRLKQSCFRVVHAFDILRTVFVAS-KGRFLQVILRKVRPEFSVYETD----ESLDEFTSVLQQRDITEGVK-QGEPFVQFVIV 7402
                    4689999**************************876.*********9999999777666....33456678888888888764.55699999999 PP

                    ESS.TTEEEEEEEEECCT--TTTHHHHHHHHHHHHHHHHTT-------S--HHHHHHHHHHHHCSHHHHHHHHHHHHHHH......S---BSS-- CS
  Condensation  125 kia.enrlllllsvHHiivDGvSlgillrdlaklYqqlekgeelplpqktpYkdyaeweqqyleskdlekeeaYWseqlegelpvlqLpkdkarp 218 
                    + + ++r+ ++l++ H   DGvSl+ +l  + + Y    +g ++p+p  + +++++ + +++ + +    + ++W+++l+g   ++++ +++++p
    EEA22218.1 7403 REKnTDRHRIILRLSHAQYDGVSLPRILSAIKAGY----EGGPIPSP-AS-FANFVRESARIVTAD----HYQHWRTLLSG-SRMTEMVNRHESP 7486
                    85416799***************************....****9994.44.9******77777666....6679******9.6666677764444 PP

                    -SS---S-EEEEEEEE-S-HHHHHHHHST.SS-HHHHHHHHHHHHHHHHHT-SEEEEEEEEESSTT.CSTCHHC--SS-EEEEEEEEE--TT-BH CS
  Condensation  219 akrsfkadrlsikldeeteeklrklakeq.gvtlndvllaalgllLskytgqddivvgteisgRes.eikdiermvGlFvntlPlridvkeaktf 311 
                      ++++        +e + +++r    ++ + t  +v  aa++l+L ++tg+ div+g +isgR+  +i ++e+mvG   n++P+r+   e+ t 
    EEA22218.1 7487 GYKRLR-----A-SNEGLRKTIRVPSMAHgNLTTATVIKAAWALTLARITGSADIVFGHTISGRNTaAITGVESMVGPCMNIVPVRVVFGEKWTV 7575
                    444444.....3.3577788888765555158999******************************99999************************* PP

                    HHHHHHHHHHHHHHHCCTTS-HHHHHHCSS.SS-SSSS-S-SEEEEESSS-HHCCCEEECCCCSEEECEE....E.....SSEEEEEEETTSSEE CS
  Condensation  312 selikrvkedllkaephqgypleeLvkdlelqrkesrspLfdpvfsfenylgqeseeeesqlselklsvssve.aeeeskydlsleasetngklt 405 
                     +l++ ++++++  +p++  ++ ++++++  +   s +  f++v++        ++++e ql e  ++v+ v+ +ee s++ ++ +  +  ++ +
    EEA22218.1 7576 LDLLRYIQDQQVANMPYEALGFRQIIHKCTDWPR-STH--FSTVLQHDA----ANSSNEIQLGENIYTVKAVGsDEEMSDFSVNSKSLD-RDRVE 7662
                    *****************************98885.444..555555544....778899999999999999**9999999999988888.88888 PP

                    EEEEEETTTS-H.HHHHHHHHHHHHHHHHHHHSTTSBCCC--- CS
  Condensation  406 ikieYntslFde.etierflerlkelleqviehpeqklselkl 447 
                    i ++++ ++    +  +r+l++l ++ e ++++p++ l + + 
    EEA22218.1 7663 IVLSFSVDEHVTmSLAQRVLDMLCDTAESFTANPDMALPSPSS 7705
                    8888888765441445777777778888888888877766555 PP

>> AMP-binding  AMP-binding enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  261.1   0.0   5.5e-81   1.4e-77       2     422 ..     257     657 ..     256     658 .. 0.89
   2 !  254.3   0.0   6.5e-79   1.7e-75       1     422 [.    1800    2204 ..    1800    2205 .. 0.87
   3 !  239.8   0.0   1.6e-74   4.1e-71       3     422 ..    2889    3283 ..    2887    3284 .. 0.85
   4 !  241.5   0.0   4.8e-75   1.2e-71       2     422 ..    4428    4832 ..    4427    4833 .. 0.85
   5 !  260.4   0.0     9e-81   2.3e-77       2     422 ..    5525    5923 ..    5524    5924 .. 0.88

  Alignments for each domain:
  == domain 1  score: 261.1 bits;  conditional E-value: 5.5e-81
                  HHHHHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEEE CS
  AMP-binding   2 eeqaaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakvli 99 
                  e+q++ +p+k a+     + +lTY el+++++ lA++L+ lGv+ + rVa++ ++s   vva+lailkaG++ vpl+p+ + ++++ +++++e+ ++i
   EEA22218.1 257 EDQVQLNPEKEAVCA--WDGSLTYFELNQQASVLARHLLTLGVRAERRVALCFDKSKWNVVAMLAILKAGGAFVPLDPSHPIARIESLVKEVEVNIII 352
                  789999*******77..789****************************************************************************** PP

                  ETCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHHHHCS CS
  AMP-binding 100 atvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkletrf 197
                    +++   ++l +aa+      +v+++da+ +++ e ++++++ ++ a    +  ++++ + ay+++TSG+TGkPK+ +++h+++++ ++++   +  
   EEA22218.1 353 --CSTGYSSRLVSAAE------HVLCIDAEHMERLEAENIASKHDDLA----T--STNSTNAAYVLFTSGSTGKPKATVIEHQAFCSGAHAH--GPVL 434
                  ..87766888877776......59*******99999999988776543....3..4789*****************************9997..3344 PP

                  CCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEEEESS-E CS
  AMP-binding 198 klkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvllggepl 295
                   +++d++vl+++   ++++l +e l++l++Ga+v++++++++l+   ++ +i++l+v++ +++P++++ l+ +          d + +  ++l+ge+l
   EEA22218.1 435 LIESDSRVLQFAAHTFDASL-VESLTPLMRGACVCIPSEESRLN--GIVSAINELRVNHGFLTPSFVRFLTPA----------DVPNITRLVLAGEAL 519
                  45689**************8.*****************999977..368*********************887..........6777666678***** PP

                  BHHHHHHHHHHHTCEEEEEEEEGGGSSECEE.CHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBE.ETTSEEEEEEEETTS-SEBTT-HHHHHHHEE. CS
  AMP-binding 296 spellrffralfgeevlegYGlTEttgvvtv.lpleedkkklgsvGkplpgvevkivDeetgepv.pdgeeGellvrgpgvmkgYlkkpeataeafd. 390
                   ++ ++ ++++   ++++gYG+TE ++++++ ++  ++++    +G+p+ gv++ +vD+e+   + p g +Gell+ gp+++++Yl++pe+ta++f+ 
   EEA22218.1 520 TQANIKTWSSI---KLINGYGPTESSVAAVInAN-ITEETASHDIGFPV-GVRCWVVDPEDHDVLlPVGCTGELLLEGPSLARCYLNNPEKTAQSFIf 612
                  **********9...59*************88545.444456678****5.********996555469*****************************96 PP

                  E............TCCEEEEEEEEEEE.TTSEEEEEEECCCEEEE CS
  AMP-binding 391 s............egrwlrTGDlgrld.edGyleivgRkkdlikl 422
                  +            + r+++TGDl+r++ e G++ +vgRk+ ++k 
   EEA22218.1 613 NpswsqetginigQCRFYKTGDLVRYNsEAGSFDFVGRKDTQVKY 657
                  2578899***986456**********6266*************96 PP

  == domain 2  score: 254.3 bits;  conditional E-value: 6.5e-79
                   HHHHHHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTES CS
  AMP-binding    1 leeqaaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseak 96  
                   +++q++  p+++a+     +  +TY+++d+ ++rl+ +L + Gv +++ Va++ ++s+  ++a++a+lkaG+++vpl+++ ++++l+  + +++a+
   EEA22218.1 1800 FKQQVRLSPEAPAICA--WDGEFTYSQVDSMSTRLSYYLINFGVMPESFVALCFDKSAYTIIAMIAVLKAGGACVPLDAGHPKAALELRVLETGAQ 1893
                   68999999******77..7789************************************************************************** PP

                   EEEETCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHH CS
  AMP-binding   97 vliatvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslk 192 
                   v++   +    + l+++        + + +  de l+++ ++++         p +  e++p++ a++i+TSG+TGkPKGV+l+hrnlv+++a++ 
   EEA22218.1 1894 VVL--SSPSRTHLLDDV--------VPYAIPVDETLFTQIEDID---------PFDITEASPENAAFVIFTSGSTGKPKGVVLEHRNLVTSAAAHG 1970
                   ***..322222222222........2333333344444222222.........34566799******************************99963 PP

                   HHHCSCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEE CS
  AMP-binding  193 letrfklkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlv 288 
                        +++e+ ++l++++++++ +l  e++++l++G++v+++++d++++   l++++++l v++   + +v+  l  s          d ++l+ +
   EEA22218.1 1971 --ASIGIDESTRILQFASYSFDNSL-EEIFTTLMRGGCVCVPSEDDRMN--NLAKAMNDLDVNFADMTATVAAFLNPS----------DVPKLKGL 2051
                   ..335677899*************8.***************99998844..689*********999988888877445..........77889999 PP

                   EEESS-EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBEETTSEEEEEEEETTS-SEBTT-HHH CS
  AMP-binding  289 llggeplspellrffralfgeevlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeetgepvpdgeeGellvrgpgvmkgYlkkpea 384 
                    +gge++ +e+++ + +++  ++ ++YG+TE+++  +++p+ +  + +  +G+++ +v + +   +++++vp g  Gell+ gp +++ Yl +pe+
   EEA22218.1 2052 AIGGEAPTKEIMETWCSVL--RLQNIYGPTECSINSCHNPDVGVSSDVTNIGRAVGCVSWVVDANDHNNLVPIGCIGELLIEGPILARHYLHNPEK 2145
                   99****************9..49*************99887888889999*********99997778***************************** PP

                   HHHHEEE....................T.CCEEEEEEEEEEETTSEEEEEEECCCEEEE CS
  AMP-binding  385 taeafds....................e.grwlrTGDlgrldedGyleivgRkkdlikl 422 
                   t+++f++                       r+++TGDl+r++ dG+l ++gRk+ +ikl
   EEA22218.1 2146 TQQSFIEdpsfmvslaeknvdttmfppTgHRMYKTGDLVRYNSDGSLVYLGRKDTQIKL 2204
                   ******8899***************962346***************************8 PP

  == domain 3  score: 239.8 bits;  conditional E-value: 1.6e-74
                   HHHHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHH.HTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESE CS
  AMP-binding    3 eqaaktpdkvalvdsgegqtlTYreldervnrlAagLr.slGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakv 97  
                   ++ + +pd+ a+ +   + t+TY++l + +++lA++Lr  +G  k++ + i+ ++s    +++la++kaG + vp++p+ ++++ + i++d +akv
   EEA22218.1 2889 DNIQSHPDALAIDS--WDGTFTYQQLGRYATALAHHLRnLIGKDKEQFIPICFEKSSFAAISMLATMKAGYAFVPIDPQHPKARRQEIISDIDAKV 2982
                   67899*******65..7789******************878******************************************************* PP

                   EEETCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHH CS
  AMP-binding   98 liatvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkl 193 
                   ++  ++ +    + ++++   +v + + +d + ll     +e ++            + ++++ ay+i+TSG+TGkPKG++++h+ +++ + +   
   EEA22218.1 2983 IL--CSPQY---VSSCQE---VVNHAVAVDMNLLLSL---PEPKK---------ALGKYDSSTAAYVIFTSGSTGKPKGCIIEHAGFCSGAVK--N 3056
                   **..87766...444443...4555666665443332...22221.........12245789***************************9888..3 PP

                   HHCSCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEE CS
  AMP-binding  194 etrfklkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvl 289 
                    + f+++++++vl+++++ +++++ le+l++l+ G++ ++++++++l+   ++++i++ +v++  ++P++++ +             + + l+ + 
   EEA22218.1 3057 GPAFSFSPTSRVLQFASYTFDASI-LEILTVLVMGGCTCIPHESTRLN--GIAKFINEKNVNTALLTPSMAQTINPT----------EVPYLQNLA 3139
                   6679999****************7.***************99998877..4789********************555..........445578877 PP

                   EESS-EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTT.SCBEETTSEEEEEEEETTS-SEBTT-HHH CS
  AMP-binding  290 lggeplspellrffralfgeevlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeet.gepvpdgeeGellvrgpgvmkgYlkkpea 384 
                   l+ge++ p+ +  + + +  ++++gYG+TEt++v+++ p+++ ++  + +G+p+ +  + ivD+ +  +++p g  Gell+ gp++++gYl+++e+
   EEA22218.1 3140 LVGEAMTPNHIALWANEL--QLINGYGPTETSIVAATKPRMTLETDSSNIGTPVGN--AWIVDPRNhDRLMPIGAIGELLIEGPTLARGYLNNEEK 3231
                   788888888887777776..59*************88666666667889****977..88888865156669************************ PP

                   HHHHEEE...........T.CCEEEEEEEEEEETT..SEEEEEEECCCEEEE CS
  AMP-binding  385 taeafds...........e.grwlrTGDlgrlded..GyleivgRkkdlikl 422 
                   t+e+f+            +  r+++TGDl+++ +d  G+l +vgRk+ + kl
   EEA22218.1 3232 TREVFIRnptwsiiagspQvRRMYKTGDLVKYAPDnsGELLYVGRKDSQAKL 3283
                   ******778999****975677*********966546***********9987 PP

  == domain 4  score: 241.5 bits;  conditional E-value: 4.8e-75
                   HHHHHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESE CS
  AMP-binding    2 eeqaaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakv 97  
                   eeqa+++p  +  v  + + ++TYreld+++nrlA++L s G++++  V ++ ++s+  +va +a+lkaG++ v l+pt ++++l+ ++e+++ +v
   EEA22218.1 4428 EEQARTRPALTQAVE-AWDAKFTYRELDSHANRLANVLVSQGIGPEVIVPLCFDKSAWAIVAQIAVLKAGGAFVSLDPTHPEDRLKSLIEEVNGRV 4522
                   678888885555555.57899******************99******************************************************* PP

                   EEETCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHH CS
  AMP-binding   98 liatvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkl 193 
                   ++   ++++ +k+ ++ ++     ++iv d+ + l  ++l++ +    +   p++  +++p + ayii+TSG+TGkPKG +++h+++++ + ++  
   EEA22218.1 4523 VL--SSAQQYDKISKIVPN-----TIIVNDR-S-L--SRLPQVT---YS---PRT--SVSPTNSAYIIFTSGSTGKPKGTVIEHGQFCTGALAHG- 4598
                   **..454555666666653.....4555553.2.2..3355444...22...334..489******************************99963. PP

                   HHCSCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEE CS
  AMP-binding  194 etrfklkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvl 289 
                        ++++ + ++++ + +++++ l++l++l+ G+++++++ +++++   +++ i++l+++ ++ +P+v+  l      +      + + ++++ 
   EEA22218.1 4599 -AALHMNSETRSYQFANYTFDASI-LDILTVLILGGCICVPDAEERMN--DVAGSITRLSANWMCITPSVASTLKP----E------SIPTMKVIA 4680
                   .346677899*************7.***************99888833..478********************933....3......67899**** PP

                   EESS-EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEE.......CHCTTTCTSTTS-BEE-TTEEEEEE-TTT.SCBEETTSEEEEEEEETTS-SE CS
  AMP-binding  290 lggeplspellrffralfgeevlegYGlTEttgvvtv.......lpleedkkklgsvGkplpgvevkivDeet.gepvpdgeeGellvrgpgvmkg 377 
                   +gge++ p +++++++ + + ++e+YG++E+++v++           +  +  +  +Gk++ g +  +vD+++ +++vp g  Gel++ g+ v +g
   EEA22218.1 4681 MGGEKMTPGAIEKWSKSV-C-LVEAYGPSECAVVCAAgdkvdqsG--QIVNFDPAVIGKAV-GSRSWVVDQHNcNRLVPVGAIGELMIEGHIVGRG 4771
                   *****************8.5.9*************8777766431..23333455678996.77888888876256779***************** PP

                   BTT-HHHHHHHEEE...............T.CCEEEEEEEEEEETTSEEEEEEECCCEEEE CS
  AMP-binding  378 Ylkkpeataeafds...............e.grwlrTGDlgrldedGyleivgRkkdlikl 422 
                   Yl+++++t+eaf++               +  r++rTGDl+r++edG l ++ R + +ikl
   EEA22218.1 4772 YLNNEKKTKEAFIQdpiwaadarlngliaPrTRMYRTGDLVRYNEDGMLTYIARMDMQIKL 4832
                   *************889999*********85578***************************8 PP

  == domain 5  score: 260.4 bits;  conditional E-value: 9e-81
                   HHHHHHSTTSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-EEEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESE CS
  AMP-binding    2 eeqaaktpdkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdrVaillpnspewvvallailkaGavvvplnptltaeelayiledseakv 97  
                   + ++ ++pd++a++    +  lTY el++ +++lAa+LrslGv+++  V ++l++s+  +v+++a+l+aG+++vpl+p+ + ++ + i+++ +  +
   EEA22218.1 5525 KSRCMEQPDAPAVHA--WDGDLTYTELNKYASSLAAYLRSLGVQPEALVPLCLDKSAWTIVSMYAVLMAGGAIVPLDPSHPLDRHREIVKQIGTDI 5618
                   678889*******88..7889*************************************************************************** PP

                   EEETCTCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEHHHHHHHHHHHHH CS
  AMP-binding   98 liatvdselleklleaaakleavklvivldadellkeeelkeeeeseekaekpeeeeelkpddlayiiYTSGTTGkPKGVmlshrnlvanvaslkl 193 
                   l+  ++s+ ++      ++   v++ i +d+  ++++  l  +  s+     + ++++++++d ay i+TSG+TG+PKG++++h+++ +   ++  
   EEA22218.1 5619 LL--YSSKYNA------KYAGIVQHAISIDESVIRNT--LSRTF-SR-----H-QSRSVRSSDAAYAIFTSGSTGTPKGIIIEHKAFNTGSVAF-- 5695
                   **..6655533......33445566788886555544..33333.22.....2.3456899*************************97775554.. PP

                   HHCSCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHHHHCCCHHCHHHHCCGTT-SEEE CS
  AMP-binding  194 etrfklkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleallesgalkaakkakdlsslrlvl 289 
                       +++++ + l++++l++++++ +e++++l+ Ga++++++++++l+   l+++i++ +vt ++++P+v++ +             + +sl+++ 
   EEA22218.1 5696 GAALQMTSKTRALQFASLSFDAAI-MEIFTTLTLGACICIPSEEERLQ--DLAGTIRRMNVTWTVLTPSVANLIDPV----------SVPSLKVLA 5778
                   5557788999*************7.*****************999955..489*********************332..........5789***** PP

                   EESS-EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEECHCTTTCTSTTS-BEE-TTEEEEEE-TTTSCBE.ETTSEEEEEEEETTS-SEBTT-HHH CS
  AMP-binding  290 lggeplspellrffralfgeevlegYGlTEttgvvtvlpleedkkklgsvGkplpgvevkivDeetgepv.pdgeeGellvrgpgvmkgYlkkpea 384 
                   +gge++spe++ ++++++  +++++YG++E+++v+ + +++ +++ ++ +G  +  +   +v++e+ + + p g  Gel ++gp++ +gYl++  +
   EEA22218.1 5779 SGGEAMSPEVISKWSNKV--HLINAYGPSEASVVALY-NPDVSNNAPNNIGYGIQPTTTWVVNPEDHNQLtPMGSAGELALGGPTLSRGYLGDTVK 5871
                   *****************8..49*************95.5588889999******9999999988766655489999******************** PP

                   HHHHEEE..............TCCEEEEEEEEEEETTSEEEEEEECCCEEEE CS
  AMP-binding  385 taeafds..............egrwlrTGDlgrldedGyleivgRkkdlikl 422 
                   ta af++              ++r   TGDl+++++dG+l ++gRk+ ++kl
   EEA22218.1 5872 TAAAFIDnpswaeefatetcaGQRIHLTGDLVKYRPDGSLDFIGRKDSQVKL 5923
                   ******8899*******9985367***************************8 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.3   0.0   2.8e-14   7.1e-11       2      67 .]     802     866 ..     801     866 .. 0.97
   2 !   47.8   0.0   5.4e-16   1.4e-12       2      65 ..    2348    2410 ..    2347    2412 .. 0.97
   3 !   41.0   0.0   7.2e-14   1.8e-10       2      64 ..    3425    3486 ..    3424    3489 .. 0.97
   4 !   46.7   0.0   1.2e-15     3e-12       2      64 ..    4979    5040 ..    4978    5042 .. 0.96
   5 !   34.6   0.1     7e-12   1.8e-08       2      65 ..    6063    6125 ..    6062    6127 .. 0.96
   6 !   46.0   0.2     2e-15     5e-12       1      64 [.    7157    7219 ..    7157    7221 .. 0.96
   7 !   21.9   0.0   6.6e-08   0.00017       2      59 ..    7755    7818 ..    7754    7826 .. 0.87

  Alignments for each domain:
  == domain 1  score: 42.3 bits;  conditional E-value: 2.8e-14
  PP-binding   2 klrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaayl 67 
                  lr+l+++vl++pl+  ++++++ +lG+DS++a++ +++ +++ g+ +++ d++  ++++ela+y+
  EEA22218.1 802 SLRQLWSDVLNIPLSKTSLHHSFLSLGGDSITAMTCMNRCKQR-GIGLTVQDILRSTSIRELAKYV 866
                 59**************99************************9.*******************997 PP

  == domain 2  score: 47.8 bits;  conditional E-value: 5.4e-16
  PP-binding    2 klrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaa 65  
                   l++l++++l v+++ i++d+++f  G+DS++a++l+aa +++ g +i+++d+f+ p l+e+a+
  EEA22218.1 2348 VLQNLWSTLLSVDASNISADDTFFRHGGDSISAMRLVAAARRQ-GYSISVADIFQAPKLSEIAQ 2410
                  699****************************************.******************98 PP

  == domain 3  score: 41.0 bits;  conditional E-value: 7.2e-14
  PP-binding    2 klrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaela 64  
                  +lr+++a+vl++++e+i++d ++  +G+DS++a++++++ + + ++ ++++ + ++++++ la
  EEA22218.1 3425 TLRDIWASVLKLSTESISLDRSFLHMGGDSMSAMAVMSRCRTQ-NLGVTVENIITCKSIRKLA 3486
                  69*****************************************.****************997 PP

  == domain 4  score: 46.7 bits;  conditional E-value: 1.2e-15
  PP-binding    2 klrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaela 64  
                  +l+ l++evl vp  +i+ d+++f lG+DSl+a++l++  + + g+++++ d+f hptl+e++
  EEA22218.1 4979 TLQGLWEEVLAVPKTSIGSDDSFFRLGGDSLAAMRLVGIARSR-GISLSVVDIFRHPTLEEMS 5040
                  5899***************************************.*****************97 PP

  == domain 5  score: 34.6 bits;  conditional E-value: 7e-12
  PP-binding    2 klrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaa 65  
                  +lre++ +vl+ p+e ++++ ++ +lG+DS++a++++++ +++ +++++l d++  ++l  la+
  EEA22218.1 6063 TLREIWGQVLNQPAEKVNLNRSFLSLGGDSITAMAVVSRSRRQ-DIKVTLHDILRSSSLIKLAE 6125
                  69*************************************9999.**************999986 PP

  == domain 6  score: 46.0 bits;  conditional E-value: 2e-15
  PP-binding    1 eklrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaela 64  
                  ekl++l+++ lg+pl++i+ d+++fdlG+DS++a++l++  ++e g+ ++++d+f +p  +++a
  EEA22218.1 7157 EKLLRLWSDKLGLPLDSITKDDSFFDLGGDSITAMALVGDARDE-GLILTVADVFRNPVFKDMA 7219
                  589*****************************************.*************999887 PP

  == domain 7  score: 21.9 bits;  conditional E-value: 6.6e-08
  PP-binding    2 klrelvaevlgv...plee....idpdtdlfdlGlDSllavellaaleeefgveiplsdlfehpt 59  
                   lr+++++vlg    + e+    i+pd+++f+lG+D + +++++  le+e ++++ l+dl e pt
  EEA22218.1 7755 VLRRAWEQVLGDtsnNNEDvpppIKPDSSFFSLGGDLIGLAQVAWLLEQE-DFKVRLDDLIERPT 7818
                  7999*******9888333344558**************************.*********99887 PP

>> AMP-binding_C  AMP-binding enzyme C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0       1.2     3e+03       1      74 [.     666     758 ..     666     760 .. 0.57
   2 !   10.8   0.0   0.00029      0.76      23      76 .]    2239    2310 ..    2232    2310 .. 0.80
   3 !    8.1   0.0    0.0021       5.3      43      76 .]    3350    3383 ..    3292    3383 .. 0.71
   4 ?    5.1   0.0     0.018        47      43      76 .]    4907    4940 ..    4895    4940 .. 0.91
   5 !    6.8   0.0    0.0052        13      41      76 .]    5979    6023 ..    5932    6023 .. 0.61

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 1.2
                    HHHHHHHSSTTEEEEEEE-----TTS...---EEEEEE---.....---...............HHHHHHHHHHHHT-TTTS-SEEEE-S---B-T CS
  AMP-binding_C   1 evEsalvshpaVaeaaVvGvpdevkG...ealvafVvlkdg.....sea...............leeeLkahvrkelgpyavpkkvvfvdelpktr 73 
                    e+Es l++hp  +   V   p +  G   + lva+   +++     + a                  ++++ +++ l++y+ p+   +++++p  +
     EEA22218.1 666 EIESNLIKHPTLKHGLVL-LPKA--GpaaQKLVAIMSFSEDsigdlP-AnpsplkvldipnrqgYISAIREAMATILPTYMIPSIWLCIEAFPVLT 757
                    566666666666666666.2222..2223666666665322122221.122334445555555667889999999999999999888888888655 PP

                    T CS
  AMP-binding_C  74 s 74 
                    s
     EEA22218.1 758 S 758
                    5 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00029
                     -TTS---EEEEEE---..---.................HHHHHHHHHHHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   23 evkGealvafVvlkdg..sea.................leeeLkahvrkelgpyavpkkvvfvdelpktrsGK 76  
                     e++ ++lvafV l+++  + +                 +  ++k+ + +++ +y+vp+  + v+ +p+t sGK
     EEA22218.1 2239 ETTSKVLVAFVCLQSDskK-PtqsdadfilsmtqsfqsIVLNVKSEISSQIQSYMVPNVYIPVSCFPMTSSGK 2310
                     455689*******644331.23345678888888888888999999999***********************9 PP

  == domain 3  score: 8.1 bits;  conditional E-value: 0.0021
                     HHHHHHHHHHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   43 eeeLkahvrkelgpyavpkkvvfvdelpktrsGK 76  
                      + +++++r+++++y++p++ v+++ lp+  sGK
     EEA22218.1 3350 LHLIQDRLREKVPAYMTPSTWVILQHLPLLPSGK 3383
                     45688999*************************9 PP

  == domain 4  score: 5.1 bits;  conditional E-value: 0.018
                     HHHHHHHHHHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   43 eeeLkahvrkelgpyavpkkvvfvdelpktrsGK 76  
                      e L++ v+k l++y+ p+ +  v+ +p t+sGK
     EEA22218.1 4907 VESLEKSVAKVLPSYMIPQLFFPVSIIPFTTSGK 4940
                     48899****************************9 PP

  == domain 5  score: 6.8 bits;  conditional E-value: 0.0052
                     -.........HHHHHHHHHHHHT-TTTS-SEEEE-S---B-TTS- CS
  AMP-binding_C   41 a.........leeeLkahvrkelgpyavpkkvvfvdelpktrsGK 76  
                     +             +k+ ++++l++y+ p++  +v+++p+  sGK
     EEA22218.1 5979 EtcqlvekneELSRIKDNLTSQLPSYMIPQAWAVVNAIPMLVSGK 6023
                     023333333335778999999*******************99998 PP

>> Transferase  Transferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.7   0.0   0.00048       1.2     107     193 ..    1441    1526 ..    1436    1561 .. 0.82
   2 ?   -3.6   0.0       1.3   3.2e+03     149     177 ..    3627    3655 ..    3588    3667 .. 0.82
   3 !    7.8   0.0   0.00044       1.1      82     169 ..    6677    6768 ..    6670    6774 .. 0.76

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00048
  Transferase  107 kklepddslenllpqlavkkegeaipllavqvTkfkcGgvalgvsvsHaiaDgaSlktfieswaelargekkvtvtplfarelllpr 193 
                   +++ ++d ++ +l    ++++    pl  + +   + G v+    +sH i+Dg S++ +++++ +   g+ + + +plf     + +
   EEA22218.1 1441 LRCTDEDNVQTVLDIHPMQPNR-RKPLHQFTICVTETGKVFCRLELSHVIMDGVSISIMLRDLEKAYSGNLQTSPKPLFSNFVSYLQ 1526
                   6788999999999866666666.5599888888889*********************************999999999988666655 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 1.3
  Transferase  149 gvsvsHaiaDgaSlktfieswaelargek 177 
                    ++  H ++D  S   +++++ +l +g +
   EEA22218.1 3627 FICAHHLVVDVISWGIIVQDLEDLLQGRQ 3655
                   5899*******************999983 PP

  == domain 3  score: 7.8 bits;  conditional E-value: 0.00044
  Transferase   82 rlelsCndeGadFveAeadveLsdlkkle..pddslenl....lpqlavkkegeaipllavqvTkfkcGgvalgvsvsHaiaDgaSlktfiesw 169 
                    ++++ + +G  F +A   +  sd++++e  ++++l++l    l+++++  +++    l v vT   +G v++ + v+Ha++Dg S   +i+++
   EEA22218.1 6677 TVFVNSTYKGSSFDQAVLHNVDSDVIHVEcdDSVVLAQLqsisLYERNARRKQKIPHQLTVCVT--PSGRVFMKIEVNHAVIDGGSTPILIHDL 6768
                   6788888899999999999999999998887888888883333344444444433334666666..69******************99999876 PP

>> DUF600  Protein of unknown function, DUF600
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0      0.93   2.4e+03      48      86 ..    2483    2519 ..    2475    2529 .. 0.79
   2 ?    6.5   0.1    0.0031       7.9      34      97 ..    3511    3574 ..    3501    3606 .. 0.77
   3 ?   -1.6   0.0         1   2.6e+03      60      92 ..    5120    5152 ..    5111    5178 .. 0.78
   4 ?    1.3   0.0      0.13   3.2e+02      35     113 ..    6152    6229 ..    6140    6236 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.93
                  EEEGGGGGGT--S-HHHHHHHHHHHHHHHHHHHHHHHHH CS
      DUF600   48 liysheipekynvseeeykkllkeLyelikeLreefkke 86  
                  + + +++p+++n++   +k  +++Ly+  + Lr+ + ++
  EEA22218.1 2483 TQNIYDLPDSINIE--RFKAAWQRLYQNESILRTRILHS 2519
                  56889999999996..6**********999999876555 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0031
                  -EEEEEEEEETTT-EEEGGGGGGT--S-HHHHHHHHHHHHHHHHHHHHHHHHHHSS--SEEEEE CS
      DUF600   34 gevyFyylkkesekliysheipekynvseeeykkllkeLyelikeLreefkkeeqeaWtnltlt 97  
                  +++yF  ++ +++++++s+ i  + +vs+++ ++ +++L+++ ++Lr  f++  +  W++  l+
  EEA22218.1 3511 QSLYFRCMSGQTSHFNQSIMIDLTSSVSNDQVQSAMSKLVSVHSMLRARFSRDGNGIWKQRILQ 3574
                  5677777777779*********************************************987665 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 1
                  S-HHHHHHHHHHHHHHHHHHHHHHHHHHSS--S CS
      DUF600   60 vseeeykkllkeLyelikeLreefkkeeqeaWt 92  
                  v+ +++k+++++L++ ++ Lr+ + ++ + +  
  EEA22218.1 5120 VDINQFKDSWQQLVDEFDILRTRIPHTASSEFL 5152
                  88899****************998777766554 PP

  == domain 4  score: 1.3 bits;  conditional E-value: 0.13
                  EEEEEEEEETT.T.-EEEGGGGGGT--S-HHHHHHHHHHHHHHHHHHHHHHHHHHSS--SEEEEEEETTS-EEEEEE---- CS
      DUF600   35 evyFyylkkes.e.kliysheipekynvseeeykkllkeLyelikeLreefkkeeqeaWtnltltlkksGklkieydyddl 113 
                  ++yF   k ++ +  +++s+ ++ + ++s +  ++ l+ +++  ++Lr  fk + + +W++   +++++ +++  + y+ +
  EEA22218.1 6152 QMYFLTAKGHQgSsRFNQSYTLRLSRHLSADRVQSALRAIVSSQSMLRARFKLNATGEWEQ---QISSDTEFSFRFRYHRI 6229
                  5566555544443489999999999999*******************************87...45555568888888765 PP

>> DUF5122  Domain of unknown function (DUF5122) beta-propeller
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       1.4   3.5e+03      23      33 ..     635     646 ..     633     646 .. 0.93
   2 ?    4.8   0.1     0.014        35      23      32 ..    2183    2192 ..    2180    2192 .. 0.93
   3 ?   -0.3   0.0      0.54   1.4e+03      23      32 ..    4811    4820 ..    4807    4820 .. 0.87
   4 ?    1.5   0.1      0.14   3.7e+02      23      33 ..    5902    5912 ..    5899    5912 .. 0.94

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 1.4
     DUF5122  23 lvRLna.DGslD 33 
                 lvR+n+  Gs+D
  EEA22218.1 635 LVRYNSeAGSFD 646
                 8********999 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.014
     DUF5122   23 lvRLnaDGsl 32  
                  lvR+n+DGsl
  EEA22218.1 2183 LVRYNSDGSL 2192
                  8********8 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.54
     DUF5122   23 lvRLnaDGsl 32  
                  lvR+n DG l
  EEA22218.1 4811 LVRYNEDGML 4820
                  8*******65 PP

  == domain 4  score: 1.5 bits;  conditional E-value: 0.14
     DUF5122   23 lvRLnaDGslD 33  
                  lv++ +DGslD
  EEA22218.1 5902 LVKYRPDGSLD 5912
                  89********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (7901 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       561  (0.0312901); expected 358.6 (0.02)
Passed bias filter:                      518  (0.0288917); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 2.42u 0.36s 00:00:02.78 Elapsed: 00:00:00.60
# Mc/sec: 39559.20
//
Query:       EEA22219.1  [L=405]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.3e-08   31.6   0.0    1.4e-07   31.0   0.0    1.3  1  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
    0.00014   21.9   0.0     0.0011   18.9   0.0    2.4  2  NAD_binding_9  FAD-NAD(P)-binding
    0.00026   20.3   0.0    0.00066   18.9   0.0    1.7  2  K_oxygenase    L-lysine 6-monooxygenase (NADPH-requiring)
     0.0051   16.1   0.0        0.5    9.6   0.0    2.8  3  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase


Domain annotation for each model (and alignments):
>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.0   0.0   3.2e-11   1.4e-07       3     252 ..      11     339 ..       9     351 .. 0.68

  Alignments for each domain:
  == domain 1  score: 31.0 bits;  conditional E-value: 3.2e-11
                  EEEE--SHHHHHHHHHHHHH.TS-EEEEE..........TTHCHHHCSHHHHCHHHHHHHHHHHHH................................ CS
                  xxxxxxxxxxxxxxxxxxxx.xxxxxxxx..........xxxxxxxxxxxxxxxxxxxxxxxxxxx................................ RF
  Pyr_redox_2   3 vvviGgGpAGlaaaltlaqa.gakvtlve..........legtclnggcllskallgvaedaeias................................ 57 
                   vv+G+GpAG+a+  +l +    +++ ++          +              +++v++++++                                  
   EEA22219.1  11 AVVVGAGPAGVAVLGNLLELgLTRIAWIDpvfdggrinsK--------------YREVPSNTKVSFfrsyatgfqpfrniaqaastpnafsvmnkldq 94 
                  69*****************626688888555443333332..............3333333333223333334455555555999999999******* PP

                  ..........HHHHCHHHHCCCCHCCTCEEEEESCEEEEETEEEC............TCEEEEEESEEEE---EEE-BCTCTTC.TTBEECCSECHHH CS
                  ..........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  58 ..........evvkklnqgielllgeevvkidpgkkkvklekkke............gdeekiaydklvlAtGssprdlgipGvaenvgklvrtldsa 133
                            e +k l++g+ +++++++ + +  +++++++  k+            + + +i   +l+l+tGsspr l+ p     v ++ +++++ 
   EEA22219.1  95 detcslhyaaEMIKDLTAGLLKMKQVSAYRGEVMSATYEDN--KSrwkvrihspdpsSANIEISTPRLILCTGSSPRSLPSPSP--SV-TG-SSSTKL 186
                  *******9997778888887777773333333333333333..33567888888888888999****************66644..11.22.344444 PP

                  HHHCCSS-T..............SEEEEES-SHHHHHHHHHHHHHT-................E.EEEEESSSSSS..TTS-HHHHHHHHHHHHHTTE CS
                  xxxxxxxxx..............xxxxxxxxxxxxxxxxxxxxxxxx................x.xxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 134 ealklkllp..............krivvvGgGyiGvElAaalaklgk................e.vtlveardrll..raldkelsaaleealekeGv 198
                  e+l+l+ +                 ++v+Gg+  ++   + l +l++                + +  +e + +l+   +l+ +++++++e+le++  
   EEA22219.1 187 EELNLDTVLkpsllctviprdepITVAVIGGSHSAILAIMNLVDLAQtthpkmrlkwftrnplKyAEFMEGGWILYdnTGLKGKAAQFAREQLEDSQL 284
                  44444444344555599999988899*******************99566666666666655533557777777777777789999999999999977 PP

                  .EEEESCEEEEEEETTEEEE.EEETTSCEEEESEEEE-S-EEES-HHCS.HCCT-EE CS
                  .xxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxx RF
  Pyr_redox_2 199 .evklgtsvkeidgngekle.vvledgeeidadlvvvavGvrpstelle.eklglel 252
                   + + g ++++id  ++ ++  +  + +  ++  vv+a+G++ ++   e  + g+++
   EEA22219.1 285 pNSVAGRVIEKIDTSDR-AReEEIYQSKLPECTHVVYAIGYERNPLP-ElSRNGVPI 339
                  34566777888887776.2223334444489**********999744.456667666 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.0   2.5e-07    0.0011       1     154 [.      12     165 ..      12     167 .. 0.78
   2 ?   -0.4   0.0      0.22   9.9e+02       1      31 [.     213     244 ..     213     253 .. 0.78

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 2.5e-07
  NAD_binding_9   1 aivGaGprGlavlerLlarakkkspleitlfdpsepgagrvwrtdqseelllNvpasemslftddpptfaeWlrerga.lee...aeeldpddfvp 92 
                    ++vGaGp+G+avl +Ll+       ++i  +dp   g gr+ ++   +e+  N+++s    ++   + f++ +++ +  +     +++ld+d+ ++
     EEA22219.1  12 VVVGAGPAGVAVLGNLLEL----GLTRIAWIDPVFDG-GRINSKY--REVPSNTKVSFFRSYATGFQPFRNIAQAASTpN-AfsvMNKLDQDETCS 99 
                    69*****************....599*******9999.9999998..678999999999999888888888888887641.256688999998887 PP

  NAD_binding_9  93 RalyGrYlrdlfeellarlpegvtvevhraevvdleeradg..qavll......adgaslaadaVvLAlG 154
                         +Y ++++++l+a l +  +v+ +r+ev + + ++++  ++v+       + + ++   +++L++G
     EEA22219.1 100 L----HYAAEMIKDLTAGLLKMKQVSAYRGEVMSATYEDNKsrWKVRIhspdpsSANIEISTPRLILCTG 165
                    5....7999999999999988899*********9998886633455552233211222367777888877 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.22
  NAD_binding_9   1 aivGaGprGlavlerLlara.kkkspleitlf 31 
                    a++G+  ++++++ +L++ a  ++ +++++ f
     EEA22219.1 213 AVIGGSHSAILAIMNLVDLAqTTHPKMRLKWF 244
                    79****************99555555776665 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.1      0.48   2.2e+03     195     211 ..      12      28 ..       7      38 .. 0.64
   2 !   18.9   0.0   1.5e-07   0.00066     109     226 ..     117     248 ..     112     305 .. 0.79

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.48
  K_oxygenase 195 aVvGsGqSaaeifedll 211
                  +VvG+G  +  ++ +ll
   EEA22219.1  12 VVVGAGPAGVAVLGNLL 28 
                  56677766666666665 PP

  == domain 2  score: 18.9 bits;  conditional E-value: 1.5e-07
  K_oxygenase 109 leeqvrfgeeveevepdeeeeeelltveskdaegeeeelearnlvlgvGtep.kiPevleklegkervvHsseylerkee..............llak 191
                  +++  ++  ev++ ++++++++  ++++s d++  + e+++ +l+l +G++p ++P+   +++g +  +  +e+                    + ++
   EEA22219.1 117 MKQVSAYRGEVMSATYEDNKSRWKVRIHSPDPSSANIEISTPRLILCTGSSPrSLPSPSPSVTG-SSSTKLEELN----LdtvlkpsllctvipRDEP 209
                  55667899**********99889999**999******************776379999998885.3333333322....1223357788988889999 PP

  K_oxygenase 192 kriaVvGsGqSaaeifedllrr....qkkvelklvtrse 226
                   ++aV+G+  Sa   +++l++      +k+ lk++tr++
   EEA22219.1 210 ITVAVIGGSHSAILAIMNLVDLaqttHPKMRLKWFTRNP 248
                  ************988887766532234469999999975 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.0   0.00011       0.5       1      69 [.      12      83 ..      12     120 .. 0.70
   2 ?    2.9   0.0     0.012        52     167     187 ..     212     232 ..     208     251 .. 0.83
   3 ?   -1.0   0.0      0.19   8.4e+02     234     269 ..     292     326 ..     266     342 .. 0.66

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00011
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledyl....ilEkgnignsiyrypkemtfispsftsekleipdlnaiseets.p 69
                 +++GaGPaG+a+  +l ++gl+++     + + g+i   +++ p ++++ s  f+s   +++ + +i++ +s p
   EEA22219.1 12 VVVGAGPAGVAVLGNLLELGLTRIAwidpVFDGGRINSKYREVPSNTKV-S-FFRSYATGFQPFRNIAQAAStP 83
                 79**********9999999998876334466788888888888888876.3.4667777777777777666533 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.012
  Pyr_redox_3 167 vvViGgknSavDaAlelvrkg 187
                  v+ViGg+ Sa+ a ++lv+  
   EEA22219.1 212 VAVIGGSHSAILAIMNLVDLA 232
                  89*********9999999874 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 0.19
  Pyr_redox_3 234 evkeikekeeeykvktedgkkvevkddvvlatGykp 269
                   +++i+++++  + ++  ++k+ + + vv+a+Gy+ 
   EEA22219.1 292 VIEKIDTSDRARE-EEIYQSKLPECTHVVYAIGYER 326
                  4555555444333.3333356667777778888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (405 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       445  (0.0248201); expected 358.6 (0.02)
Passed bias filter:                      429  (0.0239277); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.60u 0.26s 00:00:00.86 Elapsed: 00:00:00.50
# Mc/sec: 2449.16
//
Query:       EEA22220.1  [L=1180]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
      0.004   17.8   1.2      0.004   17.8   1.2    3.6  3  FOXP-CC    FOXP coiled-coil domain
     0.0053   17.1  22.8       0.56   10.8   1.2    4.6  4  zf-C2H2    Zinc finger, C2H2 type


Domain annotation for each model (and alignments):
>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.4     0.046   4.1e+02       6      32 ..     800     829 ..     799     832 .. 0.90
   2 !   17.8   1.2   4.4e-07     0.004       6      41 ..     834     869 ..     831     874 .. 0.90
   3 ?   -0.3   0.2      0.19   1.7e+03      12      28 ..     912     928 ..     907     932 .. 0.89

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.046
     FOXP-CC   6 vCkWPgC...ekvledveeflkhlnseHal 32 
                 +C  P+C    k ++  ++ ++h  + H++
  EEA22220.1 800 TCTFPDCvgePKSFKRKADWVRHETERHRH 829
                 6******9888999999********99986 PP

  == domain 2  score: 17.8 bits;  conditional E-value: 4.4e-07
     FOXP-CC   6 vCkWPgCekvledveeflkhlnseHalddkstaqlr 41 
                  C+ P+C++ +   ++f++hl +eH+  d ++ ++r
  EEA22220.1 834 ACNMPNCDHKCFRKNNFVQHLVREHRKPDPTAKKAR 869
                 5*************************9988877665 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.19
     FOXP-CC  12 Cekvledveeflkhlns 28 
                 C +v++d  +++ hl +
  EEA22220.1 912 CGNVCKDWRKLMVHLAR 928
                 99************975 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.1   0.4    0.0019        17       1      20 [.     771     792 ..     771     794 .. 0.95
   2 !    8.8   0.2   0.00027       2.4       1      23 []     799     827 ..     799     827 .. 0.90
   3 !    4.2   2.7    0.0074        67       3      23 .]     835     858 ..     833     858 .. 0.84
   4 !   10.8   1.2   6.2e-05      0.56       3      23 .]     909     929 ..     908     929 .. 0.96

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0019
                 EEETTTT..EEESSHHHHHHHH CS
     zf-C2H2   1 ykCpdCg..ksFkrksnLkrHi 20 
                 ++C+ C   k+F  +s+ ++Hi
  EEA22220.1 771 FECSLCFkvKKFQKPSDWTKHI 792
                 89*******************8 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.00027
                 EEET..TTT...EEESSHHHHHHHHHC.C CS
     zf-C2H2   1 ykCp..dCg...ksFkrksnLkrHirt.H 23 
                 ++C+  dC    ksFkrk + +rH    H
  EEA22220.1 799 FTCTfpDCVgepKSFKRKADWVRHETErH 827
                 899999999999************87666 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.0074
                 ET..TTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   3 Cp..dCgksFkrksnLkrHirt.H 23 
                 C+   C+ ++ rk n+++H+ + H
  EEA22220.1 835 CNmpNCDHKCFRKNNFVQHLVReH 858
                 77789**6666********99888 PP

  == domain 4  score: 10.8 bits;  conditional E-value: 6.2e-05
                 ETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   3 CpdCgksFkrksnLkrHirtH 23 
                 C  Cg ++k++  L++H+ +H
  EEA22220.1 909 CRFCGNVCKDWRKLMVHLARH 929
                 9******************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1180 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       645  (0.0359752); expected 358.6 (0.02)
Passed bias filter:                      387  (0.0215851); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.77u 0.28s 00:00:01.05 Elapsed: 00:00:00.47
# Mc/sec: 7479.15
//
Query:       EEA22221.1  [L=193]
Description: glucosamine 6-phosphate N-acetyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.2e-10   41.7   0.1    1.6e-10   41.2   0.1    1.2  1  Acetyltransf_1   Acetyltransferase (GNAT) family
    3.5e-09   37.0   0.3    5.6e-09   36.3   0.3    1.3  1  Acetyltransf_7   Acetyltransferase (GNAT) domain
      9e-07   28.9   0.1    1.3e-06   28.4   0.1    1.2  1  Acetyltransf_10  Acetyltransferase (GNAT) domain
  ------ inclusion threshold ------
      0.041   14.0   0.2      0.077   13.1   0.2    1.4  1  Acetyltransf_4   Acetyltransferase (GNAT) domain
      0.067   13.3   0.0       0.11   12.5   0.0    1.4  1  Acetyltransf_9   Acetyltransferase (GNAT) domain


Domain annotation for each model (and alignments):
>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.2   0.1   4.5e-14   1.6e-10      14     117 .]      52     160 ..      33     160 .. 0.80

  Alignments for each domain:
  == domain 1  score: 41.2 bits;  conditional E-value: 4.5e-14
                     HHHHHHHHHHHHHHHHSTTC..EEEE.EEET..TEEEEEEEEEEEET...TSTTEEEEEEEEESGGGTTSSHHHHHHHHHHHHHHHTTESEEEEE CS
  Acetyltransf_1  14 ppnedaseeefeesfsleae..gllv.aeed..geliGfisllkipd...ekggvayieslaVspeyrgkGlGsaLlealeerareegikkivla 100
                        ++a++ ++++++  +    +++v + ed  ++++G+ ++        + g  ++ie++ +++++++k  G++L+e+l  +a + g++   l 
      EEA22221.1  52 GDISEAQYLDRFDWHKHHGQgwYYCVvIVEDatDRIVGTGTVVVERKfihNLGISGHIEDISIAKDHQRKHFGQKLIETLDSIAVKVGCYQSILN 146
                     44455566667777555555675555677777899*****999999999966889**********************************555787 PP

                     EETTEHHHHHHHHHTTE CS
  Acetyltransf_1 101 veedndaairlYeklGF 117
                     ++  n    ++Y k+G+
      EEA22221.1 147 CSLAN---AGFYAKCGY 160
                     76667...********8 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.3   0.3   1.6e-12   5.6e-09       4      76 .]      76     162 ..      68     162 .. 0.73

  Alignments for each domain:
  == domain 1  score: 36.3 bits;  conditional E-value: 1.6e-12
                     EEEEEEET.TEEEEEEEEEEES.........TCTEEEEE-GGGTTSSHHHHHHHH...TT..SEEEEE..EEEETHHHHHHHHHHTTEEE CS
  Acetyltransf_7   4 evfVaedd.gkivGfialslld.........aeitrlaVdpeyrgkGiGraLlea...ae..kgiile..qlelnaekaikfYeklGFee 76 
                     +v ++ed  ++ivG+  ++++          ++i+ + +++++++k  G++L+e    ++   g+  +  +  l++   ++fY+k+G+e+
      EEA22221.1  76 CVVIVEDAtDRIVGTGTVVVERkfihnlgisGHIEDISIAKDHQRKHFGQKLIETldsIAvkVGCYQSilNCSLAN---AGFYAKCGYEK 162
                     445555558999988777777778988888777777******************6565224566542223445554...89*******95 PP

>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.4   0.1   3.6e-10   1.3e-06      21     109 ..      64     163 ..      46     169 .. 0.84

  Alignments for each domain:
  == domain 1  score: 28.4 bits;  conditional E-value: 3.6e-10
  Acetyltransf_10  21 alrerieegealllvaeeg..gkivGviel.rdgs.........hisllfVdpeyrgqGigkaLleaveeeaekdgikleltvnaspyavpfYe 102
                       ++++  +g+++++v  e+  ++ivG++++  +++         hi+ + ++++++++  g++L+e++ + a k g   +  +n s +  +fY 
       EEA22221.1  64 DWHKHHGQGWYYCVVIVEDatDRIVGTGTVvVERKfihnlgisgHIEDISIAKDHQRKHFGQKLIETLDSIAVKVGCY-QSILNCSLANAGFYA 156
                      4556666888887777776669***999887666689**********************************9888776.*************** PP

  Acetyltransf_10 103 klGFkav 109
                      k+G+++ 
       EEA22221.1 157 KCGYEKQ 163
                      ****986 PP

>> Acetyltransf_4  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.2   2.1e-05     0.077      24     149 ..      47     175 ..      41     177 .. 0.66

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2.1e-05
  Acetyltransf_4  24 aitfeyevssveefekf..lealdsekeyvflvae..sdrivGyaylg...qfkkr.akdwkaelsvylaerdnnkeglgrelidaleqvl.keq 109
                     a+tf  ++s ++++++f   ++++++  y   + e   drivG+ +++   +f    + +++ e  + +a +d + +  g++li+ l  ++ k  
      EEA22221.1  47 ALTFTGDISEAQYLDRFdwHKHHGQGWYYCVVIVEdaTDRIVGTGTVVverKFIHNlGISGHIE-DISIA-KDHQRKHFGQKLIETLDSIAvKVG 139
                     66666666777777755213333344444444444489******99983222222224444444.46666.78999999999*********4444 PP

  Acetyltransf_4 110 nienllaeiaspnensiqfhkalGFelvgifkkcikkngr 149
                      ++++l +      +++ f+++ G+e+  i+  + +k  r
      EEA22221.1 140 CYQSILNC----SLANAGFYAKCGYEKQSIEMSHLYKETR 175
                     45555555....45899***************99999766 PP

>> Acetyltransf_9  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   3.1e-05      0.11      15     127 ..      44     162 ..      28     163 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 3.1e-05
                     HHHHHHTT----H...HHHHHHHHHHTTS...EEEEEEE.TTEEEEEEEEEEEEEEETTEEEEEEEEEEEEE-CCGTTS-HHHHHHHHHHHHHHH CS
  Acetyltransf_9  15 ellkyaFqdeespl.eeireyfrkllees...rvlgaed.ngelvgqlallplelnvpGktlkaagvtgVavapehrgrgvlskLlaraleemre 104
                      l++  F  + s++ +  r+ ++k  +++    v+++ed  +++vg+ +++  +  +++  +  + + +++ a +h+++++ +kL++++   + +
      EEA22221.1  44 CLQALTFTGDISEAqYLDRFDWHKHHGQGwyyCVVIVEDaTDRIVGTGTVVVERKFIHNLGI-SGHIEDISIAKDHQRKHFGQKLIETLDSIAVK 137
                     3556678777777743447888999998833234455559999***9999987777777444.699***************************99 PP

                     TT--EEEE--..SSHHHHHTTT-EE CS
  Acetyltransf_9 105 egqplsllfP..ssipiYrrfGyei 127
                      g   s+l    +++++Y + Gye+
      EEA22221.1 138 VGCYQSILNCslANAGFYAKCGYEK 162
                     999999999877889********85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (193 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       585  (0.0326287); expected 358.6 (0.02)
Passed bias filter:                      457  (0.0254894); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.47u 0.29s 00:00:00.76 Elapsed: 00:00:00.46
# Mc/sec: 1262.47
//
Query:       EEA22222.1  [L=72]
Description: hypothetical protein PMAA_060010 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (72 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       297  (0.0165653); expected 358.6 (0.02)
Passed bias filter:                      236  (0.013163); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.41u 0.29s 00:00:00.70 Elapsed: 00:00:00.46
# Mc/sec: 474.95
//
Query:       EEA22223.1  [L=770]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
          3    8.5  12.5       0.69   10.6   0.4    3.4  3  FOXP-CC   FOXP coiled-coil domain


Domain annotation for each model (and alignments):
>> FOXP-CC  FOXP coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   2.1    0.0081   1.4e+02       6      35 ..     207     236 ..     204     240 .. 0.88
   2 ?   -0.6   0.1      0.12   2.2e+03      11      34 ..     249     275 ..     242     279 .. 0.76
   3 ?   10.6   0.4   3.8e-05      0.69      10      34 ..     549     573 ..     547     582 .. 0.89

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.0081
     FOXP-CC   6 vCkWPgCekvledveeflkhlnseHalddk 35 
                  C+  gCe+ + + +++ +h +s H+ + +
  EEA22223.1 207 KCEEDGCESRFGNKNDLERHRKSVHNKCPE 236
                 57778********************98765 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.12
     FOXP-CC  11 gC...ekvledveeflkhlnseHaldd 34 
                 +C   ekv   +++f +hl+ +H  ++
  EEA22223.1 249 NCghpEKVWPRLDNFKAHLRLKHYEEN 275
                 55555778888999*****99997665 PP

  == domain 3  score: 10.6 bits;  conditional E-value: 3.8e-05
     FOXP-CC  10 PgCekvledveeflkhlnseHaldd 34 
                 P C k++ ++++f++hl++ H+ + 
  EEA22223.1 549 PQCAKLFLQQKDFVEHLRTVHHAEP 573
                 9********************9875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (770 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       914  (0.0509789); expected 358.6 (0.02)
Passed bias filter:                      391  (0.0218082); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.72u 0.32s 00:00:01.04 Elapsed: 00:00:00.51
# Mc/sec: 4510.10
//
Query:       EEA22224.1  [L=267]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    7.9e-09   34.9  29.8    7.9e-09   34.9  29.8    1.6  2  MFS_1       Major Facilitator Superfamily
    2.8e-06   26.5  11.7    3.6e-06   26.1  11.7    1.1  1  MFS_1_like  MFS_1 like family
  ------ inclusion threshold ------
      0.017   14.2  14.1      0.025   13.6  14.1    1.2  1  PHO4        Phosphate transporter family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.2      0.23   1.4e+03     109     134 ..      35      59 ..      31      60 .. 0.63
   2 !   34.9  29.8   1.3e-12   7.9e-09       2     149 ..     114     261 ..     113     265 .. 0.86

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.23
       MFS_1 109 liadwfpkeergraigllsagfslGa 134
                 l ++ f+  + g a+gl+ +g ++G+
  EEA22224.1  35 LSVQSFSS-RLGTANGLVKLGGAIGV 59 
                 45556665.77777777777777775 PP

  == domain 2  score: 34.9 bits;  conditional E-value: 1.3e-12
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslpl.GrlsdrfGrrrvlllglllfalglllllfa..sslwlllvlrvlqGl 97 
                 +la  +  +  ++++++l+ ++a++ g+s+s+    +++y+ +++++ +++    sd+ G+ ++ll++++l +++ ++++++  s+l+lll++ +l G+
  EEA22224.1 114 FLASGIGLFPLYVTASLLS-YIASSIGLSGST-AVGFAAYFNACMALGYVAsDIASDKAGSTSMLLAAIVLNIIT-TFAIWPisSTLTLLLLFGALNGF 209
                 5666666666777778888.999999999997.5567888888888888886888********************.666654435555*********** PP

       MFS_1  98 gagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg 149
                 + ga++ ++ ++i +   + + + +ig++ +g+ lG++lg+l++g+l++++g
  EEA22224.1 210 ANGAFYITMPTAIDRFLGPGQAAVGIGMYVTGWTLGVLLGALIAGFLIQAAG 261
                 ************************************************7766 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.1  11.7     6e-10   3.6e-06     262     378 ..     146     261 ..     109     264 .. 0.78

  Alignments for each domain:
  == domain 1  score: 26.1 bits;  conditional E-value: 6e-10
  MFS_1_like 262 lGslvalgvvaeiplfffaeklleklGhvklliiallayilr.fllyaiienawlvlpievLhgisfgllwaaaveyvskiapksleatgqgllsglyf 359
                 +G +  + + + +  ++ +    +k G + +l++a+++ i++ f +  i + + l+l++ +L+g++ g+++ ++ + + ++ +++ +a g+g++++  +
  EEA22224.1 146 VGFAAYFNACMALG-YVASDIASDKAGSTSMLLAAIVLNIITtFAIWPISSTLTLLLLFGALNGFANGAFYITMPTAIDRFLGPGQAAVGIGMYVTG-W 242
                 34444444444443.5555666799***********99877516666666999*****************************************975.* PP

  MFS_1_like 360 glGralGsliGGllwdlks 378
                  lG  lG+li+G+l++  +
  EEA22224.1 243 TLGVLLGALIAGFLIQAAG 261
                 ***************9766 PP

>> PHO4  Phosphate transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6  14.1   4.2e-06     0.025      20     137 ..     141     257 ..     124     263 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 4.2e-06
        PHO4  20 tlrqAvilaaifeflGavllGaeVaetirkgivdvelfdpselmlgmlaallgaavwlllatvlglPvStths...lvGaliGaalaa.....eggeav 110
                 +  +Av +aa f+++ a+     Va+ i++              +g +++ll+a+v+++++t+  +P+S+t +   l Gal G+a  a        +a+
  EEA22224.1 141 SGSTAVGFAAYFNACMALGY---VASDIASDK------------AGSTSMLLAAIVLNIITTFAIWPISSTLTlllLFGALNGFANGAfyitmP--TAI 222
                 44555556666655544433...555555554............59***************************44447******9887554330..444 PP

        PHO4 111 kw........kklvkivlswvlsPllggiiaallf 137
                 +          +++  v++w l +llg++ia +l+
  EEA22224.1 223 DRflgpgqaaVGIGMYVTGWTLGVLLGALIAGFLI 257
                 4466655443479999*************998775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (267 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       670  (0.0373696); expected 358.6 (0.02)
Passed bias filter:                      303  (0.0169); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.41
# Mc/sec: 1958.22
//
Query:       EEA22225.1  [L=1535]
Description: serine/threonine-protein kinase ripk4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.9e-57  191.8   8.4      3e-15   56.6   0.0    5.0  6  Ank_2        Ankyrin repeats (3 copies)
    1.4e-34  118.0   3.3    3.2e-08   34.0   0.0    5.6  5  Ank_4        Ankyrin repeats (many copies)
    1.6e-29  101.0  14.4     0.0001   22.6   0.0    9.5  9  Ank          Ankyrin repeat
    4.2e-28   94.3   3.4    0.00052   20.3   0.0    9.5  9  Ank_3        Ankyrin repeat
    3.3e-27   94.2   7.2    5.3e-05   23.4   0.0    7.6  8  Ank_5        Ankyrin repeats (many copies)
      5e-12   45.6   0.4    2.3e-05   23.8   0.0    3.2  3  PNP_UDP_1    Phosphorylase superfamily
    0.00085   19.3   0.0      0.002   18.1   0.0    1.6  1  NACHT        NACHT domain
      0.007   16.8   0.0        1.6    9.2   0.0    2.9  3  Sigma_M_inh  Sigma-M inhibitor
  ------ inclusion threshold ------
      0.032   14.5   0.0      0.077   13.3   0.0    1.6  1  AAA_22       AAA domain
       0.27   11.0   3.5       0.21   11.3   0.8    2.0  2  DUF1351      Protein of unknown function (DUF1351)


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.1   0.0   1.7e-11   3.1e-08      12      81 ..     869     948 ..     860     950 .. 0.80
   2 !   43.5   0.2   1.9e-14   3.5e-11       1      77 [.     890     978 ..     890     985 .. 0.75
   3 !   22.2   0.1   8.9e-08   0.00016      23      81 ..     949    1022 ..     944    1024 .. 0.70
   4 !   44.4   0.1   1.1e-14   1.9e-11       3      83 .]     999    1094 ..     997    1094 .. 0.77
   5 !   56.6   0.0   1.7e-18     3e-15       1      83 []    1031    1128 ..    1031    1128 .. 0.83
   6 !   37.6   0.0   1.4e-12   2.5e-09       1      73 [.    1101    1184 ..    1101    1193 .. 0.83

  Alignments for each domain:
  == domain 1  score: 34.1 bits;  conditional E-value: 1.7e-11
       Ank_2  12 lvklLlegadpnk...ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLl.ekgadinl 81 
                 +v+ +l+g++ ++   +g   Lh+Aa+ g   ++ +Ll+       ++n+g+tpL +Aar g+  +vklLl e+++d+++
  EEA22225.1 869 TVERFLYGTEYGQrlpKGTIGLHLAAHFGLSRVALTLLKRdsclnvQNNYGWTPLWIAARAGQDAVVKLLLaENNIDCDT 948
                 677777787777335699999********8899999998556766777***********************788999876 PP

  == domain 2  score: 43.5 bits;  conditional E-value: 1.9e-14
       Ank_2   1 LhlAakngnlelvklLl...egadpn..k.ngktaLhyAakngnleivklLleh....ad....ndgrtpLhyAarsghleivklLlekga 77 
                 LhlAa +g + +   Ll   +   +n  +  g+t+L++Aa++g+  +vklLl++     d     ++++pL +Aa +gh  +v+l+lekg+
  EEA22225.1 890 LHLAAHFGLSRVALTLLkrdS--CLNvqNnYGWTPLWIAARAGQDAVVKLLLAEnnidCDtgdaASNHSPLRMAAANGHASVVELFLEKGI 978
                 89****994556666664331..12343259************98889****965755225557779****88888***********9974 PP

  == domain 3  score: 22.2 bits;  conditional E-value: 8.9e-08
       Ank_2   23 nk..ngktaLhyAakngnleivklLleh........ad....ndgrt.pLhyAarsghleivklLl.ekgadinl 81  
                  ++   ++++L  Aa ng+  +v+l+le+         +     +  t +L  A+ +gh ++vklLl +k ++++l
  EEA22225.1  949 GDaaSNHSPLRMAAANGHASVVELFLEKgianpkstGNrmweTTV-TgALTGAVINGHVDVVKLLLtKKCIQVDL 1022
                  4234679*******************9777555554114442223.249*****************433456555 PP

  == domain 4  score: 44.4 bits;  conditional E-value: 1.1e-14
       Ank_2    3 lAakngnlelvklLl.eg...adpnk.ngktaLhyAakngnleivklLleh....ad.....ndgrtpLhyAarsghleivklLlek.gadinlkd 83  
                   A+ ng+ ++vklLl ++   +d+++   +  L++Aa+ng++ +v+lLl      ++      + +tpL +Aa++gh+++v+lL+ +   ++nlkd
  EEA22225.1  999 GAVINGHVDVVKLLLtKKciqVDLKNeRIQGSLWLAARNGHTAVVELLLGLdgvvLNvqskyFYRQTPLSVAASKGHIDVVDLLITSgRTNLNLKD 1094
                  799************8443344444244467******************73456733334555599*******************76467888886 PP

  == domain 5  score: 56.6 bits;  conditional E-value: 1.7e-18
       Ank_2    1 LhlAakngnlelvklLl..egadpn..k...ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLl.ekgadinlk 82  
                  L lAa+ng++ +v+lLl   g+ +n  +     +t+L +Aa++g++++v lL+          d++grtpL++A+r+gh+ +vklLl  +g+d +++
  EEA22225.1 1031 LWLAARNGHTAVVELLLglDGVVLNvqSkyfYRQTPLSVAASKGHIDVVDLLITSgrtnlnlKDDKGRTPLFLASRNGHESVVKLLLtLNGIDRDAT 1127
                  679*****99*******7666556664257999********************8556565544599*********************5569987766 PP

       Ank_2   83 d 83  
                  d
  EEA22225.1 1128 D 1128
                  5 PP

  == domain 6  score: 37.6 bits;  conditional E-value: 1.4e-12
       Ank_2    1 LhlAakngnlelvklLl..egadpn..k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLl 73  
                  L+lA++ng+ ++vklLl  +g d +  +   +t+L +Aa +g+  +v+ Ll         dn+g+tp  +A+  g+ +++ lL 
  EEA22225.1 1101 LFLASRNGHESVVKLLLtlNGIDRDatDiSARTPLSAAAARGHFTVVQSLLGSganptlKDNYGWTPFLWASAIGQRNVMHLLQ 1184
                  7899****99*******99998877653789********************7554566666*******9999779989998885 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   0.2   3.4e-08   6.1e-05       5      55 .]     890     939 ..     887     939 .. 0.94
   2 !   12.0   0.1   0.00013      0.24      11      55 .]     929     974 ..     927     974 .. 0.85
   3 !   20.1   0.0   4.1e-07   0.00073       5      55 .]     997    1047 ..     993    1047 .. 0.90
   4 !   34.0   0.0   1.8e-11   3.2e-08       3      55 .]    1065    1117 ..    1063    1117 .. 0.95
   5 !   29.6   0.0   4.1e-10   7.3e-07       2      54 ..    1132    1183 ..    1131    1184 .. 0.94

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 3.4e-08
       Ank_4   5 LhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 Lh aa++g  +++  Ll ++  +n q n++G+t+l+iAa+ g+  ++klLl
  EEA22225.1 890 LHLAAHFGLSRVALTLLKRDSCLNVQ-NNYGWTPLWIAARAGQDAVVKLLL 939
                 899999999999999**99*******.****************99999997 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 0.00013
       Ank_4  11 sgrlelvrlLl.ekgadinaqdnrsGe.talhiAakrgnveilklLl 55 
                 +g+  +v+lLl e+++d++   ++  + ++l +Aa +g+ ++++l+l
  EEA22225.1 929 AGQDAVVKLLLaENNIDCDTG-DAASNhSPLRMAAANGHASVVELFL 974
                 6777899*999789***9998.7666647****************97 PP

  == domain 3  score: 20.1 bits;  conditional E-value: 4.1e-07
       Ank_4    5 LhyaaisgrlelvrlLlekg.adinaqdnrsGetalhiAakrgnveilklLl 55  
                  L  a+i g++++v+lLl k+ ++++   n++ +  l+ Aa++g+  +++lLl
  EEA22225.1  997 LTGAVINGHVDVVKLLLTKKcIQVDLK-NERIQGSLWLAARNGHTAVVELLL 1047
                  5568999**********776799***8.***********************8 PP

  == domain 4  score: 34.0 bits;  conditional E-value: 1.8e-11
       Ank_4    3 taLhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAakrgnveilklLl 55  
                  t+L  aa++g++++v+lL+ + + ++n   ++ G+t+l  A ++g+ +++klLl
  EEA22225.1 1065 TPLSVAASKGHIDVVDLLITSgRTNLNLK-DDKGRTPLFLASRNGHESVVKLLL 1117
                  7999***************8867*****9.999********************8 PP

  == domain 5  score: 29.6 bits;  conditional E-value: 4.1e-10
       Ank_4    2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54  
                  +t+L +aa+ g++ +v++Ll +ga++    +++G+t++  A  +g+ ++ +lL
  EEA22225.1 1132 RTPLSAAAARGHFTVVQSLLGSGANPTLK-DNYGWTPFLWASAIGQRNVMHLL 1183
                  89**************************8.9**************99888877 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.1   0.6    0.0046       8.2       6      32 .]     890     917 ..     890     917 .. 0.89
   2 !   15.2   0.0   1.2e-05     0.022       1      27 [.     918     944 ..     918     949 .. 0.83
   3 !   10.8   0.0    0.0003      0.54       4      28 ..     956     982 ..     954     986 .. 0.84
   4 ?    3.2   0.1     0.079   1.4e+02      10      23 ..    1001    1015 ..     996    1024 .. 0.76
   5 !    8.8   0.1    0.0013       2.4       6      29 ..    1031    1056 ..    1031    1059 .. 0.80
   6 !   17.6   0.0   2.1e-06    0.0037       3      32 .]    1064    1095 ..    1062    1095 .. 0.93
   7 !   22.6   0.0   5.6e-08    0.0001       2      31 ..    1097    1128 ..    1096    1129 .. 0.93
   8 !   15.1   0.0   1.3e-05     0.024       3      32 .]    1132    1162 ..    1132    1162 .. 0.94
   9 ?   -0.1   0.0      0.87   1.6e+03       1      21 [.    1163    1183 ..    1163    1189 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0046
                 HHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank   6 LHlAatngkkriiklLL.hGAnlnaldn 32 
                 LHlAa++g  r++  LL + ++ln ++n
  EEA22225.1 890 LHLAAHFGLSRVALTLLkRDSCLNVQNN 917
                 9************999*64579****97 PP

  == domain 2  score: 15.2 bits;  conditional E-value: 1.2e-05
                 TSBBHHHHHHHHTTHHHHHHHH.TTTST CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hGAnl 27 
                 +G+TPL +Aa+ g+  ++klLL    n+
  EEA22225.1 918 YGWTPLWIAARAGQDAVVKLLLaEN-NI 944
                 6*********************433.44 PP

  == domain 3  score: 10.8 bits;  conditional E-value: 0.0003
                 BHHHHHHHHTTHHHHHHHH.TT.TSTT CS
         Ank   4 TPLHlAatngkkriiklLL.hG.Anln 28 
                 +PL +Aa ng++++++l+L +G An+ 
  EEA22225.1 956 SPLRMAAANGHASVVELFLeKGiANPK 982
                 67777787***********99***985 PP

  == domain 4  score: 3.2 bits;  conditional E-value: 0.079
                  HHHTTHHHHHHHH.T CS
         Ank   10 atngkkriiklLL.h 23  
                  + ng+++++klLL +
  EEA22225.1 1001 VINGHVDVVKLLLtK 1015
                  5589********943 PP

  == domain 5  score: 8.8 bits;  conditional E-value: 0.0013
                  HHHHHHHTTHHHHHHHH..TTTSTTC CS
         Ank    6 LHlAatngkkriiklLL..hGAnlna 29  
                  L lAa+ng++ +++lLL  +G  ln 
  EEA22225.1 1031 LWLAARNGHTAVVELLLglDGVVLNV 1056
                  789*************9666743565 PP

  == domain 6  score: 17.6 bits;  conditional E-value: 2.1e-06
                  BBHHHHHHHHTTHHHHHHHH.TT.TSTTCBTT CS
         Ank    3 nTPLHlAatngkkriiklLL.hG.Anlnaldn 32  
                   TPL +Aa+ g+ +++ lL+ +G  nln++d+
  EEA22225.1 1064 QTPLSVAASKGHIDVVDLLItSGrTNLNLKDD 1095
                  6*******************9888*****996 PP

  == domain 7  score: 22.6 bits;  conditional E-value: 5.6e-08
                  SBBHHHHHHHHTTHHHHHHHH..TTTSTTCBT CS
         Ank    2 GnTPLHlAatngkkriiklLL..hGAnlnald 31  
                  G+TPL lA++ng+++++klLL  +G + +a+d
  EEA22225.1 1097 GRTPLFLASRNGHESVVKLLLtlNGIDRDATD 1128
                  9*******************9888*9999998 PP

  == domain 8  score: 15.1 bits;  conditional E-value: 1.3e-05
                  BBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank    3 nTPLHlAatngkkriiklLL.hGAnlnaldn 32  
                  +TPL  Aa +g+  +++ LL +GAn++++dn
  EEA22225.1 1132 RTPLSAAAARGHFTVVQSLLgSGANPTLKDN 1162
                  5****99989**********999******98 PP

  == domain 9  score: -0.1 bits;  conditional E-value: 0.87
                  TSBBHHHHHHHHTTHHHHHHH CS
         Ank    1 dGnTPLHlAatngkkriiklL 21  
                  +G+TP  +A+ +g+ ++ +lL
  EEA22225.1 1163 YGWTPFLWASAIGQRNVMHLL 1183
                  69*******988877798866 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.1       1.7   3.1e+03       6      23 ..     890     907 ..     890     910 .. 0.86
   2 !   20.3   0.0   2.9e-07   0.00052       1      30 [.     918     947 ..     918     948 .. 0.95
   3 !    9.0   0.0    0.0014       2.5       3      27 ..     955     978 ..     953     982 .. 0.86
   4 ?    3.2   0.0      0.11   1.9e+02       9      26 ..    1000    1017 ..    1000    1022 .. 0.83
   5 !    7.0   0.0     0.006        11       6      24 ..    1031    1049 ..    1028    1056 .. 0.84
   6 !   13.2   0.0   5.7e-05       0.1       2      29 ..    1063    1090 ..    1062    1092 .. 0.85
   7 !   18.2   0.0   1.4e-06    0.0024       2      30 ..    1097    1125 ..    1096    1126 .. 0.92
   8 !    9.3   0.0    0.0011         2       3      29 ..    1132    1157 ..    1131    1159 .. 0.93
   9 ?    3.4   0.0     0.087   1.6e+02       1      21 [.    1163    1183 ..    1163    1187 .. 0.89

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 1.7
       Ank_3   6 LhlAarsgnleivkfLle 23 
                 LhlAa++g   ++  Ll+
  EEA22225.1 890 LHLAAHFGLSRVALTLLK 907
                 9*******9998888887 PP

  == domain 2  score: 20.3 bits;  conditional E-value: 2.9e-07
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvn 30 
                 +G+tpL +Aar+g  ++vk+Ll ++++d++
  EEA22225.1 918 YGWTPLWIAARAGQDAVVKLLLAENNIDCD 947
                 7**********************99**987 PP

  == domain 3  score: 9.0 bits;  conditional E-value: 0.0014
       Ank_3   3 etpLhlAarsgnleivkfLlenkga 27 
                  +pL +Aa +g+ ++v+++le kg+
  EEA22225.1 955 HSPLRMAAANGHASVVELFLE-KGI 978
                 69*******************.565 PP

  == domain 4  score: 3.2 bits;  conditional E-value: 0.11
       Ank_3    9 AarsgnleivkfLlenkg 26  
                  A+ +g++++vk+Ll +k 
  EEA22225.1 1000 AVINGHVDVVKLLLTKKC 1017
                  899***********9655 PP

  == domain 5  score: 7.0 bits;  conditional E-value: 0.006
       Ank_3    6 LhlAarsgnleivkfLlen 24  
                  L lAar+g++++v++Ll  
  EEA22225.1 1031 LWLAARNGHTAVVELLLGL 1049
                  889*************975 PP

  == domain 6  score: 13.2 bits;  conditional E-value: 5.7e-05
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadv 29  
                   +tpL +Aa+ g++++v++L+     ++
  EEA22225.1 1063 RQTPLSVAASKGHIDVVDLLITSGRTNL 1090
                  58*******************9666655 PP

  == domain 7  score: 18.2 bits;  conditional E-value: 1.4e-06
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                  G+tpL+lA r+g+ ++vk+Ll  +g+d +
  EEA22225.1 1097 GRTPLFLASRNGHESVVKLLLTLNGIDRD 1125
                  9*********************9999965 PP

  == domain 8  score: 9.3 bits;  conditional E-value: 0.0011
       Ank_3    3 etpLhlAarsgnleivkfLlenkgadv 29  
                  +tpL  Aa  g++++v+ Ll   ga++
  EEA22225.1 1132 RTPLSAAAARGHFTVVQSLLG-SGANP 1157
                  7*******************9.89987 PP

  == domain 9  score: 3.4 bits;  conditional E-value: 0.087
       Ank_3    1 nGetpLhlAarsgnleivkfL 21  
                  +G+tp+ +A   g  +++++L
  EEA22225.1 1163 YGWTPFLWASAIGQRNVMHLL 1183
                  7*************9988887 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.1   2.6e-07   0.00047      19      55 ..     889     925 ..     884     926 .. 0.92
   2 !   16.9   0.2   3.3e-06    0.0059      10      56 .]     913     961 ..     912     961 .. 0.92
   3 !   12.8   0.2   6.4e-05      0.12       2      40 ..     939     978 ..     937     991 .. 0.85
   4 ?    1.9   0.0      0.17     3e+02      23      39 ..    1000    1017 ..    1000    1032 .. 0.77
   5 ?    4.0   0.0     0.037        67      22      39 ..    1033    1051 ..    1019    1060 .. 0.81
   6 !   23.4   0.0   2.9e-08   5.3e-05       7      53 ..    1054    1101 ..    1049    1101 .. 0.92
   7 !   20.3   0.0   2.7e-07   0.00049       8      53 ..    1089    1135 ..    1086    1136 .. 0.97
   8 !   22.4   0.0   6.4e-08   0.00011      18      53 ..    1133    1168 ..    1128    1169 .. 0.95

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 2.6e-07
       Ank_5  19 pLhvAakygaadvvrlLlargadlnltdsrGltaldl 55 
                  Lh+Aa+ g ++v++ Ll+r + ln+++++G+t+l +
  EEA22225.1 889 GLHLAAHFGLSRVALTLLKRDSCLNVQNNYGWTPLWI 925
                 6*********************************965 PP

  == domain 2  score: 16.9 bits;  conditional E-value: 3.3e-06
       Ank_5  10 nrldgggntpLhvAakygaadvvrlLl.argadlnltdsrG.ltaldlA 56 
                 n ++++g tpL +Aa++g   vv+lLl +++ d+++ d+    ++l +A
  EEA22225.1 913 NVQNNYGWTPLWIAARAGQDAVVKLLLaENNIDCDTGDAASnHSPLRMA 961
                 88999999****************************9999888888876 PP

  == domain 3  score: 12.8 bits;  conditional E-value: 6.4e-05
       Ank_5   2 lehgpadvnrldgggn.tpLhvAakygaadvvrlLlarga 40 
                 l++ ++d+++ d  +n +pL +Aa +g+a+vv+l+l+ g 
  EEA22225.1 939 LAENNIDCDTGDAASNhSPLRMAAANGHASVVELFLEKGI 978
                 55557*******************************6654 PP

  == domain 4  score: 1.9 bits;  conditional E-value: 0.17
       Ank_5   23 AakygaadvvrlLl.arg 39  
                  A+ +g+ dvv+lLl +  
  EEA22225.1 1000 AVINGHVDVVKLLLtKKC 1017
                  889***********6655 PP

  == domain 5  score: 4.0 bits;  conditional E-value: 0.037
       Ank_5   22 vAakygaadvvrlLl.arg 39  
                  +Aa++g+  vv+lLl   g
  EEA22225.1 1033 LAARNGHTAVVELLLgLDG 1051
                  7**************4444 PP

  == domain 6  score: 23.4 bits;  conditional E-value: 2.9e-08
       Ank_5    7 advnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltal 53  
                   +v+ +  +++tpL vAa++g+ dvv lL+   + +lnl+d+ G+t+l
  EEA22225.1 1054 LNVQSKYFYRQTPLSVAASKGHIDVVDLLItSGRTNLNLKDDKGRTPL 1101
                  57778888999************************************8 PP

  == domain 7  score: 20.3 bits;  conditional E-value: 2.7e-07
       Ank_5    8 dvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltal 53  
                  ++n +d +g tpL +A+++g+ +vv+lLl  +g d+++td + +t+l
  EEA22225.1 1089 NLNLKDDKGRTPLFLASRNGHESVVKLLLtLNGIDRDATDISARTPL 1135
                  789******************************************98 PP

  == domain 8  score: 22.4 bits;  conditional E-value: 6.4e-08
       Ank_5   18 tpLhvAakygaadvvrlLlargadlnltdsrGltal 53  
                  tpL  Aa +g+++vv+ Ll  ga+++l+d++G+t++
  EEA22225.1 1133 TPLSAAAARGHFTVVQSLLGSGANPTLKDNYGWTPF 1168
                  9*********************************96 PP

>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.0   1.3e-08   2.3e-05       3     119 ..      14     139 ..      12     172 .. 0.69
   2 !   15.9   0.0   3.2e-06    0.0057     139     233 ..     265     348 ..     246     349 .. 0.87
   3 ?    2.0   0.1     0.058     1e+02      30      96 ..    1256    1328 ..    1233    1359 .. 0.79

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 1.3e-08
                 EEEESSH.HHHHHHHHH..EEEEEEEEEE.TTEEEEEEEETTEEEEEEE--...SSHHHHHHHHHHHHHHHC.--SEEEEEEEEEESSTTT-TT-EEEE CS
   PNP_UDP_1   3 aiivgsp.gevellaes..pleetpfgregrgfkfvtGtlkgkpvvivstG...iGkpnaavvaeirllkef.gvkaiiriGtaGglnpdlkvGDvvip 94 
                 + +++ p +  ++la    + +++p + +     +++G++++++vvi++     iG   aa   +++++ +f ++k  +++G+ Gg+ p++++GDvv++
  EEA22225.1  14 GWVCALPkEQTAALAMLdeKHADLPKQQN-DPNVYTLGSVGKHNVVIACLPmgmIGNNKAA-NVAAHMVSSFpSIKFGLMVGIGGGVPPNVRLGDVVVS 110
                 56788886333333333333666666666.8889**************9995655666666.55566666885566669******************** PP

                 EEEEESSSCCGCCTHHCC....TCCCCTT CS
   PNP_UDP_1  95 ddainfdgrsplygpkee....gqyfpds 119
                 + +  ++g  +  + k e    +q+  + 
  EEA22225.1 111 KPVSEYSGVVQWDFGKAEqrgtFQRTGAL 139
                 *9877777777555555545443444444 PP

  == domain 2  score: 15.9 bits;  conditional E-value: 3.2e-06
                 TTTTEEEEEEEEESESS-CHHHHHHHHHHTC..-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTBETTCTCH.HCCCHHHHHHHHHHHHHHHHHH CS
   PNP_UDP_1 139 lgikvhrGvvatadgfyaeteaelrllrrlg..adaveMEtaavaqlArelgipfaairvvsdlaaggadaeatheeveefaqeaaknaaalllall 233
                 +++++h+G++a+++++  +  +++ + ++lg  + + eME+a + +     + p+++ir++ d+a+           +++ +++aa  aaa+++++l
  EEA22225.1 265 RNMRLHYGLIASGNQVIKDAIRRDGINKMLGgnVLCFEMEAAGLMH-----DFPCLVIRGICDYADS--------HKNKKWQEHAAAVAAAFAKEFL 348
                 4599****************888889999999999******98865.....9***********7777........7888899999999999999987 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.058
                  TTEEEEEEEETTEEEEEEE--.SSHHHHH.HHHHHHHHHHC.--SEEEEEEEEEES...STTT-TT-EEEEEE CS
   PNP_UDP_1   30 rgfkfvtGtlkgkpvvivstG.iGkpnaa.vvaeirllkef.gvkaiiriGtaGgl...npdlkvGDvvipdd 96  
                   ++ +++G +  +++v+++      + a+ ++   r+l  f +v+a + +G++ g+    pd+++GDvv+   
  EEA22225.1 1256 DEYVYFLGCISSHNIVVACPEfPPRDDASlMTIGSRILRTFtSVRAALLVGISEGVptkEPDIHLGDVVVGAG 1328
                  566777777888888888888445566666666778888888999999999999999999*********9866 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   1.1e-06     0.002       5     128 ..     449     590 ..     445     620 .. 0.67

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 1.1e-06
                 EEC-TTTCHHHHHHHHHHHHCTS-SCCCC.-SEEEEEETTTTTTS-......-HCHHHCCCCTS--SSS-C...................CHHHHCCSC CS
       NACHT   5 lqGeaGsGKTtLlqklalawaegklpqga.fklvFflslrelsrsgna...rsladllfsqlpepaapvse...................vwavllelp 80 
                   G +G GKT+    +++ ++++  +        ++ ++r+ +++++    +sl +++ + +p   + v++                   v+  +++ +
  EEA22225.1 449 CPGIPGAGKTIATSIVVHHLQRKFRNDTSvGIAYLYCNFRQHQKQNPKdliLSLLKQIIRGMPSVPKYVEQlylehsrkgtrptfeeitdVFFSVVAGF 547
                 56899*****97777777776666555444445566667777776655667788888888888888888779999999999995555555555555555 PP

                 CCEEEEEE-STT-SS-TCH.........HHHHHCTTTTT--EEEEEEE CS
       NACHT  81 erlLlilDglDelvtdlgqkekqpvrtlLselirkkllpeasllltvr 128
                   + +i+D+lDe+   +g+  + +    + +l  +   ++a +++t+r
  EEA22225.1 548 SWTFIIIDALDECNISDGA--RSKFMSTIFDLHDR---TRANVFATSR 590
                 5555**********99999..44444444444444...5555555554 PP

>> Sigma_M_inh  Sigma-M inhibitor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       7.2   1.3e+04      47      78 ..     509     541 ..     499     556 .. 0.60
   2 ?    4.0   0.0     0.039        70      20      67 ..     932     981 ..     912     989 .. 0.77
   3 !    9.2   0.0   0.00088       1.6      20      69 ..    1040    1092 ..    1026    1094 .. 0.80

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 7.2
  Sigma_M_inh  47 amaavplgvvelfikkgrtglg.llgvvlnlfv 78 
                   m +vp  v +l++ + r g    +  + ++f 
   EEA22225.1 509 GMPSVPKYVEQLYLEHSRKGTRpTFEEITDVFF 541
                  588899999999999999875313334444443 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.039
  Sigma_M_inh  20 tavlsllllnlailsdviaysykmlpfamaav..plgvvelfikkgrtgl 67 
                   av+ lll +  i  d+   + +  p+ maa      vvelf+ kg + +
   EEA22225.1 932 DAVVKLLLAENNIDCDTGDAASNHSPLRMAAAngHASVVELFLEKGIANP 981
                  5899999999999999988888888888887622579********97765 PP

  == domain 3  score: 9.2 bits;  conditional E-value: 0.00088
  Sigma_M_inh   20 tavlslll.lnlailsdviaysykmlpfamaav..plgvvelfikkgrtglgl 69  
                   tav+ lll l+  +l     y y+  p+++aa    + vv+l+i  grt l l
   EEA22225.1 1040 TAVVELLLgLDGVVLNVQSKYFYRQTPLSVAASkgHIDVVDLLITSGRTNLNL 1092
                   78888877466666777789********9999733589***********9865 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   4.3e-05     0.077       4     117 ..     443     579 ..     440     589 .. 0.66

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 4.3e-05
      AAA_22   4 tagilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsst....sskdllrellralglelka............erlsseellealeqal 86 
                  ++il++ G +G+GKT     +++ l+ +++ ++ ++++++ +++       ++kdl   ll+++ ++  +            +r+ ++  +e +++ +
  EEA22225.1 443 PKQILFCPGIPGAGKTIATSIVVHHLQ-RKFRNDTSVGIAYLYCNFRQhqkqNPKDLILSLLKQIIRGMPSvpkyveqlylehSRKGTRPTFEEITDVF 540
                 689*********************995.55555556666655555444448899999999999888777766677766666665555555555555555 PP

      AAA_22  87 rarav...ielliiDEaqhlr.s....eealeeLrslln 117
                  +  +     ++iiD  +  + s     + ++++ +l++
  EEA22225.1 541 FSVVAgfsWTFIIIDALDECNiSdgarSKFMSTIFDLHD 579
                 555546666677777666655522333555555555555 PP

>> DUF1351  Protein of unknown function (DUF1351)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.8   0.00012      0.21      98     187 ..     322     413 ..     315     420 .. 0.80
   2 ?   -1.1   0.1      0.75   1.3e+03     160     203 ..     634     677 ..     600     680 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00012
     DUF1351  98 efeekekeekkkevkalise.laeeae..veleeieiqekwlnktvslkkieeeieaakaekikkdreelekakaeieekakafeleasaylr 187
                  + +  k++k +e  a+++  +a+e    v+++e+++ +++      ++ki  ++ ++k ++i +++++ +++++++++++ +  l++ +y +
  EEA22225.1 322 DYADSHKNKKWQEHAAAVAAaFAKEFLsmVPAQEVDMMPTIKSLHEGIEKISRNVDDIKQRQIIQEENSEQQQRSQVHQAILD-WLTSTDYSS 413
                 56677788887776666655045554467*************************************99************999.667766655 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.75
     DUF1351 160 dreelekakaeieekakafeleasaylrllkegkslsdvlkqid 203
                 d e  ek ka+i ++a+ + l a+  l+ l++  +l++v +  +
  EEA22225.1 634 DPELEEKVKATIVKAADGMFLLAKLHLDSLEDKINLTQVEQALE 677
                 44445778999999999999999999999999999999977665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1535 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       749  (0.0417759); expected 358.6 (0.02)
Passed bias filter:                      633  (0.0353059); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 1.08u 0.33s 00:00:01.41 Elapsed: 00:00:00.52
# Mc/sec: 8960.24
//
Query:       EEA22226.1  [L=308]
Description: YjeF domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.7e-44  152.1   0.2    1.5e-43  149.0   0.2    1.9  1  Carb_kinase  Carbohydrate kinase


Domain annotation for each model (and alignments):
>> Carb_kinase  Carbohydrate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  149.0   0.2   8.4e-48   1.5e-43      20     206 ..       2     243 ..       1     295 [. 0.81

  Alignments for each domain:
  == domain 1  score: 149.0 bits;  conditional E-value: 8.4e-48
                  HHHCTT-SEEEEEESSTTTCCCCTTTTTCEECCTT.............HTTTS....--SSS-SEEEE-TT-SSSHCHHH....HCHHHCCCCS-EEE CS
  Carb_kinase  20 aalrlgaglvsvateseaiavlksylpevivhpll.............edeqa.kileklerldavviGpGLgrdekikk....lleevlekdeplvi 99 
                  a +rlg++l +v++e+ a+ v+k+y+p+++vhp+l              ++ a  il+ l rl+++viGpGLgrd  ++k    +++e+++k +p+v+
   EEA22226.1   2 ASARLGCDLSHVICERSAAPVIKAYSPNLMVHPILpstasvsespsedPASLAsPILDMLPRLHVLVIGPGLGRDGVTQKvvieIMKEARNKSVPFVL 99 
                  7899****************************************998744556689*********************9999999999*********** PP

                  EGGGGGSGGGG...TTTTSSEEEE--HHHHHHHCTTTCH............HCCSHHHHHHHHHHHHTT.EEEEESTTSEEEECTTEEEEE----GGG CS
  Carb_kinase 100 DAdgLnllaqknelserkaeviLTPhkkEfkrLlkaivk............keddrlelarelaqklna.vvllkgekdvivspegevlinstgssal 184
                  DAdgL+l+ +k +l +  +e iLTP+++Ef rL+ka++             + ++ +e++++l+q+l++ +++ kg+kdvi + +   +i +  ++++
   EEA22226.1 100 DADGLMLVIEKPDLVKGYKECILTPNVVEFGRLAKALGVqvsttkdqddekELSKASEACEKLSQALGGvTIIQKGAKDVISN-GVTSIISDLRGGLK 196
                  *************************************9999****999998888999*********98626888888888877.6666666788999* PP

                  -STTHHHHHHHHHHHHHHCTS.........................S CS
  Carb_kinase 185 akGGsGDvLaGligalLaqne.........................a 206
                  ++GG+GD+L+G++g l+a+ +                         a
   EEA22226.1 197 RSGGQGDTLTGSLGTLMAWRAayhnglwdtgeksskstaqskdevqA 243
                  *******************9955555555544444444444444440 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (308 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       632  (0.0352502); expected 358.6 (0.02)
Passed bias filter:                      536  (0.0298957); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.29s 00:00:00.79 Elapsed: 00:00:00.47
# Mc/sec: 1981.49
//
Query:       EEA22227.1  [L=318]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-08   34.8  16.3    1.9e-08   34.8  16.3    2.0  2  SPT2      SPT2 chromatin protein


Domain annotation for each model (and alignments):
>> SPT2  SPT2 chromatin protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.3      0.45     8e+03      65      73 ..     153     161 ..     143     169 .. 0.57
   2 !   34.8  16.3     1e-12   1.9e-08      55     110 ..     253     307 ..     239     308 .. 0.86

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.45
        SPT2  65 dddrdMEan 73 
                 + +r MEa+
  EEA22227.1 153 EMKRRMEAK 161
                 233445554 PP

  == domain 2  score: 34.8 bits;  conditional E-value: 1e-12
        SPT2  55 yesrddaesddddrdMEangaeieeEErrSariArkEDeeEeerekreeeekkkrk 110
                 y+ +dd+ sd  ++dMEa++ ++e+EE  + r A++EDee+ ++e++ +++k +rk
  EEA22227.1 253 YDDYDDYYSDA-SSDMEAGYGDMEREEYAALRAAQREDEEDIRMEAEAKRAKMERK 307
                 33346666666.69*****************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (318 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1186  (0.0661498); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.32s 00:00:00.88 Elapsed: 00:00:00.51
# Mc/sec: 1893.94
//
Query:       EEA22228.1  [L=111]
Description: 60S acidic ribosomal protein P2/allergen Asp F 8 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.7e-27   95.8  12.5      2e-27   95.6  12.5    1.0  1  Ribosomal_60s  60s Acidic ribosomal protein
  ------ inclusion threshold ------
       0.14   12.5   0.0       0.23   11.8   0.0    1.4  1  EF-hand_14     EF-hand domain
       0.15   10.5   1.7       0.17   10.3   1.7    1.1  1  Cytomega_UL84  Cytomegalovirus UL84 protein
        2.4    8.8   5.4        3.3    8.4   5.4    1.2  1  DUF3824        Domain of unknwon function (DUF3824)


Domain annotation for each model (and alignments):
>> Ribosomal_60s  60s Acidic ribosomal protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.6  12.5   4.4e-31     2e-27       1      88 []      17     110 ..      17     110 .. 0.95

  Alignments for each domain:
  == domain 1  score: 95.6 bits;  conditional E-value: 4.4e-31
                    XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.....XXXXXXXXXXXXXXXXXXXXXXXXXXXX..XX--SS--STTT CS
  Ribosomal_60s   1 eptaenikkvlkaagveveaarvkllvkalegkdieellangaakla.....aaaaaaaaaaaaaaaaaaaeekkkeeeee.EeedddmGfgLF 88 
                    +p+a++i++vl+++g++++++r++ l+++legkdi el+a+g++kla     +a++a+aa++aaa++aaaaeek++e+eee Ee+d+dmGfgLF
     EEA22228.1  17 SPSAKDITAVLESVGIDADEERLEKLISELEGKDISELIAEGSTKLAsvpsgGAGGAPAAGGAAAGGAAAAEEKAEEKEEEkEESDEDMGFGLF 110
                    59**************************************************889999999999999999999999999888************ PP

>> EF-hand_14  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   5.1e-05      0.23      18      49 ..      19      50 ..       7      63 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 5.1e-05
  EF-hand_14 18 svakllkaLaetGirkdDpRLkellkklkkve 49
                s ++++++L+++Gi  d  RL++l+++l+  +
  EEA22228.1 19 SAKDITAVLESVGIDADEERLEKLISELEGKD 50
                6678999********************98665 PP

>> Cytomega_UL84  Cytomegalovirus UL84 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   1.7   3.7e-05      0.17     139     176 ..      67     104 ..      43     107 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 3.7e-05
  Cytomega_UL84 139 ngesqtapatsqeeetaashepekkkekeekkeeeded 176
                     g +  apa+       a+   ek  ekee kee ded
     EEA22228.1  67 SGGAGGAPAAGGAAAGGAAAAEEKAEEKEEEKEESDED 104
                    4667789999999888899999***************9 PP

>> DUF3824  Domain of unknwon function (DUF3824)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   5.4   0.00074       3.3      10      38 ..      75     102 ..      69     106 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00074
     DUF3824  10 AeaalaaggaglAaheyakrrerkkaere 38 
                 A+ ++aagga+ A ++++++ e+k+++ +
  EEA22228.1  75 AAGGAAAGGAAAAEEKAEEKEEEKEES-D 102
                 667777888887777777777777643.3 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (111 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       939  (0.0523733); expected 358.6 (0.02)
Passed bias filter:                      533  (0.0297284); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.41
# Mc/sec: 807.53
//
Query:       EEA22229.1  [L=153]
Description: 40S ribosomal protein S15, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.7e-34  115.4   0.3    1.1e-33  114.9   0.3    1.2  1  Ribosomal_S19  Ribosomal protein S19


Domain annotation for each model (and alignments):
>> Ribosomal_S19  Ribosomal protein S19
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.9   0.3   6.3e-38   1.1e-33       1      81 []      51     136 ..      51     136 .. 0.94

  Alignments for each domain:
  == domain 1  score: 114.9 bits;  conditional E-value: 6.3e-38
                    .HHHSS.TTCCCHHHHHHHHHH..TS-...----EEES-TT-B--GGGTT-EEEEE-SSSEEEEE--CCCTTSBCGGGT-SS----S CS
  Ribosomal_S19   1 rslkkg.pfvqesllkkvrkak..aek...kkevikthsRdstIlPemvgltvgVynGktfvpveikeemvGhkLgEFspTrkpvkh 81 
                    r++++g +++   l+kk+rkak  a k   k++ +kth+Rd++++Pem+g+++g+y Gk+f++veik+emvGh+LgEFs+++kpvkh
     EEA22229.1  51 RRFNRGlKRKPMGLIKKLRKAKqeA-KpneKPDLVKTHLRDMIVVPEMIGSVIGIYSGKEFNQVEIKPEMVGHYLGEFSISYKPVKH 136
                    67899*99************99642.257899******************************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (153 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       678  (0.0378158); expected 358.6 (0.02)
Passed bias filter:                      501  (0.0279436); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.29s 00:00:00.69 Elapsed: 00:00:00.43
# Mc/sec: 1077.97
//
Query:       EEA22230.1  [L=527]
Description: SET and MYND domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.1e-15   55.8   1.7    8.5e-15   55.5   0.0    2.0  2  SET       SET domain
      2e-07   31.0  12.5      2e-07   31.0  12.5    2.5  3  zf-MYND   MYND finger


Domain annotation for each model (and alignments):
>> SET  SET domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.5   0.0   9.5e-19   8.5e-15       1     168 [.      27     259 ..      27     260 .. 0.65
   2 ?   -1.5   0.4      0.32   2.9e+03      48      71 ..     464     491 ..     293     512 .. 0.62

  Alignments for each domain:
  == domain 1  score: 55.5 bits;  conditional E-value: 9.5e-19
                 SCEEEESSXBXTTXEEEEEE.......ECCEECHHHHHHHHHH........................................................ CS
                 xxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxxxx........................................................ RF
         SET   1 GrGvfAtedIpkgeficeyp.......eeiiltkdeadksele........................................................ 36 
                 G GvfAt +I+kg+ ++ ++       ee+ l + +      +                                                        
  EEA22230.1  27 GLGVFATANIKKGADVLVIDtpmvalvEEKQLKNIC------Sgcfdtskaasidsrrpglvkacvrckvvyycdkncqrkdwkaghsvecaiysklyp 119
                 89**************74444222222334444444......356666699999999999999999999999999999999999999999998888776 PP

                 .......................HTEEEEEXGGXXGGSX.HHHHHHHTTSSHHHHHHHHHHHHHHHHHHTHHHHHHHXTTTSX...XXHCCCCC..HCC CS
                 .......................xxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxx..xxx RF
         SET  37 .......................aylfslpeapknlaft.kelakasastllqklakdqkqaekedtdaalkasskaesdlna...skpeagaf..sai 106
                                        +              + +e   +s +++++++ ++++ + ++  + a+ +  + e   ++      ++  +  s +
  EEA22230.1 120 rilplpvrailrvilsqdkdkvsP-------------YIhEEFLDLSYPKEIYDDDENEEANDHFLMAEAVLKYGDIEYLDEDyveQ-LFGKLSanSFT 204
                 666666664443333333333332.............32356666666666666666666666666555555555444433323421.22222234555 PP

                 CHEEEETEEEEEECCCGTTGGGCEEXSSSSEEEEEEEETTSSEEEEEESSXBXTTEEEEEXT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         SET 107 agysidaralksgngagplarflNHsCdpNcnltvqnvlrgprvavfAtrdIkkGeEltidY 168
                  ++++  r   + ++a   a  +NHsC+pN+  ++++  + ++ +++At++I+kGe+++i Y
  EEA22230.1 205 LTSAFGKRRGVYLHPA---AARFNHSCNPNA--SYSF--DKGKCYIRATKPIAKGEQIFIPY 259
                 5566666666666655...9999********..5555..56*******************99 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.32
                 X....GGSXHHHHHHHTTSSHHHHHHHH CS
                 x....xxxxxxxxxxxxxxxxxxxxxxx RF
         SET  48 n....laftkelakasastllqklakdq 71 
                        +t+  aka+a++ l++l+++ 
  EEA22230.1 464 KkmeeAVWTNPTAKADAERILKWLTEEL 491
                 1222222235555555555555555555 PP

>> zf-MYND  MYND finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.1      0.21   1.9e+03      10      16 ..      58      65 ..      54      73 .. 0.70
   2 !   31.0  12.5   2.3e-11     2e-07       1      38 []      62     111 ..      62     111 .. 0.75
   3 ?   -0.7   0.4      0.17   1.6e+03      12      17 ..     282     287 ..     270     292 .. 0.75

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.21
                SC.E-TTT CS
     zf-MYND 10 lk.kCagC 16
                lk  C+gC
  EEA22230.1 58 LKnICSGC 65
                45589999 PP

  == domain 2  score: 31.0 bits;  conditional E-value: 2.3e-11
                 -TTT--............B-SCE-TTTS-SEESSHHHHHHCH.HHHCCCH CS
     zf-MYND   1 CavCgk...........aealkkCagCksvfYCskeCqradw.ksHkteC 38 
                 C+ C+                k C +Ck v+YC+k+Cqr+dw   H  eC
  EEA22230.1  62 CSGCFDtskaasidsrrPGLVKACVRCKVVYYCDKNCQRKDWkAGHSVEC 111
                 55666666666655542233459*******************778***** PP

  == domain 3  score: -0.7 bits;  conditional E-value: 0.17
                 E-TTTS CS
     zf-MYND  12 kCagCk 17 
                 +C++C 
  EEA22230.1 282 QCPRCL 287
                 89**96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (527 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1131  (0.0630822); expected 358.6 (0.02)
Passed bias filter:                      626  (0.0349155); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.30s 00:00:00.90 Elapsed: 00:00:00.47
# Mc/sec: 3359.50
//
Query:       EEA22231.1  [L=126]
Description: hypothetical protein PMAA_060100 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (126 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       359  (0.0200234); expected 358.6 (0.02)
Passed bias filter:                      269  (0.0150036); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.37u 0.26s 00:00:00.63 Elapsed: 00:00:00.41
# Mc/sec: 925.67
//
Query:       EEA22232.1  [L=419]
Description: hypothetical protein PMAA_060110 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
  ------ inclusion threshold ------
       0.16   10.2  10.6        0.2    9.8  10.6    1.1  1  Nop14        Nop14-like family
       0.49    8.6  10.1       0.21    9.8   6.6    2.0  2  CDC45        CDC45-like protein


Domain annotation for each model (and alignments):
>> Nop14  Nop14-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8  10.6   2.3e-05       0.2     348     403 ..     230     292 ..     208     350 .. 0.50

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 2.3e-05
       Nop14 348 eeededdfeedddlveseseeeeeeeeedeeeeedeeeee.eeeededdlsdlese..........e 403
                 e++d + +eed+d v s++eeee+++++d++++e+e+++e e e+ +++l++               
  EEA22232.1 230 EDDDGQ-EEEDEDYVPSDEEEEEKKKDSDMDNDESEDDSEgEMEDIQSELQS---LsldeptpptaP 292
                 222222.233333444444443333333333333333332122222222222...112123333331 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.1     0.047   4.2e+02     318     335 ..      88     105 ..      84     106 .. 0.91
   2 ?    9.8   6.6   2.4e-05      0.21     132     220 ..     229     349 ..     206     359 .. 0.40

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.047
       CDC45 318 hWsLydSmlhssYvaskL 335
                 hW+L d  lh +Yv  +L
  EEA22232.1  88 HWTLADNTLHINYVRGQL 105
                 **************9876 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 2.4e-05
       CDC45 132 sdeedeeeeeeddd..deeeeeeeeedeedeeedeeeskkkrk....sksdeeee..................sddddersrkrrrse........... 195
                 + e+d+ +eeed+d   ++eeeee+++++d ++de+e++++ +    +   +  e                  s  d+ ++ ++++++           
  EEA22232.1 229 V-EDDDGQEEEDEDyvPSDEEEEEKKKDSDMDNDESEDDSEGEmediQ---S--ElqslsldeptpptaptdpS--DEAETGSKSKRSflyrlaqtlai 319
                 2.2232222222222322222222222222222222221111111111...1..11123333345566665322..22333333333345667777766 PP

       CDC45 196 ...psakklrrq.....lkkerrkyeavlekyy 220
                    +++++         + ++r+k++++++ y 
  EEA22232.1 320 dpnTNSRA---LyldpwSTSQREKMKQIVQIYV 349
                 54422222...1223445556666666555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (419 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1267  (0.0706676); expected 358.6 (0.02)
Passed bias filter:                      641  (0.0357521); expected 358.6 (0.02)
Passed Vit filter:                        95  (0.00529868); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.32s 00:00:00.97 Elapsed: 00:00:00.49
# Mc/sec: 2552.87
//
Query:       EEA22233.1  [L=72]
Description: hypothetical protein PMAA_060120 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (72 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       994  (0.0554409); expected 358.6 (0.02)
Passed bias filter:                      459  (0.025601); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.41u 0.28s 00:00:00.69 Elapsed: 00:00:00.45
# Mc/sec: 485.80
//
Query:       EEA22234.1  [L=1181]
Description: carbamoyl-phosphate synthase, large subunit [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.1e-107  358.4   0.0      1e-84  283.3   0.0    2.2  2  CPSase_L_D2      Carbamoyl-phosphate synthase L chain, ATP bi
    5.2e-41  139.8   0.0    1.3e-40  138.5   0.0    1.8  1  CPSase_L_D3      Carbamoyl-phosphate synthetase large chain, 
      5e-18   65.4   0.3    9.6e-08   31.8   0.0    2.4  2  Dala_Dala_lig_C  D-ala D-ala ligase C-terminus
    6.2e-18   65.0   0.0      8e-08   32.0   0.0    2.4  2  ATP-grasp        ATP-grasp domain
    3.2e-10   39.8   0.0     0.0012   18.6   0.0    3.1  3  ATPgrasp_Ter     ATP-grasp in the biosynthetic pathway with T
    2.5e-06   27.1   0.0      0.007   15.8   0.0    2.7  2  ATP-grasp_5      ATP-grasp domain
    8.5e-05   22.4   0.0       0.14   11.9   0.0    2.5  2  GARS_A           Phosphoribosylglycinamide synthetase, ATP-gr
    0.00095   18.8   0.0        1.3    8.6   0.0    2.6  2  RimK             RimK-like ATP-grasp domain
  ------ inclusion threshold ------
      0.072   12.5   0.0       0.16   11.3   0.0    1.5  1  GSH-S_ATP        Prokaryotic glutathione synthetase, ATP-gras
      0.085   12.3   0.0        1.1    8.6   0.0    2.5  2  Epimerase        NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> CPSase_L_D2  Carbamoyl-phosphate synthase L chain, ATP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  283.3   0.0   5.8e-88     1e-84       1     210 [.     226     429 ..     226     430 .. 0.99
   2 !   73.0   0.0   1.3e-23   2.3e-20       1     206 [.     763     967 ..     763     971 .. 0.88

  Alignments for each domain:
  == domain 1  score: 283.3 bits;  conditional E-value: 5.8e-88
                  SHHHHHHHHHHTT-BBSSEECSSBSSHHHHHHHHHHH-SSEEEEETTCCTTTTEEEESSHHHHHHHHHHHHHHHHHHHSTS-EEEEE--SSSEEEEEE CS
  CPSase_L_D2   1 DkesakealkkinvpvvpssaapvetleealaiakeigyPviikaafglGGkGmrvarneeelaelvkkalaeakaafgnkqvlvekslkgpkeiEve 98 
                  D++ +++al++in+p+++s a+  +t++eal++a++igyP+i+++a++lGG+G+++a+n+eel++l +++l+ a      +q+lvekslkg+ke+E+e
   EEA22234.1 226 DRDLFAKALNEINIPIAESIAC--NTVDEALEAADQIGYPIIVRSAYALGGLGSGFANNREELKNLSSRSLSLA------PQILVEKSLKGWKEVEYE 315
                  99********************..**************************************************......8***************** PP

                  EEEETTS-EEEEEEEEECCEC..TCCCCEEEES-SS--HHHHHHHHHHHHHHHHHHT-EEEEEEEEEEETTTTEEEEEEEESS--CCHHHHHHHHS-- CS
  CPSase_L_D2  99 vlrDakgnvitvcerenslql..rtqkvievAPsqtLtdeerqalreaavkvvrevgvvgagtveflldpkskeyyviEvNtRlsvesalaekaTGld 194
                  v+rDak+n+itvc++en+++l  +t+++i+vAPsqtL+dee+++lr+aa+k+vr++gvvg+++v+++l+p+  +y viEvN+Rls++sala+kaTG++
   EEA22234.1 316 VVRDAKNNCITVCNMENFDPLgiHTGDSIVVAPSQTLSDEEYHMLRTAAIKIVRHLGVVGECNVQYALQPDGLDYRVIEVNARLSRSSALASKATGYP 413
                  ************************************************************************************************** PP

                  HHHHHHHHHTT--GCG CS
  CPSase_L_D2 195 lvkeaakialgekLee 210
                  l+++aaki+lg++L+e
   EEA22234.1 414 LAYTAAKIGLGHSLPE 429
                  **************97 PP

  == domain 2  score: 73.0 bits;  conditional E-value: 1.3e-23
                  SHHHHHHHHHHTT-BBSSEECSSBSSHHHHHHHHHHH-SSEEEEETTCCTTTTEEEESSHHHHHHHHHHHHHHHHHHHSTS-EEEEE--SSSEEEEEE CS
  CPSase_L_D2   1 DkesakealkkinvpvvpssaapvetleealaiakeigyPviikaafglGGkGmrvarneeelaelvkkalaeakaafgnkqvlvekslkgpkeiEve 98 
                  D+++++++l+ i+v+    ++   +++ ea ++a+++gyPv++++++ l G  m v+++++el+e + +a++ ++    ++ v + k+++g +ei+v+
   EEA22234.1 763 DRHKFSQILDSIGVDQPAWKEL--TSVSEAEKFADTVGYPVLVRPSYVLSGAAMSVIYSHDELKEKLLNASSVSP----DHPVVITKFIEGAQEIDVD 854
                  999***********98877777..9*************************************************6....9****************** PP

                  EEEETTS-EEEEEEEEECCEC..TCCCCEEEES-SS--HHHHHHHHHHHHHHHHHHT-EEEEEEEEEEET..TTTE..EEEEEEESS--CCHHHHHHH CS
  CPSase_L_D2  99 vlrDakgnvitvcerenslql..rtqkvievAPsqtLtdeerqalreaavkvvrevgvvgagtveflldp..kske..yyviEvNtRlsvesalaeka 190
                   +  +   +++    e + +   + ++   v P   L++   ++++  a kv+++ +++g  +++ +  +  + +e    viE N R s++ +  +k+
   EEA22234.1 855 AVGSNGKLILHAV-SEHVENAgvHSGDATLVLPPTSLEQPIMERVKVIAEKVAKAWNITGPFNMQIIKAEnpEGGEplLKVIECNLRASRSFPFVSKV 951
                  **97655555554.455554447******************************************987551233333389****************** PP

                  HS--HHHHHHHHHTT- CS
  CPSase_L_D2 191 TGldlvkeaakialge 206
                   G + + +a k   g 
   EEA22234.1 952 LGTNFIDVATKALIGR 967
                  *****99999876665 PP

>> CPSase_L_D3  Carbamoyl-phosphate synthetase large chain, oligomerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.5   0.0   7.4e-44   1.3e-40       2     122 .]     514     636 ..     513     636 .. 0.97

  Alignments for each domain:
  == domain 1  score: 138.5 bits;  conditional E-value: 7.4e-44
  CPSase_L_D3   2 elkeptdeRifaiaeal.rrglsveeiheltkidpwFLekleelvelekelkkkkk..eldeellreakklGfsDkqiaelleeeeeeevrelrkklg 96 
                  +l++ptd+R +a+ +a+ ++++sv+++h+ltkid+wFL+kl+++v++++elk+  +   l++e+l++akklGfsDkqia +++ ++e++vr+ r + g
   EEA22234.1 514 ALRNPTDRRWLAVGQAMlHENYSVDKVHDLTKIDKWFLYKLQNIVDCQNELKEIGSlfGLKKEILTKAKKLGFSDKQIALCVG-STEDDVRARRLSFG 610
                  799**************999**********************************999**********************9976.78899********* PP

  CPSase_L_D3  97 ilpvykrvDtcAaeFeaetpYlYstY 122
                  i+p +k++Dt+AaeF+a+t+YlY+tY
   EEA22234.1 611 IRPWVKKIDTLAAEFPADTNYLYTTY 636
                  *************************9 PP

>> Dala_Dala_lig_C  D-ala D-ala ligase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.8   0.0   5.4e-11   9.6e-08      29     173 ..     254     396 ..     238     398 .. 0.87
   2 !   31.2   0.1   8.2e-11   1.5e-07      15     153 ..     776     913 ..     769     926 .. 0.80

  Alignments for each domain:
  == domain 1  score: 31.8 bits;  conditional E-value: 5.4e-11
                      HHHHHHC-SSEEEEESSSSTTTTEEEESSGGGHHHHHHHHHTT-SCEEEEE--.ESEEEEEEEEETSSCEEEEEEEEE-SSSSS-HHHHHC.TT CS
  Dala_Dala_lig_C  29 ekveeelgypvfVKpareGSSvGvskveseeelkeaieeafkydekvlvEeai.egreievavlgneklevsevgeivvkkgfydyeakysddk 121
                       +  +++gyp++V++a +   +G   ++++eelk+  +++++   ++lvE+ +   +e+e  v+ + k+++ +v ++      +d    +++d+
       EEA22234.1 254 LEAADQIGYPIIVRSAYALGGLGSGFANNREELKNLSSRSLSLAPQILVEKSLkGWKEVEYEVVRDAKNNCITVCNME----NFDPLGIHTGDS 343
                      456789************99*********************************6679********9888888876654....466666677899 PP

                      -EEESS----HHHHHHHHHHHHHHHHHTT--SEEEEEEEEETTT.EEEEEEEE CS
  Dala_Dala_lig_C 122 aqlevpaklekeveekiqelalkaykaldlrGlaRvDfflteeg.eivlnEvN 173
                      + +    +l++e+++ ++++a+k+ + l++ G + v + l+ +g +  + EvN
       EEA22234.1 344 IVVAPSQTLSDEEYHMLRTAAIKIVRHLGVVGECNVQYALQPDGlDYRVIEVN 396
                      99999999********************************9999445677887 PP

  == domain 2  score: 31.2 bits;  conditional E-value: 8.2e-11
                      EETTHHCH-H-.HHHHHHHHHC-SSEEEEESSSSTTTTEEEESSGGGHHHHHHHHHTT..-SCEEEEE--.ESEEEEEEEEE.TSSCEEEEEEE CS
  Dala_Dala_lig_C  15 lekeeakeekk.ellekveeelgypvfVKpareGSSvGvskveseeelkeaieeafky..dekvlvEeai.egreievavlg.neklevsevge 103
                      +++ ++ke ++    ek  +++gypv+V+p+   S   +s + s +elke + +a +   d+ v++ ++i  ++ei+v  +g n+kl  + v e
       EEA22234.1 776 VDQPAWKELTSvSEAEKFADTVGYPVLVRPSYVLSGAAMSVIYSHDELKEKLLNASSVspDHPVVITKFIeGAQEIDVDAVGsNGKLILHAVSE 869
                      45555555443245678899*******************************99886543399********8899****8888799999999*** PP

                      EE-SSSSS-HHHHHC.TT-EEESS----HHHHHHHHHHHHHHHHHTT--S CS
  Dala_Dala_lig_C 104 ivvkkgfydyeakysddkaqlevpaklekeveekiqelalkaykaldlrG 153
                      +v + g+       s+d++ +  p++le+ + e+++ +a k+ ka +++G
       EEA22234.1 870 HVENAGVH------SGDATLVLPPTSLEQPIMERVKVIAEKVAKAWNITG 913
                      99999886......456666788888888888888888888877777666 PP

>> ATP-grasp  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.0   0.0   4.5e-11     8e-08       2     147 ..     235     385 ..     234     401 .. 0.85
   2 !   30.4   0.0   1.5e-10   2.6e-07       3     146 ..     773     922 ..     771     940 .. 0.87

  Alignments for each domain:
  == domain 1  score: 32.0 bits;  conditional E-value: 4.5e-11
                 HTTT--B-EEEEECCHHHHHHHHHHH-SCEEEEESSS-CTTTTEEEECTCCGHHCHHHHC..GTTCEEEEE----SEEEEEEEEEETTC-EEE--EEEE CS
   ATP-grasp   2 eklglpvprflaveskeeleeaaeelglpvvvKarrlgydGkGqsvvrseedleqaleal..keekvivEefvpfekElsvlvvrsaeGetafypvvet 98 
                 ++ ++p+++ +a ++ +e+ eaa+++g+p++v+ +  +  G G+ + +++e+l+++ +     + +++vE+  +  kE+   vvr+a+ +  ++  +e+
  EEA22234.1 235 NEINIPIAESIACNTVDEALEAADQIGYPIIVR-SAYALGGLGSGFANNREELKNLSSRSlsLAPQILVEKSLKGWKEVEYEVVRDAKNNCITVCNMEN 332
                 6789*****************************.999******************99988778899*********************999999999999 PP

                 EEETTEEE...EEEECEE-SCHHHHHHHHHHH.HHHHHHTSSEEEEEEEEEET CS
   ATP-grasp  99 vqedgilr...lsvapaevsekaqkkaeeiak.kiveeLggvGvfavElFvle 147
                     gi     ++vap++  ++++ +  ++a+ kiv++Lg+vG   v   ++ 
  EEA22234.1 333 FDPLGIHTgdsIVVAPSQTLSDEEYHMLRTAAiKIVRHLGVVGECNVQYALQP 385
                 999988743337899988777766555555444**********8887765555 PP

  == domain 2  score: 30.4 bits;  conditional E-value: 1.5e-10
                 TTT--B-EEEEECCHHHHHHHHHHH-SCEEEEESSS-CTTTTEEEECTCCGHHCHHHHC....GTTCEEEEE----SEEEEEEEEEETTC-EEE--EEE CS
   ATP-grasp   3 klglpvprflaveskeeleeaaeelglpvvvKarrlgydGkGqsvvrseedleqaleal....keekvivEefvpfekElsvlvvrsaeGetafypvve 97 
                 + g+  p +  ++s +e+e++a+++g+pv+v+ +    +G   sv+ s+++l++ l ++     +++v++ +f++  +E+ v +v   +G+    +v e
  EEA22234.1 773 SIGVDQPAWKELTSVSEAEKFADTVGYPVLVR-PSYVLSGAAMSVIYSHDELKEKLLNAssvsPDHPVVITKFIEGAQEIDVDAV-GSNGKLILHAVSE 869
                 678999**************************.99999***********99988776666787899**************98776.679**99999999 PP

                 EEEET....TEEEEEEECEE-SCHHHHHHHHHHHHHHHHHTSSEEEEEEEEEE CS
   ATP-grasp  98 tvqed....gilrlsvapaevsekaqkkaeeiakkiveeLggvGvfavElFvl 146
                 +v++     g+  l++ p+++++ + ++++ ia+k++++ ++ G f + +   
  EEA22234.1 870 HVENAgvhsGDATLVLPPTSLEQPIMERVKVIAEKVAKAWNITGPFNMQIIKA 922
                 999761111567899******************************99877655 PP

>> ATPgrasp_Ter  ATP-grasp in the biosynthetic pathway with Ter operon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0   6.5e-07    0.0012      49     120 ..     360     434 ..     348     444 .. 0.79
   2 !   17.2   0.0   1.8e-06    0.0032       4     117 ..     838     973 ..     836     987 .. 0.72
   3 ?   -1.9   0.0       1.4   2.6e+03      33      73 ..    1080    1120 ..    1056    1124 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 6.5e-07
  ATPgrasp_Ter  49 lielaerlaeefgldglvnvQvrededg..pkLLEiNpRasGGlg.ysalaGvnlpylalklllgleteeveepe 120
                   l  +a ++++++g+ g  nvQ+  + dg  ++++E+N+R s      s ++G  l+y a+k  lg++ +e ++  
    EEA22234.1 360 LRTAAIKIVRHLGVVGECNVQYALQPDGldYRVIEVNARLSRSSAlASKATGYPLAYTAAKIGLGHSLPELPNAV 434
                   557899******************9999889*********96555156777*************98555554444 PP

  == domain 2  score: 17.2 bits;  conditional E-value: 1.8e-06
  ATPgrasp_Ter   4 allvmeyLeg.pEySvDvlaekgevl.aavpRrKekgglq...........elek..deelielaerlaeefgldglvnvQvreded...g...pkL 79 
                   ++++++++eg +E+ vD +  +g+++  av    e+ g++           +le+   e++  +ae++a++ +++g +n+Q+ + e+   g   +k+
    EEA22234.1 838 PVVITKFIEGaQEIDVDAVGSNGKLIlHAVSEHVENAGVHsgdatlvlpptSLEQpiMERVKVIAEKVAKAWNITGPFNMQIIKAENpegGeplLKV 934
                   67888888885699999999999887467777766555545666687886655552246667799****************8544321222324578 PP

  ATPgrasp_Ter  80 LEiNpRasGGlgy.salaGvnlpylalklllgleteeve 117
                   +E N Ras  +   s + G n++++a k+l g++++e++
    EEA22234.1 935 IECNLRASRSFPFvSKVLGTNFIDVATKALIGRDVPEPV 973
                   9*********98526677**************8655544 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 1.4
  ATPgrasp_Ter   33 RrKekgglqelekdeelielaerlaeefgldglvnvQvred 73  
                    R+K   +++ +e  +e   + +++ +++ + g++n+  +++
    EEA22234.1 1080 RAKIPINIEVIEFPKEDKRALREVFQKYDIRGVFNLAKKRG 1120
                    55556666688888888899999************977765 PP

>> ATP-grasp_5  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   3.9e-06     0.007      17      52 ..     232     267 ..     212     271 .. 0.83
   2 !    8.3   0.0   0.00077       1.4      11      51 ..     763     803 ..     756     806 .. 0.91

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 3.9e-06
  ATP-grasp_5  17 elleaygipvvetrlassaeeaveaaeeigypvvlK 52 
                  + l+ ++ip++e++ +++++ea+eaa++igyp+ ++
   EEA22234.1 232 KALNEINIPIAESIACNTVDEALEAADQIGYPIIVR 267
                  446789**************************9876 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.00077
  ATP-grasp_5  11 teaeakelleaygipvvetrlassaeeaveaaeeigypvvl 51 
                  + ++  ++l+ +g++ +  +  +s+ ea + a+++gypv +
   EEA22234.1 763 DRHKFSQILDSIGVDQPAWKELTSVSEAEKFADTVGYPVLV 803
                  567889********************************976 PP

>> GARS_A  Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.8   0.0    0.0014       2.6       5     105 ..     230     323 ..     226     400 .. 0.76
   2 !   11.9   0.0     8e-05      0.14       8     101 ..     769     858 ..     764     882 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0014
                 HHHHHHHHTT--B--EEEESSHHHHHHHHHHHSSSEEEEEESC-GGGT-EEEESSHHHHHHHHHHHCTS-TTCCCCSSEEEEE---S.EEEEEEEEECT CS
      GARS_A   5 fakdllkkagiptaeyeaftdpeeakeyieeatakalVvKadglaagKgvivakseeealkavkeilekkkfGeagekvviEelleG.eEvsllalvdg 102
                 fak+ l++++ip+ae  a + ++ea e  ++ + ++ +v+++   +g g   a+++ee  +  +  l+         ++++E+ l+G +Ev   ++ d 
  EEA22234.1 230 FAKA-LNEINIPIAESIACNTVDEALEAADQIGYPI-IVRSAYALGGLGSGFANNREELKNLSSRSLS------LAPQILVEKSLKGwKEVEYEVVRDA 320
                 5554.689****************************.7777777789999999999998887777775......5689999999999668988888887 PP

                 TEE CS
      GARS_A 103 ktv 105
                 k+ 
  EEA22234.1 321 KNN 323
                 753 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 8e-05
                 HHHHHTT--B--EEEESSHHHHHHHHHHHSSSEEEEEESC-GGGT-EEEESSHHHHHHHHHHHCTS-TTCCCCSSEEEEE---S.EEEEEEEEEC CS
      GARS_A   8 dllkkagiptaeyeaftdpeeakeyieeatakalVvKadglaagKgvivakseeealkavkeilekkkfGeagekvviEelleG.eEvsllalvd 101
                 ++l+ +g+  + ++++t+++ea+++ ++++ ++  v+++ + +g  ++v  s++e  +    +l+  +  +  + vvi +++eG +E+ + a+  
  EEA22234.1 769 QILDSIGVDQPAWKELTSVSEAEKFADTVGYPV-LVRPSYVLSGAAMSVIYSHDELKEK---LLN-ASSVSPDHPVVITKFIEGaQEIDVDAVGS 858
                 68899****************************.99***************99996554...343.44456899*********945888877754 PP

>> RimK  RimK-like ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.5   0.0    0.0015       2.7      12      80 ..     235     304 ..     224     404 .. 0.79
   2 !    8.6   0.0    0.0007       1.3       1      92 [.     761     855 ..     761     882 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0015
                 HHTT-----EEEESS-S-HHHHHHTT-.-SSEEEEE-TTTT--EEEEE-SHHHHHHHHHH...GGG--EEEE CS
        RimK  12 akakikvpntalardeedaekliekiklrfPvvvKsvegsqGikvvlakkeqklkqvlea...lkeailvqe 80 
                    +i++ ++   +  ++a +  ++i  + P++v+s ++  G++  +a+++++lk++ +    l  +ilv +
  EEA22234.1 235 NEINIPIAESIACNTVDEALEAADQI--GYPIIVRSAYALGGLGSGFANNREELKNLSSRslsLAPQILVEK 304
                 44456666666677778888889999..69*************************99554666777777765 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.0007
                 HH-HHHHHHHHHHTT-----EEEESS-S-HHHHHHTT-.-SSEEEEE-TTTT--EEEEE-SHHHHH.HHHHH....GGG--EEEEE--SS-SEEEEE CS
        RimK   1 ardKlkslklLakakikvpntalardeedaekliekiklrfPvvvKsvegsqGikvvlakkeqklk.qvlea....lkeailvqeyieeaenediRv 92 
                 a+d+ k  ++L   +++ p  +   +  +aek+ + +  + Pv+v+ ++   G  + +   +++lk ++l+a     ++ +++ ++ie a++ d+  
  EEA22234.1 761 AEDRHKFSQILDSIGVDQPAWKELTSVSEAEKFADTV--GYPVLVRPSYVLSGAAMSVIYSHDELKeKLLNAssvsPDHPVVITKFIEGAQEIDVDA 855
                 68999999*************999*************..69********99999888888888876256777676556678*********9999865 PP

>> GSH-S_ATP  Prokaryotic glutathione synthetase, ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0     9e-05      0.16      21     139 ..     787     909 ..     782     919 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 9e-05
                 HHHHHHHHHHHSS.EEEEESS--TTTT-EEE-TT-TTHHHHHHHHTTTTTS-EEEEE--GGGGG-EEEEEEETTEE-SEEEEEE--SS-S--...-GGG CS
   GSH-S_ATP  21 keeirafleeqgd.vilKPldgkgGegvfrvkksdpnlksilellteegkepviaqrylpeikeGDkRillvdGepigyalaRvpaegevRs...nlaa 115
                 ++e ++f+++ g  v+++P +  +G+++  + ++d+  +++l++++ +  +pv++ ++++ ++e D+  +  +G+ i +a+    ++  v s    l  
  EEA22234.1 787 VSEAEKFADTVGYpVLVRPSYVLSGAAMSVIYSHDELKEKLLNASSVSPDHPVVITKFIEGAQEIDVDAVGSNGKLILHAVSEHVENAGVHSgdaTLVL 885
                 5677899999998899****************************************************************9886665555442225777 PP

                 TSCEEEEE--HHHHHHHHHHHHHH CS
   GSH-S_ATP 116 ggraeatelterdreiaeelapkL 139
                   +  ++++ er + iae++a++ 
  EEA22234.1 886 PPTSLEQPIMERVKVIAEKVAKAW 909
                 788888888888888888888765 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0      0.24   4.2e+02       9      71 ..     126     187 ..     121     196 .. 0.80
   2 ?    8.6   0.0   0.00064       1.1      12      92 ..    1053    1134 ..    1053    1137 .. 0.78

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.24
                 HHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHCEEEE--TT-HHHHHHHHHHHT-SEEEE- CS
   Epimerase   9 fiGsalvkallekgyevigldrlssasntarledlelveldltdrsalerlfkeeqpdavihl 71 
                 + Gs+ +kal+e+g++ + ++ +  + +t ++   e+++l +t ++ ++ ++++eqpd +++ 
  EEA22234.1 126 YSGSQALKALKEAGVKSVLINPNIATIQTDHKLADEVYYLPVT-PEYVTHVIEREQPDGIFLS 187
                 5699**********99888888866666665555599999999.66799999999***99975 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.00064
                  HHHHHHHHHCTSEEEEEES-STTTTCHHCHHC....EEEE--TT-HHHHHHHHHHHT-SEEEE--S---HHHHHHSHHHHHHHHT CS
   Epimerase   12 salvkallekgyevigldrlssasntarledl....elveldltdrsalerlfkeeqpdavihlAavggvaassedpadfieknl 92  
                  s++v++l+  +y++ + + + +  + ++++++    e++e    d+ al+++f+++++  v++lA     + +  d  +++++n+
  EEA22234.1 1053 SQIVDYLQPLNYKLYAASPEVK-AALESRAKIpiniEVIEFPKEDKRALREVFQKYDIRGVFNLAK--KRGKNLLDEDYVMRRNA 1134
                  6789999999999999999944.444444555799999**************************65..55556666666776665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       457  (0.0254894); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.82u 0.29s 00:00:01.10 Elapsed: 00:00:00.48
# Mc/sec: 7411.39
//
Query:       EEA22235.1  [L=541]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    0.00041   20.4   2.2     0.0041   17.2   0.5    2.7  2  Dehydratase_SU  Dehydratase small subunit
  ------ inclusion threshold ------
        2.6    7.8   9.8      0.059   13.2   1.2    2.5  3  USP8_interact   USP8 interacting


Domain annotation for each model (and alignments):
>> Dehydratase_SU  Dehydratase small subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.1     0.027   2.4e+02      36      89 ..      76     137 ..      39     160 .. 0.66
   2 !   17.2   0.5   4.5e-07    0.0041      45      98 ..     441     494 ..     430     518 .. 0.80

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.027
  Dehydratase_SU  36 kvkaedlritpetLe.lqaqiAesagrkqlaknl..rRaaEl.....vkvpderileiYnal 89 
                     ++++e   +++e ++ lq +iA + + ++l   +  rRaa+l     ++v+ +++++ Y  l
      EEA22235.1  76 RITTEATGVRKEYMKtLQENIAIKREYNALFDRItsRRAADLktaphTAVNSQEVFNHYLDL 137
                     56666667777766536999999999888876654489999933333445556666666444 PP

  == domain 2  score: 17.2 bits;  conditional E-value: 4.5e-07
  Dehydratase_SU  45 tpetLelqaqiAesagrkqlaknlrRaaElvkvpderileiYnalrPyrstkee 98 
                     ++++    a+ A s + + +++ ++ +aE+ +   e++ ++Yn lr  +st ++
      EEA22235.1 441 RAQAWAFAAEAAGSSESDYIQQRIEHGAEMADTASEQLQQVYNILRQEQSTDND 494
                     5667778899999*************************************8754 PP

>> USP8_interact  USP8 interacting
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.1      0.18   1.6e+03      29      55 ..      84     110 ..      68     141 .. 0.63
   2 ?   13.2   1.2   6.6e-06     0.059      11      68 ..     197     256 ..     193     262 .. 0.82
   3 ?   -3.7   0.2         1   8.9e+03      22      45 ..     476     486 ..     459     516 .. 0.49

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.18
  USP8_interact  29 eqkrelellkeyiralrstnpvlrala 55 
                     +k+ +++l+e i+  r  n     ++
     EEA22235.1  84 VRKEYMKTLQENIAIKREYNALFDRIT 110
                    344556677777776666666555553 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 6.6e-06
  USP8_interact  11 qkiaelkkevaeqkqqlseqkrelellkeyiralrstn....pvlraladqlerdevlrWve 68 
                      i++l+k+v + k +l+++++ l++l+++  ++rs+n    p++ral  q +rde+++Wve
     EEA22235.1 197 ALISKLEKTVVRAKAKLAREQHLLKQLQDLQVSTRSANntisPNVRAL--QRTRDELVQWVE 256
                    5699********************************994444444444..5577******97 PP

  == domain 3  score: -3.7 bits;  conditional E-value: 1
  USP8_interact  22 eqkqqlseqkrelellkeyiralr 45 
                    eq qq+ +              lr
     EEA22235.1 476 EQLQQVYN-------------ILR 486
                    22222222.............222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (541 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1177  (0.0656478); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.31s 00:00:00.93 Elapsed: 00:00:00.47
# Mc/sec: 3460.63
//
Query:       EEA22236.1  [L=345]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (345 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       881  (0.0491383); expected 358.6 (0.02)
Passed bias filter:                      234  (0.0130515); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.65u 0.33s 00:00:00.98 Elapsed: 00:00:00.53
# Mc/sec: 1958.47
//
Query:       EEA22237.1  [L=372]
Description: G-patch domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    7.9e-22   76.8   1.4      2e-21   75.5   1.4    1.7  1  DUF4187    Domain of unknown function (DUF4187)
    3.4e-06   26.8   0.5     0.0039   17.1   0.1    2.5  2  G-patch    G-patch domain
  ------ inclusion threshold ------
      0.061   14.2   1.2       0.12   13.4   1.2    1.4  1  DAZAP2     DAZ associated protein 2 (DAZAP2)


Domain annotation for each model (and alignments):
>> DUF4187  Domain of unknown function (DUF4187)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.5   1.4   3.3e-25     2e-21       2      54 .]     321     371 ..     320     371 .. 0.98

  Alignments for each domain:
  == domain 1  score: 75.5 bits;  conditional E-value: 3.3e-25
     DUF4187   2 eleefeeleaeerLeklleyLReeylYCfwCgtkYedeedLeenCPGlteedH 54 
                 el+ef++l+ +e+L++l++y+Re+y YCfwC+++Y+++e+  e+CPG teedH
  EEA22237.1 321 ELNEFDALPSSEKLSRLVMYMREKYWYCFWCKYRYDSAEM--EGCPGVTEEDH 371
                 789*************************************..*********** PP

>> G-patch  G-patch domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   0.1   6.5e-07    0.0039       2      23 ..      77      98 ..      76     100 .. 0.90
   2 !    7.7   0.0   0.00056       3.3      25      44 ..     137     156 ..     136     157 .. 0.93

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 6.5e-07
     G-patch  2 sniGvkmLqkmGWkpGqGLGkk 23
                sn+G++m++k G+k G  LG+ 
  EEA22237.1 77 SNKGFQMMAKLGFKAGDRLGRR 98
                8***************999975 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.00056
     G-patch  25 qGiaePieakikkdraGlGa 44 
                 q +aeP++  ik+dr+G+G 
  EEA22237.1 137 QSRAEPLRLIIKEDRGGIGL 156
                 789***************96 PP

>> DAZAP2  DAZ associated protein 2 (DAZAP2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   1.2   1.9e-05      0.12      34      90 ..      45     107 ..       5     114 .. 0.58

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 1.9e-05
      DAZAP2  34 paaqaalPm......akvesappaaYqapgaaqpqpqtvvveagfDagaRFdkasaasiPPPP 90 
                  +a+a +P       a+ +    a  ++  +   ++ +++ + gf ag R +++s++  PPPP
  EEA22237.1  45 SEAKARIPSkaeraaAEAARRENALNESVLHPSNKGFQMMAKLGFKAGDRLGRRSPPPAPPPP 107
                 344555555322221222222222223333333344778889********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (372 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1565  (0.0872888); expected 358.6 (0.02)
Passed bias filter:                      455  (0.0253779); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.61u 0.31s 00:00:00.92 Elapsed: 00:00:00.49
# Mc/sec: 2272.45
//
Query:       EEA22238.1  [L=549]
Description: triacylglycerol lipase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      3e-85  287.0   0.0    3.9e-85  286.7   0.0    1.0  1  COesterase     Carboxylesterase family
    1.9e-07   31.2   0.1    9.2e-07   28.9   0.1    2.0  1  Abhydrolase_3  alpha/beta hydrolase fold
  ------ inclusion threshold ------
      0.013   15.0   0.0      0.025   14.1   0.0    1.4  1  Peptidase_S9   Prolyl oligopeptidase family


Domain annotation for each model (and alignments):
>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  286.7   0.0   6.5e-89   3.9e-85      20     492 ..      44     520 ..      30     537 .. 0.85

  Alignments for each domain:
  == domain 1  score: 286.7 bits;  conditional E-value: 6.5e-89
                 STCSEEEEEEEEESSB---GGGTTS--BE----SSEEECBS---BESEECSSSSSCGHHCHHHBES---EEEEEEESSSSSTTSSEEEEEEE--STTTS CS
  COesterase  20 ksekevdaFlGiPYAepPvgelRFkkPepaepwtgvrdAtkfspaCpqnaeksekeekeleawvsEDCLyLnvytPkekkeakkklPVlVwihGggfqt 118
                 k+++ v +++G++YA+pP+g+lRF+ P+ +    +v dAt++++ C+++     +++      +sEDCLy++vy+P+++ ++++ lPV+Vwi Gggf  
  EEA22238.1  44 KQDNGVSSWKGMRYAAPPTGSLRFAGPQDPLVQFDVQDATSHGALCISTGAYPTPNN------QSEDCLYVDVYAPTNA-TNSTPLPVFVWIQGGGFNG 135
                 34458*********************************************7666666......8*************97.666777************9 PP

                 -BGCGS-THHHHHHH..TSEEEEE----HHHHH-B-SS..TTSBS-HHHHHHHHHHHHHHHHGGGGTEEEEEEEEEEETHHHHHHHHHHHS.GGGT... CS
  COesterase 119 gsaseydgsaLaaeg..nvivVtinYRlGvlGFlstgd..eeapGNvGllDqvlALrWVkenIasFGGdpervtlfGesAGaasvslllls.plsr... 209
                   + +ydg+ L++    n++vVt+nYR+G++GFl+  +  ++ + N Gl+D++  L+WV++ Ia+FGGdp +vt+ G+sAGa ++ lll     s+   
  EEA22238.1 136 LANANYDGTGLIEASefNIVVVTFNYRVGPYGFLASREveQSGSLNNGLKDMIKLLQWVHKYIAQFGGDPTHVTIGGDSAGAGAITLLLSAyGGSNqld 234
                 88899******887777*******************663377777*****************************************9998643344455 PP

                 TSBSEEEEES--TTSTTTSBSHHHHHHHHHHHHTTS-CSSHHHHHHHHHCS-HHHHHHCCGG..SSSSSSTTC-SSS-B--SSSSSS-HHHHHHCGC.. CS
  COesterase 210 glfkraIlqSGsalspwaiqkkarkrakklakkvgckassskelveclrsksaeelldaqek..aleasssklvsfaPvvdgdflpekPeellkseg.. 304
                 glf+ a+++S  ++ p  + ++++ ++++l +++gc  ++s + ++clr+ + + l + +++    +   s+l++ +P++d++++++   +l+ + +  
  EEA22238.1 235 GLFHAAVAES-QSFGPQLTVSESQFQFDNLTERTGC--ADSMHPLKCLRNLDINALQKENKEipYPSGVLSPLYPYGPTIDNNLVSNYTISLFGEGKfm 330
                 8*********.688888999999*************..888999****************99664455678999*********************77** PP

                 CSEEEEEEETTTTHHHHCCHSTTTSSSSHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHS...TTTSSTCHHHHHHHHHHHHHHHHTHHHHHHHHHH CS
  COesterase 305 kvplliGvnkdegllflaylldkeksvkkkeeklsesllkdelyleaekkeelseaikeeyt...deadrddaeksrkallelltdvlfkapvlrtakl 400
                 k+p+++G  ++eg+ f   ++++           +++ l+d++ +    +e+   +i ++y+   d++  + a k+ + ++++++++ +++p + ++++
  EEA22238.1 331 KIPVIFGDDTNEGTVFTPHNTST--------VARADEFLSDNFPFL---NETELSTINSMYMsspDDPVYSGAGKYWQGVSNAYGEMRYICPGIYLTTA 418
                 *****************955554........344445566777777...689999*******5444444567789999****************99999 PP

                 HH...HTT-SEEEEEEE--STTSSSTTTGSSBTTTTHHHHTTGGGTSGCS....S-HHHHHHHHHHHHHHHHHHHHSSTTS...TTSS----B..TTTB CS
  COesterase 401 ha...srgspvYlYsfdyrnssskkpkwmgvvhgdeleyvfglpllekee....ftkedeklsrkmmtywtnFaktgnPnk...eeeekWpky.tkeee 488
                 +     +++ ++ Y++    s+ +     g+ h+ e+  ++g  ++ +++    +++  e++   m  ywt+F+++ nPn    ++ ++W+   +  e+
  EEA22238.1 419 YNndsTTRNTIWNYHYAVLDSTAN-STGYGTRHTIEVNAIWGPDYVGSSSapksYSTTNENIVPLMQGYWTSFIRSYNPNTyraAGAPEWKVWgDGGER 516
                 98544445559*****98885554.4579**************999999999989999***********************999999999988333333 PP

                 EEEE CS
  COesterase 489 kylk 492
                  +++
  EEA22238.1 517 LFIR 520
                 3333 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.9   0.1   1.5e-10   9.2e-07       2      84 ..     126     219 ..     125     254 .. 0.84

  Alignments for each domain:
  == domain 1  score: 28.9 bits;  conditional E-value: 1.5e-10
                    EEE--STTTS--TTTTHHHHHHHHHHHTSEEEEEE---TT...........TS-TTHHHHHHHHHHHHHHHTHHHHTETTCEEEEEEETHHHHH CS
  Abhydrolase_3   2 vyfHGGGfvlgsldthdalcrelakelgavvvsvdYrlAP...........ehpfPaavedalaalrwlaeqawelgadpsrivlaGdSaGGnl 84 
                    v++ GGGf     + +d +    a+e ++vvv  +Yr  P              +   ++d+++ l+w+++  +++g dp++++++GdSaG+  
     EEA22238.1 126 VWIQGGGFNGLANANYDGTGLIEASEFNIVVVTFNYRVGPygflasreveqSGSLNNGLKDMIKLLQWVHKYIAQFGGDPTHVTIGGDSAGAGA 219
                    8999*****99999998888888***************995555544442224678899*************99*****************864 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   4.2e-06     0.025      13     108 ..     152     256 ..     146     284 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 4.2e-06
                   CT-EEEEE--TTSST...THCHHHHTTSGGGGHHHHHHHHHHHHHHHHTTS--GGGEEEEEETHHHHHHHHHH......HH-GGG-SEEEEESE--- CS
  Peptidase_S9  13 rGyvvvvanirGsgg...yGeafhdagkrklgqnefdDfiaaaealakegyvdserlaitGgSyGGyltgaal......nqrpdlFkaavaevpvvd 100
                    ++vvv  n+r + +    +++ +++g+ ++g +++  +++++ + ++++  d++++ i G S+G   +  +l      nq + lF+aavae   + 
    EEA22238.1 152 FNIVVVTFNYRVGPYgflASREVEQSGSLNNGLKDMIKLLQWVHKYIAQFGGDPTHVTIGGDSAGAGAITLLLsayggsNQLDGLFHAAVAESQSFG 248
                   578999999998885344589999*****************************************75554443233333577889999999877666 PP

                   CCCHHCST CS
  Peptidase_S9 101 vlrydsdt 108
                      + s++
    EEA22238.1 249 PQLTVSES 256
                   66666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (549 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       310  (0.0172904); expected 358.6 (0.02)
Passed bias filter:                      268  (0.0149478); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 3724.64
//
Query:       EEA22239.1  [L=917]
Description: rRNA maturation protein (Nop14), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   5.8e-293  974.4  31.9   7.2e-293  974.1  31.9    1.1  1  Nop14     Nop14-like family


Domain annotation for each model (and alignments):
>> Nop14  Nop14-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  974.1  31.9    4e-297  7.2e-293       2     875 .]      51     901 ..      50     901 .. 0.89

  Alignments for each domain:
  == domain 1  score: 974.1 bits;  conditional E-value: 4e-297
       Nop14   2 esirekfNpFevkvn..keKfeVlgrkvkg...ekgrpgvsrskaeekRkktLlkeyqrrnKsggflDrRfGEnDptmtpeekmleRfarEkqrkakkk 95 
                 ++ire+fNpFe+k    + Kf+V++r+  +   +  rpgv++s +ee+R++tLlke+++rnK+gg++DrRfGEnDptmtpee+++eRfarE+qrk++k+
  EEA22239.1  51 AKIREQFNPFEIKAPsrNAKFDVTTRDGSSkagNYSRPGVTKSLGEERRRETLLKELHSRNKTGGIMDRRFGENDPTMTPEERAAERFARESQRKMRKE 149
                 79************99999******98777555779*************************************************************** PP

       Nop14  96 slFnLe..ddeee.eLtHyGqsLsel........ddfddedl..edddddeeeeegkldakrvreahf...gggedeeeee..eeeeperkkskkevme 176
                 +lFnLe  dde e eLtH+G+sL ++        ddf+++d+   + +ddee+ +++++a  v+++     g  ++++  +  +e ep rkk+k+evm+
  EEA22239.1 150 NLFNLEedDDE-ElELTHGGRSL-SFgdainlngDDFAENDIngGESSDDEESSRKRKRAAAVEDEVDdmdGMASEDD--DeaDETEPLRKKTKAEVMK 244
                 ******64444.36*********.5558889999******99876666666666666666666655444432222222..246999************* PP

       Nop14 177 EvIaKSKlhKaeRqkekeedeelreeLDkelkdlrsllsstkkpkseeakkeeeke.kkekks.....agkdkeeaddeYDklvreLafdkRAkPsdRt 269
                 EvIaKSKl+K+eRqk+ke+d++lr+eLDk l+++++l+++ k+p+++++   e+++  +   +     +gkd++ead eYDk+++++afdkR++P+dRt
  EEA22239.1 245 EVIAKSKLYKYERQKAKEDDDDLRAELDKGLPEIFELMRGVKPPPKTPEPPREDAAiMNP--DraallNGKDRAEADVEYDKRLKQMAFDKRSAPTDRT 341
                 ****************************************88887755544444443323..145899******************************* PP

       Nop14 270 KteEElakeekerLeklEeeRlkRMrgeedeeeeeekkkkkkkeasaDdldddfvleeeeeeeefglgkglkataeee.eeededdfeedddlvesese 367
                 KteEE+a+ee+erL++lE eRl+RMrg+ed+e+e++ ++++      +d + df+ +   ++++fgl + ++++a++e ++ededdf++dddlv+ +s+
  EEA22239.1 342 KTEEEKAQEEAERLKRLELERLRRMRGDEDSESEAGGADDELV----EDEGADFIPD---DAKAFGLTSAVETEARRElDVEDEDDFIIDDDLVDMDSD 433
                 ***************************9888888877766555....8889999998...5889*******87676777******************** PP

       Nop14 368 eeeeeeeedeeeeedeeeeeeeeededdlsdleseeeeeedeleeel..leeekkaaeekkekkkkkkkseekakeelpytfpcPesheellellekre 464
                 e+ +  e+dee e++e e+e+e                 +de++++l  l+ +++          +k+  + k+++ l+yt+pcP+sh+e+l++l+  +
  EEA22239.1 434 ENLSFIESDEEMEDSEMESEDE--------------GLMDDEFSKSLknLVGTES---------GSKNVPTGKTDDGLAYTYPCPQSHDEFLAILK--D 507
                 9999999999999999987654..............3445566444322222221.........2234455556677*******************..8 PP

       Nop14 465 isaedlptvvqRIralhhpsLaeeNKeklqkflavLlqhiaylasqeeappfailesLvrhlhsLaksfpeeaaeafrekLkemqkelekklakgkkkt 563
                 ++a+d+p++vqRIral+hp+L+++NK+kl++f++v+++h+ y+a+q+ + +f+i+e+L+rh+hs+ak+++e +a+afr++L+em+ e++++l +g    
  EEA22239.1 508 VTAKDIPVIVQRIRALYHPRLHSDNKSKLGVFSKVIVDHVVYMANQTGSISFNIIENLLRHIHSMAKTNSEPVAHAFRNHLREMAVERPLNLLPG---- 602
                 8**********************************************9988********************************************.... PP

       Nop14 564 wPslsdLilLkligliFptSDfrHpVvtPallliaeyLgqarirslsdlasglflctlvlqyqslSkRyvPEvinfllnlllllapkkskkkvpgvfpv 662
                      dL+lL+ + +iFptSD++HpVvtPa l+ia+yLgq+ +++ sdla+g++l+ l l+yq+l+kRy+PE++n++l++++ll+p+ ++ +  g + +
  EEA22239.1 603 -----DLVLLTGVMTIFPTSDHFHPVVTPANLCIARYLGQSAVNNTSDLATGAYLAALSLEYQTLAKRYMPEFMNYCLSAICLLSPTPAT-QQVGFVLL 695
                 .....*********************************************************************************9877.55555555 PP

       Nop14 663 kevkpsellelkeleekskkekkqrklslsdllkeesskeeseqlklsllstalsllekfaelyseksafveifepilkllkklklkkkklpeelqekl 761
                 ++   +e+l+l++++    ++++ rk+s++d+++ e++k++se+lk+sl+st++sll+++a+l+++ksa++eif+ ++ +l++lk + +k ++ l++++
  EEA22239.1 696 RD--SKESLRLESSS----TSSEIRKISFWDVVA-EDAKASSEDLKISLISTFVSLLDAAADLWADKSAYIEIFTSAKPILQHLKKSFTKSSSPLSTQI 787
                 66..35645555333....33445**********.778899********************************************99************ PP

       Nop14 762 eellaklerllkkalesRrpLelqkhkplaiktlePkFeeeydpdkkydpdreraelaKLkaelKkErKGAiRELRKDaqFlareklkekkekdaeyek 860
                 +++l+kl++++ +++++RrpL l++h+plaik+ +PkFee+++pdk+ydp+reraelaKLkae+K+ErKGA+RELRKDa+F+are+lkekkekda+yek
  EEA22239.1 788 TTTLHKLKTSSTQSQHTRRPLLLHNHRPLAIKQSIPKFEEDFNPDKHYDPNRERAELAKLKAEHKRERKGAMRELRKDANFVAREQLKEKKEKDAAYEK 886
                 *************************************************************************************************** PP

       Nop14 861 kvkrivaelqseege 875
                 k++r++ae+q+eeg+
  EEA22239.1 887 KYRRLIAEIQGEEGR 901
                 *************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (917 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1393  (0.0776954); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.82u 0.33s 00:00:01.14 Elapsed: 00:00:00.48
# Mc/sec: 5694.19
//
Query:       EEA22240.1  [L=362]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
  ------ inclusion threshold ------
      0.014   15.5   0.0      0.026   14.6   0.0    1.5  1  TAN          Telomere-length maintenance and DNA damage repai
       0.52    9.8   7.6       0.98    8.9   7.6    1.4  1  Osteopontin  Osteopontin
        8.8    5.6   5.8         15    4.8   5.8    1.3  1  NOA36        NOA36 protein


Domain annotation for each model (and alignments):
>> TAN  Telomere-length maintenance and DNA damage repair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.0   4.4e-06     0.026       4      68 ..      94     163 ..      91     183 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 4.4e-06
         TAN   4 alrlLssskikeRnkaldeLkhllsskrn.ktsls..dlkdkawheifeaLfklvekEkeaylkkkk..s 68 
                 +l++L s++  +Rn ald +  l++s+   + +ls    + +++++i++ L++++++ ++ y+ + +   
  EEA22240.1  94 LLEDLTSKNKQQRNRALDAIHFLFASRALsRVTLSprVRDISTYKAIVDCLCNFLDEHTTEYITTDSpiL 163
                 6899**********************9766444447678889********************88766552 PP

>> Osteopontin  Osteopontin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   7.6   0.00016      0.98      54      86 ..     270     302 ..     255     312 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00016
                  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Osteopontin  54 lpsksneshdhvDdvDddddddhvdsqdsvdsd 86 
                  + s   eshd  D+ Ddddddd + + +  dsd
   EEA22240.1 270 MGSMIEESHDLDDNGDDDDDDDGAHDDEDADSD 302
                  568889****99999999999977766666776 PP

>> NOA36  NOA36 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   5.8    0.0025        15     267     296 ..     278     300 ..     257     311 .. 0.49

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0025
       NOA36 267 ddeddegdedddddddeedddeeeddedee 296
                 +d dd+gd+ddddd  ++d+       d +
  EEA22240.1 278 HDLDDNGDDDDDDDGAHDDE-------DAD 300
                 22222222222222222222.......222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (362 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       492  (0.0274416); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.42
# Mc/sec: 2582.66
//
Query:       EEA22241.1  [L=693]
Description: origin recognition complex subunit 3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.8e-36  123.8   0.0    2.7e-33  115.5   0.0    2.6  2  ORC3_N    Origin recognition complex (ORC) subunit 3 N-termin
    1.7e-25   89.7   0.1    9.7e-15   54.9   0.0    2.7  2  ORC_WH_C  Origin recognition complex winged helix C-terminal
  ------ inclusion threshold ------
       0.16   11.5   0.6         13    5.3   0.0    2.7  3  SseC      Secretion system effector C (SseC) like family
       0.57   11.0   3.7       0.52   11.1   0.7    2.5  2  PDGF_N    Platelet-derived growth factor, N terminal region


Domain annotation for each model (and alignments):
>> ORC3_N  Origin recognition complex (ORC) subunit 3 N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.5   0.0   5.9e-37   2.7e-33      13     332 .]      50     338 ..      38     338 .. 0.88
   2 ?   -2.2   0.1      0.39   1.7e+03     110     136 ..     456     486 ..     425     547 .. 0.47

  Alignments for each domain:
  == domain 1  score: 115.5 bits;  conditional E-value: 5.9e-37
                 .XXXXXXXXX-...-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC-..........-----S--EEEEEBTT-GGGCHHHHHHHHHHH CS
      ORC3_N  13 fksllkdeeks...earfkayqrlWeqikseverlqeelnkkaldslveFvrkqaaervekadetesklesseiptaalllGvNvddheetFesLtesL 108
                 f +ll+ +e+      r +a ++lW++ +++++++ eel + +l+++++Fv++++ e           +    ipt ++ +G Nv +    ++ L ++L
  EEA22241.1  50 FVPLLNGKESAelvDGRKAAFKELWSSQEERCKKVMEELDSGILEDITSFVKTASPE-----------AYGGCIPTSLITIGSNVSALPRLLDILHRRL 137
                 4555544444435678999**********************************9999...........56799************************** PP

                 HHTTS-EEEEE-CCC-SSCHHHHHHHHHHHHHCCH-------------------GGG--HHHHHHHHHHHGS.SSHHHHHTTTT-TSS-SS.--EEEEE CS
      ORC3_N 109 rksvtplvvlLqsrdckalkvalekllsqLmekeeeeeedeaeevsesdakslrksqkslraLkrWYeevtrktserarskkraakaekiqskpvVvil 207
                 + ++  +v lL+s d ++lk++l+++++  + +++   +d  + +   d+   r+  ++l+ L   Y+ v ++                  sk +V+ +
  EEA22241.1 138 TTEKCGQVILLESGDAPNLKAVLKTIIRTAVTSTS--GNDAYQ-NLFTDKSGPRMLPYDLNVL---YQYVLSQ-----------------GSKSLVLAF 213
                 ******************************86543..222333.3344667788888887766...6666662.................1368***** PP

                 S-STTS-HHHHHHHHHHHHHTCTTC-EEEEEEESS-HHHHHHHS-HHHHCCTTEEEEEB--HHHHHHHHHHHTTT-TTSS-EE-HHHHHHHHHHHHCT- CS
      ORC3_N 208 eDlEsfdakVLqdfililseyvselPlvlvlGvATSvsaihgllPaavssklavelFqslsakshlaavldkvlLtpefpfkLsgkvlqvLldiFlehd 306
                 +D E+fd++VL+d++  ls+ v+++Plvl++G+ TSv+   g lP+++ ++l+ ++F    a+ +++ + + +   p+  + L++     L++  + h 
  EEA22241.1 214 RDSEAFDSSVLNDLLSLLSSWVDRIPLVLLFGISTSVELFEGRLPRSTVALLHGKQFEIHEAEGAIDRIYETLQTGPDTKLWLGPYLSTSLIEKARDHF 312
                 *************************************************************************************************** PP

                 --HHHHHHHHHHHHHHHHTT-GGGGG CS
      ORC3_N 307 fSvsafikalklallehFmtqplsvL 332
                  S ++fi+ +k+a++ hF+++pls L
  EEA22241.1 313 QSPEGFIREVKYAYMSHFFANPLSNL 338
                 ***********************965 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.39
                 HTTS-EEEEE-CCC-SS....CHHHHHHHHH CS
      ORC3_N 110 ksvtplvvlLqsrdcka....lkvaleklls 136
                 +s ++   +L+  d++a    + +  e l +
  EEA22241.1 456 DSLKAILTVLRENDMSAplvdIDHYEEELQR 486
                 3333444444444444443332222222221 PP

>> ORC_WH_C  Origin recognition complex winged helix C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.9   0.0   2.2e-18   9.7e-15       1      73 [.     581     655 ..     581     658 .. 0.89
   2 !   35.8   0.0   1.6e-12   7.2e-09      98     140 .]     648     690 ..     645     690 .. 0.94

  Alignments for each domain:
  == domain 1  score: 54.9 bits;  conditional E-value: 2.2e-18
    ORC_WH_C   1 RaaiesaLaepedylrcaleeee..eeeeslaslpdtsilyklyleagrliNvyDwyeaFkqvlekereedkese 73 
                 R  ie+aL+ p dyl++a +e++  e  + +a +p+t++ly+lyle+g+l+Nv+D+++aF+  ++ + +e++++e
  EEA22241.1 581 RFCIERALSTPFDYLASASSEHDrsEGGNLSARQPETALLYQLYLESGSLVNVFDLWKAFSTIICGDGHETERDE 655
                 7789***************88888788889999********************************9888766554 PP

  == domain 2  score: 35.8 bits;  conditional E-value: 1.6e-12
    ORC_WH_C  98 eedeeewekelqarFiralheLellGliketgrkadhvaklvw 140
                  +++e+ e+ ++++F+ra++eL+ lG++k++++k dhv+k +w
  EEA22241.1 648 GHETERDERSALMLFYRAMSELKTLGMMKPSRKKVDHVSKSAW 690
                 5678999**********************************99 PP

>> SseC  Secretion system effector C (SseC) like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0    0.0029        13     190     245 ..      81     179 ..      55     186 .. 0.75
   2 ?    3.5   0.2      0.01        45     256     312 ..     370     428 ..     363     432 .. 0.78
   3 ?   -2.0   0.0      0.47   2.1e+03     176     203 ..     527     554 ..     513     558 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0029
        SseC 190 gkevaeqvskqvlnelakkatkva....................................kavkegv.......vasavakalikavvvaeggngiaqG 245
                  k+v+e  ++++l+ +++ +++++                                    k+ + ++       + +av+k++i++ v++ +gn+++q+
  EEA22241.1  81 CKKVMEELDSGILEDITSFVKTASpeayggciptslitigsnvsalprlldilhrrltteKCGQVILlesgdapNLKAVLKTIIRTAVTSTSGNDAYQN 179
                 4566666666666666666666667777777777777777777777777777777777755555555999999999*********************98 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.01
        SseC 256 kkaaqlqAdtkllravleqlqkvldeaaeeikellesiq..ellksmsqaisqkgdtlq 312
                  +a+   A + +  a l+q+ + +++ ++++kel ++++  ++l++m++ ++++++t+ 
  EEA22241.1 370 GEAESVRALLLDDDALLKQVHESVENGVTQMKELFNTMNtlRSLQTMLELSKMNSNTDL 428
                 5666667777777899999***************9999933469999999999888875 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 0.47
        SseC 176 eaigkaikkaaekagkevaeqvskqvln 203
                 +++++a ++++ek+++e+  + +++++n
  EEA22241.1 527 SGVESAYTELIEKFIEELETSLTSKLTN 554
                 5678899999999999999998888776 PP

>> PDGF_N  Platelet-derived growth factor, N terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.1       1.9   8.7e+03      27      60 ..     379     412 ..     369     424 .. 0.69
   2 ?   11.1   0.7   0.00012      0.52      23      75 ..     483     532 ..     479     534 .. 0.72

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 1.9
      PDGF_N  27 LLeidsvgeedeeseeskhrakkkhsaeslelks 60 
                 LL+ d + ++++es+e+  ++ k+  + +++l+s
  EEA22241.1 379 LLDDDALLKQVHESVENGVTQMKELFNTMNTLRS 412
                 6777777777777777777777776666655554 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00012
      PDGF_N  23 DLqRLLeidsvgeedeeseeskhrakkkhsaeslelkssqlhsrrkrsvveeA 75 
                 +LqRLL  +s +e   +++++   ++ ++++  +++k + +++r+k s ve A
  EEA22241.1 483 ELQRLLATHSSDEP--LHSKHD-DQNTSVKTTIVKDKVNLTKTRKKISGVESA 532
                 8*********9666..333333.333444444557888999999**9999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (693 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       767  (0.0427799); expected 358.6 (0.02)
Passed bias filter:                      519  (0.0289475); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.66u 0.30s 00:00:00.96 Elapsed: 00:00:00.47
# Mc/sec: 4405.49
//
Query:       EEA22242.1  [L=865]
Description: pentatricopeptide repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-05   25.5   0.0        3.3    8.0   0.0    5.2  5  PPR_2     PPR repeat family
     0.0095   16.1   0.5         40    4.8   0.0    4.4  4  PPR       PPR repeat
       0.01   15.9   0.0         18    5.5   0.0    3.4  3  PPR_3     Pentatricopeptide repeat domain
  ------ inclusion threshold ------
       0.13   13.0   0.1         32    5.3   0.0    2.5  2  HypF_C    HypF Kae1-like domain


Domain annotation for each model (and alignments):
>> PPR_2  PPR repeat family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.0     0.056   2.5e+02      10      28 ..     273     291 ..     271     293 .. 0.87
   2 !    6.6   0.0     0.002       8.8      12      33 ..     387     408 ..     381     417 .. 0.84
   3 !    8.0   0.0   0.00074       3.3       6      39 ..     460     493 ..     455     504 .. 0.84
   4 ?   -0.7   0.0      0.38   1.7e+03      35      45 ..     563     573 ..     557     581 .. 0.70
   5 ?    1.1   0.0       0.1   4.5e+02       1      43 [.     599     640 ..     599     644 .. 0.81

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.056
       PPR_2  10 IsglckkgkveeAfklfne 28 
                 I+ l   g++eeA++l++e
  EEA22242.1 273 IDVLHDGGDIEEALQLWEE 291
                 77777889*********97 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.002
       PPR_2  12 glckkgkveeAfklfneMkkrg 33 
                  ++++gk++ A+ +f++M   g
  EEA22242.1 387 SFLNDGKISLALAVFKDMMITG 408
                 699***************7655 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.00074
       PPR_2   6 yNtlIsglckkgkveeAfklfneMkkrglePnsy 39 
                 y + ++ l   g+v++A  + + M +rg++P+++
  EEA22242.1 460 YASWMKKLIGMGEVDSAAAVVELMFERGVRPDAI 493
                 66777888899*********************86 PP

  == domain 4  score: -0.7 bits;  conditional E-value: 0.38
       PPR_2  35 ePnsyTysili 45 
                 + n  T+sil+
  EEA22242.1 563 PANIETFSILL 573
                 45888999887 PP

  == domain 5  score: 1.1 bits;  conditional E-value: 0.1
       PPR_2   1 pdvvtyNtlIsglckkgkveeAfklfneMkkrglePnsyTysi 43 
                 p++  +N+l+ + ++k ++++ ++ f+    r + P+  T+  
  EEA22242.1 599 PNSYYMNHLLYAELRKQRINSLWEKFQLLA-REVAPDLETFAC 640
                 789999*************99999997554.677788888765 PP

>> PPR  PPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0     0.018        83      13      25 ..     279     291 ..     273     294 .. 0.83
   2 !    4.8   0.0     0.009        40       5      27 ..     383     405 ..     381     407 .. 0.86
   3 ?    1.9   0.2     0.073   3.3e+02       5      31 .]     462     488 ..     458     488 .. 0.84
   4 ?   -3.0   0.0       2.6   1.2e+04       2      17 ..     568     583 ..     567     586 .. 0.82

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.018
         PPR  13 nGkleeAlelfke 25 
                  G++eeAl+l++e
  EEA22242.1 279 GGDIEEALQLWEE 291
                 69*********98 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.009
         PPR   5 slIsgycknGkleeAlelfkeMk 27 
                 +l  ++   Gk++ Al +fk+M 
  EEA22242.1 383 ILSTSFLNDGKISLALAVFKDMM 405
                 566788999*************5 PP

  == domain 3  score: 1.9 bits;  conditional E-value: 0.073
         PPR   5 slIsgycknGkleeAlelfkeMkekGi 31 
                 s+++ +   G+++ A  + + M e+G+
  EEA22242.1 462 SWMKKLIGMGEVDSAAAVVELMFERGV 488
                 666667778****************97 PP

  == domain 4  score: -3.0 bits;  conditional E-value: 2.6
         PPR   2 tynslIsgycknGkle 17 
                 t+++l+  y + G+ +
  EEA22242.1 568 TFSILLLHYTRRGDDD 583
                 8999999999999865 PP

>> PPR_3  Pentatricopeptide repeat domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.15   6.7e+02      17      42 ..     380     405 ..     375     415 .. 0.82
   2 !    4.9   0.0    0.0061        27      29      58 ..     471     500 ..     459     502 .. 0.87
   3 !    5.5   0.0    0.0039        18      14      57 ..     565     608 ..     562     611 .. 0.94

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.15
       PPR_3  17 tYthLLtayanagnkklalevlermk 42 
                 +Y  L t + n g+  lal v++ m 
  EEA22242.1 380 DYDILSTSFLNDGKISLALAVFKDMM 405
                 677777889999***********996 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.0061
       PPR_3  29 gnkklalevlermkkkgikPtvvtyNailg 58 
                 g+ + a  v+e m + g++P  +  N i+g
  EEA22242.1 471 GEVDSAAAVVELMFERGVRPDAIHLNGIIG 500
                 67788999******************9997 PP

  == domain 3  score: 5.5 bits;  conditional E-value: 0.0039
       PPR_3  14 dvvtYthLLtayanagnkklalevlermkkkgikPtvvtyNail 57 
                 ++ t+  LL  y + g+ + + +  + +   +i+P+  + N +l
  EEA22242.1 565 NIETFSILLLHYTRRGDDDMVKYLNKCLGDAQIRPNSYYMNHLL 608
                 8999999**********************************998 PP

>> HypF_C  HypF Kae1-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0    0.0072        32       6      37 ..     275     306 ..     272     334 .. 0.89
   2 ?    4.9   0.1    0.0094        42      12      87 ..     779     855 ..     778     862 .. 0.83

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0072
      HypF_C   6 vLAlGaelkntfalakggqallsqhlGdlenl 37 
                 vL  G++ ++++ l +++qa++sq  Gd++ +
  EEA22242.1 275 VLHDGGDIEEALQLWEESQAIISQGEGDIDAY 306
                 7778************************9976 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.0094
      HypF_C  12 elkntfalakggqallsqhlG.dlenletleayeealeeleklleik.pevivcDlhpdylstklaeelaekekleli 87 
                 + kn +a ++ ++a + q  G d+e+l  +++ + +le l++ll +   +++v+ +  d ++t++++++ ++ +++ +
  EEA22242.1 779 QVKNILATLQTKKASILQAQGiDVEHLGEQDRKQYQLEILSELLVMViERTVVVPAGSDQVKTQIVATI-QEMGVPNL 855
                 67999999********999999********************997752668888888888888888887.56666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (865 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       601  (0.0335211); expected 358.6 (0.02)
Passed bias filter:                      475  (0.0264934); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.68u 0.24s 00:00:00.92 Elapsed: 00:00:00.40
# Mc/sec: 6473.14
//
Query:       EEA22243.1  [L=254]
Description: translocation protein (Sec66), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.4e-81  269.7   1.3    1.1e-80  269.4   1.3    1.1  1  Sec66     Preprotein translocase subunit Sec66
       0.01   15.9   0.1      0.021   14.9   0.1    1.5  1  DUF3848   Protein of unknown function (DUF3848)


Domain annotation for each model (and alignments):
>> Sec66  Preprotein translocase subunit Sec66
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  269.4   1.3   1.3e-84   1.1e-80       1     179 [.       4     190 ..       4     191 .. 0.99

  Alignments for each domain:
  == domain 1  score: 269.4 bits;  conditional E-value: 1.3e-84
       Sec66   1 kvslytPliYvavligslatfsslyrkrkakklaelepwFpenlqrdiYlsllhl........ekkkeekvpekvlkAALLrravedirrilklreskp 91 
                 +vsl++P++Y+++ligslatfsslyrkrk++++ +l+pwFp++lqrdiY+sllhl        ++kk+++vpe+vlkAALLrra+edi+r++ +r++k+
  EEA22243.1   4 WVSLAIPFAYLGILIGSLATFSSLYRKRKSARALSLAPWFPSHLQRDIYFSLLHLeqpaaaagKEKKTTAVPETVLKAALLRRAAEDIKRVIAIRDQKQ 102
                 89*************************************************************888889****************************** PP

       Sec66  92 alevllqkGsvgddlwqrfqraekeleeElkdvvqeaealkpgWgqtifqsaneilanealrrrleeiekrkeeekeewekkkadiee 179
                 al+ llq+Gsvgddlwqrf+raeke+eeE++dvv+ea+a++p+Wgq+ifqsa+e+ +n+ +r+r++e++++++ee e+w k++ +i+e
  EEA22243.1 103 ALSLLLQRGSVGDDLWQRFLRAEKEMEEEVRDVVREANAYAPNWGQFIFQSAREMDQNNLFRQRIDEYQSKVSEEVEWWTKRRLEIQE 190
                 ***********************************************************************************99986 PP

>> DUF3848  Protein of unknown function (DUF3848)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.1   2.4e-06     0.021      22      91 ..      72     140 ..      67     143 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 2.4e-06
     DUF3848  22 skppeeilesaYeltvkedilmsleeeelsdeqakaLlksenpLddvyeewekrddsymedlrqtieera 91 
                 +  pe +l++a      edi+ ++   +++ +++  Ll+  +  dd++++++  ++++ e++r+++ e+ 
  EEA22243.1  72 TAVPETVLKAALLRRAAEDIKRVIAIRDQK-QALSLLLQRGSVGDDLWQRFLRAEKEMEEEVRDVVREAN 140
                 5679999****9999*********999875.67999******************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (254 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       968  (0.0539907); expected 358.6 (0.02)
Passed bias filter:                      551  (0.0307323); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.47
# Mc/sec: 1631.85
//
Query:       EEA22244.1  [L=1603]
Description: AAA family ATPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.8e-47  161.1   0.0    7.8e-42  142.8   0.0    3.2  3  AAA              ATPase family associated with various cellul
      2e-09   37.1   0.0    6.9e-09   35.4   0.0    1.9  1  AAA_lid_3        AAA+ lid domain
    2.7e-06   27.3   0.0    7.9e-06   25.7   0.0    1.7  1  IstB_IS21        IstB-like ATP binding protein
    6.5e-06   26.4   0.0    1.6e-05   25.1   0.0    1.6  1  AAA_2            AAA domain (Cdc48 subfamily)
    8.5e-06   26.3   0.0    0.00021   21.7   0.0    3.0  2  AAA_16           AAA ATPase domain
    0.00038   20.5   0.0     0.0015   18.6   0.0    2.1  1  AAA_5            AAA domain (dynein-related subfamily)
    0.00074   19.5   0.0     0.0019   18.2   0.0    1.7  1  Bromodomain      Bromodomain
     0.0025   18.4   1.1       0.13   12.8   0.0    3.2  2  AAA_18           AAA domain
     0.0029   17.7   0.0       0.99    9.5   0.0    2.5  2  Sigma54_activ_2  Sigma-54 interaction domain
     0.0031   17.8   1.3       0.12   12.7   0.2    3.7  3  AAA_22           AAA domain
     0.0044   16.8   0.1      0.014   15.1   0.0    1.8  2  AAA_30           AAA domain
     0.0048   17.3   0.0      0.012   16.0   0.0    1.7  1  RNA_helicase     RNA helicase
     0.0054   16.3   0.0      0.026   14.1   0.0    2.1  2  AAA_25           AAA domain
  ------ inclusion threshold ------
      0.018   15.1   0.0      0.089   12.8   0.0    2.2  1  AAA_14           AAA domain
      0.026   13.7   0.0      0.041   13.1   0.0    1.2  1  TIP49            TIP49 P-loop domain
      0.028   14.0   0.1         12    5.5   0.1    2.8  2  Zot              Zonular occludens toxin (Zot)
      0.048   13.0   0.0       0.13   11.7   0.0    1.7  1  Mg_chelatase     Magnesium chelatase, subunit ChlI
      0.053   13.7   0.0       0.14   12.3   0.0    1.7  1  AAA_33           AAA domain
      0.071   12.8   0.0       0.18   11.5   0.0    1.6  1  RuvB_N           Holliday junction DNA helicase RuvB P-loop d
       0.09   12.5   0.0        2.4    7.9   0.0    2.7  3  Sigma54_activat  Sigma-54 interaction domain
       0.11   12.0   0.0       0.23   10.9   0.0    1.4  1  AAA_7            P-loop containing dynein motor region
       0.12   12.3   0.0       0.27   11.1   0.0    1.6  1  AAA_3            ATPase family associated with various cellul
       0.12   11.2   0.2        8.8    5.1   0.2    2.3  2  TrwB_AAD_bind    Type IV secretion-system coupling protein DN
       0.32   10.8   0.0       0.32   10.8   0.0    3.8  1  AAA_11           AAA domain


Domain annotation for each model (and alignments):
>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  142.8   0.0     1e-44   7.8e-42       1     132 []     588     723 ..     588     723 .. 0.95
   2 ?   -1.9   0.0       5.7   4.2e+03     107     127 ..     822     841 ..     804     844 .. 0.82
   3 !   14.5   0.0   4.8e-05     0.036       2      74 ..     892     964 ..     891    1010 .. 0.78

  Alignments for each domain:
  == domain 1  score: 142.8 bits;  conditional E-value: 1e-44
                 EEEESSTTSSHHHHHHHHHHHH.....THEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHH CS
         AAA   1 vllyGppGtGKTllakavakel.....gvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksrsgseseeeervvnqLlteld 94 
                 vl++GppGtGKTl+a+a+a+++     +v+f+  +g++ lsk+vge+e+++r lf+ea++ + psi+f+DEid la+ rs+++++ + ++v++Ll+ +d
  EEA22244.1 588 VLFHGPPGTGKTLMARALASSVssegrKVTFYMRKGADALSKWVGEAERQLRLLFEEARKTQ-PSIIFFDEIDGLAPVRSSKQEQIHASIVSTLLALMD 685
                 79*******************955555599*******************************9.************************************ PP

                 HTTTSSSTEEEEEEESSGGGSTHHHHS.TTSSEEEETTS CS
         AAA  95 gvkkkeskvivigatnrpdkldpallr.gRfdrkieiel 132
                 g++ + ++vivigatnrpd++dpal+r gRfdr+++++l
  EEA22244.1 686 GMDGR-GQVIVIGATNRPDSIDPALRRpGRFDREFYFPL 723
                 ****7.56****************************985 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 5.7
                 EEESSGGGSTHHHHSTTSSEE CS
         AAA 107 gatnrpdkldpallrgRfdrk 127
                 gat  p++++p l+ +Rf ++
  EEA22244.1 822 GATPLPKSIEPLLR-DRFVEI 841
                 89999*********.9*9765 PP

  == domain 3  score: 14.5 bits;  conditional E-value: 4.8e-05
                 EEESSTTSSHHHHHHHHHHHH.THEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHH CS
         AAA   2 llyGppGtGKTllakavakel.gvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksr 74 
                 l+ G  G+G  +la av +++ g ++ ++++++lls+     e+ + +lf+e+k+++ ps++ i ++     + 
  EEA22244.1 892 LIRGLQGMGQQYLAGAVLHHFeGLHVQSFDLPTLLSDSTRSPEATVVQLFAEVKRHK-PSVIYIPNVQTWYDTV 964
                 78899***************956********************************98.******9998776555 PP

>> AAA_lid_3  AAA+ lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.4   0.0   9.3e-12   6.9e-09       5      38 ..     750     783 ..     749     805 .. 0.80

  Alignments for each domain:
  == domain 1  score: 35.4 bits;  conditional E-value: 9.3e-12
   AAA_lid_3   5 keLAerTeGySGADlaalcreAallAlrrgikei 38 
                 +eLAe+T+Gy GADl alc e+al+A++r  ++i
  EEA22244.1 750 DELAELTKGYGGADLRALCTESALNAVQRQYPQI 783
                 79**************************965443 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.7   0.0   1.1e-08   7.9e-06      49     130 ..     587     672 ..     575     682 .. 0.87

  Alignments for each domain:
  == domain 1  score: 25.7 bits;  conditional E-value: 1.1e-08
   IstB_IS21  49 nivllGpsGvGKshlaialgveavraglsvlfvr...vedLveelkrarrdgklaralkrllkvdllilDdl.gllpldqaeaell 130
                 ++++ Gp+G+GK+ +a al+ +   +g +v+f+    +++L + +  a+r+ +l  + +r ++++++  D++ gl p+ + ++e++
  EEA22244.1 587 GVLFHGPPGTGKTLMARALASSVSSEGRKVTFYMrkgADALSKWVGEAERQLRLLFEEARKTQPSIIFFDEIdGLAPVRSSKQEQI 672
                 68999*************************99853446789999***************************978888877776665 PP

>> AAA_2  AAA domain (Cdc48 subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1   0.0   2.2e-08   1.6e-05       6     105 ..     588     686 ..     584     692 .. 0.85

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 2.2e-08
                 EEEE--TTSSHHHHHHHHHHHTT-....-EEEEEGGG-------THHHHHHHHHTTT-HHHHTTS...EEEEETGGG-------------HHHHHHHHH CS
       AAA_2   6 illlgptgvGktelakalaellfvkkekkliradaselleeeevehlvsrligappgyvgaeegG...ivllDEidKihpkessgadvSregVqrdLLq 101
                 +l+ gp g+Gkt++a+ala+  +  +e + +++ +++ +   ++++ v + + +     + + +    i+++DEid  +p +ss+++  +  ++  LL 
  EEA22244.1 588 VLFHGPPGTGKTLMARALASSVS--SEGRKVTFYMRKGAD--ALSKWVGEAERQLRLLFEEARKTqpsIIFFDEIDGLAPVRSSKQEQIHASIVSTLLA 682
                 689******************98..466667778888877..78888888888877777666666777*************99999999999******* PP

                 HHH- CS
       AAA_2 102 ileg 105
                 +++g
  EEA22244.1 683 LMDG 686
                 **98 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.7   0.0   2.8e-07   0.00021      24     127 ..     585     684 ..     575     697 .. 0.64
   2 ?    0.1   0.0       1.2     9e+02      11      50 ..     876     914 ..     873     955 .. 0.74

  Alignments for each domain:
  == domain 1  score: 21.7 bits;  conditional E-value: 2.8e-07
      AAA_16  24 pelvllsGesGvGKsslvrellralekd..ggif.lrgkcdqlesaipysalaqalareellrqlldeaesaeleawrekleealaavpelagaea.sr 118
                 p+ vl++G++G+GK+ ++r+l+ +++ +  ++ f +r  +d l      s ++  + + + lr l +ea++++++       + la+v++ + ++   +
  EEA22244.1 585 PRGVLFHGPPGTGKTLMARALASSVSSEgrKVTFyMRKGADAL------SKWVGEA-E-RQLRLLFEEARKTQPSIIFFDEIDGLAPVRSSKQEQIhAS 675
                 689********************99999433555677777777......7788888.4.4455565565555554444444444443444444333455 PP

      AAA_16 119 llellkrll 127
                 +  +l +l+
  EEA22244.1 676 IVSTLLALM 684
                 555555555 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 1.2
      AAA_16  11 qLlsalervrsgrpelvllsGesGvGKsslvrellralek 50 
                 q+l+ +e+ r  r + +l++G +G+G   l+ ++l+++e+
  EEA22244.1 876 QMLQEFETSRIFR-PRLLIRGLQGMGQQYLAGAVLHHFEG 914
                 5566667666666.5788********99999999988874 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0     2e-06    0.0015       2     136 ..     588     711 ..     587     712 .. 0.68

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 2e-06
                 EEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--.........--------..G-SEEEEESGGG--HHHHHHHHHHHHSSEEE..- CS
       AAA_5   2 vlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreikngttslvdsplvraar..egeilvlDEveraesevlnsLlslleerrlllee 98 
                 vl  GppGtgK+ +a+ la+ + +e   v ++ +  ++ l  ++    g+++++   l ++ar  +++i+++DE++ + +   ++  ++       l  
  EEA22244.1 588 VLFHGPPGTGKTLMARALASSVSSEGRKVTFYMRKGADAL-SKWV---GEAERQLRLLFEEARktQPSIIFFDEIDGLAPVRSSKQEQIHASIVSTLLA 682
                 8999******************555555555555455555.5666...689999999**99999999********977655444444443333333333 PP

                 SSSEEE---......-EEEEEESS--.-TT-TTHHHHT CS
       AAA_5  99 ggelvkaknddllerfrviatanpldrslnelspalrs 136
                 +   ++ + +     + vi+++n++d    +++palr+
  EEA22244.1 683 LMDGMDGRGQ-----VIVIGATNRPD----SIDPALRR 711
                 3333333332.....77777777777....77777765 PP

>> Bromodomain  Bromodomain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0   2.6e-06    0.0019      39      70 ..    1170    1201 ..    1166    1208 .. 0.91

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 2.6e-06
                   HHHHHHHHHTT--SSHHHHHHHHHHHHHHHHH CS
  Bromodomain   39 LstIkkklesnkYksladfeadlkllfsNark 70  
                   + tI+k+l ++ Yk+++df ad+k++ + ar 
   EEA22244.1 1170 IVTIEKRLSNGYYKRPKDFLADIKRIAKDARS 1201
                   669************************99986 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   1.2      0.52   3.9e+02      25      69 ..      52      96 ..      38     126 .. 0.81
   2 !   12.8   0.0   0.00018      0.13       1      36 [.     588     624 ..     588     661 .. 0.82

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.52
      AAA_18 25 gvnlrdvakenglllevdpealdeskrldedkldklldaleenss 69
                g    d++++++ll evd+  ++es+++d++ ++k+ ++l++  +
  EEA22244.1 52 GSDDDDIVSDDDLLSEVDELSYEESEEEDDGTVEKNARGLRRRKA 96
                66778999**************************99999998655 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 0.00018
      AAA_18   1 IlltGtpGvGKttlakeLskrlgf.gvnlrdvakeng 36 
                 +l  G+pG+GKt +a++L+++  + g++++++ +++ 
  EEA22244.1 588 VLFHGPPGTGKTLMARALASSVSSeGRKVTFYMRKGA 624
                 5778**************9997557999999888765 PP

>> Sigma54_activ_2  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.5   0.0    0.0013      0.99      24      76 ..     588     643 ..     584     678 .. 0.71
   2 ?    5.5   0.0     0.023        17      15      79 ..     882     958 ..     869     962 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.0013
                      EEEEEETT--HHHHHHCC--T..TS-EE--SSTTHHHH-HHHHHHHTTTSE.EEEE CS
  Sigma54_activ_2  24 vfltGekGsgkelvArlLhkn..sgpwleifvverlaklpldlleqakggt.Lylk 76 
                      v+  G++G+gk+l+Ar+L+++  s++    f + ++a++ ++++ +a+ ++ L+++
       EEA22244.1 588 VLFHGPPGTGKTLMARALASSvsSEGRKVTFYMRKGADALSKWVGEAERQLrLLFE 643
                      8899**************87522556667788889999998888776433213333 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.023
                      HHHHT-SS-EEEEEETT--HHHHHH.CC--TTS-EE--SSTTHHHH-H........HHHHHHT...TTSEEEEEE-T CS
  Sigma54_activ_2  15 eqaaqsklpvfltGekGsgkelvAr.lLhknsgpwleifvverlaklp........ldlleqa...kggtLylkdia 79 
                      e  +     +++ G +G g+++ A+ +Lh+++g  ++ f++ +l +           +l++++   k+ ++y+++++
       EEA22244.1 882 ETSRIFRPRLLIRGLQGMGQQYLAGaVLHHFEGLHVQSFDLPTLLSDStrspeatvVQLFAEVkrhKPSVIYIPNVQ 958
                      55555667799*************8359******9999999887753323334444333333344488999999887 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0         3   2.2e+03      96     113 ..     365     384 ..     338     424 .. 0.70
   2 !   12.7   0.2   0.00016      0.12       9      39 ..     589     613 ..     585     703 .. 0.64
   3 ?   -2.3   0.0       6.6   4.9e+03      38      91 ..     785     839 ..     767     880 .. 0.61

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 3
      AAA_22  96 iiDEaqhlrseealeeL....r 113
                  +DEa+ l  +e l++L    r
  EEA22244.1 365 YVDEAEEL--AEELQDLqpsrR 384
                 57777777..566666543322 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 0.00016
      AAA_22   9 vvtGesGtGKTtllrrlleqldeeakaeeer 39 
                 + +G++GtGKT+ +r l+++   e      +
  EEA22244.1 589 LFHGPPGTGKTLMARALASSVSSE------G 613
                 679***************998543......3 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 6.6
      AAA_22  38 erpevvfvtlpsst.sskdllrellralglelkaerlsseell.ealeqalrarav 91 
                 ++++ ++++++  + ++kd++  + +++ ++  + + s    l + +e  lr+r+v
  EEA22244.1 785 KSSQKLLIDPKTIEvTPKDFMISIKKIVPSSERS-TSSGATPLpKSIEPLLRDRFV 839
                 4444455555555567777777777777776666.333333333555555555544 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.1       6.7     5e+03      45     105 ..     180     239 ..     151     242 .. 0.56
   2 !   15.1   0.0   1.9e-05     0.014      21      63 ..     588     628 ..     576     673 .. 0.78

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 6.7
      AAA_30  45 aggrviglAptgkaAkvLaeelgieastiakllkrlk..grarlepgtllivDEagmvdtkql 105
                 +g++v  +     aA++  +++  +++t+a  +      ++ +  ++++  +DE++ + ++ql
  EEA22244.1 180 SGRHVETIEEGVVAAAQAPRSTRRASKTVAGAT---PieEEDENGSNNVRSIDESAETKQSQL 239
                 233333333333333333344444555555544...043445566678888888877777666 PP

  == domain 2  score: 15.1 bits;  conditional E-value: 1.9e-05
      AAA_30  21 avltGpAGtGKttalkalreaweaaggrviglAptgkaAkvLa 63 
                 ++ +Gp+GtGKt + +al+  + ++g++v  +  +g  A++L+
  EEA22244.1 588 VLFHGPPGTGKTLMARALASSVSSEGRKVTFYMRKG--ADALS 628
                 5789*************************9876554..44455 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   1.6e-05     0.012       1      41 [.     588     625 ..     588     659 .. 0.77

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 1.6e-05
  RNA_helicase   1 iwlyGpsgeGKStlakeLakallkklklkkkdsvysrnped 41 
                   ++++Gp+g+GK+++a+ La++++    + +k ++y+r+ +d
    EEA22244.1 588 VLFHGPPGTGKTLMARALASSVS---SEGRKVTFYMRKGAD 625
                   689********************...455778899865543 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.1   0.0   3.4e-05     0.026      36     107 ..     588     657 ..     581     707 .. 0.69
   2 ?   -1.9   0.0       2.8   2.1e+03     106     151 ..     915     957 ..     881     962 .. 0.66

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 3.4e-05
      AAA_25  36 allaGapgtGKttlaldlalava.tGkpwlgpvapeqgkVlyvsaEdsedelrrRlravgealrddarllvld 107
                 +l+ G+pgtGKt +a  la +v+ +G++++  ++    +   +++E  + +lr  ++++++++  ++  ++  
  EEA22244.1 588 VLFHGPPGTGKTLMARALASSVSsEGRKVTFYMRKGADALSKWVGEAER-QLRLLFEEARKTQ--PSIIFFDE 657
                 5789*******************99*99988777766677777777777.7777777666665..44444444 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 2.8
      AAA_25 106 ldlagveslpLfakdrggtl.ltadvdaleaaieevegvrlvviDpl 151
                 l++   +s +L ++ +++t+  +a v +l a++++ +++ +++i ++
  EEA22244.1 915 LHV---QSFDLPTLLSDSTRsPEATVVQLFAEVKR-HKPSVIYIPNV 957
                 333...3334444445555546677899*******.88999999665 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   0.00012     0.089       5     104 ..     588     702 ..     585     725 .. 0.71

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 0.00012
      AAA_14   5 lvitGaRrvGKTtllkqlikell.vkkesilyinldderdkk.ladpekllelileklkeekktylflDEiqev............pewekalkslvd. 88 
                 ++  G+  +GKT +++ l+++     ++ ++y+    + ++k   + e+ l+l++e++++ + +++f+DEi  +             ++ ++l  l+d 
  EEA22244.1 588 VLFHGPPGTGKTLMARALASSVSsEGRKVTFYMRKGADALSKwVGEAERQLRLLFEEARKTQPSIIFFDEIDGLapvrsskqeqihASIVSTLLALMDg 686
                 56789999***********98886666667777665555544233445566777777555699********9998888888888877777777788875 PP

      AAA_14  89 .egknldvivtGSnskl 104
                  +g +++viv G  +  
  EEA22244.1 687 mDG-RGQVIVIGATNRP 702
                 444.7788888876655 PP

>> TIP49  TIP49 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   5.5e-05     0.041      49      96 ..     584     634 ..     539     648 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 5.5e-05
                 XXXXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXXX CS
       TIP49  49 aGravLlaGpsgtGktalaiaiskelg...edvpfvalsgsevyslevkkt 96 
                   r+vL+ Gp+gtGkt +a a++ +++   ++v f + +g++  s  v  +
  EEA22244.1 584 PPRGVLFHGPPGTGKTLMARALASSVSsegRKVTFYMRKGADALSKWVGEA 634
                 469****************99999997444789999988888877766555 PP

>> Zot  Zonular occludens toxin (Zot)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.018        14       4      52 ..     589     635 ..     587     683 .. 0.68
   2 ?    5.5   0.1     0.016        12      40      99 ..    1522    1578 ..    1495    1593 .. 0.75

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.018
         Zot   4 lvtGapGsgKtsgavkkdllpalkegRkiitnidGlr.lerieqvlgekv 52 
                 l++G+pG+gKt+ a    +   + egRk+ + ++  +  +++ + +ge+ 
  EEA22244.1 589 LFHGPPGTGKTLMARAL-ASSVSSEGRKVTFYMR--KgADALSKWVGEAE 635
                 89**********99766.7778889999988776..33555555555444 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.016
         Zot   40 rlerieqvlgekvstarliridnpegaetlkefakwatidkgallviDEcqeifpvrake 99  
                  r e   +  g +v  ++l +i+ ++  +++k+   w++  k a+l+  E +e+f   +++
  EEA22244.1 1522 RTELTLRTSGCTV--EQLEQINTHLMDCLWKKRGEWDR-TKVAVLLQEEFNEVFQDMQQN 1578
                  4444444444444..479999999**************.89*************988775 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00017      0.13      25      44 ..     588     607 ..     585     622 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00017
  Mg_chelatase  25 lllvGppGsGKtmlakrlps 44 
                   +l+ GppG+GKt++a++l+s
    EEA22244.1 588 VLFHGPPGTGKTLMARALAS 607
                   799*************9986 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   0.00019      0.14       2      21 ..     588     607 ..     588     675 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00019
      AAA_33   2 vllvGlpGsGKstlaerllk 21 
                 vl++G+pG+GK+  a+ l+ 
  EEA22244.1 588 VLFHGPPGTGKTLMARALAS 607
                 79**************9975 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   0.00024      0.18      36      63 ..     588     615 ..     580     674 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00024
      RuvB_N  36 vllyGpPGlGkttlakiiakelgvklki 63 
                 vl++GpPG Gkt +a+ +a+ + ++ + 
  EEA22244.1 588 VLFHGPPGTGKTLMARALASSVSSEGRK 615
                 9******************998776554 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   0.0    0.0031       2.4      24      49 ..     587     612 ..     577     631 .. 0.79
   2 ?   -1.8   0.0       2.9   2.2e+03      93     117 ..     649     676 ..     632     723 .. 0.61
   3 ?    0.7   0.0       0.5   3.7e+02      10      43 ..     876     909 ..     869     922 .. 0.75

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0031
                      -EEEECSTTSSHHHHHHHHHHHSTTT CS
  Sigma54_activat  24 svlitGesGtGKellaraiheaskrk 49 
                       vl +G  GtGK+l+ara+ ++ + +
       EEA22244.1 587 GVLFHGPPGTGKTLMARALASSVSSE 612
                      599***************98754433 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 2.9
                      TTSEEEEETGGGS-H...HHHHHHHHHH CS
  Sigma54_activat  93 dgGtlfLDeigelpl...elQekLlrvl 117
                      + +++f+Dei  l +   + Qe++   +
       EEA22244.1 649 QPSIIFFDEIDGLAPvrsSKQEQIHASI 676
                      4568999999877641114455554444 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 0.5
                      HHHHHHHHHCTSSS-EEEECSTTSSHHHHHHHHH CS
  Sigma54_activat  10 elleqikkvaktdlsvlitGesGtGKellaraih 43 
                      ++l++ ++    + ++li+G +G G ++la a+ 
       EEA22244.1 876 QMLQEFETSRIFRPRLLIRGLQGMGQQYLAGAVL 909
                      5555666666666789**************8863 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   0.00031      0.23      34      62 ..     586     614 ..     575     657 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00031
       AAA_7  34 kpvllvGptGtGKtviikdllkkldkeky 62 
                 + vl+ Gp GtGKt++++ l +++++e  
  EEA22244.1 586 RGVLFHGPPGTGKTLMARALASSVSSEGR 614
                 679****************9999986654 PP

>> AAA_3  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00036      0.27       2      32 ..     588     618 ..     587     663 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00036
       AAA_3   2 vllegvPGlaktllvkalakaldlefkriqf 32 
                 vl++g PG++ktl+++ala++++ e +++ f
  EEA22244.1 588 VLFHGPPGTGKTLMARALASSVSSEGRKVTF 618
                 7899*******************99999987 PP

>> TrwB_AAD_bind  Type IV secretion-system coupling protein DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.2     0.012       8.8     287     361 ..     173     245 ..     167     248 .. 0.89
   2 ?    3.5   0.0     0.037        27      17      53 ..     587     623 ..     584     636 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.012
  TrwB_AAD_bind 287 evYGedaaqsilslvntklilrvsdaetAeelsell.GeqeversteslsygannsrdgvslgrqrevrpvVlase 361
                    ++Y   ++   +++++  +++++++ ++  ++s+++ G   +e+++e+   g+nn+r++  + ++++++  Vl+s+
     EEA22244.1 173 DIYALTNSGRHVETIEEGVVAAAQAPRSTRRASKTVaGATPIEEEDEN---GSNNVRSIDESAETKQSQLEVLESD 245
                    6788888888899999999999998888888888888***********...77****************9999986 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.037
  TrwB_AAD_bind  17 hilivGttGsGKtqalekllrairargdraivlDltG 53 
                     +l+ G  G+GKt ++++l  ++ + g ++  +  +G
     EEA22244.1 587 GVLFHGPPGTGKTLMARALASSVSSEGRKVTFYMRKG 623
                    67899******************99999887766666 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00042      0.32      20      42 ..     588     610 ..     579     647 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00042
      AAA_11  20 tliqGPPGtgKTktivellsqll 42 
                 +l++GPPGtgKT +  +l s++ 
  EEA22244.1 588 VLFHGPPGTGKTLMARALASSVS 610
                 699*********99999998884 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1603 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1476  (0.0823247); expected 358.6 (0.02)
Passed bias filter:                      623  (0.0347482); expected 358.6 (0.02)
Passed Vit filter:                       138  (0.00769703); expected 17.9 (0.001)
Passed Fwd filter:                        59  (0.00329076); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              24  [number of targets reported over threshold]
# CPU time: 1.62u 0.35s 00:00:01.97 Elapsed: 00:00:00.54
# Mc/sec: 8968.13
//
Query:       EEA22245.1  [L=119]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (119 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       618  (0.0344693); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.25s 00:00:00.63 Elapsed: 00:00:00.41
# Mc/sec: 869.97
//
Query:       EEA22246.1  [L=1383]
Description: cleavage and polyadenylation specificity factor subunit A, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.3e-105  353.3   0.0     6e-104  347.8   0.0    2.5  3  CPSF_A    CPSF A subunit region
    9.5e-20   70.7   0.0    1.6e-19   69.9   0.0    1.3  1  MMS1_N    Mono-functional DNA-alkylating methyl methanesulfon


Domain annotation for each model (and alignments):
>> CPSF_A  CPSF A subunit region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    2.6   0.0    0.0079        70      32      99 ..      19      87 ..      11     113 .. 0.82
   2 ?   -3.7   0.0      0.62   5.6e+03      97     132 ..     308     342 ..     302     347 .. 0.82
   3 !  347.8   0.0  6.7e-108    6e-104       3     322 .]    1009    1348 ..    1007    1348 .. 0.96

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.0079
                --B-SSTTT---B--EEEEEEE---SSS--E.EEEEEEEEEE-.....SS--EEEEEEEEEEEES----EEEE CS
      CPSF_A 32 velessettkekkellvVGtafnlgedpaarsGrilvfeiiev.....petnrkLklvhkeevkgavtalaef 99
                + ++s     + k+l+vV t++++   + a+++  l++e +++     +++  kL+l ++ ++ g+vt ++++
  EEA22246.1 19 AAFTSA----TAKNLIVVKTSLLQIYTLVAETSTTLILENDQQadddvKNEATKLHLHAEYDLYGTVTDISPV 87
                555533....358899999999999998888899999999999999998888999999999999999998877 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 0.62
                 EEETTEEEEE-SSEEEEEEE-TTS-EEEEEEEE-SS CS
      CPSF_A  97 aefqGrllvgvgqkvrvydlgedktLlrkafldtql 132
                 a++ G ll+g ++++ + + g+ +  +++ ++ +q+
  EEA22246.1 308 APVGGTLLIGSNEMIHIDQSGKAS-AVAVNEFAKQV 342
                 57899************9999999.77777766665 PP

  == domain 3  score: 347.8 bits;  conditional E-value: 6.7e-108
                  EEEEE-T..TT-EEEEE--TTEEEEEEEE--B-SSTTT---B--EEEEEEE---SSS--E.EEEEEEEEEE-......SS--EEEEEEEEEEEES-- CS
      CPSF_A    3 siklvdpiskeeidsleLeenEavlsvksvelessettkekkellvVGtafnlgedpaarsGrilvfeiiev......petnrkLklvhkeevkgav 93  
                  sikl++p+++++ids+ +++ E++++v++++le se+t+++k+++vVGt++ +ged+aar G+++vf++i+v      p tn kLkl+ +e ++gav
  EEA22246.1 1009 SIKLINPKTWKVIDSYTFSPAERITAVENINLEISEKTGKRKDMIVVGTTYAKGEDIAAR-GNVYVFDVIDVvpdpdePGTNLKLKLIGEESIRGAV 1104
                  89**********************************************************.*****************999**************** PP

                  --EEEE..TTEEEEE-SSEEEEEEE-TTS-EEEEEEEE-SS-EEEEEEETT..EEEEEESSS-EEEEEE-SSS--EEEEEEESS---EEEEEEE--S CS
      CPSF_A   94 talaef..qGrllvgvgqkvrvydlgedktLlrkafldtqlyvvslkvlgn..riivgDlmkSvtfveydeenyklilfardtqkrwvtaaeflvdg 186 
                  ta++++  qG+++v++gqk++v++l++d++Ll++af+d+q+yv+ +k+l++  ++++gD++k+++f +y+ee+yk++lf++d+  ++v++a+fl+dg
  EEA22246.1 1105 TAVSGIggQGFMIVAQGQKCMVRGLKDDGSLLPVAFIDVQCYVSVIKELKGtgMCLIGDAFKGLWFTGYSEEPYKMTLFGKDLDELEVVTADFLPDG 1201
                  ******99999**************************************8888******************************************** PP

                  SS.EEEEEETTSEEEEEE--TTSGGGTTTT.EEEEEEEEE-SS----E...EEEE..SSS--S................-EEEEEE-TTS-EEEEEE CS
      CPSF_A  187 ed.tvlvaDkfgnlfvlrydpeasessdgdprleeraefhlgeivtslrkgslvp.geaesss................spqllyatldGsigllvP 265 
                  ++ ++lvaD ++nl vl+ydpe+++ss+gd rl++r++fh+g+++++l   +l+p ++ +s                   +q+l++t++Gs  l+++
  EEA22246.1 1202 KKlYILVADGDCNLYVLQYDPEDPKSSNGD-RLLNRCKFHMGHFASTL---TLLPrTAVSS-ElavmssdsmdidsytpLYQALITTQSGSMALITS 1293
                  ******************************.*****************...****633333.257899*************************9999 PP

                  .--HHHHHHHHHHHHHHHHHS--SSS--HHHHS---..----...---EEHHHHHHHHH CS
      CPSF_A  266 liseeeyrrlqaLqqqLrkelkhlgGldhrafRsyyspksee..vkgviDgdllerfld 322 
                   +see+yrrl+aLq+qL+++l+h++Gl++ra+Rs++s+       +g+iDg+ll r+ld
  EEA22246.1 1294 -LSEESYRRLTALQSQLSNTLEHPCGLNPRAYRSVESD---GvvGRGMIDGKLLMRWLD 1348
                  .**********************************985...245*************96 PP

>> MMS1_N  Mono-functional DNA-alkylating methyl methanesulfonate N-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.9   0.0   1.8e-23   1.6e-19       1     469 [.      97     708 ..      97     725 .. 0.73

  Alignments for each domain:
  == domain 1  score: 69.9 bits;  conditional E-value: 1.8e-23
      MMS1_N   1 DlLvvgsdsgelvflsynpeknqfetvhshe.......tlgksgsrrsqpGqylavDPkgraiavsayekvflvyslkk.................... 72 
                 D L+++    +l+++++npe++ + t+   +       tl++ + ++sq+  +l+vDP++r+  +    + + + ++++                    
  EEA22246.1  97 DALLLSFRNAKLSLIEWNPETQGISTMSI-HyyekediTLSPWVPDLSQCDSHLTVDPSSRCALLNFGVRNIAILPFHQagddlvmdeydpdldmddlt 194
                 6788899999************5555552.22459999*****************************************99987777776666654444 PP

      MMS1_N  73 keilnr.........ealllssplea...........rksegvilsmvFldpgykeednpi.ialleqdrrg..................kteltlyew 132
                      +                   +             +  ++l +++ldp+     +pi +++l++ r+                   ++++++y++
  EEA22246.1 195 D----QeenkkpshtD---------SkkaegdlihqtPYAASFVLPLTALDPTLI---HPIgLTFLHEYREPtfgilyspiatsaalleeRKDVVVYSV 277
                 1....13333333331.........123334455446677888888888888885...44424444433333334444444444445555556666665 PP

      MMS1_N 133 dlglnlvrkisktsepkk..nldsganlLiplpkp.gg.vlVcgetiitykdildqedirkk.......swarPrrekatn...............fva 205
                  ++l+l ++ s++ +  +  +l+s   ++++lp p gg +l+ ++++i ++++++++++ ++       +   P                      ++ 
  EEA22246.1 278 -FTLDLEQRASTPLL--SiaKLPSDLLHIMALPAPvGGtLLIGSNEMIHIDQSGKASAVAVNefakqvsA--FPM-----VdqsdlelrlegsvveVIN 366
                 .33555555444433..1235777777*******8544799*9999****99988777555546665330..333.....1333456666665333334 PP

      MMS1_N 206 wekldsfffllatedGdLylleiekdedsgkvvtsislkyf.......dtvsvasalvilksgfLfvasefGdgqlyqieargedd............. 284
                 +e+    ++ll    G+L l+ ++   d g++v++  ++ +           vas+ v l+sg +f++se  ++ l+     +                
  EEA22246.1 367 NES---GDILLTLSTGELVLVHFKI--D-GRSVSGFVVFPIpavsggdVVSAVASCAVALGSGKVFIGSEDAESVLLDCYLPSAVSkksrdydrdhfde 459
                 444...56999999*********44..3.4779999999999999985445699********************5554433322113457788888889 PP

      MMS1_N 285 ....................................knleliqtldNlaPilDfkvv....kes....dlasegqdqiytcsGagkrgsLrelRsGiev 339
                                                       +++i++l +l+P+  ++v     ++s     ++s +  ++ ++ G+g+ g +  l+  + +
  EEA22246.1 460 emnneedddmyeddlyssapkeavnktvsngrisdnYTFKVIDRLLSLGPLRAVAVGkpasRDSnaedAQQSVDDLELAAAYGSGRGGGVALLQRTLHL 558
                 99********************************99899***************9999877333566333455558889999***************** PP

      MMS1_N 340 eelavseepgspitgvWtlklssede........yddylvlSfvne.....Tlvlsidgdgeveevtedsgllls.vpTLaagnlg.dgslvQVtpngi 423
                  ++ +++ + s +  vW + +s++++        +++y++l+  n+     Tlv  +  +++ e ++     + +  pT+ +++l+ + ++vQV +  +
  EEA22246.1 559 DDVFTLGAE-S-ADSVWNITTSNTKSghndsgeeNQSYVILTKANSpeneeTLVYAV-NERNLEPFN-APDVNPNgDPTIDIDVLAgNSRVVQVLTGEV 653
                 ****98777.4.59******9777666777888666******998888888******.556999999.5555554389*******95677********* PP

      MMS1_N 424 rliradk....rvs.ewkppng..ksiiaaaangeqllvalsgrelvyfeld...l 469
                 r+++++     +    w+ ++g  +  ++a++ ++ ll++ + ++++ ++ d   +
  EEA22246.1 654 RIYDTNLgmaqI-YpVWDEDEGdeRFAVSASFADHYLLIIRDDSSVLLLHSDesgD 708
                 ******999954.4489999974447888888999999999999999987753442 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1383 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       320  (0.0178482); expected 358.6 (0.02)
Passed bias filter:                      286  (0.0159518); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.84u 0.33s 00:00:01.17 Elapsed: 00:00:00.50
# Mc/sec: 8298.70
//
Query:       EEA22247.1  [L=577]
Description: LMBR1 domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.3e-18   66.4  22.1    1.9e-15   56.8  20.8    2.6  2  LMBR1            LMBR1-like membrane protein
     0.0094   16.1   7.2        1.2    9.3   0.1    4.1  3  DUF2964          Protein of unknown function (DUF2964)
  ------ inclusion threshold ------
       0.03   13.9   0.0      0.048   13.3   0.0    1.2  1  Anemone_cytotox  Sea anemone cytotoxic protein
        8.1    6.7  10.9        4.8    7.4   0.1    3.9  3  Pox_A14          Poxvirus virion envelope protein A14


Domain annotation for each model (and alignments):
>> LMBR1  LMBR1-like membrane protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.8  20.8   4.2e-19   1.9e-15       4     459 ..      11     433 ..       8     446 .. 0.70
   2 ?   -1.7   0.0      0.22     1e+03     128     152 ..     513     537 ..     505     556 .. 0.79

  Alignments for each domain:
  == domain 1  score: 56.8 bits;  conditional E-value: 4.2e-19
       LMBR1   4 iillllflllfllallllrrykrkkdqeavvkllvllalalsflivlllPlDiastiyrq..........nealypcsyylqwlsesl..ikvlWrivY 90 
                 i+ ++++ +l+ +a+++++ y++++d++ +v++++ +++   +++vll P+D+a  + +           +            +++ +  ++v++ ++Y
  EEA22247.1  11 IVYAIVVAILLAVASIFIYIYQTPRDRSPFVTIVSIITITALLATVLLQPVDVALVSSTTssklgrrkdwA--------SQDEVDKIVfsLRVVYYLLY 101
                 788999999*********************************************95444444444433221........22234444445899****** PP

       LMBR1  91 wlsnlllwiilPfaqfYvesggftgkgkl.krslyenaiiyllllvivlglliyvliil...................qklsllsik.sllpilislan 168
                  l+ +l+ +++Pf++f +e  +    + + +++  +  ++++ +   +  +++ v++ l                   +kl + +     l+++  +  
  EEA22247.1 102 SLDAVLCLLVVPFTYFWYEEYDEIAVQEGeQTA-GK--RFWGAFKYTIAFVVLAVFLFLagffipikgisedkdldffKKLLTENHGeRALTFALGILL 197
                 ****************88877777767785444.33..3333333333333333333223356889************7777888888*********** PP

       LMBR1 169 twGlvllilllGyGlvelPrslwreiksdldeelkklyfeaaklntekeeaereledllkevkklrksisesdplrkyleeilkkvPeeiaeklksnen 267
                 t+G++l ++ + +G++ lP++l+++  s ++ +lk+    a++l+ +  e +r+l+          +   + d                          
  EEA22247.1 198 TLGTILYVVYTSVGFAFLPITLIKTAPSISNPTLKAN--TASQLD-SNRERQRQLN---------ARCGGDPD-------------------------- 258
                 ************************5555556666666..555555.3333456666.........22223333.......................... PP

       LMBR1 268 kteeslaklekqlikalqkrertekqwkrllekalelediiknksskekefksses.srrgefakqgklkltptleyywaklllplvllilsiilvlls 365
                     +l++  ++    l ++ert  + +rl+e+a                     + + r+++++   ++ t  +  + + l    +ll+l +ilv  s
  EEA22247.1 259 ----QLSSKDRRELDGLVREERTLIRRQRLIEQA---------------------QgEGRSWLIRA--WFKTEAVFRPFKLLGG--ILLLLVAILVWVS 328
                 ....899999999999999999999999999999.....................33445555544..4445555555553333..3333333333333 PP

       LMBR1 366 iiiilseltklle..................kppls.lfalfievsaessfglfga.elieillilYlmlcayvglfklkl.pnfyrlap..hhqTdms 441
                 ++ +                            ++++ ++ +f+     +s ++f +  ++++l++l +  +++vg+ ++++ +  +r+ +  +++T+ +
  EEA22247.1 329 MLLTA-------VdkaknsvckhncgyilghINVFNpINWIFV-----RSAQVFPVdYVLFALVVLLFFSSSVVGIATVGIrFLWIRIFRirKGHTSPQ 415
                 33333.......1222224467888888764333443444444.....444444443378888888889999*********988888888888****** PP

       LMBR1 442 slifnaalllrltsPlcl 459
                  l++ +++l ++t +l +
  EEA22247.1 416 ALLIATVMLTLITLALNY 433
                 ************998765 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.22
       LMBR1 128 iiyllllvivlglliyvliilqkls 152
                 i+++ +++++l l+i+v +++   +
  EEA22247.1 513 IFWAQFAFLGLYLIILVTTLFRTPK 537
                 7888899999999999998874444 PP

>> DUF2964  Protein of unknown function (DUF2964)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.3     0.011        48      40      62 .]      15      37 ..       9      37 .. 0.85
   2 !    9.3   0.1   0.00028       1.2       6      33 ..     144     171 ..     142     179 .. 0.85
   3 ?    3.7   0.2     0.016        72      37      56 ..     312     331 ..     303     336 .. 0.87

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.011
     DUF2964 40 gvialliGiaafVvlLnpaprDe 62
                 v+a+l+ +a++ +    +prD+
  EEA22247.1 15 IVVAILLAVASIFIYIYQTPRDR 37
                3789****************995 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.00028
     DUF2964   6 lRvvlAtiavFiaLagiaaaihGlLfde 33 
                 + +++  +avF+ Lag +  i+G+  d+
  EEA22247.1 144 YTIAFVVLAVFLFLAGFFIPIKGISEDK 171
                 6689999***************986665 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.016
     DUF2964  37 lrygvialliGiaafVvlLn 56 
                 l +g+++ll+ i+  V++L 
  EEA22247.1 312 LLGGILLLLVAILVWVSMLL 331
                 678**************995 PP

>> Anemone_cytotox  Sea anemone cytotoxic protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   1.1e-05     0.048      86     136 ..      94     144 ..      46     149 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.1e-05
                      EEEEEEETTTEEEEEEEEE-SSTTTS--EEEEEEESSSS--SHHHHHHHHC CS
  Anemone_cytotox  86 gvlaykmsdgntlavlfsvpfdynlysnwwnvkiykgkrradqkmyeelyy 136
                       v+ y++ + +++  l+ vpf y +y ++ ++ + +g++ a ++++  + y
       EEA22247.1  94 RVVYYLLYSLDAVLCLLVVPFTYFWYEEYDEIAVQEGEQTAGKRFWGAFKY 144
                      56778888888999999************************9999876655 PP

>> Pox_A14  Poxvirus virion envelope protein A14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   3.0      0.13   5.7e+02      17      58 ..      16      51 ..       4      72 .. 0.59
   2 ?    7.4   0.1    0.0011       4.8      50      69 ..     189     208 ..     173     212 .. 0.86
   3 ?    0.6   0.1      0.14   6.4e+02      15      28 ..     312     325 ..     307     357 .. 0.68

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.13
     Pox_A14 17 aGiiLLilacifafvdfskststtdkawralsivsFilgivi 58
                +  iLL++a if ++          +++ +  ivs i++i +
  EEA22247.1 16 VVAILLAVASIFIYIYQTPRDR---SPFVT--IVS-IITITA 51
                3457999999999996443333...22222..222.122222 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0011
     Pox_A14  50 vsFilgivillglllfsmyg 69 
                 ++F lgi+++lg++l+ +y 
  EEA22247.1 189 LTFALGILLTLGTILYVVYT 208
                 68**************9995 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.14
     Pox_A14  15 liaGiiLLilacif 28 
                 l+ Gi+LL +a+++
  EEA22247.1 312 LLGGILLLLVAILV 325
                 56788888888753 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (577 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1133  (0.0631937); expected 358.6 (0.02)
Passed bias filter:                      482  (0.0268838); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                        18  (0.00100396); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.78u 0.35s 00:00:01.12 Elapsed: 00:00:00.52
# Mc/sec: 3311.49
//
Query:       EEA22248.1  [L=305]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        0.3   10.7   2.9       0.39   10.3   2.9    1.3  1  GET2      GET complex subunit GET2
       0.76   10.1   9.2        1.3    9.3   9.2    1.3  1  CEBP_ZZ   Cytoplasmic polyadenylation element-binding protein


Domain annotation for each model (and alignments):
>> GET2  GET complex subunit GET2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   2.9   4.4e-05      0.39      48     161 ..     103     212 ..      32     234 .. 0.66

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 4.4e-05
        GET2  48 epaaekttpasttasssssasehddp..eiediseiavkpkktasskkksplseesepeapqldqllkqllqqqqqgnsensqdaesstPdlfsqllkm 144
                 +++a+++   +t +++s++++  +d    i++ s   + p+ +    + s+++ + + ++ ++ ++lk++++++++ ++++++++e   ++ +++llk+
  EEA22248.1 103 SETAATQIGDKTGNDESQTRELLSDAygFIQQASGTEPDPSIN----SPSHVNFK-KGKEDDIPDFLKDIDSSNEEDDESDEEKEEAEAAKYVENLLKE 196
                 2333334444444444444443333334444444444444322....22333333.34445999999****9998888888888888788999999999 PP

        GET2 145 mkqgeggsakseeetss 161
                  +++    a+  e++s+
  EEA22248.1 197 IAENPPP-ASPIEDSST 212
                 9998877.222222222 PP

>> CEBP_ZZ  Cytoplasmic polyadenylation element-binding protein ZZ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   9.2   0.00014       1.3      12      58 ..     256     299 ..     252     301 .. 0.88

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00014
     CEBP_ZZ  12 seCeiCekakargpyfCrdlaCfkYyCetCwqrrHsaeskeaaHrpl 58 
                 s+C iC  ++   +  C d +  + +C  Cw ++H  ++ ++ H+ +
  EEA22248.1 256 SCCCICYDTA---KLKCMDCEGDQLFCVRCWWEMHLDDEGDSGHKAV 299
                 4789998865...9*********************999999999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (305 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1183  (0.0659825); expected 358.6 (0.02)
Passed bias filter:                      637  (0.035529); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 2028.78
//
Query:       EEA22249.1  [L=117]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
       0.23   11.1   2.8       0.52   10.0   0.6    1.9  2  Tubulin_3  Tubulin domain


Domain annotation for each model (and alignments):
>> Tubulin_3  Tubulin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.6   2.9e-05      0.52      30      68 ..      17      55 ..       8      68 .. 0.76
   2 ?    2.0   0.2    0.0081   1.5e+02     108     149 ..      63     105 ..      57     113 .. 0.69

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 2.9e-05
   Tubulin_3 30 eyelnskllpfedwsvGeeLfeeldkehdlldrdlrpfa 68
                +  l+ + l+   w+   e+f++  keh+ ldrdl+   
  EEA22249.1 17 DLSLQPEDLQKCSWDQLLEMFSSALKEHEQLDRDLQHQT 55
                556666666666699999****************98754 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.0081
   Tubulin_3 108 lvWvlaleeklkkkkkaklerklkkl.nkarslkelseqasly 149
                  +W+  + +  ++++ ++++ +++++ n+ r l+e +e+ +++
  EEA22249.1  63 EIWTQVTVSRDEDRSYKRFQTRMQHVqNSERELEEKKEHYANV 105
                 4787766666666666777777777659999988877665554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (117 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1719  (0.0958782); expected 358.6 (0.02)
Passed bias filter:                      562  (0.0313459); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.38
# Mc/sec: 911.88
//
Query:       EEA22250.1  [L=293]
Description: ribosome recycling factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.4e-43  146.1   1.7    1.5e-42  145.3   1.7    1.4  1  RRF              Ribosome recycling factor
  ------ inclusion threshold ------
       0.16   11.6   5.6        4.1    7.0   1.4    2.1  2  DUF4813          Domain of unknown function (DUF4813)
       0.16   12.1   2.3        4.5    7.4   0.3    2.4  2  Cob_adeno_trans  Cobalamin adenosyltransferase
       0.18   11.9   3.1       0.15   12.1   1.2    1.7  2  DUF4778          Domain of unknown function (DUF4778)
       0.37   11.3   3.8        2.3    8.8   0.6    3.0  3  HisKA_3          Histidine kinase
        1.6    9.4  10.7        3.8    8.2   3.1    3.0  3  KfrA_N           Plasmid replication region DNA-binding N-ter
        4.1    8.0   9.9    1.2e+02    3.4   9.6    3.0  2  YtxH             YtxH-like protein
        5.3    7.1   7.4        1.8    8.6   2.8    2.4  3  DUF1664          Protein of unknown function (DUF1664)
        7.1    7.6   7.3         19    6.2   1.6    2.3  2  Gastrin          Gastrin/cholecystokinin family
        7.3    6.9   9.2         72    3.7   5.0    3.6  3  WXG100           Proteins of 100 residues with WXG
        9.1    6.7  10.9        2.7    8.4   0.8    2.5  2  DUF1690          Protein of Unknown function (DUF1690)


Domain annotation for each model (and alignments):
>> RRF  Ribosome recycling factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.3   1.7   9.3e-46   1.5e-42       1     159 [.     119     288 ..     119     290 .. 0.92

  Alignments for each domain:
  == domain 1  score: 145.3 bits;  conditional E-value: 9.3e-46
                 HHHHHHHSS-S...SSSCGGGTTSEEEETTE...EEEGGGTEEEEESSTTEEEEEESSCCHHHHHHHHHHHSCC-SEEEEESS...EEEEE--SSSHHH CS
         RRF   1 lkkelsklrtg...ranpslldnikVeyygk...ktpLnqlAqvsvkeartllitpfdkslvkaiekaIlksdlglnpqqdge...vlrvpipplTeEr 90 
                 +k++l+klr+g   r+np+++++++V   +    +++L+++Aqv++k++r + i   +++l+k++ +aI++s l+l+pq d +   +l+vpipp+T+E+
  EEA22250.1 119 FKEDLQKLRSGgggRLNPEVIEQLRVHIVKGsneTVRLSEVAQVVPKGGRAVAIIIGEEDLIKPVNSAIISSSLSLTPQPDAHnplQLNVPIPPPTKES 217
                 799******94456************74444466799*****************************************97766789************* PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.CS-H.HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
         RRF  91 rkelvkeakkaaekakvairniRrdankklkklek.kise.Ddvkkaekeiqkltdkyikeidellkakek 159
                 r++ vk ak a++ka  a+r++R++++kkl++++k k ++ Dd++ka+++++kl++k +k++++ +++++k
  EEA22250.1 218 RDQAVKAAKGAMDKAASAVRSARAAIHKKLQDMQKrKEARpDDIRKAHDQMEKLVEKAQKDVKDTFESARK 288
                 ***********************************875556***************************998 PP

>> DUF4813  Domain of unknown function (DUF4813)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   1.4    0.0025       4.1     116     133 ..      84     101 ..      73     104 .. 0.86
   2 ?    6.8   0.2    0.0029       4.8     131     235 ..     138     241 ..     108     258 .. 0.64

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0025
     DUF4813 116 ehapsssgggggggggge 133
                 e +p+ +gggggggg+++
  EEA22250.1  84 ESSPATTGGGGGGGGAAD 101
                 789999999999998765 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.0029
     DUF4813 131 ggedkiiiinngppgsvttsevgsgttvinaggqqqaa..paapaaaaapaaaaaqvpaaapapvaaapqtplaplapvaalaaaaagaaaapvdvaaa 227
                   e+  + i  g   +v  sev   + v+  gg   a     +   +   +a  ++  + +p p a +p+    p+ p + ++   a++aa ++  +aa
  EEA22250.1 138 VIEQLRVHIVKGSNETVRLSEV---AQVVPKGGRAVAIiiGEEDLIKPVNSAIISSSLSLTPQPDAHNPLQLNVPIPPPTKESRDQAVKAAKGAMDKAA 233
                 2333334455555555555554...57888888887763333444455555666777788999999999998899999988888888888888755555 PP

     DUF4813 228 apaaaapp 235
                 +   +a +
  EEA22250.1 234 SAVRSARA 241
                 55554444 PP

>> Cob_adeno_trans  Cobalamin adenosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.1     0.022        36      49      81 ..      43      78 ..      14     163 .. 0.79
   2 ?    7.4   0.3    0.0027       4.5      21      63 ..     218     278 ..     214     292 .. 0.67

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.022
                     T.....THHHHHHHHHHHHHHHHHHHHHHT.-BTCCG- CS
  Cob_adeno_trans 49 e.....eeelkeaLeeiqneLfdlgaelatpekkkekk 81
                     +     + +++++L+++q++ f+  a l+ ++   ++k
       EEA22250.1 43 QtsssiTPRIQKTLTQLQRHTFTTSAVLSKKK--DKSK 78
                     23445567899999999999999999998552..2222 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0027
                      TTHHHHHHHHHHHHHHHHHHHHHHHCTTT..................THHHHHHHHHHHHH CS
  Cob_adeno_trans  21 KddprveayGtvDelnsaiglarallaee..................eeelkeaLeeiqne 63 
                      +d+++  a G++D++ sa+  ara ++++                  ++++++ +e+ q++
       EEA22250.1 218 RDQAVKAAKGAMDKAASAVRSARAAIHKKlqdmqkrkearpddirkaHDQMEKLVEKAQKD 278
                      677778899**************88876666666665555555555444444444445544 PP

>> DUF4778  Domain of unknown function (DUF4778)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.62     1e+03     135     190 ..      52      79 ..      12     166 .. 0.61
   2 ?   12.1   1.2   9.1e-05      0.15      98     194 ..     194     289 ..     174     293 .] 0.85

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.62
     DUF4778 135 ierrlklakragigsesaarqngkRrrkelkekedeekselneiaelldgqdaaer 190
                 i+++l+  +r     +++                            l +++d+++r
  EEA22250.1  52 IQKTLTQLQRHTFTTSAV----------------------------LSKKKDKSKR 79 
                 333333333333333333............................2222222222 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 9.1e-05
     DUF4778  98 LkgqkesdnaahkklfgneslrkreraskkrekgqrkierrlklakragigsesaarqngkRrrkelkekedeekselneiaelldgqdaaervkke 194
                 L  q++++n+ + + +  + +++ + +  k  kg +    ++++  ra i ++   +q+ k  r+   +k++++ ++l  ++++ d +d+ e   k 
  EEA22250.1 194 LTPQPDAHNPLQLNVPIPPPTKESRDQAVKAAKGAMDKAASAVRSARAAIHKKLQDMQKRKEARPDDIRKAHDQMEKL-VEKAQKDVKDTFESARKG 289
                 445688889999999999999999999999999*99999********************9999988888888888887.777888888877766655 PP

>> HisKA_3  Histidine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.0       1.8   2.9e+03      44      65 ..     107     128 ..     104     130 .. 0.75
   2 ?    2.6   0.4      0.12     2e+02      36      61 ..     219     244 ..     212     251 .. 0.58
   3 ?    8.8   0.6    0.0014       2.3      20      64 ..     243     287 ..     241     291 .. 0.85

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 1.8
                 HHHHHHHHHHHHHHHHHHHHTT CS
     HisKA_3  44 eieelarealqevRrllhnLrp 65 
                 ++++ +++al+  ++ l++Lr+
  EEA22250.1 107 QLQTGISDALTRFKEDLQKLRS 128
                 6778888888888888888875 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.12
                 HHHHHHHHHHHHHHHHHHHHHHHHHH CS
     HisKA_3  36 ekaaeqlreieelarealqevRrllh 61 
                 ++a ++++ + + a +a++ +R+++h
  EEA22250.1 219 DQAVKAAKGAMDKAASAVRSARAAIH 244
                 45555555566666666666666555 PP

  == domain 3  score: 8.8 bits;  conditional E-value: 0.0014
                 HHHHHHHHHHHTTT-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHT CS
     HisKA_3  20 iklqlelakrllekdpekaaeqlreieelarealqevRrllhnLr 64 
                 i  +l+ ++++ e++p++++++ +++e+l+++a+++v+++ +  r
  EEA22250.1 243 IHKKLQDMQKRKEARPDDIRKAHDQMEKLVEKAQKDVKDTFESAR 287
                 566778888888999**********************99877766 PP

>> KfrA_N  Plasmid replication region DNA-binding N-term
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0       1.6   2.7e+03      21      36 ..     139     154 ..     131     156 .. 0.90
   2 ?    8.2   3.1    0.0023       3.8      68     110 ..     214     256 ..     190     261 .. 0.83
   3 ?    5.9   0.4     0.012        20      58      92 ..     256     292 ..     252     293 .] 0.85

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 1.6
      KfrA_N  21 veavrerlGgGspnti 36 
                 +e++r ++ +Gs+ t+
  EEA22250.1 139 IEQLRVHIVKGSNETV 154
                 6899*********998 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.0023
      KfrA_N  68 laalwqaaleeaeeelaaaraelqaaraaleaeraeaearvee 110
                 +++  ++a+++a+ ++++a +++++araa+ ++++++++r e+
  EEA22250.1 214 TKESRDQAVKAAKGAMDKAASAVRSARAAIHKKLQDMQKRKEA 256
                 4666789******************************999886 PP

  == domain 3  score: 5.9 bits;  conditional E-value: 0.012
      KfrA_N  58 elPealaeal..laalwqaaleeaeeelaaaraelqa 92 
                 + P+++ +a   +++l ++a+++ +++ ++ar+ +++
  EEA22250.1 256 ARPDDIRKAHdqMEKLVEKAQKDVKDTFESARKGMEQ 292
                 5699999888888******************999887 PP

>> YtxH  YtxH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0      0.68   1.1e+03      25      44 ..     107     126 ..     106     155 .. 0.76
   2 ?    3.4   9.6     0.071   1.2e+02      24      69 ..     215     281 ..     211     293 .] 0.82

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.68
        YtxH  25 etRkdlkekaddlkekakel 44 
                 +++  +++++  +ke++++l
  EEA22250.1 107 QLQTGISDALTRFKEDLQKL 126
                 57788999999999999877 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.071
        YtxH  24 ketRkdlkekaddlkekakelleeakeka.....................kekaedlkekvkekade 69 
                 ke R++++++a+ + +ka +++ +a+                         ++ e+l+ek+++++++
  EEA22250.1 215 KESRDQAVKAAKGAMDKAASAVRSARAAIhkklqdmqkrkearpddirkaHDQMEKLVEKAQKDVKD 281
                 899**********************999999999999998888888777766666666666666655 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.1      0.84   1.4e+03      68      96 ..      35      63 ..       2      79 .. 0.62
   2 ?   -2.3   0.0       2.6   4.3e+03      83      98 ..     110     125 ..     105     129 .. 0.45
   3 ?    8.6   2.8    0.0011       1.8      35      98 ..     214     281 ..     213     292 .. 0.73

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.84
     DUF1664 68 idrvdkkldeqkeiskeikeevtevredl 96
                i++  ++ + ++ i+  i++ +t++++++
  EEA22250.1 35 INKTISQHQTSSSITPRIQKTLTQLQRHT 63
                55555555556666666666666666554 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 2.6
     DUF1664  83 keikeevtevredlse 98 
                 + i++ +t+ +edl++
  EEA22250.1 110 TGISDALTRFKEDLQK 125
                 3344444444444443 PP

  == domain 3  score: 8.6 bits;  conditional E-value: 0.0011
     DUF1664  35 TkrslsdavesvskqleqvseslaatkrhLssridrvdkkldeqke....iskeikeevtevredlse 98 
                 Tk s  +av+     +++  +++++++  + ++++ ++k+ ++  +    +  ++++ v+++++d+++
  EEA22250.1 214 TKESRDQAVKAAKGAMDKAASAVRSARAAIHKKLQDMQKRKEARPDdirkAHDQMEKLVEKAQKDVKD 281
                 8888899999999************************9988766550000455555555555555554 PP

>> Gastrin  Gastrin/cholecystokinin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.4     0.038        62      23      63 ..      43      85 ..      11      91 .. 0.66
   2 ?    6.2   1.6     0.012        19      22      91 ..     215     287 ..     201     293 .] 0.66

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.038
     Gastrin 23 ksseavleeaeesleeaqrha..raaasskqlkalqradeeed 63
                ++s++++ + +++l++ qrh+   +a+ sk+  + +r+d++e+
  EEA22250.1 43 QTSSSITPRIQKTLTQLQRHTftTSAVLSKKKDKSKRNDDAES 85
                2223677778888888999987555666666666666666544 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.012
     Gastrin  22 sksseavleeaeesle...eaqrharaaasskqlkalqrade.eedqranlseLLarllsqkkkgsvrrlsaak 91 
                 ++s++++++ a  +++   +a r ara a++k+l+ +q+++e   d  ++    + +l+++++k+   ++ +a+
  EEA22250.1 215 KESRDQAVKAAKGAMDkaaSAVRSARA-AIHKKLQDMQKRKEaRPDDIRKAHDQMEKLVEKAQKDVKDTFESAR 287
                 455554444444433322266677777.5577888887776636688888888899999999987776666655 PP

>> WXG100  Proteins of 100 residues with WXG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.1       2.3   3.7e+03      23      38 ..      45      60 ..      34      68 .. 0.54
   2 ?    1.4   0.0      0.23   3.7e+02      16      39 ..     105     128 ..     103     132 .. 0.78
   3 ?    3.7   5.0     0.044        72       5      36 ..     225     256 ..     221     293 .] 0.81

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 2.3
                HHHHHHHHHHHHHHCG CS
      WXG100 23 ledelqrlkaevdalq 38
                 +++  r+++++ +lq
  EEA22250.1 45 SSSITPRIQKTLTQLQ 60
                4444444444444442 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.23
                 HHHHHHHHHHHHHHHHHHHHHCGC CS
      WXG100  16 fqkqaeeledelqrlkaevdalqs 39 
                 f++ ++ ++d+l+r k ++++l+s
  EEA22250.1 105 FSQLQTGISDALTRFKEDLQKLRS 128
                 777788888888888888888865 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.044
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      WXG100   5 dpeelrqaaarfqkqaeeledelqrlkaevda 36 
                    ++++aa++++++++ ++  lq++++  +a
  EEA22250.1 225 AKGAMDKAASAVRSARAAIHKKLQDMQKRKEA 256
                 557899*******************9988765 PP

>> DUF1690  Protein of Unknown function (DUF1690)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   0.8    0.0016       2.7      27      72 ..      40      85 ..      31     128 .. 0.82
   2 ?    2.3   3.5      0.13   2.1e+02      75     113 ..     237     267 ..     214     291 .. 0.40

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0016
     DUF1690 27 raqalekliqerVaeeLkkLraeeeetlkkfeeklekellkdeada 72
                 ++++   i  r+++ L++L+++  +t + +++k +k++ +d+a++
  EEA22250.1 40 SQHQTSSSITPRIQKTLTQLQRHTFTTSAVLSKKKDKSKRNDDAES 85
                56778899************99999999999999999999988332 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.13
     DUF1690  75 elsskalnekieeLrkkleefkkkeeeklpeeveearee 113
                    ++a+++k+++++k+ e+         p+++++a ++
  EEA22250.1 237 RSARAAIHKKLQDMQKRKEAR--------PDDIRKAHDQ 267
                 223333444444444443332........2222222211 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (293 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1927  (0.10748); expected 358.6 (0.02)
Passed bias filter:                      858  (0.0478554); expected 358.6 (0.02)
Passed Vit filter:                       100  (0.00557756); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.42
# Mc/sec: 2100.89
//
Query:       EEA22251.1  [L=339]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (339 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       838  (0.0467399); expected 358.6 (0.02)
Passed bias filter:                      540  (0.0301188); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.23s 00:00:00.69 Elapsed: 00:00:00.38
# Mc/sec: 2660.08
//
Query:       EEA22252.1  [L=88]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.1e-18   67.8   0.1    1.3e-18   67.6   0.1    1.1  1  ANAPC_CDC26  Anaphase-promoting complex APC subunit CDC26
     0.0014   17.0   0.3     0.0014   17.0   0.3    1.0  1  Nop14        Nop14-like family


Domain annotation for each model (and alignments):
>> ANAPC_CDC26  Anaphase-promoting complex APC subunit CDC26
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.6   0.1   1.5e-22   1.3e-18       1      73 [.       1      72 [.       1      73 [. 0.96

  Alignments for each domain:
  == domain 1  score: 67.6 bits;  conditional E-value: 1.5e-22
  ANAPC_CDC26  1 MLRRkPTtItLtseDiaeyederqrqkeqaaqqqrsqasastsqasdtdaddftsedadpndelkssqtqdra 73
                 MLRRkPT+It+t+eD++++e+er+++ eq+a+++ +++  ++++a+++++ +++ +++dpndelk+++ +d+a
   EEA22252.1  1 MLRRKPTAITITPEDLIAFEEERLQKLEQEAANKLNAEGGGEGDARSESTLNTSGKKYDPNDELKPLP-GDKA 72
                 ************************************************999999*************9.8887 PP

>> Nop14  Nop14-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.3   1.5e-07    0.0014     262     318 ..       3      59 ..       2      85 .. 0.72

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 1.5e-07
       Nop14 262 RAkPsdRtKteEElakeekerLeklEeeRlkRMrge.....edeeeeeekkkkkkkeasaDd 318
                 R kP+  t t+E+l++ e+erL+klE+e  ++ + e     +  +e + ++++kk      d
  EEA22252.1   3 RRKPTAITITPEDLIAFEEERLQKLEQEAANKLNAEgggegDARSESTLNTSGKKY-----D 59 
                 6699999***************************9987664333333333333332.....2 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (88 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       479  (0.0267165); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.35u 0.27s 00:00:00.62 Elapsed: 00:00:00.40
# Mc/sec: 652.75
//
Query:       EEA22253.1  [L=457]
Description: hypothetical protein PMAA_060340 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.6e-51  175.0   0.1    3.8e-51  174.4   0.1    1.2  1  DDE_Tnp_1_7  Transposase IS4


Domain annotation for each model (and alignments):
>> DDE_Tnp_1_7  Transposase IS4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  174.4   0.1   2.1e-55   3.8e-51       2     310 ..      69     426 ..      68     447 .. 0.89

  Alignments for each domain:
  == domain 1  score: 174.4 bits;  conditional E-value: 2.1e-55
  DDE_Tnp_1_7   2 pvelFelflpdkilerivkatNayakqk.........kkwleltaeElkaFlGllllmglvrlpsvedyWstkdfyg....npllseiMsreRFeeil 86 
                  p+++F+lf+++++++ +++ tN+ya  k         ++w+ +t  ElkaF+G+++ mg  + p+++dyW+++++ +    n++ls +++  RFe++ 
   EEA22253.1  69 PYQIFSLFFTEDLFKVLADNTNMYAYAKlsknmnphhRNWRSTTPGELKAFVGAQIYMGFTKEPQLKDYWDEEKHNKsvhaNHPLSNYITCFRFEQLK 166
                  9**********************************************************************9995555678***************** PP

  DDE_Tnp_1_7  87 salhladn........................stkkaekdklkkvrelidslnermqkvyrpsqtlvldeslvlfkgrvpfkqylpgkprkvgiklhv 160
                  + +h++++                        s+++ +    +kv  ++d l +  +++y ps+++++de +v  +gr +    +p+kp   g+k++v
   EEA22253.1 167 RFFHISEPsevpggfistyyrpepteeeelqlSEEQLSGIWWHKVHTVFDILRKASKNLYIPSSNISIDEAMVCSHGRSSHTYKMPNKPISQGFKIFV 264
                  ***********************9999888664444488999******************************************************** PP

  DDE_Tnp_1_7 161 lcdsqtgyilalelyegearnlrl..srelgktnalvlrLleplqgkg..rvvvmdnfftslellqeLakkgtyavGtlkknrsglPkeltqklpkge 254
                  l+d   gy + +++  ++++ ++    +el+kt ++v +L+++l + +  + +++dn+fts++l+++L++ ++ a+Gt +  ++++P+ l++ ++ g+
   EEA22253.1 265 LAD--HGYCYYFYPASRTKGVVEVgmAKELTKTGQMVYELVQTLPKDNktYDLYLDNYFTSVNLFKALREIQVGACGTTRP-HKEFPNLLKKLKDLGS 359
                  ***..9**********999877653378****************965555*******************************.77***88876666666 PP

  DDE_Tnp_1_7 255 llaryg......gplmllkwndrkkvkllstyss....qklveskersgqki.karpklvedYnqal 310
                     +++      +++  ++w d++ v+ l+t+++    ++ +e+ +r+ qk+    p +++++ ++ 
   EEA22253.1 360 YIPYHKvcaipvNDVLCVAWQDNNIVLALTTIHTvdqtDDYIERTRRRPQKTsTNGPLVHKEFGEQA 426
                  666666666666**********************887666699999999998667888888877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (457 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       446  (0.0248759); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.22s 00:00:00.75 Elapsed: 00:00:00.41
# Mc/sec: 3381.11
//
Query:       EEA22254.1  [L=834]
Description: C6 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.4e-09   36.1   0.4    6.4e-09   35.2   0.0    1.6  2  Fungal_trans  Fungal specific transcription factor domain
    7.4e-06   26.0   7.6    1.3e-05   25.2   7.6    1.3  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.2   0.0   7.1e-13   6.4e-09       2     137 ..     241     361 ..     240     412 .. 0.83
   2 ?   -3.3   0.1       0.4   3.6e+03       9      27 ..     500     522 ..     494     538 .. 0.63

  Alignments for each domain:
  == domain 1  score: 35.2 bits;  conditional E-value: 7.1e-13
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeili..hedfsspssslwilqs 96 
                   ++ff+++hp  p++h+  ++++     +++ a+ splll a +a + ++s+++++                  ++ +l   he+ +  +++l ++q+
    EEA22254.1 241 KIFFQDIHPYVPVIHRSHLYNQW----RNDRASISPLLLEALFACAGRMSDDPAQGA----------------QWLALAtrHESSFMDVPRLSTIQA 317
                   79**************8888888....899*********999999999999999987................7888888899999**********9 PP

  Fungal_trans  97 Llllelyektss...dralherhhgvavrlarslgLhrnpsyvg 137
                   Llll           + +  + ++ +a++++++l Lh++ +  +
    EEA22254.1 318 LLLLLKARESNPkkgYYYRSWQTIKTAISMSKDLELHEHYATHQ 361
                   9999988888773334555555****************998766 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 0.4
  Fungal_trans   9 hpqf....pilhkpsflpktsse 27 
                   h ++     ++h+p++l +++s+
    EEA22254.1 500 HTHYhlaiMMVHRPQLLASKFSA 522
                   55554455888999988888333 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   7.6   1.4e-09   1.3e-05       1      31 [.      36      69 ..      36      73 .. 0.91

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 1.4e-09
                SS-HHHHHCT---ST....SSSS-HHHHHCTHHHC CS
     Zn_clus  1 haCdnCrkkKvKCda....kkPaCsnCkklnleCt 31
                +aC+ Crk+K+KCda      P C+ C +l l C+
  EEA22254.1 36 RACNGCRKRKIKCDAattnTWP-CTACLRLKLVCV 69
                69*************9887778.*********997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (834 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       582  (0.0324614); expected 358.6 (0.02)
Passed bias filter:                      426  (0.0237604); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.32s 00:00:00.96 Elapsed: 00:00:00.45
# Mc/sec: 5557.66
//
Query:       EEA22255.1  [L=213]
Description: cytoplasmic protein required for cell viability, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.8e-09   36.3   0.0    1.3e-08   34.9   0.0    1.8  1  FeS_assembly_P  Iron-sulfur cluster assembly protein


Domain annotation for each model (and alignments):
>> FeS_assembly_P  Iron-sulfur cluster assembly protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.9   0.0   7.4e-13   1.3e-08       1      73 [.      85     170 ..      85     171 .. 0.94

  Alignments for each domain:
  == domain 1  score: 34.9 bits;  conditional E-value: 7.4e-13
                     HHHHHHHHTT-B-TTTSSBCCCCT---E..EEE-T..........-EEEEEE--SSTT-TTHHHHHHHHHHHHC..STT--EEEEE CS
  FeS_assembly_P   1 keavlaaLrtVtDPelgvdlvslglvre..idieg..........gkVsvditltypacslaeairadaeaalr.alpgvevveVe 73 
                     ++++++  +t+ DPe++++l sl +v+   i+i+            +V+v it+t+ +csla+ i   ++  l+ +lp+++ v V 
      EEA22255.1  85 EQEIYDLVSTISDPEHPISLGSLAVVSLpdISISPslpanpssplRTVTVLITPTITHCSLATVIGLGVRVRLEqSLPPRFRVDVR 170
                     699***********************96669999999999999999*********************************9999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (213 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       481  (0.026828); expected 358.6 (0.02)
Passed bias filter:                      379  (0.0211389); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.46
# Mc/sec: 1386.88
//
Query:       EEA22256.1  [L=987]
Description: U5 snRNP component Snu114, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.6e-48  164.1   0.0      4e-48  163.5   0.0    1.3  1  GTP_EFTU     Elongation factor Tu GTP binding domain
    1.1e-36  126.1   8.3      2e-36  125.2   8.3    1.5  1  EFTUD2       116 kDa U5 small nuclear ribonucleoprotein compo
    4.5e-24   84.5   0.0      1e-23   83.4   0.0    1.6  1  EFG_IV       Elongation factor G, domain IV
    2.2e-19   69.3   0.0    6.2e-19   67.8   0.0    1.8  1  EFG_C        Elongation factor G C-terminus
    1.7e-09   37.9   0.0    4.9e-09   36.5   0.0    1.8  1  GTP_EFTU_D2  Elongation factor Tu domain 2
    3.2e-07   30.4   0.1    6.7e-07   29.4   0.1    1.6  1  MMR_HSR1     50S ribosome-binding GTPase
    3.6e-07   30.2   0.6    2.9e-06   27.3   0.0    2.5  3  EFG_II       Elongation Factor G, domain II
  ------ inclusion threshold ------
      0.036   13.7   0.0      0.095   12.3   0.0    1.7  1  Ras          Ras family
      0.064   12.5   0.0       0.14   11.4   0.0    1.4  1  Septin       Septin


Domain annotation for each model (and alignments):
>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  163.5   0.0     2e-51     4e-48       2     193 ..     135     455 ..     134     456 .. 0.83

  Alignments for each domain:
  == domain 1  score: 163.5 bits;  conditional E-value: 2e-51
                 CEEEEEEEESTTSSHHHHHHHHHHHTTSSCHHHHHH......HHHSTHCHSHHHHHHTSCSSCEEEEEE...TTCSSEEEEEEEESSSGGGHHHHHHHH CS
    GTP_EFTU   2 rirnigiighvDhGKtTLtdrLlyktgaiskkgeka......eeervlDtlkeErergiTiksaaisle...ketkkylinliDtPGHvdFskevirgl 91 
                 +irni+i+gh++hGKtT++d L+++t++i+++ e++      e+ r++D +  Erer+++iksa +sl    +++k+yl+n++DtPGHv+F++ev ++l
  EEA22256.1 135 QIRNIAIAGHLHHGKTTFMDMLVTQTHDINERLEQRtgrkrdEQLRYTDVHFLERERQLSIKSAPMSLVlqgTKGKSYLFNILDTPGHVNFVDEVAASL 233
                 79*****************************9998866655444556**********************9766************************** PP

                 HT-SEEEEEEETTTBSTHHHHHHHHHHHHTTTEEEEEEESCGSTHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT...........TTEEEEEEBTTTTB CS
    GTP_EFTU  92 rvlDgavlvvdaveGvepqteevlrlalkegvpiivfiNKmDrlkaelkeiveevkqklsrkeeklekygekge...........kevpvvfgSalkge 179
                 r +Dg+ lvvd+veGv+++te++++ a  e++p+ +++NK+Drl+ elk  +++++ kl+++ e+++++ e+             ++ +v+f+++l ++
  EEA22256.1 234 RLADGVALVVDVVEGVQANTEQIIKYAVLEDMPMTLVVNKVDRLILELKLPPNDAYFKLKHVIEQVNSIIENVIpgmgesrrlspEKGNVAFACGLMNW 332
                 ********************************************************999888777666666544777888888888999********** PP

                 THH................................................................................................ CS
    GTP_EFTU 180 gvk................................................................................................ 182
                 +++                                                                                                
  EEA22256.1 333 CFTlesfakmyaerhskldsaefakrlwgdifynprsrkftrkgveegskrsfvnfvlepvyklyshtisespedlketlasldiylkpsqlkldakvl 431
                 999777777777777777777777777777777777777777777777777777777777777777777777777777777777777777777777666 PP

                 .............HHHHHHHHHSH CS
    GTP_EFTU 183 .............tllealvellp 193
                               +++++v+++p
  EEA22256.1 432 lnlvceqffgpatGFVDMCVQHIP 455
                 666666666666556666666666 PP

>> EFTUD2  116 kDa U5 small nuclear ribonucleoprotein component N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  125.2   8.3     1e-39     2e-36       1     122 []       2     117 ..       2     117 .. 0.76

  Alignments for each domain:
  == domain 1  score: 125.2 bits;  conditional E-value: 1e-39
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX............XXXXXXXXXXXXXX----TTT---S--TTTTT-SSSEEEE--S-SS CS
      EFTUD2   1 ddlYDEFGNyiGpelesdeeeeseeeeeeeeeeeeeeeeeeeaekaeedeelkdeeeeeeaeeeesnavvlhedkkyypsaeevYGkdvetlvqeeDaq 99 
                 ddlYDEFGNyiG+   s+e+e  +  ++    e+ eeeeeee+e++e+ +      + +e +e +snav+lhedk+yypsa++vYG dvetlvqeeDaq
  EEA22256.1   2 DDLYDEFGNYIGEGGLSEESEAGDVPATGYVYEDLEEEEEEEEEEVERAD------QLMEVDEGPSNAVILHEDKQYYPSAQQVYGADVETLVQEEDAQ 94 
                 69**********98888766555544444444444444444233333333......3333334479********************************* PP

                 -TTS-SS--------B---SS-- CS
      EFTUD2 100 plsePiiaPvkekkfeveekdlp 122
                 pl+ePii+Pv +kkf+++e+dlp
  EEA22256.1  95 PLTEPIINPVIQKKFSLQEADLP 117
                 ********************997 PP

>> EFG_IV  Elongation factor G, domain IV
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.4   0.0   5.2e-27     1e-23       4     121 .]     724     842 ..     721     842 .. 0.92

  Alignments for each domain:
  == domain 1  score: 83.4 bits;  conditional E-value: 5.2e-27
                 ESCEE.SS-CCHCCCCCCCHTSSSHCCCCCEEEECCTTTTSSEEEEE--S....TCCCHCCCCHHHHCCCCCCTTS-TTTS--EESEEEEEEEEE--T. CS
      EFG_IV   4 ayrEtirkpvkereeklkkqsggdgqyakvileiePleegsgnefvdetk....ggqvpkeyieavekGfqealkeGplagepvtdvkvtLldgslhe. 97 
                 +    i++p  ++++++ +++++d+ +a+ i++++P+e ++ n++ d+t     +++++  + +++ +Gf + ++eGpl++ep+++ k++L+d+sl + 
  EEA22256.1 724 R----IKDPIRKVAKFFEEKYEWDKLAARSIWAFGPEE-NGPNILQDDTLpsqvDKKLLGTVRDSIIQGFSWGTREGPLCEEPIRNTKFRLTDISLADq 817
                 4....4578888999*********************76.**********96666777778899************************************ PP

                 .TTC-HHHHHHHHCHHHHHHHHCC- CS
      EFG_IV  98 .vdsseaafkpaarralkeallkAs 121
                  +++++++++p++rra+++++l+As
  EEA22256.1 818 aIYRGGGQIIPTTRRAIYSSFLMAS 842
                 *********************9985 PP

>> EFG_C  Elongation factor G C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.8   0.0   3.1e-22   6.2e-19       1      88 [.     844     932 ..     844     933 .. 0.97

  Alignments for each domain:
  == domain 1  score: 67.8 bits;  conditional E-value: 3.1e-22
                 EEEEEEEEEEEEEECCCCCCHHHHHHHCT-EEEEEEEE..TTEEEEEEEEEGGG-TTHHHCHHHCTTTS-EEEEEEEEEEE--HHHHHH CS
       EFG_C   1 vllEPivkveievpeeyvgkvisdlssrrGeiedmeqd.asgrviieaeiPlaeligfateLrslTkGegsfsmefsgYeevpgdklde 88 
                 +l+EP++ +e+  p + v+ v++ ls+rrG++++  +  ++    +++ iP+ +++gf+t+Lr  T+G++++s+ f++++ vpgd+ld+
  EEA22256.1 844 RLMEPVYACEMLGPADAVASVYTVLSRRRGHVLSDGPVaGTPLYSVRGLIPVIDSFGFETDLRIHTQGQATVSLVFDKWSVVPGDPLDR 932
                 59************************************8899*******************************************9986 PP

>> GTP_EFTU_D2  Elongation factor Tu domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.5   0.0   2.5e-12   4.9e-09       4      73 ..     508     581 ..     506     582 .. 0.97

  Alignments for each domain:
  == domain 1  score: 36.5 bits;  conditional E-value: 2.5e-12
                  EEEEEEESEEETTEEEEEEC.TCTTSEE...EEEEEEEEEEETEEESEEETTSEEEEEEEESSCCSGSSTTCEE CS
  GTP_EFTU_D2   4 algrvysGtlkkGdevrilg.ndtskke...ivtrissletfhededeavaganaGvivaikgledaiivGdtl 73 
                  a+grv+sG+ ++G+ vr+lg  ++  +e      +is ++  + ++  +++g++aG++v++ g++++i++++tl
   EEA22256.1 508 AFGRVMSGVARPGQPVRVLGeGYSLDDEedmVNATISDTWIANSRYNLPIDGVPAGNWVLLGGVDNSIMKTATL 581
                  79******************99999999*********************************************9 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.4   0.1   3.4e-10   6.7e-07       1     114 []     138     273 ..     138     273 .. 0.79

  Alignments for each domain:
  == domain 1  score: 29.4 bits;  conditional E-value: 3.4e-10
                 EEEEEESTTSSHHHHHHHHHTS.TEEESSSTTSSSSEEEEEEEETTEE............................EEEEECGGCSSHHHHHHHHHHHH CS
    MMR_HSR1   1 evaivGrpNvGKStLinaltge.kaivsdkpgtTrdinegrvklkgke............................ielvDtpGliegaseekglgkaf 70 
                 ++ai+G+   GK+t++  l+ + + i ++  + T   + +++++ + +                            ++++DtpG ++       + +++
  EEA22256.1 138 NIAIAGHLHHGKTTFMDMLVTQtHDINERLEQRTGRKRDEQLRYTDVHflererqlsiksapmslvlqgtkgksylFNILDTPGHVN-------FVDEV 229
                 59*****************998444556666777666666666333224445566888888888888899999999********555.......77777 PP

                 HHHHC.TSEEEEEEETTTTCSHHHHHHHHHHHHHTTSEEEEEEES CS
    MMR_HSR1  71 lalee.adlillvvdaseeklkpldeeleelleeakkplilvlnk 114
                 +a  + ad ++lvvd+  e+++++ e++ ++   ++ p++lv+nk
  EEA22256.1 230 AASLRlADGVALVVDVV-EGVQANTEQIIKYAVLEDMPMTLVVNK 273
                 7777769********88.7799999***99987799********8 PP

>> EFG_II  Elongation Factor G, domain II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0       6.2   1.2e+04      45      53 ..     304     312 ..     304     313 .. 0.87
   2 !   27.3   0.0   1.4e-09   2.9e-06       3      67 ..     603     666 ..     601     673 .. 0.91
   3 ?   -0.3   0.0      0.61   1.2e+03       5      32 ..     690     717 ..     688     719 .. 0.89

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 6.2
      EFG_II  45 etilsGmGe 53 
                 e ++ GmGe
  EEA22256.1 304 ENVIPGMGE 312
                 6799****9 PP

  == domain 2  score: 27.3 bits;  conditional E-value: 1.4e-09
      EFG_II   3 ePvislaiepkskadedklskaLarlleEDptlrverdeeTketilsGmGelHleivverlkrey 67 
                 e+v+++a+ep + ++  k+ + L+++ +  p +++++ ee++e ++ G Gel ++ v+  l+r y
  EEA22256.1 603 ESVFKVAVEPINPSELPKMLDGLRKINKSYPLVSTKV-EESGEHVILGTGELYMDCVLHDLRRLY 666
                 89***************************99887776.79*********************9976 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.61
      EFG_II   5 vislaiepkskadedklskaLarlleED 32 
                 ++ ++i+p++k++ + +++ L+  ++ED
  EEA22256.1 690 IMCYSITPNKKNKVTMIAEPLDDGIAED 717
                 56789****************9999999 PP

>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   4.8e-05     0.095      43     115 ..     207     275 ..     176     298 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 4.8e-05
                 ETTEEEEEEEEEETTSGGGHHHHHHHHTTESEEEEEEETTBHHHHHTHHHHHHHHHHHST.TTSEEEEEEETTT CS
         Ras  43 vdgkevkleiwDTAGqeefkslrelyyrdaegillvyditsresfenvkkwveeikrvae.envpivLvGnKvD 115
                 ++gk++ ++i+DT G  +f     +++r a+g+ lv d+ +      v+  +e+i ++a  e++p+ Lv nKvD
  EEA22256.1 207 TKGKSYLFNILDTPGHVNFVDEVAASLRLADGVALVVDVVE-----GVQANTEQIIKYAVlEDMPMTLVVNKVD 275
                 45999*********************************975.....68888888888887799**********9 PP

>> Septin  Septin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   6.9e-05      0.14       6      78 ..     138     228 ..     136     240 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 6.9e-05
                 EEEEEEBTTSSCCCCCCTTSS.SS----..............--------------S-EEEEEEEEET...TCEEEEEEEE---BSSSSSH CS
      Septin   6 tlmvvGesglGkttlintlfe.tdliee..............ekleeasekkkktveikkkkvvieed...gvklnltviDtpgfGdavdn 78 
                 ++ ++G+   Gktt+++ l++ t++i+e              + ++ +  + +++++ik++ +++  +   g    ++++Dtpg+ ++vd 
  EEA22256.1 138 NIAIAGHLHHGKTTFMDMLVTqTHDINErleqrtgrkrdeqlRYTDVHFLERERQLSIKSAPMSLVLQgtkGKSYLFNILDTPGHVNFVDE 228
                 67899*************985156677789999999888765444444457788888886655444330125667799*****99999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (987 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       608  (0.0339115); expected 358.6 (0.02)
Passed bias filter:                      537  (0.0299515); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.82u 0.31s 00:00:01.12 Elapsed: 00:00:00.48
# Mc/sec: 6167.32
//
Query:       EEA22257.1  [L=398]
Description: acetyl-CoA acetyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.5e-96  320.5   0.4    1.2e-95  319.8   0.1    1.5  2  Thiolase_N     Thiolase, N-terminal domain
    1.5e-45  153.8   2.6    1.8e-45  153.5   1.6    1.7  2  Thiolase_C     Thiolase, C-terminal domain
    2.7e-06   27.2   1.8    2.7e-06   27.2   1.8    2.2  2  ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
  ------ inclusion threshold ------
      0.072   13.4   0.2       0.27   11.5   0.0    2.0  2  Dodecin        Dodecin
       0.12   12.2   2.3        9.7    6.1   0.0    3.2  3  ACP_syn_III    3-Oxoacyl-[acyl-carrier-protein (ACP)] synthas


Domain annotation for each model (and alignments):
>> Thiolase_N  Thiolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  319.8   0.1   3.3e-99   1.2e-95       1     259 [.       6     266 ..       6     267 .. 0.98
   2 ?   -2.9   0.0      0.96   3.5e+03      30      47 ..     300     317 ..     298     328 .. 0.82

  Alignments for each domain:
  == domain 1  score: 319.8 bits;  conditional E-value: 3.3e-99
                 EEEEEEEEE--EETTSTTTTS-HHHHHHHHHHHHHHHHT.S-GGGCCEEEEEHSSCTTSTSCHHHHHHHHTTS-TTSEEEEEEHGGGHHHHHHHHHHHH CS
  Thiolase_N   1 vvivsaartpigkfggslkdlsaeeLlaealkallekag.vdpeevdevivGnvlqagegqniarqaalkagipeevpavtvnkvcsSglkavalaaqs 98 
                 v+ivs+artp+g+f gsl++lsa++L+++a+k++le+a+ v++++v+ev++Gnvl+a+ gqn+arqaal ag+ ++++++tvnkvc+Sglkav+l++q 
  EEA22257.1   6 VYIVSSARTPVGSFLGSLSSLSATQLGSHAIKGALERAEgVKADDVEEVFFGNVLSANVGQNPARQAALGAGLLDSTVCTTVNKVCASGLKAVMLGVQH 104
                 89************************************99*********************************************************** PP

                 HHTTSHSEEEEEEEEESTTS-EEETCTTTTGGSSSSEEEEEHHHHHHTEETTTTSEHHHHHHHHHHHHT--HHHHHHHHHHHHHHHHHHHHTTTTTTTB CS
  Thiolase_N  99 iaageadvvvagGvEsmsnaptaestdvrsglklgdekakdllipdgladafneehmGltaenlakkykisReeqdefAvkshqkaaaaqkagkFkdei 197
                 i++g ad+vvagG+Esmsn+p++ + ++r+g+k+g++ ++d +++dgl+da+++e mGl+ae++a++y++ Re+qde+A++s+qka+aaqk+g+++ ei
  EEA22257.1 105 IQTGGADIVVAGGMESMSNTPHYLP-SLRNGAKYGHQNLVDGIMKDGLTDAYKQELMGLSAEECAQDYGFNREQQDEYAIRSYQKAQAAQKSGELNAEI 202
                 ************************9.9************************************************************************ PP

                 E-EEEEESSSE..EEE-S-TTS-TT--HHHHHTS-BSSSTT.SS-BTTSB--BEEEEEEEEEEEH CS
  Thiolase_N 198 vPvkvkgkkgk..ktvdkdeairsevtaekLaklkpaFkke.GtvtAgnasqisDGaaavllmse 259
                 vP++++g +gk   tv++de++++ ++ +kL+++kpaF    GtvtA n+s+++DGaaav+l+se
  EEA22257.1 203 VPIELPGFRGKpgVTVSQDEEPKN-LNPDKLRAIKPAFIPGsGTVTAPNSSPLNDGAAAVVLVSE 266
                 ***********8669999999988.**************************************98 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.96
                 HHHHHHHHHTS-GGGCCE CS
  Thiolase_N  30 alkallekagvdpeevde 47 
                 a+ ++l+kagv+ +++d 
  EEA22257.1 300 AIPKALKKAGVTLDQIDA 317
                 788999999999999986 PP

>> Thiolase_C  Thiolase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       1.9   6.8e+03      26      43 ..      34      52 ..      32      63 .. 0.70
   2 !  153.5   1.6   5.2e-49   1.8e-45       1     122 [.     274     395 ..     274     396 .. 0.99

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 1.9
                HHHHHHHHHH.T--GGGES CS
  Thiolase_C 26 yaikkvlkka.gltvedid 43
                 aik +l++a g++ +d++
  EEA22257.1 34 HAIKGALERAeGVKADDVE 52
                5788888875478888876 PP

  == domain 2  score: 153.5 bits;  conditional E-value: 5.2e-49
                 ---SEEEEEEEEEE--GGGGGGHHHHHHHHHHHHHT--GGGESEEEE--SBHHHHHHHHHHHT--GGGBSTT--HHHH-B-TTTHHHHHHHHHHHHHHH CS
  Thiolase_C   1 lkplakirsyaevgvdpeilglgPayaikkvlkkagltvedidlfEinEAFaaqaLavakaldldlekvNvnGGaialGHPlGasGaRivvtllselkk 99 
                 lkp+aki  +a ++++p++++++Pa ai+k+lkkag+t+++id+fEinEAF+++aLa++k l+l ++kvN++GGa+a+GHPlGasGaRi+vtll  lk 
  EEA22257.1 274 LKPIAKILGFADAAQQPSKFTTSPALAIPKALKKAGVTLDQIDAFEINEAFSVVALANMKLLNLPEDKVNIHGGAVAIGHPLGASGARILVTLLGVLKA 372
                 589************************************************************************************************ PP

                 CTTSEEEEEEEETTTEEEEEEEE CS
  Thiolase_C 100 eggklgvaalCigggqgvalvie 122
                 +ggklg a +C+ggg + alv+e
  EEA22257.1 373 KGGKLGCAGICNGGGGAGALVLE 395
                 ********************997 PP

>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.2   1.8   7.6e-10   2.7e-06     169     207 ..      85     123 ..      10     128 .. 0.83
   2 ?   -3.7   0.8       1.9   6.9e+03     239     250 ..     386     397 ..     381     397 .. 0.85

  Alignments for each domain:
  == domain 1  score: 27.2 bits;  conditional E-value: 7.6e-10
                    EEEESGGGHHHHHHHHHHHHHHTTS-SEEEEEEEE---S CS
  ketoacyl-synt 169 vtvdtACsSslvavhaavqslrsgeadvalaGGvelllt 207
                     tv   C+S+l+av + vq++++g ad+++aGG+e + +
     EEA22257.1  85 TTVNKVCASGLKAVMLGVQHIQTGGADIVVAGGMESMSN 123
                    577789*****************************8865 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 1.9
                    B-EEEEEEEEEC CS
  ketoacyl-synt 239 GEGvGavvLkrl 250
                    G G+Ga+vL++l
     EEA22257.1 386 GGGAGALVLESL 397
                    789******975 PP

>> Dodecin  Dodecin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       1.2   4.3e+03      17      27 ..      34      44 ..      33      47 .. 0.87
   2 ?   11.5   0.0   7.6e-05      0.27      17      41 ..     299     323 ..     294     333 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 1.2
                HHHHHHHHHHH CS
     Dodecin 17 dAiqnAiaeAs 27
                +Ai+ A+++A+
  EEA22257.1 34 HAIKGALERAE 44
                69******996 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 7.6e-05
                 HHHHHHHHHHHHH-SSEEEEEEEEE CS
     Dodecin  17 dAiqnAiaeAsktlrnirwveVket 41 
                  Ai +A+++A  tl++i+ +e++e 
  EEA22257.1 299 LAIPKALKKAGVTLDQIDAFEINEA 323
                 59********************985 PP

>> ACP_syn_III  3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.0    0.0027       9.7       3      39 ..      87     123 ..      85     132 .. 0.88
   2 ?    3.5   0.0     0.018        65      53      64 ..     255     266 ..     250     280 .. 0.81
   3 ?   -0.2   0.5      0.26   9.5e+02      53      62 ..     386     395 ..     380     397 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0027
                  EE-GGGHHHHHHHHHHHHHHTTS-SEEEEEEEEEGGG CS
  ACP_syn_III   3 lnaaCsgfvyalsvAdaliesgaakrvLvigaetlsk 39 
                  +n++C++ + a+ +  + i++g a  v+  g e +s+
   EEA22257.1  87 VNKVCASGLKAVMLGVQHIQTGGADIVVAGGMESMSN 123
                  799*******************988888777788876 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.018
                  -EEEEEEEEEEE CS
  ACP_syn_III  53 GDGAgAvvleas 64 
                   DGA+Avvl  +
   EEA22257.1 255 NDGAAAVVLVSE 266
                  6*******9876 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 0.26
                  -EEEEEEEEE CS
  ACP_syn_III  53 GDGAgAvvle 62 
                  G GAgA+vle
   EEA22257.1 386 GGGAGALVLE 395
                  78******98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (398 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       474  (0.0264376); expected 358.6 (0.02)
Passed bias filter:                      388  (0.0216409); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2774.12
//
Query:       EEA22258.1  [L=429]
Description: ZIP family zinc transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      3e-49  168.1   3.2    3.7e-49  167.7   3.2    1.1  1  Zip       ZIP Zinc transporter
  ------ inclusion threshold ------
       0.12   12.6   0.0       0.23   11.7   0.0    1.5  1  MAP17     Membrane-associated protein 117 kDa, PDZK1-interact
       0.22   11.3   4.4       0.22   11.3   0.6    2.7  2  PsbH      Photosystem II 10 kDa phosphoprotein


Domain annotation for each model (and alignments):
>> Zip  ZIP Zinc transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  167.7   3.2   6.2e-53   3.7e-49       3     332 ..      61     425 ..      59     426 .. 0.77

  Alignments for each domain:
  == domain 1  score: 167.7 bits;  conditional E-value: 6.2e-53
         Zip   3 lkilaiiaililsllgllgpllvpkiskl.lsklllslllafavGvllgtaflhLlPealealeesqleeehth...plagllvllGflllllvekllt 97 
                 + + a+++ilils l++++p+l ++   l  ++ +l++   f+ Gvl++taf+hLlP a+++l +s+l    th    +ag++++l+ +l+ +ve +  
  EEA22258.1  61 AHVFALFLILILSTLACSFPILARRFPGLpIPRHFLFFSRHFGTGVLIATAFVHLLPTAFNSLLNSCLPPFWTHgypAMAGFIAMLSVFLVVTVEMFFA 159
                 5689***********************9999************************************9875555899******************9988 PP

         Zip  98 mivek.......................ksshkektpkkasssss..........esaakksvsndkveeseekedhvaeadtdadskeelrngkqeks 163
                    +                        k++  e+  + ++++++          + + + sv+nd   ++ee  +    +         +   +q  +
  EEA22258.1 160 SQGAAhvhgkdydeliggvpvkdnrkepKHRGREEYIHLSNQDQAatesliqsptATGQSASVNNDDGLDMEELGS----Y------ADDEPIPHQRRT 248
                 7665567888888888888776666544222222222222222222222222222223333333333333333322....2......222222233333 PP

         Zip 164 esekeqaseeedkeklaslkvraiilllglilHsfidGLAlGvssssstgislfiAvllHelpeelglgaiLlkag.....lsrkkavllnllfaltap 257
                 ++  + ++   + ++++++ +  ++l+ g+ +Hs+++G+Al+  ++ +++i+l++A+++H+ +e+++lg+++++        s+ k +l++++++ t+p
  EEA22258.1 249 KHVRQGNEPVTQLQNPQRQLLQCLLLEAGILFHSIFIGMALS-VATGTSFIVLLVAISFHQTFEGFALGSRIASLIpslfpPSSFKPWLMACAYGTTTP 346
                 3333333344556678888889********************.677889*********************999876222114678899*********** PP

         Zip 258 lGiliGilvrs..isessgaeivsgillalsaGtflYvalvellphEllnek..gssslkqsllqllglllGfalmlll 332
                 +G +iG+++ +  ++ s + +i+ g  +a+s+G++l  +lvell++++l+e+  ++ + +  + + l++l G++lm+++
  EEA22258.1 347 IGQAIGLVLHNmyDPASATGLIMVGFTNAISSGLLLFAGLVELLAEDFLSEEsyETLNGWRRVEACLAVLGGAMLMSIV 425
                 ********999*****************************************997778899***************986 PP

>> MAP17  Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   3.9e-05      0.23       7      64 ..     107     167 ..     103     226 .. 0.65

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 3.9e-05
       MAP17   7 lllllllllspaeaQqatekrlkP.WlvGliAvvgFLfl..vfvlllvnrvWcskaraede 64 
                 l+  +++ l p      +++ l P W  G  A++gF+ +  vf+++ v+++  s+  a+  
  EEA22258.1 107 LIATAFVHLLPTAFNSLLNSCLPPfWTHGYPAMAGFIAMlsVFLVVTVEMFFASQGAAHVH 167
                 666677777777777778888999************9883456666678888887655443 PP

>> PsbH  Photosystem II 10 kDa phosphoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.2      0.22   1.3e+03      34      44 ..      63      73 ..      60      78 .. 0.75
   2 ?   11.3   0.6   3.6e-05      0.22      26      46 ..     137     157 ..     128     160 .. 0.84

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.22
        PsbH 34 LflvfLviilq 44
                 f++fL+ il 
  EEA22258.1 63 VFALFLILILS 73
                57888888875 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 3.6e-05
        PsbH  26 pvmavfilLflvfLviilqiy 46 
                 p ma+fi+++ vfLv+  +++
  EEA22258.1 137 PAMAGFIAMLSVFLVVTVEMF 157
                 99*************988865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (429 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       424  (0.0236488); expected 358.6 (0.02)
Passed bias filter:                      252  (0.0140554); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.24s 00:00:00.74 Elapsed: 00:00:00.41
# Mc/sec: 3145.84
//
Query:       EEA22259.1  [L=552]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     6e-102  341.0   7.1     6e-102  341.0   7.1    1.6  1  Atg14     Vacuolar sorting 38 and autophagy-related subunit 1
  ------ inclusion threshold ------
      0.014   14.8   5.1      0.027   13.9   5.1    1.4  1  Not3      Not1 N-terminal domain, CCR4-Not complex component


Domain annotation for each model (and alignments):
>> Atg14  Vacuolar sorting 38 and autophagy-related subunit 14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  341.0   7.1  6.7e-106    6e-102       1     318 [.       3     364 ..       3     366 .. 0.99

  Alignments for each domain:
  == domain 1  score: 341.0 bits;  conditional E-value: 6.7e-106
       Atg14   1 CplCerss...rpfiCesClrngperlyelrerlaklksekeslkkkiekalegke................eaeqledkiknkkakleelksliadlr 80 
                 C++C +s+   +pf+C++C+r+   +ly+lr ++a++++ekes++k++e+a++g++                ++++++++++n+k++++  ++++a+++
  EEA22259.1   3 CSICTCSAsnrTPFYCPTCARS---HLYTLRYENARVLLEKESIGKEVEAAVAGNTgvqrrqqqqnantnanNNTRQASRERNLKWDAQAAQTEQARSS 98 
                 9****998899***********...**********************************************9999************************ PP

       Atg14  81 erlqelkdklsqlkkeieekkkklaklsdklkkRrsdleslqneleerrkkqiaklqdaikrieqklsslssktlesrsslcselaklyglrrtsyerg 179
                 +r++ ++d++++l++ ie++k+++++++ + k+Rrsd+es++++l+err++ +a++q+ ikr+e+ ++sl++kt+esr++lc+e+a lyglr+      
  EEA22259.1  99 DRIRAMRDCIETLRSDIEQRKAQIRHMKLQQKQRRSDAESANFQLSERRNAALASIQNGIKRTEHLWHSLHNKTAESRIFLCREAAFLYGLRQ------ 191
                 *********************************************************************************************...... PP

       Atg14 180 kwvfskngeseesytIggiplpdlrdlnafpaeeIsasLsyiaqLlaLvshyLsirLPaeltlphscqpi............................. 249
                 +  +++ g+ +e+y Igg++++dlr ln++++++Is++Ls+i++Ll LvshyLs+rLPae++lph+++ i                             
  EEA22259.1 192 EVGKREGGRKSEKYYIGGVQIVDLRSLNGASPPQISTALSNISHLLILVSHYLSLRLPAEIILPHRNHAIptiftpaasyssaqdnlsdvyhpynhskp 290
                 45578899************************************************************99***************************** PP

       Atg14 250 ........rplfiekslpkls...peteseflegvalLayniawLcrtqgvnsleleptqldtlenlcdllklLysllvs 318
                         rpl++ek+lpkl+   p+t++ f+egv+lLa+n++wLcrtqg+n+      ++d++e++c+++k++++llvs
  EEA22259.1 291 gdtrkhraRPLSVEKTLPKLVkeePATYALFIEGVSLLAWNVSWLCRTQGLNI------GSDSWEDICNIGKNMWQLLVS 364
                 *****************************************************......9*****************986 PP

>> Not3  Not1 N-terminal domain, CCR4-Not complex component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   5.1     3e-06     0.027     109     195 ..      85     174 ..      47     191 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 3e-06
        Not3 109 aaaekldpkekekeearewlkdaideLneqvekleaeieklsskkkkkkkskeka...rveeleklierhkfhieklelllrlleneele 195
                  +a+ ++ ++ + ++ ++ ++d+i++L++ +e+ +a+i +++ ++k++++++e+a     e+ ++ + + +  i++ e+l + l+n++ e
  EEA22259.1  85 WDAQAAQTEQARSSDRIRAMRDCIETLRSDIEQRKAQIRHMKLQQKQRRSDAESAnfqLSERRNAALASIQNGIKRTEHLWHSLHNKTAE 174
                 44455678888899999************************99998888755444363445566778999999**********9998764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (552 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1838  (0.102515); expected 358.6 (0.02)
Passed bias filter:                      529  (0.0295053); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.30s 00:00:00.97 Elapsed: 00:00:00.46
# Mc/sec: 3622.16
//
Query:       EEA22260.1  [L=614]
Description: Hsp70 chaperone (HscA), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     6e-227  754.6   7.6   6.7e-227  754.4   7.6    1.0  1  HSP70     Hsp70 protein
    2.6e-16   59.3   0.1    2.8e-15   56.0   0.0    2.0  2  MreB_Mbl  MreB/Mbl protein
    0.00033   20.4   0.0    0.00072   19.3   0.0    1.5  1  FGGY_C    FGGY family of carbohydrate kinases, C-terminal dom
  ------ inclusion threshold ------
          5    7.6   7.1        1.2    9.6   1.8    2.2  2  MRC1      MRC1-like domain


Domain annotation for each model (and alignments):
>> HSP70  Hsp70 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  754.4   7.6  1.5e-230  6.7e-227       1     594 [.       9     611 ..       9     614 .] 0.97

  Alignments for each domain:
  == domain 1  score: 754.4 bits;  conditional E-value: 1.5e-230
                 EEEEEEXSSEEEEEEEETTEEEEEXXTTSXSSEESEEEEXTTSEEETHHHHHCTTTTGGGEEEXGGGTTTXBTTSHHHHHHHTTXSSEEEEETTSBEEE CS
       HSP70   1 viGiDLGttnsvvavmeggkievianeegnrttPsvvaFtkkerlvGeaAkrqavtnpkntvfsvKrliGrkfsdpevqkeikelpykvvkkengkavv 99 
                 +iGiDLGtt+s+va  eg ++e+iane+g+ ttPs+v+Ft+kerl+GeaAk+qa++np+nt+f++KrliGr+f+dp+v+k+i+++p+kvv +  g+++v
  EEA22260.1   9 AIGIDLGTTYSCVANYEGSNVEIIANEQGSFTTPSFVSFTDKERLIGEAAKNQAAMNPENTIFDIKRLIGRRFEDPVVKKDIESWPFKVVDQ-GGNPMV 106
                 59****************************************************************************************99.9***** PP

                 EEEETTE..EEEHHHHHHHHHHHHHHHHHHHHTSBEEEEEEEEXTTXXHHHHHHHHHHHHHTTXEEEEEEEHHHHHHHHHHTC..CSSSCEEEEEEEEX CS
       HSP70 100 eveaage..kftpeqisamvLkklketaeaylgkkvtdavitvPaYfndaqRqatkdAgkiAGLnvlRivNepTAaalaYGld..kkdkernvlvyDlG 194
                 eve+ +e  +f+p++is+mvL+k+ke ae+ lgkkv++avitvPaYfnd+qRqatkdAg+iAGLnvlRi+NepTAaa+aYGl   k+dkernvl+yDlG
  EEA22260.1 107 EVEYLNEtkTFSPQEISSMVLTKMKEVAETKLGKKVSKAVITVPAYFNDNQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLGsgKSDKERNVLIYDLG 205
                 *****9999*************************************************************************733566*********** PP

                 SSXEEEEEEEEETTEEEEEEEEEETTXSHHHHHHHHHHHHHHHHHHHHSXXGGGSHHHHHHHHHHHHHHHHHTTTSSCSEEEEEEEEEETTTEEEEEEE CS
       HSP70 195 ggtfdvSilelekGvfevkaTagDthlGGedfDealvehlveefkkkegidlskdkkalqrlkeaaekaKkeLSsskqteinleietvdedgkdlsekl 293
                 ggtfdvS+l+++ Gvf vkaTagDthlGG+dfD++l+eh+ +ef +k++ dls+d++al+rl++a+e+aK++LS+  +t++++ei+++++ g+d++ ++
  EEA22260.1 206 GGTFDVSLLNIQGGVFTVKATAGDTHLGGQDFDTNLLEHFKKEFTRKTKKDLSNDPRALRRLRTACERAKRTLSN--ATQTTVEIDSLFD-GEDFNAQI 301
                 ***************************************************************************..788899999***9.******** PP

                 EHHHHHHHHHHHHHHTHHHHHHHHHHCTEEGGGCSEEEEESGGGGSHHHHHHHHHHTT.CHHBSSSHTTTHHHHHHHHHHHHHCTC...GCSHCCEEEE CS
       HSP70 294 sRakfeelvedllertlepvekalkdaklkkeeidevvlvGGstRiPkvqelvkelfg.kepsktvnpDeavaiGAAvqagvlsge...eevkdllllD 388
                 +Ra+fe+l+++ ++ tl+pv+++lkd+++ k+ +de+vlvGGstRiP++q+l++++f+ k+++k++npDeava+GAAvqag+lsg    ee++dllllD
  EEA22260.1 302 TRARFEDLNAKAFAGTLDPVQQVLKDSGIAKSAVDEIVLVGGSTRIPRIQKLLSDFFDgKKLEKSINPDEAVAYGAAVQAGILSGMatsEETSDLLLLD 400
                 *********************************************************88**************************8777899******* PP

                 BESS-EEEEETTTEEEEEESTTCBSSEEEEEEEEESSTTSSSEEEEEEESSSSBGGGSEEEEEEEEECESSCSTTCSEEEEEEEEETTSCEEEEEEETT CS
       HSP70 389 vtpLslgietlggvmtkliernttiptkksqvfstaadnqtaveievlqgerelvkdnkllgsfeldgippaprGvpqieVtfdidanGiltvsakdke 487
                 v+pLslg+ ++g+++  + +r +t+pt k+++f+t+ dnq++v+  v+qger+  +dn++lg+f+l  ipp+ +G+  +eV f++d+nGil+v+a++k+
  EEA22260.1 401 VVPLSLGVAMEGNIFAPVVPRGQTVPTIKKRTFTTVVDNQQTVQFPVYQGERTNCEDNTSLGEFTLAPIPPMRAGEAALEVVFEVDVNGILKVTATEKS 499
                 *************************************************************************************************** PP

                 TCCEEEEEEECCSS.SBHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH..GGGSTHHHHHHHHHHHHHHHCHTTSSC..HHHHHH CS
       HSP70 488 tgkeeeitieaseg.lseeeiekmvkdaeesaeedkkkkeaieakneaeelvyslekkleee..aekvseaekekvesaieeLkeeleeee..keeiea 581
                 +g++++iti+++ g ls++eie+m++da +++++d++  ++ ea++++e+++ ++e+ +++   + k+++ +kek+esa+++   +le ++   +++++
  EEA22260.1 500 SGRTANITISNAVGkLSSTEIEQMINDAAKFKSSDEEFSKKFEARQQLESYISRVEEIISDPtmSLKLKRGNKEKIESALSDAMGQLEIDDstPDDLKK 598
                 ***********9999*********************************************997778899999999999999988877655544788888 PP

                 HHHHHHHHHHHHH CS
       HSP70 582 kteelkkvvekia 594
                 k  +lk++++k +
  EEA22260.1 599 KELALKRLITKAM 611
                 8888888877765 PP

>> MreB_Mbl  MreB/Mbl protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0     0.035   1.6e+02       3      16 ..       9      24 ..       7      70 .. 0.64
   2 !   56.0   0.0   6.3e-19   2.8e-15      76     316 ..     124     378 ..     117     386 .. 0.80

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.035
                EEEEEE-SSEEEE..E CS
    MreB_Mbl  3 dlgiDLGtantlv..y 16
                 +giDLGt+   v  y
  EEA22260.1  9 AIGIDLGTTYSCVanY 24
                69*******9988432 PP

  == domain 2  score: 56.0 bits;  conditional E-value: 6.3e-19
                 HHHHHHHHHHHTSS-.SS--EEEEEE-SS--HHHHHHHHHHHHHTT-SEEEEEEHHHHHHHHTT--T...TSSS-EEEEEE-SS-EEEEEEETTEEE.E CS
    MreB_Mbl  76 ellkyfikkvkkkks.lskprvvicvPsgiteverrAvkeaakkaGarevllieeplaAAiGaglpv...eepsgnmvvdiGggttevavislggiv.t 169
                 +++ + +k+v+++k   + ++ vi+vP   ++ +r+A k+a   aG +   +i+ep aAAi  gl     ++ +  ++ d+Gggt +v+++ ++g v t
  EEA22260.1 124 SMVLTKMKEVAETKLgKKVSKAVITVPAYFNDNQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLGSgksDKERNVLIYDLGGGTFDVSLLNIQGGVfT 222
                 455555666666444157789****************************************999865111455677999************99765513 PP

                 EEE....ES-SHHHHHHHHHHHHHHHHSEE--H......HHHHHHHHHH-BSS--HHHH.EEEEEEEETTTTCEEEEEEEHHHHHHHHHHHHHHHHHHH CS
    MreB_Mbl 170 sks....vrvaGdeldeaiikyirkkynlliGe......rtaekikieigsavkeeeee.kmeikGrdlvtglpkevevsseevrealkepvsaiveav 257
                  k+     +++G+++d +++++ +k+++    +      r  ++++++   a+ + ++  +++++   l  g   +++++ ++ ++  +++++  ++ v
  EEA22260.1 223 VKAtagdTHLGGQDFDTNLLEHFKKEFTRKTKKdlsndpRALRRLRTACERAKRTLSNAtQTTVEIDSLFDGEDFNAQITRARFEDLNAKAFAGTLDPV 321
                 3332222689***************99765544111111566677777777777666556999999********************************* PP

                 HHHHHTS-HHHHHHHHHH-EEEESGGGGSBTHHHHHHHHHS.S-EEE-SSTTTHHHHHHH CS
    MreB_Mbl 258 kevLektppeLaadivdrgivltGGgallkgldkllseetg.lpvkvaedpltcvakGtg 316
                 ++vL++    +a+  vd+ ivl+GG++ +  ++klls+ ++  + + + +p ++va G++
  EEA22260.1 322 QQVLKDS--GIAKSAVDE-IVLVGGSTRIPRIQKLLSDFFDgKKLEKSINPDEAVAYGAA 378
                 ****986..567777775.9999***************9962567889999999999986 PP

>> FGGY_C  FGGY family of carbohydrate kinases, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.0   1.6e-07   0.00072     145     196 ..     312     383 ..     264     384 .. 0.76

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 1.6e-07
      FGGY_C 145 d..................sgkpldrlavdGGgskndllmqllAdilg.vpVerpkt.aeatalGaAilAav 196
                 +                   ++++d+++++GG ++ + +++ll d +  +++e+  + +ea+a GaA+ A++
  EEA22260.1 312 KafagtldpvqqvlkdsgiAKSAVDEIVLVGGSTRIPRIQKLLSDFFDgKKLEKSINpDEAVAYGAAVQAGI 383
                 33333333333345555555667************************88****99999***********985 PP

>> MRC1  MRC1-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.3      0.23     1e+03      57     117 ..     243     305 ..     232     325 .. 0.65
   2 ?    9.6   1.8   0.00027       1.2      37     103 ..     517     582 ..     510     613 .. 0.72

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.23
        MRC1  57 elaaekakeereeDdkevekllkdittGglRkrrrr.ag.gndldlsDs..Ddeeaelrrrkrrr 117
                 e+ ++ + ++ ++D +++ + l++  t   R +r   +  +  ++++ s  D e+    +  r+r
  EEA22260.1 243 EHFKKEFTRKTKKDLSNDPRALRRLRTACERAKRTLsNAtQTTVEID-SlfDGED-FNAQITRAR 305
                 45566677788888888888888888888888886533333333555.3335555.234444444 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00027
        MRC1  37 daeleeliDdesedeevdkdelaaekakeereeDdkevekllkdittGglRkrrrraggndldlsDs 103
                 + e+e++i+d+++ +  d++  +++ a+++ e   ++ve+++ d t   l+ +r+++++ +  lsD+
  EEA22260.1 517 STEIEQMINDAAKFKSSDEEFSKKFEARQQLESYISRVEEIISDPTM-SLKLKRGNKEKIESALSDA 582
                 5699********999999999***********************887.6666786433444455543 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (614 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       922  (0.0514251); expected 358.6 (0.02)
Passed bias filter:                      611  (0.0340789); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.66u 0.29s 00:00:00.95 Elapsed: 00:00:00.46
# Mc/sec: 4018.80
//
Query:       EEA22261.1  [L=610]
Description: polybromo-1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.3e-31  107.2   0.2    3.8e-18   65.3   0.2    2.4  2  Bromodomain  Bromodomain
  ------ inclusion threshold ------
        4.6    7.0   7.6       0.45   10.3   2.9    1.7  2  Pox_Ag35     Pox virus Ag35 surface protein


Domain annotation for each model (and alignments):
>> Bromodomain  Bromodomain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.3   0.2   4.2e-22   3.8e-18      12      83 ..      60     131 ..      47     132 .. 0.94
   2 !   39.5   0.0     5e-14   4.5e-10      16      83 ..     240     317 ..     229     318 .. 0.86

  Alignments for each domain:
  == domain 1  score: 65.3 bits;  conditional E-value: 4.2e-22
                  TCGGGGCSTT-GCCSTTHHHH.SS---HHHHHHHHHTT--SSHHHHHHHHHHHHHHHHHHSHTTSHHHHHHH CS
  Bromodomain  12 klaepFlepvdpeefpdyyavikkPldLstIkkklesnkYksladfeadlkllfsNarkyngegsviyelae 83 
                   +a+ F e +d++++pdyy+vi  P++L+++ +kl+++ Y +l+++e dlk+l+sNa+kyn++g+ ++++ae
   EEA22261.1  60 IIASNFYELPDKKKYPDYYKVIGLPISLNQVIDKLNKHRYATLTELESDLKRLVSNAKKYNEKGTMLFADAE 131
                  4899999999***********************************************************997 PP

  == domain 2  score: 39.5 bits;  conditional E-value: 5e-14
                  GGCSTT-GCCSTTHHHH.SS---HHHHHHHH..........HTT--SSHHHHHHHHHHHHHHHHHHSHTTSHHHHHHH CS
  Bromodomain  16 pFlepvdpeefpdyyavikkPldLstIkkkl..........esnkYksladfeadlkllfsNarkyngegsviyelae 83 
                  pFl  +d+  +++yy++i++P++L  I k +          ++  + +++ f ++++ ++ Nar++n+e+s+i +l++
   EEA22261.1 240 PFLYKPDKNLYKEYYEIIQHPVSLRSILKQVrgiegrkphsHKTAFPTWQLFADEMEYVWGNAREFNEEDSEIVDLVN 317
                  788888***********************7777765555556666778************************998875 PP

>> Pox_Ag35  Pox virus Ag35 surface protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.2      0.69   6.1e+03      53      63 ..      29      39 ..       8      61 .. 0.56
   2 ?   10.3   2.9     5e-05      0.45      80     139 ..     167     226 ..      95     231 .. 0.70

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 0.69
    Pox_Ag35 53 kkkrattprkk 63
                k+  ++tp+k+
  EEA22261.1 29 KTDDIETPQKT 39
                22223333333 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 5e-05
    Pox_Ag35  80 aeeeeledseedeenendedeseesvqaeeeksnesteddadeldeSdLkvatenIikdl 139
                 +e  e ed eed +n++d+ e +++ ++ +++   + ed++ + +   +++a ++Ii+++
  EEA22261.1 167 TETPENEDGEEDGDNQEDNAEADAEDDKASDQELDQGEDEELNFEGDTIQLAQDKIISEM 226
                 22223334444444443333333333333333333367888888889999******9998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (610 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       799  (0.0445647); expected 358.6 (0.02)
Passed bias filter:                      572  (0.0319036); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.31s 00:00:00.98 Elapsed: 00:00:00.48
# Mc/sec: 3834.08
//
Query:       EEA22262.1  [L=115]
Description: cell cycle regulatory protein Cks/Suc1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-34  117.9   1.8    2.2e-34  117.5   1.8    1.1  1  CKS       Cyclin-dependent kinase regulatory subunit


Domain annotation for each model (and alignments):
>> CKS  Cyclin-dependent kinase regulatory subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.5   1.8   1.2e-38   2.2e-34       1      67 [.      32     107 ..      32     108 .. 0.95

  Alignments for each domain:
  == domain 1  score: 117.5 bits;  conditional E-value: 1.2e-38
         CKS   1 ieYSdkyeddeyeYRhViLpkellkkipks.........rlLsekewraLgIqqskgWehyeihkpephiLlfrrp 67 
                 i+YS++y+d+eyeYRhV Lpk++lkkip++         +lL e+ewr+LgI+qs+gWehye+h+pephiLlf+rp
  EEA22262.1  32 IHYSSRYSDSEYEYRHVQLPKNMLKKIPQEyfdtskgtlKLLWEEEWRGLGITQSLGWEHYEVHEPEPHILLFKRP 107
                 8****************************66667788889***********************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (115 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       417  (0.0232584); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.44
# Mc/sec: 786.50
//
Query:       EEA22263.1  [L=205]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.8e-11   44.4   0.0    3.3e-11   43.6   0.0    1.4  1  Thioredoxin_4  Thioredoxin
  ------ inclusion threshold ------
       0.18   11.6   3.2        1.2    8.9   0.2    2.7  2  DSBA           DSBA-like thioredoxin domain


Domain annotation for each model (and alignments):
>> Thioredoxin_4  Thioredoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.6   0.0   3.7e-15   3.3e-11      13     164 ..      20     200 ..      17     202 .. 0.77

  Alignments for each domain:
  == domain 1  score: 43.6 bits;  conditional E-value: 3.7e-15
                    -SEEEEEEE-TT-HHHHHHHHH....HHHHHHHHHHTT.SEEEEEEE-..---STTTHHHHHHHTT--TTHHHHHHHHHHHHTHHHHTTS-..... CS
  Thioredoxin_4  13 ApvtvieyedlrCphCakfeee....veklleeyidtG.kvkfiirdfpldkekeslkaamaarcageespeaflaikallysqqeewaes..... 98 
                     p+t+++y d+ Cp  ak++++    v++l++e    G kv++i+r+ + + + +s+    a  +++++ pe+f++++++l+++q+e   +     
     EEA22263.1  20 SPHTIELYLDYVCPFSAKLFNTfytsVKPLITEK--YGsKVQVIFRQQIQPWHPSSTLVHEAGAAVLKVAPEKFWDFSQVLFKEQKEYFDEkvvne 113
                    69***************96665111145444333..357************9999***************************99999888867555 PP

                    ..HHHHH.........................HHHH.HTS-------HHHHHHHHHHHHHHT--SS-EEEETT...EEE-TT--HHHHHHHH CS
  Thioredoxin_4  99 ..lkelaae....................aldkdek.feacleeekldalveaeskeakkagiestPtfiing...ekveepqtyeelkali 164
                            +                    +l   ++  e + +   + ++++ ++k  +  g+  tPt++ +g   + ++ + t +++ +++
     EEA22263.1 114 irN-----DtykrlaalaatvgvdekkvyDLLVIKDgGEGANKGNGVTNDIKLMVKANRVIGVHVTPTVFFDGieeKSISSSFTSDQWDEWL 200
                    441.....2344445557778888888885555555245555777899999999999999**********8763225599999999999887 PP

>> DSBA  DSBA-like thioredoxin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.2   0.00013       1.2       1      20 [.      23      42 ..      23      65 .. 0.79
   2 ?    2.8   0.3    0.0099        89     121     139 ..     117     135 ..      63     199 .. 0.54

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00013
                EEEEEEBTTBHHHHHHHHHH CS
        DSBA  1 tvdeffDvlCPyCylgkerl 20
                t++++ D++CP++   +  +
  EEA22263.1 23 TIELYLDYVCPFSAKLFNTF 42
                79***********8777655 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.0099
                 SSHHHHHHHHHHTTS.HHH CS
        DSBA 121 tddqellevaekaGldaee 139
                 ++ + l+++a  +G+d ++
  EEA22263.1 117 DTYKRLAALAATVGVDEKK 135
                 2223355555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (205 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       695  (0.038764); expected 358.6 (0.02)
Passed bias filter:                      543  (0.0302861); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.31s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 1374.34
//
Query:       EEA22264.1  [L=167]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.1e-08   35.5   0.0    1.3e-08   35.1   0.0    1.1  1  Thioredoxin_4  Thioredoxin
  ------ inclusion threshold ------
       0.11   12.2   1.5       0.85    9.4   0.2    2.2  2  DSBA           DSBA-like thioredoxin domain


Domain annotation for each model (and alignments):
>> Thioredoxin_4  Thioredoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.1   0.0   1.5e-12   1.3e-08      13     103 ..      20     115 ..      17     144 .. 0.76

  Alignments for each domain:
  == domain 1  score: 35.1 bits;  conditional E-value: 1.5e-12
                    -SEEEEEEE-TT-HHHHHHHHH....HHHHHHHHHHTT.SEEEEEEE-..---STTTHHHHHHHTT--TTHHHHHHHHHHHHTHHHHTTS-..HHH CS
  Thioredoxin_4  13 ApvtvieyedlrCphCakfeee....veklleeyidtG.kvkfiirdfpldkekeslkaamaarcageespeaflaikallysqqeewaes..lke 101
                     p+t+++y d+ Cp  ak++++    v++l++e    G kv++i+r+ + + + +s+    a  +++++ pe+f++++++l+++q+e   +  ++e
     EEA22264.1  20 SPHTIELYLDYVCPFSAKLFNTfytsVKPLITEK--YGsKVQVIFRQQIQPWHPSSTLVHEAGAAVLKVAPEKFWDFSQVLFKEQKEYFDEkvVNE 113
                    79***************96665111145444333..357************9999****************************9999887734333 PP

                    HH CS
  Thioredoxin_4 102 la 103
                    + 
     EEA22264.1 114 IR 115
                    33 PP

>> DSBA  DSBA-like thioredoxin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.2   9.5e-05      0.85       1      20 [.      23      42 ..      23      65 .. 0.79
   2 ?    2.2   0.1     0.014   1.3e+02     100     131 ..      83     116 ..      52     140 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 9.5e-05
                EEEEEEBTTBHHHHHHHHHH CS
        DSBA  1 tvdeffDvlCPyCylgkerl 20
                t++++ D++CP++   +  +
  EEA22264.1 23 TIELYLDYVCPFSAKLFNTF 42
                79***********8777655 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.014
                 H..GHHHHHHHHHHHHHTSSS-TSSHHHHHHHHH CS
        DSBA 100 g..laekvvrelfealwsegqaitddqellevae 131
                    +a ++++++ + l++e+++ +d++++ e+ +
  EEA22264.1  83 VlkVAPEKFWDFSQVLFKEQKEYFDEKVVNEIRN 116
                 2335567888888888888888888888777655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (167 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       721  (0.0402142); expected 358.6 (0.02)
Passed bias filter:                      591  (0.0329634); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.24s 00:00:00.68 Elapsed: 00:00:00.40
# Mc/sec: 1257.89
//
Query:       EEA22265.1  [L=419]
Description: hypothetical protein PMAA_060450 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (419 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       456  (0.0254337); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.62u 0.25s 00:00:00.87 Elapsed: 00:00:00.49
# Mc/sec: 2562.71
//
Query:       EEA22266.1  [L=419]
Description: hypothetical protein PMAA_060450 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (419 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       456  (0.0254337); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.46
# Mc/sec: 2717.57
//
Query:       EEA22267.1  [L=390]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.1e-25   89.7   5.1    2.3e-25   88.7   5.1    1.5  1  DUF3844        Domain of unknown function (DUF3844)
  ------ inclusion threshold ------
      0.016   15.6  10.3      0.035   14.5  10.3    1.6  1  EGF_2          EGF-like domain
       0.18   12.2  11.7      0.075   13.5   8.7    1.9  2  EGF_alliinase  Alliinase EGF-like domain


Domain annotation for each model (and alignments):
>> DUF3844  Domain of unknown function (DUF3844)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.7   5.1   3.9e-29   2.3e-25       1     105 []     291     381 ..     291     381 .. 0.96

  Alignments for each domain:
  == domain 1  score: 88.7 bits;  conditional E-value: 3.9e-29
     DUF3844   1 CfeseeacekatnsCsghGecvkklkskeegeacfvCkCeatvekkkedkkkttkwgGeaCekkDvsvefvllalttvalvvlvilsislLfsvGeeeL 99 
                 C++++++c+++tn CsghG c+ k++   + ++c++CkC               +wgG+aC+k D+s++f+l+ +++v+ +++v  +i+lLfsvG+eeL
  EEA22267.1 291 CHSTNDTCTSSTNACSGHGVCYLKSAGV-KDNDCYACKCD-------------SEWGGPACQKVDISTQFFLIGTVSVLAILAVGGGIGLLFSVGQEEL 375
                 9***********************9874.579*******9.............47******************************************** PP

     DUF3844 100 pgvlga 105
                 p+v++a
  EEA22267.1 376 PSVISA 381
                 ****97 PP

>> EGF_2  EGF-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5  10.3   5.9e-06     0.035       1      32 []     298     337 ..     298     337 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 5.9e-06
       EGF_2   1 CsasdeiCgghGtC.vnqcG.......qCdCdsgyqGktC 32 
                 C +s ++C+ghG+C  ++ G        C+Cds + G+ C
  EEA22267.1 298 CTSSTNACSGHGVCyLKSAGvkdndcyACKCDSEWGGPAC 337
                 7777899*******77777998887777***********9 PP

>> EGF_alliinase  Alliinase EGF-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       1.1   6.4e+03      25      40 ..     133     149 ..     131     164 .. 0.58
   2 ?   13.5   8.7   1.2e-05     0.075      15      50 ..     302     339 ..     292     343 .. 0.83

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 1.1
  EGF_alliinase  25 flDglvldg.kpvCECn 40 
                    f+D++++d  +    C+
     EEA22267.1 133 FVDSILMDTiSEWKHCE 149
                    88998877643322333 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 1.2e-05
  EGF_alliinase  15 aisCSGhGraflDglvldg..kpvCECnsCyaGkdCsq 50 
                    +  CSGhG  +l + ++++    +C C+s + G+ C +
     EEA22267.1 302 TNACSGHGVCYLKSAGVKDndCYACKCDSEWGGPACQK 339
                    568************976534679************76 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (390 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       745  (0.0415528); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2747.94
//
Query:       EEA22268.1  [L=415]
Description: RING finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.7e-13   48.2   6.4    1.5e-12   47.6   6.4    1.3  1  zf-RING_2     Ring finger domain
    7.4e-09   35.3   6.0    1.2e-08   34.7   6.0    1.3  1  zf-C3HC4_2    Zinc finger, C3HC4 type (RING finger)
    2.7e-08   33.4   0.9    4.5e-08   32.7   0.9    1.4  1  zf-RING_11    RING-like zinc finger
    3.5e-08   33.2   3.6    5.7e-08   32.5   3.6    1.4  1  zf-C3HC4      Zinc finger, C3HC4 type (RING finger)
    1.2e-06   28.4   3.1    1.9e-06   27.7   3.1    1.3  1  zf-RING_5     zinc-RING finger domain
    4.1e-06   27.0   9.8      2e-05   24.8   9.8    2.0  1  zf-rbx1       RING-H2 zinc finger domain
    3.1e-05   23.9   0.9    3.1e-05   23.9   0.9    2.2  2  zf-RING_UBOX  RING-type zinc-finger
    0.00089   19.1   2.4     0.0015   18.4   2.4    1.3  1  zf-C3HC4_3    Zinc finger, C3HC4 type (RING finger)
     0.0014   18.6   2.8      0.004   17.2   2.8    1.7  1  zf-ANAPC11    Anaphase-promoting complex subunit 11 RING-H2 f
  ------ inclusion threshold ------
      0.011   15.4   3.1      0.018   14.7   3.1    1.3  1  Zn_ribbon_17  Zinc-ribbon, C4HC2 type
      0.037   13.8   6.1      0.062   13.1   6.1    1.3  1  zf-RING_4     RING/Ubox like zinc-binding domain
      0.038   14.6   0.1        0.6   10.7   0.0    2.5  2  OAD_gamma     Oxaloacetate decarboxylase, gamma chain
      0.053   13.4   5.4       0.11   12.5   5.4    1.5  1  PHD           PHD-finger
      0.065   13.4   4.6       0.13   12.4   4.6    1.6  1  zf-C3HC4_4    zinc finger of C3HC4-type, RING
      0.091   12.6   4.9        0.2   11.5   4.9    1.6  1  Prok-RING_4   Prokaryotic RING finger family 4
       0.11   12.6   3.8       0.32   11.2   3.8    1.8  1  FANCL_C       FANCL C-terminal domain
       0.17   12.0   3.8       0.37   11.0   3.8    1.6  1  RINGv         RING-variant domain
          9    6.3   9.7       0.12   12.3   0.7    2.3  3  Prok-RING_1   Prokaryotic RING finger family 1


Domain annotation for each model (and alignments):
>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.6   6.4   1.5e-15   1.5e-12       1      44 []     237     281 ..     237     281 .. 0.95

  Alignments for each domain:
  == domain 1  score: 47.6 bits;  conditional E-value: 1.5e-15
   zf-RING_2   1 deCpICleelssadsvlllpCgHvfhreClerwlrssst.CPlCr 44 
                 d+C+ICl+ ++++d+v+ l CgH fh +Cl+ wl+s++  CPlC+
  EEA22268.1 237 DSCAICLDLIEDDDDVRGLTCGHAFHASCLDPWLTSRRAcCPLCK 281
                 58***************999**************99999*****7 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.7   6.0   1.2e-11   1.2e-08       2      40 .]     239     280 ..     238     280 .. 0.95

  Alignments for each domain:
  == domain 1  score: 34.7 bits;  conditional E-value: 1.2e-11
  zf-C3HC4_2   2 CpiCldmlkdpsvvt..pCgHvfCqkCilrsLeekn.eCPlC 40 
                 C+iCld ++d  +v    CgH f+++C++++L++    CPlC
  EEA22268.1 239 CAICLDLIEDDDDVRglTCGHAFHASCLDPWLTSRRaCCPLC 280
                 **********9999888*****************9999**** PP

>> zf-RING_11  RING-like zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.7   0.9   4.5e-11   4.5e-08       2      29 .]     239     266 ..     238     266 .. 0.98

  Alignments for each domain:
  == domain 1  score: 32.7 bits;  conditional E-value: 4.5e-11
  zf-RING_11   2 CsICLeefkpgqalfilpCsHtFHfkCI 29 
                 C+ICL+ +++++ ++ l C+H+FH  C+
  EEA22268.1 239 CAICLDLIEDDDDVRGLTCGHAFHASCL 266
                 ***************************5 PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.5   3.6   5.7e-11   5.7e-08       1      41 []     239     280 ..     239     280 .. 0.96

  Alignments for each domain:
  == domain 1  score: 32.5 bits;  conditional E-value: 5.7e-11
                 -TTT-S--SS-E...E-TTS--B-CHHHHHHHHCTSSB--TTT CS
    zf-C3HC4   1 CpiCleeakepn..elleCkHsfCskCirkilksrkkvkCPlC 41 
                 C+iCl+ +++ +  + l+C+H+f+ +C++ +l  ++  +CPlC
  EEA22268.1 239 CAICLDLIEDDDdvRGLTCGHAFHASCLDPWLT-SRRACCPLC 280
                 **********999999*****************.88899**** PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.7   3.1   1.9e-09   1.9e-06       2      43 ..     239     281 ..     238     282 .. 0.96

  Alignments for each domain:
  == domain 1  score: 27.7 bits;  conditional E-value: 1.9e-09
   zf-RING_5   2 CnkCfeklskeekfyltsCgHifCekClkkll.ekeavCpiCr 43 
                 C +C + +++++++  ++CgH f+ +Cl+  l  ++a+Cp+C+
  EEA22268.1 239 CAICLDLIEDDDDVRGLTCGHAFHASCLDPWLtSRRACCPLCK 281
                 ******************************9999********8 PP

>> zf-rbx1  RING-H2 zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.8   9.8     2e-08     2e-05      31      55 .]     256     281 ..     237     281 .. 0.74

  Alignments for each domain:
  == domain 1  score: 24.8 bits;  conditional E-value: 2e-08
     zf-rbx1  31 eCgHaFHlhCiskWlkt.rkvCPlcr 55 
                 +CgHaFH  C++ Wl++ r+ CPlc+
  EEA22268.1 256 TCGHAFHASCLDPWLTSrRACCPLCK 281
                 7***************956669***6 PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.9   3.1e-08   3.1e-05       1      35 [.     239     273 ..     239     276 .. 0.75
   2 ?   -0.4   0.9       1.2   1.2e+03       1      11 [.     277     287 ..     277     291 .. 0.76

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 3.1e-08
  zf-RING_UBOX   1 CpIClelftdP..lv.lpCGHtFCreCl..welskslega 35 
                   C ICl+l +d   +  l+CGH F+ +Cl  w     l  +
    EEA22268.1 239 CAICLDLIEDDddVRgLTCGHAFHASCLdpW-----LTSR 273
                   ********9444557778**********544.....4444 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 1.2
  zf-RING_UBOX   1 CpIClelftdP 11 
                   Cp C+ ++  P
    EEA22268.1 277 CPLCKADYYIP 287
                   *****777666 PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   2.4   1.5e-06    0.0015       4      46 ..     238     283 ..     236     285 .. 0.89

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 1.5e-06
                 B-TTTSS...SBS-EEETTEEEEEE-HHHHHHHHH.TT-B-TTT--B CS
  zf-C3HC4_3   4 eCviCle...rprnvvllpCgHlvlCeeCaekllk.rkkkCpiCrrp 46 
                  C iCl+    + +v  l CgH  +  +C++ +l  r++ Cp+C+++
  EEA22268.1 238 SCAICLDlieDDDDVRGLTCGHA-FHASCLDPWLTsRRACCPLCKAD 283
                 7******6545888*********.*********999********986 PP

>> zf-ANAPC11  Anaphase-promoting complex subunit 11 RING-H2 finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   2.8     4e-06     0.004      41      83 ..     235     286 ..     222     288 .. 0.69

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 4e-06
                 TTTTS-E..........EEBT.TS-EEEHHHHHHHHHHHSTSSB-TTTSSB--B CS
  zf-ANAPC11  41 pGddcpl..........vlGk.ckhnfhlhcilkwletetskglcpmcrqtfkl 83 
                 pGd c++          v G  c h+fh+ c+  wl ++  +  cp+c+  +++
  EEA22268.1 235 PGDSCAIcldlieddddVRGLtCGHAFHASCLDPWLTSR--RACCPLCKADYYI 286
                 5555555222111111144656**************865..689****998875 PP

>> Zn_ribbon_17  Zinc-ribbon, C4HC2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   3.1   1.8e-05     0.018       6      46 ..     238     278 ..     233     281 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.8e-05
  Zn_ribbon_17   6 sCayC.elavkgrvvlcgvCeHvlHasCarewfenddlaeCp 46 
                   sCa+C +l      v    C+H  HasC++ w++    a Cp
    EEA22268.1 238 SCAIClDLIEDDDDVRGLTCGHAFHASCLDPWLTSRR-ACCP 278
                   7888833444455677789**************9998.7776 PP

>> zf-RING_4  RING/Ubox like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   6.1   6.2e-05     0.062       1      47 [.     239     284 ..     239     285 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 6.2e-05
   zf-RING_4   1 cplCdeeldetdkdlkpCeCgyqiClfCyhrileeeegrCPaCreeY 47 
                 c +C + + e+d+d++  +Cg+ +   C++  l++  ++CP C+ +Y
  EEA22268.1 239 CAICLDLI-EDDDDVRGLTCGHAFHASCLDPWLTSRRACCPLCKADY 284
                 78888877.5677889999**************************99 PP

>> OAD_gamma  Oxaloacetate decarboxylase, gamma chain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0    0.0006       0.6       8      40 ..      39      71 ..      35      98 .. 0.81
   2 ?    0.4   0.3         1     1e+03      35      62 ..     192     221 ..     180     229 .. 0.49

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.0006
   OAD_gamma  8 llGmgvVFvvLilLslvislfskiikkkakkkk 40
                 lG+gvVF+ L +++ v ++f++  +  + +++
  EEA22268.1 39 ALGFGVVFTNLWIIVGVKYCFRYNQRNRQLRNE 71
                69******************9987766655555 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 1
   OAD_gamma  35 kakkkkkkakaaaaaaaaaaaaa..elddd 62 
                  + ++k + ++aa+++ ++ +++  ++ dd
  EEA22268.1 192 TEVQPKTATTEAASNVHPPHEEEmhDENDD 221
                 333333333333333333333335544444 PP

>> PHD  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   5.4   0.00011      0.11       2      51 ..     239     282 ..     238     283 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00011
                 BTTTTSTTSTTSCEEEETTTSCEEETTTSSSTHSHHSHHSSTBSSTTTHT CS
         PHD   2 CavCkkksdeeeelvqCdgCkrwfHqkClkppleseekpegewlCekCke 51 
                 Ca+C +   e+++ v   +C+++fH +Cl+p l+s++      +C+ Ck 
  EEA22268.1 239 CAICLD-LIEDDDDVRGLTCGHAFHASCLDPWLTSRRA-----CCPLCKA 282
                 9*****.888899999999*************995544.....8999985 PP

>> zf-C3HC4_4  zinc finger of C3HC4-type, RING
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   4.6   0.00013      0.13       1      42 []     239     280 ..     239     280 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00013
  zf-C3HC4_4   1 CPiCldYLekP...vsleCGhsfClsCisslqkepdgeqllCplC 42 
                 C iCld++e+      l CGh f  sC++ +  +  +    CplC
  EEA22268.1 239 CAICLDLIEDDddvRGLTCGHAFHASCLDPWLTSRRA---CCPLC 280
                 99******9762224589*************999976...6**99 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   4.9    0.0002       0.2       7      38 ..     248     282 ..     238     285 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.0002
  Prok-RING_4   7 qekkailepCgHlvCkeCfdskdls...sCPlCqr 38 
                   + +++   CgH +  +C+d +  s    CPlC+ 
   EEA22268.1 248 DDDDVRGLTCGHAFHASCLDPWLTSrraCCPLCKA 282
                  366777789*************8777889****85 PP

>> FANCL_C  FANCL C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   3.8   0.00032      0.32       4      45 ..     238     274 ..     236     284 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00032
                 S-SSS--SS-TT-----B--S-TT----B-SGGGHHHHHHHH CS
     FANCL_C   4 eCgiCyayrldsgevpdisCdnekCnkkfHsaCLkeWlrslk 45 
                 +C iC+    d++ v   +     C++ fH++CL  Wl s +
  EEA22268.1 238 SCAICLDLIEDDDDVRGLT-----CGHAFHASCLDPWLTSRR 274
                 6888887777777776655.....7899**********9875 PP

>> RINGv  RING-variant domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   3.8   0.00037      0.37       1      48 []     239     280 ..     239     280 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00037
                 ETTTTEE-SSSS--B-SS--STCCCSB-HHHHHHHHHHTCT-SB-TTT CS
       RINGv   1 CriCleeeeeseplispCkCrGslklvHesClekWldekeantqCeiC 48 
                 C iCl+  e+++  ++   C    + +H sCl+ Wl++  +   C +C
  EEA22268.1 239 CAICLDLIEDDD-DVRGLTCG---HAFHASCLDPWLTS--RRACCPLC 280
                 556666554444.23444443...689**********9..8899*999 PP

>> Prok-RING_1  Prokaryotic RING finger family 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       8.5   8.5e+03      28      40 ..     150     162 ..     149     170 .. 0.83
   2 ?   12.3   0.7   0.00012      0.12       4      35 ..     236     266 ..     234     269 .. 0.89
   3 ?   -1.6   1.0       2.7   2.7e+03      23      30 ..     277     284 ..     274     285 .. 0.74

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 8.5
  Prok-RING_1  28 tpyHraCyekagk 40 
                  t +H + y  +g+
   EEA22268.1 150 TAHHVEAYAPKGH 162
                  8899999988887 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 0.00012
  Prok-RING_1   4 gkkCpvCgkelkeedDiVvCpeCgtpyHraCy 35 
                  g++C +C + ++++dD V   +Cg  +H +C 
   EEA22268.1 236 GDSCAICLDLIEDDDD-VRGLTCGHAFHASCL 266
                  689******9999987.78899*********6 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 2.7
  Prok-RING_1  23 CpeCgtpy 30 
                  Cp C++ y
   EEA22268.1 277 CPLCKADY 284
                  88888766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (415 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       805  (0.0448993); expected 358.6 (0.02)
Passed bias filter:                      508  (0.028334); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              18  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 2662.39
//
Query:       EEA22269.1  [L=178]
Description: peptidyl-prolyl cis-trans isomerase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.8e-51  172.9   0.9    6.7e-51  172.7   0.9    1.0  1  Pro_isomerase  Cyclophilin type peptidyl-prolyl cis-trans iso


Domain annotation for each model (and alignments):
>> Pro_isomerase  Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  172.7   0.9   3.8e-55   6.7e-51       3     157 ..      16     176 ..      14     177 .. 0.89

  Alignments for each domain:
  == domain 1  score: 172.7 bits;  conditional E-value: 3.8e-55
  Pro_isomerase   3 dietss..kGrivieLfadkaPktvenFlklvkeg..........fYdgttFhRvikgfmvqgGdptgktsageqekkggesiraipdEitsklkh 86 
                    di+ ++  +Gr+++eLfad +P t+enF++++ +g           Y+g++FhRvik+fm+qgGd+ +++ +g+++  gg   ++++dE+ ++lkh
     EEA22269.1  16 DIALGGepLGRVKMELFADVTPRTAENFRQFC-TGetknnlgrpqGYKGCKFHRVIKDFMIQGGDFINGDGTGSASIYGG---QKFADEN-FNLKH 106
                    666655668***********************.566888999999********************999877666554444...48*****.67777 PP

  Pro_isomerase  87 .krGalamartgkepnsagsqFfItlkeaphldgkytvFGkVveGmdvvekiekvetdeerpkknvkivsae 157
                     k+G+l+ma++g  pn++g+qFfIt+ ++p+l++k++vFG+VveGmd+v  ie+++t +++p+++v+i++++
     EEA22269.1 107 nKEGLLSMANSG--PNTNGCQFFITTVPTPFLNNKHVVFGQVVEGMDIVHMIENTRTTRDKPNQDVTIIQCG 176
                    699********8..8*******************************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (178 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       274  (0.0152825); expected 358.6 (0.02)
Passed bias filter:                      244  (0.0136092); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.24s 00:00:00.63 Elapsed: 00:00:00.40
# Mc/sec: 1345.51
//
Query:       EEA22270.1  [L=1000]
Description: alanyl-tRNA synthetase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   1.6e-221  736.7   0.0   2.7e-221  735.9   0.0    1.4  1  tRNA-synt_2c  tRNA synthetases class II (A)
    2.8e-16   59.3   0.9    6.6e-16   58.1   0.9    1.7  1  tRNA_SAD      Threonyl and Alanyl tRNA synthetase second addi
    6.6e-12   46.0   0.6    6.6e-12   46.0   0.6    2.4  2  DHHA1         DHHA1 domain


Domain annotation for each model (and alignments):
>> tRNA-synt_2c  tRNA synthetases class II (A)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  735.9   0.0  4.5e-225  2.7e-221       2     551 ..      55     634 ..      54     635 .. 0.95

  Alignments for each domain:
  == domain 1  score: 735.9 bits;  conditional E-value: 4.5e-225
                   HHHHHHHHHHCTT-EEE----SS-SSSTTCSS--SGGGGGHHHHTTSS....CGGSSSEEEEEEEEE-EETTEEGGGGTTTSSS--SEEEEEEEEES CS
  tRNA-synt_2c   2 irekFldfFekkgHtvvksssvvpendptllfvnAgmaqfkpiflgke....akpklkravnsQkciRagGkhnDlenVGktarHhTfFeMlGnfsf 94 
                   +r++F+d+F+++gHt+v+sssvvp  dptllf+nAgm+q+k iflg++    + ++lkravnsQkciRagGkhnDl++VGk+++HhTfFeMlGn+sf
    EEA22270.1  55 VRNEFIDYFKERGHTFVPSSSVVPVSDPTLLFANAGMNQYKSIFLGTVdpqsDFAHLKRAVNSQKCIRAGGKHNDLDDVGKDNYHHTFFEMLGNWSF 151
                   9***********************************************9998999****************************************** PP

                   SSS-HHHHHHHHHHHHHTTTT--GGGEEEEEETTEH........HHHHHHHHTTTTEGGGEEEE-HHHHEEESSSSEEEEEEEEEEEECETTSHHCH CS
  tRNA-synt_2c  95 gdYfkeeaiefawelltkelgldkerlyvtvfeedd........eaveiweklvgvpeerilrfgekdnfwemgdtgpcgpcseiyydrgeeigkrk 183
                   gdYfk+eai+++welltk++gld++rlyvt+fe+d         ea++iw+k++ vpe++il+ ++kdnfwemgd+gpcgpcse++ydr   ig+r+
    EEA22270.1 152 GDYFKNEAITYSWELLTKVFGLDPSRLYVTYFEGDAqgglepdlEAKDIWRKVG-VPEDHILPGNMKDNFWEMGDQGPCGPCSEVHYDR---IGGRN 244
                   ***********************************99****************6.**********************************...***** PP

                   CCCCTTCTCCHEEEEEEEEEEEEEESTTSHEEEEEEEEEEEEEEHHHHHHHHTTHSSGGGSCCTHHHHHHHHHHHT-.-T......CSTCCHHHHHH CS
  tRNA-synt_2c 184 aaseveadddrvleiwnlvfmqfnreedgtlkpLpkksidtGmglerlvavLqevrsnydtdlfvpvieaieeisga.ty......edkdetdealr 273
                   aas v++dd++vleiwn vf+q+nre+d++l+pLp+k++dtGmg+erlv+vLq++ snydtd+f+p++ +i+ei+ga +y      ed+d++d+a+r
    EEA22270.1 245 AASLVNQDDPNVLEIWNNVFIQYNREADRSLRPLPNKHVDTGMGFERLVSVLQDKSSNYDTDVFMPLFRTIQEITGArEYqgrfgaEDADGVDTAYR 341
                   ****************************************************************************9899***************** PP

                   HHHHHHHHHHHHHHTT--SSSSHHHHHHHHHHHHHHHHH.HHTT-SST.HHHHHHHHHHHHHTTTGCCHHCCHHHHHHHHHHHHHHHHCCHHHHHHH CS
  tRNA-synt_2c 274 viaDHvralafaladGvvpsnegrgYvlRrllRravrha.kkLglkek.flaklvavvvevlgdvypelkekeekveeiieeEeerFakTlerGlkl 368
                   v+aDHvr+l+fa++dG+ p+negrgYv+Rr+lRr+ r+a k ++++ + f++k+v+++v+++g ++pe+kek+++v+e+++eEe +F+kTl+rG+k 
    EEA22270.1 342 VVADHVRTLTFAISDGAYPNNEGRGYVIRRVLRRGARYArKYFNVEIGsFFSKIVPTLVNQMGGMFPEIKEKQDEVMEALNEEEVSFSKTLDRGEKQ 438
                   ***************************************999****988************************************************ PP

                   HHHHHHHCCC..CSEEXHHHHHHHHHCHXXXHHHHHHHHHCTTXEEXHHHHHHHHHHHHHHHCCHHSXSS.XXXXXXXXTTSHCHH......CCTST CS
  tRNA-synt_2c 369 leelikklkk..kkelsgedafkLydtyGfPvdltkeiaeekglkvdiegfekameeqrerskkekkekk.likkdvealkelkkt......eeflg 456
                   +e++++++k+   ++l+g+d+++Lydt+GfPvdlt+ +aee+gl++d+ +fe+a+ +++e sk +kk+ + ++k dv++l +l+++      +++ +
    EEA22270.1 439 FENYAQQAKSkgLNKLHGADVWRLYDTFGFPVDLTQIMAEERGLSIDEAEFEEARLKAKEASKGQKKAAAeTVKLDVHDLGKLDNMhevpktDDSSK 535
                   *******9987889************************************************97776666699999999888888756666678888 PP

                   TTXXXXXXTSXXXXXXSEEEE...EEEEEETTEEEESEEXXXXSSSSCSXXXEEEEESS.EEEEESEEEEETTEEEEEXSS.XSXXXTTSEEEEEEX CS
  tRNA-synt_2c 457 yeeleaeakvlallkdkefve...eveegeevgvvLdrTpfYaesGGqigDeGliekeg.aefrvkdvqkakgvvlhkgkleegklkvgdkvkaevd 549
                   +++ ++e+ v a++ +k+f +   +v ege+ gv+LdrT+fYae+GGq++D+G+i  +g ae++v dvq ++g+vlh+g +++g+l vgd+v++e+d
    EEA22270.1 536 FDSPKIESVVKAIYYSKSFIQttaDVPEGEQIGVILDRTNFYAEQGGQENDTGAIYINGkAELEVGDVQSYGGYVLHTGFIKYGSLAVGDSVTCEFD 632
                   8888**********9998876111566799999********************66544438************************************ PP

                   HH CS
  tRNA-synt_2c 550 ee 551
                   ++
    EEA22270.1 633 DR 634
                   86 PP

>> tRNA_SAD  Threonyl and Alanyl tRNA synthetase second additional domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.1   0.9   1.1e-19   6.6e-16       1      43 [.     733     791 ..     733     792 .. 0.96

  Alignments for each domain:
  == domain 1  score: 58.1 bits;  conditional E-value: 1.1e-19
                 EEEEEETT.................EEEEESS---SBGGGC-SEEEECCECCCTCEEEE CS
    tRNA_SAD   1 vrvvsiGd................isvelCgGtHvpnTgeIgafkilseesiakglrRI 43 
                 vrvvs+G                 is+e+CgGtHv++ geI++ +il+e++iakg+rRI
  EEA22270.1 733 VRVVSVGVeveeilkdvkdprwndISIEFCGGTHVSKSGEIRELVILEESGIAKGIRRI 791
                 8******66889999*******************************************9 PP

>> DHHA1  DHHA1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1      0.47   2.8e+03      15      44 ..     484     508 ..     478     532 .. 0.61
   2 !   46.0   0.6   1.1e-15   6.6e-12      15     137 ..     860     994 ..     846     995 .. 0.82

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.47
                 HHCHHHHHHHHHHHHHHHTCEEECTCEEEE CS
       DHHA1  15 leelkealaklkaeellekaeevkgvkvlv 44 
                 ++e++ ++a+lka+e+ +  ++      ++
  EEA22270.1 484 IDEAEFEEARLKAKEASKGQKK-----AAA 508
                 5666777777777777665332.....222 PP

  == domain 2  score: 46.0 bits;  conditional E-value: 1.1e-15
                 HHCHHHHHHHHHHHHHHHTCEEEC......TCEEEEEECHCCHHHHHHHHHHHHHHTHGBTTCEEEEEEEECT.EEEEEEEESSH....SS-HHHHHHH CS
       DHHA1  15 leelkealaklkaeellekaeevk......gvkvlvaevgeewdagalgiaadklksklkkpvivfvakeegd.kvkvsarskkd....gvdagelake 102
                 + + ++a +k++ +++++ ++ +       g +++va++ ++ + +++ + ++ +ksk+ ++++ f+a +    kv+  + ++k+    g++ + +a+ 
  EEA22270.1 860 VLDDQKAQQKVELKKAQDLIKAYFdaeenkGRSTFVAKLPATSNSKVVSESINFIKSKMADKTVYFFAPDPSGnKVAHGCHVSKAasdlGLSPSGWANV 958
                 444444444444444444433333444667*******************************9999999999999*********99************** PP

                 HHHHTTCCEEEE.TCEEEEEEEHCHHHHHHHHHHHH CS
       DHHA1 103 aaaklgggGGGH.dlAaGagipaekleealealeea 137
                 ++ ++gg+ GG+ + A G g++++k++e ++++ e+
  EEA22270.1 959 VSGAVGGKAGGKaPTAIGNGTNPDKVDEGVALATEY 994
                 ****************************99998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1000 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       977  (0.0544927); expected 358.6 (0.02)
Passed bias filter:                      547  (0.0305092); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.75u 0.27s 00:00:01.02 Elapsed: 00:00:00.41
# Mc/sec: 7295.68
//
Query:       EEA22271.1  [L=183]
Description: hypothetical protein PMAA_060500 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (183 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       557  (0.031067); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.39u 0.27s 00:00:00.66 Elapsed: 00:00:00.42
# Mc/sec: 1319.91
//
Query:       EEA22272.1  [L=270]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.1e-35  122.5   6.5    2.1e-35  122.5   6.5    2.0  2  DUF3752      Protein of unknown function (DUF3752)
  ------ inclusion threshold ------
      0.015   14.6   0.6      0.015   14.6   0.6    1.7  2  Dynamitin    Dynamitin


Domain annotation for each model (and alignments):
>> DUF3752  Protein of unknown function (DUF3752)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   2.1      0.46   4.1e+03     107     116 ..      55      64 ..      17     112 .. 0.63
   2 !  122.5   6.5   2.3e-39   2.1e-35       1     152 []     117     265 ..     117     265 .. 0.95

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.46
     DUF3752 107 kkeeeeddps 116
                 ++ +e+dd+s
  EEA22272.1  55 QEPQESDDSS 64 
                 1122223222 PP

  == domain 2  score: 122.5 bits;  conditional E-value: 2.3e-39
     DUF3752   1 PPessdlssrvdptklknrkFatgkaakaa...agdsslWteTPeekakrladevlgrkekaaaaaaakeakekkreeeetaekvkeynekkRgksLve 96 
                 PPe+s+++s  +p  l+nrkF +gk+a+++   +g  s+Wte P++k++rl++evlg+k++++a++a+++ + + r+++ ta+k+k+ + k  ++sL+e
  EEA22272.1 117 PPENSSWASGPNPAALTNRKFMSGKSARGTrstDGAGSVWTEDPAQKRQRLENEVLGIKSESSARSARSR-DLSYRTNSSTADKLKSLTGKVGKSSLYE 214
                 9***********************8888888889******************************999997.66667779******************** PP

     DUF3752  97 ehqekkkkkkkkeeeeddpskraFDrekDmalgrriskaqrkellkkaadfgsRFs 152
                 +hq++ +k      +eddps+raFD ekD+a++++is+ +r++ll++a+d+ sRFs
  EEA22272.1 215 THQKDIQK-----PKEDDPSRRAFDYEKDVAGKTSISSGARRKLLNQASDYTSRFS 265
                 ******99.....69****************************************7 PP

>> Dynamitin  Dynamitin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.3     0.094   8.4e+02      45      86 ..      51      98 ..      16     110 .. 0.51
   2 ?   14.6   0.6   1.7e-06     0.015      78     162 ..     144     225 ..     132     260 .. 0.72

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.094
   Dynamitin 45 ArskFkgkkvd.akgvDFs......driskkertgykasssreyelade 86
                ++sk ++++ d +++ DF          +k++ ++y+++s+ + +++d+
  EEA22272.1 51 SESKQEPQESDdSSDDDFGpqlppvGG-TKSSPSKYEVESRPTPRINDG 98
                444444444444555555534433211.222455555555555555444 PP

  == domain 2  score: 14.6 bits;  conditional E-value: 1.7e-06
   Dynamitin  78 sreyeladege.eketleqklqRLqrEveeleeEvekakeaakeseeeeldpvelaeqleslqkqLeeleellgedsaasltdaqe 162
                 ++++++ + g+  +e ++qk qRL  Ev  +++E +++++ + +   +  +++  a++l+sl  ++ +  +l +++++   ++++e
  EEA22272.1 144 RGTRSTDGAGSvWTEDPAQKRQRLENEVLGIKSESSARSARSRD--LSYRTNSSTADKLKSLTGKVGKS-SLYETHQKD-IQKPKE 225
                 45555555555789***********************9999885..44555667899*****9999999.444444444.333322 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (270 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       483  (0.0269396); expected 358.6 (0.02)
Passed bias filter:                      197  (0.0109878); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.43
# Mc/sec: 1884.78
//
Query:       EEA22273.1  [L=254]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.7e-35  122.8   6.5    1.7e-35  122.8   6.5    2.0  2  DUF3752    Protein of unknown function (DUF3752)
  ------ inclusion threshold ------
      0.013   14.8   0.6      0.013   14.8   0.6    1.7  2  Dynamitin  Dynamitin


Domain annotation for each model (and alignments):
>> DUF3752  Protein of unknown function (DUF3752)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   2.0      0.48   4.3e+03     108     116 ..      40      48 ..       8      96 .. 0.63
   2 !  122.8   6.5   1.9e-39   1.7e-35       1     152 []     101     249 ..     101     249 .. 0.95

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.48
     DUF3752 108 keeeeddps 116
                 + +e+dd+s
  EEA22273.1  40 EPQESDDSS 48 
                 122333332 PP

  == domain 2  score: 122.8 bits;  conditional E-value: 1.9e-39
     DUF3752   1 PPessdlssrvdptklknrkFatgkaakaa...agdsslWteTPeekakrladevlgrkekaaaaaaakeakekkreeeetaekvkeynekkRgksLve 96 
                 PPe+s+++s  +p  l+nrkF +gk+a+++   +g  s+Wte P++k++rl++evlg+k++++a++a+++ + + r+++ ta+k+k+ + k  ++sL+e
  EEA22273.1 101 PPENSSWASGPNPAALTNRKFMSGKSARGTrstDGAGSVWTEDPAQKRQRLENEVLGIKSESSARSARSR-DLSYRTNSSTADKLKSLTGKVGKSSLYE 198
                 9***********************8888888889******************************999997.66667779******************** PP

     DUF3752  97 ehqekkkkkkkkeeeeddpskraFDrekDmalgrriskaqrkellkkaadfgsRFs 152
                 +hq++ +k      +eddps+raFD ekD+a++++is+ +r++ll++a+d+ sRFs
  EEA22273.1 199 THQKDIQK-----PKEDDPSRRAFDYEKDVAGKTSISSGARRKLLNQASDYTSRFS 249
                 ******99.....69****************************************7 PP

>> Dynamitin  Dynamitin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.2     0.097   8.7e+02      45     200 ..      35      76 ..       5      94 .. 0.50
   2 ?   14.8   0.6   1.5e-06     0.013      78     162 ..     128     209 ..     116     244 .. 0.72

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.097
   Dynamitin  45 ArskFkgkkvd.akgvDFsdriskkertgykasssreyeladegeeketleqklqRLqrEveeleeEvekakeaakeseeeeldpvelaeqleslqkqL 142
                 ++sk ++++ d +++ DF                                                                                 
  EEA22273.1  35 SESKQEPQESDdSSDDDFG-------------------------------------------------------------------------------- 53 
                 3333333333334444444................................................................................ PP

   Dynamitin 143 eeleellgedsaasltdaqealakrllsqleefkeskaaskkk.......eksnkityelyyape 200
                                                                   +ks+  +ye+ ++p+
  EEA22273.1  54 ------------------------------------------PqlppvggTKSSPSKYEVESRPT 76 
                 ..........................................03333333333333344333333 PP

  == domain 2  score: 14.8 bits;  conditional E-value: 1.5e-06
   Dynamitin  78 sreyeladege.eketleqklqRLqrEveeleeEvekakeaakeseeeeldpvelaeqleslqkqLeeleellgedsaasltdaqe 162
                 ++++++ + g+  +e ++qk qRL  Ev  +++E +++++ + +   +  +++  a++l+sl  ++ +  +l +++++   ++++e
  EEA22273.1 128 RGTRSTDGAGSvWTEDPAQKRQRLENEVLGIKSESSARSARSRD--LSYRTNSSTADKLKSLTGKVGKS-SLYETHQKD-IQKPKE 209
                 45555555555789***********************9999885..44555667899*****9999999.444444444.333322 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (254 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       640  (0.0356964); expected 358.6 (0.02)
Passed bias filter:                      272  (0.015171); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.23s 00:00:00.67 Elapsed: 00:00:00.40
# Mc/sec: 1924.83
//
Query:       EEA22274.1  [L=370]
Description: hypothetical protein PMAA_060540 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-13   50.9   0.0    1.8e-13   50.5   0.0    1.1  1  RVT_1     Reverse transcriptase (RNA-dependent DNA polymerase
    9.3e-07   29.1   0.0      2e-06   28.0   0.0    1.6  1  RNase_H   RNase H
    1.7e-05   25.4   0.0    3.3e-05   24.5   0.0    1.4  1  zf-RVT    zinc-binding in reverse transcriptase


Domain annotation for each model (and alignments):
>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.5   0.0   3.1e-17   1.8e-13     109     210 ..       1     116 [.       1     147 [. 0.86

  Alignments for each domain:
  == domain 1  score: 50.5 bits;  conditional E-value: 3.1e-17
                 ...............TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T......TEEECTTEEEEEESSHHH......HHHHHHHHHHHHHHTT--BEGG CS
       RVT_1 109 lstrsfsvrvngeeskgryekkglpqGsvlSPllfnlfmnellrelrkrakgvtllrYaDDililskskee......lqelleaveewlkesglkinpe 201
                 +s+r++ + ++g+  ++ +++ glpqGs++SP+lf l++  l   l+++++gv  l ++DD  +++   +       lq++ ++  ew  e+g+++ p+
  EEA22274.1   1 MSNRRAMLVIDGHVGEEVPISSGLPQGSPVSPILFVLYVRLLATALESAVPGVRGLSFVDDQGLVTAASSIkeacktLQHAAKVAIEWGVENGVQFDPS 99 
                 5899999999***66**********************************************7665555444458************************* PP

                 G-EEE............ CS
       RVT_1 202 Ktklvlft........v 210
                 Kt+++ ft        v
  EEA22274.1 100 KTEAAFFTrqlfdaelV 116
                 *****988666555550 PP

>> RNase_H  RNase H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.0   0.0   3.3e-10     2e-06      45     141 ..     112     200 ..      74     202 .. 0.73

  Alignments for each domain:
  == domain 1  score: 28.0 bits;  conditional E-value: 3.3e-10
                 HHHHHHHHHHHH.TT.SC..SEEEEEES-HHHHHHHHCCCHHHHHTTSSSETTSSBHTTHHHHHHHHHCHCSSEEEEEE-SCCSSSTHHHHHHHHHHHH CS
     RNase_H  45 raELsAvieaLk.alksd..ekvniytDSkYvvkgitqwvhrwkknawkttseqkpvknkdlaellkelakkkkvqlkwvkgHaGvpkgNemaDrlAke 140
                  aEL  v  aL+ al+++    +++  D ++++k +++   +  + +  ++ + +p +    a +l    + + v+++wv+gH+ v +gNe+aD++Ak 
  EEA22274.1 112 DAELVGVASALEwALERHlpGPIHVLLDAQNAIKRLQS---T--EPGAGQSLALRPHMT---ASRL--RLSGRPVTIQWVPGHNRV-EGNEQADQAAKP 199
                 59************9999878999********995555...2..223333444444444...4444..356899************.7*********96 PP

                 H CS
     RNase_H 141 a 141
                  
  EEA22274.1 200 T 200
                 5 PP

>> zf-RVT  zinc-binding in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.5   0.0   5.5e-09   3.3e-05      26      79 ..     235     288 ..     228     291 .. 0.93

  Alignments for each domain:
  == domain 1  score: 24.5 bits;  conditional E-value: 5.5e-09
      zf-RVT  26 skappkvkfflWlllknrlptadnllkrgiesssrCqlCgqeeEtieHlfleCp 79 
                 +kap +v    + l +++ p+   l++ ++  s++C  Cg+  Eti+H+++eC+
  EEA22274.1 235 AKAPKRVASRSYQLKTGHAPIGTYLHRIKARDSPECGACGELRETISHIIFECR 288
                 67888999999999999************************************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (370 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       284  (0.0158403); expected 358.6 (0.02)
Passed bias filter:                      261  (0.0145574); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.28s 00:00:00.79 Elapsed: 00:00:00.47
# Mc/sec: 2369.79
//
Query:       EEA22275.1  [L=433]
Description: transposon, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.7e-34  117.0   0.0    1.3e-33  116.1   0.0    1.5  1  DDE_1        DDE superfamily endonuclease
    1.8e-09   37.5   0.0    3.4e-09   36.6   0.0    1.5  1  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
    1.9e-06   27.5   0.0    3.9e-06   26.5   0.0    1.5  1  HTH_psq      helix-turn-helix, Psq domain


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.1   0.0   2.2e-37   1.3e-33       2     175 .]     204     373 ..     203     373 .. 0.96

  Alignments for each domain:
  == domain 1  score: 116.1 bits;  conditional E-value: 2.2e-37
       DDE_1   2 erltvllcanaagsekLkplvigkak.sprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrle..aekrkilLlldssrshetvel.les 95 
                 ++++++++a  +++  +++++i+kak + r  ++   ++ ++d+++++++++w+t++i+ eWL  +f++ ++  + +++ +L+ld+++sh t+e+   +
  EEA22275.1 204 REWVTAIEATNSTGWAIPSYIIFKAKkNVRLGWF---DDLPSDWRINISENGWTTDQIGLEWLkTHFIPYINgrSMGSYRMLILDGHGSHLTAEFdRTC 299
                 7899********************9725677888...99*********************************99*********************9*** PP

       DDE_1  96 elqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                  ++ni  +++P++s++llqPld+g+++ lK++Y +q+ q + ++ n+++k       ld+l    kA++ a + +ti+++f
  EEA22275.1 300 TENNIIPICMPPHSSHLLQPLDVGCFAVLKRHYGQQVEQRMRDGFNHIDK-------LDFLMAFPKARTeAYKARTIQNSF 373
                 **************************************************.......9**********9999999999987 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.6   0.0   5.7e-13   3.4e-09       2      61 ..      70     125 ..      69     130 .. 0.90

  Alignments for each domain:
  == domain 1  score: 36.6 bits;  conditional E-value: 5.7e-13
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT.S CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh.g 61 
                  + +E++L++W+ +l++rg p++++l+r++ + l+     l++++++++k+W+ + +kR  +
   EEA22275.1  70 QSEEDSLVKWVLDLDRRGLPPRHSLVRDMVNYLL-----LQHGKPQVGKNWVTNLIKRRpE 125
                  578*****************************95.....6679***************854 PP

>> HTH_psq  helix-turn-helix, Psq domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.5   0.0   6.5e-10   3.9e-06       2      41 ..      16      56 ..      15      59 .. 0.93

  Alignments for each domain:
  == domain 1  score: 26.5 bits;  conditional E-value: 6.5e-10
     HTH_psq  2 pealaaAleavvnGk.mSirkAArkYgiPrsTLwrrkrgky 41
                + ++++A+ +  nG  + ir+A r+Y+iPr+TL+ r++g++
  EEA22275.1 16 EGKIQLAISDLKNGRiLNIREATRIYDIPRTTLRDRLKGIE 56
                678999********************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (433 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       358  (0.0199677); expected 358.6 (0.02)
Passed bias filter:                      315  (0.0175693); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 2998.54
//
Query:       EEA22276.1  [L=62]
Description: hypothetical protein PMAA_060560 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (62 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2230  (0.124379); expected 358.6 (0.02)
Passed bias filter:                      753  (0.041999); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.42
# Mc/sec: 446.79
//
Query:       EEA22277.1  [L=423]
Description: hypothetical protein PMAA_060570 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-06   28.0   0.0    3.8e-06   27.1   0.0    1.5  1  RNase_H   RNase H
    2.1e-05   25.1   0.0      4e-05   24.2   0.0    1.3  1  zf-RVT    zinc-binding in reverse transcriptase


Domain annotation for each model (and alignments):
>> RNase_H  RNase H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.1   0.0   4.3e-10   3.8e-06      46     141 ..     166     253 ..     129     255 .. 0.77

  Alignments for each domain:
  == domain 1  score: 27.1 bits;  conditional E-value: 4.3e-10
                 HHHHHHHHHHH.TT.SC..SEEEEEES-HHHHHHHHCCCHHHHHTTSSSETTSSBHTTHHHHHHHHHCHCSSEEEEEE-SCCSSSTHHHHHHHHHHHHH CS
     RNase_H  46 aELsAvieaLk.alksd..ekvniytDSkYvvkgitqwvhrwkknawkttseqkpvknkdlaellkelakkkkvqlkwvkgHaGvpkgNemaDrlAkea 141
                 aEL  v  aL+ al+++    +++  D ++++k +++   +  + +  ++ + +p +    a +l    + + v+++wv+gH+ v +gNe+aD++Ak  
  EEA22277.1 166 AELVGVASALEwALERHlpGPIHVLLDAQNAIKRLQS---T--EPGAGQSLALRPHMT---ASRL--RLSGRPVTIQWVPGHNRV-EGNEQADQAAKPT 253
                 89*********999999878999*******9995555...2..223333444444444...3444..356889************.7*********965 PP

>> zf-RVT  zinc-binding in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.2   0.0   4.5e-09     4e-05      26      79 ..     288     341 ..     281     344 .. 0.93

  Alignments for each domain:
  == domain 1  score: 24.2 bits;  conditional E-value: 4.5e-09
      zf-RVT  26 skappkvkfflWlllknrlptadnllkrgiesssrCqlCgqeeEtieHlfleCp 79 
                 +kap +v    + l +++ p+   l++ ++  s++C  Cg+  Eti+H+++eC+
  EEA22277.1 288 AKAPKRVASRSYQLKTGHAPIGTYLHRIKARDSPECGACGELRETISHIIFECR 341
                 67888999999999999************************************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (423 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       318  (0.0177366); expected 358.6 (0.02)
Passed bias filter:                      290  (0.0161749); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.47
# Mc/sec: 2699.51
//
Query:       EEA22278.1  [L=725]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (725 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       490  (0.02733); expected 358.6 (0.02)
Passed bias filter:                      253  (0.0141112); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.62u 0.25s 00:00:00.87 Elapsed: 00:00:00.45
# Mc/sec: 4879.30
//
Query:       EEA22279.1  [L=1061]
Description: AMP deaminase Amd1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
   1.9e-123  412.0   0.0   2.8e-123  411.4   0.0    1.3  1  A_deaminase  Adenosine/AMP deaminase


Domain annotation for each model (and alignments):
>> A_deaminase  Adenosine/AMP deaminase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  411.4   0.0  1.6e-127  2.8e-123       1     327 [.     440     845 ..     440     846 .. 1.00

  Alignments for each domain:
  == domain 1  score: 411.4 bits;  conditional E-value: 1.6e-127
                  TS-EEEEEEECCCSS-HHHHHHHHHHHCHT..SS-SCCCCCCCCHCHCCHHHHCCHCCCHHCCCHHHT.............................. CS
  A_deaminase   1 nlpKvdlHvHldgclnpktllrlakkkgikeldekvveedeklltlqekfesLkeflydlsvdvlvlh.............................. 68 
                  n++Kvd+HvH+++c+n+k+llr++k+k++k++de+v+++d+++ltl+e+fes+++++ydls+d+l++h                              
   EEA22279.1 440 NVRKVDTHVHHSACMNQKHLLRFIKSKMKKSPDEVVLFRDGRHLTLKEVFESINLTAYDLSIDTLDMHahkdsfhrfdkfnlkynpvgesrlreiflk 537
                  89************************************************************************************************ PP

                  .............................................................CCCCCCHHHHHHCCCCCHCTTCCCCCCCCSHHHHHHH CS
  A_deaminase  69 .............................................................wlievvrllavekakdlakdfvkylevifsPlfeata 105
                                                                               wli+v+rl++v+k+++++++f+++++++f+Plfe+t 
   EEA22279.1 538 tdnfikgrylaeitkevisdlesskyqmaewrisiygrsveewdklaawvvdnklfspnvrWLIQVPRLYDVYKSSGMVNNFEDVIKNLFQPLFEVTQ 635
                  ************************************************************************************************** PP

                  -GC.STCCHHHHCCCCCCCCCCHCCT-EEEEEECCETTTCCGHCCCHHHHHHCCCCCCCCCCCCC-TTSTTGGGHHHHHCCCCHTT-EEEEEESSSS- CS
  A_deaminase 106 gpq.lpelevvlkvvdgfdsvedeskvkerlilvksrkpeewseeinelasyyrdytvvnldllndekiepaslflklraeagkstllltpHaGEagg 202
                  +p+ +p+l+++l++v gfdsv+desk  er++ +k++ p  w  ++n+++sy+ + +++n+++ln            +r+++g++t++l+pH+GEag+
   EEA22279.1 636 DPNtHPKLHIFLQRVIGFDSVDDESK-AERRLYKKYPIPRDWNTKQNPPYSYWIYFMFANMASLN-----------TWRQRRGFNTFVLRPHCGEAGD 721
                  **************************.99************************************...........********************** PP

                  CHHHHHHHHCS--SCECE-GGGGGSHHHHHHHHHCT-EEEE-HHHHCCCSST-TTTT-CHHHHHHTT-EEEE--BSCCCCT-S...HHHHHHHHHHHH CS
  A_deaminase 203 lehvveAllllkaerigHGvrlrkdpvLqyllalaqiplevcPlSNvalgafleyaenPlkeflerglnvslntDDPlqfgtt...LieeYaiaaqvf 297
                  ++h+++ +l   +++i+HG++lrk+p Lqy ++l++i+++++PlSN+al  fl+y++nP+  f+++glnvsl+tDDPlqf +t   L+eeYa+aaq++
   EEA22279.1 722 PDHLAAGFLA--CHSISHGIHLRKVPLLQYVYYLDRIGIAMSPLSNNAL--FLTYDKNPFASFFRKGLNVSLSTDDPLQFAFTkepLMEEYAVAAQIY 815
                  ********99..*************************************..*********************************************** PP

                  T--HHHHHHHHHHHHHCSSS-HHHHHHHCH CS
  A_deaminase 298 klseedlaelarNsvkqsflsadekkklld 327
                  kls++d++ela+Nsv qs+++ + k+++l+
   EEA22279.1 816 KLSAVDMCELAKNSVGQSGFELALKQRWLG 845
                  ****************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1061 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       676  (0.0377043); expected 358.6 (0.02)
Passed bias filter:                      486  (0.0271069); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.84u 0.33s 00:00:01.17 Elapsed: 00:00:00.53
# Mc/sec: 6073.63
//
Query:       EEA22280.1  [L=1474]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    8.2e-05   22.4   0.0     0.0002   21.2   0.0    1.6  1  F-box       F-box domain
     0.0016   18.3   0.0     0.0038   17.1   0.0    1.6  1  F-box-like  F-box-like
  ------ inclusion threshold ------
       0.95    9.2   4.6        1.6    8.5   4.6    1.2  1  DUF445      Protein of unknown function (DUF445)


Domain annotation for each model (and alignments):
>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.0   3.3e-08    0.0002       4      37 ..     119     152 ..     117     159 .. 0.89

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 3.3e-08
                 HHS-HHHHHHHHHTS-HHHHHHHCTT-HHHHHHH CS
       F-box   4 srLPsevlrhILerLplsdllalrrVSkgwrili 37 
                 s LP e+++ I+++L++++l al rV k+++ ++
  EEA22280.1 119 SLLPMEIWHYIFSFLDPKTLGALLRVNKSFHLFL 152
                 67***************************98666 PP

>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   0.0   6.3e-07    0.0038       4      35 ..     121     152 ..     119     156 .. 0.91

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 6.3e-07
  F-box-like   4 LPdEiLlqIFsyLppsdLlrlalVCrrWrrva 35 
                 LP Ei  +IFs+L+p++L +l +V ++++ + 
  EEA22280.1 121 LPMEIWHYIFSFLDPKTLGALLRVNKSFHLFL 152
                 9**************************99765 PP

>> DUF445  Protein of unknown function (DUF445)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   4.6   0.00026       1.6     206     309 ..     498     598 ..     464     611 .. 0.87

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00026
      DUF445 206 lreeedkkvreliadllndpelaakveklkkkklsdlevqeyeealwealkdlllkdlneeesllrerisklleklgeklaed.pklreklnkflenaa 303
                 l ++e ++ +++i++l++++ l+ak e+ +++  ++ + ++ +++ we++++l+++++n      +e+i+k ++k  +  +++  ++++++  +++   
  EEA22280.1 498 LAQREMAE-SKEIERLKESQLLQAKTEERRQQEARSKQDKQALDDQWEDAQRLIRDQINL---YADEIIKKNWNKGTNLTKDQcAQFAAEVLMHVRARF 592
                 55555666.689***********************************************9...689***999999888877779999999999999888 PP

      DUF445 304 akvlek 309
                  + +e+
  EEA22280.1 593 YAHVEE 598
                 777777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1474 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       943  (0.0525964); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.91u 0.31s 00:00:01.22 Elapsed: 00:00:00.49
# Mc/sec: 9035.84
//
Query:       EEA22281.1  [L=287]
Description: acyl-CoA:6-aminopenicillanic-acid-acyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-09   37.9   0.0    5.2e-08   32.9   0.0    2.1  2  AAT       Acyl-coenzyme A:6-aminopenicillanic acid acyl-trans


Domain annotation for each model (and alignments):
>> AAT  Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    3.6   0.0    0.0025        45       4      54 ..      92     151 ..      89     153 .. 0.61
   2 !   32.9   0.0   2.9e-12   5.2e-08      94     225 ..     152     280 ..     148     281 .. 0.88

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.0025
                 SE..EEEEEEE.........E-S-S--EEEEE--S..SS--EEEE..SSSS-SEEEEEETTS CS
         AAT   4 kdgkllgrNeD.........ldpetlsnrflvvasedsgfaslgy..agslpGrtdGiNeaG 54 
                 +++++lg+N+D         ++ ++++n++l++ ++  +++   +  ag + G    +N+aG
  EEA22281.1  92 DNNAFLGQNWDisgqsvpsvWQEKQKQNLILLKITQANKLTIRIMteAGII-GKI-RYNHAG 151
                 5677*******7777666666667777777777666555555444222222.555.555555 PP

  == domain 2  score: 32.9 bits;  conditional E-value: 2.9e-12
                 THHHHTTTS-SEEEEEEETTEEEEEEE-SSS-EEEEEESSEEEEE-SS-S-GGGSSS-----HHHHHHHHHHHHHHCSSSSB...HHHHHHHT---STT CS
         AAT  94 llkeipraaginyivldaagnaavveveasskvcsireanealahtNHfvnetleaenqnilesSisRlerlqellsqkesa...eeaiellkDredep 189
                 +l++   a++ +++v+d++ +a+ ve +++     ir++    +h N f+ + l       l +S+ R+ r++el +  +     +++ + ++D++++p
  EEA22281.1 152 MLEKRGGASSSHMLVADKN-EAFGVESSSTT---MIRDEL--FIHSNLFLLTHLGVVDTKWLGDSPLRVDRMRELSENLSHVpawDTISKVFEDEKNSP 244
                 5778888999999999998.56655444443...466665..8********************************9999998999************** PP

                 TSSSS-...BSSSEEEEEEE-TTS--EEEEEE--TT CS
         AAT 190 ysvlrrksfkswenTiltalydlaarkaklvlgnpk 225
                  s++r   ++s+++T++++++dl+++++ +  g+p+
  EEA22281.1 245 ASICRHEIGSSTVGTLFNIVMDLKQTRVVVRKGKPS 280
                 **************************9998888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (287 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       366  (0.0204139); expected 358.6 (0.02)
Passed bias filter:                      289  (0.0161191); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1933.36
//
Query:       EEA22282.1  [L=775]
Description: actin binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.6e-28   98.3   6.9    4.7e-14   52.0   0.7    2.6  2  SH3_9        Variant SH3 domain
    2.4e-24   84.7  13.0    1.1e-13   50.5   0.6    2.8  3  SH3_1        SH3 domain
    3.7e-17   61.7   0.1    3.5e-09   36.2   0.1    2.6  2  SH3_2        Variant SH3 domain
    1.6e-16   60.2   0.0    3.5e-16   59.1   0.0    1.5  1  Cofilin_ADF  Cofilin/tropomyosin-type actin-binding protein


Domain annotation for each model (and alignments):
>> SH3_9  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.1   0.8   8.3e-17   3.7e-13       2      49 .]     630     678 ..     629     678 .. 0.97
   2 !   52.0   0.7   1.1e-17   4.7e-14       1      49 []     724     772 ..     724     772 .. 0.99

  Alignments for each domain:
  == domain 1  score: 49.1 bits;  conditional E-value: 8.3e-17
       SH3_9   2 lypyepreddeLsLqrGDvitvieesedgWlegsl.tGrtGlvPanyve 49 
                  y+ye  ed e++L +G+++t ie+ +++W++g + +G +Gl+P+nyve
  EEA22282.1 630 QYDYEKAEDNEIELKEGEYVTDIEMVDEDWWLGVNvHGDRGLFPSNYVE 678
                 69***99999**************************************7 PP

  == domain 2  score: 52.0 bits;  conditional E-value: 1.1e-17
       SH3_9   1 AlypyepreddeLsLqrGDvitvieesedgWlegsltGrtGlvPanyve 49 
                 Aly+ye+ ed eLs++ G  i++ie ++d+W+ g+++G+ Gl+Panyve
  EEA22282.1 724 ALYDYEAAEDNELSFPDGAKIVNIEFPDDDWWSGEYDGNVGLFPANYVE 772
                 8***********************************************7 PP

>> SH3_1  SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.5         1   4.5e+03      24      32 ..     211     219 ..     210     219 .. 0.90
   2 !   42.9   0.6   6.1e-15   2.7e-11       1      48 []     628     674 ..     628     674 .. 0.96
   3 !   50.5   0.6   2.5e-17   1.1e-13       1      48 []     723     768 ..     723     768 .. 0.96

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1
                 EEEECSSSE CS
       SH3_1  24 vleksedgW 32 
                 v+++++dgW
  EEA22282.1 211 VVDDDDDGW 219
                 89999**** PP

  == domain 2  score: 42.9 bits;  conditional E-value: 6.1e-15
                 EESSSBEXSSTTBXEBSTTEEEEEEEECSSSEEEEEETTSTEEEEEEG CS
       SH3_1   1 iAlYDYeaeesdELsfkkGDviivleksedgWwkgrlkgtgkeGliPs 48 
                 i+ YDYe+ e++E+ +k+G+ ++ +e+++++Ww g +   g +Gl+Ps
  EEA22282.1 628 IVQYDYEKAEDNEIELKEGEYVTDIEMVDEDWWLGVNVH-GDRGLFPS 674
                 689***********************************9.69*****8 PP

  == domain 3  score: 50.5 bits;  conditional E-value: 2.5e-17
                 EESSSBEXSSTTBXEBSTTEEEEEEEECSSSEEEEEETTSTEEEEEEG CS
       SH3_1   1 iAlYDYeaeesdELsfkkGDviivleksedgWwkgrlkgtgkeGliPs 48 
                 +AlYDYea e++ELsf  G +i ++e  +d+Ww g+++g   +Gl+P+
  EEA22282.1 723 TALYDYEAAEDNELSFPDGAKIVNIEFPDDDWWSGEYDG--NVGLFPA 768
                 59************************************5..6*****6 PP

>> SH3_2  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2   0.1   7.8e-13   3.5e-09       3      56 ..     628     679 ..     626     680 .. 0.90
   2 !   22.9   0.0   1.1e-08     5e-05       5      55 ..     725     772 ..     722     774 .. 0.90

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 7.8e-13
                 EESS-B-SCGCCB--B-TTEEEEEE..EEEECTTEEEEEE.CCCEEEEEGCGEEE CS
       SH3_2   3 raiedyvgedkseLsfkkGdvikvlslgskdsdgwwegev.gGrvGlfPsslvee 56 
                 ++  dy+ +  +e+++k+G+ +  +   +  +++ww+g + +G +GlfPs++ve+
  EEA22282.1 628 IVQYDYEKAEDNEIELKEGEYVTDI---EMVDEDWWLGVNvHGDRGLFPSNYVEI 679
                 67779***************88888...77788********************97 PP

  == domain 2  score: 22.9 bits;  conditional E-value: 1.1e-08
                 SS-B-SCGCCB--B-TTEEEEEE..EEEECTTEEEEEECCCEEEEEGCGEE CS
       SH3_2   5 iedyvgedkseLsfkkGdvikvlslgskdsdgwwegevgGrvGlfPsslve 55 
                 + dy+++  +eLsf  G  i  +   +  +d+ww ge++G vGlfP ++ve
  EEA22282.1 725 LYDYEAAEDNELSFPDGAKIVNI---EFPDDDWWSGEYDGNVGLFPANYVE 772
                 56999999**********99999...66788*******************8 PP

>> Cofilin_ADF  Cofilin/tropomyosin-type actin-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.1   0.0   7.8e-20   3.5e-16      25     121 .]      58     154 ..      50     154 .. 0.86

  Alignments for each domain:
  == domain 1  score: 59.1 bits;  conditional E-value: 7.8e-20
                  TTEEEEEESS-...HHHHHHHHHHTTT-EEEEEEEEEECCSECCEEEEEEEEE--TTS-HHHHHHHHHHHHHHHHHCTTSEEEEEE-CGGCCSHHHHH CS
  Cofilin_ADF  25 keeivveeege...tyeelreelpeseprYavydveyehddeskrsklvfIswvPdsapikqkmlyasskdalkkelkgisveieatdldelteeelk 119
                  ++e v++ +++   ++++l+e+++e+++++a+++v+     ++ ++k v+I+w+++++p ++k  + s+ +a+ + l+g++v+i a++  +lt+e ++
   EEA22282.1  58 NKESVLKVQSSaegELADLIEDFSEGKIQFAFVRVKDP---NTGLPKNVLIAWCGEGVPERTKGYFNSHLAAVGRFLQGYHVQITARSDRDLTPEGIL 152
                  4444444422335888*******************944...466****************************************************99 PP

                  HH CS
  Cofilin_ADF 120 ek 121
                  +k
   EEA22282.1 153 QK 154
                  86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (775 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       477  (0.0266049); expected 358.6 (0.02)
Passed bias filter:                      273  (0.0152267); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.62u 0.26s 00:00:00.88 Elapsed: 00:00:00.44
# Mc/sec: 5328.45
//
Query:       EEA22283.1  [L=774]
Description: dynamin-like GTPase Dnm1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
   2.8e-109  364.8   0.0     6e-109  363.7   0.0    1.6  1  Dynamin_M  Dynamin central region
    1.6e-57  194.2   1.3    6.6e-57  192.2   0.0    2.4  3  Dynamin_N  Dynamin family
    1.4e-31  108.4   1.3    1.4e-31  108.4   1.3    2.2  2  GED        Dynamin GTPase effector domain
    9.6e-05   22.4   0.1    0.00053   20.0   0.1    2.3  1  MMR_HSR1   50S ribosome-binding GTPase


Domain annotation for each model (and alignments):
>> Dynamin_M  Dynamin central region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  363.7   0.0  1.3e-112    6e-109       1     284 [.     226     512 ..     226     513 .. 0.98

  Alignments for each domain:
  == domain 1  score: 363.7 bits;  conditional E-value: 1.3e-112
   Dynamin_M   1 vvdilenkvipLklGYvgVvnRsqkdInkkksieealkkEkaFFeshpayrkladkaGtpyLakkLnqiLvehIrkslPelkkkineklqklekeleel 99 
                 ++dil+++v+pLklG++gVvnRsq+dI+++ks++ealk+E++FF++hpayr++a ++Gt++Lak+Ln++L+ hIr+ lP++k+++n+++ ++++el+++
  EEA22283.1 226 ALDILSGRVYPLKLGFIGVVNRSQQDIQSGKSLSEALKAEADFFRHHPAYRNMAIRCGTQFLAKTLNSTLMAHIRDRLPDIKARLNTLMGQTQQELASY 324
                 68************************************************************************************************* PP

   Dynamin_M 100 geskpsde.ektklllqlitkfkedfkklieGe.sevstkelsggarireiFnetlekslekidpleelsdeeirtairnsrGrelplfvpekaFealv 196
                 g+++ s + ++++l+lql+t f+++f ++i+G+ se+stkel+ggari++iFn+++++sle+idp+++l+  +irtairns+G++++lfvpe aF+ lv
  EEA22283.1 325 GNKQFSGKeHRGSLILQLMTRFASSFISSIDGTsSEISTKELCGGARIYYIFNSVFGHSLETIDPTHNLTVYDIRTAIRNSTGPRPSLFVPELAFDLLV 423
                 *88777778************************55599************************************************************* PP

   Dynamin_M 197 kkqikkleepalkcvelVyeelekiveklek.elkrFpnLreeikevvedllreqeeptkemienliemelayintnhpdfigalkair 284
                 k+qik le p+++cvelVyeel+ki++++ + el+rFp+L+ ++ evv+dllre++ p+  ++e+li++++ayintnhp+f+ga++a++
  EEA22283.1 424 KPQIKLLEIPSQRCVELVYEELIKICHTCGSqELSRFPRLQGKLIEVVSDLLRERLGPCSTYVESLIAIQRAYINTNHPNFLGAAAAMS 512
                 ****************************9999*****************************************************9986 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  192.2   0.0   1.5e-60   6.6e-57       1     167 [.      33     216 ..      33     217 .. 0.95
   2 ?   -0.2   0.3      0.21   9.4e+02      37      81 ..     514     558 ..     488     583 .. 0.57
   3 ?   -3.9   0.0       2.7   1.2e+04       3      27 ..     590     614 ..     590     616 .. 0.77

  Alignments for each domain:
  == domain 1  score: 192.2 bits;  conditional E-value: 1.5e-60
                 EEEEEBTTTTHHHHHHHHHTS--S---SSS---S-EEEEE...CCT---CCS...SSEEEE....T-EB--CHHHHHHHHHHHHHHHTSSSS--SS-EE CS
   Dynamin_N   1 iavvGsqSsGKSSvlnaLlgedilprgpnptTrrplelql...geeeeaseravkeelkek....ekkledfsevreeieketekiagankgiskkvil 92 
                 i+vvGsqSsGKSSvl++++g+d+lprg++++Trrpl+lql   ++ee+ s+ a+  e+ e+     +k+edf +v++eie+et++iag+nkgi++++i+
  EEA22283.1  33 IVVVGSQSSGKSSVLENIVGRDFLPRGSGIVTRRPLILQLinvSDEEDDSSLAAPGEWAEFhhlpGRKFEDFAQVKQEIENETARIAGSNKGINRQPIN 131
                 89**************************************6663333334678889999999999********************************** PP

                 EEEEETTS-SEEEEE---B-SSSGTTS.........HHHHHHH.STTEEEEEEEETTS-CCC-CHHHHHHHHSTTBTTEEEEEE- CS
   Dynamin_N  93 lkilsllvkgltlvDlPGldsvnkrdq.........elvkeyi.kkadiilavtsanhdlsnsealflarevdpkgkrtivvltk 167
                 lki+s++v +ltlvDlPGl++v+ +dq          l+ eyi k+++iilav++an+dl nseal+lar+vdp g+rti+vltk
  EEA22283.1 132 LKIFSPHVLNLTLVDLPGLTKVPIGDQpsdiekqtrTLISEYIaKPNSIILAVSPANVDLVNSEALKLARHVDPMGRRTIGVLTK 216
                 ************************************************************************************9 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.21
                 EEEECCT---CCS...SSEEEET-EB--CHHHHHHHHHHHHHHHT CS
   Dynamin_N  37 elqlgeeeeaseravkeelkekekkledfsevreeieketekiag 81 
                 ++q ++e+e + + ++e+ k ++++l+++ e +   e+ ++++a+
  EEA22283.1 514 VVQNKQEQEKKAMLAEERKKREKRRLKEMGETNGVTEEDEDQHAE 558
                 455555555443333333333344444444444444444444433 PP

  == domain 3  score: -3.9 bits;  conditional E-value: 2.7
                 EEEBTTTTHHHHHHHHHTS--S--- CS
   Dynamin_N   3 vvGsqSsGKSSvlnaLlgedilprg 27 
                 v+G+ +    S+ln   g+d  p++
  EEA22283.1 590 VFGAANTARDSFLNYFFGKDGVPSS 614
                 56666666679*******9988875 PP

>> GED  Dynamin GTPase effector domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.7      0.73   3.3e+03      41      72 ..     519     537 ..     508     546 .. 0.53
   2 !  108.4   1.3   3.2e-35   1.4e-31       2      92 .]     683     773 ..     682     773 .. 0.98

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.73
                 HCCCCCHHHCCTTSGGGHHHHT---SCHCCCC CS
         GED  41 keslqkellakLykkedldeLLkEdeeiaekR 72 
                 +e+               + +L+E+ +  ekR
  EEA22283.1 519 QEQE-------------KKAMLAEERKKREKR 537
                 2222.............455555555555555 PP

  == domain 2  score: 108.4 bits;  conditional E-value: 3.2e-35
                 XXXXTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHCCCCCHHHCCTTSGGGHHHHT---SCHCCCCHHHHHHHHHHHHHCCCCCHH CS
         GED   2 eeseveeirslvksYfnivrktiadqiPkaimhllvneakeslqkellakLykkedldeLLkEdeeiaekRkelkkrlealkkAreilsev 92 
                 e +e+e ir+l++sYfnivr+tiadq+Pka+mhllvn++k+ +q++l+++Lyk+e +++LL Ed+ i+++R+++++ le++k+A +i+ ev
  EEA22283.1 683 EIMETELIRRLISSYFNIVRETIADQVPKAVMHLLVNHSKDVVQNRLVSELYKEELFSDLLYEDDGIKAEREKCERLLETYKEAAKIVGEV 773
                 6799***********************************************************************************9986 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   0.1   1.2e-07   0.00053       1      96 [.      32     195 ..      32     216 .. 0.71

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 1.2e-07
                 EEEEEESTTSSHHHHHHHHHTSTEEESSSTTSSSSEEEEEEE.ETTEE................................................... CS
    MMR_HSR1   1 evaivGrpNvGKStLinaltgekaivsdkpgtTrdinegrvk.lkgke................................................... 47 
                 ++++vG   +GKS+++  ++g+         +Tr +   ++  ++++e                                                   
  EEA22283.1  32 QIVVVGSQSSGKSSVLENIVGRDFLPRGSGIVTRRPLILQLInVSDEEddsslaapgewaefhhlpgrkfedfaqvkqeienetariagsnkginrqpi 130
                 589*******************99999999999999655543244433577899999999999999********************************* PP

                 ...........EEEEECGGC...........SSHHHHHHHHHHHHHHHHCTSEEEEEEETTTTCSHHHHHH CS
    MMR_HSR1  48 ...........ielvDtpGl...........iegaseekglgkaflaleeadlillvvdaseeklkpldee 96 
                            ++lvD+pGl           i  +++ + l  ++ a+ + ++il v  a+   ++ +++e
  EEA22283.1 131 nlkifsphvlnLTLVDLPGLtkvpigdqpsdI--EKQTRTLISEYIAKPN-SIILAVSPAN---VDLVNSE 195
                 *******************8444322221111..2223345555554322.4455444433...3333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (774 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1216  (0.0678231); expected 358.6 (0.02)
Passed bias filter:                      826  (0.0460706); expected 358.6 (0.02)
Passed Vit filter:                        96  (0.00535445); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.85u 0.34s 00:00:01.19 Elapsed: 00:00:00.50
# Mc/sec: 4651.09
//
Query:       EEA22284.1  [L=559]
Description: UPD-GlcNAc transporter (Mnn2-2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      4e-84  282.4  12.1    8.7e-59  199.2   0.7    2.1  2  UAA             UAA transporter family
    4.6e-05   22.7   0.2    4.6e-05   22.7   0.2    1.8  2  Nuc_sug_transp  Nucleotide-sugar transporter
  ------ inclusion threshold ------
      0.028   13.9   7.9      0.088   12.3   0.7    2.4  2  SLC35F          Solute carrier family 35


Domain annotation for each model (and alignments):
>> UAA  UAA transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  199.2   0.7   1.5e-62   8.7e-59       4     228 ..      91     338 ..      88     376 .. 0.90
   2 !   87.8   5.0   1.2e-28   7.4e-25     205     298 ..     397     492 ..     378     496 .. 0.88

  Alignments for each domain:
  == domain 1  score: 199.2 bits;  conditional E-value: 1.5e-62
         UAA   4 lavslvfvgccsnvvllElivkeepkafgnlltfvqflfvalegllesid........ilkkrkiPlktYvilvalffitsvlnnealkydisvPvhii 94 
                 ++ +l+f+gcc nv++lE i+k+ep a g l+tfvqf++v+l+ +++ ++        + k ++iPl+ + i  ++f++++ lnn a++y+isvP+hii
  EEA22284.1  91 IVGTLIFGGCCGNVFALEAIIKDEPAA-GPLITFVQFVTVSLFTIPSFLSwsagassfFMKAPVIPLRSWTIYTLFFVTVNLLNNWAFAYHISVPLHII 188
                 56689**********************.*******************999887776655**************************************** PP

         UAA  95 frssklipvmilGililgkrYsllqylsvllltlGviiftllsakdk........kedskeslnkfllGiallvlallldavlglvqeklykkygk.hs 184
                 +rs++  + mi+G   +g+rYs +q+ sv+lltlGv+ ++l++ak +          d  + + +f++G+++l+la+ll+a+ g++ ++ly  +g+ h+
  EEA22284.1 189 LRSGGPTASMIIGYWYNGRRYSRMQIFSVMLLTLGVVAAALADAKAQgkaislssGGDGDKPTLTFVTGFTILALAMLLSAFQGVYADRLYATHGNtHW 287
                 *****************************************99999999****997788888999****************************985389 PP

         UAA 185 kealfyshllslplflllqgellsavkflsesedval.......lslpskl 228
                 +eal+ysh+lslp+fl  + +l s+++++ +s+++          s+p+ l
  EEA22284.1 288 REALLYSHMLSLPFFLPTYAQLSSQFRAFMSSPSMLAdlhpaaaGSVPQDL 338
                 9********************************999766666665555554 PP

  == domain 2  score: 87.8 bits;  conditional E-value: 1.2e-28
         UAA 205 ellsavkflsesedval..lslpsklfylllnvltqyvcikgVlilisefgaltvtlvltlRKfvslllSillFknpltlqhlvgtllVflgllly 298
                 ++lsa +++ +   ++    + psk+fyl++n+ltqy+ci+gV++l++++++ltvt+vl++RK+vslllSi++F+n l++  l+g+ +Vflg +ly
  EEA22284.1 397 NILSASTDAMQRDLLTTilNKTPSKIFYLIVNALTQYICIRGVYLLAAKSSSLTVTIVLNIRKLVSLLLSIYIFGNSLAAGVLIGAGFVFLGGALY 492
                 4555555555555555566789***********************************************************************998 PP

>> Nuc_sug_transp  Nucleotide-sugar transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   0.2   7.7e-09   4.6e-05     100     208 ..     165     287 ..     153     310 .. 0.73
   2 ?   -2.8   1.6      0.45   2.7e+03     282     314 ..     460     492 ..     421     493 .. 0.78

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 7.7e-09
  Nuc_sug_transp 100 lyvalsnLd..aatyqvtyqlkil.....tta..lfsvllLkrklskkqWlslllLvaGvalvqlkqkeseesekaaaaa.....keensvlGli 180
                      +v+++ L+  a +y ++  l i+      ta  ++ +   +r+ s++q +s++lL++Gv+   l++++++ +  + ++       +   v+G++
      EEA22284.1 165 FFVTVNLLNnwAFAYHISVPLHIIlrsggPTAsmIIGYWYNGRRYSRMQIFSVMLLTLGVVAAALADAKAQGKAISLSSGgdgdkPTLTFVTGFT 259
                     555555554336667777777776333332441134456678*******************9999998887776655555565556667799*** PP

  Nuc_sug_transp 181 avlaacllsgfaGvYfekiLkdsnvslW 208
                      +  a+lls+f GvY +++  +  ++ W
      EEA22284.1 260 ILALAMLLSAFQGVYADRLYATHGNTHW 287
                     ****************999887777777 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.45
  Nuc_sug_transp 282 ilstvasvllldlkitllFllGallviaavflY 314
                     ++s + s+++++ +++   l+Ga  v +   lY
      EEA22284.1 460 LVSLLLSIYIFGNSLAAGVLIGAGFVFLGGALY 492
                     356788999999999999999999988777666 PP

>> SLC35F  Solute carrier family 35
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.7   1.5e-05     0.088      19     169 ..     100     253 ..      85     271 .. 0.69
   2 ?    5.1   1.3    0.0022        13     212     293 ..     406     488 ..     381     500 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.5e-05
      SLC35F  19 itataltskylaekkinaPvlqtflnyvllalvyt.gillfrrgaeklle...ilkrkwykylllalvdveanylvvkayqytsltsv.qlldcfaipv 112
                 ++++ +  + + +++  a  l tf+++v + l    ++l +  ga  +++   ++  + +   +++l+ v  n l   a+ y   + +  +l + + ++
  EEA22284.1 100 CCGNVFALEAIIKDEPAAGPLITFVQFVTVSLFTIpSFLSWSAGASSFFMkapVIPLRSW--TIYTLFFVTVNLLNNWAFAYHISVPLhIILRSGGPTA 196
                 555555555566665555556688888777765441455666677666642334555555..4566667777888888888865444415678888889 PP

      SLC35F 113 vlvlswlflkvryrlvkiigvvvcilGvvllvvsdvlagrransgsnpvlGdllvla 169
                  +++ + +   ry  ++i +v++  lGvv    +d  a  +a s s    Gd   l+
  EEA22284.1 197 SMIIGYWYNGRRYSRMQIFSVMLLTLGVVAAALADAKAQGKAISLSSGGDGDKPTLT 253
                 99************************************9999888888888854443 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0022
      SLC35F 212 lerkelkaihW.daeiallfvgfalvlfllysllpilikktsatsvnlslltsdlyslliglflfhykvswlyllafvviliG 293
                 ++r+ l++i   +   +++++  al+ ++    + +l  k+s+ +v++ l    l sll+ +++f++ +    l+    + +G
  EEA22284.1 406 MQRDLLTTILNkTPSKIFYLIVNALTQYICIRGVYLLAAKSSSLTVTIVLNIRKLVSLLLSIYIFGNSLAAGVLIGAGFVFLG 488
                 55555555543034556677777888888777788888888888889999999999999999999887766555554444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (559 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       852  (0.0475208); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.63u 0.31s 00:00:00.94 Elapsed: 00:00:00.50
# Mc/sec: 3335.07
//
Query:       EEA22285.1  [L=560]
Description: UPD-GlcNAc transporter (Mnn2-2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.1e-84  282.3  12.1    8.7e-59  199.2   0.7    2.1  2  UAA             UAA transporter family
    4.6e-05   22.7   0.2    4.6e-05   22.7   0.2    1.8  2  Nuc_sug_transp  Nucleotide-sugar transporter
  ------ inclusion threshold ------
      0.028   13.9   7.9      0.088   12.3   0.7    2.4  2  SLC35F          Solute carrier family 35


Domain annotation for each model (and alignments):
>> UAA  UAA transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  199.2   0.7   1.5e-62   8.7e-59       4     228 ..      92     339 ..      89     377 .. 0.90
   2 !   87.8   5.0   1.2e-28   7.4e-25     205     298 ..     398     493 ..     379     497 .. 0.88

  Alignments for each domain:
  == domain 1  score: 199.2 bits;  conditional E-value: 1.5e-62
         UAA   4 lavslvfvgccsnvvllElivkeepkafgnlltfvqflfvalegllesid........ilkkrkiPlktYvilvalffitsvlnnealkydisvPvhii 94 
                 ++ +l+f+gcc nv++lE i+k+ep a g l+tfvqf++v+l+ +++ ++        + k ++iPl+ + i  ++f++++ lnn a++y+isvP+hii
  EEA22285.1  92 IVGTLIFGGCCGNVFALEAIIKDEPAA-GPLITFVQFVTVSLFTIPSFLSwsagassfFMKAPVIPLRSWTIYTLFFVTVNLLNNWAFAYHISVPLHII 189
                 56689**********************.*******************999887776655**************************************** PP

         UAA  95 frssklipvmilGililgkrYsllqylsvllltlGviiftllsakdk........kedskeslnkfllGiallvlallldavlglvqeklykkygk.hs 184
                 +rs++  + mi+G   +g+rYs +q+ sv+lltlGv+ ++l++ak +          d  + + +f++G+++l+la+ll+a+ g++ ++ly  +g+ h+
  EEA22285.1 190 LRSGGPTASMIIGYWYNGRRYSRMQIFSVMLLTLGVVAAALADAKAQgkaislssGGDGDKPTLTFVTGFTILALAMLLSAFQGVYADRLYATHGNtHW 288
                 *****************************************99999999****997788888999****************************985389 PP

         UAA 185 kealfyshllslplflllqgellsavkflsesedval.......lslpskl 228
                 +eal+ysh+lslp+fl  + +l s+++++ +s+++          s+p+ l
  EEA22285.1 289 REALLYSHMLSLPFFLPTYAQLSSQFRAFMSSPSMLAdlhpaaaGSVPQDL 339
                 9********************************999766666665555554 PP

  == domain 2  score: 87.8 bits;  conditional E-value: 1.2e-28
         UAA 205 ellsavkflsesedval..lslpsklfylllnvltqyvcikgVlilisefgaltvtlvltlRKfvslllSillFknpltlqhlvgtllVflgllly 298
                 ++lsa +++ +   ++    + psk+fyl++n+ltqy+ci+gV++l++++++ltvt+vl++RK+vslllSi++F+n l++  l+g+ +Vflg +ly
  EEA22285.1 398 NILSASTDAMQRDLLTTilNKTPSKIFYLIVNALTQYICIRGVYLLAAKSSSLTVTIVLNIRKLVSLLLSIYIFGNSLAAGVLIGAGFVFLGGALY 493
                 4555555555555555566789***********************************************************************998 PP

>> Nuc_sug_transp  Nucleotide-sugar transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   0.2   7.7e-09   4.6e-05     100     208 ..     166     288 ..     154     311 .. 0.73
   2 ?   -2.8   1.6      0.45   2.7e+03     282     314 ..     461     493 ..     422     494 .. 0.78

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 7.7e-09
  Nuc_sug_transp 100 lyvalsnLd..aatyqvtyqlkil.....tta..lfsvllLkrklskkqWlslllLvaGvalvqlkqkeseesekaaaaa.....keensvlGli 180
                      +v+++ L+  a +y ++  l i+      ta  ++ +   +r+ s++q +s++lL++Gv+   l++++++ +  + ++       +   v+G++
      EEA22285.1 166 FFVTVNLLNnwAFAYHISVPLHIIlrsggPTAsmIIGYWYNGRRYSRMQIFSVMLLTLGVVAAALADAKAQGKAISLSSGgdgdkPTLTFVTGFT 260
                     555555554336667777777776333332441134456678*******************9999998887776655555565556667799*** PP

  Nuc_sug_transp 181 avlaacllsgfaGvYfekiLkdsnvslW 208
                      +  a+lls+f GvY +++  +  ++ W
      EEA22285.1 261 ILALAMLLSAFQGVYADRLYATHGNTHW 288
                     ****************999887777777 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.45
  Nuc_sug_transp 282 ilstvasvllldlkitllFllGallviaavflY 314
                     ++s + s+++++ +++   l+Ga  v +   lY
      EEA22285.1 461 LVSLLLSIYIFGNSLAAGVLIGAGFVFLGGALY 493
                     356788999999999999999999988777666 PP

>> SLC35F  Solute carrier family 35
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.7   1.5e-05     0.088      19     169 ..     101     254 ..      86     272 .. 0.69
   2 ?    5.1   1.3    0.0022        13     212     293 ..     407     489 ..     382     501 .. 0.69

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.5e-05
      SLC35F  19 itataltskylaekkinaPvlqtflnyvllalvyt.gillfrrgaeklle...ilkrkwykylllalvdveanylvvkayqytsltsv.qlldcfaipv 112
                 ++++ +  + + +++  a  l tf+++v + l    ++l +  ga  +++   ++  + +   +++l+ v  n l   a+ y   + +  +l + + ++
  EEA22285.1 101 CCGNVFALEAIIKDEPAAGPLITFVQFVTVSLFTIpSFLSWSAGASSFFMkapVIPLRSW--TIYTLFFVTVNLLNNWAFAYHISVPLhIILRSGGPTA 197
                 555555555566665555556688888777765441455666677666642334555555..4566667777888888888865444415678888889 PP

      SLC35F 113 vlvlswlflkvryrlvkiigvvvcilGvvllvvsdvlagrransgsnpvlGdllvla 169
                  +++ + +   ry  ++i +v++  lGvv    +d  a  +a s s    Gd   l+
  EEA22285.1 198 SMIIGYWYNGRRYSRMQIFSVMLLTLGVVAAALADAKAQGKAISLSSGGDGDKPTLT 254
                 99************************************9999888888888854443 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.0022
      SLC35F 212 lerkelkaihW.daeiallfvgfalvlfllysllpilikktsatsvnlslltsdlyslliglflfhykvswlyllafvviliG 293
                 ++r+ l++i   +   +++++  al+ ++    + +l  k+s+ +v++ l    l sll+ +++f++ +    l+    + +G
  EEA22285.1 407 MQRDLLTTILNkTPSKIFYLIVNALTQYICIRGVYLLAAKSSSLTVTIVLNIRKLVSLLLSIYIFGNSLAAGVLIGAGFVFLG 489
                 55555555543034556677777888888777788888888888889999999999999999999887766555554444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (560 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       876  (0.0488594); expected 358.6 (0.02)
Passed bias filter:                      427  (0.0238162); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.64u 0.29s 00:00:00.93 Elapsed: 00:00:00.45
# Mc/sec: 3718.31
//
Query:       EEA22286.1  [L=883]
Description: cell cycle checkpoint protein Rad17, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.3e-30  104.1   0.0      2e-29  102.8   0.0    1.6  1  Rad17         Rad17 P-loop domain
    3.8e-05   24.2   0.0    8.4e-05   23.0   0.0    1.6  1  AAA_16        AAA ATPase domain
    0.00016   22.0   0.0    0.00036   20.8   0.0    1.6  1  AAA_22        AAA domain
    0.00017   22.0   0.0    0.00044   20.7   0.0    1.8  1  AAA           ATPase family associated with various cellular 
     0.0099   15.8   0.0      0.021   14.7   0.0    1.5  1  RsgA_GTPase   RsgA GTPase
  ------ inclusion threshold ------
      0.021   15.3   0.3      0.099   13.2   0.0    2.3  2  ABC_tran      ABC transporter
      0.023   13.8   0.0      0.048   12.7   0.0    1.5  1  T2SSE         Type II/IV secretion system protein
      0.034   13.3   0.0      0.055   12.6   0.0    1.3  1  NB-ARC        NB-ARC domain
      0.043   14.2   0.0      0.097   13.1   0.0    1.6  1  RNA_helicase  RNA helicase
       0.05   13.3   0.0       0.15   11.8   0.0    1.7  2  AAA_30        AAA domain
       0.05   13.6   0.0        0.1   12.6   0.0    1.4  1  TsaE          Threonylcarbamoyl adenosine biosynthesis protei
      0.058   13.1   0.0       0.11   12.2   0.0    1.4  1  RuvB_N        Holliday junction DNA helicase RuvB P-loop doma
       0.15   12.1   0.0       0.41   10.7   0.0    1.7  1  AAA_14        AAA domain
       0.22   11.7   3.8       0.49   10.5   3.8    1.6  1  DUF2057       Uncharacterized protein conserved in bacteria (
        0.3   10.8   4.1       0.31   10.8   0.0    2.2  2  AAA_11        AAA domain


Domain annotation for each model (and alignments):
>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.8   0.0   1.7e-32     2e-29       4     165 ..     219     391 ..     216     423 .. 0.80

  Alignments for each domain:
  == domain 1  score: 102.8 bits;  conditional E-value: 1.7e-32
       Rad17   4 denelWfekykPekaeelavhkkkieevkewlkadvLesrkkriLLisGPsGCgkstvvkvLskelgiklrewlnpvslkepdnqksdfkgltekesrf 102
                  +  +W eky P+  ++lavhkkk+ +v+ewl a    + +++iL++ GP+GCgk+t+v  Ls el +++++w  p s   +d  + ++ +l  + + f
  EEA22286.1 219 TDRRPWSEKYAPHVIDHLAVHKKKVADVREWLSAALSGRSRHKILVLHGPAGCGKTTTVSLLSDELKFDIIDWKSPFS---TDSGNGQYTSLSAQLDDF 314
                 56789************************************************************************9...788888888888899999 PP

       Rad17 103 lsqiesfkeleLk...........dakylklqklGddlrtdkklilvedlP.nkfyrds..dalrevirkylrssea 165
                 lsq++ f+ l L            +a    ++k+     + k++il+e++P n   +++    ++  +r+yl ss +
  EEA22286.1 315 LSQLNGFSGLDLSyssasssssssSASKSSISKQTPGQTARKRVILIEEFPaNLSWGSTtlSLFQTSLRRYLASSSP 391
                 99999999999862222221111122344677777788889**********5444455445789********99876 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.0   0.0   7.1e-08   8.4e-05       9      52 ..     243     301 ..     238     411 .. 0.70

  Alignments for each domain:
  == domain 1  score: 23.0 bits;  conditional E-value: 7.1e-08
      AAA_16   9 leqLlsalervrsgrp..elvllsGesGvGKsslvrellralekd.............g 52 
                 ++ +++ l+++ sgr+   +++l+G++G+GK++ v  l ++l+ d             +
  EEA22286.1 243 VADVREWLSAALSGRSrhKILVLHGPAGCGKTTTVSLLSDELKFDiidwkspfstdsgN 301
                 667788899999999999*******************9998887755554444444431 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8   0.0   3.1e-07   0.00036       4     102 ..     259     366 ..     256     399 .. 0.64

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 3.1e-07
      AAA_22   4 tagilvvtGesGtGKTtllrrlleqldeeakaee....erpevv...fvtlpsst.sskdllrellralglelka.....erlsseellealeqalrar 89 
                 +++ilv++G++G+GKTt++  l ++l+   ++ +               + +s++  ++d+l++l  + gl+l++     +  ss++  + + ++    
  EEA22286.1 259 RHKILVLHGPAGCGKTTTVSLLSDELK--FDIIDwkspF---STdsgNGQYTSLSaQLDDFLSQLNGFSGLDLSYssassSSSSSSASKSSISKQ---- 348
                 789**********************93..2222243331...22344344444445788888888888888888855444222222333333333.... PP

      AAA_22  90 av......ielliiDEaqh 102
                  +      +++++i+E+  
  EEA22286.1 349 -TpgqtarKRVILIEEFPA 366
                 .224444778888888755 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.7   0.0   3.7e-07   0.00044       2      38 ..     264     314 ..     263     415 .. 0.72

  Alignments for each domain:
  == domain 1  score: 20.7 bits;  conditional E-value: 3.7e-07
                 EEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSS..............S CS
         AAA   2 llyGppGtGKTllakavakelgvefleisgsellsk..............y 38 
                 +l+Gp G+GKT++++ +  el+++++  + +  +++              +
  EEA22286.1 264 VLHGPAGCGKTTTVSLLSDELKFDIIDWKSPFSTDSgngqytslsaqlddF 314
                 79********************99998888776655455544444444440 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   1.7e-05     0.021      64     146 ..     220     311 ..     208     320 .. 0.68

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 1.7e-05
                  HHHHHHHHHHHTTSEEEE--TTTHTTHH.....HHHHHCTTSEEEEECSTTSSHHHHHHHHCTT-----....S--------------SEEE CS
  RsgA_GTPase  64 eleelkeelealgyevllvsaktkegle.....elkellkdktsvlvGqSGvGKStLinallpelelkt....gevseklgrGkhTTtavel 146
                  + + ++e+++   ++ l+v++k+ ++++     +l+ + ++k+ vl G+ G GK+t +  l  el+  +    +  s+++g+G+ T+ +++l
   EEA22286.1 220 DRRPWSEKYAPHVIDHLAVHKKKVADVRewlsaALSGRSRHKILVLHGPAGCGKTTTVSLLSDELKFDIidwkSPFSTDSGNGQYTSLSAQL 311
                  4566666676666666666666554443111113444556799********************98877622225578899999999988877 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   8.3e-05     0.099      10      36 ..     259     285 ..     250     374 .. 0.87
   2 ?   -2.0   0.0       3.9   4.7e+03      80     120 ..     533     574 ..     459     575 .. 0.59

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 8.3e-05
                 TTSEEEEEESTTSSHHHHHHHHTTSS- CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  10 egekvaivGenGaGKStLlkllagllk 36 
                 + +++++ G+ G+GK+t ++ll+ +lk
  EEA22286.1 259 RHKILVLHGPAGCGKTTTVSLLSDELK 285
                 568999****************99876 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 3.9
                 HHHTCHHHHHHHSTTGGTTCBGESTTS.GGS-HHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxx RF
    ABC_tran  80 esdeeiekalsklglkelkdtvvkssp.ssLSgGqkqrvala 120
                 es e i++  ++lgl +   +vv+++  +++  Gq+q + +a
  EEA22286.1 533 ESLELITQRETSLGLFHAVGKVVYNKRdENVDPGQQQEIHVA 574
                 333336666677777777777776666688888888887765 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0     4e-05     0.048     105     154 ..     233     285 ..     214     290 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 4e-05
       T2SSE 105 lddlgaeealkekiaevlrkavr...erglilvsGgTgsGKttllyallkein 154
                 +d+l+++++  ++++e l++a++   +++++++ G+ g GKtt++  l  e++
  EEA22286.1 233 IDHLAVHKKKVADVREWLSAALSgrsRHKILVLHGPAGCGKTTTVSLLSDELK 285
                 678888888888899999888853337888999***********999888775 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   4.6e-05     0.055       3      39 ..     241     279 ..     239     323 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 4.6e-05
                 HHHHHHHHHHHC..TTTSCSEEEEEEESTTSSHHHHHHH CS
      NB-ARC   3 ksvekviekLle..kdelqslvvalvGmgGvGKttlakq 39 
                 k+v  v e+L+   ++ +   ++ l+G +G+GKtt ++ 
  EEA22286.1 241 KKVADVREWLSAalSGRSRHKILVLHGPAGCGKTTTVSL 279
                 567777788876556666778**************7764 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   8.1e-05     0.097       1      35 [.     263     296 ..     263     320 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 8.1e-05
  RNA_helicase   1 iwlyGpsgeGKStlakeLakallkklklkkkdsvy 35 
                   ++l+Gp+g+GK+t++  L+++l  ++  ++k+ + 
    EEA22286.1 263 LVLHGPAGCGKTTTVSLLSDELKFDI-IDWKSPFS 296
                   589*****************999777.44444443 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       4.9   5.8e+03      46      81 ..      85     120 ..      76     130 .. 0.74
   2 ?   11.8   0.0   0.00012      0.15      16      38 ..     258     280 ..     249     285 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 4.9
      AAA_30  46 ggrviglAptgkaAkvLaeelgieastiakllkrlk 81 
                 + +v   +p++ka ++ +++ g ++++++++ +  +
  EEA22286.1  85 KVEVSSPSPQKKARQQKQQQQGEPTRSLHNFFQPAT 120
                 566677788889999999999999999999987666 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 0.00012
      AAA_30  16 sgdrvavltGpAGtGKttalkal 38 
                 s++++ vl+GpAG GKtt+++ l
  EEA22286.1 258 SRHKILVLHGPAGCGKTTTVSLL 280
                 678899*************9876 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   8.4e-05       0.1      12      51 ..     248     294 ..     238     297 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 8.4e-05
                 HHHHHCH.....TEEEEEEESTTSSHHHHHHHHHHHTT--..----T CS
        TsaE  12 kklakal.....gdvilLeGdLGaGKTtlvrglakalgve..evkSP 51 
                 + l +al     +++++L+G+ G+GKTt v  l  +l+++  + kSP
  EEA22286.1 248 EWLSAALsgrsrHKILVLHGPAGCGKTTTVSLLSDELKFDiiDWKSP 294
                 445444455445778**********************9988888888 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   9.2e-05      0.11      11      67 ..     238     294 ..     229     313 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 9.2e-05
      RuvB_N  11 gqekvkeklkifieaakkreealdhvllyGpPGlGkttlakiiakelgvklkitsgP 67 
                   +k  ++++  ++aa + ++    ++l+Gp G Gktt  +++++el+ ++    +P
  EEA22286.1 238 VHKKKVADVREWLSAALSGRSRHKILVLHGPAGCGKTTTVSLLSDELKFDIIDWKSP 294
                 555555566667788888777888899********************9988655555 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00034      0.41       2      27 ..     260     285 ..     259     320 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00034
      AAA_14   2 rkilvitGaRrvGKTtllkqlikell 27 
                 +kilv+ G+  +GKTt +  l +el 
  EEA22286.1 260 HKILVLHGPAGCGKTTTVSLLSDELK 285
                 79***************988876665 PP

>> DUF2057  Uncharacterized protein conserved in bacteria (DUF2057)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   3.8   0.00041      0.49      83     191 ..      16     128 ..      11     129 .. 0.62

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00041
     DUF2057  83 enerqakafakspkitltdksgks....veakqdklk.kegfqlgrdyeqelaeynrsgaaaaaataatataataavaaaaskssataqgqnqaeqmLq 176
                 +++++ + f+ sp++++   ++k     v +++   k  +   +    ++e +e +++ a+   ++  +++++ ++++++++  ++++q+q + +++L+
  EEA22286.1  16 SSSDNEESFITSPSVEINSPEKKNkpmlVVSRENPSKrVKTTTTSMRAKPEPSEKGNTRAPSRRSKKDSKVEVSSPSPQKKA-RQQKQQQQGEPTRSLH 113
                 5677788899999999998866666785333333333445555555556666666666666644444444444444444433.44445555555668** PP

     DUF2057 177 ywylqAdketrkeFl 191
                   ++ A++e+r  F 
  EEA22286.1 114 NFFQPATDEQRWSFS 128
                 ***********8885 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   3.8       2.3   2.7e+03      89     146 ..      40     103 ..       6     154 .. 0.47
   2 ?   10.8   0.0   0.00026      0.31      10      41 ..     250     284 ..     243     353 .. 0.76

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 2.3
      AAA_11  89 kivRvgneeeriseavksvsleekvekrlekee.........kaqlakeiskeleklakelrafeee 146
                 k + v++ e ++s++vk  +  +++++++e +e         + ++ ++++ ++ + +k++r+++++
  EEA22286.1  40 KPMLVVSRE-NPSKRVKTTT--TSMRAKPEPSEkgntrapsrRSKKDSKVEVSSPSPQKKARQQKQQ 103
                 333344444.3344444444..333333333321222222221111111111111111111111111 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00026
      AAA_11  10 iksalsese...itliqGPPGtgKTktivellsql 41 
                 ++ als ++   i +++GP G+gKT+t+  l  +l
  EEA22286.1 250 LSAALSGRSrhkILVLHGPAGCGKTTTVSLLSDEL 284
                 55555555455599*************98877776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (883 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       940  (0.052429); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        84  (0.00468515); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.77u 0.28s 00:00:01.05 Elapsed: 00:00:00.43
# Mc/sec: 6222.55
//
Query:       EEA22287.1  [L=752]
Description: ELMO/CED-12 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.8e-53  181.3   0.1    3.1e-53  180.5   0.1    1.4  1  ELMO_CED12  ELMO/CED-12 family
    1.4e-35  122.7   0.2    8.4e-34  117.0   0.2    2.6  1  PH_12       Pleckstrin homology domain
    1.4e-15   57.6   0.0    3.2e-15   56.4   0.0    1.6  1  DUF3361     Domain of unknown function (DUF3361)
  ------ inclusion threshold ------
      0.071   12.5   0.5       0.13   11.7   0.5    1.3  1  DUF3552     Domain of unknown function (DUF3552)
        0.1   13.3   0.2        0.1   13.3   0.2    2.0  2  PCNP        PEST, proteolytic signal-containing nuclear prote


Domain annotation for each model (and alignments):
>> ELMO_CED12  ELMO/CED-12 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  180.5   0.1   8.6e-57   3.1e-53       2     176 ..     231     426 ..     230     427 .. 0.97

  Alignments for each domain:
  == domain 1  score: 180.5 bits;  conditional E-value: 8.6e-57
  ELMO_CED12   2 llekkrktpldlenpeherlLkelwsalypdepeinst....................ksrisekWkklGFqgedPatDFrgtGlLgLenLlyfaenhe 80 
                 ll+k++++p+dle+p+h+r+Lk ++ a+ p ++e+  +                    +++++ekW++lGFq+e+Pa++F  +G+Lg+++L++++++h+
  EEA22287.1 231 LLRKWKNVPVDLEKPDHRRALKGIHLASNPAKKESGGSsaggssensatagendikksRKHNPEKWRRLGFQSESPAAEFHEMGFLGMMDLTDYVRKHQ 329
                 699**************************9999998779************************************************************ PP

  ELMO_CED12  81 eefqkllsessrrpseeeypfavasinvtslllelleiektdeed.eeeqkdklktnntkllssnlnafeelfsvlfllfdslWkekkatimdfnkv 176
                 + fqk+l+e+s +p+e+++p+a+as++vts+l+e++e+ek+  +d +++   ++++n++k +++ l ++++++++ +++f++lWk++ a++ df+k+
  EEA22287.1 330 DDFQKMLLEQSAKPAEQRCPIARASLAVTSVLYEHFEVEKSATDDaKSYLVLESRSNFDKVFKPLLLHWSRIHVASLQAFFRLWKATSAEVADFDKI 426
                 **************************************999999966888999999****************************************8 PP

>> PH_12  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.0   0.2   2.3e-37   8.4e-34       1     134 []     497     693 ..     497     693 .. 0.87

  Alignments for each domain:
  == domain 1  score: 117.0 bits;  conditional E-value: 2.3e-37
       PH_12   1 vkeqRincLleGawfpk...............pgesgkrekkkwrfvkLspnrkvLhygdfeekspqdpsleeltekidlsdisevksgkeaphskesg 84 
                 vkeqRi+cLl+Gawfp+                + s++++++ + +v+Ls+nr++Lh+ df+  +++ p+l++l++kidls +s+v+s+++a+++++sg
  EEA22287.1 497 VKEQRIRCLLQGAWFPNepvssprpedsspikTADSKNKQSQGYKYVQLSHNRRYLHFSDFDAIKETAPALDSLSNKIDLSIVSSVVSNVSASSDDSSG 595
                 89***************998888888888764335666666***************************************************9999666 PP

       PH_12  85 kssssl...............skksssklsfslitl.................................skekellelvasseseaaeWlDGLsmLlg 134
                 ++ +++               s++s++++s ++it+                                 + e +ll+l ++++s a+eWlDGL+mLl+
  EEA22287.1 596 STIKTTpgngnssslhpppgtSSSSATTTSSTKITIhgyaptiasssgpkslattnkesghtrtgskttQREIPLLTLRPQNHSIASEWLDGLLMLLN 693
                 666655667777777788888777777777777777899999999999999999999999999999999***************************97 PP

>> DUF3361  Domain of unknown function (DUF3361)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.4   0.0   9.1e-19   3.2e-15       2     132 ..      37     184 ..      36     207 .. 0.86

  Alignments for each domain:
  == domain 1  score: 56.4 bits;  conditional E-value: 9.1e-19
     DUF3361   2 FAqeFisrdGlkllvkiveegkesgeilayaLtafleLmdhgivsWdtlsdeFikkiasivnksaadasilqrslaiLesivlnss............. 87 
                 FA+ Fi ++Gl+ l  ++ +   +g++lay Lt+f  L++    +W+ +++e +++i++ + ++   ++il+ ++a+L siv   +             
  EEA22287.1  37 FADIFIAEGGLSKLRYLILTT--TGNTLAYSLTSFARLLEV-DKGWEFVDEEVVERIVHLIVTH-PLVNILRGAMAMLVSIVSHPHiprseseqsppee 131
                 *******************98..9****************9.89*******************9.559****************999999999999998 PP

     DUF3361  88 ...elyelvekevt.....lesLiehLqssnqeiqtnalaLlnALllkaddsk 132
                      +  ++ ++      le L+++L+s+++ ++ nal L+n+L++ +  ++
  EEA22287.1 132 kevYGFRALKPAIDkhpqfLEMLVSRLSSADHALCANALQLINSLMRDSITND 184
                 766225555555556666899*************************9875443 PP

>> DUF3552  Domain of unknown function (DUF3552)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.5   3.5e-05      0.13     118     174 ..     443     500 ..     441     504 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 3.5e-05
     DUF3552 118 keqsleekeeeleelveeqrqeLe.risgLtkeeAkeilleeveeelkheaAkmikei 174
                 ++++++  eeel++   ++ +eL+ ++ +Lt e+A  + l++v++el+hea + +ke 
  EEA22287.1 443 RTKDVQDVEEELDDFEYQRLRELQmELLELTYEDAWGQHLRQVRDELQHEALQFVKEQ 500
                 578999*****************868*************************9999986 PP

>> PCNP  PEST, proteolytic signal-containing nuclear protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.2   2.9e-05       0.1      12     100 ..     256     363 ..     245     370 .. 0.84
   2 ?   -2.6   0.5       2.3   8.2e+03      27      61 ..     593     625 ..     570     658 .. 0.45

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 2.9e-05
        PCNP  12 tktvssskksnrkesssrsaekrsaeeeeeskeappapskisKigfslskqaakkk...................kpisiklgasskPkeeapklaakk 91 
                   +++ +k+s+ +++  +s+++ +a e++ +k+ + +p k  ++gf+ +++aa+ +                      ++ l++s+kP+e+   +a   
  EEA22287.1 256 LASNPAKKESGGSSAGGSSENSATAGENDIKKSRKHNPEKWRRLGFQSESPAAEFHemgflgmmdltdyvrkhqdDFQKMLLEQSAKPAEQRCPIARAS 354
                 4455566677778888888888999999999999*****************9988899*************99977778999*************9999 PP

        PCNP  92 ptvaavfne 100
                 ++v +v+ e
  EEA22287.1 355 LAVTSVLYE 363
                 999999766 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 2.3
        PCNP  27 ssrsaekrsaeeeeeskeappapskisKigfslsk 61 
                 ss s+ k++  + ++s+ +p  p   s  + ++++
  EEA22287.1 593 SSGSTIKTTPGNGNSSSLHP-PPGTSSSSA-TTTS 625
                 33334444444444333322.222222222.2222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (752 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       714  (0.0398237); expected 358.6 (0.02)
Passed bias filter:                      479  (0.0267165); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.64u 0.25s 00:00:00.89 Elapsed: 00:00:00.41
# Mc/sec: 5567.82
//
Query:       EEA22288.1  [L=369]
Description: tartrate dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.1e-86  288.1   0.0    1.1e-85  287.8   0.0    1.0  1  Iso_dh    Isocitrate/isopropylmalate dehydrogenase


Domain annotation for each model (and alignments):
>> Iso_dh  Isocitrate/isopropylmalate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  287.8   0.0   6.3e-90   1.1e-85       2     348 .]      14     356 ..      13     357 .. 0.96

  Alignments for each domain:
  == domain 1  score: 287.8 bits;  conditional E-value: 6.3e-90
                 EEEEEESTTHHHHHHHHHHHHHHHHHHHT.-EEEEEE---THHHHHHHSSSS-HHHHHHHHHSSEEEEEE---CSSSSSSHHHHH.HHHHHHTTEEEEE CS
      Iso_dh   2 iallegdgiGpevveaalkvlkaakekag.lelefeevdvGgaaidetgeplpeetleaikeadvvllgavgtpkekevrpengL.laLrkeldlfanl 98 
                 ia ++ dgiGpev++a +  l+a+++  +   l+f ++d + +++++tg+ +p+  le++k+ d++l+gavg p+  ++ +  gL la+ + l+ +an+
  EEA22288.1  14 IASIPADGIGPEVIAAGITALQALANTLKtFTLDFTHYDWSSETYKRTGKYIPDGDLEQLKKHDAILFGAVGAPDVPDHISLWGLrLAICQPLQQYANV 112
                 899********************887666599*******************************************9999999998789*********** PP

                 EEEE-BCCTTCCSSBTHHHHCT-EEEEEEE-SSCGGCSSEEEEETTG.GGGEEEEEEEEEHHHHHHHHHHHHHHHHHTTTSEEEEEESTTTTHHHH.HH CS
      Iso_dh  99 rpvkvfeklkvksplkrevveevdlvivReltggiYfgeekekkgsifteevavdtklyseeeieriaraafelAlkrgkkkvtlvdKanvlksse.lw 196
                 rp kv+   + +spl++   ++++ vi+Re+ +g Y+g+    ++   + e + +t+ +s+++ieri+++afe+A++r++k +t+v+K+n  +    lw
  EEA22288.1 113 RPTKVL--RGTQSPLRNCATGDLNWVIIRENSEGEYAGQGGRSHQG-RPWEIGTETAIFSRHGIERIMHFAFETAQQRPRKLLTVVTKSNAQRNGMvLW 208
                 ******..89******988888*****************9988886.699********************************************99788 PP

                 HHHHHHHHCCTTTTSEEEEEEHHHHHHHHHHSGGGGSEEEE-HHHHHHHHHHHHHHTTSGCC-EEEEEET..SS-EEEEESS---CCCTTSS-S-THHH CS
      Iso_dh 197 rkiveevaeeeypdielehqlvDsaamqlvkspkqfdVivtkNlfGDilSDeaaalvGslGllpSaslge..kkvaifEavHGsapdiagkdkaNpiav 293
                  ++++ v + ++pd++++++lvD++++++v +p++ d iv++Nl  DilSD+aaal Gs+G++p ++l +  ++  +fE++HGsa di g ++aNp+++
  EEA22288.1 209 DEVAKAVSQ-DFPDVTVDKMLVDAMTARMVLKPETLDTIVATNLHADILSDLAAALAGSIGIAPTSNLDPtrQNPSMFEPIHGSAFDITGMGIANPVGT 306
                 888888887.***********************************************************99999************************* PP

                 HHHHHHHHHHTTT-HHHHHHHHHHHHHHHHHTSCCHHHCTTSTCCCHHHHHHHHH CS
      Iso_dh 294 ilSaalmLryslgleeaAdkiekAvekvleagivTkDlageaakevstsefgdav 348
                    a+ mL+  lg+++aA+k+ + ve+v e+g++T+Dl+g+a    +t+e+++av
  EEA22288.1 307 FWTAVEMLNW-LGEKDAAAKLLDCVENVCEQGVLTRDLGGKA----TTKEVTEAV 356
                 **********.*******************************....999999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (369 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       324  (0.0180713); expected 358.6 (0.02)
Passed bias filter:                      300  (0.0167327); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2604.40
//
Query:       EEA22289.1  [L=594]
Description: protein phosphatase type 1 complex subunit Hex2/Reg1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-11   43.3   4.8    4.4e-11   42.4   4.8    1.5  1  DUF1752   Fungal protein of unknown function (DUF1752)


Domain annotation for each model (and alignments):
>> DUF1752  Fungal protein of unknown function (DUF1752)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.4   4.8   2.5e-15   4.4e-11       1      28 []     164     191 ..     164     191 .. 0.98

  Alignments for each domain:
  == domain 1  score: 42.4 bits;  conditional E-value: 2.5e-15
     DUF1752   1 lWkyytkkkkdlpngeRLENlSWRlWnk 28 
                 +W+y+++ ++ ++ng RLEN+SWR+W+k
  EEA22289.1 164 SWRYVVTRRDRYSNGVRLENASWRTWAK 191
                 8*************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (594 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       725  (0.0404373); expected 358.6 (0.02)
Passed bias filter:                      357  (0.0199119); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.75u 0.35s 00:00:01.10 Elapsed: 00:00:00.57
# Mc/sec: 3122.79
//
Query:       EEA22290.1  [L=192]
Description: RNA binding protein Tma22, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.4e-24   85.1   0.3    8.3e-24   83.9   0.3    1.7  1  SUI1           Translation initiation factor SUI1
  ------ inclusion threshold ------
      0.011   15.5   0.7      0.015   15.0   0.7    1.1  1  RNA_pol_Rpc82  RNA polymerase III subunit RPC82


Domain annotation for each model (and alignments):
>> SUI1  Translation initiation factor SUI1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.9   0.3   9.2e-28   8.3e-24       2      73 ..      97     170 ..      96     174 .. 0.92

  Alignments for each domain:
  == domain 1  score: 83.9 bits;  conditional E-value: 9.2e-28
        SUI1   2 kpkihirleqrggrKkvTtvsgleafgidlkklakelkkkfacsgsvvk..dggeeiqvQGdqrkkvaelLtek 73 
                  +ki i++ +r++rK vT+v gle fg+dlkk+akel kkfa+++sv+k   g eei+vQGd+++++ e+L++ 
  EEA22290.1  97 SSKIIIKRVERNKRKFVTVVIGLEQFGLDLKKVAKELGKKFATGSSVTKsaAGAEEITVQGDVSDDLFEWLVDI 170
                 579********************************************9954335*****************975 PP

>> RNA_pol_Rpc82  RNA polymerase III subunit RPC82
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.0   0.7   1.7e-06     0.015       9     116 ..      38     127 ..      37     133 .. 0.77

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.7e-06
                    TSSEEESSSTTTS-HHHHHHHHHHHTHTTSSSSSSSSTHHHHHHHHHHHHHHHHHHHHHHHSGT....T..TTCETSSSSSEE......E-TSSEE CS
  RNA_pol_Rpc82   9 agflqrvpslhfrpiedlwnalyeeelkktprssttseikkkaeakekiktelrdlresseslkkkegrstadstsngtarKrrketealdpglvl 104
                    +++lq+ ++       dl+++ly ee  + +  st+s +++++ ak+ +k e + l +++ ++++   ++    ++    +Kr          +++
     EEA22290.1  38 EEWLQKTHP-------DLHEQLYSEEALNAN-LSTLSITAREKAAKDAAKKEAKALQAETRDAERLASSK--IIIKRVERNKR--------KFVTV 115
                    579999999.......*******99999998.9*****************************99433333..33333333333........34667 PP

                    EE-SHHHHHHHH CS
  RNA_pol_Rpc82 105 riNlerflvhlR 116
                     i le+f  +l+
     EEA22290.1 116 VIGLEQFGLDLK 127
                    777777766665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (192 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1390  (0.077528); expected 358.6 (0.02)
Passed bias filter:                      636  (0.0354733); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.31s 00:00:00.82 Elapsed: 00:00:00.48
# Mc/sec: 1192.62
//
Query:       EEA22291.1  [L=181]
Description: RNA binding protein Tma22, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.9e-24   85.4   0.3    7.2e-24   84.1   0.3    1.7  1  SUI1           Translation initiation factor SUI1
     0.0096   15.7   0.7      0.013   15.2   0.7    1.2  1  RNA_pol_Rpc82  RNA polymerase III subunit RPC82


Domain annotation for each model (and alignments):
>> SUI1  Translation initiation factor SUI1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.1   0.3   8.1e-28   7.2e-24       2      73 ..      86     159 ..      85     163 .. 0.92

  Alignments for each domain:
  == domain 1  score: 84.1 bits;  conditional E-value: 8.1e-28
        SUI1   2 kpkihirleqrggrKkvTtvsgleafgidlkklakelkkkfacsgsvvk..dggeeiqvQGdqrkkvaelLtek 73 
                  +ki i++ +r++rK vT+v gle fg+dlkk+akel kkfa+++sv+k   g eei+vQGd+++++ e+L++ 
  EEA22291.1  86 SSKIIIKRVERNKRKFVTVVIGLEQFGLDLKKVAKELGKKFATGSSVTKsaAGAEEITVQGDVSDDLFEWLVDI 159
                 579********************************************9954335*****************985 PP

>> RNA_pol_Rpc82  RNA polymerase III subunit RPC82
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.7   1.5e-06     0.013       9     116 ..      27     116 ..      26     122 .. 0.77

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1.5e-06
                    TSSEEESSSTTTS-HHHHHHHHHHHTHTTSSSSSSSSTHHHHHHHHHHHHHHHHHHHHHHHSGT....T..TTCETSSSSSEE......E-TSSEE CS
  RNA_pol_Rpc82   9 agflqrvpslhfrpiedlwnalyeeelkktprssttseikkkaeakekiktelrdlresseslkkkegrstadstsngtarKrrketealdpglvl 104
                    +++lq+ ++       dl+++ly ee  + +  st+s +++++ ak+ +k e + l +++ ++++   ++    ++    +Kr          +++
     EEA22291.1  27 EEWLQKTHP-------DLHEQLYSEEALNAN-LSTLSITAREKAAKDAAKKEAKALQAETRDAERLASSK--IIIKRVERNKR--------KFVTV 104
                    579999999.......*******99999998.9*****************************99433333..33333333333........34667 PP

                    EE-SHHHHHHHH CS
  RNA_pol_Rpc82 105 riNlerflvhlR 116
                     i le+f  +l+
     EEA22291.1 105 VIGLEQFGLDLK 116
                    777777766665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1254  (0.0699426); expected 358.6 (0.02)
Passed bias filter:                      537  (0.0299515); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 1308.32
//
Query:       EEA22292.1  [L=478]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    0.00089   19.6   0.5     0.0025   18.2   0.5    1.8  1  Snapin_Pallidin  Snapin/Pallidin
     0.0089   15.4   2.9     0.0089   15.4   2.9    2.3  3  GAS              Growth-arrest specific micro-tubule binding
  ------ inclusion threshold ------
      0.013   13.7   3.6      0.023   12.9   3.6    1.3  1  HOOK             HOOK protein
      0.032   14.5   1.1       0.17   12.2   0.3    2.4  2  BLOC1_2          Biogenesis of lysosome-related organelles co
       0.12   12.6   1.9       0.16   12.2   0.1    2.2  2  XhlA             Haemolysin XhlA
       0.13   12.7   3.6       0.18   12.3   0.9    2.5  2  DUF16            Protein of unknown function DUF16
       0.14   12.1   0.0       0.14   12.1   0.0    2.6  3  GRA6             Granule antigen protein (GRA6)
       0.16   11.7   1.7        1.6    8.4   0.3    2.8  3  RPW8             Arabidopsis broad-spectrum mildew resistance
       0.34   11.3   4.2       0.16   12.4   0.6    2.4  3  FlaC_arch        Flagella accessory protein C (FlaC)
        1.2    9.3   7.4          4    7.6   7.4    1.9  1  UPF0561          Uncharacterised protein family UPF0561


Domain annotation for each model (and alignments):
>> Snapin_Pallidin  Snapin/Pallidin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.5   1.4e-06    0.0025      15      89 ..     262     335 ..     255     336 .. 0.89

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 1.4e-06
  Snapin_Pallidin  15 ldeldeklkelrqsQeeLleqldrlnekLkeleeaqe.aevlpdlkeyakKLvnikkrmsslnerlqklkkRaekL 89 
                      l  + ++++el +s   L+e+ +  ++ L+  +++++  + ++++++ ++++ ++++rm++ ++++++l +R++k+
       EEA22292.1 262 LYSTIHTFQELVDSSGTLHETFQHDTSTLE--SDVHKkLSEFAKFDPQRQRIDELEQRMKAGKQKMENLGERLDKV 335
                      66778899*********************8..566666677********************************986 PP

>> GAS  Growth-arrest specific micro-tubule binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1       0.7   1.3e+03      55     120 ..     198     264 ..     192     285 .. 0.59
   2 !   15.4   2.9     5e-06    0.0089      66     139 ..     283     356 ..     267     361 .. 0.89
   3 ?   -2.2   0.0       1.2   2.2e+03     135     168 ..     418     451 ..     396     462 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.7
         GAS  55 enkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkele.kelkdlkwehevleqrfekvek 120
                 +  +l+  + k  +  e L  + ++ ek  + l++  a + +l  +  ++l + + +l +r++++ +
  EEA22292.1 198 QRLSLTTMVGKEIKTAEDLSLARQEREKGEEMLRSKLASIGTLAtDITRRLDYTYYNLLERISTLYS 264
                 5555555556666666666666666666666666555555444314445666666666666666655 PP

  == domain 2  score: 15.4 bits;  conditional E-value: 5e-06
         GAS  66 aeeeveeLrkqlknyekdkqslknlkarlkelekelkdlkwehevleqrfekvekerdelykkfeaaiqevqqk 139
                  +++   L+ ++ +  +++++++ +++r+ ele+ +k+ k++ e+l +r++kv ke++ ++ +  +    v q+
  EEA22292.1 283 FQHDTSTLESDVHKKLSEFAKFDPQRQRIDELEQRMKAGKQKMENLGERLDKVRKEIEGWEMREGEWQARVTQR 356
                 577888999999999*******************************************9999988877777776 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 1.2
         GAS 135 evqqktglknllLekklkalqeelEkkeaqleev 168
                 +v  kt lk+ lL k  +  +e++++ e  ++e+
  EEA22292.1 418 DVDLKTFLKSPLLMKSTTDSEETIDHHESPITET 451
                 7888999999999999999999999999888876 PP

>> HOOK  HOOK protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   3.6   1.3e-05     0.023     495     594 ..     246     345 ..     208     349 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.3e-05
        HOOK 495 neLetenrlanqrileLeaqveelqkalqeqgskaed....ssllkkkleehleklkevqeelqkkkeqleelepklssnkqkieeleeaLkkkdedlk 589
                  +L+       +ri+ L + +   q+  +++g+ +e+    +s+l+++++++l +  + + +    ++ ++ele+++++ kqk+e+l e L k  ++++
  EEA22292.1 246 RRLDYTYYNLLERISTLYSTIHTFQELVDSSGTLHETfqhdTSTLESDVHKKLSEFAKFDPQ----RQRIDELEQRMKAGKQKMENLGERLDKVRKEIE 340
                 456666666789*********99999999999988872222555555555555555555555....566***********************9999888 PP

        HOOK 590 ameer 594
                   e r
  EEA22292.1 341 GWEMR 345
                 77765 PP

>> BLOC1_2  Biogenesis of lysosome-related organelles complex-1 subunit 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0      0.97   1.7e+03      43      76 ..     213     246 ..     207     267 .. 0.74
   2 ?   12.2   0.3   9.4e-05      0.17      27      92 ..     271     340 ..     258     341 .. 0.82

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.97
     BLOC1_2  43 aaslekkleklnekyeelqpylqqidqiekqvte 76 
                 a++l+   ++ ++ +e l+++l +i  + +++t+
  EEA22292.1 213 AEDLSLARQEREKGEEMLRSKLASIGTLATDITR 246
                 6777777888888888999999999999998874 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 9.4e-05
     BLOC1_2  27 klNeaasekykklkdvaaslekkleklnekyeelqpylqqidqiekqvt....eLeeavseLDeyskeLE 92 
                 +l  ++ +  +  ++ ++ le++++k  ++ ++++p+ q+id++e++ +    ++e++ ++LD+  ke+E
  EEA22292.1 271 ELVDSSGTLHETFQHDTSTLESDVHKKLSEFAKFDPQRQRIDELEQRMKagkqKMENLGERLDKVRKEIE 340
                 55555666667778889999****999999*****************9533338*********9999988 PP

>> XhlA  Haemolysin XhlA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.1   8.9e-05      0.16      13      46 ..     304     337 ..     299     341 .. 0.88
   2 ?   -3.5   0.1       7.2   1.3e+04      10      25 ..     438     453 ..     434     461 .. 0.62

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 8.9e-05
        XhlA  13 ldnleervdkleekaaeaeekiknleedlkkles 46 
                  d   +r+d+le+++   ++k +nl e+l+k  +
  EEA22292.1 304 FDPQRQRIDELEQRMKAGKQKMENLGERLDKVRK 337
                 566789***********************99765 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 7.2
        XhlA  10 etkldnleervdklee 25 
                 e+ +d +e+ +++ + 
  EEA22292.1 438 EETIDHHESPITETDT 453
                 5666777765555444 PP

>> DUF16  Protein of unknown function DUF16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.1       1.4   2.5e+03      71     100 ..     220     249 ..     193     251 .. 0.61
   2 ?   12.3   0.9    0.0001      0.18      17      94 ..     261     341 ..     254     358 .. 0.66

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 1.4
                 HHHHHH.......HHHHHHHHHHHHHHHHH CS
       DUF16  71 qkaqgeelnkvdetleliletLqkinkRlD 100
                  + +++  + + + l +i    ++i  RlD
  EEA22292.1 220 RQEREKGEEMLRSKLASIGTLATDITRRLD 249
                 222222223667788888888899999998 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 0.0001
                 TTB-BHHHHHHB-..BHHHHHHHHHHHH...HHHHHH.HH..HHHHHHHHHHHHHHHHHHHHH.......HHHHHHHHHHH CS
       DUF16  17 teYVTrkqlnefkdsnkqrLkkieakvdklgeqinkl.eq..kvekqgekikelkveqkaqgeelnkvdetleliletLqk 94 
                 t Y T + ++e  ds  +  + +++  ++l+  ++k   +  k + q ++i+el++++ka ++++++++e l+ + + ++ 
  EEA22292.1 261 TLYSTIHTFQELVDSSGTLHETFQHDTSTLESDVHKKlSEfaKFDPQRQRIDELEQRMKAGKQKMENLGERLDKVRKEIEG 341
                 668888888888888555555555555555555443302211455677777777777777777777777777777666655 PP

>> GRA6  Granule antigen protein (GRA6)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.5       0.7   1.3e+03     100     133 ..      67     101 ..      28     127 .. 0.56
   2 ?   -1.3   0.4      0.97   1.7e+03      78     111 ..     177     210 ..     162     241 .. 0.61
   3 ?   12.1   0.0   7.8e-05      0.14      99     184 ..     302     389 ..     263     398 .. 0.67

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.7
        GRA6 100 dvdPfpvlidegkse.argPsleerieeqddrrrp 133
                 d++P +  ++  +++  +  s   r  e+++ +r+
  EEA22292.1  67 DLEPASSNEKTANNNnSNDNSNSSRKSENQKSHRY 101
                 33333333332222102222333333333333333 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.97
        GRA6  78 lgGgqgdslaeaddetsdvaegdvdPfpvlideg 111
                  +G++g sl   ++  s++a   +   +++ +e 
  EEA22292.1 177 NSGSRGTSLVVTEEGDSEAASQRLSLTTMVGKEI 210
                 3688888888888888888766555555544443 PP

  == domain 3  score: 12.1 bits;  conditional E-value: 7.8e-05
        GRA6  99 gdvdPfpvlidegkseargPs.leerieeq.ddrrrpssvqeaqakvsskraqkrhrliGavvlaasvalltafflrrsgrrapgePr 184
                 +  dP    ide ++  ++   + e + e+ d+ r+     e        r  +r r++Ga v++ ++ ++ a+ lr +   ++g P 
  EEA22292.1 302 AKFDPQRQRIDELEQRMKAGKqKMENLGERlDKVRKEIEGWEMREGEWQARVTQRLRVLGAFVVSLALVVIVAYVLRSTPTTSTGTPL 389
                 456777777776554444333244555444155577777778888888889999************999999****999999999986 PP

>> RPW8  Arabidopsis broad-spectrum mildew resistance protein RPW8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0      0.18   3.3e+02      40      70 ..     255     285 ..     232     296 .. 0.80
   2 ?    8.4   0.3   0.00089       1.6      41      76 ..     301     336 ..     283     346 .. 0.73
   3 ?   -2.1   0.0       1.5   2.7e+03     103     127 ..     417     441 ..     412     451 .. 0.84

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.18
        RPW8  40 tleritPvvkeieklnkeldrpreeieeLkk 70 
                  leri+++   i ++++ +d+    +e +++
  EEA22292.1 255 LLERISTLYSTIHTFQELVDSSGTLHETFQH 285
                 489999999****999999998888877765 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.00089
        RPW8  41 leritPvvkeieklnkeldrpreeieeLkklLekae 76 
                   +  P +++i++l+++++  ++++e+L ++L+k  
  EEA22292.1 301 FAKFDPQRQRIDELEQRMKAGKQKMENLGERLDKVR 336
                 456678888888888888888888888888887754 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 1.5
        RPW8 103 Lekslrkfvqvelqvqqvrdikell 127
                 ++ +l+ f +  l +++++d+ e++
  EEA22292.1 417 VDVDLKTFLKSPLLMKSTTDSEETI 441
                 678999999999****999999876 PP

>> FlaC_arch  Flagella accessory protein C (FlaC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       4.4   7.8e+03      10      11 ..     274     275 ..     256     296 .. 0.47
   2 ?   12.4   0.6   9.1e-05      0.16       1      31 [.     310     340 ..     310     345 .. 0.95
   3 ?   -2.6   0.1       4.4   7.8e+03      24      34 ..     392     402 ..     390     404 .. 0.55

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 4.4
   FlaC_arch  10 sk 11 
                 ++
  EEA22292.1 274 DS 275
                 22 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 9.1e-05
   FlaC_arch   1 ridelEnklsklsteletvkkeneelsksve 31 
                 ridelE++++  + ++e++ + +++++k++e
  EEA22292.1 310 RIDELEQRMKAGKQKMENLGERLDKVRKEIE 340
                 9*****************************9 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 4.4
   FlaC_arch  24 eelsksveelk 34 
                 ++l++ +e+l 
  EEA22292.1 392 QDLNSRIEMLS 402
                 55566666665 PP

>> UPF0561  Uncharacterised protein family UPF0561
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   7.4    0.0022         4      11      98 ..       6      97 ..       2     105 .. 0.80

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0022
     UPF0561 11 kpggrldmshgf...lrhirrnqiarddydkevkqakekqrrrhtttprrprrpdlqvylprsrdgsepgsnaeaeesnesss.steaettg 98
                kp grl  s  f   ++h  r +++r    ++ +   + q r  ++  r+p    l v +      s +  +a+ ++sn+ s  s ++e++ 
  EEA22292.1  6 KPSGRLSTSRTFpvnIHHRHRSEVTRPSNHNQSQSQNQSQTRNGAPEERQPWPRRLFVDTSDLEPASSNEKTANNNNSNDNSNsSRKSENQK 97
                9**********988889*********998888877888888888999999887788888888888888888888888877554155666664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (478 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1911  (0.106587); expected 358.6 (0.02)
Passed bias filter:                      756  (0.0421663); expected 358.6 (0.02)
Passed Vit filter:                        94  (0.0052429); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.74u 0.28s 00:00:01.02 Elapsed: 00:00:00.43
# Mc/sec: 3302.04
//
Query:       EEA22293.1  [L=116]
Description: rRNA processing protein CgrA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.4e-34  117.1  31.1      5e-34  116.9  31.1    1.0  1  Cgr1           Cgr1 family
  ------ inclusion threshold ------
        0.7    9.4   5.8       0.78    9.3   5.8    1.0  1  VIR_N          Virilizer, N-terminal
        5.8    6.6  14.0        6.1    6.6  14.0    1.0  1  RR_TM4-6       Ryanodine Receptor TM 4-6
        6.5    5.4   7.4        6.7    5.4   7.4    1.0  1  Presenilin     Presenilin


Domain annotation for each model (and alignments):
>> Cgr1  Cgr1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.9  31.1   1.1e-37     5e-34       3     107 ..      17     115 ..      15     116 .] 0.98

  Alignments for each domain:
  == domain 1  score: 116.9 bits;  conditional E-value: 1.1e-37
        Cgr1   3 gkrvsGksWkteKkafrsksskkkkkkkkswekrqekrkkakaiKklekeLkdekeaerqrrieaikerrkakeEkeRleelaakmhakkveRlkrrek 101
                 g+r++Gk+W+t+Kk+fr++++       ks+ekr ++r++++a+K++eke+kdekeaerqr+i+aik+rr+ak+EkeR+e++a+kmh+k+veR+kr+ek
  EEA22293.1  17 GMRKNGKNWRTPKKPFRPTAG------LKSYEKRLQDRNNMAAMKEREKEMKDEKEAERQRHIQAIKDRRAAKAEKERYEKMAEKMHKKRVERRKRKEK 109
                 89******************9......89********************************************************************** PP

        Cgr1 102 Rnkklk 107
                 Rnk+l+
  EEA22293.1 110 RNKLLN 115
                 ****99 PP

>> VIR_N  Virilizer, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   5.8   0.00017      0.78     160     250 ..      24     109 ..       5     115 .. 0.58

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00017
       VIR_N 160 eprePrtpelipaytgnvastpPpdddeeedaavpetveeekeensekredyleeesPeertslkaeekdseaereeresseeierdeees 250
                 ++r P++p      t+ + s++   +d ++ aa++e ++e k+e++ +r+ ++++++  +r   kae++  e++ e+ ++++   r++ e+
  EEA22293.1  24 NWRTPKKP---FRPTAGLKSYEKRLQDRNNMAAMKEREKEMKDEKEAERQRHIQAIKD-RR-AAKAEKERYEKMAEKMHKKRVERRKRKEK 109
                 45555555...23344555555555555555777777777888888888888888876.55.55555555565555554444444444332 PP

>> RR_TM4-6  Ryanodine Receptor TM 4-6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6  14.0    0.0014       6.1      65     146 ..      33     111 ..      11     116 .] 0.47

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.0014
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXX..........XXXXXXXXX CS
    RR_TM4-6  65 kseagLgDlseteaeesptpelkkklaeeeeaeeekeeeeepeaeaeekadaengekeekekekeeeekeseeeeeekkkkk 146
                  ++agL    +    +++ +++k++++   e ++eke+e++++ +a++++ a + eke+ ek  e+ +k++ e+ ++k+k++
  EEA22293.1  33 RPTAGLKSYEKRLQDRNNMAAMKEREK---EMKDEKEAERQRHIQAIKDRRAAKAEKERYEKMAEKMHKKRVERRKRKEKRN 111
                 455555555555555554444444333...2344444444444444455555555555555544444444444444444333 PP

>> Presenilin  Presenilin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   7.4    0.0015       6.7     236     294 ..      47     105 ..       6     115 .. 0.37

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.0015
  Presenilin 236 eeeeeaekkkeeasesskeeeseeesseksaqsseseeeseeesseaessaeesseeke 294
                 ++++ a  k++e+++++++e++++++ ++++ +++ ++e+e+ ++ ae+ ++++ e+++
  EEA22293.1  47 DRNNMAAMKEREKEMKDEKEAERQRHIQAIKDRRAAKAEKERYEKMAEKMHKKRVERRK 105
                 11111222222222222222222222222222221111111111111111111111111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (116 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3224  (0.17982); expected 358.6 (0.02)
Passed bias filter:                      751  (0.0418874); expected 358.6 (0.02)
Passed Vit filter:                       112  (0.00624686); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.31s 00:00:00.83 Elapsed: 00:00:00.48
# Mc/sec: 731.60
//
Query:       EEA22294.1  [L=321]
Description: mitochondrial ornithine carrier protein AmcA/Ort1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.3e-64  212.5   1.4    9.2e-22   76.8   0.1    3.0  3  Mito_carr        Mitochondrial carrier protein
     0.0026   17.0   0.4        4.1    6.5   0.0    3.5  3  Serine_protease  Gammaproteobacterial serine protease


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.1   0.0   1.4e-24   1.3e-20       4      95 ..      28     118 ..      25     120 .. 0.93
   2 !   60.6   0.1   1.1e-20     1e-16       4      95 ..     127     216 ..     124     218 .. 0.92
   3 !   76.8   0.1     1e-25   9.2e-22       3      93 ..     230     320 ..     228     321 .] 0.96

  Alignments for each domain:
  == domain 1  score: 73.1 bits;  conditional E-value: 1.4e-24
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCT CS
   Mito_carr   4 svlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlllk 95 
                 ++lk++  G++ag++++++ +P+d++K+rlq+q++    ++ ++ ld++++ ++++G+r+lyrG+++ l + a++++  f++y   k+ll+ 
  EEA22294.1  28 TALKDVTFGSIAGIAGKCIEYPFDTIKVRLQSQPHGVPLRY-TGPLDCFRQSIHSDGFRSLYRGISAPLAGAAVENSSLFFSYRIAKNLLQS 118
                 578999*****************************988755.55********************************************9975 PP

  == domain 2  score: 60.6 bits;  conditional E-value: 1.1e-20
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCT CS
   Mito_carr   4 svlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlllk 95 
                 ++   ll+G+l+ga+++++ tP+++vK+++q+ +++++ +   + l+++ ++++++G+ gl+rG + +l+r +  sa++f++ye +  ++ +
  EEA22294.1 127 PYSGLLLSGALSGAFTSVLLTPIELVKCKMQVPSTTTSVKP--GPLKIIATVFRHHGMFGLWRGQMGTLIRETGGSAAWFGSYEAVSAVFRR 216
                 667789***************************99988754..49*****************************************999876 PP

  == domain 3  score: 76.8 bits;  conditional E-value: 1e-25
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   3 lsvlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrll 93 
                 l v++++laG++ag+   ++ +P d++K r+qt++ s  +s +++++ v k+++++eGl+glyrG+++++ r+ap+sa  f++ye l +++
  EEA22294.1 230 LAVWQQMLAGATAGVSYNFIFYPADTIKSRMQTEEISVLSSANRSFWTVGKSVWQHEGLKGLYRGCGITVARSAPSSAFIFSIYEGLSHYF 320
                 679**********************************99999899*****************************************99987 PP

>> Serine_protease  Gammaproteobacterial serine protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.5   0.0   0.00045       4.1      20      64 ..      46     100 ..      30     106 .. 0.74
   2 ?    1.6   0.0     0.014   1.2e+02     177     205 ..     132     160 ..     127     179 .. 0.80
   3 !    4.6   0.1    0.0018        16     175     269 ..     234     320 ..     231     321 .] 0.53

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.00045
  Serine_protease  20 ltsPfkalLtnlqkdgsvlpsaysgG...........lfralYrGflayalagskr 64 
                      +  Pf ++ ++lq +  ++p  y g             fr+lYrG++a  lag ++
       EEA22294.1  46 IEYPFDTIKVRLQSQPHGVPLRYTGPldcfrqsihsdGFRSLYRGISA-PLAGAAV 100
                      566888888888888888887774445554444444459********9.9999876 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.014
  Serine_protease 177 llaGalsGviAtvlttifnsykDkkllas 205
                      ll+GalsG+  +vl t++ + k k  + s
       EEA22294.1 132 LLSGALSGAFTSVLLTPIELVKCKMQVPS 160
                      789***********999988887766554 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.0018
  Serine_protease 175 nkllaGalsGviAtvlttifnsykDkkllaskvengrllt.aspftllkqlkshvke..glkealktfvkvnalkevliRspltaliFaiifgv 265
                      +++laGa++Gv   ++ ++  + k      s+++  ++    s+   +  + + v++  glk     +        v+  +p +a iF+i  g+
       EEA22294.1 234 QQMLAGATAGVSYNFIFYPADTIK------SRMQTEEISVlSSANRSFWTVGKSVWQheGLKGLYRGCGI-----TVARSAPSSAFIFSIYEGL 316
                      789999999998888888865544......4443333322033334455555555543344444433333.....3444455666677776666 PP

  Serine_protease 266 dell 269
                       +++
       EEA22294.1 317 SHYF 320
                      6665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (321 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       292  (0.0162865); expected 358.6 (0.02)
Passed bias filter:                      266  (0.0148363); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.23s 00:00:00.72 Elapsed: 00:00:00.43
# Mc/sec: 2256.05
//
Query:       EEA22295.1  [L=420]
Description: cytidine deaminase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.2e-12   46.7   0.0    4.6e-12   45.7   0.0    1.5  1  dCMP_cyt_deam_1  Cytidine and deoxycytidylate deaminase zinc-
    7.5e-05   22.9   3.9     0.0037   17.5   0.2    3.0  3  dCMP_cyt_deam_2  Cytidine and deoxycytidylate deaminase zinc-
     0.0054   16.4   1.4        1.4    8.5   0.4    2.8  1  LmjF365940-deam  A distinct subfamily of CDD/CDA-like deamina
  ------ inclusion threshold ------
       0.36   10.8   3.3        6.7    6.8   0.5    2.5  2  DUF1471          Protein of unknown function (DUF1471)


Domain annotation for each model (and alignments):
>> dCMP_cyt_deam_1  Cytidine and deoxycytidylate deaminase zinc-binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.7   0.0     1e-15   4.6e-12      16      98 ..     304     391 ..     293     394 .. 0.83

  Alignments for each domain:
  == domain 1  score: 45.7 bits;  conditional E-value: 1e-15
                      HHHH.TTTSCSEEEEEEETTEEEEEEESBHHCCTGTTB-HHHHHHHHHHHHTSSCETTEEEEE....EE--BHHHHHHHHHHT-SEEE CS
  dCMP_cyt_deam_1  16 keaq.kcsnfkVGavivkngeiistgyngepaggsktiHAEvnAilkaaknggsklegatlyv....tlePCsmCakaiiqsgikkvv 98 
                      ++   ++s+f+VGa++++ +  ++ g+n e+a+++  ++AE++A  +a+ +g+ +++   +++      +PC+mC++++ ++ + ++ 
       EEA22295.1 304 DKDGgPYSKFRVGACLITATGEYIFGANIENASYPVGVCAERVAFGNALMQGHKSFKAIAVATdikpGASPCGMCRQFMREFTTPTFP 391
                      4444599***********999****************************99877895555555888889***********99877665 PP

>> dCMP_cyt_deam_2  Cytidine and deoxycytidylate deaminase zinc-binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.1      0.87   3.9e+03      45      71 ..      12      36 ..       3      44 .. 0.65
   2 !   17.5   0.2   8.3e-07    0.0037      59     115 ..     307     364 ..     202     369 .. 0.86
   3 !    5.9   0.1    0.0031        14       3      14 ..     408     419 ..     406     420 .] 0.89

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.87
                     -HHHHHHHHHHTT-B-TTT---EEEEE CS
  dCMP_cyt_deam_2 45 delkeaAlaaanasyapyskcpsGvaL 71
                     +++ ++A++a  ++y  y ++ps + L
       EEA22295.1 12 QTISQKAIDAKAKAY--YLQAPSMLPL 36
                     457788888877777..6666665555 PP

  == domain 2  score: 17.5 bits;  conditional E-value: 8.3e-07
                      B-TTT---EEEEEEETTS-EEEEE-B--TTSTT-B-HHHHHHHHHHH.TT--GGGEEE CS
  dCMP_cyt_deam_2  59 yapyskcpsGvaLvtkdgkvyaGsyiEsaAfNpsLpPlqaAlvalvl.ggkefeeier 115
                        pysk   G  L t+ g+ + G  iE+a +     + ++A  ++++ g k+f+ i  
       EEA22295.1 307 GGPYSKFRVGACLITATGEYIFGANIENASYPVGVCAERVAFGNALMqGHKSFKAIAV 364
                      56*********************************************55566777765 PP

  == domain 3  score: 5.9 bits;  conditional E-value: 0.0031
                      HHSTT--SGGGG CS
  dCMP_cyt_deam_2   3 slLPhsFgPkdL 14 
                      +lLP+sFgP+dL
       EEA22295.1 408 ELLPDSFGPDDL 419
                      79*********9 PP

>> LmjF365940-deam  A distinct subfamily of CDD/CDA-like deaminases
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.5   0.4   0.00032       1.4     102     102 ..     364     364 ..     316     406 .. 0.52

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00032
  LmjF365940-deam 102 v 102
                      v
       EEA22295.1 364 V 364
                      3 PP

>> DUF1471  Protein of unknown function (DUF1471)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.5    0.0015       6.7      21      38 ..      12      29 ..       2      33 .. 0.84
   2 ?    4.1   0.1      0.01        46       7      29 ..      63      85 ..      59      86 .. 0.88

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0015
                HHHHHHHHHCT-SEEEEC CS
     DUF1471 21 dalskkAdekGAkyYrIt 38
                + +s+kA  + Ak+Y+ +
  EEA22295.1 12 QTISQKAIDAKAKAYYLQ 29
                579************976 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.01
                EEECSS-SSHHHHHHHHHHHHHH CS
     DUF1471  7 isvsgvfgspsdledalskkAde 29
                i  +g+   p+d+e++ s kAde
  EEA22295.1 63 IVSRGQTVEPMDVEEDQSDKADE 85
                667789999*************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (420 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       829  (0.0462379); expected 358.6 (0.02)
Passed bias filter:                      482  (0.0268838); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 2778.31
//
Query:       EEA22296.1  [L=668]
Description: hypothetical protein PMAA_060740 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-05   25.2   6.8     0.0015   18.9   1.9    2.3  2  HET       Heterokaryon incompatibility protein (HET)


Domain annotation for each model (and alignments):
>> HET  Heterokaryon incompatibility protein (HET)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   1.9   8.5e-08    0.0015       1      80 [.     190     264 ..     190     267 .. 0.80
   2 !    8.7   0.2   0.00012       2.1     123     146 .]     276     299 ..     271     299 .. 0.83

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 8.5e-08
         HET   1 YeaLSYvW..gdskekeeievngklleltenledalqvlrk.lgerylWiDaiCInQdddkekskqvqlmadIYsnAelviva 80 
                 + a+S+vW  g + ++e+           + l+ +l+++ +  +++++W D   I  d ++ ++  +++m+++Ys+A++++v+
  EEA22296.1 190 FMAISHVWshGWQGSTEDG-------ICSRVLDMLLEIAATkFNVQWIWLDVAMISSD-KSIRAMAINSMDTVYSTAKATLVV 264
                 6799999944333333333.......3578889999998776899******9999988.99******************9985 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.00012
         HET 123 ekeeraieellespwfkRvWvlQE 146
                 e++ ++  +++ s w++R+W++QE
  EEA22296.1 276 EDDMQTALTIIASDWMTRLWTMQE 299
                 566677778999***********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (668 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       515  (0.0287244); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.66u 0.30s 00:00:00.96 Elapsed: 00:00:00.47
# Mc/sec: 4229.42
//
Query:       EEA22297.1  [L=1504]
Description: vacuolar protein sorting protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.3e-284  943.8   6.5     2e-145  485.0   3.0    2.1  2  Sortilin-Vps10  Sortilin, neurotensin receptor 3,
    7.1e-95  316.1  14.5    3.6e-49  167.4   4.1    2.4  2  Sortilin_C      Sortilin, neurotensin receptor 3, C-terminal
    1.3e-12   45.7  29.5       0.48   10.6   0.2   10.2  9  BNR             BNR/Asp-box repeat
    1.6e-06   27.6   2.4        0.6    9.3   0.0    4.6  4  PSII_BNR        Photosynthesis system II assembly factor YCF4
  ------ inclusion threshold ------
       0.11   11.6   0.5       0.66    9.1   0.1    2.5  4  DUF2167         Protein of unknown function (DUF2167)
       0.61   10.6   6.8        9.9    6.7   0.3    2.7  2  preSET_CXC      CXC domain


Domain annotation for each model (and alignments):
>> Sortilin-Vps10  Sortilin, neurotensin receptor 3,
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  460.4   0.1    2e-141  5.9e-138       2     443 ..      68     517 ..      67     520 .. 0.95
   2 !  485.0   3.0  6.8e-149    2e-145       2     445 ..     737    1184 ..     736    1185 .. 0.95

  Alignments for each domain:
  == domain 1  score: 460.4 bits;  conditional E-value: 2e-141
                     EEEEESSTTSS-EE-GGGGTTEEBE....-EEE-STTS--EEEEEES-EEEEESSTTSSEEEEE-SS-BS....S--EEESSETTEEEEE..... CS
  Sortilin-Vps10   2 evyiSeDeGktwkkvkeklkgeaiq....eivvhpfdkkkaylltdskklyvttDrGktwkkfklpfkpsl.saeplsfhakdkdwlialgekke 91 
                     evy+S D G +w+ + + + +e ++     i +h++d+kkay+l++++ ++vttD+G+tw++f++p+ ps+   e+l+fh +d++++i++ge+++
      EEA22297.1  68 EVYRSFDGGLEWHVIGKGEGEEGLTndavVILPHKYDNKKAYILGRHGAHWVTTDQGRTWRRFEVPAAPSMlLYERLRFHGEDSRKVIFMGERCS 162
                     89*************9877766666888899**************************************************************** PP

                     ..BTTS-EEEESSTTSSEEEEESSEEEEEE-S................TT-EEEEE-SSS-TTTTTTSEEEEEESSTTSS-EEEE.......... CS
  Sortilin-Vps10  92 skdckkkayystdggkswkklqesvkkcewakss...........kkkeekilceekeeeseseekkklrlvssddffkskkelk.........s 166
                        c ++a+y+ d+++++  l++ +++c wa+ +           k+ ++++lc ++  ++       +rlv+sd+ffk++++           +
      EEA22297.1 163 LVACLETAFYTLDDFETVAPLRDTARGCFWAVGTpafaestteyaKEIGDRVLCIVHGLKN--PFAAAYRLVYSDSFFKDNEDGIeanlnagrpV 255
                     ******************************666666777778999999*********9887..89**************99766668899****9 PP

                     EEEEEEEEETTEEEEEEE-TTSS-EEEEEESSTSS-EE-SSS.-B-TT--EEEEEEESSEEEEEEE-SSSTS.EEEEEEE-TTSSCEEEEEEEEB CS
  Sortilin-Vps10 167 egvvsfavvkeflvvavkseetselalyvSldgkkfaeaefpskkleekaytvlessehsiflavttssdke.lgsllkSnsnGtsfvlslenvn 260
                      g+++ a++ ++++va+ks++t+ela++v++d+ ++++aef ++k+ee aytvl  +++si+++v++++++e +g l++SnsnGt+f++++e++n
      EEA22297.1 256 AGIINAAARTKYIMVAAKSQGTDELAMFVTDDAITWHRAEFGNHKIEEGAYTVLGGTNYSIQVDVKNTDRSEsMGVLFTSNSNGTYFTRNIEHTN 350
                     *****************************************************************98887755********************** PP

                     -TTTS-B--EEETTSTTEEEEEEE-T..........TS-EEEEEESSTTS-EEEEE--TTSSSTTT-SSSSB-EEEEE-HHHHHTT-S-SS--B- CS
  Sortilin-Vps10 261 rneegyvdfekvegleGvilanvvknaeev..kkgakkklktkItfddGrtWellkppdkdkygcsskklekcsLhLhsyteelerknvgrkvfS 353
                     rn egyvdfe + g++G++l+nvv+n+eev  k +a+kk+ +kI+fddGrt+++lk++dkd             Lh+hs+t+    +n+gr vfS
      EEA22297.1 351 RNMEGYVDFEDIIGVQGIVLVNVVDNWEEVekKFDADKKVISKISFDDGRTFQPLKANDKD-------------LHVHSVTD---FQNIGR-VFS 428
                     ******************************8777899*********************987.............******99...789988.*** PP

                     -TTSTT-EEEEEEEESSHHSS..S-EEEEESSSSSS-EEEESS-EEEEEEGGGTEEEEEE-SSS-B-EEEEESSTTSSEEEEE--SS-BEE CS
  Sortilin-Vps10 354 spsApGlimgvGnvGkslksy.eeadtfiSrDaGltWkevlkgahkyefGDqGsiivavkdeeketkelsYSlDeGktWeeykfsdekirv 443
                     sp ApG+++gvGn+G++lksy +++++++S+DaG+tW+ +l+++hkye+G++G +iva+kd++++t ++++S+++Gk+W+++++  +ki +
      EEA22297.1 429 SP-APGIVLGVGNTGSHLKSYtKDGNLYVSDDAGVTWRLALEKPHKYEIGNKGAVIVAIKDDGDPTGKIQFSINHGKDWDTAELD-HKIIP 517
                     **.******************999************************************************************9.77765 PP

  == domain 2  score: 485.0 bits;  conditional E-value: 6.8e-149
                      EEEEESSTTSS-EE-GGGGTTEEBE-EEE-STTS--EEEEEES-EEEEESSTTSSEEEEE-SS-BS....S--EEESSETTEEEEE....... CS
  Sortilin-Vps10    2 evyiSeDeGktwkkvkeklkgeaiqeivvhpfdkkkaylltdskklyvttDrGktwkkfklpfkpsl.saeplsfhakdkdwlialgek.kes 92  
                      ++y+++++Gktw++  +  + +  +eiv +p+ +++a++lt++kk ++t +r++t+++f++p++++   +++l fh+  kdw+i++g + +++
      EEA22297.1  737 KLYVTHNHGKTWTHELT--DVK-FEEIVRNPYLNDRAFFLTNGKKQFYTINRAETFESFTAPAEKNPdPGMTLGFHEIYKDWMIWTGPSdCSH 826 
                      79***********9864..333.34699***************************************99******************999*** PP

                      .BTTS-EEEESSTTSSEEEEESSEEEEEE-S........TT-EEEEE-SSS-TTTTTTSEEEEEESSTTSS-EEEE.EEEEEEEEETTEEEEE CS
  Sortilin-Vps10   93 kdckkkayystdggkswkklqesvkkcewakss...kkkeekilceekeeeseseekkklrlvssddffkskkelksegvvsfavvkeflvva 182 
                       +c k  y+++ +g+ w+ l + v +ce+  ++   +++++ i+c+++e e+    ++++ lv+s+dff+++k++   +++ fa  +ef+++a
      EEA22297.1  827 GNCPKDSYFTKHRGDGWEILLRAVINCEFMAQEsrgEESNNLIFCNQHEAEE---VDGQRMLVTSNDFFDTSKTPL-PRIIAFAKASEFIIIA 915 
                      *****************************65555889***********9987...89*******************.**************** PP

                      EE-.TTSS-EEEEEESSTSS-EE-SSS...-B-TT--EEEEEEESSEEEEEEE-SSST..SEEEEEEE-TTSSCEEEEEEEEB-TTTS-B--E CS
  Sortilin-Vps10  183 vks.eetselalyvSldgkkfaeaefp..skkleekaytvlessehsiflavttssdk..elgsllkSnsnGtsfvlslenvnrneegyvdfe 270 
                      + + e+++ ++  vS+dg +fa+ae+    +++ e  yt l+s++hs+f++vt ++++  ++g l+kSnsnGts+vlsl++vnr+++gyvdfe
      EEA22297.1  916 KPDpEKEHAMKFDVSVDGVTFADAEYSvnLEVSMELGYTLLQSTTHSVFMHVTLNDQRdhQYGLLIKSNSNGTSYVLSLSDVNRSNDGYVDFE 1008
                      ***777889******************8667779999***************988765537******************************** PP

                      EETTSTTEEEEEEE-T........TS-EEEEEESSTTS-EEEEE--TTS......SSTTT-SSSSB-EEEEE-HHHHHTT-S-SS--B--TTS CS
  Sortilin-Vps10  271 kvegleGvilanvvknaeevkkgakkklktkItfddGrtWellkppdkd......kygcsskklekcsLhLhsyteelerknvgrkvfSspsA 357 
                      k++gleGv++anvv+n+++v+kg++kkl+t+It++dG++W+l++pp kd      ++g++ k ++kc+LhLh+yte   r++ +r++f s+sA
      EEA22297.1 1009 KLQGLEGVVIANVVSNTKDVEKGSEKKLRTMITHNDGAQWTLIPPPVKDsegkgyNCGSDGKPTDKCALHLHGYTE---RRD-SRNTFASASA 1097
                      *************************************************9999888889*****************...566.588******* PP

                      TT-EEEEEEEESSHHSS.S-EEEEESSSSSS-EEEESS-EEEEEEGGGTEEEEEE-SSS-B-EEEEESSTTSSEEEEE--SS-BEEEE CS
  Sortilin-Vps10  358 pGlimgvGnvGkslksyeeadtfiSrDaGltWkevlkgahkyefGDqGsiivavkdeeketkelsYSlDeGktWeeykfsdekirvld 445 
                      +Gl +gvGnvG+sl s+++a+tf+SrD+G++Wkev+kg+h++e+GDqGs++v+v + + +t+e+ +S+DeG+tWe y+fs+++++vld
      EEA22297.1 1098 IGLSFGVGNVGESLVSKADASTFFSRDGGISWKEVKKGSHFWEYGDQGSVLVLVAEGK-PTREVFFSTDEGDTWEVYQFSEKEVTVLD 1184
                      *********************************************************6.*************************9986 PP

>> Sortilin_C  Sortilin, neurotensin receptor 3, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  167.4   4.1   1.2e-52   3.6e-49       1     170 []     522     684 ..     522     684 .. 0.89
   2 !  154.1   2.7   1.4e-48   4.3e-45       1     170 []    1187    1355 ..    1187    1355 .. 0.89

  Alignments for each domain:
  == domain 1  score: 167.4 bits;  conditional E-value: 1.2e-52
  Sortilin_C   1 tepdstslkflllgksssedkekvvvislDFsklferkCkeeeDyekwsareeek.kekCllGhkqkyrrrkkdakCfvge.kfkdpkv.eenCeCtee 96 
                 t+pdstslkfll+g s+++  +k+ ++++DF++l+er+Ck e+D+e+w ar +ek +++Cl+Ghkq yrrrk+da+Cf++e  fk p+   + C+Ct e
  EEA22297.1 522 TTPDSTSLKFLLVGFSEES--RKWSIFAIDFEGLHERECK-ESDFEEWPARLDEKgEPDCLMGHKQYYRRRKSDADCFITEtMFKTPTPeFKACKCTAE 617
                 89************99988..458888************7.77*********9999***********************99345668888999****** PP

  Sortilin_C  97 DfeCdynfereesegkCvlaeklevpdeeekevCkkkkkkeksylkssgyrkipgntC..eggkekdkdekvekpC 170
                 DfeCdynf+r+e+++kCv+a +l++p+++    Ck  +++++ ++++sg+r+ipgn C  +gg  ++ d+++++pC
  EEA22297.1 618 DFECDYNFVRSEDRTKCVPATPLKAPEGA----CK--SEDDT-FKGPSGWRLIPGNACirDGG--EELDKEIDRPC 684
                 *************99************98....*4..45455.9**************76566..55677799998 PP

  == domain 2  score: 154.1 bits;  conditional E-value: 1.4e-48
  Sortilin_C    1 tepdstslkflllgksssedkekvvvislDFsklferkCke......eeDyekwsareeekkekCllGhkqkyrrrkkdakCfvgekfkd.pkveen 90  
                  t+p++ts++fl+++++  +  +k v+i+lDFs+l++r+C+       +eDy+ w++++  ++ +Cl+Gh ++y+r++++++C+++ +  + +++++n
  EEA22297.1 1187 TVPSDTSKNFLIWAREAGS--DKLVTINLDFSGLRDRTCHLdedtgeSEDYYIWEPKHPLQEGNCLFGHVEQYHRKNPKSHCWNDWSEAHvHSISHN 1281
                  79************99887..56****************8899888766*********66699**********************976663666*** PP

  Sortilin_C   91 CeCteeDfeCdynfereesegkCvlaeklevpdeeekevCkkkkkkeksylkssgyrkipgntCeggkekdkdekvekpC 170 
                  C+Ct +D+eCdyn+er+++ g+C l+++l+ p+    e Ck+ +++   y +++gyr+ip +tC+gg  k+ d+ +++pC
  EEA22297.1 1282 CSCTFQDYECDYNYERQTD-GSCALVPGLPKPNA--IEYCKE-NPDAVEYWEPTGYRRIPITTCTGG--KNLDQWISHPC 1355
                  ****************876.9************5..59**65.444446999***************..55566799999 PP

>> BNR  BNR/Asp-box repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.1     0.021        63       1      11 [.      70      80 ..      70      81 .. 0.92
   2 !    9.2   0.5   0.00046       1.4       1      11 [.     118     128 ..     118     129 .. 0.91
   3 ?    4.7   0.0     0.014        42       2      11 ..     394     403 ..     393     404 .. 0.89
   4 !    9.5   0.0   0.00037       1.1       1      11 [.     455     465 ..     455     466 .. 0.92
   5 ?    2.8   0.4      0.06   1.8e+02       1      11 [.     497     507 ..     497     508 .. 0.89
   6 !    9.7   0.3   0.00032      0.96       1      11 [.     739     749 ..     739     750 .. 0.92
   7 ?   -0.8   0.0      0.92   2.7e+03       2      11 ..    1040    1049 ..    1039    1050 .. 0.87
   8 !   10.6   0.2   0.00016      0.48       1      11 [.    1120    1130 ..    1120    1131 .. 0.91
   9 !    8.3   0.2   0.00095       2.8       1      11 [.    1161    1171 ..    1161    1172 .. 0.93

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.021
                EEESSTTSS-E CS
         BNR  1 yyStDgGktWs 11
                y S+DgG  W+
  EEA22297.1 70 YRSFDGGLEWH 80
                89******998 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00046
                 EEESSTTSS-E CS
         BNR   1 yyStDgGktWs 11 
                 +++tD+G+tW 
  EEA22297.1 118 WVTTDQGRTWR 128
                 79********7 PP

  == domain 3  score: 4.7 bits;  conditional E-value: 0.014
                 EESSTTSS-E CS
         BNR   2 yStDgGktWs 11 
                 +S+D G+t++
  EEA22297.1 394 ISFDDGRTFQ 403
                 8********8 PP

  == domain 4  score: 9.5 bits;  conditional E-value: 0.00037
                 EEESSTTSS-E CS
         BNR   1 yyStDgGktWs 11 
                 y+S+D G tW 
  EEA22297.1 455 YVSDDAGVTWR 465
                 89********7 PP

  == domain 5  score: 2.8 bits;  conditional E-value: 0.06
                 EEESSTTSS-E CS
         BNR   1 yyStDgGktWs 11 
                 ++S ++Gk W 
  EEA22297.1 497 QFSINHGKDWD 507
                 69********7 PP

  == domain 6  score: 9.7 bits;  conditional E-value: 0.00032
                 EEESSTTSS-E CS
         BNR   1 yyStDgGktWs 11 
                 y+++++GktW+
  EEA22297.1 739 YVTHNHGKTWT 749
                 89********8 PP

  == domain 7  score: -0.8 bits;  conditional E-value: 0.92
                  EESSTTSS-E CS
         BNR    2 yStDgGktWs 11  
                  ++++ G  W+
  EEA22297.1 1040 ITHNDGAQWT 1049
                  89*****998 PP

  == domain 8  score: 10.6 bits;  conditional E-value: 0.00016
                  EEESSTTSS-E CS
         BNR    1 yyStDgGktWs 11  
                  ++S+DgG++W+
  EEA22297.1 1120 FFSRDGGISWK 1130
                  79********8 PP

  == domain 9  score: 8.3 bits;  conditional E-value: 0.00095
                  EEESSTTSS-E CS
         BNR    1 yyStDgGktWs 11  
                  ++StD G tW+
  EEA22297.1 1161 FFSTDEGDTWE 1171
                  79********7 PP

>> PSII_BNR  Photosynthesis system II assembly factor YCF48
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.0    0.0002       0.6      32      99 ..      61     132 ..      43     163 .. 0.74
   2 !    5.6   0.0    0.0028       8.3      48     145 ..     375     472 ..     354     545 .. 0.81
   3 !    8.0   0.0   0.00052       1.6     116     207 ..     727     820 ..     721     890 .. 0.72
   4 ?   -0.1   0.1      0.15   4.4e+02      79     101 ..    1154    1177 ..    1111    1181 .. 0.54

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.0002
                 EEEETTTEEEEESSTTSS-EE-----S--.....--EEEEEEEETTEEEEEEETTEEEEESSTTSS-EE--- CS
    PSII_BNR  32 flvGtkatlletlDGGktWeersldleee....vnyrlesvsfkgdegwivGkPslllhttdgGksWerikL 99 
                 fl  ++  ++ ++DGG +W+     + ee      + +   +++++ ++i+G+      ttd+G++W r ++
  EEA22297.1  61 FLSAATGEVYRSFDGGLEWHVIGKGEGEEgltnDAVVILPHKYDNKKAYILGRHGAHWVTTDQGRTWRRFEV 132
                 666777788889999999987764433331100133444457888899999999999999999999988764 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0028
                 SS-EE-----S--.--EEEEEEEETTEEEE...EEETTEEEEESSTTSS-EE----TT-SS-EEEEEEEETTEEEEEETT--EEEESSTTSSEEEEE-S CS
    PSII_BNR  48 ktWeersldleeevnyrlesvsfkgdegwi...vGkPslllhttdgGksWerikLsekLPGePllitalgkkkaelvtdvgaiYrtedagknWkaqvee 143
                 ++Wee + +++++ +  ++++sf++   +    + +  l +h+  + ++  r+  s   PG  l + ++g++     t+ g +Y ++dag +W+ + e+
  EEA22297.1 375 DNWEEVEKKFDAD-KKVISKISFDDGRTFQplkANDKDLHVHSVTDFQNIGRVFSS-PAPGIVLGVGNTGSHL-KSYTKDGNLYVSDDAGVTWRLALEK 470
                 5788888888777.667899999999888522255667999999999999999655.5688888888877664.557999*************988876 PP

                 -- CS
    PSII_BNR 144 av 145
                 + 
  EEA22297.1 471 PH 472
                 65 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.00052
                 TEEEEEETT--EEEESSTTSSEEEEE-S----EEEEEE-...TTS-EEEEETTSSEEEEE-TT-.SS-EEEE--SSS-EEEEEE-TTS-EEEEETT CS
    PSII_BNR 116 kkaelvtdvgaiYrtedagknWkaqveeavGsirniers...edGeYvavssrGnfystwepgq.daWephnressrrlqnmGfepdgelWllarG 207
                 ++  + t++g +Y t++ gk+W+ + ++    +++i r+   +d ++     + +fy++ +++  +++++   +++    ++Gf++  + W++  G
  EEA22297.1 727 ETIVMLTSNGKLYVTHNHGKTWTHELTDVK--FEEIVRNpylNDRAFFLTNGKKQFYTINRAETfESFTAPAEKNPDPGMTLGFHEIYKDWMIWTG 820
                 567799*****************9998864..4444444222456666666777777766554323334334444444556677777777776666 PP

  == domain 4  score: -0.1 bits;  conditional E-value: 0.15
                  EETTE.EEEESSTTSS-EE----T CS
    PSII_BNR   79 GkPsl.llhttdgGksWerikLse 101 
                  GkP+  ++ +td+G++We  ++se
  EEA22297.1 1154 GKPTReVFFSTDEGDTWEVYQFSE 1177
                  566532566777777777666665 PP

>> DUF2167  Protein of unknown function (DUF2167)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.1   0.00022      0.66     128     191 ..     343     405 ..     332     414 .. 0.81
   2 ?   -2.2   0.0      0.61   1.8e+03      21      73 ..     952    1007 ..     942    1035 .. 0.63
   3 ?   -3.1   0.0       1.2   3.6e+03     150     185 ..    1012    1045 ..     993    1048 .. 0.74
   4 ?   -2.9   0.0      0.99   2.9e+03     116     135 ..    1189    1207 ..    1178    1215 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00022
     DUF2167 128 akelksedaeaektlNYnvrvLGReGvlslnlvasldqleevkkelekvlskvefneGkrYadf 191
                  +++++ +++ e  + ++  ++G +G++ +n+v + +++e+  ++ +kv+sk++f++G++++  
  EEA22297.1 343 TRNIEHTNRNMEGYVDFE-DIIGVQGIVLVNVVDNWEEVEKKFDADKKVISKISFDDGRTFQPL 405
                 555666666666666665.578*************************************98765 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.61
     DUF2167   21 gfaflnaedakkvleelwgnppsekelglvlpkdese.swav...vveyeesGyvkd 73  
                  g++ l+++  + +++ +  n + ++++gl+++++++  s+++    v+ +++Gyv+ 
  EEA22297.1  952 GYTLLQSTTHSVFMHVT-LNDQRDHQYGLLIKSNSNGtSYVLslsDVNRSNDGYVDF 1007
                  45555544444444444.566667888888887776644443111466777888865 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 1.2
     DUF2167  150 GReGvlslnlvasldqleevkkelekvlskvefneG 185 
                  G eGv+ +n+v++++++e+ ++  +k+ ++++ n+G
  EEA22297.1 1012 GLEGVVIANVVSNTKDVEKGSE--KKLRTMITHNDG 1045
                  6789999999999999886543..344455555555 PP

  == domain 4  score: -2.9 bits;  conditional E-value: 0.99
     DUF2167  116 PtYdaatkklvWakelksed 135 
                  P+ d++++ l+Wa+e+ s++
  EEA22297.1 1189 PS-DTSKNFLIWAREAGSDK 1207
                  54.899999*****998775 PP

>> preSET_CXC  CXC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   1.5    0.0066        20      11      23 ..     610     622 ..     606     625 .. 0.91
   2 ?    6.7   0.3    0.0033       9.9      11      23 ..    1280    1292 ..    1275    1295 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0066
  preSET_CXC  11 keClCvranRECd 23 
                 k+C+C +++ ECd
  EEA22297.1 610 KACKCTAEDFECD 622
                 79**********9 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0033
  preSET_CXC   11 keClCvranRECd 23  
                   +C C +++ ECd
  EEA22297.1 1280 HNCSCTFQDYECD 1292
                  58**********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1504 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       518  (0.0288917); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.88u 0.32s 00:00:01.20 Elapsed: 00:00:00.53
# Mc/sec: 8566.75
//
Query:       EEA22298.1  [L=538]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (538 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       848  (0.0472977); expected 358.6 (0.02)
Passed bias filter:                      441  (0.024597); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.59u 0.32s 00:00:00.90 Elapsed: 00:00:00.48
# Mc/sec: 3359.46
//
Query:       EEA22299.1  [L=917]
Description: Exocyst complex component Sec10, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   3.3e-229  763.0   0.0   3.9e-229  762.7   0.0    1.0  1  Sec10         Exocyst complex component Sec10
  ------ inclusion threshold ------
      0.014   14.9   0.0      0.054   13.0   0.0    1.9  2  LpxC          UDP-3-O-acyl N-acetylglycosamine deacetylase
      0.083   12.6   1.3        0.1   12.3   0.1    1.7  2  GCD14         tRNA methyltransferase complex GCD14 subunit
      0.097   12.5   0.6        2.9    7.7   0.0    2.9  2  BP28CT        BP28CT (NUC211) domain
       0.17   11.9   7.4          6    6.9   0.2    3.8  4  Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C


Domain annotation for each model (and alignments):
>> Sec10  Exocyst complex component Sec10
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  762.7   0.0  1.1e-232  3.9e-229       3     709 ..     128     912 ..     126     914 .. 0.98

  Alignments for each domain:
  == domain 1  score: 762.7 bits;  conditional E-value: 1.1e-232
       Sec10   3 evvdsfnqLddkise................vgqtavklgeqLesadkqrqraseaaeLiefykeflssgetsklellfkkskdpekklkaAqiarkLl 85 
                  +++sf++Ld++++                  ++ av++g++Le++++qr+ra++a++Lie+++e++++g+++kle l + s++ e+kl+aA+ia++Ll
  EEA22299.1 128 HAIESFQKLDTSLNGaplisssatssngvpeSSNVAVEVGKKLEELERQRRRALDAHFLIECWDEVSNRGDVTKLETL-RMSGNSEGKLRAAHIAKQLL 225
                 6899**************************************************************************.******************** PP

       Sec10  86 aiskeld...............................elekaentrekiekyaerlEkelLkeFdkayrkedfermkeiAkvLqefnggasvvqlfvn 153
                 +is++ld                               +    + tre iek++e+lEk+lLk+Fd++yrk++f++mke+A+vL +fnggasv++lfvn
  EEA22299.1 226 RISQRLDpkswndtsngnghyanseglmspglngngngNHFPKKDTREIIEKFSETLEKDLLKQFDDFYRKANFDGMKECASVLRDFNGGASVIALFVN 324
                 **********************************99875555688****************************************************** PP

       Sec10 154 qhdffidkdkl..deangiesseiwekladpdeapskveeslqalfseiretvkeeaeiikrVFpnpekVmqtFlqrvfaqviqqrlealLdkassisq 250
                 qh+ffid+++l  +e  g  + e+wekladpd++p+ ve+slq+l+++++++v+ e++ii+r+Fp++ +V++ Flqrvf+q+iqqrle++Ldka+s+s+
  EEA22299.1 325 QHQFFIDRSQLvtEEIGG--DAETWEKLADPDADPPGVEPSLQSLVDDVKVVVQDESTIIRRAFPYYDEVLSRFLQRVFQQSIQQRLEMVLDKANSVSS 421
                 ***********9888888..459**************************************************************************** PP

       Sec10 251 layLraLhslysstlkLvkdLkeylsteeidgssa.lsalLdqsveelFvpylegdsYlerEkksLeelyaellskFttlheqsasakslknkvkkkla 348
                 la+Lr+L+s++s++++Lv+dLk+++ te +d  s+ ++  Ldq++e+lFvpy++g+sY+erEk++Leely++ll+kFt +h++           kk+++
  EEA22299.1 422 LAFLRSLQSSRSYLNSLVDDLKAHGLTEAPDPISSqTAIVLDQQLEDLFVPYFVGSSYIEREKRNLEELYTSLLFKFTAFHAR----------RKKTAT 510
                 ************************9999*******9999*******************************************9..........89999* PP

       Sec10 349 tsfkasls..asklaassktkqinraasstlskskkr.....aelketaatsakaaknedeleeedsllslevaesllkwaaeslgRaveLsspsevpk 440
                 t+f+asl   +s+l as+k+++  r++ss+ ++++++     a+l+++ + s+  +  e e++eed+lls+ +a+++lkw ae +gR +eLs +se+pk
  EEA22299.1 511 TTFMASLAksGSELLASAKESYLYRLESSDSTPTQRQmllrvAGLRDSGDVSG--KPAEPEFTEEDGLLSVAYAKRMLKWLAEGVGRGLELSVSSETPK 607
                 *******999999*************************************996..899***************************************** PP

       Sec10 441 aveallelLlsalgkeYvetaLdaalaaltaqeiaektevpdlsflevvrsvdliisllqvyiktillpllsdspdirremvkeknsflsrlEekvnag 539
                 +v++ll+lLls + + Y+e +L+aal+a+ aqe ++kte pd+ +l ++r++ ++++l+  +i+t+l+pl+ ++++ rr+m k++n ++sr+E+k+na+
  EEA22299.1 608 DVSSLLNLLLSTMAEGYIEIGLEAALDAALAQE-NTKTE-PDFTYLHTLRTAISVTHLMLTCINTVLIPLAANNVTTRRDMEKKTNAVVSRIEDKINAI 704
                 *********************************.77888.*********************************************************** PP

       Sec10 540 lqktidvvvgeveyllskqkknDFrpknddla..merqpTeaCkeivefLssvhsalkesls..gsnlesflteiGlrlhklLleHlkkftvsseGGlm 634
                  q+tidv   +v++ll  qkknDFrpk+d+ +  +e+ +T++C++i++fL+++++++ +sl   gsn +++ te++l +++++l+H+++f+vs +GGlm
  EEA22299.1 705 EQRTIDVALTWVSKLLGGQKKNDFRPKEDNSTawLEMLQTPTCESICTFLTQLQNTILTSLPpsGSNIRTLFTELALGVRSQILDHFRRFQVSGSGGLM 803
                 *****************************9999*999************************999*********************************** PP

       Sec10 635 ltkDlneYqdavksf...kipelsekFelLrelgnlfiVqpevlkslvregal...............................akldrelireyiqrR 699
                 +tkD+++Y +++ks+   + +++++  ++L e+g+lf+V pe+l++ +r+ a                                 +l++++ir+y+ rR
  EEA22299.1 804 VTKDMTRYANLLKSWdleDEEQVKAAIDVLLEVGSLFVVGPEALREKLRGPATsagstgtstnngngngnggnrptaaavatdgFALSVQDIRAYVMRR 902
                 ***************7777789******************************9******************************999************* PP

       Sec10 700 eDykkekldn 709
                 +D +++++++
  EEA22299.1 903 ADTNTAAMQS 912
                 ******9987 PP

>> LpxC  UDP-3-O-acyl N-acetylglycosamine deacetylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   1.5e-05     0.054     164     263 ..      20     120 ..       5     128 .. 0.83
   2 ?   -1.6   0.0      0.43   1.5e+03     153     213 ..     398     464 ..     365     467 .. 0.55

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 1.5e-05
                 CEEEEETTCCHHHHHTTT--EEEEHHHHHHHHHTTSSTT-STTTSEEEE.SSSBSSTT--SSTTHHHHHHHHHHHHHHGGGSSEEEEEEEEES--HHHH CS
        LpxC 164 qslslelseesfakeiapARTFgflkevealrkaglakGgsldnavvid.eekvlneeglrfedEfvrHKiLDliGDLallgapllghvvaykagHaln 261
                 qs +l  +  sf+ e  + R + +++ +e l    +a   s  +a   + +++ +++++l  + E ++  + Dl+GDL +  + l ++v   +a Ha n
  EEA22299.1  20 QSRTLYPRGPSFTLEYFSGRDYIVKDFIESLSDTAIASRRSAGTAAATStANQPFDPKPLIRTFEHAQRSLNDLLGDLEIRENELSAAVRRAEAQHAQN 118
                 4444444555899999999*******************999977777762669********************************************99 PP

                 HH CS
        LpxC 262 nk 263
                  +
  EEA22299.1 119 LN 120
                 65 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.43
                 EEEESSTTCCCCEEEEETTCC......HHHHHTTT--EEEEHHHHHHHHHTTSSTT...-STTTSEEEES CS
        LpxC 153 eidfehpaigeqslslelsee......sfakeiapARTFgflkevealrkaglakG...gsldnavvide 213
                 +  f+++   +q+l++ l++       +f +++ ++R++   + v+ l+++gl +     s ++a+v+d+
  EEA22299.1 398 QRVFQQSI--QQRLEMVLDKAnsvsslAFLRSLQSSRSYL-NSLVDDLKAHGLTEApdpISSQTAIVLDQ 464
                 33342222..244444443333345559999999999984.56788888888877522235577777765 PP

>> GCD14  tRNA methyltransferase complex GCD14 subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.1   2.8e-05       0.1      45      79 ..       7      41 ..       2      59 .. 0.82
   2 ?   -3.6   0.1         2   7.2e+03      69      85 ..     496     513 ..     492     516 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 2.8e-05
       GCD14 45 vesGtGsgslshaiartvaPtGhlftfefheqrae 79
                + s   s slsh+ +rt+ P+G  ft+e+   r  
  EEA22299.1  7 ISSSSHSRSLSHQQSRTLYPRGPSFTLEYFSGRDY 41
                6788899**********************998853 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 2
       GCD14  69 ftf.efheqraekareef 85 
                 f f  fh++r ++a   f
  EEA22299.1 496 FKFtAFHARRKKTATTTF 513
                 555259********9988 PP

>> BP28CT  BP28CT (NUC211) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.1     0.059   2.1e+02      84     123 ..     494     533 ..     462     560 .. 0.72
   2 ?    7.7   0.0    0.0008       2.9      17      50 ..     680     719 ..     666     758 .. 0.82

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.059
                 HHHHHHHHHH--------TTHHHHHHHHHHHHH------- CS
      BP28CT  84 tfykllnklaekLkslftsYasyllenavelLkalnekse 123
                  ++k+++  a + k+  t +++ l ++  elL +++e+  
  EEA22299.1 494 LLFKFTAFHARRKKTATTTFMASLAKSGSELLASAKESYL 533
                 58999999999999999**********9999988865532 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0008
                 HHHHHHHT----......HHHHHHHHHHHHHHHHHHHHH- CS
      BP28CT  17 ldlRreqaskke......eeeidevEesvieafvalvlKL 50 
                    Rr  ++k++      e +i+++E+ +i++++++v KL
  EEA22299.1 680 VTTRRDMEKKTNavvsriEDKINAIEQRTIDVALTWVSKL 719
                 55677777777788999999*******************9 PP

>> Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.2    0.0017         6      37      88 ..      91     141 ..      77     152 .. 0.69
   2 ?    2.1   0.0     0.051   1.8e+02      36     118 ..     364     445 ..     358     463 .. 0.72
   3 ?    2.0   0.5     0.055     2e+02      41      90 ..     666     716 ..     649     721 .. 0.70
   4 ?    3.0   1.7     0.027        98      30     111 ..     691     779 ..     665     792 .. 0.66

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0017
  Baculo_PEP_C  37 atlldaietqLnalsedlksllaeldtrldtlltnLtdalnalqdtlrneLt 88 
                   + ll ++e + n+ls++++++ a+ +++l+tl  +L++a+ ++q +l++ L+
    EEA22299.1  91 NDLLGDLEIRENELSAAVRRAEAQHAQNLNTLGRKLSHAIESFQ-KLDTSLN 141
                   34444455555667777777777777788888888888888887.4555554 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.051
  Baculo_PEP_C  36 latlldaietqLnalsedlksllaeldtrldtlltnLtdalnalqdtlrneLtnlnsi..ltnLlssvtNinstLnnllqalnnl 118
                   l++l+d+++ ++++ s+ ++++ +  d+ l+ +l+++ +  +++q+ l+  L+  ns+  l+ L  s+    s Ln+l+ +l++ 
    EEA22299.1 364 LQSLVDDVKVVVQDESTIIRRAFPYYDEVLSRFLQRVFQ--QSIQQRLEMVLDKANSVssLAFL-RSLQSSRSYLNSLVDDLKAH 445
                   777888888888888888888888888888888887755..46777888888777763114444.47777788888888888765 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.055
  Baculo_PEP_C  41 daietqLnalsedlksllaeldtrldtlltnLtdalnalq.dtlrneLtnl 90 
                   + i+t+L  l+++      +++++ ++++++++d++na++  t++ +Lt +
    EEA22299.1 666 TCINTVLIPLAANNVTTRRDMEKKTNAVVSRIEDKINAIEqRTIDVALTWV 716
                   455555555555444456788889999999999999999867888888766 PP

  == domain 4  score: 3.0 bits;  conditional E-value: 0.027
  Baculo_PEP_C  30 vqilaqlatlldaietq.Lnalsedlksllaeldt.rldtlltnLtdalnalq....dtlrneLtnl.nsiltnLlssvtNinstLnnl 111
                     +++ ++  ++aie++ ++   + +++ll  +++ ++    +n t+ l  lq    +++ + Lt l n+ilt+L  s  Ni +  + l
    EEA22299.1 691 NAVVSRIEDKINAIEQRtIDVALTWVSKLLGGQKKnDFRPKEDNSTAWLEMLQtptcESICTFLTQLqNTILTSLPPSGSNIRTLFTEL 779
                   33446666666666554144444556666665554578888888888888888888888888888884467788888777777665555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (917 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       704  (0.039266); expected 358.6 (0.02)
Passed bias filter:                      544  (0.0303419); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.79u 0.33s 00:00:01.12 Elapsed: 00:00:00.50
# Mc/sec: 5532.59
//
Query:       EEA22300.1  [L=391]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (391 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       861  (0.0480228); expected 358.6 (0.02)
Passed bias filter:                      600  (0.0334653); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 2538.84
//
Query:       EEA22301.1  [L=279]
Description: hypothetical protein PMAA_060800 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (279 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       522  (0.0291148); expected 358.6 (0.02)
Passed bias filter:                      254  (0.014167); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1918.77
//
Query:       EEA22302.1  [L=821]
Description: repressor protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.8e-29  103.6   0.0      3e-29  102.9   0.0    1.3  1  DHquinase_I     Type I 3-dehydroquinase
    2.5e-17   63.4   0.0    4.8e-17   62.5   0.0    1.5  1  SKI             Shikimate kinase
    5.2e-13   49.0   0.0    1.4e-12   47.7   0.0    1.8  1  Shikimate_dh_N  Shikimate dehydrogenase substrate binding dom
    8.3e-09   35.6   0.1    2.5e-08   34.1   0.0    1.7  2  Shikimate_DH    Shikimate / quinate 5-dehydrogenase
    3.2e-06   26.8   1.5      6e-06   25.9   1.5    1.5  1  SDH_C           Shikimate 5'-dehydrogenase C-terminal domain
  ------ inclusion threshold ------
      0.021   15.4   0.0      0.057   14.0   0.0    1.7  1  F420_oxidored   NADP oxidoreductase coenzyme F420-dependent


Domain annotation for each model (and alignments):
>> DHquinase_I  Type I 3-dehydroquinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.9   0.0     1e-32     3e-29      12     227 ..     254     471 ..     241     473 .. 0.87

  Alignments for each domain:
  == domain 1  score: 102.9 bits;  conditional E-value: 1e-32
                  HHHHHHHHTTS-SEEEEEGGG-.TT.THHHHHHHHHHHHHHTTS-EEEE---GGGT-S.....S.SS-HHHHHHHHHHHHHCT-SEEEEEGG-.HHGH CS
  DHquinase_I  12 ilaelesgkekaDlvElRlDllketseaedvseeleelrstsdlpliftlrtkaeggrf....k.rkseeeylellrtaielgadyvDvElteapees 104
                   la+lesg    D++El++D+++ ++  ++v++ ++ lr++++lp+i++++  a g       +  k+ + y+++l+ +++lg++y+ + l   ++++
   EEA22302.1 254 DLAKLESG---GDAIELCIDMWN-PDAVSTVAKHVSVLRRIAKLPIIYSIDAGALGLDArisdPaVKNGDLYFQILEYGLRLGVEYLAIHLD-HDHTR 346
                  45666666...9**********5.5567***********************86666665566533678899********************4.34335 PP

                  HHHHHHHHHHTT-EEEEEEE.ESS----HH..HHHHHHHHHHHTT-SEEEEEE--SSHHHHHHHHHHHHHHHHH.T-SS-EEEEE-TTTTGHHHCHHH CS
  DHquinase_I 105 kkrlieekreggtkvIvSyh.dfegtpsae..elkallekmqalgaDivKiavmaksieDvlrllsltseakee.kdeaplIamamGelGkiSRilge 198
                   +++++++  g tk+I+++  d ++  s+e  ++ +++ ++++lg+++v+i+  a+++e+++ + ++  ++k+    + p+Ia+++G+ G+ S+++++
   EEA22302.1 347 LTQIVQSR--GMTKIIGHFTiDISSGISWEdeACLSIYIEAERLGCQLVRIVRLATTREENDSVRKFVDRVKALsGSHPPIIAFNIGPIGRSSQVFNN 442
                  55777777..99*******99*********999*****************************************9999******************** PP

                  HHTB-EEEEESS.S-..SSTT-EEHHHHHH CS
  DHquinase_I 199 vfGspvtfasle.eakasapGqltarelre 227
                  ++ ++v +++++ +a ++  +q+t +++ +
   EEA22302.1 443 TL-TSVAHPAISpSALRANDPQITSQDAIR 471
                  **.*******998999999*****998755 PP

>> SKI  Shikimate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.5   0.0   1.6e-20   4.8e-17       1     106 [.      38     147 ..      38     195 .. 0.88

  Alignments for each domain:
  == domain 1  score: 62.5 bits;  conditional E-value: 1.6e-20
                 TTSSHHHHHHHHHHHHTSEEEEHHHHHHHHHTS-HHHHHHHHHHHHHHHHHHHHHHHHCCCS..SEEEEE-TTG...GGSHHHHHHHHHHSEEEEEE-- CS
         SKI   1 mGaGKstvGkllAkklglefiDlDeliekrtgksiaeifeeegeegFrelEsevlkelleee..glViatGGGa...vlseenrellkekgiviyLdvs 94 
                 +G+GK ++G + A +l+++fi  D +++++tg + +e++ + g  +F++++ evlk +l+++  ++Vi +G G+   +++e  r++   +++v+yL ++
  EEA22302.1  38 RGSGKRSLGFIAAAALNRRFITEDYYFKEVTGLTRHEFLLKFGSHEFQRRDVEVLKMMLDNHrtHCVIECGLGSltrIIQEHLRQYAL-TNPVVYLLRD 135
                 7*********************************************************************999722245666777777.9********* PP

                 HHHHHHHHHHTT CS
         SKI  95 leellerlkadk 106
                 ++++++ l+ ++
  EEA22302.1 136 MDQIQRLLQLQD 147
                 *****9998665 PP

>> Shikimate_dh_N  Shikimate dehydrogenase substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.7   0.0   4.5e-16   1.4e-12       1      83 []     486     566 ..     486     566 .. 0.97

  Alignments for each domain:
  == domain 1  score: 47.7 bits;  conditional E-value: 4.5e-16
                     EEESS-TT-SHHHHHHHHHHHCTSSEEEEEEE-SCCTHHHHHHHHHHTTESEEEE-TTSCCHHHGGSSEE-HHHHHHT--SEE CS
  Shikimate_dh_N   1 viGnpikhSlSPaihnaafkalglngsyeafeveedelekaveelralglaGlnvTiPfKeaviplldelseeAkaigAvNti 83 
                     ++G+ +++S SPa+hnaa++++gl ++y+  + +  +l  + e  +++++ G +v  P+  +v   l   s++A+aigA+Nt+
      EEA22302.1 486 ILGASVAYSISPAMHNAAYASCGLSHVYRIPDAP--SLALLDEWCHDPHFGGSSVVQPWRVHVAGQLKYKSRHAEAIGAINTV 566
                     689******************************9..99988899999***********************************8 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       1.7   5.2e+03       4      51 ..      93     141 ..      90     147 .. 0.68
   2 !   34.1   0.0   8.4e-12   2.5e-08      16      59 ..     628     671 ..     620     690 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 1.7
                   HHHHS..TT-EEEEES-SHHHHHHHHHHHCCT-CE.EEEEESSHHHHHH CS
  Shikimate_DH   4 kkkleslkekkvlliGaGemaelvakhLlakgvkk.vvvaNRtlerake 51 
                   k+ l++++++ v+  G G + + + +hL +  +++ vv + R++++ ++
    EEA22302.1  93 KMMLDNHRTHCVIECGLGSLTRIIQEHLRQYALTNpVVYLLRDMDQIQR 141
                   5566677777777789999999999999887666513444566665555 PP

  == domain 2  score: 34.1 bits;  conditional E-value: 8.4e-12
                   EEES-SHHHHHHHHHHHCCT-CEEEEEESSHHHHHHHHHHHT.E CS
  Shikimate_DH  16 lliGaGemaelvakhLlakgvkkvvvaNRtlerakelaeelkge 59 
                   l+iGaG ma+ ++ ++l+ g++k++++NRtl+ra+e+a+++++ 
    EEA22302.1 628 LVIGAGGMARAAIYAMLQLGCRKIFILNRTLSRAEEVARHFNSW 671
                   8**************************************99654 PP

>> SDH_C  Shikimate 5'-dehydrogenase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.9   1.5     2e-09     6e-06       1      30 [.     767     796 ..     767     797 .. 0.93

  Alignments for each domain:
  == domain 1  score: 25.9 bits;  conditional E-value: 2e-09
                 HHHHHHHHHHHHHHHHHS----HHHHHHHH CS
       SDH_C   1 GLgMLveQgaeqFelWTGrepPvevMreal 30 
                 GL+   eQg++q+el+TGr++P+  M+  +
  EEA22302.1 767 GLEIVAEQGFAQWELMTGRKAPRRLMMTEV 796
                 899999********************9876 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   1.9e-05     0.057       4      53 ..     629     675 ..     627     688 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1.9e-05
                    EETTSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC-EEECE CS
  F420_oxidored   4 iiGaGnmgealasgllaagaqpheivvansrnpekaeelaeelgvkvtav 53 
                    +iGaG m++a +  +l+ g   ++i +  +r+ ++aee a++++  v ++
     EEA22302.1 629 VIGAGGMARAAIYAMLQLG--CRKIFIL-NRTLSRAEEVARHFNSWVASS 675
                    79*****************..8999955.**************9444332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (821 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       426  (0.0237604); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.66u 0.26s 00:00:00.92 Elapsed: 00:00:00.46
# Mc/sec: 5332.80
//
Query:       EEA22303.1  [L=878]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.1e-22   79.4   0.0    6.9e-22   77.7   0.0    1.8  1  Fungal_trans  Fungal specific transcription factor domain
    2.2e-07   30.9  14.1    4.1e-07   30.0  14.1    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.7   0.0   7.7e-26   6.9e-22       2     230 ..     224     450 ..     223     612 .. 0.68

  Alignments for each domain:
  == domain 1  score: 77.7 bits;  conditional E-value: 7.7e-26
  Fungal_trans   2 drffsnfhpqfpilhkpsflpkt.......ssenssksayaspllllailalGalfsesetkesnssltsesqefiafpl........raeilihed 83 
                   +++fs +hp+fpi+ k+++l+         ++++++++ + +++ l+ail+      +s  ++ ++        f+++pl         a++li  +
    EEA22303.1 224 ETYFSQTHPWFPIIPKHNILRASymyangaNQSGNTPTSSGDHAALWAILSYTTGQENSGLNTHDA--------FVHDPLaqsreyyhMARSLI--P 310
                   68********************99****99999999999999999999987544444443333322........33333333333333888888..8 PP

  Fungal_trans  84 fsspssslwilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsq 180
                    ++++ +l ++q+Llll l++ +++d++++++++g a r+a  + L++   +        ++ e   +r+ ++ ++F++D ++++ l r p l+ ++
    EEA22303.1 311 SEKERFDLGHVQALLLLTLVNVGFEDWTAAWLLSGQAARMAEAMELSKPLDS-R------RSDE-TRQRKAVYMGCFVIDSILSVRLSRSPCLRSND 399
                   8888888****************************************65555.3......4445.7999**********************888888 PP

  Fungal_trans 181 inlpLPcddddlwesddaseetlvetk.lsneeksrkiasfllaLkkilsk 230
                    ++  P d+d l+e ++   +   +    s +  +r + ++l++++++ s 
    EEA22303.1 400 SDTVGPLDEDGLEEWNSWVDVLPSRAAfESRNAPRRGPLLALSCFNRLYSL 450
                   888877777765554333222222222244555566666666666666665 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.0  14.1   4.5e-11   4.1e-07       1      39 [.      17      54 ..      17      55 .. 0.91

  Alignments for each domain:
  == domain 1  score: 30.0 bits;  conditional E-value: 4.5e-11
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfysesskr 39
                +aCd+Cr kK KCd+ +P+Cs C+  + +C+ y+   ++
  EEA22303.1 17 RACDRCRTKKDKCDGARPTCSACQATGQTCS-YDPNARK 54
                69*****************************.8876665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (878 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      253  (0.0141112); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.66u 0.31s 00:00:00.97 Elapsed: 00:00:00.47
# Mc/sec: 5657.92
//
Query:       EEA22304.1  [L=489]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.4e-23   81.5  18.7    5.4e-23   81.5  18.7    2.1  2  MFS_1       Major Facilitator Superfamily
    0.00067   18.1  10.3     0.0037   15.6   0.1    2.6  2  OATP        Organic Anion Transporter Polypeptide (OATP) fami


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.5  18.7     6e-27   5.4e-23       8     268 ..      64     343 ..      52     355 .. 0.78
   2 !    5.4  18.8   0.00081       7.3      67     169 ..     373     475 ..     364     487 .. 0.83

  Alignments for each domain:
  == domain 1  score: 81.5 bits;  conditional E-value: 6e-27
       MFS_1   8 salarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgagalfpag 106
                  +++ + +++++++  a+d g+s    ++ +    l+++++ +++ ++++ +Gr +++l++ +++ +++l +++++s++++  +r lqGl++ +   +g
  EEA22304.1  64 DGAMTWGATLIVTQ--AQDWGVSTNYSSTSMNYGILLQGFGGIFAVPFIEAYGRLPIWLWTQVVTMFMVLGATLSTSYPVFTTFRSLQGLFGTVPQVVG 160
                 33444444444444..88888888888888888889********************************55555856666******************** PP

       MFS_1 107 aaliadwfpkeergraigllsagfslGailgpllggllasslgWrav..fyilaivsllafvlfllllpeepperkrkspkeee............... 188
                 +++i d+f +++ +r+i +++++f +G+ lgp+++g+++ +  +r++  f +l++++ ++ ++++l+  e++ ++++++p  ++               
  EEA22304.1 161 LSIIHDMFDPKDWPRMINIWATTFLIGPFLGPAIAGYILVASQYRWIipFGVLTALYGVSTIMIMLFGHETYYDHENSRPNIKRpmmkriysfiglnnn 259
                 ************************************9986666666555**************99******************9***********9999 PP

       MFS_1 189 ..kgtgpaplvp....awkallkdpvlw..illialllfffgfsg...lltllplylqevlglsglllaglllallalvgailallagrls 268
                   + + ++ lv+    +wk++++ p l+  i +++ +++ +g++     + ++p y+ +    +        + +++++ga+++ ++g++ 
  EEA22304.1 260 ntHLDRRTTLVSesstLWKLIFRLPLLLtgINVMINFCWPIGITVtveSFLHSPPYMFDEIQAA-------SMRFAGVIGAASGYVFGYFF 343
                 9966666666667889*********775454444444444444445666666666644444444.......35555666666666666654 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.00081
       MFS_1  67 lglllfalglllll..fasslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGa.ilgpllggllasslgWravfyilaivs 161
                 ++l++ +++ + l+  f + +w  l++++v+  lg+ +++ a+ a++ + +p  + g + ++l++   +G   +g+  +++++   g  +vf + a+v 
  EEA22304.1 373 ASLAGGLVT-YGLTlnF-QRSWlGLAFGWVMVNLGMVGSTVAITAYALEKYPM-HSGPVSAILNMWRTCGGfSVGYFQASWIV-RNGVGVVFAVQAAVV 467
                 445555555.4444456.999989****************************8.***********988888799999999999.88999********** PP

       MFS_1 162 llafvlfl 169
                 ++++v+f+
  EEA22304.1 468 VVGVVIFI 475
                 **988643 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.1   4.1e-07    0.0037     134     192 ..     141     199 ..     131     203 .. 0.89
   2 !    8.0   1.6   8.3e-05      0.74      70     200 ..     211     353 ..     201     389 .. 0.59

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 4.1e-07
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 134 lfflaqlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslll 192
                 +f     l+G+ +t+ + +G+s i D  ++k+ p ++ i+ ++ ++Gp lG ++++++l
  EEA22304.1 141 VFTTFRSLQGLFGTVPQVVGLSIIHDMFDPKDWPRMINIWATTFLIGPFLGPAIAGYIL 199
                 566667799*99***************************************99999876 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 8.3e-05
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............xxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxx..xxxxx RF
        OATP  70 gigallmalgslllalPhfisgkyeyeeeesesekqk............krassssselcssekeekeesssk.lvllfflaqlllGiGatp..iytlG 153
                 g+ + l ++++++++l  f +++y  +e+++ + k +            +   +++++  ++ ++  +e ss+ + l+f l  ll Gi  +    +++G
  EEA22304.1 211 GVLTALYGVSTIMIML--FGHETYYDHENSRPNIK-RpmmkriysfiglN---NNNTH-LDRRTTLVSE-SSTlWKLIFRLPLLLTGINVMInfCWPIG 301
                 3344444444444333..43443333333333333.24677887764431...22222.2222222223.34558889999******9987533799** PP

                 xxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxx.xxxxxxx RF
        OATP 154 isYidDnvkkknsplyl.....gilyalrilGpalGfllGslllk.lyvdids 200
                 i+   ++  + + p+++     + + ++ ++G a G+++G+++++ +y + ++
  EEA22304.1 302 ITVTVESFLH-SPPYMFdeiqaASMRFAGVIGAASGYVFGYFFNEwIYKHYQQ 353
                 9987766543.344555777779999999**************9933444433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (489 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       784  (0.043728); expected 358.6 (0.02)
Passed bias filter:                      386  (0.0215294); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.32s 00:00:00.93 Elapsed: 00:00:00.48
# Mc/sec: 3087.82
//
Query:       EEA22305.1  [L=367]
Description: O-methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.8e-07   30.7   0.0      3e-07   30.0   0.0    1.3  1  Methyltransf_2   O-methyltransferase domain
      0.008   16.0   0.0      0.022   14.6   0.0    1.7  1  Methyltransf_23  Methyltransferase domain


Domain annotation for each model (and alignments):
>> Methyltransf_2  O-methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.0   0.0   3.3e-11     3e-07      66     208 ..     206     339 ..     199     341 .. 0.76

  Alignments for each domain:
  == domain 1  score: 30.0 bits;  conditional E-value: 3.3e-11
                     EEEET-TTSHHHHHHHHH-TT-EEEEEE-HHHHHHHHHHS.-----TTEEEEES-TTTS-----SEEEEESSGGGS-HHHHHHHHHHHHHH--TT CS
  Methyltransf_2  66 lvDvGGGtGalakaivsayPtikvivfDlpeVveaAkehl.sageeervefvgGdffkdslPeaDaillkrvlhDwsdekcvklLkrvkkalpag 159
                      vD+GGG G ++ +  +ayPt+    +    V ++ +  + s++e +++e+   +   +++  a  ++l+++ h   d +  +l+++v ka+ + 
      EEA22305.1 206 WVDIGGGRGEMLLELKEAYPTLMKEAL----VLQEFNPDIgSVPEVTQMEWNFASDTPQPVEGALNYSLSHIFHNLPDLNALELMQKVSKAMAPY 296
                     69******************9877765....55555555334444455554433333467778999***************************** PP

                     -EEEEEE----TTS---HHHHHHHHHHHHCSS-----HHHHHHHHHHCT CS
  Methyltransf_2 160 GkvivveavlgadpsgeletelvdlimlvqteGkeRteaeyeellseaG 208
                      ++i+ e   + +  g++++++     +   +G+ R+ ae+++l+   G
      EEA22305.1 297 SRLIIQEFTKN-KSYGKMHATM-----ITLYGGRLRSSAEWTRLAALCG 339
                     **999887654.4455555555.....33358************98766 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   2.5e-06     0.022      22     160 ..     202     340 ..     182     344 .. 0.66

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 2.5e-06
  Methyltransf_23  22 aggrvLdiGcGtGillevlrengf.....svtgvDlspeaveiaekakkaqkdqfdeqeaaepqg......kfdlIvlrevlehvpd..ppell 102
                      ++  ++diG G G++l +l+e         +++ + +p        ++ ++++ + ++e+ + ++           +l++ ++++pd    el+
       EEA22305.1 202 SDTVWVDIGGGRGEMLLELKEAYPtlmkeALVLQEFNP--------DIGSVPEVT-QMEWNFASDtpqpveGALNYSLSHIFHNLPDlnALELM 286
                      55689**************7753325666788888887........355667777.66666666622222233333778888888853366*** PP

  Methyltransf_23 103 rqiatllkpgGylllseplaslkedrllldwlylvpagrhisffsarslkelleeaGl 160
                      +++ + ++p  +l+++e++++     ++ ++++  +    +++ s+ ++ +l+   Gl
       EEA22305.1 287 QKVSKAMAPYSRLIIQEFTKNK----SYGKMHATMITLYGGRLRSSAEWTRLAALCGL 340
                      ******************8763....33333333333234455555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (367 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       377  (0.0210274); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2563.65
//
Query:       EEA22306.1  [L=183]
Description: hypothetical protein PMAA_060850 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.069   12.7   0.0       0.19   11.3   0.0    1.8  1  WHIM1     WSTF, HB1, Itc1p, MBD9 motif 1


Domain annotation for each model (and alignments):
>> WHIM1  WSTF, HB1, Itc1p, MBD9 motif 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   1.1e-05      0.19      14      30 ..      87     103 ..      82     103 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 1.1e-05
                 STCCCS-HHHHHHHHHH CS
       WHIM1  14 ggYyeLspeeklkiLki 30 
                 +++y L+peek+++L++
  EEA22306.1  87 RHFYYLTPEEKVQALRY 103
                 579************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (183 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       679  (0.0378716); expected 358.6 (0.02)
Passed bias filter:                      333  (0.0185733); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.40
# Mc/sec: 1377.39
//
Query:       EEA22307.1  [L=331]
Description: hypothetical protein PMAA_060860 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (331 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       683  (0.0380947); expected 358.6 (0.02)
Passed bias filter:                      473  (0.0263818); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2271.91
//
Query:       EEA22308.1  [L=545]
Description: hypothetical protein PMAA_060870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.5e-61  206.0   1.7    9.3e-61  205.7   1.7    1.1  1  Fungal_trans_2  Fungal specific transcription factor domain
  ------ inclusion threshold ------
      0.031   14.0   0.1      0.062   13.0   0.1    1.4  1  VPS28           VPS28 protein


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  205.7   1.7     1e-64   9.3e-61       2     366 ..      61     495 ..      60     544 .. 0.83

  Alignments for each domain:
  == domain 1  score: 205.7 bits;  conditional E-value: 1e-64
  Fungal_trans_2   2 lldyyldnvapllspvpes.snpfrkvllplalsnkallhallalsafhlqskgpkdslereakrykslalkelqealaelsstls.......rn 88 
                     ll+yy+  v+ + +  +++  np+r ++lp+a+++++l+ha la+sa  l   +p+   +  a+ +  +al+ l  +l++ +st +       +n
      EEA22308.1  61 LLSYYEAVVCSSSTLLDDAkNNPYRHLILPMAMQSEGLYHATLAVSAQILRIADPRF--RFAALDHGHRALRCLIASLQRGQSTPKytnhkqmSN 153
                     89*****************9******************************8888777..779999999****************99********* PP

  Fungal_trans_2  89 ekykdiLaaiLllcsieissgdvsdwrvhLeaatsliksrggskasssslsskarfllrifayldilssttlg...................... 161
                      + ++iL   L+lc++ei +g++ +w +hL++   li++++   +++s+ s   rf+ r+f+++ +l++tt++                      
      EEA22308.1 154 VEIDEILGLALMLCWFEITDGCRPSWVTHLKGIHTLINQYQDVFIKNSRTSDVSRFFSRYFSFHLVLARTTFRvedditftkttsskntgntekt 248
                     *************************************************************************6666666666666666666555 PP

  Fungal_trans_2 162 ..rgpsfpseeyekllen..kkeesdsgldplmGcsnslilliseisrLarekrsarkdseleplsileeaseleqrllswkprssdlepdldet 252
                        +++ ps + +  + +   + e+ +++d++mG+snsl+lli+e+++La++++s ++  e++    +e++ +l   l++++++  +l  + +  
      EEA22308.1 249 daIMQYYPSISKLTDFLSlaMPLEDLDQIDSYMGFSNSLLLLINEVADLAWKYHSKESV-ETDLPFVREQVWRLRASLETLQQTPPPLANNGRVN 342
                     5544444444444444449999999999*******************************.999999************99999988888888877 PP

  Fungal_trans_2 253 erassls...............kdltelfrlaaliylyrlv.......................lglpps....spevqelvkkllellellpss 305
                      +   +                + ++e+ r+ al+ l+ +                        +    +    + +++ +   l  +++ +   
      EEA22308.1 343 GASFYPFttgedellertvaefQAIAEANRIGALLLLHEVCasrfqrpdlfripmstetesadgY----HsastDYKTRYVREILDPMIQNINHI 433
                     777777799*******999999999*************877766677777666655555555443....05555555555555555555555555 PP

  Fungal_trans_2 306 pvaiasLlWplFiaGceavdeddRdfvrrrleele.qsrlgnvrrarqvleevWrrrddgee 366
                     ++  a  lWplFiaGc+ ++e+d+  v +++e++e  +r+gn++ arqv+e +Wr+rd+g +
      EEA22308.1 434 SRTAALPLWPLFIAGCCVTTEEDQITVIKIFEQTEkLKRYGNITPARQVIEMIWRQRDLGVQ 495
                     55344667**************************************************9876 PP

>> VPS28  VPS28 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.1   6.9e-06     0.062      32     120 ..     186     272 ..     180     316 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 6.9e-06
       VPS28  32 cnrLlsqyktilkdeevkkefksleeFvkky.kldcpaAlkRlkegvpatvehakakkskekkesaklvaeatqnFITlmDalkLnlkak 120
                 ++ L++qy+ ++    +++ + ++++F+++y  ++  +A++  +++ ++t ++++++k++ ++e++ ++++   +   l D l L +   
  EEA22308.1 186 IHTLINQYQDVF---IKNSRTSDVSRFFSRYfSFHLVLARTTFRVEDDITFTKTTSSKNTGNTEKTDAIMQYYPSISKLTDFLSLAMPLE 272
                 578********9...333334467777776536777888877777777777787888899999999999999888888888888776443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (545 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       365  (0.0203581); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.30s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 3547.83
//
Query:       EEA22309.1  [L=433]
Description: fructosyl amino acid oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.2e-46  159.9   0.0    1.4e-46  159.7   0.0    1.0  1  DAO             FAD dependent oxidoreductase
    4.6e-07   30.0   0.0      1e-06   28.9   0.0    1.6  1  NAD_binding_8   NAD(P)-binding Rossmann-like domain
    1.5e-06   27.7   0.1      0.056   12.7   0.0    2.7  3  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    0.00012   21.3   0.1      0.042   12.9   0.0    2.1  2  GIDA            Glucose inhibited division protein A
    0.00034   20.7   0.0    0.00091   19.3   0.0    1.6  2  Shikimate_DH    Shikimate / quinate 5-dehydrogenase
    0.00065   19.1   0.0      0.001   18.4   0.0    1.2  1  FAD_binding_3   FAD binding domain
     0.0014   18.7   0.1          1    9.3   0.0    2.4  2  NAD_binding_9   FAD-NAD(P)-binding
     0.0084   15.4   0.0      0.048   12.9   0.0    1.9  2  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
      0.012   15.3   0.0      0.023   14.3   0.0    1.5  1  ApbA            Ketopantoate reductase PanE/ApbA
      0.013   16.0   0.0       0.58   10.7   0.0    2.6  2  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
      0.024   14.0   0.0      0.041   13.2   0.0    1.2  1  ThiF            ThiF family
      0.047   14.0   0.0       0.12   12.6   0.0    1.7  1  TrkA_N          TrkA-N domain
       0.05   13.1   0.0      0.095   12.2   0.0    1.4  1  Glu_dehyd_C     Glucose dehydrogenase C-terminus
      0.089   13.2   0.0       0.16   12.5   0.0    1.6  1  NAD_binding_7   Putative NAD(P)-binding
      0.092   13.4   0.0        0.2   12.3   0.0    1.6  1  PglD_N          PglD N-terminal domain
      0.095   11.8   0.1       0.29   10.2   0.1    1.8  1  FAD_binding_2   FAD binding domain
        0.1   11.8   0.0       0.22   10.7   0.0    1.5  1  Thi4            Thi4 family
       0.11   11.9   0.0        4.3    6.6   0.0    2.2  2  GMC_oxred_N     GMC oxidoreductase
       0.14   11.0   0.1        6.5    5.5   0.0    2.1  2  Trp_halogenase  Tryptophan halogenase
       0.14   12.1   0.0       0.25   11.3   0.0    1.4  1  NAD_Gly3P_dh_N  NAD-dependent glycerol-3-phosphate dehydrogen
       0.18   12.6   0.0       0.37   11.6   0.0    1.5  1  GFO_IDH_MocA    Oxidoreductase family, NAD-binding Rossmann f


Domain annotation for each model (and alignments):
>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  159.7   0.0   1.6e-49   1.4e-46       1     351 [.       8     377 ..       8     378 .. 0.80

  Alignments for each domain:
  == domain 1  score: 159.7 bits;  conditional E-value: 1.6e-49
                 EEEEECTSHHHHHHHHHHHHTT...EEEEESSSSTTS.SGGGSSEEEEESSSSTHHSTHHHHHHHHHHHHHHHHHHHHHSSTTSEEEEEEEEEESSHHH CS
         DAO   1 dvviiGGGiiGlstAyeLarrg...Vtllekgdiags.gaSgrnsgllhsglrylpeaselarlslealeelreleeelgididyrrtGllslaadeee 95 
                 +++i+G+G +G stAy+L++rg   + +l+++  +++ +aS   s++++s + ++ +     ++  e+ e +r+++  +g+   y+ +G +  a +  +
  EEA22309.1   8 KILIVGAGAFGTSTAYHLSQRGyksIRVLDRHATPSCeAASTDISKVIRSDYNEPLY----CKMGIESTEAWRDWDMFQGL---YHVPGWILSACNL-S 98 
                 59*******************999**********9977************8764444....49*********999977774...9999999999765.4 PP

                 HHHHHHHHHHHHHTTTTE.EEEEHHHHHHHSTT.ST...TTSEEEEETTEEEEEHHHHHHHHHHHHHHTT-EEEESEC..EEEEEEEETCEEEEE.EEC CS
         DAO  96 lealdkllallleaglda.elldaeevrelepa.lp...gllgalfypdtgqvdpakltaalaraaealGveilegte..vtgleeedgkvwgve.rtt 186
                  + ++ +++  +++g++  e+l++e++re+ p  +    g+   +++p++g++   ++++ +a aae++Gve+++g +  v++l+    ++++ + + t
  EEA22309.1  99 VPFVEGSVETSKKLGVEGlEILTPEQIRERLPLvTGkldGWNINVWNPTAGWAKSGEALRRMALAAEKNGVEFITGDKgyVRKLKY-ASDGTTCKgVIT 196
                 77788888888889998879************973333466666********************************7677888843.333444445477 PP

                 T.EEEEEEEEEEE--GGGHH.HHHTTCTTTSEEEEEEEEEEEEEECCTHSTGSGCSEEEEEEEETTTTEEEEEETTSEEEEEESSE............. CS
         DAO 187 p.gendaadavVnaaGawsd.llgllkeldlpispvrgqvlvlkplseklvspaailpvpetdddgrgvyvtprkdgrvlvGgtad............. 270
                 + g++++ad v++aaGaw   l+    +l+     ++g++++  +l+ ++ +++a lp  + d+ + g+++ p +dg +++  +               
  EEA22309.1 197 QdGTVHEADLVILAAGAWMPsLI----DLQ-DQLTAKGHSVAHIQLTPAETKQYASLP--ILDNLELGYFFPPQEDGIFKLAHSQFitntttdpvsgit 288
                 87999888**********88444....442.337788888776344444444455555..58899*********9996666544446777777899998 PP

                 ......EETTCSSTSCSHHHHHHHHHHHHHHSGGGCG..EEEEEEEEEE.ETTSSEEEEEEETEEEEEEEEECTTTHHHHHHHHHHHHHH CS
         DAO 271 ......eesgdddpevdeedidellealrklfPqlgd..vlrkwaGlrp.lpdglpligetpgvkglylatGhsghGltlapatGkllae 351
                          +++d + + e  + +++ lr++fP+l+d  + +++ +  + + d+ +l+ ++pg ++l++atG s hG+++ p +Gk++a+
  EEA22309.1 289 tsiphtFVQSPTD-DLPLEIEATMRRNLRRVFPELADrpFCYTRLCWDAdTADRHFLVTPHPGQQNLFIATGGSAHGFKFLPIVGKYIAD 377
                 8887643333333.777888899***********977334456668888678********99999***********************98 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.9   0.0   1.2e-09     1e-06       1      42 [.      11      53 ..      11      78 .. 0.86

  Alignments for each domain:
  == domain 1  score: 28.9 bits;  conditional E-value: 1.2e-09
                   EE--SHHHHHHHHHHHCCTE.EEEEE-SSSSSSGGG-EECETT CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagf.dvlllekrdrlGGraasyevpg 42
                   IvGaG++G ++Ay+L+++g+ ++ +l+++  ++  aas ++ +
     EEA22309.1 11 IVGAGAFGTSTAYHLSQRGYkSIRVLDRHATPSCEAASTDISK 53
                   9*****************9966***********9999987754 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.7   0.0   0.00013      0.11     144     187 ..       8      53 ..       3      62 .. 0.72
   2 !   12.7   0.0   6.5e-05     0.056     188     237 ..     159     213 ..     151     230 .. 0.79
   3 ?   -1.4   0.0       1.3   1.1e+03     101     115 ..     352     369 ..     336     389 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00013
                  EEEEES-SHHHHHHHHHHHHHT-E.EEEEESSSSSS.TTS-HHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxx.xxxxxxxxx RF
  Pyr_redox_2 144 rivvvGgGyiGvElAaalaklgke.vtlveardrll.raldkelsa 187
                  +i++vG+G+ G+ +A +l++ g++ + ++++  ++  +a   ++s+
   EEA22309.1   8 KILIVGAGAFGTSTAYHLSQRGYKsIRVLDRHATPScEAASTDISK 53 
                  6888888888888888888888877777777766665666666655 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 6.5e-05
                  HHHHHHHHTTEEEEESCE..EEEEEETTE..EEE.EEETTSCEEEESEEEE-S-E CS
                  xxxxxxxxxxxxxxxxxx..xxxxxxxxx..xxx.xxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 188 aleealekeGvevklgts..vkeidgnge..kle.vvledgeeidadlvvvavGv 237
                  +++ a ek+Gve+ +g +  v +++  ++    + v+++dg++ +adlv++a+G 
   EEA22309.1 159 RMALAAEKNGVEFITGDKgyVRKLKYASDgtTCKgVITQDGTVHEADLVILAAGA 213
                  5677899********98744555555555446779******************96 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 1.3
                  SEEEE---EEE-BC...T CS
                  xxxxxxxxxxxxxx...x RF
  Pyr_redox_2 101 dklvlAtGssprdl...g 115
                  ++l++AtG+s++ +   +
   EEA22309.1 352 QNLFIATGGSAHGFkflP 369
                  6899****8776654244 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.3   0.0     0.005       4.3       1      28 [.       8      35 ..       8      55 .. 0.79
   2 !   12.9   0.0     5e-05     0.042     125     167 ..     186     230 ..     162     245 .. 0.83

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.005
                CEEEE-SSHHHHHHHHHHHHTT--EEEE CS
        GIDA  1 dviViGgGhAGceAAlaaarlGakvlLi 28
                ++ ++G+G  G+  A++++++G+k + +
  EEA22309.1  8 KILIVGAGAFGTSTAYHLSQRGYKSIRV 35
                589*******************997655 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 5e-05
                 T..TEEEEEEETTS-EEEECEEEE--TT-BT-EEEETTEEEESSC CS
        GIDA 125 e..kkvkgvvtedgetikakavviatGtflkgkihigekelsaGr 167
                 +  +++kgv+t+dg++ +a+ v++a+G+++ + i + ++ +++G 
  EEA22309.1 186 SdgTTCKGVITQDGTVHEADLVILAAGAWMPSLIDLQDQLTAKGH 230
                 344789***************************999999888886 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   0.0   1.1e-06   0.00091      13      47 ..       7      41 ..       3      56 .. 0.90
   2 ?   -3.1   0.0       8.7   7.4e+03      73      85 ..     201     213 ..     198     219 .. 0.80

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 1.1e-06
                  -EEEEES-SHHHHHHHHHHHCCT-CEEEEEESSHH CS
  Shikimate_DH 13 kkvlliGaGemaelvakhLlakgvkkvvvaNRtle 47
                   k+l++GaG  ++ +a hL+++g+k++ v+ R  +
    EEA22309.1  7 TKILIVGAGAFGTSTAYHLSQRGYKSIRVLDRHAT 41
                  79******************************865 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 8.7
                   HHT-SEEEE-SSS CS
  Shikimate_DH  73 laeadvvisatas 85 
                   ++ead+vi a ++
    EEA22309.1 201 VHEADLVILAAGA 213
                   7899999999887 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.0   1.2e-06     0.001       2      37 ..       7      43 ..       6      52 .. 0.90

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 1.2e-06
                   EEEEEE--SHHHHHHHHHHHHTTHH.EEEEESSSSSC CS
  FAD_binding_3  2 tdVlIVGaGpaGlmlallLseaGvr.vvlvekrsttv 37
                   t++lIVGaG  G ++a  Ls++G +  +++++++t +
     EEA22309.1  7 TKILIVGAGAFGTSTAYHLSQRGYKsIRVLDRHATPS 43
                   899********************87589*****9987 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.0    0.0012         1       2      42 ..      11      47 ..      10      59 .. 0.77
   2 !    6.9   0.0    0.0067       5.7     123     154 ..     178     212 ..     155     213 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.0012
  NAD_binding_9  2 ivGaGprGlavlerLlarakkkspleitlfdpsepgagrvw 42
                   ivGaG+ G++++ +L +r       +i + d++ + +  ++
     EEA22309.1 11 IVGAGAFGTSTAYHLSQRG----YKSIRVLDRHATPSCEAA 47
                   9****************95....667888888655435555 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0067
  NAD_binding_9 123 evvdleeradgq...avlladgaslaadaVvLAlG 154
                     v +l+ + dg     v+++dg+ ++ad V+LA G
     EEA22309.1 178 YVRKLKYASDGTtckGVITQDGTVHEADLVILAAG 212
                    5777777777743336999**************99 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.9   0.0   5.6e-05     0.048       1      31 [.      10      40 ..      10      44 .. 0.94
   2 ?   -0.3   0.0      0.58   4.9e+02     115     135 ..     194     214 ..     160     239 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 5.6e-05
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEkgn 31
                 +I+GaG+ G ++a++l + g +++ +l++++
   EEA22309.1 10 LIVGAGAFGTSTAYHLSQRGYKSIRVLDRHA 40
                 6***************************986 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.58
  Pyr_redox_3 115 evetsketyeAkkviiAtGef 135
                  +++++  + eA+ vi+A+G +
   EEA22309.1 194 VITQDGTVHEADLVILAAGAW 214
                  355555688999999999984 PP

>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   2.7e-05     0.023       1      32 [.       9      42 ..       9      73 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2.7e-05
                EEEES-SHHHHHHHHHHHHHTHC.EEEE-SCH.H CS
        ApbA  1 iailGaGaiGsllaakLakagad.vtlilrsr.r 32
                i+i+GaGa G+  a++L++ g++ + +++r +  
  EEA22309.1  9 ILIVGAGAFGTSTAYHLSQRGYKsIRVLDRHAtP 42
                89*****************888768888887753 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00068      0.58       1      47 [.       8      56 ..       8      62 .. 0.88
   2 ?    2.4   0.0      0.27   2.3e+02      46      62 ..     160     176 ..     154     199 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00068
                EEEEECSSHHHHHHHHHHHHTT.SEEEEEESSSSSS.TTSSHHHHHHHH CS
   Pyr_redox  1 kvvvvGgGyiglElAgalaelg.kkVtvversdkll.rllDeeaskilq 47
                k+++vG+G  g   A  l++ g k++ v++r+ ++   +   ++sk+++
  EEA22309.1  8 KILIVGAGAFGTSTAYHLSQRGyKSIRVLDRHATPScEAASTDISKVIR 56
                79********************7788*****999998888888888775 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.27
                 HHHHHHHTTEEEECSEE CS
   Pyr_redox  46 lqeklekngievllntk 62 
                 ++   ekng+e++++ k
  EEA22309.1 160 MALAAEKNGVEFITGDK 176
                 566689********976 PP

>> ThiF  ThiF family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   4.8e-05     0.041      18      50 ..       6      38 ..       5      40 .. 0.95

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 4.8e-05
                TSEEEEE--SHHHHHHHHHHHHHTTTEEEEEES CS
                xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        ThiF 18 dskvllvGaGglGsellknLalsGvgkltlvDn 50
                ++k+l+vGaG+ G   +  L   G +++++ D 
  EEA22309.1  6 NTKILIVGAGAFGTSTAYHLSQRGYKSIRVLDR 38
                689***************************996 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   0.00014      0.12       1      51 [.       9      61 ..       9      74 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 0.00014
                EEEES-SHHHHHHHHHHHH.TTEEEEEEESSHHH.HHHHHHTTSEEEES-TTS CS
      TrkA_N  1 iiiiGlGrvGrslaeeLse.ggkdvvvidkdeer.veelreeglevvvgdatd 51
                i+i+G+G +G+s a  Ls+ g+k++ v d+     +e ++ +  +v+  d+ +
  EEA22309.1  9 ILIVGAGAFGTSTAYHLSQrGYKSIRVLDRHATPsCEAASTDISKVIRSDYNE 61
                79*****************77799*****999773444444446677777654 PP

>> Glu_dehyd_C  Glucose dehydrogenase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00011     0.095      33      72 ..       8      45 ..       2      61 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00011
  Glu_dehyd_C 33 salvlGaGslGLLalalleaeerglervyvlgrrdrpdpt 72
                 + l++GaG+ G  ++ +l+  +rg++ + vl+r+ +p+ +
   EEA22309.1  8 KILIVGAGAFGTSTAYHLS--QRGYKSIRVLDRHATPSCE 45
                 579***********99997..69***********999865 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   0.00018      0.16       7      55 ..       6      59 ..       3     212 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00018
  NAD_binding_7  7 gkkvlvvGgGevAarkvrklleag.akvtvvapevkeele....elvklaeeel 55
                   + k+l+vG+G  +++ +++l + g + + v++   ++ +e    ++ k++++++
     EEA22309.1  6 NTKILIVGAGAFGTSTAYHLSQRGyKSIRVLDRHATPSCEaastDISKVIRSDY 59
                   5799********************7779**999987777655554444555554 PP

>> PglD_N  PglD N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   0.00024       0.2       1      35 [.       8      41 ..       8      64 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00024
      PglD_N  1 kivIiGaGGhgkvvadiieangeyeiigflDdnkk 35
                ki+I+GaG +g   a  + ++g y+ i +lD   +
  EEA22309.1  8 KILIVGAGAFGTSTAYHLSQRG-YKSIRVLDRHAT 41
                79********************.********8764 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.1   0.00033      0.29       2     203 ..       9     215 ..       8     273 .. 0.64

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00033
                    EEEE--SHHHHHHHHHHHHTTT.-EEEEESSSGGGS...GGGG--S-EE-TT..SSGGSTC.CHHHHHHHHHHHHT....TT-S.-HHHHHHHHHT CS
  FAD_binding_2   2 viViGsGlAGLaAAleaaeaGl.kvavvekeqefgg...atawsqGgidavlspeqkkagikdspelhrtdtlkal....dela.dqplveafvea 88 
                    ++++G+G+ G + A+ ++++G  ++ v++     ++   +t +s      +++p   k+gi+ ++ +  +d++++l    ++   + +l+  fve 
     EEA22309.1   9 ILIVGAGAFGTSTAYHLSQRGYkSIRVLDRHATPSCeaaSTDISKVIRSDYNEPLYCKMGIESTEAWRDWDMFQGLyhvpGWILsACNLSVPFVEG 104
                    79********************67777776665444555666666666666667777788866666666777777776666665555666666666 PP

                    HHHHHHHHHHTT----BCCTS.....SB-EEE-TT-SSTEEEE-.STT-......HHHHHHHHHHHHHHTCTEEEEE..SEEEEEEEECTT..EEE CS
  FAD_binding_2  89 apeavdeLeelgvpfsrtedg.....pvdvrelGglsatartlhdaadarretlvtghallarlvesarkagvdfqe..rteadeLivedg..rvt 175
                    + e  + L   g+ + + +++     p+   +l g++ +   ++ +++a    ++   + l r++ +a+k+gv+f +  + ++++L + ++   + 
     EEA22309.1 105 SVETSKKLGVEGLEILT-PEQirerlPLVTGKLDGWNIN---VW-NPTA---GWAKSGEALRRMALAAEKNGVEFITgdKGYVRKLKYASDgtTCK 192
                    66666666666666665.222333334444444444444...33.4443...67777777777777777777666642256677777743335777 PP

                    EEEEEETTTTCEEEEEESEEEE-----G CS
  FAD_binding_2 176 GavvenpesgrevrirakavvlatgGfg 203
                    G++ +   +g+ ++  a+ v+la+g++ 
     EEA22309.1 193 GVITQ---DGTVHE--ADLVILAAGAWM 215
                    76666...666554..677777777765 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00026      0.22      18      53 ..       7      42 ..       4      74 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00026
                EEEEEE--SHHHHHHHHHHHHCTTS-.EEEEESSSS- CS
        Thi4 18 sDvvivGaGssGLtaayylakkpdlk.vailersvsp 53
                + ++ivGaG+ G ++ay l+++ + k + +l+r+ +p
  EEA22309.1  7 TKILIVGAGAFGTSTAYHLSQR-GYKsIRVLDRHATP 42
                5799******************.55527788888665 PP

>> GMC_oxred_N  GMC oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   0.0     0.005       4.3       3      33 ..       9      39 ..       7      81 .. 0.82
   2 ?    3.2   0.0     0.055        47     190     258 ..     151     215 ..      91     220 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.005
  GMC_oxred_N  3 elveggGsagsvvAaRLsedpstsvlvleag 33
                  l++g+G++g+ +A+ Ls+ + +s+ vl+  
   EEA22309.1  9 ILIVGAGAFGTSTAYHLSQRGYKSIRVLDRH 39
                 79**********************9999754 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.055
  GMC_oxred_N 190 arqstarawLrpalerpnleiltgak..aekiilegrkkravGVeasdkkgtvkrlvvaakevvvaaGaln 258
                  a+++ a   +  a e++++e++tg k  ++k+ +   ++ + GV ++d        v++a+ v++aaGa +
   EEA22309.1 151 AKSGEALRRMALAAEKNGVEFITGDKgyVRKLKYASDGTTCKGVITQDGT------VHEADLVILAAGAWM 215
                  6888888888999999999**99864449999999999999999887754......559999*****9965 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0     0.033        28       1      31 [.       8      36 ..       8      54 .. 0.82
   2 ?    5.5   0.0    0.0077       6.5     163     208 ..     163     212 ..     151     224 .. 0.75

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.033
                    EEEEE--SHHHHHHHHHHHHHTTTSSEEEEE CS
  Trp_halogenase  1 kivivGGGtaGwlaAaalakalkgklevtlv 31
                    ki+ivG+G  G  +A +l++ + +  ++ ++
      EEA22309.1  8 KILIVGAGAFGTSTAYHLSQRGYK--SIRVL 36
                    79*****************99865..44444 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.0077
                     HHHHCT-EEEE--...EEEEEE-TTS.-EEEEEETTS-EEE-SEEEE-SG CS
  Trp_halogenase 163 vaearGvtrvegk...vvevqldedg.rveslrledgreveadlfiDcsG 208
                      ae++Gv+ + g+   v + +   dg   +++ ++dg++ eadl+i + G
      EEA22309.1 163 AAEKNGVEFITGDkgyVRKLKYASDGtTCKGVITQDGTVHEADLVILAAG 212
                     46777**999876222666667775526899***************9988 PP

>> NAD_Gly3P_dh_N  NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00029      0.25       1      32 [.       8      40 ..       8      66 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00029
                    -EEEE--SHHHHHHHHHHHTTT.--EEEE-S-H CS
  NAD_Gly3P_dh_N  1 kiavlGaGswGtalAkvlaeng.hevrlwvree 32
                    ki ++GaG++Gt+ A +l+++g +++r+  r++
      EEA22309.1  8 KILIVGAGAFGTSTAYHLSQRGyKSIRVLDRHA 40
                    789******************976777777665 PP

>> GFO_IDH_MocA  Oxidoreductase family, NAD-binding Rossmann fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   0.00044      0.37       2      45 ..       8      48 ..       7      67 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00044
                  EEEEETTSHHHHHHHHHHHHTTTTEEEEEEECSSHHHHHHHHHH CS
  GFO_IDH_MocA  2 rvaiiGaGkigskhlrplnesqrleevvalldpdaeraeavaes 45
                  +++i+GaG +g+  +  ++ sqr+++ + +ld++a  + ++ +s
    EEA22309.1  8 KILIVGAGAFGTSTA--YHLSQRGYKSIRVLDRHATPSCEA-AS 48
                  799**********97..999**************9988775.34 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (433 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       318  (0.0177366); expected 358.6 (0.02)
Passed bias filter:                      315  (0.0175693); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                        21  (0.00117129); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              21  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 2919.02
//
Query:       EEA22310.1  [L=511]
Description: allantoate permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-36  125.6  29.4    2.9e-36  125.1  29.4    1.2  1  MFS_1     Major Facilitator Superfamily
    0.00014   21.3   4.1    0.00014   21.3   4.1    2.2  2  MFS_4     Uncharacterised MFS-type transporter YbfB


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  125.1  29.4   3.2e-40   2.9e-36       1     353 []      71     436 ..      71     436 .. 0.87

  Alignments for each domain:
  == domain 1  score: 125.1 bits;  conditional E-value: 3.2e-40
       MFS_1   1 lllaaflsalarsilgpalpl.alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGl 97 
                 l++++++ a+   ++++++ +  +  d ++ + e++++ +++++g++v+ +p+++l++r+   ++l ++ll++a+  l+++ a++ +  l+ +r+l+G+
  EEA22310.1  71 LIMSTCVLAAVDKVIISNAAIyGMRADTHLVGNEYSWVGSIFYFGYLVFEYPAAFLIQRLPVAKFLSACLLGWAII-LMCTAATNDFaGLATVRFLMGM 168
                 5789999999999******999**************************************9999************.666646999989********** PP

       MFS_1  98 gagalfpagaaliadwfpkeergraigllsagfslGailgpllgglla.sslg...Wravfyilaivsllafvlfllllpeepperkrkspkeee.... 188
                  ++++fp++ ++++ w++ ee++  ++++  +++l++++  l++  +  ++ +   Wr++f++l+++++l++v++++++p++p++ +  +++e+     
  EEA22310.1 169 LESVVFPICSIFTVMWWTTEEQPIRLAFW--FNQLSSVFSGLVSYGIGhTHTSlppWRLLFIVLGAFTILWAVVVYFFMPDSPVTCWYLTDREKYvale 265
                 **************************887..78***************77777***************************************999**** PP

       MFS_1 189 ........kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvgail.allagrlsdrlgrrrrll 278
                         + +++ ++ +  ++ l+dp  w+l++ +l   + + gl+t+  ++ ++ lg+s   l++++l+++  v a + +l +++++ r+++ r ++
  EEA22310.1 266 rvknnntgVEDKKIKWYQ-VRECLTDPKTWLLVLFSLAQNIPNGGLVTFASII-VSGLGYS--SLITTVLGIPTGVLATVwQLALSFIAARFKNSRCIV 360
                 *99999999999999999.**********944444444456777799999997.*******..444444666655555555****************** PP

       MFS_1 279 lallllllaalglallavt.ssavllllvlvliGfglgfv.fpsllalasdlappeeagtasglfntagslggalgp 353
                 +al+ l+ ++++++++ ++ s+++ ll++++++ + +g +  +++l +a+ + + ++  t++++f +a+++g ++gp
  EEA22310.1 361 IALANLVPMTCAILMWKLPrSNQHGLLAAYYVFYTYWGPYvLSTSLPMANTS-GHSKKLTMNAVFFLAYCVGNIIGP 436
                 *******999999999999877777777777766655544144444444443.3466679****************8 PP

>> MFS_4  Uncharacterised MFS-type transporter YbfB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   4.1   1.5e-08   0.00014      18     123 ..      93     198 ..      89     252 .. 0.75
   2 ?    1.3   6.0     0.018   1.6e+02     211     359 ..     311     464 ..     305     468 .. 0.71

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 1.5e-08
       MFS_4  18 allaegqlslsqagllaaaNylGYLvGallaafalsagaeRlrllagllatvllllamaltesfaaflliRflaGvasAvvlvfgsslvlahaaaarre 116
                  ++a+++l  ++ ++++++ y GYLv    aaf  ++ +    l a ll  ++ l+  a+t+ fa ++ +Rfl G+   vv+ + s   +   +  +++
  EEA22310.1  93 GMRADTHLVGNEYSWVGSIFYFGYLVFEYPAAFLIQRLPVAKFLSACLLGWAIILMCTAATNDFAGLATVRFLMGMLESVVFPICSIFTVMWWTTEEQP 191
                 699***********************9999988888888888899999999999999*******************99999977776665554444444 PP

       MFS_4 117 rvgallf 123
                 + +a+ f
  EEA22310.1 192 IRLAFWF 198
                 4444444 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.018
       MFS_4 211 atFlvaiardgaggalleallWllvGlaaivgvlvwlrvakrsglrralaaall..ieavgvllsllsp.splglivssvllGltf..laitalvlqla 304
                  tF + i+   + ++l++  l + +G+ a v  l+   +a+r +++r++++al+  +   +++l   +p s    ++++  +  t+    + +  l++a
  EEA22310.1 311 VTFASIIVSGLGYSSLITTVLGIPTGVLATVWQLALSFIAARFKNSRCIVIALAnlVPMTCAILMWKLPrSNQHGLLAAYYVFYTYwgPYVLSTSLPMA 409
                 5788888888889999999999999999999999999***********999986224444444443332133333333333333430134555556666 PP

       MFS_4 305 relappatrrllglmTasfgigQilGpllasllaeatgslalallvaaaalvlaa 359
                       ++ ++ ++  +++ +g i+Gp  +  + + t s  +  l+a  ++++a 
  EEA22310.1 410 NTSGHSKKLTMNAVFFLAYCVGNIIGPQTFRSSDAPTYSHGYEGLLACLVVAIAC 464
                 55555555788889999************99999999888888888887777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (511 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       832  (0.0464053); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.50
# Mc/sec: 3098.40
//
Query:       EEA22311.1  [L=1325]
Description: 5-oxoprolinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   2.1e-198  659.9   0.3   2.9e-198  659.5   0.3    1.2  1  Hydantoinase_B  Hydantoinase B/oxoprolinase
   1.3e-105  352.9   0.2   4.6e-105  351.1   0.0    2.0  2  Hydantoinase_A  Hydantoinase/oxoprolinase
    7.2e-63  211.5   1.9    2.5e-61  206.5   0.0    2.5  2  Hydant_A_N      Hydantoinase/oxoprolinase N-terminal region
  ------ inclusion threshold ------
      0.025   14.3   0.0      0.051   13.3   0.0    1.5  1  Proteasome_A_N  Proteasome subunit A N-terminal signature


Domain annotation for each model (and alignments):
>> Hydantoinase_B  Hydantoinase B/oxoprolinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  659.5   0.3  6.4e-202  2.9e-198       1     515 [.     757    1289 ..     757    1290 .. 0.96

  Alignments for each domain:
  == domain 1  score: 659.5 bits;  conditional E-value: 6.4e-202
  Hydantoinase_B    1 DpitlevfrnrlmsiaeemgrtlqrtaiSpnikerlDfscalfdadgelvaqaphipvhlgsmseavkavlekfegelkpGDvlltNdPyagg 93  
                      Dpi+l+vf  r+ms+a++m+r+ q+t++S+nikerlDfsca+f++dg+lva+ap++pvhlgsm++av++++e+f+++l+pGD ++tN+P agg
      EEA22311.1  757 DPIRLSVFGYRFMSVADQMSRMFQKTSVSTNIKERLDFSCAVFSPDGKLVANAPNVPVHLGSMEYAVRYQHEQFADKLQPGDHICTNHPLAGG 849 
                      9*************************************************************************99***************** PP

  Hydantoinase_B   94 tHlpDitvitPvfhege..lvffvasraHhaDiGGitpGsmppdateifeEGlrippvklveegeleedvle.lllanv.........Rtped 174 
                      tHlpDit+itPv   +   ++f+vasr+Hha+iGGi+pGsmp++++ ++eEG++   +k+v+e++ +ed+++ +l +++         Rt +d
      EEA22311.1  850 THLPDITIITPVWDAEGkqIIFYVASRGHHAEIGGIQPGSMPSNSRLLYEEGAMTMGFKIVSEDRFNEDIVRkFLYDEPasfpgcsgtRTWND 942 
                      ************9654479**********************************************77777652777777************** PP

  Hydantoinase_B  175 nlgDlkAqiaanqvgerrlkelieeyGldtveaamdeildnaeravraalaelpd....gtyeaedylddgipikvtvtidgde..atvDftg 261 
                      n++DlkA iaanq+g+++l+ l+ee +l++v+ +md i dnae avr+ l+++ +    + ++++d++ddg++i+++++id ++  a +Dftg
      EEA22311.1  943 NVSDLKAAIAANQKGATLLRGLVEENSLQVVHFYMDGIKDNAEVAVREYLKKVGKqtggKPLKFSDFMDDGTEIRLEIRIDTETgsADFDFTG 1035
                      *****************************************************9999977799*****************999999******* PP

  Hydantoinase_B  262 tspqvkgniNaplavtlsaviyvlrclvdediplNeGclrpievklpegsllnpsepaavvggnvetsqrvvdvvlkalaqalpervaAasqg 354 
                      t++++ + +Nap+a+++sa+iy lrcl++ diplN+Gcl+p++v++p g+llnps +aav++gn  tsqr++dvvl+a++      ++Aasqg
      EEA22311.1 1036 TGRETFNCLNAPKAIAHSAIIYSLRCLINVDIPLNQGCLAPCNVIIPSGTLLNPSGNAAVCAGNPITSQRITDVVLGAFN------ACAASQG 1122
                      ********************************************************************************......******* PP

  Hydantoinase_B  355 tmnnltf..ggvderg..geffgyyetiagGaGArpgkdGasavhvhmtntrntdvEilErryPvlverfelrpdsgGaGkyrGGdGvvreie 443 
                      ++n++ f  gg+d++g     fg+ eti+gG+GA+pg++G+savh+hmtntr+td+E+ E ryPv++++f++r++sgG+G+y+GG+G vre+e
      EEA22311.1 1123 CCNIISFgmGGMDKDGnvVPGFGVGETICGGSGAGPGWNGTSAVHCHMTNTRITDAEVYELRYPVILRQFSIRQGSGGRGQYNGGNGSVRELE 1215
                      ****998334666655995566*********************************************************************** PP

  Hydantoinase_B  444 flepevtvsilserrvfapwGlaGGepGargrvvlnllvr......geeenlggkatvelkagdvlvietpGGGGyGd 515 
                      f+ p ++vs+lserrv++p+G+aGGepG++g    nl vr      ++++n+ggk ++++++g++++i++pGGG +G+
      EEA22311.1 1216 FRIP-LSVSMLSERRVYRPYGMAGGEPGQAGL---NLYVRkehdgsERTINIGGKMELNVQPGERIIINSPGGGAWGS 1289
                      ***9.***************************...66666677788*******************************6 PP

>> Hydantoinase_A  Hydantoinase/oxoprolinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1      0.25   1.1e+03      81      99 ..      16      34 ..       8      37 .. 0.83
   2 !  351.1   0.0    1e-108  4.6e-105       1     290 [.     255     550 ..     255     551 .. 0.97

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.25
  Hydantoinase_A 81 vItfDmGGTstDvslikdg 99
                     I +D GGT tD+  i +g
      EEA22311.1 16 KIAIDRGGTFTDCLGIVEG 34
                    5899********9999877 PP

  == domain 2  score: 351.1 bits;  conditional E-value: 1e-108
  Hydantoinase_A   1 rtetavvnAylspilreylesvekslekrgak..arlmvmqsdGglvsadearkkpvetilSGPaaGvvgaaat.sklagekkvItfDmGGTstD 92 
                     r+ +a+ +Ayl+p++r+y++++++ +++   +  +r+ +mqsdGglv+++++++   ++ilSGPa+Gvvg a+t  + a+ ++vI+fDmGGTstD
      EEA22311.1 255 RGASATADAYLTPVIRRYIDGFRSGFKDGLRSedTRCEFMQSDGGLVNFEKFSGL--RAILSGPAGGVVGHARTsFDPADPRPVIGFDMGGTSTD 347
                     78899**********************966556699******************9..*****************667788899************ PP

  Hydantoinase_A  93 vslikdgevevsleteiagvkvrlpaldirtvgagGgsilvvdeggklrvgpesagadpgpacyrkGgteltvTDanlvLGrlqpedfls..gpd 185
                     vs+++ g++e+++e ++agv++ +p+ldi+tv+agGgs+l +++ g + vgp+saga+pgpacyrkGg +ltvTDanl+LGrl pe+f++  gp+
      EEA22311.1 348 VSRYD-GKFEHTFENTTAGVTIMAPQLDINTVAAGGGSVL-FWRHGLFVVGPDSAGAHPGPACYRKGG-PLTVTDANLFLGRLLPEYFPKifGPN 439
                     *****.**********************************.***************************.************************** PP

  Hydantoinase_A 186 gdqkldvelarrafeelakelnlk......veevAegilsvavenmanavrklsvergldpkeltlvvfGGaGaqhaaalaeelgvkkvivppya 274
                     +++ ldve++r++f+ela +++++      +ee+A g+++va+e ma+++r l+++rg++++ ++l++fGGaG+qha+a+a +l +++vi+++y+
      EEA22311.1 440 ENEALDVEITRQKFTELARQIQEEtgqaksPEEIALGFIEVANESMAKPIRALTEARGYETSAHNLACFGGAGGQHACAIATSLSIQTVIIHRYS 534
                     *********************999*********************************************************************** PP

  Hydantoinase_A 275 gvlsalGmalAdvree 290
                     ++lsa+GmalAdv +e
      EEA22311.1 535 SILSAYGMALADVVHE 550
                     *************987 PP

>> Hydant_A_N  Hydantoinase/oxoprolinase N-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  206.5   0.0   5.6e-65   2.5e-61       1     178 []      16     236 ..      16     236 .. 0.96
   2 !    3.7   0.6    0.0098        44       2      19 ..     337     354 ..     336     369 .. 0.83

  Alignments for each domain:
  == domain 1  score: 206.5 bits;  conditional E-value: 5.6e-65
  Hydant_A_N   1 rigIDvGGTfTDavaldekeeevavlKllst.....pdavaegirealeevleesipr.......tskidvvrmGTTvatNallerkgervaLittkgf 87 
                 +i+ID+GGTfTD++ + e++e  +v+Klls+      da++egir++le++++++ pr       +    ++rmGTTvatNallerkg+rvaL++tkgf
  EEA22311.1  16 KIAIDRGGTFTDCLGIVEGREDDIVVKLLSQdpsnyADAPIEGIRRILEQATGKPFPRseklstgDFSSVSIRMGTTVATNALLERKGDRVALLITKGF 114
                 69*****************9**************************************888885533334689************************** PP

  Hydant_A_N  88 rdlleigrqnrpdlfelrikkplvlyeevvevdervead...............................gevlkpldeeevrealkalkaagvesiav 155
                 +d+leig+q+rp+lf+l+i++p vlyeevvevderv+++                               ++vl++lde++vr++l++l+++g++siav
  EEA22311.1 115 KDALEIGNQSRPHLFDLNIRRPDVLYEEVVEVDERVTIEdyqqnptpnkealaasldsdpqltrgvsgevVRVLEKLDEDKVRKDLQSLYEKGYRSIAV 213
                 **************************************99*********************************************************** PP

  Hydant_A_N 156 vllhSylnpehElrvaeiareig 178
                 vl+hSy++ +hEl++++ia+e+g
  EEA22311.1 214 VLVHSYTFQDHELAIERIAKEVG 236
                 ********************985 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.0098
  Hydant_A_N   2 igIDvGGTfTDavaldek 19 
                 ig D+GGT TD+  +d+k
  EEA22311.1 337 IGFDMGGTSTDVSRYDGK 354
                 899********9888865 PP

>> Proteasome_A_N  Proteasome subunit A N-terminal signature
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   1.1e-05     0.051       2      14 ..     793     805 ..     793     806 .. 0.96

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.1e-05
  Proteasome_A_N   2 DrslttFSPdGRL 14 
                     D+s+ +FSPdG+L
      EEA22311.1 793 DFSCAVFSPDGKL 805
                     9***********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1325 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       605  (0.0337442); expected 358.6 (0.02)
Passed bias filter:                      581  (0.0324056); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.91u 0.31s 00:00:01.22 Elapsed: 00:00:00.48
# Mc/sec: 8220.82
//
Query:       EEA22312.1  [L=581]
Description: beta-mannosidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
     0.0033   17.3   0.0     0.0073   16.2   0.0    1.5  1  Glyco_hydro_2_N  Glycosyl hydrolases family 2, sugar binding 
     0.0036   17.9   0.0       0.01   16.5   0.0    1.8  1  Mannosidase_ig   Mannosidase Ig/CBM-like domain
  ------ inclusion threshold ------
      0.022   14.9   0.0      0.093   12.9   0.0    2.0  2  Ig_GlcNase       Exo-beta-D-glucosaminidase Ig-fold domain
      0.037   13.8   0.0      0.084   12.6   0.0    1.6  1  Ig_mannosidase   Ig-fold domain


Domain annotation for each model (and alignments):
>> Glyco_hydro_2_N  Glycosyl hydrolases family 2, sugar binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   1.6e-06    0.0073      80     124 ..      76     120 ..      53     154 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.6e-06
                      HHSEEEEEESEEESEEEEEETTEEEEEEE-TTS-EEEEGGGGS-S CS
  Glyco_hydro_2_N  80 aekkvrllFegvtsasevwvngqevgkrqgsylpfefDltpylse 124
                       +k+v+l Feg ++   v +ng+++ k ++ ++pf +D+++ l e
       EEA22312.1  76 GHKHVELFFEGLDTFATVILNGEQIAKSENQFIPFPADVSKTLVE 120
                      345899*********************************997765 PP

>> Mannosidase_ig  Mannosidase Ig/CBM-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   2.2e-06      0.01      36      95 .]     443     497 ..     420     497 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 2.2e-06
  Mannosidase_ig  36 ttpvtvgansstevaeidvdellaatggadpravvlvarledatgevlatnvywpvplKd 95 
                     + +v++ + + t++ +++ ++ +      + + ++l+a l d +g+v+a+ v+wp+p+++
      EEA22312.1 443 SRQVSLLPGQNTDLGTLTNPSAV-----DADSLIILSANLIDGNGAVVARFVDWPEPFRY 497
                     56777777777777777777554.....34777899**********************98 PP

>> Ig_GlcNase  Exo-beta-D-glucosaminidase Ig-fold domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0      0.91   4.1e+03      72      84 ..     446     458 ..     441     486 .. 0.64
   2 ?   12.9   0.0   2.1e-05     0.093      67      88 ..     545     566 ..     542     572 .. 0.88

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.91
  Ig_GlcNase  72 vtLlPgEsltltv 84 
                 v+LlPg++++l  
  EEA22312.1 446 VSLLPGQNTDLGT 458
                 6777777666644 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 2.1e-05
  Ig_GlcNase  67 wsDNyvtLlPgEsltltveypa 88 
                 w+DN v LlPg++++++v++ +
  EEA22312.1 545 WEDNMVDLLPGDKVQVRVKCLE 566
                 ******************9855 PP

>> Ig_mannosidase  Ig-fold domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   1.9e-05     0.084      18      60 ..     521     564 ..     504     577 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.9e-05
  Ig_mannosidase  18 kvtlsadavAlfVwLe.lsgvdgrFsdNgFdLlpgesktvtftv 60 
                     +v+++++++ +   L+  sg    ++dN  dLlpg +++v+++ 
      EEA22312.1 521 TVEIESNNPIKGFLLDvESGEMPEWEDNMVDLLPGDKVQVRVKC 564
                     799999*****999**77777778****************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (581 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       353  (0.0196888); expected 358.6 (0.02)
Passed bias filter:                      301  (0.0167884); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.41
# Mc/sec: 4219.38
//
Query:       EEA22313.1  [L=346]
Description: oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      4e-19   69.6   0.0    6.7e-19   68.9   0.0    1.3  1  GFO_IDH_MocA     Oxidoreductase family, NAD-binding Rossmann 
     0.0031   17.8   0.0     0.0053   17.0   0.0    1.4  1  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma
  ------ inclusion threshold ------
      0.016   15.6   0.0      0.037   14.5   0.0    1.6  2  Semialdhyde_dh   Semialdehyde dehydrogenase, NAD binding doma


Domain annotation for each model (and alignments):
>> GFO_IDH_MocA  Oxidoreductase family, NAD-binding Rossmann fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.9   0.0   1.1e-22   6.7e-19       2     107 ..       4     117 ..       3     128 .. 0.94

  Alignments for each domain:
  == domain 1  score: 68.9 bits;  conditional E-value: 1.1e-22
                   EEEEETTSHHHHHHHHHHHHTTTTEEEEEEECSSHHHHHHHHHHTTHEEESS........HHHHHTCTTESEEEE-S-GGGHHHHHHHHHHTT-EEE CS
  GFO_IDH_MocA   2 rvaiiGaGkigskhlrplnesqrleevvalldpdaeraeavaesfgveaysd........leelladpeidavivatpngtheelakaaleagkhvl 90 
                    vai GaG +g+++  p  + ++ + + a+++++++++ ++ e+ gv+ay d        l++ll+ ++idavi+a p + + ++++aa +agkhvl
    EEA22313.1   4 GVAILGAGLFGKDQYLPAVKGSSSYTLKAVYSRSQKSSTKLGEEAGVDAYYDnpetpdrsLSNLLERSDIDAVIIALPITVQPDIIRAAWKAGKHVL 100
                   69********999999999999**************************88888******************************************** PP

                   EESSS-SSHHHHHHHHH CS
  GFO_IDH_MocA  91 lEKPlattveeakelve 107
                    EKP+a + + a++l++
    EEA22313.1 101 SEKPVAKDSTGARQLIA 117
                   ********999999986 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0   8.8e-07    0.0053       1     120 [.       5     133 ..       5     137 .. 0.74

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 8.8e-07
                      EEEE--SHHHHH.HHHHHHCTCCT-GEEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHHHTTS..SEEEE-SSGGGHHHHHHHHHH CS
  Sacchrp_dh_NADP   1 vliiGaGsvGqa.vaellarhfdvdaeitvadrskeklealaakalgvrfeaialdaenyeavLaallkeg..dlvvnlsppissldvlkaCie 91 
                      v i+GaG  G+   ++ ++ ++++ +  +v +rs+++  +l     +  ++a+  ++e ++  L+ ll+    d+v+ ++p +   d+++a+++
       EEA22313.1   5 VAILGAGLFGKDqYLPAVKGSSSY-TLKAVYSRSQKSSTKLG---EEAGVDAYYDNPETPDRSLSNLLERSdiDAVIIALPITVQPDIIRAAWK 94 
                      568888888875145555555555.36688899999988887...56799999999***************99********************* PP

                      HT-EEEE........SS-...BCGCCSCHCCSHHHHHTHH CS
  Sacchrp_dh_NADP  92 tgvhyvd........tsi...skeertnyalreavlklke 120
                      +g h++         t       +  ++y+ + +v++ +e
       EEA22313.1  95 AGKHVLSekpvakdsT-GarqLIADYEPYKAKGQVWAVAE 133
                      *****98765444441.03332334466666666666655 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.0   6.2e-06     0.037       2      94 ..       5     100 ..       4     107 .. 0.86
   2 ?   -3.3   0.0         2   1.2e+04      92     113 ..     127     148 ..     109     150 .. 0.70

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 6.2e-06
                     EEEETTTSHHHHHH.HHHHHCTSSEEEEEEEESTTTTTSBHHHHSGGGTTTECEBEEEGGGGGC...TT-SEEEE-SCHHHHHHHHHHHHHTTSE CS
  Semialdhyde_dh   2 vaivGatGyvGqel.lrlLeehpevelvvllsssrsaGkklaeavkaleegkdlkvedvdeeel...kevdivflalpagvskelapklaeagvk 92 
                     vai+G  G  G++  l  ++ + +++l +++s+s++  +kl e ++  +++ + +  d +  +l   +++d v+ alp  v  ++ +++ +ag +
      EEA22313.1   5 VAILG-AGLFGKDQyLPAVKGSSSYTLKAVYSRSQKSSTKLGEEAGVDAYYDNPETPDRSLSNLlerSDIDAVIIALPITVQPDIIRAAWKAGKH 98 
                     899**.799998764888999***********************9*8888888888874444444559*************************99 PP

                     EE CS
  Semialdhyde_dh  93 vi 94 
                     v 
      EEA22313.1  99 VL 100
                     86 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 2
                     EEEESSSTTTTSTTSEBE-HHH CS
  Semialdhyde_dh  92 kviDlssdfRlkddavyvlpev 113
                     +v   + +fR+ d ++y+ +++
      EEA22313.1 127 QVWAVAENFRFIDPITYGTAQL 148
                     4556778889888888887766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (346 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       253  (0.0141112); expected 358.6 (0.02)
Passed bias filter:                      243  (0.0135535); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.43u 0.23s 00:00:00.66 Elapsed: 00:00:00.38
# Mc/sec: 2731.50
//
Query:       EEA22314.1  [L=255]
Description: maltose permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.7e-12   44.5   0.8    1.3e-11   44.0   0.8    1.1  1  Sugar_tr  Sugar (and other) transporter
  ------ inclusion threshold ------
      0.037   14.4   0.6       0.16   12.3   0.2    2.1  2  DUF4149   Domain of unknown function (DUF4149)


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.0   0.8   1.5e-15   1.3e-11     361     449 ..     113     204 ..     110     206 .. 0.93

  Alignments for each domain:
  == domain 1  score: 44.0 bits;  conditional E-value: 1.5e-15
                 HHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH...T-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCG CS
    Sugar_tr 361 alfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfpiiteaig...ggyvflvfaglavlfiifvfffvpetkgrtleeie 449
                 +++++ +g + + l++E+ ++ +R+++++i+ +++ +   ++++++p+i +  +   g+++++vf gl +++ + vf+ +petkg+ ++ei+
  EEA22314.1 113 IFYQIAIGAIGFALSAEVGSLPLRPVTQSIVGVTQGVTGWVMGFVTPYIINPDEgnlGAKIGFVFFGLGIIASVLVFLYIPETKGLNFDEID 204
                 59*********************************************99875555666********************************97 PP

>> DUF4149  Domain of unknown function (DUF4149)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.17   1.6e+03      35      58 ..     108     131 ..      92     140 .. 0.79
   2 ?   12.3   0.2   1.7e-05      0.16       3      60 ..     143     196 ..     141     220 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.17
     DUF4149  35 sklFplyfglglalsvllllteva 58 
                 ++  p+++++ ++  +++l  ev 
  EEA22314.1 108 HRCLPIFYQIAIGAIGFALSAEVG 131
                 445899999999999999988875 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 1.7e-05
     DUF4149   3 lglllGsqlwvtfvvapvlfrsLprhqfgelqsklFplyfglglalsvlllltevavg 60 
                 +g++ G+++wv  +v+p++       + g+l +k+  ++fglg++ svl+ l+ +  +
  EEA22314.1 143 VGVTQGVTGWVMGFVTPYIINP----DEGNLGAKIGFVFFGLGIIASVLVFLYIPETK 196
                 68889*************9987....68************************988655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (255 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       621  (0.0346366); expected 358.6 (0.02)
Passed bias filter:                      486  (0.0271069); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.23s 00:00:00.68 Elapsed: 00:00:00.39
# Mc/sec: 1938.43
//
Query:       EEA22315.1  [L=529]
Description: pantothenate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-33  116.0  25.5    1.7e-33  116.0  25.5    1.7  1  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.0  25.5   9.6e-38   1.7e-33       2     347 ..      79     440 ..      78     447 .. 0.84

  Alignments for each domain:
  == domain 1  score: 116.0 bits;  conditional E-value: 9.6e-38
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.sslw.lllvlrvlqGlg 98 
                 +l++f+  l+ ++++ a+ + +++dl++ + ++++  t++  g +v+++pl  ls+ + +  ++ ++ l++++  ++++ a +  + +++ lr++ G++
  EEA22315.1  79 ALSIFIKNLDNTNISNAYVSGMQTDLHLYGNQLNIFGTMFNCGIIVGAVPLILLSTHIRPSILMPTCELCWSIL-VMGI-AgAKDYqTIYGLRFFIGFF 175
                 67889999999999999999**************************************7777************.5555.3366666************ PP

       MFS_1  99 agalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg......Wravfyilaivsllafvlfllllpeepperkrkspkeee... 188
                 ++++fp+ a+l+a+w+++ e g+ ++++ ++ +++ ++   + + l+++ +      Wr++f++ +i+sl  ++   + +++ p ++k ++ + +    
  EEA22315.1 176 EAIAFPGFASLLAAWYTPAELGKRMAIYEVSQNVAGMFSGYIQAGLYAHMNgrglasWRWLFIFDGIISLPIAI---WGFWAIPDQPKDSKAWWLDced 271
                 ***********************************************88888********************99...9999999999999999999*** PP

       MFS_1 189 ..........kgtgpaplvp....awkallkdpvlwillialllfffgfsg.lltllplylqevlglsglllaglllallalvgailallagrlsdrlg 272
                           +  g++pl++     +k ++k  ++  +l++++++f g ++   +++ l+lq+  ++s +  +  ++ +++ ++++ ++l+g++sd l 
  EEA22315.1 272 rtiaiermdrV--GRKPLKKvnwtRFKGIWKTWHV--YLFVICYVFYGAFSwGDSYFGLWLQSLNKYS-VENINNIPTAGQGAAVVNSILSGFISDWLV 365
                 ********663..4444444433336666666666..555555555555555899999999999****.555555599999999999**********87 PP

       MFS_1 273 rrrrlllallllllaalglallavtssavllll...vlvliGf.glgfvfpsllalasdlappeeagtasglfntagsl 347
                 +  r l+++  +++++lg a+lav + +++l +   ++++ G+ +++++++ l  +++ +a    +g ++++ nt+ ++
  EEA22315.1 366 N--RPLMIITNMMICLLGNAFLAVWTAPTALKFvgyIFITTGLpAQSLTMTWLSEVCQGNA--TLRGLIVSIGNTFIYA 440
                 7..7777777888888888888887444444444457777*********************..**********987654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (529 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       712  (0.0397122); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.39
# Mc/sec: 4037.94
//
Query:       EEA22316.1  [L=278]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (278 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       491  (0.0273858); expected 358.6 (0.02)
Passed bias filter:                      187  (0.01043); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.29s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 1895.13
//
Query:       EEA22317.1  [L=378]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.5e-06   25.8   2.1    8.4e-06   25.2   2.1    1.2  1  DUF4185   Domain of unknown function (DUF4185)


Domain annotation for each model (and alignments):
>> DUF4185  Domain of unknown function (DUF4185)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   2.1   4.7e-10   8.4e-06     164     300 ..     222     359 ..     183     373 .. 0.78

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 4.7e-10
     DUF4185 164 vkddgyvYvfgtpngRsgaayLarvpeadildlsayeywkgggeaWvkaeea.aatpvl...agpvgElSvqyneklgkwvllyld..eeknsivlrta 256
                 v ++g+ Y++g+++   g + La+v  + ++++say+y+ +g+  W+++ ++ + t v    ag+ g  ++ y +  +k+v + +   + + +  + ta
  EEA22317.1 222 VVNNGVAYLYGKNA--AGTVGLAKVSTRFVTNKSAYQYYVNGA--WTPNVPGvNDTGVGipnAGAGGQGTFYYSSVWNKYVWIGQAgiSVSPAFFITTA 316
                 4589999****987..699********************8777..****99943444445565557888888888889988887663345578899*** PP

     DUF4185 257 dspegpwsepktlvssaqvpglYgpyihPwstlksktgkdlyfl 300
                 +spegpw +p    s++ ++  Y    hP+   +s +++ +y+ 
  EEA22317.1 317 PSPEGPWATPVNFYSANYINWSYTLQAHPGLLANS-SQNAIYLS 359
                 **************8777777*********77666.66676653 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (378 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       300  (0.0167327); expected 358.6 (0.02)
Passed bias filter:                      220  (0.0122706); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.40
# Mc/sec: 2801.43
//
Query:       EEA22318.1  [L=243]
Description: oxidoreductase, short-chain dehydrogenase/reductase family, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.5e-53  179.5   0.0    9.1e-53  179.2   0.0    1.0  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    3.1e-46  157.3   0.0    3.9e-46  157.0   0.0    1.1  1  adh_short        short chain dehydrogenase
    3.3e-10   40.2   0.0    4.9e-10   39.6   0.0    1.2  1  KR               KR domain
  ------ inclusion threshold ------
      0.013   14.7   0.0      0.018   14.2   0.0    1.2  1  Polysacc_synt_2  Polysaccharide biosynthesis protein
      0.071   12.5   0.0       0.11   11.9   0.0    1.1  1  DUF1776          Fungal family of unknown function (DUF1776)
        0.1   13.3   0.0       0.23   12.1   0.0    1.6  1  Phage_ABA_S      Phage ABA sandwich domain
       0.13   11.7   0.0       0.36   10.2   0.0    1.8  1  Epimerase        NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  179.2   0.0   3.5e-56   9.1e-53       3     231 ..      14     240 ..      10     242 .. 0.93

  Alignments for each domain:
  == domain 1  score: 179.2 bits;  conditional E-value: 3.5e-56
                   TTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSE.E..EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHH CS
  adh_short_C2   3 asgIGraiAkalaeeGaevvltdlneeakkrveelaeelgae.v..lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreefd 96 
                    +gIGra+A+++ + Ga+vv+ + +++a  +++e++++lg++ v   ++D+ + +  +++v+e+v++fgk+Dil+ nag++p   ++++ ++++ fd
    EEA22318.1  14 SKGIGRAVAEQFVALGAKVVINYSSDSA--AADEVVQKLGRDnVlsTKADAGSVAGTKQIVDEAVARFGKIDILIPNAGWMPM--ANLEAVTEDLFD 106
                   58*************************9..899*******887779*************************************..************ PP

                   HHHHHHTHHHHHHHHHHHHHCTSCCEEEEEEEG..GGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTTHHHHHHH CS
  adh_short_C2  97 raldvnlyslfllakaalplmkeggsivnlssv..gaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikgfdellee 191
                   r+ ++n+++ + lakaa+p+m eg+ iv +s    +a  ++p +  y+ +K+a+e++tr l ++l+pkgi vN+v+pgp++T++  + k  d+l ++
    EEA22318.1 107 RIYEINVKGPLFLAKAAVPHMPEGSHIVFISTSlcHAGTIMPPQLLYCSTKGAIEQFTRMLSRDLAPKGIVVNCVAPGPTATELFMRGK-PDALVDA 202
                   ***************************999655226667799999***************************************66554.79***** PP

                   HHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEEST CS
  adh_short_C2 192 learaplgrlgtpeevaeaalfLasdeasyitGqtlvvDg 231
                   +++++p++rlgtpee+aea++++    +s++ Gqtl v+g
    EEA22318.1 203 IKKQSPFNRLGTPEEIAEAIVYMSG--TSWVAGQTLKVNG 240
                   **********************975..78********998 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  157.0   0.0   1.5e-49   3.9e-46       1     189 [.       6     193 ..       6     198 .. 0.94

  Alignments for each domain:
  == domain 1  score: 157.0 bits;  conditional E-value: 1.5e-49
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCSH CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvv.vdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfselse 98 
                 kv+++tG+s+GIGra+a+++++ Gakvv+ +++ ++++ ev+++l++  +++l  ++D  + + ++++v++av+++gk+d+L+ NAG   +++ + ++e
  EEA22318.1   6 KVAVITGGSKGIGRAVAEQFVALGAKVVInYSSDSAAADEVVQKLGR--DNVLSTKADAGSVAGTKQIVDEAVARFGKIDILIPNAGWMPMANLEAVTE 102
                 89***************************999999***********8..58************************************************ PP

                 HHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TT..BHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHH CS
   adh_short  99 eewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvag..vaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmake 189
                 + ++r++e+N++g++ l++a++p+m   ++ +Iv++s   ++ + ++  +  Y+++K+a++++tr l+++lap+gi vn+vaPG+++T++ ++
  EEA22318.1 103 DLFDRIYEINVKGPLFLAKAAVPHMP--EGSHIVFISTSLCHAGTIMppQLLYCSTKGAIEQFTRMLSRDLAPKGIVVNCVAPGPTATELFMR 193
                 ************************99..7789****9999988765522789*************************************9875 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.6   0.0   1.9e-13   4.9e-10       4     165 ..       9     169 ..       7     182 .. 0.83

  Alignments for each domain:
  == domain 1  score: 39.6 bits;  conditional E-value: 1.9e-13
                 EEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT--H CS
          KR   4 litGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklleemta 102
                 +itGG  g+G+++a++ ++ ga+ ++  s +   ++++++ +++l +   +v   +aD  + +  +++++e+ a++++i   i  Ag +  + le +t+
  EEA22318.1   9 VITGGSKGIGRAVAEQFVALGAKVVINYSSD---SAAADEVVQKLGR--DNVLSTKADAGSVAGTKQIVDEAVARFGKIDILIPNAGWMPMANLEAVTE 102
                 8****************************99...4556668888887..48999********************************************* PP

                 HHHHHHHTTTTHHHHHHHHHTTT....S--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHH CS
          KR 103 edleqvlapKvkGawnLhelled....esldffvlfSSiagllgsagqanYaaaNaflDalaeyrrs 165
                 + ++++++  vkG   L ++  +     s  +f+ +S + + + ++ q  Y ++   ++++ +  ++
  EEA22318.1 103 DLFDRIYEINVKGPLFLAKAAVPhmpeGSHIVFISTSLCHAGTIMPPQLLYCSTKGAIEQFTRMLSR 169
                 *****************99876645334444555555555666678888898888888888877655 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   6.9e-06     0.018       2     129 ..       9     139 ..       8     183 .. 0.70

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 6.9e-06
                      EEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH......-TTEEEE....E--TT-HHH.HHHHTT...T-SEEEE------HHHH CS
  Polysacc_synt_2   2 lvtGagGsiGselvrqilkkkpkkiillerdElklyeiekeleeelkkkklkveivpvigdvrdker.lekaleel.kvdvvfhaAAlKhVPlv 93 
                      ++tG++  iG+++ +q+++  +k +i +++d  + +e+ ++l    +++ l++   +  g+v+ +++ +++a+ ++ k+d+++  A    +  +
       EEA22318.1   9 VITGGSKGIGRAVAEQFVALGAKVVINYSSDSAAADEVVQKLG---RDNVLST--KADAGSVAGTKQiVDEAVARFgKIDILIPNAGWMPMANL 97 
                      69**************************************984...3333333..366899987655156677666479999999886655544 PP

                      HHSHH....HHHHHHHHHHHHHHHHHHHT..T-SEEEEEEEG CS
  Polysacc_synt_2  94 eenpl....eaiktNvlgtenvieaaiea..gvkkvvliStD 129
                      e  +        + Nv g   +++aa+ +  + +++v+iSt 
       EEA22318.1  98 EAVTEdlfdRIYEINVKGPLFLAKAAVPHmpEGSHIVFISTS 139
                      443331111345779999999999998762256789999985 PP

>> DUF1776  Fungal family of unknown function (DUF1776)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   4.2e-05      0.11      96     195 ..      84     181 ..      81     185 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 4.2e-05
     DUF1776  96 ilvPslsy.ptgpietiplsswaselnerllspiltlqallplltsrakqkakiivvnpsisssln.lpfhapEalvssalsalfevLkrelrphnidv 192
                 il+P+  + p+  +e ++++ +    + ++  p+ + +a +p++ +     ++i+++++s+ ++   +p + +   + +a+++++++L+r+l+p++i v
  EEA22318.1  84 ILIPNAGWmPMANLEAVTEDLFDRIYEINVKGPLFLAKAAVPHMPE----GSHIVFISTSLCHAGTiMPPQLLYCSTKGAIEQFTRMLSRDLAPKGIVV 178
                 89**********************9999*****************6....89*********9875414455556667789*****************99 PP

     DUF1776 193 tqi 195
                  ++
  EEA22318.1 179 NCV 181
                 877 PP

>> Phage_ABA_S  Phage ABA sandwich domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   9.2e-05      0.23      32      56 ..      33      57 ..      23      79 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 9.2e-05
  Phage_ABA_S 32 vfeysedisaAweVveklknegiei 56
                 v +ys+d +aA eVv+kl ++++  
   EEA22318.1 33 VINYSSDSAAADEVVQKLGRDNVLS 57
                 689***************9887765 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   0.00014      0.36       2     116 ..       9     139 ..       8     230 .. 0.65

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00014
                 EEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC........EEEE--TT-HH.HHHHHHHHH.T-SEEEE--S.---HHHHHHSH...HH CS
   Epimerase   2 lVtGatGfiGsalvkallekgyevigldrlssasntarledl........elveldltdrs.alerlfkee.qpdavihlAa.vggvaassedp...ad 86 
                 ++tG++  iG+a+++++ + g +v+   +  sa + +  ++l        +   + +   +  ++++++++ ++d+ i  A+     + ++ +     +
  EEA22318.1   9 VITGGSKGIGRAVAEQFVALGAKVVINYSSDSAAADEVVQKLgrdnvlstKADAGSVAGTKqIVDEAVARFgKIDILIPNAGwMPMANLEAVTEdlfDR 107
                 79*******************995555555466665555656888887774444444433336677777777788888887754333322222211134 PP

                 HHHHHTHHHHHHHHHHHHHTCT..EEEEEEEG CS
   Epimerase  87 fieknlqgtlnlleaarkagvk..rllflsSs 116
                 ++e+n++g l l++aa  + ++   ++f+s+s
  EEA22318.1 108 IYEINVKGPLFLAKAAVPHMPEgsHIVFISTS 139
                 56689999999999998886666688888885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (243 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       474  (0.0264376); expected 358.6 (0.02)
Passed bias filter:                      419  (0.02337); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 1768.62
//
Query:       EEA22319.1  [L=604]
Description: tripeptidyl peptidase A [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.6e-39  135.5   0.1    1.9e-38  132.0   0.0    2.1  2  Pro-kuma_activ  Pro-kumamolisin, activation domain
    1.5e-05   24.5   1.5    2.2e-05   23.9   0.0    1.8  2  Peptidase_S8    Subtilase family


Domain annotation for each model (and alignments):
>> Pro-kuma_activ  Pro-kumamolisin, activation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.0   0.0   2.1e-42   1.9e-38       1     142 []      37     174 ..      37     174 .. 0.99
   2 ?    1.2   0.0     0.047   4.2e+02     105     131 ..     183     225 ..     179     287 .. 0.76

  Alignments for each domain:
  == domain 1  score: 132.0 bits;  conditional E-value: 2.1e-42
  Pro-kuma_activ   1 tgwtkrgraasstllpvrigLkqnnlekledflmdvsdpkspnygkhltaeevaelfapseeaidaVrnwLessgiaasrhsdtkgwiafsatva 95 
                     +gw k+++ a +t+++++++L+ +n+e+l+++l+ vs+p+s+ yg++l+++++a++++ps++++daV++wL+++gi+  +  ++++ i+f +tv+
      EEA22319.1  37 PGWDKVNTPAGHTNIQLSVALTLQNIEQLQSHLQSVSTPGSSGYGQYLDSDDIAAQYGPSDASVDAVTKWLKEAGITEIH--NNGQSINFATTVS 129
                     58******************************************************************************..************* PP

  Pro-kuma_activ  96 qverllktsfeaYshkkgssslarcdeyslPealknyvdyihptdnf 142
                     ++++ll+++f++Ys  +g+ + +r+  ys+P +l+  +d++ pt+ f
      EEA22319.1 130 KANKLLGADFHYYS--DGGATKLRTLAYSVPSDLQAAIDLVSPTTYF 174
                     **************..8***************************976 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.047
  Pro-kuma_activ 105 feaYshk.......kgss.....slarcdeyslPealk......n 131
                     +++Ys+k       +          a c++ ++P++lk      n
      EEA22319.1 183 IQTYSNKrastttkS--GsssvaVAASCQTSITPACLKqmynvgN 225
                     566776544444431..0334446778999*******95555553 PP

>> Peptidase_S8  Subtilase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   1.0      0.18   1.6e+03     230     264 ..     180     220 ..     125     233 .. 0.58
   2 !   23.9   0.0   2.4e-09   2.2e-05     120     264 ..     339     520 ..     316     529 .. 0.75

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.18
                   CCCHHHTTTHH..EEEE-SHH....HCHHHHHHHHHHHHHH CS
                   xxxxxxxxxxx..xxxxxxxx....xxxxxxxxxxxxxxxx RF
  Peptidase_S8 230 rqsnnsaglss..yqsmsGTS....mAsPnaagaaAlllsa 264
                    +s ++++ +   ++++sG+S    +As   +   A+l++ 
    EEA22319.1 180 SRSIQTYSNKRasTTTKSGSSsvavAASCQTSITPACLKQM 220
                   22222222222446677776622222333333334555554 PP

  == domain 2  score: 23.9 bits;  conditional E-value: 2.4e-09
                   CT-S...EEEE-EESCETTCHHCHHHHHH..HHHHHH.CCT-EEEEE--SS-T-HH......EEE-TTCEECTTTSTTCEEEEEES........... CS
                   xxxx...xxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxxx........... RF
  Peptidase_S8 120 dkvd...vinmslgestslpktgrsieal..ainravnkkgvlvviSaGNngktgs......slqagspvgtpstsknvitvgayt........... 194
                   +++d   vi++s+g +++++ +++    +  +i  +   +g+ v  S+G  g  +       + ++  +  +p+t+  +++vg+++           
    EEA22319.1 339 KNADlpqVISNSYG-DDEQSVPYKYAVRAcnLIGLTG-LRGITVLESSGDLGVGAGclsndgKNKTQFDAIFPATCPYITAVGGTQavtpeiawtas 433
                   3444444*******.5555555443322345444444.56************44446666333344444445************************* PP

                   .........................TTSSB-TT--B-TT.......-EEEE-S-CCCCCCCCCHHHTTTHHEEEE-SHHHCHHHHHHHHHHHHHH CS
                   .........................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8 195 .........................tegkiapfSsrGpssdgklkpdivapGgnivstwsrqsnnsaglssyqsmsGTSmAsPnaagaaAlllsa 264
                                            +++   ++S++  +++g+  pd++a      ++++  +  +     +q   GTS+AsP+ ag++All +a
    EEA22319.1 434 sggfsyyfprpwyqrkaietylgllDDSTKQYYSQYT-NFEGRGFPDVAAHSLL--PDYQVVGGGE-----LQRSGGTSAASPVFAGIIALLNDA 520
                   ************************7555555666555.5789999****99876..8888888333.....899*****************9874 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (604 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       478  (0.0266607); expected 358.6 (0.02)
Passed bias filter:                      361  (0.020135); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.24s 00:00:00.84 Elapsed: 00:00:00.43
# Mc/sec: 4263.69
//
Query:       EEA22320.1  [L=310]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.4e-38  130.2   0.1    9.3e-38  129.6   0.1    1.2  1  adh_short        short chain dehydrogenase
    4.8e-30  104.8   0.1    9.3e-30  103.9   0.1    1.5  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    6.9e-15   55.4   0.2    9.8e-15   54.9   0.2    1.2  1  KR               KR domain
    5.1e-08   32.4   0.1    9.4e-08   31.5   0.0    1.4  2  Polysacc_synt_2  Polysaccharide biosynthesis protein
     0.0035   16.8   0.2      0.012   15.0   0.2    2.0  1  Epimerase        NAD dependent epimerase/dehydratase family
  ------ inclusion threshold ------
      0.013   14.8   0.0      0.019   14.2   0.0    1.2  1  Pyr_redox_2      Pyridine nucleotide-disulphide oxidoreductas
      0.035   14.7   0.1       0.07   13.7   0.1    1.6  1  Pyr_redox        Pyridine nucleotide-disulphide oxidoreductas
      0.049   12.6   0.1      0.075   12.0   0.1    1.2  1  3Beta_HSD        3-beta hydroxysteroid dehydrogenase/isomeras
       0.27   10.6   1.2        2.1    7.7   0.3    2.2  2  ThiF             ThiF family


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  129.6   0.1   4.7e-41   9.3e-38       1     190 [.      32     227 ..      32     229 .. 0.94

  Alignments for each domain:
  == domain 1  score: 129.6 bits;  conditional E-value: 4.7e-41
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHT..TSEEEEEE-TTTSHHHHHHHHHHHH..HHHSSESEEEE---S.S--SSG CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvv.vdrseekleevakelkee..gakalaiqvDvtdreevealvekav..kklgkldvLvnNAGi.tgsgpf 93 
                 k+v+vtG++sGIG +ia+ +ak+Ga+ ++ ++r+e++l  +++++++     +++++++Dvt++++v++++ek v  +k gk+d+L+ NA++    +p+
  EEA22320.1  32 KTVVVTGGGSGIGAEIARYFAKAGASRIAlLGRREQPLLDTKASIEQInaDVDVFVVSTDVTKKDQVDTAFEKFVggDKPGKIDILISNAAVvGPLEPI 130
                 79***********************99988****************9987888********************9833566************9999*** PP

                 GGCSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-.TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHH CS
   adh_short  94 selseeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpv.agvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakel 190
                 s+++ e + + i++Nl+g + +++a+l++ + ++ + ++ + S a+++ + a +++Ys +K av  l +sl  e+++++ r+  ++PG++dTdm++++
  EEA22320.1 131 SSVEGESFLDAIHTNLQGSLYVAQAFLRYAI-ANDAVVIDINSSAAHMDFgAALVSYSVAKLAVYRLWDSLGFEFEKQRMRIYHIQPGVIDTDMNRSV 227
                 *****************************66.999***********8876367899**************************************9875 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.9   0.1   4.7e-33   9.3e-30       4     189 ..      41     234 ..      36     265 .. 0.88

  Alignments for each domain:
  == domain 1  score: 103.9 bits;  conditional E-value: 4.7e-33
                   TSHHHHHHHHHHHTT-E.EEEEESSGGHHHHHHHHHHHTTSEE....EE--TTSHHHHHHHHHHHH..HHHSSEEEEEE-----EGCSS-GGGH-HH CS
  adh_short_C2   4 sgIGraiAkalaeeGae.vvltdlneeakkrveelaeelgaev....lecDVtdeeqvealveevv..ekfgklDilvnnagiapklkgpfletsre 93 
                   sgIG++iA+ +a++Ga+ ++l  ++e+   ++++  e+++a+v    + +DVt+++qv++++e+ v  +k gk+Dil+ na+++ +  +p+ +++ e
    EEA22320.1  41 SGIGAEIARYFAKAGASrIALLGRREQPLLDTKASIEQINADVdvfvVSTDVTKKDQVDTAFEKFVggDKPGKIDILISNAAVVGP-LEPISSVEGE 136
                   8***************7588888888877788888888887744467*****************9833456***************.9********* PP

                   HHHHHHHHHTHHHHHHHHHHHH.HCTSCCEEEEEEEGGGTSBSTTTT.HHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTTHHHH CS
  adh_short_C2  94 efdraldvnlyslfllakaalp.lmkeggsivnlssvgaervvpnyn.aygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikgfdel 188
                   +f +a+++nl++ +++a+a+l+ ++++ + ++ + s +a++ +      y++aK a+  l  +l  e+ ++++R+  + pg+i+T++++++ g  ++
    EEA22320.1 137 SFLDAIHTNLQGSLYVAQAFLRyAIANDAVVIDINSSAAHMDFGAALvSYSVAKLAVYRLWDSLGFEFEKQRMRIYHIQPGVIDTDMNRSVGGIAAM 233
                   **********************888888******99999999777766*****************************************99987666 PP

                   H CS
  adh_short_C2 189 l 189
                    
    EEA22320.1 234 G 234
                   4 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.9   0.2   4.9e-18   9.8e-15       2     150 ..      33     187 ..      32     196 .. 0.84

  Alignments for each domain:
  == domain 1  score: 54.9 bits;  conditional E-value: 4.9e-18
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHS..S---EEEE------.---T CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaee..ppikGvihaAgvlr.dkll 97 
                 t+++tGG  g+G e+ar  a+ ga++++ll+R++++  d ka i++++a +++v vv+ Dv++kd+v +++e++   +  ++i   i  A v+   +++
  EEA22320.1  33 TVVVTGGGSGIGAEIARYFAKAGASRIALLGRREQPLLDTKASIEQINA-DVDVFVVSTDVTKKDQVDTAFEKFVGGDkpGKIDILISNAAVVGpLEPI 130
                 689*******************************************998.9**********************987665789999887666665389** PP

                 TT--HHHHHHHHTTTTHHHHHHHHHTTT..S--SEEEE..EEEHHHHH--TT-HHHH CS
          KR  98 eemtaedleqvlapKvkGawnLhelled..esldffvl..fSSiagllgsagqanYa 150
                 ++++ e++  +++  ++G+  + +++ +     d +v+   SS+a +   a  ++Y+
  EEA22320.1 131 SSVEGESFLDAIHTNLQGSLYVAQAFLRyaIANDAVVIdiNSSAAHMDFGAALVSYS 187
                 *************************98866555655532256666554455555555 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.5   0.0   4.7e-11   9.4e-08       1     121 [.      34     162 ..      34     174 .. 0.83
   2 ?   -3.6   0.0       2.4   4.8e+03     250     270 ..     277     297 ..     271     300 .. 0.75

  Alignments for each domain:
  == domain 1  score: 31.5 bits;  conditional E-value: 4.7e-11
                      EEEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH......-TTEEEE....E--TT-HHHHHHHTT.........T-SEEEE---. CS
  Polysacc_synt_2   1 vlvtGagGsiGselvrqilkkkpkkiillerdElklyeiekeleeelkkkklkveivpvigdvrdkerlekaleel.......kvdvvfhaAA. 86 
                      v+vtG+g  iG e+ r ++k  +++i ll r E+ l + + ++e+  ++  +  ++++v +dv++k+++++a+e++       k+d+++  AA 
       EEA22320.1  34 VVVTGGGSGIGAEIARYFAKAGASRIALLGRREQPLLDTKASIEQINAD--V--DVFVVSTDVTKKDQVDTAFEKFvggdkpgKIDILISNAAv 123
                      79************************************99998544333..4..5568899*************97666666689999999993 PP

                      ...---HHHHH.HSHHHHHHHHHHHHHHHHHHHHHTT-S CS
  Polysacc_synt_2  87 ...lKhVPlve.enpleaiktNvlgtenvieaaieagvk 121
                         l  +  ve e  l+ai+tN  g+  v++a +++ + 
       EEA22320.1 124 vgpLEPISSVEgESFLDAIHTNLQGSLYVAQAFLRYAIA 162
                      33335688888346789**************99888775 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 2.4
                      ....SSSS-EEE----TT--S CS
  Polysacc_synt_2 250 eekkeedieikitGlRpGEkl 270
                      e ++ ++ +i+++G   GEk 
       EEA22320.1 277 EIEEGQEFNIQVVGWPFGEKK 297
                      445567899999999999995 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.2   6.2e-06     0.012       1     108 [.      34     162 ..      34     207 .. 0.71

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 6.2e-06
                 EEEETTTSHHHHHHHHHHHHCTSE.EEEEES-STTTTCHHCHHC...........EEEE--TT-HHHHHHHHHH.....H..T-SEEEE--S---H... CS
   Epimerase   1 ilVtGatGfiGsalvkallekgye.vigldrlssasntarledl...........elveldltdrsalerlfke.....e..qpdavihlAavggv... 77 
                 ++VtG+   iG+ ++++++++g   +  l r+ ++     +  +            +v  d+t++++++ +f++     +  ++d+ i  Aav g+   
  EEA22320.1  34 VVVTGGGSGIGAEIARYFAKAGASrIALLGRR-EQPLLDTK--AsieqinadvdvFVVSTDVTKKDQVDTAFEKfvggdKpgKIDILISNAAVVGPlep 129
                 68********************5535555555.33322222..1346669999*999*********888888753333212468999999996555111 PP

                 ..HHHHHSHHHHHHHHTHHHHHHHHHHHHHTCT CS
   Epimerase  78 ..aassedpadfieknlqgtlnlleaarkagvk 108
                   +++ e+  d i++nlqg+l +++a  ++ + 
  EEA22320.1 130 isSVEGESFLDAIHTNLQGSLYVAQAFLRYAIA 162
                 113344556788999999999999999988765 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   9.7e-06     0.019     138     184 ..      27      75 ..       9     107 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 9.7e-06
                  CSS-TSEEEEES-SH.HHHHHHHHHHHHT-E.EEEEESSSSSSTTS-HH CS
                  xxxxxxxxxxxxxxx.xxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 138 lkllpkrivvvGgGy.iGvElAaalaklgke.vtlveardrllraldke 184
                  l  + k +vv GgG  iG E+A ++ak+g+  + l+ +r+++l  ++ +
   EEA22320.1  27 LSAKGKTVVVTGGGSgIGAEIARYFAKAGASrIALLGRREQPLLDTKAS 75 
                  3344488999998855************88669******9999434444 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.1   3.5e-05      0.07       3      43 ..      35      75 ..      33      97 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 3.5e-05
                EEE.CSSHHHHHHHHHHHHTT.SEEEEEESSSSSSTTSSHHHH CS
   Pyr_redox  3 vvv.GgGyiglElAgalaelg.kkVtvversdkllrllDeeas 43
                vv  Gg+ ig E A ++a+ g +++ ++ r++++l  lD +as
  EEA22320.1 35 VVTgGGSGIGAEIARYFAKAGaSRIALLGRREQPL--LDTKAS 75
                55515668***********996799**********..877664 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.1   3.7e-05     0.075       1      65 [.      35     103 ..      35     106 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 3.7e-05
   3Beta_HSD   1 vvtGgaGFlGralvkeLvrleelkevrvlDlrespelleelskvnvkk......viegDvtdkdkleeale 65 
                 vvtGg+  +G+++ + + +++ +  +  l  re+p l ++  +++ ++      v+ +Dvt+kd+++ a e
  EEA22320.1  35 VVTGGGSGIGAEIARYFAKAG-ASRIALLGRREQPLL-DTKASIEQINadvdvfVVSTDVTKKDQVDTAFE 103
                 89*******************.699999998888766.444444433336688999************987 PP

>> ThiF  ThiF family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.3     0.001       2.1      19      47 ..      32      61 ..      23      63 .. 0.85
   2 ?    0.9   0.0      0.12   2.4e+02      78     110 ..      73     105 ..      72     121 .. 0.81

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.001
                SEEEEE--S.HHHHHHHHHHHHHTTTEEEE CS
                xxxxxxxxx.xxxxxxxxxxxxxxxxxxxx RF
        ThiF 19 skvllvGaG.glGsellknLalsGvgkltl 47
                ++v++ G G g+G e+++++a++G +++ l
  EEA22320.1 32 KTVVVTGGGsGIGAEIARYFAKAGASRIAL 61
                67788888779***************9987 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.12
                 HHHHHHT-TTSEEEEEES-CCG.CCS-HHHHTT- CS
                 xxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxx RF
        ThiF  78 aealqeinpdveveavteritd.etvleellesv 110
                 ++++++in dv+v  v  ++t+ ++ ++  +e++
  EEA22320.1  73 KASIEQINADVDVFVVSTDVTKkDQ-VDTAFEKF 105
                 67899****************9544.56777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (310 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       495  (0.0276089); expected 358.6 (0.02)
Passed bias filter:                      431  (0.0240393); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.67u 0.36s 00:00:01.03 Elapsed: 00:00:00.58
# Mc/sec: 1619.18
//
Query:       EEA22321.1  [L=467]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (467 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.65u 0.37s 00:00:01.02 Elapsed: 00:00:00.56
# Mc/sec: 2518.63
//
Query:       EEA22322.1  [L=417]
Description: Acidic endochitinase precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.8e-23   82.1   1.1      2e-22   80.3   1.1    1.6  1  Glyco_hydro_18  Glycosyl hydrolases family 18
    3.9e-12   45.9   7.8    3.9e-12   45.9   7.8    2.4  3  CBM_1           Fungal cellulose binding domain
  ------ inclusion threshold ------
       0.74   10.2   2.9        5.5    7.4   2.9    2.3  1  GHMP_kinases_C  GHMP kinases C terminal


Domain annotation for each model (and alignments):
>> Glyco_hydro_18  Glycosyl hydrolases family 18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.3   1.1   3.4e-26     2e-22       2     310 ..      34     317 ..      33     320 .. 0.73

  Alignments for each domain:
  == domain 1  score: 80.3 bits;  conditional E-value: 3.4e-26
                     EEEEEEGGGGGSS.G..CSH.....TTTESEEEEEEEEEEETTTEEEESS.TTHH..........HHHHHHHHHH.HHTSTT-EEEEEEEETTTT CS
                     xxxxxxxxxxxxx.x..xxx.....xxxxxxxxxxxxxxxxxxxxxxxxx.xxxx..........xxxxxxxxxx.xxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18   2 vvgYysswesygn.n..ylp.....saklthiiyaFakidgengkvvvsd.wedl..........gnfeqlkklk.kkknpgvkvllsiGGwtds 76 
                     +v+Y+++++     +          s+++++i++aF+   g ng  v +   +++          +  +++++   + +n+gvk+lls+GG+++ 
      EEA22322.1  34 TVVYWGQNGGGVIeAtdL-AtycsiSSGIDIIVLAFLYQYG-NGVTVPGGgFGQTcyilagsgtaQSCSAVASAItTCQNNGVKILLSLGGASG- 125
                     799**9998775433331.234447************8888.544444444444456666666665666666666688888***********99. PP

                     THHHHHHTSHHHHHHHHHHHHHHH.........HHCT...-SEEEEEES-TTTSTCHHHHHHHHHHHHHHHHH.HHHHHTSTTCEEEEEEESSHH CS
                     xxxxxxxxxxxxxxxxxxxxxxxx.........xxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18  77 sgfslaastdasrkkfadsvvsll.........rkyg...fDGiDidweypggnpedkenytallkelreald.kakategkkllLsaavpasas 158
                      g+sl+  +++++k+  d++++ +         r++g   + G D+d+e  +g     + y+ l+++lr+ +  +      +k+++s a++++ +
      EEA22322.1 126 -GYSLT--SQTEAKAIGDYLWQAYgnpssitvpRPFGnaiVNGWDFDIENASG----SSYYPYLIAALRSNFAsDS----ASKYYISGAPQCPIP 209
                     .***99..4589************9999999999999************6555....99***********998443....589************ PP

                     H.HHHHCHHHHHHHHTSEEEEETTTSSSTTSS...BE--SS-SSB....TCSSHHHHHHHHHHTT--GGGEEEEEESEEEEEEESSSSSSTSTTT CS
                     x.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18 159 d.lskgydlpkiakylDyvnvmtYDfhgswdn...vtghhaplyd....aslnvdeavkeylkagvpakklvlGvpfygrawalvsgadntkeeg 245
                     +  + +     ++++ D++++++Y+ ++  +     ++  apl++    + +++++++          +kl++Gvp+++ a+++++        g
      EEA22322.1 210 EpNMGS---MIANSTFDMLFIQFYNNNNYTNPcalGINGDAPLNYlewvSFISTSKSL---------DAKLFIGVPASTLAANGGES-------G 285
                     *54333...3335777********9998444465566667777553221123333322.........67*********999887654.......3 PP

                     EEEHHHHHHHHTEEEEEEEEETTTTEEEEEETTEEEEE-SHHHHHHHH.HHHHHTTESEEEEETGG CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18 246 vlsykelkellkkakakrkydskakapyvydgeefvsyDdpksikaka.dyvkakglgGvmiWsld 310
                     ++                         y+          +p++++  + d   + ++gGvm+Ws++
      EEA22322.1 286 SI------------------------YYA----------TPEQLNIIVgDTRGNTSFGGVMMWSAG 317
                     22........................333..........777777777777777778888888776 PP

>> CBM_1  Fungal cellulose binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -6.4   3.2         3   1.8e+04       2       7 ..      38      43 ..      38      44 .. 0.87
   2 ?   -4.2   0.1       2.9   1.7e+04      14      17 ..     107     110 ..     104     111 .. 0.67
   3 !   45.9   7.8   6.6e-16   3.9e-12       1      29 []     383     411 ..     383     411 .. 0.98

  Alignments for each domain:
  == domain 1  score: -6.4 bits;  conditional E-value: 3
       CBM_1  2 wgQCGG 7 
                wgQ GG
  EEA22322.1 38 WGQNGG 43
                9**888 PP

  == domain 2  score: -4.2 bits;  conditional E-value: 2.9
       CBM_1  14 TtCv 17 
                 TtC+
  EEA22322.1 107 TTCQ 110
                 6665 PP

  == domain 3  score: 45.9 bits;  conditional E-value: 6.6e-16
       CBM_1   1 lwgQCGGigWtGpTtCvsgatCtyqNeyY 29 
                 +wgQCGGig+tG+T+C+sg  C+y+++y+
  EEA22322.1 383 EWGQCGGIGYTGSTVCASGLICVYVSPYW 411
                 6***************************9 PP

>> GHMP_kinases_C  GHMP kinases C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   2.9   0.00091       5.5      39      66 ..      65      91 ..      48     146 .. 0.88

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.00091
  GHMP_kinases_C 39 llealselGalgaklsGaGgGptvfalf 66
                    +l +l+++G  g+ ++G G+G t+++l+
      EEA22322.1 65 VLAFLYQYG-NGVTVPGGGFGQTCYILA 91
                    6889999**.9***************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (417 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       492  (0.0274416); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 2641.54
//
Query:       EEA22323.1  [L=659]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.6e-10   37.9   0.1    1.7e-09   37.1   0.1    1.5  1  Fungal_trans  Fungal specific transcription factor domain
  ------ inclusion threshold ------
      0.083   11.2   0.0       0.12   10.7   0.0    1.1  1  CDC45         CDC45-like protein


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.1   0.1   1.9e-13   1.7e-09      99     200 ..     288     383 ..     279     489 .. 0.90

  Alignments for each domain:
  == domain 1  score: 37.1 bits;  conditional E-value: 1.9e-13
  Fungal_trans  99 llelyektssd.ralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddlwe 194
                   +++l ++ ++d  +  ++++g   +l++slg+h++++++       l+++ +e r+Rl ++a+++Dk +a+ lGrpp ++   i++ LP d   ++e
    EEA22323.1 288 HASLLSFVYGDhDYRPWKILGDLSTLVYSLGFHQRQNNET------LPFFLIEHRKRLLLGAYSIDKELATFLGRPPRISWRHIDVDLPLDIT-YNE 377
                   556666777776788899**********************......*******************************77**********9987.777 PP

  Fungal_trans 195 sddase 200
                    + + e
    EEA22323.1 378 LLAEPE 383
                   666555 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   1.3e-05      0.12     289     338 ..     106     155 ..      67     167 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 1.3e-05
       CDC45 289 ktekietkarspddtsirlseelrllLlRhWsLydSmlhssYvaskLklW 338
                  +++ + +++  dd  i++  el l+L++  +Ly+ m  s++  +  +++
  EEA22323.1 106 FSKSLKRSQNLVDDADIQVGAELLLFLYQDFTLYERMSISKFCHCEGHVF 155
                 4445566677899*****************************99876665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (659 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       551  (0.0307323); expected 358.6 (0.02)
Passed bias filter:                      507  (0.0282782); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.42
# Mc/sec: 4757.17
//
Query:       EEA22324.1  [L=67]
Description: hypothetical protein PMAA_061030 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (67 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       379  (0.0211389); expected 358.6 (0.02)
Passed bias filter:                      248  (0.0138323); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.37u 0.24s 00:00:00.61 Elapsed: 00:00:00.40
# Mc/sec: 501.56
//
Query:       EEA22325.1  [L=575]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.5e-35  121.6  83.8    2.3e-34  118.9  62.9    3.1  2  MFS_1            Major Facilitator Superfamily
    1.3e-21   76.7  30.7    1.8e-21   76.2  30.7    1.1  1  TRI12            Fungal trichothecene efflux pump (TRI12)
    7.2e-13   48.2   3.5    7.2e-13   48.2   3.5    2.8  3  Sugar_tr         Sugar (and other) transporter
  ------ inclusion threshold ------
      0.022   15.0   1.6      0.022   15.0   1.6    3.3  2  DUF3522          Protein of unknown function (DUF3522)
       0.76    9.6   3.6        7.5    6.4   0.0    2.7  2  Gly-zipper_YMGG  YMGG-like Gly-zipper
        4.4    5.5  24.3      0.038   12.3   4.5    4.0  4  OATP             Organic Anion Transporter Polypeptide (OATP)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.9  62.9   7.6e-38   2.3e-34       1     352 [.      70     469 ..      70     470 .. 0.92
   2 !   17.0  12.8   7.4e-07    0.0022      62     232 ..     390     560 ..     387     571 .. 0.73

  Alignments for each domain:
  == domain 1  score: 118.9 bits;  conditional E-value: 7.6e-38
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlga 99 
                 l+l++++++l++++l++a+p  +++dl+ +  ++ ++   + l+ ++ ++++ ++sd +Gr+  l +g++lf +g++++++a+s+ +l+++rv+qGlg+
  EEA22325.1  70 LMLVILIVSLDATALSVAIP-VITSDLNGTSLSAFWAGISFVLAVVIVQPIYTSVSDVLGRKVALYTGFILFTIGSIIFAVAHSMSILILGRVIQGLGG 167
                 578999**************.9*****************************************************66666669999************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 g+l  +  ++iad+++ +er++++gl+s+ +++G++lgp+lg+++++++ Wr++ +i+ ++ ++++ l++l+l  +p e++  s    +          
  EEA22325.1 168 GGLDVLNEIIIADITTLKERPLYLGLMSVPMAIGTALGPILGAVFSENVTWRWIGWINLPIIAVSAPLAVLFLHLKPIEKSIWSRLASLdwiglalfai 266
                 *******************************************************************999***99999988888888888********* PP

       MFS_1 189 ........................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllag 247
                                                         + +  +p++p +++++++  +   l+++++ ++++++ll+++pl++ +v+  ++l +a 
  EEA22325.1 267 gitifalplswggalypwsswrtivplvigiailavfavyEARPAQPVFP-YRIFRSRTAVV-TLLGSFIHGMVLYTLLFYMPLFFESVFLETSLGSAI 363
                 *******************9999999999999999999988888899999.*******9775.99999999**************99999888566777 PP

       MFS_1 248 lllallalvgailallagrlsdr.lgrrrrlllallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdlapp.eeagtasglfnta 344
                  +l+ll++v+a+++ la++++      r+ ++l+ + l++++ ++a++ + ss ++ + + v++G+g+g  f+ l   ++ +ap+ e +g a+g+  ++
  EEA22325.1 364 SMLPLLCMVTAFSG-LAAWVVEYvRHYRWEIWLGWVMLTAGTGLFAIWDAQSSLAIKASFQVIAGIGMGSLFTVLPMPMQASAPTaEDQGLAVGVLVSF 461
                 77899999998884.7777776633448899999999999999999999998888888899999999999999999999999987699*********** PP

       MFS_1 345 gslggalg 352
                 + +g+++g
  EEA22325.1 462 RLFGALVG 469
                 ****9998 PP

  == domain 2  score: 17.0 bits;  conditional E-value: 7.4e-07
       MFS_1  62 rrvlllglllfalg.lllllf.asslw.lllvlrvlqGlgagalfpagaaliadwfpk.eergraigllsagfslGailgpllgg.llasslgWravfy 155
                 r+ ++lg +++ +g +l++++ a+s+  + + + v++G+g+g+lf++    + + +p  e++g+a+g+l ++  +Ga++g ++g+ +++s +g+  + +
  EEA22325.1 390 RWEIWLGWVMLTAGtGLFAIWdAQSSLaIKASFQVIAGIGMGSLFTVLPMPMQASAPTaEDQGLAVGVLVSFRLFGALVGLAIGStAFSSTFGYGIAGL 488
                 665777888888885666667655555599***********999998888888888888*********************8888846668888755555 PP

       MFS_1 156 ilaivsllafvlfllllpeepperkrkspkeeekgtgpaplvp....awkallkdpvl..willialllfffgfsglltllpl 232
                    +  ++a       l +++ + +  ++ ++ +        p    a++++ +d     w++l++++ f+f +s+l++ l+l
  EEA22325.1 489 GSNLPEAVA------ILKDPNQAIGFIPHLRQFQNLS-----PeelhAIQSVYRDSMQtiWYILTGFCAFGFLTSLLTASLTL 560
                 555555555......4577777777777777743333.....22344588899888444588888888888888877777766 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.2  30.7     6e-25   1.8e-21      47     458 ..      66     469 ..      52     498 .. 0.76

  Alignments for each domain:
  == domain 1  score: 76.2 bits;  conditional E-value: 6e-25
       TRI12  47 aafslnvvatyfvlqasa..salpnilqdvgqsensslfstlwttgqavsil..vmgrltdrfgrrpfvilthilglvgaivgctatkfntllaamtll 141
                 a +sl +v   + l+a+a   a+p i  d+  +  s++++ +     av i+  +   ++d +gr+  +    il  +g+i+ + a  +  l+    + 
  EEA22325.1  66 AVLSLMLVILIVSLDATAlsVAIPVITSDLNGTSLSAFWAGISF-VLAVVIVqpIYTSVSDVLGRKVALYTGFILFTIGSIIFAVAHSMSILILGRVIQ 163
                 55666666666666665532466777777765555555544433.34444443367899**************************************** PP

       TRI12 142 gvaagpaga.splfvgelmsnktkflgllivsipvvvtsglspylgqrlaiqgswrwifyiyiitsaiavllivvwyyppsfaqlhgkkvrkreelakl 239
                 g+  g       +++ ++ + k + l l ++s+p+ + ++l+p lg  ++ + +wrwi +i + + a++  l v++ +            +    la l
  EEA22325.1 164 GLGGGGLDVlNEIIIADITTLKERPLYLGLMSVPMAIGTALGPILGAVFSENVTWRWIGWINLPIIAVSAPLAVLFLHLK------PIEKSIWSRLASL 256
                 **988765427899*********99999999****99999*********************9988888888888876533......333445678**** PP

       TRI12 240 dwigiilvivgvslfllgvswggkpnspwnsakviglissglgslvvfalyevygkpvrpivppalfkdtrgfvcillissimgamnlslviiypqqvv 338
                 dwig+ l ++g+++f l +swgg    pw s + i  +  g+  l vfa+ye   +p +p+ p  +f+  r  v+ ll s i g +  +l    p    
  EEA22325.1 257 DWIGLALFAIGITIFALPLSWGGAL-YPWSSWRTIVPLVIGIAILAVFAVYE--ARPAQPVFPYRIFRS-RTAVVTLLGSFIHGMVLYTLLFYMPLFFE 351
                 ***********************75.7*********9***************..59***********95.77788888999999888888888887776 PP

       TRI12 339 nif.gsslknw.eetawmsatasfgtgagvvvlgslfhlvrhirwqilvgalwltaflgamssvnrdnknaaials..vlsgfvvawaqd.itmllvqf 432
                  +f  +sl         ++  ++f   a       ++  vrh rw+i +g + lta  g ++  +  +   ai  s  v++g+ ++     + m +   
  EEA22325.1 352 SVFlETSLGSAiSMLPLLCMVTAFSGLA-----AWVVEYVRHYRWEIWLGWVMLTAGTGLFAIWD-AQSSLAIKASfqVIAGIGMGSLFTvLPMPMQAS 444
                 6663344443202233333333443333.....346689*****************999876554.455556665511567776665444145667778 PP

       TRI12 433 ittdedlgvafavvaaarpfagsift 458
                   t ed g+a+ v+ + r f  +++ 
  EEA22325.1 445 APTAEDQGLAVGVLVSFRLFG-ALVG 469
                 89***********99988764.3333 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.2   3.5   2.4e-16   7.2e-13      54     178 ..     108     226 ..      11     244 .. 0.84
   2 ?   -2.4   0.1      0.55   1.6e+03     324     363 ..     265     306 ..     258     317 .. 0.50
   3 !    7.0   9.2   0.00077       2.3      51     158 ..     362     473 ..     324     490 .. 0.80

  Alignments for each domain:
  == domain 1  score: 48.2 bits;  conditional E-value: 2.4e-16
                 THHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHH CS
    Sugar_tr  54 iflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGil 152
                 +f++  +i + +   ++d++GRk +l ++ +lf ig+++ a+a+   s+ +li+gRv+ G+g G+  vl  + i+ i++ k R    +l  + +++G  
  EEA22325.1 108 SFVLAVVIVQPIYTSVSDVLGRKVALYTGFILFTIGSIIFAVAH---SMSILILGRVIQGLGGGGLDVLNEIIIADITTLKERPLYLGLMSVPMAIGTA 203
                 45555555666677799***************************...**************************************************** PP

                 HHHHHHHHHHTSS-TTHHHHHHHCCH CS
    Sugar_tr 153 vaaifglglnktsnadgwrillglql 178
                 ++ i+g++++++     wr+  +++l
  EEA22325.1 204 LGPILGAVFSENVT---WRWIGWINL 226
                 **********9999...665555444 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.55
                 HHHHHHHHHHHH....HHHHTTSS...CHHHHHHHHHHHHHH CS
    Sugar_tr 324 aagmaicfvilg..ivalllvakskaasivaivfialfialf 363
                 a+g +i+++ l+  ++ +++++  +    v+ ++i+ ++a++
  EEA22325.1 265 AIGITIFALPLSwgGALYPWSSWRTIVPLVIGIAILAVFAVY 306
                 344444444454333444444444444444444555555555 PP

  == domain 3  score: 7.0 bits;  conditional E-value: 0.00077
                 HHHTHHHHHHHHHH..HHHHHHHHT.THHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCH.HHHHHHHHH CS
    Sugar_tr  51 ivsiflvGaiiGsl..fagllgdrf.GRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklR.galvslyql 145
                   s++ + ++++++  +a ++++++  +++ +  + v++ +g+ l a+ ++++s+ + +  +v++Gig+G   ++ Pm ++  Ap++   g  v++  +
  EEA22325.1 362 AISMLPLLCMVTAFsgLAAWVVEYVrHYRWEIWLGWVMLTAGTGLFAIWDAQSSLAIKASFQVIAGIGMGSLFTVLPMPMQASAPTAEDqGLAVGVLVS 460
                 45555566666655222344444432789*******************************************************998765888999999 PP

                 HHHHHHHHHHHHH CS
    Sugar_tr 146 aitfGilvaaifg 158
                 +  fG lv+  +g
  EEA22325.1 461 FRLFGALVGLAIG 473
                 9999999987766 PP

>> DUF3522  Protein of unknown function (DUF3522)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   2.3       1.2   3.6e+03      92     121 ..      65      94 ..      58     154 .. 0.50
   2 ?   15.0   1.6   7.4e-06     0.022     105     171 ..     280     341 ..     229     359 .. 0.78

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.2
     DUF3522  92 lhylglllvailqekdrwslantiipilvg 121
                 l +l l+lv++++ +d++ l++ i +i + 
  EEA22325.1  65 LAVLSLMLVILIVSLDATALSVAIPVITSD 94 
                 555556666666666666555544444433 PP

  == domain 2  score: 15.0 bits;  conditional E-value: 7.4e-06
     DUF3522 105 ekdrwslantiipilvgllillvswliecvkkrklypsllrrrlkrlnlqqllpgllllalAlfllg 171
                 ++ +ws++ ti+p+++g++il+v+ ++e +  + ++p ++      + +  ++  l +++ +++l++
  EEA22325.1 280 ALYPWSSWRTIVPLVIGIAILAVFAVYEARPAQPVFPYRI-----FRSRTAVVTLLGSFIHGMVLYT 341
                 6679*************************99999999822.....2222333333344444444443 PP

>> Gly-zipper_YMGG  YMGG-like Gly-zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.0    0.0025       7.5       8      22 ..     199     213 ..     198     219 .. 0.87
   2 ?    1.9   1.9     0.065   1.9e+02      14      22 ..     465     473 ..     452     489 .. 0.74

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0025
                      XXXXXXXXXXXXXXX CS
  Gly-zipper_YMGG   8 aiGAaaGAvvGaliG 22 
                      aiG+a+G ++Ga++ 
       EEA22325.1 199 AIGTALGPILGAVFS 213
                      9***********997 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.065
                      XXXXXXXXX CS
  Gly-zipper_YMGG  14 GAvvGaliG 22 
                      GA+vG +iG
       EEA22325.1 465 GALVGLAIG 473
                      555555555 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0      0.35     1e+03     458     505 ..      59     107 ..      13     124 .. 0.45
   2 ?   12.3   4.5   1.3e-05     0.038     132     193 ..     153     214 ..     144     277 .. 0.82
   3 ?    4.0   1.3    0.0041        12     288     343 ..     317     372 ..     301     410 .. 0.78
   4 ?    1.0   1.3     0.032        97     139     192 ..     423     477 ..     411     487 .. 0.73

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.35
                 xxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 458 kklllflillflvsflgalg.rvpallvilRcVkkedksfalGlqllli 505
                 kkl ++l++l+l+ +++ ++   +al v + ++ ++    +l+  ++ i
  EEA22325.1  59 KKLSFYLAVLSLMLVILIVSlDATALSVAIPVITSDLNGTSLSAFWAGI 107
                 3444444444444443333213334445555555555555554444444 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 1.3e-05
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 132 vllfflaqlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllk 193
                 + +++l+ +++G+G+  +  l    i D ++ k+ plylg++++  ++G alG +lG+++ +
  EEA22325.1 153 MSILILGRVIQGLGGGGLDVLNEIIIADITTLKERPLYLGLMSVPMAIGTALGPILGAVFSE 214
                 4599******************************************************9976 PP

  == domain 3  score: 4.0 bits;  conditional E-value: 0.0041
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 288 krllknpifllvilssvfeillvaGfitFlpkylEtqFslsaseAnlltGvvvipg 343
                  r++++++ ++++l+s ++ +++  +  ++p + E+ F  ++  +++ + +++ ++
  EEA22325.1 317 YRIFRSRTAVVTLLGSFIHGMVLYTLLFYMPLFFESVFLETSLGSAISMLPLLCMV 372
                 589999********************************988776666543333332 PP

  == domain 4  score: 1.0 bits;  conditional E-value: 0.032
                 xxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 139 qlllGiGatpiytlGisYidDnv.kkknsplylgilyalrilGpalGfllGslll 192
                 q+++GiG   ++t+    +  ++ + ++  l +g+l ++r++G  +G ++Gs + 
  EEA22325.1 423 QVIAGIGMGSLFTVLPMPMQASApTAEDQGLAVGVLVSFRLFGALVGLAIGSTAF 477
                 56666665444444444444444145677899*******************9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (575 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       813  (0.0453455); expected 358.6 (0.02)
Passed bias filter:                      330  (0.0184059); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.74u 0.30s 00:00:01.04 Elapsed: 00:00:00.47
# Mc/sec: 3685.36
//
Query:       EEA22326.1  [L=298]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.8e-10   38.9   3.7    5.8e-10   38.9   3.7    1.7  2  Ses_B          SesB domain on fungal death-pathway protein
    1.4e-08   34.6   0.0    2.4e-08   33.7   0.0    1.4  1  DUF676         Putative serine esterase (DUF676)
    1.9e-05   25.4   0.0    2.2e-05   25.2   0.0    1.2  1  Abhydrolase_6  Alpha/beta hydrolase family
    0.00019   21.3   0.0    0.00035   20.4   0.0    1.4  1  PGAP1          PGAP1-like protein
     0.0086   15.2   0.0      0.013   14.6   0.0    1.2  1  Abhydrolase_9  Alpha/beta-hydrolase family
  ------ inclusion threshold ------
       0.16   10.9   0.0       0.28   10.1   0.0    1.3  1  DUF726         Protein of unknown function (DUF726)


Domain annotation for each model (and alignments):
>> Ses_B  SesB domain on fungal death-pathway protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       3.1   9.3e+03       1       8 [.     250     257 ..     250     257 .. 0.84
   2 !   38.9   3.7   1.9e-13   5.8e-10       2      28 .]     266     292 ..     265     292 .. 0.93

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 3.1
       Ses_B   1 tgwssmAs 8  
                 t+w s ++
  EEA22326.1 250 TQWASKIV 257
                 89**9875 PP

  == domain 2  score: 38.9 bits;  conditional E-value: 1.9e-13
       Ses_B   2 gwssmAsFSGSeNsGlQvGvnsGting 28 
                 ++ s+++FSGS+NsGlQ+G+n+Gt++g
  EEA22326.1 266 QNVSNTTFSGSHNSGLQLGQNVGTLKG 292
                 789*********************975 PP

>> DUF676  Putative serine esterase (DUF676)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.7   0.0   8.2e-12   2.4e-08       8     112 ..      16     125 ..      11     153 .. 0.77

  Alignments for each domain:
  == domain 1  score: 33.7 bits;  conditional E-value: 8.2e-12
      DUF676   8 vVlvHGlqgnsaDlelikeqleki...keklpee...kieflmsennesktfkgidvlgerlaeevlevvkkkkdknkkiSfvghSlGgliaraaiakl 100
                 +V+vHGl+g +a + + ++ +        k+ +     +e+ +   +  + ++gi+ + + l++e++++  +k++++  i fv+h lGg +   a+ ++
  EEA22326.1  16 IVFVHGLHGDQAPWTSEADVFWPEkllPAKVSDAcilSFEYEATIDSFFDEEDGITDISNDLINELMDHRTEKEKEERPIIFVAHCLGGTVLENALVRA 114
                 79********9999777776643222334455555557778888888999*********************99999999*****************998 PP

      DUF676 101 kekemtlkeaik 112
                  +++ + ke++ 
  EEA22326.1 115 ADHPRK-KELVG 125
                 877652.33333 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   0.0   7.5e-09   2.2e-05       1     117 [.      16     155 ..      16     263 .. 0.61

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 7.5e-09
                    EEEE--GC.....G...CHHHH..HHHHCCT...CEEEEE--TTSTS-GGCS--HHH.CHHH.HHHHCCTT.........TTSEEEEEETCHHHHH CS
  Abhydrolase_6   1 vlllHGagssassW...lvapL..aallaag...vhvlapDlpGhGrsdpppldled.ladl.aalldelaa.......gggpvvlvGHSlGGala 79 
                    ++++HG+ +++  W   + + +   +ll+a     ++l++ +  +    ++ +d ed + d+  +l++el +         +p++ v+H+lGG++ 
     EEA22326.1  16 IVFVHGLHGDQAPWtseA-DVFwpEKLLPAKvsdACILSFEYEAT---IDSFFDEEDgITDIsNDLINELMDhrtekekEERPIIFVAHCLGGTVL 107
                    8*****888899995431.32234333333322235588888777...555555555567776667777766777799899999**********88 PP

                    HHHHHCC.............EEEEES-..----TTTS----TTHHHHHH CS
  Abhydrolase_6  80 laaapla...........lvvgvlldppptalpagllaaalelllalla 117
                      a+  a            v+g+ll ++p  + ag laaa ++++ +  
     EEA22326.1 108 ENALVRAadhprkkelvgCVHGILLLGTP-HFQAGSLAAATKYFQLAQE 155
                    88555555777***999877884444433.5555554444444442222 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.0   1.2e-07   0.00035       7     133 ..      16     141 ..      11     176 .. 0.73

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 1.2e-07
       PGAP1   7 VlFvpGnagsykqvrslAseaaeayqelrkllknqnkkeldfftvdfneelsal.dGrtlldqaeylndaIkyIlslysssekeptsviliGHSmGGiv 104
                 ++Fv+G+ g    + s A++     +  +kll+ + ++    ++ +++  +  + d +     ++  nd+I+++++  +++eke++ +i ++H +GG v
  EEA22326.1  16 IVFVHGLHGDQAPWTSEADVF----W-PEKLLPAKVSD-ACILSFEYEATIDSFfDEEDG--ITDISNDLINELMDHRTEKEKEERPIIFVAHCLGGTV 106
                 788888888888888877777....4.44555555544.556666666666443033333..368889******************************* PP

       PGAP1 105 araaltlkn......yikqsvntiltlasPhalpp 133
                    al+ ++         + v+ il l++Ph ++ 
  EEA22326.1 107 LENALVRAAdhprkkELVGCVHGILLLGTPHFQAG 141
                 999888766555444556779**********8875 PP

>> Abhydrolase_9  Alpha/beta-hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   4.2e-06     0.013      69     149 ..      54     139 ..      46     157 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 4.2e-06
  Abhydrolase_9  69 YsylpSwlsflvdkekareagraLfeavyerwkelpedeRPkllvfGeSLGalgseaaf......seledllarvdgalwvGppnas 149
                    + y     sf+ +++  ++ ++ L++++ ++ +e+ ++eRP ++v+   LG +  e+a+       + ++l+  v+g+l++G+p+++
     EEA22326.1  54 FEYEATIDSFFDEEDGITDISNDLINELMDHRTEKEKEERPIIFVA-HCLGGTVLENALvraadhPRKKELVGCVHGILLLGTPHFQ 139
                    55666777999999999************************99886.7898888888874443334556788889*********986 PP

>> DUF726  Protein of unknown function (DUF726)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   9.5e-05      0.28     206     259 ..      80     137 ..      69     147 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 9.5e-05
      DUF726 206 lLAdallsraqGeRpvtLiGfslGARviyvCLlela....kkkalglvenvillGaPv 259
                  L d  +++++ eRp++ + + lG  v+   L   a    kk+ +g v  ++llG+P 
  EEA22326.1  80 ELMDHRTEKEKEERPIIFVAHCLGGTVLENALVRAAdhprKKELVGCVHGILLLGTPH 137
                 566677789999*******************9988722225688999**********6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (298 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       462  (0.0257683); expected 358.6 (0.02)
Passed bias filter:                      440  (0.0245412); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 1947.87
//
Query:       EEA22327.1  [L=527]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      1e-35  123.5   1.0      1e-35  123.5   1.0    2.5  2  HeLo      Prion-inhibition and propagation
    5.5e-16   59.1   5.6    1.5e-14   54.5   0.1    3.6  4  Goodbye   fungal STAND N-terminal Goodbye domain
      4e-06   26.7   7.0      4e-06   26.7   7.0    1.9  2  Ses_B     SesB domain on fungal death-pathway protein
  ------ inclusion threshold ------
       0.82    9.5   6.7       0.96    9.3   0.5    3.4  3  Sec34     Sec34-like family


Domain annotation for each model (and alignments):
>> HeLo  Prion-inhibition and propagation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.3     0.058   2.6e+02      67     107 ..      27      67 ..       9     188 .. 0.72
   2 !  123.5   1.0   2.3e-39     1e-35      12     197 ..     284     464 ..     281     472 .. 0.85

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.058
                 .....HHHHHHHHHHHHHHHHHHHHHHHHHHHH--CGG... CS
        HeLo  67 destrralvleileqiealleefeklqeryglklekqdass 107
                 +++t+++l l+ l++i ++++ +e l++ ++  ++++++++
  EEA22327.1  27 EKRTKKSLRLAQLSNIDQIMKGTEGLSDEFKDFRHDRSKTD 67 
                 33444556677788888888888888888887777666543 PP

  == domain 2  score: 123.5 bits;  conditional E-value: 2.3e-39
                 HHHHHHHTTTTEEEBGGGGGGHHHHHHHHHHHHHHHHHHHHHHTTT...-SHH..........HHHHHHHHHHHHHHHHHHHHHHHHHHHH--CGG... CS
        HeLo  12 lFsgcvkgfellsaarnlgkdyellrlkLdieqlRLlqWgeavgllspdsdkrld...destrralvleileqiealleefeklqeryglklekqdass 107
                 +F+++v+ f++++ ++nl+k +++ +lkLd+ +lRL +Wg++vgl++ ++ k l+      + r++v+ +l+qi +l+ ++e+ ++r++++  ++++  
  EEA22327.1 284 MFKDAVQSFGYIQMGANLDKSFQTSLLKLDVVRLRLTRWGQSVGLVNANDVKSLQitkLAPEDREQVQGLLDQILELFVDAEATSKRFKKRNGNSTT-- 380
                 7********************************************977743343332333333679*************************987653.. PP

                 ....G-B--GGGS-HHHHHHH.HHHHHHHHHS----S-----EEE-SHHHHHHHHHHHHHHHHHHHHTTT-H..HHHHHHHHHHCTT--. CS
        HeLo 108 sslalssereksfraefellkrlmrkaakkrqkrtslpkrlrWaivdkkkfeelvkdlkelvdsLeeLlpasqqqrvqrlvreeieqlsk 197
                        +  k++++  ++l++ m++ akkrq +    ++ +W+i+d+k+f++l++d++elvd+L +L+p   q+++++l++ee++ ++ 
  EEA22327.1 381 ----PVLDPAKELDSVSASLHQKMEDLAKKRQGKFD-LEQDKWTIYDEKNFTRLIEDISELVDGLVDLFPGI-QEEQRKLCEEEVSYMNT 464
                 ....3445668888999999988*********6666.5677*******************************.8**********988875 PP

>> Goodbye  fungal STAND N-terminal Goodbye domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.5   0.1   3.3e-18   1.5e-14       1     119 [.      19     142 ..      19     143 .. 0.87
   2 ?   -1.6   0.0      0.77   3.4e+03      51      83 ..     211     244 ..     199     246 .. 0.72
   3 ?   -2.0   0.0         1   4.7e+03      22      42 ..     266     286 ..     249     299 .. 0.52
   4 !    5.1   0.1    0.0065        29       4      48 ..     367     410 ..     365     445 .. 0.73

  Alignments for each domain:
  == domain 1  score: 54.5 bits;  conditional E-value: 3.3e-18
     Goodbye   1 WeeAlkeyekeTgkdlkdealkelssvedllkqieaekdkfeefr...ekkeklkealkkilspiqllggiaa..qgasmaFgP...aslcfnAvsyLi 91 
                 W++A+++yek+T+k+l   +l +ls++++++k  e  +d+f++fr   +k ++++ a+k+ l +iq++ + ++    a+ aF+P   asl+f+A   ++
  EEA22327.1  19 WQSAVEDYEKRTKKSL---RLAQLSNIDQIMKGTEGLSDEFKDFRhdrSKTDNMRTAFKNNLWLIQKIVNTVQvvGNAASAFPPampASLIFTAFGQVM 114
                 ****************...8888888888888888888877777766699999***************99876224566679976779*********** PP

     Goodbye  92 kaakkvseiydaieeLfeelsdflerle 119
                 +    vs+ yd+i   f+  + f  rl+
  EEA22327.1 115 QSFATVSADYDKIMGFFDFTHRFFDRLS 142
                 ******************9999999985 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.77
     Goodbye  51 lkealkkilspiqllggiaaqgasma.FgPaslc 83 
                 ++ ++  +l+ ++ l +i+++   ++ F  a+++
  EEA22327.1 211 AQAVGLATLRTVEILDDIVQSMNGNVeFLVAKVT 244
                 5667788999999999999988777766666655 PP

  == domain 3  score: -2.0 bits;  conditional E-value: 1
     Goodbye  22 kelssvedllkqieaekdkfe 42 
                 +  s+ +++++ +++++  f+
  EEA22327.1 266 ELESKQDAMMETLNEQSRMFK 286
                 222233334444444433333 PP

  == domain 4  score: 5.1 bits;  conditional E-value: 0.0065
     Goodbye   4 AlkeyekeTgkdlkdealkelssvedllkqieaekdkfeefrekk 48 
                 + k+++k+ g++  ++ l+++++++++++++ ++ +   ++r+ k
  EEA22327.1 367 TSKRFKKRNGNST-TPVLDPAKELDSVSASLHQKMEDLAKKRQGK 410
                 6799********9.99****************9999777777443 PP

>> Ses_B  SesB domain on fungal death-pathway protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.2       1.5   6.6e+03      18      24 ..       4      10 ..       4      11 .. 0.89
   2 !   26.7   7.0   8.9e-10     4e-06       1      28 []     495     521 ..     495     521 .. 0.96

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 1.5
       Ses_B 18 QvGvnsG 24
                Q+G+++G
  EEA22327.1  4 QIGNDAG 10
                99***98 PP

  == domain 2  score: 26.7 bits;  conditional E-value: 8.9e-10
       Ses_B   1 tgwssmAsFSGSeNsGlQvGvnsGting 28 
                 t+++++++FSG  NsG+Q+G+nsG+i+g
  EEA22327.1 495 TTYTNSVVFSGP-NSGFQIGNNSGKISG 521
                 799*********.*************86 PP

>> Sec34  Sec34-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0      0.14   6.3e+02      12      51 ..      42      77 ..      30     160 .. 0.66
   2 ?    9.3   0.5   0.00021      0.96      13     102 ..     223     313 ..     216     315 .. 0.82
   3 ?    0.8   0.3     0.089     4e+02      21      98 ..     349     430 ..     338     440 .. 0.58

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.14
       Sec34 12 cdelleqtdealeqLeeleekfksvsektsslheaceqll 51
                +d++++ t+ + +++++ +++     +kt ++++a ++ l
  EEA22327.1 42 IDQIMKGTEGLSDEFKDFRHD----RSKTDNMRTAFKNNL 77
                344444444444444444333....444444444444444 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.00021
       Sec34  13 delleqtdealeqLeeleekfksvsektsslheaceqlleeqkrleelaeeieekLkyFee.ldpitrkLnspgsslvksesFlemLkklD 102
                 + l + +++++ ++e l  k+++++e+t ++++++  ++e++++le+ ++++ e L+  +  ++ + +++   ++    ++sF++ L klD
  EEA22327.1 223 EILDDIVQSMNGNVEFLVAKVTFIDERTAAIKSDTGIIIEQNRELESKQDAMMETLNEQSRmFKDAVQSFGYIQMGANLDKSFQTSLLKLD 313
                 4455667899999*****************************************9987654146677778777777777788888888877 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.089
       Sec34  21 ealeqLeeleekfksvsektsslhe....aceqlleeqkrleelaeeieekLkyFeeldpitrkLnspgsslvksesFlemL 98 
                 +++ +L+++ e f + ++ ++++++    ++  +l+  k+l++++ ++++k++  ++  + +  L++ + ++ ++++F  ++
  EEA22327.1 349 QVQGLLDQILELFVDAEATSKRFKKrngnSTTPVLDPAKELDSVSASLHQKMEDLAKKRQGKFDLEQDKWTIYDEKNFTRLI 430
                 5555666666666666666666654111134555666666666666666666655555555555555555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (527 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1166  (0.0650343); expected 358.6 (0.02)
Passed bias filter:                      731  (0.0407719); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.44
# Mc/sec: 3624.39
//
Query:       EEA22328.1  [L=1026]
Description: TPR domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   7.3e-152  494.0  56.8    3.2e-23   81.8   0.2    9.4 10  TPR_12    Tetratricopeptide repeat
   1.7e-144  466.4  22.4    2.1e-15   56.0   0.1   12.3 12  TPR_10    Tetratricopeptide repeat
    6.1e-40  132.3  20.5    0.00021   21.1   0.0   11.6 11  TPR_7     Tetratricopeptide repeat
    2.8e-32  109.2  29.0    2.8e-05   23.7   0.1   11.6 11  TPR_1     Tetratricopeptide repeat
    5.8e-19   66.6  32.6      0.012   15.6   0.2   12.0 12  TPR_2     Tetratricopeptide repeat
    1.4e-18   65.6   0.0       0.32   11.7   0.0   10.2  9  TPR_4     Tetratricopeptide repeat
    1.5e-17   62.8  16.8        1.6    9.8   0.0   11.4 11  TPR_14    Tetratricopeptide repeat
    5.1e-16   59.0  24.0    2.5e-08   33.7   5.7    4.5  5  TPR_MalT  MalT-like TPR region
    2.7e-14   52.1  29.6       0.22   11.8   0.1   11.8 12  TPR_8     Tetratricopeptide repeat
    3.6e-13   49.9  25.1     0.0014   19.3   0.2    9.7  9  TPR_16    Tetratricopeptide repeat
    1.4e-10   41.2   8.8     0.0075   16.5   0.1    8.0  8  ANAPC3    Anaphase-promoting complex, cyclosome, subunit 3
    1.6e-10   41.3  25.6      0.021   15.3   0.3    6.8  6  TPR_19    Tetratricopeptide repeat
      9e-09   34.9   0.0    2.4e-07   30.2   0.0    2.3  1  NB-ARC    NB-ARC domain
    3.2e-07   30.3   9.7        7.7    7.1   0.1    9.8 11  TPR_17    Tetratricopeptide repeat
    8.5e-05   22.8  10.3        5.6    7.3   0.1    8.8 10  DUF1925   Domain of unknown function (DUF1925)
    0.00059   18.8   4.1      0.064   12.1   0.7    3.7  5  DUF3326   Protein of unknown function (DUF3326)
     0.0006   19.7   3.1     0.0012   18.7   3.1    1.5  1  Ses_B     SesB domain on fungal death-pathway protein
     0.0032   17.4   0.0     0.0085   16.0   0.0    1.8  1  NACHT     NACHT domain
     0.0033   17.5  17.3        3.2    7.9   0.0    8.7  9  MIT       MIT (microtubule interacting and transport) domain
  ------ inclusion threshold ------
        3.7    7.6  28.4        6.8    6.8   0.0    8.1 10  TPR_3     Tetratricopeptide repeat
        6.4    7.6  19.2        7.3    7.5   0.1    8.3  7  TPR_6     Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.3   0.3     9e-15   7.6e-12       4      77 .]     497     570 ..     495     570 .. 0.96
   2 !   67.2   0.5   1.3e-21   1.1e-18       2      77 .]     579     654 ..     578     654 .. 0.96
   3 !   56.0   1.1   4.1e-18   3.5e-15       5      76 ..     624     695 ..     622     696 .. 0.96
   4 !   58.0   0.8   9.9e-19   8.5e-16       5      77 .]     666     738 ..     662     738 .. 0.93
   5 !   71.0   0.2     9e-23   7.7e-20       4      76 ..     707     779 ..     704     780 .. 0.95
   6 !   64.0   2.4   1.3e-20   1.1e-17      12      77 .]     757     822 ..     757     822 .. 0.97
   7 !   72.6   0.6   2.8e-23   2.4e-20       2      77 .]     789     864 ..     788     864 .. 0.97
   8 !   71.1   1.2     8e-23   6.8e-20      12      77 .]     841     906 ..     840     906 .. 0.98
   9 !   81.8   0.2   3.7e-26   3.2e-23       3      77 .]     874     948 ..     872     948 .. 0.97
  10 !   20.4   0.0   5.4e-07   0.00046       7      47 ..     962    1002 ..     949    1006 .. 0.89

  Alignments for each domain:
  == domain 1  score: 45.3 bits;  conditional E-value: 9e-15
      TPR_12   4 talnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiaek 77 
                  +lnn a++ +  g+  eA+++   ++ + ++ lG +h+ t+++ +  g +++++g+y+eA++++++ala +ek
  EEA22328.1 497 LLLNNAALFALSKGNIIEAEKMAVNVMKATKEKLGSEHESTLSSTNMVGLVLDRQGKYKEAEAMHRQALATREK 570
                 578899****************************************************************9986 PP

  == domain 2  score: 67.2 bits;  conditional E-value: 1.3e-21
      TPR_12   2 vatalnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiaek 77 
                 ++++++nl +vl+++g+y+eA++++++ l++++r+lG dhp+t+t+  nLg ++ ++++y+eA+++ ++ala +ek
  EEA22328.1 579 TLISMSNLSLVLNKQGKYEEAEAIHRQTLAARERILGVDHPNTLTSIGNLGLILNRQKKYKEAEAMNRQALAGFEK 654
                 678889******************************************************************9885 PP

  == domain 3  score: 56.0 bits;  conditional E-value: 4.1e-18
      TPR_12   5 alnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                 +  nl+++l+r+++y eA+++ ++al+ ++++lG dhp+t+t++  Lg  ++++++yeeA++++++ala + 
  EEA22328.1 624 SIGNLGLILNRQKKYKEAEAMNRQALAGFEKVLGVDHPDTLTSRSILGFGLYMQEKYEEAEAMHRQALAGYN 695
                 5679*****************************************************************997 PP

  == domain 4  score: 58.0 bits;  conditional E-value: 9.9e-19
      TPR_12   5 alnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiaek 77 
                 + + l+  l+ +++y+eA++++++al+ ++++lG dhp+t t+  nLg +++++g+yeeA+ ++++ala +ek
  EEA22328.1 666 SRSILGFGLYMQEKYEEAEAMHRQALAGYNKVLGVDHPNTQTSIGNLGLVLDRQGKYEEAEVMHRQALAGFEK 738
                 55459999*************************************************************9885 PP

  == domain 5  score: 71.0 bits;  conditional E-value: 9e-23
      TPR_12   4 talnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                 t+  nl++vl r+g+y+eA+ ++++al+ ++++lG dhp+t+t++ nL+ +++++g+y+eA++++++ala + 
  EEA22328.1 707 TSIGNLGLVLDRQGKYEEAEVMHRQALAGFEKVLGVDHPNTLTSMDNLSLVLERQGKYKEAEAMHRQALAGYN 779
                 56779*****************************************************************997 PP

  == domain 6  score: 64.0 bits;  conditional E-value: 1.3e-20
      TPR_12  12 vlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiaek 77 
                 vl r+g+y eA++++++al+ ++++lG dhp+t+++l  Lg++++++g+yeeA+e+ ++ala +ek
  EEA22328.1 757 VLERQGKYKEAEAMHRQALAGYNKVLGADHPDTLASLSSLGTVLERQGKYEEAEEMNQQALATREK 822
                 689***********************************************************9986 PP

  == domain 7  score: 72.6 bits;  conditional E-value: 2.8e-23
      TPR_12   2 vatalnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiaek 77 
                 ++++l+ l++vl r+g+y+eA+e+ ++al+ ++++lG dhp+t++++ nL+ +++++g+yeeA+ +++++la ++k
  EEA22328.1 789 TLASLSSLGTVLERQGKYEEAEEMNQQALATREKVLGVDHPNTLASMDNLSLVLERQGKYEEAEVMYQRVLAGYKK 864
                 6788999*****************************************************************9986 PP

  == domain 8  score: 71.1 bits;  conditional E-value: 8e-23
      TPR_12  12 vlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiaek 77 
                 vl r+g+y+eA+ +++++l+ ++++lG dhp+t+++l nLg++++++g+y+eA++++++al+++ek
  EEA22328.1 841 VLERQGKYEEAEVMYQRVLAGYKKVLGADHPNTLASLSNLGMVLYRQGKYKEAEAMHRQALEVREK 906
                 899************************************************************986 PP

  == domain 9  score: 81.8 bits;  conditional E-value: 3.7e-26
      TPR_12   3 atalnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiaek 77 
                 +++l+nl++vl+r+g+y eA++++++ale+++++lG dhp+t+t++ nL+ +++ +g+yeeA+ ++++ala +ek
  EEA22328.1 874 LASLSNLGMVLYRQGKYKEAEAMHRQALEVREKVLGVDHPNTLTSMSNLSLVLDGQGKYEEAEPMHRQALAGYEK 948
                 67899*******************************************************************996 PP

  == domain 10  score: 20.4 bits;  conditional E-value: 5.4e-07
      TPR_12    7 nnlaavlrrlgrydeAlellekaleiarrllGpdhpltatt 47  
                  + l +vl ++gr deAle l++ +++++  lGpdhp+t+++
  EEA22328.1  962 RYLSVVLKKQGRRDEALEVLHTYIQLQQLKLGPDHPDTISA 1002
                  36999*********************************987 PP

>> TPR_10  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.3   0.0   0.00029      0.25       1      40 [.     495     534 ..     495     536 .. 0.96
   2 !   39.2   0.1   4.9e-13   4.2e-10       1      42 []     537     578 ..     537     578 .. 0.97
   3 !   45.8   0.1     4e-15   3.5e-12       1      42 []     579     620 ..     579     620 .. 0.96
   4 !   38.6   0.0   7.2e-13   6.2e-10       1      42 []     621     662 ..     621     662 .. 0.99
   5 !   34.3   0.0   1.6e-11   1.4e-08       1      42 []     663     704 ..     663     704 .. 0.97
   6 !   37.2   0.0   2.1e-12   1.8e-09       3      42 .]     707     746 ..     705     746 .. 0.95
   7 !   47.5   0.1   1.2e-15   9.9e-13       1      42 []     747     788 ..     747     788 .. 0.99
   8 !   44.9   0.1   7.6e-15   6.5e-12       1      42 []     789     830 ..     789     830 .. 0.98
   9 !   46.2   0.0   3.1e-15   2.7e-12       1      42 []     831     872 ..     831     872 .. 0.98
  10 !   56.0   0.1   2.5e-18   2.1e-15       1      42 []     873     914 ..     873     914 .. 0.98
  11 !   42.7   0.0   3.8e-14   3.3e-11       1      41 [.     915     955 ..     915     956 .. 0.97
  12 !   27.9   0.0   1.7e-09   1.5e-06       1      42 []     957     998 ..     957     998 .. 0.99

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00029
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdH 40 
                 +A  lnN a    + g+  eAe+++  ++ + ++ lG +H
  EEA22328.1 495 WALLLNNAALFALSKGNIIEAEKMAVNVMKATKEKLGSEH 534
                 7889**********************************99 PP

  == domain 2  score: 39.2 bits;  conditional E-value: 4.9e-13
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t+ss n  + +l ++g+y+eAea++++ala+r+++lG dH d
  EEA22328.1 537 TLSSTNMVGLVLDRQGKYKEAEAMHRQALATREKVLGVDHLD 578
                 8999************************************76 PP

  == domain 3  score: 45.8 bits;  conditional E-value: 4e-15
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t+ s++NL+ +l ++g+y+eAea+++++la+r+r+lG dHP+
  EEA22328.1 579 TLISMSNLSLVLNKQGKYEEAEAIHRQTLAARERILGVDHPN 620
                 6789*************************************5 PP

  == domain 4  score: 38.6 bits;  conditional E-value: 7.2e-13
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t++s  NL+ +l ++++y+eAea+ ++ala  +++lG dHPd
  EEA22328.1 621 TLTSIGNLGLILNRQKKYKEAEAMNRQALAGFEKVLGVDHPD 662
                 899**************************************9 PP

  == domain 5  score: 34.3 bits;  conditional E-value: 1.6e-11
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t++s++ L+  l+ + +y+eAea++++ala + ++lG dHP+
  EEA22328.1 663 TLTSRSILGFGLYMQEKYEEAEAMHRQALAGYNKVLGVDHPN 704
                 8999999**********************************5 PP

  == domain 6  score: 37.2 bits;  conditional E-value: 2.1e-12
      TPR_10   3 sslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 +s  NL+ +l ++g+y+eAe ++++ala  +++lG dHP+
  EEA22328.1 707 TSIGNLGLVLDRQGKYEEAEVMHRQALAGFEKVLGVDHPN 746
                 7889***********************************5 PP

  == domain 7  score: 47.5 bits;  conditional E-value: 1.2e-15
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t++s+ NL+ +l ++g+y+eAea++++ala + ++lG+dHPd
  EEA22328.1 747 TLTSMDNLSLVLERQGKYKEAEAMHRQALAGYNKVLGADHPD 788
                 89***************************************9 PP

  == domain 8  score: 44.9 bits;  conditional E-value: 7.6e-15
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t++sl+ L+ +l ++g+y+eAe++ ++ala+r+++lG dHP+
  EEA22328.1 789 TLASLSSLGTVLERQGKYEEAEEMNQQALATREKVLGVDHPN 830
                 89***************************************5 PP

  == domain 9  score: 46.2 bits;  conditional E-value: 3.1e-15
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t++s+ NL+ +l ++g+y+eAe +++++la ++++lG+dHP+
  EEA22328.1 831 TLASMDNLSLVLERQGKYEEAEVMYQRVLAGYKKVLGADHPN 872
                 89***************************************5 PP

  == domain 10  score: 56.0 bits;  conditional E-value: 2.5e-18
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t++sl+NL+++l+++g+y+eAea++++al++r+++lG dHP+
  EEA22328.1 873 TLASLSNLGMVLYRQGKYKEAEAMHRQALEVREKVLGVDHPN 914
                 89***************************************5 PP

  == domain 11  score: 42.7 bits;  conditional E-value: 3.8e-14
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHP 41 
                 t++s++NL+ +l  +g+y+eAe ++++ala ++++lG dH 
  EEA22328.1 915 TLTSMSNLSLVLDGQGKYEEAEPMHRQALAGYEKVLGVDHA 955
                 89**************************************5 PP

  == domain 12  score: 27.9 bits;  conditional E-value: 1.7e-09
      TPR_10   1 tAsslnNLanalrqrgrydeAealleealairrrllGpdHPd 42 
                 t++s+  L+++l ++gr+deA++ l+  +++++  lGpdHPd
  EEA22328.1 957 TLMSMRYLSVVLKKQGRRDEALEVLHTYIQLQQLKLGPDHPD 998
                 89***************************************9 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.6   0.0   6.2e-05     0.053       7      33 ..     546     572 ..     541     575 .. 0.85
   2 !   11.0   0.0   0.00042      0.36       3      32 ..     584     613 ..     582     617 .. 0.82
   3 !   10.0   0.0   0.00087      0.74       1      28 [.     624     651 ..     624     659 .. 0.86
   4 ?    5.2   0.1     0.029        25      13      30 ..     678     695 ..     674     701 .. 0.82
   5 !   15.2   0.0   1.9e-05     0.016       1      28 [.     708     735 ..     708     743 .. 0.86
   6 !   14.3   0.1   3.7e-05     0.031       3      30 ..     752     779 ..     750     785 .. 0.85
   7 !   21.1   0.0   2.4e-07   0.00021       1      33 [.     792     824 ..     792     827 .. 0.90
   8 !   12.3   0.1   0.00016      0.13       3      31 ..     836     864 ..     834     869 .. 0.85
   9 !   19.0   0.0   1.1e-06   0.00097       1      32 [.     876     907 ..     876     911 .. 0.89
  10 !   10.6   0.0   0.00057      0.49       3      29 ..     920     946 ..     918     953 .. 0.80
  11 ?    3.9   0.0     0.077        66       4      28 ..     963     990 ..     960     998 .. 0.74

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 6.2e-05
       TPR_7   7 rlysrlGdyeeAielyeqsLaltkdpe 33 
                  +  r+G+y+eA+  ++q+La+++  +
  EEA22328.1 546 LVLDRQGKYKEAEAMHRQALATREKVL 572
                 56789*************999998765 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 0.00042
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLaltkdp 32 
                 +nL  +  ++G+yeeA+ +++q La +++ 
  EEA22328.1 584 SNLSLVLNKQGKYEEAEAIHRQTLAARERI 613
                 677888889*************88877765 PP

  == domain 3  score: 10.0 bits;  conditional E-value: 0.00087
       TPR_7   1 aLlnLarlysrlGdyeeAielyeqsLal 28 
                 ++ nL+ +  r+ +y+eA+  ++q+La 
  EEA22328.1 624 SIGNLGLILNRQKKYKEAEAMNRQALAG 651
                 578*********************9964 PP

  == domain 4  score: 5.2 bits;  conditional E-value: 0.029
       TPR_7  13 GdyeeAielyeqsLaltk 30 
                  +yeeA+  ++q+La  +
  EEA22328.1 678 EKYEEAEAMHRQALAGYN 695
                 68**********998755 PP

  == domain 5  score: 15.2 bits;  conditional E-value: 1.9e-05
       TPR_7   1 aLlnLarlysrlGdyeeAielyeqsLal 28 
                 ++ nL+ +  r+G+yeeA+  ++q+La 
  EEA22328.1 708 SIGNLGLVLDRQGKYEEAEVMHRQALAG 735
                 578*********************9964 PP

  == domain 6  score: 14.3 bits;  conditional E-value: 3.7e-05
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLaltk 30 
                 +nL  + +r+G+y+eA+  ++q+La  +
  EEA22328.1 752 DNLSLVLERQGKYKEAEAMHRQALAGYN 779
                 799999****************998765 PP

  == domain 7  score: 21.1 bits;  conditional E-value: 2.4e-07
       TPR_7   1 aLlnLarlysrlGdyeeAielyeqsLaltkdpe 33 
                 +L+ L+ + +r+G+yeeA+e ++q+La+++  +
  EEA22328.1 792 SLSSLGTVLERQGKYEEAEEMNQQALATREKVL 824
                 6999********************999998765 PP

  == domain 8  score: 12.3 bits;  conditional E-value: 0.00016
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLaltkd 31 
                 +nL  + +r+G+yeeA+  y+++La  k 
  EEA22328.1 836 DNLSLVLERQGKYEEAEVMYQRVLAGYKK 864
                 799999****************9987665 PP

  == domain 9  score: 19.0 bits;  conditional E-value: 1.1e-06
       TPR_7   1 aLlnLarlysrlGdyeeAielyeqsLaltkdp 32 
                 +L+nL+ +  r+G+y+eA+  ++q+L++++  
  EEA22328.1 876 SLSNLGMVLYRQGKYKEAEAMHRQALEVREKV 907
                 79**********************99888765 PP

  == domain 10  score: 10.6 bits;  conditional E-value: 0.00057
       TPR_7   3 lnLarlysrlGdyeeAielyeqsLalt 29 
                 +nL  +   +G+yeeA+  ++q+La  
  EEA22328.1 920 SNLSLVLDGQGKYEEAEPMHRQALAGY 946
                 677777888*************99865 PP

  == domain 11  score: 3.9 bits;  conditional E-value: 0.077
       TPR_7   4 nLarlysrlGdyeeAielyeq..sL.al 28 
                 +L ++  ++G+++eA+e++    +L +l
  EEA22328.1 963 YLSVVLKKQGRRDEALEVLHTyiQLqQL 990
                 56778899*********98776655555 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.3   0.0   0.00059      0.51       8      29 ..     545     566 ..     542     570 .. 0.90
   2 ?    5.4   0.0     0.021        18      10      22 ..     589     601 ..     584     608 .. 0.85
   3 !   13.3   0.4   6.6e-05     0.056       6      28 ..     627     649 ..     624     650 .. 0.94
   4 !    6.7   0.3    0.0079       6.8       8      28 ..     671     691 ..     668     692 .. 0.88
   5 !   15.5   0.0   1.3e-05     0.011       6      28 ..     711     733 ..     708     734 .. 0.94
   6 !    7.2   0.2    0.0056       4.8      10      28 ..     757     775 ..     756     776 .. 0.90
   7 !   17.1   0.0     4e-06    0.0035       4      29 ..     793     818 ..     791     822 .. 0.90
   8 !   12.1   0.1   0.00016      0.13      10      28 ..     841     859 ..     840     860 .. 0.90
   9 !   23.7   0.1   3.3e-08   2.8e-05       3      32 ..     876     905 ..     875     906 .. 0.93
  10 ?    6.3   0.0      0.01       8.8      11      28 ..     926     943 ..     920     944 .. 0.87
  11 ?    2.0   0.0      0.24     2e+02      10      29 ..     967     986 ..     966     989 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00059
                 HHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1   8 GnayfklgkydeAleyyekALe 29 
                 G+++ ++gky+eA++  ++AL 
  EEA22328.1 545 GLVLDRQGKYKEAEAMHRQALA 566
                 8999****************97 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.021
                 HHHHTT-HHHHHH CS
       TPR_1  10 ayfklgkydeAle 22 
                 ++ k+gky+eA++
  EEA22328.1 589 VLNKQGKYEEAEA 601
                 789********86 PP

  == domain 3  score: 13.3 bits;  conditional E-value: 6.6e-05
                 HHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_1   6 nlGnayfklgkydeAleyyekAL 28 
                 nlG+++ +++ky+eA++  ++AL
  EEA22328.1 627 NLGLILNRQKKYKEAEAMNRQAL 649
                 9******************9999 PP

  == domain 4  score: 6.7 bits;  conditional E-value: 0.0079
                 HHHHHHTT-HHHHHHHHHHHH CS
       TPR_1   8 GnayfklgkydeAleyyekAL 28 
                 G  ++ ++ky+eA++  ++AL
  EEA22328.1 671 GFGLYMQEKYEEAEAMHRQAL 691
                 666899**************9 PP

  == domain 5  score: 15.5 bits;  conditional E-value: 1.3e-05
                 HHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_1   6 nlGnayfklgkydeAleyyekAL 28 
                 nlG+++ ++gky+eA+   ++AL
  EEA22328.1 711 NLGLVLDRQGKYEEAEVMHRQAL 733
                 9*********************9 PP

  == domain 6  score: 7.2 bits;  conditional E-value: 0.0056
                 HHHHTT-HHHHHHHHHHHH CS
       TPR_1  10 ayfklgkydeAleyyekAL 28 
                 ++ ++gky+eA++  ++AL
  EEA22328.1 757 VLERQGKYKEAEAMHRQAL 775
                 6789**************9 PP

  == domain 7  score: 17.1 bits;  conditional E-value: 4e-06
                 HHHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1   4 lynlGnayfklgkydeAleyyekALe 29 
                 l  lG ++ ++gky+eA+e  ++AL 
  EEA22328.1 793 LSSLGTVLERQGKYEEAEEMNQQALA 818
                 789*********************97 PP

  == domain 8  score: 12.1 bits;  conditional E-value: 0.00016
                 HHHHTT-HHHHHHHHHHHH CS
       TPR_1  10 ayfklgkydeAleyyekAL 28 
                 ++ ++gky+eA+  y+++L
  EEA22328.1 841 VLERQGKYEEAEVMYQRVL 859
                 6789*************99 PP

  == domain 9  score: 23.7 bits;  conditional E-value: 3.3e-08
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHST CS
       TPR_1   3 alynlGnayfklgkydeAleyyekALelnP 32 
                 +l nlG++++++gky+eA++  ++ALe+++
  EEA22328.1 876 SLSNLGMVLYRQGKYKEAEAMHRQALEVRE 905
                 589************************975 PP

  == domain 10  score: 6.3 bits;  conditional E-value: 0.01
                 HHHTT-HHHHHHHHHHHH CS
       TPR_1  11 yfklgkydeAleyyekAL 28 
                 +  +gky+eA+   ++AL
  EEA22328.1 926 LDGQGKYEEAEPMHRQAL 943
                 6679************99 PP

  == domain 11  score: 2.0 bits;  conditional E-value: 0.24
                 HHHHTT-HHHHHHHHHHHHH CS
       TPR_1  10 ayfklgkydeAleyyekALe 29 
                 ++ k+g+ deAle     ++
  EEA22328.1 967 VLKKQGRRDEALEVLHTYIQ 986
                 689*********97666555 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.1       4.6     4e+03       1      22 [.     496     517 ..     496     519 .. 0.88
   2 ?    5.3   0.1     0.029        24       7      23 ..     544     560 ..     542     568 .. 0.81
   3 ?    2.5   0.0      0.23     2e+02       6      21 ..     585     600 ..     581     602 .. 0.81
   4 ?    1.5   0.2      0.48   4.1e+02       6      22 ..     627     643 ..     625     650 .. 0.84
   5 ?    4.8   0.3     0.041        35       7      22 ..     670     685 ..     668     692 .. 0.83
   6 !    8.2   0.1    0.0035         3       6      21 ..     711     726 ..     709     734 .. 0.91
   7 !    7.1   0.1    0.0075       6.4       6      22 ..     753     769 ..     750     776 .. 0.83
   8 !   10.0   0.0   0.00091      0.78       4      28 ..     793     817 ..     791     821 .. 0.83
   9 !   12.5   0.0   0.00015      0.12       5      29 ..     836     860 ..     833     860 .. 0.91
  10 !   15.6   0.2   1.4e-05     0.012       4      29 ..     877     902 ..     875     906 .. 0.86
  11 ?    4.3   0.0      0.06        51       5      21 ..     920     936 ..     917     944 .. 0.87
  12 !    7.5   0.0    0.0056       4.8       5      30 ..     962     987 ..     960     989 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 4.6
       TPR_2   1 aealynlGlayyklgdyeeAle 22 
                 a +l+n +l ++ +g+  eA++
  EEA22328.1 496 ALLLNNAALFALSKGNIIEAEK 517
                 56899999999*****999986 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.029
       TPR_2   7 lGlayyklgdyeeAlea 23 
                  Gl++ ++g+y+eA++ 
  EEA22328.1 544 VGLVLDRQGKYKEAEAM 560
                 6999**********975 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.23
       TPR_2   6 nlGlayyklgdyeeAl 21 
                 nl l++ k+g+yeeA+
  EEA22328.1 585 NLSLVLNKQGKYEEAE 600
                 67777779*******7 PP

  == domain 4  score: 1.5 bits;  conditional E-value: 0.48
       TPR_2   6 nlGlayyklgdyeeAle 22 
                 nlGl++ ++++y+eA++
  EEA22328.1 627 NLGLILNRQKKYKEAEA 643
                 7999999********86 PP

  == domain 5  score: 4.8 bits;  conditional E-value: 0.041
       TPR_2   7 lGlayyklgdyeeAle 22 
                 lG  +y + +yeeA++
  EEA22328.1 670 LGFGLYMQEKYEEAEA 685
                 8999**********87 PP

  == domain 6  score: 8.2 bits;  conditional E-value: 0.0035
       TPR_2   6 nlGlayyklgdyeeAl 21 
                 nlGl++ ++g+yeeA+
  EEA22328.1 711 NLGLVLDRQGKYEEAE 726
                 89*************7 PP

  == domain 7  score: 7.1 bits;  conditional E-value: 0.0075
       TPR_2   6 nlGlayyklgdyeeAle 22 
                 nl l+++++g+y+eA++
  EEA22328.1 753 NLSLVLERQGKYKEAEA 769
                 899************87 PP

  == domain 8  score: 10.0 bits;  conditional E-value: 0.00091
       TPR_2   4 lynlGlayyklgdyeeAleafekAl 28 
                 l  lG +++++g+yeeA+e  ++Al
  EEA22328.1 793 LSSLGTVLERQGKYEEAEEMNQQAL 817
                 6679*************99666665 PP

  == domain 9  score: 12.5 bits;  conditional E-value: 0.00015
       TPR_2   5 ynlGlayyklgdyeeAleafekAle 29 
                  nl l+++++g+yeeA+  ++++l+
  EEA22328.1 836 DNLSLVLERQGKYEEAEVMYQRVLA 860
                 5899******************985 PP

  == domain 10  score: 15.6 bits;  conditional E-value: 1.4e-05
       TPR_2   4 lynlGlayyklgdyeeAleafekAle 29 
                 l nlG+++y++g+y+eA++  ++Ale
  EEA22328.1 877 LSNLGMVLYRQGKYKEAEAMHRQALE 902
                 88***************987777776 PP

  == domain 11  score: 4.3 bits;  conditional E-value: 0.06
       TPR_2   5 ynlGlayyklgdyeeAl 21 
                  nl l++  +g+yeeA+
  EEA22328.1 920 SNLSLVLDGQGKYEEAE 936
                 69999***********7 PP

  == domain 12  score: 7.5 bits;  conditional E-value: 0.0056
       TPR_2   5 ynlGlayyklgdyeeAleafekAlel 30 
                  +l  ++ k+g+ +eAle +   ++l
  EEA22328.1 962 RYLSVVLKKQGRRDEALEVLHTYIQL 987
                 68999*************99888877 PP

>> TPR_4  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.0      0.52   4.5e+02       9      23 ..     546     560 ..     545     563 .. 0.86
   2 ?    5.3   0.0     0.045        38       5      23 ..     584     602 ..     581     605 .. 0.89
   3 ?    6.1   0.0     0.026        22       6      22 ..     711     727 ..     710     731 .. 0.90
   4 ?    3.2   0.0      0.21   1.8e+02       6      23 ..     753     770 ..     751     773 .. 0.88
   5 !    7.5   0.0     0.009       7.6       3      23 ..     792     812 ..     790     812 .. 0.89
   6 ?    4.9   0.0     0.062        53       6      26 .]     837     857 ..     833     857 .. 0.87
   7 !   11.7   0.0   0.00038      0.32       2      23 ..     875     896 ..     874     899 .. 0.90
   8 ?    3.5   0.0      0.17   1.5e+02       5      22 ..     920     937 ..     917     941 .. 0.87
   9 ?    6.2   0.0     0.024        20       7      25 ..     964     982 ..     959     983 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.52
       TPR_4   9 rallalGdldeAral 23 
                  +l ++G + eA+a+
  EEA22328.1 546 LVLDRQGKYKEAEAM 560
                 6899*********97 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.045
       TPR_4   5 laLArallalGdldeAral 23 
                 ++L  +l  +G ++eA+a+
  EEA22328.1 584 SNLSLVLNKQGKYEEAEAI 602
                 79999************96 PP

  == domain 3  score: 6.1 bits;  conditional E-value: 0.026
       TPR_4   6 aLArallalGdldeAra 22 
                 +L+ +l ++G ++eA+ 
  EEA22328.1 711 NLGLVLDRQGKYEEAEV 727
                 89*************96 PP

  == domain 4  score: 3.2 bits;  conditional E-value: 0.21
       TPR_4   6 aLArallalGdldeAral 23 
                 +L  +l ++G + eA+a+
  EEA22328.1 753 NLSLVLERQGKYKEAEAM 770
                 688899**********97 PP

  == domain 5  score: 7.5 bits;  conditional E-value: 0.009
       TPR_4   3 allaLArallalGdldeAral 23 
                  l+ L+ +l ++G ++eA+++
  EEA22328.1 792 SLSSLGTVLERQGKYEEAEEM 812
                 6889**************985 PP

  == domain 6  score: 4.9 bits;  conditional E-value: 0.062
       TPR_4   6 aLArallalGdldeAraller 26 
                 +L  +l ++G ++eA+ + +r
  EEA22328.1 837 NLSLVLERQGKYEEAEVMYQR 857
                 68899***********98765 PP

  == domain 7  score: 11.7 bits;  conditional E-value: 0.00038
       TPR_4   2 rallaLArallalGdldeAral 23 
                 + l++L+++l+++G + eA+a+
  EEA22328.1 875 ASLSNLGMVLYRQGKYKEAEAM 896
                 5789****************97 PP

  == domain 8  score: 3.5 bits;  conditional E-value: 0.17
       TPR_4   5 laLArallalGdldeAra 22 
                 ++L  +l  +G ++eA+ 
  EEA22328.1 920 SNLSLVLDGQGKYEEAEP 937
                 79999***********96 PP

  == domain 9  score: 6.2 bits;  conditional E-value: 0.024
       TPR_4   7 LArallalGdldeAralle 25 
                 L  +l  +G+ deA+++l+
  EEA22328.1 964 LSVVLKKQGRRDEALEVLH 982
                 6678889*********995 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.7   0.0    0.0041       3.5       8      33 ..     545     570 ..     541     576 .. 0.87
   2 ?    0.5   0.1       1.8   1.5e+03       9      30 ..     588     609 ..     586     616 .. 0.81
   3 ?   -0.5   0.0       3.8   3.2e+03       7      29 ..     628     650 ..     628     663 .. 0.81
   4 ?    1.6   0.0      0.77   6.6e+02      11      29 ..     674     692 ..     667     704 .. 0.83
   5 ?    5.5   0.0     0.044        37       7      30 ..     712     735 ..     711     745 .. 0.87
   6 !    8.8   0.2    0.0037       3.1       9      29 ..     756     776 ..     753     794 .. 0.81
   7 ?    7.3   0.1     0.012        10       6      32 ..     795     821 ..     790     826 .. 0.85
   8 !    9.4   0.0    0.0025       2.1       8      30 ..     839     861 ..     836     873 .. 0.85
   9 !    9.8   0.0    0.0018       1.6       7      31 ..     880     904 ..     874     913 .. 0.87
  10 ?    2.5   0.0      0.41   3.5e+02      10      30 ..     925     945 ..     922     958 .. 0.81
  11 ?    6.1   0.0     0.028        24       7      34 ..     964     996 ..     960    1002 .. 0.76

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.0041
      TPR_14   8 aeallalGdpdeAiallrralalaPd 33 
                 + +l ++G+++eA+a+ r+ala+  +
  EEA22328.1 545 GLVLDRQGKYKEAEAMHRQALATREK 570
                 67899****************98765 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 1.8
      TPR_14   9 eallalGdpdeAiallrralal 30 
                  +l  +G+++eA+a+ r+ la+
  EEA22328.1 588 LVLNKQGKYEEAEAIHRQTLAA 609
                 578899*******998887665 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 3.8
      TPR_14   7 laeallalGdpdeAiallrrala 29 
                 l+ +l ++ +++eA+a+ r+ala
  EEA22328.1 628 LGLILNRQKKYKEAEAMNRQALA 650
                 57789999*******99888877 PP

  == domain 4  score: 1.6 bits;  conditional E-value: 0.77
      TPR_14  11 llalGdpdeAiallrrala 29 
                 l+ +++++eA+a+ r+ala
  EEA22328.1 674 LYMQEKYEEAEAMHRQALA 692
                 667889***********98 PP

  == domain 5  score: 5.5 bits;  conditional E-value: 0.044
      TPR_14   7 laeallalGdpdeAiallrralal 30 
                 l+ +l ++G+++eA+ + r+ala 
  EEA22328.1 712 LGLVLDRQGKYEEAEVMHRQALAG 735
                 688999***************985 PP

  == domain 6  score: 8.8 bits;  conditional E-value: 0.0037
      TPR_14   9 eallalGdpdeAiallrrala 29 
                  +l+++G+++eA+a+ r+ala
  EEA22328.1 756 LVLERQGKYKEAEAMHRQALA 776
                 689****************99 PP

  == domain 7  score: 7.3 bits;  conditional E-value: 0.012
      TPR_14   6 alaeallalGdpdeAiallrralalaP 32 
                  l+ +l+++G+++eA+++ ++ala+  
  EEA22328.1 795 SLGTVLERQGKYEEAEEMNQQALATRE 821
                 6899*************9999988765 PP

  == domain 8  score: 9.4 bits;  conditional E-value: 0.0025
      TPR_14   8 aeallalGdpdeAiallrralal 30 
                   +l+++G+++eA+ +++r+la 
  EEA22328.1 839 SLVLERQGKYEEAEVMYQRVLAG 861
                 5689****************984 PP

  == domain 9  score: 9.8 bits;  conditional E-value: 0.0018
      TPR_14   7 laeallalGdpdeAiallrralala 31 
                 l+ +l+++G+++eA+a+ r+al+  
  EEA22328.1 880 LGMVLYRQGKYKEAEAMHRQALEVR 904
                 7889******************965 PP

  == domain 10  score: 2.5 bits;  conditional E-value: 0.41
      TPR_14  10 allalGdpdeAiallrralal 30 
                 +l  +G+++eA+ + r+ala 
  EEA22328.1 925 VLDGQGKYEEAEPMHRQALAG 945
                 566699************985 PP

  == domain 11  score: 6.1 bits;  conditional E-value: 0.028
      TPR_14   7 laeallalGdpdeAiallrrala.....laPdd 34 
                 l  +l  +G+ deA+++l+ +++     l+Pd+
  EEA22328.1 964 LSVVLKKQGRRDEALEVLHTYIQlqqlkLGPDH 996
                 4558999*************9884444445665 PP

>> TPR_MalT  MalT-like TPR region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   1.9   1.5e-06    0.0013       8     154 ..     503     654 ..     500     664 .. 0.87
   2 !   10.2   0.5    0.0004      0.34      10     108 ..     631     734 ..     627     744 .. 0.86
   3 !   20.4   3.6   3.3e-07   0.00028      13     155 ..     676     823 ..     669     828 .. 0.86
   4 !   33.7   5.7   2.9e-11   2.5e-08      14     189 ..     761     944 ..     755     948 .. 0.88
   5 !   13.9   0.3     3e-05     0.026      42     116 ..     918     994 ..     910    1000 .. 0.81

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 1.5e-06
    TPR_MalT   8 AllaiasgdaeralelArqALallped...dllariaatavlGeasllqGdleaAlqalqeaekl...arqadslhvallallqqaeilvaqGrLheAl 100
                 Al a+++g++ +a+++A + ++ ++e+   ++ + +  t ++G +   qG+ ++A++++++a ++    ++ d+l+ +l ++  ++ +l +qG+ +eA+
  EEA22328.1 503 ALFALSKGNIIEAEKMAVNVMKATKEKlgsEHESTLSSTNMVGLVLDRQGKYKEAEAMHRQALATrekVLGVDHLD-TLISMSNLSLVLNKQGKYEEAE 600
                 7889********************986333778888888999******************9997633345555555.9********************* PP

    TPR_MalT 101 etyeqalqlateqglqqlplvgfllvlladllyEwndLeeAeqhlqeGielleq 154
                  + +q l+  ++  +   p        l+ +l  + + +eAe + +++++  e+
  EEA22328.1 601 AIHRQTLAARERILGVDHPNTLTSIGNLGLILNRQKKYKEAEAMNRQALAGFEK 654
                 *************9999999999999******************9999876665 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.0004
    TPR_MalT  10 laiasgdaeralelArqALallpe...ddllariaatavlGeasllqGdleaAlqalqeaekl...arqadslhvallallqqaeilvaqGrLheAlet 102
                 +   + + ++a+++ rqALa +++    d++  ++ +++lG    +q++ e+A++++++a +     ++ d+++ +++++  ++ +l  qG+ +eA+ +
  EEA22328.1 631 ILNRQKKYKEAEAMNRQALAGFEKvlgVDHPDTLTSRSILGFGLYMQEKYEEAEAMHRQALAGynkVLGVDHPN-TQTSIGNLGLVLDRQGKYEEAEVM 728
                 6667888999*********99987333699*****************************997422255666666.9*********************** PP

    TPR_MalT 103 yeqalq 108
                  +qal+
  EEA22328.1 729 HRQALA 734
                 ***996 PP

  == domain 3  score: 20.4 bits;  conditional E-value: 3.3e-07
    TPR_MalT  13 asgdaeralelArqALa....llpeddllariaatavlGeasllqGdleaAlqalqeaek.l..arqadslhvallallqqaeilvaqGrLheAletye 104
                 ++++ e+a+++ rqALa     l  d   +++ +  +lG +   qG+ e+A+ ++++a + +   ++ d+++ +l+++  ++ +l  qG+ +eA+ + +
  EEA22328.1 676 MQEKYEEAEAMHRQALAgynkVLGVDHPNTQTSI-GNLGLVLDRQGKYEEAEVMHRQALAgFekVLGVDHPN-TLTSMDNLSLVLERQGKYKEAEAMHR 772
                 6889999999999999833324555666666666.9**********************98442245555555.9************************* PP

    TPR_MalT 105 qalqlateqglqqlplvgfllvlladllyEwndLeeAeqhlqeGielleql 155
                 qal+ + +  ++  p     l +l+ +l  +++ eeAe++ q++++  e++
  EEA22328.1 773 QALAGYNKVLGADHPDTLASLSSLGTVLERQGKYEEAEEMNQQALATREKV 823
                 ***************999999***********************9988776 PP

  == domain 4  score: 33.7 bits;  conditional E-value: 2.9e-11
    TPR_MalT  14 sgdaeralelArqALallpe...ddllariaatavlGeasllqGdleaAlqalqeaekl...arqadslhvallallqqaeilvaqGrLheAletyeqa 106
                 +g+ ++a+++ rqALa   +    d++  +a +++lG++   qG+ e+A+++ q+a ++    ++ d+++ +l ++  ++ +l  qG+ +eA+ +y++ 
  EEA22328.1 761 QGKYKEAEAMHRQALAGYNKvlgADHPDTLASLSSLGTVLERQGKYEEAEEMNQQALATrekVLGVDHPN-TLASMDNLSLVLERQGKYEEAEVMYQRV 858
                 7899999999999998776433389*****************************9987643356666666.9*************************** PP

    TPR_MalT 107 lqlateqglqqlplvgfllvlladllyEwndLeeAeqhlqeGielleql...epeaaldayvllarialaqGdleeAetllekaee 189
                 l+ +++  ++  p     l  l+ +ly +++ +eAe + ++++e+ e++   +   +l +   l  +   qG+ eeAe + ++a +
  EEA22328.1 859 LAGYKKVLGADHPNTLASLSNLGMVLYRQGKYKEAEAMHRQALEVREKVlgvDHPNTLTSMSNLSLVLDGQGKYEEAEPMHRQALA 944
                 ************************************************8643345678899999999999*******999999865 PP

  == domain 5  score: 13.9 bits;  conditional E-value: 3e-05
    TPR_MalT  42 atavlGeasllqGdleaAlqalqeaek.larqadslhv.allallqqaeilvaqGrLheAletyeqalqlateqglq 116
                  +++l  +   qG+ e+A+ ++++a +   +  +  h+ +l+++++++ +l +qGr +eAle+ +  +ql + + ++
  EEA22328.1 918 SMSNLSLVLDGQGKYEEAEPMHRQALAgYEKVLGVDHAmTLMSMRYLSVVLKKQGRRDEALEVLHTYIQLQQLKLGP 994
                 556666667789999********99983457777777768****************************999877665 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0       5.6   4.7e+03       4      22 ..     499     517 ..     497     522 .. 0.88
   2 ?    5.0   0.0     0.039        33       6      28 ..     543     565 ..     540     570 .. 0.87
   3 ?    5.4   0.1     0.029        25       6      22 ..     585     601 ..     582     605 .. 0.89
   4 ?    6.6   0.2     0.012        10       5      28 ..     626     649 ..     622     650 .. 0.87
   5 ?   -2.3   0.4       8.5   7.2e+03      15      28 ..     678     691 ..     677     692 .. 0.82
   6 !    7.0   0.0     0.009       7.7       5      27 ..     710     732 ..     707     734 .. 0.83
   7 ?    5.5   0.1     0.027        23       5      28 ..     752     775 ..     748     776 .. 0.87
   8 ?    6.7   0.1     0.011       9.4       6      28 ..     795     817 ..     790     822 .. 0.84
   9 !    8.5   0.1    0.0031       2.6       5      28 ..     836     859 ..     832     860 .. 0.90
  10 !   11.8   0.1   0.00026      0.22       3      32 ..     876     905 ..     874     907 .. 0.90
  11 ?    5.2   0.0     0.035        30       4      28 ..     919     943 ..     916     944 .. 0.84
  12 ?    1.5   0.0      0.52   4.4e+02       8      30 ..     965     987 ..     964     989 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 5.6
                 HHHHHHHHHHTT-HHHHHH CS
       TPR_8   4 yynlgsiylklgdyeeAke 22 
                 ++n ++  l++g++ eA++
  EEA22328.1 499 LNNAALFALSKGNIIEAEK 517
                 68999999******99987 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.039
                 HHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_8   6 nlgsiylklgdyeeAkeyyekal 28 
                 + g++++ +g+y+eA++  ++al
  EEA22328.1 543 MVGLVLDRQGKYKEAEAMHRQAL 565
                 67999************999988 PP

  == domain 3  score: 5.4 bits;  conditional E-value: 0.029
                 HHHHHHHHTT-HHHHHH CS
       TPR_8   6 nlgsiylklgdyeeAke 22 
                 nl++++ k+g+yeeA++
  EEA22328.1 585 NLSLVLNKQGKYEEAEA 601
                 899************97 PP

  == domain 4  score: 6.6 bits;  conditional E-value: 0.012
                 HHHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_8   5 ynlgsiylklgdyeeAkeyyekal 28 
                  nlg+i+  +++y+eA++  ++al
  EEA22328.1 626 GNLGLILNRQKKYKEAEAMNRQAL 649
                 69***************9877776 PP

  == domain 5  score: -2.3 bits;  conditional E-value: 8.5
                 T-HHHHHHHHHHHH CS
       TPR_8  15 gdyeeAkeyyekal 28 
                 ++yeeA++  ++al
  EEA22328.1 678 EKYEEAEAMHRQAL 691
                 68****99888876 PP

  == domain 6  score: 7.0 bits;  conditional E-value: 0.009
                 HHHHHHHHHTT-HHHHHHHHHHH CS
       TPR_8   5 ynlgsiylklgdyeeAkeyyeka 27 
                  nlg++++ +g+yeeA+   ++a
  EEA22328.1 710 GNLGLVLDRQGKYEEAEVMHRQA 732
                 69**************9766665 PP

  == domain 7  score: 5.5 bits;  conditional E-value: 0.027
                 HHHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_8   5 ynlgsiylklgdyeeAkeyyekal 28 
                  nl+++++ +g+y+eA++  ++al
  EEA22328.1 752 DNLSLVLERQGKYKEAEAMHRQAL 775
                 5899*************9988886 PP

  == domain 8  score: 6.7 bits;  conditional E-value: 0.011
                 HHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_8   6 nlgsiylklgdyeeAkeyyekal 28 
                  lg +++ +g+yeeA+e  ++al
  EEA22328.1 795 SLGTVLERQGKYEEAEEMNQQAL 817
                 6999************9877776 PP

  == domain 9  score: 8.5 bits;  conditional E-value: 0.0031
                 HHHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_8   5 ynlgsiylklgdyeeAkeyyekal 28 
                  nl+++++ +g+yeeA+  y+++l
  EEA22328.1 836 DNLSLVLERQGKYEEAEVMYQRVL 859
                 5899****************9987 PP

  == domain 10  score: 11.8 bits;  conditional E-value: 0.00026
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAkeyyekaleldp 32 
                 ++ nlg+++  +g+y+eA++  ++ale ++
  EEA22328.1 876 SLSNLGMVLYRQGKYKEAEAMHRQALEVRE 905
                 5679**********************9887 PP

  == domain 11  score: 5.2 bits;  conditional E-value: 0.035
                 HHHHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_8   4 yynlgsiylklgdyeeAkeyyekal 28 
                 + nl+++++ +g+yeeA+   ++al
  EEA22328.1 919 MSNLSLVLDGQGKYEEAEPMHRQAL 943
                 56999************98777776 PP

  == domain 12  score: 1.5 bits;  conditional E-value: 0.52
                 HHHHHHTT-HHHHHHHHHHHHHH CS
       TPR_8   8 gsiylklgdyeeAkeyyekalel 30 
                 + +++k+g+ +eA e++  +++l
  EEA22328.1 965 SVVLKKQGRRDEALEVLHTYIQL 987
                 56899*********998777766 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.1       0.1        87       4      25 ..     545     566 ..     531     570 .. 0.70
   2 ?    5.3   1.0     0.037        31       4      55 ..     545     601 ..     542     610 .. 0.76
   3 ?    6.7   0.2     0.013        11       9      61 ..     592     649 ..     585     654 .. 0.79
   4 ?    4.4   0.3      0.07        60      41      61 ..     629     649 ..     627     697 .. 0.52
   5 ?    4.4   0.1     0.072        61      25      54 ..     699     726 ..     673     728 .. 0.65
   6 ?    5.0   0.8     0.047        40       4      55 ..     713     769 ..     711     780 .. 0.56
   7 !   15.0   0.8   3.3e-05     0.029       6      62 ..     757     818 ..     753     822 .. 0.82
   8 !   19.3   0.2   1.6e-06    0.0014       5      55 ..     840     895 ..     837     905 .. 0.83
   9 !    7.2   0.1    0.0093       7.9       7      60 ..     926     984 ..     921     997 .. 0.79

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.1
      TPR_16   4 araalragdyddAaaaleaalk 25 
                 ++ + r+g+y +A+a+ ++al+
  EEA22328.1 545 GLVLDRQGKYKEAEAMHRQALA 566
                 4555666666666666666665 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.037
      TPR_16   4 araalragdyddAaaaleaalkrdpssPd........aaeAllllgdaalrqgrlaeAaa 55 
                 ++ + r+g+y +A+a+ ++al+ +             +  ++ +l +++ +qg ++eA+a
  EEA22328.1 545 GLVLDRQGKYKEAEAMHRQALATR---EKvlgvdhldTLISMSNLSLVLNKQGKYEEAEA 601
                 677889999999999999999877...333456666688888888888888888888875 PP

  == domain 3  score: 6.7 bits;  conditional E-value: 0.013
      TPR_16   9 ragdyddAaaaleaalkrdpssPd........aaeAllllgdaalrqgrlaeAaalyraal 61 
                 ++g+y++A+a  +++l+++    +        +  +  +lg+++ rq+ ++eA+a  r al
  EEA22328.1 592 KQGKYEEAEAIHRQTLAAR---ERilgvdhpnTLTSIGNLGLILNRQKKYKEAEAMNRQAL 649
                 6888888888888888887...44444555558888999**************99888887 PP

  == domain 4  score: 4.4 bits;  conditional E-value: 0.07
      TPR_16  41 gdaalrqgrlaeAaalyraal 61 
                 g+++ rq+ ++eA+a  r al
  EEA22328.1 629 GLILNRQKKYKEAEAMNRQAL 649
                 444444444444444444443 PP

  == domain 5  score: 4.4 bits;  conditional E-value: 0.072
      TPR_16  25 krdpssPdaaeAllllgdaalrqgrlaeAa 54 
                   d  +P +  +  +lg+++ rqg ++eA+
  EEA22328.1 699 GVD--HPNTQTSIGNLGLVLDRQGKYEEAE 726
                 333..5667777778999999999999986 PP

  == domain 6  score: 5.0 bits;  conditional E-value: 0.047
      TPR_16   4 araalragdyddAaaaleaalkrdpssPd........aaeAllllgdaalrqgrlaeAaa 55 
                 ++ + r+g+y++A+ + ++al+ +             +  ++ +l +++ rqg ++eA+a
  EEA22328.1 713 GLVLDRQGKYEEAEVMHRQALAGFE---KvlgvdhpnTLTSMDNLSLVLERQGKYKEAEA 769
                 5556666666666655566666552...12223333366666667777777777777765 PP

  == domain 7  score: 15.0 bits;  conditional E-value: 3.3e-05
      TPR_16   6 aalragdyddAaaaleaalk.....rdpssPdaaeAllllgdaalrqgrlaeAaalyraalr 62 
                  + r+g+y +A+a+ ++al+     +++++Pd+ ++l  lg ++ rqg ++eA++  + al+
  EEA22328.1 757 VLERQGKYKEAEAMHRQALAgynkvLGADHPDTLASLSSLGTVLERQGKYEEAEEMNQQALA 818
                 577899999999999888884444445789************************98888875 PP

  == domain 8  score: 19.3 bits;  conditional E-value: 1.6e-06
      TPR_16   5 raalragdyddAaaaleaalkrdp.....ssPdaaeAllllgdaalrqgrlaeAaa 55 
                 + + r+g+y++A+ +++++l+ ++     ++P + ++l +lg +++rqg ++eA+a
  EEA22328.1 840 LVLERQGKYEEAEVMYQRVLAGYKkvlgaDHPNTLASLSNLGMVLYRQGKYKEAEA 895
                 56889****************774222226777*********************97 PP

  == domain 9  score: 7.2 bits;  conditional E-value: 0.0093
      TPR_16   7 alragdyddAaaaleaalkrdpssPd........aaeAllllgdaalrqgrlaeAaalyraa 60 
                 +  +g+y++A+++ ++al+ +             +  ++ +l +++ +qgr +eA++++  +
  EEA22328.1 926 LDGQGKYEEAEPMHRQALAGY---EKvlgvdhamTLMSMRYLSVVLKKQGRRDEALEVLHTY 984
                 557999999999999999988...44466788889999999999999999999999877555 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.6   0.1    0.0053       4.5      19      77 ..     534     601 ..     509     606 .. 0.66
   2 ?    2.8   0.1      0.16   1.4e+02      30      50 ..     587     608 ..     575     644 .. 0.67
   3 ?    2.9   0.1      0.15   1.3e+02      25      76 ..     624     684 ..     607     690 .. 0.60
   4 ?    3.7   0.0     0.086        74       9      43 ..     684     726 ..     676     768 .. 0.64
   5 ?    4.0   0.1     0.067        57       5      49 ..     729     774 ..     719     785 .. 0.73
   6 ?    6.7   0.1      0.01       8.6       4      49 ..     763     816 ..     760     827 .. 0.74
   7 !   16.5   0.1   8.7e-06    0.0075       2      54 ..     845     906 ..     844     938 .. 0.85
   8 ?   -0.4   0.0       1.7   1.4e+03       5      49 ..     939     984 ..     929     991 .. 0.68

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0053
                 HH--HHHHHHHHHHHHHTT-HHHHHHHHHCT.SHHHC-H.....HHHHHHH...HHHHHTT-HHHHHH CS
      ANAPC3  19 etespedayllAlclylngqykrAyellrka.klnsksl.....gcrylfA...qcllkLkkyeeAia 77 
                 +   ++++ + +l+l ++g+yk+A    r+a  +++k l       ++ +     +l k++kyeeA+a
  EEA22328.1 534 HESTLSSTNMVGLVLDRQGKYKEAEAMHRQAlATREKVLgvdhlDTLISMSnlsLVLNKQGKYEEAEA 601
                 445566788889************99999997777776633322444444443233446688888876 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.16
                 HHHHHHTT-HHHHHHHHHCT.S CS
      ANAPC3  30 AlclylngqykrAyellrka.k 50 
                 +l+l ++g+y++A  + r++  
  EEA22328.1 587 SLVLNKQGKYEEAEAIHRQTlA 608
                 5666677777777776666633 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.15
                 HHHHHHHHHHHTT-HHHHHHHHHCT.SHHHC-H........HHHHHHHHHHHHTT-HHHHH CS
      ANAPC3  25 dayllAlclylngqykrAyellrka.klnsksl........gcrylfAqcllkLkkyeeAi 76 
                 ++  l+l l ++++yk+A    r+a    +k l         +r +++  l+ ++kyeeA+
  EEA22328.1 624 SIGNLGLILNRQKKYKEAEAMNRQAlAGFEKVLgvdhpdtlTSRSILGFGLYMQEKYEEAE 684
                 5555677777777777777666666444444333333344466666666666666666666 PP

  == domain 4  score: 3.7 bits;  conditional E-value: 0.086
                 HHHHHHHH.........HHH--HHHHHHHHHHHHHTT-HHHHH CS
      ANAPC3   9 iflaerll.......a.aetespedayllAlclylngqykrAy 43 
                 + +   +l          +++   ++  l+l+l ++g+y++A 
  EEA22328.1 684 EAMHRQALagynkvlGvDHPNTQTSIGNLGLVLDRQGKYEEAE 726
                 5555555533332222477777777777888888888888875 PP

  == domain 5  score: 4.0 bits;  conditional E-value: 0.067
                 HHHHHHHHHHHH..HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCT CS
      ANAPC3   5 yknAiflaerlla.aetespedayllAlclylngqykrAyellrka 49 
                 ++ A+  +e++l   +++ + +   l+l+l ++g+yk+A    r+a
  EEA22328.1 729 HRQALAGFEKVLGvDHPNTLTSMDNLSLVLERQGKYKEAEAMHRQA 774
                 555666666666447777777777799************9988887 PP

  == domain 6  score: 6.7 bits;  conditional E-value: 0.01
                 -HHHHHHHHHHHH.........HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCT CS
      ANAPC3   4 nyknAiflaerll........aaetespedayllAlclylngqykrAyellrka 49 
                 +yk+A+ +   +l        a +++ + ++  l+ +l ++g+y++A e  ++a
  EEA22328.1 763 KYKEAEAMHRQALagynkvlgADHPDTLASLSSLGTVLERQGKYEEAEEMNQQA 816
                 566666666666655555446689999999999**************9988877 PP

  == domain 7  score: 16.5 bits;  conditional E-value: 8.7e-06
                 TT-HHHHHHHHHHHH.........HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCT.SHHHC CS
      ANAPC3   2 qnnyknAiflaerll........aaetespedayllAlclylngqykrAyellrka.klnsk 54 
                 q++y++A+ ++ r+l        a +++ + ++  l+ +ly++g+yk+A    r+a + ++k
  EEA22328.1 845 QGKYEEAEVMYQRVLagykkvlgADHPNTLASLSNLGMVLYRQGKYKEAEAMHRQAlEVREK 906
                 789************88887777799999999999**************9999998666555 PP

  == domain 8  score: -0.4 bits;  conditional E-value: 1.7
                 HHHHHHHHHHHH..HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCT CS
      ANAPC3   5 yknAiflaerlla.aetespedayllAlclylngqykrAyellrka 49 
                 ++ A+  +e++l   ++  + +  +l+ +l ++g+ ++A+e+l+++
  EEA22328.1 939 HRQALAGYEKVLGvDHAMTLMSMRYLSVVLKKQGRRDEALEVLHTY 984
                 4555555566664456666666667788888888888888888776 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.8      0.11        91       4      47 ..     551     602 ..     550     602 .. 0.78
   2 ?    4.8   0.3     0.048        41       3      49 ..     592     646 ..     590     650 .. 0.86
   3 !    8.1   0.2    0.0046       3.9       1      47 [.     674     728 ..     674     737 .. 0.84
   4 !   13.2   1.2   0.00012     0.098       4      53 ..     761     818 ..     758     822 .. 0.79
   5 !   15.3   0.3   2.5e-05     0.021       4      51 ..     845     900 ..     842     906 .. 0.80
   6 !   12.3   0.1   0.00021      0.18       4      54 ..     929     987 ..     928     991 .. 0.79

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.11
      TPR_19   4 egdyaeAlalleqalqedpk.......naearl.lLAeallalgqldeAeal 47 
                 +g+y eA a+ +qal+   k       +  + + +L  +l ++g ++eAea+
  EEA22328.1 551 QGKYKEAEAMHRQALATREKvlgvdhlDTLISMsNLSLVLNKQGKYEEAEAI 602
                 89999**999999999877777777444444447888899999999999986 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.048
      TPR_19   3 aegdyaeAlalleqalqe........dpknaearllLAeallalgqldeAealLd 49 
                 ++g+y+eA a+ +q l++         p+ +    +L  +l  ++ ++eAea+  
  EEA22328.1 592 KQGKYEEAEAIHRQTLAArerilgvdHPNTLTSIGNLGLILNRQKKYKEAEAMNR 646
                 79************99887888888899999999999999999999999999865 PP

  == domain 3  score: 8.1 bits;  conditional E-value: 0.0046
      TPR_19   1 llaegdyaeAlalleqalqe........dpknaearllLAeallalgqldeAeal 47 
                 l+++++y+eA a+ +qal+          p+ +    +L  +l  +g ++eAe +
  EEA22328.1 674 LYMQEKYEEAEAMHRQALAGynkvlgvdHPNTQTSIGNLGLVLDRQGKYEEAEVM 728
                 6899**************99666666667777777779**************986 PP

  == domain 4  score: 13.2 bits;  conditional E-value: 0.00012
      TPR_19   4 egdyaeAlalleqal........qedpknaearllLAeallalgqldeAealLdalpe 53 
                 +g+y eA a+ +qal        ++ p+ ++ +  L  +l  +g ++eAe++ +++++
  EEA22328.1 761 QGKYKEAEAMHRQALagynkvlgADHPDTLASLSSLGTVLERQGKYEEAEEMNQQALA 818
                 9*************9444444444466677777799***************9998876 PP

  == domain 5  score: 15.3 bits;  conditional E-value: 2.5e-05
      TPR_19   4 egdyaeAlalleqal........qedpknaearllLAeallalgqldeAealLdal 51 
                 +g+y+eA  +++++l        ++ p+ ++ + +L  +l+ +g ++eAea+  ++
  EEA22328.1 845 QGKYEEAEVMYQRVLagykkvlgADHPNTLASLSNLGMVLYRQGKYKEAEAMHRQA 900
                 9************994444444455777777777****************986665 PP

  == domain 6  score: 12.3 bits;  conditional E-value: 0.00021
      TPR_19   4 egdyaeAlalleqalqedpk.......naearl.lLAeallalgqldeAealLdalpee 54 
                 +g+y+eA ++ +qal+ + k       +    + +L  +l ++g+ deA ++L ++ + 
  EEA22328.1 929 QGKYEEAEPMHRQALAGYEKvlgvdhaMTLMSMrYLSVVLKKQGRRDEALEVLHTYIQL 987
                 899999999999999998888887544333333578*****************988765 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.2   0.0   2.8e-10   2.4e-07       9     230 ..      80     309 ..      75     318 .. 0.73

  Alignments for each domain:
  == domain 1  score: 30.2 bits;  conditional E-value: 2.8e-10
                 HHHHHCTTTSCSEEEEEEESTTSSHHHHHHHHCCSHCCCCCCBT.EEEEEEEESXXHHHHHHHXXHHHHHCCCTTSSSS-STTS.HHHHHHHHCCCT.T CS
      NB-ARC   9 iekLlekdelqslvvalvGmgGvGKttlakqilnksdevegrFd.svawvvvsktdkseeiletilkeLslseddleekeeves.lkrklvrlLltk.r 104
                  ++ lek++     +alvG gGvGK+ l+ +   +    ++  d  v wv  s+    e+  ++i+ +++      + k++  +   + l++  ++k +
  EEA22328.1  80 LDRILEKGSASPSRIALVGLGGVGKSQLVIEYSYQ--VRDRSPDtWVFWVHTSNAARFEQSYREIADRVKIP-GRKDPKTNIFNlVSEWLHN--EGKgK 173
                 566667777777799***********998765444..44456677899*********************766.4444444333313333444..33369 PP

                 EEEEEEEE-SHHHH.....HHHHC................HTTSEEEEEESBCCCCCCS-S-EEEEEESS--HHHHHHHHHHCCTS-GGCHH..CHHHH CS
      NB-ARC 105 fllvlDDVweeedwdkigvvlpar................enrlrvllTTRdeevanavsatsekievelLekdeawellenkvfekkleekesleeva 187
                  +l+lD + +   + +i +   ++                +   ++++TTR++ va ++ +  + i ve++ + +a +l+e+k  +++ +e+     + 
  EEA22328.1 174 WMLILDSIDDDRFLHEIPLSSRDEsdsripaqplfnylplNAHGSIIITTRSRGVAAKMVEDGDIIAVESMDQIHAQTLFEKKLGKQENQED-----I- 266
                 9*******9999998887665544111111112221122134679***************99*********************999998866.....3. PP

                 HHHHHHCTT-HHHHHHHHHHHC-TCSCCHHHHHHHHHHCTGCC CS
      NB-ARC 188 keivekckGlPlalkvlggllstkktveewkkvleklesklle 230
                  e++   +  Pla++  ++ ++++   ++ k++l +++++   
  EEA22328.1 267 IELIAALEFMPLAIVQAAAYIKQRAPRSSVKQYLTEFQKNDYR 309
                 3455666789999999999999999999999999999877655 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.1       5.1   4.4e+03      13      33 ..     496     516 ..     494     517 .. 0.85
   2 ?   -0.9   0.0       3.2   2.8e+03      20      33 ..     545     558 ..     542     559 .. 0.85
   3 ?    2.2   0.0      0.34   2.9e+02      15      33 ..     582     600 ..     580     601 .. 0.89
   4 ?    1.3   0.0      0.67   5.7e+02      17      33 ..     626     642 ..     618     643 .. 0.87
   5 ?    3.7   0.0      0.12        99      16      33 ..     709     726 ..     694     727 .. 0.85
   6 ?    2.6   0.0      0.26   2.2e+02      14      33 ..     749     768 ..     736     769 .. 0.82
   7 ?    4.7   0.0     0.055        47      16      34 .]     793     811 ..     784     811 .. 0.89
   8 ?    1.0   0.0      0.84   7.2e+02      15      33 ..     834     852 ..     828     852 .. 0.86
   9 !    7.1   0.1    0.0091       7.7      13      33 ..     874     894 ..     862     895 .. 0.80
  10 ?   -0.7   0.0       2.9   2.5e+03      14      33 ..     917     936 ..     911     936 .. 0.85
  11 ?   -0.5   0.0       2.6   2.2e+03      15      34 .]     960     979 ..     959     979 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 5.1
      TPR_17  13 adaynnLAelllknGdlmtAr 33 
                 a ++nn A + l++G+  +A+
  EEA22328.1 496 ALLLNNAALFALSKGNIIEAE 516
                 678999999999***999998 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 3.2
      TPR_17  20 AelllknGdlmtAr 33 
                 + +l ++G++++A+
  EEA22328.1 545 GLVLDRQGKYKEAE 558
                 77899********8 PP

  == domain 3  score: 2.2 bits;  conditional E-value: 0.34
      TPR_17  15 aynnLAelllknGdlmtAr 33 
                 ++ nL  +l k+G++++A+
  EEA22328.1 582 SMSNLSLVLNKQGKYEEAE 600
                 678999************8 PP

  == domain 4  score: 1.3 bits;  conditional E-value: 0.67
      TPR_17  17 nnLAelllknGdlmtAr 33 
                  nL+ +l +++++++A+
  EEA22328.1 626 GNLGLILNRQKKYKEAE 642
                 59**************8 PP

  == domain 5  score: 3.7 bits;  conditional E-value: 0.12
      TPR_17  16 ynnLAelllknGdlmtAr 33 
                   nL+ +l ++G++++A+
  EEA22328.1 709 IGNLGLVLDRQGKYEEAE 726
                 569*************97 PP

  == domain 6  score: 2.6 bits;  conditional E-value: 0.26
      TPR_17  14 daynnLAelllknGdlmtAr 33 
                  ++ nL  +l+++G++++A+
  EEA22328.1 749 TSMDNLSLVLERQGKYKEAE 768
                 678899*************8 PP

  == domain 7  score: 4.7 bits;  conditional E-value: 0.055
      TPR_17  16 ynnLAelllknGdlmtArq 34 
                 +  L+++l+++G++++A++
  EEA22328.1 793 LSSLGTVLERQGKYEEAEE 811
                 6679*************96 PP

  == domain 8  score: 1.0 bits;  conditional E-value: 0.84
      TPR_17  15 aynnLAelllknGdlmtAr 33 
                 ++ nL  +l+++G++++A+
  EEA22328.1 834 SMDNLSLVLERQGKYEEAE 852
                 5669999**********96 PP

  == domain 9  score: 7.1 bits;  conditional E-value: 0.0091
      TPR_17  13 adaynnLAelllknGdlmtAr 33 
                   ++ nL+ +l+++G++++A+
  EEA22328.1 874 LASLSNLGMVLYRQGKYKEAE 894
                 56889***************8 PP

  == domain 10  score: -0.7 bits;  conditional E-value: 2.9
      TPR_17  14 daynnLAelllknGdlmtAr 33 
                  ++ nL  +l  +G++++A+
  EEA22328.1 917 TSMSNLSLVLDGQGKYEEAE 936
                 578899999*********96 PP

  == domain 11  score: -0.5 bits;  conditional E-value: 2.6
      TPR_17  15 aynnLAelllknGdlmtArq 34 
                 ++ +L ++l+k+G+ ++A++
  EEA22328.1 960 SMRYLSVVLKKQGRRDEALE 979
                 68899*********999975 PP

>> DUF1925  Domain of unknown function (DUF1925)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0      0.16   1.4e+02       9      27 ..     553     571 ..     548     581 .. 0.88
   2 ?   -0.1   0.0       1.4   1.2e+03       7      27 ..     593     613 ..     588     623 .. 0.84
   3 ?   -1.4   0.0       3.4   2.9e+03       4      21 ..     632     649 ..     629     660 .. 0.79
   4 ?    1.4   0.0      0.47     4e+02       8      24 ..     678     694 ..     672     709 .. 0.78
   5 ?    0.1   0.0       1.2     1e+03       9      22 ..     721     734 ..     716     754 .. 0.83
   6 ?    0.5   0.0      0.93   7.9e+02       9      22 ..     763     776 ..     759     792 .. 0.82
   7 ?    0.7   0.0       0.8   6.9e+02       9      30 ..     805     826 ..     801     846 .. 0.81
   8 ?    2.9   0.0      0.16   1.4e+02       9      27 ..     847     865 ..     841     878 .. 0.83
   9 !    7.3   0.1    0.0066       5.6       9      30 ..     889     910 ..     881     931 .. 0.79
  10 ?   -0.4   0.0       1.7   1.5e+03       9      25 ..     931     947 ..     927     972 .. 0.80

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.16
     DUF1925   9 kYeesnemhkrmlevskkl 27 
                 kY+e++ mh++ l  ++k+
  EEA22328.1 553 KYKEAEAMHRQALATREKV 571
                 9***********9999886 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 1.4
     DUF1925   7 lvkYeesnemhkrmlevskkl 27 
                   kYee++ +h++ l  ++++
  EEA22328.1 593 QGKYEEAEAIHRQTLAARERI 613
                 569**********99999886 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 3.4
     DUF1925   4 knFlvkYeesnemhkrml 21 
                  n   kY+e++ m ++ l
  EEA22328.1 632 LNRQKKYKEAEAMNRQAL 649
                 57788********98766 PP

  == domain 4  score: 1.4 bits;  conditional E-value: 0.47
     DUF1925   8 vkYeesnemhkrmlevs 24 
                  kYee++ mh++ l   
  EEA22328.1 678 EKYEEAEAMHRQALAGY 694
                 69********9988655 PP

  == domain 5  score: 0.1 bits;  conditional E-value: 1.2
     DUF1925   9 kYeesnemhkrmle 22 
                 kYee++ mh++ l 
  EEA22328.1 721 KYEEAEVMHRQALA 734
                 9********99875 PP

  == domain 6  score: 0.5 bits;  conditional E-value: 0.93
     DUF1925   9 kYeesnemhkrmle 22 
                 kY+e++ mh++ l 
  EEA22328.1 763 KYKEAEAMHRQALA 776
                 9********99876 PP

  == domain 7  score: 0.7 bits;  conditional E-value: 0.8
     DUF1925   9 kYeesnemhkrmlevskklkkl 30 
                 kYee++em ++ l  ++k+  +
  EEA22328.1 805 KYEEAEEMNQQALATREKVLGV 826
                 9************999998655 PP

  == domain 8  score: 2.9 bits;  conditional E-value: 0.16
     DUF1925   9 kYeesnemhkrmlevskkl 27 
                 kYee++ m++r+l   kk+
  EEA22328.1 847 KYEEAEVMYQRVLAGYKKV 865
                 9**********99866665 PP

  == domain 9  score: 7.3 bits;  conditional E-value: 0.0066
     DUF1925   9 kYeesnemhkrmlevskklkkl 30 
                 kY+e++ mh++ lev++k+  +
  EEA22328.1 889 KYKEAEAMHRQALEVREKVLGV 910
                 9****************98665 PP

  == domain 10  score: -0.4 bits;  conditional E-value: 1.7
     DUF1925   9 kYeesnemhkrmlevsk 25 
                 kYee++ mh++ l   +
  EEA22328.1 931 KYEEAEPMHRQALAGYE 947
                 9********99886555 PP

>> DUF3326  Protein of unknown function (DUF3326)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.1   0.7   7.5e-05     0.064      43     164 ..     501     627 ..     488     660 .. 0.69
   2 ?   -1.8   0.0       1.2   1.1e+03      80     124 ..     628     673 ..     621     686 .. 0.79
   3 ?    3.7   0.0     0.027        23      79     126 ..     711     759 ..     700     773 .. 0.84
   4 ?   -0.6   0.0      0.53   4.6e+02      80     123 ..     880     924 ..     816     933 .. 0.82
   5 ?    0.4   0.0      0.28   2.4e+02      79     116 ..     921     959 ..     870    1008 .. 0.66

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 7.5e-05
     DUF3326  43 ngaslywslenvlYvEGyaldrfaageigLqpvrq......nrvglild.kgieeelrlrhlqvadaaratlGlnitevvvtdaplevelrkaesGasw 134
                 n+a +  s+ n++  E +a++ + a + +L ++++      n vgl+ld +g  +e + +h q++ +   +lG++  +++++ ++l++ l+k+ + + +
  EEA22328.1 501 NAALFALSKGNIIEAEKMAVNVMKATKEKLGSEHEstlsstNMVGLVLDrQGKYKEAEAMHRQALATREKVLGVDHLDTLISMSNLSLVLNKQGKYEEA 599
                 5555566777888888888888888888887766444444499******4478899***************************9999888766544444 PP

     DUF3326 135 GtienpdsLlraaekliekagaeAiAvvar 164
                   i++  + l a e+++   + + +  + +
  EEA22328.1 600 EAIHR--QTLAARERILGVDHPNTLTSIGN 627
                 44433..34555555555555555555555 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 1.2
     DUF3326  80 vglildkgie.eelrlrhlqvadaaratlGlnitevvvtdapleve 124
                 +glil++  + +e + ++ q++ +   +lG++  +++++ + l+  
  EEA22328.1 628 LGLILNRQKKyKEAEAMNRQALAGFEKVLGVDHPDTLTSRSILGFG 673
                 7999987654277888999************999998887776655 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.027
     DUF3326  79 rvglild.kgieeelrlrhlqvadaaratlGlnitevvvtdaplevelr 126
                 ++gl+ld +g  ee +++h q++ +   +lG++  +++++  +l++ l+
  EEA22328.1 711 NLGLVLDrQGKYEEAEVMHRQALAGFEKVLGVDHPNTLTSMDNLSLVLE 759
                 579***944788999******************9999998888877665 PP

  == domain 4  score: -0.6 bits;  conditional E-value: 0.53
     DUF3326  80 vglil.dkgieeelrlrhlqvadaaratlGlnitevvvtdaplev 123
                 +g++l  +g  +e + +h q+++    +lG++  +++++ ++l++
  EEA22328.1 880 LGMVLyRQGKYKEAEAMHRQALEVREKVLGVDHPNTLTSMSNLSL 924
                 56665257889999999**************99998888777765 PP

  == domain 5  score: 0.4 bits;  conditional E-value: 0.28
     DUF3326  79 rvglild.kgieeelrlrhlqvadaaratlGlnitevvv 116
                 ++ l+ld +g  ee + +h q++ +   +lG++   +++
  EEA22328.1 921 NLSLVLDgQGKYEEAEPMHRQALAGYEKVLGVDHAMTLM 959
                 334455434455555555555555555555555555555 PP

>> Ses_B  SesB domain on fungal death-pathway protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   3.1   1.4e-06    0.0012       4      27 ..       2      24 ..       1      24 [. 0.91

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 1.4e-06
       Ses_B  4 ssmAsFSGSeNsGlQvGvnsGtin 27
                 s AsF G  N+G+Q+G+nsGti+
  EEA22328.1  2 ASTASFYGT-NHGFQLGYNSGTIG 24
                588999999.************95 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0     1e-05    0.0085       2     163 ..      93     257 ..      92     260 .. 0.77

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 1e-05
                 CEEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-...-HCHHHCCCCTS--SSS-CCHHHHCCSCCCEE.........EEEE-ST CS
       NACHT   2 lvilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgnarsladllfsqlpepaapvsevwavllelperlL.........lilDglD 91 
                  ++l G  G+GK+ L+ +   + +++ ++      vF+++ +   r +++    + +++  + p+++ ++  +++  l    L         lilD++D
  EEA22328.1  93 RIALVGLGGVGKSQLVIEYSYQVRDRSPDT----WVFWVHTSNAARFEQS---YREIADRVKIPGRKDPK--TNIFNLVSEWLhnegkgkwmLILDSID 182
                 58899******************9999776....8***********9977...44455555666555555..55666666666666666677******* PP

                 T-SS-TCH..................HHHHHCTTTTT--EEEEEEECCCHHHHCTTSSCE..EEEE--TCCHHHHHHHHCT CS
       NACHT  92 elvtdlgq.........kekqpvrtlLselirkkllpeasllltvrpralrdleeqleeaivlevegfsesrrkqlvrkyf 163
                 + +  l++         + + p++ l+ + ++       s+++t+r+r++  +++++e+  +++ve++ + ++++l++k +
  EEA22328.1 183 DDRF-LHEiplssrdesDSRIPAQPLF-NYLPL--NAHGSIIITTRSRGV--AAKMVEDGDIIAVESMDQIHAQTLFEKKL 257
                 8654.4445777877755555555555.55555..567899*********..************************99865 PP

>> MIT  MIT (microtubule interacting and transport) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0      0.17   1.4e+02      14      31 ..     548     565 ..     545     574 .. 0.89
   2 ?   -1.2   0.0       2.6   2.2e+03      16      39 ..     634     657 ..     629     669 .. 0.82
   3 ?   -1.7   0.0       3.8   3.2e+03      18      38 ..     678     698 ..     677     712 .. 0.75
   4 !    7.9   0.0    0.0038       3.2       9      39 ..     711     741 ..     707     754 .. 0.83
   5 ?    1.1   0.1      0.48   4.1e+02      14      32 ..     758     776 ..     753     789 .. 0.83
   6 ?    3.1   0.0      0.12     1e+02      10      31 ..     796     817 ..     791     830 .. 0.84
   7 ?    1.7   0.0      0.32   2.7e+02      14      29 ..     842     857 ..     838     868 .. 0.89
   8 ?    1.4   0.1      0.39   3.3e+02      16      37 ..     886     907 ..     876     918 .. 0.83
   9 ?    1.7   0.0      0.32   2.8e+02      13      31 ..     925     943 ..     917     951 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.17
         MIT  14 eDnagnyeeAlelYkeal 31 
                 +D++g+y+eA  + ++al
  EEA22328.1 548 LDRQGKYKEAEAMHRQAL 565
                 7*********99999998 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 2.6
         MIT  16 nagnyeeAlelYkealelLlqalk 39 
                 ++++y+eA  + ++al  + ++l 
  EEA22328.1 634 RQKKYKEAEAMNRQALAGFEKVLG 657
                 5799****9999999999998886 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 3.8
         MIT  18 gnyeeAlelYkealelLlqal 38 
                 ++yeeA  + ++al   +++l
  EEA22328.1 678 EKYEEAEAMHRQALAGYNKVL 698
                 69****999999997666665 PP

  == domain 4  score: 7.9 bits;  conditional E-value: 0.0038
         MIT   9 kkAveeDnagnyeeAlelYkealelLlqalk 39 
                 +    +D++g+yeeA  + ++al  + ++l 
  EEA22328.1 711 NLGLVLDRQGKYEEAEVMHRQALAGFEKVLG 741
                 556789******************9999986 PP

  == domain 5  score: 1.1 bits;  conditional E-value: 0.48
         MIT  14 eDnagnyeeAlelYkeale 32 
                 ++++g+y+eA  + ++al 
  EEA22328.1 758 LERQGKYKEAEAMHRQALA 776
                 7899*********999986 PP

  == domain 6  score: 3.1 bits;  conditional E-value: 0.12
         MIT  10 kAveeDnagnyeeAlelYkeal 31 
                   + ++++g+yeeA e+ ++al
  EEA22328.1 796 LGTVLERQGKYEEAEEMNQQAL 817
                 567899**********999998 PP

  == domain 7  score: 1.7 bits;  conditional E-value: 0.32
         MIT  14 eDnagnyeeAlelYke 29 
                 ++++g+yeeA  +Y+ 
  EEA22328.1 842 LERQGKYEEAEVMYQR 857
                 6899*******99985 PP

  == domain 8  score: 1.4 bits;  conditional E-value: 0.39
         MIT  16 nagnyeeAlelYkealelLlqa 37 
                 ++g+y+eA  + ++ale+  ++
  EEA22328.1 886 RQGKYKEAEAMHRQALEVREKV 907
                 579*************986655 PP

  == domain 9  score: 1.7 bits;  conditional E-value: 0.32
         MIT  13 eeDnagnyeeAlelYkeal 31 
                  +D +g+yeeA  + ++al
  EEA22328.1 925 VLDGQGKYEEAEPMHRQAL 943
                 6899*******99999998 PP

>> TPR_3  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.1       5.4   4.6e+03      14      22 ..     551     559 ..     550     566 .. 0.81
   2 ?   -1.0   0.2       2.2   1.9e+03      14      21 ..     593     600 ..     592     609 .. 0.86
   3 ?   -2.7   0.4       7.5   6.4e+03      14      21 ..     635     642 ..     634     644 .. 0.89
   4 ?    5.7   0.2     0.018        15       8      22 ..     671     685 ..     670     692 .. 0.80
   5 ?    0.1   0.0      0.97   8.3e+02      14      23 ..     719     728 ..     712     734 .. 0.81
   6 ?   -2.6   0.2       6.9   5.9e+03      14      21 ..     761     768 ..     760     774 .. 0.86
   7 ?    3.7   0.0     0.074        63       3      24 ..     792     813 ..     790     821 .. 0.79
   8 ?    5.7   0.0     0.017        15      14      32 ..     845     862 ..     844     864 .. 0.87
   9 ?    6.8   0.0     0.008       6.8       3      22 ..     876     895 ..     874     905 .. 0.84
  10 ?   -1.7   0.0       3.7   3.2e+03      14      21 ..     929     936 ..     929     942 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 5.4
                 TT-HHHHHH CS
       TPR_3  14 kkkyqeAre 22 
                 ++ky eA+ 
  EEA22328.1 551 QGKYKEAEA 559
                 89*****85 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 2.2
                 TT-HHHHH CS
       TPR_3  14 kkkyqeAr 21 
                 ++ky+eA+
  EEA22328.1 593 QGKYEEAE 600
                 8******7 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 7.5
                 TT-HHHHH CS
       TPR_3  14 kkkyqeAr 21 
                 +kky eA+
  EEA22328.1 635 QKKYKEAE 642
                 8******7 PP

  == domain 4  score: 5.7 bits;  conditional E-value: 0.018
                 HHHHHHTT-HHHHHH CS
       TPR_3   8 AaefynkkkyqeAre 22 
                 ++ +y+++ky+eA+ 
  EEA22328.1 671 GFGLYMQEKYEEAEA 685
                 6669*********85 PP

  == domain 5  score: 0.1 bits;  conditional E-value: 0.97
                 TT-HHHHHHH CS
       TPR_3  14 kkkyqeArel 23 
                 ++ky+eA+  
  EEA22328.1 719 QGKYEEAEVM 728
                 8******976 PP

  == domain 6  score: -2.6 bits;  conditional E-value: 6.9
                 TT-HHHHH CS
       TPR_3  14 kkkyqeAr 21 
                 ++ky eA+
  EEA22328.1 761 QGKYKEAE 768
                 8******7 PP

  == domain 7  score: 3.7 bits;  conditional E-value: 0.074
                 HHHHHHHHHHHTT-HHHHHHH. CS
       TPR_3   3 ylysyAaefynkkkyqeArelf 24 
                 +l s++ ++  ++ky+eA+e  
  EEA22328.1 792 SLSSLGTVLERQGKYEEAEEMN 813
                 67788888888********975 PP

  == domain 8  score: 5.7 bits;  conditional E-value: 0.017
                 TT-HHHHHHH..HHHHHHH CS
       TPR_3  14 kkkyqeArelfsYallail 32 
                 ++ky+eA+  ++ ++la +
  EEA22328.1 845 QGKYEEAEVMYQ-RVLAGY 862
                 8***********.999865 PP

  == domain 9  score: 6.8 bits;  conditional E-value: 0.008
                 HHHHHHHHHHHTT-HHHHHH CS
       TPR_3   3 ylysyAaefynkkkyqeAre 22 
                 +l  ++ ++y ++ky eA+ 
  EEA22328.1 876 SLSNLGMVLYRQGKYKEAEA 895
                 67889*************85 PP

  == domain 10  score: -1.7 bits;  conditional E-value: 3.7
                 TT-HHHHH CS
       TPR_3  14 kkkyqeAr 21 
                 ++ky+eA+
  EEA22328.1 929 QGKYEEAE 936
                 89*****7 PP

>> TPR_6  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0       2.9   2.4e+03       6      19 ..     712     725 ..     711     741 .. 0.74
   2 ?   -0.3   0.0       2.6   2.2e+03      11      27 ..     766     782 ..     750     789 .. 0.59
   3 ?   -0.5   0.1         3   2.5e+03       6      21 ..     796     811 ..     795     818 .. 0.85
   4 ?    7.5   0.1    0.0085       7.3       3      30 ..     835     862 ..     833     864 .. 0.87
   5 ?    2.3   0.1      0.37   3.1e+02       5      20 ..     879     894 ..     875     902 .. 0.82
   6 ?   -2.0   0.0         9   7.7e+03      13      27 ..     936     950 ..     927     950 .. 0.75
   7 ?    2.5   0.0      0.33   2.8e+02       6      28 ..     964     986 ..     960     988 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 2.9
                 HHHHHHHHHHHHHH CS
       TPR_6   6 lalsyrklgdtdkA 19 
                 l+l + ++g++++A
  EEA22328.1 712 LGLVLDRQGKYEEA 725
                 77888888888877 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 2.6
                 HHHHHHHHHHHHHHHHH CS
       TPR_6  11 rklgdtdkAlealerli 27 
                 ++   +++Al+ +++++
  EEA22328.1 766 EAEAMHRQALAGYNKVL 782
                 23236667777777665 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 3
                 HHHHHHHHHHHHHHHH CS
       TPR_6   6 lalsyrklgdtdkAle 21 
                 l+  ++++g++++A e
  EEA22328.1 796 LGTVLERQGKYEEAEE 811
                 688899999****976 PP

  == domain 4  score: 7.5 bits;  conditional E-value: 0.0085
                 HHHHHHHHHHHHHHHHHHHHHHHHHHH- CS
       TPR_6   3 lyklalsyrklgdtdkAlealerlikeY 30 
                 + +l l ++++g++++A  +++r++  Y
  EEA22328.1 835 MDNLSLVLERQGKYEEAEVMYQRVLAGY 862
                 567889999***************9765 PP

  == domain 5  score: 2.3 bits;  conditional E-value: 0.37
                 HHHHHHHHHHHHHHHH CS
       TPR_6   5 klalsyrklgdtdkAl 20 
                 +l++ ++++g++ +A 
  EEA22328.1 879 NLGMVLYRQGKYKEAE 894
                 7999999999999985 PP

  == domain 6  score: -2.0 bits;  conditional E-value: 9
                 HHHHHHHHHHHHHHH CS
       TPR_6  13 lgdtdkAlealerli 27 
                    +++Al+ +e+++
  EEA22328.1 936 EPMHRQALAGYEKVL 950
                 457899999999985 PP

  == domain 7  score: 2.5 bits;  conditional E-value: 0.33
                 HHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   6 lalsyrklgdtdkAlealerlik 28 
                 l   ++k+g+ d+Ale l   i+
  EEA22328.1 964 LSVVLKKQGRRDEALEVLHTYIQ 986
                 556778999********998886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1026 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       679  (0.0378716); expected 358.6 (0.02)
Passed bias filter:                      492  (0.0274416); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                        23  (0.00128284); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              21  [number of targets reported over threshold]
# CPU time: 0.93u 0.33s 00:00:01.26 Elapsed: 00:00:00.56
# Mc/sec: 5480.50
//
Query:       EEA22329.1  [L=327]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.3e-22   78.9   0.1    1.5e-17   63.7   0.1    2.2  2  adh_short        short chain dehydrogenase
    3.3e-14   53.0   0.0    2.8e-10   40.2   0.0    2.2  2  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    1.6e-06   28.2   0.0    2.5e-06   27.5   0.0    1.3  1  KR               KR domain
     0.0079   15.4   0.0      0.012   14.7   0.0    1.4  1  Polysacc_synt_2  Polysaccharide biosynthesis protein
  ------ inclusion threshold ------
       0.11   11.8   0.0       0.21   10.9   0.0    1.5  2  GDP_Man_Dehyd    GDP-mannose 4,6 dehydratase


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.7   0.1   4.3e-21   1.5e-17       2     125 ..      20     152 ..      19     172 .. 0.85
   2 !   13.1   0.0   1.3e-05     0.047     144     188 ..     196     240 ..     191     243 .. 0.90

  Alignments for each domain:
  == domain 1  score: 63.7 bits;  conditional E-value: 4.3e-21
                 EEEEESTTSHHHHHHHHHHHHTT-.EEEEEESCHHHHHHHHHHHHHT....TSE.....EEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS-- CS
   adh_short   2 vvlvtGassGIGraiakelakeGa.kvvvvdrseekleevakelkee....gak.....alaiqvDvtdreevealvekavkklgkldvLvnNAGitgs 90 
                 +vlvtG+++GIG + a+++++  + ++++++r++++ +e +  l+++    + +     + ++ +D+ d+++v ++ e+++k+   ldvLv NAG+   
  EEA22329.1  20 TVLVTGGTNGIGFEAARQFLTFKVpRIIITARNASRGAESVRALRADpevaK-NnpnaiIDVFDLDLDDYKSVIKFSEHVKKEAPALDVLVCNAGM--A 115
                 89*****************9977626666**************999876541.134555889999999****************************..6 PP

                 SSGGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHH..H CS
   adh_short  91 gpfselseeewervievNltgvflltravlpaml..k 125
                 +++ ++s +  e++++vN  + fll+ ++lp +   +
  EEA22329.1 116 QMVFKMSVTGHEQIMQVNCWSNFLLVLELLPVLQatA 152
                 88889**************************988663 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 1.3e-05
                 TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHH CS
   adh_short 144 agvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmak 188
                 + +  Y  sK  v+++++ la  + ++++  n+ +PG+v T++ +
  EEA22329.1 196 KKMKRYNDSKLVVNAFIHHLATIVPSSEVIMNNFCPGAVPTNFEQ 240
                 5678899**********************************9876 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.2   0.0   7.8e-14   2.8e-10       3     134 ..      27     169 ..      25     179 .. 0.83
   2 !   11.0   0.0   6.3e-05      0.23     126     183 ..     186     243 ..     168     270 .. 0.86

  Alignments for each domain:
  == domain 1  score: 40.2 bits;  conditional E-value: 7.8e-14
                   TTSHHHHHHHHHHHTT-.EEEEEESSGGH.HHHHHHHHHHTT......SEE...EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GG CS
  adh_short_C2   3 asgIGraiAkalaeeGa.evvltdlneea.kkrveelaeelg......aev...lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfl 88 
                    +gIG+++A+++      ++++t +n ++ +++v++l ++ +      +++   + +D  d ++v ++ e+v+++   lD+lv nag+a+     + 
    EEA22329.1  27 TNGIGFEAARQFLTFKVpRIIITARNASRgAESVRALRADPEvaknnpNAIidvFDLDLDDYKSVIKFSEHVKKEAPALDVLVCNAGMAQM----VF 119
                   58**********9988747999999999999***99988755433322332577*************************************....** PP

                   GH-HHHHHHHHHHHTHHHHHHHHHHHHHCTSC....CEEEEEEEGGGTSB CS
  adh_short_C2  89 etsreefdraldvnlyslfllakaalplmkeg....gsivnlssvgaerv 134
                   ++s  + +++++vn+ s fll+ ++lp+++++    g+  +l++vg+++ 
    EEA22329.1 120 KMSVTGHEQIMQVNCWSNFLLVLELLPVLQATaarkGQPSHLTFVGSNMQ 169
                   ***************************77765445577777777776665 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 6.3e-05
                   EEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGST CS
  adh_short_C2 126 lssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgik 183
                   l+++  e++ ++ + y+ +K  ++a+++ lA  + + ++  N  +pg++ T+  ++++
    EEA22329.1 186 LAFFDDEQAAKKMKRYNDSKLVVNAFIHHLATIVPSSEVIMNNFCPGAVPTNFEQHMP 243
                   67788899999****************************************9877665 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.5   0.0   7.1e-10   2.5e-06       2      94 ..      20     117 ..      19     135 .. 0.79

  Alignments for each domain:
  == domain 1  score: 27.5 bits;  conditional E-value: 7.1e-10
                 EEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHH...HHHHT..T-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE------- CS
          KR   2 tylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskalia...eleal..gaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrd 94 
                 t+l+tGG+ g+G e ar+ +     ++++++R+a+  ++s + ++   e++++  +a ++v+++D+ d ++v +  e++k+e+p++   +  Ag+++ 
  EEA22329.1  20 TVLVTGGTNGIGFEAARQFLTFKVPRIIITARNASRGAESVRALRadpEVAKNnpNAIIDVFDLDLDDYKSVIKFSEHVKKEAPALDVLVCNAGMAQM 117
                 78*******************************8555555443331112333224779********************************99999874 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   3.4e-06     0.012       1      65 [.      21      82 ..      21     137 .. 0.65

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 3.4e-06
                     EEEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH......-TTEEEE....E--TT- CS
  Polysacc_synt_2  1 vlvtGagGsiGselvrqilkkkpkkiillerdElklyeiekeleeelkkkklkveivpvigdvrd 65
                     vlvtG++  iG e  rq+l++k+ +ii+  r+  +  e  + l+++    ++  +  + i dv d
       EEA22329.1 21 VLVTGGTNGIGFEAARQFLTFKVPRIIITARNASRGAESVRALRAD---PEVAKNNPNAIIDVFD 82
                     89**************************999877766655555322...2233333445555544 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0     6e-05      0.21       1      75 [.      22      99 ..      22     144 .. 0.88
   2 ?   -3.2   0.0       1.2   4.2e+03      82      98 ..     251     267 ..     249     269 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 6e-05
                   EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGC.C..EEEEE--TT-HHHHHHHHHHHT CS
  GDP_Man_Dehyd  1 LiTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeelee.n..lklhkgDltDssslerllaevq 75
                   L+TG++  iG   a+++l+ +   ++i+ r++s  ++++++l+ dp++ +++ n  + ++  Dl D +s+++  ++v+
     EEA22329.1 22 LVTGGTNGIGFEAARQFLTFKVPRIIITARNASRGAESVRALRADPEVAKNNpNaiIDVFDLDLDDYKSVIKFSEHVK 99
                   9******************999999999999999***********99865543234779999******9999877665 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 1.2
                    --S---HHHHTTSHHHH CS
  GDP_Man_Dehyd  82 LAAqshVdvsfekPeyt 98 
                    LAA++ +++s++++ +t
     EEA22329.1 251 LAAKKSIGRSIQEAGRT 267
                    9**********998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (327 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       502  (0.0279993); expected 358.6 (0.02)
Passed bias filter:                      470  (0.0262145); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.45
# Mc/sec: 2185.34
//
Query:       EEA22330.1  [L=238]
Description: hypothetical protein PMAA_061090 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (238 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       335  (0.0186848); expected 358.6 (0.02)
Passed bias filter:                      306  (0.0170673); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 1681.10
//
Query:       EEA22331.1  [L=455]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.6e-36  123.8  24.8    1.1e-24   87.0   7.0    2.1  2  MFS_1     Major Facilitator Superfamily
    7.9e-07   27.7   4.8    1.9e-05   23.2   4.8    2.6  1  OATP      Organic Anion Transporter Polypeptide (OATP) family
    5.5e-05   21.9  13.1     0.0058   15.2   9.7    2.3  2  MFS_2     MFS/sugar transport protein
  ------ inclusion threshold ------
      0.011   14.1  11.3     0.0092   14.4   8.7    1.9  2  MFS_3     Transmembrane secretion effector


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.0   7.0   2.5e-28   1.1e-24       1     186 [.      26     215 ..      23     235 .. 0.83
   2 !   42.2  10.1   1.1e-14   4.9e-11       3     158 ..     275     454 ..     271     455 .] 0.90

  Alignments for each domain:
  == domain 1  score: 87.0 bits;  conditional E-value: 2.5e-28
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispse....igllltlyalgaavaslplGrlsdrfGrrr.vlllglllfalglllllfa.sslwlllvlrv 93 
                 +++a+f   + ++++ p+l  +l e l+++ s     i+l+l++ al+++v  +++G+++dr+++r+  ll++l + ++g ++++ a +s+ +l+ +r+
  EEA22331.1  26 IAIALFTENFLFTFIVPILDYMLEERLNVDRSNaqhvISLVLSVHALVCVVVGPLTGHIADRISSRKgALLVSLSCELVG-TIIVAAaPSVAILICGRI 123
                 4667777777778888888866666788666665566999****************************************.66663426666******* PP

       MFS_1  94 lqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspke 186
                 + ++g+ a++ +g+a +ad +  e+ ++ +g +s+ ++ G +lgp ++g+l+ ++g+ ++ + +ai+ l++ + + l++ e+p+e k ++ + 
  EEA22331.1 124 ILAIGGNAAWIIGLATLADTVGTENSAQTLGTISVIYNSGLLLGPTVSGWLLGLAGY-WPTWSAAIAVLVVDMAMRLVIIEKPKEQKDVEATA 215
                 ****************************************************88885.88899988888887766677777776666665544 PP

  == domain 2  score: 42.2 bits;  conditional E-value: 1.1e-14
       MFS_1   3 laaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfass................l 85 
                  +++ s+l  + l ++lpl++ +d+ ++ ++ ++++ l  l ++++   +G+l dr+G +    +g+ll++l l+ll   ++                +
  EEA22331.1 275 ACHMTSSLVVTSLDTTLPLHVIRDFEWNIAQTSFMFLLIQLPQLALGTYTGWLKDRHGTKVATGVGYLLTGLLLWLLGA-PGhdgfsfigsgqkgqiiY 372
                 688899999999*******999***************************************************777773.2233555666677888885 PP

       MFS_1  86 w.lllvlrvlqGlgagalfpagaaliadwfpke........ergraigllsagfslGailgpllggllasslgWravfyila 158
                   +ll+l +  +l+ g+++  + ++i+++ +++          +ra++l + ++++G + gpll+g l++++g+ ++ +i++
  EEA22331.1 373 SsTLLALGFARSLTIGTGVIEITSVIREIQTEKpgifgpngGYSRAYSLTNFSWNVGLLTGPLLSGSLVQAVGYYYMNFIFG 454
                 559**************************999999999999*********************************99887776 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.2   4.8   4.2e-09   1.9e-05     131     351 ..     114     325 ..      13     353 .. 0.75

  Alignments for each domain:
  == domain 1  score: 23.2 bits;  conditional E-value: 4.2e-09
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 131 lvllfflaqlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllklyvdidseisltpkdprWvgaWWlgflilgvlllla 229
                  v +++++ ++l+iG+ + + +G++ + D v ++ns+  lg+++++   G  lG ++++ ll l   +          p      W   + + v+ + +
  EEA22331.1 114 SVAILICGRIILAIGGNAAWIIGLATLADTVGTENSAQTLGTISVIYNSGLLLGPTVSGWLLGLAGYW----------PT-----WSAAIAVLVVDMAM 197
                 3459*********************************************************9966444..........33.....45555555555666 PP

                 xxxxxxxxxx...xxxxxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 230 aiplffFPke...lpkkkeerakkkseeesae........kkeekkkkeksksseeeelkslkdfpkalkrllknpifllvilssvfeillvaGfitFl 317
                  ++++  Pke    + +++++ +++s     e        ++++ + +e+++++  ++++++   ++ ++ +l++p  l+ + + ++ +l+v+ + t l
  EEA22331.1 198 RLVIIEKPKEqkdVEATAADAGTNNSLD---EttpllqppTANTGNIQESASRE--DTVQQTDGSLNFYRIVLSHPRALTAMACHMTSSLVVTSLDTTL 291
                 6666667777333333333333333333...13344555433333333333333..478999999********************************** PP

                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 318 pkylEtqFslsaseAnlltGvvvipgaalGillg 351
                 p  + + F+ + ++ ++++ ++ +p  alG+  g
  EEA22331.1 292 PLHVIRDFEWNIAQTSFMFLLIQLPQLALGTYTG 325
                 ******************************9865 PP

>> MFS_2  MFS/sugar transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   9.7   1.3e-06    0.0058     247     387 ..      44     185 ..      18     202 .. 0.77
   2 !    7.8   0.1   0.00024       1.1     200     305 ..     245     350 ..     235     402 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1.3e-06
       MFS_2 247 llYyltyvlg.ngsaas.vfllvvtisal...lgiplwqplakrlgkkntyllgalltivllvlvlllqpsnlllflvllviagfgvgvaallpwsmla 340
                 l Y l+  l+ ++s+a+ v++lv+ + al   ++ pl   +a r++ ++ +ll +l++ + +++++++ + ++++++   +i  +g  +a+++  ++la
  EEA22331.1  44 LDYMLEERLNvDRSNAQhVISLVLSVHALvcvVVGPLTGHIADRISSRKGALLVSLSCELVGTIIVAA-APSVAILICGRIILAIGGNAAWIIGLATLA 141
                 4555555555555555413334445555555577789999*******999999999999999999999.99999999********************** PP

       MFS_2 341 dvvDygelktGkrregvffavlsfisklatgiglgvsgllLsafgy....r 387
                 d+v       G+ +   + ++ s i + +  +g  vsg+lL+++gy    +
  EEA22331.1 142 DTV-------GTENSAQTLGTISVIYNSGLLLGPTVSGWLLGLAGYwptwS 185
                 **9.......888999******************************64332 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.00024
       MFS_2 200 rkkekteqkeklslleqlkevfrnraflillllfllaalalgvl.nglllYyltyvlgngsaasvfllvvtisallgiplwqplakrlgkkntyllgal 297
                 +++e+t q++ +sl +  + v++++ +l+ +++ ++ +l ++ l  +l l++++++  n ++ s+++l++ +++l+      +l+ r g k ++ +g+l
  EEA22331.1 245 ASREDTVQQTDGSL-NFYRIVLSHPRALTAMACHMTSSLVVTSLdTTLPLHVIRDFEWNIAQTSFMFLLIQLPQLALGTYTGWLKDRHGTKVATGVGYL 342
                 56677777777664.57899***************99998766515666778888888***************************************** PP

       MFS_2 298 ltivllvl 305
                 lt +ll l
  EEA22331.1 343 LTGLLLWL 350
                 99988765 PP

>> MFS_3  Transmembrane secretion effector
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   8.7   2.1e-06    0.0092      40     186 ..      56     197 ..      51     219 .. 0.77
   2 ?   -0.7   0.0     0.076   3.4e+02     140     169 ..     418     447 ..     414     453 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 2.1e-06
       MFS_3  40 isasplmvAlvqaaatLPifllsilaGalaDnfdrRkvllavqlllalvsvlltvlaalgllspwlllaltlligiGaalndPaWqAsvgelvkrrdvp 138
                  s ++  + lv    +L  +++  l+G +aD ++ Rk  l v l   lv ++++        s+ +l+   ++++iG         A++ + v  ++  
  EEA22331.1  56 RSNAQHVISLVLSVHALVCVVVGPLTGHIADRISSRKGALLVSLSCELVGTIIVAA----APSVAILICGRIILAIGGNAAWIIGLATLADTVGTENSA 150
                 5778889999*99*******************999986665555555555444333....45788899999999999987777778************9 PP

       MFS_3 139 aAvaLnsvginiaRsvGPAlgGvlvaavGaalafavnalsylalival 186
                 +     sv +n     GP ++G l+ ++G + +++++  + l++ +a+
  EEA22331.1 151 QTLGTISVIYNSGLLLGPTVSGWLLGLAGYWPTWSAAI-AVLVVDMAM 197
                 9999**************************99997654.333333333 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.076
       MFS_3 140 AvaLnsvginiaRsvGPAlgGvlvaavGaa 169
                 A  L+   +n+    GP l+G lv avG  
  EEA22331.1 418 AYSLTNFSWNVGLLTGPLLSGSLVQAVGYY 447
                 778999999******************975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (455 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       518  (0.0288917); expected 358.6 (0.02)
Passed bias filter:                      294  (0.016398); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.42
# Mc/sec: 3291.07
//
Query:       EEA22332.1  [L=274]
Description: aspergillopepsin-2 precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.8e-69  233.4  17.7    2.4e-69  233.0  17.7    1.2  1  Peptidase_A4  Peptidase A4 family
  ------ inclusion threshold ------
      0.016   15.1   0.2       0.04   13.7   0.2    1.7  1  DHFR_2        R67 dihydrofolate reductase
      0.073   13.0   1.1        2.8    7.9   0.1    2.4  2  DUF1869       Domain of unknown function (DUF1869)
       0.71   10.0   2.3       0.38   10.9   0.3    1.5  2  UPF0561       Uncharacterised protein family UPF0561


Domain annotation for each model (and alignments):
>> Peptidase_A4  Peptidase A4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  233.0  17.7   5.4e-73   2.4e-69       1     209 []      70     273 ..      70     273 .. 0.96

  Alignments for each domain:
  == domain 1  score: 233.0 bits;  conditional E-value: 5.4e-73
  Peptidase_A4   1 snwaGavlespesgftsVtgtftvPklslpsggdesaeysasawVGiDGaadtcssallqaGvdftvdsnGeqsydawyewyPayavdfsg.lavsa 96 
                   snwaGavl +  sg+tsVtg+f+vP+++lp+ggd++++y+a+awVGiDG  dtc++a+lq+Gv+++++  G+ + +awyew+Pa++ ++ + l++++
    EEA22332.1  70 SNWAGAVLVG--SGYTSVTGSFVVPSVTLPAGGDRTKQYCAAAWVGIDG--DTCGTAILQTGVNICIQ-YGQITNTAWYEWFPASQSYWPSdLSINT 161
                   7*********..*************************************..*****************.**************666666655***** PP

  Peptidase_A4  97 GDsvtvtvtatsatsgtvtieNlstgqsvtktlsapssklcgqsAeWivEdfesgg.lvplanFg.tvtFtdasattsdgksvglsgatiidieqng 191
                   GD++t+tvta + t gt+t++N+stgqsv+ t+s+++++lc+++AeWi+Ed++sgg l+++a+Fg + tFt+a+a +++  +v+++gati+di qn+
    EEA22332.1 162 GDTITATVTADGLTGGTATVTNESTGQSVSSTFSGQTASLCQTNAEWIMEDLSSGGgLLNFADFGsDFTFTGATALSNGA-TVDTTGATIMDIYQNK 257
                   *****************************************************9999********89********88888.*************995 PP

  Peptidase_A4 192 tvltsvevsgdsevtvsy 209
                    vlts+++sg++ v++sy
    EEA22332.1 258 -VLTSTTASGST-VVISY 273
                   .*******9999.*9998 PP

>> DHFR_2  R67 dihydrofolate reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.2     9e-06      0.04      10      42 ..      83     114 ..      79     128 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 9e-06
      DHFR_2  10 apvaGrfalpsnatfglGdrvrkksGaawqGqi 42 
                 ++v+G f++ps +  + Gdr ++   aaw G i
  EEA22332.1  83 TSVTGSFVVPSVTLPAGGDRTKQYCAAAWVG-I 114
                 79***************************98.4 PP

>> DUF1869  Domain of unknown function (DUF1869)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   0.1   0.00063       2.8       6      34 ..     178     206 ..     175     214 .. 0.75
   2 ?    3.3   0.1     0.017        75       9      32 ..     234     257 ..     227     265 .. 0.79

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.00063
                 EEEEEETTT--EEEEEE--SCGGC-HHHH CS
     DUF1869   6 llTvTNknNGVSVDkefeslaeLkdpeva 34 
                 + TvTN++ G SV  +f+  ++ + +++a
  EEA22332.1 178 TATVTNESTGQSVSSTFSGQTASLCQTNA 206
                 57**************9976655555555 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.017
                 EEETTT--EEEEEE--SCGGC-HH CS
     DUF1869   9 vTNknNGVSVDkefeslaeLkdpe 32 
                  T  +NG  VD + ++++++ +++
  EEA22332.1 234 ATALSNGATVDTTGATIMDIYQNK 257
                 57889**********999987655 PP

>> UPF0561  Uncharacterised protein family UPF0561
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.3   8.4e-05      0.38      45      92 ..      24      71 ..      19      79 .. 0.88
   2 ?   -3.9   0.1       3.2   1.4e+04      80      92 ..     181     193 ..     170     201 .. 0.53

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 8.4e-05
     UPF0561 45 ekqrrrhtttprrprrpdlqvylprsrdgsepgsnaeaeesnesssst 92
                e+  rr ++   r  rp+ q ++ +  + se+ s++++e ++e  ss 
  EEA22332.1 24 ENLARREANRVARRARPNQQTHTNQRINASEELSTTDSETFAEVYSSN 71
                6667888999999999**************************998875 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 3.2
     UPF0561  80 aeaeesnesssst 92 
                    e  ++s sst
  EEA22332.1 181 VTNESTGQSVSST 193
                 2334455555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (274 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       565  (0.0315132); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.46u 0.29s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 1851.24
//
Query:       EEA22333.1  [L=1027]
Description: dihydrolipoyl dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.2e-43  146.7   0.1    1.3e-42  146.1   0.1    1.2  1  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    1.8e-16   60.4   1.8    1.7e-15   57.4   0.1    2.6  2  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
    4.2e-16   59.2   0.0      8e-16   58.3   0.0    1.5  1  Pyr_redox_dim   Pyridine nucleotide-disulphide oxidoreductase
    2.9e-05   23.5   0.6    0.00076   18.8   0.0    2.3  2  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
    3.3e-05   22.8   4.7       0.15   10.7   0.1    3.2  3  HI0933_like     HI0933-like protein
    0.00033   19.8   1.9       0.35    9.9   0.0    3.3  3  Lycopene_cycl   Lycopene cyclase protein
    0.00043   19.2   0.2    0.00087   18.2   0.2    1.4  1  Fungal_trans_2  Fungal specific transcription factor domain
     0.0018   18.7   0.3       0.58   10.6   0.1    2.5  2  NAD_binding_7   Putative NAD(P)-binding
     0.0026   16.9   3.8       0.31   10.1   0.2    2.8  2  GIDA            Glucose inhibited division protein A
      0.004   16.4   0.2       0.04   13.1   0.0    2.4  2  Thi4            Thi4 family
     0.0056   16.0   0.7        1.5    8.0   0.1    2.3  2  FAD_binding_3   FAD binding domain
  ------ inclusion threshold ------
      0.018   15.3   1.2        1.8    8.9   0.1    3.1  2  NAD_binding_8   NAD(P)-binding Rossmann-like domain
      0.024   15.1   0.0       0.41   11.2   0.0    2.7  2  XdhC_C          XdhC Rossmann domain
      0.036   13.4   0.0        0.1   12.0   0.0    1.8  1  2-Hacid_dh_C    D-isomer specific 2-hydroxyacid dehydrogenase
       0.18   11.7   2.4       0.23   11.3   0.1    2.4  3  3HCDH_N         3-hydroxyacyl-CoA dehydrogenase, NAD binding 
       0.37   10.1   2.0       0.36   10.1   0.4    1.7  2  AlaDh_PNT_C     Alanine dehydrogenase/PNT, C-terminal domain
       0.65    9.5   3.5        3.9    7.0   0.1    2.8  3  DAO             FAD dependent oxidoreductase


Domain annotation for each model (and alignments):
>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  146.1   0.1   1.2e-45   1.3e-42       1     286 [.     544     867 ..     544     878 .. 0.83

  Alignments for each domain:
  == domain 1  score: 146.1 bits;  conditional E-value: 1.2e-45
                  CSEEEE--SHHHHHHHHHHHHHTS-EEEEE...TTHCHHHCSHHHHCHHHHHHHHHHHHH...................................HHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxx...................................xxx RF
  Pyr_redox_2   1 kdvvviGgGpAGlaaaltlaqagakvtlve...legtclnggcllskallgvaedaeias...................................evv 60 
                  +d+++iGgGp    a  +la+ag+ v+++e    +g+c+++gc++skall+  e+ e a+                                      
   EEA22333.1 544 FDIIIIGGGPVTSFAESRLAKAGLSVAVIEhelYGGECHFFGCIPSKALLRPVEAFEAAKaidgareaigknkldvaavferrdrfvdlwddktwI-- 639
                  589**************************999*************************999******999999999987777777777666653221.. PP

                  HCHHHHCCCCHCCTCEEEEESCEEEEETEEEC....TCEEEEEE...SEEEE---EEE-BCTCTTC.TTBEECCSECHHHHHHCCSS-TSEEEEES-S CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  61 kklnqgielllgeevvkidpgkkkvklekkke....gdeekiay...dklvlAtGssprdlgipGvaenvgklvrtldsaealklkllpkrivvvGgG 151
                   ++++g    + + +++ + g kkv      +    g+++k+      ++++AtGs+   + ipG  e   ++ + + + +a+  +  p+++++ G+G
   EEA22333.1 640 -SISNGSSGATLVRGFGRIAGMKKV------SvqphGETQKYHLdanIAIIIATGSTHSVPAIPGI-ESLEEGTELWSNRDAVAANIAPEHLIILGAG 729
                  .222222222222344444555555......355334444444433558*****************.444455588********************** PP

                  HHHHHHHHHHHHHT-EEEEEESSSSSSTTS-HHHHHHHHHHHHHTTEEEEESCEEEEEEETTE.EEEEEETTSCEEEESEEEE-S-EEES-HHCS.HC CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xx RF
  Pyr_redox_2 152 yiGvElAaalaklgkevtlveardrllraldkelsaaleealekeGvevklgtsvkeidgnge.klevvledgeeidadlvvvavGvrpstelle.ek 247
                  ++G+E+A +++ +g++vtl+    ++l++++ ++++++++ le++Gv +kl ++v +i+++   +l+vvl++ge+i  + ++ a+G+rp+t  l+ ++
   EEA22333.1 730 PVGSEMATFYSAIGSKVTLISSTAEILPMVEGAAAKIVRKSLEASGVSIKLSSRVDKIEKHAAnSLTVVLSSGETISGSVLLNATGRRPRTFDLGlDS 827
                  *************************************************************999999******************************* PP

                  CT-EEEETTEEE--TTSBE.....SSTTEEE-GGGCTECCSS-- CS
                  xxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 248 lglelderggivvdeflrt.....nvpgiyaiGDvaggkggpel 286
                  +gl+  e+  +++d++l++     + p ++aiGDv    g   +
   EEA22333.1 828 IGLTG-EGQPLKTDSRLAVptaqgTEPWLFAIGDVN---GLAPT 867
                  ***76.99999******65445558**********9...33333 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.1      0.42   4.4e+02       2      30 ..     546     574 ..     545     576 .. 0.90
   2 !   57.4   0.1   1.6e-18   1.7e-15       1      79 [.     722     800 ..     722     803 .. 0.94

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.42
                 EEEECSSHHHHHHHHHHHHTTSEEEEEES CS
   Pyr_redox   2 vvvvGgGyiglElAgalaelgkkVtvver 30 
                 ++++GgG +   + + la+ g +V v+e 
  EEA22333.1 546 IIIIGGGPVTSFAESRLAKAGLSVAVIEH 574
                 89*******99999999999999999986 PP

  == domain 2  score: 57.4 bits;  conditional E-value: 1.6e-18
                 EEEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSSTTSSHHHHHHHHHHHHHTTEEEECSEEEEEEEEETTS.EEEEEEE CS
   Pyr_redox   1 kvvvvGgGyiglElAgalaelgkkVtvversdkllrllDeeaskilqeklekngievllntkveeiegsedg.vesvklk 79 
                 +++++G+G +g E+A++++++g+kVt++    ++l++ + +a+ki++++le+ g+ + l+++v +ie+++ + ++ v+l+
  EEA22333.1 722 HLIILGAGPVGSEMATFYSAIGSKVTLISSTAEILPMVEGAAAKIVRKSLEASGVSIKLSSRVDKIEKHAANsLT-VVLS 800
                 789******************************************************************998666.7665 PP

>> Pyr_redox_dim  Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.3   0.0   7.6e-19     8e-16       2     107 ..     914    1019 ..     913    1022 .. 0.94

  Alignments for each domain:
  == domain 1  score: 58.3 bits;  conditional E-value: 7.6e-19
                     EEEEESSSEEEEEES-HHHHHHHHSGEEEEEEEEECGHHHCHTTHTEEEEEEEEETTTTBEEEEEEECTTHHHHHHHHHHHHHTTSBHHHHHTS CS
  Pyr_redox_dim    2 ptvvftdpevasvGlteeeAkaagieikvgkfpfkangralayaetkgfvKlvadaktgkvlGahivGpgageliqelavaikagltvedladt 95  
                     ++v+ft+p++++vG t ++A+ ag++++ + ++f+  g  l+ +++ g+++ v+++ t+k++Ga++++ + +e +++ +vai +glt +++ + 
     EEA22333.1  914 AQVIFTEPNIGTVGHTFASAQSAGLKVRAVDSDFSIAGAWLYGDRQPGWARWVIEEGTDKLVGATFCCVEGSEFVNASQVAILQGLTLKEMVHV 1007
                     689*******************************87777777777************************************************* PP

                     BSSSSSTGGGGH CS
  Pyr_redox_dim   96 ihihPtlsealk 107 
                     + + Pt  e ++
     EEA22333.1 1008 VPPFPTRGEIWT 1019
                     ******998766 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.3     0.076        80       1      30 [.     547     575 ..     547     582 .. 0.90
   2 !   18.8   0.0   7.2e-07   0.00076     117     271 ..     670     820 ..     651     842 .. 0.74

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.076
  Pyr_redox_3   1 iIiGaGPaGlaaaielkkagledylilEkg 30 
                  iIiG+GP    a   l kagl ++ ++E +
   EEA22333.1 547 IIIGGGPVTSFAESRLAKAGL-SVAVIEHE 575
                  8*******999999*******.799**986 PP

  == domain 2  score: 18.8 bits;  conditional E-value: 7.2e-07
  Pyr_redox_3 117 etsketyeAk.kviiAtGe.fdkPnklnipGeek.lvkhyskvkefhkyagqkvvViGgknSavDaAlelvrkgaeVtvvtrgseiekeesdpsyslk 211
                  et+k  + A+  +iiAtG   + P  ++i+  e+ +   +  +  ++++a +++++ G++  + ++A+   + g++Vt++ +++ei  +    +    
   EEA22333.1 670 ETQKYHLDANiAIIIATGStHSVPAIPGIESLEEgTELWSNRDAVAANIAPEHLIILGAGPVGSEMATFYSAIGSKVTLISSTAEILPMV---EGAAA 764
                  57777777763599****72455666666665543455566666778999*********************************9988874...45555 PP

  Pyr_redox_3 212 pdienrleelvkeekikvlfnaevkeikek.eeeykvktedgkkvevkddvvlatGykpdl 271
                   ++++ le+    + + +   ++v++i+++  ++ +v  ++g+++ + +  + atG +p +
   EEA22333.1 765 KIVRKSLEA----SGVSIKLSSRVDKIEKHaANSLTVVLSSGETI-SGSVLLNATGRRPRT 820
                  666666655....4488999999****976156678888998765.457777789988875 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.7   0.1   0.00014      0.15       1      32 [.     544     575 ..     544     580 .. 0.94
   2 ?    2.6   0.1     0.041        43       2      35 ..     722     755 ..     721     764 .. 0.89
   3 !    9.8   0.2   0.00027      0.29     114     163 ..     766     815 ..     759     841 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00014
                  -SEEEE--SHHHHHHHHHHHHTT--EEEE-SS CS
  HI0933_like   1 kdviviGgGaAGlmaAisaakrgkrVllleka 32 
                  +d+i+iGgG+   +a  ++ak+g +V+++e++
   EEA22333.1 544 FDIIIIGGGPVTSFAESRLAKAGLSVAVIEHE 575
                  589***************************96 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.041
                  SEEEE--SHHHHHHHHHHHHTT--EEEE-SSSSS CS
  HI0933_like   2 dviviGgGaAGlmaAisaakrgkrVlllekakkl 35 
                  ++i++G+G+ G   A   ++ g++V+l+ ++ ++
   EEA22333.1 722 HLIILGAGPVGSEMATFYSAIGSKVTLISSTAEI 755
                  589*********9999999********9887665 PP

  == domain 3  score: 9.8 bits;  conditional E-value: 0.00027
                  HHHHHHHHHT-EEE-S--EEEEECETTE.EEEEE.TTEEEEESEEEE--- CS
  HI0933_like 114 allkelkeagvklrletevksvekeedgkfrvktkseeeleadklvlAtG 163
                  +  k l+++gv+++l+++v ++ek++ ++++v ++s+e+++ + l+ AtG
   EEA22333.1 766 IVRKSLEASGVSIKLSSRVDKIEKHAANSLTVVLSSGETISGSVLLNATG 815
                  567899****************************9***********9*99 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.0   0.1    0.0097        10       1      31 [.     545     573 ..     545     580 .. 0.89
   2 ?    2.4   0.1      0.06        63       2      36 ..     723     755 ..     722     760 .. 0.89
   3 !    9.9   0.0   0.00033      0.35      97     147 ..     771     820 ..     762     833 .. 0.79

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0097
  Lycopene_cycl   1 DvvviGaGpAglslAarlteakpglkvvlie 31 
                    D+++iG+Gp       rl  ak+gl+v +ie
     EEA22333.1 545 DIIIIGGGPVTSFAESRL--AKAGLSVAVIE 573
                    9********998777888..*********97 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.06
  Lycopene_cycl   2 vvviGaGpAglslAarlteakpglkvvlieaspsl 36 
                    +++ GaGp g  +A     ++ g kv+li + +++
     EEA22333.1 723 LIILGAGPVGSEMATFY--SAIGSKVTLISSTAEI 755
                    79*************99..9*********776655 PP

  == domain 3  score: 9.9 bits;  conditional E-value: 0.00033
  Lycopene_cycl  97 lvengv.klleakvesveeeeageslvvleggrkirarlvvdarglaslkka 147
                    l  +gv + l+++v+++e++ a   +vvl+ g++i +++ + a+g  ++++ 
     EEA22333.1 771 LEASGVsIKLSSRVDKIEKHAANSLTVVLSSGETISGSVLLNATG--RRPRT 820
                    44444415689********999999********************..55555 PP

>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.2   8.3e-07   0.00087      24     116 ..      98     188 ..      78     213 .. 0.79

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 8.3e-07
  Fungal_trans_2  24 frkvllplalsnkallhallalsafhlqskgpkdslereakrykslalkelqealaelsstls..rnekykdiLaaiLllcsieissgdvsdwrv 116
                     + +++ + + +++a+ ha+ alsa++ ++ ++k    + +  + + al + ++a++ l++ ls  +++   +++a+ Ll   +e+++gd   w +
      EEA22333.1  98 WTRIIPQQCYHEPAIKHAIFALSALYKSAISSKTNTANLDDEHFNFALVQQRQAINSLRQALSsgQPQMRLALVAS-LLFSCFESFHGD---WET 188
                     5566667788899**************8888888888899999999999999999999999996333333444444.777778899999...765 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0     0.021        22       9      40 ..     545     576 ..     539     631 .. 0.78
   2 !   10.6   0.1   0.00055      0.58       3      43 ..     716     755 ..     714     806 .. 0.73

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.021
  NAD_binding_7   9 kvlvvGgGevAarkvrklleagakvtvvapev 40 
                     ++++GgG+v     ++l++ag  v v+  e+
     EEA22333.1 545 DIIIIGGGPVTSFAESRLAKAGLSVAVIEHEL 576
                    689*************************9986 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00055
  NAD_binding_7   3 ldlkgkkvlvvGgGevAarkvrklleagakvtvvapevkee 43 
                     ++  ++ ++ G+G+v+ + +    + g kvt+++ +  e+
     EEA22333.1 716 ANIAPEHLIILGAGPVGSEMATFYSAIGSKVTLISSTA-EI 755
                    6778899****************************994.33 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.1   0.2    0.0003      0.31       1      61 [.     545     607 ..     545     621 .. 0.84
   2 !    7.1   0.2    0.0024       2.5       2      38 ..     723     758 ..     722     795 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.0003
                 CEEEE-SSHHHHHHHHHHHHTT--EEEEES-G..GGTT--SSSSEEE-TTHHHHHHHHHHHT- CS
        GIDA   1 dviViGgGhAGceAAlaaarlGakvlLithkl..dtiaelsCnpsiggiakgllvrEidalgg 61 
                 d+i+iGgG   + A   +a++G++v+ i h+l  +++   +C ps   +   +  +  +a++g
  EEA22333.1 545 DIIIIGGGPVTSFAESRLAKAGLSVAVIEHELygGECHFFGCIPSKALLRPVEAFEAAKAIDG 607
                 79**************************66543389*********999877777766666666 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0024
                 EEEE-SSHHHHHHHHHHHHTT--EEEEES-GGGTT-- CS
        GIDA   2 viViGgGhAGceAAlaaarlGakvlLithkldtiael 38 
                 +i++G+G  G+e A   +  G kv+Li  ++ +i+ +
  EEA22333.1 723 LIILGAGPVGSEMATFYSAIGSKVTLI-SSTAEILPM 758
                 699************************.666666655 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.1   0.0   3.8e-05      0.04      16      56 ..     542     581 ..     532     600 .. 0.83
   2 ?   -0.2   0.1      0.46   4.9e+02      14      47 ..     717     749 ..     711     755 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 3.8e-05
                 TEEEEEEE--SHHHHHHHHHHHHCTTS-EEEEESSSS--TT CS
        Thi4  16 aesDvvivGaGssGLtaayylakkpdlkvailersvspGGG 56 
                    D++i+G+G+    a   lak+ +l va++e+++  G  
  EEA22333.1 542 TAFDIIIIGGGPVTSFAESRLAKA-GLSVAVIEHELYGGEC 581
                 567*********************.*********9965544 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.46
                 HHTEEEEEEE--SHHHHHHHHHHHHCTTS-EEEE CS
        Thi4  14 kyaesDvvivGaGssGLtaayylakkpdlkvail 47 
                 ++a   ++i GaG+ G   a   +   + kv+++
  EEA22333.1 717 NIAPEHLIILGAGPVGSEMATFYSAI-GSKVTLI 749
                 5667789*********9988877766.6777766 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   0.1    0.0014       1.5       3      32 ..     545     574 ..     543     576 .. 0.94
   2 !    6.3   0.1    0.0047         5       5      36 ..     724     755 ..     721     794 .. 0.87

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0014
                    EEEEE--SHHHHHHHHHHHHTTHHEEEEES CS
  FAD_binding_3   3 dVlIVGaGpaGlmlallLseaGvrvvlvek 32 
                    d++I+G+Gp+   + + L++aG +v ++e 
     EEA22333.1 545 DIIIIGGGPVTSFAESRLAKAGLSVAVIEH 574
                    899*************************95 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0047
                    EEE--SHHHHHHHHHHHHTTHHEEEEESSSSS CS
  FAD_binding_3   5 lIVGaGpaGlmlallLseaGvrvvlvekrstt 36 
                    +I GaGp+G   a++ s  G +v+l+   ++ 
     EEA22333.1 724 IILGAGPVGSEMATFYSAIGSKVTLISSTAEI 755
                    699***********************988765 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.1    0.0017       1.8       1      27 [.     548     574 ..     548     584 .. 0.90
   2 ?    3.9   0.1     0.062        65       1      26 [.     725     750 ..     725     755 .. 0.91

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0017
                    EE--SHHHHHHHHHHHCCTEEEEEE-S CS
  NAD_binding_8   1 IvGaGlsGlvaAylLakagfdvlllek 27 
                    I+G+G   + a ++Lakag++v ++e+
     EEA22333.1 548 IIGGGPVTSFAESRLAKAGLSVAVIEH 574
                    9************************97 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.062
                    EE--SHHHHHHHHHHHCCTEEEEEE- CS
  NAD_binding_8   1 IvGaGlsGlvaAylLakagfdvllle 26 
                    I+GaG  G+ +A +++  g +v+l+ 
     EEA22333.1 725 ILGAGPVGSEMATFYSAIGSKVTLIS 750
                    89*********************986 PP

>> XdhC_C  XdhC Rossmann domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0      0.74   7.8e+02       2      30 ..     547     575 ..     546     621 .. 0.91
   2 ?   11.2   0.0   0.00039      0.41       1      35 [.     723     774 ..     723     832 .. 0.67

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.74
                 EEE--STTHHHHHHHHHHHTEEEEEEES- CS
      XdhC_C   2 vifGaghvaqalarlaaalgfrvtvvdpr 30 
                 +i+G+g+v+    + +a++g++v v++++
  EEA22333.1 547 IIIGGGPVTSFAESRLAKAGLSVAVIEHE 575
                 89***********************9875 PP

  == domain 2  score: 11.2 bits;  conditional E-value: 0.00039
                 EEEE--STTHHHHHHHHHHHTEEEEEEES-GGGG.................- CS
      XdhC_C   1 lvifGaghvaqalarlaaalgfrvtvvdpreefa.................t 35 
                 l+i+Gag+v+ ++a++ +a+g +vt++ + +e+                  +
  EEA22333.1 723 LIILGAGPVGSEMATFYSAIGSKVTLISSTAEILpmvegaaakivrksleaS 774
                 79**************************999876555554444444444440 PP

>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   9.5e-05       0.1      24      69 ..     708     753 ..     694     778 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 9.5e-05
                   HTTCCGSBS-GTTSEEEEES-SHHHHHHHHHHHHTT-EEEEESSSH CS
  2-Hacid_dh_C  24 ksekallgkelsgktvGiiGlGrIGqavakrlkafgmkviaydrsk 69 
                   +s+++    +++ + + i+G+G +G+++a   +a+g kv+ ++ + 
    EEA22333.1 708 WSNRDAVAANIAPEHLIILGAGPVGSEMATFYSAIGSKVTLISSTA 753
                   5888888999******************************998875 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.1       2.1   2.3e+03       2      29 ..     546     573 ..     545     575 .. 0.89
   2 ?   11.3   0.1   0.00022      0.23       3      56 ..     724     777 ..     722     800 .. 0.82
   3 ?   -2.7   0.0       4.4   4.6e+03       8      31 ..     924     946 ..     923     950 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 2.1
                 EEEE--SCCHHHHHHHHHHTT-EEEEE- CS
     3HCDH_N   2 vaviGaGtmGagiaavfasagleVvlvd 29 
                 + +iG G + +   + +a+agl+V +++
  EEA22333.1 546 IIIIGGGPVTSFAESRLAKAGLSVAVIE 573
                 6699*****9999999********9987 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00022
                 EEE--SCCHHHHHHHHHHTT-EEEEE-S-HHHHHHHHHHHHHHHHCCTTTTSS- CS
     3HCDH_N   3 aviGaGtmGagiaavfasagleVvlvdiseealekalekieksleklvekgklk 56 
                  ++GaG +G+++a+   + g +V+l+  ++e+l  ++ +++k ++k  e+  ++
  EEA22333.1 724 IILGAGPVGSEMATFYSAIGSKVTLISSTAEILPMVEGAAAKIVRKSLEASGVS 777
                 589*****************************9999999999888877766655 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 4.4
                 SCCHHHHHHHHHHTT-EEEEE-S- CS
     3HCDH_N   8 GtmGagiaavfasagleVvlvdis 31 
                 Gt+G+  a++  sagl+V+ vd +
  EEA22333.1 924 GTVGHTFASA-QSAGLKVRAVDSD 946
                 8999998864.678*****99975 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.1       2.5   2.7e+03      30      58 ..     545     573 ..     541     576 .. 0.82
   2 ?   10.1   0.4   0.00034      0.36      26      91 ..     718     793 ..     711     807 .. 0.82

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 2.5
                  EEEEESTSHHHHHHHHHHHHTT-EEEEEE CS
  AlaDh_PNT_C  30 kvlviGgGvaGlqAiatakglgakVtvlD 58 
                   +++iGgG +   A +  ++ g +V v++
   EEA22333.1 545 DIIIIGGGPVTSFAESRLAKAGLSVAVIE 573
                  589*****999999988888888888876 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00034
                  B---EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTTCECEE..........HCHHHHHHHHHHHH CS
  AlaDh_PNT_C  26 vepakvlviGgGvaGlqAiatakglgakVtvlDvrparleqleslgakfvev..........lksqeellaeavke 91 
                  ++p + +++G+G +G + +   +++g kVt++   ++ l  +e   ak+v+           l+s  +++++++++
   EEA22333.1 718 IAPEHLIILGAGPVGSEMATFYSAIGSKVTLISSTAEILPMVEGAAAKIVRKsleasgvsikLSSRVDKIEKHAAN 793
                  568999*************************************999997776777777777766666666666655 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.1    0.0037       3.9       1      33 [.     545     578 ..     545     592 .. 0.92
   2 ?    1.4   0.3      0.18   1.9e+02       1      48 [.     722     771 ..     722     801 .. 0.77
   3 ?    1.2   0.0      0.21   2.2e+02     153     201 ..     768     815 ..     758     838 .. 0.77

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0037
                 EEEEECTSHHHHHHHHHHHHTT..EEEEESSSSTT CS
         DAO   1 dvviiGGGiiGlstAyeLarrg..Vtllekgdiag 33 
                 d++iiGGG + +++   La++g  V+++e +   g
  EEA22333.1 545 DIIIIGGGPVTSFAESRLAKAGlsVAVIEHE-LYG 578
                 8****************************88.555 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.18
                 EEEEECTSHHHHHHHHHHHHTT..EEEEESSSSTTSSGGGSSEEEEESSS CS
         DAO   1 dvviiGGGiiGlstAyeLarrg..VtllekgdiagsgaSgrnsgllhsgl 48 
                 +++i G+G +G+  A + ++ g  Vtl+ +  ++     g+++++++ +l
  EEA22333.1 722 HLIILGAGPVGSEMATFYSAIGskVTLISSTAEILPMVEGAAAKIVRKSL 771
                 6799*******9999999887889***99987666688888888887766 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.21
                 HHHHHHTT-EEEESECEEEEEEEE.TCEEEEEEECTEEEEEEEEEEE--G CS
         DAO 153 araaealGveilegtevtgleeed.gkvwgverttpgendaadavVnaaG 201
                 ++ +ea Gv i + ++v ++e++  + ++ v   ++ge+ +   + na+G
  EEA22333.1 768 RKSLEASGVSIKLSSRVDKIEKHAaNSLTVV--LSSGETISGSVLLNATG 815
                 45699***************98774554444..55576634467999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1027 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       596  (0.0332422); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              17  [number of targets reported over threshold]
# CPU time: 0.81u 0.30s 00:00:01.11 Elapsed: 00:00:00.47
# Mc/sec: 6637.34
//
Query:       EEA22334.1  [L=621]
Description: pogo transposable element, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.6e-23   81.5   0.0    1.1e-22   80.5   0.0    1.5  1  DDE_1         DDE superfamily endonuclease
    9.1e-09   35.2   0.3    3.1e-08   33.5   0.3    2.0  1  HTH_Tnp_Tc5   Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
      0.055   12.4   1.6      0.083   11.8   1.6    1.2  1  Amidase       Amidase


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.5   0.0   1.9e-26   1.1e-22       2     175 .]     193     368 ..     192     368 .. 0.89

  Alignments for each domain:
  == domain 1  score: 80.5 bits;  conditional E-value: 1.9e-26
       DDE_1   2 erltvllcanaagsekLkplvigkak..sprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrleaekrk..ilLlldssrshetvel.le 94 
                 +++ ++++++ a++  + p +i+ ak  +++ ++    ++++  + +  ++ +w+ ++++ +WL +vfdk ++++ ++   lL+ld+++sh t+ + + 
  EEA22334.1 193 REWITTIGCICANGTAISPALIYMAKsgNLQDSWLQDFDAEQHRCFFATSESGWTNNEVGFAWLvNVFDKETKSQASRgwRLLILDGHGSHVTMRFiEY 291
                 678999****************9665226888999999***********************************666652267**************999 PP

       DDE_1  95 selqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                 ++++   l+++Pa+s+++lqPld+ ++s+l + Y +ql + +++  +        lt +d+++   ++w+  +++e+i saf
  EEA22334.1 292 CDKNRFLLAIFPAHSTHTLQPLDVAIFSPLSTAYTEQL-RRFINDCQGFTR----LTKRDFFRLFWASWEaTFTSENILSAF 368
                 **********************************8765.556666655555....9**************99******9987 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.5   0.3   5.2e-12   3.1e-08       2      60 ..      59     108 ..      58     115 .. 0.91

  Alignments for each domain:
  == domain 1  score: 33.5 bits;  conditional E-value: 5.2e-12
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh 60 
                  +e+ + L++Wi+ql+erg p+t++++ + A+e+         + + ++k+W  r++k h
   EEA22334.1  59 KEQSRTLIKWINQLTERGLPPTNSMLENFAREI---------SGKEPGKNWASRWLKAH 108
                  68999****************************.........67889**********99 PP

>> Amidase  Amidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   1.6   1.4e-05     0.083     309     396 ..     498     589 ..     470     612 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 1.4e-05
                 ---SS-SCCCCCCCHHHHCCS-HHHHHHHHHHHHHCSCCCCCCCHHHHHHHHH.HHHHHHHHHCCC...BSEEEEESSSSS--BCCCCCHHH CS
     Amidase 309 erlsetkvlsellpksraellgeevkrrielgnyalsaeasskyylkaqkvrr.llrrefakafee...lDvllsPtaptpaprlgekdkti 396
                 +  + ++  +++  k+ +++l+++ k + +    ++ +e++++ +++a++ +r   ++e+ak+ +     Dvl++P+ap+ a+++  k+ ++
  EEA22334.1 498 KDEQAAQEQARKDDKKLQQELTKQAKEQEKAERAQIRQEKQEQRLQEATEKQRlKDEQELAKLAHLqlqNDVLATPSAPKRAKKQVSKQVKV 589
                 2333344445666667777777777777777777777777777777777666656667777765557778*************998887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (621 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3073  (0.171398); expected 358.6 (0.02)
Passed bias filter:                      868  (0.0484132); expected 358.6 (0.02)
Passed Vit filter:                       169  (0.00942607); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.83u 0.32s 00:00:01.14 Elapsed: 00:00:00.43
# Mc/sec: 4310.18
//
Query:       EEA22335.1  [L=369]
Description: CRAL/TRIO domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.5e-25   87.2   0.0    2.1e-24   86.0   0.0    1.6  2  CRAL_TRIO      CRAL/TRIO domain
    0.00015   21.9   0.0    0.00045   20.3   0.0    1.9  1  CRAL_TRIO_N    CRAL/TRIO, N-terminal domain
  ------ inclusion threshold ------
      0.092   12.9   0.1       0.47   10.6   0.0    2.1  2  Ribosomal_L10  Ribosomal protein L10
        0.1   12.8   0.0       0.21   11.7   0.0    1.6  1  CRAL_TRIO_2    Divergent CRAL/TRIO domain


Domain annotation for each model (and alignments):
>> CRAL_TRIO  CRAL/TRIO domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.0   0.0   4.8e-28   2.1e-24      12     159 .]     101     286 ..      91     286 .. 0.83
   2 ?   -2.8   0.0         1   4.6e+03      81     104 ..     293     317 ..     288     318 .. 0.79

  Alignments for each domain:
  == domain 1  score: 86.0 bits;  conditional E-value: 4.8e-28
   CRAL_TRIO  12 hgr.Dkegrpvlylrlgrfdpkklsle..............................elvralvlvlerllkelee........dgqvegvtvviDlkg 71 
                 +gr  k+g p++++ + + d + +++                               + + ++ +v+++l+ ++ +        +g+ + +++++++ +
  EEA22335.1 101 TGRfNKRGLPIFVFDVVNLDNEAIKSYertrnlksvpineislatekpvatslsrpqRALIYHDYVTRFLFPLCSKlsqsevkeKGETTHCIYLVNIAN 199
                 455589999*****99999999555333567888889999999999999999999995555555555554443333333444569************** PP

   CRAL_TRIO  72 lslskmlwkpisllkkilkilqdnyperlgkilivnaPklfkfafklvkpfldektreKikfvspsnteatlekyidpeqlpkelGGt 159
                 ++l+++  +   ++++++ +l +nype + +i+++naP+++++++ l+k f+d++t++K+++vsp+++ ++l++ id e++pk +GG+
  EEA22335.1 200 MTLKQVW-DLRNYAQDVSRLLATNYPEVVDRIYVLNAPSYYNTIWGLIKRFIDPVTADKLVIVSPNEVLEELSEDIDLENIPKVFGGE 286
                 **66655.66*****************************************************************************6 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1
   CRAL_TRIO  81 p.isllkkilkilqdnyperlgkil 104
                 + +s++k+++++++ n p+  g+il
  EEA22335.1 293 MlPSIAKELWQTINWNDPDSTGQIL 317
                 4488999999999999999888886 PP

>> CRAL_TRIO_N  CRAL/TRIO, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0     1e-07   0.00045       3      53 ..      15      67 ..      13      68 .. 0.72

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 1e-07
  CRAL_TRIO_N  3 dellahlqeseyk.....lteeekfW.ltredhddaclLRfLRArkwdvekAikrLe 53
                 +el + +++ ++      l++   +  l +e    a+lLRfL Ar +dv+ A k+ +
   EEA22335.1 15 QELTDLCSKDGLLirpqgLQDNDMLNgLMDE----ATLLRFLNARGFDVQGALKQYK 67
                 5555555555555666666666666666666....8******************976 PP

>> Ribosomal_L10  Ribosomal protein L10
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0      0.82   3.7e+03       4      38 ..      72      92 ..      45      96 .. 0.62
   2 ?   10.6   0.0    0.0001      0.47      11      45 ..     180     214 ..     177     220 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.82
                   CCHCCCCCCCCCCCTTSSEEEEEE-TTS-HHHHHH CS
  Ribosomal_L10  4 ekKeelvkelkellkkyksvvvvdyegltvaqlqe 38
                   + K++ ++el+              ++++v+ ++e
     EEA22335.1 72 AHKNNHIAELY--------------DEIDVKVFEE 92
                   33333333333..............4555555555 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.0001
                    CCCCCCCTTSSEEEEEE-TTS-HHHHHHCCCHHHH CS
  Ribosomal_L10  11 kelkellkkyksvvvvdyegltvaqlqelRkklre 45 
                    +e+ke+ +++ ++++v+++++t +q+ +lR+  ++
     EEA22335.1 180 SEVKEKGETTHCIYLVNIANMTLKQVWDLRNYAQD 214
                    58999*************************97765 PP

>> CRAL_TRIO_2  Divergent CRAL/TRIO domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   4.8e-05      0.21      57     136 ..     210     290 ..     158     292 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 4.8e-05
  CRAL_TRIO_2  57 swlkkvystlprrykknlkklyivhpstfvktllktvlsafvsskfrkkvey..vsrleeLarkidrtqllkslPegvvshd 136
                  ++++ v ++l  +y++ + ++y++++ ++  t+   + +++     +k v++   + leeL++ id+++++k ++ g ++++
   EEA22335.1 210 NYAQDVSRLLATNYPEVVDRIYVLNAPSYYNTIWGLIKRFIDPVTADKLVIVspNEVLEELSEDIDLENIPKVFG-GEFDYQ 290
                  677888999*************************6666666555554444443346799*************999.666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (369 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       509  (0.0283898); expected 358.6 (0.02)
Passed bias filter:                      457  (0.0254894); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 2503.10
//
Query:       EEA22336.1  [L=357]
Description: glycosyl hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.7e-54  184.2   0.0    4.5e-54  184.0   0.0    1.0  1  Glyco_hydro_3  Glycosyl hydrolase family 3 N terminal domain


Domain annotation for each model (and alignments):
>> Glyco_hydro_3  Glycosyl hydrolase family 3 N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  184.0   0.0   2.5e-58   4.5e-54      17     319 .]      40     351 ..      25     351 .. 0.90

  Alignments for each domain:
  == domain 1  score: 184.0 bits;  conditional E-value: 2.5e-58
                    -S--HHHHHHHHHH--SEEE--GGGTSSHHHHHHHHHHHHHH-SS....S--EEEE---BTTB---SSS---S-HHHHHHHT-HH.HHHHHHHHHH CS
  Glyco_hydro_3  17 ekkseeaaellkkyqvGgiilfaenledtkqleelieaarqaseksrlgiPlllavDqegGlvqrlgegtlfPsalalaatssld.likelgriia 111
                      + +e   l+k+  vGg+ilf++n++++      + +   as+   +g Pll+ +DqegG v rl   + + s+ +++++s+++  + ++g+ +a
     EEA22336.1  40 STPPAELTTLIKQGLVGGVILFGGNVNSNLPGTINSWQKAYASSPAYIGSPLLIMTDQEGGKVRRLPG-GPISSEKVIGESSNPEqSASQAGSDAA 134
                    566788999****************9987765555555555666667899*************99996.888999********9978********* PP

                    HHHHHHT--EE---B-----STTSS..SGGGSS-SSHHHHHHHHHHHHHHHHHTT-EEEEEEETTGTT-S.SETTTSEEB-.---HHHHHHTTHHH CS
  Glyco_hydro_3 112 kelralgididfaPvvdvnrdprng..igvrsFsedpelvaalaaamvkGlqgagvaatvKHFpghGdga.vdshkelptv.dhseeelrevdlvp 203
                    + l a ++++++aPv+dv r p +     +rs+s++  l++  +aa+ ++ qgag +at+KHFpg G  + +++  e+p++ + +  e+r+vd  p
     EEA22336.1 135 AALGAYNMNTNLAPVLDVFRTPGDFedQYQRSYSDNATLAGICGAAFTTAQQGAGYIATAKHFPGLGSASsTENTDEVPVTlNLTIGEIRAVDEIP 230
                    **********************88656899************************************976515555566654367899********* PP

                    HHHHHHTT-SEEEE---B-TTT---.BGGG-HHHHIIIIIIIS---SEEEES-TTSHHHHCCS-HHHHHHHHHHHT-SBEES-S---SG....HHH CS
  Glyco_hydro_3 204 fqaaieagvdsVMtaHvqfpaldgt.patgskklltdvLRkelGFdGvvvsDalamkeiadrggkeeavvlaLkAGvDilLvpeertse....ika 294
                    + +ai+ag+d++M++   +p++d++ p  +s+k+l++ LR +lGF+Gv++sDa+  ++++  g++++++vla  AG+Di+L  ++ +++    ++a
     EEA22336.1 231 YYNAIAAGIDMIMPSWALYPDFDSQyPSGLSEKWLKQELRGRLGFQGVTISDAIEAGALTAFGSDSQRAVLASGAGMDIILAAAQNVTQgktiVNA 326
                    *************************9*********************************************************99988899999** PP

                    HHHHHHTTSS-HHHHHHHHHHHHHH CS
  Glyco_hydro_3 295 lkkavkeGeltearidesvrrvlrl 319
                    l++a+++G l   ++ ++ +r+++l
     EEA22336.1 327 LANALNSGALDTVEFSAATQRIIQL 351
                    **********************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (357 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       338  (0.0188521); expected 358.6 (0.02)
Passed bias filter:                      260  (0.0145016); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.23s 00:00:00.68 Elapsed: 00:00:00.40
# Mc/sec: 2669.87
//
Query:       EEA22337.1  [L=176]
Description: hypothetical protein PMAA_061160 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.023   14.7  11.2      0.032   14.2  11.2    1.2  1  Mucin     Mucin-like glycoprotein
      0.041   13.7   5.5      0.077   12.9   5.5    1.4  1  Beta-APP  Beta-amyloid peptide (beta-APP)


Domain annotation for each model (and alignments):
>> Mucin  Mucin-like glycoprotein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2  11.2   3.6e-06     0.032      45     134 ..      33     123 ..      19     127 .. 0.75

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 3.6e-06
       Mucin  45 ltttttttkppttttttttasttitt.kttkattttttttttttateaPsdavttaeaPtttttrapsrlrevdGslsssaWvcaPLllav 134
                 +t t+tt+   +t t+ +t s t t    t a+t+t  ++ tt++   P +++ + +aP+ +tt + s+   + G + + + v   Ll+a+
  EEA22337.1  33 MTPTATTIAVGSTLTAISTDSLTHTGlSITLAATATKIQSGTTSTNLLPDSSTGSIDAPSINTTASVSNNGAIVGDIVGGVVVIGSLLVAI 123
                 333444444445555555777776651446677777778888888889*****************9***999***9999999999998875 PP

>> Beta-APP  Beta-amyloid peptide (beta-APP)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   5.5   8.6e-06     0.077      23      38 ..     100     115 ..      98     116 .. 0.94

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 8.6e-06
    Beta-APP  23 SNKGAIIGLMVGGVVI 38 
                 SN GAI+G +VGGVV+
  EEA22337.1 100 SNNGAIVGDIVGGVVV 115
                 9*************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (176 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       494  (0.0275531); expected 358.6 (0.02)
Passed bias filter:                      278  (0.0155056); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.27s 00:00:00.69 Elapsed: 00:00:00.44
# Mc/sec: 1212.54
//
Query:       EEA22338.1  [L=348]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.8e-87  291.0   0.1    7.2e-87  290.7   0.1    1.1  1  DUF3431   Protein of unknown function (DUF3431)
  ------ inclusion threshold ------
          1    9.3   3.2        0.4   10.6   0.4    1.8  2  MRAP      Melanocortin-2 receptor accessory protein family


Domain annotation for each model (and alignments):
>> DUF3431  Protein of unknown function (DUF3431)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  290.7   0.1     8e-91   7.2e-87       1     215 []      82     301 ..      82     301 .. 0.96

  Alignments for each domain:
  == domain 1  score: 290.7 bits;  conditional E-value: 8e-91
     DUF3431   1 lVvaklkeedtsWveeelpdlqtaiYvvddpsaeltvpankGreamaYltyiidnYdsLpdvvvFvhahraawhndaldydnaallrrlrleavqeeGY 99 
                 lVva+lk+++tsW ++++pd++++iYvvddp a+ltvp nkG+eam+Yltyiid+Yd+Lp+ ++F+ha+r++whnd++dyd   llr+++++++qeeGY
  EEA22338.1  82 LVVASLKQQHTSWYSTYFPDWKSNIYVVDDPGASLTVPLNKGNEAMVYLTYIIDRYDTLPNNTLFLHAERFQWHNDNPDYDGYPLLRDFQFTYLQEEGY 180
                 8************************************************************************************************** PP

     DUF3431 100 vnlrckwepgCpaelkplekee.....eekkeeealaeafaelfeeeevpevvaapcCaqFavsrerirkrpreeYvrlrqwlletelddelsGrvley 193
                 vnlrc w+ gCp +++p+e+e      +++++ e++++af+el++e +vp +v+ +cCaqFav++e ir+rp+e+Y+++r+wll+t  d+ lsGrv+ey
  EEA22338.1 181 VNLRCVWTIGCPVSIHPFEDEViseqhQDQTTGEIYKHAFEELLPEYPVPGEVGISCCAQFAVTKEVIRQRPKEDYIHFRDWLLNTPFDNGLSGRVFEY 279
                 ******************95556764444444559999999999******************************************************* PP

     DUF3431 194 lWhilFgkeavaCpdeeecycd 215
                 +Whi+Fgk++v+Cp+++ecyc+
  EEA22338.1 280 SWHIIFGKSPVYCPSAAECYCK 301
                 *********************6 PP

>> MRAP  Melanocortin-2 receptor accessory protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.4   4.5e-05       0.4      26      67 ..       4      40 ..       1      47 [. 0.82
   2 ?   -3.7   0.1       1.4   1.2e+04      13      23 ..      75      82 ..      65      98 .. 0.60

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 4.5e-05
        MRAP 26 vdekkLkankysiviafWvsLavfvvllflvLlylsksGspq 67
                +d + Lk  k  i     v+La+  + lf+vL yl ++G ++
  EEA22338.1  4 IDHRPLKTTKLVI-----VTLASTFISLFFVLFYLHHAGNSD 40
                5666777777655.....68*****************99875 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 1.4
        MRAP 13 syeYyldYldl 23
                +yeY +   +l
  EEA22338.1 75 DYEYDV---EL 82
                677722...33 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (348 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       433  (0.0241508); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.24s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2535.53
//
Query:       EEA22339.1  [L=584]
Description: ATP-dependent RNA helicase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.1e-46  157.9   0.0    1.9e-45  154.8   0.0    2.1  2  DEAD             DEAD/DEAH box helicase
    2.1e-25   89.2   0.0    9.9e-25   87.0   0.0    2.2  2  Helicase_C       Helicase conserved C-terminal domain
    1.9e-19   69.6   0.1    3.5e-19   68.8   0.1    1.5  1  DUF4217          Domain of unknown function (DUF4217)
    0.00074   18.8   0.0    0.00074   18.8   0.0    2.0  2  ERCC3_RAD25_C    ERCC3/RAD25/XPB C-terminal helicase
  ------ inclusion threshold ------
      0.036   13.8   0.0       0.14   11.9   0.0    2.0  1  RNA_pol_A_CTD    Bacterial RNA polymerase, alpha chain C term
        6.9    6.6  15.6         13    5.7  15.6    1.3  1  Spore_coat_CotO  Spore coat protein CotO


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  154.8   0.0   6.4e-49   1.9e-45       1     176 []     129     301 ..     129     301 .. 0.94
   2 ?    0.7   0.0      0.13     4e+02      65      94 ..     366     395 ..     362     425 .. 0.74

  Alignments for each domain:
  == domain 1  score: 154.8 bits;  conditional E-value: 6.4e-49
                 -HHHHHHHHHHHTTCEEEEEESTTSSHHHHHHHHHHHHHHHS..TTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   1 tdiQaeaiplilgggdvlvaaeTGsGKTlaflipvlqivyet..kgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldng 97 
                 t+iQ++aip ++ g+dvl+aa+TGsGKTlaflip+++ + +   k ++g+ +li++PtreLa q+   +++++++ + +   ++gg ++r + +kl++g
  EEA22339.1 129 TEIQQRAIPPLMAGRDVLGAAKTGSGKTLAFLIPAIELLHSLkfKPRNGTGVLILSPTRELALQIWGVARQLLDKHSQTHGIVMGGANRRAEAEKLEKG 227
                 79**********************************999777999999**************************977455589**************** PP

                 CSEEEEEHHHHHHHH.HCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHHHHH CS
                 xxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  98 vdivvgtpgrlddll.stgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlpkdvkkl 176
                 v+++v+tpgrl+d+l +t+ + ++++r lV+DEadr+l+ gf+d++++i++ l      g+ +rq+ ++SAT +++v++l
  EEA22339.1 228 VNLLVATPGRLLDHLqNTKGFVFKNLRQLVIDEADRILEIGFEDEMKQIMKIL------GNGERQTSLFSATQTTKVEDL 301
                 *************9977888****************************99999......566789*********999875 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.13
                 HHHHHHTTTSTSEEEEEETTSSHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  65 nnlkkfkkyidlrvlliiggvaardqlskl 94 
                 n ++++++yidl vl+i g++++++  s++
  EEA22339.1 366 NYYSELLNYIDLPVLSIHGKQKQQKRTSTF 395
                 66788999*******999988887777665 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       1.5   4.6e+03      15      73 ..     176     234 ..     164     235 .. 0.52
   2 !   87.0   0.0   3.3e-28   9.9e-25       6     110 ..     343     446 ..     338     447 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.5
                 TTSEEEEEESSHH.HHHH...HHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEES CS
  Helicase_C  15 eggkilifvntid.rlek...vklllekkgikvavlhgelpqnereeileqfnkgesdvLiat 73 
                 +g  +li ++t++  l+    ++ ll k++ +  ++   +   +r++  e+  k  +++L+at
  EEA22339.1 176 NGTGVLILSPTRElALQIwgvARQLLDKHSQTHGIV---MGGANRRAEAEKLEK-GVNLLVAT 234
                 556678888888854433555444444443333233...334555555556633.34666665 PP

  == domain 2  score: 87.0 bits;  conditional E-value: 3.3e-28
                 HHHHHHHTTTTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSSHHHHHHHH CS
  Helicase_C   6 llellkleeeggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprnvtsyiqri 104
                 l  +l +++ ++ki++f+ ++++++  + ll+  ++ v+ +hg+ +q++r  ++ +f + e+ +Li+tdva+rG+dip++++V+++d+p+++++yi+r+
  EEA22339.1 343 LFSFL-KRNLKKKIIVFLSSCNSVNYYSELLNYIDLPVLSIHGKQKQQKRTSTFFEFVNSERGILICTDVAARGLDIPEIDYVVQYDPPDDPRDYIHRV 440
                 55566.78899***********9987555556669**********************999999************************************ PP

                 TTSSST CS
  Helicase_C 105 GRtgRa 110
                 GRt+R+
  EEA22339.1 441 GRTARG 446
                 *****6 PP

>> DUF4217  Domain of unknown function (DUF4217)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.8   0.1   1.2e-22   3.5e-19       1      61 []     488     548 ..     488     548 .. 0.98

  Alignments for each domain:
  == domain 1  score: 68.8 bits;  conditional E-value: 1.2e-22
     DUF4217   1 iqqkleslcakdrdlkelAqkAfvsyvraYsvhlakeiFrvkkLdlealAksfGLleaPki 61 
                 +q++le+l++++++l+++A+++++sy+ aY++h+++++F+v+kLdl ++AksfG++ +P++
  EEA22339.1 488 VQSQLEKLISQNYYLNKSAKEGYRSYINAYASHSLRSVFDVNKLDLVKIAKSFGFSTPPRV 548
                 699********************************************************97 PP

>> ERCC3_RAD25_C  ERCC3/RAD25/XPB C-terminal helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.7   3.8       3.7   1.1e+04     194     238 ..      35      79 ..      15      88 .. 0.63
   2 !   18.8   0.0   2.5e-07   0.00074      56     152 ..     348     447 ..     321     458 .. 0.74

  Alignments for each domain:
  == domain 1  score: -4.7 bits;  conditional E-value: 3.7
  ERCC3_RAD25_C 194 viteleeleeeeelaystkeeqkellqkvlaakdeeaeeeeleke 238
                    vi + e+ +++++ + ++ ee++++ + + + ++e+++ e++++e
     EEA22339.1  35 VIDTSEKPKKQKTANPKKDEEENDVEEPIDQVEEEQEDGEKEQEE 79 
                    555555556655555566666666666665555555554444443 PP

  == domain 2  score: 18.8 bits;  conditional E-value: 2.5e-07
  ERCC3_RAD25_C  56 hekrgDkiivfsDnvfaLkeyakklkk.....pyiyGetseaerlkilqkfkknpkvntiflskvgDtsiDlPeanvliqisshfgsrrqeaqrlG 146
                    + + + kiivf  +  +++ y++ l++       i+G+ ++++r++ + +f ++++   ++   v+   +D+Pe   ++q +      r    r+G
     EEA22339.1 348 KRNLKKKIIVFLSSCNSVNYYSELLNYidlpvLSIHGKQKQQKRTSTFFEFVNSERG-ILICTDVAARGLDIPEIDYVVQYDPPDD-PRDYIHRVG 441
                    334478************99999988622222479****************988765.556689****************987665.457788888 PP

  ERCC3_RAD25_C 147 riLrak 152
                    r  r  
     EEA22339.1 442 RTARGA 447
                    888754 PP

>> RNA_pol_A_CTD  Bacterial RNA polymerase, alpha chain C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   4.7e-05      0.14      10      43 ..     102     135 ..      97     144 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 4.7e-05
                    XX--BHHHHT--HHHHHHHHHTT--BHHHHHHS- CS
  RNA_pol_A_CTD  10 klsisIeeLeLSvRslNcLkragiktvgeLvkls 43 
                    +l ++  eL+LS R+l + k+ g +t  e+ ++ 
     EEA22339.1 102 SLPTKFTELNLSERTLEAIKEMGFETMTEIQQRA 135
                    56677789******************99998775 PP

>> Spore_coat_CotO  Spore coat protein CotO
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7  15.6    0.0042        13      31     108 ..       9      89 ..       2     117 .. 0.49

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0042
  Spore_coat_CotO  31 sfkeekkqaaakekkdeaeekkpekaveeeveqekkkeaaePaeqeeeekaeeeekkeeeeqkeeeeekqetvea...ekP 108
                        k+ kk + +++ +de+ ++ ++ +v +  e++kk+++a+P+++eee+  ee   + eeeq+  e+e++e  +    + P
       EEA22339.1   9 AEKQSKKIKRKHDVSDETVKSLKKAEVIDTSEKPKKQKTANPKKDEEENDVEEPIDQVEEEQEDGEKEQEEGQDNqleDLP 89 
                      223333333333334444444444444444788999******999988877764444333333333333332222123334 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (584 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1726  (0.0962686); expected 358.6 (0.02)
Passed bias filter:                      786  (0.0438396); expected 358.6 (0.02)
Passed Vit filter:                       112  (0.00624686); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.79u 0.32s 00:00:01.11 Elapsed: 00:00:00.46
# Mc/sec: 3834.52
//
Query:       EEA22340.1  [L=63]
Description: hypothetical protein PMAA_061190 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (63 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       345  (0.0192426); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.37u 0.25s 00:00:00.62 Elapsed: 00:00:00.41
# Mc/sec: 462.71
//
Query:       EEA22341.1  [L=268]
Description: hypothetical protein PMAA_061200 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.8e-06   25.4   0.0    8.3e-06   24.6   0.0    1.3  1  Peptidase_S64  Peptidase family S64


Domain annotation for each model (and alignments):
>> Peptidase_S64  Peptidase family S64
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.6   0.0   4.6e-10   8.3e-06     567     693 ..     116     256 ..     113     259 .. 0.76

  Alignments for each domain:
  == domain 1  score: 24.6 bits;  conditional E-value: 4.6e-10
  Peptidase_S64 567 vkfveydPaLrfdNlyvkkkvlklkr................glkvFKiGsttkyTkGelngik...lvYWldgk.lqssEF.vvnsdssplFAsg 641
                     + ve+dP+L+ +    ++kv +l +                   v+K Gs++  T G +n i+   + Y +dgk   + E+ ++ +    +FA+ 
     EEA22341.1 116 WALVEVDPTLVPKI--RRNKVKDLSKshcesrqilhaakprkMAVVYKQGSASGTTIGIVNPIQshvVSYNADGKrYVTREWgIIPAVDPKFFAKV 209
                    56789999998653..35678899889999999***9999977789***************98655356*****8345778746777556689*** PP

  Peptidase_S64 642 GDSGswiLtkledekgLgvlGmLHS..yDGelkqFGLFtpiseileRLeeVTgi 693
                    GDSGs++L++ +      ++Gm+     DG       Ft+i+ i   +e+VTg+
     EEA22341.1 210 GDSGSLVLERDT----ANCMGMIFGghVDGGPV---YFTSITAIATHIEKVTGL 256
                    ********8743....34666663211344432...689999999999999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (268 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       618  (0.0344693); expected 358.6 (0.02)
Passed bias filter:                      512  (0.0285571); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.24s 00:00:00.68 Elapsed: 00:00:00.38
# Mc/sec: 2100.26
//
Query:       EEA22342.1  [L=315]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.5e-39  136.0   0.0    2.9e-39  135.8   0.0    1.0  1  4HBT_3       Thioesterase-like superfamily
  ------ inclusion threshold ------
      0.022   14.1   0.1       0.15   11.4   0.0    2.2  3  Acyl-ACP_TE  Acyl-ACP thioesterase
        0.1   12.9   0.0       0.46   10.9   0.0    2.1  2  4HBT         Thioesterase superfamily


Domain annotation for each model (and alignments):
>> 4HBT_3  Thioesterase-like superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  135.8   0.0   4.9e-43   2.9e-39       2     248 .]      34     295 ..      33     295 .. 0.77

  Alignments for each domain:
  == domain 1  score: 135.8 bits;  conditional E-value: 4.9e-43
                 -GGGECTTC.-HHHHHHHHHHHHHHT..........-S.SSEEEEEEE-S---SEEEEEEEEEEE--SS-EEEEEEEEET.TEEEEEEEEEEE---T.. CS
      4HBT_3   2 rppwtpggagyGGyvlAlalraaqrtv.........pdprlhslhvyFlrpgdagpviyhvervrdGrsfstrtvelsqg.grpiftatasfgraes.. 88 
                 + +w++g  ++GG++l+l+ + +++ +         pdp + +  ++F++p++ g+v+++v+++   +++st++v+l+   g  +++at+  g++++  
  EEA22342.1  34 QWDWCGGLHAHGGLTLSLIFSTVRAFFlrkypstpqPDP-I-NSDIHFIQPAPQGRVVLTVTELSHAKRYSTVEVKLRDPaGTICTSATVIQGNLATed 130
                 679****999**************998899999988888.7.*************************************77*************99754 PP

                 .......---EE-------..GGGE-.--.--SSGGGSGG..TEEEE-HHT---S...........S-EEEEEEEETTTS-SSHHHHHHHHTT-.-GGG CS
      4HBT_3  89 .tgwe..lepaaapppvppp.deaal.aadeaplplfrrvpgflepfeprpaegg....kpdspagpkrvrqWvrlreggepahlaaLaylsDsfpvpr 178
                     +  ++p  +p ++p+   ++ +  +++   +l+  v  +++ +  ++a+ +    k++++ ++k++  Wvr+ + ++++++ +L++++D +  p+
  EEA22342.1 131 gP--SiaVPPVMTPAEIPDReRDCDQwIRSPLLVKLM-PVISKMRVLKRKEAKTQfwsrKGEAGLNTKET--WVRWEDLDQKLDVISLGVVCDNLL-PA 223
                 33..332555555566666634443323333333333.23344444444444333332112223336666..*****999**************54.56 PP

                 GTSS-.........SB--EEEEEEEE-S--S-...EEEEEE-SEEETTEEEEEEEEE-TTS-EEEEEEEEEET CS
      4HBT_3 179 vhglrldaea...sgwmpsldltiyfhrepaedeWllleaetpwagdgrglvearlwdedGrlvAtstQeglv 248
                  +++ ++ +a   ++++p+++++++++++p++ eWl+le+ ++++++gr+++++r++de+G+lvA+ ++++++
  EEA22342.1 224 PLNYDPT-MAnlsKYVFPTMCMSVEIKKDPKDAEWLFLEIVCHSIQNGRYDTDVRVLDENGDLVALGRHVSVM 295
                 6666654.2234569**************9767************************************9986 PP

>> Acyl-ACP_TE  Acyl-ACP thioesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0      0.37   2.2e+03      80     106 ..      93     119 ..      75     122 .. 0.69
   2 ?   -0.7   0.0      0.12   6.9e+02     149     167 ..     187     205 ..     157     210 .. 0.66
   3 ?   11.4   0.0   2.4e-05      0.15      61     124 ..     244     307 ..     234     315 .] 0.92

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.37
  Acyl-ACP_TE  80 waesenklfcyrdfkvrdekgekiiea 106
                     s+ k++   ++k+rd +g  +  a
   EEA22342.1  93 TELSHAKRYSTVEVKLRDPAGTICTSA 119
                  445788899999999999888665554 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.12
  Acyl-ACP_TE 149 eakeeseekelkvrysDlD 167
                  +  +  + ke  vr+ DlD
   EEA22342.1 187 KGEAGLNTKETWVRWEDLD 205
                  333445778999*****99 PP

  == domain 3  score: 11.4 bits;  conditional E-value: 2.4e-05
  Acyl-ACP_TE  61 yeieierlpefgdkveietwaesenklfcyrdfkvrdekgekiieaksvfvlmdqetrrlsrvt 124
                  +++ei++ p+ ++ +  e  ++s+++     d++v de+g+ ++    v v+ + ++ ++s++t
   EEA22342.1 244 MSVEIKKDPKDAEWLFLEIVCHSIQNGRYDTDVRVLDENGDLVALGRHVSVMAEMKRTKASKIT 307
                  89****************************************************9999999986 PP

>> 4HBT  Thioesterase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   0.0   7.7e-05      0.46      14      77 ..      54     115 ..      41     117 .. 0.67
   2 ?   -2.9   0.0       1.6   9.5e+03      63      74 ..     241     252 ..     241     254 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 7.7e-05
                 HHHHHHHHHHTTSTTEEEEEEEEEEEESS-BBTTCEEEEEEEEEEEESSEEEEEEEEEETTSCE CS
        4HBT  14 Deaagaalrslggrgilvvvvelsidflrpvrlgdeltvearvlrlgrtsavvevevrdedgrl 77 
                  ++++ +lr++  +   +  ++  i+f+ p+ +g +++++++ l   ++  +vev++rd  g+ 
  EEA22342.1  54 STVRAFFLRKYPST-PQPDPINSDIHFIQPAPQG-RVVLTVTELSHAKRYSTVEVKLRDPAGTI 115
                 55555555555555.555557889**********.77777777677777778899999877765 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.6
                 EEEEEEEEEETT CS
        4HBT  63 savvevevrded 74 
                 +++++ve+++++
  EEA22342.1 241 TMCMSVEIKKDP 252
                 6999****9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (315 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       390  (0.0217525); expected 358.6 (0.02)
Passed bias filter:                      361  (0.020135); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.23s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 2184.61
//
Query:       EEA22343.1  [L=313]
Description: glycosyl transferase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.9e-13   49.2   0.0    1.1e-12   48.0   0.0    1.5  1  Glyco_transf_8  Glycosyl transferase family 8


Domain annotation for each model (and alignments):
>> Glyco_transf_8  Glycosyl transferase family 8
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.0   0.0   6.4e-17   1.1e-12       4     254 ..      16     275 ..      14     277 .. 0.84

  Alignments for each domain:
  == domain 1  score: 48.0 bits;  conditional E-value: 6.4e-17
  Glyco_transf_8   4 laldknYllgasvviksllknakepawfalnfhiltaeievenleklnklassykevlellesdkksledfesklklrspkylsllnylRlylpe 98 
                     l  +  Yl g++++ +sl k  +    ++  + + t+++++e  + l++ +  +k+v  ll+s  k+     + ++ r   ++s+l+      ++
      EEA22343.1  16 LITNTAYLSGLLTLEYSLRKVGS----KYPLVALYTDTFPEEGHAALDARGILKKRVPYLLPSIPKD-----YTNDMRFYDCWSKLTP-----FS 96 
                     567889*****************....57777778*****************999998888776655.....2588999999998873.....34 PP

  Glyco_transf_8  99 lfpkldkilylDaDvvvqgdlseLwdldlk.gkvlaaved........................krfkkylnksepliaenfkpeacyF.....n 163
                     l +++d+++ lD+D +v ++++eL++l+l+ + +++  +                         + + ++ + ++p +a+   ++   F     n
      EEA22343.1  97 L-VEYDRVVQLDSDMLVLRNMDELMELELDaPDLAGTGNKvfaashacvcnplkkphypkdwisENCGYTSQHNTPDVAQTEGAS-PSFglgipN 189
                     4.677************************977777777779999999****************9888888887777777766544.444334448 PP

  Glyco_transf_8 164 aGvllfdldewrkenitetlikwlnlnekrtllklgdqdilnivfkgkvkeldkkynvlglgyeqskkskkeitenaaviHyiGpaKPWld 254
                      G+ ++++ + ++++i  +l +      + ++++++dq +l  vf+g++++l+  yn l +++++  ++     e+++ +Hyi + KPW+d
      EEA22343.1 190 GGLQVVNPSKGTYDKIVAQLGSA-----ATSDYEFADQSLLSDVFYGRWIALPYIYNALKTMRRKGVHDAIWRDESVKNVHYILSPKPWDD 275
                     89999999999999999988887.....334788*****************************7777777777899*************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (313 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       352  (0.019633); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2233.20
//
Query:       EEA22344.1  [L=495]
Description: sucrose transport protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.3e-10   38.2   4.5    6.3e-10   38.2   4.5    3.0  3  MFS_2     MFS/sugar transport protein
    0.00021   20.4   0.5    0.00036   19.7   0.5    1.5  1  PUCC      PUCC protein


Domain annotation for each model (and alignments):
>> MFS_2  MFS/sugar transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.2   4.5     7e-14   6.3e-10      30     238 ..       1     225 [.       1     244 [. 0.84
   2 ?    0.8   0.1     0.015   1.4e+02     129     163 ..     262     296 ..     252     317 .. 0.84
   3 ?   -3.4   5.7       0.3   2.7e+03     289     341 ..     339     389 ..     335     395 .. 0.88

  Alignments for each domain:
  == domain 1  score: 38.2 bits;  conditional E-value: 7e-14
       MFS_2  30 lsaalvglvllvarlvDaitDpivGtlidktstrwGrrrPwlllsaiilavsiillftppelsqs................akfiwllvtyillrilyt 112
                 +s al+++v ++  l+  i+ p++G+ +d+++ rwGrr+P++ +++ ++++ +++l ++ el  s                a++i +++++   +  ++
  EEA22344.1   1 MSKALLAWVWVAGPLTGTIVQPYIGIRSDNCRSRWGRRKPFIAIGGATTVICLLALAWVRELTGSifavfgadhesdtvksASIIGAIILMYCHDFGIN 99 
                 5778999******************************************************9999*************9998888888888889***** PP

       MFS_2 113 lfeipyvslvpvltkdydeRtsltsvr.sflsvlggvlaailafllvlilgglkserkgylifaliialLmllgviivvlgtkervemrkkekteqkek 210
                 +++ ++ ++++  ++  +++ s++++  ++++++  +  a+  + l  i+    + ++ + ++ +i++   +++ ++++++  e++  +k++++ + + 
  EEA22344.1 100 TVQAAMRAYIVDNAPWHQQK-SANAWAsRVSEAASILSYAFGYMNLPEIFPI--LGKTQFQVISVIGSFCLIGSLLVSCIFIEEQRTHDKPRAAVRLST 195
                 *************6666555.5555551566666677778899999999998..888999999999999999************998899999999999 PP

       MFS_2 211 lslleqlkevfrn..raflillllfllaal 238
                 ++ ++++ ++ r+  ++  +++++ ++ ++
  EEA22344.1 196 MNSFGMIWKSARHlpPQIKKVFAIQFASWF 225
                 999999999999832333344444444444 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.015
       MFS_2 129 ydeRtsltsvrsflsvlggvlaailafllvlilgg 163
                  +e t++++  +fl+++  ++++++ +l+v+++++
  EEA22344.1 262 WSEATRIATSAYFLNAVVAFVGSLVLPLMVVAPSQ 296
                 57889999*********************999998 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 0.3
       MFS_2 289 kntyllgalltivllvlvlllqpsnlllflvllviagfgvgvaallpwsmlad 341
                 ++++l++  l +v ++ ++++  s+  ++ ++ +i+g++  v   +p++++a+
  EEA22344.1 339 RRLWLFSHFLFAVCMFSTVFI--SSPGIAALMIAIVGIPWMVTSWAPYAFIAT 389
                 678899999999999999998..99999999999*****99999999999986 PP

>> PUCC  PUCC protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.5     4e-08   0.00036      14     122 ..       4     118 ..       2     202 .. 0.77

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 4e-08
        PUCC  14 avvvavlialpllvapfraliGfrSDtkr.alGwkRvpyiwlGslalalglaiaplalivlsgkgeae.......aaatwaglilaavafllvGlgvsl 104
                 a+++ v +a pl   ++++ iG rSD++r  +G +R p+i  G ++ ++ l +a+  +  l+g+  a        ++  +a+ i a+++     +g+++
  EEA22344.1   4 ALLAWVWVAGPLTGTIVQPYIGIRSDNCRsRWG-RRKPFIAIGGATTVICL-LALAWVRELTGSIFAVfgadhesDTVKSASIIGAIILMYCHDFGINT 100
                 667778899999999**************7777.68899998887776633.2333333344333222212211244444444555555555579**** PP

        PUCC 105 sqTallALladlaeeeer 122
                 +q a+ A ++d a  +++
  EEA22344.1 101 VQAAMRAYIVDNAPWHQQ 118
                 **********99876655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (495 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       708  (0.0394891); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.42
# Mc/sec: 3574.59
//
Query:       EEA22345.1  [L=495]
Description: sucrose transport protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.3e-10   38.2   4.5    6.3e-10   38.2   4.5    3.0  3  MFS_2     MFS/sugar transport protein
    0.00021   20.4   0.5    0.00036   19.7   0.5    1.5  1  PUCC      PUCC protein


Domain annotation for each model (and alignments):
>> MFS_2  MFS/sugar transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.2   4.5     7e-14   6.3e-10      30     238 ..       1     225 [.       1     244 [. 0.84
   2 ?    0.8   0.1     0.015   1.4e+02     129     163 ..     262     296 ..     252     317 .. 0.84
   3 ?   -3.4   5.7       0.3   2.7e+03     289     341 ..     339     389 ..     335     395 .. 0.88

  Alignments for each domain:
  == domain 1  score: 38.2 bits;  conditional E-value: 7e-14
       MFS_2  30 lsaalvglvllvarlvDaitDpivGtlidktstrwGrrrPwlllsaiilavsiillftppelsqs................akfiwllvtyillrilyt 112
                 +s al+++v ++  l+  i+ p++G+ +d+++ rwGrr+P++ +++ ++++ +++l ++ el  s                a++i +++++   +  ++
  EEA22345.1   1 MSKALLAWVWVAGPLTGTIVQPYIGIRSDNCRSRWGRRKPFIAIGGATTVICLLALAWVRELTGSifavfgadhesdtvksASIIGAIILMYCHDFGIN 99 
                 5778999******************************************************9999*************9998888888888889***** PP

       MFS_2 113 lfeipyvslvpvltkdydeRtsltsvr.sflsvlggvlaailafllvlilgglkserkgylifaliialLmllgviivvlgtkervemrkkekteqkek 210
                 +++ ++ ++++  ++  +++ s++++  ++++++  +  a+  + l  i+    + ++ + ++ +i++   +++ ++++++  e++  +k++++ + + 
  EEA22345.1 100 TVQAAMRAYIVDNAPWHQQK-SANAWAsRVSEAASILSYAFGYMNLPEIFPI--LGKTQFQVISVIGSFCLIGSLLVSCIFIEEQRTHDKPRAAVRLST 195
                 *************6666555.5555551566666677778899999999998..888999999999999999************998899999999999 PP

       MFS_2 211 lslleqlkevfrn..raflillllfllaal 238
                 ++ ++++ ++ r+  ++  +++++ ++ ++
  EEA22345.1 196 MNSFGMIWKSARHlpPQIKKVFAIQFASWF 225
                 999999999999832333344444444444 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.015
       MFS_2 129 ydeRtsltsvrsflsvlggvlaailafllvlilgg 163
                  +e t++++  +fl+++  ++++++ +l+v+++++
  EEA22345.1 262 WSEATRIATSAYFLNAVVAFVGSLVLPLMVVAPSQ 296
                 57889999*********************999998 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 0.3
       MFS_2 289 kntyllgalltivllvlvlllqpsnlllflvllviagfgvgvaallpwsmlad 341
                 ++++l++  l +v ++ ++++  s+  ++ ++ +i+g++  v   +p++++a+
  EEA22345.1 339 RRLWLFSHFLFAVCMFSTVFI--SSPGIAALMIAIVGIPWMVTSWAPYAFIAT 389
                 678899999999999999998..99999999999*****99999999999986 PP

>> PUCC  PUCC protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.5     4e-08   0.00036      14     122 ..       4     118 ..       2     202 .. 0.77

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 4e-08
        PUCC  14 avvvavlialpllvapfraliGfrSDtkr.alGwkRvpyiwlGslalalglaiaplalivlsgkgeae.......aaatwaglilaavafllvGlgvsl 104
                 a+++ v +a pl   ++++ iG rSD++r  +G +R p+i  G ++ ++ l +a+  +  l+g+  a        ++  +a+ i a+++     +g+++
  EEA22345.1   4 ALLAWVWVAGPLTGTIVQPYIGIRSDNCRsRWG-RRKPFIAIGGATTVICL-LALAWVRELTGSIFAVfgadhesDTVKSASIIGAIILMYCHDFGINT 100
                 667778899999999**************7777.68899998887776633.2333333344333222212211244444444555555555579**** PP

        PUCC 105 sqTallALladlaeeeer 122
                 +q a+ A ++d a  +++
  EEA22345.1 101 VQAAMRAYIVDNAPWHQQ 118
                 **********99876655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (495 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       708  (0.0394891); expected 358.6 (0.02)
Passed bias filter:                      421  (0.0234815); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.25s 00:00:00.82 Elapsed: 00:00:00.41
# Mc/sec: 3625.74
//
Query:       EEA22346.1  [L=102]
Description: hypothetical protein PMAA_061240 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      8e-17   60.8   0.1    8.9e-17   60.7   0.1    1.0  1  Hydantoinase_B  Hydantoinase B/oxoprolinase


Domain annotation for each model (and alignments):
>> Hydantoinase_B  Hydantoinase B/oxoprolinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.7   0.1     5e-21   8.9e-17     438     515 ..       1      80 [.       1      81 [. 0.89

  Alignments for each domain:
  == domain 1  score: 60.7 bits;  conditional E-value: 5e-21
  Hydantoinase_B 438 vvreieflepevtvsilserrvfapwGlaGGepGargrvvl...nllvrgeeenlggkatvelkagdvlvietpGGGGyGd 515
                     ++reie++ p +++silse+rv++ +Gl+GGepG++g  ++   n  ++ e++n+g+ka ++l+a d ++i++pGGGG+G+
      EEA22346.1   1 MTREIEARIP-MKFSILSEHRVYSLYGLEGGEPGSVGVNYIfkkNAEAQVEKINIGAKAVTSLNARDYIQINSPGGGGWGK 80 
                     579******9.***************************663444444449999***************************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (102 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       387  (0.0215851); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.36u 0.25s 00:00:00.61 Elapsed: 00:00:00.38
# Mc/sec: 802.46
//
Query:       EEA22347.1  [L=165]
Description: hypothetical protein PMAA_061250 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (165 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       495  (0.0276089); expected 358.6 (0.02)
Passed bias filter:                      330  (0.0184059); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.35u 0.26s 00:00:00.61 Elapsed: 00:00:00.38
# Mc/sec: 1296.01
//
Query:       EEA22348.1  [L=581]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.2e-44  152.7  47.7    4.7e-44  150.7  47.2    2.3  1  MFS_1            Major Facilitator Superfamily
    2.3e-11   42.8  25.3    4.4e-11   41.9  25.3    1.4  1  TRI12            Fungal trichothecene efflux pump (TRI12)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  150.7  47.2   5.3e-48   4.7e-44       1     352 [.      79     481 ..      79     482 .. 0.89

  Alignments for each domain:
  == domain 1  score: 150.7 bits;  conditional E-value: 5.3e-48
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlga 99 
                 l++++fl+al+ +i+g+a+p  ++++++ s++ +g+  ++y+l++ ++++ +Gr+   +  ++ +l+++++f lg+l++ +a+++ +l+ +r+++G g 
  EEA22348.1  79 LFITVFLVALDQTIIGTAIP-KITDQFH-SVQDVGWYGSAYFLTSTALQPTYGRIYKIMNVKWAFLAAIFVFELGSLICGVAPNSSTLIGGRAIAGCGV 175
                 79******************.*******.**********************************************88888668888************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 +++f++++++++   p ++r++++gl++a +++++++gpllgg+++++++Wr++fyi+ +++ +a+ +++l l  +++++ +  ++ +           
  EEA22348.1 176 AGIFSGALVILSFSIPLRQRPMVFGLFGAVWGVASVVGPLLGGAFTDHISWRWCFYINLPIGGVAAAIVVLILHLPARKNDKTQTWSQTlleldlvgaa 274
                 *****************************************************************99999999999999999999998899******** PP

       MFS_1 189 ............................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsgl 243
                                                             +++ + +++     +lk++ +w++ i +++f+ +f++++++lp+y+q+v + s +
  EEA22348.1 275 liipaivclllalqwggnkypwsdsriiglfvgfgliailfgisQWKLGDQATL-PPRILKKRTVWSVSIFAVSFGGAFFLFMYYLPIYFQSVKDHS-A 371
                 **************9999999999999999999999999999984444444444.45788888899555555555559*******************.8 PP

       MFS_1 244 llaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavt.ssavllllvlvliGfglgfvfpsllalasdlappeeagtasglf 341
                   +g+ l  + l+++i+++++g l++ +g  ++ l+   +l+++  gl+ +  t  s++ ++   +l+G g+g  f   +++++  +++e     s+++
  EEA22348.1 372 TKSGIDLLPILLATVISSVFFGGLITAVGYYTPFLILSTVLFCIGSGLLTTYSTtISTPKWIGYQILAGAGVGAGFQVPMTAVQTILSQEDIPIGSAAV 470
                 ****9999999999999************977777777777777777777777744444444466667778888888888888888888********** PP

       MFS_1 342 ntagslggalg 352
                 +++++lggal+
  EEA22348.1 471 MFFQNLGGALF 481
                 ********986 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.9  25.3   4.9e-15   4.4e-11      65     552 ..      95     561 ..      35     564 .. 0.69

  Alignments for each domain:
  == domain 1  score: 41.9 bits;  conditional E-value: 4.9e-15
       TRI12  65 salpnilqdvgqsensslfstlwttgqavsilvmgrltdrfgrr.pfvilthilglvgaivgctatkfntllaamtllg..vaagpagasplfvgel.m 159
                 +a+p+i ++    ++ + + + + +  +      gr+   +  +  f+ +  ++  +g+++   a +  tl+   ++ g  va   +ga  ++   + +
  EEA22348.1  95 TAIPKITDQFHSVQDVGWYGSAYFLTSTALQPTYGRIYKIMNVKwAFLAAIFVFE-LGSLICGVAPNSSTLIGGRAIAGcgVAGIFSGALVILSFSIpL 192
                 5666666666666666666555555554455566777666655414444444444.4555655667778888766665510444444444333222224 PP

       TRI12 160 snktkflgllivsipvvvtsglspylgqrlaiqgswrwifyiyiitsaiavllivvwyyppsfaqlhgkkvrkreelakldwigiilvivgvslfllgv 258
                  ++  ++gl+   +  v  s ++p lg  ++   swrw fyi + +  +a  ++v+  + p+ +    k  +  + l  ld +g  l+i  +  +ll +
  EEA22348.1 193 RQRPMVFGLFGA-VWGV-ASVVGPLLGGAFTDHISWRWCFYINLPIGGVAAAIVVLILHLPARK--NDKTQTWSQTLLELDLVGAALIIPAIVCLLLAL 287
                 455556666544.3344.4458*************************************99866..4666777889*********************** PP

       TRI12 259 swggkpnspwnsakviglissglgslvvfalyevygkpvrpivppalfkdtrgfvcillissimgamnlslviiypqqvvnifgsslknweetawms.. 355
                  wgg+ + pw  +++igl+  g g + ++     +    +  +pp ++k    + + ++  s  ga+ l +        + i+  s+k+   t      
  EEA22348.1 288 QWGGN-KYPWSDSRIIGLFV-GFGLIAILFGISQWKLGDQATLPPRILKKRTVWSVSIFAVSFGGAFFLFMYY------LPIYFQSVKDHSATKSGIdl 378
                 ****7.57*********985.888888877778899999*******999877666666667788888775432......34555555555554332200 PP

       TRI12 356 atasfgtgagvvvlgslfhlvrhir.wqilvgalwlt..aflgamssvnrdnknaaialsvlsgfvvawaqditmllvqfittdedlgvafavvaaarp 451
                     + t    v +g l+  v +   + il   l+     +l + s+         i   +l+g  v+   ++ m  vq i ++ed+ +  a    a  
  EEA22348.1 379 LPILLATVISSVFFGGLITAVGYYTpFLILSTVLFCIgsGLLTTYSTTIS--TPKWIGYQILAGAGVGAGFQVPMTAVQTILSQEDIPIGSA----AVM 471
                 23345566666666666666655441444444444321123333333332..345799****************************988765....556 PP

       TRI12 452 fagsiftaafislysnrypkelashlssalrgtdipqasfsslleaaksgrieavkalpgmtteiaavvsramadsytasyanvyyfamalgvipiias 550
                 f+  +  a fis+    + + l+s++ s ++         +s++ +a +  i  v +  g  +e+ avv      +y a   n y +++al  + ++a+
  EEA22348.1 472 FFQNLGGALFISVGQSVFQNGLSSYMQSHVQD------IEPSVIISAGATAIRDVLSKIGKLDELPAVVE-----AYMAGLVNAYRVSLALTCVALVAT 559
                 77777788888888888888888888887654......44788888888889999999999999999985.....678889999999999999999998 PP

       TRI12 551 lc 552
                 l 
  EEA22348.1 560 LF 561
                 85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (581 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1066  (0.0594567); expected 358.6 (0.02)
Passed bias filter:                      611  (0.0340789); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.72u 0.31s 00:00:01.03 Elapsed: 00:00:00.49
# Mc/sec: 3601.19
//
Query:       EEA22349.1  [L=127]
Description: hypothetical protein PMAA_061270 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (127 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       234  (0.0130515); expected 358.6 (0.02)
Passed bias filter:                      232  (0.0129399); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.30s 00:00:00.72 Elapsed: 00:00:00.46
# Mc/sec: 823.02
//
Query:       EEA22350.1  [L=249]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-09   37.6   0.0    4.3e-09   37.1   0.0    1.3  1  DIOX_N    non-haem dioxygenase in morphine synthesis N-termin
  ------ inclusion threshold ------
       0.15   12.1   0.2       0.41   10.7   0.1    1.8  2  VHL_C     VHL box domain


Domain annotation for each model (and alignments):
>> DIOX_N  non-haem dioxygenase in morphine synthesis N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.1   0.0   4.8e-13   4.3e-09       4     100 ..      26     128 ..      19     157 .. 0.78

  Alignments for each domain:
  == domain 1  score: 37.1 bits;  conditional E-value: 4.8e-13
      DIOX_N   4 idlsplsddedraavaeqlreAcrevGffyvvnhg..vpe...elidelfeaareFFalPeeeKeklaksp..sf.rGysrlgeektdgkkldwkesfd 94 
                 i l++l   + +  +ae + +Acr+ Gff++  +g  v e    ++d++++++r+  +l+++eK+k+a+++   f   y+  g  kt+++ +d +e+++
  EEA22350.1  26 IALAKL--VAGDTGEAETVLHACRTLGFFLLDLTGdpVGEkmiVEADAVLDIVRRTMELSLDEKNKFAQDRpnDFrASYKEQGMMKTETGAPDRCEFYN 122
                 555544..456677899*************988772255544556799*******************55532466256********************* PP

      DIOX_N  95 lgtelp 100
                 ++++  
  EEA22350.1 123 VSQDDL 128
                 *99844 PP

>> VHL_C  VHL box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       1.1     1e+04      42      54 ..       9      21 ..       7      22 .. 0.78
   2 ?   10.7   0.1   4.6e-05      0.41      16      52 ..     147     183 ..     145     187 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 1.1
                XXXXXXXXXXXXX CS
       VHL_C 42 dsPnvlkDlqris 54
                 +P+   Dl  i 
  EEA22350.1  9 SQPSFPDDLEPIA 21
                6899999998775 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 4.6e-05
                 HHHHHHH-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       VHL_C  16 qvvRkLVrpedyrrLeIarcLkeeLedsPnvlkDlqr 52 
                 q+ R+   +  +    I r L+ +Le  P+ l+Dlq 
  EEA22350.1 147 QLLRSYLEHGQFALTHILRALETQLELLPDTLRDLQA 183
                 5667777777788889*******************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (249 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       351  (0.0195772); expected 358.6 (0.02)
Passed bias filter:                      333  (0.0185733); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 1792.72
//
Query:       EEA22351.1  [L=200]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (200 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       460  (0.0256568); expected 358.6 (0.02)
Passed bias filter:                      277  (0.0154498); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.24s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 1446.60
//
Query:       EEA22352.1  [L=338]
Description: endoglucanase-5 precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.3e-15   55.1   9.5    5.3e-15   55.1   9.5    3.1  3  CBM_1     Fungal cellulose binding domain
    1.1e-06   28.8   0.6    1.1e-06   28.8   0.6    2.3  2  DPBB_1    Lytic transglycolase


Domain annotation for each model (and alignments):
>> CBM_1  Fungal cellulose binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -9.8   8.3         2   1.8e+04       5       7 ..      70      72 ..      69      93 .. 0.50
   2 ?   -1.7   0.3      0.34     3e+03      13      19 ..     292     298 ..     291     300 .. 0.70
   3 !   55.1   9.5   5.9e-19   5.3e-15       1      29 []     303     331 ..     303     331 .. 0.98

  Alignments for each domain:
  == domain 1  score: -9.8 bits;  conditional E-value: 2
       CBM_1  5 CGG 7 
                CGG
  EEA22352.1 70 CGG 72
                655 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.34
       CBM_1  13 pTtCvsg 19 
                 +TtC s 
  EEA22352.1 292 ATTCSSS 298
                 5888876 PP

  == domain 3  score: 55.1 bits;  conditional E-value: 5.9e-19
       CBM_1   1 lwgQCGGigWtGpTtCvsgatCtyqNeyY 29 
                 l+gQCGGi+WtG+TtCvsg+tC++qN+yY
  EEA22352.1 303 LYGQCGGINWTGATTCVSGSTCKVQNPYY 331
                 7**************************** PP

>> DPBB_1  Lytic transglycolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.3      0.44   3.9e+03       5      17 ..      22      37 ..      12      44 .. 0.64
   2 !   28.8   0.6   1.2e-10   1.1e-06       1      56 [.      54     128 ..      54     138 .. 0.71

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.44
                EEEE-..CCC.-TTSS CS
      DPBB_1  5 sasly..kdg.tacGe 17
                 + +y  ++g ++cG+
  EEA22352.1 22 TTRYYdgQEGaCGCGS 37
                4556654333678876 PP

  == domain 2  score: 28.8 bits;  conditional E-value: 1.2e-10
                 XEEEEEEE-..CCC....-TTSSB--TTS-EEE-SSS-TT-EEEE.TT.--EEEEEEEE----................S CS
      DPBB_1   1 taagsasly..kdg....tacGecyevkcltaahktlplgtycrv.ls.gksvtVtitDrgpf................p 56 
                 taags++l+  +d      +cG+cy+++   +  ++ + g  c + +  g+s++V++t+ +p+                 
  EEA22352.1  54 TAAGSQALFdtNDSswcgGGCGKCYNLTS--TGTSA-CNG--CGEgGVaGESIIVMVTNLCPYngnevwcpsvgaknnyG 128
                 689******754449999********999..22323.333..6666557**************66666655555555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (338 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1393  (0.0776954); expected 358.6 (0.02)
Passed bias filter:                      441  (0.024597); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 2250.68
//
Query:       EEA22353.1  [L=607]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-41  142.0  53.3    2.1e-41  142.0  53.3    1.8  2  MFS_1     Major Facilitator Superfamily
    1.6e-13   50.0  37.5    1.1e-12   47.2  37.5    1.9  1  TRI12     Fungal trichothecene efflux pump (TRI12)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  142.0  53.3   2.4e-45   2.1e-41       1     352 [.     111     514 ..     111     515 .. 0.88
   2 ?   -3.1   0.1      0.32   2.8e+03     237     264 ..     566     592 ..     540     603 .. 0.49

  Alignments for each domain:
  == domain 1  score: 142.0 bits;  conditional E-value: 2.4e-45
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlga 99 
                 l+l++f++al+ +i+++a+p  ++++++ ++  +g+  ++y l+++ ++l++G l + ++ ++v+l++l++f lg++++ +++++  l+ +r+++G+ga
  EEA22353.1 111 LCLSVFCMALDNTIIATAIP-RITDQFN-AVNDVGWYGAAYLLTTCCLQLIFGKLYTFYSVKWVYLTALFIFELGSFVCGITPNSVGLIMGRAVAGIGA 207
                 6899****************.*******.**********************************************666665566669************ PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 +++f++++ ++++ +p  +r++++gl++++++++++ gpl gg++++ + Wr++fyi+ +++++ ++++++++  +  + k ++++ +e          
  EEA22353.1 208 AGIFSGALLIVSRTVPLAQRPMYMGLIGGMWGIASVAGPLMGGAFTDKVTWRWCFYINLPFGAITGLFIIFFFQPPGGKTKAVASTWQEqiklldlegt 306
                 *******************************************************************988999777777777777777789999***** PP

       MFS_1 189 ..............................................kgtgpaplvpawkallkdpvlw.illialllfffgfsglltllplylqevlgl 240
                                                                ++g+ + vp    ++k++ +w ++l+a++ + ++f+++ +++p+++q   g 
  EEA22353.1 307 fffipgviclllalqwggtkypwsdgriialfvlfgvliiafvaiqIWKGELATVP--PRIFKNRNIWgCALYAAFQG-AAFFIFIYYIPIWFQAIKGA 402
                 **********************************9999999999865555555555..99999999**7777777776.5******************* PP

       MFS_1 241 s....glllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllll...vlvliGfglgfvfpsllalasdlappe 332
                 s    g ++++  + +l+lv++  ++l+g l+  lg  ++ +++ ++l+ + +gl+ + + +++   ++   +++ +G+g+g+ +++++++a      +
  EEA22353.1 403 SavrsG-IMNL--PLILSLVAI--SMLSGGLVSYLGYYTPFMIISSILTSVGAGLMTTFNVDTPQSQWIgyqFIFGAGVGFGMQQTMVAVQACLKG--K 494
                 *44444.4444..444444444..55***********99999999999999999999999988888888643444478888888888888888888..9 PP

       MFS_1 333 eagtasglfntagslggalg 352
                   +  ++++++ ++lggal+
  EEA22353.1 495 DIAVGTAIVMFSQTLGGALF 514
                 999999999999***99985 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 0.32
       MFS_1 237 vlglsglllaglllallalvgailalla 264
                  ++ + l  a++++ +++++++i+al +
  EEA22353.1 566 AYNDA-LTNAYYVSVAMSCLTLIGALSI 592
                 33333.3333333333333333334333 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.2  37.5   1.2e-16   1.1e-12      50     488 ..     112     537 ..      92     597 .. 0.77

  Alignments for each domain:
  == domain 1  score: 47.2 bits;  conditional E-value: 1.2e-16
       TRI12  50 slnvvatyfvlqasasalpnilqdvgqsensslfstlwttgqavsilvmgrltdrfgrrp.fvilthilglvgaivgctatkfntllaamtllgv.aag 146
                  l v +  +     a+a+p i ++    ++ + + + + +  +   l++g+l   +  +  ++ +  i+ l   + g t + +  l+   ++ g+ aag
  EEA22353.1 112 CLSVFCMALDNTIIATAIPRITDQFNAVNDVGWYGAAYLLTTCCLQLIFGKLYTFYSVKWvYLTALFIFELGSFVCGITPNSVG-LIMGRAVAGIgAAG 209
                 4455554455556799*************************9**********98887664144455666776667788887765.55556666762444 PP

       TRI12 147 pagasplfvgel..msnktkflgllivsipvvvtsglspylgqrlaiqgswrwifyiyiitsaiavllivvwyyppsfaqlhgkkvrkreelakldwig 243
                     + l+v     ++++  ++gl+   +  ++   ++p +g  ++ + +wrw fyi +   ai+ l+i+ ++ pp  +  +    + +e++  ld  g
  EEA22353.1 210 IFSGALLIVSRTvpLAQRPMYMGLIG-GMWGIASV-AGPLMGGAFTDKVTWRWCFYINLPFGAITGLFIIFFFQPPGGKT-KAVASTWQEQIKLLDLEG 305
                 44445555655423577888888765.55555554.8********************************99999998764.55566677888889**** PP

       TRI12 244 iilvivgvslfllgvswggkpnspwnsakviglissglgslvvfalyevygkpvrpivppalfkdtrgfvcillissimgamnlslviiypqqvvnifg 342
                  ++ i gv  +ll + wgg  + pw   ++i l+    g l++  +     k +   vpp +fk+   + c l  ++  ga  + ++   p     i g
  EEA22353.1 306 TFFFIPGVICLLLALQWGGT-KYPWSDGRIIALFVL-FGVLIIAFVAIQIWKGELATVPPRIFKNRNIWGCAL-YAAFQGAAFFIFIYYIPIWFQAIKG 401
                 *******************7.68*********9975.566766555555569999**********99999987.5778999988888888999999999 PP

       TRI12 343 sslknweetawmsatasfgtgagvvvlgslfhlvrhirwqilvgalwltaflgamssvnrdnknaa.ialsvlsgfvvawaqditmllvqfittdedlg 440
                 +s      +  m+    +   a  ++ g l+  + +    +++ ++  +   g m++ n d  ++  i   ++ g  v++  + tm+ vq     +d+ 
  EEA22353.1 402 ASAV---RSGIMNLPLILSLVAISMLSGGLVSYLGYYTPFMIISSILTSVGAGLMTTFNVDTPQSQwIGYQFIFGAGVGFGMQQTMVAVQACLKGKDIA 497
                 8865...46789999999999999******9999999999999999999999*********97764399****************************** PP

       TRI12 441 vafavvaaarpfagsiftaafislysnrypkelashlssalrgtdipq 488
                 v  a+v  ++ + g++f a    +++n+   ++          +++p 
  EEA22353.1 498 VGTAIVMFSQTLGGALFIAVAENVFANKLVSNV--------IAANLPG 537
                 **************9999988888888754433........3333343 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (607 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1244  (0.0693848); expected 358.6 (0.02)
Passed bias filter:                      630  (0.0351386); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.77u 0.29s 00:00:01.06 Elapsed: 00:00:00.48
# Mc/sec: 3778.70
//
Query:       EEA22354.1  [L=543]
Description: cystathionine gamma-synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      1e-30  106.6   0.0    1.3e-30  106.2   0.0    1.1  1  Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
      0.005   16.1   0.0     0.0075   15.5   0.0    1.4  1  Aminotran_1_2    Aminotransferase class I and II


Domain annotation for each model (and alignments):
>> Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.2   0.0   1.5e-34   1.3e-30      66     381 ..     209     530 ..     201     531 .. 0.85

  Alignments for each domain:
  == domain 1  score: 106.2 bits;  conditional E-value: 1.5e-34
                      T-SEEEEESSHHHHHHH...HHHTTS-T..TEE.EEEESTSSHHHHHHHHHTHHHTTCEEEEESTTSHHHHHHHCCT..TEEEEEEESS-TTTT CS
  Cys_Met_Meta_PP  66 ggeaalavssGmaAiaa...ailallka..Gde.ivvsddlYggtqrllkkvlkklgievkfvdtsdleelekaike..ntklvylEtptnpll 151
                      +++ + ++++Gm+Ai++   ai++l+    G + + v   lY  t+++l+k+ +  +i +     +dl++lek +++    +++y+E p+npll
       EEA22354.1 209 RVDDVTCYPTGMSAISNtslAIRSLFDRqdGIHrVAVFGFLYVDTFKVLSKIHSMECILYGNGTSEDLDALEKDLNNglVIDALYTEFPGNPLL 302
                      567788999*****97622256677765335555667799************************************987899************ PP

                      ----HHHHHHHHHHTT-EEEEEGTTTHTTTS-GGGGT-SEEEEETTTTTTCSSS--EEEEEESSCHHHHHHHHHHH.HHHT-B--HHHHHHHHH CS
  Cys_Met_Meta_PP 152 kvvDiekiaklakkagvlvvvDntfaspllqrplklgaDivvhSaTKylgGhsdvvaGvivvkgkeelkkelkflq.nalGavlspfdawlllr 244
                      + +D+e++ kl +k+g +v+vD t+++ +++  + + +D+++ S TK  +G  +v++G  + + +  + ++lk +  ++  +     da ++ +
       EEA22354.1 303 RSPDLERLYKLSRKHGFVVIVDDTVTTSVNVALFPY-CDVICSSLTKMFSGGCNVMGGSTALNPQSPWYSKLKPAIaKNKPEPYFCLDAIVMEK 395
                      *****************************9976665.9********************************99864414455556678******* PP

                      HHTTHHHHHHHHHHHHHHHHHHHHTSTTEEEEE-T.TSTTSTTHHHHHHHSSSG-SEEEEEESSHHHHHHHHHHC-SSSEECSS-SSSS-EEEE CS
  Cys_Met_Meta_PP 245 GlkTLslRlerhqenAlkvAefLekhpkvekvyYp.glpshpqhelakkqlkgaggvlsFelkseeekakkfvdnlklfslaeslGgvesliel 337
                        +    R+++++ n   v   L+ hp+v +v Yp g +s+  ++ +++   g+g++ s +  +  e+a +f d+l +++   slG   +l  +
       EEA22354.1 396 NSRDFTDRVQKANTNTEMVVDMLKGHPTVDEVFYPkGSSSQDLYNKFRRSEGGYGFLASIRFVTP-EAAIAFHDALDVAK-GPSLGTNFTLCCA 487
                      ***********************************445555668888888888888999999988.78********9865.79****9999887 PP

                      TTTTTTTTSCHHHHHHTTS-TTEEEEE--SS-HHHHHHHHHHHH CS
  Cys_Met_Meta_PP 338 pasmthasipkeereaagvtddliRlsvGiEdvdDliaDlkqal 381
                       +   h s   +  +++gv ++l+R+svGiE  d l + +++al
       EEA22354.1 488 YTLLAHYSEL-DWAAEYGVVEHLVRISVGIECEDLLRNIFNKAL 530
                      7777776644.456889**************7666666566666 PP

>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   8.4e-07    0.0075     110     189 ..     258     326 ..     195     425 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 8.4e-07
                    HHHTTSEEEEEEBEETTTTEE-HHHHHHHHTTHHCTTETEEEEEEESS-TTT--B--HHHHHHHHHHHHHTTEEEEEEET CS
  Aminotran_1_2 110 lrlsggevvryplyseedfhldlealeealkeapegnkktkvilvesphNPtGtvatleeleklldlakkynlllfvDea 189
                     +++ +e++ y     ++ + dl+ale++l++       +  +++e p NP    ++le l kl    +k++++++vD++
     EEA22354.1 258 SKIHSMECILYG----NGTSEDLDALEKDLNN--GLV--IDALYTEFPGNPLLRSPDLERLYKL---SRKHGFVVIVDDT 326
                    455556666666....88899**********9..333..699*********9999999999999...***********85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (543 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       322  (0.0179597); expected 358.6 (0.02)
Passed bias filter:                      317  (0.0176809); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 3729.96
//
Query:       EEA22355.1  [L=549]
Description: uracil permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-92  311.1  50.6    1.3e-92  310.9  50.6    1.0  1  Transp_cyt_pur  Permease for cytosine/purines, uracil, thiami


Domain annotation for each model (and alignments):
>> Transp_cyt_pur  Permease for cytosine/purines, uracil, thiamine, allantoin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  310.9  50.6   7.3e-97   1.3e-92       1     439 [.      33     485 ..      33     486 .. 0.97

  Alignments for each domain:
  == domain 1  score: 310.9 bits;  conditional E-value: 7.3e-97
  Transp_cyt_pur   1 pvpeeeRtwktlnlfsiWlganlnintwvigalglalgLnwwqsvlviivgnligaifvallglaGakyGlpfpilsRasfGirgsllplllrvv 95 
                     p p e+ tw ++n+++++ +   + ++w++g+ ++ +gLnwwq+++vi v+++i+ i++a++++  a y++ fp + R++fG +gs   +  r++
      EEA22355.1  33 PTPPEQQTWHWWNYVTFYWSI--SFTNWTLGSAMIGVGLNWWQAIIVIFVSQFISSIAMAFNSRSAAVYHIGFPCVGRSVFGMWGSYYFVGARAI 125
                     6799*************9975..568********************************************************************* PP

  Transp_cyt_pur  96 iaivwfgvqawiGsealllmlgkifgk.wleigg...ailgtsltelvtffifwvvslvivllgvskirkffviaallvpvaafgfliwalvkae 186
                     +ai+w++vq + G++ ++++l+ ifg+ ++ i++    +  +++ ++++ff +w+v+l++ ++ + ++rkff ++ ++  +a fg+ iwa+++++
      EEA22355.1 126 LAIIWYAVQMYSGAQYMYNILRTIFGHnFTDIPNhlpESASITTPVMLSFFLAWLVHLPFCYFRPYQLRKFFWFKTIVSLPAIFGLFIWAMANTK 220
                     **********************************9999999****************************************************** PP

  Transp_cyt_pur 187 g...Gpvldkavklg.kse.lflsavagvlagfatlilnapDFtryaktkkssvkiqlvavpllftlllligilvaaaakaayganawspldila 276
                     g   G+++ + ++++ +++ ++l+++++ +++ atli+n pD++r+ ++k + v++ql++ p+++tl++ +gil +aa    +g+++w+  d++ 
      EEA22355.1 221 GrlsGGLYAATSASSsTVAwMILAGINSGMGNTATLITNQPDYARWSRSKGAPVWTQLISNPIAVTLSASLGILSTAAVNLKFGTSIWNQWDLMS 315
                     ***96666655444425558889************************************************************************ PP

  Transp_cyt_pur 277 kfdet.......agvllililvalaqlgvnisanllsagldlaallPkkinikrgsliaavialvivpwkllssssklftaflsllavflspvag 364
                      ++++       ++v+l ++  +++ +gvni+an++++g d + l+P +in++rg +i+ ++a +++pwk l+s++k ft+fls ++ f+ +v++
      EEA22355.1 316 LILDNywtssvrFAVFLCAFAWLVQVVGVNIAANMIAFGADSSMLFPSYINMRRGQFIIEILAWIVCPWKILASAAK-FTTFLSGYGLFMASVVA 409
                     *****************************************************************************.***************** PP

  Transp_cyt_pur 365 viiadyfvvrrgylklaalytrr.rgsaYwyrkgvNwravaayivGiaaglvgvagsvgikvvkgaeklfdlsylv 439
                     +++ dyf + +g++ +  ly    ++  Y+y+ gvN +av+ayi+Gia+ ++g+ g+ g  v+  a+   dl++++
      EEA22355.1 410 IMVCDYFLLTKGNIFVPSLYNGTpANKNYYYTHGVNIQAVIAYIIGIALPFPGFCGQLGANVSTAAMHIVDLGWIL 485
                     ********************9888999***********************************************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (549 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       598  (0.0333538); expected 358.6 (0.02)
Passed bias filter:                      199  (0.0110993); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.25s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 3665.08
//
Query:       EEA22356.1  [L=1215]
Description: reverse transcriptase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-34  119.9   0.0    2.3e-34  118.9   0.0    1.5  1  RVT_1     Reverse transcriptase (RNA-dependent DNA polymerase
    5.4e-23   81.9   0.0    1.2e-22   80.8   0.0    1.5  1  AAT       Acyl-coenzyme A:6-aminopenicillanic acid acyl-trans
  ------ inclusion threshold ------
      0.081   13.6   0.1      0.081   13.6   0.1    2.7  3  zf-RVT    zinc-binding in reverse transcriptase


Domain annotation for each model (and alignments):
>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.9   0.0   3.8e-38   2.3e-34       5     221 ..     203     453 ..     199     454 .. 0.92

  Alignments for each domain:
  == domain 1  score: 118.9 bits;  conditional E-value: 3.8e-38
                 T.......S-EEE......-THHHHCTB--...........-------HHHH................HCCHTS--EEEEEEBCCGCCCSBB-GGGGGG CS
       RVT_1   5 g......pgsyRpisllsvdykalnkliakrLkdvl..ekllsenqpgfrpgrstldav...edllkalkkkkkaklllklDlkkaFdsvpleellrkl 92 
                        ++s+Rpislls+++k+l+++ia+r++ ++    ll++n +g r+  s ++a+   ++   ++++++k   l+++D+++a++ v  e+ll++l
  EEA22356.1 203 AkdnyslAKSWRPISLLSTLGKILEAVIAERISYAVetVGLLPTNHFGARKRCSAEQALlllQEEIYKAWRNRKVLSLVSFDVQGAYNGVFKERLLQRL 301
                 355688889***************************77789*********************6666667****************************** PP

                 G-EEET..........................TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T......TEEECTTEEEEEESSHHH......HHHHH CS
       RVT_1  93 tafkvptklinliksflstrsfsvrvnge.eskgryekkglpqGsvlSPllfnlfmnellrelrkrakgvtllrYaDDililskskee......lqell 184
                 +a ++p+k++++i +f s r +++ vng+ +  +   ++glpqGs+lSP+lf +f  +l ++  ++      ++++DD +  ++++++      +q+++
  EEA22356.1 302 KARGIPDKIVQWIDAFCSRRMATILVNGStSELRELPQAGLPQGSPLSPILFLFFNADLVQHKISA--AQGSIAFVDDYTAWVTGPTAesnrsgIQAII 398
                 *****************************444455679***********************99997..58899************99999********* PP

                 HHHHHHHHHTT--BEGGG-EEE.......................ESSEEETTEE CS
       RVT_1 185 eaveewlkesglkinpeKtklvlft.................v.kseevkyLGvt 221
                 +   +w ++sg +++ +Kt +v+ft                 v  +++ k+LGv 
  EEA22356.1 399 NRALDWERRSGATFEGQKTAIVHFTrntdrssstpfvikgklVkPKDSAKILGVV 453
                 *****************************99999999998864799999999985 PP

>> AAT  Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.8   0.0   1.9e-26   1.2e-22      31     217 ..     981    1193 ..     964    1198 .. 0.85

  Alignments for each domain:
  == domain 1  score: 80.8 bits;  conditional E-value: 1.9e-26
                  ..SS--EEEESSSS-SEEEEEETTS-EEEE-TTS-TTT---------HHHHHHH.--SHHHHHHTHHHHTTTS-SEEEEEEETTEEEEEEE-SSS-E CS
         AAT   31 d.sgfaslgyagslpGrtdGiNeaGLavtinllslkklrakGfprafitRllLekcesveeAvellkeipraaginyivldaagnaavveveasskv 126 
                  d +++++l  ag + G   G+N++G+ + +n ++   l+ + +p ++  R +L  +++v+eAv++l+e   a+++n+ ++d +gn a+ve++++  +
  EEA22356.1  981 DyTRLQFLNEAGLV-GKI-GVNSHGVGICMNAIRCGALSTDRLPTHVMCRRVLQYAKTVDEAVAMLDEYGGACSFNLAMADVQGNFATVEITPNGLS 1075
                  34566666667777.999.****************************************************************************98 PP

                  E...........EEEESSEEEEE-SS-S-GGGSSS-....----HHHHHHHHHHHHHHCSSSSB......HHHHHHHT---STTTSSSS-....... CS
         AAT  127 c...........sireanealahtNHfvnetleaen....qnilesSisRlerlqellsqkesa......eeaiellkDredepysvlrr..k..sf 198 
                              +  ++++++ahtNH+  ++ e       ++  + S sRl+r+ el+ +  s+      e +i+ l+D+++ p s++r+      +
  EEA22356.1 1076 VinpvsegdstkVAGKGPNFVAHTNHVMTPPTEFPRgaiyDRPAPNSFSRLARMTELTLEDISQkkaltlESVIDRLSDQKGTPVSICRDkpAnaTG 1172
                  889999999886667777********966555544477889****************98887777999*********************85321134 PP

                  BSSSEEEE..EEE-TTS--EE CS
         AAT  199 kswenTil..talydlaarka 217 
                   ++  T++  ++++d  a+k+
  EEA22356.1 1173 MEKMTTLAtvSMVFDTVAKKV 1193
                  567789986666777777766 PP

>> zf-RVT  zinc-binding in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.2       1.7     1e+04       9      38 ..      10      40 ..       4      46 .. 0.75
   2 ?   13.6   0.1   1.4e-05     0.081      53      80 ..     851     878 ..     837     881 .. 0.78
   3 ?   -2.4   0.0       1.4   8.3e+03      41      71 ..     954     982 ..     950     987 .. 0.67

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1.7
      zf-RVT  9 llrekkekvklakliWkska.ppkvkfflWl 38
                 l+ k + +++ak  W++ + ++++ +  W+
  EEA22356.1 10 QLTPKAKPSPYAKRWWTTDLtQLRCIYTYWR 40
                5667777888999999998877888888886 PP

  == domain 2  score: 13.6 bits;  conditional E-value: 1.4e-05
      zf-RVT  53 rgiesssrCqlCgqeeEtieHlfleCpf 80 
                 r  +++s  + Cgq+ Et+eH +++C++
  EEA22356.1 851 RIGAVDSDLCACGQASETVEHFLFRCTK 878
                 44445777789***************75 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 1.4
      zf-RVT  41 knrlptadnllkrgiesssrCqlCgqeeEti 71 
                 ++rl+t+++ +k++i   + C +  + eE+ 
  EEA22356.1 954 NRRLQTKHMGHKNKIM--GYCEFMPHLEEDY 982
                 5678888888887776..5677766666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1215 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       650  (0.0362541); expected 358.6 (0.02)
Passed bias filter:                      500  (0.0278878); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.82u 0.30s 00:00:01.11 Elapsed: 00:00:00.48
# Mc/sec: 7639.59
//
Query:       EEA22357.1  [L=1275]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.9e-38  131.9   0.2    4.8e-38  131.2   0.2    1.3  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    1.7e-07   31.0   0.0    4.1e-07   29.8   0.0    1.6  1  gag_pre-integrs  GAG-pre-integrase domain
    0.00043   20.4   0.0     0.0011   19.1   0.0    1.7  1  rve              Integrase core domain
  ------ inclusion threshold ------
      0.022   14.3   0.0      0.043   13.3   0.0    1.4  1  RVT_1            Reverse transcriptase (RNA-dependent DNA pol
      0.066   13.1   0.0       0.16   11.9   0.0    1.6  1  Flg_hook         Flagellar hook-length control protein FliK
        0.1   12.9   3.2       0.27   11.5   3.2    1.7  1  Orthopox_F14     Orthopoxvirus F14 protein


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  131.2   0.2   1.6e-41   4.8e-38       9     234 ..     779    1001 ..     770    1007 .. 0.91

  Alignments for each domain:
  == domain 1  score: 131.2 bits;  conditional E-value: 1.6e-41
       RVT_2    9 PkdrkaigsrWvftkkkddl.kevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeeelvvhqldvdsafLnaeldeevyvkqPpGfe 104 
                   k+++ +   W++  k+d++ + vk karlv++G  q    d  +++a  +   s r ++a+aa  +l + q d   af+na+ldee++++  pG+ 
  EEA22357.1  779 AKGKQILDCMWIYVYKQDKKgRLVKCKARLVVRG-DQEKRDDMRDTYAATLAARSFRTFMAIAARFDLELKQYDAVNAFVNAKLDEEIFMRMAPGYR 874 
                  577888999********999899***********.577889******************************************************96 PP

       RVT_2  105 idreeekvykLnkslyGlkqapllWnekidkvLkklgferseaesGlyvrgtgegklivalyvddlliagsdikil..edvkkelakkfklkdlgkv 199 
                     e++k+y+Lnk+lyGl+++pllW+++++++L klgf+  + e    +++     +++  yvdd+++a ++++ l  + + ++l +k++++   ++
  EEA22357.1  875 ---ESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFRAVPHEPCCMLKS----GVMLFFYVDDIVVAYKKSRQLeaNSILNQLRAKYNISGGEDL 964 
                  ...46****************************************999999....78999*********9999877225799*************** PP

       RVT_2  200 skfLGieiaq..eaggiklsladyiakvvkkfeltda 234 
                  + fLG+ i++  ++  i ls+a yi k++k ++ ++a
  EEA22357.1  965 EWFLGMRIIRdrSNKMIWLSQATYIDKIAKLADTQQA 1001
                  ********986568889***********998876655 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.8   0.0   1.4e-10   4.1e-07      19      66 ..     163     214 ..     146     215 .. 0.76

  Alignments for each domain:
  == domain 1  score: 29.8 bits;  conditional E-value: 1.4e-10
  gag_pre-integrs  19 knkssinlWHrRLGHpsfsrlkkLfkkgl...lpglkisk.sevCeaCqlgK 66 
                        k ++n+WH RLGHp+ + lk+L+       l g++++    +Ce+C  +K
       EEA22357.1 163 ERKADANRWHARLGHPGPEVLKHLAGAAKgvrLTGISKGPtTVECESCGTSK 214
                      35899********************8544334555554433559****9988 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   3.7e-07    0.0011       2     116 ..     228     344 ..     227     346 .. 0.86

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 3.7e-07
         rve   2 trpgelwqvDvtvvripdgggkayllvvvddfsrlilaealsdemdastvlalleravarfggve...pervlsDngseytskafrefla.dlgirvsf 96 
                 ++pge++ +D+  ++ ++  g++ l  ++d fs++++ ++++++   + +l++l+ +++++ +     p ++ +Dn  + +  +++ +l+ + +i +++
  EEA22357.1 228 HAPGEHLAIDFHDFAESTMHGEKTLMLITDRFSGFMWDYYMTSH-RGDEILETLKWFLDYLEKAYmisPVKIEMDNEIAKRP-EVKHYLEhEKRIILQP 324
                 89**********777799999***********************.**********99999999879**********976664.5555555157899999 PP

         rve  97 trpgrpqdnGkvErfhrtlk 116
                 ++++    nG +Er   ++k
  EEA22357.1 325 SPAHTQALNGGAERSGAIIK 344
                 99999999999999876666 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   1.4e-05     0.043     117     185 ..     868     950 ..     839     960 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.4e-05
                 .........TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T................TEEECTTEEEEEESSHHH..HHHHHH CS
       RVT_1 117 rv.nge.eskgryekkglpqGsvlSPllfnlfmnellrelrkra..........kgvtllrYaDDililskskee..lqelle 185
                 r+  g  es+++y+ +    G+  SPll++  +++ l +l  ra          +gv l  Y+DDi++++k+  +  ++++l+
  EEA22357.1 868 RMaPGYrESGKIYQLNKALYGLRRSPLLWQKELTSTLIKLGFRAvphepccmlkSGVMLFFYVDDIVVAYKKSRQleANSILN 950
                 44344447899999999999***************9999999999***************************88844444454 PP

>> Flg_hook  Flagellar hook-length control protein FliK
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   5.2e-05      0.16      34      69 ..    1161    1196 ..    1153    1212 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 5.2e-05
                  ETTEEEEEEEE-SCHHHHHHHHTHHHHHHHHHCCTT CS
    Flg_hook   34 rggqlsvqltaenpetrelLeqnlprLreaLaaaGl 69  
                  r +  ++++  +n++t+ lLe+++prLr+ L+   +
  EEA22357.1 1161 RFQTPTLHVYCDNQQTLGLLEKDAPRLRTKLRHVDI 1196
                  55566899**********************987544 PP

>> Orthopox_F14  Orthopoxvirus F14 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   3.2   8.9e-05      0.27      32      70 ..     491     528 ..     480     531 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 8.9e-05
  Orthopox_F14  32 idedditellniltelGcdvdfdedfsdiaddvleslie 70 
                   +  ++it ll  l +lG d dfd++++d+ d + + +++
    EEA22357.1 491 VSTQEITRLLTKL-DLGTDADFDDEYADLIDHITDVVFD 528
                   5667888888776.79***************99887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       530  (0.029561); expected 358.6 (0.02)
Passed bias filter:                      482  (0.0268838); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.84u 0.31s 00:00:01.14 Elapsed: 00:00:00.48
# Mc/sec: 7905.71
//
Query:       EEA22358.1  [L=445]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.081   13.3   3.6        3.4    8.1   0.3    2.5  2  REV1_C           DNA repair protein REV1 C-terminal domain
        0.9    9.3   6.0       0.29   11.0   0.2    2.6  3  Sulfotransfer_4  Sulfotransferase domain


Domain annotation for each model (and alignments):
>> REV1_C  DNA repair protein REV1 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.3    0.0023        21      43      82 ..     147     186 ..     121     188 .. 0.85
   2 ?    8.1   0.3   0.00038       3.4      16      81 ..     206     269 ..     199     278 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0023
      REV1_C  43 avavlkwlrvlleeeeeskeeeageaWekafrevkeavqe 82 
                 ++++  w+++ +  + +++   ++ +W++a+ ++ke+v++
  EEA22358.1 147 IEQIFIWMKQTVSPSYHKTCIAVTANWKEAYINLKEQVNQ 186
                 45677799999998888999999***************96 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.00038
      REV1_C  16 egPneeDvealakyLkkvv..eeerdlekavavlkwlrvlleeeeeskeeeageaWekafre.vkeavq 81 
                  +P  +D+ea  +  ++++  +e + +  a +vl w  + l+       +  ++aW +a++  ++e+++
  EEA22358.1 206 LKPSTRDLEAWITKWEELLleAERKSMVIADDVLDWSTRFLDAI-----RPLDDAWTTAYEItIEEKIE 269
                 57999*****99999999988888********************.....9**********853666665 PP

>> Sulfotransfer_4  Sulfotransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.3     0.064   5.8e+02     125     172 ..     140     185 ..     121     207 .. 0.54
   2 ?   11.0   0.2   3.2e-05      0.29      97     179 ..     210     297 ..     208     300 .. 0.81
   3 ?   -1.8   0.0      0.26   2.3e+03     143     174 ..     368     401 ..     340     436 .. 0.65

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.064
  Sulfotransfer_4 125 lldpllellaklvellralvrrlfgagsdaedeeaakeayeehnervr 172
                      + ++ +++ ++++ +++++v+  ++++    +++++keay + +e+v 
       EEA22358.1 140 WSEQ-KKAIEQIFIWMKQTVSPSYHKT-CIAVTANWKEAYINLKEQVN 185
                      4433.4444555555555555555553.33555555555555555554 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 3.2e-05
  Sulfotransfer_4  97 eRdpekWlksmkktllalrsetls...rllalldpllellaklvellralvrrlfgag.s.daedeeaakeayeehnervrevvpaer 179
                      +Rd e+W ++++++ll++ ++ +     +l + +++l++ ++l +++ ++++  ++++    + +++++++a+++  +++r+  p +r
       EEA22358.1 210 TRDLEAWITKWEELLLEAERKSMViadDVLDWSTRFLDAIRPLDDAWTTAYEITIEEKiEdGTLTRRELANAFRRNLRKIRNRRPSRR 297
                      8**************9999885543447888888899999999999999999999998542456788888899999888888877655 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 0.26
  Sulfotransfer_4 143 lvrrlfgag.s.daedeeaakeayeehnervrev 174
                      l+++l  ++   ++  + +ak++ e+h + v+++
       EEA22358.1 368 LFKNLAPEEfIpRWGPRMRAKKFAEDHPDLVKKI 401
                      4443333332234566667777777777777664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (445 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1113  (0.0620782); expected 358.6 (0.02)
Passed bias filter:                      437  (0.0243739); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.26s 00:00:00.84 Elapsed: 00:00:00.47
# Mc/sec: 2819.64
//
Query:       EEA22359.1  [L=501]
Description: chitinase 3 precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.4e-15   55.9   0.6    4.4e-14   52.9   0.6    2.0  1  Glyco_hydro_18  Glycosyl hydrolases family 18
    2.8e-10   40.0  11.1    2.8e-10   40.0  11.1    3.9  2  CBM_19          Carbohydrate binding domain (family 19)
  ------ inclusion threshold ------
       0.46   10.7   4.8        1.4    9.2   4.8    1.9  1  CBM_14          Chitin binding Peritrophin-A domain


Domain annotation for each model (and alignments):
>> Glyco_hydro_18  Glycosyl hydrolases family 18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.9   0.6   7.4e-18   4.4e-14       2     226 ..      30     291 ..      29     332 .. 0.67

  Alignments for each domain:
  == domain 1  score: 52.9 bits;  conditional E-value: 7.4e-18
                     EEEEEEGGGGGSS.G........C.............SHTTTESEEEEEEE.EEEE..............TTTEEEESSTTHH.........HHH CS
                     xxxxxxxxxxxxx.x........x.............xxxxxxxxxxxxxx.xxxx..............xxxxxxxxxxxxx.........xxx RF
  Glyco_hydro_18   2 vvgYysswesygn.n........y.............lpsaklthiiyaFa.kidg..............engkvvvsdwedl.........gnf 50 
                     +++Y+++++  +  +        +             +++ ++++ i++F+ ki+g              +           +         ++ 
      EEA22359.1  30 IFMYWGQNSFGKLeEeggqkslgFyckmrlmlnavarIDAPEVDVFIISFVtKIFGrggfpevnfanagnN-----------CttipgtgllKCP 113
                     67888766655433355544444157777777777777799999999999823444776655444444331...........2444555553344 PP

                     HHHHHHHHHTSTT-EEEEEEEETTT.TTHHHHHHTSHHHHHHHHHHHHHHH.....HHCT............-SEEEEEES-TTTSTCHHHHHHH CS
                     xxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxx.....xxxx............xxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18  51 eqlkklkkkknpgvkvllsiGGwtd.ssgfslaastdasrkkfadsvvsll.....rkyg............fDGiDidweypggnpedkenyta 127
                     + + ++ + ++ g+ vlls+GG+t+ ++gfs+  s    +k+ a  +++l+     +  +            +DG+D+d+e      +d++n + 
      EEA22359.1 114 QIAEDIMTCQALGKTVLLSLGGGTYqEGGFSNEIS----AKNSAILLWNLFgppnpN--NnfyeyrpfldalVDGFDFDFE-N----QDMHNTVP 197
                     444555566666************95669998876....567777777777666540..35555668999*9*********.2....58****** PP

                     HHHHHHHHHH.HHHHHTSTTCEEEEEEESSHHHHHHHCHHHHHHHHT..SEEEEETTTSSSTTSSBE--SS-SSB..TCSSHHHHH.HHHH.HTT CS
                     xxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxx.xxxx.xxx RF
  Glyco_hydro_18 128 llkelreald.kakategkkllLsaavpasasdlskgydlpkiakyl..DyvnvmtYDfhgswdnvtghhaplyd..aslnvdeav.keyl.kag 215
                     ++++lr+ +  +    +  ++ L++a+++  +d  + +++ + +  +  D v v++Y+ +       g +a + +  ++ n ++ + ++++ + +
      EEA22359.1 198 FAQALRQLFLtD----TSHHYFLTVAPQCVFPDR-ANDEMLDGN--VwfDAVLVQFYNNYC------GVNAFVPGapQQPNFNFDTwNTWAdNIS 279
                     *******66634....4799*************3.344555544..445********6666......5555555544345555555478997778 PP

                     --GG.GEEEEEE CS
                     xxxx.xxxxxxx RF
  Glyco_hydro_18 216 vpak.klvlGvp 226
                     ++++ k++lGv 
      EEA22359.1 280 LNPNvKIILGVL 291
                     877779999986 PP

>> CBM_19  Carbohydrate binding domain (family 19)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?  -36.0  38.5         3   1.8e+04       2       2 ..     377     377 ..     354     429 .. 0.64
   2 !   40.0  11.1   4.7e-14   2.8e-10       1      58 [.     430     484 ..     422     487 .. 0.83

  Alignments for each domain:
  == domain 1  score: -36.0 bits;  conditional E-value: 3
      CBM_19   2 t 2  
                 t
  EEA22359.1 377 T 377
                 1 PP

  == domain 2  score: 40.0 bits;  conditional E-value: 4.7e-14
      CBM_19   1 itttalatassalfsllvanrsCssqskvaCtadGkYavCdyGkWvvasCPsGvvCls 58 
                 +ttt+ +ta     +++v +  C +   +aC    ++ vC++G+Wv  sCP+G +C+ 
  EEA22359.1 430 TTTTTTSTA--PSITCPVPGGPCPTDGVYACAG-NRFGVCNHGQWVFESCPPGLICVQ 484
                 344444444..4578999*************75.59********************97 PP

>> CBM_14  Chitin binding Peritrophin-A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   4.8   0.00023       1.4       1      47 [.     450     494 ..     450     501 .] 0.74

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00023
      CBM_14   1 CagkedglfadptdCskYyvCsngepveftCpeglvFde..etqtCdyp 47 
                 C+  +dg +a     +++ vC++g++v ++Cp+gl+  +  +   Cd+p
  EEA22359.1 450 CP--TDGVYAC--AGNRFGVCNHGQWVFESCPPGLICVQagSGVYCDHP 494
                 66..6666666..5599*****************986554444455555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (501 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       839  (0.0467957); expected 358.6 (0.02)
Passed bias filter:                      426  (0.0237604); expected 358.6 (0.02)
Passed Vit filter:                       110  (0.00613531); expected 17.9 (0.001)
Passed Fwd filter:                        37  (0.0020637); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.84u 0.33s 00:00:01.17 Elapsed: 00:00:00.48
# Mc/sec: 3125.83
//
Query:       EEA22360.1  [L=428]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.2e-06   28.7   0.2    1.2e-06   28.7   0.2    2.1  2  Retrotrans_gag  Retrotransposon gag protein
    3.8e-05   23.5   0.0      7e-05   22.7   0.0    1.4  1  DUF4939         Domain of unknown function (DUF4939)
  ------ inclusion threshold ------
      0.055   13.6   0.6      0.095   12.8   0.6    1.4  1  zf-CCHC         Zinc knuckle
       0.18   12.3   9.0      0.093   13.2   6.2    1.8  2  Fez1            Fez1
       0.24   11.2  17.0      0.043   13.7   9.8    2.7  3  BBP1_C          Spindle pole body component BBP1, C-terminal
       0.28   11.7   6.9        3.6    8.1   1.0    2.5  2  FAM167          FAM167
       0.28    9.9   5.1       0.44    9.3   5.1    1.4  1  ALMT            Aluminium activated malate transporter
       0.41   11.0   4.7       0.89    9.9   4.7    1.5  1  Phage_Gp23      Protein gp23 (Bacteriophage A118)
       0.87    8.6   7.2       0.45    9.6   4.1    2.0  2  Atg14           Vacuolar sorting 38 and autophagy-related sub
       0.92    9.4   7.6        1.3    8.9   6.5    1.8  1  DUF2570         Protein of unknown function (DUF2570)
        1.7    9.2  14.4       0.91   10.0   8.4    2.6  2  APG6_N          Apg6 coiled-coil region
        2.3    7.9  15.1       0.17   11.6   7.6    2.3  2  TAF4            Transcription initiation factor TFIID compone
        2.4    8.0   7.2       0.85    9.4   3.5    2.0  2  USP8_interact   USP8 interacting


Domain annotation for each model (and alignments):
>> Retrotrans_gag  Retrotransposon gag protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.5       2.8   3.9e+03      56      56 ..      81      81 ..      40     124 .. 0.58
   2 !   28.7   0.2   8.6e-10   1.2e-06       4      95 ..     188     278 ..     185     279 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 2.8
  Retrotrans_gag 56 l 56
                     
      EEA22360.1 81 Q 81
                    1 PP

  == domain 2  score: 28.7 bits;  conditional E-value: 8.6e-10
  Retrotrans_gag   4 stslegaAkswlkslvarsida.sesWkdlkkaflktflpserkdqleeelsslrQgtesvreYvtrfktladqldevlteeakiekflaGLn 95 
                        l+g+A++ ++++   + d+ ++  k++ + + + f  +++++ + e+l++l+Q+++ +  Y+ +f+ l+ +++   ++e k   +l+GL 
      EEA22360.1 188 YALLDGNAATRMTPFMNATNDSrFTKMKEFYDLLERSFGITNKHEYALEQLKQLKQKNQEFVVYLSEFENLIVYCN--YSDEGKKDLLLQGLS 278
                     568999999999999888877779999*************************************************..999999999999996 PP

>> DUF4939  Domain of unknown function (DUF4939)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   0.0   5.1e-08     7e-05      19     109 ..     139     230 ..     123     233 .. 0.87

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 5.1e-08
     DUF4939  19 krrwrnpipfpetfdGdtdrlpefivqtlsymlvdektfssdalkvtflitrltGealewvlpyik.kdspllndyraflaemkrvfGweed 109
                 ++     +p p++f+Gd  ++  fi q       d ++f s+   +    ++l G+a   + p+++ ++   + + + f + + r fG+ ++
  EEA22360.1 139 TESKAEKVPNPDKFSGDRLKVDTFIAQLKNKFTADADKFPSERHMLSHAYALLDGNAATRMTPFMNaTNDSRFTKMKEFYDLLERSFGITNK 230
                 55566789********************************************************9734566788999999999999998765 PP

>> zf-CCHC  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.6   6.9e-05     0.095       2      18 .]     388     404 ..     387     404 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 6.9e-05
                 CTSSSSSSSSTTTTSTS CS
     zf-CCHC   2 kCynCGepGHiardCpk 18 
                  Cy+CG+  H++  Cp+
  EEA22360.1 388 LCYYCGSKDHLKLACPE 404
                 5*********9988885 PP

>> Fez1  Fez1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   6.2   6.7e-05     0.093      30     164 ..      40     183 ..      20     186 .. 0.56
   2 ?   -1.4   0.0         2   2.7e+03      87      99 ..     236     248 ..     203     313 .. 0.62

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 6.7e-05
        Fez1  30 lseivalkaqlrelrakleekeeeikeleesleektlelevcenelqrk.......kseaellrekvekleeelkelreelselsleeeeaa....... 114
                 ++  v+l +q  +  + +++ ++ei++++++ +++++e+ +  +e ++          +++  ++ + + ++ ++e+++++ ++       +       
  EEA22360.1  40 AEQRVQLITQRTDHDKLVSDLNQEISNVNDRNRSQQAEISQQRAEHAKLlsdldreMRKVNERNDWLAQHQNSTEEVKNAVVDA-------Mrsivtes 131
                 334455555555555556666666666666666666665555555555522222223333333333333333333333333332.......24445555 PP

        Fez1 115 ....lesdeakaqr.qeaeeleelkreverlraeLkeerqkkeeqassFeqERrt 164
                     ++ +e+ka++  + ++ +  + +v+   a+Lk++  +    a++F +ER++
  EEA22360.1 132 ggirVNHTESKAEKvPNPDKFSGDRLKVDTFIAQLKNKFTA---DADKFPSERHM 183
                 77775666666655156788999999999999999887666...56679999986 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 2
        Fez1  87 ekvekleeelkel 99 
                 e++++l+++ +e+
  EEA22360.1 236 EQLKQLKQKNQEF 248
                 3333333333322 PP

>> BBP1_C  Spindle pole body component BBP1, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   9.8   3.1e-05     0.043      78     171 ..      27     118 ..      23     131 .. 0.85
   2 ?   -2.1   0.2       2.1   2.8e+03      74      98 ..     236     260 ..     211     283 .. 0.66
   3 ?    1.0   0.0      0.24   3.3e+02       5      26 ..     297     318 ..     294     324 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 3.1e-05
      BBP1_C  78 kiskesldlqskianlekqlvdqaiekdreikkleeklldlelrnkeleekreidkikYesrikdLerqllereneikdtssssnafstseyrk 171
                 +++   l+lq +ia+ + ql+ q  + d+  ++l++++++++ rn+  +++  +++++  + ++dL+r++++ +++  ++   +++ st+e ++
  EEA22360.1  27 QLARAVLQLQTTIAEQRVQLITQRTDHDKLVSDLNQEISNVNDRNRSQQAEISQQRAEHAKLLSDLDREMRKVNER--NDWLAQHQNSTEEVKN 118
                 56677789*************************************************************9999766..5555565556555544 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 2.1
      BBP1_C  74 qeLkkiskesldlqskianlekqlv 98 
                 ++Lk++ ++++++   +++ e+ +v
  EEA22360.1 236 EQLKQLKQKNQEFVVYLSEFENLIV 260
                 3566666666555555555555555 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 0.24
      BBP1_C   5 eYlelldkldkNsreLedlkkd 26 
                 + + ll+kld N r +++l+ d
  EEA22360.1 297 DLVTLLSKLDSNIRLIKSLNGD 318
                 56789*************9977 PP

>> FAM167  FAM167
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   1.0    0.0026       3.6       7      47 ..      27      69 ..      24      76 .. 0.84
   2 ?    6.6   0.8    0.0081        11      18      59 ..      72     113 ..      67     125 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0026
      FAM167  7 qlarqLlrlrseikklkveqsce..ehkemLddatleleeeee 47
                qlar  l+l+  i + +v+ + +  +h +++ d++ e+ + ++
  EEA22360.1 27 QLARAVLQLQTTIAEQRVQLITQrtDHDKLVSDLNQEISNVND 69
                8*************999998776337*********99988765 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0081
      FAM167  18 eikklkveqsceehkemLddatleleeeeelsdllvdlplss 59 
                 + ++  + q  +eh+++L d+  e+ + +e +d l +   s+
  EEA22360.1  72 RSQQAEISQQRAEHAKLLSDLDREMRKVNERNDWLAQHQNST 113
                 55788899********************99999877765554 PP

>> ALMT  Aluminium activated malate transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   5.1   0.00032      0.44     278     378 ..      57     155 ..      24     250 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00032
        ALMT 278 hgcilseiqapeelrkkfkeelqrvslesakvlrelaesvkkmkklskveellkevkvaaeeLqskl.dskskLlvnsekweaakkkekaeeveekkee 375
                  + +++ei   ++ ++  ++e+ +   e ak+l++l  +   m+k ++ ++ l++ + ++ee+++++ d    ++++s   + +++++kae+v +  + 
  EEA22360.1  57 VSDLNQEISNVNDRNRSQQAEISQQRAEHAKLLSDLDRE---MRKVNERNDWLAQHQNSTEEVKNAVvDAMRSIVTESGGIRVNHTESKAEKVPNPDKF 152
                 455677887778888888888888888888888888765...555555566899999999999999878877777788776666666666665554444 PP

        ALMT 376 eke 378
                 + +
  EEA22360.1 153 SGD 155
                 433 PP

>> Phage_Gp23  Protein gp23 (Bacteriophage A118)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   4.7   0.00064      0.89      46     107 ..      58     122 ..      28     131 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00064
  Phage_Gp23  46 iemkeerekkeekrekkeke...skeekdktissvdkskrlldkqndliksekkaidelskslvk 107
                  ++ +e + ++++++ ++ e    + e+ k++s +d++ r ++ +nd + +++++++e+ +++v 
  EEA22360.1  58 SDLNQEISNVNDRNRSQQAEisqQRAEHAKLLSDLDREMRKVNERNDWLAQHQNSTEEVKNAVVD 122
                 45666666666665555555211356889******************************888875 PP

>> Atg14  Vacuolar sorting 38 and autophagy-related subunit 14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   4.1   0.00033      0.45      66     130 ..      47     118 ..      16     147 .. 0.57
   2 ?   -1.3   0.1      0.64   8.8e+02      29      60 ..     215     246 ..     206     265 .. 0.74

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00033
       Atg14  66 kakleelksliadlrerlqelkdklsqlkkeieekkkklaklsdklk.......kRrsdleslqneleerrk 130
                  ++  +  +l++dl++++++++d+ +++++ei +++++ akl ++l        +R+  l+ +qn+ ee ++
  EEA22360.1  47 ITQRTDHDKLVSDLNQEISNVNDRNRSQQAEISQQRAEHAKLLSDLDremrkvnERNDWLAQHQNSTEEVKN 118
                 222223333445555555555555555555555555555555555553333333555555555555555444 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.64
       Atg14  29 erlaklksekeslkkkiekalegkeeaeqled 60 
                 ++ ++l+++++ + +k e ale+ ++ +q+++
  EEA22360.1 215 KEFYDLLERSFGITNKHEYALEQLKQLKQKNQ 246
                 56778888899999999999998884444444 PP

>> DUF2570  Protein of unknown function (DUF2570)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   6.5   0.00092       1.3      23      82 ..      62     121 ..      55     144 .. 0.87

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00092
     DUF2570  23 qkidsLraenkaqaqlieeqqkanqrLteqLeqerqavekqqkianelkakveeekeevk 82 
                 q+i +++  n++q+  i +q++   +L ++L+ e   v++ +    + ++  ee k+ v 
  EEA22360.1  62 QEISNVNDRNRSQQAEISQQRAEHAKLLSDLDREMRKVNERNDWLAQHQNSTEEVKNAVV 121
                 789******************99****************999988888888888888764 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   8.4   0.00066      0.91      52     129 ..      46     123 ..      25     127 .. 0.86
   2 ?    2.1   0.1      0.19   2.6e+02      63      79 ..     231     247 ..     197     287 .. 0.69

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00066
      APG6_N  52 leeeleklekeeeelleeLkelekereeleaelaaleeelealeeeeerfwreynelqlelleleeeldsleaqyeha 129
                 l  +  + +k  ++l +e+ ++ + +++ +ae++++++e+++l  + +r++r+ ne +  l+++++  + +++++ +a
  EEA22360.1  46 LITQRTDHDKLVSDLNQEISNVNDRNRSQQAEISQQRAEHAKLLSDLDREMRKVNERNDWLAQHQNSTEEVKNAVVDA 123
                 5555556667778999********************************************************998766 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.19
      APG6_N  63 eeelleeLkelekeree 79 
                  e +le+Lk+l+++++e
  EEA22360.1 231 HEYALEQLKQLKQKNQE 247
                 33344444444444333 PP

>> TAF4  Transcription initiation factor TFIID component TAF4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   7.6   0.00012      0.17      87     180 ..      32     125 ..      26     129 .. 0.81
   2 ?    0.0   0.8      0.41   5.7e+02     205     225 ..     330     350 ..     313     391 .. 0.47

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00012
        TAF4  87 LltklivlskhRrrgekskkrtesltsdvrkqLrelaqkekeeeekrqakRieereglekaakdrskgedeeekklkaketakevqkeedekar 180
                  l+  + ++++R++ +++++ +++l+sd  +++ +++ +++ ++    ++R+e+++ l   +++  k+++ ++  ++ +++  ev+++  +++r
  EEA22360.1  32 VLQLQTTIAEQRVQLITQRTDHDKLVSDLNQEISNVNDRNRSQQAEISQQRAEHAKLLSDLDREMRKVNERNDWLAQHQNSTEEVKNAVVDAMR 125
                 6777799************************************999999999988888777776666666666555555666677776666666 PP

  == domain 2  score: 0.0 bits;  conditional E-value: 0.41
        TAF4 205 agsgsgggksgaskssssggk 225
                  +s+ ++g+sg+s++ ++g++
  EEA22360.1 330 GSSQRNSGNSGNSSNGNAGSQ 350
                 111122222222222222222 PP

>> USP8_interact  USP8 interacting
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.1      0.64   8.8e+02       7      34 ..      26      53 ..      23      57 .. 0.80
   2 ?    9.4   3.5   0.00062      0.85       4      80 ..      55     133 ..      52     137 .. 0.82

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.64
  USP8_interact  7 qkqqqkiaelkkevaeqkqqlseqkrel 34
                    + ++ + +l++++aeq+ ql +q+ + 
     EEA22360.1 26 AQLARAVLQLQTTIAEQRVQLITQRTDH 53
                   5667788899999999999999998765 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.00062
  USP8_interact   4 elvqkqqqkiaelkkevaeqkqqlseqkre.lellkeyiralrstnpvlraladql.erdevlrWveslklarvtrWGg 80 
                    +lv + +q+i++++++ ++q+ ++s+q+ e  +ll ++ r +r++n+    la++  +++ev + v    ++ vt+ Gg
     EEA22360.1  55 KLVSDLNQEISNVNDRNRSQQAEISQQRAEhAKLLSDLDREMRKVNERNDWLAQHQnSTEEVKNAVVDAMRSIVTESGG 133
                    689999*********************988357999**********998888766635578887766666667777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (428 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2204  (0.122929); expected 358.6 (0.02)
Passed bias filter:                      869  (0.048469); expected 358.6 (0.02)
Passed Vit filter:                       109  (0.00607954); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.75u 0.33s 00:00:01.08 Elapsed: 00:00:00.50
# Mc/sec: 2553.00
//
Query:       EEA22361.1  [L=686]
Description: retrovirus polyprotein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.1e-33  115.6   0.0    2.3e-33  114.6   0.0    1.6  1  RT_RNaseH    RNase H-like domain found in reverse transcripta
    2.1e-30  104.7   0.0    6.2e-30  103.2   0.0    1.8  2  RT_RNaseH_2  RNase H-like domain found in reverse transcripta
    3.5e-21   75.7   0.1    7.6e-21   74.6   0.1    1.6  1  RVT_1        Reverse transcriptase (RNA-dependent DNA polymer


Domain annotation for each model (and alignments):
>> RT_RNaseH  RNase H-like domain found in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.6   0.0   3.9e-37   2.3e-33       2     105 .]     488     593 ..     487     593 .. 0.98

  Alignments for each domain:
  == domain 1  score: 114.6 bits;  conditional E-value: 3.9e-37
                 TTS-EEEEEEECTEEEEEEEEEETTE..EEEEEEEEEE--HHHHTS-HHHHHHHHHHHHHHHHHHHHTS.--.EEEE-SS--TTTTT----.---HHHH CS
   RT_RNaseH   2 pskpfiletDAsddgigavLsqreedgeerpiafaSrklsgaernystiekellAivaalkkfrhylqg.rk.ftvitDhknlkyllskkslngrlarW 98 
                  +k++i+e+D+sd+++g+vLsq +++g   p+af+S+   +ae ny++++kel+Ai+ a++++r+ lqg ++ ++vitDhknl+y+++kk ln+r+arW
  EEA22361.1 488 WDKRCIVEVDSSDYVTGGVLSQYNDNGDLWPVAFFSKMHAPAECNYEIYDKELMAIIRAFEEWRPELQGnPHpIEVITDHKNLEYFTQKKLLNRRQARW 586
                 57999****************************************************************9889************************** PP

                 HHHC-XX CS
   RT_RNaseH  99 aleLsey 105
                 a++Ls++
  EEA22361.1 587 AEFLSQF 593
                 *****98 PP

>> RT_RNaseH_2  RNase H-like domain found in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0      0.97   5.8e+03      58      74 ..     371     387 ..     370     392 .. 0.80
   2 !  103.2   0.0     1e-33   6.2e-30       1      97 [.     462     558 ..     462     563 .. 0.97

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.97
  RT_RNaseH_2  58 iafaSrklskaernyst 74 
                  i  +S++ls+ +r+  +
   EEA22361.1 371 ILIFSKTLSEYKRHVRQ 387
                  5689*****99998766 PP

  == domain 2  score: 103.2 bits;  conditional E-value: 1e-33
  RT_RNaseH_2   1 WteeqekafeklkealtsapvLahpdpdkpfiletDaSdtgigavLsqedddgkerpiafaSrklskaernysttekellAivwalkkfrhyllgrk 97 
                  Wt e+++af++lk+a+t ap+L+ ++ dk +i+e+D+Sd+  g+vLsq +d+g + p+af+S+   +ae ny++++kel+Ai++a++++r+ l+g++
   EEA22361.1 462 WTGECQEAFDTLKTAFTIAPILKTFKWDKRCIVEVDSSDYVTGGVLSQYNDNGDLWPVAFFSKMHAPAECNYEIYDKELMAIIRAFEEWRPELQGNP 558
                  ****************************************************99****************************************954 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.6   0.1   1.3e-24   7.6e-21       2     205 ..     259     406 ..     258     424 .. 0.96

  Alignments for each domain:
  == domain 1  score: 74.6 bits;  conditional E-value: 1.3e-24
                 E-TT.S-EEE.......-THHHHCTB--.........-------HHHH.............HCCHTS--EEEEEEBCCGCCCSBB-GGGGGGG-EEET. CS
       RVT_1   2 pKkgpgsyRp.isllsvdykalnkliakrLkdvlekllsenqpgfrpgrstldavedllkalkkkkkaklllklDlkkaFdsvpleellrkltafkvpt 99 
                 +K+g g++R+ +     dy+ ln++++k           +++p +++              l+  ++a++++klD+  aF++ + ++ ++ +taf+++ 
  EEA22361.1 259 RKPG-GGVRIcV-----DYRGLNEITKK---------NRYPIPLIQET-------------LQMLTRARYFTKLDIIAAFNKLRIAAGDEWKTAFRTR- 328
                 6999.*****55.....***********.........***********.............7789*********************************. PP

                 ........................TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T......TEEECTTEEEEEESSHHHHHHHHHHHHHHHHHTT--B CS
       RVT_1 100 klinliksflstrsfsvrvngeeskgryekkglpqGsvlSPllfnlfmnellrelrkrakgvtllrYaDDililskskeelqelleaveewlkesglki 198
                                          g++e+ ++ + ++++P+ ++ ++n++l+e+       ++++Y+DDili+sk+ +e +++++ v e+lkesgl+ 
  EEA22361.1 329 ------------------------FGLFESLVMNFRLTNAPASWQNYINNILKEYLDD----FVCAYMDDILIFSKTLSEYKRHVRQVLEKLKESGLQC 399
                 ........................9*******************************95....9************************************ PP

                 EGGG-EE CS
       RVT_1 199 npeKtkl 205
                 n +K+++
  EEA22361.1 400 NINKISI 406
                 ****976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (686 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       466  (0.0259914); expected 358.6 (0.02)
Passed bias filter:                      426  (0.0237604); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.66u 0.30s 00:00:00.96 Elapsed: 00:00:00.49
# Mc/sec: 4201.45
//
Query:       EEA22362.1  [L=385]
Description: retrovirus polyprotein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-13   50.0   2.3    3.4e-12   46.1   4.3    2.1  2  Chromo    Chromo (CHRromatin Organisation MOdifier) domain
  ------ inclusion threshold ------
       0.15   12.2   0.5       0.31   11.2   0.5    1.5  1  DUF5457   Family of unknown function (DUF5457)


Domain annotation for each model (and alignments):
>> Chromo  Chromo (CHRromatin Organisation MOdifier) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0      0.54   4.8e+03      17      27 ..     148     164 ..     139     166 .. 0.67
   2 !   46.1   4.3   3.8e-16   3.4e-12       1      54 []     269     319 ..     269     319 .. 0.96

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.54
                 C......EEEEEEETTS CS
      Chromo  17 e......leYlVKWkgl 27 
                        +e+lV  +++
  EEA22362.1 148 AhslaqiHEFLVDHMSY 164
                 24445568999988887 PP

  == domain 2  score: 46.1 bits;  conditional E-value: 3.8e-16
                 EEEEEEEEEEEETTEECEEEEEEETTSTGGGTEEEEGGGCSSHSHHHHHHHHHH CS
      Chromo   1 yeVerIidhrtdkdgleleYlVKWkglpysentWEpeenlekcfqelideFkkr 54 
                 y V +I+d++++ d+   eYlV W g++ +++tWEp ++le+  +e+id+F++r
  EEA22362.1 269 YDVKEILDSQVRNDKI--EYLVWWDGYDIEQSTWEPLDHLENA-EEKIDQFHER 319
                 679*************..***********************99.888*****97 PP

>> DUF5457  Family of unknown function (DUF5457)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.5   3.5e-05      0.31      34      69 ..     261     298 ..     259     318 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 3.5e-05
     DUF5457  34 ikdlkvtErqvrevLdwLVkkkkvlekl..gkYqldkv 69 
                 i++ + tE++v+e+Ld  V+++k+++ +  + Y +++ 
  EEA22362.1 261 IEENDETEYDVKEILDSQVRNDKIEYLVwwDGYDIEQS 298
                 6677789*****************98654488888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (385 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       457  (0.0254894); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2774.05
//
Query:       EEA22363.1  [L=138]
Description: hypothetical protein PMAA_061410 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (138 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       217  (0.0121033); expected 358.6 (0.02)
Passed bias filter:                      208  (0.0116013); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.33u 0.22s 00:00:00.55 Elapsed: 00:00:00.35
# Mc/sec: 1172.15
//
Query:       EEA22364.1  [L=281]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.6e-07   32.1   0.1    3.3e-07   31.1   0.1    1.5  1  2OG-FeII_Oxy_3  2OG-Fe(II) oxygenase superfamily


Domain annotation for each model (and alignments):
>> 2OG-FeII_Oxy_3  2OG-Fe(II) oxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.1   0.1   1.8e-11   3.3e-07       2      91 ..     145     269 ..     144     272 .. 0.76

  Alignments for each domain:
  == domain 1  score: 31.1 bits;  conditional E-value: 1.8e-11
                     EEEEE-TT-EEEEE-SS--.--TT.-.EEEEEEEEE....E.T-B--EEE............................................. CS
  2OG-FeII_Oxy_3   2 qvlrygegqeykpHvDnfe.keegsgqrrltvllyLnekes.eeGGelelyekdk.....................................eav 57 
                      +l+y  g++++pH+D ++ + +gs+   +t+ lyL+   + eeG +le + +++                                     +av
      EEA22364.1 145 RFLKYVGGEYFRPHCDGNYrTPDGSEISYYTIQLYLS--GEgEEGQDLEEFARRQkkelnskgiktedkegadeekllggatsfmpsweladQAV 237
                     5789988899******999766666778999999**5..22356666555555445566666666666777777778888888888888888999 PP

                     ..---TT-EEEEE-..B-TEEE--B.-SS-EEEE CS
  2OG-FeII_Oxy_3  58 kikpkkgrlvlFesdellpHevlpvtkggeRlsl 91 
                     ++ pk gr+++F+ ++l +H++  v   g+++++
      EEA22364.1 238 RVWPKTGRVLVFQQNNL-WHGGDSVYG-GTKYTV 269
                     999***********877.7******65.599987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (281 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       357  (0.0199119); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.22s 00:00:00.68 Elapsed: 00:00:00.39
# Mc/sec: 2138.15
//
Query:       EEA22365.1  [L=283]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-14   54.8   0.2    1.6e-14   54.2   0.2    1.3  1  DUF3328   Domain of unknown function (DUF3328)


Domain annotation for each model (and alignments):
>> DUF3328  Domain of unknown function (DUF3328)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.2   0.2     9e-19   1.6e-14      19     219 ..      72     271 ..      55     272 .. 0.58

  Alignments for each domain:
  == domain 1  score: 54.2 bits;  conditional E-value: 9e-19
     DUF3328  19 llllllllllilssllsssekkaak......kkspsspspaldaieyelkqfk....lgskeapsiyrgepspevdaaWddll..kleailipree.lr 104
                 + l+lll lli+  l+   ++k ++         +     ++   ++  ++++    + +k  p++  ++++ ev ++Wd l+   +++il+p+ + ++
  EEA22365.1  72 WSLILLLQLLIIVLLVRPVPEKGDNcilsgkEGFVETGDDINGLYKTLSHTYTflkpEEDKYVPNMTSNDNRMEVRRNWDLLMplGSGSILVPDYKeHP 170
                 4444444444444444444444444343443222222222222223333333344444566667778888888******77761145566666655333 PP

     DUF3328 105 rlgkdpaaelevedkseggyiaglevfHqLHCLnllrkalypeyygypglsegeeee..drvHleHCidiLrqsimChaDvtlitfnwvkgtkgpvpd. 200
                  lg +       +d+   g i + +  H LHCL     ++++          + + +  ++ H++HC+++Lr++i+C+ D tl++        +p ++ 
  EEA22365.1 171 LLGDPI-----TDDPIRSGPIFEASWTHALHCLYYAVDSYHQLVV-------NGPSDsdNPYHAAHCFEYLRNNILCNLDMTLEGSMS-----TPSDKe 252
                 333333.....444444589*************777777766666.......2222223578**********************6444.....333333 PP

     DUF3328 201 fntehqCrdfealldWaee 219
                  ++ h Cr+  +  +W e+
  EEA22365.1 253 RGQPHVCRNRAEAIEWIEK 271
                 47789****8888899877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (283 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       353  (0.0196888); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.23s 00:00:00.69 Elapsed: 00:00:00.39
# Mc/sec: 2192.69
//
Query:       EEA22366.1  [L=275]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.6e-52  176.3   0.0      1e-51  175.9   0.0    1.1  1  DUF3328   Domain of unknown function (DUF3328)


Domain annotation for each model (and alignments):
>> DUF3328  Domain of unknown function (DUF3328)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  175.9   0.0   5.6e-56     1e-51      14     220 .]      61     266 ..      48     266 .. 0.91

  Alignments for each domain:
  == domain 1  score: 175.9 bits;  conditional E-value: 5.6e-56
     DUF3328  14 lllvlllllllllllilssllsssekkaakkkspsspspaldaieyelkqfklgskeapsiyrgepspevdaaW.ddllkleailipreelrrlgkdp. 110
                  ++ ++lll+++ l+i+s+ + ss++  +  +++s++spa+ +++y+ ++++  +++  + + g    evd aW ++++++++ +ip+++l++lg ++ 
  EEA22366.1  61 WIIHFSLLLTSFTLFIFSTYSRSSSTLDHV-RQFSAWSPADVSVKYNDVKYN--FTKSAQRFVGYGP-EVDTAWrEISYDVGDQWIPKSGLAKLGMPEy 155
                 567889999999999999999999999998.9******************99..9999999999765.******************************9 PP

     DUF3328 111 aaelevedkseggyiaglevfHqLHCLnllrkalypeyy.gypglsegeeeedrvHleHCidiLrqsimChaDvtlitfnwvkgtkgpvpdfntehqCr 208
                 + +++++ + e+gy +g+evfHqLHCLnllrk  y+eyy   +g   +  e++++H+ HC+++Lr +i+C+aD++l+t + v+g+++++p++n +h Cr
  EEA22366.1 156 SLKVDHPVTGEEGYRVGMEVFHQLHCLNLLRKVTYKEYYePLGGEFAAGREALQHHTNHCLEVLRMNIQCTADIGLFTLYMVEGDPQAWPELNSRHVCR 254
                 999999999******************************63344444555559********************************************** PP

     DUF3328 209 dfealldWaeen 220
                 df+++++Wa en
  EEA22366.1 255 DFDQVREWALEN 266
                 *********886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       336  (0.0187406); expected 358.6 (0.02)
Passed bias filter:                      291  (0.0162307); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.24s 00:00:00.68 Elapsed: 00:00:00.41
# Mc/sec: 2019.61
//
Query:       EEA22367.1  [L=545]
Description: HMG box-containing protein R545, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.16   12.4   0.2         13    6.2   0.0    2.5  2  PEX-2N    Peroxisome biogenesis factor 1, N-terminal
        8.5    6.3  10.1         12    5.8   1.5    2.8  2  MtrG      Tetrahydromethanopterin S-methyltransferase, subuni


Domain annotation for each model (and alignments):
>> PEX-2N  Peroxisome biogenesis factor 1, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   0.0    0.0015        13      28      73 ..     271     314 ..     262     321 .. 0.68
   2 ?    3.4   0.0     0.011        96      35      59 ..     507     531 ..     499     544 .. 0.81

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0015
                 T--EEE.ESSS.--EEE-EEE-SS-------EEEEEHHHHHHTT--T CS
      PEX-2N  28 nqalel.swgdsqpvfLsWveerssssqdeneveinrqlgeklGlkd 73 
                 +qa e   w++++  f sWv++r+++++++   +i+ + + k G k+
  EEA22367.1 271 QQADEFgPWDSTTDEFGSWVDKREAHHTEA---QIAAKNAAKKGGKK 314
                 566665249***********9999988874...55444444444444 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.011
                 SSS.--EEE-EEE-SS-------EE CS
      PEX-2N  35 wgdsqpvfLsWveerssssqdenev 59 
                 w++++  f sWv++r++++++++ +
  EEA22367.1 507 WDSTTDEFGSWVDKREAHHTEAQIA 531
                 999999*********9999887655 PP

>> MtrG  Tetrahydromethanopterin S-methyltransferase, subunit G
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   1.5    0.0013        12       4      46 ..     333     376 ..     331     380 .. 0.84
   2 ?    4.1   1.8    0.0046        42      13      46 ..     448     482 ..     441     486 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0013
        MtrG   4 svvvdpddfnevkkr.LdeieekvefvnsEiaqriGkkvGRdiG 46 
                 + v ++++ + v+kr  d+ e kve  n+    + Gkk G+  G
  EEA22367.1 333 QEVDESQEVDGVDKReVDQTEAKVETKNAAKKGKKGKKGGKKAG 376
                 55667778888888768********************9998665 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.0046
        MtrG  13 nevkkr.LdeieekvefvnsEiaqriGkkvGRdiG 46 
                 + v+kr  d+ e kve  n+    + Gkk G+  G
  EEA22367.1 448 DGVDKReVDQTEAKVETKNAAKKGKKGKKGGKKAG 482
                 5566554899*****************99998665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (545 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1218  (0.0679346); expected 358.6 (0.02)
Passed bias filter:                      248  (0.0138323); expected 358.6 (0.02)
Passed Vit filter:                        73  (0.00407162); expected 17.9 (0.001)
Passed Fwd filter:                        36  (0.00200792); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 1.14u 0.38s 00:00:01.52 Elapsed: 00:00:00.55
# Mc/sec: 2977.09
//
Query:       EEA22368.1  [L=396]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (396 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       418  (0.0233142); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 2723.96
//
Query:       EEA22369.1  [L=407]
Description: endo-1,4-beta-xylanase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   5.5e-102  341.1   0.0   6.4e-102  340.9   0.0    1.0  1  Glyco_hydro_10  Glycosyl hydrolase family 10
    1.2e-13   50.8  10.0    1.2e-13   50.8  10.0    2.4  2  CBM_1           Fungal cellulose binding domain
  ------ inclusion threshold ------
      0.049   13.9   0.0      0.083   13.1   0.0    1.3  1  DUF4269         Domain of unknown function (DUF4269)
        2.3    6.2   5.2        3.2    5.7   5.2    1.1  1  Sporozoite_P67  Sporozoite P67 surface antigen


Domain annotation for each model (and alignments):
>> Glyco_hydro_10  Glycosyl hydrolase family 10
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  340.9   0.0  1.4e-105  6.4e-102       2     314 ..      21     331 ..      20     333 .. 0.96

  Alignments for each domain:
  == domain 1  score: 340.9 bits;  conditional E-value: 1.4e-105
                     HHHHHHHTT..EEEEEESCHGHHCTTHHHHHHHHH-SEEEESSTTSHHHHCSBTTBEE-HHHHHHHHHHHHTT-EEEEEEEEESSS--HHHHTSC CS
  Glyco_hydro_10   2 lkelakakf..kvgtavsaselegeskekellkkefnsltaeNemKwealepsegnftfekadklvdfakennmkvrGHtLvWhsqlPdwvkken 94 
                     l+++aka++  ++gtav++ +l++++  ++l +++f+++t+ N mKw+ +ep++g++tf+++d++++ ak+nn  +r HtL W++qlP+++++ +
      EEA22369.1  21 LDTAAKAAGllYFGTAVDNPDLSDSQYLATLQTADFGQITPANGMKWQPTEPTQGTYTFSDGDQIASLAKSNNDYLRCHTLAWYNQLPSYITSGS 115
                     67788999999*************9777888889***********************************************************87 PP

                     CCHHHHHHHHHHHHHHHHHHHHTTTTESEEEEEES-B-TTSCSBE-SHHHHHHTTHHHHHHHHHHHHH-TTSEEEEEESSTTSTSHHHHHHHHHH CS
  Glyco_hydro_10  95 gskaeeallkrlenhiktvverykgkiyawDVVNEavddnggslresvwyqilGedyiekAFeaAreadpdakLyyNDYnieeanakrkavvelv 189
                     +++++  l ++l++hik vv++ykg+ yawDVVNEa++++g ++r+ v+yq +Ge yi +AF aA +adp+akLyyNDYnie a+ak+++   +v
      EEA22369.1 116 WTNQT--LIAALQEHIKGVVTHYKGQCYAWDVVNEALNEDG-TYRQNVFYQHIGEAYIPIAFAAAAAADPNAKLYYNDYNIEYAGAKATGAQGIV 207
                     66666..*********************************7.9**************************************************** PP

                     HHHHHTT----EEEE--EEETTSC.HHHHHHHHHHHHHTTTSEEEEEEEEEECETTSSHHHHHHHHHHHHHHHHHHHHHCTTTEEEEEESSSBGG CS
  Glyco_hydro_10 190 kelkekgvpidgvGiQsHlsvdsp.siseieaalkklaalglevaitELDirvkkssseeealeaqakrykelvkallevkekitgvtvWgvtDk 283
                     k +k+ g  idgvG+QsH++v+++ s ++ +a+l +++alg++vaitELDir++ +  +++ +++q+++y+++++a++++k  + g+t+W++tDk
      EEA22369.1 208 KLVKAAGGRIDGVGFQSHFIVGQTpSLAAQKANLASFTALGVDVAITELDIRMTLPD-TSALQAQQSTDYQTTTTACVQTK-GCVGITIWDFTDK 300
                     *******************998875999999**********************8877.58999999***************.************* PP

                     GSTTHHHSTTEC--SSB-TTS-B-HHHHHHH CS
  Glyco_hydro_10 284 ysWlsglkkkeeapllfdsnyqpkpayeavv 314
                     ysW++g++++++ ++++dsny++kpay++++
      EEA22369.1 301 YSWVPGTFSGQGDACPWDSNYNKKPAYYGIL 331
                     ****************************996 PP

>> CBM_1  Fungal cellulose binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   1.5       1.3   5.8e+03      12      23 ..     279     290 ..     275     292 .. 0.75
   2 !   50.8  10.0   2.7e-17   1.2e-13       1      29 []     375     403 ..     375     403 .. 0.98

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 1.3
       CBM_1  12 GpTtCvsgatCt 23 
                   T+Cv+   C+
  EEA22369.1 279 TTTACVQTKGCV 290
                 579999876675 PP

  == domain 2  score: 50.8 bits;  conditional E-value: 2.7e-17
       CBM_1   1 lwgQCGGigWtGpTtCvsgatCtyqNeyY 29 
                 +wgQCGGigW+GpTtCvs++ C++ N+yY
  EEA22369.1 375 HWGQCGGIGWNGPTTCVSPYACQVFNPYY 403
                 5**************************** PP

>> DUF4269  Domain of unknown function (DUF4269)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   1.9e-05     0.083      11      66 ..     233     288 ..     229     304 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.9e-05
     DUF4269  11 kLkefepvlvgtipididveesDlDiicevedleafkaalekefskledfsvkekt 66 
                 +L++++  l++  ++++dv+   lDi ++++d++a++a+ ++++++++   v++k 
  EEA22369.1 233 SLAAQKANLASFTALGVDVAITELDIRMTLPDTSALQAQQSTDYQTTTTACVQTKG 288
                 58899999*************************************99998888765 PP

>> Sporozoite_P67  Sporozoite P67 surface antigen
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   5.2   0.00071       3.2     177     302 ..     200     375 ..     172     389 .. 0.53

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.00071
  Sporozoite_P67 177 qdpavsvsgvvgvpGlgvpGvGvpGvggvgvlpgvgvprvgvapgvGvgglggvpgvgv.........lesnssseGeedddeeeeeenksie.. 260
                        a ++  +v ++G  + GvG      vg +p +   ++ +a  +  g    +  + +         l+++ s++ +++               
      EEA22369.1 200 ATGAQGIVKLVKAAGGRIDGVGFQSHFIVGQTPSLAAQKANLASFTALGVDVAITELDIrmtlpdtsaLQAQQSTDYQTTTT----------Acv 284
                     4444455556788888888888888888888888888888888777776445554444422111111122222222222211..........123 PP

  Sporozoite_P67 261 .............................................pgvGvpGvrv....gaatssssttspsssttt...ttpassgpsaqgsh 302
                                                                      ++G++      +++s+  tt+ +++t+t   tt++ss+ps+  +h
      EEA22369.1 285 qtkgcvgitiwdftdkyswvpgtfsgqgdacpwdsnynkkpayygI---LAGLKSgsgsPSSSSTLITTTKPTTTSTappTTTTSSSPSTGAAH 375
                     3445555566666666666666666666666666666666543221...344444211122222223444444444334477888888876665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (407 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       674  (0.0375927); expected 358.6 (0.02)
Passed bias filter:                      428  (0.0238719); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.39
# Mc/sec: 3106.40
//
Query:       EEA22370.1  [L=962]
Description: ATP-dependent bile acid permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      2e-27   96.3   0.2    5.3e-18   65.8   0.0    2.8  2  ABC_tran      ABC transporter
    2.3e-05   24.6   0.1       0.16   12.1   0.0    2.6  2  AAA_33        AAA domain
    2.3e-05   24.9   0.1       0.11   13.0   0.0    2.4  2  AAA_18        AAA domain
    9.2e-05   22.7   0.9       0.56   10.5   0.2    2.6  2  AAA_22        AAA domain
    0.00021   21.0   4.0       0.26   11.0   0.5    2.6  2  AAA_29        P-loop containing region of AAA domain
    0.00028   21.0   1.8      0.021   14.9   0.2    2.3  2  Dynamin_N     Dynamin family
    0.00039   20.0   2.1       0.38   10.3   0.1    2.6  3  AAA_25        AAA domain
    0.00089   19.3   0.6        2.1    8.5   0.1    2.7  2  MMR_HSR1      50S ribosome-binding GTPase
     0.0015   18.4   0.2        0.1   12.4   0.0    2.4  2  AAA_21        AAA domain, putative AbiEii toxin, Type IV TA s
     0.0025   18.0   2.9       0.15   12.1   0.4    2.4  2  DUF87         Helicase HerA, central domain
     0.0031   17.3   0.7       0.59    9.8   0.1    2.3  2  AAA_24        AAA domain
     0.0041   17.1   0.6       0.48   10.3   0.0    2.5  2  NACHT         NACHT domain
     0.0066   16.4   0.3          3    7.7   0.0    2.3  2  RsgA_GTPase   RsgA GTPase
  ------ inclusion threshold ------
      0.012   15.9   0.3        5.3    7.4   0.1    2.4  2  AAA_16        AAA ATPase domain
      0.026   13.9   1.2          2    7.7   0.1    2.5  2  FtsK_SpoIIIE  FtsK/SpoIIIE family
      0.049   12.7   1.3        4.4    6.3   0.1    2.3  2  T2SSE         Type II/IV secretion system protein
      0.066   13.6   0.1         18    5.8   0.0    2.5  2  RNA_helicase  RNA helicase
      0.067   13.2   3.1          1    9.4   0.1    2.7  3  TsaE          Threonylcarbamoyl adenosine biosynthesis protei
       0.13   11.9   1.7         12    5.4   0.4    2.4  2  cobW          CobW/HypB/UreG, nucleotide-binding domain
       0.13   11.4   1.1        2.4    7.3   0.0    2.2  2  NB-ARC        NB-ARC domain
       0.31   11.5   4.8        9.7    6.6   0.7    2.4  2  AAA_23        AAA domain
       0.38   10.5   5.2        1.1    8.9   0.3    2.8  3  ATP_bind_1    Conserved hypothetical ATP binding protein
        0.4   10.2   1.4        5.2    6.5   0.1    2.2  2  AAA_7         P-loop containing dynein motor region
       0.42   10.6   1.3        8.4    6.4   0.1    2.5  2  AAA_5         AAA domain (dynein-related subfamily)
       0.61    9.7   1.7         19    4.8   0.3    2.2  2  AAA_15        AAA ATPase domain
        1.4    8.3   3.3         17    4.8   0.1    2.3  2  Pox_A32       Poxvirus A32 protein
        2.2    7.7   3.7         14    5.1   0.2    3.0  3  SMC_N         RecF/RecN/SMC N terminal domain


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.4   0.0   6.2e-09   4.1e-06      11     117 ..     433     524 ..     421     525 .. 0.90
   2 !   65.8   0.0     8e-21   5.3e-18       2     114 ..     764     891 ..     763     894 .. 0.86

  Alignments for each domain:
  == domain 1  score: 27.4 bits;  conditional E-value: 6.2e-09
                 TSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHHHHHTCHHHHHHHSTTGGTTCBGESTTSGGS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  11 gekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvrenesdeeiekalsklglkelkdtvvksspssL 109
                 g+++a++G+ G+GKSt+lk lag++    G++ +               ++++++q+p l +++ +r+n  +  ++   +++   +  +t ++s+ ++L
  EEA22370.1 433 GNLIAVIGPVGSGKSTFLKGLAGETLILRGDLFI------------KYPHLAFCEQTPWLANGT-IRDNIITCGLDLDFKRMPAGD--ETLMGSNSAKL 516
                 889***********************99999933............35899************9.****************99999..99********* PP

                 -HHHHHHH CS
                 xxxxxxxx RF
    ABC_tran 110 SgGqkqrv 117
                 SgGq+qrv
  EEA22370.1 517 SGGQRQRV 524
                 *******8 PP

  == domain 2  score: 65.8 bits;  conditional E-value: 8e-21
                 EEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH......HHHTCHHHHHHHSTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxx RF
    ABC_tran   2 knvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren......esdeeiekalsklgl 94 
                 + ++l+++ gek+++ G++G+GKStL+  l++l++  +G+il+dg+d++ +++++lr+++++l+qe++lfp++ +r+n        + ei +al+ ++l
  EEA22370.1 764 NGLHLHISIGEKIGLCGRTGSGKSTLALSLLRLTELVSGRILIDGQDVTLISKSFLRQRVSCLSQEAFLFPGT-IRQNadplnnMTNTEIINALRCVEL 861
                 67899********************************************************************.99999*9998666677777777777 PP

                 GG............TTCBGESTTSGGS-HHHH CS
                 xx............xxxxxxxxxxxxxxxxxx RF
    ABC_tran  95 ke............lkdtvvksspssLSgGqk 114
                  +            + d ++  ++s+LS+Gq 
  EEA22370.1 862 WDalvaihggneevVLDAKL--NDSNLSHGQN 891
                 77777777765544444444..45******95 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.1   0.0   0.00024      0.16       1      22 [.     435     456 ..     435     471 .. 0.85
   2 !    9.7   0.0    0.0014      0.91       4      24 ..     778     798 ..     776     857 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00024
      AAA_33   1 lvllvGlpGsGKstlaerllkk 22 
                 l+ ++G+ GsGKst++++l+ +
  EEA22370.1 435 LIAVIGPVGSGKSTFLKGLAGE 456
                 6889**************9955 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.0014
      AAA_33   4 lvGlpGsGKstlaerllkklg 24 
                 l+G  GsGKstla +ll+ + 
  EEA22370.1 778 LCGRTGSGKSTLALSLLRLTE 798
                 7**************995443 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.7   0.0    0.0017       1.2       1      21 [.     436     456 ..     436     478 .. 0.84
   2 !   13.0   0.0   0.00017      0.11       1      70 [.     776     868 ..     776     914 .. 0.73

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0017
      AAA_18   1 IlltGtpGvGKttlakeLskr 21 
                 I++ G+ G+GK+t+ k L+ +
  EEA22370.1 436 IAVIGPVGSGKSTFLKGLAGE 456
                 89**************99765 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 0.00017
      AAA_18   1 IlltGtpGvGKttlakeLskrlgf............gvnlrdvakenglllevdpe........aldeskrldedkldklldaleenss...a 70 
                 I+l+G  G+GK+tla  L +++++              ++++ ++++ ++l+++++          d+ + +      ++l+++e +++    
  EEA22370.1 776 IGLCGRTGSGKSTLALSLLRLTELvsgrilidgqdvTLISKSFLRQRVSCLSQEAFlfpgtirqNADPLNNMTNTEIINALRCVELWDAlvaI 868
                 89****************998877787788887777666677777777777777766666555555555555555556666666666555553 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.5   0.2   0.00084      0.56       6      26 ..     434     454 ..     433     461 .. 0.87
   2 !   10.0   0.0    0.0012      0.79      10      30 ..     778     798 ..     775     832 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00084
      AAA_22   6 gilvvtGesGtGKTtllrrll 26 
                 ++++v+G++G+GK+t l+ l+
  EEA22370.1 434 NLIAVIGPVGSGKSTFLKGLA 454
                 5799***********999765 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.0012
      AAA_22  10 vtGesGtGKTtllrrlleqld 30 
                 ++G +G+GK+tl+  ll+  +
  EEA22370.1 778 LCGRTGSGKSTLALSLLRLTE 798
                 8************99998765 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.5    0.0004      0.26      23      39 ..     433     450 ..     423     455 .. 0.79
   2 !   10.4   0.2   0.00063      0.42      17      38 ..     768     789 ..     762     796 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.0004
      AAA_29  23 g.atlltGpsGsGKSTll 39 
                 g  + ++Gp GsGKST+l
  EEA22370.1 433 GnLIAVIGPVGSGKSTFL 450
                 556789**********98 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00063
      AAA_29  17 ieidlkgatlltGpsGsGKSTl 38 
                 ++i+  + + l G++GsGKSTl
  EEA22370.1 768 LHISIGEKIGLCGRTGSGKSTL 789
                 56666667889**********9 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.2   3.1e-05     0.021       1      27 [.     436     462 ..     436     466 .. 0.91
   2 ?    5.3   0.1     0.028        19       1      27 [.     776     802 ..     776     816 .. 0.85

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 3.1e-05
                 EEEEEBTTTTHHHHHHHHHTS--S--- CS
   Dynamin_N   1 iavvGsqSsGKSSvlnaLlgedilprg 27 
                 iav+G + sGKS++l  L ge +  rg
  EEA22370.1 436 IAVIGPVGSGKSTFLKGLAGETLILRG 462
                 89*******************988777 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.028
                 EEEEEBTTTTHHHHHHHHHTS--S--- CS
   Dynamin_N   1 iavvGsqSsGKSSvlnaLlgedilprg 27 
                 i ++G + sGKS+++ +Ll+   l++g
  EEA22370.1 776 IGLCGRTGSGKSTLALSLLRLTELVSG 802
                 789************999987766666 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.6   0.0    0.0019       1.3      29      65 ..     429     467 ..     400     479 .. 0.74
   2 !   10.3   0.1   0.00057      0.38      29      54 ..     769     794 ..     754     804 .. 0.84
   3 ?   -2.6   0.1       5.3   3.5e+03     158     188 ..     889     918 ..     860     919 .. 0.59

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0019
      AAA_25  29 llpagelallaGapgtGKttlaldlalava..tGkpwlg 65 
                   p g l++++G+ g+GK+t++  la +++  +G+ + +
  EEA22370.1 429 SSPIGNLIAVIGPVGSGKSTFLKGLAGETLilRGDLFIK 467
                 457799*******************99988778876655 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00057
      AAA_25  29 llpagelallaGapgtGKttlaldla 54 
                 ++  ge + l+G++g+GK+tlal+l 
  EEA22370.1 769 HISIGEKIGLCGRTGSGKSTLALSLL 794
                 677789999**************996 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 5.3
      AAA_25 158 densnsdvgalvealeriarrtgaavllvhH 188
                 + n +++++a v+++ r +    ++v++v H
  EEA22370.1 889 GQNLDTETDAKVQMVIR-KSFRECTVIMVAH 918
                 44444555555555444.2345588888888 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.5   0.1    0.0031       2.1       2      23 ..     436     457 ..     435     465 .. 0.88
   2 !    8.4   0.1    0.0034       2.3       1      21 [.     775     795 ..     775     813 .. 0.85

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.0031
                 EEEEESTTSSHHHHHHHHHTST CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltgek 23 
                 +a++G   +GKSt+++ l ge+
  EEA22370.1 436 IAVIGPVGSGKSTFLKGLAGET 457
                 89***************99985 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0034
                 EEEEEESTTSSHHHHHHHHHT CS
    MMR_HSR1   1 evaivGrpNvGKStLinaltg 21 
                 ++++ Gr+ +GKStL  +l++
  EEA22370.1 775 KIGLCGRTGSGKSTLALSLLR 795
                 589************998886 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.4   0.0   0.00015       0.1       2      20 ..     436     454 ..     435     482 .. 0.87
   2 ?    3.5   0.1     0.078        52       3      22 ..     777     796 ..     776     823 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00015
      AAA_21   2 nvliGpNgsGKSnLLdald 20 
                  ++iGp gsGKS++L+ l 
  EEA22370.1 436 IAVIGPVGSGKSTFLKGLA 454
                 689*************995 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.078
      AAA_21   3 vliGpNgsGKSnLLdaldll 22 
                 +l G+ gsGKS+L   l  l
  EEA22370.1 777 GLCGRTGSGKSTLALSLLRL 796
                 689**********7777666 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.1     0.022        15      13      46 ..     424     456 ..     416     466 .. 0.75
   2 !   12.1   0.4   0.00023      0.15      22      46 ..     772     796 ..     760     807 .. 0.78

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.022
       DUF87  13 pvyldlnklvtrHlAilgsTGsGKSntvavLlee 46 
                 ++ l+  + +   +A++g  GsGKS++ + L  e
  EEA22370.1 424 TLTLKS-SPIGNLIAVIGPVGSGKSTFLKGLAGE 456
                 555555.4456679*************9988766 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 0.00023
       DUF87  22 vtrHlAilgsTGsGKSntvavLlee 46 
                 + + ++  g+TGsGKS+++ +Ll+ 
  EEA22370.1 772 IGEKIGLCGRTGSGKSTLALSLLRL 796
                 66789999**************974 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.8   0.1   0.00089      0.59       5      29 ..     436     460 ..     433     465 .. 0.89
   2 ?    5.5   0.0     0.018        12       4      22 ..     775     793 ..     772     807 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00089
      AAA_24   5 iliyGpsgiGKTtlakelgpkplfi 29 
                 i+++Gp g+GK+t++k l  ++l++
  EEA22370.1 436 IAVIGPVGSGKSTFLKGLAGETLIL 460
                 89****************9999987 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.018
      AAA_24   4 kiliyGpsgiGKTtlakel 22 
                 ki + G  g+GK+tla++l
  EEA22370.1 775 KIGLCGRTGSGKSTLALSL 793
                 899*************998 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.3   0.0   0.00073      0.48       2      23 ..     435     456 ..     434     497 .. 0.69
   2 ?    4.3   0.2     0.052        35       5      21 ..     778     794 ..     775     799 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00073
                 CEEEEC-TTTCHHHHHHHHHHH CS
       NACHT   2 lvilqGeaGsGKTtLlqklala 23 
                 l+++ G+ GsGK+t+l++la +
  EEA22370.1 435 LIAVIGPVGSGKSTFLKGLAGE 456
                 689****************954 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.052
                 EEC-TTTCHHHHHHHHH CS
       NACHT   5 lqGeaGsGKTtLlqkla 21 
                 l G+ GsGK+tL+ +l 
  EEA22370.1 778 LCGRTGSGKSTLALSLL 794
                 679*********98886 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.7   0.0    0.0045         3      92     123 ..     426     457 ..     395     465 .. 0.82
   2 ?    6.3   0.1     0.013       8.3     102     121 ..     776     795 ..     718     816 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0045
                  HHHHHCTTSEEEEECSTTSSHHHHHHHHCTT- CS
  RsgA_GTPase  92 elkellkdktsvlvGqSGvGKStLinallpel 123
                  +lk+   +++++++G+ G GKSt+++ l++e+
   EEA22370.1 426 TLKSSPIGNLIAVIGPVGSGKSTFLKGLAGET 457
                  566666778999**************999874 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.013
                  EEEECSTTSSHHHHHHHHCT CS
  RsgA_GTPase 102 svlvGqSGvGKStLinallp 121
                  + l+G +G GKStL  +ll 
   EEA22370.1 776 IGLCGRTGSGKSTLALSLLR 795
                  559***********888765 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.1     0.008       5.3      23      44 ..     430     453 ..     424     472 .. 0.83
   2 ?    6.1   0.0      0.02        13      29      86 ..     778     827 ..     769     870 .. 0.71

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.008
      AAA_16  23 rp..elvllsGesGvGKsslvrel 44 
                 +p  +l+ ++G+ G+GKs+ ++ l
  EEA22370.1 430 SPigNLIAVIGPVGSGKSTFLKGL 453
                 444599*************98755 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.02
      AAA_16  29 lsGesGvGKsslvrellralekd..ggiflrgkcdqlesaipysalaqalareellrqll 86 
                 l G  G+GKs+l+ +ll +l++   g i++ g+ + l        + + + r + +  l 
  EEA22370.1 778 LCGRTGSGKSTLALSLL-RLTELvsGRILIDGQDVTL--------ISKSFLR-QRVSCLS 827
                 67999********9999.5665533344444444444........5555533.5555555 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.1     0.003         2      32      59 ..     424     453 ..     415     456 .. 0.77
   2 ?    4.2   0.1     0.036        24      44      57 ..     778     791 ..     767     795 .. 0.84

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.003
                   EEEGGGS-...SEEEE--TTSSHHHHHHHH CS
  FtsK_SpoIIIE  32 vldlkkma..shllvaGatgsGKStalntL 59 
                   +l lk+++  + + v+G  gsGKSt+l+ L
    EEA22370.1 424 TLTLKSSPigNLIAVIGPVGSGKSTFLKGL 453
                   455667777345679************976 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.036
                   EE--TTSSHHHHHH CS
  FtsK_SpoIIIE  44 vaGatgsGKStaln 57 
                   ++G+tgsGKSt   
    EEA22370.1 778 LCGRTGSGKSTLAL 791
                   69********9755 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.1     0.018        12     130     148 ..     434     452 ..     395     458 .. 0.84
   2 ?    6.3   0.1    0.0067       4.4     126     156 ..     770     800 ..     743     808 .. 0.77

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.018
       T2SSE 130 glilvsGgTgsGKttllya 148
                  li v G+ gsGK+t+l  
  EEA22370.1 434 NLIAVIGPVGSGKSTFLKG 452
                 467899**********975 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0067
       T2SSE 126 vrerglilvsGgTgsGKttllyallkeinks 156
                 ++    i + G TgsGK+tl+ +ll   +  
  EEA22370.1 770 ISIGEKIGLCGRTGSGKSTLALSLLRLTELV 800
                 5555667789**********99998776555 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.038        25       2      21 ..     437     456 ..     436     472 .. 0.87
   2 ?    5.8   0.0     0.028        18       3      20 ..     778     795 ..     776     815 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.038
  RNA_helicase   2 wlyGpsgeGKStlakeLaka 21 
                    + Gp g GKSt+ k La +
    EEA22370.1 437 AVIGPVGSGKSTFLKGLAGE 456
                   689************99865 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.028
  RNA_helicase   3 lyGpsgeGKStlakeLak 20 
                   l+G++g GKStla +L +
    EEA22370.1 778 LCGRTGSGKSTLALSLLR 795
                   89**********988764 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   0.1    0.0016         1      19      42 ..     433     456 ..     419     467 .. 0.81
   2 ?   -2.4   0.0         7   4.6e+03      93     105 ..     732     744 ..     717     760 .. 0.66
   3 ?    3.4   0.2      0.11        71      18      42 ..     772     796 ..     753     804 .. 0.77

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0016
                 TEEEEEEESTTSSHHHHHHHHHHH CS
        TsaE  19 gdvilLeGdLGaGKTtlvrglaka 42 
                 g++i+  G++G+GK+t+ +gla +
  EEA22370.1 433 GNLIAVIGPVGSGKSTFLKGLAGE 456
                 7789****************9865 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 7
                 CEEEEETGGGGCC CS
        TsaE  93 avvlvEWpeklee 105
                 +  l EWp++ e 
  EEA22370.1 732 QESLTEWPDRGEI 744
                 45799***99543 PP

  == domain 3  score: 3.4 bits;  conditional E-value: 0.11
                 HTEEEEEEESTTSSHHHHHHHHHHH CS
        TsaE  18 lgdvilLeGdLGaGKTtlvrglaka 42 
                 +g+ i L G  G+GK+tl+ +l++ 
  EEA22370.1 772 IGEKIGLCGRTGSGKSTLALSLLRL 796
                 367799************9988875 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.4   0.4     0.018        12       3      20 ..     436     453 ..     434     460 .. 0.85
   2 ?    5.1   0.0     0.022        15       3      46 ..     776     819 ..     774     831 .. 0.73

  Alignments for each domain:
  == domain 1  score: 5.4 bits;  conditional E-value: 0.018
                 EEEEESTTCCHHHHHHHH CS
        cobW   3 tvltGflGsGKTtLlnhl 20 
                 + + G++GsGK+t+l+ l
  EEA22370.1 436 IAVIGPVGSGKSTFLKGL 453
                 5689**********9876 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.022
                 EEEEESTTCCHHHHHHHHHCT--SS-EEEEESS-SSCHCCCCCC CS
        cobW   3 tvltGflGsGKTtLlnhllenraglklavivNefgevsiDaell 46 
                 ++l+G  GsGK+tL  +ll+ ++  +  +++  +  + i +++l
  EEA22370.1 776 IGLCGRTGSGKSTLALSLLRLTELVSGRILIDGQDVTLISKSFL 819
                 5799***********99998777666666665555555555555 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.2      0.12        78      21      38 ..     434     451 ..     422     463 .. 0.80
   2 ?    7.3   0.0    0.0036       2.4      23      47 ..     776     800 ..     761     825 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.12
                 EEEEEEESTTSSHHHHHH CS
      NB-ARC  21 lvvalvGmgGvGKttlak 38 
                  ++a+ G  G+GK+t +k
  EEA22370.1 434 NLIAVIGPVGSGKSTFLK 451
                 689************987 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0036
                 EEEEESTTSSHHHHHHHHCCSHCCC CS
      NB-ARC  23 valvGmgGvGKttlakqilnksdev 47 
                 ++l G+ G+GK+tla + l+  + v
  EEA22370.1 776 IGLCGRTGSGKSTLALSLLRLTELV 800
                 899************9888765555 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   0.7     0.015       9.7      20      39 ..     434     453 ..     420     455 .. 0.85
   2 ?    6.1   0.2     0.022        14      24      35 ..     778     789 ..     768     794 .. 0.90

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.015
      AAA_23  20 gltlItGpNGaGKTTildAi 39 
                 +l +++Gp G+GK+T+l  +
  EEA22370.1 434 NLIAVIGPVGSGKSTFLKGL 453
                 78999***********9876 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.022
      AAA_23  24 ItGpNGaGKTTi 35 
                 ++G +G+GK+T+
  EEA22370.1 778 LCGRTGSGKSTL 789
                 79*********9 PP

>> ATP_bind_1  Conserved hypothetical ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.2       2.6   1.7e+03     124     146 ..     143     167 ..     135     183 .. 0.76
   2 ?    8.9   0.3    0.0017       1.1       1      16 [.     438     453 ..     438     459 .. 0.91
   3 ?    2.8   0.0      0.13        87       2      22 ..     779     799 ..     778     805 .. 0.83

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 2.6
  ATP_bind_1 124 lvvvyLvDsqrltd..ptkfisgll 146
                 l+ v LvD +++++  p+ ++s+ l
  EEA22370.1 143 LCLVILVDLEYVRSirPSFLVSAYL 167
                 89**********9986555555544 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.0017
  ATP_bind_1   1 vvGpaGsGKttfvgal 16 
                 v+Gp+GsGK+tf + l
  EEA22370.1 438 VIGPVGSGKSTFLKGL 453
                 89**********9877 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.13
  ATP_bind_1   2 vGpaGsGKttfvgalseilel 22 
                 +G  GsGK+t+  +l  ++el
  EEA22370.1 779 CGRTGSGKSTLALSLLRLTEL 799
                 799********9988877765 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.1      0.17   1.1e+02      36      53 ..     436     453 ..     425     458 .. 0.84
   2 ?    6.5   0.1    0.0079       5.2      26      55 ..     766     795 ..     763     802 .. 0.88

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.17
       AAA_7  36 vllvGptGtGKtviikdl 53 
                 + ++Gp+G+GK++ +k l
  EEA22370.1 436 IAVIGPVGSGKSTFLKGL 453
                 6789*********99875 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0079
       AAA_7  26 lelllknkkpvllvGptGtGKtviikdllk 55 
                 l+l+++ + ++ l+G tG+GK++++ +ll+
  EEA22370.1 766 LHLHISIGEKIGLCGRTGSGKSTLALSLLR 795
                 5788999999*************9998876 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.1      0.22   1.5e+02       4      20 ..     438     454 ..     436     466 .. 0.87
   2 ?    6.4   0.1     0.013       8.4       4      23 ..     778     797 ..     775     809 .. 0.88

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.22
                 EE--SSSSHHHHHHHGG CS
       AAA_5   4 LvGppGtgKselaerla 20 
                 ++Gp G+gKs++ + la
  EEA22370.1 438 VIGPVGSGKSTFLKGLA 454
                 69*********998776 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.013
                 EE--SSSSHHHHHHHGGGGB CS
       AAA_5   4 LvGppGtgKselaerlaaal 23 
                 L G +G+gKs+la +l++++
  EEA22370.1 778 LCGRTGSGKSTLALSLLRLT 797
                 89**************9998 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.3     0.028        19      21      43 ..     432     453 ..     423     455 .. 0.85
   2 ?    3.7   0.0     0.061        40      18      45 ..     769     795 ..     766     822 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.028
      AAA_15  21 lseeltvliGkNnsGKSsileal 43 
                 + + l  +iG+ +sGKS++l+ l
  EEA22370.1 432 IGN-LIAVIGPVGSGKSTFLKGL 453
                 556.99**************976 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.061
      AAA_15  18 eidlseeltvliGkNnsGKSsilealdl 45 
                 +i++ e    l+G+ +sGKS+++  l  
  EEA22370.1 769 HISIGE-KIGLCGRTGSGKSTLALSLLR 795
                 788888.999***********9887755 PP

>> Pox_A32  Poxvirus A32 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.1     0.026        17      16      34 ..     436     454 ..     427     466 .. 0.88
   2 ?    3.7   0.4     0.054        36      16      35 ..     776     795 ..     773     802 .. 0.88

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.026
     Pox_A32  16 lalvGgsGsGktvyLlsLl 34 
                 +a++G  GsGk ++L+ L 
  EEA22370.1 436 IAVIGPVGSGKSTFLKGLA 454
                 799************9985 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.054
     Pox_A32  16 lalvGgsGsGktvyLlsLlr 35 
                 + l G +GsGk +  lsLlr
  EEA22370.1 776 IGLCGRTGSGKSTLALSLLR 795
                 6799**************97 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.2     0.021        14      25      42 ..     434     451 ..     425     455 .. 0.84
   2 ?    0.1   0.0      0.68   4.5e+02      29      44 ..     778     793 ..     770     816 .. 0.88
   3 ?    1.0   0.0      0.37   2.4e+02     170     207 ..     891     928 ..     889     935 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.021
                 SEEEEEESTTSSHHHHHH CS
                 xxxxxxxxxxxxxxxxxx RF
       SMC_N  25 sftaivGpNGSGKsnlld 42 
                 ++ a++Gp GSGKs +l 
  EEA22370.1 434 NLIAVIGPVGSGKSTFLK 451
                 5679**********9986 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.68
                 EEESTTSSHHHHHHHH CS
                 xxxxxxxxxxxxxxxx RF
       SMC_N  29 ivGpNGSGKsnlldAi 44 
                 + G+ GSGKs l  ++
  EEA22370.1 778 LCGRTGSGKSTLALSL 793
                 789*******987665 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 0.37
                 TS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC-SC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 170 aLDeknvkkvaellkeksknaQfivislreemlekadk 207
                 +LD +  +kv  +++++  ++ +i++++r ++l + d+
  EEA22370.1 891 NLDTETDAKVQMVIRKSFRECTVIMVAHRIHILLDFDR 928
                 79**************************9888777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (962 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       882  (0.049194); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        85  (0.00474092); expected 17.9 (0.001)
Passed Fwd filter:                        29  (0.00161749); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              27  [number of targets reported over threshold]
# CPU time: 0.87u 0.34s 00:00:01.21 Elapsed: 00:00:00.51
# Mc/sec: 5667.74
//
Query:       EEA22371.1  [L=527]
Description: hexose transporter protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.1e-91  306.1  20.2    4.9e-91  305.8  20.2    1.0  1  Sugar_tr  Sugar (and other) transporter
    5.2e-29  101.3  18.5    7.7e-29  100.7  18.5    1.2  1  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
       0.01   14.2  11.8        0.2    9.9   3.8    3.1  2  OATP      Organic Anion Transporter Polypeptide (OATP) family
          5    7.3  10.3        0.4   10.9   1.4    3.3  3  YtpI      YtpI-like protein


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  305.8  20.2   1.1e-94   4.9e-91       5     450 ..      34     482 ..      30     484 .. 0.91

  Alignments for each domain:
  == domain 1  score: 305.8 bits;  conditional E-value: 1.1e-94
                 HHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-T CS
    Sugar_tr   5 aalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsve 103
                 a++++  +gYd  ++++  ++ +   n+ +++ +       +++gl+++++++G+++   ++ +++d++GR+ + ++++++++ g ++  +      v 
  EEA22371.1  34 AMITSATNGYDGSLMNGLEAMKS--WNESYNNPDP------STLGLLAASMSIGSMLAIPVVPYVADILGRRAGVVMGCLIMLCGVAMVSIGY---RVA 121
                 78999****************99..3444444443......457*************************************999988776666...8** PP

                 GGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-.TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHHT CS
    Sugar_tr 104 vlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsn.adgwrillglqlvpallllilllflPESPrylvek 201
                 +++vgR+++G+g+G+a+ ++P++++E+ ++++R    ++y++ + +G l++a++ lg+n+++n a+ wr+++ lq +p++ +li+++++PESPr+l++k
  EEA22371.1 122 LFVVGRIILGFGLGIAQECAPLLVAELVHPQHRAVYSTIYNSLWYVGSLIGACVALGTNRIENsAWSWRVPCLLQGIPSVCQLIFIWTVPESPRWLISK 220
                 *************************************************************************************************** PP

                 T-HHHHHHHHHHHHHC.....HHHHHHHHHHHHHHHHHHH.....HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH...HHH CS
    Sugar_tr 202 gkeeeakevlaklrge.....edadrelaeekdsleaeqeeekaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsks...llv 292
                 gk  +ak+vla +  +     e+++ e +e++++++ e++ e +sw+el+s+ ++r r +i + + +f q +G+ ++ y+ p+++e +g+++s   l++
  EEA22371.1 221 GKNAQAKKVLAYVHAQgdeddELVNVEYEEIQQTIQLEKQFEGNSWSELWSTPGNRHRSIILISIGFFSQWSGNGIVSYFLPKVLELIGITNSntvLTI 319
                 ************666652334445555555555555555555*****************************************************999* PP

                 HHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH...HHHHTTSS........CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHH CS
    Sugar_tr 293 tiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilg.ivalllvaks.....kaasivaivfialfialfalgwgpvpwvlvsElfpqsvRs 385
                 + i+ +vn+v+     f+vd+fGRR+l+l++++gm++cfv  +   a ++ +++     + a++ +ivfi+l+ + +++g+ +++  ++sE+ p ++R+
  EEA22371.1 320 NSILNAVNVVSATGICFFVDKFGRRRLFLTSCFGMIACFVATTiALARFQISADngitnQNAANTVIVFIFLYYISYNIGFSGMLVSYSSEILPYRLRA 418
                 ******************************************9744444444446899999************************************** PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGG CS
    Sugar_tr 386 kalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeiee 450
                 k+l++ +++  l+  + +++ pi+  +i+ +++++v+ + +v+ +++v+ f++etk  +leei +
  EEA22371.1 419 KGLTLMFFCVDLSLWFNQYVNPIAIAQIK-WKYYIVYCVWLVVETVVVWKFYIETKETPLEEIVK 482
                 *****************************.********************************965 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.7  18.5   1.7e-32   7.7e-29      24     347 ..      58     430 ..      24     434 .. 0.77

  Alignments for each domain:
  == domain 1  score: 100.7 bits;  conditional E-value: 1.7e-32
       MFS_1  24 aedlg.ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgagalfpagaaliadwfpkeergr 121
                 +e+++  +ps++gll++  ++g+++a++++ +++d +Grr  +++g l+++ g+++ +++  + l++v+r++ G+g g++   +  l+a+++++++r+ 
  EEA22371.1  58 NESYNnPDPSTLGLLAASMSIGSMLAIPVVPYVADILGRRAGVVMGCLIMLCGVAMVSIGYRVALFVVGRIILGFGLGIAQECAPLLVAELVHPQHRAV 156
                 3333359**********************************666666666666344444588889********************************** PP

       MFS_1 122 aigllsagfslGailgpllgg....llasslgWravfyilaivsllafvlfllllpeepperkrkspkeee............................ 188
                 +  ++++ + +G+++g+ ++     +  s+++Wr++ ++ +i s+  ++   +  ++++++r+  s+ +                              
  EEA22371.1 157 YSTIYNSLWYVGSLIGACVALgtnrIENSAWSWRVPCLLQGIPSVCQLI---FIWTVPESPRWLISKGKNAqakkvlayvhaqgdeddelvnveyeeiq 252
                 ****************9999977777778888**************977...66667777777777777768899999999988888888888777776 PP

       MFS_1 189 ......kgtgpaplvpawkallkdp......vlwillialllfffgfsglltllplylqevlgls..glllaglllallalvgailallagrlsdrlgr 273
                       k+ ++      w++l++ p       + ++ i++++ + g+ +++++lp    e  g++  +  +++++ ++l +v++++a  + +++d++gr
  EEA22371.1 253 qtiqleKQFEGN----SWSELWSTPgnrhrsII-LISIGFFSQWSGNGIVSYFLPKV-LELIGITnsN--TVLTINSILNAVNVVSATGICFFVDKFGR 343
                 665444444444....46666666633323211.355555555666666*******7.*******652..555558888888888888888999***** PP

       MFS_1 274 rrrlllallllllaalglallavt............ssavllllvlvliGf.glgfvfpsllalasdlappeeagtasglfntagsl 347
                 rr  l +++++++++++  ++ +             + a  ++++++l+ +     ++++l ++ s+ +p + +++ + l+ ++  l
  EEA22371.1 344 RRLFLTSCFGMIACFVATTIALARfqisadngitnqNAANTVIVFIFLYYIsYNIGFSGMLVSYSSEILPYRLRAKGLTLMFFCVDL 430
                 *****************9999999999999999987555555555556555555556899999999999999999888888887766 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   1.4   0.00025       1.1      36      83 ..      67     114 ..      26     118 .. 0.81
   2 ?    9.9   3.8   4.5e-05       0.2     132     320 ..     120     341 ..     115     430 .. 0.69

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.00025
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP  36 stsgliassneignillilfvsYfggrghrPrwigigallmalgslll 83 
                 st gl+a+s  ig++l+i +v Y+++   r   + +g+l+m +g  ++
  EEA22371.1  67 STLGLLAASMSIGSMLAIPVVPYVADILGRRAGVVMGCLIMLCGVAMV 114
                 789***********************9887777777777777766655 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 4.5e-05
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 132 vllfflaqlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllklyvdidseisltpkdprWvgaWWlgflilgvllllaa 230
                 v lf+++ ++lG+G    +  +   + + v++++ ++y  i+ +l+ +G  +G  ++  ++++            +++ W   W +  l+ g+  ++  
  EEA22371.1 120 VALFVVGRIILGFGLGIAQECAPLLVAELVHPQHRAVYSTIYNSLWYVGSLIGACVALGTNRI------------ENSAW--SWRVPCLLQGIPSVCQL 204
                 569**************************************************9998888874............34556..69999999999999999 PP

                 xxxxxxxxx.....xxxxxxxxxxxxxxxxxx......x....xxxxxxxxxxxxxxx...............................x......... RF
        OATP 231 iplffFPke.....lpkkkeerakkkseeesa......e....kkeekkkkeksksse...............................e......... 274
                 i+++  P++        k +++++kk  +  +      +     + e          e                                         
  EEA22371.1 205 IFIWTVPESprwliS--KGKNAQAKKVLAYVHaqgdedDelvnVEYE----------EiqqtiqlekqfegnswselwstpgnrhrsiiLisigffsqw 291
                 999999999888533..333333333333332234332023221111..........112223333333344444444444443333330333333344 PP

                 ....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 275 ....eelkslkdfpkalkrllknpifllvilssvfeillvaGfitFlpky 320
                          l ++++ +  + +n +++++++ ++++++ ++G++ F+ k+
  EEA22371.1 292 sgngIVSYFLPKVLELIGITNSNTVLTINSILNAVNVVSATGICFFVDKF 341
                 33333333344444444555677777777777777777777777777776 PP

>> YtpI  YtpI-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   1.4   8.8e-05       0.4      31      72 ..      95     136 ..      88     140 .. 0.89
   2 ?    0.5   0.1      0.15   6.9e+02      63      85 ..     280     302 ..     279     304 .. 0.84
   3 ?   -2.5   0.3       1.3     6e+03      54      66 ..     379     391 ..     347     400 .. 0.63

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 8.8e-05
        YtpI  31 sakasialGlflilfginqllllestvalvvgavflvlGlan 72 
                   +a +++G++++l g+ ++     +  +vvg ++l +Gl+ 
  EEA22371.1  95 GRRAGVVMGCLIMLCGVAMVSIGYRVALFVVGRIILGFGLGI 136
                 56899**************99999***************986 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.15
        YtpI  63 avflvlGlanlfaGiraykhyrp 85 
                 ++++ +G+++ + G    ++++p
  EEA22371.1 280 IILISIGFFSQWSGNGIVSYFLP 302
                 899**********9888888777 PP

  == domain 3  score: -2.5 bits;  conditional E-value: 1.3
        YtpI  54 estvalvvgavfl 66 
                 +++ + v+ ++fl
  EEA22371.1 379 QNAANTVIVFIFL 391
                 4444445555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (527 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       950  (0.0529868); expected 358.6 (0.02)
Passed bias filter:                      440  (0.0245412); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.64u 0.35s 00:00:00.99 Elapsed: 00:00:00.53
# Mc/sec: 2970.89
//
Query:       EEA22372.1  [L=284]
Description: enoyl-CoA hydratase/isomerase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      6e-35  120.8   0.9      2e-22   79.7   0.8    2.1  2  ECH_1     Enoyl-CoA hydratase/isomerase
    2.2e-12   47.1   0.0    4.6e-07   29.6   0.0    2.1  2  ECH_2     Enoyl-CoA hydratase/isomerase


Domain annotation for each model (and alignments):
>> ECH_1  Enoyl-CoA hydratase/isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.2   0.0   5.2e-14   4.6e-10       2      68 ..      13      80 ..      12      92 .. 0.87
   2 !   79.7   0.8   2.3e-26     2e-22      86     197 ..     118     229 ..     115     274 .. 0.82

  Alignments for each domain:
  == domain 1  score: 39.2 bits;  conditional E-value: 5.2e-14
                EETTEEEEEE--CGCTTEE-HHHHHH.HHHHHHHHHHSTTECEEEEEEBTSEEEEEB-HHHHHHHHCH CS
       ECH_1  2 ieagvaviklnrPeavNalsaelltE.liqalekleddksvravvLtGgdkaFaaGadlkemaeeeka 68
                + +g+  i++nrP+  Na++++ ++E l +a+ ++e+d++ +  +L G ++ F++G dl+e+a+ +++
  EEA22372.1 13 TDEGITTITINRPHRRNAIDHHSTAEkLYHAILDFENDETQKIGILYGAGGTFCSGSDLHEVAKISTS 80
                5789***************9876665499********************************9997643 PP

  == domain 2  score: 79.7 bits;  conditional E-value: 2.3e-26
                 HSSSEEEEEE-SEEETHHHHHHHHSSEEEEETTTEEE-GGGGGTS--CTTCHHHHHHHHHHHHHHHHHHHT-EEEHHHHHHCTSSSEEESGGGHHHHHH CS
       ECH_1  86 tvpkpviaavnGaaigGGlelalacDiviaadnasfglnelklGlipgaggtqilarkvGkskAeeilllgkkisaqealkvGlvdkvvpeeqlleeal 184
                 +v kp+i av G+a++ Glel l++D+++a +na fg    ++G+    ggt +l+ +vG  +A  ++l+g+ ++aqe l++Glv++vv + + l eal
  EEA22372.1 118 QVRKPLIGAVAGYAVADGLELSLIADLRVAEENAIFGVFCRRFGVPLIDGGTVRLQAIVGLGRALDMILTGRAVTAQEGLQMGLVNRVVGKGEALAEAL 216
                 789*****************************************99889************************************************** PP

                 HHHHHHHHSCHHH CS
       ECH_1 185 elaeklaekspaa 197
                 ++a++l+  ++  
  EEA22372.1 217 KIARQLVAFPQMC 229
                 *******433322 PP

>> ECH_2  Enoyl-CoA hydratase/isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.6   0.0   5.1e-11   4.6e-07       2      67 ..      18      83 ..      17     100 .. 0.88
   2 !   15.5   0.1     1e-06    0.0092      86     185 ..     119     217 ..     115     268 .. 0.82

  Alignments for each domain:
  == domain 1  score: 29.6 bits;  conditional E-value: 5.1e-11
                EEEEE--GGGTT-B-H.HHHHHHHHHHHHHCC-TT-SEEEEEESSSSECE--B--HHHHHHHHCS-T CS
       ECH_2  2 gvitLnrpkalNaLsl.emvralkealkewekddevklvvlkgagekafCAGgDvralyeaakegkk 67
                ++it+nrp+  Na+++ + +++l +a+ ++e+d++ k+ +l gag   fC+G D++++++  +++++
  EEA22372.1 18 TTITINRPHRRNAIDHhSTAEKLYHAILDFENDETQKIGILYGAG-GTFCSGSDLHEVAKISTSTAQ 83
                68************8626899**********************99.89**********998877654 PP

  == domain 2  score: 15.5 bits;  conditional E-value: 1e-06
                 -SS-EEEEE-BEEETHHHHHHTTSSEEEE-TT-EEE--GGGGT----TTHHHHHHCSST.THHHHHHHH---B-HHHHHHTTS--EE--GGGHHHHHHH CS
       ECH_2  86 ypkpvvalmdGivmGgGvGlsvhgsfrvvtertvfAmPEtaIGlfPDvGgsyfLsrlpg.elGlylalTGarlkgadalaaglathyvpseklealeea 183
                 ++kp++  + G+++  G+ ls+ + +rv+ e+++f +   + G+    Gg+  L+ + g   +l + lTG+ +++++ l++gl + +v +   eal+ea
  EEA22372.1 119 VRKPLIGAVAGYAVADGLELSLIADLRVAEENAIFGVFCRRFGVPLIDGGTVRLQAIVGlGRALDMILTGRAVTAQEGLQMGLVNRVVGKG--EALAEA 215
                 78*****************************************976668888888876657788889********************9876..455555 PP

                 HH CS
       ECH_2 184 La 185
                 L+
  EEA22372.1 216 LK 217
                 54 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (284 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       367  (0.0204696); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.41u 0.28s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 2064.09
//
Query:       EEA22373.1  [L=346]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.7e-32  112.8   0.0      2e-32  112.6   0.0    1.1  1  NmrA             NmrA-like family
    1.8e-08   34.5   0.0    2.8e-08   33.9   0.0    1.2  1  NAD_binding_10   NAD(P)H-binding
    0.00086   18.8   0.0     0.0013   18.2   0.0    1.4  1  Epimerase        NAD dependent epimerase/dehydratase family
  ------ inclusion threshold ------
      0.017   15.0   0.0      0.026   14.4   0.0    1.2  1  KR               KR domain
       0.16   12.2   0.0       0.24   11.7   0.0    1.3  1  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma


Domain annotation for each model (and alignments):
>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.6   0.0   5.5e-36     2e-32       1     228 [.       7     240 ..       7     290 .. 0.90

  Alignments for each domain:
  == domain 1  score: 112.6 bits;  conditional E-value: 5.5e-36
                 EEESSTTSHHHHHHHHHHHH.HT-EEEEEES-S-SHHHHHHHHSTTEEE.ES-TT-HHHHHHHHTT-SEEEE---GG....S-HHHHHHHHHHHHHHHS CS
        NmrA   1 IlviGaTGrqGksvvrallk.aghkvralvRdtkselakslkeaGvelv.kgdlddkeslvealkgvdvvfsvtgfy....skeiedgkklvdAakeaG 93 
                 IlviG+TG+qG+svv+al +   ++vr+l+R++ s+++++l++ +++++ +g+ d+++ l++a+ gv+++++++  +    ++e+ +g +  + a + G
  EEA22373.1   7 ILVIGGTGAQGSSVVNALSEsGRYSVRILTRNPASDRSRELAALPNVVLlQGSQDSQNDLHTAFTGVYGAWVNLDGFtigeKNELFYGIRAYEIARHHG 105
                 9******************94559***********************999***********************987779999***************** PP

                 -SEEEEEE---GG.GT.S.SS---TTTHHHHHHHHHHHHC...TS-EEEEEE-EEGGG-BS.SS-SS-BEEE-TTS.-EEEEESS-TTS-EE-HHHHHH CS
        NmrA  94 vkhfiySslgddndrsna.eepavphfdsKaeieeyvral...gipytfvyagffmenfls.llaqlkvgdtappedkvtllgpgnpkavlldaeeDiG 187
                 vkh++++++  + ++    e+ +  h d+K ++ + + +    ++ ++ + +g +m  +   ++++    +++ ++ ++++  p+     +l+a +D+G
  EEA22373.1 106 VKHYVFANIDYALRKAGWsEQYHCGHTDAKGRVGDLILSHgqsTMTTSLLTTGPYMDMLYDgMFVP----EEQADG-SFVWENPAADGKIPLIALDDVG 199
                 ********9988877764145688999**********998777899999*******9876515555....666665.8******995555559****** PP

                 HHHHHHHHHHHHHTTEEEEE-SEEE-HHHHHHHHHHHHTS- CS
        NmrA 188 afvikilkdprklkgkriklagntlsgneivelfekkigkt 228
                  + + i+++p++  g+ +++a++ +s+ eive f++++gk+
  EEA22373.1 200 VYSLWIFDNPSESTGLDLEIATDQVSFAEIVETFTRVTGKK 240
                 ***************************************98 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.9   0.0   7.7e-12   2.8e-08       1      96 [.      11     112 ..      11     132 .. 0.85

  Alignments for each domain:
  == domain 1  score: 33.9 bits;  conditional E-value: 7.7e-12
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTH..HHCHHHHCTTTCEEEE--TT-CCHHHHHHTT-SEEEES-....--TCCHHHH..HHHHHHHHHH CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnp..eklaeleaeeglevvegdvtdvedlaealkgadaVvsal....ggggkdeeg..aknivdaake 87 
                     G+tG  G+ +v+ l ++g ++v++l+Rnp  ++  el+a +++ +++g+  +++dl  a++g+   +++l     g+  ++e    +++ + a+ 
      EEA22373.1  11 GGTGAQGSSVVNALSESGRYSVRILTRNPasDRSRELAALPNVVLLQGSQDSQNDLHTAFTGVYGAWVNLdgftIGE--KNELfyGIRAYEIARH 103
                     9***************************833466789999************************9999995442222..2233579999****** PP

                     CT--EEEEE CS
  NAD_binding_10  88 agvkRfvlv 96 
                     +gvk++v+ 
      EEA22373.1 104 HGVKHYVFA 112
                     ******975 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0   3.6e-07    0.0013       1      59 [.       7      69 ..       7     113 .. 0.83

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 3.6e-07
                EEEETTTSHHHHHHHHHHHHCT.SEEEEEES-STTTTCHHCHHC...EEEE--TT-HHHHHHH CS
   Epimerase  1 ilVtGatGfiGsalvkallekg.yevigldrlssasntarledl...elveldltdrsalerl 59
                ilV+G+tG  Gs +v+al e g y v  l+r++ ++++ +l+ l    l ++    +++l+ +
  EEA22373.1  7 ILVIGGTGAQGSSVVNALSESGrYSVRILTRNPASDRSRELAALpnvVLLQGSQDSQNDLHTA 69
                8*********************999*******9999988888777665555555555555555 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0   7.2e-06     0.026       3      46 ..       7      48 ..       6      75 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 7.2e-06
                EEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHH CS
          KR  3 ylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskalia 46
                 l++GG+G+ G ++++ l e+g+ ++ +l+R++ a+++s+ ++a
  EEA22373.1  7 ILVIGGTGAQGSSVVNALSESGRYSVRILTRNP-ASDRSR-ELA 48
                59******************************4.333333.344 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   6.6e-05      0.24       1      76 [.       7      80 ..       7     130 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 6.6e-05
                     EEEE--.SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHHHTTS.SEEEE- CS
  Sacchrp_dh_NADP  1 vliiGa.GsvGqavaellarhfdvdaeitvadrskeklealaakalgvrfeaialdaenyeavLaallkeg.dlvvnl 76
                     +l+iG+ G+ G++v+  l++++ +   + + +r+ ++ ++  + a+ +++   +   + + + L  + ++  ++ vnl
       EEA22373.1  7 ILVIGGtGAQGSSVVNALSESGRY--SVRILTRNPAS-DRSRELAALPNVVLLQGSQDSQND-LHTAFTGVyGAWVNL 80
                     89**********************..89999999988.555555566666666666666666.555555544666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (346 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       311  (0.0173462); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 2302.48
//
Query:       EEA22374.1  [L=353]
Description: quinone oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.4e-10   40.3   0.2    1.1e-09   38.2   0.1    2.1  2  ADH_N       Alcohol dehydrogenase GroES-like domain
    1.2e-08   35.0   0.0    5.5e-08   32.9   0.0    2.0  2  ADH_zinc_N  Zinc-binding dehydrogenase


Domain annotation for each model (and alignments):
>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.2   0.1   1.2e-13   1.1e-09       2      69 ..      14      83 ..      13      96 .. 0.85
   2 ?   -1.9   0.0      0.34   3.1e+03      12      24 ..     288     300 ..     282     346 .. 0.57

  Alignments for each domain:
  == domain 1  score: 38.2 bits;  conditional E-value: 1.2e-13
                TEEEEEEEEEEE-HHHHHHHTTS..TTTTSSSSEE---EEEEEEEEESTT-CS--TT-EEEE-SEEE-SS CS
       ADH_N  2 gevlikvkaagiCgsDlhilkgg..kelevklplilGHEivGeveevgpevkklkvGdrVvvepliscge 69
                +e+++k  a +i+  D  i +      + vklp+ilG +i+Gev+evg++v+++k+GdrVv +++  +++
  EEA22374.1 14 NEIVVKNVAIAINAYDSIIQTAAnlVVSWVKLPFILGTDIAGEVVEVGKGVTRFKIGDRVVGYAIALDKR 83
                7999************98888765566779*******************************998876655 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.34
                 EE-HHHHHHHTTS CS
       ADH_N  12 giCgsDlhilkgg 24 
                  i+gsDl + + g
  EEA22374.1 288 MINGSDLVVNEVG 300
                 5666666554443 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.9   0.0   6.1e-12   5.5e-08       5      62 ..     163     219 ..     160     270 .. 0.72
   2 ?   -1.2   0.0       0.2   1.8e+03      53      84 ..     288     316 ..     272     320 .. 0.69

  Alignments for each domain:
  == domain 1  score: 32.9 bits;  conditional E-value: 6.1e-12
                 HHHHHHHHTT-EEEEEESSHHHHHHHHHTTESEEEETTTC.HHHHHHHHHTTTSSEEEE CS
  ADH_zinc_N   5 aavqlAkalGaeviavdsseeklelakklGadevinykea.dlverikeltggegvdvv 62 
                  ++qlA+a+G+evia++s + + ++++klGa ev++y++  + v +i++++++    + 
  EEA22374.1 163 NGIQLARAAGCEVIATASPK-NHDYLQKLGAAEVLDYNTSpTAVRDIQAAFKD-RTTAG 219
                 579************87655.46**************7767777777777733.33333 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.2
                 HTTTSSEEEEEESSCSHHHHHHHHHCEEEEEE CS
  ADH_zinc_N  53 ltggegvdvvfecvGsgatleaalkllkpgGr 84 
                 +   +g d+v++ vG +a++e+ l  + ++G 
  EEA22374.1 288 MI--NGSDLVVNEVG-KAVYEDFLPQAFEQGS 316
                 33..68899999999.8888877766666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (353 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       302  (0.0168442); expected 358.6 (0.02)
Passed bias filter:                      274  (0.0152825); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 2411.03
//
Query:       EEA22375.1  [L=891]
Description: hypothetical protein PMAA_061530 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.9e-30  104.0   0.0      2e-29  101.3   0.0    2.3  2  HTH_51           Helix-turn-helix domain
    6.6e-20   71.4   0.0    2.3e-19   69.6   0.0    1.8  2  NAD_binding_4    Male sterility protein
    1.9e-08   34.5   0.0    4.4e-08   33.4   0.0    1.6  1  PP-binding       Phosphopantetheine attachment site
    1.6e-05   24.5   0.0    2.9e-05   23.7   0.0    1.3  1  Epimerase        NAD dependent epimerase/dehydratase family
     0.0027   16.9   0.0       0.21   10.7   0.0    2.3  2  Polysacc_synt_2  Polysaccharide biosynthesis protein


Domain annotation for each model (and alignments):
>> HTH_51  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0      0.35   1.3e+03      33      63 ..      32      62 ..      27      67 .. 0.85
   2 !  101.3   0.0   5.6e-33     2e-29       1      90 []     226     315 ..     226     315 .. 0.99

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.35
      HTH_51 33 valvveAFekLgcdlrsakpGqklprikhlp 63
                + ++  A + Lg  l+++ p  klp+ +  p
  EEA22375.1 32 IHYIRVARQGLGKLLSRLTPSSKLPHPSPQP 62
                789999999***************9986555 PP

  == domain 2  score: 101.3 bits;  conditional E-value: 5.6e-33
      HTH_51   1 FeeikkltdqfieetglagylkevlpkqteLvvalvveAFekLgcdlrsakpGqklprikhlpkhkrlvdylYevLeearlvdldgdeiv 90 
                 F+e+ +ltdqfie++++ +y+++ lp+ t+L+v  +++ Fe+Lgc+lr+a+ Gq l+rik+lpkh+++v+++Y vLe+a+ vdldg++++
  EEA22375.1 226 FRETTQLTDQFIEQNNFGNYVQHTLPRLTKLCVIQIIDGFEELGCSLRDAHLGQILNRIKYLPKHEQFVTFFYGVLEKAGPVDLDGSRMT 315
                 9*************************************************************************************9986 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0      0.32   1.2e+03      70      95 ..     133     158 ..      97     165 .. 0.89
   2 !   69.6   0.0   6.5e-23   2.3e-19       1     255 [.     512     762 ..     512     764 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.32
                    TSGGGG--HHHHHHHHHH--EEEE-- CS
  NAD_binding_4  70 seprlGLseedlqelaeevdviihsa 95 
                       +lG+++    ela+e+++++ sa
     EEA22375.1 133 DLANLGIDSLMGMELAREIEIMFKSA 158
                    5679******************9987 PP

  == domain 2  score: 69.6 bits;  conditional E-value: 6.5e-23
                    EE-TTSHHHHHHHHHHHHHS-.T.EEEEEE-SSSHHHHHHHHHHHT-SS-HHHHHHHHHTTTEEEEE--TTSGGGG--HHHHHHHHHH--EEEE-- CS
  NAD_binding_4   1 lTGaTGFLGkvLlekLLrttpev.kiyllvRaksgesaeeRleeelekkelfsallkelaerikvveGDlseprlGLseedlqelaeevdviihsa 95 
                    +T aTG LG++L++   +   +v + +++ R + + + + R +++le+k+lf +     + +i+v+e+D+ +p + Ls+ ++ +l+++v++iih+a
     EEA22375.1 512 VTSATGSLGSHLVAYFTKLP-NVkRMICVNRYSPSLDCRIRQRKALESKGLFLNSV--ELAKIHVLETDTVKPMMALSNLEYTKLINSVTHIIHNA 604
                    688***********999886.577****************************9997..89************************************ PP

                    SS-S.STTSSEEHHHHHHHHHHHHHHHT...........SSS--.-EEEEEE.GGGTTS-TTT--SSS-H......HHH--EEEETTTCCCHHHHH CS
  NAD_binding_4  96 AtvnfdepykellrvNveGtrevlelak...........klkklkvllhvST.ayvngeregeveekvyeegekeekldederaklkglpntYeqs 179
                      ++++++++++ +   +++r+++ela+           ++ +   + ++S+ a+v ++               + ++ ed +  +  +p++Y   
     EEA22375.1 605 WPMSITRSIHTFEQ-QFKAMRNLIELARqiscryhhfhrNGPR-VGFQFISSiATVGCYPLFSG----------KARVPEDRMLVDSVMPTGYGEA 688
                    *********98766.679**********665555544433333.58999999999999999665..........4458999999999********* PP

                    HHHHHHHHHHHHHHH---E....EEEEE-EEE--SSST---TTSHHHHHHHHHHHH-EEES-SB---TT--EEEHHHHHH CS
  NAD_binding_4 180 KalaEklvrearrrsglpv....vivRpsiitgesktGwingsdlgirgllgliakgvlpeilgdkeavldlvpvDyvan 255
                    K + E ++ e+   +++p     +ivR++ i g+  +G+ n  + ++ +++++   ++lp    d e+ l ++pv++va 
     EEA22375.1 689 KLIWETMLDETL--HKYPQhfrpMIVRIGQIAGSEGSGYWNPVEHLAFLIKSSQTLNILP----DLEGDLSWCPVNVVAA 762
                    *********999..566643444*******************994444444444455555....555559*******996 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.4   0.0   1.2e-11   4.4e-08       2      46 ..     112     156 ..     111     168 .. 0.91

  Alignments for each domain:
  == domain 1  score: 33.4 bits;  conditional E-value: 1.2e-11
  PP-binding   2 klrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefg 46 
                 k+r+l++++ g++++ i+p++dl +lG+DSl+ +el++++e  f+
  EEA22375.1 112 KVRDLICTLSGLEPDMIKPEADLANLGIDSLMGMELAREIEIMFK 156
                 69**************************************96664 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.7   0.0     8e-09   2.9e-05       1     176 [.     510     721 ..     510     741 .. 0.77

  Alignments for each domain:
  == domain 1  score: 23.7 bits;  conditional E-value: 8e-09
                 EEEETTTSHHHHHHHHHHHHCT.SE.EEEEES-STTTTCHHCHHC............EEEE--TT-HHHHHHHHHHHT-SEEEE-..-S...---HHHH CS
   Epimerase   1 ilVtGatGfiGsalvkallekg.ye.vigldrlssasntarledl............elveldltdrsalerlfkeeqpdavihl..Aa...vggvaas 80 
                 ilVt atG +Gs+lv ++ +   ++ +i+++r+s +     ++++            el ++ +++ + ++ +++  + ++  ++          ++ s
  EEA22375.1 510 ILVTSATGSLGSHLVAYFTKLPnVKrMICVNRYSPSLDCRIRQRKaleskglflnsvELAKIHVLETDTVKPMMALSNLEYTKLInsVThiiHNAWPMS 608
                 89*******************99555*******88777766666689**********777777777776666655554444433300222012356779 PP

                 HHSHHHHHHHHTHHHHHHHHHHH..........HHTCT.EEEEEEEGGGGT......SCSSSSBSTCSTTS----SSHHHHHHHHHHHHHHHHHHHH.. CS
   Epimerase  81 sedpadfieknlqgtlnlleaar..........kagvk.rllflsSsevYG......kdaeqpkeettltgplkpnspYaaaKlageklveayaaqy.. 160
                 +++   ++e+ ++ ++nl+e ar          ++g++  + f+sS ++ G       +a++p++ ++ ++     + Y+ aKl  e ++ +  ++y  
  EEA22375.1 609 ITRSIHTFEQQFKAMRNLIELARqiscryhhfhRNGPRvGFQFISSIATVGcyplfsGKARVPEDRMLVDS--VMPTGYGEAKLIWETMLDETLHKYpq 705
                 9**********************999999988877777889999998888766676433335767777444..34689***************999986 PP

                 T-EEEEEEESEEESTT CS
   Epimerase 161 glnaiilrlfnlyGpr 176
                  ++ +i+r+  + G  
  EEA22375.1 706 HFRPMIVRIGQIAGSE 721
                 6999999999998876 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.7   0.0   5.7e-05      0.21       1      42 [.     510     553 ..     510     600 .. 0.77
   2 !    3.8   0.0    0.0073        26     138     177 ..     685     723 ..     678     725 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 5.7e-05
                      EEEETTTSHHHHHHHHHHHHH.B-SEEEEEES-HHHHH.HHHHH CS
  Polysacc_synt_2   1 vlvtGagGsiGselvrqilkk.kpkkiillerdElkly.eieke 42 
                      +lvt a+Gs+Gs+lv  ++k  ++k++i ++r   +l+ +i+++
       EEA22375.1 510 ILVTSATGSLGSHLVAYFTKLpNVKRMICVNRYSPSLDcRIRQR 553
                      89******************999****99999887775245444 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.0073
                      HHHHHHHHHHHHHHGGG--SSS--EEEEEEE-EETTGTTS CS
  Polysacc_synt_2 138 mGatKrlaekllqalakeseekktkfvvvRfGNVlgSrGS 177
                      +G +K++ e +l ++ ++   ++ + ++vR G + gS+GS
       EEA22375.1 685 YGEAKLIWETMLDETLHKY-PQHFRPMIVRIGQIAGSEGS 723
                      8999*****9998887776.789999*************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (891 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       320  (0.0178482); expected 358.6 (0.02)
Passed bias filter:                      306  (0.0170673); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.68u 0.26s 00:00:00.94 Elapsed: 00:00:00.45
# Mc/sec: 5988.02
//
Query:       EEA22376.1  [L=534]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.8e-08   33.7  12.5    5.4e-08   32.8  12.5    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
    2.4e-06   26.8   0.0    4.9e-06   25.8   0.0    1.5  1  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.8  12.5     6e-12   5.4e-08       1      38 [.       7      43 ..       7      45 .. 0.94

  Alignments for each domain:
  == domain 1  score: 32.8 bits;  conditional E-value: 6e-12
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfysessk 38
                h+C  Cr+ K++Cd+  P+C+ C++++++C+ y++++ 
  EEA22376.1  7 HSCFLCRRNKRRCDKSLPSCQLCIRKGWKCS-YPQRRG 43
                89*****************************.999876 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   0.0   5.5e-10   4.9e-06      88     168 ..     211     291 ..     139     336 .. 0.72

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 5.5e-10
  Fungal_trans  88 ssslwilqsLlllelyektssdralherhhgvavrlarslgLhr.npsyvgkkslwklweeeaesrrRlwwaaFylDktial 168
                    + +++lq+  l++++e++    +++++++g   r  + +gL + n+ + g ++++  ++ e+e+rrR ww++ +lD+++ l
    EEA22376.1 211 LC-IQVLQAGILIAIFEICDAIYPAAYLTVGACARYGVVMGLDKiNQDRMGGDHNYAASWMEIEERRRAWWGVLILDRYLNL 291
                   45.99******************************9999**997355566666677777777****************9765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (534 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       584  (0.0325729); expected 358.6 (0.02)
Passed bias filter:                      485  (0.0270511); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 3589.37
//
Query:       EEA22377.1  [L=534]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.5e-20   72.3  20.9    5.1e-20   71.7  20.9    1.3  1  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.7  20.9   2.8e-24   5.1e-20       4     352 ..      79     454 ..      70     455 .. 0.84

  Alignments for each domain:
  == domain 1  score: 71.7 bits;  conditional E-value: 2.8e-24
       MFS_1   4 aaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlgaga 101
                 +++   l+r++l+ al+     dl+++   ++  +t+  + ++ a +p+  ++ r+G r vl +++++++  +++ +f  ++   ++v r+l G+++g+
  EEA22377.1  79 MFLGLQLDRGNLSNALTDNFLVDLNLTTNDYNNGTTIQLICFLTAEFPVQLIIKRYGFRIVLPTMMIVWSMVSWAQAF-MTSRaSFYVTRALIGAFEGG 176
                 455556778888888888555899************************************************666667.445557************99 PP

       MFS_1 102 lfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg......Wravfyilaivsllafvlfllllpeepperkrkspkeee...... 188
                 ++p+ + +++  ++  e +  ++++ ++ +++ ++  ll++ +++  g      W ++f+i ++++l  +++ ll+lp++p+  k     + +      
  EEA22377.1 177 FIPGTILFATYFYKAHELSVRLAFFWSTLNIARVISSLLAAGILQMRGvhgrtgWFYLFLIEGLLTLGIGIISLLYLPQSPTHTKSILYPKSWyterqe 275
                 999999999999999****************************99999999999*****************9888888888888777777777999999 PP

       MFS_1 189 .................kgtgpaplvpawkallkdpvlw.illialllfffgfsg.lltllplylqevlglsglllaglllallalvgailallagrls 268
                                  k  +pa l++  +  l+d+ +w +++i+l+    + +g +  +l l +  + g+s  + + +l+  +a++ +il+ll+++ s
  EEA22377.1 276 viminrllrddpskgltKISEPATLKD-VRNALSDRSMWgLYFIGLIAY--IPQGpVQGYLSL-TLRRIGFS-TFDSNMLSIPSAVLQIILMLLLAKSS 369
                 99**99999999999998899999999.********8986566655555..677767777777.7*******.577775666666666666******** PP

       MFS_1 269 drlgrrrrlllallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdla.ppeeagtasglfntagslggalg 352
                  r+  r++  +++ + +l +l+ +l+ +++   ++ + + ++  g+  + p+++a++s+++   ++++  ++++n++ ++g++++
  EEA22377.1 370 ERFDERTFHCFIGEFWSLPLLAALLALPAHGHNWGRFTITTMISGYPYFHPIVAAWISENTfDVKKRAITTAAYNVIVQIGSVIS 454
                 **998666666666666666666666666666666655555555****************9889******************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (534 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       805  (0.0448993); expected 358.6 (0.02)
Passed bias filter:                      480  (0.0267723); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.31s 00:00:00.90 Elapsed: 00:00:00.49
# Mc/sec: 3253.90
//
Query:       EEA22378.1  [L=355]
Description: TfdA family taurine dioxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.8e-50  171.2   0.0    4.7e-50  170.9   0.0    1.1  1  TauD      Taurine catabolism dioxygenase TauD, TfdA family


Domain annotation for each model (and alignments):
>> TauD  Taurine catabolism dioxygenase TauD, TfdA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  170.9   0.0   2.6e-54   4.7e-50       2     262 ..      38     326 ..      37     332 .. 0.84

  Alignments for each domain:
  == domain 1  score: 170.9 bits;  conditional E-value: 2.6e-54
        TauD   2 vkpltpkfgae..gvdlsdleslddel..keelrellaeygvvvfrgfplspeqqlefarrfGplygtpgrgtntkygevld.............vssv 83 
                 +++ltp +g+e  g++++++ +++d++   + +  ++ e+gvv++r ++++  q ++f++r+  l g p++ + + ++ +                +++
  EEA22378.1  38 YRDLTPVIGREytGLQIAQVLDSEDRDrlIKDIATIVSERGVVFLRSQDVTHLQMKDFCERLSTLAGCPQSSSLHIHPLTEEgselgdqislissEKQK 136
                 799****************977775544578888999*************************8666666555555555555544444466676543334 PP

        TauD  84 yesadianlayttll....wHtDlsylesppgiqlLhcleapatGGetpfvDgraaynaLpeelpellegltavrvyyhyrg........gglrteqel 170
                 + ++  ++l++t+++    wH D +++  p+++ +L  ++ p+tGG+t++++g+++y++L++++ ++leglta+++ +   +         +++ + ++
  EEA22378.1 137 KGGGLTHQLSDTSRFasvgWHADITFENVPSDYAILKIHTLPETGGDTLWASGYEVYDRLSPSMAQFLEGLTATHDATFFHDearrlgnpLREGIRGSP 235
                 4444444455555559999********************************************************988777778****77666777777 PP

        TauD 171 pavdkhprtghpvvrthpvltgrkallvnppfatrieglgtpeskelldaleelledp.eftyrfqwqeGdlvifdNrrvlHgrt.afdegeeR 262
                  +     +t hpv+rt+pv tg+k+++vn+ f++ri+g++++es+ ll++l+ l++++ + ++r +w ++d++i+dNr+ +H++t ++de   R
  EEA22378.1 236 LNSGPSLTTVHPVIRTNPV-TGWKSVFVNKGFTKRINGVTKDESDILLQYLFNLVTQNhDAQVRYKWNKNDVAIWDNRSNWHCATyDYDE--TR 326
                 777777789*********8.*************************************88*****************************54..34 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (355 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       356  (0.0198561); expected 358.6 (0.02)
Passed bias filter:                      329  (0.0183502); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.42
# Mc/sec: 2521.21
//
Query:       EEA22379.1  [L=232]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-06   27.4   0.1    4.4e-06   26.3   0.1    1.6  1  HTH_psq   helix-turn-helix, Psq domain
     0.0025   17.9   0.1      0.013   15.6   0.0    2.3  2  HTH_28    Helix-turn-helix domain
  ------ inclusion threshold ------
      0.035   13.9   0.3      0.087   12.7   0.3    1.7  1  HTH_23    Homeodomain-like domain
       0.11   12.6   0.0        0.2   11.7   0.0    1.5  1  HTH_7     Helix-turn-helix domain of resolvase


Domain annotation for each model (and alignments):
>> HTH_psq  helix-turn-helix, Psq domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.3   0.1   9.7e-10   4.4e-06       3      39 ..      17      54 ..      15      59 .. 0.84

  Alignments for each domain:
  == domain 1  score: 26.3 bits;  conditional E-value: 9.7e-10
     HTH_psq  3 ealaaAleavvnGk.mSirkAArkYgiPrsTLwrrkrg 39
                 ++ +A+ +   Gk  S+rkAA +Y++ rsTL++r++g
  EEA22379.1 17 GRILLAISDLKDGKiRSVRKAAEIYNVTRSTLQNRVNG 54
                5667778888889988*****************88887 PP

>> HTH_28  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   2.8e-06     0.013       5      33 ..      22      52 ..      20      68 .. 0.89
   2 ?   -2.0   0.0      0.88     4e+03      14      24 ..     136     146 ..     129     152 .. 0.64

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 2.8e-06
      HTH_28  5 iikllaaGh..svreaArelgisrrtvyrWi 33
                +i  l++G+  svr aA++++++r+t++  +
  EEA22379.1 22 AISDLKDGKirSVRKAAEIYNVTRSTLQNRV 52
                78889999778****************8766 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.88
      HTH_28  14 svreaArelgi 24 
                 +vr+a  ++gi
  EEA22379.1 136 RVRDAISKYGI 146
                 66666666666 PP

>> HTH_23  Homeodomain-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.3   1.9e-05     0.087      16      37 ..      28      51 ..      12      67 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 1.9e-05
      HTH_23 16 e..GlsvreIAreLgvsrrTvyrw 37
                +    svr++A++++v+r+T+++ 
  EEA22379.1 28 DgkIRSVRKAAEIYNVTRSTLQNR 51
                366569***************975 PP

>> HTH_7  Helix-turn-helix domain of resolvase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   4.5e-05       0.2      21      38 ..      30      48 ..       2      49 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 4.5e-05
                T.--STTTSSSS---SSSS CS
       HTH_7 21 G.isiskIAkevnisRsTv 38
                +  s++k A+++n++RsT+
  EEA22379.1 30 KiRSVRKAAEIYNVTRSTL 48
                466899************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (232 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       457  (0.0254894); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.43u 0.25s 00:00:00.68 Elapsed: 00:00:00.40
# Mc/sec: 1721.61
//
Query:       EEA22380.1  [L=351]
Description: voltage-gated K+ channel beta subunit (KCNAB), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.6e-67  226.0   0.0    6.3e-67  225.8   0.0    1.0  1  Aldo_ket_red  Aldo/keto reductase family


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  225.8   0.0   3.5e-71   6.3e-67       2     293 ..      25     339 ..      24     340 .. 0.94

  Alignments for each domain:
  == domain 1  score: 225.8 bits;  conditional E-value: 3.5e-71
                   EEEE-SSS-ST.TS-HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH-TTTGGG-EEEEEE.....--SSSTTSSSS-HHHHHHHHHHH CS
  Aldo_ket_red   2 lglGtwqlgskeeiskeealellrraleaGinffDtAevYgkgqseellGealkksrkkreeviiatKv.....dlrdaeiksglskenireslees 93 
                   +glG+w  +++  + kee  + +++a+e+G+nffDtAe+Y +g+se+ +Gea++  ++kr +++i+tK+     ++ +  ++ gls+++i+e  ++s
    EEA22380.1  25 IGLGGWVTFGG-HVGKEETMRCMKQAYECGVNFFDTAESYANGESEIAMGEAIQTLGWKRSDFVISTKLnwgmaNGEILINNHGLSRKHIIEGTRAS 120
                   9*****99986.*********************************************************9988877888899*************** PP

                   HHHHT-S-EEEEEE-S--TTS-.HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHH....HHTTT--EEEEE-B-BTT-HHHHTTHHHHHHHT.T-E CS
  Aldo_ket_red  94 lkrLgtdyvDllllHrpdpslpsieevldaleelvkeGkiraiGvSnfsveqleka....kkkkkvkivavqveynllreleeegllelckkk.gvp 185
                   l rL+++yvD+++ Hrpd+ +p +ee+++a++++++ G++ ++G+S++s++ +++a    k+ + + +++ q  ynll++ + eg ++ ++   g++
    EEA22380.1 121 LNRLQLEYVDIIYAHRPDRLTP-MEETVRAFHYVIERGWAFYWGTSEWSADEIQEAcgiaKSLGLIAPIVEQPLYNLLDRKKVEGEFQRLYSRcGLG 216
                   **********************.*******************************************************6666666666555544*** PP

                   EEEBSTTGGGTTGTTTSS---SSSCCC-------.............TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTSTT-SEEEE--SSHHH CS
  Aldo_ket_red 186 liaysplggGlltgkyqseedkedkeprkdlkrd.............ertsknldaaeelselakehgvslaqlalryalsqpavgivipgasnieq 269
                   l ++spl++Gll+gky+s++  ++ ++r    +d             e++  + +++ +l++l    g +l+qlal+++l++++v++vi gas++eq
    EEA22380.1 217 LTTFSPLKMGLLSGKYNSYPTAPPPGSRFADSNDkyvksvreqsygnEEWISTIQKVTKLQDLSDRLGFKLSQLALAWCLKNQNVSSVITGASRPEQ 313
                   *********************99998887665668************99999********************************************* PP

                   HHHHHGGGG-..---HHHHHHHHHHH CS
  Aldo_ket_red 270 lednldalel..klseeevaeldell 293
                   + dn+++l+l  kl+++ ++++d++l
    EEA22380.1 314 IVDNVASLKLlpKLTPDIMEQIDAIL 339
                   ********7779***********986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (351 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       379  (0.0211389); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.47
# Mc/sec: 2254.30
//
Query:       EEA22381.1  [L=644]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      1e-07   31.9   7.5    1.8e-07   31.2   7.5    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
    4.6e-06   25.9   0.3    9.1e-06   24.9   0.3    1.4  1  Fungal_trans  Fungal specific transcription factor domain
  ------ inclusion threshold ------
        0.1   11.1   0.1       0.64    8.5   0.0    1.9  2  MmgE_PrpD     MmgE/PrpD family


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.2   7.5     3e-11   1.8e-07       1      35 [.      15      47 ..      15      52 .. 0.91

  Alignments for each domain:
  == domain 1  score: 31.2 bits;  conditional E-value: 3e-11
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCT CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfyse 35
                +aCd C  +KvKCd+++P C +C+     Ctf s+
  EEA22381.1 15 RACDGCQIRKVKCDGGQP-CLSCANTKIACTF-SR 47
                69****************.************5.44 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.9   0.3   1.5e-09   9.1e-06      10     179 ..     114     287 ..     109     317 .. 0.71

  Alignments for each domain:
  == domain 1  score: 24.9 bits;  conditional E-value: 1.5e-09
  Fungal_trans  10 pqfpilhk......psflpkt....ssenssksayaspllllailalGalfsesetkesnssltses..qefiafplraeilihedfsspssslwil 94 
                   pq++i+h       p ++++t     ++++ +s  + ++ +lai + Ga+ ++ +  ++  + +     +++++++ +  +li   ++  ++ l+++
    EEA22381.1 114 PQLYIYHLklfpvwPVVNVDTviaeLQQGDQDSHDTLEAYALAISIAGATVAQLRLDRKAGENRCILraSDMAYECEKVCSLI--RYKNRVN-LNTI 207
                   66666666555555555555566333444444444444444777777777777777666444444446656666666666666..8888888.9999 PP

  Fungal_trans  95 qsLlllelyektssd.ralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrpplldds 179
                      ++l +y  + +       +h+   +++a+ ++Lh++ sy g     +++ee +  rr + w  F++++ ++l +  p++++ +
    EEA22381.1 208 RISFFLHIYYENQEPgCGESLLHLRDSISVAQLMSLHQETSYTG-----RVTEE-QNLRRLILWLLFVTERGVCLLHKLPVIIKTN 287
                   9777777777776643777777**********************.....47777.**************************86644 PP

>> MmgE_PrpD  MmgE/PrpD family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0     0.042   2.5e+02     100     140 ..     129     169 ..     126     176 .. 0.83
   2 ?    8.5   0.0   0.00011      0.64     278     330 ..     351     406 ..     339     413 .. 0.85

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.042
                 GGGHHHHHHHHHHHHHHBHHHHHHHHHHHHHHHHHCCC--S CS
   MmgE_PrpD 100 sdvlpaalAvAealgasgkdlLtAivvGyEvqgrlglalsf 140
                  +++ +++A  ++ +++++d L+A+++++ ++g  +++l++
  EEA22381.1 129 VVNVDTVIAELQQGDQDSHDTLEAYALAISIAGATVAQLRL 169
                 667778889999999999***********999988877765 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00011
                 HHHHHHHHCCT..CCCEEEEEEEE-HHHHHHC---S.---SHHHHCT-CCHHHHHH CS
   MmgE_PrpD 278 alklraelklk..pddIesieirtseaalriigkkg.ppenradadhSlqyvvAva 330
                  +kl++  k++  ++d+++++i ++++ +++i ++   p++    d S+ + ++va
  EEA22381.1 351 HRKLHEAAKEQisVSDVQKVDIYITQHWMKMILWRLrSPSSSSSNDLSIAFPLSVA 406
                 4567777777688*********************9999***********9988887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (644 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       611  (0.0340789); expected 358.6 (0.02)
Passed bias filter:                      509  (0.0283898); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 4291.45
//
Query:       EEA22382.1  [L=327]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.6e-08   33.6   0.0    0.00048   19.7   0.0    2.1  2  Epimerase       NAD dependent epimerase/dehydratase family
    6.5e-05   22.9   0.0    0.00018   21.4   0.0    1.8  2  NAD_binding_10  NAD(P)H-binding
    0.00011   21.9   0.0      0.016   14.7   0.0    2.2  2  NmrA            NmrA-like family
     0.0034   17.8   0.0     0.0063   16.9   0.0    1.5  1  Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domai
     0.0036   16.5   0.0      0.016   14.3   0.0    1.8  1  RmlD_sub_bind   RmlD substrate binding domain
     0.0053   16.7   0.0     0.0096   15.8   0.0    1.5  1  KR              KR domain
     0.0053   16.2   0.1       0.56    9.5   0.1    2.1  2  GDP_Man_Dehyd   GDP-mannose 4,6 dehydratase
  ------ inclusion threshold ------
      0.015   14.3   0.0      0.043   12.8   0.0    1.7  1  3Beta_HSD       3-beta hydroxysteroid dehydrogenase/isomerase
       0.03   13.5   0.0       0.95    8.6   0.0    2.2  2  NAD_binding_4   Male sterility protein
       0.19   11.8   0.0       0.29   11.2   0.0    1.3  1  Shikimate_DH    Shikimate / quinate 5-dehydrogenase


Domain annotation for each model (and alignments):
>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.0   2.7e-07   0.00048       1      73 [.       4      79 ..       4     126 .. 0.79
   2 !   12.1   0.0   5.4e-05     0.097     161     228 ..     164     230 ..     148     235 .. 0.87

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 2.7e-07
                EEEETTTSHHHHHHHHHHHHCT.SEEEEEES-STTTTCHHCHHC..EEEE--TT-HHHHHHHHHHHT-SEEEE--S CS
   Epimerase  1 ilVtGatGfiGsalvkallekg.yevigldrlssasntarledl..elveldltdrsalerlfkeeqpdavihlAa 73
                il++GatG++G+ +++ l + g ++v g++r s++  + + +++   l+      +++    +++  +d+vi +A 
  EEA22382.1  4 ILILGATGYLGNRVANLLVQSGqHTVYGVARSSDKALQLAGDEItpVLCPDPANSPEQYLSTIRSSSIDIVIDCAQ 79
                89********************888*******77776666666653333333334446667777777777777766 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 5.4e-05
                 T-EEEEEEESEEESTTS-TTS.TTSHHHHHHHHHHTTS.SSEEEETTST-EEEEEEHHHHHHHHHHHHHH CS
   Epimerase 161 glnaiilrlfnlyGprngege.vsrvipalirkilegk.qevtllgdgtalRdflyveDvaeaillvleh 228
                  l+++ilr+  +yG     +   s++i+ + +   ++  +++ +  d +++  +++v+D a+a++ ++e+
  EEA22382.1 164 VLDVMILRPALVYGRQ---PAvWSSFIAPVFEATRNKTmESIQVPLDPKSRPGLVHVDDSATAFVKAVEK 230
                 6899***********9...444888888888887777788999999*********************998 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0     1e-07   0.00018       1      90 [.       8     107 ..       8     182 .. 0.62
   2 ?   -2.1   0.0       1.7   3.1e+03      21      54 ..     220     252 ..     214     261 .. 0.74

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 1e-07
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHHCTTTCEEEE--TT.-CCHHHHHHT..T-SEEEES---TCC.......HHHHHHHHHHHH CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpeklaeleaeeglevvegdvt.dvedlaealk..gadaVvsalggggk.......deegaknivdaa 85 
                     GAtG  G ++++ l+++g+h+v  ++R+++k+ +l+ +e + v+  d   ++e+  ++++   +d+V+ ++ + ++        +++ k  +da 
      EEA22382.1   8 GATGYLGNRVANLLVQSGQHTVYGVARSSDKALQLAGDEITPVLCPDPAnSPEQYLSTIRssSIDIVIDCAQALQQghsflenIKKVGKERLDAY 102
                     9********************************9*865444444456651579999999733567899888544442233222222344446666 PP

                     HHCT- CS
  NAD_binding_10  86 keagv 90 
                     k+ g+
      EEA22382.1 103 KARGT 107
                     66554 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.7
                     EEEEEETTHHHCHHHHCTTTCEEEE--TT-CCHH CS
  NAD_binding_10  21 evtalvRnpeklaeleaeeglevvegdvtdvedl 54 
                     + ta+v   ekl+ l a +g++ v   vt++e++
      EEA22382.1 220 SATAFVKAVEKLP-LIAGSGVHPVFDLVTSQESM 252
                     6799999999999.55578888877777777776 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.7   0.0   9.1e-06     0.016       1      34 [.       4      38 ..       4      99 .. 0.72
   2 !    5.2   0.0    0.0075        13     150     222 ..     185     257 ..     180     260 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 9.1e-06
                EEESSTTSHHHHHHHHHHHHHT.-EEEEEES-S-S CS
        NmrA  1 IlviGaTGrqGksvvrallkag.hkvralvRdtks 34
                Il++GaTG++G+ v++ l+++g h+v  + R +++
  EEA22382.1  4 ILILGATGYLGNRVANLLVQSGqHTVYGVARSSDK 38
                89******************762555566665544 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0075
                 SSS-SS-BEEE-TTS.-EEEEESS-TTS-EE.-HHHHHHHHHHHHHHHHHHHTTEEEEE-SEEE-HHH.HHHHHH CS
        NmrA 150 sllaqlkvgdtappedkvtllgpgnpkavll.daeeDiGafvikilkdprklkgkriklagntlsgne.ivelfe 222
                 s++a+ +    ++      ++ p +pk ++  ++++D +++ +k++++   + g+ +++  + ++ +e ++e+f+
  EEA22382.1 185 SFIAPVFEATRNKT--MESIQVPLDPKSRPGlVHVDDSATAFVKAVEKLPLIAGSGVHPVFDLVTSQEsMCEIFN 257
                 55566333333333..45688888888888888***************999999999999998876553788886 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.0   3.5e-06    0.0063       1      76 [.       3      80 ..       3     101 .. 0.65

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 3.5e-06
                    EEEEETTTSHHHHHHHHHHHCTSSEEEEEEEESTTTTTSBHHHHSG..GGTTTECEBEEEGGGGGCTT-SEEEE-SCH CS
  Semialdhyde_dh  1 kvaivGatGyvGqellrlLeehpevelvvllsssrsaGkklaeavk..aleegkdlkvedvdeeelkevdivflalpa 76
                    ++ i+GatGy G ++++lL ++ + ++  ++ ss +a +   +        + ++ + +  ++   +++div+ ++ a
      EEA22382.1  3 RILILGATGYLGNRVANLLVQSGQHTVYGVARSSDKALQLAGDEITpvLCPDPANSPEQYLSTIRSSSIDIVIDCAQA 80
                    578******************887777777666663333333333233222333333333455666788888888654 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   9.1e-06     0.016       2     184 ..       3     213 ..       2     253 .. 0.69

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 9.1e-06
                    EEEEESTTSHHHHHHHHHCTTTSEE.EEEE-TT.................T--TTSHHHHHHHHHHH--SEEEE------HHHHHHSHHHHHHHHT CS
  RmlD_sub_bind   2 kilvtGanGqlGseLakqlaeegle.vlaltre.................eldltdaeavaellkeakpdvvvnaAAytavDkaEseeeaayavna 79 
                    +il++Ga+G lG  +a++l ++g + v+++ r+                     + +e+  +++++ + d+v+++A   a  +  s  e+  +v  
     EEA22382.1   3 RILILGATGYLGNRVANLLVQSGQHtVYGVARSsdkalqlagdeitpvlcPDPANSPEQYLSTIRSSSIDIVIDCAQ--ALQQGHSFLENIKKVGK 96 
                    79****************9998754167777779999***999999998544466789999999***********94..55555555555555543 PP

                    HHH.HHHHHHHHHCT-EEEEEEEGGGS-S-.....TTS-B-TTS----SSHHHHHHHHHHHHHHH..H-SSEEEEEE-SEESSSS...S-HHHHHH CS
  RmlD_sub_bind  80 eav.ealAeaaaavgalLihvStDyVFdGe.....kkrpYeeddetsPlnvYGrtKlaGEqavla..agkkalivRtswvygekg...knfvktml 164
                    e   +  A+ +   +  +i+ S  +V   +       +   +d++t+P  +  + +++ E+a+l+  ++ +++i+R + vyg++     +f++ ++
     EEA22382.1  97 ERLdAYKARGTGGPKLGFIYCSGVWVHGSSnkavtDLDMVGPDAATQPAELV-AWRVDLENAILDshNVLDVMILRPALVYGRQPavwSSFIAPVF 191
                    3320333555555566788888888876664333222335567777777665.458899****995455699*********996511146666666 PP

                    HHH..HH-SEEEEESS-EE--E CS
  RmlD_sub_bind 165 rla..kereelkvvaDqlgsPT 184
                    +    k+ e+++v  D   +P 
     EEA22382.1 192 EATrnKTMESIQVPLDPKSRPG 213
                    5543355666777777666665 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.8   0.0   5.4e-06    0.0096       4      36 ..       5      39 ..       3      97 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.8 bits;  conditional E-value: 5.4e-06
                EEETTTSHHHHHHHHHHHHHHS-EEEEE-SS.... CS
          KR  4 litGGlGgLGlelarwlaekgarhlvllsRsa..a 36
                li G++G LG  +a+ l+++g++++  ++Rs+  a
  EEA22382.1  5 LILGATGYLGNRVANLLVQSGQHTVYGVARSSdkA 39
                9******************************5330 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.5   0.1   0.00031      0.56       1      32 [.       5      37 ..       5      48 .. 0.82
   2 !    4.8   0.0    0.0088        16     290     322 ..     271     303 ..     210     312 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00031
                   EEETTTSHHHHHHHHHHHHCT.-CCEEEEEEES CS
  GDP_Man_Dehyd  1 LiTGiaGfiGsylaelLlekg.yevhgivrrss 32
                   Li G +G+ G+ +a+lL++ g ++v+g+ r s+
     EEA22382.1  5 LILGATGYLGNRVANLLVQSGqHTVYGVARSSD 37
                   899****************97356778776554 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.0088
                    CCCEECGG--SS--SB--B-THHHHHHH----S CS
  GDP_Man_Dehyd 290 vvevdpkyfrpgevdlllgdaskakeeLgWkpk 322
                    +v  d   +r++  ++  g  ++a++ LgW+pk
     EEA22382.1 271 LVGHDDDIVRKAVSTTFRGSSARAEQLLGWQPK 303
                    566777888999889999**************8 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   2.4e-05     0.043       1     198 [.       5     192 ..       5     233 .. 0.70

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 2.4e-05
   3Beta_HSD   1 vvtGgaGFlGralvkeLvrleelkevrvlDlrespelleelskvnvkkviegDvtd.kdkleealegvdvvihlaslvdvag.kltedeimkvnvkGTr 97 
                 +++G++G+lG+++ + Lv+ ++ ++  v+ ++ s+ +  +l   +++ v++ D  +  ++    ++++++ i++ +++ +++ +   ++i kv     +
  EEA22382.1   5 LILGATGYLGNRVANLLVQSGQ-HT--VYGVARSSDKALQLAGDEITPVLCPDPANsPEQYLSTIRSSSIDIVIDCAQALQQgHSFLENIKKV----GK 96 
                 699******************6.44..56666665554455555666699999655167888999*********9999998735555656666....35 PP

   3Beta_HSD  98 nvleacvkagv..rv..lvYtSsaevvgpnslgeeilngdEeleyeslhqdaypesKalaEklvlkaNgrtlknggrlyTcaLRpagiyGegdkllvpl 192
                 + l+a +  g   ++  ++Y+S + v g    ++++++ d   +   +  + +   +   E+++l + +        l    LRpa +yG +  + + +
  EEA22382.1  97 ERLDAYKARGTggPKlgFIYCSGVWVHGS--SNKAVTDLDMVGPDAATQPAELVAWRVDLENAILDSHN-------VLDVMILRPALVYGRQPAVWSSF 186
                 66777666655223323899999999999..88999999999999999999999999999999999999.......35668999999999998887777 PP

   3Beta_HSD 193 lkqlak 198
                 +  +  
  EEA22382.1 187 IAPVFE 192
                 765433 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.0   0.00053      0.95       3      35 ..       8      39 ..       6      56 .. 0.85
   2 ?    2.7   0.0     0.033        59     189     227 ..     160     227 ..     154     248 .. 0.72

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00053
                   -TTSHHHHHHHHHHHHHS-.TEEEEEE-SSSHH CS
  NAD_binding_4  3 GaTGFLGkvLlekLLrttpevkiyllvRaksge 35
                   GaTG+LG+++ + L+++ ++ ++y ++R+++++
     EEA22382.1  8 GATGYLGNRVANLLVQSGQH-TVYGVARSSDKA 39
                   *********87777777765.*******99884 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.033
                    HHHHHH---EEEEEE-EEE-...............................-SSST---TTSHHHHHHHH CS
  NAD_binding_4 189 earrrsglpvvivRpsiitg...............................esktGwingsdlgirgllg 227
                    + +  + l v+i+Rp  ++g                               +s +G ++ +d  ++++++
     EEA22382.1 160 DSH--NVLDVMILRPALVYGrqpavwssfiapvfeatrnktmesiqvpldpKSRPGLVHVDDSATAFVKA 227
                    455..5799***********88888888888888888877777777777777777777777744444444 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   0.00016      0.29      14      54 ..       3      44 ..       1      81 [. 0.89

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00016
                  EEEEES-.SHHHHHHHHHHHCCT-CEEEEEESSHHHHHHHHH CS
  Shikimate_DH 14 kvlliGa.GemaelvakhLlakgvkkvvvaNRtlerakelae 54
                  ++l++Ga G ++++va+ L+++g + v  + R+ ++a +la 
    EEA22382.1  3 RILILGAtGYLGNRVANLLVQSGQHTVYGVARSSDKALQLAG 44
                  799***88********************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (327 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       392  (0.021864); expected 358.6 (0.02)
Passed bias filter:                      384  (0.0214178); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.54u 0.31s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 2097.79
//
Query:       EEA22383.1  [L=285]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00088   19.7   0.2     0.0024   18.3   0.2    1.8  1  GDPD_2    Glycerophosphoryl diester phosphodiesterase family


Domain annotation for each model (and alignments):
>> GDPD_2  Glycerophosphoryl diester phosphodiesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.2   1.4e-07    0.0024      12      30 .]     257     275 ..     247     275 .. 0.90

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 1.4e-07
      GDPD_2  12 vwrelvgaGVdgInTDdld 30 
                 +w+elv+aGVd++n Ddl+
  EEA22383.1 257 LWQELVDAGVDRLNVDDLE 275
                 8*************99985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (285 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       388  (0.0216409); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 1938.77
//
Query:       EEA22384.1  [L=104]
Description: hypothetical protein PMAA_061620 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (104 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       524  (0.0292264); expected 358.6 (0.02)
Passed bias filter:                      424  (0.0236488); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.44
# Mc/sec: 717.81
//
Query:       EEA22385.1  [L=112]
Description: hypothetical protein PMAA_061630 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (112 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       239  (0.0133304); expected 358.6 (0.02)
Passed bias filter:                      219  (0.0122148); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.26s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 819.03
//
Query:       EEA22386.1  [L=394]
Description: aspergillopepsin F precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.9e-52  178.7   0.0    2.2e-52  178.4   0.0    1.0  1  Asp              Eukaryotic aspartyl protease
    2.8e-06   27.9   0.0       0.15   12.8   0.0    2.9  2  Asp_protease_2   Aspartyl protease
     0.0072   16.6   0.0        1.2    9.3   0.0    2.7  3  TAXi_N           Xylanase inhibitor N-terminal
  ------ inclusion threshold ------
      0.015   15.9   0.0        2.5    8.7   0.0    2.8  2  gag-asp_proteas  gag-polyprotein putative aspartyl protease


Domain annotation for each model (and alignments):
>> Asp  Eukaryotic aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  178.4   0.0   4.9e-56   2.2e-52       2     313 ..      84     391 ..      83     393 .. 0.89

  Alignments for each domain:
  == domain 1  score: 178.4 bits;  conditional E-value: 4.9e-56
                 EEEEEEETTTTEEEEEEEETT--SEEEEBTTESTSHCHHTSS-B-GGG-TT-EEEEEEE.EEECTTSEEEEEEEEEEEEETTEEEEEEEEEEEEEESSH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp   2 YfgeisiGtpeqkftvifDTGSsdlWVpsskckkssackshstydpskSstykkngksl.sisYGdgsvsGflsqdtvkvggltvknqefgeatkepgs 99 
                 Y+++i+iG +   ++v +DTGSs+lWV   ++       +h tydp+    +   g+++ +i+  d + +G ++qd+v vg l  +nq+++ ++  + +
  EEA22386.1  84 YLTPIQIGAS--VLQVALDTGSSNLWVYTPDTP---GIGTHATYDPQT--GRLMPGYRWhAINGIDIEFKGRVFQDNVRVGHLRYPNQAVQVVDMIKPE 175
                 99******98..9**************999886...899*******85..55679999955665566************************99987766 PP

                 HHTTSS...SSEEEE-S-GGGSCGG...SCCHHHHHHHTTSSSSSEEEEEE-STTSSEEEEEESSEEGGGEEEEEEEEEESS.TSSTEEEEEEEEETTE CS
                 xxxxxx...xxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxx RF
         Asp 100 tflaak...fdGiLGlgfkeisvee...atpvfdnlvsqglikepvfsvylnreeeeggeivfGgvDeskykGsltyvpvts.kgywqielesvtvggk 191
                 + ++ +   +dGiLGl+f++ ++++   ++++f n++++  ++ pvf+  l   +   g+  fG +D++kyk +l+++p+++ kg w+i++++++vgg+
  EEA22386.1 176 SSMHNPlrnNDGILGLAFSSRNSVRpikQNTFFANIKDK--LDIPVFAACLK--HGVPGTFDFGWIDSQKYKEKLFWMPIDNsKGLWNITIDGFSVGGD 270
                 6666544559***********99998878888***9987..999*******5..99*************************98999************* PP

                 EEEEEEEEEEEEETTCSSEEEEHHHHHHHHHHHTTEE.EETTCEEEEETTGGGGSEEEEEEETTEEEEEEGGGGEEEESSSTTSEEEESEEECCTSSSE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp 192 tvlcssgcqailDtGTsllalptsivekiakaigakk.sesegeyvvdCdslsslpdisftiggakitvpvselvlkeeeseesqCilglvseeegdlw 289
                  + +s+ ++ai+DtGTs+  ++++iv+k+ ++i  ++ s  +g y++ C   s+ pd+++++g+ +  ++ + + + ++    + C+ g+++++++d++
  EEA22386.1 271 PF-NSNPFHAIVDTGTSINLFQENIVKKYYEKIPDSSfSILNGGYTFPCTPASTIPDFNLKLGQYTAVISGKFIKYMSNG---THCYGGIQTSPNSDYN 365
                 *9.9****************************9766515568*********************99999998876666553...58************** PP

                 EEEHHHHTTEEEEE..ETTTTEEEEE CS
                 xxxxxxxxxxxxxx..xxxxxxxxxx RF
         Asp 290 iLGdvFlrsayvvf..dldnnrvglA 313
                 +LGdvFl+s+yv+f  d  n ++ +A
  EEA22386.1 366 VLGDVFLKSYYVIFfdDNINPQIAIA 391
                 ***********988544567777777 PP

>> Asp_protease_2  Aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.8   0.0   3.3e-05      0.15       3      90 .]      88     193 ..      86     193 .. 0.72
   2 !   11.7   0.0   7.1e-05      0.32       6      40 ..     273     307 ..     259     336 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 3.3e-05
  Asp_protease_2   3 vtinGkpvrfllDTGasttlispelaeklglkvreseltvrv.sg.....agg.e.vkarlvrldslklggltlknvpalvld..........lg 79 
                     ++i+   +++ lDTG+s++ + +     +g + + ++ t r+  g     ++g +  ++ +v  d++++g l+ +n+++ v+d          + 
      EEA22386.1  88 IQIGASVLQVALDTGSSNLWVYTPDTPGIGTHATYDPQTGRLmPGyrwhaINGiDiEFKGRVFQDNVRVGHLRYPNQAVQVVDmikpessmhnPL 182
                     566666789999*****9999999998888877666433333122333326775446678888889*****************998887755433 PP

  Asp_protease_2  80 eeidglLGmdf 90 
                     ++ dg+LG+ f
      EEA22386.1 183 RNNDGILGLAF 193
                     5779****876 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 7.1e-05
  Asp_protease_2   6 nGkpvrfllDTGasttlispelaeklglkvresel 40 
                     n  p+++++DTG s +l  +  ++k   k  +s++
      EEA22386.1 273 NSNPFHAIVDTGTSINLFQENIVKKYYEKIPDSSF 307
                     5689*********************9888887753 PP

>> TAXi_N  Xylanase inhibitor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.0   0.00027       1.2       1      29 [.      84     110 ..      84     131 .. 0.85
   2 !    4.3   0.0    0.0097        44      94     154 ..     147     210 ..     136     235 .. 0.57
   3 ?   -2.1   0.0      0.84   3.8e+03      12      27 ..     275     290 ..     269     306 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00027
      TAXi_N   1 YlvsisiGtppqplklvvDtGsdltWvqC 29 
                 Yl+ i+iG     l++++DtGs+ +Wv  
  EEA22386.1  84 YLTPIQIGAS--VLQVALDTGSSNLWVYT 110
                 9999****97..899***********965 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.0097
      TAXi_N  94 GvlatdtltlsstdgksvkvpnlvfGCgksnlgglaagadGilGLGrgklSlvsqlaskg...s 154
                 G + +d++++   + +++ v+ + +   +s+ ++  ++ dGilGL++++   v  +++++   +
  EEA22386.1 147 GRVFQDNVRVGHLRYPNQAVQVVDMIKPESSMHNPLRNNDGILGLAFSSRNSVRPIKQNTffaN 210
                 666666666644444444444333333333344444569*******998776666665553442 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 0.84
      TAXi_N  12 qplklvvDtGsdltWv 27 
                  p+ ++vDtG ++  +
  EEA22386.1 275 NPFHAIVDTGTSINLF 290
                 68999*****887655 PP

>> gag-asp_proteas  gag-polyprotein putative aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.0     0.014        63       3      89 ..      88     193 ..      86     196 .. 0.67
   2 ?    8.7   0.0   0.00056       2.5       5      31 ..     272     298 ..     271     319 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.014
                      EEETTEEEEEEEETT-SS-EEEHHHHHHTTGGGGEB..TT--......EE-TTST.T-.EEEEEEEEEE.EETTEEEEEEEEEESSSSE..... CS
  gag-asp_proteas   3 vkingkpvkflvDTGAsstiiseelaerlglsrkedkgkvev......ktangev.ea.krvrldsvkiggielrnvsavvlegelddl..... 83 
                      ++i    +++ +DTG s+  + + +   +g +   d++++++      +  ng   e  +rv  d+v++g+++  n  + v++  + ++     
       EEA22386.1  88 IQIGASVLQVALDTGSSNLWVYTPDTPGIGTHATYDPQTGRLmpgyrwHAINGIDiEFkGRVFQDNVRVGHLRYPNQAVQVVDMIKPESsmhnp 181
                      5666677888999999999998888888888888887776666666667777743233257777889999999988888888755422223455 PP

                      ......EEEHHH CS
  gag-asp_proteas  84 ......LLGldf 89 
                            +LGl f
       EEA22386.1 182 lrnndgILGLAF 193
                      555555777765 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.00056
                      ETTEEEEEEEETT-SS-EEEHHHHHHT CS
  gag-asp_proteas   5 ingkpvkflvDTGAsstiiseelaerl 31 
                      +n +p++++vDTG s  + +e+++++ 
       EEA22386.1 272 FNSNPFHAIVDTGTSINLFQENIVKKY 298
                      5899***********999999998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (394 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       357  (0.0199119); expected 358.6 (0.02)
Passed bias filter:                      328  (0.0182944); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2753.03
//
Query:       EEA22387.1  [L=397]
Description: hypothetical protein PMAA_061650 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       808  (0.0450667); expected 358.6 (0.02)
Passed bias filter:                      535  (0.0298399); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2713.79
//
Query:       EEA22388.1  [L=68]
Description: hypothetical protein PMAA_061660 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      0.005   16.6   0.1      0.057   13.2   0.0    2.0  2  FluMu_N   Mu-like prophage FluMu N-terminal domain


Domain annotation for each model (and alignments):
>> FluMu_N  Mu-like prophage FluMu N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.2   0.0   3.2e-06     0.057       7      21 ..      30      45 ..      24      48 .. 0.72
   2 ?    1.7   0.0     0.013   2.3e+02      16      27 ..      50      61 ..      50      68 .] 0.84

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 3.2e-06
                S-S----SS.S---SS CS
     FluMu_N  7 ahdGYRRAG.falpkg 21
                +++G+RRAG +al++g
  EEA22388.1 30 SKNGFRRAGaIALQNG 45
                49*******5566665 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.013
                S---SSEEE--- CS
     FluMu_N 16 falpkgentlpd 27
                f l+kg+n ++d
  EEA22388.1 50 FLLKKGKNVFDD 61
                5799******98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (68 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       181  (0.0100954); expected 358.6 (0.02)
Passed bias filter:                      167  (0.00931452); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.26s 00:00:00.65 Elapsed: 00:00:00.43
# Mc/sec: 479.40
//
Query:       EEA22389.1  [L=2388]
Description: polyketide synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.4e-78  262.1   0.0    9.7e-78  261.2   0.0    1.4  1  ketoacyl-synt    Beta-ketoacyl synthase, N-terminal domain
      1e-56  191.7   0.2    2.4e-56  190.5   0.2    1.7  1  KR               KR domain
    3.7e-52  177.4   0.8    7.4e-52  176.4   0.8    1.5  1  PS-DH            Polyketide synthase dehydratase
    2.5e-47  162.0   0.1    5.2e-47  160.9   0.1    1.5  1  Acyl_transf_1    Acyl transferase domain
      8e-34  116.2   0.5    4.6e-33  113.7   0.5    2.4  1  Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
    1.2e-18   67.6   0.0    3.4e-18   66.1   0.0    1.9  1  KAsynt_C_assoc   Ketoacyl-synthetase C-terminal extension
    2.6e-17   63.0   0.1      2e-16   60.1   0.0    2.6  3  ADH_zinc_N       Zinc-binding dehydrogenase
    1.1e-14   55.7   0.0    8.8e-14   52.7   0.0    2.7  2  ADH_zinc_N_2     Zinc-binding dehydrogenase
      1e-13   51.2   0.1      8e-13   48.3   0.0    2.5  2  adh_short        short chain dehydrogenase
    1.1e-06   28.4   0.0    2.8e-06   27.0   0.0    1.7  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    3.9e-06   26.7   0.1    9.6e-06   25.4   0.1    1.6  1  ADH_N            Alcohol dehydrogenase GroES-like domain
    1.5e-05   25.2   0.0      7e-05   23.1   0.0    2.2  2  PP-binding       Phosphopantetheine attachment site
    0.00054   19.4   0.0     0.0015   18.0   0.0    1.7  1  Thiolase_N       Thiolase, N-terminal domain
  ------ inclusion threshold ------
      0.026   14.6   0.0        5.9    7.0   0.0    2.6  2  Shikimate_DH     Shikimate / quinate 5-dehydrogenase
       0.12   12.1   0.1       0.32   10.8   0.1    1.7  1  PH_17            PH domain


Domain annotation for each model (and alignments):
>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  261.2   0.0   8.1e-81   9.7e-78       2     253 .]       9     257 ..       8     257 .. 0.93

  Alignments for each domain:
  == domain 1  score: 261.2 bits;  conditional E-value: 8.1e-81
                    --EEEEEEEEEBTTBSSHHHHHHHHHTT---EEES-TTSSCGTTSBTSSTTEEE-BSS.EEE..S..TTEGGTTSTHHHHHHHCTS-HHHHHHHHH CS
  ketoacyl-synt   2 epvaivGmgarfPggndveefwelLlegrdaiselpadrwdadklydpparaagkiktklggfld..vddfdpeffgispreaeamdpqqrlllea 95 
                    e vai+G+++rfPgg+++e+fw+ L+eg++a se++++r+ ad++  +++r  + i+   + fl+   ++fd+ ffgis+ ea +mdpq+r+++e+
     EEA22389.1   9 ETVAITGLACRFPGGHNLESFWQFLCEGKSAWSEMDSSRFHADAFWSEEKRRNKSITGG-AHFLKqdFASFDANFFGISATEAGSMDPQHRIMIEV 103
                    78*******************************************98888888888885.556665889*************************** PP

                    HHHHHHHHTS-HHTCTTGGEEEEEEESSTHHHHHHHHHHHTTGGGSCTTHHHHHSTTHHHHHHHHHHT--SSEEEEESGGGHHHHHHHHHHHHHHT CS
  ketoacyl-synt  96 awealedagltpeeldgsrvgvfiGvgagdyaalaaldedgsevkaspkavgavlanviagrisyalglrGpsvtvdtACsSslvavhaavqslrs 191
                    a+eale ag+t e+l g+r+gvf+G   +d++++   d ++    +++ a+g  la+  a+ris+ ++lrGps++vdtACsSslva+h+a+qsl++
     EEA22389.1 104 AYEALETAGYTLEDLAGTRTGVFMGHFTSDWKDTMYRD-AD-AAPQYS-ATGP-LASSFANRISWLWNLRGPSFCVDTACSSSLVALHLACQSLHT 195
                    *******************************8744433.33.467777.8998.****************************************** PP

                    TS-SEEEEEEEE---SHHHHHHHHHTTBB-TTSGGGTTBTTB-SB-BB-EEEEEEEEECHHH CS
  ketoacyl-synt 192 geadvalaGGvellltpeavagfsaagllspdgrckafdpkadGfvlGEGvGavvLkrleda 253
                    +e+d+a++GG++ll++p  + ++s +++lspdg+ck+fd++a+G+ +G+G +a++Lkr+ da
     EEA22389.1 196 RESDIAIVGGSNLLINPDMFLFLSGQNFLSPDGKCKPFDASANGYGRGDGFAAIILKRAGDA 257
                    **********************************************************9776 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  190.5   0.2     2e-59   2.4e-56       1     180 []    2012    2189 ..    2012    2189 .. 0.99

  Alignments for each domain:
  == domain 1  score: 190.5 bits;  conditional E-value: 2e-59
                  SEEEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------T CS
          KR    1 gtylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdkll 97  
                  ++y+++GGlGgLG++la  l+e+gar+l +lsRs+a++ ++++l++el+a+g++  ++++Dvs + +++++l+++ ++ +p++Gvi++A+vlrd+l+
  EEA22389.1 2012 ASYVLVGGLGGLGRSLASLLVENGARKLCFLSRSGAKTLEAQRLMQELSASGVQALALECDVSVAVSLREALAKCVKDLGPVNGVIQCAMVLRDTLF 2108
                  68*********************************************************************************************** PP

                  TT--HHHHHHHHTTTTHHHHHHHHHTTTS--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHHHHHTEEEEEE--BTT CS
          KR   98 eemtaedleqvlapKvkGawnLhelledesldffvlfSSiagllgsagqanYaaaNaflDalaeyrrsqglpavsinwglwae 180 
                  ++mt  ++ ++++pKv+G+wnLh  l+d  ++ff+++SS ag++g++gq+nYaaa af+Dala+ rrsq+ +++s+++g++++
  EEA22389.1 2109 TNMTYMQWVECTRPKVQGTWNLHVELPD--VNFFIVLSSFAGIFGNRGQSNYAAAGAFQDALAHLRRSQNKKGLSLDLGIMRD 2189
                  **************************95..*************************************************9975 PP

>> PS-DH  Polyketide synthase dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  176.4   0.8   6.2e-55   7.4e-52       2     291 ..     942    1251 ..     941    1256 .. 0.87

  Alignments for each domain:
  == domain 1  score: 176.4 bits;  conditional E-value: 6.2e-55
                  TTB.-EE--.-SS-EEEEEEE-S-SS.TTTSEEETTEEB--TTHHHHHHHHHHHHTS---....-EEEEEEEE----.B--SS.-EEEEEEEEE-TT CS
       PS-DH    2 pllGsrvrsasdkevvfrnrlrlaelpwLrDHrvdgkvvlPgagylemaleAarqltges...kavelrdvsilkalvlpede.pvevqlslepeed 94  
                  +llGsr++  +++e+v+r ++rl+e pw+ DH+++g++++P+ag+l+ma+eAa + + ++   +++ lr++++ +a+++++d+ +ve +++l+p+ +
  EEA22389.1  942 RLLGSRMSAVAAEEHVWRGHIRLSEEPWVSDHKIHGSILYPAAGFLAMAIEAALESADTTrqvTGLYLREIQFVAAMIVAPDSdGVEYTIILRPHLS 1038
                  79*****************************************************99988888999*************99999***********88 PP

                  S-E.......EEEEEEE-SS-TT.EEEEEEEEEE-----..--B--HHHH.HHHS-SEE....E-.......HHHHHHHHHHHSEEE-GGG--EEEE CS
       PS-DH   95 gad...rawvefeifSregggeewtehatGtvrlaegaa..aaavdleal.qarcaepaslrsvs.......saefYerlaargleyGpsFqglral 178 
                  g+    +aw+ef+++S  +g++  t ++ G +++  +    +++v+ e + +++++ + ++ +vs        ++fY++l++ gl+yG++F+++++l
  EEA22389.1 1039 GTRgttSAWMEFSVASSPDGSS-LTQNCLGLIQVKYDVSnqREDVTRELRlKDEKTVEQYQDAVSvckvvrhTKDFYTKLDSLGLNYGEAFRNVTEL 1134
                  777999***************9.8*********999988773333333332444555555555556666666788********************** PP

                  EEETTEEEEEE---....GGGSSTTTT-SB-HHHHHHHHHHG..GG----------EEEEEEEEEEE-S...-BTS--EEEEEE......----SS- CS
       PS-DH  179 wrgdgealaelrlp....eelaggesayvlhPallDaalQllaaalsaeaekadaaylPvaierlrvyrpssaageelwvharl......eeegars 265 
                  +++ g+ l+++++p    +  +++++++v+hP++lDa+++l +aa    a++ +++++P ++ +l v       ++++++ha+l      +++g ++
  EEA22389.1 1135 HSRMGQSLGTVTIPdaglNPNKRQRRPHVVHPTTLDAVFHLAFAAT--TANELRQPMVPRFLAELFVAV-----DMPFTAHAQLkgfstsAKHGLKE 1224
                  **************7555444444455*************665655..479****************85.....6779999999999988999999* PP

                  EEEEEEEE-.SS-BEEEEEESEEEEE- CS
       PS-DH  266 ivadltlvd.edGrvvaeieglrlrrv 291 
                  ++ad+ ++d  + r+v++++gl++  v
  EEA22389.1 1225 LRADINILDeTQTRPVLTVTGLTCAEV 1251
                  *********66779*********9776 PP

>> Acyl_transf_1  Acyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  160.9   0.1   4.4e-50   5.2e-47       2     299 ..     551     872 ..     550     885 .. 0.82

  Alignments for each domain:
  == domain 1  score: 160.9 bits;  conditional E-value: 4.4e-50
                    EEE--TT---TTTTCCHHHC-HHHHHHHHHHHHHCCHHHT--...HHHHHHS--TTGGGSHHHHHHHHHHHHHHHHHHHHHTT-TTSEEEE-TTHH CS
  Acyl_transf_1   2 fvfsGqGsQwaGMGmeLlktskafaaviaradeafksqygfs...vldvlrnnpeglldaiqfvqpaLaavqialaellkskGvrpaavvGHSlGE 94 
                    f+f+GqG+Qw GMG++L++  ++f+ ++++ade ++ q   +   v ++ r + ++ + +   +q   +++q+al++ l+    +p av+GHS GE
     EEA22389.1 551 FIFTGQGAQWPGMGAQLMDF-PVFRSSVEAADEYLRTQLSCKwsaVEELKRGKATSRVGDALYSQALCTILQVALIDMLNHWSIKPVAVAGHSSGE 645
                    9*******************.****************987652233444455556777788888999999************************** PP

                    HHHHHHCCSSSHHHHHHHHHHH...HHHHHHHT..S-EECCEECS.....HHHHHHH....TT.EEEEEEECCCCECCEEHHHHHHHHHHHHHCC. CS
  Acyl_transf_1  95 lAaavvagalsseeallavvlr...srlmmqla..gpgdmaavel....aeeeeklr..cqddvvgavansprrvvisgsqealrelvervskegv 179
                    + aa+ ag l+ e+a ++++ r   s+  + +   ++g+m av+     a e    r  ++ +v +a++nsp++v++sg  e++++l +  s++g+
     EEA22389.1 646 IGAAYCAGYLTREDAWKVAYERgivSGSLKTIVpeLQGAMMAVGTspekA-ESFIERacQNGEVGVACVNSPSSVTLSGDAESIDKLETMFSEAGI 740
                    ********************99333344555544689*******977532.2222334256689******************************** PP

                    CCEEECCCEECTTCCCCCCCCHHHHHHHHCCCHHCHHTTBEHCCCHHH...HHHCHHHHHHHHHHHCHCCHCCHHTTS..........SSECC-CC CS
  Acyl_transf_1 180 galvenvnvavhspqvdaiadalasaladiaprkpkvakisstsldes...serelsaeywvanlrspvrfaeavlsa..........aetiplvf 262
                    +a++ +v+ a hs  + ++a + ++ +adi+p +  + +i   s+      s++el a ywv+nl spv+fa+av+++           e + +v 
     EEA22389.1 741 FARKLRVDTAYHSHHMHRVARDYLERIADIRPITQSLRDITMHSSVIPgivSPGELGAGYWVRNLISPVQFAQAVQNLvrpmvdgkhsTENAVDVL 836
                    *****************************9988776655543333222455************************98765543333334667789* PP

                    EECSSSSCCHCCCCCCCHHGGG-TCCCCCCTEETTSS CS
  Acyl_transf_1 263 veispHslllaalektlksaedvksatlvGklkrdlt 299
                    vei pH+ l+    + lk   +v ++  + +l r+ +
     EEA22389.1 837 VEIGPHPALQGPSTQSLKG-IGVTNMDYLSTLVRNAN 872
                    **********999999994.66666666666666655 PP

>> Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.7   0.5   3.8e-36   4.6e-33       2     116 ..     266     381 ..     265     382 .. 0.98

  Alignments for each domain:
  == domain 1  score: 113.7 bits;  conditional E-value: 3.8e-36
                      EEEEEEEEEE--STSSSTSTTHHHHHHHHHHHHHHHT--GGGEEEEE-SS-SSHHHHHHHHHHHHHHHGGGGG.SCTSEEE-THHHH-B-GGGH CS
  Ketoacyl-synt_C   2 avikgsavnsdgahnsltapngeaqaraiekalaeagvdpedvdyveahgtgtplgDpiElealkkvfgekar.kqplavgSvKsniGHleaAa 94 
                      a i+g++vn+dg+++ l  p+++aqa++i +++++ag+d ++  y eahgtgt++gD+ E+ al++++++ +  +q+l +gSvK niGH+eaAa
       EEA22389.1 266 AMIRGTGVNQDGHTKALFLPSADAQAELISEVYRSAGLDFRETMYAEAHGTGTQAGDAEEALALSRTLSAPGVrNQKLLLGSVKGNIGHTEAAA 359
                      89******************************************************************99877899****************** PP

                      HHHHHHHHHHHHHHTEE--BTT CS
  Ketoacyl-synt_C  95 Gvaelikvvlalkhgvipptln 116
                      G+a++ik vl+l+hg+ippt+n
       EEA22389.1 360 GIASVIKGVLMLEHGIIPPTIN 381
                      ********************98 PP

>> KAsynt_C_assoc  Ketoacyl-synthetase C-terminal extension
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.1   0.0   2.8e-21   3.4e-18       1     111 [.     385     519 ..     385     520 .. 0.87

  Alignments for each domain:
  == domain 1  score: 66.1 bits;  conditional E-value: 2.8e-21
  KAsynt_C_assoc   1 PnpeipaleegrlkVvteptpwpggi...vgvNsfGfGGsnvHviLksnk.......kekrkeesk.....................eeslprLl 64 
                     Pnp+i+ +++ +l+V t+ tpwp +     ++N+ G+GG+n+H++L+ +        k                              +++prL+
      EEA22389.1 385 PNPKID-FDTYQLRVQTKLTPWPTDGvrrLSINACGYGGTNAHAVLEDAYhylqsrgK-------ItphftkeglvhrlksssynerAKPTPRLI 471
                     9*****.****************998889*******************9956555440.......334455566677777777777789****** PP

  KAsynt_C_assoc  65 vlsgrteeaveallekleeh.lldaellsllneilseeisrlpyRGya 111
                     ++s+++ ++++++ ++l+++ +l+ + l+ l+++ s+++srl+++ ++
      EEA22389.1 472 PISAQDRDGLKRVKSSLANYvRLKTPNLDDLAYTISSKRSRLQWKTFV 519
                     ********************99999*******************9996 PP

>> ADH_zinc_N  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.0         9   1.1e+04      67      91 ..    1397    1421 ..    1372    1437 .. 0.77
   2 !   60.1   0.0   1.7e-19     2e-16       1     108 [.    1811    1921 ..    1811    1942 .. 0.89
   3 ?   -2.2   0.1       3.1   3.7e+03      10      39 ..    2066    2097 ..    2064    2105 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 9
                  CSHHHHHHHHHCEEEEEEEEECSCT CS
  ADH_zinc_N   67 GsgatleaalkllkpgGrlvvvGgg 91  
                   s++t e    llkpgG+l + G +
  EEA22389.1 1397 TSPQTDEKVKPLLKPGGKLCLLGDV 1421
                  45666666777999***99999954 PP

  == domain 2  score: 60.1 bits;  conditional E-value: 1.7e-19
                  HHHHHHHHHHHHTT-EEEEEESSHHHHHHHHH.TT..ESEEEETTTC.HHHHHHHHHTTTSSEEEEEESSCSHHHHHHHHHCEEEEEEEEECSC..T CS
  ADH_zinc_N    1 gvGlaavqlAkalGaeviavdsseeklelakk.lG..adevinykea.dlverikeltggegvdvvfecvGsgatleaalkllkpgGrlvvvGg..g 91  
                  gvG+ a+q+A ++G ev+++++s+ k+el++  +G   d+++n+ ++ ++ + i+++tgg+gvdvv++ +  g++l++   +++p G +  +G+   
  EEA22389.1 1811 GVGQSAIQVAQHFGLEVFVTVGSKAKRELVRNeYGipDDHIFNS-RDlSFADGIRRMTGGKGVDVVLNSLT-GEALRETWHCIAPFGYFIEIGLkdI 1905
                  9******************************99**766999999.666***********************.**********************988 PP

                  SSEEEEEHHHHHHTT-E CS
  ADH_zinc_N   92 kgeeefdlrnlllkeks 108 
                  + ++ +d++++ +++++
  EEA22389.1 1906 QANTRIDMAPF-ARNVT 1921
                  88888999996.44554 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 3.1
                  HHHTT-EEEEEESSHHHH.HHHHHTT.ESEEE CS
  ADH_zinc_N   10 AkalGaeviavdsseekl.elakklG.adevi 39  
                  A al + v +++s +e l + +k+lG ++ vi
  EEA22389.1 2066 ALALECDVSVAVSLREALaKCVKDLGpVNGVI 2097
                  67899988886666666615556699888887 PP

>> ADH_zinc_N_2  Zinc-binding dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       6.8   8.1e+03      31      79 ..    1394    1440 ..    1380    1449 .. 0.62
   2 !   52.7   0.0   7.4e-17   8.8e-14       4     131 ..    1849    1984 ..    1848    1986 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 6.8
                    H...HHHH.HHHHHHEEEEEEEEE----.S-EEE-CHHHCTTT-EEEE--GG CS
  ADH_zinc_N_2   31 g...gealleaslkvlpggGrlvsiggpplsaallkpakkrkgrsvkyeflf 79  
                        ++++ e++  +l++gG+l+ +g+       + ++ +++ +sv +++l+
    EEA22389.1 1394 MtvtSPQTDEKVKPLLKPGGKLCLLGD-----VKNTRTIEERLHSVGFSTLV 1440
                    3344666757777888888***99885.....24444444555555555555 PP

  == domain 2  score: 52.7 bits;  conditional E-value: 7.4e-17
                    SEEEETTSTTHH....HHH-TT-EEEEEES-HHHHH.HHHHHHEEEEEEEEE--.--.S-EEE-CHHHCTTT-EEEE--GGG...-.....-HHH CS
  ADH_zinc_N_2    4 devidyrtedfe....aatggegvDvvldtvggealleaslkvlpggGrlvsig.gpplsaallkpakkrkgrsvkyeflfsmkas....aqadi 89  
                    d+++++r+ +f+    + tgg+gvDvvl+++ geal +++++++++ G +++ig +++ +++  + a ++++ ++++  l  + a+      a i
    EEA22389.1 1849 DHIFNSRDLSFAdgirRMTGGKGVDVVLNSLTGEAL-RETWHCIAPFGYFIEIGlKDIQANTRIDMAPFARNVTFSFFNLN-LIAReqpeLFAAI 1941
                    8999***********999*****************9.*******999*******888844444455555766677766666.4444568888888 PP

                    HHHHHHHHHHHH----EEEE.EEGGGHHHHHHHHHSS--SSEE CS
  ADH_zinc_N_2   90 leelaalieeGklrpvvdrv.fpleeaaeAhrylesgrarGKi 131 
                    +e  ++++e G  rpv     +++ ++  A+r++++g+++GKi
    EEA22389.1 1942 IENTFDFLERGITRPVTPVItYSIGDIEGAFRLMQTGKHVGKI 1984
                    9***********999988656*********************8 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0       1.1   1.3e+03       3      43 ..    1803    1843 ..    1801    1865 .. 0.83
   2 !   48.3   0.0   6.7e-16     8e-13       4     160 ..    2015    2169 ..    2013    2179 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 1.1
                  EEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHH CS
   adh_short    3 vlvtGassGIGraiakelakeGakvvvvdrseekleevake 43  
                  +l+  a++G+G+   +     G +v+v+  s++k e v +e
  EEA22389.1 1803 ILIHAAAGGVGQSAIQVAQHFGLEVFVTVGSKAKRELVRNE 1843
                  8999***********************87777777666665 PP

  == domain 2  score: 48.3 bits;  conditional E-value: 6.7e-16
                  EEESTTSHHHHHHHHHHHHTT-EEEE.EESCHHH...HHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGC CS
   adh_short    4 lvtGassGIGraiakelakeGakvvv.vdrseek...leevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfsel 96  
                  + +G+ +G+Gr +a  l+++Ga+ ++ ++rs +k   ++++++el + g +ala+++Dv+ + +++++++k+vk+lg+++ ++++A + +++ f ++
  EEA22389.1 2015 VLVGGLGGLGRSLASLLVENGARKLCfLSRSGAKtleAQRLMQELSASGVQALALECDVSVAVSLREALAKCVKDLGPVNGVIQCAMVLRDTLFTNM 2111
                  578999******************999999988722245667777777************************************************* PP

                  SHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHH CS
   adh_short   97 seeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavaglt 160 
                  +  +w ++    ++g+ +l  ++ +          +  sS ag  ++ g++ Y+A+ a+ ++l+
  EEA22389.1 2112 TYMQWVECTRPKVQGTWNLHVELPDV------NFFIVLSSFAGIFGNRGQSNYAAAGAFQDALA 2169
                  *******************9995444......367999*****************977766665 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.0   0.0   2.4e-09   2.8e-06       4     132 ..    2021    2149 ..    2018    2175 .. 0.79

  Alignments for each domain:
  == domain 1  score: 27.0 bits;  conditional E-value: 2.4e-09
                    TSHHHHHHHHHHHTT-E.EEEEESSGGHHHHHHHHHHHTTSE.E....EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-H CS
  adh_short_C2    4 sgIGraiAkalaeeGae.vvltdlneeakkrveelaeelgae.v....lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsr 92  
                     g+Gr +A +l e+Ga+ +++  ++ ++  ++++l +el+a+ v    lecDV+   +++++ +++v+++g +++++ +a + ++  + f++++ 
    EEA22389.1 2021 GGLGRSLASLLVENGARkLCFLSRSGAKTLEAQRLMQELSASgVqalaLECDVSVAVSLREALAKCVKDLGPVNGVIQCAMVLRD--TLFTNMTY 2113
                    599*************76999999999988999999999866644568********************************99999..******** PP

                    HHHHHHHHHHTHHHHHHHHHHHHHCTSCCEEEEEEEGGGT CS
  adh_short_C2   93 eefdraldvnlyslfllakaalplmkeggsivnlssvgae 132 
                     ++ +    +++++++l  ++     +    + lss+++ 
    EEA22389.1 2114 MQWVECTRPKVQGTWNLHVEL----PDVNFFIVLSSFAGI 2149
                    ****99999999999886554....233345555555544 PP

>> ADH_N  Alcohol dehydrogenase GroES-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.4   0.1     8e-09   9.6e-06       2      64 ..    1694    1751 ..    1693    1790 .. 0.85

  Alignments for each domain:
  == domain 1  score: 25.4 bits;  conditional E-value: 8e-09
                  TEEEEEEEEEEE-HHHHHHHTTSTTTTSSSSEE---EEEEEEEEESTT-CS--TT-EEEE-SE CS
       ADH_N    2 gevlikvkaagiCgsDlhilkggkelevklplilGHEivGeveevgpevkklkvGdrVvvepl 64  
                  +e+ ++vka++++  +++++ g     + ++  lG +++G+v+ vg++v+k+kvGdrVv+  +
  EEA22389.1 1694 DEIEVQVKATSLNFREVMVVMG-----QIPDTLLGFDAAGVVKRVGSSVDKFKVGDRVVMCEH 1751
                  799*****************99.....4677899*************************9433 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       6.3   7.5e+03      10      33 ..    1490    1513 ..    1484    1514 .. 0.78
   2 !   23.1   0.0   5.8e-08     7e-05       2      55 ..    2308    2361 ..    2307    2365 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 6.3
  PP-binding   10 vlgvpleeidpdtdlfdlGlDSll 33  
                  ++ ++l  ++ +t l   G+DS++
  EEA22389.1 1490 QFSIELAGMGYTTKLHTWGIDSIS 1513
                  566777778889999999****95 PP

  == domain 2  score: 23.1 bits;  conditional E-value: 5.8e-08
  PP-binding    2 klrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlf 55  
                  +l++ va+ l++ ++eid + +l ++G+DSl+a+e++++  +e++ ++++ d++
  EEA22389.1 2308 ALIQRVAKMLQTQTSEIDTSRPLHSYGIDSLVAIEVVNWAFKELKATLTVFDIM 2361
                  578889999999**************************9999999998887766 PP

>> Thiolase_N  Thiolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   1.2e-06    0.0015      77     113 ..     171     207 ..     163     215 .. 0.91

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 1.2e-06
                 EEEEEEHGGGHHHHHHHHHHHHHHTTSHSEEEEEEEE CS
  Thiolase_N  77 pavtvnkvcsSglkavalaaqsiaageadvvvagGvE 113
                 p+  v+ +csS+l a++la+qs+ + e+d++++gG  
  EEA22389.1 171 PSFCVDTACSSSLVALHLACQSLHTRESDIAIVGGSN 207
                 56789******************************75 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.0     0.027        32      75     123 ..    1385    1433 ..    1343    1440 .. 0.81
   2 ?    7.0   0.0    0.0049       5.9      11      66 ..    2011    2069 ..    2003    2080 .. 0.81

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.027
                    T-SEEEE-SSSSS-SB-HHHHHCCHHH.S..EEEEE--SS-SB-TTGGG CS
  Shikimate_DH   75 eadvvisataseepilekeeveealkkrkkplllvDiavPRdvepevae 123 
                    ++d++i++t++ +   + e+v+ +lk+  k  ll D+ + R +e+++++
    EEA22389.1 1385 RSDIIIASTMTVTSPQTDEKVKPLLKPGGKLCLLGDVKNTRTIEERLHS 1433
                    68***********************9976888************98765 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0049
                    TT-EEEEES-SHHHHHHHHHHHCCT-CEEEEEESSHHH...HHHHHHHHT.ET-EEEEG CS
  Shikimate_DH   11 kekkvlliGaGemaelvakhLlakgvkkvvvaNRtler...akelaeelkgeeiealkl 66  
                    + + vl+ G G +++ +a+ L+++g++k++ + R+ ++   a++l +el++  ++al+l
    EEA22389.1 2011 NASYVLVGGLGGLGRSLASLLVENGARKLCFLSRSGAKtleAQRLMQELSASGVQALAL 2069
                    567789999*************************9987444677888887776666655 PP

>> PH_17  PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.1   0.00027      0.32      11      45 ..    2038    2072 ..    2036    2078 .. 0.92

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00027
       PH_17   11 klcyvaralkssdpenrllEihSpDgrealiLRck 45  
                  klc+++r+ +++  ++rl+   S++g +al+L c 
  EEA22389.1 2038 KLCFLSRSGAKTLEAQRLMQELSASGVQALALECD 2072
                  9*********9999****9999**********995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2388 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       451  (0.0251548); expected 358.6 (0.02)
Passed bias filter:                      408  (0.0227564); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 1.11u 0.33s 00:00:01.44 Elapsed: 00:00:00.52
# Mc/sec: 13828.19
//
Query:       EEA22390.1  [L=410]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.4e-18   67.1   0.0    3.8e-18   66.4   0.0    1.3  1  Thioesterase   Thioesterase domain
    7.6e-07   29.4   0.1    1.3e-06   28.7   0.1    1.4  1  PP-binding     Phosphopantetheine attachment site
    7.6e-05   23.4   0.1    0.00012   22.7   0.1    1.4  1  Abhydrolase_6  Alpha/beta hydrolase family
  ------ inclusion threshold ------
       0.13   12.1   0.0       0.21   11.4   0.0    1.2  1  Abhydrolase_3  alpha/beta hydrolase fold


Domain annotation for each model (and alignments):
>> Thioesterase  Thioesterase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.4   0.0   8.6e-22   3.8e-18       2     217 ..     127     361 ..     126     373 .. 0.81

  Alignments for each domain:
  == domain 1  score: 66.4 bits;  conditional E-value: 8.6e-22
                   EEEEE--TTCCSGGGHHHHHHCTTCEEEEEEECSTTST....SHHHCTTCHHHHHHHHHHHHHHH-SSSSEEEEEETHHHHHHHHHHHHHHHCT-SE CS
  Thioesterase   2 pLflfppagGsasvfrslasklsdpvvevlavqlpgre....rdepplesieelaaeyaealrqiqpegPyalfGhSlGgllAfevArqLesqGlav 94 
                   ++fl+p++ G   +++++    ++  + ++++  p  +     +  +++s+e la+  + a+r++q +gPy l+G+S+Gg+ AfevA+qL  qG  v
    EEA22390.1 127 TIFLLPDGSGTGMAYARIPLLGPE--ICLYGLNSPFLSslegATAWFNCSLEYLAQLWIPAIRSVQHRGPYILGGWSAGGYYAFEVAKQLIYQGDMV 221
                   688999999999999998866666..3444444443333444778899************************************************* PP

                   EEEEEESCCCCCCHHCHHCCCHTTHHTHHHHHCCTTHHHCCTTTHCCHHHHHHHHHHHHHHHHHTCCS-TTSCSE........HHCEEEEEEGSS-C CS
  Thioesterase  95 kslflidssapseteaqeasrraedeefveeltdlggtepeelledeellsellpalradyraleqyslrpeaaq........klratlfngsddkl 183
                     l+lids+ + + ea  ++    +  ++ ++   gg+     +  +e+l  +++a+   + +++ ++l ++a+         ++   ++ +   + 
    EEA22390.1 222 SKLVLIDSPCRLIFEALPMEVVSYLS-SRNLMGNWGGS----NRGTPEWLIKHFDATIKSVGNYTPTPLESSAQTnmpevyilWATDGVLTDGGVER 313
                   *************6666666666666.*********98....888899*******************977777767778888866666666666666 PP

                   TCCCCCCCHCH.............CHCTCESCEE.EEEESSHCCHHHS CS
  Thioesterase 184 kdldtlelaer.............weqktsgevs.vhvlegdhfylle 217
                    +ld+    +r             we+  +g    + +++g+hf+++ 
    EEA22390.1 314 SGLDMSVKVTRflldrppdfgplgWEELFPGMRLkIARIPGNHFTIVH 361
                   666654444448899999999999*****996444**********997 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.7   0.1   2.8e-10   1.3e-06       3      67 .]      10      74 ..       8      74 .. 0.95

  Alignments for each domain:
  == domain 1  score: 28.7 bits;  conditional E-value: 2.8e-10
  PP-binding  3 lrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaayl 67
                ++e++ + +gv+++e+  d  + dlGlD +l+  ++ ++ e   v + + ++ +++t+++l ++l
  EEA22390.1 10 VLEIIVSETGVSPDELYNDVYFADLGLDDILSKLIIDRIAEVTAVNLGPNVFQTCDTVGSLKQHL 74
                89**************9999999*****************************88*******9997 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   0.1   2.8e-08   0.00012      62     181 ..     183     304 ..     111     361 .. 0.71

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 2.8e-08
                    .........TTSEEEEEETCHHHHHHHHHHCC.......EE.EEES-..----TTTS----TTHHHHHHTT-CCCCHCCHS-HSCCCCHHHCCCCH CS
  Abhydrolase_6  62 a.......gggpvvlvGHSlGGalalaaapla.....lvvg.vlldppptalpagllaaalelllallallrllawlsreplprlfladedadaaw 144
                             +gp +l G+S GG++a ++a+++      v++ vl+d+    +++ + a ++e++  l ++     w   +  ++++l       ++
     EEA22390.1 183 IpairsvqHRGPYILGGWSAGGYYAFEVAKQLiyqgdMVSKlVLIDS---PCRLIFEALPMEVVSYLSSRNLMGNWGGSNRGTPEWLI-----KHF 270
                    2333445467777**************666669999644449*****...99999999999999999998888888855445556666.....777 PP

                    CHCCCGHHHHCCHHCHTTCCHHTT-TTGCEEECTT-C CS
  Abhydrolase_6 145 rarlarlaallaglgllpaaawadlpvpllvlggeDp 181
                     a+   +  +++ + + +  a + +p+ + +l+++D 
     EEA22390.1 271 DATIKSVGNYTPTPLESS--AQTNMPEVY-ILWATDG 304
                    777777777777777555..888888888.5576665 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   4.7e-05      0.21      72     183 ..     194     310 ..     169     316 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 4.7e-05
                    EEEEEEETHHHHHHHHHHHHHHHTT---EEEEEEE.SE....-SSTSSTTSHHHHHCHHT.TTSSSSCHHHHHHHHHHHSS.GGGGGSTTTSGGGC CS
  Abhydrolase_3  72 rivlaGdSaGGnlaaavalrardegepkvagqvli.yP....vtdlertesesikkaeel.adgplltraaldlfwrlylp.eadrddplasplla 160
                      +l+G SaGG  a  va ++  +g  +v+ +vli +P     + l + e  s+ ++++l  +    +r + +++++++ +  +++ + +  pl +
     EEA22390.1 194 PYILGGWSAGGYYAFEVAKQLIYQGD-MVSKLVLIdSPcrliFEAL-PMEVVSYLSSRNLmGNWGGSNRGTPEWLIKHFDAtIKSVGNYTPTPLES 287
                    5689**************99999865.5666666526787764444.677778877766666666678999*******996688888999999988 PP

                    S-SST---EEEEEETT-TTHHHH CS
  Abhydrolase_3 161 edlsglpptlvvvaefDplrdeg 183
                    +  +++p+++++ a+  +l d g
     EEA22390.1 288 SAQTNMPEVYILWATDGVLTDGG 310
                    77888**********99999976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (410 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.48
# Mc/sec: 2593.05
//
Query:       EEA22391.1  [L=437]
Description: O-methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-18   67.3   0.0    1.5e-18   66.9   0.0    1.2  1  Methyltransf_2   O-methyltransferase domain
    0.00093   19.9   0.0     0.0021   18.7   0.0    1.6  1  Methyltransf_12  Methyltransferase domain
    0.00094   19.8   0.0      0.002   18.8   0.0    1.6  1  Methyltransf_25  Methyltransferase domain


Domain annotation for each model (and alignments):
>> Methyltransf_2  O-methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.9   0.0   2.5e-22   1.5e-18      15     207 ..     200     410 ..     179     413 .. 0.81

  Alignments for each domain:
  == domain 1  score: 66.9 bits;  conditional E-value: 2.5e-22
                     ..HHHHH.S--..HHHHHTSSHHHH...HHHHHHHHTTHHHHHHHHHHSS-GGG-..SEEEEET-TTSHHHHHHHHH-TT-EEEEEE-.HHHHHH CS
  Methyltransf_2  15 iifkkaf.Gis..lfeaikrdeeer...akfnkglqessslvakkvleafdlegl..kslvDvGGGtGalakaivsayPtikvivfDl.peVvea 100
                     + f+ af G +  +fe+ ++++      + f++g  ++s+   +++ e +d   +   ++vDvGG  G +  a  +a P+ + iv D+ p + ++
      EEA22391.1 200 LAFDVAFpGYQkgIFEFVQKNPVAAqhyHAFQSGKVQTSRWSQRNIAEGWDWAAVgsGTIVDVGGSLGQTCIALEHASPKAQFIVQDVhPGILQK 294
                     55666654444558888888775541115567788888999999999999966552268****************************9799**** PP

                     HHHHS---...--TTEEEEES-TTTS-----SEEEEESSGGGS-HHHHHHHHHHHHHH--TT-EEEEEE----TTS---HHHHHH......HHHH CS
  Methyltransf_2 101 Akehlsag...eeervefvgGdffkdslPeaDaillkrvlhDwsdekcvklLkrvkkalpagGkvivveavlgadpsgeletelv......dlim 186
                      ++ ++ag   ++ r ++ + dff  +  ++D++++ ++ hDw d +  klLk+    l++g +++v+e vl+ +p +  +t         dl+m
      EEA22391.1 295 GRQAMEAGhpeLAARTSWEEYDFFTPQKTSGDVYIFRHIFHDWPDSDAIKLLKNQAAGLKDGAHLLVIEGVLPMAPIKRDNTIDGkniwfeDLFM 389
                     ****976522168899********99999******************************************99988665554332355899**** PP

                     HHCSS-----HHHHHHHHHHC CS
  Methyltransf_2 187 lvqteGkeRteaeyeellsea 207
                     +  ++  eRt + y +++ +a
      EEA22391.1 390 MTVHGSGERTLERYLDIFRQA 410
                     **99999****9999998876 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   3.6e-07    0.0021       1      99 []     260     359 ..     260     359 .. 0.94

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 3.6e-07
  Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvelealdlldldggssfDlvvasnvlhhl..kdirevldnirkl 92 
                      +++G+  G++  al+ + p +++++ D++p  +++ ++ + + +++ +++  +e+ d +  + + s D+ +  + +h +   d  ++l+n ++ 
       EEA22391.1 260 VDVGGSLGQTCIALEHASPKAQFIVQDVHPGILQKGRQAMEAGHPELAARTSWEEYDFFTPQ-KTSGDVYIFRHIFHDWpdSDAIKLLKNQAAG 352
                      59*******************************************************77555.56**************888888********* PP

  Methyltransf_12  93 LkpgGrl 99 
                      Lk+g++l
       EEA22391.1 353 LKDGAHL 359
                      ***9986 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.0   3.3e-07     0.002       1      96 [.     259     356 ..     259     356 .. 0.82

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 3.3e-07
                      EEEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHHTTT....TEEEEESBCCGBSSSTTTEEEEEEESTGGGSSHHHHHHHHHHHH CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlgkakvtgvDiseemleaareraeeegl....nvefvqgdaedlpfedgsfDlvvssgalhhlsdedlekalkeia 90 
                      ++d+G   G++++al ++ +ka+++  D+ ++ l++ r+ +e+ ++    + ++++ d+  +  ++ s D+ + ++ +h ++d+d+ k+lk+ a
       EEA22391.1 259 IVDVGGSLGQTCIALEHASPKAQFIVQDVHPGILQKGRQAMEAGHPelaaRTSWEEYDF--FTPQKTSGDVYIFRHIFHDWPDSDAIKLLKNQA 350
                      89**************99889********************886665544555555555..4446678999999655888************99 PP

                      HHEEEE CS
  Methyltransf_25  91 rvLkpg 96 
                        Lk+g
       EEA22391.1 351 AGLKDG 356
                      999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (437 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       355  (0.0198003); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.23s 00:00:00.71 Elapsed: 00:00:00.40
# Mc/sec: 3318.02
//
Query:       EEA22392.1  [L=226]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.4e-29  101.1   0.0    7.2e-29  100.9   0.0    1.0  1  DSBA      DSBA-like thioredoxin domain


Domain annotation for each model (and alignments):
>> DSBA  DSBA-like thioredoxin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.9   0.0     4e-33   7.2e-29       2     189 ..       6     211 ..       5     215 .. 0.94

  Alignments for each domain:
  == domain 1  score: 100.9 bits;  conditional E-value: 4e-33
                 EEEEEBTTBHHHHHHHHHHHHHHHHC........CTEEEEEEE-SSSCHHHHCT.S.GGG.........SHHHHHHHHHHHHHHHHHHT....GGSSHH CS
        DSBA   2 vdeffDvlCPyCylgkerleklaars........pdvkvvlrpfelagakkasgnvgpse.........lpeklkylledlkrlaeaegiplrfpkdkl 83 
                 + + +D +CP+Cy+g ++l ++++ +        + ++v + p+ l ++ +  g++g ++          pe+ k+++++l++++++ gi+++f +   
  EEA22392.1   6 ITVTSDTICPWCYVGRKQLIAAETLYhelhpssgDTFSVNYMPYMLLPDWP-RGPAGAQDkqeayiqrfGPERVKMMHQRLRVVGKETGIDFKFGGRT- 102
                 66779****************************666*************77.56666665678********************************997. PP

                 HHHHHHHHHHHHHHHHH..GHHHHHHHHHHHHHTSSS-TSSHHHHHHHHHHTTS..HHHHHHHHTSHHHHHHHHHHHHHHHHTT-SSSSEEEETTCEEE CS
        DSBA  84 knstraarlllaagaeg..laekvvrelfealwsegqaitddqellevaekaGl.daeeldealeseavkeavrentaaaqslgvtGvPtvvvdgkrmv 179
                 +n+++ +rl+ +a++       k   elf+ ++++  +itd ++l+++a+ +G+ da+  ++ ++s++ +++v++     q  gv+ vP ++v+gk+++
  EEA22392.1 103 GNTRDSHRLVWLAKKYSpeIESKTIDELFKSYFEKEGDITDLETLRAIASTVGIpDADFQKAIVDSDECGKEVDRAILHVQMKGVSSVPNYLVQGKYQL 201
                 7***************9988899*******************************9999999999*********************************** PP

                 ESSSSHHHHH CS
        DSBA 180 fGadrldtla 189
                  Ga +++t+ 
  EEA22392.1 202 DGARDPKTFV 211
                 ******9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (226 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       376  (0.0209716); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.32s 00:00:00.81 Elapsed: 00:00:00.49
# Mc/sec: 1380.96
//
Query:       EEA22393.1  [L=424]
Description: monoxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.1e-20   73.3   1.1    2.5e-19   69.7   1.1    2.6  1  FAD_binding_3   FAD binding domain
    4.4e-10   39.6   1.8    2.3e-09   37.3   1.4    2.3  2  NAD_binding_8   NAD(P)-binding Rossmann-like domain
      5e-06   26.0   1.1     0.0004   19.7   0.2    2.5  3  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    0.00032   19.9   4.0     0.0007   18.8   4.0    1.6  1  FAD_binding_2   FAD binding domain
    0.00049   19.8   3.5    0.00069   19.3   3.3    1.5  1  DAO             FAD dependent oxidoreductase
    0.00093   19.7   1.7     0.0019   18.7   0.8    2.0  2  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
     0.0018   17.4   3.2     0.0024   17.0   3.2    1.3  1  GIDA            Glucose inhibited division protein A
     0.0062   15.9   1.1       0.01   15.3   1.1    1.3  1  FAD_oxidored    FAD dependent oxidoreductase
     0.0078   15.0   2.1      0.013   14.3   2.1    1.3  1  HI0933_like     HI0933-like protein
  ------ inclusion threshold ------
       0.01   14.7   1.2      0.061   12.2   0.5    2.1  2  Trp_halogenase  Tryptophan halogenase
      0.022   14.0   1.1      0.044   13.0   1.1    1.5  1  Thi4            Thi4 family
      0.026   13.8   1.8      0.061   12.6   1.8    1.6  1  AlaDh_PNT_C     Alanine dehydrogenase/PNT, C-terminal domain
      0.057   12.7   0.3       0.29   10.4   0.1    2.1  2  Amino_oxidase   Flavin containing amine oxidoreductase
       0.12   11.5   1.5       0.21   10.8   1.5    1.3  1  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.7   1.1     2e-22   2.5e-19       3     344 ..       4     362 ..       2     365 .. 0.65

  Alignments for each domain:
  == domain 1  score: 69.7 bits;  conditional E-value: 2e-22
                    EEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSSS--EEEHHHHHHHHHTT-HHHHHHHSEECCCCEEEEEEECCCCCEEEEEHH..CHHCS CS
  FAD_binding_3   3 dVlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlpradglnqrtmellrqlGledrilaegapnelmgealynelsdtpkaradle..lessp 96 
                    +V++VGaG  Gl++a  L++aG +v + ek +   + + a  + +   ++l  lG   + ++  + +   +++ +++  +   +++dl+  ++  +
     EEA22393.1   4 KVIVVGAGIGGLTSAAALRRAGCDVQIFEKSAFIGQIGAALSIASNGARVLSRLGFSYSRASACTISTW-ETLSGQT-ME-VLRSVDLSssEKMFG 96 
                    7*******************************************************9988877755554.3333333.11.233444443233333 PP

                    T-CEE--HHHHHHHHHHHHHHHTEEETCSEEEECCEECCCCCCCEEE...ECCTTEEEEEEEEEEEE--GTT-HHHHHHTGG.EEEEEEEEEEEEE CS
  FAD_binding_3  97 ervtvypqteleriLvehaeerglqvrfktevesleqdeegvtaevr...dketgeeetvrakYlvGaDGgrStvrktlgie.fegeetvyeagvl 188
                    e   ++   +l + L+  a++   +++ +  v+ l+   e v+a+       ++g +   +a+ ++GaDG rS++r+ +  + ++ +++   +  +
     EEA22393.1  97 EPARTVHRVDLHNELLRIATNP--DIEGGSPVK-LHLSSEVVAATSDgtiTLRDGSI--YSADVVIGADGLRSAIRDVVLSDkIPPQSGHAGLAAF 187
                    3444444444444444443332..233333333.22222222222222223446666..69****************9887767777777566666 PP

                    EEEEEC.-SCCCTTC............CEEEEECCTTEE.............EEEECCETEEEEEEEEECCE-GGGSCCCHHHHHHHHHHHHHHTT CS
  FAD_binding_3 189 dvlfda.dlsdivep............lvlilsaesrgv.............mviPlentlerfyvqvearaekeersekfteeevkarlreivge 258
                      l+d+ +l+  +ep                       v             m  P + + ++  v +  ++++++++ +  ++ ++ r+++++  
     EEA22393.1 188 RFLVDSeELN--MEPslkpllvkhqgrA----------VaimdttrteehhiMWYPCRGGTVQNFVGIHPSKTQQTWDGEGGDRLATLRIPTSFVN 271
                    6666665555..4446754444445551..........33555555555555*******5555556666666788888888888888888888776 PP

                    SSCEE..EEEEEEEEEEEE....EEESSSEETTEEE-GGGTEEE-STTSHHHHHHHHHHHHHHHHHHHHHTTSS-GGGGHHHHHHHHHHHHH CS
  FAD_binding_3 259 ktldv..eieevsawtvaq....rvaekyrkgrvflaGDAaHihpPtgGqGlNtaiqDavnLawkLaavlkGeAkeelLdtYeeerravaqa 344
                      ++   + + + +++ +         ++ +grv l+GDAaH + P gGqG+N+ai+Da  L+  +    + +  e++L  +e+ r ++a +
     EEA22393.1 272 CLTEGfeNYRLADHVKCWPlfipDPYPTWVRGRVVLIGDAAHPMLPFGGQGSNMAIEDAGALGVLFNGIET-SQVEDRLALFEKIRYNRASR 362
                    555543233333333333310013356799********************************988777777.77777777777777777665 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.3   1.4   1.8e-12   2.3e-09       1      51 [.       7      61 ..       7      71 .. 0.87
   2 ?   -0.7   0.0       1.3   1.7e+03       4      17 ..     179     192 ..     179     221 .. 0.72

  Alignments for each domain:
  == domain 1  score: 37.3 bits;  conditional E-value: 1.8e-12
                   EE--SHHHHHHHHHHHCCTEEEEEE-SSSSSS..GGG-EECETT..CEECTS--- CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekrdrlG..Graasyevpg..vrvdygahi 51
                   +vGaG++Gl+ A++L++ag+dv+++ek+  +G  G a s+  +g  v   +g ++
     EEA22393.1  7 VVGAGIGGLTSAAALRRAGCDVQIFEKSAFIGqiGAALSIASNGarVLSRLGFSY 61
                   8***************************************999964433466666 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 1.3
                    -SHHHHHHHHHHHC CS
  NAD_binding_8   4 aGlsGlvaAylLak 17 
                    +G +Gl+a ++L +
     EEA22393.1 179 SGHAGLAAFRFLVD 192
                    69999999888864 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.2   3.1e-07    0.0004       2      34 ..       4      35 ..       3      81 .. 0.88
   2 ?    4.5   0.0     0.014        17     198     240 ..     126     165 ..     123     174 .. 0.92
   3 ?   -3.4   0.0       3.4   4.3e+03       8      21 ..     179     192 ..     179     198 .. 0.84

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 3.1e-07
                 SEEEE--SHHHHHHHHHHHHHTS-EEEEETTHC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  2 dvvviGgGpAGlaaaltlaqagakvtlvelegt 34
                 +v+v+G+G++Gl+ a  l++ag++v ++ ++ +
   EEA22393.1  4 KVIVVGAGIGGLTSAAALRRAGCDVQIF-EKSA 35
                 79*************************9.4443 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.014
                  EEEEESCEEEEEEETTEEEEEEETTSCEEEESEEEE-S-EEES CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 198 vevklgtsvkeidgngeklevvledgeeidadlvvvavGvrps 240
                  v+++l ++v++++++g+    +l dg+ + ad v+ a G+r  
   EEA22393.1 126 VKLHLSSEVVAATSDGT---ITLRDGSIYSADVVIGADGLRSA 165
                  8999************8...99*****************9976 PP

  == domain 3  score: -3.4 bits;  conditional E-value: 3.4
                  -SHHHHHHHHHHHH CS
                  xxxxxxxxxxxxxx RF
  Pyr_redox_2   8 gGpAGlaaaltlaq 21 
                  +G+AGlaa ++l  
   EEA22393.1 179 SGHAGLAAFRFLVD 192
                  79******999876 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   4.0   5.5e-07    0.0007       2      35 ..       5      38 ..       4      56 .. 0.84

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 5.5e-07
                   EEEE--SHHHHHHHHHHHHTTT-EEEEESSSGGG CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGlkvavvekeqefg 35
                   viV+G+G++GL++A+++++aG +v + ek    g
     EEA22393.1  5 VIVVGAGIGGLTSAAALRRAGCDVQIFEKSAFIG 38
                   9****************************98644 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   3.3   5.4e-07   0.00069       1      43 [.       4      46 ..       4     156 .. 0.81

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 5.4e-07
                EEEEECTSHHHHHHHHHHHHTT..EEEEESSSSTTSSGGGSSEEE CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..VtllekgdiagsgaSgrnsgl 43
                +v+++G+Gi Gl+ A +L r+g  V ++ek+ ++g  + g++  +
  EEA22393.1  4 KVIVVGAGIGGLTSAAALRRAGcdVQIFEKSAFIG--QIGAALSI 46
                59****************8889*********6666..55555444 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.8   1.5e-06    0.0019       1      35 [.       4      38 ..       4      47 .. 0.90
   2 ?   -2.8   0.0       7.7   9.9e+03      55      79 ..     126     146 ..     126     148 .. 0.75

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 1.5e-06
                EEEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSS CS
   Pyr_redox  1 kvvvvGgGyiglElAgalaelgkkVtvversdkll 35
                kv+vvG+G  gl  A+al++ g++V+++e s  + 
  EEA22393.1  4 KVIVVGAGIGGLTSAAALRRAGCDVQIFEKSAFIG 38
                79***************************987665 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 7.7
                 EEEECSEEEEEEEEETTSEEEEEEE CS
   Pyr_redox  55 ievllntkveeiegsedgvesvklk 79 
                 ++++l+++v++ + ++     ++l+
  EEA22393.1 126 VKLHLSSEVVAATSDGT----ITLR 146
                 78999999999996665....6665 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   3.2   1.9e-06    0.0024       1      52 [.       4      54 ..       4     166 .. 0.90

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 1.9e-06
                CEEEE-SSHHHHHHHHHHHHTT--EEEEES-GGGTT--SSSSEEE-TTHHHH CS
        GIDA  1 dviViGgGhAGceAAlaaarlGakvlLithkldtiaelsCnpsiggiakgll 52
                +viV+G+G  G+  A+a+ r+G++v ++ +k   i++++   si ++++  l
  EEA22393.1  4 KVIVVGAGIGGLTSAAALRRAGCDVQIF-EKSAFIGQIGAALSIASNGARVL 54
                69**************************.88888999888888888866555 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   1.1   7.8e-06      0.01       2      35 ..       5      38 ..       4      79 .. 0.95

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 7.8e-06
  FAD_oxidored  2 vvVvGGgpaGvaAAiaAaraGakvlLveergvlG 35
                  v+VvG+g++G++ A a  raG  v + e++ ++G
    EEA22393.1  5 VIVVGAGIGGLTSAAALRRAGCDVQIFEKSAFIG 38
                  9*******************************98 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   2.1   9.9e-06     0.013       2      36 ..       4      38 ..       3      51 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 9.9e-06
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SSSSS- CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVlllekakklg 36
                 +viv+G+G  Gl  A++++++g++V ++ek   +g
   EEA22393.1  4 KVIVVGAGIGGLTSAAALRRAGCDVQIFEKSAFIG 38
                 79****************************97665 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.5   4.7e-05     0.061       1      40 [.       4      41 ..       4      69 .. 0.80
   2 ?    0.7   0.0      0.14   1.8e+02     190     221 ..     143     174 ..     126     182 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 4.7e-05
                    EEEEE--SHHHHHHHHHHHHHTTTSSEEEEEE-SS.S---S CS
  Trp_halogenase  1 kivivGGGtaGwlaAaalakalkgklevtlvesee.igtvg 40
                    k+++vG+G+ G ++Aaal++a+   ++v++ e+++ ig++g
      EEA22393.1  4 KVIVVGAGIGGLTSAAALRRAG---CDVQIFEKSAfIGQIG 41
                    79********************...99**999875255555 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.14
                     EEETTS-EEE-SEEEE-SGGG-IIIIIIT--- CS
  Trp_halogenase 190 lrledgreveadlfiDcsGfrgllieqaLktg 221
                     ++l dg  ++ad +i + G r+ + + +L+ +
      EEA22393.1 143 ITLRDGSIYSADVVIGADGLRSAIRDVVLSDK 174
                     57899*****************9998888765 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   1.1   3.4e-05     0.044      19      54 ..       4      38 ..       1      52 [. 0.90

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 3.4e-05
                EEEEE--SHHHHHHHHHHHHCTTS-EEEEESSSS-- CS
        Thi4 19 DvvivGaGssGLtaayylakkpdlkvailersvspG 54
                 v++vGaG  GLt+a  l ++ +  v i+e+s  +G
  EEA22393.1  4 KVIVVGAGIGGLTSAAALRRA-GCDVQIFEKSAFIG 38
                69*****************99.9*******997766 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   1.8   4.8e-05     0.061      30      60 ..       4      34 ..       2      42 .. 0.94

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 4.8e-05
                 EEEEESTSHHHHHHHHHHHHTT-EEEEEESS CS
  AlaDh_PNT_C 30 kvlviGgGvaGlqAiatakglgakVtvlDvr 60
                 kv+v+G+G+ Gl ++a+ ++ g +V++++++
   EEA22393.1  4 KVIVVGAGIGGLTSAAALRRAGCDVQIFEKS 34
                 8**************************9976 PP

>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.1   0.00022      0.29       1      27 [.      12      38 ..      12      39 .. 0.95
   2 ?   -0.8   0.0      0.56   7.2e+02     223     257 ..     126     157 ..     115     165 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00022
                   HHHHHHHHHHHHTTEEEEEEESSSSSB CS
  Amino_oxidase  1 laGLaaArqLlsaGfdVtvlEardrvG 27
                   + GL+ A  L +aG dV+++E +  +G
     EEA22393.1 12 IGGLTSAAALRRAGCDVQIFEKSAFIG 38
                   68********************99888 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.56
                    EEEETSEEEEEEEEETTCEEEEETTSTEEEESEEE CS
  Amino_oxidase 223 ldirlntrVkeikregdgvtvtledgevveaDaVv 257
                    ++++l+++V   +      t+tl+dg+ ++aD V+
     EEA22393.1 126 VKLHLSSEVVAATS---DGTITLRDGSIYSADVVI 157
                    55666655555554...3477788*********99 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   1.5   0.00016      0.21       1      31 [.       6      35 ..       6      45 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00016
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEkgn 31
                 i++GaG  Gl++a +l++ag  d+ i Ek +
   EEA22393.1  6 IVVGAGIGGLTSAAALRRAGC-DVQIFEKSA 35
                 89*******************.8******85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (424 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       498  (0.0277762); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.64u 0.29s 00:00:00.93 Elapsed: 00:00:00.47
# Mc/sec: 2719.76
//
Query:       EEA22394.1  [L=2039]
Description: polyketide synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.4e-71  240.3   0.1    4.5e-71  239.4   0.1    1.4  1  ketoacyl-synt    Beta-ketoacyl synthase, N-terminal domain
      1e-50  172.7   0.0      3e-50  171.2   0.0    1.8  1  SAT              Starter unit:ACP transacylase in aflatoxin b
    5.9e-34  118.0   0.0      1e-33  117.2   0.0    1.4  1  Acyl_transf_1    Acyl transferase domain
    3.4e-33  114.2   0.1      1e-32  112.6   0.0    1.9  2  Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
    3.6e-16   59.3   0.2    9.5e-16   57.9   0.1    1.7  2  PS-DH            Polyketide synthase dehydratase
    7.8e-11   42.2   0.3    2.4e-10   40.6   0.3    2.0  1  PP-binding       Phosphopantetheine attachment site
    3.9e-08   33.7   0.0    1.1e-07   32.3   0.0    1.8  1  Thioesterase     Thioesterase domain
     0.0013   19.2   1.0     0.0042   17.5   0.0    2.5  3  KAsynt_C_assoc   Ketoacyl-synthetase C-terminal extension
  ------ inclusion threshold ------
      0.047   13.5   0.4        3.7    7.5   0.1    2.7  2  ANTAR            ANTAR domain
       0.08   12.3   1.3       0.16   11.3   1.3    1.4  1  Thiolase_N       Thiolase, N-terminal domain


Domain annotation for each model (and alignments):
>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  239.4   0.1   2.5e-74   4.5e-71       3     253 .]     380     628 ..     379     628 .. 0.96

  Alignments for each domain:
  == domain 1  score: 239.4 bits;  conditional E-value: 2.5e-74
                    -EEEEEEEEEBTTBSSHHHHHHHHHTT---EEES-TTSSCGTTSBTSSTTEEE-BSS.EEE..S.TTEGGTTSTHHHHHHHCTS-HHHHHHHHHHH CS
  ketoacyl-synt   3 pvaivGmgarfPggndveefwelLlegrdaiselpadrwdadklydpparaagkiktklggfld.vddfdpeffgispreaeamdpqqrllleaaw 97 
                    +vaivGm++rfPg+++v+ fw+ +l gr++i+++p++r+d +++ydp+ + ++ +++ +g+fld    fd+++f++sprea++mdp+ rl+l++a+
     EEA22394.1 380 RVAIVGMAGRFPGSDTVDGFWDDVLMGRSHIEKVPKSRFDLNDFYDPTGQQKNSTTAIHGAFLDdPGLFDHRLFNVSPREAAQMDPMVRLALTTAY 475
                    7*********************************************************************************************** PP

                    HHHHHHTS-HHTC...TTGGEEEEEEESSTHHHHHHHHHHHTTGGGSCTTHHHHHSTTHHHHHHHHHHT--SSEEEEESGGGHHHHHHHHHHHHHH CS
  ketoacyl-synt  98 ealedagltpeel...dgsrvgvfiGvgagdyaalaaldedgsevkaspkavgavlanviagrisyalglrGpsvtvdtACsSslvavhaavqslr 190
                    eal++ag++p ++   +++r++ f+G + +d+++  +l+++g   +++   +++v +++ ++r++y++++ G s+++d+AC+Ss +a+ +a++sl 
     EEA22394.1 476 EALQSAGYSPGATpatQTNRIATFLGQTGEDWHE--VLNNQG--IDIYY--IPSVCRAFGPSRLNYHFKFGGGSYAMDSACASSTTAISLACSSLI 565
                    **********9995544555**********9965..888777..78888..77789**************************************** PP

                    TTS-SEEEEEEEE---SHHHHHHHHHTTBB-TTSGGGTTBTTB-SB-BB-EEEEEEEEECHHH CS
  ketoacyl-synt 191 sgeadvalaGGvellltpeavagfsaagllspdgrckafdpkadGfvlGEGvGavvLkrleda 253
                    ++e+d+a+aGG ++l++p+++ g+s+ag+lsp++ c+++ ++adG+ +GEGv+++vLkrleda
     EEA22394.1 566 ARECDTAVAGGGSVLVSPNSFSGLSKAGMLSPTNGCRTYHDDADGYARGEGVAMIVLKRLEDA 628
                    *************************************************************98 PP

>> SAT  Starter unit:ACP transacylase in aflatoxin biosynthesis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  171.2   0.0   1.7e-53     3e-50       1     230 [.      12     242 ..      12     252 .. 0.96

  Alignments for each domain:
  == domain 1  score: 171.2 bits;  conditional E-value: 1.7e-53
         SAT   1 llFGDqtadvlpeLrkLl.qakenplLrsFLekasealraeisrlpaaerkslprftslqeller.ysesglkspalssallciaqlaqfivyleenpe 97 
                 llFGDqt++ l+++++L+ +ak++p+ ++FL++a+++l+ eis+++++e     +f++l  l+e+  +++g ++ ++ ++l+ci +l+++i  +e++p 
  EEA22394.1  12 LLFGDQTVEKLSSIQALVrNAKSSPATKRFLQEATDVLQLEISKISRTEHGWAGNFDTLLGLAEEnADQDGNANMIVATMLMCIGRLGSLIFLAEKDPA 110
                 79*************************************************************99788899999************************* PP

         SAT  98 eyps.pestylvGlCtGllaAaavacskslseLvplaveavrvafrlGlevarvaarleegsssssesWslavtglseeelekalaefneekglppasr 195
                  + + +++  ++++CtGll+A++v ++k++s+L  l++e++ ++frl+l+  r+ ++l   + + +++W+ ++tgl e++++k+l+ef++++++p+ ++
  EEA22394.1 111 ILGTsENPVNVLAFCTGLLPASLVVAAKDTSDLFTLSREIISITFRLALQGRRRMQMLG--TGNLNGTWARTYTGLLEDKANKILDEFHQSQKTPTPRK 207
                 ****78899**************************************************..77888********************************* PP

         SAT 196 vyisavssssvtisGpPstleallksskakkkkkk 230
                 + i+avs+s+vt+ GpP +l++l ++sk   ++++
  EEA22394.1 208 IAIGAVSTSWVTLFGPPGSLDRLHNWSKELGSLPH 242
                 ************************99998877665 PP

>> Acyl_transf_1  Acyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.2   0.0   5.7e-37     1e-33       2     317 ..     915    1246 ..     914    1248 .. 0.82

  Alignments for each domain:
  == domain 1  score: 117.2 bits;  conditional E-value: 5.7e-37
                     EEE--TT---TTTTCCHHHC-HHHHHHHHHHHHHCCHHHT-.-HHHHHHS--TTGGGSHHH......HHHHHHHHHHHHHHHHHHTT-TTSEEE CS
  Acyl_transf_1    2 fvfsGqGsQwaGMGmeLlktskafaaviaradeafksqygf.svldvlrnnpeglldaiqf......vqpaLaavqialaellkskGvrpaavv 88  
                     ++f+GqGsQ a MG++L++t+  fa ++   ++   + +g+   + ++++++++ +++  +      +q+a +a+++ala l+ks G++ ++v+
     EEA22394.1  915 WLFTGQGSQYASMGRDLYRTNTFFASTLLDYEQTAMA-MGLpRFMGIIADEDNSDVEDLAHrwsptqIQLATVALEMALAHLFKSWGLTADLVI 1007
                     9********************************9999.66648999***999966665543222222899999********************* PP

                     E-TTHHHHHHHHCCSSSHHHHHHHHHHHHHHHHHHT..S-EECCEECS.HHHHHHH...TT.E...EEEEEECCCCECCEEHHHHHHHHHHHHH CS
  Acyl_transf_1   89 GHSlGElAaavvagalsseeallavvlrsrlmmqla..gpgdmaavelaeeeeklr.cqddvv...gavansprrvvisgsqealrelvervsk 176 
                     GHSlGE+Aa+  ag ls+ + l  v  r  lm ++    + +m+a + ++e++k    +  +v    a+ n p+ +v+sg+ e++++l  ++++
     EEA22394.1 1008 GHSLGEYAALNIAGVLSAGDVLYLVGSRANLMEKNLqlNEYAMLATGYDPETLKKSfETYGLVscdIACINAPSVTVASGKMESISALQSHLQQ 1101
                     ********************************988756677888888888888887665555523369******************99999888 PP

                     CC.......CCEEECCCEECTTCCCCCCCCHHHHHHHHCCCHHCHHTTBEHCCCHHHHHHCHHHHHHHHHHHCHCCHCCHHTTS....SSECC- CS
  Acyl_transf_1  177 eg......vgalvenvnvavhspqvdaiadalasaladiaprkpkvakisstsldesserelsaeywvanlrspvrfaeavlsa....aetipl 260 
                     +       +     +  + +hs+q++++  +       +  ++p+ + iss++   ++e+ +s  y v+  r++v f  a+  +    +   + 
     EEA22394.1 1102 QSnekgieIKTTILKTPYGFHSRQIEPVLREFGDLARGVEFNEPHTPIISSLT--GMVETGFSPTYLVRQARETVNFVTALYTMreagFVGDNT 1193
                     752212112233345679***********998776666898999999998876..589999*****************9988773335566799 PP

                     CCEECSSSSCCHCCCCCCCHHGGG-TCCCCCCTEETTSS-HHHCHHHHHHHHHHCT- CS
  Acyl_transf_1  261 vfveispHslllaalektlksaedvksatlvGklkrdltdflvtflyllakahltgs 317 
                     +f+ei p ++ l  l++tl+     +s +lv  lk+  ++  vt    l++a  tgs
     EEA22394.1 1194 TFIEIGPSPVCLGLLRRTLD---LPPSTQLVSALKPRIDN-WVTTSEVLKVAYETGS 1246
                     ********************...46888999999999999.6666666666666665 PP

>> Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.6   0.0   5.7e-36     1e-32       1     114 [.     636     750 ..     636     753 .. 0.98
   2 ?   -3.8   0.0       7.2   1.3e+04      30      75 ..    1060    1105 ..    1058    1112 .. 0.75

  Alignments for each domain:
  == domain 1  score: 112.6 bits;  conditional E-value: 5.7e-36
                      SEEEEEEEEEE--STSSSTSTTHHHHHHHHHHHHHHHT--GGGEEEEE-SS-SSHHHHHHHHHHHHHHHGGGGG.SCTSEEE-THHHH-B-GGG CS
  Ketoacyl-synt_C   1 yavikgsavnsdgahnsltapngeaqaraiekalaeagvdpedvdyveahgtgtplgDpiElealkkvfgekar.kqplavgSvKsniGHleaA 93 
                      ++vi+g+a ++++ + s+t+p++eaq+r++ ++l ++ +dp+++ yve+hgtgt++gD  E++++ +v+g++++ ++pl vg+vK+ +GH+eaA
       EEA22394.1 636 LGVIRGWARTYSDTAPSITHPSHEAQERIYSQVLHQSCLDPAEIAYVEMHGTGTQAGDLEEMTSVLNVIGQNRTrDNPLNVGAVKAVVGHGEAA 729
                      589********************************************************************99999****************** PP

                      HHHHHHHHHHHHHHHTEE--B CS
  Ketoacyl-synt_C  94 aGvaelikvvlalkhgvippt 114
                      aGv++likv++++++++ipp+
       EEA22394.1 730 AGVTSLIKVLMMMRDRKIPPQ 750
                      ********************8 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 7.2
                       HHHHHHHHT--GGGEEEEE-SS-SSHHHHHHHHHHHHHHHGGGGGS CS
  Ketoacyl-synt_C   30 iekalaeagvdpedvdyveahgtgtplgDpiElealkkvfgekark 75  
                       ++k +++ g+   d+  ++a    ++ g    ++al++ +++++++
       EEA22394.1 1060 LKKSFETYGLVSCDIACINAPSVTVASGKMESISALQSHLQQQSNE 1105
                       5677778888888889999888888888888888888888887765 PP

>> PS-DH  Polyketide synthase dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.9   0.1   5.3e-19   9.5e-16      12     296 ..    1324    1630 ..    1314    1632 .. 0.78
   2 ?   -2.6   0.0       1.4   2.5e+03      68     130 ..    1912    1971 ..    1902    1991 .. 0.72

  Alignments for each domain:
  == domain 1  score: 57.9 bits;  conditional E-value: 5.3e-19
                  -SS-EEEEEEE-.S-SS.TTTSEEETTEEB--TTHHHHHHHHHHHHTS....---....-EEEEEEEE----.B--SS-EEEEEEEEE-TTS-E... CS
       PS-DH   12 sdkevvfrnrlr.laelpwLrDHrvdgkvvlPgagylemaleAarqlt....ges...kavelrdvsilkalvlpedepvevqlslepeedgadraw 100 
                  ++  vvf+++l+ ++ l+ ++ H+v+ +++ P+ +++ +a+ A + ++    g+s     +++rd+++ +alvl +++p+ v  +    + ++   +
  EEA22394.1 1324 NKLTVVFSTDLDdTHLLQAIEGHVVNQQTICPAGVFIDIAMTATKYTHihlhGDSidvPTMTIRDFEMAHALVLTPGNPKPVLYTTSVYNTEEM--T 1418
                  566777888887677777899**********************998886665555878799*****************9988888888855544..7 PP

                  .EEEEEEE-SS-TT.EEEEEEEEEE-----...............--B--HHHHHHHS-SEE....E-HHHHHHHHHHHSEEE-GGG--EEEEEEET CS
       PS-DH  101 vefeifSregggeewtehatGtvrlaegaa...............aaavdlealqarcaepaslrsvssaefYerlaargleyGpsFqglralwrgd 182 
                  v+++ +Sr+g +++ ++h + tv+++ + a               +    +eal ++++  + +  + ++ +Y+ + +  ++y +++++l++++ ++
  EEA22394.1 1419 VTVSFHSRTGIEKD-VTHGRCTVHFDHEYAsawkisnaqtlflvkS---RMEALTEHRKSGR-AHHLLKTVVYKLF-RNVVDYSERYRALEEVTLDT 1509
                  899999*9999997.7777777777766667788877766664433...3333322222222.23355779*****.888***************97 PP

                  TEEEEEE---...GGGSSTTTT..-SB-HHHHHHHHHHG..GG.----------EEEEEE.EEEEE-S...-BTS--EEEEEE.----SS-EEEEEE CS
       PS-DH  183 gealaelrlp...eelaggesa..yvlhPallDaalQllaaal.saeaekadaaylPvai.erlrvyrpssaageelwvharl.eeegarsivadlt 271 
                  ++  a   +    ++l++++++  + ++P+ +Da++Ql + +l +  + ++d a++ v++ er+++ +  ++++++  +++ + e+++++ i++d  
  EEA22394.1 1510 QSHDAIGMVRflpNTLQDDAKPnqFCFDPYSIDAVMQLAGFVLnNGMRYEDDIACIFVGFhERCEIEK--PRSDKDYFSYVCMqEASQGSIITGDCY 1604
                  765555555555577777776688*************8777787556788888999997735666664..567999999999988889999****** PP

                  EE-.SS-BEEEEEESEEEEE--XXXX CS
       PS-DH  272 lvd.edGrvvaeieglrlrrvereal 296 
                  +++ e+Gr+    +gl++++ ++ al
  EEA22394.1 1605 VFEaESGRLTQVTTGLKFQKMKKVAL 1630
                  ***9***************9988775 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.4
                  EEEE----.B--SS-EEEEEEEEE-TTS-E....EEEEEEE-SS-TT.EEEEEEEEEE----- CS
       PS-DH   68 dvsilkalvlpedepvevqlslepeedgadrawvefeifSregggeewtehatGtvrlaegaa 130 
                   +++ + l l+e+++v++ l + p++ ++ + ++ +++  +++ ++  +eh+++ + + ++ +
  EEA22394.1 1912 AIEVVRIL-LAEGDTVDLLLLIDPADVDTIDSRLPVKLVQVASTAQ--REHMQAMANALRKYT 1971
                  56667777.8999999999999999766667777777777777775..899999998776655 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.6   0.3   1.3e-13   2.4e-10       2      62 ..    1702    1763 ..    1701    1768 .. 0.87

  Alignments for each domain:
  == domain 1  score: 40.6 bits;  conditional E-value: 1.3e-13
  PP-binding    2 klrelvaevlgvpleeidpdtdlf.dlGlDSllavellaaleeefgveiplsdlfehptlae 62  
                  +++++va+  g++  ++ +d  lf dlG+DSl+a+++l+ l+++ gv+i+   +fe+ t+++
  EEA22394.1 1702 TVLNIVATESGCSMGDLLDDNALFaDLGVDSLMALTILSLLKRHTGVDIEANFFFEYETVGD 1763
                  799*********9999744444555***********************************98 PP

>> Thioesterase  Thioesterase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.3   0.0     6e-11   1.1e-07      44     101 ..    1876    1933 ..    1833    1947 .. 0.80

  Alignments for each domain:
  == domain 1  score: 32.3 bits;  conditional E-value: 6e-11
                    CTTCHHHHHHHHHHHHHHH-SSSSEEEEEETHHHHHHHHHHHHHHHCT-SEEEEEEES CS
  Thioesterase   44 plesieelaaeyaealrqiqpegPyalfGhSlGgllAfevArqLesqGlavkslflid 101 
                    +  +i +la+ ya++lr++qp+gPy ++G S  ++lA ev r L ++G +v  l lid
    EEA22394.1 1876 ESITIPSLASIYAATLRKEQPRGPYLIAGMSSSSILAIEVVRILLAEGDTVDLLLLID 1933
                    456899***************************************************9 PP

>> KAsynt_C_assoc  Ketoacyl-synthetase C-terminal extension
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0         7   1.2e+04      72     103 ..      23      54 ..       4      57 .. 0.73
   2 !   17.5   0.0   2.3e-06    0.0042      27     105 ..     791     867 ..     758     875 .. 0.86
   3 ?   -3.9   0.0        10   1.8e+04      61      87 ..    1080    1105 ..    1078    1117 .. 0.69

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 7
  KAsynt_C_assoc  72 eaveallekleehlldaellsllneilseeis 103
                     ++++al+ ++++ ++++ +l+ + ++l+ eis
      EEA22394.1  23 SSIQALVRNAKSSPATKRFLQEATDVLQLEIS 54 
                     46778888888888888888888888887776 PP

  == domain 2  score: 17.5 bits;  conditional E-value: 2.3e-06
  KAsynt_C_assoc  27 vgvNsfGfGGsnvHviLksnkkekrkeeskeeslprLlvlsgrteeaveallekleehlldaellsllneilseeisrl 105
                       vNs   +G n+ + +++++    k+ ++  +  +++++s+rte +++++ e+l +h   +++++l + ++++  +r 
      EEA22394.1 791 LLVNSLDASGGNTSLAIEEPPASPVKNPDP--RGGHVVAISARTELSLNQNRERLLDHISRNSQVKLEDLAYTTTARRI 867
                     559******************999999988..9*********************************9999999888874 PP

  == domain 3  score: -3.9 bits;  conditional E-value: 10
  KAsynt_C_assoc   61 prLlvlsgrteeaveallekleehlld 87  
                      p++ v+sg+  e+++al ++l++++++
      EEA22394.1 1080 PSVTVASGK-MESISALQSHLQQQSNE 1105
                      566666666.67888888888887544 PP

>> ANTAR  ANTAR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0     0.042        76      33      50 ..     842     859 ..     841     861 .. 0.93
   2 ?    7.5   0.1     0.002       3.7      12      30 ..    1760    1778 ..    1757    1781 .. 0.90

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.042
                 HHHHHHHCTTTS-HHHHH CS
       ANTAR  33 rlLrklSmdsnvklrevA 50 
                 rlL   S++s+vkl+++A
  EEA22394.1 842 RLLDHISRNSQVKLEDLA 859
                 89999************9 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.002
                  HHHHHHHHHHHHHT--HHH CS
       ANTAR   12 lieqAkgiLmeryglsede 30  
                  +++ Ak++Lmeryg  ede
  EEA22394.1 1760 TVGDAKRALMERYGRREDE 1778
                  7899**********99998 PP

>> Thiolase_N  Thiolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   1.3   9.2e-05      0.16      80     112 ..     545     577 ..     542     585 .. 0.93

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 9.2e-05
                 EEEHGGGHHHHHHHHHHHHHHTTSHSEEEEEEE CS
  Thiolase_N  80 tvnkvcsSglkavalaaqsiaageadvvvagGv 112
                 +++ +c+S+ +a+ la+ s+ a e+d +vagG+
  EEA22394.1 545 AMDSACASSTTAISLACSSLIARECDTAVAGGG 577
                 6899****************************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2039 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       491  (0.0273858); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 1.03u 0.27s 00:00:01.30 Elapsed: 00:00:00.44
# Mc/sec: 13784.70
//
Query:       EEA22395.1  [L=575]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.9e-29  100.5   0.2      3e-14   52.7   0.3    2.1  2  Trp_halogenase  Tryptophan halogenase
    1.1e-08   34.7   0.1    5.4e-06   25.9   0.0    2.5  2  FAD_binding_3   FAD binding domain
    1.6e-05   25.0   0.1    7.9e-05   22.8   0.0    2.1  2  NAD_binding_8   NAD(P)-binding Rossmann-like domain
    2.8e-05   23.5   0.0    5.5e-05   22.5   0.0    1.6  1  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    4.1e-05   22.5   0.0    0.00021   20.1   0.0    2.0  2  HI0933_like     HI0933-like protein
    8.4e-05   21.8   0.0    0.00014   21.1   0.0    1.3  1  GIDA            Glucose inhibited division protein A
    0.00021   20.8   0.1    0.00032   20.2   0.1    1.2  1  FAD_oxidored    FAD dependent oxidoreductase
    0.00036   19.7   0.1    0.00071   18.8   0.1    1.4  1  FAD_binding_2   FAD binding domain
    0.00066   19.4   0.1     0.0037   16.9   0.1    2.2  2  DAO             FAD dependent oxidoreductase
     0.0024   17.2   0.0      0.031   13.5   0.0    2.1  2  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
      0.047   13.9   0.1        7.6    6.8   0.0    2.6  3  TrkA_N          TrkA-N domain
      0.049   14.2   0.0       0.13   12.8   0.0    1.8  1  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
      0.089   12.0   0.2       0.28   10.4   0.0    1.9  2  Thi4            Thi4 family
      0.095   11.7   0.0       0.15   11.1   0.0    1.3  1  Lycopene_cycl   Lycopene cyclase protein


Domain annotation for each model (and alignments):
>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.7   0.0   3.3e-15   4.2e-12       2      89 ..       9      90 ..       8     119 .. 0.78
   2 !   52.7   0.3   2.4e-17     3e-14     196     378 ..     170     380 ..     160     440 .. 0.77

  Alignments for each domain:
  == domain 1  score: 45.7 bits;  conditional E-value: 3.3e-15
                    EEEE--SHHHHHHHHHHHHHTTTSSEEEEEE-SSS---SS-EE--THHHHTHHHHT--HHHHCHHCT-EEE-EEEEESSSSCESEEEE CS
  Trp_halogenase  2 ivivGGGtaGwlaAaalakalkgklevtlveseeigtvgvGeatipsirkllrlLgideeeflreteatfKlgikFedWgkkgeryih 89
                    ++++GGG+aG+  A+ala+ +   +e  l+e+e+++++ vGe+ +ps+r+ lr+++ d +  l +  +  K g+ F + ++k+  y+ 
      EEA22395.1  9 VLVIGGGPAGSYCASALAREG---IETVLLEAEKFPRYHVGESMLPSLRHYLRFIEADKK--LDAHGFIRKNGALF-KLNSKPAAYTD 90
                    89******************9...99*****************************98876..66666666666666.33444444443 PP

  == domain 2  score: 52.7 bits;  conditional E-value: 2.4e-17
                     -EEE-SEEEE-SGGG-IIIIIIT---EEE-TTT----EEEEEEEE--H..........---SSEEEEE-SSEEEEEEEETTEEEE.EEEE-TTTS CS
  Trp_halogenase 196 reveadlfiDcsGfrgllieqaLktgfedwsdvLltdrAlavqvesee..........lvepytrataekaGWtWkiPLqhrlgn.Gyvyssaha 279
                      ++++d  +D+sG +gl+  +  k++  +  ++L   +++a+ ++ ++             py +a+a+++GWtW+iPL++   + G+v  ++ +
      EEA22395.1 170 GSIKFDYLVDASGRQGLVSTKYWKNRKMNTGAQL---QSVATWGYWTGggivekgtsrEGCPYFEAIADASGWTWYIPLHNGQWSvGVVMNQKVL 261
                     46999*****************************...8888888877777777777666779999**************9888777****99987 PP

                     .-HHHHHHHHHHHCT--TTTS-.EEEE---EE.............ES-SEETTEEE-.CCCTEE--CCCS-HHHHHHH....HHHHHHHT--BTT CS
  Trp_halogenase 280 .dddeAlaellaeldgkleaep.rkirfttGr.............rkqawvknvval.GlasgfvePlestsihliqa....alrrLlallpdks 354
                      d+ +A+ + ++ + ++ + +p  +  ++ G              +++a++   + + G+a +f++P +s+++hl+ +    a+++++a +  + 
      EEA22395.1 262 aDKKRAAGDGKNVYLQTIRETPgLQALLENGElvtelrsasdwsyNATAYSSPYLRVaGDAGCFIDPFFSSGVHLALTggfsAATTICASIKGQT 356
                     5778888888877777777777788888999899999988888887777777777656*****************98866667777777766665 PP

                     --HHHHHHHHHHHHHHHHHHHHHH CS
  Trp_halogenase 355 depaaiaefnrevarelervrdfi 378
                      e  a+    ++v++ ++r+  ++
      EEA22395.1 357 SEIGAAIWHTKKVSESYTRFLVIV 380
                     554444445555555555555555 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.9   0.0   4.2e-09   5.4e-06       1      34 [.       6      39 ..       6     134 .. 0.92
   2 !    6.3   0.0    0.0038       4.8     138     328 ..     157     358 ..     150     367 .. 0.68

  Alignments for each domain:
  == domain 1  score: 25.9 bits;  conditional E-value: 4.2e-09
                   EEEEEEE--SHHHHHHHHHHHHTTHHEEEEESSS CS
  FAD_binding_3  1 etdVlIVGaGpaGlmlallLseaGvrvvlvekrs 34
                   +t+Vl++G+GpaG   a+ L++ G+++vl+e  +
     EEA22395.1  6 KTTVLVIGGGPAGSYCASALAREGIETVLLEAEK 39
                   689***************************9765 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0038
                    CCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHHH........TGGEEEEEEEEEEEEEEEEEEC-SCCCTTC..CEEEEECCTTEEEEEECCE.T CS
  FAD_binding_3 138 vtaevrdketgeeetvrakYlvGaDGgrStvrktl........giefegeetvyeagvldvlfdadlsdivep..lvlilsaesrgvmviPlen.t 222
                    v+a   +k+tg    ++ +Ylv a G ++ v  +         g ++++  t   ++  +++ ++ +s  +e+   +  +++ s+    iPl n +
     EEA22395.1 157 VSASWVNKDTGDAGSIKFDYLVDASGRQGLVSTKYwknrkmntGAQLQSVATWGYWTGGGIV-EKGTS--REGcpYFEAIADASGWTWYIPLHNgQ 249
                    67777888888888888888888888888886554111111113333333333333333444.33333..33354455556666666888888844 PP

                    EEEEEEEEECCE-GGGSCCCHHHHHHHHHHHHHHTTSSCEE...EEEEEEEEEEEEEEESSSEETTEEE-GGGTEEE-STTSHHHHHHHHHHHHHH CS
  FAD_binding_3 223 lerfyvqvearaekeersekfteeevkarlreivgektldv...eieevsawtvaqrvaekyrkgrvflaGDAaHihpPtgGqGlNtaiqDavnLa 315
                     +  +v+ +    +++r     ++++ + +re  g ++l      ++e +++  +++ a+ y++  + +aGDA     P    G+ +a+   +  a
     EEA22395.1 250 WSVGVVMNQKVLADKKRAAGDGKNVYLQTIRETPGLQALLEngeLVTELRSASDWSYNATAYSSPYLRVAGDAGCFIDPFFSSGVHLALTGGFSAA 345
                    4444444444555555566666777788888888888776633346788888899999************************************** PP

                    HHHHHHHTTSS-G CS
  FAD_binding_3 316 wkLaavlkGeAke 328
                    + + a +kG+ +e
     EEA22395.1 346 TTICASIKGQTSE 358
                    ********99875 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8   0.0   6.1e-08   7.9e-05       1      28 [.      11      38 ..      11      42 .. 0.95
   2 ?   -1.9   0.0       3.1     4e+03      39      63 ..     351     371 ..     340     376 .. 0.66

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 6.1e-08
                   EE--SHHHHHHHHHHHCCTEEEEEE-SS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekr 28
                   ++G+G +G+++A++La++g++ +lle+ 
     EEA22395.1 11 VIGGGPAGSYCASALAREGIETVLLEAE 38
                   8************************975 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 3.1
                    CETTCEECTS---EEETTHHHHCHH CS
  NAD_binding_8  39 evpgvrvdygahifhgsgyypnvrr 63 
                    +++g++ + ga i+h+    ++v++
     EEA22395.1 351 SIKGQTSEIGAAIWHT----KKVSE 371
                    3478888999999999....45555 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5   0.0   4.3e-08   5.5e-05       2      45 ..       8      52 ..       7     186 .. 0.76

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 4.3e-08
                 SEEEE--SHHHHHHHHHHHHHTS-EEEEE...TTHCHHHCSHHHHCH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxx RF
  Pyr_redox_2  2 dvvviGgGpAGlaaaltlaqagakvtlve...legtclnggcllska 45
                  v+viGgGpAG  +a  la+ g++++l+e     ++++++ +l+   
   EEA22395.1  8 TVLVIGGGPAGSYCASALAREGIETVLLEaekFPRYHVGESMLP--S 52
                 699*************************8555555555555554..3 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   0.0   1.7e-07   0.00021       2      33 ..       8      39 ..       7      44 .. 0.93
   2 ?   -0.9   0.0      0.39     5e+02     226     246 ..     105     125 ..      73     128 .. 0.80

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 1.7e-07
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SSS CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVlllekak 33
                 +v+viGgG+AG ++A ++a++g +++lle++k
   EEA22395.1  8 TVLVIGGGPAGSYCASALAREGIETVLLEAEK 39
                 699**************************876 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.39
                  TEEEEEEEEE-SSEEESHHHH CS
  HI0933_like 226 katekgellfThrGlsGpail 246
                   +++  +llf h G sG  i+
   EEA22395.1 105 IRSQADDLLFRHAGTSGAKIF 125
                  568899***********9875 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.1   0.0   1.1e-07   0.00014       2      29 ..       9      37 ..       8      57 .. 0.87

  Alignments for each domain:
  == domain 1  score: 21.1 bits;  conditional E-value: 1.1e-07
                EEEE-SSHHHHHHHHHHHHTT--EEEE.E CS
        GIDA  2 viViGgGhAGceAAlaaarlGakvlLi.t 29
                v ViGgG AG+ +A a+ar G++++L+ +
  EEA22395.1  9 VLVIGGGPAGSYCASALAREGIETVLLeA 37
                99************************943 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.1   2.5e-07   0.00032       2      33 ..       9      40 ..       8      41 .. 0.95

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 2.5e-07
  FAD_oxidored  2 vvVvGGgpaGvaAAiaAaraGakvlLveergv 33
                  v+V+GGgpaG  +A a ar+G +++L+e +++
    EEA22395.1  9 VLVIGGGPAGSYCASALAREGIETVLLEAEKF 40
                  99**************************9875 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.1   5.5e-07   0.00071       2      33 ..       9      40 ..       8      46 .. 0.91

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 5.5e-07
                   EEEE--SHHHHHHHHHHHHTTT-EEEEESSSG CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGlkvavvekeqe 33
                   v+ViG+G AG  +A ++a++G +++++e e+ 
     EEA22395.1  9 VLVIGGGPAGSYCASALAREGIETVLLEAEKF 40
                   9***************************9875 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.1   2.9e-06    0.0037       2      32 ..       9      41 ..       8      48 .. 0.91
   2 ?   -1.8   0.0       1.4   1.8e+03     152     173 ..     113     134 ..      75     143 .. 0.84

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 2.9e-06
                EEEECTSHHHHHHHHHHHHTT..EEEEESSSST CS
         DAO  2 vviiGGGiiGlstAyeLarrg..Vtllekgdia 32
                v++iGGG +G+ +A +Lar+g  ++lle+++++
  EEA22395.1  9 VLVIGGGPAGSYCASALAREGieTVLLEAEKFP 41
                99***************************9765 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 1.4
                 HHHHHHHTT-EEEESECEEEEE CS
         DAO 152 laraaealGveilegtevtgle 173
                 l r a + G++i+ g +v ++e
  EEA22395.1 113 LFRHAGTSGAKIFDGVKVNSIE 134
                 78889999**********9996 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.0   2.4e-05     0.031       1      30 [.      10      38 ..      10      50 .. 0.89
   2 ?    1.1   0.0      0.15   1.9e+02      76     121 ..     469     512 ..     440     529 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.4e-05
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEkg 30
                 ++iG+GPaG  +a +l + g+e  + lE +
   EEA22395.1 10 LVIGGGPAGSYCASALAREGIE-TVLLEAE 38
                 69*******************6.6799976 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.15
  Pyr_redox_3  76 eklsrkealeYlrevaksfelpiklfeeVesvkkedegfevetske 121
                  ek     al+ l++v +  +l+i +  + +++ + ++ f+vet  +
   EEA22395.1 469 EKY--SAALKELEAVLTPDQLHILQTIRARQMLRPEDMFTVETIGS 512
                  333..46789999*****************************9664 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.0     0.039        51       1      29 [.       9      37 ..       9      43 .. 0.86
   2 ?    6.8   0.0    0.0059       7.6      13      63 ..     383     432 ..     375     437 .. 0.86
   3 ?   -3.5   0.0       9.5   1.2e+04      60      87 ..     452     479 ..     449     494 .. 0.79

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.039
                EEEES-SHHHHHHHHHHHHTTEEEEEEES CS
      TrkA_N  1 iiiiGlGrvGrslaeeLseggkdvvvidk 29
                +++iG G  G+  a  L ++g++ v+ + 
  EEA22395.1  9 VLVIGGGPAGSYCASALAREGIETVLLEA 37
                68*****************8866777765 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.0059
                 HHHHHHHTTEEEEEEESSHHHHHHHHHTTSEEEES-TTSHHHHHHTTGGGE CS
      TrkA_N  13 laeeLseggkdvvvidkdeerveelreeglevvvgdatdeevLeeagieka 63 
                  +++++e+  + v+ d de+++e++ +++ ++++g +  +  L +a++++a
  EEA22395.1 383 ALKQINEKD-EPVISDFDEKTFERAFKHFRPIIQGTVDVQGKLSQAEVSQA 432
                 556666655.47999************************999999999887 PP

  == domain 3  score: -3.5 bits;  conditional E-value: 9.5
                 GGGESEEEE-SSSHHHHHHHHHHHHHHT CS
      TrkA_N  60 iekadaviaatgddeanilavllakeln 87 
                 iek++++ +  +dd +n   ++++kel 
  EEA22395.1 452 IEKMRSLAISDPDDLSNEKYSAALKELE 479
                 6788888888888888888888888765 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0    0.0001      0.13       2      35 ..       9      42 ..       8      58 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 0.0001
                EEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSS CS
   Pyr_redox  2 vvvvGgGyiglElAgalaelgkkVtvversdkll 35
                v+v+GgG  g  +A+ala+ g ++ ++e+++ ++
  EEA22395.1  9 VLVIGGGPAGSYCASALAREGIETVLLEAEKFPR 42
                89***********************999987776 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   0.00022      0.28      18      49 ..       7      37 ..       4      41 .. 0.92
   2 ?   -3.9   0.1         5   6.5e+03      20      61 ..     176     215 ..     172     219 .. 0.60

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00022
                EEEEEE--SHHHHHHHHHHHHCTTS-EEEEES CS
        Thi4 18 sDvvivGaGssGLtaayylakkpdlkvailer 49
                + v+++G+G++G  +a  la++ ++++++le+
  EEA22395.1  7 TTVLVIGGGPAGSYCASALARE-GIETVLLEA 37
                5699******************.*******97 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 5
                 EEEE--SHHHHHHHHHHHHCTTS-EEEEESSSS--TTTTTTS CS
        Thi4  20 vvivGaGssGLtaayylakkpdlkvailersvspGGGawlGG 61 
                  ++  +G  GL +++y  ++ ++++    +sv+  G  w GG
  EEA22395.1 176 YLVDASGRQGLVSTKYWKNR-KMNTGAQLQSVATWG-YWTGG 215
                 55556677777777776666.666666666776654.55555 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00011      0.15       2      34 ..       9      39 ..       8      61 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00011
  Lycopene_cycl  2 vvviGaGpAglslAarlteakpglkvvlieasp 34
                   v+viG+GpAg   A  l  a+ g++ vl+ea +
     EEA22395.1  9 VLVIGGGPAGSYCASAL--AREGIETVLLEAEK 39
                   89***************..**********9864 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (575 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       493  (0.0274974); expected 358.6 (0.02)
Passed bias filter:                      468  (0.026103); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.66u 0.29s 00:00:00.95 Elapsed: 00:00:00.46
# Mc/sec: 3736.88
//
Query:       EEA22396.1  [L=621]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00022   21.3  10.1    0.00044   20.3  10.1    1.5  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3  10.1   2.5e-08   0.00044       2      39 ..      19      57 ..      18      58 .. 0.86

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 2.5e-08
                S-HHHHHCT---ST...SSSS-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus  2 aCdnCrkkKvKCda...kkPaCsnCkklnleCtfysesskr 39
                aC+nC + K +C +   ++  C +C +l++eC+  + s +r
  EEA22396.1 19 ACTNCARAKYRCTYrpdRRQ-CERCLRLEKECV-TPVSARR 57
                9*************885555.************.8877766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (621 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       747  (0.0416643); expected 358.6 (0.02)
Passed bias filter:                      529  (0.0295053); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.32s 00:00:01.00 Elapsed: 00:00:00.52
# Mc/sec: 3583.78
//
Query:       EEA22397.1  [L=583]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.6e-42  144.2  50.1    2.1e-41  142.0  50.1    2.0  1  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  142.0  50.1   1.2e-45   2.1e-41       2     351 ..      69     470 ..      68     472 .. 0.89

  Alignments for each domain:
  == domain 1  score: 142.0 bits;  conditional E-value: 1.2e-45
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlga 99 
                  laa+l +l+ +i+++a+p  ++++++ s + +g+  ++y lg+a + +++G +   f++++++l+ ++lf +g++l+   +++  +l+v+r+++G+g+
  EEA22397.1  69 TLAAALLFLDTAIIATAIP-RITDQFN-SLADVGWYGGAYQLGSATLLPLTGKIYHYFSSKWTFLIFFTLFEIGSVLCGA-ATSSaMLIVGRAIAGMGG 164
                 6899***************.*******.**********************************************555553.55555************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee.......... 188
                 ++++++++++ia   p ++r+ a+g++++ ++lG++lgpl+gg++++   Wr++fyi+ +++ +++++ ll +  ++  +k+++ +  +          
  EEA22397.1 165 AGIISGALTIIASCMPLNKRATATGIMMGVSQLGVVLGPLIGGAFTQRTTWRWCFYINLPLGGVCILF-LLGIHIPDQVKKPNPLVV-Lrnlhhhldli 261
                 *****************************************************************774.344444444444444444.3599******* PP

       MFS_1 189 ................................................kgtgpaplvpawkallkdpvlw.illialllfffgfsglltllplylqevl 238
                                                                  + g  +l+p  k++ +++++w ++l+ +l++   ++ ++++lp+y+q v 
  EEA22397.1 262 gfvlfagsviqlllavelggnrfawnsatiiglfcgagatfllwfswnWRLGDEALIP--KSMTSKRPVWaSCLMQALSMV-TLFVVSYFLPTYFQAVQ 357
                 ********************99999999999999999999988888876677777777..888889989977777777774.8888************* PP

       MFS_1 239 glsglllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglallavtssavllll.vlvliGfglgfvfpsllalasdlappeeagt 336
                 + s  ll+g+ l  + ++ +i+a+l+g l+ ++g  ++  +++++l ++  gl+ + v++s++  ++   vl G+g g+v+ + + +++ ++ p+e  +
  EEA22397.1 358 NRS-PLLSGVQLLPSIIGQLIFAVLSGILVSKTGFVIPYAFIGAVLGAIGSGLFTTLVPDSSLGKWFgYQVLSGVGRGMVMQMPIIAMQASLEPKELSM 455
                 ***.688887777777777788*************************************9999999966777999************************ PP

       MFS_1 337 asglfntagslggal 351
                 a++l+++a+sl +++
  EEA22397.1 456 ANSLMMFAQSLLTSI 470
                 **********97765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (583 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       597  (0.033298); expected 358.6 (0.02)
Passed bias filter:                      285  (0.015896); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.75u 0.34s 00:00:01.09 Elapsed: 00:00:00.57
# Mc/sec: 3067.71
//
Query:       EEA22398.1  [L=444]
Description: hypothetical protein PMAA_061760 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.1e-08   32.4   3.7    7.1e-08   32.4   3.7    2.4  2  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.4   3.7     4e-12   7.1e-08       2      37 ..       9      42 ..       8      44 .. 0.93
   2 ?   -0.7   0.3     0.089   1.6e+03      18      26 ..     332     339 ..     328     342 .. 0.62

  Alignments for each domain:
  == domain 1  score: 32.4 bits;  conditional E-value: 4e-12
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfysess 37
                aCd C++ Kv+C++  P C +C ++++ C  ys  +
  EEA22398.1  9 ACDVCHQAKVRCSGTLP-CLKCSESGSLCF-YSLAK 42
                9****************.***********9.88766 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.089
                 SS-HHHHHC CS
     Zn_clus  18 PaCsnCkkl 26 
                 + C  C+++
  EEA22398.1 332 E-CNTCAQN 339
                 5.7777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (444 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       843  (0.0470188); expected 358.6 (0.02)
Passed bias filter:                      333  (0.0185733); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.32s 00:00:01.00 Elapsed: 00:00:00.54
# Mc/sec: 2471.61
//
Query:       EEA22399.1  [L=240]
Description: hypothetical protein PMAA_061770 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.026   14.9   1.2       0.08   13.4   0.3    2.1  2  ACP_PD    Acyl carrier protein phosphodiesterase
       0.23   11.8   3.2         12    6.4   0.8    3.3  4  Styelin   Styelin


Domain annotation for each model (and alignments):
>> ACP_PD  Acyl carrier protein phosphodiesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.3   8.9e-06      0.08      16     100 ..      52     140 ..      48     145 .. 0.81
   2 ?   -0.1   0.1      0.14   1.2e+03      37      69 ..     156     188 ..     135     204 .. 0.53

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 8.9e-06
      ACP_PD  16 pLeefvqrvyaqlekneealPerl.....qrllprmieedwLesYaelegieralqrmarrlkrasklaeaieeleenyaeleadFleff 100
                 ++e+++ +++++le+n +++P+ l     ++llpr++ +d  ++Y++++ i + l+ + + ++r ++ ++a++ l  n ++++    +f 
  EEA22399.1  52 KFESWLIDIENKLEANADHYPTALsreaaEHLLPRFR-KDSPQRYRDVDDIIEHLKTIYHDANRVTSAKRAFRRLYMNDTKFQVFLSKFV 140
                 5677788889999999999997762111145667766.8899**************************************9998777776 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.14
      ACP_PD  37 erlqrllprmieedwLesYaelegieralqrma 69 
                 + ++rl p+m ++   esY +    ++ +++  
  EEA22399.1 156 KLYERLSPEMQKQLVKESYDDTLSYQNFVRECH 188
                 444555555555555555555444444444443 PP

>> Styelin  Styelin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.8    0.0013        12      38      53 ..       9      24 ..       6      27 .. 0.90
   2 ?   -2.2   0.0      0.64   5.7e+03      32      50 ..      45      63 ..      41      67 .. 0.78
   3 ?    3.1   0.0     0.013   1.2e+02      35      57 ..     127     150 ..     102     152 .. 0.84
   4 ?   -0.6   0.0       0.2   1.8e+03      39      50 ..     179     190 ..     153     195 .. 0.69

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0013
     Styelin 38 eefqefmkeveqaree 53
                +e q+ ++eveq ree
  EEA22399.1  9 DEVQQQLHEVEQGREE 24
                689999*********9 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 0.64
     Styelin 32 LGDmtDeefqefmkeveqa 50
                L D  D  f  ++ ++e  
  EEA22399.1 45 LIDGKDPKFESWLIDIENK 63
                5677899999999999975 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.013
     Styelin  35 mtDeefqefmke.veqareeeLls 57 
                 m D  fq f+   v  a+e eL +
  EEA22399.1 127 MNDTKFQVFLSKfVLNAQESELPA 150
                 99*******965388999999966 PP

  == domain 4  score: -0.6 bits;  conditional E-value: 0.2
     Styelin  39 efqefmkeveqa 50 
                  +q+f++e  q 
  EEA22399.1 179 SYQNFVRECHQT 190
                 489999999885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (240 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       944  (0.0526521); expected 358.6 (0.02)
Passed bias filter:                      530  (0.029561); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1656.63
//
Query:       EEA22400.1  [L=320]
Description: hypothetical protein PMAA_061780 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.2e-07   31.3   0.0    6.7e-07   29.8   0.0    1.7  2  OrsD      Orsellinic acid/F9775 biosynthesis cluster protein 


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.8   0.0   3.7e-11   6.7e-07       8      95 ..      21      96 ..      17     101 .. 0.88
   2 ?   -2.9   0.0       0.5     9e+03      31      59 ..     143     171 ..     128     175 .. 0.63

  Alignments for each domain:
  == domain 1  score: 29.8 bits;  conditional E-value: 3.7e-11
        OrsD  8 eyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgLpvyeGyrCrakakC 95
                ++r+liC++C +a+ p+++++H  ++h+    e+++ l e++      rq d   +e++ v +++   +  p L +y+G+ Cr    C
  EEA22400.1 21 NFRLLICESCGFALGPNQASSHFWEKHQVS-IEQRHGLTEYL------RQHD--FQEPASVAPRPRGAPEHPALRTYNGLACR---LC 96
                5799********************998887.677999***99......8888..79999999999999999***********4...34 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.5
        OrsD  31 rkrhrqlkrektqelletvehemslrqld 59 
                 r+rh  ++ +++q    ++  ++slr++ 
  EEA22400.1 143 RTRHAAIQAATVQDSGIATRSFESLRPWI 171
                 45666666666555555555556666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (320 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       509  (0.0283898); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 2353.58
//
Query:       EEA22401.1  [L=317]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (317 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       465  (0.0259356); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.47u 0.25s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2339.63
//
Query:       EEA22402.1  [L=328]
Description: hypothetical protein PMAA_061800 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (328 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       461  (0.0257125); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 2161.96
//
Query:       EEA22403.1  [L=743]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.7e-13   49.3   0.0    1.5e-12   47.9   0.0    1.7  1  OrsD      Orsellinic acid/F9775 biosynthesis cluster protein 


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.9   0.0   8.4e-17   1.5e-12       3      93 ..      12      97 ..      10     102 .. 0.88

  Alignments for each domain:
  == domain 1  score: 47.9 bits;  conditional E-value: 8.4e-17
        OrsD  3 feyneeyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgLpvy.eGyrCraka 93
                fe+  ++ v+iCreC+y+v+ps++e HL++ h++++   + +l  +v      r++ ++a ++ ++++p++  + ip+L    +G +C+ ++
  EEA22403.1 12 FERLVDFPVVICRECQYGVWPSQIEGHLQRAHQHISPMIRIQLGDEV------RSWPNIAIDPIELEIPPTRTQAIPQLIGPlDGWQCQLSP 97
                78888999*********************888888777677788888......*************************98766*****7666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (743 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       479  (0.0267165); expected 358.6 (0.02)
Passed bias filter:                      379  (0.0211389); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.64u 0.30s 00:00:00.94 Elapsed: 00:00:00.46
# Mc/sec: 4858.66
//
Query:       EEA22404.1  [L=933]
Description: DNA helicase recq, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    3.9e-14   52.8   0.1      9e-14   51.6   0.1    1.6  1  DEAD        DEAD/DEAH box helicase
    2.4e-13   50.4   0.0      6e-13   49.1   0.0    1.7  1  Helicase_C  Helicase conserved C-terminal domain
    5.6e-06   26.5   0.0    1.9e-05   24.7   0.0    2.0  2  ResIII      Type III restriction enzyme, res subunit


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.6   0.1   1.5e-17     9e-14       3     174 ..     337     489 ..     335     491 .. 0.78

  Alignments for each domain:
  == domain 1  score: 51.6 bits;  conditional E-value: 1.5e-17
                 HHHHHHHHHHTTC.EEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTCSE CS
                 xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   3 iQaeaiplilggg.dvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngvdi 100
                  Q+++i+ i++ +  +++ ++TG+GK+l f++p+         ++g  +++v+P+ +L  +  +++++++         +++     d ++ +  g+ i
  EEA22404.1 337 TQKAVIQSIVQRQsPIVAIMPTGAGKSLLFMLPAW-------MSRGGTTIVVVPLVALRADLQQRCQTLGIS-------CVE----WDSRRPV-DGASI 416
                 599*******766378899****************.......4677899************99999999984.......233....4555777.8999* PP

                 EEEEHHHHHHHH.....HCTSSHCTTEEEEEEETHHHHHHT..TTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHHH CS
                 xxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD 101 vvgtpgrlddll.....stgklnlsqvrflVlDEadrlldq..gfsdfinrilnqlpqitcdgklqrqvivlSATlpkdvk 174
                 v+ tp+  ++ +     + +k  ++++  +V+DE++ +l++  +f++++ ++ +         +++ q+++l+ATlp++ +
  EEA22404.1 417 VLVTPESAVSETfqtfiN-RKQWTKELDRIVIDECHIILQEgyQFRKQMAQLGAL-------VRAETQLVLLTATLPRESE 489
                 *****9999966465533.343599****************44444555553333.......345567*********8765 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.1   0.0     1e-16     6e-13      12     110 ..     544     635 ..     534     636 .. 0.89

  Alignments for each domain:
  == domain 1  score: 49.1 bits;  conditional E-value: 1e-16
                 HTTTTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSSHHHHHHHHTTSSST CS
  Helicase_C  12 leeeggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprnvtsyiqriGRtgRa 110
                 ++ ++gk++i++nti +++    +   +++++ ++++  ++ +++ +l++f+k++  v++at+++++Gidip+++lVi+++  r++ +y q +GR+gR 
  EEA22404.1 544 QQLHEGKVVIYANTIATVQ---RI--AHQLQCPAYYS--QAVDKKGMLASFQKQNPGVIVATSALGMGIDIPDIRLVIHVGRTRSLLDYGQESGRAGRD 635
                 56689*************5...55..46689999999..89999*******887777*****************************************6 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.0   3.3e-09   1.9e-05       7     170 ..     337     485 ..     301     486 .. 0.78
   2 ?   -2.6   0.0      0.78   4.6e+03      41      75 ..     535     569 ..     533     592 .. 0.75

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 3.3e-09
                 HHHHHHHHHT......TTSEEEEEESTTSTHHHHHHHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--.......-S CS
      ResIII   7 yQeeaienlleklkskrdkrglikmaTGtGKTlvaaklierllkkgkeekflflvprkslleqtleefkkflseaykeigkkvsgdkkkakekdstnkk 105
                  Q+ +i++++     +r+  ++  m+TG+GK+l+ +  ++  +       ++++vp  +l   ++++ + +  +++     ++++++          ++
  EEA22404.1 337 TQKAVIQSIV-----QRQSPIVAIMPTGAGKSLLFMLPAWMSRGG----TTIVVVPLVALRADLQQRCQTLGISCV-----EWDSRRPVD------GAS 415
                 4555555444.....8999**************999999988875....89*********************9874.....666666666......889 PP

                 EEEEEHHHHHHTH........HHHTTT-SEEEEETGGGTTS......TTTHHHHHT-.--SEEEEEESS-S CS
      ResIII 106 ilvttiqsldadseeeeeeseellrdrfdviiiDEaHrlgak.....kswreilekf.keavllglTATpe 170
                 i+++t +s+ ++   ++  + ++  ++ d i+iDE+H + ++     k++ ++   +  e  l+ lTAT++
  EEA22404.1 416 IVLVTPESAVSET-FQTFINRKQWTKELDRIVIDECHIILQEgyqfrKQMAQLGALVrAETQLVLLTATLP 485
                 9999999988888.4456666667777779*******9999655555566666333324477778899986 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 0.78
                 HHHHHHHH-S.....-EEEEESSHHHHHHHHHHGG CS
      ResIII  41 aaklierllkkgkeekflflvprkslleqtleefk 75 
                 ++  i++  ++ +e k+++ +++++ +++  ++++
  EEA22404.1 535 MITWIQQRVQQLHEGKVVIYANTIATVQRIAHQLQ 569
                 67778888888888899999999988888776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (933 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       562  (0.0313459); expected 358.6 (0.02)
Passed bias filter:                      441  (0.024597); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.74u 0.32s 00:00:01.06 Elapsed: 00:00:00.50
# Mc/sec: 5614.34
//
Query:       EEA22405.1  [L=1500]
Description: DNA helicase recq, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.9e-12   46.6  12.4    4.2e-12   46.5   9.6    2.6  2  OrsD          Orsellinic acid/F9775 biosynthesis cluster prot
    8.2e-12   45.4   0.0      1e-10   41.9   0.0    2.7  3  Helicase_C    Helicase conserved C-terminal domain
    4.6e-11   42.8   0.0    1.7e-10   41.0   0.0    2.0  1  DEAD          DEAD/DEAH box helicase
    0.00085   19.4   0.0      0.002   18.2   0.0    1.6  1  ResIII        Type III restriction enzyme, res subunit
  ------ inclusion threshold ------
      0.016   15.9   0.1      0.058   14.1   0.1    2.0  1  RecQ_Zn_bind  RecQ zinc-binding
      0.035   13.7   3.0       0.19   11.3   3.0    2.3  1  zf-C2H2_12    Zinc-finger C2H2-type
       0.13   11.5   0.0       0.23   10.7   0.0    1.3  1  Peptidase_S8  Subtilase family


Domain annotation for each model (and alignments):
>> OrsD  Orsellinic acid/F9775 biosynthesis cluster protein D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.5   9.6   1.6e-15   4.2e-12       1     114 []       8     118 ..       8     118 .. 0.86
   2 ?   -2.0   0.0       1.8   4.6e+03      35      63 ..     504     531 ..     495     545 .. 0.71

  Alignments for each domain:
  == domain 1  score: 46.5 bits;  conditional E-value: 1.6e-15
        OrsD   1 dlfeyneeyrvliCreCkyavlpselerHLrkrhrqlkrektqelletvehemslrqldelareaeavslpsaesepipgL..pvyeGyrCrakakCky 97 
                 ++f+y++++r++iC  C++ v  s+l +HLr+  +  +    ++ ++ +  ++  +q+ e  r++ ++ +p+++ +pipgL  p    y+C   ++C++
  EEA22405.1   8 QIFQYDPHHRIVICCLCQHVVFDSQLPSHLRNTRHIRE----RHSQHIILFQQYHQQFPERIRHHRELVIPHKPIAPIPGLipPRDPTYQC-SYPGCHW 101
                 57*****************************5544443....34556665557788999999******************96555699***.78***** PP

        OrsD  98 ltrslktlrkHlqkkhg 114
                 +  +++++++H +++hg
  EEA22405.1 102 IGETIRRIHDHCRQEHG 118
                 **************995 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.8
        OrsD  35 rqlkrektqelletvehemslrqldelar 63 
                  q++r ++ +l+etv h    r +d+l++
  EEA22405.1 504 YQHHRFTMDQLRETV-HGIINRAWDHLTQ 531
                 456666788999999.8888899996644 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0       5.4   1.4e+04      16      54 ..     942     980 ..     939     986 .. 0.70
   2 ?   -0.6   0.0      0.65   1.7e+03      57      89 ..    1068    1101 ..    1037    1108 .. 0.83
   3 !   41.9   0.0   3.9e-14     1e-10      15     110 ..    1113    1212 ..    1100    1213 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 5.4
                 TSEEEEEESSHH.HHHHHHHHHHHTTSTEEEESTTSTHHH CS
  Helicase_C  16 ggkilifvntid.rlekvklllekkgikvavlhgelpqne 54 
                  g+++++v+t++ r ++ +    + gi++++ ++  p + 
  EEA22405.1 942 AGTSIVVVPTVSlRQDMQREC-AQAGISCVPWNSHRPPET 980
                 678899999999766543333.466899999998887765 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.65
                  HHHHHHH.TTSSSEEEESGGGTSSSTSTTESEEE CS
  Helicase_C   57 eileqfn.kgesdvLiatdvaerGidipkvnlVi 89  
                   ++++f+  ++++v ia +v ++++d+++ ++V 
  EEA22405.1 1068 TVVQRFRsPHTTRVNIAYRVESMSVDVDEDEVVA 1101
                  57899*944555599************9887776 PP

  == domain 3  score: 41.9 bits;  conditional E-value: 3.9e-14
                  TTSEEEEEESSHHHHHHHHHHHHHTTSTEEEESTTSTHHHHHHHHHHHH...TTS.....SS.EEEESGGGTSSSTSTTESEEEESSSSSSHHHHHH CS
  Helicase_C   15 eggkilifvntidrlekvklllekkgikvavlhgelpqnereeileqfn...kge.....sd.vLiatdvaerGidipkvnlVinfdlprnvtsyiq 102 
                  +gg+i+++   + ++   + l     + ++++hg++    +e++l++f    +g+     s   ++at+++++Gi+i  v++Vi++++p  +++y q
  EEA22405.1 1113 RGGQIIVYRSETGDV---DAL--ATRLGCLAYHGKMAVAMKEHALQAFTphpEGTtdpirSGmTIVATNALGMGINIRTVRCVIHVEVPSMLREYSQ 1204
                  677888888888888...455..4568999******************96654556666533479******************************** PP

                  HHTTSSST CS
  Helicase_C  103 riGRtgRa 110 
                   +GR+gR 
  EEA22405.1 1205 ESGRAGRD 1212
                  *******6 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.0   0.0   6.5e-14   1.7e-10       3     173 ..     904    1054 ..     902    1058 .. 0.77

  Alignments for each domain:
  == domain 1  score: 41.0 bits;  conditional E-value: 6.5e-14
                  HHHHHHHHHHTTC.EEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHHTTC CS
                  xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD    3 iQaeaiplilggg.dvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskldngv 98  
                  iQ++ai++++g    vl+ + TG GK+++f++p+    +    +++   ++v+Pt +L +++ +++ + +      ++ + +  +         +++
  EEA22405.1  904 IQKAAIDAVMGSApWVLGVMGTGGGKSMIFMVPAA---W----ERAGTSIVVVPTVSLRQDMQRECAQAGIS----CVPWNSHRPP--------ETA 981 
                  9*********66559********************...4....456689*******************9994....2222222222........456 PP

                  SEEEEEHHHHHHHH.....HCTSSHCTTEEEEEEETHHHHHHT..TTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHH CS
                  xxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   99 divvgtpgrlddll.....stgklnlsqvrflVlDEadrlldq..gfsdfinrilnqlpqitcdgklqrqvivlSATlpkdv 173 
                  +iv+ tp+   +       s +  + +++  +V+DE++++ld+  +f++++  ++  +   t   +    v++l+ATlp  v
  EEA22405.1  982 RIVLVTPESATSKGfrsyiS-RLQERNRLDRIVIDECHTILDSreEFRPKMAGLHVLM---TIGSP----VVLLTATLP-AV 1054
                  78999998888844354432.2223788899***********9888888888877777...44445....********9.44 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0   7.8e-07     0.002      29     147 ..     921    1023 ..     900    1053 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 7.8e-07
                  EEESTTSTHHHHH.HHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--.......-SEEEEEHHHHHHTH...... CS
      ResIII   29 ikmaTGtGKTlva.aklierllkkgkeekflflvprkslleqtleefkkflseaykeigkkvsgdkkkakekdstnkkilvttiqsldadseeeeee 124 
                   +m TG GK+++  + ++++ +        +++vp+ sl + +++e ++   +++      +++ +  +      +++i+++t +s++++   +++ 
  EEA22405.1  921 GVMGTGGGKSMIFmVPAAWERAG-----TSIVVVPTVSLRQDMQRECAQAGISCV-----PWNSHRPPE------TARIVLVTPESATSKG-FRSYI 1000
                  5899******9985677777776.....689********************9875.....677777777......9999999999999988.56999 PP

                  ..HHHTTT-SEEEEETGGGTTS. CS
      ResIII  125 seellrdrfdviiiDEaHrlgak 147 
                  s  ++r+r d i+iDE+H + ++
  EEA22405.1 1001 SRLQERNRLDRIVIDECHTILDS 1023
                  9999**************98875 PP

>> RecQ_Zn_bind  RecQ zinc-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.1   2.3e-05     0.058      28      65 ..    1242    1282 ..    1220    1283 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 2.3e-05
  RecQ_Zn_bind   28 leamlaycentteCrrkllleyFgeeaaeeeC..gn..CDnC 65  
                     +am +y + t+ Crr +l  y +  +  + C  g+  CD C
    EEA22405.1 1242 KQAMREYFHGTR-CRRAVLDAYLDSYERPDGCtdGEapCDQC 1282
                    589*****6666.**********98777778*662266**99 PP

>> zf-C2H2_12  Zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   3.0   7.4e-05      0.19      14      59 ..      10      58 ..       6      64 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 7.4e-05
  zf-C2H2_12 14 mdydpqrrglvCmvCgeslaslkl.stik..rHIrqvHPeslslseeek 59
                  ydp++r ++C  C+++    +l s+++  rHIr++H + + l ++ +
  EEA22405.1 10 FQYDPHHRIVICCLCQHVVFDSQLpSHLRntRHIRERHSQHIILFQQYH 58
                68***************999999844554338******99877766655 PP

>> Peptidase_S8  Subtilase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   9.1e-05      0.23      49      88 ..     797     838 ..     711     847 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 9.1e-05
                   S-TT-SC-SSS......HHHHHHHHHH-B..SSSSSB-SSTT CS
                   xxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8  49 tstnwarddngnsie..HGthvAGiaaanapeegekngvapg 88 
                       w++dd + +i+  HG+hvAG++ a   ee      a +
    EEA22405.1 797 DGCWWTADDAVIDIQagHGSHVAGMIYARGVEEAPGTMAAMK 838
                   34447778877777799**********995555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1500 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       660  (0.0368119); expected 358.6 (0.02)
Passed bias filter:                      457  (0.0254894); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.94u 0.28s 00:00:01.22 Elapsed: 00:00:00.48
# Mc/sec: 9310.33
//
Query:       EEA22406.1  [L=1096]
Description: copia protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.6e-61  206.9   0.0    5.5e-61  206.3   0.0    1.3  1  RVT_2            Reverse transcriptase (RNA-dependent DNA pol
    2.7e-17   63.0   0.0    1.4e-16   60.8   0.0    2.2  2  rve              Integrase core domain
    7.6e-10   38.5   0.2    3.9e-09   36.2   0.1    2.3  2  gag_pre-integrs  GAG-pre-integrase domain
     0.0086   15.8   0.1      0.045   13.5   0.0    2.2  2  rve_3            Integrase core domain
  ------ inclusion threshold ------
      0.092   12.2   0.0        0.2   11.1   0.0    1.5  1  RVT_1            Reverse transcriptase (RNA-dependent DNA pol


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  206.3   0.0   1.5e-64   5.5e-61       2     241 ..     615     854 ..     614     855 .. 0.96

  Alignments for each domain:
  == domain 1  score: 206.3 bits;  conditional E-value: 1.5e-64
       RVT_2   2 tyrlvslPkdrkaigsrWvftkkkddl.kevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeeelvvhqldvdsafLnaeldeevyvkq 99 
                 t+r v+ P ++  i+ +Wvf +k ++  +  ++karlva+Gfsq+ g d++++faPvirl+s+r+l a+aa+++l  h ld   af+ ++ld+++y+  
  EEA22406.1 615 TWRFVKRPDHKAVISCKWVFDIKYQADgRIERFKARLVARGFSQQEGLDFEDTFAPVIRLESLRVLFAIAAMYGLTAHLLDATNAFVGSKLDKQIYMEV 713
                 8**********************988768899******************************************************************* PP

       RVT_2 100 PpGfeidre..eekvykLnkslyGlkqapllWnekidkvLkklgferseaesGlyvrgtgegklivalyvddlliagsdikiledvkkelakkfklkdl 196
                 P G     +  +++v++L +slyGl+q++ lW +k++k+++ +gf++s+a  G ++        i+alyvdd+l+ +++ k +e  k++l++ + +kd 
  EEA22406.1 714 PKGLPKSLQprKDEVCELLQSLYGLRQSANLWCHKVKKFVTSIGFKPSTADPGTFINER---GTIIALYVDDILVFSKNEKAIELTKEKLKEFHPMKDS 809
                 ***97765511688******************************************984...369********************************** PP

       RVT_2 197 gkvskfLGieiaqeaggiklsladyiakvvkkfeltdaktvatPl 241
                 g+v+k LGi i+   g i+l ++ y  +++++f++ ++k+++ Pl
  EEA22406.1 810 GRVNKILGIRITWLDGSIRLDQEFYTIRILEEFDMLESKPQMLPL 854
                 ****************************************99997 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.8   0.0   3.8e-20   1.4e-16       2     115 ..     168     281 ..     167     283 .. 0.94
   2 ?   -2.5   0.0       1.5   5.4e+03      81     100 ..     747     766 ..     741     767 .. 0.88

  Alignments for each domain:
  == domain 1  score: 60.8 bits;  conditional E-value: 3.8e-20
         rve   2 trpgelwqvDvt.vvripdgggkayllvvvddfsrlilaealsdemdastvlalleravarfggve...pervlsDngseytskafrefladlgirvsf 96 
                 ++p e+++vD++  +r ++ g++ay l ++dd++r+ ++++++++   +tv+++l r ++r+  +       ++ Dn++e++  a++ +++dlgi+++f
  EEA22406.1 168 KKPLERVSVDFWgPYR-KGEGKEAYYLSITDDATRFSWIHITDNR-RLETVQRILSRWMRRQERELgvfLVNIRLDNAKEFV--ALKPWAEDLGIDLEF 262
                 589**********888.67777***********************.*************999885599999***********..*************** PP

         rve  97 trpgrpqdnGkvErfhrtl 115
                 t  + p +nG++Er +r+l
  EEA22406.1 263 TEFYTPAQNGIAERLNRLL 281
                 *****************98 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 1.5
         rve  81 kafrefladlgirvsftrpg 100
                 +++++f+ + g+++s++ pg
  EEA22406.1 747 HKVKKFVTSIGFKPSTADPG 766
                 68899***********9998 PP

>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2   0.1   1.1e-12   3.9e-09      18      67 .]     109     155 ..      92     155 .. 0.83
   2 ?   -1.7   0.0      0.76   2.7e+03      44      60 ..     714     730 ..     711     733 .. 0.85

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 1.1e-12
  gag_pre-integrs  18 sknkssinlWHrRLGHpsfsrlkkLfkkgllpglkisksevCeaCqlgKq 67 
                      + +  + +l HrR+GH +++r+++L+k+    g+++++s+ Ce+C+++K+
       EEA22406.1 109 QEKQPDWELLHRRFGHAGERRMRRLAKR---LGITFKDSKDCEVCIQAKS 155
                      44677899******************98...688999************6 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.76
  gag_pre-integrs  44 kkgllpglkisksevCe 60 
                      +kgl ++l++ k+evCe
       EEA22406.1 714 PKGLPKSLQPRKDEVCE 730
                      6778889999******9 PP

>> rve_3  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.1      0.83     3e+03      30      51 ..     204     225 ..     200     226 .. 0.81
   2 !   13.5   0.0   1.2e-05     0.045       2      27 ..     257     282 ..     256     296 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.83
       rve_3  30 llneelfrslaearekleawre 51 
                 ++  +  r+l++++++l +w +
  EEA22406.1 204 WIHITDNRRLETVQRILSRWMR 225
                 5566677899**********87 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 1.2e-05
       rve_3   2 gielsyiapgkPqqNglvEsfngtlr 27 
                 gi l++++ ++P qNg +E++n+ l 
  EEA22406.1 257 GIDLEFTEFYTPAQNGIAERLNRLLL 282
                 899*******************9876 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   5.7e-05       0.2     159     190 ..     772     803 ..     741     808 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 5.7e-05
                 ...TEEECTTEEEEEESSHHHHHHHHHHHHHH CS
       RVT_1 159 kgvtllrYaDDililskskeelqelleaveew 190
                  g  +++Y+DDil++sk++++++   e+++e+
  EEA22406.1 772 RGTIIALYVDDILVFSKNEKAIELTKEKLKEF 803
                 48899**************9988777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1096 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       526  (0.0293379); expected 358.6 (0.02)
Passed bias filter:                      405  (0.0225891); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.76u 0.31s 00:00:01.07 Elapsed: 00:00:00.49
# Mc/sec: 6755.34
//
Query:       EEA22407.1  [L=654]
Description: hypothetical protein PMAA_090370 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.6e-19   69.2   0.8    2.6e-19   69.2   0.8    2.4  2  Exo_endo_phos_2  Endonuclease-reverse transcriptase
     0.0021   17.6   1.1     0.0032   17.0   0.3    1.7  2  Exo_endo_phos    Endonuclease/Exonuclease/phosphatase family
  ------ inclusion threshold ------
      0.078   12.7   0.2       0.14   11.8   0.2    1.4  1  DUF4300          Domain of unknown function (DUF4300)


Domain annotation for each model (and alignments):
>> Exo_endo_phos_2  Endonuclease-reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.2   0.8   4.4e-23   2.6e-19      28     118 ..     190     283 ..     162     284 .. 0.89
   2 ?   -1.3   0.2       0.3   1.8e+03      43      80 ..     508     543 ..     506     551 .. 0.80

  Alignments for each domain:
  == domain 1  score: 69.2 bits;  conditional E-value: 4.4e-23
  Exo_endo_phos_2  28 lksp.kiiilGDfNakhplWgsedtdssargeeLiefleehslsllnllksgptfkssngsstiDltltsdnlals...kleleeedlgSDHrp 117
                       ++  +++ilGDfN++hp+Wg+  t+ +a++e+L+e++++h+++++ ++  + t++++++ stiDltl s+ l+++   + +  + d+ SDH p
       EEA22407.1 190 SDRDrEHVILGDFNLHHPSWGGAGTQGDAEAEDLLEIMDSHDMEIVTEPG-VATWERNDQRSTIDLTLISNGLLERlvsCVRGDDIDHDSDHWP 282
                      444459****************777779****************888755.8*****999******************98999999*******9 PP

  Exo_endo_phos_2 118 i 118
                      i
       EEA22407.1 283 I 283
                      8 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.3
  Exo_endo_phos_2  43 hplWgsedtdssargeeLiefleehslsllnllksgpt 80 
                      + lW+ +++   +  + +i++ ++++l++ + l++ +t
       EEA22407.1 508 ERLWKRQKSA--KPTKRIIKAPHAKNLHYWQSLRKATT 543
                      5678885555..99999***********9998887776 PP

>> Exo_endo_phos  Endonuclease/Exonuclease/phosphatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.3   5.3e-07    0.0032     135     233 .]     184     280 ..     124     280 .. 0.84
   2 ?   -2.9   0.0      0.65   3.9e+03      94      94 ..     410     410 ..     340     498 .. 0.56

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 5.3e-07
                    HHHHHHHHTTSEEEEEEE-SSSTSGGGBSCGHHHHHHCTTTHH....SSCESCETTTTTTTTTTTEB-BEEEEEEC.HHHCCEEEEEEECCHHEEC CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxx RF
  Exo_endo_phos 135 qvealnadrgapvivaGDfNarpsdddsrvlrtrglalapapv....glyllgggptptyvtraggsrlDrilasp.alalfrsgvlppplalvrr 225
                     + ++  dr++  +++GDfN ++ +++   ++  ++a +   +    +    +   ++t+ ++  +s++D +l s+  l++ +s+v  +  +    
     EEA22407.1 184 IGXINASDRDREHVILGDFNLHHPSWGGAGTQGDAEAEDLLEImdshDMEIVTEPGVATWERNDQRSTIDLTLISNgLLERLVSCVRGDDIDH--- 276
                    5566778899999*****************999999998888678899999999999999999999*********977777777776654433... PP

                    TSSCSSSB CS
                    xxxxxxxx RF
  Exo_endo_phos 226 ealtlSDH 233
                         SDH
     EEA22407.1 277 ----DSDH 280
                    ....2777 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.65
                    T CS
                    x RF
  Exo_endo_phos  94 f 94 
                     
     EEA22407.1 410 G 410
                    1 PP

>> DUF4300  Domain of unknown function (DUF4300)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.2   2.4e-05      0.14       8      76 ..      41     108 ..      33     118 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 2.4e-05
     DUF4300   8 kesqkevkkaLkeagiskknvdaflesVnefnktv.ekkellkkgfeklkkkkpkydevkiqdawekknk 76 
                 ++s +e+  ++ ++ i+  ++ +f++sV++f+++v +++  l+k ++ l  ++ + d+ +i d+++k++ 
  EEA22407.1  41 AKSAHEMLLYMGNQAIKDPTIFNFIRSVKNFANAVpKRDGELDKVWQAL--NSIQRDTAQIRDKVSKSST 108
                 5677888889999**********************666778******77..7888999999999998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (654 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       616  (0.0343577); expected 358.6 (0.02)
Passed bias filter:                      468  (0.026103); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.67u 0.28s 00:00:00.95 Elapsed: 00:00:00.49
# Mc/sec: 3989.77
//
Query:       EEA22408.1  [L=52]
Description: hypothetical protein PMAA_090380 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (52 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       332  (0.0185175); expected 358.6 (0.02)
Passed bias filter:                      204  (0.0113782); expected 358.6 (0.02)
Passed Vit filter:                         9  (0.00050198); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.32u 0.24s 00:00:00.56 Elapsed: 00:00:00.37
# Mc/sec: 420.26
//
Query:       EEA22409.1  [L=1121]
Description: hypothetical protein PMAA_090390 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.9e-09   36.6   0.1    6.2e-09   35.6   0.1    1.5  1  gag_pre-integrs  GAG-pre-integrase domain
    1.4e-05   25.2   0.3    4.1e-05   23.8   0.1    1.8  2  rve              Integrase core domain


Domain annotation for each model (and alignments):
>> gag_pre-integrs  GAG-pre-integrase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.6   0.1   6.9e-13   6.2e-09       2      64 ..     348     430 ..     347     431 .. 0.72

  Alignments for each domain:
  == domain 1  score: 35.6 bits;  conditional E-value: 6.9e-13
  gag_pre-integrs   2 LYlldlssnanssv.........slskn..kssinlWHrRLGHpsfsrlkkLfk........kgllpglkisk.sevCeaCql 64 
                      LY ++++  ++s+          s++k+  k+s+  WH+R GH+s +++kkL +         + l+g+++++ +e+Ce+C++
       EEA22409.1 348 LYFVKWNAKPSSNPplrnelafsSFEKTtlKDSALAWHKRYGHVSLKAIKKLEDaiegaivtTSELHGKNEDDlQEKCEICAM 430
                      8999998666643322333322256665678**********************98888887744467766666588*****85 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.8   0.1   4.5e-09   4.1e-05       4     115 ..     448     557 ..     445     560 .. 0.85
   2 ?   -3.4   0.0       1.2   1.1e+04      52      95 ..    1018    1068 ..     999    1071 .. 0.64

  Alignments for each domain:
  == domain 1  score: 23.8 bits;  conditional E-value: 4.5e-09
         rve   4 pgelwqvDvtvvripdgggkayllvvvddfsrlilaealsdemdastvlalleravarfggvepervlsDngseytskafrefladlgirvsftrpgrp 102
                 + + + vD+ v+      ++ y l+ v+ f ++     +++++  +++ a++e+    f    +e+v++D  s+    afr++++  ++ + +t p  p
  EEA22409.1 448 AFHTLFVDIIVMT-QAITREQYALHTVCPFAKFHALATVDSKAVVADMKAIIEKIEHTFRTH-VEVVHTDGESSLNGLAFRTWCNGRHTLLYVTVPDTP 544
                 5566788888666.344457899999999999999999999988888888888777777776.************************************ PP

         rve 103 qdnGkvErfhrtl 115
                 ++nG  Er+ +++
  EEA22409.1 545 EQNGPSERAGGLI 557
                 ********87776 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 1.2
         rve   52 lalleravarfggve..pervlsDngseytsk.....afrefladlgirvs 95  
                  l++++r +++ g      + +++Dn  ++        +fr+ l++ +i + 
  EEA22409.1 1018 LHVWKRVFKSIGYTPdrELCIQCDNKQTILLLtaedpQFRTNLKHVDIYHH 1068
                  456666666666653445557778877666446666677777777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1121 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       792  (0.0441742); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.73u 0.28s 00:00:01.01 Elapsed: 00:00:00.43
# Mc/sec: 7896.73
//
Query:       EEA22410.1  [L=599]
Description: retrovirus polyprotein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.2e-18   66.0   0.2    6.8e-18   64.9   0.2    1.6  1  RT_RNaseH    RNase H-like domain found in reverse transcripta
    7.6e-17   61.6   0.0    1.6e-16   60.6   0.0    1.6  1  rve          Integrase core domain
    2.9e-05   24.0   0.0     0.0001   22.2   0.0    1.9  2  RT_RNaseH_2  RNase H-like domain found in reverse transcripta


Domain annotation for each model (and alignments):
>> RT_RNaseH  RNase H-like domain found in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.9   0.2   1.1e-21   6.8e-18      41     105 .]       2      70 ..       1      70 [. 0.92

  Alignments for each domain:
  == domain 1  score: 64.9 bits;  conditional E-value: 1.1e-21
                 -HHHHTS-HHHHHHHHHHHHHHHHHHHHTS..--..EEEE-SS--TTTTT----.---HHHHHHHC-XX CS
   RT_RNaseH  41 sgaernystiekellAivaalkkfrhylqg..rk..ftvitDhknlkyllskkslngrlarWaleLsey 105
                 ++ae ny++++ke+lAi+ al+++r+ l g  r+  f++++Dh++l+y++++k+ln+r+arW+++L++y
  EEA22410.1   2 QSAELNYDIHDKEMLAIISALEEWRPELVGlqREdrFKILSDHRALEYFMTSKKLNARQARWCEFLHDY 70 
                 789***********************9877643357******************************998 PP

>> rve  Integrase core domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.6   0.0   2.6e-20   1.6e-16       2     118 ..     224     338 ..     223     339 .. 0.96

  Alignments for each domain:
  == domain 1  score: 60.6 bits;  conditional E-value: 2.6e-20
         rve   2 trpgelwqvDvtvvripdgggkayllvvvddfsrlilaealsdemdastvlalleravarfggvepervlsDngseytskafrefladlgirvsftrpg 100
                 trp +++++D+++++  d++g   ++vvvd fs+  + +++ +  +a+++++l+   + r+ g  p++++sD+g++++s+ + e+++ lgi++ ++ + 
  EEA22410.1 224 TRPWQHLSMDFMTYP-TDRNGYDTVFVVVDRFSKIPISIPCHKTVTAKDLARLWVLHLYRRTGP-PDTIVSDRGPQFVSEFWGEVCKILGIQIVLSTAD 320
                 7899********999.67777****************************************999.********************************** PP

         rve 101 rpqdnGkvErfhrtlkde 118
                 ++q+ G  E ++++l ++
  EEA22410.1 321 HAQTDGQTEIANQYLSQR 338
                 **************9886 PP

>> RT_RNaseH_2  RNase H-like domain found in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.2   0.0   1.7e-08    0.0001      66      95 ..       2      31 ..       1      38 [. 0.91
   2 ?   -2.9   0.0       1.2   7.3e+03      60      73 ..      51      64 ..      46      66 .. 0.85

  Alignments for each domain:
  == domain 1  score: 22.2 bits;  conditional E-value: 1.7e-08
  RT_RNaseH_2 66 skaernysttekellAivwalkkfrhyllg 95
                 ++ae ny++++ke+lAi+ al+++r+ l g
   EEA22410.1  2 QSAELNYDIHDKEMLAIISALEEWRPELVG 31
                 789***********************9988 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.2
  RT_RNaseH_2 60 faSrklskaernys 73
                 + S+kl++++ +++
   EEA22410.1 51 MTSKKLNARQARWC 64
                 579*****999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (599 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       458  (0.0255452); expected 358.6 (0.02)
Passed bias filter:                      408  (0.0227564); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.46
# Mc/sec: 3931.30
//
Query:       EEA22411.1  [L=397]
Description: aspartic endopeptidase Pep1/aspergillopepsin F [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.2e-55  186.4   0.0    9.7e-55  186.2   0.0    1.0  1  Asp             Eukaryotic aspartyl protease
     0.0024   18.1   0.0        2.8    8.2   0.0    2.8  3  TAXi_N          Xylanase inhibitor N-terminal
  ------ inclusion threshold ------
      0.025   15.2   0.1        3.2    8.5   0.0    2.8  2  Asp_protease_2  Aspartyl protease


Domain annotation for each model (and alignments):
>> Asp  Eukaryotic aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  186.2   0.0   1.6e-58   9.7e-55       1     314 [.      89     395 ..      89     396 .. 0.92

  Alignments for each domain:
  == domain 1  score: 186.2 bits;  conditional E-value: 1.6e-58
                 EEEEEEEETTTTEEEEEEEETT--SEEEEBTTESTSHCHHTSS-B-GGG-TT-EEEEEEEEEECTTS.EEEEEEEEEEEEETTEEEEEEEEEEEEEESS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp   1 eYfgeisiGtpeqkftvifDTGSsdlWVpsskckkssackshstydpskSstykkngkslsisYGdg.svsGflsqdtvkvggltvknqefgeatkepg 98 
                 eY++++ +G +  ++ ++fDTGSs+lWV+ +++k      sh+tyd++  + +   +++++++YGd   ++G+++ dtv++gg+  +nq+++ a + ++
  EEA22411.1  89 EYATPVLVGNS--TLLLDFDTGSSELWVFINETK---GRGSHNTYDHRTGTLF--PNATWHVTYGDYsYAKGIVYWDTVNIGGVIAPNQTVEAALQVSE 180
                 69999***987..9****************9998...789*******999988..789*********999***************************** PP

                 HHHTTSSSSEEEE-S-GGGSCGG...SCCHHHHHHHTTSSSSSEEEEEE-STTSSEEEEEESSEEGGGEEEEEEEEEESS.TSSTEEEEEEEEETTEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxx RF
         Asp  99 stflaakfdGiLGlgfkeisvee...atpvfdnlvsqglikepvfsvylnreeeeggeivfGgvDeskykGsltyvpvts.kgywqielesvtvggktv 193
                 s++ + ++dG++Gl+f++i++ +   ++++f n+++   +++pvf+v l   +++ g++ fG vD+ k+kG+l+y pv + +g+w++  +++ + +  +
  EEA22411.1 181 SFIRDLNNDGLVGLAFPNINMISpgpQNTFFANVMDT--LAKPVFAVTLK--HQAPGSYDFGFVDKDKFKGELIYKPVRNeTGFWTFMNDGFCIVKCGL 275
                 ********************9998889999***9987..9*********5..9**************************97899******998877665 PP

                 .EEEEEEEEEEETTCSSEEEEHHHHHHHHHHHTTEEEETT.CEEEEETTGGGGSEEEEEEETTEEEEEEGGGGEEEESSSTTSEEEESEEECCTSSSEE CS
                 .xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp 194 .lcssgcqailDtGTsllalptsivekiakaigakksese.geyvvdCdslsslpdisftiggakitvpvselvlkeeeseesqCilglvseeegdlwi 290
                   + + ++ i+DtGTsll+l+++iv ++ + ++++  + + g ++++C+s  +lp + +++++   +vp + + + +   ++++C+ g++s+++ +l+i
  EEA22411.1 276 tPTGRPFRGIVDTGTSLLILDDDIVMAYYRYVSTSRFSPMwGGVIFNCNS--KLPAFIVKVDDYLARVPGNLIRYASL--GDGTCFGGIQSNHGLPLNI 370
                 3788899*************************999866543999*****7..*****************987777666..4589*************** PP

                 EEHHHHTTEEEEEE.TTTTEEEEEE CS
                 xxxxxxxxxxxxxx.xxxxxxxxxx RF
         Asp 291 LGdvFlrsayvvfd.ldnnrvglAe 314
                 LGdvFl+s + vf    n  +glA+
  EEA22411.1 371 LGDVFLKSQFAVFVgKPNPMIGLAA 395
                 ************9646788899986 PP

>> TAXi_N  Xylanase inhibitor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.9   0.0    0.0011       6.7       1      28 [.      90     115 ..      90     140 .. 0.79
   2 !    8.2   0.0   0.00046       2.8      81     152 ..     141     208 ..     130     238 .. 0.74
   3 ?   -1.4   0.0       0.4   2.4e+03      11      26 ..     279     294 ..     270     302 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0011
      TAXi_N   1 YlvsisiGtppqplklvvDtGsdltWvq 28 
                 Y + + +G+   +l+l++DtGs+ +Wv 
  EEA22411.1  90 YATPVLVGNS--TLLLDFDTGSSELWVF 115
                 6677777876..899***********95 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.00046
      TAXi_N  81 yeisygadgssssGvlatdtltlsstdgksvkvpnlvfGCgksnlgglaa..gadGilGLGrgklSlvsqlask 152
                  +++yg d s+++G +  dt+ +     ++v  pn ++  + + ++++ +  + dG++GL++ ++ ++s   ++
  EEA22411.1 141 WHVTYG-DYSYAKGIVYWDTVNI-----GGVIAPNQTVEAALQVSESFIRdlNNDGLVGLAFPNINMISPGPQN 208
                 578997.999*************.....44445544444444444444443447**********9999866555 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.4
      TAXi_N  11 pqplklvvDtGsdltW 26 
                 ++p+  +vDtG +l+ 
  EEA22411.1 279 GRPFRGIVDTGTSLLI 294
                 688999*****99975 PP

>> Asp_protease_2  Aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.1     0.016        97       2      33 ..      93     124 ..      92     196 .. 0.60
   2 ?    8.5   0.0   0.00053       3.2       7      30 ..     279     302 ..     274     318 .. 0.87

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.016
  Asp_protease_2   2 pvtinGkpvrfllDTGasttlispelaeklgl 33 
                     pv +++ ++ + +DTG+s + +     +  g 
      EEA22411.1  93 PVLVGNSTLLLDFDTGSSELWVFINETKGRGS 124
                     67788889999999999987766555554444 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00053
  Asp_protease_2   7 GkpvrfllDTGasttlispelaek 30 
                     G+p+r ++DTG s ++++++ +++
      EEA22411.1 279 GRPFRGIVDTGTSLLILDDDIVMA 302
                     89****************998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       345  (0.0192426); expected 358.6 (0.02)
Passed bias filter:                      318  (0.0177366); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.67u 0.36s 00:00:01.03 Elapsed: 00:00:00.58
# Mc/sec: 2067.97
//
Query:       EEA22412.1  [L=274]
Description: hypothetical protein PMAA_090420 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.2e-08   32.6   0.0    1.2e-07   31.9   0.0    1.3  1  APH             Phosphotransferase enzyme family
  ------ inclusion threshold ------
      0.015   14.9   0.4       0.32   10.6   0.0    2.6  3  Choline_kinase  Choline/ethanolamine kinase
      0.085   12.0   0.5       0.13   11.4   0.5    1.2  1  Rota_NSP3       Rotavirus non-structural protein NSP3
       0.13   12.0   0.1       0.35   10.6   0.1    1.7  1  TFA2_Winged_2   TFA2 Winged helix domain 2


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.9   0.0   2.6e-11   1.2e-07      46     181 ..       3     198 ..       1     206 [. 0.65

  Alignments for each domain:
  == domain 1  score: 31.9 bits;  conditional E-value: 2.6e-11
                 HHHHTT-.B--B-CTTB.S-EEETTEEEEEEE----EE-SS...HHHHHHHHHHHHHHHHHHC.................................... CS
         APH  46 lLakagv.pvPevlagd.tddeeigllfalieyvpgrsllr...klsaaqlpellealgefla.................................... 103
                 + +k+   pvP ++ +d t ++ ig++f l+e+ pg s+++   kls++ + +++++l ++l                                     
  EEA22412.1   3 WARKHTHiPVPGIVRYDaTENNLIGHEFTLLERAPGVSVDQiydKLSMETKTNMVRQLTDYLIelylhpwkdgyvggltlhgngesvcgppideffwqv 101
                 55655555*******************************************************888888888888888555555555555555555555 PP

                 ..........CHHCH.-STTTB-.........SHHCHTCCHH....HHHHCHHHCCCGCCTCC...HHHHHHHHHHHHHHHH--S....SS-EEEE-SS CS
         APH 104 ..........alhqvdpaalpla.........dflaqdlell....rqlesatarllaselld...lleeleeqvlaalaallpg....elptvllHgD 172
                           ++h++                 +f+   +++     r++++     ++++l++    + +l + ++ +l++ + +     +  v+ H D
  EEA22412.1 102 pdlekywpspEMHEI-------LdminpipveGFTSYVAFNVgcleRYIHAI---NVHPLLEPyrdTVPRLQS-LIVTLEQPAFKdqlnRVVYVFAHKD 189
                 555555555544444.......033333333344433333112223555555...333333333333444444.4444444444444446889****** PP

                 -SGGGEEEC CS
         APH 173 lhpgNllvd 181
                 lh+gN++ +
  EEA22412.1 190 LHLGNIISE 198
                 ******988 PP

>> Choline_kinase  Choline/ethanolamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.0     0.043   1.9e+02      39      57 ..     130     148 ..     126     152 .. 0.84
   2 ?   10.6   0.0   7.1e-05      0.32     130     164 ..     158     202 ..     149     216 .. 0.68
   3 ?   -1.3   0.1      0.31   1.4e+03     118     139 ..     222     243 ..     203     252 .. 0.74

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.043
                     EEEEETTEEEEE--TCEE- CS
  Choline_kinase  39 lygifenGrieefiesrtl 57 
                      y+ f+ G++e++i++ ++
      EEA22412.1 130 SYVAFNVGCLERYIHAINV 148
                     6899**********99765 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 7.1e-05
                     HHHTHHHHHHCHGG-..........EEEE-S--SGGGEEE.-CTT CS
  Choline_kinase 130 elekleklleelesp..........vvfcHnDlqegNillnkeek 164
                     ++ +l++l+  le+p           vf+H Dl  gNi+ +++ +
      EEA22412.1 158 TVPRLQSLIVTLEQPafkdqlnrvvYVFAHKDLHLGNIISEDKAE 202
                     555555555433333333333444589************966554 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.31
                     CHCCCTHHHHHHHHHTHHHHHH CS
  Choline_kinase 118 qlklinledlekelekleklle 139
                     +l+++++++l++ ++++ + + 
      EEA22412.1 222 MLEEMKMNELQESMQNVVNQIR 243
                     5677888888888887766654 PP

>> Rota_NSP3  Rotavirus non-structural protein NSP3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.5   2.9e-05      0.13     163     204 ..     200     243 ..     188     255 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 2.9e-05
   Rota_NSP3 163 kskieeleqiidal..ekykdivldldkmneevkldqnsisyns 204
                 k+   ++e  ++ +  ek+  ++l+  kmne  ++ qn++ + +
  EEA22412.1 200 KAEQTQMEELFEKVclEKGPGWMLEEMKMNELQESMQNVVNQIR 243
                 5566688999997666***********************98865 PP

>> TFA2_Winged_2  TFA2 Winged helix domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.1   7.8e-05      0.35      17      37 ..     224     244 ..     205     251 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 7.8e-05
  TFA2_Winged_2  17 eGikvkdLkdswpdveealee 37 
                    e +k+++L++s+ +v++ ++e
     EEA22412.1 224 EEMKMNELQESMQNVVNQIRE 244
                    569***************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (274 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       777  (0.0433376); expected 358.6 (0.02)
Passed bias filter:                      590  (0.0329076); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.67u 0.37s 00:00:01.04 Elapsed: 00:00:00.57
# Mc/sec: 1459.79
//
Query:       EEA22413.1  [L=747]
Description: hypothetical protein PMAA_090430 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    0.00026   21.6   0.0      0.001   19.7   0.0    2.0  2  VWA_2       von Willebrand factor type A domain
  ------ inclusion threshold ------
      0.068   12.9   0.0       0.15   11.8   0.0    1.5  1  ATP_bind_3  PP-loop family


Domain annotation for each model (and alignments):
>> VWA_2  von Willebrand factor type A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0      0.94   8.4e+03      58      88 ..       2      31 ..       2      55 .. 0.71
   2 !   19.7   0.0   1.2e-07     0.001       1      90 [.     513     621 ..     513     632 .. 0.83

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.94
       VWA_2 58 dkakilnalrnleakgggtnlaaaLqlarka 88
                +++++ +alr+l +   +  l++ + +ar +
  EEA22413.1  2 NQQRFVSALRELLPL-SDNELEQVILYARGL 31
                578888999999987.666677666666644 PP

  == domain 2  score: 19.7 bits;  conditional E-value: 1.2e-07
       VWA_2   1 lvfvlDtSgSmrngdy................gptrleaakdaveallksl......pgdrvglvtfsdgpevlipltkdkakilnalrnleakgggtn 77 
                 ++++lD+SgSm+ + +                +p++ + a+++++++ +++      + d + lvtf++++e   + ++  + +++  rn++  gg t+
  EEA22413.1 513 TMILLDVSGSMNFDPVrpiyeqylitryvrasQPKNKDVARSIIRRFTEAIshgdqhHVDGYDLVTFANEAEYMGTINQ--RNFDEVWRNITF-GGRTR 608
                 79*********99855789999*********99****************886555423449999999999998777765..889999999997.69999 PP

       VWA_2  78 laaaLqlarkalk 90 
                 + a+ q+++++  
  EEA22413.1 609 VMAGWQQVKELHF 621
                 9999999988654 PP

>> ATP_bind_3  PP-loop family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   1.6e-05      0.15      73     136 ..      81     145 ..      42     150 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 1.6e-05
                 TSTCCCHHHHHHHHHHHHCHHCCT.CEEE---BHHHHHHHHHHHHCCT--C.CHHH-S-SEEEET CS
  ATP_bind_3  73 gknleeaARelRYevlkealkkegievlllAhhadDqaEtfllrlargsgl.aglagikeaseia 136
                 +   +++A    Y+ ++      gi+  ++Ahh +D +E   +r + ++++ + l+ ++++++i+
  EEA22413.1  81 KMRHDTEAHPPPYATISGSQTVRGINQYAIAHHTNDLIEASKIRAQDEQEMiQLLQRVQQEHRIY 145
                 555666777777889999999999******************99988877635555566666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (747 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       593  (0.0330749); expected 358.6 (0.02)
Passed bias filter:                      494  (0.0275531); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.81u 0.33s 00:00:01.14 Elapsed: 00:00:00.54
# Mc/sec: 4135.13
//
Query:       EEA22414.1  [L=121]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.31    9.8   0.6       0.34    9.7   0.6    1.1  1  LEF-4     Late expression factor 4 (LEF-4)


Domain annotation for each model (and alignments):
>> LEF-4  Late expression factor 4 (LEF-4)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.6   1.9e-05      0.34     316     344 ..      22      50 ..      13      72 .. 0.82

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 1.9e-05
       LEF-4 316 yitDvlsvfkykYdnrtqYevnaslsvDv 344
                 +   v +v+ky Y+n+t Y+v +  s D+
  EEA22414.1  22 FTNGVYQVYKYYYQNMTGYRVGTAPSTDL 50 
                 556799**************877666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (121 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       339  (0.0189079); expected 358.6 (0.02)
Passed bias filter:                      254  (0.014167); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.30s 00:00:00.83 Elapsed: 00:00:00.51
# Mc/sec: 715.45
//
Query:       EEA22415.1  [L=653]
Description: cytosolic phospholipase A2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.5e-23   80.7   0.0    1.8e-22   79.4   0.0    1.5  1  PLA2_B    Lysophospholipase catalytic domain


Domain annotation for each model (and alignments):
>> PLA2_B  Lysophospholipase catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.4   0.0     1e-26   1.8e-22       1     336 [.     146     512 ..     146     520 .. 0.84

  Alignments for each domain:
  == domain 1  score: 79.4 bits;  conditional E-value: 1e-26
      PLA2_B   1 iaiavSGGGyramltgaGvlkAldsRtdnatglgGlLqsatYlaGlsGgsWlvgslavNnftsvqelskkkeddsvweleksilnpeglelvknikryd 99 
                 i+  +SGGGyram++  G +  +          +Gl +  tY+aG+sG  W ++  ++   +++++++++   +s  +  +++  p+  +++++i+   
  EEA22415.1 146 IGFGGSGGGYRAMIGYIGYMTEMK--------NAGLWDLITYVAGVSGTCWSIAAYYTFADATIEHIVDH--FKSRLSPYHPLSDPAIRTTLTSINGPY 234
                 67789******************9........79**********************99999********5..456777889999998888888888766 PP

      PLA2_B 100 eivdevekKkdagfnvsltDiwGral.seklve..aeeggvnl.........tlsslkdaekfqeaemplPiivadgrk.................... 166
                 +    +  K+ ++  v l D++     ++ +++  +e+g v           ++s+ +  +++ e++ p+Pi++a   +                    
  EEA22415.1 235 NTLGPLILKQISNLHVVLMDLYSVFTtGYLFLHhsQESGSVRHkpnadrgwwKWSNAQ--KWLTEGQEPFPIMTAIRHErpwkdwvdkehpfkdenpls 331
                 89999999**************986516777764333333322111122222577666..9*************9888789999********9999887 PP

      PLA2_B 167 .pgetvinlNatvfEfsPyelgswdaklnsFvpveylGtklsnGtvvkkgkcvagfdnaGflmgtsstlFnevlleinsts...mlesllkellkkllk 261
                  +  + +++  ++fE++Pye+g    +l+s+vp+  +G  ++ G+++ +  + +     G+ +++ +   +  l +i+ +     l + +++l+ k+ +
  EEA22415.1 332 kEHAETVDAWYQWFEMTPYEIG--CDELESWVPTWGFGRPFDEGKSTMQLPEQSLALLLGLCTSAPAGPLDAYLATIKRNLpsgSLGNAVHDLALKITH 428
                 766677788899**********..899********************************************9999998887666677788888888888 PP

      PLA2_B 262 dlsedsedisqyapnpfkdaeeenqnatq...........sivesktLdlvdggedgqniplvpllqkerevdvifaldnsadtee 336
                 +  +++  + q +  p + ++e n                 i++s+ ++l+d g d+ n p   ll++erevdvi+ +d+s+d+++
  EEA22415.1 429 MWGKQKTKVFQQH-HPLHACNEHNFMFHMtsvpkgearppGIENSPRIHLLDSGLDN-NCPTYVLLRPEREVDVIIHMDASSDVHK 512
                 8888888887776.677777755544333457889999999*************995.9************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (653 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       746  (0.0416086); expected 358.6 (0.02)
Passed bias filter:                      554  (0.0308997); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.81u 0.38s 00:00:01.19 Elapsed: 00:00:00.56
# Mc/sec: 3496.56
//
Query:       EEA22416.1  [L=1206]
Description: DUF455 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.8e-33  114.2   0.4    1.2e-32  112.9   0.4    1.7  1  2_5_RNA_ligase2  2'-5' RNA ligase superfamily
    1.8e-27   95.9   0.0      4e-27   94.8   0.0    1.5  2  PAP_central      Poly(A) polymerase central domain
      1e-19   71.0   1.2    2.9e-19   69.6   0.7    2.1  2  MJ1316           MJ1316 RNA cyclic group end recognition doma
      9e-06   25.9   0.0    5.4e-05   23.4   0.0    2.3  2  NTP_transf_2     Nucleotidyltransferase domain
    1.1e-05   25.1   0.0    5.5e-05   22.8   0.0    2.1  1  Exo_endo_phos    Endonuclease/Exonuclease/phosphatase family
    2.3e-05   24.5   1.3       0.16   12.1   0.1    3.0  2  LigT_PEase       LigT like Phosphoesterase
  ------ inclusion threshold ------
      0.044   13.5   0.0       0.17   11.7   0.0    1.9  1  Nrap_D2          Nrap protein PAP/OAS-like domain
      0.077   13.1   0.2        1.1    9.4   0.0    2.8  3  Polbeta          Polymerase beta, Nucleotidyltransferase
      0.091   12.6   0.4        3.3    7.6   0.0    3.5  4  Exo_endo_phos_2  Endonuclease-reverse transcriptase


Domain annotation for each model (and alignments):
>> 2_5_RNA_ligase2  2'-5' RNA ligase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.9   0.4     6e-36   1.2e-32       1     150 [.      24     173 ..      24     175 .. 0.95

  Alignments for each domain:
  == domain 1  score: 112.9 bits;  conditional E-value: 6e-36
  2_5_RNA_ligase2   1 pppslaapiealrrslydkayprwppHitLlypfvededladlaellsrlak..etepfevrldgfgvFehkks.vvylsv..sdsealqalra 89 
                      pp++ +++i++lr +lydkay++wppHi+L+ypfv +e+++++ael++ ++    t pf ++ld++g+F+hk + +vy     + +e+++ +r+
       EEA22416.1  24 PPAHFSQEINRLR-ALYDKAYEKWPPHINLIYPFVNPETWPHVAELVRSVLVkhKTGPFLFELDKAGFFTHKRHrTVYSTSsgKCCEEVKLIRR 116
                      89999********.*************************************8335556*************9999******9999********* PP

  2_5_RNA_ligase2  90 allealpeagdkedsgeftPHlTiaqsadstsa..aelleklaqalpplefevdevallrrdg 150
                       +l+al++ +       f+PHlTi+qs+++ ++  ++l++k+ ++ p +e++v+e+ +l+r++
       EEA22416.1 117 HVLSALGQVD-----THFQPHLTIGQSDAHDESglEFLISKV-NLIPRVEWQVSEIVILKRER 173
                      *********8.....79**************99*********.******************97 PP

>> PAP_central  Poly(A) polymerase central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.0       2.5     5e+03     162     186 ..     160     189 ..     149     223 .. 0.68
   2 !   94.8   0.0     2e-30     4e-27      22     242 ..     595     901 ..     583     907 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 2.5
                  xxxxxxxxxxxxxxxxx.xx....xxxxxx RF
  PAP_central 162 kWkwpqpvlLkeieeke.ep....lrvWdp 186
                  +W+  + v+Lk+ +++  ++    +rvW +
   EEA22416.1 160 EWQVSEIVILKRERTTAfSStvnhMRVWGN 189
                  577777777777766443223344557754 PP

  == domain 2  score: 94.8 bits;  conditional E-value: 2e-30
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............................................................. RF
  PAP_central  22 LieeLkeqnlfeseeetkkreevlekleklvkefvkk............................................................. 58 
                  + + L+++++  se e ++r++++e +++ vk+                                                                 
   EEA22416.1 595 FNTILHDFDMLPSEVEIAHRQQMFELIRSAVKQQAIGtsvetrlnisfvvvpvgsyasgvwdpssdidclvigsispktfmalmvqklrrpewqeihi 692
                  567899999*******************99999877789*********************************************************** PP

                  ...............................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  PAP_central  59 ...............................lkevpedldlkddslLknldekevrslnGvRvtdeilrlvpnketFrlaLraiklWAkrraiysnvl 125
                                                 +++ p+ l+l  ++   +l  +++  ln  R  + + r++p+ +tFr+a r+ik WAk r+iys  l
   EEA22416.1 693 lrkvkatsgtmleiqaggvrfdlqycaatsvTDSWPKALTLPSSDPTFDLPMQSLLKLNSHRDLEYLQRTIPDLATFRKAYRFIKAWAKFRGIYSSKL 790
                  ******************************9999**************************************************************** PP

                  xxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  PAP_central 126 gflgGvawAllvariCqlyPnaaa....stlvskfFlvlskWkwpqpvlLkeieekeeplrvWdpkvnksdrahlmpiitpaypsmnstynvsrstle 219
                  g+lgG+   ll ar+C+l  + a     s ++s fF  +++++w++ ++ +++  +        pk +++ + + m i++   p++n ++  + s+ +
   EEA22416.1 791 GYLGGIHITLLLARVCKLSFREAGatsvSDIISDFFFYYENFDWKNDMVYETTFYTG------TPK-YHRLSREPMVILSIHPPKVNVAHASTVSSVH 881
                  ******************76655412226799**************99888776633......687.7888889************************ PP

                  xxxxxxxxxxxxxxxxxxxxxxx RF
  PAP_central 220 vlkeelkrgleiteeiesgkakw 242
                   l++e+kr++++++e+ ++   w
   EEA22416.1 882 TLEQEFKRAAQLISEVGAT---W 901
                  ************9998653...4 PP

>> MJ1316  MJ1316 RNA cyclic group end recognition domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0         9   1.8e+04      13      28 ..     655     670 ..     654     690 .. 0.76
   2 !   69.6   0.7   1.5e-22   2.9e-19       2      76 .]    1120    1189 ..    1119    1189 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 9
      MJ1316  13 Wdkeldkskfvvgyld 28 
                 Wd++ d +  v+g + 
  EEA22416.1 655 WDPSSDIDCLVIGSIS 670
                 9*99999999999765 PP

  == domain 2  score: 69.6 bits;  conditional E-value: 1.5e-22
      MJ1316    2 rtaqdvlnRirWdkeldkskfvvgyldRfkgikevpleeiswiedflleeeegelaIPlHRiryikr..kgevvWdR 76  
                  r+a d+lnR+rWd+++d+s++vvgy+dRf g ke+p++++++++    +e     +IP+HR+ y+kr  +g  vWdR
  EEA22416.1 1120 RPAGDILNRLRWDASFDSSEYVVGYIDRFVGEKEMPIDRWKSEQT---HE----EFIPMHRVSYFKRksDGVRVWDR 1189
                  7899**********************************7766444...44....46***********55599****9 PP

>> NTP_transf_2  Nucleotidyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       4.7   9.4e+03      58      87 ..     579     608 ..     565     613 .. 0.74
   2 !   23.4   0.0   2.7e-08   5.4e-05      15      43 ..     642     670 ..     630     694 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 4.7
                   HHCCCEEECTTEEEEEECEEECCC.CTEEEE CS
  NTP_transf_2  58 eiikfleellglevdlvtrekled.pllvks 87 
                    i++++ + + l  d++++++l+d ++l+++
    EEA22416.1 579 AIPFKTGP-RTLASDIHFNTILHDfDMLPSE 608
                   56667777.7788899999999987555544 PP

  == domain 2  score: 23.4 bits;  conditional E-value: 2.7e-08
                   SEEEEEHHHHCTTSCTTSSEEEEEEESTT CS
  NTP_transf_2  15 akvvlfGSyarGtalkgSDiDllvvlpee 43 
                     vv +GSya G + + SDiD+lv+++ +
    EEA22416.1 642 FVVVPVGSYASGVWDPSSDIDCLVIGSIS 670
                   56899*******************98755 PP

>> Exo_endo_phos  Endonuclease/Exonuclease/phosphatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8   0.0   2.8e-08   5.5e-05       2     206 ..     260     529 ..     259     555 .. 0.54

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 2.8e-08
                    EEEESTG.......CHHHHTHHHHHHHHHHHHHHCTT.SEEEEEEEBSCTCHHHHHHHHHTTCEEEEECCH......................... CS
                    xxxxxxx.......xxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......................... RF
  Exo_endo_phos   2 twNvngq.......aspalgssrrsdrladlltayda.DvlgLQEvdddelsriplllalggflgasstsp......................... 64 
                    ++Nv+         ++        s  l +ll  +   D+l LQEv d+ ls++++  + +  +++ss++p                         
     EEA22416.1 260 SYNVLAYtdqhssiER-------YSVILSNLLDGSSTaDILVLQEVSDSFLSFLLQSDKIRVRYTFSSHGPpeqrdigplpslrnivvlgrwrfrw 348
                    5677776655333333.......477777777666335***************9999987555555555445666666666666666666666666 PP

                    ...........................................ECSSSTTSSEEEEEECSTEEEEEEEEEEETSSSSGCEEEEEEEEEEEEEEECC CS
                    ...........................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Exo_endo_phos  65 ...........................................tgggggggnggavlsrfpltslfrrtfiefndlvaalrreplaakleqlnias 117
                                                                    +++  + +++ +                                    
     EEA22416.1 349 ewlkfekphkgsiilqledigtlrgtrflplivagvhltcgltDASISAKHAQVRTVIEHLQ---------------------------------- 410
                    66666666666555555555555555555554444444433333333333333322222222.................................. PP

                    CHHGHHHHHHHHHHHHHHHHHHHHHTTSEEEEEEE-SSSTSGGGBSCGHHHHHHCTTTH....HSSCESCETTTTTTTTTTTEB-B.......... CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxx.......... RF
  Exo_endo_phos 118 hrdhdlvrdlqllalllqvealnadrgapvivaGDfNarpsdddsrvlrtrglalapap....vglyllgggptptyvtraggsrl.......... 199
                                          ++ r++ +i+aGDfN ++s++   v  +r   +a  +    +                    rl          
     EEA22416.1 411 ----------------------TQYRDHNWIIAGDFNIPSSSRTIDVALKRNSITARSAatllG------------------LDRLfaeskltdcy 466
                    ......................2336677999***********999988888777664422220..................22222222222222 PP

                    ........................................................EEEEEEC CS
                    ........................................................xxxxxxx RF
  Exo_endo_phos 200 ........................................................Drilasp 206
                                                                            Dri+ ++
     EEA22416.1 467 fesritgtysaeetmllaedlrtiyegeegatydpvknglaaniskksfhsrpqryDRIYTKG 529
                    222223333333333355555555555555555555555555556666666666666666665 PP

>> LigT_PEase  LigT like Phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.1   0.2   0.00037      0.73       2      87 .]      24     100 ..      22     100 .. 0.79
   2 !   12.1   0.1   8.2e-05      0.16      19      79 ..     115     171 ..     109     176 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00037
                 E-CHHHHHHHHHHHHHHHHHHCCTTEEETSGGGSEEEEEEEEEES..HHHHHHHHHHHHHHHHTSBEEEEEEEEEEEEEECCSCCEEE CS
  LigT_PEase   2 gppeeiaeelarlaaeleralaklglkpvrpfnpHiTLaflgevd..eekvpellealaeiasgaepfelkvdgvglfpsrlrprviy 87 
                 + p+++++e++rl+a +++a+        ++ +pHi L  ++  +   + v+el++++  + +++ pf +++d++g f  ++r+r++y
  EEA22416.1  24 P-PAHFSQEINRLRALYDKAY--------EKWPPHINLIYPFVNPetWPHVAELVRSVL-VKHKTGPFLFELDKAGFFT-HKRHRTVY 100
                 4.99999***********555........6777********844445566677777776.678999************6.55787776 PP

  == domain 2  score: 12.1 bits;  conditional E-value: 8.2e-05
                 HHHHCCTTEEETSGGGSEEEEEEEEEESHHHHHHHHHHHHHHHHTSBEEEEEEEEEEEEEE CS
  LigT_PEase  19 eralaklglkpvrpfnpHiTLaflgevdeekvpellealaeiasgaepfelkvdgvglfps 79 
                 +r++ ++ ++++  f+pH+T++   + de+ ++ l+++++ i    +++e++v++++  + 
  EEA22416.1 115 RRHVLSALGQVDTHFQPHLTIGQSDAHDESGLEFLISKVNLI----PRVEWQVSEIVILKR 171
                 55555566677799*************************977....6889*****998774 PP

>> Nrap_D2  Nrap protein PAP/OAS-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   8.3e-05      0.17       2     139 ..     769     896 ..     768     901 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 8.3e-05
                 HHHHHHHHHHHHHHTT--SS--TS-S-SHHHHHHHHHHHTSBBSTTS-BSS-TT--HHHHHHHHHHHHHHS--SS-EEEE-------BEEES-.--SS. CS
     Nrap_D2   2 fkdAclLlkvWlrqRgfgssirkaggfggfewamllalllqgggkkgrkklskslssyqlfkavlqfLastdltkkpiflgaskseeskkeseeefska 100
                 f++A   +k W++ Rg+ s  +k+g +gg  +++lla + +        +     s   ++  ++ +  + d++++ ++ ++  +    +++ + +s+ 
  EEA22416.1 769 FRKAYRFIKAWAKFRGIYS--SKLGYLGGIHITLLLARVCKL-----SFREAGATSVSDIISDFFFYYENFDWKNDMVYETTFYT---GTPKYHRLSRE 857
                 999***************4..4579***************33.....23333334555788888888888888555555422222...22333334444 PP

                 ..--EEETTT--BTTTT--HHHHHHHHHHHHHHHHHHT- CS
     Nrap_D2 101 fepvlvdpsgklNllakmtassydlLqqeAketlelLdd 139
                   ++l  +  k+N+++  t+ss+++L qe k++ +l+++
  EEA22416.1 858 PMVILSIHPPKVNVAHASTVSSVHTLEQEFKRAAQLISE 896
                 5677777889*******************9999998865 PP

>> Polbeta  Polymerase beta, Nucleotidyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.1       0.7   1.4e+03      35      83 ..     263     309 ..     250     313 .. 0.78
   2 ?    9.4   0.0   0.00053       1.1       9      42 ..     636     670 ..     628     697 .. 0.79
   3 ?   -3.3   0.0         5   9.9e+03      46      82 ..    1029    1065 ..    1021    1069 .. 0.71

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.7
                 EEEEESS---HHHHHHHHHHHHHH.SSSEEEEEETTTS-HHHHHHHHHS CS
     Polbeta  35 lavllkekldleeelelaaelediklgkkvDlvdlneapplllyeilke 83 
                 +  +++++ ++e++  + ++l d   +   D+++l+e++  +l   l++
  EEA22416.1 263 VLAYTDQHSSIERYSVILSNLLDG--SSTADILVLQEVSDSFLSFLLQS 309
                 556777778999999999999998..5899******9888888776665 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.00053
                 HHHHHHSTTE.EEEEE-S------EEEEEEEESS- CS
     Polbeta   9 kekeielayl.FGSrakgkareeSDiDlavllkek 42 
                 ++ +i+++++  GS+a+g   ++SDiD  v+ + +
  EEA22416.1 636 TRLNISFVVVpVGSYASGVWDPSSDIDCLVIGSIS 670
                 555777777756***************99987655 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 5
                  HHHHHHHHHHHHH.SSSEEEEEETTTS-HHHHHHHHH CS
     Polbeta   46 eeelelaaelediklgkkvDlvdlneapplllyeilk 82  
                  e++++ +  + d++l k+ Dl++l+  +++  +++ +
  EEA22416.1 1029 ETYFDKSCSWVDVSLAKRNDLQNLHLDKSDWSHNAAN 1065
                  5566666667777788999999999666777777766 PP

>> Exo_endo_phos_2  Endonuclease-reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   0.0    0.0016       3.3      15      43 ..     400     428 ..     391     444 .. 0.82
   2 ?   -2.4   0.0         2     4e+03     106     118 ..     546     558 ..     543     559 .. 0.80
   3 ?    0.3   0.0       0.3     6e+02      79     103 ..    1029    1057 ..     966    1073 .. 0.71
   4 ?   -2.1   0.0       1.7   3.4e+03      61      99 ..    1166    1202 ..    1155    1205 .. 0.74

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0016
  Exo_endo_phos_2  15 enlestlekllselkspkiiilGDfNakh 43 
                       ++ + +e+l ++ ++ + ii+GDfN ++
       EEA22416.1 400 AQVRTVIEHLQTQYRDHNWIIAGDFNIPS 428
                      55666777777777777*********987 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 2
  Exo_endo_phos_2 106 leeedlgSDHrpi 118
                      + e +lgSDH  i
       EEA22416.1 546 KREGQLGSDHWGI 558
                      567899****987 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.3
  Exo_endo_phos_2   79 ptfkssngsstiDltltsdnlals.....k 103 
                        t+ +++  s++D+ l++ n +++     +
       EEA22416.1 1029 ETYFDKS-CSWVDVSLAKRNDLQNlhldkS 1057
                       4554545.5999999999888887433321 PP

  == domain 4  score: -2.1 bits;  conditional E-value: 1.7
  Exo_endo_phos_2   61 iefleehslsllnllksgptfkssngsstiDltltsdnl 99  
                       +ef+  h +s+++++  g +++++++   iDl++ +  +
       EEA22416.1 1166 EEFIPMHRVSYFKRKSDGVRVWDREK--RIDLIFNTGVI 1202
                       67888888888888888888888665..89999987655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1206 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       465  (0.0259356); expected 358.6 (0.02)
Passed bias filter:                      403  (0.0224776); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.96u 0.37s 00:00:01.33 Elapsed: 00:00:00.58
# Mc/sec: 6227.65
//
Query:       EEA22417.1  [L=641]
Description: GMC oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.8e-42  145.1   0.0    3.9e-42  144.6   0.0    1.2  1  GMC_oxred_N     GMC oxidoreductase
    1.9e-35  122.5   0.0    3.4e-35  121.7   0.0    1.4  1  GMC_oxred_C     GMC oxidoreductase
    2.6e-06   26.8   0.5     0.0011   18.2   1.7    2.3  2  FAD_binding_2   FAD binding domain
    0.00013   21.7   0.0    0.00042   20.0   0.0    1.9  2  DAO             FAD dependent oxidoreductase
    0.00044   19.6   0.1      0.093   12.0   0.0    2.2  2  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
    0.00087   18.6   0.6     0.0016   17.8   0.3    1.5  2  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
     0.0011   19.2   0.2     0.0029   17.8   0.2    1.8  1  NAD_binding_8   NAD(P)-binding Rossmann-like domain
     0.0037   16.4   0.0     0.0058   15.7   0.0    1.3  1  Lycopene_cycl   Lycopene cyclase protein
  ------ inclusion threshold ------
      0.021   13.5   1.2      0.036   12.8   1.2    1.3  1  HI0933_like     HI0933-like protein
      0.026   13.8   0.2      0.047   12.9   0.2    1.3  1  Thi4            Thi4 family
      0.057   13.9   0.0       0.25   11.8   0.0    2.0  2  NAD_binding_7   Putative NAD(P)-binding
      0.098   11.5   0.1       0.14   11.0   0.1    1.2  1  Trp_halogenase  Tryptophan halogenase
       0.13   11.4   0.9       0.21   10.8   0.9    1.2  1  FAD_binding_3   FAD binding domain
       0.24   12.0   1.1       0.47   11.0   1.1    1.4  1  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
       0.64    9.3   2.6          1    8.6   2.6    1.3  1  FAD_oxidored    FAD dependent oxidoreductase


Domain annotation for each model (and alignments):
>> GMC_oxred_N  GMC oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  144.6   0.0   3.3e-45   3.9e-42       1     295 [.      54     376 ..      54     377 .. 0.82

  Alignments for each domain:
  == domain 1  score: 144.6 bits;  conditional E-value: 3.3e-45
  GMC_oxred_N   1 vdelveggGsagsvvAaRLsedpstsvlvleaggreknrl..........imvlalalklidkklntayetepekalngrrlilpaGktlGGgsvvNw 88 
                  +d++++ggG ag ++A+RL++ + +sv v+eagg ++  +          + + +  l + +  +++ + t+p+  l +rrl  ++GktlGG+s+ N 
   EEA22417.1  54 FDYVIAGGGNAGLTIATRLAQTG-ASVAVIEAGGFYEVDNgnlsivpgyaTYFTGSDLDNYSPLVDWGFATTPQAPLGNRRLHYARGKTLGGSSARNY 150
                  69*****************9986.69********88777778875442222222222333334579******************************** PP

  GMC_oxred_N  89 sayiRtpaadldeWeeeaglegwssdevlpafkkvetaqale.............sdlhgvdgrlgvtekgkeesplnkallkaaeelGlpvprdlng 173
                  + y R++ + +++W++e   + + +d +lp+++k  +++ ++             + + ++ g+l+v +  +   p      +a  +++++  + +++
   EEA22417.1 151 MLYQRATVDSMQQWADEVDDQSYTWDAFLPYYQKFINYTPPDqtlytnssneqdpNAFNATGGPLKV-SFSNFVDPFGTWAQQAFIKANMSEIEGFDS 247
                  ************************************999999**********99999**********.666666665555555555555553344444 PP

  GMC_oxred_N 174 khqcGvcllgv.tc.rtgarqstarawLrpalerpn..leiltgakaekiilegrkkravGVeasdkkgt....vkrlvvaakevvvaaGalnsPqlL 263
                  ++  G+  + +     +  r   ++++L  a ++ +  l++ ++  a+ki+++  +k a+GV++s  +      ++++ +a+kev+++aGa++sPqlL
   EEA22417.1 248 GKLLGSAYATLtIDpSNAWRETPESSFLNYAFNA-GlpLTVYKSSLAQKILFD-SNKTAIGVQVSAAGFFgtpsINFTLTARKEVILSAGAFQSPQLL 343
                  4444444444434404555667788899999988.722578999********8.8999******99876556889*********************** PP

  GMC_oxred_N 264 qrSGlGkaehLkevgvdvvvdlp.vGknLqdHp 295
                  + SG+G+ ++L+ +++  + +l  vG+n+qdHp
   EEA22417.1 344 MISGIGPCAELAAFNIPCISNLTgVGQNMQDHP 376
                  ********************************9 PP

>> GMC_oxred_C  GMC oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.7   0.0   2.8e-38   3.4e-35       1     143 [.     490     628 ..     490     629 .. 0.92

  Alignments for each domain:
  == domain 1  score: 121.7 bits;  conditional E-value: 2.8e-38
                  ----EEEEESTT-TCCEEEEE--TT-SHHHHHHHHHHHHHHHHHCTSGGGTTEECCEECCCTTTTS.HCHHCHHCHHCHHHHH-EE-S--B-TT-B-S CS
  GMC_oxred_C   1 PesrGrvtlsssdptgaplidpnylsdprdlaalvealkaarkilaaaaldvleeeltpgaaeetsdaavesdealekfvkeavltsaHplGtcrMGa 98 
                  P srG+v+l+s+++t +p+idpn+l dp+dl+ +++ +k  r+i+   a      ++  ++ e  + ++ ++d ++++++ e+++t++H + tc+MG+
   EEA22417.1 490 PLSRGTVKLQSNSMTHPPIIDPNWLADPTDLDLAIQSFKRQREIWSILA----DLGVADKT-EAFPGSNYTTDSQIQQIIVESMTTVYHASATCKMGN 582
                  78**********************************************3....44444444.5555667888888*********************** PP

                  TCGC.BSB-TTSBBTT-CSEEE-SGGGSSS--SS-THHHHHHHHHH CS
  GMC_oxred_C  99 dpkd.sVVDsdlrvhgvdnLrVvDaSvfPsapganptltilalAek 143
                  + ++ +V+Dsd rv+gv+nLrVvDaS fP  p ++p++ ++alAek
   EEA22417.1 583 NGDPmAVLDSDARVYGVQNLRVVDASSFPFLPPGHPQALVYALAEK 628
                  *********************************************9 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   1.7   8.8e-07    0.0011       1      32 [.      55      86 ..      55      91 .. 0.94
   2 !    5.2   0.0    0.0077       9.2     147     204 ..     274     339 ..     119     362 .. 0.86

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 8.8e-07
                   SEEEE--SHHHHHHHHHHHHTTT-EEEEESSS CS
  FAD_binding_2  1 DviViGsGlAGLaAAleaaeaGlkvavvekeq 32
                   D ++ G+G AGL+ A+++a+ G++vav+e ++
     EEA22417.1 55 DYVIAGGGNAGLTIATRLAQTGASVAVIEAGG 86
                   789**************************875 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0077
                    HHHHHHTCT..EEEEESEEEEEEEECTT.EEEEEEEEET....TTTCEEEEEES.EEEE-----GG CS
  FAD_binding_2 147 lvesarkag..vdfqerteadeLivedg.rvtGavvenp....esgrevrirak.avvlatgGfgr 204
                    ++++a +ag  ++++ +  a++++ +++  + G+ v+      + + +++++a+  v+l +g+f+ 
     EEA22417.1 274 FLNYAFNAGlpLTVYKSSLAQKILFDSNkTAIGVQVSAAgffgTPSINFTLTARkEVILSAGAFQS 339
                    5667777777799************866699******99***999999****************97 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   0.0   3.5e-07   0.00042       1      49 [.      55     103 ..      55     218 .. 0.71
   2 ?   -2.2   0.0         2   2.3e+03     185     207 ..     317     339 ..     284     351 .. 0.62

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 3.5e-07
                 EEEEECTSHHHHHHHHHHHHTT..EEEEESSSSTTSSGGGSSEEEEESSSS CS
         DAO   1 dvviiGGGiiGlstAyeLarrg..VtllekgdiagsgaSgrnsgllhsglr 49 
                 d vi GGG +Gl++A  La+ g  V+++e+g  +  +   +n  ++ ++  
  EEA22417.1  55 DYVIAGGGNAGLTIATRLAQTGasVAVIEAG-GFY-EVDNGNLSIVPGYAT 103
                 89*******************9*********.766.777777777766443 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 2
                 ECT.EEEE.EEEE.EEE--GGGHHHH CS
         DAO 185 ttp.gend.aada.vVnaaGawsdll 207
                 t + +  + +a++ v+++aGa+  ++
  EEA22417.1 317 TPSiNF-TlTARKeVILSAGAF--QS 339
                 333333.1344667******99..34 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.0   7.8e-05     0.093       1      30 [.      57      85 ..      31     102 .. 0.73
   2 !    5.3   0.0    0.0085        10     126     147 ..     328     349 ..     294     360 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 7.8e-05
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEkg 30
                 +I G+G aGl++a+ l + g  ++ ++E g
   EEA22417.1 57 VIAGGGNAGLTIATRLAQTGA-SVAVIEAG 85
                 456666666666666666666.46666655 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0085
  Pyr_redox_3 126 kkviiAtGefdkPnklnipGee 147
                  k+vi+++G f+ P++l i+G  
   EEA22417.1 328 KEVILSAGAFQSPQLLMISGIG 349
                  57*****************987 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.3   1.3e-06    0.0016       1      33 [.      54      86 ..      54     111 .. 0.85
   2 ?   -3.4   0.0       3.6   4.3e+03      96     119 ..     322     348 ..     289     362 .. 0.69

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 1.3e-06
                 CSEEEE--SHHHHHHHHHHHHHTS-EEEEETTH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  1 kdvvviGgGpAGlaaaltlaqagakvtlveleg 33
                 +d+v+ GgG AGl+ a++laq ga v+++e++g
   EEA22417.1 54 FDYVIAGGGNAGLTIATRLAQTGASVAVIEAGG 86
                 589**************************7443 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 3.6
                  EEEEE.SEEEE---E..EE-BCTCTTC CS
                  xxxxx.xxxxxxxxx..xxxxxxxxxx RF
  Pyr_redox_2  96 ekiay.dklvlAtGs..sprdlgipGv 119
                  +++++ ++++l  G+  sp +l i G 
   EEA22417.1 322 FTLTArKEVILSAGAfqSPQLLMISGI 348
                  455555888899997667777788877 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.2   2.4e-06    0.0029       1      28 [.      58      85 ..      58     115 .. 0.91

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 2.4e-06
                   EE--SHHHHHHHHHHHCCTEEEEEE-SS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekr 28
                   I G+G +Gl++A +La+ g++v ++e++
     EEA22417.1 58 IAGGGNAGLTIATRLAQTGASVAVIEAG 85
                   67************************86 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   4.8e-06    0.0058       1      33 [.      55      85 ..      55     116 .. 0.95

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 4.8e-06
  Lycopene_cycl  1 DvvviGaGpAglslAarlteakpglkvvlieas 33
                   D v+ G+G Agl +A rl  a++g +v +iea+
     EEA22417.1 55 DYVIAGGGNAGLTIATRL--AQTGASVAVIEAG 85
                   789***************..***********98 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   1.2     3e-05     0.036       2      32 ..      55      85 ..      54      87 .. 0.94

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 3e-05
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SS CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVllleka 32
                 d ++ GgG AGl  A ++a++g++V+++e++
   EEA22417.1 55 DYVIAGGGNAGLTIATRLAQTGASVAVIEAG 85
                 789*************************986 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.2     4e-05     0.047      17      49 ..      53      84 ..      50      87 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 4e-05
                EEEEEEE--SHHHHHHHHHHHHCTTS-EEEEES CS
        Thi4 17 esDvvivGaGssGLtaayylakkpdlkvailer 49
                  D vi G+G +GLt a  la+  +  va++e+
  EEA22417.1 53 TFDYVIAGGGNAGLTIATRLAQT-GASVAVIEA 84
                5799*******************.*******96 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   0.00021      0.25      10      45 ..      56      91 ..      52     142 .. 0.70
   2 ?   -1.8   0.0       3.6   4.3e+03      64      92 ..     457     486 ..     428     493 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00021
  NAD_binding_7 10 vlvvGgGevAarkvrklleagakvtvvapevkeele 45
                    +++GgG+ +++ + +l+++ga v v+    ++e++
     EEA22417.1 56 YVIAGGGNAGLTIATRLAQTGASVAVIEAGGFYEVD 91
                   68************************9877544444 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 3.6
  NAD_binding_7  64 lviaatddrelneriaeaa.karrilvnva 92 
                    l +aa +  +ln++ a+ +   + + +nva
     EEA22417.1 457 LPVAAYNGYNLNKQTADPCdGHNYATLNVA 486
                    668999999999999999943355566666 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.1   0.00012      0.14       3      51 ..      57     103 ..      55     114 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00012
                     EEE--SHHHHHHHHHHHHHTTTSSEEEEEE-SSS---SS-E.E--THHHH CS
  Trp_halogenase   3 vivGGGtaGwlaAaalakalkgklevtlveseeigtvgvGe.atipsirk 51 
                     vi+GGG aG + A+ la+++   ++v ++e+  +  v  G  + +p   +
      EEA22417.1  57 VIAGGGNAGLTIATRLAQTG---ASVAVIEAGGFYEVDNGNlSIVPGYAT 103
                     9*****************99...89******9999999999888887666 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.9   0.00018      0.21       4      31 ..      56      83 ..      53      86 .. 0.92

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00018
                   EEEE--SHHHHHHHHHHHHTTHHEEEEE CS
  FAD_binding_3  4 VlIVGaGpaGlmlallLseaGvrvvlve 31
                    +I G+G aGl+ a+ L++ G +v ++e
     EEA22417.1 56 YVIAGGGNAGLTIATRLAQTGASVAVIE 83
                   579************************9 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   1.1    0.0004      0.47       3      30 ..      57      84 ..      55      87 .. 0.94

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.0004
                EEECSSHHHHHHHHHHHHTTSEEEEEES CS
   Pyr_redox  3 vvvGgGyiglElAgalaelgkkVtvver 30
                v+ GgG+ gl  A+ la+ g++V v+e+
  EEA22417.1 57 VIAGGGNAGLTIATRLAQTGASVAVIEA 84
                89************************97 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   2.6   0.00087         1       1      33 [.      55      87 ..      55      88 .. 0.94

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00087
  FAD_oxidored  1 DvvVvGGgpaGvaAAiaAaraGakvlLveergv 33
                  D v+ GGg aG++ A   a+ Ga+v+++e  g+
    EEA22417.1 55 DYVIAGGGNAGLTIATRLAQTGASVAVIEAGGF 87
                  669**************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (641 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       368  (0.0205254); expected 358.6 (0.02)
Passed bias filter:                      330  (0.0184059); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.60u 0.32s 00:00:00.92 Elapsed: 00:00:00.48
# Mc/sec: 4016.71
//
Query:       EEA22418.1  [L=282]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.066   12.7   2.5      0.092   12.3   2.5    1.3  1  LrgB             LrgB-like family
        4.9    7.1  13.2        7.3    6.5   0.7    2.2  2  ABC2_membrane_4  ABC-2 family transporter protein


Domain annotation for each model (and alignments):
>> LrgB  LrgB-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   2.5     1e-05     0.092      16     107 ..      81     188 ..      65     215 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1e-05
        LrgB  16 kkpllnPvlvaivliillllllgis................yetYkegakllsllLgpatVaLAvpLYkqrellkknllaillgllvgslvsllsavll 98 
                 +  +l  +lva ++ + ++ ++g +                  ++++g+ + +++L+ ++ +L vp+  ++++  ++ l i   +++g +v ++s++ +
  EEA22418.1  81 TLYFLAFLLVAFIIACPIVAVAGCHpvfyywdnnqpgscinEVEFYRGNGIANVILDFVIFCLPVPMTLRLNTTVRQKLIISGIVILGFFVCAVSIIRI 179
                 36788889999999999999999999999999999999988778999999**********************************************999 PP

        LrgB  99 akllglsee 107
                 + + g++++
  EEA22418.1 180 VAFNGFNPK 188
                 999888765 PP

>> ABC2_membrane_4  ABC-2 family transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   6.0    0.0027        24      96     160 ..      39     103 ..      36     110 .. 0.90
   2 ?    6.5   0.7   0.00081       7.3       7      65 ..     157     216 ..     155     225 .. 0.68

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0027
  ABC2_membrane_4  96 laKlivllllsvllmlvtflitvlfallsgfvgfsvklvlellkkclelgllvffavlpiialvl 160
                      + K+   ++ + +l++v +++t ++ l++ +  f v+  ++    +l + l+ f++ +pi+a++ 
       EEA22418.1  39 VVKFNKSFIAVQMLYFVDVVATKAAFLFLYYRIFGVNVWFRRTLYFLAFLLVAFIIACPIVAVAG 103
                      678888999999********9999999999999*******99999****************9975 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.00081
  ABC2_membrane_4   7 lKlkrskivwllvlaallvpllallyfnll..gktgldpaefyslsvfgftlllllplilg 65 
                      +Kl  s iv+l++++ ++  +  +++fn +  ++t++++ e  ++s+++  + ++ +++l+
       EEA22418.1 157 QKLIISGIVILGFFVCAVSII-RIVAFNGFnpKDTTWSTVETAMWSSIEQAVAIICMCLLT 216
                      566667778888887776544.444444331144667888999999998888888888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (282 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       750  (0.0418317); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.31s 00:00:00.81 Elapsed: 00:00:00.48
# Mc/sec: 1757.72
//
Query:       EEA22419.1  [L=252]
Description: superoxide dismutase [cu-zn], putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.6e-43  147.6   2.6    4.4e-43  146.9   2.6    1.3  1  Sod_Cu    Copper/zinc superoxide dismutase (SODC)


Domain annotation for each model (and alignments):
>> Sod_Cu  Copper/zinc superoxide dismutase (SODC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  146.9   2.6   2.4e-47   4.4e-43       5     142 .]      40     179 ..      37     179 .. 0.96

  Alignments for each domain:
  == domain 1  score: 146.9 bits;  conditional E-value: 2.4e-47
                 EEEEEEEEEEEECSTTSTCEEEEEEEECSS-STEEEEEEEESSTTTTTTTGGG-SB-STT-.CSSTTTTTCS-TTEEEEEEESTTSEEEEEEEEESC.B CS
      Sod_Cu   5 kgevsGtvtftqeeskesgsvevtvevkglppggkhgfHiHengdcsagfksagghfnptgkkhgapndeerhaGDLgnievdadgtakleittdklvs 103
                 +++v+G vtf q++   ++ ++++++++g +p+ k g+HiH  gd+++g++s+g hfnp++ +hgapnd++rh+GD+gn  +d++g++  +++ d+l++
  EEA22419.1  40 DSAVKGFVTFDQTD--VHSLTTISWNITGSDPNTKRGIHIHDRGDLTQGCTSTGSHFNPYNMTHGAPNDTTRHLGDMGNYMTDSQGNSVGNLQ-DSLIK 135
                 5789********88..45689******************************************************************999987.***** PP

                 CSTTTBCTTEEEEEESS---TT.....SCHHHTTSSSEEEEEEE CS
      Sod_Cu 104 lkgensilgralvihagaDdlg.....eskptgnagariacGvI 142
                 l+g+ si+gra+v+ha++Ddlg     es++tgnagar+acGvI
  EEA22419.1 136 LNGPLSIVGRAVVVHAQTDDLGrggnaESLKTGNAGARLACGVI 179
                 **999**************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (252 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       445  (0.0248201); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.42
# Mc/sec: 1796.83
//
Query:       EEA22420.1  [L=268]
Description: superoxide dismutase [cu-zn], putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-41  142.3   2.9    2.1e-41  141.4   2.9    1.4  1  Sod_Cu    Copper/zinc superoxide dismutase (SODC)


Domain annotation for each model (and alignments):
>> Sod_Cu  Copper/zinc superoxide dismutase (SODC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  141.4   2.9   1.2e-45   2.1e-41       5     140 ..      40     177 ..      37     178 .. 0.95

  Alignments for each domain:
  == domain 1  score: 141.4 bits;  conditional E-value: 1.2e-45
                 EEEEEEEEEEEECSTTSTCEEEEEEEECSS-STEEEEEEEESSTTTTTTTGGG-SB-STT-.CSSTTTTTCS-TTEEEEEEESTTSEEEEEEEEESC.B CS
      Sod_Cu   5 kgevsGtvtftqeeskesgsvevtvevkglppggkhgfHiHengdcsagfksagghfnptgkkhgapndeerhaGDLgnievdadgtakleittdklvs 103
                 +++v+G vtf q++   ++ ++++++++g +p+ k g+HiH  gd+++g++s+g hfnp++ +hgapnd++rh+GD+gn  +d++g++  +++ d+l++
  EEA22420.1  40 DSAVKGFVTFDQTD--VHSLTTISWNITGSDPNTKRGIHIHDRGDLTQGCTSTGSHFNPYNMTHGAPNDTTRHLGDMGNYMTDSQGNSVGNLQ-DSLIK 135
                 5789********88..45689******************************************************************999987.***** PP

                 CSTTTBCTTEEEEEESS---TT.....SCHHHTTSSSEEEEE CS
      Sod_Cu 104 lkgensilgralvihagaDdlg.....eskptgnagariacG 140
                 l+g+ si+gra+v+ha++Ddlg     es++tgnagar+acG
  EEA22420.1 136 LNGPLSIVGRAVVVHAQTDDLGrggnaESLKTGNAGARLACG 177
                 **999************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (268 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       499  (0.027832); expected 358.6 (0.02)
Passed bias filter:                      337  (0.0187964); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 1896.27
//
Query:       EEA22421.1  [L=135]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (135 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       215  (0.0119917); expected 358.6 (0.02)
Passed bias filter:                      197  (0.0109878); expected 358.6 (0.02)
Passed Vit filter:                        10  (0.000557756); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.30s 00:00:00.73 Elapsed: 00:00:00.47
# Mc/sec: 867.21
//
Query:       EEA22422.1  [L=156]
Description: hypothetical protein PMAA_090520 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.7e-06   26.3   6.5    8.7e-06   25.7   6.5    1.3  1  bZIP_1        bZIP transcription factor
     0.0032   17.5   4.4     0.0047   17.0   4.4    1.2  1  Cep57_CLD     Centrosome localisation domain of Cep57
     0.0093   16.2   7.1      0.011   16.0   7.1    1.2  1  ATG16         Autophagy protein 16 (ATG16)
  ------ inclusion threshold ------
      0.018   14.6   2.3      0.021   14.4   2.3    1.1  1  TMCO5         TMCO5 family
      0.019   15.4   4.2      0.023   15.2   4.2    1.2  1  Fez1          Fez1
      0.043   14.0   0.2      0.049   13.8   0.2    1.2  1  Spore_GerAC   Spore germination B3/ GerAC like, C-terminal
      0.044   12.8   2.6      0.058   12.4   2.6    1.1  1  ANTH          ANTH domain
      0.061   13.9   7.0      0.076   13.5   7.0    1.2  1  APG6_N        Apg6 coiled-coil region
       0.12   10.9   0.6       0.13   10.8   0.6    1.0  1  FapA          Flagellar Assembly Protein A
       0.17    9.8   1.5       0.21    9.5   1.5    1.1  1  Prominin      Prominin
       0.19   11.9   3.8       0.27   11.4   3.2    1.5  2  Fib_alpha     Fibrinogen alpha/beta chain family
       0.35   10.9   6.7       0.63   10.1   6.7    1.4  1  ABC_tran_Xtn  ABC transporter
       0.79    9.8   4.0          3    8.0   1.5    2.4  2  HisKA         His Kinase A (phospho-acceptor) domain


Domain annotation for each model (and alignments):
>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.7   6.5   6.3e-09   8.7e-06       8      62 ..      41      95 ..      35      97 .. 0.93

  Alignments for each domain:
  == domain 1  score: 25.7 bits;  conditional E-value: 6.3e-09
                XXX--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  8 krkqkNReaArrsRqRKqaeieeLerrvkaLekeNksLkseleelkkevekLksk 62
                kr+++ R a+r  R+RK ++ + Le++v  L +  ++  ++++el+ ++  L++ 
  EEA22422.1 41 KRREQVRKAQRTHRERKDQYLKTLESEVLRLRANEADFMKKIQELETHIFHLQEA 95
                9**********************************************99888766 PP

>> Cep57_CLD  Centrosome localisation domain of Cep57
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   4.4   3.4e-06    0.0047      97     151 ..      33      90 ..      13     105 .. 0.70

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 3.4e-06
   Cep57_CLD  97 vlekqaslekek...kqesselqaklekLekLEkeylrLtatqklaekkikeLeekLk 151
                 v ++ a l++++   k+++++ ++k + L++LE+e lrL+a+++   kki+eLe  + 
  EEA22422.1  33 VRNEAAYLKRREqvrKAQRTHRERKDQYLKTLESEVLRLRANEADFMKKIQELETHIF 90 
                 2223344444434545667777788889**************************9874 PP

>> ATG16  Autophagy protein 16 (ATG16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   7.1     8e-06     0.011      39     128 ..      25     113 ..       8     150 .. 0.68

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 8e-06
       ATG16  39 aklekaaasakssksskksakekeasasqsnskqsakiqsleqklaqlreelaelyksrgelaqrllelneelqkleeklkedeerlael 128
                 +   ++++s++++++  k +++ ++ ++++ +++++++++le+++++lr+  a+  k+ +el++ +  l+e++++ + +l + ee  +++
  EEA22422.1  25 KDK-SSSSSVRNEAAYLKRREQVRKAQRTHRERKDQYLKTLESEVLRLRANEADFMKKIQELETHIFHLQEAVKRSDVELPAIEEYSRSA 113
                 333.22233333222222222222222224567889999999999999999999999999999999999999999999888777665555 PP

>> TMCO5  TMCO5 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   2.3   1.5e-05     0.021      27     103 ..      24      98 ..      14     126 .. 0.72

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.5e-05
       TMCO5  27 qekeetiqslereitkldsllereedeeen.fsenekedalkeLeletaklekkneiLlkevveLqkkisrkeskqdd 103
                 ++ +++ +s ++e +    l++re+  + +    ++k++ lk Le e ++l  + +  +k++ eL+ +i ++++  ++
  EEA22422.1  24 DKDKSSSSSVRNEAAY---LKRREQVRKAQrTHRERKDQYLKTLESEVLRLRANEADFMKKIQELETHIFHLQEAVKR 98 
                 5555556666666665...444444444440455567778999********999999***********9988854333 PP

>> Fez1  Fez1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   4.2   1.6e-05     0.023      38     113 ..      31     106 ..      24     152 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1.6e-05
        Fez1  38 aqlrelrakleekeeeikeleesleektlelevcenelqrkkseaellrekvekleeelkelreelselsleeeea 113
                 +++r+  a l+++e+  k  ++++e k++ l+++e+e+ r ++++  + +k+++le+ + +l+e+++++  e    
  EEA22422.1  31 SSVRNEAAYLKRREQVRKAQRTHRERKDQYLKTLESEVLRLRANEADFMKKIQELETHIFHLQEAVKRSDVELPAI 106
                 678999999*****999999999999999***********99988889999************9988865543333 PP

>> Spore_GerAC  Spore germination B3/ GerAC like, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.2   3.6e-05     0.049      87     135 ..      56     103 ..      20     129 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 3.6e-05
                  -----HHHHHHHHHHHHHHHHHHHHHHHHTT----S-HHHHHHHH-HHH CS
  Spore_GerAC  87 leeeelkelekalekeiekeieealkklqeyksDilgfgeylrrkhpke 135
                   ++++lk+le+++ +  ++e ++++kk+qe+++ i+ + e ++r++ + 
   EEA22422.1  56 RKDQYLKTLESEVLRLRANE-ADFMKKIQELETHIFHLQEAVKRSDVEL 103
                  34555999999999999999.89*********************98764 PP

>> ANTH  ANTH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   2.6   4.2e-05     0.058      83     171 ..       9      93 ..       2     102 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 4.2e-05
                 ----TT---TSHHHSTHHHHHHHHHHHHHHHHHHHHHHHHHHSS-...CCCS--S.....TTSHCC.C--HHHHHHHHHHHHHHHHHHH CS
        ANTH  83 risellnlssfddssskswdysafiraYakyLderlefhrklkvdkgelereeegslvavedpnerktlsmeklldkieklqklldrll 171
                 + ++ll + +   s+ k++  s  +r+ a+yL++r + ++ ++ +    er+++   ++ e+++ r+  +  + ++ki++l+  ++ l 
  EEA22422.1   9 TRAHLLTGTHLLMSKDKDKSSSSSVRNEAAYLKRREQVRKAQRTH---RERKDQYL-KTLESEVLRLRANEADFMKKIQELETHIFHLQ 93 
                 55566666666666788999999**********************...77777774.44455555679999999999999999998775 PP

>> APG6_N  Apg6 coiled-coil region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   7.0   5.5e-05     0.076      18      96 ..      29     108 ..      17     120 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 5.5e-05
      APG6_N  18 leqaekerdaYeeflkklkkekkeeek.qdeeleeleeeleklekeeeelleeLkelekereeleaelaaleeelealee 96 
                  +++ +   aY++  ++++k +++ ++ +d+ l+ le e+ +l++ e++ +++++ele++   l+++++    el a+ee
  EEA22422.1  29 SSSSVRNEAAYLKRREQVRKAQRTHRErKDQYLKTLESEVLRLRANEADFMKKIQELETHIFHLQEAVKRSDVELPAIEE 108
                 455556666777777777766555444589999**********************************9999999988876 PP

>> FapA  Flagellar Assembly Protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.6   9.5e-05      0.13     343     419 ..      34     108 ..       7     139 .. 0.67

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 9.5e-05
        FapA 343 eeeleel..eeeleklkkkikklpklkaekqlesekkeqlkklletkeklkeeleeleeelkelkeeleskkeea.kikv 419
                 ++e   l  +e+++k +++    ++   ++q+ ++ ++++ +l+ +   ++++++ele++++ l+e ++++  e   i+ 
  EEA22422.1  34 RNEAAYLkrREQVRKAQRT---HRE--RKDQYLKTLESEVLRLRANEADFMKKIQELETHIFHLQEAVKRSDVELpAIEE 108
                 3333333223333333333...222..35688899999999999999*********************999444344444 PP

>> Prominin  Prominin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   1.5   0.00015      0.21     637     709 ..      24      97 ..       4     107 .. 0.75

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00015
    Prominin 637 anelsngk.knlkqslkneaqdlraiqqelvlplessvkklkksvkkldeensdlqesikkllaaveraenflk 709
                  ++ s+++    + ++ +  +++r+ q++  ++ ++ +k+l+++v +l +++ d+ ++i++l +++ ++++ +k
  EEA22422.1  24 DKDKSSSSsVRNEAAYLKRREQVRKAQRTHRERKDQYLKTLESEVLRLRANEADFMKKIQELETHIFHLQEAVK 97 
                 3333222213345667788899999999999999999***********************99999999888776 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   3.2   0.00019      0.27      53     123 ..      32     108 ..      17     116 .. 0.63
   2 ?    9.4   0.1    0.0008       1.1      27      85 ..      72     134 ..      70     150 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00019
                 HHHHHHHHHH..HHHHHHHHHHHHH.HHHHHHHHHH...HHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  53 eaeelvkeik..dslrekqkskkdn.dnvikksske...leeeilrlketidaqesnirvLqnvlesneqkiqkLeq 123
                 ++++   ++k  +++r++q+++++  d+++k +++e   l+ + +++ ++i++ e++i  Lq+ +++ ++++  +e+
  EEA22422.1  32 SVRNEAAYLKrrEQVRKAQRTHRERkDQYLKTLESEvlrLRANEADFMKKIQELETHIFHLQEAVKRSDVELPAIEE 108
                 33333333330034444444444434888888877633357778889999999999999999999988888877765 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.0008
                 CCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH....HHHHHHHHHH CS
   Fib_alpha  27 lkyekdvkkdlekleneleeisnstkeaeelvkeikdslrekqkskkdn....dnvikksske 85 
                    e d+ k++++le ++ ++++  k ++    +i+++ r++ +s+ +     ++ +++++++
  EEA22422.1  72 RANEADFMKKIQELETHIFHLQEAVKRSDVELPAIEEYSRSAPRSEVQLpvlaSSRTSNVAHD 134
                 556788999999999999999999999999999999999998888876522224444444444 PP

>> ABC_tran_Xtn  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   6.7   0.00046      0.63      17      70 ..      38      92 ..      35     108 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00046
  ABC_tran_Xtn 17 eyleekeerleqqqkayekqqkeikkleefIerfraka.kkakqaqsrekaLekl 70
                  +yl+ +e+ +++q+ ++e++ +++k le+ + r+ra++    k+ q+ e  + +l
    EEA22422.1 38 AYLKRREQVRKAQRTHRERKDQYLKTLESEVLRLRANEaDFMKKIQELETHIFHL 92
                  7**********************************96536666766666666555 PP

>> HisKA  His Kinase A (phospho-acceptor) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   1.5    0.0022         3      19      52 ..      32      72 ..      17      79 .. 0.83
   2 ?    1.8   0.0      0.18   2.5e+02       7      21 ..     129     143 ..     126     148 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0022
                HHHHHHHHHHC.........T-HSSCHHHHHHHHHHHHHHH CS
       HisKA 19 ailgnaeaLkre.......gklteelkeyletiesearrld 52
                +++  a  Lkr+          +e+  +yl+t+ese+ rl+
  EEA22422.1 32 SVRNEAAYLKRReqvrkaqRTHRERKDQYLKTLESEVLRLR 72
                5666677776666777777556799999**********998 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.18
                 HHHHHHHHHHHHHHH CS
       HisKA   7 agvaHELrtPLsail 21 
                 ++vaH+  tP sa++
  EEA22422.1 129 SNVAHDVSTPHSALQ 143
                 79*******977665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (156 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1810  (0.100954); expected 358.6 (0.02)
Passed bias filter:                      671  (0.0374254); expected 358.6 (0.02)
Passed Vit filter:                        81  (0.00451782); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 1018.20
//
Query:       EEA22423.1  [L=400]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (400 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       324  (0.0180713); expected 358.6 (0.02)
Passed bias filter:                      258  (0.0143901); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 2619.22
//
Query:       EEA22424.1  [L=372]
Description: hypothetical protein PMAA_090540 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-17   62.7   0.0    7.6e-17   61.4   0.0    1.6  1  DUF3425   Domain of unknown function (DUF3425)


Domain annotation for each model (and alignments):
>> DUF3425  Domain of unknown function (DUF3425)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.4   0.0   4.2e-21   7.6e-17      19     119 ..     234     325 ..     223     329 .. 0.85

  Alignments for each domain:
  == domain 1  score: 61.4 bits;  conditional E-value: 4.2e-21
     DUF3425  19 penlrPtelQlriaHpveidvlpwpelRdrllrafqeeeidedeffrdvvs............tlivWsieeeeletaeissaelsagdvtdlegWelk 105
                 p+ l+ t lQ+++ H+++id++p p++Rd++++ +q+  id d+++ d++             +li W                   gd+++  gWel+
  EEA22424.1 234 PPCLQFTFLQKTTSHEAWIDIVPSPTMRDNIIK-YQD-MIDADDLCSDFIGgavegandvhnrGLILW-------------------GDPWSSDGWELS 311
                 78889999*************************.555.4**********9855555555556666666...................9*********** PP

     DUF3425 106 esFfrkYpylvdgl 119
                 e+F++k++ l++++
  EEA22424.1 312 ENFVKKWWFLLEDC 325
                 ***********984 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (372 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       389  (0.0216967); expected 358.6 (0.02)
Passed bias filter:                      280  (0.0156172); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 2435.82
//
Query:       EEA22425.1  [L=372]
Description: hypothetical protein PMAA_090540 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-17   62.7   0.0    7.6e-17   61.4   0.0    1.6  1  DUF3425   Domain of unknown function (DUF3425)


Domain annotation for each model (and alignments):
>> DUF3425  Domain of unknown function (DUF3425)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.4   0.0   4.2e-21   7.6e-17      19     119 ..     234     325 ..     223     329 .. 0.85

  Alignments for each domain:
  == domain 1  score: 61.4 bits;  conditional E-value: 4.2e-21
     DUF3425  19 penlrPtelQlriaHpveidvlpwpelRdrllrafqeeeidedeffrdvvs............tlivWsieeeeletaeissaelsagdvtdlegWelk 105
                 p+ l+ t lQ+++ H+++id++p p++Rd++++ +q+  id d+++ d++             +li W                   gd+++  gWel+
  EEA22425.1 234 PPCLQFTFLQKTTSHEAWIDIVPSPTMRDNIIK-YQD-MIDADDLCSDFIGgavegandvhnrGLILW-------------------GDPWSSDGWELS 311
                 78889999*************************.555.4**********9855555555556666666...................9*********** PP

     DUF3425 106 esFfrkYpylvdgl 119
                 e+F++k++ l++++
  EEA22425.1 312 ENFVKKWWFLLEDC 325
                 ***********984 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (372 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       389  (0.0216967); expected 358.6 (0.02)
Passed bias filter:                      280  (0.0156172); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.24s 00:00:00.67 Elapsed: 00:00:00.38
# Mc/sec: 2932.55
//
Query:       EEA22426.1  [L=314]
Description: oxidoreductase, short-chain dehydrogenase/reductase family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.6e-23   82.0   0.0    4.3e-16   59.0   0.0    2.3  2  adh_short        short chain dehydrogenase
    1.5e-13   50.9   0.0      7e-11   42.1   0.0    2.1  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    3.2e-07   30.4   0.0    4.9e-07   29.8   0.0    1.2  1  KR               KR domain
    9.9e-06   25.2   0.0    1.6e-05   24.5   0.0    1.3  1  Epimerase        NAD dependent epimerase/dehydratase family
     0.0012   18.1   0.0     0.0027   16.9   0.0    1.5  2  Polysacc_synt_2  Polysaccharide biosynthesis protein
  ------ inclusion threshold ------
       0.13   12.1   0.0       0.19   11.6   0.0    1.2  1  PRMT5            PRMT5 arginine-N-methyltransferase


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.0   0.0   1.4e-19   4.3e-16       1     126 [.      22     146 ..      22     163 .. 0.89
   2 !   20.7   0.0   7.5e-08   0.00022     147     190 ..     189     232 ..     181     235 .. 0.91

  Alignments for each domain:
  == domain 1  score: 59.0 bits;  conditional E-value: 1.4e-19
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHT..TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGC CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvv.vdrseekleevakelkee..gakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfsel 96 
                 kv+++tG++sG+Gra +  lak++  ++  ++r++++++e++ e++ e  + k++++++D+t+  +v+++ ++ v  +++ld+L+ NAG+  +   + +
  EEA22426.1  22 KVIFITGGTSGLGRASVASLAKRNPAHIYfTGRNNKAAQELIHEVHTEkpSVKLTFVKMDMTSLVSVKEACKEFV--HDRLDILMCNAGV--MFIPAGV 116
                 89*******************988666665****************999999*******************9995..69***********..3444566 PP

                 SHHHHHHHHHHHTHHHHHHHHHHHHHHHHC CS
   adh_short  97 seeewervievNltgvflltravlpamlkq 126
                 s++ +e  +++N  +  +++++++p + k+
  EEA22426.1 117 SKDGFELHFAINHLAHAMIIQELMPVLQKS 146
                 7777*********************98754 PP

  == domain 2  score: 20.7 bits;  conditional E-value: 7.5e-08
                 HHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHH CS
   adh_short 147 aaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakel 190
                   Y+ sK a + ++ +la+++ +t+ir ++v+PG+v+T +++++
  EEA22426.1 189 FRYGQSKLANIVYAAELARQYPDTNIRFISVHPGAVNTHLTTSI 232
                 57*************************************99875 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.1   0.0   2.4e-14     7e-11       3     183 ..      30     233 ..      28     240 .. 0.80

  Alignments for each domain:
  == domain 1  score: 42.1 bits;  conditional E-value: 2.4e-14
                   TTSHHHH.HHHHHHHTT-EEEEEESSGGH.HHHHHHHHHHTTSE...EEE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHH CS
  adh_short_C2   3 asgIGra.iAkalaeeGaevvltdlneea.kkrveelaeelgae...vlecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsree 94 
                    sg+Gra +A +++++ a++ +t +n++a ++ ++e+++e ++    ++++D t+  +v+++ +e v+  ++lDil+ nag++       + +s+++
    EEA22426.1  30 TSGLGRAsVASLAKRNPAHIYFTGRNNKAaQELIHEVHTEKPSVkltFVKMDMTSLVSVKEACKEFVH--DRLDILMCNAGVMFI----PAGVSKDG 120
                   58999983566666778************99999**999988554534*****************996..59***********98....5789**** PP

                   HHHHHHHHTHHHHHHHHHHHHHCTSC.......CEEEEEEEGG...............G.TSB.STTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEE CS
  adh_short_C2  95 fdraldvnlyslfllakaalplmkeg.......gsivnlssvg...............a.erv.vpnynaygaaKaalealtrylAvelgpkgiRvN 167
                   f+  +++n  + ++++++++p+++++        ++++l+s++                 +r+ + +y  yg +K a +  +  lA+++ + +iR  
    EEA22426.1 121 FELHFAINHLAHAMIIQELMPVLQKSasqpssdVRVLCLTSTAwmshpsdgitfstlrTpQRGfMGSYFRYGQSKLANIVYAAELARQYPDTNIRFI 217
                   *********************9988867777664466666654222222222221111223333566669*************************** PP

                   EEEE--BHCTGGGGST CS
  adh_short_C2 168 avspgpikTlaasgik 183
                   +v+pg+++T ++++i+
    EEA22426.1 218 SVHPGAVNTHLTTSIP 233
                   ***********99886 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.8   0.0   1.7e-10   4.9e-07       3      79 ..      24      99 ..      22     120 .. 0.87

  Alignments for each domain:
  == domain 1  score: 29.8 bits;  conditional E-value: 1.7e-10
                EEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHT..T-EEEE----TT-HHHHHHHHHHHHHHS CS
          KR  3 ylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaeleal..gaevevvaaDvsdkdavealleeikaee 79
                 +itGG+ gLG++ +  la++  +h+ +++R+   ++++++li+e++     ++ ++v++D ++  +v+++ +e+ ++ 
  EEA22426.1 24 IFITGGTSGLGRASVASLAKRNPAHIYFTGRN---NKAAQELIHEVHTEkpSVKLTFVKMDMTSLVSVKEACKEFVHDR 99
                57******************************...6777889999887645889999*************999987654 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.5   0.0   5.5e-09   1.6e-05       1     164 [.      24     214 ..      24     225 .. 0.75

  Alignments for each domain:
  == domain 1  score: 24.5 bits;  conditional E-value: 5.5e-09
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC.........EEEE--TT-HHHHHHHHHHH...T-SEEEE--S---HHHHHHSHH.. CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl.........elveldltdrsalerlfkee...qpdavihlAavggvaassedpa.. 85 
                 i++tG+t  +G+a v  l++++   i ++ ++++ ++++++++         ++v++d+t  +++++++ke+   + d+ +  A+v  ++a +++    
  EEA22426.1  24 IFITGGTSGLGRASVASLAKRNPAHIYFTGRNNKAAQELIHEVhtekpsvklTFVKMDMTSLVSVKEACKEFvhdRLDILMCNAGVMFIPAGVSKDGfe 122
                 79********************88777777778888888888889******************999988886545888888889999999988876411 PP

                 HHHHHHTHHHHHHHHHHH..........HHTCTEEEEEEEGGGGTSCSS.SS.BSTCSTTS--.--SSHHHHHHHHHHHHHHHHHHHH.T-EE CS
   Epimerase  86 dfieknlqgtlnlleaar..........kagvkrllflsSsevYGkdae.qp.keettltgpl.kpnspYaaaKlageklveayaaqy.glna 164
                   + +n      +++++            ++v r+l l S+++   + + +   +  t +  +  +   Y+ +Kla   ++ ++a+qy ++n+
  EEA22426.1 123 LHFAINHLAHAMIIQELMpvlqksasqpSSDV-RVLCLTSTAWMSHPSDgITfSTLRTPQRGFmGSYFRYGQSKLANIVYAAELARQYpDTNI 214
                 23335555444444444457777766555566.9999999999998888542345555444558999*********************75443 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.0   8.9e-07    0.0027       1      82 [.      24     104 ..      24     118 .. 0.80
   2 ?   -2.7   0.0      0.83   2.5e+03     138     171 ..     191     224 ..     190     226 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 8.9e-07
                      EEEETTTSHHHHHHHHHHHHHB-SEEEEEES-HHHHHHHHHH......-TTEEEE....E--TT-HHHHHHHTT..T-SEEE CS
  Polysacc_synt_2   1 vlvtGagGsiGselvrqilkkkpkkiillerdElklyeiekeleeelkkkklkveivpvigdvrdkerlekaleelkvdvvf 82 
                      +++tG++  +G++ v  ++k++p++i+   r+ ++ +e+ +e+++e+ + kl++  + +   v  ke +++ ++  + d+++
       EEA22426.1  24 IFITGGTSGLGRASVASLAKRNPAHIYFTGRNNKAAQELIHEVHTEKPSVKLTFVKMDMTSLVSVKEACKEFVH-DRLDILM 104
                      78****************************************98888888887776666666666666666665.4555555 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 0.83
                      HHHHHHHHHHHHHHGGG--SSS--EEEEEEE-EE CS
  Polysacc_synt_2 138 mGatKrlaekllqalakeseekktkfvvvRfGNV 171
                      +G +K++   ++ +la++  +++ +f+ v  G V
       EEA22426.1 191 YGQSKLANIVYAAELARQYPDTNIRFISVHPGAV 224
                      7889998888888999998888899998877765 PP

>> PRMT5  PRMT5 arginine-N-methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   6.2e-05      0.19      66     136 ..      22      89 ..       4     107 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 6.2e-05
                 EEEEEES-TTSHHHHHHHHHHHHHCCCEEEEEEEES-HHHHHHHHHHHHHHTTCCGCEEEES-CCCCCHCC CS
       PRMT5  66 lvilvvGaGRGplvdralkaleetkvtkvkivavEKnpnavvtLqkkvneekWeekveviksdmrelkaee 136
                  vi++ G G  +l ++++ +l++ +    +i+   +n++a   L ++v++ek + k++ +k dm +l + +
  EEA22426.1  22 KVIFITG-GTSGLGRASVASLAKRN--PAHIYFTGRNNKAAQELIHEVHTEKPSVKLTFVKMDMTSLVSVK 89 
                 4555555.67779999999998888..99***********************************9986654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (314 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       548  (0.030565); expected 358.6 (0.02)
Passed bias filter:                      514  (0.0286686); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.41
# Mc/sec: 2325.53
//
Query:       EEA22427.1  [L=375]
Description: class V chitinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.1e-71  239.3   0.4    9.2e-71  239.1   0.4    1.0  1  Glyco_hydro_18  Glycosyl hydrolases family 18


Domain annotation for each model (and alignments):
>> Glyco_hydro_18  Glycosyl hydrolases family 18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  239.1   0.4   5.1e-75   9.2e-71       3     312 .]      20     357 ..      18     357 .. 0.89

  Alignments for each domain:
  == domain 1  score: 239.1 bits;  conditional E-value: 5.1e-75
                     EEEEEGGGGGSSGCSH....TTTESEEEEEEEEEEE.TTTEEEESSTTHHHHHHHHHHHHHHTSTT-EEEEEEEETTTTTHHHHHHTSHHHHHHH CS
                     xxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18   3 vgYysswesygnnylp....saklthiiyaFakidg.engkvvvsdwedlgnfeqlkklkkkknpgvkvllsiGGwtdssgfslaastdasrkkf 92 
                     v+Y+++w+ ++   lp     + +th i+aFa  d+ ++g       + +++fe +++ ++++   +k+l++iGGw++++gfs a+ +++sr ++
      EEA22427.1  20 VMYVDQWHHSN---LPssdlVSSVTHAIMAFAPSDNfNSG-------STFTPFESIATFRARFPSTTKILVAIGGWGYNAGFSAAVLSETSRSTY 104
                     9*******996...5556679***********88773232.......23489********99999****************************** PP

                     HHHHHHHHHHCT-SEEEEEES-TTTS............TCHHHHHHHHHHHHHHHHHHHHHHTSTTCEEEEEEESSHHHHHHH..CHHHHHHHHT CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxx............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxx RF
  Glyco_hydro_18  93 adsvvsllrkygfDGiDidweypggn............pedkenytallkelrealdkakategkkllLsaavpasasdlskg..ydlpkiakyl 173
                     a++v+++l+  g+DG+Didweypggn            +++ +++++l++++r a++       ++++Ls+a+p+ ++d++ +  +  p++ +++
      EEA22427.1 105 AQNVAAMLESTGLDGVDIDWEYPGGNgadyksipnsqrADEVTTFPLLIRAIRDAIG-------NDKILSLAAPGLRRDMMGFtsDTGPAVFDVV 192
                     *********************************99999888*************665.......889************666688999******* PP

                     SEEEEETTTSSSTTSSBE--SS-SSBTCSSHHHHHHHHHHTT--GGGEEEEEESEEEEEEESSSSSS...........................T CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...........................x RF
  Glyco_hydro_18 174 DyvnvmtYDfhgswdnvtghhaplydaslnvdeavkeylkagvpakklvlGvpfygrawalvsgadn...........................t 241
                     D+vn+mtYD+++++dnvt+hh+ +      + e+v++yl  g++a k +lG++fy++ ++++  +d                             
      EEA22427.1 193 DMVNIMTYDLMNRRDNVTKHHTCI----KDSLETVNNYLGIGMNATKGNLGIAFYAKYFTTDPSSDCattpigcatvlledangqdtgksgavtF 283
                     ************************....*********************************9997778888888888888888899666666632 PP

                     STTTEEEHHHHHHHHTEEEEEEEEETTTTEEEEEETT..EEEEE-SHHHHHHHH.HHHHHTTESEEEEETGGGS CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_18 242 keegvlsykelkellkkakakrkydskakapyvydge..efvsyDdpksikaka.dyvkakglgGvmiWsldqD 312
                     + ++ +s + + ++  kak+++ +d++a+++y++d +   f+++D+p+ i++k+ +++ a glgGvm+Wsl++D
      EEA22427.1 284 ETNPEVSSSSITSSWSKAKSNGLTDEDAGGQYYWDRDsqLFWTWDTPELITRKFtEIIAATGLGGVMAWSLGED 357
                     22333444445555599*******************************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (375 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       376  (0.0209716); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2613.97
//
Query:       EEA22428.1  [L=388]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.6e-08   33.8  11.3      5e-08   32.9  11.3    1.4  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
    1.6e-06   27.2   3.2    1.6e-06   27.2   3.2    1.5  2  Fungal_trans_2  Fungal specific transcription factor domain
  ------ inclusion threshold ------
       0.92    9.3   5.4          2    8.3   5.4    1.5  1  DUF2797         Protein of unknown function (DUF2797)


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.9  11.3   8.4e-12     5e-08       1      36 [.      36      70 ..      36      74 .. 0.92

  Alignments for each domain:
  == domain 1  score: 32.9 bits;  conditional E-value: 8.4e-12
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfyses 36
                h+C +C+++KvKCd ++P Cs+C+++   C+ y e 
  EEA22428.1 36 HGCLTCKSRKVKCDFQRPICSHCQRRKERCE-YAEA 70
                89*****************************.7664 PP

>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.2   3.2   2.7e-10   1.6e-06       2     110 ..     107     219 ..     106     263 .. 0.74
   2 ?   -2.9   0.0      0.36   2.2e+03      62      87 ..     294     330 ..     279     364 .. 0.61

  Alignments for each domain:
  == domain 1  score: 27.2 bits;  conditional E-value: 2.7e-10
  Fungal_trans_2   2 lldyyldnvapllspvpessnpfrkvllplalsnkallhallalsafhl.qskgpkds.....lereakrykslalkelqealaelsstlsrnek 90 
                     ll+++ + v+ +ls   +    +   + + a + ++l+h++la sa+hl q++ pk+s     +   a++++++al++l    + +++       
      EEA22428.1 107 LLHHFSSTVSLTLSDREDFHTVWSIHVPQDAYKYPHLMHSMLATSALHLsQTTTPKESadisfYAALATHHHVMALSLLTPHVTSVTMENF---- 197
                     79*******9988888888******************************655666664666666677777777777777777666666666.... PP

  Fungal_trans_2  91 ykdiLaaiLllcsie...issgd 110
                      +++ a+ +l  ++    ++s+d
      EEA22428.1 198 -DSLYATSMLIFLFNvglMASSD 219
                     .7777777887777666433333 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 0.36
  Fungal_trans_2  62 eakrykslalkelqealaelsstls...........r 87 
                     eak  +++a+k+l+   + ++ + +            
      EEA22428.1 294 EAKTEYQEAIKLLRATFNAVNLNRQhpamvfmwftlV 330
                     4555566677777777776666666555555555553 PP

>> DUF2797  Protein of unknown function (DUF2797)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   5.4   0.00033         2      12      59 ..      36      84 ..      29      94 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00033
     DUF2797 12 rrCvnC.grktkksfsqgvCakCfkklaeadecimkpekchahlgtclr 59
                  C+ C  rk+k  f+   C +C ++  +++   + pe++h  l    +
  EEA22428.1 36 HGCLTCkSRKVKCDFQRPICSHCQRRKERCEYAEAAPEQSHNRLHRRNA 84
                56****77999999***************************98876654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (388 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       822  (0.0458475); expected 358.6 (0.02)
Passed bias filter:                      485  (0.0270511); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.40
# Mc/sec: 2893.65
//
Query:       EEA22429.1  [L=644]
Description: hypothetical protein PMAA_090580 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (644 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       359  (0.0200234); expected 358.6 (0.02)
Passed bias filter:                      150  (0.00836633); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.40
# Mc/sec: 4844.66
//
Query:       EEA22430.1  [L=248]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-16   60.9   0.5    2.4e-16   60.2   0.5    1.4  1  CVNH      CVNH domain


Domain annotation for each model (and alignments):
>> CVNH  CVNH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.2   0.5   1.4e-20   2.4e-16       1     100 [.      31     128 ..      31     129 .. 0.92

  Alignments for each domain:
  == domain 1  score: 60.2 bits;  conditional E-value: 1.4e-20
                 GGGSEEEEEEETT...EEEEEEE-TTSSEEEEEEEGGGTEEEETTEEEE...-BGGGSEEEEEEE--E....EEEEEEET.SS-EE.EEEEEGGGTEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxx RF
        CVNH   1 FskscrdirldahgetiLhAecrredgsyqsssidLnkcigndnGslrw...gnfsesarnvrleeggeeeqvLeaeler.dgewvesseinLderIsN 95 
                 Fs+ c++i++   +++ L+A+c ++ g+  ss + L ++++n++G+l+w   g + +s++++ l + g    +L++ ++    + + +s++nL+e+I+N
  EEA22430.1  31 FSSKCSNITF---NTNWLVANCPNDAGTLVSSGVYLPSYVTNTEGKLEWkadGAYEQSCSDCVLLDSG---ATLQCYCRGtFTKENGNSTLNLEEYIAN 123
                 99********...567************9999*******************99***********9655...9*****9866677777888********* PP

                 ETTEE CS
                 xxxxx RF
        CVNH  96 nnGtL 100
                  nG+L
  EEA22430.1 124 YNGHL 128
                 ***98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (248 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       433  (0.0241508); expected 358.6 (0.02)
Passed bias filter:                      317  (0.0176809); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1673.91
//
Query:       EEA22431.1  [L=582]
Description: TPR domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    3.1e-10   39.4   9.9      0.017   15.2   0.0    6.8  6  TPR_2       Tetratricopeptide repeat
    1.5e-09   37.3   6.3       0.13   12.2   0.0    6.6  6  TPR_1       Tetratricopeptide repeat
    3.4e-08   33.9   5.1     0.0014   19.1   0.0    5.4  5  TPR_19      Tetratricopeptide repeat
    1.2e-07   31.9   5.4       0.03   14.6   0.7    5.7  6  TPR_12      Tetratricopeptide repeat
    9.1e-07   28.5  12.9      0.005   16.5   0.0    5.3  6  TPR_11      TPR repeat
    5.5e-06   26.0   0.7        3.1    8.0   0.0    4.6  3  TPR_7       Tetratricopeptide repeat
    5.8e-06   26.1   4.8        7.5    7.0   0.1    6.6  6  TPR_8       Tetratricopeptide repeat
    7.2e-05   23.4   9.2       0.14   12.9   0.0    6.3  7  TPR_16      Tetratricopeptide repeat
    0.00017   21.9   2.0       0.38   11.5   0.1    4.2  3  TPR_4       Tetratricopeptide repeat
     0.0084   16.8   9.5        2.8    9.0   0.1    6.0  5  TPR_14      Tetratricopeptide repeat
     0.0087   16.3   0.7       0.33   11.2   0.1    3.9  4  ANAPC3      Anaphase-promoting complex, cyclosome, subunit 3
  ------ inclusion threshold ------
       0.01   16.1   6.8        2.6    8.6   0.0    5.1  6  TPR_17      Tetratricopeptide repeat
      0.011   15.3   0.0      0.088   12.4   0.0    2.5  3  HrpB1_HrpK  Bacterial type III secretion protein (HrpB1_HrpK)
      0.082   13.0   0.2         72    3.6   0.0    4.2  4  MIT         MIT (microtubule interacting and transport) domai
        4.2    7.5   9.8        1.4    8.9   0.2    4.3  5  TPR_3       Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   1.4e-05     0.017       1      33 [.      38      70 ..      38      71 .. 0.94
   2 ?    1.3   0.1      0.41     5e+02      15      32 ..     274     291 ..     272     293 .. 0.81
   3 !    6.4   0.3    0.0092        11       3      21 ..     393     411 ..     392     423 .. 0.90
   4 ?    5.6   0.1     0.016        19       8      32 ..     448     472 ..     445     474 .. 0.91
   5 !    9.9   0.1   0.00072      0.86       6      25 ..     489     508 ..     487     514 .. 0.89
   6 ?   -0.0   0.0       1.1   1.3e+03      12      21 ..     538     547 ..     535     549 .. 0.80

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1.4e-05
       TPR_2  1 aealynlGlayyklgdyeeAleafekAleldPn 33
                a+ ++ +Gl++  + ++eeA+++f+ A++ dP+
  EEA22431.1 38 AQTWFDRGLIWTFAFNHEEAVNCFKNAIRDDPE 70
                678**************************9997 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.41
       TPR_2  15 gdyeeAleafekAleldP 32 
                 gdy++A++   +A++ d+
  EEA22431.1 274 GDYQQAIRSNTQAIQADE 291
                 99****998888888776 PP

  == domain 3  score: 6.4 bits;  conditional E-value: 0.0092
       TPR_2   3 alynlGlayyklgdyeeAl 21 
                 ++y+ G a ++lg+ eeA+
  EEA22431.1 393 LHYAKGVASAALGRIEEAE 411
                 69****************7 PP

  == domain 4  score: 5.6 bits;  conditional E-value: 0.016
       TPR_2   8 GlayyklgdyeeAleafekAleldP 32 
                 G++ y++ + e+A  ++++A +ld 
  EEA22431.1 448 GEIEYRKSNIEQAFIYLRQATKLDQ 472
                 788999*****************96 PP

  == domain 5  score: 9.9 bits;  conditional E-value: 0.00072
       TPR_2   6 nlGlayyklgdyeeAleafe 25 
                 + G +++++g++eeAl+ + 
  EEA22431.1 489 AYGALLLEQGQFEEALDVYS 508
                 6799************9996 PP

  == domain 6  score: -0.0 bits;  conditional E-value: 1.1
       TPR_2  12 yklgdyeeAl 21 
                   l++y+eA+
  EEA22431.1 538 TTLKRYDEAR 547
                 5689*****8 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.2   0.0   0.00011      0.13       1      29 [.      38      66 ..      38      71 .. 0.93
   2 !    6.9   0.1    0.0049       5.9      15      34 .]     274     293 ..     272     293 .. 0.90
   3 ?    3.3   0.1     0.067        80       4      21 ..     394     411 ..     392     412 .. 0.92
   4 ?    1.8   0.1       0.2   2.3e+02       9      32 ..     449     472 ..     448     474 .. 0.86
   5 !    8.8   0.0    0.0012       1.5       8      25 ..     491     508 ..     491     509 .. 0.91
   6 ?    0.4   0.0      0.57   6.8e+02      10      20 ..     536     546 ..     535     547 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00011
                HHHHHHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1  1 akalynlGnayfklgkydeAleyyekALe 29
                a++++ +G++     +++eA+ +++ A++
  EEA22431.1 38 AQTWFDRGLIWTFAFNHEEAVNCFKNAIR 66
                789************************96 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0049
                 T-HHHHHHHHHHHHHHSTTH CS
       TPR_1  15 gkydeAleyyekALelnPnn 34 
                 g+y++A+    +A++ ++++
  EEA22431.1 274 GDYQQAIRSNTQAIQADEKY 293
                 9**************99875 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.067
                 HHHHHHHHHHTT-HHHHH CS
       TPR_1   4 lynlGnayfklgkydeAl 21 
                 +y +G+a   lg+ +eA+
  EEA22431.1 394 HYAKGVASAALGRIEEAE 411
                 899**************7 PP

  == domain 4  score: 1.8 bits;  conditional E-value: 0.2
                 HHHHHTT-HHHHHHHHHHHHHHST CS
       TPR_1   9 nayfklgkydeAleyyekALelnP 32 
                  + +++ + ++A  y ++A +l+ 
  EEA22431.1 449 EIEYRKSNIEQAFIYLRQATKLDQ 472
                 56688999**************97 PP

  == domain 5  score: 8.8 bits;  conditional E-value: 0.0012
                 HHHHHHTT-HHHHHHHHH CS
       TPR_1   8 GnayfklgkydeAleyye 25 
                 G++++++g+++eAl+ y+
  EEA22431.1 491 GALLLEQGQFEEALDVYS 508
                 8899**********9885 PP

  == domain 6  score: 0.4 bits;  conditional E-value: 0.57
                 HHHHTT-HHHH CS
       TPR_1  10 ayfklgkydeA 20 
                 ++  l++ydeA
  EEA22431.1 536 CLTTLKRYDEA 546
                 78899*****9 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.0      0.15   1.7e+02       6      33 ..      53      80 ..      51      82 .. 0.84
   2 !    7.0   0.3    0.0067       8.1      17      38 ..     166     187 ..     153     188 .. 0.85
   3 ?    1.4   0.0      0.39   4.7e+02       5      24 ..     274     293 ..     273     308 .. 0.88
   4 ?   -0.9   0.1         2   2.4e+03      36      46 ..     402     412 ..     393     413 .. 0.79
   5 !   19.1   0.0   1.1e-06    0.0014       1      45 [.     494     547 ..     494     558 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.15
      TPR_19  6 dyaeAlalleqalqedpknaearllLAe 33
                +++eA++ +++a+ +dp+   a  +LA 
  EEA22431.1 53 NHEEAVNCFKNAIRDDPECTIAYWGLAY 80
                6899*************98888777775 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.0067
      TPR_19  17 alqedpknaearllLAeallal 38 
                 a++ +p+++++++l+A+al++l
  EEA22431.1 166 AYKNNPDDLDIAALYADALMNL 187
                 6788***************975 PP

  == domain 3  score: 1.4 bits;  conditional E-value: 0.39
      TPR_19   5 gdyaeAlalleqalqedpkn 24 
                 gdy++A++  +qa+q+d k+
  EEA22431.1 274 GDYQQAIRSNTQAIQADEKY 293
                 8*******999999999886 PP

  == domain 4  score: -0.9 bits;  conditional E-value: 2
      TPR_19  36 lalgqldeAea 46 
                  alg+++eAe+
  EEA22431.1 402 AALGRIEEAEN 412
                 689******96 PP

  == domain 5  score: 19.1 bits;  conditional E-value: 1.1e-06
      TPR_19   1 llaegdyaeAlalleq..........alqedpknaearllLAeallalgqldeAe 45 
                 ll++g+++eAl+ ++           a  + p+n + + +L+e+l  l+++deA+
  EEA22431.1 494 LLEQGQFEEALDVYSTdlglndilprA-MQHPNNVWSLHGLVECLTTLKRYDEAR 547
                 79*************976655544433.448***********************8 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0      0.97   1.2e+03      59      71 ..      52      64 ..      32      68 .. 0.58
   2 ?    2.6   0.0      0.14   1.7e+02      17      35 ..     274     292 ..     270     304 .. 0.66
   3 ?   -0.4   0.0       1.2   1.4e+03       8      23 ..     396     411 ..     389     428 .. 0.71
   4 ?    5.6   0.4     0.016        19      13      76 ..     411     472 ..     399     473 .. 0.72
   5 !   14.6   0.7   2.5e-05      0.03       2      68 ..     441     507 ..     440     509 .. 0.94
   6 !    9.6   0.0   0.00089       1.1      40      67 ..     522     549 ..     518     555 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.97
      TPR_12 59 gryeeAlelleea 71
                 ++eeA++ ++ a
  EEA22431.1 52 FNHEEAVNCFKNA 64
                4566666665544 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.14
      TPR_12  17 grydeAlellekaleiarr 35 
                 g+y++A++   +a+++ ++
  EEA22431.1 274 GDYQQAIRSNTQAIQADEK 292
                 5555555555555555555 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 1.2
      TPR_12   8 nlaavlrrlgrydeAl 23 
                   +++ ++lgr +eA+
  EEA22431.1 396 AKGVASAALGRIEEAE 411
                 4666667777777776 PP

  == domain 4  score: 5.6 bits;  conditional E-value: 0.016
      TPR_12  13 lrrlgrydeAlellekaleiarrllGpdh.pltattlrnLgrlyralgryeeAlelleealaiae 76 
                 +++++ + +Al + + ++ i++++  + h +++a ++ n g++ ++  + e+A  +l++a+++++
  EEA22431.1 411 ENERELFKKALMHVQPSRTIFNNS--CLHiLQVADAMLN-GEIEYRKSNIEQAFIYLRQATKLDQ 472
                 566777888888888888888888..8884444555555.6665566699999999999998876 PP

  == domain 5  score: 14.6 bits;  conditional E-value: 2.5e-05
      TPR_12   2 vatalnnlaavlrrlgrydeAlellekaleiarrl.lGpdhpltattlrnLgrlyralgryeeAlell 68 
                 va a+   +++++r  + ++A+ +l++a  + ++l +++ + +    ++++g l++++g++eeAl+ +
  EEA22431.1 441 VADAM-LNGEIEYRKSNIEQAFIYLRQATKLDQELpYDEPWGWMQPPRHAYGALLLEQGQFEEALDVY 507
                 66677.799********************************************************987 PP

  == domain 6  score: 9.6 bits;  conditional E-value: 0.00089
      TPR_12  40 dhpltattlrnLgrlyralgryeeAlel 67 
                 +hp+ +++l++L +++  l+ry+eA+ l
  EEA22431.1 522 QHPNNVWSLHGLVECLTTLKRYDEARLL 549
                 5999999999999999999999999865 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.1       5.7   6.8e+03       2      10 ..      19      27 ..      19      28 .. 0.83
   2 !   16.5   0.0   4.2e-06     0.005      10      37 ..      54      81 ..      53      83 .. 0.94
   3 ?    3.8   0.1     0.038        46       7      27 ..     273     293 ..     268     296 .. 0.86
   4 ?   -3.0   0.0         5     6e+03       6      13 ..     403     410 ..     394     410 .. 0.68
   5 ?    4.3   0.2     0.027        32       1      28 [.     448     475 ..     448     476 .. 0.92
   6 !    9.3   0.0   0.00073      0.88       3      18 ..     493     508 ..     491     509 .. 0.87

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 5.7
      TPR_11  2 dayyeqGky 10
                d y+++G y
  EEA22431.1 19 DKYFDLGSY 27
                679999998 PP

  == domain 2  score: 16.5 bits;  conditional E-value: 4.2e-06
      TPR_11 10 yeeAieaYkkAlkldPdnaeayynLGla 37
                 eeA++++k+A++ dP+   ay++L++a
  EEA22431.1 54 HEEAVNCFKNAIRDDPECTIAYWGLAYA 81
                79***********************987 PP

  == domain 3  score: 3.8 bits;  conditional E-value: 0.038
      TPR_11   7 qGkyeeAieaYkkAlkldPdn 27 
                  G+y +Ai +  +A++ d+++
  EEA22431.1 273 CGDYQQAIRSNTQAIQADEKY 293
                 79********99**9999887 PP

  == domain 4  score: -3.0 bits;  conditional E-value: 5
      TPR_11   6 eqGkyeeA 13 
                 ++G++eeA
  EEA22431.1 403 ALGRIEEA 410
                 57777777 PP

  == domain 5  score: 4.3 bits;  conditional E-value: 0.027
      TPR_11   1 GdayyeqGkyeeAieaYkkAlkldPdna 28 
                 G + y + ++e+A   +++A kld++ +
  EEA22431.1 448 GEIEYRKSNIEQAFIYLRQATKLDQELP 475
                 789999******************9987 PP

  == domain 6  score: 9.3 bits;  conditional E-value: 0.00073
      TPR_11   3 ayyeqGkyeeAieaYk 18 
                 ++ eqG++eeA+ +Y+
  EEA22431.1 493 LLLEQGQFEEALDVYS 508
                 688************7 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.6   0.0    0.0035       4.2       6      33 ..      45      70 ..      40      71 .. 0.84
   2 !    8.0   0.0    0.0026       3.1      12      28 ..     273     287 ..     267     292 .. 0.79
   3 ?    5.0   0.0     0.024        29       7      26 ..     492     511 ..     488     519 .. 0.82

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0035
       TPR_7  6 arlysrlGdyeeAielyeqsLaltkdpe 33
                + ++    ++eeA+ +++   a+++dpe
  EEA22431.1 45 GLIWTFAFNHEEAVNCFKN--AIRDDPE 70
                566777789**********..*****97 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0026
       TPR_7  12 lGdyeeAielyeqsLal 28 
                 +Gdy++Ai+ ++q  a+
  EEA22431.1 273 CGDYQQAIRSNTQ--AI 287
                 8************..54 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.024
       TPR_7   7 rlysrlGdyeeAielyeqsL 26 
                  l  ++G++eeA+++y   L
  EEA22431.1 492 ALLLEQGQFEEALDVYSTDL 511
                 67889**********97655 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.4   0.0    0.0099        12       1      32 [.      38      69 ..      38      71 .. 0.84
   2 ?    1.5   0.1      0.36   4.3e+02      15      33 ..     274     292 ..     272     293 .. 0.90
   3 ?    2.6   0.1      0.16   1.9e+02       4      21 ..     394     411 ..     393     421 .. 0.87
   4 !    7.0   0.1    0.0063       7.5      13      32 ..     453     472 ..     448     474 .. 0.84
   5 ?    2.5   0.0      0.18   2.1e+02       7      24 ..     490     507 ..     487     509 .. 0.85
   6 ?    0.2   0.0      0.99   1.2e+03       7      21 ..     533     547 ..     529     548 .. 0.79

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0099
                CCHHHHHHHHHHHTT-HHHHHHHHHHHHHHHH CS
       TPR_8  1 aeayynlgsiylklgdyeeAkeyyekaleldp 32
                a+ ++  g+i     ++eeA+ +++ a++ dp
  EEA22431.1 38 AQTWFDRGLIWTFAFNHEEAVNCFKNAIRDDP 69
                578888888888999************98666 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.36
                 T-HHHHHHHHHHHHHHHHH CS
       TPR_8  15 gdyeeAkeyyekaleldpd 33 
                 gdy++A+ +  +a+++d++
  EEA22431.1 274 GDYQQAIRSNTQAIQADEK 292
                 9********9999999987 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.16
                 HHHHHHHHHHTT-HHHHH CS
       TPR_8   4 yynlgsiylklgdyeeAk 21 
                 +y +g +   lg++eeA+
  EEA22431.1 394 HYAKGVASAALGRIEEAE 411
                 689999999*******97 PP

  == domain 4  score: 7.0 bits;  conditional E-value: 0.0063
                 HTT-HHHHHHHHHHHHHHHH CS
       TPR_8  13 klgdyeeAkeyyekaleldp 32 
                  + ++e+A  y+++a++ld+
  EEA22431.1 453 RKSNIEQAFIYLRQATKLDQ 472
                 56799*************97 PP

  == domain 5  score: 2.5 bits;  conditional E-value: 0.18
                 HHHHHHHTT-HHHHHHHH CS
       TPR_8   7 lgsiylklgdyeeAkeyy 24 
                  g ++l++g++eeA  +y
  EEA22431.1 490 YGALLLEQGQFEEALDVY 507
                 688999********8877 PP

  == domain 6  score: 0.2 bits;  conditional E-value: 0.99
                 HHHHHHHTT-HHHHH CS
       TPR_8   7 lgsiylklgdyeeAk 21 
                 l  ++ +l++y+eA 
  EEA22431.1 533 LVECLTTLKRYDEAR 547
                 5667889******95 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.9   0.0   0.00011      0.14      13      43 ..      54      81 ..      53      82 .. 0.94
   2 ?   -2.3   0.1       6.1   7.3e+03      24      44 ..     167     184 ..     166     187 .. 0.69
   3 ?   -1.7   0.0       4.2     5e+03      11      25 ..     274     288 ..     274     292 .. 0.70
   4 ?    3.5   0.0     0.093   1.1e+02      36      54 ..     393     411 ..     390     419 .. 0.90
   5 ?   -1.7   0.0       4.1   4.8e+03      41      62 ..     448     469 ..     444     475 .. 0.72
   6 ?    5.0   0.0     0.034        40       5      21 ..     492     508 ..     489     521 .. 0.80
   7 ?    1.1   0.0      0.54   6.4e+02      39      57 ..     532     549 ..     523     558 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 0.00011
      TPR_16 13 yddAaaaleaalkrdpssPdaaeAllllgda 43
                 ++A++ ++ a+++d   P++  A+++l+ a
  EEA22431.1 54 HEEAVNCFKNAIRDD---PECTIAYWGLAYA 81
                699************...**********987 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 6.1
      TPR_16  24 lkrdpssPdaaeAllllgdaa 44 
                  k++   Pd+ + + l++da+
  EEA22431.1 167 YKNN---PDDLDIAALYADAL 184
                 5677...78777777777776 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 4.2
      TPR_16  11 gdyddAaaaleaalk 25 
                 gdy++A++  ++a+ 
  EEA22431.1 274 GDYQQAIRSNTQAIQ 288
                 788888887666655 PP

  == domain 4  score: 3.5 bits;  conditional E-value: 0.093
      TPR_16  36 AllllgdaalrqgrlaeAa 54 
                  ++++g+a +++gr +eA+
  EEA22431.1 393 LHYAKGVASAALGRIEEAE 411
                 69****************8 PP

  == domain 5  score: -1.7 bits;  conditional E-value: 4.1
      TPR_16  41 gdaalrqgrlaeAaalyraalr 62 
                 g++ +r+++ + A  ++r a +
  EEA22431.1 448 GEIEYRKSNIEQAFIYLRQATK 469
                 7788888888888888887754 PP

  == domain 6  score: 5.0 bits;  conditional E-value: 0.034
      TPR_16   5 raalragdyddAaaale 21 
                  ++l++g++++A+ ++ 
  EEA22431.1 492 ALLLEQGQFEEALDVYS 508
                 46788888888888875 PP

  == domain 7  score: 1.1 bits;  conditional E-value: 0.54
      TPR_16  39 llgdaalrqgrlaeAaaly 57 
                 +l +++  ++r++eA+ l+
  EEA22431.1 532 GLVECLTTLKRYDEAR-LL 549
                 57789999*******8.55 PP

>> TPR_4  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.1   0.1    0.0086        10       3      21 ..     393     411 ..     391     415 .. 0.90
   2 !   11.5   0.1   0.00032      0.38       3      23 ..     486     506 ..     484     507 .. 0.90
   3 ?   -2.3   0.0       9.3   1.1e+04       2      21 ..     528     547 ..     527     547 .. 0.70

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0086
       TPR_4   3 allaLArallalGdldeAr 21 
                 +++a + a +alG+ +eA+
  EEA22431.1 393 LHYAKGVASAALGRIEEAE 411
                 689999************8 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 0.00032
       TPR_4   3 allaLArallalGdldeAral 23 
                  ++a++ +ll++G+++eA+++
  EEA22431.1 486 PRHAYGALLLEQGQFEEALDV 506
                 5899**************986 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 9.3
       TPR_4   2 rallaLArallalGdldeAr 21 
                 + l++L + l  l ++deAr
  EEA22431.1 528 WSLHGLVECLTTLKRYDEAR 547
                 66667777666666899997 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.3   0.0    0.0083       9.9       3      41 ..      40      78 ..      38      81 .. 0.77
   2 ?   -1.7   0.1       6.4   7.7e+03      29      43 ..     168     182 ..     166     184 .. 0.79
   3 ?   -1.5   0.1       5.4   6.4e+03       4      22 ..     394     412 ..     392     413 .. 0.77
   4 ?    0.4   0.0       1.4   1.6e+03       8      31 ..     448     471 ..     442     484 .. 0.77
   5 !    9.0   0.1    0.0023       2.8       5      24 ..     488     507 ..     486     509 .. 0.91

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0083
      TPR_14  3 allalaeallalGdpdeAiallrralalaPddaeawlll 41
                 + +++ +   + +++eA+++++ a++++P+   a+  l
  EEA22431.1 40 TWFDRGLIWTFAFNHEEAVNCFKNAIRDDPECTIAYWGL 78
                56777777777889****************987655444 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 6.4
      TPR_14  29 alaPddaeawlllaq 43 
                 + +Pdd+++  l+a+
  EEA22431.1 168 KNNPDDLDIAALYAD 182
                 668999999999886 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 5.4
      TPR_14   4 llalaeallalGdpdeAia 22 
                 ++a + a +alG+ +eA++
  EEA22431.1 394 HYAKGVASAALGRIEEAEN 412
                 5666777789999999985 PP

  == domain 4  score: 0.4 bits;  conditional E-value: 1.4
      TPR_14   8 aeallalGdpdeAiallrralala 31 
                 +e++++  + ++A  +lr+a +l+
  EEA22431.1 448 GEIEYRKSNIEQAFIYLRQATKLD 471
                 5677888899**********9875 PP

  == domain 5  score: 9.0 bits;  conditional E-value: 0.0023
      TPR_14   5 lalaeallalGdpdeAiall 24 
                  a++++ll++G+++eA++++
  EEA22431.1 488 HAYGALLLEQGQFEEALDVY 507
                 689**************998 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       5.9     7e+03      52      69 ..     170     187 ..     159     191 .. 0.57
   2 ?   -1.4   0.0       2.3   2.8e+03      57      77 ..     392     412 ..     386     418 .. 0.84
   3 ?   -0.2   0.0      0.98   1.2e+03      25      51 ..     443     470 ..     413     477 .. 0.82
   4 !   11.2   0.1   0.00027      0.33      26      76 ..     487     547 ..     453     551 .. 0.79

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 5.9
                 HHC-HHHHHHHHHHHHHT CS
      ANAPC3  52 nskslgcrylfAqcllkL 69 
                 n+ +l ++ l+A +l  L
  EEA22431.1 170 NPDDLDIAALYADALMNL 187
                 445555555555555444 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 2.3
                 HHHHHHHHHHHHTT-HHHHHH CS
      ANAPC3  57 gcrylfAqcllkLkkyeeAia 77 
                   +y ++ ++ +L+++eeA++
  EEA22431.1 392 MLHYAKGVASAALGRIEEAEN 412
                 567888899999******985 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 0.98
                 HHHHHHHHHHHTT-HHHHHHHHHCT.SH CS
      ANAPC3  25 dayllAlclylngqykrAyellrka.kl 51 
                 da+l ++  y+ ++ ++A+ +lr+a kl
  EEA22431.1 443 DAMLNGEIEYRKSNIEQAFIYLRQAtKL 470
                 6788888889999999999999998555 PP

  == domain 4  score: 11.2 bits;  conditional E-value: 0.00027
                 HHHHHHHHHHTT-HHHHHHHHHCT.SHHHC-H.......HHHHHHH..HHHHHTT-HHHHH CS
      ANAPC3  26 ayllAlclylngqykrAyellrka.klnsksl.......gcrylfA..qcllkLkkyeeAi 76 
                 +++++  l+++gq+++A++++++  +ln+  +       +++ l++  +cl  Lk+y+eA+
  EEA22431.1 487 RHAYGALLLEQGQFEEALDVYSTDlGLNDILPramqhpnNVWSLHGlvECLTTLKRYDEAR 547
                 6889999****************98877644455566699999999999**********97 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       7.5   8.9e+03      13      32 ..      38      57 ..      36      58 .. 0.77
   2 ?   -2.8   0.0       9.7   1.2e+04       1      10 [.      60      69 ..      60      70 .. 0.89
   3 ?    1.5   0.3       0.4   4.8e+02       7      25 ..     168     186 ..     166     199 .. 0.89
   4 ?   -2.2   0.0       6.4   7.7e+03      15      33 ..     393     411 ..     392     411 .. 0.86
   5 ?    5.0   0.0     0.032        38      16      33 ..     487     504 ..     485     505 .. 0.89
   6 ?    8.6   0.0    0.0022       2.6       9      33 ..     523     547 ..     522     547 .. 0.96

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 7.5
      TPR_17 13 adaynnLAelllknGdlmtA 32
                a  ++ ++ ++  + ++++A
  EEA22431.1 38 AQTWFDRGLIWTFAFNHEEA 57
                78899999999877666666 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 9.7
      TPR_17  1 lylkaleldP 10
                ++++a++ dP
  EEA22431.1 60 CFKNAIRDDP 69
                799****999 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.4
      TPR_17   7 eldPnnadaynnLAelllk 25 
                 +++P++ d   ++A +l +
  EEA22431.1 168 KNNPDDLDIAALYADALMN 186
                 79************99986 PP

  == domain 4  score: -2.2 bits;  conditional E-value: 6.4
      TPR_17  15 aynnLAelllknGdlmtAr 33 
                 +++ ++++ + +G+ ++A+
  EEA22431.1 393 LHYAKGVASAALGRIEEAE 411
                 58999999999**999996 PP

  == domain 5  score: 5.0 bits;  conditional E-value: 0.032
      TPR_17  16 ynnLAelllknGdlmtAr 33 
                  + ++ lll++G++++A+
  EEA22431.1 487 RHAYGALLLEQGQFEEAL 504
                 689*************96 PP

  == domain 6  score: 8.6 bits;  conditional E-value: 0.0022
      TPR_17   9 dPnnadaynnLAelllknGdlmtAr 33 
                 +Pnn+++++ L e+l  ++++++Ar
  EEA22431.1 523 HPNNVWSLHGLVECLTTLKRYDEAR 547
                 8**********************97 PP

>> HrpB1_HrpK  Bacterial type III secretion protein (HrpB1_HrpK)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   7.4e-05     0.088      25     103 ..     240     319 ..     227     337 .. 0.84
   2 ?   -2.9   0.0         4   4.8e+03      48      77 ..     444     473 ..     441     476 .. 0.79
   3 ?   -2.8   0.0       3.8   4.5e+03      52      67 ..     491     506 ..     488     509 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 7.4e-05
  HrpB1_HrpK  25 edtedaellLdalrvLrPevaeldllegvlliergrweeAlrl.LreveaeasgtpyakaLlAlcLaalrDeeWrayAee 103
                   +e+a ++ d lr L P +  l+ ++  l + +g+++ A+r   + ++a+++ +++  +L  + L+  ++ + r yA  
  EEA22431.1 240 PTPENALRVADHLRGLVPDAGHLNHMPTHLDVLCGDYQQAIRSnTQAIQADEKYFATSGSLRFYTLYRAHNYHFRLYAAM 319
                 5689999***********************************82456779999999999**9999999999999999975 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 4
  HrpB1_HrpK  48 dllegvlliergrweeAlrlLreveaeasg 77 
                 ++l+g +  +++++e A  +Lr+  +  ++
  EEA22431.1 444 AMLNGEIEYRKSNIEQAFIYLRQATKLDQE 473
                 578899999999999999999998766555 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 3.8
  HrpB1_HrpK  52 gvlliergrweeAlrl 67 
                 g ll+e+g++eeAl +
  EEA22431.1 491 GALLLEQGQFEEALDV 506
                 67999*******9865 PP

>> MIT  MIT (microtubule interacting and transport) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0      0.66   7.9e+02      19      31 ..      53      65 ..      51      67 .. 0.87
   2 ?    0.2   0.1      0.65   7.8e+02       2      16 ..     277     291 ..     274     294 .. 0.64
   3 ?    3.6   0.0      0.06        72       1      22 [.     457     478 ..     457     479 .. 0.92
   4 ?    1.9   0.0       0.2   2.4e+02      16      28 ..     496     508 ..     491     513 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.66
         MIT 19 nyeeAlelYkeal 31
                n eeA++++k+a+
  EEA22431.1 53 NHEEAVNCFKNAI 65
                789*******998 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.65
         MIT   2 dkAlelvkkAveeDn 16 
                 ++A+   ++A+++D+
  EEA22431.1 277 QQAIRSNTQAIQADE 291
                 566666666666666 PP

  == domain 3  score: 3.6 bits;  conditional E-value: 0.06
         MIT   1 ldkAlelvkkAveeDnagnyee 22 
                 +++A+ ++++A+++D++  y+e
  EEA22431.1 457 IEQAFIYLRQATKLDQELPYDE 478
                 689**************99987 PP

  == domain 4  score: 1.9 bits;  conditional E-value: 0.2
         MIT  16 nagnyeeAlelYk 28 
                 ++g++eeAl+ Y+
  EEA22431.1 496 EQGQFEEALDVYS 508
                 689*********7 PP

>> TPR_3  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.1       1.4   1.7e+03      15      21 ..     274     280 ..     273     281 .. 0.90
   2 ?   -2.9   0.0       6.1   7.3e+03      23      35 ..     385     395 ..     384     395 .. 0.82
   3 ?    1.2   0.2      0.32   3.8e+02      12      35 ..     452     473 ..     452     474 .. 0.84
   4 ?    8.9   0.2    0.0012       1.4       5      25 ..     488     508 ..     488     509 .. 0.95
   5 ?   -1.1   0.0       1.7     2e+03      15      21 ..     541     547 ..     540     549 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 1.4
                 T-HHHHH CS
       TPR_3  15 kkyqeAr 21 
                 ++yq+A+
  EEA22431.1 274 GDYQQAI 280
                 89****8 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 6.1
                 H..HHHHHHH-TT CS
       TPR_3  23 lfsYallaildke 35 
                 l+s  +++++ ++
  EEA22431.1 385 LYS--VTTTMLHY 395
                 888..**999886 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.32
                 HHTT-HHHHHHH..HHHHHHH-TT CS
       TPR_3  12 ynkkkyqeArelfsYallaildke 35 
                 y k ++++A  ++   ++++ld e
  EEA22431.1 452 YRKSNIEQAFIYLR--QATKLDQE 473
                 66779*******66..*****976 PP

  == domain 4  score: 8.9 bits;  conditional E-value: 0.0012
                 HHHHHHHHHTT-HHHHHHH.. CS
       TPR_3   5 ysyAaefynkkkyqeArelfs 25 
                 ++y+a +  +++++eA++++s
  EEA22431.1 488 HAYGALLLEQGQFEEALDVYS 508
                 69*****************88 PP

  == domain 5  score: -1.1 bits;  conditional E-value: 1.7
                 T-HHHHH CS
       TPR_3  15 kkyqeAr 21 
                 k+y+eAr
  EEA22431.1 541 KRYDEAR 547
                 9*****8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (582 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       409  (0.0228122); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.56u 0.26s 00:00:00.82 Elapsed: 00:00:00.42
# Mc/sec: 4118.03
//
Query:       EEA22432.1  [L=261]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (261 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       488  (0.0272185); expected 358.6 (0.02)
Passed bias filter:                      286  (0.0159518); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.25s 00:00:00.67 Elapsed: 00:00:00.41
# Mc/sec: 1917.21
//
Query:       EEA22433.1  [L=62]
Description: ribosomal S30/ubiquitin fusion [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.2e-28   97.7   7.3    3.5e-28   97.6   7.3    1.0  1  Ribosomal_S30  Ribosomal protein S30


Domain annotation for each model (and alignments):
>> Ribosomal_S30  Ribosomal protein S30
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.6   7.3   1.9e-32   3.5e-28       1      57 [.       3      60 ..       3      61 .. 0.97

  Alignments for each domain:
  == domain 1  score: 97.6 bits;  conditional E-value: 1.9e-32
                   XTBX-STTTTHHHHHS-------------THHHHHHHHHHHTTS.SS--SSSSS-S-- CS
  Ribosomal_S30  1 kvhGsLarAGKVrnqTPKveKqekkKkptGRakkRlqYnrRfvn.vvvggkkkkgpns 57
                   kvhGsLarAGKV+  TPKv+Kqek+K+p+GRakkRl Y+rRfvn +++ggk+k++pn+
     EEA22433.1  3 KVHGSLARAGKVKAATPKVDKQEKPKQPKGRAKKRLVYTRRFVNvTLTGGKRKMNPNP 60
                   9*******************************************999999******96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (62 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       436  (0.0243181); expected 358.6 (0.02)
Passed bias filter:                      267  (0.0148921); expected 358.6 (0.02)
Passed Vit filter:                         9  (0.00050198); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.36u 0.24s 00:00:00.60 Elapsed: 00:00:00.41
# Mc/sec: 457.95
//
Query:       EEA22434.1  [L=150]
Description: hypothetical protein PMAA_090630 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    7.7e-06   26.1   0.0    1.2e-05   25.5   0.0    1.3  1  Glyoxalase  Glyoxalase/Bleomycin resistance protein/Dioxygena


Domain annotation for each model (and alignments):
>> Glyoxalase  Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.5   0.0   6.6e-10   1.2e-05       1     123 [.      11     125 ..      11     130 .. 0.88

  Alignments for each domain:
  == domain 1  score: 25.5 bits;  conditional E-value: 6.6e-10
                 EEEEEEEEESHHHHHHHHHHHHHTSEEEEEEEEEESTEEEEEEEEETTTSEEEEEEEECCTTSCTHHCCBSCTSEEEEEEEEEHCHHHHHHHHHHHTTG CS
  Glyoxalase   1 gidhvallvgdleksldFYtkvLGfklvkktdnteeteglriaffhaggghielvlneapsgaakhvkkieetvhhvafialdvedvgkaldrlkeagv 99 
                 gi+h+ l+++d+ k+ +FYt+++ f+     d  + +++l +  ++     ++l ++ +p+ a+ ++     +   v + +++  d++++   ++++gv
  EEA22434.1  11 GIHHLKLPATDIRKTEAFYTRIFPFESCPNLDHYTRDGKLFAVLLTYKLAGLMLEIRYNPEQAKIQQ-----GWDPVTWSVDSRKDLEEWGVWFDANGV 104
                 79**************************999976666777777777777777777777777777777.....5799*********************** PP

                 EEEEEEECHHCTEEEEEEEEETTS CS
  Glyoxalase 100 kvvaepgrhyfgalysfyfrDpdG 123
                 + +++++ ++   +    ++DpdG
  EEA22434.1 105 SHSKVLKGMKGWVMA---AEDPDG 125
                 ******888888888...*****9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (150 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       320  (0.0178482); expected 358.6 (0.02)
Passed bias filter:                      248  (0.0138323); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.48
# Mc/sec: 934.89
//
Query:       EEA22435.1  [L=389]
Description: alpha-ketoglutarate-dependent taurine dioxygenase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.3e-61  206.8   0.3    6.5e-61  206.5   0.3    1.1  1  TauD      Taurine catabolism dioxygenase TauD, TfdA family


Domain annotation for each model (and alignments):
>> TauD  Taurine catabolism dioxygenase TauD, TfdA family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  206.5   0.3   3.6e-65   6.5e-61       2     268 .]      89     354 ..      88     354 .. 0.93

  Alignments for each domain:
  == domain 1  score: 206.5 bits;  conditional E-value: 3.6e-65
        TauD   2 vkpltpkfgae..gvdlsdleslddelkeelrellaeygvvvfrgfplspeqqlefarrfGplygtpgrgtntkygevld....vssvyesadianlay 94 
                 v +lt+++g+e  g++l d   l++++++el  l+ae+ vv+fr+++lsp+qq+++ + fG+++ +p+ g+ +  ++v +     ++    +  +n  +
  EEA22435.1  89 VIHLTRHIGTEivGLQLKD---LTNQQRDELALLIAERSVVFFRDQDLSPQQQKALGEHFGEIEVHPQVGQVPGVPGVTVlwpaLQA---VEREPNFRK 181
                 5689*******99999999...78888*****************************************************9666444...444444333 PP

        TauD  95 ttll..wHtDlsylesppgiqlLhcleapatGGetpfvDgraaynaLpeelpellegltavrvyyhyrggglrteqelpavdkhprtghpvvrthpvlt 191
                 t+    wH+Dl ++++p+gi++Lh  ++p+ GG+t++++g++ay++L+++ +++++g ta+++ +h++      + +++a+ ++ +++hp+vrthp  t
  EEA22435.1 182 TGGAstWHSDLVHESQPAGITHLHNDTIPSVGGDTLWASGYSAYEKLSPSFRKFIDGKTAIYRSAHSYL----DRGNPQAGPQFVEREHPLVRTHPA-T 275
                 444456***************************************************************....99*********************6.* PP

        TauD 192 grkallvnppfatrieglgtpeskelldaleelled.peftyrfqwqeGdlvifdNrrvlHgrt.afdeg.eeRhllrcy 268
                 g+kal vn+ ++ ri+gl+++es+ +l +l++++e+ p++++rf+w + + +++dNr + H ++ ++ eg e+Rh  r++
  EEA22435.1 276 GWKALWVNRSMTVRIVGLDKAESDLILGYLYDVYERsPDIQVRFKWSPKSSALWDNRITIHNASwDY-EGlEPRHGTRVT 354
                 ************************************77*****************************.77699**99986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (389 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       340  (0.0189637); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.67u 0.33s 00:00:01.00 Elapsed: 00:00:00.57
# Mc/sec: 2063.91
//
Query:       EEA22436.1  [L=488]
Description: FAD dependent oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.7e-39  135.7   0.0    3.5e-20   71.9   0.0    3.1  3  FMO-like        Flavin-binding monooxygenase-like
    1.5e-17   63.9   0.1    4.8e-12   45.8   0.0    2.2  2  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
    2.1e-14   53.5   0.0    8.2e-14   51.5   0.0    1.9  1  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    2.1e-11   44.1   5.4    2.5e-06   27.3   0.9    3.5  4  DAO             FAD dependent oxidoreductase
    2.3e-08   34.1   0.2    6.4e-08   32.7   0.0    1.9  1  NAD_binding_8   NAD(P)-binding Rossmann-like domain
    3.3e-07   29.8   0.1     0.0019   17.4   0.0    3.1  3  K_oxygenase     L-lysine 6-monooxygenase (NADPH-requiring)
    1.2e-06   28.6   3.1    5.2e-06   26.5   0.5    3.2  3  NAD_binding_9   FAD-NAD(P)-binding
      3e-06   26.9   0.0     0.0043   16.7   0.0    2.5  2  ApbA            Ketopantoate reductase PanE/ApbA
    1.4e-05   25.5   2.1     0.0002   21.9   0.4    2.8  2  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
    7.8e-05   22.1   0.1    0.00091   18.6   0.0    2.1  2  Amino_oxidase   Flavin containing amine oxidoreductase
    0.00021   21.4   0.9       0.02   15.0   0.1    2.8  2  Shikimate_DH    Shikimate / quinate 5-dehydrogenase
    0.00032   19.5   1.5    0.00072   18.4   0.9    1.7  2  HI0933_like     HI0933-like protein
     0.0008   19.3   0.0     0.0015   18.4   0.0    1.4  1  3HCDH_N         3-hydroxyacyl-CoA dehydrogenase, NAD binding 
     0.0025   17.1   1.1      0.013   14.8   0.3    2.2  3  FAD_binding_3   FAD binding domain
     0.0035   17.5   0.0     0.0096   16.1   0.0    1.7  1  NAD_binding_2   NAD binding domain of 6-phosphogluconate dehy
     0.0042   16.2   0.0     0.0082   15.3   0.0    1.5  1  FAD_binding_2   FAD binding domain
     0.0047   16.2   0.5      0.031   13.5   0.3    2.1  2  Thi4            Thi4 family
  ------ inclusion threshold ------
      0.012   15.0   0.0      0.019   14.3   0.0    1.3  1  FAD_oxidored    FAD dependent oxidoreductase
      0.042   13.1   2.7      0.071   12.4   1.0    2.0  2  AlaDh_PNT_C     Alanine dehydrogenase/PNT, C-terminal domain
      0.063   12.3   1.6       0.12   11.5   1.6    1.4  1  GIDA            Glucose inhibited division protein A
      0.074   13.6   0.1        9.5    6.9   0.0    2.7  2  F420_oxidored   NADP oxidoreductase coenzyme F420-dependent
       0.18   11.4   0.1       0.38   10.3   0.1    1.5  1  IlvN            Acetohydroxy acid isomeroreductase, NADPH-bin
       0.18   11.8   0.0        1.2    9.0   0.1    2.2  2  NAD_Gly3P_dh_N  NAD-dependent glycerol-3-phosphate dehydrogen
       0.22   12.0   2.2        2.6    8.5   0.0    3.0  3  NAD_binding_7   Putative NAD(P)-binding


Domain annotation for each model (and alignments):
>> FMO-like  Flavin-binding monooxygenase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.5   0.0   6.8e-10   5.1e-07       3      45 ..      10      52 ..       8      60 .. 0.94
   2 !   71.9   0.0   4.7e-23   3.5e-20      57     218 ..      96     266 ..      84     278 .. 0.84
   3 !   31.4   0.0   8.8e-11   6.6e-08     314     441 ..     315     453 ..     309     465 .. 0.71

  Alignments for each domain:
  == domain 1  score: 28.5 bits;  conditional E-value: 6.8e-10
    FMO-like  3 kvaviGaGvsGlasikccleegleptcfersddiGGlwrfken 45
                kvaviGaG+sG+++    l+ gle t fer ++ GG+w ++++
  EEA22436.1 10 KVAVIGAGISGVVTAAHLLNAGLEVTVFERNKEAGGVWLYDDR 52
                9*************************************99875 PP

  == domain 2  score: 71.9 bits;  conditional E-value: 4.7e-23
    FMO-like  57 vvsnsskemscfsdfplpedypnflhnsklleylklfakefdllkyiqfkttvcsvkkrpdfst.sGqw......evvtekegkkesavfdavmvctGh 148
                 +  n+s  ++  +    p++ p+f+ +  + ey+   +++ ++     f ++v++++k ++ s+    w      + + e ++++++++fdav+v +Gh
  EEA22436.1  96 LRNNVSTPLMRVTLNAWPDKTPDFVSHRVMNEYIIDTSRKSGVHGVTLFGAKVTNIEKVNELSKwQVSWtelredDETGEVNEQEKNDLFDAVVVASGH 194
                 556777777777777889*****************************************9998634467222222344566778999************ PP

    FMO-like 149 hvnphlpl.esfpGiekfk.GqyfhsrdykepevfkgkrvlviGlGnsggdiavelsrtaeqvllstrsGsw 218
                 +  p +p    +  i+++   +++hs+ y++p+ + gk vl+iG G s++dia el   a++++ str+  +
  EEA22436.1 195 YHAPRIPNiTGLAYIKRLWpLRVLHSKGYRRPDEYAGKNVLLIGGGVSSTDIARELGPVAKNIYQSTRNSPY 266
                 *******6255777777542599*********************************************9765 PP

  == domain 3  score: 31.4 bits;  conditional E-value: 8.8e-11
    FMO-like 314 dgtveedidvvifatGytfafpfl.............ees.lvkveknkvslykkvfpanlekptlaiiGliqplGsilptvelqarwavrvlkGlkkl 398
                 + ++ edid +i +tGy f+ pfl              ++ lv   ++   l+k +f   +  ptla +G+     + ++  e qa  +++++ G+++l
  EEA22436.1 315 QDSTIEDIDYIIVCTGYYFTLPFLrrlheddtkpteaSDTvLVTDGTQVHNLHKDIFY--IPDPTLAFVGV-PFYTATFTLFEFQAIAVTEIFAGIARL 410
                 457789*****************96665322111111011112222233356777774..5689******5.678899********************* PP

    FMO-like 399 psekelleeitekkekkakrfgesksktiqtdyiayldelaal 441
                 ps +++ +e  +k e+k     + + k  +  y++ l +  ++
  EEA22436.1 411 PSGSNMRDEYRAKIEQKGVGRNFHSLKGEEEGYVQELLDWINF 453
                 *************999876666666666666676666555554 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   7.6e-06    0.0057     165     199 ..       9      43 ..       5      79 .. 0.78
   2 !   45.8   0.0   6.4e-15   4.8e-12     115     284 ..     175     347 ..     146     369 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 7.6e-06
  Pyr_redox_3 165 qkvvViGgknSavDaAlelvrkgaeVtvvtrgsei 199
                  +kv+ViG++ S+v +A +l ++g eVtv+ r++e 
   EEA22436.1   9 DKVAVIGAGISGVVTAAHLLNAGLEVTVFERNKEA 43 
                  79*****************************9874 PP

  == domain 2  score: 45.8 bits;  conditional E-value: 6.4e-15
  Pyr_redox_3 115 evetsketyeAkkviiAtGefdkPnklnipGee..k.....lvkhyskvkefhkyagqkvvViGgknSavDaAlelvrkgaeVtvvtrgseiekeesd 205
                  ev+ ++++   + v++A G ++ P+ +ni G    k      v h++ ++ +++yag++v+ iGg+ S+ D+A el    +++   tr+s+     +d
   EEA22436.1 175 EVNEQEKNDLFDAVVVASGHYHAPRIPNITGLAyiKrlwplRVLHSKGYRRPDEYAGKNVLLIGGGVSSTDIARELGPVAKNIYQSTRNSP-----YD 267
                  5555555555578******************87331233334669999**************************************99985.....67 PP

  Pyr_redox_3 206 psyslkpdienrleelvkeek.ikvlfnaevkeikekeeeykvktedgkkvev.kddvvlatGykpdlsflkkslfelded 284
                     ++ pd+  r++e+   e      +++ +++ ++   ++++k++d++++ +  d ++++tGy  +l fl+  l e+d++
   EEA22436.1 268 LTEKMLPDNGTRVAEIEFFEItSATRTEEPLTAESHLPIKVHLKSTDQDSTIEdIDYIIVCTGYYFTLPFLR-RLHEDDTK 347
                  778999*********8664420233344455666666667777766666655515556666**********9.55554433 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.5   0.0   1.1e-16   8.2e-14       2     274 ..      10     373 ..       9     379 .. 0.71

  Alignments for each domain:
  == domain 1  score: 51.5 bits;  conditional E-value: 1.1e-16
                  SEEEE--SHHHHHHHHHHHHHTS-EEEEE....TTHCHHHCSHHHHCHHHHHHHHHHHHH...................................... CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxx...................................... RF
  Pyr_redox_2   2 dvvviGgGpAGlaaaltlaqagakvtlve....legtclnggcllskallgvaedaeias...................................... 57 
                  +v+viG+G+ G+ +a +l +ag++vt++e    ++g +l+++  + + +  + ++ e ++                                      
   EEA22436.1  10 KVAVIGAGISGVVTAAHLLNAGLEVTVFErnkeAGGVWLYDDRRPIESIYPATRPSEAEQagdyeeiqefdrlvlehappgpcyvglrnnvstplmrv 107
                  89**************************88888777777777777555555555555444567777888999************************** PP

                  ......................................HHHHCHHHHCCCCHCCTCEEEEESCEEEEETEEEC......................TCE CS
                  ......................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......................xxx RF
  Pyr_redox_2  58 ......................................evvkklnqgielllgeevvkidpgkkkvklekkke......................gde 95 
                                                                                  kv+  +k++                      ++e
   EEA22436.1 108 tlnawpdktpdfvshrvmneyiidtsrksgvhgvtlfgA-------------------------KVTNIEKVNelskwqvswtelreddetgevnEQE 180
                  ************999777777776655555543322220.........................2222222222333333334444455566877888 PP

                  EEEEESEEEE---E..EE-BCTCTTC...TTBEECCSECHHHHHHCCSS-T.SEEEEES-SHHHHHHHHHHHHHT-EEEEEESSSSSSTTS-HHHHHH CS
                  xxxxxxxxxxxxxx..xxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  96 ekiaydklvlAtGs..sprdlgipGv..aenvgklvrtldsaealklkllp.krivvvGgGyiGvElAaalaklgkevtlveardrllraldkelsaa 188
                  ++  +d++v+A+G    pr+++i G+   +  + l r l+s+ + + ++   k+++ +GgG+ ++++A +l  ++k+++    r+ ++        + 
   EEA22436.1 181 KNDLFDAVVVASGHyhAPRIPNITGLayIKRLWPL-RVLHSKGYRRPDEYAgKNVLLIGGGVSSTDIARELGPVAKNIY-QSTRNSPY--------DL 268
                  89999********66699999****9664444555.9999999999999889*******************99999886.45555555........34 PP

                  HHHHHHHTTEEEEESCEEEEEEETTE...............EEEEEETTSCEEEESEEEE-S-EEES-HHCS...HCCT-EEEETTEEE--TTSBE.S CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxx...............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxx.x RF
  Pyr_redox_2 189 leealekeGvevklgtsvkeidgnge...............klevvledgeeidadlvvvavGvrpstelle...eklglelderggivvdeflrt.n 267
                   e+ l ++G +v  + ++ ei++ ++               +l+ +++d + +d d+++v++G+    ++l    e++  +++  + ++v +  ++ n
   EEA22436.1 269 TEKMLPDNGTRVA-EIEFFEITSATRteepltaeshlpikvHLKSTDQDSTIEDIDYIIVCTGYYFTLPFLRrlhEDDTKPTEASDTVLVTDGTQVhN 365
                  4444444444444.22222333333333344444457673333355555555************9999988888888888888888887777777745 PP

                  .STTEEE- CS
                  .xxxxxxx RF
  Pyr_redox_2 268 .vpgiyai 274
                   +++i+ i
   EEA22436.1 366 lHKDIFYI 373
                  78888876 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.9   3.4e-09   2.5e-06       1      35 [.      10      45 ..      10      49 .. 0.94
   2 !    7.1   0.0    0.0047       3.5     160     206 ..     140     199 ..     120     226 .. 0.66
   3 ?   -2.2   0.1       3.3   2.4e+03       2      18 ..     234     250 ..     233     263 .. 0.86
   4 !    9.7   0.0   0.00075      0.56     183     256 ..     309     386 ..     247     397 .. 0.68

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 3.4e-09
                EEEEECTSHHHHHHHHHHHHTT..EEEEESSSSTTSS CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..Vtllekgdiagsg 35
                +v++iG+Gi G+ tA +L  +g  Vt++e++++ag g
  EEA22436.1 10 KVAVIGAGISGVVTAAHLLNAGleVTVFERNKEAG-G 45
                59****************999**********9998.5 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0047
                 T-EEEESECEEEEEEEE..TCEEEEE...........EECTEEE.E......EEEEEEE--GGGHH.H CS
         DAO 160 Gveilegtevtgleeed..gkvwgve...........rttpgen.d......aadavVnaaGawsd.l 206
                 Gv+ l+g++vt++e+ +   k w+v            +     + +        davV+a G++    
  EEA22436.1 140 GVT-LFGAKVTNIEKVNelSK-WQVSwtelreddetgE-----VnEqekndlF-DAVVVASGHYHApR 199
                 444.45569999987555433.7777777776543331.....3224455545.89*******95443 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 3.3
                 EEEECTSHHHHHHHHHH CS
         DAO   2 vviiGGGiiGlstAyeL 18 
                 v+ iGGG+    +A+eL
  EEA22436.1 234 VLLIGGGVSSTDIAREL 250
                 778******99999998 PP

  == domain 4  score: 9.7 bits;  conditional E-value: 0.00075
                 E..EECT.EEEEEEEEEEE--GGGHH..HHHTT.CTTTSEEEEEEEEEEEEEECCTHSTGSGCSEEEEEEEETTTTEEEE CS
         DAO 183 e..rttp.gendaadavVnaaGawsd..llgll.keldlpispvrgqvlvlkplseklvspaailpvpetdddgrgvyvt 256
                 +   t +  +++ +d++++++G + +  +l++l ++  +p + +  +vlv++ ++  ++ ++ i+ +p+++  + gv ++
  EEA22436.1 309 HlkSTDQdSTIEDIDYIIVCTGYYFTlpFLRRLhEDDTKP-TEASDTVLVTDGTQV-HNLHKDIFYIPDPTLAFVGVPFY 386
                 24333332333457**********9985555552333245.677888888866544.66667899998877777777665 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.7   0.0   8.6e-11   6.4e-08       1      37 [.      13      49 ..      13      80 .. 0.81

  Alignments for each domain:
  == domain 1  score: 32.7 bits;  conditional E-value: 8.6e-11
                   EE--SHHHHHHHHHHHCCTEEEEEE-SSSSSSGGG-E CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekrdrlGGraas 37
                   ++GaG+sG v+A++L +ag++v+++e++   GG +  
     EEA22436.1 13 VIGAGISGVVTAAHLLNAGLEVTVFERNKEAGGVWLY 49
                   8*******************************97654 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.1      0.04        30     191     215 ..       8      32 ..       3      43 .. 0.75
   2 !   17.4   0.0   2.6e-06    0.0019     113     210 ..     142     250 ..     118     265 .. 0.75
   3 ?    5.0   0.0     0.015        11     311     341 ..     303     332 ..     266     333 .. 0.68

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.04
  K_oxygenase 191 kkriaVvGsGqSaaeifedllrrqk 215
                   +++aV+G+G S+   + +ll+   
   EEA22436.1   8 IDKVAVIGAGISGVVTAAHLLNAGL 32 
                  57899*****999988888887644 PP

  == domain 2  score: 17.4 bits;  conditional E-value: 2.6e-06
  K_oxygenase 113 vrfgeeveevepdeeeee...elltveskdaegeee....elearnlvlgvG..tepkiPev.....leklegkervvHsseylerkeellakkriaV 196
                    fg++v+++e ++e ++   +  +++ +d++ge +    +    ++v++ G    p iP++     +++l    rv+Hs+ y +    + a+k+++ 
   EEA22436.1 142 TLFGAKVTNIEKVNELSKwqvSWTELREDDETGEVNeqekNDLFDAVVVASGhyHAPRIPNItglayIKRLW-PLRVLHSKGYRRPD--EYAGKNVLL 236
                  569999999999998666534446666666666554111144456799*9997789****983322234444.489******98876..89******* PP

  K_oxygenase 197 vGsGqSaaeifedl 210
                  +G+G S  +i+++l
   EEA22436.1 237 IGGGVSSTDIAREL 250
                  **********9988 PP

  == domain 3  score: 5.0 bits;  conditional E-value: 0.015
  K_oxygenase 311 kgeveltlrneesgeeetlevdavvlATGYr 341
                  +  ++++l+   +++++ +++d+++++TGY 
   EEA22436.1 303 HLPIKVHLKS-TDQDSTIEDIDYIIVCTGYY 332
                  2245555555.445667899**********5 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.5   0.5     7e-09   5.2e-06       1     155 [.      12     194 ..      12     195 .. 0.65
   2 ?   -2.9   0.1       8.2   6.1e+03       2      16 ..     236     250 ..     235     254 .. 0.88
   3 ?   -2.1   0.0       4.5   3.4e+03     138     154 ..     314     330 ..     301     331 .. 0.72

  Alignments for each domain:
  == domain 1  score: 26.5 bits;  conditional E-value: 7e-09
  NAD_binding_9   1 aivGaGprGlavlerLlarakkkspleitlfdpsepgagrvwrtdqseelllNvpasemslftddp.....ptfaeWlrerga............. 78 
                    a++GaG++G+ ++++Ll+       le+t+f++++   g+vw  d+ +     +pa + s  ++       ++f++ + e++              
     EEA22436.1  12 AVIGAGISGVVTAAHLLNA-----GLEVTVFERNKEA-GGVWLYDDRRPIESIYPATRPSEAEQAGdyeeiQEFDRLVLEHAPpgpcyvglrnnvs 101
                    89***************99.....6********9997.8999999877766667777777665544888898888887777777888877776665 PP

  NAD_binding_9  79 ...lee....aeeldpddfvpRalyGrYlrdlfeellarlpegvtvevhraevvdleera......dgq.avll........adgaslaadaVvLA 152
                         +    a   +  dfv+ +++ +Y+ d+ ++          v+++ a+v+++e+ +       ++ ++++        +++++  +daVv+A
     EEA22436.1 102 tplM-RvtlnAWPDKTPDFVSHRVMNEYIIDTSRKSGVH-----GVTLFGAKVTNIEKVNelskwqVSWtELREddetgevnEQEKNDLFDAVVVA 191
                    5541.1454545556678889999999988887775432.....3566666666666655221111111112222211111133344578888888 PP

  NAD_binding_9 153 lGh 155
                     Gh
     EEA22436.1 192 SGH 194
                    888 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 8.2
  NAD_binding_9   2 ivGaGprGlavlerL 16 
                    ++G+G++ + ++++L
     EEA22436.1 236 LIGGGVSSTDIAREL 250
                    79*****99999877 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 4.5
  NAD_binding_9 138 ladgaslaadaVvLAlG 154
                     +d +  ++d++++++G
     EEA22436.1 314 DQDSTIEDIDYIIVCTG 330
                    23444469********9 PP

>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   5.7e-06    0.0043       1      70 [.      11      80 ..      11      84 .. 0.79
   2 !    7.6   0.0    0.0037       2.8      48      87 ..     300     340 ..     278     383 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 5.7e-06
                EEEES-SHHHHHHHHHHHHHTHCEEEE-SCHHHHHHHHHCEEEEETT.CEEEEEECEEECCH....SCCCCS-ES CS
        ApbA  1 iailGaGaiGsllaakLakagadvtlilrsrrlealkknGlrltseg.geeilrppealsae....ekselepid 70
                +a++GaG  G + aa+L +ag +vt+  r++     +  G+ l++++   e ++p + +s++    + +e++++d
  EEA22436.1 11 VAVIGAGISGVVTAAHLLNAGLEVTVFERNK-----EAGGVWLYDDRrPIESIYPATRPSEAeqagDYEEIQEFD 80
                69****************************9.....678888888888777777777766665556555555555 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0037
                 CEEEEEECEEECCH.SCCCCS-ESEEEE-SSGGGHHHHHHH CS
        ApbA  48 geeilrppealsae.ekselepidlvivtvKayqteealee 87 
                  e +l+ +++l ++ ++s +e+id++iv++  y t   l++
  EEA22436.1 300 AESHLPIKVHLKSTdQDSTIEDIDYIIVCTGYYFTLPFLRR 340
                 4556666666666688899***********88877766655 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.9   0.4   2.6e-07    0.0002       1      34 [.      10      43 ..      10      51 .. 0.93
   2 ?    2.0   0.0      0.41   3.1e+02       2      22 ..     234     254 ..     233     264 .. 0.80

  Alignments for each domain:
  == domain 1  score: 21.9 bits;  conditional E-value: 2.6e-07
                EEEEECSSHHHHHHHHHHHHTTSEEEEEESSSSS CS
   Pyr_redox  1 kvvvvGgGyiglElAgalaelgkkVtvversdkl 34
                kv+v+G+G +g+  A+ l + g +Vtv+er+++ 
  EEA22436.1 10 KVAVIGAGISGVVTAAHLLNAGLEVTVFERNKEA 43
                79****************************9876 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.41
                 EEEECSSHHHHHHHHHHHHTT CS
   Pyr_redox   2 vvvvGgGyiglElAgalaelg 22 
                 v+ +GgG++  + A +l   +
  EEA22436.1 234 VLLIGGGVSSTDIARELGPVA 254
                 889***********9985554 PP

>> Amino_oxidase  Flavin containing amine oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0   1.2e-06   0.00091       1      28 [.      18      45 ..      18      54 .. 0.95
   2 ?    1.0   0.0      0.28   2.1e+02     241     266 ..     167     198 ..     133     210 .. 0.62

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 1.2e-06
                   HHHHHHHHHHHHTTEEEEEEESSSSSBT CS
  Amino_oxidase  1 laGLaaArqLlsaGfdVtvlEardrvGG 28
                   ++G ++A +Ll+aG++Vtv+E +  +GG
     EEA22436.1 18 ISGVVTAAHLLNAGLEVTVFERNKEAGG 45
                   8**************************9 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.28
                    EEEEETTSTEE......EESEEEE-S-HHHHH CS
  Amino_oxidase 241 vtvtledgevv......eaDaVvvTvplgvlk 266
                     +   e+gev+       +DaVvv++  +++ 
     EEA22436.1 167 LREDDETGEVNeqekndLFDAVVVASGHYHAP 198
                    22222344444555556********9998876 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.1   2.7e-05      0.02      13      47 ..       9      42 ..       3      45 .. 0.92
   2 ?    4.0   0.0     0.066        49       9      31 ..     228     250 ..     222     322 .. 0.86

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 2.7e-05
                  -EEEEES-SHHHHHHHHHHHCCT-CEEEEEESSHH CS
  Shikimate_DH 13 kkvlliGaGemaelvakhLlakgvkkvvvaNRtle 47
                   kv +iGaG  +  +a hLl++g++ v+v+ R+ e
    EEA22436.1  9 DKVAVIGAGISGVVTAAHLLNAGLE-VTVFERNKE 42
                  699*********************9.******987 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.066
                   ..TT-EEEEES-SHHHHHHHHHH CS
  Shikimate_DH   9 slkekkvlliGaGemaelvakhL 31 
                   ++++k+vlliG G  ++ +a+ L
    EEA22436.1 228 EYAGKNVLLIGGGVSSTDIAREL 250
                   6789***************9998 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.9   9.7e-07   0.00072       2      36 ..      10      44 ..       9      46 .. 0.96
   2 ?   -1.5   0.0         1   7.8e+02     126     169 ..     158     199 ..     146     201 .. 0.73

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 9.7e-07
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SSSSS- CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVlllekakklg 36
                 +v+viG+G +G+ +A+++ ++g +V+++e++k++g
   EEA22436.1 10 KVAVIGAGISGVVTAAHLLNAGLEVTVFERNKEAG 44
                 79*****************************9987 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1
                  EE-S--EEEEECETTE.EEEEE.TTEEEEESEEEE----SS-GG CS
  HI0933_like 126 lrletevksvekeedgkfrvktkseeeleadklvlAtGGlSiPk 169
                   + + +++++++ +d++ +v+  +e++   d++v+A+G   +P+
   EEA22436.1 158 SKWQVSWTELRE-DDETGEVNE-QEKNDLFDAVVVASGHYHAPR 199
                  556778888854.555588888.788888999****99877776 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.0     2e-06    0.0015       1      34 [.      10      43 ..      10      63 .. 0.96

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 2e-06
                EEEEE--SCCHHHHHHHHHHTT-EEEEE-S-HHH CS
     3HCDH_N  1 kvaviGaGtmGagiaavfasagleVvlvdiseea 34
                kvaviGaG+ G   aa +++agleV+++++++ea
  EEA22436.1 10 KVAVIGAGISGVVTAAHLLNAGLEVTVFERNKEA 43
                79****************************9986 PP

>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.3   1.7e-05     0.013       3      35 ..      10      42 ..       9      44 .. 0.94
   2 ?   -3.1   0.0       4.8   3.6e+03     197     248 ..     117     180 ..     107     199 .. 0.59
   3 ?    0.0   0.0      0.52   3.9e+02      96     164 ..     258     331 ..     217     355 .. 0.73

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 1.7e-05
                   EEEEE--SHHHHHHHHHHHHTTHHEEEEESSSS CS
  FAD_binding_3  3 dVlIVGaGpaGlmlallLseaGvrvvlvekrst 35
                   +V+++GaG +G+++a  L +aG +v++ e+ ++
     EEA22436.1 10 KVAVIGAGISGVVTAAHLLNAGLEVTVFERNKE 42
                   69***************************9875 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 4.8
                    CCCTTC....CEEEEECCTTEE........EEEECCETEEEEEEEEECCE-GGGSCCCHHHHHH CS
  FAD_binding_3 197 sdivep....lvlilsaesrgv........mviPlentlerfyvqvearaekeersekfteeev 248
                    +d+v++    +++i  + ++gv         v   e+  e   +qv++++ +e++++ + +e+ 
     EEA22436.1 117 PDFVSHrvmnEYIIDTSRKSGVhgvtlfgaKVTNIEKVNELSKWQVSWTELREDDETGEVNEQE 180
                    5556666663444444444444666666665555555555556777777777666554444444 PP

  == domain 3  score: 0.0 bits;  conditional E-value: 0.52
                    ST-CEE--HHHHHHHHHHHHHHHT.EEET...CSEEEECCEECCCCCCCEEEECCTTEEEEEE.EEEEEE--GT CS
  FAD_binding_3  96 pervtvypqteleriLvehaeerg.lqvr...fktevesleqdeegvtaevrdketgeeetvr.akYlvGaDGg 164
                    ++++ + p + +e++L ++ ++ + +++     +t++e  +  e++   +v  k+t++++t++  +Y++ + G+
     EEA22436.1 258 YQSTRNSPYDLTEKMLPDNGTRVAeIEFFeitSATRTEEPLTAESHLPIKVHLKSTDQDSTIEdIDYIIVCTGY 331
                    56666777888888888885554444433000334444444444444455668999999999637999999885 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0   1.3e-05    0.0096       1      42 [.      10      51 ..      10      69 .. 0.83

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 1.3e-05
                   EEEEE--SHHHHHHHHHHHHTT-EEEEE-SSHHHHHHHHHTT CS
  NAD_binding_2  1 kigfiGlGvMGsnmalnllkagykvavynrtkekveelvaeg 42
                   k+++iG G+ G   a +ll+ag +v+v++r+ke+   ++ + 
     EEA22436.1 10 KVAVIGAGISGVVTAAHLLNAGLEVTVFERNKEAGGVWLYDD 51
                   69*****************************99866665555 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   1.1e-05    0.0082       2      36 ..      11      45 ..      10      88 .. 0.90

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 1.1e-05
                   EEEE--SHHHHHHHHHHHHTTT-EEEEESSSGGGS CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGlkvavvekeqefgg 36
                   v ViG+G++G + A+ + +aGl+v+v e  +e gg
     EEA22436.1 11 VAVIGAGISGVVTAAHLLNAGLEVTVFERNKEAGG 45
                   89***************************999665 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.3   4.2e-05     0.031      19      59 ..      10      48 ..       6      50 .. 0.85
   2 ?    0.1   0.0      0.53     4e+02      11      37 ..     225     251 ..     216     257 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 4.2e-05
                EEEEE--SHHHHHHHHHHHHCTTS-EEEEESSSS--TTTTT CS
        Thi4 19 DvvivGaGssGLtaayylakkpdlkvailersvspGGGawl 59
                 v+++GaG sG+ +a  l ++ +l+v+++er+    GG+wl
  EEA22436.1 10 KVAVIGAGISGVVTAAHLLNA-GLEVTVFERNKEA-GGVWL 48
                589********9998888888.9********9766.56775 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.53
                 HHHHHTEEEEEEE--SHHHHHHHHHHH CS
        Thi4  11 dllkyaesDvvivGaGssGLtaayyla 37 
                   ++ya  +v+++G+G s    a+ l+
  EEA22436.1 225 RPDEYAGKNVLLIGGGVSSTDIARELG 251
                 5689**************999999876 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   2.6e-05     0.019       2      38 ..      11      47 ..      10      74 .. 0.93

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2.6e-05
  FAD_oxidored  2 vvVvGGgpaGvaAAiaAaraGakvlLveergvlGGll 38
                  v V+G+g++Gv+ A    +aG +v + e+++  GG  
    EEA22436.1 11 VAVIGAGISGVVTAAHLLNAGLEVTVFERNKEAGGVW 47
                  89*********************************75 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   1.0   9.5e-05     0.071      30      62 ..      10      42 ..       3      46 .. 0.93
   2 ?   -1.0   0.0       1.2   8.6e+02      30      42 ..     233     245 ..     229     262 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 9.5e-05
                 EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHH CS
  AlaDh_PNT_C 30 kvlviGgGvaGlqAiatakglgakVtvlDvrpa 62
                 kv viG+G+ G+  +a   + g +Vtv++ +++
   EEA22436.1 10 KVAVIGAGISGVVTAAHLLNAGLEVTVFERNKE 42
                 8****************************9987 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 1.2
                  EEEEESTSHHHHH CS
  AlaDh_PNT_C  30 kvlviGgGvaGlq 42 
                  +vl iGgGv  + 
   EEA22436.1 233 NVLLIGGGVSSTD 245
                  6999*****8775 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   1.6   0.00016      0.12       1      31 [.      10      40 ..      10      47 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00016
                CEEEE-SSHHHHHHHHHHHHTT--EEEEES- CS
        GIDA  1 dviViGgGhAGceAAlaaarlGakvlLithk 31
                +v ViG+G +G+  A+++ ++G++v+ +  +
  EEA22436.1 10 KVAVIGAGISGVVTAAHLLNAGLEVTVFERN 40
                699**********************999655 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.0     0.013       9.5       1      37 [.      10      42 ..      10      53 .. 0.91
   2 ?    3.6   0.0      0.13        97      33      87 ..     292     347 ..     280     357 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.013
                   EEEEETTSHHHHHHHHHHHHTTS-GGCEEEEEESSCC CS
  F420_oxidored  1 kigiiGaGnmgealasgllaagaqpheivvansrnpe 37
                   k+++iGaG  g   a  ll+ag    e++v  +rn+e
     EEA22436.1 10 KVAVIGAGISGVVTAAHLLNAG---LEVTVF-ERNKE 42
                   79********************...9**977.99887 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.13
                    ESSCCCH.HHHHHHHC-EEECECHHHHHHH-SEEEE-S-HHHHHHHHHHCGHHHHT CS
  F420_oxidored  33 srnpeka.eelaeelgvkvtavdneeaaeeadvvvlavkpedveevlselakdalk 87 
                    +r++e + +e +  ++v ++++d+  ++e+ d ++++  ++ +  +l+ l +d+ k
     EEA22436.1 292 TRTEEPLtAESHLPIKVHLKSTDQDSTIEDIDYIIVCTGYYFTLPFLRRLHEDDTK 347
                    444444413444566788999999*******************9999999666554 PP

>> IlvN  Acetohydroxy acid isomeroreductase, NADPH-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.1   0.00051      0.38       6      37 ..      10      41 ..       7      48 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00051
                -EEEES-SHHHHHHHHHHHHTT--EEEEE-TT CS
        IlvN  6 kiaviGyGsqGhaqalnlrdsgldvvvglreg 37
                k+aviG G  G + a  l ++gl+v+v  r++
  EEA22436.1 10 KVAVIGAGISGVVTAAHLLNAGLEVTVFERNK 41
                8*************************987766 PP

>> NAD_Gly3P_dh_N  NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.1    0.0017       1.2       1      33 [.      10      42 ..      10      57 .. 0.94
   2 ?   -0.2   0.0       1.1   8.5e+02      33      90 ..     284     342 ..     233     366 .. 0.64

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.0017
                    -EEEE--SHHHHHHHHHHHTTT--EEEE-S-HH CS
  NAD_Gly3P_dh_N  1 kiavlGaGswGtalAkvlaenghevrlwvreee 33
                    k+av+GaG  G   A++l ++g ev+++ r++e
      EEA22436.1 10 KVAVIGAGISGVVTAAHLLNAGLEVTVFERNKE 42
                    79***************************9986 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 1.1
                     HHHHHHHHHSSBTTTBTT----TTEEE.ES-HHHHHTT--EEEE---HHHHHHHHHHHC CS
  NAD_Gly3P_dh_N  33 elieeineehenvkyLpgiklpenlva.ttdlaealkgadiivlvvPsqalrevlkklk 90 
                     e +e  +++++++    + +lp +++  +td ++++++ d+i++     ++  +l++l+
      EEA22436.1 284 EFFEITSATRTEEPLTAESHLPIKVHLkSTDQDSTIEDIDYIIVCTGYYFTLPFLRRLH 342
                     55555566666666677778888887525788999999999998887777766666665 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.0    0.0035       2.6       9      39 ..      10      40 ..       7      85 .. 0.82
   2 ?   -2.3   0.0       8.4   6.3e+03      29      68 ..     144     191 ..     138     196 .. 0.46
   3 ?    1.5   0.4      0.53     4e+02       6      23 ..     230     247 ..     228     332 .. 0.64

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.0035
  NAD_binding_7  9 kvlvvGgGevAarkvrklleagakvtvvape 39
                   kv v+G+G  +   + +ll+ag +vtv   +
     EEA22436.1 10 KVAVIGAGISGVVTAAHLLNAGLEVTVFERN 40
                   799************************9877 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 8.4
  NAD_binding_7  29 agakvtvvapevkeeleelvkla...eee....l..ekdlegadlviaa 68 
                    +gakvt + +  +e ++ +v+++   e++    +  +++ + +d v++a
     EEA22436.1 144 FGAKVTNIEKV-NELSKWQVSWTelrEDDetgeVneQEKNDLFDAVVVA 191
                    56777776665.5555555555321122211111212223335566655 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.53
  NAD_binding_7   6 kgkkvlvvGgGevAarkv 23 
                     gk+vl++GgG   +  +
     EEA22436.1 230 AGKNVLLIGGGVSSTDIA 247
                    578999999986555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (488 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       458  (0.0255452); expected 358.6 (0.02)
Passed bias filter:                      426  (0.0237604); expected 358.6 (0.02)
Passed Vit filter:                        64  (0.00356964); expected 17.9 (0.001)
Passed Fwd filter:                        24  (0.00133861); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              24  [number of targets reported over threshold]
# CPU time: 0.75u 0.33s 00:00:01.08 Elapsed: 00:00:00.53
# Mc/sec: 2749.17
//
Query:       EEA22437.1  [L=510]
Description: MFS transporter Liz1/Seo1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-35  122.3  23.2    7.3e-34  117.2  12.7    2.1  2  MFS_1     Major Facilitator Superfamily
    3.8e-07   29.7   1.0    3.8e-07   29.7   1.0    1.8  2  MFS_4     Uncharacterised MFS-type transporter YbfB


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.2  12.7   8.1e-38   7.3e-34       2     341 ..      59     418 ..      58     427 .. 0.80
   2 !   19.0   2.7   6.1e-08   0.00055      28     150 ..     313     446 ..     301     482 .. 0.70

  Alignments for each domain:
  == domain 1  score: 117.2 bits;  conditional E-value: 8.1e-38
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.sslw.lllvlrvlqGlg 98 
                 +l++f+ +l+  +++ a+ + ++edlg+ + +++ ++++ ++g++++++p     +++ +r ++ ++ +++++  +++l + +++   ++v+r++ Gl+
  EEA22437.1  59 SLGYFIKYLDQININNAFVSGMQEDLGLYGNQLNYMTAAWTVGYVLGQIPSNIALTKLPPRYWIPAAEVIWSVL-TMGL-SrANSArQIYVMRFFIGLA 155
                 689***********************************************************************.7887.5588899************ PP

       MFS_1  99 agalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg......Wravfyilaivsllafvlfllllpeepperkrkspkeee... 188
                 +++++p+++++i  w+ k+e ++   ++ ++++lG+++   l +++++++g      W+++f+i +++sl +++ ++++++ + pe +++   +e+   
  EEA22437.1 156 ESTFYPGMQYIIGSWYRKDELAKRSCIFHTSSGLGSMFSGYLMAAVYHLGGrggfkgWQWLFIIDGVISLPVAL-AGFFILPDVPEISNPWYLTEKeva 253
                 ***********************************************8888*********************88.566666666666666555554556 PP

       MFS_1 189 .........kgtgpaplvp..awkallkdpvlwillialllfffgfsg....lltllplylqevlglsglllaglllallalvgailallagrlsdr.l 271
                           +  ++p  +   +k++++  +++ +l++l++ f   +g    l ++l + ++  + ++  + a+     +++v ++  l+ ++ sd  +
  EEA22437.1 254 lakkrmeleGRGTRQPY-TkaKIKKIFSTWHIY-FLTVLYISFNNANGgqpvLAQWLKSSTNPKYTIP-QVNAY--ATTPYAVQVVTTLIYAWTSDTiF 347
                 77777666422222222.246788888888885.444444444444447999*******777777777.45555..66666666666999*****7756 PP

       MFS_1 272 grrrrlllallllllaalglallavtssavllllvlvliGfglgfvfpsllalasdlapp..eeagtasglf 341
                 + rr   + +++l+ +++g  lla+     + ++ ++  G g+g+ +++ +a+a + + +  ee++  +g +
  EEA22437.1 348 NGRRWPPILFGALSNIVCGASLLAWDIPRGWKWFCYIYSGAGYGL-SGLCMAWAHEICTKdnEERALTVGSM 418
                 667777777777777777777777776799999888888999998.79999999999966224444444444 PP

  == domain 2  score: 19.0 bits;  conditional E-value: 6.1e-08
       MFS_1  28 g..ispseigllltlyalgaavaslplGrlsdrf..Grrr.vlllglllfalg.lllllfasslwlllvlrvlqGlgagalfpagaaliadwfpkeerg 120
                 +  ++  +++  +t+ +++++v++l++++ sd +  Grr+  +l+g+l+ +++ + ll++ ++  + +++ + +G+g+ +l  +++a++ ++ +k++  
  EEA22437.1 313 NpkYTIPQVNAYATTPYAVQVVTTLIYAWTSDTIfnGRRWpPILFGALSNIVCgASLLAWDIPRGWKWFCYIYSGAGY-GLSGLCMAWAHEICTKDNEE 410
                 44477888899999999***************9669*****************6666666333235788888899997.77888899999999998888 PP

       MFS_1 121 raigllsagfslGailgpllggllasslg.......W 150
                 ra+  +++++ +++++ + l  ++ +++        W
  EEA22437.1 411 RAL-TVGSMNEMAYVFQAWLPLIVWQQVDapryhkgW 446
                 888.455557777766666655555555555555444 PP

>> MFS_4  Uncharacterised MFS-type transporter YbfB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.7   1.0   4.3e-11   3.8e-07      18     167 ..      79     229 ..      75     250 .. 0.85
   2 ?   -3.0   0.0      0.38   3.4e+03     316     359 ..     322     366 ..     313     372 .. 0.64

  Alignments for each domain:
  == domain 1  score: 29.7 bits;  conditional E-value: 4.3e-11
       MFS_4  18 allaegqlslsqagllaaaNylGYLvGallaafalsagaeRlrllagllatvllllamaltesfaaflliRflaGvasAvvlvfgsslvlahaaaarre 116
                  + ++++l  +q+ ++ aa  +GY +G +   +al + + R  + a+ +   +l++  + ++s   + ++Rf  G+a  +    +  ++ +   + + +
  EEA22437.1  79 GMQEDLGLYGNQLNYMTAAWTVGYVLGQIPSNIALTKLPPRYWIPAAEVIWSVLTMGLSRANSARQIYVMRFFIGLAESTFYPGMQYIIGSWYRKDELA 177
                 5889999999*******************************************************************9987777777776666666667 PP

       MFS_4 117 rvgallfaGvGlGiavsgllvllllqlglsassl.Wlalavlsavllllval 167
                 +   +++   GlG + sg l++++ +lg  + +  W++l ++  v+ l val
  EEA22437.1 178 KRSCIFHTSSGLGSMFSGYLMAAVYHLGGRGGFKgWQWLFIIDGVISLPVAL 229
                 777788899***********99999999887766677666666665555543 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.38
       MFS_4 316 lglmTasfgigQilGpllasllaea..tgslalallvaaaalvlaa 359
                  + +T+ +++ Q++  l+ ++ +++   g   +++l +a + ++++
  EEA22437.1 322 NAYATTPYAV-QVVTTLIYAWTSDTifNGRRWPPILFGALSNIVCG 366
                 5677777776.77777777777664214556666666666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (510 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       613  (0.0341904); expected 358.6 (0.02)
Passed bias filter:                      424  (0.0236488); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.46
# Mc/sec: 3349.98
//
Query:       EEA22438.1  [L=457]
Description: DNA-binding protein eta2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.2e-35  118.9  13.3    1.6e-13   50.6   0.3    3.3  3  Myb_DNA-binding  Myb-like DNA-binding domain
    1.5e-26   92.4   4.3    8.3e-10   38.8   1.3    3.3  3  Myb_DNA-bind_6   Myb-like DNA-binding domain
    1.2e-05   25.1   0.0       0.24   11.3   0.0    2.7  2  Myb_DNA-bind_7   Myb DNA-binding like
     0.0028   17.8   0.4       0.24   11.6   0.0    3.0  3  SANT_DAMP1_like  SANT/Myb-like domain of DAMP1
  ------ inclusion threshold ------
       0.14   12.5   0.4         19    5.6   0.0    2.9  3  HTH_Tnp_1        Transposase
       0.14   11.4   5.5       0.26   10.6   5.5    1.4  1  NOA36            NOA36 protein
       0.18   11.4   4.9       0.28   10.7   4.9    1.3  1  PPP4R2           PPP4R2
        3.1    5.8   6.3        4.3    5.3   6.3    1.1  1  DNA_pol_phi      DNA polymerase phi


Domain annotation for each model (and alignments):
>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.3   3.2     1e-12   2.3e-09       1      44 [.       5      53 ..       5      55 .. 0.90
   2 !   50.6   0.3     7e-17   1.6e-13       1      45 [.      61     105 ..      61     106 .. 0.96
   3 !   37.1   0.1   1.2e-12   2.7e-09       3      44 ..     114     156 ..     112     158 .. 0.92

  Alignments for each domain:
  == domain 1  score: 37.3 bits;  conditional E-value: 1e-12
                     CSSSBHHHHHHHHHHHHH.HTTC....HHHHHHHHTSS-HHHHHHHHHH CS
  Myb_DNA-binding  1 rgkWteeEdelLleavkk.hGnr....WkkIaerlggRtekqcrsrwrn 44
                     r +Wt+eEd  L ++v++   n+    W++ a++++gRt k+cr rw n
       EEA22438.1  5 RRNWTAEEDAHLRKLVNNeIENSrpllWRALAKKVPGRTNKDCRKRWWN 53
                     679*************99444668***********************98 PP

  == domain 2  score: 50.6 bits;  conditional E-value: 7e-17
                      CSSSBHHHHHHHHHHHHHHTTCHHHHHHHHTSS-HHHHHHHHHHH CS
  Myb_DNA-binding   1 rgkWteeEdelLleavkkhGnrWkkIaerlggRtekqcrsrwrny 45 
                      rg+W++ E ++L++av +hG +W+++a+ +g+R + qc s+w ++
       EEA22438.1  61 RGPWSQAENKRLIKAVSEHGTNWNEVAHIVGTRYADQCSSHWSQV 105
                      89****************************************876 PP

  == domain 3  score: 37.1 bits;  conditional E-value: 1.2e-12
                      SSBHHHHHHHHHHHHHHTTCHHHHHH.HHTSS-HHHHHHHHHH CS
  Myb_DNA-binding   3 kWteeEdelLleavkkhGnrWkkIae.rlggRtekqcrsrwrn 44 
                       Wt+eEde+Ll av  hG  W++Ia  + + Rt  + ++r++ 
       EEA22438.1 114 DWTAEEDEKLLHAVLSHGTTWSTIATsHTPKRTTLALKNRYYA 156
                      5***********************665999***********85 PP

>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.8   1.3   3.7e-13   8.3e-10       1      60 []       8      72 ..       8      72 .. 0.92
   2 !   33.7   0.2   1.4e-11   3.2e-08       1      47 [.      64     110 ..      64     113 .. 0.94
   3 !   31.0   0.0     1e-10   2.3e-07       1      44 [.     115     158 ..     115     177 .. 0.89

  Alignments for each domain:
  == domain 1  score: 38.8 bits;  conditional E-value: 3.7e-13
  Myb_DNA-bind_6  1 WteeEdeiLlklveky.gn....dWknIaealnrRtpkqcfdrwknkLrpkisrkkwskeedirL 60
                    Wt+eEd  L+klv +  +n     W+  a+  + Rt k+c+ rw n+L  +  r++ws++e +rL
      EEA22438.1  8 WTAEEDAHLRKLVNNEiENsrplLWRALAKKVPGRTNKDCRKRWWNSLANSTARGPWSQAENKRL 72
                    **************9756656777********55****************************997 PP

  == domain 2  score: 33.7 bits;  conditional E-value: 1.4e-11
  Myb_DNA-bind_6   1 WteeEdeiLlklvekygndWknIaealnrRtpkqcfdrwknkLrpki 47 
                     W+++E+++L+k v+++g +W+++a + + R + qc  +w ++L+ +i
      EEA22438.1  64 WSQAENKRLIKAVSEHGTNWNEVAHIVGTRYADQCSSHWSQVLDLDI 110
                     ***************************99***********9887666 PP

  == domain 3  score: 31.0 bits;  conditional E-value: 1e-10
  Myb_DNA-bind_6   1 WteeEdeiLlklvekygndWknIaeal.nrRtpkqcfdrwknkLr 44 
                     Wt+eEde+Ll  v  +g  W++Ia+   ++Rt +++++r+   Lr
      EEA22438.1 115 WTAEEDEKLLHAVLSHGTTWSTIATSHtPKRTTLALKNRYYA-LR 158
                     **************************9669**********98.53 PP

>> Myb_DNA-bind_7  Myb DNA-binding like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.8   0.0   0.00015      0.34       5      43 ..      58      96 ..      54     104 .. 0.85
   2 !   11.3   0.0   0.00011      0.24       8      49 ..     112     154 ..     108     167 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00015
  Myb_DNA-bind_7  5 rkktkkWskeetekFYkaLsqfGtDFsliaklfpkrtrr 43
                    ++ + +Ws++e+++  ka+s+ Gt+++ +a++   r  +
      EEA22438.1 58 STARGPWSQAENKRLIKAVSEHGTNWNEVAHIVGTRYAD 96
                    567889*********************999998877655 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00011
  Myb_DNA-bind_7   8 tkkWskeetekFYkaLsqfGtDFsliakl.fpkrtrrqlKlKF 49 
                     +++W+ ee ek  +a+   Gt +s+ia+   pkrt   lK+++
      EEA22438.1 112 HCDWTAEEDEKLLHAVLSHGTTWSTIATShTPKRTTLALKNRY 154
                     689***********************9874799********99 PP

>> SANT_DAMP1_like  SANT/Myb-like domain of DAMP1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0      0.38   8.5e+02      27      42 ..       6      21 ..       2      23 .. 0.87
   2 ?    1.6   0.0      0.14   3.2e+02      27      50 ..      62      85 ..      46      97 .. 0.77
   3 !   11.6   0.0   0.00011      0.24      24      75 ..     110     157 ..      93     160 .. 0.85

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.38
  SANT_DAMP1_like 27 edWtkeetdyLfdlck 42
                     ++Wt ee  +L +l++
       EEA22438.1  6 RNWTAEEDAHLRKLVN 21
                     68*********99986 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.14
  SANT_DAMP1_like 27 edWtkeetdyLfdlckeydlrfvv 50
                       W++ e + L++ ++e  + +  
       EEA22438.1 62 GPWSQAENKRLIKAVSEHGTNWNE 85
                     34**************99999965 PP

  == domain 3  score: 11.6 bits;  conditional E-value: 0.00011
  SANT_DAMP1_like  24 lkeedWtkeetdyLfdlckeydlrfvviaDryelekkkkrsledlkeryYsv 75 
                      +++ dWt ee ++L++ + +  + +  ia  +      kr+   lk+ryY+ 
       EEA22438.1 110 INHCDWTAEEDEKLLHAVLSHGTTWSTIATSHT----PKRTTLALKNRYYAL 157
                      45678***********************98874....589999*******75 PP

>> HTH_Tnp_1  Transposase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.1       5.2   1.2e+04       4      11 ..       5      12 ..       3      18 .. 0.81
   2 ?    5.6   0.0    0.0087        19       4      31 ..      61      88 ..      59      95 .. 0.89
   3 ?    3.8   0.0     0.032        72       6      33 ..     114     141 ..     112     150 .. 0.91

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 5.2
   HTH_Tnp_1  4 rrrwsdef 11
                rr w++e+
  EEA22438.1  5 RRNWTAEE 12
                89999996 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0087
   HTH_Tnp_1  4 rrrwsdefKariVreslepgksvsevAr 31
                r  ws+++ +r+++ + e g++  evA 
  EEA22438.1 61 RGPWSQAENKRLIKAVSEHGTNWNEVAH 88
                567***********************96 PP

  == domain 3  score: 3.8 bits;  conditional E-value: 0.032
   HTH_Tnp_1   6 rwsdefKariVreslepgksvsevArrh 33 
                  w++e+ +++++ +l+ g++ s +A +h
  EEA22438.1 114 DWTAEEDEKLLHAVLSHGTTWSTIATSH 141
                 5************************998 PP

>> NOA36  NOA36 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   5.5   0.00011      0.26     258     304 ..     182     228 ..     137     233 .. 0.50

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00011
       NOA36 258 aylkalasgddeddegdedddddddeedddeeeddedeeeeeeeese 304
                 +  + + s++ +dd+++ + d +d+e d++ +ed+e+ ee++ +e+e
  EEA22438.1 182 KVASRIKSKNGQDDRSNGNGDTEDEEGDEEVDEDGEHREEDDGNEEE 228
                 23333444455556555555555555666655555555555444443 PP

>> PPP4R2  PPP4R2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   4.9   0.00012      0.28     149     279 ..      68     225 ..      36     231 .. 0.63

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00012
      PPP4R2 149 sseniingvlseelnse.......keedkansssqedsedvslvsipwvdekteselspfikeidsimsvnlgfedeeekeedd.........nesees 231
                 +++ +i+ v++ + n +          ++++ss+ ++  d     ++w+ e++e+ l ++    ++++++ ++ + ++ +   +         +++  +
  EEA22438.1  68 ENKRLIKAVSEHGTNWNevahivgTRYADQCSSHWSQVLDLDINHCDWTAEEDEKLLHAVLSHGTTWSTIATSHTPKRTTLALKnryyalrlrHQNAGN 166
                 445555555555555556677777788899999999999999999999999999999999999998888888777777766655789999987333444 PP

      PPP4R2 232 aseseeiteekdesvkvee...........kdddeeddeedtdyveeeeddesedddee 279
                 ++e  ++ + +++s+kv             ++ + ++++e+ d + +e+++  e+dd +
  EEA22438.1 167 HKEPVSAKAPSSPSIKVASrikskngqddrSNGNGDTEDEEGDEEVDEDGEHREEDDGN 225
                 44444555555666666665554344333333333333333333333333333333333 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   6.3    0.0019       4.3     645     681 ..     193     229 ..     182     262 .. 0.61

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0019
  DNA_pol_phi 645 eeddeeeeeeddeededseedddeeesdedeededde 681
                  ++d ++ +++ ++e+ d+e d+d e  +ed+ +e++e
   EEA22438.1 193 QDDRSNGNGDTEDEEGDEEVDEDGEHREEDDGNEEEE 229
                  3333444444444444444444433333333332222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (457 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       699  (0.0389871); expected 358.6 (0.02)
Passed bias filter:                      462  (0.0257683); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.57u 0.31s 00:00:00.87 Elapsed: 00:00:00.46
# Mc/sec: 3011.18
//
Query:       EEA22439.1  [L=505]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      1e-16   60.7   0.0    1.5e-14   53.5   0.0    2.4  2  Transferase  Transferase family


Domain annotation for each model (and alignments):
>> Transferase  Transferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.8   0.0   0.00052       9.4      17      80 ..       5      68 ..       3      72 .. 0.82
   2 !   53.5   0.0   8.6e-19   1.5e-14     208     433 ..     246     495 ..     136     496 .. 0.76

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.00052
  Transferase 17 tpeqtLkLSilDlllpevivk.acyfykknkelsqenvsekLktsLsetLtkfypLAGrLktses 80
                 +pe++++L  +D+  p  +++ a+y+   + + + e + + L ++L +t +  + L+G+++ ++s
   EEA22439.1  5 SPEVRIPLTPFDHCVPRAYYNgAIYLSIRPGVTFTE-AFAVLHEALHRTFVTVPWLSGKVHLQSS 68
                 678999******888877666267777777777777.69********************987775 PP

  == domain 2  score: 53.5 bits;  conditional E-value: 8.6e-19
  Transferase 208 kfsasettevkevvtkkivleklsaskleeLkkkasdesngkpa.trfesvtallWrcavkarkldeske...........tvlgiavdiRsrlepkl 293
                  + +++++t   ++++k  +++  s+s+l  L+   ++e  g    ++ ++v+al+Wrc+ +ar   ++             +vl ++ d R   +  l
   EEA22439.1 246 HAPPPKSTLRAQQLLKAGIFY-VSPSGLSALQRDIAQELGGSGGiSSNDAVCALIWRCFLRARSMARKASgnsseesgeadAVLNMVCDGRPNFSTGL 342
                  355666666777788888888.9***********99999998777**************9999887777777888999******************** PP

  Transferase 294 peeyfGNallsvvvkstakellseelsr..ivekvkeavkkaitkeylsseidweens....tlkaelvskgkkdg.eevtvsswlklplyevdFG.. 382
                  p++y GN++++v  k     l s + s   ++  + +    +i   +l+      +n     +l++ +  + ++ + +++ +ss   +p+ +v+FG  
   EEA22439.1 343 PPKYLGNITFNVLSKLPLPSLTSTDTSIatVAATIRRGAS-SIGSAHLMDLYTLLQNLsgfdDLARWKRNRTSSIEgNNMAISSMIMFPVSDVNFGdr 439
                  ***************9999999887664104444444444.4777777777776666678887877777777666669******************66 PP

  Transferase 383 .wgkPvyvvpvvsskkdnk.....illlpskeddggvevlvtLpeeemskfeeeael 433
                    g+  +v   ++  ++        ++lp + ++g+ve ++ L  eem  + e+ e+
   EEA22439.1 440 iFGNRGMVEAIRPFMDGLNrftriCFVLPRN-KNGSVEFVANLFDEEMDILMEDEEF 495
                  5566655555544333322445548999988.*****************99999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (505 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       333  (0.0185733); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 3261.21
//
Query:       EEA22440.1  [L=350]
Description: NAD dependent epimerase/dehydratase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.1e-23   82.7   0.0    2.8e-23   82.3   0.0    1.1  1  3Beta_HSD        3-beta hydroxysteroid dehydrogenase/isomeras
    8.1e-21   74.6   0.0    1.1e-20   74.1   0.0    1.2  1  Epimerase        NAD dependent epimerase/dehydratase family
    3.7e-12   46.3   0.0    2.2e-11   43.8   0.0    1.9  2  GDP_Man_Dehyd    GDP-mannose 4,6 dehydratase
    1.4e-11   44.6   0.0    3.6e-11   43.3   0.0    1.6  1  NAD_binding_10   NAD(P)H-binding
    3.3e-10   39.6   0.0    4.3e-10   39.2   0.0    1.2  1  NAD_binding_4    Male sterility protein
    5.4e-08   32.7   0.0    9.9e-08   31.8   0.0    1.4  1  NmrA             NmrA-like family
     0.0008   18.9   0.0     0.0016   17.9   0.0    1.5  1  adh_short        short chain dehydrogenase
     0.0017   17.6   0.0     0.0031   16.7   0.0    1.4  1  Polysacc_synt_2  Polysaccharide biosynthesis protein
  ------ inclusion threshold ------
      0.064   13.2   0.1       0.15   11.9   0.1    1.6  1  KR               KR domain


Domain annotation for each model (and alignments):
>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.3   0.0   1.4e-26   2.8e-23       1     229 [.      10     243 ..      10     253 .. 0.86

  Alignments for each domain:
  == domain 1  score: 82.3 bits;  conditional E-value: 1.4e-26
   3Beta_HSD   1 vvtGgaGFlGralvkeLvrleelkevrvlDlrespelleelskvnvkk.......viegDvtdkdkleealegvdvvihlaslvdvagkltedeimkvn 92 
                 +vtGg+GFlG++ + +L++++ l    +  l + +++ e+l++ + ++       ++e+D+++ +  ++a+eg    +h+as ++v+    ++e+    
  EEA22440.1  10 LVTGGSGFLGAYCIIALLKEGYLVRTSIRSLSKASKVTESLKNAGLTDvdlnrlsIVEADLNKDQGWDKAVEGCTYALHVASPIPVTIPKDDNELIVPA 108
                 69*******************97777777788888888899988887777888889********************************88888888888 PP

   3Beta_HSD  93 vkGTrnvleacvkagvrvlvYtSsaevvgpnslgeeilngdEeleyeslhqdaypesKalaEklvlkaNgrtlkngg.rlyTcaLRpagiyGegdkllv 190
                  +GT  vl a+++agv+++v tSs ++vg  +  ++    +E++  e++   ayp+sK  aE++         k+ g  l   a+ p++++G+   + +
  EEA22440.1 109 REGTLRVLRAAKRAGVKRVVLTSSFNAVGYGHPDQAKPFTEESWSNEKSKLGAYPQSKVAAERAAWDFVK---KGDGkGLELTAINPVAMFGPVLGTEM 204
                 9***************************986655555556**********************87544333...3333479999**********999999 PP

   3Beta_HSD 191 pllkqlaklglalfkigdeevlsdrvYvgNvawahilAa 229
                 p+  ++++  ++    ++ +  +  v v  va  h+lA+
  EEA22440.1 205 PSSIHIIQRYMTGEMPASLNLYMGVVDVRDVAVLHLLAM 243
                 998888888877777788888899999999999999997 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.1   0.0   5.6e-24   1.1e-20       1     233 [.       9     250 ..       9     256 .. 0.82

  Alignments for each domain:
  == domain 1  score: 74.1 bits;  conditional E-value: 5.6e-24
                 EEEETTTSHHHHHHHHHHHHCTSEEEEEES-.STTTTCHHCHHC.............EEEE--TT-HHHHHHHHHHHT-SEEEE--S---HHHHHHSHH CS
   Epimerase   1 ilVtGatGfiGsalvkallekgyevigldrl.ssasntarledl.............elveldltdrsalerlfkeeqpdavihlAavggvaassedpa 85 
                 +lVtG++Gf+G++ + all++gy v +  r  s+as+  +   l             ++ve+dl +++ ++++++  ++++ +h+A    + +  +d +
  EEA22440.1   9 VLVTGGSGFLGAYCIIALLKEGYLVRTSIRSlSKASKVTES--LknagltdvdlnrlSIVEADLNKDQGWDKAVE--GCTYALHVAS-PIPVTIPKDDN 102
                 79********************9966555540444433332..245899**************************..********65.33333357889 PP

                 HHHHHHTHHHHHHHHHHHHHTCTEEEEEEEGGGGTSCSS...SSBSTCSTTS----SSHHHHHHHHHHHHHHHHHHHH.T..-EEEEEEESEEESTTS- CS
   Epimerase  86 dfieknlqgtlnlleaarkagvkrllflsSsevYGkdae...qpkeettltgplkpnspYaaaKlageklveayaaqy.g..lnaiilrlfnlyGprng 178
                 ++i    +gtl++l aa++agvkr++  sS    G +++   +p +e++ + +     +Y  +K+a+e+ ++++ +++ g  l+ +++++  ++Gp  g
  EEA22440.1 103 ELIVPAREGTLRVLRAAKRAGVKRVVLTSSFNAVGYGHPdqaKPFTEESWSNEKSKLGAYPQSKVAAERAAWDFVKKGdGkgLELTAINPVAMFGPVLG 201
                 99999*************************7776655554345877777788889********************9985255***************55 PP

                 TTSTTSHHHHHHHHHHTTSSSEEEETTST-EEEEEEHHHHHHHHHHHHHHHTT-S CS
   Epimerase 179 egevsrvipalirkilegkqevtllgdgtalRdflyveDvaeaillvlehvdagd 233
                 ++ +s++  ++i++  +g+    +  +++  +  ++v+Dva ++ll+++ ++a+ 
  EEA22440.1 202 TEMPSSI--HIIQRYMTGE----MPASLNLYMGVVDVRDVAVLHLLAMTSPAAKG 250
                 5555555..6899999999....8888899999*****************98864 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.8   0.0   1.1e-14   2.2e-11       1     169 [.      10     178 ..      10     231 .. 0.78
   2 ?    0.3   0.0      0.19   3.8e+02     305     329 ..     311     335 ..     298     337 .. 0.77

  Alignments for each domain:
  == domain 1  score: 43.8 bits;  conditional E-value: 1.1e-14
                    EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-..TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHHHHT-SEEEE--S---HHHHTTS CS
  GDP_Man_Dehyd   1 LiTGiaGfiGsylaelLlekgyevhgivrrsssf..ntgriehlakdpkeeleenlklhkgDltDssslerllaevqpdevynLAAqshVdvsfek 94 
                    L+TG++Gf G+y +  Ll++gy v   +r  s+    t+++++     +++  ++l+++++Dl+  +  +++++ +  +  ++ A    V    ++
     EEA22440.1  10 LVTGGSGFLGAYCIIALLKEGYLVRTSIRSLSKAskVTESLKNAG-LTDVD-LNRLSIVEADLNKDQGWDKAVEGC--TYALHVASPIPVTIPKDD 101
                    9***********************998885554311455555543.23333.369********************9..566999999999999999 PP

                    HHHHHHHHTHHHHHHHHHHHHCT..TTSEEEEEEE..GGGG-S-.SSSSB-TTS-----S...HHHHHHHHHHHHHHHHHH CS
  GDP_Man_Dehyd  95 PeytaevnvlGtlrLLeairalglekkvrfyqaSt..sEvYGkv.qevpqtEttpfyPrs...PYaaaKlyadwivvnyre 169
                     e  + +   Gtlr+L a++++g++   r++ +S+  +  YG++ q+ p+tE+   + +s    Y  +K++a+  + ++ +
     EEA22440.1 102 NELIVPA-REGTLRVLRAAKRAGVK---RVVLTSSfnAVGYGHPdQAKPFTEESWSNEKSklgAYPQSKVAAERAAWDFVK 178
                    8888777.89*************95...777777732445***945789***98887776444799999999987766655 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.19
                    B--B-THHHHHHH----SS-HHHHH CS
  GDP_Man_Dehyd 305 lllgdaskakeeLgWkpkvsfeelv 329
                    + +  ++ka + LgW+p+ + +++v
     EEA22440.1 311 RKASSNEKAVNILGWTPRSREDTIV 335
                    5567889**********97766655 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.3   0.0   1.8e-14   3.6e-11       1     145 [.      13     194 ..      13     203 .. 0.69

  Alignments for each domain:
  == domain 1  score: 43.3 bits;  conditional E-value: 1.8e-14
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCH.......HHHCTT........TCEEEE--TT-CCHHHHHHTT-S.EEEES-.....--TCC. CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpekla.......eleaee........glevvegdvtdvedlaealkgad.aVvsal.....ggggk. 73 
                     G++G  G + +  ll++g + v+  +R+ +k++       +    +        +l++ve+d+++ +   +a++g+  a  +a         ++ 
      EEA22440.1  13 GGSGFLGAYCIIALLKEG-YLVRTSIRSLSKASkvteslkN----AgltdvdlnRLSIVEADLNKDQGWDKAVEGCTyALHVASpipvtI-PKDd 101
                     99***************5.*********9999833343330....233333343899*******************96666666667742.3332 PP

                     ......HHHHHHHHHHHHHHCT--EEEEEEETTT.TSGCGCHHHH.....HHHH..CCHHH....HHHHHHHHHHHHH...SSSEEEEEEE-C CS
  NAD_binding_10  74 ......deegaknivdaakeagvkRfvlvsaigv.gdevpgefge.....wnke..llkay....laakraaeellra...sgldwTivrpgg 145
                            +eg+ ++++aak+agvkR+vl s++++ g  +p++ ++     w +e   l+ay    +aa raa + +++   +gl+ T + p +
      EEA22440.1 102 nelivpAREGTLRVLRAAKRAGVKRVVLTSSFNAvGYGHPDQAKPfteesWSNEksKLGAYpqskVAAERAAWDFVKKgdgKGLELTAINPVA 194
                     3455555555*********************98743334444333111115543346677722224556666666776888899999998876 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.2   0.0   2.2e-13   4.3e-10       1     190 [.      11     176 ..      11     230 .. 0.83

  Alignments for each domain:
  == domain 1  score: 39.2 bits;  conditional E-value: 2.2e-13
                    EE-TTSHHHHHHHHHHHHHS-.TEEEEEE-SSSHHHHHHHHHHHT-SS-HHHHHHHHHTTTEEEEE--TTSGGGG--HHHHHHHHHH--EEEE--S CS
  NAD_binding_4   1 lTGaTGFLGkvLlekLLrttpevkiyllvRaksgesaeeRleeelekkelfsallkelaerikvveGDlseprlGLseedlqelaeevdviihsaA 96 
                    +TG++GFLG++ +  LL++     +   +R+    s + +++e+l++ +l ++     ++r+++ve+Dl++++       +++ +e ++  +h+a 
     EEA22440.1  11 VTGGSGFLGAYCIIALLKEGY--LVRTSIRSL---SKASKVTESLKNAGLTDVD----LNRLSIVEADLNKDQ------GWDKAVEGCTYALHVAS 91 
                    7******************87..444444444...5589999*********999....6***********976......89*************** PP

                    S-S.STTSSE..EHHHHHHHHHHHHHHHTSSS--.-EEEEEE..GGGTTS-TTT--SSS-H......HHH--EEEETTTCCCHHHHHHHHHHHHHH CS
  NAD_binding_4  97 tvnfdepyke..llrvNveGtrevlelakklkklkvllhvST..ayvngeregeveekvyeegekeekldederaklkglpntYeqsKalaEklvr 188
                     + ++ p ++  l+ +  eGt +vl+ ak+   +  ++  S+  a+ +g+  ++   k            e++ +++k+   +Y qsK++aE+   
     EEA22440.1  92 PIPVTIPKDDneLIVPAREGTLRVLRAAKRAGVK-RVVLTSSfnAVGYGHPDQA---K---------PFTEESWSNEKSKLGAYPQSKVAAERAAW 174
                    9776665544349****************88888.8888888776666666632...3.........4567777777888899*********9766 PP

                    HH CS
  NAD_binding_4 189 ea 190
                    + 
     EEA22440.1 175 DF 176
                    54 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.8   0.0     5e-11   9.9e-08       1     106 [.       9     136 ..       9     150 .. 0.80

  Alignments for each domain:
  == domain 1  score: 31.8 bits;  conditional E-value: 5e-11
                 EEESSTTSHHHHHHHHHHHHHT-EEEEEES-S..-SHHHHHHHHSTTE........EEES-TT-HHHHHHHHTT-SEEEE---GG...........S-H CS
        NmrA   1 IlviGaTGrqGksvvrallkaghkvralvRdt..kselakslkeaGve........lvkgdlddkeslvealkgvdvvfsvtgfy...........ske 78 
                 +lv+G++G +G++ + allk+g+ vr  +R +   s++ +slk+aG +        +v++dl+ ++  ++a++g   +  v +                
  EEA22440.1   9 VLVTGGSGFLGAYCIIALLKEGYLVRTSIRSLskASKVTESLKNAGLTdvdlnrlsIVEADLNKDQGWDKAVEGCTYALHVASPIpvtipkddnelIVP 107
                 79*****************************98877888999999975444444448899999***********9998888776677799985433222 PP

                 HHHHH.HHHHHHHHHS-SEEEEEE---GG CS
        NmrA  79 iedgk.klvdAakeaGvkhfiySslgddn 106
                  ++g+ ++ +Aak+aGvk+++  s ++++
  EEA22440.1 108 AREGTlRVLRAAKRAGVKRVVLTSSFNAV 136
                 356652688***********998877766 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.0   7.9e-07    0.0016       2      71 ..       8      83 ..       7      89 .. 0.88

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 7.9e-07
                EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT......TSEEEEEE-TTTSHHHHHHHHHHH CS
   adh_short  2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee......gakalaiqvDvtdreevealveka 71
                 vlvtG+s+ +G  +  +l+keG+ v    rs +k+ +v ++lk++       +++ ++++D+++ + ++++ve +
  EEA22440.1  8 NVLVTGGSGFLGAYCIIALLKEGYLVRTSIRSLSKASKVTESLKNAgltdvdLNRLSIVEADLNKDQGWDKAVEGC 83
                69*******************************************9765443356899999999999999999876 PP

>> Polysacc_synt_2  Polysaccharide biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   1.5e-06    0.0031       1     132 [.       9     136 ..       9     139 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 1.5e-06
                      EEEETTTSHHHHHHHHHHHHH...B-SEEEEEES-HHHHHHHHHH......-TTEEEE....E--TT-HHHHHHHTT..T-SEEEE------HH CS
  Polysacc_synt_2   1 vlvtGagGsiGselvrqilkk...kpkkiillerdElklyeiekeleeelkkkklkveivpvigdvrdkerlekaleelkvdvvfhaAAlKhVP 91 
                      vlvtG++G +G   +  +lk+     ++i+ l+++ +   ++++   ++++ ++l+     v +d+++ +  +ka+e  ++ + +h+A    V 
       EEA22440.1   9 VLVTGGSGFLGAYCIIALLKEgylVRTSIRSLSKASKVTESLKNAGLTDVDLNRLS----IVEADLNKDQGWDKAVE--GCTYALHVASPIPVT 96 
                      89************999999954344566667777777777777655555555553....4479*************..*********987776 PP

                      HHHHSHHHHHHHHHHHHHHHHHHHHHTT-SEEEEEEEGGGS CS
  Polysacc_synt_2  92 lveenpleaiktNvlgtenvieaaieagvkkvvliStDKAv 132
                      +  +   e i     gt  v++aa++agvk+vvl S+  Av
       EEA22440.1  97 IP-KDDNELIVPAREGTLRVLRAAKRAGVKRVVLTSSFNAV 136
                      55.55678888999**********************97776 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.1   7.8e-05      0.15       3      86 ..       9      84 ..       7     146 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 7.8e-05
                EEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-......EEEE----TT-HHHHHHHHHHHHHHSS---EEE CS
          KR  3 ylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealga......evevvaaDvsdkdavealleeikaeeppikGvi 86
                +l+tGG G LG   +  l+++g   lv +s +  + +++++ +++l++ g       + ++v+aD+ + +   +++          +G+ 
  EEA22440.1  9 VLVTGGSGFLGAYCIIALLKEG--YLVRTSIR--SLSKASKVTESLKNAGLtdvdlnRLSIVEADLNKDQGWDKAV----------EGCT 84
                79*******************9..57888877..344444577777777653333334445555555544444444..........4444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (350 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       315  (0.0175693); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 2481.08
//
Query:       EEA22441.1  [L=261]
Description: oxidoreductase, short-chain dehydrogenase/reductase family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-40  138.6   0.0    2.1e-40  138.3   0.0    1.1  1  adh_short        short chain dehydrogenase
    2.3e-25   89.6   0.0      3e-25   89.1   0.0    1.1  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    1.5e-08   34.7   0.0    2.3e-08   34.2   0.0    1.2  1  KR               KR domain
    6.8e-05   22.8   0.0    0.00016   21.6   0.0    1.6  2  NAD_binding_10   NAD(P)H-binding
    0.00062   19.3   0.0     0.0012   18.3   0.0    1.5  2  Epimerase        NAD dependent epimerase/dehydratase family
     0.0019   18.5   0.0     0.0035   17.6   0.0    1.4  1  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma
  ------ inclusion threshold ------
       0.01   16.0   0.0      0.022   14.9   0.0    1.5  1  NAD_binding_2    NAD binding domain of 6-phosphogluconate deh
      0.017   14.7   0.0       0.03   14.0   0.0    1.4  1  ApbA             Ketopantoate reductase PanE/ApbA
       0.03   14.9   0.1      0.076   13.6   0.1    1.6  1  F420_oxidored    NADP oxidoreductase coenzyme F420-dependent
      0.035   13.2   0.0      0.045   12.9   0.0    1.1  1  RmlD_sub_bind    RmlD substrate binding domain
      0.061   13.4   0.0       0.12   12.5   0.0    1.4  1  Shikimate_DH     Shikimate / quinate 5-dehydrogenase
       0.18   11.1   0.0       0.37   10.1   0.0    1.4  1  THF_DHG_CYH_C    Tetrahydrofolate dehydrogenase/cyclohydrolas
       0.19   11.0   0.1       0.28   10.5   0.1    1.2  1  DUF1776          Fungal family of unknown function (DUF1776)


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.3   0.0   1.5e-43   2.1e-40       2     187 ..       7     194 ..       6     200 .. 0.95

  Alignments for each domain:
  == domain 1  score: 138.3 bits;  conditional E-value: 1.5e-43
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---S...S--SSGGGCS CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGi...tgsgpfsels 97 
                 + lv+Ga++GIG+a++ +l+k+Gakv+vv+r++e+l e +   +e  +++  +q+D+++ +++ ++v++ +k+   +d ++ NAGi      ++ ++++
  EEA22441.1   7 HFLVIGATAGIGQALSSRLIKSGAKVTVVGRRKERLDEFVRVNGE--QSVRGLQFDISNLDDIPEFVAQTMKQPTDIDSIIFNAGIqtpMDLADPEKFD 103
                 569************************************999887..58*************************************8777778888999 PP

                 HHHHHHHHHHHTHHHHHHHHHHHHHHH.HCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHH CS
   adh_short  98 eeewervievNltgvflltravlpaml.kqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdma 187
                  +++ + ++vN+ + + l++a+lp++l + s  + ++++S+ + vp a ++aYsAsKaa++ +t +l+++l+ ++i+v  + P++v+T++ 
  EEA22441.1 104 LTRFHEEMKVNFSSFVALAHAFLPYLLqNPSPTSFIFTGSNLAIVPAATLPAYSASKAALNVFTLCLREQLRHSNIKVLEISPPPVQTELH 194
                 999**********************99778889*******************************************************986 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.1   0.0   2.2e-28     3e-25       1     181 [.      12     196 ..      12     206 .. 0.90

  Alignments for each domain:
  == domain 1  score: 89.1 bits;  conditional E-value: 2.2e-28
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSE.E..EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EG.CSS-GGGH-HH CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneeakkrveelaeelgae.v..lecDVtdeeqvealveevvekfgklDilvnnagiapk.lkgpfletsre 93 
                   Ga  gIG+a+  +l + Ga+v ++ +++e+   ++e+++  g++ v  l+ D+++ +++ ++v++++++   +D ++ nagi ++   ++ ++++  
    EEA22441.1  12 GATAGIGQALSSRLIKSGAKVTVVGRRKER---LDEFVRVNGEQsVrgLQFDISNLDDIPEFVAQTMKQPTDIDSIIFNAGIQTPmDLADPEKFDLT 105
                   899*********************999998...555555555554556*************************************755556889*** PP

                   HHHHHHHHHTHHHHHHHHHHHH.HCTSC..CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGG CS
  adh_short_C2  94 efdraldvnlyslfllakaalp.lmkeg..gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasg 181
                    f++ ++vn+ s+++la+a+lp l+++    s + + s  a +  +   ay+a+Kaal+ +t +l  +l + +i+v  +sp p++T++ + 
    EEA22441.1 106 RFHEEMKVNFSSFVALAHAFLPyLLQNPspTSFIFTGSNLAIVPAATLPAYSASKAALNVFTLCLREQLRHSNIKVLEISPPPVQTELHDY 196
                   **********************655554799**********99999999*************************************98765 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.2   0.0   1.7e-11   2.3e-08       3     166 ..       8     173 ..       7     184 .. 0.82

  Alignments for each domain:
  == domain 1  score: 34.2 bits;  conditional E-value: 1.7e-11
                 EEEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TT... CS
          KR   3 ylitGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklle... 98 
                 +l++G++ g+G++l+  l+++ga+ + +++R+   +e+ +++++     + +v+ ++ D+s+ d++ + +++  ++   i  +i  Ag+     l+   
  EEA22441.1   8 FLVIGATAGIGQALSSRLIKSGAK-VTVVGRR---KERLDEFVRVN--GEQSVRGLQFDISNLDDIPEFVAQTMKQPTDIDSIIFNAGIQTPMDLAdpe 100
                 69********************96.7788999...23333455532..35689************************************9988776111 PP

                 T--HHHHHHHHTTTTHHHHHHHHHTTT.....S--SEEEEEEEHHHHH--TT-HHHHHHHHHHHHHHHHHHHH CS
          KR  99 emtaedleqvlapKvkGawnLhelled.....esldffvlfSSiagllgsagqanYaaaNaflDalaeyrrsq 166
                 + +  ++++ ++  ++    L +++ +      s   f+++ S  +++ +a+  +Y+a  a l+ +    r+q
  EEA22441.1 101 KFDLTRFHEEMKVNFSSFVALAHAFLPyllqnPSPTSFIFTGSNLAIVPAATLPAYSASKAALNVFTLCLREQ 173
                 56677888889999999999999887766654667899********************999999887665554 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.6   0.0   1.1e-07   0.00016       1      69 [.      12      89 ..      12     108 .. 0.79
   2 ?   -2.4   0.0       2.7   3.7e+03      47      77 ..     210     241 ..     207     256 .. 0.69

  Alignments for each domain:
  == domain 1  score: 21.6 bits;  conditional E-value: 1.1e-07
                    TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHH...CTTTCEEEE--TT-CCHHHHHHT.......T-SEEEES-- CS
  NAD_binding_10  1 GAtGkvGrllvkellargghevtalvRnpeklaele...aeeglevvegdvtdvedlaealk.......gadaVvsalg 69
                    GAt ++G++l ++l+++g  +vt++ R++e+l+e+     e+ ++ ++ d+++ +d+ e ++       ++d +++++g
      EEA22441.1 12 GATAGIGQALSSRLIKSG-AKVTVVGRRKERLDEFVrvnGEQSVRGLQFDISNLDDIPEFVAqtmkqptDIDSIIFNAG 89
                    9****************5.**************8763335567777788999988877766644446666677777666 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 2.7
                     -TT-CCHHHHHHTT-S.EEEES---TCCHHHH CS
  NAD_binding_10  47 dvtdvedlaealkgad.aVvsalggggkdeeg 77 
                     dv ++++ +   +g d +V+ ++g++++ +++
      EEA22441.1 210 DVFTEQAYKGLAEGKDqIVIGSIGPSETFNDI 241
                     77778888888889985677777877774444 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   8.9e-07    0.0012       2      63 ..       9      74 ..       8     120 .. 0.76
   2 ?   -2.5   0.0         2   2.8e+03     135     153 ..     149     167 ..     131     180 .. 0.73

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 8.9e-07
                EEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC.........EEEE--TT-HHHHHHHHHHH CS
   Epimerase  2 lVtGatGfiGsalvkallekgyevigldrlssasntarledl.........elveldltdrsalerlfkee 63
                lV+Gat  iG+al  +l + g +v+++ r++++  +               +  + d+ + +++ ++++++
  EEA22441.1  9 LVIGATAGIGQALSSRLIKSGAKVTVVGRRKERLDE-----FvrvngeqsvRGLQFDISNLDDIPEFVAQT 74
                8*****************************444333.....234466899988999999999888887765 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 2
                 ----SSHHHHHHHHHHHHH CS
   Epimerase 135 plkpnspYaaaKlageklv 153
                 p ++  +Y+a+K+a    +
  EEA22441.1 149 PAATLPAYSASKAALNVFT 167
                 4567778999998876555 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   2.5e-06    0.0035       2      68 ..       9      72 ..       8      83 .. 0.90

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 2.5e-06
                     EEE--.SHHHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHHHT CS
  Sacchrp_dh_NADP  2 liiGa.GsvGqavaellarhfdvdaeitvadrskeklealaakalgvrfeaialdaenyeavLaallk 68
                     l+iGa  ++Gqa+   l +++    ++tv++r ke+l++ +    ++++   ++d++n ++ + + ++
       EEA22441.1  9 LVIGAtAGIGQALSSRLIKSGA---KVTVVGRRKERLDEFVRVNGEQSVRGLQFDISNLDD-IPEFVA 72
                     89******************97...6****************99**************999.665555 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   0.0   1.6e-05     0.022       8      74 ..      15      86 ..       8      97 .. 0.70

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.6e-05
                   SHHHHHHHHHHHHTT-EEEEE-SSHHHHHHHHHTT...........EEE-SSHHHHHHHC.SEEEE-SSSHHHHHHHHH CS
  NAD_binding_2  8 GvMGsnmalnllkagykvavynrtkekveelvaeg...........akaaesieelvasl.dvvitmvkagkavdevie 74
                   + +G+ + ++l+k+g kv+v+ r+ke+++e+v  +           ++ +++       + ++v   +k+ +++d++i+
     EEA22441.1 15 AGIGQALSSRLIKSGAKVTVVGRRKERLDEFVRVNgeqsvrglqfdISNLDD-------IpEFVAQTMKQPTDIDSIIF 86
                   669*****************************87655563333333333333.......25666666666666666655 PP

>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   2.2e-05      0.03       2      40 ..       9      50 ..       8      86 .. 0.75

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 2.2e-05
                EEES-SH.HHHHHHHHHHHHTHCEEEE-SCH.HHHH.HHHHC CS
        ApbA  2 ailGaGa.iGsllaakLakagadvtlilrsr.rlea.lkknG 40
                +++Ga a iG+ l  +L k ga+vt+++r++ rl++ ++ nG
  EEA22441.1  9 LVIGATAgIGQALSSRLIKSGAKVTVVGRRKeRLDEfVRVNG 50
                57777544**************************99555555 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   5.5e-05     0.076       7      43 ..      14      46 ..       8      59 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 5.5e-05
                   TSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHH CS
  F420_oxidored  7 aGnmgealasgllaagaqpheivvansrnpekaeela 43
                   +  +g+al s+l+++g    +++v+  r +e+++e+ 
     EEA22441.1 14 TAGIGQALSSRLIKSG---AKVTVV-GRRKERLDEFV 46
                   4569************...****88.99999998875 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   3.2e-05     0.045       3      87 ..       8     123 ..       6     147 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 3.2e-05
                    EEEESTTSHHHHHHHHHCTTTSEEEEEE-TT...................T--TTSHHHHHHHHHHH--S......EEEE------HHHHHHSH.. CS
  RmlD_sub_bind   3 ilvtGanGqlGseLakqlaeeglevlaltre...................eldltdaeavaellkeakpd......vvvnaAAytavDkaEsee.. 71 
                     lv+Ga+  +G++L  +l ++g++v+ ++r+                   ++d+++ + + e+++++ ++      ++ na+  t +D a  e+  
     EEA22441.1   8 FLVIGATAGIGQALSSRLIKSGAKVTVVGRRkerldefvrvngeqsvrglQFDISNLDDIPEFVAQTMKQptdidsIIFNAGIQTPMDLADPEKfd 103
                    79**************************99989***********************9999999976544333455589999999999999877522 PP

                    ....HHHHHHHTHHHHHHHH CS
  RmlD_sub_bind  72 ....eaayavnaeavealAe 87 
                        +++++vn  +  alA+
     EEA22441.1 104 ltrfHEEMKVNFSSFVALAH 123
                    22223455666655555555 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   8.5e-05      0.12      14      63 ..       7      56 ..       3      76 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 8.5e-05
                  EEEEES-SH.HHHHHHHHHHCCT-CEEEEEESSHHHHHHHHHHHT.ET-EE CS
  Shikimate_DH 14 kvlliGaGe.maelvakhLlakgvkkvvvaNRtlerakelaeelkgeeiea 63
                  + l+iGa   +++ + + L+++g+k v+v++R  er +e+++  ++++++ 
    EEA22441.1  7 HFLVIGATAgIGQALSSRLIKSGAK-VTVVGRRKERLDEFVRVNGEQSVRG 56
                  5799999753788888999999999.**************97665554433 PP

>> THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   0.00026      0.37      38      78 ..       7      47 ..       3      49 .. 0.93

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00026
                   EEEEE---TTTHHHHHHHHHCTT-EEEEE-TTSCCHHHHHC CS
  THF_DHG_CYH_C 38 kvvvvGrsnivgkplallLleknatVtvchsktkdlaeitr 78
                   + +v+G+   +g++l+  L +++a Vtv+ ++ + l+e++r
     EEA22441.1  7 HFLVIGATAGIGQALSSRLIKSGAKVTVVGRRKERLDEFVR 47
                   679*****************************999999876 PP

>> DUF1776  Fungal family of unknown function (DUF1776)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.1   0.00021      0.28     114     195 ..     105     184 ..      99     185 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00021
     DUF1776 114 sswaselnerllspiltlqallplltsrakqkakiivvnpsissslnlpfhapEalvssalsalfevLkrelrphnidvtqi 195
                   +++e++ +++s++++  a+lp l +  + +++  +++ s ++ + ++  +  +    al+ ++  L+++lr+ ni+v +i
  EEA22441.1 105 TRFHEEMKVNFSSFVALAHAFLPYLLQ--NPSPTSFIFTGSNLAIVPAATLPAYSASKAALNVFTLCLREQLRHSNIKVLEI 184
                 6788999999***************99..478889999999999999999999999999********************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (261 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       460  (0.0256568); expected 358.6 (0.02)
Passed bias filter:                      449  (0.0250432); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 1966.42
//
Query:       EEA22442.1  [L=285]
Description: DUF1275 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.6e-44  151.5  14.3    3.4e-44  151.1  14.3    1.1  1  DUF1275         Protein of unknown function (DUF1275)
  ------ inclusion threshold ------
      0.012   16.1   0.0      0.018   15.4   0.0    1.2  1  Ribosomal_L32e  Ribosomal protein L32
       0.69    9.5   5.2        1.1    8.8   0.7    2.3  2  DUF4131         Domain of unknown function (DUF4131)


Domain annotation for each model (and alignments):
>> DUF1275  Protein of unknown function (DUF1275)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  151.1  14.3   5.8e-48   3.4e-44       2     192 .]      61     267 ..      61     267 .. 0.86

  Alignments for each domain:
  == domain 1  score: 151.1 bits;  conditional E-value: 5.8e-48
     DUF1275   2 llllafvaGllDavaflaaggvfvsaqTGNtvllglal.aegnakaala...alvsllaFvlGaalagllarrg..grrrrlvllle...allllaaal 91 
                 llll+f  G++Da++f +++++f+s+qTGNtv+l+la+ a++++++++     ++sl +F++Ga+++g+l+++   +r r++++ ++   ++++++aa+
  EEA22442.1  61 LLLLTFNIGIQDAATF-SDYRCFASNQTGNTVMLALAVvAQNDTSDLFIlanIGISLPLFLAGAFITGQLGNHVlgPRMRAWLVGINflqTMMVFCAAV 158
                 689*************.9*******************83555554444323355*****************9977544444444444787999999999 PP

     DUF1275  92 lvpagsvsp......lalallafamGlqnalfsr.lsgaeitttvlTgnltdlgidlarll.kkrklarnrrlaiilafllGavvGallvks...aaal 179
                 +  ++  ++       ++ llaf++G q++l sr l+ +eitt+++T++++dl+id++ +  ++r  +rnrr  ++l++++G++vGa+++ +     al
  EEA22442.1 159 MQFTLGGQSegpaalGIISLLAFSSGSQVVL-SRvLQIPEITTAMATAAWVDLMIDPKVWKiRNR--PRNRRSFFLLSLFAGSLVGAAVYYKagsPIAL 254
                 9665555449999988999************.999*************************98777..69*********************999****** PP

     DUF1275 180 wlaaallllvall 192
                 +l+a ++++v+++
  EEA22442.1 255 ILSASVKAIVTVM 267
                 **********986 PP

>> Ribosomal_L32e  Ribosomal protein L32
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.4   0.0   3.1e-06     0.018      22      74 ..      12      64 ..       7      76 .. 0.90

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 3.1e-06
                    ---TT-TTTTT-TTS-----GGG---TTTTT--TTS-EEEEESSGGGGTT--T CS
  Ribosomal_L32e 22 prGidnrvrrrfkgqilmpkiGYgspkktrgllpsGfkkvlVhnvkeLevllm 74
                    p+  + +++++f++q  +  + Y++++  r +    f  ++V++++eLe ll 
      EEA22442.1 12 PQNEQIEQHEKFQSQATVSATEYQQNRLSRSWRHYAFSPIIVNTLAELELLLL 64
                    5666677899***************************************9986 PP

>> DUF4131  Domain of unknown function (DUF4131)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   1.4     0.012        73      26      82 ..     129     199 ..     106     210 .. 0.61
   2 ?    8.8   0.7   0.00019       1.1      26      67 ..     192     260 ..     167     269 .. 0.70

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.012
     DUF4131  26 r.....rprrrv......llllllllllallgfalrapqpnandlsqlles...gqeviveGvvaslpelt 82 
                        pr r       +l  ++++++a+++f+l  ++ +   l  +  +   + + +v  +v+++pe+t
  EEA22442.1 129 LgnhvlGPRMRAwlvginFLQTMMVFCAAVMQFTLGGQSEGPAALGIISLLafsSGSQVVLSRVLQIPEIT 199
                 12334544444444566677778888888888888888877766665554477766666677888888876 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.00019
     DUF4131  26 r...........................rprrrvllllllllllallgfalrapqpnandlsqllesgq 67 
                                             r+r+r   +++ll l+a++ + + +++++ ++++ +l+ + 
  EEA22442.1 192 VlqipeittamataawvdlmidpkvwkiRNRPRNRRSFFLLSLFAGSLVGAAVYYKAGSPIALILSASV 260
                 255566666666666666677777888899*******************************99997633 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (285 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       619  (0.0345251); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.24s 00:00:00.70 Elapsed: 00:00:00.40
# Mc/sec: 2124.78
//
Query:       EEA22443.1  [L=457]
Description: FluG family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      7e-66  222.6   0.0    8.5e-66  222.3   0.0    1.1  1  Gln-synt_C  Glutamine synthetase, catalytic domain
  ------ inclusion threshold ------
       0.14   11.9   0.2        1.3    8.8   0.0    2.4  2  Gln-synt_N  Glutamine synthetase, beta-Grasp domain


Domain annotation for each model (and alignments):
>> Gln-synt_C  Glutamine synthetase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  222.3   0.0   9.5e-70   8.5e-66       2     344 ..     116     451 ..     115     452 .. 0.88

  Alignments for each domain:
  == domain 1  score: 222.3 bits;  conditional E-value: 9.5e-70
                 T-HHHHHHHHHHHH.HHTTCEEEEEEEEEEEEESEECCCESSEEEEEEE.TB...B.TSS-TTB..HCCCCCTCCHHHHHHHHHHHTT--EECCEEECC CS
  Gln-synt_C   2 rdPRsvlkralarl.aeeGltvvvgpElEFflfdkeedkeasksllevdseekgrpaekggyfs..vapvdeaedlrreivealealgieveashhEva 97 
                  +PRs l+   + + +e+G  +++g+E+E + ++++++++ s          +++ ++k + f   +++ ++ + ++++i + l a+gi++e++h+E a
  EEA22443.1 116 ECPRSRLRHISSLMvQETGHYPLIGFEIEVVFMQRVKNADGSVA--------TYQLTNKDHSFGslTTEDEQYMVMVEDIARSLLAAGIKIEQFHAEAA 206
                 69********9988799*******************99773233........3333334444430044455778899********************** PP

                 CTEEEEEE--EECHHHHHHHHHHHHHHHHHHHHTT-EEE-SSSSSTTS---BEEEEEEEEECTT.EESSB-TTSGGGB-HHHHHHHHHHHHHHHHHHHH CS
  Gln-synt_C  98 tgQvEinlkfadalkaaDnvvtfKrvvkevArkhgltatFmpKplegdnGsgmHvhlSlwdkdg.knlfadeddeyalselarhfigGllkhakaltal 195
                 +gQ E  l++  +++a+D+++  + ++  +A+k+ l+at++p+p e ++G+g Hvh+S    d+ ++l ++++  ++  e  ++f +G+l+ ++a++a+
  EEA22443.1 207 PGQWEFVLSPLRPVEAVDTLIKARSIISRTAEKYQLRATLFPRPSELHAGTGAHVHISCN-VDElSPLHSQDQ--KKQHEAQESFFAGILDQLPAILAF 302
                 ************************************************************.888466666655..679999****************** PP

                 HS-SCCHHHHCSSSTTS.SSBEEEESS-TTCSEEEE-TSGGCSTEEEECEBTTS-HHHHHHHHHHHHHHHHHTT-----...---S-SSSS-TTTHTSS CS
  Gln-synt_C 196 taptvnSYkRlvpgyea.PvalawgarNRsallRipaskekakrvElRlpdasaNPYLalAallaAgldGienklepge...pvekdlyelspeerkgi 290
                 t p+  SY R ++g ++ + ++awg +N++  lR ++     +++El+l+d+ aNPYLal allaAg+dG+++++++++   p   ++  l+++e++gi
  EEA22443.1 303 TLPQQESYARVQSGIWSgGEYAAWGWENKEIPLRRIE----HNHFELKLMDGFANPYLALCALLAAGMDGLKRGIQLSAgpcPRGANMLSLEEREKLGI 397
                 ****************9789**********9999888....89*********************************98654467789999999999998 PP

                 -B.--SSHHHHHHHHHCSHHHCCSS-HHHHHHHHHHHHHCHHHHHCT--HHHHHH CS
  Gln-synt_C 291 ee.lPasleeAlealeedellkevlgeevieaylalkraEleeleeevsdweler 344
                  + lP+sl+e+l+ l +++++ e++g+ +ie yla+kr E+e++++  +++e+++
  EEA22443.1 398 CTlLPKSLSESLDILVSNAVICETIGQAIIEPYLAIKRGEIEQVKT-WTEVERRN 451
                 7769***************************************864.56666655 PP

>> Gln-synt_N  Glutamine synthetase, beta-Grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.0     0.078     7e+02       2      37 ..      21      55 ..      20      56 .. 0.90
   2 ?    8.8   0.0   0.00015       1.3      53      82 ..      80     107 ..      80     108 .. 0.90

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.078
                --EEEEEEE-SSS-EEEEEEEHHHHHHHTTTT-EEE CS
  Gln-synt_N  2 vkfvdlqFtDikgklkhvtipadelsedaleegvsF 37
                ++fv +qF+  + ++   +ip++++ e+++++g  F
  EEA22443.1 21 TEFVLVQFMGYNANIFIRAIPVTRF-EHLIKNGQTF 55
                68999******99999999******.9999999877 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.00015
                 EEEEEEGGGEEE-SS-SS-.EEEEEEEEE- CS
  Gln-synt_N  53 mlLkPdlstavidPfreekktarvicdvyd 82 
                 ++LkPd+st+++ P +++   a+v++d+++
  EEA22443.1  80 CYLKPDISTLYVQPGSPHR--AIVVADIVQ 107
                 89************99977..999999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (457 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       362  (0.0201908); expected 358.6 (0.02)
Passed bias filter:                      356  (0.0198561); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 3131.63
//
Query:       EEA22444.1  [L=364]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-70  236.7   0.1    2.8e-70  236.4   0.1    1.1  1  DUF3431   Protein of unknown function (DUF3431)


Domain annotation for each model (and alignments):
>> DUF3431  Protein of unknown function (DUF3431)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  236.4   0.1   1.6e-74   2.8e-70       1     215 []      68     328 ..      68     328 .. 0.90

  Alignments for each domain:
  == domain 1  score: 236.4 bits;  conditional E-value: 1.6e-74
     DUF3431   1 lVvaklkee.dtsWveeelpdlqtaiYvvddp....saeltvpankGreamaYltyiidnYdsLpd.vvvFvhahraawhndaldydnaallrrlrlea 93 
                 lVva+++++ d+sW+++  +++++++Y+vd+p    s+ l+vp+n+G+eam+Ylt+iidnY ++p+  vvFvh++r+awhnd+++ydnaall++l+++a
  EEA22444.1  68 LVVARVAADgDASWIDSLSKKYHPCVYTVDAPmdpaSKYLQVPRNRGHEAMVYLTFIIDNYYHIPEaGVVFVHGSRWAWHNDEPTYDNAALLKALDVHA 166
                 8****************889**********77777999****************************99******************************* PP

     DUF3431  94 vqee.GYvnlrckwepg.Cp..............aelkplekeeeekkeeealaeafaelfeee.......evpevvaapcCaqFavsrerirkrpree 169
                 + e  GY+nlrc+w+++ Cp              a ++p++   +++ +++ l+ af+++f +          +++v+++cCaqF v r +i++++ +e
  EEA22444.1 167 ALEPwGYHNLRCDWRVStCPpsakpqgsmetsvqAMISPWD---ARAVSDSLLPGAFENIFGKVqsadsklGKHQTVRSQCCAQFIVGRVNILQHTIQE 262
                 ***************999**777776666655433355554...5567777**********44445677775699************************ PP

     DUF3431 170 Yvrlrqwllete.....lddelsGrvleylWhilFgk...............eavaCpdeeecycd 215
                 Y++lrqwll+ +      dd++sGr+l+ylWhilF k               ++ aCp++ +cyc+
  EEA22444.1 263 YIALRQWLLDESndaapRDDRISGRILSYLWHILFIKkqeveengaisleklNSAACPRAPDCYCR 328
                 **********7769999******************6669**************************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (364 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       377  (0.0210274); expected 358.6 (0.02)
Passed bias filter:                      301  (0.0167884); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.30s 00:00:00.82 Elapsed: 00:00:00.49
# Mc/sec: 2240.11
//
Query:       EEA22445.1  [L=319]
Description: aromatic ring-opening dioxygenase LigB subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-34  118.5   0.0    3.3e-34  118.2   0.0    1.0  1  LigB      Catalytic LigB subunit of aromatic ring-opening dio


Domain annotation for each model (and alignments):
>> LigB  Catalytic LigB subunit of aromatic ring-opening dioxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.2   0.0   1.8e-38   3.3e-34       2     256 ..      51     304 ..      50     316 .. 0.80

  Alignments for each domain:
  == domain 1  score: 118.2 bits;  conditional E-value: 1.8e-38
        LigB   2 alllsHvppilaavd.gkeqealrekvikgyesireriaeksPdtiivvsphhltdvnpvfvlgvaeefeaiddfg...kflprleyelkgnpeLaeki 96 
                 ++++sH+   +   + ++ ++ + +  +   ++i +    ++P++ii+v++h++td++ +  ++ +++ e  +d++   +  ++++y+++g+p +a+ i
  EEA22445.1  51 VICVSHGGGPMPLLGePGHKNMVNSWQTR-VRKILKLGTPEAPKAIILVTAHWTTDRP-T--ISSGAKHELYYDYYgfpPETYKIKYDAPGAPSIAKDI 145
                 68899975443444434555553332222.24444444445**************998.5..7999999*******99999****************** PP

        LigB  97 aealkksgidlavesnsmklDHGtlvPLelmlpdeakvpvikvslntvaypllsferlykLGeAlrkaveeldknvlilgsGgls.Hqlegdeaakada 194
                 ++ l+k+g+  +  +++++ DHG+++P++++ p    +  i+++ ++v     ++e++yk+G+ l++++    +n++i+gsG ++ H+l+   ++ + +
  EEA22445.1 146 YNRLQKAGFSPQL-DDKRGWDHGVFIPMKFIAP----DESIPIVQMSVL-ESEDPEEHYKIGQVLAELR---KENIAIVGSGFATfHNLRFFPRGSNFP 235
                 *************.*******************....455555555544.59*****************...9*********8876*999877776666 PP

        LigB 195 q.....tlllneefdeelldllkegrveelckmsk..eelsaaagheeeelvplvvalGalsgdkaelr 256
                       ++++ +++ e +++   ++r+++l+ +++   ++     h+ e++ pl+v +Ga s++k+ l 
  EEA22445.1 236 AdtaskVREWSNVLNEAVMTEDANDRMAKLKHWRNfpHAYTMHPPHGAEHFLPLIVTAGAGSSSKGGLY 304
                 677788888999999999999999*********9632455555567899*************9766555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (319 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       463  (0.0258241); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.46
# Mc/sec: 2096.04
//
Query:       EEA22446.1  [L=623]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.4e-05   24.1   1.0     0.0034   16.3   0.0    2.3  2  Fungal_trans_2  Fungal specific transcription factor domain
  ------ inclusion threshold ------
      0.031   14.0   0.0       0.06   13.1   0.0    1.4  1  DUF5435         Family of unknown function (DUF5435)


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   3.8e-07    0.0034       9     103 ..     187     288 ..     173     293 .. 0.76
   2 !    6.0   0.5   0.00051       4.5     291     354 ..     531     597 ..     364     603 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 3.8e-07
  Fungal_trans_2   9 nvapllspvpes.snpfrkvllplalsnk..allhallalsafhl......qskgpkds.lereakrykslalkelqealaelsstlsrnekykd 93 
                     ++a++l p  +s  ++ +kv+ + ++ ++   l++ l+  s++hl      + ++++++  e e+ +y+++al+el++a a ++  ++   + + 
      EEA22446.1 187 HFARILIPTLRSdVDYSHKVFTEYIQLTPdpLLFNVLCLSSSVHLdklmlwNGLDSDSRrRELEQSHYRYTALRELRRAVASPKIGTP---EFDG 278
                     455555555555556666777777766668566666666678999**9999555555555699*************************...9999 PP

  Fungal_trans_2  94 iLaaiLllcs 103
                     iL +i ll +
      EEA22446.1 279 ILLSICLLAV 288
                     9999977655 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.00051
  Fungal_trans_2 291 lvkkllellellpsspvaiasLlWplFiaGceavde..ddRdfvrrrleeleqsrl..gnvrrarqvl 354
                     + + + ++   l+ +p+  +  lW+  iaG++a+d   ++R++++ +  +l+ +rl  +   ++ +v+
      EEA22446.1 531 IRDTISNCEYALQHNPWVLRLQLWCVVIAGIAAEDIdtELRQWMALKAHDLC-TRLslQQWDEVVNVM 597
                     33344444444558888777777**********99999*************9.555336555555555 PP

>> DUF5435  Family of unknown function (DUF5435)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   6.7e-06      0.06       8      41 ..       6      39 ..       3      62 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 6.7e-06
     DUF5435  8 rihvlrpttinvevrprreslrrqllsqlffkkm 41
                 i v  pt in+ +r  r  lr ql+ ++++kk 
  EEA22446.1  6 FIFVNAPTIINAGPRDARRQLRSQLMRRVYLKKY 39
                58999**************************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (623 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       546  (0.0304535); expected 358.6 (0.02)
Passed bias filter:                      437  (0.0243739); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.45
# Mc/sec: 4166.18
//
Query:       EEA22447.1  [L=74]
Description: hypothetical protein PMAA_090760 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
  ------ inclusion threshold ------
        4.7    6.4  14.7          5    6.3  14.7    1.0  1  NOA36        NOA36 protein


Domain annotation for each model (and alignments):
>> NOA36  NOA36 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3  14.7   0.00028         5     249     300 ..      16      67 ..       3      73 .. 0.73

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.00028
       NOA36 249 ddeedsdydaylkalasgddeddegdedddddddeedddeeeddedeeeeee 300
                 dde+dsd ++ l+++ s++ +dde+++d + d++e+dd+++ dd+d +++ e
  EEA22447.1  16 DDESDSDTSSILSQIFSDNGSDDESASDLESDNQESDDESDSDDDDLHDKVE 67 
                 4577888888888888888899999999988888888888777777665544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (74 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       943  (0.0525964); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.45
# Mc/sec: 498.04
//
Query:       EEA22448.1  [L=416]
Description: hypothetical protein PMAA_090770 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.9e-65  219.8   0.0    3.7e-64  217.2   0.0    1.9  1  DUF3435   Protein of unknown function (DUF3435)


Domain annotation for each model (and alignments):
>> DUF3435  Protein of unknown function (DUF3435)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  217.2   0.0   2.1e-68   3.7e-64       1     214 [.      51     252 ..      51     254 .. 0.99

  Alignments for each domain:
  == domain 1  score: 217.2 bits;  conditional E-value: 2.1e-68
     DUF3435   1 ieDllellrvlltttekrfqlgrqrvqlllllllaaftsnRpgalleLryrDleltlikdPeggrpvllvevtpeftKgklGkkkkntfvlPeiiydps 99 
                 ieD+ e++rvll+tte +f +g+ r qll++ +la +t++Rp all+L+y+Dl l+li+dPeggrp+l++ ++p+ftK++lGkk +             
  EEA22448.1  51 IEDVSEFTRVLLSTTETSFGCGWRRTQLLFYTQLAVITVSRPRALLHLCYQDLGLRLIRDPEGGRPNLFIFLKPDFTKRFLGKKAP------------- 136
                 8*************************************************************************************............. PP

     DUF3435 100 LvlsPhvfllgllfrdeAFks.....psltsaedlyrlkvpkgrqqlpLklkpemldipvFcraereaegvrilkdealtastlnsrlkrlgeiagfee 193
                      hv+ll++lf++e+Fk+     p+l+ a++ly++ + +g +q+ Lklk+e+l+ +vFc++ere +g+ri+ ++++  stl+s+++r+gei++fe+
  EEA22448.1 137 ----LHVCLLSMLFHIEGFKRitetgPVLDNAKKLYSVGIVDGLNQQDLKLKDEILNKYVFCQVERETTGYRIVLEKRMLSSTLRSQMRRVGEITTFED 231
                 ....79********************************************************************************************* PP

     DUF3435 194 pitpYklRrgaakalneSgev 214
                 +++pY l ++aak++n+Sg++
  EEA22448.1 232 IVKPYLLWYAAAKEFNNSGNT 252
                 ******************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (416 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       523  (0.0291706); expected 358.6 (0.02)
Passed bias filter:                      486  (0.0271069); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 2700.12
//
Query:       EEA22449.1  [L=394]
Description: dimeric dihydrodiol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.9e-17   63.2   0.1    6.3e-17   62.5   0.1    1.3  1  GFO_IDH_MocA    Oxidoreductase family, NAD-binding Rossmann f
  ------ inclusion threshold ------
      0.035   14.8   0.1      0.066   13.9   0.1    1.4  1  NAD_binding_3   Homoserine dehydrogenase, NAD binding domain
       0.13   12.3   0.1       0.37   10.8   0.0    1.8  2  GFO_IDH_MocA_C  Oxidoreductase family, C-terminal alpha/beta 


Domain annotation for each model (and alignments):
>> GFO_IDH_MocA  Oxidoreductase family, NAD-binding Rossmann fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.5   0.1   1.1e-20   6.3e-17       2     116 ..       7     133 ..       6     136 .. 0.86

  Alignments for each domain:
  == domain 1  score: 62.5 bits;  conditional E-value: 1.1e-20
                   EEEEETTSHHHHHHHHHHHHTTTTE.......EEEEEEC.SSHHHHHHHHHHTTHE....EESSHHHHHTCTTESEEEE-S-GGGHHHHHHHHHHTT CS
  GFO_IDH_MocA   2 rvaiiGaGkigskhlrplnesqrle.......evvalld.pdaeraeavaesfgve....aysdleelladpeidavivatpngtheelakaaleag 86 
                   r++i  +G++++k++  l + ++          v+a+ + ++ +ra+++ +++g++    ay ++eel++dp++d+++va+p ++h++ ++ alea+
    EEA22449.1   7 RWGILATGRVAKKFVHDLLKDTKSRsaedishTVTAVASsSSIARAKEFIRETGLPdnlvAYGSYEELVKDPNVDVIYVASPHSHHYQNVRLALEAN 103
                   56777778887777666655544445788888777776515679***************************************************** PP

                   -EEEEESSS-SSHHHHHHHHHHHHHHTS-E CS
  GFO_IDH_MocA  87 khvllEKPlattveeakelvelaekkgklv 116
                   khvl+EK ++ + ++ak lv+la++++  +
    EEA22449.1 104 KHVLCEKAFTVNAAQAKILVDLARSRNLFL 133
                   ************************998765 PP

>> NAD_binding_3  Homoserine dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.1   1.1e-05     0.066       3     109 ..      14     128 ..      13     134 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.1e-05
                    SHHHHHHHHHHHH---S.....SEEEEEEEEESSEEE-TT...HHHHHT--CB.---HHHHHHHHS-EEEEE-S--HHHHTTHHHHHHTTEEEE-S CS
  NAD_binding_3   3 GaiGsavleqlkrqqse.....ielelvavadrdsllskd...rkallaseal.tldlddliahldpdvvVEcasseavaelvlkaLkagkdvvta 89 
                    G ++++++  l+++++      i+ ++ ava ++s ++++   r+  l++  + + + ++l++++++dv+  + +++   + v  aL+a+k+v+  
     EEA22449.1  14 GRVAKKFVHDLLKDTKSrsaedISHTVTAVASSSSIARAKefiRETGLPDNLVaYGSYEELVKDPNVDVIYVASPHSHHYQNVRLALEANKHVLC- 108
                    889999888777666666999*************555555688888888775426789999998899988777777777788999*******985. PP

                    --CGGG.-HHHHHHHTSSSTT CS
  NAD_binding_3  90 nkgala.dealyeeLreaaea 109
                      +a++ + a+ + L+++a++
     EEA22449.1 109 -EKAFTvNAAQAKILVDLARS 128
                    .46666688888888888876 PP

>> GFO_IDH_MocA_C  Oxidoreductase family, C-terminal alpha/beta domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0      0.72   4.3e+03      47      68 ..      89     110 ..      88     134 .. 0.74
   2 ?   10.8   0.0   6.2e-05      0.37       2      50 ..     150     198 ..     149     202 .. 0.93

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.72
                     CHHHHHHHHHHHTSEEEEEEEE CS
  GFO_IDH_MocA_C  47 giHdiDllqwLfGqppsvvaal 68 
                     ++H++  +++ + ++++v    
      EEA22449.1  89 HSHHYQNVRLALEANKHVLCEK 110
                     6899999999999999887654 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 6.2e-05
                     HHHHTTTTSSEEEEEEEEECBEEECHHHHCCGGSH...HCSTSHHHHTCHHH CS
  GFO_IDH_MocA_C   2 elIengklGevvsvdvwtldtragaeakkrwkrrk...kksgGvlgdlgiHd 50 
                       I++g++Gevv v   + d++ g+ + ++ ++r+      gG+l d+gi+ 
      EEA22449.1 150 DIIKQGEIGEVVRV---VADNSIGNTKGWDANHRMvnlDLAGGALLDMGIYS 198
                     579***********...8*****************999999********985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (394 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       465  (0.0259356); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.45
# Mc/sec: 2626.15
//
Query:       EEA22450.1  [L=1286]
Description: ATP-binding cassette transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.4e-38  131.3   0.0    7.2e-18   65.4   0.0    2.4  2  ABC_tran       ABC transporter
    2.9e-37  128.8  22.3    1.2e-22   80.9   9.2    2.3  2  ABC_membrane   ABC transporter transmembrane region
    2.4e-10   40.2   0.1     0.0016   17.9   0.0    3.4  3  SMC_N          RecF/RecN/SMC N terminal domain
    2.6e-08   34.1   1.2       0.33   10.7   0.8    3.7  3  AAA_21         AAA domain, putative AbiEii toxin, Type IV TA 
      1e-07   32.3   0.6      0.039   14.2   0.0    3.8  3  AAA_22         AAA domain
    4.7e-07   29.1   0.1     0.0008   18.6   0.0    2.4  2  T2SSE          Type II/IV secretion system protein
    9.2e-06   26.1   1.3       0.23   11.8   0.6    3.3  2  AAA_16         AAA ATPase domain
     0.0001   22.0   0.5      0.011   15.4   0.2    2.7  2  AAA_29         P-loop containing region of AAA domain
    0.00022   20.8   0.1       0.36   10.4   0.1    2.7  2  AAA_25         AAA domain
    0.00036   20.5   1.1       0.91    9.4   0.1    2.6  2  RsgA_GTPase    RsgA GTPase
    0.00074   19.7   0.2        1.2    9.4   0.0    3.2  2  SbcCD_C        Putative exonuclease SbcCD, C subunit
     0.0018   17.7   0.1       0.18   11.1   0.0    2.4  2  DnaB_C         DnaB-like helicase C terminal domain
     0.0018   17.8   0.4       0.33   10.4   0.1    2.3  2  AAA_7          P-loop containing dynein motor region
     0.0018   17.9   0.7       0.34   10.5   0.0    2.6  2  cobW           CobW/HypB/UreG, nucleotide-binding domain
      0.002   17.5   1.2      0.043   13.2   0.2    2.3  2  FtsK_SpoIIIE   FtsK/SpoIIIE family
     0.0021   18.0   4.2       0.35   10.8   0.0    3.1  2  NACHT          NACHT domain
     0.0022   18.0   0.3       0.35   10.9   0.0    3.3  3  CbiA           CobQ/CobB/MinD/ParA nucleotide binding domain
     0.0025   17.6   0.1        2.4    7.9   0.0    2.9  2  DEAD           DEAD/DEAH box helicase
     0.0028   17.8   0.0        1.9    8.6   0.0    2.5  2  AAA_33         AAA domain
     0.0036   16.6   0.1        2.5    7.3   0.0    2.4  2  Zeta_toxin     Zeta toxin
     0.0043   17.5   0.8       0.83   10.1   0.1    3.5  3  AAA            ATPase family associated with various cellular
     0.0043   17.1   0.1        1.9    8.5   0.0    2.4  2  ResIII         Type III restriction enzyme, res subunit
     0.0056   16.8   0.6      0.013   15.6   0.0    1.9  1  DUF87          Helicase HerA, central domain
      0.008   15.6   0.2        2.7    7.3   0.0    2.7  2  Mg_chelatase   Magnesium chelatase, subunit ChlI
  ------ inclusion threshold ------
      0.011   15.8   0.0       0.28   11.3   0.0    2.5  2  MMR_HSR1       50S ribosome-binding GTPase
      0.025   15.1   0.2        2.3    8.7   0.0    2.4  2  AAA_23         AAA domain
      0.027   14.2   0.9        5.7    6.6   0.0    3.0  3  IstB_IS21      IstB-like ATP binding protein
      0.027   13.9   0.5       0.74    9.2   0.1    2.8  3  PhoH           PhoH-like protein
       0.04   12.8   1.2       0.28   10.0   0.1    2.2  2  TrwB_AAD_bind  Type IV secretion-system coupling protein DNA-
      0.045   13.8   0.5          4    7.4   0.1    2.5  2  TsaE           Threonylcarbamoyl adenosine biosynthesis prote
       0.05   13.3   0.1        1.8    8.2   0.0    2.4  2  AAA_30         AAA domain
      0.055   13.3   2.1      0.055   13.3   0.1    2.1  1  DUF2474        Protein of unknown function (DUF2474)
      0.063   12.5   0.3        9.6    5.3   0.1    2.2  2  DUF2075        Uncharacterized conserved protein (DUF2075)
       0.13   12.2   3.8        1.1    9.3   0.2    3.0  2  AAA_5          AAA domain (dynein-related subfamily)
       0.14   12.1   0.0        5.1    6.9   0.0    2.9  3  ATPase_2       ATPase domain predominantly from Archaea
       0.14   12.2   0.2         21    5.2   0.0    3.1  3  AAA_14         AAA domain
       0.16   11.2   0.1       0.68    9.2   0.0    1.8  2  Septin         Septin
       0.19   10.8   1.0        7.3    5.7   0.1    2.5  2  NB-ARC         NB-ARC domain
       0.42   10.3   2.4         11    5.7   0.4    2.7  2  PduV-EutP      Ethanolamine utilisation - propanediol utilisa
       0.93    9.4   2.5        3.7    7.4   0.3    2.5  2  MobB           Molybdopterin guanine dinucleotide synthesis p


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.4   0.0   1.6e-20   7.2e-18       1     136 [.     452     588 ..     452     589 .. 0.88
   2 !   63.6   0.0     6e-20   2.7e-17       1     136 [.    1044    1213 ..    1044    1214 .. 0.87

  Alignments for each domain:
  == domain 1  score: 65.4 bits;  conditional E-value: 1.6e-20
                 EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.......HHHTCHHHHHHHS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxxx RF
    ABC_tran   1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren.......esdeeiekalskl 92 
                 l++v ++l++ge+v   G  G+GK+ L+++++g+ + t G+i            ++++kei++++qep l + +t+r+         + e+ +++++  
  EEA22450.1 452 LRDVCIDLNRGEIVICAGAVGSGKTMLAMAILGEAHLTTGTI------------RVSSKEIAYCSQEPWLPS-VTIRDAisgggldLDLEWYNTVIDAC 537
                 5788899***********************************............7999*********77755.55****99999985556677777777 PP

                 TTGG.......TTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTT CS
                 xxxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  93 glke.......lkdtvvksspssLSgGqkqrvalarallkkpkllllDEpt 136
                 gl+         + t +++++ +LSgGqkqr+alara+ ++ ++l+lD+p+
  EEA22450.1 538 GLVPdfttfarGDMTLIENNGINLSGGQKQRIALARAVYSRHRILVLDDPF 588
                 777777777776778888888*****************************7 PP

  == domain 2  score: 63.6 bits;  conditional E-value: 6e-20
                  EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCH.CEEEE-SS--S-TTSBHHHH......HHHTCHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxx RF
    ABC_tran    1 lknvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrk.eigvlpqepqlfpeltvren......esdeeiekals 90  
                  l+nvsl++++g+k+ +vG++G+GKStL+ +l++ll+  +G+i++d+ d+++++l+ lr+  +  +pq+ +  p  ++r n      +s+e+i  al+
  EEA22450.1 1044 LRNVSLSINPGQKLIVVGRTGSGKSTLMLTLLQLLNTRQGSIWIDDVDITQIPLRTLRQrGFIAVPQDGFNVPSASLRFNldpyhmNSEEDIVMALK 1140
                  78*************************************************8877776516889****9999999999999***9999999999999 PP

                  HSTTGG......................TTCBGESTTSGGS-HHHHHHHHHHHHHHH......TSSEEEEESTT CS
                  xxxxxx......................xxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxx RF
    ABC_tran   91 klglke......................lkdtvvksspssLSgGqkqrvalarallk......kpkllllDEpt 136 
                  ++g+ e                      l d+++ s    +S Gq q  al+r+ll+       +++++lDE++
  EEA22450.1 1141 RVGIWEriwltygdptcetagasadvgrLLDSPI-SLFLPFSAGQLQLFALCRTLLRvksnalTKPIIILDEAS 1213
                  9999999999999999999999997777777776.56699***************9733333346799999986 PP

>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.5   5.2     6e-17   2.7e-14      12     270 ..     126     386 ..     114     389 .. 0.82
   2 !   80.9   9.2   2.6e-25   1.2e-22      13     238 ..     721     944 ..     712     979 .. 0.91

  Alignments for each domain:
  == domain 1  score: 53.5 bits;  conditional E-value: 6e-17
                   HHHHHHHHHHHHHHHHHHHSSTCCHH......HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHHHHSCHHHHHH CS
  ABC_membrane  12 gvlsplfplvlgrildtlldkgdpet......ealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsffdtnsvGells 102
                    +   l+p+++g  +++  +  +++t          ++ l+ ++++l++++++  +++ +n +   ++ +l + + +  l+++       + +e l+
    EEA22450.1 126 ILFTYLQPIFIGVAINFCKGP-TSHTsdttsaDSGLRLVLFSAIVYLGMAVSGPTYQHQINRLRVMTRGALISLVHHQSLHMS---TTGSKDSEALT 218
                   445556677777777666553.2222355565667778888888888888888888888888888888888888888888874...3459999**** PP

                   HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHTTTH CS
  ABC_membrane 103 rltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirtVkafgre 199
                   ++++d+++++++  +++ ++ + l +++g+++++  +gw ++++ l+i++ +  vsa++ak+l  ++k+ + a+ k+ + +  +l gi+ +k +g+e
    EEA22450.1 219 LVSSDIDNIESFGETFHETWARLLEVIIGTMLLAAQIGW-FAFLPLVIVFGCSRVSAYVAKHLDGMQKDWNVATQKRLATVAAALGGIKSLKMMGME 314
                   ***************************************.8999999************************************************** PP

                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHTTSSTHHHHHHHHHHHHHH CS
  ABC_membrane 200 eyflekfekaleeakkagikkaianglligitqllgllsyalal.wfGttlvisgelsvgdlvvflslfail 270
                   +++++ +   + e+  ++++   +    ++ +++lg ++ +l+l +++ tl   g l  +++++ ++l++++
    EEA22450.1 315 DAVQSLISYLRSEEIGSSKRLRWILVTYNASANALGIFAPVLTLiLYALTLENGGVLRADEVFTSVALLTMV 386
                   **************9999888888888888888888888888875567777777899999988888887765 PP

  == domain 2  score: 80.9 bits;  conditional E-value: 2.6e-25
                   HHHHHHHHHHHHHHHHHHSSTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHHHHHHHHHCSTHHHHHHSCHHHHHHHHHHHH CS
  ABC_membrane  13 vlsplfplvlgrildtlldkgdpetealnvysllllllglaqfilallqsyll.nvtgerlskrlrrklfkkilrqpmsffdtnsvGellsrltndv 108
                   +++ +   + ++il++ ++ + pe+  l++y+ l++++ ++ ++++ +  +   ++++ r  + l+++l++++lr+p+s+f +++vG +l+r+  d+
    EEA22450.1 721 AAYSFCLTFSQYILKWATE-SPPEK--LKIYMALYAAISFIAWVATNGTMWSTqIKIAVRSGTVLHAQLLERVLRAPLSYFTQTDVGAILNRFGQDI 814
                   4555666677788888887.88888..99999999999999999998888887788***************************************** PP

                   HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHTTTHHHHHHH CS
  ABC_membrane 109 sklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirtVkafgreeyflek 205
                   + ++  l+  l  +   ++ +++ l++++ +++ + + + +++  ++++++++ +++++l+  + ++++++++ + ++ sg+ t++afg+ e+f ++
    EEA22450.1 815 NLVDKQLPPALANLNNQIFKLLMQLVLLLRVQPIMVVTVPSCFMSVYFIQKIYLRTSRQLRFLDLESRSQLYTSFLDTTSGVTTIRAFGWKEKFKDE 911
                   ************************************************************************************************9 PP

                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  ABC_membrane 206 fekaleeakkagikkaianglligitqllglls 238
                      a++  +k  +  + ++ +l +++++l+ ++
    EEA22450.1 912 NIRAIDISQKPFYLLLCLQCWLKVVLDCLMAII 944
                   999999999999999999999888888888776 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   0.0   0.00027      0.12      76     184 ..     273     604 ..     266     636 .. 0.90
   2 ?    6.3   0.0     0.013       5.9      20      50 ..    1049    1080 ..    1038    1087 .. 0.74
   3 !   17.9   0.0   3.6e-06    0.0016     136     205 ..    1179    1250 ..    1115    1266 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00027
                 EEEEEEEEEETTEESSSSSSCEEEEEEEETTSEEEEEETTEEE-HHHHHHHHHCTT-STT....................................... CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....................................... RF
       SMC_N  76 kaeveitfdnedkklkiekeevsisrrvkrkgeseykingkevtkkevsellesagiske....................................... 135
                 +a+v+ ++d  +k+ ++ +++   ++ +  +g  + k+ g e   + + + l+s++i ++                                       
  EEA22450.1 273 SAYVAKHLDGMQKDWNVATQKRLATVAAALGGIKSLKMMGMEDAVQSLISYLRSEEIGSSkrlrwilvtynasanalgifapvltlilyaltlenggvl 371
                 688888888888888888888888888888888899999999999999999999999999999999999999999999999999999999999999999 PP

                 ................................................................................................... CS
                 ................................................................................................... RF
       SMC_N 136 ................................................................................................... 135
                                                                                                                    
  EEA22450.1 372 radevftsvalltmvthpanmvmtlipqaiaimanfdrvqsyvsqpsiqdkreysaesnvrklasiqnvsitspstsltllrdvcidlnrgeivicaga 470
                 99999999999999999999999999999999999999999999999999999999999999999999999999999999999999999********** PP

                 .........................................................................................CS-HHHHHHH CS
                 .........................................................................................xxxxxxxxxx RF
       SMC_N 136 .........................................................................................lLSgGektLv 145
                                                                                                          +LSgG+k+ +
  EEA22450.1 471 vgsgktmlamailgeahlttgtirvsskeiaycsqepwlpsvtirdaisgggldldlewyntvidacglvpdfttfargdmtlienngiNLSGGQKQRI 569
                 ************************************************************************************************987 PP

                 HHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 146 alaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellk 184
                 ala       ++++ + +lD+  +a+D k v ++  +l 
  EEA22450.1 570 ALA----RAVYSRHRILVLDDPFSAIDGKTVDRIIGRLL 604
                 765....55789999****************99876654 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.013
                  EETTSSEE.EEEESTTSSHHHHHHHHHHHCTT CS
                  xxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N   20 lpfsksft.aivGpNGSGKsnlldAilFvLGe 50  
                  l ++++ + ++vG+ GSGKs l+  +l +L +
  EEA22450.1 1049 LSINPGQKlIVVGRTGSGKSTLMLTLLQLLNT 1080
                  555555541579**********9888777765 PP

  == domain 3  score: 17.9 bits;  conditional E-value: 3.6e-06
                  CS-HHHHHHHHHH.HHHH.HHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC- CS
                  xxxxxxxxxxxxx.xxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  136 lLSgGektLvala.LlfA.iqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQfivislreemleka 205 
                   +S G+ +L al   l+    ++  +p+ +lDe  + LD +  +++++ll+ +  +  +++i++r e + ka
  EEA22450.1 1179 PFSAGQLQLFALCrTLLRvKSNALTKPIIILDEASSSLDPETESILVDLLRDDLRDHTVVIIAHRLEGFIKA 1250
                  6899****999852333414556689***************************************8877776 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.6   0.0    0.0032       1.4     184     298 ..     409     623 ..     401     627 .. 0.71
   2 !   10.2   0.0    0.0011      0.48       3      26 ..    1058    1083 ..    1057    1132 .. 0.73
   3 !   10.7   0.8   0.00074      0.33     237     294 ..    1180    1239 ..    1166    1244 .. 0.86

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0032
      AAA_21 184 llqrlvrslklveielsdlgegeeliasvderlrer............................................................... 219
                 ++q +v++++ ++ + +  +  +++ as++++++ +                                                               
  EEA22450.1 409 RVQSYVSQPSIQDKREYSAESNVRKLASIQNVSITSpstsltllrdvcidlnrgeivicagavgsgktmlamailgeahlttgtirvsskeiaycsqep 507
                 556666666666666666666666666666666666666666666666666666666666666666666666666666666666666666777777777 PP

      AAA_21 220 ..................................gvvflengdgqelparel..SdGtkrllalltallralkkgsllliDEpEngLHPkllrrllell 282
                                                   +++++ +gd   +  + +  S G+k+ +al+ a+++++   ++l++D+p + ++ k + r+++ l
  EEA22450.1 508 wlpsvtirdaisgggldldlewyntvidacglvpDFTTFARGDMTLIENNGInlSGGQKQRIALARAVYSRH---RILVLDDPFSAIDGKTVDRIIGRL 603
                 777777777777777777777777777778888888888888888888888888******************...*********************655 PP

      AAA_21 283 ....kelsrngaQviltTHS 298
                      +l+r  + v+l T S
  EEA22450.1 604 lstrGLLKRMATTVFLITNS 623
                 25553333345567777765 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.0011
      AAA_21    3 vliGpNgsGKSnLLdaldllarl..d 26  
                  +++G+ gsGKS+L+ +l  l  +   
  EEA22450.1 1058 IVVGRTGSGKSTLMLTLLQLLNTrqG 1083
                  69***************999765331 PP

  == domain 3  score: 10.7 bits;  conditional E-value: 0.00074
      AAA_21  237 lSdGtkrllalltallralkkg...sllliDEpEngLHPkllrrllellkelsrngaQvil 294 
                  +S G+++l+al   llr  + +   +++++DE  ++L+P+  + l++ll++  r +  v++
  EEA22450.1 1180 FSAGQLQLFALCRTLLRVKSNAltkPIIILDEASSSLDPETESILVDLLRDDLR-DHTVVI 1239
                  499**************99999***************************66555.566655 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.8   0.2    0.0042       1.9       5      29 ..     462     486 ..     457     501 .. 0.84
   2 !   14.2   0.0   8.6e-05     0.039       8      36 ..    1057    1085 ..    1052    1124 .. 0.81
   3 ?    4.6   0.0     0.081        36      78     119 ..    1191    1233 ..    1141    1245 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0042
      AAA_22   5 agilvvtGesGtGKTtllrrlleql 29 
                   i+++ G +G+GKT+l+  +l ++
  EEA22450.1 462 GEIVICAGAVGSGKTMLAMAILGEA 486
                 6789*************98877665 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 8.6e-05
      AAA_22    8 lvvtGesGtGKTtllrrlleqldeeakae 36  
                  l+v+G +G+GK+tl+ +ll+ l+ ++   
  EEA22450.1 1057 LIVVGRTGSGKSTLMLTLLQLLNTRQGSI 1085
                  79******************998776555 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.081
      AAA_22   78 llealeqalraravielliiDEaqh.lrseealeeLrsllnl..s 119 
                  ++++l+  ++a  + +++i+DEa   l  +e  + L++ll +  +
  EEA22450.1 1191 CRTLLRVKSNALTK-PIIILDEASSsL-DPETESILVDLLRDdlR 1233
                  44666666666666.**********99.77777777777776432 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   0.0     0.003       1.4     127     154 ..     460     487 ..     397     497 .. 0.77
   2 !   18.6   0.0   1.8e-06    0.0008     105     160 ..    1029    1085 ..    1019    1096 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.003
       T2SSE 127 rerglilvsGgTgsGKttllyallkein 154
                 ++  +++ +G+ gsGKt l+ a+l e +
  EEA22450.1 460 NRGEIVICAGAVGSGKTMLAMAILGEAH 487
                 455678889**************99876 PP

  == domain 2  score: 18.6 bits;  conditional E-value: 1.8e-06
       T2SSE  105 lddlgaeealk.ekiaevlrkavrerglilvsGgTgsGKttllyallkeinksderi 160 
                  l++++a+ +++ +   + ++ +++  + ++v G TgsGK+tl+ +ll+ +n+++  i
  EEA22450.1 1029 LEEVSASYSQSlKLALRNVSLSINPGQKLIVVGRTGSGKSTLMLTLLQLLNTRQGSI 1085
                  5555555444424445667778888899************************96665 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.7   0.0    0.0011       0.5      22      69 ..     460     502 ..     449     605 .. 0.74
   2 !   11.8   0.6   0.00052      0.23      25      57 ..    1055    1088 ..    1038    1240 .. 0.49

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.0011
      AAA_16  22 grpelvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipy 69 
                 +r+e+v++ G+ G+GK+ l+ ++l +     +++++g+ + ++++i+y
  EEA22450.1 460 NRGEIVICAGAVGSGKTMLAMAILGE-----AHLTTGTIRVSSKEIAY 502
                 3459****************999953.....55556666666666666 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 0.00052
      AAA_16   25 elvllsGesGvGKsslvrellralekd.ggiflr 57  
                  + ++++G  G+GKs+l+ +ll+ l+++ g i++ 
  EEA22450.1 1055 QKLIVVGRTGSGKSTLMLTLLQLLNTRqGSIWID 1088
                  4589*****************9888883233332 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0       0.1        47      15      38 ..     455     478 ..     450     484 .. 0.77
   2 !   15.4   0.2   2.5e-05     0.011      15      46 ..    1047    1078 ..    1043    1084 .. 0.78

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.1
      AAA_29  15 htieidlkgatlltGpsGsGKSTl 38 
                   i++++ ++++ +G+ GsGK+ l
  EEA22450.1 455 VCIDLNRGEIVICAGAVGSGKTML 478
                 5677776669999********866 PP

  == domain 2  score: 15.4 bits;  conditional E-value: 2.5e-05
      AAA_29   15 htieidlkgatlltGpsGsGKSTllDAiqalL 46  
                   +++i++ +  +++G++GsGKSTl+  +  lL
  EEA22450.1 1047 VSLSINPGQKLIVVGRTGSGKSTLMLTLLQLL 1078
                  5677888779999***********95555555 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.4   0.1   0.00079      0.36      28      53 ..     458     482 ..     433     494 .. 0.81
   2 !    7.3   0.0    0.0072       3.2      31      54 ..    1052    1075 ..    1036    1099 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00079
      AAA_25  28 gllpagelallaGapgtGKttlaldl 53 
                 +l  +ge+++ aGa g+GKt+la+ +
  EEA22450.1 458 DL-NRGEIVICAGAVGSGKTMLAMAI 482
                 45.89******************976 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0072
      AAA_25   31 pagelallaGapgtGKttlaldla 54  
                    g   +++G++g+GK+tl l l 
  EEA22450.1 1052 NPGQKLIVVGRTGSGKSTLMLTLL 1075
                  568889*************99874 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.0   0.1    0.0028       1.2      90     134 ..     452     497 ..     415     499 .. 0.75
   2 !    9.4   0.1     0.002      0.91      99     129 ..    1053    1084 ..    1030    1092 .. 0.79

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.0028
                  HHHHHHHCTT.SEEEEECSTTSSHHHHHHHHCTT-----S------ CS
  RsgA_GTPase  90 leelkellkd.ktsvlvGqSGvGKStLinallpelelktgevsekl 134
                  l+++   l+  ++++ +G  G GK+ L  a+l+e++l tg ++ ++
   EEA22450.1 452 LRDVCIDLNRgEIVICAGAVGSGKTMLAMAILGEAHLTTGTIRVSS 497
                  44555555555999***************************99765 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.002
                   T.SEEEEECSTTSSHHHHHHHHCTT-----S- CS
  RsgA_GTPase   99 d.ktsvlvGqSGvGKStLinallpelelktge 129 
                     +  ++vG +G GKStL+ +ll+ l+++ g+
   EEA22450.1 1053 PgQKLIVVGRTGSGKSTLMLTLLQLLNTRQGS 1084
                   4478899************9999877766665 PP

>> SbcCD_C  Putative exonuclease SbcCD, C subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.4   0.0    0.0027       1.2      32      86 ..     560     601 ..     546     604 .. 0.75
   2 ?    6.6   0.0      0.02       8.8      63      89 ..    1203    1229 ..    1181    1230 .. 0.77

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0027
     SbcCD_C  32 tlSGGekqflaylalaaalaalyssaegrepalrlvfLDEAFsklDeesiatlle 86 
                 +lSGG+kq    +ala   +a+ys+        r+++LD+ Fs +D+++++++++
  EEA22450.1 560 NLSGGQKQR---IALA---RAVYSR-------HRILVLDDPFSAIDGKTVDRIIG 601
                 677777743...3344...556666.......49***************999875 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.02
     SbcCD_C   63 alrlvfLDEAFsklDeesiatllelle 89  
                  +  +++LDEA s+lD+e+ + l++ll+
  EEA22450.1 1203 TKPIIILDEASSSLDPETESILVDLLR 1229
                  45689*************999999987 PP

>> DnaB_C  DnaB-like helicase C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.1   0.0    0.0004      0.18       6      55 ..     449     497 ..     446     507 .. 0.76
   2 ?    3.8   0.0     0.066        30      15      45 ..    1050    1080 ..    1042    1108 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.0004
                 THHHHHHCTSBXTTXEEEEEEXTTSSHHHHHHHHHHHHHHCSTSEEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      DnaB_C   6 fkdLDkltsGlqkgdliiiAarpsmGktalalniaenaavkeklpvavfs 55 
                 ++ L ++   l++g+++i A+  + Gkt+la+ i  +a  ++  ++ v s
  EEA22450.1 449 LTLLRDVCIDLNRGEIVICAGAVGSGKTMLAMAILGEAHLTTG-TIRVSS 497
                 566677778899**********************988775333.344444 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.066
                  SBXTTXEEEEEEXTTSSHHHHHHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      DnaB_C   15 GlqkgdliiiAarpsmGktalalniaenaav 45  
                   +++g+ +i+ +r + Gk++l+l++ +   +
  EEA22450.1 1050 SINPGQKLIVVGRTGSGKSTLMLTLLQLLNT 1080
                  678899999**************99886554 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.0     0.031        14      31      58 ..     460     487 ..     436     505 .. 0.77
   2 !   10.4   0.1   0.00075      0.33      28      60 ..    1049    1081 ..    1043    1087 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.031
       AAA_7  31 knkkpvllvGptGtGKtviikdllkkld 58 
                 +++  v++ G +G+GKt++++ +l + +
  EEA22450.1 460 NRGEIVICAGAVGSGKTMLAMAILGEAH 487
                 5667899************999886655 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00075
       AAA_7   28 lllknkkpvllvGptGtGKtviikdllkkldke 60  
                  l ++ ++++++vG tG+GK++++ +ll+ l+++
  EEA22450.1 1049 LSINPGQKLIVVGRTGSGKSTLMLTLLQLLNTR 1081
                  56778899*****************99998865 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.2     0.033        15       3      23 ..     465     485 ..     463     497 .. 0.81
   2 !   10.5   0.0   0.00077      0.34       3      41 ..    1057    1095 ..    1055    1109 .. 0.79

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.033
                 EEEEESTTCCHHHHHHHHHCT CS
        cobW   3 tvltGflGsGKTtLlnhllen 23 
                 ++ +G +GsGKT+L  ++l +
  EEA22450.1 465 VICAGAVGSGKTMLAMAILGE 485
                 6789**********9988843 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00077
                  EEEEESTTCCHHHHHHHHHCT--SS-EEEEESS-SSCHC CS
        cobW    3 tvltGflGsGKTtLlnhllenraglklavivNefgevsi 41  
                  ++++G  GsGK+tL+ +ll+  + ++  + + ++  ++i
  EEA22450.1 1057 LIVVGRTGSGKSTLMLTLLQLLNTRQGSIWIDDVDITQI 1095
                  689****************88888887777777766665 PP

>> FtsK_SpoIIIE  FtsK/SpoIIIE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.1      0.17        78      33      60 ..     457     483 ..     453     495 .. 0.80
   2 !   13.2   0.2   9.5e-05     0.043      40      61 ..    1055    1076 ..    1038    1082 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.17
                   EEGGGS-.SEEEE--TTSSHHHHHHHHH CS
  FtsK_SpoIIIE  33 ldlkkmashllvaGatgsGKStalntLi 60 
                   +dl+  +  ++ aGa gsGK+   ++++
    EEA22450.1 457 IDLNRGE-IVICAGAVGSGKTMLAMAIL 483
                   6666666.67889********9988876 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 9.5e-05
                    .SEEEE--TTSSHHHHHHHHHH CS
  FtsK_SpoIIIE   40 shllvaGatgsGKStalntLil 61  
                    + l+v+G+tgsGKSt + tL++
    EEA22450.1 1055 QKLIVVGRTGSGKSTLMLTLLQ 1076
                    479***************9987 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.4   0.3    0.0086       3.9       2      21 ..     464     483 ..     463     491 .. 0.86
   2 !   10.8   0.0   0.00077      0.35       3      28 ..    1057    1082 ..    1055    1101 .. 0.93

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0086
                 CEEEEC-TTTCHHHHHHHHH CS
       NACHT   2 lvilqGeaGsGKTtLlqkla 21 
                 +vi  G+ GsGKT+L+  + 
  EEA22450.1 464 IVICAGAVGSGKTMLAMAIL 483
                 58889***********9986 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00077
                  EEEEC-TTTCHHHHHHHHHHHHCTS- CS
       NACHT    3 vilqGeaGsGKTtLlqklalawaegk 28  
                  +i+ G+ GsGK+tL+  l +++ +++
  EEA22450.1 1057 LIVVGRTGSGKSTLMLTLLQLLNTRQ 1082
                  799****************9998876 PP

>> CbiA  CobQ/CobB/MinD/ParA nucleotide binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.2      0.41   1.8e+02       1      19 [.     464     482 ..     464     487 .. 0.89
   2 ?    0.4   0.0       1.4   6.3e+02      74     110 ..     800     834 ..     569     844 .. 0.67
   3 !   10.9   0.0   0.00078      0.35       3      38 ..    1058    1093 ..    1056    1241 .. 0.63

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.41
                 EEEEESSTTSSHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxx RF
        CbiA   1 iaiastkGGvGKTtlaanL 19 
                 i+i+++  G+GKT+la ++
  EEA22450.1 464 IVICAGAVGSGKTMLAMAI 482
                 7999***********9876 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 1.4
                 ..EEEEEEEEESS...-TTCHHHHHHHHHHCTS-EEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        CbiA  74 lkiagvvlnrvdgeneetllkealeelkqrygvpvlg 110
                  + +g +lnr++ +  ++l  ++l   ++ +++++++
  EEA22450.1 800 QTDVGAILNRFGQD--INLVDKQLPPALANLNNQIFK 834
                 67789999999999..888888776666666666666 PP

  == domain 3  score: 10.9 bits;  conditional E-value: 0.00078
                  EEESSTTSSHHHHHHHHHHHHHHTT--EEEEEEEES CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        CbiA    3 iastkGGvGKTtlaanLaralarrglrVllvDaDpq 38  
                  i+ +  G+GK+tl ++L+++l+ r+  +   D+D  
  EEA22450.1 1058 IVVGRTGSGKSTLMLTLLQLLNTRQGSIWIDDVDIT 1093
                  778899*****************8888887778853 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.0     0.014       6.4      13      36 ..     461     484 ..     450     629 .. 0.91
   2 !    7.9   0.0    0.0054       2.4      11      39 ..    1051    1078 ..    1037    1110 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.014
                 TTCEEEEEESTTSSHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  13 gggdvlvaaeTGsGKTlaflipvl 36 
                 +g+ v++a+++GsGKT+ ++  + 
  EEA22450.1 461 RGEIVICAGAVGSGKTMLAMAILG 484
                 678899***********9987665 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0054
                  HHTTCEEEEEESTTSSHHHHHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   11 ilgggdvlvaaeTGsGKTlaflipvlqiv 39  
                  i  g++++v ++TGsGK++  ++ +lq +
  EEA22450.1 1051 INPGQKLIVVGRTGSGKSTL-MLTLLQLL 1078
                  457899************98.66666665 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.6   0.0    0.0043       1.9       1      32 [.     464     499 ..     464     589 .. 0.82
   2 ?    6.6   0.0     0.018       7.9       3      21 ..    1058    1076 ..    1057    1088 .. 0.87

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0043
      AAA_33   1 lvllvGlpGsGKstlaerllkklg....avllssdt 32 
                 +v++ G+ GsGK+ la  +l + +    ++++ss +
  EEA22450.1 464 IVICAGAVGSGKTMLAMAILGEAHlttgTIRVSSKE 499
                 5899**************988777777788888766 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.018
      AAA_33    3 llvGlpGsGKstlaerllk 21  
                  ++vG  GsGKstl   ll+
  EEA22450.1 1058 IVVGRTGSGKSTLMLTLLQ 1076
                  89***********998886 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.3   0.0    0.0057       2.5      16      50 ..     462     496 ..     451     500 .. 0.83
   2 !    6.7   0.0    0.0086       3.9      19      50 ..    1057    1088 ..    1052    1095 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0057
  Zeta_toxin  16 PklillgGqpGAGKselaellkdelerqgnvvrld 50 
                   +++ +G+ G+GK+ la ++  e + + + +r++
  EEA22450.1 462 GEIVICAGAVGSGKTMLAMAILGEAHLTTGTIRVS 496
                 56899****************99988777777765 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0086
  Zeta_toxin   19 illgGqpGAGKselaellkdelerqgnvvrld 50  
                  ++++G +G+GKs+l+  l + l+++++ + +d
  EEA22450.1 1057 LIVVGRTGSGKSTLMLTLLQLLNTRQGSIWID 1088
                  5899*************999999888888777 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.1   0.1    0.0018      0.83       2      35 ..     466     501 ..     465     640 .. 0.84
   2 ?    2.1   0.0      0.53   2.4e+02       2      25 ..    1058    1081 ..    1057    1142 .. 0.75
   3 ?    1.1   0.1       1.1     5e+02      52     114 ..    1196    1246 ..    1185    1260 .. 0.68

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.0018
                 EEESSTTSSHHHHHHHHHHHHT..HEEEEEETTTCS CS
         AAA   2 llyGppGtGKTllakavakelg..vefleisgsell 35 
                 +  G  G GKT+la a+  e++  +  +++s +e+ 
  EEA22450.1 466 ICAGAVGSGKTMLAMAILGEAHltTGTIRVSSKEIA 501
                 668999**************9722445777776665 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.53
                  EEESSTTSSHHHHHHHHHHHHTHE CS
         AAA    2 llyGppGtGKTllakavakelgve 25  
                  +++G  G GK++l+  + + l+++
  EEA22450.1 1058 IVVGRTGSGKSTLMLTLLQLLNTR 1081
                  789***********9999988643 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 1.1
                  HHHHTS.TSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTSSSTEEEEEEESSGGG CS
         AAA   52 eakeka.kpsilfiDEidalaksrsgseseeeervvnqLlteldgvkkkeskvivigatnrpdk 114 
                  ++k++a ++ i+++DE+ +    +          + + L+  l +  ++ +  +v+++++r + 
  EEA22450.1 1196 RVKSNAlTKPIIILDEASSSLDPE----------TESILVDLLRDDLRD-H--TVVIIAHRLEG 1246
                  5677778889******99987777..........566666666666553.3..45555555555 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.0     0.024        11      21      48 ..     454     486 ..     419     494 .. 0.73
   2 !    8.5   0.0    0.0042       1.9      11      51 ..    1043    1081 ..    1031    1087 .. 0.83

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.024
                 .......TTSEEEEEESTTSTHHHHHHHHHHHH CS
      ResIII  21 s.....krdkrglikmaTGtGKTlvaaklierl 48 
                 +     +r + ++ + a G+GKT++a+++  + 
  EEA22450.1 454 DvcidlNRGEIVICAGAVGSGKTMLAMAILGEA 486
                 0555556777788899**********9987665 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0042
                  HHHHHT......TTSEEEEEESTTSTHHHHHHHHHHHH-S. CS
      ResIII   11 aienlleklkskrdkrglikmaTGtGKTlvaaklierllkk 51  
                  a++n+  ++  +  ++++++  TG+GK+ +++ l + l + 
  EEA22450.1 1043 ALRNVSLSI--NPGQKLIVVGRTGSGKSTLMLTLLQLLNTR 1081
                  677776666..688999***************999988765 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   2.9e-05     0.013      26      56 ..    1057    1086 ..    1045    1091 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 2.9e-05
       DUF87   26 lAilgsTGsGKSntvavLleellekkgatil 56  
                  l ++g+TGsGKS+++  Ll+ l  +++++i 
  EEA22450.1 1057 LIVVGRTGSGKSTLMLTLLQLLN-TRQGSIW 1086
                  669*****************999.7777765 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.1     0.028        13      25      42 ..     465     482 ..     457     494 .. 0.88
   2 !    7.3   0.0    0.0061       2.7      13      50 ..    1045    1082 ..    1037    1110 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.028
  Mg_chelatase  25 lllvGppGsGKtmlakrl 42 
                   ++ +G+ GsGKtmla ++
    EEA22450.1 465 VICAGAVGSGKTMLAMAI 482
                   6789***********876 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0061
  Mg_chelatase   13 raleiaaaGgHnlllvGppGsGKtmlakrlpsllppls 50  
                    r + +++  g +l++vG  GsGK+ l   l +ll   +
    EEA22450.1 1045 RNVSLSINPGQKLIVVGRTGSGKSTLMLTLLQLLNTRQ 1082
                    667778888899*****************999998765 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.0      0.55   2.5e+02       2      34 ..     465     498 ..     464     619 .. 0.67
   2 ?   11.3   0.0   0.00062      0.28       2      33 ..    1057    1099 ..    1056    1115 .. 0.69

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.55
                 EEEEESTTSSHHHHHHHHHTS.TEEESSSTTSSS CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltge.kaivsdkpgtTr 34 
                 v+++G   +GK+ L  a++ge +  ++ +    +
  EEA22450.1 465 VICAGAVGSGKTMLAMAILGEaHLTTGTIRVSSK 498
                 6789***************973333333333333 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00062
                  EEEEESTTSSHHHHHHHHHT...........STEEESSSTTSS CS
    MMR_HSR1    2 vaivGrpNvGKStLinaltg...........ekaivsdkpgtT 33  
                   ++vGr+ +GKStL+ +l++           + + ++++p  T
  EEA22450.1 1057 LIVVGRTGSGKSTLMLTLLQllntrqgsiwiDDVDITQIPLRT 1099
                  689*************999655444444333355555555555 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.0      0.17        75      11      39 ..     453     482 ..     447     491 .. 0.87
   2 ?    8.7   0.0    0.0051       2.3      15      36 ..    1051    1071 ..    1039    1082 .. 0.79

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.17
      AAA_23  11 rdqeidFskgltlIt.GpNGaGKTTildAi 39 
                 rd+ id+++g  +I+ G  G+GKT +  Ai
  EEA22450.1 453 RDVCIDLNRGEIVICaGAVGSGKTMLAMAI 482
                 66679**99988887699********9998 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.0051
      AAA_23   15 idFskgltlItGpNGaGKTTil 36  
                  i+ +++l +++G +G+GK+T++
  EEA22450.1 1051 INPGQKL-IVVGRTGSGKSTLM 1071
                  5556666.789*********98 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   0.0     0.013       5.7      45      70 ..     460     486 ..     439     500 .. 0.81
   2 ?    4.5   0.0     0.056        25      44      67 ..    1051    1074 ..    1026    1093 .. 0.80
   3 ?   -1.9   0.1       5.4   2.4e+03     108     146 ..    1203    1240 ..    1192    1245 .. 0.74

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.013
   IstB_IS21  45 ekkenivllGpsGvGKshlaial.gve 70 
                 ++ e ++  G  G GK+ la+a+ g +
  EEA22450.1 460 NRGEIVICAGAVGSGKTMLAMAIlGEA 486
                 567888999*************72444 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.056
   IstB_IS21   44 iekkenivllGpsGvGKshlaial 67  
                  i+  + ++++G +G GKs l  +l
  EEA22450.1 1051 INPGQKLIVVGRTGSGKSTLMLTL 1074
                  677899************998776 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 5.4
   IstB_IS21  108 kvdllilDdlgllpldqaeaellfeviekryerrsiiit 146 
                     ++ilD+ +   ld + ++ l +++ +    ++++i 
  EEA22450.1 1203 TKPIIILDEAS-SSLDPETESILVDLLRDDLRDHTVVII 1240
                  44689999965.789*********999887766666654 PP

>> PhoH  PhoH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   0.1    0.0017      0.74      16      39 ..     459     482 ..     453     494 .. 0.86
   2 ?    1.2   0.0      0.48   2.2e+02      21      38 ..    1056    1073 ..    1043    1083 .. 0.80
   3 ?   -2.4   0.0       5.8   2.6e+03     117     131 ..    1201    1215 ..    1195    1227 .. 0.75

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0017
                 HHH-SEEEEE--TTSSTTHHHHHH CS
        PhoH  16 lkkndivfaiGpaGtGKtylaval 39 
                 l++ +iv+++G  G+GKt+la+a+
  EEA22450.1 459 LNRGEIVICAGAVGSGKTMLAMAI 482
                 66789****************985 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.48
                  EEEEE--TTSSTTHHHHH CS
        PhoH   21 ivfaiGpaGtGKtylava 38  
                   ++++G++G+GK+ l ++
  EEA22450.1 1056 KLIVVGRTGSGKSTLMLT 1073
                  56899*******998765 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 5.8
                  -B-SEEEEE-SGGG- CS
        PhoH  117 TlndafvilDEAQnt 131 
                   l + ++ilDEA + 
  EEA22450.1 1201 ALTKPIIILDEASSS 1215
                  578889*****9765 PP

>> TrwB_AAD_bind  Type IV secretion-system coupling protein DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.2      0.32   1.4e+02      19      39 ..     466     486 ..     458     495 .. 0.84
   2 ?   10.0   0.1   0.00063      0.28      16      50 ..    1055    1089 ..    1041    1095 .. 0.84

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.32
  TrwB_AAD_bind  19 livGttGsGKtqalekllrai 39 
                    + +G++GsGKt  + ++l ++
     EEA22450.1 466 ICAGAVGSGKTMLAMAILGEA 486
                    568********9999888665 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00063
  TrwB_AAD_bind   16 qhilivGttGsGKtqalekllrairargdraivlD 50  
                     q++++vG tGsGK++ +  ll+ ++ r+  + + D
     EEA22450.1 1055 QKLIVVGRTGSGKSTLMLTLLQLLNTRQGSIWIDD 1089
                     56889**********************98877766 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.1     0.009         4      16      46 ..     461     489 ..     443     499 .. 0.74
   2 ?    3.7   0.0      0.13        57      18      45 ..    1050    1080 ..    1031    1085 .. 0.74

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.009
                 HCHTEEEEEEESTTSSHHHHHHHHHHHTT-- CS
        TsaE  16 kalgdvilLeGdLGaGKTtlvrglakalgve 46 
                 +  g++++  G +G+GKT+l+ +++ + +++
  EEA22450.1 461 R--GEIVICAGAVGSGKTMLAMAILGEAHLT 489
                 2..788999************9999877654 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.13
                  H...TEEEEEEESTTSSHHHHHHHHHHHTT- CS
        TsaE   18 l...gdvilLeGdLGaGKTtlvrglakalgv 45  
                      g+ ++  G  G+GK+tl+  l++ l+ 
  EEA22450.1 1050 SinpGQKLIVVGRTGSGKSTLMLTLLQLLNT 1080
                  13446679999***********999998865 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.1      0.29   1.3e+02      19      45 ..     463     490 ..     455     503 .. 0.74
   2 ?    8.2   0.0    0.0041       1.8      20      48 ..    1056    1084 ..    1047    1090 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.29
      AAA_30  19 rvavltGpAGtGKttalkal.reaweaa 45 
                  +++  G+ G+GKt++  a+  ea+ + 
  EEA22450.1 463 EIVICAGAVGSGKTMLAMAIlGEAHLTT 490
                 589999********97555436666555 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.0041
      AAA_30   20 vavltGpAGtGKttalkalreaweaaggr 48  
                    +++G+ G+GK+t++ +l +++++++g+
  EEA22450.1 1056 KLIVVGRTGSGKSTLMLTLLQLLNTRQGS 1084
                  5799************9999998887555 PP

>> DUF2474  Protein of unknown function (DUF2474)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.1   0.00012     0.055       5      34 ..     333     362 ..     331     366 .. 0.93

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 0.00012
     DUF2474   5 kRlgWLvlIWaaSVlaLgvvAlllRllMta 34 
                 kRl W ++ + aS  aLg+ A +l l++ a
  EEA22450.1 333 KRLRWILVTYNASANALGIFAPVLTLILYA 362
                 9***********************999877 PP

>> DUF2075  Uncharacterized conserved protein (DUF2075)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.1     0.021       9.6       3      25 ..     464     486 ..     462     507 .. 0.81
   2 ?    5.0   0.0     0.026        12       4      25 ..    1057    1078 ..    1055    1088 .. 0.84

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.021
     DUF2075   3 vvlVtGvaGtGKtvvllnllael 25 
                 +v+  G+ G+GKt++++++l e+
  EEA22450.1 464 IVICAGAVGSGKTMLAMAILGEA 486
                 78999***************998 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.026
     DUF2075    4 vlVtGvaGtGKtvvllnllael 25  
                  ++V G++G+GK+ ++l+ll  l
  EEA22450.1 1057 LIVVGRTGSGKSTLMLTLLQLL 1078
                  6899*************99866 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.1      0.22        97       3      20 ..     466     483 ..     464     494 .. 0.86
   2 ?    9.3   0.2    0.0025       1.1       2      25 ..    1057    1080 ..    1056    1087 .. 0.89

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.22
                 EEE--SSSSHHHHHHHGG CS
       AAA_5   3 lLvGppGtgKselaerla 20 
                 +  G+ G+gK++la+ ++
  EEA22450.1 466 ICAGAVGSGKTMLAMAIL 483
                 6679**********9875 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.0025
                  EEEE--SSSSHHHHHHHGGGGBS- CS
       AAA_5    2 vlLvGppGtgKselaerlaaalnr 25  
                  +++vG +G+gKs+l+  l+++ln+
  EEA22450.1 1057 LIVVGRTGSGKSTLMLTLLQLLNT 1080
                  899*******************65 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0       1.9   8.6e+02      18      41 ..     460     483 ..     454     493 .. 0.82
   2 ?    6.9   0.0     0.011       5.1      19      56 ..    1053    1089 ..    1043    1099 .. 0.77
   3 ?    0.1   0.0       1.4   6.2e+02     111     131 ..    1195    1216 ..    1180    1237 .. 0.68

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 1.9
    ATPase_2  18 epneiyfiYGpegsGKtaLlkeii 41 
                 ++ ei+   G  gsGKt L + i+
  EEA22450.1 460 NRGEIVICAGAVGSGKTMLAMAIL 483
                 667888999**********98876 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.011
    ATPase_2   19 pneiyfiYGpegsGKtaLlkeiienledkdkyviyyia 56  
                  p + + + G+ gsGK++L+  +++ l+   +  i++++
  EEA22450.1 1053 PGQKLIVVGRTGSGKSTLMLTLLQLLNT-RQGSIWIDD 1089
                  55556788*************9999855.445666665 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 1.4
    ATPase_2  111 ekikkk.gkkiiiiiDelqkli 131 
                    +k +  +k+iii+De+    
  EEA22450.1 1195 LRVKSNaLTKPIIILDEASSSL 1216
                  4455440467*******98776 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0       0.3   1.3e+02       3      36 ..     463     503 ..     461     516 .. 0.81
   2 ?    5.2   0.0     0.046        21       5      27 ..    1057    1079 ..    1054    1110 .. 0.73
   3 ?   -0.6   0.0       2.9   1.3e+03      63      90 ..    1202    1231 ..    1180    1241 .. 0.68

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.3
      AAA_14   3 kilvitGaRrvGKTtllkqlikell.......vkkesilyi 36 
                 +i++  Ga  +GKT+l+  ++ e         v++++i y 
  EEA22450.1 463 EIVICAGAVGSGKTMLAMAILGEAHlttgtirVSSKEIAYC 503
                 789999**********9999877665677777667777665 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.046
      AAA_14    5 lvitGaRrvGKTtllkqlikell 27  
                  l+++G   +GK+tl+ +l++ l 
  EEA22450.1 1057 LIVVGRTGSGKSTLMLTLLQLLN 1079
                  7899999**********996655 PP

  == domain 3  score: -0.6 bits;  conditional E-value: 2.9
      AAA_14   63 ekktylflDEiqev..pewekalkslvdeg 90  
                    k +++lDE++ +  pe e++l +l++++
  EEA22450.1 1202 LTKPIIILDEASSSldPETESILVDLLRDD 1231
                  46789*****99876677888887777766 PP

>> Septin  Septin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       2.2     1e+03       7      35 ..     465     493 ..     463     511 .. 0.78
   2 ?    9.2   0.0    0.0015      0.68       6      31 ..    1056    1081 ..    1054    1103 .. 0.85

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 2.2
                 EEEEEBTTSSCCCCCCTTSSSS------- CS
      Septin   7 lmvvGesglGkttlintlfetdlieeekl 35 
                 ++++G+ g Gkt l  +++ +   ++ ++
  EEA22450.1 465 VICAGAVGSGKTMLAMAILGEAHLTTGTI 493
                 789**********9988887766665444 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.0015
                  EEEEEEBTTSSCCCCCCTTSSSS--- CS
      Septin    6 tlmvvGesglGkttlintlfetdlie 31  
                   l+vvG+ g Gk+tl+ tl++   ++
  EEA22450.1 1056 KLIVVGRTGSGKSTLMLTLLQLLNTR 1081
                  589****************9865555 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.1      0.12        52      22      45 ..     464     487 ..     455     495 .. 0.82
   2 ?    5.7   0.1     0.016       7.3      23      40 ..    1057    1074 ..    1045    1085 .. 0.80

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.12
                 EEEEEESTTSSHHHHHHHHCCSHC CS
      NB-ARC  22 vvalvGmgGvGKttlakqilnksd 45 
                 +v   G  G+GKt la  il + +
  EEA22450.1 464 IVICAGAVGSGKTMLAMAILGEAH 487
                 78889************9998754 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.016
                  EEEEESTTSSHHHHHHHH CS
      NB-ARC   23 valvGmgGvGKttlakqi 40  
                  + +vG+ G+GK+tl+   
  EEA22450.1 1057 LIVVGRTGSGKSTLMLTL 1074
                  679***********9765 PP

>> PduV-EutP  Ethanolamine utilisation - propanediol utilisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.1      0.11        50       3      25 ..     464     486 ..     462     501 .. 0.82
   2 ?    5.7   0.4     0.025        11       2      21 ..    1055    1074 ..    1054    1082 .. 0.86

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.11
   PduV-EutP   3 killiGkvgsGKttLtqalkgee 25 
                  ++  G+vgsGKt L+ a+ ge+
  EEA22450.1 464 IVICAGAVGSGKTMLAMAILGEA 486
                 58889***********9998765 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.025
   PduV-EutP    2 kkilliGkvgsGKttLtqal 21  
                  +k++++G++gsGK tL+ +l
  EEA22450.1 1055 QKLIVVGRTGSGKSTLMLTL 1074
                  689************98665 PP

>> MobB  Molybdopterin guanine dinucleotide synthesis protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.1      0.77   3.4e+02       2      22 ..     465     485 ..     464     501 .. 0.72
   2 ?    7.4   0.3    0.0083       3.7       2      27 ..    1057    1082 ..    1056    1087 .. 0.88

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.77
        MobB   2 lgivgksgsGKTtLleklipe 22 
                 +  +g  gsGKT+L   ++ e
  EEA22450.1 465 VICAGAVGSGKTMLAMAILGE 485
                 5567999*******9988765 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0083
        MobB    2 lgivgksgsGKTtLleklipelkarg 27  
                  l +vg+ gsGK tL+  l++ l+ r 
  EEA22450.1 1057 LIVVGRTGSGKSTLMLTLLQLLNTRQ 1082
                  5799******************9886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1286 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       647  (0.0360868); expected 358.6 (0.02)
Passed bias filter:                      486  (0.0271069); expected 358.6 (0.02)
Passed Vit filter:                       107  (0.00596798); expected 17.9 (0.001)
Passed Fwd filter:                        40  (0.00223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              40  [number of targets reported over threshold]
# CPU time: 0.98u 0.31s 00:00:01.29 Elapsed: 00:00:00.47
# Mc/sec: 8184.96
//
Query:       EEA22451.1  [L=608]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (608 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       474  (0.0264376); expected 358.6 (0.02)
Passed bias filter:                      426  (0.0237604); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.59u 0.30s 00:00:00.88 Elapsed: 00:00:00.45
# Mc/sec: 4042.25
//
Query:       EEA22452.1  [L=236]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.5e-05   24.3   0.0     0.0043   16.9   0.0    2.1  2  Glyco_transf_25  Glycosyltransferase family 25 (LPS biosynthe


Domain annotation for each model (and alignments):
>> Glyco_transf_25  Glycosyltransferase family 25 (LPS biosynthesis protein)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.0   2.4e-07    0.0043      63     103 ..       8      48 ..       2      63 .. 0.85
   2 !    5.3   0.0   0.00089        16     161     189 ..     122     151 ..      97     158 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 2.4e-07
  Glyco_transf_25  63 LtlgelGCylSHyllWekcvelnleyiiIlEDDvilseefk 103
                      ++ g+  C l H+ + +++v + +  ++++EDDv  + + k
       EEA22452.1   8 IGIGQTQCWLGHLNVLQEIVHRSFATALVFEDDVDWDVDIK 48 
                      6678899**************************97666655 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.00089
  Glyco_transf_25 161 a.fyllssevagtaGYlltpkaAkkllkal 189
                        +  +s++ ++t +Y +t+k A kl++++
       EEA22452.1 122 TrMVHVSQGPICTYAYAVTNKSAAKLVQMV 151
                      3478889999****************9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (236 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       338  (0.0188521); expected 358.6 (0.02)
Passed bias filter:                      299  (0.0166769); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 1649.94
//
Query:       EEA22453.1  [L=114]
Description: hypothetical protein PMAA_090820 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (114 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       183  (0.0102069); expected 358.6 (0.02)
Passed bias filter:                      137  (0.00764125); expected 358.6 (0.02)
Passed Vit filter:                         8  (0.000446204); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.44
# Mc/sec: 775.91
//
Query:       EEA22454.1  [L=595]
Description: carboxylesterase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.9e-86  289.1   0.0      1e-85  288.6   0.0    1.1  1  COesterase     Carboxylesterase family
  ------ inclusion threshold ------
      0.018   14.9   0.1       0.14   12.0   0.0    2.0  2  Abhydrolase_3  alpha/beta hydrolase fold
       0.18   11.2   0.1        0.3   10.5   0.1    1.3  1  Peptidase_S9   Prolyl oligopeptidase family


Domain annotation for each model (and alignments):
>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  288.6   0.0   1.7e-89     1e-85       5     488 ..      46     559 ..      43     579 .. 0.87

  Alignments for each domain:
  == domain 1  score: 288.6 bits;  conditional E-value: 1.7e-89
                 EEETTEEEEEEEEEESTCSEEEEEEEEESSB---GGGTTS--BE.----SSEEECBS---BESEECSSSSSCGHHCHHHBES---EEEEEEESSSSSTT CS
  COesterase   5 vetslGkvrGkrvklksekevdaFlGiPYAepPvgelRFkkPep.aepwtgvrdAtkfspaCpqnaeksekeekeleawvsEDCLyLnvytPkekkeak 102
                  +t++G+  G r+++      d FlG++YA pP+g+lRF+ P p + +wtg  +A++++p C++  +  +k        +sEDCL++nv  P+    + 
  EEA22454.1  46 ASTRNGTYTGLRNEHFA---QDFFLGMRYALPPTGDLRFNVPHPlNVSWTGSKNAQSYGPHCLSYGSDRSKFR------QSEDCLTINVVRPHI--GSP 133
                 56888888888888775...59**********************99********************8777666......8************85..578 PP

                 SSEEEEEEE--STTTS-BGCG..S-THHHHHHH.....TSEEEEE----HHHHH-B-SS..TTSBS-HHHHHHHHHHHHHHHHGGGGTEEEEEEEEEEE CS
  COesterase 103 kklPVlVwihGggfqtgsase..ydgsaLaaeg.....nvivVtinYRlGvlGFlstgd..eeapGNvGllDqvlALrWVkenIasFGGdpervtlfGe 192
                   lPV V+++Ggg + g +s+  y+ s+++++        i V++nYR  ++GF+s ++     + N+Gl Dq+lAL+W++enI++FGG+p++vt++G 
  EEA22454.1 134 GLLPVGVYFYGGGNTGGGSSDprYNLSFIVSKAtamnkPFIAVSFNYRSSIWGFISGNQvsGTGNTNLGLRDQRLALHWIQENIEAFGGNPSKVTIWGG 232
                 888************99999999*******9998898899*****************77224555579******************************* PP

                 THHHHHHHHHHHSGGGT..TSBSEEEEES--TTSTTTSBSH.HHHHHHHHHHHTTS-CSSHHHHHHHHHCS-HHHHHHCCGG.SSSSSSTTC-SSS-B- CS
  COesterase 193 sAGaasvsllllsplsr..glfkraIlqSGsalspwaiqkk.arkrakklakkvgckassskelveclrsksaeelldaqek.aleasssklvsfaPvv 287
                 s+Ga+sv ++l+    r  +lf+ aI+qSGs+l ++a+    a++  ++l + +gc  s+++++++clr  + ++l    e+ + + + +      P+ 
  EEA22454.1 233 SSGASSVGVHLIAFGGRddNLFRAAIMQSGSPLVETALPGFaAQNAYRELTQLTGC--SQTEDTLQCLRDVPPDDLDFIVESlSEDNPLILDALSLPTL 329
                 *************7766568********************9899999*********..89999************999998855677778888999*** PP

                 -SSSSSS-HHHHHHCGC..CSEEEEEEETTTTHHHHCCHSTTTSSSSHHHHHHHHHHHHHHHHHHHCC.......HHHHHHHHHHHHS........TTT CS
  COesterase 288 dgdflpekPeellkseg..kvplliGvnkdegllflaylldkeksvkkkeeklsesllkdelyleaek.......keelseaikeeyt........dea 369
                 dgd++++ P+ ll+ ++   vp++iG++++eg+ f+  +l+  ++++++  +   ++ + +l   ae        ++ + +++++ y          + 
  EEA22454.1 330 DGDIIKAFPSLLLQAAAfvRVPIIIGTTTNEGSSFVPGDLEGPENLERYLAREFITIPQPTLKWFAEVikgawllPNVVVQNLLSLYPppqsdiksLDF 428
                 ***************88*************************988888877776666555544333336689999999999999999888776644444 PP

                 SSTCHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHTT-SEEEEEEE--STTSSS..TTTGSSBTTTTHHHHTTGGGTSGCS.....S-HH.HHHHHHHHH CS
  COesterase 370 drddaeksrkallelltdvlfkapvlrtaklhasrgspvYlYsfdyrnssskk..pkwmgvvhgdeleyvfglpllekee.....ftke.deklsrkmm 460
                  +  ++++  + +ell+d +++a+ + t +   s++++++ ++fd  +s       +  gv+hg e+  vf++     ++     ++++   k+s+ m 
  EEA22454.1 429 AEGLDNAIFFQAAELLGDLVLIASHRLTCETF-SKHAKCFSFRFDALASGGDTvlGAASGVTHGAEIGPVFQNTDGFGFKrnpflNQSQcYFKMSELMG 526
                 45556677778899******************.*************998877777699*************9976666666687655666789****** PP

                 HHHHHHHHHSSTTS.....TTSS----B.TTTB CS
  COesterase 461 tywtnFaktgnPnk.....eeeekWpkytkeee 488
                 ++w nF++  nPn+       +  Wp+y+ ++ 
  EEA22454.1 527 EMWINFITDMNPNGssersIDDIIWPAYDLQSP 559
                 **************9888878889999966555 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.0     0.092   5.5e+02       2      38 ..     140     181 ..     139     183 .. 0.62
   2 ?   12.0   0.0   2.3e-05      0.14      50     103 ..     204     257 ..     199     307 .. 0.77

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.092
                    EEE--STTTS--TTTT....HHHH.HHHHHHHTSEEEEEE-- CS
  Abhydrolase_3   2 vyfHGGGfvlgsldth....dalc.relakelgavvvsvdYr 38 
                    vyf GGG + g+++ +      ++ +  a +   ++vs +Yr
     EEA22454.1 140 VYFYGGGNTGGGSSDPrynlSFIVsKATAMNKPFIAVSFNYR 181
                    8********999888744432222123333445677888887 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 2.3e-05
                    HHHHHHHHHHHHTHHHHTETTCEEEEEEETHHHHHHHHHHHHHHHTT---EEEE CS
  Abhydrolase_3  50 edalaalrwlaeqawelgadpsrivlaGdSaGGnlaaavalrardegepkvagq 103
                     d   al+w++e+ +++g +ps++++ G S G+  + + ++++  ++ +  ++ 
     EEA22454.1 204 RDQRLALHWIQENIEAFGGNPSKVTIWGGSSGASSVGVHLIAFGGRDDNLFRAA 257
                    577779*******99*****************9877666666666554444444 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.1   5.1e-05       0.3      36      97 ..     197     262 ..     164     272 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 5.1e-05
                   TSGGGGHHHHHHHHHHHHHHHHTTS--GGGEEEEEETHHHHHHHHHH...H.H-GGG-SEEEEESE CS
  Peptidase_S9  36 gkrklgqnefdDfiaaaealakegyvdserlaitGgSyGGyltgaal...n.qrpdlFkaavaevp 97 
                   g+ +lg ++ +  + ++++ ++ +  +++++ i+GgS G   +g+ l   + + ++lF+aa+ + +
    EEA22454.1 197 GNTNLGLRDQRLALHWIQENIEAFGGNPSKVTIWGGSSGASSVGVHLiafGgRDDNLFRAAIMQSG 262
                   555555555555667778888888899************99998755222348899******9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (595 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       289  (0.0161191); expected 358.6 (0.02)
Passed bias filter:                      272  (0.015171); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.59u 0.27s 00:00:00.86 Elapsed: 00:00:00.45
# Mc/sec: 3999.87
//
Query:       EEA22455.1  [L=871]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      2e-24   85.8   0.2    8.1e-23   80.7   0.2    2.6  2  MULE        MULE transposase domain
    0.00062   19.6   0.7     0.0018   18.1   0.7    1.8  1  zf-CCHC_6   Zinc knuckle
  ------ inclusion threshold ------
      0.014   15.1   1.9      0.037   13.8   1.9    1.7  1  zf-C2H2_10  C2H2 zinc-finger


Domain annotation for each model (and alignments):
>> MULE  MULE transposase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0      0.04   2.4e+02      27      58 ..      98     134 ..      94     145 .. 0.81
   2 !   80.7   0.2   1.4e-26   8.1e-23       2      95 ..     249     341 ..     248     342 .. 0.96

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.04
        MULE  27 gqlvplafalveseneesyewllq.....elleevsg 58 
                 +q  ++ f +v +e+ ++ +w+l+     +++e+++ 
  EEA22455.1  98 SQCTNCLFSVVAKESLDGTTWALRhrpdaKFCEHNHP 134
                 68899******************99887777766654 PP

  == domain 2  score: 80.7 bits;  conditional E-value: 1.4e-26
        MULE   2 vvlDgTyktnkyklplltvvgvddngqlvplafalveseneesyewllqelleevsgqrspkviitDkekallnaleevfpeakhrlClfHiak 95 
                 + lD Tyktnky lpll ++gvd++++++ +afa+++se ee+y w+l++l++   ++  p+vi+tD++ a +na+ + f  ++ +lCl+H +k
  EEA22455.1 249 LILDCTYKTNKYGLPLLDMIGVDCCQRSFCIAFAFLSSEVEEQYIWALTQLKS-LYQDALPSVILTDRCVAAMNAVDKSFTMSRSLLCLWHANK 341
                 689*************************************************9.5666*********************************998 PP

>> zf-CCHC_6  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.7     3e-07    0.0018       4      26 ..     615     637 ..     613     651 .. 0.83

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 3e-07
   zf-CCHC_6   4 CknCGAFGHtarSkrCPmkcwng 26 
                 C  C  +GH ++S  CP+k+ + 
  EEA22455.1 615 CSRCHQIGHSRKSLCCPLKHSDL 637
                 99*****************9764 PP

>> zf-C2H2_10  C2H2 zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   1.9   6.2e-06     0.037       5      16 ..     614     625 ..     610     627 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 6.2e-06
  zf-C2H2_10   5 tCSYChetGHtR 16 
                 tCS Ch++GH+R
  EEA22455.1 614 TCSRCHQIGHSR 625
                 9**********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (871 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       516  (0.0287802); expected 358.6 (0.02)
Passed bias filter:                      391  (0.0218082); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.64u 0.27s 00:00:00.91 Elapsed: 00:00:00.42
# Mc/sec: 6186.91
//
Query:       EEA22456.1  [L=255]
Description: serine-threonine protein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.6e-17   61.6   0.0    1.6e-16   60.4   0.0    1.5  1  Pkinase_Tyr  Protein tyrosine kinase
    2.8e-13   49.8   0.0    5.6e-13   48.8   0.0    1.5  1  Pkinase      Protein kinase domain
  ------ inclusion threshold ------
      0.095   12.3   0.0       0.17   11.4   0.0    1.4  1  RIO1         RIO1 family
       0.15   12.0   0.0       0.24   11.3   0.0    1.4  1  COX_ARM      COX Aromatic Rich Motif


Domain annotation for each model (and alignments):
>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.4   0.0   3.5e-20   1.6e-16      44     245 ..      39     229 ..      26     238 .. 0.81

  Alignments for each domain:
  == domain 1  score: 60.4 bits;  conditional E-value: 3.5e-20
                  HHHHHHHHHHHHHTS.-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHTCTTTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEETT CS
  Pkinase_Tyr  44 ekeelleeakimkkl.khpnivkllgvctkeepllivteyvkgGdLlkfLrkkekekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsenk 140
                   ++++  e++  k+l +h +i  l  v   e    iv+e  +g +L+k ++  e+ek+t+++ l++a++ ++G++y+++++++H d+ + N +l++  
   EEA22456.1  39 ARQAFDIEVSAYKRLgNHCRIAVLSRVTN-E---GIVLE--RGECLRKIIHGPESEKITIRTRLRWAQEASEGLSYIHKNRIIHADVGCHNLILDRLG 130
                  46666667777777766666654444433.2...36665..5668***************************************************** PP

                  EEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSEEEHHHHHHHHHHHHHHHHTTSSGTTTTS.HHHHHHHHH.HTTEES-BBTTSBHH... CS
  Pkinase_Tyr 141 vvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekkftsksDvWsfGvllwEiftlgespypgl.kneevlekl.kegkrlekpekcpee... 233
                  +++  Df+ +          + +   ++++W+a  s  +++ t+k+D+++fG +l+Ei + g+ py+++ +++e++e+l  +++r ++ e+ + e   
   EEA22456.1 131 HIRFIDFAGSG--------MDGKPPLVCYEWCA--SRGDSTTTEKTDIFAFGSTLFEIES-GNVPYHQFrETMEIFEALrAAEQRFAAGEYSNMEnll 217
                  *******7555........35778889*****9..578999*****************99.********9999******6677888887776655333 PP

                  HHHHHHHHT-SS CS
  Pkinase_Tyr 234 lyelmkkcweed 245
                  + ++++kcw+ +
   EEA22456.1 218 FRHVITKCWDGT 229
                  4689*****976 PP

>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.8   0.0   1.3e-16   5.6e-13      43     215 ..      41     203 ..      26     238 .. 0.77

  Alignments for each domain:
  == domain 1  score: 48.8 bits;  conditional E-value: 1.3e-16
                 HHHHHHHHHHHHHS.CTTB--EEEEEEESSEEEEEEE--TTEBHHHHHH..HHSS--HHHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTEEE CS
     Pkinase  43 kkvlrEikilkklk.hpnivrlyevfeekdelylvleyveggeladlle..rkgslseeeakkiakqilegleylHskgiiHrDlKpeNiLidekgelK 138
                 +++  E++  k+l  h +i  l +v +e     +vle  e   l ++++  ++ +++ ++  ++a++  egl+y+H+++iiH D+  +N+++d+ g+++
  EEA22456.1  41 QAFDIEVSAYKRLGnHCRIAVLSRVTNE----GIVLERGE--CLRKIIHgpESEKITIRTRLRWAQEASEGLSYIHKNRIIHADVGCHNLILDRLGHIR 133
                 5566677777777777777777666654....46777655..58999999888889999**************************************** PP

                 E-SGTTSEESSSSCSBCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHHHHHSS-STTTSSHHHHHHHHHHTHHH CS
     Pkinase 139 itDFGlakelessskltsfvgtseYlAPEvlkeneyskkvDvWslGvilyelltgkppfsgekgkekvekeldqlek 215
                  +DF  +    +        +  e++A +  +++ +++k+D+++ G +l+e+ +g+ p+++ +++ ++ + l+  e+
  EEA22456.1 134 FIDFAGSGMDGK-----PPLVCYEWCASR--GDSTTTEKTDIFAFGSTLFEIESGNVPYHQFRETMEIFEALRAAEQ 203
                 ****76654433.....358889999988..78999************************65555544444444333 PP

>> RIO1  RIO1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   3.9e-05      0.17     122     150 ..     109     138 ..      86     145 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 3.9e-05
                 HHTSTEEESS-STTSEEEETT.EEEE--GT CS
        RIO1 122 ykeaglvHaDLSeyNvlvded.kvviIDvs 150
                 +++++++HaD+   N+++d+  ++ +ID++
  EEA22456.1 109 IHKNRIIHADVGCHNLILDRLgHIRFIDFA 138
                 5789***************988******97 PP

>> COX_ARM  COX Aromatic Rich Motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   5.4e-05      0.24      26      45 ..     209     228 ..     190     229 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 5.4e-05
                 EES-B-TTHHHHHHHHTT-X CS
     COX_ARM  26 yFssVdpgLFdsIvnkymep 45 
                  +s+ ++ LF +++ k++++
  EEA22456.1 209 EYSNMENLLFRHVITKCWDG 228
                 69***************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (255 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       418  (0.0233142); expected 358.6 (0.02)
Passed bias filter:                      396  (0.0220871); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.47u 0.29s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 1698.89
//
Query:       EEA22457.1  [L=116]
Description: hypothetical protein PMAA_090860 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (116 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       319  (0.0177924); expected 358.6 (0.02)
Passed bias filter:                      240  (0.0133861); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.46
# Mc/sec: 763.24
//
Query:       EEA22458.1  [L=147]
Description: hypothetical protein PMAA_090870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (147 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       295  (0.0164538); expected 358.6 (0.02)
Passed bias filter:                      161  (0.00897987); expected 358.6 (0.02)
Passed Vit filter:                         7  (0.000390429); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 1042.81
//
Query:       EEA22459.1  [L=790]
Description: molybdopterin cofactor sulfurase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.2e-21   75.7   0.0    1.2e-11   44.3   0.0    2.5  2  Aminotran_5  Aminotransferase class-V
  ------ inclusion threshold ------
       0.12   12.3   0.0        0.5   10.4   0.0    2.0  2  zf_CopZ      Zinc binding domain


Domain annotation for each model (and alignments):
>> Aminotran_5  Aminotransferase class-V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.9   0.0     6e-11   5.4e-07       2      84 ..      20     103 ..      19     127 .. 0.85
   2 !   44.3   0.0   1.3e-15   1.2e-11     142     371 .]     176     462 ..     168     462 .. 0.77

  Alignments for each domain:
  == domain 1  score: 28.9 bits;  conditional E-value: 6e-11
                  EEBTTTS----HHHHHHHHHHH.HCTCCSSSSSSSHHHHHHHHHHHHHHHHHHHHHT-STGG.GEEEESSHHHHHHHHHHHCCCC CS
  Aminotran_5   2 yldsaAttqkpqeVldalqeyy.tdynanvhrsvhhlgkeatkaveearekvaelinaesee.eiiftsGtteainlvalslars 84 
                  yld+ + t+  ++ +d  ++ + +d  +n+h++    + +at+ v++ar +v e+++ae e+ +++f+ ++t ai+lva++++++
   EEA22459.1  20 YLDYGGATPYAKSLVDISAKLWkSDLLGNPHSNSA-SSLRATEYVNQARRQVLEFFHAEPEDfDVVFVANATAAIKLVAYCFQEK 103
                  9**************988887725799***99644.45678*****************986558*****************9654 PP

  == domain 2  score: 44.3 bits;  conditional E-value: 1.3e-15
                  EEEEESBETTTTEB--HHHHHHHHHH.T....T-EEEEE-TTTTTTS---HHHHTE..SEEEEETTTTTSSTT-EEEEEEHHHHHTS...SS.STTSE CS
  Aminotran_5 142 lvaithvsnvtGtiqpveeigklakk.k....galvlvDaaqavghipidvkklgv..DflafsghKllgPtGiGvlyvrkellekl.eplllggemv 231
                  lv + + sn+ G   p +  ++l +k +    g ++l+Daa+   ++++d+++ ++  Df+++s  K++g + +G+l+vrk+    l    ++gg++v
   EEA22459.1 176 LVGYPAQSNMNGHRTPKQWAKRLRQKsYttsgGLYTLLDAAAYCSSAQLDLSDPDAapDFISVSFYKIFGMPDLGALIVRKKSSDILtSRQYFGGGTV 273
                  55566666666666554443333222212224899*****************998777************************9999966677899999 PP

                  EEEET.TEEEEHCTTGGGS....SS--HHHHHHHHHHHHHHHCH..HHHHHHHHHHHHHHHHHHHHCTSTT......EEEES.-.....B-CTCBSEE CS
  Aminotran_5 232 eevsl.eettfaeapskfea...GTpnvagiiglgaaleyleei..gleaiekhekelaeyllerlkslpg......vrlygpd.....kaerrasiv 312
                  + v++ ++ + +++++  ea   GT +  +++ l++ + + +++   +++i kh+ +la +l+ +l++l++      +++y+ +     + + +  +v
   EEA22459.1 274 NMVTVsDYFHAKKSDHIHEAledGTLPFHNLVMLTTGIVLHRRLfhSMDKISKHASQLALQLYTGLSQLQHangrmvCKIYKDKsstygDRDTQGPTV 371
                  99999888887777765444444****************99765448*******************99987333333455552211111345666778 PP

                  EEEETTCSH....HHHHHHHHHT.TEEEEEE-TTT......HHHHHHTT.S..........................-EEEEE--TTS-HHHHHHH CS
  Aminotran_5 313 sfnfkgvha....edvatlLdee.gIavrsGhhca......qplmkrlale..........................gtvRaSlyiynteeevdrl 371
                  +f++ + +      d + +L+++ +I +r+G  c       +     l+l+                          g+vRaSl+  +++ +v+ l
   EEA22459.1 372 AFAICKADGawvhYDHVEALASAcNIQIRTGGVCNpggiaeH-----LELAtwemrrnycegyrcgepfkirggkpsGIVRASLGAMSDNRDVETL 462
                  888866666777789999999999**********97554443.....4444555559999999999***************************976 PP

>> zf_CopZ  Zinc binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0      0.43   3.8e+03       6      22 ..     375     391 ..     374     396 .. 0.87
   2 ?   10.4   0.0   5.6e-05       0.5       3      34 ..     752     783 ..     750     787 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.43
                 TT--B-EEE-HHHHHHH CS
     zf_CopZ   6 vCgkkGkkVkliTvkhl 22 
                  C++ G  V++  v++l
  EEA22459.1 375 ICKADGAWVHYDHVEAL 391
                 59*********999987 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 5.6e-05
                 B-TTT--B-EEE-HHHHHHHB-GGGGGG--S- CS
     zf_CopZ   3 kCPvCgkkGkkVkliTvkhllkpellekvkee 34 
                  CPv g  +k+V++ T  h+lk+++++ +k++
  EEA22459.1 752 FCPVTGCGAKNVDYSTFLHHLKDHARPFIKSR 783
                 7************************9987665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (790 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       452  (0.0252106); expected 358.6 (0.02)
Passed bias filter:                      428  (0.0238719); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.26s 00:00:00.93 Elapsed: 00:00:00.44
# Mc/sec: 5385.83
//
Query:       EEA22460.1  [L=307]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (307 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       398  (0.0221987); expected 358.6 (0.02)
Passed bias filter:                      282  (0.0157287); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.22s 00:00:00.65 Elapsed: 00:00:00.38
# Mc/sec: 2450.85
//
Query:       EEA22461.1  [L=280]
Description: hypothetical protein PMAA_090900 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      7e-05   22.2   0.1    0.00013   21.3   0.1    1.4  1  SKG6      Transmembrane alpha-helix domain
  ------ inclusion threshold ------
       0.18   11.7   1.3       0.43   10.4   1.3    1.6  1  Mid2      Mid2 like cell wall stress sensor


Domain annotation for each model (and alignments):
>> SKG6  Transmembrane alpha-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.1   1.4e-08   0.00013       5      37 ..     178     210 ..     176     211 .. 0.91

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 1.4e-08
        SKG6   5 snsntvaIavaVaVPVaViiivLlailifvrRR 37 
                 +++ t  ++v+V+VP++ i ++ +a  ++ rR+
  EEA22461.1 178 DHHATIGVGVGVGVPLGLITLASIAWALWERRK 210
                 599999****************99999988887 PP

>> Mid2  Mid2 like cell wall stress sensor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   1.3   4.8e-05      0.43       7      66 ..     150     199 ..     145     212 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 4.8e-05
        Mid2   7 siiegktiLsdlyttvtytptataessnkskssGLskknrniviGcvvGigvPlllvill 66 
                 si+ g ++Ls+ yttv+ + ++t ++ n          +++  iG+ vG+gvPl l++l+
  EEA22461.1 150 SIVPGYALLSE-YTTVSNAMSSTGSNPN---------GDHHATIGVGVGVGVPLGLITLA 199
                 67777787775.7888877766666644.........3556789**********888775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (280 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       506  (0.0282224); expected 358.6 (0.02)
Passed bias filter:                      283  (0.0157845); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.43u 0.24s 00:00:00.67 Elapsed: 00:00:00.41
# Mc/sec: 2069.74
//
Query:       EEA22462.1  [L=211]
Description: hypothetical protein PMAA_090910 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
     0.0016   19.2   2.6      0.002   18.9   1.9    1.5  1  GPI-anchored  Ser-Thr-rich glycosyl-phosphatidyl-inositol-anc


Domain annotation for each model (and alignments):
>> GPI-anchored  Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   1.9   1.1e-07     0.002       1      91 [.      23     117 ..      23     119 .. 0.81

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 1.1e-07
  GPI-anchored   1 tsPssgevvtagkpvtitWkdsgtdp..gtvtlvLcagss.nnlksvktiasgiknsdgsytwtv...paslesggaYflqivsesnegiynySdrF 91 
                   tsP +g++++  + + i+W  ++td    +v+++L++++  +   +  +  s+++ +d syt++    ++ ++++++Y + ++++sn+  ++ +  F
    EEA22462.1  23 TSPNAGDKIDIQQGLPISWIVEDTDNltANVDIQLYWNERfQVGLTWSEPGSTVPINDSSYTFQYtrdKDYIWPKTDYVVYLYDGSNS--THKTGEF 117
                   79*******************99998999***********433444456677888777999999965555899999*******99997..5555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (211 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       608  (0.0339115); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1547.41
//
Query:       EEA22463.1  [L=413]
Description: monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.7e-25   89.3   0.0    3.4e-18   66.0   0.0    2.9  2  FAD_binding_3  FAD binding domain
    0.00051   20.2   0.0     0.0011   19.1   0.0    1.6  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
     0.0006   20.3   0.0       0.19   12.3   0.0    2.5  2  Pyr_redox      Pyridine nucleotide-disulphide oxidoreductase
     0.0028   16.9   0.0      0.064   12.5   0.0    2.2  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
      0.017   14.2   0.0       0.11   11.6   0.0    2.1  3  Lycopene_cycl  Lycopene cyclase protein
      0.021   13.9   0.0      0.048   12.7   0.0    1.6  1  FAD_binding_2  FAD binding domain
      0.032   13.8   0.0      0.057   13.0   0.0    1.5  2  DAO            FAD dependent oxidoreductase
      0.033   12.9   0.0       0.16   10.6   0.0    1.9  2  HI0933_like    HI0933-like protein
        0.1   11.8   0.0       0.24   10.6   0.0    1.5  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
       0.13   12.5   0.0       0.27   11.5   0.0    1.5  1  TrkA_N         TrkA-N domain


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0     5e-07   0.00091       3      41 ..      13      51 ..      11      55 .. 0.91
   2 !   66.0   0.0   1.9e-21   3.4e-18     118     342 ..     128     372 ..     117     379 .. 0.71

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 5e-07
                   EEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSSS CS
  FAD_binding_3  3 dVlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlpr 41
                   +VlI+G+G +Gl+la+ L++  ++ +l e+ +++++  +
     EEA22463.1 13 KVLIIGGGTSGLVLAHGLQQENIQYILFERDAEDIYWNK 51
                   8*******************************9988665 PP

  == domain 2  score: 66.0 bits;  conditional E-value: 1.9e-21
                    HTEEETCSEEEECCEECCCC.CCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHHHTGGEEEEEEEEEEEEEEEEEEC-SCCCTTCCEEEEECCTT CS
  FAD_binding_3 118 rglqvrfktevesleqdeeg.vtaevrdketgeeetvrakYlvGaDGgrStvrktlgiefegeetvyeagvldvlfdadlsdiveplvlilsaesr 212
                    +gl++ f+++++s+++d++g vta + d + +e    +a  l+G+DG rS+vr+ l  e  ++ t++++++++  +    +  +e+  l+++ +  
     EEA22463.1 128 TGLKIMFEKKLVSIKHDQDGlVTASFSDGS-QE----TASLLIGCDGSRSKVRSFLVGEELAKPTDIDLTMMNHAAGG-YT--AEQAILLRKYHAI 215
                    799****************95677777764.34....49***************876664555555466666655444.33..2443444444444 PP

                    EE....................EEEECCE.TEEEEEEEEECCE-GGGS...CCCHHHHHHHHHHH..HHHTTSSCEEEEEEEEEEEEEEEEESSSE CS
  FAD_binding_3 213 gv....................mviPlen.tlerfyvqvearaekeer...sekfteeevkarlr..eivgektldveieevsawtvaqrvaekyr 282
                    g                        P e  ++ ++ +  + + ++ ++   + +f ++++++  +  +  g +  d ei  + + + ++ +  + r
     EEA22463.1 216 GKiayhpdyygnflltaldcsnLEKPEEWtFQIQHCWWGPPYLDELKDpktRLEFYKTRCSKMCEpfRTAGVALPDDEILPIDQSQQWAPIEWDNR 311
                    435666777777889877666533344443444444444444433222123445556666665552234556666778888888888889999*** PP

                    ETTEEE-GGGTEEE-STTSHHHHHHHHHHHHHHHHHHHHHTTSS-.GGGGHHHHHHHHHHH CS
  FAD_binding_3 283 kgrvflaGDAaHihpPtgGqGlNtaiqDavnLawkLaavlkGeAk.eelLdtYeeerrava 342
                    +g v laGDAaH + P  GqGlN a++D+ +L+ ++ +vl+G+   e+ + +Ye+  r+++
     EEA22463.1 312 RGTVTLAGDAAHSMLPHRGQGLNNALRDVAELFEAIKQVLSGQFTlEAAITSYETAMRPRG 372
                    ******************************************9653788999998888775 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   6.3e-07    0.0011       1      28 [.      16      43 ..      16      68 .. 0.95

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 6.3e-07
                   EE--SHHHHHHHHHHHCCTEEEEEE-SS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekr 28
                   I+G+G sGlv+A+ L++++++  l+e+ 
     EEA22463.1 16 IIGGGTSGLVLAHGLQQENIQYILFERD 43
                   9************************985 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.3   0.0   0.00011      0.19       1      31 [.      13      43 ..      13      64 .. 0.91
   2 ?    5.5   0.0     0.014        25      48      74 ..     118     150 ..     102     156 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00011
                EEEEECSSHHHHHHHHHHHHTTSEEEEEESS CS
   Pyr_redox  1 kvvvvGgGyiglElAgalaelgkkVtvvers 31
                kv+++GgG++gl lA  l++ + +  ++er 
  EEA22463.1 13 KVLIIGGGTSGLVLAHGLQQENIQYILFERD 43
                79*****************999999999986 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.014
                 HHHHHT.....TEEEECSEEEEEEEEETTS.EE CS
   Pyr_redox  48 eklekn.....gievllntkveeiegsedg.ve 74 
                 +kl+++     g ++++++k+++i++++dg v+
  EEA22463.1 118 RKLRRLlgwgtGLKIMFEKKLVSIKHDQDGlVT 150
                 5555555555699*****************665 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.5   0.0   3.6e-05     0.064       1      32 [.      12      43 ..      12      53 .. 0.85
   2 ?    2.1   0.0     0.051        91     197     240 ..     129     173 ..     116     188 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 3.6e-05
                 CSEEEE--SHHHHHHHHHHHHHTS-EEEEETT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  1 kdvvviGgGpAGlaaaltlaqagakvtlvele 32
                 ++v++iGgG  Gl +a+ l+q +++ +l+e++
   EEA22463.1 12 FKVLIIGGGTSGLVLAHGLQQENIQYILFERD 43
                 58***********************9999843 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.051
                  TEEEEESCEEEEEEETTE.EEEEEETTSCEEEESEEEE-S-EEES CS
                  xxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 197 Gvevklgtsvkeidgnge.klevvledgeeidadlvvvavGvrps 240
                  G +++++++ + i+ +++  ++   +dg+++ a+l++ + G r +
   EEA22463.1 129 GLKIMFEKKLVSIKHDQDgLVTASFSDGSQETASLLIGCDGSRSK 173
                  8899999**********97777***************99999876 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   5.9e-05      0.11       2      45 ..      14      56 ..      13      68 .. 0.83
   2 ?   -0.8   0.0      0.35   6.3e+02      83     143 ..     114     172 ..     104     184 .. 0.77
   3 ?   -2.7   0.0       1.3   2.4e+03     258     311 ..     315     367 ..     293     374 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 5.9e-05
  Lycopene_cycl  2 vvviGaGpAglslAarlteakpglkvvliea.spsllfpnnyvWs 45
                   v++iG+G  gl lA+ l  ++ +++ +l e  ++++ +   + W 
     EEA22463.1 14 VLIIGGGTSGLVLAHGL--QQENIQYILFERdAEDIYWNKSRDWG 56
                   89***************..99999999999724566666666885 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.35
  Lycopene_cycl  83 rvsskrlkeellerlvengvklleakvesveeeeageslvvleggrkirarlvvdarglas 143
                    rvs+++l++ l     ++  ++ e k  s++++++g +++  ++g +  a+l +   g  s
     EEA22463.1 114 RVSRRKLRRLLGWG--TGLKIMFEKKLVSIKHDQDGLVTASFSDGSQETASLLIGCDGSRS 172
                    56666666555433..3366778889999*****************999999998888433 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 1.3
  Lycopene_cycl 258 vlaiGaaaglvhPaTGYsvarslaeapllasaiaaalresslsarawatlwpre 311
                    v  +G aa  + P  G  + ++l+    l +ai ++l   +   +a+ t++  +
     EEA22463.1 315 VTLAGDAAHSMLPHRGQGLNNALRDVAELFEAIKQVLSG-QFTLEAAITSYETA 367
                    667888999999999999999999999899999999984.77777776666554 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   2.7e-05     0.048       2      31 ..      14      43 ..      13      50 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.7e-05
                   EEEE--SHHHHHHHHHHHHTTT-EEEEESS CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaeaGlkvavveke 31
                   v++iG+G +GL+ A+ +++++ + ++ e  
     EEA22463.1 14 VLIIGGGTSGLVLAHGLQQENIQYILFERD 43
                   9*********************99999876 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   3.2e-05     0.057       1      45 [.      13      60 ..      13     167 .. 0.81
   2 ?   -2.9   0.0       2.2   3.9e+03     261     296 ..     313     351 ..     276     375 .. 0.51

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 3.2e-05
                EEEEECTSHHHHHHHHHHHHTT..EEEEESS.SSTTSSGGGSSEEEEE CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..Vtllekg.diagsgaSgrnsgllh 45
                +v+iiGGG  Gl  A+ L++++   +l+e++ +++ +  S   + +lh
  EEA22463.1 13 KVLIIGGGTSGLVLAHGLQQENiqYILFERDaEDIYWNKSRDWGMQLH 60
                59****************8888999****9944455566665555555 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 2.2
                 SEEEEEESSE....EETTCSSTSCSHHHHHHHHHHHHHHS CS
         DAO 261 grvlvGgtad....eesgdddpevdeedidellealrklf 296
                 g+v + g+a     +++g +      +d++el ea+++++
  EEA22463.1 313 GTVTLAGDAAhsmlPHRGQGL-NNALRDVAELFEAIKQVL 351
                 333333322223222222222.333344444444444444 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0     9e-05      0.16       2      32 ..      13      43 ..      12      46 .. 0.92
   2 ?   -0.4   0.0       0.2   3.5e+02     123     181 ..     129     185 ..     122     213 .. 0.72

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 9e-05
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SS CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVllleka 32
                 +v++iGgG +Gl  A  +++++ + +l+e+ 
   EEA22463.1 13 KVLIIGGGTSGLVLAHGLQQENIQYILFERD 43
                 89************************99975 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.2
                  T-EEE-S--EEEEECETTE.EEEEE.TTEEEEESEEEE----SS-GGGT--SHHHHHHH CS
  HI0933_like 123 gvklrletevksvekeedgkfrvktkseeeleadklvlAtGGlSiPklGstgkgyklae 181
                  g k++ e+++ s+++++dg ++ +  s+++ e+++l++ + G S  k+ s   g +la+
   EEA22463.1 129 GLKIMFEKKLVSIKHDQDGLVTASF-SDGSQETASLLIGCDG-SRSKVRSFLVGEELAK 185
                  7899999************888888.7777788888887544.4445555555555555 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00013      0.24       1      30 [.      15      43 ..      15      48 .. 0.92
   2 ?   -3.2   0.0       2.1   3.8e+03     227     254 ..     130     158 ..     115     178 .. 0.65

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00013
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEkg 30
                 +IiG+G  Gl  a+ l++ ++ +y+  E++
   EEA22463.1 15 LIIGGGTSGLVLAHGLQQENI-QYILFERD 43
                 6********************.79999986 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.1
  Pyr_redox_3 227 ikvlfnaevkeikekeee.ykvktedgkk 254
                  +k++f++++ +ik+++   ++ +++dg++
   EEA22463.1 130 LKIMFEKKLVSIKHDQDGlVTASFSDGSQ 158
                  77888888888886655414555666655 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   0.00015      0.27       1      33 [.      14      46 ..      14      54 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00015
                EEEES-SHHHHHHHHHHHHTTEEEEEEESSHHH CS
      TrkA_N  1 iiiiGlGrvGrslaeeLseggkdvvvidkdeer 33
                ++iiG G+ G  la+ L+++++++++ ++d e 
  EEA22463.1 14 VLIIGGGTSGLVLAHGLQQENIQYILFERDAED 46
                68*****************9989******9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (413 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       471  (0.0262703); expected 358.6 (0.02)
Passed bias filter:                      459  (0.025601); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.62u 0.28s 00:00:00.90 Elapsed: 00:00:00.49
# Mc/sec: 2512.94
//
Query:       EEA22464.1  [L=381]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        0.6   10.8   4.8       0.24   12.0   1.4    2.0  2  Pex14_N   Peroxisomal membrane anchor protein (Pex14p) conser


Domain annotation for each model (and alignments):
>> Pex14_N  Peroxisomal membrane anchor protein (Pex14p) conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1      0.18   3.3e+03      32      55 ..      97     123 ..      80     156 .. 0.56
   2 ?   12.0   1.4   1.4e-05      0.24      34      95 ..     212     281 ..     211     308 .. 0.48

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.18
     Pex14_N  32 KGLtqeEIeeaLkraereeease...s 55 
                 KG+t + + + L+r++ +  a++   +
  EEA22464.1  97 KGMTAALVYRTLERNSGTVGATSalcT 123
                 777777777777775544443333321 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 1.4e-05
     Pex14_N  34 LtqeEIeeaLkraereeease.....savaassas...eqa....qeesasssatpqpqaasqtsqsspspspp 95 
                 +t +EI++aL+ a+ + +a+      +   a++++   + +    +++ +ss+a ++++ as++++s++s+ ++
  EEA22464.1 212 VTAQEIQAALASAGVKGSATGasstvP---AAAPAaapA-TtspsTDACSSSTAATSNTGASTNTASTTSTGTS 281
                 6899********998877766543331...222221221.1223322222222222222222222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (381 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       990  (0.0552178); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 2536.70
//
Query:       EEA22465.1  [L=392]
Description: 60S ribosomal protein L3 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   3.8e-183  608.6  11.6   4.3e-183  608.4  11.6    1.0  1  Ribosomal_L3  Ribosomal protein L3


Domain annotation for each model (and alignments):
>> Ribosomal_L3  Ribosomal protein L3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  608.4  11.6  2.4e-187  4.3e-183       1     369 []       1     367 [.       1     367 [. 1.00

  Alignments for each domain:
  == domain 1  score: 608.4 bits;  conditional E-value: 2.4e-187
                   XX.S.SXXXXSSXCCCTTXSBXSXSSXXXSX.XXSBTTTTTXBSEEEEEEEEEEEEEEECHHTTSCCCCCEEEEEEEEEEC--EEEEEEEEEEEETT CS
  Ribosomal_L3   1 mshrkfeaprhgslGflprkRaerergkvksfPkddtskpvkltaflGyKaGmthiVrevdkpgskldkkevveavtvvetppmvivgvvgyvetpr 97 
                   mshrk+eaprhgsl +lprkRa+r+rgkvksfPkdd +kpv+lta +GyKaGmt+iVr++d+pg+k++kkevveavtv+etpp+v+vgvvgy+etpr
    EEA22465.1   1 MSHRKYEAPRHGSLAYLPRKRAARHRGKVKSFPKDDPKKPVHLTASMGYKAGMTTIVRDLDRPGAKMHKKEVVEAVTVIETPPLVAVGVVGYIETPR 97 
                   9************************************************************************************************ PP

                   EEEEEEEEESSS.SHHHHCCCSTSTTTSSSSSSHCCCCHCSSCCCCCCHHHHHHHHHHSCSCEEEEEEEECCCSS-SCCSSHHEEEEECHCSCHHHH CS
  Ribosomal_L3  98 GlrslktvwaehlseevkrrlyknwykskkkaftkyskkyeskdvkklieadleeikkeasvvrviahtvirktkslaqKkahllEiqvngGtiaek 194
                   Glrsl+tvwaehls+e+krr+yknwykskkkaft+y+kk+ ++ + +++ ++le+ikk+++vvr++aht+irkt+ l+qKkahl+EiqvngG+ia+k
    EEA22465.1  98 GLRSLTTVWAEHLSDELKRRFYKNWYKSKKKAFTRYTKKH-TESSAASVTRELERIKKYCTVVRILAHTQIRKTP-LKQKKAHLMEIQVNGGSIADK 192
                   ***************************************9.89999*****************************.********************* PP

                   HHHHHHCCTCEEECCCCS-TTSEEEEEEEE---EEE-HHHHCT----STTTSSSSSS-S-SS-SSSSS--TTS--SEEESCCEEEEEEEEEEEEETT CS
  Ribosomal_L3 195 ldfarealektvavaavFrqgeliDvigvtkGkGfeGvvkRWgvkklprkthrglRkvaaigawdparVsstvaraGqkGyhhRtelnkkiyrigkg 291
                   ++fa+  +ekt++++ +F+q+e+iDvi+vtkG+Gf+Gv++RWg+kklprkth+glRkva+igaw+p++V++tvaraGq+GyhhRt++n+kiyrigkg
    EEA22465.1 193 VEFAHGLFEKTIDIDTIFEQNEVIDVIAVTKGHGFNGVTSRWGTKKLPRKTHKGLRKVACIGAWHPSHVQWTVARAGQMGYHHRTSVNHKIYRIGKG 289
                   ************************************************************************************************* PP

                   TSSTTTSSTTT.SS..SS.TTTCTTCB..TSCEEEEES--SSSTTEEEEEEE-SSGGGSCCCSS-EEEEEE-TTCTSS CS
  Ribosomal_L3 292 edaknastefdltekeitPmGGfvhyGevkndfilvkGsvpGpkkrlvklrkslltqtsrkaeeevslkfidtaskfg 369
                   +d+ nastefd ++k+itP+GGfv+yGevkndf++vkGsvpG kkr+++lrk+l++q srka e+++lk+idt+s+fg
    EEA22465.1 290 SDEGNASTEFDVSKKTITPLGGFVRYGEVKNDFVIVKGSVPGVKKRVMTLRKTLYPQVSRKATEKIDLKWIDTSSEFG 367
                   ****************************************************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (392 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       826  (0.0460706); expected 358.6 (0.02)
Passed bias filter:                      544  (0.0303419); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.24s 00:00:00.78 Elapsed: 00:00:00.40
# Mc/sec: 2943.80
//
Query:       EEA22466.1  [L=333]
Description: NmrA family transcriptional regulator, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.3e-59  199.9   0.3    5.5e-59  199.5   0.3    1.1  1  NmrA             NmrA-like family
    1.7e-18   67.2   0.0    2.5e-18   66.6   0.0    1.2  1  NAD_binding_10   NAD(P)H-binding
    7.7e-07   28.4   0.0    1.1e-06   27.8   0.0    1.2  1  3Beta_HSD        3-beta hydroxysteroid dehydrogenase/isomeras
     0.0002   20.9   0.0     0.0003   20.3   0.0    1.3  1  Epimerase        NAD dependent epimerase/dehydratase family
     0.0036   17.5   0.1     0.0082   16.4   0.0    1.6  2  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma
  ------ inclusion threshold ------
       0.08   13.0   0.0       0.21   11.7   0.0    1.7  2  FtsJ             FtsJ-like methyltransferase


Domain annotation for each model (and alignments):
>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  199.5   0.3   1.8e-62   5.5e-59       1     227 [.      33     265 ..      33     271 .. 0.93

  Alignments for each domain:
  == domain 1  score: 199.5 bits;  conditional E-value: 1.8e-62
                 EEESSTTSHHHHHHHHHHHH.....HT-EEEEEES-S-SHHHHHHHHSTTEEEES-TT-HHHHHHHHTT-SEEEE---GG.....S-HHHHHHHHHHHH CS
        NmrA   1 IlviGaTGrqGksvvrallk.....aghkvralvRdtkselakslkeaGvelvkgdlddkeslvealkgvdvvfsvtgfy.....skeiedgkklvdAa 89 
                 I+v+GaTG+qG+sv+r ll+     +++k+r ++Rd+++e+ak+l+++Gve++ +d+ + +sl+ealkg+++vf+vt+f+     ++e+++gk+++dA 
  EEA22466.1  33 ITVFGATGNQGGSVIRSLLAdpvlaKEYKIRGITRDVTKEAAKKLSSQGVEMITADMSSPSSLDEALKGSHTVFLVTNFWetmskDTEVAQGKAVADAC 131
                 89****************99999999**********************************************************99************* PP

                 HHHS-SEEEEEE---GG.GT.SSS---TTTHHHHHHHHHHHHCTS-EEEEEE-EEGGG-BSSS-SS-BEEE-TTS.-EEEEESS-TTS-EE...-HHHH CS
        NmrA  90 keaGvkhfiySslgddndrsnaeepavphfdsKaeieeyvralgipytfvyagffmenflsllaqlkvgdtappedkvtllgpgnpkavll...daeeD 185
                 k+ Gvkh+i+Ssl + ++ ++++ p+v+hf+ Kaeie+y+r++gip+tfv+ag+fm+ +++++ +       +  d + l  p +p+ + +   d eeD
  EEA22466.1 132 KNTGVKHLIFSSLRSISEVTSGKLPNVSHFEGKAEIEQYIRNSGIPATFVLAGLFMQGLSGSMIK-------KRDDVYMLALPIDPETAKIpvfDVEED 223
                 *************************************************************8888.......333466666666665544446899*** PP

                 HHHHHHHHHHHHHHHTTEEEEE-SEEE-HHHHHHHHHHHHTS CS
        NmrA 186 iGafvikilkdprklkgkriklagntlsgneivelfekkigk 227
                 +G+fv +++k+  ++ gkri +a++++s+ ++ + +++ +g 
  EEA22466.1 224 TGKFVKAVVKNYPNIIGKRILIATDYVSPRQLTDEISQTLGV 265
                 ********************************9999998885 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.6   0.0   8.3e-22   2.5e-18       1     150 [.      37     190 ..      37     204 .. 0.86

  Alignments for each domain:
  == domain 1  score: 66.6 bits;  conditional E-value: 8.3e-22
                     TTTSHHHHHHHHHHHHC-....T-EEEEEETT..HHHCHHHHCTTTCEEEE--TT-CCHHHHHHTT-SEEEES-.....--TCCHHHHHHHHHHH CS
  NAD_binding_10   1 GAtGkvGrllvkellarg....ghevtalvRn..peklaeleaeeglevvegdvtdvedlaealkgadaVvsal.....ggggkdeegaknivda 84 
                     GAtG+ G  +++ lla+     +++++ ++R+  +e +++l+ ++g+e++++d++++++l ealkg  +V+  +      +++++  + k+++da
      EEA22466.1  37 GATGNQGGSVIRSLLADPvlakEYKIRGITRDvtKEAAKKLS-SQGVEMITADMSSPSSLDEALKGSHTVFLVTnfwetMSKDTEVAQGKAVADA 130
                     9****************999999********96667777886.7******************************555433333344449****** PP

                     HHHCT--EEEEEEETTTTSGCGCHHHHHHHHCCHHHHHHHHHHHHHHHHSSSEEEEEEE-CEE-ST CS
  NAD_binding_10  85 akeagvkRfvlvsaigvgdevpgefgewnkellkaylaakraaeellrasgldwTivrpggLtdep 150
                     +k++gvk++++ s   + + + g+++++      + ++ k++ e+++r+sg+  T+v  g ++++ 
      EEA22466.1 131 CKNTGVKHLIFSSLRSISEVTSGKLPNV------SHFEGKAEIEQYIRNSGIPATFVLAGLFMQGL 190
                     ***********99999998888888776......45789******************999988775 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.0   3.8e-10   1.1e-06       2     116 ..      35     144 ..      34     159 .. 0.79

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 3.8e-10
   3Beta_HSD   2 vtGgaGFlGralvkeLvrlee.l..kevrvlDlrespelleelskvnvkkviegDvtdkdkleealegvdvvihlaslvdvagkltedeimkvnvkGTr 97 
                 v G++G  G +++++L+     +   ++r +  +  +e  ++ls+ +v+ +i++D+ + ++l+eal+g++ v+ +    + ++k   d      v   +
  EEA22466.1  35 VFGATGNQGGSVIRSLLADPVlAkeYKIRGITRDVTKEAAKKLSSQGVE-MITADMSSPSSLDEALKGSHTVFLVTNFWETMSK---D----TEVAQGK 125
                 899*************986554400557767666667776677777777.***********************99777777763...3....3455569 PP

   3Beta_HSD  98 nvleacvkagvrvlvYtSs 116
                  v +ac+++gv+ l++ S 
  EEA22466.1 126 AVADACKNTGVKHLIFSSL 144
                 9***************884 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0     1e-07    0.0003       1     114 [.      33     143 ..      33     171 .. 0.87

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 1e-07
                 EEEETTTSHHHHHHHHHHHHCT.....SEEEEEES-STTTTCHHCHHC..EEEE--TT-HHHHHHHHHHHT-SEEEE--S---HHHHHHSHHHHHHHHT CS
   Epimerase   1 ilVtGatGfiGsalvkallekg.....yevigldrlssasntarledl..elveldltdrsalerlfkeeqpdavihlAavggvaassedpadfieknl 92 
                 i V GatG  G  +++ ll+       y++ g++r+ ++++ ++l     e++++d+  +s+l++++k  + ++v+++     +++ s+d      + +
  EEA22466.1  33 ITVFGATGNQGGSVIRSLLADPvlakeYKIRGITRDVTKEAAKKLSSQgvEMITADMSSPSSLDEALK--GSHTVFLV--TNFWETMSKD------TEV 121
                 7899*******9999999998888888*********99999998888899******************..99999999..4445444444......667 PP

                 HHHHHHHHHHHHHTCTEEEEEE CS
   Epimerase  93 qgtlnlleaarkagvkrllfls 114
                 +    +++a++ +gvk l+f s
  EEA22466.1 122 AQGKAVADACKNTGVKHLIFSS 143
                 77999**********9999887 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0   2.8e-06    0.0082       1      95 [.      33     137 ..      33     155 .. 0.81
   2 ?   -3.2   0.0       3.1   9.2e+03      35      62 ..     253     280 ..     226     297 .. 0.64

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 2.8e-06
                      EEEE--.SHHHHHHHHHHHCTCCT-G..EEEEEESSHHHHHHHHCHHTTTCEEEEE--TTTHHHHHHHHHTTS..SEEEE-SSGG........G CS
  Sacchrp_dh_NADP   1 vliiGa.GsvGqavaellarhfdvda..eitvadrskeklealaakalgvrfeaialdaenyeavLaallkeg..dlvvnlsppi........s 81 
                      + ++Ga G+ G +v++ l++   + +  +i  ++r+ +k  ++a+k++++ +e i+ d + +++ L+++lk+    ++v   + +        +
       EEA22466.1  33 ITVFGAtGNQGGSVIRSLLADPVLAKeyKIRGITRDVTK--EAAKKLSSQGVEMITADMSSPSS-LDEALKGShtVFLVTNFWETmskdtevaQ 123
                      6799****************9988775666666666666..8888899****************.******99876666666666666667777 PP

                      HHHHHHHHHHHT-E CS
  Sacchrp_dh_NADP  82 sldvlkaCietgvh 95 
                      + +v++aC  tgv 
       EEA22466.1 124 GKAVADACKNTGVK 137
                      77777777777775 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 3.1
                      HHHHHHHCHHTTTCEEEEE--TTTHHHH CS
  Sacchrp_dh_NADP  35 eklealaakalgvrfeaialdaenyeav 62 
                      ++l  +++++lgv++ ai++  e  ++ 
       EEA22466.1 253 RQLTDEISQTLGVKAAAIQIPEETFKSF 280
                      3444455555666666666666665555 PP

>> FtsJ  FtsJ-like methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0     7e-05      0.21      62     149 ..      61     145 ..       6     166 .. 0.81
   2 ?   -2.0   0.0       1.1   3.2e+03      25      53 ..     217     248 ..     196     265 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 7e-05
                 TEEEECS-CCCSSHHHHHCHCHHHSSEEEEEE--S-SS-CHHHHHHHHHCCCCHHHHCCHC.CCCECCCEEEECCCHCCCHHHHHHH.HH CS
        FtsJ  62 gvttiqgditdpetiekikealserkvdlvvsDgapdvsgvhdldeylqsqLllaalelal.kllkpggtfvlkifrgeeteallkq.lk 149
                 +++ i+ d+t+++++++ +     ++v+++++D+++  s+ ++l+   ++ L+ + +e+++ ++   +g  v+ +++++ ++ l+   l+
  EEA22466.1  61 KIRGITRDVTKEAAKKLSS-----QGVEMITADMSSPSSLDEALKGSHTVFLVTNFWETMSkDTEVAQGKAVADACKNTGVKHLIFSsLR 145
                 5666788888888877666.....48*********9999999999999999999999998855666778999999998888866655466 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.1
                 EEECT-TTSHHHHHHCCT.T....-SEEEEEE CS
        FtsJ  25 vvDlgaaPGgwsqvllqrlga...kgkvvavD 53 
                 v+D+   +G + + ++++  +   k  ++a D
  EEA22466.1 217 VFDVEEDTGKFVKAVVKNYPNiigKRILIATD 248
                 88888999999999999974344345566666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (333 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       641  (0.0357521); expected 358.6 (0.02)
Passed bias filter:                      587  (0.0327403); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.40
# Mc/sec: 2482.43
//
Query:       EEA22467.1  [L=252]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.2e-13   48.4   0.0    3.1e-12   46.6   0.0    1.9  2  Acetyltransf_10  Acetyltransferase (GNAT) domain
    2.2e-10   40.8   0.0    2.4e-09   37.5   0.0    2.3  1  Acetyltransf_1   Acetyltransferase (GNAT) family
    6.1e-10   39.4   0.0      2e-08   34.6   0.0    2.8  4  Acetyltransf_7   Acetyltransferase (GNAT) domain
    0.00034   20.7   0.0     0.0016   18.5   0.0    2.1  2  Acetyltransf_CG  GCN5-related N-acetyl-transferase
      0.006   16.7   0.3      0.029   14.5   0.0    2.2  2  Acetyltransf_9   Acetyltransferase (GNAT) domain
     0.0077   16.2   0.0      0.015   15.3   0.0    1.4  1  FR47             FR47-like protein
  ------ inclusion threshold ------
      0.078   12.6   0.1       0.11   12.1   0.1    1.2  1  tRNA_anti-like   tRNA_anti-like


Domain annotation for each model (and alignments):
>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0       0.6   1.5e+03      20      47 ..      46      75 ..      22      79 .. 0.76
   2 !   46.6   0.0   1.2e-15   3.1e-12      44     114 ..     136     204 ..      86     210 .. 0.83

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.6
  Acetyltransf_10 20 ealrerieegealllvaeeg..gkivGvie 47
                      + +  i+++e+++lva +   +++vG+++
       EEA22467.1 46 ITTKTAINNPENIFLVAADPatDEVVGFVR 75
                     556677888888888887754588999886 PP

  == domain 2  score: 46.6 bits;  conditional E-value: 1.2e-15
  Acetyltransf_10  44 GvielrdgshisllfVdpeyrgqGigkaLleaveeeaekdgikleltvnaspyavpfYeklGFkavgeeqe 114
                      Gv++ +++ +i +l+++p+++++Gig++Ll av+++ + +  kl + + +s +a p+Y+klGF++ g+ + 
       EEA22467.1 136 GVAKGQRHYYIKHLMINPAHQRRGIGAKLLSAVLAKSDAE--KLPTFLTSSAEAHPLYMKLGFVDFGPDFR 204
                      788778888***************************8544..338********************999876 PP

>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.5   0.0   9.2e-13   2.4e-09      30     117 .]      53     196 ..      21     196 .. 0.75

  Alignments for each domain:
  == domain 1  score: 37.5 bits;  conditional E-value: 9.2e-13
                     STTC.EEEEEEET...TEEEEEE...............................................EEEEEET..........TSTTEEEE CS
  Acetyltransf_1  30 leae.gllvaeed...geliGfi...............................................sllkipd..........ekggvayi 63 
                     +++e  +lv   d   +e++Gf+                                                ++k++d            ++++yi
      EEA22467.1  53 NNPEnIFLV-AADpatDEVVGFVryavvpekkpeeakkeeekdaksqldrtqpefanlfapkehvkelweEFSKRDDemdacyegvaKGQRHYYI 146
                     344423333.3333568899999888888888888888888888888888888888888888877777774444444666666677777799*** PP

                     EEEEESGGGTTSSHHHHHHHHHHHHHHHTTESEEEEEEETTEHHHHHHHHHTTE CS
  Acetyltransf_1  64 eslaVspeyrgkGlGsaLlealeerareegikkivlaveedndaairlYeklGF 117
                       l+++p+++++G+G +Ll a++ +   e +   +l    +   a++lY+klGF
      EEA22467.1 147 KHLMINPAHQRRGIGAKLLSAVLAKSDAEKLPT-FL---TSSAEAHPLYMKLGF 196
                     ***********************9888888888.88...67889*********9 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0       3.9   9.9e+03      25      36 ..      31      42 ..      15      42 .. 0.59
   2 ?    1.3   0.0      0.19   4.8e+02       3      23 ..      57      79 ..      54      92 .. 0.75
   3 !   34.6   0.0   7.6e-12     2e-08      21      75 ..     141     197 ..     117     198 .. 0.70
   4 ?   -2.3   0.0       2.4   6.1e+03      39      52 ..     208     222 ..     206     238 .. 0.64

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 3.9
                    TCTEEEEE-GGG CS
  Acetyltransf_7 25 aeitrlaVdpey 36
                    ++ ++la++p y
      EEA22467.1 31 FYSGFLATHPRY 42
                    344448888866 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.19
                    EEEEEEEET..TEEEEEEEEEEE CS
  Acetyltransf_7  3 gevfVaedd..gkivGfialsll 23
                    + ++Va d   +++vGf++++++
      EEA22467.1 57 NIFLVAADPatDEVVGFVRYAVV 79
                    345666555999*****998765 PP

  == domain 3  score: 34.6 bits;  conditional E-value: 7.6e-12
                     EEESTCTEEEEE-GGGTTSSHHHHHHHH...TTSEEEEE.EEEE.THH.HHHHHHHHTTEE CS
  Acetyltransf_7  21 slldaeitrlaVdpeyrgkGiGraLlea...aekgiile.qlel.nae.kaikfYeklGFe 75 
                     +++ ++i++l ++p+++++GiG +Ll a   + +  + +  + l + + +a+++Y klGF+
      EEA22467.1 141 QRH-YYIKHLMINPAHQRRGIGAKLLSAvlaK-SDAE-KlPTFLtS-SaEAHPLYMKLGFV 197
                     333.58888*****************984431.2222.22334432.248999*******8 PP

  == domain 4  score: -2.3 bits;  conditional E-value: 2.4
                     SSHHHHHHHHTT.SE CS
  Acetyltransf_7  39 kGiGraLleaae.kg 52 
                      G +r+++e+ e  g
      EEA22467.1 208 EGWARRIMELDEeLG 222
                     588899998722233 PP

>> Acetyltransf_CG  GCN5-related N-acetyl-transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0         1   2.6e+03       8      21 ..      67      80 ..      59      94 .. 0.73
   2 !   18.5   0.0   6.4e-07    0.0016      19      57 ..     138     176 ..     120     186 .. 0.82

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 1
  Acetyltransf_CG  8 egeevafleYevrk 21
                     ++e v+f++Y v +
       EEA22467.1 67 TDEVVGFVRYAVVP 80
                     56789999997544 PP

  == domain 2  score: 18.5 bits;  conditional E-value: 6.4e-07
  Acetyltransf_CG  19 vrkegvldfthTeVpeelrGkGiAkkLvkaalddareeg 57 
                      ++++ ++ + h  ++++++++Gi++kL  a+l +  +e+
       EEA22467.1 138 AKGQRHYYIKHLMINPAHQRRGIGAKLLSAVLAKSDAEK 176
                      4667799*************************9877765 PP

>> Acetyltransf_9  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.1         1   2.6e+03      13      13 ..      95      95 ..      62     134 .. 0.57
   2 !   14.5   0.0   1.1e-05     0.029      75     125 ..     145     196 ..     139     198 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 1
                    H CS
  Acetyltransf_9 13 v 13
                    +
      EEA22467.1 95 A 95
                    2 PP

  == domain 2  score: 14.5 bits;  conditional E-value: 1.1e-05
                     EEEEEEE-CCGTTS-HHHHHHHHHHHHHHHTT--EEEE--SS.HHHHHTTT- CS
  Acetyltransf_9  75 gvtgVavapehrgrgvlskLlaraleemreegqplsllfPss.ipiYrrfGy 125
                     ++   + +p h++rg+  kLl ++l++ ++e+ p  l   ++  p+Y ++G+
      EEA22467.1 145 YIKHLMINPAHQRRGIGAKLLSAVLAKSDAEKLPTFLTSSAEaHPLYMKLGF 196
                     7778899************************99977766655379****998 PP

>> FR47  FR47-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   5.7e-06     0.015      23      77 ..     145     196 ..     126     204 .. 0.80

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 5.7e-06
                 SEEEEEE-GGG-SSSHHHHHHHHHHHHHHHS-S-EEEEEETT-HHHHHHHHHHT- CS
        FR47  23 elgalqvlpehrrrGlgsrlvkalakeiaergktvllvvvasNtpsirlyeklGf 77 
                 ++  l ++p h+rrG g +l +a+    a+ + + l    +s  ++  ly klGf
  EEA22467.1 145 YIKHLMINPAHQRRGIGAKLLSAVL---AKSDAEKLPTFLTSSAEAHPLYMKLGF 196
                 688899***********99988875...55555555556667788999******9 PP

>> tRNA_anti-like  tRNA_anti-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.1   4.4e-05      0.11      18      86 ..      71     136 ..      42     138 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 4.4e-05
                     XXXXXXXXXXXXXXXXXXXX---HHHHHTS-..............EEEHHHHHHHHHH-HHHHHHHHTT CS
  tRNA_anti-like  18 llfvialvaqaaesardkekaekedadatlaeakakpeavaekasqisArdLlaeYdkNevkadkkYkG 86 
                     ++fv ++v  + ++ ++++k+e++da+ +l   + +pe   + a++  +++L++e++k   + d  Y G
      EEA22467.1  71 VGFVRYAVVPE-KKPEEAKKEEEKDAKSQL--DRTQPEFANLFAPKEHVKELWEEFSKRDDEMDACYEG 136
                     45555533222.334445555555555555..5999***********************9999999988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (252 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       827  (0.0461264); expected 358.6 (0.02)
Passed bias filter:                      603  (0.0336327); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 1858.03
//
Query:       EEA22468.1  [L=233]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
     0.0032   17.9   1.5       0.13   12.7   0.4    3.0  2  NuiA       Nuclease A inhibitor-like protein
  ------ inclusion threshold ------
      0.012   15.6   0.2      0.018   15.0   0.2    1.2  1  Smg4_UPF3  Smg-4/UPF3 family


Domain annotation for each model (and alignments):
>> NuiA  Nuclease A inhibitor-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0      0.06   5.4e+02      16      56 ..      59      98 ..      24     102 .. 0.64
   2 !   12.7   0.4   1.5e-05      0.13      13     129 ..     114     232 ..     104     233 .] 0.62

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.06
                EESSSEE--EEEEESS-SSSSSTTHHHHHHT-TTTSSCEEE CS
        NuiA 16 ymSeSdypfeviswevdakeltkekllketghpadtpvesv 56
                + S+Sdy   + + +++ +++  ++  +++  ++++++++ 
  EEA22468.1 59 MASDSDYMAFLDKANKQ-RDAGRDEARTKASTQPSKQIQTE 98
                56777775433333333.24444444445555556666655 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 1.5e-05
                 TS-EESSSEE--EEEE..ESS-SS..SSSTTHHHHHHT-TTTSSCEEE-HHHHTTCTT--SSTS-HHHHHHHHHHHHHHHHHTTHSSEEEEEEE..SSS CS
        NuiA  13 gLLymSeSdypfevis..wevdak..eltkekllketghpadtpvesveldeflrnalteeewyeeeekeeaqrfqtlvklLksnLtdlkvyRv..gev 105
                 + +y+Se+d+pfe++   w+ + +     +++++++++  ++  +e ++     ++ ++ ++ y++e ++  +   +     +++  ++kvyRv  g+ 
  EEA22468.1 114 DAFYVSETDEPFEPVAlsWKGASSgkWPGTDEFASLITSGSKPDIEILS-----EKSFDPRSQYSSEIQAVRAAVAASDSKVNESDVKVKVYRVevGNS 207
                 559**********986114444433234455666666644444444444.....344445555555555555555555566677777899999733568 PP

                 SEEEEEEEC-.TTSSEEEEEEEEE- CS
        NuiA 106 eidvyilGkt.ksgelaGlkTkvve 129
                  ++ +i+  + ++g+++Gl  k++e
  EEA22468.1 208 RVEYWIIALDgAEGKIVGLMAKAIE 232
                 8888999865378999999999998 PP

>> Smg4_UPF3  Smg-4/UPF3 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.0   0.2     2e-06     0.018      92     149 ..      33      93 ..      19     116 .. 0.71

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 2e-06
   Smg4_UPF3  92 fApyqkvpkkk.....kkkkdakqgtIekDpeylaFleslekeeeekeseseeeklaeeaeek 149
                 +Ap q+ ++++     ++++ +   t  +D++y+aFl + +k++++   e+   ++a+++ +k
  EEA22468.1  33 VAPAQRPTSTQrtnlfNSQSPSSIRTMASDSDYMAFLDKANKQRDAGRDEA--RTKASTQPSK 93 
                 6788887554446788888889999****************8888744443..4444333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (233 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       626  (0.0349155); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.31s 00:00:00.84 Elapsed: 00:00:00.52
# Mc/sec: 1353.78
//
Query:       EEA22469.1  [L=416]
Description: argininosuccinate synthase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   5.7e-151  503.2   0.0   6.5e-151  503.0   0.0    1.0  1  Arginosuc_synth  Arginosuccinate synthase
     0.0036   16.1   0.0     0.0053   15.6   0.0    1.3  1  tRNA_Me_trans    tRNA methyl transferase
     0.0083   15.6   0.0      0.012   15.1   0.0    1.2  1  QueC             Queuosine biosynthesis protein QueC


Domain annotation for each model (and alignments):
>> Arginosuc_synth  Arginosuccinate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  503.0   0.0  1.1e-154  6.5e-151       1     387 [.       7     402 ..       7     403 .. 0.97

  Alignments for each domain:
  == domain 1  score: 503.0 bits;  conditional E-value: 1.1e-154
  Arginosuc_synth   1 vLaysGGlDtsviikllkeklgeeviavavdvGqeeedldevkekalklgavksvvvDakeefvedyifpaikanalYedrYllgtalaRPlia 94 
                      +LaysGGlDtsvi+k+l e++ ++v+a+++dvGq  ed+ ++++kal++gavk+vv D k+efve+ +f+ai+ na++ed+Yllgt+laRP+ia
       EEA22469.1   7 CLAYSGGLDTSVILKWLIEQG-YDVVAFMADVGQA-EDFAAAEKKALAIGAVKFVVEDLKQEFVEELCFRAIQCNAIFEDQYLLGTSLARPVIA 98 
                      79******************9.*************.********************************************************** PP

  Arginosuc_synth  95 kklvevakkegaeavahGctGkGnDqvRfevsirslaPdlkviaPvRelelt.....ReeeieyakekgipvevtkkkpysiDenllgrsieag 183
                      ++++ va+++++ av+hGctGkGnDqvRfe+++++ +P +kviaP+R +e++     R++ ++y+++ gipv +tk+kp+s+Denl++ s+eag
       EEA22469.1  99 RAQMRVAQQNDCVAVSHGCTGKGNDQVRFELAFYAIQPTIKVIAPWRLPEFFerfagRNDLLDYSAKVGIPVTSTKAKPWSMDENLAHCSYEAG 192
                      ***************************************************99***************************************** PP

  Arginosuc_synth 184 iLedpknappediyeltkdpakapdepeeveiefekGvPvald...geelsv.lelieklneiagkhGvGRiDivedRlvglksReiYeapaal 273
                      iLedp+ +pp d+++lt++p +ap++pee +i+fekG+P +l    g++++  l+++++ln i++khG+GR+Dive+R++g+ksR++Y+ pa +
       EEA22469.1 193 ILEDPNITPPADMWKLTDSPLDAPNTPEEFSISFEKGIPTKLVtpsGQTVTGsLDIFTTLNAIGRKHGIGRVDIVENRFIGIKSRGCYDSPAMT 286
                      *****************************************977777777666***************************************** PP

  Arginosuc_synth 274 vLikahkdlekltlerevakfkkivee.kyaelvYkGlwfsPlkealdafiektqervtGtvrvklfkGsvvvlgResees.lYdeelasydee 365
                      +L++ah dle l+l+rev+ +++++ + ++++l+Y+Gl+fsP++e +++ +  +q+ v+Gtvr+  +kG+v +lgR se++ lY++e +s+d+ 
       EEA22469.1 287 ILRAAHVDLEGLVLDREVRSLRDQFVTfTWSKLLYNGLYFSPEREFIEKSVVASQDTVNGTVRLCAYKGAVSILGRFSETEkLYSAEESSMDTL 380
                      **********************9876526*************************************************9988************ PP

  Arginosuc_synth 366 defdqkeaeGfikihglqakly 387
                      ++f + +++Gfi i  ++  +y
       EEA22469.1 381 TDFSPVDTTGFIGISKIRLAKY 402
                      **************99988766 PP

>> tRNA_Me_trans  tRNA methyl transferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   8.9e-07    0.0053       2      45 ..       5      47 ..       4      85 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 8.9e-07
  tRNA_Me_trans  2 kvvvalSgGVDSsvaaallkeqgyevigvflklweeedeegkec 45
                   kv+ a SgG D sv +  l eqgy+v++++  + + ed +  + 
     EEA22469.1  5 KVCLAYSGGLDTSVILKWLIEQGYDVVAFMADVGQAEDFAA-AE 47
                   7999***********************98887777777665.33 PP

>> QueC  Queuosine biosynthesis protein QueC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   2.1e-06     0.012       4      48 ..       8      52 ..       5      94 .. 0.72

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 2.1e-06
                EE--SSHHHHHHHHHHHHH-SEEEEEEEESS-TTSHHHHHHHHHH CS
        QueC  4 vllSGGlDSttvlalakkegkevealtfdYgqrhkkeleaakkia 48
                +  SGGlD +++l +  ++g+ v a   d gq ++      k++a
  EEA22469.1  8 LAYSGGLDTSVILKWLIEQGYDVVAFMADVGQAEDFAAAEKKALA 52
                557*****************************8765554444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (416 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       410  (0.022868); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.48
# Mc/sec: 2617.26
//
Query:       EEA22470.1  [L=320]
Description: O-methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-15   57.9   0.0    3.4e-15   56.5   0.0    1.7  2  Methyltransf_25  Methyltransferase domain
    3.5e-13   49.6   0.0      5e-13   49.1   0.0    1.3  1  Methyltransf_31  Methyltransferase domain
    1.8e-11   44.6   0.0    3.7e-11   43.7   0.0    1.5  1  Methyltransf_12  Methyltransferase domain
    5.5e-11   42.6   0.0    7.1e-11   42.2   0.0    1.2  1  Methyltransf_23  Methyltransferase domain
    1.4e-10   41.7   0.0    2.9e-10   40.7   0.0    1.6  1  Methyltransf_11  Methyltransferase domain
    4.3e-05   23.1   0.0    6.7e-05   22.5   0.0    1.3  1  MTS              Methyltransferase small domain
    0.00029   21.0   0.0    0.00051   20.2   0.0    1.4  1  FtsJ             FtsJ-like methyltransferase
    0.00066   19.7   0.0    0.00097   19.2   0.0    1.4  1  Methyltransf_32  Methyltransferase domain
     0.0014   18.0   0.0     0.0024   17.2   0.0    1.4  1  Methyltransf_2   O-methyltransferase domain
     0.0085   15.9   0.0       0.04   13.7   0.0    2.1  2  DUF4817          Helix-turn-helix domain (DUF4817)
  ------ inclusion threshold ------
      0.021   14.3   0.0        1.2    8.6   0.0    2.3  2  CheR             CheR methyltransferase, SAM binding domain
      0.063   12.7   0.0       0.13   11.7   0.0    1.4  1  TehB             Tellurite resistance protein TehB
      0.065   12.7   0.0       0.12   11.9   0.0    1.4  1  Methyltransf_5   MraW methylase family


Domain annotation for each model (and alignments):
>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.5   0.0   2.5e-18   3.4e-15       1      97 []      91     185 ..      91     185 .. 0.94
   2 ?   -2.3   0.0       5.3   7.4e+03      29      43 ..     198     212 ..     195     262 .. 0.55

  Alignments for each domain:
  == domain 1  score: 56.5 bits;  conditional E-value: 2.5e-18
                      EEEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHHTTTTEEEEESBCCGBS..SSTTTEEEEEEESTGGGSSHHHHHHHHHHHHHH CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlgkakvtgvDiseemleaareraeeeglnvefvqgdaedlp..fedgsfDlvvssgalhhlsdedlekalkeiarv 92 
                      v+dlGcG+G+ t+ l  ++++a++ g+D s++m+e+ar+r+    ++vef+ gd++++     ++++D+ +s+ ++++++ e++  +++++ ++
       EEA22470.1  91 VVDLGCGPGNSTEVLVSKWPDARISGMDSSPDMIEKARARL----PSVEFELGDLNTWTptNTEEKVDVFFSNAVFQWVPSEKRLPLISRFIEM 180
                      89*****************99********************....9*********9986334888*******666******************* PP

                      EEEEE CS
  Methyltransf_25  93 LkpgG 97 
                        pgG
       EEA22470.1 181 QAPGG 185
                      ***99 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 5.3
                      SSHHHHHHHHHHHHH CS
  Methyltransf_25  29 iseemleaareraee 43 
                      +s++m+++++++a++
       EEA22470.1 198 PSHAMMRETASEANK 212
                      566666665555532 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.1   0.0   3.6e-16     5e-13       5     114 ..      89     218 ..      85     260 .. 0.67

  Alignments for each domain:
  == domain 1  score: 49.1 bits;  conditional E-value: 3.6e-16
  Methyltransf_31   5 lrvlDlGCGtGeltfelaeelgpkaevvGiDiseeaielArenaqklgldnveFeqgdiee.leklledekfDlilsnevl..naladpdkile 95 
                       rv+DlGCG G+ t +l     p+a++ G D s+++ie+Ar++     l  veFe gd ++  +++ e ek+D+ +sn+v+           + 
       EEA22470.1  89 RRVVDLGCGPGNSTEVLV-SKWPDARISGMDSSPDMIEKARAR-----LPSVEFELGDLNTwTPTNTE-EKVDVFFSNAVFqwVPSEKRLPLIS 175
                      689***************.6689*******************8.....668**********9998744.89**********5533344445677 PP

  Methyltransf_31  96 eiervlkpggilliedpr........................l 114
                      + ++   pgg+++ + p+                        l
       EEA22470.1 176 RFIEMQAPGGVFAFQVPDnflepshammretaseankpwtatL 218
                      8888888888888888885333333333332233333322221 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.7   0.0   2.7e-14   3.7e-11       1      99 []      92     187 ..      92     187 .. 0.95

  Alignments for each domain:
  == domain 1  score: 43.7 bits;  conditional E-value: 2.7e-14
  Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvelealdlldldggssfDlvvasnvlhhl..kdirevldnirkl 92 
                      +++GcG G+ +++l  k pd+++ g+D sp++ie+a+++l + e +  + ++++ ++ +     +++D+ +++ v++++  +++  +++++ ++
       EEA22470.1  92 VDLGCGPGNSTEVLVSKWPDARISGMDSSPDMIEKARARLPSVEFELGDLNTWTPTNTE-----EKVDVFFSNAVFQWVpsEKRLPLISRFIEM 180
                      59*******************************************************76.....39**************77777********* PP

  Methyltransf_12  93 LkpgGrl 99 
                       +pgG++
       EEA22470.1 181 QAPGGVF 187
                      *****86 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.2   0.0   5.1e-14   7.1e-11       3     125 ..      70     205 ..      65     271 .. 0.76

  Alignments for each domain:
  == domain 1  score: 42.2 bits;  conditional E-value: 5.1e-14
  Methyltransf_23   3 aqreeelsdklerllpklraggrvLdiGcGtGillevl.rengf.svtgvDlspeaveiae...........kakkaqkdqfdeqeaae..pqg 81 
                       +r + ++d+l++++    ++ rv+d+GcG G+ +evl ++++   + g+D sp ++e+a+                       + +++   ++
       EEA22470.1  70 QERTRPVRDLLAQIP--ASSPRRVVDLGCGPGNSTEVLvSKWPDaRISGMDSSPDMIEKARarlpsvefelgD----------LNTWTPtnTEE 151
                      455577777777777..699************99999978886579**************9855444433333..........44444411366 PP

  Methyltransf_23  82 kfdlIvlrevlehvpd..ppellrqiatllkpgGylllseplasl........k 125
                      k d+  ++ v+ +vp+     l++++ ++ +pgG++ +++p++ l        +
       EEA22470.1 152 KVDVFFSNAVFQWVPSekRLPLISRFIEMQAPGGVFAFQVPDNFLepshammrE 205
                      ***************8445679*******************9987554444431 PP

>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.7   0.0   2.1e-13   2.9e-10       1      96 []      92     189 ..      92     189 .. 0.88

  Alignments for each domain:
  == domain 1  score: 40.7 bits;  conditional E-value: 2.1e-13
                      EEET-TTSHHHHHHHHTT..SEEEEEES-HHHHHHHHHHCCHHT-EEEETTEECCC.TS.S-TT-EEEEEEES-CCC-..CCHHHHHHHHHHHE CS
  Methyltransf_11   1 LdvGcGtGrlaealakrg..arvvgvDlskemlklakekaseeglkvefvvadaek.lp.fednsfDlvvssevlhhv..edpekalkeiaRvL 88 
                      +d+GcG G  +e l ++   ar+ g+D s+ m++ a+++ +     vef  +d+ + +p   ++++D+ +s+ v+++v  e++  +++ +  + 
       EEA22470.1  92 VDLGCGPGNSTEVLVSKWpdARISGMDSSPDMIEKARARLPS----VEFELGDLNTwTPtNTEEKVDVFFSNAVFQWVpsEKRLPLISRFIEMQ 181
                      59*************8878**************999999887....56899****944734558**************8888889999999999 PP

                      EEEEEEEE CS
  Methyltransf_11  89 kpgGllvi 96 
                       pgG++++
       EEA22470.1 182 APGGVFAF 189
                      99999876 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5   0.0   4.9e-08   6.7e-05      23     104 ..      79     159 ..      75     183 .. 0.82

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 4.9e-08
                 HHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE- CS
         MTS  23 LletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvleeveekkfdlivsN 104
                 Ll ++p++  ++v+DlGcG G  + +l +++p+a++  +d +   +e a++ l + ++e+  +++    ++e +k+d+  sN
  EEA22470.1  79 LLAQIPASSPRRVVDLGCGPGNSTEVLVSKWPDARISGMDSSPDMIEKARARLPSVEFELGDLNTWTPTNTE-EKVDVFFSN 159
                 788899999999**************************************9999888874444443444444.678877777 PP

>> FtsJ  FtsJ-like methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.0   3.7e-07   0.00051      23      81 ..      89     155 ..      56     211 .. 0.77

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 3.7e-07
                 -EEEECT-TTSHHHHHHCCT.T.-SEEEEEESSSS......HHHTTEEEECS-C...CCSSHHHHHCH CS
        FtsJ  23 ktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm......aplpgvttiqgdi...tdpetiekike 81 
                 ++vvDlg++PG+ ++vl+ +    +++ ++D  p       a lp v++  gd    t  +t+ek+  
  EEA22470.1  89 RRVVDLGCGPGNSTEVLVSKWPD-ARISGMDSSPDmiekarARLPSVEFELGDLntwTPTNTEEKVDV 155
                 67******************976.********888799765555999998888833333344444444 PP

>> Methyltransf_32  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   0.0     7e-07   0.00097      13      94 ..      76     153 ..      70     233 .. 0.84

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 7e-07
  Methyltransf_32  13 vakllkelakesgaltvvDvGaGkgYLsfvlalkeke.yklkvvgidakeelvekaekraeklgkkfnkrlsfaelsieeats 94 
                      v++ll+++  +s++ +vvD+G+G g  + vl +   +    ++ g+d++ +++eka++r   ++ ++  +l++++ +++e++ 
       EEA22470.1  76 VRDLLAQI-PASSPRRVVDLGCGPGNSTEVLVS---KwPDARISGMDSSPDMIEKARARLPSVEFEL-GDLNTWTPTNTEEKV 153
                      56667774.556699******************...5579*******************99998666.777777776666555 PP

>> Methyltransf_2  O-methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   1.8e-06    0.0024      50     121 ..      75     142 ..      48     169 .. 0.85

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 1.8e-06
                     HHHHHHHSS-GGG-SEEEEET-TTSHHHHHHHHH-TT-EEEEEE-.HHHHHHHHHHS-----TTEEEEES-TT CS
  Methyltransf_2  50 vakkvleafdleglkslvDvGGGtGalakaivsayPtikvivfDl.peVveaAkehlsageeervefvgGdff 121
                      ++++l+++  ++ +++vD+G G G   +  vs++P  +++ +D  p+ +e+A+ +      ++vef  Gd+ 
      EEA22470.1  75 PVRDLLAQIPASSPRRVVDLGCGPGNSTEVLVSKWPDARISGMDSsPDMIEKARAR-----LPSVEFELGDLN 142
                     467889999999999*****************************549*********.....578888888875 PP

>> DUF4817  Helix-turn-helix domain (DUF4817)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.7   0.0   2.9e-05      0.04       9      42 ..       9      42 ..       7      44 .. 0.95
   2 ?   -1.5   0.0       1.7   2.3e+03       1      14 [.     279     292 ..     279     296 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 2.9e-05
     DUF4817  9 VkaYykngesvtatqrafrrrFpnrsvPsrstir 42
                + ++++ g+s+++++ afr+ F    vP ++tir
  EEA22470.1  9 ILCHHQLGQSIIKVLPAFRQSFRTLPVPKQQTIR 42
                67999****************************8 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1.7
     DUF4817   1 TleqRifiVkaYyk 14 
                 + e+R  +V+aY +
  EEA22470.1 279 SEEERKGFVEAYLE 292
                 5699********76 PP

>> CheR  CheR methyltransferase, SAM binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.0     0.039        53      55      82 ..     108     129 ..      64     131 .. 0.73
   2 ?    8.6   0.0   0.00085       1.2     120     170 ..     134     186 ..     130     189 .. 0.90

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.039
                 CHSTTTSSS.-EEEEEEESSCHHHHHHHH CS
        CheR  55 etlpkaakl.kvkilAtDidlkvlekAka 82 
                 +       + + +i + D++  ++ekA+a
  EEA22470.1 108 K-------WpDARISGMDSSPDMIEKARA 129
                 3.......336889*************97 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.00085
                 EEEEE--TTT..-SGGG--EEEEEE-SSGGGC-CHHHHHHHHHHHCCEEEEEE CS
        CheR 120 vkFeklnlle..kksvlgklDvifcrnvliYfdeetqekvlerfaeklkpggl 170
                 v+Fe  +l++    + ++k+Dv f+  v+ +  +e++  +++rf e+ +pgg+
  EEA22470.1 134 VEFELGDLNTwtPTNTEEKVDVFFSNAVFQWVPSEKRLPLISRFIEMQAPGGV 186
                 889988888876788999*********************************98 PP

>> TehB  Tellurite resistance protein TehB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   9.2e-05      0.13       8     128 ..      65     185 ..      57     191 .. 0.71

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 9.2e-05
                 HHHHHHT-----HHHHHHCCCS-S-EEEEES-TTSHHHHHHHHTT-EEEEEES-HHHHHHHHHHHHHTT-TTEEEEE--GGG...----S-EEEEEEES CS
        TehB   8 yfskkynltathsevveavkivkpgkvldlgcgqgrnslylsllgydvtawdknensiafleeikekenlknistalydine...aklderydfilstv 103
                 y +   + t+   +++  +   +p +v+dlgcg g  +  l  +  d   +   ++s  ++e+   +  l +++ +l d+n+   ++ +e+ d  +s  
  EEA22470.1  65 YLKFEQERTRPVRDLLAQIPASSPRRVVDLGCGPGNSTEVLVSKWPD-ARISGMDSSPDMIEKA--RARLPSVEFELGDLNTwtpTNTEEKVDVFFSNA 160
                 5555566677777888888999*************776666554433.3334444455555543..456777888888888633357899999999999 PP

                 SGGGS-GGGHHHHHHHHHHTEEEEE CS
        TehB 104 vlmfleaeripsiienmqectkvgg 128
                 v+ ++ +e+   +i+ + e+  +gg
  EEA22470.1 161 VFQWVPSEKRLPLISRFIEMQAPGG 185
                 9999988877778888888888887 PP

>> Methyltransf_5  MraW methylase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   8.6e-05      0.12      19      68 ..      86     135 ..      75     155 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 8.6e-05
                     -TT-EEEES--TTSHHHHHHHTT--TTEEEEEES-HHHHHHHTT.....- CS
  Methyltransf_5  19 kedgvyiDaTlGaggHsealLeqlselrligidrDksalarakerLkefe 68 
                      +    +D   G g  +e l ++ ++ r+ g+d  ++++++a++rL + e
      EEA22470.1  86 SSPRRVVDLGCGPGNSTEVLVSKWPDARISGMDSSPDMIEKARARLPSVE 135
                     5566679**************************************98765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (320 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       554  (0.0308997); expected 358.6 (0.02)
Passed bias filter:                      511  (0.0285013); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.67u 0.38s 00:00:01.05 Elapsed: 00:00:00.57
# Mc/sec: 1689.55
//
Query:       EEA22471.1  [L=520]
Description: MFS monosaccharide transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-95  321.1  25.5    3.2e-94  316.4  25.5    2.0  1  Sugar_tr  Sugar (and other) transporter
    2.3e-19   69.5  37.9    1.3e-09   37.5  17.2    3.1  3  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
       0.76    8.1   6.8      0.056   11.8   1.6    1.6  2  MFS_3     Transmembrane secretion effector
        2.4    8.3  22.1        1.1    9.5   6.0    3.1  2  DUF3792   Protein of unknown function (DUF3792)


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  316.4  25.5   7.1e-98   3.2e-94       4     452 .]      20     455 ..      17     455 .. 0.93

  Alignments for each domain:
  == domain 1  score: 316.4 bits;  conditional E-value: 7.1e-98
                 HHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTT.SS CS
    Sugar_tr   4 vaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgk.ns 101
                 + +lg llfgYd gv++++++  +f   f+++k +s+ +       l+++++ +G+++G++fa + gd++GR++ ++i+a +++ g ++q++a  +   
  EEA22471.1  20 IGTLGFLLFGYDQGVMSGIISDAAFNDVFTATKGNSTMQ------ALVTAVYELGCLAGAIFALFRGDMIGRRWMIIIGASVMILGVIIQVTAFPGhVP 112
                 667788************************999999776......5*********************************************99866578 PP

                 -TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHH CS
    Sugar_tr 102 vevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPrylve 200
                 + +++vgR+++Gig G+ + ++P+y++E                 i++G l+a+++++g     ++  wr+++++q+v+ +l++++++ lP+SPryl++
  EEA22471.1 113 LAQFMVGRIVTGIGNGMNTSTIPTYQAECG--------------TIAIGTLIAYWIDYGAHFGPSDLVWRFPIAFQVVFGILIIVGMYYLPDSPRYLIT 197
                 99**************************74..............599*************999999********************************* PP

                 TT-HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH..........HTTHHHHSH.....HHHHHHHHHHHHHHTTHHHHHHHTTTHHHH.SS-THH.. CS
    Sugar_tr 201 kgkeeeakevlaklrgeedadrelaeekdsleaeqeee.....kaswkellsskt..vrqrlligvvlqifqqltGinaimyysptifen.lglsks.. 289
                 ++k e+ + vla l g e  d e +  k+    +++++      + +k ll+     +++r+lig+  qifqql+G+na++yy p+++e+ lg s+   
  EEA22471.1 198 RNKIEDGEYVLAALIGHEITDHETQIQKQLVLDSVRASgaldkDVRYKDLLTGGHtqHFRRMLIGASSQIFQQLSGCNAVIYYLPVLLEQsLGQSTNqa 296
                 *************99998888888888887777777777898877777777663359*****************************9986267776699 PP

                 HHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHH CS
    Sugar_tr 290 llvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskal 388
                 ll+ +i ++  +v+  +++f+++++GRR+l+l G++g++++++i    a+l++++ k  +++a+++++l++++f+++w p+pw++ +E++p ++R+ka 
  EEA22471.1 297 LLIGGINMICYAVFATFSWFFIEKIGRRKLFLGGTFGQLAAMIITF--ACLIPNN-KQVANGAVFGLFLYMCFFGATWLPLPWLYPAEISPIKTRAKAN 392
                 9999999999999999999**************************8..8888888.5899*************************************** PP

                 HHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 389 aiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 a+++++nwl+nf i +++p+++++ig + ++l+fa++++ fi f+++f+pet gr+leei+ +f
  EEA22471.1 393 AVSTCCNWLFNFTIVMITPVMVSSIG-WRTYLFFAVMNASFIPFIWLFYPETSGRSLEEIDIIF 455
                 **************************.*********************************9876 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.3   9.8   4.3e-11   1.9e-07       4     108 ..      24     136 ..      21     141 .. 0.75
   2 !   16.2   0.2   8.5e-07    0.0038     135     248 ..     145     298 ..     138     302 .. 0.71
   3 !   37.5  17.2   2.9e-13   1.3e-09      13     179 ..     275     447 ..     260     491 .. 0.86

  Alignments for each domain:
  == domain 1  score: 30.3 bits;  conditional E-value: 4.3e-11
       MFS_1   4 aaflsalarsilgpalpl.alaedlg...ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll...fa..sslwlllvlrv 93 
                 +++l +++ ++ + +++  a ++ ++    + + + l++++y lg++++++++ + +d +Grr+++++g+ +++lg +++    f+   +l  ++v+r+
  EEA22471.1  24 GFLLFGYDQGVMSGIISDaAFNDVFTatkGNSTMQALVTAVYELGCLAGAIFALFRGDMIGRRWMIIIGASVMILG-VIIQvtaFPghVPLAQFMVGRI 121
                 56666666666666666555555555333466778899999***********************************.6666445544333336****** PP

       MFS_1  94 lqGlgagalfpagaa 108
                 ++G+g g+ ++++ +
  EEA22471.1 122 VTGIGNGMNTSTIPT 136
                 *****9998887765 PP

  == domain 2  score: 16.2 bits;  conditional E-value: 8.5e-07
       MFS_1 135 ilgpllgglla..sslg.....Wravfyilaivsllafvlfllllpeepperkrkspkeee....................kgtgpaplvp........ 198
                 ++g l++ ++   +++g     Wr +  +  ++++l +v ++ +lp++p+   + +++e++                    k     +lv         
  EEA22471.1 145 AIGTLIAYWIDygAHFGpsdlvWRFPIAFQVVFGILIIV-GMYYLPDSPRYLITRNKIEDGeyvlaaligheitdhetqiqK-----QLVLdsvrasga 237
                 677777777763344559999999999999999999877.669*****************9****99999999999654441.....333344554555 PP

       MFS_1 199 .....awkallkdpvl..w..illialllfffgfsg...lltllplylqevlglsglllagl 248
                       +k ll+  +   +  +l+ a+  +f  +sg   + ++lp++l + lg s   +a+l
  EEA22471.1 238 ldkdvRYKDLLTGGHTqhFrrMLIGASSQIFQQLSGcnaVIYYLPVLLEQSLGQS-TNQALL 298
                 445555666666665554255666666666655555999**************99.344443 PP

  == domain 3  score: 37.5 bits;  conditional E-value: 2.9e-13
       MFS_1  13 silgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa......ss.lw.lllvlrvlqGlgagalf 103
                 ++++  lp +l ++lg s  ++ l+ ++ ++ +av++ +  ++++++Grr+++l g ++ +++ ++++fa       +    +++ l + + +++++ +
  EEA22471.1 275 NAVIYYLPVLLEQSLGQSTNQALLIGGINMICYAVFATFSWFFIEKIGRRKLFLGGTFGQLAA-MIITFAclipnnKQvANgAVFGLFLYMCFFGATWL 372
                 556777888999***************************************************.77777556654411322256666667777778899 PP

       MFS_1 104 pagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepper 179
                 p+   + a+++p + r++a+++ + ++ l      ++ ++++ss+gWr +++++a++ + ++ +++l++pe+  ++
  EEA22471.1 373 PLPWLYPAEISPIKTRAKANAVSTCCNWLFNFTIVMITPVMVSSIGWR-TYLFFAVMNASFIPFIWLFYPETSGRS 447
                 ************************************************.99*********9888777777766554 PP

>> MFS_3  Transmembrane secretion effector
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   1.6   1.3e-05     0.056      28     130 ..      39     143 ..      32     148 .. 0.85
   2 ?   -2.6   0.3      0.29   1.3e+03     227     257 ..     329     359 ..     262     373 .. 0.47

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 1.3e-05
       MFS_3  28 iqevaasWlmtdisasplmvAlvqaaatLPifllsilaGalaDnfdrRkvllavqlllalvsvlltvlaalgllspwlllaltlligiGaaln...dPa 123
                 i + a   + t  +   +m Alv a   L  +  +i+a    D + rR++++++ ++++l+ v++ v+a+ g +     ++  +++giG  +n    P+
  EEA22471.1  39 ISDAAFNDVFTATKGNSTMQALVTAVYELGCLAGAIFALFRGDMIGRRWMIIIGASVMILG-VIIQVTAFPGHVPLAQFMVGRIVTGIGNGMNtstIPT 136
                 55666666788888889999************999999999**************999876.6788999***********99*******9986333699 PP

       MFS_3 124 WqAsvge 130
                 +qA  g 
  EEA22471.1 137 YQAECGT 143
                 9998775 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 0.29
       MFS_3 227 aalFglsasavlaLLPlvardqldgdalvyG 257
                 +  Fg  a+ +++   l+  ++  ++ +v+G
  EEA22471.1 329 GGTFGQLAAMIITFACLIPNNKQVANGAVFG 359
                 2223333333333333333333333333333 PP

>> DUF3792  Protein of unknown function (DUF3792)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   8.0     0.018        82      33     102 ..      53     122 ..      15     134 .. 0.79
   2 ?    9.5   6.0   0.00024       1.1      42     109 ..     303     369 ..     276     371 .. 0.75

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.018
     DUF3792  33 sekvlsililiililsvfigGflagkkakkkgllnGllvGllyflillllsllikksgsafslkllikll 102
                  ++++++l+++++ l++++g+++a  + +  g  + +++G+  +++ +++++ +  +   ++  ++ +++
  EEA22471.1  53 GNSTMQALVTAVYELGCLAGAIFALFRGDMIGRRWMIIIGASVMILGVIIQVTAFPGHVPLAQFMVGRIV 122
                 37899*************************************9999888887775555554444444444 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00024
     DUF3792  42 liililsvfigGflagkkakkkgllnGllvGllyflillllsllikksgsafslkllikllllllaga 109
                  +i+ + ++  ++++  k+++++l+ G+ +G l  +i + ++ li +++++++++ +  +l ++++ga
  EEA22471.1 303 NMICYAVFATFSWFFIEKIGRRKLFLGGTFGQLAAMI-ITFACLIPNNKQVANGAVFGLFLYMCFFGA 369
                 2333333456699999*****************9999.567777767777778888877777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (520 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       820  (0.045736); expected 358.6 (0.02)
Passed bias filter:                      440  (0.0245412); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.70u 0.30s 00:00:01.00 Elapsed: 00:00:00.49
# Mc/sec: 3162.49
//
Query:       EEA22472.1  [L=311]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.7e-34  117.5   0.0      9e-34  117.0   0.0    1.1  1  NmrA            NmrA-like family
    1.7e-15   57.4   0.0    3.2e-15   56.5   0.0    1.4  2  NAD_binding_10  NAD(P)H-binding
    1.4e-07   31.2   0.3    4.5e-07   29.6   0.3    2.0  1  Epimerase       NAD dependent epimerase/dehydratase family
    7.2e-05   22.3   0.1    0.00013   21.5   0.1    1.5  1  GDP_Man_Dehyd   GDP-mannose 4,6 dehydratase
  ------ inclusion threshold ------
      0.016   14.6   0.0      0.031   13.7   0.0    1.5  1  adh_short       short chain dehydrogenase
        0.1   13.2   0.1       0.47   11.1   0.1    2.0  1  F420_oxidored   NADP oxidoreductase coenzyme F420-dependent


Domain annotation for each model (and alignments):
>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.0   0.0     3e-37     9e-34       1     230 [.       8     245 ..       8     250 .. 0.87

  Alignments for each domain:
  == domain 1  score: 117.0 bits;  conditional E-value: 3e-37
                 EEESSTTSHHHHHHHHHHHHHT-EEEEEES-S-SHHHHHHHHSTTEEEES-TT-HHHHHHHHTT-SEEEE---GG..S-HHHHHHHHHHHHHHHS.-SE CS
        NmrA   1 IlviGaTGrqGksvvrallkaghkvralvRdtkselakslkeaGvelvkgdlddkeslvealkgvdvvfsvtgfy..skeiedgkklvdAakeaG.vkh 96 
                 I v+GaTG qG++v+r ll++g++v  + R+++s ++++lk+ G+++  g+ldd++ lv  +kg  + f+v++ +  ++ i++ +++ +Aak a+ ++h
  EEA22472.1   8 IFVTGATGCQGGAVARLLLSSGYTVHTISRNPNSRQSQHLKSLGANTFTGSLDDESALVVGMKGCIGLFLVIPPApyETTIKYTTTILAAAKSAKsIQH 106
                 78***********************************************************************8899********************** PP

                 EEEEE--..-GG.GT.SSS---TTTHH....HHHHHHHHHHCTS-E.EEEEE-EEGGG-BSSS-SS-BEEE-TTS.-EEEEESS-TTS-EE-HHHHHHH CS
        NmrA  97 fiySslg..ddndrsnaeepavphfds....Kaeieeyvralgipy.tfvyagffmenflsllaqlkvgdtappedkvtllgpgnpkavlldaeeDiGa 188
                 ++ S+    d  +r+ a +p+  + ++    K+  ee v a+g+ y +++++g fm nf ++     + ++++++  +  +    +   ++++e+D+++
  EEA22472.1 107 IVVSTTLgtDRPERMAAWDPNGGMLAMvikpKIAMEELVCAAGFKYhSILRPGNFMANFVAPKISVVNPELEKKG-VYPTSYTRAT-RIPMIDEADTAK 203
                 ****97511445677777888766653333399***********9769************988884444555544.3333333333.34447******* PP

                 HHHHHHHHHHHHTTEEEEE-SEEE-HHHHHHHHHHHHTS-EE CS
        NmrA 189 fvikilkdprklkgkriklagntlsgneivelfekkigktvk 230
                 f+++++ dp+ ++gk+i+l ++ ++++e+++ ++++ gk+++
  EEA22472.1 204 FTLAAFADPERFHGKAIALVSQLCTVDELMADLSRVFGKQIQ 245
                 ***************************************985 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.5   0.0   1.1e-18   3.2e-15       1     184 []      12     212 ..      12     212 .. 0.78
   2 ?   -3.8   0.0       3.3   9.9e+03      94     131 ..     221     254 ..     218     261 .. 0.55

  Alignments for each domain:
  == domain 1  score: 56.5 bits;  conditional E-value: 1.1e-18
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCH.HHHCTTTCEEEE--TT-CCHHHHHHTT-SEEEES-..--TCCHHHHHHHHHHHHHHCT.-- CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpekla.eleaeeglevvegdvtdvedlaealkgadaVvsal..ggggkdeegaknivdaakeag.vk 91 
                     GAtG  G ++++ ll++ g++v+ + Rnp++ + +  ++ g+++++g++ d+++l   +kg+   +  +  ++ +++ + + +i++aak a+ ++
      EEA22472.1  12 GATGCQGGAVARLLLSS-GYTVHTISRNPNSRQsQHLKSLGANTFTGSLDDESALVVGMKGCIGLFLVIppAPYETTIKYTTTILAAAKSAKsIQ 105
                     9****************.5*********975541444689*****************************54444445555*********97669* PP

                     EEEEEEETTTTSGCGCHHHHHHHH..CCHHHHHHHHHHHHHHHHSSSEE.EEEEE-CEE-ST.--SEEEEETTSS---............-EEEH CS
  NAD_binding_10  92 Rfvlvsaigvgdevpgefgewnke..llkaylaakraaeellrasgldw.TivrpggLtdep.ttkyrvvekgepfkg............gsisr 170
                     ++v+ +++g+++  p++   w+ +  +l+ +++ k a+eel+ a g+++  i+rpg ++ +  + k+ vv+ + + kg              i  
      EEA22472.1 106 HIVVSTTLGTDR--PERMAAWDPNggMLAMVIKPKIAMEELVCAAGFKYhSILRPGNFMANFvAPKISVVNPELEKKGvyptsytratriPMIDE 198
                     *********996..7777788776669*********************978******98885477777775444333222211222212246777 PP

                     HHHHHHHHHHCTXG CS
  NAD_binding_10 171 adVAdvlvavlddp 184
                     ad A++ +a+++dp
      EEA22472.1 199 ADTAKFTLAAFADP 212
                     88888877777765 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 3.3
                     EEEEETTTTSGCGCHHHHHHHHCCHHHHHHHHHHHHHH CS
  NAD_binding_10  94 vlvsaigvgdevpgefgewnkellkaylaakraaeell 131
                      lvs +++ de + +++++    +++ ++ ++ ++ ++
      EEA22472.1 221 ALVSQLCTVDELMADLSRV----FGKQIQTHYLSDVEI 254
                     6677777776666555554....444444444444444 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.6   0.3   1.5e-10   4.5e-07       1      56 [.       8      65 ..       8     192 .. 0.88

  Alignments for each domain:
  == domain 1  score: 29.6 bits;  conditional E-value: 1.5e-10
                EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC..EEEE--TT-HHHH CS
   Epimerase  1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl..elveldltdrsal 56
                i+VtGatG+ G a+++ ll+ gy+v++++r+++++++++l+ l  +  ++ l d+sal
  EEA22472.1  8 IFVTGATGCQGGAVARLLLSSGYTVHTISRNPNSRQSQHLKSLgaNTFTGSLDDESAL 65
                89*****************************999999988887888888888887776 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.1   4.3e-08   0.00013       1      45 [.       9      53 ..       9      77 .. 0.89

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 4.3e-08
                   EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT CS
  GDP_Man_Dehyd  1 LiTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakd 45
                   ++TG +G  G  +a+lLl+ gy+vh i r+ +s + +++++l  +
     EEA22472.1  9 FVTGATGCQGGAVARLLLSSGYTVHTISRNPNSRQSQHLKSLGAN 53
                   59*****************************99999999888654 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0     1e-05     0.031       2      49 ..       7      52 ..       6      78 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1e-05
                EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTS CS
   adh_short  2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkeega 49
                +++vtGa++  G a+a+ l+++G++v  ++r+++      ++lk++ga
  EEA22472.1  7 TIFVTGATGCQGGAVARLLLSSGYTVHTISRNPNSR--QSQHLKSLGA 52
                799**************************9998866..4555555543 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.1   0.00016      0.47       7      55 ..      14      59 ..       8     114 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00016
                   TSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHH.HHHC-EEECECH CS
  F420_oxidored  7 aGnmgealasgllaagaqpheivvansrnpekaeela.eelgvkvtavdn 55
                   +G +g a+a+ ll++g   + +  + srnp+++++ + ++lg+++++++ 
     EEA22472.1 14 TGCQGGAVARLLLSSG---YTVHTI-SRNPNSRQSQHlKSLGANTFTGSL 59
                   899*************...999966.999999888775777766665443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (311 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       464  (0.0258799); expected 358.6 (0.02)
Passed bias filter:                      440  (0.0245412); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2206.32
//
Query:       EEA22473.1  [L=430]
Description: C6 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-07   30.3   7.3    5.9e-07   29.5   7.3    1.4  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.5   7.3   3.3e-11   5.9e-07       1      35 [.      22      55 ..      22      60 .. 0.93

  Alignments for each domain:
  == domain 1  score: 29.5 bits;  conditional E-value: 3.3e-11
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCT CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfyse 35
                ++C  C k K++Cd   P+Cs+C +++l+C+ y+ 
  EEA22473.1 22 KSCRACAKAKRRCDLILPVCSRCSQRRLNCE-YPL 55
                59*****************************.875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (430 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       530  (0.029561); expected 358.6 (0.02)
Passed bias filter:                      360  (0.0200792); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2979.44
//
Query:       EEA22474.1  [L=518]
Description: hypothetical protein PMAA_091030 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
      0.014   15.5   0.1      0.061   13.4   0.1    2.2  2  DNA_primase_S  DNA primase small subunit


Domain annotation for each model (and alignments):
>> DNA_primase_S  DNA primase small subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.1   3.4e-06     0.061      34     119 ..     155     231 ..     148     392 .. 0.82
   2 ?   -0.9   0.0     0.083   1.5e+03      87     105 ..     450     469 ..     411     504 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 3.4e-06
                    HH-----GGGEEEEE--SEE.EEEEE--TTEEES-HHHHHHHHH.H..................................HCHHHHCT CS
  DNA_primase_S  34 llredfgfkdilwvfsgrrG.fHcwvsdkdarpltdeeraaivn.ylnlyrplhpflsrsmlkivkpvveeiileeqdpfeikkllrl 119
                      + ++g+++++++ sg  G +H+w sd +ar + ++   + ++  +++ r++h+ l+ +  + +++++ ++        +  k +++
     EEA22474.1 155 QTKNHYGKNEAHYYVSGL-GrYHLWDSDPKARKMYNRCTYEAKEpVFTVPREKHDLLVDR--RQFYNKKLTK--------KETKNTTQ 231
                    556889***********7.55***********************9999999999999886..5555544444........33333333 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.083
                    .................... CS
  DNA_primase_S  87 flsrs.mlkivkpvveeiil 105
                    +++rs +++i+++v++++  
     EEA22474.1 450 IINRSrICNILREVKDSMFE 469
                    68899999999999998854 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (518 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       800  (0.0446204); expected 358.6 (0.02)
Passed bias filter:                      582  (0.0324614); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.66u 0.31s 00:00:00.97 Elapsed: 00:00:00.52
# Mc/sec: 3018.40
//
Query:       EEA22475.1  [L=347]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (347 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       636  (0.0354733); expected 358.6 (0.02)
Passed bias filter:                      223  (0.0124379); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 2265.35
//
Query:       EEA22476.1  [L=694]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.6e-38  130.3   0.3    8.6e-38  130.3   0.3    1.6  2  RVT_2     Reverse transcriptase (RNA-dependent DNA polymerase
  ------ inclusion threshold ------
      0.014   14.9   0.0      0.024   14.1   0.0    1.3  1  RVT_1     Reverse transcriptase (RNA-dependent DNA polymerase
      0.032   14.1   0.0      0.072   13.0   0.0    1.6  1  Flg_hook  Flagellar hook-length control protein FliK


Domain annotation for each model (and alignments):
>> RVT_2  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  130.3   0.3   1.4e-41   8.6e-38       9     234 ..     198     420 ..     188     426 .. 0.91
   2 ?   -3.3   0.1      0.97   5.8e+03      15      61 ..     615     663 ..     611     666 .. 0.71

  Alignments for each domain:
  == domain 1  score: 130.3 bits;  conditional E-value: 1.4e-41
       RVT_2   9 PkdrkaigsrWvftkkkddl.kevkykarlvaqGfsqkagedydevfaPvirldsvrLllalaaeeelvvhqldvdsafLnaeldeevyvkqPpGfeid 106
                  k+++ +   W++  k+d++ + vk karlv++G  q    d  +++a  +   s r ++a+aa  +l + q d   af+na+ldee++++  pG+   
  EEA22476.1 198 AKGKQILDCMWIYVYKQDKKgRLVKCKARLVVRG-DQEKRDDMRDTYAATLAARSFRTFMAIAARFDLELKQYDAVNAFVNAKLDEEIFMRMAPGYR-- 293
                 577888999********999899***********.577889******************************************************96.. PP

       RVT_2 107 reeekvykLnkslyGlkqapllWnekidkvLkklgferseaesGlyvrgtgegklivalyvddlliagsdikiled..vkkelakkfklkdlgkvskfL 203
                  e++k+y+Lnk+lyGl+++pllW++++++++ klgf+  + e    +++     +++  yvdd+++a ++++ le   + ++l +k++++   +++ fL
  EEA22476.1 294 -ESGKIYQLNKALYGLRRSPLLWQKELTSTFIKLGFKAVPHEPCCMLKS----GVMLFFYVDDIVVAYKKSRQLEAnlILNQLRAKYNISGGEDLEWFL 387
                 .46****************************************999999....78999**********9999886533889****************** PP

       RVT_2 204 Gieiaq..eaggiklsladyiakvvkkfeltda 234
                 G+ i++  ++  i ls+a yi k++k ++ ++a
  EEA22476.1 388 GMRIIRdrSNKMIWLSQATYIDKIAKLADTQQA 420
                 ****986568889***********998876655 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 0.97
       RVT_2  15 igsrWvftkkkddlkevkyk..arlvaqGfsqkagedydevfaPvirld 61 
                 i ++Wv +  ++  ++v+y     ++a+G ++  + + +++f   ir+d
  EEA22476.1 615 IHNHWVRQEVQNGDVQVHYMptKDMIANGLTKALNRQEHHIFLKQIRVD 663
                 7789999999888889988522457888888877777667766666665 PP

>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   4.1e-06     0.024     117     184 ..     287     366 ..     257     378 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 4.1e-06
                 .........TEEEEESB--ST-TTHHHHHHHHHHHHHTT-T................TEEECTTEEEEEESSHHHHHHHH CS
       RVT_1 117 rv.nge.eskgryekkglpqGsvlSPllfnlfmnellrelrkra..........kgvtllrYaDDililskskeelqell 184
                 r+  g  es+++y+ +    G+  SPll++  +++ + +l  +a          +gv l  Y+DDi++++k+  +l++ l
  EEA22476.1 287 RMaPGYrESGKIYQLNKALYGLRRSPLLWQKELTSTFIKLGFKAvphepccmlkSGVMLFFYVDDIVVAYKKSRQLEANL 366
                 4434445789999999999************999999999988899**************************99977654 PP

>> Flg_hook  Flagellar hook-length control protein FliK
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   1.2e-05     0.072      33      69 ..     579     615 ..     572     632 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 1.2e-05
                 EETTEEEEEEEE-SCHHHHHHHHTHHHHHHHHHCCTT CS
    Flg_hook  33 lrggqlsvqltaenpetrelLeqnlprLreaLaaaGl 69 
                 +r +  ++++  +n++t+ lLe+++prLr+ L+   +
  EEA22476.1 579 IRFQTPTLHVYCDNQQTLGLLEKDAPRLRTKLRHVDI 615
                 555566899***********************87444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (694 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       368  (0.0205254); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.47
# Mc/sec: 4463.14
//
Query:       EEA22477.1  [L=255]
Description: hypothetical protein PMAA_091060 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.29   10.9   5.9       0.37   10.6   0.3    2.4  2  Nsp1_C    Nsp1-like C-terminal region


Domain annotation for each model (and alignments):
>> Nsp1_C  Nsp1-like C-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.9    0.0056     1e+02       3      65 ..     101     164 ..      99     184 .. 0.81
   2 ?   10.6   0.3   2.1e-05      0.37      18      50 ..     211     243 ..     192     248 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.0056
      Nsp1_C   3 aktveiapsaas.lknktldelinkWtteLeeqekeFeeqakkvneWDrvLvengekIskLyse 65 
                 ++tv++++++ s     +ld  i+ ++  L+ +++ + e +++ ++ +++ +   + +s  y++
  EEA22477.1 101 QETVQAETMNRStHADGELDRAIKMFNVRLNLYKQRYFEWSEQKKAIEQIFIWMKQTVSPSYHK 164
                 677888888888788899*******************999999888888777666666655555 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 2.1e-05
      Nsp1_C  18 ktldelinkWtteLeeqekeFeeqakkvneWDr 50 
                   l+  i kW++ L e+e++F   a++v +W  
  EEA22477.1 211 RDLEAWIIKWEELLLEAERKFMVIADDVLDWST 243
                 67999**************************75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (255 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       881  (0.0491383); expected 358.6 (0.02)
Passed bias filter:                      495  (0.0276089); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 1733.80
//
Query:       EEA22478.1  [L=533]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.2e-51  173.8   0.0    9.2e-51  171.8   0.0    1.9  2  DUF1989          Domain of unknown function (DUF1989)
    3.2e-16   59.4   0.0    6.3e-16   58.4   0.0    1.5  1  Polysacc_deac_1  Polysaccharide deacetylase
    6.5e-07   29.2   0.1    1.1e-06   28.4   0.1    1.5  1  DUF2334          Uncharacterized protein conserved in bacteri
  ------ inclusion threshold ------
      0.082   11.2   0.0       0.11   10.8   0.0    1.1  1  DUF2194          Uncharacterised protein conserved in bacteri


Domain annotation for each model (and alignments):
>> DUF1989  Domain of unknown function (DUF1989)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  171.8   0.0     2e-54   9.2e-51       3     167 .]       4     172 ..       3     172 .. 0.96
   2 ?   -1.4   0.0      0.34   1.5e+03      86     135 ..     244     288 ..     215     304 .. 0.77

  Alignments for each domain:
  == domain 1  score: 171.8 bits;  conditional E-value: 2e-54
     DUF1989   3 iparsgravevkaGqvlriidleGkqvvdllafnaddprerlsaadTrklqgsahlttgdrlysnlgrplltiveDtv.grHDtlggacdaevnellyg 100
                 +par++ a++++aGq+++ii+++Gkqvvd++afn++dpr+ ls+ +Tr++ +++ ++ gd+lys++++p+lti eDt+ g+HD+++ +cdae+++++  
  EEA22478.1   4 LPARKAVALQISAGQAIKIINTHGKQVVDFWAFNPSDPRDFLSMVHTRTVLRKVAVRLGDSLYSTRRKPMLTIEEDTTkGVHDIIWSTCDAERYRMQGV 102
                 79****************************************************************************99****************994 PP

     DUF1989 101 egkeyhrnCrdnllralak.....yglterdvpdvlNlFmnvgvdedgrlfmeespskpGdyvelraemDll 167
                   + yh+nC++n+++al+       g+  ++vpd++N Fmnv++d++g l+++e++s++G+y++lr + Dl+
  EEA22478.1 103 --QGYHDNCSENMHTALKTgfpdwAGIPDNWVPDPFNTFMNVAIDHHGGLDIREPTSEKGQYIVLRSNADLI 172
                 ..56*************8455567899*******************************************96 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.34
     DUF1989  86 lggacdaevnellygegkeyhrnCrdnllralakyglterdvpdvlNlFm 135
                 lg+ c+++ n + y+   ++ ++++   +r l    l+++d++d + +F 
  EEA22478.1 244 LGTGCHPDNNMADYS---SGVFAGQIGAIRLL--NMLKKFDIADKVTWFV 288
                 788888888888883...45555555555555..4567778888888885 PP

>> Polysacc_deac_1  Polysaccharide deacetylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.4   0.0   1.4e-19   6.3e-16      23     123 ..     270     372 ..     225     373 .. 0.92

  Alignments for each domain:
  == domain 1  score: 58.4 bits;  conditional E-value: 1.4e-19
                      HHHHHHHHCT-..-EEEEE-HHHHCH-HHHHHHHHHTTEEEEE--SS--EGGGSHHHHHHHHHHHHHHHHHHHHS----EEE-GGGEE-HHHHH CS
  Polysacc_deac_1  23 eilpvLkkykv..katffvigglvedypdevremaasGveignHtinhsnlkrlseeevrreierakdalrkalgreprlfryPygsasatvle 114
                      ++l++Lkk ++  k t+fv g+++e+ p+ v+++++sG eig H++ h+ + +++ +++r+ +e++ ++  k +g+ pr +r+P   + +t++e
       EEA22478.1 270 RLLNMLKKFDIadKVTWFVPGHTMETFPETVQQVVKSGAEIGLHGYAHEGIYQMTVDQERDVLEKCIEVATKLCGKAPRGYRAPMYTIRETTVE 363
                      899********999******************************************************************************** PP

                      HHHHTT.EE CS
  Polysacc_deac_1 115 varelgfay 123
                      ++r++ f y
       EEA22478.1 364 MLRKHKFLY 372
                      *****9977 PP

>> DUF2334  Uncharacterized protein conserved in bacteria (DUF2334)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.4   0.1   2.5e-10   1.1e-06      55     147 ..     294     376 ..     284     503 .. 0.74

  Alignments for each domain:
  == domain 1  score: 28.4 bits;  conditional E-value: 2.5e-10
     DUF2334  55 pefvevLkylqakGgeialHGYtHqygtvksevsgegfeflseseakeriekGieilkkl.gikpkgFeaPhyaaseetykalkkyfsiiyer.y 147
                 + f e+++++ + G+ei+lHGY H+            ++ ++ ++ ++ +ek ie+++kl g  p+g+ aP y++ e+t ++l+k+ +++y++ +
  EEA22478.1 294 ETFPETVQQVVKSGAEIGLHGYAHEGI----------YQ-MTVDQERDVLEKCIEVATKLcGKAPRGYRAPMYTIRETTVEMLRKH-KFLYDTsL 376
                 56889999****************997..........33.46888899********9996257*********************55.55666642 PP

>> DUF2194  Uncharacterised protein conserved in bacteria (DUF2194)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   2.4e-05      0.11     449     478 ..     299     328 ..     277     368 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 2.4e-05
     DUF2194 449 alkellksegelGiHGYNHqsltkenWkne 478
                 ++++++ks+ e+G+HGY H  + + +  +e
  EEA22478.1 299 TVQQVVKSGAEIGLHGYAHEGIYQMTVDQE 328
                 6899***************98877665444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (533 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       499  (0.027832); expected 358.6 (0.02)
Passed bias filter:                      472  (0.0263261); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 3409.59
//
Query:       EEA22479.1  [L=573]
Description: 2,4-dichlorophenol 6-monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.1e-62  210.2   0.0    6.2e-62  209.9   0.0    1.1  1  FAD_binding_3   FAD binding domain
    1.2e-08   34.9   0.1    1.3e-07   31.6   0.0    2.3  3  DAO             FAD dependent oxidoreductase
    1.4e-07   31.7   0.0    6.8e-06   26.2   0.0    2.7  2  Phe_hydrox_dim  Phenol hydroxylase, C-terminal dimerisation d
    7.4e-06   25.3   0.1    1.9e-05   23.9   0.0    1.6  2  FAD_binding_2   FAD binding domain
    4.1e-05   22.9   0.0    7.7e-05   22.0   0.0    1.3  1  Thi4            Thi4 family
    0.00011   21.0   0.0    0.00021   20.1   0.0    1.4  1  HI0933_like     HI0933-like protein
     0.0002   20.7   0.1     0.0021   17.3   0.0    2.2  2  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
     0.0002   21.5   0.1    0.00073   19.7   0.1    2.0  1  NAD_binding_8   NAD(P)-binding Rossmann-like domain
    0.00021   20.8   0.1    0.00031   20.2   0.1    1.2  1  FAD_oxidored    FAD dependent oxidoreductase
     0.0011   18.4   0.0     0.0017   17.7   0.0    1.3  1  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
     0.0011   17.9   0.0     0.0045   15.9   0.0    1.8  2  Trp_halogenase  Tryptophan halogenase
     0.0014   17.8   0.0      0.002   17.3   0.0    1.2  1  Lycopene_cycl   Lycopene cyclase protein
     0.0086   16.6   0.0       0.02   15.4   0.0    1.6  1  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
  ------ inclusion threshold ------
      0.014   14.5   0.0      0.025   13.7   0.0    1.4  1  GIDA            Glucose inhibited division protein A
      0.097   13.1   0.0       0.18   12.3   0.0    1.4  1  NAD_binding_7   Putative NAD(P)-binding
       0.18   11.7   0.0        0.3   11.0   0.0    1.4  1  3HCDH_N         3-hydroxyacyl-CoA dehydrogenase, NAD binding 


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  209.9   0.0   5.5e-65   6.2e-62       2     347 ..      11     367 ..      10     369 .. 0.87

  Alignments for each domain:
  == domain 1  score: 209.9 bits;  conditional E-value: 5.5e-65
                    EEEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSS..S--EEEHHHHHHHHHTT-HHHHHHHSEECCCCEEEEEEE.CCCC....CEEEEEH CS
  FAD_binding_3   2 tdVlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlp..radglnqrtmellrqlGledrilaegapnelmgealyne.lsdt....pkaradl 90 
                    +dV+IVG+Gp+Gl++a   ++ G +v+++ek+++++++   ra  l +rt+e l+ql l + +l++g   +  + ++y++ ++++       ++++
     EEA22479.1  11 YDVVIVGGGPVGLLTAYQIARFGLSVCVLEKYDKQTQDAfgRAIALFPRTLEQLDQLDLIEPMLQKG--FACRTSVTYKDgVQQIpgrvWTFMENI 104
                    79**********************************99888**************************..555566777664333354346666666 PP

                    HCHHCST-CEE--HHHHHHHHHHHHHHHTEEETCSEEEECCE.......ECCCCCCCEEEECCTTEEEEEEEEEEEE--GTT-HHHHHHTGGEEEE CS
  FAD_binding_3  91 elesspervtvypqteleriLvehaeerglqvrfktevesle.......qdeegvtaevrdketgeeetvrakYlvGaDGgrStvrktlgiefege 179
                    + ++    v v+ q  +e iL+e++++ g+  r++te +++e        d   v++ +++ +t+e+  +r+kYlvGaDGgrS vr+ ++i+feg 
     EEA22479.1 105 K-DTAFDFVLVLRQMHTEDILREKLRSVGAVYRESTECTGFEiedgvtsSDAYPVKSFFTNTKTQEKIVLRSKYLVGADGGRSFVRRHADIPFEGD 199
                    6.9**********************************8888722222124555566666699999999**************************** PP

                    EEEEEEEEEEEEEEC-SCCCTTCCEEEEECCTTEEEEEECCETEEEEEEEEECCE-GGGSCCCHHHHHHHHHHHHHHTTSSCEE.EEEEEEEEEEE CS
  FAD_binding_3 180 etvyeagvldvlfdadlsdiveplvlilsaesrgvmviPlentlerfyvqvearaekeersekfteeevkarlreivgektldv.eieevsawtva 274
                    ++  ++  +d ++++d++ i     +i s+  + v   Pl+     ++ ++ +++ +++ +  +tee++++++ e++ +  ++  e+ + + +t++
     EEA22479.1 200 SSEDKWIRIDGMVETDMP-IKRSYGAIESKTHGNVLWAPLDH-GATRIGYAFTSEIAAKYPGGVTEEVAVKEAIESMRPFNVKFtEVHWWTLYTIG 293
                    *99999999999999999.44445777777777789999999.55567888888888888*************999999999988*********** PP

                    EEEESSSE.ETTEEE-GGGTEEE-STTSHHHHHHHHHHHHHHHHHHHHHTTSS-GGGGHHHHHHHHHHHHHHHH CS
  FAD_binding_3 275 qrvaekyr.kgrvflaGDAaHihpPtgGqGlNtaiqDavnLawkLaavlkGeAkeelLdtYeeerravaqavvd 347
                    qr+a++++ k+r+fl GDAaH+h+  ++qGlNt+i D+vnLawkLa+ + G   +++L+tY +err  ++++++
     EEA22479.1 294 QRIARDFStKDRIFLCGDAAHTHSSGAAQGLNTGIHDSVNLAWKLASQIHGFTHPDVLQTYATERRTAVEKLIN 367
                    *******7367**********************************************************99985 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.6   0.0   1.1e-10   1.3e-07       1      49 [.      12      62 ..      12      82 .. 0.83
   2 ?   -0.3   0.0      0.55   6.2e+02     152     177 ..     124     153 ..     111     198 .. 0.71
   3 ?   -2.7   0.0       3.1   3.5e+03      31      65 ..     312     343 ..     296     377 .. 0.66

  Alignments for each domain:
  == domain 1  score: 31.6 bits;  conditional E-value: 1.1e-10
                EEEEECTSHHHHHHHHHHHHTT..EEEEESSSSTTSSGGGSSEEEEESSSS CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..VtllekgdiagsgaSgrnsgllhsglr 49
                dvvi+GGG +Gl tAy+ ar g  V++lek d   + a gr+ +l+   l+
  EEA22479.1 12 DVVIVGGGPVGLLTAYQIARFGlsVCVLEKYDKQTQDAFGRAIALFPRTLE 62
                9*****************999**********98888999998877766554 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.55
                 HHHHHHHTT-EEEESECEEEEEEEE....T CS
         DAO 152 laraaealGveilegtevtgleeed....g 177
                 l++++++ G+  +e te tg+e ed     
  EEA22479.1 124 LREKLRSVGAVYRESTECTGFEIEDgvtsS 153
                 56789999*************887633333 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 3.1
                 STTSSGGGSSEEEEESSSSTHHSTHHHHHHHHHHH CS
         DAO  31 iagsgaSgrnsgllhsglrylpeaselarlsleal 65 
                  a++++Sg+++gl ++ +++  +    ++l+ + +
  EEA22479.1 312 AAHTHSSGAAQGLNTG-IHDSVN--LAWKLASQIH 343
                 3445777777777666.543442..3456666655 PP

>> Phe_hydrox_dim  Phenol hydroxylase, C-terminal dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.2   0.0     6e-09   6.8e-06       1      93 [.     406     493 ..     406     500 .. 0.90
   2 ?    2.4   0.0      0.13   1.5e+02     149     166 .]     523     541 ..     511     541 .. 0.79

  Alignments for each domain:
  == domain 1  score: 26.2 bits;  conditional E-value: 6e-09
  Phe_hydrox_dim   1 FtsGvgveYqpsllvaevkskqnlatglrpGrrlpsakVvrvaDanpvdlqdeipsdGrfRilvfagdlsdaeqksrlsaladalsskesfls 93 
                     F +G+g++Y++++l   ++  ++ + +++pG+r   ++++     + v++ +  +  G+f i+vfag+++++  k +l+al ++l++++ ++s
      EEA22479.1 406 FNTGLGINYPANVL---NQFPSDTSLKIEPGNRAIDVDLTVPGINRKVRFYEIARNLGKFWIVVFAGKIEST--KPSLEALRNYLADEKGLYS 493
                     889***********...5667788889*****************************************9988..799********87765554 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.13
  Phe_hydrox_dim 149 yhe.dgaaYekyGidkkrG 166
                     y + dg a+ekyGid++ G
      EEA22479.1 523 YYDiDGLAHEKYGIDPSVG 541
                     4454678********9866 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.0   1.7e-08   1.9e-05       1      49 [.      12      57 ..      12      78 .. 0.83
   2 ?   -3.6   0.0       3.8   4.3e+03      41      99 ..     317     368 ..     313     377 .. 0.72

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 1.7e-08
                   SEEEE--SHHHHHHHHHHHHTTT-EEEEESSSGGGSGGGG--S-EE-TT CS
  FAD_binding_2  1 DviViGsGlAGLaAAleaaeaGlkvavvekeqefggatawsqGgidavl 49
                   Dv+++G+G  GL  A+++a+ Gl+v+v+ek ++   +t+ ++G + a+ 
     EEA22479.1 12 DVVIVGGGPVGLLTAYQIARFGLSVCVLEKYDK---QTQDAFGRAIALF 57
                   9*******************************9...7777777655554 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 3.8
                    --S-EE-TT..SSGGSTC.CHHHHHHHHHHHHTTT-S-HHHHHHHHHTHHHHHHHHHHT CS
  FAD_binding_2  41 sqGgidavlspeqkkagikdspelhrtdtlkaldeladqplveafveaapeavdeLeel 99 
                    s+G ++ ++       gi ds+ l+ + + ++ ++  ++++ ++++++ + av+ L ++
     EEA22479.1 317 SSGAAQGLN------TGIHDSVNLA-WKLASQIHGFTHPDVLQTYATERRTAVEKLINY 368
                    566666666......6776755555.456677777788999999999999999888765 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.0   0.0   6.9e-08   7.7e-05      18      49 ..      11      41 ..       5      46 .. 0.94

  Alignments for each domain:
  == domain 1  score: 22.0 bits;  conditional E-value: 6.9e-08
                EEEEEE--SHHHHHHHHHHHHCTTS-EEEEES CS
        Thi4 18 sDvvivGaGssGLtaayylakkpdlkvailer 49
                 DvvivG+G+ GL +ay +a+  +l v++le+
  EEA22479.1 11 YDVVIVGGGPVGLLTAYQIARF-GLSVCVLEK 41
                5********************9.*******97 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.1   0.0   1.9e-07   0.00021       1      34 [.      11      44 ..      11      49 .. 0.93

  Alignments for each domain:
  == domain 1  score: 20.1 bits;  conditional E-value: 1.9e-07
                 -SEEEE--SHHHHHHHHHHHHTT--EEEE-SSSS CS
  HI0933_like  1 kdviviGgGaAGlmaAisaakrgkrVlllekakk 34
                 +dv+++GgG+ Gl++A ++a+ g +V +lek +k
   EEA22479.1 11 YDVVIVGGGPVGLLTAYQIARFGLSVCVLEKYDK 44
                 59****************************9876 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0   1.9e-06    0.0021       2      35 ..      12      49 ..      11     209 .. 0.72
   2 ?    0.6   0.0      0.23   2.6e+02     267     278 ..     302     313 ..     293     330 .. 0.78

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 1.9e-06
                 SEEEE--SHHHHHHHHHHHHHTS-EEEEE....TTHCH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxx RF
  Pyr_redox_2  2 dvvviGgGpAGlaaaltlaqagakvtlve....legtc 35
                 dvv++GgGp Gl +a ++a+ g+ v ++e    +++  
   EEA22479.1 12 DVVIVGGGPVGLLTAYQIARFGLSVCVLEkydkQTQDA 49
                 67777777777777777777777777765554333333 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.23
                  SSTTEEE-GGGC CS
                  xxxxxxxxxxxx RF
  Pyr_redox_2 267 nvpgiyaiGDva 278
                  + + i+++GD a
   EEA22479.1 302 TKDRIFLCGDAA 313
                  4799******99 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.1   6.6e-07   0.00073       1      28 [.      15      42 ..      15      46 .. 0.95

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 6.6e-07
                   EE--SHHHHHHHHHHHCCTEEEEEE-SS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekr 28
                   IvG+G  Gl++Ay +a+ g++v +lek 
     EEA22479.1 15 IVGGGPVGLLTAYQIARFGLSVCVLEKY 42
                   9*************************95 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.1   2.8e-07   0.00031       1      32 [.      12      43 ..      12      44 .. 0.97

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 2.8e-07
  FAD_oxidored  1 DvvVvGGgpaGvaAAiaAaraGakvlLveerg 32
                  Dvv+vGGgp G+  A++ ar G +v+++e+++
    EEA22479.1 12 DVVIVGGGPVGLLTAYQIARFGLSVCVLEKYD 43
                  9****************************986 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0   1.5e-06    0.0017       1      30 [.      14      42 ..      14      64 .. 0.91

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 1.5e-06
  Pyr_redox_3  1 iIiGaGPaGlaaaielkkagledylilEkg 30
                 +I+G+GP Gl +a+++ ++gl ++++lEk 
   EEA22479.1 14 VIVGGGPVGLLTAYQIARFGL-SVCVLEKY 42
                 7********************.7*****95 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0     4e-06    0.0045       1      79 [.      12      88 ..      12     121 .. 0.84
   2 ?   -0.6   0.0      0.41   4.6e+02     256     291 ..     230     273 ..     146     283 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 4e-06
                    EEEEE--SHHHHHHHHHHHHHTTTSSEEEEEE-SSS---.SS-E..E--THHHHTHHHHT--HHHHCHHCT-EEE-EEEEES CS
  Trp_halogenase  1 kivivGGGtaGwlaAaalakalkgklevtlveseeigtv.gvGe..atipsirkllrlLgideeeflreteatfKlgikFed 79
                    ++vivGGG+ G l+A  +a+ +   l+v ++e+ +  t    G+  a+ p + + l++L++ e   + +  ++++ +++++d
      EEA22479.1 12 DVVIVGGGPVGLLTAYQIARFG---LSVCVLEKYDKQTQdAFGRaiALFPRTLEQLDQLDLIEP--MLQKGFACRTSVTYKD 88
                    69********************...99*****977666515788668999999999*****999..8888888888888876 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.41
                     SEEEEEEEETTEEEE.EEEE-TTTS.......-HHHHHHHHHHH CS
  Trp_halogenase 256 aGWtWkiPLqhrlgn.Gyvyssaha.......dddeAlaellae 291
                     +G +   PL h ++  Gy++ s+ a       +++ A++e ++ 
      EEA22479.1 230 HGNVLWAPLDHGATRiGYAFTSEIAakypggvTEEVAVKEAIES 273
                     55555579***99999******9998888888888888777665 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0   1.7e-06     0.002       1      34 [.      12      43 ..      12      49 .. 0.92

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 1.7e-06
  Lycopene_cycl  1 DvvviGaGpAglslAarlteakpglkvvlieasp 34
                   Dvv++G+Gp gl+ A ++  a+ gl+v+++e  +
     EEA22479.1 12 DVVIVGGGPVGLLTAYQI--ARFGLSVCVLEKYD 43
                   9*****************..**********9765 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   1.8e-05      0.02       2      41 ..      13      53 ..      12      58 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 1.8e-05
                EEEECSSHHHHHHHHHHHHTTSEEEEEESSSSSS.TTSSHH CS
   Pyr_redox  2 vvvvGgGyiglElAgalaelgkkVtvversdkll.rllDee 41
                vv+vGgG +gl  A  +a++g +V v+e  dk    +++++
  EEA22479.1 13 VVIVGGGPVGLLTAYQIARFGLSVCVLEKYDKQTqDAFGRA 53
                8***************************9998776666655 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   2.2e-05     0.025       1      29 [.      12      44 ..      12      54 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 2.2e-05
                CEEEE-SSHHHHHHHHHHHHTT--EEEE....E CS
        GIDA  1 dviViGgGhAGceAAlaaarlGakvlLi....t 29
                dv+++GgG  G+  A+++ar G++v  +     
  EEA22479.1 12 DVVIVGGGPVGLLTAYQIARFGLSVCVLekydK 44
                79***********************99844432 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   0.00016      0.18       9      44 ..      12      46 ..       8     114 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00016
  NAD_binding_7  9 kvlvvGgGevAarkvrklleagakvtvvapevkeel 44
                    v++vGgG+v++  +++++++g  v v+ +   +++
     EEA22479.1 12 DVVIVGGGPVGLLTAYQIARFGLSVCVLEKYD-KQT 46
                   69*************************98873.333 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00027       0.3       2      44 ..      13      55 ..      12     106 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00027
                EEEE--SCCHHHHHHHHHHTT-EEEEE-S-HHHHHHHHHHHHH CS
     3HCDH_N  2 vaviGaGtmGagiaavfasagleVvlvdiseealekalekiek 44
                v ++G G +G   a+++a+ gl+V +++  +++ ++a  ++ +
  EEA22479.1 13 VVIVGGGPVGLLTAYQIARFGLSVCVLEKYDKQTQDAFGRAIA 55
                89***************************88888777666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (573 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       365  (0.0203581); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              16  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.41
# Mc/sec: 4195.41
//
Query:       EEA22480.1  [L=649]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      6e-15   55.0   3.6    9.2e-15   54.4   3.6    1.3  1  Fungal_trans   Fungal specific transcription factor domain
  ------ inclusion threshold ------
      0.021   14.9   0.3      0.042   13.9   0.3    1.4  1  Duffy_binding  Duffy binding domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.4   3.6     1e-18   9.2e-15       1     267 []     279     529 ..     279     529 .. 0.79

  Alignments for each domain:
  == domain 1  score: 54.4 bits;  conditional E-value: 1e-18
  Fungal_trans   1 ldrffsnfhpqfpilhkpsflpktssenssksayasplll.lailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqs 96 
                   l+++ + +hp fpil   +f++       ++ +   p+ +  a++al+a+f+  ++  s  +   ++    ++ l   ++ h++++  s+ l +l s
    EEA22480.1 279 LKLYIKFVHPRFPILSLSDFSRMP----FPECNVLYPIGIqSAVYALAAPFTCWDDELSVLKGY-VQ--ISTQDLW--AIAHRSYQRASC-LSHLSS 365
                   789**************9999988....4444444455557***********999988733333.22..2222222..233788888888.888888 PP

  Fungal_trans  97 Llllelyektssdralher......hhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPc 187
                   L l+ l +++   ++++        +++ a+++a slgL+ +ps++       l+ +e+  rrRlww++++  ++ a++  rp +l+d++ +++   
    EEA22480.1 366 LQLCLLLLQMPPPNYAVAEplstwaLSCSALSMAESLGLNLDPSDWR------LPLKEIMLRRRLWWYTYMQHVWQAMVIARPLHLNDDSWDVSPLT 456
                   8666666666665455444477777********************99......****************************************9444 PP

  Fungal_trans 188 ddddlwesddaseetlvetklsneeksrkiasfllaLkkilskiagsllsiekqlqqrdlqseklswveeleraldnWre 267
                     d+++   +++e++           +    ++++ L+ i +++++++++++   + + l+ e l+  + l+ +++nWr+
    EEA22480.1 457 VNDFEGYEIQNAEIKASA------LRHTPLCLAEYELSVIAADVLKEFYTLKAVRSSSTLS-ELLNRAQPLRARIENWRQ 529
                   444466666666666665......46788889999999999***********999999999.999*************95 PP

>> Duffy_binding  Duffy binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.3   4.7e-06     0.042     133     161 ..     421     449 ..     407     478 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 4.7e-06
  Duffy_binding 133 lredwWeanreeiWkamtcaltykektak 161
                     r  wW ++ +++W+am+ a + + ++++
     EEA22480.1 421 RRRLWWYTYMQHVWQAMVIARPLHLNDDS 449
                    5788**************99988776665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (649 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       437  (0.0243739); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.73u 0.36s 00:00:01.08 Elapsed: 00:00:00.56
# Mc/sec: 3477.56
//
Query:       EEA22481.1  [L=541]
Description: benzoate 4-monooxygenase cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-64  218.1   0.0    2.6e-64  217.7   0.0    1.1  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  217.7   0.0   1.4e-68   2.6e-64       9     454 ..     104     524 ..      97     533 .. 0.86

  Alignments for each domain:
  == domain 1  score: 217.7 bits;  conditional E-value: 1.4e-68
                 CCHCHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGH..HHHHHHHHHHHHH CS
        p450   9 lvgnllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfang..ekwkklRrfltpt 105
                 ++ n+l  + k + +ev++kl+++yg+ +r+ + +     +++p a   +++ +++ ++g      ++      + +  +++++  +++ + R+   ++
  EEA22481.1 104 WYANILSAK-KLHNFEVVDKLHRQYGDYVRIGPRE---LSITDPRALPFIYGPTSQTTKG-----PFYD---GAQPYISVHSTRnkKDHARRRKGWDRA 190
                 556777776.5788999**********99987665...4578999******999644444.....4555...344444444444226666777778888 PP

                 HTSHSTT.THHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCCCHHHTCCSC CS
        p450 106 ltsfgkl.sleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledeklselvkaveelssllskssvqllllfpllkylpt 203
                 + s+ +l  +ee+v ++a++l+  l +++g++  +d++++++++ +dvig+++Fg++fd+l + k+  ++k  +e ++ l  + + ++ ++pl+k +p+
  EEA22481.1 191 FSSK-SLrDYEERVSKYAAQLLSVLADNVGQP--IDMSRWFNYYSFDVIGDLTFGKSFDMLITGKDAYMLKTLHEQMQSLGPFLHSIW-VIPLFKLIPG 285
                 8888.8889***********************..********************************9999999999999966665555.5566888887 PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHH CS
        p450 204 kllrklkeavkklkdlldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklreE 302
                      l+     +++ ++k +e+r +++ ++   + +f+++  +   + k+ ++ ++ +   +v + ++aG+d t+stl+  +yeLa  Pe +  l+ E
  EEA22481.1 286 LNSSYLE-----YFEWVKKQVENRFKNVPED---PDMFMQLETDFN-KGKQ-TTKDKMHFYGEVNTGIVAGSDSTASTLTNLFYELAIAPEFTLLLQSE 374
                 6666666.....5688888888888888888...999999999995.3333.478889999************************************** PP

                 HHHHCCTTTT-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS.CEEETTEEE-TT-EEEEEHHHHHT-TTTSSSTTS--GGGGB-TTSCTESSCT CS
        p450 303 idevlgdkreptyddlqklpyldavikEtLRlhpvvplllpRevtk.dvvirgylipkGtevivnlyalhrdpevfpnPeeFdpeRFldekgnskrksf 400
                 id+v    +epty+dl+++++l+a+i Et+Rlhp++p++++R +++  v i++  ip ++ v+++ly+l rd+  f +P+eF p+R+ d+     ++s 
  EEA22481.1 375 IDTV----KEPTYQDLSRMKLLNAAIDETMRLHPAIPSGMQRLTPQkGVMIDDIYIPGDCLVQIPLYSLFRDERSFVRPNEFIPQRWIDRLDLV-KNSS 468
                 *998....689*********************************99899*****************************************9855.**** PP

                 T--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGEEESSC..SSEE CS
        p450 401 aflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdpppileks..glll 454
                 a+ PFG Gp +C G++lA me++ + + lL+++++++ ++++ +  +e++  +++l
  EEA22481.1 469 AYAPFGLGPFACAGKQLALMEIRRITVELLSRYDISFAKDQTREAFYEGQqdAFTL 524
                 **************************************999999998887665555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (541 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       349  (0.0194657); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.72u 0.34s 00:00:01.06 Elapsed: 00:00:00.56
# Mc/sec: 2933.95
//
Query:       EEA22482.1  [L=570]
Description: hypothetical protein PMAA_091110 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-32  112.0   2.3    3.2e-32  110.9   2.3    1.6  1  DUF3176       Protein of unknown function (DUF3176)
  ------ inclusion threshold ------
        0.1   12.5   0.0       0.25   11.3   0.0    1.6  1  Orthoreo_P10  Orthoreovirus membrane fusion protein p10
       0.15   12.8   3.2        1.2   10.0   0.1    2.8  2  HKR_ArcB_TM   Histidine kinase receptor ArcB trans-membrane d


Domain annotation for each model (and alignments):
>> DUF3176  Protein of unknown function (DUF3176)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.9   2.3   5.3e-36   3.2e-32       1     106 [.     111     219 ..     111     220 .. 0.97

  Alignments for each domain:
  == domain 1  score: 110.9 bits;  conditional E-value: 5.3e-36
     DUF3176   1 ivillasdgkplskWpskitlnvliailstvakaalllavaegisqlkWrwfsekprplsdleafdeasrGpwgalkllwrlkl...aslgalltilal 96 
                 +v+l ++d++++++Wp +itln l+a+l+++ + +++++v +g+sq+kW+wf++k+rpl+d+e+fd+asrG+wg+++ll+++k+   ++l+a+l++++ 
  EEA22482.1 111 VVVLHQFDQHKIPSWPLGITLNNLLAFLTAIGQSTFVFPVVQGLSQMKWTWFMGKNRPLEDFERFDNASRGAWGSIMLLFSTKGrlsILLAAILIVTSA 209
                 699*************77***********************************99*******************************9999********* PP

     DUF3176  97 avgpflQqav 106
                 ++++++Q ++
  EEA22482.1 210 VTSTITQAVL 219
                 *******986 PP

>> Orthoreo_P10  Orthoreovirus membrane fusion protein p10
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   4.2e-05      0.25      34      93 ..     471     531 ..     451     536 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 4.2e-05
  Orthoreo_P10  34 atssliaywpylaagggliviilllallycckakv.kadavrsvfrrelvalssgkvnaap 93 
                   + s ++  wpyl   g  +v+ +++ + +    kv k d  ++     l+a+s     +  
    EEA22482.1 471 SESYVVVRWPYLIFLGTQVVLTIIFLIWIVLDSKVrKVDILKDSVLAGLLAISAEDKASLE 531
                   56889999*****999999999998888888888835688899999999999887766665 PP

>> HKR_ArcB_TM  Histidine kinase receptor ArcB trans-membrane domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.1    0.0002       1.2       7      38 ..     194     225 ..     192     231 .. 0.92
   2 ?    2.2   0.4     0.053   3.1e+02      21      50 ..     490     520 ..     477     523 .. 0.72

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.0002
  HKR_ArcB_TM   7 vrfSlllvlllivlalliqillslllsgevei 38 
                   r+S+ll+++liv++ +++++++ +ls++v++
   EEA22482.1 194 GRLSILLAAILIVTSAVTSTITQAVLSQDVRY 225
                  599************************99975 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.053
  HKR_ArcB_TM  21 alliqillslllsgeveiedllr.silfgll 50 
                   l+i +l+ ++l+++v+ +d+l+ s+l gll
   EEA22482.1 490 VLTIIFLIWIVLDSKVRKVDILKdSVLAGLL 520
                  45566788899*********99636666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (570 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       591  (0.0329634); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.74u 0.33s 00:00:01.07 Elapsed: 00:00:00.55
# Mc/sec: 3123.40
//
Query:       EEA22483.1  [L=147]
Description: hypothetical protein PMAA_091120 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (147 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       344  (0.0191868); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.58u 0.30s 00:00:00.87 Elapsed: 00:00:00.53
# Mc/sec: 835.43
//
Query:       EEA22484.1  [L=349]
Description: electron transfer flavoprotein alpha subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.4e-43  147.3   2.9    8.2e-43  146.4   2.9    1.4  1  ETF            Electron transfer flavoprotein domain
    1.4e-33  114.7   1.5    1.7e-33  114.5   0.3    1.8  2  ETF_alpha      Electron transfer flavoprotein FAD-binding dom
  ------ inclusion threshold ------
      0.016   14.6   0.0      0.027   13.8   0.0    1.3  1  Orn_Arg_deC_N  Pyridoxal-dependent decarboxylase, pyridoxal b


Domain annotation for each model (and alignments):
>> ETF  Electron transfer flavoprotein domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  146.4   2.9   1.4e-46   8.2e-43       1     175 [.      37     202 ..      37     209 .. 0.94

  Alignments for each domain:
  == domain 1  score: 146.4 bits;  conditional E-value: 1.4e-46
                 EEEEE-EC.CCCE-HHHHHHHHHHHHHHHHHT--EEEEEEES....S-CHHHHHHCT-SEEEEEE-GGGSS--CCHHHHHHHHHHHHC--SEEEEESSC CS
         ETF   1 vlvlaehgvdgklnpvdlealeaArrlkekaggevtavvvGppeaeealrealaamGadkvilvddpalagydaeatakalaalikkedpdlvlagata 99 
                 +l + e++ +gkl+ ++l+a++aA +l    gg+vt++v+G+  + +a  ea++ +G++kv+ v+++a++  ++e++a++l++ ik+ ++++v+ag++a
  EEA22484.1  37 TLAVLEQR-GGKLSSASLSAIAAAQKL----GGSVTGFVAGDGVKSSAAVEAAKIKGVEKVVAVENAAYEKGLPENYAPLLVDNIKSGGYTHVIAGHSA 130
                 578999*8.******************....9**********9999999999999******************************************** PP

                 CHHHHHHHHHHHCT-EEEEEESEEEEETCCEEEEEECCCCTEEEEEE-TSSSEEEEE-TTSS----S-TT---EEE CS
         ETF 100 igkqvaprlAalLgvplitdvteleveggkltvtRpieggnglaevveadlpavltvrpgafepaaimaakkkeve 175
                 +gk ++pr+AalL+v++i+d+t++e+e +  t++Rpi++gn++ +v++ d+++v+tvr +af+  ++ + +++e++
  EEA22484.1 131 FGKGLLPRVAALLDVQQISDITAIESE-D--TFVRPIYAGNAILTVQSEDPIKVITVRGTAFQGTET-EGGSAEIV 202
                 **************************9.9..*******************************99554.44666664 PP

>> ETF_alpha  Electron transfer flavoprotein FAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0       1.8   1.1e+04      13      24 ..      72      83 ..      70      99 .. 0.60
   2 !  114.5   0.3   2.8e-37   1.7e-33       2      84 .]     227     310 ..     226     310 .. 0.97

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 1.8
                -GGGSSGGGHHH CS
   ETF_alpha 13 GrGlkskenlel 24
                G G+ks++++e 
  EEA22484.1 72 GDGVKSSAAVEA 83
                777777555543 PP

  == domain 2  score: 114.5 bits;  conditional E-value: 2.8e-37
                 -TTT-S-EEEE-GGGSSGGGHH.HHHHHHHHHT-EEEE-HHHHTTTSS-CCCB-SSSS-----S-EEEES----HHHHGGGTT- CS
   ETF_alpha   2 dLeeakvvvsgGrGlkskenle.lleelaealgaavgasRavvdagwipeerqvGqtGktvaPklyiavGisGaiqhlaGmkes 84 
                 dL++a++vvsgGrGlkske+++ ++  la+algaa+gasRa+vd+g+++++ qvGqtGk+vaP+ly+a+GisGaiqhlaGmk+s
  EEA22484.1 227 DLATASRVVSGGRGLKSKEEFDrVMVPLADALGAAIGASRAAVDSGYADNSLQVGQTGKNVAPQLYLAAGISGAIQHLAGMKDS 310
                 899******************768999*******************************************************97 PP

>> Orn_Arg_deC_N  Pyridoxal-dependent decarboxylase, pyridoxal binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0   4.6e-06     0.027       9      91 ..      11      97 ..       8     108 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 4.6e-06
                   HHHHHHCTCCEEEEEGGG---HHHHH...HHHHTTEEEEESSHHHHHHHHHCTTTGGGEEEEESS--HHHHHHHHHCTHTEEE.ESS CS
  Orn_Arg_deC_N  9 krwkkalprikvfYavKansdlavle...llaelGlgldcaSkaElelvlaagvsperiifanpckqreelryalekgvkvvt.vdn 91
                   ++++++l + ++++ v+    +++l+   +l++ G +l +aS   +++++++g+s    +  +++k+ + +++a+ kgv++v+ v+n
     EEA22484.1 11 RAVRSQLHPSRPIFDVRLSALTRLLStlaVLEQRGGKLSSASLSAIAAAQKLGGSVTGFVAGDGVKSSAAVEAAKIKGVEKVVaVEN 97
                   5677788888888888888877776511166799*********************************************96541565 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (349 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       339  (0.0189079); expected 358.6 (0.02)
Passed bias filter:                      254  (0.014167); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.48
# Mc/sec: 2195.32
//
Query:       EEA22485.1  [L=388]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.9e-63  212.9   4.5    6.2e-63  212.2   4.5    1.3  1  Ribosomal_L1  Ribosomal protein L1p/L10e family


Domain annotation for each model (and alignments):
>> Ribosomal_L1  Ribosomal protein L1p/L10e family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  212.2   4.5   3.4e-67   6.2e-63       2     204 .]      33     297 ..      32     297 .. 0.91

  Alignments for each domain:
  == domain 1  score: 212.2 bits;  conditional E-value: 3.4e-67
                   HHHS-SSS--E..........................EEEEEEESSS-TTSGGG-.-EEEEE-STSTSSC..S-EEEEE-HHHHH...HHHHTT... CS
  Ribosomal_L1   2 lkhakkkfdes..........................veialnlttkkpkkadqr.kpgkipLphplgke..vkiclitkdpqaeyakeakeag... 66 
                   l h+k++++++                          + ++l +ttkk+  +++r kp ki++p++l+k+  ++iclit+dpq++ ++ ++++    
    EEA22485.1  33 LRHIKSEQKDQeeastkktligddddesdaegspstsELVWLVITTKKHVVDKNRlKPSKISIPNSLNKSssLNICLITADPQRSVKDIIADPAfps 129
                   666655433333456777788888888888888888899******************************99999************88888888888 PP

                   ......-SEEETCHHHHHHT-HHHHHHTCCH-SEEEEEGGGHHHHHHHCHHHHGGGT-S-ECC...C.....T..BTS-.................. CS
  Ribosomal_L1  67 ....riakviglkklkkkyksfeakrkllkefdlfladdrimpllpklLGkvfgkrkkmPipv.ltk.....gt.vked.................. 134
                       ri+kvigl+kl+++yksfe++r+ll+e+d+fladdri+ +l ++LGkvf++++k+Pip+ +++     g+ vk+d                  
    EEA22485.1 130 elssRITKVIGLTKLRDRYKSFESRRQLLSEHDVFLADDRIIMRLVETLGKVFYQSSKRPIPIrIEQiekvdGKrVKKDpkskpskderkasfaplq 226
                   999************************************************************644477788666888899999************* PP

                   .HHHHHHHHCTTEEEEE-TTTSEEEEEEEETTSSHHHHHHHHHHHHHHHHHT.STTTSGSEEEEEEEETTS- CS
  Ribosomal_L1 135 .vkkevekalkstvvvrldkgtclsvkvGklsftaeelaeNieavvkalvek.vpkkwkniksiylkttmsp 204
                    v+ke+ekal+++ v++ +++t++sv+vG+++ft+e+laeN++avv+ l+ek + k+w+n+k+i++k+t+++
    EEA22485.1 227 vVAKEIEKALNCAPVYL-APSTTTSVRVGSTKFTPEQLAENVKAVVNGLTEKfITKGWRNVKAIHVKGTSTM 297
                   *************9999.***************************************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (388 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1423  (0.0793686); expected 358.6 (0.02)
Passed bias filter:                      462  (0.0257683); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.26s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 2573.86
//
Query:       EEA22486.1  [L=425]
Description: SUN domain protein (Uth1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.8e-85  283.9  10.5    1.4e-84  283.4  10.5    1.2  1  SUN       Beta-glucosidase (SUN family)
  ------ inclusion threshold ------
      0.083   11.7   0.0       0.12   11.1   0.0    1.1  1  RHSP      Retrotransposon hot spot protein


Domain annotation for each model (and alignments):
>> SUN  Beta-glucosidase (SUN family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  283.4  10.5   1.6e-88   1.4e-84       1     245 []     155     412 ..     155     412 .. 0.93

  Alignments for each domain:
  == domain 1  score: 283.4 bits;  conditional E-value: 1.6e-88
         SUN   1 dgkikCsefpsdeglvavdalglgGwagiqd..............vkgesqeCkegsyCsyaCppGylktqwpsaqgatgssvGGLyCnkdGklektnk 85 
                 dg+++C++fps++g+v++d +glgGw+giq               ++ ++++C+eg++Csy+Cp+Gylk+qwp +qgatg+svGG+ C + Gkl +tn+
  EEA22486.1 155 DGELSCDTFPSKYGAVPLDFHGLGGWSGIQYptfnslqtlvenivTAVTGESCTEGAFCSYQCPEGYLKSQWPVTQGATGQSVGGIKC-SGGKLVRTNP 252
                 6899***************************************984444667************************************.69******** PP

         SUN  86 dskklCekgagkvkvknklsksvavCrTdyPGtEamlipteveagssaelavpdedtyykwkgkktsaqYYvNkaGvsvedaCvWgseskp.vGNwapl 183
                 ++++lC++g+ +++vkn+ls++v++CrTdyPGtE++++p +v++g++ +la+pd dtyy+w+gk+tsaqYY+N+aG +v+ aC+Wgs+s+p +GNwap+
  EEA22486.1 253 EYETLCIAGVPALSVKNTLSETVCICRTDYPGTESETLPSCVSPGQTIQLANPDGDTYYQWQGKSTSAQYYINPAGADVSSACTWGSASEPtLGNWAPM 351
                 *****************************************************************************************9989****** PP

         SUN 184 vlGagkdedgktylsifqN.ptskeklnfnvkieaeegdsvsgkCkyesgklskgggadgCtv 245
                 +lG g++  g ty sif+N pt+++ l+fnv+ e+++++  s + + ++ k+++g++++gCtv
  EEA22486.1 352 NLGLGYKG-GLTYASIFPNtPTTSSLLEFNVRYEGASSQ-CSWDASARTYKSTGGDSSSGCTV 412
                 *******9.************************555444.33444444667777788****98 PP

>> RHSP  Retrotransposon hot spot protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   1.4e-05      0.12     229     274 ..     299     343 ..     282     352 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 1.4e-05
        RHSP 229 vivlasPdkksykeWkeekravriiinCdeekdlkaivvWkklaka 274
                 +i la Pd + y++W+ +  + +++in     d+ +++ W+  +++
  EEA22486.1 299 TIQLANPDGDTYYQWQGKSTSAQYYINP-AGADVSSACTWGSASEP 343
                 5889***********************5.678********998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (425 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1160  (0.0646996); expected 358.6 (0.02)
Passed bias filter:                      568  (0.0316805); expected 358.6 (0.02)
Passed Vit filter:                        93  (0.00518713); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.66u 0.29s 00:00:00.95 Elapsed: 00:00:00.45
# Mc/sec: 2860.97
//
Query:       EEA22487.1  [L=524]
Description: transcription factor Tos4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
       0.11   12.5   0.0       0.23   11.5   0.0    1.6  1  Dicty_CAD  Cell-cell adhesion domain


Domain annotation for each model (and alignments):
>> Dicty_CAD  Cell-cell adhesion domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   1.3e-05      0.23       4      75 ..     103     182 ..     100     188 .. 0.75

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 1.3e-05
   Dicty_CAD   4 edGestisGkaitlPaPrifPppyfirfl...eYkteGklwdneefei.....ksgkvefdGeeydipesrggsakrddd 75 
                 e Ges + G++      ++  + ++ r      Yk  G+ +d ++ ei     +  k+ ++G+ yd+++ ++ ++ ++d 
  EEA22487.1 103 ESGESLLMGRSSASCHHQLSANRLISRVHvkaTYKPAGNPFDRDRVEImctgwNGVKLHCQGKTYDLAKGKTFTSDIKDA 182
                 567777777776666667766666666644458**************954444567*************99988877765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (524 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1056  (0.058899); expected 358.6 (0.02)
Passed bias filter:                      588  (0.032796); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.30s 00:00:00.88 Elapsed: 00:00:00.44
# Mc/sec: 3607.87
//
Query:       EEA22488.1  [L=1129]
Description: nonsense-mediated mRNA decay factor (Upf2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.2e-59  200.1   0.4      5e-35  121.1   0.1    3.2  3  MIF4G     MIF4G domain
    3.4e-40  137.9  11.0    3.4e-40  137.9  11.0    2.8  4  Upf2      Up-frameshift suppressor 2


Domain annotation for each model (and alignments):
>> MIF4G  MIF4G domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0     0.077   6.9e+02      48      76 ..      67      96 ..      17     158 .. 0.52
   2 !   75.7   0.1   4.3e-25   3.8e-21       4     207 ..     463     648 ..     461     680 .. 0.86
   3 !  121.1   0.1   5.6e-39     5e-35      10     211 ..     677     875 ..     666     876 .. 0.95

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.077
                HCGGGHHHHHHHHHHHHHHSH.HHHHHHHH CS
       MIF4G 48 eepsfsplyarlcgklnsrfq.qnFrikll 76
                ++p  + + ++++++l++rf   +F++ ++
  EEA22488.1 67 KSPGEVAAGVEIVSALHQRFGpHEFTKQIG 96
                334777777888888888777666665544 PP

  == domain 2  score: 75.7 bits;  conditional E-value: 4.3e-25
                 HHHHHHCHTTTTHHHHHHHH.HHHHHCSCHHHHHHHHHHHHHHHHHCGGGHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHC-S-HHHHHHHHHHH CS
       MIF4G   4 vkgilnklskenfevlikql.lklamdddknelkevielifekaveepsfsplyarlcgklnsrfqqnFrikllnklqeefekryeleneleenedgnr 101
                 v  +l kl + ++++ ++ql l+++  + k++++ +i+ +++++ ++ + +ply+rl+++l ++++ ++ ++l+++l eef++      +  +++++  
  EEA22488.1 463 VDALLVKLPDLQTKDQVDQLaLDFCFLNSKASRNRLIKALQDIPKGRTDLLPLYSRLVATLGQHMP-DIPQGLIAYLDEEFRS-----LQRRKQKEFLG 555
                 5667778888888888888745777777889***********************************.****************.....68888899999 PP

                 HHHHHHHHHHHHHHHTTSSEHHHHHHHHHHHHHGGCCCCSCCHSCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHCSSSSHHHHH CS
       MIF4G 102 rrrlglvrflgelfklkmltskilldclkellssltketaddppqdleeieilltllttigktlennekakkeldqffkriqkiledatrqelssrirf 200
                 + r  ++r+l el k+++++++++++clk +l+++ +           +iei+ +ll+++g++l +n+++++++  f++ + +++      +l  + r+
  EEA22488.1 556 QVRMINIRYLAELTKFGVVPEHVIFHCLKVCLDDFSR----------TNIEIMGNLLENCGRYLLRNPETSPRMSSFLETVGRKKAA---THLGQQERM 641
                 99999********************************..........99********************************999997...444444444 PP

                 HHHHHHH CS
       MIF4G 201 mlkdlie 207
                  +++ ++
  EEA22488.1 642 IIENAMY 648
                 4444444 PP

  == domain 3  score: 121.1 bits;  conditional E-value: 5.6e-39
                 CHTTTTHHHHHHHHHHHHHCSCHHHHHHHHHHHHHHHHHCG.GGHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHC-S-HHHHHHHHHHHHHHHHH CS
       MIF4G  10 klskenfevlikqllklamdddknelkevielifekaveep.sfsplyarlcgklnsrfqqnFrikllnklqeefekryeleneleenedgnrrrrlgl 107
                  + k n+++++k+++kl++++  +e   ++e +f+ +++    +++l+a l+++l+ ++q +F+i+++++++e ++       +le ne +++++r + 
  EEA22488.1 677 DMNKRNYTKILKSIRKLHWEE--SEVVDILERVFSRPHKVKyGNIHLLAILASALYRYHQ-EFVISVVDNVLESITL------GLELNEFKFNQKRVAE 766
                 46699***************9..99************99656******************.****************......**************** PP

                 HHHHHHHHHTTSSEHHHHHHHHHHHHHGGCCCCSC........CHSCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHCSSSSHHH CS
       MIF4G 108 vrflgelfklkmltskilldclkellssltketad........dppqdleeieilltllttigktlennekakkeldqffkriqkiledatrqelssri 198
                 v++lgel+++km++s +++d l+++  +++++  +        d p+d ++i++++t+l+t+g  ++ + +akk+ld f++++q ++  +  + l++++
  EEA22488.1 767 VKYLGELYNYKMIDSPVIFDALYRIVAFGHENGTPspskinilDMPDDFFRIRLVCTILDTCGVCFD-RGSAKKKLDFFLTYFQYYIFTK--DPLPMDV 862
                 *******************************98889*******************************.********************98..******* PP

                 HHHHHHHHHHHHT CS
       MIF4G 199 rfmlkdlielkkn 211
                 +f+++d + l+++
  EEA22488.1 863 DFLVQDTYSLVRP 875
                 *******999875 PP

>> Upf2  Up-frameshift suppressor 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.6      0.64   5.7e+03     117     131 ..     114     128 ..     107     132 .. 0.72
   2 ?   -3.1   0.2       1.3   1.2e+04      16      59 ..     269     309 ..     257     336 .. 0.55
   3 ?   -2.3   0.2      0.77   6.9e+03      46      77 ..     401     434 ..     387     452 .. 0.49
   4 !  137.9  11.0   3.8e-44   3.4e-40       2     135 ..     964    1087 ..     962    1088 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.64
        Upf2 117 reqeeaekeEkeriK 131
                 ++q+ +e+eEker+ 
  EEA22488.1 114 LSQDVREREEKERLS 128
                 567777888888775 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 1.3
        Upf2  16 eeeeeFerelakmmaeslesrknerk.kapqldvplPmnvkkkkk 59 
                  + e ++  ++ +++  le+ k + +      + +l ++++++ +
  EEA22488.1 269 LASEKLQLRFKNILTRYLEDVKAHVVrD----QKALTAQSRRNAE 309
                 6777788888888888887777777722....3444444433333 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 0.77
        Upf2  46 ldvplPmnvk...kkkkkaeesesssekaaeeaee 77 
                 l+ ++P+ +    kkkk+ + +e  ++++++e+++
  EEA22488.1 401 LKGKVPAVLLedgKKKKG-DIDEHAKGQDTAEKAD 434
                 466777555554322222.2222222222222222 PP

  == domain 4  score: 137.9 bits;  conditional E-value: 3.8e-44
        Upf2    2 eeeevvvrrk..evdpeeeeeFerelakmmaeslesrknerkkapql.dvplPmnvkkkkkkaeesesssekaaeeaeeepeaekskkvaFtLLtkk 95  
                  e+e++ v r+  e+dpe+e++F+r+++kmmaes+e r++erk+   l d+plPm+ ++++++          a++e++ e+++++ +++aF+L+tkk
  EEA22488.1  964 EDEKIFVARQeeERDPEAEADFDRAFEKMMAESMEGRRFERKA---LfDIPLPMRPSRREQT----------ASDETSVERPQQPANTMAFSLMTKK 1047
                  6677666666699999**************************7...77*****999533333..........223333333445569********** PP

        Upf2   96 gnKqqtktlevPsdsslaqstreqeeaekeEkeriKrlvL 135 
                  gn+qqt+t+e+Psdss+a+++++q++a++eE++riK+lvL
  EEA22488.1 1048 GNRQQTRTIELPSDSSFAIAMKTQQQADREEQQRIKNLVL 1087
                  ***************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1129 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       715  (0.0398795); expected 358.6 (0.02)
Passed bias filter:                      406  (0.0226449); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.81u 0.31s 00:00:01.12 Elapsed: 00:00:00.49
# Mc/sec: 6920.44
//
Query:       EEA22489.1  [L=311]
Description: mitochondrial intermembrane space protein Mia40 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-06   28.6   4.5    1.9e-06   27.8   4.5    1.4  1  CHCH          CHCH domain
  ------ inclusion threshold ------
      0.064   13.6   0.1       0.22   11.9   0.1    1.9  1  Cytotoxic     Cytotoxic
      0.085   13.3   2.2       0.19   12.2   2.2    1.6  1  GCK           GCK domain
        1.3    8.5   4.3        1.8    8.0   4.3    1.1  1  DUF334        Domain of unknown function (DUF334)


Domain annotation for each model (and alignments):
>> CHCH  CHCH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   4.5   4.3e-10   1.9e-06       1      34 [.     173     208 ..     173     208 .. 0.98

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 4.3e-10
                 THHHHHHHHHHHHHCTSS..TTTTHHHHHHHHHHHC CS
        CHCH   1 CgeefkeylkClkdnsde..fskCrkefeafkeCvk 34 
                 Cgeef+e+++C+ ++ +e  + +C + f+ +++C++
  EEA22489.1 173 CGEEFREAFSCFVYSHEEpkGMDCIEKFKGMQDCFR 208
                 *****************999**************85 PP

>> Cytotoxic  Cytotoxic
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.1     5e-05      0.22      47      70 ..     134     157 ..     130     160 .. 0.93

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 5e-05
   Cytotoxic  47 qhGelekYnkkgkhlGefdpktGe 70 
                 q+G le  +++ kh+G+f+p+tGe
  EEA22489.1 134 QEGGLEGLEEEAKHEGAFNPETGE 157
                 789********************8 PP

>> GCK  GCK domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   2.2   4.2e-05      0.19       9      65 ..     168     222 ..     160     230 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 4.2e-05
         GCK   9 mkgGgCkesfiawekcveeaeknkedlvekcaevtatlkkCmeahsdYYePiLaaek 65 
                 m  G+C e+f++   c+      +e     c e ++ ++ C   h++ Y   L++ +
  EEA22489.1 168 MAYGPCGEEFREAFSCFVYSH--EEPKGMDCIEKFKGMQDCFRLHPEVYGSELQEDE 222
                 889*********999986555..4677889*******************99987544 PP

>> DUF334  Domain of unknown function (DUF334)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   4.3   0.00041       1.8      62     117 ..     227     281 ..     221     302 .. 0.85

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00041
      DUF334  62 ikeqqdlrekelkeikselkkatkdfrdkskkvrndfvdllqkklkrvdaeelkii 117
                 + eq   r++e ++ik++ k+  +  ++   k+ +  v  l++  k+v++eel+  
  EEA22489.1 227 LTEQIAQRDREEQAIKAQ-KEQQQAGQQEEIKIADPAVSSLNEVEKHVETEELRRA 281
                 6788899*********87.78888899999**********************9864 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (311 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1952  (0.108874); expected 358.6 (0.02)
Passed bias filter:                      677  (0.0377601); expected 358.6 (0.02)
Passed Vit filter:                        71  (0.00396006); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.47
# Mc/sec: 1995.49
//
Query:       EEA22490.1  [L=464]
Description: septin AspB [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   1.7e-121  404.8   0.1   1.7e-121  404.8   0.1    1.5  2  Septin        Septin
    6.5e-09   35.9   0.6    1.4e-08   34.9   0.0    1.9  2  MMR_HSR1      50S ribosome-binding GTPase
     0.0001   21.9   2.0     0.0069   15.9   0.0    3.0  2  GTP_EFTU      Elongation factor Tu GTP binding domain
    0.00067   20.2   3.1      0.013   16.0   0.0    2.7  2  ABC_tran      ABC transporter
     0.0014   18.5   0.8     0.0014   18.5   0.8    3.3  2  RsgA_GTPase   RsgA GTPase
     0.0017   18.6   0.0     0.0037   17.5   0.0    1.6  1  Roc           Ras of Complex, Roc, domain of DAPkinase
     0.0032   17.9   0.1      0.011   16.2   0.0    1.9  2  AAA_16        AAA ATPase domain
     0.0041   17.4   0.6      0.019   15.3   0.0    2.4  2  AAA_22        AAA domain
     0.0048   16.2   3.1     0.0058   16.0   0.0    2.3  2  AIG1          AIG1 family
     0.0092   15.7   0.0      0.017   14.8   0.0    1.4  1  AAA_29        P-loop containing region of AAA domain
  ------ inclusion threshold ------
      0.025   14.2   0.0      0.094   12.3   0.0    2.0  1  Ras           Ras family
      0.032   13.8   4.7      0.053   13.1   4.7    1.4  1  Exonuc_VII_L  Exonuclease VII, large subunit
      0.036   14.1   6.7       0.43   10.6   0.0    3.5  2  Dynamin_N     Dynamin family
      0.042   13.6   0.0       0.11   12.2   0.0    1.8  1  AAA_24        AAA domain
      0.071   12.6   0.0       0.14   11.6   0.0    1.4  1  AAA_7         P-loop containing dynein motor region
      0.078   12.0   0.2      0.078   12.0   0.2    2.2  3  IIGP          Interferon-inducible GTPase (IIGP)
       0.14   12.5   0.5       0.84   10.0   0.0    2.3  2  RNA_helicase  RNA helicase
       0.52   10.0   4.6        2.9    7.6   0.0    3.0  3  ATP_bind_1    Conserved hypothetical ATP binding protein
        2.6    7.0  10.3        3.9    6.5  10.3    1.2  1  Atg14         Vacuolar sorting 38 and autophagy-related subun
        5.6    4.8   5.9        8.3    4.2   5.9    1.1  1  Prominin      Prominin
        5.8    6.6   7.0        1.7    8.3   3.6    1.8  2  DUF2937       Protein of unknown function (DUF2937)


Domain annotation for each model (and alignments):
>> Septin  Septin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  404.8   0.1    2e-124  1.7e-121       1     279 [.      88     367 ..      88     369 .. 0.97
   2 ?   -3.5   1.0       5.7   4.9e+03      38      60 ..     422     444 ..     389     447 .. 0.46

  Alignments for each domain:
  == domain 1  score: 404.8 bits;  conditional E-value: 2e-124
                 XEEEEEEEEEEBTTSSCCCCCCTTSSSS------------.------S-EEEEEEEEETTCEEEEEEEE---BSSSSSHHCCCHHHHHHHHHHHHHHHH CS
      Septin   1 kgieftlmvvGesglGkttlintlfetdlieeekleease.kkkktveikkkkvvieedgvklnltviDtpgfGdavdnskswepiveyideqfeeylr 98 
                 kg++f++mvvGesglGk+tlintlf+t+l++ ++ + +s+  + ktv+i+  ++ iee+gv+l+ltv+DtpgfGd+v+n++sw+pive+i+++f++yl+
  EEA22490.1  88 KGFNFNVMVVGESGLGKSTLINTLFNTSLYPPKERKGPSHdIIPKTVSIQGISADIEENGVRLRLTVVDTPGFGDFVNNDDSWRPIVENIEQRFDAYLE 186
                 79******************************999999986789******************************************************* PP

                 HCTSS--SS-----EEEEEEEE-TTSSSS-HHHHHHHHHHTTTS-EEEEESSGGGS-HHHHHHHHHHHHHHHHHTT--------SSSS-SCCHHHHHHH CS
      Septin  99 eesklkRkkivDkRvHaclyfisPtghglkpldvelmkklsekvnliPviaKaDtltkeElkefKkkireeleeeeikiyklpdeeededeeakelsek 197
                 +e+k++R +ivD+RvHac+yfi+Ptgh lkpld+e+m++l++kvnliPviaKaDtlt+eE+  fK++i ++++ ++i+i++  + +e +dee+  ++++
  EEA22490.1 187 AENKVNRMNIVDNRVHACVYFIQPTGHSLKPLDIEVMRRLHTKVNLIPVIAKADTLTDEEIALFKQRILADIQYHSIQIFE-GPRYELDDEETIAENQE 284
                 *********************************************************************************.66667777999****** PP

                 HHHC-SEEB-SSSSEEEE.SSSEEEEEEETTEEEETT-TTT-SCCHHHHHHHHHCHHHHHHHHHHTHHHHHHHHHH-XXXXXX CS
      Septin 198 lkeslPfaivgsneliek.kgkkvrgRkypWGvvevenekhsdFlkLrklllkthledLkevteellYetyRseklsklkeka 279
                 + +++Pfa+vg+n+++++ +g+kvrgR+ypWGv+ev+ne+h+dF+kLr++l++th+e+Lke t+++lYe+yRs+kl+++  ++
  EEA22490.1 285 IMSKVPFAVVGANAEVTTpDGRKVRGRRYPWGVIEVDNEEHCDFVKLRQMLIRTHMEELKEHTNNVLYENYRSDKLTQMGVAQ 367
                 ****************************************************************************9987665 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 5.7
                 ---------S-EEEEEEEEETTC CS
      Septin  38 asekkkktveikkkkvvieedgv 60 
                  + + + + +++++++ +ee++ 
  EEA22490.1 422 YARHREMKDQLERQRQDLEEKKA 444
                 11223334455555555555555 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.9   0.0   1.6e-11   1.4e-08       1     101 [.      93     226 ..      93     238 .. 0.51
   2 ?   -2.8   0.2       7.5   6.4e+03      86      86 ..     408     408 ..     369     444 .. 0.50

  Alignments for each domain:
  == domain 1  score: 34.9 bits;  conditional E-value: 1.6e-11
                 EEEEEESTTSSHHHHHHHHHTS.TEEESSSTTSSSSEEEEEEEETTEE...........EEEEECGGC................SSHHHHHHHHHHHHH CS
    MMR_HSR1   1 evaivGrpNvGKStLinaltge.kaivsdkpgtTrdinegrvklkgke...........ielvDtpGl................iegaseekglgkafl 71 
                 +v++vG +  GKStLin+l+++     ++++g   di+ ++v+++g +           +++vDtpG+                i         +++f 
  EEA22490.1  93 NVMVVGESGLGKSTLINTLFNTsLYPPKERKGPSHDIIPKTVSIQGISadieengvrlrLTVVDTPGFgdfvnnddswrpivenI---------EQRFD 182
                 599*****************9534455555555555555555544322233333444449*******655545544444432221.........33333 PP

                 H..............HHCTSEEEEEEETTTTCSHHHHHHHHHHH CS
    MMR_HSR1  72 a..............leeadlillvvdaseeklkpldeeleell 101
                 a               +++++ ++ ++ + ++lkpld e+ + l
  EEA22490.1 183 AyleaenkvnrmnivDNRVHACVYFIQPTGHSLKPLDIEVMRRL 226
                 21111111111111122345555555433445677766665555 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 7.5
                 T CS
    MMR_HSR1  86 s 86 
                 +
  EEA22490.1 408 R 408
                 1 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   8.1e-06    0.0069       5      86 ..      93     166 ..      91     169 .. 0.74
   2 ?    3.5   1.1     0.052        45     120     173 ..     227     294 ..     217     448 .. 0.78

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 8.1e-06
                 EEEEEESTTSSHHHHHHHHHHHTTSSCHHHHHHHHHSTHCHSHHHHHHTSCSSCEEEEEETTCSSEEEEEEEESSSGGGHHH CS
    GTP_EFTU   5 nigiighvDhGKtTLtdrLlyktgaiskkgekaeeervlDtlkeErergiTiksaaisleketkkylinliDtPGHvdFske 86 
                 n++++g    GK+TL+ +L  ++    k  e+++     D  +    + ++i+   + +e+++ + +++++DtPG  dF+++
  EEA22490.1  93 NVMVVGESGLGKSTLINTLFNTSLYPPK--ERKGP--SHDIIP----KTVSIQGISADIEENGVRLRLTVVDTPGFGDFVNN 166
                 99*****************966655444..66652..355554....4455555555555667779*************987 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.052
                 HTTTEEEEEEESCGST.HHHHHHHHHHHHHHHHHH..............HHHHHHHHHTTTTTEEEEEE CS
    GTP_EFTU 120 kegvpiivfiNKmDrl.kaelkeiveevkqklsrk..............eeklekygekgekevpvvfg 173
                   +v++i +i K+D l ++e+   ++ +  +++ +              ee++ + +e   ++vp++ +
  EEA22490.1 227 HTKVNLIPVIAKADTLtDEEIALFKQRILADIQYHsiqifegpryelddEETIAENQEIM-SKVPFAVV 294
                 35678**********998888888888888775556667777776655522222222222.34555444 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   1.6e-05     0.013      14      34 ..      94     114 ..      89     202 .. 0.80
   2 ?    1.2   3.5      0.56   4.8e+02      46      96 ..     384     443 ..     229     457 .. 0.86

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 1.6e-05
                 EEEEESTTSSHHHHHHHHTTS CS
                 xxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  14 vaivGenGaGKStLlkllagl 34 
                 v +vGe+G GKStL+++l + 
  EEA22490.1  94 VMVVGESGLGKSTLINTLFNT 114
                 789*************99754 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.56
                 TCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.........HHHTCHHHHHHHSTTGG CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.........xxxxxxxxxxxxxxxxx RF
    ABC_tran  46 gkdlkeqeleslrkeigvlpqepqlfpeltvren.........esdeeiekalsklglke 96 
                 ++ l+eq+l ++++e++++++++   +e++++++         e+++++e+ ++ l+ k+
  EEA22490.1 384 ERALHEQKLAKMEAEMKMVFEQKVREKESKLKQSedelyarhrEMKDQLERQRQDLEEKK 443
                 556677888889999999999877777776666678888777766666666666666554 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.8   1.7e-06    0.0014     102     122 ..      94     114 ..      54     165 .. 0.70
   2 ?    3.1   0.1     0.093        79      42      80 ..     225     263 ..     186     286 .. 0.76

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 1.7e-06
                  EEEECSTTSSHHHHHHHHCTT CS
  RsgA_GTPase 102 svlvGqSGvGKStLinallpe 122
                  +++vG+SG GKStLin+l ++
   EEA22490.1  94 VMVVGESGLGKSTLINTLFNT 114
                  5679**************886 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.093
                  HHHTT-EEEEEEE-GGG--HHHHHHHHHH.HHHHTTSEEE CS
  RsgA_GTPase  42 aeekgiepvivlnKiDlleeeeeleelke.elealgyevl 80 
                    +++++++ v+ K+D l++ee +  +k+  l++++y+ +
   EEA22490.1 225 RLHTKVNLIPVIAKADTLTDEE-IALFKQrILADIQYHSI 263
                  5678999999************.54444404566666555 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   0.0   4.3e-06    0.0037       2      66 ..      94     160 ..      93     171 .. 0.77

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 4.3e-06
                 EEEESSTTSSHHHHHHCHCT-CC.C-EEETTTTEEEEEEECGGSGGCTTB..TTTTCEEEEEEEE-SG CS
         Roc   2 vvlvGdsgvGKtsllkrfvedkf.sekekstigvdfltkevtkikgvend..kkvkkvklniWDtaGq 66 
                 v++vG+sg GK++l++ + + +   +ke++  + d++ k+v +i+g++ d  ++  +++l + Dt G 
  EEA22490.1  94 VMVVGESGLGKSTLINTLFNTSLyPPKERKGPSHDIIPKTV-SIQGISADieENGVRLRLTVVDTPGF 160
                 89***************999776268888999999999998.79988755114444567788888775 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   1.3e-05     0.011      21      46 ..      88     113 ..      80     144 .. 0.85
   2 ?   -1.8   0.1       4.1   3.5e+03      93     107 ..     387     410 ..     335     452 .. 0.51

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.3e-05
      AAA_16  21 sgrpelvllsGesGvGKsslvrellr 46 
                 +g   +v+++GesG GKs+l+++l++
  EEA22490.1  88 KGFNFNVMVVGESGLGKSTLINTLFN 113
                 5555689****************997 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 4.1
      AAA_16  93 eleawrekleeala.........a 107
                 ++e+  +k e++++          
  EEA22490.1 387 LHEQKLAKMEAEMKmvfeqkvreK 410
                 333333333333334444433220 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   2.2e-05     0.019       8      29 ..      94     115 ..      93     266 .. 0.73
   2 ?   -0.8   0.1       2.1   1.8e+03      58      77 ..     333     350 ..     306     438 .. 0.61

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 2.2e-05
      AAA_22   8 lvvtGesGtGKTtllrrlleql 29 
                 ++v+GesG GK+tl+++l+++ 
  EEA22490.1  94 VMVVGESGLGKSTLINTLFNTS 115
                 589****************986 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 2.1
      AAA_22  58 rellralglelkaerlssee 77 
                 ++l r   +elk+  +++  
  EEA22490.1 333 QMLIRTHMEELKE--HTNNV 350
                 4444444444333..22222 PP

>> AIG1  AIG1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   6.8e-06    0.0058       2      68 ..      93     169 ..      92     189 .. 0.66
   2 ?   -1.9   2.6       2.1   1.8e+03     158     205 ..     350     399 ..     320     435 .. 0.63

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 6.8e-06
                 EEEEESSTTSSHHHHHHHHHTS--SS--TT...TS---SS-...EEEEE..EETT..EEEEEEE--SCCCTTCCHHC CS
        AIG1   2 tivlvGktgnGkSaTgNsilgkkaFeskls...aqsvtkkc...qkksr..twdg..kkinViDTPglfdlsvsadk 68 
                 ++++vG +g GkS+ +N++ +++ +  k +   ++ ++ k    q  s+  +++g   ++ V+DTPg  d  +++d+
  EEA22490.1  93 NVMVVGESGLGKSTLINTLFNTSLYPPKERkgpSHDIIPKTvsiQGISAdiEENGvrLRLTVVDTPGFGDFVNNDDS 169
                 799*******************998655431114455444301033333224445545789******9887665554 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 2.1
                 EEEETTHHHH..HHHHHHHHHHHHHHHHHHHHTTTT--B-HHHHHHHHCC CS
        AIG1 158 vlfnnktask..eekeeQvkellelveaivkenggkpytnelyekikeea 205
                 vl++n +++k  ++  +Q   + + v+  vk+++++ + ++   k++ e 
  EEA22490.1 350 VLYENYRSDKltQMGVAQDPSVFKEVNPAVKQEEERALHEQKLAKMEAEM 399
                 55555544431144567777777777766655555544444333333333 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0     2e-05     0.017      24      50 ..      93     120 ..      79     123 .. 0.71

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 2e-05
      AAA_29  24 atlltGpsGsGKSTllDAi.qalLvpak 50 
                 +++++G+sG GKSTl+  + ++ L+p+k
  EEA22490.1  93 NVMVVGESGLGKSTLINTLfNTSLYPPK 120
                 689*************876245566665 PP

>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   0.00011     0.094       2      61 ..      94     163 ..      93     171 .. 0.70

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00011
                 EEEEESTTSSHHHHHHH.HHHSSCSSSCTTTSSEEEEEEEEEET.........TEEEEEEEEEETTSGGG CS
         Ras   2 lvlvGdsavGKtslllr.fvkdkFkeeyesTigvdfytkeievd.........gkevkleiwDTAGqeef 61 
                 +++vG+s+ GK++l++  f ++ ++ +  +    d   k+++++         g +++l++ DT G  +f
  EEA22490.1  94 VMVVGESGLGKSTLINTlFNTSLYPPKERKGPSHDIIPKTVSIQgisadieenGVRLRLTVVDTPGFGDF 163
                 789***********9863667778777665444554444444444444444449999999****998777 PP

>> Exonuc_VII_L  Exonuclease VII, large subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   4.7   6.2e-05     0.053     175     258 ..     376     448 ..     296     463 .. 0.53

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 6.2e-05
  Exonuc_VII_L 175 asrlkspeellerkrqrldeleerleralkkqlkkkrerleelkerl.k......ekleekkerlkklkerlelleekkerleeleeklea 258
                   + ++k +ee  + ++q+l ++e++++   ++++++k+++l++ +++l        ++le+++++l++ k+rle                 +
    EEA22490.1 376 NPAVK-QEEERALHEQKLAKMEAEMKMVFEQKVREKESKLKQSEDELyArhremkDQLERQRQDLEEKKARLE-----------------S 448
                   33333.2233334455566666666666666666666666666655533233333333333333333333333.................2 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0    0.0005      0.43       1      25 [.      94     118 ..      94     125 .. 0.87
   2 ?    5.0   0.0     0.027        23     100     119 ..     149     168 ..     134     205 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.0005
                 EEEEEBTTTTHHHHHHHHHTS--S- CS
   Dynamin_N   1 iavvGsqSsGKSSvlnaLlgedilp 25 
                 ++vvG+   GKS+++n L    + p
  EEA22490.1  94 VMVVGESGLGKSTLINTLFNTSLYP 118
                 79****************9887766 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.027
                 S-SEEEEE---B-SSSGTTS CS
   Dynamin_N 100 vkgltlvDlPGldsvnkrdq 119
                 + +lt+vD+PG+ +  ++d 
  EEA22490.1 149 RLRLTVVDTPGFGDFVNNDD 168
                 5789********98444443 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00013      0.11       4      31 ..      93     120 ..      91     199 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00013
      AAA_24   4 kiliyGpsgiGKTtlakelgpkplfidt 31 
                 +++++G+sg GK+tl+++l ++ l+   
  EEA22490.1  93 NVMVVGESGLGKSTLINTLFNTSLYPPK 120
                 799***************9555555444 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   0.00017      0.14      34      55 ..      92     113 ..      84     121 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00017
       AAA_7  34 kpvllvGptGtGKtviikdllk 55 
                  +v++vG++G GK+++i++l++
  EEA22490.1  92 FNVMVVGESGLGKSTLINTLFN 113
                 68****************9655 PP

>> IIGP  Interferon-inducible GTPase (IIGP)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.2   9.1e-05     0.078      35      55 ..      91     111 ..      84     114 .. 0.90
   2 ?   -3.2   0.0       3.8   3.2e+03     201     224 ..     323     347 ..     317     373 .. 0.69
   3 ?   -1.3   0.6       1.1     9e+02     209     247 ..     379     417 ..     340     432 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 9.1e-05
                 -EEEEEEESTTSSHHHHHHHH CS
        IIGP  35 klkiavtGdsGnGkssFinaL 55 
                 + +++v+G+sG Gks+ in+L
  EEA22490.1  91 NFNVMVVGESGLGKSTLINTL 111
                 5799****************9 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 3.8
                 TTSTTHHHHHHHHHH.HS-GGGHHH CS
        IIGP 201 vsayDFPkLretLlk.dlpaikrhe 224
                  ++ DF kLr+ L++  +   k h+
  EEA22490.1 323 EEHCDFVKLRQMLIRtHMEELKEHT 347
                 5667888888888752344455544 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 1.1
                 HHHHHHHHS-GGGHHHHHHHS---SHHHHHHHHHHHHHH CS
        IIGP 209 LretLlkdlpaikrhefleslsnvtdkvieekreslkqk 247
                 +++   + l   k  ++   ++ v ++ + ek++ lkq+
  EEA22490.1 379 VKQEEERALHEQKLAKMEAEMKMVFEQKVREKESKLKQS 417
                 555555667777778888888888888888888888876 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00099      0.84       1      23 [.      94     116 ..      94     133 .. 0.83
   2 ?   -0.4   0.2       1.7   1.5e+03      17      84 ..     334     403 ..     330     418 .. 0.60

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00099
  RNA_helicase   1 iwlyGpsgeGKStlakeLakall 23 
                   ++++G+sg GKStl+++L ++ l
    EEA22490.1  94 VMVVGESGLGKSTLINTLFNTSL 116
                   6899*************987655 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 1.7
  RNA_helicase  17 eLakallkklklkkkdsvysrnpeddfwdgYt.gqevvvidDfgqvkdee.nps.dlaelirlvsstpypl 84 
                    L+++ +++lk+++ ++v + n ++d + +    q+  v+ +++  +++e +    ++ l ++    ++  
    EEA22490.1 334 MLIRTHMEELKEHT-NNVLYENYRSDKLTQMGvAQDPSVFKEVNPAVKQEeERAlHEQKLAKMEAEMKMVF 403
                   57777788886666.55555555555554444488888888887777665455555555555555554444 PP

>> ATP_bind_1  Conserved hypothetical ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0     0.082        70       1      17 [.      96     112 ..      96     117 .. 0.90
   2 ?    7.6   0.0    0.0034       2.9      85     214 ..     142     289 ..     132     302 .. 0.64
   3 ?   -2.9   0.4       5.4   4.7e+03     198     214 ..     386     402 ..     338     432 .. 0.57

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.082
  ATP_bind_1   1 vvGpaGsGKttfvgals 17 
                 vvG  G GK+t++++l 
  EEA22490.1  96 VVGESGLGKSTLINTLF 112
                 89***********9986 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0034
  ATP_bind_1  85 eleke.ed.dyllfDtPGQielfthseslakiveeLesef........alvvvyLvDsqrltd.....ptkf.isgllsalsamlrlelPhvvvlnkfD 167
                 ++e++  +  + ++DtPG   +++  +s + ive++e++f        ++  +++vD ++ +      pt   ++ l + +   l++++  + v+ k+D
  EEA22490.1 142 DIEENgVRlRLTVVDTPGFGDFVNNDDSWRPIVENIEQRFdayleaenKVNRMNIVDNRVHACvyfiqPTGHsLKPLDIEVMRRLHTKVNLIPVIAKAD 240
                 555554335899***********************9997611222221344577777766665443332222022222333334556777888888888 PP

  ATP_bind_1 168 llkek..lekeleffedvealslllekeeekykklaeaiaelleefalv 214
                  l ++  + ++   + d++++s  + +  ++  + +e+iae  e ++ v
  EEA22490.1 241 TLTDEeiALFKQRILADIQYHSIQIFEGPRYELDDEETIAENQEIMSKV 289
                 8887777777777788887777777666677777777776665555555 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 5.4
  ATP_bind_1 198 kklaeaiaelleefalv 214
                 + +++++a++  e+++v
  EEA22490.1 386 ALHEQKLAKMEAEMKMV 402
                 22233333333333332 PP

>> Atg14  Vacuolar sorting 38 and autophagy-related subunit 14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5  10.3    0.0045       3.9      43     122 ..     373     450 ..     330     462 .. 0.73

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0045
       Atg14  43 kkiekalegkeeaeqledkiknkkakleelksliadlrerlqelkdklsqlkkeieekkkklaklsdklkkRrsdleslq 122
                 k+++ a++++e  e++  + k  k+ +e +    ++ re+ ++lk++ ++l ++++e k +l++++++l +++++les +
  EEA22490.1 373 KEVNPAVKQEE--ERALHEQKLAKMEAEMKMVFEQKVREKESKLKQSEDELYARHREMKDQLERQRQDLEEKKARLESGR 450
                 44455555555..6677777777788888888888888888888888888888888888888888888888888888754 PP

>> Prominin  Prominin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   5.9    0.0097       8.3     185     289 ..     336     438 ..     330     449 .. 0.80

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.0097
    Prominin 185 lrtflkdvpqhidhvlvqnyeelekhvsddLddagkhlgldladtlesnvlpaLae..lerllenlkeakeqLeqvnklekeLrksgsqLrdglrgvkr 281
                 +rt +++  +h ++vl +ny+  +  ++++    + +++++++ +++++  +aL+e  l+++  ++k + e  ++v++ e++L++s ++L +  r++k+
  EEA22490.1 336 IRTHMEELKEHTNNVLYENYRSDK--LTQMGVAQDPSVFKEVNPAVKQEEERALHEqkLAKMEAEMKMVFE--QKVREKESKLKQSEDELYARHREMKD 430
                 68999***************9866..7777777779***********999999976224555555554444..47999999999999999999999999 PP

    Prominin 282 dlnqalsn 289
                 +l++  ++
  EEA22490.1 431 QLERQRQD 438
                 99987665 PP

>> DUF2937  Protein of unknown function (DUF2937)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.1       4.2   3.6e+03      65      85 ..      45      66 ..      40      70 .. 0.72
   2 ?    8.3   3.6     0.002       1.7      39     104 ..     389     454 ..     385     457 .. 0.94

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 4.2
     DUF2937 65 rqsedp.vvradaesiqalver 85
                 +s+dp +v++ a+ ++++v+r
  EEA22490.1 45 VSSKDPkAVAQAATDMRNVVRR 66
                5566652688888999999988 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.002
     DUF2937  39 krqlagfqatAkrffkgdlealiahyrqsedpvvradaesiqalverlerLeqelqalqqasller 104
                 +++la+++a+ k+ f+  +++  ++++qsed+  ++  e++++l ++ ++Le++ ++l+++ +le+
  EEA22490.1 389 EQKLAKMEAEMKMVFEQKVREKESKLKQSEDELYARHREMKDQLERQRQDLEEKKARLESGRPLEK 454
                 68899999999999*99*******************************************999887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (464 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2016  (0.112444); expected 358.6 (0.02)
Passed bias filter:                      705  (0.0393218); expected 358.6 (0.02)
Passed Vit filter:                       125  (0.00697194); expected 17.9 (0.001)
Passed Fwd filter:                        25  (0.00139439); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              21  [number of targets reported over threshold]
# CPU time: 0.79u 0.34s 00:00:01.13 Elapsed: 00:00:00.52
# Mc/sec: 2676.72
//
Query:       EEA22491.1  [L=289]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      5e-33  114.5   4.2    6.8e-33  114.1   4.2    1.0  1  UPF0121   Uncharacterised protein family (UPF0121)


Domain annotation for each model (and alignments):
>> UPF0121  Uncharacterised protein family (UPF0121)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.1   4.2   3.8e-37   6.8e-33      12     230 ..      16     259 ..      12     267 .. 0.85

  Alignments for each domain:
  == domain 1  score: 114.1 bits;  conditional E-value: 3.8e-37
     UPF0121  12 hlkankielalwltrlltllftvlyli.plflsssys.....aYykallanaatsalrlhqrl.pqlrlsreyle...rllledsvhyLlysliFlfsa 100
                 ++ a+++++ +++ +l++ll+++ y +  +f++  ys      Y+ a++++aat+ +++++++  + +ls + l+   +ll++++v+yL  +l++l+s+
  EEA22491.1  16 KALAQTLQFGWFVGHLTLLLSVFRYGLsYIFFN-YYSrwakiSYRLAFISAAATYGIVVYKQYiARGKLSGSPLQiavKLLSDENVQYLGMALVWLYSR 113
                 567899*******************99667777.666678888******************99766688865544223899****************** PP

     UPF0121 101 PvtlallPvflfallHaasytktlld...................vlgsnslvvarll..kvislvesqaeniLrliAlieivlmpllivllllg.kas 177
                  + lallP+ +++++H+a+yt+t l                             ++ l  ++ ++v++ + + ++l+A  e+ l++ l++ +l++ k s
  EEA22491.1 114 QIPLALLPFSVYSVFHVATYTRTYLLptlqpvpqgatgptspggsR----PAAKQSPLaeTIGKFVKQYYDSSMYLVASLELGLLFRLVLSALTFsKGS 208
                 ***********************************88888754431....22222222234589******************88888888877651679 PP

     UPF0121 178 lllpllYyqfLklRYsSrrnPytreafseLrvlletlanhpscPavirsliek 230
                  +l+++Y  f + RYs  ++   + a++ + + ++tl++h ++P+ +r+  e 
  EEA22491.1 209 WVLLVIYLAFFRARYS--QSSFVQSAVTRFTARVDTLVSHQNTPPQVRQGWEA 259
                 9***************..*****************************998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (289 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       474  (0.0264376); expected 358.6 (0.02)
Passed bias filter:                      277  (0.0154498); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.23s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1985.34
//
Query:       EEA22492.1  [L=444]
Description: mitochondrial carrier protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.9e-60  200.2   2.9    9.1e-19   67.2   1.2    3.8  3  Mito_carr  Mitochondrial carrier protein
  ------ inclusion threshold ------
       0.03   14.3   0.4       0.03   14.3   0.4    1.9  2  SPX        SPX domain


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.4   0.0   7.5e-22   6.7e-18       4      94 ..      86     175 ..      83     177 .. 0.93
   2 !   65.5   0.0   3.5e-22   3.1e-18       5      92 ..     182     274 ..     180     277 .. 0.91
   3 !   67.2   1.2     1e-22   9.1e-19       3      93 ..     284     432 ..     282     436 .. 0.84

  Alignments for each domain:
  == domain 1  score: 64.4 bits;  conditional E-value: 7.5e-22
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHH.HGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
   Mito_carr   4 svlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGl.rglyrGllpnllrvapasalkfvlyetlkrlll 94 
                 ++l+++laGg++g+ + ++++ ld+vKtr q +++     +s  +   + ki++eeG+ rgly+G++p+l++++p +++ f++ye  kr++ 
  EEA22492.1  86 PYLHSMLAGGIGGSSGDMLMHSLDTVKTRQQGDPHIPPRYGS--TSASYIKIFREEGFrRGLYSGVSPALMGSFPGTVIFFGTYEWSKRHMI 175
                 68899******************************9887555..8999**********899***************************9875 PP

  == domain 2  score: 65.5 bits;  conditional E-value: 3.5e-22
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSS.....HHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   5 vlkellaGglagavatlvttPldvvKtrlqtqkksskksksaa.....ildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrl 92 
                 +l++l aG +a ++a++v  P +v+Ktrlq+q++ ++   +++     + d++++i+++eG+ ++++G+ ++++r  p sal+f++ye+ +++
  EEA22492.1 182 TLSYLSAGFIADLAASVVYVPSEVLKTRLQLQGRYNNPYFKSGynyrgTGDAFRTIVRTEGFGAMFSGYKATIFRDLPFSALQFAFYEQEQEW 274
                 678899**************************9998765555578899****************************************97765 PP

  == domain 3  score: 67.2 bits;  conditional E-value: 1e-22
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH....................................CCCSSTTTSCSS.................. CS
   Mito_carr   3 lsvlkellaGglagavatlvttPldvvKtrlqt....................................qkksskksksaa.................. 47 
                 +++  e+l++ +ag +a+++t+PldvvKtr+qt                                    +          +                  
  EEA22492.1 284 IGLPLEILTATTAGGMAGVLTCPLDVVKTRIQTqqnpdaflqksstqaslsskkdsrphaqhsqhtsssS----------Slssskthsrpistsspst 372
                 6677799**************************9999999999999888888888877776665554441..........0344455556677788888 PP

                 ..............HHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr  48 ..............ildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrll 93 
                               ++  l+ iyk+eGl+g +rG++p+ ++++++s+ ++v+y++l + l
  EEA22492.1 373 stpqpgapilhtssVFTGLRLIYKTEGLAGWFRGVGPRAVWTSVQSGTMLVMYQYLLKKL 432
                 8888899***********************************************998876 PP

>> SPX  SPX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.4     0.031   2.8e+02     254     296 ..      20      62 ..       5     139 .. 0.61
   2 ?   14.3   0.4   3.3e-06      0.03      93     155 ..     316     376 ..     197     389 .. 0.79

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.031
         SPX 254 fessreldrgelseeardkevseelekngwikptksklekkrn 296
                 ++ss+++ rg+++++a++ +++e+  ++ + ++  +++++++ 
  EEA22492.1  20 STSSSSSFRGNHRHDATQLNNAEDTGSRTILQQLVNRKSSSEA 62 
                 2222222222222222222222222222222222222222111 PP

  == domain 2  score: 14.3 bits;  conditional E-value: 3.3e-06
         SPX  93 slprrsplsrssrssssygglvssppsansssssddssesnpadssssssssesessssssps 155
                 ++++ +   ++s+++ s ++++ s p+a++s+++++ss+ +  +s++ s++ +++s+s+s+p+
  EEA22492.1 316 TQQNPDAFLQKSSTQASLSSKKDSRPHAQHSQHTSSSSSLS--SSKTHSRPISTSSPSTSTPQ 376
                 67777788888888889999999999999999888888888..44444444444444444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (444 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       856  (0.0477439); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.32s 00:00:00.90 Elapsed: 00:00:00.46
# Mc/sec: 2892.35
//
Query:       EEA22493.1  [L=354]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (354 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       941  (0.0524848); expected 358.6 (0.02)
Passed bias filter:                      478  (0.0266607); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2555.14
//
Query:       EEA22494.1  [L=308]
Description: thiamine pyrophosphokinase Thi80, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.3e-27   96.2   0.0    8.8e-27   93.5   0.0    2.3  2  TPK_catalytic   Thiamin pyrophosphokinase, catalytic domain
    2.8e-17   62.2   0.0    4.5e-17   61.5   0.0    1.3  1  TPK_B1_binding  Thiamin pyrophosphokinase, vitamin B1 binding


Domain annotation for each model (and alignments):
>> TPK_catalytic  Thiamin pyrophosphokinase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   93.5   0.0   9.8e-31   8.8e-27       5     114 ..      37     180 ..      33     188 .. 0.85
   2 ?    1.1   0.0     0.043   3.8e+02      28      70 ..     181     225 ..     171     306 .. 0.65

  Alignments for each domain:
  == domain 1  score: 93.5 bits;  conditional E-value: 9.8e-31
  TPK_catalytic   5 wknaslrvcaDgGanrly...eeekerlellpdvivGDlDSirpevkefyeskgteivkkpdqdstDlekaialvlekekedk............. 84 
                      +a +++ aDgGanr+y   ++++ ++  lp+ i+GDlDSi+p+v+ +y+s+ ++i+++pd++stD++k+i++++ + +                
     EEA22494.1  37 RRHACYTLLADGGANRYYdlmKSRNIENIDLPSCILGDLDSIHPHVLAHYKSHHVPILHDPDEYSTDFTKCIRFLRAHAH--Ailsqenptvgmgd 130
                    578999************9987778888889*****************************************77777763..23355667778888 PP

  TPK_catalytic  85 ....................nksivvlgalggRfDhtlaninvllklkkk 114
                                        + +ivvlg+lggR+D+ +++ ++l+ + ++
     EEA22494.1 131 nhdlymtshptpasatgkkgQLDIVVLGGLGGRVDQGFSQAHHLYAAYEE 180
                    88888888888888888888*************************98443 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.043
  TPK_catalytic  28 rlellpdvivGDlDSirpevkefyeskgteivkkp..dqdstDle 70 
                    +++       GDl  +++e ++f+   g +++++p  +q+  D +
     EEA22494.1 181 KRKEASTSQAGDLYLLSEESLSFILPPGKNVIHTPftHQQRPDYQ 225
                    444444556788888888888888888888888887666666655 PP

>> TPK_B1_binding  Thiamin pyrophosphokinase, vitamin B1 binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.5   0.0     5e-21   4.5e-17      11      67 ..     229     288 ..     210     293 .. 0.82

  Alignments for each domain:
  == domain 1  score: 61.5 bits;  conditional E-value: 5e-21
                     T....B.-EEEEEESSSSEEEEEEESBSS-EEEEEESTTCETEEEEEBS.SSEEEEEEESB CS
  TPK_B1_binding  11 q....egkyvgliPlggevtglttkGlkwnledwelefggllstSNeveeeeeavtietds 67 
                     +    + ++vg+iPl +++t +++kG++w+++dw +e+gg+lstSN++++++  v++++d+
      EEA22494.1 229 EgkeiFSENVGIIPL-SGPTLISLKGFEWDVTDWRTEIGGQLSTSNHIRADKLEVHVDVDT 288
                     04555999*******.7999*****************************887666666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (308 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       321  (0.017904); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 2204.84
//
Query:       EEA22495.1  [L=252]
Description: thiamine pyrophosphokinase Thi80, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.6e-22   78.0   0.0    5.4e-21   74.9   0.0    2.5  2  TPK_catalytic   Thiamin pyrophosphokinase, catalytic domain
      2e-17   62.7   0.0    3.1e-17   62.0   0.0    1.3  1  TPK_B1_binding  Thiamin pyrophosphokinase, vitamin B1 binding


Domain annotation for each model (and alignments):
>> TPK_catalytic  Thiamin pyrophosphokinase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.9   0.0   6.1e-25   5.4e-21      31     114 ..      10     124 ..       2     131 .. 0.84
   2 ?    0.1   0.0     0.085   7.7e+02      43      70 ..     140     169 ..     128     250 .. 0.50

  Alignments for each domain:
  == domain 1  score: 74.9 bits;  conditional E-value: 6.1e-25
  TPK_catalytic  31 llpdvivGDlDSirpevkefyeskgteivkkpdqdstDlekaialvlekekedk.................................nksivvlga 93 
                     lp+ i+GDlDSi+p+v+ +y+s+ ++i+++pd++stD++k+i++++ + +                                    + +ivvlg+
     EEA22495.1  10 DLPSCILGDLDSIHPHVLAHYKSHHVPILHDPDEYSTDFTKCIRFLRAHAH--AilsqenptvgmgdnhdlymtshptpasatgkkgQLDIVVLGG 103
                    579****************************************77777763..2335566777888888888888888888888888********* PP

  TPK_catalytic  94 lggRfDhtlaninvllklkkk 114
                    lggR+D+ +++ ++l+ + ++
     EEA22495.1 104 LGGRVDQGFSQAHHLYAAYEE 124
                    ****************98443 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.085
  TPK_catalytic  43 irpevkefyeskgteivkkp..dqdstDle 70 
                    +++e ++f+   g +++++p  +q+  D +
     EEA22495.1 140 LSEESLSFILPPGKNVIHTPftHQQRPDYQ 169
                    555555555555555555555444444443 PP

>> TPK_B1_binding  Thiamin pyrophosphokinase, vitamin B1 binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.0   0.0   3.5e-21   3.1e-17      11      67 ..     173     232 ..     154     237 .. 0.82

  Alignments for each domain:
  == domain 1  score: 62.0 bits;  conditional E-value: 3.5e-21
                     T....B.-EEEEEESSSSEEEEEEESBSS-EEEEEESTTCETEEEEEBS.SSEEEEEEESB CS
  TPK_B1_binding  11 q....egkyvgliPlggevtglttkGlkwnledwelefggllstSNeveeeeeavtietds 67 
                     +    + ++vg+iPl +++t +++kG++w+++dw +e+gg+lstSN++++++  v++++d+
      EEA22495.1 173 EgkeiFSENVGIIPL-SGPTLISLKGFEWDVTDWRTEIGGQLSTSNHIRADKLEVHVDVDT 232
                     04556999*******.7999*****************************887666666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (252 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       344  (0.0191868); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 1748.94
//
Query:       EEA22496.1  [L=462]
Description: mitochondrial carrier protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.6e-42  142.7   0.6    1.8e-13   50.2   0.0    3.4  3  Mito_carr  Mitochondrial carrier protein
  ------ inclusion threshold ------
      0.073   13.1   0.0       0.16   12.0   0.0    1.5  1  DUF1179    Protein of unknown function (DUF1179)


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.2   0.0     2e-17   1.8e-13       3      91 ..      44     146 ..      42     152 .. 0.82
   2 !   38.8   0.0   7.3e-14   6.6e-10       4      93 ..     164     251 ..     162     255 .. 0.92
   3 !   50.2   0.2   2.1e-17   1.9e-13       4      93 ..     261     355 ..     258     358 .. 0.93

  Alignments for each domain:
  == domain 1  score: 50.2 bits;  conditional E-value: 2e-17
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.............CCCSSTTTSCSS..........HHHHHHHHHH.HHHHHGGGTTHHHHHHHHHH CS
   Mito_carr   3 lsvlkellaGglagavatlvttPldvvKtrlqt.............qkksskksksaa..........ildvlkkiyk.eeGlrglyrGllpnllrvap 77 
                 l++l + +aG+++ av+ ++t+Pl ++ trlq+             +          +          + d+ +kiy  e G+rg++ G++    +++ 
  EEA22496.1  44 LPALGHAVAGAAGSAVSNIATYPLKLIVTRLQMqrlaarkreltsdS----------KetnkptgyasVQDAAQKIYVtEGGIRGFFTGVGDDTWKTIA 132
                 5778999**************************55555555555444..........04555555566*********626789**************** PP

                 HHHHHHHHHHHHHH CS
   Mito_carr  78 asalkfvlyetlkr 91 
                  s+l f++y  l++
  EEA22496.1 133 DSFLFFLAYTILRE 146
                 *********98876 PP

  == domain 2  score: 38.8 bits;  conditional E-value: 7.3e-14
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   4 svlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrll 93 
                 ++l el++G laga+++l ttPl  + +r qt++   +++   ++ +v  +i  e+Gl g+++G++ +l+ +  + +++f+l+e l+ ll
  EEA22496.1 164 PILDELAIGILAGAFSKLWTTPLANIVIRKQTAALDDQSQPT-STKEVAARIKDEKGLIGFWSGYSETLVLTL-NPSITFFLNELLRYLL 251
                 67899***************************9999887554.49**************************99.**********998777 PP

  == domain 3  score: 50.2 bits;  conditional E-value: 2.1e-17
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSS.....HHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   4 svlkellaGglagavatlvttPldvvKtrlqtqkksskksksaa.....ildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrll 93 
                 s++ ++l ++++ ava+ +t+P+ ++Ktr q++++ s+ +k ++     ++  l++i  eeG+ +ly Gl   +++ ++++++++++ + ++ ++
  EEA22496.1 261 SATVTFLLAAISRAVASAITYPVSLAKTRAQADSSLSQGKKPSNafacnLFTSLQTIAVEEGIGALYDGLFGEVFKGFISHGITMLTKDAVHSTI 355
                 667899****************************99999888889999****************************************9998766 PP

>> DUF1179  Protein of unknown function (DUF1179)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   1.8e-05      0.16      30      82 ..     378     436 ..     353     443 .. 0.91

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 1.8e-05
     DUF1179  30 kkkfedDgrvdLvpknvakvredivkesskqakP......taqtPPaktPlekkgdvee 82 
                 + +++ ++ +++  ++ +++ e++ ++ s+++ P      +++ PP   P e++++ +e
  EEA22496.1 378 RARLQAEEYAEVAREGAKEIAESVKDSVSSVTSPnvsvdmSSNAPPEYSPFEETNELAE 436
                 56788899999999999*******************999999************99877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (462 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       510  (0.0284455); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.25s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 3218.31
//
Query:       EEA22497.1  [L=385]
Description: C6 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0056   17.2   0.2     0.0056   17.2   0.2    2.0  2  MRC1      MRC1-like domain
  ------ inclusion threshold ------
       0.87   10.0   0.0       0.87   10.0   0.0    3.7  4  C1_2      C1 domain


Domain annotation for each model (and alignments):
>> MRC1  MRC1-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.2   6.3e-07    0.0056      83     129 ..      56     106 ..      46     115 .. 0.63
   2 ?   -2.3   0.3      0.65   5.9e+03      36      48 ..     142     154 ..     135     169 .. 0.60

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 6.3e-07
        MRC1  83 tGglRkrrrraggndldls..DsDdee...aelrrrkrrrrekkrkallede 129
                 + +lR+r++  + +++dl+  D+Dd++   +  +rr rrrr+ + + l e e
  EEA22497.1  56 SYNLRTRKAS-RWKEIDLDipDDDDDDdnyQPSKRRTRRRRAVQSQPLAEVE 106
                 5589988863.36777777775555553565555666666666666555544 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 0.65
        MRC1  36 ddaeleeliDdes 48 
                 dd+ ++e++D  s
  EEA22497.1 142 DDNGDDEMVDAPS 154
                 2335667777665 PP

>> C1_2  C1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   1.1      0.17   1.5e+03      18      25 ..     197     204 ..     184     211 .. 0.60
   2 ?   -0.1   0.0      0.14   1.2e+03      17      25 ..     241     249 ..     230     254 .. 0.78
   3 ?   10.0   0.0   9.7e-05      0.87       5      37 ..     272     312 ..     267     320 .. 0.79
   4 ?   -0.1   0.2      0.14   1.2e+03      17      29 ..     335     347 ..     329     350 .. 0.74

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.17
        C1_2  18 sfnCsaCg 25 
                  f+C+ C 
  EEA22497.1 197 GFPCDFCT 204
                 35666664 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.14
        C1_2  17 esfnCsaCg 25 
                  ++ C++C 
  EEA22497.1 241 PTRMCNVCA 249
                 5678****7 PP

  == domain 3  score: 10.0 bits;  conditional E-value: 9.7e-05
        C1_2   5 HpLtls...........kgedssesfnCsaCgrkidgffYsCse 37 
                 H+ +++           +g+ ++++ +Cs C ++    f++Cs+
  EEA22497.1 272 HTFNFQaafnslggrrlRGRRHQINEWCSFCINPA---FFRCST 312
                 7777777777777777779999*********9995...699985 PP

  == domain 4  score: -0.1 bits;  conditional E-value: 0.14
        C1_2  17 esfnCsaCgrkid 29 
                 + + C++C+  +d
  EEA22497.1 335 GLRLCQGCKARMD 347
                 5678999997765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (385 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       525  (0.0292822); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.23s 00:00:00.80 Elapsed: 00:00:00.45
# Mc/sec: 2555.32
//
Query:       EEA22498.1  [L=509]
Description: hypothetical protein PMAA_091280 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.025   14.7   0.0      0.063   13.5   0.0    1.7  1  CHDCT2    CHDCT2 (NUC038) domain


Domain annotation for each model (and alignments):
>> CHDCT2  CHDCT2 (NUC038) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   3.5e-06     0.063     113     169 ..     202     257 ..     160     258 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 3.5e-06
      CHDCT2 113 esaagnknanavlekvLnqleelLsdmkadvsrlpatlsrlrpvaeRLqmsersiLs 169
                 +++    ++++ le+vL+ lee ++   +dv +l   l +lr++ +RL+ se+++L+
  EEA22498.1 202 SAQRKRLEQQEKLERVLTDLEECVAACPTDV-KLQGKLLHLRTLQNRLEQSEHTVLK 257
                 333455567889******************9.69*******************9995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (509 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1120  (0.0624686); expected 358.6 (0.02)
Passed bias filter:                      483  (0.0269396); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.26s 00:00:00.91 Elapsed: 00:00:00.42
# Mc/sec: 3628.88
//
Query:       EEA22499.1  [L=686]
Description: protein phosphatase regulatory subunit Gac1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.5e-36  124.2   0.8    4.3e-36  123.5   0.8    1.4  1  CBM_21          Carbohydrate/starch-binding module (family 21
    3.6e-09   37.1   0.9    7.1e-09   36.1   0.9    1.4  1  CBM53           Starch/carbohydrate-binding module (family 53
  ------ inclusion threshold ------
        0.2   10.7   0.0       0.35    9.9   0.0    1.3  1  Complex1_49kDa  Respiratory-chain NADH dehydrogenase, 49 Kd s


Domain annotation for each model (and alignments):
>> CBM_21  Carbohydrate/starch-binding module (family 21)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.5   0.8   7.2e-40   4.3e-36       3     113 .]     342     452 ..     340     452 .. 0.98

  Alignments for each domain:
  == domain 1  score: 123.5 bits;  conditional E-value: 7.2e-40
      CBM_21   3 qeqkvllerlelskdkkvlvGlvaVknlafeKavavrytldnWktilevpaeyvksaeeslkenntdrFkFkiklknllnsekaklelcikYevneeey 101
                 ++q+v ler++ls d+k lvG+v V+nlaf+K+v  r+t+d Wkt++ev+aey+++++++++++ +drF F+ikl++ ++  +++l++ci+Y v ++ey
  EEA22499.1 342 KQQPVRLERVFLSPDHKNLVGVVSVANLAFQKHVVARFTVDYWKTVSEVTAEYNHDVRKKQAHHGFDRFDFSIKLSDITDLGSKTLQVCIRYIVAGQEY 440
                 799************************************************************************************************ PP

      CBM_21 102 WdnNegkNYevk 113
                 WdnN+++NY+++
  EEA22499.1 441 WDNNDSMNYQIQ 452
                 **********95 PP

>> CBM53  Starch/carbohydrate-binding module (family 53)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.1   0.9   1.2e-12   7.1e-09       2      80 ..     368     452 ..     364     453 .. 0.87

  Alignments for each domain:
  == domain 1  score: 36.1 bits;  conditional E-value: 1.2e-12
       CBM53   2 kvyYnkslakevtlhygfngWkssqdvamtks....assgdseedwfeatvtvpkea....seldfvfds..egeenWDNNngqnYkvp 80 
                 +++++k++     ++++++ Wk++++v++++     +++   + d+f +++++ +      ++l+ ++ +   g+e+WDNN+++nY+++
  EEA22499.1 368 NLAFQKHV----VARFTVDYWKTVSEVTAEYNhdvrKKQAHHGFDRFDFSIKLSDITdlgsKTLQVCIRYivAGQEYWDNNDSMNYQIQ 452
                 45555555....********************9*987778888**********9977899566*****559***************996 PP

>> Complex1_49kDa  Respiratory-chain NADH dehydrogenase, 49 Kd subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0   5.9e-05      0.35     107     171 ..     395     466 ..     391     485 .. 0.76

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 5.9e-05
                     TTTHHHHSS-SSGGGS------.......-SSBSHHHHHHHHHHHHHHHHHHHHHHHHT--.S-SB---TTT CS
  Complex1_49kDa 107 kyDlRkaepYeaYdeldfdvpv.......geegDvydRylvrveEmrqSlkIieqaleklpegpvlaedkkv 171
                     ++D+Rk++  +++d++df + +       +++  v  Ry+v  +E ++ ++ ++  ++ +++++++++dk+ 
      EEA22499.1 395 NHDVRKKQAHHGFDRFDFSIKLsditdlgSKTLQVCIRYIVAGQEYWDNNDSMNYQIQFVKSEKTKTSDKNQ 466
                     78*******************955555555555677788888888888877777777777777776666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (686 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       636  (0.0354733); expected 358.6 (0.02)
Passed bias filter:                      301  (0.0167884); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.45
# Mc/sec: 4538.49
//
Query:       EEA22500.1  [L=667]
Description: protein phosphatase regulatory subunit Gac1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.4e-36  124.3   0.8    4.1e-36  123.6   0.8    1.4  1  CBM_21          Carbohydrate/starch-binding module (family 21
    3.5e-09   37.1   0.9    6.8e-09   36.2   0.9    1.4  1  CBM53           Starch/carbohydrate-binding module (family 53
  ------ inclusion threshold ------
       0.19   10.8   0.0       0.34   10.0   0.0    1.3  1  Complex1_49kDa  Respiratory-chain NADH dehydrogenase, 49 Kd s


Domain annotation for each model (and alignments):
>> CBM_21  Carbohydrate/starch-binding module (family 21)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.6   0.8   6.9e-40   4.1e-36       3     113 .]     323     433 ..     321     433 .. 0.98

  Alignments for each domain:
  == domain 1  score: 123.6 bits;  conditional E-value: 6.9e-40
      CBM_21   3 qeqkvllerlelskdkkvlvGlvaVknlafeKavavrytldnWktilevpaeyvksaeeslkenntdrFkFkiklknllnsekaklelcikYevneeey 101
                 ++q+v ler++ls d+k lvG+v V+nlaf+K+v  r+t+d Wkt++ev+aey+++++++++++ +drF F+ikl++ ++  +++l++ci+Y v ++ey
  EEA22500.1 323 KQQPVRLERVFLSPDHKNLVGVVSVANLAFQKHVVARFTVDYWKTVSEVTAEYNHDVRKKQAHHGFDRFDFSIKLSDITDLGSKTLQVCIRYIVAGQEY 421
                 799************************************************************************************************ PP

      CBM_21 102 WdnNegkNYevk 113
                 WdnN+++NY+++
  EEA22500.1 422 WDNNDSMNYQIQ 433
                 **********95 PP

>> CBM53  Starch/carbohydrate-binding module (family 53)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2   0.9   1.1e-12   6.8e-09       2      80 ..     349     433 ..     345     434 .. 0.87

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 1.1e-12
       CBM53   2 kvyYnkslakevtlhygfngWkssqdvamtks....assgdseedwfeatvtvpkea....seldfvfds..egeenWDNNngqnYkvp 80 
                 +++++k++     ++++++ Wk++++v++++     +++   + d+f +++++ +      ++l+ ++ +   g+e+WDNN+++nY+++
  EEA22500.1 349 NLAFQKHV----VARFTVDYWKTVSEVTAEYNhdvrKKQAHHGFDRFDFSIKLSDITdlgsKTLQVCIRYivAGQEYWDNNDSMNYQIQ 433
                 45555555....********************9*987778888**********9977899566*****559***************996 PP

>> Complex1_49kDa  Respiratory-chain NADH dehydrogenase, 49 Kd subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   5.7e-05      0.34     107     171 ..     376     447 ..     372     466 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 5.7e-05
                     TTTHHHHSS-SSGGGS------.......-SSBSHHHHHHHHHHHHHHHHHHHHHHHHT--.S-SB---TTT CS
  Complex1_49kDa 107 kyDlRkaepYeaYdeldfdvpv.......geegDvydRylvrveEmrqSlkIieqaleklpegpvlaedkkv 171
                     ++D+Rk++  +++d++df + +       +++  v  Ry+v  +E ++ ++ ++  ++ +++++++++dk+ 
      EEA22500.1 376 NHDVRKKQAHHGFDRFDFSIKLsditdlgSKTLQVCIRYIVAGQEYWDNNDSMNYQIQFVKSEKTKTSDKNQ 447
                     78*******************955555555555677788888888888877777777777777776666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (667 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       864  (0.0481901); expected 358.6 (0.02)
Passed bias filter:                      446  (0.0248759); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.70u 0.33s 00:00:01.03 Elapsed: 00:00:00.50
# Mc/sec: 3997.98
//
Query:       EEA22501.1  [L=103]
Description: histone H4.2 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.4e-09   36.4   0.1    5.3e-09   36.2   0.1    1.2  1  CENP-T_C         Centromere kinetochore component CENP-T hist
    1.9e-05   25.1   0.2    2.2e-05   24.8   0.2    1.2  1  Histone          Core histone H2A/H2B/H3/H4
      5e-05   23.4   0.2    7.3e-05   22.9   0.2    1.3  1  TAF              TATA box binding protein associated factor (
    0.00012   22.3   0.1    0.00021   21.5   0.1    1.5  1  CBFD_NFYB_HMF    Histone-like transcription factor (CBF/NF-Y)
    0.00017   21.9   0.1    0.00023   21.5   0.1    1.3  1  CENP-S           CENP-S protein
     0.0038   17.3   0.0     0.0045   17.0   0.0    1.1  1  TFIID-31kDa      Transcription initiation factor IID, 31kD su
     0.0045   17.0   0.0     0.0054   16.7   0.0    1.2  1  Bromo_TP         Bromodomain associated
  ------ inclusion threshold ------
       0.05   13.4   0.2      0.061   13.1   0.2    1.0  1  UPF0137          Uncharacterised protein family (UPF0137)
      0.059   13.9   0.0       0.12   12.9   0.0    1.4  1  TFIID_20kDa      Transcription initiation factor TFIID subuni
      0.073   13.1   0.0      0.082   12.9   0.0    1.1  1  HIGH_NTase1_ass  Cytidyltransferase-related C-terminal region


Domain annotation for each model (and alignments):
>> CENP-T_C  Centromere kinetochore component CENP-T histone fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2   0.1     3e-12   5.3e-09      16      79 ..      33      96 ..      18      99 .. 0.86

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 3e-12
    CENP-T_C 16 lakrfakasgskaklekealkalekasdkffeqvgeDLeayakHagRKtidesDvilLmkrqrk 79
                 a r   ++g  +++++  ++    +++ f+e v +D  +y++Ha+RKt+ + Dv+  +krq++
  EEA22501.1 33 PAIRRLARRGGVKRISAMIYEETRGVLKSFLESVIRDAVTYTEHAKRKTVTSLDVVYALKRQGR 96
                4444444456778999**********************************************86 PP

>> Histone  Core histone H2A/H2B/H3/H4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.8   0.2   1.2e-08   2.2e-05      77     129 ..      40      92 ..      16      94 .. 0.86

  Alignments for each domain:
  == domain 1  score: 24.8 bits;  conditional E-value: 1.2e-08
                 TTSSSXEEXHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTXSEEXHHHHHHHHH CS
     Histone  77 sekedlrisaeavlalqealEallvelfeeAnllakhaKRvTitpkDiqlArr 129
                 +++  +risa+  +    +l+ +l+++  +A  +++haKR+T+t+ D+  A++
  EEA22501.1  40 RRGGVKRISAMIYEETRGVLKSFLESVIRDAVTYTEHAKRKTVTSLDVVYALK 92 
                 46778899999999999999****************************99987 PP

>> TAF  TATA box binding protein associated factor (TAF)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.2   4.1e-08   7.3e-05       6      66 .]      32      92 ..      27      92 .. 0.80

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 4.1e-08
                HHHHHHHHHHTT---B-HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-SSB-HHHHHHHH- CS
         TAF  6 kesvkviAeslGitnLsdeaaalLaedveyrlkeivqeaakfmrhskRqkLtvaDvdsALr 66
                k +++ +A   G++ +s+   ++    ++  l  ++++a+ +++h+kR++ t+ Dv +AL+
  EEA22501.1 32 KPAIRRLARRGGVKRISAMIYEETRGVLKSFLESVIRDAVTYTEHAKRKTVTSLDVVYALK 92
                5666677777777777766666666666777899*************************98 PP

>> CBFD_NFYB_HMF  Histone-like transcription factor (CBF/NF-Y) and archaeal histone
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.1   1.1e-07   0.00021       8      65 .]      35      91 ..      28      91 .. 0.87

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 1.1e-07
                   HHHHHHCCTTXS-B-HHHHHHHHHHHHHHHHHHHHHHHHHHCCTTSSCE-HHHHHHHH CS
  CBFD_NFYB_HMF  8 vkkImksdpdarkiakdAkeliaecveefieelaseAaeickkekrKtikaehiklAv 65
                   ++++ +   ++++i+    e    +++ f+e++ + A+ +++++krKt++  ++  A+
     EEA22501.1 35 IRRLARRG-GVKRISAMIYEETRGVLKSFLESVIRDAVTYTEHAKRKTVTSLDVVYAL 91
                   77777777.888888888888888999**************************98876 PP

>> CENP-S  CENP-S protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.1   1.3e-07   0.00023      41      73 ..      54      94 ..      21      97 .. 0.80

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 1.3e-07
      CENP-S 41 q........lenlakDLeaFakHAkRstittdDvlLlaRrn 73
                +        le++ +D  ++ +HAkR+t+t  Dv+  ++r+
  EEA22501.1 54 EtrgvlksfLESVIRDAVTYTEHAKRKTVTSLDVVYALKRQ 94
                444444444889999*******************9998885 PP

>> TFIID-31kDa  Transcription initiation factor IID, 31kD subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   0.0   2.5e-06    0.0045      14      70 ..      38      94 ..      31     101 .. 0.83

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 2.5e-06
  TFIID-31kDa 14 iLaslgvteyeerVvlqLldfayrytssvLedAkvlaehakkkevslddvrlAiqsr 70
                 + +  gv+ ++  +++    +   +  sv++dA ++ ehak+k+v+  dv  A++ +
   EEA22501.1 38 LARRGGVKRISAMIYEETRGVLKSFLESVIRDAVTYTEHAKRKTVTSLDVVYALKRQ 94
                 55666777777777788888888999************************9998865 PP

>> Bromo_TP  Bromodomain associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0     3e-06    0.0054      33      70 ..      56      93 ..      27      97 .. 0.89

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 3e-06
                HHHHHHHHHHHHHHHHHHHTTSS-SS--HHHHHHHHHH CS
    Bromo_TP 33 teiaqkYirelgeqaksfaehagRseptlkDvvltLqe 70
                +++++++++++ ++a  + eha R ++t  Dvv +L++
  EEA22501.1 56 RGVLKSFLESVIRDAVTYTEHAKRKTVTSLDVVYALKR 93
                78999*******************************97 PP

>> UPF0137  Uncharacterised protein family (UPF0137)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.2   3.4e-05     0.061     141     212 ..      23      94 ..      18      99 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 3.4e-05
     UPF0137 141 lkseveslPrqavYtLasRegslekkeeiienynGetktelleiirktfPlldtdrRqknlsekllellakl 212
                 l+ +++ + + a+  La R g  +    i e+ +G  k+ l ++ir  +  +++ +R++  s  ++  l++ 
  EEA22501.1  23 LRDNIQGITKPAIRRLARRGGVKRISAMIYEETRGVLKSFLESVIRDAVTYTEHAKRKTVTSLDVVYALKRQ 94 
                 788999******************************************************999999999776 PP

>> TFIID_20kDa  Transcription initiation factor TFIID subunit A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   6.7e-05      0.12      31      65 ..      60      94 ..      54      95 .. 0.94

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 6.7e-05
                 HHHHHHHHHHHHHHHHHTT-SEE-HHHHHHHHHHH CS
  TFIID_20kDa 31 ddFvesvtkfacklakhRksdklevrDiqlhlern 65
                   F esv+  a+    h k +++ + D+ + l+r+
   EEA22501.1 60 KSFLESVIRDAVTYTEHAKRKTVTSLDVVYALKRQ 94
                 57*******************************96 PP

>> HIGH_NTase1_ass  Cytidyltransferase-related C-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   4.6e-05     0.082      69     114 ..      25      68 ..      11      92 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 4.6e-05
  HIGH_NTase1_ass  69 erieGvsGtkireavvegnlekvkdmlPeetievlkeelendnple 114
                      + i+G++   ir+    g +++++ m+ eet  vlk++le+   ++
       EEA22501.1  25 DNIQGITKPAIRRLARRGGVKRISAMIYEETRGVLKSFLES--VIR 68 
                      679**********************************9975..444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (103 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       561  (0.0312901); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 683.65
//
Query:       EEA22502.1  [L=66]
Description: hypothetical protein PMAA_091310 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (66 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       657  (0.0366445); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.29s 00:00:00.71 Elapsed: 00:00:00.47
# Mc/sec: 421.98
//
Query:       EEA22503.1  [L=1173]
Description: GPI maturation protein (Bst1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.6e-89  297.1   0.0    1.5e-88  296.4   0.0    1.3  1  PGAP1          PGAP1-like protein
    1.9e-05   25.4   0.2    1.9e-05   25.4   0.2    2.1  2  Abhydrolase_6  Alpha/beta hydrolase family
    0.00021   21.2   0.0    0.00035   20.5   0.0    1.3  1  Palm_thioest   Palmitoyl protein thioesterase
     0.0015   18.2   3.0     0.0029   17.3   0.2    2.6  2  Abhydrolase_1  alpha/beta hydrolase fold
     0.0038   16.5   0.0     0.0075   15.6   0.0    1.4  1  Hydrolase_4    Serine aminopeptidase, S33
     0.0054   16.0   0.0     0.0098   15.1   0.0    1.3  1  LCAT           Lecithin:cholesterol acyltransferase
  ------ inclusion threshold ------
      0.022   14.3   0.0       0.05   13.1   0.0    1.5  1  DUF676         Putative serine esterase (DUF676)
      0.049   13.5   0.0       0.11   12.4   0.0    1.5  1  Abhydrolase_3  alpha/beta hydrolase fold


Domain annotation for each model (and alignments):
>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  296.4   0.0   6.6e-92   1.5e-88       2     231 .]     217     461 ..     216     461 .. 0.95

  Alignments for each domain:
  == domain 1  score: 296.4 bits;  conditional E-value: 6.6e-92
       PGAP1   2 lsGipVlFvpGnagsykqvrslAseaaeayqe...lrkllknqnkkeldfftvdfneelsaldGrtlldqaeylndaIkyIlsly........ssseke 89 
                 lsG+pVlF+pGnagsykqvrslA+ea++++q+    +k+     +++ldff vdfne++ a++G+t+ldqaey+n+a++yIlsly        + s ++
  EEA22503.1 217 LSGAPVLFLPGNAGSYKQVRSLAAEASRHFQDvisYDKDRLDAGTRNLDFFMVDFNEDMAAFHGQTILDQAEYVNEALAYILSLYhdpnrshrDPSLPD 315
                 79************************999999998777777788889*****************************************99887778899 PP

       PGAP1  90 ptsviliGHSmGGivaraaltlknyikqsvntiltlasPhalpplsfdkdilklyervnefwkkeleekek....lenvllvsitggirdsmvpaeyss 184
                 p+sviliGHSmGGivar++lt++ny+++svnti+t+++Pha+pp+sfd di++ y+++n++w+ ++ ++ +    l +v+l+si+gg rd +vp++yss
  EEA22503.1 316 PSSVILIGHSMGGIVARTVLTMANYQANSVNTIITMSAPHAKPPVSFDSDIVHTYKQINDYWRGAYLQEWAnnnpLWHVTLISIAGGARDNVVPSDYSS 414
                 ***************************************************************998877666788************************ PP

       PGAP1 185 leelvpstnglsvattsipkvwlsidhlaivwckqlrrvvarallev 231
                 l +lvp+t+g++v+t+sip+vw+++dhl+i+wc+q+r vv + l+ev
  EEA22503.1 415 LASLVPETHGFTVFTSSIPDVWVGTDHLSITWCDQFRKVVIKSLYEV 461
                 *****************************************999875 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.4   0.2   8.4e-09   1.9e-05       1     121 [.     222     379 ..     222     455 .. 0.61
   2 ?   -3.7   0.5       6.6   1.5e+04      68      95 ..    1093    1127 ..    1090    1139 .. 0.74

  Alignments for each domain:
  == domain 1  score: 25.4 bits;  conditional E-value: 8.4e-09
                    EEEE--GC.....GC.HHHHHHHHCCT...CEEEEE--TTS..TS-GGCS.....--HHH.........CHHHHHHHCCTT............... CS
  Abhydrolase_6   1 vlllHGagssassWl.vapLaallaag...vhvlapDlpGh..Grsdppp.....ldled.........ladlaalldelaa.............. 62 
                    vl+l+G     +s+  v++Laa ++++   v  +++D      G   ++       d+++         ++d+a++++e  a              
     EEA22503.1 222 VLFLPGNA---GSYKqVRSLAAEASRHfqdV--ISYDKDRLdaG---TRNldffmVDFNEdmaafhgqtILDQAEYVNEALAyilslyhdpnrshr 309
                    799**944...34845999999999994444..55666322222...1111122211111222122222366666666666677778888999999 PP

                    ......TTSEEEEEETCHHHHHHHHHHCC........EEEEES-..----TTTS----TTHHHHHHTT-C CS
  Abhydrolase_6  63 .....gggpvvlvGHSlGGalalaaapla......lvvgvlldppptalpagllaaalelllallallrl 121
                         ++  v+l+GHS+GG++a  ++  a      ++  + +++p   +p ++ ++++  +++ ++  r 
     EEA22503.1 310 dpslpDPSSVILIGHSMGGIVARTVLTMAnyqansVNTIITMSAPHAKPPVSFDSDIVHTYKQINDYWRG 379
                    9999899999**************6666689888644448888866444444433333333333332222 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 6.6
                     EEEEET..CHHHHHHHHHHCC.......EEEEES- CS
  Abhydrolase_6   68 vlvGHS..lGGalalaaapla.....lvvgvlldp 95  
                     +lvG+S  +G ++a ++ ++a      +v ++l++
     EEA22503.1 1093 CLVGYSalYGVSYAYLLHHVAnifsaWLVIIYLAS 1127
                     79999999998888888888876666555577776 PP

>> Palm_thioest  Palmitoyl protein thioesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5   0.0   1.5e-07   0.00035      61     104 ..     293     356 ..     221     415 .. 0.66

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 1.5e-07
  Palm_thioest  61 k...................lelangfhaiGfSQGglflRaliercddkkn.vrnlislggpqa 104
                   +                   l  ++ +++iG+S Gg+++R ++ + + + n v+++i++++p+a
    EEA22503.1 293 AlayilslyhdpnrshrdpsLPDPSSVILIGHSMGGIVARTVLTMANYQANsVNTIITMSAPHA 356
                   244444455556666666664457899*****************99888889***********8 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.2      0.84   1.9e+03     135     164 ..      41      82 ..      35     137 .. 0.70
   2 !   17.3   0.2   1.3e-06    0.0029      73     128 ..     317     377 ..     220     389 .. 0.69

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.84
                    HHHHHHHHHHHCCSCHHHHHHHHHHHHHH............H CS
  Abhydrolase_1 135 carnpagplladelaaleqrhrlvdalkf............p 164
                      +  + ++++ ++a++++ hrl + +++            +
     EEA22503.1  41 TDQALQSQIASTPVALTNSDHRLNNNNNSvvsprsrtssavR 82 
                    556777889999999999999998877445555443333331 PP

  == domain 2  score: 17.3 bits;  conditional E-value: 1.3e-06
                    SSEEEEEETHHHHHHHHHHHHH...GGGEEEEEEESE..CSSCCHHHHHHHHHHHHHHCHH CS
  Abhydrolase_1  73 dkltlvGhSmGGmialayaaey...perVkalvllga..idpaaslieaqrqqaksfpdff 128
                     +++l+GhSmGG +a++++ ++    ++V+ +++++a    p+ s++++  +  k+  d++
     EEA22503.1 317 SSVILIGHSMGGIVARTVLTMAnyqANSVNTIITMSAphAKPPVSFDSDIVHTYKQINDYW 377
                    4566***************999999************655555555555555555555555 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   3.4e-06    0.0075      77     114 ..     318     359 ..     306     393 .. 0.69

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 3.4e-06
  Hydrolase_4  77 plfllGhSmGGliallyl..lrypd.kvagli.lsaPalkik 114
                   ++l+GhSmGG++a ++l  ++y++ +v+ +i +saP  k++
   EEA22503.1 318 SVILIGHSMGGIVARTVLtmANYQAnSVNTIItMSAPHAKPP 359
                  689*************99765555546665551455555544 PP

>> LCAT  Lecithin:cholesterol acyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   4.4e-06    0.0098     121     162 ..     317     355 ..     313     361 .. 0.91

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 4.4e-06
        LCAT 121 kkvvliaHSmGnllvlyflkwveaeaWvdqhikafislgapl 162
                 + v+li+HSmG+ + +  l   + +a   + ++ +i ++ap 
  EEA22503.1 317 SSVILIGHSMGGIVARTVLTMANYQA---NSVNTIITMSAPH 355
                 679****************9988887...99*********96 PP

>> DUF676  Putative serine esterase (DUF676)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   2.2e-05      0.05      83     126 ..     321     355 ..     280     367 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2.2e-05
      DUF676  83 fvghSlGgliaraaiaklkekemtlkeaikglepvtfitlasPh 126
                 ++ghS+Gg++ar +++ ++ +++          + t it++ Ph
  EEA22503.1 321 LIGHSMGGIVARTVLTMANYQAN---------SVNTIITMSAPH 355
                 79**************7775544.........567999***999 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   4.8e-05      0.11      69     153 ..     315     390 ..     288     409 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 4.8e-05
                    TTCEEEEEEETHHHHHHHHHHHHHHHTT---EEEEEEESE-SSTSSTTSHHHHHCHHTTTSSSSCHHHHHHHH.HHHSSGGGGGST CS
  Abhydrolase_3  69 dpsrivlaGdSaGGnlaaavalrardegepkvagqvliyPvtdlertesesikkaeeladgplltraaldlfw.rlylpeadrddp 153
                    dps+++l G S GG  a  v+ +a  +  ++v++++ ++      ++   s+      +++ + t ++++ +w  +yl+e   ++p
     EEA22503.1 315 DPSSVILIGHSMGGIVARTVLTMANYQ-ANSVNTIITMSAPHAK-PP--VSF------DSDIVHTYKQINDYWrGAYLQEWANNNP 390
                    89*******************999998.6788888888874422.33..333......3346777777777773356665555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1173 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       799  (0.0445647); expected 358.6 (0.02)
Passed bias filter:                      400  (0.0223102); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.80u 0.32s 00:00:01.12 Elapsed: 00:00:00.50
# Mc/sec: 7117.44
//
Query:       EEA22504.1  [L=1174]
Description: GPI maturation protein (Bst1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.6e-89  297.1   0.0    1.5e-88  296.4   0.0    1.3  1  PGAP1          PGAP1-like protein
    1.9e-05   25.4   0.2    1.9e-05   25.4   0.2    2.1  2  Abhydrolase_6  Alpha/beta hydrolase family
    0.00021   21.2   0.0    0.00035   20.5   0.0    1.3  1  Palm_thioest   Palmitoyl protein thioesterase
     0.0015   18.2   3.0     0.0029   17.3   0.2    2.6  2  Abhydrolase_1  alpha/beta hydrolase fold
     0.0038   16.5   0.0     0.0075   15.6   0.0    1.4  1  Hydrolase_4    Serine aminopeptidase, S33
     0.0054   16.0   0.0     0.0098   15.1   0.0    1.3  1  LCAT           Lecithin:cholesterol acyltransferase
  ------ inclusion threshold ------
      0.022   14.3   0.0       0.05   13.1   0.0    1.5  1  DUF676         Putative serine esterase (DUF676)
      0.049   13.5   0.0       0.11   12.4   0.0    1.5  1  Abhydrolase_3  alpha/beta hydrolase fold


Domain annotation for each model (and alignments):
>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  296.4   0.0   6.6e-92   1.5e-88       2     231 .]     217     461 ..     216     461 .. 0.95

  Alignments for each domain:
  == domain 1  score: 296.4 bits;  conditional E-value: 6.6e-92
       PGAP1   2 lsGipVlFvpGnagsykqvrslAseaaeayqe...lrkllknqnkkeldfftvdfneelsaldGrtlldqaeylndaIkyIlsly........ssseke 89 
                 lsG+pVlF+pGnagsykqvrslA+ea++++q+    +k+     +++ldff vdfne++ a++G+t+ldqaey+n+a++yIlsly        + s ++
  EEA22504.1 217 LSGAPVLFLPGNAGSYKQVRSLAAEASRHFQDvisYDKDRLDAGTRNLDFFMVDFNEDMAAFHGQTILDQAEYVNEALAYILSLYhdpnrshrDPSLPD 315
                 79************************999999998777777788889*****************************************99887778899 PP

       PGAP1  90 ptsviliGHSmGGivaraaltlknyikqsvntiltlasPhalpplsfdkdilklyervnefwkkeleekek....lenvllvsitggirdsmvpaeyss 184
                 p+sviliGHSmGGivar++lt++ny+++svnti+t+++Pha+pp+sfd di++ y+++n++w+ ++ ++ +    l +v+l+si+gg rd +vp++yss
  EEA22504.1 316 PSSVILIGHSMGGIVARTVLTMANYQANSVNTIITMSAPHAKPPVSFDSDIVHTYKQINDYWRGAYLQEWAnnnpLWHVTLISIAGGARDNVVPSDYSS 414
                 ***************************************************************998877666788************************ PP

       PGAP1 185 leelvpstnglsvattsipkvwlsidhlaivwckqlrrvvarallev 231
                 l +lvp+t+g++v+t+sip+vw+++dhl+i+wc+q+r vv + l+ev
  EEA22504.1 415 LASLVPETHGFTVFTSSIPDVWVGTDHLSITWCDQFRKVVIKSLYEV 461
                 *****************************************999875 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.4   0.2   8.4e-09   1.9e-05       1     121 [.     222     379 ..     222     455 .. 0.61
   2 ?   -3.7   0.5       6.6   1.5e+04      68      95 ..    1094    1128 ..    1091    1140 .. 0.74

  Alignments for each domain:
  == domain 1  score: 25.4 bits;  conditional E-value: 8.4e-09
                    EEEE--GC.....GC.HHHHHHHHCCT...CEEEEE--TTS..TS-GGCS.....--HHH.........CHHHHHHHCCTT............... CS
  Abhydrolase_6   1 vlllHGagssassWl.vapLaallaag...vhvlapDlpGh..Grsdppp.....ldled.........ladlaalldelaa.............. 62 
                    vl+l+G     +s+  v++Laa ++++   v  +++D      G   ++       d+++         ++d+a++++e  a              
     EEA22504.1 222 VLFLPGNA---GSYKqVRSLAAEASRHfqdV--ISYDKDRLdaG---TRNldffmVDFNEdmaafhgqtILDQAEYVNEALAyilslyhdpnrshr 309
                    799**944...34845999999999994444..55666322222...1111122211111222122222366666666666677778888999999 PP

                    ......TTSEEEEEETCHHHHHHHHHHCC........EEEEES-..----TTTS----TTHHHHHHTT-C CS
  Abhydrolase_6  63 .....gggpvvlvGHSlGGalalaaapla......lvvgvlldppptalpagllaaalelllallallrl 121
                         ++  v+l+GHS+GG++a  ++  a      ++  + +++p   +p ++ ++++  +++ ++  r 
     EEA22504.1 310 dpslpDPSSVILIGHSMGGIVARTVLTMAnyqansVNTIITMSAPHAKPPVSFDSDIVHTYKQINDYWRG 379
                    9999899999**************6666689888644448888866444444433333333333332222 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 6.6
                     EEEEET..CHHHHHHHHHHCC.......EEEEES- CS
  Abhydrolase_6   68 vlvGHS..lGGalalaaapla.....lvvgvlldp 95  
                     +lvG+S  +G ++a ++ ++a      +v ++l++
     EEA22504.1 1094 CLVGYSalYGVSYAYLLHHVAnifsaWLVIIYLAS 1128
                     79999999998888888888876666555577776 PP

>> Palm_thioest  Palmitoyl protein thioesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5   0.0   1.5e-07   0.00035      61     104 ..     293     356 ..     221     415 .. 0.66

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 1.5e-07
  Palm_thioest  61 k...................lelangfhaiGfSQGglflRaliercddkkn.vrnlislggpqa 104
                   +                   l  ++ +++iG+S Gg+++R ++ + + + n v+++i++++p+a
    EEA22504.1 293 AlayilslyhdpnrshrdpsLPDPSSVILIGHSMGGIVARTVLTMANYQANsVNTIITMSAPHA 356
                   244444455556666666664457899*****************99888889***********8 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.2      0.85   1.9e+03     135     164 ..      41      82 ..      35     137 .. 0.70
   2 !   17.3   0.2   1.3e-06    0.0029      73     128 ..     317     377 ..     220     389 .. 0.69

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.85
                    HHHHHHHHHHHCCSCHHHHHHHHHHHHHH............H CS
  Abhydrolase_1 135 carnpagplladelaaleqrhrlvdalkf............p 164
                      +  + ++++ ++a++++ hrl + +++            +
     EEA22504.1  41 TDQALQSQIASTPVALTNSDHRLNNNNNSvvsprsrtssavR 82 
                    556777889999999999999998877445555443333331 PP

  == domain 2  score: 17.3 bits;  conditional E-value: 1.3e-06
                    SSEEEEEETHHHHHHHHHHHHH...GGGEEEEEEESE..CSSCCHHHHHHHHHHHHHHCHH CS
  Abhydrolase_1  73 dkltlvGhSmGGmialayaaey...perVkalvllga..idpaaslieaqrqqaksfpdff 128
                     +++l+GhSmGG +a++++ ++    ++V+ +++++a    p+ s++++  +  k+  d++
     EEA22504.1 317 SSVILIGHSMGGIVARTVLTMAnyqANSVNTIITMSAphAKPPVSFDSDIVHTYKQINDYW 377
                    4566***************999999************655555555555555555555555 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   3.4e-06    0.0075      77     114 ..     318     359 ..     306     393 .. 0.69

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 3.4e-06
  Hydrolase_4  77 plfllGhSmGGliallyl..lrypd.kvagli.lsaPalkik 114
                   ++l+GhSmGG++a ++l  ++y++ +v+ +i +saP  k++
   EEA22504.1 318 SVILIGHSMGGIVARTVLtmANYQAnSVNTIItMSAPHAKPP 359
                  689*************99765555546665551455555544 PP

>> LCAT  Lecithin:cholesterol acyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   4.4e-06    0.0098     121     162 ..     317     355 ..     313     361 .. 0.91

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 4.4e-06
        LCAT 121 kkvvliaHSmGnllvlyflkwveaeaWvdqhikafislgapl 162
                 + v+li+HSmG+ + +  l   + +a   + ++ +i ++ap 
  EEA22504.1 317 SSVILIGHSMGGIVARTVLTMANYQA---NSVNTIITMSAPH 355
                 679****************9988887...99*********96 PP

>> DUF676  Putative serine esterase (DUF676)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   2.2e-05      0.05      83     126 ..     321     355 ..     280     367 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2.2e-05
      DUF676  83 fvghSlGgliaraaiaklkekemtlkeaikglepvtfitlasPh 126
                 ++ghS+Gg++ar +++ ++ +++          + t it++ Ph
  EEA22504.1 321 LIGHSMGGIVARTVLTMANYQAN---------SVNTIITMSAPH 355
                 79**************7775544.........567999***999 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   4.8e-05      0.11      69     153 ..     315     390 ..     288     409 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 4.8e-05
                    TTCEEEEEEETHHHHHHHHHHHHHHHTT---EEEEEEESE-SSTSSTTSHHHHHCHHTTTSSSSCHHHHHHHH.HHHSSGGGGGST CS
  Abhydrolase_3  69 dpsrivlaGdSaGGnlaaavalrardegepkvagqvliyPvtdlertesesikkaeeladgplltraaldlfw.rlylpeadrddp 153
                    dps+++l G S GG  a  v+ +a  +  ++v++++ ++      ++   s+      +++ + t ++++ +w  +yl+e   ++p
     EEA22504.1 315 DPSSVILIGHSMGGIVARTVLTMANYQ-ANSVNTIITMSAPHAK-PP--VSF------DSDIVHTYKQINDYWrGAYLQEWANNNP 390
                    89*******************999998.6788888888874422.33..333......3346777777777773356665555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1174 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       810  (0.0451782); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.88u 0.29s 00:00:01.17 Elapsed: 00:00:00.46
# Mc/sec: 7733.30
//
Query:       EEA22505.1  [L=64]
Description: hypothetical protein PMAA_091330 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (64 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1370  (0.0764125); expected 358.6 (0.02)
Passed bias filter:                      617  (0.0344135); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.36u 0.28s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 475.23
//
Query:       EEA22506.1  [L=1065]
Description: translation elongation factor eEF-3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.7e-47  161.4   0.5    9.4e-24   84.5   0.1    3.9  2  ABC_tran        ABC transporter
    5.5e-29  100.1   0.5    5.5e-29  100.1   0.5    2.2  1  4HB             Four helical bundle domain
    1.1e-16   60.9   0.0    5.8e-06   25.9   0.0    3.6  3  SMC_N           RecF/RecN/SMC N terminal domain
    3.5e-15   56.6   1.0     0.0022   17.9   0.0    4.8  5  AAA_21          AAA domain, putative AbiEii toxin, Type IV TA
    6.1e-09   35.5   0.1     0.0041   16.8   0.0    2.6  2  AAA_29          P-loop containing region of AAA domain
    7.7e-09   36.3   5.9    0.00021   21.9   0.1    3.2  2  AAA_23          AAA domain
    2.2e-07   31.0   0.0     0.0017   18.2   0.0    3.0  2  RsgA_GTPase     RsgA GTPase
    1.1e-06   28.7   0.0     0.0064   16.6   0.0    2.8  2  MMR_HSR1        50S ribosome-binding GTPase
    1.7e-06   28.4   0.0      0.035   14.3   0.0    2.8  2  AAA_28          AAA domain
      4e-06   27.3   0.3       0.18   12.2   0.0    3.8  4  AAA_16          AAA ATPase domain
      5e-06   26.8   0.0      0.068   13.4   0.0    3.4  2  AAA_22          AAA domain
    7.2e-06   26.6   0.1       0.23   12.0   0.0    3.4  2  AAA_18          AAA domain
    1.8e-05   25.2   0.0       0.61   10.5   0.1    4.5  3  AAA             ATPase family associated with various cellula
      4e-05   23.8   0.4       0.17   11.9   0.0    3.4  2  DUF87           Helicase HerA, central domain
    4.6e-05   23.2   0.0      0.062   13.0   0.0    2.8  2  PduV-EutP       Ethanolamine utilisation - propanediol utilis
    7.3e-05   22.9   0.1     0.0086   16.2   0.0    3.2  2  Dynamin_N       Dynamin family
    8.4e-05   22.4   1.2       0.37   10.5   0.1    3.1  3  AAA_15          AAA ATPase domain
    0.00014   21.5   0.0       0.11   12.1   0.0    2.6  2  AAA_27          AAA domain
    0.00026   21.0   0.0       0.17   11.8   0.0    2.6  2  NACHT           NACHT domain
    0.00026   21.3   0.0       0.96    9.9   0.0    2.8  2  RNA_helicase    RNA helicase
    0.00027   20.2   0.1        1.4    8.0   0.0    3.2  3  G-alpha         G-protein alpha subunit
    0.00028   19.9   0.1       0.71    8.8   0.0    2.7  2  MeaB            Methylmalonyl Co-A mutase-associated GTPase M
    0.00053   20.2   0.0       0.98    9.6   0.0    3.1  2  AAA_33          AAA domain
     0.0014   18.7   0.0        3.1    7.9   0.0    3.2  2  AAA_14          AAA domain
     0.0014   18.4   0.0        2.3    7.9   0.0    3.2  3  AAA_30          AAA domain
     0.0015   18.3   0.0        1.7    8.3   0.0    2.7  2  AAA_24          AAA domain
     0.0045   17.2   0.0        1.4    9.2   0.0    3.1  2  SbcCD_C         Putative exonuclease SbcCD, C subunit
     0.0067   16.8   0.2        5.5    7.5   0.4    3.2  2  HEAT_2          HEAT repeats
     0.0093   15.8   0.1        4.9    6.8   0.0    2.7  2  ATP_bind_1      Conserved hypothetical ATP binding protein
  ------ inclusion threshold ------
       0.01   16.1   0.0        7.3    6.8   0.0    2.6  2  Roc             Ras of Complex, Roc, domain of DAPkinase
      0.011   15.4   0.1        9.5    5.8   0.0    3.2  3  cobW            CobW/HypB/UreG, nucleotide-binding domain
      0.011   15.5   0.0        1.1    9.0   0.0    3.2  2  CLP1_P          mRNA cleavage and polyadenylation factor CLP1
      0.012   14.8   0.1       0.42    9.7   0.0    2.6  2  NB-ARC          NB-ARC domain
      0.013   15.7   0.0         17    6.0   0.0    3.3  2  HEAT            HEAT repeat
      0.015   15.1   0.1        2.4    7.9   0.0    2.3  2  MukB            MukB N-terminal
      0.024   14.1   0.0          4    6.9   0.0    2.4  2  AAA_7           P-loop containing dynein motor region
      0.026   14.3   0.0         12    5.6   0.0    2.8  2  IstB_IS21       IstB-like ATP binding protein
      0.027   14.4   0.0        2.4    8.0   0.0    2.6  2  Rad17           Rad17 P-loop domain
      0.033   12.7   0.2        1.2    7.6   0.0    2.6  2  Adaptin_N       Adaptin N terminal region
      0.048   13.4   0.0        8.6    6.0   0.0    2.6  2  Cytidylate_kin  Cytidylate kinase
      0.052   13.1   0.1        3.8    7.0   0.0    3.0  2  AAA_25          AAA domain
      0.067   13.1   2.2        2.6    7.9   0.0    3.1  2  ATPase_2        ATPase domain predominantly from Archaea
      0.072   13.1   0.0         19    5.3   0.0    3.4  2  AAA_5           AAA domain (dynein-related subfamily)
      0.077   12.4   0.3          5    6.5   0.0    3.1  2  Mg_chelatase    Magnesium chelatase, subunit ChlI
       0.08   12.8   0.0         12    5.8   0.0    2.4  2  Ploopntkinase3  P-loop Nucleotide Kinase3
      0.087   11.4   4.6        1.7    7.2   0.0    3.1  4  AAA_13          AAA domain
      0.097   12.3   0.0         11    5.7   0.0    2.5  2  ATP-synt_ab     ATP synthase alpha/beta family, nucleotide-bi
        0.1   11.8   0.0         11    5.1   0.0    2.5  2  DUF815          Protein of unknown function (DUF815)


Domain annotation for each model (and alignments):
>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.8   0.1   2.1e-22   7.7e-20       1     137 []     464     595 ..     464     595 .. 0.72
   2 !   84.5   0.1   2.5e-26   9.4e-24       2     137 .]     708     948 ..     707     948 .. 0.72

  Alignments for each domain:
  == domain 1  score: 71.8 bits;  conditional E-value: 2.1e-22
                 EEEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--...SEEEEEET..TCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHHHHHTCHHHHHHHSTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran   1 lknvslklkegekvaivGenGaGKStLlkllagllkp...teGeilld..gkdlkeqeleslrkeigvlpqepqlfpeltvrenesdeeiekalsklgl 94 
                 l++ +l lk+g++++++G+nG+GKStL++++ ++      ++ e++    ++dl+       +  ig+ +++       +v+ n  ++eie+ l ++g 
  EEA22506.1 464 LNQTHLRLKRGQRYGLLGPNGSGKSTLMRAINNEQVEgfpKKSEVKTVfvEHDLDA--ADTEQTVIGWTQKK-----LESVGINLPQKEIEAQLLEFGF 555
                 67889***************************998655555555522211233333..33333334433333.....2226667788888888888885 PP

                 GGTTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  95 kelkdtvvksspssLSgGqkqrvalarallkkpkllllDEpta 137
                  +   +  ++  +sLSgG+k ++alara+++kp++lllDEpt+
  EEA22506.1 556 LQ---EQFENPITSLSGGWKMKLALARAVFEKPDILLLDEPTN 595
                 54...5555556******************************8 PP

  == domain 2  score: 84.5 bits;  conditional E-value: 2.5e-26
                 EEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEE.....................EETTCEGGG........B-HHHCCHCEEEE-SS--S- CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....................xxxxxxxxx........xxxxxxxxxxxxxxxxxxxx RF
    ABC_tran   2 knvslklkegekvaivGenGaGKStLlkllagllkpteGei.....................lldgkdlke........qeleslrkeigvlpqepqlf 71 
                 ++++++++ g+++a++G+nGaGKStL+++l+g+l pt+G++                     +ld++++++        +++e +++  +++++e    
  EEA22506.1 708 QDITFQVSLGSRIAVIGPNGAGKSTLVNVLTGELIPTAGDVyqheniriayikqhafahidnHLDKTPSEYiqwrfqtgEDRETMDRANKIVTEE---- 802
                 799**************************************877777777777666666666666666666655665555555555555555554.... PP

                 TTSBHHHH..............................................................................HHHTCHHHHHHHS CS
                 xxxxxxxx..............................................................................xxxxxxxxxxxxx RF
    ABC_tran  72 peltvren..............................................................................esdeeiekalskl 92 
                                                                                                       +            
  EEA22506.1 803 -------DekamdkiykiegtsrrvigihsrrkfknsyeyecsfalgdnigmknekwtpmstqdnawiprneilashakmvaevdqK------------ 882
                 .......044444444446679999*************************9999999999888877777776666666555544440............ PP

                 TTGG.......................TTCBGESTTS.GGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                 xxxx.......................xxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  93 glke.......................lkdtvvkssp.ssLSgGqkqrvalarallkkpkllllDEpta 137
                    e                       l+++ v++s  + LSgGq+++v+la++ +++p l++lDEpt+
  EEA22506.1 883 ---EalasgqfrplvrreieihcanfgLDAELVSHSRmRGLSGGQRVKVVLAACSWQRPHLIVLDEPTN 948
                 ...24444444444444444444444444444443334******************************8 PP

>> 4HB  Four helical bundle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.1   0.5   1.5e-31   5.5e-29       1      78 []     352     429 ..     352     429 .. 1.00

  Alignments for each domain:
  == domain 1  score: 100.1 bits;  conditional E-value: 1.5e-31
         4HB   1 GdietvlailkeilkskkkkvaekfepvleYiaAiAgqLiDekeidsaaWvenlkpyvtvivgekeakeivdelRkrA 78 
                 Gd++tv+ailkeil++k+k++++ +e++++Yi+AiAgqLiDek+++  +W+en++py+ +++ge++ak+++++lRkrA
  EEA22506.1 352 GDVATVSAILKEILEPKYKAQIAGCEATIDYISAIAGQLIDEKVVEVISWTENTTPYLVALIGEADAKSTAETLRKRA 429
                 9****************************************************************************9 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.1   0.00028       0.1      28      44 ..     478     494 ..     461     496 .. 0.84
   2 !   19.1   0.0   1.9e-06   0.00071      68     205 ..     497     629 ..     494     639 .. 0.80
   3 !   25.9   0.0   1.6e-08   5.8e-06      27     208 ..     720     986 ..     708     995 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00028
                 EEEESTTSSHHHHHHHH CS
                 xxxxxxxxxxxxxxxxx RF
       SMC_N  28 aivGpNGSGKsnlldAi 44 
                  ++GpNGSGKs l+ Ai
  EEA22506.1 478 GLLGPNGSGKSTLMRAI 494
                 589*************9 PP

  == domain 2  score: 19.1 bits;  conditional E-value: 1.9e-06
                 BTTCSSTTEEEEEEEEEETTEESSSSSSCEEEEEEEETTSEEEEEETTEEE-HHHHHHHHHCTT-S..TTCS-HHHHHHHHHHHHHHHHCCS--SEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  68 skekasvkkaeveitfdnedkklkiekeevsisrrvkrkgeseykingkevtkkevsellesagis..kelLSgGektLvalaLlfAiqkvkpaplyll 164
                 ++ + + kk ev+ +f ++d +   ++e+++i  + k+ ++  + + +ke++ + ++  + +++++  +++LSgG k    + L +A   +++  + ll
  EEA22506.1 497 EQVEGFPKKSEVKTVFVEHDLD-AADTEQTVIGWTQKKLESVGINLPQKEIEAQLLEFGFLQEQFEnpITSLSGGWK----MKLALARAVFEKPDILLL 590
                 5566788999******999998.889999999999999999888887777777766665555555522569****98....4555566677888899** PP

                 CTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC- CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 165 DeidaaLDeknvkkvaellkeksknaQfivislreemleka 205
                 De   +LD knv+ + ++l ++   +  i++s+++++l ++
  EEA22506.1 591 DEPTNHLDVKNVAWLEQYLINSP--CTSIIVSHDSKFLDNV 629
                 *******************9998..999******9999876 PP

  == domain 3  score: 25.9 bits;  conditional E-value: 1.6e-08
                 EEEEESTTSSHHHHHHHHHHHC....TT..TTTTTTCHCCCCCC--..BTTCSSTTEEEEEEEEEETTEESSSSSSCEEEEEEEETTSEEEEEETTEEE CS
                 xxxxxxxxxxxxxxxxxxxxxx....xxx.xxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  27 taivGpNGSGKsnlldAilFvL....Ger.sakklrseklsdlihk..skekasvkkaeveitfdnedkklkiekeevsisrrvkrkgeseykingkev 118
                  a++GpNG+GKs l++ +   L    G+  + +++r + +++  ++   ++ +++ + +++  f+  ++++++++ +  ++ + ++  +  yki+g++ 
  EEA22506.1 720 IAVIGPNGAGKSTLVNVLTGELiptaGDVyQHENIRIAYIKQHAFAhiDNHLDKTPSEYIQWRFQTGEDRETMDRANKIVTEEDEKAMDKIYKIEGTSR 818
                 589************99987772222322244567766666655556566677888889*****99999999999999999999999999****99887 PP

                 -HHHHHHHHHCTT-STT.................................................................................. CS
                 xxxxxxxxxxxxxxxxx.................................................................................. RF
       SMC_N 119 tkkevsellesagiske.................................................................................. 135
                 +   +++   + +++ +                                                                                  
  EEA22506.1 819 RVIGIHS---RRKFKNSyeyecsfalgdnigmknekwtpmstqdnawiprneilashakmvaevdqkealasgqfrplvrreieihcanfgldaelvsh 914
                 7666655...4455555556899**************************************************************************** PP

                 ....CS-HHHHHHHHHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHHHHHHHHHCTTSEEEEE-SSHHHCCC-.SCE CS
                 ....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxx RF
       SMC_N 136 ....lLSgGektLvalaLlfAiqkvkpaplyllDeidaaLDeknvkkvaellkeksknaQfivislreemleka.dkl 208
                      LSgG++    + +++A  + ++  l +lDe    LD     ++++ +k+ +    +++i++++e++e+  +++
  EEA22506.1 915 srmrGLSGGQR----VKVVLAACSWQRPHLIVLDEPTNYLDRDSLGALSKAIKTFE--GGVVIITHSREFTENLtEEV 986
                 **********9....57788888999999************************999..899********999983444 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.0   5.9e-06    0.0022       3      19 ..     478     494 ..     477     519 .. 0.86
   2 !   14.2   0.0   7.6e-05     0.028     233     299 ..     563     623 ..     534     627 .. 0.80
   3 !   12.1   0.0   0.00034      0.13       3      19 ..     721     737 ..     720     761 .. 0.80
   4 ?   -1.5   0.0       4.5   1.7e+03      36      84 ..     817     866 ..     810     874 .. 0.84
   5 ?    6.6   0.0     0.016         6     248     299 ..     930     976 ..     912     980 .. 0.78

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 5.9e-06
      AAA_21   3 vliGpNgsGKSnLLdal 19 
                 +l GpNgsGKS+L++a+
  EEA22506.1 478 GLLGPNGSGKSTLMRAI 494
                 699*************9 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 7.6e-05
      AAA_21 233 parelSdGtkrllalltallralkkgsllliDEpEngLHPkllrrllell..kelsrngaQviltTHSp 299
                 p+++lS G k  lal+ a+++ +   ++ll+DEp n+L+ k ++ l + l  + +++     i+++H+ 
  EEA22506.1 563 PITSLSGGWKMKLALARAVFEKP---DILLLDEPTNHLDVKNVAWLEQYLinSPCTS-----IIVSHDS 623
                 77888888888889999999877...**************99999876665655655.....7777765 PP

  == domain 3  score: 12.1 bits;  conditional E-value: 0.00034
      AAA_21   3 vliGpNgsGKSnLLdal 19 
                 ++iGpNg+GKS+L   l
  EEA22506.1 721 AVIGPNGAGKSTLVNVL 737
                 79***********8887 PP

  == domain 4  score: -1.5 bits;  conditional E-value: 4.5
      AAA_21  36 lsggggirkipslldlydpeipfefeieeflsqgvryryglrlersqv..e 84 
                 +++  gi + +++ ++y+ e +f+++++  ++++ +++   ++++ ++   
  EEA22506.1 817 SRRVIGIHSRRKFKNSYEYECSFALGDN-IGMKNEKWTPMSTQDNAWIprN 866
                 67778888999999**************.*********9999999999544 PP

  == domain 5  score: 6.6 bits;  conditional E-value: 0.016
      AAA_21 248 ltallralkkgsllliDEpEngLHPkllrrllellkelsrngaQviltTHSp 299
                 l+a+  +++   l+++DEp n L+   l  l + +k  +     v++ THS 
  EEA22506.1 930 LAACSWQRP--HLIVLDEPTNYLDRDSLGALSKAIKTFEG---GVVIITHSR 976
                 444444444..79**********************99988...9******96 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.0   1.1e-05    0.0041      16      43 ..     468     495 ..     463     496 .. 0.78
   2 !   15.8   0.1   2.3e-05    0.0087      16      43 ..     711     738 ..     706     748 .. 0.76

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 1.1e-05
      AAA_29  16 tieidlkgatlltGpsGsGKSTllDAiq 43 
                  +++++ + + l Gp+GsGKSTl+ Ai+
  EEA22506.1 468 HLRLKRGQRYGLLGPNGSGKSTLMRAIN 495
                 566664447889************9885 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 2.3e-05
      AAA_29  16 tieidlkgatlltGpsGsGKSTllDAiq 43 
                 t++++l + + ++Gp+G+GKSTl+  ++
  EEA22506.1 711 TFQVSLGSRIAVIGPNGAGKSTLVNVLT 738
                 55666666899************96555 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0     3e-05     0.011      24      40 ..     479     495 ..     465     517 .. 0.93
   2 !   21.9   0.1   5.5e-07   0.00021      23     120 ..     721     829 ..     706     884 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 3e-05
      AAA_23  24 ItGpNGaGKTTildAik 40 
                 + GpNG+GK+T+++Ai 
  EEA22506.1 479 LLGPNGSGKSTLMRAIN 495
                 68*************95 PP

  == domain 2  score: 21.9 bits;  conditional E-value: 5.5e-07
      AAA_23  23 lItGpNGaGKTTildAiklaLygetprlsrks...grgfeksdveiese...gkvkayveltfenkdgry.....trsiererelskkkgkttkkakle 110
                 +++GpNGaGK+T+++ ++  L   +++    +      ++++ ++  ++   ++ ++y++ +f++  +r+     ++++++e e++ +k  ++ ++ ++
  EEA22506.1 721 AVIGPNGAGKSTLVNVLTGELIPTAGDVYQHEnirIAYIKQHAFAHIDNhldKTPSEYIQWRFQTGEDREtmdraNKIVTEEDEKAMDKIYKIEGTSRR 819
                 567*************998888765544443334333555555552222555788999*****998888899999999999999999999999999999 PP

      AAA_23 111 lleideleqf 120
                  ++i  +++f
  EEA22506.1 820 VIGIHSRRKF 829
                 9988776665 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   0.0    0.0029       1.1      97     123 ..     471     498 ..     432     518 .. 0.78
   2 !   18.2   0.0   4.7e-06    0.0017      88     133 ..     705     751 ..     680     761 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0029
                  CTT.SEEEEECSTTSSHHHHHHHHCTT- CS
  RsgA_GTPase  97 lkd.ktsvlvGqSGvGKStLinallpel 123
                  lk  +   l+G+ G GKStL+ a+++e+
   EEA22506.1 471 LKRgQRYGLLGPNGSGKSTLMRAINNEQ 498
                  444478889***************9985 PP

  == domain 2  score: 18.2 bits;  conditional E-value: 4.7e-06
                  TTHHHHHHHCTT.SEEEEECSTTSSHHHHHHHHCTT-----S----- CS
  RsgA_GTPase  88 egleelkellkd.ktsvlvGqSGvGKStLinallpelelktgevsek 133
                   ++++++ +++  + ++++G+ G+GKStL+n+l++el    g+v ++
   EEA22506.1 705 PQIQDITFQVSLgSRIAVIGPNGAGKSTLVNVLTGELIPTAGDVYQH 751
                  566777777665578899*****************987777777655 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   0.0    0.0037       1.4       2      24 ..     477     499 ..     476     527 .. 0.80
   2 !   16.6   0.0   1.7e-05    0.0064       1      24 [.     719     742 ..     719     768 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0037
                 EEEEESTTSSHHHHHHHHHTSTE CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltgeka 24 
                  +++G   +GKStL++a+ +e++
  EEA22506.1 477 YGLLGPNGSGKSTLMRAINNEQV 499
                 5799**************99743 PP

  == domain 2  score: 16.6 bits;  conditional E-value: 1.7e-05
                 EEEEEESTTSSHHHHHHHHHTSTE CS
    MMR_HSR1   1 evaivGrpNvGKStLinaltgeka 24 
                 ++a++G   +GKStL+n ltge  
  EEA22506.1 719 RIAVIGPNGAGKSTLVNVLTGELI 742
                 69******************9843 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.0     0.001      0.37       4      52 ..     479     534 ..     476     553 .. 0.70
   2 !   14.3   0.0   9.5e-05     0.035       1      56 [.     719     782 ..     719     808 .. 0.65

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.001
      AAA_28   4 itGgestGKTtlleaLaar...gypvvpEaareileekl...akgedalpwv.edl 52 
                 ++G+ ++GK+tl++a++++   g+p   E+ + ++e+ l   ++++  + w+ ++l
  EEA22506.1 479 LLGPNGSGKSTLMRAINNEqveGFPKKSEVKTVFVEHDLdaaDTEQTVIGWTqKKL 534
                 79***************875778888899998888887754333333444554444 PP

  == domain 2  score: 14.3 bits;  conditional E-value: 9.5e-05
      AAA_28   1 kivitGgestGKTtlleaLaar.....gypvvpEaar.eileekl.akgedalpwv.edllafa 56 
                 +i+++G+ ++GK+tl++ L+ +     g ++ +E  r  ++++++ a   ++l+++  + ++ +
  EEA22506.1 719 RIAVIGPNGAGKSTLVNVLTGEliptaGDVYQHENIRiAYIKQHAfAHIDNHLDKTpSEYIQWR 782
                 79******************66444434445577777245566554444467777655555544 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       6.2   2.3e+03      79     107 ..      66     115 ..      48     160 .. 0.62
   2 ?   -1.8   0.0       9.7   3.6e+03      72     112 ..     299     349 ..     276     426 .. 0.70
   3 !    9.9   0.0    0.0024      0.91      29      73 ..     479     530 ..     463     592 .. 0.67
   4 !   12.2   0.0   0.00048      0.18      25      98 ..     718     780 ..     706     825 .. 0.68

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 6.2
      AAA_16  79 eellrqlldeaesaeleawrekleeala.....................a 107
                 e+l +ql ++++++++e++ e++++ ++                     a
  EEA22506.1  66 ESLKKQLSNKKDANARERAVEAIRAIAEhssvapgvephlvtllgptlnA 115
                 46777888887777777777777777775555555555444444444440 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 9.7
      AAA_16  72 laqalareellrqlldeaesaeleawrekleeala...........avpela 112
                 ++  +   +l+ +l+ ++e+ + +++rek ++al             +pe++
  EEA22506.1 299 IVASFLP-KLMPALNKNHETLADPEAREKTKQALDtlirvgdvkdgKIPEVS 349
                 6666655.78888888888888888888777777766666666666333333 PP

  == domain 3  score: 9.9 bits;  conditional E-value: 0.0024
      AAA_16  29 lsGesGvGKsslvrellralekd.......ggiflrgkcdqlesaipysala 73 
                 l G+ G+GKs+l+r++ ++  +        + +f++ + d  +++ + + ++
  EEA22506.1 479 LLGPNGSGKSTLMRAINNEQVEGfpkksevKTVFVEHDLDAADTEQTVIGWT 530
                 78*************9975444455555544555555555554444444444 PP

  == domain 4  score: 12.2 bits;  conditional E-value: 0.00048
      AAA_16  25 elvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipysalaqalareellrqlldeaesaeleawr 98 
                 + + ++G+ G GKs+lv+ l  +l  +     +g+  q+ ++i     + ++++ + ++ ++++++++  e+ +
  EEA22506.1 718 SRIAVIGPNGAGKSTLVNVLTGELIPT-----AGDVYQH-ENI----RIAYIKQ-HAFAHIDNHLDKTPSEYIQ 780
                 4588**************999877776.....3333333.221....2344433.5555555554444444444 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.0   0.00018     0.068      10      70 ..     479     540 ..     472     619 .. 0.70
   2 !    9.0   0.0    0.0042       1.6       8      29 ..     720     741 ..     716     783 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 0.00018
      AAA_22  10 vtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsst..sskdllrellralglelka 70 
                 + G+ G+GK+tl+r + ++ + e ++++ ++++vfv+   +   + +++  +  ++l++ + +
  EEA22506.1 479 LLGPNGSGKSTLMRAINNEQV-EGFPKKSEVKTVFVEHDLDAadTEQTVIGWTQKKLESVGIN 540
                 56****************975.45666677777766544444447777777777777665555 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.0042
      AAA_22   8 lvvtGesGtGKTtllrrlleql 29 
                 ++v+G+ G+GK+tl++ l+ +l
  EEA22506.1 720 IAVIGPNGAGKSTLVNVLTGEL 741
                 79************99887665 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.0   0.00061      0.23       3      44 ..     479     532 ..     478     552 .. 0.69
   2 !   10.6   0.0    0.0016      0.61       1      44 [.     720     761 ..     720     828 .. 0.56

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00061
      AAA_18   3 ltGtpGvGKttlakeLskrl..gf..........gvnlrdvakenglllevdpe 44 
                 l G+ G+GK+tl ++++++   gf          +++  d a  ++++++++++
  EEA22506.1 479 LLGPNGSGKSTLMRAINNEQveGFpkksevktvfVEHDLDAADTEQTVIGWTQK 532
                 78**************77743344885555555555555555555555555555 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.0016
      AAA_18   1 IlltGtpGvGKttlakeLskrlgfgvnlrdvakenglllevdpe 44 
                 I++ G+ G+GK+tl + L  +l      +dv +++++++ + ++
  EEA22506.1 720 IAVIGPNGAGKSTLVNVLTGEL--IPTAGDVYQHENIRIAYIKQ 761
                 89****************6665..33333333333333333333 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.0      0.99   3.7e+02      81     119 ..     222     260 ..     212     265 .. 0.86
   2 !   10.5   0.1    0.0016      0.61       3      46 ..     479     534 ..     477     593 .. 0.71
   3 ?    7.0   0.0      0.02       7.6       3      23 ..     722     747 ..     720     809 .. 0.77

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.99
                 HHHHHHHHHHHHHHHTTTSSSTEEEEEEESSGGGSTHHH CS
         AAA  81 eeervvnqLlteldgvkkkeskvivigatnrpdkldpal 119
                 + er +++L++ +++ ++  ++v ++gat+ + ++ ++ 
  EEA22506.1 222 DIERFIPELIKCISKPENVPETVHLLGATTFVTDVHEPT 260
                 5678999**********************9987777665 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.0016
                 EESSTTSSHHHHHHHHHHHH..........THEEEE..EETTTCSSSSTTHHHHHH CS
         AAA   3 lyGppGtGKTllakavakel..........gvefle..isgsellskyvgesekki 46 
                 l Gp G GK++l++a+ +e           ++ f+e  +++++  + ++g ++kk+
  EEA22506.1 479 LLGPNGSGKSTLMRAINNEQvegfpkksevKTVFVEhdLDAADTEQTVIGWTQKKL 534
                 78****************95443333222233354411333333344555555544 PP

  == domain 3  score: 7.0 bits;  conditional E-value: 0.02
                 EESSTTSSHHHHHHHHHHHH.....T CS
         AAA   3 lyGppGtGKTllakavakel.....g 23 
                 ++Gp G GK++l++ +  el     +
  EEA22506.1 722 VIGPNGAGKSTLVNVLTGELiptagD 747
                 89*************99997554440 PP

>> DUF87  Helicase HerA, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   0.0    0.0074       2.8      25      50 ..     476     504 ..     468     513 .. 0.81
   2 !   11.9   0.0   0.00046      0.17      23      48 ..     717     742 ..     704     750 .. 0.88

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0074
       DUF87  25 HlAilgsTGsGKSntvavLleelle...k 50 
                 + + lg  GsGKS++++ + +e +e   k
  EEA22506.1 476 RYGLLGPNGSGKSTLMRAINNEQVEgfpK 504
                 6689999************9999987542 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 0.00046
       DUF87  23 trHlAilgsTGsGKSntvavLleell 48 
                   ++A++g  G+GKS++v vL  el+
  EEA22506.1 717 GSRIAVIGPNGAGKSTLVNVLTGELI 742
                 6789******************9998 PP

>> PduV-EutP  Ethanolamine utilisation - propanediol utilisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.0     0.011       4.2       6      27 ..     479     500 ..     475     522 .. 0.86
   2 !   13.0   0.0   0.00017     0.062       3      52 ..     719     783 ..     717     835 .. 0.81

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.011
   PduV-EutP   6 liGkvgsGKttLtqalkgeelk 27 
                 l+G+ gsGK tL++a+++e+++
  EEA22506.1 479 LLGPNGSGKSTLMRAINNEQVE 500
                 89****************9975 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 0.00017
   PduV-EutP   3 killiGkvgsGKttLtqalkg..............eelkYkktqaiefsdeviD.tPGeylenrk 52 
                 +i +iG+ g+GK tL + l+g               ++ Y k  a  + d+ +D tP ey++ r 
  EEA22506.1 719 RIAVIGPNGAGKSTLVNVLTGeliptagdvyqhenIRIAYIKQHAFAHIDNHLDkTPSEYIQWRF 783
                 899******************9********999777899*************9989*****9884 PP

>> Dynamin_N  Dynamin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0      0.23        86       4      33 ..     480     511 ..     478     636 .. 0.61
   2 !   16.2   0.0   2.3e-05    0.0086       1      80 [.     720     807 ..     720     946 .. 0.61

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.23
                 EEBTTTTHHHHHHHHHTS--..S---SSS--- CS
   Dynamin_N   4 vGsqSsGKSSvlnaLlgedi..lprgpnptTr 33 
                 +G   sGKS+++ a+  e++  +p+++++ T 
  EEA22506.1 480 LGPNGSGKSTLMRAINNEQVegFPKKSEVKTV 511
                 68889**********99987444566666554 PP

  == domain 2  score: 16.2 bits;  conditional E-value: 2.3e-05
                 EEEEEBTTTTHHHHHHHHHTS--S---SSS---S-EEEEE...............CCT---CCS...SSEEEE..T-EB--CHHHHHHHHHHHHHHH CS
   Dynamin_N   1 iavvGsqSsGKSSvlnaLlgedilprgpnptTrrplelql...............geeeeaseravkeelkek..ekkledfsevreeieketekia 80 
                 iav+G   +GKS+++n L+ge i p+   +     + + +                        ++ ++++ +   ++ e +++ ++ +++e ek+ 
  EEA22506.1 720 IAVIGPNGAGKSTLVNVLTGELI-PTAGDVYQHENIRIAYikqhafahidnhldkT-------PSEYIQWR-FqtGEDRETMDRANKIVTEEDEKAM 807
                 89******************995.66666666666777773333333333333221.......11112222.1243333333333333333333333 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   0.0    0.0026      0.97      28      47 ..     479     495 ..     477     535 .. 0.69
   2 ?   -2.2   0.0       6.8   2.5e+03     322     336 ..     583     597 ..     533     611 .. 0.81
   3 !   10.5   0.1   0.00098      0.37      18     156 ..     713     841 ..     706    1051 .. 0.52

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0026
      AAA_15  28 liGkNnsGKSsilealdlFl 47 
                 l G+N+sGKS++++a+    
  EEA22506.1 479 LLGPNGSGKSTLMRAI---N 495
                 56**************...2 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 6.8
      AAA_15 322 eknvilliEEPEahL 336
                 ek++ill++EP +hL
  EEA22506.1 583 EKPDILLLDEPTNHL 597
                 4679*******9998 PP

  == domain 3  score: 10.5 bits;  conditional E-value: 0.00098
      AAA_15  18 eidlseeltvliGkNnsGKSsilealdlFlnnkekkn..............kkvikiekedleifeniseskdikIdvefaekekakeyektlkskekk 102
                 +++l +    +iG+N++GKS+++++l          +                +  ++  + +i ++ ++  +  I+  f  +    e+     ++ ++
  EEA22506.1 713 QVSLGS-RIAVIGPNGAGKSTLVNVLT-----G---EliptagdvyqheniRIAYIKQHAFAHIDNHLDKTPSEYIQWRF--Q--TGEDR----ETMDR 794
                 566666.7899*************992.....2...11123344444555422223333444455555555566666666..1..11111....11111 PP

      AAA_15 103 kadlllkkkesdlkktikdkklklkknelsdekisvekkkskkelpkekeekle 156
                  +++ +++ e++++k++k + +           i ++ + + k+ ++++++++ 
  EEA22506.1 795 ANKIVTEEDEKAMDKIYKIEGTS-------RRVIGIHSRRKFKNSYEYECSFAL 841
                 11222222222222222222222.......344555555555555555555555 PP

>> AAA_27  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.1   0.0   0.00028      0.11      31      68 ..     479     517 ..     457     526 .. 0.81
   2 ?    6.5   0.0     0.015       5.8      30      46 ..     721     737 ..     707     742 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00028
      AAA_27  31 iyGpNEAGKstalrAis.dllfGipertkdnflhdakkL 68 
                 ++GpN +GKst++rAi+ + + G+p++++ + ++ +++L
  EEA22506.1 479 LLGPNGSGKSTLMRAINnEQVEGFPKKSEVKTVFVEHDL 517
                 47**************72567899999999998888877 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.015
      AAA_27  30 liyGpNEAGKstalrAi 46 
                  ++GpN AGKst+++ +
  EEA22506.1 721 AVIGPNGAGKSTLVNVL 737
                 489*********98765 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   0.0   0.00045      0.17       5      39 ..     479     513 ..     476     529 .. 0.91
   2 ?    6.3   0.0     0.022         8       2      20 ..     719     737 ..     718     767 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00045
                 EEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEE CS
       NACHT   5 lqGeaGsGKTtLlqklalawaegklpqgafklvFf 39 
                 l G++GsGK+tL++ +  +  eg +++ ++k vF+
  EEA22506.1 479 LLGPNGSGKSTLMRAINNEQVEGFPKKSEVKTVFV 513
                 68*****************9999999999999997 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.022
                 CEEEEC-TTTCHHHHHHHH CS
       NACHT   2 lvilqGeaGsGKTtLlqkl 20 
                  +++ G++G GK+tL+  l
  EEA22506.1 719 RIAVIGPNGAGKSTLVNVL 737
                 5899***********9876 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.3   0.0    0.0077       2.9       3      32 ..     479     506 ..     478     527 .. 0.75
   2 !    9.9   0.0    0.0026      0.96       2      35 ..     721     749 ..     720     775 .. 0.78

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.0077
  RNA_helicase   3 lyGpsgeGKStlakeLakallkklklkkkd 32 
                   l Gp+g GKStl++ + ++  + +  +kk+
    EEA22506.1 479 LLGPNGSGKSTLMRAINNEQVEGF--PKKS 506
                   57*************887766555..4444 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.0026
  RNA_helicase   2 wlyGpsgeGKStlakeLakallkklklkkkdsvy 35 
                    + Gp+g GKStl++ L+ +l      +++++vy
    EEA22506.1 721 AVIGPNGAGKSTLVNVLTGELI-----PTAGDVY 749
                   689*************998887.....4444444 PP

>> G-alpha  G-protein alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.72   2.7e+02      91     185 ..      52     250 ..      18     278 .. 0.59
   2 !    8.0   0.0    0.0036       1.4      10      54 ..     461     505 ..     453     690 .. 0.84
   3 !    7.5   0.0    0.0052       1.9      25     108 ..     719     805 ..     704     896 .. 0.74

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.72
                 HHC-SS-SCCCS-HCHHHH......................HHCCHHC-HCHHH............................................. CS
     G-alpha  91 lqelkerldplkkveasliaklssateee............qeiefnpraevge............................................. 132
                 +  ++e++ plk+ve+ + ++ls++++ +                        e                                             
  EEA22506.1  52 NGPIEEKIVPLKAVESLK-KQLSNKKDANareraveairaiA-----------Ehssvapgvephlvtllgptlnavgdkmtnvknaaqvaaialvkai 138
                 556777788888888764.45555544444333333333330...........2333333444444444444444444444444444444445555566 PP

                 .....................................................HHHHHC.CSHHHHHH.HCCGCCTT...--TTHHHHHCT.HHHHCST CS
     G-alpha 133 .....................................................dikaLw.ndpgiqel.yerrnkik...lednaeyFldd.leritsp 172
                                                                        +++w ++p +++  y   +ki    ++ ++e F+ + ++ i++p
  EEA22506.1 139 npnatkaalpsiinsilsaqkwpekmtglqciealvetapaqlaflvpdlipvVSESMWdTKPEVKKAaYGTMEKICgliVNKDIERFIPElIKCISKP 237
                 666666666666666666666666666666666666677777777777777766677775566666663444444444335677777777657777777 PP

                 T----CHHHHCS- CS
     G-alpha 173 dYlptddDilkar 185
                 + +p+  ++l a 
  EEA22506.1 238 ENVPETVHLLGAT 250
                 7777777777665 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0036
                 XXXXXXXXXXE..EEEEEEEESTTSSHHHHHHHHHHHCS----HH CS
     G-alpha  10 slkaerkarkkkrevkllllGqseSGKsTilkqlkllykkgfsee 54 
                 ++  +++  + kr  +  llG ++SGKsT+++ +     +gf ++
  EEA22506.1 461 KILLNQTHLRLKRGQRYGLLGPNGSGKSTLMRAINNEQVEGFPKK 505
                 556666666667788889**************9986666666655 PP

  == domain 3  score: 7.5 bits;  conditional E-value: 0.0052
                 EEEEEESTTSSHHHHHHHHH..HHCS--..--HHHHHCCHHHHHHHHHHHHHHHHHHHHHTT..........HHHC-SS-SCCCS-HCHHH CS
     G-alpha  25 kllllGqseSGKsTilkqlk..llykkg..fseeelatwraviqlnivrsiktilealesleselsesf...elqelkerldplkkveasl 108
                 ++ ++G ++ GKsT+++ l   l+ + g  +++e++++  a+i ++   +i++ l++  s+ ++   +f   e++e  +r++++ + e+++
  EEA22506.1 719 RIAVIGPNGAGKSTLVNVLTgeLIPTAGdvYQHENIRI--AYIKQHAFAHIDNHLDKTPSEYIQW--RFqtgEDRETMDRANKIVTEEDEK 805
                 8999***************9876666657788885555..8999*****9***999999977777..443355556666666665555543 PP

>> MeaB  Methylmalonyl Co-A mutase-associated GTPase MeaB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.8   0.0    0.0019      0.71      15      52 ..     460     497 ..     452     505 .. 0.89
   2 !    8.1   0.1    0.0032       1.2      19      54 ..     707     742 ..     686     748 .. 0.78

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0019
                 HHHHHHHHGGG-S-SEEEEEEE-TTSSHHHHHHHHHHH CS
        MeaB  15 akellerllakaGraqvvGltGvPGaGkstlvealgle 52 
                 ak ll++   +  r q+ Gl G  G+Gkstl+ a+  e
  EEA22506.1 460 AKILLNQTHLRLKRGQRYGLLGPNGSGKSTLMRAINNE 497
                 788999999999********************998765 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0032
                 HHHHGGG-S-SEEEEEEE-TTSSHHHHHHHHHHHHH CS
        MeaB  19 lerllakaGraqvvGltGvPGaGkstlvealglelr 54 
                 ++ ++ +     ++ + G  GaGkstlv+ l+ el+
  EEA22506.1 707 IQDITFQVSLGSRIAVIGPNGAGKSTLVNVLTGELI 742
                 5666666667789******************99987 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.0     0.017       6.3       5      20 ..     480     495 ..     479     538 .. 0.73
   2 !    9.6   0.0    0.0026      0.98       3      25 ..     721     746 ..     720     804 .. 0.59

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.017
      AAA_33   5 vGlpGsGKstlaerll 20 
                  G++GsGKstl + + 
  EEA22506.1 480 LGPNGSGKSTLMRAIN 495
                 6**********99754 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.0026
      AAA_33   3 llvGlpGsGKstlaerllkklg...a 25 
                  ++G++G+GKstl+  l  +l    +
  EEA22506.1 721 AVIGPNGAGKSTLVNVLTGELIptaG 746
                 589***********999777655542 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.9   0.0    0.0082       3.1       6      49 ..     478     523 ..     474     620 .. 0.85
   2 ?    7.2   0.0     0.014       5.1       5      47 ..     720     768 ..     717     829 .. 0.73

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0082
      AAA_14   6 vitGaRrvGKTtllkqlikell..vkkesilyinldderdkkladp 49 
                  + G+  +GK+tl++ + +e+    +k+s +   + ++++++++++
  EEA22506.1 478 GLLGPNGSGKSTLMRAINNEQVegFPKKSEVKTVFVEHDLDAADTE 523
                 588************9999998996666666555555555444433 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.014
      AAA_14   5 lvitGaRrvGKTtllkqlikell......vkkesilyinldderdkkla 47 
                 +++ G+  +GK+tl++ l  el+       ++e+i    ++++ ++ ++
  EEA22506.1 720 IAVIGPNGAGKSTLVNVLTGELIptagdvYQHENIRIAYIKQHAFAHID 768
                 6799**************9999998888755555544444444444333 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.9   0.0    0.0061       2.3      22      40 ..     478     496 ..     467     533 .. 0.85
   2 ?    6.1   0.0     0.022       8.3      21      45 ..     720     745 ..     707     806 .. 0.79
   3 ?   -0.8   0.0       2.8   1.1e+03      81     119 ..     921     970 ..     866     975 .. 0.68

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0061
      AAA_30  22 vltGpAGtGKttalkalre 40 
                  l Gp G+GK+t+++a+++
  EEA22506.1 478 GLLGPNGSGKSTLMRAINN 496
                 578*************954 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.022
      AAA_30  21 avltGpAGtGKttalkal.reaweaa 45 
                  ++ Gp G+GK+t++++l  e++ +a
  EEA22506.1 720 IAVIGPNGAGKSTLVNVLtGELIPTA 745
                 4689************9944555555 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 2.8
      AAA_30  81 k.........grarlepgtllivDEagmv.dtkqlaallkaaek.agakv 119
                           ++ ++++ +l++ DE     d ++l al ka+++ +g  v
  EEA22506.1 921 SggqrvkvvlAACSWQRPHLIVLDEPTNYlDRDSLGALSKAIKTfEGGVV 970
                 0555555666556788889******6654399999999999888334443 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.0      0.01       3.9       2      22 ..     474     494 ..     473     527 .. 0.83
   2 !    8.3   0.0    0.0045       1.7       3      22 ..     718     737 ..     716     800 .. 0.90

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.01
      AAA_24   2 klkiliyGpsgiGKTtlakel 22 
                 ++++ + Gp+g+GK+tl++ +
  EEA22506.1 474 GQRYGLLGPNGSGKSTLMRAI 494
                 67899*************987 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.0045
      AAA_24   3 lkiliyGpsgiGKTtlakel 22 
                  +i+++Gp+g+GK+tl++ l
  EEA22506.1 718 SRIAVIGPNGAGKSTLVNVL 737
                 589*************9866 PP

>> SbcCD_C  Putative exonuclease SbcCD, C subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.0      0.13        50      62      82 ..     583     603 ..     556     610 .. 0.70
   2 !    9.2   0.0    0.0037       1.4      26      89 ..     913     963 ..     889     964 .. 0.75

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.13
     SbcCD_C  62 palrlvfLDEAFsklDeesia 82 
                 +++++++LDE  + lD +++a
  EEA22506.1 583 EKPDILLLDEPTNHLDVKNVA 603
                 4589************99987 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.0037
     SbcCD_C  26 lsrssgtlSGGekqflaylalaaalaalyssaegrepalrlvfLDEAFsklDeesiatllelle 89 
                  ++++++lSGG++   + ++la    a  ++      ++ l++LDE  + lD +s+ +l ++++
  EEA22506.1 913 SHSRMRGLSGGQR---VKVVLA----ACSWQ------RPHLIVLDEPTNYLDRDSLGALSKAIK 963
                 5788899999999...666666....34444......689****************99988775 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   0.4     0.015       5.5       2      33 ..      66      97 ..      65     164 .. 0.76
   2 ?    4.9   0.0     0.095        36      30      74 ..     186     237 ..     161     243 .. 0.77

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.015
      HEAT_2  2 daLlqalendpdpevrraairaLgrignpeal 33
                + L ++l+n +d + r +a++a+  i++ +++
  EEA22506.1 66 ESLKKQLSNKKDANARERAVEAIRAIAEHSSV 97
                78999999999999999999999988765432 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.095
      HEAT_2  30 pealpaLvellededpavRraaaeaLgai......gd.pealpaLkellddd 74 
                 p+++p + e + d++p+v +aa  ++ +i      +d ++++p L ++   +
  EEA22506.1 186 PDLIPVVSESMWDTKPEVKKAAYGTMEKIcglivnKDiERFIPELIKCISKP 237
                 688999999999**************99864444434788999999887655 PP

>> ATP_bind_1  Conserved hypothetical ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.0   0.0     0.024       8.8       2      17 ..     480     495 ..     479     511 .. 0.89
   2 ?    6.8   0.0     0.013       4.9       1      17 [.     722     738 ..     722     753 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.024
  ATP_bind_1   2 vGpaGsGKttfvgals 17 
                 +Gp GsGK+t+++a++
  EEA22506.1 480 LGPNGSGKSTLMRAIN 495
                 7***********9986 PP

  == domain 2  score: 6.8 bits;  conditional E-value: 0.013
  ATP_bind_1   1 vvGpaGsGKttfvgals 17 
                 v+Gp G+GK+t+v+ l+
  EEA22506.1 722 VIGPNGAGKSTLVNVLT 738
                 89***********9875 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.0      0.02       7.3       4      37 ..     479     513 ..     476     535 .. 0.71
   2 ?    6.6   0.0     0.024       8.9       1      22 [.     719     740 ..     719     787 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.02
                 EESSTTSSHHHHHHCHCT-CCC-E.EETTTTEEEE CS
         Roc   4 lvGdsgvGKtsllkrfvedkfsek.ekstigvdfl 37 
                 l+G +g+GK++l++ + +++++   +ks +   f+
  EEA22506.1 479 LLGPNGSGKSTLMRAINNEQVEGFpKKSEVKTVFV 513
                 89**************9999874413334444444 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.024
                 EEEEESSTTSSHHHHHHCHCT- CS
         Roc   1 KvvlvGdsgvGKtsllkrfved 22 
                 ++ ++G +g+GK++l++ ++ +
  EEA22506.1 719 RIAVIGPNGAGKSTLVNVLTGE 740
                 5899************988754 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       3.5   1.3e+03      25      48 ..     279     302 ..     267     364 .. 0.74
   2 ?    5.8   0.0     0.026       9.5       4      22 ..     478     496 ..     476     538 .. 0.78
   3 ?    5.4   0.0     0.032        12       4      21 ..     721     738 ..     718     779 .. 0.74

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 3.5
                 -SS-EEEEESS-SSCHCCCCCCHC CS
        cobW  25 aglklavivNefgevsiDaellre 48 
                  ++k aviv ++ ++ +D +++++
  EEA22506.1 279 IKRKSAVIVDNMCKLVEDPQIVAS 302
                 468899999999999999999853 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.026
                 EEEESTTCCHHHHHHHHHC CS
        cobW   4 vltGflGsGKTtLlnhlle 22 
                 +l G+ GsGK+tL++++ +
  EEA22506.1 478 GLLGPNGSGKSTLMRAINN 496
                 5789**********99873 PP

  == domain 3  score: 5.4 bits;  conditional E-value: 0.032
                 EEEESTTCCHHHHHHHHH CS
        cobW   4 vltGflGsGKTtLlnhll 21 
                  + G+ G+GK+tL+n l+
  EEA22506.1 721 AVIGPNGAGKSTLVNVLT 738
                 6889**********9887 PP

>> CLP1_P  mRNA cleavage and polyadenylation factor CLP1 P-loop
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.0    0.0029       1.1       1      32 [.     481     517 ..     481     529 .. 0.80
   2 ?    2.6   0.0      0.27     1e+02       1      19 [.     724     742 ..     724     749 .. 0.88

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.0029
      CLP1_P   1 GpkdsGKSTlarlLlNyal.....rkgrkpvyvDlDv 32 
                 Gp+ sGKSTl+r + N+ +     +++ k+v+v+ D+
  EEA22506.1 481 GPNGSGKSTLMRAINNEQVegfpkKSEVKTVFVEHDL 517
                 899**************99666544556888888776 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.27
      CLP1_P   1 GpkdsGKSTlarlLlNyal 19 
                 Gp+ +GKSTl+ +L  +++
  EEA22506.1 724 GPNGAGKSTLVNVLTGELI 742
                 899***********99876 PP

>> NB-ARC  NB-ARC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.0    0.0011      0.42      24      48 ..     478     500 ..     466     550 .. 0.86
   2 ?    1.9   0.0      0.27     1e+02      23      38 ..     720     735 ..     708     751 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.0011
                 EEEESTTSSHHHHHHHHCCSHCCCC CS
      NB-ARC  24 alvGmgGvGKttlakqilnksdeve 48 
                 +l G  G+GK+tl++ i+n+  +ve
  EEA22506.1 478 GLLGPNGSGKSTLMRAINNE--QVE 500
                 689****************9..555 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.27
                 EEEEESTTSSHHHHHH CS
      NB-ARC  23 valvGmgGvGKttlak 38 
                 +a+ G  G GK+tl++
  EEA22506.1 720 IAVIGPNGAGKSTLVN 735
                 799***********86 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0     0.052        19       8      30 ..      71      94 ..      65      95 .. 0.81
   2 ?    6.0   0.0     0.045        17       1      28 [.     188     215 ..     188     217 .. 0.92

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.052
                HH.T-SSHHHHHHHHHHHHHHHHC CS
        HEAT  8 ll.sDpspeVReaAakaLgalaev 30
                 l + ++++ Re A++a+ a+ae+
  EEA22506.1 71 QLsNKKDANARERAVEAIRAIAEH 94
                5535589999************98 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.045
                 HHHHHHHHHT-SSHHHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgala 28 
                 l+P++ + + D+ peV +aA  ++ +++
  EEA22506.1 188 LIPVVSESMWDTKPEVKKAAYGTMEKIC 215
                 79******************99988887 PP

>> MukB  MukB N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   0.0    0.0063       2.4      77     141 ..     468     533 ..     465     562 .. 0.79
   2 ?    4.5   0.0     0.069        26      31      53 ..     722     744 ..     712     754 .. 0.87

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0063
                 GGGB-SSEEEEEEEEE-TTS-EEEEEEEEEE-SSTTT-EEEEE.EEEES--TT--HHHHHEE--SS CS
        MukB  77 yGklkaGvcysvlevvnsreqrllvgvrleqvagrdkkvdikp.falqgleedvkltdvllekldd 141
                 + +lk+G+ y +l    s +  l+ +++ eqv g  kk ++k+ f+ ++l+   + + v+  ++++
  EEA22506.1 468 HLRLKRGQRYGLLGPNGSGKSTLMRAINNEQVEGFPKKSEVKTvFVEHDLDAADTEQTVIGWTQKK 533
                 5689**********************************9998735567888887777777655554 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.069
                 HHS--SHHHHHHHHHHHHHHS-- CS
        MukB  31 lsGgnGaGksttmaafvtaliPd 53 
                 + G nGaGkst +  +   liP 
  EEA22506.1 722 VIGPNGAGKSTLVNVLTGELIPT 744
                 6799*********9999999996 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.0     0.011         4      30      89 ..     471     533 ..     463     545 .. 0.72
   2 ?    4.6   0.0     0.054        20      32      57 ..     716     741 ..     710     774 .. 0.81

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.011
       AAA_7  30 lknkkpvllvGptGtGKtviikdllkkld...kekylsltinfsaqtsanqlqdiiesklekr 89 
                 lk+++   l Gp G+GK+++++ + ++     ++k  ++t+ + +  +a+++ +++    +k+
  EEA22506.1 471 LKRGQRYGLLGPNGSGKSTLMRAINNEQVegfPKKSEVKTVFVEHDLDAADTEQTVIGWTQKK 533
                 677888889***********9995554331445777777777777777777777666655555 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.054
       AAA_7  32 nkkpvllvGptGtGKtviikdllkkl 57 
                  +  + ++Gp G GK+++++ l+ +l
  EEA22506.1 716 LGSRIAVIGPNGAGKSTLVNVLTGEL 741
                 5677899************9877665 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0     0.032        12      46      73 ..     473     500 ..     463     528 .. 0.84
   2 ?    5.4   0.0     0.037        14      48      73 ..     718     743 ..     693     774 .. 0.84

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.032
   IstB_IS21  46 kkenivllGpsGvGKshlaialgveavr 73 
                 + +   llGp G GKs l  a+  e v+
  EEA22506.1 473 RGQRYGLLGPNGSGKSTLMRAINNEQVE 500
                 5666779***************999886 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.037
   IstB_IS21  48 enivllGpsGvGKshlaialgveavr 73 
                   i+++Gp G+GKs l   l  e + 
  EEA22506.1 718 SRIAVIGPNGAGKSTLVNVLTGELIP 743
                 5699************9988877765 PP

>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.0      0.19        72      49      72 ..     478     501 ..     460     531 .. 0.76
   2 ?    8.0   0.0    0.0065       2.4      50      82 ..     722     754 ..     707     785 .. 0.79

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.19
       Rad17  49 LisGPsGCgkstvvkvLskelgik 72 
                  + GP G gkst ++ +  e +  
  EEA22506.1 478 GLLGPNGSGKSTLMRAINNEQVEG 501
                 467************999888765 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0065
       Rad17  50 isGPsGCgkstvvkvLskelgiklrewlnpvsl 82 
                 + GP G gkst v+vL+ el +   +     ++
  EEA22506.1 722 VIGPNGAGKSTLVNVLTGELIPTAGDVYQHENI 754
                 67***************9998876665555555 PP

>> Adaptin_N  Adaptin N terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   0.0    0.0033       1.2     341     481 ..      65     214 ..      62     232 .. 0.77
   2 ?    0.8   0.1      0.36   1.4e+02      99     162 ..     249     312 ..     229     324 .. 0.76

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0033
                 HHHHHHHTTSSXXHHHHHHHHHHHHHHHHHS...CCHHHHHHHHHHHHHTTXXHHH....HHHHHHHHHHHHHHSTTTSTTCHHHHCCTCCGXXSHHHH CS
   Adaptin_N 341 vkeLkkyvkevadedfksklvkaIgrlaekf...atdaewvldvllellslsgesv....kdeivevirdliqkvpelheeiiekLaellekieseear 432
                 v+ Lkk++++++d   ++++v+aI+ +ae +   + ++ + ++ l   l   g+++    +++ v++i  +   +p+  + ++  +++ + + +    +
  EEA22506.1  65 VESLKKQLSNKKDANARERAVEAIRAIAEHSsvaPGVEPHLVTLLGPTLNAVGDKMtnvkNAAQVAAIALVKAINPNATKAALPSIINSILSAQKWPEK 163
                 7889****99*9*****************9999888888888888888888775555655555566666666668888888999999998886666666 PP

                 HHHHHHHHHTTTTXTT.....HHHHHHCTTTTTTTSXHHHHHHHHHHHHHH CS
   Adaptin_N 433 aaaiWllGeygelvsn.te.sasdllrslaekfvlesekvklqiltalvKl 481
                    + ++   +e ++      ++dl+  + e++ +++ +vk ++  ++ K 
  EEA22506.1 164 MTGLQCIEALVETAPAqLAfLVPDLIPVVSESMWDTKPEVKKAAYGTMEKI 214
                 666777777777777644467888888888888888888888888888876 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.36
                 HHHHHCCC--CCCHHHHHHHHHHHHT-SSHHHHHHHHHHHHHCCCCCHHCCCCC.HHHHHHHCTT CS
   Adaptin_N  99 ALrvLssirvpelaedlapaikkllkdrspyvrkkAalailklykkdpdllrkq.lveeikells 162
                 A ++++++ +p+la +++p +++ l  r++ +++k+a+++  + k+ +d +    +++++  +l+
  EEA22506.1 249 ATTFVTDVHEPTLA-IMVPLLERGLAERETAIKRKSAVIVDNMCKLVEDPQIVAsFLPKLMPALN 312
                 66777888888776.999********************999999995554433445777776665 PP

>> Cytidylate_kin  Cytidylate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.0     0.068        25       5      20 ..     481     496 ..     478     502 .. 0.88
   2 ?    6.0   0.0     0.023       8.6       1      22 [.     720     741 ..     720     806 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.068
                     -STTSSHHHHHHHHHH CS
  Cytidylate_kin   5 GPagsGKssvaralae 20 
                     GP gsGKs++ ra+ +
      EEA22506.1 481 GPNGSGKSTLMRAINN 496
                     9***********9876 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.023
                     EEEE-STTSSHHHHHHHHHHHH CS
  Cytidylate_kin   1 iaiDGPagsGKssvaralaekl 22 
                     ia+ GP g+GKs++   l+ +l
      EEA22506.1 720 IAVIGPNGAGKSTLVNVLTGEL 741
                     8999**********99998776 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0      0.27     1e+02      31      52 ..     472     493 ..     467     546 .. 0.73
   2 ?    7.0   0.0      0.01       3.8      29      53 ..     714     737 ..     691     815 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.27
      AAA_25  31 pagelallaGapgtGKttlald 52 
                  +g    l G+ g+GK+tl   
  EEA22506.1 472 KRGQRYGLLGPNGSGKSTLMRA 493
                 566777799*********9755 PP

  == domain 2  score: 7.0 bits;  conditional E-value: 0.01
      AAA_25  29 llpagelallaGapgtGKttlaldl 53 
                 +  +g+ ++++G+ g+GK+tl+  l
  EEA22506.1 714 V-SLGSRIAVIGPNGAGKSTLVNVL 737
                 4.6899**************98665 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   0.0     0.007       2.6      25      44 ..     479     498 ..     467     565 .. 0.77
   2 ?    3.4   0.0      0.16        61      24      44 ..     721     741 ..     712     820 .. 0.67

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.007
    ATPase_2  25 iYGpegsGKtaLlkeiienl 44 
                 + Gp gsGK++L++ i +++
  EEA22506.1 479 LLGPNGSGKSTLMRAINNEQ 498
                 57************987765 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.16
    ATPase_2  24 fiYGpegsGKtaLlkeiienl 44 
                  + Gp g GK++L++ +  +l
  EEA22506.1 721 AVIGPNGAGKSTLVNVLTGEL 741
                 577***********9887666 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0     0.051        19       4      20 ..     479     495 ..     478     526 .. 0.84
   2 ?    3.5   0.0      0.17        64       4      20 ..     722     738 ..     719     761 .. 0.85

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.051
                 EE--SSSSHHHHHHHGG CS
       AAA_5   4 LvGppGtgKselaerla 20 
                 L+Gp G+gKs+l++ + 
  EEA22506.1 479 LLGPNGSGKSTLMRAIN 495
                 89**********99875 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.17
                 EE--SSSSHHHHHHHGG CS
       AAA_5   4 LvGppGtgKselaerla 20 
                 ++Gp G gKs+l+  l 
  EEA22506.1 722 VIGPNGAGKSTLVNVLT 738
                 79**********99876 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0      0.26        98      27      43 ..     479     495 ..     474     511 .. 0.90
   2 ?    6.5   0.0     0.013         5      25      65 ..     720     761 ..     709     776 .. 0.75

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.26
  Mg_chelatase  27 lvGppGsGKtmlakrlp 43 
                   l+Gp GsGK+ l ++++
    EEA22506.1 479 LLGPNGSGKSTLMRAIN 495
                   78**********99876 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.013
  Mg_chelatase  25 lllvGppGsGKtmlakrlps.llpplseeealevakiasvag 65 
                   + ++Gp G+GK+ l + l++ l+p   +  ++e  +ia +++
    EEA22506.1 720 IAVIGPNGAGKSTLVNVLTGeLIPTAGDVYQHENIRIAYIKQ 761
                   7789*************9963677766666666666655554 PP

>> Ploopntkinase3  P-loop Nucleotide Kinase3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0     0.031        12       8      53 ..     479     527 ..     475     535 .. 0.62
   2 ?    4.4   0.0     0.086        32       6      26 ..     720     740 ..     717     761 .. 0.86

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.031
  Ploopntkinase3   8 lvGqPGaGkstlmaeltkgfdrskveqee...etvphdvlvdrttGevv 53 
                     l+G  G+Gkstlm ++ +  +    +++e     v hd  +  t+  v+
      EEA22506.1 479 LLGPNGSGKSTLMRAINNEQVEGFPKKSEvktVFVEHDLDAADTEQTVI 527
                     78999********998765443222222221145556555555555555 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.086
  Ploopntkinase3   6 iylvGqPGaGkstlmaeltkg 26 
                     i ++G  GaGkstl+  lt  
      EEA22506.1 720 IAVIGPNGAGKSTLVNVLTGE 740
                     6789************99965 PP

>> AAA_13  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   0.0    0.0045       1.7      23      49 ..     481     507 ..     469     539 .. 0.78
   2 ?    4.6   0.0     0.027        10      22      55 ..     723     756 ..     714     849 .. 0.65
   3 ?   -3.1   0.6       5.8   2.1e+03     529     580 ..     940     985 ..     936    1046 .. 0.65
   4 ?   -3.2   0.9       6.3   2.3e+03     414     445 ..    1018    1049 ..    1009    1058 .. 0.56

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0045
      AAA_13  23 GwNGaGKTtLSrllrslelgetepkfa 49 
                 G NG+GK+tL r++++ + +   +k +
  EEA22506.1 481 GPNGSGKSTLMRAINNEQVEGFPKKSE 507
                 99*************977666555543 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.027
      AAA_13  22 YGwNGaGKTtLSrllrslelgetepkfangsiei 55 
                  G NGaGK+tL ++l       + + +++++i+i
  EEA22506.1 723 IGPNGAGKSTLVNVLTGELIPTAGDVYQHENIRI 756
                 49***********998744444445555555544 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 5.8
      AAA_13 529 ivviDDPvSSLDsnslfivfsliksrllkkkkakQlfiLTHnleffkevkkn 580
                  +v+D P   LD +sl   +  ik+          + i TH+ ef  +++++
  EEA22506.1 940 LIVLDEPTNYLDRDSLGALSKAIKTFE------GGVVIITHSREFTENLTEE 985
                 577777777777777777777777765......6678888888887777664 PP

  == domain 4  score: -3.2 bits;  conditional E-value: 6.3
      AAA_13  414 ykkkykklekaieklekelkeeeaelkkleee 445 
                   ++++++l +++ek+ek++k +++el+k++++
  EEA22506.1 1018 EEDTFDALGNKVEKVEKKAKLSASELRKKRKD 1049
                  34555566666666666666666666555543 PP

>> ATP-synt_ab  ATP synthase alpha/beta family, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.0     0.028        11      12      38 ..     472     498 ..     467     542 .. 0.90
   2 ?    3.8   0.0      0.11        40       6      35 ..     709     738 ..     706     822 .. 0.83

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.028
                  BTT-EEEEEESTTSSHHHHHHHHHHHS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab  12 vqGqrtlipgafgvGktvisqslskqs 38 
                   +Gqr +++g +g Gk+++++++ +++
   EEA22506.1 472 KRGQRYGLLGPNGSGKSTLMRAINNEQ 498
                  69*******************998874 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.11
                  HHHS-EBTT-EEEEEESTTSSHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab   6 DalfpivqGqrtlipgafgvGktvisqsls 35 
                  D  f +  G r++++g +g Gk+++++ l+
   EEA22506.1 709 DITFQVSLGSRIAVIGPNGAGKSTLVNVLT 738
                  77888999****************998775 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.0     0.029        11      58      77 ..     479     498 ..     460     516 .. 0.83
   2 ?    3.9   0.0     0.069        26      56      94 ..     720     766 ..     711     781 .. 0.67

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.029
      DUF815  58 LwGarGtGKSslvkallney 77 
                 L G  G+GKS+l++a+ ne 
  EEA22506.1 479 LLGPNGSGKSTLMRAINNEQ 498
                 89**************9986 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.069
      DUF815  56 vLLwGarGtGKSslvkallneyaeeg........Lrlievekedlke 94 
                 + ++G  G+GKS+lv  l+ e+  +         +r+  ++++  ++
  EEA22506.1 720 IAVIGPNGAGKSTLVNVLTGELIPTAgdvyqhenIRIAYIKQHAFAH 766
                 56789***********9998865544344443346666666555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1065 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1054  (0.0587874); expected 358.6 (0.02)
Passed bias filter:                      717  (0.0399911); expected 358.6 (0.02)
Passed Vit filter:                       111  (0.00619109); expected 17.9 (0.001)
Passed Fwd filter:                        48  (0.00267723); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              48  [number of targets reported over threshold]
# CPU time: 1.05u 0.35s 00:00:01.40 Elapsed: 00:00:00.48
# Mc/sec: 6657.75
//
Query:       EEA22507.1  [L=500]
Description: sugar transporter family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-42  146.2  21.0    3.2e-41  141.7  21.0    2.0  1  Sugar_tr  Sugar (and other) transporter
    5.2e-31  107.9  47.2    4.8e-27   94.8  31.4    2.2  2  MFS_1     Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.052   12.0   0.2      0.052   12.0   0.2    2.1  2  TRI12     Fungal trichothecene efflux pump (TRI12)


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  141.7  21.0   5.3e-45   3.2e-41      17     446 ..      64     471 ..      57     476 .. 0.85

  Alignments for each domain:
  == domain 1  score: 141.7 bits;  conditional E-value: 5.3e-45
                 HCGGGTHHHHHHHHTSTT--SHHHHHH.......HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHH CS
    Sugar_tr  17 gvigafltllkfaknfglsksksskee....ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvl 111
                 +++++  +  +++ +f +s s +s ++     ++ +++   ++l  + +G++++g+l+dr+GRk+ +++ +vlf+i  + +++++   ++ +++++R l
  EEA22507.1  64 FLVAFCGWTWDAFDFFSVSISLTSLAKyfdrPNSEITWGITLVLMLRSVGAIIFGILSDRYGRKWPFVANNVLFIILELGTGFCQ---TYNQFLACRAL 159
                 5666666777777788888888888778888777778888888889***************************************...9********** PP

                 HHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHHTT-HHHHHHH CS
    Sugar_tr 112 vGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPrylvekgkeeeakev 210
                  Gi++G+ ++ +  ++ E +p++ Rg++ ++ q +++fG l+ + f  gl +t+   gwr l+++ + p++l++i++l lPE+  y      +e+ + +
  EEA22507.1 160 FGIAMGGLYGNIAATALEDCPPEARGIISGMLQQGYAFGYLLVTAFARGLVDTTP-HGWRPLFWFGACPPVLFIIFRLCLPETQAYQ----SRERVRNS 253
                 **************************************************88888.8**************************5553....33344555 PP

                 HHHHHHCHHHHHHH.HHHHHHHHHHHH.....HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THHHHHHHHHHHHHHHHHHHHH CS
    Sugar_tr 211 laklrgeedadrel.aeekdsleaeqeeekaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsksllvtiivgvvnfvatfvai 308
                 la      ++   +  e k +           +k+ ++       l+++v+l+++ ++  + ++ +y++++  + g+s   +vt+  +v n  a   + 
  EEA22507.1 254 LAG-----GVAGTFlSEGKVA-----------VKNHWKL------LIYIVLLMAGFNFLSHGSQDIYPTMLSAQFGFSAN-AVTVTQVVANLGAMTGGT 329
                 555.....3333330233333...........4444666......8999999999*************************.888888888887766663 PP

                 ...HHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHH CS
    Sugar_tr 309 ...flvdrfGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisl 404
                    + +  fGRR   ++ a+++ +++     + +++++k    s++a +f+  f +  a  wg +p +++ El+p  +R++a   a+++ +l++ + s+
  EEA22507.1 330 lcgWASQIFGRRFSIIVIAIVGGALLY----PYDFITDK----SVIAAAFFEQFCVQGA--WGVIP-IHLMELAPGPIRTFAVGTAYQLGNLVSSASST 417
                 3559********555555555554444....45899999....6777777777766665..88888.889***************************** PP

                 HHHHHHCHHH............T-HHHHHHHHHHHHHHHHHHHHS--STT--CC CS
    Sugar_tr 405 lfpiiteaig............ggyvflvfaglavlfiifvfffvpetkgrtle 446
                 +  +i e+               g+v  +f+g++++++i+v ff pe  gr+++
  EEA22507.1 418 IESTIGERFPlpptktgakrydYGKVICIFMGCVYAYVIIVTFFGPENLGREFD 471
                 *********************999***************************996 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.8  31.4     8e-31   4.8e-27      13     350 ..      74     413 ..      61     416 .. 0.81
   2 !   27.1   7.8     3e-10   1.8e-06      19     172 ..     298     461 ..     296     497 .. 0.77

  Alignments for each domain:
  == domain 1  score: 94.8 bits;  conditional E-value: 8e-31
       MFS_1  13 si...lgpalpl.alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgagalfpaga 107
                 ++   ++++++l  la+ +    sei + +tl+  + +v+++++G lsdr+Gr++ +++  +lf++  l   f++++  +l++r+l G+++g+l+ ++a
  EEA22507.1  74 DAfdfFSVSISLtSLAKYFDRPNSEITWGITLVLMLRSVGAIIFGILSDRYGRKWPFVANNVLFIILELGTGFCQTYNQFLACRALFGIAMGGLYGNIA 172
                 33444555566669*****************************************************77777988888********************* PP

       MFS_1 108 aliadwfpkeergraigllsagfslGailgpllgglla..sslgWravfyilaivsllafvlfllllpeepperkrkspkeee.kgtgpaplvpawkal 203
                 a + +  p+e rg   g+l+ g+++G++l  +++  l+  +  gWr +f++ a   +l+++ f l lpe++   +r++ +  +  g++++ l++  k  
  EEA22507.1 173 ATALEDCPPEARGIISGMLQQGYAFGYLLVTAFARGLVdtTPHGWRPLFWFGACPPVLFII-FRLCLPETQAYQSRERVRNSLaGGVAGTFLSE-GKVA 269
                 ***************************99999999999444556**************866.89999999999999999888855555555555.8888 PP

       MFS_1 204 lkdpvlw.illialllfffgfsg....lltllplylqevlgls..glllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglalla 295
                 +k+   w +l++++ll++ gf++         p++l  ++g+s  + ++++    ++ l+++ ++ l+g+ s+ +gr   ++ ++++++++ ++l++  
  EEA22507.1 270 VKNH--WkLLIYIVLLMA-GFNFlshgSQDIYPTMLSAQFGFSanA-VTVT--QVVANLGAMTGGTLCGWASQIFGR---RFSIIVIAIVGGALLYPYD 359
                 8888..863444444443.44444688888999999*******742.3333..44444444444889******9885...8889999999999999999 PP

       MFS_1 296 vtssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfntagslgga 350
                 +++++++++ + ++  f++  +++ +   +++lap   + +a+g +  +g+l+++
  EEA22507.1 360 FITDKSVIA-AAFFEQFCVQGAWGVIPIHLMELAPGPIRTFAVGTAYQLGNLVSS 413
                 995665555.788889999999*************99999999998888877765 PP

  == domain 2  score: 27.1 bits;  conditional E-value: 3e-10
       MFS_1  19 lplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrr.vlllglllfalglllll.fasslwlllvlrvlqGlgagalfpagaaliadwfp 115
                 +p +l+ ++g+s+ ++    ++  lga+ +  + G+ s+ fGrr  ++++++++ al   ++  f ++   ++++ ++  ++  +++ ++ + + +++p
  EEA22507.1 298 YPTMLSAQFGFSANAVTVTQVVANLGAMTGGTLCGWASQIFGRRFsIIVIAIVGGALL--YPYdF-ITDKSVIAAAFFEQFCVQGAWGVIPIHLMELAP 393
                 566899***************************************6666666666666..99999.77788**************************** PP

       MFS_1 116 keergraigllsagfslGailgpllggllasslg.............Wravfyilaivsllafvlfllll 172
                 ++ r++a+g ++   +l +     + + + + +                ++ ++++ v++ ++++   ++
  EEA22507.1 394 GPIRTFAVGTAYQLGNLVSSASSTIESTIGERFPlpptktgakrydyGKVICIFMGCVYAYVIIV--TFF 461
                 ********877777777666666666666666667777777777665555555555555555553..444 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.2   8.7e-06     0.052      85     147 ..     104     166 ..      78     173 .. 0.85
   2 ?   -3.0   2.9       0.3   1.8e+03      74     158 ..     306     391 ..     278     469 .. 0.49

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 8.7e-06
       TRI12  85 tlwttgqavsilvmgrltdrfgrrpfvilthilglvgaivgctatkfntllaamtllgvaagp 147
                 tl  + ++v  +++g l+dr+gr+   ++  +l ++  +    ++ +n +la+ +l+g+a g 
  EEA22507.1 104 TLVLMLRSVGAIIFGILSDRYGRKWPFVANNVLFIILELGTGFCQTYNQFLACRALFGIAMGG 166
                 788889999**************95556777888888887778899**************985 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.3
       TRI12  74 vgqsensslfs.tlwttgqavsilvmgrltdrfgrrpfvilthilglvgaivg..ctatkfntllaamtllgvaagpagasplfvgel 158
                  g s n   ++  +  +g      + g  ++ fgrr  +i+  i+g  ga++      t    + aa+       g  g  p+ + el
  EEA22507.1 306 FGFSANAVTVTqVVANLGAMTGGTLCGWASQIFGRRFSIIVIAIVG--GALLYpyDFITDKSVIAAAFFEQFCVQGAWGVIPIHLMEL 391
                 4555554433303334455555566677777888888888777777..3333200222333333334433444455555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (500 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       571  (0.0318478); expected 358.6 (0.02)
Passed bias filter:                      352  (0.019633); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3383.36
//
Query:       EEA22508.1  [L=296]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (296 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       451  (0.0251548); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.24s 00:00:00.70 Elapsed: 00:00:00.41
# Mc/sec: 2164.25
//
Query:       EEA22509.1  [L=567]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.6e-43  147.0  34.9    6.6e-43  147.0  34.9    1.8  2  MFS_1     Major Facilitator Superfamily
    1.8e-12   46.8  10.4    1.8e-12   46.8  10.4    2.2  2  Sugar_tr  Sugar (and other) transporter
  ------ inclusion threshold ------
       0.22    9.8  17.0        0.4    8.9   7.8    3.2  3  OATP      Organic Anion Transporter Polypeptide (OATP) family


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  147.0  34.9   1.1e-46   6.6e-43       4     353 .]     137     518 ..     134     518 .. 0.84
   2 !   10.2  13.4   4.3e-05      0.26      71     172 ..     452     552 ..     447     563 .. 0.87

  Alignments for each domain:
  == domain 1  score: 147.0 bits;  conditional E-value: 1.1e-46
       MFS_1   4 aaflsalarsilgpalplalaedlgispseigl.lltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlgaga 101
                 + +l+ +a+s+ +pa+   + ++++++  ++ +  +++++lg +++ l++++ls+ +Gr  ++ l+ ++f+++++ ++ a+sl  l+ +r+++G++++a
  EEA22509.1 137 LRLLIPFASSMMAPAIL-NIHDEFHSNSITLDTlSISIFMLGVGAGPLLFAPLSELYGRNLIYHLSNFFFSISSVGCARAPSLKSLIGFRLIAGIAGSA 234
                 567999**********9.9******7777766646788***********************************77777436655*************** PP

       MFS_1 102 lfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee............ 188
                 ++++g+  iad++pke rg+ + l+ +g  +G+++gp +gg++++ +gWr++f++l+ivs  +  l++++l+e++p+   k ++ ++            
  EEA22509.1 235 VISNGGGTIADIVPKESRGLITTLMVLGQLIGPVIGPTVGGYVSQGVGWRWIFWLLTIVSGAFTCLGFIFLRETHPPTLLKWKAARLrketgnkllyhk 333
                 ***************************************************************999999999999999999888888999999886655 PP

       MFS_1 189 ...kgtgpaplvp...........awkallkdpvlw.illialllfffgfsglltllplylqevlgls....glllaglllallalvgailallagrls 268
                    +       vp           ++++l+++pv++ + ++++l+ + ++ +++++ +++ q+++g++    gll+ g  +++++lv+    ++ +r+s
  EEA22509.1 334 gksS-------VPqkqlfmeacqrPLRMLFTNPVIFmVSIYIALVLGYAYILFTSFAFVF-QQQYGFGegttGLLYFG--IGIGMLVA---LVWMSRYS 419
                 5542.......2244455567888***********8655555555555777788888887.*******7665555555..66666665...99****** PP

       MFS_1 269 dr........lgr...rrrlllallllllaalglallavtssavllllvlvl....iGfglgfv.fpsllalasdlappeeagtasglfntagslggal 351
                 dr        +gr   ++rl+  l +++++ +g+++ +++   +++++v ++    +G+g  ++ +++ ++l++ ++   +a++a+++++ +++l++al
  EEA22509.1 420 DRifaqkerqMGRskaEFRLIPLLYGTFFIPVGFIIYGWAIQFHVYWVVPIFgtmlMGVGTVLAlVVTQTYLIDAFT--VHAASANAANSPIRCLAAAL 516
                 **99999999555666************************9999999977776655777666664555555555555..9999**************99 PP

       MFS_1 352 gp 353
                  p
  EEA22509.1 517 LP 518
                 76 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 4.3e-05
       MFS_1  71 lfalglllllfasslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlf 168
                 +f++ ++++ f + +w + +++ +l+G+g+ +++ + ++++ d f+  + ++a++  s    l+a+l pl g  l+++l + +   +la+++l++ vl 
  EEA22509.1 452 GFIIYGWAIQF-HVYWvVPIFGTMLMGVGTVLALVVTQTYLIDAFTV-HAASANAANSPIRCLAAALLPLSGTSLYDALTFGWGNTMLALIALIFSVLP 548
                 44444455557.99**99****************************9.**********************************************99985 PP

       MFS_1 169 llll 172
                 ++ +
  EEA22509.1 549 WITY 552
                 5444 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.8  10.4   3.1e-16   1.8e-12      44     213 ..     163     332 ..     140     422 .. 0.71
   2 ?   -0.8   2.0     0.089   5.3e+02      79     127 ..     442     491 ..     430     502 .. 0.78

  Alignments for each domain:
  == domain 1  score: 46.8 bits;  conditional E-value: 3.1e-16
                 ...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHH CS
    Sugar_tr  44 ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvsl 142
                 s +l +l+ sif++G  +G l++ +l++ +GR  ++  ++++f+i++v +a a+   s+  li  R+++Gi+  ++      +i+ i pk+ Rg +++l
  EEA22509.1 163 SITLDTLSISIFMLGVGAGPLLFAPLSELYGRNLIYHLSNFFFSISSVGCARAP---SLKSLIGFRLIAGIAGSAVISNGGGTIADIVPKESRGLITTL 258
                 45567899**********************************************...9**************999999999***************998 PP

                 HHHHHHHHHHHHHHHHHHH.HTSS-TTHHHHHHHC.CHHHHHHHHHHGGGS---..H...HHHHHTT-HHHHHHHHHH CS
    Sugar_tr 143 yqlaitfGilvaaifglgl.nktsnadgwrillgl.qlvpallllilllflPES..P...rylvekgkeeeakevlak 213
                   l    G+l++ ++g  +  ++s+ +gwr+ ++l ++v+  + +++++fl+E+  P    +   + ++e   + l+ 
  EEA22509.1 259 MVL----GQLIGPVIGPTVgGYVSQGVGWRWIFWLlTIVSGAFTCLGFIFLREThpPtllKWKAARLRKETGNKLLYH 332
                 655....666666666555555555666****9972667777889999*****9332222344444444444444444 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.089
                 HHHHHHHHHHHHHHHH-TTTTSS-TGG.GGGHHHHHHHHHHHHHHHHHHH CS
    Sugar_tr  79 lliaavlfvigavlqaaakgknsvevl.ivgRvlvGigvGlasvlvPmyi 127
                 ll ++++  +g ++ ++a +   ++v+ i+g +l+G+g  la v++ +y+
  EEA22509.1 442 LLYGTFFIPVGFIIYGWAIQFHVYWVVpIFGTMLMGVGTVLALVVTQTYL 491
                 67788888899999999995555554447889999999988888888776 PP

>> OATP  Organic Anion Transporter Polypeptide (OATP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   7.8   6.8e-05       0.4     139     348 ..     225     408 ..     211     421 .. 0.62
   2 ?    5.2   0.6   0.00087       5.2     130     162 ..     464     496 ..     459     509 .. 0.83
   3 ?   -2.2   0.0      0.15   9.1e+02      59      95 ..     520     554 ..     505     563 .. 0.74

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 6.8e-05
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxx RF
        OATP 139 qlllGiGatpiytlGisYidDnvkkknsplylgilyalrilGpalGfllGslllklyvdidseisltpkdprWvgaWWlgflilgvllllaaipl.ffF 236
                  l++Gi+++++++ G   i D v k++  l   ++   +++Gp++G ++G+++ +                 W   +Wl  +++g++++l  i+l    
  EEA22509.1 225 RLIAGIAGSAVISNGGGTIADIVPKESRGLITTLMVLGQLIGPVIGPTVGGYVSQ--------------GVGWRWIFWLLTIVSGAFTCLGFIFLrETH 309
                 5899***********************************************6655..............335666689988888888777554431345 PP

                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxx RF
        OATP 237 PkelpkkkeerakkkseeesaekkeekkkkeksksseeeelkslkdfpkalkrllknpifllvilssvfeillvaGfitFlpk....ylEtqFslsase 331
                 P +l k k+ r +   +e+ + k   +k k++      ++   ++   + l++l++np+ ++v++     i lv G++  l        ++q++  + +
  EEA22509.1 310 PPTLLKWKAARLR---KETGN-KLLYHKGKSSVP----QKQLFMEACQRPLRMLFTNPVIFMVSIY----IALVLGYAYILFTsfafVFQQQYGFGEGT 396
                 5554422222222...22111.112222222222....2346788888999*******98777665....33333333322220000235555544443 PP

                 xxxxxxxxxxxxxxxxx RF
        OATP 332 AnlltGvvvipgaalGi 348
                   ll      +g+++G+
  EEA22509.1 397 TGLL-----YFGIGIGM 408
                 3332.....33444444 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.00087
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP 130 klvllfflaqlllGiGatpiytlGisYidDnvk 162
                  ++++ +++ +l+G+G+++   + ++Y+ D  +
  EEA22509.1 464 VYWVVPIFGTMLMGVGTVLALVVTQTYLIDAFT 496
                 4677999********************988665 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 0.15
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        OATP  59 fggrghrPrwigigallmalgslllalPhfisgkyey 95 
                  g++   +   g+g  ++al +l++++  +i+  y+y
  EEA22509.1 520 SGTSLYDALTFGWGNTMLALIALIFSVLPWIT--YRY 554
                 56666667788999999999999998777777..444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (567 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       657  (0.0366445); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.66u 0.32s 00:00:00.98 Elapsed: 00:00:00.46
# Mc/sec: 3672.08
//
Query:       EEA22510.1  [L=1619]
Description: 3-oxoacyl-[acyl-carrier-protein] synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-66  223.6   0.0    3.2e-66  222.6   0.0    1.5  1  Fas_alpha_ACP    Fatty acid synthase subunit alpha Acyl carri
    2.3e-28   99.3   0.1    6.8e-28   97.7   0.1    1.9  1  FAS_I_H          Fatty acid synthase type I helical domain
    1.6e-22   80.3   0.3      4e-22   79.0   0.3    1.7  1  ketoacyl-synt    Beta-ketoacyl synthase, N-terminal domain
    5.4e-16   58.7   0.0    1.7e-15   57.1   0.0    1.9  2  Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
     0.0027   17.5   0.0     0.0062   16.3   0.0    1.6  1  betaPIX_CC       betaPIX coiled coil
     0.0078   16.1   0.0      0.016   15.2   0.0    1.5  1  KR               KR domain
     0.0091   15.6   0.0      0.019   14.5   0.0    1.5  1  adh_short_C2     Enoyl-(Acyl carrier protein) reductase


Domain annotation for each model (and alignments):
>> Fas_alpha_ACP  Fatty acid synthase subunit alpha Acyl carrier domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  222.6   0.0   1.3e-69   3.2e-66       1     162 []     153     314 ..     153     314 .. 0.99

  Alignments for each domain:
  == domain 1  score: 222.6 bits;  conditional E-value: 1.3e-69
  Fas_alpha_ACP   1 eDepvkavdivraivaqklkkkldevplsksikdlvgGkStlqNEilgdLqaEfgslpekaedlpleelaealqesfsGklGkqssslisrlvssk 96 
                    +D p++a+div+++vaqkl+k++d++p++ksi++l+gGkStlqNEi+gdL++E+gslp+++ed+pl++l++al  +f+G++Gkq+sslis+l+ssk
     EEA22510.1 153 DDIPMTATDIVIVVVAQKLRKQFDQIPVTKSIQELSGGKSTLQNEIVGDLGTELGSLPDGSEDMPLTALGTALAGAFKGRPGKQVSSLISKLLSSK 248
                    699********************************************************************************************* PP

  Fas_alpha_ACP  97 mpggfnlaairkyLekrwglgpgrqdsvlllavtsePakRlgseaeAkafldsvvqkyakkagisL 162
                    mp++fn++air+yL++rwglgp+rqd+++ +++t ePa+Rl+s ++Ak+f+d+vvq+ya+ a++sL
     EEA22510.1 249 MPASFNQQAIRQYLSSRWGLGPQRQDTAISYSITLEPASRLTSVDAAKEFFDQVVQRYAAFANFSL 314
                    ************************************************************999876 PP

>> FAS_I_H  Fatty acid synthase type I helical domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.7   0.1   2.7e-31   6.8e-28       1     196 [.     338     517 ..     338     524 .. 0.82

  Alignments for each domain:
  == domain 1  score: 97.7 bits;  conditional E-value: 2.7e-31
     FAS_I_H   1 tkkqnelvrqqlevlaryLgvdseasereaaessaevaelqaeLdlweaEhgdeylkgikpiFdakKaRrydSaWNwarqdilklyydllqgrlkdvdr 99 
                 +k++++++ +++ev ++  +    ++e++ ++s++   +l++ L+ w++E+gd+  +g kpiFd  K R+yd++WNw r+ +++l  +l+ g+ +++d 
  EEA22510.1 338 QKEHQTALAEIYEVIGNLIKRR--EGEETTETSDDSDDSLREALSHWTSEFGDDMYSGTKPIFDTNKIRMYDAWWNWGRVALIALKQELQIGKPDSND- 433
                 5788888888888888887754..444455556677778999*******************************************9999999888855. PP

     FAS_I_H 100 eiksrlqrilnRadenlvdlvqyllkkakassgekyaaakelgekllknarsalsaapvyvelseptaPrttidekGnieYeEvpragvqeledyve 196
                   k r++ ilnR+++++ d++  +          ++ +++     l +  +s  ++ pv+v+++++ +P+t+i+e G++ YeEvpr +  +  + v 
  EEA22510.1 434 -SKDRIRMILNRWTSTCDDILSTFST--------NHGLLND----LRQPPASLQTRSPVFVYTKPAQGPHTKIHESGKMLYEEVPRRRLGQSRSFVD 517
                 .55899***************99944........2444444....44555688899******************************97666666555 PP

>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.0   0.3   1.6e-25     4e-22      69     251 ..    1087    1286 ..    1060    1288 .. 0.85

  Alignments for each domain:
  == domain 1  score: 79.0 bits;  conditional E-value: 1.6e-25
                     EGGTTSTHHHHHHHCTS-HHHHHHHHHHHHHHHHHTS.-HHTC....TTGGEEEEEEESSTHHHHHHHHHHHTT.GGGSCTTHHHHHSTTHHHH CS
  ketoacyl-synt   69 dfdpeffgispreaeamdpqqrllleaawealedagl.tpeel....dgsrvgvfiGvgagdyaalaaldedgs.evkaspkavgavlanviag 156 
                      ++++++gi+++   ++dp++ ++l+++ ea+ +ag+ +p e+    + s+ +++iG+gag + al++++++   e  a++++ + +  n++ +
     EEA22510.1 1087 GWNAATYGIPEDIISQVDPVTLYVLCCVSEAMYSAGIqDPYEIysqvHMSELANCIGTGAGGTMALRKMYRERYlEHAANSDIFQETFLNTMGA 1180
                     678999*******************************55666676545555**********8876666664444666666667777799***** PP

                     HHHHH.HT--SSEEEEESGGGHHHHHHHHHHHHHHTTS-SEEEEEEEE---SHHHHHHHHHTT.BB-TTSG..........GGTTBTTB-SB-B CS
  ketoacyl-synt  157 risya.lglrGpsvtvdtACsSslvavhaavqslrsgeadvalaGGvellltpeavagfsaag.llspdgr..........ckafdpkadGfvl 238 
                      +++  l  +Gp  t + AC+++   ++  ++s+  g++++al+GG++ ++ +ea + f++++  +++d+           c+++    +Gf+ 
     EEA22510.1 1181 WVNLLlLSSTGPIKTNSGACATAIESLDTGCESILLGKSKMALVGGTD-DFREEASYEFANMKaTVNTDEEvlqgrspsemCRPSTTTRNGFME 1273
                     ***9989*****************************************.999999999****967777755677789988899999999***** PP

                     B-EEEEEEEEECH CS
  ketoacyl-synt  239 GEGvGavvLkrle 251 
                     + G+G+ ++ ++e
     EEA22510.1 1274 AAGCGVQIITTAE 1286
                     ******9988776 PP

>> Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       3.5     9e+03       1      25 [.    1296    1320 ..    1296    1329 .. 0.82
   2 !   57.1   0.0   6.5e-19   1.7e-15      22     117 ..    1399    1496 ..    1381    1497 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 3.5
                       SEEEEEEEEEE--STSSSTSTTHHH CS
  Ketoacyl-synt_C    1 yavikgsavnsdgahnsltapngea 25  
                       ya+++++++ sd    s++ap +  
       EEA22510.1 1296 YAIVAHTQMASDRIGRSIPAPGQGV 1320
                       8999*******88999999998765 PP

  == domain 2  score: 57.1 bits;  conditional E-value: 6.5e-19
                       THHHHHHHHHHHHHHHT--GGGEEEEE-SS-SSHHHHHHHHHHHHHHHGGGGG..SCTSEEE-THHHH-B-GGGHHHHHHHHHHHHHHHTEE CS
  Ketoacyl-synt_C   22 ngeaqaraiekalaeagvdpedvdyveahgtgtplgDpiElealkkvfgekar..kqplavgSvKsniGHleaAaGvaelikvvlalkhgvi 111 
                       +++ q + i++ala  g++ +d+++ + hgt+t+++D++E++ +++ +++ +r   +pl   S+K ++GH ++AaG+  +   +++l++g++
       EEA22510.1 1399 QQNPQIAPIRAALAVWGLTVDDIGVASLHGTSTKANDKNEANVINQQMNKLGRkaGNPLLTVSQKWLTGHPKGAAGAWMFNGGMQVLQTGIV 1490
                       556677889*****************************************9999999*********************************** PP

                       --BTT- CS
  Ketoacyl-synt_C  112 pptlnl 117 
                       p + n 
       EEA22510.1 1491 PGNRNA 1496
                       **9986 PP

>> betaPIX_CC  betaPIX coiled coil
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   0.0   2.4e-06    0.0062       4      63 ..     487     546 ..     484     550 .. 0.90

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 2.4e-06
  betaPIX_CC   4 sapqlivpeeekiiveelksnqtvleekslVDtV.YaLkdevqelkqenkklkksleeEqk 63 
                 + p+  + e  k++ ee+ +   + +++s VD+V Y Lk   +el++   +lk+++ +E +
  EEA22510.1 487 QGPHTKIHESGKMLYEEVPR-RRLGQSRSFVDVVnYGLKGRTSELQKPVIQLKQQIGTEWR 546
                 7899999**********665.6789********99********************998865 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   6.1e-06     0.016       2     101 ..     573     678 ..     572     684 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 6.1e-06
                 EEEEET.TTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHH...HHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHS...S---EEEE------ CS
          KR   2 tylitG.GlGgLGlelarwlaekgarhlvllsRsaaadedsk...aliaelealgaevevvaaDvsdkdavealleeikaee...ppikGvihaAgvlr 93 
                 t l+tG G G+++  ++r l+e ga+  v +sR ++  ++ k   ++ ++  ++g + +v++   ++k++ eal++ i +++   + +  +i  A + +
  EEA22510.1 573 TILVTGaGPGSIACDIVRGLLEGGAEVFVTTSRAPP-ASTTKffnDMYKTHGSKGSKLTVLPFNQASKQDCEALVNYIYETKdgyRDLDAIIPFAAIGE 670
                 6799*9567*************************54.3333323256677777899******************99998877778999****9999999 PP

                 ---TTT-- CS
          KR  94 dklleemt 101
                 +++l+  +
  EEA22510.1 671 TGQLDGID 678
                 99888766 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.0   7.6e-06     0.019       1     152 [.     578     743 ..     578     801 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 7.6e-06
                   TTT.TSHHHHHHHHHHHTT-EEEEEESSGGH...HHHHHHHHHHTTSE.....EEE--TTSHHHHHHHHHHHHHHH...SSEEEEEE-----EGCSS CS
  adh_short_C2   1 Gaa.sgIGraiAkalaeeGaevvltdlneea...kkrveelaeelgae.....vlecDVtdeeqvealveevvekf...gklDilvnnagiapklkg 85 
                   Ga   +I+  i++ l e Gaev +t  +       k  +++ + +g++     vl+ + ++++++ealv+ + e+      lD ++  a+i ++ + 
    EEA22510.1 578 GAGpGSIACDIVRGLLEGGAEVFVTTSRAPPastTKFFNDMYKTHGSKgskltVLPFNQASKQDCEALVNYIYETKdgyRDLDAIIPFAAIGETGQL 674
                   566679*****************9998877622344555666666644434545***************987655333399*************888 PP

                   -GGGH-HHHHHHHHHHHTHHHHHHHHHHHH...HCTSCCEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHH CS
  adh_short_C2  86 pfletsreefdraldvnlyslfllakaalp...lmkeggsivnlssvgaervvpnynaygaaKaalealt 152
                   + ++++ e  +r + +nl  ++  +k+ ++   ++++    v l     + ++ +   y+ +K +le l 
    EEA22510.1 675 DGIDAKSELSHRLMLTNLLRILGHVKQQKQsrgYITR-PTAVMLPLSPNHGTFGGDGLYSESKLGLETLF 743
                   8889999999999999998888888877776653332.33444444445667777779999999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1619 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       699  (0.0389871); expected 358.6 (0.02)
Passed bias filter:                      566  (0.031569); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 1.12u 0.36s 00:00:01.48 Elapsed: 00:00:00.58
# Mc/sec: 8468.14
//
Query:       EEA22511.1  [L=463]
Description: citrate synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.2e-99  332.0   0.0    5.6e-99  331.6   0.0    1.1  1  Citrate_synt  Citrate synthase, C-terminal domain


Domain annotation for each model (and alignments):
>> Citrate_synt  Citrate synthase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  331.6   0.0  3.1e-103   5.6e-99       1     361 []      80     450 ..      80     450 .. 0.94

  Alignments for each domain:
  == domain 1  score: 331.6 bits;  conditional E-value: 3.1e-103
                   GGTTEEEEEESSEEEETTTTEEEETTEEHHHHHHHHS-HHHHHHHHHHSS---HHHHHHHHHHHHCTTS--HHHHHHHHCSSTTS-HHHHHHHHHHH CS
  Citrate_synt   1 glrgvaaleteisevdgekgelrYRGydieeLaeekssfeevaylLltgelPtkeelkefkeelaearklpekvlealealpkdahpmavlraavsa 97 
                   g++++a++e+++++vdg++g++ YRGyd+ + ++++++f ++a+l+++g +Pt+ee + f+++l +a+++++ v++++ a+p++a+   +l+a+++a
    EEA22511.1  80 GFTNTAVVESKVTYVDGKRGKIQYRGYDLADVVANNKKFIDTAHLMVFGFWPTAEEGAGFQQKLFDAMHIEQCVIDTIHAFPRTASTTLMLTAGLAA 176
                   789******************************99**************************************************9*********** PP

                   HHHHSTT........CTCHHH.......HHHHHHHHHHHHHHHHHHHHHHHHHHHTTS.--.---TTSSHHHHHHHHHHS.....S---HHHHHHHH CS
  Citrate_synt  98 lsaddee........seakee.......seeaalrdalkliAklptiaaaiyrarlgrepl.epddklsyaenflymlrg.....kkpdeeeaklld 173
                   ++a + +        +             +e+++r    l++ lp + a +y++++gr ++  p+++l+y+enflym+         p++++++ ++
    EEA22511.1 177 VQATQMDripahmakN----LylgnptlVDEQIVR----LMGVLPIVSAVAYCHHTGR-EFkSPRSDLTYIENFLYMCGHvqeetGLPNPRYVQNFE 264
                   9999999999855440....345544557888888....******************8.6768**99***********547888889********** PP

                   HHHHHHS--SSSHHHHHHHHHHTTT--HHHHHHHHHHHHTSTTTTTHHHHHHHHHHHHSSGG.GHHHHHHHHHHTTTS--TTBC-SSSSS--HHHHH CS
  Citrate_synt 174 lalvlhaDHelnaSTfaarvvaStladlysaiaagigalkGplhgganeavlkmleeigsaeveveeylekvlakekerlpGfGHrvykksDpRaki 270
                   +++ l+aDHe+++ST+a+ ++aS+l d++s+i++giga +Gplhgga e ++k +++igs + + +  +++v++ +kerl+G+GHrvyk++DpR ++
    EEA22511.1 265 RLWSLVADHEMTCSTAAVLLTASSLPDPISCIISGIGASYGPLHGGAIEFAYKDMADIGSVD-NCQTKIDRVKS-GKERLFGYGHRVYKVTDPRSEH 359
                   *************************************************************9.*********88.68******************** PP

                   HHHHHHHHHTCHTHHHHHHHHHHHHHHHHHHHHCHHGCT-EB-THHHHHHHHHHTT--GGGHHHHHHHHHHHHHHHHHHHHH.HT------E CS
  Citrate_synt 271 lkelaeelaeekgkdpllklaeeleevapevlkekeeknlypNvDfysgvlyralgipeelftvlfaisRvaGwlAhileql.adnkiiRPr 361
                   ++ ++e+l ee ++dpllk+a el ++a+e++++++ ++l+pN+D++++++y a+g+p++++ ++  isR+ G +Ah+ e +  +  i+RP+
    EEA22511.1 360 IQAVLETLKEEIDNDPLLKVAFELNRIAQEDEYFVS-RGLKPNADLFAAFTYGAMGFPPDFILTISTISRTQGLMAHWKEAMsGKPLIWRPT 450
                   ************************************.*******************************************77444459**95 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (463 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       436  (0.0243181); expected 358.6 (0.02)
Passed bias filter:                      403  (0.0224776); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.69u 0.35s 00:00:01.04 Elapsed: 00:00:00.56
# Mc/sec: 2489.79
//
Query:       EEA22512.1  [L=2080]
Description: fatty acid synthase subunit beta, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.7e-145  484.4   0.0   2.6e-145  483.8   0.0    1.3  1  DUF1729          Domain of unknown function (DUF1729)
    1.1e-51  176.2   0.0    1.1e-50  173.0   0.0    2.2  2  Acyl_transf_1    Acyl transferase domain
    6.4e-34  116.9   0.0    1.5e-33  115.7   0.0    1.7  1  FAS_meander      Fatty acid synthase meander beta sheet domai
    2.9e-28   99.2   0.0    5.8e-28   98.2   0.0    1.5  1  SAT              Starter unit:ACP transacylase in aflatoxin b
    3.4e-24   84.8   0.0    7.6e-24   83.6   0.0    1.5  1  MaoC_dehydratas  MaoC like domain
    1.4e-07   31.6   0.2    3.8e-07   30.1   0.2    1.7  1  FAS_N            N-terminal domain in fatty acid synthase sub
      5e-06   26.7   0.0    2.6e-05   24.4   0.0    2.2  2  MaoC_dehydrat_N  N-terminal half of MaoC dehydratase


Domain annotation for each model (and alignments):
>> DUF1729  Domain of unknown function (DUF1729)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  483.8   0.0    1e-148  2.6e-145       1     353 []     747    1089 ..     747    1089 .. 0.97

  Alignments for each domain:
  == domain 1  score: 483.8 bits;  conditional E-value: 1e-148
     DUF1729    1 piilqwtggraGGHHSledleaplletYakiRkqkNvvlvvGsGlgdaedsieyltGeWskelglppmPvdgillgsavmvakEaktseevkqlive 97  
                  pii+qwtggr+GGHHS+ed++ p+l  Y+kiR+ +Nv+lv+GsG+gd  +s++yltG+Ws+++g+ppmP+dgil+gs+vmvakEa+ts+ vk+li +
  EEA22512.1  747 PIIIQWTGGRGGGHHSFEDFHSPILRLYGKIRRYQNVILVAGSGFGDGIGSYPYLTGSWSVAYGYPPMPFDGILVGSRVMVAKEAHTSQTVKELICN 843 
                  79*********************************************************************************************** PP

     DUF1729   98 tpGvkdeeWeatykkpaGgvvsvrSelgepihkianraaklwkeldetifsleavekrkaalekkrdeiierlnkdyakpwfavdeegelveleemt 194 
                  tpG ++++W+++y++p Ggvv+v+Se+g+pihkia+r++ +wke+d++ifsl +++k+ aa+++++d+ii++ln+d+akpwf+ +++g++v+l +mt
  EEA22512.1  844 TPGTHEANWTKSYSEPIGGVVTVQSEMGQPIHKIATRGVLFWKEMDDKIFSL-PRDKQLAAIKARKDYIIRKLNEDFAKPWFCRNSKGDNVDLSDMT 939 
                  ****************************************************.999999************************************** PP

     DUF1729  195 YsevvrRlveLaflksrkewidpswkklfqdllqrveeRltaeehgeaesllesvealedPaeavetllaaypsaeaqlltaeDvawflqlvqrrgi 291 
                  Y e++ Rl+ L++l+s+ +wi+ps++ l++d++ r+ eRl+a        ++e +++ + P ++ + +l+++p+a+++ +++eDv+wfl+ ++rrg+
  EEA22512.1  940 YLEILSRLISLMYLPSQCRWINPSYEFLVRDVAVRILERLDA--------KCEIDNS-SRPDQLEKIFLQQCPKASTSIIHPEDVSWFLERCKRRGQ 1027
                  ****************************************33........3333333.4799*********************************** PP

     DUF1729  292 KPvpFvPvldedfeaffkkdslwqsedldavvdqdaqrviilqgpvavryitkvdepvkeil 353 
                  KPv+FvPvlde++ ++ kkdslwqsed++av+dqd+ rv++lqgpvav ++++ depv++il
  EEA22512.1 1028 KPVNFVPVLDENLATWMKKDSLWQSEDIEAVIDQDPGRVCVLQGPVAVTFSQQPDEPVADIL 1089
                  ************************************************************98 PP

>> Acyl_transf_1  Acyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0      0.16   4.1e+02     142     180 ..     384     422 ..     374     433 .. 0.81
   2 !  173.0   0.0   4.1e-54   1.1e-50       2     318 ..    1683    2068 ..    1682    2069 .. 0.96

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.16
                    H..TT.EEEEEEECCCCECCEEHHHHHHHHHHHHHCC.C CS
  Acyl_transf_1 142 rcqddvvgavansprrvvisgsqealrelvervskegvg 180
                      + +v++a  ns ++ +i+g+  +l ++ +  ++ gvg
     EEA22512.1 384 HLEKKVYLALSNSRSSFTIAGPASSLVRFNQLAHEIGVG 422
                    46789********************99998877666655 PP

  == domain 2  score: 173.0 bits;  conditional E-value: 4.1e-54
                     EEE--TT---TTTTCCHHHC-HHHHHHHHHHHHHCCHHHT--HHHHHHS--T.......................................... CS
  Acyl_transf_1    2 fvfsGqGsQwaGMGmeLlktskafaaviaradeafksqygfsvldvlrnnpe.......................................... 53  
                     ++f+GqGsQ  GMGmeL+k+s+++++ ++  d+ + ++yg+s+l+++++np+                                          
     EEA22512.1 1683 YIFTGQGSQAPGMGMELYKSSPVAKKIWDDIDRYLLENYGWSILKMVQENPKshtiyfsgkrgrairdrylsmtvssigpdgqvvttplleglt 1776
                     9********************************************************************************************* PP

                     ............TGGGSHHHHHHHHHHHHHHHHHHHHHTT..-TTSEEEE-TTHHHHHHHHCCSSSHHHHHHHHHHHHHHHHHHTS-EECCEEC CS
  Acyl_transf_1   54 ............glldaiqfvqpaLaavqialaellkskG..vrpaavvGHSlGElAaavvagalsseeallavvlrsrlmmqlagpgdmaave 133 
                                 gll a+qf+qpa+a++++a +e+++  G  ++ a+++GHSlGE  a++      ++     ++++++l+m++a+++d  + +
     EEA22512.1 1777 pnarsftfedskGLLYATQFAQPAIAVLEKATFEDMRENGliQEGALFAGHSLGEFGALACQVEFLPFQQQIDIAFYRGLTMHNAVKRDSTGAT 1870
                     ****************************************99999************************************************* PP

                     S.HHHHHHH..TT.EEEEEEECCCCECCEEHHHHHHHHHHHHHCC.CCEEECCCEECTTCCCCCCCCHH.HHHHHHCCCHHCHHTTBEHCCCHH CS
  Acyl_transf_1  134 laeeeeklrcqddvvgavansprrvvisgsqealrelvervskegvgalvenvnvavhspqvdaiadal.asaladiaprkpkvakisstslde 226 
                     +               +va +p+rv   + ++alr+lv  ++ e    l e+vn++v+ +q+++++++  + ala+i ++ ++++  ++   + 
     EEA22512.1 1871 D-------------FSMVAVNPGRVNKPFDEAALRRLVDIIANES-ERLLEIVNFNVEGEQYVCAGHNAnLYALAQILNQVSRMPTEQIALWSR 1950
                     *.............******************************9.99******************9761568999999999999988887777 PP

                     H................HHHCHHHHHHHHHHHCHCCHCCHHTTS.SSECC-CCEECSSSSCCHCCCCCCCHH.......GGG-TCCCCCCTEET CS
  Acyl_transf_1  227 s................serelsaeywvanlrspvrfaeavlsa.aetiplvfveispHslllaalektlks.......aedvksatlvGklkr 296 
                     +                s++ +   + +a+ +   ++++ +ls+  +tipl ++++++Hs  l+ ++ + ++        ed+++   + ++ +
     EEA22512.1 1951 EsvvvegaqqqdkpyspSTTAVNTMIYNAIHSAHKLPKPIILSRgQATIPLQGIDVPFHSAQLRSGVPAWRKfllsrihPEDIEPDDFLDRFVP 2044
                     779999*********988888888888888999999***********************************99*9999999************* PP

                     TSS-..HHHCHHHHHHHHHHCT-H CS
  Acyl_transf_1  297 dltd..flvtflyllakahltgse 318 
                     ++ +  f  + +y ++ +++ gse
     EEA22512.1 2045 NVMGrpFSLDREYVAEAMQVMGSE 2068
                     **9999999999999999999986 PP

>> FAS_meander  Fatty acid synthase meander beta sheet domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.7   0.0   5.8e-37   1.5e-33       2     146 .]    1146    1287 ..    1145    1287 .. 0.91

  Alignments for each domain:
  == domain 1  score: 115.7 bits;  conditional E-value: 5.8e-37
  FAS_meander    2 selpseeewlellageelsWlralltsetivqgkklveNPlrrllaprkgqlveieeadspektvvtvkeakesg.elkkaveiklsedkeIsvtl 96  
                   ++lp++ee l++la+++++W+ra+l s++i+q+++ ++N l+  ++++++++vei+ea+     ++ vk a + g ++++ ve++  ++ +I+ ++
   EEA22512.1 1146 RTLPTPEESLQYLASRTHGWMRAVLLSDFILQDRAKRANFLQGSFELDDKKTVEIDEANG----RMLVKTAVDGGkHQRTLVEMSSADGISIAAQV 1237
                   589****************************************************98877....334444444441556789************** PP

  FAS_meander   97 ieertaegesvpLeleFeYkpetglapIhEvmegrndrikeFYwklWfge 146 
                   ++++ +++++++L+l+F+Y+p+++l+p++E m++rn +ik+FY++lW+g+
   EEA22512.1 1238 LHYSPDRQTPTALHLKFQYNPRNSLYPLTEDMQDRNMQIKSFYSRLWLGS 1287
                   ************************************************95 PP

>> SAT  Starter unit:ACP transacylase in aflatoxin biosynthesis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.2   0.0   2.3e-31   5.8e-28       2     239 ..     181     436 ..     180     437 .. 0.89

  Alignments for each domain:
  == domain 1  score: 98.2 bits;  conditional E-value: 2.3e-31
         SAT   2 lFGDq.tad..vlpeLrkLlqakenplLrsFLekasealraeisrlpaaerkslp.....rftslqellerysesglkspalssallciaqlaqfivy. 91 
                 +FG+q  ++  ++ +L++L+ +++ plL  ++ ++ ++l +     p + r+++        ++l+ + + ++e+ l+++a+s++  +++ la+++v+ 
  EEA22512.1 181 IFGGQgASNprCFRDLQDLY-NTYAPLLDVLISTVDNVLYELCVL-P-ETRDFFRgrqicLLSWLKTPHTVPDEQFLATAAVSFVIHGVVALAHWCVTc 276
                 8****844458*********.*******************98885.4.67777777776566************************************7 PP

         SAT  92 ..leenpeeypspestylvGlCtGllaAaavacskslseLvplaveavrvafrlGlevarvaarle.........egsssssesWslavtglseeelek 179
                   l+++p ++ s    +  G+++G++ Aaav++s+s++++++ +v  ++++f++G+e++r+a rl+         e++ + + s +l ++gl ++++ +
  EEA22512.1 277 nvLGKHPGTLRSL-LAGTSGHSQGIIIAAAVSASDSWKSFYENSVLCMKLLFWTGYESHRAAPRLAltsaavhdaESRGEGQPSHMLHISGLLKKHIIS 374
                 7667777777764.4599******************************************888888888888888666677777999************ PP

         SAT 180 alaefneekglppasrvyisavssss.vtisGpPstl...eallksskakkkkkksklpiyapy 239
                 +l + n++ +l+  ++vy ++ +s s +ti+Gp s+l   ++l ++    +k ++s++p+ +++
  EEA22512.1 375 LLGKCNQDIHLE--KKVYLALSNSRSsFTIAGPASSLvrfNQLAHEIGVGRKVDQSRIPFDKRK 436
                 ********9955..**********888**********99999999999***********99876 PP

>> MaoC_dehydratas  MaoC like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.6   0.0     3e-27   7.6e-24      19     108 ..    1563    1653 ..    1546    1667 .. 0.90

  Alignments for each domain:
  == domain 1  score: 83.6 bits;  conditional E-value: 3e-27
                       E.HHHHHHHHHHHT---GGGT-HHHHHHTTTSSSB--HHHHHHHHHHHHHHHHSTTEGGGEEEEEEEE-S--BTTCEEEEEEEEEEEEEEE CS
  MaoC_dehydratas   19 t.eadialyalvsgDlnpiHvdpefAkkagfggpIahGmltlaivaklveeelgdnvvarvgeikvrFtkpVlpgdtlkvelevvgkrdvr 108 
                       + + d++lya vs D+npiHv+p f+  a+++g+I+hGm+t+a+ ++++ + + d +  r++ ++v+F+++Vlpg++++ +  + ++ +++
       EEA22512.1 1563 KmPCDNELYAKVSKDYNPIHVSPVFSTIANLPGTIVHGMYTSAVTSAVLDQVANDFNHVRTRRYTVSFVDMVLPGEEVELRYRHIAMLQGK 1653
                       35889****************************************************************************9999887765 PP

>> FAS_N  N-terminal domain in fatty acid synthase subunit beta
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.1   0.2   1.5e-10   3.8e-07       5     126 ..      42     151 ..      40     153 .. 0.88

  Alignments for each domain:
  == domain 1  score: 30.1 bits;  conditional E-value: 1.5e-10
       FAS_N   5 lslthgslevsilvpaslylaaeqLrdeFtatlvapseeleqeeeplseieLlakFLgyvaksiestesstsqfedvlklvleefessyLkkndihalv 103
                 +sl +  le+s ++ +++ +   q r  F  +l +ps++l +   p ++  Ll +FL++  ++++st         ++  ++  f++++L  ndih+l+
  EEA22512.1  42 FSLVYKGLEYSTPLLSNHAIDLSQHRAIFLSSLEEPSDNLTEA--PTAVESLLIRFLQFLLDRQAST--------TLILPLVVAFRRDFLLLNDIHSLI 130
                 68889999******9**********************776665..777778***********87777........566667778*************** PP

       FAS_N 104 snLpsettllakkeviraYykal 126
                  +Lp    l  +  +++ Yy+++
  EEA22512.1 131 ASLP--EPLETQRALLCTYYTTI 151
                 ****..56899*********986 PP

>> MaoC_dehydrat_N  N-terminal half of MaoC dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       1.8   4.5e+03      92     131 ..    1047    1087 ..    1043    1087 .. 0.81
   2 !   24.4   0.0     1e-08   2.6e-05      50     130 ..    1338    1420 ..    1322    1422 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 1.8
  MaoC_dehydrat_N   92 DelttesriadvydkkgvGalefiv..vettvtnqrGepvat 131 
                       D+l  ++ i++v d++  G ++++   v  t++ q +epva+
       EEA22512.1 1047 DSLWQSEDIEAVIDQD-PGRVCVLQgpVAVTFSQQPDEPVAD 1087
                       88888999******99.7****99844567778899999986 PP

  == domain 2  score: 24.4 bits;  conditional E-value: 1e-08
  MaoC_dehydrat_N   50 Pptflivlatkap...ellealgidlsrllhgeqefey...hepiraGDelttesriadvydkkgvGalefivvettvtnqrGepva 130 
                       P   +i+ a++a     + +++++dl rl+h++ efe+   + p+r G+++ ++s+i+++      ++++ + v+++++ ++++pv+
       EEA22512.1 1338 PLNATIIPAWEALvqpLMVPEIDGDLLRLVHLSIEFELfpkATPLRIGETVEVSSHIQSIVID---DKGKTVAVRAVIS-RDNQPVV 1420
                       5555566667665553566*******************88788*******************6...799********99.8888886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2080 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       440  (0.0245412); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 1.17u 0.31s 00:00:01.48 Elapsed: 00:00:00.54
# Mc/sec: 11675.01
//
Query:       EEA22513.1  [L=887]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.4e-10   39.9   9.8    7.3e-10   38.8   9.8    1.6  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
    0.00031   19.9   2.0    0.00031   19.9   2.0    1.8  2  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.8   9.8   8.1e-14   7.3e-10       2      35 ..      26      58 ..      25      63 .. 0.90

  Alignments for each domain:
  == domain 1  score: 38.8 bits;  conditional E-value: 8.1e-14
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCT CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfyse 35
                aCd+Cr +Kv+Cd++ P+Cs+C+k ++ C+ ++ 
  EEA22513.1 26 ACDQCRNRKVRCDRQLPQCSSCEKAGVLCE-FPT 58
                9*****************************.554 PP

>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   2.0   3.5e-08   0.00031       1     185 [.     257     439 ..     257     526 .. 0.84
   2 ?   -2.0   0.1      0.16   1.5e+03      25      66 ..     509     558 ..     485     619 .. 0.58

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 3.5e-08
  Fungal_trans   1 ldrffsnfhpqfpilhkpsflpkt....ssenssksayaspllllailalGalfsesetkesnssltsesqefiafpl..raeilihedfsspsssl 91 
                   l++f + f+   pi+++ s+ +      +  ++sk ++a +l ++ i+ l++ +    ++ ++s  + +  e +  +l  ++++l h +f+ +++  
    EEA22513.1 257 LQLFLDKFNAVTPIFNESSLREIIkaqyNPGPDSKPDEAYNLCFNNIIVLASGLRARLARLDKSYPKAMNEELLPAFLanSFRALHHLKFFLQPR-H 352
                   68999************888888887667777777777777777888888888888888887777777664444444444667777888888888.8 PP

  Fungal_trans  92 wilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpL 185
                     lq+L  l+l+   + +   + +++ +a+ l + +   + p ++         ++ +e++r l+w+ F++Dk+  ++ G p+ l+ +  +lpL
    EEA22513.1 353 VNLQALATLALVAREYHESCVFDMICHMACDLFKAMDSEQSPMSKV------DHPN-FEEWRTLYWTLFVMDKQRTSVNGLPFDLYFYHSDLPL 439
                   89***********99999999999****************999998......8888.9999**********************65666666665 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.16
  Fungal_trans  25 ssenssksayasplll........lailalGalfsesetkesnssltses 66 
                   s + ++  +++++ll+        +  +++++ + +s++ +++s++ + +
    EEA22513.1 509 STNDNNGENNNNNLLVednwqvelNYAYHIAQVLIHSRSDTTQSKEIELK 558
                   33334444444444445555555556666666666666666666666544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (887 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       738  (0.0411624); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.72u 0.33s 00:00:01.05 Elapsed: 00:00:00.49
# Mc/sec: 5414.57
//
Query:       EEA22514.1  [L=361]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.1e-68  227.9  12.7    1.2e-67  227.5  12.7    1.1  1  RTA1      RTA1 like protein


Domain annotation for each model (and alignments):
>> RTA1  RTA1 like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  227.5  12.7   6.7e-72   1.2e-67       2     206 ..      94     310 ..      93     311 .. 0.98

  Alignments for each domain:
  == domain 1  score: 227.5 bits;  conditional E-value: 6.7e-72
        RTA1   2 ilGcileviGYigRilsakn.tskaslgpfiiqivllllaPafiaaaiYmllgrlilllgeelsllrpklytkiFvvlDvvslllqaaGGglaasasss 99 
                 i+G++le+iGY+gR++++++ ++   ++ f+i++v+l++aPaf++a iY++l+r+i+++ge+ls+++p++yt++F+++D++slllqa+GG++a+ a++ 
  EEA22514.1  94 ICGLALEIIGYAGRVMINQSpFD---KNNFLIYLVCLTIAPAFLSACIYLCLARIIVVYGESLSRFKPRFYTIVFCTCDFISLLLQAIGGAIASIATDY 189
                 89******************666...************************************************************************9 PP

        RTA1 100 aeaklGeniiiaGlalQvvvlvvFlllaldFllrvr..............kskkfkkfllalyaavlliliRsiyRvvElaeGwdgylithEvyfyvLd 184
                 ++++lG +i+i+Gl++Qv++lv+F++l+ dF++rv               +s+ f  fl  l + +l+i+iRs++Rv+El++G++g+l+++E++f+vL+
  EEA22514.1 190 TTTQLGIHIMIGGLSFQVFSLVLFIILCSDFAYRVWrspfhwdtsrkevfESRIFMFFLGGLSLGTLTITIRSCFRVAELSGGFHGNLANNEATFMVLE 288
                 99************************************************8899********************************************* PP

        RTA1 185 allillavvllnvfhpgrlfkk 206
                 +++i +a ++l+++hpg +f++
  EEA22514.1 289 GAMIGIASICLTALHPGVAFRG 310
                 ******************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (361 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       585  (0.0326287); expected 358.6 (0.02)
Passed bias filter:                      309  (0.0172346); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2495.29
//
Query:       EEA22515.1  [L=349]
Description: diacylglycerol pyrophosphate phosphatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.1e-25   88.1   0.2    4.1e-25   88.1   0.2    2.4  2  PAP2           PAP2 superfamily
  ------ inclusion threshold ------
       0.02   14.6   5.2      0.091   12.4   0.1    2.7  3  PAP2_3         PAP2 superfamily
       0.44   10.2   3.8        1.5    8.5   0.8    2.6  2  Cation_efflux  Cation efflux family


Domain annotation for each model (and alignments):
>> PAP2  PAP2 superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.3      0.26   1.6e+03     112     132 ..      59      79 ..      54      83 .. 0.76
   2 !   88.1   0.2   6.9e-29   4.1e-25       2     132 ..     105     300 ..     104     303 .. 0.95

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.26
        PAP2 112 DvlaGlliGialaalayrlvq 132
                 +v++G++ ++++a++++ ++ 
  EEA22515.1  59 AVVCGVIPAGIIAFVCCSIAA 79 
                 688899988888888887665 PP

  == domain 2  score: 88.1 bits;  conditional E-value: 6.9e-29
        PAP2   2 llalllalalaalltsvlKdlvgrpRPfflaeetkldtqvstletses...........................keakesfPSgHsafafalalllal 73 
                 +l l+l+ ++a ++ +++K+lvg+pRP+fla++++++ + s+ +++ +                           +++++sfPSgH+++afa++++l+l
  EEA22515.1 105 WLGLGLSFVAAFFFAQAVKNLVGKPRPDFLARCNPDSANESA-YALGNynpegpvlvdwqicqtkngggvgisefNDGFRSFPSGHTCIAFAGLVYLSL 202
                 78899**********************************665.5555579**********************9999999999***************** PP

        PAP2  74 llrrkrkkig........................................lvllalillllavlvalsRlylgvHflsDvlaGlliGialaalayrlvq 132
                 +l+ k++  g                                        lv+++l+++++a+++a +R+ +g H+ +Dv+++ +iG ++++l +rl++
  EEA22515.1 203 WLAMKFSV-GipilysdrtaqvpkdasfqrgdihdeasslrrqnaapplyLVAIILVPFAVAIYIATTRYQDGKHHGFDVVFSSIIGSICGYLGFRLYH 300
                 ****9999.779*********************************************************************************999886 PP

>> PAP2_3  PAP2 superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.1       1.3   7.8e+03     154     161 ..      15      22 ..       6      41 .. 0.54
   2 ?   12.4   0.1   1.5e-05     0.091     113     149 ..     171     207 ..      56     217 .. 0.76
   3 ?    4.3   0.2    0.0047        28     153     187 ..     255     291 ..     242     294 .. 0.60

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 1.3
      PAP2_3 154 lalllnvl 161
                 ++l+l+v+
  EEA22515.1  15 VILILFVA 22 
                 22222222 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 1.5e-05
      PAP2_3 113 avllrgtienglaafPSlHvawallvalalwrlrrkr 149
                   ++ + +++g+ +fPS H+++a+  +++l  +   +
  EEA22515.1 171 GGVGISEFNDGFRSFPSGHTCIAFAGLVYLSLWLAMK 207
                 456667889**************98888776665555 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.0047
      PAP2_3 153 vlalllnvlmivat..vatgnHYlvDviaGvalalva 187
                 ++++ ++v++ +at     g H   Dv+++ +++ ++
  EEA22515.1 255 IILVPFAVAIYIATtrYQDGKHHGFDVVFSSIIGSIC 291
                 3333344444433311567888888888888887766 PP

>> Cation_efflux  Cation efflux family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.8   0.00026       1.5     106     164 ..      64     119 ..      15     128 .. 0.83
   2 ?    1.9   0.1     0.027   1.6e+02     157     190 ..     261     298 ..     191     300 .. 0.80

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00026
  Cation_efflux 106 alvvalvslvvnlalllilrragrklrsaalkaaalhvlgDaltslgvlvsalvillfn 164
                    ++  +++++v + + ++  rr+  +lr ++l+ +++++l+   ++lg  +s++ +++f 
     EEA22515.1  64 VIPAGIIAFVCCSIAAWRARRVDVHLRGQVLRRELWEWLT---GWLGLGLSFVAAFFFA 119
                    4567899********************************9...7777777777777774 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.027
  Cation_efflux 157 alvillfnlksg....plaDpvaslligliilysalkl 190
                    a+ i++ +   +    + +D v+s +ig i  y +++l
     EEA22515.1 261 AVAIYIATTRYQdgkhHGFDVVFSSIIGSICGYLGFRL 298
                    23333333333356778999999999999999999886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (349 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       469  (0.0261587); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 2210.02
//
Query:       EEA22516.1  [L=216]
Description: hypothetical protein PMAA_091440 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.9e-13   50.2   0.5    5.9e-10   39.3   0.0    2.8  3  Sulfotransfer_4  Sulfotransferase domain
  ------ inclusion threshold ------
      0.021   15.2   0.0      0.033   14.6   0.0    1.4  1  Sulfotransfer_3  Sulfotransferase family


Domain annotation for each model (and alignments):
>> Sulfotransfer_4  Sulfotransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.3   0.0   6.6e-14   5.9e-10      65     115 ..      13      64 ..       4      79 .. 0.87
   2 !    8.0   0.0   0.00025       2.2     154     185 ..      80     114 ..      65     119 .. 0.82
   3 ?   -0.5   0.0     0.099   8.9e+02     116     150 ..     152     186 ..     133     198 .. 0.71

  Alignments for each domain:
  == domain 1  score: 39.3 bits;  conditional E-value: 6.6e-14
  Sulfotransfer_4  65 llggydavvdvpaalfaeelleayPdakvIlteR.dpekWlksmkktllalr 115
                      + ++yd + d+p+a+ ++el+ a+Pdak+Ilt R  +++Wl+s+ k+ ++  
       EEA22516.1  13 YAQNYDILEDLPWAIAYRELATAFPDAKFILTSRaTESAWLESIGKHNERRK 64 
                      5689******************************99999*****99988765 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.00025
  Sulfotransfer_4 154 aedeeaakeayeehnervrevvp...aerlLvykv 185
                      ++ +++  +ay++hne vr+ +    +erlL++ v
       EEA22516.1  80 EKCKKKYLDAYRAHNEGVRDFFDkegKERLLELVV 114
                      467888999*************9888999*99866 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 0.099
  Sulfotransfer_4 116 setlsrllalldpllellaklvellralvrrlfga 150
                      ++ ++r l l+ + + ++ kl +l+ +l ++++g+
       EEA22516.1 152 RSGWWRKLGLFPENNTVTGKLGKLWSKLQHAWVGT 186
                      34566667777777778888888888887777665 PP

>> Sulfotransfer_3  Sulfotransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.0   3.7e-06     0.033     116     190 ..      29     111 ..       3     115 .. 0.64

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 3.7e-06
                      HHHHHHHBSSEEEEEEE--H.HHHHHHHHHTT--------.......--..-.HHH.HHHHHHHHHHHHHHHHHHHS-TTSEEE CS
  Sulfotransfer_3 116 ldlllelfPdAkfihlvRdpvdtvlssyvslfgkkresys.......edsld.ele.daleewarayerllaararlppdrfld 190
                        +l+ +fPdAkfi + R   ++++   +  +++ r++ +       ++  + + + + l+ ++ + e  +++ ++ +++r+l+
       EEA22516.1  29 YRELATAFPDAKFILTSRAT-ESAWLESIGKHNERRKWIGnkkvfgcKKASGeKCKkKYLDAYRAHNEGVRDFFDKEGKERLLE 111
                      4789**************99.666655555545555555565555553333335554555555555555555555566666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (216 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      306  (0.0170673); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1437.80
//
Query:       EEA22517.1  [L=614]
Description: hypothetical protein PMAA_091450 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.6e-43  146.7   3.6    2.4e-42  145.1   3.6    1.9  1  Glyco_trans_2_3  Glycosyl transferase family group 2
  ------ inclusion threshold ------
       0.16   12.3   0.6       0.38   11.1   0.1    2.0  2  Wzz              Chain length determinant protein
        2.7    7.0   7.7       0.16   11.0   1.6    1.8  2  ABC2_membrane_3  ABC-2 family transporter protein


Domain annotation for each model (and alignments):
>> Glyco_trans_2_3  Glycosyl transferase family group 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.1   3.6     4e-46   2.4e-42       1     196 [.     272     508 ..     272     509 .. 0.85

  Alignments for each domain:
  == domain 1  score: 145.1 bits;  conditional E-value: 4e-46
  Glyco_trans_2_3   1 iilllDaDtvlppdclrei....aaelaspevaivqgpvlvmnvanwleelaalffaedhgkdilvrealgrvvpsvGsgaflrrsalqevggw 90 
                      ii+++DaDt+l +++++ei    +a+l++ e++++++p+l+++ ++  + + + + ++++++++++++++g++v++++s+++l+++++++vggw
       EEA22517.1 272 IITVMDADTHLVQEYFLEIrslhYAHLDTSERHLYCCPILFDR-NSSETPVLVRCADIMWAFAGISTMYPGSPVSIPTSVYSLPIQLANKVGGW 364
                      79*****************88777788888***********95.57888999999999************************************ PP

  Glyco_trans_2_3  91 dgdessvsEDfdmglrlq.rkGyrv....rfvpeslvkeksplt..........lraalrQrkRwayGc......eleklil............ 151
                      d+d+++++ED++m+l+++ + G  v    ++vp+s+++ +s +           +r +++Q+ R+++G+            +            
       EEA22517.1 365 DSDPTAIGEDMHMMLKCYfETGGSVitltVHVPASQCNVSSGYPvdgwrrsldiCRNRYKQALRHMWGAldtgyaV-----Rhsvpvsisskrt 453
                      *****************747776655666899999********97888888888888888********96544440.....3444444455555 PP

  Glyco_trans_2_3 152 ......lvrllgylgsllwsa..lplhlallllfsllalalvl...llllllaall 196
                            + +l+  l++llw+a  lp+hla++l+fs++++ +v+   l+++l++a+ 
       EEA22517.1 454 tfwpfpR-VLHLALAHLLWEAhfLPCHLAVMLIFSVVYTTFVPldtLHPTLAWAFS 508
                      4544433.3557789999988879******************9999*******996 PP

>> Wzz  Chain length determinant protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.1   6.4e-05      0.38      21      55 ..      15      49 ..       2      81 .. 0.84
   2 ?   -3.6   0.1       2.4   1.5e+04      24      37 ..     481     494 ..     471     495 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 6.4e-05
                XXXXXXXXXXXXXXXXXXX-EEEEEEEES--CHHH CS
         Wzz 21 lvtllfallaviyaflatpkYtataqilvpekkqv 55
                +++l  +l+a++ a ++ p++t++  +++p +++ 
  EEA22517.1 15 IIALMLLLVAAFPATIQLPWWTSDLAVQQPAPSSH 49
                67888889999999****************99875 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 2.4
                 XXXXXXXXXXXXXX CS
         Wzz  24 llfallaviyafla 37 
                 +++++++v+y+ ++
  EEA22517.1 481 AVMLIFSVVYTTFV 494
                 57788899998554 PP

>> ABC2_membrane_3  ABC-2 family transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.5      0.17     1e+03     299     325 ..       5      58 ..       2      85 .. 0.57
   2 ?   11.0   1.6   2.7e-05      0.16     275     327 ..     481     536 ..     477     539 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.17
  ABC2_membrane_3 299 wifsiiPffapglgllrli......tgdplwe.....................i 325
                      w+++ +P f+++ ++l l+       + p+w+                     +
       EEA22517.1   5 WASRCLPGFSIIALMLLLVaafpatIQLPWWTsdlavqqpapsshegkhermrF 58 
                      777777777777777777656555433355556666666666666666666663 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 2.7e-05
  ABC2_membrane_3 275 ivilllsgffgglfpledlpsalkwifs...iiPffapglgllrlitgdplweill 327
                      +v+l++s++++ ++pl++l+ +l+w+fs   +i + +++ + ++l  +d++ +i+l
       EEA22517.1 481 AVMLIFSVVYTTFVPLDTLHPTLAWAFSvanLIRTLSFIGMNINLTIYDQWHQIWL 536
                      799**********************7664448999999999999999898999995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (614 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       646  (0.036031); expected 358.6 (0.02)
Passed bias filter:                      442  (0.0246528); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.43
# Mc/sec: 4276.76
//
Query:       EEA22518.1  [L=442]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-07   31.8  12.5    1.8e-07   31.2  12.5    1.3  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
    0.00015   20.7   0.1    0.00021   20.3   0.1    1.2  1  Fungal_trans_2  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.2  12.5     2e-11   1.8e-07       2      35 ..      24      56 ..      23      61 .. 0.92

  Alignments for each domain:
  == domain 1  score: 31.2 bits;  conditional E-value: 2e-11
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCT CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfyse 35
                +C +C+ ++ KCd++ P+CsnCk++nl+C  y++
  EEA22518.1 24 GCGQCKARRKKCDERPPTCSNCKRRNLKCD-YED 56
                7****************************9.765 PP

>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.1   2.3e-08   0.00021       2      98 ..     150     244 ..     149     287 .. 0.81

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 2.3e-08
  Fungal_trans_2   2 lldyyldnvapllspvpes...snpfrkvllplalsnkallhallalsafhlqskgpkds..lereakrykslalkelqealaelsstlsrneky 91 
                     l+ ++l+n + +l   p++     +++++ + +a++++++ h+lla s++h ++++p++s  +     +++  a+++++e  +  +         
      EEA22518.1 150 LMFHFLTNASHTL--APDNagvFQYWQQIAYSIAQEHDFVRHTLLAYSSLHIAHLQPQESqkYVVLTSHHHAIAINGFKEQVTAINGGNC----- 237
                     5568888888844..44445589*****************************99999998887778888888899999988888877777..... PP

  Fungal_trans_2  92 kdiLaai 98 
                     ++i++  
      EEA22518.1 238 DAIFIFS 244
                     5555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (442 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       612  (0.0341346); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.47
# Mc/sec: 2831.02
//
Query:       EEA22519.1  [L=404]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.7e-20   72.8   0.1    4.4e-20   72.1   0.1    1.3  1  CDH-cyt         Cytochrome domain of cellobiose dehydrogenase
    6.3e-08   32.9  10.1    6.3e-08   32.9  10.1    3.1  3  Cytochrom_B561  Eukaryotic cytochrome b561
     0.0037   17.0   5.9     0.0037   17.0   5.9    2.4  2  DUF2427         Domain of unknown function (DUF2427)


Domain annotation for each model (and alignments):
>> CDH-cyt  Cytochrome domain of cellobiose dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.1   0.1   7.4e-24   4.4e-20      13     177 ..      33     194 ..      22     196 .. 0.81

  Alignments for each domain:
  == domain 1  score: 72.1 bits;  conditional E-value: 7.4e-24
                 ETT-SS-EEEEEEB-CCCTS--SEEEEEEEEE-GCS--EEEEESSSSSCTSEEEEEEEE..TTEEEEEEEEBSSSSS-EE--SS-EEEEEE.EEE-SSE CS
     CDH-cyt  13 ytdeaggftfgialPedattdatefigqlvaplsakagWaGislggsMtnnlLlvaWpn..gnevvtSfrlatgyasPevytgdakltqlsgtsvnath 109
                  ++ +g++tf +   + a  +++ +  + + p+s    ++Gi+ g+ M+++l++v++ n  g+ +++S+r+atg  +P+ +  +  ++ l+g+++++  
  EEA22519.1  33 LQSGSGNVTFALSASDPA-VSQDVYFHL-SGPSS--YSYIGIGTGTVMQGSLIFVMYSNatGDGITLSPRIATGNKEPVLV-PSLDVEILPGSNTSDGL 126
                 455567777777665555.667888887.****9..***********************999*******************.999************** PP

                 EEEEEEEET-SEEEETTEEEE--TTTEEEEEEEE...ESS--B.STTSCCCB-----SEEEEEEEE--CCB- CS
     CDH-cyt 110 ftltfrCqgClsweqggtsgsastssnlvlgwAq...skkapt.npaspdstlsqHdngfgqfgadlsaaks 177
                 +t+++rC++C sw+ gg  + ++  ++  + +A+    +++++ +++s +++l++H + +g f++d++ a++
  EEA22519.1 127 MTVNARCKNCHSWN-GGALNLSD--TAYPWNYALgpnTAQSVKlKSNSLSANLEMHVE-YGLFTLDMTRATA 194
                 *************6.44333333..78889999965334447745555555******9.********99875 PP

>> Cytochrom_B561  Eukaryotic cytochrome b561
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.3      0.34     2e+03      49      98 ..      10      60 ..       3      94 .. 0.57
   2 ?    2.6   0.0     0.023   1.4e+02      69     130 ..     134     198 ..     126     202 .. 0.66
   3 !   32.9  10.1     1e-11   6.3e-08       1     132 [.     227     351 ..     227     355 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.34
                    HHHHHHHHHHHHHHHT.--SS-SHHHHHHHHHHHHHHHHHHHHHHHHTSS- CS
  Cytochrom_B561 49 avvgllavfkskneke.ianlyslHswlGlvtvilfllqlvlGfvlfllpk 98
                    +++++++    +n+k  ++ ++sl s  G vt++l +   +++  ++++ +
      EEA22519.1 10 VLFSFFISALCQNDKSaAVFISSLQSGSGNVTFALSASDPAVSQDVYFHLS 60
                    444444444444444314566778888888888777766555555555444 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.023
                     -SHHHHHHHHH.HHHHHHHHHHHHHHHTS..S---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Cytochrom_B561  69 yslHswlGlvt.vilfllqlvlGfvlfll..pklskklralllplHvllGlvifvlaivtallGl 130
                     ++ Hsw G +  +  ++  + +++    +   kl+ +  ++ l +Hv  Gl+++ +  +ta+ G+
      EEA22519.1 134 KNCHSWNGGALnLSDTAYPWNYALGPNTAqsVKLKSNSLSANLEMHVEYGLFTLDMTRATATGGV 198
                     678999876541444555555555555550055555555555556*******9999999988776 PP

  == domain 3  score: 32.9 bits;  conditional E-value: 1e-11
                     HHHHHHHHHHTHHHHHHHTHHHHS-S...-HHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHT--SS-SHHHHHHHHHHHHHHHHHHHHHHHH CS
  Cytochrom_B561   1 lHpvlmviGfvllmgeaiLvyrvsstrklskktkkllHlilqllalilavvglla.vfksknekeianlyslHswlGlvtvilfllqlvlGfvlf 94 
                     lH+vl +i +v++   +++  r   +       + + H++ q+l+ +++++g ++ +f s+  ++++ + s+H +lG v v+ +l+q++lG    
      EEA22519.1 227 LHAVLATIPLVFFLPTGVIFLRF--F-----PGSVRWHWVSQTLSSVVSILGSAVgIFLSTLFNKASSFGSTHQILGYVIVAGVLVQWFLGYWHH 314
                     69999999999999999999998..4.....55899***********9999976537888888899*************************9998 PP

                     TSS---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Cytochrom_B561  95 llpklskklralllplHvllGlvifvlaivtallGlle 132
                      + k ++  ++ +  +H+ lG +if +ai++a +Gl+ 
      EEA22519.1 315 RIYKKEQ-RTTNYAFVHRNLGHIIFFFAIANAGIGLTW 351
                     8777666.45667788*******************965 PP

>> DUF2427  Domain of unknown function (DUF2427)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.0   5.9   6.2e-07    0.0037      19      99 ..     226     310 ..     220     315 .. 0.80
   2 ?    2.3   0.2     0.024   1.5e+02      58     101 ..     307     350 ..     304     354 .. 0.81

  Alignments for each domain:
  == domain 1  score: 17.0 bits;  conditional E-value: 6.2e-07
     DUF2427  19 wvHiilmtlalvvvyPvalvLsla...ksrwylpvqivnlvlavlg....lllghiykgstPelypnniyaklswillillavqvvla 99 
                 ++H++l t+ lv+ +P+++++      + rw+ + q++++v+ +lg    ++l  ++++++ ++  ++ ++ l+ +++  ++vq++l+
  EEA22519.1 226 ILHAVLATIPLVFFLPTGVIFLRFfpgSVRWHWVSQTLSSVVSILGsavgIFLSTLFNKAS-SF--GSTHQILGYVIVAGVLVQWFLG 310
                 57*****************9865423268**********9998876111155555677776.55..9******************998 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.024
     DUF2427  58 avlglllghiykgstPelypnniyaklswillillavqvvlavl 101
                  +lg+    iyk+++       ++++l+ i++++ ++ + ++++
  EEA22519.1 307 WFLGYWHHRIYKKEQRTTNYAFVHRNLGHIIFFFAIANAGIGLT 350
                 57888899999988866555789***********9999888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (404 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       801  (0.0446762); expected 358.6 (0.02)
Passed bias filter:                      483  (0.0269396); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 2690.46
//
Query:       EEA22520.1  [L=269]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.8e-07   29.6   0.2    2.1e-06   27.8   0.2    2.0  1  NAD_binding_10  NAD(P)H-binding
  ------ inclusion threshold ------
      0.078   12.5   0.0       0.15   11.6   0.0    1.5  1  HTH_24          Winged helix-turn-helix DNA-binding
       0.13   11.9   0.0       0.22   11.1   0.0    1.4  1  CinA            Competence-damaged protein
       0.17   11.1   0.0       0.34   10.2   0.0    1.5  1  CcmH            Cytochrome C biogenesis protein


Domain annotation for each model (and alignments):
>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   0.2   4.6e-10   2.1e-06       1     179 [.       9     248 ..       9     253 .. 0.69

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 4.6e-10
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCH.HHHCTT.........TCEEEE--TT-CCHHHHHHT...........T-SEEEES---TCCH CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpekla.eleaee.........glevvegdvtdvedlaealk...........gadaVvsalggggkd 74 
                     GAtG+   + ++ ll  ++++  al+R+p+kl  +l++++         +l++v+gd+t ++d++++l             +da+vs +g+  ++
      EEA22520.1   9 GATGGCTNACLASLLLFSDYQAIALARTPQKLIdSLKKQPgitdavlaeRLHIVKGDATVAADVKRTLLfqaddgkteskLVDAIVSGIGAYPQR 103
                     99**999999999998889************953344333333333333899***************977777877777789*******887774 PP

                     HHH................HHHHHHHHHH.......CT--EEEEEEETTTTSGCGCH....HHH.HHHHCCHHHHHHHHHHHHHHHH...SSSE. CS
  NAD_binding_10  75 eeg................aknivdaake.......agvkRfvlvsaigvgdevpge....fge.wnkellkaylaakraaeellra...sgld. 137
                     ++g                + ++v a++e       ++   + ++s+ g    +  +    fg  + ++ll++ +++k+++ee++ +     l  
      EEA22520.1 104 KKGtlltfemdnpkiteqsTTALVSAMREihaeqhpEHKPTVTVISTTGLATPAGAKedvpFGLqTLYHLLAEPHKDKKRMEEIISEkenAALFq 198
                     444555555666666677799999999873333222333456777777765432221111122212245778888**********8843323324 PP

                     .EEEEEE-CE.......E-ST--SEEEEETTSS----EEEHHHHHHHHHH CS
  NAD_binding_10 138 .wTivrpggL.......tdepttkyrvvekgepfkggsisradVAdvlva 179
                       +i rp+ L        d+ ++++r+++++ p +g+si+r dV +++ +
      EEA22520.1 199 gVVITRPTLLygdgivmVDGVQKTVRAGTEDAPARGYSIARTDVGNWIWQ 248
                     579999999743333224455788999999***************99976 PP

>> HTH_24  Winged helix-turn-helix DNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   3.4e-05      0.15       4      29 ..      36      61 ..      33      64 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 3.4e-05
      HTH_24  4 tdrkILelLqknprisqreLAerlgl 29
                t  k++  L+k+p+i+ + LAerl++
  EEA22520.1 36 TPQKLIDSLKKQPGITDAVLAERLHI 61
                5679999*****************98 PP

>> CinA  Competence-damaged protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   4.9e-05      0.22      49     115 ..      98     168 ..      89     195 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 4.9e-05
        CinA  49 vtYsneaKeelLgvseetleehgavSeevaeem....aegarerlgadiavavtGiAGpsggteekpvGtv 115
                  +Y ++ K  lL  + +  +     + + +++m    ae+  e+  +   +++tG A p g++e+ p G+ 
  EEA22520.1  98 GAYPQRKKGTLLTFEMDNPKITEQSTTALVSAMreihAEQHPEHKPTVTVISTTGLATPAGAKEDVPFGLQ 168
                 566677777777766666666666666666666333355556666677889******************74 PP

>> CcmH  Cytochrome C biogenesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   7.7e-05      0.34      46      85 ..      61     100 ..      57     141 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 7.7e-05
                 TTT--SHHHHHHHHHHHHHHHHT--HHHHHHHHHHHHTTT CS
        CcmH  46 iadSnaelAkdlrrevremlkaGksdeeivdylvarYGdf 85 
                 i   +a++A+d++r +  + ++Gk++++ vd +v+  G +
  EEA22520.1  61 IVKGDATVAADVKRTLLFQADDGKTESKLVDAIVSGIGAY 100
                 77889*****************************999976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (269 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       408  (0.0227564); expected 358.6 (0.02)
Passed bias filter:                      371  (0.0206927); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.42u 0.27s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2014.01
//
Query:       EEA22521.1  [L=1133]
Description: sister chromatid cohesion factor (Chl12), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.5e-12   46.0   0.0    1.5e-11   44.8   0.0    1.6  1  AAA       ATPase family associated with various cellular acti
    1.8e-05   25.0   0.0    4.1e-05   23.9   0.0    1.5  1  AAA_22    AAA domain
    0.00018   21.3   0.0    0.00039   20.2   0.0    1.5  1  RuvB_N    Holliday junction DNA helicase RuvB P-loop domain
    0.00029   21.0   0.1     0.0013   18.9   0.0    2.2  2  AAA_33    AAA domain
     0.0007   19.6   0.0     0.0015   18.6   0.0    1.5  1  AAA_5     AAA domain (dynein-related subfamily)
    0.00078   19.4   0.0     0.0025   17.8   0.0    1.8  1  Rad17     Rad17 P-loop domain
     0.0029   17.6   0.0     0.0061   16.6   0.0    1.5  1  AAA_14    AAA domain
     0.0048   17.3   0.0      0.026   14.9   0.0    2.1  2  AAA_16    AAA ATPase domain
  ------ inclusion threshold ------
      0.035   14.0   0.0      0.077   12.9   0.0    1.6  1  NTPase_1  NTPase
      0.069   13.4   0.1       0.57   10.4   0.0    2.5  3  AAA_28    AAA domain
        0.1   13.0   0.1       0.41   11.1   0.0    2.1  2  AAA_17    AAA domain


Domain annotation for each model (and alignments):
>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.8   0.0   9.4e-15   1.5e-11       1      91 [.     449     548 ..     449     599 .. 0.84

  Alignments for each domain:
  == domain 1  score: 44.8 bits;  conditional E-value: 9.4e-15
                 EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSS..........STTHHHHHHHHHHHHHHHTS..TSEEEEEETGGGHHHHHTTCCCHHHHHHHH CS
         AAA   1 vllyGppGtGKTllakavakelgvefleisgsellsk..........yvgesekkirelfkeakeka..kpsilfiDEidalaksrsgseseeeervvn 87 
                 ++l+GppG GKT+la+  a+++g e+lei++s+ ++           +  e+ k+i++  ++ k+++  +p+++++DE+d +++      s+ e   ++
  EEA22521.1 449 LMLTGPPGLGKTTLAHVCAQQAGYEVLEINASDERNRdivkgrirdaVGTENVKSISAGTDSTKSSRsgRPVCVVVDEVDGVVGGA---GSGGEGGFIK 544
                 589********************************889******997777889999999999888889999***********9988...4444555555 PP

                 HHHH CS
         AAA  88 qLlt 91 
                 +L+ 
  EEA22521.1 545 ALID 548
                 5554 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.0   2.5e-08   4.1e-05       5     104 ..     446     531 ..     443     559 .. 0.78

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 2.5e-08
      AAA_22   5 agilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelkaerlsseellealeqalraravielliiDEaqhl 103
                 ++il++tG++G GKTtl+   ++q+         + ev++++++ + +++ +  ++  a+g e+ +   s ++  +  ++ +r+ +  +++++DE++ +
  EEA22521.1 446 RKILMLTGPPGLGKTTLAHVCAQQA---------GYEVLEINASDERNRDIVKGRIRDAVGTENVK---SISAG-TDSTKSSRSGRP-VCVVVDEVDGV 530
                 789*********************9.........*************99999*********88888...33333.444444444444.8*******986 PP

      AAA_22 104 r 104
                  
  EEA22521.1 531 V 531
                 4 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.0   2.4e-07   0.00039      36      61 ..     449     474 ..     439     489 .. 0.83

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 2.4e-07
      RuvB_N  36 vllyGpPGlGkttlakiiakelgvkl 61 
                 ++l+GpPGlGkttla++ a++ g ++
  EEA22521.1 449 LMLTGPPGLGKTTLAHVCAQQAGYEV 474
                 6899****************998776 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       4.1   6.6e+03      34      74 ..      17      58 ..      15      61 .. 0.77
   2 !   18.9   0.0     8e-07    0.0013       2      33 ..     449     482 ..     448     526 .. 0.71

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 4.1
      AAA_33 34 rrrlfgtdqqsktdytrvldrlyqilnelarkalsagrn.vi 74
                ++ + +t  qs+ ++t ++d++ + +++++++a + +rn v+
  EEA22521.1 17 HSEVSNTLLQSEPELTSFSDDIEALQQRRLEIAEENRRNgVV 58
                667788888899999999999999999999988887777344 PP

  == domain 2  score: 18.9 bits;  conditional E-value: 8e-07
      AAA_33   2 vllvGlpGsGKstlaerllkklgavllssdt..l 33 
                 ++l G+pG GK+tla+  +++ g+++l+ ++  +
  EEA22521.1 449 LMLTGPPGLGKTTLAHVCAQQAGYEVLEINAsdE 482
                 7999**********************87665442 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.0   8.9e-07    0.0015       2      74 ..     449     527 ..     448     530 .. 0.73

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 8.9e-07
                 EEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--.........--------......G-SEEEEESG CS
       AAA_5   2 vlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreikngttslvdsplvraar......egeilvlDEv 74 
                 ++L GppG gK++la   a+  + ev++++ ++  +++ +kgr++ + gt+  +  ++ +  +      ++  +v+DEv
  EEA22521.1 449 LMLTGPPGLGKTTLAHVCAQQAGYEVLEINASDERNRDIVKGRIRDAVGTENVKSISAGTDSTkssrsgRPVCVVVDEV 527
                 79***********************************999999995544433333333332224555555555666666 PP

>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   1.5e-06    0.0025      42      79 ..     443     479 ..     385     505 .. 0.79

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 1.5e-06
       Rad17  42 srkkriLLisGPsGCgkstvvkvLskelgiklrewlnp 79 
                  ++++iL+++GP+G gk+t  +v +++ g+++ e  n+
  EEA22521.1 443 FAPRKILMLTGPPGLGKTTLAHVCAQQAGYEVLEI-NA 479
                 46778**************************9874.44 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   3.7e-06    0.0061       2      74 ..     446     528 ..     445     556 .. 0.72

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 3.7e-06
      AAA_14   2 rkilvitGaRrvGKTtllkqlikellvkkesilyinldderdkkladpe.......kllelileklke..........ekktylflDEiq 74 
                 rkil++tG+   GKTtl++ ++++      ++l+in  der++++ + +       ++ + i     +           +  +++ DE+ 
  EEA22521.1 446 RKILMLTGPPGLGKTTLAHVCAQQAG---YEVLEINASDERNRDIVKGRirdavgtENVKSIS----AgtdstkssrsGRPVCVVVDEVD 528
                 69*******************99998...9************665433222222222223333....12233455665667778888886 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   1.6e-05     0.026      25      58 ..     447     479 ..     438     516 .. 0.77
   2 ?   -2.5   0.0       3.7     6e+03     131     145 ..     514     528 ..     511     536 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.6e-05
      AAA_16  25 elvllsGesGvGKsslvrellralekdggiflrg 58 
                  +++l+G++G GK++l+  +++++  + ++ +++
  EEA22521.1 447 KILMLTGPPGLGKTTLAHVCAQQAGYE-VLEINA 479
                 799******************999888.333333 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 3.7
      AAA_16 131 srderplvlvlDdlq 145
                 sr +rp+ +v+D+++
  EEA22521.1 514 SRSGRPVCVVVDEVD 528
                 67799*******998 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   4.7e-05     0.077       2      29 ..     449     473 ..     448     528 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 4.7e-05
                 EEEE--TTSSHHHHHHHHHHHH...GGG CS
    NTPase_1   2 vfiTGppGvGKtTlvkkvlellkssgvk 29 
                 +++TGppG GKtTl +  +++    g++
  EEA22521.1 449 LMLTGPPGLGKTTLAHVCAQQA---GYE 473
                 589************9888766...555 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0       1.4   2.4e+03      46      77 ..      31      66 ..      16      69 .. 0.63
   2 ?   10.4   0.0   0.00035      0.57       3      27 ..     450     475 ..     448     502 .. 0.78
   3 ?   -3.8   0.0       8.4   1.4e+04      74      95 ..     991    1012 ..     988    1023 .. 0.64

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 1.4
      AAA_28 46 lpwv.edllafaervleeqleeeaaa...aankvlf 77
                l +  +d+ a+++r+le + e+ ++    +++ + +
  EEA22521.1 31 LTSFsDDIEALQQRRLEIAEENRRNGvviQSRSWKL 66
                444447899999999988877666555555655555 PP

  == domain 2  score: 10.4 bits;  conditional E-value: 0.00035
      AAA_28   3 vitGgestGKTtlleaLaar.gypvv 27 
                 ++tG+++ GKTtl+   a++ gy+v+
  EEA22521.1 450 MLTGPPGLGKTTLAHVCAQQaGYEVL 475
                 69***************988888876 PP

  == domain 3  score: -3.8 bits;  conditional E-value: 8.4
      AAA_28   74 kvlfcDrglldtlaYaraygge 95  
                  k +++D+g+ +++ Ya +   +
  EEA22521.1  991 KGTILDTGSSAPVRYAIRQVLD 1012
                  6678899999998888444333 PP

>> AAA_17  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.1       7.4   1.2e+04     107     127 ..      33      53 ..      30      59 .. 0.73
   2 ?   11.1   0.0   0.00025      0.41       1      25 [.     452     476 ..     452     495 .. 0.90

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 7.4
                 EEE--HHHHHHHHHHHTTST- CS
      AAA_17 107 lleadpeeilerrlkdrtrgr 127
                  +++d e + +rrl+  +++r
  EEA22521.1  33 SFSDDIEALQQRRLEIAEENR 53 
                 577888899999988755544 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00025
                 EE-TTSSHHHHHHHHHHHHTEEEEE CS
      AAA_17   1 lGgPGsGKgtqceklvekygfthls 25 
                 +G+PG GK+t++   +++ g+++l+
  EEA22521.1 452 TGPPGLGKTTLAHVCAQQAGYEVLE 476
                 7*********************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1133 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       484  (0.0269954); expected 358.6 (0.02)
Passed bias filter:                      387  (0.0215851); expected 358.6 (0.02)
Passed Vit filter:                        74  (0.00412739); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.81u 0.29s 00:00:01.10 Elapsed: 00:00:00.46
# Mc/sec: 7439.46
//
Query:       EEA22522.1  [L=700]
Description: RSC complex subunit (RSC8), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-32  111.7   0.1    3.8e-32  110.5   0.1    1.7  1  SWIRM            SWIRM domain
      6e-31  106.2   9.5    1.3e-30  105.2   9.5    1.6  1  SWIRM-assoc_1    SWIRM-associated region 1
    7.9e-09   35.6   0.1    2.8e-08   33.8   0.0    1.9  2  Myb_DNA-binding  Myb-like DNA-binding domain
    2.3e-06   27.8   0.2    7.1e-06   26.2   0.2    1.8  1  Myb_DNA-bind_6   Myb-like DNA-binding domain
  ------ inclusion threshold ------
      0.067   13.4   0.4       0.19   11.9   0.4    1.8  1  SANT_DAMP1_like  SANT/Myb-like domain of DAMP1
       0.12   12.2   0.1       0.12   12.2   0.1    2.7  3  Myb_DNA-bind_7   Myb DNA-binding like
        2.1    8.2   4.3         14    5.6   4.3    2.1  1  ZZ               Zinc finger, ZZ type


Domain annotation for each model (and alignments):
>> SWIRM  SWIRM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.5   0.1   1.5e-35   3.8e-32       1      89 []     130     215 ..     130     215 .. 0.97

  Alignments for each domain:
  == domain 1  score: 110.5 bits;  conditional E-value: 1.5e-35
       SWIRM   1 ps.sewFdpdslhpiEkellselfngk..dktpeeYlkiRnkiialyrenpkeyltvteaqkalkrrrltgidvnllsrihefLerwGlINf 89 
                 ps s+wFd++++hpiEk++++e+fng+  +ktp++Y+++R+++i++yr np eyltvt++     rr+l+g dv++++r+h+fLe+wGlIN+
  EEA22522.1 130 PSySSWFDMHQIHPIEKKAMQEFFNGRnrSKTPAVYKDYRDFMINTYRLNPIEYLTVTAC-----RRNLAG-DVCAIMRVHSFLEQWGLINY 215
                 67799*******************999989******************************.....******.*******************8 PP

>> SWIRM-assoc_1  SWIRM-associated region 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  105.2   9.5     5e-34   1.3e-30       1      83 [.     561     643 ..     561     644 .. 0.98

  Alignments for each domain:
  == domain 1  score: 105.2 bits;  conditional E-value: 5e-34
  SWIRM-assoc_1   1 siALaaaAakAkvlasqeereiqrlvaqlvetqlkKlelKLkqfeelEklleaerrelekqrqqLlleRlalkkevlkvaekl 83 
                    +iALaa+Aa+A +las+eere++rlv+++v+++l+K+e+KL+qf+e+E+++eaerrele  rqqL+ +Rla+kk+v++v++++
     EEA22522.1 561 TIALAASAARAGALASHEEREMTRLVSAAVNVTLQKFEIKLAQFNEMEEIIEAERRELELTRQQLFADRLAFKKRVKDVQDAF 643
                    59*****************************************************************************9986 PP

>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.8   0.0   1.1e-11   2.8e-08       4      45 ..     406     447 ..     404     448 .. 0.97
   2 ?   -1.9   0.0       1.6   4.1e+03      26      40 ..     496     510 ..     495     515 .. 0.81

  Alignments for each domain:
  == domain 1  score: 33.8 bits;  conditional E-value: 1.1e-11
                      SBHHHHHHHHHHHHHHTTCHHHHHHHHTSS-HHHHHHHHHHH CS
  Myb_DNA-binding   4 WteeEdelLleavkkhGnrWkkIaerlggRtekqcrsrwrny 45 
                      W+  E  lLle+++ + ++W  Ia+++g+Rt+++c  +++++
       EEA22522.1 406 WSDSELILLLEGIETFDEDWQQIADHVGTRTREECVMKFLQL 447
                      ***************************************986 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 1.6
                      HHHHHTSS-HHHHHH CS
  Myb_DNA-binding  26 IaerlggRtekqcrs 40 
                      +a    gR+ +q+r 
       EEA22522.1 496 VAAAAAGRSVEQIRK 510
                      6777789******96 PP

>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.2   0.2   2.8e-09   7.1e-06       1      43 [.     406     447 ..     406     464 .. 0.90

  Alignments for each domain:
  == domain 1  score: 26.2 bits;  conditional E-value: 2.8e-09
  Myb_DNA-bind_6   1 WteeEdeiLlklvekygndWknIaealnrRtpkqcfdrwknkL 43 
                     W++ E  +Ll++ e++  dW +Ia++ + Rt ++c +++++ L
      EEA22522.1 406 WSDSELILLLEGIETFDEDWQQIADHVGTRTREECVMKFLQ-L 447
                     9**************************99**********99.6 PP

>> SANT_DAMP1_like  SANT/Myb-like domain of DAMP1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.4   7.5e-05      0.19      11      60 ..     387     437 ..     382     459 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 7.5e-05
  SANT_DAMP1_like  11 evpeytdeeYeellkeed.WtkeetdyLfdlckeydlrfvviaDryelekk 60 
                      + ++ ++ +Y++   ++  W+ +e   L++ ++++d  +  iaD+  ++++
       EEA22522.1 387 DFVRLEETDYTQNKDKDAgWSDSELILLLEGIETFDEDWQQIADHVGTRTR 437
                      5677888899888766445*************************9877654 PP

>> Myb_DNA-bind_7  Myb DNA-binding like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0       2.4   6.2e+03      32      44 ..     148     160 ..     147     166 .. 0.81
   2 ?   12.2   0.1   4.8e-05      0.12       4      51 ..     399     446 ..     395     470 .. 0.85
   3 ?   -0.3   0.7      0.39   9.9e+02      51      85 ..     577     614 ..     576     617 .. 0.67

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 2.4
  Myb_DNA-bind_7  32 liaklfpkrtrrq 44 
                      ++++f++r+r++
      EEA22522.1 148 AMQEFFNGRNRSK 160
                     6999*****9986 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 4.8e-05
  Myb_DNA-bind_7   4 krkktkkWskeetekFYkaLsqfGtDFsliaklfpkrtrrqlKlKFkk 51 
                     ++ k   Ws++e  +  +++++f  D++ ia     rtr++  +KF +
      EEA22522.1 399 NKDKDAGWSDSELILLLEGIETFDEDWQQIADHVGTRTREECVMKFLQ 446
                     4458999**************************************965 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.39
  Myb_DNA-bind_7  51 kEerknpeliekalkkrke...ldleefkeeaekekee 85 
                     +Eer+  +l+++a++   +   ++l++f+e+ e ++ e
      EEA22522.1 577 HEEREMTRLVSAAVNVTLQkfeIKLAQFNEMEEIIEAE 614
                     69*********996654443126666777777666555 PP

>> ZZ  Zinc finger, ZZ type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   4.3    0.0054        14      26      43 ..     365     383 ..     331     385 .. 0.74

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0054
                 SS-EE-HHHHHH..H---S CS
          ZZ  26 sdYDLCqsCfst.hkagkh 43 
                 + YD+C +Cf + +  + h
  EEA22522.1 365 RKYDICPNCFLEaRLPASH 383
                 56********998876666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (700 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       771  (0.043003); expected 358.6 (0.02)
Passed bias filter:                      394  (0.0219756); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.59u 0.30s 00:00:00.88 Elapsed: 00:00:00.42
# Mc/sec: 5046.04
//
Query:       EEA22523.1  [L=606]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.027   14.4   0.3       0.12   12.3   0.0    2.2  2  Myb_DNA-bind_7   Myb DNA-binding like
      0.038   14.0   0.6       0.13   12.3   0.0    2.1  2  Phage_lysozyme2  Phage tail lysozyme


Domain annotation for each model (and alignments):
>> Myb_DNA-bind_7  Myb DNA-binding like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   1.3e-05      0.12      10      65 ..     131     189 ..     126     212 .. 0.82
   2 ?   -3.0   0.4      0.76   6.8e+03      50      65 ..     544     559 ..     524     567 .. 0.70

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.3e-05
  Myb_DNA-bind_7  10 kWskeetekFYkaLsqfGt.DFsliaklfpkrtrrql..KlKFkkEerknpeliekalk 65 
                     +W+ +e++ F+ aL   G  +   ia+l ++++r ++  + KF +E  ++ +l+e +l 
      EEA22523.1 131 QWTGKENDAFFTALARKGKgNVGEIARLINSKSRLEVadYIKFLEERLQRHQLLEPSLL 189
                     8*****************75899**************55579*9999999998887754 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 0.76
  Myb_DNA-bind_7  50 kkEerknpeliekalk 65 
                     +kE++k+p +i++ ++
      EEA22523.1 544 NKEKQKEPPNITDEMR 559
                     5677777777666555 PP

>> Phage_lysozyme2  Phage tail lysozyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   1.4e-05      0.13      36      72 ..     114     151 ..     106     187 .. 0.79
   2 ?   -2.1   0.2      0.38   3.4e+03      93     130 ..     511     548 ..     489     552 .. 0.66

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.4e-05
  Phage_lysozyme2  36 gavesalskggggyGlvQWtgsrrtallkyakakgk.n 72 
                      ++++++++ +   +GlvQWtg++++a+  ++++kgk n
       EEA22523.1 114 KTWNKQQNVTLATVGLVQWTGKENDAFFTALARKGKgN 151
                      6677777889999*************999999998873 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.38
  Phage_lysozyme2  93 ssektakkalksatsveeaakaflksferpgdesakle 130
                       ++++  +   s+++ + + +   + fe pg+++++++
       EEA22523.1 511 DDYNAYLDRQASHKEEARLRELLNCTFEHPGKKNKEKQ 548
                      44666666667777777788888899999999954443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (606 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1557  (0.0868425); expected 358.6 (0.02)
Passed bias filter:                      486  (0.0271069); expected 358.6 (0.02)
Passed Vit filter:                        64  (0.00356964); expected 17.9 (0.001)
Passed Fwd filter:                        22  (0.00122706); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.80u 0.27s 00:00:01.07 Elapsed: 00:00:00.43
# Mc/sec: 4229.48
//
Query:       EEA22524.1  [L=666]
Description: DEAD/DEAH box helicase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.4e-26   91.6   0.4      4e-25   88.8   0.0    2.6  4  ResIII      Type III restriction enzyme, res subunit
    6.1e-16   58.7   0.0    5.4e-15   55.7   0.0    2.5  2  Helicase_C  Helicase conserved C-terminal domain
    6.5e-11   42.3   0.0      6e-10   39.2   0.0    2.4  2  DEAD        DEAD/DEAH box helicase
    9.7e-05   22.1   0.1    0.00034   20.4   0.0    2.0  2  SWI2_SNF2   SWI2/SNF2 ATPase
     0.0049   16.1   0.0      0.012   14.9   0.0    1.6  1  DUF2075     Uncharacterized conserved protein (DUF2075)


Domain annotation for each model (and alignments):
>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.8   0.0   1.1e-28     4e-25       1     170 [.      58     220 ..      58     221 .. 0.90
   2 ?   -1.8   0.0      0.77   2.8e+03      51      84 ..     300     333 ..     294     358 .. 0.69
   3 ?   -3.3   0.0       2.2   7.8e+03     100     118 ..     463     481 ..     428     491 .. 0.61
   4 ?   -1.9   0.3      0.78   2.8e+03     104     125 ..     620     639 ..     565     655 .. 0.51

  Alignments for each domain:
  == domain 1  score: 88.8 bits;  conditional E-value: 1.1e-28
                 --EE-HHHHHHHHHHT......TTSEEEEEESTTSTHHHHHHHHHHHH-S......-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--.. CS
      ResIII   1 klelreyQeeaienlleklkskrdkrglikmaTGtGKTlvaaklierllkkgkee.kflflvprkslleqtleefkkflseaykeigkkvsgdkkkake 98 
                 k++lr+yQee i++++e+l  k+++r+ + +aTG+GKT++ ++li r+   +++  ++l++++rk+l+eq+ ++ +  +++++    ++  g +k +  
  EEA22524.1  58 KIQLRDYQEESIQSVIENLG-KGHNRLGLSLATGSGKTVIFTQLIHRIPPRNGRAdQTLIIAHRKELVEQAARHCRLAYPDKT---VEIEMGATKAS-- 150
                 589****************9.***************************87665555************************994...45555555555.. PP

                 .....-SEEEEEHHHHHHTH........HHHTTT-SEEEEETGGGTTS.TTTHHHHHT-.......--SEEEEEESS-S CS
      ResIII  99 kdstnkkilvttiqsldadseeeeeeseellrdrfdviiiDEaHrlgakkswreilekf.......keavllglTATpe 170
                      ++i+v++i sl ++        e++++++f+++++DEaH++ a  ++r++le+f       ++  l+g++AT+ 
  EEA22524.1 151 ---GAADITVASIRSLASKG-----RIEKFDPSYFKLVLVDEAHHIVA-PQYRQALEYFgltepsnNAPALVGVSATFF 220
                 ...799************99.....889********************.*********98887766669********86 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.77
                 .....-EEEEESSHHHHHHHHHHGGGGTGG.... CS
      ResIII  51 kgkeekflflvprkslleqtleefkkflseayke 84 
                 + +++ +l+++  ++ + q+ e+f++   +a+  
  EEA22524.1 300 ASDRRSTLVFCVDIEHVRQLTEAFRDNGIDARYI 333
                 4455678888888888999999999888877654 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 2.2
                 ....-SEEEEEHHHHHHTH CS
      ResIII 100 dstnkkilvttiqsldads 118
                  +++ ++++tt++s+   +
  EEA22524.1 463 GDDDVDVTFTTYDSVFDLL 481
                 4566888888888887655 PP

  == domain 4  score: -1.9 bits;  conditional E-value: 0.78
                 -SEEEEEHHHHHHTH....... CS
      ResIII 104 kkilvttiqsldadseeeeees 125
                 +k+ + t ++++++++++  ++
  EEA22524.1 620 TKLRFGTKNRFQSEQKKR--KK 639
                 344444444444444222..11 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0      0.39   1.4e+03      13      29 ..      88     104 ..      80     140 .. 0.73
   2 !   55.7   0.0   1.5e-18   5.4e-15      10     110 ..     297     397 ..     275     398 .. 0.91

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.39
                 TTTTSEEEEEESSHHHH CS
  Helicase_C  13 eeeggkilifvntidrl 29 
                     gk++if++ i r+
  EEA22524.1  88 ATGSGKTVIFTQLIHRI 104
                 56678999999999866 PP

  == domain 2  score: 55.7 bits;  conditional E-value: 1.5e-18
                 HHHTTTTSEEEEEESSHHHHHH.HHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSSHHHHHHHHTTS CS
  Helicase_C  10 lkleeeggkilifvntidrlek.vklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprnvtsyiqriGRt 107
                 l++ ++++ +l+f+  i+++ + ++ + + +gi + ++++++p + r+e le+f+kge+ vL+      +G dip++++V+   + r+ + +iq+iGR 
  EEA22524.1 297 LTHASDRRSTLVFCVDIEHVRQlTEAF-RDNGIDARYITANTPRQTRNEELEAFKKGEYPVLLNCGLFTEGTDIPNIDCVVLARPTRSKSLLIQMIGRG 394
                 46778999**********996555555.4559******************************************************************9 PP

                 SST CS
  Helicase_C 108 gRa 110
                  R 
  EEA22524.1 395 LRL 397
                 985 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.2   0.0   1.7e-13     6e-10       2     171 ..      63     222 ..      62     227 .. 0.77
   2 ?   -0.1   0.0      0.19   6.9e+02      45     116 ..     418     485 ..     401     496 .. 0.62

  Alignments for each domain:
  == domain 1  score: 39.2 bits;  conditional E-value: 1.7e-13
                 HHHHHHHHHHH....TT.CEEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHHH CS
                 xxxxxxxxxxx....xx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   2 diQaeaiplil....gg.gdvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskld 95 
                 d+Q+e+i+ ++    +g + + ++ +TGsGKT +f   + +i    ++ ++ ++li++  +eL+eq +++++      d +v+  +g ++a       +
  EEA22524.1  63 DYQEESIQSVIenlgKGhNRLGLSLATGSGKTVIFTQLIHRIPP--RNGRADQTLIIAHRKELVEQAARHCRLAYP--DKTVEIEMGATKA-------S 150
                 78999999999666644246669***********9988886664..578888*******************76655..5455545554444.......3 PP

                 TTCSEEEEEHHHHHHHHHCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBS.H CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.x RF
        DEAD  96 ngvdivvgtpgrlddllstgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlp.k 171
                   +di+v+    l++  + +k++ s ++++ +DEa+ +   ++++ ++  +  + + +++      ++ +SAT+  +
  EEA22524.1 151 GAADITVASIRSLASKGRIEKFDPSYFKLVLVDEAHHIVAPQYRQALEY-FGLT-EPSNNA---PALVGVSATFFrF 222
                 449***********988899999*****************999999998.4444.222222...2499999998755 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.19
                 STS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEETTSSHHHHHHHH.HTTCSEEEEEHHHHHHHHHCTS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  45 ktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliiggvaardqlskl.dngvdivvgtpgrlddllstgk 116
                  ++p  + + P ++L  q +++++k+k++ d      i        ++ l d +vd++++t + ++dll++++
  EEA22524.1 418 MSTPTLFGLDPDEALNTQSVKDIQKRKEHEDFDPD--IP---DAGYIRPLgDDDVDVTFTTYDSVFDLLNDER 485
                 55666777778888888888888888886443322..22...2222333324457777777777777776554 PP

>> SWI2_SNF2  SWI2/SNF2 ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.0   9.5e-08   0.00034       2     138 ..      65     194 ..      64     201 .. 0.79
   2 ?   -3.0   0.2       1.3   4.7e+03      68      90 ..     629     651 ..     616     657 .. 0.57

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 9.5e-08
   SWI2_SNF2   2 QyravekavervkegdrkgGviWHtqGSGKsltmvflakklleeelknpkvvvvtDRkdLdkQlsktfakageekpkqaesrkeLkellekesekiift 100
                 Q  ++++++e++ +g+++ G+    +GSGK++  + l +++  ++ +  + +++  Rk+L +Q +++ + a  +k++++e +    ++ ++ +++i ++
  EEA22524.1  65 QEESIQSVIENLGKGHNRLGLSL-ATGSGKTVIFTQLIHRIPPRNGRADQTLIIAHRKELVEQAARHCRLAYPDKTVEIEMG---ATK-ASGAADITVA 158
                 66778888999988889999865.67*******9999999999788999999************999997766554444444...223.356899**** PP

   SWI2_SNF2 101 tiqKfeeeekeklevlsereniivlvDEaHRsqygela 138
                  i  ++++   ++e+++ +   +vlvDEaH     +++
  EEA22524.1 159 SIRSLASKG--RIEKFDPSYFKLVLVDEAHHIVAPQYR 194
                 *****7653..58999999999********86655555 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 1.3
   SWI2_SNF2  68 tfakageekpkqaesrkeLkell 90 
                  f++ +++++k+ + rke+++++
  EEA22524.1 629 RFQSEQKKRKKEEKMRKEFEKQI 651
                 44444444444555555555555 PP

>> DUF2075  Uncharacterized conserved protein (DUF2075)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   3.3e-06     0.012      10     102 ..      89     190 ..      88     211 .. 0.62

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 3.3e-06
     DUF2075  10 aGtGKtvvllnllaeleddeeertavylsvNhplvlvlrealakke...........ekkkkkeafeklssfinnlsef......kkaeekkeepkedv 91 
                 +G+GKtv+  +l++++   +++r  + l+  h+  lv + a   ++           ++ +k + +++ +               k ++ek +   +++
  EEA22524.1  89 TGSGKTVIFTQLIHRI-PPRNGRADQTLIIAHRKELVEQAARH-CRlaypdktveieMGATKASGAADITV--A----SirslasKGRIEKFDPSYFKL 179
                 7***************.55555555555555554443332222.222334444443323333333333332..2....12334668999999999**** PP

     DUF2075  92 vivDEAhrllt 102
                 v+vDEAh +  
  EEA22524.1 180 VLVDEAHHIVA 190
                 *******9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (666 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1148  (0.0640303); expected 358.6 (0.02)
Passed bias filter:                      738  (0.0411624); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.68u 0.28s 00:00:00.96 Elapsed: 00:00:00.45
# Mc/sec: 4490.82
//
Query:       EEA22525.1  [L=363]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
     0.0055   16.7   1.2      0.018   15.1   1.2    1.9  1  Complex1_LYR  Complex 1 protein (LYR family)
  ------ inclusion threshold ------
       0.03   14.1   1.6      0.055   13.2   1.6    1.3  1  TAF1D         TATA box-binding protein-associated factor 1D


Domain annotation for each model (and alignments):
>> Complex1_LYR  Complex 1 protein (LYR family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   1.2     2e-06     0.018       5      47 ..      14      58 ..      11      62 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 2e-06
  Complex1_LYR  5 sLYRalLRearkfpdyntreyfrrriRdeFrknkh..vtDpekie 47
                  +L Ra LRe++++pd+  r+y+  ++ ++ rk       D++k e
    EEA22525.1 14 HLLRATLRECSYLPDPVARKYMHKYVLERYRKKSAafTADEQKFE 58
                  77799**************************98776666666655 PP

>> TAF1D  TATA box-binding protein-associated factor 1D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   1.6   6.1e-06     0.055      46     124 ..      31     109 ..      17     122 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 6.1e-06
       TAF1D  46 pkpltLkaiferfkkrkkkkkrkkrkykptgrprgrpkgkkntkssqekkkrlkdkgvqfpfvesengrkplpwkkiLt 124
                  +++  k ++er++k+    ++  +k+++  rp  + +++ n++s + +k+  k+    ++++ + n+  + p+ +iL 
  EEA22525.1  31 ARKYMHKYVLERYRKKSAAFTADEQKFEQARRPSAKHQQRLNAASLERQKNLQKSARNFLSLIRRGNQGYQQPLDRILM 109
                 47888899******999999999**********9999999997766655555555555569999999998889988874 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (363 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       684  (0.0381505); expected 358.6 (0.02)
Passed bias filter:                      406  (0.0226449); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2607.62
//
Query:       EEA22526.1  [L=878]
Description: APSES transcription factor (MbpA), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.9e-12   47.4   2.2    1.2e-09   38.5   0.2    4.0  4  Ank_4         Ankyrin repeats (many copies)
      6e-06   26.8   0.1      0.052   14.2   0.1    2.8  3  Ank_2         Ankyrin repeats (3 copies)
    7.7e-05   22.8   1.0     0.0053   17.2   0.1    3.8  4  Ank_3         Ankyrin repeat
    0.00089   19.1   0.3     0.0054   16.6   0.3    2.2  1  KilA-N        KilA-N domain
     0.0013   19.0   0.5       0.17   12.3   0.2    2.7  2  Ank_5         Ankyrin repeats (many copies)
  ------ inclusion threshold ------
        0.1   12.6   4.6        6.1    6.9   0.1    2.7  2  Spc42p        Spindle pole body component Spc42p
       0.21   11.6   0.6       0.89    9.6   0.1    2.1  2  Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C


Domain annotation for each model (and alignments):
>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.5   0.2   4.8e-13   1.2e-09       2      48 ..     432     478 ..     431     490 .. 0.89
   2 ?    1.6   0.0      0.18   4.5e+02      24      43 ..     491     510 ..     485     526 .. 0.77
   3 ?    3.9   0.0     0.033        85      27      44 ..     570     586 ..     559     592 .. 0.83
   4 ?   -4.0   0.0         7   1.8e+04       9      30 ..     699     720 ..     697     723 .. 0.79

  Alignments for each domain:
  == domain 1  score: 38.5 bits;  conditional E-value: 4.8e-13
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAa.krgnv 48 
                 ++aLh+aa+  rl+l++ L+ekg++i++  n+ Getal++A+  r+n+
  EEA22526.1 432 NSALHWAAMLARLPLLHALVEKGVNIYRL-NAAGETALQKAVgTRNNL 478
                 689*************************9.************655554 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.18
       Ank_4  24 gadinaqdnrsGetalhi.Aa 43 
                 g+ i+++ + sG++ lh+ A+
  EEA22526.1 491 GPTIDMV-DHSGRSILHHiAI 510
                 6669999.******9998566 PP

  == domain 3  score: 3.9 bits;  conditional E-value: 0.033
       Ank_4  27 inaqdnrsGetalhiAak 44 
                 +n + +++G+tal iA +
  EEA22526.1 570 VNLR-DDQGDTALNIAGR 586
                 7999.**********965 PP

  == domain 4  score: -4.0 bits;  conditional E-value: 7
       Ank_4   9 aisgrlelvrlLlekgadinaq 30 
                 + ++ l+++++  + + ++ ++
  EEA22526.1 699 IDQNELDSLKRKASDRSNVSRR 720
                 6688899999999988888887 PP

>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.0   9.3e-05      0.24      18      64 ..     419     476 ..     412     498 .. 0.73
   2 !   14.2   0.1     2e-05     0.052       1      62 [.     435     511 ..     435     526 .. 0.78
   3 !    9.2   0.0    0.0007       1.8      29      81 ..     555     604 ..     518     606 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 9.3e-05
       Ank_2  18 egadpn...k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAars.g 64 
                 +g d++   +   ++aLh+Aa+   l ++ +L+e+      ++  g+t+L+ A+   +
  EEA22526.1 419 SGEDLEiplDeYQNSALHWAAMLARLPLLHALVEKgvniyrLNAAGETALQKAVGTrN 476
                 4555555442566899999999998999999999775565666889999999995533 PP

  == domain 2  score: 14.2 bits;  conditional E-value: 2e-05
       Ank_2   1 LhlAakngnlelvklLl.egadpn..k.ngktaLhyAak.ngnlei..vklLleh.......adndgrtpL.hyAar 62 
                 Lh+Aa+   l+l++ L+ +g+++   +  g+taL+ A+  ++nl+      Lle        +d +gr++L h+A+ 
  EEA22526.1 435 LHWAAMLARLPLLHALVeKGVNIYrlNaAGETALQKAVGtRNNLDYrtFPRLLEIlgptidmVDHSGRSILhHIAIM 511
                 8*****87688******888777665469*********9434555455899998445666788899*****888885 PP

  == domain 3  score: 9.2 bits;  conditional E-value: 0.0007
       Ank_2  29 aLhyAakngnleivklLlehadndgrtpLhyAarsghleivklLlekgadinl 81 
                 +    ++ g   +v+ L++  d++g t+L +A r  +  +v  Lle gad+++
  EEA22526.1 555 PQGEIISLG--RFVSELVNLRDDQGDTALNIAGRARS-VLVPQLLEVGADPQI 604
                 444455566..68999998789**********98776.899999999999976 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.1   2.1e-06    0.0053       1      30 [.     430     458 ..     430     459 .. 0.94
   2 ?   -2.2   0.0         4     1e+04       2      13 ..     464     475 ..     463     495 .. 0.73
   3 ?    0.1   0.1      0.72   1.8e+03       2      12 ..     501     511 ..     500     538 .. 0.77
   4 ?    0.7   0.0      0.47   1.2e+03       2      30 ..     577     603 ..     576     604 .. 0.85

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 2.1e-06
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvn 30 
                 +++++Lh+Aa+ ++l+++++L+e kg++++
  EEA22526.1 430 YQNSALHWAAMLARLPLLHALVE-KGVNIY 458
                 579********************.9**997 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 4
       Ank_3   2 GetpLhlAarsg 13 
                 Get+L  A+   
  EEA22526.1 464 GETALQKAVGTR 475
                 899999998655 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.72
       Ank_3   2 GetpLhlAars 12 
                 G+++Lh+ a  
  EEA22526.1 501 GRSILHHIAIM 511
                 89999955443 PP

  == domain 4  score: 0.7 bits;  conditional E-value: 0.47
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G t+L +A r+ ++  v  Lle  gad+ 
  EEA22526.1 577 GDTALNIAGRARSVL-VPQLLE-VGADPQ 603
                 789999999999996.99****.8*9986 PP

>> KilA-N  KilA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.3   2.1e-06    0.0054       6      92 ..     120     185 ..     115     194 .. 0.73

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 2.1e-06
      KilA-N   6 qeiiirrvkdgyinatkllkaaaedtkriddWlrnkstkelleeleedynisekkksektisenrkakpgrlqGtYvhpdlalavas 92 
                 + + + r++d + nat++lk a+          + k tk l +e++  +             e  ++ +g++qGt+v ++  +++++
  EEA22526.1 120 IAV-MKRRSDSWLNATQILKVAG--------VVKAKRTKTLEKEIAAGEH------------EKVQGGYGKYQGTWVSYQRGVELCR 185
                 444.45558*************5........3566777777777776532............33468899********999988874 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.3   0.2   6.5e-05      0.17      13      56 .]     428     471 ..     426     471 .. 0.96
   2 ?    4.2   0.0     0.023        58      41      56 .]     569     584 ..     564     584 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 6.5e-05
       Ank_5  13 dgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 d++ n++Lh+Aa   +++++  L++ g+++   ++ G+tal+ A
  EEA22526.1 428 DEYQNSALHWAAMLARLPLLHALVEKGVNIYRLNAAGETALQKA 471
                 88999************************************977 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.023
       Ank_5  41 dlnltdsrGltaldlA 56 
                   nl+d++G+tal +A
  EEA22526.1 569 LVNLRDDQGDTALNIA 584
                 469**********998 PP

>> Spc42p  Spindle pole body component Spc42p
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   1.7    0.0066        17       8      70 ..     670     735 ..     668     738 .. 0.83
   2 ?    6.9   0.1    0.0024       6.1      30      53 ..     794     817 ..     782     828 .. 0.84

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0066
      Spc42p   8 KeLnkkldekqeEierLn.vlvgslRaKLiKYteln...kKLedqlenlersssslekktedandyi 70 
                 ++L+  l +kq E ++   ++ +s Ra+ i   el    +K  d+  n++r++++le+ +ed  +++
  EEA22526.1 670 RDLTSDLSKKQAEFDHWHaKIRESARARQIDQNELDslkRKASDR-SNVSRRIKNLENDAEDLVNSL 735
                 69999**********9863788********999864332787777.9***********999877766 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0024
      Spc42p  30 slRaKLiKYtelnkKLedqlenle 53 
                 +l ++L+ Y  lnkK++d+   l+
  EEA22526.1 794 TLESRLEAYQGLNKKINDEISLLK 817
                 7889**************965544 PP

>> Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.1   0.00035      0.89      33     120 ..     651     740 ..     639     748 .. 0.79
   2 ?   -0.8   0.0      0.55   1.4e+03      58      82 ..     834     859 ..     787     868 .. 0.61

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00035
  Baculo_PEP_C  33 laqlatlldaietqLnalsedlksllaeldtrldtlltnLtdalnalqdtlrneLtnln...siltnLlssvtNinstLnnllqalnnldl 120
                    a la++   +e++L+ ++ dl+s l++ ++++d+  +++ ++  a q   +neL++l+   s+ +n    + N+++  + l+++l+++  
    EEA22526.1 651 DATLAQIGSLVEETLGGIDRDLTSDLSKKQAEFDHWHAKIRESARARQ-IDQNELDSLKrkaSDRSNVSRRIKNLENDAEDLVNSLKSYYG 740
                   4778888889999***************************99876655.445666666522267789999999999999999999988755 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.55
  Baculo_PEP_C  58 laeldt.rldtlltnLtdalnalqdt 82 
                    + +++ ++d++++ Lt+ ++ l+d+
    EEA22526.1 834 CTGFTAeQVDEAAEGLTKHIKDLNDN 859
                   33333348888888888888888865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (878 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       790  (0.0440627); expected 358.6 (0.02)
Passed bias filter:                      454  (0.0253221); expected 358.6 (0.02)
Passed Vit filter:                        69  (0.00384851); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.71u 0.31s 00:00:01.02 Elapsed: 00:00:00.48
# Mc/sec: 5538.86
//
Query:       EEA22527.1  [L=333]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (333 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       553  (0.0308439); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2294.93
//
Query:       EEA22528.1  [L=983]
Description: TPR domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.4e-08   32.3   0.2    0.00071   19.8   0.1    3.7  3  TPR_17    Tetratricopeptide repeat
    7.6e-08   31.9   0.4     0.0077   15.9   0.0    2.7  2  TPR_11    TPR repeat
    6.4e-07   28.9   6.3      0.026   14.3   0.7    4.4  4  TPR_1     Tetratricopeptide repeat
    3.1e-05   24.0   2.4    0.00088   19.4   0.4    3.1  2  TPR_9     Tetratricopeptide repeat
    3.6e-05   24.2   6.9      0.017   15.6   0.5    3.8  3  TPR_19    Tetratricopeptide repeat
     0.0002   21.3  15.0       0.12   12.5   0.0    5.5  5  TPR_2     Tetratricopeptide repeat
    0.00061   19.8   4.9        1.8    9.0   1.0    4.3  4  TPR_8     Tetratricopeptide repeat
     0.0013   19.3  17.5       0.03   15.0   0.2    4.2  4  TPR_16    Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.016   16.0   0.5      0.016   16.0   0.5    5.0  5  TPR_14    Tetratricopeptide repeat
      0.064   13.3   4.0        2.5    8.3   0.1    3.8  3  TPR_7     Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       9.4   1.7e+04       3      17 ..     400     414 ..     399     415 .. 0.83
   2 !   19.8   0.1     4e-07   0.00071       1      34 []     635     668 ..     635     668 .. 0.95
   3 !    8.0   0.0    0.0022         4       3      25 ..     671     693 ..     670     702 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 9.4
      TPR_17   3 lkaleldPnnadayn 17 
                 ++++e   nn+ +y+
  EEA22528.1 400 TRVIESGSNNWQVYT 414
                 57899999***9997 PP

  == domain 2  score: 19.8 bits;  conditional E-value: 4e-07
      TPR_17   1 lylkaleldPnnadaynnLAelllknGdlmtArq 34 
                 +y+k+l+++P n  a++ L+ ++l++ ++  A++
  EEA22528.1 635 AYKKSLKINPLNHGAWFALGCVQLNREQWHAAIE 668
                 5***************************999985 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.0022
      TPR_17   3 lkaleldPnnadaynnLAelllk 25 
                 ++ ++l+ ++a+a+ nLA +ll+
  EEA22528.1 671 TRTVQLEQDDAEAWSNLAAALLN 693
                 67778899************996 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.5   0.1   2.4e-05     0.043      10      38 ..     629     657 ..     628     660 .. 0.93
   2 !   15.9   0.0   4.3e-06    0.0077       8      39 ..     661     692 ..     658     694 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.4e-05
      TPR_11  10 yeeAieaYkkAlkldPdnaeayynLGlay 38 
                 ye+A eaYkk lk++P n  a+++LG ++
  EEA22528.1 629 YEKAEEAYKKSLKINPLNHGAWFALGCVQ 657
                 9*************************765 PP

  == domain 2  score: 15.9 bits;  conditional E-value: 4.3e-06
      TPR_11   8 GkyeeAieaYkkAlkldPdnaeayynLGlayy 39 
                  ++ +Aie++ + ++l +d+aea++nL++a++
  EEA22528.1 661 EQWHAAIESFTRTVQLEQDDAEAWSNLAAALL 692
                 6899*************************986 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.1       3.1   5.5e+03       4      28 ..     238     262 ..     235     263 .. 0.77
   2 !   14.3   0.7   1.5e-05     0.026      17      32 ..     629     644 ..     628     646 .. 0.96
   3 !   11.8   0.0   9.3e-05      0.17       3      34 .]     649     680 ..     648     680 .. 0.95
   4 ?    2.6   0.2     0.075   1.3e+02       1      12 [.     681     692 ..     681     694 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 3.1
                 HHHHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_1   4 lynlGnayfklgkydeAleyyekAL 28 
                 l  ++ ++ + g   +A ++ +kA 
  EEA22528.1 238 LLERATIHTHHGLDAKARADLDKAA 262
                 5667888888888889999999995 PP

  == domain 2  score: 14.3 bits;  conditional E-value: 1.5e-05
                 HHHHHHHHHHHHHHST CS
       TPR_1  17 ydeAleyyekALelnP 32 
                 y++A+e+y+k L++nP
  EEA22528.1 629 YEKAEEAYKKSLKINP 644
                 9**************9 PP

  == domain 3  score: 11.8 bits;  conditional E-value: 9.3e-05
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1   3 alynlGnayfklgkydeAleyyekALelnPnn 34 
                 a++ lG + ++ +++  A+e + + ++l+ ++
  EEA22528.1 649 AWFALGCVQLNREQWHAAIESFTRTVQLEQDD 680
                 8**************************99875 PP

  == domain 4  score: 2.6 bits;  conditional E-value: 0.075
                 HHHHHHHHHHHH CS
       TPR_1   1 akalynlGnayf 12 
                 a+a+ nl++a++
  EEA22528.1 681 AEAWSNLAAALL 692
                 89*******997 PP

>> TPR_9  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.1     0.063   1.1e+02      32      59 ..     238     265 ..     233     287 .. 0.90
   2 !   19.4   0.4   4.9e-07   0.00088      10      65 ..     628     683 ..     617     693 .. 0.88

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.063
       TPR_9  32 rrdRGlllaqlGclsaAladLeaylala 59 
                 +++R+ ++ + G  ++A+adL+ +++ +
  EEA22528.1 238 LLERATIHTHHGLDAKARADLDKAAEAS 265
                 579*******************999865 PP

  == domain 2  score: 19.4 bits;  conditional E-value: 4.9e-07
       TPR_9  10 dweralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalapdapda 65 
                  +e+a +++   l ++P  ++ ++  G ++  +++++aA++ + + ++l+ d+++a
  EEA22528.1 628 AYEKAEEAYKKSLKINPLNHGAWFALGCVQLNREQWHAAIESFTRTVQLEQDDAEA 683
                 689********************************************999887765 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.1     0.039        70      25      52 ..     527     554 ..     515     563 .. 0.79
   2 !    6.1   0.1    0.0089        16      13      38 ..     598     624 ..     597     627 .. 0.93
   3 !   15.6   0.5   9.5e-06     0.017       7      67 ..     629     690 ..     628     691 .. 0.91

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.039
      TPR_19  25 aearllLAeallalgqldeAealLdalp 52 
                 +e ++  A ++ a+ + ++A+a++ + +
  EEA22528.1 527 LEMWAEVALCYAATEREEKAKAIVRRQL 554
                 577778899**************98766 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.0089
      TPR_19  13 lleqalqedpk.naearllLAeallal 38 
                 ++e+a++ + + +a+a+  LA+++l++
  EEA22528.1 598 MYERAWEVSGQrYARAQRSLARLYLQA 624
                 89***********************98 PP

  == domain 3  score: 15.6 bits;  conditional E-value: 9.5e-06
      TPR_19   7 yaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpdd.aryasLlAk 67 
                 y+ A +++++ l+ +p n  a+ +L  ++l+  q+ +A++   +  + ++dd +++++L A+
  EEA22528.1 629 YEKAEEAYKKSLKINPLNHGAWFALGCVQLNREQWHAAIESFTRTVQLEQDDaEAWSNLAAA 690
                 899*************************************************5555566665 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.3      0.13   2.3e+02       2      29 ..     236     263 ..     235     265 .. 0.88
   2 ?   -0.4   0.1      0.95   1.7e+03       4      22 ..     530     548 ..     528     552 .. 0.85
   3 !   11.5   0.6   0.00015      0.27      17      34 .]     629     646 ..     628     646 .. 0.93
   4 !   12.5   0.0   6.7e-05      0.12       3      33 ..     649     679 ..     647     680 .. 0.93
   5 ?   -0.1   0.2      0.75   1.4e+03       1      12 [.     681     692 ..     681     693 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.13
       TPR_2   2 ealynlGlayyklgdyeeAleafekAle 29 
                   l +++ ++ + g  ++A+++++kA e
  EEA22528.1 236 AFLLERATIHTHHGLDAKARADLDKAAE 263
                 567889999999**************87 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.95
       TPR_2   4 lynlGlayyklgdyeeAle 22 
                 + + +l+y++  + e+A++
  EEA22528.1 530 WAEVALCYAATEREEKAKA 548
                 777899**********986 PP

  == domain 3  score: 11.5 bits;  conditional E-value: 0.00015
       TPR_2  17 yeeAleafekAleldPnn 34 
                 ye+A+ea++k+l+++P n
  EEA22528.1 629 YEKAEEAYKKSLKINPLN 646
                 9***************65 PP

  == domain 4  score: 12.5 bits;  conditional E-value: 6.7e-05
       TPR_2   3 alynlGlayyklgdyeeAleafekAleldPn 33 
                 a+++lG++ +++ ++  A+e f + ++l+ +
  EEA22528.1 649 AWFALGCVQLNREQWHAAIESFTRTVQLEQD 679
                 8***********************9999876 PP

  == domain 5  score: -0.1 bits;  conditional E-value: 0.75
       TPR_2   1 aealynlGlayy 12 
                 aea+ nl+ a++
  EEA22528.1 681 AEAWSNLAAALL 692
                 89*******997 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0        10   1.8e+04      18      30 ..     252     264 ..     241     265 .. 0.77
   2 ?    4.3   0.2     0.033        59       2      26 ..     528     552 ..     527     555 .. 0.88
   3 !    9.0   1.0   0.00098       1.8      17      32 ..     629     644 ..     628     644 .. 0.97
   4 ?    4.8   0.0     0.023        41       3      33 ..     649     679 ..     647     680 .. 0.89

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 10
                 HHHHHHHHHHHHH CS
       TPR_8  18 eeAkeyyekalel 30 
                  +A + + ka e+
  EEA22528.1 252 AKARADLDKAAEA 264
                 5788888888775 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.033
                 CHHHHHHHHHHHTT-HHHHHHHHHH CS
       TPR_8   2 eayynlgsiylklgdyeeAkeyyek 26 
                 e++   +++y  +++ e+Ak+  ++
  EEA22528.1 528 EMWAEVALCYAATEREEKAKAIVRR 552
                 79999***************98776 PP

  == domain 3  score: 9.0 bits;  conditional E-value: 0.00098
                 HHHHHHHHHHHHHHHH CS
       TPR_8  17 yeeAkeyyekaleldp 32 
                 ye+A+e+y+k l+++p
  EEA22528.1 629 YEKAEEAYKKSLKINP 644
                 8**************9 PP

  == domain 4  score: 4.8 bits;  conditional E-value: 0.023
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAkeyyekaleldpd 33 
                 a++ lg++ l+ ++ ++A+e++ + ++l++d
  EEA22528.1 649 AWFALGCVQLNREQWHAAIESFTRTVQLEQD 679
                 8*********************998887766 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.6   0.3     0.007        12      33      64 ..     234     265 ..     226     268 .. 0.83
   2 ?   -1.8   0.3       2.8   5.1e+03      32      55 ..     525     548 ..     517     556 .. 0.75
   3 !    7.9   1.3    0.0028         5      31      65 ..     608     644 ..     597     647 .. 0.85
   4 !   15.0   0.2   1.7e-05      0.03       2      48 ..     652     695 ..     651     699 .. 0.93

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.007
      TPR_16  33 aaeAllllgdaalrqgrlaeAaalyraalraa 64 
                  a++ll+++ ++ ++g  a+A+a +++a++a+
  EEA22528.1 234 KAAFLLERATIHTHHGLDAKARADLDKAAEAS 265
                 689*******************8888887765 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 2.8
      TPR_16  32 daaeAllllgdaalrqgrlaeAaa 55 
                 ++ e++ + ++++++  r ++A a
  EEA22528.1 525 ERLEMWAEVALCYAATEREEKAKA 548
                 467899999*****9999888755 PP

  == domain 3  score: 7.9 bits;  conditional E-value: 0.0028
      TPR_16  31 PdaaeAllllgdaalrq..grlaeAaalyraalraap 65 
                  + a+A+  l++++l++  + +++A+++y++ l+  p
  EEA22528.1 608 QRYARAQRSLARLYLQAkpPAYEKAEEAYKKSLKINP 644
                 779**************9*************999887 PP

  == domain 4  score: 15.0 bits;  conditional E-value: 1.7e-05
      TPR_16   2 alaraalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrqg 48 
                 al+   l++ ++ +A++ +++++ +     d+aeA+ +l+ a+l  +
  EEA22528.1 652 ALGCVQLNREQWHAAIESFTRTVQLE---QDDAEAWSNLAAALLNVS 695
                 899999********************...**************9765 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.4       1.8   3.3e+03       3      30 ..     237     264 ..     235     276 .. 0.83
   2 ?   -1.4   0.1       3.3     6e+03       2      27 ..     528     553 ..     511     561 .. 0.78
   3 ?   16.0   0.5   8.7e-06     0.016       2      42 ..     612     654 ..     611     654 .. 0.91
   4 ?    6.8   0.4    0.0082        15      12      43 ..     658     689 ..     656     690 .. 0.91
   5 ?   -0.3   0.1       1.5   2.8e+03       3      27 ..     858     882 ..     856     887 .. 0.88

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 1.8
      TPR_14   3 allalaeallalGdpdeAiallrralal 30 
                  ll++a ++ + G  ++A+a l++a ++
  EEA22528.1 237 FLLERATIHTHHGLDAKARADLDKAAEA 264
                 5789999999999999999999999765 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 3.3
      TPR_14   2 eallalaeallalGdpdeAiallrra 27 
                 e++++ a  ++a ++ ++A a+ rr 
  EEA22528.1 528 EMWAEVALCYAATEREEKAKAIVRRQ 553
                 56777777777777777777777775 PP

  == domain 3  score: 16.0 bits;  conditional E-value: 8.7e-06
      TPR_14   2 eallalaeallalG..dpdeAiallrralalaPddaeawllla 42 
                 +a++ la+++l++    +++A++++++ l+ +P +  aw++l+
  EEA22528.1 612 RAQRSLARLYLQAKppAYEKAEEAYKKSLKINPLNHGAWFALG 654
                 78999******995459***********************996 PP

  == domain 4  score: 6.8 bits;  conditional E-value: 0.0082
      TPR_14  12 lalGdpdeAiallrralalaPddaeawlllaq 43 
                 l+++++ +Ai+ + r ++l  ddaeaw  la 
  EEA22528.1 658 LNREQWHAAIESFTRTVQLEQDDAEAWSNLAA 689
                 7899***********************99986 PP

  == domain 5  score: -0.3 bits;  conditional E-value: 1.5
      TPR_14   3 allalaeallalGdpdeAiallrra 27 
                 ++l+ a+++l + +p +A a+ ++a
  EEA22528.1 858 LWLLVAKIELWRHRPSKAFAAHEKA 882
                 79999*************9998887 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.1      0.34   6.2e+02       9      29 ..     511     530 ..     505     548 .. 0.64
   2 ?    2.5   0.0       0.1   1.8e+02      15      27 ..     629     641 ..     628     644 .. 0.89
   3 ?    8.3   0.1    0.0014       2.5       1      32 [.     649     680 ..     649     695 .. 0.85

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.34
       TPR_7   9 ysrlGdyeeAielyeqsLalt 29 
                 +++lG  ++A+++ye+ L+++
  EEA22528.1 511 WVSLGGLRTALDIYER-LEMW 530
                 5566666777777777.4443 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.1
       TPR_7  15 yeeAielyeqsLa 27 
                 ye+A+e y++sL 
  EEA22528.1 629 YEKAEEAYKKSLK 641
                 9*********996 PP

  == domain 3  score: 8.3 bits;  conditional E-value: 0.0014
       TPR_7   1 aLlnLarlysrlGdyeeAielyeqsLaltkdp 32 
                 a+++L+ ++ ++ ++  Aie +++  +l+ d+
  EEA22528.1 649 AWFALGCVQLNREQWHAAIESFTRTVQLEQDD 680
                 789*********************44444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (983 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       808  (0.0450667); expected 358.6 (0.02)
Passed bias filter:                      491  (0.0273858); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.75u 0.23s 00:00:00.98 Elapsed: 00:00:00.41
# Mc/sec: 7174.72
//
Query:       EEA22529.1  [L=67]
Description: hypothetical protein PMAA_091570 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (67 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       258  (0.0143901); expected 358.6 (0.02)
Passed bias filter:                      207  (0.0115455); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.27s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 474.35
//
Query:       EEA22530.1  [L=367]
Description: hypothetical protein PMAA_091580 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
  ------ inclusion threshold ------
      0.013   14.6   0.7      0.028   13.5   0.2    1.7  2  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.2   1.6e-06     0.028     111     174 ..      29      86 ..      16      90 .. 0.86
   2 ?   -1.9   0.0     0.077   1.4e+03      70     100 ..     165     207 ..     144     224 .. 0.57

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 1.6e-06
  Fungal_trans 111 alherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrpp 174
                   + +  ++++++++ + + Lhr+  + +      +++   e+r+Rl  ++   Dk +a+ +Gr +
    EEA22530.1  29 RDCTTFSETMISVIYAMELHRDLHSTS------VPFSLVEARKRLLATTHKSDKNVATLFGRST 86 
                   3445599********************......****************************986 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.077
  Fungal_trans  70 iafplraeili............hedfsspssslwilqsLlll 100
                   ++ ++r+++++            +++f s++++ +i+ +L +l
    EEA22530.1 165 VQLFVRHSAVSllvtevhrytisNPPFPSSTPRSEIIRTLSYL 207
                   3334455555555555555555555666666666666655554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (367 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       369  (0.0205812); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.67u 0.31s 00:00:00.98 Elapsed: 00:00:00.55
# Mc/sec: 1998.69
//
Query:       EEA22531.1  [L=477]
Description: ribose phosphate diphosphokinase Prs1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      3e-43  146.5   0.0    3.2e-41  139.9   0.0    2.4  2  Pribosyltran_N  N-terminal domain of ribose phosphate pyropho
    5.6e-35  121.0   0.2      3e-29  102.4   0.1    2.3  2  Pribosyl_synth  Phosphoribosyl synthetase-associated domain
    1.1e-07   31.5   0.1    5.5e-05   22.7   0.1    2.4  2  Pribosyltran    Phosphoribosyl transferase domain


Domain annotation for each model (and alignments):
>> Pribosyltran_N  N-terminal domain of ribose phosphate pyrophosphokinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.9   0.0   5.3e-45   3.2e-41       2     116 .]       5     120 ..       4     120 .. 0.98
   2 !    4.1   0.0    0.0072        43      33      59 ..     356     382 ..     349     412 .. 0.78

  Alignments for each domain:
  == domain 1  score: 139.9 bits;  conditional E-value: 5.3e-45
  Pribosyltran_N   2 kifagssskeLaekiakrlgvelgkakvsrfadgEikveieesvrgkdvfiiqslskpvndnlmelllmidalrrasakritaViPylgysrqdr 96 
                     +if+g+s+++L ++i++rlg   + a++++f++gE+ v+i  svr++dv+i+qs s+++nd+lmell+m++a++ +sak+itaV+Py++ysrq++
      EEA22531.1   5 QIFSGTSHPALTDSICERLGAVPAPAELRKFSNGETLVNIGVSVRNQDVYIVQSGSSKINDSLMELLIMVSACKGGSAKTITAVMPYFPYSRQSK 99 
                     7********************************************************************************************** PP

  Pribosyltran_N  97 k.ksrepisaklvaklLeaaG 116
                     k ++r +i+a+++a+lL+ aG
      EEA22531.1 100 KkSHRGAITARMIANLLNIAG 120
                     *677*************9888 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.0072
  Pribosyltran_N  33 adgEikveieesvrgkdvfiiqslskp 59 
                     +++E  +++  +v++k vfii ++ + 
      EEA22531.1 356 NNDEKTITLVGNVKDKAVFIIDDMIDR 382
                     689999***************998755 PP

>> Pribosyl_synth  Phosphoribosyl synthetase-associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   1.1e-06    0.0064       2      43 ..     162     203 ..     161     217 .. 0.89
   2 !  102.4   0.1     5e-33     3e-29      65     183 ..     351     473 ..     317     474 .. 0.85

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 1.1e-06
                     GGGEEEEESSGGGHHHHHHHHHHTT-EEEEE----------- CS
  Pribosyl_synth   2 yrnavivakspgsakkatsyaerlrlglavihGeqkeaeade 43 
                     +r+av+v+k+ g +k+ ts a+ l+l   ++  e+++ ++++
      EEA22531.1 162 WRDAVVVSKNAGGTKRVTSLADTLKLNFGIVTTERRRPKVHM 203
                     699*****************************9998766554 PP

  == domain 2  score: 102.4 bits;  conditional E-value: 5e-33
                     ---.---------EES--TTSEEEEEEEEE-S-HHHHHHHHHHHHT.T--EEEEEEEEE---TTHHHHHHHS.S--EEEEESSS--HHHHHT.-T CS
  Pribosyl_synth  65 pel.lakekppltvvGdvgGriaiivddliddvesfvaaaevlker.GaykiyvlathGllssdaprllees.aidevvvtntipheiqklr.cs 155
                     p++ +  +   +t+vG+v+ +   i+dd+id   s++ aae++  r Ga  +y +athGl+ ++  +++e+s  id++vvtn+ p   +k+r ++
      EEA22531.1 351 PAMaTNNDEKTITLVGNVKDKAVFIIDDMIDRSGSWITAAETVVRRgGAKTVYCIATHGLFGNNCLEEMENSdVIDHIVVTNSFPIPAEKMRlSK 445
                     44413455678*****************************977666157779******************99458***************99345 PP

                     TEEEE--HHHHHHHHHHHHHT---TT-S CS
  Pribosyl_synth 156 kiktvdislllaeairrihngesmsylf 183
                     k+  +d+s ll+e+irr h+ges+s lf
      EEA22531.1 446 KLTVIDVSALLSESIRRHHYGESISALF 473
                     78889**********************9 PP

>> Pribosyltran  Phosphoribosyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.3   0.0     0.001       6.2      21      75 ..     154     209 ..     142     232 .. 0.83
   2 !   22.7   0.1   9.2e-09   5.5e-05      60     132 ..     343     419 ..     319     439 .. 0.72

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.001
                   EEEEE.--GGGEEEEEEETTTHHHHHHHHHHSTT-EE-EEEEEE-TTT--EE.... CS
  Pribosyltran  21 eilee.yngkpdvvvgiargGvpfakiladeLevplayvrkvkyrpdgseeaargs 75 
                   +i+++   ++  vvv    gG  +++ lad L++ + +v  +++rp++  +++ ++
    EEA22531.1 154 WIRMNvPSWRDAVVVSKNAGGTKRVTSLADTLKLNFGIVTTERRRPKVHMSMTDSM 209
                   4444444478889*********************************9998887765 PP

  == domain 2  score: 22.7 bits;  conditional E-value: 9.2e-09
                   EEEE-TTT--EE.........EE----TTSEEEEE-SEESSSHHHHHHHH.HHHCC-BSEEEEEEEE...E-HHHHHH CS
  Pribosyltran  60 kvkyrpdgseeaargssdes.rlledpagkkVliVDDildtGgTllaale.lLkekgpeevriavlv...dkpateee 132
                   +++ ++d  + +a+++ + + +l +++++k V+i+DD++d  g+ + a+e  +++ g++ v +++ +    +++ ee 
    EEA22531.1 343 VES-DDDEPPAMATNNDEKTiTLVGNVKDKAVFIIDDMIDRSGSWITAAEtVVRRGGAKTVYCIATHglfGNNCLEEM 419
                   344.444444444443333369*******************999999999999******8888877655344444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (477 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       423  (0.0235931); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.74u 0.35s 00:00:01.08 Elapsed: 00:00:00.60
# Mc/sec: 2386.66
//
Query:       EEA22532.1  [L=476]
Description: ribose phosphate diphosphokinase Prs1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      3e-43  146.4   0.0    3.2e-41  139.9   0.0    2.4  2  Pribosyltran_N  N-terminal domain of ribose phosphate pyropho
    3.8e-32  111.8   0.2    2.2e-26   93.1   0.2    2.3  2  Pribosyl_synth  Phosphoribosyl synthetase-associated domain
    1.1e-07   31.5   0.1    5.5e-05   22.7   0.1    2.4  2  Pribosyltran    Phosphoribosyl transferase domain


Domain annotation for each model (and alignments):
>> Pribosyltran_N  N-terminal domain of ribose phosphate pyrophosphokinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.9   0.0   5.3e-45   3.2e-41       2     116 .]       5     120 ..       4     120 .. 0.98
   2 !    4.1   0.0    0.0073        44      33      59 ..     356     382 ..     349     410 .. 0.78

  Alignments for each domain:
  == domain 1  score: 139.9 bits;  conditional E-value: 5.3e-45
  Pribosyltran_N   2 kifagssskeLaekiakrlgvelgkakvsrfadgEikveieesvrgkdvfiiqslskpvndnlmelllmidalrrasakritaViPylgysrqdr 96 
                     +if+g+s+++L ++i++rlg   + a++++f++gE+ v+i  svr++dv+i+qs s+++nd+lmell+m++a++ +sak+itaV+Py++ysrq++
      EEA22532.1   5 QIFSGTSHPALTDSICERLGAVPAPAELRKFSNGETLVNIGVSVRNQDVYIVQSGSSKINDSLMELLIMVSACKGGSAKTITAVMPYFPYSRQSK 99 
                     7********************************************************************************************** PP

  Pribosyltran_N  97 k.ksrepisaklvaklLeaaG 116
                     k ++r +i+a+++a+lL+ aG
      EEA22532.1 100 KkSHRGAITARMIANLLNIAG 120
                     *677*************9888 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.0073
  Pribosyltran_N  33 adgEikveieesvrgkdvfiiqslskp 59 
                     +++E  +++  +v++k vfii ++ + 
      EEA22532.1 356 NNDEKTITLVGNVKDKAVFIIDDMIDR 382
                     689999***************998755 PP

>> Pribosyl_synth  Phosphoribosyl synthetase-associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   1.1e-06    0.0064       2      43 ..     162     203 ..     161     217 .. 0.89
   2 !   93.1   0.2   3.6e-30   2.2e-26      65     178 ..     351     468 ..     317     472 .. 0.84

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 1.1e-06
                     GGGEEEEESSGGGHHHHHHHHHHTT-EEEEE----------- CS
  Pribosyl_synth   2 yrnavivakspgsakkatsyaerlrlglavihGeqkeaeade 43 
                     +r+av+v+k+ g +k+ ts a+ l+l   ++  e+++ ++++
      EEA22532.1 162 WRDAVVVSKNAGGTKRVTSLADTLKLNFGIVTTERRRPKVHM 203
                     699*****************************9998766554 PP

  == domain 2  score: 93.1 bits;  conditional E-value: 3.6e-30
                     ---.---------EES--TTSEEEEEEEEE-S-HHHHHHHHHHHHT.T--EEEEEEEEE---TTHHHHHHHS.S--EEEEESSS--HHHHHT.-T CS
  Pribosyl_synth  65 pel.lakekppltvvGdvgGriaiivddliddvesfvaaaevlker.GaykiyvlathGllssdaprllees.aidevvvtntipheiqklr.cs 155
                     p++ +  +   +t+vG+v+ +   i+dd+id   s++ aae++  r Ga  +y +athGl+ ++  +++e+s  id++vvtn+ p   +k+r ++
      EEA22532.1 351 PAMaTNNDEKTITLVGNVKDKAVFIIDDMIDRSGSWITAAETVVRRgGAKTVYCIATHGLFGNNCLEEMENSdVIDHIVVTNSFPIPAEKMRlSK 445
                     44413455678*****************************977666157779******************99458***************99345 PP

                     TEEEE--HHHHHHHHHHHHHT-- CS
  Pribosyl_synth 156 kiktvdislllaeairrihnges 178
                     k+  +d+s ll+e+irr h+ge 
      EEA22532.1 446 KLTVIDVSALLSESIRRHHYGER 468
                     78889***************995 PP

>> Pribosyltran  Phosphoribosyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.3   0.0     0.001       6.2      21      75 ..     154     209 ..     142     232 .. 0.83
   2 !   22.7   0.1   9.2e-09   5.5e-05      60     132 ..     343     419 ..     319     439 .. 0.72

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.001
                   EEEEE.--GGGEEEEEEETTTHHHHHHHHHHSTT-EE-EEEEEE-TTT--EE.... CS
  Pribosyltran  21 eilee.yngkpdvvvgiargGvpfakiladeLevplayvrkvkyrpdgseeaargs 75 
                   +i+++   ++  vvv    gG  +++ lad L++ + +v  +++rp++  +++ ++
    EEA22532.1 154 WIRMNvPSWRDAVVVSKNAGGTKRVTSLADTLKLNFGIVTTERRRPKVHMSMTDSM 209
                   4444444478889*********************************9998887765 PP

  == domain 2  score: 22.7 bits;  conditional E-value: 9.2e-09
                   EEEE-TTT--EE.........EE----TTSEEEEE-SEESSSHHHHHHHH.HHHCC-BSEEEEEEEE...E-HHHHHH CS
  Pribosyltran  60 kvkyrpdgseeaargssdes.rlledpagkkVliVDDildtGgTllaale.lLkekgpeevriavlv...dkpateee 132
                   +++ ++d  + +a+++ + + +l +++++k V+i+DD++d  g+ + a+e  +++ g++ v +++ +    +++ ee 
    EEA22532.1 343 VES-DDDEPPAMATNNDEKTiTLVGNVKDKAVFIIDDMIDRSGSWITAAEtVVRRGGAKTVYCIATHglfGNNCLEEM 419
                   344.444444444443333369*******************999999999999******8888877655344444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (476 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       422  (0.0235373); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.68u 0.35s 00:00:01.03 Elapsed: 00:00:00.56
# Mc/sec: 2550.35
//
Query:       EEA22533.1  [L=237]
Description: siroheme synthase Met8, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.7e-33  114.5   0.0    4.5e-33  113.8   0.0    1.4  1  NAD_binding_7   Putative NAD(P)-binding
    1.3e-31  108.1   0.1      2e-31  107.4   0.1    1.3  1  Sirohm_synth_C  Sirohaem biosynthesis protein C-terminal
    1.5e-14   53.1   0.1    1.5e-14   53.1   0.1    1.7  2  Sirohm_synth_M  Sirohaem biosynthesis protein central
      0.002   18.2   0.0     0.0032   17.5   0.0    1.3  1  Shikimate_DH    Shikimate / quinate 5-dehydrogenase
     0.0023   18.2   0.1     0.0046   17.2   0.1    1.5  1  TrkA_N          TrkA-N domain
     0.0034   16.7   0.1     0.0048   16.2   0.1    1.2  1  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
     0.0085   15.4   0.0      0.012   14.9   0.0    1.2  1  AlaDh_PNT_C     Alanine dehydrogenase/PNT, C-terminal domain
  ------ inclusion threshold ------
       0.03   13.7   2.2       0.11   11.8   0.1    2.3  3  ThiF            ThiF family
      0.048   13.8   0.0      0.086   13.0   0.0    1.4  1  FBA_2           F-box associated
      0.053   13.5   0.0       0.17   11.9   0.0    1.7  2  DUF5444         Family of unknown function (DUF5444)
      0.055   12.7   0.0      0.082   12.1   0.0    1.2  1  LSDAT_prok      SLOG in TRPM, prokaryote


Domain annotation for each model (and alignments):
>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.8   0.0   2.7e-36   4.5e-33       1     104 []      16     127 ..      16     127 .. 0.91

  Alignments for each domain:
  == domain 1  score: 113.8 bits;  conditional E-value: 2.7e-36
  NAD_binding_7   1 lfldlkgkkvlvvGgGevAarkvrklleagakvtvvapev..keele.......elvklaeeele.kdlegadlviaatddrelneriaeaakarr 86 
                    +++++++k+vlvvGgGevA  ++ + l+a+akvtvv p++  +e  e       ++v++ ++++e +dl++ad+v++a+dd+e ++++++++k+rr
     EEA22533.1  16 VAWQIRNKHVLVVGGGEVASGRILHALNADAKVTVVCPKSglNE--EvayrvaqNQVSHVDRNFEpHDLDNADMVLCAIDDPEASTQVWKLCKERR 109
                    68*************************************86633..23356666888888999955****************************** PP

  NAD_binding_7  87 ilvnvadkpelcdfifpa 104
                    i+ n+ad p++cdf+f++
     EEA22533.1 110 IPANIADVPPECDFYFGS 127
                    ****************97 PP

>> Sirohm_synth_C  Sirohaem biosynthesis protein C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  107.4   0.1   1.2e-34     2e-31       1      68 []     160     227 ..     160     227 .. 0.99

  Alignments for each domain:
  == domain 1  score: 107.4 bits;  conditional E-value: 1.2e-34
  Sirohm_synth_C   1 PdnlgaAiekvgkLRkkLReiapdqeegpkRMkWmskvcdswsleelaeldeedmekLlemyekgkvp 68 
                     P+n+gaAie+vg LRkkLReiapd++egpkRMkWms+vc swsle+l+ ++++dm++Ll++y++g+vp
      EEA22533.1 160 PQNTGAAIENVGLLRKKLREIAPDTQEGPKRMKWMSNVCVSWSLEDLVAMTDKDMDRLLKHYQTGEVP 227
                     89***************************************************************997 PP

>> Sirohm_synth_M  Sirohaem biosynthesis protein central
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.1   0.1   9.5e-18   1.5e-14       1      27 [.     131     157 ..     131     158 .. 0.96
   2 ?   -2.4   0.3       2.2   3.5e+03      20      27 ..     172     179 ..     171     180 .. 0.79

  Alignments for each domain:
  == domain 1  score: 53.1 bits;  conditional E-value: 9.5e-18
  Sirohm_synth_M   1 rGpLQIaiSTnGksPrLAaliRreier 27 
                     +GpLQI++STnG++P+LA+++R++i++
      EEA22533.1 131 DGPLQIMVSTNGNGPKLANIVRQKIAS 157
                     8************************97 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 2.2
  Sirohm_synth_M  20 liRreier 27 
                     l+R+++ +
      EEA22533.1 172 LLRKKLRE 179
                     79999975 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   0.0   1.9e-06    0.0032       9      88 ..      19      97 ..      13     117 .. 0.90

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 1.9e-06
                  ..TT-EEEEES-SHHHHHHHHHHHCCT-CEEEEEESSHHHHHHHHHHHT.ET-EEEEGCGHHHHHHT-SEEEE-SSSSS- CS
  Shikimate_DH  9 slkekkvlliGaGemaelvakhLlakgvkkvvvaNRtlerakelaeelkgeeiealkleelkellaeadvvisataseep 88
                  ++++k+vl++G Ge+a+  + h l++ +k v+v+       +e+a ++ +++++ ++ +   + l++ad+v++a+  +e+
    EEA22533.1 19 QIRNKHVLVVGGGEVASGRILHALNADAK-VTVVCPKSGLNEEVAYRVAQNQVSHVDRNFEPHDLDNADMVLCAIDDPEA 97
                  57899**********************99.99999999999*******9999999999999999**********988765 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.1   2.8e-06    0.0046       1      87 [.      25     109 ..      25     117 .. 0.80

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 2.8e-06
                 EEEES-SHHHH.HHHHHHHHTTEEEEEEESSHHHHHHHHHTTSEEEES-TTSHH.HHHHTTGGGESEEEE-SSSHHHHHHHHHHHHHHT CS
      TrkA_N   1 iiiiGlGrvGr.slaeeLseggkdvvvidkdeerveelreeglevvvgdatdee.vLeeagiekadaviaatgddeanilavllakeln 87 
                 ++++G G+v++ ++++ L+++  +v+v+  +    ee++   ++v + ++++ +   e  ++++ad+v++a++d ea++ + +l+ke +
  EEA22533.1  25 VLVVGGGEVASgRILHALNADA-KVTVVCPKSGLNEEVA---YRVAQNQVSHVDrNFEPHDLDNADMVLCAIDDPEASTQVWKLCKERR 109
                 6899***998736889998888.5******988777777...6777777776651467789**********************999854 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.1     3e-06    0.0048     159     210 ..      18      65 ..      10      91 .. 0.86

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 3e-06
  Pyr_redox_3 159 fhkyagqkvvViGgknSavDaAlelvrkgaeVtvvtrgseiekeesdpsysl 210
                  + ++++++v+V+Gg++ a    l+  +++a+Vtvv ++s +++e   + y++
   EEA22533.1  18 W-QIRNKHVLVVGGGEVASGRILHALNADAKVTVVCPKSGLNEE---VAYRV 65 
                  5.7899********************************998886...45554 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   7.6e-06     0.012      14     102 ..      11      95 ..       2     108 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 7.6e-06
                  TSEEETTCEETCB---EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHHHHHHHHHTTTCECEEHCHHHHHHHHHHHH-SEEEE---BT CS
  AlaDh_PNT_C  14 ggkgtlaGgvpgvepakvlviGgGvaGlqAiatakglgakVtvlDvrparleqleslgakfvevlksqeellaeavkeadvvigtvlip 102
                  gg+ ++a +++   + +vlv+GgG +    i  a + +akVtv+  ++   e++    a+  +v + +++   + + +ad+v +++  p
   EEA22533.1  11 GGSLIVAWQIR---NKHVLVVGGGEVASGRILHALNADAKVTVVCPKSGLNEEVAYRVAQ-NQVSHVDRNFEPHDLDNADMVLCAIDDP 95 
                  45555555666...99***************************************95555.477778888888999********98655 PP

>> ThiF  ThiF family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.2      0.12     2e+02      15      31 ..      19      35 ..      16      42 .. 0.86
   2 ?   11.8   0.1     7e-05      0.11      87     137 ..      60     112 ..      34     118 .. 0.63
   3 ?   -2.8   0.0         2   3.2e+03      77     100 ..     173     196 ..     147     210 .. 0.71

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.12
                HHHTSEEEEE--SHHHH CS
                xxxxxxxxxxxxxxxxx RF
        ThiF 15 kLrdskvllvGaGglGs 31
                ++r+++vl+vG G + s
  EEA22533.1 19 QIRNKHVLVVGGGEVAS 35
                699********998865 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 7e-05
                 TSEEEEEES-CCG..CCS-HHHHTT-SEEEEESSSHHHHHHHHHHHHHHT-EE CS
                 xxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        ThiF  87 dveveavteritd..etvleellesvDlVvdalDniearrlvnracvkkgipl 137
                 +v  +  +++++   ++++ + l ++D+V+ a+D  ea   v ++c +++ip 
  EEA22533.1  60 EVAYRVAQNQVSHvdRNFEPHDLDNADMVLCAIDDPEASTQVWKLCKERRIPA 112
                 22222222222222122444448888************************995 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 2
                 HHHHHHHT-TTSEEEEEES-CCGC CS
                 xxxxxxxxxxxxxxxxxxxxxxxx RF
        ThiF  77 aaealqeinpdveveavteritde 100
                 ++++l+ei+pd++  + +++++++
  EEA22533.1 173 LRKKLREIAPDTQEGPKRMKWMSN 196
                 567777777777777777776665 PP

>> FBA_2  F-box associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   5.3e-05     0.086      31      64 ..     198     232 ..     192     233 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 5.3e-05
       FBA_2  31 sksleldnss.lsskdlNrFLKhWikgsnprLeyl 64 
                 + s +l++   +++kd+ r LKh + g+ p L ++
  EEA22533.1 198 CVSWSLEDLVaMTDKDMDRLLKHYQTGEVPSLDDI 232
                 566667776769******************99876 PP

>> DUF5444  Family of unknown function (DUF5444)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       2.8   4.5e+03      26      40 ..       4      18 ..       2      21 .. 0.79
   2 ?   11.9   0.0   0.00011      0.17      27      49 ..     181     202 ..     170     208 .. 0.85

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 2.8
     DUF5444 26 sfPdteeGlkeayeW 40
                 fP+ + G +  ++W
  EEA22533.1  4 KFPEVQGGGSLIVAW 18
                599999999888888 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 0.00011
     DUF5444  27 fPdteeGlkeayeWaseiavGWh 49 
                  Pdt+eG k  ++W s+++v W 
  EEA22533.1 181 APDTQEGPKR-MKWMSNVCVSWS 202
                 4******986.89*********5 PP

>> LSDAT_prok  SLOG in TRPM, prokaryote
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0     5e-05     0.082     123     173 ..      21      71 ..      13      95 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 5e-05
  LSDAT_prok 123 kpsvtvlvnGgeitlkdiresvkagrpilvvaGsgrladeiaaalrgdsee 173
                 +++ +++v+Gge++   i ++++a+ ++ vv    +l++e+a ++ +++ +
  EEA22533.1  21 RNKHVLVVGGGEVASGRILHALNADAKVTVVCPKSGLNEEVAYRVAQNQVS 71 
                 57889***************************9999****98888555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (237 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       521  (0.0290591); expected 358.6 (0.02)
Passed bias filter:                      499  (0.027832); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.63u 0.38s 00:00:01.01 Elapsed: 00:00:00.57
# Mc/sec: 1242.52
//
Query:       EEA22534.1  [L=1976]
Description: guanyl-nucleotide exchange factor (Sec7), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.5e-72  241.1   0.4    2.3e-71  239.3   0.4    2.1  1  Sec7      Sec7 domain
    1.5e-43  148.4   6.2    1.5e-43  148.4   6.2    3.1  3  Sec7_N    Guanine nucleotide exchange factor in Golgi transpo
    1.4e-33  114.6  11.7    1.5e-33  114.5   0.1    5.6  6  DUF1981   Domain of unknown function (DUF1981)
    3.5e-17   62.6   1.9    3.7e-16   59.3   0.3    3.2  3  DCB       Dimerisation and cyclophilin-binding domain of Mon2


Domain annotation for each model (and alignments):
>> Sec7  Sec7 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  239.3   0.4   5.1e-75   2.3e-71       1     183 []     775     959 ..     775     959 .. 0.98

  Alignments for each domain:
  == domain 1  score: 239.3 bits;  conditional E-value: 5.1e-75
                 HHHHHHHHHHHHHH-HHHHHHHHHHCCCC.TSSHHHHHHHHHHTCCS-HHHHHHHHCSGGHHHHHHHHHHHCTS--TT--HHHHHHHHCCCS-B-SSHH CS
        Sec7   1 rkklleeaaekFnkkpkkgikyliekgll.eedpksiakflketpgldkkklGeylgkekefnkevlkefvdlfdfsglrldeAlRlflssfrlpgEaq 98 
                 rk  l++a+++Fn kpk+gik l + g++ +++pk+ia+fl ++++ldk+++Geylg+ ++ n+ ++++fvd++df++ r+++AlR+fl+sfrlpgEaq
  EEA22534.1 775 RKAALSHAIQQFNFKPKRGIKLLLKDGFIrSDSPKDIASFLLRNDRLDKAMIGEYLGEGDPENVAIMHAFVDTMDFTKRRFVDALRQFLQSFRLPGEAQ 873
                 68899************************6666****************************************************************** PP

                 HHHHHHHHHHHHHHHTTCTCG-SHHHHHHHHHHHHHHHHHHC-TTS.CCS--HHHHHHCTTTTBTTB---HHHHHHHHHHHHHS-- CS
        Sec7  99 kierilekFaekyfeqnpevfenadavfvLaysiimLntdlhnpqv.kkkmtledFiknnrgindgkdlpeefLeeiYdsIkeeei 183
                 ki+r++ kFae+y + np++f+nad+++vLays+imLntd+h++++   +mt+edFiknnrgind+ dlp+e+L++i+d+I+++ei
  EEA22534.1 874 KIDRFMLKFAERYLAGNPNSFANADTAYVLAYSVIMLNTDQHSSKLkGPRMTKEDFIKNNRGINDNADLPDEYLNSIFDEIAKNEI 959
                 **********************************************559****************99*****************98 PP

>> Sec7_N  Guanine nucleotide exchange factor in Golgi transport N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0      0.51   2.3e+03      37      73 ..     247     282 ..     237     316 .. 0.74
   2 !  148.4   6.2   3.4e-47   1.5e-43       1     155 [.     445     615 ..     445     617 .. 0.95
   3 ?    0.3   0.1      0.13   5.6e+02      81     128 ..    1569    1622 ..    1512    1634 .. 0.71

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.51
      Sec7_N  37 LeLlesvlsnhgdvfrkhpellqllkqklcplLlknl 73 
                 L L+e ++++  d f+ ++     ++q+++++Ll  +
  EEA22534.1 247 LPLIERAIETICDCFE-NEATPVEIQQQIIKSLLAAV 282
                 7899999999999995.44555556777777777655 PP

  == domain 2  score: 148.4 bits;  conditional E-value: 3.4e-47
      Sec7_N   1 aakDaflvfrdLcklinsaks.....kpkflslaersktfsLeLlesvlsnhgdvfr.............khpellqllkqklcplLlknlsespsfpv 81 
                 ++kDaflvfr++ckl  s+k+     ++ + s+++rsk++sL+L++++++nh +vf+             +  +ll++++ +lc +L++n  +s++++v
  EEA22534.1 445 YVKDAFLVFRAMCKL--SHKTlthdqQQDIKSQNMRSKLLSLHLIHHLINNHITVFTsplatirnsasssDTITLLHAIRPHLCLSLSRNG-SSSVPKV 540
                 689************..788787764355459************************************9888999****************.9****** PP

      Sec7_N  82 ferslrivllLlkkfrseLktEievflsllililles.dsslwqrvlaLeilrrlcsdpqllvelylnYDcdeea 155
                 fe++++i++l+lk++r +Lk+E+evfl++++l +le  +s++ q+ +++eil+rl++d+++lve+ylnYDcd++a
  EEA22534.1 541 FEVCCEIFWLMLKYMRVMLKKELEVFLKEIYLAILERrNSPAFQKQYFMEILERLSGDSRALVEIYLNYDCDRTA 615
                 ************************************99**********************************976 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.13
      Sec7_N   81 vferslrivllLlkkfrseLktEievflsllilillesdssl......wqrvla 128 
                  ++  +lr + +L++++ + L+  +  fl ll+l +++++ ++        + l+
  EEA22534.1 1569 TMIQALRHMITLFTHYFDALQGMLNRFLGLLNLCICQENDTIarigsnCLQQLI 1622
                  455689999999********************9999886665444444444555 PP

>> DUF1981  Domain of unknown function (DUF1981)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   0.1       2.9   1.3e+04      28      54 ..     474     500 ..     472     505 .. 0.80
   2 ?    0.9   0.0     0.094   4.2e+02      38      65 ..    1122    1149 ..    1111    1154 .. 0.86
   3 ?    1.3   0.1     0.069   3.1e+02      21      69 ..    1246    1294 ..    1232    1313 .. 0.80
   4 !  114.5   0.1   3.3e-37   1.5e-33       1      83 [.    1317    1399 ..    1317    1400 .. 0.98
   5 ?   -1.1   0.1       0.4   1.8e+03       8      25 ..    1426    1443 ..    1423    1449 .. 0.80
   6 ?   -0.5   0.0      0.25   1.1e+03      39      57 ..    1616    1635 ..    1593    1649 .. 0.61

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 2.9
     DUF1981  28 nssaeirelvlecveqliqsraeniks 54 
                 ++++  + l l+ +++li+++ +  +s
  EEA22534.1 474 SQNMRSKLLSLHLIHHLINNHITVFTS 500
                 577788899999999**9999877665 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.094
     DUF1981   38 lecveqliqsraeniksGWktifgvlta 65  
                  l+++ ++  +++++++  W+ i++++++
  EEA22534.1 1122 LKILLEVAVTEGNHLRDSWREILTCVSQ 1149
                  667778888999***********99876 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.069
     DUF1981   21 FeeimsnnssaeirelvlecveqliqsraeniksGWktifgvltaaake 69  
                  ++ei s+ +s+  r + l+ v ++   +++ ++  W  i+++l+   +e
  EEA22534.1 1246 LQEIQSSGQSESPRTYSLQKVVEISYYNMTRVRIEWSRIWEILGRHFNE 1294
                  56777888888899999*************************9876643 PP

  == domain 4  score: 114.5 bits;  conditional E-value: 3.3e-37
     DUF1981    1 kflekeelsnfkfQkefLkPFeeimsnnssaeirelvlecveqliqsraeniksGWktifgvltaaakeeneslvrlafqilk 83  
                  +f+e+eel+ fkfQk+fLkPFe+im+n+++++++++vl+c+ q+iq+r++ni+sGWkt+fgv+t+aa+e  e +v++af+ ++
  EEA22534.1 1317 RFMEIEELPGFKFQKDFLKPFEHIMANSNTVTVKDMVLRCLIQMIQARGHNIRSGWKTMFGVFTVAAREPYEGIVNMAFEHVT 1399
                  69*****************************************************************************9875 PP

  == domain 5  score: -1.1 bits;  conditional E-value: 0.4
     DUF1981    8 lsnfkfQkefLkPFeeim 25  
                   +n kfQk+ L+  e++ 
  EEA22534.1 1426 SKNIKFQKKSLQAIETLK 1443
                  5799*******9998875 PP

  == domain 6  score: -0.5 bits;  conditional E-value: 0.25
     DUF1981   39 ecveqliqsraeni.ksGWk 57  
                  +c++qli +++++     W 
  EEA22534.1 1616 NCLQQLILQNVTKFsDEHWG 1635
                  56666666666665334444 PP

>> DCB  Dimerisation and cyclophilin-binding domain of Mon2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.3   0.3   8.3e-20   3.7e-16      11     175 ..     154     333 ..     147     335 .. 0.84
   2 ?   -1.3   0.0      0.32   1.5e+03      57      88 ..    1330    1362 ..    1294    1381 .. 0.51
   3 ?   -0.3   0.0      0.16   7.1e+02      71     110 ..    1606    1647 ..    1555    1653 .. 0.75

  Alignments for each domain:
  == domain 1  score: 59.3 bits;  conditional E-value: 8.3e-20
         DCB  11 qsdlkals.seskrkhskvkeasekgilkLktikssseeeeqslaeaseeilkPlllacetknpkivqiaLgslqrLishevis..eea.......... 96 
                 ++ l+a++ s   ++++ +++a++k++ ++k+ ++++      l  +   i+ Pl la +t +  +  +aL+++ +Li++++    +++          
  EEA22534.1 154 VTALEAIAaSKDAKRNKALEDAVQKALANIKQSDTKP------LDPE--VIFLPLQLATKTFSIPLQVTALDCIGKLITYSYFAfpSSRpgqddkdpan 244
                 5666666513445778888888888888888888888......6555..9*******************************998663335566677888 PP

         DCB  97 .....iskiietlwkllelgve...ielkvLqtllllvttss.vvhgdtlakalvlCfrL.hfskdnvvqntAaAtlrQlvsvvFeRvv 175
                      i++ iet+++++e++     i+ +++++ll +v  ++ vvhg  l+ka++  +++   sk++ +q++A+ +l+Q++ +vF+Rv 
  EEA22534.1 245 kelplIERAIETICDCFENEATpveIQQQIIKSLLAAVLNDKiVVHGAGLLKAVRQIYNIfIYSKSSQNQQIAQGSLTQMLGTVFDRVR 333
                 89999*************9754444999**************9*****************7788888********************95 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.32
         DCB   57 seeilkPlllac.etknpkivqiaLgslqrLis 88  
                   +++lkP+     ++  + + ++ L +l ++i+
  EEA22534.1 1330 QKDFLKPFEHIMaNSNTVTVKDMVLRCLIQMIQ 1362
                  245555554332134444444555555555554 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.16
         DCB   71 knpkivqiaLgslqrLishevis..eeaiskiietlwkllel 110 
                   n  i  i  ++lq+Li ++v +  +e+  ki+ ++++l++ 
  EEA22534.1 1606 ENDTIARIGSNCLQQLILQNVTKfsDEHWGKIVGAFVELFDK 1647
                  456677788899999999888654477789999999888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1976 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       913  (0.0509231); expected 358.6 (0.02)
Passed bias filter:                      528  (0.0294495); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 1.20u 0.38s 00:00:01.58 Elapsed: 00:00:00.59
# Mc/sec: 10164.55
//
Query:       EEA22535.1  [L=472]
Description: pyruvate dehydrogenase complex, dihydrolipoamide acetyltransferase component, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.6e-79  265.9   0.1    3.5e-79  265.5   0.1    1.2  1  2-oxoacid_dh   2-oxoacid dehydrogenases acyltransferase (cata
    4.4e-17   61.7   2.4    8.8e-17   60.7   0.3    2.3  2  Biotin_lipoyl  Biotin-requiring enzyme
    9.8e-13   48.2   0.3    9.8e-13   48.2   0.3    2.7  3  E3_binding     e3 binding domain


Domain annotation for each model (and alignments):
>> 2-oxoacid_dh  2-oxoacid dehydrogenases acyltransferase (catalytic domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  265.5   0.1   5.9e-83   3.5e-79       4     233 .]     238     472 .]     235     472 .] 0.94

  Alignments for each domain:
  == domain 1  score: 265.5 bits;  conditional E-value: 5.9e-83
                   XXXXXXXXXXXXXXXXXXXXX.XXXEEEEEEEEE-HHHHHHHHHHHHHHHHTT-----HHHHHHHHHHHHHHH-GGGG-EE.EES..EEEE--SS-- CS
  2-oxoacid_dh   4 eervplsgirkaiakrlteskqeiphftlsdevdvtallelrkelkekeakeekakltlldflikavalAlkefPelnasvdeee..keivvkkhvn 98 
                    e++pl+ +rk+ia+rl++s qe ph+ +s ++ vt+ll+lr+ l++++    k+kl+++dflika+++Al+++P++n+s++ee+    i+++++v+
    EEA22535.1 238 FEDIPLTSMRKTIAARLQKSTQENPHYFVSTTLSVTKLLKLRQALNASADG--KYKLSVNDFLIKACSIALRKVPAVNSSWTEENgqTIIRQYNNVD 332
                   689********************************************9964..45**************************8887534567899*** PP

                   EEEE--------EEEE--GGG--HHHHHHHHHHHHHHHTTT---GGGTSS-SEEEE------.---------TT-SEEEEE---.B--TTSTT-... CS
  2-oxoacid_dh  99 iGvAvatprGLlvPviknadkkslleiakelkelaekaregklkpedleggtftisNlGmlG.vtsftPiinppqvaIlgvgrikerpvvkege... 191
                   i+vAvatp GL++P++kna++++l++i++ +k+l ++ar++klkpe+++ggtftisNlGm + v+ ft++inppq+aIl+vg++++++v +e+e   
    EEA22535.1 333 ISVAVATPAGLITPIVKNAHNLGLSSISNTVKDLGKRARDNKLKPEEYQGGTFTISNLGMNNaVERFTAVINPPQAAILAVGTTRKVAVPVETEegt 429
                   **************************************************************9*********************9988775555578 PP

                   .HT---EEEEEEEEETTT--HHHHHHHHHHHHHTT-HHXXXXX CS
  2-oxoacid_dh 192 .lvvrkvmtlslsaDHRvidGaeaarFlntlkkllenpeelll 233
                    ++    + ++ s+DHRvidGa + +++++lkk++enp el+l
    EEA22535.1 430 sVEWDDQIIVTASFDHRVIDGAVGGEWIKELKKVVENPLELML 472
                   9***************************************996 PP

>> Biotin_lipoyl  Biotin-requiring enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.7   0.3   1.5e-20   8.8e-17       3      73 .]      50     122 ..      48     122 .. 0.98
   2 ?   -0.3   0.1      0.16   9.8e+02      17      34 ..     421     438 ..     412     440 .. 0.59

  Alignments for each domain:
  == domain 1  score: 60.7 bits;  conditional E-value: 1.5e-20
                    EEESSSEEEEEE..ECSESSSTTCEE-TTSEEEEEECTTEEEEEEBSSSEEEEEESSTTTEE.E-TTCEEEEE CS
  Biotin_lipoyl   3 iksPmiGesveeg.vvevlvkvGdkVkagqvlaeveamKmemeieapkaGvvkeilvkeGdt.vevgdllaki 73 
                    i++P++++++++g + ++ +k+Gd+ + g+vl+e+e++K++m++e +++Gv++++l+++G++ v vg+++a++
     EEA22535.1  50 ISMPALSPTMTAGnIGSWQKKAGDALAPGDVLVEIETDKAQMDFEFQDEGVLAKVLKDSGEKdVAVGTPIAVL 122
                    89********************************************************************986 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.16
                    CSESSSTTCEE-TTSEEE CS
  Biotin_lipoyl  17 vevlvkvGdkVkagqvla 34 
                    v v  ++G +V+ ++ ++
     EEA22535.1 421 VPVETEEGTSVEWDDQII 438
                    455556666666666554 PP

>> E3_binding  e3 binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.9       1.1   6.7e+03       5      12 ..      30      37 ..      28      38 .. 0.87
   2 !   48.2   0.3   1.6e-16   9.8e-13       3      36 .]     191     224 ..     189     224 .. 0.96
   3 ?   -3.3   0.0         2   1.2e+04      14      27 ..     329     341 ..     329     345 .. 0.58

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 1.1
                HHHHHHHH CS
  E3_binding  5 PaaRklAk 12
                Pa++ lA+
  EEA22535.1 30 PAVSALAR 37
                *******8 PP

  == domain 2  score: 48.2 bits;  conditional E-value: 1.6e-16
                 E-HHHHHHHHHCT--TTTS---CTTTBE-HHHHC CS
  E3_binding   3 AsPaaRklAkelGidLsdvkGtGpgGRItkeDVl 36 
                 +sPaa+ lA e+Gi+++++kGtG+gG ItkeDV+
  EEA22535.1 191 ISPAAKALALEKGISIKALKGTGRGGQITKEDVE 224
                 7********************************7 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 2
                 CT--TTTS---CTT CS
  E3_binding  14 lGidLsdvkGtGpg 27 
                 +++d+s  ++t p 
  EEA22535.1 329 NNVDISVAVAT-PA 341
                 67888844455.44 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (472 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       530  (0.029561); expected 358.6 (0.02)
Passed bias filter:                      424  (0.0236488); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 2995.64
//
Query:       EEA22536.1  [L=219]
Description: hypothetical protein PMAA_091630 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.043   12.6   0.1      0.047   12.5   0.1    1.1  1  SAPS      SIT4 phosphatase-associated protein
      0.067   13.2   0.2      0.083   12.9   0.2    1.2  1  CENP-O    Cenp-O kinetochore centromere component


Domain annotation for each model (and alignments):
>> SAPS  SIT4 phosphatase-associated protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.1   5.2e-06     0.047     319     409 ..      11     111 ..       2     147 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 5.2e-06
        SAPS 319 sseededdasseesalaeeteeklr..........kkpvvGDl.LKiklvelkilptiLdlFfkYpwNNfLHnvVydivqqilngkmdrgynrfLavdL 406
                  ++++++d+ ++ +++ ++t ++l           ++ +++ + L + l+e++++p++ +l ++Y     LH+  yd+v   ln + drg+nr++ v++
  EEA22536.1  11 RVNDNDNDNDNIIEVKWKQTSPSLIqdlyrslihkQRSTIHAFhLWLRLLEHNLMPNVRELTVHYHTVPSLHTE-YDLVRIWLNANPDRGLNRKMRVQI 108
                 344444444444444444444444446666777766666766448899************************98.**********************99 PP

        SAPS 407 fek 409
                 +  
  EEA22536.1 109 LAF 111
                 854 PP

>> CENP-O  Cenp-O kinetochore centromere component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.2   9.2e-06     0.083      49     114 ..      52     155 ..       9     173 .. 0.74

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 9.2e-06
      CENP-O  49 e..................lrvhrHTvPafipLaklearylpap....................eeeeeakkkkektrkqdLkkFvrelrreLvayhnR 109
                 +                  l+vh HTvP      +l + +l a+                    +++++ +++   ++k   + F+r++r++   +h++
  EEA22536.1  52 AfhlwlrllehnlmpnvreLTVHYHTVPSLHTEYDLVRIWLNANpdrglnrkmrvqilafalasASSSSGASDGGDEKKIPWNLFLRDMRHQHDLIHDK 150
                 2333333333344445556***********9999*******7778999**********99995444444444444455555599999999999999999 PP

      CENP-O 110 ldave 114
                 +d + 
  EEA22536.1 151 HDLIG 155
                 98775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (219 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       367  (0.0204696); expected 358.6 (0.02)
Passed bias filter:                      300  (0.0167327); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.41u 0.23s 00:00:00.64 Elapsed: 00:00:00.39
# Mc/sec: 1691.76
//
Query:       EEA22537.1  [L=830]
Description: phospholipase PldA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-15   57.5   0.2    3.6e-06   26.9   0.0    3.5  3  PLDc_2    PLD-like domain
    7.6e-14   51.2   2.8    4.1e-08   33.1   0.1    2.6  2  PLDc      Phospholipase D Active site motif


Domain annotation for each model (and alignments):
>> PLDc_2  PLD-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0     1e-06     0.009       5     101 ..      90     215 ..      87     230 .. 0.65
   2 !   10.7   0.0   4.1e-05      0.36       3      43 ..     385     438 ..     383     467 .. 0.92
   3 !   26.9   0.0     4e-10   3.6e-06      80     122 ..     619     663 ..     500     668 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 1e-06
      PLDc_2   5 iksAkksidiatyyf..........vsdrei.ldallk.aakrgvkvrilldskkd.....................dagavdeaslkelkellleagv 70 
                 +++Ak++i+ia   +          + ++e  ld++lk  a+ gv++ +++ ++ d                     +      + +++++ l ++   
  EEA22537.1  90 LDRAKETIYIADWWLspelflrrppNLNQEWrLDHVLKrRAEAGVQIYVIVYKEVDraltcnsahtkhalrnlcpegS------KGAGNIHVL-RHPDH 181
                 788899999988888777777777733333358888666*************98888888866666666654433332......223333333.33333 PP

      PLDc_2  71 evrvfetll.......gslHaKlylidgktvivGSsNl 101
                 ++ +    +          H+K+++id +++++G+  l
  EEA22537.1 182 NIFE----NlgdmtfyWAHHEKFVVIDYEIAFIGGIDL 215
                 3222....02222233456***************9765 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 4.1e-05
      PLDc_2   3 qliksAkksidiatyyf.............vsdreildallkaakrgvkvrill 43 
                 + i++A+++++i +++f                r+i++a+++a k+g+k r+++
  EEA22537.1 385 EIISKAEHYVYIENQFFvtatgdqqhpvqnTIGRAIVEAVVRAGKEGRKFRVII 438
                 679****************99999988887778889****************96 PP

  == domain 3  score: 26.9 bits;  conditional E-value: 4e-10
      PLDc_2  80 gslHaKlylidgktvivGSsNltkrgl..dlnlElnvviedkela 122
                   +H+Kl+++d+++ i GS+N+++r+   d++ El++v+ed +++
  EEA22537.1 619 LYVHDKLCIVDDRIIICGSANINDRSQlgDRDSELAIVLEDTDMI 663
                 678***********************9888888999999998766 PP

>> PLDc  Phospholipase D Active site motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.1   0.1   4.5e-12   4.1e-08       3      28 .]     194     219 ..     193     219 .. 0.97
   2 !   17.8   0.5   3.1e-07    0.0028       5      28 .]     621     644 ..     619     644 .. 0.94

  Alignments for each domain:
  == domain 1  score: 33.1 bits;  conditional E-value: 4.5e-12
                 BEE---EEEETTTEEEEE---SSHHH CS
        PLDc   3 gthHqKivivDdrvafvGgaNLcdgr 28 
                 + hH+K+v++D ++af+Gg +Lc gr
  EEA22537.1 194 WAHHEKFVVIDYEIAFIGGIDLCFGR 219
                 99*********************997 PP

  == domain 2  score: 17.8 bits;  conditional E-value: 3.1e-07
                 E---EEEETTTEEEEE---SSHHH CS
        PLDc   5 hHqKivivDdrvafvGgaNLcdgr 28 
                 +H K  ivDdr+ + G+aN++d++
  EEA22537.1 621 VHDKLCIVDDRIIICGSANINDRS 644
                 799*******************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (830 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       751  (0.0418874); expected 358.6 (0.02)
Passed bias filter:                      448  (0.0249875); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.70u 0.28s 00:00:00.98 Elapsed: 00:00:00.46
# Mc/sec: 5408.35
//
Query:       EEA22538.1  [L=644]
Description: phospholipase PldA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-14   53.1   2.5      3e-08   33.5   0.1    2.6  2  PLDc      Phospholipase D Active site motif
      2e-13   50.3   0.1     0.0012   18.8   0.0    3.5  3  PLDc_2    PLD-like domain


Domain annotation for each model (and alignments):
>> PLDc  Phospholipase D Active site motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.5   0.1   3.4e-12     3e-08       3      28 .]     194     219 ..     193     219 .. 0.97
   2 !   19.0   0.4   1.3e-07    0.0012       5      28 .]     621     644 .]     619     644 .] 0.95

  Alignments for each domain:
  == domain 1  score: 33.5 bits;  conditional E-value: 3.4e-12
                 BEE---EEEETTTEEEEE---SSHHH CS
        PLDc   3 gthHqKivivDdrvafvGgaNLcdgr 28 
                 + hH+K+v++D ++af+Gg +Lc gr
  EEA22538.1 194 WAHHEKFVVIDYEIAFIGGIDLCFGR 219
                 99*********************997 PP

  == domain 2  score: 19.0 bits;  conditional E-value: 1.3e-07
                 E---EEEETTTEEEEE---SSHHH CS
        PLDc   5 hHqKivivDdrvafvGgaNLcdgr 28 
                 +H K  ivDdr+ + G+aN++d+r
  EEA22538.1 621 VHDKLCIVDDRIIICGSANINDRR 644
                 799********************8 PP

>> PLDc_2  PLD-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   6.6e-07    0.0059       5     101 ..      90     215 ..      87     231 .. 0.65
   2 !   11.2   0.0   2.9e-05      0.26       3      43 ..     385     438 ..     383     469 .. 0.92
   3 !   18.8   0.0   1.3e-07    0.0012      80     104 ..     619     643 ..     494     644 .] 0.84

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 6.6e-07
      PLDc_2   5 iksAkksidiatyyf..........vsdrei.ldallk.aakrgvkvrilldskkd.....................dagavdeaslkelkellleagv 70 
                 +++Ak++i+ia   +          + ++e  ld++lk  a+ gv++ +++ ++ d                     +      + +++++ l ++   
  EEA22538.1  90 LDRAKETIYIADWWLspelflrrppNLNQEWrLDHVLKrRAEAGVQIYVIVYKEVDraltcnsahtkhalrnlcpegS------KGAGNIHVL-RHPDH 181
                 788899999988888777777777733333358888666*************98888888866666666654433332......223333333.33333 PP

      PLDc_2  71 evrvfetll.......gslHaKlylidgktvivGSsNl 101
                 ++ +    +          H+K+++id +++++G+  l
  EEA22538.1 182 NIFE----NlgdmtfyWAHHEKFVVIDYEIAFIGGIDL 215
                 3222....02222233456***************9766 PP

  == domain 2  score: 11.2 bits;  conditional E-value: 2.9e-05
      PLDc_2   3 qliksAkksidiatyyf.............vsdreildallkaakrgvkvrill 43 
                 + i++A+++++i +++f                r+i++a+++a k+g+k r+++
  EEA22538.1 385 EIISKAEHYVYIENQFFvtatgdqqhpvqnTIGRAIVEAVVRAGKEGRKFRVII 438
                 679****************99999988887778889****************96 PP

  == domain 3  score: 18.8 bits;  conditional E-value: 1.3e-07
      PLDc_2  80 gslHaKlylidgktvivGSsNltkr 104
                   +H+Kl+++d+++ i GS+N+++r
  EEA22538.1 619 LYVHDKLCIVDDRIIICGSANINDR 643
                 678******************9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (644 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       824  (0.0459591); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.33s 00:00:00.90 Elapsed: 00:00:00.47
# Mc/sec: 4090.66
//
Query:       EEA22539.1  [L=434]
Description: DUF890 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.8e-63  214.0   0.0    3.8e-63  213.6   0.0    1.1  1  Methyltransf_10  RNA methyltransferase
    3.8e-05   23.3   0.0    6.9e-05   22.5   0.0    1.4  1  MTS              Methyltransferase small domain


Domain annotation for each model (and alignments):
>> Methyltransf_10  RNA methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  213.6   0.0   4.2e-67   3.8e-63       9     299 .]       4     286 ..       2     286 .. 0.90

  Alignments for each domain:
  == domain 1  score: 213.6 bits;  conditional E-value: 4.2e-67
                      TTXTTTTSXXHHHHHHHXHHHHTTXEEXTTSXEES-TTSHHHHHHHHHHHHHHHH----.---TTS----HHHHHHHHHHHHHHHTGGGSGTTS CS
  Methyltransf_10   9 prnrhkdkydfaalikvvPelkqfvilnpkGrvsidfadPlavkalnkallrefygvsewdiPdgfliPpvPgradyihyvadllgkadsdisa 102
                      +rn ++   df al+ ++Pe+ + ++ n      +df dP +v+ l+k+ll++++++   d+Pd++l+Pp+P r +yi +++dll  ++ + + 
       EEA22539.1   4 SRNIYRREIDFRALALTSPEFAKRLKSN----DQLDFSDPDSVRQLTKSLLERDFKLVV-DLPDDRLCPPIPNRFNYILWLQDLLDTSSRTGTD 92 
                      69*******************9877665....57***********************99.*************************887654222 PP

                      ......--EEEEES-TTTTHHHHHHHHHH.--EEEEEES-HHHHHHHHHHHHHT.T-TTTEEEEE--TT-SCCHHSSTTSS-EEEEEE-S---S CS
  Methyltransf_10 103 ......qvraldiGvGanCiyPllGvtey.GWrfvgsevddvslasakaivesnsklsdaiklrkqkekkaifdglieenerydvtlCnPPfha 189
                            qv +ldiG+G   iyPllG      Wrfv++++d   ++s++++v+ n kl+d i +   k +  ++       +r d+++CnPPf++
       EEA22539.1  93 qydlnrQVLGLDIGTGCCAIYPLLGCSSRpRWRFVATDIDGSNISSSRKVVSDN-KLDDRITILETKPNDPLIPIDRLDVDRLDFVMCNPPFYE 185
                      2333338999***************876528***********************.*********99999999877677778************* PP

                      S------------...---.....---------TTTSHHHHHHHHHHHHHHHHHHHHGGGEEEEEEEESSGGGHHHHHHHHHHTT-SEEEEEEE CS
  Methyltransf_10 190 slaeakagserklknlgkanktralpslnfgGqkaelyceGGevafikklieeskqlakqvlWfttlvskkenlaplkeelkklGaskvtvvel 283
                      s +e  ++++ k     +      +p +  +G   e++++GGevafi+ l+++s +l++++lW+t++ +k ++++ + ++l + G+++  v+e+
       EEA22539.1 186 SEEELVSSARAKS----R------PPFSACTGAAVEMITPGGEVAFIESLVQQSLALKTHILWYTSMFGKLSSVSVVVQKLLDSGINNWAVTEF 269
                      *999876665555....4......58999***************************************************************** PP

                      EETT.EEEEEEEEES-- CS
  Methyltransf_10 284 aqGq.klsrfiaWsfld 299
                      +qG+ + ++++ Wsf d
       EEA22539.1 270 VQGKgTRRWAVGWSFSD 286
                      ***9456799*****86 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5   0.0   7.7e-09   6.9e-05      32     113 ..      99     189 ..      78     239 .. 0.76

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 7.7e-09
                 CSEEEEET-TTSHHHHHH.HHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.....EEEEE-STT...TTSTTS-EEEEEE---STTTCHC CS
         MTS  32 sgkvlDlGcGaGvlgaal.akespeaevtlvdvdarAlesakenleankle.....vevvasdvl...eeveekkfdlivsNPPfhagkat 113
                 +   lD+G+G  ++   l  +  p+ + +++d+d   + s+++ +++nkl+     +e+  +d l   + ++ +++d++++NPPf +++++
  EEA22539.1  99 QVLGLDIGTGCCAIYPLLgCSSRPRWRFVATDIDGSNISSSRKVVSDNKLDdritiLETKPNDPLipiDRLDVDRLDFVMCNPPFYESEEE 189
                 333578888877776555156789999************************996666677777652225566799**********998764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (434 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       315  (0.0175693); expected 358.6 (0.02)
Passed bias filter:                      305  (0.0170115); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 3125.52
//
Query:       EEA22540.1  [L=191]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-33  114.7   3.6    1.6e-33  114.3   3.6    1.2  1  DUF5353   Family of unknown function (DUF5353)
  ------ inclusion threshold ------
      0.018   15.2   0.1      0.027   14.7   0.1    1.3  1  TrbC      TrbC/VIRB2 family
      0.034   13.8   0.0      0.043   13.5   0.0    1.1  1  DUF4203   Domain of unknown function (DUF4203)
       0.12   12.6   3.5       0.31   11.3   3.7    1.5  2  AP3D1     AP-3 complex subunit delta-1


Domain annotation for each model (and alignments):
>> DUF5353  Family of unknown function (DUF5353)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.3   3.6   3.5e-37   1.6e-33       1      68 []     123     190 ..     123     190 .. 0.99

  Alignments for each domain:
  == domain 1  score: 114.3 bits;  conditional E-value: 3.5e-37
     DUF5353   1 NkdnpvvvgNavlvavlsagLGfgAYrkyarGeLtwkvvglwagavGafavgdyyvskylfknkyppk 68 
                 N++npv++gNa +++++sa+LG+gAYrk+a+G+L+w+v+ +wagavG+fa +dy+vsk+l++nkyp+k
  EEA22540.1 123 NAENPVYLGNAFIITAVSAVLGYGAYRKHAEGKLSWEVASVWAGAVGLFAGADYFVSKWLLQNKYPTK 190
                 99****************************************************************98 PP

>> TrbC  TrbC/VIRB2 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.7   0.1     6e-06     0.027      26      98 ..     101     180 ..      96     181 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.7 bits;  conditional E-value: 6e-06
        TrbC  26 spalAqaagg....dpvetvlqnivdfltgplakviatiaiivaGimlafgrls....wrtlvmvviGiviifgAssivst 98 
                 + a A+++++    ++++++ +n  + +      +i+t + +v+G+++  ++++    w+ +  ++ +++++ gA  +vs+
  EEA22540.1 101 EKAAAASSSKkgkkSKAQELCKNAENPVYL-GNAFIITAVSAVLGYGAYRKHAEgklsWEVASVWAGAVGLFAGADYFVSK 180
                 555555555567777777777777777776.556677888889999998888888888********************997 PP

>> DUF4203  Domain of unknown function (DUF4203)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   9.7e-06     0.043     112     159 ..     134     183 ..     116     190 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 9.7e-06
     DUF4203 112 flvivvlgllgavlslkl..qklllivatsvvGaaavvlgiDyfvgaglk 159
                 f++ +v ++lg+ ++ k+   kl   va+ + Ga+ +++g Dyfv+++l 
  EEA22540.1 134 FIITAVSAVLGYGAYRKHaeGKLSWEVASVWAGAVGLFAGADYFVSKWLL 183
                 35688888888888888889999999********************9964 PP

>> AP3D1  AP-3 complex subunit delta-1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   3.7   6.8e-05      0.31      20     107 ..      30     117 ..      24     129 .. 0.44
   2 ?   -0.9   0.1      0.38   1.7e+03      14      26 ..     121     133 ..     115     142 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 6.8e-05
       AP3D1  20 PhYLkssatsss.kksassaqnseeveeipvaeldlsvplkvpglkrsdkyleeeesrkakkkakeekkkkkkkkkkkkkkkkkkkkkk 107
                 P YL++sa+s+s +  + + ++ e+v+ +     d ++   v++   +d+ +++  ++ + +++ ee   +++k    + +kk kk k+
  EEA22540.1  30 PGYLRQSANSNSrAPIPREVEKTESVSTASLIDVDAPSVQSVHS-DFLDQEVKRTTQAGRIEREAEEAALAREKAAAASSSKKGKKSKA 117
                 89*****9887432222222222333333333333333335555.56777777744443333333333333333333333322111111 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.38
       AP3D1  14 leqenNPhYLkss 26 
                  + + NP YL ++
  EEA22540.1 121 CKNAENPVYLGNA 133
                 56789*****986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (191 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1116  (0.0622455); expected 358.6 (0.02)
Passed bias filter:                      630  (0.0351386); expected 358.6 (0.02)
Passed Vit filter:                        58  (0.00323498); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.46u 0.29s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 1308.26
//
Query:       EEA22541.1  [L=250]
Description: v-SNARE protein Bos1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.9e-13   48.9   1.2    1.3e-12   47.8   1.2    1.6  1  V-SNARE_C   Snare region anchored in the vesicle membrane C-t
     0.0017   18.2   0.0     0.0037   17.1   0.0    1.6  1  Sec20       Sec20
  ------ inclusion threshold ------
      0.031   13.8   0.2      0.069   12.7   0.2    1.6  1  Sigma70_r4  Sigma-70, region 4


Domain annotation for each model (and alignments):
>> V-SNARE_C  Snare region anchored in the vesicle membrane C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.8   1.2   2.1e-16   1.3e-12       4      65 ..     161     222 ..     158     223 .. 0.94

  Alignments for each domain:
  == domain 1  score: 47.8 bits;  conditional E-value: 2.1e-16
   V-SNARE_C   4 lresdrlknShrivdetisiGaailedLhsQretLkrarsklhnvanrlgksnsiLrsikrR 65 
                 lre++   + ++++de++ +G a+l+dL++Qr+ Lk+++++l  v+n+lg+s  ++r+++rR
  EEA22541.1 161 LREQSFFAQTNTQLDEFLDRGRAVLQDLGQQRDILKNTQRRLYSVGNTLGISGDTIRRVERR 222
                 677777888899*************************************************9 PP

>> Sec20  Sec20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   0.0   6.2e-07    0.0037      13      85 ..     170     243 ..     164     249 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 6.2e-07
       Sec20  13 isqllsqevqqSeenleeldastkslekleeeykqvedvlsrskklvkklerrdktdkllvflalg.lflacvv 85 
                  + +l +  ++    l++l ++   l++++  + +v ++l  s + ++ +err + dk +   ++  +fl+c +
  EEA22541.1 170 TNTQLDEFLDRGRAVLQDLGQQRDILKNTQRRLYSVGNTLGISGDTIRRVERRAREDKWIFWGGVVvFFLFCWL 243
                 677888889999999********************************************999987526677643 PP

>> Sigma70_r4  Sigma-70, region 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.2   1.1e-05     0.069      25      46 ..     204     225 ..     189     226 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 1.1e-05
                 HHHHHHTS-HHHHHHHHHHHHH CS
  Sigma70_r4  25 EIgerlgiSrerVrqiekrAlr 46 
                  +g++lgiS  ++r+ e+rA++
  EEA22541.1 204 SVGNTLGISGDTIRRVERRARE 225
                 59******************75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (250 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       945  (0.0527079); expected 358.6 (0.02)
Passed bias filter:                      667  (0.0372023); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.30s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 1705.87
//
Query:       EEA22542.1  [L=340]
Description: malate dehydrogenase, NAD-dependent [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.6e-48  163.0   0.0    1.5e-47  161.6   0.0    1.7  2  Ldh_1_C        lactate/malate dehydrogenase, alpha/beta C-ter
    5.3e-45  153.0   0.1    1.9e-44  151.2   0.0    1.9  2  Ldh_1_N        lactate/malate dehydrogenase, NAD binding doma
     0.0028   16.7   0.0      0.004   16.2   0.0    1.3  1  3Beta_HSD      3-beta hydroxysteroid dehydrogenase/isomerase 
  ------ inclusion threshold ------
      0.012   14.9   0.0       0.14   11.5   0.0    2.5  2  THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase,
      0.093   12.3   0.1        3.4    7.2   0.1    2.3  2  Glyco_hydro_4  Family 4 glycosyl hydrolase


Domain annotation for each model (and alignments):
>> Ldh_1_C  lactate/malate dehydrogenase, alpha/beta C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0      0.99   3.6e+03      21      41 ..      22      41 ..      12      53 .. 0.70
   2 !  161.6   0.0   4.2e-51   1.5e-47       1     167 []     170     336 ..     170     336 .. 0.97

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.99
                GGEE--EEBSSSTETTEEHHH CS
     Ldh_1_C 21 rsvkvtViGgHsgvtiiplls 41
                + +kvtV+G  +g++ +pl+ 
  EEA22542.1 22 QASKVTVLGAAGGIG-QPLSL 41
                556999999999876.66644 PP

  == domain 2  score: 161.6 bits;  conditional E-value: 4.2e-51
                 THHHHHHHHHHHHHHHTS-GGGEE--EEBSSSTETTEEHHHHHTTSTTSTHHHHHHHHHHHHHHHHHHHHHHTTSSSS-HHHHHHHHHHHHHHHTTHTE CS
     Ldh_1_C   1 TtLDivRaktflaekagvtprsvkvtViGgHsgvtiipllsqvkellklsekqleeliervqnggdevvkakkGagsatlsmAvAgakfveallrdtke 99 
                 TtLD+vRa+ f+++ + ++p++++v+V+GgHsgvti+pllsq+++  +++ +  ++l++r+q+ggdevvkak+GagsatlsmA+Aga+f+e+ll++ ++
  EEA22542.1 170 TTLDVVRASRFISQVKTTDPANEEVPVVGGHSGVTIVPLLSQSNH-ADIEGETRDALVNRIQFGGDEVVKAKDGAGSATLSMAFAGARFAESLLKAAQG 267
                 9********************************************.999************************************************** PP

                 EEEEEEEEESCCCE...CCSSEEEEEEEEEEETTEEEEE-------HHHHHHHHHHHHHHHHHHHHHHCCH CS
     Ldh_1_C 100 ilsagvyldgevgl...kdqeieyfsvPvvlgknGvekvleilklndfeeekleksvkeLkkeiekglefv 167
                 +  +gv+++  v++   kdq+i++f++ v lg +Gv+++l +++ n+ ee+ le++ + Lkk+i+kg++fv
  EEA22542.1 268 V--QGVIEPTFVDSplyKDQGIDFFASRVELGPDGVKEILPVGQVNAYEEKLLEACLADLKKNIKKGVDFV 336
                 *..********997333577***********************************************9985 PP

>> Ldh_1_N  lactate/malate dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  151.2   0.0   5.3e-48   1.9e-44       2     141 .]      25     168 ..      24     168 .. 0.98
   2 ?   -1.4   0.0      0.64   2.3e+03      83      93 ..     218     228 ..     209     230 .. 0.86

  Alignments for each domain:
  == domain 1  score: 151.2 bits;  conditional E-value: 5.3e-48
                 EEEEETTTSHHHHHHHHHHHHTTSSSEEEEE-SSHHHHHHHHHHHHHCHCCSTS-EEEEE..SSGGGGTTESEEEE--S-SS-TTTTHHHHHHHHHHHH CS
     Ldh_1_N   2 kvavvGaaGgiGqslalllankkladelaLlDiakekleGvaldlshistflsvkvkvse..keeealkdadvvvitagvprkpGetRddLlkvNakIv 98 
                 kv+v+GaaGgiGq+l+ll++ ++ +++laL+Di+    +Gva+dlshi+t+++v ++ +   +  ealkda++v+i+agvprkpG+tRddL+++Na+Iv
  EEA22542.1  25 KVTVLGAAGGIGQPLSLLMKLNPRVSQLALYDIR--GGPGVAADLSHINTNSTVTGYDPTpsGLSEALKDAEIVLIPAGVPRKPGMTRDDLFNTNASIV 121
                 9*********************99999*******..99******************9988789************************************ PP

                 HHHHHHHHHHTTTSEEEE-SSSHH....HHHHHHHHHHTS-GGGEEE CS
     Ldh_1_N  99 keiveaiakvapnaivlvvsNPvd....iltevlkkasglpkkrvig 141
                 +++++a a+ apna++lv+sNPv+    i++ev+k ++ +++kr++g
  EEA22542.1 122 RDLAKATADAAPNAKILVISNPVNstvpIVAEVFKSKGVYNPKRLFG 168
                 *********************************************98 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.64
                 TTTTHHHHHHH CS
     Ldh_1_N  83 pGetRddLlkv 93 
                 +GetRd L+++
  EEA22542.1 218 EGETRDALVNR 228
                 8*******985 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   1.1e-06     0.004       2      92 ..      28     117 ..      27     164 .. 0.86

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.1e-06
   3Beta_HSD   2 vtGgaGFlGralvkeLvrlee.lkevrvlDlrespelleelskvnvkkviegDvtdkdkleealegvdvvihlaslvdvagkltedeimkvn 92 
                 v+G+aG +G+ l + L++l++ + ++  +D+r +p +  +ls++n++++++g     + l+eal+++++v+  a++    g++++d + + n
  EEA22542.1  28 VLGAAGGIGQPL-SLLMKLNPrVSQLALYDIRGGPGVAADLSHINTNSTVTGYDPTPSGLSEALKDAEIVLIPAGVPRKPGMTRDD-LFNTN 117
                 99********98.678888887**************************999988999******************99999977766.55555 PP

>> THF_DHG_CYH_C  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   3.9e-05      0.14      35     103 ..      22     119 ..      15     128 .. 0.76
   2 ?   -1.1   0.0      0.28     1e+03     130     151 ..     190     211 ..     180     216 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 3.9e-05
                    TT-EEEEE---TTTHHHHHHHHHC............T..............T-EEEEE-TTSCCHHHHHCCSSEEEE-SS-T...T-B-GGGS-TT CS
  THF_DHG_CYH_C  35 egkkvvvvGrsnivgkplallLle............k..............natVtvchsktkdlaeitreadivvvavGkp...elikaemvkeg 101
                    +  kv+v+G+   +g+pl+ll++             +              n+tVt  +   + l+e ++ a+iv + +G+p   ++ + + ++++
     EEA22542.1  22 QASKVTVLGAAGGIGQPLSLLMKLnprvsqlalydiRggpgvaadlshintNSTVTGYDPTPSGLSEALKDAEIVLIPAGVPrkpGMTRDDLFNTN 117
                    56799***************9998555555555555055555556666667**************************9997611156666666666 PP

                    -E CS
  THF_DHG_CYH_C 102 av 103
                    a 
     EEA22542.1 118 AS 119
                    55 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.28
                    SSEE--TTTSCHHHHHHHHHHH CS
  THF_DHG_CYH_C 130 asaitPvpgGVGpmTvamllkn 151
                    a+   Pv gG + +T++ ll++
     EEA22542.1 190 ANEEVPVVGGHSGVTIVPLLSQ 211
                    5555799999999999999876 PP

>> Glyco_hydro_4  Family 4 glycosyl hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0     0.025        89      28      86 ..      49     105 ..      25     114 .. 0.60
   2 ?    7.2   0.1   0.00095       3.4     123     159 ..     120     156 ..     114     171 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.025
                    EEEEEEE-SSHHHHHHHHHHHHHHHHHCTTTCEEEEESSHHHHHTT-SEEEE---TTHH CS
  Glyco_hydro_4  28 vselaLvDideerldaiqtlakklveeagadlkieattdrkealkdadfVitairvGle 86 
                    vs+laL+Di       ++  +++++ +  +     + + + ealkda++V++ + v  +
     EEA22542.1  49 VSQLALYDIRG--GPGVAADLSHINTNSTVTGYDPTPSGLSEALKDAEIVLIPAGVPRK 105
                    56678888876..2333333444444444444444567789999999999987776655 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.00095
                    HHHHHHHHHHHH-TTSEEEE-SSSHHHHHHHHHHHST CS
  Glyco_hydro_4 123 vlleIakdieelcPdawvlnytNPaavvteallrlvp 159
                    ++ ++ak+  + +P+a +l  +NP+  +  ++  ++ 
     EEA22542.1 120 IVRDLAKATADAAPNAKILVISNPVNSTVPIVAEVFK 156
                    678999*******************988877776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (340 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       261  (0.0145574); expected 358.6 (0.02)
Passed bias filter:                      233  (0.0129957); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2355.86
//
Query:       EEA22543.1  [L=954]
Description: AAA family ATPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-16   61.1   0.0    4.3e-16   59.5   0.0    1.9  1  AAA           ATPase family associated with various cellular 
    0.00032   20.7   0.0      0.001   19.1   0.0    1.8  1  AAA_5         AAA domain (dynein-related subfamily)
     0.0011   19.3   0.6      0.012   15.9   0.1    2.6  2  AAA_22        AAA domain
     0.0033   17.8   2.6     0.0094   16.3   0.1    2.9  3  AAA_16        AAA ATPase domain
     0.0096   14.5  30.8      0.015   13.9  30.8    1.3  1  Macoilin      Macoilin family
  ------ inclusion threshold ------
      0.025   14.3   0.0      0.025   14.3   0.0    2.4  3  AAA_30        AAA domain
      0.031   14.6   0.0        0.1   13.0   0.0    1.9  1  AAA_19        AAA domain
      0.039   13.7   0.0      0.039   13.7   0.0    3.7  2  AAA_11        AAA domain
       0.14   10.5   3.0       0.48    8.8   2.5    2.0  1  Mem_trans     Membrane transport protein


Domain annotation for each model (and alignments):
>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.5   0.0   2.2e-19   4.3e-16       2     127 ..     737     852 ..     736     856 .. 0.92

  Alignments for each domain:
  == domain 1  score: 59.5 bits;  conditional E-value: 2.2e-19
                 EEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTSS CS
         AAA   2 llyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksrsgseseeeervvnqLlteldgvkkke 100
                 +l+GppGtGKTl+a+ +a+ l+++++ +s+ el        e +++++++ a +     +l++DE+d + ++r + ++ +++ +v+ +l+ l+ ++   
  EEA22543.1 737 VLHGPPGTGKTLTAEGIAELLKRPLYMVSAGELG-TDSRSLEGELNKILDIAHSWG--AVLLLDEADVFLEKR-TIQDIHRNALVSIFLRLLEYFQG-- 829
                 69********************************.456888999*****9998877..***************.77999999*************99.. PP

                 STEEEEEEESSGGGSTHHHHSTTSSEE CS
         AAA 101 skvivigatnrpdkldpallrgRfdrk 127
                    i+ ++tnr++++d+a+  +R+ + 
  EEA22543.1 830 ---ILFLTTNRVETFDDAFQ-SRIHIA 852
                 ...99***************.998765 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   5.1e-07     0.001       3      46 ..     737     781 ..     736     813 .. 0.77

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 5.1e-07
                 EEE--SSSSHHHHHHHGGGGBS--EEEEE.--TT--HHHHH--B- CS
       AAA_5   3 lLvGppGtgKselaerlaaalnreveyvq.ltrdtteedlkgrre 46 
                 +L GppGtgK+  ae +a++l+r++ +v  +  +t ++ l g+++
  EEA22543.1 737 VLHGPPGTGKTLTAEGIAELLKRPLYMVSaGELGTDSRSLEGELN 781
                 699*********************999861455777888888777 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.1     6e-06     0.012       6      64 ..     734     784 ..     729     789 .. 0.78
   2 ?    1.3   0.1       0.2   3.9e+02      80     112 ..     781     811 ..     763     831 .. 0.65

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 6e-06
      AAA_22   6 gilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsst.sskdllrellral 64 
                  + v++G++GtGKT++++ ++e l         +++++ v + +++ +s++l  el ++l
  EEA22543.1 734 LVAVLHGPPGTGKTLTAEGIAELL---------KRPLYMVSAGELGtDSRSLEGELNKIL 784
                 5789******************99.........777777777777766776666666655 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.2
      AAA_22  80 ealeqalraravielliiDEaqh.lrseealeeL 112
                 +++ + +++ ++  +l++DEa+  l +++ ++++
  EEA22543.1 781 NKILDIAHSWGA--VLLLDEADVfL-EKRTIQDI 811
                 445555555555..********955.54444444 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.3       4.4   8.8e+03     106     128 ..     165     205 ..     129     212 .. 0.58
   2 ?   -0.9   0.0      0.93   1.9e+03      52     109 ..     616     664 ..     606     687 .. 0.78
   3 !   16.3   0.1   4.7e-06    0.0094      17      52 ..     724     791 ..     718     901 .. 0.60

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 4.4
      AAA_16 106 a..................avpelagaeasrllellkrlla 128
                 +                  +++e+a a+ +++ e+l+r+++
  EEA22543.1 165 KkkrrhrhneessdsestsSSDEDALADQKAMKEKLARMVK 205
                 13333333333344555455555555666888888888874 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.93
      AAA_16  52 ggiflrgkcdqlesaipysalaqalareellrqlldeaesaeleawrekleealaavp 109
                 ++++++ ++d++          + ++++e ++ l++++++++ e+ +e+ ee+l +++
  EEA22543.1 616 KAHVVQVEYDEN---------GNEITKKEDFELLDNDKDEKDGEPSPEFTEEELLIAS 664
                 377788888888.........455678899*******999999999999999987554 PP

  == domain 3  score: 16.3 bits;  conditional E-value: 4.7e-06
      AAA_16  17 ervrsgrp..elvllsGesGvGKsslvrellralekd..............................g 52 
                 ++v +g +   + +l+G++G+GK+  ++ +++ l++                               g
  EEA22543.1 724 DDVIQGKGkgLVAVLHGPPGTGKTLTAEGIAELLKRPlymvsagelgtdsrslegelnkildiahswG 791
                 55666666668999*****************8777776666666666655555555555555555553 PP

>> Macoilin  Macoilin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9  30.8   7.5e-06     0.015     203     385 ..      16     216 ..       9     381 .. 0.57

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 7.5e-06
    Macoilin 203 Pkeqqlldkeereaeeqlaaakelvevdpvalsknnhslnkkdsslklpeleyrekkksakssrsdskkkhehn......esvdsklqekeymenksks 295
                 P+++q  + +e+++  +++++  ++ v+++++s  ++ l + +++++  ++ + ++ k++++s++ ++k+h++        s++sk++++  +e+ s++
  EEA22543.1  16 PQQHQQPESQEENTPSEATTSSTVA-VSSNVTSTTGKPLLEPTATTSKENVAKASEVKAKTDSKKPKSKSHKQRtatkkaLSKKSKKKKHAKVESSSEE 113
                 3333333333333333333333333.5555555555444443444444444444444444444444333333333444333344444444455666666 PP

    Macoilin 296 krlsksessg.sesellveesvkskssssssssn...knskkasagsagssnssskkhsessksvtsssssknskkq........klp.aGkssaalkd 381
                 +++s+ses++ s+se + +esv+s s+ss+ +s+   +  k+++a++a+  +   ++ +++++s ++s+ss++++          kl+ + k++++ ++
  EEA22543.1 114 EEISTSESESsSSSESKESESVDSDSESSEIESEsdrHRRKRNKAKKAKKLKKKRRHRHNEESSDSESTSSSDEDALadqkamkeKLArMVKKQRKARK 212
                 666655544304445555566666555554444433322233333333333333222222233333333333322112222222222101222223333 PP

    Macoilin 382 aaen 385
                 +a++
  EEA22543.1 213 MAKK 216
                 3333 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   1.0       4.2   8.4e+03     145     179 ..     158     191 ..     152     207 .. 0.67
   2 ?   -3.4   0.0       3.4   6.8e+03     142     175 ..     346     379 ..     336     390 .. 0.67
   3 ?   14.3   0.0   1.3e-05     0.025      17      44 ..     732     759 ..     721     802 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 4.2
      AAA_30 145 gigtaeLtevvRqkeseeraaalalregdaeeale 179
                 + ++ +L++ +R +++ee + ++  ++ d++ al+
  EEA22543.1 158 AKKAKKLKKKRRHRHNEESSDSESTSSSDED-ALA 191
                 5567788888888887777777777776666.333 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 3.4
      AAA_30 142 eaagigtaeLtevvRqkeseeraaalalregdae 175
                 e+++ +   L++vv+ ++++ ++   al+  + +
  EEA22543.1 346 EETRDHMKALKKVVKTEKKKKARKLAALKVAHLK 379
                 4566777888888888776666666666666655 PP

  == domain 3  score: 14.3 bits;  conditional E-value: 1.3e-05
      AAA_30  17 gdrvavltGpAGtGKttalkalreawea 44 
                 + +vavl+Gp+GtGKt + ++++e++++
  EEA22543.1 732 KGLVAVLHGPPGTGKTLTAEGIAELLKR 759
                 45799******************99875 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0     5e-05       0.1      10      78 ..     733     871 ..     724     934 .. 0.62

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 5e-05
      AAA_19  10 ekvllvtaGpGtGKTrvlkhivallvelggvkp...............eeillvaftgrAakelrerlaalgae.atTiHrlal............... 77 
                   v ++ ++pGtGKT + ++i +ll++   +                 ++il +a    A+  l e+   l+++ ++ iHr al               
  EEA22543.1 733 GLVAVLHGPPGTGKTLTAEGIAELLKRPLYMVSagelgtdsrslegelNKILDIAHSWGAVLLLDEADVFLEKRtIQDIHRNALvsiflrlleyfqgil 831
                 5578999****************9998765433466666666666666666666666666666666553332224556666665666666666666666 PP

      AAA_19  78 .......................................l 78 
                                                        l
  EEA22543.1 832 flttnrvetfddafqsrihialrygdlttkakrsvwkmfL 871
                 6666666666666666666665555555555555555550 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?  -31.2  49.4         9   1.8e+04     102     178 ..      84     165 ..       5     271 .. 0.60
   2 ?   13.7   0.0     2e-05     0.039      16      41 ..     729     757 ..     703     796 .. 0.65

  Alignments for each domain:
  == domain 1  score: -31.2 bits;  conditional E-value: 9
      AAA_11 102 eavksvsleekvekrlekee.....kaqlakeiskeleklakelrafeeeeek.................eklkkskekskskleqerrklkkerkels 178
                 ++ ++  +++ ++k+++k++     + +  +eis ++ + +           +                 e       +s+s++++++r+  k++k+l+
  EEA22543.1  84 SHKQRTATKKALSKKSKKKKhakveSSSEEEEISTSESESS-----------SsseskesesvdsdsessE------IESESDRHRRKRNKAKKAKKLK 165
                 22222222222222222222222221111222222222222...........1222222333332222221......2222222222222222222222 PP

  == domain 2  score: 13.7 bits;  conditional E-value: 2e-05
      AAA_11  16 ese...itliqGPPGtgKTktivellsql 41 
                  ++   +++++GPPGtgKT t  ++ + l
  EEA22543.1 729 GKGkglVAVLHGPPGTGKTLTAEGIAELL 757
                 444566899**********6655555444 PP

>> Mem_trans  Membrane transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   2.5   0.00024      0.48     159     251 ..      63     420 ..      33     422 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.00024
   Mem_trans 159 fpdtaasivsikvdsdvvsldgrk.pleteaeikedg..klhvtvrksnasrsdivssstprpsnltnaeiyslq........................ 230
                 ++++ as+v++k ds++ +++++k    t ++  +++  k h +v +s+++ ++i+ s++++ s   + e +s++                        
  EEA22543.1  63 ENVAKASEVKAKTDSKKPKSKSHKqRTATKKALSKKSkkKKHAKVESSSEE-EEISTSESESSSSSESKESESVDsdsesseiesesdrhrrkrnkakk 160
                 446777888888888888888888655565554433300333333333333.33333445555555555555555555556666666777777777777 PP

   Mem_trans 231 ................................................................................................... 230
                                                                                                                    
  EEA22543.1 161 akklkkkrrhrhneessdsestsssdedaladqkamkeklarmvkkqrkarkmakkylsdeedqedggnrrrlklkegkgekgkrgkskraskvafkrv 259
                 777778888888888888888888888888888887788888888888888888888888888888888888888888888888888888888888888 PP

   Mem_trans 231 ................................................................................................... 230
                                                                                                                    
  EEA22543.1 260 delwdstihnfklretlddpdadefdqyifnvrrkfdwenkyvdtwvdikskplrealstvmdgvkgvslvaetpvidpnmlflyleetrdhmkalkkv 358
                 888888888888888888888888888888888888888888888888888888888877777777777777777777777777777777777777777 PP

   Mem_trans 231 .........................................mtrlilimvlrklirnPntys 251
                                                             ++ ++ l+ ++++Pnt++
  EEA22543.1 359 vktekkkkarklaalkvahlkvlikyldtdyaetkktlyplLESNMITFDLLWALFKPNTIA 420
                 77777777777777777777777777777777777777776556666667777777777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (954 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3014  (0.168108); expected 358.6 (0.02)
Passed bias filter:                      714  (0.0398237); expected 358.6 (0.02)
Passed Vit filter:                       336  (0.0187406); expected 17.9 (0.001)
Passed Fwd filter:                        97  (0.00541023); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 2.17u 0.41s 00:00:02.58 Elapsed: 00:00:00.68
# Mc/sec: 4250.53
//
Query:       EEA22544.1  [L=540]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.3e-09   35.5   0.1    1.4e-08   34.1   0.0    1.7  2  Fungal_trans    Fungal specific transcription factor domain
    6.5e-05   23.0   8.1    6.5e-05   23.0   8.1    1.7  2  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
       0.28   11.4   1.9       0.71   10.1   0.2    2.5  3  DDE_Tnp_IS66_C  IS66 C-terminal element
        2.7    8.4   6.9       0.43   10.9   2.5    2.0  2  zf-C6H2         zf-MYND-like zinc finger, mRNA-binding


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.1   0.0   3.2e-12   1.4e-08       1     196 [.      88     274 ..      88     308 .. 0.82
   2 ?   -1.8   0.0      0.27   1.2e+03     210     248 ..     434     471 ..     416     485 .. 0.74

  Alignments for each domain:
  == domain 1  score: 34.1 bits;  conditional E-value: 3.2e-12
  Fungal_trans   1 ldrffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeili......hedfsspsssl 91 
                   +d ff+ ++p    +h+++f +   ++++ +    s + l a++a+ al  ++ +  ++ s  ++  + +        ++      ++d + +++ +
    EEA22544.1  88 IDNFFEAVYPVAITIHEQTFRDRW-NTGKMPDSRGSYARLMAMCAVSALRIKNGAVLKERSVPNDLNPRL--------YFdetlqaLPDNVNEFEEF 175
                   577888888888888888888888.777777777788888888888888888887777555555552222........222222455688888888* PP

  Fungal_trans  92 wilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcd 188
                   ++lq++ l++l  + +sd +l   ++g+   ++ + g+++++ +        l+e +ae+rrRl+w  + l+++++l+ G+ +  ++ q ++++P  
    EEA22544.1 176 ESLQATGLACLTALHYSDGPLLHQILGLYHAVVAEQGFGDEKRWPRG-----LSEIDAEERRRLFWHMYRLEVHTSLVIGHVVRCPELQSSVAYPTI 267
                   *****************************99********99999997.....88888************************9955999999999988 PP

  Fungal_trans 189 dddlwesd 196
                   +d ++++d
    EEA22544.1 268 QD-IDSMD 274
                   88.76665 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 0.27
  Fungal_trans 210 neeksrkiasfllaLkkilskiagsllsiekqlqqrdlq 248
                   ne  s++ ++ l +++  +s+++  +ls ++ +  +  q
    EEA22544.1 434 NEGLSKSDYYHLRTVMLCMSELLE-ILSSCMASATEAGQ 471
                   677788889999999999999999.88888877766555 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.0   8.1   1.4e-08   6.5e-05       1      38 [.      17      57 ..      17      59 .. 0.87
   2 ?   -3.5   0.1       2.8   1.3e+04      25      33 ..     366     373 ..     360     375 .. 0.72

  Alignments for each domain:
  == domain 1  score: 23.0 bits;  conditional E-value: 1.4e-08
                SS-HHHHHCT---STSSSS...-HHHHHCTHHHCCCCTCCC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPa...CsnCkklnleCtfysessk 38
                +aCd C+k+ ++C +++++   C+ C+  ++ Ct  + + k
  EEA22544.1 17 RACDFCHKRGRRCKKDTESplqCTTCIDFGVACTWSRVPAK 57
                69*************8888889************6666655 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 2.8
                 HCTHHHCCC CS
     Zn_clus  25 klnleCtfy 33 
                 + n  Ct y
  EEA22544.1 366 TANIACT-Y 373
                 5678888.6 PP

>> DDE_Tnp_IS66_C  IS66 C-terminal element
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.2   0.00016      0.71       9      35 ..     150     174 ..     149     176 .. 0.91
   2 ?   -3.4   0.1       2.6   1.2e+04      30      37 ..     477     484 ..     472     484 .. 0.81
   3 ?   -1.3   0.0       0.6   2.7e+03      19      29 ..     522     530 ..     522     535 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00016
  DDE_Tnp_IS66_C   9 NgvdPyaYLkdvLerlpdahpaedlee 35 
                     N+++P+ Y+  +L+ lpd  +++++ee
      EEA22544.1 150 NDLNPRLYFDETLQALPD--NVNEFEE 174
                     9****************8..7888887 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 2.6
  DDE_Tnp_IS66_C  30 aedleeLL 37 
                     +ed+++LL
      EEA22544.1 477 VEDIDRLL 484
                     68999998 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.6
  DDE_Tnp_IS66_C  19 dvLerlpdahp 29 
                     d+L+r+p  +p
      EEA22544.1 522 DILQRIP--WP 530
                     79*****..54 PP

>> zf-C6H2  zf-MYND-like zinc finger, mRNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9   2.5   9.7e-05      0.43       3      24 ..      26      48 ..      22      51 .. 0.87
   2 ?   -3.9   0.1         4   1.8e+04       4      15 ..     360     371 ..     359     372 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 9.7e-05
     zf-C6H2  3 sseCgkeass.LqCptClklgik 24
                + +C+k+++s LqC tC+  g+ 
  EEA22544.1 26 GRRCKKDTESpLQCTTCIDFGVA 48
                568******9********99875 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 4
     zf-C6H2   4 seCgkeassLqC 15 
                 ++Cg ++ ++ C
  EEA22544.1 360 NRCGYQTANIAC 371
                 579999988998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (540 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       694  (0.0387082); expected 358.6 (0.02)
Passed bias filter:                      559  (0.0311785); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.48
# Mc/sec: 3369.02
//
Query:       EEA22545.1  [L=356]
Description: isopenicillin N synthetase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-30  106.7   0.0      2e-30  106.0   0.0    1.3  1  DIOX_N        non-haem dioxygenase in morphine synthesis N-te
    2.6e-16   60.0   0.0      1e-15   58.0   0.0    1.9  2  2OG-FeII_Oxy  2OG-Fe(II) oxygenase superfamily
  ------ inclusion threshold ------
      0.067   13.5   0.4       0.58   10.4   0.1    2.4  3  OKR_DC_1_N    Orn/Lys/Arg decarboxylase, N-terminal domain
       0.17   11.6   0.1       0.34   10.7   0.1    1.5  1  GP40          Glycoprotein GP40 of Cryptosporidium


Domain annotation for each model (and alignments):
>> DIOX_N  non-haem dioxygenase in morphine synthesis N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.0   0.0   4.4e-34     2e-30       1     117 [.      36     159 ..      36     160 .. 0.92

  Alignments for each domain:
  == domain 1  score: 106.0 bits;  conditional E-value: 4.4e-34
      DIOX_N   1 iPvidlspl.sdd.edraavaeqlreAcrevGffyvvnhgvpeelidelfeaareFFalPeeeKekl...akspsfrGysrlgeektdg.kkldwkesf 93 
                 iP+id+s++ s d +dr+a+ae++reA++++Gff+ +nhg++ +l+++++e+areFFalPee+K+++     +++++Gy+++ + + +g k +d+ e+f
  EEA22545.1  36 IPIIDVSRMhSPDiADRQALAEEIREAAHSIGFFCMTNHGIDMNLASNVMEQAREFFALPEEKKMEVsseLIPDEYCGYHGMYRYNPNGwKYRDLYEAF 134
                 9********96667*****************************************************5433357************************* PP

      DIOX_N  94 dlgtelpeddp..agkplegpnqwPe 117
                 +++++ p++dp   + ++ + n+wP+
  EEA22545.1 135 NWNYN-PAKDPeyPDPSTPQINLWPK 159
                 *****.6666767778899******8 PP

>> 2OG-FeII_Oxy  2OG-Fe(II) oxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0      0.94   4.2e+03      51      74 ..       6      29 ..       2      44 .. 0.74
   2 !   58.0   0.0   2.3e-19     1e-15       6      98 ..     210     301 ..     204     303 .. 0.82

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.94
                  EE----TTEEEEEE-HHHHHHTTS CS
  2OG-FeII_Oxy 51 lrvppvdnslivniGdallflsng 74
                  ++ +  ++++++ +G  + f+sn 
    EEA22545.1  6 TSTNNTPKTIRLTNGKDFTFVSNA 29
                  556667788999999999998886 PP

  == domain 2  score: 58.0 bits;  conditional E-value: 2.3e-19
                   EEEEE-S-...--------EEEEEESSSEEEEEEE-TT---EE.EETEEEE----TTEEEEEE-HHHHHHTTS-S----EEE----GTGSEEEEEEE CS
  2OG-FeII_Oxy   6 vlnyypph...pdpevilglgahtdaslltillqddvgglevf.kdgkwlrvppvdnslivniGdallflsngryksvlHrVlpvnegerRvsiayf 98 
                   +l+y p +    d     g+gahtd +++ti+ +d  +glev+ k+g+w++v+p +++++vni d ++  +n ++ s+ HrV ++   ++R+s+ +f
    EEA22545.1 210 ILHY-PQQeacRDEQ--NGIGAHTDVEFFTIITSDA-EGLEVLsKSGRWIKVKPIPGCFVVNIADCFMRQTNDFFVSTVHRVINESD-RERYSLPFF 301
                   4555.4443326665..79***********999999.99*9*856688**********************************84333.44*****99 PP

>> OKR_DC_1_N  Orn/Lys/Arg decarboxylase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.1   0.00013      0.58      43     103 ..      38     105 ..       9     109 .. 0.84
   2 ?   -2.6   0.0       1.4   6.5e+03      32     104 ..     178     201 ..     170     203 .. 0.49
   3 ?   -0.2   0.0      0.26   1.2e+03      40      74 ..     262     308 ..     246     317 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00013
  OKR_DC_1_N  43 vlsvd.......deaaelldeirernedlPvFllaetrtsedvpadvlreidgfielledtpefiarq 103
                 +++v+        ++++l +eire    +  F +++   + ++  +v++++ +f+ l e+++ +++++
  EEA22545.1  38 IIDVSrmhspdiADRQALAEEIREAAHSIGFFCMTNHGIDMNLASNVMEQAREFFALPEEKKMEVSSE 105
                 5555566777778899********************99*******************99988877766 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.4
  OKR_DC_1_N  32 vieqnsriaavvlsvddeaaelldeirernedlPvFllaetrtsedvpadvlreidgfielledtpefiarqi 104
                 +++  +ri a+ l                                                   +++f+  +i
  EEA22545.1 178 FARRLTRIFALALH-------------------------------------------------VSEDFYDEHI 201
                 44444444444444.................................................4444554444 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 0.26
  OKR_DC_1_N  40 aavvlsvd............deaaelldeirernedlPvFllaetrt 74 
                 +++v++++                 +++e ++  + lP F  ++++t
  EEA22545.1 262 GCFVVNIAdcfmrqtndffvSTVHRVINESDRERYSLPFFWGIDRKT 308
                 68888888888888888888788889999999999999998777664 PP

>> GP40  Glycoprotein GP40 of Cryptosporidium
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.1   7.6e-05      0.34      55     128 ..       4      82 ..       1     100 [. 0.68

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 7.6e-05
        GP40  55 tfeksdntvk.ik.vngqdfstlsans....ssptenggsagqassrsrrslseetseaaatvdlfaftldggkrievav 128
                 t+  ++nt k i+  ng+df+ +s  +    s p  +           r++l+ee  eaa ++ +f++t  g   +++a 
  EEA22545.1   4 TVTSTNNTPKtIRlTNGKDFTFVSNAAtteeSIPIIDVSRMHSPDIADRQALAEEIREAAHSIGFFCMTNHG-IDMNLAS 82 
                 4555566655233269****9887543111155666666666667789*******************99765.4455555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (356 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       398  (0.0221987); expected 358.6 (0.02)
Passed bias filter:                      350  (0.0195214); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.48u 0.22s 00:00:00.70 Elapsed: 00:00:00.39
# Mc/sec: 2712.98
//
Query:       EEA22546.1  [L=564]
Description: uracil permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.8e-81  272.3  39.0    7.7e-81  272.1  39.0    1.0  1  Transp_cyt_pur  Permease for cytosine/purines, uracil, thiami


Domain annotation for each model (and alignments):
>> Transp_cyt_pur  Permease for cytosine/purines, uracil, thiamine, allantoin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  272.1  39.0   4.3e-85   7.7e-81       1     440 []      36     504 ..      36     504 .. 0.94

  Alignments for each domain:
  == domain 1  score: 272.1 bits;  conditional E-value: 4.3e-85
  Transp_cyt_pur   1 pvpeeeRtwktlnlfsiWl.ganlnintwvigalglalgLnwwqsvlviivgnligaifvallglaGakyGlpfpilsRasfGirgsllplllrv 94 
                     p++ ++Rt ++++++++W+   ++ni  w++g++++a+gLn wq++l++++gn++++i+ +++g+ Gak ++ fpi+ Ras G+ g ++ ++ rv
      EEA22546.1  36 PLETARRTFGPWEYATLWVvTGSFNIGGWTTGSSLIAYGLNVWQAMLTVVIGNIVVGILCVMTGAPGAKWHIGFPIIQRASWGVNGFVFVVIQRV 130
                     67889*************82569************************************************************************ PP

  Transp_cyt_pur  95 viaivwfgvqawiGsealllmlgkifgkwleigg..ailgtsltelvtffifwvvslvivllgvskirkffviaallvpvaafgfliwalvkaeg 187
                     ++ ++wf++q++ G++++ ++l  i++++ ++    a+  +++ ++ +f+if +++ +++   +++ ++ f i  ++v +  ++  iw +vka g
      EEA22546.1 131 FLGCIWFSTQVFWGGQCVKVVLTAIWPSFARVNKplANGTMTTGDFTSFIIFTLLYYPFIRIRPENYKRPFLISCVMVIPTIIVTWIWFMVKARG 225
                     ****************************88888888999******************************9999999999999************* PP

  Transp_cyt_pur 188 .Gpvldkavklg.kse........lflsavagvlagfatlilnapDFtryaktkkssvkiqlvavpllftlllligilvaaaakaay....gana 268
                      G ++   ++++  ++        +++ ++++ + + +  +   +D+trya++++   + ql++ p++ + ++ligi+ +++a+ ++    g+  
      EEA22546.1 226 vGILVTDVSSVSgVTQatgsylgwMMVLGIFTNINSMSVHVYVQSDYTRYARKPNDPDLAQLIVGPMGTMFVALIGIICTSCAAQLFpeqeGKLL 320
                     85444333333323336899***99999*******************************************************998423337789 PP

  Transp_cyt_pur 269 wspldilakfdet........agvllililvalaqlgvnisanllsagldlaallPkkinikrgsliaavialvivpwkllssssklftaflsll 355
                     w+p+++ a    +        a+v++  + + +aq g+ +++n + agldl+ l+P++ +i+rg++ +++i+ ++ pw ll+ +sk f++ l+ +
      EEA22546.1 321 WAPYELFAALQAHygnsshsrAAVAFGGLSFMIAQFGMVVANNGVGAGLDLSGLFPRYFTIRRGIVLMSIISFIVQPWALLNGASK-FLTVLGGY 414
                     ******9999999999**********************************************************************.******** PP

  Transp_cyt_pur 356 avflspvagviiadyfvvrrgylklaalytrr..rgsaYwyrkgvNwravaayivGiaaglvgvagsvg...ikvvkgaeklfdlsylvG 440
                     +vf++p++gv+  dyf +r+ +lkl +ly  +    ++Ywy+kg+Nwra++a+++G+ + l+g+   v     +  +g  +l+dlsyl+G
      EEA22546.1 415 GVFIGPMTGVMFSDYFLIRKQILKLSDLYNYNptGDGIYWYNKGYNWRALIAWMMGVWITLPGFVHRVRygsRSQWAGWSNLYDLSYLLG 504
                     ******************************99444579**************************999988888899999*********98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (564 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       559  (0.0311785); expected 358.6 (0.02)
Passed bias filter:                      261  (0.0145574); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 3642.67
//
Query:       EEA22547.1  [L=878]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.5e-50  169.7   1.6    6.9e-50  169.3   0.0    2.1  2  HbrB        HbrB-like
  ------ inclusion threshold ------
        1.1    9.1   6.2        2.8    7.7   6.2    1.7  1  Leader_Thr  Threonine leader peptide


Domain annotation for each model (and alignments):
>> HbrB  HbrB-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.6   0.4         2   1.8e+04     117     133 ..      24      41 ..      16      56 .. 0.39
   2 !  169.3   0.0   7.7e-54   6.9e-50       1     168 [.     503     664 ..     503     665 .. 0.93

  Alignments for each domain:
  == domain 1  score: -4.6 bits;  conditional E-value: 2
        HbrB 117 skekrsaspasqas.sss 133
                 +++++s++++sq+   +s
  EEA22547.1  24 QTQHQSPQRQSQNDrPGS 41 
                 333332333333322222 PP

  == domain 2  score: 169.3 bits;  conditional E-value: 7.7e-54
        HbrB   1 lladdaWqllcvrvlplFngedlrvpiEdlnklvelhiqlvierakalsllvedleeLlstglltLenkLsqleeerllkrLveiWkffytqvlpylea 99 
                 ++a+d+W++l++++l++F+g d+r+++Edlnklv +hiql++++   + ++vedl+eLl+tg++tL++++s++++e+l+++L++iW + ++++lp+++a
  EEA22547.1 503 MTAEDVWDFLKAKLLVIFDGGDVRIAVEDLNKLVVIHIQLCVQK--HMPTIVEDLRELLHTGFSTLNHSISGIPDEKLVPHLMQIWLLAFGTILPFIQA 599
                 6899****************************************..8999************************************************* PP

        HbrB 100 vfLPLetefklssllaeskekrsaspasqasssssstssssksserldvrrllLiaFRDsvvlPiyerl 168
                 vfLPL++efk+++++++ +e r+   a  ++    + s+ s+  ++ld+r+++L+aFRD+v+l +ye l
  EEA22547.1 600 VFLPLDLEFKGRGSVMNAREAREFWGALPTN----RDSEESSLGDELDIRMIVLTAFRDTVILQRYEGL 664
                 ********************88433333333....455678899**********************977 PP

>> Leader_Thr  Threonine leader peptide
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   6.2   0.00032       2.8      11      22 .]     211     223 ..     209     223 .. 0.89

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00032
  Leader_Thr  11 iTT.TiTTGnGAG 22 
                 iTT T TTG GAG
  EEA22547.1 211 ITTsTSTTGAGAG 223
                 6777********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (878 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       935  (0.0521501); expected 358.6 (0.02)
Passed bias filter:                      364  (0.0203023); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.72u 0.31s 00:00:01.03 Elapsed: 00:00:00.47
# Mc/sec: 5561.45
//
Query:       EEA22548.1  [L=103]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      5e-14   52.3   1.6    1.4e-13   50.8   0.1    1.9  2  Gon7      Gon7 family


Domain annotation for each model (and alignments):
>> Gon7  Gon7 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.1     0.024   4.4e+02       2      18 ..       9      25 ..       8      30 .. 0.83
   2 !   50.8   0.1   8.1e-18   1.4e-13      49     107 ..      33      93 ..      27      94 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.024
        Gon7  2 tAtYtapdieekefevd 18
                 A Y++p+ ++ +f+  
  EEA22548.1  9 SASYSSPQPPHTSFTFR 25
                699*****999999876 PP

  == domain 2  score: 50.8 bits;  conditional E-value: 8.1e-18
        Gon7  49 psepkkeadaelteLseLRaqltgLQddiNefLTermeeakkkkkkvdd..keeerieeei 107
                 pse+ +   a+ ++LseLR  +t +Q ++N fLTermee+kk +   ++   e+e+++ee+
  EEA22548.1  33 PSEKSDSVAAKKAYLSELRGLVTLVQAEVNVFLTERMEEDKKSAGGATGkdAEQEAKDEEN 93 
                 6777776679*******************************88777666556666677765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (103 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       656  (0.0365888); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.26s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 760.38
//
Query:       EEA22549.1  [L=878]
Description: vacuolar morphogenesis protein AvaB, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.1e-32  110.7   3.4    6.6e-31  106.8   0.0    3.8  4  Vps39_1   Vacuolar sorting protein 39 domain 1
    2.7e-18   66.6   0.0      1e-17   64.6   0.0    1.8  1  CNH       CNH domain
    1.3e-06   28.3   5.5    1.3e-05   25.1   2.8    3.1  3  Clathrin  Region in Clathrin and VPS
  ------ inclusion threshold ------
      0.076   13.3   0.4        3.2    8.2   0.0    3.4  3  PPR       PPR repeat
       0.14   11.4   0.1       0.26   10.4   0.1    1.4  1  ERO1      Endoplasmic Reticulum Oxidoreductin 1 (ERO1)
       0.36   11.8   1.8         24    6.1   0.3    3.7  3  TPR_14    Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> Vps39_1  Vacuolar sorting protein 39 domain 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       2.3     7e+03      28      53 ..      69      94 ..      64      98 .. 0.60
   2 ?   -2.1   0.1       1.6   4.7e+03      56      76 ..     393     413 ..     375     443 .. 0.49
   3 !  106.8   0.0   2.2e-34   6.6e-31       1     108 []     616     730 ..     616     730 .. 0.85
   4 ?    2.3   0.1     0.067     2e+02      19      67 ..     821     871 ..     810     878 .] 0.69

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 2.3
     Vps39_1 28 dlkdveeiLkkekkykeLidlYygkk 53
                + +++++  ++e  +++L+dl  +++
  EEA22549.1 69 AKDESQQQQQQEASTVNLVDLLREQE 94
                45555666666666666666666554 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.6
     Vps39_1  56 eeALeLlkelade...deedeeds 76 
                  eA+ Ll+ l d+   d   +++ 
  EEA22549.1 393 DEAISLLNMLEDAllkD---KAGR 413
                 56666666666664321...2222 PP

  == domain 3  score: 106.8 bits;  conditional E-value: 2.2e-34
     Vps39_1   1 iDTaLlkvYlktkpklvgpLlrleNaCdlkdveeiLkkekkykeLidlYygkklheeALeLlkelade.....deedeedsslkgeket.......iiq 87 
                 +DT+L+++ ++++p+l+g+L+r++N+Cd+++v e L+++ +  eLid+Yygkk+h++ALeLl ++ ++     +     ++ +++++         +i 
  EEA22549.1 616 VDTTLFRAHMYATPSLAGSLFRIANFCDPDVVMEKLEEHGRDTELIDFYYGKKMHRRALELLLKFGQAevkdeE-----EEEEENPTLAqlrgpkrTIA 709
                 8****************************************************************998554431.....222222222233444445** PP

     Vps39_1  88 ylqklseedldlileyskwvl 108
                 ylq+ls+e  dlile+++w+l
  EEA22549.1 710 YLQHLSPEYTDLILEFAEWPL 730
                 *******************97 PP

  == domain 4  score: 2.3 bits;  conditional E-value: 0.067
     Vps39_1  19 pLlrleNaCdlkdveeiL..kkekkykeLidlYygkklheeALeLlkelad 67 
                 ++l+ + +  + ++ + L  +  + y++  + + + ++h++ALe+ +   +
  EEA22549.1 821 EFLKSSSQYSPAKMLNLLprEDPNFYEARAIVFSKMGQHRQALEIYVFKLK 871
                 5566665566666666665556678888889999**********9764444 PP

>> CNH  CNH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.6   0.0   3.5e-21     1e-17      38     272 ..     101     348 ..      83     350 .. 0.82

  Alignments for each domain:
  == domain 1  score: 64.6 bits;  conditional E-value: 3.5e-21
         CNH  38 vtqlaVleelnlllllsdkqLyvydlsaLeekeeesqlakkksenltqklpetkgchffa.........irngyskekfLvvavkskivllewneplkk 127
                   qla ++e n+l++ls+ ++ ++dl++ e +e               +l +tkg+++fa           +  s   +L+vavk+ki+l +w++ ++ 
  EEA22549.1 101 AEQLAFIKEANILVVLSGGYVSLHDLQSYELQE---------------QLAKTKGASTFAvtsnvindvETDLPSIVSRLAVAVKRKILLWTWKD-MEL 183
                 68****************************999...............6777777777777666544434556677889***************9.555 PP

         CNH 128 fkkklrefqvpaevfsisvl.kpklcvgvakgFelvnldegaaeslldpedns..............ldfaarkenlkplaviqis............. 198
                    +++e+++ + + +++++ ++kl+vg  +++ lvn+++++ ++++ p +                +            ++  i              
  EEA22549.1 184 A-PDVTEITLVSGIKTLTWIsSTKLIVGLGSNYVLVNIETKELSDIVGPGSIGggpgqessrlggvgV-----------ASMSYIGmggmvpkplatrl 270
                 5.6899999999999999999******************99999999888877777543333333331...........44433335566666666665 PP

         CNH 199 .edefLlcydefavyvdlqGrrsrdseleWegkPesvaclepyllafhk...nfieirsvetgelvqeisgkklrfll 272
                  e+++Ll  d    + d  G+   + ++ W  +Pe+  +++pylla ++     +e+r+ +t  l+q+is++++ +l+
  EEA22549.1 271 sEGQVLLAKDINTHFIDIDGKSLGKRQIPWTTAPEALGYSYPYLLALQEpskGTLEVRNPDTLSLLQSISLPSASLLH 348
                 589*****************9999***********************8744366*******************99987 PP

>> Clathrin  Region in Clathrin and VPS
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0      0.18   5.3e+02      13      33 ..     382     402 ..     375     434 .. 0.85
   2 ?    0.4   0.0      0.19   5.6e+02       5      29 ..     639     663 ..     628     683 .. 0.72
   3 !   25.1   2.8   4.3e-09   1.3e-05      14     111 ..     756     872 ..     746     878 .] 0.90

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.18
                 CHHHHHCTT-HHHHCHHHCCH CS
    Clathrin  13 vvklfeeaglleelleyLekv 33 
                  ++++ e+g+l+e++++L ++
  EEA22549.1 382 QIDALIENGYLDEAISLLNML 402
                 588999999999999999887 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.19
                 CTTS-CCCCHHHHHCTT-HHHHCHH CS
    Clathrin   5 tdpidlsrvvklfeeaglleelley 29 
                  + +d + v++ +ee+g+ +el+ +
  EEA22549.1 639 ANFCDPDVVMEKLEEHGRDTELIDF 663
                 4556667777777777777777654 PP

  == domain 3  score: 25.1 bits;  conditional E-value: 4.3e-09
                 HHHHHCTT-HHHHCHHHCCHHHCHTS--HHHHHHHHHHHHHT.................T-HHHHHHTTSS---S-TTHHHHHH..HT-SSHHHHHHHH CS
    Clathrin  14 vklfeeaglleelleyLekvlkedskenpalqtallelyaky.................ddpqeleeflkknnnydlekvaklc..ekadlyeeavily 93 
                 v++f e+    +++ yLe v++e +  +p+l+ +ll ly++                   +  + +eflk++++y ++k+++l+  e+ + ye + i++
  EEA22549.1 756 VEEFLEKIDVALAIRYLEHVIDELNDLSPDLHQRLLHLYLERlksyektceedeetytlWQ-AKFLEFLKSSSQYSPAKMLNLLprEDPNFYEARAIVF 853
                 6777777788899********9999999*****************************9944.69********************988889********* PP

                 HTTXTHSSHSSX.SSSSHC CS
    Clathrin  94 kkinefkkaisl.lkklkd 111
                 +k++++ +a+++ + klk+
  EEA22549.1 854 SKMGQHRQALEIyVFKLKE 872
                 ***********96666665 PP

>> PPR  PPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   0.0    0.0011       3.2       7      27 ..     383     403 ..     383     405 .. 0.91
   2 ?   -1.9   0.1       1.7   5.2e+03       6      24 ..     660     678 ..     660     680 .. 0.84
   3 ?    0.6   0.0      0.29   8.8e+02      10      23 ..     853     866 ..     851     867 .. 0.90

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0011
         PPR   7 IsgycknGkleeAlelfkeMk 27 
                 I+++  nG+l+eA++l++ ++
  EEA22549.1 383 IDALIENGYLDEAISLLNMLE 403
                 899**************9876 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 1.7
         PPR   6 lIsgycknGkleeAlelfk 24 
                 lI+ y  + +++ Alel+ 
  EEA22549.1 660 LIDFYYGKKMHRRALELLL 678
                 688888899999****985 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.29
         PPR  10 ycknGkleeAlelf 23 
                 ++k G+++ Ale++
  EEA22549.1 853 FSKMGQHRQALEIY 866
                 89**********97 PP

>> ERO1  Endoplasmic Reticulum Oxidoreductin 1 (ERO1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.1   8.8e-05      0.26      85     119 ..      69     103 ..      36     110 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 8.8e-05
        ERO1  85 eeedyceledeeeeeavyvdLlenperfTgYkGes 119
                  +++  + +++e+++++ vdLl+  e+fT Yk e+
  EEA22549.1  69 AKDESQQQQQQEASTVNLVDLLREQEKFTRYKAEQ 103
                 344556667777788*****************987 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.3     0.008        24       6      43 ..     381     418 ..     378     425 .. 0.81
   2 ?   -2.2   0.0       3.6   1.1e+04      41      41 ..     790     790 ..     764     815 .. 0.56
   3 ?    2.5   0.0      0.12   3.5e+02       2      24 ..     844     866 ..     843     866 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.008
      TPR_14   6 alaeallalGdpdeAiallrralalaPddaeawlllaq 43 
                 +  +al ++G +deAi ll+ + ++  +d + +l+ aq
  EEA22549.1 381 DQIDALIENGYLDEAISLLNMLEDALLKDKAGRLREAQ 418
                 67789***************998877777776666554 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 3.6
      TPR_14  41 l 41 
                 l
  EEA22549.1 790 L 790
                 2 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.12
      TPR_14   2 eallalaeallalGdpdeAiall 24 
                 + + a+a ++   G++++A++++
  EEA22549.1 844 NFYEARAIVFSKMGQHRQALEIY 866
                 567799*************9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (878 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       567  (0.0316247); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.67u 0.29s 00:00:00.96 Elapsed: 00:00:00.45
# Mc/sec: 5861.89
//
Query:       EEA22550.1  [L=454]
Description: fructose-2,6-bisphosphatase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.4e-77  260.0   0.1    1.8e-77  259.6   0.1    1.1  1  6PF2K       6-phosphofructo-2-kinase
      6e-40  137.0   0.0    9.6e-40  136.4   0.0    1.3  1  His_Phos_1  Histidine phosphatase superfamily (branch 1)
    7.9e-05   22.2   0.0    0.00012   21.7   0.0    1.2  1  KTI12       Chromatin associated protein KTI12
    0.00012   22.3   0.0    0.00026   21.2   0.0    1.6  1  AAA_33      AAA domain


Domain annotation for each model (and alignments):
>> 6PF2K  6-phosphofructo-2-kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  259.6   0.1   4.1e-81   1.8e-77       5     223 .]      16     232 ..      12     232 .. 0.97

  Alignments for each domain:
  == domain 1  score: 259.6 bits;  conditional E-value: 4.1e-81
                 HHHHT..S-EEEEEESSTTSSHHHHHHHHHHHHHHTT--EEEEEHHHHHHHHHSS---GGGGSTT-HHHHHHHHHHHHHHHHHHHHHHHTS--SEEEEE CS
       6PF2K   5 tvtnlknsklvivlvGLpargKtyiskkltrylkwlgvrtkvFnvgkyrreaskalsdaeffrpdneealklreklalaalkdllaylneeegqvaifD 103
                  + + +++k+++v+vGLpargK++i+ k  ryl w+g+++++Fnvg yrr++s +   a+ff+p+n+e+ k+r+ +a aa++d+l++++e +g v+ifD
  EEA22550.1  16 FYASSDDTKICVVMVGLPARGKSLIAGKALRYLAWVGISARIFNVGTYRRKISPH-PVANFFDPHNSEGEKMRRAAAEAAVSDMLKWFKESNGVVGIFD 113
                 56677899********************************************998.5689*************************************** PP

                 S---SHHHHHHHHHHHHHTT-EEEEEEEE--HHHHHHHHHHHHTTTSGGGTTS-HHHHHHHHHHHHHHHHTT-----TTTTTTSEEEEEETTTTEEEEE CS
       6PF2K 104 AtNttrerRklilefveennlkvlflesicsdeeiikeNikevklsspDYkdketeeaikdflkRlenyekqyeplddeedeelsyIkvidvgkslvvn 202
                 AtN+t++rR++i ++++e ++++lf+es+c+de+ii +Ni evk++spDY+++++e a +df +R++nyek+ye +d ++++  +y+k+i+vg+ +++n
  EEA22550.1 114 ATNSTKQRRAWIHKTCTEAGIETLFVESSCDDEDIIMNNILEVKTTSPDYEGQDPEIAAQDFRNRIRNYEKVYETID-DDEKAYTYVKLINVGSTVIIN 211
                 *****************************************************************************.678899*************** PP

                 ---SHHHHHHHHHHTT---S- CS
       6PF2K 203 nvqgylqsrivyyllNihlkp 223
                 ++++yl sr vyy+ N+h kp
  EEA22550.1 212 QIKDYLSSRLVYYIQNLHIKP 232
                 ******************987 PP

>> His_Phos_1  Histidine phosphatase superfamily (branch 1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  136.4   0.0   2.1e-43   9.6e-40       1     189 [.     235     423 ..     235     428 .. 0.93

  Alignments for each domain:
  == domain 1  score: 136.4 bits;  conditional E-value: 2.1e-43
                 EEEEE---BTTB--....TT----B-HHHHHHHHHHHHHHTT..S---EE...EE-SSHHHHHHHHHHHHCTT--EEE-GGGS----GGGTT-B.HHHH CS
  His_Phos_1   1 lyLvRHGetewnaegrlqgrtdvpLteeGreqAealaerlag..epidai...ysSplkRarqTaeliaealglpveldegLrEidfGdweglttaeia 94 
                 ++L RHGe+e+n +g+++g  d++++ +G++ A+al   l++  +p+ +    ++S+lkR++qTa+++a+++g +  ++++L+E+d G+++glt++eia
  EEA22550.1 235 IWLSRHGESEYNLTGKIGG--DSDISTRGEAYARALPGLLKQsgVPPGTKltiWTSTLKRTIQTARHLAAETGYDKLEWKALDELDSGVCDGLTYEEIA 331
                 89************97776..66679****************66444444688********************************************** PP

                 HH..HSHHHHHHHHH-GGG-BS-BHHHHHHHHHHHHHHHHHHTTTSEEEEEE-HHHHHHHHHHHHT--GGGGGGB---TT-EEEEEE-SS-EEEE CS
  His_Phos_1  95 eeypeeleawlrdpadvrppggEsledvaaRvaaaleelaarhegetvlvVsHggvirallarllglpleelrrleldnaslsvlefdeggwrlv 189
                 e+ype+++a+++d++++r+ ggEs++dv+ R+++++ el+++++   +++V+H++v+r++++++ +++ e+ + +e++ ++l +l+ ++ g + +
  EEA22550.1 332 EKYPEDFAARDEDKYNYRYRGGESYRDVVIRLEPIIMELERSEN---IMIVTHQAVLRCIYSYFHNMSQEQSPWMEVPLHTLIKLTPRAYGTEEQ 423
                 ***************************************99986...************************************999988877655 PP

>> KTI12  Chromatin associated protein KTI12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.7   0.0   2.6e-08   0.00012       4     122 ..      27     160 ..      26     222 .. 0.80

  Alignments for each domain:
  == domain 1  score: 21.7 bits;  conditional E-value: 2.6e-08
                 EEEE--TTSSHHHHHHHHHHHHHHTT--EEEE-THHHH.........TTSSS--GGGHHHHHHHHHHHHHHHH.....TT.SEEEE-S---SHHHHHHH CS
       KTI12   4 vvltGlPssGKstrakeLakaleeekrsvvviddeslg........iekdsykdsakekalRsslrsavkrdL.....skekvVIvDslnyikgfRYeL 89 
                 vv+ GlP+ GKs +a +  ++l+  ++s  + +  +++         +  + ++s+ ek+ R++  +av+  L     s+  v I D++n +k  R  +
  EEA22550.1  27 VVMVGLPARGKSLIAGKALRYLAWVGISARIFNVGTYRrkisphpvANFFDPHNSEGEKMRRAAAEAAVSDMLkwfkeSNGVVGIFDATNSTKQRRAWI 125
                 89*******************************9999988656553333345699****************9944443344566*************** PP

                 HHHHHHTT-EEEEEEEE--HHHHHHHH..HHTT-S CS
       KTI12  90 yciakaakttlcvvyvvapldvlvkwn..eereek 122
                 +  + +a ++   v   ++ + ++  n  e ++++
  EEA22550.1 126 HKTCTEAGIETLFVESSCDDEDIIMNNilEVKTTS 160
                 ******************98888877755333333 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.0   5.9e-08   0.00026       2     113 ..      27     150 ..      26     180 .. 0.78

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 5.9e-08
      AAA_33   2 vllvGlpGsGKstlaerllkklgavllssdt.....lrrrlfg.......tdqqsktdytrvldrlyqilnelarkal.sagrnvildatnlsrrerar 87 
                 v++vGlp+ GKs  a + l+ l++v +s  +     +rr++ +       +  +s+   +  +  + + ++++++    s g   i+datn ++++ra+
  EEA22550.1  27 VVMVGLPARGKSLIAGKALRYLAWVGISARIfnvgtYRRKISPhpvanffDPHNSE-GEKMRRAAAEAAVSDMLKWFKeSNGVVGIFDATNSTKQRRAW 124
                 89*********************888888876666688888888888775222233.333334445555556664433166666899************ PP

      AAA_33  88 flklarrlgvpvrivvvetdeetlke 113
                 + k   ++g + + v  ++d+e +  
  EEA22550.1 125 IHKTCTEAGIETLFVESSCDDEDIIM 150
                 ***********999999999998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (454 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       521  (0.0290591); expected 358.6 (0.02)
Passed bias filter:                      430  (0.0239835); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.76u 0.31s 00:00:01.07 Elapsed: 00:00:00.57
# Mc/sec: 2381.92
//
Query:       EEA22551.1  [L=454]
Description: fructose-2,6-bisphosphatase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    3.2e-77  258.8   0.1    4.5e-77  258.3   0.1    1.1  1  6PF2K       6-phosphofructo-2-kinase
    6.1e-40  137.0   0.0    9.6e-40  136.4   0.0    1.3  1  His_Phos_1  Histidine phosphatase superfamily (branch 1)
    7.9e-05   22.2   0.0    0.00012   21.7   0.0    1.2  1  KTI12       Chromatin associated protein KTI12
    0.00012   22.3   0.0    0.00026   21.2   0.0    1.6  1  AAA_33      AAA domain
  ------ inclusion threshold ------
       0.14   11.4   0.0        7.1    5.9   0.0    2.3  2  Zeta_toxin  Zeta toxin


Domain annotation for each model (and alignments):
>> 6PF2K  6-phosphofructo-2-kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  258.3   0.1   1.3e-80   4.5e-77      10     223 .]      21     232 ..      13     232 .. 0.97

  Alignments for each domain:
  == domain 1  score: 258.3 bits;  conditional E-value: 1.3e-80
                 ..S-EEEEEESSTTSSHHHHHHHHHHHHHHTT--EEEEEHHHHHHHHHSS---GGGGSTT-HHHHHHHHHHHHHHHHHHHHHHHTS--SEEEEES---S CS
       6PF2K  10 knsklvivlvGLpargKtyiskkltrylkwlgvrtkvFnvgkyrreaskalsdaeffrpdneealklreklalaalkdllaylneeegqvaifDAtNtt 108
                 +++k+++v+vGLpargK++i+ k  ryl w+g+++++Fnvg yrr++s +   a+ff+p+n+e+ k+r+ +a aa++d+l++++e +g v+ifDAtN+t
  EEA22551.1  21 DDTKICVVMVGLPARGKSLIAGKALRYLAWVGISARIFNVGTYRRKISPH-PVANFFDPHNSEGEKMRRAAAEAAVSDMLKWFKESNGVVGIFDATNST 118
                 689********************************************998.5689******************************************** PP

                 HHHHHHHHHHHHHTT-EEEEEEEE--HHHHHHHHHHHHTTTSGGGTTS-HHHHHHHHHHHHHHHHTT-----TTTTTTSEEEEEETTTTEEEEE---SH CS
       6PF2K 109 rerRklilefveennlkvlflesicsdeeiikeNikevklsspDYkdketeeaikdflkRlenyekqyeplddeedeelsyIkvidvgkslvvnnvqgy 207
                 ++rR++i ++++e ++++lf+es+c+de+ii +Ni evk++spDY+++++e a +df +R++nyek+ye +d ++++  +y+k+i+vg+ +++n++++y
  EEA22551.1 119 KQRRAWIHKTCTEAGIETLFVESSCDDEDIIMNNILEVKTTSPDYEGQDPEIAAQDFRNRIRNYEKVYETID-DDEKAYTYVKLINVGSTVIINQIKDY 216
                 ************************************************************************.678899******************** PP

                 HHHHHHHHHTT---S- CS
       6PF2K 208 lqsrivyyllNihlkp 223
                 l sr vyy+ N+h kp
  EEA22551.1 217 LSSRLVYYIQNLHIKP 232
                 *************987 PP

>> His_Phos_1  Histidine phosphatase superfamily (branch 1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  136.4   0.0   2.7e-43   9.6e-40       1     189 [.     235     423 ..     235     428 .. 0.93

  Alignments for each domain:
  == domain 1  score: 136.4 bits;  conditional E-value: 2.7e-43
                 EEEEE---BTTB--....TT----B-HHHHHHHHHHHHHHTT..S---EE...EE-SSHHHHHHHHHHHHCTT--EEE-GGGS----GGGTT-B.HHHH CS
  His_Phos_1   1 lyLvRHGetewnaegrlqgrtdvpLteeGreqAealaerlag..epidai...ysSplkRarqTaeliaealglpveldegLrEidfGdweglttaeia 94 
                 ++L RHGe+e+n +g+++g  d++++ +G++ A+al   l++  +p+ +    ++S+lkR++qTa+++a+++g +  ++++L+E+d G+++glt++eia
  EEA22551.1 235 IWLSRHGESEYNLTGKIGG--DSDISTRGEAYARALPGLLKQsgVPPGTKltiWTSTLKRTIQTARHLAAETGYDKLEWKALDELDSGVCDGLTYEEIA 331
                 89************97776..66679****************66444444688********************************************** PP

                 HH..HSHHHHHHHHH-GGG-BS-BHHHHHHHHHHHHHHHHHHTTTSEEEEEE-HHHHHHHHHHHHT--GGGGGGB---TT-EEEEEE-SS-EEEE CS
  His_Phos_1  95 eeypeeleawlrdpadvrppggEsledvaaRvaaaleelaarhegetvlvVsHggvirallarllglpleelrrleldnaslsvlefdeggwrlv 189
                 e+ype+++a+++d++++r+ ggEs++dv+ R+++++ el+++++   +++V+H++v+r++++++ +++ e+ + +e++ ++l +l+ ++ g + +
  EEA22551.1 332 EKYPEDFAARDEDKYNYRYRGGESYRDVVIRLEPIIMELERSEN---IMIVTHQAVLRCIYSYFHNMSQEQSPWMEVPLHTLIKLTPRAYGTEEQ 423
                 ***************************************99986...************************************999988877655 PP

>> KTI12  Chromatin associated protein KTI12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.7   0.0   3.3e-08   0.00012       4     122 ..      27     160 ..      26     222 .. 0.80

  Alignments for each domain:
  == domain 1  score: 21.7 bits;  conditional E-value: 3.3e-08
                 EEEE--TTSSHHHHHHHHHHHHHHTT--EEEE-THHHH.........TTSSS--GGGHHHHHHHHHHHHHHHH.....TT.SEEEE-S---SHHHHHHH CS
       KTI12   4 vvltGlPssGKstrakeLakaleeekrsvvviddeslg........iekdsykdsakekalRsslrsavkrdL.....skekvVIvDslnyikgfRYeL 89 
                 vv+ GlP+ GKs +a +  ++l+  ++s  + +  +++         +  + ++s+ ek+ R++  +av+  L     s+  v I D++n +k  R  +
  EEA22551.1  27 VVMVGLPARGKSLIAGKALRYLAWVGISARIFNVGTYRrkisphpvANFFDPHNSEGEKMRRAAAEAAVSDMLkwfkeSNGVVGIFDATNSTKQRRAWI 125
                 89*******************************9999988656553333345699****************9944443344566*************** PP

                 HHHHHHTT-EEEEEEEE--HHHHHHHH..HHTT-S CS
       KTI12  90 yciakaakttlcvvyvvapldvlvkwn..eereek 122
                 +  + +a ++   v   ++ + ++  n  e ++++
  EEA22551.1 126 HKTCTEAGIETLFVESSCDDEDIIMNNilEVKTTS 160
                 ******************98888877755333333 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.0   7.3e-08   0.00026       2     113 ..      27     150 ..      26     180 .. 0.78

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 7.3e-08
      AAA_33   2 vllvGlpGsGKstlaerllkklgavllssdt.....lrrrlfg.......tdqqsktdytrvldrlyqilnelarkal.sagrnvildatnlsrrerar 87 
                 v++vGlp+ GKs  a + l+ l++v +s  +     +rr++ +       +  +s+   +  +  + + ++++++    s g   i+datn ++++ra+
  EEA22551.1  27 VVMVGLPARGKSLIAGKALRYLAWVGISARIfnvgtYRRKISPhpvanffDPHNSE-GEKMRRAAAEAAVSDMLKWFKeSNGVVGIFDATNSTKQRRAW 124
                 89*********************888888876666688888888888775222233.333334445555556664433166666899************ PP

      AAA_33  88 flklarrlgvpvrivvvetdeetlke 113
                 + k   ++g + + v  ++d+e +  
  EEA22551.1 125 IHKTCTEAGIETLFVESSCDDEDIIM 150
                 ***********999999999998765 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.0     0.002       7.1      10      40 ..      18      48 ..      10      73 .. 0.84
   2 ?    3.1   0.0     0.014        49      49      76 ..     170     199 ..     156     220 .. 0.77

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.002
  Zeta_toxin 10 ypsqerPklillgGqpGAGKselaellkdel 40
                +ps+++++ ++++G p+ GKs +a ++ ++l
  EEA22551.1 18 IPSDDTKICVVMVGLPARGKSLIAGKALRYL 48
                67889******************99988876 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.014
  Zeta_toxin  49 ldpDdlRelhPeyeeilk..adpkkaselt 76 
                 + + d+R+++++ye++++  +d++ka+ ++
  EEA22551.1 170 IAAQDFRNRIRNYEKVYEtiDDDEKAYTYV 199
                 77889************9443555555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (454 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       524  (0.0292264); expected 358.6 (0.02)
Passed bias filter:                      435  (0.0242624); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.72u 0.35s 00:00:01.06 Elapsed: 00:00:00.58
# Mc/sec: 2367.06
//
Query:       EEA22552.1  [L=446]
Description: fructose-2,6-bisphosphatase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.5e-64  217.4   0.2    2.1e-64  216.9   0.2    1.1  1  6PF2K       6-phosphofructo-2-kinase
    5.9e-40  137.0   0.0    9.2e-40  136.4   0.0    1.3  1  His_Phos_1  Histidine phosphatase superfamily (branch 1)


Domain annotation for each model (and alignments):
>> 6PF2K  6-phosphofructo-2-kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  216.9   0.2   2.3e-68   2.1e-64      34     223 .]      37     224 ..      33     224 .. 0.98

  Alignments for each domain:
  == domain 1  score: 216.9 bits;  conditional E-value: 2.3e-68
                 HHHHHHTT--EEEEEHHHHHHHHHSS---GGGGSTT-HHHHHHHHHHHHHHHHHHHHHHHTS--SEEEEES---SHHHHHHHHHHHHHTT-EEEEEEEE CS
       6PF2K  34 trylkwlgvrtkvFnvgkyrreaskalsdaeffrpdneealklreklalaalkdllaylneeegqvaifDAtNttrerRklilefveennlkvlflesi 132
                  ryl w+g+++++Fnvg yrr++s +   a+ff+p+n+e+ k+r+ +a aa++d+l++++e +g v+ifDAtN+t++rR++i ++++e ++++lf+es+
  EEA22552.1  37 LRYLAWVGISARIFNVGTYRRKISPH-PVANFFDPHNSEGEKMRRAAAEAAVSDMLKWFKESNGVVGIFDATNSTKQRRAWIHKTCTEAGIETLFVESS 134
                 59*********************998.5689******************************************************************** PP

                 --HHHHHHHHHHHHTTTSGGGTTS-HHHHHHHHHHHHHHHHTT-----TTTTTTSEEEEEETTTTEEEEE---SHHHHHHHHHHTT---S- CS
       6PF2K 133 csdeeiikeNikevklsspDYkdketeeaikdflkRlenyekqyeplddeedeelsyIkvidvgkslvvnnvqgylqsrivyyllNihlkp 223
                 c+de+ii +Ni evk++spDY+++++e a +df +R++nyek+ye +d ++++  +y+k+i+vg+ +++n++++yl sr vyy+ N+h kp
  EEA22552.1 135 CDDEDIIMNNILEVKTTSPDYEGQDPEIAAQDFRNRIRNYEKVYETID-DDEKAYTYVKLINVGSTVIINQIKDYLSSRLVYYIQNLHIKP 224
                 ************************************************.678899*********************************987 PP

>> His_Phos_1  Histidine phosphatase superfamily (branch 1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  136.4   0.0     1e-43   9.2e-40       1     189 [.     227     415 ..     227     420 .. 0.93

  Alignments for each domain:
  == domain 1  score: 136.4 bits;  conditional E-value: 1e-43
                 EEEEE---BTTB--....TT----B-HHHHHHHHHHHHHHTT..S---EE...EE-SSHHHHHHHHHHHHCTT--EEE-GGGS----GGGTT-B.HHHH CS
  His_Phos_1   1 lyLvRHGetewnaegrlqgrtdvpLteeGreqAealaerlag..epidai...ysSplkRarqTaeliaealglpveldegLrEidfGdweglttaeia 94 
                 ++L RHGe+e+n +g+++g  d++++ +G++ A+al   l++  +p+ +    ++S+lkR++qTa+++a+++g +  ++++L+E+d G+++glt++eia
  EEA22552.1 227 IWLSRHGESEYNLTGKIGG--DSDISTRGEAYARALPGLLKQsgVPPGTKltiWTSTLKRTIQTARHLAAETGYDKLEWKALDELDSGVCDGLTYEEIA 323
                 89************97776..66679****************66444444688********************************************** PP

                 HH..HSHHHHHHHHH-GGG-BS-BHHHHHHHHHHHHHHHHHHTTTSEEEEEE-HHHHHHHHHHHHT--GGGGGGB---TT-EEEEEE-SS-EEEE CS
  His_Phos_1  95 eeypeeleawlrdpadvrppggEsledvaaRvaaaleelaarhegetvlvVsHggvirallarllglpleelrrleldnaslsvlefdeggwrlv 189
                 e+ype+++a+++d++++r+ ggEs++dv+ R+++++ el+++++   +++V+H++v+r++++++ +++ e+ + +e++ ++l +l+ ++ g + +
  EEA22552.1 324 EKYPEDFAARDEDKYNYRYRGGESYRDVVIRLEPIIMELERSEN---IMIVTHQAVLRCIYSYFHNMSQEQSPWMEVPLHTLIKLTPRAYGTEEQ 415
                 ***************************************99986...************************************999988877655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (446 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       487  (0.0271627); expected 358.6 (0.02)
Passed bias filter:                      403  (0.0224776); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.69u 0.35s 00:00:01.04 Elapsed: 00:00:00.55
# Mc/sec: 2441.42
//
Query:       EEA22553.1  [L=326]
Description: ribonucleoprotein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.5e-22   76.8   0.1    1.1e-15   57.2   0.0    3.0  2  RRM_1         RNA recognition motif. (a.k.a. RRM, RBD, or RNP
     0.0036   17.1   0.0       0.23   11.4   0.0    2.6  2  RRM_occluded  Occluded RNA-recognition motif
  ------ inclusion threshold ------
      0.098   12.9   0.0       0.91    9.7   0.0    2.1  2  Laminin_G_1   Laminin G domain
       0.11   12.1   0.0       0.23   11.1   0.0    1.5  1  RRM_5         RNA recognition motif. (a.k.a. RRM, RBD, or RNP


Domain annotation for each model (and alignments):
>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.2   0.0   2.4e-19   1.1e-15       1      70 []      82     153 ..      82     153 .. 0.97
   2 !   15.8   0.1   2.1e-06    0.0092       1      62 [.     214     284 ..     214     287 .. 0.77

  Alignments for each domain:
  == domain 1  score: 57.2 bits;  conditional E-value: 2.4e-19
                 EEEESETTTSSHHHHHHHHHT.TSCEEEEEEEEE.TTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEEE CS
       RRM_1   1 lfVgnLppdvteeeLkelFsk.fGpiksiklvrd.etgkskgfafVeFeskedAekAlealngkklggrelk 70 
                 l+Vgn p+++++e+++++F++   +i++i+++ d  tg++  ++fVe ++ke+A++A+ +l+gk l+gr+++
  EEA22553.1  82 LYVGNMPYTAKREDVETIFEGgEYSIERIDISIDpFTGRNPSYCFVELATKEQADRAMVELDGKDLQGRPIR 153
                 8********************77799*******************************************996 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 2.1e-06
                 EEEESETTTSSHH....HHHHHHHTTSCEEEEEEEEE.TTTSEEE....EEEEEESSHHHHHHHHHHHTTE CS
       RRM_1   1 lfVgnLppdvtee....eLkelFskfGpiksiklvrd.etgkskg....fafVeFeskedAekAlealngk 62 
                 l+Vg+Lp+ ++++    ++ ++F++++     kl++    ++  +    + fV+F++ e+A++A  al+g+
  EEA22553.1 214 LYVGGLPKIMDKQaldaDIQAFFKGYNLEAISKLITPhPSKRFEPgdhyYLFVDFATIEEAAAAQTALDGQ 284
                 89****999998822225578*****9998888888663333322344489******************97 PP

>> RRM_occluded  Occluded RNA-recognition motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.4   0.0   5.1e-05      0.23      41      70 ..     125     154 ..      82     156 .. 0.94
   2 ?    3.2   0.0     0.018        82      42      72 ..     265     296 ..     228     299 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 5.1e-05
  RRM_occluded  41 AivefkdekiagkasLaLdgsefegkklrc 70 
                   ++ve++ +++a +a+ +Ldg++++g+ +r+
    EEA22553.1 125 CFVELATKEQADRAMVELDGKDLQGRPIRI 154
                   78*************************996 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.018
  RRM_occluded  42 ivefkdekiagkasLaLdgsefe.gkklrcGt 72 
                   +v f+  + a+ a+ aLdg++   g klr G 
    EEA22553.1 265 FVDFATIEEAAAAQTALDGQDGPwGGKLRLGR 296
                   68999999***********9986688888886 PP

>> Laminin_G_1  Laminin G domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.14   6.4e+02      91     118 ..      78     102 ..      56     111 .. 0.76
   2 ?    9.7   0.0    0.0002      0.91      81     118 ..     202     238 ..     137     240 .. 0.65

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.14
                  ECSEEEESSSSGSTCCCSCCCCCSB-EE CS
  Laminin_G_1  91 vnkklyvGGlpdekvkkealaistsfkG 118
                    + lyvG +p   ++++++++ t f+G
   EEA22553.1  78 EGRRLYVGNMP---YTAKREDVETIFEG 102
                  4456*******...66666666666666 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.0002
                  S-TT-SS..SEEECSEEEESSSS.GSTCCCSCCCCCSB-EE CS
  Laminin_G_1  81 splgatt..tlnvnkklyvGGlp.dekvkkealaistsfkG 118
                  + +      +++ ++ lyvGGlp  + +++ +++i+  fkG
   EEA22553.1 202 N-S---KpnDIENSRRLYVGGLPkIMDKQALDADIQAFFKG 238
                  2.2...2335788888*******655566666666666777 PP

>> RRM_5  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   5.2e-05      0.23      64     106 ..     122     168 ..     111     186 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 5.2e-05
       RRM_5  64 ketalvqmgdasaveravqHLnnaklfgkrleval....SKqqavse 106
                 + + +v+++   +++ra+  L ++ l g+++++++    S q+ vs+
  EEA22553.1 122 PSYCFVELATKEQADRAMVELDGKDLQGRPIRIKPgvakSAQDRVSS 168
                 67899************************888764222255555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (326 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       427  (0.0238162); expected 358.6 (0.02)
Passed bias filter:                      301  (0.0167884); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.59u 0.37s 00:00:00.96 Elapsed: 00:00:00.55
# Mc/sec: 1795.78
//
Query:       EEA22554.1  [L=265]
Description: phosphoglycerate mutase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      2e-27   96.1   0.0      3e-27   95.6   0.0    1.2  1  His_Phos_1  Histidine phosphatase superfamily (branch 1)


Domain annotation for each model (and alignments):
>> His_Phos_1  Histidine phosphatase superfamily (branch 1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.6   0.0   1.7e-31     3e-27       1     160 [.       3     169 ..       3     179 .. 0.87

  Alignments for each domain:
  == domain 1  score: 95.6 bits;  conditional E-value: 1.7e-31
                 EEEEE---BTTB--....TT----B-HHHHHHHHHHHHHHTT..S---EEEE-SSHHHHHHHHHHHHCTT..--EEE-GGGS----GGGTT-B.HHHHH CS
  His_Phos_1   1 lyLvRHGetewnaegrlqgrtdvpLteeGreqAealaerlag..epidaiysSplkRarqTaeliaealg..lpveldegLrEidfGdweglttaeiae 95 
                 +y++RH+et +n+ +++ g t++ Lt +G+ q+++la+++++  ++++++++S+l+Ra+ Tae i++      +v +++ LrE +fG  eg     i++
  EEA22554.1   3 IYFIRHAETVHNVGQTWAGTTNSALTNHGVLQIQRLAAFFRSaaVKFEHVFTSDLSRAVITAEGICNPNIsdAQVMVTPLLREQHFGSREGI---RIHA 98 
                 8**************************************999889*********************977688********************...5555 PP

                 H..HSHHHHHHHHH-GGG-BS-BHHHHHHHHHHHHH........HHHHHTTTSE..EEEEE-HHHHHHHHHHHH.T CS
  His_Phos_1  96 eypeeleawlrdpadvrppggEsledvaaRvaaale........elaarheget..vlvVsHggvirallarll.g 160
                 +      + +r+p++v+p++ E+ e ++ R+ ++le           +++ +++  +++V+Hg ++r+l + ++  
  EEA22554.1  99 A-----TTASRSPPTVEPEPAETEESMRTRANRFLEeylfpvllSYDDDQTEKDsaIAIVAHGIILRVLWNCFMhA 169
                 5.....55577888899999****************99998776333333333367*************9998844 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (265 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       452  (0.0252106); expected 358.6 (0.02)
Passed bias filter:                      416  (0.0232026); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.33s 00:00:00.93 Elapsed: 00:00:00.54
# Mc/sec: 1467.62
//
Query:       EEA22555.1  [L=640]
Description: MFS sugar transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-91  306.9  28.2    2.8e-91  306.6  28.2    1.0  1  Sugar_tr  Sugar (and other) transporter
    7.6e-15   54.7  45.8    5.1e-13   48.7  17.1    2.1  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  306.6  28.2   3.2e-95   2.8e-91       5     452 .]     134     584 ..     130     584 .. 0.94

  Alignments for each domain:
  == domain 1  score: 306.6 bits;  conditional E-value: 3.2e-95
                 HHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHH.HHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS- CS
    Sugar_tr   5 aalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaii.GslfagllgdrfGRkkslliaavlfvigavlqaaakgknsv 102
                  +++  ++g d  v+++++ l+k  ++fg + ++     s+ l+gl+ ++ ++ ++i G+ ++ ++ ++fGR+ ++ i++v+++ + + q++ +   ++
  EEA22555.1 134 CSICAAVQGMDETVVNGAQVLYK--SQFGIDGNDP--R-STWLLGLLNAAPYLCCAIaGCWLTIPFNHWFGRRGTIFITCVISSLACIWQGFVN---TW 224
                 67888999***************..8888888884..3.57899999888887775538899999*****************************...9* PP

                 TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-.....TTHHHHHHHCCHHHHHHHHHHGGGS---HH CS
    Sugar_tr 103 evlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsn.....adgwrillglqlvpallllilllflPESPr 196
                 + ++v+R+++G+g+G  s++vP+y++E +p+++Rgalv+ +q++++fGi++++  +l++ ++ +        wr+++g++++pa+l+++l++++PESPr
  EEA22555.1 225 WHMFVARFVLGFGIGPKSATVPIYAAETSPPAIRGALVMQWQMWTAFGIMFGYAADLAFFQVPDpphicGFNWRLMMGSACIPAILVCLLVFVCPESPR 323
                 ***********************************************************988888***9999*************************** PP

                 HHHHTT-HHHHHHHHHHHHHC.HHHHHHHHHHHHHHHHHHH.......HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH..H CS
    Sugar_tr 197 ylvekgkeeeakevlaklrge.edadrelaeekdsleaeqeee..kaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsks..l 290
                 ++++kg++++a +++ +lr +  +a r++  +++ leae +++  ++++ e+++   +r++ll    ++++qq++G+n+i yys++if ++ +s+   +
  EEA22555.1 324 WYMSKGRYDKAYQTMCRLRYSkLQAARDVFYIYTLLEAETSMRlgQNKVLEMITVPRNRRALLASEIVMFLQQFCGVNVIAYYSSQIFLEANFSPIsaF 422
                 *****************999868899*************998888888888888888**************************************999* PP

                 HHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS....CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHH CS
    Sugar_tr 291 lvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgivalllvaks.kaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskal 388
                  ++++ gvvn+++ + a++++d fGRR+lll  + +mai +++ g   + +++++ +a  +++  +i+lf +++++g gpvp+ +++E +p+ vRs ++
  EEA22555.1 423 GASLGWGVVNWLFAIPAVYTIDTFGRRNLLLCTFPMMAISMFFTG-FSFYIPETHhTARIGCIALGIFLFGVVYSPGEGPVPFTYSAEAYPLYVRSYGM 520
                 ********************************************9.77777777735555566679********************************* PP

                 HHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 389 aiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 ++a+a+ w++nf+ +++ p + ++ + ++ f+ +++ +v++   +++f+petkg+tlee++++f
  EEA22555.1 521 SLATATTWFFNFILAMTWPSLSSSFTTAGGFAWYGAWNVVGWWLILMFMPETKGKTLEELDQVF 584
                 *************************************************************997 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.7  17.1   5.6e-17   5.1e-13       2     231 ..     135     408 ..     134     431 .. 0.77
   2 !    6.9  27.5   0.00028       2.5      28     172 ..     415     569 ..     385     600 .. 0.69

  Alignments for each domain:
  == domain 1  score: 48.7 bits;  conditional E-value: 5.6e-17
       MFS_1   2 llaaflsalarsilgpalplalaedlgispse......igllltl....yalgaavaslplGrlsdrfGrrrvlllglllfalglllll.fasslwlll 89 
                 +++a++ +++ ++++ a   ++++++gi++        +gll ++    +a++ +++++p+ ++   fGrr +++++ ++++l++++   f++++w ++
  EEA22555.1 135 SICAAVQGMDETVVNGAQV-LYKSQFGIDGNDprstwlLGLLNAApylcCAIAGCWLTIPFNHW---FGRRGTIFITCVISSLACIW-QgFVNTWWHMF 228
                 68999*************9.9******9999999888888888884444555557777777777...*****666666666666233.34778888*** PP

       MFS_1  90 vlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg........Wravfyilaivsllafvlfllllpeepperk 180
                 v+r++ G+g g   +++ +++a+ +p+  rg  +  +++ +++G+++g+++  ++ +           Wr+++  ++i ++l+++   l++++++++r+
  EEA22555.1 229 VARFVLGFGIGPKSATVPIYAAETSPPAIRGALVMQWQMWTAFGIMFGYAADLAFFQVPDpphicgfnWRLMMGSACIPAILVCL---LVFVCPESPRW 324
                 *****************************************************999777799999999***************99...9999******* PP

       MFS_1 181 rkspkeee................................kgtgpaplvpawkallkdpvlw.illialllfffgfsglltllp 231
                   s+ +                                   + g+ ++++ ++  ++++ l+ + ++++l  f+g++ + +++ 
  EEA22555.1 325 YMSKGRYDkayqtmcrlrysklqaardvfyiytlleaetsMRLGQNKVLEMITVPRNRRALLaSEIVMFLQQFCGVNVIAYYSS 408
                 999888878888888888888877777777777777766644444444445566666665544344444444444444444444 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.00028
       MFS_1  28 gispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.........sslwlllvlrvlqGlga.galfpagaaliadwfpk 116
                 ++sp ++  +  + +++ +++++p+ + +d fGrr +ll+++ ++a+++++  f+         + +  ++++ +l G+ +  +  p+  ++ a+ +p 
  EEA22555.1 415 NFSPISAFGASLGWGVVNWLFAIPAVYTIDTFGRRNLLLCTFPMMAISMFFTGFSfyipethhtARIGCIALGIFLFGVVYsPGEGPVPFTYSAEAYPL 513
                 333333222444567788******************************555556333456544444556999999******78899************* PP

       MFS_1 117 eergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllll 172
                   r+ +++l++a++ +   + ++  + l+ss+   + f   ++  +++ +l+l+++
  EEA22555.1 514 YVRSYGMSLATATTWFFNFILAMTWPSLSSSFTTAGGFAWYGAWNVVGWWLILMFM 569
                 ************55555555555555555555555555555555555544433444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (640 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       651  (0.0363099); expected 358.6 (0.02)
Passed bias filter:                      400  (0.0223102); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.78u 0.35s 00:00:01.12 Elapsed: 00:00:00.56
# Mc/sec: 3433.21
//
Query:       EEA22556.1  [L=99]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
       0.13   12.1   1.1       0.18   11.6   1.1    1.1  1  Synaptobrevin  Synaptobrevin


Domain annotation for each model (and alignments):
>> Synaptobrevin  Synaptobrevin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   1.1   9.9e-06      0.18      56      86 ..      49      79 ..      47      80 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 9.9e-06
                   HHHHHHHHHTXXXXXXXXXXXXXXXXXXXXX CS
  Synaptobrevin 56 klkrkmwwknmkliiililvvlililiiiiv 86
                   +l+r++ w+   ++ii  l vl +++i++++
     EEA22556.1 49 QLRRRVTWRSSAYKIIAYLYVLGILYIVWLI 79
                   79************************99975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (99 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       473  (0.0263818); expected 358.6 (0.02)
Passed bias filter:                      306  (0.0170673); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.34s 00:00:00.87 Elapsed: 00:00:00.53
# Mc/sec: 560.96
//
Query:       EEA22557.1  [L=453]
Description: pyruvate dehydrogenase kinase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.1e-74  249.7   0.0    1.5e-74  249.2   0.0    1.2  1  BCDHK_Adom3  Mitochondrial branched-chain alpha-ketoacid dehy
    3.5e-13   50.0   0.0    6.9e-13   49.1   0.0    1.5  1  HATPase_c    Histidine kinase-, DNA gyrase B-, and HSP90-like
     0.0057   16.5   0.0      0.014   15.2   0.0    1.7  2  HATPase_c_3  Histidine kinase-, DNA gyrase B-, and HSP90-like


Domain annotation for each model (and alignments):
>> BCDHK_Adom3  Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  249.2   0.0   2.5e-78   1.5e-74       1     162 []      22     270 ..      22     270 .. 0.99

  Alignments for each domain:
  == domain 1  score: 249.2 bits;  conditional E-value: 2.5e-78
  BCDHK_Adom3   1 pvslrqlvqfgekpstgtllksaqflreelpirlAhrvkelenlPdglvenpsvkkvkdwYaqsfeellelpkpelee.................... 78 
                  +vslrq+vqfge+ps+gtl++++qfl+eelpirlAhrv+el++lPdgl+e+ps+kkvkdwYaqsfee++++pkp+l++                    
   EEA22557.1  22 GVSLRQMVQFGETPSPGTLFRASQFLSEELPIRLAHRVEELNHLPDGLNEMPSIKKVKDWYAQSFEEIINVPKPSLSDeikahlirpmrnhgkdskpl 119
                  69************************************************************************99999******************* PP

  BCDHK_Adom3  79 .....................................................................nekftelLekikkrHddvvttlaqGvlel 107
                                                                                       n++f ++L++ik+rHd+vvtt+aqG+le+
   EEA22557.1 120 settwnpsiregqyrsspdsaiisngkenhdthhhkgvngngkakltlsrryfvpaedyagwppeidayNQRFGKTLQQIKRRHDGVVTTVAQGILEY 217
                  ************************************************************************************************** PP

  BCDHK_Adom3 108 kekrkrkqidseiqsFLdrfymsRIgiRmLieqhiaLteqskskkepsdyvGiId 162
                  k+kr+r qids+iq+FLdrfymsRIgiRmLi+qhiaLteq++   ++++yvGiI+
   EEA22557.1 218 KRKRQRLQIDSRIQAFLDRFYMSRIGIRMLIGQHIALTEQTHA--HHPNYVGIIC 270
                  ****************************************875..777******9 PP

>> HATPase_c  Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.1   0.0   1.2e-16   6.9e-13       3     109 ..     316     443 ..     314     445 .. 0.81

  Alignments for each domain:
  == domain 1  score: 49.1 bits;  conditional E-value: 1.2e-16
                 HHHHHHHHHHHHHHHHHH......HSTTT..EEEEEEEEEETEEEEEEEESSSSSTTHHHTGTCS.TTCH............HCSTCHTSTSSSHHHHH CS
   HATPase_c   3 ekrLrqiisnlvdNavkf......atkag..eieveikaseddlvisveDnGiGipkedlkklfe.kfsq............ddstkrggggtGlGlsi 80 
                 + +L +++ + ++N++++      a  ++   i+v +   ++d++i+++D G Gip++ ++++ +  +++            +++ k    g+G+Gl i
  EEA22557.1 316 PGHLSHMLFETLKNSLRAvvethgAEREDfpVIKVIVAEGKEDITIKISDEGGGIPRSSIPLVWTyMYTTvdqtpsldpdfdKSDFKAPMAGFGYGLPI 414
                 5789*************9765443222223244666554448*******************88887777788888887777657777779********* PP

                 HHHHHHHTTTEEEEEEETTTEEEEEEEEE CS
   HATPase_c  81 vkklvelmgGeiwvesepgrGttftftlp 109
                 ++ +++ +gG+++++s +g Gt+++++l 
  EEA22557.1 415 SRLYARYFGGDLKLISMEGYGTDVYLHLN 443
                 **************************985 PP

>> HATPase_c_3  Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       1.2     7e+03      61      85 ..     146     168 ..     141     172 .. 0.69
   2 !   15.2   0.0   2.3e-06     0.014       7      52 ..     323     377 ..     318     445 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 1.2
  HATPase_c_3  61 keakrkstslGkkGiGlklAslslg 85 
                  ke++ ++  +G  G G   A l l+
   EEA22557.1 146 KENHDTHHHKGVNGNG--KAKLTLS 168
                  5556678889999999..5665555 PP

  == domain 2  score: 15.2 bits;  conditional E-value: 2.3e-06
  HATPase_c_3   7 laelvdNsldAdaen..........vkievnknrgktgeivieDdGkGmseeelkn 52 
                  l+e ++Nsl A  e+          +k+ v + + ++ +i+i D+G G++++ +  
   EEA22557.1 323 LFETLKNSLRAVVEThgaeredfpvIKVIVAEGK-EDITIKISDEGGGIPRSSIPL 377
                  89*****************************987.799***********9998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (453 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       387  (0.0215851); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.70u 0.32s 00:00:01.02 Elapsed: 00:00:00.55
# Mc/sec: 2460.17
//
Query:       EEA22558.1  [L=673]
Description: beta-1,6 glucan synthetase (Kre6), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.7e-225  749.2   0.9   2.1e-225  748.9   0.9    1.1  1  SKN1      Beta-glucan synthesis-associated protein (SKN1)


Domain annotation for each model (and alignments):
>> SKN1  Beta-glucan synthesis-associated protein (SKN1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  748.9   0.9  1.1e-229  2.1e-225       3     501 .]     177     673 .]     175     673 .] 0.96

  Alignments for each domain:
  == domain 1  score: 748.9 bits;  conditional E-value: 1.1e-229
        SKN1   3 llseekekDDylhnpdpeakadkkkkvkdlklldkrgllnvlgllllvlgllllfivlPvltylgkkekestks.eaaeiltkaqvpllsairtslidp 100
                 l+ e+ ekDDylhnpdp   a   ++++d++++++rgl+nv+gl+llv+g+++lfi++Pv t+++   ++s++  +   ++ +++ pll+++rt+lidp
  EEA22558.1 177 LFPEDVEKDDYLHNPDP---A---DRERDCDICNNRGLANVGGLALLVTGIVALFIIYPVTTFVDGVVQSSRDPcTLDPMCISMTRPLLKNVRTGLIDP 269
                 567899*********99...3...334699**********************************6555555443388889999**************** PP

        SKN1 101 dtPesaltrkskdgkklkLvfsDefnkegrtfydGdDqfwtavdlhYaatkdlewYdpdavttadGtLelrldafknhdLnyrsGmlqsWnklCftgga 199
                  tP+sa+t+k++dg++++LvfsDefn++grtfy+GdD+f+++vdl+Y  t+dlewYdpda+tt++G+Le+++d+++nh+L +rsGmlqsWn++Cf+gg+
  EEA22558.1 270 MTPSSAMTKKAADGTEWQLVFSDEFNTPGRTFYEGDDPFFQGVDLWYGVTEDLEWYDPDAITTSNGVLEIHFDSYDNHNLSFRSGMLQSWNQMCFSGGR 368
                 *************************************************************************************************** PP

        SKN1 200 levsvsLpgkgevsGlWPglWtmGnLgRpGylasteGvWPYsY.dsCDvGitpnqssadGlsylpGqrlsaCtCkgedhpspgvgRgaPeiDileaeve 297
                 le+s+sLpg+g++sG+WPg+W+mGnLgR+Gy+a+t+G+WPYsY d CDvGit+nqss+dGls+lpG+rl+aCtC g dhpspg++RgaPeiD++ea+v+
  EEA22558.1 369 LEASISLPGRGDTSGFWPGFWAMGNLGRAGYAATTDGMWPYSYdDICDVGITANQSSTDGLSFLPGMRLPACTCPGVDHPSPGKSRGAPEIDVIEASVT 467
                 *******************************************778****************************************************9 PP

        SKN1 298 teke....vgvasqslqvaPfdiwylpdydfveiydksvtalnsyaGgpfqqalsglttlnkewyeeegkkfqkygleykpnddekgyitWfvgdektw 392
                 +  e    +gv+sqslq+aP+d+wylpdydf+++y+ s+t++n+y+Ggpfqq  sglt+ln++wy  +gk++q y++ey p+  ++g +tWfvg ektw
  EEA22558.1 468 VLDEmqdrIGVVSQSLQLAPYDTWYLPDYDFTAVYNPSITEINTYRGGPFQQVASGLTNLNNNWY--DGKEYQIYAFEYAPG--ANGNVTWFVGSEKTW 562
                 87777788*********************************************************..99***********98..89************* PP

        SKN1 393 tlkakalgpngnigqRliseepmsiilnlgisnnfaaidwkele..fpatlriDyvRlyqeedeesvgCDPedyptadYiekhkeaYenanltsweeag 489
                 t++aka++pngnigqR i+ epm+ iln+g+s +fa+++w+ l   +pat+r+Dy+R+yq+++e+s++CDP +y t++Yi++h+eaY+n+nlt w+++g
  EEA22558.1 563 TIDAKAVRPNGNIGQRVIPVEPMYPILNFGMSPSFAMLNWTGLAetWPATMRVDYIRIYQDPNEISITCDPVGYGTTEYIKQHPEAYHNPNLTLWSQTG 661
                 *******************************************777***************************************************** PP

        SKN1 490 yefpknklldec 501
                 y++pkn+++d+c
  EEA22558.1 662 YDWPKNSFVDGC 673
                 **********99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (673 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       426  (0.0237604); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.74u 0.36s 00:00:01.10 Elapsed: 00:00:00.55
# Mc/sec: 3655.76
//
Query:       EEA22559.1  [L=140]
Description: hypothetical protein PMAA_091860 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (140 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       398  (0.0221987); expected 358.6 (0.02)
Passed bias filter:                      226  (0.0126053); expected 358.6 (0.02)
Passed Vit filter:                         8  (0.000446204); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.30s 00:00:00.76 Elapsed: 00:00:00.48
# Mc/sec: 879.97
//
Query:       EEA22560.1  [L=285]
Description: branched-chain amino acid aminotransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.3e-14   52.4   0.0    8.8e-14   51.9   0.0    1.1  1  Aminotran_4  Amino-transferase class IV


Domain annotation for each model (and alignments):
>> Aminotran_4  Amino-transferase class IV
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.9   0.0   4.9e-18   8.8e-14       3     111 ..      60     171 ..      58     176 .. 0.89

  Alignments for each domain:
  == domain 1  score: 51.9 bits;  conditional E-value: 4.9e-18
  Aminotran_4   3 fEtmrvyngeiffldeHleRLrksaellglelpfdeeelrkileelleannsengrlrllvsrgggglg....aatsepsvavyvsalppgpesekel 96 
                  +++  v +g+ f+ldeHl+RL+ s++ l l+lpf++ee+++il +++ + + + + ++l+v+rg  g +     +  +++++++++++ +  e+e++ 
   EEA22560.1  60 YDVPSVWDGRFFRLDEHLARLQTSCKKLRLQLPFPKEEVKRILVDMVSKSGIRDAFVELIVTRGLKGVRgsepGEVFKNNLYMFIQPFVWVIEPEMQ- 156
                  5666789**********************************************************9999998767789*******************. PP

  Aminotran_4  97 plvtssdvrrdapsp 111
                  p + +++v+r++++ 
   EEA22560.1 157 PTGGKAVVARTVKRA 171
                  666555577777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (285 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       255  (0.0142228); expected 358.6 (0.02)
Passed bias filter:                      248  (0.0138323); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 1946.94
//
Query:       EEA22561.1  [L=841]
Description: transcriptional corepressor Cyc8, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.7e-50  165.8  29.2    5.4e-08   32.3   0.1   11.3 11  TPR_1     Tetratricopeptide repeat
    1.6e-45  149.5  20.9    1.9e-05   24.4   0.0   10.8 11  TPR_2     Tetratricopeptide repeat
    1.8e-36  121.3  19.1    6.8e-05   22.8   0.0   10.9 10  TPR_8     Tetratricopeptide repeat
    1.6e-26   90.7  10.9    5.9e-05   23.5   0.1    8.9  9  TPR_14    Tetratricopeptide repeat
    2.5e-26   90.1  15.1    0.00039   20.6   0.1   10.0 10  TPR_17    Tetratricopeptide repeat
    1.2e-25   88.9  28.3    3.4e-06   26.6   0.2   10.0 10  TPR_11    TPR repeat
    3.4e-25   88.4   6.7    5.2e-05   23.8   0.1    6.6  7  TPR_16    Tetratricopeptide repeat
    1.2e-24   86.6  16.1    0.00011   22.7   0.1    7.4  7  TPR_19    Tetratricopeptide repeat
    1.9e-22   79.3  20.0    4.2e-05   23.7   0.9    7.8  7  TPR_12    Tetratricopeptide repeat
    7.5e-21   73.3  18.4     0.0017   18.9   0.0   10.0 10  TPR_6     Tetratricopeptide repeat
      2e-18   65.0  15.8     0.0094   15.9   0.1    9.1  9  TPR_7     Tetratricopeptide repeat
    3.6e-16   59.1  12.3    0.00063   19.8   0.5    7.0  8  TPR_9     Tetratricopeptide repeat
    2.3e-13   50.2  12.6    2.1e-08   34.3   2.8    4.0  4  ANAPC3    Anaphase-promoting complex, cyclosome, subunit 3
    2.2e-08   33.6  10.5      0.013   14.7   1.5    5.8  3  TPR_15    Tetratricopeptide repeat
    1.8e-06   27.8   5.8      0.019   14.7   0.0    4.1  3  TPR_21    Tetratricopeptide repeat-like domain
    3.1e-06   27.7   6.7       0.01   16.2   0.1    3.4  3  BTAD      Bacterial transcriptional activator domain
     0.0018   17.7   5.7       0.04   13.3   0.1    3.7  4  TPR_MalT  MalT-like TPR region
  ------ inclusion threshold ------
      0.015   15.1   4.8        1.2    8.8   0.0    2.7  2  DUF2225   Uncharacterized protein conserved in bacteria (DUF2
      0.076   13.3   4.0       0.67   10.3   0.0    3.9  4  TPR_20    Tetratricopeptide repeat
        1.3    9.2  19.4         14    5.8   1.8    5.8  6  MIT       MIT (microtubule interacting and transport) domain


Domain annotation for each model (and alignments):
>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.5   0.0    0.0089         8       3      31 ..      54      82 ..      53      84 .. 0.87
   2 !   15.2   0.0   1.6e-05     0.014      15      33 ..     100     118 ..      97     119 .. 0.91
   3 !   19.0   0.0     1e-06   0.00091       2      29 ..     121     148 ..     120     152 .. 0.93
   4 !   17.4   0.0   3.1e-06    0.0028       1      34 []     156     189 ..     156     189 .. 0.95
   5 !   17.5   0.4   2.9e-06    0.0026       2      25 ..     194     217 ..     194     218 .. 0.95
   6 !   25.6   0.0   7.9e-09   7.1e-06       2      34 .]     231     263 ..     230     263 .. 0.96
   7 ?   -0.2   0.1       1.2   1.1e+03       1      14 [.     264     277 ..     264     278 .. 0.90
   8 ?    2.0   0.1      0.23     2e+02      18      31 ..     285     298 ..     284     301 .. 0.82
   9 !   28.6   1.3   8.9e-10   7.9e-07       1      31 [.     302     332 ..     302     335 .. 0.92
  10 !   32.3   0.1     6e-11   5.4e-08       3      32 ..     338     367 ..     336     368 .. 0.96
  11 !   11.8   0.2   0.00019      0.17       2      34 .]     371     404 ..     370     404 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0089
                HHHHHHHHHHHTT-HHHHHHHHHHHHHHS CS
       TPR_1  3 alynlGnayfklgkydeAleyyekALeln 31
                ++ ++G +   +g++d   ++ye+AL++n
  EEA22561.1 54 VWLQIGSLTELMGDLDGGMAAYEQALRHN 82
                57777888889***************998 PP

  == domain 2  score: 15.2 bits;  conditional E-value: 1.6e-05
                 T-HHHHHHHHHHHHHHSTT CS
       TPR_1  15 gkydeAleyyekALelnPn 33 
                 +++ +A+ey +++L+l+P+
  EEA22561.1 100 EQFPKAIEYLQQVLKLDPQ 118
                 799***************7 PP

  == domain 3  score: 19.0 bits;  conditional E-value: 1e-06
                 HHHHHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_1   2 kalynlGnayfklgkydeAleyyekALe 29 
                 +++  lG++++ + +++eA   y++AL 
  EEA22561.1 121 ETWGSLGHCHLMMDNLQEAYTSYQQALY 148
                 68************************96 PP

  == domain 4  score: 17.4 bits;  conditional E-value: 3.1e-06
                 HHHHHHHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1   1 akalynlGnayfklgkydeAleyyekALelnPnn 34 
                 +k +y++G +y + g +d A+e+++++ +  P++
  EEA22561.1 156 PKLWYGIGILYDRYGSLDHAEEAFSQVMRMAPDF 189
                 589**************************99996 PP

  == domain 5  score: 17.5 bits;  conditional E-value: 2.9e-06
                 HHHHHHHHHHHHTT-HHHHHHHHH CS
       TPR_1   2 kalynlGnayfklgkydeAleyye 25 
                 +++++lG +y +++k+++ le+++
  EEA22561.1 194 EIYFRLGIIYKQQQKFNQSLECFK 217
                 58*********************7 PP

  == domain 6  score: 25.6 bits;  conditional E-value: 7.9e-09
                 HHHHHHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1   2 kalynlGnayfklgkydeAleyyekALelnPnn 34 
                 ++++++G+++ +++++d A ++y+++L  +Pn+
  EEA22561.1 231 DIYFQIGHVHEQQKDFDAAQAAYRRVLDKDPNH 263
                 68*****************************97 PP

  == domain 7  score: -0.2 bits;  conditional E-value: 1.2
                 HHHHHHHHHHHHHT CS
       TPR_1   1 akalynlGnayfkl 14 
                 ak+l +lG +y+++
  EEA22561.1 264 AKVLQQLGWLYHQQ 277
                 789999******98 PP

  == domain 8  score: 2.0 bits;  conditional E-value: 0.23
                 HHHHHHHHHHHHHS CS
       TPR_1  18 deAleyyekALeln 31 
                 ++A+ey ek ++ +
  EEA22561.1 285 EKAIEYLEKSVSAD 298
                 89*******98765 PP

  == domain 9  score: 28.6 bits;  conditional E-value: 8.9e-10
                 HHHHHHHHHHHHHTT-HHHHHHHHHHHHHHS CS
       TPR_1   1 akalynlGnayfklgkydeAleyyekALeln 31 
                 a+++y lG +y++++ky +A e+y++A+  +
  EEA22561.1 302 AQSWYLLGRCYMSQQKYPKAYEAYQQAVYRD 332
                 789************************9876 PP

  == domain 10  score: 32.3 bits;  conditional E-value: 6e-11
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHST CS
       TPR_1   3 alynlGnayfklgkydeAleyyekALelnP 32 
                  ++ +G++y++ ++y +Al++y++A++lnP
  EEA22561.1 338 FWCSIGVLYYQINQYRDALDAYSRAIRLNP 367
                 5****************************9 PP

  == domain 11  score: 11.8 bits;  conditional E-value: 0.00019
                 HHHHHHHHHHHHT.T-HHHHHHHHHHHHHHSTTH CS
       TPR_1   2 kalynlGnayfkl.gkydeAleyyekALelnPnn 34 
                 +++y lG +y +  ++  +Al++y +A  l+P+n
  EEA22561.1 371 EVWYDLGTLYESCnNQTADALDAYGRAADLDPTN 404
                 789999999998615799**************98 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0     0.053        47      12      31 ..      63      82 ..      53      83 .. 0.80
   2 !   14.8   0.0   2.5e-05     0.023       7      33 ..      92     118 ..      87     119 .. 0.86
   3 !   14.1   0.0   4.1e-05     0.037       2      28 ..     121     147 ..     120     152 .. 0.91
   4 !   13.2   0.0     8e-05     0.072       1      33 [.     156     188 ..     156     189 .. 0.95
   5 !   14.6   0.0     3e-05     0.027       2      25 ..     194     217 ..     193     220 .. 0.94
   6 !   23.9   0.0     3e-08   2.7e-05       3      34 .]     232     263 ..     230     263 .. 0.96
   7 ?   -1.4   0.1       3.9   3.5e+03       1      14 [.     264     277 ..     264     277 .. 0.87
   8 ?    3.2   0.1      0.13   1.2e+02      18      34 .]     285     301 ..     284     301 .. 0.89
   9 !   24.3   1.1   2.3e-08   2.1e-05       1      31 [.     302     332 ..     302     335 .. 0.90
  10 !   24.4   0.0   2.1e-08   1.9e-05       3      32 ..     338     367 ..     336     369 .. 0.94
  11 !   16.7   0.0   6.3e-06    0.0057       2      34 .]     371     404 ..     370     404 .. 0.97

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.053
       TPR_2 12 yklgdyeeAleafekAleld 31
                + +gd++   +a+e+Al+++
  EEA22561.1 63 ELMGDLDGGMAAYEQALRHN 82
                6789*************987 PP

  == domain 2  score: 14.8 bits;  conditional E-value: 2.5e-05
       TPR_2   7 lGlayyklgdyeeAleafekAleldPn 33 
                 + ++ + + ++ +A+e+++++l+ldP+
  EEA22561.1  92 ISQIMRTREQFPKAIEYLQQVLKLDPQ 118
                 667778889*****************7 PP

  == domain 3  score: 14.1 bits;  conditional E-value: 4.1e-05
       TPR_2   2 ealynlGlayyklgdyeeAleafekAl 28 
                 e +  lG +++ +++++eA   +++Al
  EEA22561.1 121 ETWGSLGHCHLMMDNLQEAYTSYQQAL 147
                 67889*********************9 PP

  == domain 4  score: 13.2 bits;  conditional E-value: 8e-05
       TPR_2   1 aealynlGlayyklgdyeeAleafekAleldPn 33 
                 ++++y +G +y + g ++ A+eaf ++ + +P+
  EEA22561.1 156 PKLWYGIGILYDRYGSLDHAEEAFSQVMRMAPD 188
                 589***************************998 PP

  == domain 5  score: 14.6 bits;  conditional E-value: 3e-05
       TPR_2   2 ealynlGlayyklgdyeeAleafe 25 
                 e++++lG +y +++++++ le+f+
  EEA22561.1 194 EIYFRLGIIYKQQQKFNQSLECFK 217
                 79*********************7 PP

  == domain 6  score: 23.9 bits;  conditional E-value: 3e-08
       TPR_2   3 alynlGlayyklgdyeeAleafekAleldPnn 34 
                 +++++G ++++++d++ A +a++++l  dPn+
  EEA22561.1 232 IYFQIGHVHEQQKDFDAAQAAYRRVLDKDPNH 263
                 79****************************97 PP

  == domain 7  score: -1.4 bits;  conditional E-value: 3.9
       TPR_2   1 aealynlGlayykl 14 
                 a++l +lG++y ++
  EEA22561.1 264 AKVLQQLGWLYHQQ 277
                 68999******986 PP

  == domain 8  score: 3.2 bits;  conditional E-value: 0.13
       TPR_2  18 eeAleafekAleldPnn 34 
                 e+A+e++ek+++ d n+
  EEA22561.1 285 EKAIEYLEKSVSADNND 301
                 89********9999875 PP

  == domain 9  score: 24.3 bits;  conditional E-value: 2.3e-08
       TPR_2   1 aealynlGlayyklgdyeeAleafekAleld 31 
                 a+ +y lG++y+ +++y +A ea+++A+  d
  EEA22561.1 302 AQSWYLLGRCYMSQQKYPKAYEAYQQAVYRD 332
                 678************************8665 PP

  == domain 10  score: 24.4 bits;  conditional E-value: 2.1e-08
       TPR_2   3 alynlGlayyklgdyeeAleafekAleldP 32 
                  ++ +G +yy+ ++y +Al+a+ +A++l+P
  EEA22561.1 338 FWCSIGVLYYQINQYRDALDAYSRAIRLNP 367
                 7999*************************9 PP

  == domain 11  score: 16.7 bits;  conditional E-value: 6.3e-06
       TPR_2   2 ealynlGlayyklgdy.eeAleafekAleldPnn 34 
                 e++y lG +y+  ++  ++Al+a+ +A  ldP+n
  EEA22561.1 371 EVWYDLGTLYESCNNQtADALDAYGRAADLDPTN 404
                 89******************************98 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.7   0.0   0.00057      0.51       2      29 ..      53      80 ..      52      82 .. 0.95
   2 !    9.8   0.0    0.0011         1       6      33 ..      91     118 ..      86     119 .. 0.77
   3 !    7.6   0.1    0.0055       4.9       2      28 ..     121     147 ..     120     148 .. 0.94
   4 !   11.5   0.0   0.00031      0.27       2      33 ..     157     188 ..     156     189 .. 0.95
   5 !   10.5   0.1   0.00065      0.58       2      25 ..     194     217 ..     194     217 .. 0.95
   6 !   22.8   0.0   7.6e-08   6.8e-05       2      34 .]     231     263 ..     230     263 .. 0.93
   7 !    9.1   0.8    0.0019       1.7       3      34 .]     266     301 ..     264     301 .. 0.68
   8 !   19.4   0.6   8.9e-07    0.0008       1      31 [.     302     332 ..     302     335 .. 0.94
   9 !   14.8   0.0   2.8e-05     0.025       3      32 ..     338     367 ..     336     368 .. 0.96
  10 !    7.0   0.0    0.0085       7.6       2      34 .]     371     404 ..     370     404 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00057
                CHHHHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8  2 eayynlgsiylklgdyeeAkeyyekale 29
                ++++++gs+ + +gd++  +++ye+al+
  EEA22561.1 53 QVWLQIGSLTELMGDLDGGMAAYEQALR 80
                69************************95 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.0011
                 HHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   6 nlgsiylklgdyeeAkeyyekaleldpd 33 
                  +++i ++ +++ +A+ey++++l+ldp+
  EEA22561.1  91 AISQIMRTREQFPKAIEYLQQVLKLDPQ 118
                 55666666667779*************7 PP

  == domain 3  score: 7.6 bits;  conditional E-value: 0.0055
                 CHHHHHHHHHHHTT-HHHHHHHHHHHH CS
       TPR_8   2 eayynlgsiylklgdyeeAkeyyekal 28 
                 e +  lg+++l + +++eA  +y++al
  EEA22561.1 121 ETWGSLGHCHLMMDNLQEAYTSYQQAL 147
                 6899**********************8 PP

  == domain 4  score: 11.5 bits;  conditional E-value: 0.00031
                 CHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   2 eayynlgsiylklgdyeeAkeyyekaleldpd 33 
                 +++y +g +y+  g ++ A+e++ ++ +++pd
  EEA22561.1 157 KLWYGIGILYDRYGSLDHAEEAFSQVMRMAPD 188
                 78****************************98 PP

  == domain 5  score: 10.5 bits;  conditional E-value: 0.00065
                 CHHHHHHHHHHHTT-HHHHHHHHH CS
       TPR_8   2 eayynlgsiylklgdyeeAkeyye 25 
                 e+y++lg iy+++++++++ e+++
  EEA22561.1 194 EIYFRLGIIYKQQQKFNQSLECFK 217
                 68********************96 PP

  == domain 6  score: 22.8 bits;  conditional E-value: 7.6e-08
                 CHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH. CS
       TPR_8   2 eayynlgsiylklgdyeeAkeyyekaleldpdn 34 
                 ++y+++g+++++++d+++A+++y+++l+ dp++
  EEA22561.1 231 DIYFQIGHVHEQQKDFDAAQAAYRRVLDKDPNH 263
                 68*************************988876 PP

  == domain 7  score: 9.1 bits;  conditional E-value: 0.0019
                 HHHHHHHHHHHT....T-HHHHHHHHHHHHHHHHH. CS
       TPR_8   3 ayynlgsiylkl....gdyeeAkeyyekaleldpdn 34 
                 ++++lg++y+++       e+A+ey+ek +++d ++
  EEA22561.1 266 VLQQLGWLYHQQstsyASQEKAIEYLEKSVSADNND 301
                 55666666655522223579************9885 PP

  == domain 8  score: 19.4 bits;  conditional E-value: 8.9e-07
                 CCHHHHHHHHHHHTT-HHHHHHHHHHHHHHH CS
       TPR_8   1 aeayynlgsiylklgdyeeAkeyyekaleld 31 
                 a+++y+lg++y+++++y +A e+y++a++ d
  EEA22561.1 302 AQSWYLLGRCYMSQQKYPKAYEAYQQAVYRD 332
                 799*************************987 PP

  == domain 9  score: 14.8 bits;  conditional E-value: 2.8e-05
                 HHHHHHHHHHHTT-HHHHHHHHHHHHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAkeyyekaleldp 32 
                  ++ +g +y + ++y  A  +y +a++l+p
  EEA22561.1 338 FWCSIGVLYYQINQYRDALDAYSRAIRLNP 367
                 69***************************9 PP

  == domain 10  score: 7.0 bits;  conditional E-value: 0.0085
                 CHHHHHHHHH.HHTT-HHHHHHHHHHHHHHHHH. CS
       TPR_8   2 eayynlgsiy.lklgdyeeAkeyyekaleldpdn 34 
                 e++y lg +y +  ++   A  +y +a +ldp+n
  EEA22561.1 371 EVWYDLGTLYeSCNNQTADALDAYGRAADLDPTN 404
                 89********444566778999999999999975 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.0     0.002       1.8       3      34 ..      54      85 ..      52      95 .. 0.84
   2 !   14.0   0.0   7.7e-05     0.069       7      42 ..      92     127 ..      87     129 .. 0.88
   3 ?   -1.7   0.0       8.6   7.7e+03      10      28 ..     129     147 ..     125     154 .. 0.80
   4 !   11.3   0.0   0.00055      0.49       1      43 [.     156     198 ..     156     202 .. 0.90
   5 !   23.5   0.1   6.6e-08   5.9e-05       4      42 ..     233     271 ..     230     273 .. 0.93
   6 !    7.8   0.0    0.0078         7      18      44 .]     285     311 ..     281     311 .. 0.94
   7 !    7.9   0.0    0.0072       6.5       2      38 ..     303     339 ..     302     345 .. 0.86
   8 !   13.8   0.0     9e-05     0.081       9      43 ..     344     378 ..     336     379 .. 0.89
   9 !   14.0   0.1   7.7e-05     0.069       2      41 ..     371     413 ..     370     416 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.002
      TPR_14  3 allalaeallalGdpdeAiallrralalaPdd 34
                ++l+++++ +  Gd+d+ +a++++al+++ ++
  EEA22561.1 54 VWLQIGSLTELMGDLDGGMAAYEQALRHNQWS 85
                799999999******************98655 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 7.7e-05
      TPR_14   7 laeallalGdpdeAiallrralalaPddaeawllla 42 
                 + +++++++++ +Ai++l+++l+l+P++ e+w  l+
  EEA22561.1  92 ISQIMRTREQFPKAIEYLQQVLKLDPQSGETWGSLG 127
                 5688999***********************997665 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 8.6
      TPR_14  10 allalGdpdeAiallrral 28 
                  +l  ++++eA + +++al
  EEA22561.1 129 CHLMMDNLQEAYTSYQQAL 147
                 5666789999999999986 PP

  == domain 4  score: 11.3 bits;  conditional E-value: 0.00055
      TPR_14   1 peallalaeallalGdpdeAiallrralalaPddaeawlllaq 43 
                 p++++ ++ ++ + G +d A++++ ++ + aPd++ a+  + +
  EEA22561.1 156 PKLWYGIGILYDRYGSLDHAEEAFSQVMRMAPDFEKANEIYFR 198
                 689*******************************988766555 PP

  == domain 5  score: 23.5 bits;  conditional E-value: 6.6e-08
      TPR_14   4 llalaeallalGdpdeAiallrralalaPddaeawllla 42 
                 + +++++++++ d+d+A a++rr+l+++P++a ++ +l+
  EEA22561.1 233 YFQIGHVHEQQKDFDAAQAAYRRVLDKDPNHAKVLQQLG 271
                 7799******************************99997 PP

  == domain 6  score: 7.8 bits;  conditional E-value: 0.0078
      TPR_14  18 deAiallrralalaPddaeawlllaql 44 
                 ++Ai++l++ ++++ +da+ w+ll+++
  EEA22561.1 285 EKAIEYLEKSVSADNNDAQSWYLLGRC 311
                 79**********************986 PP

  == domain 7  score: 7.9 bits;  conditional E-value: 0.0072
      TPR_14   2 eallalaeallalGdpdeAiallrralalaPddaeaw 38 
                 + +++l++ ++ ++++ +A +++++a+ ++  ++++w
  EEA22561.1 303 QSWYLLGRCYMSQQKYPKAYEAYQQAVYRDGRNPTFW 339
                 57***********************986666666666 PP

  == domain 8  score: 13.8 bits;  conditional E-value: 9e-05
      TPR_14   9 eallalGdpdeAiallrralalaPddaeawlllaq 43 
                  ++++  ++++A++++ ra++l+P   e+w+ l+ 
  EEA22561.1 344 VLYYQINQYRDALDAYSRAIRLNPYISEVWYDLGT 378
                 5788889***********************99986 PP

  == domain 9  score: 14.0 bits;  conditional E-value: 7.7e-05
      TPR_14   2 eallalaealla.lGdpdeAiallrralalaPdda..eawlll 41 
                 e++++l+ +++  + ++++A++++ ra +l+P++    a+l+l
  EEA22561.1 371 EVWYDLGTLYEScNNQTADALDAYGRAADLDPTNVhiKARLQL 413
                 78********9735789****************9723455655 PP

>> TPR_17  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.0     0.029        26       1      34 []      74     107 ..      74     107 .. 0.93
   2 !    9.9   0.0    0.0011         1       2      32 ..     109     139 ..     108     140 .. 0.94
   3 ?    2.9   0.0      0.19   1.7e+02       2      27 ..     143     170 ..     142     178 .. 0.80
   4 ?    0.3   0.0       1.3   1.2e+03      15      31 ..     195     211 ..     194     214 .. 0.80
   5 ?    0.3   0.0       1.3   1.2e+03      14      33 ..     231     250 ..     230     251 .. 0.92
   6 !   18.7   0.0   1.8e-06    0.0016       1      26 [.     252     277 ..     252     287 .. 0.91
   7 !   15.4   0.3   2.1e-05     0.018       2      32 ..     291     321 ..     290     323 .. 0.92
   8 !   13.9   0.1   5.9e-05     0.053       1      33 [.     324     356 ..     324     357 .. 0.96
   9 !   20.6   0.1   4.4e-07   0.00039       2      33 ..     359     391 ..     358     392 .. 0.88
  10 ?    1.5   0.0      0.55   4.9e+02       2      13 ..     394     405 ..     393     420 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.029
      TPR_17   1 lylkaleldPnnadaynnLAelllknGdlmtArq 34 
                 +y++al+++  + +a++   ++++ + ++ +A++
  EEA22561.1  74 AYEQALRHNQWSIPAMTAISQIMRTREQFPKAIE 107
                 5************************999999975 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.0011
      TPR_17   2 ylkaleldPnnadaynnLAelllknGdlmtA 32 
                 ++++l+ldP + + +  L+ ++l+  +l++A
  EEA22561.1 109 LQQVLKLDPQSGETWGSLGHCHLMMDNLQEA 139
                 6899**********************99998 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.19
      TPR_17   2 ylkalel..dPnnadaynnLAelllknG 27 
                 y++al +  dP+ +++++  + l+ + G
  EEA22561.1 143 YQQALYHlrDPKEPKLWYGIGILYDRYG 170
                 777777777***************8766 PP

  == domain 4  score: 0.3 bits;  conditional E-value: 1.3
      TPR_17  15 aynnLAelllknGdlmt 31 
                  y+ L+ +++++ ++ +
  EEA22561.1 195 IYFRLGIIYKQQQKFNQ 211
                 79********8877655 PP

  == domain 5  score: 0.3 bits;  conditional E-value: 1.3
      TPR_17  14 daynnLAelllknGdlmtAr 33 
                 d y++ + ++++++d++ A+
  EEA22561.1 231 DIYFQIGHVHEQQKDFDAAQ 250
                 68***************998 PP

  == domain 6  score: 18.7 bits;  conditional E-value: 1.8e-06
      TPR_17   1 lylkaleldPnnadaynnLAelllkn 26 
                 +y+++l++dPn+a+++++L++l++++
  EEA22561.1 252 AYRRVLDKDPNHAKVLQQLGWLYHQQ 277
                 59*********************864 PP

  == domain 7  score: 15.4 bits;  conditional E-value: 2.1e-05
      TPR_17   2 ylkaleldPnnadaynnLAelllknGdlmtA 32 
                 ++k++  d n+a ++++L++++ ++ ++ +A
  EEA22561.1 291 LEKSVSADNNDAQSWYLLGRCYMSQQKYPKA 321
                 799*********************9999887 PP

  == domain 8  score: 13.9 bits;  conditional E-value: 5.9e-05
      TPR_17   1 lylkaleldPnnadaynnLAelllknGdlmtAr 33 
                 +y++a+ +d  n+ +++  ++l+++++++++A+
  EEA22561.1 324 AYQQAVYRDGRNPTFWCSIGVLYYQINQYRDAL 356
                 59*****************************96 PP

  == domain 9  score: 20.6 bits;  conditional E-value: 4.4e-07
      TPR_17   2 ylkaleldPnnadaynnLAelll.knGdlmtAr 33 
                 y +a++l+P  +++++ L++l++  n+++++A+
  EEA22561.1 359 YSRAIRLNPYISEVWYDLGTLYEsCNNQTADAL 391
                 99********************73777999986 PP

  == domain 10  score: 1.5 bits;  conditional E-value: 0.55
      TPR_17   2 ylkaleldPnna 13 
                 y +a++ldP+n+
  EEA22561.1 394 YGRAADLDPTNV 405
                 889*******97 PP

>> TPR_11  TPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0      0.25   2.2e+02       8      22 ..      66      80 ..      64      83 .. 0.87
   2 !   12.9   0.0   7.2e-05     0.065       7      38 ..      99     130 ..      94     134 .. 0.85
   3 ?    5.6   0.6     0.014        13       9      38 ..     135     166 ..     133     170 .. 0.85
   4 ?    3.7   0.0     0.057        51      29      41 ..     194     206 ..     190     217 .. 0.76
   5 ?    1.8   0.0      0.21   1.9e+02      29      41 ..     231     243 ..     229     244 .. 0.91
   6 !   16.4   0.5   6.1e-06    0.0055       1      41 [.     237     277 ..     237     278 .. 0.93
   7 !    9.2   0.1    0.0011      0.99      10      40 ..     284     314 ..     283     315 .. 0.91
   8 !   26.6   0.2   3.8e-09   3.4e-06       1      40 [.     309     348 ..     309     350 .. 0.95
   9 !   23.1   1.5   4.7e-08   4.2e-05       4      39 ..     346     381 ..     345     382 .. 0.95
  10 !    9.9   0.1   0.00065      0.58       8      28 ..     385     405 ..     384     408 .. 0.90

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.25
      TPR_11  8 GkyeeAieaYkkAlk 22
                G++++ ++aY++Al+
  EEA22561.1 66 GDLDGGMAAYEQALR 80
                999999*******97 PP

  == domain 2  score: 12.9 bits;  conditional E-value: 7.2e-05
      TPR_11   7 qGkyeeAieaYkkAlkldPdnaeayynLGlay 38 
                 + ++++Aie +++ lkldP++ e +  LG+ +
  EEA22561.1  99 REQFPKAIEYLQQVLKLDPQSGETWGSLGHCH 130
                 789*****************999998888766 PP

  == domain 3  score: 5.6 bits;  conditional E-value: 0.014
      TPR_11   9 kyeeAieaYkkAlkl..dPdnaeayynLGlay 38 
                 ++ eA ++Y++Al    dP+ + ++y++G +y
  EEA22561.1 135 NLQEAYTSYQQALYHlrDPKEPKLWYGIGILY 166
                 578999******97445999999999999988 PP

  == domain 4  score: 3.7 bits;  conditional E-value: 0.057
      TPR_11  29 eayynLGlayykq 41 
                 e+y+ LG +y +q
  EEA22561.1 194 EIYFRLGIIYKQQ 206
                 6788888888776 PP

  == domain 5  score: 1.8 bits;  conditional E-value: 0.21
      TPR_11  29 eayynLGlayykq 41 
                 ++y+ +G+++ +q
  EEA22561.1 231 DIYFQIGHVHEQQ 243
                 8*********998 PP

  == domain 6  score: 16.4 bits;  conditional E-value: 6.1e-06
      TPR_11   1 GdayyeqGkyeeAieaYkkAlkldPdnaeayynLGlayykq 41 
                 G++  +q ++++A +aY++ l+ dP+ a ++  LG +y++q
  EEA22561.1 237 GHVHEQQKDFDAAQAAYRRVLDKDPNHAKVLQQLGWLYHQQ 277
                 56666999*******************************98 PP

  == domain 7  score: 9.2 bits;  conditional E-value: 0.0011
      TPR_11  10 yeeAieaYkkAlkldPdnaeayynLGlayyk 40 
                  e+Aie ++k +  d+++a  +y LG  y+ 
  EEA22561.1 284 QEKAIEYLEKSVSADNNDAQSWYLLGRCYMS 314
                 599***********************88765 PP

  == domain 8  score: 26.6 bits;  conditional E-value: 3.8e-09
      TPR_11   1 GdayyeqGkyeeAieaYkkAlkldPdnaeayynLGlayyk 40 
                 G+ y++q+ky++A eaY++A+  d  n+++++ +G++yy+
  EEA22561.1 309 GRCYMSQQKYPKAYEAYQQAVYRDGRNPTFWCSIGVLYYQ 348
                 677************************************8 PP

  == domain 9  score: 23.1 bits;  conditional E-value: 4.7e-08
      TPR_11   4 yyeqGkyeeAieaYkkAlkldPdnaeayynLGlayy 39 
                 yy+ ++y +A+ aY++A++l+P   e++y LG +y 
  EEA22561.1 346 YYQINQYRDALDAYSRAIRLNPYISEVWYDLGTLYE 381
                 9*******************************9985 PP

  == domain 10  score: 9.9 bits;  conditional E-value: 0.00065
      TPR_11   8 GkyeeAieaYkkAlkldPdna 28 
                 ++  +A+ aY +A +ldP+n+
  EEA22561.1 385 NQTADALDAYGRAADLDPTNV 405
                 68889**************97 PP

>> TPR_16  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0      0.95   8.5e+02      11      27 ..      66      82 ..      64      83 .. 0.75
   2 !   12.7   0.0   0.00018      0.16      10      61 ..      99     147 ..      97     156 .. 0.86
   3 ?    5.9   0.1     0.022        20      15      66 ..     138     188 ..     135     188 .. 0.78
   4 !    7.8   0.0    0.0059       5.3      11      48 ..     170     207 ..     160     223 .. 0.87
   5 !   23.0   0.5     1e-07   9.1e-05       3      59 ..     236     293 ..     234     301 .. 0.82
   6 !   18.0   0.1   3.9e-06    0.0035      15      62 ..     286     330 ..     285     336 .. 0.80
   7 !   23.8   0.1   5.8e-08   5.2e-05       4      66 ..     343     403 ..     340     405 .. 0.85

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.95
      TPR_16 11 gdyddAaaaleaalkrd 27
                gd d   aa+e+al+ +
  EEA22561.1 66 GDLDGGMAAYEQALRHN 82
                77777888888888765 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 0.00018
      TPR_16  10 agdyddAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraal 61 
                 + ++++A+++l+++lk+d   P+  e +  lg ++l   +l+eA   y+ al
  EEA22561.1  99 REQFPKAIEYLQQVLKLD---PQSGETWGSLGHCHLMMDNLQEAYTSYQQAL 147
                 57899*************...***************9999999986665555 PP

  == domain 3  score: 5.9 bits;  conditional E-value: 0.022
      TPR_16  15 dAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraalraapd 66 
                 +A   +++al    ++P  +  +++ g ++ r g l+ A++++    r apd
  EEA22561.1 138 EAYTSYQQALYHL-RDPKEPKLWYGIGILYDRYGSLDHAEEAFSQVMRMAPD 188
                 5556665555333.68999*********************999887777775 PP

  == domain 4  score: 7.8 bits;  conditional E-value: 0.0059
      TPR_16  11 gdyddAaaaleaalkrdpssPdaaeAllllgdaalrqg 48 
                 g  d A++a+ ++ +++p+   a e ++ lg ++ +q+
  EEA22561.1 170 GSLDHAEEAFSQVMRMAPDFEKANEIYFRLGIIYKQQQ 207
                 67788************99999***********99886 PP

  == domain 5  score: 23.0 bits;  conditional E-value: 1e-07
      TPR_16   3 laraalragdyddAaaaleaalkrdpssPdaaeAllllgdaalrq....grlaeAaalyra 59 
                  ++ + +++d+d+A+aa++++l++d   P +a  l  lg+++ +q       ++A++++++
  EEA22561.1 236 IGHVHEQQKDFDAAQAAYRRVLDKD---PNHAKVLQQLGWLYHQQstsyASQEKAIEYLEK 293
                 69999********************...**************9996655566666666655 PP

  == domain 6  score: 18.0 bits;  conditional E-value: 3.9e-06
      TPR_16  15 dAaaaleaalkrdpssPdaaeAllllgdaalrqgrlaeAaalyraalr 62 
                 +A+++le  + +d     +a++++llg+++  q+ +++A ++y+ a+ 
  EEA22561.1 286 KAIEYLEKSVSAD---NNDAQSWYLLGRCYMSQQKYPKAYEAYQQAVY 330
                 5667777777777...889*********************99888873 PP

  == domain 7  score: 23.8 bits;  conditional E-value: 5.8e-08
      TPR_16   4 araalragdyddAaaaleaalkrdpssPdaaeAllllgdaal.rqgrlaeAa.alyraalraapd 66 
                 + ++++ ++y+dA+ a+ +a++++   P   e ++ lg ++   ++  a+A+ a+  +a++ +p 
  EEA22561.1 343 GVLYYQINQYRDALDAYSRAIRLN---PYISEVWYDLGTLYEsCNNQTADALdAYG-RAADLDPT 403
                 6689********************...99999**********66789999995555.55599997 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.3   0.0   9.8e-05     0.087       4      60 ..      65     122 ..      64     127 .. 0.90
   2 !   22.3   0.0   1.6e-07   0.00014       4      57 ..      99     152 ..      96     153 .. 0.91
   3 !   18.6   0.1   2.2e-06     0.002       2      57 ..     131     188 ..     130     195 .. 0.92
   4 !    8.5   0.0    0.0031       2.8       5      53 ..     170     221 ..     168     226 .. 0.88
   5 !   17.4   0.5   5.4e-06    0.0048       3      38 ..     242     277 ..     241     278 .. 0.94
   6 !   22.7   0.1   1.2e-07   0.00011       9      57 ..     286     334 ..     284     339 .. 0.90
   7 !   14.4   1.2   4.5e-05     0.041       6      57 ..     351     403 ..     347     417 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 9.8e-05
      TPR_19   4 egdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpdd.ar 60 
                 +gd++  +a++eqal ++  +  a  +  +++    q+ +A++ L+++++ dp++ + 
  EEA22561.1  65 MGDLDGGMAAYEQALRHNQWSIPAMTAISQIMRTREQFPKAIEYLQQVLKLDPQSgET 122
                 7999999*********************************************997555 PP

  == domain 2  score: 22.3 bits;  conditional E-value: 1.6e-07
      TPR_19   4 egdyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpd 57 
                 ++++  A+++l+q+l+ dp+++e +  L  ++l + +l+eA    ++++ + +d
  EEA22561.1  99 REQFPKAIEYLQQVLKLDPQSGETWGSLGHCHLMMDNLQEAYTSYQQALYHLRD 152
                 579999***********************************9988888766665 PP

  == domain 3  score: 18.6 bits;  conditional E-value: 2.2e-06
      TPR_19   2 laegdyaeAlalleqal..qedpknaearllLAeallalgqldeAealLdalpeedpd 57 
                 l++ +++eA   ++qal    dpk + ++++  +++   g ld Ae++ +++++++pd
  EEA22561.1 131 LMMDNLQEAYTSYQQALyhLRDPKEPKLWYGIGILYDRYGSLDHAEEAFSQVMRMAPD 188
                 67899***********85566************************************9 PP

  == domain 4  score: 8.5 bits;  conditional E-value: 0.0031
      TPR_19   5 gdyaeAlalleqalqedpk...naearllLAeallalgqldeAealLdalpe 53 
                 g ++ A ++++q++  +p+     e+  +L +++ ++  +++  ++ + + +
  EEA22561.1 170 GSLDHAEEAFSQVMRMAPDfekANEIYFRLGIIYKQQQKFNQSLECFKYIVN 221
                 88999**************888888899**************9999987766 PP

  == domain 5  score: 17.4 bits;  conditional E-value: 5.4e-06
      TPR_19   3 aegdyaeAlalleqalqedpknaearllLAeallal 38 
                 +++d+++A+a+++++l++dp++a ++ +L  ++ ++
  EEA22561.1 242 QQKDFDAAQAAYRRVLDKDPNHAKVLQQLGWLYHQQ 277
                 699**************************9999886 PP

  == domain 6  score: 22.7 bits;  conditional E-value: 1.2e-07
      TPR_19   9 eAlalleqalqedpknaearllLAeallalgqldeAealLdalpeedpd 57 
                  A+++le+  ++d+++a  ++lL ++++++  + +A ++ +++   d  
  EEA22561.1 286 KAIEYLEKSVSADNNDAQSWYLLGRCYMSQQKYPKAYEAYQQAVYRDGR 334
                 79***********************************999998776665 PP

  == domain 7  score: 14.4 bits;  conditional E-value: 4.5e-05
      TPR_19   6 dyaeAlalleqalqedpknaearllLAeallal.gqldeAealLdalpeedpd 57 
                 +y +Al+++++a+  +p  +e++++L  ++ +  +q+++A ++  ++ + dp 
  EEA22561.1 351 QYRDALDAYSRAIRLNPYISEVWYDLGTLYESCnNQTADALDAYGRAADLDPT 403
                 9*******************************999********9999999998 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.0   8.2e-05     0.073      17      76 ..      66     117 ..      51     118 .. 0.74
   2 !   21.1   0.1   3.2e-07   0.00029       4      76 ..     121     187 ..     118     188 .. 0.89
   3 ?    3.8   0.0     0.076        69      47      68 ..     195     216 ..     192     217 .. 0.60
   4 !   18.0   0.8   2.8e-06    0.0025       5      73 ..     232     296 ..     229     300 .. 0.76
   5 !   13.2   0.7   9.2e-05     0.082      27      71 ..     285     328 ..     280     331 .. 0.70
   6 !   23.7   0.9   4.7e-08   4.2e-05       3      74 ..     302     365 ..     300     367 .. 0.87
   7 ?    6.0   0.1     0.017        15      42      75 ..     367     401 ..     366     403 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 8.2e-05
      TPR_12  17 grydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                 g++d   + +e+a       l + + + + ++ +++++ r ++++ +A+e+l+++l++++
  EEA22561.1  66 GDLDGGMAAYEQA-------LRH-NQWSIPAMTAISQIMRTREQFPKAIEYLQQVLKLDP 117
                 5555555555555.......333.347999**************************9976 PP

  == domain 2  score: 21.1 bits;  conditional E-value: 3.2e-07
      TPR_12   4 talnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaiae 76 
                  ++  l+++++ + +++eA + +++al       +p    +    +++g+ly++ g ++ A+e++ +++++a+
  EEA22561.1 121 ETWGSLGHCHLMMDNLQEAYTSYQQALYHL---RDP---KEPKLWYGIGILYDRYGSLDHAEEAFSQVMRMAP 187
                 57888*********************9999...335...46668**************************986 PP

  == domain 3  score: 3.8 bits;  conditional E-value: 0.076
      TPR_12  47 tlrnLgrlyralgryeeAlell 68 
                 +++ Lg++y ++ ++ + le +
  EEA22561.1 195 IYFRLGIIYKQQQKFNQSLECF 216
                 4566666666666666666655 PP

  == domain 4  score: 18.0 bits;  conditional E-value: 2.8e-06
      TPR_12   5 alnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralg....ryeeAlelleeala 73 
                 ++ ++++v+ +++++d A++ ++++l+       p+h   a +l+ Lg+ly+++      +e+A+e+le+++ 
  EEA22561.1 232 IYFQIGHVHEQQKDFDAAQAAYRRVLDKD-----PNH---AKVLQQLGWLYHQQStsyaSQEKAIEYLEKSVS 296
                 55578999999999999999999996666.....666...99********98875333356788888888876 PP

  == domain 5  score: 13.2 bits;  conditional E-value: 9.2e-05
      TPR_12  27 ekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleea 71 
                 eka+e  +++   d+ + a++ + Lgr+y  + +y +A e++++a
  EEA22561.1 285 EKAIEYLEKSVSADN-NDAQSWYLLGRCYMSQQKYPKAYEAYQQA 328
                 555666655555666.67888888888886666888888888887 PP

  == domain 6  score: 23.7 bits;  conditional E-value: 4.7e-08
      TPR_12   3 atalnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealai 74 
                 a++++ l+ +++ +++y +A e +++a+ +      +      t  + +g ly++ ++y++Al+++ +a+++
  EEA22561.1 302 AQSWYLLGRCYMSQQKYPKAYEAYQQAVYRD-----GR---NPTFWCSIGVLYYQINQYRDALDAYSRAIRL 365
                 677889*********************4444.....44...36799***********************987 PP

  == domain 7  score: 6.0 bits;  conditional E-value: 0.017
      TPR_12  42 pltattlrnLgrly.ralgryeeAlelleealaia 75 
                 p+ +++ ++Lg+ly +  +++++Al+++ +a +++
  EEA22561.1 367 PYISEVWYDLGTLYeSCNNQTADALDAYGRAADLD 401
                 66778899*****966*************998875 PP

>> TPR_6  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0       0.6   5.4e+02       4      28 ..      56      80 ..      53      82 .. 0.78
   2 !    9.7   0.0    0.0016       1.4      14      33 .]     100     119 ..      88     119 .. 0.75
   3 ?    2.8   0.0      0.25   2.2e+02       6      27 ..     126     147 ..     125     148 .. 0.91
   4 ?   -0.5   0.0       2.9   2.6e+03       4      32 ..     160     188 ..     158     188 .. 0.83
   5 ?    4.7   0.0     0.062        56       3      25 ..     196     218 ..     194     223 .. 0.86
   6 !   18.9   0.0   1.9e-06    0.0017       3      33 .]     233     263 ..     231     263 .. 0.94
   7 ?    1.6   0.0       0.6   5.4e+02       5      25 ..     269     293 ..     265     296 .. 0.80
   8 !   16.0   0.6   1.6e-05     0.014       2      28 ..     304     330 ..     303     333 .. 0.90
   9 !   10.2   0.1    0.0011      0.99       6      31 ..     342     367 ..     341     367 .. 0.92
  10 !   10.1   0.0    0.0011         1       1      32 [.     371     403 ..     371     404 .. 0.91

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.6
                HHHHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6  4 yklalsyrklgdtdkAlealerlik 28
                ++++ + + +gd d  ++a+e+ ++
  EEA22561.1 56 LQIGSLTELMGDLDGGMAAYEQALR 80
                66666556689**********9876 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.0016
                 HHHHHHHHHHHHHHHH-TT- CS
       TPR_6  14 gdtdkAlealerlikeYPdS 33 
                  +  kA+e+l++++k  P+S
  EEA22561.1 100 EQFPKAIEYLQQVLKLDPQS 119
                 3888**************98 PP

  == domain 3  score: 2.8 bits;  conditional E-value: 0.25
                 HHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   6 lalsyrklgdtdkAlealerli 27 
                 l+ +++++++ ++A + +++ +
  EEA22561.1 126 LGHCHLMMDNLQEAYTSYQQAL 147
                 789****************975 PP

  == domain 4  score: -0.5 bits;  conditional E-value: 2.9
                 HHHHHHHHHHHHHHHHHHHHHHHHHH-TT CS
       TPR_6   4 yklalsyrklgdtdkAlealerlikeYPd 32 
                 y ++ +y + g  d A ea+ ++ +  Pd
  EEA22561.1 160 YGIGILYDRYGSLDHAEEAFSQVMRMAPD 188
                 89999***977999999999999876665 PP

  == domain 5  score: 4.7 bits;  conditional E-value: 0.062
                 HHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   3 lyklalsyrklgdtdkAlealer 25 
                 +++l+  y+++++  ++le ++ 
  EEA22561.1 196 YFRLGIIYKQQQKFNQSLECFKY 218
                 8*********88*******9975 PP

  == domain 6  score: 18.9 bits;  conditional E-value: 1.9e-06
                 HHHHHHHHHHHHHHHHHHHHHHHHHHH-TT- CS
       TPR_6   3 lyklalsyrklgdtdkAlealerlikeYPdS 33 
                 +++++  +++++d d+A +a++r++++ P++
  EEA22561.1 233 YFQIGHVHEQQKDFDAAQAAYRRVLDKDPNH 263
                 89***************************96 PP

  == domain 7  score: 1.6 bits;  conditional E-value: 0.6
                 HHHHHHHHH....HHHHHHHHHHHH CS
       TPR_6   5 klalsyrkl....gdtdkAlealer 25 
                 +l+++y ++       +kA+e+le+
  EEA22561.1 269 QLGWLYHQQstsyASQEKAIEYLEK 293
                 799999998777767779***9997 PP

  == domain 8  score: 16.0 bits;  conditional E-value: 1.6e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHHHH CS
       TPR_6   2 AlyklalsyrklgdtdkAlealerlik 28 
                 + y+l+++y +++++ kA ea+++ + 
  EEA22561.1 304 SWYLLGRCYMSQQKYPKAYEAYQQAVY 330
                 68*********88***********875 PP

  == domain 9  score: 10.2 bits;  conditional E-value: 0.0011
                 HHHHHHHHHHHHHHHHHHHHHHHH-T CS
       TPR_6   6 lalsyrklgdtdkAlealerlikeYP 31 
                 ++ +y++ +++++Al+a+ r i+  P
  EEA22561.1 342 IGVLYYQINQYRDALDAYSRAIRLNP 367
                 799****88*************9877 PP

  == domain 10  score: 10.1 bits;  conditional E-value: 0.0011
                 HHHHHHHHHHHH.HHHHHHHHHHHHHHHHH-TT CS
       TPR_6   1 dAlyklalsyrk.lgdtdkAlealerlikeYPd 32 
                 ++ y l+ +y++  ++t++Al+a+ r  +  P+
  EEA22561.1 371 EVWYDLGTLYEScNNQTADALDAYGRAADLDPT 403
                 57899*********************9998885 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.0      0.01       9.3      12      32 ..      99     117 ..      88     121 .. 0.76
   2 ?    6.3   0.0     0.013        11       1      32 [.     122     153 ..     122     157 .. 0.81
   3 !    6.9   0.0     0.008       7.1       2      23 ..     196     217 ..     195     222 .. 0.94
   4 !   14.8   0.0   2.3e-05     0.021       2      35 ..     233     264 ..     232     265 .. 0.94
   5 ?   -2.6   0.1       8.8   7.9e+03       2      12 ..     267     277 ..     266     278 .. 0.81
   6 ?    2.1   0.0      0.28   2.5e+02      16      28 ..     285     295 ..     284     302 .. 0.74
   7 !   15.9   0.1     1e-05    0.0094       1      33 [.     304     334 ..     304     337 .. 0.88
   8 !   10.2   0.1   0.00071      0.64       2      34 ..     339     369 ..     339     371 .. 0.91
   9 ?    4.6   0.1     0.043        38       2      34 ..     373     404 ..     372     405 .. 0.89

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.01
       TPR_7  12 lGdyeeAielyeqsLaltkdp 32 
                 + ++ +Aie+++q  +l  dp
  EEA22561.1  99 REQFPKAIEYLQQ--VLKLDP 117
                 56799********..665555 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.013
       TPR_7   1 aLlnLarlysrlGdyeeAielyeqsL.altkdp 32 
                 ++  L++++  + + +eA + y+q+L  l +dp
  EEA22561.1 122 TWGSLGHCHLMMDNLQEAYTSYQQALyHL-RDP 153
                 57889999****************99444.444 PP

  == domain 3  score: 6.9 bits;  conditional E-value: 0.008
       TPR_7   2 LlnLarlysrlGdyeeAielye 23 
                 +++L+ +y +++++ + +e+++
  EEA22561.1 196 YFRLGIIYKQQQKFNQSLECFK 217
                 789*****************97 PP

  == domain 4  score: 14.8 bits;  conditional E-value: 2.3e-05
       TPR_7   2 LlnLarlysrlGdyeeAielyeqsLaltkdpeda 35 
                 +++++++++++ d++ A   y++  +l+kdp++a
  EEA22561.1 233 YFQIGHVHEQQKDFDAAQAAYRR--VLDKDPNHA 264
                 7899*******************..******997 PP

  == domain 5  score: -2.6 bits;  conditional E-value: 8.8
       TPR_7   2 LlnLarlysrl 12 
                 L +L+ ly+++
  EEA22561.1 267 LQQLGWLYHQQ 277
                 77899999987 PP

  == domain 6  score: 2.1 bits;  conditional E-value: 0.28
       TPR_7  16 eeAielyeqsLal 28 
                 e+Aie++e+   +
  EEA22561.1 285 EKAIEYLEK--SV 295
                 89******9..44 PP

  == domain 7  score: 15.9 bits;  conditional E-value: 1e-05
       TPR_7   1 aLlnLarlysrlGdyeeAielyeqsLaltkdpe 33 
                 +++ L+r+y ++++y +A e y+q  a+ +d  
  EEA22561.1 304 SWYLLGRCYMSQQKYPKAYEAYQQ--AVYRDGR 334
                 6899********************..9888765 PP

  == domain 8  score: 10.2 bits;  conditional E-value: 0.00071
       TPR_7   2 LlnLarlysrlGdyeeAielyeqsLaltkdped 34 
                 ++ +++ly + ++y++A++ y +  a++  p++
  EEA22561.1 339 WCSIGVLYYQINQYRDALDAYSR--AIRLNPYI 369
                 5899*******************..99999987 PP

  == domain 9  score: 4.6 bits;  conditional E-value: 0.043
       TPR_7   2 LlnLarlysr.lGdyeeAielyeqsLaltkdped 34 
                 ++ L+ ly++  +++++A++ y +  a + dp++
  EEA22561.1 373 WYDLGTLYEScNNQTADALDAYGR--AADLDPTN 404
                 56799*****99************..99999876 PP

>> TPR_9  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.1      0.33     3e+02      32      59 ..      55      82 ..      53      96 .. 0.86
   2 !   17.1   0.0   4.9e-06    0.0044       3      58 ..      94     149 ..      92     152 .. 0.92
   3 !    8.1   0.0    0.0033         3      24      68 ..     151     195 ..     147     200 .. 0.90
   4 ?   -0.9   0.0       2.1   1.9e+03      35      56 ..     199     220 ..     194     230 .. 0.70
   5 !   12.2   0.2   0.00017      0.15       3      42 ..     238     277 ..     236     304 .. 0.88
   6 !   10.4   0.0   0.00063      0.56      12      61 ..     285     334 ..     279     338 .. 0.91
   7 !   19.8   0.5     7e-07   0.00063       3      60 ..     310     367 ..     308     394 .. 0.88
   8 !   11.3   0.6   0.00031      0.28       4      65 ..     345     407 ..     342     415 .. 0.79

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.33
       TPR_9 32 rrdRGlllaqlGclsaAladLeaylala 59
                ++  G l + +G+l +++a+ e++l+++
  EEA22561.1 55 WLQIGSLTELMGDLDGGMAAYEQALRHN 82
                77889999*****************987 PP

  == domain 2  score: 17.1 bits;  conditional E-value: 4.9e-06
       TPR_9   3 aiaireedweralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylal 58 
                 +i+  +e++++a+++++ +l l+P++ e +   G ++  +++l++A    +++l +
  EEA22561.1  94 QIMRTREQFPKAIEYLQQVLKLDPQSGETWGSLGHCHLMMDNLQEAYTSYQQALYH 149
                 78899******************************************999999855 PP

  == domain 3  score: 8.1 bits;  conditional E-value: 0.0033
       TPR_9  24 laPddpeerrdRGlllaqlGclsaAladLeaylalapdapdaeai 68 
                  +P++p +++  G+l+ + G l  A +++ + +++apd + a  i
  EEA22561.1 151 RDPKEPKLWYGIGILYDRYGSLDHAEEAFSQVMRMAPDFEKANEI 195
                 58***********************************98877665 PP

  == domain 4  score: -0.9 bits;  conditional E-value: 2.1
       TPR_9  35 RGlllaqlGclsaAladLeayl 56 
                  G+++ q+  +++ l+++ + +
  EEA22561.1 199 LGIIYKQQQKFNQSLECFKYIV 220
                 5777888888888888777654 PP

  == domain 5  score: 12.2 bits;  conditional E-value: 0.00017
       TPR_9   3 aiaireedweralavverllllaPddpeerrdRGlllaql 42 
                 +++ +++d+++a a++ r+l  +P+++  +   G l++q+
  EEA22561.1 238 HVHEQQKDFDAAQAAYRRVLDKDPNHAKVLQQLGWLYHQQ 277
                 789**********************************997 PP

  == domain 6  score: 10.4 bits;  conditional E-value: 0.00063
       TPR_9  12 eralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalapd 61 
                 e+a++++e  +  + +d++ ++  G++++ +  + +A ++ ++++  ++ 
  EEA22561.1 285 EKAIEYLEKSVSADNNDAQSWYLLGRCYMSQQKYPKAYEAYQQAVYRDGR 334
                 89****************************************99866655 PP

  == domain 7  score: 19.8 bits;  conditional E-value: 7e-07
       TPR_9   3 aiaireedweralavverllllaPddpeerrdRGlllaqlGclsaAladLeaylalap 60 
                 +++++++++++a ++++  ++ + + p  +   G+l++q ++++ Al++  ++++l+p
  EEA22561.1 310 RCYMSQQKYPKAYEAYQQAVYRDGRNPTFWCSIGVLYYQINQYRDALDAYSRAIRLNP 367
                 689****************************************************999 PP

  == domain 8  score: 11.3 bits;  conditional E-value: 0.00031
       TPR_9   4 iaireedweralavverllllaPddpeerrdRGlllaqlG.clsaAladLeaylalapdapda 65 
                 ++ + +++  al ++ r + l+P   e ++d G l++  + +++ Al++  ++++l+p +  +
  EEA22561.1 345 LYYQINQYRDALDAYSRAIRLNPYISEVWYDLGTLYESCNnQTADALDAYGRAADLDPTNVHI 407
                 5777889999**************************997525777888888888888865544 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.1   0.0   4.7e-05     0.042      26      80 ..      89     144 ..      72     146 .. 0.85
   2 ?    6.5   0.1     0.011        10      20      58 ..     226     266 ..     188     278 .. 0.84
   3 !   34.3   2.8   2.3e-11   2.1e-08       6      81 ..     285     361 ..     280     362 .. 0.96
   4 ?   -1.5   0.1       3.3   2.9e+03       3      38 ..     385     417 ..     384     419 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 4.7e-05
                 HHHHHHHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHHH- CS
      ANAPC3  26 ayllAlclylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaaLe 80 
                   + ++ +  ++q+ +A+e+l++  kl+++s + +  +++c l +++++eA++ ++
  EEA22561.1  89 MTAISQIMRTREQFPKAIEYLQQVlKLDPQSGETWGSLGHCHLMMDNLQEAYTSYQ 144
                 55667889999*****************************************9876 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.011
                 H--HHHHHHH.HHHHHHTT-HHHHHHHHHCT.SHHHC-HHH CS
      ANAPC3  20 tespedayll.AlclylngqykrAyellrka.klnskslgc 58 
                 +  +ed+y+  + ++ ++++++ A+  +r+  ++++++ ++
  EEA22561.1 226 PLTEEDIYFQiGHVHEQQKDFDAAQAAYRRVlDKDPNHAKV 266
                 56789999977********************9999999876 PP

  == domain 3  score: 34.3 bits;  conditional E-value: 2.3e-11
                 HHHHHHHHHHH.HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHHH-S CS
      ANAPC3   6 knAiflaerllaaetespedayllAlclylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaaLek 81 
                 ++Ai ++e+ ++a+++++++ yll+ c+ ++++y +Aye +++a   +++++  +  ++  ++++++y +A++a+++
  EEA22561.1 285 EKAIEYLEKSVSADNNDAQSWYLLGRCYMSQQKYPKAYEAYQQAvYRDGRNPTFWCSIGVLYYQINQYRDALDAYSR 361
                 79***********************************************************************9875 PP

  == domain 4  score: -1.5 bits;  conditional E-value: 3.3
                 T-HHHHHHHHHHHH.HHH--HHHHHHHHHHHHHTT- CS
      ANAPC3   3 nnyknAiflaerllaaetespedayllAlclylngq 38 
                 n++ +A+  + r+      +p +++ +A   +l+gq
  EEA22561.1 385 NQTADALDAYGRAA---DLDPTNVHIKARLQLLQGQ 417
                 67777777777777...8899999999999999998 PP

>> TPR_15  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.9     0.016        14      35     174 ..      44     114 ..      40     208 .. 0.58
   2 !   12.5   0.1   6.9e-05     0.062     120     191 ..     203     275 ..     201     288 .. 0.81
   3 !   14.7   1.5   1.5e-05     0.013      63     186 ..     284     411 ..     281     414 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.016
      TPR_15  35 aqkaapskdteyWrtladLAwalqqedearkAyrqLlasgkaraedyerliel.lydaepkeaarlaekgwrrfrsprlLssalellerakdydriael 132
                 aqk+a + ++++W + + L   + + d + +Ay+q l+ ++ ++  + ++ ++ + ++++ +a+++ ++                              
  EEA22561.1  44 AQKIA-ALNEQVWLQIGSLTELMGDLDGGMAAYEQALRHNQWSIPAMTAISQImRTREQFPKAIEYLQQ------------------------------ 111
                 56664.666666666666666666666666666666666666666666666664445555555555443.............................. PP

      TPR_15 133 lksleeeeaaeqsaafllaraelyrqegqtdaAlrdyreAla 174
                                                        +l+
  EEA22561.1 112 ---------------------------------------VLK 114
                 .......................................333 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 6.9e-05
      TPR_15 120 lerakdydriaellksleeeea.aeqsaafllaraelyrqegqtdaAlrdyreAlalapdsselraallWlli 191
                 +++++++++  e +k++ +++     ++ +++  + +++q+ + daA  +yr++l+++p+ +++ ++l Wl+ 
  EEA22561.1 203 YKQQQKFNQSLECFKYIVNDPPrPLTEEDIYFQIGHVHEQQKDFDAAQAAYRRVLDKDPNHAKVLQQLGWLYH 275
                 566777777777788877655434566777778899**********************************986 PP

  == domain 3  score: 14.7 bits;  conditional E-value: 1.5e-05
      TPR_15  63 arkAyrqLlasgkaraedyerliel.l....ydaepkeaarlaekgwrrfrsprlLssalellerakdydriaellksleeeeaaeqsaafllarae.l 155
                  +kA + L +s  a+ +d+++ ++l +    +++ pk+  ++ ++ +r  r+p ++ s   l+++ ++y+   +   ++ +++ +   + +++ ++  +
  EEA22561.1 284 QEKAIEYLEKSVSADNNDAQSWYLLgRcymsQQKYPKAYEAYQQAVYRDGRNPTFWCSIGVLYYQINQYRDALDAYSRAIRLNPYI--SEVWYDLGTlY 380
                 67899999999999999999999886343434566666677888899999****************99987777777666555554..44666665505 PP

      TPR_15 156 yrqegqtdaAlrdyreAlalapdsselraal 186
                 ++ ++qt++Al +y +A +l+p++  ++a+l
  EEA22561.1 381 ESCNNQTADALDAYGRAADLDPTNVHIKARL 411
                 566889999***************9999986 PP

>> TPR_21  Tetratricopeptide repeat-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.4   0.0    0.0072       6.4     115     178 ..      88     152 ..      51     159 .. 0.76
   2 !   14.7   0.0   2.1e-05     0.019      90     184 ..     170     267 ..     167     274 .. 0.90
   3 !    6.6   0.5    0.0064       5.8     130     177 ..     285     333 ..     277     351 .. 0.82

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.0072
      TPR_21 115 arlRLarvllaekkydeAlktLeakke.eafaalvaelrGDilvaqgkldeAraaYqaAlaalee 178
                 a   + +++   +++ +A++ L+++ + +  +++     G  ++ +++l+eA + Yq+Al +l +
  EEA22561.1  88 AMTAISQIMRTREQFPKAIEYLQQVLKlDPQSGETWGSLGHCHLMMDNLQEAYTSYQQALYHLRD 152
                 445577889999999999999988854378899999999********************988765 PP

  == domain 2  score: 14.7 bits;  conditional E-value: 2.1e-05
      TPR_21  90 gdlaaAkaqLewvlekakdeelkalarlRLarvllaekkydeAlktLeakkeeafaalvae....lrGDilvaqgkldeAraaYqaAlaaleekarell 184
                 g l++A++++++v+  a+d e ++ +  RL  ++ +++k+++ l+  +   ++  + l +e      G ++ +q+++d A+aaY++ l++  ++a ++l
  EEA22561.1 170 GSLDHAEEAFSQVMRMAPDFEKANEIYFRLGIIYKQQQKFNQSLECFKYIVNDPPRPLTEEdiyfQIGHVHEQQKDFDAAQAAYRRVLDKDPNHA-KVL 267
                 6799*******************************************99999999999888555457***********************99985.333 PP

  == domain 3  score: 6.6 bits;  conditional E-value: 0.0064
      TPR_21 130 deAlktLea.kkeeafaalvaelrGDilvaqgkldeAraaYqaAlaale 177
                 ++A++ Le+ +++++ +a+   l G  +++q k  +A +aYq+A+ + +
  EEA22561.1 285 EKAIEYLEKsVSADNNDAQSWYLLGRCYMSQQKYPKAYEAYQQAVYRDG 333
                 56777775414556677888889999******************97765 PP

>> BTAD  Bacterial transcriptional activator domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.1   1.2e-05      0.01      40     128 ..      64     152 ..      45     154 .. 0.95
   2 !    6.9   0.8    0.0089         8      72     122 ..     278     328 ..     247     331 .. 0.92
   3 ?    6.0   0.1     0.017        15      74     123 ..     348     398 ..     342     410 .. 0.86

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.2e-05
                 TTGGGTTSTTHHHHHHHHHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHSTT-HHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
        BTAD  40 aladleagewleaererleelrlealealaeaelrlGraeealaelealvaehPlrErlhrqlmrAlarsGrqaeALevYerlrrlLae 128
                 +++dl+ g+ +  ++ r ++  + a++a+ +   + ++  +a+++l++ ++++P   +++  l  +   +++ +eA + Y+++  +L++
  EEA22561.1  64 LMGDLDGGMAAYEQALRHNQWSIPAMTAISQIMRTREQFPKAIEYLQQVLKLDPQSGETWGSLGHCHLMMDNLQEAYTSYQQALYHLRD 152
                 5678888999999999******************************************************************9999986 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0089
                 HHHTT-HHHHHHHHHHHHHHSTT-HHHHHHHHHHHHHTT-HHHHHHHHHHH CS
        BTAD  72 elrlGraeealaelealvaehPlrErlhrqlmrAlarsGrqaeALevYerl 122
                  ++++  e+a+++le+ v++++ + +++ +l r+++ + +  +A e+Y+++
  EEA22561.1 278 STSYASQEKAIEYLEKSVSADNNDAQSWYLLGRCYMSQQKYPKAYEAYQQA 328
                 56688899*****************************************97 PP

  == domain 3  score: 6.0 bits;  conditional E-value: 0.017
                 HTT-HHHHHHHHHHHHHHSTT-HHHHHHHHHHHHHTT.-HHHHHHHHHHHH CS
        BTAD  74 rlGraeealaelealvaehPlrErlhrqlmrAlarsG.rqaeALevYerlr 123
                 +++++++al+ ++++++++P+  + +  l + +  ++ ++a+AL +Y r+ 
  EEA22561.1 348 QINQYRDALDAYSRAIRLNPYISEVWYDLGTLYESCNnQTADALDAYGRAA 398
                 578899***************99999999888776651569******9875 PP

>> TPR_MalT  MalT-like TPR region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.9   0.3    0.0081       7.3      66     116 ..      74     122 ..      53     132 .. 0.75
   2 !   13.3   0.1   4.4e-05      0.04      10     113 ..      95     189 ..      93     215 .. 0.78
   3 ?    0.3   0.1      0.41   3.7e+02      42      91 ..     232     282 ..     225     295 .. 0.76
   4 ?    1.4   0.2      0.18   1.7e+02      27     109 ..     287     365 ..     263     371 .. 0.59

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0081
    TPR_MalT  66 aeklarqadslhvallallqqaeilvaqGrLheAletyeqalqlateqglq 116
                 a++ a++++++   ++a++ +++i +++ ++ +A+e  +q l+l +++g++
  EEA22561.1  74 AYEQALRHNQWS--IPAMTAISQIMRTREQFPKAIEYLQQVLKLDPQSGET 122
                 444566777777..7788888888888899999999999999987777654 PP

  == domain 2  score: 13.3 bits;  conditional E-value: 4.4e-05
    TPR_MalT  10 laiasgdaeralelArqALallpeddllariaatavlGeasllqGdleaAlqalqeaeklarqadslhvallallqqaeilvaqGrLheAletyeqalq 108
                 +  +++++++a+e+ +q L+l p++       +  +lG+ +l+  +l++A  ++q+a +++r+ + ++ ++    +++ ++   G+L+ A+e + q ++
  EEA22561.1  95 IMRTREQFPKAIEYLQQVLKLDPQSG-----ETWGSLGHCHLMMDNLQEAYTSYQQALYHLRDPKEPKLWY----GIGILYDRYGSLDHAEEAFSQVMR 184
                 66677788888888888888776654.....5567889999999999999999999999999999999433....346688888999999999999999 PP

    TPR_MalT 109 lateq 113
                 +a++ 
  EEA22561.1 185 MAPDF 189
                 88875 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.41
    TPR_MalT  42 atavlGeasllqGdleaAlqalqeaek.larqadslhvallallqqaeilv 91 
                 +++ +G+++  q d++aA++a++ + +     a+ l++  + + qq+  + 
  EEA22561.1 232 IYFQIGHVHEQQKDFDAAQAAYRRVLDkDPNHAKVLQQLGWLYHQQSTSYA 282
                 567789999999999999999998885155666666777887777776665 PP

  == domain 4  score: 1.4 bits;  conditional E-value: 0.18
    TPR_MalT  27 ALallpeddllar..iaatavlGeasllqGdleaAlqalqeaeklarqadslhvallallqqaeilvaqGrLheAletyeqalql 109
                 A+++l+++       ++  ++lG+ ++ q + ++A +a+q+a++      +++   +  ++++ ++ + ++ ++Al+ y +a++l
  EEA22561.1 287 AIEYLEKSVSADNndAQSWYLLGRCYMSQQKYPKAYEAYQQAVYRD--GRNPT--FW--CSIGVLYYQINQYRDALDAYSRAIRL 365
                 4444444433333224445678888888888888888888877643..33333..22..22333444444455577777777776 PP

>> DUF2225  Uncharacterized protein conserved in bacteria (DUF2225)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.8   0.0    0.0014       1.2     141     194 ..     136     185 ..     128     198 .. 0.85
   2 ?    5.6   2.3     0.013        12     103     193 ..     249     364 ..     204     372 .. 0.65

  Alignments for each domain:
  == domain 1  score: 8.8 bits;  conditional E-value: 0.0014
     DUF2225 141 lkkAlelykeayekesfpvegideatvlYLiaeLerrlgnkeealrwlskvigs 194
                 l++A+  y++a+++ ++p     e ++ Y i+ L  r+g+ ++a +++s+v+++
  EEA22561.1 136 LQEAYTSYQQALYHLRDPK----EPKLWYGIGILYDRYGSLDHAEEAFSQVMRM 185
                 7899999999999999965....558*************************986 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.013
     DUF2225 103 allcyelkkekkskkAklalrlAWlyrdked...............................eekeklflkkAlelykeayekesfpvegideatvlYL 170
                 a   y     k+ + Ak++ +l+Wly ++                                  +++++ + kA+e y++a++ + +      + t    
  EEA22561.1 249 AQAAYRRVLDKDPNHAKVLQQLGWLYHQQSTsyasqekaieyleksvsadnndaqswyllgrCYMSQQKYPKAYEAYQQAVYRDGR------NPTFWCS 341
                 555566666778899************99997777666666666666666654444444444444444444444444444443332......3335555 PP

     DUF2225 171 iaeLerrlgnkeealrwlskvig 193
                 i+ L +++ ++++al ++s+ i+
  EEA22561.1 342 IGVLYYQINQYRDALDAYSRAIR 364
                 67777777777777777777665 PP

>> TPR_20  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0       1.1   9.9e+02       8      54 ..      72     118 ..      69     124 .. 0.88
   2 ?    5.2   0.3      0.03        27       8      61 ..     250     303 ..     242     308 .. 0.84
   3 ?   10.3   0.0   0.00075      0.67       2      49 ..     282     329 ..     281     335 .. 0.88
   4 ?    1.0   0.0      0.59   5.3e+02      11      44 ..     325     358 ..     322     367 .. 0.78

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 1.1
      TPR_20   8 laeleaalaanpddldarldlAlallaagryeeAleqLleilkrdrk 54 
                 +a+ e+al  n   + a+ + ++    +++  +A+e L ++lk d +
  EEA22561.1  72 MAAYEQALRHNQWSIPAMTAISQIMRTREQFPKAIEYLQQVLKLDPQ 118
                 678899999999999999999999****************9998865 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.03
      TPR_20   8 laeleaalaanpddldarldlAlallaagryeeAleqLleilkrdrkweddaar 61 
                  a+ ++ l ++p+  +   +l  ++++++   ++ e+ +e l++  ++++++a+
  EEA22561.1 250 QAAYRRVLDKDPNHAKVLQQLGWLYHQQSTSYASQEKAIEYLEKSVSADNNDAQ 303
                 4667788899*******************9999999999999998888877765 PP

  == domain 3  score: 10.3 bits;  conditional E-value: 0.00075
      TPR_20   2 aadapelaeleaalaanpddldarldlAlallaagryeeAleqLleil 49 
                 a++++ ++ le+ + a+ +d +  + l + ++++++y +A e+  + +
  EEA22561.1 282 ASQEKAIEYLEKSVSADNNDAQSWYLLGRCYMSQQKYPKAYEAYQQAV 329
                 6778899*********************************99766555 PP

  == domain 4  score: 1.0 bits;  conditional E-value: 0.59
      TPR_20  11 leaalaanpddldarldlAlallaagryeeAleq 44 
                  ++a+  +  +    +    ++++ ++y++Al++
  EEA22561.1 325 YQQAVYRDGRNPTFWCSIGVLYYQINQYRDALDA 358
                 567777777777777888999***********97 PP

>> MIT  MIT (microtubule interacting and transport) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0      0.22   1.9e+02      29      40 ..     104     116 ..      99     124 .. 0.76
   2 ?    5.3   0.2     0.023        20      19      34 ..     135     150 ..     133     152 .. 0.89
   3 ?    0.8   0.2       0.6   5.3e+02       2      17 ..     285     300 ..     284     304 .. 0.78
   4 ?    5.8   1.8     0.016        14      17      31 ..     315     329 ..     314     330 .. 0.92
   5 ?    2.8   0.1      0.14   1.2e+02      18      33 ..     350     365 ..     343     367 .. 0.88
   6 ?   -2.4   0.1       5.8   5.2e+03      18      33 ..     385     400 ..     384     400 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.22
         MIT  29 ealelLlqalk.e 40 
                 +a+e+L+q+lk  
  EEA22561.1 104 KAIEYLQQVLKlD 116
                 8*********933 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.023
         MIT  19 nyeeAlelYkealelL 34 
                 n +eA+  Y++al +L
  EEA22561.1 135 NLQEAYTSYQQALYHL 150
                 89**********9887 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.6
         MIT   2 dkAlelvkkAveeDna 17 
                 +kA+e+++k v +Dn+
  EEA22561.1 285 EKAIEYLEKSVSADNN 300
                 5888888888888886 PP

  == domain 4  score: 5.8 bits;  conditional E-value: 0.016
         MIT  17 agnyeeAlelYkeal 31 
                 +++y++A+e+Y++a+
  EEA22561.1 315 QQKYPKAYEAYQQAV 329
                 69***********97 PP

  == domain 5  score: 2.8 bits;  conditional E-value: 0.14
         MIT  18 gnyeeAlelYkealel 33 
                 ++y +Al++Y+ a++l
  EEA22561.1 350 NQYRDALDAYSRAIRL 365
                 79***********975 PP

  == domain 6  score: -2.4 bits;  conditional E-value: 5.8
         MIT  18 gnyeeAlelYkealel 33 
                 ++ ++Al++Y  a +l
  EEA22561.1 385 NQTADALDAYGRAADL 400
                 67789*****999885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (841 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       889  (0.0495845); expected 358.6 (0.02)
Passed bias filter:                      569  (0.0317363); expected 358.6 (0.02)
Passed Vit filter:                        64  (0.00356964); expected 17.9 (0.001)
Passed Fwd filter:                        25  (0.00139439); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              20  [number of targets reported over threshold]
# CPU time: 0.94u 0.30s 00:00:01.24 Elapsed: 00:00:00.60
# Mc/sec: 4258.16
//
Query:       EEA22562.1  [L=464]
Description: hypothetical protein PMAA_091890 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
        8.9    4.4  14.2         12    4.0  14.2    1.1  1  PAT1            Topoisomerase II-associated protein PAT1


Domain annotation for each model (and alignments):
>> PAT1  Topoisomerase II-associated protein PAT1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0  14.2   0.00068        12     210     315 ..     202     312 ..     170     348 .. 0.38

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.00068
        PAT1 210 kkaaqaaaaaaasqqPaaeqaeqaeaaaqaaka........eqaqqapesakeqqqeqeqaaqaqqkkeqgkpvtilqrpqskqakpaepsasseaqe. 299
                 +++a +++ +++++ P++++ +q + ++ + +         ++++++p+  ++ ++++++      +++++++ +++++p++ +++++++s+++ ++e 
  EEA22562.1 202 QRKALTQQPKSQHKDPNEYKMNQVTISSDSDSDasmfasttATTNRHPNPPQS-HSHHHH------HHHHHHHHHQHHHPTTLPTNNNTSSTTNPSSEk 293
                 22222222222223344333333333322222233333221111111111111.111111......122222222222222222222222222221110 PP

        PAT1 300 ...akqqappakvqptqil 315
                    ++++++++ +  + il
  EEA22562.1 294 rktTTHRTHETIHITNTIL 312
                 0001122222222233333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (464 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1305  (0.0727871); expected 358.6 (0.02)
Passed bias filter:                      414  (0.0230911); expected 358.6 (0.02)
Passed Vit filter:                        70  (0.00390429); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.72u 0.30s 00:00:01.02 Elapsed: 00:00:00.49
# Mc/sec: 2821.33
//
Query:       EEA22563.1  [L=223]
Description: glutathione-S-transferase theta, GST, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.5e-09   37.4   0.0    4.5e-09   36.5   0.0    1.4  1  GST_N     Glutathione S-transferase, N-terminal domain
    2.2e-05   24.8   0.0    3.7e-05   24.1   0.0    1.3  1  GST_N_3   Glutathione S-transferase, N-terminal domain
    4.1e-05   23.8   0.0      9e-05   22.7   0.0    1.5  1  GST_N_2   Glutathione S-transferase, N-terminal domain
  ------ inclusion threshold ------
      0.014   15.5   0.0      0.024   14.8   0.0    1.3  1  GST_C_3   Glutathione S-transferase, C-terminal domain
      0.085   12.9   0.0       0.14   12.2   0.0    1.3  1  TetR_C_7  AefR-like transcriptional repressor, C-terminal dom


Domain annotation for each model (and alignments):
>> GST_N  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.5   0.0   1.2e-12   4.5e-09       4      71 ..       6      74 ..       3      77 .. 0.89

  Alignments for each domain:
  == domain 1  score: 36.5 bits;  conditional E-value: 1.2e-12
                EEESSSTSHTHHHHHHHHHHTT-EEEEEEECSTTTCGGCHHHHHHCTTS-SSEEEET.....TEEEESHHHHH CS
       GST_N  4 tlysirgsprahrirlllaakgveyevvpldfeageekspellklnplgkvPaLedn.....gkkltESraIl 71
                + y  +g + ++++++ll +++v++e +++++++++   +e+l lnp+g+vP+ + +     ++++tE+ aIl
  EEA22563.1  6 KFYYSPG-SCSFAVHILLFEANVSFEPIRVEMGKFP---KEFLALNPKGRVPVIILKgdhnnDQVITEAPAIL 74
                5566666.688*********************8887...69*************98888999**********8 PP

>> GST_N_3  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.0     1e-08   3.7e-05      12      67 ..      17      77 ..       7      85 .. 0.81

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 1e-08
                HHHHHHHHHT--EEEE---TTTTHHHHHHH-TT--SSEE....ETT.S-EEESHHHHHHHH CS
     GST_N_3 12 rvrlaLnekglpvevvevtpgehdeellaknplgkvPvL....edd.gealtdSlaIidyL 67
                 v+++L e ++++e   v+ g+ + e+la np+g+vPv+     ++ ++++t+  aI+  +
  EEA22563.1 17 AVHILLFEANVSFEPIRVEMGKFPKEFLALNPKGRVPVIilkgDHNnDQVITEAPAILTTV 77
                58999**********************************7765333477****99998765 PP

>> GST_N_2  Glutathione S-transferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   0.0   2.5e-08     9e-05       7      65 ..      17      75 ..      13      78 .. 0.75

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 2.5e-08
                HHHHHHHHCT--EEEEEEH...-TTSHHHHHHHHCTTTSSSEEE-C.TTE...EEESHHHHHH CS
     GST_N_2  7 RvlialalkglediisvvvlepkgfekseefprlnprgtVPvLwdk.dgq...vineSseIlr 65
                 v+i+l + ++ ++ + v +     + + ef++lnp+g VPv+++k d +   vi+e  +Il 
  EEA22563.1 17 AVHILLFEANVSFEPIRVEM----GKFPKEFLALNPKGRVPVIILKgDHNndqVITEAPAILT 75
                58888888888888767733....345679***************64222455**99999986 PP

>> GST_C_3  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.8   0.0   6.6e-06     0.024      15      89 ..     126     208 ..     108     212 .. 0.67

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 6.6e-06
                 CHHHHHHHHHHHHHHHCHHHHHHHHHH......C.HGTSSSSTTS--HHHHHHHHHHH.HHHHHTCC.CC-HHHHHHHHHHHTS CS
     GST_C_3  15 keeaekkkefleerlpkflkyfekvlk......k.kgggylvgdklTyADlalfqvld.gleeaeal.kkfpklkalyervear 89 
                 ++e e ++ + e+ ++++l+ +e++ +      + +g ++ vg+ +T++D  l  +   g+++++ + +++ k +al++++e++
  EEA22563.1 126 PTE-EDARRIAEKAVETILSCYETIESklyssyTaSGAPFAVGNAMTVVDPYLAVFYRwGVRNLKLDmTRYQKYTALWKELEKL 208
                 333.55555555666666665555544455598448888***********8776655426666644458999999999888765 PP

>> TetR_C_7  AefR-like transcriptional repressor, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   3.9e-05      0.14      83     118 ..     114     147 ..     103     148 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 3.9e-05
                 HHHTHHHHHH------HHHHHHHHHHHHHHHHHHHB CS
    TetR_C_7  83 gelfwprlfgveeppseeeiervvesaVdmFlaaYg 118
                 + ++ p +f+   +p+ee+ +r++e+aV+++l +Y+
  EEA22563.1 114 AGFWRPDRFMN--EPTEEDARRIAEKAVETILSCYE 147
                 55666667776..89********************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (223 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       327  (0.0182386); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.37u 0.24s 00:00:00.61 Elapsed: 00:00:00.37
# Mc/sec: 1826.61
//
Query:       EEA22564.1  [L=194]
Description: hypothetical protein PMAA_091910 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-09   38.6   0.9    4.9e-09   36.6   0.1    2.0  2  HsbA      Hydrophobic surface binding protein A
     0.0044   17.1   0.0      0.019   15.0   0.0    2.1  1  ETRAMP    Malarial early transcribed membrane protein (ETRAMP
  ------ inclusion threshold ------
      0.076   12.7   0.1      0.093   12.4   0.1    1.2  1  DUF1131   Protein of unknown function (DUF1131)
       0.14   12.4   0.3        4.5    7.4   0.0    2.2  2  DUF1380   Protein of unknown function (DUF1380)


Domain annotation for each model (and alignments):
>> HsbA  Hydrophobic surface binding protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.6   0.1   1.1e-12   4.9e-09      17     112 ..      52     143 ..      41     150 .. 0.88
   2 ?   -0.0   0.0      0.25   1.1e+03      37      54 ..     164     181 ..     162     188 .. 0.66

  Alignments for each domain:
  == domain 1  score: 36.6 bits;  conditional E-value: 1.1e-12
                 HHHHHHHH--SH..HHHHHHHHHHHHHHHHHHHHHHHTS----HHHHHHHHHHHHHCHHHHHHHHHHHHHTHHHHHHHT-HHHHHHHHHHHHHHHH CS
        HsbA  17 aldtavnafnGgasalpilsasnalvsaikkattdaqasapltdeealalaqavqtLepdvkaaldaliaKkpafdkagltslvlssLqdlkaasd 112
                 ++++++ +     s + +++++ a+ + i++++  +   ++l+  +  +l + ++++e+ ++ +l+al++Kk ++  +g+++   ++L+dlk+a  
  EEA22564.1  52 QFTNDIEK----QSFQVLHKDVVAILQRIEDGIRRIALESQLDSRDVYSLEDGFKAFEKNIEEVLKALKDKKTDIVGSGVCAELVKDLKDLKDAGR 143
                 44444444....56889***************************************************************************9865 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 0.25
                 HHHHHHHHHHHHHHHHHT CS
        HsbA  37 asnalvsaikkattdaqa 54 
                 asn+  + i+++++d ++
  EEA22564.1 164 ASNKALQEIQDTINDFSK 181
                 666666666666666554 PP

>> ETRAMP  Malarial early transcribed membrane protein (ETRAMP)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   4.3e-06     0.019       1      46 [.       1     176 [.       1     184 [. 0.77

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 4.3e-06
      ETRAMP   1 MKvtkv.llffafLlavnlltpeslcdevnkkk.................................................................. 32 
                 MK+ +  l+++++ l+   l++++++++v+k                                                                    
  EEA22564.1   1 MKFLQFlLSLIILSLSARALASSCNNYHVTKALgdrrvfanvtckvieallqftndiekqsfqvlhkdvvailqriedgirrialesqldsrdvysled 99 
                 9*****8888888899**************877**********99999999999999999999999999999999999999999999999999999988 PP

      ETRAMP  33 ...............................................................ekakkaikkiddki 46 
                                                                                + ++ka+++i+d+i
  EEA22564.1 100 gfkafeknieevlkalkdkktdivgsgvcaelvkdlkdlkdagrqisilvvgkmpeeffdigkKASNKALQEIQDTI 176
                 88777777766666666666666666666666666666666666666666666666666666555555555555555 PP

>> DUF1131  Protein of unknown function (DUF1131)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   2.1e-05     0.093      33     120 ..      80     172 ..      55     194 .] 0.67

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2.1e-05
     DUF1131  33 lteeaieealdgd..yrlrsGmetenGkivsifqalkddkvklvisGqekgkveridvldk...eiktewgvkiGtpfsdlyskafgaCkkgs 120
                 ++  a+e++ld++  y l +G ++ + +i ++++alkd+k+ +v sG     v+ ++ l +   +i+     k+ ++f d+ +ka ++  +  
  EEA22564.1  80 IRRIALESQLDSRdvYSLEDGFKAFEKNIEEVLKALKDKKTDIVGSGVCAELVKDLKDLKDagrQISILVVGKMPEEFFDIGKKASNKALQEI 172
                 566788888885444********************************9999998886554401145555555666677777777665443332 PP

>> DUF1380  Protein of unknown function (DUF1380)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.0    0.0031        14      40      82 ..      61     103 ..      43     109 .. 0.82
   2 ?    7.4   0.0     0.001       4.5      31      89 ..      93     147 ..      90     178 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0031
     DUF1380  40 eyslseqevravlarlddipeeqrlesGissaavmelieqvke 82 
                  + + +++v a+l+r++d      les + s+ v  l ++ k 
  EEA22564.1  61 SFQVLHKDVVAILQRIEDGIRRIALESQLDSRDVYSLEDGFKA 103
                 4567889***********9999999999999999998887775 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.001
     DUF1380  31 diealadgmeyslseqevravlarlddipeeqrlesGissaavmelieqvkenrktvtv 89 
                 d+ +l dg      e++++ vl +l+d    + + sG+ +++v++l +++k++++++ +
  EEA22564.1  93 DVYSLEDGF--KAFEKNIEEVLKALKDKK-TDIVGSGVCAELVKDL-KDLKDAGRQISI 147
                 777777777..556899********9975.5679***********7.678998888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (194 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1223  (0.0682135); expected 358.6 (0.02)
Passed bias filter:                      811  (0.045234); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 1334.49
//
Query:       EEA22565.1  [L=506]
Description: hypothetical protein PMAA_091920 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
     0.0096   15.8   0.1        3.5    7.6   0.0    2.5  2  Gemini_C4  Geminivirus C4 protein


Domain annotation for each model (and alignments):
>> Gemini_C4  Geminivirus C4 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.5   0.0   0.00086        15      14      64 ..     127     180 ..     123     197 .. 0.73
   2 !    7.6   0.0    0.0002       3.5      13      29 ..     312     328 ..     302     337 .. 0.76

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.00086
   Gemini_C4  14 enssakikdsstWyPqPGqhisirtfrelnpa..P.tskptstrtetqsnGens 64 
                 ++s+a+ +d +   Pq G  i  +  re +++  P  +  t  ++e+++  ++ 
  EEA22565.1 127 VESEAQKDDKAGIKPQEGEKIETKLIREDDKItpPqEAATTPQQVESKAQKDDE 180
                 6899***********************988762121233344566776666655 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0002
   Gemini_C4  13 kenssakikdsstWyPq 29 
                  e  s ++ d+stWyP 
  EEA22565.1 312 TETKSIQLMDMSTWYPM 328
                 45667899********6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (506 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1013  (0.0565006); expected 358.6 (0.02)
Passed bias filter:                      557  (0.031067); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.30s 00:00:00.98 Elapsed: 00:00:00.50
# Mc/sec: 3059.78
//
Query:       EEA22566.1  [L=178]
Description: hypothetical protein PMAA_091930 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (178 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       455  (0.0253779); expected 358.6 (0.02)
Passed bias filter:                      375  (0.0209158); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.40
# Mc/sec: 1322.22
//
Query:       EEA22567.1  [L=357]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (357 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       621  (0.0346366); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2484.80
//
Query:       EEA22568.1  [L=1273]
Description: pre-rRNA processing protein Rrp12, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-79  266.6   0.1      2e-77  259.4   0.1    3.5  3  NUC173    NUC173 domain
    0.00049   20.1   1.4        3.7    8.0   0.1    4.2  3  HEAT      HEAT repeat
  ------ inclusion threshold ------
      0.011   16.1   1.2       0.53   10.7   0.1    3.9  4  HEAT_2    HEAT repeats


Domain annotation for each model (and alignments):
>> NUC173  NUC173 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0     0.067     4e+02      17      56 ..     265     305 ..     250     312 .. 0.81
   2 !  259.4   0.1   3.4e-81     2e-77       2     204 .]     388     589 ..     387     589 .. 0.98
   3 ?    1.5   0.0     0.032   1.9e+02       2      75 ..     917     991 ..     874     996 .. 0.85

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.067
      NUC173  17 awkevlevlsalfeklgkrs.spllkkilktlgelreseef 56 
                  ++  +ev++++fe + +++ s  l ++l+ ++elr ++++
  EEA22568.1 265 ITMGAFEVFEVIFEGMADEFsSSKLPRLLEAIQELRPAQND 305
                 5667899*********99996667***********998865 PP

  == domain 2  score: 259.4 bits;  conditional E-value: 3.4e-81
      NUC173   2 llkaleslLslkyqaawkevlevlsalfeklgkrsspllkkilktlgelreseefelkkeadevigaairamGpevvLevlPLnleeeeeeklsegraW 100
                 l+k  ++lLs+kyqaaw ev++v++a+fe++++rs+p+l +i++t+gelr++++f+ kkeadev+g a+ amGp  +L++lPLn+ e  ++++++gr+W
  EEA22568.1 388 LAKFASELLSVKYQAAWVEVFNVCAAMFEAFKWRSTPYLVNIVRTIGELRSNDSFQGKKEADEVLGRAVYAMGPAEILRILPLNIIE--QKAGQPGRVW 484
                 778899********************************************************************************6..5569****** PP

      NUC173 101 LLPlLrdnvrnaeLafFveellplaealeqkakeaeeakksveakiletlveqiWslLPsfcelptDlkesf.kklaklLsnaLyeqpeLrltickaLr 198
                 LLP+Lrdn +n++La+F++e++pl+eal+q++ e+ +a+k+ve+ki+et+++qiWs+LP++celp Dl++ f + +a+lLsn+Ly+q+eLr++ic+aL+
  EEA22568.1 485 LLPILRDNASNTHLAHFRSEMVPLSEALYQRVLEFGQAEKTVEVKIFETIIQQIWSILPGYCELPLDLETGFdQGFAELLSNVLYKQTELRVDICRALQ 583
                 *************************************************************************************************** PP

      NUC173 199 kLvesn 204
                 +Lvesn
  EEA22568.1 584 NLVESN 589
                 ****98 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.032
      NUC173   2 llkaleslLslkyqaawkevlevlsalfeklgkrs.spllkkilktlgelreseefelkkeadevigaairamGp 75 
                 l++++e +L+ + ++ ++ vl + ++++  l + + +p l++++ +l  + ++++  l+++++ ++   +r  G+
  EEA22568.1 917 LVETVELFLTSNNREIVRSVLGFAKVAVVCLPEDMlRPRLNSLVPNLMVWSKEHKGRLRTKVKGILDRLVRRFGA 991
                 577888888888889999999999999999988877888999999999999999888899888888888888875 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.3   0.0    0.0049        29       5      28 ..     148     171 ..     146     173 .. 0.87
   2 !    8.0   0.1   0.00063       3.7       1      31 []     338     368 ..     338     368 .. 0.89
   3 ?    3.0   0.0     0.027   1.6e+02       1      29 [.     811     839 ..     811     841 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0049
                 HHHHHT-SSHHHHHHHHHHHHHHH CS
        HEAT   5 llkllsDpspeVReaAakaLgala 28 
                 ll+l  D  p+VR+ A  aL++++
  EEA22568.1 148 LLNLAVDHRPKVRKRAQDALVKVL 171
                 688889**************9876 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.00063
                 HHHHHHHHHT-SSHHHHHHHHHHHHHHHHCS CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgalaevl 31 
                 l+ l+ + ls+ps ++R +A ++L  ++ ++
  EEA22568.1 338 LFELIASFLSSPSKNIRISASECLISFLANC 368
                 56789999****************9998776 PP

  == domain 3  score: 3.0 bits;  conditional E-value: 0.027
                 HHHHHHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgalae 29 
                 +lP ++  ++ ++ + R aA+  L +la+
  EEA22568.1 811 ILPEVILGCKESNDKARTAAFDLLIHLAK 839
                 78998888999**************9998 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.1   8.9e-05      0.53      26      61 ..     138     174 ..     127     202 .. 0.79
   2 ?    0.6   0.0      0.13   7.8e+02      32      56 ..     338     362 ..     324     393 .. 0.77
   3 ?   -1.9   0.0      0.75   4.5e+03      14      55 ..     786     834 ..     772     846 .. 0.65
   4 ?   -3.9   0.0         3   1.8e+04      43      58 ..     886     901 ..     881     919 .. 0.69

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 8.9e-05
      HEAT_2  26 rignpealpaLvellededpavRraaaeaLgai.gdp 61 
                 +ig+++a + L++l+ d+ p vR+ a +aL+++ ++p
  EEA22568.1 138 QIGPRRATAGLLNLAVDHRPKVRKRAQDALVKVlKTP 174
                 8999**************************9975444 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.13
      HEAT_2  32 alpaLvellededpavRraaaeaLg 56 
                 +++++ ++l++++ ++R  a e L 
  EEA22568.1 338 LFELIASFLSSPSKNIRISASECLI 362
                 5677778888888888888888774 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 0.75
      HEAT_2  14 pevrraairaLgrignp.......ealpaLvellededpavRraaaeaL 55 
                    r  ai++L ++ ++       ++lp ++  ++ ++   R aa + L
  EEA22568.1 786 RRDRLLAIHELVTYLPTsdlhfipSILPEVILGCKESNDKARTAAFDLL 834
                 3477888888885443334444447788888888888888888887665 PP

  == domain 4  score: -3.9 bits;  conditional E-value: 3
      HEAT_2  43 edpavRraaaeaLgai 58 
                 ++p+  +a ++aL+++
  EEA22568.1 886 TSPHMVAASVTALSRL 901
                 6889999999999865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1273 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       755  (0.0421105); expected 358.6 (0.02)
Passed bias filter:                      573  (0.0319594); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.93u 0.28s 00:00:01.21 Elapsed: 00:00:00.46
# Mc/sec: 8241.12
//
Query:       EEA22569.1  [L=169]
Description: small nuclear ribonucleoprotein (LSM1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-16   59.9   0.1    1.4e-16   59.9   0.1    1.6  2  LSM       LSM domain
  ------ inclusion threshold ------
      0.041   14.3   0.1      0.062   13.8   0.1    1.3  1  RecX      RecX family
       0.25   11.5   3.4        0.4   10.8   3.4    1.3  1  DUF4710   Domain of unknown function (DUF4710)
        0.9    8.7   3.8         17    4.5   2.2    2.0  2  SMN       Survival motor neuron protein (SMN)


Domain annotation for each model (and alignments):
>> LSM  LSM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.9   0.1   3.1e-20   1.4e-16       3      66 ..      45     110 ..      43     111 .. 0.96
   2 ?   -2.1   0.1      0.72   3.2e+03      45      51 ..     144     150 ..     129     156 .. 0.49

  Alignments for each domain:
  == domain 1  score: 59.9 bits;  conditional E-value: 3.1e-20
                 HHHTTTSEEEEEETTSEEEEEEEEEEETTSEEEEEEEEEEETTET..EEEEEEEEEEEGGGEEEEE CS
         LSM   3 lkklinkkvtvelkngrelrGtLkgfDqfmNlvLedveetlkdkk..ekrklglvliRGnnivlis 66 
                 l +l++kk+++ l++gr+l+G+L++ Dqf NlvL+d++e++  ++   ++++gl+l+RG+n++l++
  EEA22569.1  45 LLDLTDKKLVLVLRDGRKLIGVLRSWDQFANLVLQDTVERIYAGNlyAEEHVGLYLVRGENVLLLG 110
                 77899**********************************************************986 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.72
                 TETEEEE CS
         LSM  45 dkkekrk 51 
                 +kk k++
  EEA22569.1 144 KKKDKKS 150
                 2213333 PP

>> RecX  RecX family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.1   1.4e-05     0.062      68     116 ..     122     168 ..     109     169 .] 0.70

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.4e-05
                 TS-HHHHHHHHHHHHHHHTTTS-HHHHHHHHHHHHHHTT--HHHHHHHH CS
        RecX  68 eldeeeqarelaekklkklkkeedekekqklvrfLarrGFssevirevl 116
                 e+  ++ ++e+ e k+k+   ee++k+ +k v +L+++GF+ e   evl
  EEA22569.1 122 ETLTQTSMKEVRELKAKEE--EERKKKDKKSVGKLQTHGFEPEHSGEVL 168
                 3333444555555555555..56799999*************9988776 PP

>> DUF4710  Domain of unknown function (DUF4710)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   3.4     9e-05       0.4      19      52 ..     124     156 ..     114     160 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 9e-05
     DUF4710  19 LeededqkeakeekkkkkkqklKKyrKnvgKalr 52 
                 L +  + ke++e k k   +++KK +K vgK  +
  EEA22569.1 124 LTQ-TSMKEVRELKAKEEEERKKKDKKSVGKLQT 156
                 444.488999999******************765 PP

>> SMN  Survival motor neuron protein (SMN)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   2.2    0.0038        17     192     214 ..      15      37 ..       5      45 .. 0.79
   2 ?    3.9   0.0    0.0061        27      82     142 ..      87     147 ..      76     163 .. 0.74

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.0038
         SMN 192 tlgpflsgwppplpagpplippp 214
                 + g    + ppp+p+gpp +pp 
  EEA22569.1  15 QQGQNQQAGPPPVPQGPPQLPPQ 37 
                 555566778***********995 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.0061
         SMN  82 dgnvypatiasidakkgtcvvvytgygneeeqnladllteasdededalkeanvnetesst 142
                  gn+y+     + + +g  v++  +   ++e++l + lt++s ++   lk ++++e ++  
  EEA22569.1  87 AGNLYAEEHVGLYLVRGENVLLLGEIDLDKEDDLPETLTQTSMKEVRELKAKEEEERKKKD 147
                 4999999999999999999999999999999999999988776544444544444444333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (169 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1048  (0.0584528); expected 358.6 (0.02)
Passed bias filter:                      530  (0.029561); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.41u 0.26s 00:00:00.67 Elapsed: 00:00:00.40
# Mc/sec: 1272.99
//
Query:       EEA22570.1  [L=263]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (263 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       672  (0.0374812); expected 358.6 (0.02)
Passed bias filter:                      456  (0.0254337); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1772.04
//
Query:       EEA22571.1  [L=362]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (362 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       773  (0.0431145); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2545.56
//
Query:       EEA22572.1  [L=433]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.8e-07   27.9   0.1      9e-05   21.5   0.1    2.8  2  Glyco_transf_54  N-Acetylglucosaminyltransferase-IV (GnT-IV) 


Domain annotation for each model (and alignments):
>> Glyco_transf_54  N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.1     5e-09     9e-05      45     199 ..      96     243 ..      56     247 .. 0.73
   2 ?   -0.7   0.0     0.028     5e+02     254     279 ..     369     394 ..     348     401 .. 0.76

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 5e-09
  Glyco_transf_54  45 vslvlGiptvkrekksylldTlesllselseeekkdlvvvvfiaetdeeyvksvveeikkkfkkevesgllevisppasyYpnlsklkktlnDs 138
                       ++ l   tvkr++ +y    + slls l+++e++ + v v+ a+t+++ + s  +    +        ll+ +s  +      ++  ++l+  
       EEA22572.1  96 PRMCLAFVTVKRDHVNYFDASVGSLLSGLNDRERRVFSVNVLFANTNPDVHPSWGQLWMDR--------LLDSVSSYNV----PETDFQSLQAL 177
                      35888999***************************************99776655444444........4444433332....23333444444 PP

  Glyco_transf_54 139 kervkwrtkqnldyafLmlyaqskgeyylql.eDdvvakkgfltkikkfvlakks....keWlvle 199
                      +e  +w+ k   dy++ +  +   g+ y+ + eDd++ + g+l k  ++++  ++    ++Wl+l 
       EEA22572.1 178 EESHNWHEKGIYDYTYALDQCYLTGAPYIGIfEDDIIFADGWLVKTLRALHDIENklkaQNWLYLR 243
                      55678**************9999999999655********99877666555555545559**9985 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.028
  Glyco_transf_54 254 krekeklrirfkpSlFqhvgtqSsle 279
                      +++++ +r  + p + qhvg++Ss +
       EEA22572.1 369 ADKEALRRFALAPPQVQHVGIRSSRD 394
                      55556667778999*********965 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (433 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       397  (0.0221429); expected 358.6 (0.02)
Passed bias filter:                      334  (0.018629); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.41
# Mc/sec: 3171.00
//
Query:       EEA22573.1  [L=363]
Description: integral membrane protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (363 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       687  (0.0383178); expected 358.6 (0.02)
Passed bias filter:                      306  (0.0170673); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.40
# Mc/sec: 2706.99
//
Query:       EEA22574.1  [L=1431]
Description: RNA helicase/RNAse III, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.5e-42  144.5   0.0    2.7e-22   79.4   0.0    3.1  3  Ribonuclease_3   Ribonuclease III domain
    1.5e-24   86.6   0.2      3e-11   43.6   0.0    4.0  3  Ribonucleas_3_3  Ribonuclease-III-like
    2.4e-22   79.5   0.0    6.3e-22   78.2   0.0    1.7  1  DEAD             DEAD/DEAH box helicase
    1.1e-19   70.4   0.1    2.4e-19   69.3   0.1    1.6  1  Dicer_dimer      Dicer dimerisation domain
    6.2e-19   68.4   0.1    1.5e-18   67.2   0.1    1.7  1  Helicase_C       Helicase conserved C-terminal domain
      6e-14   52.4   0.0    1.3e-13   51.3   0.0    1.6  1  ResIII           Type III restriction enzyme, res subunit
  ------ inclusion threshold ------
      0.021   14.3   0.0      0.049   13.1   0.0    1.6  1  PhoH             PhoH-like protein
      0.086   12.4   0.1       0.23   11.0   0.1    1.7  1  Corona_NS1       Coronavirus nonstructural protein NS1


Domain annotation for each model (and alignments):
>> Ribonuclease_3  Ribonuclease III domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       6.2   1.4e+04      84      97 ..     327     385 ..     255     389 .. 0.53
   2 !   79.4   0.0   1.2e-25   2.7e-22       1     105 []     980    1085 ..     980    1085 .. 0.94
   3 !   61.7   0.0   3.8e-20   8.5e-17       1     104 [.    1162    1309 ..    1162    1310 .. 0.71

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 6.2
                     C.............................................TSHHHHHHHHHHH CS
  Ribonuclease_3  84 d.............................................adkvladvvEAli 97 
                     +                                             ++  +++ vEAli
      EEA22574.1 327 AekfieasvkrsdnnifrqwedaekiymmrflsmlpaiaenrvwgsSPDQISQKVEALI 385
                     03333333333334444444454455555555555555555555556667777777776 PP

  == domain 2  score: 79.4 bits;  conditional E-value: 1.2e-25
                      HHHHHHHHHHHHHHHHHHHHHHCTTSSHHHHHHHHHHHTSHHHHHHHHHCTTCHCCHCHH...............HHCCSTTCHCTSHHHHHH CS
  Ribonuclease_3    1 erLeflGDavlklaittylfetypdahegrlsklrsklvsnenlarlakklglpkflrasefdpprnwlppgy.klsddekedddadkvladv 92  
                      +r+eflGD+ lkl+++ +l+   p +heg ls+++  +vsn  l+r a +lgl++f+ +++f+ +++    ++   + +e++++ ++k+ladv
      EEA22574.1  980 QRYEFLGDSLLKLITSIHLVVNNPLWHEGMLSAAKDTIVSNGRLYRTALNLGLDRFILTKSFTGRKWRPSYVSqFETVGEEKRELSTKTLADV 1072
                      79*************************************************************9999988877766778888899******** PP

                      HHHHHHHHHHHCT CS
  Ribonuclease_3   93 vEAliGaiyldsg 105 
                      vE+l+Ga +ld+g
      EEA22574.1 1073 VESLLGAAFLDGG 1085
                      **********987 PP

  == domain 3  score: 61.7 bits;  conditional E-value: 3.8e-20
                      HHHHHHHHHHHHHHHHHHHHHHCT.TSSHHHHHHHHHHHTSHHHHHHHHHCTTCHCCHCHH................................ CS
  Ribonuclease_3    1 erLeflGDavlklaittylfetyp.dahegrlsklrsklvsnenlarlakklglpkflrasefdpprnwlppgy................... 73  
                      +rLeflGD+ l++++++ +f+ +p ++++++++ +r+++v++++l +l+++l    ++++++ +p++ ++  ++                   
      EEA22574.1 1162 QRLEFLGDSLLDHFVVQEFFN-HPeKLSHQEMHLMRTAVVNAHFLGFLCQSL----YITEQRTEPVSPGKAHLStistdhklylwqlmrhgas 1249
                      7********************.884668*********************655....5555555555555555444444444444444444444 PP

                      .....HHCCSTTCHC..................................TSHHHHHHHHHHHHHHHHHC CS
  Ribonuclease_3   74 ....klsddekeddd..................................adkvladvvEAliGaiylds 104 
                          +         +                                  a+k+++d+vE+++Gai++ds
      EEA22574.1 1250 wevmN---------AqqetktryeawgsavhdalnhsktypwaalfrinASKFFSDMVESILGAIFVDS 1309
                      43221.........02222224445556677777777799999999999******************97 PP

>> Ribonucleas_3_3  Ribonuclease-III-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.6   0.0   1.3e-14     3e-11      14     119 ..     970    1092 ..     960    1099 .. 0.78
   2 !   32.2   0.0   4.4e-11   9.8e-08       3      70 ..    1143    1210 ..    1141    1236 .. 0.87
   3 !    5.8   0.0    0.0066        15      94     111 ..    1292    1309 ..    1286    1324 .. 0.70

  Alignments for each domain:
  == domain 1  score: 43.6 bits;  conditional E-value: 1.3e-14
  Ribonucleas_3_3   14 fangr.kghNerLefLGdavLklsvseyllekaek.degeltklraslvseeslaeiAkelgLgkvlrl..............rkgeeeteg 89  
                        ++++ ++ ++r efLGd++Lkl++s +l+ +    +eg l+  ++ +vs+ +l + A +lgL+++++               + +++ +e+
       EEA22574.1  970 ASSAHeENDYQRYEFLGDSLLKLITSIHLVVNNPLwHEGMLSAAKDTIVSNGRLYRTALNLGLDRFILTksftgrkwrpsyvsQFETVGEEK 1061
                       4333304679*************9888776555555*******************************9999999999988875222333333 PP

  Ribonucleas_3_3   90 sg.rekvladaleAliGAiyldkgaevaqef 119 
                       ++  +k lad++e+l+GA +ld+g+e+ ++ 
       EEA22574.1 1062 RElSTKTLADVVESLLGAAFLDGGYEKLEAC 1092
                       330345*******************998765 PP

  == domain 2  score: 32.2 bits;  conditional E-value: 4.4e-11
  Ribonucleas_3_3    3 elleqaltHkSfangrkghNerLefLGdavLklsvseyllekaek.degeltklraslvseeslaeiAk 70  
                       ++l +altH S +n+  ++++rLefLGd++L+  v+++ ++++ek +++e+  +r+++v+ + l  + +
       EEA22574.1 1143 SILFEALTHPS-SNDGAPTYQRLEFLGDSLLDHFVVQEFFNHPEKlSHQEMHLMRTAVVNAHFLGFLCQ 1210
                       68899******.66778999**********************999788899999999**9998876665 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.0066
  Ribonucleas_3_3   94 kvladaleAliGAiyldk 111 
                       k  +d++e+++GAi++d+
       EEA22574.1 1292 KFFSDMVESILGAIFVDS 1309
                       5679***********995 PP

>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.2   0.0   2.8e-25   6.3e-22       2     171 ..      29     197 ..      28     202 .. 0.84

  Alignments for each domain:
  == domain 1  score: 78.2 bits;  conditional E-value: 2.8e-25
                 HHHHHHHHHHHTTCEEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEET...TSSHHHHHHHHHTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxx RF
        DEAD   2 diQaeaiplilgggdvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkkyidlrvlliig...gvaardqlskldng 97 
                 ++Q+e++ + l  ++ +va+eTGsGKT ++++ + +++++   ++++ + +++Pt +Laeq++  ++k +  ++ r+ll        ++++ ++++  +
  EEA22574.1  29 AYQQEMLAESL-RQNTIVAMETGSGKTQIAVLRIQEELSR--CSPEKLVWFLTPTVALAEQQYAVISKQIPLYQSRLLLGSDnvdHWSTQHIWDEILLN 124
                 68999999999.67************************76..99999999****************999998777777654422234455556666678 PP

                 CSEEEEEHHHHHHHHHCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBS.H CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.x RF
        DEAD  98 vdivvgtpgrlddllstgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlp.k 171
                 ++ivv+tp+ l+d +s g ++ls +++lV+DEa+r  + +  + i r+ ++ ++  +d+     ++ l+AT+  k
  EEA22574.1 125 IRIVVSTPQVLLDAMSHGFVKLSGLSLLVFDEAHRCVKANPFNGIMRLYHHARKSGADELPA--ILGLTATPAtK 197
                 ***************************************77777777777777777776655..*******9844 PP

>> Dicer_dimer  Dicer dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.3   0.1   1.1e-22   2.4e-19       3      91 ..     576     667 ..     574     668 .. 0.91

  Alignments for each domain:
  == domain 1  score: 69.3 bits;  conditional E-value: 1.1e-22
  Dicer_dimer   3 slLnrycatlpsdeytdlrpeyevkevedk.ergkfqaevtLPsnsp..lrkieg.epmstkklAkrsaAfeackeLhkaglLddhLlPlske 91 
                    L+++cat +s +yt+++pey+++++e   +  +++a+v+LPs ++  lr + + ++++t+k+Akr+aAf+a+++L++ag++dd+L Pl+++
   EEA22574.1 576 PFLAHFCATGSS-AYTSNQPEYIIDRQEFApGLAQIAAKVVLPSYIDpsLRVAFSkSKWQTEKAAKRDAAFQAYVALYRAGMVDDNLTPLHRR 667
                  679******976.589***********8545999************9988999888*********************************9987 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.2   0.1   6.5e-22   1.5e-18       2     107 ..     380     503 ..     379     506 .. 0.76

  Alignments for each domain:
  == domain 1  score: 67.2 bits;  conditional E-value: 6.5e-22
                 HHHHHHHHH.HHTTTTSEEEEEESSHHHH.........HH......HHHHHHHT...TSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSST CS
  Helicase_C   2 kleallell.kleeeggkilifvntidrl.........ek......vklllekk...gikvavlhgelpqnereeileqfnkgesdvLiatdvaerGid 81 
                 k+eal+  + ++ + g+++++fv+++ ++         +       +k++l ++   + k+a+     + ++++++l++ + g++++Liat+v+e+Gid
  EEA22574.1 380 KVEALITTIaSKYNPGDRVIVFVEQRATVimlahllsvHPltkeivTKYFLGNSnyaNRKSAITEL-STLSDQRDVLAELRVGKTNILIATNVLEEGID 477
                 67777777778899*************552333333331143345666665544565566655555.566677799999******************** PP

                 STTESEEEESSSSSSHHHHHHHHTTS CS
  Helicase_C  82 ipkvnlVinfdlprnvtsyiqriGRt 107
                 +p +n+Vi fd+p++++s+iqr+GR+
  EEA22574.1 478 VPACNMVICFDPPKDLRSFIQRRGRA 503
                 *************************8 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.3   0.0   5.9e-17   1.3e-13       2     170 ..      25     195 ..      24     196 .. 0.80

  Alignments for each domain:
  == domain 1  score: 51.3 bits;  conditional E-value: 5.9e-17
                 -EE-HHHHHHHHHHT......TTSEEEEEESTTSTHHHHH.HHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG..........GEEEESSS- CS
      ResIII   2 lelreyQeeaienlleklkskrdkrglikmaTGtGKTlva.aklierllkkgkeekflflvprkslleqtleefkkflseayke......igkkvsgdk 93 
                 +++r yQ+e++ + l       +++ +++m+TG+GKT +a +++ e+l++  +e+ + fl p+ +l eq +  ++k ++ ++++      +   +s ++
  EEA22574.1  25 IKPRAYQQEMLAESL-------RQNTIVAMETGSGKTQIAvLRIQEELSRCSPEKLVWFLTPTVALAEQQYAVISKQIPLYQSRlllgsdNVDHWSTQH 116
                 688999999998887.......5789**************99999**********************************99866776554333344444 PP

                 B--.......-SEEEEEHHHHHHTH........HHHTTT-SEEEEETGGGTTS.TTTHHHHHT---.........SEEEEEESS-S CS
      ResIII  94 kkakekdstnkkilvttiqsldadseeeeeeseellrdrfdviiiDEaHrlgakkswreilekfke.........avllglTATpe 170
                      +   n++i+v+t q l  ++      +   + +   ++++DEaHr  +++ ++ i++ + +           +lglTATp 
  EEA22574.1 117 IW--DEILLNIRIVVSTPQVLLDAM-----SHGFVKLSGLSLLVFDEAHRCVKANPFNGIMRLYHHarksgadelPAILGLTATPA 195
                 33..3677899**********9999.....33444444555************98777775555444556777889********96 PP

>> PhoH  PhoH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   2.2e-05     0.049       2      53 ..      25      74 ..      24      90 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2.2e-05
                ----SHHHHHHHHHHHH-SEEEEE--TTSSTTHHHHHHHHHHHHTTS-SEEE CS
        PhoH  2 ikpktkeQkeylealkkndivfaiGpaGtGKtylavalavealkkkkvkrii 53
                ikp+  +Q+ ++e+l++n+iv +  ++G+GKt +av    e l++ + ++++
  EEA22574.1 25 IKPRAYQQEMLAESLRQNTIVAM--ETGSGKTQIAVLRIQEELSRCSPEKLV 74
                99****************99987..79*********9888888877777776 PP

>> Corona_NS1  Coronavirus nonstructural protein NS1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.1    0.0001      0.23      14      23 ..    1338    1347 ..    1337    1349 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.0001
  Corona_NS1   14 DILHPsNHVk 23  
                  D LHP+NHV+
  EEA22574.1 1338 DCLHPFNHVR 1347
                  89*******6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1431 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       473  (0.0263818); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.81u 0.28s 00:00:01.09 Elapsed: 00:00:00.45
# Mc/sec: 9563.82
//
Query:       EEA22575.1  [L=275]
Description: proteasome component Pre8, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.4e-57  192.4   0.1    1.1e-32  113.1   0.0    2.2  2  Proteasome      Proteasome subunit
    8.9e-11   41.3   0.1    3.1e-10   39.5   0.0    1.9  2  Proteasome_A_N  Proteasome subunit A N-terminal signature


Domain annotation for each model (and alignments):
>> Proteasome  Proteasome subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  113.1   0.0   1.2e-36   1.1e-32       1     123 [.      28     149 ..      28     159 .. 0.94
   2 !   77.4   0.0   1.1e-25   9.7e-22     114     190 .]     166     239 ..     161     239 .. 0.94

  Alignments for each domain:
  == domain 1  score: 113.1 bits;  conditional E-value: 1.2e-36
                 HHHS-EEEEEEETTEEEEEEEEEEEETTEEEESSSSTSEEEEETTEEEEEEESHHHHHHHHHHHHHHHH.HHHHHHSSGTCHHHHHHHHHHHHHHHHHH CS
  Proteasome   1 vkkGttvvGikgkdgvvlaadkratagskllskstveKifkiddhigvafaGlaaDartlvrraraeaq.lyrlrygrpipverlvarvaaklqaytqr 98 
                 v++G t++Gik+++gvvla++k+++  s+l++  +++Ki+ +++ ig+++aG+ +D+r+lv++ar+  +  y+  y++ +p+++lv+ va+ +q+ tq+
  EEA22575.1  28 VNQGVTALGIKATNGVVLATEKKSS--STLIEAPSLSKISLVTPDIGMVYAGMGPDYRVLVDKARKVSHtGYKRIYNEYPPTRILVQDVARIVQEATQS 124
                 789**********************..**************************************9777258899************************ PP

                 CTTTTTSEEEEEEEEETTTEEEEEE CS
  Proteasome  99 sgrrpfgvslliagvdeeggpeLyq 123
                 +g+rp+gvslliag+de  +pe+ +
  EEA22575.1 125 GGVRPYGVSLLIAGWDEGVEPEVAE 149
                 ****************999999876 PP

  == domain 2  score: 77.4 bits;  conditional E-value: 1.1e-25
                 ETTTEEEEEEEETTSEEEEESSEEEESTTHHHHHHHHHHHHSTTBSHHHHHHHHHHHHHHHHHHBTTSCSSEEEEEE CS
  Proteasome 114 deeggpeLyqidpsGsyieekdavaiGsgseaaktalekeykedltleeavelavkalkealerdklsgknievavi 190
                   +ggp+Lyq+dpsGsy+ +k a+aiG+ +++akt+lek+y+e l+le+a+++a+ +lke++e++ ++g+++e++++
  EEA22575.1 166 L-KGGPSLYQVDPSGSYFPWK-ATAIGKSATSAKTFLEKRYTEGLELEDAIHIALLTLKETIEGE-MNGDTVEIGIV 239
                 4.789***************8.*****99**********************************77.********997 PP

>> Proteasome_A_N  Proteasome subunit A N-terminal signature
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.5   0.0   3.4e-14   3.1e-10       1      23 []       5      27 ..       5      27 .. 0.98
   2 ?   -1.3   0.0       0.2   1.8e+03      14      18 ..     172     176 ..     171     176 .. 0.88

  Alignments for each domain:
  == domain 1  score: 39.5 bits;  conditional E-value: 3.4e-14
  Proteasome_A_N  1 YDrslttFSPdGRLfQVEYAmkA 23
                    Y +slttFSP+G+L Q+EYA++A
      EEA22575.1  5 YSFSLTTFSPSGKLVQIEYALNA 27
                    99*******************98 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.2
  Proteasome_A_N  14 LfQVE 18 
                     L+QV+
      EEA22575.1 172 LYQVD 176
                     9***7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       294  (0.016398); expected 358.6 (0.02)
Passed bias filter:                      268  (0.0149478); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.21s 00:00:00.63 Elapsed: 00:00:00.38
# Mc/sec: 2163.18
//
Query:       EEA22576.1  [L=203]
Description: proteasome component Pre8, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.2e-41  141.4   0.1    5.3e-22   78.2   0.0    2.0  2  Proteasome  Proteasome subunit


Domain annotation for each model (and alignments):
>> Proteasome  Proteasome subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.5   0.0     4e-21   7.1e-17      48     123 ..       1      77 [.       1      87 [. 0.91
   2 !   78.2   0.0     3e-26   5.3e-22     114     190 .]      94     167 ..      89     167 .. 0.94

  Alignments for each domain:
  == domain 1  score: 61.5 bits;  conditional E-value: 4e-21
                 EEEEESHHHHHHHHHHHHHHHH.HHHHHHSSGTCHHHHHHHHHHHHHHHHHHCTTTTTSEEEEEEEEETTTEEEEEE CS
  Proteasome  48 vafaGlaaDartlvrraraeaq.lyrlrygrpipverlvarvaaklqaytqrsgrrpfgvslliagvdeeggpeLyq 123
                 +++aG+ +D+r+lv++ar+  +  y+  y++ +p+++lv+ va+ +q+ tq++g+rp+gvslliag+de  +pe+ +
  EEA22576.1   1 MVYAGMGPDYRVLVDKARKVSHtGYKRIYNEYPPTRILVQDVARIVQEATQSGGVRPYGVSLLIAGWDEGVEPEVAE 77 
                 799***************9777258899****************************************999999876 PP

  == domain 2  score: 78.2 bits;  conditional E-value: 3e-26
                 ETTTEEEEEEEETTSEEEEESSEEEESTTHHHHHHHHHHHHSTTBSHHHHHHHHHHHHHHHHHHBTTSCSSEEEEEE CS
  Proteasome 114 deeggpeLyqidpsGsyieekdavaiGsgseaaktalekeykedltleeavelavkalkealerdklsgknievavi 190
                   +ggp+Lyq+dpsGsy+ +k a+aiG+ +++akt+lek+y+e l+le+a+++a+ +lke++e++ ++g+++e++++
  EEA22576.1  94 L-KGGPSLYQVDPSGSYFPWK-ATAIGKSATSAKTFLEKRYTEGLELEDAIHIALLTLKETIEGE-MNGDTVEIGIV 167
                 4.789***************8.*****99**********************************77.********997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (203 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       343  (0.019131); expected 358.6 (0.02)
Passed bias filter:                      318  (0.0177366); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.24s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1521.38
//
Query:       EEA22577.1  [L=333]
Description: RING finger domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    4.9e-09   36.2   3.8    2.2e-08   34.1   0.9    2.3  2  RINGv      RING-variant domain
  ------ inclusion threshold ------
      0.013   15.5   5.9       0.77    9.9   1.5    2.4  2  PHD_4      PHD-finger
       0.05   14.0   6.2       0.49   10.8   2.4    2.3  2  zf-RING_2  Ring finger domain
        0.9   10.4   7.9          1   10.2   0.9    2.1  2  Ima1_N     Ima1 N-terminal domain
        6.2    6.7   8.3         19    5.2   6.5    2.3  2  zf-RING_4  RING/Ubox like zinc-binding domain
        6.4    6.8   8.4        3.6    7.6   5.2    2.0  2  PHD        PHD-finger


Domain annotation for each model (and alignments):
>> RINGv  RING-variant domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.1     0.056   1.7e+02       1       9 [.      63      71 ..      63      79 .. 0.81
   2 !   34.1   0.9   7.4e-12   2.2e-08      13      48 .]     102     142 ..      92     142 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.056
                ETTTTEE-S CS
       RINGv  1 CriCleeee 9 
                CriCle+ +
  EEA22577.1 63 CRICLETVH 71
                ****99865 PP

  == domain 2  score: 34.1 bits;  conditional E-value: 7.4e-12
                 --B-SS--STCCCSB-HHHHHHHHHH.....TCT-SB-TTT CS
       RINGv  13 plispCkCrGslklvHesClekWlde.....keantqCeiC 48 
                  l +pCkC+Gs ++vHe Cl+ W ++     k++  qC  C
  EEA22577.1 102 RLLRPCKCKGSSAYVHEGCLQSWRHAdpsygKRNYWQCPTC 142
                 799********************999887766667779888 PP

>> PHD_4  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   0.2    0.0014       4.1      29      43 ..      59      73 ..      35      83 .. 0.71
   2 ?    9.9   1.5   0.00026      0.77      32      67 ..     108     142 ..      96     143 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0014
       PHD_4 29 slmeCsvCyeivHpe 43
                    C +C e+vHp 
  EEA22577.1 59 PPRMCRICLETVHPT 73
                4567**********6 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.00026
       PHD_4  32 eCsvCyeivHpeClkekegegvvnedlpnsWeCpkC 67 
                  C+  +  vH  Cl++   +   +    n W+Cp+C
  EEA22577.1 108 KCKGSSAYVHEGCLQSW-RHADPSYGKRNYWQCPTC 142
                 68888899******995.4556677889******** PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.1     0.014        42       2      14 ..      62      74 ..      61      81 .. 0.80
   2 ?   10.8   2.4   0.00016      0.49      19      44 .]     107     143 ..      97     143 .. 0.77

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.014
   zf-RING_2  2 eCpICleelssad 14
                +C ICle +++++
  EEA22577.1 62 MCRICLETVHPTS 74
                8*****9987655 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00016
   zf-RING_2  19 lpCgH..v.fhreClerwlrssst........CPlCr 44 
                 ++C+      h+ Cl+ w +  ++        CP+Cr
  EEA22577.1 107 CKCKGssAyVHEGCLQSWRHADPSygkrnywqCPTCR 143
                 4565333436********888888889999******9 PP

>> Ima1_N  Ima1 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.9   0.00034         1      42     102 ..      29      87 ..      21      97 .. 0.70
   2 ?    4.0   1.1     0.028        83      11      27 ..     128     144 ..     120     150 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00034
      Ima1_N  42 peqeeeslneaakkaaaskskskseeaessssssllCskClknqelkvsklaeylpkeded 102
                 p+q+e +   +++++++++s+s+s+++ +++    +C+ Cl+  +   +  ++ylp+  ++
  EEA22577.1  29 PSQTEPEA--TTQNTQTTESTSTSNHKPQPHYPPRMCRICLETVHPTSEPESQYLPSMLQS 87 
                 44444444..4555555555555556888899999*********************65444 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.028
      Ima1_N  11 kvkyeeknsfeCpsCea 27 
                   +y ++n ++Cp+C+ 
  EEA22577.1 128 DPSYGKRNYWQCPTCRF 144
                 567889999******86 PP

>> zf-RING_4  RING/Ubox like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.0      0.24   7.1e+02      23      33 ..      61      71 ..      60      77 .. 0.76
   2 ?    5.2   6.5    0.0062        19      12      47 ..     101     146 ..      97     147 .. 0.79

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.24
   zf-RING_4 23 qiClfCyhril 33
                ++C+ C++ + 
  EEA22577.1 61 RMCRICLETVH 71
                68999988765 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0062
   zf-RING_4  12 dkdlkpCeCg......yqiClfCyhrile....eeegrCPaCreeY 47 
                 ++ l+pC+C+      ++ Cl  ++++      ++  +CP Cr +Y
  EEA22577.1 101 GRLLRPCKCKgssayvHEGCLQSWRHADPsygkRNYWQCPTCRFKY 146
                 56789****8777766889******9998554445779*****999 PP

>> PHD  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.1      0.42   1.3e+03      18      26 ..      63      71 ..      61      78 .. 0.65
   2 ?    7.6   5.2    0.0012       3.6      18      51 ..     109     144 ..     105     145 .. 0.82

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.42
                ETTTSCEEE CS
         PHD 18 CdgCkrwfH 26
                C  C +++H
  EEA22577.1 63 CRICLETVH 71
                555555555 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0012
                 ETTTSCEEETTTSSSTHSHHSHHSS..TBSSTTTHT CS
         PHD  18 CdgCkrwfHqkClkppleseekpeg..ewlCekCke 51 
                 C+g +  +H  Cl+     ++   +   w+C++C+ 
  EEA22577.1 109 CKGSSAYVHEGCLQSWRHADPSYGKrnYWQCPTCRF 144
                 8888899*******9877666555577*******86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (333 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1191  (0.0664287); expected 358.6 (0.02)
Passed bias filter:                      768  (0.0428356); expected 358.6 (0.02)
Passed Vit filter:                        69  (0.00384851); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.53u 0.24s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 2337.17
//
Query:       EEA22578.1  [L=287]
Description: RING finger domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.3e-09   36.7   3.8    1.8e-08   34.4   0.9    2.3  2  RINGv      RING-variant domain
     0.0096   16.0   5.9       0.62   10.2   1.5    2.3  2  PHD_4      PHD-finger
  ------ inclusion threshold ------
      0.035   14.5   6.2       0.39   11.1   2.4    2.3  2  zf-RING_2  Ring finger domain
       0.61   10.9   7.9        0.8   10.6   0.9    2.1  2  Ima1_N     Ima1 N-terminal domain
        4.1    7.3   8.1         14    5.6   6.4    2.3  2  zf-RING_4  RING/Ubox like zinc-binding domain
        4.7    7.2   8.4        2.9    7.9   5.2    2.0  2  PHD        PHD-finger


Domain annotation for each model (and alignments):
>> RINGv  RING-variant domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.1     0.047   1.4e+02       1       9 [.      63      71 ..      63      79 .. 0.80
   2 !   34.4   0.9     6e-12   1.8e-08      13      48 .]     102     142 ..      92     142 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.047
                ETTTTEE-S CS
       RINGv  1 CriCleeee 9 
                CriCle+ +
  EEA22578.1 63 CRICLETVH 71
                ****99865 PP

  == domain 2  score: 34.4 bits;  conditional E-value: 6e-12
                 --B-SS--STCCCSB-HHHHHHHHHH.....TCT-SB-TTT CS
       RINGv  13 plispCkCrGslklvHesClekWlde.....keantqCeiC 48 
                  l +pCkC+Gs ++vHe Cl+ W ++     k++  qC  C
  EEA22578.1 102 RLLRPCKCKGSSAYVHEGCLQSWRHAdpsygKRNYWQCPTC 142
                 799********************999887766667779888 PP

>> PHD_4  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.8   0.2    0.0011       3.4      29      43 ..      59      73 ..      35      83 .. 0.71
   2 !   10.2   1.5   0.00021      0.62      32      67 ..     108     142 ..      96     143 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0011
       PHD_4 29 slmeCsvCyeivHpe 43
                    C +C e+vHp 
  EEA22578.1 59 PPRMCRICLETVHPT 73
                4567**********6 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.00021
       PHD_4  32 eCsvCyeivHpeClkekegegvvnedlpnsWeCpkC 67 
                  C+  +  vH  Cl++   +   +    n W+Cp+C
  EEA22578.1 108 KCKGSSAYVHEGCLQSW-RHADPSYGKRNYWQCPTC 142
                 68888899******995.4556677889******** PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8   0.1     0.012        35       2      14 ..      62      74 ..      61      81 .. 0.80
   2 ?   11.1   2.4   0.00013      0.39      19      44 .]     107     143 ..      96     143 .. 0.77

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.012
   zf-RING_2  2 eCpICleelssad 14
                +C ICle +++++
  EEA22578.1 62 MCRICLETVHPTS 74
                8*****9987655 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00013
   zf-RING_2  19 lpCgH..v.fhreClerwlrssst........CPlCr 44 
                 ++C+      h+ Cl+ w +  ++        CP+Cr
  EEA22578.1 107 CKCKGssAyVHEGCLQSWRHADPSygkrnywqCPTCR 143
                 4565333436********888888889999******9 PP

>> Ima1_N  Ima1 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.9   0.00027       0.8      39     102 ..      28      87 ..      21      97 .. 0.70
   2 ?    4.3   1.1     0.023        69      11      27 ..     128     144 ..     120     150 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00027
      Ima1_N  39 deipeqeeeslneaakkaaaskskskseeaessssssllCskClknqelkvsklaeylpkeded 102
                 +  p+q+e +   +++++++++s+s+s+++ +++    +C+ Cl+  +   +  ++ylp+  ++
  EEA22578.1  28 E--PSQTEPEA--TTQNTQTTESTSTSNHKPQPHYPPRMCRICLETVHPTSEPESQYLPSMLQS 87 
                 3..44444444..4555555555555556888899999*********************65444 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.023
      Ima1_N  11 kvkyeeknsfeCpsCea 27 
                   +y ++n ++Cp+C+ 
  EEA22578.1 128 DPSYGKRNYWQCPTCRF 144
                 567889999******86 PP

>> zf-RING_4  RING/Ubox like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0       0.2     6e+02      23      33 ..      61      71 ..      60      77 .. 0.76
   2 ?    5.6   6.4    0.0046        14      12      47 ..     101     146 ..      97     147 .. 0.79

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.2
   zf-RING_4 23 qiClfCyhril 33
                ++C+ C++ + 
  EEA22578.1 61 RMCRICLETVH 71
                68999988765 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0046
   zf-RING_4  12 dkdlkpCeCg......yqiClfCyhrile....eeegrCPaCreeY 47 
                 ++ l+pC+C+      ++ Cl  ++++      ++  +CP Cr +Y
  EEA22578.1 101 GRLLRPCKCKgssayvHEGCLQSWRHADPsygkRNYWQCPTCRFKY 146
                 56789****8777766889******9998554445779*****999 PP

>> PHD  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.1      0.36   1.1e+03      18      26 ..      63      71 ..      61      78 .. 0.65
   2 ?    7.9   5.2   0.00097       2.9      18      51 ..     109     144 ..     105     145 .. 0.82

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.36
                ETTTSCEEE CS
         PHD 18 CdgCkrwfH 26
                C  C +++H
  EEA22578.1 63 CRICLETVH 71
                555555555 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.00097
                 ETTTSCEEETTTSSSTHSHHSHHSS..TBSSTTTHT CS
         PHD  18 CdgCkrwfHqkClkppleseekpeg..ewlCekCke 51 
                 C+g +  +H  Cl+     ++   +   w+C++C+ 
  EEA22578.1 109 CKGSSAYVHEGCLQSWRHADPSYGKrnYWQCPTCRF 144
                 8888899*******9877666555577*******86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (287 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       851  (0.047465); expected 358.6 (0.02)
Passed bias filter:                      511  (0.0285013); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2021.70
//
Query:       EEA22579.1  [L=504]
Description: hypothetical protein PMAA_092040 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (504 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       535  (0.0298399); expected 358.6 (0.02)
Passed bias filter:                      455  (0.0253779); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.41
# Mc/sec: 3716.90
//
Query:       EEA22580.1  [L=482]
Description: adenylosuccinate lyase Ade13, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      6e-23   81.7   0.0    1.2e-22   80.8   0.0    1.4  1  Lyase_1   Lyase
    1.3e-17   64.1   0.1    7.8e-17   61.6   0.0    2.3  2  ADSL_C    Adenylosuccinate lyase C-terminus


Domain annotation for each model (and alignments):
>> Lyase_1  Lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.8   0.0   1.3e-26   1.2e-22      52     303 ..      56     301 ..      17     308 .. 0.80

  Alignments for each domain:
  == domain 1  score: 80.8 bits;  conditional E-value: 1.3e-26
                 HHHHHHHHHHCHCHHCGGHHHBSSSSSHHHHHHHHHHHHHHHHTTHSSGIIIIITTT--HHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHTT CS
     Lyase_1  52 aiikaldevleegklddqfvlkviqegsgtavnmnlnevigellgekvepndkvhtgqSsnDqvpTalrlalkkalsekLlpaleqLidalkekakefk 150
                 ai +    v+    +dd+f+++  +e+      m+  +  g       ++++ +h g++s  + + a  ++l++ l + L+p+l + id l + a e+k
  EEA22580.1  56 AIAQMKAHVII---QDDEFAVAAEEEKRRRHDVMAHVKAFG---DVAPAASGMIHVGATSCFVTDNADLIFLRDGL-DILIPKLATVIDKLAAFAMEYK 147
                 33333333333...456777777666655444443333344...256899***********99999999*******.66******************** PP

                 T-EEEEEETTEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHTCEETTTTTTTSSTTTSCCTHHHHHHHHHH..HHHCST.EESSSHHHHHHC-HHHH CS
     Lyase_1 151 dvvkiGrThlqdAtPvtlgqelsayaealerdrerlkellkrllvellgggtavgtglnadpefaelvakela..kvtglp.vkapnsfeavsdrDavv 246
                 d + +G+Th+q+A+ vt g+  + + + l +d+ +l++++k l+   ++g t++ + +    + +++ +++l     ++ +  +a  +  ++ +r   v
  EEA22580.1 148 DLPCLGFTHGQPAQLVTVGKRAALWLQDLLMDLRNLERARKDLRFRGVKGTTGTQASFLQIFNGDHAKVEKLDelVTEKAGfESAFIISGQTYSRKIDV 246
                 **************************************************8887766543333366777777742234445555666778999****** PP

                 HHHHHHHHHHHHHHHHHHHHHHHTSTTTSSEEEEGCCTSSC-TTSTTTEBTHHHHHH CS
     Lyase_1 247 ellgalkllatsLskfaeDlrllssgeaglvelslaesepGSSiMPgKvNPvqlEll 303
                 +++ al  +     +++ D+r l+   + +ve+ + + ++GSS M  K+NP  +E l
  EEA22580.1 247 DVANALGSFGSTCERIGGDIRHLAM--LKEVEEPFEKDQIGSSAMAYKRNPMRSERL 301
                 *************************..**************************9976 PP

>> ADSL_C  Adenylosuccinate lyase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.1      0.44   3.9e+03      38      64 ..      63      90 ..      52      95 .. 0.68
   2 !   61.6   0.0   8.7e-21   7.8e-17       1      73 []     375     457 ..     375     457 .. 0.96

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.44
                HHHHT-HHHH.CHHCHHHHHT-GGGCCT CS
      ADSL_C 38 elLaadpevk.kseeeldalfdpayylg 64
                 ++ +d+e++ ++eee ++  d  ++++
  EEA22580.1 63 HVIIQDDEFAvAAEEEKRRRHDVMAHVK 90
                5677888888557777777777777766 PP

  == domain 2  score: 61.6 bits;  conditional E-value: 8.7e-21
                 TGGGHHHHHHHHH.HTH-HHHHHHHHHHHHHHHHHC.........HHHHHHT-HHHHC.HHCHHHHHT-GGGCCTTHHHHHHHH CS
      ADSL_C   1 GlifservllaLv.kglgReeAyelVqeaamkawee.........llelLaadpevkk.seeeldalfdpayylgsadeivdrv 73 
                 +++++e++++a+v kgl+R++A+e ++ ++++a ++         l+e+++  + ++     eld l+dp++++g+a+++v+++
  EEA22580.1 375 PFMATENIIMACVaKGLSRQDAHEEIRVLSHQASDNvkkqgksndLIERIRRTEFFAPiIG-ELDSLLDPSTFIGRAPQQVEKF 457
                 79***********88******************************************7455.9******************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (482 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       495  (0.0276089); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.50
# Mc/sec: 2903.18
//
Query:       EEA22581.1  [L=626]
Description: Exocyst complex component Exo70, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.6e-83  280.1   0.0    6.8e-83  278.8   0.0    1.6  2  Exo70          Exo70 exocyst complex subunit
  ------ inclusion threshold ------
      0.012   15.5   0.0        1.1    9.2   0.0    3.1  3  DUF448         Protein of unknown function (DUF448)
      0.057   13.4   0.2      0.057   13.4   0.2    2.1  2  Bap31_Bap29_C  Bap31/Bap29 cytoplasmic coiled-coil domain
      0.068   11.1   1.1       0.14   10.1   1.1    1.4  1  Prominin       Prominin
      0.083   13.1   1.7       0.46   10.7   0.0    2.8  3  DUF4355        Domain of unknown function (DUF4355)
        0.2   11.9   0.3         17    5.8   0.0    3.5  3  MHB            Haemophore, haem-binding
       0.49   10.7   2.2        2.1    8.7   0.7    2.9  3  FliS           Flagellar protein FliS
        7.7    7.1   7.3        7.9    7.0   0.1    3.6  4  FadA           Adhesion protein FadA


Domain annotation for each model (and alignments):
>> Exo70  Exo70 exocyst complex subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0      0.51   1.1e+03      66     109 ..      97     139 ..      56     161 .. 0.59
   2 !  278.8   0.0     3e-86   6.8e-83       1     374 [.     245     622 ..     245     624 .. 0.98

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.51
       Exo70  66 speklfklLdmyealsdllpeleslfsgeaksevkaeleellkk 109
                 +++ l  +L  ++++  +l++l+s    +++++  +e+ +ll+ 
  EEA22581.1  97 QSAGLSQYLAALKRIDYALQNLNSTNL-KSNQQAITEFTSLLNF 139
                 556666777777777777777775554.3444555555555542 PP

  == domain 2  score: 278.8 bits;  conditional E-value: 3e-86
       Exo70   1 krwikayktavkvlfasErrlleqifgeseseresvfaeiakesitellqllrefgeavakkskrspeklfklLdmyealsdllpeleslfsgeaksev 99 
                 +++i  y+ a+++++  E++ + qi++  ++++   ++++++ +++e+ ++lre+++ ++ ++   +++++++ +++e ++ ++ ++++ ++     e+
  EEA22581.1 245 TNGIGVYSSALEGFISVEHDAIVQIYT--GENQGRALQATCRSALAEFSKTLRELNQYIKANL--MTDCFLAF-EIIEIVTAMSYRIDAKTG-----EL 333
                 589***********************9..9******************************999..********.***************998.....6* PP

       Exo70 100 kaeleellkklsetakslleefeesikkdssk.spvppdggvheltrnvmnylrkLleykdtlssllkdlkdeswssasssqssssesssadgesllal 197
                 k+ + e+l++++etaks+l+e++e++kk+++  + +ppdgg+ +l+ +vm+ l +L+ y+ +l s+l +l+d++w+s+s+s+s++  + s d+++l+++
  EEA22581.1 334 KSLFIEALRPIRETAKSSLSELLEETKKKAAAyTVLPPDGGTVPLVNEVMSSLTTLTGYSGPLASILTSLGDGNWRSKSQSASTTPLDVSPDSQTLFSH 432
                 *****************************999******************************************************************* PP

       Exo70 198 fladlisaLesnLeakakl.ykdkslqgiFlmNNlhyilqkvkrs.elklll.gddwlrkhekkikqyaksYeresWskvlslLkdeglts........ 285
                 f+ d+++aL+++Lea+ ++ y+ k++ g+F+ N ++++ ++++ s +l+ +l ++d ++k++  +k+ +++Y +e+W++  ++L d ++ts        
  EEA22581.1 433 FILDMVEALMNSLEARGRAtYRSKAVLGVFISNTFCVVDRSIRASsDLSRYLaSPDSIAKIDAFRKRGTSAY-LEAWRETNQYLLDVQYTSrggprsst 530
                 ****************************************************99******************.9************************* PP

       Exo70 286 .......sskklssskekeqikekfkkFnsaFeelvrkqkswkvpDpeLReeLrreikekvipaYrkFlerykevdftknpekyvkytpedlenlL 374
                         +k+ls sk+k++ikekfk+Fn+ F+ lv+++++ ++ ++e+R  L re++ ++ p+Y +F++ry+e d+   + kyvky++  ++++L
  EEA22581.1 531 qqtdsaqVVKSLS-SKDKDAIKEKFKSFNATFDSLVTQHRQLHM-EREVRGALGREVQGVLEPLYGRFHDRYHEIDKG--RGKYVKYDKAAFSAQL 622
                 *****97777777.******************************.9***************************99988..66**********9998 PP

>> DUF448  Protein of unknown function (DUF448)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0         2   4.5e+03      36      51 ..     212     227 ..     209     233 .. 0.83
   2 ?    9.2   0.0   0.00047       1.1       3      45 ..     468     509 ..     467     517 .. 0.89
   3 ?    2.3   0.0      0.07   1.6e+02      35      49 ..     605     619 ..     595     624 .. 0.83

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 2
      DUF448  36 GRGaYvcpseecleka 51 
                  RG Y++ s + l+ a
  EEA22581.1 212 TRGPYITSSLQNLAIA 227
                 69*****999999876 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00047
      DUF448   3 CivcrekkpkkeLiRvvrtpegevvlDltgklpGRGaYvcpse 45 
                 C+v r  +  ++L R  ++p++   +D   ++ G +aY+ + +
  EEA22581.1 468 CVVDRSIRASSDLSRYLASPDSIAKID-AFRKRGTSAYLEAWR 509
                 *********************9899**.6678******98655 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.07
      DUF448  35 pGRGaYvcpseecle 49 
                 +GRG Yv+ ++++++
  EEA22581.1 605 KGRGKYVKYDKAAFS 619
                 8*********99886 PP

>> Bap31_Bap29_C  Bap31/Bap29 cytoplasmic coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.1   0.5       7.6   1.7e+04       6      16 ..     352     362 ..     351     365 .. 0.61
   2 ?   13.4   0.2   2.5e-05     0.057      13      42 ..     543     573 ..     531     580 .. 0.86

  Alignments for each domain:
  == domain 1  score: -4.1 bits;  conditional E-value: 7.6
  Bap31_Bap29_C   6 LkkeLkkkkkD 16 
                    L + L+++kk 
     EEA22581.1 352 LSELLEETKKK 362
                    66667776665 PP

  == domain 2  score: 13.4 bits;  conditional E-value: 2.5e-05
  Bap31_Bap29_C  13 kkkDlealKkQaeglakEYDrLadehskl.d 42 
                    ++kD++a+K++ ++ ++ +D L ++h +l  
     EEA22581.1 543 SSKDKDAIKEKFKSFNATFDSLVTQHRQLhM 573
                    459*************************962 PP

>> Prominin  Prominin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   1.1   6.2e-05      0.14     569     685 ..       9     132 ..       3     163 .. 0.68

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 6.2e-05
    Prominin 569 teeiqkelenlkvdlsnlelLteeerkdLeklresg..lskihsslyleqlckkltkvnletlaekleelanelsngk...............knlkqs 650
                 ++e++ e+e l  +l++l++Lt++ + +L+ l++sg  +++     y +  + ++t+ n++ + e +++l + l+ +                ++   +
  EEA22581.1   9 YAEESAEVEVLYANLDKLKVLTKKIQGSLDRLETSGkvVKDAIGPIYSNTQTLQITNSNIDRVIEAIDKLRKPLDAKGkeegiiragpqsaglSQYLAA 107
                 368999****************************98656777778898888999******************998776788886665544444233333 PP

    Prominin 651 lkneaqdlraiqqelvlplessvkklkksvkklde 685
                 lk+  + l++++++          +lk++ +++ e
  EEA22581.1 108 LKRIDYALQNLNST----------NLKSNQQAITE 132
                 33333333333333..........33333333332 PP

>> DUF4355  Domain of unknown function (DUF4355)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0      0.74   1.7e+03      95     115 ..      59      79 ..      57      81 .. 0.84
   2 ?   -1.8   0.1       1.5   3.4e+03      19      37 ..     347     364 ..     320     369 .. 0.66
   3 ?   10.7   0.0   0.00021      0.46      81     120 ..     531     570 ..     511     574 .. 0.91

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.74
     DUF4355  95 edaeetkknvetfkelfnkav 115
                 ++   t++n++   e+++k +
  EEA22581.1  59 QTLQITNSNIDRVIEAIDKLR 79 
                 56678************9975 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 1.5
     DUF4355  19 tkknklekeledeikkeak 37 
                 t+k++l + le+ + k+a+
  EEA22581.1 347 TAKSSLSELLEETK-KKAA 364
                 45555555555544.4444 PP

  == domain 3  score: 10.7 bits;  conditional E-value: 0.00021
     DUF4355  81 ekkipiellnlvvgedaeetkknvetfkelfnkavekave 120
                 ++  ++++++ ++++d++ +k++ ++f++ f++ v ++++
  EEA22581.1 531 QQTDSAQVVKSLSSKDKDAIKEKFKSFNATFDSLVTQHRQ 570
                 55667799***************************99876 PP

>> MHB  Haemophore, haem-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.0      0.22   4.9e+02      17      52 ..      99     134 ..      94     149 .. 0.84
   2 ?    5.8   0.0    0.0075        17       7      47 ..     489     529 ..     486     535 .. 0.80
   3 ?   -0.3   0.0      0.58   1.3e+03      28      51 ..     534     557 ..     530     563 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.22
         MHB  17 astsaYLdthPdvnqaltslkgqprdqaraavkaYf 52 
                 a  s+YL++   ++ al++l++ + +  ++a++++ 
  EEA22581.1  99 AGLSQYLAALKRIDYALQNLNSTNLKSNQQAITEFT 134
                 667999999999999999999999888888888775 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0075
         MHB   7 dlarvvsgVaastsaYLdthPdvnqaltslkgqprdqaraa 47 
                  +a++ +  +  tsaYL++  ++nq l +++  +r   r++
  EEA22581.1 489 SIAKIDAFRKRGTSAYLEAWRETNQYLLDVQYTSRGGPRSS 529
                 677888888889***************99998888555554 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.58
         MHB  28 dvnqaltslkgqprdqaraavkaY 51 
                 d  q+++sl+++++d++++++k++
  EEA22581.1 534 DSAQVVKSLSSKDKDAIKEKFKSF 557
                 667999**************9998 PP

>> FliS  Flagellar protein FliS
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   0.7   0.00092       2.1      37     105 ..      57     138 ..      21     149 .. 0.81
   2 ?   -3.3   0.0       4.7   1.1e+04      68      85 ..     288     305 ..     278     307 .. 0.64
   3 ?   -3.0   0.0       3.9   8.7e+03      68     107 ..     551     592 ..     538     598 .. 0.63

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00092
                 HTTTHHHHHHHHHHHHHHHHHHHHTCCTTTSC...........HHHHHHHHH..HHHHHHHHHHHHHCT-HHHHHHHHHHHH CS
        FliS  37 eekdiekkgeaiskaqdIiseLrasLdlekgg...........eiaknLaal..Ydyiirrlleanlkkdaekldeviklle 105
                 +++ ++ ++ +i ++++ i++Lr+ Ld + ++            +++ Laal   dy +++l   nlk +++++ e  +ll+
  EEA22581.1  57 NTQTLQITNSNIDRVIEAIDKLRKPLDAKGKEegiiragpqsaGLSQYLAALkrIDYALQNLNSTNLKSNQQAITEFTSLLN 138
                 4566788999*****************9766456888898888777888877545899999*******99999999999885 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 4.7
                 CHHHHHHHHHHHHHHHHH CS
        FliS  68 geiaknLaalYdyiirrl 85 
                  e +k+L++l +yi  +l
  EEA22581.1 288 AEFSKTLRELNQYIKANL 305
                 367777777777776666 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 3.9
                 CHHHHHHHHHHHHHHHHHHHHHHCT-H..HHHHHHHHHHHHH CS
        FliS  68 geiaknLaalYdyiirrlleanlkkda..ekldeviklleel 107
                 +e  k+++a +d ++++  + ++++++  +  +ev+++le+l
  EEA22581.1 551 KEKFKSFNATFDSLVTQHRQLHMEREVrgALGREVQGVLEPL 592
                 455566666777777777777777666555556777777766 PP

>> FadA  Adhesion protein FadA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.1    0.0035       7.9      17      57 ..       6      46 ..       2      87 .. 0.84
   2 ?    2.1   0.2      0.12   2.8e+02      63      96 ..     103     137 ..     101     139 .. 0.83
   3 ?   -3.6   0.0       7.3   1.6e+04      67      84 ..     286     303 ..     277     304 .. 0.70
   4 ?   -1.1   0.1       1.2   2.8e+03      42      72 ..     548     569 ..     528     576 .. 0.57

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0035
        FadA 17 eqrykkekakaeaaaaklakkkelkakieeklakleadsev 57
                + +y++e a+ e   a+l+k k l +ki+  l++le++ +v
  EEA22581.1  6 NTTYAEESAEVEVLYANLDKLKVLTKKIQGSLDRLETSGKV 46
                567*******************************9876554 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.12
        FadA  63 eYkellkeyksllkelek.eikekekkianfeklk 96 
                 +Y   lk+ + +l++l++ + k++++ i +f++l+
  EEA22581.1 103 QYLAALKRIDYALQNLNStNLKSNQQAITEFTSLL 137
                 6778899999999999863689*********9886 PP

  == domain 3  score: -3.6 bits;  conditional E-value: 7.3
        FadA  67 llkeyksllkelekeike 84 
                  l e+++ l el++ ik 
  EEA22581.1 286 ALAEFSKTLRELNQYIKA 303
                 566777777777777765 PP

  == domain 4  score: -1.1 bits;  conditional E-value: 1.2
        FadA  42 akieeklakleadsevrfykdeYkellkeyk 72 
                 ++i         +++ + +  ++++l+ + +
  EEA22581.1 548 DAI---------KEKFKSFNATFDSLVTQHR 569
                 333.........4556666666666666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (626 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       925  (0.0515924); expected 358.6 (0.02)
Passed bias filter:                      722  (0.04027); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.87u 0.36s 00:00:01.23 Elapsed: 00:00:00.56
# Mc/sec: 3341.84
//
Query:       EEA22582.1  [L=845]
Description: phospholipase A2 (PlaA), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.7e-26   90.4   0.0      2e-25   89.2   0.0    1.6  1  PLA2_B    Lysophospholipase catalytic domain


Domain annotation for each model (and alignments):
>> PLA2_B  Lysophospholipase catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.2   0.0   1.1e-29     2e-25       1     351 [.     213     578 ..     213     585 .. 0.71

  Alignments for each domain:
  == domain 1  score: 89.2 bits;  conditional E-value: 1.1e-29
      PLA2_B   1 iaiavSGGGyramltgaGvlkAldsRtdnatglgGlLqsatYlaGlsGgsWlvgslavNnftsvqelskkkeddsvweleksilnpeglelvknikryd 99 
                 ia+ +SGGG+ra++ g+G   A +        ++Gl ++ tY aG+sG+ Wl+  l +N      ++    ++ +     +  + p+ l+l++++   +
  EEA22582.1 213 IAMCGSGGGLRALVAGSGSYLASQ--------EAGLWDCVTYTAGVSGSCWLLT-L-YNSSLGNRDFLRLVGHLKSRLGVHIAFPPKALNLLTTAPTNK 301
                 7999**************999988........9*******************95.6.366666666666566666666666677788888776665544 PP

      PLA2_B 100 eivdevek..KkdagfnvsltDiwGralseklve..aeeggvnltlsslkdaekfqeaemplPiivadgrk..................pgetvinlNa 176
                  +   + +  K d + n  l Di+G +l+ +l+    e +  + tl   ++ + +q++  plPi +a   +                  ++e   ++  
  EEA22582.1 302 YLLSGLVEklKGDPDANFGLVDIYGLLLAARLLVprGELDVSDRTLKLSNQRDYVQDGSNPLPIYTAVRHEipapdkeeikgrravekvKEEALKEAWF 400
                 45555544123455667789********99987623233334444444456699*************98888998888888887775554444455556 PP

      PLA2_B 177 tvfEfsPyelgswdaklnsFvpveylGtklsnGtvvkkgkc....vagfdnaGflmgtsstlFnevlleinsts.......mlesllkellkkllkdls 264
                 ++fEf+Pye+    ++ ++ +p+  +G ++  G+    + c     +    +G++++++ +   +   e+            ++sl++ + ++l+k   
  EEA22582.1 401 QWFEFTPYEFF--CEEFGAGIPMWAVGRHFYGGRDQPPNTCpvpeLRIPALMGIWGSAFCATLAHYYKEVRPVVkglagfgGIDSLIEGKSDELIKVHP 497
                 89*******96..9*******************998888884222334457788877776655555555444432222333333444444444433333 PP

      PLA2_B 265 edsedisqyapnpfkdaeee.nqnatqsivesktLdlvdggedgqniplvpllqkerevdvifaldnsadteeswpdgvslvatyeRv 351
                  d    ++++ n   +++e   +   +s  ++++L l+d g   +n+p+ pll++ r++d+i+a+d+sad ++   +  ++v+ y R+
  EEA22582.1 498 FD---PASIP-NYILGMKEKlPSSCPESALNDPHLRLMDAGMS-NNLPIYPLLRPGRDIDIIVAFDASADIKQ--ENWLAVVDGYVRQ 578
                 33...33333.44445443326666679*************86.69************************998..5667788888877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (845 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       851  (0.047465); expected 358.6 (0.02)
Passed bias filter:                      571  (0.0318478); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.80u 0.34s 00:00:01.14 Elapsed: 00:00:00.53
# Mc/sec: 4794.36
//
Query:       EEA22583.1  [L=504]
Description: phosphoinositide phosphatase Pten/Tep1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.6e-10   38.9   0.0    1.3e-09   38.0   0.0    1.4  1  DSPc            Dual specificity phosphatase, catalytic domai
  ------ inclusion threshold ------
      0.019   14.6   0.0       0.04   13.5   0.0    1.5  1  Y_phosphatase   Protein-tyrosine phosphatase
      0.029   14.3   0.0      0.083   12.8   0.0    1.7  2  Y_phosphatase3  Tyrosine phosphatase family


Domain annotation for each model (and alignments):
>> DSPc  Dual specificity phosphatase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.0   0.0   2.2e-13   1.3e-09      71     117 ..      22      68 ..      15      74 .. 0.86

  Alignments for each domain:
  == domain 1  score: 38.0 bits;  conditional E-value: 2.2e-13
                 HTT-EEEEEESSSSSHHHHHHHHHHHHHHTSCHHHHHHHHHHHSTT- CS
        DSPc  71 qkgkkvlVHCqaGisRSatliiaYlmktknlslneayeflkerrpai 117
                 ++++  +VHC+aG  RS+t+++ Yl++++++++++a++ + err ++
  EEA22583.1  22 KEKRVAVVHCKAGKGRSGTVACSYLISQEGWKMEDALQRFTERRMRV 68 
                 44444579**********************************99765 PP

>> Y_phosphatase  Protein-tyrosine phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   6.6e-06      0.04     167     193 ..      21      47 ..       2      64 .. 0.79

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 6.6e-06
                    STTSS-EEEECSSSSHHHHHHHHHHHH CS
  Y_phosphatase 167 eaksgpvvVhCsaGvgRtgtfvaldil 193
                    ++++   vVhC+aG gR+gt+++  ++
     EEA22583.1  21 KKEKRVAVVHCKAGKGRSGTVACSYLI 47 
                    4456778*************8876554 PP

>> Y_phosphatase3  Tyrosine phosphatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   1.4e-05     0.083     119     140 ..      22      44 ..       9      61 .. 0.81
   2 ?   -2.7   0.0      0.77   4.6e+03     183     219 ..     399     435 ..     360     442 .. 0.56

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.4e-05
  Y_phosphatase3 119 dee.pvlfHCtaGKDRTGvlaal 140
                     +e+  +++HC aGK R G +a  
      EEA22583.1  22 KEKrVAVVHCKAGKGRSGTVACS 44 
                     433578************98864 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 0.77
  Y_phosphatase3 183 leellsvrpeyleaaldaieekygsvegYlreelgls 219
                      ++l ++ + ++++a ++  +   s+ + +r+elgl 
      EEA22583.1 399 EKALNGTTHPFIAHASASTAAAVTSAVKRVRRELGLR 435
                     4455555555555555555555555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (504 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       769  (0.0428914); expected 358.6 (0.02)
Passed bias filter:                      441  (0.024597); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.59u 0.26s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 3374.04
//
Query:       EEA22584.1  [L=490]
Description: pentatricopeptide repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.6e-13   50.0   0.0      0.012   15.7   0.0    5.1  5  PPR_2     PPR repeat family
    1.8e-09   37.3   0.1      0.014   14.8   0.0    3.6  3  PPR_long  Pentacotripeptide-repeat region of PRORP
    8.7e-09   35.1   0.2        1.2    9.5   0.0    6.1  6  PPR       PPR repeat
      7e-08   32.4   0.7       0.27   11.3   0.0    5.8  7  PPR_3     Pentatricopeptide repeat domain
  ------ inclusion threshold ------
      0.028   13.7   3.1      0.028   13.7   0.2    2.4  4  PET122    PET122
      0.032   14.6   0.6        3.3    8.1   0.4    3.1  3  HEAT_2    HEAT repeats
      0.058   14.2   0.6         48    5.1   0.0    4.7  5  TPR_14    Tetratricopeptide repeat
      0.069   12.3   0.0         19    4.3   0.0    2.9  3  ECSIT     Evolutionarily conserved signalling intermediate in


Domain annotation for each model (and alignments):
>> PPR_2  PPR repeat family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.2   0.0    0.0055        12      15      41 ..      94     120 ..      84     128 .. 0.86
   2 !   13.9   0.0   2.1e-05     0.047       6      49 ..     155     198 ..     153     199 .. 0.81
   3 ?   -0.2   0.0      0.52   1.2e+03       9      28 ..     193     212 ..     191     222 .. 0.82
   4 !    7.0   0.0    0.0029       6.5       9      35 ..     299     325 ..     296     337 .. 0.87
   5 !   15.7   0.0   5.5e-06     0.012       2      45 ..     408     451 ..     407     455 .. 0.94

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0055
       PPR_2  15 kkgkveeAfklfneMkkrglePnsyTy 41 
                 ++g v+    l+ eM ++g++ +s T 
  EEA22584.1  94 QHGSVKNVRNLLREMAEQGITADSATL 120
                 578899999***************995 PP

  == domain 2  score: 13.9 bits;  conditional E-value: 2.1e-05
       PPR_2   6 yNtlIsglckkgkveeAfklfneMkkrglePnsyTysilikglc 49 
                 + ++ +gl++++++e A++ +++M+++g+      +s li  lc
  EEA22584.1 155 WHHVVAGLLRENQLELALDRLEQMERKGILIEQWLHSLLIYKLC 198
                 667899**********************9766655555555555 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 0.52
       PPR_2   9 lIsglckkgkveeAfklfne 28 
                 lI  lc   +++eA++l   
  EEA22584.1 193 LIYKLCDVDEFSEALRLIRS 212
                 67789999********9876 PP

  == domain 4  score: 7.0 bits;  conditional E-value: 0.0029
       PPR_2   9 lIsglckkgkveeAfklfneMkkrgle 35 
                 l + ++++ ++++Af++  +M k++++
  EEA22584.1 299 LVQVYARNADIKSAFEIVYQMHKHNVP 325
                 7899********************996 PP

  == domain 5  score: 15.7 bits;  conditional E-value: 5.5e-06
       PPR_2   2 dvvtyNtlIsglckkgkveeAfklfneMkkrglePnsyTysili 45 
                 ++ t+N lIs + +  +++ +  + +eM   g++P+  T  +li
  EEA22584.1 408 NTDTFNNLISLCHQTSRPDICTFFAKEMAASGVPPDQRTLETLI 451
                 889*************************************9999 PP

>> PPR_long  Pentacotripeptide-repeat region of PRORP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.1   0.0   0.00071       1.6      25     158 ..      58     185 ..      36     196 .. 0.73
   2 !    9.5   0.0   0.00026      0.59      93     135 ..     296     338 ..     273     345 .. 0.83
   3 !   14.8   0.0   6.2e-06     0.014      68     156 ..     386     475 ..     365     481 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00071
                 T-HHHHHHHHHHHHH.SSS---HHHHHHHHHHHHHC.HCSTTTHHHHHHHHHHHHHHHHHTT----HHHHHHHHHHHHHTT-HHHHHHHHHHHHHH-S- CS
    PPR_long  25 kDaaaAlelydkava.egvrlaqyhynvllylcskaeaaseskknkalargfevfeamkakgvspnEatvtalarlaaakedgdlafelvkemekagvs 122
                  D+++ + + ++  + + v+ ++ hy++  yl+++ +++     + +++++++  ++m ++g+++  at+ a   + a + d  l  e+++ +++  +s
  EEA22584.1  58 IDISKTITILKELLQrHRVTPTTRHYKA--YLLTNIDRQ-----HGSVKNVRNLLREMAEQGITADSATLHAALEVLAVHPDYLLRQEVIEALRARWLS 149
                 4778888888887763558888888886..677666433.....457899***************************9999999999999999876555 PP

                 --HHHHHHHHHHHHHTT-HHHHHHHHHHHHHCT--- CS
    PPR_long 123 PrLRsyaPaLaayckagdadkaleveehlkasgvel 158
                      +  + a + + ++++ al   e+++ +g+ +
  EEA22584.1 150 LSPAGWHHVVAGLLRENQLELALDRLEQMERKGILI 185
                 444566667777777777777777777777666655 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00026
                 HHHHHHHHHHTT-HHHHHHHHHHHHHH-S---HHHHHHHHHHH CS
    PPR_long  93 vtalarlaaakedgdlafelvkemekagvsPrLRsyaPaLaay 135
                 +  l+++ a ++d   afe+v +m+k +v  +  +  P+L++ 
  EEA22584.1 296 YGKLVQVYARNADIKSAFEIVYQMHKHNVPIKPETTRPILQSM 338
                 6679999*********************999999999999875 PP

  == domain 3  score: 14.8 bits;  conditional E-value: 6.2e-06
                 HHHHHHHHHHHHHHHH.TT----HHHHHHHHHHHHHTT-HHHHHHHHHHHHHH-S---HHHHHHHHHHHHHTT-HHHHHHHHHHHHHCT- CS
    PPR_long  68 nkalargfevfeamka.kgvspnEatvtalarlaaakedgdlafelvkemekagvsPrLRsyaPaLaayckagdadkaleveehlkasgv 156
                 ++a++ +  +++++   +++ +n  t+  l+ l+ +++  d +    kem+++gv P  R+ + ++    ++g+   a +  + l+a+g 
  EEA22584.1 386 SRAIEVAVSIYKDLFDiCASGANTDTFNNLISLCHQTSRPDICTFFAKEMAASGVPPDQRTLETLILVCLDSGNQSSAEKYLADLEAQGW 475
                 4678888899998866588889999*************************************9999888899988888777777777665 PP

>> PPR  PPR repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0      0.05   1.1e+02      12      31 .]      94     113 ..      93     113 .. 0.92
   2 !    9.5   0.0   0.00054       1.2       3      31 .]     155     183 ..     155     183 .. 0.92
   3 ?    0.8   0.0      0.33   7.5e+02       5      24 ..     192     211 ..     189     212 .. 0.87
   4 ?   -1.8   0.0       2.3   5.2e+03      12      24 ..     270     282 ..     269     285 .. 0.86
   5 !    8.7   0.0     0.001       2.2       4      31 .]     297     324 ..     295     324 .. 0.90
   6 ?    3.9   0.0     0.035        78       2      30 ..     411     439 ..     410     440 .. 0.86

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.05
         PPR  12 knGkleeAlelfkeMkekGi 31 
                 ++G ++ +  l++eM e Gi
  EEA22584.1  94 QHGSVKNVRNLLREMAEQGI 113
                 689999**********9997 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00054
         PPR   3 ynslIsgycknGkleeAlelfkeMkekGi 31 
                 +  ++ g+ ++++le Al+ +++M++kGi
  EEA22584.1 155 WHHVVAGLLRENQLELALDRLEQMERKGI 183
                 566889**********************7 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.33
         PPR   5 slIsgycknGkleeAlelfk 24 
                  lI  +c   +++eAl+l++
  EEA22584.1 192 LLIYKLCDVDEFSEALRLIR 211
                 689999**********9975 PP

  == domain 4  score: -1.8 bits;  conditional E-value: 2.3
         PPR  12 knGkleeAlelfk 24 
                  +G++  A+ +f+
  EEA22584.1 270 EHGDVILAEAVFR 282
                 589********97 PP

  == domain 5  score: 8.7 bits;  conditional E-value: 0.001
         PPR   4 nslIsgycknGkleeAlelfkeMkekGi 31 
                   l+++y++n +++ A+e+  +M ++++
  EEA22584.1 297 GKLVQVYARNADIKSAFEIVYQMHKHNV 324
                 56899*******************9875 PP

  == domain 6  score: 3.9 bits;  conditional E-value: 0.035
         PPR   2 tynslIsgycknGkleeAlelfkeMkekG 30 
                 t+n lIs + +  +++ +  + keM  +G
  EEA22584.1 411 TFNNLISLCHQTSRPDICTFFAKEMAASG 439
                 9**********999999888888887777 PP

>> PPR_3  Pentatricopeptide repeat domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       4.1   9.2e+03      40      54 ..      70      84 ..      59      88 .. 0.71
   2 ?    5.0   0.0     0.012        26       2      41 ..     104     143 ..     103     152 .. 0.90
   3 ?   -0.4   0.0      0.54   1.2e+03      20      46 ..     157     183 ..     148     184 .. 0.80
   4 ?   -2.7   0.0       2.9   6.4e+03      20      38 ..     227     245 ..     221     247 .. 0.80
   5 !   11.3   0.0   0.00012      0.27      16      46 ..     294     324 ..     280     330 .. 0.89
   6 ?    1.7   0.1      0.13   2.8e+02      49      60 ..     408     419 ..     407     422 .. 0.87
   7 !    6.2   0.0    0.0049        11       4      42 ..     433     471 ..     431     476 .. 0.90

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 4.1
       PPR_3 40 rmkkkgikPtvvtyN 54
                 ++  +++Pt   y 
  EEA22584.1 70 LLQRHRVTPTTRHYK 84
                456778999987775 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.012
       PPR_3   2 ilremerkgikldvvtYthLLtayanagnkklalevlerm 41 
                 +lrem ++gi  d  t  + L++ a+  ++ l  ev+e +
  EEA22584.1 104 LLREMAEQGITADSATLHAALEVLAVHPDYLLRQEVIEAL 143
                 89*********************99999999888888766 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 0.54
       PPR_3  20 hLLtayanagnkklalevlermkkkgi 46 
                 h   +  +   ++lal  le+m+ kgi
  EEA22584.1 157 HVVAGLLRENQLELALDRLEQMERKGI 183
                 666666777888999999999999998 PP

  == domain 4  score: -2.7 bits;  conditional E-value: 2.9
       PPR_3  20 hLLtayanagnkklalevl 38 
                  LL+a+++   ++ +++v 
  EEA22584.1 227 YLLRAAMKRSHYETVEYVW 245
                 6999999999999888885 PP

  == domain 5  score: 11.3 bits;  conditional E-value: 0.00012
       PPR_3  16 vtYthLLtayanagnkklalevlermkkkgi 46 
                 ++Y  L ++ya++ + k a+e++ +m k  +
  EEA22584.1 294 YDYGKLVQVYARNADIKSAFEIVYQMHKHNV 324
                 89************************99764 PP

  == domain 6  score: 1.7 bits;  conditional E-value: 0.13
       PPR_3  49 tvvtyNailgvi 60 
                 + +t+N +++++
  EEA22584.1 408 NTDTFNNLISLC 419
                 679******999 PP

  == domain 7  score: 6.2 bits;  conditional E-value: 0.0049
       PPR_3   4 remerkgikldvvtYthLLtayanagnkklalevlermk 42 
                 +em + g+ +d  t  +L+ ++   gn+  a++ l+ ++
  EEA22584.1 433 KEMAASGVPPDQRTLETLILVCLDSGNQSSAEKYLADLE 471
                 699****************************99887766 PP

>> PET122  PET122
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       1.3   2.9e+03      22      47 ..      67      92 ..      46     105 .. 0.61
   2 ?   13.7   0.2   1.3e-05     0.028      13      65 ..     194     248 ..     187     252 .. 0.84
   3 ?   -1.9   0.0      0.73   1.6e+03     164     205 ..     294     338 ..     275     343 .. 0.70
   4 ?   -2.7   0.0       1.3     3e+03     211     246 ..     386     421 ..     372     424 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1.3
      PET122 22 fdevLkeiRkiplkeldysflqlyLs 47
                + e+L++ R +p+++  +++l + + 
  EEA22584.1 67 LKELLQRHRVTPTTRHYKAYLLTNID 92
                34556666666666666665555554 PP

  == domain 2  score: 13.7 bits;  conditional E-value: 1.3e-05
      PET122  13 lyldclnrkfdevLkeiRkiplkeldy.sflqlyLsrs.vqwghvasvdyiWsky 65 
                 +y+ c   +f+e+L+ iR+ p k  ++ s + lyL r+ ++ +h + v+y+W+  
  EEA22584.1 194 IYKLCDVDEFSEALRLIRSRPNKAKSVsSAMWLYLLRAaMKRSHYETVEYVWKNA 248
                 678888899************987775257899998862688**********975 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 0.73
      PET122 164 rDfPyLtks.vgkedrdllqellfeen..kltiknrstltLLLnl 205
                  D+  L +  + ++d + + e++++ +  +++ik ++t ++L  +
  EEA22584.1 294 YDYGKLVQVyARNADIKSAFEIVYQMHkhNVPIKPETTRPILQSM 338
                 577777777677777777777776544226888999999888665 PP

  == domain 4  score: -2.7 bits;  conditional E-value: 1.3
      PET122 211 elsldfkirlFekflesyksldyddslaiLlrklke 246
                 + +++  +++++ +++   s + +d+   L+  +++
  EEA22584.1 386 SRAIEVAVSIYKDLFDICASGANTDTFNNLISLCHQ 421
                 457889999999999999999999999999988876 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   0.4    0.0015       3.3      18      57 ..     102     145 ..      85     167 .. 0.67
   2 ?   -3.5   0.0       6.6   1.5e+04      29      46 ..     328     346 ..     314     350 .. 0.65
   3 ?    2.9   0.0     0.066   1.5e+02      28      72 ..     407     452 ..     383     468 .. 0.80

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.0015
      HEAT_2  18 raairaLg....rignpealpaLvellededpavRraaaeaLga 57 
                 r+ +r+++    + ++ ++ +aL  l+ ++d   R++++eaL a
  EEA22584.1 102 RNLLREMAeqgiTADSATLHAALEVLAVHPDYLLRQEVIEALRA 145
                 56666666332223333445555556689999999999999864 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 6.6
      HEAT_2  29 npealpaLvell.ededpa 46 
                 +++++p+L ++  e++dpa
  EEA22584.1 328 PETTRPILQSMEtESSDPA 346
                 4455555555554555665 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.066
      HEAT_2  28 gnpealpaLvell.ededpavRraaaeaLgaigdpealpaLkelld 72 
                 +n+++++ L++l+ +++ p++    a+ ++a g p + + L+ l +
  EEA22584.1 407 ANTDTFNNLISLChQTSRPDICTFFAKEMAASGVPPDQRTLETLIL 452
                 68899********88999**************97666666665554 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0       2.7     6e+03      13      38 ..      94     121 ..      84     132 .. 0.63
   2 ?   -0.4   0.1       1.3   2.9e+03       4      29 ..     155     180 ..     152     182 .. 0.77
   3 ?   -1.4   0.0       2.7     6e+03      36      41 ..     223     228 ..     199     250 .. 0.60
   4 ?    2.0   0.0      0.23   5.1e+02       6      29 ..     298     321 ..     295     329 .. 0.85
   5 ?    5.1   0.0     0.022        48       7      33 ..     450     476 ..     445     482 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 2.7
      TPR_14  13 alGdpdeAiallrralala..Pddaeaw 38 
                 + G  +  ++llr++ +++   d+a+++
  EEA22584.1  94 QHGSVKNVRNLLREMAEQGitADSATLH 121
                 5566666777888887764224444433 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 1.3
      TPR_14   4 llalaeallalGdpdeAiallrrala 29 
                 +   ++ ll+  +++ A++ l+++ +
  EEA22584.1 155 WHHVVAGLLRENQLELALDRLEQMER 180
                 66667789999999999999998866 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 2.7
      TPR_14  36 eawlll 41 
                 + wl+l
  EEA22584.1 223 AMWLYL 228
                 333333 PP

  == domain 4  score: 2.0 bits;  conditional E-value: 0.23
      TPR_14   6 alaeallalGdpdeAiallrrala 29 
                 +l+++++++ d + A ++  ++ +
  EEA22584.1 298 KLVQVYARNADIKSAFEIVYQMHK 321
                 699************998877766 PP

  == domain 5  score: 5.1 bits;  conditional E-value: 0.022
      TPR_14   7 laeallalGdpdeAiallrralalaPd 33 
                 l  ++l +G+   A+++l ++ a++++
  EEA22584.1 450 LILVCLDSGNQSSAEKYLADLEAQGWE 476
                 778999***************999875 PP

>> ECSIT  Evolutionarily conserved signalling intermediate in Toll pathway
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0    0.0087        19      54      94 ..      86     127 ..      50     143 .. 0.82
   2 ?    4.0   0.0      0.01        23     115     142 ..     167     194 ..     162     197 .. 0.86
   3 ?   -1.1   0.0      0.37   8.3e+02      84     142 ..     393     451 ..     382     466 .. 0.66

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.0087
       ECSIT  54 fekrsv.rrrghveFiyaAlkkmeefgverDlevYkalldvf 94 
                 +   ++ r++g v+ + + l++m e g++ D ++ +a l+v+
  EEA22584.1  86 YLLTNIdRQHGSVKNVRNLLREMAEQGITADSATLHAALEVL 127
                 455566467899*******************99988888776 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.01
       ECSIT 115 qqecgvdvLeqmeengvlPdketeallv 142
                 q e ++d Leqme++g+l ++ +++ll+
  EEA22584.1 167 QLELALDRLEQMERKGILIEQWLHSLLI 194
                 66788999**********9998888887 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 0.37
       ECSIT  84 levYkalldvfPkevfiprnllqaeFlhyprqqecgvdvLeqmeengvlPdketeallv 142
                 +++Yk l+d+   +  + +        h   + ++ +   ++m   gv Pd+ t   l+
  EEA22584.1 393 VSIYKDLFDICASGANTDTFNNLISLCHQTSRPDICTFFAKEMAASGVPPDQRTLETLI 451
                 67777777777776655444444455666666666667777888888888877644333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (490 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       694  (0.0387082); expected 358.6 (0.02)
Passed bias filter:                      552  (0.0307881); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.44
# Mc/sec: 3344.55
//
Query:       EEA22585.1  [L=170]
Description: U6 snRNA-associated Sm-like protein LSM4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.5e-17   63.0   0.0    2.2e-17   62.5   0.0    1.3  1  LSM              LSM domain
  ------ inclusion threshold ------
      0.011   15.8   0.0      0.016   15.4   0.0    1.3  1  SM-ATX           Ataxin 2 SM domain


Domain annotation for each model (and alignments):
>> LSM  LSM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.5   0.0   2.5e-21   2.2e-17       3      66 ..      59     122 ..      57     123 .. 0.95

  Alignments for each domain:
  == domain 1  score: 62.5 bits;  conditional E-value: 2.5e-21
                 HHHTTTSEEEEEETTSEEEEEEEEEEETTSEEEEEEEEEEETTETEEEEEEEEEEEGGGEEEEE CS
         LSM   3 lkklinkkvtvelkngrelrGtLkgfDqfmNlvLedveetlkdkkekrklglvliRGnnivlis 66 
                 l   +++ ++velkng++l G L+++D++mNl L++v+ t +++++  +l +v++RGnni ++ 
  EEA22585.1  59 LTAAQGHPMLVELKNGETLNGHLVNCDNWMNLTLKEVVQTTPEGDRFFRLPEVYVRGNNIKYLR 122
                 77889********************************************************985 PP

>> SM-ATX  Ataxin 2 SM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.4   0.0   1.7e-06     0.016       7      51 ..      58     100 ..      56     140 .. 0.90

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 1.7e-06
                 HHHTTTTSEEEEEETTS-EEEEEEEEE-T..T--EEEEEEEETTS CS
      SM-ATX   7 lltslvGkevevtvknGevyeGifstvslekdfsvvLkmarkvkk 51 
                 llt+  G++  v++knGe+  G +  ++    ++++Lk + ++++
  EEA22585.1  58 LLTAAQGHPMLVELKNGETLNGHLVNCDN--WMNLTLKEVVQTTP 100
                 7999********************99999..*******9999988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (170 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       284  (0.0158403); expected 358.6 (0.02)
Passed bias filter:                      237  (0.0132188); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.43
# Mc/sec: 1177.90
//
Query:       EEA22586.1  [L=769]
Description: hypothetical protein PMAA_092110 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.016   15.2   0.2      0.058   13.3   0.0    1.9  2  APH              Phosphotransferase enzyme family
       0.19   10.9   0.0       0.32   10.2   0.0    1.3  1  Fructosamin_kin  Fructosamine kinase


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   6.5e-06     0.058      42     115 ..      56     131 ..      40     192 .. 0.86
   2 ?   -2.0   0.6       0.3   2.7e+03     108     148 ..     544     585 ..     530     602 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 6.5e-06
                 HHHHHHHHTT-.B--B-CTTBS-EEETTEEEEEEE----EE-SS...HHHHHHHHHHHHHHHHHHCCHHCH..-STTTB CS
         APH  42 allrlLakagv.pvPevlagdtddeeigllfalieyvpgrsllr...klsaaqlpellealgeflaalhqvd.paalpl 115
                    ++L+++   pvP+vl      +++++ + ++e++ g ++ +   k s++ + +ll +lg +++++ +++ p+  ++
  EEA22586.1  56 STIHFLSQNTSlPVPRVLC---AFTHSERSYIVMERIKGDIIGNgwvKRSEESKAKLLSQLGKLIREMRDLPpPRGVGV 131
                 556777855445******9...8899999999***************************************85555555 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.3
                 H.-STTTB-SHHCHTCCHHHHHHCHHHCCCGCCTCC.HHHHH CS
         APH 108 vdpaalpladflaqdlellrqlesatarllaselld.lleel 148
                 +++a+++ +++ a+++e+lr + +++++ +++++++ ++ ++
  EEA22586.1 544 HSTAFRRRRRDIASRREELRTRRAYRNAARRLRWRQwWQGRF 585
                 445667777777777777777777777777777777655555 PP

>> Fructosamin_kin  Fructosamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   3.6e-05      0.32      54      97 ..      49      92 ..      22     122 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 3.6e-05
  Fructosamin_kin 54 emFeaEaesLealaetqtirvPkvlavGelkdasfLvleyLelk 97
                      ++ +Ea  ++ l++ +++ vP+vl++ +++++s++v+e ++ +
       EEA22586.1 49 RVHLSEASTIHFLSQNTSLPVPRVLCAFTHSERSYIVMERIKGD 92
                     56778**********************************98754 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (769 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       813  (0.0453455); expected 358.6 (0.02)
Passed bias filter:                      577  (0.0321825); expected 358.6 (0.02)
Passed Vit filter:                        67  (0.00373696); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.72u 0.29s 00:00:01.01 Elapsed: 00:00:00.44
# Mc/sec: 5194.88
//
Query:       EEA22587.1  [L=511]
Description: histone acetyltransferase type b catalytic subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.9e-53  178.7   0.1    1.7e-52  177.9   0.1    1.4  1  Hat1_N           Histone acetyl transferase HAT1 N-terminus
  ------ inclusion threshold ------
      0.061   13.3   0.0       0.14   12.1   0.0    1.6  1  Acetyltransf_10  Acetyltransferase (GNAT) domain
       0.11   12.9   0.0       0.27   11.7   0.0    1.6  1  Acetyltransf_7   Acetyltransferase (GNAT) domain


Domain annotation for each model (and alignments):
>> Hat1_N  Histone acetyl transferase HAT1 N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  177.9   0.1   2.8e-56   1.7e-52       1     160 []       7     165 ..       7     165 .. 0.96

  Alignments for each domain:
  == domain 1  score: 177.9 bits;  conditional E-value: 2.8e-56
                 GEEEHHHHEEEEEESSS.EEE.........E--S--HHHHTTTTEEESEES-EEEEEEETTT--EEEEEE-SEE--.STTS-..-HHHHHHTTS-T..E CS
      Hat1_N   1 wtvdanealkiklvrseedleeeektksesfhPeftyqiFgeeetIfGYkdLkInlyfaagslkpylkvsyseklkdkskte.kdvekklkeflpeeaf 98 
                 wt+dan+a++++l+++ e+      t++e fhP+fty+iFg+ee+IfGYk+L I+l+fa ++l++++++sy+ek+k+ ++++ +d++k+l+e++ e+af
  EEA22587.1   7 WTCDANDAVQLTLIKPGEQK----PTTAEIFHPQFTYPIFGDEEQIFGYKGLIIRLRFATHDLRTHVHISYDEKFKAVGDAAaVDLNKTLREWVSESAF 101
                 9***************7773....567778*************************************************99978*************** PP

                 S-HHHHHHHHH..HHH.H--GGSEEEEEETTEE..EEEEEEESSSHHHHHHHHHHTHHHHHHST CS
      Hat1_N  99 kskeeFekale..ekaksfkppGelihsytrekkefeiykasladpavrelhrrlqifvllFIE 160
                 ++++++e++++  +kak+f+ppG+l+hsy+++++++ei+++slad++v +l+ r q+f+++FIE
  EEA22587.1 102 TKLSDYENSVQndSKAKDFTPPGKLVHSYKSKNRNYEIWAGSLADDDVHNLLGRAQVFIPFFIE 165
                 ***********88889****************999****************************9 PP

>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   2.3e-05      0.14      49      95 ..     241     287 ..     237     313 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 2.3e-05
  Acetyltransf_10  49 rdgshisllfVdpeyrgqGigkaLleaveeeaekdgikleltvnasp 95 
                       ++s+i+ + + p ++g G g++L + + + +  d+  +eltv+  +
       EEA22587.1 241 PSRSRIAQFLILPPHQGSGHGSQLYNIIHKDCIADKTVVELTVEDPN 287
                      56789***************************888766699998655 PP

>> Acetyltransf_7  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   4.6e-05      0.27      26      55 ..     245     277 ..     213     304 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 4.6e-05
                     CTEEEEE-GGGTTSSHHHHHHHHTTSEEE...E CS
  Acetyltransf_7  26 eitrlaVdpeyrgkGiGraLleaaekgii...l 55 
                      i  + ++p ++g G G++L ++++k +i   +
      EEA22587.1 245 RIAQFLILPPHQGSGHGSQLYNIIHKDCIadkT 277
                     455688****************74455653321 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (511 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       709  (0.0395449); expected 358.6 (0.02)
Passed bias filter:                      556  (0.0310112); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.26s 00:00:00.86 Elapsed: 00:00:00.44
# Mc/sec: 3516.84
//
Query:       EEA22588.1  [L=576]
Description: hypothetical protein PMAA_092130 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.9e-06   25.9   0.0    2.8e-05   24.3   0.0    1.9  1  Retrotrans_gag  Retrotransposon gag protein
  ------ inclusion threshold ------
      0.043   13.7   0.0       0.11   12.4   0.0    1.6  1  DUF4939         Domain of unknown function (DUF4939)


Domain annotation for each model (and alignments):
>> Retrotrans_gag  Retrotransposon gag protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.3   0.0   3.1e-09   2.8e-05      21      95 ..     108     181 ..      89     182 .. 0.89

  Alignments for each domain:
  == domain 1  score: 24.3 bits;  conditional E-value: 3.1e-09
  Retrotrans_gag  21 rsidasesWkdlkkaflktflpserkdqleeelsslrQ.gtesvreYvtrfktladqlde.vlteeakiekflaGLn 95 
                     ++++    ++++ +++ + + ++++++++e++l  l+Q  te v  +v++f++++ +++   +++  ki+ f++ Ln
      EEA22588.1 108 TNTW---DYNTILDQLARVYDNPNKTNEAEDRLYALKQgSTEAVPAFVAKFERILYEARGqDWPDVNKISVFRNSLN 181
                     3333...67899999**********************************************************9998 PP

>> DUF4939  Domain of unknown function (DUF4939)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   1.2e-05      0.11      11     105 ..      30     125 ..      19     134 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 1.2e-05
     DUF4939  11 lalprlrqkrrwrnpipfpetfdGdtdrlpefivqtlsymlvdektfssdalkvtflitrltGealewvlpyi.kkdspllndyraflaemkrvfG 105
                 ++ + +    r+++ +p pe+f G +++   ++  + + + vd +   +   +  ++   l  + +  vlp + + +s    dy++ l+++ rv+ 
  EEA22588.1  30 IQSAARATSSRPKAVLPDPEKFAGSAQKYDTWLPSIKAKLRVDADAIGNAIAQFYYVYLNLDSHVQAMVLPQLsEAESTNTWDYNTILDQLARVYD 125
                 33445567899************************************************************99346899999****9999998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (576 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       551  (0.0307323); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.45
# Mc/sec: 3808.72
//
Query:       EEA22589.1  [L=411]
Description: benzoate 4-monooxygenase cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.1e-42  144.2   0.0    7.7e-42  143.6   0.0    1.2  1  p450      Cytochrome P450
  ------ inclusion threshold ------
      0.015   14.7   0.1      0.051   13.0   0.0    1.7  2  DUF1204   Protein of unknown function (DUF1204)
       0.18   10.9   0.1       0.26   10.4   0.1    1.2  1  CyRPA     Cysteine-Rich Protective Antigen 6 bladed domain


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  143.6   0.0   1.3e-45   7.7e-42      84     405 ..      18     344 ..       8     346 .. 0.83

  Alignments for each domain:
  == domain 1  score: 143.6 bits;  conditional E-value: 1.3e-45
                 TSSSTTCGH.HHHHHHHHHHHHHHTSHSTT.THHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHH.HHHHH CS
        p450  84 gkgvlfang.ekwkklRrfltptltsfgkl.sleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledeklselv.kavee 179
                 ++  +fa+  +  +  R  +++ + +  ++ sle+lv+e  ++l+ +++++ ++ ++l++   +s  + dvi+++l+g++fd l++++++  v +a+  
  EEA22589.1  18 HEKYVFASThKNSRARRGYMNKYFSKR-NMsSLEPLVQERLDRLCSRIDERLKTGETLNLDGCFSALTGDVITRLLYGNNFDYLGSPDFQFVVrNAFMG 115
                 444555555156666666666666666.888***************************************************99999875544134444 PP

                 HHHHHHCHHHHCCCCCHHHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHC...SCSSCSHHHHHHHHCTTCTCT.SSSSHHHHHHHHHHHHHHH CS
        p450 180 lssllskssvqllllfpllkylptkllrklkeavkklkdlldklieerretldsa...kksrrdfldalllakkekkge.sklsdeelaatvlellfaG 274
                  s++ +  +  + l  ++lk +p +  + +   v +l++l  ++ e+ ++++  +    +++++ +   l++   ++ + ++ + + l+ + +++l+aG
  EEA22589.1 116 FSKMYHLAR-FIPLAVKILKLMPLPVIQLIAPPVAELQQLRAEIAENGYKKFHADkwdVEEKKSVIVSSLND---ESIPpAERTVDRLVDEGTVILLAG 210
                 444553333.3555555799***********************************66644566666666666...4666689***************** PP

                 HHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHCCTTT..T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEETT.EEE-TT-EEEEEHHHH CS
        p450 275 vdTtsstlswaLyeLaknPevqeklreEidevlgdkr..eptyddlqklpyldavikEtLRlhpvvplllpRevtkdvvirg.ylipkGtevivnlyal 370
                 +dTts  l+ ++y+L+ nP+  + +r+E+++ l  ++    +  +l+klpyl+ vi+E +Rl+   ++++pR  t+d    +  +ip G +v++++  +
  EEA22589.1 211 TDTTSRSLAVTMYYLLSNPDCLAWMRHELETSLSFNKdhVYDLGQLEKLPYLTGVIHEGFRLSFGPVSRMPRISTQDSLQYNeWSIPPGATVSMSTMFM 309
                 *********************************66665689999*******************98888********8766666**************** PP

                 HT-TTTSSSTTS--GGGGB-TTSCTESSCTT--TT CS
        p450 371 hrdpevfpnPeeFdpeRFldekgnskrksfaflPF 405
                 h d++++pnP ++dpeR+ +++++      +  +F
  EEA22589.1 310 HLDENIYPNPTKYDPERWIRATKQGINLTKYLTAF 344
                 *******************9999554445555556 PP

>> DUF1204  Protein of unknown function (DUF1204)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   8.6e-06     0.051      46     106 ..      15      70 ..       7      89 .. 0.85
   2 ?   -1.3   0.0       0.2   1.2e+03     144     184 ..     148     191 ..     141     201 .. 0.74

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 8.6e-06
     DUF1204  46 kkekektveledrlksekkrlrerrekyaefvrrkalikvaelvqkrldrvkahlddkkki 106
                 +k++ek+v       s +k  r rr    ++  ++ +  +  lvq+rldr+ + +d+++k 
  EEA22589.1  15 EKMHEKYV-----FASTHKNSRARRGYMNKYFSKRNMSSLEPLVQERLDRLCSRIDERLKT 70 
                 56666665.....46888999****999999999***********************9986 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.2
     DUF1204 144 vadaeelkaevkafeiteledddfdv...rtlfeklleeerveP 184
                 va+ ++l+ae+   +  ++  d +dv   +++    l++e ++P
  EEA22589.1 148 VAELQQLRAEIAENGYKKFHADKWDVeekKSVIVSSLNDESIPP 191
                 88999999999999999999999999332345555566666666 PP

>> CyRPA  Cysteine-Rich Protective Antigen 6 bladed domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.1   4.4e-05      0.26     234     283 ..       3      55 ..       1      64 [. 0.77

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 4.4e-05
       CyRPA 234 nlikedkslqditklngyYitslskkd.kfeecyl..yyteknaivvklevqk 283
                 ++ik+ ++l++i k++++Y+ + ++k+ ++ + y+  y+ ++n  ++++ vq+
  EEA22589.1   3 DVIKDGRYLWQIEKMHEKYVFASTHKNsRARRGYMnkYFSKRNMSSLEPLVQE 55 
                 78******************776665515566665559999998888887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (411 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       553  (0.0308439); expected 358.6 (0.02)
Passed bias filter:                      529  (0.0295053); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.30s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 2724.72
//
Query:       EEA22590.1  [L=403]
Description: ZIP metal ion transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-34  119.1  16.4    4.5e-26   91.9   9.3    3.0  2  Zip       ZIP Zinc transporter
  ------ inclusion threshold ------
      0.036   13.5   6.2      0.029   13.8   1.7    2.3  3  SfLAP     Sap, sulfolipid-1-addressing protein


Domain annotation for each model (and alignments):
>> Zip  ZIP Zinc transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.6   7.3e-10   6.6e-06       5      70 ..       8      68 ..       4      84 .. 0.89
   2 !   91.9   9.3     5e-30   4.5e-26      75     332 ..     154     397 ..     138     398 .. 0.68

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 7.3e-10
         Zip  5 ilaiiaililsllgllgpllvpkiskllsklllslllafavGvllgtaflhLlPealealeesqle 70
                ++++i++ ++s+l + +pl +      ls +  ++++ +++G+l+gta++ ++Pe++e l++sq+ 
  EEA22590.1  8 LTLSIVMAVTSFLIGALPLSFT-----LSTSQSRFISSLGMGILVGTALVIIIPEGVETLYSSQNY 68
                688999*************998.....7778899****************************9975 PP

  == domain 2  score: 91.9 bits;  conditional E-value: 5e-30
         Zip  75 h....plagllvllGflllllveklltmivekksshkektpkkasssssesaakksvsndkveeseekedhvaeadtdadskeelrngkqeksesekeq 169
                 +     + g+ ++ Gf+l+++++kl + +                                                                      
  EEA22590.1 154 IsalhAWIGISLISGFILMYIIDKLPSFA---------------------------------------------------------------------- 182
                 02233455555555555555555544444...................................................................... PP

         Zip 170 as................................eeedkeklaslkvraiilllglilHsfidGLAlG.vssssstgislfiAvllHelpeelglgaiL 235
                  s                                  +++ +  +++  ++ ++ gl++H   dG+AlG   s+ss  +++f+A+l+H++p+++gl+++L
  EEA22590.1 183 -SppkarrlpyhisldnlggsglrrssspnrdggLLDQDNNNNNQNPHSFAMTTGLVIHAAADGIALGvSGSNSSLSFIIFLALLVHKAPAAFGLTSVL 280
                 .044444444444444444444444444444444344455556778889*******************55577778899******************** PP

         Zip 236 lkaglsrkkavllnllfaltaplGiliGilvrs......isessgaeivsgillalsaGtflYvalvell...phEllnek................gs 309
                 lk gls++ a  + l+f+l+ap+G+l ++ + +       s +  + + +g+ll +saGtflYva+  +    p     ++                ++
  EEA22590.1 281 LKQGLSSRVAGRHLLVFSLAAPVGALMTFIIVHtlgsgfGSDEASNRWRTGVLLLFSAGTFLYVAMHTIQdiaP-----SSspspshshsngyadsrET 374
                 ********************************999999888899999******************987653332.....33223333335567766644 PP

         Zip 310 sslkqsllqllglllGfalmlll 332
                  + k s+  l++ ++G++l+l+l
  EEA22590.1 375 PKPKGSIQDLAVSVVGMILPLFL 397
                 55666777777777777776665 PP

>> SfLAP  Sap, sulfolipid-1-addressing protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.1     0.019   1.7e+02      39      81 ..       7      53 ..       4      97 .. 0.72
   2 ?   -3.8   0.0       0.8   7.1e+03      37      60 ..     159     182 ..     155     187 .. 0.65
   3 ?   13.8   1.7   3.3e-06     0.029       2      93 ..     261     359 ..     260     399 .. 0.70

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.019
       SfLAP 39 lvvlvalglivlfvlrslls..gasaapssaikalq..ivlGvllll 81
                l++l +++++  f+ ++l+    +s+++s++i+ l   i++G +l++
  EEA22590.1  7 LLTLSIVMAVTSFLIGALPLsfTLSTSQSRFISSLGmgILVGTALVI 53
                67778888888888888887554444466666655311445555554 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 0.8
       SfLAP  37 gwlvvlvalglivlfvlrsllsga 60 
                 +w+   ++ g+i++ + ++l+s+a
  EEA22590.1 159 AWIGISLISGFILMYIIDKLPSFA 182
                 566666666777777777776655 PP

  == domain 3  score: 13.8 bits;  conditional E-value: 3.3e-06
       SfLAP   2 lvlAlvvalsPlrlgvavlllsr....prpvlnllaFlvgwlvvlvalglivlfvlrsllsgasaapssaikalqivlGvlllllaaveavrr.....p 91 
                 + lAl+v   P   g++ +ll++    + + ++ll+F +++ v+++++++iv +++++++s+   a  ++ + + ++  ++  l+ a+++ +       
  EEA22590.1 261 IFLALLVHKAPAAFGLTSVLLKQglssRVAGRHLLVFSLAAPVGALMTFIIVHTLGSGFGSDE--ASNRWRTGVLLLFSAGTFLYVAMHTIQDiapssS 357
                 6799999999999999999987666658899*****************************544..5678887777776665555444444444355443 PP

       SfLAP  92 ka 93 
                 ++
  EEA22590.1 358 PS 359
                 33 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (403 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       579  (0.032294); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.47
# Mc/sec: 2552.93
//
Query:       EEA22591.1  [L=717]
Description: F-box and WD repeat-containing protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.5e-39  133.3  22.5    2.7e-07   31.2   0.1    7.9  8  WD40            WD domain, G-beta repeat
    6.1e-12   45.3   0.2    1.2e-11   44.2   0.2    1.6  1  F-box-like      F-box-like
    7.4e-09   35.8   0.5       0.65   10.3   0.0    6.1  6  ANAPC4_WD40     Anaphase-promoting complex subunit 4 WD40 dom
    7.6e-08   31.4   7.0      0.093   11.4   0.1    6.1  7  Nup160          Nucleoporin Nup120/160
      3e-05   23.8   0.4    6.4e-05   22.7   0.4    1.6  1  F-box           F-box domain
    0.00067   19.2   0.1     0.0012   18.4   0.1    1.4  1  F-box_5         F-box
     0.0024   17.5   2.4       0.02   14.5   0.9    2.5  2  PQQ_2           PQQ-like domain
     0.0033   16.4   5.0        2.9    6.7   0.0    4.1  4  PALB2_WD40      Partner and localizer of BRCA2 WD40 domain
     0.0037   16.6   0.0       0.21   10.8   0.0    2.6  3  WD40_like       WD40-like domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       4.7   9.3e+03      12      38 .]     341     369 ..     333     369 .. 0.57
   2 !   17.8   0.1   2.2e-06    0.0044       3      38 .]     374     408 ..     372     408 .. 0.82
   3 !   28.5   0.3   9.1e-10   1.8e-06       1      38 []     412     449 ..     412     449 .. 0.89
   4 !   22.2   0.8     9e-08   0.00018       1      38 []     453     489 ..     453     489 .. 0.92
   5 !   31.2   0.1   1.3e-10   2.7e-07       1      38 []     493     529 ..     493     529 .. 0.92
   6 !   18.0   0.3     2e-06    0.0039       1      38 []     533     569 ..     533     569 .. 0.81
   7 !   24.8   0.1   1.4e-08   2.7e-05       3      38 .]     575     609 ..     573     609 .. 0.90
   8 ?    0.1   0.0      0.88   1.8e+03       1      34 [.     613     647 ..     613     648 .. 0.78

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 4.7
                 S....EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  12 s....vtslafspdgawlasGsdDgtvriWd 38 
                 +    vtsl  +  +++++ + d+ +++++d
  EEA22591.1 341 PdqgvVTSL--HLTSKYIVVALDNAKIHVYD 369
                 334556888..55555566565566666665 PP

  == domain 2  score: 17.8 bits;  conditional E-value: 2.2e-06
                 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +++tl+GH  +v+++   p  ++l+sG+ D+ vr+W+
  EEA22591.1 374 NQKTLEGHvMGVWAM--VPWDDLLVSGGCDREVRVWN 408
                 799*****7778877..66667799**88*******8 PP

  == domain 3  score: 28.5 bits;  conditional E-value: 9.1e-10
                 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 g c++ l+GH s v++l+ s+ ++ + sGs+D t+riWd
  EEA22591.1 412 GACTHLLRGHtSTVRCLKMSDKNTAI-SGSRDTTLRIWD 449
                 5799******777****988888886.8**********9 PP

  == domain 4  score: 22.2 bits;  conditional E-value: 9e-08
                 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 g+c ++l GH  sv++l    +g++++sGs+D t riW+
  EEA22591.1 453 GNCRGVLVGHqASVRCL--GIHGDLVVSGSYDTTARIWS 489
                 6899******988**99..889999*************5 PP

  == domain 5  score: 31.2 bits;  conditional E-value: 1.3e-10
                 TEEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   1 gqclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 g+clrtl+GH s ++++    dg+ +a+Gs D +vriWd
  EEA22591.1 493 GRCLRTLSGHfSQIYAI--AFDGRRIATGSLDTSVRIWD 529
                 68********777****..559999*************9 PP

  == domain 6  score: 18.0 bits;  conditional E-value: 2e-06
                 TEEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   1 gqclrtltGHss.vtslafspdgawlasGsdDgtvriWd 38 
                 gqc  +l GH+s v  l  +  g+ l++G+ Dg+vr+W+
  EEA22591.1 533 GQCHAILQGHTSlVGQL--QMRGDTLVTGGSDGSVRVWS 569
                 689999****6657666..667777999988*******5 PP

  == domain 7  score: 24.8 bits;  conditional E-value: 1.4e-08
                 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +++ l +H +svtsl  + d++ ++sG+ Dg v++Wd
  EEA22591.1 575 PIHRLAAHdNSVTSL--QFDSTRIVSGGSDGRVKVWD 609
                 789999**999****..77888899*988*******9 PP

  == domain 8  score: 0.1 bits;  conditional E-value: 0.88
                 TEEEEEEESS.SSEEEEEEETTSSEEEEE.ETTSEE CS
        WD40   1 gqclrtltGH.ssvtslafspdgawlasG.sdDgtv 34 
                 gq+lr+l++    v+ +af  ++a ++++ s  +tv
  EEA22591.1 613 GQLLRELSTPaEAVWRVAFEEEKAVIMASrS-GRTV 647
                 6889999988666******999999997744.6665 PP

>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.2   0.2   6.3e-15   1.2e-11       5      47 ..     183     225 ..     179     226 .. 0.94

  Alignments for each domain:
  == domain 1  score: 44.2 bits;  conditional E-value: 6.3e-15
  F-box-like   5 PdEiLlqIFsyL.ppsdLlrlalVCrrWrrvaldtplLWrrlvl 47 
                 P+Ei+l+++s++ +p++L+r+++V++rW+++++d+   W++l+ 
  EEA22591.1 183 PNEICLRVLSFVdDPKTLARASQVSKRWHELINDD-ITWKHLCD 225
                 ************8899*******************.******95 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0      0.37   7.3e+02      48      71 ..     351     374 ..     331     391 .. 0.82
   2 ?    4.0   0.0     0.031        61      50      89 ..     392     430 ..     384     433 .. 0.88
   3 ?    3.1   0.0     0.059   1.2e+02      37      81 ..     462     504 ..     438     512 .. 0.75
   4 ?    3.8   0.0     0.037        73      48      76 ..     511     539 ..     484     550 .. 0.77
   5 !   10.3   0.0   0.00033      0.65      47      90 ..     550     592 ..     540     594 .. 0.90
   6 !    6.3   0.0     0.006        12      49      89 ..     592     631 ..     590     634 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.37
  ANAPC4_WD40  48 pdgklLavaysdgevrlldaesgk 71 
                     k ++va ++ +++++d + g+
   EEA22591.1 351 LTSKYIVVALDNAKIHVYDTNGGN 374
                  456899************998664 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.031
  ANAPC4_WD40  50 gklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                  + lL+ +  d evr+ ++ +g + h l+ +++ +v cl+ 
   EEA22591.1 392 DDLLVSGGCDREVRVWNMATGACTHLLRGHTS-TVRCLKM 430
                  67999**********************99988.6999986 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.059
  ANAPC4_WD40  37 edsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvkse 81 
                  ++ +vr+L     g l + +  d++ r+ ++++g+++++ls + +
   EEA22591.1 462 HQASVRCLG--IHGDLVVSGSYDTTARIWSISEGRCLRTLSGHFS 504
                  555666665..45889999999*************9999887655 PP

  == domain 4  score: 3.8 bits;  conditional E-value: 0.037
  ANAPC4_WD40  48 pdgklLavaysdgevrlldaesgkvvhsl 76 
                   dg+ +a +  d++vr+ d ++g++   l
   EEA22591.1 511 FDGRRIATGSLDTSVRIWDPNTGQCHAIL 539
                  59*********************986555 PP

  == domain 5  score: 10.3 bits;  conditional E-value: 0.00033
  ANAPC4_WD40  47 kpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgWg 90 
                  ++ g  L+ + sdg+vr+ +      +h l +++++ vt+l++ 
   EEA22591.1 550 QMRGDTLVTGGSDGSVRVWSLTRMAPIHRLAAHDNS-VTSLQFD 592
                  567999***************************995.***9986 PP

  == domain 6  score: 6.3 bits;  conditional E-value: 0.006
  ANAPC4_WD40  49 dgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                  d + ++ + sdg+v++ d ++g+++++ls+ +e av  + +
   EEA22591.1 592 DSTRIVSGGSDGRVKVWDLKTGQLLRELSTPAE-AVWRVAF 631
                  55678999*******************998877.4666665 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0      0.36   7.1e+02     209     250 ..     329     373 ..     306     376 .. 0.80
   2 ?    2.5   0.0     0.022        45     238     253 ..     400     415 ..     387     419 .. 0.87
   3 !   11.4   0.1   4.7e-05     0.093     222     252 ..     424     455 ..     419     458 .. 0.90
   4 ?    3.4   0.0     0.012        25     222     255 ..     465     498 ..     461     505 .. 0.85
   5 ?    2.8   0.0     0.019        38     233     254 ..     516     537 ..     502     544 .. 0.86
   6 ?   -1.7   0.0      0.41   8.2e+02     231     249 ..     554     572 ..     537     581 .. 0.81
   7 !    8.5   0.0   0.00034      0.67     225     259 ..     586     622 ..     578     650 .. 0.78

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.36
                 S---TT-ECEEEEET........TTTEEEEEETT-EEEEEETTTT CS
      Nup160 209 rksgasvalsldvavavvei...gqtylfalsrdgkLrvWnlltg 250
                  k g+++++ + + ++vv++   +++y++++  + k+ v +++ g
  EEA22591.1 329 NKGGRCTQKHVTPDQGVVTSlhlTSKYIVVALDNAKIHVYDTNGG 373
                 67899999**********999*************99999998765 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.022
                 TT-EEEEEETTTTEEE CS
      Nup160 238 rdgkLrvWnlltgkcl 253
                  d+++rvWn +tg c+
  EEA22591.1 400 CDREVRVWNMATGACT 415
                 599**********997 PP

  == domain 3  score: 11.4 bits;  conditional E-value: 4.7e-05
                 ET......TTTEEEEEETT-EEEEEETTTTEE CS
      Nup160 222 avavvei.gqtylfalsrdgkLrvWnlltgkc 252
                 +v++ ++ +++++ + srd +Lr+W+l tg c
  EEA22591.1 424 TVRCLKMsDKNTAISGSRDTTLRIWDLVTGNC 455
                 56778888*********************988 PP

  == domain 4  score: 3.4 bits;  conditional E-value: 0.012
                 ET.....TTTEEEEEETT-EEEEEETTTTEEEEE CS
      Nup160 222 avavveigqtylfalsrdgkLrvWnlltgkclat 255
                 +v++  i+ +++++ s d + r+W+++ g+cl+t
  EEA22591.1 465 SVRCLGIHGDLVVSGSYDTTARIWSISEGRCLRT 498
                 5566666778899999****************98 PP

  == domain 5  score: 2.8 bits;  conditional E-value: 0.019
                 EEEEETT-EEEEEETTTTEEEE CS
      Nup160 233 lfalsrdgkLrvWnlltgkcla 254
                 +++ s+d  +r+W+ +tg+c a
  EEA22591.1 516 IATGSLDTSVRIWDPNTGQCHA 537
                 77889***************76 PP

  == domain 6  score: -1.7 bits;  conditional E-value: 0.41
                 TEEEEEETT-EEEEEETTT CS
      Nup160 231 tylfalsrdgkLrvWnllt 249
                 ++l++  +dg +rvW+l+ 
  EEA22591.1 554 DTLVTGGSDGSVRVWSLTR 572
                 66777779********985 PP

  == domain 7  score: 8.5 bits;  conditional E-value: 0.00034
                 ......TTTEEEEEETT-EEEEEETTTTEEEEEEE-- CS
      Nup160 225 vvei..gqtylfalsrdgkLrvWnlltgkclatidll 259
                 v++   ++t +++  +dg+++vW+l+tg++l+  +++
  EEA22591.1 586 VTSLqfDSTRIVSGGSDGRVKVWDLKTGQLLRELSTP 622
                 4444557888888889**************9987766 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.7   0.4   3.2e-08   6.4e-05       2      47 ..     178     224 ..     177     225 .. 0.91

  Alignments for each domain:
  == domain 1  score: 22.7 bits;  conditional E-value: 3.2e-08
                 HHHHS-HHHHHHHHHTS-HHH.HHHHCTT-HHHHHHHTTHHHHHHHH CS
       F-box   2 tlsrLPsevlrhILerLplsd.llalrrVSkgwrilidsdrlwcksi 47 
                 +++  P+e+ + +L++++    l ++++VSk+w+ li++d  w++ +
  EEA22591.1 178 PFLAFPNEICLRVLSFVDDPKtLARASQVSKRWHELINDDITWKHLC 224
                 78999***********987777*******************999876 PP

>> F-box_5  F-box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.1   5.9e-07    0.0012       3      35 ..     181     213 ..     179     222 .. 0.91

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 5.9e-07
                 --GGGTHHHHHCC---HHHHHHHTTS-HHHHHH CS
     F-box_5   3 gfpDeVlecVlpyitsprDRnAvSlVCkrWYei 35 
                 +fp+e+  +Vl+++++p+  + +S+V krW+e+
  EEA22591.1 181 AFPNEICLRVLSFVDDPKTLARASQVSKRWHEL 213
                 68999**************************96 PP

>> PQQ_2  PQQ-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.1      0.03        59      69     145 ..     346     456 ..     337     533 .. 0.48
   2 !   14.5   0.9     1e-05      0.02      12     152 ..     483     624 ..     472     650 .. 0.81

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.03
       PQQ_2  69 vgaplvaegrvvvvasdg.qlialdaedGkr..............................lWstqqrseepaelrssaspava......gdtvvvges 130
                 v++ l+   + +vva d+  +  +d++ G++                              +W+++     +++l++  +++v+      ++t++ g  
  EEA22591.1 346 VTS-LHLTSKYIVVALDNaKIHVYDTNGGNQktleghvmgvwamvpwddllvsggcdrevrVWNMATG--ACTHLLRGHTSTVRclkmsdKNTAISGSR 441
                 555.4555555666666666666666666666666666666666666666666666666666663333..36666666666666666665555555555 PP

       PQQ_2 131 sgklvaldpkdGkvl 145
                 +  l + d+ +G+ +
  EEA22591.1 442 DTTLRIWDLVTGNCR 456
                 666666666666552 PP

  == domain 2  score: 14.5 bits;  conditional E-value: 1e-05
       PQQ_2  12 tGaelWrvdlar.......plgggvsravlsggtlfvatgggrlvaldaatGkvlWettlegpvvgaplvaegrvvvvasdgqlialdaedGkrlWstq 103
                 t a++W+ + +r        ++ + + a+ +g+++++++    +  +d++tG+ +   +    +vg   + ++ +v   sdg+++  + +     ++ +
  EEA22591.1 483 TTARIWSISEGRclrtlsgHFSQIYAIAF-DGRRIATGSLDTSVRIWDPNTGQCHAILQGHTSLVGQLQMRGDTLVTGGSDGSVRVWSLTRMAPIHRLA 580
                 55888999554444444435999999999.************************9999999999***999999998888*********99999999933 PP

       PQQ_2 104 qrseepaelrssaspavagdtvvvgessgklvaldpkdGkvlWerel.aa 152
                  +        s++s  +++ ++v g+s+g++ + d+k+G++l e +  a+
  EEA22591.1 581 AH------DNSVTSLQFDSTRIVSGGSDGRVKVWDLKTGQLLRELSTpAE 624
                 33......578999***************************988877444 PP

>> PALB2_WD40  Partner and localizer of BRCA2 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.2     0.021        41     281     322 ..     373     422 ..     359     442 .. 0.68
   2 ?    2.2   0.0     0.033        66     302     321 ..     443     462 ..     429     469 .. 0.79
   3 ?    3.6   0.1     0.013        25     302     350 ..     523     568 ..     478     569 .. 0.73
   4 !    6.7   0.0    0.0015       2.9     193     217 ..     596     620 ..     584     633 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.021
  PALB2_WD40 281 qtGryleGdvkdqlaaa....vltsGa....iavWdlllghctalllpes 322
                  + + leG v + +a      +l sG     + vW++  g ct ll  ++
  EEA22591.1 373 GNQKTLEGHVMGVWAMVpwddLLVSGGcdreVRVWNMATGACTHLLRGHT 422
                 45567777777777753333367777433337888888888888887665 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.033
  PALB2_WD40 302 GaiavWdlllghctalllpe 321
                  ++ +Wdl+ g+c+ +l+ +
  EEA22591.1 443 TTLRIWDLVTGNCRGVLVGH 462
                 5789**********999865 PP

  == domain 3  score: 3.6 bits;  conditional E-value: 0.013
  PALB2_WD40 302 GaiavWdlllghctalllpesdesWslv.rWsgtdsqllaGqkdGsvlvy 350
                  ++ +Wd   g+c a+l  ++    slv +      +l++G  dGsv v+
  EEA22591.1 523 TSVRIWDPNTGQCHAILQGHT----SLVgQLQMRGDTLVTGGSDGSVRVW 568
                 4799************98655....6662334455678889999998876 PP

  == domain 4  score: 6.7 bits;  conditional E-value: 0.0015
  PALB2_WD40 193 llgttvlnniviWnlktGqllkkie 217
                 +++   + ++ +W+lktGqll++++
  EEA22591.1 596 IVSGGSDGRVKVWDLKTGQLLRELS 620
                 66777788999**********9986 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0     0.049        97      14      62 ..     394     442 ..     347     454 .. 0.62
   2 ?    3.7   0.0     0.017        33      14     124 ..     394     506 ..     387     510 .. 0.69
   3 !   10.8   0.0   0.00011      0.21       2     109 ..     505     610 ..     504     626 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.049
   WD40_like  14 lilyGgkddkctvlkleslesvsivesfedSvifvklldddlilvvtlD 62 
                 l++ Gg d +++v ++ ++    ++ + +  v   k+ d++  + ++ D
  EEA22591.1 394 LLVSGGCDREVRVWNMATGACTHLLRGHTSTVRCLKMSDKNTAISGSRD 442
                 3444555555555555555555555555555555555555555555555 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.017
   WD40_like  14 lilyGgkddkctvlkleslesvsivesfedSvifvklldddlilvvtlDGtillsllenee.evenekieedistvkviddklliGtn..kGsiyvfsk 109
                 l++ Gg d +++v ++ ++    ++ + +  v   k+ d++  + ++ D t+   +l  ++        +  + +  + +d ++ G++  +  i+  s+
  EEA22591.1 394 LLVSGGCDREVRVWNMATGACTHLLRGHTSTVRCLKMSDKNTAISGSRDTTLRIWDLVTGNcRGVLVGHQASVRCLGIHGDLVVSGSYdtTARIWSISE 492
                 677799999999999999999999999999999999999999999999999988888877742223344455556666666666666411344555555 PP

   WD40_like 110 dlqleevllgqsseI 124
                    +  +l+g+ s+I
  EEA22591.1 493 G-RCLRTLSGHFSQI 506
                 5.5566666666666 PP

  == domain 3  score: 10.8 bits;  conditional E-value: 0.00011
   WD40_like   2 eiYsidiskkgslilyGgkddkctvlkleslesvsivesfedSvifvklldddlilvvtlDGtillslleneeev.enekieedistvkviddklliGt 99 
                 +iY+i +  +g  i+ G+ d  +++ + ++++   i+++ + S++   ++ +d ++ +  DG +    l+    + +    ++ ++  + +  +++ G+
  EEA22591.1 505 QIYAIAF--DGRRIATGSLDTSVRIWDPNTGQCHAILQGHT-SLVGQLQMRGDTLVTGGSDGSVRVWSLTRMAPIhRLAAHDNSVTSLQFDSTRIVSGG 600
                 7999988..9999************************9987.566666789999**********99999999966155678899*************** PP

   WD40_like 100 nkGsiyvfsk 109
                 + G + v++ 
  EEA22591.1 601 SDGRVKVWDL 610
                 ****999764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (717 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       496  (0.0276647); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.73u 0.31s 00:00:01.04 Elapsed: 00:00:00.49
# Mc/sec: 4379.98
//
Query:       EEA22592.1  [L=555]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.5e-08   33.1   7.2    4.5e-08   33.1   7.2    1.8  2  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain
    7.2e-06   25.1   0.2      1e-05   24.6   0.2    1.2  1  Fungal_trans_2  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.1   7.2     5e-12   4.5e-08       2      34 ..      10      42 ..       9      45 .. 0.92
   2 ?   -2.8   0.1      0.84   7.5e+03      16      27 ..     144     153 ..     137     155 .. 0.70

  Alignments for each domain:
  == domain 1  score: 33.1 bits;  conditional E-value: 5e-12
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfys 34
                +C  Cr++K+KCd+ +P C+nC+ ++++C  y+
  EEA22592.1 10 GCYLCRRRKIKCDEARPGCRNCEIYGKTCPGYR 42
                799**************************8776 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.84
                 SSSS-HHHHHCT CS
     Zn_clus  16 kkPaCsnCkkln 27 
                 ++P  s+C ++ 
  EEA22592.1 144 GNP--SSCLRWA 153
                 678..8899885 PP

>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.6   0.2   1.1e-09     1e-05      48     238 ..     160     340 ..     133     378 .. 0.74

  Alignments for each domain:
  == domain 1  score: 24.6 bits;  conditional E-value: 1.1e-09
  Fungal_trans_2  48 fhlqskgpkdslereakrykslalkelqealaelsstlsrnekykdiLaaiLllcsieissgdvsdwrvhLeaatsliksrggskasssslsska 142
                     +  ++  ++ +l+ +a++ + lal++l+eal+++ ++ +     +++La+iLll+++e ++g++ +  + ++a  +l++++       ++l+ k 
      EEA22592.1 160 TSYANEAHDRHLSLKARQRYGLALNGLKEALSTPVEKVQ-----DSTLATILLLVIFEDINGERAQLESSHTAGLELVARLHTY----RRLDGKY 245
                     3334444555589999999********************.....************************9888888888888877....4555555 PP

  Fungal_trans_2 143 rfllrifayldi.lssttlgrgpsfpseeyekllenkkeesdsgldplmGcsnslilliseisrLarekrsarkd...seleplsileeaseleq 233
                     + +l +fay  + ++ + lg +p+++     +l+++     ++ l++lmG+ + l +   ++ +L ++ + + +    s ++ ++ l++a++l +
      EEA22592.1 246 SRCLFNFAYTQLqIQILGLGAQPKIDLHFLIDLFDQ-----SDPLQSLMGIVTKLSQFVLDVPALLSDGNPQYNIadlSLEDLRNGLSRAQSLDE 335
                     555555666555144444454444444444444444.....888899999988888887777666555444444345555555555666666666 PP

  Fungal_trans_2 234 rllsw 238
                     +l+ w
      EEA22592.1 336 ELCLW 340
                     66555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (555 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       409  (0.0228122); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.44
# Mc/sec: 3755.62
//
Query:       EEA22593.1  [L=305]
Description: mitochondrial phosphate transporter Pic2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    3.1e-43  145.6   3.7    2.1e-14   53.2   0.1    3.0  3  Mito_carr  Mitochondrial carrier protein


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.1   0.0   2.6e-18   4.6e-14       8      94 ..      20     103 ..      15     106 .. 0.86
   2 !   53.2   0.1   1.2e-18   2.1e-14       5      95 ..     113     199 ..     109     201 .. 0.93
   3 !   40.2   0.3   1.3e-14   2.4e-10       7      93 ..     216     297 ..     212     299 .. 0.95

  Alignments for each domain:
  == domain 1  score: 52.1 bits;  conditional E-value: 2.6e-18
                 HHHHHHHHHHH..HHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
   Mito_carr   8 ellaGglagav..atlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlll 94 
                 ++ + +l+g++  +++++tPld+vK+r q++++ +k+      l++ ++i+ +eG+rg + G++p++++++ + a k +lye++k ++ 
  EEA22593.1  20 YFTSCALGGIIgpTHTAVTPLDLVKCRRQVDPNIYKS-----NLSAWRSIFAKEGIRGVFFGWSPTFVGYSFQGAGKYGLYEVFKYWYG 103
                 44455555555446999*****************999.....689***************************************98875 PP

  == domain 2  score: 53.2 bits;  conditional E-value: 1.2e-18
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCT CS
   Mito_carr   5 vlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlllk 95 
                 +l +l a++ a  +a ++ +P++ +K+r+qt    ++++    +++  +k + ++G+ gly+Gl p + r++p+++ kf+++e + +++++
  EEA22593.1 113 TLVYLGASASAEFFADMALCPFEAIKVRMQTTLPPYAST----LREGWSKAVAQDGFGGLYKGLYPLWARQIPYTMTKFATFEEVVNMIYR 199
                 567788999**************************9884....9*****************************************999875 PP

  == domain 3  score: 40.2 bits;  conditional E-value: 1.3e-14
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   7 kellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrll 93 
                  +++ G lag++ ++v +P dv+  +l +++k +++     ++ ++++iy + G++gl+ Gl +++ +    ++ ++++y+++k +l
  EEA22593.1 216 VSFAGGYLAGILCAIVSHPADVMVSKLNAERKAGES-----AMTAVSRIYSKIGFAGLWNGLPVRIAMLGTLTGFQWLIYDSFKVFL 297
                 67999****************************999.....99****************************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (305 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       322  (0.0179597); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.25s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2170.75
//
Query:       EEA22594.1  [L=267]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
      0.038   14.1   4.2      0.045   13.8   1.6    1.9  2  Mito_fiss_reg  Mitochondrial fission regulator


Domain annotation for each model (and alignments):
>> Mito_fiss_reg  Mitochondrial fission regulator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0     0.026   4.7e+02     178     215 ..      15      55 ..       1      80 [. 0.51
   2 ?   13.8   1.6   2.5e-06     0.045     130     216 ..     102     202 ..     101     221 .. 0.63

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.026
  Mito_fiss_reg 178 lppppppppppi...ppespsvldssnsaielikqrrgakk 215
                     +p pp+  +     + + ++ l++ ++  +li+ r++  k
     EEA22594.1  15 NTPNPPSIELAYkkkCIQLKKRLNEIEAENDLIRARNKRAK 55 
                    22333322222233323456666677777777777766544 PP

  == domain 2  score: 13.8 bits;  conditional E-value: 2.5e-06
  Mito_fiss_reg 130 akLRaQIAkIVaaqeasnssaslelsdtpdllepksssaspsl..ep.sss...........lppppppppppippespsvldssnsaielikqrr 211
                    a+LRa  A+IV+ ++a+n ++ ++++++ ++ e+++++++ +l  +  ++s           +    + +p p  + s    +++n+ +++++++r
     EEA22594.1 102 AELRAKAAAIVTSAHAQNTQGVMDDETEGSSEEQPPTPQERPLrvKRsRKSnlafedieaeaAMQYEANSPEPKGNDSGYNNNNNNNNTDIDRDNR 197
                    58*****************99999998888888888888887754223233677788777642245555566633333333444555566666665 PP

  Mito_fiss_reg 212 gakkt 216
                    +  + 
     EEA22594.1 198 NIGTG 202
                    53333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (267 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1031  (0.0575046); expected 358.6 (0.02)
Passed bias filter:                      465  (0.0259356); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.30s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1841.52
//
Query:       EEA22595.1  [L=533]
Description: YagE family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.3e-51  172.6   0.1    1.5e-50  171.7   0.1    1.4  1  DUF155    Uncharacterised ACR, YagE family COG1723
  ------ inclusion threshold ------
      0.094   13.2   0.0       0.26   11.8   0.0    1.8  1  UPF0449   Uncharacterised protein family UPF0449


Domain annotation for each model (and alignments):
>> DUF155  Uncharacterised ACR, YagE family COG1723
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  171.7   0.1   1.7e-54   1.5e-50       1     175 [.     308     479 ..     308     480 .. 0.95

  Alignments for each domain:
  == domain 1  score: 171.7 bits;  conditional E-value: 1.7e-54
      DUF155   1 vfiFknGsvVfwgldeeeeknflnkllkflneeselpreeeqeteeleyvydeqsessrikgdvivl.kskslleklaiShalaqSvkLdvlEesldel 98 
                 vf+F++G+vV+wg++ +ee++fl+++ kf++    l++e+ q  e+++++y++ +++ ri++d i l + ++ + klaiShal+qSvk +++E++++e+
  EEA22595.1 308 VFLFDYGTVVIWGMTPAEETRFLADVAKFATAI--LSTEDRQ-VENFNFYYAR-DYQARIYNDFISLrEPRNQMIKLAISHALSQSVKTSLFEDLVSET 402
                 8****************************9886..5555555.89****9988.888**********88889*************************** PP

      DUF155  99 lestekipkelakkgklklsrkellkktgellslrinlnlkselldtPdffWeepeleslyeavseyleikeRikiL 175
                 ++ t ++p+++ak+g+++++rk++  ++gel+ lrin+ l+ ++ld+P+++W ep+le++y+av++yle+++R+ +L
  EEA22595.1 403 IAATAPFPAQIAKTGSVNMTRKQINMQIGELFILRINIHLQGSVLDSPELMWAEPQLEPVYQAVRTYLEMDQRVGLL 479
                 *************************************************************************9877 PP

>> UPF0449  Uncharacterised protein family UPF0449
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   2.9e-05      0.26      54      97 ..     456     499 ..     434     503 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 2.9e-05
     UPF0449  54 eaeveelYeqvrtylelnerLeeakeeLkqkceeLktageeLee 97 
                 e + e +Y+ vrtyle+++r     e+L    + L ++ ++L++
  EEA22595.1 456 EPQLEPVYQAVRTYLEMDQRVGLLTERLDVIADLLAVLKDQLSH 499
                 667999**********************9999999999988875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (533 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       837  (0.0466841); expected 358.6 (0.02)
Passed bias filter:                      589  (0.0328518); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.32s 00:00:00.97 Elapsed: 00:00:00.49
# Mc/sec: 3271.76
//
Query:       EEA22596.1  [L=387]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.3e-12   46.9   1.2    3.3e-12   46.9   1.2    4.9  4  U3_snoRNA_assoc  U3 snoRNA associated


Domain annotation for each model (and alignments):
>> U3_snoRNA_assoc  U3 snoRNA associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -5.2   7.5         1   1.8e+04      28      50 ..      50      90 ..      20     129 .. 0.54
   2 ?    0.7   0.5     0.048   8.6e+02      11      52 ..     108     144 ..      95     167 .. 0.50
   3 ?   -6.1  15.5         1   1.8e+04      28      53 ..     192     223 ..     165     254 .. 0.48
   4 !   46.9   1.2   1.8e-16   3.3e-12       1      87 [.     285     359 ..     285     362 .. 0.81

  Alignments for each domain:
  == domain 1  score: -5.2 bits;  conditional E-value: 1
  U3_snoRNA_assoc 28 n.................eepkkarkkkkkekllel.kekr 50
                                       e +  +++k  + k +   k++r
       EEA22596.1 50 MgtatrqgnvasprmngsETATNTKRKTLESKTNGHsKKRR 90
                     13444455555555545433333333333333333323333 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.048
  U3_snoRNA_assoc  11 ee...redeeeaeeekskhineepkkarkkkkkekllelkekrpk 52 
                      +e   ++ + + ++++        +k+ +  ++    ++ +k+p 
       EEA22596.1 108 QEapdDNVTIQIPAAR--------EKKIRNGTESTTPDRSAKKPS 144
                      3322233333333333........333444444444444333332 PP

  == domain 3  score: -6.1 bits;  conditional E-value: 1
  U3_snoRNA_assoc  28 n...............eepkkarkkkkkekllelkekrpkd 53 
                      +               +         +++k+ el +k+++ 
       EEA22596.1 192 DnsvqllalkvqaqkqK---------EAKKRDELLQKEKRR 223
                      24444555443222222.........222222222222221 PP

  == domain 4  score: 46.9 bits;  conditional E-value: 1.8e-16
  U3_snoRNA_assoc   1 lLPdeilealee.redeeeaeeekskhineepkkarkkkkkekllelkekrpkdvkkGpvsvrVlkssnssklaPkaekkirnskekw 87 
                      lLPdeil+a++  r +++++ee+            +k+++k+++  ++++++kd+++G+v++rVl+++++  l+Pk +  +r++k +w
       EEA22596.1 285 LLPDEILNAEPIhRLPSPPPEEQ------------QKTSTKQHKFFKEDRPAKDIRRGDVTIRVLENKKE-MLPPKNSAVGRHVKAAW 359
                      7******9999989999998433............22333333334589*****************7766.****************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (387 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2574  (0.143566); expected 358.6 (0.02)
Passed bias filter:                      617  (0.0344135); expected 358.6 (0.02)
Passed Vit filter:                        84  (0.00468515); expected 17.9 (0.001)
Passed Fwd filter:                        24  (0.00133861); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.94u 0.35s 00:00:01.29 Elapsed: 00:00:00.51
# Mc/sec: 2272.99
//
Query:       EEA22597.1  [L=234]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-49  167.6   0.5    1.5e-49  167.1   0.5    1.2  1  CTK3      CTD kinase subunit gamma CTK3
      2e-20   72.7   6.5      2e-20   72.7   6.5    1.8  2  CTK3_C    CTD kinase subunit gamma CTK3 C-terminus
  ------ inclusion threshold ------
      0.049   14.0   0.0       0.11   12.9   0.0    1.5  1  DUF3873   Domain of unknown function, B. Theta Gene descripti


Domain annotation for each model (and alignments):
>> CTK3  CTD kinase subunit gamma CTK3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  167.1   0.5   2.5e-53   1.5e-49       1     122 [.       2     122 ..       2     123 .. 0.98

  Alignments for each domain:
  == domain 1  score: 167.1 bits;  conditional E-value: 2.5e-53
                 --HHHHHHHHHHHHTT--SSGGGTHHHHHHHHHTGGGHHHHHHHHHHHHHHS-HHHHHHHHHHHHHHHHHHHHTT--S..THHHHHHHTHHHHHHHHS- CS
        CTK3   1 mDpFEvrsqFsqlLrkLtasvqslqkaaqfAlknkdkeedlfscileqlesadlNtranilyfidllleeslkegqsekspYveslkrdilklvdsvvP 99 
                 +DpFEvr++F+++L++L+a v+s+q+aaq+Alk++d++edl+scileqle++++N+rani+yfi++++e + ke++    +Yv++++rd+l++vdsv+P
  EEA22597.1   2 ADPFEVRMRFTTQLQHLSAAVTSSQRAAQYALKYRDMDEDLHSCILEQLERNNMNNRANIMYFIEHFCELASKENHL---NYVRMIQRDMLTIVDSVAP 97 
                 6*************************************************************************999...7****************** PP

                 ..HHHHHHHHHHHHHHHHHHHTTSS CS
        CTK3 100 ..gsgaaNlksvrkilkslklksll 122
                   gsgaaN+k+vr++l++l+ k++l
  EEA22597.1  98 adGSGAANVKHVRRVLQGLQDKNFL 122
                 *99******************9988 PP

>> CTK3_C  CTD kinase subunit gamma CTK3 C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0      0.61   3.6e+03      46      64 ..      34      52 ..      20      57 .. 0.76
   2 !   72.7   6.5   3.3e-24     2e-20       1      68 [.     170     231 ..     170     232 .. 0.97

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.61
      CTK3_C 46 etsdlneddeeealeelee 64
                +++d++ed +   le+le 
  EEA22597.1 34 KYRDMDEDLHSCILEQLER 52
                5778888888888777765 PP

  == domain 2  score: 72.7 bits;  conditional E-value: 3.3e-24
      CTK3_C   1 skkqilkRiEeDRErhKRlrEniWvvprskekslateaEfenlWeetsdlneddeeealeeleelnea 68 
                 +k+qi++RiEeDREr+KRlrE++W v+ ++      + Ef++ W+e+sd++edd+  a+ee+ e++++
  EEA22597.1 170 DKRQIEQRIEEDRERNKRLRESMWTVSGDN------KGEFQQCWDEVSDIGEDDYLGAEEEFGERRQM 231
                 79***************************9......99**************************9988 PP

>> DUF3873  Domain of unknown function, B. Theta Gene description (DUF3873)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   1.8e-05      0.11      27      54 ..      24      51 ..      14      58 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.8e-05
     DUF3873 27 rrkrikyyqYDYrhtdgeLFSvvaktle 54
                 ++r   y   Yr++d++L S++ + le
  EEA22597.1 24 SSQRAAQYALKYRDMDEDLHSCILEQLE 51
                4678889999*************99996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (234 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1024  (0.0571142); expected 358.6 (0.02)
Passed bias filter:                      580  (0.0323498); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.49
# Mc/sec: 1440.03
//
Query:       EEA22598.1  [L=314]
Description: pyrroline-5-carboxylate reductase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.1e-33  114.1   2.0    3.3e-33  114.0   1.0    1.6  2  P5CR_dimer     Pyrroline-5-carboxylate reductase dimerisation
    3.5e-10   40.3   0.1    1.3e-09   38.5   0.0    2.1  2  F420_oxidored  NADP oxidoreductase coenzyme F420-dependent


Domain annotation for each model (and alignments):
>> P5CR_dimer  Pyrroline-5-carboxylate reductase dimerisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0         1   9.1e+03      42      54 ..     150     162 ..     131     173 .. 0.57
   2 !  114.0   1.0   3.6e-37   3.3e-33       2     103 .]     200     302 ..     199     302 .. 0.96

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 1
                 HHHHHHHHHHHHH CS
  P5CR_dimer  42 laaqtvaGaakll 54 
                  +++++  +a+++
  EEA22598.1 150 TVVRAMPNTAAMV 162
                 3444455555554 PP

  == domain 2  score: 114.0 bits;  conditional E-value: 3.6e-37
                 CHHHHHHHHTTTHHHHHHHHHHHHHHHHHHTT--HHHHHHHHHHHHHHHHHHHHCHS.HHHHHHHH--TTSHHHHHHHHHHHTTHHHHHHHHHHHHHHH CS
  P5CR_dimer   2 kqldavtalsGsgpAyvflliealadagvklGlsreeArelaaqtvaGaaklllese.paelrdkvtspgGtTiaglkeleegglraavieaveaaakr 99 
                 +q+d++tal+GsgpA+ +l+ie lad++v++Gl+r+eA+ +a q+++G++++++++e p+ +++k++spgG+Ti gl +le++g+r++v++av++a+  
  EEA22598.1 200 SQMDVCTALAGSGPAFAALMIEGLADGAVAMGLPRAEAQLMACQVLKGTVSMIESGEhPSIVKEKISSPGGCTIGGLLVLEDAGVRGSVARAVREATCV 298
                 79***************************************************97778**************************************988 PP

                 HHHH CS
  P5CR_dimer 100 skel 103
                 ++el
  EEA22598.1 299 ASEL 302
                 7775 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.5   0.0   1.5e-13   1.3e-09      24      97 .]      48     127 ..      13     127 .. 0.88
   2 ?   -3.5   0.0       1.8   1.6e+04      10      23 ..     219     232 ..     219     242 .. 0.73

  Alignments for each domain:
  == domain 1  score: 38.5 bits;  conditional E-value: 1.5e-13
                    -GGCEEEEEESSCCCHHHHHHHHC......-EEECECHHHHHHH-SEEEE-S-HHHHHHHHHHC.GHHHHTTSEEEEESSS CS
  F420_oxidored  24 qpheivvansrnpekaeelaeelg......vkvtavdneeaaeeadvvvlavkpedveevlsel.akdalkgklvisvlag 97 
                    +p++++ a+ r++++a+ ++++++      vk+ + +n + ++ead+++l +kp+++++vl+   ++dalkgkl+isvlag
     EEA22598.1  48 TPTKFI-ACIRSEQTAARIRNAVEpypkfpVKILQNENVTGVKEADIIILGCKPYMLKDVLDVPgMRDALKGKLLISVLAG 127
                    577888.999***********999999**********************************86679*************97 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 1.8
                    HHHHHHHHHHHTTS CS
  F420_oxidored  10 mgealasgllaaga 23 
                    m+e+la g++a g 
     EEA22598.1 219 MIEGLADGAVAMGL 232
                    77899999999885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (314 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       343  (0.019131); expected 358.6 (0.02)
Passed bias filter:                      310  (0.0172904); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2279.07
//
Query:       EEA22599.1  [L=878]
Description: voltage-gated chloride channel, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.1e-89  300.2  28.3    2.1e-89  300.2  28.3    1.4  2  Voltage_CLC  Voltage gated chloride channel
    0.00022   21.6   0.0      0.035   14.5   0.0    2.4  2  CBS          CBS domain


Domain annotation for each model (and alignments):
>> Voltage_CLC  Voltage gated chloride channel
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.2      0.62   5.5e+03      90     178 ..     180     191 ..     167     201 .. 0.60
   2 !  300.2  28.3   2.3e-93   2.1e-89       2     353 ..     268     651 ..     267     652 .. 0.91

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 0.62
                  HHHHHHHHHHHHHHT-HHHHHHHHCTTTSTSS--TTHHHHHHHHHHHHHHHHHHCTTS-S-.T---...--GGGHHHHHHHHHHHHHHH CS
  Voltage_CLC  90 lvaaGaAAGiAAaFnaPlgGvlfalEevsrefslrallpvfvasvvaalvlrlllgeepafgeveslfalsllelilfvllGilgGllg 178
                  lva+G+A G                                                                             ll+
   EEA22599.1 180 LVASGIAVG-----------------------------------------------------------------------------LLA 191
                  333333333.............................................................................333 PP

  == domain 2  score: 300.2 bits;  conditional E-value: 2.3e-93
                  HHHHHHHCCCCC-GGGSC-SHHHHHHHCTTSS--..-HHHHHHHHHHHHHHHHCTT-S-BTHHHHHHHHHHHHHHHHHH.TT.--SHHHHH.HHHHHH CS
  Voltage_CLC   2 ggllagllvklvapeaagsGipevkaalngvkgp..lslrvllvkflasvltvgsGlslGreGplvqiGAavgsglsrl.lklsrndrdrr.lvaaGa 95 
                  ++++a +lv+ +ap+a+ sGipe+k++l g+  +  +  ++l++k l+++l+v+sG+ +G+eGplv+++++++++l +    l++n++++r +++a+a
   EEA22599.1 268 FATCACILVRSYAPYAKHSGIPEIKTVLGGFVMKrfMGGWTLVIKSLGLCLVVASGMWVGKEGPLVHVACCCANILMKPfDTLNNNEARKReVLSAAA 365
                  7899***************************9999******************************************663555788888889****** PP

                  HHHHHHHHT-HHHHHHHHCTTTSTSS--TTHHHHHHHHHHHHHHHHHHCTTS-S....-.T---...--GGGHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Voltage_CLC  96 AAGiAAaFnaPlgGvlfalEevsrefslrallpvfvasvvaalvlrlllgeepa....fgeveslfalsllelilfvllGilgGllgalfvrlllkve 189
                  AAGi++aF+aP+gGvlf+lE++s +f  ++++ +fv++ vaa++l++l+  ++     ++ v+ + +++ +e+i+f++lGi+gGl+g+lf++l++kv+
   EEA22599.1 366 AAGISVAFGAPIGGVLFSLEQLSYYFPDKTMWQSFVCASVAAVTLQALNPFHTGkivlYQ-VTYTREWHRFEMIPFMILGIFGGLYGGLFIKLNMKVA 462
                  ***********************99999********************777755555444.776669******************************* PP

                  HHHHCHHCHHHH.HHHHHHHHHHHHHHHCCCSCC.CSSSSCCHHHHHCTT-S-...............HHHHHH...HHHHHHHHHHHHHCTT-CSBS CS
  Voltage_CLC 190 rlfrkleklkik.krlepalvgllvgllglllpasvlgggyeliasllegstl...............llsllllllllllkllataltlgsgvpgGi 271
                  r+++++       + le+a+v+++++l+ ++    +   + el+ +l++++++                  ++lll+++++ ++++++++g+ +p+Gi
   EEA22599.1 463 RWRKSRG---WAfPLLEIAVVAVITALVNFPNKF-MRAQSSELVYQLFAECATttddqldlcktgaasFGVIALLLMAAMAGFCLASVSFGLEIPAGI 556
                  *999873...232466*************99855.555666778888877766778889999999998889999999********************* PP

                  HHHHHHHHHHHHHHHHHHHHHH-C............TSSC....HHHHHHCCTHHHHHCCS-HHHHHHHHHHCC--GCCHHHHHHHHHHHHHHHC CS
  Voltage_CLC 272 faPsLviGAalGrlvglvlalllp............gaass.dpgafalvGmaaflagvtrapltaiviviEltgdlelllplmlavliAkavad 353
                  ++PsL+iGA++Gr++g +++++ +             + ++ +p+++a++G+a+ l+g+tr++++++vi++Eltg+l++++p+m+av+++k+++d
   EEA22599.1 557 ILPSLAIGALFGRALGIAVEMWQAafptfvlfqscePDIPCiTPATYAIIGAASALGGATRMTVSIVVIMFELTGALTYVIPIMIAVMLSKWCGD 651
                  ****************99999955677999999***889999**************************************************986 PP

>> CBS  CBS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.0   3.9e-06     0.035      17      52 ..     703     740 ..     686     745 .. 0.87
   2 !    4.5   0.0    0.0055        49       5      51 ..     780     825 ..     775     825 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 3.9e-06
                 BHHHHHHHHHHHTSSEEEEE.ETTT.BEEEEEEHHHHH CS
         CBS  17 tleealelmrekgvsrlPVV.dedg.klvGivtlrDll 52 
                 t+e +  l+++++++++PVV d ++  l+G +t++ l 
  EEA22599.1 703 TIESLKSLLAQTRYRGFPVVlDTSNpILLGFITRKELS 740
                 7889999999999******9888887899*****9885 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.0055
                 SBSSCEEEETTSBHHHHHHHHHHHTSSEEEEEETTTBEEEEEEHHHH CS
         CBS   5 mtrdvvtvppdttleealelmrekgvsrlPVVdedgklvGivtlrDl 51 
                 m   ++t++   + + +l ++ + g++ ++ V   g+l G++t++D+
  EEA22599.1 780 MDQTPITLNSHINFSIVLGMFQRLGLRYVLFV-HKGHLRGLLTKKDV 825
                 55567899999999999999977667555336.7999********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (878 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       517  (0.028836); expected 358.6 (0.02)
Passed bias filter:                      288  (0.0160634); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.69u 0.25s 00:00:00.94 Elapsed: 00:00:00.47
# Mc/sec: 5583.54
//
Query:       EEA22600.1  [L=882]
Description: voltage-gated chloride channel, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.1e-89  300.2  28.3    2.1e-89  300.2  28.3    1.4  2  Voltage_CLC  Voltage gated chloride channel
    0.00022   21.6   0.0      0.036   14.5   0.0    2.4  2  CBS          CBS domain


Domain annotation for each model (and alignments):
>> Voltage_CLC  Voltage gated chloride channel
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.2      0.62   5.5e+03      90     178 ..     184     195 ..     171     205 .. 0.60
   2 !  300.2  28.3   2.4e-93   2.1e-89       2     353 ..     272     655 ..     271     656 .. 0.91

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 0.62
                  HHHHHHHHHHHHHHT-HHHHHHHHCTTTSTSS--TTHHHHHHHHHHHHHHHHHHCTTS-S-.T---...--GGGHHHHHHHHHHHHHHH CS
  Voltage_CLC  90 lvaaGaAAGiAAaFnaPlgGvlfalEevsrefslrallpvfvasvvaalvlrlllgeepafgeveslfalsllelilfvllGilgGllg 178
                  lva+G+A G                                                                             ll+
   EEA22600.1 184 LVASGIAVG-----------------------------------------------------------------------------LLA 195
                  333333333.............................................................................333 PP

  == domain 2  score: 300.2 bits;  conditional E-value: 2.4e-93
                  HHHHHHHCCCCC-GGGSC-SHHHHHHHCTTSS--..-HHHHHHHHHHHHHHHHCTT-S-BTHHHHHHHHHHHHHHHHHH.TT.--SHHHHH.HHHHHH CS
  Voltage_CLC   2 ggllagllvklvapeaagsGipevkaalngvkgp..lslrvllvkflasvltvgsGlslGreGplvqiGAavgsglsrl.lklsrndrdrr.lvaaGa 95 
                  ++++a +lv+ +ap+a+ sGipe+k++l g+  +  +  ++l++k l+++l+v+sG+ +G+eGplv+++++++++l +    l++n++++r +++a+a
   EEA22600.1 272 FATCACILVRSYAPYAKHSGIPEIKTVLGGFVMKrfMGGWTLVIKSLGLCLVVASGMWVGKEGPLVHVACCCANILMKPfDTLNNNEARKReVLSAAA 369
                  7899***************************9999******************************************663555788888889****** PP

                  HHHHHHHHT-HHHHHHHHCTTTSTSS--TTHHHHHHHHHHHHHHHHHHCTTS-S....-.T---...--GGGHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Voltage_CLC  96 AAGiAAaFnaPlgGvlfalEevsrefslrallpvfvasvvaalvlrlllgeepa....fgeveslfalsllelilfvllGilgGllgalfvrlllkve 189
                  AAGi++aF+aP+gGvlf+lE++s +f  ++++ +fv++ vaa++l++l+  ++     ++ v+ + +++ +e+i+f++lGi+gGl+g+lf++l++kv+
   EEA22600.1 370 AAGISVAFGAPIGGVLFSLEQLSYYFPDKTMWQSFVCASVAAVTLQALNPFHTGkivlYQ-VTYTREWHRFEMIPFMILGIFGGLYGGLFIKLNMKVA 466
                  ***********************99999********************777755555444.776669******************************* PP

                  HHHHCHHCHHHH.HHHHHHHHHHHHHHHCCCSCC.CSSSSCCHHHHHCTT-S-...............HHHHHH...HHHHHHHHHHHHHCTT-CSBS CS
  Voltage_CLC 190 rlfrkleklkik.krlepalvgllvgllglllpasvlgggyeliasllegstl...............llsllllllllllkllataltlgsgvpgGi 271
                  r+++++       + le+a+v+++++l+ ++    +   + el+ +l++++++                  ++lll+++++ ++++++++g+ +p+Gi
   EEA22600.1 467 RWRKSRG---WAfPLLEIAVVAVITALVNFPNKF-MRAQSSELVYQLFAECATttddqldlcktgaasFGVIALLLMAAMAGFCLASVSFGLEIPAGI 560
                  *999873...232466*************99855.555666778888877766778889999999998889999999********************* PP

                  HHHHHHHHHHHHHHHHHHHHHH-C............TSSC....HHHHHHCCTHHHHHCCS-HHHHHHHHHHCC--GCCHHHHHHHHHHHHHHHC CS
  Voltage_CLC 272 faPsLviGAalGrlvglvlalllp............gaass.dpgafalvGmaaflagvtrapltaiviviEltgdlelllplmlavliAkavad 353
                  ++PsL+iGA++Gr++g +++++ +             + ++ +p+++a++G+a+ l+g+tr++++++vi++Eltg+l++++p+m+av+++k+++d
   EEA22600.1 561 ILPSLAIGALFGRALGIAVEMWQAafptfvlfqscePDIPCiTPATYAIIGAASALGGATRMTVSIVVIMFELTGALTYVIPIMIAVMLSKWCGD 655
                  ****************99999955677999999***889999**************************************************986 PP

>> CBS  CBS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.5   0.0     4e-06     0.036      17      52 ..     707     744 ..     690     749 .. 0.87
   2 !    4.5   0.0    0.0055        50       5      51 ..     784     829 ..     779     829 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 4e-06
                 BHHHHHHHHHHHTSSEEEEE.ETTT.BEEEEEEHHHHH CS
         CBS  17 tleealelmrekgvsrlPVV.dedg.klvGivtlrDll 52 
                 t+e +  l+++++++++PVV d ++  l+G +t++ l 
  EEA22600.1 707 TIESLKSLLAQTRYRGFPVVlDTSNpILLGFITRKELS 744
                 7889999999999******9888887899*****9885 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.0055
                 SBSSCEEEETTSBHHHHHHHHHHHTSSEEEEEETTTBEEEEEEHHHH CS
         CBS   5 mtrdvvtvppdttleealelmrekgvsrlPVVdedgklvGivtlrDl 51 
                 m   ++t++   + + +l ++ + g++ ++ V   g+l G++t++D+
  EEA22600.1 784 MDQTPITLNSHINFSIVLGMFQRLGLRYVLFV-HKGHLRGLLTKKDV 829
                 55567899999999999999977667555336.7999********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (882 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       538  (0.0300073); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.29s 00:00:00.96 Elapsed: 00:00:00.47
# Mc/sec: 5641.08
//
Query:       EEA22601.1  [L=4898]
Description: midasin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   3.6e-127  419.0   0.0    3.7e-22   78.8   0.0    9.7  9  AAA_5            AAA domain (dynein-related subfamily)
    2.1e-48  162.9   2.8    4.2e-17   62.3   0.0    5.4  4  AAA_lid_7        Midasin AAA lid domain
    1.9e-30  105.7   2.5    2.2e-06   27.3   0.0    7.3  7  AAA_7            P-loop containing dynein motor region
    1.3e-29  102.3   0.4    1.8e-28   98.7   0.0    3.3  1  AAA_lid_5        Midasin AAA lid domain
    2.8e-29  102.2   0.6    0.00029   21.3   0.0    7.5  6  AAA              ATPase family associated with various cellul
    1.8e-28   99.0   0.0    4.3e-11   42.8   0.0    7.1  6  AAA_3            ATPase family associated with various cellul
    1.6e-27   97.0   9.0    4.9e-05   23.8   0.1    8.3  6  AAA_16           AAA ATPase domain
    6.6e-22   77.8   0.0    5.1e-06   26.6   0.0    8.0  7  Dynein_heavy     Dynein heavy chain region D6 P-loop domain
    1.6e-19   70.1   0.0       0.06   12.3   0.0    8.2  8  AAA_6            Hydrolytic ATP binding site of dynein motor 
    5.3e-18   65.6   2.4      0.049   13.9   0.0    8.8  6  AAA_22           AAA domain
    7.7e-17   61.8   0.1     0.0096   16.1   0.0    7.0  6  AAA_33           AAA domain
    1.7e-16   60.4   0.0      0.027   14.2   0.0    6.0  5  Sigma54_activat  Sigma-54 interaction domain
    3.6e-16   59.4   0.0     0.0073   16.3   0.0    7.6  6  AAA_14           AAA domain
    2.1e-14   54.2   0.1       0.13   12.8   0.0    7.5  6  AAA_18           AAA domain
    3.8e-14   52.8   0.0      0.035   13.8   0.0    7.3  6  AAA_30           AAA domain
    5.2e-14   52.3   1.2        0.1   12.6   0.0    6.6  6  TsaE             Threonylcarbamoyl adenosine biosynthesis pro
    1.8e-13   51.2   2.2        0.1   13.1   0.0    6.8  6  ABC_tran         ABC transporter
      1e-11   45.2   0.7       0.84   10.1   0.0    6.8  6  RNA_helicase     RNA helicase
      2e-11   44.2   0.3    0.00078   19.6   0.1    5.7  5  Sigma54_activ_2  Sigma-54 interaction domain
    3.4e-11   42.9   0.4         10    5.4   0.0    8.4  8  Mg_chelatase     Magnesium chelatase, subunit ChlI
    6.5e-11   42.5   2.2     0.0059   16.5   0.0    6.2  6  Rad17            Rad17 P-loop domain
    7.7e-11   41.6   0.4        8.1    5.7   0.0    8.4  8  Zeta_toxin       Zeta toxin
    1.5e-09   37.8   4.4       0.18   11.4   0.0    5.8  6  SRP54            SRP54-type protein, GTPase domain
    1.6e-09   38.2   2.6        3.2    8.1   0.1    6.7  6  AAA_19           AAA domain
    3.6e-09   36.7   6.7      0.041   13.8   0.0    6.3  5  NACHT            NACHT domain
    4.7e-09   36.4   3.9       0.21   11.5   0.2    6.1  5  RsgA_GTPase      RsgA GTPase
    5.1e-09   35.6   3.2     0.0041   16.2   0.0    6.2  6  T2SSE            Type II/IV secretion system protein
    1.2e-08   34.8   0.9        0.4   10.2   0.0    6.0  5  AAA_25           AAA domain
    3.6e-08   33.6   0.0         11    5.8   0.0    6.2  6  ATPase_2         ATPase domain predominantly from Archaea
    8.2e-08   31.9   0.4        2.5    7.5   0.0    6.0  6  TniB             Bacterial TniB protein
    1.3e-07   31.5   6.8       0.57    9.9   0.0    7.1  6  RuvB_N           Holliday junction DNA helicase RuvB P-loop d
    1.7e-07   30.7   1.4       0.62    9.2   0.1    5.6  6  DUF815           Protein of unknown function (DUF815)
    2.8e-07   30.5   0.0          6    6.6   0.0    5.7  5  IstB_IS21        IstB-like ATP binding protein
    7.8e-07   28.9   3.8       0.45   10.2   0.0    6.2  6  PduV-EutP        Ethanolamine utilisation - propanediol utili
    2.2e-06   27.3   1.3         23    4.8   0.1    6.3  6  AAA_29           P-loop containing region of AAA domain
    3.2e-06   27.4   2.4          6    7.1   0.0    6.4  6  Roc              Ras of Complex, Roc, domain of DAPkinase
    3.5e-06   27.1   1.5       0.45   10.6   0.0    6.0  6  MMR_HSR1         50S ribosome-binding GTPase
    6.6e-06   26.0   0.3        5.3    6.7   0.0    5.7  6  AAA_24           AAA domain
    7.7e-06   26.0   0.0       0.15   12.1   0.0    3.7  2  CbiA             CobQ/CobB/MinD/ParA nucleotide binding domai
    1.2e-05   24.6   0.1       0.38    9.8   0.0    4.7  5  MCM              MCM P-loop domain
    1.6e-05   25.2   9.7        0.8    9.9   0.3    6.0  5  AAA_28           AAA domain
    0.00019   21.5   0.5        7.9    6.4   0.0    5.0  4  ResIII           Type III restriction enzyme, res subunit
    0.00027   20.9   0.0        2.9    7.7   0.0    3.8  3  Bac_DnaA         Bacterial dnaA  protein
    0.00034   20.1   2.1        8.8    5.7   0.0    5.5  5  SRPRB            Signal recognition particle receptor beta su
    0.00073   18.8   1.5          4    6.5   0.0    4.6  5  TIP49            TIP49 P-loop domain
    0.00089   19.1   1.2       0.84    9.5   0.0    5.5  3  CPT              Chloramphenicol phosphotransferase-like prot
     0.0035   17.1   0.0         13    5.4   0.0    4.3  4  Viral_helicase1  Viral (Superfamily 1) RNA helicase
     0.0093   15.3   3.2        1.8    7.8   0.1    4.4  4  DnaB_C           DnaB-like helicase C terminal domain
  ------ inclusion threshold ------
      0.013   14.9   0.3        9.3    5.6   0.0    4.0  4  KTI12            Chromatin associated protein KTI12
      0.015   14.6   0.4         15    4.8   0.0    4.2  3  ATPase           KaiC
      0.021   14.1   0.0        4.8    6.3   0.0    3.6  3  KAP_NTPase       KAP family P-loop domain
      0.041   13.3   0.4        3.4    7.1   0.0    3.6  3  PhoH             PhoH-like protein
      0.045   13.6   0.5         22    4.8   0.0    3.8  3  dNK              Deoxynucleoside kinase
      0.057   13.2   0.0       0.81    9.4   0.0    3.0  2  AAA_21           AAA domain, putative AbiEii toxin, Type IV T
      0.057   13.0   0.0        5.1    6.6   0.0    3.2  3  DUF927           Domain of unknown function (DUF927)
      0.058   13.1   0.3        2.2    8.0   0.0    3.5  2  PRK              Phosphoribulokinase / Uridine kinase family
      0.058   13.2  10.0        7.3    6.3   0.1    5.9  6  ATP_bind_1       Conserved hypothetical ATP binding protein
       0.08   12.8   9.4        1.2    9.1   0.0    5.1  4  NTPase_1         NTPase
      0.094   12.4   0.0         41    3.7   0.0    4.0  4  ATP-synt_ab      ATP synthase alpha/beta family, nucleotide-b
       0.13   11.8   5.5        2.3    7.7   0.0    4.6  5  FeoB_N           Ferrous iron transport protein B
       0.15   11.4   2.0         26    4.0   0.1    3.7  3  Septin           Septin
       0.15   12.1   2.2        6.6    6.8   0.0    3.2  2  tRNA_lig_kinase  tRNA ligase kinase domain
        1.4    8.4   8.9         25    4.4   0.1    5.1  5  cobW             CobW/HypB/UreG, nucleotide-binding domain


Domain annotation for each model (and alignments):
>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.8   0.0   7.6e-22   2.2e-19       1     123 [.     292     413 ..     292     424 .. 0.94
   2 !   30.4   0.0   1.1e-09   3.2e-07       1      47 [.     628     674 ..     628     698 .. 0.89
   3 !   32.5   0.0   2.5e-10   7.1e-08      52     138 .]     790     879 ..     778     879 .. 0.85
   4 !   78.8   0.0   1.3e-24   3.7e-22       2     138 .]    1064    1199 ..    1063    1199 .. 0.94
   5 !   22.2   0.0     4e-07   0.00011       1      46 [.    1353    1398 ..    1353    1411 .. 0.90
   6 !   42.9   0.0   1.6e-13   4.7e-11      38     138 .]    1452    1556 ..    1439    1556 .. 0.88
   7 !   70.9   0.0   3.5e-22   9.9e-20       2     138 .]    1738    1876 ..    1737    1876 .. 0.92
   8 !   25.2   0.0   4.7e-08   1.3e-05       2      57 ..    2046    2099 ..    2045    2114 .. 0.85
   9 !   32.3   0.0   2.9e-10   8.2e-08      49     134 ..    2181    2265 ..    2169    2269 .. 0.78

  Alignments for each domain:
  == domain 1  score: 69.8 bits;  conditional E-value: 7.6e-22
                 EEEEE--SSSSHHHHHHHGGGGB..S--EEEEE--TT--HHHHH--B--...........--------G-SEEEEESGGG--HHHHHHHHHHHHSSEEE CS
       AAA_5   1 dvlLvGppGtgKselaerlaaal..nreveyvqltrdtteedlkgrreik..ngttslvdsplvraaregeilvlDEveraesevlnsLlslleerrll 95 
                 ++lLvG p +gK++l+  +a+ +  + ++++  l+++t ++ l+g + ++   gt s+++++l++aa+eg+ +++++++ra+sev++ +l+++e+ +l 
  EEA22601.1 292 PLLLVGLPNSGKTSLVNDIAKIMgqGPSMVTLHLNEQTDAKSLLGMYATSslTGTFSWQPGVLTKAAKEGRWILIEDLDRAPSEVIGLMLPVIEKGELI 390
                 589********************888888999999**************9************************************************* PP

                 ..-SSSEEE---......-EEEEEESS- CS
       AAA_5  96 leeggelvkaknddllerfrviatanpl 123
                 +++++e++k++       fr+iat+ + 
  EEA22601.1 391 IPSRKERIKCADG-----FRIIATMKSS 413
                 **********985.....*******875 PP

  == domain 2  score: 30.4 bits;  conditional E-value: 1.1e-09
                 EEEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B-- CS
       AAA_5   1 dvlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrrei 47 
                 +vlLvG++G+gK+ ++++la ++++++++v+l+++ +++dl+g+ ++
  EEA22601.1 628 PVLLVGETGIGKTAVIQQLANLTCQKLTVVNLSQQSESTDLLGGFRP 674
                 59*****************************************9985 PP

  == domain 3  score: 32.5 bits;  conditional E-value: 2.5e-10
                 .....--------G-SEEEEESGGG--HHHHHHHHHHHHSSEEE..-SSSEEE---............-EEEEEESS--..-TT-TTHHHHTT- CS
       AAA_5  52 tslvdsplvraaregeilvlDEveraesevlnsLlslleerrllleeggelvkaknddller......frviatanpld.rslnelspalrsRf 138
                  ++v++++vra r+ge ++lDE++ a +++l+   sll++    l++    +  + +    r      fr+++++np+   ++ +l p lrsRf
  EEA22601.1 790 FAFVQGKIVRALRNGEWVLLDEINLATPDILENIASLLHHGDEGLPSVLLSEAGDVE----RvyghpdFRIFGAMNPATdAGKRDLAPGLRSRF 879
                 5799*************************************9998775433333322....1233567***********9999**********9 PP

  == domain 4  score: 78.8 bits;  conditional E-value: 1.3e-24
                  EEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--..........--------G-SEEEEESGGG--HHHHHHHHHHHHS.SEEE. CS
       AAA_5    2 vlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreik.ngttslvdsplvraaregeilvlDEveraesevlnsLlsllee.rrlll 96  
                  +lL+Gp+ +gK++++e+la++ +++++ +++++ t  ++ +g++  + +g  ++++++lv+a r+g  +vlDE++ a+s+vl++L++ll++ r+l l
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAKVSGNKFVRINNHEHTDLQEYLGSYVSTdDGSLKYQEGVLVEALRNGYWIVLDELNLAPSDVLEALNRLLDDnRELFL 1160
                  89******************************************9889*****************************************87255667 PP

                  .-SSSEEE---......-EEEEEESS--...-TT-TTHHHHTT- CS
       AAA_5   97 eeggelvkaknddllerfrviatanpld..rslnelspalrsRf 138 
                  +e +e+++  ++     f+++at np+   ++++ ls a+r Rf
  EEA22601.1 1161 PETQEVIQPHPN-----FMLFATQNPAGlyGGRKVLSRAFRNRF 1199
                  777777877777.....************9*************9 PP

  == domain 5  score: 22.2 bits;  conditional E-value: 4e-07
                  EEEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B- CS
       AAA_5    1 dvlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrre 46  
                  +vlLvG++G+gK+++ + +a+ +++e+ +v+ + ++++ d++g  +
  EEA22601.1 1353 PVLLVGETGCGKTQICQAVAEIYGKEMYIVNAHVNLETGDIVGAQR 1398
                  59***************************************99766 PP

  == domain 6  score: 42.9 bits;  conditional E-value: 1.6e-13
                  HHHHH--B--.............--------G-SEEEEESGGG--HHHHHHHHHHHHSSEEE..-SSSEEE---.......-EEEEEESS--..-TT CS
       AAA_5   38 eedlkgrreik....ngttslvdsplvraaregeilvlDEveraesevlnsLlslleerrllleeggelvkaknddller.frviatanpld.rsln 128 
                  +++l+ r++++    +   +++d++l +a+++g+ ++lDEv  a+++vl++L+s+le  r ll   ++ ++      +++  +++ t+np   +++ 
  EEA22601.1 1452 PSELLHRIKTNitrsQALFEWSDGSLITAMKTGQYFLLDEVSLADDSVLERLNSVLEPHRSLLLAEKGPIDSLV--VAQDgYQFLSTMNPGGdYGKR 1546
                  6777777777777778889**************************************99999999998886654..44557**************** PP

                  -TTHHHHTT- CS
       AAA_5  129 elspalrsRf 138 
                  els+alr R+
  EEA22601.1 1547 ELSAALRNRM 1556
                  ********97 PP

  == domain 7  score: 70.9 bits;  conditional E-value: 3.5e-22
                  EEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--.............--------G-SEEEEESGGG--HHHHHHHHHHHHSSE. CS
       AAA_5    2 vlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreik....ngttslvdsplvraaregeilvlDEveraesevlnsLlslleerr. 93  
                  +lL G pG+gK++l+ +la+al+++++ ++l+++t  +dl+g+  +      g+ +++d p+ +a+++g+ ++lDE + a+++vl+ L+s l++r+ 
  EEA22601.1 1738 ILLEGSPGVGKTTLVASLARALGKPLTRINLSDQTDLTDLFGSDVPVeggdAGQFAWRDAPFLQAMQKGDWVLLDEMNLASQSVLEGLNSCLDHRQq 1834
                  89****************************************9766669999******************************************972 PP

                  EE..-SSSEEE---......-EEEEEESS--...-TT-TTHHHHTT- CS
       AAA_5   94 llleeggelvkaknddllerfrviatanpld..rslnelspalrsRf 138 
                  ++++e+++  k  +d     f ++a+ np +  ++++ l ++++ Rf
  EEA22601.1 1835 VYVAELDQTFKRHPD-----FVLFAAQNPHHqgGGRKGLPASFVNRF 1876
                  566777777777665.....***********9999999999999998 PP

  == domain 8  score: 25.2 bits;  conditional E-value: 4.7e-08
                  EEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--.........- CS
       AAA_5    2 vlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreikngttslvds 57  
                   +LvGp+G+gK++ ++ la+  ++e+++ +l++dt + dl+g+ e  + +++++ +
  EEA22601.1 2046 SILVGPSGCGKTTTIRTLASIQGAELVELALSADTDTMDLIGGFE--QIDYRRQTQ 2099
                  59****************************************999..344444444 PP

  == domain 9  score: 32.3 bits;  conditional E-value: 2.9e-10
                  ........--------G-SEEEEESGGG--HHHHHHHHHHHHSSEEE...-SSSEEE---.........-EEEEEESS--.-TT-TTHHH CS
       AAA_5   49 ngttslvdsplvraaregeilvlDEveraesevlnsLlslleerrll.leeggelvkakndd.ller..frviatanpldrslnelspal 134 
                  + + ++++++l++a++ g+ +vlD  + ++ +vl++L+sl+e + +l l+e +++ + ++         fr++ t+ p++++l+    a+
  EEA22601.1 2181 KVGFEWTEGALTEAIQLGHWVVLDNANLCNASVLDRLNSLMEPNGYLvLNEQRTEDGSARMIvP--HpnFRLFLTMDPRNGELS---RAM 2265
                  56789*************************************8766615566666666664333..267**********95544...455 PP

>> AAA_lid_7  Midasin AAA lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.3   0.0   1.5e-19   4.2e-17       1     106 []     445     557 ..     445     557 .. 0.96
   2 !   42.8   0.8   1.7e-13   4.9e-11       1     105 [.    1211    1304 ..    1211    1305 .. 0.97
   3 ?    6.6   0.0      0.03       8.5      16      84 ..    1585    1642 ..    1569    1677 .. 0.64
   4 !   46.4   0.0   1.3e-14   3.6e-12       1     106 []    1888    1987 ..    1888    1987 .. 0.92

  Alignments for each domain:
  == domain 1  score: 62.3 bits;  conditional E-value: 1.5e-19
   AAA_lid_7   1 eLeeilqskfpllasvadklievyeelrseqsssrsfs.gspreislRDLlkWcrRlsalldrsg......flspsvreeifleavdvFaaslstqedr 92 
                 e++++l +k+pll++ +++li++y++l s+ +ss  +  +++r+ +lRDL+k+c+Rl+++l r g      ++ +  ++eifl+ vd F   l++++  
  EEA22601.1 445 EVRQVLIEKYPLLSTRVPTLIDIYDRLCSAFHSSLAARsAQGRTPGLRDLIKLCNRLHKRLLRLGvttgneATPEGFQDEIFLDTVDAFIRYLPDRDFG 543
                 799*******************************65557*********************99999*****9999************************* PP

   AAA_lid_7  93 lrvaeviaehlgls 106
                 +r+ ++iae+l+ls
  EEA22601.1 544 HRLSSIIAEALQLS 557
                 ***********996 PP

  == domain 2  score: 42.8 bits;  conditional E-value: 1.7e-13
   AAA_lid_7    1 eLeeilqskfpllasvadklievyeelrseqsssrsfsgspreislRDLlkWcrRlsalldrsgflspsvreeifleavdvFaaslstqedrlrvae 97  
                  eLe il+++ +++ s+++++++vy++l+ +++s+r f  ++   +lRDL++W+ R +             re ++  +++++a++++++++r +v +
  EEA22601.1 1211 ELEYILKERTQIAPSFCSRIVSVYKKLSVLRQSTRLFEQKNSFATLRDLFRWALRQADD-----------RETLAINGFMLLAERVRNSAERGAVKK 1296
                  899****************************************************9888...........9************************** PP

   AAA_lid_7   98 viaehlgl 105 
                  vi++++++
  EEA22601.1 1297 VIEDVMKV 1304
                  ****9987 PP

  == domain 3  score: 6.6 bits;  conditional E-value: 0.03
   AAA_lid_7   16 vadklievyeelrseqsssrsfsgspreislRDLlkWcrRlsalldrsgflspsvreeifleavdvFaa 84  
                   +++++++ +  ++  +      +s  ++s+RDLl W + +++       + ++    i++ a +v+  
  EEA22601.1 1585 KTKAMLQFAKWFKQTFQG-----SSTSSLSIRDLLGWVEFINKC------PPSNPDFAIVQGAAMVYID 1642
                  444444444444444444.....59****************998......3345666677777777754 PP

  == domain 4  score: 46.4 bits;  conditional E-value: 1.3e-14
   AAA_lid_7    1 eLeeilqskf.pllasvadklievyeelrseqsssrsfs..gspreislRDLlkWcrRlsalldrsgflspsvreeifleavdvFaaslstqedrlr 94  
                  +L++i+++ f +++++ ++k++e++++l+ +  + r f+  g p+e++lRD+++W ++ ++          +v+     ++  ++ ++++t++dr+ 
  EEA22601.1 1888 DLNSICSKLFpRIPSDQTSKMVEFMSKLNWAIDHDREFAniGGPWELNLRDIIRWFQLSDRG---------NVHIPSGYFLENIISHRFRTEKDRSL 1975
                  9*********77**************************99*********************9.........4555555566689************* PP

   AAA_lid_7   95 vaeviaehlgls 106 
                  + +v+++ ++++
  EEA22601.1 1976 ISSVFEQSFKIP 1987
                  *********986 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.1   6.9e-05      0.02      11      78 ..     268     334 ..     262     341 .. 0.88
   2 !   21.1   0.1   6.1e-07   0.00017      13      76 ..     606     666 ..     595     670 .. 0.78
   3 !    9.7   0.0     0.002      0.56      22      62 ..    1050    1089 ..    1032    1144 .. 0.81
   4 !   27.3   0.0   7.6e-09   2.2e-06       6      65 ..    1324    1383 ..    1320    1390 .. 0.90
   5 !   12.8   0.0   0.00022     0.061      19      74 ..    1721    1773 ..    1708    1780 .. 0.83
   6 ?    1.6   0.0       0.6   1.7e+02     119     179 ..    1818    1882 ..    1803    1884 .. 0.84
   7 !    9.7   0.0     0.002      0.57      29      76 ..    2039    2083 ..    2034    2101 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 6.9e-05
       AAA_7  11 eilVptvdtvrysyllelllknkkpvllvGptGtGKtviikdllkkldkekylsltinfsaqtsanql 78 
                 + lV+t   + +   +   l ++kp+llvG   +GKt++++d+ k +  +  +++t+ ++ qt+a++l
  EEA22601.1 268 SSLVKTETVTNNLRSVANALLEQKPLLLVGLPNSGKTSLVNDIAKIMG-QGPSMVTLHLNEQTDAKSL 334
                 56788888888888888889999*********************9999.99999**********9987 PP

  == domain 2  score: 21.1 bits;  conditional E-value: 6.1e-07
       AAA_7  13 lVptvdtvrysyllelllknkkpvllvGptGtGKtviikdllkkldkekylsltinfsaqtsan 76 
                 + pt   +++   +   ++ + pvllvG+tG GKt++i++l +    +k+  +++n+s+q +++
  EEA22601.1 606 FAPTRAALKTMEQIAVAVQVSEPVLLVGETGIGKTAVIQQLANLTC-QKL--TVVNLSQQSEST 666
                 567888888888899999**********************776555.444..456666666665 PP

  == domain 3  score: 9.7 bits;  conditional E-value: 0.002
       AAA_7   22 ysyllelllknkkpvllvGptGtGKtviikdllkkldkeky 62  
                  ++ ll+   +++ p+ll Gpt +GKt++++ l  k++ +k+
  EEA22601.1 1050 LKNLLRASSTRRFPILLQGPTSSGKTSMVEYL-AKVSGNKF 1089
                  6778999999*****************99854.44554544 PP

  == domain 4  score: 27.3 bits;  conditional E-value: 7.6e-09
       AAA_7    6 eakfseilVptvdtvrysyllelllknkkpvllvGptGtGKtviikdllkkldkekylsl 65  
                  ++++s+ +V t    r+ +l++  l+n+ pvllvG+tG+GKt i++ + + + ke y+++
  EEA22601.1 1324 KTSLSQNIVWTKAMRRVFVLVSEALRNNEPVLLVGETGCGKTQICQAVAEIYGKEMYIVN 1383
                  788999*****************************************9999998887765 PP

  == domain 5  score: 12.8 bits;  conditional E-value: 0.00022
       AAA_7   19 tvrysyllelllknkkpvllvGptGtGKtviikdllkkldkekylsltinfsaqts 74  
                  t+ +s+ +   l+ +kp+ll G+ G+GKt+++ +l ++l       + in+s qt+
  EEA22601.1 1721 TIANSVRIARGLQTSKPILLEGSPGVGKTTLVASLARALG---KPLTRINLSDQTD 1773
                  67777778888999***********************999...4456778888876 PP

  == domain 6  score: 1.6 bits;  conditional E-value: 0.6
       AAA_7  119 aqppiellRqlldygg.wYdr.kklefkeikdvqlvaamgp..pgggrneitpRllrhfnvlait 179 
                  +q+ +e l  +ld++  +Y    + +fk+  d +l aa +p  +gggr+ +++ ++ +f+v+  +
  EEA22601.1 1818 SQSVLEGLNSCLDHRQqVYVAeLDQTFKRHPDFVLFAAQNPhhQGGGRKGLPASFVNRFTVVYAD 1882
                  7889999999999976589884467**************9844699*************998765 PP

  == domain 7  score: 9.7 bits;  conditional E-value: 0.002
       AAA_7   29 llknkkpvllvGptGtGKtviikdllkkldkekylsltinfsaqtsan 76  
                  ++++  p +lvGp+G+GKt++i++l +         + + +sa t+ +
  EEA22601.1 2039 CIERAWPSILVGPSGCGKTTTIRTLASIQG---AELVELALSADTDTM 2083
                  56778899**************99775444...555566666666655 PP

>> AAA_lid_5  Midasin AAA lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.7   0.0   6.5e-31   1.8e-28       1     104 [.     893     996 ..     893     998 .. 0.98

  Alignments for each domain:
  == domain 1  score: 98.7 bits;  conditional E-value: 6.5e-31
   AAA_lid_5   1 DLellvknyLkevsltdqalvtdvvefYlelkklaerkeltdgagqkphfSlRtlsraLsyartilklaglrralyeGfsmsFltqLdsesrkkvekli 99 
                 DL  l+++yL ++  +d +l +d++ +Yl+ kkl  +++ltdgagqkphfS+Rtl+r+L y+ +++  +glrra yeGf+msFlt L++es+k+v  li
  EEA22601.1 893 DLLGLIQTYLGNLVQSDLRLASDIASLYLATKKLTLENKLTDGAGQKPHFSIRTLVRTLVYITDHVHSYGLRRAAYEGFCMSFLTLLSQESEKLVVPLI 991
                 9999*********99999********************************************************************************* PP

   AAA_lid_5 100 rkill 104
                 +k+++
  EEA22601.1 992 EKHIF 996
                 **986 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.4   0.0    0.0047       1.3       1      35 [.     293     329 ..     293     377 .. 0.70
   2 !   13.0   0.0   0.00036       0.1       1      75 [.     629     698 ..     629     716 .. 0.74
   3 !   12.6   0.0   0.00048      0.14       1      35 [.    1064    1098 ..    1064    1184 .. 0.81
   4 !   15.9   0.0   4.6e-05     0.013       1      33 [.    1354    1386 ..    1354    1421 .. 0.86
   5 !   21.3   0.0     1e-06   0.00029       1      36 [.    1738    1773 ..    1738    1861 .. 0.70
   6 !   19.9   0.0   2.8e-06   0.00078       2      96 ..    2047    2160 ..    2046    2180 .. 0.67

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0047
                 EEEESSTTSSHHHHHHHHHHHHT..HEEEEEETTTCS CS
         AAA   1 vllyGppGtGKTllakavakelg..vefleisgsell 35 
                 +ll+G p  GKT+l++ +ak +g   +++++ + e +
  EEA22601.1 293 LLLVGLPNSGKTSLVNDIAKIMGqgPSMVTLHLNEQT 329
                 69*******************9644445555555444 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 0.00036
                 EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHH..T CS
         AAA   1 vllyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksr..s 75 
                 vll+G  G+GKT++++++a+ + +++  +++s+         + ++ + f+ +   +   i ++DE+ +l++s    
  EEA22601.1 629 VLLVGETGIGKTAVIQQLANLTCQKLTVVNLSQQS------ESTDLLGGFRPVNLRS-MAIPLLDEFNQLFESTfsA 698
                 79*******************98888888888777......6677777777776665.6788888888888888432 PP

  == domain 3  score: 12.6 bits;  conditional E-value: 0.00048
                  EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCS CS
         AAA    1 vllyGppGtGKTllakavakelgvefleisgsell 35  
                  +ll Gp   GKT++++ +ak +g +f++i+ +e +
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAKVSGNKFVRINNHEHT 1098
                  699***************************99988 PP

  == domain 4  score: 15.9 bits;  conditional E-value: 4.6e-05
                  EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTT CS
         AAA    1 vllyGppGtGKTllakavakelgvefleisgse 33  
                  vll+G  G+GKT +++ava+  g e++ ++++ 
  EEA22601.1 1354 VLLVGETGCGKTQICQAVAEIYGKEMYIVNAHV 1386
                  79*******************998888888764 PP

  == domain 5  score: 21.3 bits;  conditional E-value: 1e-06
                  EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSS CS
         AAA    1 vllyGppGtGKTllakavakelgvefleisgsells 36  
                  +ll G pG+GKT+l+ ++a+ lg ++ +i++s+ ++
  EEA22601.1 1738 ILLEGSPGVGKTTLVASLARALGKPLTRINLSDQTD 1773
                  699****************************99873 PP

  == domain 6  score: 19.9 bits;  conditional E-value: 2.8e-06
                  EEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSS...........STTHHHHHHHHHHHHHHHTS.........TSEEEEEETGGGHHHHHTTCC CS
         AAA    2 llyGppGtGKTllakavakelgvefleisgsellsk...........yvgesekkirelfkeakeka.........kpsilfiDEidalaksrsgse 78  
                  +l+Gp G+GKT++++ +a+  g+e++e+ +s  ++            y  ++++  +++++ + ++          +  i  + Ei+++++++ + +
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLASIQGAELVELALSADTDTmdliggfeqidYRRQTQSLAKDVVNFIHRQIissvtsestSSGISDLLEIYRVCSHS-DIN 2142
                  79***************************9999855677777777775555555555555544333233333333333555566666666655.445 PP

                  CHHHHHHHHHHHHHHHHT CS
         AAA   79 seeeervvnqLlteldgv 96  
                  +e   +++n+L t +dg 
  EEA22601.1 2143 TETLANAINALQTRFDGP 2160
                  555556666666666655 PP

>> AAA_3  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.2   0.0    0.0037       1.1       2     111 ..     293     411 ..     292     424 .. 0.80
   2 ?    3.4   0.0      0.23        65       2      43 ..     629     670 ..     628     677 .. 0.88
   3 !   22.2   0.0   3.5e-07   9.9e-05       2     130 ..    1064    1200 ..    1063    1201 .. 0.81
   4 ?    5.3   0.0     0.059        17       2      46 ..    1354    1398 ..    1353    1424 .. 0.89
   5 !   42.8   0.0   1.5e-13   4.3e-11       2     130 ..    1738    1877 ..    1737    1878 .. 0.84
   6 ?    5.8   0.0     0.042        12       4      48 ..    2048    2093 ..    2046    2134 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0037
       AAA_3   2 vllegvPGlaktllvkalakaldlefkri..qftpdllPsdilGtevfeekekefefkkGpvfa.....nllladeinrappktqsalleameerqvtv 93 
                 +ll g+P  +kt lv+ +ak+++   + +   +        +lG+   ++ + +f+ ++G + +       +l ++++rap+ +   +l ++e  ++ +
  EEA22601.1 293 LLLVGLPNSGKTSLVNDIAKIMGQGPSMVtlHLNEQTDAKSLLGMYATSSLTGTFSWQPGVLTKaakegRWILIEDLDRAPSEVIGLMLPVIEKGELII 391
                 5899******************9876655115667777889*******************987622222479********************9888766 PP

       AAA_3  94 ..egethklpepflvlatqn 111
                   ++e+ k  + f ++at  
  EEA22601.1 392 psRKERIKCADGFRIIATMK 411
                 115566777899*****964 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.23
       AAA_3   2 vllegvPGlaktllvkalakaldlefkriqftpdllPsdilG 43 
                 vll g  G++kt ++++la+    +++ + +      +d+lG
  EEA22601.1 629 VLLVGETGIGKTAVIQQLANLTCQKLTVVNLSQQSESTDLLG 670
                 79999***************9999999998888777777776 PP

  == domain 3  score: 22.2 bits;  conditional E-value: 3.5e-07
       AAA_3    2 vllegvPGlaktllvkalakaldlefkriqftpdllPsdilGtevfeekekefefkkGpvfanl.....lladeinrappktqsalleameerqvtv 93  
                  +ll+g    +kt +v+ lak+ + +f ri         + lG+ v ++++ ++++++G ++  l     ++ de+n ap+ +  al   +++++  +
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAKVSGNKFVRINNHEHTDLQEYLGSYV-STDDGSLKYQEGVLVEALrngywIVLDELNLAPSDVLEALNRLLDDNRELF 1159
                  689999999*********************998888899999876.567899*******9987655566899************9988887766555 PP

       AAA_3   94 egethkl...pepflvlatqnPieqeGt.yplpeaqldrfl 130 
                    et+++   + +f+++atqnP    G    l  a  +rfl
  EEA22601.1 1160 LPETQEViqpHPNFMLFATQNPAGLYGGrKVLSRAFRNRFL 1200
                  5555554111557**********987651567888888886 PP

  == domain 4  score: 5.3 bits;  conditional E-value: 0.059
       AAA_3    2 vllegvPGlaktllvkalakaldlefkriqftpdllPsdilGtev 46  
                  vll g  G +kt++ +a+a++ + e+  +    +l  +di+G++ 
  EEA22601.1 1354 VLLVGETGCGKTQICQAVAEIYGKEMYIVNAHVNLETGDIVGAQR 1398
                  799999************************************875 PP

  == domain 5  score: 42.8 bits;  conditional E-value: 1.5e-13
       AAA_3    2 vllegvPGlaktllvkalakaldlefkriqftpdllPsdilGtevfee..kekefefkkGpvfanl.....lladeinrappktqsalleameerq. 90  
                  +lleg PG++kt+lv +la+al+  ++ri +      +d+ G++v  e  ++ +f  +  p ++ +     +l de+n a+  +   l  +++ rq 
  EEA22601.1 1738 ILLEGSPGVGKTTLVASLARALGKPLTRINLSDQTDLTDLFGSDVPVEggDAGQFAWRDAPFLQAMqkgdwVLLDEMNLASQSVLEGLNSCLDHRQq 1834
                  79******************************99999*****998766225599*******99755444449**********999888777765543 PP

       AAA_3   91 ..vtvegethklpepflvlatqnPieqeGt.yplpeaqldrfl 130 
                    v+  ++t+k +  f+++a+qnP +q G    lp + ++rf 
  EEA22601.1 1835 vyVAELDQTFKRHPDFVLFAAQNPHHQGGGrKGLPASFVNRFT 1877
                  22667789999999***********998761569*99999996 PP

  == domain 6  score: 5.8 bits;  conditional E-value: 0.042
       AAA_3    4 legvPGlaktllvkalakaldlefkriqftpdllPsdilGt.evfe 48  
                  l g  G +kt+++++la++ ++e+  + + +d    d++G  e ++
  EEA22601.1 2048 LVGPSGCGKTTTIRTLASIQGAELVELALSADTDTMDLIGGfEQID 2093
                  66788********************************998424444 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   0.0     0.014       3.9      14      50 ..     282     316 ..     272     346 .. 0.70
   2 !   18.5   0.1   7.3e-06    0.0021      25     164 ..     627     832 ..     610     839 .. 0.54
   3 !   12.5   0.1   0.00051      0.15      12      85 ..    1050    1119 ..    1047    1165 .. 0.66
   4 !   23.8   0.1   1.7e-07   4.9e-05      15     158 ..    1343    1506 ..    1334    1525 .. 0.69
   5 !   15.9   0.0   4.6e-05     0.013      25      51 ..    1736    1762 ..    1721    1838 .. 0.78
   6 !   14.7   0.0   0.00011     0.031      28      92 ..    2047    2116 ..    2041    2225 .. 0.56

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.014
      AAA_16  14 salervrsgrpelvllsGesGvGKsslvrellralek 50 
                 s+ +++ ++    +ll+G + +GK+slv+ +++ + +
  EEA22601.1 282 SVANALLEQ--KPLLLVGLPNSGKTSLVNDIAKIMGQ 316
                 333344444..669*****************975443 PP

  == domain 2  score: 18.5 bits;  conditional E-value: 7.3e-06
      AAA_16  25 elvllsGesGvGKsslvrellralekdggif.lrgkcdql............esaipysa.laqalareellrqllde............aesaeleaw 97 
                 e vll+Ge G+GK++++++l++  +++  ++ l+++ ++             ++aip++  + q++ + + + + +++                     
  EEA22601.1 627 EPVLLVGETGIGKTAVIQQLANLTCQKLTVVnLSQQSESTdllggfrpvnlrSMAIPLLDeFNQLF-E-STFSAKKNQkflssvtkslktG-------- 715
                 77*******************877777233333333333222222222233333355544344444.2.3333333332444443332220........ PP

      AAA_16  98 rekleeala.............................................................avpelagaeasrllellkrllallsrder 135
                         +                                                             ++++ +g+++ +++ +  ++++ l+++e 
  EEA22601.1 716 --------NwprlvnlwheavrmadsvfrvpkeseqnseeqpakkrkldspkytalrdkwegfkiqlsdfEAQASRGDSKFAFAFVQGKIVRALRNGEW 806
                 ........1344444444455555666666666666555555555555566677777777777776666555555555555555555555566666444 PP

      AAA_16 136 plvlvlDdlqwadeaslqllaaLlrlles 164
                    ++lD++  a ++ l+ +a+Ll+ ++ 
  EEA22601.1 807 ---VLLDEINLATPDILENIASLLHHGDE 832
                 ...77777777777777777777777665 PP

  == domain 3  score: 12.5 bits;  conditional E-value: 0.00051
      AAA_16   12 LlsalervrsgrpelvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipysa.laqalareellrql 85  
                  L+++l++ ++ r   +ll G+  +GK+s+v+ l++ ++++   f+r ++++++   +y+  ++++ +  +l  q+
  EEA22601.1 1050 LKNLLRASSTRRF-PILLQGPTSSGKTSMVEYLAK-VSGN--KFVRINNHEHTDLQEYLGsYVSTDDG-SLKYQE 1119
                  7889987777775.788****************96.5555..38888888875556776555555544.444444 PP

  == domain 4  score: 23.8 bits;  conditional E-value: 1.7e-07
      AAA_16   15 alervrsgrpelvllsGesGvGKsslvrellralekd....ggiflrgkcdqlesaipysalaqalareellrqlldeaesaeleawrekleeala. 106 
                  +++ + ++  e vll+Ge G+GK+ + +++++ + k+    ++++  ++ d  ++++p+    +a++r +l+ +l++  ++ +++a  ++  ++l  
  EEA22601.1 1343 LVSEALRNN-EPVLLVGETGCGKTQICQAVAEIYGKEmyivNAHVNLETGDIVGAQRPL-RNRSAIER-QLCDDLASVIST-LPDAEIDQSSKSLDn 1435
                  555555555.78*******************9999996666566666666666666775.67788845.999999999333.333333334444444 PP

      AAA_16  107 ...avpelagaeasrllellkrll.allsrder...............plvlvlDdlqwadeaslqllaaL 158 
                     a ++l+++  + +  +l + +   ++r +                  +++lD++  ad++ l+ l + 
  EEA22601.1 1436 lkaAFAQLTPEMLETVPSELLHRIkTNITRSQAlfewsdgslitamktGQYFLLDEVSLADDSVLERLNSV 1506
                  55577777777777777777777755555534477777778888887668888888888888776665554 PP

  == domain 5  score: 15.9 bits;  conditional E-value: 4.6e-05
      AAA_16   25 elvllsGesGvGKsslvrellralekd 51  
                    +ll G +GvGK++lv +l+ral k 
  EEA22601.1 1736 KPILLEGSPGVGKTTLVASLARALGKP 1762
                  789*******************99988 PP

  == domain 6  score: 14.7 bits;  conditional E-value: 0.00011
      AAA_16   28 llsGesGvGKsslvrellralekdggiflrgkcdqlesa.......ipysalaqalareellrqlldeaesa 92  
                  +l+G+sG+GK++ +r+l+ ++++++ + l+  +d  +++       i y   +q la+ ++++ ++++  s+
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLA-SIQGAELVELALSADTDTMDliggfeqIDYRRQTQSLAK-DVVNFIHRQIISS 2116
                  699***************.899987665666666665564455555555555555533.5555555552222 PP

>> Dynein_heavy  Dynein heavy chain region D6 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.0      0.77   2.2e+02      47      68 ..     353     374 ..     338     413 .. 0.80
   2 ?   -0.0   0.1       3.2   9.1e+02       4      41 ..     627     664 ..     624     668 .. 0.84
   3 !    8.9   0.0    0.0053       1.5      47      98 ..     796     864 ..     780     876 .. 0.77
   4 !   15.5   0.0   4.9e-05     0.014      17      97 ..    1075    1182 ..    1059    1195 .. 0.73
   5 ?    0.0   0.0       3.1   8.8e+02      47      78 ..    1476    1508 ..    1442    1520 .. 0.82
   6 !   10.8   0.0    0.0013      0.38      50      98 ..    1801    1860 ..    1783    1883 .. 0.80
   7 !   26.6   0.0   1.8e-08   5.1e-06      45     111 ..    2188    2272 ..    2161    2277 .. 0.80

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.77
                   HHHHHHHHT-EEEEE-GGG-CC CS
  Dynein_heavy  47 alekaakegsWvlLqNchlaps 68 
                   +l+kaakeg+W+l+++   aps
    EEA22601.1 353 VLTKAAKEGRWILIEDLDRAPS 374
                   6899***********9988766 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 3.2
                   S-EEEEE-TT--THHHHHHHHHHT.T--EEEEETTSHHH CS
  Dynein_heavy   4 tPvlfilspgadptesleklakkl.kklvksvslGqgqe 41 
                    Pvl++ ++g+  t+ +++la+ + +kl + v l q++e
    EEA22601.1 627 EPVLLVGETGIGKTAVIQQLANLTcQKL-TVVNLSQQSE 664
                   79********************662555.9999999877 PP

  == domain 3  score: 8.9 bits;  conditional E-value: 0.0053
                   HHHHHHHHT-EEEEE-GGG-.CCCHHHHHHH.......................HHTT-EEEEEEES-T CS
  Dynein_heavy  47 alekaakegsWvlLqNchla.pswlkeLekileel................eeklhssfRlwltsepsp 98 
                    + +a ++g+WvlL ++ la p+ l++++++l++                 +   h++fR++  ++p++
    EEA22601.1 796 KIVRALRNGEWVLLDEINLAtPDILENIASLLHHGdeglpsvllseagdveRVYGHPDFRIFGAMNPAT 864
                   68899***************7788888888865334555555666666665555678999987777765 PP

  == domain 4  score: 15.5 bits;  conditional E-value: 4.9e-05
                    HHHHHHHHHHT................T--EEEEETTSHHHHHHHHHHHHHHHHT-EEEEE-GGG-CC.CHHHHHHH.................H CS
  Dynein_heavy   17 tesleklakkl................kklvksvslGqgqeeeaekalekaakegsWvlLqNchlaps.wlkeLekileel..........eekl 84  
                    t+ +e lak                  + l ++vs  +g+ +  e +l +a ++g W++L +  laps  l+ L+++l++             + 
    EEA22601.1 1075 TSMVEYLAKVSgnkfvrinnhehtdlqEYLGSYVSTDDGSLKYQEGVLVEALRNGYWIVLDELNLAPSdVLEALNRLLDDNrelflpetqeVIQP 1169
                    55555555533334455544444444333557899999****************************651699*****886667788887554456 PP

                    HTT-EEEEEEES- CS
  Dynein_heavy   85 hssfRlwltseps 97  
                    h++f l+ t +p+
    EEA22601.1 1170 HPNFMLFATQNPA 1182
                    88*****999886 PP

  == domain 5  score: 0.0 bits;  conditional E-value: 3.1
                    HHHHHHHHT-EEEEE-GGG-.CCCHHHHHHH.. CS
  Dynein_heavy   47 alekaakegsWvlLqNchla.pswlkeLekile 78  
                     l +a+k+g++ lL ++ la  s l++L+++le
    EEA22601.1 1476 SLITAMKTGQYFLLDEVSLAdDSVLERLNSVLE 1508
                    6779****************7778999999987 PP

  == domain 6  score: 10.8 bits;  conditional E-value: 0.0013
                    HHHHHT-EEEEE-GGG-.CCCHHHHHHH.................HHTT-EEEEEEES-T CS
  Dynein_heavy   50 kaakegsWvlLqNchla.pswlkeLekileel..........eeklhssfRlwltsepsp 98  
                    +a+++g+WvlL ++ la +s l+ L++ l++           + k h++f l+   +p++
    EEA22601.1 1801 QAMQKGDWVLLDEMNLAsQSVLEGLNSCLDHRqqvyvaeldqTFKRHPDFVLFAAQNPHH 1860
                    89***************777899*****77545677777776666789999999999987 PP

  == domain 7  score: 26.6 bits;  conditional E-value: 1.8e-08
                    HHHHHHHHHHT-EEEEE-GGG-.CCCHHHHHHH.......................HHTT-EEEEEEES-TT.S-HHHHHTSEEE CS
  Dynein_heavy   45 ekalekaakegsWvlLqNchla.pswlkeLekileel................eeklhssfRlwltsepspk.fPislLqssikv 111 
                    e al++a++ g+Wv+L N  l+ +s l++L++++e                      h++fRl+lt++p +  +  ++ ++s+ v
    EEA22601.1 2188 EGALTEAIQLGHWVVLDNANLCnASVLDRLNSLMEPNgylvlneqrtedgsarMIVPHPNFRLFLTMDPRNGeLSRAMRNRSVEV 2272
                    6799******************888899*****77545677776677777765555688**********9954888888777766 PP

>> AAA_6  Hydrolytic ATP binding site of dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.0     0.091        26      10      84 ..     268     344 ..     264     349 .. 0.84
   2 !    8.8   0.0    0.0025      0.71      24     103 ..     618     698 ..     598     717 .. 0.79
   3 ?    5.7   0.0     0.022       6.3      83     170 ..     802     890 ..     787     932 .. 0.89
   4 !   12.0   0.0   0.00026     0.073       9      73 ..    1037    1102 ..    1034    1193 .. 0.85
   5 !   12.3   0.0   0.00021      0.06       8      70 ..    1327    1389 ..    1325    1395 .. 0.93
   6 !    8.5   0.0    0.0031      0.87      34      73 ..    1737    1776 ..    1718    1780 .. 0.85
   7 ?    6.1   0.0     0.016       4.6      35      71 ..    2046    2082 ..    2034    2118 .. 0.85
   8 ?   -2.4   0.0       6.1   1.7e+03      68     143 ..    2181    2256 ..    2161    2262 .. 0.69

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.091
       AAA_6  10 erLviTpltdrcyltltqAlklklggapaGpagtGKtEtvkdLakalak..qvvvfncsdqldykslgkifkGlaqs 84 
                 + Lv T       +++++Al  +    + G    GKt  v d+ak +++   +v ++ ++q d+ksl  +++  + +
  EEA22601.1 268 SSLVKTETVTNNLRSVANALLEQKPLLLVGLPNSGKTSLVNDIAKIMGQgpSMVTLHLNEQTDAKSLLGMYATSSLT 344
                 57899998888999999999999999999******************984468889999*****9998888755555 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.0025
       AAA_6  24 tltqAlklklggapaGpagtGKtEtvkdLakalakqvvvfncsdqldykslgkifkGla.qsGaWgCfdeFnrielevLSv 103
                  ++ A++++    + G +g GKt  +++La+   + ++v+n s+q + + l   f+ +  +s a   +deFn++  + +S+
  EEA22601.1 618 QIAVAVQVSEPVLLVGETGIGKTAVIQQLANLTCQKLTVVNLSQQSESTDLLGGFRPVNlRSMAIPLLDEFNQLFESTFSA 698
                 566677778888899*******************************99999888888752667778899999998877776 PP

  == domain 3  score: 5.7 bits;  conditional E-value: 0.022
       AAA_6  83 qsGaWgCfdeFnrielevLSvvaqqiktiqqalkekkkkfvfegkeiklnksvgifitmnp.gyagrteLPdnLkalfRpvammvPdle 170
                 + G W+ +de+n  + ++L  +a+ ++   + l + + +   + +++  +++++if  mnp + ag+ +L   L++ f ++ +  Pd++
  EEA22601.1 802 RNGEWVLLDEINLATPDILENIASLLHHGDEGLPSVLLSEAGDVERVYGHPDFRIFGAMNPaTDAGKRDLAPGLRSRFTEIYVHSPDVD 890
                 579************************999999999999888999999*************5579**********************86 PP

  == domain 4  score: 12.0 bits;  conditional E-value: 0.00026
       AAA_6    9 serLviTpltdrcyltltqAlklklgg.apaGpagtGKtEtvkdLakalakqvvvfncsdqldyks 73  
                  + + +iTp  ++    l++A +++     ++Gp+  GKt  v  Lak  ++ +v +n +++ d + 
  EEA22601.1 1037 QPHYIITPFIEKNLKNLLRASSTRRFPiLLQGPTSSGKTSMVEYLAKVSGNKFVRINNHEHTDLQE 1102
                  56789***************99987761689***************************99999865 PP

  == domain 5  score: 12.3 bits;  conditional E-value: 0.00021
       AAA_6    8 nserLviTpltdrcyltltqAlklklggapaGpagtGKtEtvkdLakalakqvvvfncsdqld 70  
                  +s+++v T    r+++ + +Al+ +    + G +g GKt  ++ +a+  +k ++++n + +l+
  EEA22601.1 1327 LSQNIVWTKAMRRVFVLVSEALRNNEPVLLVGETGCGKTQICQAVAEIYGKEMYIVNAHVNLE 1389
                  5789*****************************************************987765 PP

  == domain 6  score: 8.5 bits;  conditional E-value: 0.0031
       AAA_6   34 ggapaGpagtGKtEtvkdLakalakqvvvfncsdqldyks 73  
                     ++G+ g GKt  v +La+al+k ++ +n sdq d + 
  EEA22601.1 1737 PILLEGSPGVGKTTLVASLARALGKPLTRINLSDQTDLTD 1776
                  556799*****************************99865 PP

  == domain 7  score: 6.1 bits;  conditional E-value: 0.016
       AAA_6   35 gapaGpagtGKtEtvkdLakalakqvvvfncsdqldy 71  
                  + + Gp+g GKt t++ La+  +  +v +  s + d+
  EEA22601.1 2046 SILVGPSGCGKTTTIRTLASIQGAELVELALSADTDT 2082
                  5678****************99998888777766665 PP

  == domain 8  score: -2.4 bits;  conditional E-value: 6.1
       AAA_6   68 qldykslgkifkGlaqsGaWgCfdeFnrielevLSvvaqqiktiqqalkekkkkfvfegkeiklnksvgifitmnp 143 
                  ++ ++  +  ++  +q G W+ +d+ n  +++vL    + ++     + +++++   + + i  ++++++f+tm p
  EEA22601.1 2181 KVGFEWTEGALTEAIQLGHWVVLDNANLCNASVLDRLNSLMEPNGYLVLNEQRTEDGSARMIVPHPNFRLFLTMDP 2256
                  5555555566666789******************988887776666666666666666666666777777777776 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0      0.37     1e+02       5      60 ..     290     338 ..     287     348 .. 0.85
   2 !   13.5   0.0   0.00023     0.066       8      57 ..     629     669 ..     626     709 .. 0.92
   3 ?    1.7   0.0         1     3e+02       8      79 ..    1064    1123 ..    1058    1164 .. 0.68
   4 !    9.1   0.0    0.0053       1.5       8      32 ..    1354    1378 ..    1348    1462 .. 0.83
   5 !   12.9   0.0   0.00035     0.099       5      57 ..    1735    1778 ..    1730    1835 .. 0.88
   6 !   13.9   0.0   0.00017     0.049       9      57 ..    2047    2086 ..    2041    2118 .. 0.83

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.37
      AAA_22   5 agilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrel 60 
                 ++ l+++G + +GKT l++ +++   +       +p+ v+  l+++t+ k+ll + 
  EEA22601.1 290 QKPLLLVGLPNSGKTSLVNDIAKIMGQ-------GPSMVTLHLNEQTDAKSLLGMY 338
                 67899***************9999865.......8999999999999888887765 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 0.00023
      AAA_22   8 lvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdll 57 
                 ++++Ge+G+GKT ++++l++           + ++  v+l+++++s+dll
  EEA22601.1 629 VLLVGETGIGKTAVIQQLANLT---------CQKLTVVNLSQQSESTDLL 669
                 589******************9.........8889999999999888886 PP

  == domain 3  score: 1.7 bits;  conditional E-value: 1
      AAA_22    8 lvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelkaerlsseell 79  
                  +++ G++ +GKT  ++ l++           + ++v+++  + t++++ l   ++  + +lk+   ++  l+
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAKVS---------GNKFVRINNHEHTDLQEYLGSYVSTDDGSLKY---QEGVLV 1123
                  6888*********999999987.........88999999999888888877777766665555...333333 PP

  == domain 4  score: 9.1 bits;  conditional E-value: 0.0053
      AAA_22    8 lvvtGesGtGKTtllrrlleqldee 32  
                  ++++Ge+G+GKT  ++ ++e + +e
  EEA22601.1 1354 VLLVGETGCGKTQICQAVAEIYGKE 1378
                  789***************9988544 PP

  == domain 5  score: 12.9 bits;  conditional E-value: 0.00035
      AAA_22    5 agilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdll 57  
                   + +++ G +G+GKTtl++ l++ l         ++++ +++l+ +t+++dl+
  EEA22601.1 1735 SKPILLEGSPGVGKTTLVASLARAL---------GKPLTRINLSDQTDLTDLF 1778
                  5678999******************.........9************999986 PP

  == domain 6  score: 13.9 bits;  conditional E-value: 0.00017
      AAA_22    9 vvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdll 57  
                  +++G+sG+GKTt++r+l++           ++e+v+  l+++t+  dl 
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLASIQ---------GAELVELALSADTDTMDLI 2086
                  79****************998.........8888888888887666664 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0       0.3        87       3      25 ..     294     320 ..     293     367 .. 0.76
   2 ?    8.0   0.0     0.011       3.1       2      40 ..     629     671 ..     629     740 .. 0.73
   3 ?    6.8   0.0     0.024         7       2      83 ..    1064    1142 ..    1064    1160 .. 0.67
   4 ?    2.6   0.0      0.49   1.4e+02       2      31 ..    1354    1385 ..    1354    1450 .. 0.78
   5 !   16.1   0.0   3.4e-05    0.0096       2      45 ..    1738    1785 ..    1738    1860 .. 0.54
   6 !   14.9   0.0   7.9e-05     0.022       3      82 ..    2047    2210 ..    2046    2229 .. 0.65

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.3
      AAA_33   3 llvGlpGsGKstlaerllkklg....a 25 
                 llvGlp sGK+ l+  ++k  g    +
  EEA22601.1 294 LLVGLPNSGKTSLVNDIAKIMGqgpsM 320
                 79************9988766655563 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.011
      AAA_33   2 vllvGlpGsGKstlaerl....lkklgavllssdtlrrrlfgt 40 
                 vllvG  G GK+ ++++l    ++kl++v ls+ ++++ l g 
  EEA22601.1 629 VLLVGETGIGKTAVIQQLanltCQKLTVVNLSQQSESTDLLGG 671
                 799***************8878888889999999988877763 PP

  == domain 3  score: 6.8 bits;  conditional E-value: 0.024
      AAA_33    2 vllvGlpGsGKstlaerllkklg..avllssdtlrrrlfgtdqqsktdytrvldrlyqilnelarkalsagrnvildatnlsrr 83  
                  +ll G+  sGK+  +e l+k  g  +v+++  + ++ l +       +     d   + +++++ +al+ g+ ++ld  nl ++
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAKVSGnkFVRINNHE-HTDLQEYLGS---Y-VSTDDGSLKYQEGVLVEALRNGYWIVLDELNLAPS 1142
                  5789*******************9999999875.5555543222...2.22222233333566667777777777776666654 PP

  == domain 4  score: 2.6 bits;  conditional E-value: 0.49
      AAA_33    2 vllvGlpGsGKstlaerllkklg..avllssd 31  
                  vllvG  G+GK++  + +++  g  +++++  
  EEA22601.1 1354 VLLVGETGCGKTQICQAVAEIYGkeMYIVNAH 1385
                  799************99998777776666655 PP

  == domain 5  score: 16.1 bits;  conditional E-value: 3.4e-05
      AAA_33    2 vllvGlpGsGKstlaerllkklg..avllssdt..lrrrlfgtdqqsk 45  
                  +ll G pG+GK+tl+ +l+++lg   ++++  +   ++ lfg+d++ +
  EEA22601.1 1738 ILLEGSPGVGKTTLVASLARALGkpLTRINLSDqtDLTDLFGSDVPVE 1785
                  6899*******************9966655444334445555444432 PP

  == domain 6  score: 14.9 bits;  conditional E-value: 7.9e-05
      AAA_33    3 llvGlpGsGKstlaerllkklg...avl.lssdt............................................................... 32  
                  +lvG++G+GK+t ++ l+  +g   ++l ls dt                                                               
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLASIQGaelVELaLSADTdtmdliggfeqidyrrqtqslakdvvnfihrqiissvtsestssgisdlleiyrvcshsdint 2143
                  79****************9999554333466666888888888888888888888888888888888888888888887777777777777777777 PP

      AAA_33   33 .....................lrrrlfgtdqqsktdytrvldrlyqilnelarkalsagrnvildatnlsr 82  
                                       l +r+++  q+sk d  +v +   +++++ +++a + g  v+ld+ nl +
  EEA22601.1 2144 etlanainalqtrfdgptfnnLAQRCTALVQTSK-DAHKVGF---EWTEGALTEAIQLGHWVVLDNANLCN 2210
                  7777766654444444444433333333222222.2222333...35566677778888888888887766 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.3   0.0    0.0031      0.88       5     148 ..     273     417 ..     270     435 .. 0.79
   2 !   13.2   0.1   0.00019     0.055       8      47 ..     612     651 ..     607     669 .. 0.80
   3 !    9.4   0.0    0.0027      0.78      12     121 ..    1051    1156 ..    1043    1180 .. 0.80
   4 !   14.2   0.0   9.6e-05     0.027       5      44 ..    1334    1373 ..    1331    1394 .. 0.85
   5 ?    5.4   0.0     0.047        13      15      62 ..    1728    1772 ..    1716    1861 .. 0.63

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.0031
                      SHHHHHHHHHHHHHCTSSS-EEEECSTTSSHHHHHHHHHHHSTTTTS-EEEEETTTS-TTCHHHHHHE.BSSSSSTTTSS-BEHHHHHT.TTS. CS
  Sigma54_activat   5 sealkelleqikkvaktdlsvlitGesGtGKellaraiheaskrkekpfvavncaaipeelleseLFG.hekGaFtGAekekkGlfeka.dgG. 95 
                      +e++++ l++++++   + ++l++G   +GK+ l + i +    +  ++v++      e+  + +L G ++  + tG+ + + G + ka ++G 
       EEA22601.1 273 TETVTNNLRSVANALLEQKPLLLVGLPNSGKTSLVNDIAKIMG-QGPSMVTLHLN---EQTDAKSLLGmYATSSLTGTFSWQPGVLTKAaKEGr 362
                      556777788888899999********************98776.45557777654...4444455555278899**********9987634442 PP

                      EEEEETGGGS-HHHHHHHHHHHHHSEEESBTSSSEEE--..EEEEEEESS-HHHH CS
  Sigma54_activat  96 tlfLDeigelplelQekLlrvlqegevervGsskeikvd..vriiaatnedleea 148
                       ++++++ + p e+   +l v+++ge+     ++ ik+   +riia+ +++l+++
       EEA22601.1 363 WILIEDLDRAPSEVIGLMLPVIEKGELIIPSRKERIKCAdgFRIIATMKSSLNSK 417
                      7999**********************98777777666533489999999888876 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 0.00019
                      HHHHHHHHHHHCTSSS-EEEECSTTSSHHHHHHHHHHHST CS
  Sigma54_activat   8 lkelleqikkvaktdlsvlitGesGtGKellaraiheask 47 
                        +++eqi+ +++ + +vl++Ge+G GK+ + +++ + + 
       EEA22601.1 612 ALKTMEQIAVAVQVSEPVLLVGETGIGKTAVIQQLANLTC 651
                      5678999***********************9998877554 PP

  == domain 3  score: 9.4 bits;  conditional E-value: 0.0027
                       HHHHHHHCTSSS-EEEECSTTSSHHHHHHHHHHHSTTTTS-EEEEETTTS-TTCHHHHHHEBSSSSSTTTSS-BEHHHHHT..TTSEEEEET CS
  Sigma54_activat   12 leqikkvaktdlsvlitGesGtGKellaraiheaskrkekpfvavncaaipeelleseLFGhekGaFtGAekekkGlfeka..dgGtlfLDe 101 
                        + +++  + + ++l++G + +GK+ + + + + s    ++fv++n  + ++    +e  G    +  G+ k ++G + +a  +g  + LDe
       EEA22601.1 1051 KNLLRASSTRRFPILLQGPTSSGKTSMVEYLAKVSG---NKFVRINNHEHTD---LQEYLGSYVSTDDGSLKYQEGVLVEAlrNGYWIVLDE 1136
                       344455556669***************999987776...78****9876554...3566788888899999999*99877754556799*** PP

                       GGGS-HHHHHHHHHHHHHSE CS
  Sigma54_activat  102 igelplelQekLlrvlqege 121 
                       ++  p ++ e L r+l++++
       EEA22601.1 1137 LNLAPSDVLEALNRLLDDNR 1156
                       ********999999999865 PP

  == domain 4  score: 14.2 bits;  conditional E-value: 9.6e-05
                       SHHHHHHHHHHHHHCTSSS-EEEECSTTSSHHHHHHHHHH CS
  Sigma54_activat    5 sealkelleqikkvaktdlsvlitGesGtGKellaraihe 44  
                       ++a+++++  ++++ +++ +vl++Ge+G+GK+ + +a+ e
       EEA22601.1 1334 TKAMRRVFVLVSEALRNNEPVLLVGETGCGKTQICQAVAE 1373
                       578999****************************999876 PP

  == domain 5  score: 5.4 bits;  conditional E-value: 0.047
                       HHHHCTSSS-EEEECSTTSSHHHHHHHHHHHSTTTTS-EEEEETTTS- CS
  Sigma54_activat   15 ikkvaktdlsvlitGesGtGKellaraiheaskrkekpfvavncaaip 62  
                       i++  +t+ ++l++G  G+GK++l  ++ +a     kp+ ++n ++ +
       EEA22601.1 1728 IARGLQTSKPILLEGSPGVGKTTLVASLARAL---GKPLTRINLSDQT 1772
                       556678999************99887776544...4777778777654 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0      0.13        37       2      45 ..     290     332 ..     289     353 .. 0.83
   2 ?    4.3   0.0      0.13        37       3      44 ..     627     665 ..     625     711 .. 0.75
   3 !   16.3   0.0   2.6e-05    0.0073       4      92 ..    1063    1157 ..    1060    1163 .. 0.71
   4 ?    2.0   0.0      0.69     2e+02       2      27 ..    1351    1376 ..    1350    1411 .. 0.79
   5 !   15.0   0.0   6.7e-05     0.019       2      96 ..    1735    1836 ..    1734    1840 .. 0.69
   6 ?    5.8   0.0     0.047        13       6      43 ..    2047    2081 ..    2044    2113 .. 0.76

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.13
      AAA_14   2 rkilvitGaRrvGKTtllkqlikellvkkesilyinldderdkk 45 
                 +k+l+++G+  +GKT l+++++k    +  s++ + l++++d+k
  EEA22601.1 290 QKPLLLVGLPNSGKTSLVNDIAKIMG-QGPSMVTLHLNEQTDAK 332
                 6899*****************97666.77888888888777755 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.13
      AAA_14   3 kilvitGaRrvGKTtllkqlikellvkkesilyinldderdk 44 
                 ++++++G   +GKT +++ql++      ++   +nl +++++
  EEA22601.1 627 EPVLLVGETGIGKTAVIQQLANLTC---QKLTVVNLSQQSES 665
                 678999**************97666...88888888887763 PP

  == domain 3  score: 16.3 bits;  conditional E-value: 2.6e-05
      AAA_14    4 ilvitGaRrvGKTtllkqlikellvkkesilyinldderd.......kkladpe.......kllelileklke..ekktylflDEiqevpe.wekal 83  
                  +++++G+  +GKT +++ l+k +    ++++ in  +++d       +             k+ e +l    e  ++ ++++lDE   +p+ + +al
  EEA22601.1 1063 PILLQGPTSSGKTSMVEYLAKVSG---NKFVRINNHEHTDlqeylgsY-----VstddgslKYQEGVLV---EalRNGYWIVLDELNLAPSdVLEAL 1148
                  689*****************8888...999999988877743333321.....1112232333333333...14558999********974499*** PP

      AAA_14   84 kslvdegkn 92  
                  ++l+d++++
  EEA22601.1 1149 NRLLDDNRE 1157
                  *****9866 PP

  == domain 4  score: 2.0 bits;  conditional E-value: 0.69
      AAA_14    2 rkilvitGaRrvGKTtllkqlikell 27  
                  +++++++G   +GKT +++ +++ + 
  EEA22601.1 1351 NEPVLLVGETGCGKTQICQAVAEIYG 1376
                  7899**************99885544 PP

  == domain 5  score: 15.0 bits;  conditional E-value: 6.7e-05
      AAA_14    2 rkilvitGaRrvGKTtllkqlikellvkkesilyinldderd.........kkladpe.........kllelileklke..ekktylflDEiqevpe 78  
                  +k+++++G   vGKTtl+  l++ l    +    inl d++d                           +  +l    +  +k  +++lDE+  +++
  EEA22601.1 1735 SKPILLEGSPGVGKTTLVASLARALG---KPLTRINLSDQTDltdlfgsdvP-----VeggdagqfaWRDAPFL----QamQKGDWVLLDEMNLASQ 1819
                  6899******************9999...9*********9994444333330.....13332221112223333....13458999******98754 PP

      AAA_14   79 .wekalkslvdegknldvi 96  
                   + + l+s++d++++  v+
  EEA22601.1 1820 sVLEGLNSCLDHRQQ--VY 1836
                  378899999998844..44 PP

  == domain 6  score: 5.8 bits;  conditional E-value: 0.047
      AAA_14    6 vitGaRrvGKTtllkqlikellvkkesilyinldderd 43  
                  +++G+  +GKTt +++l++ +     + ++++l  ++d
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLASIQG---AELVELALSADTD 2081
                  899**************96555...6777776666555 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.0      0.42   1.2e+02       2      22 ..     294     314 ..     293     340 .. 0.84
   2 ?    2.2   0.0       0.9   2.6e+02       1      38 [.     629     669 ..     629     710 .. 0.75
   3 ?    7.8   0.0     0.016       4.7       1      41 [.    1064    1108 ..    1064    1178 .. 0.67
   4 ?    7.2   0.0     0.024       6.9       1      48 [.    1354    1402 ..    1354    1459 .. 0.72
   5 !   12.8   0.0   0.00044      0.13       1      27 [.    1738    1767 ..    1738    1835 .. 0.80
   6 !   10.1   0.0    0.0031      0.89       2      44 ..    2047    2087 ..    2047    2126 .. 0.74

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.42
      AAA_18   2 lltGtpGvGKttlakeLskrl 22 
                 ll G p +GKt+l + ++k +
  EEA22601.1 294 LLVGLPNSGKTSLVNDIAKIM 314
                 689************999976 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.9
      AAA_18   1 IlltGtpGvGKttlakeLskrlgf....gvnlrdvakengll 38 
                 +ll G  G GKt + + L++++ +    +vnl++     +ll
  EEA22601.1 629 VLLVGETGIGKTAVIQQLANLT-CqkltVVNLSQQSESTDLL 669
                 7899**************9985.5556766666555555555 PP

  == domain 3  score: 7.8 bits;  conditional E-value: 0.016
      AAA_18    1 IlltGtpGvGKttlakeLskrlgf.............gvnlrdvakenglllev 41  
                  Ill G+  +GKt++ ++L+k  g+                       ++l  +v
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAKVSGNkfvrinnhehtdlQ---------EYLGSYV 1108
                  899***************99876677775533333332.........3333322 PP

  == domain 4  score: 7.2 bits;  conditional E-value: 0.024
      AAA_18    1 IlltGtpGvGKttlakeLskrlgf...gvnlrdvakenglllevdpealde 48  
                  +ll G  G+GKt++++++++  g     vn   ++  ++++  + p   ++
  EEA22601.1 1354 VLLVGETGCGKTQICQAVAEIYGKemyIVNAHVNLETGDIVGAQRPL--RN 1402
                  7899**************88732244555555555555555555555..44 PP

  == domain 5  score: 12.8 bits;  conditional E-value: 0.00044
      AAA_18    1 IlltGtpGvGKttlakeLskrlgf...gvn 27  
                  Ill G pGvGKttl   L++ lg     +n
  EEA22601.1 1738 ILLEGSPGVGKTTLVASLARALGKpltRIN 1767
                  89******************9843455333 PP

  == domain 6  score: 10.1 bits;  conditional E-value: 0.0031
      AAA_18    2 lltGtpGvGKttlakeLskrlgfgvnlrdvakenglllevdpe 44  
                  +l G++G+GKtt  + L++    g +l ++a   ++ +++   
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLASIQ--GAELVELALSADTDTMDLIG 2087
                  689**************9998..88888888777777666655 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0       1.2   3.4e+02      16      57 ..     290     329 ..     280     365 .. 0.75
   2 ?    4.8   0.0     0.071        20      20      63 ..     628     670 ..     615     728 .. 0.76
   3 ?    3.4   0.0      0.19        53      20     114 ..    1063    1154 ..    1051    1160 .. 0.80
   4 !    8.1   0.0    0.0071         2      13     113 ..    1347    1508 ..    1342    1516 .. 0.61
   5 !   13.8   0.0   0.00012     0.035      20     114 ..    1737    1831 ..    1726    1838 .. 0.83
   6 !   10.2   0.0    0.0016      0.44      18      55 ..    2043    2080 ..    2037    2229 .. 0.75

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 1.2
      AAA_30  16 sgdrvavltGpAGtGKttalkalreaweaaggrviglAptgk 57 
                 ++    +l+G + +GKt +++ +++++ +    v +   +++
  EEA22601.1 290 QK--PLLLVGLPNSGKTSLVNDIAKIMGQGPSMVTLHLNEQT 329
                 33..5799*****************99987655555444444 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.071
      AAA_30  20 vavltGpAGtGKttalkalreaweaaggrviglAptgkaAkvLa 63 
                  ++l+G  G GKt ++++l+++  ++  +v+ l+ +++  + L+
  EEA22601.1 628 PVLLVGETGIGKTAVIQQLANLTCQK-LTVVNLSQQSESTDLLG 670
                 4799****************998866.68999998888877776 PP

  == domain 3  score: 3.4 bits;  conditional E-value: 0.19
      AAA_30   20 vavltGpAGtGKttalkalreaweaaggrviglAptgkaAkvLaeelgieastiakllkrlk...grarlepgtllivDEagmvdtkqlaallkaae 113 
                    +l+Gp  +GKt +++ l+++  ++    +    ++    +L+e lg   st +  lk ++     ++l++g  ++ DE  ++ ++ l+al + ++
  EEA22601.1 1063 PILLQGPTSSGKTSMVEYLAKVSGNKF---V--RINNHEHTDLQEYLGSYVSTDDGSLKYQEgvlV-EALRNGYWIVLDELNLAPSDVLEALNRLLD 1153
                  45789**********999999987664...3..335666679*******9***9999988888852.5788899*************9999998877 PP

      AAA_30  114 k 114 
                  +
  EEA22601.1 1154 D 1154
                  6 PP

  == domain 4  score: 8.1 bits;  conditional E-value: 0.0071
      AAA_30   13 lltsgdrvavltGpAGtGKttalkalreaweaag...........grviglAptgkaAkv.Laeelgi...eastiakllkrlk............. 81  
                  +l +++  ++l+G  G GKt + +a++e++ ++            g           A++ L++ + i    ++ +a+++++l              
  EEA22601.1 1347 ALRNNE-PVLLVGETGCGKTQICQAVAEIYGKEMyivnahvnletG-------DIVGAQRpLRNRSAIerqLCDDLASVISTLPdaeidqssksldn 1435
                  555554.7899********************997566633333332.......33444444444333322212222222222223334444444445 PP

      AAA_30   82 .........................................grarlepgtllivDEagmvdtkqlaallkaae 113 
                                                             +++++g+ ++ DE++++d + l++l + +e
  EEA22601.1 1436 lkaafaqltpemletvpsellhriktnitrsqalfewsdgsLITAMKTGQYFLLDEVSLADDSVLERLNSVLE 1508
                  5555556667777777777777777777788888888887733456777888888888888888888877665 PP

  == domain 5  score: 13.8 bits;  conditional E-value: 0.00012
      AAA_30   20 vavltGpAGtGKttalkalreaweaaggrviglAptgkaAkvLaeelgieastiakllkrlk...grarlepgtllivDEagmvdtkqlaallkaae 113 
                    +l+G +G GKtt++++l++a+ +   + i l+ +    +  + ++ +e+    ++  r +   +  ++++g+ ++ DE+ +++++ l+ l + ++
  EEA22601.1 1737 PILLEGSPGVGKTTLVASLARALGKP-LTRINLSDQTDLTDLFGSDVPVEGGDAGQFAWRDApflQ--AMQKGDWVLLDEMNLASQSVLEGLNSCLD 1830
                  4789******************9965.67789999**********************988876432..46667**************9999987776 PP

      AAA_30  114 k 114 
                  +
  EEA22601.1 1831 H 1831
                  6 PP

  == domain 6  score: 10.2 bits;  conditional E-value: 0.0016
      AAA_30   18 drvavltGpAGtGKttalkalreaweaaggrviglApt 55  
                  ++ ++l+Gp G GKtt++++l+ +  a+  ++++ A t
  EEA22601.1 2043 AWPSILVGPSGCGKTTTIRTLASIQGAELVELALSADT 2080
                  56689****************99988776555555544 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0      0.28        80       7      45 ..     280     316 ..     269     322 .. 0.70
   2 !    9.2   0.1    0.0039       1.1      12      42 ..     617     649 ..     600     658 .. 0.71
   3 ?    6.1   0.0     0.036        10      21      48 ..    1059    1092 ..    1043    1107 .. 0.71
   4 !    9.1   0.0    0.0042       1.2      16      45 ..    1346    1377 ..    1326    1384 .. 0.75
   5 !   12.6   0.0   0.00035       0.1      13      45 ..    1727    1761 ..    1716    1767 .. 0.75
   6 ?    2.9   0.0      0.37   1.1e+02      23      45 ..    2047    2069 ..    2026    2076 .. 0.83

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.28
                 HHHHHHHHHHCHTEEEEEEESTTSSHHHHHHHHHHHTT- CS
        TsaE   7 tealgkklakalgdvilLeGdLGaGKTtlvrglakalgv 45 
                 +++++++l +  ++ +lL G   +GKT lv  +ak +g 
  EEA22601.1 280 LRSVANALLE--QKPLLLVGLPNSGKTSLVNDIAKIMGQ 316
                 2333333333..667*******************99875 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.0039
                 HHHHHCH..TEEEEEEESTTSSHHHHHHHHHHH CS
        TsaE  12 kklakal..gdvilLeGdLGaGKTtlvrglaka 42 
                 +++a a+  ++ +lL G+ G GKT+ +++la+ 
  EEA22601.1 617 EQIAVAVqvSEPVLLVGETGIGKTAVIQQLANL 649
                 223222233556*****************9875 PP

  == domain 3  score: 6.1 bits;  conditional E-value: 0.036
                  E....EEEEESTTSSHHHHHHHHHHHTT--..-- CS
        TsaE   21 v....ilLeGdLGaGKTtlvrglakalgve..ev 48  
                  +    ilL+G+  +GKT +v  lak  g +  ++
  EEA22601.1 1059 TrrfpILLQGPTSSGKTSMVEYLAKVSGNKfvRI 1092
                  134569******************9988765555 PP

  == domain 4  score: 9.1 bits;  conditional E-value: 0.0042
                  HCH..TEEEEEEESTTSSHHHHHHHHHHHTT- CS
        TsaE   16 kal..gdvilLeGdLGaGKTtlvrglakalgv 45  
                  +al  ++ +lL G+ G+GKT++++++a+ +g 
  EEA22601.1 1346 EALrnNEPVLLVGETGCGKTQICQAVAEIYGK 1377
                  33333455******************998775 PP

  == domain 5  score: 12.6 bits;  conditional E-value: 0.00035
                  HHHHCH..TEEEEEEESTTSSHHHHHHHHHHHTT- CS
        TsaE   13 klakal..gdvilLeGdLGaGKTtlvrglakalgv 45  
                  ++a+ l  ++ ilLeG  G+GKTtlv +la+alg 
  EEA22601.1 1727 RIARGLqtSKPILLEGSPGVGKTTLVASLARALGK 1761
                  33443332566*********************985 PP

  == domain 6  score: 2.9 bits;  conditional E-value: 0.37
                  EEEESTTSSHHHHHHHHHHHTT- CS
        TsaE   23 lLeGdLGaGKTtlvrglakalgv 45  
                  +L G+ G+GKTt +r la+  g 
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLASIQGA 2069
                  799*************9987665 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.0   0.0       4.1   1.2e+03      10      36 ..     289     315 ..     280     339 .. 0.76
   2 !   11.0   0.0    0.0016      0.45       3      74 ..     618     695 ..     616     761 .. 0.69
   3 ?   -0.7   0.0       6.6   1.9e+03      16      37 ..    1066    1087 ..    1063    1117 .. 0.78
   4 !   12.2   0.0    0.0007       0.2       5      39 ..    1345    1379 ..    1343    1467 .. 0.78
   5 ?    5.9   0.0      0.06        17       8      42 ..    1732    1766 ..    1727    1788 .. 0.79
   6 !   13.1   0.0   0.00036       0.1       6      35 ..    2038    2067 ..    2033    2151 .. 0.79

  Alignments for each domain:
  == domain 1  score: -0.0 bits;  conditional E-value: 4.1
                 TTSEEEEEESTTSSHHHHHHHHTTSS- CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  10 egekvaivGenGaGKStLlkllagllk 36 
                 e + + +vG   +GK++L++ +a+ + 
  EEA22601.1 289 EQKPLLLVGLPNSGKTSLVNDIAKIMG 315
                 5666789*************9998765 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 0.0016
                 EEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEET.TCEGGG.....B-HHHCCHCEEEE-SS--S-TTS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxx.....xxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran   3 nvslklkegekvaivGenGaGKStLlkllagllkpteGeilld.gkdlke.....qeleslrkeigvlpqepqlfpel 74 
                 ++ + ++ +e v +vGe+G GK+ +++ la+l+ ++   ++l  + ++++     ++ +  +  i  l + +qlf+ +
  EEA22601.1 618 QIAVAVQVSEPVLLVGETGIGKTAVIQQLANLTCQKLTVVNLSqQSESTDllggfRPVNLRSMAIPLLDEFNQLFEST 695
                 788899999*********************998765555555422233336666666666666666666666666665 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 6.6
                  EEESTTSSHHHHHHHHTTSS-- CS
                  xxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran   16 ivGenGaGKStLlkllagllkp 37  
                  + G++ +GK+++++ la+ + +
  EEA22601.1 1066 LQGPTSSGKTSMVEYLAKVSGN 1087
                  78*************9988754 PP

  == domain 4  score: 12.2 bits;  conditional E-value: 0.0007
                  EEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran    5 slklkegekvaivGenGaGKStLlkllagllkpte 39  
                  s  l+++e v +vGe+G+GK+ +++++a+ + +++
  EEA22601.1 1345 SEALRNNEPVLLVGETGCGKTQICQAVAEIYGKEM 1379
                  567888999*****************999887644 PP

  == domain 5  score: 5.9 bits;  conditional E-value: 0.06
                  EETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran    8 lkegekvaivGenGaGKStLlkllagllkpteGei 42  
                  l+ ++ + + G+ G GK+tL++ la+ l +   +i
  EEA22601.1 1732 LQTSKPILLEGSPGVGKTTLVASLARALGKPLTRI 1766
                  5667778899**************99876655555 PP

  == domain 6  score: 13.1 bits;  conditional E-value: 0.00036
                  EEEETTSEEEEEESTTSSHHHHHHHHTTSS CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran    6 lklkegekvaivGenGaGKStLlkllagll 35  
                  + +++     +vG++G+GK+t +++la   
  EEA22601.1 2038 FCIERAWPSILVGPSGCGKTTTIRTLASIQ 2067
                  66666667789***************9875 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0       1.4     4e+02       2      23 ..     294     315 ..     293     333 .. 0.82
   2 ?    7.1   0.0     0.024       6.9       1      26 [.     629     654 ..     629     700 .. 0.88
   3 ?    3.8   0.0      0.25        72       1      26 [.    1064    1089 ..    1064    1110 .. 0.80
   4 ?    6.5   0.0     0.037        10       1      26 [.    1354    1379 ..    1354    1394 .. 0.80
   5 !   10.1   0.0    0.0029      0.84       1      26 [.    1738    1763 ..    1738    1776 .. 0.85
   6 ?    6.9   0.0     0.029       8.1       2      20 ..    2047    2065 ..    2046    2082 .. 0.88

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 1.4
  RNA_helicase   2 wlyGpsgeGKStlakeLakall 23 
                   +l+G ++ GK++l++++ak + 
    EEA22601.1 294 LLVGLPNSGKTSLVNDIAKIMG 315
                   6899************887665 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.024
  RNA_helicase   1 iwlyGpsgeGKStlakeLakallkkl 26 
                   ++l+G++g+GK+ ++++La+  ++kl
    EEA22601.1 629 VLLVGETGIGKTAVIQQLANLTCQKL 654
                   5799***************9999887 PP

  == domain 3  score: 3.8 bits;  conditional E-value: 0.25
  RNA_helicase    1 iwlyGpsgeGKStlakeLakallkkl 26  
                    i+l+Gp+  GK++++++Lak   +k+
    EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAKVSGNKF 1089
                    6899*************998777666 PP

  == domain 4  score: 6.5 bits;  conditional E-value: 0.037
  RNA_helicase    1 iwlyGpsgeGKStlakeLakallkkl 26  
                    ++l+G++g+GK+++++ +a+   k++
    EEA22601.1 1354 VLLVGETGCGKTQICQAVAEIYGKEM 1379
                    5799************9776655554 PP

  == domain 5  score: 10.1 bits;  conditional E-value: 0.0029
  RNA_helicase    1 iwlyGpsgeGKStlakeLakallkkl 26  
                    i+l G++g+GK+tl+ +La+al k l
    EEA22601.1 1738 ILLEGSPGVGKTTLVASLARALGKPL 1763
                    6799******************9776 PP

  == domain 6  score: 6.9 bits;  conditional E-value: 0.029
  RNA_helicase    2 wlyGpsgeGKStlakeLak 20  
                    +l+Gpsg+GK+t++++La+
    EEA22601.1 2047 ILVGPSGCGKTTTIRTLAS 2065
                    589************9986 PP

>> Sigma54_activ_2  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.6   0.1   2.7e-06   0.00078       8      64 ..     613     668 ..     606     713 .. 0.81
   2 ?    5.1   0.0      0.08        23       9      56 ..    1049    1094 ..    1044    1123 .. 0.77
   3 !   10.6   0.0    0.0016      0.45       6      53 ..    1336    1383 ..    1333    1394 .. 0.83
   4 ?   -0.3   0.0       3.7   1.1e+03      18      43 ..    1732    1757 ..    1719    1780 .. 0.69
   5 ?   -1.3   0.0       7.8   2.2e+03      23      47 ..    2045    2069 ..    2038    2086 .. 0.80

  Alignments for each domain:
  == domain 1  score: 19.6 bits;  conditional E-value: 2.7e-06
                      HHHHHHHHHHHT-SS-EEEEEETT--HHHHHHCC--TTS-EE--SSTTHHHH-HHHH CS
  Sigma54_activ_2   8 qelkerLeqaaqsklpvfltGekGsgkelvArlLhknsgpwleifvverlaklpldl 64 
                       +  e++++a+q + pv+l+Ge G gk+ v + L++  +++l ++++ ++++   dl
       EEA22601.1 613 LKTMEQIAVAVQVSEPVLLVGETGIGKTAVIQQLANLTCQKLTVVNLSQQSE-STDL 668
                      556789**********************************999999965554.4444 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.08
                       HHHHHHHHHHT-SS-EEEEEETT--HHHHHHCC--TTS-EE--SSTTH CS
  Sigma54_activ_2    9 elkerLeqaaqsklpvfltGekGsgkelvArlLhknsgpwleifvver 56  
                       +lk+ L + + + +p++l G+  sgk+++ ++L+k sg+  + +++++
       EEA22601.1 1049 NLKNLLRASSTRRFPILLQGPTSSGKTSMVEYLAKVSGN--KFVRINN 1094
                       678888888999***********************9988..3444433 PP

  == domain 3  score: 10.6 bits;  conditional E-value: 0.0016
                       HHHHHHHHHHHHHT-SS-EEEEEETT--HHHHHHCC--TTS-EE--SS CS
  Sigma54_activ_2    6 aiqelkerLeqaaqsklpvfltGekGsgkelvArlLhknsgpwleifv 53  
                       a+ + +  + +a +++ pv+l+Ge G+gk+ + ++ ++  g+ + i++
       EEA22601.1 1336 AMRRVFVLVSEALRNNEPVLLVGETGCGKTQICQAVAEIYGKEMYIVN 1383
                       56666777788999********************99999888777665 PP

  == domain 4  score: -0.3 bits;  conditional E-value: 3.7
                       HT-SS-EEEEEETT--HHHHHHCC-- CS
  Sigma54_activ_2   18 aqsklpvfltGekGsgkelvArlLhk 43  
                        q + p++l G +G gk++    L+ 
       EEA22601.1 1732 LQTSKPILLEGSPGVGKTTLVASLAR 1757
                       38889***********9875444443 PP

  == domain 5  score: -1.3 bits;  conditional E-value: 7.8
                       -EEEEEETT--HHHHHHCC--TTS- CS
  Sigma54_activ_2   23 pvfltGekGsgkelvArlLhknsgp 47  
                       p  l+G+ G+gk++  r+L++ +g 
       EEA22601.1 2045 PSILVGPSGCGKTTTIRTLASIQGA 2069
                       56799*************9998776 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.0     0.066        19      22      67 ..     290     338 ..     272     413 .. 0.86
   2 ?    5.1   0.0     0.044        13      13      48 ..     617     652 ..     609     668 .. 0.82
   3 ?   -0.4   0.0       2.2   6.3e+02      15      45 ..    1054    1084 ..    1047    1102 .. 0.79
   4 ?    2.6   0.0      0.27        77     110     159 ..    1132    1182 ..    1106    1192 .. 0.83
   5 ?    3.5   0.0      0.14        39      24      46 ..    1353    1375 ..    1334    1408 .. 0.84
   6 ?    5.4   0.0     0.036        10      24      47 ..    1737    1760 ..    1723    1785 .. 0.79
   7 ?    5.0   0.0     0.049        14     110     162 ..    1809    1862 ..    1802    1880 .. 0.89
   8 ?    3.2   0.0      0.18        50      26      46 ..    2047    2067 ..    2043    2083 .. 0.87

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.066
  Mg_chelatase  22 gHnlllvGppGsGKtmlakrlpsll...pplseeealevakiasvagkk 67 
                   +  lllvG p sGKt l + +++++   p++ +    e +  +s+ g+ 
    EEA22601.1 290 QKPLLLVGLPNSGKTSLVNDIAKIMgqgPSMVTLHLNEQTDAKSLLGMY 338
                   5679*******************99555556666666777777776654 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.044
  Mg_chelatase  13 raleiaaaGgHnlllvGppGsGKtmlakrlpsllpp 48 
                   + + +a+  +  +llvG  G GKt ++++l++l ++
    EEA22601.1 617 EQIAVAVQVSEPVLLVGETGIGKTAVIQQLANLTCQ 652
                   456677778889******************998765 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 2.2
  Mg_chelatase   15 leiaaaGgHnlllvGppGsGKtmlakrlpsl 45  
                    l+ + + +  +ll Gp  sGKt + + l+++
    EEA22601.1 1054 LRASSTRRFPILLQGPTSSGKTSMVEYLAKV 1084
                    55555666779***********999888765 PP

  == domain 4  score: 2.6 bits;  conditional E-value: 0.27
  Mg_chelatase  110 LfLDElpefkrkvlevLRePledg.evtisrakakvefparfqlvaamNpc 159 
                    ++LDEl    ++vle+L + l+d+ e+ +  +++ ++   +f+l a+ Np+
    EEA22601.1 1132 IVLDELNLAPSDVLEALNRLLDDNrELFLPETQEVIQPHPNFMLFATQNPA 1182
                    78*******************8752678888888888889*********96 PP

  == domain 5  score: 3.5 bits;  conditional E-value: 0.14
  Mg_chelatase   24 nlllvGppGsGKtmlakrlpsll 46  
                     +llvG  G+GKt + ++++++ 
    EEA22601.1 1353 PVLLVGETGCGKTQICQAVAEIY 1375
                    589**************999886 PP

  == domain 6  score: 5.4 bits;  conditional E-value: 0.036
  Mg_chelatase   24 nlllvGppGsGKtmlakrlpsllp 47  
                     +ll G+pG GKt l + l+  l 
    EEA22601.1 1737 PILLEGSPGVGKTTLVASLARALG 1760
                    589**********99988877664 PP

  == domain 7  score: 5.0 bits;  conditional E-value: 0.049
  Mg_chelatase  110 LfLDElpefkrkvlevLRePled.gevtisrakakvefparfqlvaamNpcpcg 162 
                    ++LDE+   +++vle L + l++ ++v ++  +++++   +f l aa Np   g
    EEA22601.1 1809 VLLDEMNLASQSVLEGLNSCLDHrQQVYVAELDQTFKRHPDFVLFAAQNPHHQG 1862
                    579******************972579*********9999**********8765 PP

  == domain 8  score: 3.2 bits;  conditional E-value: 0.18
  Mg_chelatase   26 llvGppGsGKtmlakrlpsll 46  
                    +lvGp+G+GKt  ++ l+s+ 
    EEA22601.1 2047 ILVGPSGCGKTTTIRTLASIQ 2067
                    79*************999885 PP

>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.1       3.2   9.1e+02      40      71 ..     288     316 ..     270     336 .. 0.77
   2 ?    2.6   0.0      0.39   1.1e+02      48      74 ..     629     655 ..     609     706 .. 0.75
   3 ?    6.4   0.0     0.028       7.9      44      78 ..    1059    1094 ..    1040    1111 .. 0.76
   4 ?    5.0   0.0     0.072        20      46      76 ..    1352    1382 ..    1334    1432 .. 0.82
   5 ?    3.8   0.0      0.17        48      47      73 ..    1737    1763 ..    1727    1774 .. 0.84
   6 !   16.5   0.0   2.1e-05    0.0059      49      75 ..    2047    2073 ..    2040    2093 .. 0.90

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 3.2
       Rad17  40 LesrkkriLLisGPsGCgkstvvkvLskelgi 71 
                 Le+   + LL+ G +  gk+  v+ ++k++g 
  EEA22601.1 288 LEQ---KPLLLVGLPNSGKTSLVNDIAKIMGQ 316
                 333...4689999999************9985 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.39
       Rad17  48 LLisGPsGCgkstvvkvLskelgiklr 74 
                 +L+ G +G gk+ v++ L+     kl 
  EEA22601.1 629 VLLVGETGIGKTAVIQQLANLTCQKLT 655
                 6889**************987666553 PP

  == domain 3  score: 6.4 bits;  conditional E-value: 0.028
       Rad17   44 kkr.iLLisGPsGCgkstvvkvLskelgiklrewln 78  
                   +r  +L+ GP+  gk+ +v+ L+k  g k+    n
  EEA22601.1 1059 TRRfPILLQGPTSSGKTSMVEYLAKVSGNKFVRINN 1094
                  33335789********************99876655 PP

  == domain 4  score: 5.0 bits;  conditional E-value: 0.072
       Rad17   46 riLLisGPsGCgkstvvkvLskelgiklrew 76  
                  + +L+ G +GCgk+ + + ++ ++g ++   
  EEA22601.1 1352 EPVLLVGETGCGKTQICQAVAEIYGKEMYIV 1382
                  446788*****************99887554 PP

  == domain 5  score: 3.8 bits;  conditional E-value: 0.17
       Rad17   47 iLLisGPsGCgkstvvkvLskelgikl 73  
                   +L+ G +G gk+t v  L++ lg  l
  EEA22601.1 1737 PILLEGSPGVGKTTLVASLARALGKPL 1763
                  46889****************999765 PP

  == domain 6  score: 16.5 bits;  conditional E-value: 2.1e-05
       Rad17   49 LisGPsGCgkstvvkvLskelgiklre 75  
                  ++ GPsGCgk+t+++ L+ + g +l e
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLASIQGAELVE 2073
                  578******************999877 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.0     0.029       8.1      19      51 ..     293     325 ..     279     376 .. 0.79
   2 ?    2.8   0.1      0.22        62      19      49 ..     629     659 ..     614     663 .. 0.81
   3 ?    4.3   0.0     0.075        21      17     100 ..    1062    1134 ..    1049    1157 .. 0.69
   4 ?    5.0   0.0     0.044        13      19      40 ..    1354    1375 ..    1345    1385 .. 0.83
   5 ?    5.7   0.0     0.028       8.1      17      49 ..    1736    1766 ..    1722    1772 .. 0.80
   6 ?    1.8   0.0      0.42   1.2e+02      20      38 ..    2047    2065 ..    2041    2083 .. 0.83
   7 ?    1.8   0.0      0.43   1.2e+02      71     124 ..    2174    2228 ..    2155    2229 .. 0.83
   8 ?    0.7   0.0      0.96   2.7e+02      48     146 ..    3153    3256 ..    3139    3277 .. 0.60

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.029
  Zeta_toxin  19 illgGqpGAGKselaellkdelerqgnvvrldp 51 
                 +ll+G p +GK++l +++++ ++++ ++v+l  
  EEA22601.1 293 LLLVGLPNSGKTSLVNDIAKIMGQGPSMVTLHL 325
                 6899*******************9999999865 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.22
  Zeta_toxin  19 illgGqpGAGKselaellkdelerqgnvvrl 49 
                 +ll+G +G GK+++++ l++ + ++  vv l
  EEA22601.1 629 VLLVGETGIGKTAVIQQLANLTCQKLTVVNL 659
                 799*************999877666666665 PP

  == domain 3  score: 4.3 bits;  conditional E-value: 0.075
  Zeta_toxin   17 klillgGqpGAGKselaellkdelerqgnvvrldpDdlRelhPeyeeilkadpkkaseltqkdaselvekllqeaiengyniiv 100 
                    ill G + +GK+++ e+l++    ++++vr++  +   l  ey +         +  t++ + + +e +l ea+ ngy i++
  EEA22601.1 1062 FPILLQGPTSSGKTSMVEYLAKVS--GNKFVRINNHEHTDLQ-EYLG--------SYVSTDDGSLKYQEGVLVEALRNGYWIVL 1134
                  558999*****************8..9******975433333.3333........33345555555566666666666666655 PP

  == domain 4  score: 5.0 bits;  conditional E-value: 0.044
  Zeta_toxin   19 illgGqpGAGKselaellkdel 40  
                  +ll+G +G+GK+++ +++++  
  EEA22601.1 1354 VLLVGETGCGKTQICQAVAEIY 1375
                  79*************9998755 PP

  == domain 5  score: 5.7 bits;  conditional E-value: 0.028
  Zeta_toxin   17 klillgGqpGAGKselaellkdelerqgnvvrl 49  
                  k ill G+pG GK++l + l+++l  ++   r+
  EEA22601.1 1736 KPILLEGSPGVGKTTLVASLARAL--GKPLTRI 1766
                  6699****************9999..5555554 PP

  == domain 6  score: 1.8 bits;  conditional E-value: 0.42
  Zeta_toxin   20 llgGqpGAGKselaellkd 38  
                  +l+G +G+GK+++++ l+ 
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLAS 2065
                  799***********98865 PP

  == domain 7  score: 1.8 bits;  conditional E-value: 0.43
  Zeta_toxin   71 kaseltqkdaselvekllqeaiengyniivegt.lrspdvvkklaealkkaGYev 124 
                  ++s+ ++k   e++e +l+eai+ g  ++++ + l + +v+++l   ++ +GY v
  EEA22601.1 2174 QTSKDAHKVGFEWTEGALTEAIQLGHWVVLDNAnLCNASVLDRLNSLMEPNGYLV 2228
                  566777888889*******************876888888888888888888865 PP

  == domain 8  score: 0.7 bits;  conditional E-value: 0.96
  Zeta_toxin   48 rldpDdlRelhPeyeeilkadpkk.aseltqk..daselvekllq..eaiengyniivegt..lrspdvvkklaealkkaGYevevvvvavkkelSr 137 
                  ++d+ +lRel+P ye+ ++++++k   + t+     +el + ++    +  n + +ive+t  l s +  +    +++ + Y   +++v  ++  S+
  EEA22601.1 3153 EVDEAELRELFPVYEGNEQEESEKsRMDITSIslKLTELHAAIFSpgDIEANLRQFIVESTrlLGSLSSGE--ESSAAPKSYLPGILLVLKDELKSY 3247
                  588999*********97775433303333332113444555555422334455667777774444444444..444444447777777777777777 PP

  Zeta_toxin  138 lgvldRyee 146 
                  + v  R+ +
  EEA22601.1 3248 ENVSPRHYN 3256
                  777777655 PP

>> SRP54  SRP54-type protein, GTPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0       2.3   6.7e+02       4      27 ..     293     316 ..     290     324 .. 0.84
   2 ?    7.4   0.1     0.011       3.1       4      28 ..     629     653 ..     626     661 .. 0.85
   3 ?   -1.9   0.0       7.4   2.1e+03       4      25 ..    1064    1085 ..    1062    1091 .. 0.87
   4 ?    6.6   0.0     0.019       5.5       4      29 ..    1354    1383 ..    1351    1397 .. 0.80
   5 !    7.7   0.0    0.0087       2.5       4      27 ..    1738    1761 ..    1735    1769 .. 0.86
   6 !   11.4   0.0   0.00063      0.18       5      49 ..    2047    2093 ..    2045    2121 .. 0.82

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 2.3
                 EEEEESTTSSHHHHHHHHHHHHHH CS
       SRP54   4 illvGlqGaGKTttlaKLaallkk 27 
                 +llvGl  +GKT+ +  +a+++ +
  EEA22601.1 293 LLLVGLPNSGKTSLVNDIAKIMGQ 316
                 79***************9998755 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.011
                 EEEEESTTSSHHHHHHHHHHHHHHT CS
       SRP54   4 illvGlqGaGKTttlaKLaallkke 28 
                 +llvG +G+GKT  + +La+l  ++
  EEA22601.1 629 VLLVGETGIGKTAVIQQLANLTCQK 653
                 79*****************998766 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 7.4
                  EEEEESTTSSHHHHHHHHHHHH CS
       SRP54    4 illvGlqGaGKTttlaKLaall 25  
                  ill G++ +GKT+ +  La++ 
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAKVS 1085
                  8999************999876 PP

  == domain 4  score: 6.6 bits;  conditional E-value: 0.019
                  EEEEESTTSSHHHHHHHHHHHHHHT....T CS
       SRP54    4 illvGlqGaGKTttlaKLaallkke....g 29  
                  +llvG +G GKT+ +  +a+++ ke    +
  EEA22601.1 1354 VLLVGETGCGKTQICQAVAEIYGKEmyivN 1383
                  79*******************999844444 PP

  == domain 5  score: 7.7 bits;  conditional E-value: 0.0087
                  EEEEESTTSSHHHHHHHHHHHHHH CS
       SRP54    4 illvGlqGaGKTttlaKLaallkk 27  
                  ill G  G+GKTt +a La+ l k
  EEA22601.1 1738 ILLEGSPGVGKTTLVASLARALGK 1761
                  8999***************98865 PP

  == domain 6  score: 11.4 bits;  conditional E-value: 0.00063
                  EEEESTTSSHHHHHHHHHHHHHHTTS-EEEEE.ESTSS.TTHHHHHH CS
       SRP54    5 llvGlqGaGKTttlaKLaallkkegkkvllva.aDtfR.aaAveQLk 49  
                  +lvG+ G GKTtt+  La +  +e  +++l a +Dt+  ++ +eQ+ 
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLASIQGAELVELALSAdTDTMDlIGGFEQID 2093
                  79*****************9999988888876467764367777775 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.0      0.25        71       6      36 ..     285     316 ..     281     325 .. 0.85
   2 ?    6.9   0.1     0.026       7.3       4      37 ..     620     653 ..     617     662 .. 0.81
   3 ?   -1.3   0.0       8.5   2.4e+03      37      67 ..    1056    1086 ..    1043    1160 .. 0.42
   4 ?    6.0   0.0     0.049        14       8      37 ..    1349    1378 ..    1344    1515 .. 0.88
   5 ?    8.1   0.1     0.011       3.2       8      34 ..    1733    1759 ..    1726    1767 .. 0.82
   6 ?    5.9   0.0     0.052        15      12      32 ..    2045    2065 ..    2037    2077 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.25
      AAA_19   6 e.alkekvllvtaGpGtGKTrvlkhivallve 36 
                 +  l++k+ll+++ p +GKT +++ i +++ +
  EEA22601.1 285 NaLLEQKPLLLVGLPNSGKTSLVNDIAKIMGQ 316
                 446899******************99998865 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.026
      AAA_19   4 avealkekvllvtaGpGtGKTrvlkhivallvel 37 
                 av+   ++++l+++  G GKT v+++  +l  + 
  EEA22601.1 620 AVAVQVSEPVLLVGETGIGKTAVIQQLANLTCQK 653
                 6666778999***************998876655 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 8.5
      AAA_19   37 lggvkpeeillvaftgrAakelrerlaalga 67  
                  + +    +ill  +t+     + e la++ +
  EEA22601.1 1056 ASSTRRFPILLQGPTSSGKTSMVEYLAKVSG 1086
                  4444445555555555555555555533222 PP

  == domain 4  score: 6.0 bits;  conditional E-value: 0.049
      AAA_19    8 lkekvllvtaGpGtGKTrvlkhivallvel 37  
                   +++++l+++  G+GKT++ +++ +++ ++
  EEA22601.1 1349 RNNEPVLLVGETGCGKTQICQAVAEIYGKE 1378
                  57899****************999988765 PP

  == domain 5  score: 8.1 bits;  conditional E-value: 0.011
      AAA_19    8 lkekvllvtaGpGtGKTrvlkhivall 34  
                   ++k++l+ + pG GKT+++    + l
  EEA22601.1 1733 QTSKPILLEGSPGVGKTTLVASLARAL 1759
                  5789**************998877665 PP

  == domain 6  score: 5.9 bits;  conditional E-value: 0.052
      AAA_19   12 vllvtaGpGtGKTrvlkhiva 32  
                  + +++++ G+GKT+++++  +
  EEA22601.1 2045 PSILVGPSGCGKTTTIRTLAS 2065
                  67999***********98765 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.0       2.5     7e+02       3      27 ..     293     317 ..     291     323 .. 0.86
   2 !    8.4   0.1    0.0068       1.9       2      23 ..     628     649 ..     627     655 .. 0.89
   3 ?    5.3   0.0     0.058        17       2      22 ..    1353    1373 ..    1352    1417 .. 0.91
   4 !   13.8   0.0   0.00014     0.041       2      26 ..    1737    1761 ..    1736    1765 .. 0.91
   5 ?    5.7   0.0     0.043        12       3      22 ..    2046    2065 ..    2045    2070 .. 0.90

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 2.5
                 EEEEC-TTTCHHHHHHHHHHHHCTS CS
       NACHT   3 vilqGeaGsGKTtLlqklalawaeg 27 
                 ++l G + sGKT L+  +a  + +g
  EEA22601.1 293 LLLVGLPNSGKTSLVNDIAKIMGQG 317
                 78999999**********9887765 PP

  == domain 2  score: 8.4 bits;  conditional E-value: 0.0068
                 CEEEEC-TTTCHHHHHHHHHHH CS
       NACHT   2 lvilqGeaGsGKTtLlqklala 23 
                 +v+l Ge G+GKT+ +q+la +
  EEA22601.1 628 PVLLVGETGIGKTAVIQQLANL 649
                 699***************9975 PP

  == domain 3  score: 5.3 bits;  conditional E-value: 0.058
                  CEEEEC-TTTCHHHHHHHHHH CS
       NACHT    2 lvilqGeaGsGKTtLlqklal 22  
                  +v+l Ge G+GKT   q +a+
  EEA22601.1 1353 PVLLVGETGCGKTQICQAVAE 1373
                  699**********99999886 PP

  == domain 4  score: 13.8 bits;  conditional E-value: 0.00014
                  CEEEEC-TTTCHHHHHHHHHHHHCT CS
       NACHT    2 lvilqGeaGsGKTtLlqklalawae 26  
                  +++l+G +G+GKTtL+++la+a+ +
  EEA22601.1 1737 PILLEGSPGVGKTTLVASLARALGK 1761
                  689*****************99876 PP

  == domain 5  score: 5.7 bits;  conditional E-value: 0.043
                  EEEEC-TTTCHHHHHHHHHH CS
       NACHT    3 vilqGeaGsGKTtLlqklal 22  
                  +il G++G+GKTt ++ la+
  EEA22601.1 2046 SILVGPSGCGKTTTIRTLAS 2065
                  699***********999986 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0      0.47   1.3e+02      88     121 ..     278     312 ..     260     329 .. 0.76
   2 !   11.5   0.2   0.00072      0.21      60     133 ..     587     662 ..     583     666 .. 0.77
   3 ?    2.4   0.0      0.46   1.3e+02      87     120 ..    1338    1372 ..    1294    1393 .. 0.72
   4 ?    6.7   0.0     0.022       6.3      92     122 ..    1727    1758 ..    1711    1772 .. 0.77
   5 ?    7.7   0.0     0.011         3     102     123 ..    2046    2067 ..    2012    2081 .. 0.82

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.47
                  TTHHHHHHH.CTTSEEEEECSTTSSHHHHHHHHCT CS
  RsgA_GTPase  88 egleelkel.lkdktsvlvGqSGvGKStLinallp 121
                  ++l++++++ l++k  +lvG    GK++L+n ++ 
   EEA22601.1 278 NNLRSVANAlLEQKPLLLVGLPNSGKTSLVNDIAK 312
                  455566555156699****************9976 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 0.00072
                  -HHHHHHHHHHHHHHTTSEEEE--TTTHTTHHHHHHHCTT.SEEEEECSTTSSHHHHHHHHCT..T-----S----- CS
  RsgA_GTPase  60 eeeeeleelkeelealgyevllvsaktkegleelkellkd.ktsvlvGqSGvGKStLinallp..elelktgevsek 133
                   +++ ++++k+++++l  ++  ++a   +++e+++ +++  + ++lvG++G+GK+++i +l++   ++l + ++s++
   EEA22601.1 587 MKMKVTKTTKARFNKLSARFAPTRAA-LKTMEQIAVAVQVsEPVLLVGETGIGKTAVIQQLANltCQKLTVVNLSQQ 662
                  55566677888888888888887666.788999999999879999****************9854556666666665 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.46
                   HTTHHHHHHHCTT.SEEEEECSTTSSHHHHHHHHC CS
  RsgA_GTPase   87 kegleelkellkd.ktsvlvGqSGvGKStLinall 120 
                   ++ +  ++e+l++ + ++lvG++G GK+ +  a++
   EEA22601.1 1338 RRVFVLVSEALRNnEPVLLVGETGCGKTQICQAVA 1372
                   455556777888868899**********9987765 PP

  == domain 4  score: 6.7 bits;  conditional E-value: 0.022
                   HHHHHCTT.SEEEEECSTTSSHHHHHHHHCTT CS
  RsgA_GTPase   92 elkellkd.ktsvlvGqSGvGKStLinallpe 122 
                   ++++ l+  k ++l G+ GvGK+tL+ +l+  
   EEA22601.1 1727 RIARGLQTsKPILLEGSPGVGKTTLVASLARA 1758
                   566667766888999***********999875 PP

  == domain 5  score: 7.7 bits;  conditional E-value: 0.011
                   EEEECSTTSSHHHHHHHHCTT- CS
  RsgA_GTPase  102 svlvGqSGvGKStLinallpel 123 
                   s+lvG+SG GK+t i +l++ +
   EEA22601.1 2046 SILVGPSGCGKTTTIRTLASIQ 2067
                   89***************99854 PP

>> T2SSE  Type II/IV secretion system protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.0      0.59   1.7e+02     107     155 ..     269     316 ..     262     324 .. 0.79
   2 ?    3.6   0.0       0.1        30     101     149 ..     587     646 ..     553     659 .. 0.65
   3 !   16.2   0.0   1.5e-05    0.0041     107     150 ..    1039    1082 ..    1028    1123 .. 0.85
   4 ?    3.6   0.0       0.1        29     119     155 ..    1341    1377 ..    1308    1391 .. 0.77
   5 ?    2.0   0.1      0.32        90     124     159 ..    1730    1765 ..    1713    1772 .. 0.79
   6 ?    1.8   0.0      0.35        99     132     155 ..    2046    2069 ..    2007    2112 .. 0.74

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.59
       T2SSE 107 dlgaeealkekiaevlrkavrerglilvsGgTgsGKttllyallkeink 155
                  l+++e++++++++v ++   e++ +l+ G   sGKt l++ + k++ +
  EEA22601.1 269 SLVKTETVTNNLRSVANAL-LEQKPLLLVGLPNSGKTSLVNDIAKIMGQ 316
                 5778888888888776666.788888888999********998877655 PP

  == domain 2  score: 3.6 bits;  conditional E-value: 0.1
       T2SSE 101 keltlddlgaeealk...........ekiaevlrkavrerglilvsGgTgsGKttllyal 149
                 +++++ +  +++ +k            k  e ++ av+    +l+ G Tg GKt ++  l
  EEA22601.1 587 MKMKVTKTTKARFNKlsarfaptraaLKTMEQIAVAVQVSEPVLLVGETGIGKTAVIQQL 646
                 4444444333333334444444444444455677899999**************988665 PP

  == domain 3  score: 16.2 bits;  conditional E-value: 1.5e-05
       T2SSE  107 dlgaeealkekiaevlrkavrerglilvsGgTgsGKttllyall 150 
                  ++++++  +++++++lr++ ++r  il+ G+T+sGKt ++  l 
  EEA22601.1 1039 HYIITPFIEKNLKNLLRASSTRRFPILLQGPTSSGKTSMVEYLA 1082
                  577888899****************************9886554 PP

  == domain 4  score: 3.6 bits;  conditional E-value: 0.1
       T2SSE  119 aevlrkavrerglilvsGgTgsGKttllyallkeink 155 
                    ++++a+r++  +l+ G Tg GKt +  a+ ++  k
  EEA22601.1 1341 FVLVSEALRNNEPVLLVGETGCGKTQICQAVAEIYGK 1377
                  456788899999*************999887766555 PP

  == domain 5  score: 2.0 bits;  conditional E-value: 0.32
       T2SSE  124 kavrerglilvsGgTgsGKttllyallkeinksder 159 
                  + +++ + il+ G  g GKttl+ +l   + k   r
  EEA22601.1 1730 RGLQTSKPILLEGSPGVGKTTLVASLARALGKPLTR 1765
                  44566799**************99998888776555 PP

  == domain 6  score: 1.8 bits;  conditional E-value: 0.35
       T2SSE  132 ilvsGgTgsGKttllyallkeink 155 
                   ++ G+ g GKtt++ +l ++  +
  EEA22601.1 2046 SILVGPSGCGKTTTIRTLASIQGA 2069
                  4677**********9988766555 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.44   1.3e+02      30      56 ..     287     313 ..     272     327 .. 0.81
   2 ?    3.4   0.0      0.17        48      34      58 ..     627     651 ..     596     662 .. 0.85
   3 ?    4.4   0.0     0.087        25      24      52 ..    1342    1370 ..    1326    1375 .. 0.84
   4 !   10.2   0.0    0.0014       0.4      31      57 ..    1733    1759 ..    1715    1772 .. 0.82
   5 ?    6.3   0.0     0.023       6.5      29      51 ..    2039    2061 ..    2010    2066 .. 0.72

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.44
      AAA_25  30 lpagelallaGapgtGKttlaldlala 56 
                 l +++  ll+G p +GKt l+ d+a  
  EEA22601.1 287 LLEQKPLLLVGLPNSGKTSLVNDIAKI 313
                 4578999*************9998865 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.17
      AAA_25  34 elallaGapgtGKttlaldlalava 58 
                 e +ll+G +g GKt++  +la  ++
  EEA22601.1 627 EPVLLVGETGIGKTAVIQQLANLTC 651
                 679****************996555 PP

  == domain 3  score: 4.4 bits;  conditional E-value: 0.087
      AAA_25   24 wlvkgllpagelallaGapgtGKttlald 52  
                   lv + l+ +e +ll+G +g+GKt ++  
  EEA22601.1 1342 VLVSEALRNNEPVLLVGETGCGKTQICQA 1370
                  588889999***************88765 PP

  == domain 4  score: 10.2 bits;  conditional E-value: 0.0014
      AAA_25   31 pagelallaGapgtGKttlaldlalav 57  
                     + +ll G pg+GKttl+ +la a+
  EEA22601.1 1733 QTSKPILLEGSPGVGKTTLVASLARAL 1759
                  567889***************999763 PP

  == domain 5  score: 6.3 bits;  conditional E-value: 0.023
      AAA_25   29 llpagelallaGapgtGKttlal 51  
                  ++ + + ++l+G++g+GKtt   
  EEA22601.1 2039 CIERAWPSILVGPSGCGKTTTIR 2061
                  4588999************9765 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.0      0.47   1.3e+02      20      42 ..     290     312 ..     278     326 .. 0.84
   2 ?    5.5   0.0     0.051        15       7      44 ..     612     650 ..     609     701 .. 0.85
   3 ?    5.8   0.0     0.039        11       5      44 ..    1047    1085 ..    1047    1130 .. 0.82
   4 ?    5.5   0.0     0.049        14      19     106 ..    1350    1443 ..    1342    1454 .. 0.74
   5 ?   -0.4   0.0       3.1   8.9e+02      18      42 ..    1733    1757 ..    1726    1763 .. 0.84
   6 ?    4.3   0.0      0.12        33      20      42 ..    2043    2065 ..    2033    2118 .. 0.89

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.47
    ATPase_2  20 neiyfiYGpegsGKtaLlkeiie 42 
                 ++++++ G  +sGKt+L++ i++
  EEA22601.1 290 QKPLLLVGLPNSGKTSLVNDIAK 312
                 6789999************9986 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.051
    ATPase_2   7 elkeleeil.erepneiyfiYGpegsGKtaLlkeiienl 44 
                 +lk +e+i+   + +e++++ G  g+GKta+++++++  
  EEA22601.1 612 ALKTMEQIAvAVQVSEPVLLVGETGIGKTAVIQQLANLT 650
                 56677776524567899*****************99976 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.039
    ATPase_2    5 ekelkeleeilerepneiyfiYGpegsGKtaLlkeiienl 44  
                  ek lk+l++   ++++ ++++ Gp +sGKt+++  +++ +
  EEA22601.1 1047 EKNLKNLLRAS-STRRFPILLQGPTSSGKTSMVEYLAKVS 1085
                  67788887755.55999***************99988876 PP

  == domain 4  score: 5.5 bits;  conditional E-value: 0.049
    ATPase_2   19 pneiyfiYGpegsGKtaLlkeiienledkdkyviyyialreesiskldefie.....eeeekkklekalgiavpkaeleeilk..eksklvfkai 106 
                  +ne++++ G  g+GKt++ + ++e   +  + v    +l++ +i  +++ ++     e +  + l+ ++ +++p ae+++ +k  ++ k +f+++
  EEA22601.1 1350 NNEPVLLVGETGCGKTQICQAVAEIYGKEMYIVNAHVNLETGDIVGAQRPLRnrsaiERQLCDDLASVI-STLPDAEIDQSSKslDNLKAAFAQL 1443
                  689999****************99998888888888899998888888887665444444444444444.6777777777666666666666555 PP

  == domain 5  score: -0.4 bits;  conditional E-value: 3.1
    ATPase_2   18 epneiyfiYGpegsGKtaLlkeiie 42  
                  ++++++++ G+ g+GKt+L+  ++ 
  EEA22601.1 1733 QTSKPILLEGSPGVGKTTLVASLAR 1757
                  578899999**********987765 PP

  == domain 6  score: 4.3 bits;  conditional E-value: 0.12
    ATPase_2   20 neiyfiYGpegsGKtaLlkeiie 42  
                  + +  + Gp g+GKt+ ++ +++
  EEA22601.1 2043 AWPSILVGPSGCGKTTTIRTLAS 2065
                  6677888***********98875 PP

>> TniB  Bacterial TniB protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0      0.21        61      19      56 ..     276     311 ..     270     321 .. 0.77
   2 !    7.5   0.0    0.0086       2.5      16      58 ..     609     649 ..     600     669 .. 0.82
   3 ?    6.3   0.0      0.02       5.7      19      58 ..    1046    1084 ..    1036    1099 .. 0.84
   4 ?    5.1   0.0     0.048        14      36      57 ..    1352    1373 ..    1334    1399 .. 0.81
   5 ?   -2.5   0.0       9.8   2.8e+03      37      57 ..    1737    1757 ..    1730    1761 .. 0.84
   6 ?    0.7   0.0       1.1     3e+02      38      56 ..    2046    2064 ..    2033    2074 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.21
        TniB  19 ilerLeeLleypkrkrmpnlllvGdsnnGKtmivekFa 56 
                 ++++L+++ ++  +++   lllvG +n GKt++v+  a
  EEA22601.1 276 VTNNLRSVANALLEQK--PLLLVGLPNSGKTSLVNDIA 311
                 5566666666666655..79*************99766 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0086
        TniB  16 akeilerLeeLleypkrkrmpnlllvGdsnnGKtmivekFarl 58 
                  +++l+++e++  + + ++   +llvG++ +GKt+++++ a+l
  EEA22601.1 609 TRAALKTMEQIAVAVQVSE--PVLLVGETGIGKTAVIQQLANL 649
                 5678888888888877777..799**************98876 PP

  == domain 3  score: 6.3 bits;  conditional E-value: 0.02
        TniB   19 ilerLeeLleypkrkrmpnlllvGdsnnGKtmivekFarl 58  
                  i ++L++Ll++ +  r p +ll G++  GKt++ve  a+ 
  EEA22601.1 1046 IEKNLKNLLRASSTRRFP-ILLQGPTSSGKTSMVEYLAKV 1084
                  67899*****99999976.789************988765 PP

  == domain 4  score: 5.1 bits;  conditional E-value: 0.048
        TniB   36 pnlllvGdsnnGKtmivekFar 57  
                  + +llvG++ +GKt+i++  a+
  EEA22601.1 1352 EPVLLVGETGCGKTQICQAVAE 1373
                  4689*************98765 PP

  == domain 5  score: -2.5 bits;  conditional E-value: 9.8
        TniB   37 nlllvGdsnnGKtmivekFar 57  
                   +ll G + +GKt++v + ar
  EEA22601.1 1737 PILLEGSPGVGKTTLVASLAR 1757
                  57999**********987665 PP

  == domain 6  score: 0.7 bits;  conditional E-value: 1.1
        TniB   38 lllvGdsnnGKtmivekFa 56  
                   +lvG+s +GKt+ ++  a
  EEA22601.1 2046 SILVGPSGCGKTTTIRTLA 2064
                  5799*********999766 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   0.0      0.65   1.8e+02      36      60 ..     293     317 ..     270     338 .. 0.81
   2 ?    3.2   0.0      0.23        66      34      77 ..     627     670 ..     610     695 .. 0.71
   3 ?    2.5   0.0      0.38   1.1e+02       9      59 ..    1040    1087 ..    1034    1096 .. 0.82
   4 !    8.4   0.0     0.006       1.7      24      83 ..    1345    1401 ..    1325    1409 .. 0.78
   5 !    9.9   0.0     0.002      0.57      34      61 ..    1736    1763 ..    1721    1778 .. 0.84
   6 ?    0.6   0.0       1.5   4.3e+02      37      61 ..    2047    2071 ..    2043    2094 .. 0.80

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.65
      RuvB_N  36 vllyGpPGlGkttlakiiakelgvk 60 
                 +ll+G P  Gkt+l + iak +g  
  EEA22601.1 293 LLLVGLPNSGKTSLVNDIAKIMGQG 317
                 79*****************999865 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.23
      RuvB_N  34 dhvllyGpPGlGkttlakiiakelgvklkitsgPvlekagdlaa 77 
                 + vll+G  G+Gkt++ + +a+    kl +      ++++dl +
  EEA22601.1 627 EPVLLVGETGIGKTAVIQQLANLTCQKLTVVNLSQQSESTDLLG 670
                 569************99999998777777776666666666655 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.38
      RuvB_N    9 yigqekvkeklkifieaakkreealdhvllyGpPGlGkttlakiiakelgv 59  
                  yi    ++++lk +++a+ +r+ +   +ll+Gp   Gkt++ + +ak  g 
  EEA22601.1 1040 YIITPFIEKNLKNLLRASSTRRFP---ILLQGPTSSGKTSMVEYLAKVSGN 1087
                  566666788899999999998876...8**************999986655 PP

  == domain 4  score: 8.4 bits;  conditional E-value: 0.006
      RuvB_N   24 eaakkreealdhvllyGpPGlGkttlakiiakelgvklkitsgPvlekagdlaalltnle 83  
                  + a + +   + vll+G  G Gkt +++ +a+  g ++ i  + v  ++gd+++    l+
  EEA22601.1 1345 SEALRNN---EPVLLVGETGCGKTQICQAVAEIYGKEMYIVNAHVNLETGDIVGAQRPLR 1401
                  4444333...459****************************9999999999998766665 PP

  == domain 5  score: 9.9 bits;  conditional E-value: 0.002
      RuvB_N   34 dhvllyGpPGlGkttlakiiakelgvkl 61  
                    +ll G+PG+Gkttl + +a+ lg  l
  EEA22601.1 1736 KPILLEGSPGVGKTTLVASLARALGKPL 1763
                  569******************9999766 PP

  == domain 6  score: 0.6 bits;  conditional E-value: 1.5
      RuvB_N   37 llyGpPGlGkttlakiiakelgvkl 61  
                  +l+Gp G Gktt  + +a+  g++l
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLASIQGAEL 2071
                  799********98888877666655 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0       2.7   7.7e+02      32      75 ..     272     312 ..     252     334 .. 0.72
   2 !    9.2   0.1    0.0022      0.62      36      90 ..     609     662 ..     580     669 .. 0.73
   3 ?   -0.1   0.0       1.5   4.3e+02      55      93 ..    1063    1101 ..    1045    1107 .. 0.74
   4 ?    6.2   0.0     0.018       5.2      54      84 ..    1352    1381 ..    1334    1416 .. 0.74
   5 ?    6.0   0.0      0.02       5.8      41      84 ..    1722    1766 ..    1717    1779 .. 0.75
   6 ?    0.5   0.0      0.96   2.7e+02      56      78 ..    2046    2068 ..    2040    2097 .. 0.78

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 2.7
      DUF815  32 gidkqkealventeqfleglpannvLLwGarGtGKSslvkalln 75 
                   ++  ++l + ++++le+   + +LL+G   +GK slv  + +
  EEA22601.1 272 KTETVTNNLRSVANALLEQ---KPLLLVGLPNSGKTSLVNDIAK 312
                 4444444444444444444...4589*************98765 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.0022
      DUF815  36 qkealventeqfleglpannvLLwGarGtGKSslvkallneyaeegLrlieveke 90 
                  ++al++  +  ++ + ++ vLL+G+ G GK ++++ l n ++ ++L +++++++
  EEA22601.1 609 TRAALKTMEQIAVAVQVSEPVLLVGETGIGKTAVIQQLAN-LTCQKLTVVNLSQQ 662
                 44555555555567778899***************99876.56678999988775 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 1.5
      DUF815   55 nvLLwGarGtGKSslvkallneyaeegLrlievekedlk 93  
                   +LL G   +GK s+v  l +   ++ +r+ + e++dl+
  EEA22601.1 1063 PILLQGPTSSGKTSMVEYLAKVSGNKFVRINNHEHTDLQ 1101
                  48****************999999988888777766665 PP

  == domain 4  score: 6.2 bits;  conditional E-value: 0.018
      DUF815   54 nnvLLwGarGtGKSslvkallneyaeegLrl 84  
                  + vLL+G+ G+GK  +++a+ + y +e   +
  EEA22601.1 1352 EPVLLVGETGCGKTQICQAVAEIYGKEM-YI 1381
                  459****************988776654.44 PP

  == domain 5  score: 6.0 bits;  conditional E-value: 0.02
      DUF815   41 venteqfleglp.annvLLwGarGtGKSslvkallneyaeegLrl 84  
                  ++n  + ++gl+ ++ +LL G+ G+GK +lv +l +++ +   r+
  EEA22601.1 1722 IANSVRIARGLQtSKPILLEGSPGVGKTTLVASLARALGKPLTRI 1766
                  56778888887615679**************99998887765554 PP

  == domain 6  score: 0.5 bits;  conditional E-value: 0.96
      DUF815   56 vLLwGarGtGKSslvkallneya 78  
                   +L+G  G+GK +++++l +   
  EEA22601.1 2046 SILVGPSGCGKTTTIRTLASIQG 2068
                  589*************9876544 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.0      0.05        14      43      74 ..     622     653 ..     583     664 .. 0.70
   2 ?    1.2   0.0      0.95   2.7e+02      46     123 ..    1060    1143 ..    1039    1155 .. 0.71
   3 ?    6.6   0.0     0.021         6      43      68 ..    1347    1372 ..    1328    1383 .. 0.86
   4 ?    6.0   0.0     0.032         9      44      73 ..    1732    1761 ..    1710    1818 .. 0.81
   5 ?    2.6   0.0      0.35     1e+02      44      66 ..    2040    2062 ..    2004    2114 .. 0.69

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.05
   IstB_IS21  43 fiekkenivllGpsGvGKshlaialgveavra 74 
                  ++ +e ++l+G +G+GK+ +   l+  ++++
  EEA22601.1 622 AVQVSEPVLLVGETGIGKTAVIQQLANLTCQK 653
                 3677899************9999998888875 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.95
   IstB_IS21   46 kkenivllGpsGvGKshlaialgveavraglsvlfvrvedLveelk..rarrdgklara....lkrllkvdllilDdlgllpld 123 
                  ++  i+l Gp+  GK+ +   l++   ++ +++     +dL e l   +  +dg+l+ +    +++l +   ++lD+l l p d
  EEA22601.1 1060 RRFPILLQGPTSSGKTSMVEYLAKVSGNKFVRINNHEHTDLQEYLGsyVSTDDGSLKYQegvlVEALRNGYWIVLDELNLAPSD 1143
                  4456999*********99999999999999999999999998888522456667666541111344444478888988888776 PP

  == domain 3  score: 6.6 bits;  conditional E-value: 0.021
   IstB_IS21   43 fiekkenivllGpsGvGKshlaialg 68  
                   ++++e ++l+G +G GK+ +  a++
  EEA22601.1 1347 ALRNNEPVLLVGETGCGKTQICQAVA 1372
                  57899****************99987 PP

  == domain 4  score: 6.0 bits;  conditional E-value: 0.032
   IstB_IS21   44 iekkenivllGpsGvGKshlaialgveavr 73  
                  +++++ i+l G +GvGK+ l ++l+++  +
  EEA22601.1 1732 LQTSKPILLEGSPGVGKTTLVASLARALGK 1761
                  6778889************99999987655 PP

  == domain 5  score: 2.6 bits;  conditional E-value: 0.35
   IstB_IS21   44 iekkenivllGpsGvGKshlaia 66  
                  ie++   +l+GpsG GK+    +
  EEA22601.1 2040 IERAWPSILVGPSGCGKTTTIRT 2062
                  67777789*********964433 PP

>> PduV-EutP  Ethanolamine utilisation - propanediol utilisation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.0       2.2   6.3e+02       2      21 ..     291     310 ..     290     314 .. 0.86
   2 ?    6.5   0.1     0.022       6.3       4      25 ..     629     650 ..     626     670 .. 0.81
   3 ?   -0.5   0.0       3.2     9e+02       4      22 ..    1064    1082 ..    1063    1091 .. 0.88
   4 !   10.2   0.0    0.0016      0.45       4      23 ..    1354    1373 ..    1351    1390 .. 0.86
   5 ?    1.2   0.0      0.97   2.8e+02       2      22 ..    1736    1756 ..    1735    1763 .. 0.88
   6 ?    4.1   0.0      0.13        36       5      23 ..    2047    2065 ..    2045    2121 .. 0.87

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 2.2
   PduV-EutP   2 kkilliGkvgsGKttLtqal 21 
                 k +ll+G  +sGKt+L + +
  EEA22601.1 291 KPLLLVGLPNSGKTSLVNDI 310
                 5689************9877 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.022
   PduV-EutP   4 illiGkvgsGKttLtqalkgee 25 
                 +ll+G++g GKt++ q+l + +
  EEA22601.1 629 VLLVGETGIGKTAVIQQLANLT 650
                 89****************9854 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 3.2
   PduV-EutP    4 illiGkvgsGKttLtqalk 22  
                  ill G++ sGKt++ + l 
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLA 1082
                  8999*********998775 PP

  == domain 4  score: 10.2 bits;  conditional E-value: 0.0016
   PduV-EutP    4 illiGkvgsGKttLtqalkg 23  
                  +ll+G++g+GKt ++qa+ +
  EEA22601.1 1354 VLLVGETGCGKTQICQAVAE 1373
                  89**************9865 PP

  == domain 5  score: 1.2 bits;  conditional E-value: 0.97
   PduV-EutP    2 kkilliGkvgsGKttLtqalk 22  
                  k ill G+ g+GKttL  +l 
  EEA22601.1 1736 KPILLEGSPGVGKTTLVASLA 1756
                  679999**********98885 PP

  == domain 6  score: 4.1 bits;  conditional E-value: 0.13
   PduV-EutP    5 lliGkvgsGKttLtqalkg 23  
                  +l+G++g+GKtt  ++l  
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLAS 2065
                  79**********9988764 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0       1.6   4.4e+02      25      46 ..     293     314 ..     282     324 .. 0.83
   2 ?    4.5   0.0       0.1        29      17      47 ..     621     650 ..     614     664 .. 0.70
   3 ?    2.0   0.0      0.61   1.7e+02      25      39 ..    1064    1078 ..    1054    1093 .. 0.85
   4 ?    2.7   0.0      0.38   1.1e+02      23      43 ..    1352    1372 ..    1344    1378 .. 0.82
   5 ?    4.8   0.1     0.081        23      24      44 ..    1737    1757 ..    1729    1771 .. 0.77
   6 ?    3.3   0.0      0.24        68      26      39 ..    2047    2060 ..    2038    2066 .. 0.84

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 1.6
      AAA_29  25 tlltGpsGsGKSTllDAiqalL 46 
                  ll+G   sGK++l+  i+ ++
  EEA22601.1 293 LLLVGLPNSGKTSLVNDIAKIM 314
                 79************97776665 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.1
      AAA_29  17 ieidlkgatlltGpsGsGKSTllDAiqalLv 47 
                 + +++++ +ll+G++G GK++++  ++  L+
  EEA22601.1 621 VAVQVSEPVLLVGETGIGKTAVIQQLAN-LT 650
                 556666789************9954444.44 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.61
      AAA_29   25 tlltGpsGsGKSTll 39  
                  +ll Gp+ sGK++++
  EEA22601.1 1064 ILLQGPTSSGKTSMV 1078
                  79**********998 PP

  == domain 4  score: 2.7 bits;  conditional E-value: 0.38
      AAA_29   23 gatlltGpsGsGKSTllDAiq 43  
                  + +ll+G++G GK+ +  A++
  EEA22601.1 1352 EPVLLVGETGCGKTQICQAVA 1372
                  468***********9988876 PP

  == domain 5  score: 4.8 bits;  conditional E-value: 0.081
      AAA_29   24 atlltGpsGsGKSTllDAiqa 44  
                   +ll G  G+GK+Tl+ +++ 
  EEA22601.1 1737 PILLEGSPGVGKTTLVASLAR 1757
                  4799***********966655 PP

  == domain 6  score: 3.3 bits;  conditional E-value: 0.24
      AAA_29   26 lltGpsGsGKSTll 39  
                  +l+GpsG GK+T +
  EEA22601.1 2047 ILVGPSGCGKTTTI 2060
                  79**********87 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.0      0.33        93       2      20 ..     293     311 ..     292     332 .. 0.86
   2 ?    7.1   0.0     0.021         6       2      26 ..     629     653 ..     628     668 .. 0.86
   3 ?    0.2   0.0       2.9   8.4e+02       2      21 ..    1064    1083 ..    1064    1095 .. 0.84
   4 ?    4.6   0.0      0.13        36       2      21 ..    1354    1373 ..    1353    1403 .. 0.80
   5 ?    2.0   0.0      0.78   2.2e+02       2      20 ..    1738    1756 ..    1737    1765 .. 0.86
   6 ?    2.0   0.0      0.84   2.4e+02       3      23 ..    2047    2067 ..    2046    2098 .. 0.79

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.33
                 EEEESSTTSSHHHHHHCHC CS
         Roc   2 vvlvGdsgvGKtsllkrfv 20 
                 ++lvG  ++GKtsl++ + 
  EEA22601.1 293 LLLVGLPNSGKTSLVNDIA 311
                 689************9876 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.021
                 EEEESSTTSSHHHHHHCHCT-CCC- CS
         Roc   2 vvlvGdsgvGKtsllkrfvedkfse 26 
                 v+lvG++g+GKt  ++++ + + ++
  EEA22601.1 629 VLLVGETGIGKTAVIQQLANLTCQK 653
                 79****************9987765 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 2.9
                  EEEESSTTSSHHHHHHCHCT CS
         Roc    2 vvlvGdsgvGKtsllkrfve 21  
                  ++l G +++GKts+++ + +
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAK 1083
                  57889*********998765 PP

  == domain 4  score: 4.6 bits;  conditional E-value: 0.13
                  EEEESSTTSSHHHHHHCHCT CS
         Roc    2 vvlvGdsgvGKtsllkrfve 21  
                  v+lvG++g GKt +++ + e
  EEA22601.1 1354 VLLVGETGCGKTQICQAVAE 1373
                  79*************98876 PP

  == domain 5  score: 2.0 bits;  conditional E-value: 0.78
                  EEEESSTTSSHHHHHHCHC CS
         Roc    2 vvlvGdsgvGKtsllkrfv 20  
                  ++l G  gvGKt+l+ ++ 
  EEA22601.1 1738 ILLEGSPGVGKTTLVASLA 1756
                  56779**********9876 PP

  == domain 6  score: 2.0 bits;  conditional E-value: 0.84
                  EEESSTTSSHHHHHHCHCT-C CS
         Roc    3 vlvGdsgvGKtsllkrfvedk 23  
                  +lvG sg GKt+ ++ + + +
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLASIQ 2067
                  79**********999887655 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.6   0.0    0.0016      0.45       3      21 ..     294     312 ..     293     337 .. 0.83
   2 ?    2.2   0.0      0.63   1.8e+02       2      22 ..     629     649 ..     628     675 .. 0.79
   3 ?   -0.2   0.0       3.6     1e+03       2      31 ..    1064    1097 ..    1063    1112 .. 0.74
   4 ?   -1.1   0.0       6.9     2e+03       2      21 ..    1354    1373 ..    1353    1412 .. 0.78
   5 ?    3.9   0.0      0.19        54       3      22 ..    1739    1758 ..    1737    1777 .. 0.81
   6 ?    1.6   0.0      0.99   2.8e+02       3      21 ..    2047    2065 ..    2046    2083 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.0016
                 EEEESTTSSHHHHHHHHHT CS
    MMR_HSR1   3 aivGrpNvGKStLinaltg 21 
                 ++vG pN+GK++L+n + +
  EEA22601.1 294 LLVGLPNSGKTSLVNDIAK 312
                 69*************9975 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.63
                 EEEEESTTSSHHHHHHHHHTS CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltge 22 
                 v++vG +  GK+ +i++l + 
  EEA22601.1 629 VLLVGETGIGKTAVIQQLANL 649
                 789***************983 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 3.6
                  EEEEESTTSSHHHHHHHHHT....STEEESSSTT CS
    MMR_HSR1    2 vaivGrpNvGKStLinaltg....ekaivsdkpg 31  
                  +++ G + +GK++++  l +    + ++++++  
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAKvsgnKFVRINNHEH 1097
                  5788**************8633322456666555 PP

  == domain 4  score: -1.1 bits;  conditional E-value: 6.9
                  EEEEESTTSSHHHHHHHHHT CS
    MMR_HSR1    2 vaivGrpNvGKStLinaltg 21  
                  v++vG +  GK+ + +a  +
  EEA22601.1 1354 VLLVGETGCGKTQICQAVAE 1373
                  789**********9999875 PP

  == domain 5  score: 3.9 bits;  conditional E-value: 0.19
                  EEEESTTSSHHHHHHHHHTS CS
    MMR_HSR1    3 aivGrpNvGKStLinaltge 22  
                  ++ G p vGK+tL+ +l ++
  EEA22601.1 1739 LLEGSPGVGKTTLVASLARA 1758
                  6779************9875 PP

  == domain 6  score: 1.6 bits;  conditional E-value: 0.99
                  EEEESTTSSHHHHHHHHHT CS
    MMR_HSR1    3 aivGrpNvGKStLinaltg 21  
                  ++vG +  GK+t i++l  
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLAS 2065
                  58**************975 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.0       2.1   5.9e+02       5      27 ..     293     321 ..     289     344 .. 0.77
   2 ?    3.4   0.0      0.19        55       5      22 ..     629     646 ..     626     703 .. 0.86
   3 ?   -1.3   0.0       5.3   1.5e+03       5      27 ..    1064    1090 ..    1062    1120 .. 0.78
   4 ?   -0.8   0.0       3.8   1.1e+03       5      22 ..    1354    1371 ..    1350    1394 .. 0.84
   5 ?    6.7   0.0     0.019       5.3       3      23 ..    1736    1759 ..    1734    1773 .. 0.83
   6 ?    6.6   0.0      0.02       5.8       6      23 ..    2047    2068 ..    2042    2113 .. 0.76

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 2.1
      AAA_24   5 iliyGpsgiGKTtlakel......gpkpl 27 
                 +l++G + +GKT+l++ +      gp+ +
  EEA22601.1 293 LLLVGLPNSGKTSLVNDIakimgqGPSMV 321
                 789***********999866665555555 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.19
      AAA_24   5 iliyGpsgiGKTtlakel 22 
                 +l++G+ giGKT ++ +l
  EEA22601.1 629 VLLVGETGIGKTAVIQQL 646
                 799************999 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 5.3
      AAA_24    5 iliyGpsgiGKTtlakel....gpkpl 27  
                  il+ Gp  +GKT+++  l    g+k++
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLakvsGNKFV 1090
                  7899**********9988666655555 PP

  == domain 4  score: -0.8 bits;  conditional E-value: 3.8
      AAA_24    5 iliyGpsgiGKTtlakel 22  
                  +l++G+ g GKT ++   
  EEA22601.1 1354 VLLVGETGCGKTQICQAV 1371
                  799*********988765 PP

  == domain 5  score: 6.7 bits;  conditional E-value: 0.019
      AAA_24    3 lkiliyGpsgiGKTtlakel...g 23  
                  + il+ G++g+GKTtl+++l    
  EEA22601.1 1736 KPILLEGSPGVGKTTLVASLaraL 1759
                  568999************994443 PP

  == domain 6  score: 6.6 bits;  conditional E-value: 0.02
      AAA_24    6 liyGpsgiGKTtlakel....g 23  
                  +++Gpsg GKTt++++l    g
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLasiqG 2068
                  689************9966553 PP

>> CbiA  CobQ/CobB/MinD/ParA nucleotide binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.1   0.0   0.00054      0.15       7      34 ..    1743    1770 ..    1738    1948 .. 0.89
   2 !    9.3   0.1    0.0039       1.1       6     102 ..    2050    2174 ..    2046    2182 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00054
                  STTSSHHHHHHHHHHHHHHTT--EEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        CbiA    7 kGGvGKTtlaanLaralarrglrVllvD 34  
                  + GvGKTtl+a+Laral +   r+ l D
  EEA22601.1 1743 SPGVGKTTLVASLARALGKPLTRINLSD 1770
                  569**************99777776666 PP

  == domain 2  score: 9.3 bits;  conditional E-value: 0.0039
                  SSTTSSHHHHHHHHHHHHHHTT--EEEEEEEESSCCCCH..HTTEB-HHHH...................................CCHCCCHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxx...................................xxxxxxxxxxx RF
        CbiA    6 tkGGvGKTtlaanLaralarrglrVllvDaDpqannlai..leglendiep...................................dlkrllellea 65  
                  + +G GKTt+  +La +    +l  l++ aD+++  l i  +e+                                          dl  + +++++
  EEA22601.1 2050 GPSGCGKTTTIRTLASIQGA-ELVELALSADTDTMDL-IggFEQ------IdyrrqtqslakdvvnfihrqiissvtsestssgisDLLEIYRVCSH 2138
                  679*************8887.8888888888884443.333222......12334579*************************************99 PP

                  HCHCHHHH..EEEEEEEEESS...-TTCHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        CbiA   66 lgkkkalllkiagvvlnrvdgeneetllkealeelkq 102 
                   +++++ l + +  + +r+dg+ ++++l + ++ l q
  EEA22601.1 2139 SDINTETLANAINALQTRFDGP-TFNNLAQRCTALVQ 2174
                  99999999*************9.79999998888765 PP

>> MCM  MCM P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.0       0.1        29      57     151 ..     290     390 ..     262     396 .. 0.79
   2 ?    3.3   0.0      0.13        38      59      84 ..     628     653 ..     605     669 .. 0.76
   3 ?   -0.7   0.0       2.2   6.3e+02      59     133 ..    1063    1140 ..    1047    1154 .. 0.71
   4 !    9.8   0.0    0.0013      0.38      53      89 ..    1347    1383 ..    1336    1391 .. 0.89
   5 ?   -0.8   0.0       2.3   6.5e+02      58      98 ..    1736    1775 ..    1724    1784 .. 0.76

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.1
                 S-EEEEEESSTSTHHHHHHHHHHHSSSE....EEEESSSSSSSHSSSEEEEESSSSSEEEEETHHHHTT.TS.EEEEESGGGSTCHHHHHHHHHHHHSE CS
         MCM  57 dinvllvgdpgtaKsqlLkyveklapra....vytsgkgssaagLtaavvrdeetgefvleaGalvlad.kG.vcciDefdkmkeedrsalhEamEqqt 149
                 +  +llvg p  +K+ l++ ++k++ ++    +    +++ a  L  +   ++ tg f  + G l  a  +G  ++i ++d+  +e    ++ ++E+ +
  EEA22601.1 290 QKPLLLVGLPNSGKTSLVNDIAKIMGQGpsmvTLHLNEQTDAKSLLGMYATSSLTGTFSWQPGVLTKAAkEGrWILIEDLDRAPSEVIGLMLPVIEKGE 388
                 55689*****************99866521112334567778899999999**************987514646899****999988888888888877 PP

                 EE CS
         MCM 150 is 151
                 + 
  EEA22601.1 389 LI 390
                 65 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.13
                 EEEEEESSTSTHHHHHHHHHHHSSSE CS
         MCM  59 nvllvgdpgtaKsqlLkyveklapra 84 
                  vllvg+ g++K+++++++++l+ + 
  EEA22601.1 628 PVLLVGETGIGKTAVIQQLANLTCQK 653
                 59****************99766543 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 2.2
                  EEEEEESSTSTHHHHHHHHHHHSSSEEEEESSSSSSSHSSSEEEEESSSSS..EEEEETHHHHT.TTS.EEEEESGGGS CS
         MCM   59 nvllvgdpgtaKsqlLkyveklapravytsgkgssaagLtaavvrdeetge..fvleaGalvla.dkG.vcciDefdkm 133 
                   +ll g  + +K+ +++y++k+ + + ++ ++   +++L  +     +t++  +  + G lv a  +G  +++De++  
  EEA22601.1 1063 PILLQGPTSSGKTSMVEYLAKV-SGNKFVRINNHEHTDLQEYLGSYVSTDDgsLKYQEGVLVEAlRNGyWIVLDELNLA 1140
                  6999***************965.57788888888888876665544444332267788999987434524677888755 PP

  == domain 4  score: 9.8 bits;  conditional E-value: 0.0013
                  BBCSS-EEEEEESSTSTHHHHHHHHHHHSSSEEEEES CS
         MCM   53 klrgdinvllvgdpgtaKsqlLkyveklapravytsg 89  
                   lr +  vllvg+ g++K+q+ ++v+++  + +y+  
  EEA22601.1 1347 ALRNNEPVLLVGETGCGKTQICQAVAEIYGKEMYIVN 1383
                  5788999**********************99999865 PP

  == domain 5  score: -0.8 bits;  conditional E-value: 2.3
                  -EEEEEESSTSTHHHHHHHHHHHSSSEEEEESSSSSSSHSS CS
         MCM   58 invllvgdpgtaKsqlLkyveklapravytsgkgssaagLt 98  
                    +ll g pg++K++l+ ++++ +     t ++ s +++Lt
  EEA22601.1 1736 KPILLEGSPGVGKTTLVASLARAL-GKPLTRINLSDQTDLT 1775
                  5699************99998544.4445566666665555 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.1       2.5   7.2e+02       2      22 ..     629     649 ..     628     659 .. 0.81
   2 ?    4.9   0.0       0.1        29       2      23 ..    1064    1086 ..    1063    1119 .. 0.72
   3 ?    0.7   0.0         2   5.7e+02       2      22 ..    1354    1374 ..    1353    1396 .. 0.83
   4 !    8.8   0.1    0.0061       1.7       2      22 ..    1738    1758 ..    1737    1766 .. 0.86
   5 !    9.9   0.3    0.0028       0.8       3      27 ..    2047    2072 ..    2046    2078 .. 0.84

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 2.5
      AAA_28   2 ivitGgestGKTtlleaLaar 22 
                 + ++G  + GKT ++++La+ 
  EEA22601.1 629 VLLVGETGIGKTAVIQQLANL 649
                 6789999************75 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.1
      AAA_28    2 ivitGgestGKTtlleaLaar.g 23  
                  i + G+ s+GKT+++e La+  g
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAKVsG 1086
                  7789***************5433 PP

  == domain 3  score: 0.7 bits;  conditional E-value: 2
      AAA_28    2 ivitGgestGKTtlleaLaar 22  
                  + ++G  ++GKT +++a a+ 
  EEA22601.1 1354 VLLVGETGCGKTQICQAVAEI 1374
                  6789999**********9974 PP

  == domain 4  score: 8.8 bits;  conditional E-value: 0.0061
      AAA_28    2 ivitGgestGKTtlleaLaar 22  
                  i + G ++ GKTtl++ La+ 
  EEA22601.1 1738 ILLEGSPGVGKTTLVASLARA 1758
                  7899***************76 PP

  == domain 5  score: 9.9 bits;  conditional E-value: 0.0028
      AAA_28    3 vitGgestGKTtlleaLaar.gypvv 27  
                  +++G++++GKTt+++ La+  g + v
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLASIqGAELV 2072
                  689***************84466655 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.0     0.054        15      21      51 ..     621     653 ..     590     711 .. 0.83
   2 ?   -0.4   0.0       3.6     1e+03      12      41 ..    1050    1078 ..    1042    1089 .. 0.78
   3 ?    6.4   0.0     0.028       7.9      21      52 ..    1342    1379 ..    1292    1394 .. 0.77
   4 ?    1.8   0.0      0.76   2.2e+02      22      48 ..    1733    1759 ..    1716    1767 .. 0.81

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.054
                 ....TTSEEEEEESTTSTHHHHHHHHHHHH-S. CS
      ResIII  21 s..krdkrglikmaTGtGKTlvaaklierllkk 51 
                    +  + +l++ +TG GKT v+ +l+    +k
  EEA22601.1 621 VavQVSEPVLLVGETGIGKTAVIQQLANLTCQK 653
                 255677899*************99998877766 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 3.6
                  HHHHT......TTSEEEEEESTTSTHHHHH CS
      ResIII   12 ienlleklkskrdkrglikmaTGtGKTlva 41  
                  ++nll + + +r+  +l++ +T +GKT + 
  EEA22601.1 1050 LKNLLRASS-TRRFPILLQGPTSSGKTSMV 1078
                  455554444.8999*************886 PP

  == domain 3  score: 6.4 bits;  conditional E-value: 0.028
                  ........TTSEEEEEESTTSTHHHHHHHHHHHH-S.. CS
      ResIII   21 s......krdkrglikmaTGtGKTlvaaklierllkkg 52  
                         ++++ +l++ +TG+GKT ++ +++e + k+ 
  EEA22601.1 1342 VlvsealRNNEPVLLVGETGCGKTQICQAVAEIYGKEM 1379
                  04444557999***************999888877665 PP

  == domain 4  score: 1.8 bits;  conditional E-value: 0.76
                  .TTSEEEEEESTTSTHHHHHHHHHHHH CS
      ResIII   22 krdkrglikmaTGtGKTlvaaklierl 48  
                  +  k +l++   G+GKT + a+l+++l
  EEA22601.1 1733 QTSKPILLEGSPGVGKTTLVASLARAL 1759
                  6788999***************99887 PP

>> Bac_DnaA  Bacterial dnaA  protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.0      0.01       2.9      18      61 ..     611     653 ..     603     663 .. 0.79
   2 ?    5.6   0.0     0.044        12      30      56 ..    1347    1373 ..    1332    1386 .. 0.81
   3 ?    2.3   0.0      0.45   1.3e+02      26      57 ..    1728    1758 ..    1713    1767 .. 0.75

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.01
                 HHHHHHHHHHHSTTT.S--EEEE-SSSSSHHHHHHHHHHHHHHH CS
    Bac_DnaA  18 lAlaaalkvaeapgkkynPlfiygevGlGktHLlkaignevlen 61 
                  Al+   ++a a +    P+++ ge+G+Gkt +++ ++n + ++
  EEA22601.1 611 AALKTMEQIAVAVQV-SEPVLLVGETGIGKTAVIQQLANLTCQK 653
                 455666666655544.79*******************9988765 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.044
                  TTT.S--EEEE-SSSSSHHHHHHHHHH CS
    Bac_DnaA   30 pgkkynPlfiygevGlGktHLlkaign 56  
                  + ++  P+++ ge+G Gkt + +a++ 
  EEA22601.1 1347 ALRNNEPVLLVGETGCGKTQICQAVAE 1373
                  445678******************986 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.45
                  HHHSTTT.S--EEEE-SSSSSHHHHHHHHHHH CS
    Bac_DnaA   26 vaeapgkkynPlfiygevGlGktHLlkaigne 57  
                  +a   + +  P+++ g+ G+Gkt L+ +++ +
  EEA22601.1 1728 IARGLQ-TSKPILLEGSPGVGKTTLVASLARA 1758
                  444333.468****************999876 PP

>> SRPRB  Signal recognition particle receptor beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   0.0     0.031       8.8       3      23 ..     290     310 ..     289     331 .. 0.86
   2 ?    3.9   0.0      0.11        32       4      39 ..     627     665 ..     624     703 .. 0.77
   3 ?    2.0   0.0      0.42   1.2e+02       6      25 ..    1064    1083 ..    1059    1100 .. 0.84
   4 ?   -0.1   0.0       1.9   5.3e+02       3      21 ..    1351    1369 ..    1349    1380 .. 0.85
   5 ?    0.9   0.0      0.92   2.6e+02       7      24 ..    2047    2064 ..    2043    2081 .. 0.87

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.031
                 --EEEEE-STTSSHHHHHHHH CS
       SRPRB   3 kpavllvGlsdsGKTslftrL 23 
                 ++ +llvGl +sGKTsl + +
  EEA22601.1 290 QKPLLLVGLPNSGKTSLVNDI 310
                 56689************9976 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.11
                 -EEEEE-STTSSHHHHHHHHHHSS---.B--..-SS-EE CS
       SRPRB   4 pavllvGlsdsGKTslftrLttdsvkk.tvt..Sqessa 39 
                 + vllvG +  GKT+++++L + + +k tv+  Sq+s++
  EEA22601.1 627 EPVLLVGETGIGKTAVIQQLANLTCQKlTVVnlSQQSES 665
                 569***************998775443144411554444 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.42
                  EEEE-STTSSHHHHHHHHHH CS
       SRPRB    6 vllvGlsdsGKTslftrLtt 25  
                  +ll G++ sGKTs+ + L +
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAK 1083
                  899***********998876 PP

  == domain 4  score: -0.1 bits;  conditional E-value: 1.9
                  --EEEEE-STTSSHHHHHH CS
       SRPRB    3 kpavllvGlsdsGKTslft 21  
                  ++ vllvG + +GKT + +
  EEA22601.1 1351 NEPVLLVGETGCGKTQICQ 1369
                  5679***********9866 PP

  == domain 5  score: 0.9 bits;  conditional E-value: 0.92
                  EEE-STTSSHHHHHHHHH CS
       SRPRB    7 llvGlsdsGKTslftrLt 24  
                  +lvG+s +GKT+ +  L 
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLA 2064
                  89*********9988886 PP

>> TIP49  TIP49 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0      0.55   1.6e+02      48      81 ..     288     321 ..     275     328 .. 0.83
   2 ?    0.3   0.1       1.1   3.1e+02      49      81 ..     626     657 ..     602     664 .. 0.73
   3 ?   -1.6   0.0       4.1   1.2e+03      53      75 ..    1064    1086 ..    1051    1096 .. 0.77
   4 ?    4.3   0.0     0.068        19      33      80 ..    1338    1381 ..    1314    1388 .. 0.73
   5 ?    6.5   0.0     0.014         4      49      78 ..    1734    1763 ..    1718    1774 .. 0.81

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.55
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49  48 laGravLlaGpsgtGktalaiaiskelgedvpfv 81 
                 l  + +Ll+G + +Gkt+l   i+k +g+    v
  EEA22601.1 288 LEQKPLLLVGLPNSGKTSLVNDIAKIMGQGPSMV 321
                 556889*******************999875555 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 1.1
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49  49 aGravLlaGpsgtGktalaiaiskelgedvpfv 81 
                 +   vLl+G++g Gkta+   +++   +++  v
  EEA22601.1 626 S-EPVLLVGETGIGKTAVIQQLANLTCQKLTVV 657
                 4.679************9888777666666555 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 4.1
                  XXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49   53 vLlaGpsgtGktalaiaiskelg 75  
                  +Ll+Gp+++Gkt++   ++k  g
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAKVSG 1086
                  9***********99877777655 PP

  == domain 4  score: 4.3 bits;  conditional E-value: 0.068
                  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49   33 reaagvivelikekklaGravLlaGpsgtGktalaiaiskelgedvpf 80  
                  r+   ++ e ++        vLl+G++g Gkt +  a+++  g+++  
  EEA22601.1 1338 RRVFVLVSEALR----NNEPVLLVGETGCGKTQICQAVAEIYGKEMYI 1381
                  444444444444....44589******************999988765 PP

  == domain 5  score: 6.5 bits;  conditional E-value: 0.014
                  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49   49 aGravLlaGpsgtGktalaiaiskelgedv 78  
                  + + +Ll G +g Gkt l  +++++lg+ +
  EEA22601.1 1734 TSKPILLEGSPGVGKTTLVASLARALGKPL 1763
                  4589***********************744 PP

>> CPT  Chloramphenicol phosphotransferase-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0         2   5.7e+02       5      25 ..     294     314 ..     291     323 .. 0.87
   2 !    9.5   0.0    0.0029      0.84       4      35 ..    1064    1095 ..    1063    1160 .. 0.83
   3 ?    1.5   0.0      0.83   2.4e+02       4      32 ..    1738    1766 ..    1735    1775 .. 0.85

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 2
                 EEEE-TTSSHHHHHHHHHHHS CS
         CPT   5 lLnGgsssGKsslaralqevl 25 
                 lL G + sGK+sl++ + +++
  EEA22601.1 294 LLVGLPNSGKTSLVNDIAKIM 314
                 899***********9998876 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.0029
                  EEEEE-TTSSHHHHHHHHHHHSSS-EEEEEHH CS
         CPT    4 ilLnGgsssGKsslaralqevldepwlhlgvD 35  
                  ilL+G +ssGK+s+++ l +v+ + ++ ++  
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAKVSGNKFVRINNH 1095
                  89********************9999988755 PP

  == domain 3  score: 1.5 bits;  conditional E-value: 0.83
                  EEEEE-TTSSHHHHHHHHHHHSSS-EEEE CS
         CPT    4 ilLnGgsssGKsslaralqevldepwlhl 32  
                  ilL+G++  GK++l+  l   l +p   +
  EEA22601.1 1738 ILLEGSPGVGKTTLVASLARALGKPLTRI 1766
                  9**************99999888887655 PP

>> Viral_helicase1  Viral (Superfamily 1) RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0       2.5   7.1e+02       7      34 ..     635     656 ..     630     692 .. 0.71
   2 ?   -0.0   0.0       2.1     6e+02       6      20 ..    1359    1373 ..    1355    1392 .. 0.81
   3 ?    4.5   0.0     0.088        25       2      23 ..    1739    1761 ..    1738    1833 .. 0.71
   4 ?    5.4   0.0     0.046        13       5      22 ..    2050    2067 ..    2046    2104 .. 0.81

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 2.5
  Viral_helicase1   7 pGcGKStlirkllrts.liltvnrptael 34 
                       G GK+ +i++l++    +lt       +
       EEA22601.1 635 TGIGKTAVIQQLANLTcQKLT-------V 656
                      688**********99552222.......2 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 2.1
  Viral_helicase1    6 vpGcGKStlirkllr 20  
                         GcGK+++++ +++
       EEA22601.1 1359 ETGCGKTQICQAVAE 1373
                       57*******999875 PP

  == domain 3  score: 4.5 bits;  conditional E-value: 0.088
  Viral_helicase1    2 vvhGvpGcGKStlirkllrts.l 23  
                       +  G pG GK+tl+ +l+r    
       EEA22601.1 1739 LLEGSPGVGKTTLVASLARALgK 1761
                       67899*************99552 PP

  == domain 4  score: 5.4 bits;  conditional E-value: 0.046
  Viral_helicase1    5 GvpGcGKStlirkllrts 22  
                       G  GcGK+t ir+l++ +
       EEA22601.1 2050 GPSGCGKTTTIRTLASIQ 2067
                       556***********9764 PP

>> DnaB_C  DnaB-like helicase C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0       2.7   7.7e+02      11      45 ..     282     316 ..     274     341 .. 0.75
   2 ?    1.2   0.1      0.66   1.9e+02       6      60 ..     613     665 ..     610     672 .. 0.80
   3 ?    2.4   0.0      0.29        84      15     100 ..    1347    1437 ..    1343    1468 .. 0.75
   4 !    7.8   0.1    0.0063       1.8      12      42 ..    1728    1758 ..    1720    1769 .. 0.90

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 2.7
                 HHCTSBXTTXEEEEEEXTTSSHHHHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      DnaB_C  11 kltsGlqkgdliiiAarpsmGktalalniaenaav 45 
                 ++ + l +++ +++ + p  Gkt+l+ +ia+ + +
  EEA22601.1 282 SVANALLEQKPLLLVGLPNSGKTSLVNDIAKIMGQ 316
                 55666666667788899*************97654 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.66
                 THHHHHHCTSBXTTXEEEEEEXTTSSHHHHHHHHHHHHHHCSTSEEEEEESSSXH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      DnaB_C   6 fkdLDkltsGlqkgdliiiAarpsmGktalalniaenaavkeklpvavfslemsa 60 
                 +k+++++   +q ++ +++ +  ++Gkta+  ++a+ +++  kl+v+  s   ++
  EEA22601.1 613 LKTMEQIAVAVQVSEPVLLVGETGIGKTAVIQQLANLTCQ--KLTVVNLSQQSES 665
                 5678889999999**********************98775..5666666655555 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.29
                  SBXTTXEEEEEEXTTSSHHHHHHHHHHHHHHCSTSEEEEEESSSXHHHHHHHHHHHHHTXXHHHHHH.....TTSXHHHHHHHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxx RF
      DnaB_C   15 GlqkgdliiiAarpsmGktalalniaenaavkeklpvavfslemsaeqlvqRllsseaeidskklrt.....gklkeedweklteaieels 100 
                   l++++ +++ +  ++Gkt ++  +ae   ++  +  a ++le  +   +qR l +++ i+ + +       ++l ++++++ ++++++l+
  EEA22601.1 1347 ALRNNEPVLLVGETGCGKTQICQAVAEIYGKEMYIVNAHVNLETGDIVGAQRPLRNRSAIERQLCDDlasviSTLPDAEIDQSSKSLDNLK 1437
                  57788889999****************98887778889999**999999**********99887644222324455555555555555554 PP

  == domain 4  score: 7.8 bits;  conditional E-value: 0.0063
                  HCTSBXTTXEEEEEEXTTSSHHHHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      DnaB_C   12 ltsGlqkgdliiiAarpsmGktalalniaen 42  
                  + +Glq ++ i++ + p++Gkt+l+ ++a++
  EEA22601.1 1728 IARGLQTSKPILLEGSPGVGKTTLVASLARA 1758
                  678************************9986 PP

>> KTI12  Chromatin associated protein KTI12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.0     0.033       9.3       5      40 ..     294     329 ..     292     342 .. 0.84
   2 ?   -2.3   0.0       8.1   2.3e+03       4      28 ..    1064    1088 ..    1064    1138 .. 0.66
   3 ?    3.9   0.0      0.11        30       4      39 ..    1738    1773 ..    1737    1817 .. 0.69
   4 ?   -1.7   0.3       5.3   1.5e+03     216     270 ..    2418    2472 ..    2405    2474 .. 0.72

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.033
                 EEE--TTSSHHHHHHHHHHHHHHTT--EEEE-THHH CS
       KTI12   5 vltGlPssGKstrakeLakaleeekrsvvviddesl 40 
                 +l GlP sGK+++++ +ak + +    v+++ +e+ 
  EEA22601.1 294 LLVGLPNSGKTSLVNDIAKIMGQGPSMVTLHLNEQT 329
                 789*****************9998888888777765 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 8.1
                  EEEE--TTSSHHHHHHHHHHHHHHT CS
       KTI12    4 vvltGlPssGKstrakeLakaleee 28  
                  ++l G  ssGK+++++ Lak   ++
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAKVSGNK 1088
                  7899999*********999865443 PP

  == domain 3  score: 3.9 bits;  conditional E-value: 0.11
                  EEEE--TTSSHHHHHHHHHHHHHHTT--EEEE-THH CS
       KTI12    4 vvltGlPssGKstrakeLakaleeekrsvvviddes 39  
                  ++l G P +GK+t+++ La+al +   ++ + d+  
  EEA22601.1 1738 ILLEGSPGVGKTTLVASLARALGKPLTRINLSDQTD 1773
                  7899******************99777776666544 PP

  == domain 4  score: -1.7 bits;  conditional E-value: 5.3
                  --HHH................HHHHHHHHHHHHHHHT.TSSS--HHHHHHHHHHH CS
       KTI12  216 idkltlpgsseslelpakkltlaeLsrlrrqFvklnkaklenvdeekiaklFvdy 270 
                   +  +l ++  + ++ +++l+ +++ rl r+F +   ++l + d++ +    +d+
  EEA22601.1 2418 LSLHKLQQRLAHSHQNSQHLKPSQMTRLERSFASSRISSLMKDDTQAVSSFLTDF 2472
                  4556677888888999999999999999999999888666666666665555555 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0       1.4     4e+02      20      46 ..     627     653 ..     616     676 .. 0.78
   2 ?    3.4   0.0      0.15        42      15      37 ..    1347    1369 ..    1341    1373 .. 0.85
   3 ?    4.8   0.0     0.054        15      13      37 ..    1729    1753 ..    1718    1757 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 1.4
      ATPase  20 rvvlitGepGtGKtifalqFlikgaek 46 
                 + vl++Ge+G GKt + +q +   ++k
  EEA22601.1 627 EPVLLVGETGIGKTAVIQQLANLTCQK 653
                 679***********9999977666655 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.15
      ATPase   15 GipegrvvlitGepGtGKtifal 37  
                   + +++ vl++Ge+G+GKt +++
  EEA22601.1 1347 ALRNNEPVLLVGETGCGKTQICQ 1369
                  5778899************9886 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.054
      ATPase   13 kgGipegrvvlitGepGtGKtifal 37  
                   +G+   + +l+ G+pG GKt++++
  EEA22601.1 1729 ARGLQTSKPILLEGSPGVGKTTLVA 1753
                  5899*****************9975 PP

>> KAP_NTPase  KAP family P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0      0.18        51       6      45 ..    1048    1086 ..    1044    1197 .. 0.69
   2 ?   -2.4   0.0       7.9   2.2e+03      12      43 ..    1343    1374 ..    1341    1447 .. 0.87
   3 ?    6.3   0.0     0.017       4.8      17      73 ..    1732    1896 ..    1721    1919 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.18
  KAP_NTPase    6 saladilseptlatpivvgLygkWGsGKssllnkledelk 45  
                  ++l ++l  ++ ++ +++ L+g+  sGK+s+++ l +   
  EEA22601.1 1048 KNLKNLLRASS-TRRFPILLQGPTSSGKTSMVEYLAKVSG 1086
                  78999999886.********************99887554 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 7.9
  KAP_NTPase   12 lseptlatpivvgLygkWGsGKssllnklede 43  
                  l++ +l++  +v L g+ G+GK+ +++ + + 
  EEA22601.1 1343 LVSEALRNNEPVLLVGETGCGKTQICQAVAEI 1374
                  667778888899999*********99987665 PP

  == domain 3  score: 6.3 bits;  conditional E-value: 0.017
  KAP_NTPase   17 latpivvgLygkWGsGKssllnkledelkefa................................................................. 48  
                  l+t+ ++ L+g  G+GK++l+++l ++l +                                                                   
  EEA22601.1 1732 LQTSKPILLEGSPGVGKTTLVASLARALGKPLtrinlsdqtdltdlfgsdvpveggdagqfawrdapflqamqkgdwvlldemnlasqsvleglnsc 1828
                  578889*********************9998888899999999999999999999999999999999999999999999999999999999999999 PP

  KAP_NTPase   49 ...........................................kpvrflfaefnawsfkggddavael 73  
                                                               +rf++++++++s ++ +++  +l
  EEA22601.1 1829 ldhrqqvyvaeldqtfkrhpdfvlfaaqnphhqgggrkglpasFVNRFTVVYADSFSDTDLNSICSKL 1896
                  99999999999999999999999999999999999999988886678999999998887744444443 PP

>> PhoH  PhoH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.2   0.0      0.74   2.1e+02      12      98 ..     619     703 ..     610     709 .. 0.59
   2 ?    7.1   0.0     0.012       3.4      13      40 ..    1345    1372 ..    1338    1435 .. 0.74
   3 ?   -1.5   0.0         5   1.4e+03      23      35 ..    2047    2059 ..    2037    2074 .. 0.77

  Alignments for each domain:
  == domain 1  score: 1.2 bits;  conditional E-value: 0.74
                 HHHHHHH-SEEEEE--TTSSTTHHHHHHHHHHHHTTS-SEEEEEE-S--TT----SS---------TTTHHHHHHHTTTS-TTCHHH CS
        PhoH  12 ylealkkndivfaiGpaGtGKtylavalavealkkkkvkriiltrpaveageelGflpgdleekvdpylrplydaLkdllgaekvek 98 
                 ++ a++ ++ v  +G++G GKt +  +la   l+ +k++ + l++ + + +   Gf p +l+    p l  + +  +++++a+k +k
  EEA22601.1 619 IAVAVQVSEPVLLVGETGIGKTAVIQQLA--NLTCQKLTVVNLSQQSESTDLLGGFRPVNLRSMAIPLLDEFNQLFESTFSAKKNQK 703
                 4445667778999*********6644444..44444444444444444434444566666666666666666666666666665555 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.012
                  HHHHHH-SEEEEE--TTSSTTHHHHHHH CS
        PhoH   13 lealkkndivfaiGpaGtGKtylavala 40  
                   eal++n+ v  +G++G+GKt +  a+a
  EEA22601.1 1345 SEALRNNEPVLLVGETGCGKTQICQAVA 1372
                  68999****************9876655 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 5
                  EEE--TTSSTTHH CS
        PhoH   23 faiGpaGtGKtyl 35  
                  + +Gp+G+GKt  
  EEA22601.1 2047 ILVGPSGCGKTTT 2059
                  689*******964 PP

>> dNK  Deoxynucleoside kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.0      0.13        38       1      31 [.    1064    1094 ..    1064    1128 .. 0.80
   2 ?    4.8   0.0     0.077        22       1      23 [.    1738    1760 ..    1738    1771 .. 0.89
   3 ?   -1.0   0.1       4.6   1.3e+03       5      26 ..    2050    2071 ..    2047    2075 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.13
                  EEEEESTTSSHHHHHHHHHCCSTCEEEE-HH CS
         dNK    1 ivveGnIgaGKstlvklLskklgvkvfeEpv 31  
                  i ++G+ ++GK+++v+ L+k  g k+++  +
  EEA22601.1 1064 ILLQGPTSSGKTSMVEYLAKVSGNKFVRINN 1094
                  6789*****************9977776444 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.077
                  EEEEESTTSSHHHHHHHHHCCST CS
         dNK    1 ivveGnIgaGKstlvklLskklg 23  
                  i +eG  g+GK+tlv  L+++lg
  EEA22601.1 1738 ILLEGSPGVGKTTLVASLARALG 1760
                  679****************9997 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 4.6
                  ESTTSSHHHHHHHHHCCSTCEE CS
         dNK    5 GnIgaGKstlvklLskklgvkv 26  
                  G+ g+GK+t + +L+   g + 
  EEA22601.1 2050 GPSGCGKTTTIRTLASIQGAEL 2071
                  888***********99877665 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0       4.3   1.2e+03       3      22 ..     630     649 ..     629     703 .. 0.75
   2 ?    9.4   0.0    0.0029      0.81       3      26 ..    2047    2075 ..    2046    2112 .. 0.74

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 4.3
      AAA_21   3 vliGpNgsGKSnLLdaldll 22 
                 +l+G  g GK+ +++ l  l
  EEA22601.1 630 LLVGETGIGKTAVIQQLANL 649
                 79************988666 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.0029
      AAA_21    3 vliGpNgsGKSnLLdaldllarl.....d 26  
                  +l+Gp g+GK++ +++l  ++++     +
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLASIQGAelvelA 2075
                  79****************99987665441 PP

>> DUF927  Domain of unknown function (DUF927)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   0.0     0.018       5.1     186     255 ..    1053    1140 ..    1050    1148 .. 0.83
   2 ?    1.2   0.0      0.75   2.1e+02     199     225 ..    1356    1381 ..    1343    1386 .. 0.88
   3 ?   -0.2   0.0         2   5.8e+02     200     221 ..    2049    2070 ..    2047    2081 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.018
      DUF927  186 LLkllgaeggglhlygeSstGKttalklAaSvwGnpe............elvrswraTang....lEgla..aannDllLiLDEisea 255 
                  LL+   ++ + + l g +s+GKt +++  a v Gn              e++ s+ +T+ g     Eg++  a +n+  ++LDE++ a
  EEA22601.1 1053 LLRASSTRRFPILLQGPTSSGKTSMVEYLAKVSGNKFvrinnhehtdlqEYLGSYVSTDDGslkyQEGVLveALRNGYWIVLDELNLA 1140
                  778888888899999********************999999********77777777775433328999944579*********9765 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.75
      DUF927  199 lygeSstGKttalklAaSvwGnpeelv 225 
                  l+ge+  GKt +++++a ++G++  ++
  EEA22601.1 1356 LVGETGCGKTQICQAVAEIYGKEM-YI 1381
                  789******************998.55 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 2
      DUF927  200 ygeSstGKttalklAaSvwGnp 221 
                  +g S  GKtt+++  aS+ G +
  EEA22601.1 2049 VGPSGCGKTTTIRTLASIQGAE 2070
                  78999*************9986 PP

>> PRK  Phosphoribulokinase / Uridine kinase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0       1.8   5.1e+02       5      28 ..    1357    1380 ..    1354    1409 .. 0.79
   2 ?    8.0   0.0    0.0076       2.2       5      29 ..    2049    2073 ..    2047    2105 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 1.8
         PRK    5 agsSGaGkttvarklekifgrekv 28  
                   g+ G+Gkt + +++ +i g+e  
  EEA22601.1 1357 VGETGCGKTQICQAVAEIYGKEMY 1380
                  6999**************997653 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.0076
         PRK    5 agsSGaGkttvarklekifgrekvk 29  
                   g+SG+Gktt+ r+l +i g e v+
  EEA22601.1 2049 VGPSGCGKTTTIRTLASIQGAELVE 2073
                  699**************99977766 PP

>> ATP_bind_1  Conserved hypothetical ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.0       2.1     6e+02       2      22 ..     296     316 ..     295     325 .. 0.84
   2 ?    2.0   0.1      0.54   1.5e+02       2      32 ..     632     659 ..     631     666 .. 0.90
   3 ?   -1.2   0.1       4.9   1.4e+03       3      19 ..    1068    1084 ..    1066    1090 .. 0.86
   4 ?    6.3   0.1     0.026       7.3       2      31 ..    1357    1383 ..    1356    1391 .. 0.88
   5 ?    3.0   0.0      0.26        75       3      20 ..    1742    1759 ..    1740    1770 .. 0.79
   6 ?    1.8   0.0      0.59   1.7e+02       2      20 ..    2049    2067 ..    2048    2087 .. 0.84

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 2.1
  ATP_bind_1   2 vGpaGsGKttfvgalseilel 22 
                 vG + sGKt++v+ +++i+ +
  EEA22601.1 296 VGLPNSGKTSLVNDIAKIMGQ 316
                 7999***********999865 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.54
  ATP_bind_1   2 vGpaGsGKttfvgalseilelrgrsvavvNL 32 
                 vG  G GKt  +++l++++ ++   + vvNL
  EEA22601.1 632 VGETGIGKTAVIQQLANLTCQK---LTVVNL 659
                 899*************999888...99***9 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 4.9
  ATP_bind_1    3 GpaGsGKttfvgalsei 19  
                  Gp +sGKt++v+ l+++
  EEA22601.1 1068 GPTSSGKTSMVEYLAKV 1084
                  99*********988765 PP

  == domain 4  score: 6.3 bits;  conditional E-value: 0.026
  ATP_bind_1    2 vGpaGsGKttfvgalseilelrgrsvavvN 31  
                  vG  G GKt +++a++ei+ ++   +++vN
  EEA22601.1 1357 VGETGCGKTQICQAVAEIYGKE---MYIVN 1383
                  899***************9988...88887 PP

  == domain 5  score: 3.0 bits;  conditional E-value: 0.26
  ATP_bind_1    3 GpaGsGKttfvgalseil 20  
                  G +G+GKtt+v +l+  l
  EEA22601.1 1742 GSPGVGKTTLVASLARAL 1759
                  899*********998655 PP

  == domain 6  score: 1.8 bits;  conditional E-value: 0.59
  ATP_bind_1    2 vGpaGsGKttfvgalseil 20  
                  vGp G GKtt +++l++i 
  EEA22601.1 2049 VGPSGCGKTTTIRTLASIQ 2067
                  8*************99886 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.2      0.63   1.8e+02       2      23 ..     629     650 ..     628     659 .. 0.84
   2 ?    2.3   0.0      0.48   1.4e+02       2      26 ..    1354    1378 ..    1353    1385 .. 0.83
   3 ?    9.1   0.0    0.0041       1.2       2      23 ..    1738    1759 ..    1737    1766 .. 0.88
   4 ?    0.6   0.2       1.6   4.7e+02       3      20 ..    2047    2064 ..    2046    2071 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.63
                 EEEE--TTSSHHHHHHHHHHHH CS
    NTPase_1   2 vfiTGppGvGKtTlvkkvlell 23 
                 v++ G+ G+GKt +++++++l 
  EEA22601.1 629 VLLVGETGIGKTAVIQQLANLT 650
                 6899************998864 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.48
                  EEEE--TTSSHHHHHHHHHHHH... CS
    NTPase_1    2 vfiTGppGvGKtTlvkkvlellkss 26  
                  v++ G+ G GKt +++ v+e   ++
  EEA22601.1 1354 VLLVGETGCGKTQICQAVAEIYGKE 1378
                  6899**************9987555 PP

  == domain 3  score: 9.1 bits;  conditional E-value: 0.0041
                  EEEE--TTSSHHHHHHHHHHHH CS
    NTPase_1    2 vfiTGppGvGKtTlvkkvlell 23  
                  +++ G+pGvGKtTlv  ++++l
  EEA22601.1 1738 ILLEGSPGVGKTTLVASLARAL 1759
                  6789*************99998 PP

  == domain 4  score: 0.6 bits;  conditional E-value: 1.6
                  EEE--TTSSHHHHHHHHH CS
    NTPase_1    3 fiTGppGvGKtTlvkkvl 20  
                  ++ Gp+G GKtT ++ ++
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLA 2064
                  578*********998765 PP

>> ATP-synt_ab  ATP synthase alpha/beta family, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0      0.38   1.1e+02      17      46 ..     629     657 ..     619     988 .. 0.91
   2 ?    3.7   0.0      0.14        41      17      46 ..    1354    1383 ..    1322    1691 .. 0.88
   3 ?   -0.3   0.0       2.5   7.2e+02      17      38 ..    2046    2067 ..    2032    2413 .. 0.86
   4 ?   -2.1   0.0       8.7   2.5e+03      43      81 ..    4793    4831 ..    4755    4839 .. 0.86

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.38
                  EEEEESTTSSHHHHHHHHHHHSSTSSEEEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab  17 tlipgafgvGktvisqslskqsnsddaiiy 46 
                  +l++g+ g+Gkt+++q+l++ + ++ ++++
   EEA22601.1 629 VLLVGETGIGKTAVIQQLANLTCQK-LTVV 657
                  6789***************997665.4444 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.14
                   EEEEESTTSSHHHHHHHHHHHSSTSSEEEE CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab   17 tlipgafgvGktvisqslskqsnsddaiiy 46  
                   +l++g+ g+Gkt+i+q++++   ++ +i+ 
   EEA22601.1 1354 VLLVGETGCGKTQICQAVAEIYGKEMYIVN 1383
                   5789**************998766634444 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 2.5
                   EEEEESTTSSHHHHHHHHHHHS CS
                   xxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab   17 tlipgafgvGktvisqslskqs 38  
                    +++g +g+Gkt+ +++l+  +
   EEA22601.1 2046 SILVGPSGCGKTTTIRTLASIQ 2067
                   578999*******999998764 PP

  == domain 4  score: -2.1 bits;  conditional E-value: 8.7
                   EEEEEEESEEHHHHHHHHHHCHHSSGGGGEEEEEEETTS CS
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  ATP-synt_ab   43 aiiyvgiGergnevaevleefpegtimkrtvlvantsne 81  
                   +ii  gi e ++++++++++ +e++im   ++v + s +
   EEA22601.1 4793 LIISDGICEDHETIRRLVRQAQEERIMIVFIIVDAASGN 4831
                   788899999999999999999999999999999887765 PP

>> FeoB_N  Ferrous iron transport protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   0.0    0.0081       2.3       4      22 ..     294     312 ..     291     316 .. 0.88
   2 ?    0.2   0.1       1.7   4.7e+02       3      24 ..     629     650 ..     627     661 .. 0.82
   3 ?   -0.8   0.0       3.3   9.4e+02       3      22 ..    1354    1373 ..    1353    1383 .. 0.84
   4 ?    1.5   0.0      0.68   1.9e+02       3      22 ..    1738    1757 ..    1736    1761 .. 0.87
   5 ?   -2.1   0.1       8.7   2.5e+03       4      22 ..    2047    2065 ..    2046    2068 .. 0.86

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0081
                 EEEESTTSSHHHHHHHHHT CS
      FeoB_N   4 alvGnpnvGkttlfnaltg 22 
                  lvG pn+Gkt+l+n +++
  EEA22601.1 294 LLVGLPNSGKTSLVNDIAK 312
                 69*************9986 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 1.7
                 EEEEESTTSSHHHHHHHHHTTS CS
      FeoB_N   3 valvGnpnvGkttlfnaltgak 24 
                 v lvG+  +Gkt+++ +l++ +
  EEA22601.1 629 VLLVGETGIGKTAVIQQLANLT 650
                 789************9998754 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 3.3
                  EEEEESTTSSHHHHHHHHHT CS
      FeoB_N    3 valvGnpnvGkttlfnaltg 22  
                  v lvG+  +Gkt +  a+++
  EEA22601.1 1354 VLLVGETGCGKTQICQAVAE 1373
                  689***********998875 PP

  == domain 4  score: 1.5 bits;  conditional E-value: 0.68
                  EEEEESTTSSHHHHHHHHHT CS
      FeoB_N    3 valvGnpnvGkttlfnaltg 22  
                  + l G p vGkttl+ +l+ 
  EEA22601.1 1738 ILLEGSPGVGKTTLVASLAR 1757
                  6789***********99976 PP

  == domain 5  score: -2.1 bits;  conditional E-value: 8.7
                  EEEESTTSSHHHHHHHHHT CS
      FeoB_N    4 alvGnpnvGkttlfnaltg 22  
                  +lvG   +Gktt + +l+ 
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLAS 2065
                  589**********999875 PP

>> Septin  Septin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.1     0.092        26       7      36 ..     629     658 ..     624     669 .. 0.75
   2 ?    0.1   0.0       1.4   3.9e+02       7      26 ..    1738    1757 ..    1734    1772 .. 0.87
   3 ?    3.3   0.0      0.14        41       8      28 ..    2047    2067 ..    2044    2097 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.092
                 EEEEEBTTSSCCCCCCTTSSSS-------- CS
      Septin   7 lmvvGesglGkttlintlfetdlieeekle 36 
                 +++vGe g+Gkt++i+ l + + ++ + ++
  EEA22601.1 629 VLLVGETGIGKTAVIQQLANLTCQKLTVVN 658
                 799**************9987776665444 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 1.4
                  EEEEEBTTSSCCCCCCTTSS CS
      Septin    7 lmvvGesglGkttlintlfe 26  
                  +++ G+ g+Gkttl+ +l +
  EEA22601.1 1738 ILLEGSPGVGKTTLVASLAR 1757
                  68889************975 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.14
                  EEEEBTTSSCCCCCCTTSSSS CS
      Septin    8 mvvGesglGkttlintlfetd 28  
                  ++vG sg Gktt i+tl + +
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLASIQ 2067
                  689*************98755 PP

>> tRNA_lig_kinase  tRNA ligase kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.0     0.023       6.6       6      34 ..    1358    1386 ..    1354    1398 .. 0.84
   2 ?    3.3   0.0      0.27        77       8      24 ..    2052    2068 ..    2047    2089 .. 0.87

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.023
                       --TTSSHHHHHHHHHHH-TTSEEEEGGGS CS
  tRNA_lig_kinase    6 atiGCGkttvaltlenlfgeWghvqnDni 34  
                          GCGkt + +++ +++g+  +++n  +
       EEA22601.1 1358 GETGCGKTQICQAVAEIYGKEMYIVNAHV 1386
                       567****************9888888766 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.27
                       TTSSHHHHHHHHHHH-T CS
  tRNA_lig_kinase    8 iGCGkttvaltlenlfg 24  
                        GCGktt+ +tl ++ g
       EEA22601.1 2052 SGCGKTTTIRTLASIQG 2068
                       59**********99876 PP

>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0       1.2   3.4e+02       4      22 ..     294     312 ..     292     333 .. 0.76
   2 ?   -0.3   0.1       2.5     7e+02       4      23 ..     630     649 ..     628     666 .. 0.77
   3 ?   -1.0   0.0       4.1   1.2e+03       4      23 ..    1065    1084 ..    1063    1120 .. 0.83
   4 ?    4.4   0.1     0.089        25       4      21 ..    1739    1756 ..    1737    1766 .. 0.86
   5 ?    3.0   0.1      0.24        68       4      21 ..    2047    2064 ..    2045    2077 .. 0.81

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 1.2
                 EEEESTTCCHHHHHHHHHC CS
        cobW   4 vltGflGsGKTtLlnhlle 22 
                 +l+G + sGKT+L+n + +
  EEA22601.1 294 LLVGLPNSGKTSLVNDIAK 312
                 689999*********9973 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 2.5
                 EEEESTTCCHHHHHHHHHCT CS
        cobW   4 vltGflGsGKTtLlnhllen 23 
                 +l+G  G GKT+++++l + 
  EEA22601.1 630 LLVGETGIGKTAVIQQLANL 649
                 6899***********99843 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 4.1
                  EEEESTTCCHHHHHHHHHCT CS
        cobW    4 vltGflGsGKTtLlnhllen 23  
                  +l G+  sGKT++++ l + 
  EEA22601.1 1065 LLQGPTSSGKTSMVEYLAKV 1084
                  6899999*******998754 PP

  == domain 4  score: 4.4 bits;  conditional E-value: 0.089
                  EEEESTTCCHHHHHHHHH CS
        cobW    4 vltGflGsGKTtLlnhll 21  
                  +l G++G GKTtL+ +l 
  EEA22601.1 1739 LLEGSPGVGKTTLVASLA 1756
                  689***********9986 PP

  == domain 5  score: 3.0 bits;  conditional E-value: 0.24
                  EEEESTTCCHHHHHHHHH CS
        cobW    4 vltGflGsGKTtLlnhll 21  
                  +l+G+ G GKTt +++l 
  EEA22601.1 2047 ILVGPSGCGKTTTIRTLA 2064
                  89*************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (4898 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1325  (0.0739026); expected 358.6 (0.02)
Passed bias filter:                      642  (0.0358079); expected 358.6 (0.02)
Passed Vit filter:                       162  (0.00903564); expected 17.9 (0.001)
Passed Fwd filter:                        92  (0.00513135); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              63  [number of targets reported over threshold]
# CPU time: 3.13u 0.39s 00:00:03.52 Elapsed: 00:00:00.73
# Mc/sec: 20188.88
//
Query:       EEA22602.1  [L=424]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-35  123.6  18.2    1.9e-35  123.6  18.2    3.0  2  PRCC      Mitotic checkpoint regulator, MAD2B-interacting


Domain annotation for each model (and alignments):
>> PRCC  Mitotic checkpoint regulator, MAD2B-interacting
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   4.5      0.24   4.3e+03      24      53 ..      15      41 ..       4      85 .. 0.44
   2 !  123.6  18.2   1.1e-39   1.9e-35       1     214 []     255     424 .]     191     424 .] 0.69

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.24
        PRCC 24 syeplvssapeaeeseeedppetepepasq 53
                +++p+v+++ +++++++ +   t+p++++q
  EEA22602.1 15 EEQPQVTQPTTKPQPPAPE---TKPSQSDQ 41
                2233333333332222211...11111111 PP

  == domain 2  score: 123.6 bits;  conditional E-value: 1.1e-39
        PRCC   1 dfFSlesasassssaaaksaptisyeplvssapeaeeseeedppetepepasqpeaenadleakkaaksseamvpepteqdpvkensknypgyyllpsg 99 
                 ++FS+     ss+++aa++ +t+ ye +v++++ a+e+++              e+  ++le  +++                 ++s++ p+++++   
  EEA22602.1 255 SLFSF-----SSEEKAAPTPSTSRYESIVYNPEFANEPST-------------IEEDISTLEQHNQP-----------------STSYPTPSTQQQ--- 315
                 45555.....222222222233333333333332222222.............11111222211111.................112222322222... PP

        PRCC 100 sqqpqe....dasdlnlddealrqLlGrrggnrkreeikeakiieinedeelkaneqwlakalteekaekkgnpvrgqakrKHQltyLahqAkeneeeL 194
                      +    +a+dlnl+ +++rqLlGr+ +     ++ +++i+++n+d+e+++n++ l++  +ee a++++npvr++a++KH+l++L+++A +++++L
  EEA22602.1 316 -----StldaIANDLNLSRAQRRQLLGRNTA-----AQTNSRILTFNTDAEYASNQEILSRTTEEELAAQQHNPVRAIAPGKHSLRQLVQAANSQKDAL 404
                 .....23455*****************9944.....677788********************************************************* PP

        PRCC 195 eeswAenrrnRkqaqaKYGF 214
                 e+s+A++rrn+k+a+++YG+
  EEA22602.1 405 EDSFAAGRRNKKEAGSRYGW 424
                 ******************** PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (424 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       941  (0.0524848); expected 358.6 (0.02)
Passed bias filter:                      410  (0.022868); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2903.16
//
Query:       EEA22603.1  [L=348]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (348 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1977  (0.110268); expected 358.6 (0.02)
Passed bias filter:                      552  (0.0307881); expected 358.6 (0.02)
Passed Vit filter:                        90  (0.0050198); expected 17.9 (0.001)
Passed Fwd filter:                        28  (0.00156172); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.77u 0.32s 00:00:01.09 Elapsed: 00:00:00.51
# Mc/sec: 2034.22
//
Query:       EEA22604.1  [L=325]
Description: lectin family integral membrane protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.5e-67  224.7   0.0    1.3e-66  224.3   0.0    1.1  1  Lectin_leg-like  Legume-like lectin family
    7.2e-09   35.9   0.1    9.8e-09   35.5   0.1    1.1  1  Bact_lectin      Bacterial lectin
    1.6e-05   24.6   0.0      0.011   15.2   0.0    2.1  2  Lectin_legB      Legume lectin domain


Domain annotation for each model (and alignments):
>> Lectin_leg-like  Legume-like lectin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  224.3   0.0   2.2e-70   1.3e-66       5     227 ..      37     259 ..      34     262 .. 0.93

  Alignments for each domain:
  == domain 1  score: 224.3 bits;  conditional E-value: 2.2e-70
                      GGGECCCTSCTCTTSSBTTEEEEET-EEE.SSEEEEE-SSTTEEEEEEESS-BEESSEEEEEEEEEESS--SS-S-EEEEEEESSSSSCCSBTT CS
  Lectin_leg-like   5 rehslkkPylgqgskalpnWeyggsaild.snqirltsdeqskkGslwtkspvaleswevevsFrvtgseselegdglaiwytsergkegpvFg 97 
                      r hsl  Pyl + +++  +W++gg++++  ++++rlts+ qs++G+++++ p++  +we+e++F+++gs ++l+gdg+a+w+t+ r+++gpvFg
       EEA22604.1  37 RTHSLVPPYLDSDMHSR-WWDFGGDTVIRtDQYVRLTSERQSQQGWIFSRVPLTATNWEIEFEFKIHGS-GHLHGDGFALWLTKGRATPGPVFG 128
                      78*********997776.*******9997699*************************************.88********************** PP

                      B-SS-EEEEEEEE-S-TSCTTTSS-SSEEEEEEEESSC---GGGTTTTTESEEEE-.--BTESSEEEEEEEEETTEEEEEEETSCCSCCCTTEE CS
  Lectin_leg-like  98 skdkfdGlailldtydndngpdkknkptisamlndgsleydhekdgkaqelasCta.dfrnkdvetlikikYdknaltvlidsgllenkndykl 190
                      s+d+f+Gl+i++dty+n++++  + +p+++am++dg+++yd+e+dgk++ela+C+a + r+  ++t+++++Y ++ ++++ d  + +  +++  
       EEA22604.1 129 SADRFEGLGIFFDTYKNNRPG--TSFPYVMAMMGDGQTSYDQEHDGKDNELAGCSArGIRDAAIPTKARLTYFQD-RSLTLDLQY-KSDSSWTE 218
                      *******************88..8*******************************989**************975.567777666.999***** PP

                      EEEE....SSEE--SSBEEEEEEEESSSGGEEEEEEEEEEE CS
  Lectin_leg-like 191 Cfqv....kevelPtgyyfgvsaatgdlsdnhdvlsllllq 227
                      Cf++    +++ +P+  y+g+s +tg++ d hd++s+ + +
       EEA22604.1 219 CFSLsaadTNIAIPSVAYLGFSGETGEVTDVHDIISVVTHN 259
                      **984444599*************************98876 PP

>> Bact_lectin  Bacterial lectin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.5   0.1   1.6e-12   9.8e-09       9     190 ..      54     251 ..      46     254 .. 0.79

  Alignments for each domain:
  == domain 1  score: 35.5 bits;  conditional E-value: 1.6e-12
                  HEEEEET-E...E.EEEEE-SSTT-EEEEEESSEEETTS-EEEEEEEE--S...B.--EEEEEEEST----SGGGTTTTTSTT-EEEEEE-S--.... CS
  Bact_lectin   9 yfnlngtatkksk.ivtltedkknqaGavtlknkiDlskdFtlkgsvnlgqsnaggaDGigFalqpgqlGssGgglGigglpnafgfklDtyyN...k 102
                   +++ g++   ++ +v+lt + ++q+G + ++ ++    ++++++++ + +s +  +DG+++ l +    ++G  +G +    ++g+ +Dty N   +
   EEA22604.1  54 WWDFGGDTVIRTDqYVRLTSERQSQQGWIFSRVPLTA-TNWEIEFEFKIHGSGHLHGDGFALWLTK-GRATPGPVFGSADRFEGLGIFFDTYKNnrpG 149
                  566667555444469**************99999988.79**********999999*********9.33468**********************9987 PP

                  .SS-EEEEEEE............-TT-..............-SSS--EEEEEEE..-TTTEEEET.....HHHT-.............SEEEEEEEEE CS
  Bact_lectin 103 agkpygafvktdangsletvkssssks..............ledgkwhpitisYdastkttvtyd.....dgsstvsidltkkvtkgktyvafgiaas 181
                   + py++ +  d++ s ++  +++++               +      + +++Y ++ + t++++     ++++  s     +++      ++g++++
   EEA22604.1 150 TSFPYVMAMMGDGQTSYDQEHDGKDNElagcsargirdaaiP-----TKARLTYFQDRSLTLDLQyksdsSWTECFSLSAADTNIAIPSVAYLGFSGE 242
                  788899999998887777766664444799999*98776651.....5556666333333333334466678999999999999999*********** PP

                  -SSSB--EE CS
  Bact_lectin 182 tGgatnlqq 190
                  tG+ t  + 
   EEA22604.1 243 TGEVTDVHD 251
                  **9988775 PP

>> Lectin_legB  Legume lectin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   1.9e-06     0.011      19     109 ..      58     143 ..      51     177 .. 0.80
   2 !    7.5   0.0   0.00045       2.7     170     230 ..     198     254 ..     182     271 .. 0.70

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 1.9e-06
  Lectin_legB  19 egdAsvsasgllqLtnktsnssvGralYkkplkLwdkssgnvasFstsFvfaIssskssssgdGlAFflaps.....pslpaasagqyLGLfnstt 109
                   gd+ +  ++ ++Lt++ ++ + G+++  + ++L       +++++ +F f+I   +   +gdG+A  l++      p + +a+  + LG+f +t 
   EEA22604.1  58 GGDTVIRTDQYVRLTSERQS-QQGWIF--SRVPLT------ATNWEIEFEFKIH-GSGHLHGDGFALWLTKGratpgPVFGSADRFEGLGIFFDTY 143
                  57888888999***999877.889997..556666......468*********4.455899*********99877666788888999999994443 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.00045
  Lectin_legB 170 YdsaskrlsVtlaplkeeskpkkpllsykvdLskvlpeekvyvGFSastgsvsveahyils 230
                  Y +  + l+  l+ +k++s+ ++       d +  +p + +y GFS+ tg+v+   h i+s
   EEA22604.1 198 YFQ-DRSLTLDLQ-YKSDSSWTECFSLSAADTNIAIP-SVAYLGFSGETGEVT-DVHDIIS 254
                  554.456666666.55543223322223567777889.57***********77.9999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (325 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       570  (0.0317921); expected 358.6 (0.02)
Passed bias filter:                      467  (0.0260472); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 2184.56
//
Query:       EEA22605.1  [L=112]
Description: mitochondrial intermembrane space translocase subunit Tim13, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.1e-21   73.8   0.1    8.8e-21   73.3   0.1    1.2  1  zf-Tim10_DDP  Tim10/DDP family zinc finger


Domain annotation for each model (and alignments):
>> zf-Tim10_DDP  Tim10/DDP family zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.3   0.1   4.9e-25   8.8e-21       1      62 [.      26      86 ..      26      88 .. 0.96

  Alignments for each domain:
  == domain 1  score: 73.3 bits;  conditional E-value: 4.9e-25
  zf-Tim10_DDP  1 qqleqeqqvanaqelvnkltekCfkkCigkypgssLdsseesCldnCvdryldvsnlvskrl 62
                  q +++e++van + l+nk++e+Cf++Ci++ pgs+L+ +e++Cl++C+d+y+  +n+ s+++
    EEA22605.1 26 QSVQAEAAVANTRILINKINENCFDRCIPT-PGSTLSAGESTCLSSCMDKYINLWNVTSRAY 86
                  5799************************88.****************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (112 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       602  (0.0335769); expected 358.6 (0.02)
Passed bias filter:                      391  (0.0218082); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.29s 00:00:00.73 Elapsed: 00:00:00.46
# Mc/sec: 729.38
//
Query:       EEA22606.1  [L=481]
Description: cAMP-dependent protein kinase catalytic subunit PkaC1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.6e-73  245.3   0.0    9.4e-73  244.8   0.0    1.2  1  Pkinase      Protein kinase domain
      3e-37  128.3   0.0    4.5e-37  127.7   0.0    1.2  1  Pkinase_Tyr  Protein tyrosine kinase
    6.3e-06   25.7   0.1      1e-05   25.0   0.1    1.4  1  Kinase-like  Kinase-like
  ------ inclusion threshold ------
      0.072   13.2   7.2       0.13   12.4   7.2    1.3  1  KCT2         Keratinocyte-associated gene product
        5.8    4.9  12.3        7.4    4.6  12.3    1.1  1  Hid1         High-temperature-induced dauer-formation protein


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  244.8   0.0   2.6e-76   9.4e-73       2     264 .]     171     425 ..     170     425 .. 0.94

  Alignments for each domain:
  == domain 1  score: 244.8 bits;  conditional E-value: 2.6e-76
                 EEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHH.HHHHHHHHHHHHHSCTTB--EEEEEEESSEEEEEEE--TTEBHHHHHHHHSS--HHH CS
     Pkinase   2 ekleklGeGsfGkVykaveketgkivAvKkikkekakkkke.kkvlrEikilkklkhpnivrlyevfeekdelylvleyveggeladllerkgslseee 99 
                 + +++lG+GsfG+V  + ++++++ +A+K++kk +  k+k+ +++  E ++l+++khp++++l+++f+++++ly+v+++veggel++ll++++ +++  
  EEA22606.1 171 SLQRTLGTGSFGRVHLVQSRHNHRFYAIKVLKKAQVVKMKQvEHTNDERRMLQRVKHPFLITLWGTFQDSKNLYMVMDFVEGGELFSLLRKSQRFPNPV 269
                 56899***********************************99********************************************************* PP

                 HHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCSBCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHHHHHSS-STT CS
     Pkinase 100 akkiakqilegleylHskgiiHrDlKpeNiLidekgelKitDFGlakelessskltsfvgtseYlAPEvlkeneyskkvDvWslGvilyelltgkppfs 198
                 ak++a+++  +leylH+++ii+rDlKpeN+L+d++g+lKitDFG+ake+   +   + +gt++YlAPEv+++++y k+vD+WslG++++e+l+g +pf+
  EEA22606.1 270 AKFYAAEVTLALEYLHAQHIIYRDLKPENLLLDRHGHLKITDFGFAKEVPDIT--WTLCGTPDYLAPEVVSSKGYNKSVDWWSLGILIFEMLCGFTPFW 366
                 *************************************************9965..******************************************** PP

                 TSSHHHHHHHHHHTHHHHHHHCTSHH...HHHTTS-HHHHHHHHHHT-SSGCCSTT.....HHHHHTSGGG CS
     Pkinase 199 gekgkekvekeldqlekilkilgetkeklpeaseiseeakdllkkllkkdpkkRlt.....aeellqhpyl 264
                 ++ +     k++++      il   + k++ +  + ++a dll++l++ d +kRl+      e++++hp++
  EEA22606.1 367 DSGSPV---KIYEN------IL---RGKIKYPPYMHPDAVDLLSQLITPDLTKRLGnlhggPEDVKNHPWF 425
                 443333...33333......44...34789999***********************99999*********8 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.7   0.0   1.2e-40   4.5e-37       2     249 ..     171     408 ..     170     410 .. 0.88

  Alignments for each domain:
  == domain 1  score: 127.7 bits;  conditional E-value: 1.2e-40
                  EEEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTT..SSHHHHHHHHHHHHHHHTS-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHTCT CS
  Pkinase_Tyr   2 elgkklGeGafGkVvegtlkgekekkevkVavKtlkee..ateeekeelleeakimkklkhpnivkllgvctkeepllivteyvkgGdLlkfLrkkek 97 
                  +l+++lG G+fG+V+  + +    +++   a+K+lk+    + ++ e+  +e ++++++khp ++ l g   ++++l++v+++v+gG+L + Lrk+  
   EEA22606.1 171 SLQRTLGTGSFGRVHLVQSR----HNHRFYAIKVLKKAqvVKMKQVEHTNDERRMLQRVKHPFLITLWGTFQDSKNLYMVMDFVEGGELFSLLRKS-- 262
                  6899***********99999....666777888886541145555778888********************************************8.. PP

                  TTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEETTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSEEEHHHHHHHHHHHH CS
  Pkinase_Tyr  98 ekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsenkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekkftsksDvWsfGvll 195
                  +++       +a++v  ++eyL++++++ rdl   N Ll+++ + ki+DfG a+++        + +      ++apE++++k ++++ D Ws G+l+
   EEA22606.1 263 QRFPNPVAKFYAAEVTLALEYLHAQHIIYRDLKPENLLLDRHGHLKITDFGFAKEV-----PDITWTLCGTPDYLAPEVVSSKGYNKSVDWWSLGILI 355
                  778888888899********************************************.....223344455679************************* PP

                  HHHHTTSSGTTTTS.HHHHHHHHHHTTEES-BBTTSBHHHHHHHHHHT-SSGGGS CS
  Pkinase_Tyr 196 wEiftlgespypgl.kneevleklkegkrlekpekcpeelyelmkkcweedpeeR 249
                  +E+++ g +p+++  ++ +++e++ +gk ++ p +++++  +l+++  + d ++R
   EEA22606.1 356 FEMLC-GFTPFWDSgSPVKIYENILRGK-IKYPPYMHPDAVDLLSQLITPDLTKR 408
                  ****9.*******999********9886.67788888899999999888887777 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.0   0.1   2.8e-09     1e-05     125     251 ..     253     366 ..     139     401 .. 0.82

  Alignments for each domain:
  == domain 1  score: 25.0 bits;  conditional E-value: 2.8e-09
  Kinase-like 125 eilnkvlqkrsethkkletiarlllTlqlirlaanLqakglvhgkftvdnllldekgglmlggftaLvragtkvvl.sevekgfaPpEllgsrggytr 221
                  + l+++l k + + ++ ++   + +Tl       +L+a+ ++  +++++nllld++g l++++f+    + +       ++  +  pE+++s+g y++
   EEA22606.1 253 GELFSLLRKSQRFPNPVAKFYAAEVTL----ALEYLHAQHIIYRDLKPENLLLDRHGHLKITDFGFAKEVPDITWTlCGTPD-YLAPEVVSSKG-YNK 344
                  567777888887766666655555555....4489*****************************988888776664255555.55679999955.454 PP

  Kinase-like 222 knktkmthkldaWqlGlviyriwclklPlt 251
                          ++d W lG+ i+ + c   P+ 
   EEA22606.1 345 --------SVDWWSLGILIFEMLCGFTPFW 366
                  ........89**************999984 PP

>> KCT2  Keratinocyte-associated gene product
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   7.2   3.5e-05      0.13       9     109 ..      13     115 ..       6     129 .. 0.71

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 3.5e-05
        KCT2   9 tlkaptaekssaasaasrvsaassvseeeadasedtsleeedlltlnsspsvikdtldnGdyGepdydlttssr.....deesdeiseenreykel..e 100
                 t ++ ++e s++++aas  ++++s+s++ ad+ e+++ e +d   +ns+ s+  ++ +n   G++d ++t +s          +++ + + + + l   
  EEA22606.1  13 THSTGSKELSASSTAASAEAPTTSASDKPADETEQSK-ESND-SNINSAGSTGAEASNNTKSGSNDIQMTLNSStnqqiA---QDANNSSSHHHYLpnI 106
                 5566777899999*****************9998776.4444.478************************9987433222...3333333332222002 PP

        KCT2 101 esvksvkvp 109
                  s+ks+  p
  EEA22606.1 107 GSIKSIINP 115
                 355555555 PP

>> Hid1  High-temperature-induced dauer-formation protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6  12.3    0.0021       7.4     563     708 ..       9     162 ..       4     245 .. 0.62

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.0021
        Hid1 563 rkrkvfealrnltlesaseeiersne..sarldsideeeeenssessrieesrsesrspslsevpelksslaitddeskaereksatessssqavs... 656
                 +k+   +++ + +l+++s + + ++   sa+ + +de e++++s++s+i+++ s   ++s ++ ++  + +++t + s +++  ++ ++sss+  +   
  EEA22606.1   9 KKK-KTHSTGSKELSASSTAASAEAPttSASDKPADETEQSKESNDSNINSAGSTGAEASNNT-KSGSNDIQMTLNSSTNQQIAQDANNSSSHH-Hylp 104
                 444.34555566666666555555554455566666666666666777777666655553333.333333444433333333333333333332.1355 PP

        Hid1 657 ......qlremsekarakesaesteesrqesatskkspsgmsqsaeekftptsewles 708
                          +++++++++  +++++ ++++++++++s ++ +q+++++++++++   +
  EEA22606.1 105 nigsikSIINPTHHQHGNDVQGQDHAEHTNNNNNNSSTQNYVQTSQGQLPKSQSRQTK 162
                 6777776778889999999999999999999999999999999999999998875555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (481 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1416  (0.0789782); expected 358.6 (0.02)
Passed bias filter:                      494  (0.0275531); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.65u 0.33s 00:00:00.98 Elapsed: 00:00:00.47
# Mc/sec: 3088.09
//
Query:       EEA22607.1  [L=836]
Description: stress activated MAP kinase interacting protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-36  125.6   0.0      3e-36  124.6   0.0    1.6  1  CRIM      SAPK-interacting protein 1 (Sin1), middle CRIM doma
    5.3e-26   91.0   0.1      9e-26   90.3   0.1    1.4  1  SIN1_PH   SAPK-interacting protein 1 (Sin1), Pleckstrin-homol
  ------ inclusion threshold ------
      0.033   14.4   0.0       0.14   12.4   0.0    2.0  2  TUG-UBL1  TUG ubiquitin-like domain


Domain annotation for each model (and alignments):
>> CRIM  SAPK-interacting protein 1 (Sin1), middle CRIM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  124.6   0.0   5.1e-40     3e-36       2     139 ..     361     518 ..     360     520 .. 0.97

  Alignments for each domain:
  == domain 1  score: 124.6 bits;  conditional E-value: 5.1e-40
                 --SSS---SSSS-SSSCCCCCGCCTTTT.-T-EEECCE-TT-SSTTS.---CCC-.........SSSCTCCCCCCCCCCCHCHT-SS-SS...SCGGCS CS
        CRIM   2 SlLsalLeakkeksenpleeyaalsgkgessslklkiyvpfskkpsvkplevkvr.........kdatvaevIGlaLykyveekrepeldeeleeekln 91 
                 SlLs+ L+akk  ++np+e++  l + +++++l++kiy+pfs++p+ +p+++++           ++tv e+IGlaL++y +e+ +p++d     +kln
  EEA22607.1 361 SLLSKELNAKKAIPTNPVERFGPLWAADSNTALNIKIYAPFSEDPE-TPYNMPIFrdsrdqgrtGPVTVTEAIGLALWRYLKEGLKPAID----PNKLN 454
                 9************************99988****************.6******99******988*************************....799** PP

                 TTCCEECCE-CT--EECCCCCC-TTSCCHHH-.................BSEEEEEE-SCHHHCC CS
        CRIM  92 vnrwtLriveeDgevdedFPaldrtrpiskfs.................fdelaLveaseeevee 139
                 vnrwtLr+v eDgevd dFPal r+ p+++f+                 +de+aLvea+++e+ee
  EEA22607.1 455 VNRWTLRMV-EDGEVDFDFPALGRHLPLADFTsnnnraagmrgrsrgkqYDEFALVEATDAEFEE 518
                 *********.6****************************************************97 PP

>> SIN1_PH  SAPK-interacting protein 1 (Sin1), Pleckstrin-homology
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   90.3   0.1   1.5e-29     9e-26       2     109 ..     725     831 ..     724     832 .. 0.94

  Alignments for each domain:
  == domain 1  score: 90.3 bits;  conditional E-value: 1.5e-29
     SIN1_PH   2 lyksyrvyikqkm..laksevtLaIdgekieidpvknkkkatkfwaksqKtvsyhidsvvhckiserksskalfrivvkk..sssefKrydfeadsake 96 
                 +y++y vy+kq m  +a+++++L++d+++++++p ++ k +   +  ++Kt+s++++++++ k+s+r+++  +f++vv +  +++e+Krydfea++++e
  EEA22607.1 725 YYRRYYVYRKQSMsfTASNQRVLVLDNDYLHVMPGETAKGV---FDATGKTRSINFNDIIGTKVSRRHPK--SFQVVVLRgtDAHEQKRYDFEARNEAE 818
                 69***********99999*******************7754...5667**********************..*******99999*************** PP

     SIN1_PH  97 AeeIvnkinkile 109
                 A+eIv +i+k +e
  EEA22607.1 819 AAEIVGEIKKNME 831
                 **********998 PP

>> TUG-UBL1  TUG ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0       1.1   6.7e+03      17      41 ..     439     463 ..     438     473 .. 0.73
   2 ?   12.4   0.0   2.3e-05      0.14       5      41 ..     608     644 ..     604     658 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 1.1
    TUG-UBL1  17 tlndvLeeackkfklddsasytLk.h 41 
                 +l++ L+ a    kl + +++tL+  
  EEA22607.1 439 YLKEGLKPAIDPNKL-NVNRWTLRmV 463
                 677778888888899.889***9854 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 2.3e-05
    TUG-UBL1   5 frrfkvkvtpnttlndvLeeackkfklddsasytLk.h 41 
                  ++++v ++  +++ ++L+ +ck+ +l d+ +y Lk  
  EEA22607.1 608 TQTTTVNTATDSYIAEILDSVCKRWGL-DKGNYLLKiP 644
                 58999**********************.777****953 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (836 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       538  (0.0300073); expected 358.6 (0.02)
Passed bias filter:                      435  (0.0242624); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.68u 0.26s 00:00:00.94 Elapsed: 00:00:00.47
# Mc/sec: 5359.75
//
Query:       EEA22608.1  [L=1031]
Description: DNA replication factor C subunit Rfc1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.8e-58  196.5   0.0    9.9e-58  194.7   0.0    1.9  2  RFC1             Replication factor RFC1 C terminal domain
    2.8e-15   56.4   0.0      8e-15   55.0   0.0    1.9  1  BRCT             BRCA1 C Terminus (BRCT) domain
      1e-09   38.9   1.2    1.7e-09   38.2   0.0    1.9  2  AAA              ATPase family associated with various cellul
    1.5e-06   28.3   0.0    4.4e-06   26.8   0.0    1.8  1  Rad17            Rad17 P-loop domain
    2.7e-05   24.5   0.0    6.5e-05   23.2   0.0    1.6  1  AAA_22           AAA domain
      7e-05   22.6   0.0      0.007   16.1   0.0    2.4  2  RuvB_N           Holliday junction DNA helicase RuvB P-loop d
    0.00043   20.7   0.0     0.0062   16.9   0.1    2.5  2  AAA_16           AAA ATPase domain
     0.0009   19.4   0.0     0.0026   17.9   0.0    1.8  1  AAA_33           AAA domain
     0.0063   16.8   1.1       0.19   12.0   0.1    2.5  2  AAA_28           AAA domain
       0.01   15.6   0.0       0.01   15.6   0.0    1.7  1  AAA_30           AAA domain
  ------ inclusion threshold ------
      0.017   15.7   0.0      0.079   13.5   0.0    2.3  1  AAA_18           AAA domain
      0.021   14.6   0.1      0.051   13.3   0.1    1.6  1  Sigma54_activat  Sigma-54 interaction domain
      0.027   14.5   0.0      0.089   12.8   0.0    1.9  2  AAA_5            AAA domain (dynein-related subfamily)
      0.044   13.8   0.0       0.11   12.5   0.0    1.6  1  AAA_14           AAA domain
      0.068   13.1   0.0       0.99    9.3   0.0    2.3  2  NACHT            NACHT domain
       0.12   12.3   0.0       0.32   11.0   0.0    1.8  1  PTCB-BRCT        twin BRCT domain
       0.13   12.1   0.1       0.36   10.7   0.1    1.7  2  NTPase_1         NTPase
        2.1    8.1  11.0        1.2    8.9   0.0    3.5  3  AAA_11           AAA domain
          6    7.1  11.2      0.048   13.5   1.8    2.9  1  AT_hook          AT hook motif


Domain annotation for each model (and alignments):
>> RFC1  Replication factor RFC1 C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       4.4   4.2e+03      94     122 ..     653     681 ..     646     695 .. 0.77
   2 !  194.7   0.0   1.1e-60   9.9e-58       1     157 []     774     927 ..     774     927 .. 0.96

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 4.4
                 S---------HHHHHHTTT--SHHHHHHH CS
        RFC1  94 kpLkeegkdgveevielmdeysLtkedvd 122
                 + L    ++ + + i+++++ +L ++ +d
  EEA22608.1 653 DSLIAGTNADIRQLINMLSTVKLDQKTLD 681
                 556665556699********999998754 PP

  == domain 2  score: 194.7 bits;  conditional E-value: 1.1e-60
                 HHHHHHHHHHHTT.SS-GGGHHHHHHHHTHHHHHTT-EE-SS-----SHHHHHHHHHHHHHHHHHHHTTTTT------HHHHHTTTHHHHHHHHS---- CS
        RFC1   1 isdgDlvdkkirs.eqnWsLlpthavlssvlPaslvrgslegrisFpswLGknSktnKnkRllqelqshlrlktsaskselrldylpllkkklvkpLke 98 
                 isdgDlvd++i++ +q+WsL+pthav+s v+Pas++ g++ +r+sF+swLG+nSk +K +R+ +e+q h+rl+ s++++e+r++ylp l++k+v+pL+ 
  EEA22608.1 774 ISDGDLVDRMIHGsQQQWSLMPTHAVFSFVRPASFIFGNMMERTSFTSWLGNNSKYGKLNRYTKEIQGHMRLRASGDRDEIRQQYLPALWDKMVRPLMV 872
                 9************************************************************************************************** PP

                 -----HHHHHHTTT--SHHHHHHHHHH-X...XXXXXXXXXXXXXXXXXXXXXXXXXXX CS
        RFC1  99 egkdgveevielmdeysLtkedvdslvelslvkgekkkedplkkidtkvKaaftrkynk 157
                 +gkd+ve+vi+lmd+y++t+ed+ds+vel l+   +  ++ + +i+t++K+aftr yn+
  EEA22608.1 873 DGKDAVEDVIDLMDSYFITREDFDSIVELGLG---PM-SESVVDIHTQTKSAFTRIYNQ 927
                 *****************************888...33.345679*************96 PP

>> BRCT  BRCA1 C Terminus (BRCT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.0   0.0   8.5e-18     8e-15       3      79 .]     301     376 ..     299     376 .. 0.98

  Alignments for each domain:
  == domain 1  score: 55.0 bits;  conditional E-value: 8.5e-18
                 TTTTTTEEEEEEESTSSHHHHHHHHHHHHTTCEEESSCSTTSSEEEESSSHSHHHHHHHHHHTTSEEEETHHHHHHH CS
        BRCT   3 ellfhgckfvitgvldnftrdeleelikehGGkvttevskktthlvvgepesrslkylealklnipivheewlldci 79 
                 e+++ g++fv+tgvld+  r+e ++l+k +GGkvt++ s+kt+++v g++ ++ +k+ + ++ ni+++ ee l+++i
  EEA22608.1 301 ENCLAGLSFVFTGVLDSLGREEGQSLVKRYGGKVTGAPSSKTSYVVLGSD-AGPSKLRKIKEMNIKTIGEEGLFELI 376
                 799***********************************************.***********************987 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.3       8.4     8e+03      77      99 ..     394     416 ..     387     426 .. 0.71
   2 !   38.2   0.0   1.8e-12   1.7e-09       1      74 [.     498     582 ..     498     611 .. 0.76

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 8.4
                 CCCHHHHHHHHHHHHHHHHTTTS CS
         AAA  77 seseeeervvnqLlteldgvkkk 99 
                 +++e ee+ + ++ +e+++++k+
  EEA22608.1 394 AKKEAEEKKIRAMAEEMEQEEKQ 416
                 56667777777777777777765 PP

  == domain 2  score: 38.2 bits;  conditional E-value: 1.8e-12
                 EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSS........STTHHHHHHHHHHHHHHHTS....TSEEEEEETGGGHHHHH CS
         AAA   1 vllyGppGtGKTllakavakelgvefleisgsellsk........yvgesekkirelfkeakeka....kpsilfiDEidalaksr 74 
                 v+++GppG+GKT++a+ vak  g +++e+++s+ +sk         v     +++++f++  ++     k  +l++DE+d +   +
  EEA22608.1 498 VMIHGPPGIGKTTAAHLVAKLEGYDVVETNASDTRSKklvegsllGV-LDTTSLQGYFSSEGKNVesqkKNLVLIMDEVDGMSAGD 582
                 689********************************888999997522.234456666655322224664459********996554 PP

>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.0   4.6e-09   4.4e-06       7      95 ..     445     544 ..     441     574 .. 0.84

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 4.6e-09
       Rad17   7 elWfekykPekaeelavhkkkieevkewlkadvLesrkkr............iLLisGPsGCgkstvvkvLskelgiklrewlnpvslkepdnqksdfk 93 
                  lW  ky P  ++ +   k ++e++++wl+   L+ ++k              ++i GP+G gk+t+ + ++k  g+++ e  n+   ++ +  +  ++
  EEA22608.1 445 RLWTTKYAPSSLNMICGNKGQVEKLQTWLRNWRLNAKRKFkmagkdgsglyrSVMIHGPPGIGKTTAAHLVAKLEGYDVVET-NASDTRSKKLVEGSLL 542
                 68********************************988665688999999888899***********************9985.5555466655555555 PP

       Rad17  94 gl 95 
                 g+
  EEA22608.1 543 GV 544
                 55 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.2   0.0   6.9e-08   6.5e-05       7     131 ..     497     606 ..     494     612 .. 0.84

  Alignments for each domain:
  == domain 1  score: 23.2 bits;  conditional E-value: 6.9e-08
      AAA_22   7 ilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdllrellralglelkaerlsseellealeqalraravielliiDEaqhlrs 105
                 +++++G++G+GKTt +  +++           + +vv+ +++   s k +   ll  l+      + s++ +++   ++++++++  +li DE++ + s
  EEA22608.1 497 SVMIHGPPGIGKTTAAHLVAKLE---------GYDVVETNASDTRSKKLVEGSLLGVLD------TTSLQGYFSSEGKNVESQKKNLVLIMDEVDGM-S 579
                 789*****************998.........***********9999998889988888......4799999988888888888889**********.5 PP

      AAA_22 106 ...eealeeLrsllnlsrkgvqliLvGtp 131
                       +  L   ++  +++++liL+  +
  EEA22608.1 580 agdRGGVGALAAAAK--KTNIPLILICNE 606
                 455777777766688..999999998765 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0     0.045        42       7      81 ..     165     245 ..     161     259 .. 0.74
   2 !   16.1   0.0   7.4e-06     0.007      35      66 ..     497     528 ..     477     549 .. 0.82

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.045
      RuvB_N   7 eeyigqekvkeklkifieaakkreeald...hvllyGp....PGlGkttlakiiakelgvklkitsgPvlekagdlaalltn 81 
                 ++y+  ++  ++ +++++ a +r+++ d     +l  p    PG  + t a+  a+e + k k ++gP+++k++  a  l++
  EEA22608.1 165 DDYVDDNDASDSDDLIVKPATSRRSKPDdddMEMLDTPpkskPGRKRKTDAAFDADEDDKKPKKSTGPAVKKQKSAAK-LQE 245
                 689999999999999999888887665412145676662333688899999*******************99887544.444 PP

  == domain 2  score: 16.1 bits;  conditional E-value: 7.4e-06
      RuvB_N  35 hvllyGpPGlGkttlakiiakelgvklkitsg 66 
                  v+++GpPG+Gktt a+++ak  g ++  t +
  EEA22608.1 497 SVMIHGPPGIGKTTAAHLVAKLEGYDVVETNA 528
                 699*****************987777766654 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.1   6.5e-06    0.0062      21      48 ..     490     519 ..     481     555 .. 0.78
   2 ?    0.1   0.0         1   9.5e+02     133     169 ..     564     602 ..     540     603 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 6.5e-06
      AAA_16  21 sgrp..elvllsGesGvGKsslvrellral 48 
                 +g++  ++v+++G++G+GK++ +  +++  
  EEA22608.1 490 DGSGlyRSVMIHGPPGIGKTTAAHLVAKLE 519
                 5566789***************99998643 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 1
      AAA_16 133 derplvlvlDdlqwadeaslqllaaLlrlles.k.pllv 169
                 +++ lvl++D+++   ++++    aL+++++  + pl++
  EEA22608.1 564 QKKNLVLIMDEVDGMSAGDRGGVGALAAAAKKtNiPLIL 602
                 3556*********88887777777777666654445555 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.0   2.8e-06    0.0026       2      32 ..     498     528 ..     498     569 .. 0.82

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 2.8e-06
      AAA_33   2 vllvGlpGsGKstlaerllkklgavllssdt 32 
                 v+++G+pG GK+t a+ ++k +g+ ++++++
  EEA22608.1 498 VMIHGPPGIGKTTAAHLVAKLEGYDVVETNA 528
                 79***************99999999998776 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.1      0.12   1.1e+02      39      73 ..     391     424 ..     335     427 .. 0.80
   2 !   12.0   0.1    0.0002      0.19       2      33 ..     498     530 ..     497     553 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.12
      AAA_28  39 lakgedalpwvedllafaervleeqleeeaaaaan 73 
                 +a+ ++++++ +++ a+ae++++e+++++a+a+a+
  EEA22608.1 391 QAQAKKEAEE-KKIRAMAEEMEQEEKQKAAEAKAR 424
                 3444444555.699999999999999999998765 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 0.0002
      AAA_28   2 ivitGgestGKTtlleaLaar.gypvvpEaare 33 
                 ++i G+++ GKTt +   a+  gy vv+  a +
  EEA22608.1 498 VMIHGPPGIGKTTAAHLVAKLeGYDVVETNASD 530
                 789****************977****9766655 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   1.1e-05      0.01      21     125 ..     498     606 ..     492     616 .. 0.76

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 1.1e-05
      AAA_30  21 avltGpAGtGKttalkalreaweaaggrviglAptgkaAkvLaeelgi...eastiakllkrlkgrarlepg.tllivDEagmv...dtkqlaallkaa 112
                 ++++Gp+G GKtta   ++++   +g++v+    + + +k+L e++ +   ++ +++ + ++ ++ ++ +++  +li DE+  +   d   + al++aa
  EEA22608.1 498 VMIHGPPGIGKTTAAHLVAKL---EGYDVVETNASDTRSKKLVEGSLLgvlDTTSLQGYFSSEGKNVESQKKnLVLIMDEVDGMsagDRGGVGALAAAA 593
                 789**********97776654...589999988888888888876553336999999999888866667777588999**8555255677788999999 PP

      AAA_30 113 ekagakvilvGDe 125
                 +k+++ +il+  e
  EEA22608.1 594 KKTNIPLILICNE 606
                 9999988887665 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   8.4e-05     0.079       1      30 [.     498     530 ..     498     575 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 8.4e-05
      AAA_18   1 IlltGtpGvGKttlakeLskrlgf...gvnlrd 30 
                 +++ G+pG GKtt a+ ++k++g+    +n +d
  EEA22608.1 498 VMIHGPPGIGKTTAAHLVAKLEGYdvvETNASD 530
                 7899****************9988877444444 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.1   5.4e-05     0.051      23     106 ..     496     579 ..     478     583 .. 0.75

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 5.4e-05
                      S-EEEECSTTSSHHHHHHHHHHHSTTTTS-EEEEETTTS.-TTCHHHHHHEBSSSSSTTTSS-BEHH.HHHT.TTSEEEEETGGGS- CS
  Sigma54_activat  23 lsvlitGesGtGKellaraiheaskrkekpfvavncaai.peelleseLFGhekGaFtGAekekkGl.feka.dgGtlfLDeigelp 106
                       sv+i+G  G GK++ a+++ + +      +v+ n +++ +++l+e +L G+ + +      + +G+ +e+  ++ +l +De+  ++
       EEA22608.1 496 RSVMIHGPPGIGKTTAAHLVAKLE---GYDVVETNASDTrSKKLVEGSLLGVLDTTSLQGYFSSEGKnVESQkKNLVLIMDEVDGMS 579
                      589************998887655...5789******886889********977655444444555415544144578899999887 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   9.4e-05     0.089       2      75 ..     498     576 ..     497     580 .. 0.69
   2 ?   -3.1   0.0       7.5   7.1e+03      72     108 ..     643     678 ..     633     704 .. 0.67

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 9.4e-05
                 EEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--...............--------G-SEEEEESGG CS
       AAA_5   2 vlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreik......ngttslvdsplvraaregeilvlDEve 75 
                 v++ GppG+gK++ a  +a++ +  v++ + + dt++++l+ +  +        +++  ++++ v++ ++  +l++DEv+
  EEA22608.1 498 VMIHGPPGIGKTTAAHLVAKLEGYDVVETNAS-DTRSKKLVEGSLLGvldttsLQGYFSSEGKNVESQKKNLVLIMDEVD 576
                 899************99999999998887665.58888888777777433333333333444444455577888888886 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 7.5
                 ESGGG--HHHHHHHHHHHHSSEEE..-SSSEEE---. CS
       AAA_5  72 DEveraesevlnsLlslleerrllleeggelvkaknd 108
                 ++++ +++ vl+sL+   + + ++l ++   vk +++
  EEA22608.1 643 EGLK-IPPPVLDSLIAGTNADIRQLINMLSTVKLDQK 678
                 5554.67777777777777777777666666665554 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   0.00012      0.11       4      74 ..     497     576 ..     495     588 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00012
      AAA_14   4 ilvitGaRrvGKTtllkqlikellvkkesilyinldderdkkladpe........kllelileklke....ekktylflDEiq 74 
                  ++i G+  +GKTt ++ ++k +     ++++ n  d r kkl + +        +l  ++ ++ k+    +k+ +l++DE+ 
  EEA22608.1 497 SVMIHGPPGIGKTTAAHLVAKLEG---YDVVETNASDTRSKKLVEGSllgvldttSLQGYFSSEGKNvesqKKNLVLIMDEVD 576
                 689************998887666...999999999999977553323333334366666666633366667777899***96 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.0     0.001      0.99       1      21 [.     496     516 ..     496     525 .. 0.85
   2 ?    0.9   0.0       0.4   3.8e+02      75      99 ..     560     584 ..     549     615 .. 0.68

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.001
                 SCEEEEC-TTTCHHHHHHHHH CS
       NACHT   1 rlvilqGeaGsGKTtLlqkla 21 
                 r v+++G++G+GKTt ++ +a
  EEA22608.1 496 RSVMIHGPPGIGKTTAAHLVA 516
                 5699***********887665 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.4
                 HHCCSCCCEEEEEE-STT-SS-TCH CS
       NACHT  75 vllelperlLlilDglDelvtdlgq 99 
                 ++ ++++ l+li+D +D +++ ++ 
  EEA22608.1 560 NVESQKKNLVLIMDEVDGMSAGDRG 584
                 56789999*********99986554 PP

>> PTCB-BRCT  twin BRCT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00034      0.32       5      59 ..     311     367 ..     307     370 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00034
                 EECB-TTC.HHHHHHHHHHTT-EEESSEETT-SEEEE.CSS-CHHHHHHHHCT-EEE CS
   PTCB-BRCT   5 vtgysgdd.rkslqklieamGaeyskdltksvTHLic.ksgeGekyekAkkwgipvV 59 
                 +tg+ ++  r++ q l+++ G+++++  + ++ +++   ++  +k +k k+++i+++
  EEA22608.1 311 FTGVLDSLgREEGQSLVKRYGGKVTGAPSSKTSYVVLgSDAGPSKLRKIKEMNIKTI 367
                 5555555569999************************5556668**********987 PP

>> NTPase_1  NTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.1   0.00038      0.36       2      22 ..     498     518 ..     497     580 .. 0.77
   2 ?   -2.2   0.0       3.5   3.3e+03      90     109 ..     559     580 ..     521     612 .. 0.68

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00038
                 EEEE--TTSSHHHHHHHHHHH CS
    NTPase_1   2 vfiTGppGvGKtTlvkkvlel 22 
                 v+i GppG+GKtT  + v++l
  EEA22608.1 498 VMIHGPPGIGKTTAAHLVAKL 518
                 899************998764 PP

  == domain 2  score: -2.2 bits;  conditional E-value: 3.5
                 HHHHHHH-..EEEE---STTGG CS
    NTPase_1  90 rkalsead..viviDEiGkmEl 109
                 ++  s++   v+++DE+  m  
  EEA22608.1 559 KNVESQKKnlVLIMDEVDGMSA 580
                 4444222235999999977765 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.5       0.1        97     128     166 ..     391     429 ..     337     457 .. 0.60
   2 ?    8.9   0.0    0.0012       1.2      20      34 ..     498     512 ..     477     569 .. 0.78
   3 ?   -0.3   2.8       0.8   7.5e+02     111     187 ..     964    1008 ..     904    1031 .] 0.42

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.1
      AAA_11 128 eiskeleklakelrafeeeeekeklkkskekskskleqe 166
                 + ++++e+++k++ra +ee e+e+++k++e ++++  q+
  EEA22608.1 391 QAQAKKEAEEKKIRAMAEEMEQEEKQKAAEAKARRTPQK 429
                 333344444444444444443333333333333333322 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.0012
      AAA_11  20 tliqGPPGtgKTkti 34 
                 ++i+GPPG gKT++ 
  EEA22608.1 498 VMIHGPPGIGKTTAA 512
                 79**********543 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.8
      AAA_11  111 ekvekrlekeekaqlakeiskeleklakelrafeeeeekeklkkskekskskleqerrklkkerkelskeleeaees 187 
                  e v++ +e+                                 ++++ + k+++ ++  k kk++++   ++++a+++
  EEA22608.1  964 EVVDDAIEED--------------------------------EEEELDLKKDKYVKVPKAKKAATKGTAKSKKAKAK 1008
                  2222222221................................11111111111111111111111111111111111 PP

>> AT_hook  AT hook motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   1.8   5.1e-05     0.048       2      12 ..      84      94 ..      83      95 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 5.1e-05
     AT_hook  2 RkRGRPrKaat 12
                +kRGRP+K+a+
  EEA22608.1 84 KKRGRPPKNAE 94
                9********86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1031 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1949  (0.108707); expected 358.6 (0.02)
Passed bias filter:                      708  (0.0394891); expected 358.6 (0.02)
Passed Vit filter:                       140  (0.00780858); expected 17.9 (0.001)
Passed Fwd filter:                        59  (0.00329076); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              19  [number of targets reported over threshold]
# CPU time: 1.25u 0.42s 00:00:01.67 Elapsed: 00:00:00.57
# Mc/sec: 5467.32
//
Query:       EEA22609.1  [L=224]
Description: mitochondrial large ribosomal subunit protein L16, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-30  106.3   0.3    1.4e-30  106.0   0.3    1.1  1  Ribosomal_L16  Ribosomal protein L16p/L10e
  ------ inclusion threshold ------
        0.1   12.6   0.1        0.3   11.0   0.0    1.7  2  HTH_12         Ribonuclease R winged-helix domain


Domain annotation for each model (and alignments):
>> Ribosomal_L16  Ribosomal protein L16p/L10e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.0   0.3   1.6e-34   1.4e-30       4     132 .]      45     173 ..      39     173 .. 0.92

  Alignments for each domain:
  == domain 1  score: 106.0 bits;  conditional E-value: 1.6e-34
                    SXXBSSSXXSSTSXXXSXXXXXESXEEEEES.SXEEEEHHHHHHHHHHHCTCCCCTSXCEEXXSXXXXEEEEE-SS-TTTSSSSXEEEEEEEEEXS CS
  Ribosomal_L16   4 kkyrKsrkryirgvstkgtklefgdygLval.ekgqltaealeaariainrylkkkrgkklwirvfphhpvtkkagedRmgkGkGkpegwvarvki 98 
                     k +K r ++ +g s +gt++ +gdygL+++ ++ ++ a  l+ ++ +i+r+l+   +  l+ rv +++ v   ++e RmgkGkGk+++w+ar+ +
     EEA22609.1  45 SKSPKGRPKMHTGGSMRGTTVVHGDYGLRMKdHDRRVAAFSLKIGEETIRRRLR-GMNYTLYKRVSANIGVYTSGNEMRMGKGKGKFDYWAARIPV 139
                    45555555999********************8899*******************.4444************************************* PP

                    SCEEEEETTXXXSHHHHHHHHHHHHTSSSXEEEE CS
  Ribosomal_L16  99 gqiifeikagvneeiakealrraasKlpiktkiv 132
                     +i+feik++++e+ia+ea+r+aa+Klp+ +++v
     EEA22609.1 140 SRIVFEIKGDIHEKIAREAFRLAAHKLPGMWEFV 173
                    *******888********************9997 PP

>> HTH_12  Ribonuclease R winged-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   3.4e-05       0.3      29      51 ..      87     108 ..      82     119 .. 0.81
   2 ?   -2.1   0.0      0.44   3.9e+03      21      37 ..     144     161 ..     137     175 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 3.4e-05
      HTH_12  29 digeravRyrLrkleergltrrv 51 
                 +ige+++R+rLr ++   l +rv
  EEA22609.1  87 KIGEETIRRRLRGMNY-TLYKRV 108
                 89***********974.355555 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.44
      HTH_12  21 eeLkkr.gydigeravRy 37 
                  e+k    ++i  +a R 
  EEA22609.1 144 FEIKGDiHEKIAREAFRL 161
                 566655588898888885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (224 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       224  (0.0124937); expected 358.6 (0.02)
Passed bias filter:                      192  (0.0107089); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.45
# Mc/sec: 1490.81
//
Query:       EEA22610.1  [L=111]
Description: hypothetical protein PMAA_092340 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (111 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       190  (0.0105974); expected 358.6 (0.02)
Passed bias filter:                      144  (0.00803168); expected 358.6 (0.02)
Passed Vit filter:                         9  (0.00050198); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.27s 00:00:00.67 Elapsed: 00:00:00.44
# Mc/sec: 762.58
//
Query:       EEA22611.1  [L=352]
Description: DNA replication factor C subunit Rfc5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.3e-11   42.9   0.1    9.5e-11   41.7   0.1    1.6  1  DNA_pol3_delta2  DNA polymerase III, delta subunit
    1.3e-06   28.9   0.0    2.6e-06   27.9   0.0    1.5  1  AAA              ATPase family associated with various cellul
    6.3e-06   26.5   0.0      3e-05   24.3   0.0    2.0  2  AAA_22           AAA domain
     0.0011   19.4   0.6     0.0077   16.6   0.3    2.4  2  AAA_16           AAA ATPase domain
     0.0018   18.0   0.2     0.0047   16.7   0.2    1.6  1  AAA_24           AAA domain
     0.0024   18.3   0.1     0.0063   16.9   0.0    1.8  2  Rep_fac_C        Replication factor C C-terminal domain
  ------ inclusion threshold ------
      0.017   15.6   0.1      0.028   14.9   0.1    1.5  1  ABC_tran         ABC transporter
      0.018   15.0   0.0      0.034   14.1   0.0    1.5  1  Rad17            Rad17 P-loop domain
      0.079   12.7   0.0       0.14   11.9   0.0    1.3  1  DNA_pol3_delta   DNA polymerase III, delta subunit
        0.1   11.3   0.0       0.18   10.5   0.0    1.3  1  T4SS-DNA_transf  Type IV secretory system Conjugative DNA tra


Domain annotation for each model (and alignments):
>> DNA_pol3_delta2  DNA polymerase III, delta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.7   0.1   5.3e-14   9.5e-11       4     159 ..      21     184 ..      18     188 .. 0.77

  Alignments for each domain:
  == domain 1  score: 41.7 bits;  conditional E-value: 5.3e-14
  DNA_pol3_delta2   4 ealkilskalksgrlahayLfeGdegigkkelalnlakallceeknetk...pcgecksckkieqgkhpDvivi.....eteekersikldqir 89 
                      e    l++ ++sg + h +L++G++g+gkk+   +  k+l     ++ k      +  s +k+e + +  v ++     +  + +r++  + ++
       EEA22611.1  21 ELSARLKSLAQSGDFPH-LLVYGPSGAGKKTRIIATLKELYGPGVEKIKidaRVFQTTSNRKLEFNIVASVYHLeitpsDVGNYDRVVVQELLK 113
                      56677888889999988.7999999999999999999999976666554334555666666666666666666666554334444466667777 PP

  DNA_pol3_delta2  90 elieels.rkpreskkkiiiiedaekmtksAaNalLktlEEPsenaifiLitsdtnklLktirSRcqelkf 159
                      e+ ++ +  ++   + k+++i++a+++t+ A+ al +t+E  s n  +iL++++t++++ +irSR+  +++
       EEA22611.1 114 EVAQTQQvDQSARQRFKVVVINEADHLTRDAQAALRRTMEKYSPNLRLILLANSTSNIIAPIRSRTLLVRV 184
                      6655444145666899**************************************************98876 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.9   0.0   1.4e-09   2.6e-06       1     124 [.      38     179 ..      38     185 .. 0.77

  Alignments for each domain:
  == domain 1  score: 27.9 bits;  conditional E-value: 1.4e-09
                 EEEESSTTSSHHHHHHHHHHHH...THEEEEEETTTCSSS.............................STTHHHHHHHHHHHHHHHTS..TSEEEEEE CS
         AAA   1 vllyGppGtGKTllakavakel...gvefleisgsellsk.............................yvgesekkirelfkeakeka..kpsilfiD 65 
                 +l+yGp G GK + + a  kel   gve ++i++  +                                +v+e  k+++++ +   ++a  + ++++i 
  EEA22611.1  38 LLVYGPSGAGKKTRIIATLKELygpGVEKIKIDARVFQTTsnrklefnivasvyhleitpsdvgnydrvVVQELLKEVAQTQQV-DQSArqRFKVVVIN 135
                 69*******************955535555555544442245556667777777788888888888888777777777777654.34445444****** PP

                 TGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTSSSTEEEEEEESSGGGSTHHHHSTTS CS
         AAA  66 EidalaksrsgseseeeervvnqLlteldgvkkkeskvivigatnrpdkldpallrgRf 124
                 E+d l+++            +++L + +++++    ++ +i+ +n+ +++  +++ +R 
  EEA22611.1 136 EADHLTRDA-----------QAALRRTMEKYSP---NLRLILLANSTSNIIAPIR-SRT 179
                 *****9888...........***********99...699****************.775 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.3   0.0   1.7e-08     3e-05       7     118 ..      37     154 ..      33     171 .. 0.73
   2 ?   -0.7   0.0      0.89   1.6e+03      52      86 ..     250     282 ..     177     292 .. 0.64

  Alignments for each domain:
  == domain 1  score: 24.3 bits;  conditional E-value: 1.7e-08
      AAA_22   7 ilvvtGesGtGK.Ttllrrlleqldeeakaeeerpevvfvtlpsst..sskdl.lrellralglelka............erlsseellealeqalrar 89 
                 +l+v+G+sG+GK T+ +++l+e +        +++e +++++ +    s ++l ++ +++ ++le               e l++ +  +++ q +r+r
  EEA22611.1  37 HLLVYGPSGAGKkTRIIATLKELYG-------PGVEKIKIDARVFQttSNRKLeFNIVASVYHLEITPsdvgnydrvvvqELLKEVAQTQQVDQSARQR 128
                 799********55**********94.......36666677777776556666655555555555555599****9999955555555558888888888 PP

      AAA_22  90 avielliiDEaqhlrseealeeLrsllnl 118
                 ++  +++i Ea+hl + +a   Lr+ ++ 
  EEA22611.1 129 FK--VVVINEADHL-TRDAQAALRRTMEK 154
                 88..**********.88888888777773 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.89
      AAA_22  52 sskdllrellralglelkaerlsseellealeqal 86 
                 +++ l ++++ ++  e++   ++  +++e+l++ l
  EEA22611.1 250 DWEALISMVADEILAERSP--ARILQVRERLYDLL 282
                 3444444444444444443..55555555555555 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.3   4.3e-06    0.0077      19     133 ..      30     143 ..      21     164 .. 0.55
   2 ?   -0.6   0.0      0.86   1.5e+03     102     126 ..     256     285 ..     179     320 .. 0.59

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 4.3e-06
      AAA_16  19 vrsgrpelvllsGesGvGK.sslvrellralekdggiflrgkcdql..esa..ipysalaqalareellrqlldeaesaeleawrekleealaavpela 112
                 + sg+ + +l++G+sG GK ++++ +l++ l + g+  ++ +++ +  +s+  +++ ++a++    e+      +      +   ++l++++a++++++
  EEA22611.1  30 AQSGDFPHLLVYGPSGAGKkTRIIATLKE-LYGPGVEKIKIDARVFqtTSNrkLEFNIVASVYHL-EITPSDVGN----YDRVVVQELLKEVAQTQQVD 122
                 457888************64999999995.55553333444444442222222333333333311.222222222....23333333444444566666 PP

      AAA_16 113 gaeasrllellkrllallsrd 133
                  ++++r+  ++ + ++ l+rd
  EEA22611.1 123 QSARQRFKVVVINEADHLTRD 143
                 666666666666665555554 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.86
      AAA_16 102 eeala.avpelagaea.....srllellkrl 126
                   ++  + +e ++a +     +rl++ll+++
  EEA22611.1 256 SMVADeILAERSPA-RilqvrERLYDLLTHC 285
                 22222211111111.1233334444444444 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.2   2.6e-06    0.0047       5      92 ..      38     155 ..      35     160 .. 0.75

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 2.6e-06
      AAA_24   5 iliyGpsgiGK.Ttlakel....gpkplfidtekGlksldadkfpdie............................swedfldevvel....aaelady 66 
                 +l+yGpsg+GK T ++++l    gp +  i +++ +       f++ +                             ++++l+ev++     + + +++
  EEA22611.1  38 LLVYGPSGAGKkTRIIATLkelyGPGVEKIKIDARV-------FQTTSnrklefnivasvyhleitpsdvgnydrvVVQELLKEVAQTqqvdQSARQRF 129
                 79********64899999977775555555555532.......222222233345666777888888888889999899999999988999999999** PP

      AAA_24  67 ktlviDtideleelclaevirqneka 92 
                 k++vi  +d+l + + a ++r  ek 
  EEA22611.1 130 KVVVINEADHLTRDAQAALRRTMEKY 155
                 *****************999887775 PP

>> Rep_fac_C  Replication factor C C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       7.3   1.3e+04      42      61 ..     110     131 ..     106     139 .. 0.41
   2 !   16.9   0.0   3.5e-06    0.0063       8      88 .]     257     338 ..     250     338 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 7.3
                 HHHHHGCCS....S-HHHHHHH CS
   Rep_fac_C  42 qlhrvvkeq..eelpeaqklei 61 
                 +l + v +    + +++q+ ++
  EEA22611.1 110 ELLKEVAQTqqVDQSARQRFKV 131
                 3444443331222334444444 PP

  == domain 2  score: 16.9 bits;  conditional E-value: 3.5e-06
                 HHHHHHHH....T-HHHHHHHHHHHHHHC---HHHHHHHHHHHGCCS..S-HHHHHHHHHHHHHHHHHHHCTH-HHHHHHHHHHH CS
   Rep_fac_C   8 eileacln....gdfeeaykklrellvekGysaediltqlhrvvkeqeelpeaqkleilellgeiekrlveGasehlqlsallar 88 
                  +++ +l+    +++ ++++ l  +l  + ++++++l++l   +++ + +++a+k+e+++  +++e+r+  G+    +l+a++a+
  EEA22611.1 257 MVADEILAerspARILQVRERLY-DLLTHCIPPTMVLKTLTFNLIS-K-VDDALKPEVIKWSAFYEHRIKLGSKVIFHLEAFVAK 338
                 55555544555588899999997.99999***********999998.3.99********99**********************96 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   0.1   1.6e-05     0.028      15     100 ..      39     123 ..      35     223 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.6e-05
                 EEEESTTSSH.HHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHHHHHTCHHHHHHHSTTGGTTCB CS
                 xxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  15 aivGenGaGK.StLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvrenesdeeiekalsklglkelkdt 100
                  + G++GaGK + ++++l +l+ p  ++i++d + +++++ ++l+ +i     + ++ p      n++++ ++++l+++ +++  d+
  EEA22611.1  39 LVYGPSGAGKkTRIIATLKELYGPGVEKIKIDARVFQTTSNRKLEFNIVASVYHLEITPSD--VGNYDRVVVQELLKEVAQTQQVDQ 123
                 578******73669******************99999966666666665555554555544..344555555555555555444433 PP

>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   1.9e-05     0.034      47     141 ..      37     137 ..      10     171 .. 0.68

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 1.9e-05
       Rad17  47 iLLisGPsGCgkstvv.kvLskelgiklre.wlnpvslkepdnqksdfkgltekesrf..lsqiesfkeleLkdakylk..lqklGddlrtdkklilve 139
                  LL+ GPsG gk t +   L   +g+ +++  +++  ++ ++n+k +f  +  +       s +  +  + +++    +   q+  + +r   k+++++
  EEA22611.1  37 HLLVYGPSGAGKKTRIiATLKELYGPGVEKiKIDARVFQTTSNRKLEFNIVASVYHLEitPSDVGNYDRVVVQELLKEVaqTQQVDQSARQRFKVVVIN 135
                 59*********99976155666678888763689999**********9877766552244455666655544443332200455566777777777777 PP

       Rad17 140 dl 141
                 + 
  EEA22611.1 136 EA 137
                 75 PP

>> DNA_pol3_delta  DNA polymerase III, delta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   7.8e-05      0.14      59     164 ..     130     225 ..     127     232 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 7.8e-05
                     EEEEEE--.....TT-S-TTHHHHHHHHTTT--SSEEEEEEES.S--HHHHHHHHHTTTEEEEEE----TTTHHHHHHHHHHHTT-EE-HHHHHH CS
  DNA_pol3_delta  59 rivvlknpklltkesklnekllkeLeeylsnlpedtlLiliapkklderkklvklLkkkatvveaktlkeeelkkwiqkraqelglkiekealel 153
                     ++vv++ +      + l+ + +++L +++++++++  Lil a+    +  +++  + +++ +v++  ++e e+   +++ a++++    +e    
      EEA22611.1 130 KVVVINEA------DHLTRDAQAALRRTMEKYSPNLRLILLAN----STSNIIAPIRSRTLLVRVAAPSETEICAVLKSAAAKENWAPCDELNMR 214
                     67777777......6799999**********************....66789***********************************99999999 PP

                     HHHHHTT-HHH CS
  DNA_pol3_delta 154 Llelvennlsa 164
                     +++ ++ nl++
      EEA22611.1 215 IAKESGRNLRR 225
                     99999999986 PP

>> T4SS-DNA_transf  Type IV secretory system Conjugative DNA transfer
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0    0.0001      0.18      38      60 ..      29      51 ..      11      59 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.0001
  T4SS-DNA_transf 38 lntdGdfehvlvvAptrsgKgvg 60
                     l + Gdf+h lv++p+++gK + 
       EEA22611.1 29 LAQSGDFPHLLVYGPSGAGKKTR 51
                     6789****************775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (352 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       666  (0.0371465); expected 358.6 (0.02)
Passed bias filter:                      528  (0.0294495); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 2406.81
//
Query:       EEA22612.1  [L=243]
Description: cytochrome c oxidase assembly protein Cox11, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.2e-61  207.2   0.0    1.9e-61  206.5   0.0    1.3  1  CtaG_Cox11  Cytochrome c oxidase assembly protein CtaG/Cox11


Domain annotation for each model (and alignments):
>> CtaG_Cox11  Cytochrome c oxidase assembly protein CtaG/Cox11
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  206.5   0.0   1.1e-65   1.9e-61       1     151 []      76     230 ..      76     230 .. 0.94

  Alignments for each domain:
  == domain 1  score: 206.5 bits;  conditional E-value: 1.1e-65
  CtaG_Cox11   1 avPlyrvfCeatGlggktekaaae.....ksaavkvdeertevtveFdadvseklpwefkpeqrslevkpGetalafytaknksdkpiigqavysvaPe 94 
                 +vPly+++C++tG++g++ + +++     +s+ + v+++r +++++F+++vs+ lpw+f+p+qr+++v pGetalafyta+nk  ++iig+a+ysv+P+
  EEA22612.1  76 SVPLYKMICQQTGWNGQPVQVHKAgdgdtASRLKPVTDSR-RLRITFNGSVSDVLPWKFTPQQREVRVLPGETALAFYTATNKGPNDIIGVATYSVTPA 173
                 59***************99888777776444466777888.6********************************************************* PP

  CtaG_Cox11  95 eaakyfnKieCFCFeeqkLkpgeevdlpvlFfidpelaedpelkkvkeitLsYtffe 151
                 ++a yf+Ki+CFCFeeqkL++ge+vd+pv+Ffidp++a+dp+++++++itLsYtff+
  EEA22612.1 174 QVAPYFSKIQCFCFEEQKLNAGESVDMPVFFFIDPDFAKDPSMRNIDTITLSYTFFK 230
                 ********************************************************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (243 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       449  (0.0250432); expected 358.6 (0.02)
Passed bias filter:                      377  (0.0210274); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 1605.01
//
Query:       EEA22613.1  [L=263]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.3e-44  150.4   5.8    1.1e-43  149.3   5.8    1.5  1  CENP-Q    CENP-Q, a CENPA-CAD centromere complex subunit


Domain annotation for each model (and alignments):
>> CENP-Q  CENP-Q, a CENPA-CAD centromere complex subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  149.3   5.8   6.2e-48   1.1e-43       2     168 .]      93     256 ..      92     256 .. 0.95

  Alignments for each domain:
  == domain 1  score: 149.3 bits;  conditional E-value: 6.2e-48
      CENP-Q   2 LlrkLarlpfPpatqsdggkekeldfeklldekaaleaqLspelhslelLeaeiekeeralerdyeaLreLeknakaearerkeklkkehvllqesdse 100
                 L+r+L+r+pfPp      +k++ +d+e++l+e++ le+qLs+++ +++lL+ eie+ee++l++++++ +e+eknak+++ erk+++k+eh++l++ d +
  EEA22613.1  93 LERRLPRMPFPP-----LTKDAGFDHESVLNEHRVLETQLSTTRNTIDLLKLEIEREEALLAKETKYVEEMEKNAKKAEVERKRQMKNEHPVLRHIDAH 186
                 89**********.....*****************************************************************************88888 PP

      CENP-Q 101 elslleassdevlgea..sgtvfsdlepeldeellpllqqLgshLesmrgnlaqlegllpalerskaaLq 168
                 + + + +ss+  + +   s+++++++e e  +e+++++ qL++hL+sm+ n a+   l++a+++++aaL+
  EEA22613.1 187 SGDANGSSSSVPFVVLdrSKEQTALCEMEPHREIQSIVMQLNGHLNSMQTNIAPFVALREAITEAQAALD 256
                 888887777744444488***************************************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (263 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1621  (0.0904122); expected 358.6 (0.02)
Passed bias filter:                      700  (0.0390429); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 1896.60
//
Query:       EEA22614.1  [L=450]
Description: HLH transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    7.2e-08   32.3   0.0    1.6e-07   31.2   0.0    1.6  1  HLH         Helix-loop-helix DNA-binding domain
  ------ inclusion threshold ------
       0.11   11.7  13.3        0.2   10.9  13.3    1.3  1  ORC6        Origin recognition complex subunit 6 (ORC6)


Domain annotation for each model (and alignments):
>> HLH  Helix-loop-helix DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.2   0.0   1.8e-11   1.6e-07       1      50 [.     376     424 ..     376     426 .. 0.95

  Alignments for each domain:
  == domain 1  score: 31.2 bits;  conditional E-value: 1.8e-11
                 HHHHHHHHHHHHHHHHHHHHHHHHHCSTCSTTSS-STHHHHHHHHHHHHH CS
         HLH   1 rraahnerErrRRdriNsaleeLrellPslppskKlsKaeiLekAveYIk 50 
                 +r++h + E++RR+ i+++++eL  l+P   ++   sK+++L +A +Y+ 
  EEA22614.1 376 KRTNHILSEQKRRNLIKQGFDELCALVP-ELRGGGFSKSAMLIQAADYLE 424
                 79**************************.789999*************85 PP

>> ORC6  Origin recognition complex subunit 6 (ORC6)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.9  13.3   2.3e-05       0.2      71     222 ..     241     399 ..     232     401 .. 0.66

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 2.3e-05
        ORC6  71 pkaykklldlfrqsLsnsssatstPskspsspst...dpkslrk.qlfsTPtKsktlktalsa...sksssplkrrrklaneedgeeeeedapswvsts 162
                 ++++k+ll+ +++ L +++sat t  ++ ++p     +p++ r+ +  +++  s+++++  ++     ss+p+kr +  ++e++++++++  p + + +
  EEA22614.1 241 EEVAKNLLENMKC-LEPQTSATNTCATNTRAPTPtqfEPPQNREwNIGNGAITSQSSSETTNHgdlDGSSRPRKRSKIKMQEDEDSDNNSTPPRTKKMT 338
                 6799*********.*****88888888777775456644444441444566666666666666999999999998887777777777755544333333 PP

        ORC6 163 ir....dsrpeisrtlspskslgdesilfndss.ddekkseqksprkllkkkk.dkisdediielc 222
                       ++r + s+    sk+l+ ++  +   + ++++ +eqk++ ++l  +k ++  + ++ elc
  EEA22614.1 339 KGasggKARRGSSEN--ASKKLKAQQATK---TaRENLTEEQKRTNHILSEQKrRNLIKQGFDELC 399
                 335775555555554..666666665533...2488999999999995555550555567787777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (450 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1317  (0.0734564); expected 358.6 (0.02)
Passed bias filter:                      576  (0.0321267); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.29s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 2989.13
//
Query:       EEA22615.1  [L=478]
Description: integral membrane protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
     0.0047   17.5   0.4      0.027   15.1   0.3    2.3  2  TMEM135_C_rich  N-terminal cysteine-rich region of Transmembr
  ------ inclusion threshold ------
       0.82   10.2  11.3        0.7   10.4   2.6    2.8  2  HEPN_SAV_6107   SAV_6107-like HEPN


Domain annotation for each model (and alignments):
>> TMEM135_C_rich  N-terminal cysteine-rich region of Transmembrane protein 135
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.0      0.29   2.6e+03      65     118 ..     209     260 ..     154     263 .. 0.63
   2 !   15.1   0.3     3e-06     0.027      13     126 ..     304     427 ..     292     433 .. 0.60

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.29
  TMEM135_C_rich  65 sfltanaalvlvlfcllrrllGklysslvGfgaaliasyiaillerksrrGllt 118
                      +++  aa+v+  +      l + y   +G  a + +  i     r++rrG l 
      EEA22615.1 209 GLFAGSAAIVMWAWFYAPERLPRSYGKWIGEAAQVDGRLIEA--LRRARRGQLV 260
                     333333333333333445567788888888888888877654..4888999875 PP

  == domain 2  score: 15.1 bits;  conditional E-value: 3e-06
  TMEM135_C_rich  13 pscvqsalditrsaleeslkiyaplyliaavlrrrkidyklkklvkeilrsasfltanaalvlvlfcllrrllG.klysslv....Gfgaal... 99 
                     p c   a+      ++ ++    pl l+ +v +++     +++ vk+  rs++fl+   +++    cl+r  +G k++ss+      + + l   
      EEA22615.1 304 PNCEWHAMSRFMRSFKFAMFTNLPLQLLLRVRAKK-PAAAFHRAVKDATRSSTFLALFISMFYYGVCLSRTRIGpKIFSSQTvtplMWDSGLcvg 397
                     55555554443344444433444555555554444.5667*****************99999999*****9999556654321111122222111 PP

  TMEM135_C_rich 100 iasyi...aillerksrrGlltiyvanlat 126
                      + ++   +il e   rr  ++++va  a+
      EEA22615.1 398 AGCFMcgwSILAETAPRRQEIALFVAPRAA 427
                     233442225777777777777777776665 PP

>> HEPN_SAV_6107  SAV_6107-like HEPN
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   2.6   7.8e-05       0.7      16      65 ..     167     216 ..     156     221 .. 0.84
   2 ?    4.0   1.2    0.0078        70       6      34 ..     411     441 ..     407     464 .. 0.74

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 7.8e-05
  HEPN_SAV_6107  16 laAlraAaAvLaargrpe.rrrrrprsaWelLaevaPelaewaalFaagaa 65 
                    l A   Aa v+a  + +e +rr++++  W++++++aP la+ a lFa +aa
     EEA22615.1 167 LFAFTRAARVIASLAWTEwERRQKSKGRWSRVEAIAPRLAD-AGLFAGSAA 216
                    66778899999997777779*******************98.778888876 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.0078
  HEPN_SAV_6107   6 dpaeryaaahlaAlraAaAvLaargrpe..r 34 
                    ++ +r   a   A raAaA+L  r +++  +
     EEA22615.1 411 TAPRRQEIALFVAPRAAAAILPRRYERKylE 441
                    55667777888999*******9988776541 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (478 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       436  (0.0243181); expected 358.6 (0.02)
Passed bias filter:                      339  (0.0189079); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 3446.00
//
Query:       EEA22616.1  [L=520]
Description: Zn cluster transcription factor Rds2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (520 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1327  (0.0740142); expected 358.6 (0.02)
Passed bias filter:                      612  (0.0341346); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.69u 0.28s 00:00:00.97 Elapsed: 00:00:00.48
# Mc/sec: 3290.70
//
Query:       EEA22617.1  [L=171]
Description: hypothetical protein PMAA_092410 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.12   12.9   0.3        8.4    7.1   0.1    2.4  2  Ank_4     Ankyrin repeats (many copies)


Domain annotation for each model (and alignments):
>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.0    0.0088   1.6e+02      24      50 ..      37      65 ..      20      68 .. 0.81
   2 ?    7.1   0.1   0.00047       8.4      35      55 .]      92     112 ..      88     112 .. 0.91

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.0088
       Ank_4 24 gadinaqdn...rsGetalhiAakrgnvei 50
                 ad+++q +   r+++ + ++A+k+++++ 
  EEA22617.1 37 LADPDRQ-DyiaRYHFLCAWMALKNEDIKD 65
                4789999.555588999********99986 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.00047
       Ank_4  35 GetalhiAakrgnveilklLl 55 
                 +++al  A+k+g+ e ++lLl
  EEA22617.1  92 CLSALRLAVKHGYRELAELLL 112
                 5789***************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (171 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       397  (0.0221429); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.29s 00:00:00.72 Elapsed: 00:00:00.43
# Mc/sec: 1189.42
//
Query:       EEA22618.1  [L=120]
Description: hypothetical protein PMAA_092420 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (120 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       580  (0.0323498); expected 358.6 (0.02)
Passed bias filter:                      427  (0.0238162); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.39u 0.23s 00:00:00.62 Elapsed: 00:00:00.39
# Mc/sec: 921.60
//
Query:       EEA22619.1  [L=254]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (254 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       722  (0.04027); expected 358.6 (0.02)
Passed bias filter:                      437  (0.0243739); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.45
# Mc/sec: 1709.66
//
Query:       EEA22620.1  [L=1085]
Description: WD repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.5e-15   57.3   4.9      0.088   13.7   0.0    8.0  8  WD40         WD domain, G-beta repeat
     0.0004   20.6   0.1         14    6.1   0.0    5.2  6  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.1   0.0   0.00013       1.2      12      37 ..     160     187 ..     147     188 .. 0.82
   2 !   13.7   0.0   9.8e-06     0.088       9      37 ..     204     235 ..     198     236 .. 0.82
   3 ?   -2.4   0.1       1.2   1.1e+04      25      37 ..     266     277 ..     247     278 .. 0.64
   4 ?   -3.1   0.2         2   1.8e+04       4      20 ..     314     330 ..     312     343 .. 0.55
   5 !    8.0   0.0   0.00062       5.6       2      37 ..     553     591 ..     552     592 .. 0.75
   6 !    7.7   0.0   0.00078         7       3      35 ..     600     633 ..     598     634 .. 0.87
   7 ?    2.3   0.0      0.04   3.6e+02      25      38 .]     727     742 ..     692     742 .. 0.60
   8 !    8.8   0.0   0.00035       3.2       9      38 .]     754     793 ..     748     793 .. 0.64

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00013
                 SEEEEEEETTSSEEEEE..ETTSEEEEE CS
        WD40  12 svtslafspdgawlasG..sdDgtvriW 37 
                  vts+a sp+g++la G  ++++ v i+
  EEA22620.1 160 AVTSVAISPNGRFLAVGetGYNPRVLIF 187
                 59*************8866668888776 PP

  == domain 2  score: 13.7 bits;  conditional E-value: 9.8e-06
                 SS.SSEEEEEEETTSSEEEE.EET.TSEEEEE CS
        WD40   9 GH.ssvtslafspdgawlas.Gsd.DgtvriW 37 
                  H ++v+slafs+++++la+ G++ Dg + iW
  EEA22620.1 204 EHtFGVRSLAFSSNSQYLATlGDMnDGFLFIW 235
                 59777*************9856325******* PP

  == domain 3  score: -2.4 bits;  conditional E-value: 1.2
                 EEEEETTSEEEEE CS
        WD40  25 lasGsdDgtvriW 37 
                 l++++  ++v++W
  EEA22620.1 266 LITAG-VRHVKVW 277
                 45555.5789999 PP

  == domain 4  score: -3.1 bits;  conditional E-value: 2
                 EEEEESSSSEEEEE.EET CS
        WD40   4 lrtltGHssvtsla.fsp 20 
                 l++l  H   t++a +s+
  EEA22620.1 314 LGSLGEH-TFTCIAsVSD 330
                 6677778.3355542233 PP

  == domain 5  score: 8.0 bits;  conditional E-value: 0.00062
                 EEEEEEESS.SSEEEEE..EETTSSEEEEEETTSEEEEE CS
        WD40   2 qclrtltGH.ssvtsla..fspdgawlasGsdDgtvriW 37 
                 +c+ + ++H + +t++     p   ++as+++D+ v ++
  EEA22620.1 553 KCVNEVRAHgTEITDIVvnSTPGLCLIASSGRDRMVQLF 591
                 8999*****77799998644444444788899**99876 PP

  == domain 6  score: 7.7 bits;  conditional E-value: 0.00078
                 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEE CS
        WD40   3 clrtltGH.ssvtslafspdgawlasGsdDgtvr 35 
                 +++t + H + v  l f  dg  l+s+s D+tv 
  EEA22620.1 600 LIQTMDDHvGAVGQLLFMNDGERLLSCSADRTVI 633
                 6788889988899999****************96 PP

  == domain 7  score: 2.3 bits;  conditional E-value: 0.04
                 EEEE..ETTSEEEEEE CS
        WD40  25 lasG..sdDgtvriWd 38 
                 ++ G  + D+++r++d
  EEA22620.1 727 ILVGvsTTDKSIRVYD 742
                 33354335******98 PP

  == domain 8  score: 8.8 bits;  conditional E-value: 0.00035
                 SS.SSEEEEE.........EETTSSEEEEEETTSEEEEEE CS
        WD40   9 GH.ssvtsla.........fspdgawlasGsdDgtvriWd 38 
                 GH  +v+++           +  g+ l+s + Dg v+iWd
  EEA22620.1 754 GHsEGVSDVIlleqrkpsnPHEVGRILVSTGLDGVVMIWD 793
                 67444777755555444444444555877777*******9 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.1   0.0    0.0016        14      26      57 ..     148     177 ..     144     190 .. 0.83
   2 ?   -1.9   0.0      0.49   4.4e+03      40      56 ..     208     224 ..     203     263 .. 0.70
   3 ?    3.0   0.0     0.014   1.3e+02      31      85 ..     515     566 ..     500     573 .. 0.83
   4 ?   -0.3   0.0      0.15   1.3e+03      33      65 ..     603     635 ..     574     654 .. 0.72
   5 ?    3.3   0.0     0.011        99      51      80 ..     673     702 ..     654     715 .. 0.85
   6 ?   -3.5   0.0       1.5   1.4e+04      54      73 ..     730     749 ..     727     755 .. 0.76

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0016
  ANAPC4_WD40  26 gqrvwtleedkedsevrsLaWkpdgklLavay 57 
                  g r wt    ++ + v+s+a +p+g++Lav+ 
   EEA22620.1 148 GARTWTS--RERIKAVTSVAISPNGRFLAVGE 177
                  5667777..788899***************96 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.49
  ANAPC4_WD40  40 evrsLaWkpdgklLava 56 
                   vrsLa++ + + La  
   EEA22620.1 208 GVRSLAFSSNSQYLATL 224
                  58999999999999875 PP

  == domain 3  score: 3.0 bits;  conditional E-value: 0.014
  ANAPC4_WD40  31 tleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavt 85 
                  +  ed+  +e + L+  +d + ++ +   g +r+l+ae  k+v++++++ ++ +t
   EEA22620.1 515 G--EDEVANELKVLRVAEDANAFVSGDRYGVLRVLSAEPFKCVNEVRAHGTE-IT 566
                  3..477778888899999****************************999885.66 PP

  == domain 4  score: -0.3 bits;  conditional E-value: 0.15
  ANAPC4_WD40  33 eedkedsevrsLaWkpdgklLavaysdgevrll 65 
                  + d++ + v +L + +dg+ L    +d +v + 
   EEA22620.1 603 TMDDHVGAVGQLLFMNDGERLLSCSADRTVIVR 635
                  3577888999***********999999888665 PP

  == domain 5  score: 3.3 bits;  conditional E-value: 0.011
  ANAPC4_WD40  51 klLavaysdgevrlldaesgkvvhslsvks 80 
                    L+ ++ d +++ +d+ sg+ vhs+++++
   EEA22620.1 673 DTLVLSTLDRHIQRFDVASGRHVHSFKATD 702
                  67999999******************9875 PP

  == domain 6  score: -3.5 bits;  conditional E-value: 1.5
  ANAPC4_WD40  54 avaysdgevrlldaesgkvv 73 
                   v++ d ++r++d e   ++
   EEA22620.1 730 GVSTTDKSIRVYDFERDALL 749
                  57888899999998877655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1085 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       624  (0.0348039); expected 358.6 (0.02)
Passed bias filter:                      350  (0.0195214); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.90u 0.36s 00:00:01.26 Elapsed: 00:00:00.59
# Mc/sec: 5575.71
//
Query:       EEA22621.1  [L=536]
Description: glucan endo-1,3-alpha-glucosidase agn1 precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.5e-96  322.8   5.3    3.5e-96  322.3   5.3    1.1  1  Glyco_hydro_71  Glycosyl hydrolase family 71
  ------ inclusion threshold ------
       0.17   12.5   0.0       0.56   10.8   0.0    1.9  2  MCM_N           MCM N-terminal domain
        7.5    6.2   9.5         11    5.6   9.5    1.2  1  PAP1            Transcription factor PAP1


Domain annotation for each model (and alignments):
>> Glyco_hydro_71  Glycosyl hydrolase family 71
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  322.3   5.3  5.8e-100   3.5e-96       1     367 [.      22     406 ..      22     413 .. 0.89

  Alignments for each domain:
  == domain 1  score: 322.3 bits;  conditional E-value: 5.8e-100
  Glyco_hydro_71   1 VfaHfmvgntenytasdwekDiklAkaagiDgFaLNigskdswtaeqladayeaAeavgfkLflSfDmavagawpksevislikkyashpaqlkv 95 
                     VfaH+mvg +   t++++e+Di++A ++g+D+FaLN+ s ++w++e+++++++aAe ++fkLf+SfDm+     + +++  ++k+y +h+ ++ +
      EEA22621.1  22 VFAHYMVGSI---TQKHAETDIQNAINVGFDAFALNLMSLEAWSTEAVDSLFTAAEGTNFKLFFSFDMSH--FTDPAQFLPILKQYVNHDGYYLY 111
                     9*********...99******************************************************7..45569****************** PP

  Glyco_hydro_71  96 ngkplvSTFeGeknaedwasiksal...........teeiffvPdfss..lgaaaaaekaldvvDGlfsWea.Wpkga...tnmstetDeaylsa 173
                     ++kp+vSTF G + +++ +s ++++           ++++ffvPdf++    ++++++ +++vvDG+fsWe+ Wp+ +    n+s ++D+++++a
      EEA22621.1 112 DSKPFVSTFVGGQLTFGLSSPNAGWqssfkaalsdaGVDVFFVPDFDDtsGYPDSFFD-TFTVVDGAFSWESaWPYMDagfANVSDTVDSTMIEA 205
                     ************99999999999999999999999868********997445666666.7************9*987733456************ PP

  Glyco_hydro_71 174 lkg..kpYmmpvSpwffthlgkesynknwvwrgddlwakRweqvlelqpdfveiitWNDygEShYigplkek.kaqdgsskyvegmpHdgwrdll 265
                     +++  k Ymmp+S ++f+hl++    +nw++rg+++++ R+ q+l+l+pd+ve+itWND gE hY+g++ ++   +++  +y+  ++H+gw++++
      EEA22621.1 206 AHNasKIYMMPLSTFQFKHLDT---INNWYRRGESNLYIRMGQILALHPDLVEVITWNDSGEGHYVGNFWNEsLGDTNIAEYAGRFDHTGWQQVI 297
                     *8899***************55...69*****************************************999844455789*************** PP

  Glyco_hydro_71 266 kyyiaayKtgsk...kpaitedklvlwyRphpkkakcssgdttgnpanaelleDkvfvvall...kspatvtvsvggkesetfsvkaGvnklsvp 354
                     +++i+ayK+g++   + + +++  v+wyR+  ++ +c s+d++g p+ +e ++D+++++++l    s+ t++v+++++   t    +G+n +sv 
      EEA22621.1 298 SPFITAYKNGAShlsEITASSNVGVIWYRTLLTTSSC-SDDPIGLPTAHEDAQDAINYAIILpysGSNYTINVYSNNNLIGTAAGVTGLNGGSVL 391
                     **********88865555666666*************.779*********************754555699999998888888888999999998 PP

  Glyco_hydro_71 355 f..ngetGkvkvsvv 367
                         g++ +++v vv
      EEA22621.1 392 GlaAGRANTQRVDVV 406
                     732334444666665 PP

>> MCM_N  MCM N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       2.1   1.3e+04      60      73 ..      91     104 ..      90     105 .. 0.84
   2 ?   10.8   0.0   9.4e-05      0.56      21      58 ..     217     258 ..     165     261 .. 0.72

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 2.1
       MCM_N  60 npkeylplleealk 73 
                 +p ++lp+l++ ++
  EEA22621.1  91 DPAQFLPILKQYVN 104
                 6999*****99875 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 9.4e-05
       MCM_N  21 e....kkYrdqlqemaerekttLevdlddLaafdeeLaeail 58 
                      +k +d +++ ++r++++L++ +  + a  ++L+e i+
  EEA22621.1 217 LstfqFKHLDTINNWYRRGESNLYIRMGQILALHPDLVEVIT 258
                 044449********************************9886 PP

>> PAP1  Transcription factor PAP1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   9.5    0.0019        11     101     164 ..     428     496 ..     392     523 .. 0.61

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.0019
        PAP1 101 aanegltrgstassaesqsstysansgtsts..sdSPsssseshqgqlSScgTSPEPstq....SPaakk 164
                 a+++g+ + + +  a s +++ s +++tsts  s  Ps+ss++ ++ +  + TSP P t+    SP++++
  EEA22621.1 428 AETSGICNYNYEVVAMSGDASASSSKATSTSaiSSTPSTSSTKATS-SPASLTSPTPKTTatasSPTGNP 496
                 3344555556666667777777777778887778888888888755.666789****8761222555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (536 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       986  (0.0549947); expected 358.6 (0.02)
Passed bias filter:                      587  (0.0327403); expected 358.6 (0.02)
Passed Vit filter:                        67  (0.00373696); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.83u 0.39s 00:00:01.22 Elapsed: 00:00:00.59
# Mc/sec: 2731.77
//
Query:       EEA22622.1  [L=300]
Description: mitochondrion organization and biogenesis protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.6e-13   49.2   1.1    6.6e-13   49.2   1.1    1.7  2  Neugrin   Neugrin
    0.00014   22.1  11.5    0.00029   21.0  11.6    1.6  1  MRP-L20   Mitochondrial ribosomal protein subunit L20
  ------ inclusion threshold ------
      0.047   13.8   1.1        0.1   12.7   1.1    1.6  1  Skp1      Skp1 family, dimerisation domain
        2.8    8.6   9.6        4.5    8.0   2.0    2.5  2  US2       US2 family


Domain annotation for each model (and alignments):
>> Neugrin  Neugrin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.5      0.73   3.3e+03     124     132 ..     115     123 ..      84     157 .. 0.50
   2 !   49.2   1.1   1.5e-16   6.6e-13       7      68 ..     164     225 ..     158     265 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.73
     Neugrin 124 slaLkseee 132
                 s   k++  
  EEA22622.1 115 SSKTKTKAA 123
                 111121111 PP

  == domain 2  score: 49.2 bits;  conditional E-value: 1.5e-16
     Neugrin   7 PeRrLtWeaieqiRYLkeefpeeWtvprLaeGFdvstDvirRvlkskfvPtlerklkqDakv 68 
                 P+++L  + ++ iR+L+   p+ Wt p La+ F++s++ irR+lksk+ Pt+e + + + + 
  EEA22622.1 164 PRKKLPPDSLDTIRHLHATKPDVWTTPVLADQFKISPEAIRRILKSKWQPTEEERERREERW 225
                 9999*************************************************999887765 PP

>> MRP-L20  Mitochondrial ribosomal protein subunit L20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0  11.6   6.5e-08   0.00029      66     149 ..     140     228 ..      93     248 .. 0.62

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 6.5e-08
     MRP-L20  66 k......sselPpvlkkkse...kekkyhltkedieeirrLraeDPekwsrkkLakkFgcsklfvsmvteapkekkkeveaeleavkerWgek 149
                 k       ++   +l+kk +   + +k +l ++  + ir+L+a+ P+ w++  La +F++s+  ++ +++ + +  +e   e+e+ +erW e+
  EEA22622.1 140 KkvkrphWQTQKEALEKKFTegwHPRK-KLPPDSLDTIRHLHATKPDVWTTPVLADQFKISPEAIRRILKSKWQPTEE---ERERREERWAER 228
                 223333322222222222222333444.8***************************************9887655544...556666777654 PP

>> Skp1  Skp1 family, dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   1.1   2.3e-05       0.1      12      48 .]     193     226 ..     188     226 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.3e-05
        Skp1  12 AdmikgktpeeiReiFnIenDftpEEeeeirkEneWa 48 
                 Ad++k  +pe iR i++ +   t+EE e  r+E +Wa
  EEA22622.1 193 ADQFK-ISPEAIRRILKSKWQPTEEERE--RREERWA 226
                 78887.59*********87776666666..7777898 PP

>> US2  US2 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.4    0.0068        30      70     116 ..      59     117 ..      33     129 .. 0.62
   2 ?    8.0   2.0   0.00099       4.5      52     114 ..     199     285 ..     171     297 .. 0.71

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0068
         US2  70 aalskleallsakrlvYgvvdp...........ealreeaslr.ppepakrseresske 116
                  ++++ ++++    ++Y+v+             +  ++e s++ p++p+++se+ +s++
  EEA22622.1  59 SFSTSQAFKDGGNIVIYDVIATkapdgdvltelTSTKAEDSPKtPKSPKSSSEKPKSSK 117
                 456667788888999*****99999*988865544555555542233333333333333 PP

  == domain 2  score: 8.0 bits;  conditional E-value: 0.00099
         US2  52 lPdelkplltvewtpfeeaalskleallsakrlvYgvvdp........................ealreeaslrppepakrseress 114
                  P+ ++ +l ++w+p+ee+ + + e    +++ +Y  +++                        + +r++ +++p+++++  e + s
  EEA22622.1 199 SPEAIRRILKSKWQPTEEERERREERWAERYKKIYSHMEElglrrrkgewtakvsdarrlglegKSIRQNFRRKPQARPEGTEINIS 285
                 466999******************************999988877777777777777777776666666666666665555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (300 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1307  (0.0728987); expected 358.6 (0.02)
Passed bias filter:                      528  (0.0294495); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.71u 0.35s 00:00:01.06 Elapsed: 00:00:00.59
# Mc/sec: 1544.34
//
Query:       EEA22623.1  [L=821]
Description: intracellular protein transport protein (Sat1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
   7.5e-142  473.4   0.0   1.7e-141  472.2   0.0    1.6  2  Rgp1        Rgp1
    5.6e-05   23.2   0.1    0.00018   21.6   0.0    1.8  2  Arrestin_N  Arrestin (or S-antigen), N-terminal domain
  ------ inclusion threshold ------
       0.13   11.8   0.0       0.27   10.7   0.0    1.4  1  Spo0M       SpoOM protein


Domain annotation for each model (and alignments):
>> Rgp1  Rgp1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.0      0.43   2.6e+03     319     333 ..      20      34 ..      15      52 .. 0.82
   2 !  472.2   0.0  2.8e-145  1.7e-141       1     416 [.     357     755 ..     357     756 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 0.43
        Rgp1 319 rlgetitlvidfsda 333
                   ge+++++i+f++ 
  EEA22623.1  20 FAGEDVECTITFKNV 34 
                 579*********996 PP

  == domain 2  score: 472.2 bits;  conditional E-value: 2.8e-145
        Rgp1   1 tLlmgYvQisGsftlDgslineskfeevkrkavvggsggvvglekskrssgllgglgwgsiseslgellggnelstlkemresaesksiPllstpqslL 99 
                 tLlmgY+Q+s+sft+Dgslin+s feevkrk+vvgg+ +  + ek +r  g+lg++gw +i+es+++ll++++l+ l++mr+ ++s+siPllstpqslL
  EEA22623.1 357 TLLMGYAQVSASFTVDGSLINQSAFEEVKRKGVVGGQTSGRKQEKPRRAGGFLGAFGWDAIEESISGLLSNGDLEGLRDMRGVTSSNSIPLLSTPQSLL 455
                 79********************************9643444444777888************************************************* PP

        Rgp1 100 fvdLtLaPGEsksFefsfkLPkdLpPsyrgkaikisYsLviGtqrpggak..qqvksvevPirvlpsvnssgeqlghdLmspyillrdearvkevksrk 196
                 fvdL+L PGE+ks++fsf+LP++Lp+sy+gkaikisY+LviGtqrp+g k  qqv++++vP+rv++ vn +g+ lghdLm+py+llrdearv++v+   
  EEA22623.1 456 FVDLRLGPGEEKSYSFSFTLPRGLPASYKGKAIKISYNLVIGTQRPSGPKesQQVNRINVPFRVFSGVNDQGDVLGHDLMQPYVLLRDEARVQKVS--- 551
                 *********************************************999999*********************************************... PP

        Rgp1 197 kssssskekkkskskkkseksesskedFlkyveelleneseskdieellspqlevqfeeeedseeneesrrksvvskesssvkeaidllilrsqla... 292
                      s  ++ +k+k+ s  ++ +  +Fl+yv+e+le+++ ++    l +p   + ++        e +rr+s+   +  ++keai+++ilrs+++   
  EEA22623.1 552 -----SIPRPPQKDKSISGPTWATAPEFLSYVDEILEKHETQN----LRTPGPPIGTP-------VE-RRRSSAGLGPPLTCKEAIEFAILRSNQVtss 633
                 .....56667788999999999****************98885....55555444322.......11.3444444446666**************9543 PP

        Rgp1 293 snlqks...yeIarngkrvAvltLskpaYrlgetitlvidfsdaeklkvyavtatLesfEkidpslalrseasikrvtrkvvaesseitlfarervsfk 388
                 +   +s   ++Iarng+r+Av++L++p +rlget+ ++idf+da +l++ +++atLe++Ek+dpslalrs++si+r+tr+++a+  e+tlf++ rv+f+
  EEA22623.1 634 N---RSanrFDIARNGRRIAVVVLNRPSHRLGETVLATIDFTDA-TLPCFSLRATLETSEKVDPSLALRSNTSIHRATRRIYASYFENTLFST-RVVFS 727
                 3...44456**********************************9.7***********************************************.***** PP

        Rgp1 389 ltipksatpqFkTsgvqlkWllrleFvl 416
                 ++ip satp++ T+g++l+W lr+eFv+
  EEA22623.1 728 PAIPISATPTLLTTGIKLDWDLRFEFVT 755
                 ***************************8 PP

>> Arrestin_N  Arrestin (or S-antigen), N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   0.0       2.4   1.4e+04     112     141 ..      26      56 ..      22      59 .. 0.63
   2 !   21.6   0.0   3.1e-08   0.00018      92     134 ..     467     509 ..     450     518 .. 0.86

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 2.4
                 EEEEEEEEEEEEECCC..E--C.CCEEEEEEE CS
  Arrestin_N 112 aggvrYevkvtldrpw..kidkkkkkvftVir 141
                  ++++++  +++++++  +   +++  + V+r
  EEA22623.1  26 ECTITFKNVAEIAEEKanN-TPQQQHQRRVSR 56 
                 5888888888888887531.223455555555 PP

  == domain 2  score: 21.6 bits;  conditional E-value: 3.1e-08
                 TEEEEEE---TTS--SECSGEEEEEEEEEEEEECCCE--C.CC CS
  Arrestin_N  92 hafpFsfelPknlpsSfeGkaggvrYevkvtldrpwkidkkkk 134
                   ++Fsf+lP+ lp S +Gka ++ Y + +  +rp  ++++++
  EEA22623.1 467 KSYSFSFTLPRGLPASYKGKAIKISYNLVIGTQRPSGPKESQQ 509
                 57****************************9999997776443 PP

>> Spo0M  SpoOM protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   4.5e-05      0.27      80     148 ..     459     527 ..     452     558 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 4.5e-05
                 EEE-TT-EEEEEEEEE--TT-----TT--EEEEEEEEESSS--EEEEEEEEE---HHHHHHHHHHHHTT CS
       Spo0M  80 ftiepgeereipfelelpletPitlggakvwleTeldiagavDpgDkDplevePlplqeavlealeelG 148
                 +++ pgee+++ f+++lp   P + +g+++ ++ +l i  +   g k+  +v+  ++  +v++ ++++G
  EEA22623.1 459 LRLGPGEEKSYSFSFTLPRGLPASYKGKAIKISYNLVIGTQRPSGPKESQQVNRINVPFRVFSGVNDQG 527
                 7899********************************999988888888888887777777777777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (821 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       371  (0.0206927); expected 358.6 (0.02)
Passed bias filter:                      265  (0.0147805); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.80u 0.33s 00:00:01.13 Elapsed: 00:00:00.57
# Mc/sec: 4350.18
//
Query:       EEA22624.1  [L=269]
Description: protein kinase regulator (Mob1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.7e-73  244.2   0.0    9.1e-73  243.8   0.0    1.1  1  Mob1_phocein  Mob1/phocein family


Domain annotation for each model (and alignments):
>> Mob1_phocein  Mob1/phocein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  243.8   0.0   5.1e-77   9.1e-73       2     165 ..      87     253 ..      86     257 .. 0.98

  Alignments for each domain:
  == domain 1  score: 243.8 bits;  conditional E-value: 5.1e-77
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx.. RF
  Mob1_phocein   2 atlgsgdlkeavklPkgedlneWlavhvvdffneinllygtisefcteqscptmsagpkyeYlwade.evkkpvklsApeYidllmdwiesqlnd.. 95 
                   +tlgsg+l++avklP+ged neWlav+vvdf+n+inllyg+i+efc++qscp+m+a++++eYlw+d+ ++k+p+k+sAp Yi++lm wi+ ++++  
    EEA22624.1  87 ETLGSGSLRKAVKLPEGEDVNEWLAVNVVDFYNQINLLYGSITEFCSPQSCPEMKATDEFEYLWQDSeNYKRPTKMSAPAYIEHLMAWIQGNIDNeq 183
                   79****************************************************************955**************************** PP

                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Mob1_phocein  96 lfpskagspfpknflkvvkkilkrlfrvyaHiYihHfeeiaeleleahlntcfkhfvlfvkeFkLidkke 165
                   +fps++g+pfpk+f + +++++krl+rvyaHiY+hH++ i +l+le+hlnt+fkh+vlf++e++L + k+
    EEA22624.1 184 MFPSRTGVPFPKTFPSLIRQMFKRLYRVYAHIYCHHYHVILKLGLEPHLNTSFKHYVLFIDEHNLASGKD 253
                   *****************************************************************99887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (269 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       287  (0.0160076); expected 358.6 (0.02)
Passed bias filter:                      265  (0.0147805); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.35s 00:00:00.94 Elapsed: 00:00:00.54
# Mc/sec: 1492.41
//
Query:       EEA22625.1  [L=217]
Description: protein kinase regulator (Mob1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.6e-73  245.1   0.0    4.6e-73  244.8   0.0    1.0  1  Mob1_phocein  Mob1/phocein family


Domain annotation for each model (and alignments):
>> Mob1_phocein  Mob1/phocein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  244.8   0.0   2.6e-77   4.6e-73       2     165 ..      35     201 ..      34     205 .. 0.98

  Alignments for each domain:
  == domain 1  score: 244.8 bits;  conditional E-value: 2.6e-77
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx.. RF
  Mob1_phocein   2 atlgsgdlkeavklPkgedlneWlavhvvdffneinllygtisefcteqscptmsagpkyeYlwade.evkkpvklsApeYidllmdwiesqlnd.. 95 
                   +tlgsg+l++avklP+ged neWlav+vvdf+n+inllyg+i+efc++qscp+m+a++++eYlw+d+ ++k+p+k+sAp Yi++lm wi+ ++++  
    EEA22625.1  35 ETLGSGSLRKAVKLPEGEDVNEWLAVNVVDFYNQINLLYGSITEFCSPQSCPEMKATDEFEYLWQDSeNYKRPTKMSAPAYIEHLMAWIQGNIDNeq 131
                   79****************************************************************955**************************** PP

                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Mob1_phocein  96 lfpskagspfpknflkvvkkilkrlfrvyaHiYihHfeeiaeleleahlntcfkhfvlfvkeFkLidkke 165
                   +fps++g+pfpk+f + +++++krl+rvyaHiY+hH++ i +l+le+hlnt+fkh+vlf++e++L + k+
    EEA22625.1 132 MFPSRTGVPFPKTFPSLIRQMFKRLYRVYAHIYCHHYHVILKLGLEPHLNTSFKHYVLFIDEHNLASGKD 201
                   *****************************************************************99887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (217 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       320  (0.0178482); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.31s 00:00:00.90 Elapsed: 00:00:00.54
# Mc/sec: 1208.58
//
Query:       EEA22626.1  [L=217]
Description: protein kinase regulator (Mob1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.6e-73  245.1   0.0    4.6e-73  244.8   0.0    1.0  1  Mob1_phocein  Mob1/phocein family


Domain annotation for each model (and alignments):
>> Mob1_phocein  Mob1/phocein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  244.8   0.0   2.6e-77   4.6e-73       2     165 ..      35     201 ..      34     205 .. 0.98

  Alignments for each domain:
  == domain 1  score: 244.8 bits;  conditional E-value: 2.6e-77
                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx.. RF
  Mob1_phocein   2 atlgsgdlkeavklPkgedlneWlavhvvdffneinllygtisefcteqscptmsagpkyeYlwade.evkkpvklsApeYidllmdwiesqlnd.. 95 
                   +tlgsg+l++avklP+ged neWlav+vvdf+n+inllyg+i+efc++qscp+m+a++++eYlw+d+ ++k+p+k+sAp Yi++lm wi+ ++++  
    EEA22626.1  35 ETLGSGSLRKAVKLPEGEDVNEWLAVNVVDFYNQINLLYGSITEFCSPQSCPEMKATDEFEYLWQDSeNYKRPTKMSAPAYIEHLMAWIQGNIDNeq 131
                   79****************************************************************955**************************** PP

                   xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Mob1_phocein  96 lfpskagspfpknflkvvkkilkrlfrvyaHiYihHfeeiaeleleahlntcfkhfvlfvkeFkLidkke 165
                   +fps++g+pfpk+f + +++++krl+rvyaHiY+hH++ i +l+le+hlnt+fkh+vlf++e++L + k+
    EEA22626.1 132 MFPSRTGVPFPKTFPSLIRQMFKRLYRVYAHIYCHHYHVILKLGLEPHLNTSFKHYVLFIDEHNLASGKD 201
                   *****************************************************************99887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (217 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       320  (0.0178482); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.34s 00:00:00.94 Elapsed: 00:00:00.55
# Mc/sec: 1188.66
//
Query:       EEA22627.1  [L=227]
Description: ATP synthase oligomycin sensitivity conferral protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    4.6e-46  157.1   3.3    5.6e-46  156.8   3.3    1.1  1  OSCP       ATP synthase delta (OSCP) subunit
  ------ inclusion threshold ------
      0.012   15.2   0.3      0.015   14.9   0.3    1.1  1  EcoR124_C  Type I restriction and modification enzyme - subun
      0.035   13.9   2.3      0.038   13.8   0.4    2.1  3  DrrA_P4M   DrrA phosphatidylinositol 4-phosphate binding doma


Domain annotation for each model (and alignments):
>> OSCP  ATP synthase delta (OSCP) subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  156.8   3.3   9.3e-50   5.6e-46       1     172 []      46     223 ..      46     223 .. 0.95

  Alignments for each domain:
  == domain 1  score: 156.8 bits;  conditional E-value: 9.3e-50
        OSCP   1 iarrYAkAlfelAkekgaleeveeelealeavlaedkklaellsnpavsaeekkdlleelfke....klseavknflkllaenkRlalLpeiaeefeel 95 
                 ++++YA+Al++++ ++++l++v+++l++l +v+++d+kl  +l+ p++s ++k+++++el         +e++knfl++laen+Rl+lL+ ++e+fe+l
  EEA22627.1  46 VDGTYANALYTASAKTSSLDSVAKSLSQLGEVFKKDPKLTPILNAPTLSVSDKQQIIKELQAVaggaDKNEILKNFLATLAENNRLGLLEGVIEKFETL 144
                 6789*****************************************************99876667778899**************************** PP

        OSCP  96 laeargiveaeVtsavpLtdeqlekleaal..akklgkkkvkleekvdpsliGGvvvkvgdkviDgSvkgkLeklkeqL 172
                 + +++g++e ++tsa++L+++  +++e+a+  ++  + kk+k+ +kv+p+++GG++v++g+++iD Sv++k+++l+++L
  EEA22627.1 145 ISAHKGEIELSITSAQELDNKAIQRIEKAVskSEFSQGKKLKVVTKVNPDVLGGLIVEIGERTIDLSVSSKINRLNKAL 223
                 ******************************6544456679************************************987 PP

>> EcoR124_C  Type I restriction and modification enzyme - subunit R C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   0.3   2.6e-06     0.015     135     225 ..      96     187 ..      81     222 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 2.6e-06
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX...XXXXX CS
   EcoR124_C 135 eereeiekalrssaelrskkdlieefindlkk....kleddkedieeefeefknkekekeleelieeegldeealkkfikeilkrgkfdalgtei 225
                  ++++i+k+l++ a+  +k +++++f+ +l +          e ++e+fe  +++ k +   ++ + ++ld++a+++++k+++k++  +  + ++
  EEA22627.1  96 SDKQQIIKELQAVAGGADKNEILKNFLATLAEnnrlG---LLEGVIEKFETLISAHKGEIELSITSAQELDNKAIQRIEKAVSKSEFSQGKKLKV 187
                 5689**************************8854331...445899*********************************9999999874444444 PP

>> DrrA_P4M  DrrA phosphatidylinositol 4-phosphate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0      0.83   4.9e+03      80      93 ..      59      72 ..      54      81 .. 0.67
   2 ?   13.8   0.4   6.4e-06     0.038      13      60 ..      96     143 ..      85     174 .. 0.88
   3 ?   -1.4   0.0      0.36   2.1e+03      58      58 ..     170     170 ..     143     190 .. 0.53

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.83
                ---HHHHHHHHHHH CS
    DrrA_P4M 80 lkTssvkalekivk 93
                 kTss + + k ++
  EEA22627.1 59 AKTSSLDSVAKSLS 72
                67888877766544 PP

  == domain 2  score: 13.8 bits;  conditional E-value: 6.4e-06
                 TT-TTS-GGGTT--HHHHHHHHHHHHHHHHTT--SHHHHHHHHHHHHT CS
    DrrA_P4M  13 kkskklkekyqklkGDaLKtkILkdfKdkleeistkeeLeklvkefkk 60 
                 ++ +++ +++q++ G a K++ILk+f   l+e +    Le ++++f++
  EEA22627.1  96 SDKQQIIKELQAVAGGADKNEILKNFLATLAENNRLGLLEGVIEKFET 143
                 56788999************************9999999999998875 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.36
                 H CS
    DrrA_P4M  58 f 58 
                 +
  EEA22627.1 170 I 170
                 2 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (227 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       701  (0.0390987); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.64u 0.36s 00:00:01.00 Elapsed: 00:00:00.59
# Mc/sec: 1164.58
//
Query:       EEA22628.1  [L=1030]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.5e-07   29.8   2.6    2.5e-07   29.8   2.6    4.3  4  Glyco_hydro_63  Glycosyl hydrolase family 63 C-terminal domai


Domain annotation for each model (and alignments):
>> Glyco_hydro_63  Glycosyl hydrolase family 63 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.1     0.034     6e+02      85     115 ..     441     471 ..     351     480 .. 0.65
   2 ?   -3.7   0.1      0.21   3.7e+03     186     207 ..     523     544 ..     509     552 .. 0.78
   3 ?   -1.3   0.0     0.038   6.9e+02     253     289 ..     580     614 ..     576     646 .. 0.74
   4 !   29.8   2.6   1.4e-11   2.5e-07     361     488 ..     723     899 ..     716     902 .. 0.68

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.034
                     SBTTTB-SEEHHHHHHHHHHHHHH-HHHHHH CS
  Glyco_hydro_63  85 PsRpfFPRGFlWDeGFhqllilkwdvdltle 115
                     P    +P    WD  Fh ++++  d d++ +
      EEA22628.1 441 PDSWEYPFFAAWDTAFHCIPLSMVDPDFAKK 471
                     5555566667899999999999999998755 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 0.21
                     HHHHHHHHHHHHHHHHHHHHHT CS
  Glyco_hydro_63 186 leflkklyprlkkwfewfrktq 207
                     l+fl++++ +l   f+w+ + +
      EEA22628.1 523 LDFLERVFQKLLLNFTWWVNRK 544
                     6899********9999997765 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.038
                     HHHHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHH CS
  Glyco_hydro_63 253 vDlrsWvalaakslksiaellgeeeekekyaktekel 289
                      D   W+a+   s+ +ia  l ++ ++  y+++++++
      EEA22628.1 580 ADSTGWMAFYCLSMLNIALELAKHRRT--YEDIASKF 614
                     58889************9888776654..55555544 PP

  == domain 4  score: 29.8 bits;  conditional E-value: 1.4e-11
                     T-THHHHHHHHHH-TTTTEETTEEBSB-T...TSTTTT-.....................TT-SSSS-B-HHHHHHHHHHHHHH-.......... CS
  Glyco_hydro_63 361 dsekleklldlikdpeelwsdyGlrslsk...ksslygkrnteh................denYWrgpiWininylilsalkhys.......... 426
                     + ++lek+l+ + d+ e+ sd+G+rslsk   k+++ ++ n ++                 ++ WrgpiWi +n+l++++l +++          
      EEA22628.1 723 SKDRLEKILKRMLDETEFLSDHGIRSLSKyheKNPFSMHVNGQKftvgyvpgdsdsglfgGNSNWRGPIWICVNFLLIESLLRFYmfygdsfkve 817
                     4579************************844345666666654322222222222222224578****************988887889999777 PP

                     ............--SS-.--HHHHHH....HHHHH....HHHHHHHHHHHHTSS--SEE-TTT--EESSSS-TTGGGGHHHH CS
  Glyco_hydro_63 427 ............kvegpykekakeiy....keLrs....nlvnnivkqyketGfvweqYddktGkgkgakeFtGWtslvvli 488
                                 +v+ + +++++++y    +  r+    n + +  +++++  +++e +d  tG+g ga++  GWt l+  +
      EEA22628.1 818 cptgsgdymhlgHVAEELQHRLQHLYvrdyDGRRAindgNDLLDFDEHWRDYLWFYEFFDADTGRGLGASHQCGWTGLLAKV 899
                     775555555555444444777777763221222322112333345679999999**********************998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1030 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       539  (0.030063); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.92u 0.33s 00:00:01.25 Elapsed: 00:00:00.55
# Mc/sec: 5628.39
//
Query:       EEA22629.1  [L=132]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
  ------ inclusion threshold ------
       0.13   11.7   0.0       0.15   11.5   0.0    1.2  1  Esterase_phd    Esterase PHB depolymerase
       0.43    9.9   5.9       0.51    9.7   5.9    1.1  1  DUF4407         Domain of unknown function (DUF4407)
        1.4    8.3   4.8        1.6    8.1   4.8    1.0  1  Plasmodium_Vir  Plasmodium vivax Vir protein


Domain annotation for each model (and alignments):
>> Esterase_phd  Esterase PHB depolymerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   2.6e-05      0.15      49      96 ..      53     104 ..      32     116 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 2.6e-05
  Esterase_phd  49 vlypeqslranaqkcwn.wykdtdraGrGeaavvvalv...dalvdehrvda 96 
                   +l  eq+ +a a++  n   + td+ GrGe++   al     +l deh+ d 
    EEA22629.1  53 LLQQEQAEKAAAKNGDNnTLHGTDQEGRGESDLARALSptsSTLSDEHQSDE 104
                   57889*****99987651667*********9988777522267999999885 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   5.9   8.5e-05      0.51     131     200 ..      29     101 ..       6     127 .. 0.60

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 8.5e-05
     DUF4407 131 ltaelaeleaqiaalqaeidaaearldalraeaqkeldgtk....gtgttgvaGkgpaakekkaqldaaqaela 200
                  +++++  +++++alqa i++ae+ l++++ae ++  +g+     gt  +g +G+ + a++      +++ e +
  EEA22629.1  29 KKQRMTIQTRELEALQARIREAEELLQQEQAEKAAAKNGDNntlhGTDQEG-RGESDLARALSPTSSTLSDEHQ 101
                 456777777788888888888888888888877777777766665444333.5666666664444444444443 PP

>> Plasmodium_Vir  Plasmodium vivax Vir protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1   4.8   0.00026       1.6     210     299 ..      34     120 ..      13     127 .. 0.72

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00026
  Plasmodium_Vir 210 spkeaeeklkqekaaeapellnkekaeqgksekslgseslssekpearkgveeqlvhaltsassgtgndaspesiansssslesvseels 299
                     + +++e    q++  ea+ell++e+ae+   + ++ +  + + ++      e++l+ al+++ss+ +++ + ++ a++s+++  +s+  +
      EEA22629.1  34 TIQTRELEALQARIREAEELLQQEQAEKAAAKNGDNNTLHGTDQEGR---GESDLARALSPTSSTLSDEHQSDEGATDSDTSAATSHDMD 120
                     456666667799999999***99999988888888866666433322...3468999999999999999998888888888877766555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (132 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2213  (0.123431); expected 358.6 (0.02)
Passed bias filter:                      913  (0.0509231); expected 358.6 (0.02)
Passed Vit filter:                       105  (0.00585643); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.61u 0.35s 00:00:00.96 Elapsed: 00:00:00.54
# Mc/sec: 733.17
//
Query:       EEA22630.1  [L=899]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.8e-07   29.8   0.0    9.2e-06   25.6   0.0    2.5  1  Bromodomain  Bromodomain


Domain annotation for each model (and alignments):
>> Bromodomain  Bromodomain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.0   5.1e-10   9.2e-06       4      76 ..     694     812 ..     692     814 .. 0.88

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 5.1e-10
                  HHHHBHTTTCGGGGCSTT-GCCSTTHHHH.SS---HHHHHHHH..HTT--SS...........................................HHH CS
  Bromodomain   4 ilsellehklaepFlepvdpeefpdyyavikkPldLstIkkkl..esnkYks...........................................lad 56 
                  i++++  hk a++F++p++++  p y++ i +P dL+ I+  l   ++                                                 +
   EEA22630.1 694 IMNDVAAHKHASIFSKPLTERDAPGYKDLIYRPQDLKSIRGALsqGNRAVAAateaasssataegespnpsgtpskhaawltktpelippkaivnSSQ 791
                  799999***********************************995555555546778888999999999999999999999999999999999999999 PP

                  HHHHHHHHHHHHHHHSH.TTS CS
  Bromodomain  57 feadlkllfsNarkyng.egs 76 
                  +e++l ++f Na+++n+ ++s
   EEA22630.1 792 LEKELIRMFANAIMFNPaPDS 812
                  999999999999999996666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (899 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       849  (0.0473534); expected 358.6 (0.02)
Passed bias filter:                      383  (0.021362); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.94u 0.39s 00:00:01.33 Elapsed: 00:00:00.58
# Mc/sec: 4707.46
//
Query:       EEA22631.1  [L=426]
Description: diphthamide biosynthesis protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.9e-114  382.2   0.0   2.4e-114  381.9   0.0    1.1  1  Diphthamide_syn  Putative diphthamide synthesis protein


Domain annotation for each model (and alignments):
>> Diphthamide_syn  Putative diphthamide synthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  381.9   0.0  1.3e-118  2.4e-114       1     299 [.     100     399 ..     100     402 .. 0.98

  Alignments for each domain:
  == domain 1  score: 381.9 bits;  conditional E-value: 1.3e-118
  Diphthamide_syn   1 fPegllpdsaeiadileef..gaevvilgDttYGaCcvdevaaehlgadllvHyGhsclspvd..rlpvlYvfveieldvehlvetlkknfkek 90 
                      fPegll ++++i+dil+ef  g+e++i+gD+tYGaCc+d+++a++lg+dllvHy+hscl+pvd  ++++lY+fv+i++d++hl++tl++nf  +
       EEA22631.1 100 FPEGLLLFATTISDILTEFcdGVETLIMGDVTYGACCIDDYTARALGCDLLVHYAHSCLIPVDvtTIKTLYIFVDISIDTTHLLATLERNFVAG 193
                      9***************999899***************************************9999**************************989 PP

  Diphthamide_syn  91 kkivlvstiqyahaleevkeeleeegyevvkvpqsekplspgevlgctspklkeeeeevdailyigdgrfhllslmlsnpklpvyrydpyskkl 184
                      k+i+ v+tiq++ +l+ +k +le++g++v+ +pq  +pls+ge+lgctsp+l+  ++evd +ly+gdgrfhl+s+m++npk+p+yrydpys+ l
       EEA22631.1 194 KTIATVGTIQFNATLHGLKPALERAGFKVI-IPQI-MPLSKGEILGCTSPQLS--DTEVDYLLYLGDGRFHLESAMIHNPKIPAYRYDPYSRVL 283
                      99*********************99*****.****.****************8..669************************************ PP

  Diphthamide_syn 185 teesydakkllrrRyaaiekakdakkvGiivgtlgvqgrlelverlkkllkeagkksylvlvgelnpakLanfaeidafVlvaCprlsiddgke 278
                      ++e+y++++++  R++ai+ a +akk+Gii+g+lg+qg++++++ +++ l++++  ++ +l++e++p kLa++++++++V+vaCprlsid+g++
       EEA22631.1 284 SRETYEHEEMHTLRRDAINAASSAKKWGIILGSLGRQGNPHTMSLIESHLRDKNTPFVNLLLSEIFPGKLASMPDVECWVQVACPRLSIDWGYA 377
                      ********************************************************************************************** PP

  Diphthamide_syn 279 FekPvltpyElevalg.erewt 299
                      F++P+ltpyE+ valg ++ w+
       EEA22631.1 378 FPRPLLTPYEALVALGgKKGWD 399
                      ****************998886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (426 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       391  (0.0218082); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.72u 0.33s 00:00:01.05 Elapsed: 00:00:00.57
# Mc/sec: 2260.34
//
Query:       EEA22632.1  [L=362]
Description: hydroxymethylglutaryl-CoA lyase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    6.1e-45  153.8   0.1    9.6e-45  153.2   0.1    1.3  1  HMGL-like  HMGL-like
  ------ inclusion threshold ------
       0.73   10.2   2.8       0.49   10.7   0.2    2.1  2  PE         PE family


Domain annotation for each model (and alignments):
>> HMGL-like  HMGL-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  153.2   0.1   1.1e-48   9.6e-45       2     262 ..      38     333 ..      37     335 .. 0.91

  Alignments for each domain:
  == domain 1  score: 153.2 bits;  conditional E-value: 1.1e-48
                 -EEEE-TTTHHHHTSSS---HHHHHHHHHHHHHHT-SEE--.......TSGGGT.THHHHHHHS---TT-B.........--EE-SSHHHHHHHHH... CS
   HMGL-like   2 vkivdttLRDGeqalkaalsveeklaiakaLdeagvdeiEv.......gfpaaseddfevvraiakavkkar.......ilalvrarekdikaavealk 86 
                 v+iv++ +RDG q++k+++s+e kl+++  L++ gv  iE+       ++p++     e ++ + k++++++       +++ +r  e+++k+  +   
  EEA22632.1  38 VRIVEVGPRDGLQNEKKSISLETKLELITRLSKTGVTTIEAgsfvpakWVPQMA-STSEILQSLLKTPPQSQnqiaynyLVPNIRGLEDLVKVMEAEGA 135
                 89***************************************************9.7789********99997777778788888888888887665444 PP

                 .TT.........-SEEEEEEES-HHHHHHHHSSTHHHHHHHHHHHHHHHHHTT-E......TTT-BTTTB.S--HHHHHHHHHHHHHHT-SEEEEEETT CS
   HMGL-like  87 gag.........akrvhvfiatselhlkaklkkdreevakkaeeavkaarslgkd......velsledas.rtdleflaevveaaeeaGatriniaDtv 169
                  ag          +++ +f a++e + ka+ +++++e++++++ +v++a+++ ++      v+l++++++ + ++ ++ e++ ++ e+Ga+++++aDt 
  EEA22632.1 136 TAGsrddpnastTTEISLFAAATESFSKANTNCSIDESIERVRPIVALAKEKDIRvrgyvsVALGCPYEGpDVSPGKVSEITATLLEMGADEVSVADTT 234
                 444222222222568****************************************************986489************************** PP

                 S---HHHHHHHHHHHHHHS-.GGGEEEEEB-TTS-HHHHHHHHHHTT--EEEEBTTS--......SSBBB-BHHHHHHHHHHTT-B----HHHHHHHHH CS
   HMGL-like 170 GvltPneaaelisalkervkdkvilsvHcHndlGlAvantlaAveaGadrvdgtvnGlG......eraGnaaleelvaalealgvdtgldlqklrsiaa 262
                 G+ t     el++al++    + +l++H+H+++G+A+ nt++++e G++  d++v GlG      +++Gn+++e+lv +l+ lg++tg+dl+++ +i a
  EEA22632.1 235 GMGTAPRTMELLKALSAAGIANSDLALHFHDTYGQALVNTVVGLEHGIRIFDSSVGGLGgcpyskGATGNVSTEDLVHTLHSLGMHTGIDLEEMSRIGA 333
                 ****************998889************************************************************************99976 PP

>> PE  PE family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.2      0.91   8.2e+03      39      44 ..     153     158 ..     127     167 .. 0.50
   2 ?   10.7   0.2   5.5e-05      0.49      33      68 ..     214     249 ..     210     274 .. 0.78

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 0.91
                 ---SSS CS
          PE  39 vlaaaa 44 
                 + aaa 
  EEA22632.1 153 LFAAAT 158
                 233333 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 5.5e-05
                 HHHHH----SSSSHHHHHHHHHHHHHHHHHHHHHHH CS
          PE  33 aapttavlaaaaDeVSaaiAalfsahaqeyqalsaq 68 
                 ++ t+++l ++aDeVS+a  + +++  ++++ l a 
  EEA22632.1 214 SEITATLLEMGADEVSVADTTGMGTAPRTMELLKAL 249
                 567899************999998888777655554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (362 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       363  (0.0202465); expected 358.6 (0.02)
Passed bias filter:                      329  (0.0183502); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.68u 0.33s 00:00:01.01 Elapsed: 00:00:00.55
# Mc/sec: 1987.43
//
Query:       EEA22633.1  [L=156]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.1e-18   67.4   3.3    1.1e-18   67.4   3.3    2.0  2  DUF1674      Protein of unknown function (DUF1674)
  ------ inclusion threshold ------
      0.052   12.1   2.3      0.062   11.9   2.3    1.0  1  TFIIF_alpha  Transcription initiation factor IIF, alpha subun


Domain annotation for each model (and alignments):
>> DUF1674  Protein of unknown function (DUF1674)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.1      0.43   3.8e+03      11      26 ..      58      73 ..      49      88 .. 0.57
   2 !   67.4   3.3   1.2e-22   1.1e-18       6      50 .]     110     156 .]      76     156 .] 0.93

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.43
     DUF1674 11 epapefegdvnpktgE 26
                e+++ fe+ + + tg 
  EEA22633.1 58 EEQEIFERLQKESTGA 73
                4444555555555554 PP

  == domain 2  score: 67.4 bits;  conditional E-value: 1.2e-22
     DUF1674   6 paaaaepapefegdvnpktgEigGpkgpEPtR...ygDWeykGrvsDF 50 
                 p  +++ +pefegd+npktgE+gGp ++EP+R    gDW+y+Grv+DF
  EEA22633.1 110 PHMREAMKPEFEGDTNPKTGEVGGP-KNEPLRwghQGDWSYNGRVTDF 156
                 67788889*****************.********99************ PP

>> TFIIF_alpha  Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   2.3   6.9e-06     0.062     386     453 ..      35     101 ..      26     121 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 6.9e-06
                  XXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXX..XXXXXX...XXXXXXXXXXXXXXXXXXXXXXXX CS
  TFIIF_alpha 386 eekvdsnessagnsrparpspeqkdskskrkaaseeskspvsvpaKklktenapkssskkslpqtvsk 453
                   +  d+++ss+ +s+pa p   +++ +   ++ ++es  + s+p    k++++p s+++   pq++s+
   EEA22633.1  35 RRVADDSKSSPFGSGPAPPRLPKEEQEIFERL-QKESTGAFSTPRTPPKVNQSPDSQAAATSPQSSSN 101
                  56789****************99997777777.88**********************99999999775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (156 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       438  (0.0244297); expected 358.6 (0.02)
Passed bias filter:                      267  (0.0148921); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.34s 00:00:00.95 Elapsed: 00:00:00.58
# Mc/sec: 810.01
//
Query:       EEA22634.1  [L=478]
Description: acetylornithine aminotransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   3.5e-108  361.9   0.0   4.4e-108  361.5   0.0    1.1  1  Aminotran_3    Aminotransferase class-III
    0.00075   18.8   0.0     0.0014   17.9   0.0    1.4  2  Aminotran_1_2  Aminotransferase class I and II


Domain annotation for each model (and alignments):
>> Aminotran_3  Aminotransferase class-III
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  361.5   0.0  4.9e-112  4.4e-108      12     403 ..      80     469 ..      70     472 .. 0.94

  Alignments for each domain:
  == domain 1  score: 361.5 bits;  conditional E-value: 4.9e-112
                  EEEEEEBTEEEETTS-EEEESSHHHHTTTT-BT-HHHHHHHHHHHTT-S---TTTCEEHHHHHHHHHH..HHHCT-..S...EEEEESSHHHHHHHHH CS
  Aminotran_3  12 vitkaeGvyltdvdgkrylDlvssiavvnlGhahPkvvkavkeqaaklshvsfgaltnepalklaekl..lklapkgld...kvflansGseAvetAl 104
                  v  k++Gvyl+d +++r+lDl+++iav+ lGh++P+++k+++eq ++l h s ++++n  + +l++ l    la +g+    +vf++nsG+eA+e+A+
   EEA22634.1  80 VFVKGQGVYLWDMENRRFLDLTAGIAVNSLGHCDPEIAKVISEQSETLIHAS-NLYHNPWTGALSKLLidETLASGGMRdasQVFVCNSGTEANEAAI 176
                  5679************************************************.88777777777777777455555554466**************** PP

                  HHHHHHHHHTS.HCTT-EEEEETTT---SSHHHHHHSS--TTTTTTCTTB-TSEEEE-TTBGGGTB-HHHHHHHHHHHHHHHHCHTCCCEEEEEE-SC CS
  Aminotran_3 105 Klarkyarekk.atektkiiafkgafHGrtlgalsvtgskkkyktlfgpflpevvrlkypdeevlkeneeeeaalleelealekkkkdevaAvivEpi 201
                  K+ark  ++++ + ek ++++f+g+fHGrt+gals+t + +ky++ f p++p++++ +++d                 +e+le  +++++++vivEpi
   EEA22634.1 177 KFARKVGKTRDaSGEKVELVSFQGSFHGRTMGALSATPN-PKYQQPFAPMVPGFKYGAFND-----------------VEQLESLITEKTCGVIVEPI 256
                  *****9999988999************************.****************99998.................88899999************ PP

                  ETTTTSEB--CCHHHHHHHHHHHHT-EEEEE-TTTTTTTTSSSSGGGGC..........TS--SEEEE-GGGGTTSS-EEEEEEHHHHTTS-TTSB-- CS
  Aminotran_3 202 qgegGvvvaspeflaklrelckkhdvllivDEvqtGfGrTGklfAleha..........gvspDlmtlaKaltgGlplsavlataevmqalapgshgs 289
                  qgegGv+va+pefl +lre c++ +++li+DE+q+G++rTG+++A+ +             +pD++t+aKal++G p+ a++ t++v +a+++g+hg+
   EEA22634.1 257 QGEGGVNVATPEFLIALRERCDQVGAVLIFDEIQCGLSRTGTFWAHGNPaftpkdgskqAAHPDILTTAKALGNGVPIGATIITEKVSSAINTGDHGT 354
                  **********************************************8655667776666799************************************ PP

                  TTTT-HHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHCTT-.TTEEEEEEETTEEEEEEBCCCETTCHHHHHHHHHCTEE-EEETTTEEEE-- CS
  Aminotran_3 290 TfgGnplacavalavleiieeekllenaqelgaalkegLeelqkky.evikevRgkGlmiaielkeeaevkekeilkkakekGvlilsaGdnvirllp 386
                  TfgGnpl c+va+ ++e ++ ++l++ ++ ++a++ +g ++lq+ky + i+evRg+Gl++++ l e+   k +e+l++a++ G+l+++aG+  +r++p
   EEA22634.1 355 TFGGNPLVCRVAHHIVERLAASELQNGVEVKSAQFIAGFKALQEKYpDIIAEVRGVGLILGVQLSEKYASKATEVLTAARQRGLLVITAGEGCLRFVP 452
                  *********************************************************************999************************** PP

                  -TT--HHHHHHHHHHHH CS
  Aminotran_3 387 pliitdeeidelleilk 403
                  +l it+e+i+++l+ l 
   EEA22634.1 453 ALNITEEQIEAGLKVLR 469
                  ************99876 PP

>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0      0.47   4.2e+03      72      87 ..     164     179 ..     140     194 .. 0.67
   2 !   17.9   0.0   1.5e-07    0.0014     129     359 ..     234     464 ..     216     468 .. 0.68

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 0.47
                    EEESHHHHHHHHHHHH CS
  Aminotran_1_2  72 vvgsGagaliealifl 87 
                    v+ sG+ a+ +a++f+
     EEA22634.1 164 VCNSGTEANEAAIKFA 179
                    4445555555555554 PP

  == domain 2  score: 17.9 bits;  conditional E-value: 1.5e-07
                    EE-HHHHHHHHTTHHCTTETEEEEEEESS-TTT--.B--HHHHHHHHHHHHHTTEEEEEEETTTTCBSSSSHTHHH.........HGGSTTSTT.. CS
  Aminotran_1_2 129 hldlealeealkeapegnkktkvilvesphNPtGt.vatleeleklldlakkynlllfvDeaYagfvfgsldavat.........ranveeepn.. 212
                     +d+e+le +++e      kt++++ve ++   G+ vat+e l +l + +++ +++l++De+  g+  +   ++a                  +  
     EEA22634.1 234 FNDVEQLESLITE------KTCGVIVEPIQGEGGVnVATPEFLIALRERCDQVGAVLIFDEIQCGLSRT-GTFWAHgnpaftpkdG------SKqa 316
                    69***********......***************74799999********************9998888.5688888885555333......3333 PP

                    ...EEEEEESSSTTSSGGG-EEEEEEEHHHHHHHHHHHHHHTS..SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS.....TEE CS
  Aminotran_1_2 213 ...llivgslsKafGlaGeRvGyilgnaavvsqlrklsrpfls..ssllqaavaaalsdallkqseleemrqrlqkrrkelrdeLael.....glk 298
                       +    + +Ka+G  G  +G+++++++v s+++    + ++    l+ +++  +++  l      +e +  ++ ++ ++ +++++l     +++
     EEA22634.1 317 ahpD--ILTTAKALG-NGVPIGATIITEKVSSAINTGDHGTTFggNPLVCRVAHHIVER-L----AASELQNGVEVKSAQFIAGFKALqekypDII 404
                    3333..44789**99.58899*************9999999998644445554444444.2....2334444444444444444444444333444 PP

                    EECCSCSSEEEEEETHH...CHHHHHHHHHHTCTEEEEEGGGGTS.TTEEEEEC.TTS-HHHHHHH CS
  Aminotran_1_2 299 vlasqsgmflltdlsae...takelskkLleevgvyvtpgtsftv.pgrlRitv.Aglteeeleel 359
                          g++l + ls++   +a+e+  + +++ g++v+      + +g+lR+ +  + tee++e  
     EEA22634.1 405 AEVRGVGLILGVQLSEKyasKATEVLTAARQR-GLLVIT-----AgEGCLRFVPaLNITEEQIEAG 464
                    44444455555555555444444444445556.666666.....3478888888557777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (478 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       345  (0.0192426); expected 358.6 (0.02)
Passed bias filter:                      340  (0.0189637); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.72u 0.34s 00:00:01.06 Elapsed: 00:00:00.57
# Mc/sec: 2522.34
//
Query:       EEA22635.1  [L=282]
Description: hypothetical protein PMAA_092570 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (282 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       606  (0.0338); expected 358.6 (0.02)
Passed bias filter:                      355  (0.0198003); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.60u 0.35s 00:00:00.95 Elapsed: 00:00:00.55
# Mc/sec: 1544.47
//
Query:       EEA22636.1  [L=264]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (264 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       793  (0.04423); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.62u 0.34s 00:00:00.96 Elapsed: 00:00:00.55
# Mc/sec: 1449.42
//
Query:       EEA22637.1  [L=711]
Description: subtilisin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-44  152.9   0.0    2.3e-44  151.9   0.0    1.5  1  Peptidase_S8  Subtilase family


Domain annotation for each model (and alignments):
>> Peptidase_S8  Subtilase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  151.9   0.0   1.3e-48   2.3e-44       1     291 [.     204     560 ..     204     567 .. 0.83

  Alignments for each domain:
  == domain 1  score: 151.9 bits;  conditional E-value: 1.3e-48
                   -TT-EEEEECS-B-TT-.TTTGGGEEE..EEEE---TTSG.GGEETT-SS-TT-SC-SSS.....HHHHHHHHHH-B....SSSSSB-SSTTSEEE. CS
                   xxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxx..xxxxxxxxxxxxxxxxx. RF
  Peptidase_S8   1 gkgvlvavlDtGvdpsh.pdlsvttdgerklvdvideegagfngadsettstnwarddngnsie.HGthvAGiaaan..apeegekngvapgakil. 92 
                   gkg +v+v+DtG+d++  +d+ +                  f g+  +      a++d  ++++ HGthv+G ++++  ++++g ++g ap a+++ 
    EEA22637.1 204 GKGQIVCVADTGLDKGSnTDVHEA-----------------FSGRIKHLFAWGRAESDLADDLDgHGTHVCGSVLGKgmHNSQGLVQGTAPAADLIv 283
                   89***********87541444432.................233333222222222222222234************9999**************** PP

                   .....EEE-SSTTSB-HH..HHHHHHHHHHHHCT-SEEEE-EESCETTCHHCHHHHHH..HHHHHH.CC.T-EEEEE--SS-T-HH......EEE-T CS
                   .....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxx.xxxxxxxxxxxxxxxx......xxxxx RF
  Peptidase_S8  93 .....svkvldtsggsmetgteliraieeaaedkvdvinmslgestslpktgrsieal..ainravnkk.gvlvviSaGNngktgs......slqag 175
                        ++++l++      ++t+l+  +++a + +++v+ +s+g +    k  r +      i+ +v+++ ++ + ++aGN+g++++      ++ + 
    EEA22637.1 284 qslfsGFNALNQARLGGIPKTNLVPLFDQAYQAGARVHTNSWGSPLPATKIQRPYDGRaeSIDLFVWEHqDMTILFAAGNDGQDADlegkldGTVNP 380
                   *****899988776666677***********************777777766666554669********9************9999***99988889 PP

                   TCEECTTTSTTCEEEEEES.....................................TTSSB-TT--B-TT.......-EEEE-S-CCCCCCCCCHHH CS
                   xxxxxxxxxxxxxxxxxxx.....................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_S8 176 spvgtpstsknvitvgayt.....................................tegkiapfSsrGpssdgklkpdivapGgnivstwsrqsnns 235
                   ++ g+ +++kn itvga++                                     + + +a fSsrGp+++g+lkpdivapG++i+s  s++++ s
    EEA22637.1 381 QSLGAEASAKNCITVGATEnyrpdltsgdenrpytyggfwskrfamnplrddhmanNSEGLAAFSSRGPTTEGRLKPDIVAPGTAILSARSQRQKFS 477
                   99999999************************************************8888*************************999998888776 PP

                   TTTHH........EEEE-SHHHCHHHHHHHHHHHHHHHTT..--HHH...........HHHHHHCCS-EE............S CS
                   xxxxx........xxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxx...........xxxxxxxxxxxx......xxxxxxx RF
  Peptidase_S8 236 aglss........yqsmsGTSmAsPnaagaaAlllsalpk..ltpet...........vraallntAqdl......gkadnie 291
                   a   +        y++ sGTSmA+P++ag+ A+l++al +  + +e            ++a+l+n A ++        a+++ 
    EEA22637.1 478 ARVDQtgksgdnkYMYLSGTSMATPLVAGCCAVLREALLAngYRDERpdgvknptgslIKALLINGAVPIkgqympEGANEAH 560
                   666668899***************************6655587777788899999999*********9998887663333334 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (711 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       387  (0.0215851); expected 358.6 (0.02)
Passed bias filter:                      361  (0.020135); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.78u 0.34s 00:00:01.12 Elapsed: 00:00:00.55
# Mc/sec: 3905.35
//
Query:       EEA22638.1  [L=324]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (324 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       720  (0.0401584); expected 358.6 (0.02)
Passed bias filter:                      545  (0.0303977); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.69u 0.30s 00:00:00.99 Elapsed: 00:00:00.55
# Mc/sec: 1770.60
//
Query:       EEA22639.1  [L=2594]
Description: hypothetical protein PMAA_092610 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
     0.0039   16.7   0.0     0.0087   15.6   0.0    1.5  1  Lactamase_B_2  Beta-lactamase superfamily domain


Domain annotation for each model (and alignments):
>> Lactamase_B_2  Beta-lactamase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   0.0   4.9e-07    0.0087       3      50 ..     114     174 ..     112     203 .. 0.77

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 4.9e-07
                    EEES--TT.................HHHHHTCGGS--SSS--..SEEEEE-SS--HHHHGGGGCC CS
  Lactamase_B_2   3 iLiDagpd.................lrqqalralqPvelrdelppidaVllthaHyDHlaglltl 50 
                    iLiD gp+                 l + +l +l    ++ +++ +d +++th+++DH++g+  +
     EEA22639.1 114 ILIDGGPGnyqihgtrappttplanLYA-MLNTLL---PVGSPNTLDTLVITHDDADHINGIHQV 174
                    7888888888888877777666333222.233333...4679999****************9766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2594 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       818  (0.0456244); expected 358.6 (0.02)
Passed bias filter:                      547  (0.0305092); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 1.52u 0.34s 00:00:01.86 Elapsed: 00:00:00.56
# Mc/sec: 13845.56
//
Query:       EEA22640.1  [L=539]
Description: hypothetical protein PMAA_092620 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00035   21.1   0.2      0.029   14.9   0.0    2.9  3  Ank_2     Ankyrin repeats (3 copies)
     0.0012   19.2   2.5     0.0034   17.8   0.2    2.6  2  Ank       Ankyrin repeat
     0.0061   17.1   0.1      0.038   14.6   0.0    2.3  2  Ank_4     Ankyrin repeats (many copies)
  ------ inclusion threshold ------
      0.025   14.9   0.0        1.9    8.9   0.0    3.1  3  Ank_5     Ankyrin repeats (many copies)
       0.23   12.1   0.9       0.78   10.5   0.1    2.4  2  Ank_3     Ankyrin repeat


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   8.1e-06     0.029      52      83 .]     243     274 ..     196     274 .. 0.69
   2 ?    2.7   0.0     0.054   1.9e+02      11      48 ..     327     368 ..     315     400 .. 0.54
   3 ?   -2.2   0.0       1.8   6.3e+03      47      58 ..     454     465 ..     426     466 .. 0.54

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 8.1e-06
       Ank_2  52 dgrtpLhyAarsghleivklLlekgadinlkd 83 
                 +  t+Lh+A++ +hl iv+ L+ +ga++  +d
  EEA22640.1 243 QMDTALHMASSLTHLGIVQALVHHGANVWYRD 274
                 345*******99**********99**997765 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.054
       Ank_2  11 elvklLl..egadpn..k.ngktaLhyAakngnleivklLleh 48 
                 ++   L    + d+   + ng t++ +A+ +   ++v + l++
  EEA22640.1 327 KVASALTlsGEEDIFvtDeNGTTVISLAVAKM-AKFVVYALAY 368
                 45566644333444454358888888888864.2455555543 PP

  == domain 3  score: -2.2 bits;  conditional E-value: 1.8
       Ank_2  47 ehadndgrtpLh 58 
                 +++ +d  tpLh
  EEA22640.1 454 AKLSQDQLTPLH 465
                 223344556665 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.2   9.4e-07    0.0034       3      27 ..     245     270 ..     244     274 .. 0.89
   2 ?   -0.1   0.2      0.41   1.5e+03       3       8 ..     461     466 ..     459     472 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 9.4e-07
                 BBHHHHHH...HHTTHHHHHHHH.TTTST CS
         Ank   3 nTPLHlAa...tngkkriiklLL.hGAnl 27 
                 +T+LH+A+   + g   i+++L+ hGAn+
  EEA22640.1 245 DTALHMASsltHLG---IVQALVhHGANV 270
                 6******9888888...******88***8 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.41
                 BBHHHH CS
         Ank   3 nTPLHl 8  
                  TPLHl
  EEA22640.1 461 LTPLHL 466
                 6****8 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   1.1e-05     0.038       2      38 ..     245     281 ..     244     287 .. 0.92
   2 ?   -1.4   0.0       1.1     4e+03      17      40 ..     439     465 ..     432     466 .. 0.50

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 1.1e-05
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGeta 38 
                  taLh+a +  +l +v+ L+ +ga++ ++d+ +  ta
  EEA22640.1 245 DTALHMASSLTHLGIVQALVHHGANVWYRDPMDETTA 281
                 599**************************99887777 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 1.1
       Ank_4  17 vrlLlekgadinaq...dnrsGetalh 40 
                 ++ L+ + +++  +   ++ +++t+lh
  EEA22640.1 439 LQTLHLQFPNVRLVeakLSQDQLTPLH 465
                 444444444422222224456788888 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0       1.1   3.9e+03      47      56 .]     211     220 ..     211     220 .. 0.89
   2 ?    8.9   0.0   0.00053       1.9      18      55 ..     246     284 ..     240     285 .. 0.87
   3 ?    1.9   0.0     0.082     3e+02       8      24 ..     339     355 ..     334     357 .. 0.66

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 1.1
       Ank_5  47 srGltaldlA 56 
                 srG+t+l+lA
  EEA22640.1 211 SRGWTVLELA 220
                 689*****98 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.00053
       Ank_5  18 tpLhvAakygaadvvrlLlargadlnltdsrG.ltaldl 55 
                 t+Lh+A++  ++ +v+ L+ +ga+   +d +   ta+++
  EEA22640.1 246 TALHMASSLTHLGIVQALVHHGANVWYRDPMDeTTAVEV 284
                 9******************99999988888887777775 PP

  == domain 3  score: 1.9 bits;  conditional E-value: 0.082
       Ank_5   8 dvnrldgggntpLhvAa 24 
                 d+  +d++g+t++ +A+
  EEA22640.1 339 DIFVTDENGTTVISLAV 355
                 55666777777777765 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.1   0.00022      0.78       4      29 ..     246     270 ..     244     271 .. 0.94
   2 ?   -2.0   0.1       2.5   8.9e+03       2       8 ..     460     466 ..     459     467 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00022
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadv 29 
                 t+Lh+A + ++l iv++L+  +ga+v
  EEA22640.1 246 TALHMASSLTHLGIVQALVH-HGANV 270
                 9*******************.8*997 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 2.5
       Ank_3   2 GetpLhl 8  
                 + tpLhl
  EEA22640.1 460 QLTPLHL 466
                 68****7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (539 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       865  (0.0482459); expected 358.6 (0.02)
Passed bias filter:                      629  (0.0350828); expected 358.6 (0.02)
Passed Vit filter:                        73  (0.00407162); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.65u 0.31s 00:00:00.96 Elapsed: 00:00:00.48
# Mc/sec: 3344.11
//
Query:       EEA22641.1  [L=207]
Description: hypothetical protein PMAA_092630 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (207 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       287  (0.0160076); expected 358.6 (0.02)
Passed bias filter:                      280  (0.0156172); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.22s 00:00:00.68 Elapsed: 00:00:00.43
# Mc/sec: 1434.61
//
Query:       EEA22642.1  [L=783]
Description: lipase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      1e-33  117.0   0.0      2e-23   83.4   0.0    2.6  2  Abhydrolase_3  alpha/beta hydrolase fold


Domain annotation for each model (and alignments):
>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.4   0.0   1.1e-27     2e-23       6     145 ..     220     369 ..     215     399 .. 0.81
   2 !   30.9   0.0   1.3e-11   2.3e-07     113     194 ..     434     518 ..     410     528 .. 0.78

  Alignments for each domain:
  == domain 1  score: 83.4 bits;  conditional E-value: 1.1e-27
                    -STTTS--TTTTHHHHHHHHHHHTSEEEEEE---TTTS-TTHHHHHHHHHHHHHHHTH...HHHT.ETTCEEEEEEETHHHHHHHHHHHHHHHTT- CS
  Abhydrolase_3   6 GGGfvlgsldthdalcrelakelgavvvsvdYrlAPehpfPaavedalaalrwlaeqa...welg.adpsrivlaGdSaGGnlaaavalrardege 97 
                    GGG+v+++++ +d+ +   a ++g+ ++s dY+ APe p+P a++++++++r ++e++     lg +   +i++ GdSaGGnlaa +++++ ++g+
     EEA22642.1 220 GGGYVAMGPRASDDKLLAWAGKTGVPILSLDYKKAPEFPYPYALNECFDVYRSIVESRgrcVGLGgHSRPHIIISGDSAGGNLAAGMTIMILQSGR 315
                    9********999888888***************************************96642333256669**********************987 PP

                    --............EEEEEEESE-SSTSSTTSHHHHHCHHTTTSSSSCHHHHHHHHHHHS CS
  Abhydrolase_3  98 pk............vagqvliyPvtdlertesesikkaeeladgplltraaldlfwrlyl 145
                     +            + g+vliyP++d+ +  s  +     +++ +l++ + ++   + +l
     EEA22642.1 316 TEtrkwmgevplppPDGLVLIYPALDM-NIGSWMT-----EEQMSLIQDRGMRKTNERVL 369
                    7789*******************9999.7644333.....23345555555555555555 PP

  == domain 2  score: 30.9 bits;  conditional E-value: 1.3e-11
                    SSTTSHHHHHCHHT.TTSSSSCHHHHHHHHHHHS.S..GGGGG.STTTSGGGCS-..SST---EEEEEETT-TTHHHHHHHHHHHHHTT CS
  Abhydrolase_3 113 ertesesikkaeel.adgplltraaldlfwrlyl.p..eadrd.dplaspllaed..lsglpptlvvvaefDplrdegeayaerlraag 194
                    +rt  +s+    ++  d  +lt++++++++ ly+ p  + d++ d l+sp+la+d  l+ +p+t+ +++e+Dpl d++  +a r+r+a+
     EEA22642.1 434 TRTAVSSM---LSYfGD-RILTPEMMRAMIILYIgPhnRPDFKtDFLLSPVLAPDaiLAAFPKTYFITGERDPLVDDTVIFAGRIRQAK 518
                    45555666...344255.789*************545545555578*******7678*****************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (783 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       742  (0.0413855); expected 358.6 (0.02)
Passed bias filter:                      450  (0.025099); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.47
# Mc/sec: 5048.32
//
Query:       EEA22643.1  [L=519]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.6e-21   74.8   9.0    1.8e-20   73.9   9.0    1.4  1  Glyco_hydr_30_2  O-Glycosyl hydrolase family 30
    6.7e-08   32.1   1.9    1.1e-07   31.4   1.9    1.4  1  Glyco_hydro_59   Glycosyl hydrolase family 59


Domain annotation for each model (and alignments):
>> Glyco_hydr_30_2  O-Glycosyl hydrolase family 30
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.9   9.0     2e-24   1.8e-20       5     225 ..      65     294 ..      61     315 .. 0.83

  Alignments for each domain:
  == domain 1  score: 73.9 bits;  conditional E-value: 2e-24
                      EEEEEEEEEE--EEEEE-TTTHHHHHHHS-HHHHHHHHHHHH---B-..TTS-B-S---S-EEEE---STTTTTTSS--SS.....STT----S CS
  Glyco_hydr_30_2   5 sidlqeeyqtidsfgasDaWsakfvGkkapeekknkiadlLfsketd..enGnPkGigLslWrfniGaGsteqgeaseitd.....ewrreecf 91 
                      +i+ +++  t + fg s aW ak  G       +  +ad++fs   +  ++    G+gL++ r+n Ga s +  + s ++      + r+ e++
       EEA22643.1  65 TISSTTNWGTWEGFGVSLAWWAKAFG------TRSDLADIFFSATWTtyNEQSIPGMGLTIARYNAGACSWNTVNGSTMAAspsisQSRQMESY 152
                      6888999999****************......57789******875411344456***************998777766541111146778885 PP

                      ....B-TTS-B-TTSSHHHHHHHHHHHHTT---EEEE-SSS-GGGSSSSSSB-S-SS.S-SS-TT-HHHHHHHHHHHHHHH.HCTT--EEEEE- CS
  Glyco_hydr_30_2  92 ....leadGkydwtkqeGqqWflkaakerGveefLgfsnsaPvqmtkngkavstkek.elnlkadkiddfadflvkvadkf.rkegvkfdylsP 179
                          l++  ++ w+  + q+ +l  a++rG + f  fsns+P  m  n +  ++++  + nl+a ++d++a +l+++a++   + gv+f+ +  
       EEA22643.1 153 wldwLNSSSSWSWSVDASQRNMLSMAQSRGANIFELFSNSPPWWMCLNHNPSGSDDGsSNNLQAWNYDQHAVYLATIAQHAaSNWGVSFQSVEA 246
                      4555899*****************************************998877765499********************97788********* PP

                      -S-T-GGG--....SS-B----HHHHHHHHHHHHHHHHHHT-S-EEEEE CS
  Glyco_hydr_30_2 180 vnePqWdwge...gsqeGtpatnediaalvrkLseklsekklktkivlg 225
                      +neP  dw +   g+qeG + + +  a+++ +L ++l++++l++ i+++
       EEA22643.1 247 FNEPSSDWWNgktGTQEGCHFNVSTQATVIGNLRTELNNRRLSS-ILIS 294
                      ****5444433358*************************99875.4444 PP

>> Glyco_hydro_59  Glycosyl hydrolase family 59
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.4   1.9   1.2e-11   1.1e-07     108     257 ..     216     387 ..     131     399 .. 0.80

  Alignments for each domain:
  == domain 1  score: 31.4 bits;  conditional E-value: 1.2e-11
  Glyco_hydro_59 108 ekasektaeylkswlkgakktygldidyiag..................lrnekeydkdyvktlrkaLdkngykkvklvaadeaat.wsiakela 183
                     + +++++a yl+   + a +++g++++ +++                  ++ + +++++ + +lr+ L++++++++ + a+de++  + i++  +
      EEA22643.1 216 AWNYDQHAVYLATIAQHAASNWGVSFQSVEAfnepssdwwngktgtqegCHFNVSTQATVIGNLRTELNNRRLSSILISASDENTYdLAISTWNN 310
                     44567888999999***************99*******999999999987778888999***********************7654466666666 PP

  Glyco_hydro_59 184 kdselkdavdvvglH.ytteksssn.....aealgkplwasEdlssknseegaldlarrinknyvkgkmtkyilwpliaa 257
                       s+ +++v  + +H y+ ++++ +     a++ gk+lw+sE   ++n+ ++  +l++++   +   + t+ ++w++i++
      EEA22643.1 311 LGSAATRNVGRINVHgYQYAEGRRDtlyslASSAGKRLWNSEY--GEND-ATGQTLVTNLLLDFRWLHPTAWVYWQAIDG 387
                     67888888888888864444344323457899999*******9..4444.467788888889999999999999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (519 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       524  (0.0292264); expected 358.6 (0.02)
Passed bias filter:                      341  (0.0190195); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.48
# Mc/sec: 3276.44
//
Query:       EEA22644.1  [L=480]
Description: Golgi integral membrane protein (Cln3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   4.9e-160  532.9   5.1   5.7e-160  532.7   5.1    1.0  1  CLN3      CLN3 protein
  ------ inclusion threshold ------
      0.012   15.9   1.7      0.031   14.6   0.3    2.4  2  DUF1772   Domain of unknown function (DUF1772)


Domain annotation for each model (and alignments):
>> CLN3  CLN3 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  532.7   5.1  6.4e-164  5.7e-160       2     398 .]      59     468 ..      58     468 .. 0.90

  Alignments for each domain:
  == domain 1  score: 532.7 bits;  conditional E-value: 6.4e-164
        CLN3   2 aFwllGLiNNvlyvviLsAAlDlvgkstpkgvvlladilPsllikllapffihkvpysvrvlllvllsalgmllvalsks......lavkllGvvlasl 94 
                 aFw++GLiNNvlyv+iLsAAlDlvg+  pkgvvllad++Ps+++kl+ap+f+h vpy +rvl++++ls++gml++al+++      +++kl+G+vlasl
  EEA22644.1  59 AFWFFGLINNVLYVIILSAALDLVGSGFPKGVVLLADVVPSFITKLTAPYFMHLVPYPIRVLIFAALSVCGMLIIALTPAhtdggsISTKLAGIVLASL 157
                 8******************************************************************************999***************** PP

        CLN3  95 ssGlGEltfLqlthyykksslaawssGTGaaGlvGallyalltsllglsvkatllvslvlPlllllsyflllekkkskkeakaeeee.eeyekleeeee 192
                 ssG GEl+fL+lth+y+++sla+wssGTGaaGlvGa++ya+ t+ lglsvk tll+s++lP+++l+s+f++l+  + + ++ ++ +  +  ++ ++e e
  EEA22644.1 158 SSGAGELSFLGLTHFYGRFSLASWSSGTGAAGLVGAGAYAVATTSLGLSVKFTLLASACLPAIMLVSFFVILPLGPLRLASCEAVQYrSIVNRHDTEVE 256
                 ***************************************************************************998887665444233333333333 PP

        CLN3 193 eee.....eeseeeelleseaasaaeeeeeees.......selkkslkeklklvksLllkymlPLllVYlaeYliNqgvaptllfpleekpfkslrdqY 279
                 +++     e++e+++ll  ++++++       +       s++  s++e+l++ k L++++mlPLllVY+aeY+iNqgv+ptllfpl+e+pf+++r++Y
  EEA22644.1 257 SRHegradETNEQDSLLG-SPERNRPYV----KavesgrvSRAWASFQENLNRSKGLFFPFMLPLLLVYVAEYTINQGVTPTLLFPLKETPFEQYRAFY 350
                 333344322222222222.222222222....13444667788889***************************************************** PP

        CLN3 280 rvyqvlYqlgvfisRssvsllrirklyllsllQvlnlvllllealyelflpsiylvfllilyeGllGGaaYvntfaeiseevekeerefslgavsvsDs 378
                 ++y+++Yq+gvfisRss++++ri++ly++s+lQ++nl++l+l+al+++ +p++yl+fl+i++eGllGG++Yvntfaei ++v++++refsl+a++vsDs
  EEA22644.1 351 PAYNAIYQAGVFISRSSSPFFRIHNLYFPSFLQIANLAILTLHALFNF-IPNVYLIFLIIFWEGLLGGLVYVNTFAEIANRVPAADREFSLAATTVSDS 448
                 **********************************************77.************************************************** PP

        CLN3 379 lGillagllalplenalCkl 398
                  Gi++ag+l++++e++lC++
  EEA22644.1 449 GGICIAGFLGMAFEVWLCRW 468
                 ******************96 PP

>> DUF1772  Domain of unknown function (DUF1772)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.3   3.5e-06     0.031       4      96 ..     123     250 ..     121     274 .. 0.57
   2 ?   -1.6   0.0      0.33     3e+03      28      54 ..     298     326 ..     270     370 .. 0.59

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 3.5e-06
     DUF1772   4 lafslfvvPallslpasssl..........................llkqwrrlfkrg..kavfpplallsalafaylaaraasrgarllylaaaalll 74 
                 +a+s+  + +++ +pa+++                           l +++   f+ +  ++  ++++l+ a a+a+++   +  g +  ++++a+++l
  EEA22644.1 123 AALSVCGMLIIALTPAHTDGgsistklagivlaslssgagelsflgL-THFYGRFSLAswSSGTGAAGLVGAGAYAVAT--TSL-GLSVKFTLLASACL 217
                 56666666666666665555666666666666666666666666642.3333333333113335557777777777444..334.44444447788889 PP

     DUF1772  75 lsivpyTllvmvPtN....nkLaal.......k 96 
                  +i++++++v+ P+     ++++a        +
  EEA22644.1 218 PAIMLVSFFVILPLGplrlASCEAVqyrsivnR 250
                 99***********98643333333354444440 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.33
     DUF1772  28 wrrlfkrg.kavfpplallsalafa..yla 54 
                 +++ ++r    +fp+ +l  +l+++  y+ 
  EEA22644.1 298 FQENLNRSkGLFFPF-MLPLLLVYVaeYTI 326
                 555555552333443.33333333313333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (480 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       486  (0.0271069); expected 358.6 (0.02)
Passed bias filter:                      257  (0.0143343); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.30s 00:00:00.82 Elapsed: 00:00:00.48
# Mc/sec: 3028.74
//
Query:       EEA22645.1  [L=1131]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.8e-43  148.3   0.0    6.2e-43  146.6   0.0    2.0  1  Rxt3      Histone deacetylation protein Rxt3
    0.00062   19.8   0.0     0.0022   18.1   0.0    1.9  2  LCCL      LCCL domain


Domain annotation for each model (and alignments):
>> Rxt3  Histone deacetylation protein Rxt3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  146.6   0.0     7e-47   6.2e-43       1     127 []     928    1048 ..     928    1048 .. 0.93

  Alignments for each domain:
  == domain 1  score: 146.6 bits;  conditional E-value: 7e-47
        Rxt3    1 tvkvprerlkeskreeivarrelWGtdvYtdDSDvvaaliHsGfirgewaedvdvslldlakkkakkkskeekskdeseaekklekkkkrtpvnvpe 97  
                  t++vpr+r+++s+reei+arr++WGt+vYtdDSD+vaa+iHsG+irgew+edvd s+ldl+ k++ ++        + +ae+ +++ k+  p+ +p+
  EEA22645.1  928 TIRVPRFRIDPSHREEICARRAVWGTGVYTDDSDPVAAAIHSGYIRGEWGEDVDISMLDLEIKSDYHHA------PQPTAESGTTTAKPLIPPVPPP 1018
                  8*********************************************************99766555444......6677888889999999****** PP

        Rxt3   98 kkDlhvtlliLpkLekYastvrygikSRew 127 
                  +kDlh+tlliLp+Le+Y+st ++g+kSR+w
  EEA22645.1 1019 NKDLHITLLILPRLERYESTLMFGLKSRAW 1048
                  ****************************** PP

>> LCCL  LCCL domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   2.5e-07    0.0022      34      68 ..     948     983 ..     916    1001 .. 0.81
   2 ?   -3.6   0.0       1.4   1.3e+04      67      90 ..    1026    1049 ..    1021    1052 .. 0.81

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 2.5e-07
                 --EESSSSEETTSBHHHHHHHHTSS.-TT-EEEEEE CS
        LCCL  34 asvvGskvYssdSsICkAAihaGvi.dnkgglvvvt 68 
                   v+G+ vY++dS   +AAih+G i  + g+ v+++
  EEA22645.1 948 RAVWGTGVYTDDSDPVAAAIHSGYIrGEWGEDVDIS 983
                 689**********************65555566655 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 1.4
                  EEEE--B-S---EE-SS-EEE--S CS
        LCCL   67 vtiveelkeykgskqngieSesls 90  
                  + i  +l++y+++  +g++S  ++
  EEA22645.1 1026 LLILPRLERYESTLMFGLKSRAWE 1049
                  667788999**********97765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1131 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       470  (0.0262145); expected 358.6 (0.02)
Passed bias filter:                      182  (0.0101512); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.66u 0.30s 00:00:00.96 Elapsed: 00:00:00.47
# Mc/sec: 7210.82
//
Query:       EEA22646.1  [L=253]
Description: short-chain dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.1e-35  121.4   0.1    4.1e-35  121.0   0.1    1.1  1  adh_short       short chain dehydrogenase
    1.4e-28  100.0   0.0    1.6e-28   99.8   0.0    1.1  1  adh_short_C2    Enoyl-(Acyl carrier protein) reductase
    4.4e-08   33.2   0.3    5.5e-08   32.9   0.3    1.1  1  KR              KR domain
     0.0012   18.7   0.0     0.0018   18.2   0.0    1.3  1  NAD_binding_10  NAD(P)H-binding
  ------ inclusion threshold ------
      0.097   11.8   0.0       0.22   10.7   0.0    1.8  1  NAD_binding_4   Male sterility protein
       0.11   12.0   0.1       0.32   10.4   0.1    1.8  1  Epimerase       NAD dependent epimerase/dehydratase family
       0.19   11.1   0.0        1.9    7.8   0.0    2.0  2  GDP_Man_Dehyd   GDP-mannose 4,6 dehydratase


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.0   0.1   1.6e-38   4.1e-35       3     187 ..       4     203 ..       2     208 .. 0.90

  Alignments for each domain:
  == domain 1  score: 121.0 bits;  conditional E-value: 1.6e-38
                 EEEESTTSHHHHHHHHHHHHTT-EEE....EEESCHHHHHHHHHHHHHT.TSEEEEEE-TTTSHHHHHHHHHHHHHHH..SSESEEEE---S..S--SS CS
   adh_short   3 vlvtGassGIGraiakelakeGakvv....vvdrseekleevakelkee.gakalaiqvDvtdreevealvekavkkl..gkldvLvnNAGi..tgsgp 92 
                 vl+tG s+G+G+a++++l++   +++    +++rs ++  ++ k + +  ++++ ++q+Dvtd ++v a+  ++ +     +ld+L+nNAG   ++ g 
  EEA22646.1   4 VLITGSSRGLGLALVQQLLALPPTTIgtiyATSRSVSPPDALSKLISSSgNNRLKHVQLDVTDPASVTAAATQVSQLSdgRGLDILINNAGTqsERHGR 102
                 9******************9987654222168999999999999998889999*********************99888889**********999999* PP

                 GGGCSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-......TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSH CS
   adh_short  93 fselseeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpv......agvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTd 185
                 +s +s +++e ++ +N+tgv l+t+a+lp ++++++ +Ivn++S+ g  ++      a+v+aY  sKaa+++lt + a ela ++ +v a+ PG ++Td
  EEA22646.1 103 TSAMSLSDFEFTMRLNVTGVHLVTAAFLPLLKAAKGRKIVNITSTLGSIGWshksdiASVPAYKVSKAALNMLTVQYASELAAQNFTVFAISPGWLQTD 201
                 ******************************99999999*********98872222225678*************************************9 PP

                 HH CS
   adh_short 186 ma 187
                 + 
  EEA22646.1 202 LG 203
                 85 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.8   0.0   6.4e-32   1.6e-28      31     184 ..      42     208 ..       8     233 .. 0.84

  Alignments for each domain:
  == domain 1  score: 99.8 bits;  conditional E-value: 6.4e-32
                   HHHHHHHHHHTTSE.E..EE--TTSHHHHHHHHHHHHHHH..SSEEEEEE-----EGCSS-GGGH-HHHHHHHHHHHTHHHHHHHHHHHHHCTSC.. CS
  adh_short_C2  31 kkrveelaeelgae.v..lecDVtdeeqvealveevvekf..gklDilvnnagiapklkgpfletsreefdraldvnlyslfllakaalplmkeg.. 120
                    +++ +l ++ g++ +  +++DVtd+++v+a++ +v +     +lDil+nnag   + +g++  +s ++f+ ++  n+++++l++ a+lpl+k+   
    EEA22646.1  42 PDALSKLISSSGNNrLkhVQLDVTDPASVTAAATQVSQLSdgRGLDILINNAGTQSERHGRTSAMSLSDFEFTMRLNVTGVHLVTAAFLPLLKAAkg 138
                   456777777777664567******************99877689**********************************************7765544 PP

                   CEEEEEEEGGGTSBSTTTT......HHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTT CS
  adh_short_C2 121 gsivnlssvgaervvpnyn......aygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikg 184
                    +ivn++s+ +++++++ +      ay ++Kaal+ lt + A el++++ +v a+spg+++T++  g+++
    EEA22646.1 139 RKIVNITSTLGSIGWSHKSdiasvpAYKVSKAALNMLTVQYASELAAQNFTVFAISPGWLQTDLGGGYAH 208
                   88***********9998766667779**************************************998876 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.9   0.3   2.1e-11   5.5e-08       1     150 [.       2     160 ..       2     181 .. 0.82

  Alignments for each domain:
  == domain 1  score: 32.9 bits;  conditional E-value: 2.1e-11
                 SEEEEETTTSHHHHHHHHHHHH...HHS-EEEEE-SS..--HHHHHHHHHHHHT.T-EEEE----TT-HHHHHHHHHHHHHHS..S---EEEE------ CS
          KR   1 gtylitGGlGgLGlelarwlae...kgarhlvllsRsaaadedskaliaeleal.gaevevvaaDvsdkdavealleeikaee..ppikGvihaAgvlr 93 
                 +++litG   gLGl+l+++l++       ++  +sRs ++ ++   l + ++++ + + + v++Dv+d+++v+a+ +++++    + +   i+ Ag+  
  EEA22646.1   2 ASVLITGSSRGLGLALVQQLLAlppTTIGTIYATSRSVSPPDA---LSKLISSSgNNRLKHVQLDVTDPASVTAAATQVSQLSdgRGLDILINNAGTQS 97 
                 578*****************98665778999******544433...455556662569*********************99777799*********976 PP

                 ..---TTT--HHHHHHHHTTTTHHHHHHHHHTTT....S--SEEEEEEEHHHHH--TT-HHHH CS
          KR  94 ..dklleemtaedleqvlapKvkGawnLhelled....esldffvlfSSiagllgsagqanYa 150
                    +  + m+ +d+e  ++  v+G++ +  ++ +     +   +v ++S  g +g  ++++ a
  EEA22646.1  98 erHGRTSAMSLSDFEFTMRLNVTGVHLVTAAFLPllkaAKGRKIVNITSTLGSIGWSHKSDIA 160
                 2267899********************999987766556777788888888877777766655 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0   7.1e-07    0.0018       1     159 [.       8     211 ..       8     222 .. 0.71

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 7.1e-07
                     TTTSHHHHHHHHHHHHC-...T-EEEEEETT...HHHCHHHH...CTTTCEEEE--TT-CCHHHHHHT.........T-SEEEES---TCC.... CS
  NAD_binding_10   1 GAtGkvGrllvkellarg...ghevtalvRn...peklaele...aeeglevvegdvtdvedlaealk.........gadaVvsalggggk.... 73 
                     G + + G +lv++lla       ++ a  R+   p+ l++l     +++l+ v++dvtd++++++a +         g d+ + ++g++++    
      EEA22646.1   8 GSSRGLGLALVQQLLALPpttIGTIYATSRSvspPDALSKLIsssGNNRLKHVQLDVTDPASVTAAATqvsqlsdgrGLDILINNAGTQSErhgr 102
                     677888999999999998654334455556555577777665444679*******************989999999999*******888775554 PP

                     HHHH.....................HHHHHHHHHHCT--EEEEEEE.TTT.TSGCGCHHHHHHH.HCCHHHHHHHH.HHHHHHHHSSSEEEEEEE CS
  NAD_binding_10  74 deeg.....................aknivdaakeagvkRfvlvsa.igv.gdevpgefgewnk.ellkaylaakr.aaeellrasgldwTivrp 143
                     +  +                     +++ +  +k+a+ +++v +++ +g+ g +++++  ++   ++ ka+l   + + + +l a +++   ++p
      EEA22646.1 103 T--SamslsdfeftmrlnvtgvhlvTAAFLPLLKAAKGRKIVNITStLGSiGWSHKSDIASVPAyKVSKAALNMLTvQYASELAAQNFTVFAISP 195
                     1..145777778888999998888888889999********99987334313333444333322134444443333134446888999999**** PP

                     -CEE-ST--SEEEEET CS
  NAD_binding_10 144 ggLtdepttkyrvvek 159
                     g+L+ + +++y  +  
      EEA22646.1 196 GWLQTDLGGGYAHLRP 211
                     ***9999888887654 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   8.4e-05      0.22       1      55 [.       6      62 ..       6     181 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 8.4e-05
                   EE-TTSHHHHHHHHHHHHHS-.T..EEEEEE-SSSHHHHHHHHHHHT-SS-HHHHHH CS
  NAD_binding_4  1 lTGaTGFLGkvLlekLLrttpev..kiyllvRaksgesaeeRleeelekkelfsall 55
                   +TG++  LG  L+++LL   p    +iy+  R+ s  +a+ +l ++  +++l+++ l
     EEA22646.1  6 ITGSSRGLGLALVQQLLALPPTTigTIYATSRSVSPPDALSKLISSSGNNRLKHVQL 62
                   7999999***********999888*******************88888777776664 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.1   0.00012      0.32       1      63 [.       4      77 ..       4     194 .. 0.61

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00012
                EEEETTTSHHHHHHHHHHHHCTSEEEEEES-...STTTTCHHCHHC............EEEE--TT-HHHHHHHHHHH CS
   Epimerase  1 ilVtGatGfiGsalvkallekgyevigldrl...ssasntarledl............elveldltdrsalerlfkee 63
                +l+tG +  +G alv++ll+   + ig       s + + a    l            + v+ld+td+++++++  ++
  EEA22646.1  4 VLITGSSRGLGLALVQQLLALPPTTIGTIYAtsrSVSPPDA----LsklisssgnnrlKHVQLDVTDPASVTAAATQV 77
                79********************6655544440003333333....13447*******************666655443 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   0.0   0.00073       1.9       1      73 [.       5      76 ..       5      80 .. 0.82
   2 ?    1.2   0.0     0.074   1.9e+02     151     170 ..     163     182 ..     106     193 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.00073
                   EEETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHHH CS
  GDP_Man_Dehyd  1 LiTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkgDltDssslerllae 73
                   LiTG +   G  l+++Ll+   + +g++  +s  +++  ++l k  +++ +++lk ++ D+tD +s++ +  +
     EEA22646.1  5 LITGSSRGLGLALVQQLLALPPTTIGTIYATSR-SVSPPDALSKLISSSGNNRLKHVQLDVTDPASVTAAATQ 76
                   899999889*****************9876665.556666666666677789**************9987655 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.074
                    SHHHHHHHHHHHHHHHHHHH CS
  GDP_Man_Dehyd 151 sPYaaaKlyadwivvnyrea 170
                      Y ++K++ ++++v+y  +
     EEA22646.1 163 PAYKVSKAALNMLTVQYASE 182
                    579*************9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (253 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       413  (0.0230353); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.50u 0.31s 00:00:00.81 Elapsed: 00:00:00.48
# Mc/sec: 1594.48
//
Query:       EEA22647.1  [L=397]
Description: monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-08   34.6   0.0    7.8e-08   31.9   0.0    2.2  1  FAD_binding_3  FAD binding domain


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.9   0.0   4.4e-12   7.8e-08     151     318 ..     156     337 ..      67     362 .. 0.63

  Alignments for each domain:
  == domain 1  score: 31.9 bits;  conditional E-value: 4.4e-12
                    EEEEEEEEEE--GTT-HHHHHHTGG.EEEEEEEEEEEEEEEEEEC.-SCCCTTCCEEEEECCTTEE.................EEEECCETEEEEE CS
  FAD_binding_3 151 etvrakYlvGaDGgrStvrktlgie.fegeetvyeagvldvlfda.dlsdiveplvlilsaesrgv.................mviPlentlerfy 227
                    +t +++ lv+aDG+ S +r++   + ++++      ++ ++   +  l+++ ++ ++++ ++ +gv                 +++P         
     EEA22647.1 156 TTQDCDLLVAADGADSNIRACFRPKdMKTKYAG-ATQIGGISRLTgLLPKPIDKDYVLQMSSGEGVcciynpfdkdtiawavsTIGPE-------- 242
                    3679***************99987755555432.444444544444555555556777777777654533333333334433334443........ PP

                    EEEECCE-GGGSCCCHHHHHHHHHHHHHHTTSSCEE.EEEEE.......EEEEEEEEEESSSEET.....TEEE-GGGTEEE-STTSHHHHHHHHH CS
  FAD_binding_3 228 vqvearaekeersekfteeevkarlreivgektldv.eieev.......sawtvaqrvaekyrkg.....rvflaGDAaHihpPtgGqGlNtaiqD 310
                             +e +++f+e+e  +  +e+ +++ +   +++ v       +a+   ++    +r+g      v  +GDA Hi +P   +G N+a++D
     EEA22647.1 243 ---------REAKTNFNEQEFETLKKEALETASMFQePFKTVveatipnTAFIRPAKEKYAFRHGdtslkGVIFIGDANHILSPYEFVGANLALKD 329
                    .........344444444444443333333333222111111000000011111111122233332122258889********************* PP

                    HHHHHHHH CS
  FAD_binding_3 311 avnLawkL 318
                      +La ++
     EEA22647.1 330 GWDLAEQI 337
                    98888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       453  (0.0252663); expected 358.6 (0.02)
Passed bias filter:                      435  (0.0242624); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.24s 00:00:00.71 Elapsed: 00:00:00.39
# Mc/sec: 3075.23
//
Query:       EEA22648.1  [L=341]
Description: aldo-keto reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.5e-65  221.3   0.0    1.8e-65  221.1   0.0    1.0  1  Aldo_ket_red  Aldo/keto reductase family
  ------ inclusion threshold ------
      0.048   13.1   0.0      0.093   12.1   0.0    1.4  2  Evf           Virulence factor Evf


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  221.1   0.0     2e-69   1.8e-65       1     291 [.      15     329 ..      15     331 .. 0.92

  Alignments for each domain:
  == domain 1  score: 221.1 bits;  conditional E-value: 2e-69
                   .EEEE-SSS-ST.....TS-HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH-TTTGGG-EEEEEE..................--SSS CS
  Aldo_ket_red   1 elglGtwqlgsk....eeiskeealellrraleaGinffDtAevYgkgqseellGealkksrkkreeviiatKv..................dlrda 75 
                   +++lG + +gs+    +++++e++l l+ +a+++Gin++DtA+ Y +g se+++G+alkk++ +r+ v+i tK+                  ++++ 
    EEA22648.1  15 KVILGCMGFGSPewagWVMDEEKSLPLIYHAYQRGINTWDTADCYSNGVSEIIVGKALKKYSIPRQRVVIKTKLytgvddeggqtpihlaqnNDGTW 111
                   5899999999999999**************************************************************************7777777 PP

                   TTSSSS-HHHHHHHHHHHHHHHT-S-EEEEEE-S--TTS-.HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHH....HHTTT--EEEEE-B-BTT- CS
  Aldo_ket_red  76 eiksglskeniresleeslkrLgtdyvDllllHrpdpslpsieevldaleelvkeGkiraiGvSnfsveqleka....kkkkkvkivavqveynllr 168
                    +++gls++ i+ +++es+krLgt y+D+l++Hr d+++p +ee+++al+++v++Gk+r+iG S+  ++  +++     + + +k+++ q  y+l  
    EEA22648.1 112 VNRVGLSRKKIIDAVDESVKRLGT-YIDVLYIHRLDRQTP-REEIMRALNDVVESGKVRYIGASSMRAWEFQALqnvaIQNNWHKFIVMQSYYSLIG 206
                   78899******************6.***************.***********************888888888888899****************** PP

                   HHHHTTHHHHHHHTT-EEEEBSTTGGGTTGTTTSS---SSSCCC-------...TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTSTT-SEEEE CS
  Aldo_ket_red 169 eleeegllelckkkgvpliaysplggGlltgkyqseedkedkeprkdlkrd...ertsknldaaeelselakehgvslaqlalryalsqpavgivip 262
                   ++ee++++++ck+ g++l+++spl++G l + +++ ++   ++++  +k      + +     +++++++ak +gvs+aq+a++++   + ++++ +
    EEA22648.1 207 REEEREMIPYCKDAGIGLVPWSPLARGVLARPWTERDSNR-ETTDIAMKLLvrmRESEADKAIVNRVENIAKAKGVSMAQIAIAWLH--YHGTFPAL 300
                   ******************************9888655533.33333333335558888888999***********************..9******* PP

                   --SSHHHHHHHHGGGG----HHHHHHHHH CS
  Aldo_ket_red 263 gasnieqlednldalelklseeevaelde 291
                   g  ++e++++ ++al++kl+eeev+el+e
    EEA22648.1 301 GLNSPERIDEAVAALQVKLTEEEVKELEE 329
                   **************************987 PP

>> Evf  Virulence factor Evf
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0     1e-05     0.093     143     224 ..     120     204 ..      93     210 .. 0.78
   2 ?   -3.7   0.0       0.7   6.3e+03      16      37 ..     267     288 ..     264     291 .. 0.71

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 1e-05
         Evf 143 asvieavg..vedkvvyipklklykidfdrtnsevvsncas.neninvefeysslislldyqaledpeiktafdnfilknkkssi 224
                  ++i+av   v+    yi  l ++++d ++   e++ +     e  +v ++ +s +  +++qal++  i+  +++fi+ +  +s+
  EEA22648.1 120 KKIIDAVDesVKRLGTYIDVLYIHRLDRQTPREEIMRALNDvVESGKVRYIGASSMRAWEFQALQNVAIQNNWHKFIVMQSYYSL 204
                 46788885114444579**********9999999987654314666899999**************************9988875 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 0.7
         Evf  16 qlsdkaevikklneikkiqial 37 
                  +++++e i k + ++ +qia+
  EEA22648.1 267 AIVNRVENIAKAKGVSMAQIAI 288
                 5667777788888888888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (341 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       520  (0.0290033); expected 358.6 (0.02)
Passed bias filter:                      464  (0.0258799); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.30s 00:00:00.81 Elapsed: 00:00:00.47
# Mc/sec: 2165.94
//
Query:       EEA22649.1  [L=351]
Description: proline racemase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.8e-47  160.6   0.0    7.3e-47  160.0   0.0    1.3  1  Pro_racemase  Proline racemase


Domain annotation for each model (and alignments):
>> Pro_racemase  Proline racemase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  160.0   0.0   4.1e-51   7.3e-47      27     320 ..       1     344 [.       1     350 [. 0.81

  Alignments for each domain:
  == domain 1  score: 160.0 bits;  conditional E-value: 4.1e-51
                   HHHHHHHHHH.HHHHHHHHSTTTS-TT-EEEEEE--SS....TTSSEEEEEEESSSB-SSTHHHHHHHHHHHHH...TTSS-SE........EEECE CS
  Pro_racemase  27 aekrrlleedldalRralllePRGhdvmsgallvppke....pdadlgvifletsgylpmcGsntigvvtvlle...tGlvevq........epetk 108
                   +e+r+  +e++d+ Rr+l+lePRGh++m+ga+l p +e     +ad+g +f++++g ++mcG++ti++ ++l++   + + + +        +++t+
    EEA22649.1   1 MEQRAQAKEKFDQYRRFLMLEPRGHRDMYGAILRPETElvktGEADFGALFMHNDGFSTMCGHATIALGRFLVDcddEQIFPRRkllkynaeTQTTS 97 
                   6899999****************************864333389****************************9733233444336666667688899 PP

                   EEEEETTEEEEEEEEC....TSTSEEEEEEE-S-BEEEEEEEEEEETT......TE...EEEEEEEESSSEEEEEEGGGCTS..-SSCCCHHHHHHH CS
  Pro_racemase 109 lsletpaGlvevtaec....rdgkvervslenvpsfvyaldvevevpg......lG...kvkvDiayGGnfyaiveaeklgl..dlekaearelvea 190
                   ++l++p+G+v+v + +    +++    vs+ +vpsf+    v+v++p+      lG   ++++D  yGG++y ++ a++lg+   l++++ ++l +a
    EEA22649.1  98 IRLHVPCGVVDVSVPTlvigKSDPSRPVSFISVPSFATGISVTVHLPEenrwpeLGgrdSITADFCYGGAYYCVIGATELGFpqGLSEDDIQRLSHA 194
                   ***********9986533225557899*****************9875222222543446********************9733699********** PP

                   HHHHHHHHHHHH--....-TTCSTTC-SEEEEEEEEEETTTTS...EEEEEEEETTSEB-SS--HHHHHHHHHHHHHTTSS-TT-EEEEEET.TS-E CS
  Pro_racemase 191 geklrealneqlkv....qhpenedirevslveltgkkeraea...earnaviisdkkvDRSPcGtgtsArlAvlaakGklkvgeefvqesi.iGse 279
                   +  l++ +ne+ ++    +h+++ +   ++ v ++++++r ++   + + +++++++++DRSP+G  ++Ar+ + + kG l++ge+ +  s+ +Gs+
    EEA22649.1 195 TALLKKTVNENPDLssltRHIQTSEQGVLYSVLIVDDAKRINDpssSEKGLCFFANQQIDRSPTGGSVAARIGLAYTKGDLSIGEQRKFDSLfTGSN 291
                   **********9875333379999************999988776668899*************************************9998634554 PP

                   .....EEEEE.EEEEEECTCE......EEEEEEEE-EEEEEEEEEEE-TT-TT CS
  Pro_racemase 280 .....Fegrv.eeeaevggrk......aivpeisGrafitglaqllldpsDPf 320
                        F g++ ee+++ +g++      ++ +++ G a ++g+++++ + +D +
    EEA22649.1 292 kglkgFVGSAfEELKKESGVDgsqkniSVRVKVEGYANYMGYSTFVAEKADGL 344
                   34333554431333444444455678889999**************9999976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (351 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       325  (0.0181271); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.31s 00:00:00.81 Elapsed: 00:00:00.49
# Mc/sec: 2172.33
//
Query:       EEA22650.1  [L=613]
Description: carnitine acetyl transferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.6e-205  684.2   0.0   1.8e-205  684.1   0.0    1.0  1  Carn_acyltransf  Choline/Carnitine o-acyltransferase


Domain annotation for each model (and alignments):
>> Carn_acyltransf  Choline/Carnitine o-acyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  684.1   0.0  9.8e-210  1.8e-205       1     586 [.      31     596 ..      31     597 .. 0.94

  Alignments for each domain:
  == domain 1  score: 684.1 bits;  conditional E-value: 9.8e-210
                      S-------HHHHHHHHHHHHHCCSHHHHHHHHHHHHHHHHC..THHHHHHHHHHHHHSSHT-STTTHHHHHHHHTTT--S-HHHHTBEEEE-GC CS
  Carn_acyltransf   1 LprLPvPkLedTleryleslkpllseeelekteklveeflk..geGpkLqerLraekekktsknwledwWedyaYleyrdplvlnsnpfllled 92 
                      Lp+LPvP+Le+T++ryl+s++plls+ e+e+t k+v+ef +  g+G++Lq+rL+a++e+++ +nwl +wW+  aYl yrdp+v+++++f+  +d
       EEA22650.1  31 LPKLPVPTLEETARRYLKSVRPLLSAPEYERTTKVVQEFIRpgGQGETLQKRLIARREDPKINNWLIEWWNFGAYLGYRDPVVPYVSYFYSYKD 124
                      9*****************************************99*********8887777789***************************9998 PP

                      CCCTSTCHHHHHHHHHHHHHHHHHHHHHHTT-S--TE.EETEE---GGGGGSSSEEEE--SSS-EEEEE--TSS---EEEEEETTEEEEEECEC CS
  Carn_acyltransf  93 dpdpkeknqqlkraAklilsalkfkkllrreelepdvikkgkplcmsqykrlfnttRiPgkekDklvkykkedkesrhivVlrkgqfYkvdvle 186
                      d + +++n++ +raA+++lsal+fk+++++++lep+ ++ + p+ ms+y+++fn++RiP+ ++D+ +ky++e  e++hi+V+rk+qf+kv+ + 
       EEA22650.1 125 DRK-RRSNPA-ARAATVTLSALEFKRQVDDGSLEPEYLR-KIPMAMSSYQYMFNCSRIPALPADYPQKYSPE--ENQHITVVRKNQFFKVPYV- 212
                      888.888888.*************************774.79***************************884..6*****************9. PP

                      ECTTEE--HHHHHHHHHHHHHHHHCCG.----GGGGGGS-HHHHHHHHHHHCC-TCHHHHHHHHHHCSS-EEEE----SS---HCCHHHHHHCT CS
  Carn_acyltransf 187 ddggrllspaelekqleeIlsdsekeesaeepvgvlTtenRdewakareellksekkNkeslelIesalfvvcLDdespededeeelakqllhg 280
                       +g + l+  el+kq+e I++ + ++  +  pvgvlT++nRd+w+ +r++ll ++++N+++l+ Ies++f+vcLDd++p + +e  +a+q++hg
       EEA22650.1 213 VNG-QKLTCGELQKQFEVIYERA-EH--PVTPVGVLTAANRDHWTATRAKLLDASPANAKALKDIESSAFLVCLDDAAPVTLEE--RAHQYWHG 300
                      355.889*************433.33..69********************9988777*********************966666..******** PP

                      TCGC--TTBSEEEEE-TTS-EEEEE-STT--HHHHHHHHHHHHHCCHCTTTT--S----S-SSS....-EEE-----HHHHHHHHHHHHHHHHH CS
  Carn_acyltransf 281 sgtnRWfDKslqlivtknGkaglnfEHswaDgtvvlrlvedvltdsilkeakekneeksssseeslpepeklefkldeelkeaieeaetrldkl 374
                      +g nRW+DK+lq+i+++nG+ag+++EHs++Dgt++ rl+++v + +  ++ +     ++++ +++lp+p +++f+l+ el++ai+ea++++++l
       EEA22650.1 301 DGCNRWYDKPLQFIINDNGTAGFMGEHSMMDGTPTQRLNDYVNSLIFGNKLEY----DNTPVRSTLPPPAPINFELNVELEQAINEAHQEHKSL 390
                      999**************************************999995554443....33444444789************************** PP

                      HCCEEEEEEEETS--HHHHCCCT--HHHHHHHHHHHHHHHHHSS---EEEEEE-TTSTT--EEEEE---HHHHHHHHHHHS.SCTHCCHHHHHH CS
  Carn_acyltransf 375 isdldlkvlefkeyGksfikkfklspDafiQmalQlAyyrlygklaatyEsastrkFrhGRtEtirsvteeslafvkamds.kasdeeklellr 467
                      i+ ++l+v  f+ yGk++ikkfk+spDa++Qm +QlAyy++yg  ++tyEsastrkF++GRtE+ir+v+++s af++a ++ ++ +ee  +l+r
       EEA22650.1 391 IAAHELRVQAFQAYGKGLIKKFKCSPDAYVQMLIQLAYYKMYGINRPTYESASTRKFKEGRTEVIRTVSDDSTAFCRAHQDpNVPREEVVKLFR 484
                      ******************************************************************************96668899999***** PP

                      HHHHHHHHHHHHHHTTTSSHHHHHHHHHHHHHT--HHSS.-HHHHSHHHHHCT--SEEEEE...SSSEEEES--SSTT-EEEEEEEETC.EEEE CS
  Carn_acyltransf 468 kAvkahskltkeaakGkGvdrHLfaLkllakelesegeelpelFkdplykklnnwrLsTSqlsspalkgfGfgpvvpdGyGigYiikddsisfv 561
                      +A+k+h+k+t ea++GkGvdrHL++Lk l++    ege+lpe+F+dp+y ++++w+LsTSqlss++++g+G+++v++dG+Gi+Y+i++ds++f+
       EEA22650.1 485 EALKQHTKYTMEASDGKGVDRHLLGLKKLVQ----EGEKLPEIFEDPAYGYSSSWYLSTSQLSSEYFNGYGWSQVIDDGFGIAYMINEDSLQFN 574
                      ***************************9998....7899******************************************************* PP

                      EEETCTTS--HHHHHHHHHHHHHHH CS
  Carn_acyltransf 562 isskkksetsserfaeaLeealedi 586
                      + sk   +   er++ +L+ea+ ++
       EEA22650.1 575 VVSK---RLGCERLSFYLNEAALEV 596
                      ***6...569**********99987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (613 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       487  (0.0271627); expected 358.6 (0.02)
Passed bias filter:                      449  (0.0250432); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.30s 00:00:00.88 Elapsed: 00:00:00.44
# Mc/sec: 4182.11
//
Query:       EEA22651.1  [L=389]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
     0.0061   15.8   6.1      0.014   14.6   2.1    2.1  2  DUF2046        Uncharacterized conserved protein H4 (DUF2046)
     0.0094   14.6   4.5      0.017   13.8   4.5    1.4  1  DUF3138        Protein of unknown function (DUF3138)
  ------ inclusion threshold ------
       0.04   13.6   0.4       0.04   13.6   0.4    2.0  3  AAA_30         AAA domain
      0.076   12.8   0.1      0.076   12.8   0.1    2.4  2  DivIC          Septum formation initiator
       0.46   10.7   8.1       0.44   10.8   0.2    2.1  2  Jnk-SapK_ap_N  JNK_SAPK-associated protein-1
        0.7   10.5  12.4        7.6    7.2   0.1    2.6  2  SlyX           SlyX


Domain annotation for each model (and alignments):
>> DUF2046  Uncharacterized conserved protein H4 (DUF2046)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   2.1   4.7e-06     0.014     168     208 ..     165     207 ..     159     226 .. 0.67
   2 ?    2.9   0.1     0.018        53      14      54 ..     299     340 ..     287     354 .. 0.71

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 4.7e-06
     DUF2046 168 elentleqeqealvnrlWkrl..dkleaekrllqekldqpvsa 208
                 el + leqeqea vnrl + +  ++l+ ++  lq++  qp sa
  EEA22651.1 165 ELHQELEQEQEAQVNRLLQMIrqQQLQLQQLQLQQQQGQPSSA 207
                 6788888888888888877441145555555566666666555 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.018
     DUF2046  14 tllepssvkr.eelqkrveslqqenrvlkieldtyklrvkal 54 
                 ++++++s+      q +v+sl+++nr+l+  +     ++  l
  EEA22651.1 299 MAARRGSLDDsAYYQAQVDSLNRDNRMLRARIRVLERQITEL 340
                 444455554424568899999999999999887777776655 PP

>> DUF3138  Protein of unknown function (DUF3138)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.8   4.5   5.7e-06     0.017      19      85 ..     315     382 ..     296     388 .. 0.72

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 5.7e-06
     DUF3138  19 aaaatadrikalkaqltalqrqvkelraalaaakaaaGgkissqkaaaaa.aaaaeaaaalteddvaq 85 
                 ++++   + + l+a+++ l+rq++el ++  aa a a + +    +aa a +++a a+ a ++d+ + 
  EEA22651.1 315 QVDSLNRDNRMLRARIRVLERQITELSTSSSAAAAVAATSVEPTTTAAVAtGNSAGASGAAARDEPQA 382
                 344445556789******************99999999988877666655155566777777776655 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.4   1.3e-05      0.04     117     180 ..     147     208 ..     133     219 .. 0.89
   2 ?   -3.1   0.0       1.9   5.5e+03     147     175 ..     279     307 ..     273     325 .. 0.64
   3 ?   -2.3   1.0         1     3e+03      46      76 ..     334     363 ..     323     380 .. 0.59

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 1.3e-05
      AAA_30 117 akvilvGDerQlasVeaGgvlrdlveaagigtaeLtevvRqkeseeraaalalregdaeealea 180
                   +i  GD++   + + G++ ++l +++++++ +L +++Rq++ + +++ l+ ++g++++a   
  EEA22651.1 147 SPIIATGDPHHQRAPSLGELHQELEQEQEAQVNRLLQMIRQQQLQLQQLQLQQQQGQPSSA--V 208
                 56899*******************9999*****************************9966..3 PP

  == domain 2  score: -3.1 bits;  conditional E-value: 1.9
      AAA_30 147 gtaeLtevvRqkeseeraaalalregdae 175
                  +  L+++v  +++++++ + a r+g  +
  EEA22651.1 279 SVFDLNDLVDRDRERQQESSMAARRGSLD 307
                 55666666666667788888888888777 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 1
      AAA_30  46 ggrviglAptgkaAkvLaeelgieastiakl 76 
                 ++++  l+ ++ aA+++a+   +e  t+a +
  EEA22651.1 334 ERQITELSTSSSAAAAVAAT-SVEPTTTAAV 363
                 46677777777777777743.4433333333 PP

>> DivIC  Septum formation initiator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   8.2       4.6   1.4e+04      18      41 ..     177     200 ..     165     205 .. 0.67
   2 ?   12.8   0.1   2.6e-05     0.076      23      61 ..     313     351 ..     303     352 .. 0.89

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 4.6
                 HHHHHHHHHHHHHHHHHHHHHHHH CS
       DivIC  18 aykqlkqeiaalqaelaklkaene 41 
                 ++ +l q i ++q +l++l+ +++
  EEA22651.1 177 QVNRLLQMIRQQQLQLQQLQLQQQ 200
                 445556666666666666666665 PP

  == domain 2  score: 12.8 bits;  conditional E-value: 2.6e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHHCC-XXXXXXXXXXX CS
       DivIC  23 kqeiaalqaelaklkaeneeLeaevkdLksdedyieerA 61 
                 +++++ l++++  l+a+++ Le+++ +L+ + ++ +++A
  EEA22651.1 313 QAQVDSLNRDNRMLRARIRVLERQITELSTSSSAAAAVA 351
                 68**************************88877776665 PP

>> Jnk-SapK_ap_N  JNK_SAPK-associated protein-1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   3.1     0.046   1.4e+02      81     113 ..     168     200 ..     155     224 .. 0.68
   2 ?   10.8   0.2   0.00015      0.44      72     128 ..     290     346 ..     284     359 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.046
  Jnk-SapK_ap_N  81 eeiedqweeerkelqekveqleeenrelelkak 113
                    +e+e++ e + + l +++ q + + ++l+l+ +
     EEA22651.1 168 QELEQEQEAQVNRLLQMIRQQQLQLQQLQLQQQ 200
                    456777777777777777777777777773333 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00015
  Jnk-SapK_ap_N  72 lrkraeeeleeiedqweeerkelqekveqleeenrelelkaknaadqlsrleekeae 128
                    +r+r++e  + +     ++   +q++v +l+ +nr+l ++++ ++ q+++l+ +++ 
     EEA22651.1 290 DRERQQESSMAARRGSLDDSAYYQAQVDSLNRDNRMLRARIRVLERQITELSTSSSA 346
                    57778888888888888889999****************************998875 PP

>> SlyX  SlyX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   8.4     0.019        56      15      42 ..     174     201 ..     168     221 .. 0.88
   2 ?    7.2   0.1    0.0025       7.6      29      54 ..     312     337 ..     306     351 .. 0.80

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.019
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        SlyX  15 qedtieeLndvvaeqqqqidrlqrqlrl 42 
                 qe ++++L +++ +qq q+++lq q ++
  EEA22651.1 174 QEAQVNRLLQMIRQQQLQLQQLQLQQQQ 201
                 9999******************998765 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0025
                 HHHHHHHHHHHHHHHHHT-XXXXXXX CS
        SlyX  29 qqqqidrlqrqlrllaerlkeleess 54 
                  q q+d l r  r+l+ r++ le + 
  EEA22651.1 312 YQAQVDSLNRDNRMLRARIRVLERQI 337
                 58899999999999999998887764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (389 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1774  (0.0989458); expected 358.6 (0.02)
Passed bias filter:                      709  (0.0395449); expected 358.6 (0.02)
Passed Vit filter:                        90  (0.0050198); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.72u 0.34s 00:00:01.06 Elapsed: 00:00:00.52
# Mc/sec: 2255.92
//
Query:       EEA22652.1  [L=562]
Description: Lectin C-type domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0065   17.2   0.5       0.33   11.7   0.1    2.8  3  Lectin_C  Lectin C-type domain


Domain annotation for each model (and alignments):
>> Lectin_C  Lectin C-type domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.0         1   1.8e+04      39      49 ..      13      24 ..      12      30 .. 0.66
   2 !   11.7   0.1   1.8e-05      0.33      52     107 ..     366     422 ..     351     423 .. 0.86
   3 ?    2.6   0.0     0.012   2.2e+02       4      63 ..     438     500 ..     435     513 .. 0.66

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 1
                TSEEEEEE.EES CS
    Lectin_C 39 nkkfWigl.tde 49
                n++fW+ l +++
  EEA22652.1 13 NSTFWVNLlSQR 24
                5789**994333 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 1.8e-05
                 TTEEEETTSTBCSTTTC..TE-BSTSCSTTEEEEEEGSSTTSEEEEEETTSEEEEEEE CS
    Lectin_C  52 egewkwedgskltteql..yknwpsnnsenedCvelrekssgkwndesCnekkpfvCe 107
                 ++ w+w  +++ + ++l  ++ +  +n++   C+ l+ +s+g+w++ +C++ +++ C+
  EEA22652.1 366 SSMWSWAVDEPRNVSSLpgFEDL-GPNNDILRCAMLDPTSNGRWRAGNCSNAYRAACR 422
                 67899999999999988764444.67888899**********************9996 PP

  == domain 3  score: 2.6 bits;  conditional E-value: 0.012
                 EHHHHHHHHHHTTSEEB--SSHHHHHHHHHHCT......CTTSEEEEEEEESSSTTEEEETTSTBC CS
    Lectin_C   4 swqeAeeaCqkeggsLasvnskeelkflssllk......ksnkkfWigltdeksegewkwedgskl 63 
                 s++++ + C +  +s   +++  e+ +l +++        +n+ +Wi l  +  + +++w+ g  +
  EEA22652.1 438 SFSDSSNICPSG-SSFDIPRTGLENTYLYHTALssrdttTPNEPIWINL--NSIDVQYCWVMGGAN 500
                 556666666543.33333445556666655555566668899*******..888888888877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (562 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       319  (0.0177924); expected 358.6 (0.02)
Passed bias filter:                      281  (0.0156729); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.24s 00:00:00.77 Elapsed: 00:00:00.41
# Mc/sec: 4128.12
//
Query:       EEA22653.1  [L=393]
Description: translocation protein Sec62, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    7.8e-74  247.8   1.0    7.8e-74  247.8   1.0    1.6  2  Sec62        Translocation protein Sec62


Domain annotation for each model (and alignments):
>> Sec62  Translocation protein Sec62
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.3      0.16   2.9e+03      36      58 ..      29      51 ..      10      90 .. 0.51
   2 !  247.8   1.0   4.4e-78   7.8e-74       1     213 [.     144     349 ..     144     352 .. 0.94

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.16
       Sec62 36 kkekaekvfkelkksqlalrvek 58
                k+  + ++f +++++q+a++++k
  EEA22653.1 29 KRGMTPEAFVKMQREQVAAEAAK 51
                22223333333333333333333 PP

  == domain 2  score: 247.8 bits;  conditional E-value: 4.4e-78
       Sec62   1 kkkdffrakkvvralksekekkkskkkkeklkevkkkekaekvfkelkksqlalrveklkekekkkkkeekkkkkkkkkkvkleieeeqefvddnevYv 99 
                 ++kd+f++k+++ra +s++++k+++k+k  l++v+++++ae+vfk+l+ s lalrv+k++ +  +++     k+k+ k+ ++++ie++qe+ d+ ++Yv
  EEA22653.1 144 QRKDMFKVKRAIRAIESPAYAKAAAKSKGLLPPVTDRASAENVFKLLPLSLLALRVTKQDPHAGHNH----GKTKRVKGLWTVKIEQHQET-DPMMHYV 237
                 689********************************************************88888887....589*****************.******* PP

       Sec62 100 WiYepkqlktlligllvvvailavvlFPLWPaelrkgvyYLSiaalgllglilalaivRlilflivllvtkgklhlWlfPnlfeDvGfldSFrPlYeye 198
                  +Ye++q+k+++++++vv+ai+avvlFPLWP +lr+gv+YLS++++gllg+++a++i+Rlilf++++++++++  lWlfPnlfeDvGf+dSF+P+++++
  EEA22653.1 238 FLYEGSQWKQKAMAVGVVLAIFAVVLFPLWPIVLRQGVWYLSVGMMGLLGAFFAMSIFRLILFCVTVFAVPPG--LWLFPNLFEDVGFFDSFKPVWGWQ 334
                 *************************************************************************..************************ PP

       Sec62 199 ekdkkkkkkkkkkkk 213
                 ek+kkk k++kk+k+
  EEA22653.1 335 EKKKKKVKSAKKAKS 349
                 755555555555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (393 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1717  (0.0957666); expected 358.6 (0.02)
Passed bias filter:                      710  (0.0396006); expected 358.6 (0.02)
Passed Vit filter:                        70  (0.00390429); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.46
# Mc/sec: 2581.79
//
Query:       EEA22654.1  [L=465]
Description: phytase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.6e-65  222.0   0.0    1.8e-65  221.8   0.0    1.0  1  His_Phos_2  Histidine phosphatase superfamily (branch 2)


Domain annotation for each model (and alignments):
>> His_Phos_2  Histidine phosphatase superfamily (branch 2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  221.8   0.0     1e-69   1.8e-65       2     383 .]      71     425 ..      70     425 .. 0.97

  Alignments for each domain:
  == domain 1  score: 221.8 bits;  conditional E-value: 1e-69
                 EEEEEEEEE--SBB-SHHHHHHHHHHHHHHHH.........HHCHHTGCCGGGGT.........--SSSTTS.B-HHHHHHHHHHHHHHHHHCHTCCHT CS
  His_Phos_2   2 LksvvvviRHGdRtPkqkvkksvtspiflsllkkhkeKlkqlktalekkghfpgtyrkveveklqlilkwggelthaGrkqaeelGrqfrqrYplgLlr 100
                 +++v+++ RHG+R+P+ k++  ++++i +++          ++t+le+k++f++ty        ++   +   lt++G +++++ G++f+ rY+  L+r
  EEA22654.1  71 VTFVQSLTRHGARYPTAKKNTAYKKLIEAIQT---------NATKLEGKYAFLKTY--------NYSWPAAT-LTPFGTNELYQAGIKFYDRYE-SLAR 150
                 689*****************************.........8************99........99999999.*********************.**** PP

                 TSS--TTEEEEEESSHHHHHHHHHHHHHHCHCCC---S-TTSTTGGG-TTTTCCCEEEHHHHCCCCHHCTTSHHTCHHHCHHHTGGHCHHHHCHCCCCC CS
  His_Phos_2 101 lhltykdlkirassegRviaSAaafakGllglegeltdllskdkdllddsnaakdlldeakkklkelltegaeacpafewpikvakrvdelvkylkedm 199
                 +     ++++r s+++RviaS++af  G+   ++      ++  d ++  ++ +++l e   +++ ++t ++  c++fe+    +   d+ ++ +++++
  EEA22654.1 151 D----TVPFVRVSGSDRVIASGEAFNSGFQVTKN-----ADRFADKSQAAPVINVVLTE---SDTFNNTLDHGLCTNFEN----SDLADDIQAGFAATF 233
                 *....89***********************8888.....89999999999999999999...9*****************....*************** PP

                 HHHHHHHCHHHCTTEEEE-HHHHHHHHHHHHHHHH.....HHCT-TTGGGCTH..HCHHHHHHHHHHHHHHHC........TTTCCCCHHHHHHHHHHH CS
  His_Phos_2 200 deniakrleqlcpgesnllakerwdklercfyekn.....kfdiskicdlydemkydalhnrylkdleelyklakvipqEygigpeeklkiGllllnpl 293
                  ++i kr+++ ++g  +l+  ++  ++++c++++      ++++s++cdl+++  +++++++y+++l ++y++          g+++++++G+++ n+l
  EEA22654.1 234 VPKILKRVQAHLHGV-TLTTTNIIYLMDMCAFDTVartsdASELSPFCDLFTK--SEWEEYNYYQSLGKYYGY--------SAGNPLGPAQGIGFTNEL 321
                 **************8.*************************************..******************........****************** PP

                 HHHHCTSSSEECCS.........CCCECS-SEEEEEE-HHHHHHHHHHCTTTTTBTTB.SSS......TTT..HCCCS-CT-EEEEEEEEETCTTTEEE CS
  His_Phos_2 294 lkkilndlqrtree.........atperhvrlrlyfthdshiysllnaLglpeelagedslaa.....ldrlsaspelpymsqivfelyedssekkfyv 378
                 +++++  ++++ ++          t++ h++l+++f+hd    ++++a+gl++ + +++++++     ++r+sa++ +p+++++++el+ ++ ekk  v
  EEA22654.1 322 IARLTGTPVKDGTStnqtldsspVTFPLHATLYADFSHDDGTEPIFAAMGLFNGTSPLSETKVestkqTNRFSAAWTVPFAARMYVELMTCKGEKKPLV 420
                 ************99********************************************99999****************************99999*** PP

                 EEEEC CS
  His_Phos_2 379 rllls 383
                 r l++
  EEA22654.1 421 RALVN 425
                 *9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (465 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       421  (0.0234815); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 3152.77
//
Query:       EEA22655.1  [L=1047]
Description: peptidase family M20/M25/M40 protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
       0.04   14.4   0.0      0.094   13.2   0.0    1.7  1  PH        PH domain


Domain annotation for each model (and alignments):
>> PH  PH domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   5.3e-06     0.094      70     104 ..     340     375 ..     253     376 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 5.3e-06
                 EEEEESTSSS.TEEEEEEESSHHHHHHHHHHHHHHH CS
          PH  70 felriverng.srtyllqasseeerkeWikaiqsai 104
                 f l ++e+++  rt+l   ss++e+++W+ a++++i
  EEA22655.1 340 FGLHTSESRRsVRTFLVIMSSAQEMNSWLIAFRKMI 375
                 444777766666********************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1047 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       935  (0.0521501); expected 358.6 (0.02)
Passed bias filter:                      314  (0.0175135); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.95u 0.37s 00:00:01.31 Elapsed: 00:00:00.58
# Mc/sec: 5480.14
//
Query:       EEA22656.1  [L=531]
Description: NADPH-adrenodoxin reductase Arh1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.9e-09   35.8   0.0    2.2e-08   33.7   0.0    2.0  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
     0.0041   17.3   0.0     0.0089   16.2   0.0    1.5  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
  ------ inclusion threshold ------
      0.027   13.2   0.0      0.044   12.5   0.0    1.3  1  HI0933_like    HI0933-like protein
      0.076   12.1   0.0       0.85    8.6   0.0    2.1  2  FAD_binding_2  FAD binding domain
       0.12   12.4   0.0       0.29   11.1   0.0    1.7  2  NAD_binding_9  FAD-NAD(P)-binding
       0.13   12.7   0.0        8.5    6.9   0.1    2.3  2  NAD_binding_7  Putative NAD(P)-binding


Domain annotation for each model (and alignments):
>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.7   0.0   7.4e-12   2.2e-08       1     161 [.      38     197 ..      38     231 .. 0.65
   2 ?   -2.1   0.0      0.61   1.8e+03     226     266 ..     355     396 ..     335     400 .. 0.66

  Alignments for each domain:
  == domain 1  score: 33.7 bits;  conditional E-value: 7.4e-12
                  CSEEEE--SHHHHHHHHHHHHH..TS-EEEEETTHCHHHCSHHHHCHHHHHHHHHHHHHHHHHCHHHHCCCCHCCTCEEEEESCEEEEETEEECTCEE CS
                  xxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2   1 kdvvviGgGpAGlaaaltlaqa..gakvtlvelegtclnggcllskallgvaedaeiasevvkklnqgielllgeevvkidpgkkkvklekkkegdee 96 
                  ++v+viG+GpAG+ aa +l  +   a v ++  e+  + +g + + ++   +e ++         +++++ +++++ +++  g+   + +++   ++ 
   EEA22656.1  38 FRVAVIGSGPAGFYAAYRLLSKsdDAVVDMY--EQLPVPFGLVRYGVAPDHPEVKNC--------EEKFTEVATSPRFNF-IGN-VAVGSQLP-FSTL 122
                  58*****************995225555566..444444455655666666666553........334555555555666.444.22222222.4556 PP

                  EEEESEEEE---.EEE-BCTCTTC.........TTBEECCSECHHHHHHCCSS-T.SEEEEES-SHHHHHHHHHH CS
                  xxxxxxxxxxxx.xxxxxxxxxxx........xxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  97 kiaydklvlAtG.ssprdlgipGv........aenvgklvrtldsaealklkllp.krivvvGgGyiGvElAaal 161
                  k  yd+++ A G ++ r lgipG+        a   +     l + + l  +l   +++vvvG G++++++A  l
   EEA22656.1 123 KPHYDAILFAYGaAKDRELGIPGEdarknvlsARAFVGWYNGLPEYRDLAPDLAAgEHAVVVGQGNVALDVARIL 197
                  789*********559999******66555555333333334555555555555549****************985 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.61
                  EEESEEEE-S-EEES-HHCS.HCCT-EEEETTEE.E--TTSBE CS
                  xxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxx.xxxxxxxx RF
  Pyr_redox_2 226 idadlvvvavGvrpstelle.eklglelderggi.vvdeflrt 266
                  i+    + ++G++  +   + e+lg+e d r+gi   d f+r+
   EEA22656.1 355 IPGNIFFRSIGYKSLPLP-GfEELGIEFDGRRGIiPNDGFGRV 396
                  666677778888877633.569999999766665155555555 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0     3e-06    0.0089       1      36 [.      42      79 ..      42      92 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 3e-06
                   EE--SHHHHHHHHHH.HCC.TEEEEEE-SSSSSSGGG- CS
  NAD_binding_8  1 IvGaGlsGlvaAylL.aka.gfdvlllekrdrlGGraa 36
                   ++G+G +G +aAy+L +k  ++ v+ +e+ + + G ++
     EEA22656.1 42 VIGSGPAGFYAAYRLlSKSdDAVVDMYEQLPVPFGLVR 79
                   8************9625646999*****9999888665 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   1.5e-05     0.044       2      26 ..      39      65 ..      38      73 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.5e-05
                 SEEEE--SHHHHHHHHHH..HHTT--E CS
  HI0933_like  2 dviviGgGaAGlmaAisa..akrgkrV 26
                 +v+viG G+AG++aA ++  ++ ++ V
   EEA22656.1 39 RVAVIGSGPAGFYAAYRLlsKSDDAVV 65
                 79**************99533333334 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.0   0.00028      0.85       2      21 ..      40      59 ..      39      70 .. 0.84
   2 ?    1.0   0.0     0.058   1.7e+02     388     402 ..     414     428 ..     399     436 .. 0.79

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00028
                   EEEE--SHHHHHHHHHHHHT CS
  FAD_binding_2  2 viViGsGlAGLaAAleaaea 21
                   v ViGsG AG  AA+++  +
     EEA22656.1 40 VAVIGSGPAGFYAAYRLLSK 59
                   89*************98665 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.058
                    EEESSBTEEE-STCE CS
  FAD_binding_2 388 dgqpipGLYAaGeva 402
                    + +++pGLY+aG v 
     EEA22656.1 414 HISHLPGLYCAGWVK 428
                    55799*******775 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   9.6e-05      0.29       1      33 [.      41      70 ..      41     107 .. 0.84
   2 ?   -2.9   0.0         2     6e+03       1      25 [.     182     206 ..     182     210 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 9.6e-05
  NAD_binding_9  1 aivGaGprGlavlerLlarakkkspleitlfdp 33
                   a++G Gp+G +++ rLl+++   ++  ++++++
     EEA22656.1 41 AVIGSGPAGFYAAYRLLSKS---DDAVVDMYEQ 70
                   89*****************5...7777888777 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 2
  NAD_binding_9   1 aivGaGprGlavlerLlarakkksp 25 
                    ++vG G  +l v++ Ll+  ++ ++
     EEA22656.1 182 VVVGQGNVALDVARILLSDVDSLRK 206
                    699*********9999998755555 PP

>> NAD_binding_7  Putative NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0     0.034     1e+02       8      35 ..      38      65 ..      32     132 .. 0.79
   2 ?    6.9   0.1    0.0029       8.5       7      28 ..     178     199 ..     175     242 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.034
  NAD_binding_7  8 kkvlvvGgGevAarkvrklleagakvtv 35
                    +v v+G G+ +   +++ll+++ + +v
     EEA22656.1 38 FRVAVIGSGPAGFYAAYRLLSKSDDAVV 65
                   689*****************99877776 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.0029
  NAD_binding_7   7 gkkvlvvGgGevAarkvrklle 28 
                    g++ +vvG G+vA+  +r ll+
     EEA22656.1 178 GEHAVVVGQGNVALDVARILLS 199
                    799**********998888876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (531 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       433  (0.0241508); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.48
# Mc/sec: 3309.45
//
Query:       EEA22657.1  [L=694]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (694 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       753  (0.041999); expected 358.6 (0.02)
Passed bias filter:                      425  (0.0237046); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.64u 0.28s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 4595.14
//
Query:       EEA22658.1  [L=955]
Description: DUF726 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.8e-116  388.8   2.8   2.5e-116  388.3   2.8    1.1  1  DUF726         Protein of unknown function (DUF726)
    2.3e-06   27.8   0.3    1.2e-05   25.6   0.0    2.5  2  Glu-tRNAGln    Glu-tRNAGln amidotransferase C subunit
  ------ inclusion threshold ------
      0.018   15.1   0.3      0.098   12.7   0.0    2.3  2  Thioesterase   Thioesterase domain
      0.025   14.1   0.0      0.046   13.2   0.0    1.3  1  DUF900         Alpha/beta hydrolase of unknown function (DUF9
       0.13   12.8   1.0        1.3    9.6   0.0    2.4  2  Abhydrolase_6  Alpha/beta hydrolase family


Domain annotation for each model (and alignments):
>> DUF726  Protein of unknown function (DUF726)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  388.3   2.8  7.1e-120  2.5e-116       4     343 .]     462     813 ..     459     813 .. 0.97

  Alignments for each domain:
  == domain 1  score: 388.3 bits;  conditional E-value: 7.1e-120
      DUF726   4 krylliglAglaGgaligltggLaaPlvaagigallaglGltgsaa..fLasvggsa.vitallgaagAklsvkkmkkrvkeikdFefiplseqirl.. 97 
                 ++  ++glA++aG+alig+tggLaaPlvaag+g++++glGl+g+ a  +L++++ s  v++ l+ga+g k++++ m++   e++dF+fip+++ + +  
  EEA22658.1 462 RK-WKVGLATVAGAALIGITGGLAAPLVAAGLGTVMGGLGLGGTIAasYLGALASSGvVVGGLFGAYGGKMTGRMMDSYAREVEDFAFIPIRGTTAKkf 559
                 55.899*********************************998876666*****9999899*********************************998899 PP

      DUF726  98 ..........ksltvtvsislelsdeddvtapwralakaekdlYalkwEvelLkelGkaletilasealsvakqeilkrtvlaslvaaltWPlaLlkva 186
                           ++l+vt+ i +++++ed++t+pwr + +  ++++al+wE e+L +lG+++  +++++a++va q+ l  tv+a++++a+  P +L+++a
  EEA22658.1 560 kdekeaakedHRLRVTIGITGWVTEEDNITEPWRVIGPE-SEVFALRWEYESLLNLGNSMRALVTTAAWKVASQQLLIWTVFAGIMSAVMLPFGLMRIA 657
                 *********999**************************9.*********************************************************** PP

      DUF726 187 kildnpwnvsleraakaGklLAdallsraqGeRpvtLiGfslGARviyvCLlelakkkalglvenvillGaPvtteakvwlkvrsvvsgRlvnvysenD 285
                 ki  np++v+++ra+kaG++LAdal++ aqG+RpvtLiG+slG Rviy+CL+ lak++a+gl+e v+++GaP+++++ +w  +r+vv+gRlvnvyse+D
  EEA22658.1 658 KIAANPFSVAISRADKAGEVLADALINGAQGKRPVTLIGYSLGSRVIYSCLQSLAKRRAYGLIESVVFMGAPIPADSAKWHSMRAVVAGRLVNVYSEKD 756
                 *************************************************************************************************** PP

      DUF726 286 ylLgflyRtssaqfrvaglqrieldvekvenvdvselvegHldYrkklkkilkaigle 343
                  +L++lyR++  ++ + glq+++ +v+++en+dvs+ v+gHl+Y+ ++ ++l  ig+e
  EEA22658.1 757 AVLALLYRATHLEVDISGLQPVS-GVPNLENIDVSATVSGHLRYQFLVGQVLTDIGFE 813
                 ***********************.7******************************986 PP

>> Glu-tRNAGln  Glu-tRNAGln amidotransferase C subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.0   3.2e-09   1.2e-05       2      62 .]      87     194 ..      86     194 .. 0.74
   2 ?   -3.8   0.0       4.7   1.7e+04      10      23 ..     258     271 ..     256     271 .. 0.79

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 3.2e-09
                  -HHHHHHHHHHHHHHHHHHTTCGCS--TT----S..........-EB-S--............................................HHH CS
  Glu-tRNAGln   2 seeEleklakelnsildyveqLqevdttgveplthp........vlReDev............................................ree 47 
                  +  E+ +++++l++++++v+ +q+vdt +  pl+++              +                                            + +
   EEA22658.1  87 DKTEETSMLRTLEAQIHFVKSIQDVDTKDASPLRAIrvesreaiK-----EstisletlkealakeqvvgrrrkiqrqtttiedgkashvesdqwDGN 179
                  56799*******************************986555440.....144455555555555556677666677777777777788886665555 PP

                  HHTT-SSEETTEEEE CS
  Glu-tRNAGln  48 lLknApetedgyfvV 62 
                  +L  A +t++++fvV
   EEA22658.1 180 ALGSATKTAGKFFVV 194
                  699999999999988 PP

  == domain 2  score: -3.8 bits;  conditional E-value: 4.7
                  HHHHHHHHHHHTTC CS
  Glu-tRNAGln  10 akelnsildyveqL 23 
                   + l+ il+ +e+L
   EEA22658.1 258 EQMLSTILESFEAL 271
                  56689999999987 PP

>> Thioesterase  Thioesterase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.1      0.66   2.4e+03      96     169 ..      76     155 ..      73     195 .. 0.60
   2 ?   12.7   0.0   2.7e-05     0.098      59     118 ..     683     743 ..     672     773 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.66
                   EEEEESCCCCCCHHCHHCCCHTTHHT...HHHHHCCTTHH....HCCTTTHCCHHHHHHHHHHHHHHHHHTCCS....-TTSCSE CS
  Thioesterase  96 slflidssapseteaqeasrraedee...fveeltdlggt....epeelledeellsellpalradyraleqys....lrpeaaq 169
                    l l++ + p+  + +e s+  ++e+   fv+ ++d+       + ++  e+ e+ +e++  l   + al + +         ++
    EEA22658.1  76 LLRLSALPQPVD-KTEETSMLRTLEAqihFVKSIQDVDTKdaspLRAIRVESREAIKESTISLETLKEALAKEQvvgrR----RK 155
                   566888888988.555555555555559966666666544443666666777778888777777777777777744333....33 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 2.7e-05
                   HHHH-SSSSEEEEEETHHHHHHHHHHHHHHHC..T-SEEEEEEESCCCCCCHHCHHCCCHTT CS
  Thioesterase  59 lrqiqpegPyalfGhSlGgllAfevArqLesq..Glavkslflidssapseteaqeasrrae 118
                   ++  q + P++l+G+SlG+ + +   + L ++     + s+++ +++ p   +a++ s+ra 
    EEA22658.1 683 INGAQGKRPVTLIGYSLGSRVIYSCLQSLAKRraYGLIESVVFMGAPIPAD-SAKWHSMRAV 743
                   45566677*****************999999988556899999******98.***9999875 PP

>> DUF900  Alpha/beta hydrolase of unknown function (DUF900)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.0   1.3e-05     0.046      88     170 ..     684     761 ..     666     773 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.3e-05
      DUF900  88 atkksakkihllaHSmGtwlvlealrqlaieadepaveakikeviLaAPDidvdvfkkqleslgkeskeltvyvsrdDraLkl 170
                 + +++++ ++l+  S G++++ + l++la++         i+ v+++ + i +d +k ++++    ++ + vy s++D +L+l
  EEA22658.1 684 NGAQGKRPVTLIGYSLGSRVIYSCLQSLAKRRA----YGLIESVVFMGAPIPADSAKWHSMRAVVAGRLVNVY-SEKDAVLAL 761
                 45577889*********************9986....4799999999999*******9999999999999987.788988875 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.3      0.14   5.2e+02      64     104 ..     491     528 ..     464     647 .. 0.49
   2 ?    9.6   0.0   0.00035       1.3      56     117 ..     678     745 ..     659     844 .. 0.69

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.14
                    TTSEEEEEETCHHHHHHHHHHCC..EEEEES-..----TTT CS
  Abhydrolase_6  64 ggpvvlvGHSlGGalalaaaplalvvgvlldppptalpagl 104
                    g   v  G  lGG++a+ ++ ++  +gv++ +    ++a  
     EEA22658.1 491 GLGTVMGGLGLGGTIAASYLGALASSGVVVGG---LFGAYG 528
                    33458889999999999944444444566666...222222 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00035
                    HHCCTT.....TTSEEEEEETCHHHHHHH.HHHCC........EE.EEES-..----TTTS----TTHHHHHH CS
  Abhydrolase_6  56 lldelaa...gggpvvlvGHSlGGalala.aapla......lvvg.vlldppptalpagllaaalelllalla 117
                    l+d+l++   g +pv l+G+SlG  +    +++la      l+++ v++ +p +a+ a +       ++a+ a
     EEA22658.1 678 LADALINgaqGKRPVTLIGYSLGSRVIYScLQSLAkrraygLIESvVFMGAPIPADSAKW-----HSMRAVVA 745
                    334444466588999********9855554444444444666666788888333333333.....33333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (955 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       949  (0.052931); expected 358.6 (0.02)
Passed bias filter:                      496  (0.0276647); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.72u 0.30s 00:00:01.02 Elapsed: 00:00:00.44
# Mc/sec: 6450.81
//
Query:       EEA22659.1  [L=291]
Description: vesicular-fusion protein sec17 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     4e-115  384.1  13.0   4.5e-115  383.9  13.0    1.0  1  SNAP      Soluble NSF attachment protein, SNAP
    3.5e-07   30.4  10.5    0.00058   20.1   0.8    3.5  3  TPR_12    Tetratricopeptide repeat
       0.01   15.8  10.2        6.6    7.0   1.0    5.2  5  TPR_7     Tetratricopeptide repeat
  ------ inclusion threshold ------
       0.55   10.6  17.0       0.31   11.4   1.1    4.6  4  TPR_8     Tetratricopeptide repeat
        1.5    8.8  19.1       0.94    9.4   0.2    5.8  7  TPR_1     Tetratricopeptide repeat
        1.7    8.9  20.4        2.4    8.5   0.3    6.6  7  TPR_2     Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> SNAP  Soluble NSF attachment protein, SNAP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  383.9  13.0  1.5e-118  4.5e-115       2     282 .]       3     284 ..       2     284 .. 0.99

  Alignments for each domain:
  == domain 1  score: 383.9 bits;  conditional E-value: 1.5e-118
                 -HHHHHHHHHHHSS---THHHHH--SHHHHHHHHHHHHHHHHHHHHTT-THHHHHHHHHHHHHHHH.TT-HHHHHHHHHHHHHHHHHT-HHHHHHHHHH CS
        SNAP   2 kaeellakAekklksssglfslfgsksskaeeAadlyeqAAnayklakkweeAgeaflkaAecqek.lkekdeaanayveAakcykkvspeeAvealek 99 
                 ++++ll+kA+k+l+++s  fs+fg++s+k+e+Aadly+qAAna++++k+++eAg af+kaA++q++ l+e+d+aan++ eA+k+y+k++pe+Av++l  
  EEA22659.1   3 DPRALLQKADKALSGASTGFSFFGGRSEKYENAADLYVQAANAFRVQKMNKEAGMAFEKAAAVQRNnLNEPDDAANSLSEAFKVYRKTDPEDAVRVLAG 101
                 6789************************************************************999******************************** PP

                 HHHHHHHTT-HHHHHHHHHHHHHHHHHTT--HHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHTTSS-TTTGGGHHHH CS
        SNAP 100 AieiytekgrfrraAklkkeiaelyekelgdlekAieaYekAaelyeqeeakalankcllkvAelsaelekyekAieiyekvakkslennllkysvkey 198
                 Ai++y++kg+frraA++++++ae+ye e+g+ +kA+e YekAae+ye+++a+alank +lkvA+l+a +++y kAi  yekv+k s++nnl+k+svk+y
  EEA22659.1 102 AIQHYINKGNFRRAATHQQNLAECYEVEIGNAKKALEEYEKAAEWYESDNAEALANKYYLKVADLAAIEADYYKAIGYYEKVGKVSIDNNLMKWSVKDY 200
                 *************************************************************************************************** PP

                 HHHHHHHHHHTT-HHHHHHHHHGGG-----------HHHHHHHHHHHHTT-TTTHHHHHHHHTTSS---HHHHHHHHHHHHHHH CS
        SNAP 199 flkaglcrLaagDvvaakralekyeeldpsFassrEakllkdlleaveegdvekfteavkefDkiskldkWkttlLlkiKksie 282
                 f+kag+c+La+gD+va++rale y++ldp+Fas+rE+ ll dll+ave+g++++f++++++fD++skldkWkttl+l++K +ie
  EEA22659.1 201 FFKAGICHLASGDLVATNRALEGYRDLDPTFASTREHALLVDLLQAVEQGEPDTFADKLFQFDQLSKLDKWKTTLFLRVKGNIE 284
                 ********************************************************************************9986 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.2   2.3e-06     0.007       3      75 ..      36     106 ..      34     108 .. 0.87
   2 !   20.1   0.8     2e-07   0.00058      16      77 .]      89     149 ..      86     149 .. 0.88
   3 ?    2.7   0.3     0.053   1.6e+02       6      28 ..     159     182 ..     152     183 .. 0.80

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 2.3e-06
      TPR_12   3 atalnnlaavlrrlgrydeAlellekaleiarrllGpdhpltattlrnLgrlyralgryeeAlelleealaia 75 
                 a ++++ a++ r ++   eA   +eka +++r+ l++   ++a++l     +yr++ ++e+A++ l  a++ +
  EEA22659.1  36 ADLYVQAANAFRVQKMNKEAGMAFEKAAAVQRNNLNEPD-DAANSLSEAFKVYRKT-DPEDAVRVLAGAIQHY 106
                 7789999************************77755444.59***********999.******9998888776 PP

  == domain 2  score: 20.1 bits;  conditional E-value: 2e-07
      TPR_12  16 lgrydeAlellekaleiarrllGpdhpltattlrnLgrlyr.algryeeAlelleealaiaek 77 
                   + ++A + l  a++ + +  G  +  +at ++nL+++y+ + g+ ++Ale +e+a + +e+
  EEA22659.1  89 KTDPEDAVRVLAGAIQHYINK-GNFR-RAATHQQNLAECYEvEIGNAKKALEEYEKAAEWYES 149
                 5688999999999*****888.5555.89***********66*****************9985 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.053
      TPR_12   6 ln.nlaavlrrlgrydeAlellek 28 
                 ++ ++a++ +   +y +A+ ++ek
  EEA22659.1 159 YYlKVADLAAIEADYYKAIGYYEK 182
                 45258999999999*******998 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.1      0.01        31      12      29 ..      29      47 ..      28      55 .. 0.83
   2 ?   -2.1   0.0       1.8   5.2e+03      12      22 ..      70      80 ..      61      96 .. 0.70
   3 ?    1.1   0.0      0.17   5.1e+02      11      20 ..     108     117 ..     104     130 .. 0.53
   4 !    7.0   1.0    0.0022       6.6       5      24 ..     130     149 ..     121     159 .. 0.82
   5 ?    4.7   0.0     0.012        36      14      29 ..     172     185 ..     166     191 .. 0.80

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.01
       TPR_7 12 lGdyeeAielyeqsL.alt 29
                  +ye+A++ly q+  a++
  EEA22659.1 29 SEKYENAADLYVQAAnAFR 47
                568**********877766 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.8
       TPR_7 12 lGdyeeAiely 22
                l++ ++A+  +
  EEA22659.1 70 LNEPDDAANSL 80
                78888887654 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.17
       TPR_7  11 rlGdyeeAie 20 
                 + G++++A++
  EEA22659.1 108 NKGNFRRAAT 117
                 4455555544 PP

  == domain 4  score: 7.0 bits;  conditional E-value: 0.0022
       TPR_7   5 LarlysrlGdyeeAielyeq 24 
                 ++++  +l +ye+A+e ye 
  EEA22659.1 130 IGNAKKALEEYEKAAEWYES 149
                 6778888999*******996 PP

  == domain 5  score: 4.7 bits;  conditional E-value: 0.012
       TPR_7  14 dyeeAielyeqsLalt 29 
                 dy +Ai++ye+  +  
  EEA22659.1 172 DYYKAIGYYEK--VGK 185
                 7889******9..665 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.1     0.018        55       1      33 [.      36      68 ..      36      69 .. 0.89
   2 ?   -2.3   0.0       2.4   7.2e+03      11      20 ..     106     115 ..     106     117 .. 0.83
   3 ?   11.4   1.1    0.0001      0.31       5      33 ..     120     149 ..     119     150 .. 0.89
   4 ?    2.7   1.8     0.061   1.8e+02       3      27 ..     159     183 ..     158     186 .. 0.89

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.018
                CCHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8  1 aeayynlgsiylklgdyeeAkeyyekaleldpd 33
                a++y++ +++ + ++  +eA  ++eka   +++
  EEA22659.1 36 ADLYVQAANAFRVQKMNKEAGMAFEKAAAVQRN 68
                67899999999999*************988877 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 2.4
                 HHHTT-HHHH CS
       TPR_8  11 ylklgdyeeA 20 
                 y+++g++  A
  EEA22659.1 106 YINKGNFRRA 115
                 8999999877 PP

  == domain 3  score: 11.4 bits;  conditional E-value: 0.0001
                 HHHHHHH.HHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8   5 ynlgsiy.lklgdyeeAkeyyekaleldpd 33 
                 +nl+ +y  + g+ ++A e yeka e+ ++
  EEA22659.1 120 QNLAECYeVEIGNAKKALEEYEKAAEWYES 149
                 589999999***************999775 PP

  == domain 4  score: 2.7 bits;  conditional E-value: 0.061
                 HHHHHHHHHHHTT-HHHHHHHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAkeyyeka 27 
                 +y++ +++     dy +A+ yyek+
  EEA22659.1 159 YYLKVADLAAIEADYYKAIGYYEKV 183
                 7889999999999*********996 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.2      0.14   4.3e+02      15      27 ..      30      42 ..      28      43 .. 0.89
   2 ?    5.8   0.4    0.0045        13       1      34 []      36      69 ..      36      69 .. 0.90
   3 ?   -0.3   0.0      0.37   1.1e+03      13      31 ..      69      87 ..      68      89 .. 0.82
   4 ?   -1.9   0.0       1.2   3.5e+03      11      20 ..     106     115 ..     102     118 .. 0.64
   5 ?   -3.2   0.0       3.1   9.2e+03       6      11 ..     121     126 ..     120     127 .. 0.77
   6 ?    9.4   0.2   0.00031      0.94       7      25 ..     130     148 ..     128     149 .. 0.93
   7 ?    2.7   0.8      0.04   1.2e+02      16      27 ..     172     183 ..     166     183 .. 0.91

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.14
                T-HHHHHHHHHHH CS
       TPR_1 15 gkydeAleyyekA 27
                +ky+ A + y +A
  EEA22659.1 30 EKYENAADLYVQA 42
                69********988 PP

  == domain 2  score: 5.8 bits;  conditional E-value: 0.0045
                HHHHHHHHHHHHHTT-HHHHHHHHHHHHHHSTTH CS
       TPR_1  1 akalynlGnayfklgkydeAleyyekALelnPnn 34
                a+ + + +na++ +++ +eA  ++ekA  ++ nn
  EEA22659.1 36 ADLYVQAANAFRVQKMNKEAGMAFEKAAAVQRNN 69
                67788889*******************9999887 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.37
                HTT-HHHHHHHHHHHHHHS CS
       TPR_1 13 klgkydeAleyyekALeln 31
                +l+++d+A    ++A +++
  EEA22659.1 69 NLNEPDDAANSLSEAFKVY 87
                68999***99999998765 PP

  == domain 4  score: -1.9 bits;  conditional E-value: 1.2
                 HHHTT-HHHH CS
       TPR_1  11 yfklgkydeA 20 
                 y ++g++  A
  EEA22659.1 106 YINKGNFRRA 115
                 5566666665 PP

  == domain 5  score: -3.2 bits;  conditional E-value: 3.1
                 HHHHHH CS
       TPR_1   6 nlGnay 11 
                 nl+ +y
  EEA22659.1 121 NLAECY 126
                 788888 PP

  == domain 6  score: 9.4 bits;  conditional E-value: 0.00031
                 HHHHHHHTT-HHHHHHHHH CS
       TPR_1   7 lGnayfklgkydeAleyye 25 
                 +Gna   l++y++A e ye
  EEA22659.1 130 IGNAKKALEEYEKAAEWYE 148
                 79****************8 PP

  == domain 7  score: 2.7 bits;  conditional E-value: 0.04
                 -HHHHHHHHHHH CS
       TPR_1  16 kydeAleyyekA 27 
                 +y +A+ yyek+
  EEA22659.1 172 DYYKAIGYYEKV 183
                 899*******95 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.3       0.1   3.1e+02      14      28 ..      29      43 ..      28      47 .. 0.84
   2 ?    2.3   0.3     0.077   2.3e+02       1      34 []      36      69 ..      36      69 .. 0.86
   3 ?    0.5   0.0      0.29   8.5e+02      14      31 ..      70      87 ..      69      90 .. 0.81
   4 ?    2.4   0.1     0.071   2.1e+02      11      27 ..     106     122 ..     104     127 .. 0.79
   5 ?    8.5   0.3    0.0008       2.4      15      31 ..     131     147 ..     128     150 .. 0.56
   6 ?    3.2   0.8      0.04   1.2e+02       3      27 ..     159     183 ..     156     188 .. 0.81
   7 ?   -0.5   0.0      0.63   1.9e+03       3      17 ..     200     214 ..     199     215 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.1
       TPR_2 14 lgdyeeAleafekAl 28
                + +ye A++++ +A 
  EEA22659.1 29 SEKYENAADLYVQAA 43
                579********9996 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.077
       TPR_2  1 aealynlGlayyklgdyeeAleafekAleldPnn 34
                a+++ + ++a + ++  +eA  afekA +   nn
  EEA22659.1 36 ADLYVQAANAFRVQKMNKEAGMAFEKAAAVQRNN 69
                67888999999999999999999***99887776 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.29
       TPR_2 14 lgdyeeAleafekAleld 31
                l+++++A++ + +A + +
  EEA22659.1 70 LNEPDDAANSLSEAFKVY 87
                788999999999998765 PP

  == domain 4  score: 2.4 bits;  conditional E-value: 0.071
       TPR_2  11 yyklgdyeeAleafekA 27 
                 y+++g++ +A+ + +  
  EEA22659.1 106 YINKGNFRRAATHQQNL 122
                 9999******9987765 PP

  == domain 5  score: 8.5 bits;  conditional E-value: 0.0008
       TPR_2  15 gdyeeAleafekAleld 31 
                 g+ ++Ale +ekA e +
  EEA22659.1 131 GNAKKALEEYEKAAEWY 147
                 45556666666665544 PP

  == domain 6  score: 3.2 bits;  conditional E-value: 0.04
       TPR_2   3 alynlGlayyklgdyeeAleafekA 27 
                 ++   +++++   dy +A+ ++ek+
  EEA22659.1 159 YYLKVADLAAIEADYYKAIGYYEKV 183
                 56666777777889*********96 PP

  == domain 7  score: -0.5 bits;  conditional E-value: 0.63
       TPR_2   3 alynlGlayyklgdy 17 
                 + +  G +++++gd+
  EEA22659.1 200 YFFKAGICHLASGDL 214
                 67899*******996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (291 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       780  (0.0435049); expected 358.6 (0.02)
Passed bias filter:                      430  (0.0239835); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.53u 0.25s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 1911.05
//
Query:       EEA22660.1  [L=241]
Description: vesicular-fusion protein sec17 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.5e-94  314.1   9.7    9.5e-94  314.0   9.7    1.0  1  SNAP      Soluble NSF attachment protein, SNAP
    3.2e-06   27.3   7.5    0.00059   20.1   1.1    3.5  3  TPR_12    Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.043   13.9   6.7        5.8    7.2   1.2    4.4  5  TPR_7     Tetratricopeptide repeat
       0.44   10.8  15.4        1.9    8.8   0.3    5.8  6  TPR_2     Tetratricopeptide repeat
        1.1    9.2  12.5       0.74    9.7   0.2    4.9  6  TPR_1     Tetratricopeptide repeat
        2.6    8.5  15.9       0.24   11.7   1.1    4.3  5  TPR_8     Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> SNAP  Soluble NSF attachment protein, SNAP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  314.0   9.7   3.2e-97   9.5e-94      51     282 .]       2     234 ..       1     234 [. 0.99

  Alignments for each domain:
  == domain 1  score: 314.0 bits;  conditional E-value: 3.2e-97
                 THHHHHHHHHHHHHHHH.TT-HHHHHHHHHHHHHHHHHT-HHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHTT--HHHHHHHHHHHHHHHHHT CS
        SNAP  51 weeAgeaflkaAecqek.lkekdeaanayveAakcykkvspeeAvealekAieiytekgrfrraAklkkeiaelyekelgdlekAieaYekAaelyeqe 148
                 ++eAg af+kaA++q++ l+e+d+aan++ eA+k+y+k++pe+Av++l  Ai++y++kg+frraA++++++ae+ye e+g+ +kA+e YekAae+ye++
  EEA22660.1   2 NKEAGMAFEKAAAVQRNnLNEPDDAANSLSEAFKVYRKTDPEDAVRVLAGAIQHYINKGNFRRAATHQQNLAECYEVEIGNAKKALEEYEKAAEWYESD 100
                 79*************999********************************************************************************* PP

                 T-HHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHTTSS-TTTGGGHHHHHHHHHHHHHHTT-HHHHHHHHHGGG-----------HHHHHHHHHHHHT CS
        SNAP 149 eakalankcllkvAelsaelekyekAieiyekvakkslennllkysvkeyflkaglcrLaagDvvaakralekyeeldpsFassrEakllkdlleavee 247
                 +a+alank +lkvA+l+a +++y kAi  yekv+k s++nnl+k+svk+yf+kag+c+La+gD+va++rale y++ldp+Fas+rE+ ll dll+ave+
  EEA22660.1 101 NAEALANKYYLKVADLAAIEADYYKAIGYYEKVGKVSIDNNLMKWSVKDYFFKAGICHLASGDLVATNRALEGYRDLDPTFASTREHALLVDLLQAVEQ 199
                 *************************************************************************************************** PP

                 T-TTTHHHHHHHHTTSS---HHHHHHHHHHHHHHH CS
        SNAP 248 gdvekfteavkefDkiskldkWkttlLlkiKksie 282
                 g++++f++++++fD++skldkWkttl+l++K +ie
  EEA22660.1 200 GEPDTFADKLFQFDQLSKLDKWKTTLFLRVKGNIE 234
                 *******************************9986 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.0   0.0   0.00028      0.84      20      75 ..       3      56 ..       2      58 .. 0.84
   2 !   20.1   1.1     2e-07   0.00059      17      77 .]      40      99 ..      37      99 .. 0.88
   3 ?    3.3   0.2     0.034     1e+02       6      29 ..     109     133 ..     100     137 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00028
      TPR_12 20 deAlellekaleiarrl.lGpdhpltattlrnLgrlyralgryeeAlelleealaia 75
                 eA   +eka +++r+   +pd  ++a++l     +yr++ ++e+A++ l  a++ +
  EEA22660.1  3 KEAGMAFEKAAAVQRNNlNEPD--DAANSLSEAFKVYRKT-DPEDAVRVLAGAIQHY 56
                59999*********77725555..59***********999.******9998888776 PP

  == domain 2  score: 20.1 bits;  conditional E-value: 2e-07
      TPR_12 17 grydeAlellekaleiarrllGpdhpltattlrnLgrlyr.algryeeAlelleealaiaek 77
                 + ++A + l  a++ + +  G  +  +at ++nL+++y+ + g+ ++Ale +e+a + +e+
  EEA22660.1 40 TDPEDAVRVLAGAIQHYINK-GNFR-RAATHQQNLAECYEvEIGNAKKALEEYEKAAEWYES 99
                688999999999*9999888.5555.89***********66*****************9985 PP

  == domain 3  score: 3.3 bits;  conditional E-value: 0.034
      TPR_12   6 ln.nlaavlrrlgrydeAlelleka 29 
                 ++ ++a++ +   +y +A+ ++ek+
  EEA22660.1 109 YYlKVADLAAIEADYYKAIGYYEKV 133
                 44258899999999*****999985 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0       1.4   4.3e+03      11      22 ..      18      30 ..      11      45 .. 0.71
   2 ?   -3.2   0.0       4.1   1.2e+04      14      22 ..      41      49 ..      36      53 .. 0.72
   3 ?    0.2   0.0      0.32   9.6e+02       9      20 ..      56      67 ..      54      70 .. 0.86
   4 ?    7.2   1.2    0.0019       5.8       5      24 ..      80      99 ..      70     109 .. 0.82
   5 ?    5.1   0.1    0.0092        27      14      30 ..     122     136 ..     114     141 .. 0.81

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 1.4
       TPR_7 11 r.lGdyeeAiely 22
                + l++ ++A+  +
  EEA22660.1 18 NnLNEPDDAANSL 30
                4488888888655 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 4.1
       TPR_7 14 dyeeAiely 22
                d e+A++++
  EEA22660.1 41 DPEDAVRVL 49
                778888876 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.32
       TPR_7  9 ysrlGdyeeAie 20
                y + G++++A++
  EEA22660.1 56 YINKGNFRRAAT 67
                7789******97 PP

  == domain 4  score: 7.2 bits;  conditional E-value: 0.0019
       TPR_7  5 LarlysrlGdyeeAielyeq 24
                ++++  +l +ye+A+e ye 
  EEA22660.1 80 IGNAKKALEEYEKAAEWYES 99
                67777889999***999996 PP

  == domain 5  score: 5.1 bits;  conditional E-value: 0.0092
       TPR_7  14 dyeeAielyeqsLaltk 30 
                 dy +Ai++ye+  +   
  EEA22660.1 122 DYYKAIGYYEK--VGKV 136
                 7889******9..6655 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       1.8   5.3e+03      23      34 .]       8      19 ..       8      19 .. 0.75
   2 ?    0.8   0.0      0.22   6.7e+02      14      31 ..      20      37 ..      19      40 .. 0.81
   3 ?    2.7   0.1     0.056   1.7e+02      11      27 ..      56      72 ..      54      77 .. 0.79
   4 ?    8.8   0.3   0.00063       1.9      15      31 ..      81      97 ..      78     100 .. 0.56
   5 ?    2.5   1.8     0.065   1.9e+02       3      27 ..     109     133 ..     107     137 .. 0.80
   6 ?   -0.2   0.0       0.5   1.5e+03       3      17 ..     150     164 ..     149     165 .. 0.86

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.8
       TPR_2 23 afekAleldPnn 34
                afekA +   nn
  EEA22660.1  8 AFEKAAAVQRNN 19
                689998877765 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.22
       TPR_2 14 lgdyeeAleafekAleld 31
                l+++++A++ + +A + +
  EEA22660.1 20 LNEPDDAANSLSEAFKVY 37
                788999999999998765 PP

  == domain 3  score: 2.7 bits;  conditional E-value: 0.056
       TPR_2 11 yyklgdyeeAleafekA 27
                y+++g++ +A+ + +  
  EEA22660.1 56 YINKGNFRRAATHQQNL 72
                9999******9987765 PP

  == domain 4  score: 8.8 bits;  conditional E-value: 0.00063
       TPR_2 15 gdyeeAleafekAleld 31
                g+ ++Ale +ekA e +
  EEA22660.1 81 GNAKKALEEYEKAAEWY 97
                45556666666665544 PP

  == domain 5  score: 2.5 bits;  conditional E-value: 0.065
       TPR_2   3 alynlGlayyklgdyeeAleafekA 27 
                 ++   +++++   dy +A+ ++ek+
  EEA22660.1 109 YYLKVADLAAIEADYYKAIGYYEKV 133
                 56666777777889*********96 PP

  == domain 6  score: -0.2 bits;  conditional E-value: 0.5
       TPR_2   3 alynlGlayyklgdy 17 
                 + +  G +++++gd+
  EEA22660.1 150 YFFKAGICHLASGDL 164
                 67899*******996 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.0      0.78   2.3e+03      23      34 .]       8      19 ..       3      19 .. 0.77
   2 ?    0.3   0.0      0.24     7e+02      13      31 ..      19      37 ..      14      39 .. 0.83
   3 ?   -1.6   0.0      0.94   2.8e+03      11      20 ..      56      65 ..      52      68 .. 0.64
   4 ?   -2.9   0.0       2.5   7.4e+03       6      11 ..      71      76 ..      70      77 .. 0.77
   5 ?    9.7   0.2   0.00025      0.74       7      25 ..      80      98 ..      78      99 .. 0.93
   6 ?    3.1   0.8     0.032        96      16      27 ..     122     133 ..     115     133 .. 0.91

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.78
                HHHHHHHHSTTH CS
       TPR_1 23 yyekALelnPnn 34
                ++ekA  ++ nn
  EEA22660.1  8 AFEKAAAVQRNN 19
                799999888876 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.24
                HTT-HHHHHHHHHHHHHHS CS
       TPR_1 13 klgkydeAleyyekALeln 31
                +l+++d+A    ++A +++
  EEA22660.1 19 NLNEPDDAANSLSEAFKVY 37
                68999***99999998765 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 0.94
                HHHTT-HHHH CS
       TPR_1 11 yfklgkydeA 20
                y ++g++  A
  EEA22660.1 56 YINKGNFRRA 65
                5566666665 PP

  == domain 4  score: -2.9 bits;  conditional E-value: 2.5
                HHHHHH CS
       TPR_1  6 nlGnay 11
                nl+ +y
  EEA22660.1 71 NLAECY 76
                788888 PP

  == domain 5  score: 9.7 bits;  conditional E-value: 0.00025
                HHHHHHHTT-HHHHHHHHH CS
       TPR_1  7 lGnayfklgkydeAleyye 25
                +Gna   l++y++A e ye
  EEA22660.1 80 IGNAKKALEEYEKAAEWYE 98
                79****************8 PP

  == domain 6  score: 3.1 bits;  conditional E-value: 0.032
                 -HHHHHHHHHHH CS
       TPR_1  16 kydeAleyyekA 27 
                 +y +A+ yyek+
  EEA22660.1 122 DYYKAIGYYEKV 133
                 899*******95 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.1      0.48   1.4e+03      18      33 ..       3      18 ..       2      19 .. 0.80
   2 ?   -2.5   0.0       2.9   8.8e+03      17      26 ..      30      39 ..      25      39 .. 0.76
   3 ?   -1.8   0.0       1.8   5.3e+03      11      20 ..      56      65 ..      56      68 .. 0.83
   4 ?   11.7   1.1   7.9e-05      0.24       5      33 ..      70      99 ..      69     100 .. 0.89
   5 ?    3.1   1.8     0.047   1.4e+02       3      27 ..     109     133 ..     108     136 .. 0.89

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.48
                HHHHHHHHHHHHHHHH CS
       TPR_8 18 eeAkeyyekaleldpd 33
                +eA  ++eka   +++
  EEA22660.1  3 KEAGMAFEKAAAVQRN 18
                688899****888776 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 2.9
                HHHHHHHHHH CS
       TPR_8 17 yeeAkeyyek 26
                + eA ++y+k
  EEA22660.1 30 LSEAFKVYRK 39
                5688899987 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 1.8
                HHHTT-HHHH CS
       TPR_8 11 ylklgdyeeA 20
                y+++g++  A
  EEA22660.1 56 YINKGNFRRA 65
                8999999877 PP

  == domain 4  score: 11.7 bits;  conditional E-value: 7.9e-05
                HHHHHHH.HHTT-HHHHHHHHHHHHHHHHH CS
       TPR_8  5 ynlgsiy.lklgdyeeAkeyyekaleldpd 33
                +nl+ +y  + g+ ++A e yeka e+ ++
  EEA22660.1 70 QNLAECYeVEIGNAKKALEEYEKAAEWYES 99
                589999999***************999775 PP

  == domain 5  score: 3.1 bits;  conditional E-value: 0.047
                 HHHHHHHHHHHTT-HHHHHHHHHHH CS
       TPR_8   3 ayynlgsiylklgdyeeAkeyyeka 27 
                 +y++ +++     dy +A+ yyek+
  EEA22660.1 109 YYLKVADLAAIEADYYKAIGYYEKV 133
                 7899999999999*********996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (241 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       794  (0.0442858); expected 358.6 (0.02)
Passed bias filter:                      487  (0.0271627); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 1579.64
//
Query:       EEA22661.1  [L=540]
Description: small nucleolar ribonucleoprotein complex subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.1e-39  131.5   0.0    2.3e-35  120.2   0.0    3.4  3  BING4CT        BING4CT (NUC141) domain
    9.1e-08   32.3   0.0        7.9    6.8   0.0    5.7  6  ANAPC4_WD40    Anaphase-promoting complex subunit 4 WD40 doma
     0.0095   16.8   0.1         12    7.0   0.0    4.2  4  WD40           WD domain, G-beta repeat
  ------ inclusion threshold ------
      0.026   13.6   0.0      0.051   12.6   0.0    1.4  1  Coatomer_WDAD  Coatomer WD associated region


Domain annotation for each model (and alignments):
>> BING4CT  BING4CT (NUC141) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.12   5.5e+02       9      32 ..     197     220 ..     191     224 .. 0.82
   2 !    6.2   0.0     0.002       9.1      18      47 ..     248     277 ..     237     286 .. 0.86
   3 !  120.2   0.0   5.1e-39   2.3e-35       1      79 []     364     442 ..     364     442 .. 0.99

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.12
     BING4CT   9 gskieslrFvpfeDvlgvghskgi 32 
                 + + + l+F p++ +l+ + ++g+
  EEA22661.1 197 HVEAKYLEFLPYHFLLASAANSGF 220
                 4567889*********99999998 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.002
     BING4CT  18 vpfeDvlgvghskgissiivPGsGepnfda 47 
                  p++ +l vgh++g  ++  P s ++ + a
  EEA22661.1 248 NPWNAILHVGHQNGTVTLWSPNSQTALVKA 277
                 69999****************998887766 PP

  == domain 3  score: 120.2 bits;  conditional E-value: 5.1e-39
     BING4CT   1 pYlthklpgskieslrFvpfeDvlgvghskgissiivPGsGepnfdaleanpfetkkqrrereVrsLLeKlqpelItld 79 
                 pY+ +  +g++ie++r++p+eD+lgv h+kg+ siivPG+Ge+nfda+e np+et+kqr+e+eV++LL+Klqpe+I+ld
  EEA22661.1 364 PYMAWGGDGQRIETVRWCPYEDILGVTHDKGFASIIVPGAGEANFDATEVNPYETTKQRQEAEVKALLNKLQPEMISLD 442
                 7****************************************************************************98 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.0      0.11   4.9e+02      47      89 ..     126     166 ..     123     169 .. 0.81
   2 !    5.2   0.0    0.0057        25      36      62 ..     156     181 ..     145     193 .. 0.84
   3 ?    3.1   0.0     0.026   1.2e+02      37      78 ..     196     237 ..     189     244 .. 0.87
   4 !    5.7   0.0    0.0039        18      43      81 ..     244     282 ..     240     288 .. 0.83
   5 !    6.8   0.0    0.0018       7.9      38      90 ..     281     341 ..     275     343 .. 0.88
   6 ?    4.2   0.0     0.012        54      36      65 ..     370     399 ..     346     412 .. 0.85

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.11
  ANAPC4_WD40  47 kpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                    +gk L  a  +g+v  +d   gk+  +l+ +++  v   +W
   EEA22661.1 126 TRSGKNLLLAGRKGHVATMDWRAGKLGCELQLGET--VRDAKW 166
                  6789999***************9999888888766..655555 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0057
  ANAPC4_WD40  36 kedsevrsLaWkpdgklLavaysdgev 62 
                  + +++vr+ +W ++++++ava +++ v
   EEA22661.1 156 QLGETVRDAKWLHNNQFFAVAQKKN-V 181
                  56899****************9886.4 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.026
  ANAPC4_WD40  37 edsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsv 78 
                  +  e + L++ p   lLa a + g ++  d ++g++v +l++
   EEA22661.1 196 KHVEAKYLEFLPYHFLLASAANSGFLKYTDTSTGQLVAELPT 237
                  556778899999999**********************99876 PP

  == domain 4  score: 5.7 bits;  conditional E-value: 0.0039
  ANAPC4_WD40  43 sLaWkpdgklLavaysdgevrlldaesgkvvhslsvkse 81 
                  +L+ +p + +L v++++g+v l + +s++ + +  v++ 
   EEA22661.1 244 ALCQNPWNAILHVGHQNGTVTLWSPNSQTALVKALVHRG 282
                  678888999***************999998887777766 PP

  == domain 5  score: 6.8 bits;  conditional E-value: 0.0018
  ANAPC4_WD40  38 dsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksek........avtclgWg 90 
                   + vrs+a    g+ ++   +d ++++ d+   k vhs+s+ +          + t +gWg
   EEA22661.1 281 RGPVRSMAIDRLGRYMVSTGQDMRMNVWDIRMFKPVHSYSCYQPGssvaisdrNLTAVGWG 341
                  6789*************************************99887777777777777776 PP

  == domain 6  score: 4.2 bits;  conditional E-value: 0.012
  ANAPC4_WD40  36 kedsevrsLaWkpdgklLavaysdgevrll 65 
                  +++++++ ++W p + +L v +++g  +++
   EEA22661.1 370 GDGQRIETVRWCPYEDILGVTHDKGFASII 399
                  478999999999999999999999977665 PP

>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0      0.13   5.6e+02      13      38 .]     161     185 ..     131     185 .. 0.84
   2 ?    2.5   0.1     0.067     3e+02      16      38 .]     245     267 ..     229     273 .. 0.72
   3 !    7.0   0.0    0.0026        12      10      38 .]     280     309 ..     269     309 .. 0.91
   4 ?   -2.6   0.0       2.9   1.3e+04      12      25 ..     374     387 ..     366     394 .. 0.70

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.13
                 EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  13 vtslafspdgawlasGsdDgtvriWd 38 
                 v++ ++ ++++++a +  +++v+i+d
  EEA22661.1 161 VRDAKWLHNNQFFAVAQ-KKNVYIYD 185
                 7888899*****98655.99999998 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.067
                 EEEETTSSEEEEEETTSEEEEEE CS
        WD40  16 lafspdgawlasGsdDgtvriWd 38 
                 l+ +p +a l  G+ +gtv +W+
  EEA22661.1 245 LCQNPWNAILHVGHQNGTVTLWS 267
                 55444444443499999999995 PP

  == domain 3  score: 7.0 bits;  conditional E-value: 0.0026
                 S.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  10 H.ssvtslafspdgawlasGsdDgtvriWd 38 
                 H ++v+s+a ++ g++++s + D    +Wd
  EEA22661.1 280 HrGPVRSMAIDRLGRYMVSTGQDMRMNVWD 309
                 8888**************9999*******9 PP

  == domain 4  score: -2.6 bits;  conditional E-value: 2.9
                 SEEEEEEETTSSEE CS
        WD40  12 svtslafspdgawl 25 
                  +  ++++p+ + l
  EEA22661.1 374 RIETVRWCPYEDIL 387
                 48889999998886 PP

>> Coatomer_WDAD  Coatomer WD associated region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   1.1e-05     0.051     118     171 ..     131     185 ..      98     199 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.1e-05
                    XXXXXXXXX.XXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXX CS
  Coatomer_WDAD 118 alLgvksegsvsfYDweqgklvrridvkk.vknVvwsddgelvalvskdtvyils 171
                    +lL++  +g v+  Dw  gkl  ++++ + v++  w  +++++a+++k++vyi++
     EEA22661.1 131 NLLLAGRKGHVATMDWRAGKLGCELQLGEtVRDAKWLHNNQFFAVAQKKNVYIYD 185
                    6888888889****************9988***********************87 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (540 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1131  (0.0630822); expected 358.6 (0.02)
Passed bias filter:                      611  (0.0340789); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.64u 0.29s 00:00:00.93 Elapsed: 00:00:00.47
# Mc/sec: 3461.03
//
Query:       EEA22662.1  [L=809]
Description: pre-rRNA processing protein Tsr1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.1e-110  369.7   0.0     3e-110  368.3   0.0    1.7  2  RIBIOP_C  40S ribosome biogenesis protein Tsr1 and BMS1 C-ter
      1e-20   73.6   0.0    2.5e-20   72.4   0.0    1.7  1  AARP2CN   AARP2CN (NUC121) domain


Domain annotation for each model (and alignments):
>> RIBIOP_C  40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.2      0.22   1.9e+03      16      59 ..      29      77 ..      15     124 .. 0.54
   2 !  368.3   0.0  3.3e-114    3e-110       1     292 []     492     796 ..     492     796 .. 0.97

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.22
    RIBIOP_C 16 yrglkslrtsewdpken.....lpeeyarifefenfketkkrvlkeale 59
                + +lk+  + +++++e        ++    ++ +n  ++k++v +++++
  EEA22662.1 29 KSALKERTRGKIETNERgvrktPHQQLMSKLDRKNQARQKQQVKRQEKS 77
                4555555555555555544221111111122222222222222222222 PP

  == domain 2  score: 368.3 bits;  conditional E-value: 3.3e-114
    RIBIOP_C   1 vetpedvearerfakyrglkslrtsewdpken...lpeeyarifefenfketkkrvlkealeeregvegGtyvrleiknvpeelveeknfdekkplivf 96 
                 +e++++v arer++kyrgl+sl+ts w+++e+   +pe+++r+++f+++k  k+++++eal   +gv++Gt+v++++k vp+ l++     +  p+ +f
  EEA22662.1 492 IELHPNVLARERLQKYRGLRSLKTSRWETSEDrpfEPEDWRRLLQFNDYKGVKNKLIREALI--GGVTPGTRVNVHLKAVPSVLRN-----SPLPVALF 583
                 6899**********************************************************..*****************76666.....579***** PP

    RIBIOP_C  97 gllphEekvsvvnvrikrhreyekpikskdplifsvGfRrfqakPifsqed.tknnkhklerylkpghtcvatfygpitfpntpvlafkel........ 186
                 +ll+hE+k +v+n++++ ++++ekpiksk+++i+++G+Rr++++Pi+s +  t+nn+hk++ryl+pg++++at +gp+t++ +pvl+fk++        
  EEA22662.1 584 SLLRHEHKHTVININMTLNSSVEKPIKSKEEVIIQCGPRRLVVNPIYSGAGnTPNNVHKFDRYLHPGRSAIATYIGPVTWGAVPVLVFKNQavddpevl 682
                 **************************************************9669***********************************999******* PP

    RIBIOP_C 187 ........sskeasfrlvatGsvlevdpsriivkrivLtGhpfkihkktaviryMFfnpedvawFkpveLrTksGrrGhIkeslgthGyfkatFddklk 277
                          ++ ++++l+atG+v+ +d+sr+++kr++LtGhp+kihkk++++ryMFfn+edv+wFk+++L+T++Gr+G+IkeslgthGyfka+Fd+k++
  EEA22662.1 683 dsadgttaGKTGNRLELIATGTVVAPDHSRVVAKRAILTGHPYKIHKKVVTVRYMFFNSEDVHWFKALQLWTRRGRSGFIKESLGTHGYFKAMFDSKIN 781
                 *******9555899************************************************************************************* PP

    RIBIOP_C 278 qsDiVlmslYkrvfp 292
                 ++D V +slYkrvfp
  EEA22662.1 782 PQDSVGISLYKRVFP 796
                 *************98 PP

>> AARP2CN  AARP2CN (NUC121) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.4   0.0   2.7e-24   2.5e-20       1      84 [.     234     311 ..     234     312 .. 0.97

  Alignments for each domain:
  == domain 1  score: 72.4 bits;  conditional E-value: 2.7e-24
     AARP2CN   1 EilnllrfisvqkfrplswReqrpyiladrveiltdseskeeeskedrtlsveGyvrGsplsanqlvHipglGDfqiekieklp 84 
                 E++n++r +++++++ ++wR++r+++ +++v++ + + s         +++v+G+vrG++l+a++ vHipg+GDfqi++i+++p
  EEA22662.1 234 ECSNVVRGLCTATPKGIRWRDDRSWMTIQDVKWPDVPGSL------IDDVVVTGVVRGKGLKADRIVHIPGWGDFQIASITAAP 311
                 89**************************************......779*******************************9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (809 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1125  (0.0627475); expected 358.6 (0.02)
Passed bias filter:                      611  (0.0340789); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.70u 0.31s 00:00:01.01 Elapsed: 00:00:00.50
# Mc/sec: 4833.44
//
Query:       EEA22663.1  [L=275]
Description: urease accessory protein UreG, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.7e-34  117.8   0.0    4.5e-34  117.6   0.0    1.1  1  cobW      CobW/HypB/UreG, nucleotide-binding domain
      8e-05   21.7   0.0      0.032   13.2   0.0    2.1  2  MeaB      Methylmalonyl Co-A mutase-associated GTPase MeaB
  ------ inclusion threshold ------
      0.063   13.4   0.0       0.22   11.6   0.0    1.9  2  MMR_HSR1  50S ribosome-binding GTPase
      0.071   13.0   0.0       0.11   12.4   0.0    1.4  1  NACHT     NACHT domain
      0.085   12.9   0.0       0.14   12.3   0.0    1.5  1  CbiA      CobQ/CobB/MinD/ParA nucleotide binding domain
      0.091   12.8   0.0       0.12   12.4   0.0    1.3  1  ResIII    Type III restriction enzyme, res subunit
       0.12   12.9   0.0       0.16   12.4   0.0    1.2  1  AAA_23    AAA domain
       0.14   12.1   0.0       0.17   11.8   0.0    1.2  1  ATPase_2  ATPase domain predominantly from Archaea


Domain annotation for each model (and alignments):
>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.6   0.0     2e-37   4.5e-34       3     174 ..      61     228 ..      59     231 .. 0.93

  Alignments for each domain:
  == domain 1  score: 117.6 bits;  conditional E-value: 2e-37
                 EEEEESTTCCHHHHHHHHH.CT--SS-EEEEESS-SSCHCCCCCCHCCCT.....EEEETTTTECCH.CTT-HHHHHHHHHHHH..TT-SEEEEEECT. CS
        cobW   3 tvltGflGsGKTtLlnhll.enraglklavivNefgevsiDaellretgve....ivelenGciCct.lredllkelealeere..erldviliEttG. 92 
                 ++++G++GsGKT+L+ +l+ + r+++++a ++N++  +++Dae+l+++++     i  +e+G+++++ +red++++l al++++   + d++liE++G 
  EEA22663.1  61 IGIGGPVGSGKTALMLKLClALRDQYSIAAVTNDIF-TKEDAEFLTRNKALaperISAIETGGCPHAaVREDISANLLALQTLQrkFNTDLLLIESGGd 158
                 789***************999***************.********9997767888**********************999988755679*********7 PP

                 TTTHHHHHTTSHHHHHCCCECEEEEEEETTTH.CCHCCHHHHHHHHHHTSSEEEEE-HHHHCHC...HHHHHHHHHHHHTTS- CS
        cobW  93 laePapvafteeelksdltldavvavvDaknleaeeekieekaedqlaaadllvlnKtDlldee.allekleerlrqlnpeak 174
                 +++++ +         +  +d++++v+D+    a ++k ++k++ +++ +dllv+nK+Dl++++ a+l+++e+++ +++++ +
  EEA22663.1 159 NLAANYS---------RELADFIIYVIDV----AGGDKVPRKGGPGITGSDLLVINKIDLAEAVgADLSVMERDAGKIREGGP 228
                 7777777.........99***********....99******************************************998765 PP

>> MeaB  Methylmalonyl Co-A mutase-associated GTPase MeaB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.6   0.0    0.0015       3.4      28      58 ..      57      87 ..      46      95 .. 0.87
   2 !   13.2   0.0   1.4e-05     0.032     116     230 ..     142     252 ..     122     266 .. 0.75

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.0015
                -SEEEEEEE-TTSSHHHHHHHHHHHHHCTT- CS
        MeaB 28 raqvvGltGvPGaGkstlvealglelrrrGk 58
                ra  +G+ G  G+Gk  l+ +l l lr++  
  EEA22663.1 57 RAFTIGIGGPVGSGKTALMLKLCLALRDQYS 87
                8999*********************998754 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 1.4e-05
                 HHHHTT-SEEEEEEESSTTHHHHHHTT-SEEEEEEESSTTTTTTT--CCCHHH-SEEEEE---HHHHHHHHHHHHHHHHHCSTTBTTB--EEEEEBCCC CS
        MeaB 116 lleaaGfDvvlietvGvGqsevdvaevvdtfvvlllpeaGDelqgikkGileiaDiivvnkaDkkeaekaarelraaleleeekekeWrpkvlktsave 214
                 l   +  D +lie  G   +     e++d ++ ++  ++GD++       +  +D++v+nk D++ea  a   l+++ e +  k +e  p v   s ++
  EEA22663.1 142 LQRKFNTDLLLIESGGDNLAANYSRELADFIIYVIDVAGGDKVPRKGGPGITGSDLLVINKIDLAEAVGAD--LSVM-ERDAGKIREGGPTVF-GSVKH 236
                 55556678889999888888888899****************976554456679*********98886654..5444.344444455556665.56688 PP

                 TBSHHHHHHHHHHHHH CS
        MeaB 215 geGidelvdaieehre 230
                 g+G+d++v+ i + ++
  EEA22663.1 237 GNGVDHIVNLIVSSWK 252
                 9999999998876655 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0       3.7   8.3e+03      47      59 ..      29      41 ..      23      57 .. 0.60
   2 ?   11.6   0.0   9.9e-05      0.22       2      86 ..      61     179 ..      60     204 .. 0.58

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 3.7
                EEEEEECGGCSSH CS
    MMR_HSR1 47 eielvDtpGlieg 59
                + e++D pG + +
  EEA22663.1 29 SHEIYDGPGSYIN 41
                6688999996532 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 9.9e-05
                 EEEEESTTSSHHHHHHHHHTS......TEEESSSTTSSSSEEEEEEE..ETTEEEEEEECGGC................SSHHHHHHH........... CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltge......kaivsdkpgtTrdinegrvk..lkgkeielvDtpGl................iegaseekg........... 65 
                 ++i G   +GK+ L+ +l+ +       a v++  +t  d ++ + +  l  ++i  + t G                                     
  EEA22663.1  61 IGIGGPVGSGKTALMLKLCLAlrdqysIAAVTNDIFTKEDAEFLTRNkaLAPERISAIETGGCphaavredisanllalQ-------Tlqrkfntdlll 152
                 8999***************7511112245555555555555444433444457899999*99733333333333333330.......133333333333 PP

                 .......HHHHHHHHHC.TSEEEEEEETT CS
    MMR_HSR1  66 .......lgkaflalee.adlillvvdas 86 
                        l+ ++ +  e ad i++v+d++
  EEA22663.1 153 iesggdnLAANYSR--ElADFIIYVIDVA 179
                 33322225555553..3478888888865 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   4.8e-05      0.11       4      30 ..      62      88 ..      60     163 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 4.8e-05
                EEEC-TTTCHHHHHHHHHHHHCTS-SC CS
       NACHT  4 ilqGeaGsGKTtLlqklalawaegklp 30
                 + G+ GsGKT+L+ kl+la+++++  
  EEA22663.1 62 GIGGPVGSGKTALMLKLCLALRDQYSI 88
                57899****************998765 PP

>> CbiA  CobQ/CobB/MinD/ParA nucleotide binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   6.1e-05      0.14       9      78 ..      68     155 ..      62     235 .. 0.71

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 6.1e-05
                 TSSHHHHHHHHHHHHHHTT--EEEEEEEESSCCCCHHTTEB-HHHH..................CCHCCCHHHHHHCHCHHHH...EEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..................xxxxxxxxxxxxxxxxxxx.xxxxx RF
        CbiA   9 GvGKTtlaanLaralarrglrVllvDaDpqannlaileglendiep..................dlkrllellealgkkkall.lkiag 78 
                 G+GKT l ++L+ al + ++ +++v  D  ++ +a + +  + ++p                  d++  l  l++l++k++   l+i +
  EEA22663.1  68 GSGKTALMLKLCLALRD-QYSIAAVTNDIFTKEDAEFLTRNKALAPerisaietggcphaavreDISANLLALQTLQRKFNTDlLLIES 155
                 9****************.*******9999888877444444444446666666666666665554444444444444444444444443 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   5.3e-05      0.12      25      55 ..      59      89 ..      38     176 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 5.3e-05
                SEEEEEESTTSTHHHHHHHHHHHH-S..... CS
      ResIII 25 krglikmaTGtGKTlvaaklierllkkgkee 55
                  + i  + G+GKT +++kl+ +l+ ++++ 
  EEA22663.1 59 FTIGIGGPVGSGKTALMLKLCLALRDQYSIA 89
                456688899***************9987754 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   7.3e-05      0.16      23      67 ..      62     105 ..      58     169 .. 0.80

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 7.3e-05
      AAA_23  23 lItGpNGaGKTTildAiklaLygetprlsrksgrgfeksdveies 67 
                  I Gp G+GKT+++  ++laL  + +    +++  f k+d e+ +
  EEA22663.1  62 GIGGPVGSGKTALMLKLCLALRDQYSIAAVTND-IFTKEDAEFLT 105
                 599******************998877666432.44455555544 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   7.4e-05      0.17       2      47 ..      40      85 ..      39     147 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 7.4e-05
    ATPase_2  2 fdRekelkeleeilerepneiyfiYGpegsGKtaLlkeiienledk 47
                ++Re+ l++ e    ++++  + i Gp gsGKtaL+ ++   l+d+
  EEA22663.1 40 INREQPLSQHEGRDWKDRAFTIGIGGPVGSGKTALMLKLCLALRDQ 85
                6888888888888888889999999***********9998877663 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (275 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       294  (0.016398); expected 358.6 (0.02)
Passed bias filter:                      278  (0.0155056); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.40
# Mc/sec: 2064.91
//
Query:       EEA22664.1  [L=555]
Description: transposon, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.2e-33  116.3   0.0    2.2e-33  115.3   0.0    1.5  1  DDE_1        DDE superfamily endonuclease
    2.6e-10   40.2   0.4    1.7e-09   37.6   0.0    2.3  2  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
      2e-06   27.4   0.0    5.3e-06   26.1   0.0    1.7  1  HTH_psq      helix-turn-helix, Psq domain
  ------ inclusion threshold ------
      0.079   12.8   1.5       0.14   12.0   1.5    1.4  1  zf-CCHC_2    Zinc knuckle
       0.34   11.1   2.1       0.62   10.3   2.1    1.5  1  zf-CCHC      Zinc knuckle


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.3   0.0   6.2e-37   2.2e-33       2     175 .]     204     373 ..     203     373 .. 0.96

  Alignments for each domain:
  == domain 1  score: 115.3 bits;  conditional E-value: 6.2e-37
       DDE_1   2 erltvllcanaagsekLkplvigkak.sprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrle..aekrkilLlldssrshetvel.les 95 
                 ++++++++a  +++  +++++i+kak + r  ++   ++ ++d+++++++++w+t++i+ eWL  +f++ ++  + +++ +L+ld+++sh t+e+   +
  EEA22664.1 204 REWVTAIEATNSTGWAIPSYIIFKAKkNVRLGWF---DDLPSDWRINISENGWTTDQIGLEWLkTHFIPYINgrSMGSYRMLILDGHGSHLTAEFdRTC 299
                 7899********************9725677888...99*********************************99*********************9*** PP

       DDE_1  96 elqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                  ++ni  +++P++s++llqPld+g+++ lK++Y +q+ q + ++ n+++k       ld+l    kA++ a + +ti+++f
  EEA22664.1 300 TENNIIPICMPPHSSHLLQPLDVGCFAVLKRHYGQQVEQRMRDGFNHIDK-------LDFLMAFPKARTeAYKARTIQNSF 373
                 **************************************************.......9**********9999999999987 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.6   0.0   4.7e-13   1.7e-09       2      61 ..      70     125 ..      69     130 .. 0.90
   2 ?   -0.3   0.2      0.31   1.1e+03      14      35 ..     483     504 ..     481     527 .. 0.79

  Alignments for each domain:
  == domain 1  score: 37.6 bits;  conditional E-value: 4.7e-13
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT.S CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh.g 61 
                  + +E++L++W+ +l++rg p++++l+re+ + l+     l++++++++k+W+ + +kR  +
   EEA22664.1  70 QSEEDSLVKWVLDLDRRGLPPRHSLVREMVNYLL-----LQHGKPQVGKNWVTNLIKRRpE 125
                  578*****************************95.....6679***************854 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.31
                  HHC-CT---SCHHHHHHHHHHH CS
  HTH_Tnp_Tc5  14 qlrergipitgelirekAqela 35 
                  q  +++i+i + + re+Aq+l 
   EEA22664.1 483 QKSKKHISIEQGITREEAQALV 504
                  4578999999*********996 PP

>> HTH_psq  helix-turn-helix, Psq domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.1   0.0   1.5e-09   5.3e-06       2      41 ..      16      56 ..      15      59 .. 0.93

  Alignments for each domain:
  == domain 1  score: 26.1 bits;  conditional E-value: 1.5e-09
     HTH_psq  2 pealaaAleavvnGk.mSirkAArkYgiPrsTLwrrkrgky 41
                + ++++A+ +  nG  + ir+A r+Y+iPr+TL+ r++g++
  EEA22664.1 16 EGKIQLAISDLKNGRiLNIREATRIYDIPRTTLRDRLKGIE 56
                678999****9***************************986 PP

>> zf-CCHC_2  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   1.5   3.9e-05      0.14       5      20 ..     535     550 ..     531     551 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 3.9e-05
   zf-CCHC_2   5 vChiCgkkGHyIqdCP 20 
                  C  Cg+ GH I+ CP
  EEA22664.1 535 RCSGCGVEGHRINRCP 550
                 6888************ PP

>> zf-CCHC  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   2.1   0.00017      0.62       3      18 .]     536     551 ..     534     551 .. 0.89

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00017
                 TSSSSSSSSTTTTSTS CS
     zf-CCHC   3 CynCGepGHiardCpk 18 
                 C  CG +GH+ + Cp+
  EEA22664.1 536 CSGCGVEGHRINRCPS 551
                 777***********96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (555 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       967  (0.053935); expected 358.6 (0.02)
Passed bias filter:                      547  (0.0305092); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.61u 0.24s 00:00:00.85 Elapsed: 00:00:00.43
# Mc/sec: 3858.92
//
Query:       EEA22665.1  [L=258]
Description: GPI anchored protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (258 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       472  (0.0263261); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.44
# Mc/sec: 1776.51
//
Query:       EEA22666.1  [L=755]
Description: PtaB protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.5e-57  193.7   0.1    3.5e-57  193.7   0.1    4.6  3  LIM_bind     LIM-domain binding protein


Domain annotation for each model (and alignments):
>> LIM_bind  LIM-domain binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?  -22.1  27.0         1   1.8e+04     157     213 ..     103     166 ..      79     250 .. 0.57
   2 ?  -12.7  23.7         1   1.8e+04     152     203 ..     286     340 ..     259     371 .. 0.67
   3 !  193.7   0.1   1.9e-61   3.5e-57       3     240 ..     382     614 ..     381     615 .. 0.95

  Alignments for each domain:
  == domain 1  score: -22.1 bits;  conditional E-value: 1
    LIM_bind 157 a........ssaspkvskkvskrqg.ifgklsskepaeeppeavkqlpsspvn........sfGitesvmrfLe 213
                 +        s++++ +++++++rq+ i+++++  ++++++            +        ++G++++ ++ ++
  EEA22666.1 103 QqqpyamnvSNNAQLLQQQAMARQQrILQQQHLVQQQQHH----------AGGipvsmpagTQGLSQAQLSAMQ 166
                 1223333333333334444444444333333332222222..........222222222245555554444444 PP

  == domain 2  score: -12.7 bits;  conditional E-value: 1
    LIM_bind 152 qllesassaspkvskkvskrqg.ifgklsskepaeeppeavkqlpsspvn..sfG 203
                 + ++++ +a++++++++s++q  + +++++ +p + +p+  +q++++p++  ++ 
  EEA22666.1 286 PQHQQIPQAQQSMAQQQSQQQAqANQQQQQVQPPQAQPQNGQQQVAQPQQqaQLN 340
                 3445556777778888887777555555555555445556666666666533333 PP

  == domain 3  score: 193.7 bits;  conditional E-value: 1.9e-61
    LIM_bind   3 llelierlsnrs..nedsdieyWrkfvaefFs.........pdavlrltlkldeqekepkqFeittpllPryfrtlfesgvkslqlildgareqvlsng 90 
                 +++++e+ls+++  +ed+d+ +W+++v+++++         p++vlr+ +    +++++k+Fe+++++lPry++tlf++g++++q++++ ++e++ +ng
  EEA22666.1 382 VNSYFETLSTFQsnGEDADLLFWQEVVNKYYNttfqpmtgqPWGVLRQGVLT--AGTGSKSFEVNATILPRYYVTLFNNGIRRIQTHMEATQEFSPQNG 478
                 5789********99**************************************..667****************************************** PP

    LIM_bind  91 sivlecdkatfvytyedgsrvvlegqlrvlfdadlkIewlefavrsheeliprsalekklkqllesa.ssaspkvskkvskrqgifgklsskepaeepp 188
                 + v+ ++ka+f+y++ +++++ ++g+l+vl+++d k+++++++v++++e+iprs l++      e + ++ sp+v+k++skr++       k++ ++p+
  EEA22666.1 479 YRVVFSPKASFIYWFANDCQLFVNGSLKVLVNPDYKFDLVDISVSGFREFIPRSLLQQP-----EPIdTKPSPRVAKNTSKRMQ-------KQQLAQPT 565
                 *****************************************************999888.....33349*************99.......66777777 PP

    LIM_bind 189 eavkqlpsspvnsfGitesvmrfLeiaevmssmkdLmsfskknnilsPleaL 240
                     + p+s vn++G+++sv+ fLeiae +s+m++L+s+s++n+++s  e L
  EEA22666.1 566 ---ISPPESLVNENGLPHSVQCFLEIAEPLSYMTSLISHSASNPHKSASELL 614
                 ...89******************************************99887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (755 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3187  (0.177757); expected 358.6 (0.02)
Passed bias filter:                      588  (0.032796); expected 358.6 (0.02)
Passed Vit filter:                       186  (0.0103743); expected 17.9 (0.001)
Passed Fwd filter:                        76  (0.00423894); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 1.75u 0.40s 00:00:02.15 Elapsed: 00:00:00.59
# Mc/sec: 3861.76
//
Query:       EEA22667.1  [L=1415]
Description: mitochondrial AAA ATPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.1e-52  177.6   0.3    3.1e-52  177.6   0.3    3.4  3  DUF4050       Protein of unknown function (DUF4050)
    4.8e-40  137.0   0.0    7.1e-38  130.0   0.0    2.9  2  AAA           ATPase family associated with various cellular 
    4.8e-11   42.3   0.0    1.3e-10   40.9   0.0    1.8  1  AAA_lid_3     AAA+ lid domain
      8e-05   23.1   0.1     0.0027   18.1   0.0    3.0  3  AAA_16        AAA ATPase domain
    0.00014   21.6   0.0    0.00037   20.3   0.0    1.6  1  RuvB_N        Holliday junction DNA helicase RuvB P-loop doma
    0.00042   20.6   0.3      0.067   13.5   0.1    3.4  3  AAA_22        AAA domain
    0.00075   19.7   0.0     0.0032   17.6   0.0    2.2  1  AAA_33        AAA domain
    0.00087   18.6   0.3     0.0041   16.4   0.0    2.0  2  TIP49         TIP49 P-loop domain
     0.0033   17.4   0.0     0.0093   16.0   0.0    1.9  1  AAA_5         AAA domain (dynein-related subfamily)
  ------ inclusion threshold ------
      0.018   15.1   0.0      0.074   13.1   0.0    2.0  2  AAA_14        AAA domain
      0.021   14.5   0.0      0.044   13.5   0.0    1.4  1  IstB_IS21     IstB-like ATP binding protein
      0.026   14.8   0.0        0.1   12.8   0.0    2.1  1  AAA_28        AAA domain
      0.035   13.5   0.1       0.08   12.3   0.1    1.5  1  Mg_chelatase  Magnesium chelatase, subunit ChlI
      0.063   13.7   0.0       0.18   12.2   0.0    1.8  1  RNA_helicase  RNA helicase
      0.082   12.6   0.0       0.22   11.2   0.0    1.8  1  AAA_24        AAA domain
      0.094   12.1   0.0        3.4    7.1   0.0    2.4  2  TniB          Bacterial TniB protein
      0.097   13.2   0.0       0.25   11.9   0.0    1.7  1  AAA_18        AAA domain


Domain annotation for each model (and alignments):
>> DUF4050  Protein of unknown function (DUF4050)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   2.4       2.2   2.3e+03      83     149 ..      56     142 ..      25     177 .. 0.57
   2 ?   -1.4   0.1       2.3   2.5e+03      83     121 ..     370     411 ..     282     422 .. 0.58
   3 !  177.6   0.3   2.9e-55   3.1e-52       1     183 []    1082    1302 ..    1082    1302 .. 0.78

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 2.2
     DUF4050  83 s........ealeeqsaessssssasatattspas.........seeseeeesvetlvPvappllppsnpiras...ItpasYpsiY 149
                 s         ++++q ae+++ s++s+++++ ++s         +e++  +e+      + + +++ + + +a+   I+p++Y + +
  EEA22667.1  56 SdtrngvqpIDMNAQPAEHAQDSTNSNQSSAGRKSyisglrrtwKEKKPLSEDASATATIPQWFIDRNVVTYAQavdIPPQLYVKSF 142
                 122334444444444444444444444444444446677777764444444555555556666666444444422236666665555 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 2.3
     DUF4050  83 s.........ealeeqsaessssssasatattspasseeseeeesvet 121
                 s         +      + +s+++ as+++t+++++++ ++++ s +t
  EEA22667.1 370 SawmrvinqlT------SIASQNQPASSDSTATQDTKTGKKPDMSPKT 411
                 13332222222......2222222222233333333344444444444 PP

  == domain 3  score: 177.6 bits;  conditional E-value: 2.9e-55
     DUF4050    1 spfrfdspdsvssavtsnqslderkrkrrraleeemkwNeGlalWearRdaWtgartvrkkekkerep.......................seaesa 74  
                  +p+rf++p++++++v       er r+rr +le+emkwN Gl+++ +rRdaWtgar++r++ ++  ++                       +     
  EEA22667.1 1082 DPYRFENPNAIKTSVL------ERGRRRRADLEQEMKWNPGLRFYIERRDAWTGARKRRDVGQRTAKRqralinilsresknsktiglngdA----- 1167
                  59*************7......9**************************************9998888666666665555555555555550..... PP

     DUF4050   75 sseesssss....................ealeeqsaessssssasatattspas...................seeseeeesvetlvPvappllpp 132 
                                               e    + + s+++s  ++t+tt++++                    +++++ +s+e ++Pv+++++++
  EEA22667.1 1168 --------GakvesltdatssaqqsrdllE----DLSLSEKKSR-DTTPTTDNNTsnedygldgstgddgdiedYDDDHSFDSDESMIPVMESFIDA 1251
                  ........0555555444444333433332....2222222222.122222222235567999999******998899******************* PP

     DUF4050  133 snpirasItpasYpsiYsklvvqsktpsvpInLsdmikalVqgWkadgeWp 183 
                  snp+r+sItpa+Y s+Ysk++vq++tp++pInL+d++kalV+gWkadg+Wp
  EEA22667.1 1252 SNPVRSSITPALYASLYSKVIVQGLTPTIPINLADVTKALVAGWKADGQWP 1302
                  **************************************************9 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.8   0.0     0.068        72      57     110 ..     403     455 ..     365     461 .. 0.85
   2 !  130.0   0.0   6.7e-41   7.1e-38       1     131 [.     709     837 ..     709     838 .. 0.95

  Alignments for each domain:
  == domain 1  score: 3.8 bits;  conditional E-value: 0.068
                 S....TS.EEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTSSSTEEEEEEES CS
         AAA  57 a....kp.silfiDEidalaksrsgseseeeervvnqLlteldgvkkkeskvivigatn 110
                 +    +p +i+ i +  +l+++r      e+++ +  Ll ++   +++ +++++ig++ 
  EEA22667.1 403 KkpdmSPkTIIHIQDYVELMQTR------EGSKFLRLLLDAIHSRRREGHRILLIGTSS 455
                 233465779**************......999************************986 PP

  == domain 2  score: 130.0 bits;  conditional E-value: 6.7e-41
                 EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHH..TTCCCHHHHHHHHHHHHHHHHTT CS
         AAA   1 vllyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksr..sgseseeeervvnqLlteldgvk 97 
                 +llyGppGtGKTllakava+e+g+++le+sgs++ ++yvge+ek++r++f+ ak+ + p+++fiDE+da+++sr  s++  +++++++nq+l+e+dg++
  EEA22667.1 709 MLLYGPPGTGKTLLAKAVARESGATVLEVSGSDIYDMYVGEGEKNVRAIFTLAKKLS-PCVVFIDEADAIFGSRnqSRNRFSSHRELINQFLREWDGMN 806
                 89******************************************************9.****************8878888999*************** PP

                 TSSSTEEEEEEESSGGGSTHHHHSTTSSEEEETT CS
         AAA  98 kkeskvivigatnrpdkldpallrgRfdrkieie 131
                 + +   ++++atnrp +ld+a+l +R+ r++ ++
  EEA22667.1 807 DMS--AFIMVATNRPFDLDDAVL-RRLPRRLLVD 837
                 *63..69999*************.7*99998765 PP

>> AAA_lid_3  AAA+ lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.9   0.0   1.3e-13   1.3e-10       1      44 [.     860     920 ..     860     921 .. 0.77

  Alignments for each domain:
  == domain 1  score: 40.9 bits;  conditional E-value: 1.3e-13
   AAA_lid_3   1 dvdlkeLAerTeGySGADlaalcreAallAlrr.................gikeitmedfe 44 
                 +vdl++LA+rT+ ySG Dl+++c +Aal ++r+                  + ++t+++fe
  EEA22667.1 860 SVDLADLARRTPFYSGSDLKNVCVAAALTCVREeyenktqhtgetpyhypERRTLTQSHFE 920
                 69*******************************5555555555555444446667777776 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       4.8     5e+03     102     138 ..     398     449 ..     356     451 .. 0.42
   2 !   18.1   0.0   2.5e-06    0.0027      20      51 ..     702     733 ..     695     751 .. 0.76
   3 ?    0.4   0.0      0.71   7.4e+02     125     147 ..     756     777 ..     750     801 .. 0.72

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 4.8
      AAA_16 102 eealaavpelagaea...............srllellkrllallsrderplv 138
                 ++ ++  p+++++                 s +l+ll +++   +r+++ ++
  EEA22667.1 398 DTKTGKKPDMSPKTIihiqdyvelmqtregSKFLRLLLDAIHSRRREGHRIL 449
                 2333333333333333333333333335556677777777744444355343 PP

  == domain 2  score: 18.1 bits;  conditional E-value: 2.5e-06
      AAA_16  20 rsgrpelvllsGesGvGKsslvrellralekd 51 
                 +s+  + +ll+G++G+GK+ l+++++r+  ++
  EEA22667.1 702 ASDKIPGMLLYGPPGTGKTLLAKAVARESGAT 733
                 4444499*******************855444 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.71
      AAA_16 125 rllallsrderplvlvlDdlqwa 147
                 +++ l+++  +p v+++D+++ +
  EEA22667.1 756 AIFTLAKK-LSPCVVFIDEADAI 777
                 44477777.778********954 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0   3.5e-07   0.00037      35      92 ..     708     773 ..     701     780 .. 0.73

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 3.5e-07
      RuvB_N  35 hvllyGpPGlGkttlakiiakelgvklkitsgPvl......ekagdlaalltnleekd..vlfide 92 
                  +llyGpPG Gkt lak +a+e g+++   sg  +      e ++++ a++t  ++    v+fide
  EEA22667.1 708 GMLLYGPPGTGKTLLAKAVARESGATVLEVSGSDIydmyvgEGEKNVRAIFTLAKKLSpcVVFIDE 773
                 589************************999998773333333456677766655543333777777 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0       2.7   2.8e+03     106     130 ..     425     453 ..     367     460 .. 0.66
   2 !   13.5   0.1   6.4e-05     0.067       8      29 ..     709     730 ..     707     759 .. 0.86
   3 ?    3.0   0.0      0.11   1.1e+02      91     108 ..     762     787 ..     741     817 .. 0.65

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 2.7
      AAA_22 106 eealeeLrsllnl....srkgvqliLvGt 130
                  e  ++Lr ll+     +r g +++L+Gt
  EEA22667.1 425 REGSKFLRLLLDAihsrRREGHRILLIGT 453
                 34444555555555555666666666666 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 6.4e-05
      AAA_22   8 lvvtGesGtGKTtllrrlleql 29 
                 ++++G++GtGKT+l++ ++++ 
  EEA22667.1 709 MLLYGPPGTGKTLLAKAVARES 730
                 589**************99875 PP

  == domain 3  score: 3.0 bits;  conditional E-value: 0.11
      AAA_22  91 v...ielliiDEaqhlr.....seea 108
                 +   + ++ iDEa+ ++     s + 
  EEA22667.1 762 KklsPCVVFIDEADAIFgsrnqSRNR 787
                 134569*********98864432332 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0     3e-06    0.0032       3      45 ..     710     785 ..     709     841 .. 0.68

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 3e-06
      AAA_33   3 llvGlpGsGKstlaerllkklgavllssdt.................................lrrrlfgtdqqsk 45 
                 ll G+pG+GK+ la+ ++++ ga++l+                                    + +++fg+ +qs 
  EEA22667.1 710 LLYGPPGTGKTLLAKAVARESGATVLEVSGsdiydmyvgegeknvraiftlakklspcvvfidEADAIFGSRNQSR 785
                 688*******************777654433345555555555555555555555555555554445555444444 PP

>> TIP49  TIP49 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0   3.9e-06    0.0041      47      97 ..     705     751 ..     695     760 .. 0.83
   2 ?   -1.1   0.1      0.78   8.2e+02      27      62 ..    1136    1170 ..    1126    1185 .. 0.85

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 3.9e-06
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49  47 klaGravLlaGpsgtGktalaiaiskelgedvpfvalsgsevyslevkkte 97 
                 k+   ++Ll Gp+gtGkt la a+++e g+ v    +sgs++y + v   e
  EEA22667.1 705 KIP--GMLLYGPPGTGKTLLAKAVARESGATV--LEVSGSDIYDMYVGEGE 751
                 555..68********************99655..799******98877666 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.78
                  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49   27 vGqkkareaagvivelikekklaGravLlaGpsgtG 62  
                  vGq +a++  ++i  l +e k + +++ l G++g+ 
  EEA22667.1 1136 VGQRTAKRQRALINILSRESKNS-KTIGLNGDAGAK 1170
                  9***********99999999977.********9985 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   8.8e-06    0.0093       2      34 ..     709     741 ..     708     830 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 8.8e-06
                 EEEE--SSSSHHHHHHHGGGGBS--EEEEE--T CS
       AAA_5   2 vlLvGppGtgKselaerlaaalnreveyvqltr 34 
                 +lL GppGtgK+ la+ +a+  +++v++v +++
  EEA22667.1 709 MLLYGPPGTGKTLLAKAVARESGATVLEVSGSD 741
                 79******************9999999998775 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0     7e-05     0.074       6      76 ..     710     777 ..     707     811 .. 0.84
   2 ?   -3.0   0.0       6.6     7e+03      47      77 ..     917     944 ..     890     949 .. 0.63

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 7e-05
      AAA_14   6 vitGaRrvGKTtllkqlikellvkkesilyinldderdkkladpekllelileklkeekktylflDEiqev 76 
                 ++ G+  +GKT l+k +++e+      +l+++  d  d    + ek+ ++i+ ++k+    ++f+DE+  +
  EEA22667.1 710 LLYGPPGTGKTLLAKAVARESG---ATVLEVSGSDIYDMYVGEGEKNVRAIFTLAKKLSPCVVFIDEADAI 777
                 789******************9...9************888877788899999877768899*****9876 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 6.6
      AAA_14  47 adpekllelileklkeekktylflDEiqevp 77 
                 +++e+ +e+i +++    + +  lDEi + +
  EEA22667.1 917 SHFERAMEEISASI---SEDMSSLDEIRKFD 944
                 23334444444444...45678899998876 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   4.2e-05     0.044      49      86 ..     708     745 ..     703     788 .. 0.71

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 4.2e-05
   IstB_IS21  49 nivllGpsGvGKshlaialgveavraglsvlfvrvedL 86 
                 +++l Gp+G+GK+ la a+++e  ++ l+v+   + d+
  EEA22667.1 708 GMLLYGPPGTGKTLLAKAVARESGATVLEVSGSDIYDM 745
                 5799***************9987666666655555554 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   9.6e-05       0.1       4      46 ..     711     754 ..     709     802 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 9.6e-05
      AAA_28   4 itGgestGKTtlleaLaar.gypvvpEaareileeklakgedal 46 
                 + G+++tGKT l++a a++ g +v++ ++ +i++    +ge++ 
  EEA22667.1 711 LYGPPGTGKTLLAKAVAREsGATVLEVSGSDIYDMYVGEGEKNV 754
                 89***************986777777778888777666666655 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.1   7.6e-05      0.08      25      42 ..     709     726 ..     702     734 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 7.6e-05
  Mg_chelatase  25 lllvGppGsGKtmlakrl 42 
                   +ll+GppG+GKt+lak++
    EEA22667.1 709 MLLYGPPGTGKTLLAKAV 726
                   89*************987 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00017      0.18       2      33 ..     710     741 ..     709     759 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00017
  RNA_helicase   2 wlyGpsgeGKStlakeLakallkklklkkkds 33 
                   +lyGp+g+GK++lak +a++   ++ + + ++
    EEA22667.1 710 LLYGPPGTGKTLLAKAVARESGATVLEVSGSD 741
                   79**************8887665554443333 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   0.00021      0.22       5      23 ..     709     729 ..     707     817 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00021
      AAA_24   5 iliyGpsgiGKTtlakel..g 23 
                 +l+yGp+g+GKT lak    +
  EEA22667.1 709 MLLYGPPGTGKTLLAKAVarE 729
                 79*************988542 PP

>> TniB  Bacterial TniB protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.0    0.0032       3.4      32      59 ..     703     730 ..     697     742 .. 0.86
   2 ?    2.3   0.0     0.094        99     109     152 ..     755     797 ..     745     800 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0032
        TniB  32 rkrmpnlllvGdsnnGKtmivekFarlh 59 
                 ++++p +ll+G++ +GKt +++  ar+ 
  EEA22667.1 703 SDKIPGMLLYGPPGTGKTLLAKAVARES 730
                 6899****************99888776 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.094
        TniB 109 qqvlrllrelkvrvLiiDEihnllagsarkqreflnalksLgne 152
                 +++ +l ++l++ v+ iDE + +  gs+++ r+ + + + L n+
  EEA22667.1 755 RAIFTLAKKLSPCVVFIDEADAIF-GSRNQSRNRFSSHRELINQ 797
                 55667889999999******9999.9999999999999999887 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   0.00024      0.25       2      25 ..     710     739 ..     709     799 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00024
      AAA_18   2 lltGtpGvGKttlakeLskrlgf......g 25 
                 ll G+pG+GKt lak+++++ g       g
  EEA22667.1 710 LLYGPPGTGKTLLAKAVARESGAtvlevsG 739
                 689**************9986333443342 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1415 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       669  (0.0373138); expected 358.6 (0.02)
Passed bias filter:                      437  (0.0243739); expected 358.6 (0.02)
Passed Vit filter:                        72  (0.00401584); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              17  [number of targets reported over threshold]
# CPU time: 1.08u 0.35s 00:00:01.43 Elapsed: 00:00:00.58
# Mc/sec: 7368.32
//
Query:       EEA22668.1  [L=411]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.5e-33  115.0   0.0    3.5e-33  114.6   0.0    1.2  1  DUF3237        Protein of unknown function (DUF3237)
     0.0014   18.6   6.3       0.31   11.1   1.3    2.4  2  zf-BED         BED zinc finger
  ------ inclusion threshold ------
      0.084   13.2   4.8        5.5    7.4   0.6    2.3  2  zf-C2H2_2      C2H2 type zinc-finger (2 copies)
       0.19   11.8   9.5        1.4    9.0   2.3    2.3  2  Zn_Tnp_IS91    Transposase zinc-binding domain


Domain annotation for each model (and alignments):
>> DUF3237  Protein of unknown function (DUF3237)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.6   0.0   7.7e-37   3.5e-33       1     148 [.     258     409 ..     258     410 .. 0.95

  Alignments for each domain:
  == domain 1  score: 114.6 bits;  conditional E-value: 7.7e-37
                 --EEEEEEEEEEE---EEEEEET.EEEEEEEEEEEEEESTT--EEE-ST-EEEEEE-TTS-EEEEEEEEEEETT..S-EEEEEEEEEEE--GGGHHHHH CS
     DUF3237   1 Pslepaftlevkleapvpigegp.gkrnivpitgGtikgprldgevlpgGaDwiridpggtarldaryvlktdd..galiyirytGvvtldeevlavlg 96 
                 Ps e  f++++kl+++v+ig++  g r +v++ gG++ g++ +g +lpgG+D + + ++  ++l a+yvl+ +d  +a+i ++ +G++t+ ++vl++l+
  EEA22668.1 258 PSIELDFRMSIKLNPKVSIGSSLwGGRDWVSFLGGQWAGRWGKGIILPGGQDSQVTVKEMATSLSANYVLQSSDepPAYIIVKAQGWLTGAKDVLEKLQ 356
                 88999*********99*****99***********************************9999*********988778********************** PP

                 H.T-..---GGG-EEEEEEEEEESSGGGGGGGSS-EEEEEEEESSEEEEEEEE CS
     DUF3237  97 g.gekkesspteygfrthptfetgdekykwLnnavfvGsgrfrvegveykvye 148
                 + + +++ +pt y++r+++++e+gde+y+ +n++++vGsg +r+ +v+ ++++
  EEA22668.1 357 DpNHADTINPTSYKYRLNLSMESGDERYAFVNTVMWVGSGCRRGHEVILDAFR 409
                 9744457789*****************************************98 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.1   1.3     7e-05      0.31      16      44 .]      30      61 ..      28      61 .. 0.87
   2 !    9.8   0.3   0.00018      0.79      16      40 ..     200     222 ..     184     226 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 7e-05
                --EETTTTEE----SSTHHHHHHH.....HHS-H CS
      zf-BED 16 kavCryCgkilsrgggttnLkrHL.....rrkHp 44
                +++C+yC  i +   +t++ k+HL      r+Hp
  EEA22668.1 30 SVQCIYCQQIRAK--NTSRQKQHLlecpgLRGHP 61
                589****999888..9********8888888886 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00018
                 --EETTTTEE----SSTHHHHHHHH CS
      zf-BED  16 kavCryCgkilsrgggttnLkrHLr 40 
                 +++C+yC  + +   +t++ ++HL 
  EEA22668.1 200 SVQCIYCQQVRAK--NTSRQRQHLL 222
                 79******99998..8*******95 PP

>> zf-C2H2_2  C2H2 type zinc-finger (2 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   0.3    0.0013         6      50      71 ..      30      52 ..      19      67 .. 0.86
   2 ?    7.4   0.6    0.0012       5.5      50      71 ..     200     222 ..     185     231 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0013
   zf-C2H2_2 50 kleClyCeke.fkslealreHmk 71
                +++C+yC++   k+++  ++H+ 
  EEA22668.1 30 SVQCIYCQQIrAKNTSRQKQHLL 52
                479*****997889999999985 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0012
   zf-C2H2_2  50 kleClyCeke.fkslealreHmk 71 
                 +++C+yC++   k+++  r+H+ 
  EEA22668.1 200 SVQCIYCQQVrAKNTSRQRQHLL 222
                 489****9997889999999985 PP

>> Zn_Tnp_IS91  Transposase zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.8    0.0014       6.4      53      83 ..      26      55 ..      13      58 .. 0.87
   2 ?    9.0   2.3   0.00031       1.4      54      88 ..     197     230 ..     192     232 .. 0.90

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0014
  Zn_Tnp_IS91 53 fsCksrhCpsCqkkateewlekqqeellpvp 83
                   C s  C  Cq+ +++++  +q+++ll++p
   EEA22668.1 26 DPCLSVQCIYCQQIRAKNTS-RQKQHLLECP 55
                 579999************99.9******997 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00031
  Zn_Tnp_IS91  54 sCksrhCpsCqkkateewlekqqeellpvpyrhvv 88 
                  +C s  C  Cq+ +++++  +q+++ll++p +  v
   EEA22668.1 197 KCLSVQCIYCQQVRAKNTS-RQRQHLLECPTYLNV 230
                  699999************9.9*********98776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (411 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       599  (0.0334096); expected 358.6 (0.02)
Passed bias filter:                      379  (0.0211389); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.49
# Mc/sec: 2499.71
//
Query:       EEA22669.1  [L=1599]
Description: acetylglutamate kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.6e-55  185.2   0.1    1.6e-54  184.1   0.1    1.5  1  NAT             NAT, N-acetyltransferase, of N-acetylglutamat
      5e-30  104.4   0.0    1.4e-29  103.0   0.0    1.8  1  Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domai
    1.2e-29  102.7   0.0    2.4e-29  101.7   0.0    1.5  1  Rad21_Rec8_N    N terminus of Rad21 / Rec8 like protein
    6.8e-28   97.9   0.0    1.2e-27   97.1   0.0    1.4  1  AA_kinase       Amino acid kinase family
  ------ inclusion threshold ------
      0.024   13.9   0.0      0.056   12.7   0.0    1.5  1  Rad21_Rec8      Conserved region of Rad21 / Rec8 like protein
      0.039   14.1   0.0       0.14   12.3   0.0    2.0  1  DapB_N          Dihydrodipicolinate reductase, N-terminus


Domain annotation for each model (and alignments):
>> NAT  NAT, N-acetyltransferase, of N-acetylglutamate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  184.1   0.1   5.2e-58   1.6e-54       1     169 [.     334     502 ..     334     503 .. 0.98

  Alignments for each domain:
  == domain 1  score: 184.1 bits;  conditional E-value: 5.2e-58
                 GHHHHHHSSSTSSEEEE---XEEEESSCCCSSXCCHHHHHHTTST...TTSSXHHHHHHHHHTSXEEEEEETTXSEEEEE.....EXSSSSXEEEEEEE CS
         NAT   1 dlqkelftdsgagtlirrGlkvitvkslkelidlekLksliedsf...krkldvkdYldrlkgkiakiyiaedyeglAivtwedpkeekevayLdkFav 96 
                 dlqkelftdsgagt+irrG kv+ ++sl+e++dl +Lk+++ +++   ++k +v++Y++ lk++++k+y++e++++lA+v+   p++++ +a+L +F++
  EEA22669.1 334 DLQKELFTDSGAGTMIRRGNKVHIKSSLSEFEDLAALKDVLIRDReglDAKATVDRYVEGLKDRPFKAYFDEPMDALAVVL---PQQDSAFAHLATFTI 429
                 79*******************************************9999*******************************6...588999********* PP

                 XHHHHHTTHHHHHHHHHHHHXSSEEEEEETTXTTHHHHHHCXSEEEEETTEEEEEESXXXHHHHHHHHHHHHC CS
         NAT  97 lkssqgsgvsdvvfkalkkdfpkLvWrsrednpvnkWyfersdGslkksqwvlfWyGlkdlkeveelvesfkd 169
                 +k++++++v+d+vf+++kkdfpkLvW++++d+++++W+f+++dGsl++++ vlfWyGl+d +ev++lv +f++
  EEA22669.1 430 TKAGWLTNVADNVFTSIKKDFPKLVWTVKADDENLTWFFDKADGSLSRDGDVLFWYGLEDGDEVKQLVLEFTK 502
                 ********************************************************************99986 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.0   0.0   4.5e-33   1.4e-29       1     119 [.     581     703 ..     581     705 .. 0.94

  Alignments for each domain:
  == domain 1  score: 103.0 bits;  conditional E-value: 4.5e-33
                     EEEEETTTSHHHHHHHHHHHCTSSEEEEEEEESTTTTTSBHHHHSGGGTTTECEBEEE.GGGGGCTT-SEEEE-SCHHHHHHHHHHH...HHTTS CS
  Semialdhyde_dh   1 kvaivGatGyvGqellrlLeehpevelvvllsssrsaGkklaeavkaleegkdlkved.vdeeelkevdivflalpagvskelapkl...aeagv 91 
                     kva++Ga+Gy+Gq+l++l+++hp+++l +++s++  aGkkl+ + k    +++l+ +d   +++  ++d++++alp+gv+k++++++   a++g 
      EEA22669.1 581 KVALIGARGYTGQALINLINSHPNMDLRHVSSREL-AGKKLEGYDKREIIYENLSPDDvRRMASNGDIDCWVMALPNGVCKPFVDAVdqgADKGG 674
                     7****************************999999.**********************7777777*********************988899999 PP

                     EEEESSSTTTTSTTSEBE-HHH.HGGGGG CS
  Semialdhyde_dh  92 kviDlssdfRlkddavyvlpev.nreaik 119
                      ++Dls+d+R+++ ++y+lpe+ nr++i+
      EEA22669.1 675 LIVDLSADYRFDPSWTYGLPELvNRSTIA 703
                     *********************86888887 PP

>> Rad21_Rec8_N  N terminus of Rad21 / Rec8 like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.7   0.0   7.9e-33   2.4e-29       1      95 [.     906    1005 ..     906    1018 .. 0.88

  Alignments for each domain:
  == domain 1  score: 101.7 bits;  conditional E-value: 7.9e-33
  Rad21_Rec8_N    1 MfysqellskkgplakvWlaAtl.ek....klskkeilevniekaveeIlnpeaplaLrlsgqLllGvvriyskkvkyllsDceealekikkafk 90  
                    Mf    l s+++++a+vWl+Atl +k    k+++k+il+v++++a+++I++peap+aLrl+g+Ll+Gv+++ys+++ y l+D++ +l+k+k+a+k
    EEA22669.1  906 MFNMAFLTSQRHGVATVWLVATLgHKssskKINRKAILNVDVPRACDTIMSPEAPMALRLQGNLLYGVTKVYSRQCVYALADVQAMLDKMKTALK 1000
                    6666666777*************8889999***************************************************************99 PP

  Rad21_Rec8_N   91 sikea 95  
                     ++ +
    EEA22669.1 1001 IVHGR 1005
                    76533 PP

>> AA_kinase  Amino acid kinase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.1   0.0     4e-31   1.2e-27       3     229 ..     101     317 ..      99     324 .. 0.94

  Alignments for each domain:
  == domain 1  score: 97.1 bits;  conditional E-value: 4e-31
                 EEEEE-TTCCCCTCCHHHHHHHHHHHHHHHHTTEEEEEE--HHHHHHHHHHTCCCCCHHHC....E..HHHHHHHHHHHHHHHHHHHHHHHHHTTHGEE CS
   AA_kinase   3 vVvKlGGssltdkeeaslrrlaeqiaalkesgnklvvVhGggsftdgllalksglssgelaaglrstleeagevatrdalaslgerlvaallaaglpav 101
                  V+K+GG+++t  e   l+ l   +a l+  g  +vvVhG+g++ +++l+  +g+++++++ g+r+t+ +++ +a+  + +  + +lv++l + g++a+
  EEA22669.1 101 AVIKVGGAIIT--EH--LQTLSSALAFLNHVGLYPVVVHGAGPQLNKMLED-AGVEPHFED-GIRVTDGKTLALAR-KLFLEENLKLVEELENMGVRAR 192
                 7**********..44..77788888888888999*****************.*********.***********999.********************** PP

                 EE-GGGTCEECCCE...HHHTTTCEEECCHHHHHHHTT-EEEEESEEEEETTTEEEEE-HHHHHHHHHHHCTSSEEEEEESSSSCESSTTTTCCTTCEC CS
   AA_kinase 102 glsaaaldateagr.degsdgnvesvdaeaieelleagvvpvltgfigldeegelgrgssDtiaallAealgAdkliiltdVdGVydadpkkvpdarll 199
                 +++   + a   ++ +++ +g++ svd++ ie  +eag +p+lt ++  ++eg+++++++D++a  lA al++ k+++l +  G+++ d      ++++
  EEA22669.1 193 PITTGVFSADYLDKeKYNLVGKINSVDKKPIEAAIEAGCLPILTSMA-ETPEGQVLNVNADVAAGELARALQPLKIVYLAEKGGLFNGDT-----GEKI 285
                 **********9999*******************************97.99999*99********************************96.....467* PP

                 CEEEHHHCHH..CSSS.TTTHHHHCHHHHHHH CS
   AA_kinase 200 peisvdeaee..saselatgGmkvkhpaalaa 229
                 + i+ de  +   ++ +++ G++ k++++ ++
  EEA22669.1 286 SVINLDEEYDhlMTQWWVRHGTRLKIKEMKEL 317
                 ******99999999***********9998776 PP

>> Rad21_Rec8  Conserved region of Rad21 / Rec8 like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   1.9e-05     0.056       6      42 ..    1541    1578 ..    1537    1579 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 1.9e-05
                  TT-----.-----HHHHHHHHHHHHHHHHTSEEEEESS CS
  Rad21_Rec8    6 dslsllp.agktRkeAArlFyelLvLatkgvIkvkQea 42  
                  +++ llp a ++R +A ++  ++L L tk+vI+v Q +
  EEA22669.1 1541 TFSELLPpASTSRAVATQALLHVLDLTTKDVIQVLQGK 1578
                  678888878999**********************9975 PP

>> DapB_N  Dihydrodipicolinate reductase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   4.5e-05      0.14       2      43 ..     581     624 ..     580     649 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 4.5e-05
                 EEEEETTTSHHHHHHHHHHHHSTTEEEEEEEETTC..STTTTTB CS
      DapB_N   2 kvavvGasGrmGkevvkaveeaedlelvaavdrke..selegkd 43 
                 kva++Ga+G  G+++++++++++++ l  + +r+   ++leg d
  EEA22669.1 581 KVALIGARGYTGQALINLINSHPNMDLRHVSSRELagKKLEGYD 624
                 8**************************99988865334555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1599 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       487  (0.0271627); expected 358.6 (0.02)
Passed bias filter:                      457  (0.0254894); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.97u 0.32s 00:00:01.29 Elapsed: 00:00:00.53
# Mc/sec: 9042.08
//
Query:       EEA22670.1  [L=133]
Description: SNARE protein Snc2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.4e-34  116.1   0.9    5.5e-34  115.8   0.9    1.0  1  Synaptobrevin  Synaptobrevin
  ------ inclusion threshold ------
       0.07   13.8   0.0       0.12   13.0   0.0    1.4  1  AKNA           AT-hook-containing transcription factor
       0.15   10.0   0.0       0.19    9.6   0.0    1.0  1  Prominin       Prominin


Domain annotation for each model (and alignments):
>> Synaptobrevin  Synaptobrevin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.8   0.9   9.3e-38   5.5e-34       2      86 ..      30     114 ..      29     116 .. 0.97

  Alignments for each domain:
  == domain 1  score: 115.8 bits;  conditional E-value: 9.3e-38
                    XXHHHHHHHHHHCCCCHHCCHHHHCHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHTXXXXXXXXXXXXXXXXXXXXX CS
  Synaptobrevin   2 ndklakikaevdevkdimkeNidkvlergekldeLvdktenLqssaqqFkkqarklkrkmwwknmkliiililvvlililiiiiv 86 
                    n+++a+++a++d+++++m+eNi+kv +rge+ld+L+dkt+nL+ saq F++ a++++++mwwk+mk++++l++vv+ili++i+++
     EEA22670.1  30 NQRTAALQAQIDDTVGVMRENINKVSQRGERLDSLQDKTDNLAVSAQGFRRGANRVRKQMWWKDMKMRVCLVIVVIILIIVIVVP 114
                    78999******************************************************************************97 PP

>> AKNA  AT-hook-containing transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0     2e-05      0.12      45      73 ..      51      79 ..      31      88 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 2e-05
        AKNA 45 eaeIyqlgqrleeLkdqtdqlkqkveefs 73
                  +++q g+rl+ L+d+td+l    + f+
  EEA22670.1 51 INKVSQRGERLDSLQDKTDNLAVSAQGFR 79
                5799****************988888776 PP

>> Prominin  Prominin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.0   3.2e-05      0.19     356     434 ..      32     110 ..      29     119 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 3.2e-05
    Prominin 356 qtaevvpdlkkalakgreqikklakkiprealdavisdlenterssktfddvvekyekyrwl..iglivcsllllivvili 434
                  ta + +++  ++   re+i+k++++   e+ld++ ++ +n+  s + f +  +++ k+ w   + + vc+++++i++i +
  EEA22670.1  32 RTAALQAQIDDTVGVMRENINKVSQRG--ERLDSLQDKTDNLAVSAQGFRRGANRVRKQMWWkdMKMRVCLVIVVIILIIV 110
                 5777778889999999********999..8888888888888888888888888888775541244555555555444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (133 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1116  (0.0622455); expected 358.6 (0.02)
Passed bias filter:                      832  (0.0464053); expected 358.6 (0.02)
Passed Vit filter:                       123  (0.00686039); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.31s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 866.82
//
Query:       EEA22671.1  [L=122]
Description: SNARE protein Snc2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.4e-34  116.5   1.7    3.8e-34  116.3   1.7    1.0  1  Synaptobrevin  Synaptobrevin
  ------ inclusion threshold ------
      0.058   14.0   0.0      0.098   13.3   0.0    1.4  1  AKNA           AT-hook-containing transcription factor


Domain annotation for each model (and alignments):
>> Synaptobrevin  Synaptobrevin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.3   1.7   4.2e-38   3.8e-34       2      88 ..      30     116 ..      29     117 .. 0.97

  Alignments for each domain:
  == domain 1  score: 116.3 bits;  conditional E-value: 4.2e-38
                    XXHHHHHHHHHHCCCCHHCCHHHHCHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHTXXXXXXXXXXXXXXXXXXXXXXX CS
  Synaptobrevin   2 ndklakikaevdevkdimkeNidkvlergekldeLvdktenLqssaqqFkkqarklkrkmwwknmkliiililvvlililiiiivic 88 
                    n+++a+++a++d+++++m+eNi+kv +rge+ld+L+dkt+nL+ saq F++ a++++++mwwk+mk++++l++vv+ili++i+++++
     EEA22671.1  30 NQRTAALQAQIDDTVGVMRENINKVSQRGERLDSLQDKTDNLAVSAQGFRRGANRVRKQMWWKDMKMRVCLVIVVIILIIVIVVPAV 116
                    78999******************************************************************************9876 PP

>> AKNA  AT-hook-containing transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0   1.1e-05     0.098      45      73 ..      51      79 ..      29      88 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 1.1e-05
        AKNA 45 eaeIyqlgqrleeLkdqtdqlkqkveefs 73
                  +++q g+rl+ L+d+td+l    + f+
  EEA22671.1 51 INKVSQRGERLDSLQDKTDNLAVSAQGFR 79
                5799****************988888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (122 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1546  (0.086229); expected 358.6 (0.02)
Passed bias filter:                      946  (0.0527637); expected 358.6 (0.02)
Passed Vit filter:                       122  (0.00680462); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.27s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 893.16
//
Query:       EEA22672.1  [L=237]
Description: short-chain dehydrogenase/reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.5e-31  107.3   0.0    4.6e-29  101.3   0.0    2.0  1  adh_short     short chain dehydrogenase
    2.7e-19   69.7   0.0    6.9e-19   68.3   0.0    1.7  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
     0.0021   18.0   0.2       0.21   11.5   0.2    2.2  1  KR            KR domain


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  101.3   0.0   7.7e-33   4.6e-29       2     193 ..       5     179 ..       4     181 .. 0.90

  Alignments for each domain:
  == domain 1  score: 101.3 bits;  conditional E-value: 7.7e-33
                 EEEEESTTSHHHHHHHHHHHHT..T-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---S.S--SSGGGCS CS
   adh_short   2 vvlvtGassGIGraiakelake..GakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGi.tgsgpfsels 97 
                 + +vtGas+GIG+a +k l+++    +vvv++rs e l++++++                  ++  ++v+ a k +g+l  Lv N G   ++g+++e +
  EEA22672.1   5 TFIVTGASRGIGLASSKYLLTApqSHNVVVIARSVELLQKLKDQY-----------------AKQVEAVDLALKSFGHLGGLVLNHGGlGQVGNIAEAD 86 
                 569***************988611567888999988776655554.................4456789999***********99887799******** PP

                 HHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHHCTH CS
   adh_short  98 eeewervievNltgvflltravlpamlkqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakelrek 193
                  e+w++ +++N+ +++  ++a+lp  l++ +GrIv++s  a+  ++ g+  Y AsKaa+++l+ +la e  +  ++ +a+ PGlvdT+m++e+re+
  EEA22672.1  87 PEQWKKRLDLNFISLVAFVKAALPP-LREPKGRIVFTSPGASVSAFRGWGLYDASKAAMNHLALTLAAEEPD--VTSVAIDPGLVDTEMQREIRED 179
                 *************************.67****************************************9877..9*****************9987 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.3   0.0   1.2e-22   6.9e-19      58     224 ..      54     224 ..      10     230 .. 0.84

  Alignments for each domain:
  == domain 1  score: 68.3 bits;  conditional E-value: 1.2e-22
                   HHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHHHHHHHHTHHHHHHHHHHHH.HCTSCCEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHH CS
  adh_short_C2  58 alveevvekfgklDilvnnagiapklkgpfletsreefdraldvnlyslfllakaalp.lmkeggsivnlssvgaervvpnynaygaaKaalealtr 153
                   ++v+ + ++fg+l +lv n g   +  g+++e++ e++++ ld n+ sl++++kaalp l +++g+iv +s  ++  ++ +   y a+Kaa+++l+ 
    EEA22672.1  54 EAVDLALKSFGHLGGLVLNHGGLGQ-VGNIAEADPEQWKKRLDLNFISLVAFVKAALPpLREPKGRIVFTSPGASVSAFRGWGLYDASKAAMNHLAL 149
                   6789999*****************9.********************************888888********************************* PP

                   HHHHHHGGGTEEEEEEEE--BHCTGGGGSTT......HHHHHHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--S CS
  adh_short_C2 154 ylAvelgpkgiRvNavspgpikTlaasgikg......fdelleelearaplgrlgtpeevaeaalfLasdeasyitG 224
                   +lA+e  +  ++  a+ pg+++T+++++i++       +++   +   +  g+l +pe+ +++++  + d+ +  tG
    EEA22672.1 150 TLAAEEPD--VTSVAIDPGLVDTEMQREIREdlvttmDPQFHLLFTTVHKDGQLLKPEQPGHVIARAVIDAPKSLTG 224
                   ****9666..*******************975544333344444555555666666666666666555555555555 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.5   0.2   3.5e-05      0.21       2      56 ..       5      54 ..       4     168 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 3.5e-05
                EEEEETTTSHHHHHHHHHHHHHH.S-EEEEE-SS..--HHHHHHHHHHHHTT-.EEE CS
          KR  2 tylitGGlGgLGlelarwlaekg.arhlvllsRsaaadedskaliaelealga.eve 56
                t+++tG+  g+Gl+ ++ l+     +++v+++Rs        +l+++l+++ a +ve
  EEA22672.1  5 TFIVTGASRGIGLASSKYLLTAPqSHNVVVIARSV-------ELLQKLKDQYAkQVE 54
                6899*************999887578899999994.......355555554221333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (237 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       453  (0.0252663); expected 358.6 (0.02)
Passed bias filter:                      437  (0.0243739); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.47u 0.24s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 1740.18
//
Query:       EEA22673.1  [L=434]
Description: extracellular exo-polygalacturonase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.1e-47  160.8  14.0    5.9e-47  160.3  14.0    1.2  1  Glyco_hydro_28  Glycosyl hydrolases family 28


Domain annotation for each model (and alignments):
>> Glyco_hydro_28  Glycosyl hydrolases family 28
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  160.3  14.0   3.3e-51   5.9e-47      60     321 ..     140     425 ..      85     432 .. 0.85

  Alignments for each domain:
  == domain 1  score: 160.3 bits;  conditional E-value: 3.3e-51
  Glyco_hydro_28  60 tvlgisGkgtidGqGqawwdgkgkkkkegkkkpkflvikkvknskiknlniknspvfhfsvesgkdltisditidasagd....hNtDgidvgss 150
                     + ++i+G+gtidG+Gq+w d  +   +   + p ++ i  ++  +i  l++  sp     v ++++++++ + i   +++    +NtDg d  +s
      EEA22673.1 140 EDVNIYGGGTIDGNGQVWYDMFAV--NATLQRPILMGIIGLEGGSIGPLKLRHSPSWYHIVANSSNVVFDGLDISGYSTSvhvaKNTDGWDTYRS 232
                     456899*****************8..888999***********************99888999****************9*9************* PP

  Glyco_hydro_28 151 kgvtisntnikngDDciainsgsknisitnvtcggGHGlSiGSvggrsd..ntVknvtvkdskvknsenGvRIKtik.............gatgt 230
                     +++ i+n++i+ngDDc++ ++ s ni ++n +c+g HG+S+GS+g++    + V+n+ v +  + n++ G RIK +              g  g+
      EEA22673.1 233 DNIVIQNSVINNGDDCVSFKPNSTNILVQNLHCNGSHGISVGSLGQYPGevDIVENILVYNISMFNASDGARIKVWPginseleaslqggGGQGS 327
                     **********************************************9665689**********************9877778877777777889* PP

  Glyco_hydro_28 231 vsnvkyeniklknvaypividqdYenkep..tgkptsgvkisdvtfkn...vtgtvksaeavkllcekgskcsdvtmsdvkitg..gkstskckn 318
                     v nv+y  + ++nv   i + q Y ++++  + + +s+++i+d+ fkn   vt+t k+++   l c++ + csd+  +++++ +  g +++ c+n
      EEA22673.1 328 VRNVTYDTMSIHNVDWAIELTQCYGQSNQtlCDEYPSKLTITDIHFKNfsgVTSTKKGKNIATLVCSSPNVCSDIYAENINVVSpsGYNQAICTN 422
                     ************************986661155569*********9984446667777788899*******************986799****** PP

  Glyco_hydro_28 319 vks 321
                     v  
      EEA22673.1 423 VDD 425
                     984 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (434 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       355  (0.0198003); expected 358.6 (0.02)
Passed bias filter:                      249  (0.0138881); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.25s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 2980.33
//
Query:       EEA22674.1  [L=298]
Description: short chain dehydrogenase/reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-39  135.6   0.5    1.7e-39  135.3   0.5    1.1  1  adh_short     short chain dehydrogenase
    5.7e-32  111.1   0.2    7.8e-32  110.7   0.2    1.1  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
    2.4e-08   34.1   0.0    4.7e-08   33.2   0.0    1.4  1  KR            KR domain
  ------ inclusion threshold ------
      0.045   13.5   0.1       0.15   11.9   0.1    1.9  1  ACT_7         ACT domain
      0.053   13.0   0.6       0.11   11.9   0.5    1.7  1  Epimerase     NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  135.3   0.5   4.9e-43   1.7e-39       1     190 [.       8     216 ..       8     221 .. 0.90

  Alignments for each domain:
  == domain 1  score: 135.3 bits;  conditional E-value: 4.9e-43
                 SEEEEESTTSHHHHHHHHHHHHTT-......EEEEEESCHHHHHHHHHHHHHT.....TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS CS
   adh_short   1 kvvlvtGassGIGraiakelakeGa......kvvvvdrseekleevakelkee.....gakalaiqvDvtdreevealvekavkklgkldvLvnNAGit 88 
                 kv +vtG++sGIG+ i + l++++       +++++d+++e+ + v+++l++e     +a++ + q+Dv+++e+  a++++++++ g++d +v+NAGit
  EEA22674.1   8 KVFIVTGGASGIGLGITRYLITQQHptltptHIAIFDINAETGNSVVSSLQQEykstsSATISFHQCDVSSWESQAAAFKEVAQQQGRVDYVVANAGIT 106
                 789*******************9853333337888****************999876667799***********************************6 PP

                 --SSG..GGCSHHH.HHHHHHHHTHHHHHHHHHHHHHHH.....HCTTEEEEEEEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE CS
   adh_short  89 gsgpf..selseee.wervievNltgvflltravlpaml.....kqssGrIvnvsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaP 179
                 ++g+   +e + ++ + ++++vNl+gv+  t++++ ++      ++ +G I+ ++S+ag +p+++ ++Y+++K++v+gl+rsla+ la +gi++na+aP
  EEA22674.1 107 EKGDLleKEAEPSKpVLATLNVNLVGVVYSTKLAVHYIRkngstSSTKGGIICTASNAGIYPFPMAPMYATTKHGVVGLVRSLARPLALEGIQINALAP 205
                 6665511566777789999******************8889988899**************************************************** PP

                 SSBSSHHHHHH CS
   adh_short 180 GlvdTdmakel 190
                 ++++T++a +l
  EEA22674.1 206 AVIETNIASSL 216
                 ******99876 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.7   0.2   2.2e-35   7.8e-32       1     188 [.      14     222 ..      14     231 .. 0.88

  Alignments for each domain:
  == domain 1  score: 110.7 bits;  conditional E-value: 2.2e-35
                   TTTTSHHHHHHHHHHHTT......-EEEEEESSGGH.HHHHHHHHHHTTSE..E....EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCS CS
  adh_short_C2   1 GaasgIGraiAkalaeeG......aevvltdlneea.kkrveelaeelgae..v....lecDVtdeeqvealveevvekfgklDilvnnagiapklk 84 
                   G asgIG +i + l  +        ++++ d+n e  ++ v +l++e++++  +     +cDV++ e+ +a+++ev+++ g++D++v nagi++k  
    EEA22674.1  14 GGASGIGLGITRYLITQQhptltpTHIAIFDINAETgNSVVSSLQQEYKSTssAtisfHQCDVSSWESQAAAFKEVAQQQGRVDYVVANAGITEK-- 108
                   55899999999999888733333358**********9**********995544245889************************************.. PP

                   S-GGGH...-HHHHHHHHHHHTHHHHHHHHHHHHHCTSC.......CEEEEEEEGGGTSBSTTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE CS
  adh_short_C2  85 gpflet...sreefdraldvnlyslfllakaalplmkeg.......gsivnlssvgaervvpnynaygaaKaalealtrylAvelgpkgiRvNavsp 171
                   g++le    + + +  +l+vnl ++++ +k a+++++++       g i++++s ++   +p   +y+++K+++++l+r+lA+ l+ +gi++Na +p
    EEA22674.1 109 GDLLEKeaePSKPVLATLNVNLVGVVYSTKLAVHYIRKNgstsstkGGIICTASNAGIYPFPMAPMYATTKHGVVGLVRSLARPLALEGIQINALAP 205
                   888886222456788999****************77766588888888************************************************* PP

                   --BHCTGGGGSTTHHHH CS
  adh_short_C2 172 gpikTlaasgikgfdel 188
                    +i+T++as+++ f+++
    EEA22674.1 206 AVIETNIASSLDLFKNM 222
                   **********9988876 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.2   0.0   1.3e-11   4.7e-08       2     110 ..       9     124 ..       8     126 .. 0.80

  Alignments for each domain:
  == domain 1  score: 33.2 bits;  conditional E-value: 1.3e-11
                 EEEEETTTSHHHHHHHHHHHHHHS.....-EEEEE-SS...--HHHHHHHHHHHHT.T-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE------ CS
          KR   2 tylitGGlGgLGlelarwlaekga.....rhlvllsRsa.aadedskaliaeleal.gaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlr 93 
                 ++++tGG+ g+Gl ++r l+ +       +h++++  +a + ++  ++l +e +++  a++++ ++Dvs+ ++ +a+++e+ ++++++  v+  Ag+++
  EEA22674.1   9 VFIVTGGASGIGLGITRYLITQQHptltpTHIAIFDINAeTGNSVVSSLQQEYKSTsSATISFHQCDVSSWESQAAAFKEVAQQQGRVDYVVANAGITE 107
                 579*****************976611111455555555433344444555666665588**************************************** PP

                 ---TTT--HHHHHHHHT CS
          KR  94 dklleemtaedleqvla 110
                 ++ l e++ae  + vla
  EEA22674.1 108 KGDLLEKEAEPSKPVLA 124
                 ********999888876 PP

>> ACT_7  ACT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.1   4.1e-05      0.15      19      42 ..     181     204 ..     176     212 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 4.1e-05
                 SS--HHHHHHHHHHTTT---EEEE CS
       ACT_7  19 dvtGivaklaspLaeagIsifqiS 42 
                 +v+G v +la+pLa +gI+i++++
  EEA22674.1 181 GVVGLVRSLARPLALEGIQINALA 204
                 599******************986 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.5   3.1e-05      0.11       2     102 ..      11     134 ..      10     203 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 3.1e-05
                 EEETTTSHHHHHHHHHHHHCTSEEEEEES-S.TTTTCHHCHHC................EEEE--TT-HH....HHHHHHHHH.T-SEEEE--S---HH CS
   Epimerase   2 lVtGatGfiGsalvkallekgyevigldrls.sasntarledl................elveldltdrs....alerlfkee.qpdavihlAavggva 78 
                 +VtG++  iG  ++++l ++++  ++ ++    + n +  + +                +++++d+   +    a++++ +++ ++d+v+  A++   +
  EEA22674.1  11 IVTGGASGIGLGITRYLITQQHPTLTPTHIAiFDINAETGNSVvsslqqeykstssatiSFHQCDVSSWEsqaaAFKEVAQQQgRVDYVVANAGITEKG 109
                 799999999*******9999988777777631333433333338899999999999999********99955556666666677899999999977777 PP

                 HHHHSHHHHHH.HHTHHHHHHHHHH CS
   Epimerase  79 assedpadfie.knlqgtlnlleaa 102
                 +  e+ a+  +   + +++nl+ ++
  EEA22674.1 110 DLLEKEAEPSKpVLATLNVNLVGVV 134
                 6666665544434444555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (298 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       495  (0.0276089); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.46
# Mc/sec: 1945.65
//
Query:       EEA22675.1  [L=692]
Description: C2H2 finger domain protein (Zms1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.9e-08   31.8   1.9    1.3e-07   30.9   1.9    1.4  1  Fungal_trans  Fungal specific transcription factor domain
    1.7e-07   31.3  10.5    1.7e-07   31.3  10.5    3.3  2  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
    6.1e-05   23.3  13.1      0.003   17.9   5.3    3.7  2  zf-C2H2       Zinc finger, C2H2 type
    0.00037   20.8   2.7    0.00037   20.8   2.7    4.0  4  zf-H2C2_2     Zinc-finger double domain
  ------ inclusion threshold ------
      0.022   15.6   3.4      0.022   15.6   3.4    4.3  5  zf-C2H2_4     C2H2-type zinc finger


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.9   1.9   3.7e-11   1.3e-07       2     190 ..     310     503 ..     309     522 .. 0.78

  Alignments for each domain:
  == domain 1  score: 30.9 bits;  conditional E-value: 3.7e-11
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltses.....qefiafplraeili............. 80 
                   +++f ++h  +++lh psf+ +               ll+a++ +Ga +s++e     + +  +      +            +             
    EEA22675.1 310 SLYFLYWHINCQLLHPPSFNIEQ----------VTMPLLAAVVFMGAMYSNEEREAYVARRMIDFaelyvF------------Stdvfssehevsct 384
                   79*********************..........***************99998866533333333333330............23333477777778 PP

  Fungal_trans  81 ......hedfsspssslwilqsLlllelyektssdralher....hhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktia 167
                          e  ++  ++++ lq+   + +   + +++++  r     ++ +v  ar++ L r++   ++    +lw+  +e+r R+  ++  lD+ ++
    EEA22675.1 385 fvgrpsTETERKDWTHFQNLQAGYVMVVTQYWAGSKTARNRameaRFNEVVLTARRMDLTRCQHLPEDRIHETLWIQ-KECRIRTMNFIALLDCAFS 480
                   8884444455555666666665555555555555444444455569999999***********9999888*******.******************* PP

  Fungal_trans 168 lklGrppllddsqinlpLPcddd 190
                   ++ + p  l  s++++ LPc+++
    EEA22675.1 481 FYSNFPCRLTPSELECDLPCEES 503
                   *******77***********987 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.7     0.036   1.3e+02       2      21 ..      39      61 ..      38      65 .. 0.82
   2 !   31.3  10.5   4.6e-11   1.7e-07       1      38 [.      79     114 ..      79     116 .. 0.93

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.036
                S-HHHHHCT---ST...SSSS-H CS
     Zn_clus  2 aCdnCrkkKvKCda...kkPaCs 21
                +C+ C     +Cd    + P C+
  EEA22675.1 39 SCIFCNEAFARCDNlrdHYPDCA 61
                9************9777777675 PP

  == domain 2  score: 31.3 bits;  conditional E-value: 4.6e-11
                 SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCC CS
     Zn_clus   1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfysessk 38 
                 haC++C + K +Cd++ P Cs+C+k+nl C  ++ + k
  EEA22675.1  79 HACESCTSMKLRCDGQSP-CSSCVKRNLACN-NTGKHK 114
                 8*****************.***********9.887766 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   5.3   8.4e-07     0.003       1      23 []      10      32 ..      10      32 .. 0.98
   2 !    7.9   0.9    0.0012       4.5       1      19 [.      38      56 ..      38      57 .. 0.90

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 8.4e-07
                EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCpdCgksFkrksnLkrHirtH 23
                ++C++C + F+r ++LkrH  +H
  EEA22675.1 10 FRCNICQRGFTRIDHLKRHHLRH 32
                89*******************99 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0012
                EEETTTTEEESSHHHHHHH CS
     zf-C2H2  1 ykCpdCgksFkrksnLkrH 19
                y C  C++ F r +nL+ H
  EEA22675.1 38 YSCIFCNEAFARCDNLRDH 56
                67778************** PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.1      0.19   6.9e+02      13      25 ..       8      20 ..       1      21 [. 0.79
   2 !   20.8   2.7     1e-07   0.00037       1      25 [.      24      48 ..      24      49 .. 0.94
   3 ?    0.3   0.0      0.32   1.1e+03      11      21 ..      75      85 ..      71      87 .. 0.79
   4 ?   -3.8   0.3         5   1.8e+04      13      20 ..     492     500 ..     491     503 .. 0.69

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.19
   zf-H2C2_2 13 kpyeCplCdkaFk 25
                k + C  C   F+
  EEA22675.1  8 KNFRCNICQRGFT 20
                569******9998 PP

  == domain 2  score: 20.8 bits;  conditional E-value: 1e-07
   zf-H2C2_2  1 nLrrHirkHtgekpyeCplCdkaFk 25
                +L+rH   H g kpy C +C+ aF+
  EEA22675.1 24 HLKRHHLRHSGVKPYSCIFCNEAFA 48
                799*********************8 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.32
   zf-H2C2_2 11 gekpyeCplCd 21
                g +++ C++C 
  EEA22675.1 75 GRRRHACESCT 85
                6678******6 PP

  == domain 4  score: -3.8 bits;  conditional E-value: 5
   zf-H2C2_2  13 kpyeCpl.C 20 
                 +++eC+l C
  EEA22675.1 492 SELECDLpC 500
                 568999647 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.6   3.4   6.1e-06     0.022       1      23 [.      10      32 ..      10      33 .. 0.94
   2 ?   10.8   0.6   0.00021      0.76       1      19 [.      38      56 ..      38      58 .. 0.95
   3 ?   -3.4   0.9         5   1.8e+04       2       7 ..      80      85 ..      79      91 .. 0.75
   4 ?   -2.5   0.9       3.8   1.4e+04       2      15 ..      96     110 ..      96     115 .. 0.67
   5 ?   -4.1   0.7         5   1.8e+04       3      13 ..     496     507 ..     495     511 .. 0.53

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 6.1e-06
   zf-C2H2_4  1 fkCpiCgksFsskkaLlrHlkth 23
                f+C iC++ F++ ++L+rH ++h
  EEA22675.1 10 FRCNICQRGFTRIDHLKRHHLRH 32
                89****************99999 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00021
   zf-C2H2_4  1 fkCpiCgksFsskkaLlrH 19
                + C +C++ F ++++L++H
  EEA22675.1 38 YSCIFCNEAFARCDNLRDH 56
                78***************** PP

  == domain 3  score: -3.4 bits;  conditional E-value: 5
   zf-C2H2_4  2 kCpiCg 7 
                 C+ C+
  EEA22675.1 80 ACESCT 85
                799993 PP

  == domain 4  score: -2.5 bits;  conditional E-value: 3.8
   zf-C2H2_4   2 kCpiC.gksFsskka 15 
                 +C+ C +++  ++++
  EEA22675.1  96 PCSSCvKRNLACNNT 110
                 5999*7766666655 PP

  == domain 5  score: -4.1 bits;  conditional E-value: 5
   zf-C2H2_4   3 Cpi.CgksFssk 13 
                 C++ C +s  ++
  EEA22675.1 496 CDLpCEESVFNC 507
                 666674443333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (692 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       609  (0.0339673); expected 358.6 (0.02)
Passed bias filter:                      330  (0.0184059); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.61u 0.23s 00:00:00.84 Elapsed: 00:00:00.41
# Mc/sec: 5053.09
//
Query:       EEA22676.1  [L=612]
Description: flavin-binding monooxygenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.1e-14   51.3   2.3    4.6e-13   48.4   0.5    2.6  2  FMO-like       Flavin-binding monooxygenase-like
    6.9e-12   45.4   0.0    1.7e-11   44.2   0.0    1.7  1  NAD_binding_8  NAD(P)-binding Rossmann-like domain
    2.3e-07   30.7   0.0     0.0015   18.2   0.0    2.5  2  DAO            FAD dependent oxidoreductase
    2.4e-06   27.0   0.0    0.00017   20.9   0.0    2.4  2  Pyr_redox_2    Pyridine nucleotide-disulphide oxidoreductase
      3e-05   23.4   0.2     0.0017   17.6   0.0    3.0  3  K_oxygenase    L-lysine 6-monooxygenase (NADPH-requiring)
    8.2e-05   22.0   0.0     0.0017   17.7   0.0    2.7  2  Pyr_redox_3    Pyridine nucleotide-disulphide oxidoreductase
    0.00012   22.1   0.4     0.0034   17.4   0.0    2.9  3  NAD_binding_9  FAD-NAD(P)-binding
     0.0047   16.2   0.1       0.49    9.6   0.0    2.8  3  Thi4           Thi4 family


Domain annotation for each model (and alignments):
>> FMO-like  Flavin-binding monooxygenase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.4   0.5   2.1e-16   4.6e-13       3     200 ..      29     215 ..      27     240 .. 0.80
   2 ?    0.7   0.1      0.06   1.4e+02     298     334 ..     350     385 ..     344     397 .. 0.78

  Alignments for each domain:
  == domain 1  score: 48.4 bits;  conditional E-value: 2.1e-16
    FMO-like   3 kvaviGaGvsGlas.ikccle.egleptcfersddiGGlwrfkenveeGrasiyksvvsnsskemscfsdfplpedypnflhnsklleylklfakefdl 99 
                 kv v+GaG+sG+++ i+   + ++++ + +e+ ddiGG w   en   G a    s    ++ e       p  e    +   +++ +y k+ ak+++ 
  EEA22676.1  29 KVRVMGAGISGIITcIRLAQKiKNIDLAVLEKNDDIGGTWY--ENRYPGCACDIPSHTYQATFE-------PNLEWSQFYASAKEIHQYWKKVAKKYGA 118
                 899********87526665543689999************4..666677776555544444333.......32333333667889************** PP

    FMO-like 100 lkyiqfkttvcsvkkrpdfstsGqwev.vtekegkkesavfdavmvctGhhvnphlplesfpGiekfkGqyfhsrdykepevfkgkrvlviGlGnsggd 197
                 +  i +k +v++ + + + +   +w++ v  ++g    +  d  + c+G + n + p  + pG++ fkG+++h+  + e   +k+kr+ v+G G sg +
  EEA22676.1 119 MEKIYLKHKVLAAHWNDELA---RWDIkVQVSDGSVWDDWCDVFISCAGSLNNWKWP--AIPGLHDFKGKLLHTAAWDEEYDYKNKRIAVVGNGSSGIQ 212
                 ***********998877665...7**9455689999999************999998..79***********************************988 PP

    FMO-like 198 iav 200
                 +  
  EEA22676.1 213 VVP 215
                 765 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.06
    FMO-like 298 vkssvkeltetsaifedgtveedidvvifatGytfaf 334
                 +k+++  +  t +   dg  + ++dv++ atG+  ++
  EEA22676.1 350 IKTEISCIDSTGITTADGV-HREVDVIVCATGFDTTY 385
                 6777777777777777775.5679********97655 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.2   0.0   7.5e-15   1.7e-11       1      66 [.      32     100 ..      32     102 .. 0.90

  Alignments for each domain:
  == domain 1  score: 44.2 bits;  conditional E-value: 7.5e-15
                    EE--SHHHHHHHHHHHCC..TEEEEEE-SSSSSSGGG-EECETTCEECTS---E.EETTHHHHCHHHHC CS
  NAD_binding_8   1 IvGaGlsGlvaAylLaka..gfdvlllekrdrlGGraasyevpgvrvdygahif.hgsgyypnvrrllr 66 
                    + GaG+sG  ++ +La++  ++d  +lek+d++GG ++ +++pg+++d + h++ ++++++ +++++++
     EEA22676.1  32 VMGAGISGIITCIRLAQKikNIDLAVLEKNDDIGGTWYENRYPGCACDIPSHTYqATFEPNLEWSQFYA 100
                    56***************87799********************************666777777778775 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0   6.7e-07    0.0015       4     106 ..      32     147 ..      29     196 .. 0.71
   2 !   10.1   0.0   0.00019      0.43     152     232 ..     338     405 ..     329     495 .. 0.75

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 6.7e-07
                 EECTSHHHHHHHHHHHHT.T...EEEEESSSSTTSSGGGSSEEEEESSS..........STHHSTH........HHHHHHHHHHHHHHHHHHHHSSTTS CS
         DAO   4 iiGGGiiGlstAyeLarr.g...VtllekgdiagsgaSgrnsgllhsgl..........rylpeas........elarlslealeelreleeelgidid 80 
                 + G+Gi G+ t   La++ +    ++lek+d++g g+   n    ++g+          +     +        +++  ++e +++++++++++g  ++
  EEA22676.1  32 VMGAGISGIITCIRLAQKiKnidLAVLEKNDDIG-GTWYENR---YPGCacdipshtyqA-----TfepnlewsQFYASAKEIHQYWKKVAKKYGA-ME 120
                 78*************99874699***********.8888887...333322223333332.....0444456668999999999*******99996.33 PP

                 .EEEEEEEEEESSHHHHHHHHHHHHHH CS
         DAO  81 .yrrtGllslaadeeelealdkllall 106
                     + ++  a+  +el+++d++++  
  EEA22676.1 121 kIYLKHKVLAAHWNDELARWDIKVQVS 147
                 344456666666556899999887764 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 0.00019
                 HHHHHHHTT-EEEESECEEEEEEEETCEEEEEEECT.EEEEEEEEEEE--GGGHHHHHTTCTTTSEEEEEEEEEEEEEECCT CS
         DAO 152 laraaealGveilegtevtgleeedgkvwgverttp.gendaadavVnaaGawsdllgllkeldlpispvrgqvlvlkplse 232
                 +++a+ +  v++++  e+  ++      +g+  tt+ g  +++d +V a+G  ++ l   +++  p+++++g +l+  ++++
  EEA22676.1 338 YLEALTDEKVDVIKT-EISCID-----STGI--TTAdGVHREVDVIVCATGFDTTYL---PRF--PMTGRKGISLAE-KWKD 405
                 677777777888884.887773.....5788..7777877789**********9988...988..99******9998.5555 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.0   7.6e-08   0.00017       2     156 ..      29     212 ..      28     218 .. 0.69
   2 ?    3.5   0.0     0.016        36     189     239 ..     338     383 ..     316     403 .. 0.76

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 7.6e-08
                  SEEEE--SHHHHHHHHHHHH..HTS-EEEEE.........TTHCHHHCSHHHHCHHHHHHHHHHHHH.................HHHHCHHHHCCCCH CS
                  xxxxxxxxxxxxxxxxxxxx..xxxxxxxxx.........xxxxxxxxxxxxxxxxxxxxxxxxxxx.................xxxxxxxxxxxxxx RF
  Pyr_redox_2   2 dvvviGgGpAGlaaaltlaq..agakvtlve.........legtclnggcllskallgvaedaeias.................evvkklnqgielll 71 
                  +v v G+G+ G+ + ++laq  ++++ +++e          e+  ++  c +++   ++  +++  +                 +v kk+++  + +l
   EEA22676.1  29 KVRVMGAGISGIITCIRLAQkiKNIDLAVLEknddiggtwYENRYPGCACDIPSHTYQATFEPN--LewsqfyasakeihqywkKVAKKYGAMEKIYL 124
                  67899***************77799999997667766666555555555544333333333333..13568888886666666666666666666666 PP

                  CCTCEEEEESCEEEEETEEEC.............TCEEEEEESEEEE---E..EE-BCTCTTC.TTBEECCSECHHHHHHCCSS-TSEEEEES-SHHH CS
                  xxxxxxxxxxxxxxxxxxxxx.............xxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  72 geevvkidpgkkkvklekkke.............gdeekiaydklvlAtGs..sprdlgipGvaenvgklvrtldsaealklkllpkrivvvGgGyiG 154
                  +++v++   +          +             g+  +  +d  + + Gs  + + + ipG+ +  gkl++t + +e++ +k+++  i+vvG+G  G
   EEA22676.1 125 KHKVLAAHWN----------DelarwdikvqvsdGSVWDDWCDVFISCAGSlnNWKWPAIPGLHDFKGKLLHTAAWDEEYDYKNKR--IAVVGNGSSG 210
                  6555555422..........2233333333553433334445999*****97666777**********************999998..*******999 PP

                  HH CS
                  xx RF
  Pyr_redox_2 155 vE 156
                  + 
   EEA22676.1 211 IQ 212
                  86 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.016
                  HHHHHHHTTEEEEESCEEEEEEETTEEEEEEETTSCEEEESEEEE-S-EEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2 189 leealekeGvevklgtsvkeidgngeklevvledgeeidadlvvvavGvrp 239
                  + eal++e+v+v  +t++  id+ g     ++ dg   ++d +v a+G+  
   EEA22676.1 338 YLEALTDEKVDVI-KTEISCIDSTG----ITTADGVHREVDVIVCATGFDT 383
                  6788888899988.88887787776....5888888889999999999865 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0     0.095   2.1e+02     187     223 ..      23      59 ..      11      65 .. 0.82
   2 !   17.6   0.0   7.6e-07    0.0017      88     251 ..      95     266 ..      85     282 .. 0.71
   3 ?    0.5   0.0      0.12   2.6e+02     327     341 ..     368     382 ..     346     383 .. 0.84

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.095
  K_oxygenase 187 ellakkriaVvGsGqSaaeifedllrrqkkvelklvt 223
                  +++++ ++ V+G+G S+   +  l+++ k+ +l+++ 
   EEA22676.1  23 DDARPIKVRVMGAGISGIITCIRLAQKIKNIDLAVLE 59 
                  46778899**********9999999999988887665 PP

  == domain 2  score: 17.6 bits;  conditional E-value: 7.6e-07
  K_oxygenase  88 letflpsRkefedYlrWvasqle..eqvrfgeeveevepdeeeeeelltveskdaegeeeelearnlvlgvG.....tepkiPevleklegkervvHs 178
                   ++f+ s ke ++Y + va++    e++  +++v + ++++e  +   +v++  ++g+     +   +   G     + p+iP + + ++   +++H+
   EEA22676.1  95 WSQFYASAKEIHQYWKKVAKKYGamEKIYLKHKVLAAHWNDELARWDIKVQV--SDGSVWDDWCDVFISCAGslnnwKWPAIPGLHD-FK--GKLLHT 187
                  5788999999999999999986644558889999999999987554445554..566666555554444444321124577777665.55..79**** PP

  K_oxygenase 179 seylerkeellakkriaVvGsGqSaaeifedllrrqkk.....velklvtrsealepldd...spfvneifsPeyvdyfys 251
                  +   e+   + ++kriaVvG G S+ +++  +l + ++        +++++  a e+ld+   s+  n  fsPe++ +f s
   EEA22676.1 188 AAWDEEY--DYKNKRIAVVGNGSSGIQVVPAMLPDVSHidhyaRGRTWLSSTFAREKLDEiggSNKDNITFSPERIAEFKS 266
                  **99998..899********************9996544445444556665555555554222777777899999988865 PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.12
  K_oxygenase 327 etlevdavvlATGYr 341
                     evd++v+ATG++
   EEA22676.1 368 VHREVDVIVCATGFD 382
                  56799********96 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0   7.7e-07    0.0017       2     200 ..      32     234 ..      32     244 .. 0.76
   2 ?    0.4   0.0      0.14   3.1e+02     234     270 ..     353     384 ..     335     408 .. 0.58

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 7.7e-07
  Pyr_redox_3   2 IiGaGPaGlaaaiel.kkagledylilEkg.nignsiyrypkemtfispsftsekleipdlnaiseetspafslkeeklsrkealeYlrevaksfel. 96 
                  + GaG  G+ + i l +k++  d+ +lEk+  ig ++y+ +      +   +s+  ++          +p++  ++ ++s+ke+ +Y ++vak++   
   EEA22676.1  32 VMGAGISGIITCIRLaQKIKNIDLAVLEKNdDIGGTWYENRYPGCACDI--PSHTYQA--------TFEPNLEWSQFYASAKEIHQYWKKVAKKYGAm 119
                  5799999*98887752555656999****999**999965544444442..2333222........234677778889****************9864 PP

  Pyr_redox_3  97 .piklfeeVesvkkedeg....fevetskety...eAkkviiAtGefdkPnklnipGeek...lvkhyskvkefhkyagqkvvViGgknSavDaAlel 183
                   +i l+++V + + +de      +v+ s +++    ++  i  +G  ++ +++ ipG ++   +  h++  +e  +y++++++V+G + S++ +   +
   EEA22676.1 120 eKIYLKHKVLAAHWNDELarwdIKVQVSDGSVwddWCDVFISCAGSLNNWKWPAIPGLHDfkgKLLHTAAWDEEYDYKNKRIAVVGNGSSGIQVVPAM 217
                  579********99988753434788999986623258888999***************97633445777777888****************9988888 PP

  Pyr_redox_3 184 vrkgaeVtvvtrgseie 200
                      +++  + rg ++ 
   EEA22676.1 218 LPDVSHIDHYARGRTWL 234
                  77777777777777765 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.14
  Pyr_redox_3 234 evkeikekeeeykvktedgkkvevkddvvlatGykpd 270
                  e+  i+       ++t+dg + ++ d +v atG++ +
   EEA22676.1 353 EISCIDS----TGITTADGVH-REVDVIVCATGFDTT 384
                  3333332....2456666533.333555555888765 PP

>> NAD_binding_9  FAD-NAD(P)-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.0   1.5e-06    0.0034       2      78 ..      32     104 ..      31     144 .. 0.78
   2 ?   -0.9   0.0      0.67   1.5e+03       1      16 [.     202     217 ..     202     225 .. 0.85
   3 ?    1.1   0.1      0.16   3.5e+02     120     154 ..     350     380 ..     338     382 .. 0.72

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 1.5e-06
  NAD_binding_9   2 ivGaGprGlavlerLlarakkkspleitlfdpsepgagrvwrtdqseelllNvpasemslftddpptfaeWlrerga 78 
                    + GaG++G+ ++ rL+++    +++++ + +++    g+ w++++ +     +p+++ ++  + + +  +++++ ++
     EEA22676.1  32 VMGAGISGIITCIRLAQKI---KNIDLAVLEKNDDI-GGTWYENRYPGCACDIPSHTYQATFEPNLEWSQFYASAKE 104
                    67****************5...**********9998.89*****999999999999999888777555555555443 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.67
  NAD_binding_9   1 aivGaGprGlavlerL 16 
                    a+vG G +G+ v+ ++
     EEA22676.1 202 AVVGNGSSGIQVVPAM 217
                    89********998665 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.16
  NAD_binding_9 120 hraevvdleeradgqavlladgaslaadaVvLAlG 154
                    +++e+  ++    +  +++adg + ++d +v A+G
     EEA22676.1 350 IKTEISCID----STGITTADGVHREVDVIVCATG 380
                    444444444....345889***************9 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.6   0.0   0.00022      0.49      19      58 ..      29      68 ..      19      72 .. 0.87
   2 ?    2.8   0.0     0.025        57       8      31 ..     189     212 ..     183     219 .. 0.83
   3 ?   -1.3   0.0      0.48   1.1e+03     148     171 ..     353     384 ..     344     405 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00022
                EEEEE--SHHHHHHHHHHHHC.TTS-EEEEESSSS--TTTT CS
        Thi4 19 DvvivGaGssGLtaayylakk.pdlkvailersvspGGGaw 58
                 v ++GaG sG+ +   la+k  ++ +a+le++  +GG  w
  EEA22676.1 29 KVRVMGAGISGIITCIRLAQKiKNIDLAVLEKNDDIGGT-W 68
                5789********99999**9999**********999874.4 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.025
                 HHHHHHHHTEEEEEEE--SHHHHH CS
        Thi4   8 yfedllkyaesDvvivGaGssGLt 31 
                 + ++  +y +  +++vG GssG+ 
  EEA22676.1 189 AWDEEYDYKNKRIAVVGNGSSGIQ 212
                 567778999*************86 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.48
                 TSS.-B-EEEEEE........EEEE--GSSST CS
        Thi4 148 tqscvDPlvirak........vvvdatGhdge 171
                 + sc+D   i ++        v+v atG d+ 
  EEA22676.1 353 EISCIDSTGITTAdgvhrevdVIVCATGFDTT 384
                 56788888887777888888899999999975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (612 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       885  (0.0493614); expected 358.6 (0.02)
Passed bias filter:                      619  (0.0345251); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.71u 0.31s 00:00:01.02 Elapsed: 00:00:00.46
# Mc/sec: 3997.70
//
Query:       EEA22677.1  [L=556]
Description: benzoate 4-monooxygenase cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.7e-53  180.1   0.0    9.2e-53  179.6   0.0    1.1  1  p450         Cytochrome P450
  ------ inclusion threshold ------
      0.087   12.8   0.0       0.21   11.6   0.0    1.6  1  Consortin_C  Consortin C-terminus


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  179.6   0.0     1e-56   9.2e-53      19     443 ..      83     524 ..      67     539 .. 0.84

  Alignments for each domain:
  == domain 1  score: 179.6 bits;  conditional E-value: 1e-56
                 TCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHH..HHHHHHHHHTSHSTT.TH CS
        p450  19 keelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkk..lRrfltptltsfgkl.sl 114
                 +++ h v+ +l++kyg+++r+ ++   +  +s+p+++k ++++k+  ++++++ ++ a +++ + + +++ ++ e+w+   +R +++    ++ +  s 
  EEA22677.1  83 SGQAHLVHADLHRKYGSVVRIGPN---TLSISDPSLIKTIYNTKNPWKKSHMYAVQEAVLPDGTPQPNLFSTTDERWHAkmMRPISLYLSSNK-SVlST 177
                 689999**************9875...6789**************99999998888898999999999999999***8622555555555544.556** PP

                 HHHHHHHHHHHHHHHHCCCCHCS.EEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHHHHHHHHHHHHHHHHHCHHHHCCCCCHHHTCCSC.HHHHHHHH CS
        p450 115 eelveeeaedlveklrkkagess.elditellskaaldvigsilFgarfdlledeklselvkaveelssllskssvqllllfpllkylpt.kllrklke 211
                 e++++++++ l++ l++k    +  +di++++ ++  d++g+++Fg+ ++ l+ + l++ +++ ++  + +   +++ +++++l  yl t ++ r++++
  EEA22677.1 178 EKFLDSSINLLIDVLKEKFVNTAlPCDIADVFIRFSWDAMGYTTFGSALGFLDGS-LKNSEELLKDSDRDF-DYFTRTCQMPWLHYYLKTnWIARRFNA 274
                 ****************99888888**************************65555.778888888888888.556678887775555544155566653 PP

                 ..HHHHHHHHHHHHHHHHH.HCHCHC....SCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHH CS
        p450 212 ..avkklkdlldklieerr.etldsa....kksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklreEi 303
                    + +++  l+++++ ++ ++l+++    + ++ dfld  l+a+ +k  +  ++d ++   +l+ ++aG++ t+ tl+ + y+ +k+  v +k+r E+
  EEA22677.1 275 pqLQWAVDLSLENYFKRQQmRQLSDKkkpvSIEEQDFLDKYLEAQ-QKYPQ-LIDDYQMIGYLLTNTVAGSHPTAYTLTAMVYYVLKTNGVLAKIRAEL 371
                 1122334444555544333134444489998899**********8.44444.8********************************************** PP

                 HHHC..CTTTT-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS.CEEETT.EEE-TT-EEEEEHHHHHT-TTTS.SSTTS--GGGGB-TTS.... CS
        p450 304 devl..gdkreptyddlqklpyldavikEtLRlhpvvplllpRevtk.dvvirg.ylipkGtevivnlyalhrdpevf.pnPeeFdpeRFldekg.... 393
                 +++   g +++++y+d ++l yl+avi+E+ R+hp   l l+Rev++  +++++ +++  Gt+v + ++ ++r++evf p+ ++F peR+l+  g    
  EEA22677.1 372 ESASlyGCNEPVSYKDAKNLLYLEAVIREAIRIHPGFALVLEREVPEgGLHLPDgRFVTSGTVVGMDAWVINRNEEVFgPETDSFIPERWLQLCGesid 470
                 *997689999*************************************99999999*************************************999999* PP

                 ....CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSG CS
        p450 394 ....nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpetdp 443
                     + ++     l FG+G R+C+G+ lA +el    a+++ nF+v+l + +++
  EEA22677.1 471 hfhvRRQKMFNTVLSFGTGTRSCLGQSLALVELYKTAASFFANFDVQLVDPKQE 524
                 9988666777889*********************************98654443 PP

>> Consortin_C  Consortin C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   2.4e-05      0.21      54      95 ..      35      76 ..      21      90 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 2.4e-05
  Consortin_C 54 dscllllllclvtvvisvGGtalycalgdvessvctdfaknv 95
                 d  l +lll lvt+++ +  t ++ ++     + ct f++  
   EEA22677.1 35 DIILCFLLLTLVTLFLKLAQTYFFSSVKSFPGPFCTKFTDSW 76
                 5678899*******************************9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (556 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       472  (0.0263261); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.25s 00:00:00.83 Elapsed: 00:00:00.41
# Mc/sec: 4061.03
//
Query:       EEA22678.1  [L=379]
Description: hypothetical protein PMAA_092980 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.1e-35  123.6   0.3      1e-18   67.8   0.0    2.2  2  DDE_Tnp_1_7  Transposase IS4


Domain annotation for each model (and alignments):
>> DDE_Tnp_1_7  Transposase IS4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.0   0.1   8.8e-19   1.6e-14       2      67 ..      69     143 ..      68     151 .. 0.94
   2 !   67.8   0.0   5.8e-23     1e-18     151     310 ..     177     348 ..     164     369 .. 0.82

  Alignments for each domain:
  == domain 1  score: 54.0 bits;  conditional E-value: 8.8e-19
  DDE_Tnp_1_7   2 pvelFelflpdkilerivkatNayakqk.........kkwleltaeElkaFlGllllmglvrlpsvedyWstkdf 67 
                  p+++F+lf+++++++ +++ tN+ya  k         ++w+ +t  ElkaF+G+++ mg  + p+++dyW+++++
   EEA22678.1  69 PYQIFSLFFTEDLFKVLADNTNMYAYAKlsknmnphhRNWRSTTPGELKAFVGAQIYMGFTKEPQLKDYWDEEKH 143
                  9**********************************************************************9963 PP

  == domain 2  score: 67.8 bits;  conditional E-value: 5.8e-23
  DDE_Tnp_1_7 151 prkvgiklhvlcdsqtgyilalelyegearnlrl..srelgktnalvlrLleplqgkg..rvvvmdnfftslellqeLakkgtyavGtlkknrsglPk 244
                    + g+k++vl+d   gy + +++  ++++ ++    +el+kt ++v +L+++l + +  + +++dn+fts++l+++L++ ++ a+Gt +  ++++P+
   EEA22678.1 177 IERQGFKIFVLAD--HGYCYYFYPASRTKGVVEVgmAKELTKTGQMVYELVQTLPKDNktYDLYLDNYFTSVNLFKALREIQVGACGTTRP-HKEFPN 271
                  4678*********..9**********999877653378****************965555*******************************.77***8 PP

  DDE_Tnp_1_7 245 eltqklpkgellaryg......gplmllkwndrkkvkllstyss....qklveskersgqki.karpklvedYnqal 310
                   l++ ++ g+   +++      +++  ++w d++ v+ l+t+++    ++ +e+ +r+ qk+    p +++++ ++ 
   EEA22678.1 272 LLKKLKDLGSYIPYHKvcaipvNDVLCVAWQDNNIVLALTTIHTvdqtDDYIERTRRRPQKTsTNGPLVHKEFGEQA 348
                  8876666666666666666666**********************887666699999999998667888888877665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (379 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       472  (0.0263261); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.41
# Mc/sec: 2768.52
//
Query:       EEA22679.1  [L=247]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.1e-07   31.9  15.8     0.0014   19.0   4.8    2.8  2  zf-C2H2      Zinc finger, C2H2 type
    0.00018   21.8  14.0    0.00054   20.3   1.6    3.4  3  zf-H2C2_2    Zinc-finger double domain
     0.0047   17.7  14.4       0.38   11.7   2.7    2.9  2  zf-C2H2_4    C2H2-type zinc finger
  ------ inclusion threshold ------
       0.15   12.2   2.3        8.6    6.6   0.3    2.3  2  Zn-ribbon_8  Zinc ribbon domain
          3    7.9  11.8        1.1    9.4   3.1    2.7  2  zf-BED       BED zinc finger
        4.5    5.8  16.7        4.9    5.7  16.7    1.2  1  Hamartin     Hamartin protein
        5.3    7.6   9.1       0.88   10.0   2.4    2.8  3  zf-met       Zinc-finger of C2H2 type


Domain annotation for each model (and alignments):
>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.0   4.8   5.3e-07    0.0014       1      23 []     184     206 ..     184     206 .. 0.95
   2 !   18.0   3.2   1.1e-06    0.0029       1      23 []     212     237 ..     212     237 .. 0.96

  Alignments for each domain:
  == domain 1  score: 19.0 bits;  conditional E-value: 5.3e-07
                 EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirtH 23 
                 y+C  C+k F+r+s+L+ H  +H
  EEA22679.1 184 YVCRTCHKAFSRPSSLRIHSHSH 206
                 9******************8887 PP

  == domain 2  score: 18.0 bits;  conditional E-value: 1.1e-06
                 EEET..TTTEEESSHHHHHHHHHC.C CS
     zf-C2H2   1 ykCp..dCgksFkrksnLkrHirt.H 23 
                 ++C+  +Cgk F+ +sn+krH r  H
  EEA22679.1 212 FRCThaGCGKAFSVRSNMKRHERGcH 237
                 89*******************99888 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.9   0.7    0.0018       4.5      14      25 ..     183     194 ..     164     195 .. 0.81
   2 !   20.3   1.6   2.1e-07   0.00054       2      25 ..     199     224 ..     198     224 .. 0.91
   3 ?    0.9   0.3      0.28   7.2e+02       1      11 [.     228     239 ..     228     240 .. 0.79

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0018
   zf-H2C2_2  14 pyeCplCdkaFk 25 
                 +y C  C+kaF+
  EEA22679.1 183 RYVCRTCHKAFS 194
                 59*********8 PP

  == domain 2  score: 20.3 bits;  conditional E-value: 2.1e-07
   zf-H2C2_2   2 LrrHirkHtgekpyeCp..lCdkaFk 25 
                 Lr H  +Htgekp+ C    C+kaF+
  EEA22679.1 199 LRIHSHSHTGEKPFRCThaGCGKAFS 224
                 88999************977****95 PP

  == domain 3  score: 0.9 bits;  conditional E-value: 0.28
   zf-H2C2_2   1 nLrrHirk.Htg 11 
                 n +rH r  H g
  EEA22679.1 228 NMKRHERGcHSG 239
                 689***955987 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.7   4.0   0.00032      0.81       1      23 [.     184     206 ..     184     207 .. 0.94
   2 !   11.7   2.7   0.00015      0.38       1      24 []     212     237 ..     212     237 .. 0.93

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00032
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlkth 23 
                 + C+ C+k Fs++++L+ H  +h
  EEA22679.1 184 YVCRTCHKAFSRPSSLRIHSHSH 206
                 89*****************9888 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 0.00015
   zf-C2H2_4   1 fkCpi..CgksFsskkaLlrHlkthH 24 
                 f+C++  Cgk Fs +++++rH +  H
  EEA22679.1 212 FRCTHagCGKAFSVRSNMKRHERGCH 237
                 89**********99999****99877 PP

>> Zn-ribbon_8  Zinc ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   0.1     0.009        23       6      16 ..     184     194 ..     183     210 .. 0.80
   2 ?    6.6   0.3    0.0034       8.6       6      29 ..     212     236 ..     211     243 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.009
  Zn-ribbon_8   6 YrCeeCghefe 16 
                  Y C+ C++ f 
   EEA22679.1 184 YVCRTCHKAFS 194
                  9*******998 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0034
  Zn-ribbon_8   6 YrCee..Cghefevlqsisdaplta.C 29 
                  +rC+   Cg+ f v+  +++ +    C
   EEA22679.1 212 FRCTHagCGKAFSVRSNMKRHE--RgC 236
                  8999999********9999533..335 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.4   3.1   0.00042       1.1       7      34 ..     168     198 ..     160     206 .. 0.73
   2 ?    1.6   2.9      0.11   2.9e+02      18      43 ..     213     237 ..     202     238 .. 0.77

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00042
                 S----......GGSS--EETTTTEE----SSTHH CS
      zf-BED   7 ftpvs......lkeqkavCryCgkilsrgggttn 34 
                 + p+s        + + vCr C+k +sr    + 
  EEA22679.1 168 YFPLStttsypQNHERYVCRTCHKAFSRP---SS 198
                 444446777778899************95...33 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.11
                 EETT..TTEE----SSTHHHHHHHHHS- CS
      zf-BED  18 vCry..CgkilsrgggttnLkrHLrrkH 43 
                 +C +  Cgk +s +   +n+krH r +H
  EEA22679.1 213 RCTHagCGKAFSVR---SNMKRHERGCH 237
                 566666******99...******66555 PP

>> Hamartin  Hamartin protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7  16.7    0.0019       4.9     302     405 ..      42     143 ..      25     216 .. 0.74

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.0019
    Hamartin 302 qlsslsgtspavlsvessrskddeislWSPssvcgmttppsspgivpttelelsssasllsskvsstpeaagkatpetTPakssrklppslsesavvva 400
                 +l+s    s++++s  s  s+++ +  + Ps+++ +  +p +p    + ++  s+++s+ls+ ++s++++++  t+++TP++s  ++++++ + + +++
  EEA22679.1  42 SLPSGRSHSASISSAVSHPSHQQRT--SLPSISASLQNTPIHPSERLSISSLASHDSSRLSHAIPSPSSTTASITTTATPSTSYYSTSEEKAYPRSHST 138
                 4555555555555554444444444..899999999988888855554456699*****************************9977555555555433 PP

    Hamartin 401 lpass 405
                   + +
  EEA22679.1 139 SAPVT 143
                 33332 PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.1         3   7.7e+03      12      22 ..      87      97 ..      87      98 .. 0.74
   2 ?   10.0   2.4   0.00035      0.88       1      19 [.     184     202 ..     184     206 .. 0.89
   3 ?    0.5   0.0      0.35     9e+02       6      22 ..     219     235 ..     219     235 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 3
      zf-met 12 sesqlksHlqG 22
                s s+l sH  +
  EEA22679.1 87 SISSLASHDSS 97
                56899999666 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00035
      zf-met   1 fyCelCnvtfnsesqlksH 19 
                 + C  C++ f+ +s+l+ H
  EEA22679.1 184 YVCRTCHKAFSRPSSLRIH 202
                 78***************** PP

  == domain 3  score: 0.5 bits;  conditional E-value: 0.35
      zf-met   6 CnvtfnsesqlksHlqG 22 
                 C + f+ +s++k H +G
  EEA22679.1 219 CGKAFSVRSNMKRHERG 235
                 6677777899****998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (247 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       886  (0.0494171); expected 358.6 (0.02)
Passed bias filter:                      390  (0.0217525); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.47u 0.25s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 1767.56
//
Query:       EEA22680.1  [L=477]
Description: monocarboxylate permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.8e-25   89.6  52.6    1.4e-24   86.7  39.4    2.1  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.7  39.4   7.9e-29   1.4e-24       4     335 ..     100     417 ..      93     430 .. 0.80
   2 !    8.2   7.2   5.9e-05       1.1      34      81 ..     422     469 ..     418     477 .] 0.56

  Alignments for each domain:
  == domain 1  score: 86.7 bits;  conditional E-value: 7.9e-29
       MFS_1   4 aaflsalarsilgpalplalaedlg.............ispseigllltlyalgaavaslplGrlsdr.fGrrrvlllglllfalglllllfasslw.l 87 
                 a+fl + +++i++++         g             +s+s+i+++ ++ a++ ++   ++G+l d  + +r + + g ++++lg ++l+++  +w +
  EEA22680.1 100 AHFLFFNSWGIVNTF---------GsyetyysvdllstSSASAISWIGSVQAFLLLFVGALTGPLYDAgY-ARHLTISGSFFLVLGQMMLSLCKEYWqV 188
                 445555555554444.........3333333355666789999************************966.77799999999999966666789***** PP

       MFS_1  88 llvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspke 186
                 ll+  +  G+g+g+l   + a++a++f+  + + a+g+ +ag+s+G i+ p++   l  s+g++++  ++++v l   +++++++    + r  ++   
  EEA22680.1 189 LLAQGFCIGIGCGLLCVPSTAILAQYFST-KIATAVGFTAAGSSFGGIIYPVVFHKLQPSIGFPWATRVIGFVILATQLIAIAVY----KVRILPE--- 279
                 ****************************9.*********************************************9966444444....3333332... PP

       MFS_1 187 eekgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlgls.glllaglllallalvgailallagrlsdrlgrrrrlllallll 284
                      +++++++ + a++ +p++ i++++++++f+g+++ ++++ ++     +++ +  l+ ++la++ + +a+++++ g lsd++g+   ++++++++
  EEA22680.1 280 -----KKRAIID-FAAFKEPPYV-IFVFSAFVGFMGLYQPFFYVQTF-AIEKHITdA-NLGFYILAIMNATSAFGRIIPGILSDKIGP---MNVIIPCA 366
                 .....3345777.9999999977.5999999999************9.888888852.66666677777777777**********996...88888888 PP

       MFS_1 285 llaalglallavtssavllllvlvliGfglgfvfpsllalasdlappeeag 335
                 +++a++++ + + ++a+ l+++++++Gf++g++++s +a++++l  +++a 
  EEA22680.1 367 FISAMLCLCTIAVDNAAGLIVLMAFYGFFSGTFVSSPNAIVVHLSAQNRAK 417
                 8888888888888899**************************999775554 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 5.9e-05
       MFS_1  34 igllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllf 81 
                 +g ++++ +++++++++++G++ d++G  ++++++ +l +++++++++
  EEA22680.1 422 LGQMYGVISFAMLIGTPVGGVVLDNHGYTPLWIFSGVLVGVSGAFMIL 469
                 444566666777777777777777777777666666666655333332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (477 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       861  (0.0480228); expected 358.6 (0.02)
Passed bias filter:                      430  (0.0239835); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.33s 00:00:00.96 Elapsed: 00:00:00.51
# Mc/sec: 2837.69
//
Query:       EEA22681.1  [L=514]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
     0.0014   18.5   0.0     0.0035   17.2   0.0    1.7  1  F-box-like      F-box-like
  ------ inclusion threshold ------
      0.015   15.1   0.1      0.045   13.7   0.1    1.9  1  F-box           F-box domain
       0.25   10.7   1.8        2.5    7.6   0.3    2.3  2  Enolase_like_N  Enolase N-terminal domain-like


Domain annotation for each model (and alignments):
>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   5.9e-07    0.0035       2      38 ..       5      42 ..       4      53 .. 0.86

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 5.9e-07
  F-box-like  2 srLPdEiLlqIFsyL.ppsdLlrlalVCrrWrrvaldt 38
                ++LP+E+Ll I   + + +d l+ ++++r++++++ ++
  EEA22681.1  5 DQLPTEVLLVIIGLVqSNRDFLAFSRTSRSFHNITKNE 42
                68***********886677***************9776 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.1   7.5e-06     0.045       3      46 ..       4      48 ..       2      50 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 7.5e-06
                HHHS-HHHHHHHHHTS-HHH.HHHHCTT-HHHHHHHTTHHHHHHH CS
       F-box  3 lsrLPsevlrhILerLplsd.llalrrVSkgwrilidsdrlwcks 46
                l++LP evl+ I+  +      la++r+S+++++++++  + +++
  EEA22681.1  4 LDQLPTEVLLVIIGLVQSNRdFLAFSRTSRSFHNITKNELPLRRK 48
                788999999999999866667***************998877765 PP

>> Enolase_like_N  Enolase N-terminal domain-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.1     0.023   1.4e+02       3      17 ..      42      56 ..      41      61 .. 0.87
   2 ?    7.6   0.3   0.00042       2.5      25      46 ..     484     505 ..     479     506 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.023
  Enolase_like_N  3 slPlrvrFRgitvRe 17
                    +lPlr ++R i+ +e
      EEA22681.1 42 ELPLRRKYRRIRIKE 56
                    69*********9887 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.00042
  Enolase_like_N  25 aGwgEfspFleYddaeaarWla 46 
                     +   E +p ++Y d+e+++W++
      EEA22681.1 484 EEMIERAPKVDYPDEESEPWWE 505
                     5556899*************85 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (514 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       483  (0.0269396); expected 358.6 (0.02)
Passed bias filter:                      457  (0.0254894); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.50
# Mc/sec: 3091.97
//
Query:       EEA22682.1  [L=507]
Description: benzoate 4-monooxygenase cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.3e-69  233.1   0.0    7.3e-69  232.7   0.0    1.1  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  232.7   0.0   4.1e-73   7.3e-69      11     440 ..      58     479 ..      47     496 .. 0.82

  Alignments for each domain:
  == domain 1  score: 232.7 bits;  conditional E-value: 4.1e-73
                 HCHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGH.HHHHHHHHHHHHHHTS CS
        p450  11 gnllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfang.ekwkklRrfltptlts 108
                 + + + + ++ +h+++ ++++kyg+++r  +++   v  s+pe+ k v+++++++ ++++++++        ++ +++  ++ + ++ +Rr++ +    
  EEA22682.1  58 WLVYWAR-DGSMHRKMIDMHEKYGKLVRTAPNE---VSFSNPEYLKVVYGAGSDFYKSDWYSVWQGR-----RKWDLFGERSeAIHRAQRRLVSQIYSL 147
                 4555665.799******************9987...66799***********988888877777775.....788888888867788888888888887 PP

                 HSTT.THHHHHHHHHHHHHHHHHCCCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSHH.HHHHHHHHHHHH...HHHCHHHHCCCCCHHHTCCS CS
        p450 109 fgkl.sleelveeeaedlveklrkkagesselditellskaaldvigsilFgarfdlledekl.selvkaveelss...llskssvqllllfpllkylp 202
                 + ++ +le++v+  + ++++kl++ ag+   +++t++ + +a+dvig+++F++ f+ le  ++   + +++++ ++   ++    + +     ++ + +
  EEA22682.1 148 S-NMkKLEPYVDTATTMFLNKLKDMAGKE--MNMTKWAQLYAFDVIGEVTFSKTFGFLEAGEDiHGAFTLIDNSLRsaaWVGYVPWVY-----WANVRL 238
                 7.6669***********************..**************************9999741334444444432111332222223.....444444 PP

                 CHHHHHHHHHHHHHHHHHHHHHHHHHHCHCHCSCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHH CS
        p450 203 tkllrklkeavkklkdlldklieerretldsakksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklre 301
                  ++      +  ++++ll    +  +e  ++  +++ d ld + + +  k+++ +++d  ++  v   +faG+d ts tls ++y+++knP++ ++l  
  EEA22682.1 239 APIIGNRLGVLGRQNGLLILAAKAIKERKERG-SDHQDVLDQFFQVQ--KEKP-EFDDICITSMVASNIFAGSDSTSITLSAFIYHIIKNPQYRARLVA 333
                 44444444455555555554444444444444.4569*********8..6666.8******************************************** PP

                 HHHHHCCTTT.....T-HHHHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSS.CEEETTEEE-TT-EEEEEHHHHHT-TTTS.SSTTS--GGGGB-TTS CS
        p450 302 Eidevlgdkr.....eptyddlqklpyldavikEtLRlhpvvplllpRevtk.dvvirgylipkGtevivnlyalhrdpevf.pnPeeFdpeRFldekg 393
                 Eide+ + +       + +d  +++pyl+a+++E+ R hp+v ++l R+++   v+i+g+ ip Gt+v  n++ +h+ +e f +++++F+p+R+l+e +
  EEA22682.1 334 EIDEAAKVNNvkhgeIFPMDVANNMPYLQACLHEAIRCHPAVGMNLGRVAPPqGVEIDGVYIPGGTVVGANAWVVHQHKETFgEDADKFRPDRWLEEPE 432
                 ****9844444589899********************************9754********************************************99 PP

                 CTESSCTT--TTEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTS CS
        p450 394 nskrksfaflPFGaGpRnCiGerlArmelklflatlLqnFevelqpe 440
                 + ++ + af+ FGaG R CiG+++A +el+ +  +l++ Fe+el + 
  EEA22682.1 433 RVSQMKRAFFSFGAGSRFCIGKNIAWLELSKMAPSLFHDFEIELVNP 479
                 8889***************************************8654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (507 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       527  (0.0293937); expected 358.6 (0.02)
Passed bias filter:                      488  (0.0272185); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.48
# Mc/sec: 3179.64
//
Query:       EEA22683.1  [L=656]
Description: ankyrin repeat and BTB/POZ domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.5e-24   83.8   0.0    3.4e-13   49.8   0.8    2.7  2  BTB       BTB/POZ domain
    5.5e-08   33.2   0.0    1.5e-07   31.8   0.0    1.8  1  Ank_4     Ankyrin repeats (many copies)
    2.7e-06   27.9   0.0      6e-06   26.8   0.0    1.6  1  Ank_2     Ankyrin repeats (3 copies)
    3.2e-06   27.3   0.0    9.2e-06   25.8   0.0    1.9  1  Ank_5     Ankyrin repeats (many copies)
    0.00013   22.2   0.0      0.014   15.8   0.0    2.9  2  Ank       Ankyrin repeat
  ------ inclusion threshold ------
      0.017   15.6   0.2       0.35   11.6   0.0    3.0  2  Ank_3     Ankyrin repeat
      0.064   13.5   0.1       0.14   12.4   0.1    1.5  1  DUF3342   Domain of unknown function (DUF3342)


Domain annotation for each model (and alignments):
>> BTB  BTB/POZ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.3   0.0   1.5e-10     4e-07       5     101 ..     146     248 ..     143     257 .. 0.79
   2 !   49.8   0.8   1.3e-16   3.4e-13      23     106 ..     359     442 ..     354     446 .. 0.92

  Alignments for each domain:
  == domain 1  score: 30.3 bits;  conditional E-value: 1.5e-10
                 HHHTTTS-EEEEETTTEEEEE-HHHHHHH-HHHHHHHTSTTTTTCCCEEEEETTSGHHHHHHHHHHHHHSEEEC-..........CGGGHHHHHHHHHH CS
         BTB   5 resgelcDvtlvvgdgkefkahkavLaarSpyFkalftskeieessvseielddvepeafealLefiYtgeleit..........seenleelLaaadl 93 
                 r++   +D+++  g ++++  hk++L+arSpyF++ +      +s++ +++ +   p af+a +++iY g  + +          ++e ++ + ++ ++
  EEA22683.1 146 RDHPVTWDIVVTDG-EESLFLHKFILSARSPYFQKKLAAA--PDSTSWKLP-STLPPAAFAAAIRYIYLGDSPRElragpgtgftESEVVAGVDRIGRH 240
                 66778899999999.7***********************9..566656785.9999************9987776777777777555556666666677 PP

                 HT-HHHHH CS
         BTB  94 lqiprlkk 101
                 l+ip+l +
  EEA22683.1 241 LEIPNLLD 248
                 77777666 PP

  == domain 2  score: 49.8 bits;  conditional E-value: 1.3e-16
                 EEE-HHHHHHH-HHHHHHHTSTTTTTCCCE...EEEETTSGHHHHHHHHHHHHHSEEEC-CGGGHHHHHHHHHHHT-HHHHHHHHHH CS
         BTB  23 fkahkavLaarSpyFkalftskeieessvs...eielddvepeafealLefiYtgeleitseenleelLaaadllqiprlkkaceef 106
                 +++h+a L  rS++F+a+f+s  ++e++v+   +i   d++pe++e++L+f Yt++ +++  + ++++L aadll i++lk+++  +
  EEA22683.1 359 YPVHRAML-LRSEFFNAMFSSA-FKEAQVTehlNIISVDCSPEVLEIVLRFFYTEKADFP-LDIAVDVLFAADLLFIEKLKTKAAVL 442
                 78999988.59***********.99999999999999**********************8.********************998766 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.8   0.0     6e-11   1.5e-07       5      55 .]      43      92 ..      41      92 .. 0.96

  Alignments for each domain:
  == domain 1  score: 31.8 bits;  conditional E-value: 6e-11
       Ank_4  5 LhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55
                L  a+ +g+l++++  ++ g++ina+ ++++ t+l+ A + g++e+++lLl
  EEA22683.1 43 LCEACRKGDLKVCQEKISEGVNINAR-DSYDYTPLILASLCGHFEVAQLLL 92
                567999********************.***********************8 PP

>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.0   2.3e-09     6e-06       2      73 ..      44     122 ..      20     131 .. 0.64

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 2.3e-09
       Ank_2   2 hlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh.....ad.ndgrtpLhyAarsghleivklLl 73 
                   A+++g+l++++  + eg+++n  +  + t+L++A   g+ e+++lLle       d  +g+  L++A  ++  +i +lLl
  EEA22683.1  44 CEACRKGDLKVCQEKIsEGVNINarDsYDYTPLILASLCGHFEVAQLLLESgalceRDtFQGERCLYNAL-ND--RIRNLLL 122
                 4566666666777766666666654246677777777777777777777655553333444667777776.44..5666666 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.8   0.0   3.6e-09   9.2e-06       4      49 ..      61     105 ..      59     111 .. 0.91

  Alignments for each domain:
  == domain 1  score: 25.8 bits;  conditional E-value: 3.6e-09
       Ank_5   4 hgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrG 49 
                 +g +++n++d + +tpL++A+ +g+++v++lLl+ ga +   +++G
  EEA22683.1  61 EG-VNINARDSYDYTPLILASLCGHFEVAQLLLESGALCERDTFQG 105
                 67.99****************************9999998888887 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.0     0.055   1.4e+02       9      31 ..      46      69 ..      33      70 .. 0.89
   2 !   15.8   0.0   5.4e-06     0.014       3      28 ..      73      98 ..      71     102 .. 0.88

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.055
                HHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank  9 AatngkkriiklLL.hGAnlnald 31
                A++ g++ ++++ +  G n+na+d
  EEA22683.1 46 ACRKGDLKVCQEKIsEGVNINARD 69
                88899999***99977*******9 PP

  == domain 2  score: 15.8 bits;  conditional E-value: 5.4e-06
                BBHHHHHHHHTTHHHHHHHH.TTTSTT CS
         Ank  3 nTPLHlAatngkkriiklLL.hGAnln 28
                +TPL lA+ +g+ ++++lLL +GA l 
  EEA22683.1 73 YTPLILASLCGHFEVAQLLLeSGA-LC 98
                9*******************9998.55 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.0      0.62   1.6e+03       8      30 ..      45      66 ..      43      67 .. 0.83
   2 ?   11.6   0.0   0.00014      0.35       2      27 ..      72      96 ..      71      99 .. 0.90

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.62
       Ank_3  8 lAarsgnleivkfLlenkgadvn 30
                +A+r g+l++++  +   g+++n
  EEA22683.1 45 EACRKGDLKVCQEKIS-EGVNIN 66
                69******99998888.688887 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 0.00014
       Ank_3  2 GetpLhlAarsgnleivkfLlenkga 27
                 +tpL lA ++g++e++++Lle  ga
  EEA22683.1 72 DYTPLILASLCGHFEVAQLLLE-SGA 96
                58*******************9.665 PP

>> DUF3342  Domain of unknown function (DUF3342)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   5.3e-05      0.14      27      95 ..     369     438 ..     351     440 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 5.3e-05
     DUF3342  27 mrYfeeiikryiseaqrleeid.irvnCdlsifdWLmkyvkkkkrkltpenvvsillsssfLkmeeLvde 95 
                  ++f+ + +   +eaq++e+++ i+v C  ++ + ++++   +k ++  + +v +l +++ L +e+L  +
  EEA22683.1 369 SEFFNAMFSSAFKEAQVTEHLNiISVDCSPEVLEIVLRFFYTEKADFPLDIAVDVLFAADLLFIEKLKTK 438
                 4799999*9***********98459**************************************9999765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (656 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       576  (0.0321267); expected 358.6 (0.02)
Passed bias filter:                      512  (0.0285571); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 4398.78
//
Query:       EEA22684.1  [L=731]
Description: G2-specific protein kinase NimA, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-54  185.5   0.1    2.8e-34  118.7   0.0    2.3  2  Pkinase         Protein kinase domain
    7.7e-35  120.4   0.0    5.1e-24   85.0   0.0    2.2  2  Pkinase_Tyr     Protein tyrosine kinase
  ------ inclusion threshold ------
       0.01   14.7   2.6        0.2   10.4   0.0    2.4  2  Pkinase_fungal  Fungal protein kinase
      0.041   13.2   0.0      0.079   12.3   0.0    1.4  1  Kinase-like     Kinase-like
       0.18   12.0   1.5        0.5   10.6   0.7    2.2  2  DUF3896         Protein of unknown function (DUF3896)


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.4   0.2   2.8e-21     1e-17       1     115 [.      12     132 ..      12     135 .. 0.89
   2 !  118.7   0.0   7.7e-38   2.8e-34     119     262 ..     163     294 ..     157     296 .. 0.87

  Alignments for each domain:
  == domain 1  score: 64.4 bits;  conditional E-value: 2.8e-21
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHSCTTB--EEE..EEEESSEEEEEEE--TTEBHHHHHH....HHS CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklkhpnivrlye..vfeekdelylvleyveggeladlle....rkg 93 
                 ye+lek+G GsfG + k+++k++g i + K+i+  k+++k+++++++E +il +l+hpniv +y+   ++ +++lyl +ey+ gg+l  +++    +++
  EEA22684.1  12 YEVLEKIGAGSFGIIRKVKRKSDGFILCRKEINYIKMSQKEREQLTAEFNILSSLRHPNIVAYYHreHLKASQDLYLYMEYCGGGDLGMVIKnlknTNK 110
                 7899***********************************************************972256679**************9888888863444 PP

                 S--HHHHHHHHHHHHHHHHHHH CS
     Pkinase  94 slseeeakkiakqilegleylH 115
                   +e+ + ++++q+ ++l  +H
  EEA22684.1 111 FAEEDFVWRVLAQLTTALYRCH 132
                 455556669**********999 PP

  == domain 2  score: 118.7 bits;  conditional E-value: 7.7e-38
                 EE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCSBCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHHHHHSS-STTTSSHHHHHHHHHHTHHHHH CS
     Pkinase 119 iiHrDlKpeNiLidekgelKitDFGlakelessskltsfvgtseYlAPEvlkeneyskkvDvWslGvilyelltgkppfsgekgkekvekeldqlekil 217
                 i+HrDlKpeNi++ +++ +K++DFGl+k ++s+  ++++vgt+ Y++PE+  +++y+ ++D+W+lG+i+yel  + ppf+++++ +   + +++     
  EEA22684.1 163 ILHRDLKPENIFLGSDNSVKLGDFGLSKLMQSHDFASTYVGTPFYMSPEICAAEPYTLHSDIWALGCIMYELCQKAPPFNAKTHIQ-LVQRIRE----- 255
                 99******************************************************************************433333.2222222..... PP

                 HHCTSHH...HHHTTS-HHHHHHHHHHT-SSGCCSTTHHHHHTSG CS
     Pkinase 218 kilgetkeklpeaseiseeakdllkkllkkdpkkRltaeellqhp 262
                        +  p ++  s+e+k ++ ++l+++p +R+  + ll+ p
  EEA22684.1 256 ------GKYPPLPDMYSSELKGVIASCLRVNPDQRPDTATLLNLP 294
                 ......3455667777********************999998866 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.3   0.0   8.3e-12     3e-08       3      95 ..      14     105 ..      12     132 .. 0.78
   2 !   85.0   0.0   1.4e-27   5.1e-24     123     256 ..     162     291 ..     154     293 .. 0.90

  Alignments for each domain:
  == domain 1  score: 33.3 bits;  conditional E-value: 8.3e-12
                  EEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEEST.TSSHHHHHHHHHHHHHHHTS-BTTB--EEEEEE..SSSSEEEEEE--TTEBHHHHHHHT CS
  Pkinase_Tyr   3 lgkklGeGafGkVvegtlkgekekkevkVavKtlke.eateeekeelleeakimkklkhpnivkllgvct..keepllivteyvkgGdLlkfLrkk 95 
                  + +k+G+G+fG + + + k    ++      K ++  +++++e+e+l+ e +i+++l+hpniv+++       ++ l++ +ey+ gGdL   +++ 
   EEA22684.1  14 VLEKIGAGSFGIIRKVKRK----SDGFILCRKEINYiKMSQKEREQLTAEFNILSSLRHPNIVAYYHREHlkASQDLYLYMEYCGGGDLGMVIKNL 105
                  6799***********9999....55555555666541555667899********************9877658888*************9999875 PP

  == domain 2  score: 85.0 bits;  conditional E-value: 1.4e-27
                  TEEEST-SGGGEEEEETTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSEEEHHHHHHHHHHHHHHHHTTSSGTTTTSHHHHHHHHHHT CS
  Pkinase_Tyr 123 klvHrdlaarNvLlsenkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekkftsksDvWsfGvllwEiftlgespypglkneevleklke 220
                   ++Hrdl   N++l +++ vk++DfGL++ ++++d     ++      +m+pE+  ++ +t +sD+W+ G +++E+++  + p++  ++ +++++++e
   EEA22684.1 162 MILHRDLKPENIFLGSDNSVKLGDFGLSKLMQSHDFA---STYVGTPFYMSPEICAAEPYTLHSDIWALGCIMYELCQ-KAPPFNAKTHIQLVQRIRE 255
                  689**************************99444443...34445567*****************************9.789**************** PP

                  TEES-BBTTSBHHHHHHHHHHT-SSGGGS--HHHHH CS
  Pkinase_Tyr 221 gkrlekpekcpeelyelmkkcweedpeeRptfselv 256
                  gk  + p+  ++el+ ++ +c++ +p++Rp+ ++l+
   EEA22684.1 256 GKYPPLPDMYSSELKGVIASCLRVNPDQRPDTATLL 291
                  ******************************988875 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   5.6e-05       0.2     325     402 ..     160     232 ..     153     237 .. 0.84
   2 ?    0.7   3.6     0.049   1.7e+02     184     248 ..     313     404 ..     302     463 .. 0.59

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 5.6e-05
  Pkinase_fungal 325 kagiLHrDiSenNilitdskkegerkglLiDLDlakelsddssesgarertGTleFmaievlkgee...HsyrhDLESffy 402
                     ++ iLHrD   +Ni +      ++++  L D+ l k ++    ++ a + +GT+ +m+ e+  +e    Hs  + L  ++y
      EEA22684.1 160 QIMILHRDLKPENIFLG-----SDNSVKLGDFGLSKLMQS---HDFASTYVGTPFYMSPEICAAEPytlHSDIWALGCIMY 232
                     678**************.....78999********99994...5666789***********99766677888777777766 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.049
  Pkinase_fungal 184 rksEaelLkkaeergvegvarlvahedveekdddi.aeiRkgldvtkaekfrskrkvvsssssqe.............................l 248
                     +++E+  L+k +e +   +a + +++ +    +di a +R++++v+ + +++++ ++  +  s++                              
      EEA22684.1 313 KRREESALQKTKELE-IKMANYEKDKALI--REDIdATLRREWEVKARLEIERQVQMRYEELSKQfetevrarvaaeldkvnktrapppesiqpR 404
                     568889999995544.5699999999986..77777999*****999954444444333333333455555555555444444443333333332 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   2.2e-05     0.079     165     251 ..     163     242 ..     157     264 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 2.2e-05
  Kinase-like 165 lvhgkftvdnllldekgglmlggft..aLvragtkvvlseve.kgfaPpEllgsrggytrknktkmthkldaWqlGlviyriwclklPlt 251
                  ++h +++++n++l  +  ++lg+f+  +L++  + +    v    +  pE++++           +t   d W+lG  +y +     P++
   EEA22684.1 163 ILHRDLKPENIFLGSDNSVKLGDFGlsKLMQSHDFAS-TYVGtPFYMSPEICAA---------EPYTLHSDIWALGCIMYELCQKAPPFN 242
                  79********************996225666555555.3344355899****99.........358999********9999854444554 PP

>> DUF3896  Protein of unknown function (DUF3896)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.7   0.00014       0.5      21      42 ..      38      60 ..      29      79 .. 0.84
   2 ?   -3.2   0.0       2.8   9.9e+03      28      38 ..     296     306 ..     292     308 .. 0.77

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00014
     DUF3896 21 lCkk.lssltlskkereqlklei 42
                lC+k ++ +++s+kereql  e 
  EEA22684.1 38 LCRKeINYIKMSQKEREQLTAEF 60
                89775899***********9986 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.8
     DUF3896  28 ltlskkereql 38 
                 + l +kere +
  EEA22684.1 296 VRLVRKEREVV 306
                 67999***965 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (731 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       837  (0.0466841); expected 358.6 (0.02)
Passed bias filter:                      383  (0.021362); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.42
# Mc/sec: 5229.56
//
Query:       EEA22685.1  [L=298]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-21   75.5  14.1    3.1e-21   75.5  14.1    2.7  3  Wbp11     WW domain binding protein 11
  ------ inclusion threshold ------
        3.3    8.0   5.1         25    5.2   5.1    2.3  1  DUF3040   Protein of unknown function (DUF3040)


Domain annotation for each model (and alignments):
>> Wbp11  WW domain binding protein 11
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.5  14.1   3.5e-25   3.1e-21       1      78 []       6      84 ..       6      84 .. 0.99
   2 ?   -0.4   0.5      0.17   1.5e+03      35      47 ..     261     273 ..     231     277 .. 0.62
   3 ?    1.1   1.2      0.06   5.4e+02      35      60 ..     261     286 ..     249     294 .. 0.70

  Alignments for each domain:
  == domain 1  score: 75.5 bits;  conditional E-value: 3.5e-25
       Wbp11  1 gKslnPadaaRKaqrkkelkKnKkerqkareaklakkdpdeleeeiekLeelessg.kldaadkkklekLekelkavkk 78
                ++s+nPa+a+RK +++k+lkK+K+e  ++r++kla+++p++++++i++L+ +e+sg  l++++k+ le+Le++l+av+k
  EEA22685.1  6 ERSINPAQAQRKLEKQKALKKGKAEAVARRNEKLARRNPERIQRQINDLKGIEESGqPLRPREKQILEELERDLRAVQK 84
                79******************************************************9********************97 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.17
       Wbp11  35 akkdpdeleeeie 47 
                 + +dp+e+ + ie
  EEA22685.1 261 EEEDPEEILRRIE 273
                 4456666666665 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.06
       Wbp11  35 akkdpdeleeeiekLeelessgklda 60 
                 + +dp+e+ + ie+ ++++ss+k  +
  EEA22685.1 261 EEEDPEEILRRIEEETRAQSSNKKHT 286
                 67899999999998776666665444 PP

>> DUF3040  Protein of unknown function (DUF3040)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   5.1    0.0028        25       2      20 ..      63      81 ..      63     118 .. 0.79

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.0028
     DUF3040  2 pLsehEqrvLeeiEraLaa 20
                pL  +E+++Lee+Er+L+a
  EEA22685.1 63 PLRPREKQILEELERDLRA 81
                7999*************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (298 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1392  (0.0776396); expected 358.6 (0.02)
Passed bias filter:                      453  (0.0252663); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2000.10
//
Query:       EEA22686.1  [L=168]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
     0.0028   16.6   0.3     0.0038   16.2   0.3    1.1  1  Cobalamin_bind   Eukaryotic cobalamin-binding protein
  ------ inclusion threshold ------
       0.01   15.9   1.4      0.041   13.9   1.4    1.8  1  DUF1664          Protein of unknown function (DUF1664)
      0.031   13.9   1.5       0.37   10.5   0.4    2.6  2  Nbl1_Borealin_N  Nbl1 / Borealin N terminal
      0.045   13.1   1.7      0.047   13.0   1.7    1.1  1  DUF4407          Domain of unknown function (DUF4407)
      0.063   13.8   0.1      0.088   13.4   0.1    1.3  1  POX              Associated with HOX
      0.063   13.1   1.3        1.1    9.1   1.2    2.3  1  CdvA             CdvA-like coiled-coil domain
       0.23   11.6   1.2       0.43   10.7   1.2    1.4  1  Fib_alpha        Fibrinogen alpha/beta chain family
       0.25   11.4   4.5       0.65   10.0   1.0    2.3  3  Baculo_PEP_C     Baculovirus polyhedron envelope protein, PEP


Domain annotation for each model (and alignments):
>> Cobalamin_bind  Eukaryotic cobalamin-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.3   1.7e-06    0.0038      77     132 ..      52     109 ..      46     115 .. 0.83

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.7e-06
                     HHHHS-SSS--HHHHHHHHHHHHHTT----H..HHHHHHHHHHHHHHHHHHHHHTTTS CS
  Cobalamin_bind  77 qekllsslssstGqLALyilALkssCedlde..ekserlvsqLkkkleeekenieesh 132
                     +++ ++s+ ss G+L L  ++L++  ++l+   e+ ++++++L+ ++++ ++n+ ++ 
      EEA22686.1  52 SSSRATSAASSQGRLLLDPMSLRALSHQLEYlqEQIHHRIEHLEDQMQASIQNSRDRA 109
                     33334555558*******************998999****************997766 PP

>> DUF1664  Protein of unknown function (DUF1664)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   1.4   1.8e-05     0.041      43     119 ..      84     163 ..      70     167 .. 0.59

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.8e-05
     DUF1664  43 vesvskqleqvseslaatkrhLssridrvdkkldeqkeiskeikeevtevredls...eigedvesvkeavegleskler 119
                  e++ +++e++ ++++a  ++  +r  +v ++ d+ ++ +++i + +++++++l+   +i++ v+s ++ +e+ +++l++
  EEA22686.1  84 QEQIHHRIEHLEDQMQASIQNSRDRAGNVIRNADAEIARTRAILAAIDDLENELAkigHIRDIVKSFRARIESYDHRLDQ 163
                 45555556665555555555555555555555555555555555555555554441115667788888888888888765 PP

>> Nbl1_Borealin_N  Nbl1 / Borealin N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.4   0.00016      0.37       6      34 ..      80     108 ..      76     113 .. 0.90
   2 ?    1.6   0.0     0.096   2.2e+02       5      25 ..     129     155 ..     126     167 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00016
  Nbl1_Borealin_N   6 LenfdlEveeRirrlraelelllktlrnr 34 
                      Le ++ ++++Ri+ l+ +++  +++ r r
       EEA22686.1  80 LEYLQEQIHHRIEHLEDQMQASIQNSRDR 108
                      788999*******************9977 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.096
  Nbl1_Borealin_N   5 lLenfdlE......veeRirrlraele 25 
                       ++++++E      + + ++ +ra  e
       EEA22686.1 129 AIDDLENElakighIRDIVKSFRARIE 155
                      577888887777666666666666655 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   1.7   2.1e-05     0.047     143     237 ..      59     165 ..      10     168 .] 0.73

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 2.1e-05
     DUF4407 143 a...............alqaeidaaearldalraeaqkeldgtkgtgttgvaGkgpaakekkaqldaaqaelaelkakldatarlaalraelaeleaer 226
                 a               al+ +++ +++++    ++++++++   ++    + + g + ++++a++++ +a la++++  ++ a++ + r+  ++ +a++
  EEA22686.1  59 AassqgrllldpmslrALSHQLEYLQEQIHHRIEHLEDQMQASIQNS---RDRAGNVIRNADAEIARTRAILAAIDDLENELAKIGHIRDIVKSFRARI 154
                 03333334444444559999999999999999999999999876666...7889999999999999999999998888778888888888888888888 PP

     DUF4407 227 akeraasqaaa 237
                 ++   + ++aa
  EEA22686.1 155 ESYDHRLDQAA 165
                 88777777765 PP

>> POX  Associated with HOX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.1   3.9e-05     0.088      47     102 ..      49     103 ..      19     124 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 3.9e-05
         POX  47 egegsssssssass...saelssaerqelqrkkakLlsmldeVdrrYrqYldqmqavvs 102
                 ++++ss ++    s   s+     + + l++   +L ++++++++r ++  dqmqa ++
  EEA22686.1  49 NSNSSSRAT----SaasSQGRLLLDPMSLRALSHQLEYLQEQIHHRIEHLEDQMQASIQ 103
                 222222222....13334444489999****************************9765 PP

>> CdvA  CdvA-like coiled-coil domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   1.2   0.00049       1.1      30      58 ..      72     100 ..      70     159 .. 0.87

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00049
        CdvA  30 alkklkekakelkeklkkrlkeledqiks 58 
                 +l++l  + + l+e++++r++ ledq+++
  EEA22686.1  72 SLRALSHQLEYLQEQIHHRIEHLEDQMQA 100
                 58899999999***************975 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   1.2   0.00019      0.43      45     125 ..      78     161 ..      71     167 .. 0.65

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00019
                 CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHHHHHHHHHCCCHHHHHHHCCH...HHHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  45 eeisnstkeaeelvkeikdslrekqkskkdn.dnvikksskeleeeilrlketidaqe...snirvLqnvlesneqkiqkLeqdi 125
                 ++++  ++++++ +++++d++++  ++++d   nvi++   e+  +   + + id+ e    +i  ++++++s + +i+      
  EEA22686.1  78 HQLEYLQEQIHHRIEHLEDQMQASIQNSRDRaGNVIRNADAEIA-RTRAILAAIDDLEnelAKIGHIRDIVKSFRARIESYDHRL 161
                 45556667788888888888887777766666888888888888.5555555565433113677778888888888887655555 PP

>> Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.3         4     9e+03       5      16 ..      26      37 ..      22      37 .. 0.78
   2 ?   10.0   1.0   0.00029      0.65      49      97 ..      75     123 ..      70     140 .. 0.45
   3 ?    5.2   0.1    0.0093        21      34      75 ..     124     164 ..     111     167 .. 0.70

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 4
  Baculo_PEP_C  5 qqLnggggnqfl 16
                  qq+ + gg++++
    EEA22686.1 26 QQIALQGGGGHV 37
                  899999999886 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00029
  Baculo_PEP_C  49 alsedlksllaeldtrldtlltnLtdalnalqdtlrneLtnlnsiltnL 97 
                   als++l+ l +++++r+++l +++++++++  d   n + n +++++  
    EEA22686.1  75 ALSHQLEYLQEQIHHRIEHLEDQMQASIQNSRDRAGNVIRNADAEIART 123
                   4445555555555555555555555555555555555555544444432 PP

  == domain 3  score: 5.2 bits;  conditional E-value: 0.0093
  Baculo_PEP_C  34 aqlatlldaietqLnalsedlksllaeldtrldtlltnLtda 75 
                    ++ +++d++e++L ++ + +++ ++++++r+++  ++L++a
    EEA22686.1 124 RAILAAIDDLENELAKIGH-IRDIVKSFRARIESYDHRLDQA 164
                   4566777888888888766.8888888888888887777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (168 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1613  (0.089966); expected 358.6 (0.02)
Passed bias filter:                      893  (0.0498076); expected 358.6 (0.02)
Passed Vit filter:                        94  (0.0052429); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.51u 0.29s 00:00:00.80 Elapsed: 00:00:00.45
# Mc/sec: 1124.62
//
Query:       EEA22687.1  [L=217]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.3e-22   78.6   1.3    5.1e-22   78.0   1.3    1.3  1  Rpr2      RNAse P Rpr2/Rpp21/SNM1 subunit domain
  ------ inclusion threshold ------
       0.15   12.1   2.5        0.3   11.1   2.5    1.5  1  NECFESHC  SH3 terminal domain of 2nd SH3 on Neutrophil cytoso


Domain annotation for each model (and alignments):
>> Rpr2  RNAse P Rpr2/Rpp21/SNM1 subunit domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.0   1.3   5.7e-26   5.1e-22       1      90 []      64     183 ..      64     183 .. 0.96

  Alignments for each domain:
  == domain 1  score: 78.0 bits;  conditional E-value: 5.7e-26
                 HHHHHHHHHH.................................HHHHH-HHHHHHHHHHHHHHHHHCT---SSTCCCTB-TTT--B--CTTTEEEEEE- CS
        Rpr2   1 rlnfLyqaahl................................qlaeaspalsrylakqlrevskkaqlrlppsvkrtvCkkCgsvlipgvtcsvrven 67 
                 r+ +L++aa +                                ++++ + ++ r++++q+r+++ k+q rl+++ kr +Ck+C+ +l+pg t++ +++n
  EEA22687.1  64 RMAYLHRAAIYlqthpksetntptqnpddikhgdrekdsearqAKSNIQATMPRQYITQMRSIALKTQQRLSQETKRGFCKRCDLLLVPGETSTEEIQN 162
                 89***************************************98788888999**********************************************9 PP

                 SSS-E.........EEEEETTTT CS
        Rpr2  68 kskkkkkkkkkadvlvvtClaCg 90 
                 +sk+   +k++advlvv+C+aC+
  EEA22687.1 163 ESKG--CRKPWADVLVVRCKACE 183
                 8887..78**************5 PP

>> NECFESHC  SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   2.5   3.3e-05       0.3       4      45 ..     102     140 ..      97     145 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 3.3e-05
    NECFESHC   4 ekleaarsqlkkrkaPPRRStirNAkSIHkksRkrlSQdtYR 45 
                 +++ +a+s+++  +  PR   i   +SI  k  +rlSQ+t R
  EEA22687.1 102 SEARQAKSNIQ--ATMPRQY-ITQMRSIALKTQQRLSQETKR 140
                 44556666666..5556665.*******************87 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (217 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       790  (0.0440627); expected 358.6 (0.02)
Passed bias filter:                      426  (0.0237604); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.24s 00:00:00.68 Elapsed: 00:00:00.40
# Mc/sec: 1632.79
//
Query:       EEA22688.1  [L=349]
Description: ATP dependent RNA helicase (Sub2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.1e-34  118.8   0.0    4.2e-34  117.8   0.0    1.5  1  DEAD        DEAD/DEAH box helicase
    5.4e-27   94.3   0.1    2.9e-24   85.5   0.1    2.6  3  Helicase_C  Helicase conserved C-terminal domain
    1.8e-08   34.6   0.0    4.4e-08   33.3   0.0    1.6  1  ResIII      Type III restriction enzyme, res subunit
     0.0006   19.2   0.1     0.0045   16.4   0.0    2.1  2  CMS1        U3-containing 90S pre-ribosomal complex subunit


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.8   0.0   9.3e-38   4.2e-34      15     173 ..       4     158 ..       1     161 [. 0.93

  Alignments for each domain:
  == domain 1  score: 117.8 bits;  conditional E-value: 9.3e-38
                 CEEEEEESTTSSHHHHHHHHHHHHHHHSTTSTS-EEEEEESSHHHHHHHHHHHHHHTTT.STSEEEEEETTSSHHHHHHHHHTT...CSEEEEEHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxx RF
        DEAD  15 gdvlvaaeTGsGKTlaflipvlqivyetkgktgpkalivePtreLaeqtlnnlkkfkky.idlrvlliiggvaardqlskldng...vdivvgtpgrld 109
                  d+l++a+ G GKT++f++  l+ + +   + + ++l+++ treLa q+ n++ +f ky  ++++ +++gg++ +++++ l+n+   ++ivvgtpgrl 
  EEA22688.1   4 SDLLCQAKSGLGKTAVFVLTTLHGL-D-PVEGEVQVLVMCHTRELAYQIKNEYARFSKYlPQVKTAVFYGGTPMQKDIELLSNKetrPNIVVGTPGRLN 100
                 699*******************888.3.7999***************************55699999**************765678************ PP

                 HHHHCTSSHCTTEEEEEEETHHHHHHT.TTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD 110 dllstgklnlsqvrflVlDEadrlldq.gfsdfinrilnqlpqitcdgklqrqvivlSATlpkdv 173
                  l++++kl+l++v+ +VlDE+d++ldq ++++++++i++++       ++++qv+++SATl+++v
  EEA22688.1 101 ALVRDKKLSLRNVKAFVLDECDKMLDQiDMRRDVQEIFRNT-------PAEKQVMMFSATLSQEV 158
                 ***************************99*******99999.......56678********9887 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.1   0.0    0.0031        14      15      71 ..      33      93 ..      20      96 .. 0.71
   2 ?   -2.9   0.0         2   8.8e+03      12      27 ..     140     155 ..     124     171 .. 0.58
   3 !   85.5   0.1   6.5e-28   2.9e-24       2     111 .]     197     305 ..     196     305 .. 0.91

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0031
                TTSEEEEEESSHHHHHH..HHHHHHHT...TSTEEEESTTSTHHHHHHHHHHHHTTSSSEEE CS
  Helicase_C 15 eggkilifvntidrlek..vklllekk...gikvavlhgelpqnereeileqfnkgesdvLi 71
                 + ++l++++t++ +++   ++ + +k   ++k+av++g +p ++ +e l++  + + ++++
  EEA22688.1 33 GEVQVLVMCHTRELAYQikNEYARFSKylpQVKTAVFYGGTPMQKDIELLSNK-ETRPNIVV 93
                56799********666555334322225669***********99999998876.33444555 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 2
                 HTTTTSEEEEEESSHH CS
  Helicase_C  12 leeeggkilifvntid 27 
                 ++  ++++++f+ t +
  EEA22688.1 140 NTPAEKQVMMFSATLS 155
                 3344555555555544 PP

  == domain 3  score: 85.5 bits;  conditional E-value: 6.5e-28
                 HHHHHHHHHHHTTTTSEEEEEESSHHHHHH.HHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSSHHH CS
  Helicase_C   2 kleallellkleeeggkilifvntidrlek.vklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprnvts 99 
                 k ++l ell  + e ++++ifv+++ r+++  kll ++ ++ ++++h+  +q+er++  ++f++ + ++ +atdv +rGidi+++nl in+dlp + +s
  EEA22688.1 197 KNRKLSELL-DNLEFNQVIIFVKSTLRANElDKLL-RECNFPSIAVHSGVSQEERIKRYKEFKEFNKRICVATDVFGRGIDIERINLAINYDLPGDADS 293
                 778899999.8999************888744555.4447***********************99999******************************* PP

                 HHHHHTTSSSTT CS
  Helicase_C 100 yiqriGRtgRag 111
                 y +r+GR+gR+g
  EEA22688.1 294 YLHRVGRAGRFG 305
                 **********86 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.3   0.0   9.8e-12   4.4e-08      28     170 ..       7     155 ..       3     156 .. 0.76

  Alignments for each domain:
  == domain 1  score: 33.3 bits;  conditional E-value: 9.8e-12
                 EEEESTTSTHHHHH.HHHHHHH-S.....-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--............-SEEEEEHHHHHHTH.. CS
      ResIII  28 likmaTGtGKTlva.aklierllkkgkeekflflvprkslleqtleefkkflseaykeigkkvsgdkkka.....kekdstnkkilvttiqsldadsee 120
                 l ++  G GKT v  + +   l   ++e ++l+++++++l  q ++e+++f++   + ++ ++ g + ++      ++++t  +i+v t  +l+a    
  EEA22688.1   7 LCQAKSGLGKTAVFvLTTLHGLDPVEGEVQVLVMCHTRELAYQIKNEYARFSKYLPQVKTAVFYGGTPMQkdielLSNKETRPNIVVGTPGRLNALV-- 103
                 667889********777777888888888****************9998887655444333333333333355677889999***************.. PP

                 ......HHHTTT-SEEEEETGGGTTS.....TTTHHHHHT---.SEEEEEESS-S CS
      ResIII 121 eeeeseellrdrfdviiiDEaHrlgak....kswreilekfke.avllglTATpe 170
                     +++l+  + + ++ DE+ ++ ++      ++ei ++ ++ + ++ ++AT+ 
  EEA22688.1 104 ---RDKKLSLRNVKAFVLDECDKMLDQidmrRDVQEIFRNTPAeKQVMMFSATLS 155
                 ...88889999999************943333555555444334888899**975 PP

>> CMS1  U3-containing 90S pre-ribosomal complex subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0     1e-06    0.0045     174     210 ..      85     121 ..      74     152 .. 0.80
   2 ?    0.3   0.0      0.08   3.6e+02     103     149 ..     185     233 ..     178     263 .. 0.77

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 1e-06
        CMS1 174 kksrigiavGtpgRildLleeeslsvdeLkrivlDas 210
                 k++r  i vGtpgR+  L++++ ls+ ++k  vlD  
  EEA22688.1  85 KETRPNIVVGTPGRLNALVRDKKLSLRNVKAFVLDEC 121
                 789999*****************************75 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.08
        CMS1 103 lpdyleelsef..akklvksaksngsPelLvltlaalRaaDlaralkkl 149
                 l +y  +lse   ++kl++        ++++   ++lRa +l + l++ 
  EEA22688.1 185 LQQYYIKLSEQekNRKLSELLDNLEFNQVIIFVKSTLRANELDKLLREC 233
                 5566445554411347777777777788899999999999999998875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (349 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       708  (0.0394891); expected 358.6 (0.02)
Passed bias filter:                      494  (0.0275531); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.30s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 2273.54
//
Query:       EEA22689.1  [L=270]
Description: cellulose-binding GDSL lipase/acylhydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.4e-10   40.7   0.1    3.1e-10   40.3   0.1    1.1  1  Lipase_GDSL  GDSL-like Lipase/Acylhydrolase


Domain annotation for each model (and alignments):
>> Lipase_GDSL  GDSL-like Lipase/Acylhydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.3   0.1   1.8e-14   3.1e-10       2     198 ..       4     259 ..       4     261 .. 0.82

  Alignments for each domain:
  == domain 1  score: 40.3 bits;  conditional E-value: 1.8e-14
                  EEEESHHHH.................................TTTHHHHHHHCCCCEECCCTTC.GCEEEEEEECTTHHHHHHHCCHECTTTECHHHH CS
                  xxxxxxxxx.................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Lipase_GDSL   2 vafGDSltd.................................Gdgaatlntiqlktpknlnefdlaldrianignkgasdnelqqllnkyplkseqlk 66 
                  +afGDS ++                                 G+ a+ +n++ +  ++   + ++  ++ a  g +++ ++  ++ l +y ++     
   EEA22689.1   4 FAFGDSWSAtgfnisstqpsatnpmgntaphpgtqsggnnwiGYLATRYNATLILAYSLAIAGATIDNSLATWGFGDMTSQIDAFQL-YYASRP---- 96 
                  79***********************99999999999999999999999999999999999888766666666666666655555555.333333.... PP

                  HCTTS.....EEEEE--CTCC-EECSSCTTTCEEHHHHHHHHHHHHHHHHHHHHTTEEEEEEE-SSTCH..CTCCCCHCCHHHHHHHHHHHHHHHHHH CS
                  xxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Lipase_GDSL  67 alhpd.....lviislGtNDsnlgkkstdaakkeaeeyiknlreaikelkeegapkaivvlvsppglgp..qeekdakklgekgnefvgeynqrlndl 157
                  a++p      +  + +G ND+ +g   +++  + ++ + +++r +i+++++ g++k++ ++++p   +p   ee+d  +  ++ +e+v+ yn+ ln++
   EEA22689.1  97 AYVPWttdntVTSFGIGINDVYYGFAHNEEPSAFVATLMNRYRPLIEQIYSDGIRKFLFLNCPPSTRSPqvHEENDLPEQFQRHAEMVTAYNEGLNSM 194
                  4555445589999********999999***********************************9888888999999*********************** PP

                  HH.......HCTEEEECHHHHHHHTHCCGCHCH...................TSSSB-HHHHHHHHH CS
                  xx.......xxxxxxxxxxxxxxxxxxxxxxxx...................xxxxxxxxxxxxxxx RF
  Lipase_GDSL 158 ae.......kdgfavvDlydelqglsgieqlka...................DglHpsekgyeklae 198
                  +        +++++v D ++ +++    +++++                    +lHp  k ++ +ae
   EEA22689.1 195 LFqfrddhkDATVVVYDSFQYMTRV--LDNPAEygyknatcmntdgsscvwwNNLHPGWKYHKYQAE 259
                  *99***9997777777777777777..4444445555667777755555555556**9999999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (270 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       389  (0.0216967); expected 358.6 (0.02)
Passed bias filter:                      329  (0.0183502); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.25s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 1933.46
//
Query:       EEA22690.1  [L=190]
Description: cellulose-binding GDSL lipase/acylhydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.2e-07   31.9   0.0    1.3e-07   31.8   0.0    1.0  1  Lipase_GDSL  GDSL-like Lipase/Acylhydrolase


Domain annotation for each model (and alignments):
>> Lipase_GDSL  GDSL-like Lipase/Acylhydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.8   0.0   7.5e-12   1.3e-07      73     198 ..      28     179 ..       6     181 .. 0.83

  Alignments for each domain:
  == domain 1  score: 31.8 bits;  conditional E-value: 7.5e-12
                  EEEE--CTCC-EECSSCTTTCEEHHHHHHHHHHHHHHHHHHHHTTEEEEEEE-SSTCH..CTCCCCHCCHHHHHHHHHHHHHHHHHHHH.......HC CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xx RF
  Lipase_GDSL  73 viislGtNDsnlgkkstdaakkeaeeyiknlreaikelkeegapkaivvlvsppglgp..qeekdakklgekgnefvgeynqrlndlae.......kd 161
                    + +G ND+ +g   +++  + ++ + +++r +i+++++ g++k++ ++++p   +p   ee+d  +  ++ +e+v+ yn+ ln+++        ++
   EEA22690.1  28 TSFGIGINDVYYGFAHNEEPSAFVATLMNRYRPLIEQIYSDGIRKFLFLNCPPSTRSPqvHEENDLPEQFQRHAEMVTAYNEGLNSMLFqfrddhkDA 125
                  5688******9999999**********************************9888888999999************************99***99977 PP

                  TEEEECHHHHHHHTHCCGCHCH...................TSSSB-HHHHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxx...................xxxxxxxxxxxxxxx RF
  Lipase_GDSL 162 gfavvDlydelqglsgieqlka...................DglHpsekgyeklae 198
                  +++v D ++ +++    +++++                    +lHp  k ++ +ae
   EEA22690.1 126 TVVVYDSFQYMTRV--LDNPAEygyknatcmntdgsscvwwNNLHPGWKYHKYQAE 179
                  77777777777777..4444445555677777755555555556*****9999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (190 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       514  (0.0286686); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.25s 00:00:00.72 Elapsed: 00:00:00.44
# Mc/sec: 1296.98
//
Query:       EEA22691.1  [L=181]
Description: hypothetical protein PMAA_093100 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.4e-05   24.0   0.0    0.00014   22.4   0.0    1.8  2  T5orf172     T5orf172 domain
  ------ inclusion threshold ------
      0.011   14.9   0.0      0.011   14.9   0.0    1.2  1  K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)


Domain annotation for each model (and alignments):
>> T5orf172  T5orf172 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0      0.33     3e+03      26      36 ..      48      66 ..      29     103 .. 0.65
   2 !   22.4   0.0   1.5e-08   0.00014       1      46 [.     125     178 ..     125     181 .] 0.82

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.33
    T5orf172 26 vqrRlkelsk........y 36
                +++Rlk l+         +
  EEA22691.1 48 LTERLKGLNAgdedemdlD 66
                6788888884333333331 PP

  == domain 2  score: 22.4 bits;  conditional E-value: 1.5e-08
    T5orf172   1 gyvYil...........tnessegetillKIGrtsnvqrRlkelskyptkppselev 46 
                 gyvYil           ++++++++ i+lK+G++ ++ +Rlk+ls   +++++e+e+
  EEA22691.1 125 GYVYILrvtpvtpdkdgAESTNNKK-IILKVGSCASIPKRLKTLS--EKCKHNEYEL 178
                 899**99999988777655555555.99*****************..6888888876 PP

>> K_oxygenase  L-lysine 6-monooxygenase (NADPH-requiring)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   0.0   1.2e-06     0.011      94     179 ..      89     175 ..      38     181 .] 0.81

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.2e-06
  K_oxygenase  94 sRkefedYlrWvasqleeqvrfgeeveevepdeeeee.....elltveskd.aegeeeelearnlvlgvGtepkiPevleklegkervvHss 179
                    +++++Y+    ++l++++ ++  +++v+ +  +++     ++l+v+  + +++ +e+++ ++++l vG+ ++iP+ l++l+  e++ H++
   EEA22691.1  89 QQRDYDKYM---PDRLHSSLYYDIVIKHVSTRLYKRDgpgyvYILRVTPVTpDKDGAESTNNKKIILKVGSCASIPKRLKTLS--EKCKHNE 175
                  555555555...68999999999999999876532222354566777766666666889999******************998..7888886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       340  (0.0189637); expected 358.6 (0.02)
Passed bias filter:                      268  (0.0149478); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.43
# Mc/sec: 1256.32
//
Query:       EEA22692.1  [L=68]
Description: hypothetical protein PMAA_093110 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (68 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       250  (0.0139439); expected 358.6 (0.02)
Passed bias filter:                      203  (0.0113224); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.46
# Mc/sec: 444.79
//
Query:       EEA22693.1  [L=764]
Description: 2-dehydropantoate 2-reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-23   83.2   0.0    2.1e-23   82.6   0.0    1.3  1  ApbA      Ketopantoate reductase PanE/ApbA
    5.4e-20   71.9   0.0      8e-20   71.3   0.0    1.3  1  ApbA_C    Ketopantoate reductase PanE/ApbA C terminal
  ------ inclusion threshold ------
       0.24   11.6   0.2        0.6   10.3   0.2    1.7  1  AGH       Androgenic gland hormone


Domain annotation for each model (and alignments):
>> ApbA  Ketopantoate reductase PanE/ApbA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.6   0.0   3.6e-27   2.1e-23       1     151 [.      10     166 ..      10     167 .. 0.93

  Alignments for each domain:
  == domain 1  score: 82.6 bits;  conditional E-value: 3.6e-27
                 EEEES-SHHHHHHHHHHHH.HTHCEEEE-SCHHHHHHHHHCEEEEETT.CEEEEEECEEECCH..SCCCCS-ESEEEE-SSGGGHHHHHHH.HGGGECT CS
        ApbA   1 iailGaGaiGsllaakLak.agadvtlilrsrrlealkknGlrltseg.geeilrppealsae..ekselepidlvivtvKayqteealee.ikplldp 94 
                 i+ +G++a++ +l ++L+  + +dvtl ++s  +e++ + G++++s++ g+e+++p+++++++  + s    +d+v+++vKa+++ + l + i+++++p
  EEA22693.1  10 ILSVGSNAVSAFLSWRLQTtNSCDVTLAWKSG-FESVAQYGVSFRSKTyGNERFKPRHVVRTPeeAASREVAYDYVVLCVKALPDIYDLGSiIESVVTP 107
                 7889***************9************.******************************987888889*******************99****** PP

                 CEEEEEESSS...SCHHHHHTTTSTTSEEEEEEEE-EEEEEETTEEEECS--EEEEEESS CS
        ApbA  95 ntvvlllqNG...lgheeelrealpkprvlggvtthgatregpgevhhagkgeikigela 151
                 + ++++l N+   lg+e +l++++p++ vl+ v+  +++++g   ++h g+ e+++g+++
  EEA22693.1 108 Q-HTCILVNTtntLGVESHLEQRFPTNVVLSLVSHMTINQTGLSDFEHEGSTEMWVGPAN 166
                 9.55555444444********************************************986 PP

>> ApbA_C  Ketopantoate reductase PanE/ApbA C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.3   0.0   1.3e-23     8e-20       1     124 [.     199     322 ..     199     323 .. 0.97

  Alignments for each domain:
  == domain 1  score: 71.3 bits;  conditional E-value: 1.3e-23
      ApbA_C   1 dirlarweKllinaainpltalldckn.gellespelralvrallkEalavaeaegvelseerleeaveavlektaanrsSMlqDveagrktEidyinG 98 
                 +ir+++  +++  +a+ p ++l++ +n  +lle+  +r+lv+ +++E+l++a  +g++++    +e+v a +++  + ++ M+qD +a+r++Ei++ + 
  EEA22693.1 199 NIRQEQFDRMIGPIAFHPASVLFNTPNhSQLLEKVGVRQLVNDVIDELLKLASTQGCSFDSG-YREKVIAKMTAPTEAQTTMYQDFLAHRPMEIETYLA 296
                 799************************999**************************999999.999999999999999********************* PP

      ApbA_C  99 avvklAeklgvetPvnellyellkal 124
                  +++lA + +v++P++e++y++l++l
  EEA22693.1 297 SPIRLAMESNVSLPRIETIYAMLHHL 322
                 ***********************976 PP

>> AGH  Androgenic gland hormone
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.2    0.0001       0.6      26      92 ..     460     523 ..     450     528 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.0001
         AGH  26 yfpterlskpcpwpnrekrsadedellfeededddffhpralsipsavesgdekeedelsllsrskr 92 
                 +   e  ++  p p  + r+ +    +f+e++++d+f p+ ++ p++++     + d++s+ sr  r
  EEA22693.1 460 LREREMNLRRGPGPRGGPRAPPPPRSVFDEEDEEDYFDPQDFRPPPGIDID---NIDMMSVTSRRTR 523
                 555566678889999999999999*******************99998754...4588888888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (764 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      249  (0.0138881); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.49
# Mc/sec: 4705.69
//
Query:       EEA22694.1  [L=83]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    6.2e-22   77.7   0.7    7.8e-22   77.4   0.7    1.1  1  DASH_Hsk3  DASH complex subunit Hsk3 like
  ------ inclusion threshold ------
      0.025   13.3   0.0       0.03   13.1   0.0    1.0  1  BBS2_C     Ciliary BBSome complex subunit 2, C-terminal


Domain annotation for each model (and alignments):
>> DASH_Hsk3  DASH complex subunit Hsk3 like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.4   0.7   8.7e-26   7.8e-22       1      45 []       6      50 ..       6      50 .. 0.97

  Alignments for each domain:
  == domain 1  score: 77.4 bits;  conditional E-value: 8.7e-26
   DASH_Hsk3  1 qRqyshLasqLaqLqaNLadteellevtseQaesirkLGklhasl 45
                +Rqy+hL+sqLaqL+a+Ladte+l+++t++Qa ++r+LG+++++l
  EEA22694.1  6 ARQYAHLHSQLAQLNAHLADTENLVRMTAVQAGDMRFLGGYVGGL 50
                6*****************************************985 PP

>> BBS2_C  Ciliary BBSome complex subunit 2, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   3.3e-06      0.03     318     353 ..      10      45 ..       4      48 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 3.3e-06
      BBS2_C 318 delnevrqkltaemadssnlvkslivraEDarlled 353
                 + l++  ++l+a +ad+ nlv+ + v+a D+r l+ 
  EEA22694.1  10 AHLHSQLAQLNAHLADTENLVRMTAVQAGDMRFLGG 45 
                 6789999*************************9975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (83 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       475  (0.0264934); expected 358.6 (0.02)
Passed bias filter:                      343  (0.019131); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.37u 0.26s 00:00:00.63 Elapsed: 00:00:00.42
# Mc/sec: 589.93
//
Query:       EEA22695.1  [L=269]
Description: phosphoglycerate mutase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.8e-31  108.7   1.2    2.9e-15   56.5   0.0    3.3  3  His_Phos_1  Histidine phosphatase superfamily (branch 1)


Domain annotation for each model (and alignments):
>> His_Phos_1  Histidine phosphatase superfamily (branch 1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.5   0.0   1.6e-19   2.9e-15       2      68 ..       7      80 ..       6      90 .. 0.84
   2 !   18.8   0.0   5.9e-08    0.0011      68     117 ..     104     152 ..      96     156 .. 0.72
   3 !   30.7   0.0   1.3e-11   2.3e-07     107     185 ..     165     253 ..     155     258 .. 0.78

  Alignments for each domain:
  == domain 1  score: 56.5 bits;  conditional E-value: 1.6e-19
                EEEE---BTTB--....TT----B-HHHHHHHHHHHHHHTT.......S---EEEE-SSHHHHHHHHHHHHCTT CS
  His_Phos_1  2 yLvRHGetewnaegrlqgrtdvpLteeGreqAealaerlag.......epidaiysSplkRarqTaeliaealg 68
                ++vRHGetew+ +gr  g td+pLt +G++ ++a++++l g        +++++y+Sp kRa++T el+  +++
  EEA22695.1  7 FIVRHGETEWSLNGRHTGTTDIPLTVNGEKRMRATGKALVGndrliapKRLNHVYVSPRKRAQRTFELLHIECK 80
                69************************************7664444333777777*************9987766 PP

  == domain 2  score: 18.8 bits;  conditional E-value: 5.9e-08
                 T--EEE-GGGS----GGGTT-B.HHHHHH..HS.HHHHHHHHH-GGG-BS- CS
  His_Phos_1  68 glpveldegLrEidfGdweglttaeiaeeypee.leawlrdpadvrppggE 117
                 + ++e+++++rE+d+Gd+eglt+a+i+  + ++ l +w+ +++    pggE
  EEA22695.1 104 EADIEVTDAIREWDYGDYEGLTSAQIRVLRVQQgLPKWDIWKD--GCPGGE 152
                 47899********************997554440344444433..355555 PP

  == domain 3  score: 30.7 bits;  conditional E-value: 1.3e-11
                 HHH-GGG-B..S-BHHHHHHHHHHHHHHHHHHTTTSE..........EEEEE-HHHHHHHHHHHHT--GGGGGGB---TT-EEEEEE-SS- CS
  His_Phos_1 107 dpadvrppg..gEsledvaaRvaaaleelaarheget..........vlvVsHggvirallarllglpleelrrleldnaslsvlefdegg 185
                 ++   + p+  g s++dv +R++ ++ +l+a++++            vlvV+Hg+++ra+++r++g pl++   l l+  ++  l++++++
  EEA22695.1 165 EER-KKEPDcyGRSPADVCRRLDTFIADLRAKNHKPCfsdpenekgdVLVVAHGHILRAFAMRWVGQPLTDT-ALILEAGGVGTLSYEHHN 253
                 222.2333346****************99999876555555666788**********************995.666888888888888775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (269 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       251  (0.0139997); expected 358.6 (0.02)
Passed bias filter:                      238  (0.0132746); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.25s 00:00:00.67 Elapsed: 00:00:00.40
# Mc/sec: 2010.21
//
Query:       EEA22696.1  [L=504]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.5e-76  253.0   5.7    2.6e-19   69.6   0.2    6.4  5  Ank_2       Ankyrin repeats (3 copies)
    8.1e-66  217.6  13.2    2.6e-11   43.8   0.0    9.4 10  Ank_4       Ankyrin repeats (many copies)
    4.9e-62  198.5   0.2    1.9e-05   24.7   0.0   13.1 13  Ank_3       Ankyrin repeat
    2.7e-61  201.5   9.5    1.1e-05   25.6   0.0   12.5 13  Ank         Ankyrin repeat
    4.2e-55  183.1   5.5    3.4e-10   40.0   0.1    8.6  9  Ank_5       Ankyrin repeats (many copies)
    0.00018   21.4   2.2    0.00019   21.3   0.6    1.9  2  F-box-like  F-box-like
  ------ inclusion threshold ------
      0.012   15.5   0.1         28    4.7   0.0    5.5  7  PEGA        PEGA domain


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.2   0.1   2.3e-16   5.8e-13       1      83 []      55     148 ..      55     148 .. 0.84
   2 !   61.9   0.1   2.5e-20   6.5e-17       1      83 []     155     251 ..     155     251 .. 0.85
   3 !   69.6   0.2     1e-22   2.6e-19       2      83 .]     225     319 ..     224     319 .. 0.85
   4 !   35.6   0.0   4.2e-12   1.1e-08      27      83 .]     323     387 ..     319     387 .. 0.86
   5 !   46.9   0.0   1.2e-15   3.1e-12       9      74 ..     407     484 ..     396     491 .. 0.82

  Alignments for each domain:
  == domain 1  score: 49.2 bits;  conditional E-value: 2.3e-16
       Ank_2   1 LhlAakngnlelvklLl.egadpn.k.ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlek.gadinlkd 83 
                 L +Aak g+  + +l + ega+++ + +g+t L +Aa++g++ +v lLle         d +grt+L  Aa +gh+++vk+Ll   ++++n kd
  EEA22696.1  55 LLWAAKVGSEATARLSIrEGANLDlSeDGRTLLLLAAQGGHTAVVVLLLETenffidsKDTYGRTALSQAALYGHERLVKWLLHTgKVNVNSKD 148
                 678999996667777789999999856**********************9445786655599*********************55456777765 PP

  == domain 2  score: 61.9 bits;  conditional E-value: 2.5e-20
       Ank_2   1 LhlAakngnlelvklLl....egadpnk..ngktaLhyAakngnleivklLleh....ad...ndgrtpLhyAarsghleivklLlek.gadinlkd 83 
                 L++Aa+ g+  +vklL+    +++d+++   g+t+L +A+ ng++ +vklLle     ++   n+g tp+ +Aa +gh+ +vklLl+  ++d+++kd
  EEA22696.1 155 LFYAAEGGHEAIVKLLImdgsSNFDIKDrfYGQTPLSIATANGHKSTVKLLLETgkvdVNskcNNGSTPISIAATKGHEALVKLLLQTeKVDVDIKD 251
                 789*****999*****99743335554479**********************9667664477899*********************55578999887 PP

  == domain 3  score: 69.6 bits;  conditional E-value: 1e-22
       Ank_2   2 hlAakngnlelvklLl..egadpn..k.ngktaLhyAakngnleivklLle..h.....adndgrtpLhyAarsghleivklLlek.gadinlkd 83 
                  +Aa +g+  lvklLl  e++d++  + +g+t+L +Aa ng++ +v+lLle  +      dndgrtpL +Aa +gh  +vklLle  ++din++d
  EEA22696.1 225 SIAATKGHEALVKLLLqtEKVDVDikDhDGRTPLSHAANNGHEIVVRLLLEigKvdansKDNDGRTPLCVAAIEGHKAVVKLLLETgKVDINARD 319
                 5899999999******999999998537*************95558****96525644555***********************88568999987 PP

  == domain 4  score: 35.6 bits;  conditional E-value: 4.2e-12
       Ank_2  27 ktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlek.gadinlkd 83 
                 +t+L++A+ + ++ ivklLl         +dn+g +pL  A+ + +  +vklLl   ++d+n +d
  EEA22696.1 323 RTPLFWAICRKHEAIVKLLLGTkdvdvnlTDNEGVSPLSQAINNRQKTLVKLLLATeNVDVNSRD 387
                 8***********9*******74466656666***********99999*******54589999987 PP

  == domain 5  score: 46.9 bits;  conditional E-value: 1.2e-15
       Ank_2   9 nlelvklLl..egadpn..k.ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLle 74 
                 + e ++lLl   ++d+n  + +g t+L +Aa+ gn+e+v++Lle        +dn g tp+ +Aa +gh e+ klL +
  EEA22696.1 407 DEEYMELLLetGNVDLNckDnDGYTPLSHAAILGNVEMVQFLLETgqvdvnsVDNLGFTPMRWAAYQGHKEVKKLLAD 484
                 4578999**866688888537**********************9666675566699*************999999975 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   0.1   5.3e-07    0.0014       2      55 .]      52     103 ..      51     103 .. 0.93
   2 !   43.8   0.0     1e-14   2.6e-11       1      55 []     117     171 ..     117     171 .. 0.95
   3 !   28.8   0.0   5.3e-10   1.4e-06       3      55 .]     188     240 ..     186     240 .. 0.91
   4 !   32.1   0.0   4.6e-11   1.2e-07       2      55 .]     221     274 ..     220     274 .. 0.96
   5 !   32.3   0.1   4.1e-11     1e-07       1      55 []     254     308 ..     254     308 .. 0.95
   6 !   35.3   0.0   4.8e-12   1.2e-08       1      55 []     288     342 ..     288     342 .. 0.96
   7 !   23.0   0.0   3.5e-08   8.9e-05       2      55 .]     323     376 ..     322     376 .. 0.96
   8 !   17.2   0.0   2.2e-06    0.0056       3      43 ..     358     399 ..     356     400 .. 0.90
   9 !   14.1   0.1   2.1e-05     0.055      10      42 ..     404     436 ..     402     437 .. 0.85
  10 !   39.7   0.0     2e-13   5.1e-10       2      54 ..     430     482 ..     429     483 .. 0.92

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 5.3e-07
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++aL +aa+ g + ++rl +  ga+++ +  ++G+t+l  Aa++g+  ++ lLl
  EEA22696.1  52 SSALLWAAKVGSEATARLSIREGANLDLS--EDGRTLLLLAAQGGHTAVVVLLL 103
                 689*****************77***9996..99*****************9997 PP

  == domain 2  score: 43.8 bits;  conditional E-value: 1e-14
       Ank_4   1 eltaLhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++taL +aa +g+++lv++Ll + ++++n   ++ G+t+l +Aa +g+  i+klL+
  EEA22696.1 117 GRTALSQAALYGHERLVKWLLHTgKVNVNSK-DDHGQTPLFYAAEGGHEAIVKLLI 171
                 589******************9967*****9.888********************8 PP

  == domain 3  score: 28.8 bits;  conditional E-value: 5.3e-10
       Ank_4   3 taLhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAakrgnveilklLl 55 
                 t+L  a + g+  +v+lLle+ ++d+n    ++G t++ iAa +g+   +klLl
  EEA22696.1 188 TPLSIATANGHKSTVKLLLETgKVDVNSK-CNNGSTPISIAATKGHEALVKLLL 240
                 677778889************77*****9.777********************8 PP

  == domain 4  score: 32.1 bits;  conditional E-value: 4.6e-11
       Ank_4   2 ltaLhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +t++  aa +g++ lv+lLl++ ++d++   + +G+t+l +Aa +g+  +++lLl
  EEA22696.1 221 STPISIAATKGHEALVKLLLQTeKVDVDIK-DHDGRTPLSHAANNGHEIVVRLLL 274
                 68999*****************9******9.**********************98 PP

  == domain 5  score: 32.3 bits;  conditional E-value: 4.1e-11
       Ank_4   1 eltaLhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++t+L +aa+ g++ +vrlLle  ++d n   +++G+t+l  Aa  g++ ++klLl
  EEA22696.1 254 GRTPLSHAANNGHEIVVRLLLEIgKVDANSK-DNDGRTPLCVAAIEGHKAVVKLLL 308
                 589*******************967*****9.999********************8 PP

  == domain 6  score: 35.3 bits;  conditional E-value: 4.8e-12
       Ank_4   1 eltaLhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++t+L  aai+g+  +v+lLle+ ++dina+ +  ++t+l  A+ r +  i+klLl
  EEA22696.1 288 GRTPLCVAAIEGHKAVVKLLLETgKVDINAR-DVIDRTPLFWAICRKHEAIVKLLL 342
                 589********************77******.988********************8 PP

  == domain 7  score: 23.0 bits;  conditional E-value: 3.5e-08
       Ank_4   2 ltaLhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +t+L++a+   ++ +v+lLl + ++d+n + +++G ++l  A+ + ++  +klLl
  EEA22696.1 323 RTPLFWAICRKHEAIVKLLLGTkDVDVNLT-DNEGVSPLSQAINNRQKTLVKLLL 376
                 69******************9968******.999*******************98 PP

  == domain 8  score: 17.2 bits;  conditional E-value: 2.2e-06
       Ank_4   3 taLhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAa 43 
                 ++L +a++  +  lv+lLl++ ++d+n +d ++G+t++ +A+
  EEA22696.1 358 SPLSQAINNRQKTLVKLLLATeNVDVNSRDCIYGNTPFSYAL 399
                 67888888899999*******99******99*******9997 PP

  == domain 9  score: 14.1 bits;  conditional E-value: 2.1e-05
       Ank_4  10 isgrlelvrlLlek.gadinaqdnrsGetalhiA 42 
                 ++ ++e+ +lLle+ ++d+n+  +++G t+l +A
  EEA22696.1 404 SQRDEEYMELLLETgNVDLNCK-DNDGYTPLSHA 436
                 567899********55*****9.999****9776 PP

  == domain 10  score: 39.7 bits;  conditional E-value: 2e-13
       Ank_4   2 ltaLhyaaisgrlelvrlLlekg.adinaqdnrsGetalhiAakrgnveilklL 54 
                 +t+L +aai g++e+v++Lle+g +d+n + ++ G+t++  Aa+ g++e+ klL
  EEA22696.1 430 YTPLSHAAILGNVEMVQFLLETGqVDVNSV-DNLGFTPMRWAAYQGHKEVKKLL 482
                 79********************66******.888*************9986666 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   0.0       0.6   1.5e+03       3      29 ..      52      77 ..      50      79 .. 0.75
   2 !   11.9   0.0   0.00011      0.27       1      25 [.      82     108 ..      82     112 .. 0.86
   3 !   17.4   0.0   1.7e-06    0.0043       1      30 [.     116     145 ..     116     146 .. 0.94
   4 !   16.3   0.0   3.8e-06    0.0097       1      25 [.     150     173 ..     150     180 .. 0.88
   5 !   17.9   0.0   1.2e-06     0.003       1      30 [.     185     214 ..     185     215 .. 0.96
   6 !   13.6   0.0     3e-05     0.076       1      31 []     219     249 ..     219     249 .. 0.94
   7 !   21.7   0.0   6.7e-08   0.00017       1      30 [.     253     282 ..     253     283 .. 0.95
   8 !   16.6   0.0   3.2e-06    0.0081       1      31 []     287     317 ..     287     317 .. 0.96
   9 !   13.1   0.0   4.5e-05      0.11       3      30 ..     323     350 ..     322     351 .. 0.96
  10 !   10.6   0.0   0.00028      0.71       2      30 ..     356     384 ..     355     385 .. 0.94
  11 !    9.9   0.0   0.00047       1.2       1      31 []     390     424 ..     390     424 .. 0.89
  12 !   24.7   0.0   7.4e-09   1.9e-05       1      30 [.     428     457 ..     428     458 .. 0.96
  13 ?    5.7   0.0     0.011        29       2      23 ..     463     483 ..     462     487 .. 0.87

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.6
       Ank_3  3 etpLhlAarsgnleivkfLlenkgadv 29
                 ++L +Aa+ g+ + +++ ++  ga++
  EEA22696.1 52 SSALLWAAKVGSEATARLSIR-EGANL 77
                589******999876776666.56665 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 0.00011
       Ank_3   1 nGetpLhlAarsgnleivkfLle..nk 25 
                 +G+t+L lAa  g++++v +Lle  n+
  EEA22696.1  82 DGRTLLLLAAQGGHTAVVVLLLEteNF 108
                 69********************96555 PP

  == domain 3  score: 17.4 bits;  conditional E-value: 1.7e-06
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvn 30 
                 +G+t+L +Aa++g+  +vk+Ll    ++vn
  EEA22696.1 116 YGRTALSQAALYGHERLVKWLLHTGKVNVN 145
                 79*********************9999988 PP

  == domain 4  score: 16.3 bits;  conditional E-value: 3.8e-06
       Ank_3   1 nGetpLhlAarsgnleivkfLlenk 25 
                 +G+tpL++Aa+ g+ +ivk+L+   
  EEA22696.1 150 HGQTPLFYAAEGGHEAIVKLLIM-D 173
                 79********************8.3 PP

  == domain 5  score: 17.9 bits;  conditional E-value: 1.2e-06
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvn 30 
                 +G+tpL +A  +g+ + vk+Lle   +dvn
  EEA22696.1 185 YGQTPLSIATANGHKSTVKLLLETGKVDVN 214
                 79*************99***********99 PP

  == domain 6  score: 13.6 bits;  conditional E-value: 3e-05
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvna 31 
                 nG tp+ +Aa  g+ ++vk+Ll+   +dv++
  EEA22696.1 219 NGSTPISIAATKGHEALVKLLLQTEKVDVDI 249
                 799********************99999985 PP

  == domain 7  score: 21.7 bits;  conditional E-value: 6.7e-08
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvn 30 
                 +G+tpL +Aa +g+  +v++Lle+  +d n
  EEA22696.1 253 DGRTPLSHAANNGHEIVVRLLLEIGKVDAN 282
                 69*********************9999988 PP

  == domain 8  score: 16.6 bits;  conditional E-value: 3.2e-06
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvna 31 
                 +G+tpL +Aa  g+ ++vk+Lle   +d+na
  EEA22696.1 287 DGRTPLCVAAIEGHKAVVKLLLETGKVDINA 317
                 69***************************96 PP

  == domain 9  score: 13.1 bits;  conditional E-value: 4.5e-05
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvn 30 
                 +tpL++A+   + +ivk+Ll  k +dvn
  EEA22696.1 323 RTPLFWAICRKHEAIVKLLLGTKDVDVN 350
                 8*************************99 PP

  == domain 10  score: 10.6 bits;  conditional E-value: 0.00028
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                 G +pL +A+ +   ++vk+Ll   ++dvn
  EEA22696.1 356 GVSPLSQAINNRQKTLVKLLLATENVDVN 384
                 889*******************999*999 PP

  == domain 11  score: 9.9 bits;  conditional E-value: 0.00047
       Ank_3   1 nGetpLhlAarsgnl....eivkfLlenkgadvna 31 
                 +G+tp+ +A++ +      e++++Lle  ++d+n+
  EEA22696.1 390 YGNTPFSYALSPALSqrdeEYMELLLETGNVDLNC 424
                 79*************776458***********996 PP

  == domain 12  score: 24.7 bits;  conditional E-value: 7.4e-09
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvn 30 
                 +G+tpL +Aa  gn+e+v+fLle   +dvn
  EEA22696.1 428 DGYTPLSHAAILGNVEMVQFLLETGQVDVN 457
                 69**************************99 PP

  == domain 13  score: 5.7 bits;  conditional E-value: 0.011
       Ank_3   2 GetpLhlAarsgnleivkfLle 23 
                 G tp+ +Aa +g+ e vk Ll 
  EEA22696.1 463 GFTPMRWAAYQGHKE-VKKLLA 483
                 88*************.888775 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       4.7   1.2e+04       6      28 ..      55      78 ..      53      79 .. 0.53
   2 !   10.0   0.0   0.00039      0.99       1      22 [.      82     103 ..      82     114 .. 0.89
   3 !   20.7   0.0   1.6e-07   0.00041       1      32 []     116     149 ..     116     149 .. 0.93
   4 !   21.8   0.0     7e-08   0.00018       1      31 [.     150     182 ..     150     183 .. 0.89
   5 !   18.7   0.0   6.8e-07    0.0017       1      30 [.     185     216 ..     185     218 .. 0.91
   6 !   15.0   0.0     1e-05     0.026       1      31 [.     219     251 ..     219     252 .. 0.88
   7 !   19.6   0.1   3.6e-07   0.00092       1      32 []     253     286 ..     253     286 .. 0.90
   8 !   25.6   0.0   4.5e-09   1.1e-05       1      31 [.     287     319 ..     287     320 .. 0.95
   9 !   19.3   0.0   4.3e-07    0.0011       3      32 .]     323     354 ..     322     354 .. 0.89
  10 !    8.4   0.0    0.0012         3       2      32 .]     356     388 ..     355     388 .. 0.86
  11 !    8.1   0.0    0.0015         4       1      32 []     390     427 ..     390     427 .. 0.82
  12 !   22.9   0.0   3.1e-08   8.1e-05       1      32 []     428     461 ..     428     461 .. 0.95
  13 ?    3.5   0.0     0.042   1.1e+02       2      21 ..     463     482 ..     462     502 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 4.7
                HHHHHHHTTHHHHHHH.H.TTTSTT CS
         Ank  6 LHlAatngkkriiklL.L.hGAnln 28
                L +Aa  g++  ++ L +  GAnl+
  EEA22696.1 55 LLWAAKVGSEATAR-LsIrEGANLD 78
                55666555544555.3254578876 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00039
                 TSBBHHHHHHHHTTHHHHHHHH CS
         Ank   1 dGnTPLHlAatngkkriiklLL 22 
                 dG+T L lAa++g++ ++ lLL
  EEA22696.1  82 DGRTLLLLAAQGGHTAVVVLLL 103
                 8******************999 PP

  == domain 3  score: 20.7 bits;  conditional E-value: 1.6e-07
                 TSBBHHHHHHHHTTHHHHHHHHT.T.TSTTCBTT CS
         Ank   1 dGnTPLHlAatngkkriiklLLh.G.Anlnaldn 32 
                 +G+T+L  Aa +g++r +k+LLh G  n+n++d+
  EEA22696.1 116 YGRTALSQAALYGHERLVKWLLHtGkVNVNSKDD 149
                 69********************66999****996 PP

  == domain 4  score: 21.8 bits;  conditional E-value: 7e-08
                 TSBBHHHHHHHHTTHHHHHHHH.TT.TSTTCBT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hG.Anlnald 31 
                 +G TPL +Aa +g++ i+klL+ +G +n +++d
  EEA22696.1 150 HGQTPLFYAAEGGHEAIVKLLImDGsSNFDIKD 182
                 69********************99967777777 PP

  == domain 5  score: 18.7 bits;  conditional E-value: 6.8e-07
                 TSBBHHHHHHHHTTHHHHHHHH.TT.TSTTCB CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hG.Anlnal 30 
                 +G TPL +A  ng+k+ +klLL  G  ++n++
  EEA22696.1 185 YGQTPLSIATANGHKSTVKLLLeTGkVDVNSK 216
                 69******999***********8898999986 PP

  == domain 6  score: 15.0 bits;  conditional E-value: 1e-05
                 TSBBHHHHHHHHTTHHHHHHHH.TT.TSTTCBT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hG.Anlnald 31 
                 +G TP  +Aat g++  +klLL     +++++d
  EEA22696.1 219 NGSTPISIAATKGHEALVKLLLqTEkVDVDIKD 251
                 799*******************64349999988 PP

  == domain 7  score: 19.6 bits;  conditional E-value: 3.6e-07
                 TSBBHHHHHHHHTTHHHHHHHH.TT.TSTTCBTT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hG.Anlnaldn 32 
                 dG+TPL  Aa+ng++ +++lLL  G  + n++dn
  EEA22696.1 253 DGRTPLSHAANNGHEIVVRLLLeIGkVDANSKDN 286
                 8*********************669888888886 PP

  == domain 8  score: 25.6 bits;  conditional E-value: 4.5e-09
                 TSBBHHHHHHHHTTHHHHHHHH.TT.TSTTCBT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hG.Anlnald 31 
                 dG+TPL +Aa +g+k ++klLL  G  ++na+d
  EEA22696.1 287 DGRTPLCVAAIEGHKAVVKLLLeTGkVDINARD 319
                 8*********99**********98999*****9 PP

  == domain 9  score: 19.3 bits;  conditional E-value: 4.3e-07
                 BBHHHHHHHHTTHHHHHHHHTT...TSTTCBTT CS
         Ank   3 nTPLHlAatngkkriiklLLhG...Anlnaldn 32 
                 +TPL +A++++++ i+klLL G    ++n++dn
  EEA22696.1 323 RTPLFWAICRKHEAIVKLLL-GtkdVDVNLTDN 354
                 6*******************.554599***997 PP

  == domain 10  score: 8.4 bits;  conditional E-value: 0.0012
                 SBBHHHHHHHHTTHHHHHHHH.T.TTSTTCBTT CS
         Ank   2 GnTPLHlAatngkkriiklLL.h.GAnlnaldn 32 
                 G +PL  A++n +k  +klLL     ++n++d+
  EEA22696.1 356 GVSPLSQAINNRQKTLVKLLLaTeNVDVNSRDC 388
                 999******877799******85379****996 PP

  == domain 11  score: 8.1 bits;  conditional E-value: 0.0015
                 TSBBHHHHHHHHTT....HHHHHHHH.TT.TSTTCBTT CS
         Ank   1 dGnTPLHlAatngk....kriiklLL.hG.Anlnaldn 32 
                 +GnTP  +A +++     ++  +lLL  G  +ln +dn
  EEA22696.1 390 YGNTPFSYALSPALsqrdEEYMELLLeTGnVDLNCKDN 427
                 6*******985555555599******989899**9997 PP

  == domain 12  score: 22.9 bits;  conditional E-value: 3.1e-08
                 TSBBHHHHHHHHTTHHHHHHHH.TT.TSTTCBTT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hG.Anlnaldn 32 
                 dG+TPL  Aa  g+++++++LL  G  ++n++dn
  EEA22696.1 428 DGYTPLSHAAILGNVEMVQFLLeTGqVDVNSVDN 461
                 9******99999**********98999*****98 PP

  == domain 13  score: 3.5 bits;  conditional E-value: 0.042
                 SBBHHHHHHHHTTHHHHHHH CS
         Ank   2 GnTPLHlAatngkkriiklL 21 
                 G+TP  +Aa+ g+k++ klL
  EEA22696.1 463 GFTPMRWAAYQGHKEVKKLL 482
                 9********99***999966 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.4   0.0   1.6e-06     0.004       5      53 ..      74     121 ..      71     122 .. 0.86
   2 !   12.4   0.0   5.8e-05      0.15      11      36 ..     112     137 ..     110     140 .. 0.91
   3 !   27.5   0.0   1.1e-09   2.8e-06       1      56 []     136     193 ..     136     193 .. 0.96
   4 !   34.3   0.0   8.2e-12   2.1e-08       1      56 []     205     261 ..     205     261 .. 0.98
   5 !   31.1   0.0   7.8e-11     2e-07       1      53 [.     239     292 ..     239     292 .. 0.95
   6 !   27.8   0.0   8.8e-10   2.2e-06       1      53 [.     273     326 ..     273     326 .. 0.97
   7 !   26.2   0.1   2.8e-09   7.2e-06       6      56 .]     346     398 ..     340     398 .. 0.92
   8 !   40.0   0.1   1.3e-13   3.4e-10       1      53 [.     414     467 ..     414     470 .. 0.97
   9 !   14.3   0.0   1.5e-05     0.039       1      35 [.     448     482 ..     448     486 .. 0.91

  Alignments for each domain:
  == domain 1  score: 17.4 bits;  conditional E-value: 1.6e-06
       Ank_5   5 gpadvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltal 53 
                 g a+++ ++ +g t L +Aa +g+  vv lLl  ++  ++ +d +G+tal
  EEA22696.1  74 G-ANLDLSE-DGRTLLLLAAQGGHTAVVVLLLeTENFFIDSKDTYGRTAL 121
                 4.6665554.555************************************8 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 5.8e-05
       Ank_5  11 rldgggntpLhvAakygaadvvrlLl 36 
                  +d +g t+L +Aa yg+ ++v++Ll
  EEA22696.1 112 SKDTYGRTALSQAALYGHERLVKWLL 137
                 67999********************9 PP

  == domain 3  score: 27.5 bits;  conditional E-value: 1.1e-09
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrG.ltaldlA 56 
                 Ll+ g ++vn +d +g+tpL +Aa++g+  +v+lL+ +  ++ +++d  + +t+l +A
  EEA22696.1 136 LLHTGKVNVNSKDDHGQTPLFYAAEGGHEAIVKLLImDGSSNFDIKDRFYgQTPLSIA 193
                 678889********************************************9****998 PP

  == domain 4  score: 34.3 bits;  conditional E-value: 8.2e-12
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltaldlA 56 
                 Lle g +dvn ++++g tp+ +Aa +g+  +v+lLl  + +d +++d +G+t+l +A
  EEA22696.1 205 LLETGKVDVNSKCNNGSTPISIAATKGHEALVKLLLqTEKVDVDIKDHDGRTPLSHA 261
                 8999**************************************************877 PP

  == domain 5  score: 31.1 bits;  conditional E-value: 7.8e-11
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltal 53 
                 Ll+   +dv+ +d +g tpL +Aa++g+  vvrlLl    +d+n +d++G+t+l
  EEA22696.1 239 LLQTEKVDVDIKDHDGRTPLSHAANNGHEIVVRLLLeIGKVDANSKDNDGRTPL 292
                 5666679**********************************************8 PP

  == domain 6  score: 27.8 bits;  conditional E-value: 8.8e-10
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltal 53 
                 Lle g +d n +d++g tpL+vAa  g+  vv+lLl    +d+n++d   +t+l
  EEA22696.1 273 LLEIGKVDANSKDNDGRTPLCVAAIEGHKAVVKLLLeTGKVDINARDVIDRTPL 326
                 899999*****************************************9999997 PP

  == domain 7  score: 26.2 bits;  conditional E-value: 2.8e-09
       Ank_5   6 padvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrG.ltaldlA 56 
                 ++dvn +d++g++pL +A++++  ++v+lLl  +++d n +d  + +t++ +A
  EEA22696.1 346 DVDVNLTDNEGVSPLSQAINNRQKTLVKLLLaTENVDVNSRDCIYgNTPFSYA 398
                 69***************************************977779999988 PP

  == domain 8  score: 40.0 bits;  conditional E-value: 1.3e-13
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl.argadlnltdsrGltal 53 
                 Lle g++d+n++d++g+tpL +Aa  g+ ++v++Ll   ++d n  d+ G t++
  EEA22696.1 414 LLETGNVDLNCKDNDGYTPLSHAAILGNVEMVQFLLeTGQVDVNSVDNLGFTPM 467
                 899*************************************************98 PP

  == domain 9  score: 14.3 bits;  conditional E-value: 1.5e-05
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlL 35 
                 Lle g++dvn  d+ g+tp+ +Aa++g+ +v +lL
  EEA22696.1 448 LLETGQVDVNSVDNLGFTPMRWAAYQGHKEVKKLL 482
                 89*************************98887776 PP

>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.6   7.2e-08   0.00019       2      46 ..       4      47 ..       3      49 .. 0.92
   2 ?   -2.0   0.0       1.3   3.4e+03      32      42 ..     318     328 ..     318     329 .. 0.91

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 7.2e-08
  F-box-like  2 srLPdEiLlqIFsyLppsdLlr.lalVCrrWrrvaldtplLWrrlv 46
                ++LP+E+L  I ++L+ +++++ l++V +r + +   +p+L+r  +
  EEA22696.1  4 DHLPTELLRLIAHFLDKESYINtLCRVNSRLYHAL--NPFLYRYNC 47
                7*********************99**********9..78***9766 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 1.3
  F-box-like  32 rrvaldtplLW 42 
                 r+v+ +tpl+W
  EEA22696.1 318 RDVIDRTPLFW 328
                 799******** PP

>> PEGA  PEGA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0      0.27   6.9e+02      17      35 ..     144     163 ..     140     169 .. 0.68
   2 ?    4.7   0.0     0.011        28      18      36 ..     181     199 ..     176     208 .. 0.77
   3 ?    0.6   0.0      0.21   5.4e+02      21      35 ..     218     232 ..     209     237 .. 0.77
   4 ?   -1.9   0.0       1.2   3.1e+03      23      36 ..     254     266 ..     244     272 .. 0.71
   5 ?   -1.1   0.0      0.72   1.8e+03      22      41 ..     287     307 ..     284     310 .. 0.74
   6 ?   -1.6   0.0         1   2.6e+03      22      31 ..     390     399 ..     379     402 .. 0.73
   7 ?   -1.1   0.0      0.69   1.8e+03      21      38 ..     461     478 ..     453     479 .. 0.75

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.27
        PEGA  17 idGk.ylGkTPvtlsleaGn 35 
                 ++ k ++G+TP+ ++ e G 
  EEA22696.1 144 VNSKdDHGQTPLFYAAEGGH 163
                 5544269****998876654 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.011
        PEGA  18 dGkylGkTPvtlsleaGny 36 
                   + +G+TP++++ ++G  
  EEA22696.1 181 KDRFYGQTPLSIATANGHK 199
                 5689*********888754 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.21
        PEGA  21 ylGkTPvtlsleaGn 35 
                 + G+TP++++  +G 
  EEA22696.1 218 NNGSTPISIAATKGH 232
                 679*****9977775 PP

  == domain 4  score: -1.9 bits;  conditional E-value: 1.2
        PEGA  23 GkTPvtlsleaGny 36 
                 G+TP++ +  +G +
  EEA22696.1 254 GRTPLSHAANNG-H 266
                 99**99887776.4 PP

  == domain 5  score: -1.1 bits;  conditional E-value: 0.72
        PEGA  22 lGkTPvtls.leaGnyslrve 41 
                  G+TP+ ++ +e  +  +++ 
  EEA22696.1 287 DGRTPLCVAaIEGHKAVVKLL 307
                 59****999887766666665 PP

  == domain 6  score: -1.6 bits;  conditional E-value: 1
        PEGA  22 lGkTPvtlsl 31 
                 +G+TP +++l
  EEA22696.1 390 YGNTPFSYAL 399
                 8****99886 PP

  == domain 7  score: -1.1 bits;  conditional E-value: 0.69
        PEGA  21 ylGkTPvtlsleaGnysl 38 
                 +lG TP++ +  +G  ++
  EEA22696.1 461 NLGFTPMRWAAYQGHKEV 478
                 79****999877777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (504 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       384  (0.0214178); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.61u 0.26s 00:00:00.87 Elapsed: 00:00:00.44
# Mc/sec: 3448.50
//
Query:       EEA22697.1  [L=208]
Description: serine/threonine-protein kinase pef1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.3e-20   72.2   0.0      1e-19   70.9   0.0    1.5  1  Pkinase         Protein kinase domain
    1.7e-07   30.8   0.0    6.2e-07   29.0   0.0    1.7  2  Pkinase_Tyr     Protein tyrosine kinase
  ------ inclusion threshold ------
      0.023   14.0   0.0       0.52    9.6   0.0    2.1  2  Kdo             Lipopolysaccharide kinase (Kdo/WaaP) family
      0.047   12.5   0.0       0.07   11.9   0.0    1.3  1  Pkinase_fungal  Fungal protein kinase


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.9   0.0   2.3e-23     1e-19     106     264 .]       8     186 ..       3     186 .. 0.76

  Alignments for each domain:
  == domain 1  score: 70.9 bits;  conditional E-value: 2.3e-23
                 HHHHHHHHHHHTTEE-SS-SGGGEEEE.TTTE.....EEE-SGTTSEESSSSCS.BCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHH...HHHSS CS
     Pkinase 106 qilegleylHskgiiHrDlKpeNiLid.ekge.....lKitDFGlakelesssk.ltsfvgtseYlAPEvlkeneyskkvDvWslGvilye...lltgk 194
                  +l++l+ lH++g +H D+Kp+NiL++  +ge     +K++  G    ++s+       +gts ++APEv  e +  +++D+WslGv+       +  +
  EEA22697.1   8 VTLKALAVLHENGYVHTDVKPSNILVNyGEGEsrfseVKLAECGGTVSMNSEYArDGIPTGTSLFRAPEVHLEIPWNTAADIWSLGVTSQRdtiCTIPR 106
                 579************************7666689999**************997445679***************************986511133445 PP

                 -STTTSSHHHHHHHHHHT...HHHHHHHCT.......SHH...HHHTTS-HHHHHHHHHHT-SSGCCSTTHHHHHTSGGG CS
     Pkinase 195 ppfsgekgkekvekeldq...lekilkilg.......etkeklpeaseiseeakdllkkllkkdpkkRltaeellqhpyl 264
                  ++++ +g+++    +++    e+   ilg       et + +++++      k+++ k++k dp++R+ta+ell+++++
  EEA22697.1 107 SLYANISGSDRSPFLTRRyadKETQEAILGiipsgevETIQIYRRKDRSVLADKQFVLKMMKLDPRDRPTARELLKDQWF 186
                 5666666665544333333324555556666667664333333333333556699************************8 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.0   0.0   1.4e-10   6.2e-07     114     213 ..      11     116 ..       2     138 .. 0.80
   2 ?   -0.6   0.0      0.14   6.4e+02     236     257 ..     161     182 ..     143     184 .. 0.83

  Alignments for each domain:
  == domain 1  score: 29.0 bits;  conditional E-value: 1.4e-10
                  HHHHHHHHTTEEEST-SGGGEEEEE......TTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSEEEHHHHHHHHHHHHH..HHHTTSS CS
  Pkinase_Tyr 114 kGmeyLeskklvHrdlaarNvLlse......nkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekkftsksDvWsfGvllw..Eiftlge 203
                  k+++ L+++ +vH d+   N+L++        + vk++  G + ++  ++ey +++  +    + apE+  e   ++++D+Ws Gv+     i+t  +
   EEA22697.1  11 KALAVLHENGYVHTDVKPSNILVNYgegesrFSEVKLAECGGTVSM--NSEYARDGIPTGTSLFRAPEVHLEIPWNTAADIWSLGVTSQrdTICTIPR 106
                  68999******************97666655678999999988877..889999999999999***********************965223666666 PP

                  GTTTTSHHHH CS
  Pkinase_Tyr 204 spypglknee 213
                  s y++++ ++
   EEA22697.1 107 SLYANISGSD 116
                  6666665555 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.14
                  HHHHHHT-SSGGGS--HHHHHH CS
  Pkinase_Tyr 236 elmkkcweedpeeRptfselve 257
                  +++ k ++ dp++Rpt +el++
   EEA22697.1 161 QFVLKMMKLDPRDRPTARELLK 182
                  667788999*******999875 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.0   0.00012      0.52     131     160 ..      13      41 ..       2      53 .. 0.83
   2 ?    2.1   0.1     0.023     1e+02       6      26 ..     181     201 ..     176     207 .. 0.84

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00012
         Kdo 131 iaklhragvnHadlyaknillqqeeeeeae 160
                  a lh+ g  H+d+ + nil++ +e +e +
  EEA22697.1  13 LAVLHENGYVHTDVKPSNILVNYGE-GESR 41 
                 5679*****************9997.4444 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.023
         Kdo   6 kqgkvveeaegRrttwfvvae 26 
                 ++ +++ e+ +R ++wf++ e
  EEA22697.1 181 LKDQWFTESSERTVGWFSKEE 201
                 6789*************9876 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   1.6e-05      0.07     316     387 ..      10      79 ..       2      92 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 1.6e-05
  Pkinase_fungal 316 IkghrsLflkagiLHrDiSenNilitdskkegerkglLiDLDlakelsdd...ssesgarertGTleFmaievlk 387
                     +k++  L+ + g++H D+   Nil++      e ++  +++ la   +++   s+ + +++ tGT  F a ev  
      EEA22697.1  10 LKALAVLH-ENGYVHTDVKPSNILVNYG----EGESRFSEVKLAECGGTVsmnSEYARDGIPTGTSLFRAPEVHL 79 
                     688999**.*****************44....444444555555443333000455566999***9999988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (208 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       381  (0.0212505); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.62u 0.35s 00:00:00.97 Elapsed: 00:00:00.58
# Mc/sec: 1088.62
//
Query:       EEA22698.1  [L=443]
Description: hypothetical protein PMAA_093170 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.3e-05   24.2  10.5    3.9e-05   23.5  10.5    1.4  1  PHD            PHD-finger
  ------ inclusion threshold ------
      0.026   15.0   4.1      0.026   15.0   4.1    3.0  3  ZapB           Cell division protein ZapB
      0.032   13.8   5.0       0.18   11.3   1.6    2.2  2  Fzo_mitofusin  fzo-like conserved region
      0.034   14.2   6.9       0.41   10.8   3.8    2.4  2  bZIP_1         bZIP transcription factor
      0.037   13.8  15.6       0.38   10.6   0.1    2.8  2  DivIC          Septum formation initiator
      0.079   13.0  10.6       0.95    9.5   0.1    2.9  2  TMF_DNA_bd     TATA element modulatory factor 1 DNA binding
      0.097   12.5   4.4        0.3   10.9   2.5    2.1  2  Phage_GP20     Phage minor structural protein GP20
       0.12   12.8   2.3        6.9    7.2   0.9    2.6  2  DUF4140        N-terminal domain of unknown function (DUF4140
       0.15   11.7   5.5       0.58    9.7   5.5    1.8  1  PI3K_P85_iSH2  Phosphatidylinositol 3-kinase regulatory subun
       0.25   11.4   4.2       0.19   11.8   0.6    2.2  2  APC_N_CC       Coiled-coil N-terminus of APC, dimerisation do
       0.36   11.0   9.0       0.24   11.5   6.7    1.9  2  Zf_RING        KIAA1045 RING finger
       0.36   11.1   3.3        4.1    7.8   0.1    2.6  2  Lzipper-MIP1   Leucine-zipper of ternary complex factor MIP1
       0.39   10.0   7.0        1.6    8.0   7.0    1.9  1  GAS            Growth-arrest specific micro-tubule binding
        0.4    9.8   7.8        1.9    7.6   7.5    1.9  1  HAP1_N         HAP1 N-terminal conserved region
       0.66   10.0  11.0        7.5    6.6   5.7    2.5  2  TPR_MLP1_2     TPR/MLP1/MLP2-like protein
       0.67   10.2   6.2       0.82    9.9   3.6    2.2  2  Seryl_tRNA_N   Seryl-tRNA synthetase N-terminal domain
          1    9.7   5.3        1.6    9.1   0.4    2.5  2  TSC22          TSC-22/dip/bun family
        1.1    8.9   9.6      0.039   13.5   3.4    1.8  2  PHD_2          PHD-finger
        1.3    9.2   4.9         37    4.5   3.0    2.5  2  Swi5           Swi5
        2.4    8.4   8.4        1.6    9.0   4.9    2.2  2  THOC7          Tho complex subunit 7
          3    6.7   7.0       0.14   11.1   1.4    1.5  2  XRN_M          Xrn1 helical domain
        3.2    8.2  10.5       0.56   10.6   6.2    1.9  1  Fez1           Fez1
        5.6    6.5  10.1        0.2   11.2   3.0    2.3  2  NRBF2          Nuclear receptor-binding factor 2, autophagy r
        6.5    7.1   6.6        4.7    7.5   1.1    2.6  2  HALZ           Homeobox associated leucine zipper


Domain annotation for each model (and alignments):
>> PHD  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5  10.5   5.2e-08   3.9e-05       1      50 [.     123     168 ..     123     170 .. 0.90

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 5.2e-08
                 SBTTTTSTTSTTSCEEEETTTSCEEETTTSSSTHSHHSHHSSTBSSTTTH CS
         PHD   1 rCavCkkksdeeeelvqCdgCkrwfHqkClkppleseekpegewlCekCk 50 
                 +C  C+k    +++lv C++C+++fH +C  p    +e+   +w+C  C 
  EEA22698.1 123 YCMKCRK--AGPKTLVPCNTCSKCFHDECTPPGSLYNERR--QWFCALCV 168
                 6999999..789*********************9977776..5******7 PP

>> ZapB  Cell division protein ZapB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.6       5.8   4.3e+03      38      57 ..     198     217 ..     191     223 .. 0.58
   2 ?    3.4   0.2      0.14   1.1e+02      32      54 ..     328     350 ..     323     363 .. 0.69
   3 ?   15.0   4.1   3.4e-05     0.026      19      67 ..     394     442 ..     383     443 .] 0.91

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 5.8
        ZapB  38 keenreleeeneqlkeerea 57 
                 ++en+  ++ n ++ +++e+
  EEA22698.1 198 SSENNTDQRNNRNMADQQEN 217
                 44555555555555555554 PP

  == domain 2  score: 3.4 bits;  conditional E-value: 0.14
        ZapB  32 eeneelkeenreleeeneqlkee 54 
                 e + +l +++ ele+e+ +l+++
  EEA22698.1 328 ESVTSLRQQIGELESEIVKLRQD 350
                 45566667777777777777665 PP

  == domain 3  score: 15.0 bits;  conditional E-value: 3.4e-05
        ZapB  19 titlLqmeieeLkeeneelkeenreleeeneqlkeereawqerlkkLLg 67 
                 ++++L  + e ++++ne+l++e +  ++e  +  e  ++w+ rl +L+g
  EEA22698.1 394 KVEELTRQAESMRAKNEALEKELKDAKAESAAKDEMLNEWKGRLVSLIG 442
                 7899999999*************************************98 PP

>> Fzo_mitofusin  fzo-like conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   0.1     0.073        54     101     151 ..     307     357 ..     303     364 .. 0.81
   2 ?   11.3   1.6   0.00024      0.18     119     156 ..     383     420 ..     380     423 .. 0.94

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.073
  Fzo_mitofusin 101 stfarlcqqvdetekeleeeikelekeiekleevqkkakllrnkasllese 151
                    s fa l+++vd +   l +e++++++  +++ e++++  +lr+  s+ +++
     EEA22698.1 307 SKFATLSSEVDSALWVLYRELESVTSLRQQIGELESEIVKLRQDVSIRDNQ 357
                    679999999999999999999998888888888888888888776655555 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00024
  Fzo_mitofusin 119 eeikelekeiekleevqkkakllrnkaslleseLekfe 156
                    +ei++l+ + +k+ee++++a+ +r k + le+eL++ +
     EEA22698.1 383 AEIDRLRVQAAKVEELTRQAESMRAKNEALEKELKDAK 420
                    79********************************9986 PP

>> bZIP_1  bZIP transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.1     0.078        59      43      63 ..     331     351 ..     324     352 .. 0.85
   2 ?   10.8   3.8   0.00054      0.41      26      57 ..     393     424 ..     381     430 .. 0.81

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.078
                 HHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  43 ksLkseleelkkevekLkskv 63 
                 +sL+++++el+ e+ kL+++v
  EEA22698.1 331 TSLRQQIGELESEIVKLRQDV 351
                 579999999999999999976 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 0.00054
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
      bZIP_1  26 aeieeLerrvkaLekeNksLkseleelkkeve 57 
                 a++eeL+r+++ + ++N++L +el+  k e++
  EEA22698.1 393 AKVEELTRQAESMRAKNEALEKELKDAKAESA 424
                 68999999999999999999999999988876 PP

>> DivIC  Septum formation initiator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.1    0.0005      0.38       9      39 ..     320     350 ..     317     360 .. 0.88
   2 ?   10.5   5.0   0.00054       0.4      19      56 ..     388     425 ..     381     431 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.0005
                 XXXXXXXXXHHHHHHHHHHHHHHHHHHHHHH CS
       DivIC   9 lifgkkgllaykqlkqeiaalqaelaklkae 39 
                 l+ + + l ++ +l+q+i +l+ e++kl+++
  EEA22698.1 320 LWVLYRELESVTSLRQQIGELESEIVKLRQD 350
                 7889999999999999999999999999997 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00054
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC-XXXXXX CS
       DivIC  19 ykqlkqeiaalqaelaklkaeneeLeaevkdLksdedy 56 
                 ++ + +++++l+++ ++++a+ne+Le+e+kd k + ++
  EEA22698.1 388 LRVQAAKVEELTRQAESMRAKNEALEKELKDAKAESAA 425
                 566889*************************9755444 PP

>> TMF_DNA_bd  TATA element modulatory factor 1 DNA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.1    0.0013      0.95      32      66 ..     327     361 ..     324     369 .. 0.79
   2 ?    4.9   5.8     0.036        27      36      67 ..     403     434 ..     382     439 .. 0.74

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.0013
  TMF_DNA_bd  32 nntikkLrkknkelekeikelkkkleklekeleel 66 
                  +++ +Lr+++ ele+ei +l + ++  + +l   
  EEA22698.1 327 LESVTSLRQQIGELESEIVKLRQDVSIRDNQLILS 361
                 67899****************99888776666555 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.036
  TMF_DNA_bd  36 kkLrkknkelekeikelkkkleklekeleele 67 
                  ++r+kn+ leke+k+ k + + +++ l+e +
  EEA22698.1 403 ESMRAKNEALEKELKDAKAESAAKDEMLNEWK 434
                 57888888888888888888888887777655 PP

>> Phage_GP20  Phage minor structural protein GP20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0      0.52   3.9e+02      15      41 ..     330     358 ..     304     360 .. 0.74
   2 ?   10.9   2.5   0.00041       0.3      38      87 ..     382     427 ..     379     437 .. 0.77

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.52
  Phage_GP20  15 it..kakldeveeerdtlkeqlkdrdkqL 41 
                 +t   +++ e+e+e  +l +++  rd+qL
  EEA22698.1 330 VTslRQQIGELESEIVKLRQDVSIRDNQL 358
                 44456677777777777777777777776 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00041
  Phage_GP20  38 dkqLedLkkkakdneeLqkqieelqaknkkakaeyeakiadlkldnaiel 87 
                 + +++ L  +a  +eeL++q e++ akn++     e++++d k ++a + 
  EEA22698.1 382 QAEIDRLRVQAAKVEELTRQAESMRAKNEA----LEKELKDAKAESAAKD 427
                 568999999999999999999999999999....6666666666665554 PP

>> DUF4140  N-terminal domain of unknown function (DUF4140)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0     0.075        56      65      95 ..     318     358 ..     294     360 .. 0.74
   2 ?    7.2   0.9    0.0093       6.9      46      90 ..     382     425 ..     375     433 .. 0.65

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.075
     DUF4140  65 e.........e.lkalraeleeledelaaledelaaaearl 95 
                 +         e + +lr+++ ele e+ +l+++ +  +++l
  EEA22698.1 318 SalwvlyrelEsVTSLRQQIGELESEIVKLRQDVSIRDNQL 358
                 144555555544999***********999999988777765 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0093
     DUF4140  46 aatildvqvervpnreaeeeelkalraeleeledelaaledelaa 90 
                 +a i  ++v+    +e  ++  +++ra+ e+le+el+++++e aa
  EEA22698.1 382 QAEIDRLRVQAAKVEELTRQ-AESMRAKNEALEKELKDAKAESAA 425
                 45566666666666666665.777777777777777777777666 PP

>> PI3K_P85_iSH2  Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   5.5   0.00077      0.58      18     135 ..     308     440 ..     301     442 .. 0.78

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00077
  PI3K_P85_iSH2  18 klrevskqlqekskeydqlkeeynkiseeiqlkrqaleaFneaikmFeeqiklqekfskeaq............ehEieklq...enleqlksrlk 98 
                    k+  +s+++      + +  e+ ++++++i +    +   +  +++  +q+ l  + ++ a+            ++Ei++l      +e+l+++ +
     EEA22698.1 308 KFATLSSEVDSALWVLYRELESVTSLRQQIGELESEIVKLRQDVSIRDNQLILSRRSMSSAHnntntgmpggisQAEIDRLRvqaAKVEELTRQAE 403
                    666677777777777777777778888888888888888888888888888888888888844455555555559999988622245788999*** PP

  PI3K_P85_iSH2  99 elhsskekLeedlkqqkeeereleReinalkpellqL 135
                    +++++ e Le++lk  k+e+   +  +n+ k  l++L
     EEA22698.1 404 SMRAKNEALEKELKDAKAESAAKDEMLNEWKGRLVSL 440
                    *****************************99999887 PP

>> APC_N_CC  Coiled-coil N-terminus of APC, dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.2       1.2   8.6e+02       6      25 ..     333     352 ..     328     362 .. 0.68
   2 ?   11.8   0.6   0.00025      0.19       3      26 ..     395     418 ..     393     423 .. 0.91

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 1.2
    APC_N_CC   6 LvrQvEaLkkenthlrrELe 25 
                 L +Q+  L  e  +lr+  +
  EEA22698.1 333 LRQQIGELESEIVKLRQDVS 352
                 55777888888888888753 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 0.00025
    APC_N_CC   3 YdQLvrQvEaLkkenthlrrELed 26 
                  + L rQ E +++ n  l +EL+d
  EEA22698.1 395 VEELTRQAESMRAKNEALEKELKD 418
                 5789*******************9 PP

>> Zf_RING  KIAA1045 RING finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   6.7   0.00032      0.24       4      34 ..     120     150 ..     118     165 .. 0.91
   2 ?   -1.8   0.1       4.6   3.4e+03      14      31 ..     156     174 ..     152     175 .. 0.68

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00032
     Zf_RING   4 edelCeiCevytaeelypCRvCtkvfHegCl 34 
                 +d+ C  C     ++l+pC  C+k fH++C 
  EEA22698.1 120 HDDYCMKCRKAGPKTLVPCNTCSKCFHDECT 150
                 6999**************************6 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 4.6
     Zf_RING  14 ytaeelypCRvC.tkvfHe 31 
                 y+ + ++ C +C ++++He
  EEA22698.1 156 YNERRQWFCALCvHRNWHE 174
                 5666777788884467776 PP

>> Lzipper-MIP1  Leucine-zipper of ternary complex factor MIP1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   0.1    0.0054       4.1      52      74 ..     329     351 ..     299     359 .. 0.83
   2 ?    3.1   0.7      0.16   1.2e+02      12      47 ..     394     428 ..     386     440 .. 0.74

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0054
  Lzipper-MIP1  52 kakellkeiallEeevvkLEqkl 74 
                   +++ l++ i  lE e+vkL+q +
    EEA22698.1 329 SVTSLRQQIGELESEIVKLRQDV 351
                   7889999*************998 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.16
  Lzipper-MIP1  12 eveqLqerLqeeeklrraLekalssssdgsllslst 47 
                   +ve+L ++ +  ++ ++aLek l + +++++   + 
    EEA22698.1 394 KVEELTRQAESMRAKNEALEKEL-KDAKAESAAKDE 428
                   7999*******************.444444444444 PP

>> GAS  Growth-arrest specific micro-tubule binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   7.0    0.0022       1.6      54     114 ..     369     429 ..     323     435 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0022
         GAS  54 qenkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkelekelkdlkwehevleqr 114
                 ++n +   p    ++e+++Lr q+++ e+   + ++++a+++ lekelkd k e+  + + 
  EEA22698.1 369 HNNTNTGMPGGISQAEIDRLRVQAAKVEELTRQAESMRAKNEALEKELKDAKAESAAKDEM 429
                 45555555666679999***********************************999887765 PP

>> HAP1_N  HAP1 N-terminal conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   7.5    0.0026       1.9     101     194 ..     329     424 ..     322     430 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0026
      HAP1_N 101 rnekLeeqLesareeiaqlrhelslkddLLqlysdseeeseeeseesee..lreeesleslqklvqldlLqeklreLeeeNekLreeasqLktetd 194
                  + +L +q+++ + ei +lr+++s +d+ L l   s+   +++ ++ ++  + + e   ++ +  +++ L ++ +++   Ne+L +e ++ k e+ 
  EEA22698.1 329 SVTSLRQQIGELESEIVKLRQDVSIRDNQLILSRRSMSSAHNNTNTGMPggISQAEIDRLRVQAAKVEELTRQAESMRAKNEALEKELKDAKAESA 424
                 577899**********************9999888887777777777776577777778999999*******************999988877765 PP

>> TPR_MLP1_2  TPR/MLP1/MLP2-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.2     0.017        12      56      96 ..     327     367 ..     324     374 .. 0.82
   2 ?    6.6   5.7      0.01       7.5      57      98 ..     393     434 ..     381     441 .. 0.55

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.017
  TPR_MLP1_2  56 vkelqalreelnelkaeiaelkaeaesakaeleeseeswee 96 
                 ++++++lr+++ el++ei +l++++    ++l  s+ s+++
  EEA22698.1 327 LESVTSLRQQIGELESEIVKLRQDVSIRDNQLILSRRSMSS 367
                 67889999999999999999999999888888877777665 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.01
  TPR_MLP1_2  57 kelqalreelnelkaeiaelkaeaesakaeleeseesweeqk 98 
                  ++++l  ++++++a+ + l++e+++akae +++ e ++e k
  EEA22698.1 393 AKVEELTRQAESMRAKNEALEKELKDAKAESAAKDEMLNEWK 434
                 344455555555555555555555555555555555555555 PP

>> Seryl_tRNA_N  Seryl-tRNA synthetase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0       1.6   1.2e+03      67      90 ..     328     351 ..     306     360 .. 0.66
   2 ?    9.9   3.6    0.0011      0.82      24      76 ..     381     433 ..     378     436 .. 0.90

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 1.6
                   S-TCCCCCCCHHHHHHHHHHHHHH CS
  Seryl_tRNA_N  67 edaeeliaevkelkeelkaleael 90 
                   e  ++l++++ el  e+ +l +++
    EEA22698.1 328 ESVTSLRQQIGELESEIVKLRQDV 351
                   455555666666666666555555 PP

  == domain 2  score: 9.9 bits;  conditional E-value: 0.0011
                   CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCTTS-TCCCCCCC CS
  Seryl_tRNA_N  24 dkadvdelleldekrrelqveleelqaerNelskeIgkakkkkedaeeliaev 76 
                   ++a++d+l    +k +el  ++e+++a+  +l ke + ak++ + ++e+++e 
    EEA22698.1 381 SQAEIDRLRVQAAKVEELTRQAESMRAKNEALEKELKDAKAESAAKDEMLNEW 433
                   578899999999******************************99999988876 PP

>> TSC22  TSC-22/dip/bun family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.4    0.0021       1.6      14      37 ..     328     351 ..     324     360 .. 0.90
   2 ?    2.1   0.6      0.33   2.5e+02      22      43 ..     394     415 ..     382     430 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0021
       TSC22  14 EeVevLkekIkeLeernseleeEN 37 
                 E V  L+++I eLe+++ +l+++ 
  EEA22698.1 328 ESVTSLRQQIGELESEIVKLRQDV 351
                 7899***************99875 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.33
       TSC22  22 kIkeLeernseleeENslLkal 43 
                 k+ eL+ + + ++  N+ L + 
  EEA22698.1 394 KVEELTRQAESMRAKNEALEKE 415
                 5778888888888888877655 PP

>> PHD_2  PHD-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.4       6.5   4.8e+03      31      35 ..     123     127 ..     120     128 .. 0.64
   2 ?   13.5   3.4   5.3e-05     0.039       4      35 ..     135     167 ..     132     168 .. 0.80

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 6.5
       PHD_2  31 lCrrC 35 
                 +C +C
  EEA22698.1 123 YCMKC 127
                 45555 PP

  == domain 2  score: 13.5 bits;  conditional E-value: 5.3e-05
       PHD_2   4 llsCdkCsvaVHasCYGvskesdgee.WlCrrC 35 
                 l+ C+ Cs ++H +C +  +   +   W C+ C
  EEA22698.1 135 LVPCNTCSKCFHDECTPPGSLYNERRqWFCALC 167
                 899************977665544334****** PP

>> Swi5  Swi5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.0      0.07        52       4      30 ..     329     355 ..     327     389 .. 0.80
   2 ?    4.5   3.0      0.05        37       3      35 ..     393     424 ..     391     434 .. 0.75

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.07
                 HHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        Swi5   4 eikeleeqleelekelaelkeelkekk 30 
                 ++ +l++q+ ele+e+ +l++    ++
  EEA22698.1 329 SVTSLRQQIGELESEIVKLRQDVSIRD 355
                 678899999999999999999887765 PP

  == domain 2  score: 4.5 bits;  conditional E-value: 0.05
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHH CS
        Swi5   3 aeikeleeqleelekelaelkeelkekkdpeet 35 
                 a+++el +q e+++++ ++l++elk+ k +e  
  EEA22698.1 393 AKVEELTRQAESMRAKNEALEKELKDAK-AESA 424
                 6789999999999999999999999765.3333 PP

>> THOC7  Tho complex subunit 7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.1       1.4     1e+03      84     103 ..     330     349 ..     306     363 .. 0.60
   2 ?    9.0   4.9    0.0021       1.6      74     111 ..     392     429 ..     380     434 .. 0.85

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 1.4
       THOC7  84 ieavreeieelkaqLeeara 103
                   ++r++i el++++ + r+
  EEA22698.1 330 VTSLRQQIGELESEIVKLRQ 349
                 33334444444443333333 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.0021
       THOC7  74 eaekeeieseieavreeieelkaqLeearatranrkey 111
                 +a+ ee+ +++e++r+++e+l+++L++a+a+ a + e 
  EEA22698.1 392 AAKVEELTRQAESMRAKNEALEKELKDAKAESAAKDEM 429
                 46778999************************999885 PP

>> XRN_M  Xrn1 helical domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   0.4         7   5.3e+03     104     112 ..     204     212 ..     190     241 .. 0.42
   2 ?   11.1   1.4   0.00018      0.14      61     167 ..     326     429 ..     309     437 .. 0.65

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 7
       XRN_M 104 daaneeaav 112
                 d+ n++++ 
  EEA22698.1 204 DQRNNRNMA 212
                 111111111 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00018
       XRN_M  61 kldrveklvslvgkveekifrkrkeredrkekklakeeeaskedaaneeaavaeeklseskvaksaeaeaeaeaeaeaeakaekekrekaekeleesee 159
                 +l+ v  l +++g+ e++i + r++   r ++ + +++++s++   n++++ +   +s++++++   ++a++ +e++ +a++++ k+e  ekel++ + 
  EEA22698.1 326 ELESVTSLRQQIGELESEIVKLRQDVSIRDNQLILSRRSMSSA--HNNTNTGMPGGISQAEIDRL-RVQAAKVEELTRQAESMRAKNEALEKELKDAKA 421
                 7999********************9998888877766554433..33333333445555566543.333333344444555555555666666666666 PP

       XRN_M 160 eeeeeDkv 167
                 e + +D++
  EEA22698.1 422 ESAAKDEM 429
                 66666654 PP

>> Fez1  Fez1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   6.2   0.00075      0.56      63     154 ..     311     426 ..     300     436 .. 0.63

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00075
        Fez1  63 ektlelevcenelqrkkseaellrekvekleeelkelreelselsleeeeaa.........................lesdeakaqrqe....aeelee 132
                 + + e++     l r+ ++++ lr+++++le+e+ +lr+++s   ++   ++                         l+ ++a     +    ++++e+
  EEA22698.1 311 TLSSEVDSALWVLYRELESVTSLRQQIGELESEIVKLRQDVSIRDNQLILSRrsmssahnntntgmpggisqaeidrLRVQAA-----KveelTRQAES 404
                 445555555556777899999******************98885544333336666677777777777765533333333333.....13344466777 PP

        Fez1 133 lkreverlraeLkeerqkkeeq 154
                 ++++ e l++eLk  + ++ ++
  EEA22698.1 405 MRAKNEALEKELKDAKAESAAK 426
                 7777777777887766655444 PP

>> NRBF2  Nuclear receptor-binding factor 2, autophagy regulator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.6       4.3   3.2e+03       9      38 ..      43      72 ..      29      79 .. 0.65
   2 ?   11.2   3.0   0.00027       0.2      78     117 ..     385     424 ..     322     432 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 4.3
       NRBF2  9 hlqasakpsaeeaegqsapasqklspskek 38
                +l++ + +  + a g+++pa q+++ps+++
  EEA22698.1 43 RLESASTARKSTASGRNTPARQNQEPSQGQ 72
                455555556666667777777777777665 PP

  == domain 2  score: 11.2 bits;  conditional E-value: 0.00027
       NRBF2  78 ktkleeqatkiadLkrlvelLlaenerLrkenkqLkaeka 117
                   +l  qa k+++L r  e++ a ne+L ke k  kae a
  EEA22698.1 385 IDRLRVQAAKVEELTRQAESMRAKNEALEKELKDAKAESA 424
                 457888*******************************987 PP

>> HALZ  Homeobox associated leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.1      0.35   2.6e+02      20      40 ..     329     349 ..     322     352 .. 0.82
   2 ?    7.5   1.1    0.0063       4.7      15      37 ..     396     418 ..     392     423 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.35
        HALZ  20 dydsLkkenekLkaelqeLke 40 
                 ++ sL+++  +L++e+ +L++
  EEA22698.1 329 SVTSLRQQIGELESEIVKLRQ 349
                 55699999999*****99986 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0063
        HALZ  15 daLksdydsLkkenekLkaelqe 37 
                 + L+ + +s+++ ne+L++el+ 
  EEA22698.1 396 EELTRQAESMRAKNEALEKELKD 418
                 78999***************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (443 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1531  (0.0853924); expected 358.6 (0.02)
Passed bias filter:                      685  (0.0382063); expected 358.6 (0.02)
Passed Vit filter:                       130  (0.00725082); expected 17.9 (0.001)
Passed Fwd filter:                        36  (0.00200792); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              24  [number of targets reported over threshold]
# CPU time: 0.87u 0.39s 00:00:01.26 Elapsed: 00:00:00.58
# Mc/sec: 2300.40
//
Query:       EEA22699.1  [L=720]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.6e-36  122.9   0.4    3.7e-35  120.6   0.4    2.0  1  AdoMet_MTase  Predicted AdoMet-dependent methyltransferase


Domain annotation for each model (and alignments):
>> AdoMet_MTase  Predicted AdoMet-dependent methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  120.6   0.4   2.1e-39   3.7e-35       5     111 ..     348     472 ..     344     473 .. 0.87

  Alignments for each domain:
  == domain 1  score: 120.6 bits;  conditional E-value: 2.1e-39
  AdoMet_MTase   5 ekyndlykelkqkyakrlvenwvestdplkfvfedlaiaaylivlwkktrse..................eketsfvdvgcgngllvyvlaaegykg 83 
                   +  +++y+ lk  y++ l ++wve+t+p k+vfedlai+a+li+lw++ +                     +   fvd+ cgng+lvyvl++egykg
    EEA22699.1 348 HMVQNTYTRLKTTYSQDLCKRWVENTEPSKHVFEDLAITAFLIELWRNMYGVipraeqtkqedeeggrdgSEFEGFVDIACGNGVLVYVLLMEGYKG 444
                   56789*****************************************98765555555666777777766445678********************** PP

  AdoMet_MTase  84 ygidlrkrklwelypaevkvdliekvvv 111
                   +g+d+r+rk+w+++p +v+ +l e + +
    EEA22699.1 445 WGFDARRRKTWSIFPEWVQENLEEAIYI 472
                   *********************9987655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (720 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       413  (0.0230353); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.64u 0.34s 00:00:00.98 Elapsed: 00:00:00.51
# Mc/sec: 4274.97
//
Query:       EEA22700.1  [L=1184]
Description: structural maintenance of chromosome complex subunit SmcA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.6e-22   80.0   0.0    3.4e-22   79.0   0.0    1.6  1  SMC_N          RecF/RecN/SMC N terminal domain
    1.1e-20   75.0   0.2    1.1e-20   75.0   0.2    5.2  2  AAA_23         AAA domain
    1.3e-13   51.4   0.1    6.6e-07   29.4   1.1    3.9  2  AAA_15         AAA ATPase domain
     0.0002   21.3   7.1      0.012   15.4   0.0    3.1  3  AAA_21         AAA domain, putative AbiEii toxin, Type IV TA 
    0.00029   20.5   0.0    0.00061   19.5   0.0    1.5  1  AAA_29         P-loop containing region of AAA domain
     0.0037   16.2  14.1     0.0037   16.2  14.1    5.2  6  Spc7           Spc7 kinetochore protein
  ------ inclusion threshold ------
      0.011   15.4   0.0      0.011   15.4   0.0    4.4  6  AAA_27         AAA domain
      0.021   15.2  14.1       0.91   10.0   0.1    5.5  5  NPV_P10        Nucleopolyhedrovirus P10 protein
       0.09   12.3   0.6       0.61    9.6   0.0    2.6  2  AAA_25         AAA domain
       0.14   12.6   1.0       0.58   10.6   1.0    2.1  1  Chrome_Resist  Chromate resistance exported protein
       0.25    9.7   8.0        1.2    7.5   0.3    2.6  3  Hemagglutinin  Haemagglutinin
        0.3   11.3   0.0        0.3   11.3   0.0    5.8  6  Fib_alpha      Fibrinogen alpha/beta chain family


Domain annotation for each model (and alignments):
>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.0   0.0   2.3e-25   3.4e-22       2     179 ..      98    1090 ..      97    1097 .. 0.98

  Alignments for each domain:
  == domain 1  score: 79.0 bits;  conditional E-value: 2.3e-25
                  EEEEEEESETTEECEEEEEETTSSEEEEEESTTSSHHHHHHHHHHHCTT.TTTTTTCHCCCCCC--BTTCSSTTEEEEEEEEEETTEESSSSSSCEE CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N    2 lkrleienFksyagktvilpfsksftaivGpNGSGKsnlldAilFvLGersakklrseklsdlihkskekasvkkaeveitfdnedkklkiekeevs 98  
                  + r+++++F +y  ++v+ +f +++++i+GpNG GKs l+ Ai+  LG   ++  r++++s+ +++      +k+a +ei +       +  k++ +
  EEA22700.1   98 IVRMKLKDFVTY--TNVEYHFGSQLNMIIGPNGTGKSTLVCAICLGLGWGPQHLGRAKDASEFVKH-----GAKEAIIEIELARG----PPFKTNPV 183 
                  67899*******..79********************************98886669999***9998.....77888888854333....44566777 PP

                  EEEEEETTSE.EEEEETTEEE-HHHHHHHHHCTT-STT........................................................... CS
                  xxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx........................................................... RF
       SMC_N   99 isrrvkrkge.seykingkevtkkevsellesagiske........................................................... 135 
                  i+r +k +g+ s+++i+gke+t+k+v++l ++  i+++                                                           
  EEA22700.1  184 IRRVIKFEGNkSTFFIDGKEATRKQVMKLNQKFSIQIDnlcqflpqdkvsefaaltpiellnstqraaagpqmiewhddlkrlraeqkklladnkgd 280 
                  77776655544************************************************************************************** PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA22700.1  281 rdvlanlesrqesqradvervreraqikrrieileyarpmaaykdqvpkwkairdrkhqletefkelkaevapmlvavngkqeyfgrtddlvkfkrr 377 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA22700.1  378 evaaaehaakeiaarldghdetmknltrqidsekkegstykqqlstvqqsinritrqmedkpeefdidaynekiralqreikdienrareikegrka 474 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA22700.1  475 vferleekkhrindtenelrslqsqsgqreamlkkfspdthrayrwilenkdkfdktvygpaliecsvndskyadaiesllqkndflafttqsikdf 571 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA22700.1  572 rtlqkalnvelklhdvsirncttplsdlrppvsdgemrdlgfdgwakdylsgpepviamlcneqflfrtplvlreindqeysrmeshnainswvagk 668 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA22700.1  669 qtykvnrrkeygpgatstqvrqvrparfwtdkpldvslkqelldtksqlegemaeiektieslrlelkvsgdqhtqkkreksqleeekaekqtalvn 765 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA22700.1  766 fralpeklsqeqikkrevekhfdglrervlairgkqdqvalekaetaiayadavetfrkvhhdliqaeirniealsdfenlkarneeirqtleqkqn 862 
                  ************************************************************************************************* PP

                  ................................................................................................. CS
                  ................................................................................................. RF
       SMC_N  136 ................................................................................................. 135 
                                                                                                                   
  EEA22700.1  863 evkeanikqkeaaeegrrlkeearglldnassepdklealesdyfkqlttdqleadiesekarlelthevgeglvkefedrqraidklrdkmasyqt 959 
                  ************************************************************************************************* PP

                  .......................................................................................CS-HHHHHHH CS
                  .......................................................................................xxxxxxxxxx RF
       SMC_N  136 .......................................................................................lLSgGektLv 145 
                                                                                                           SgGe++++
  EEA22700.1  960 klndfenaiqeirnkweprldtlvktisdafsdsfarigcagqvtvdkvedepglngepggsdfdqwsiqiqvkfretenlsvldshRQSGGERAVS 1056
                  ***************************************************************************************99******** PP

                  HHHHHHHHHCCS--SEEEECTTTTTS-HHHHHHH CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N  146 alaLlfAiqkvkpaplyllDeidaaLDeknvkkv 179 
                   +  l+A+q+ + +p+ ++Dei++ +D +n + v
  EEA22700.1 1057 TIFYLMALQSLSASPFRVVDEINQGMDPRNERMV 1090
                  *****************************98877 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.0   0.2   7.3e-24   1.1e-20       1     192 [.     100     311 ..     100     350 .. 0.77
   2 ?   -0.3  19.5      0.87   1.3e+03     106     197 ..     402     498 ..     320     500 .. 0.63

  Alignments for each domain:
  == domain 1  score: 75.0 bits;  conditional E-value: 7.3e-24
      AAA_23   1 kLkienfrsfrdqeidFskgltlItGpNGaGKTTildAiklaLygetprlsrks......grgfeksdveiese.........gkvkayveltfenkdg 84 
                 ++k++ f  + ++e +F++ l+ I+GpNG+GK+T+++Ai+l+L+  ++ l+r +      +     +  + +            k+++++++ ++ +++
  EEA22700.1 100 RMKLKDFVTYTNVEYHFGSQLNMIIGPNGTGKSTLVCAICLGLGWGPQHLGRAKdasefvK-----HGAKEAIIeielargppFKTNPVIRRVIKFEGN 193
                 689****************************************999999999886444443.....444422222335588999999******999999 PP

      AAA_23  85 rytrsiererelskkkgkttkkaklelleideleqfisellgskkiil.nlilflgqer....feefelkdkkerleeleke.leeledekkllekleq 177
                 ++t +i  + +++  k    k +++++++id+l+qf+++   s+++ l ++ l+   +r     +++e+ d+++rl++ +k+ l +++ +++ l +le 
  EEA22700.1 194 KSTFFI--DGKEATRKQ-VMKLNQKFSIQIDNLCQFLPQDKVSEFAALtPIELLNSTQRaaagPQMIEWHDDLKRLRAEQKKlLADNKGDRDVLANLES 289
                 753333..444444433.3466678899***********999999988566666666779999779999999999998655527788889999999986 PP

      AAA_23 178 ekekek.......eleeleeel 192
                 ++e +        e  ++++++
  EEA22700.1 290 RQESQRadvervrERAQIKRRI 311
                 6665555555555555555544 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.87
      AAA_23 106 kaklelleideleqfisellgskkiilnlilflgqerfeefelkdkkerleelekeleeledekkllekl.....eqekekekeleeleeeleeilk 197
                 + ++++ ++++   + +++l+  ++++n+i  + +++ eef+  + +e++++l++e++++e++++++++      e+++ek+ ++++ e+el ++++
  EEA22700.1 402 NLTRQIDSEKKEGSTYKQQLSTVQQSINRITRQMEDKPEEFDIDAYNEKIRALQREIKDIENRAREIKEGrkavfERLEEKKHRINDTENELRSLQS 498
                 1111222222222333333333333444444444555555556666779999999999999999999988888877777788888888888887765 PP

>> AAA_15  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.4   1.1   4.4e-10   6.6e-07       3     261 ..      98     505 ..      97     539 .. 0.62
   2 !   14.6   0.0   1.4e-05      0.02      42     272 ..     550     983 ..     517    1103 .. 0.51

  Alignments for each domain:
  == domain 1  score: 29.4 bits;  conditional E-value: 4.4e-10
      AAA_15   3 IkkikikNFRslkdveidlseeltvliGkNnsGKSsilealdlFlnnkekkn.............................................kk 56 
                 I ++k+k F  + +ve ++ ++l+ +iG+N++GKS+++ a+ l l    + +                                             k+
  EEA22700.1  98 IVRMKLKDFVTYTNVEYHFGSQLNMIIGPNGTGKSTLVCAICLGLGWGPQ-HlgrakdasefvkhgakeaiieielargppfktnpvirrvikfegnKS 195
                 6778999999*******************************777776633.247777889999999**************9999999999998888877 PP

      AAA_15  57 vikiekedleifeniseskdikIdvef..........................................................aekekakeyektlk 97 
                 +++i+ ++   ++  + ++++ I++                                                            +     ++   ++ 
  EEA22700.1 196 TFFIDGKEATRKQVMKLNQKFSIQIDNlcqflpqdkvsefaaltpiellnstqraaagpqmiewhddlkrlraeqkklladnkgdR-----DVLANLES 289
                 7888888888888888888888887779999**99988888888888888888888888888888888888777776666444330.....33333333 PP

      AAA_15  98 skekkkadlllkkkesdlkktikdkklklkknelsdekisvekkkskkelpkekeeklekekeelkidkedlkklikkleeslkkee............ 184
                 ++e++ ad++  +++ ++k +i+  +++ +          ++++  k++    +++ le+e +elk +   +    +  +e++   +            
  EEA22700.1 290 RQESQRADVERVRERAQIKRRIEILEYARP-------MAAYKDQVPKWKAIRDRKHQLETEFKELKAEVAPMLVAVNGKQEYFGRTDdlvkfkrrevaa 381
                 333334444444444444444444443332.......22222222333333333333333333333333333333332222222222455555555666 PP

      AAA_15 185 ............................elknvlksaiiklllisakRnvsdedsekkssllgklkekileealqekl....................e 235
                                             e+k+    +++++ + ++ + ++ + ++k +++ + +++++++  lq +                      
  EEA22700.1 382 aehaakeiaarldghdetmknltrqidsEKKEGSTYKQQLSTVQQSINRITRQMEDKPEEFDIDAYNEKIRA-LQREIkdienrareikegrkavferL 479
                 666655555555555554444444444444555567777777777777777777777777777777777664.44444466667666666666666555 PP

      AAA_15 236 eelteklkeiqeklkeidkklaeelk 261
                 ee++  +++++++l+ ++++ +++++
  EEA22700.1 480 EEKKHRINDTENELRSLQSQSGQREA 505
                 55555666666666666665555444 PP

  == domain 2  score: 14.6 bits;  conditional E-value: 1.4e-05
      AAA_15  42 aldlFlnnkekknkkvikiekedleifeniseskdikIdvef......................................................... 83 
                 a++ +l++     ++++ +  +++++f+  ++  +++++++                                                          
  EEA22700.1 550 AIESLLQK-----NDFLAFTTQSIKDFRTLQKALNVELKLHDvsirncttplsdlrppvsdgemrdlgfdgwakdylsgpepviamlcneqflfrtplv 643
                 55555552.....46666666666666666777777777666777777777777777777777777777777777777777777777777777777777 PP

      AAA_15  84 ..............................................aekekakeyektlkskekkkadlllkkkesdlkktikdkklklkknelsdeki 136
                                                               +            ++ + + ++ l   ++++l +t+ + + +  ++e++ e+ 
  EEA22700.1 644 lreindqeysrmeshnainswvagkqtykvnrrkeygpgatstqvrQ-----------VRPARFWTDKPLDVSLKQELLDTKSQLEGEMAEIEKTIESL 731
                 77777777777777777777777777776666554444433333330...........33333444444444444444444444444444444444444 PP

      AAA_15 137 svekkkskkelpkekeeklekekeelkid..kedlkklikkleeslkkee...............................................el 186
                  +e k s  ++  +k+ek+++e+e+ +++    + + l +kl++   k+                                                + 
  EEA22700.1 732 RLELKVSGDQHTQKKREKSQLEEEKAEKQtaLVNFRALPEKLSQEQIKKRevekhfdglrervlairgkqdqvalekaetaiayadavetfrkvhhdL- 829
                 44444443333333333333333333222222222222222222211111233344444444444444444433333333333333665555433331. PP

      AAA_15 187 knvlksaiiklllisakRnvsdedsekkssllgklkekileealqekl................................................... 234
                    ++++i+ ++  s+  n  + ++e+++ +l++++++ +e ++++k                                                    
  EEA22700.1 830 ---IQAEIRNIEALSDFEN-LKARNEEIRQTLEQKQNEVKEANIKQKEaaeegrrlkeearglldnassepdklealesdyfkqlttdqleadieseka 924
                 ...2222222222222111.1233333333333333333333332222333333445555555555555555555566666666666666777777777 PP

      AAA_15 235 ......................eeelteklkeiqeklkeidkklaeelkkilkkkidkik 272
                                       +++l++k  + q+kl+++++ ++e  + + ++ +d+++
  EEA22700.1 925 rlelthevgeglvkefedrqraIDKLRDKMASYQTKLNDFENAIQEIRN-KWEPRLDTLV 983
                 7777777777766666666666555555555555555555555533333.2333333333 PP

>> AAA_21  AAA domain, putative AbiEii toxin, Type IV TA system
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   8.3e-06     0.012       1      19 [.     120     138 ..     120     175 .. 0.88
   2 ?   -2.1   0.4       1.8   2.7e+03     137     202 ..     472     531 ..     416     588 .. 0.51
   3 !    8.8   0.4   0.00083       1.2      68     276 ..     849    1088 ..     818    1123 .. 0.69

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 8.3e-06
      AAA_21   1 lnvliGpNgsGKSnLLdal 19 
                 ln++iGpNg+GKS+L  a+
  EEA22700.1 120 LNMIIGPNGTGKSTLVCAI 138
                 79************97766 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.8
      AAA_21 137 dlqfgkaltditsrawsllllldglrkerigllnifadyfgfakekrllqrlvrslklveielsdl 202
                 ++  +++l + ++r+++++ +l      r+++ +  ++++  +k  + + r +r ++++ ++ +++
  EEA22700.1 472 RKAVFERLEEKKHRINDTENEL------RSLQSQSGQREAMLKKFSPDTHRAYRWILENKDKFDKT 531
                 2333333333333333333333......44444444444444444444444444444444444444 PP

  == domain 3  score: 8.8 bits;  conditional E-value: 0.00083
      AAA_21   68 qgvryryglrlersqveeklssvetllesgllldkrsleeedvfnpeargirggvsvfslkelsvsepndlqfgkaltditsrawsllllldglrke 164 
                  ++ ++r  l+++++ v+e  + +++  e g  l+++++   d+ ++e++   +++s+   +  +   + d +++ka++++t++  + l    + r +
  EEA22700.1  849 RNEEIRQTLEQKQNEVKEANIKQKEAAEEGRRLKEEARGLLDNASSEPDKLEALESDYFKQLTTDQLEADIESEKARLELTHEVGEGLVKEFEDRQR 945 
                  4555566666666666777777777777777777777777777777777777777777777777777777777777777777777777776655443 PP

      AAA_21  165 ..rigllnifadyfgfakekrllqrlvrslklveielsdlgegeeliasvderlrer.....................................gvv 222 
                    ++++  +       a+ ++ l ++++ +++++++++  ++  ++  s ++ +  +                                      v 
  EEA22700.1  946 aiDKLRDKM-------ASYQTKLNDFENAIQEIRNKWEPRLDTLVKTISDAFSD--SfarigcagqvtvdkvedepglngepggsdfdqwsiqiQVK 1033
                  332222222.......33344444444444444444444444444433333333..244899999999***********************999999 PP

      AAA_21  223 flengdgqelparelSdGtkrll.alltallralkkgsllliDEpEngLHPkllr 276 
                  f e ++   l+++  S G + +   ++++ l+ l+ +++ ++DE+  g++P+  r
  EEA22700.1 1034 FRETENLSVLDSHRQSGGERAVStIFYLMALQSLSASPFRVVDEINQGMDPRNER 1088
                  999999999999**********867777777777777**************7544 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0   4.1e-07   0.00061       3      42 ..     100     138 ..      98     142 .. 0.85

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 4.1e-07
      AAA_29   3 rlqlvNWgtfdghtieidlkgatlltGpsGsGKSTllDAi 42 
                 r++l +  t+++ ++++  +   +++Gp+G+GKSTl+ Ai
  EEA22700.1 100 RMKLKDFVTYTNVEYHFGSQ-LNMIIGPNGTGKSTLVCAI 138
                 77888888999999999855.69*************9887 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   6.3       1.2   1.9e+03     196     250 ..     257     311 ..     213     354 .. 0.64
   2 ?   -3.7   6.9       2.8   4.2e+03     148     200 ..     263     315 ..     257     389 .. 0.43
   3 !   16.2  14.1   2.5e-06    0.0037     138     260 ..     387     510 ..     382     519 .. 0.94
   4 ?   -3.0  18.4       1.7   2.6e+03     139     272 ..     705     838 ..     701     847 .. 0.82
   5 ?   -5.1  16.8       7.5   1.1e+04     142     248 ..     781     890 ..     774     911 .. 0.75
   6 ?   -2.7  16.9       1.4   2.1e+03     138     253 ..     851     971 ..     851     992 .. 0.71

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 1.2
        Spc7 196 id.keeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeei 250
                 i+ +++L+ lr e ++l a+ +  ++ la+l+++ e++++++e ++e +++++ +i
  EEA22700.1 257 IEwHDDLKRLRAEQKKLLADNKGDRDVLANLESRQESQRADVERVRE-RAQIKRRI 311
                 44566666666666666666666666666666666666666666633.33333333 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 2.8
        Spc7 148 legleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkee 200
                 l+ l++++++L ++++   ++l +le+++++ ++ +e+ +e+a+    i+  e
  EEA22700.1 263 LKRLRAEQKKLLADNKGDRDVLANLESRQESQRADVERVRERAQIKRRIEILE 315
                 33334444444444444444444444444444444444444333322222222 PP

  == domain 3  score: 16.2 bits;  conditional E-value: 2.5e-06
        Spc7 138 egLkegleenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesid.keeLeelreelaelkaeieekkkelaelqeqleeleek 235
                 +++  +l+ + e++++  ++++++++e ++++++l++ ++++++  ++++++ ee++    +e++++l++e++++++  +e k+  + + e+lee++ +
  EEA22700.1 387 KEIAARLDGHDETMKNLTRQIDSEKKEGSTYKQQLSTVQQSINRITRQMEDKPEEFDIDAyNEKIRALQREIKDIENRAREIKEGRKAVFERLEEKKHR 485
                 678899999*********************************************9987768************************************** PP

        Spc7 236 ieelkeqkseleeeiaeaervleec 260
                 i++++++ ++l+++  + e +l++ 
  EEA22700.1 486 INDTENELRSLQSQSGQREAMLKKF 510
                 ****************999999875 PP

  == domain 4  score: -3.0 bits;  conditional E-value: 1.7
        Spc7 139 gLkegleenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeelesidkeeLeelreelaelkaeieekkkelaelqeqleeleekie 237
                 +Lk++l ++ ++le + +++ek  e l   l+    ++++ ++e  +l+e+++e ++    + ++l e+l++ + + +e +k  + l+e++ +++ k +
  EEA22700.1 705 SLKQELLDTKSQLEGEMAEIEKTIESLRLELKVSGDQHTQKKREKSQLEEEKAE-KQTALVNFRALPEKLSQEQIKKREVEKHFDGLRERVLAIRGKQD 802
                 689999999999999999999999999999999999999999999999998887.67778888888899999999999999999999999999999999 PP

        Spc7 238 elkeqkseleeeiaea.ervleeckgwsesevsrlk 272
                 +++ +k+e+  + a a e +++ +++  + e+++++
  EEA22700.1 803 QVALEKAETAIAYADAvETFRKVHHDLIQAEIRNIE 838
                 999999888877776535556666666666766655 PP

  == domain 5  score: -5.1 bits;  conditional E-value: 7.5
        Spc7 142 egleenlegleedkelLekqeeeldellpeleeekaeleeeleklqe..aaeelesid.keeLeelreelaelkaeieekkkelaelqeqleeleekie 237
                  ++e++++gl+e    +  +++++   + e+   +a+  e+++k      ++e+ +i+   + e+l+ + +e+ +++e+k++e++e + + +e +e+  
  EEA22700.1 781 REVEKHFDGLRERVLAIRGKQDQVALEKAETAIAYADAVETFRKVHHdlIQAEIRNIEaLSDFENLKARNEEIRQTLEQKQNEVKEANIKQKEAAEEGR 879
                 467888888888888888888888777777777777666666666665566778888878889999999999999999999999999988888888888 PP

        Spc7 238 elkeqkselee 248
                  lke+ + l +
  EEA22700.1 880 RLKEEARGLLD 890
                 88877766655 PP

  == domain 6  score: -2.7 bits;  conditional E-value: 1.4
        Spc7 138 egLkegleenlegleedkelLekqeeeldellpeleeekaeleeeleklqe.....aaeelesid.keeLeelreelaelkaeieekkkelaelqeqle 230
                 e+++++le++ ++++e + + ++  ee  +l++e +   ++ ++e +kl++     + ++l++ + ++++e+ + +l+  ++  e + ke +++q+ ++
  EEA22700.1 851 EEIRQTLEQKQNEVKEANIKQKEAAEEGRRLKEEARGLLDNASSEPDKLEAlesdyF-KQLTTDQlEADIESEKARLELTHEVGEGLVKEFEDRQRAID 948
                 689999999999999999999999999999999999999999999999999755531.22333333445555666666666666666666666666666 PP

        Spc7 231 eleekieelkeqkseleeeiaea 253
                 +l++k+++ +++ +++e++i+e 
  EEA22700.1 949 KLRDKMASYQTKLNDFENAIQEI 971
                 66666666666666666666653 PP

>> AAA_27  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.4   0.0   7.2e-06     0.011       3      46 ..      98     138 ..      97     148 .. 0.91
   2 ?   -1.5   0.5         1   1.5e+03     158     198 ..     259     299 ..     248     307 .. 0.71
   3 ?   -3.2   0.9       3.5   5.3e+03     150     200 ..     381     431 ..     377     437 .. 0.70
   4 ?   -0.2   1.3      0.42   6.2e+02     155     198 ..     458     501 ..     449     510 .. 0.70
   5 ?   -2.8   0.9       2.6   3.8e+03     155     196 ..     721     762 ..     717     777 .. 0.71
   6 ?   -1.8   0.5       1.3   1.9e+03     169     204 ..     850     871 ..     789     896 .. 0.66

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 7.2e-06
      AAA_27   3 lerLdLeryGkftdrsldfsaeeadlhliyGpNEAGKstalrAi 46 
                 + r++L+ +  +t+ + +f+   ++l +i+GpN +GKst++ Ai
  EEA22700.1  98 IVRMKLKDFVTYTNVEYHFG---SQLNMIIGPNGTGKSTLVCAI 138
                 67899**************8...89***************9997 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1
      AAA_27 158 lrevleaLeaeadelfkprkskkrainealeeleeakkelr 198
                  ++ l++L+ae+++l +++k  +  +++ +++ e++++ ++
  EEA22700.1 259 WHDDLKRLRAEQKKLLADNKGDRDVLANLESRQESQRADVE 299
                 456789999******99999999777777777666666555 PP

  == domain 3  score: -3.2 bits;  conditional E-value: 3.5
      AAA_27 150 easaGlaslrevleaLeaeadelfkprkskkrainealeeleeakkelrea 200
                 +a+ + +++++ l+  ++ +++l ++  s+k++  + +++l+++++++++ 
  EEA22700.1 381 AAEHAAKEIAARLDGHDETMKNLTRQIDSEKKEGSTYKQQLSTVQQSINRI 431
                 556666777777777777888888887777777777777777777777654 PP

  == domain 4  score: -0.2 bits;  conditional E-value: 0.42
      AAA_27 155 laslrevleaLeaeadelfkprkskkrainealeeleeakkelr 198
                 ++++++   ++++ ++++f++ ++kk++in++++el++++++  
  EEA22700.1 458 IKDIENRAREIKEGRKAVFERLEEKKHRINDTENELRSLQSQSG 501
                 45666777777778888888877777788888888877776654 PP

  == domain 5  score: -2.8 bits;  conditional E-value: 2.6
      AAA_27 155 laslrevleaLeaeadelfkprkskkrainealeeleeakke 196
                 +a++++++e+L+ e +   +++++kkr+  + +ee +e +++
  EEA22700.1 721 MAEIEKTIESLRLELKVSGDQHTQKKREKSQLEEEKAEKQTA 762
                 567788888888888888888888886666666555555544 PP

  == domain 6  score: -1.8 bits;  conditional E-value: 1.3
      AAA_27 169 adelfkprkskkrainealeeleeakkelreaqvra 204
                  +e+               ++le+ ++e++ea++++
  EEA22700.1 850 NEEIR--------------QTLEQKQNEVKEANIKQ 871
                 22222..............22223333333333322 PP

>> NPV_P10  Nucleopolyhedrovirus P10 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.5      0.32   4.7e+02      40      59 ..     389     408 ..     369     441 .. 0.55
   2 ?    7.7   0.7    0.0032       4.8      17      62 ..     418     462 ..     415     463 .. 0.86
   3 ?   10.0   0.1   0.00061      0.91      12      59 ..     443     494 ..     441     500 .. 0.74
   4 ?    1.2   0.8      0.35   5.2e+02      21      60 ..     828     866 ..     816     871 .. 0.85
   5 ?    6.9   0.1    0.0059       8.8      27      63 ..     937     973 ..     918     988 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.32
     NPV_P10  40 lnekLdaqsaqLaeletkve 59 
                 + ++Ld+  +++++l  +++
  EEA22700.1 389 IAARLDGHDETMKNLTRQID 408
                 55555555555555544333 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0032
     NPV_P10  17 ddkVdalqqqvddvqenlpdvtelnekLdaqsaqLaeletkvenIq 62 
                 +++++ +qq++++++ +++d +  +  +da ++++ +l+ ++++I+
  EEA22700.1 418 KQQLSTVQQSINRITRQMED-KPEEFDIDAYNEKIRALQREIKDIE 462
                 6899999*******999999.5566789999999999999999997 PP

  == domain 3  score: 10.0 bits;  conditional E-value: 0.00061
     NPV_P10  12 dikavddkVdalqqqvddvqenlpdvte....lnekLdaqsaqLaeletkve 59 
                 di a ++k+ alq +++d+++  ++++e    + e+L++    +++ e+++ 
  EEA22700.1 443 DIDAYNEKIRALQREIKDIENRAREIKEgrkaVFERLEEKKHRINDTENELR 494
                 899*******************999985333345566666666666665555 PP

  == domain 4  score: 1.2 bits;  conditional E-value: 0.35
     NPV_P10  21 dalqqqvddvqenlpdvtelnekLdaqsaqLaeletkven 60 
                 d +q+++ ++++ l d+++l+++ +++ ++L++ +++v++
  EEA22700.1 828 DLIQAEIRNIEA-LSDFENLKARNEEIRQTLEQKQNEVKE 866
                 568999999988.9999**************999999975 PP

  == domain 5  score: 6.9 bits;  conditional E-value: 0.0059
     NPV_P10  27 vddvqenlpdvtelnekLdaqsaqLaeletkvenIqd 63 
                 v++ ++  + +++l +k+ + +++L+++e+++++I +
  EEA22700.1 937 VKEFEDRQRAIDKLRDKMASYQTKLNDFENAIQEIRN 973
                 6777788888999999999999999999999999976 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.0   0.00041      0.61      34      56 ..     119     141 ..     112     160 .. 0.86
   2 ?   -1.4   0.2         1   1.5e+03      80     135 ..     784     839 ..     782     847 .. 0.60

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00041
      AAA_25  34 elallaGapgtGKttlaldlala 56 
                  l++++G+ gtGK+tl++ ++l 
  EEA22700.1 119 QLNMIIGPNGTGKSTLVCAICLG 141
                 6899**************99875 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 1
      AAA_25  80 EdsedelrrRlravgeal...rddarllvldlagv.eslpLfakdrggtlltadvdalea 135
                 E   d+lr+R+ a++ ++   ++ + ++++ +a+  e     + + ++ l++a+++++ea
  EEA22700.1 784 EKHFDGLRERVLAIRGKQdqvALEKAETAIAYADAvET----FRKVHHDLIQAEIRNIEA 839
                 7788999*******988844533333333333443222....234455566777777665 PP

>> Chrome_Resist  Chromate resistance exported protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   1.0   0.00039      0.58      35     121 ..     817     902 ..     807     913 .. 0.85

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00039
  Chrome_Resist  35 aevpkeeaipFDiegaelthegerctFevllkkfeledpaLkrlaeivraadvkeeaklapeaagleailaglseelkddeelleaa 121
                    ++v++  ++++D+ +ae++  +  + Fe l ++ e   ++L++  + v++a++k ++++a+e + l+  ++gl  +++++ ++lea 
     EEA22700.1 817 DAVETFRKVHHDLIQAEIRNIEALSDFENLKARNEEIRQTLEQKQNEVKEANIK-QKEAAEEGRRLKEEARGLLDNASSEPDKLEAL 902
                    345555789*********************************************.7******************9999988888764 PP

>> Hemagglutinin  Haemagglutinin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   0.3   0.00079       1.2     338     410 ..     393     470 ..     383     494 .. 0.75
   2 ?   -3.5   0.7       1.6   2.5e+03     372     424 ..     818     869 ..     807     883 .. 0.78
   3 ?    6.7   0.0    0.0014       2.1     357     420 ..     931     994 ..     927     999 .. 0.91

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.00079
                    BXSEBTTXXSXSEEEEEEETTEEEEEEXHHHHHHHHHHHHHHHHHH.....HHHTTTEEEBXSSXXTTTTHHHHHHHH CS
  Hemagglutinin 338 leGGweGmidGwyGyhssneqGsavaadkkstqeainkitkkvnsl.....iekenkqleavgkelnelekrieeldk 410
                    l+G  e m +      s+ ++Gs++   + + q++in+it++++       i+  n +++a+ +e+ ++e+r  e+++
     EEA22700.1 393 LDGHDETMKNLTRQIDSEKKEGSTYKQQLSTVQQSINRITRQMEDKpeefdIDAYNEKIRALQREIKDIENRAREIKE 470
                    555555666666666788999********************9986422222566677777777777777777766654 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 1.6
                    HHHHHHHHHHHHHHHTTTEEEBXSSXXTTTTHHHHHHHHHHHHHHHHHHHHHH CS
  Hemagglutinin 372 ainkitkkvnsliekenkqleavgkelnelekrieeldkkvddgfldvityni 424
                    a++   k    li+ e +++ea++ ++++l+ r ee+ + ++    +v   ni
     EEA22700.1 818 AVETFRKVHHDLIQAEIRNIEALS-DFENLKARNEEIRQTLEQKQNEVKEANI 869
                    566666666678888999999997.6889999999998888888777766665 PP

  == domain 3  score: 6.7 bits;  conditional E-value: 0.0014
                    TTEEEEEEXHHHHHHHHHHHHHHHHHHHHHTTTEEEBXSSXXTTTTHHHHHHHHHHHHHHHHHH CS
  Hemagglutinin 357 eqGsavaadkkstqeainkitkkvnsliekenkqleavgkelnelekrieeldkkvddgfldvi 420
                    e G ++  + +  q+ai+k+ +k+ s   k n   +a+ +  n+ e r++ l k + d f d +
     EEA22700.1 931 EVGEGLVKEFEDRQRAIDKLRDKMASYQTKLNDFENAIQEIRNKWEPRLDTLVKTISDAFSDSF 994
                    5678888889999*****************999889999999******************9976 PP

>> Fib_alpha  Fibrinogen alpha/beta chain family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   2.8     0.095   1.4e+02      27     125 ..     334     435 ..     330     441 .. 0.72
   2 ?    7.1   2.3    0.0038       5.6      33      92 ..     447     506 ..     444     510 .. 0.86
   3 ?   -2.3   4.4       3.1   4.7e+03      30      69 ..     721     760 ..     701     814 .. 0.52
   4 ?   -3.1   5.3       5.5   8.3e+03      43     129 ..     772     861 ..     759     874 .. 0.53
   5 ?    0.1   2.1      0.58   8.6e+02      33      72 ..     846     885 ..     839     927 .. 0.53
   6 ?   11.3   0.0    0.0002       0.3      24      71 ..     934     981 ..     929     995 .. 0.88

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.095
                 CCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH...HHHHCCHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  27 lkyekdvkkdlekleneleeisnstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilrlk...etidaqesnirvLqnvlesneqkiqkLe 122
                  + +++++++ ++l+ e++ +    +  +e+  +++d ++ k ++ +  +++ k+++ +l+ + +++k   ++id++ ++    ++ l++ +q+i+++ 
  EEA22700.1 334 RDRKHQLETEFKELKAEVAPMLVAVNGKQEYFGRTDDLVKFKRREVAAAEHAAKEIAARLDGHDETMKnltRQIDSEKKEGSTYKQQLSTVQQSINRIT 432
                 566778888888999999999999999999999999999988888888899999999999866555541114566666666667777777777777666 PP

                 HHH CS
   Fib_alpha 123 qdi 125
                  ++
  EEA22700.1 433 RQM 435
                 555 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0038
                 CCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH CS
   Fib_alpha  33 vkkdlekleneleeisnstkeaeelvkeikdslrekqkskkdndnvikksskeleeeilr 92 
                 ++++++ l++e+++i+n+ +e++e  k++ + l+ek++  +d++n +++++++  ++ + 
  EEA22700.1 447 YNEKIRALQREIKDIENRAREIKEGRKAVFERLEEKKHRINDTENELRSLQSQSGQREAM 506
                 5789*************************************9999999888876655555 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 3.1
                 CCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  30 ekdvkkdlekleneleeisnstkeaeelvkeikdslrekq 69 
                   +++k++e+l+ el+   +++++ ++  +++++  +ekq
  EEA22700.1 721 MAEIEKTIESLRLELKVSGDQHTQKKREKSQLEEEKAEKQ 760
                 2222233333333333333333222222222222222222 PP

  == domain 4  score: -3.1 bits;  conditional E-value: 5.5
                 CCCCCCCHHHHHHHHHHHHHHHH...HHHHHHHHHH.HHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHH..HHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  43 eleeisnstkeaeelvkeikdsl...rekqkskkdn.dnvikksskeleeeilrlketidaqesnirvLqn..vlesneqkiqkLeqdidqke 129
                 +l++ + +++e+e++   +++ +   r kq + + +  ++   +++ +e+     ++ i+a+++ni++L +  +l++ +++i   +q  +qk+
  EEA22700.1 772 KLSQEQIKKREVEKHFDGLRERVlaiRGKQDQVALEkAETAIAYADAVETFRKVHHDLIQAEIRNIEALSDfeNLKARNEEI---RQTLEQKQ 861
                 5555555555555555555553211122332222223566667777788555555666666668888887511333333333...33333333 PP

  == domain 5  score: 0.1 bits;  conditional E-value: 0.58
                 CCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  33 vkkdlekleneleeisnstkeaeelvkeikdslrekqksk 72 
                 +k + e+++++le+ +n+ kea+   ke  +  r+ ++++
  EEA22700.1 846 LKARNEEIRQTLEQKQNEVKEANIKQKEAAEEGRRLKEEA 885
                 4444455555555555555555555444444433333333 PP

  == domain 6  score: 11.3 bits;  conditional E-value: 0.0002
                 HCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH CS
   Fib_alpha  24 dlllkyekdvkkdlekleneleeisnstkeaeelvkeikdslrekqks 71 
                 + l k  +d ++ ++kl++++++++ + ++ e+ ++ei+++++++  +
  EEA22700.1 934 EGLVKEFEDRQRAIDKLRDKMASYQTKLNDFENAIQEIRNKWEPRLDT 981
                 56788999999*******************************998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1184 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2175  (0.121312); expected 358.6 (0.02)
Passed bias filter:                      614  (0.0342462); expected 358.6 (0.02)
Passed Vit filter:                       142  (0.00792013); expected 17.9 (0.001)
Passed Fwd filter:                        68  (0.00379274); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 1.96u 0.36s 00:00:02.31 Elapsed: 00:00:00.69
# Mc/sec: 5140.25
//
Query:       EEA22701.1  [L=105]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
     0.0012   18.9   0.4     0.0013   18.7   0.4    1.1  1  Ax_dynein_light  Axonemal dynein light chain
     0.0085   15.4   0.8     0.0092   15.3   0.8    1.0  1  HemX             HemX, putative uroporphyrinogen-III C-methyl
  ------ inclusion threshold ------
      0.035   14.5   0.4      0.071   13.5   0.4    1.4  1  COX7a            Cytochrome c oxidase subunit VII
      0.048   14.4   0.5      0.064   14.0   0.5    1.2  1  HWE_HK           HWE histidine kinase
      0.062   13.6   3.2      0.084   13.2   3.2    1.3  1  DUF5082          Domain of unknown function (DUF5082)
        3.7    8.2   6.7         18    6.0   0.6    2.2  2  MerR-DNA-bind    MerR, DNA binding


Domain annotation for each model (and alignments):
>> Ax_dynein_light  Axonemal dynein light chain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.4   4.3e-07    0.0013     111     161 ..      40      90 ..      12      96 .. 0.85

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 4.3e-07
  Ax_dynein_light 111 mrkalqaeqgkselekkikeLeeekeelekqvaelkaklealekrekerrq 161
                       +k+l ++++++ +++ki++L++ +  l ++ ++++++l +le+r +er +
       EEA22701.1  40 QKKKLAQKEHEATFDEKIQALQTARGILVSKKNTVEKQLHELEERIAERAR 90 
                      5788999999************************************99976 PP

>> HemX  HemX, putative uroporphyrinogen-III C-methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.8   3.1e-06    0.0092       9      79 ..      17      89 ..       9     101 .. 0.68

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 3.1e-06
        HemX  9 llallvalavgaglyy..lgqqqvqeltaev...aelqqqlaaleqqlaqveaekeqkqeleerlqqlaekleale 79
                  a +v + +g++ly   l+ +q++++ a++   a+ +++++al+++ +    + ++k+++e++l++l+e++++++
  EEA22701.1 17 YTAAAVTITIGGSLYGaeLATKQQKKKLAQKeheATFDEKIQALQTARGI---LVSKKNTVEKQLHELEERIAERA 89
                56889999999996641133334334444443568889999999999988...66666667777777777776655 PP

>> COX7a  Cytochrome c oxidase subunit VII
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.4   2.4e-05     0.071      24      47 ..       9      33 ..       7      34 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.4e-05
       COX7a 24 rsklylypy.yalfavgllgslygm 47
                ++k+++y y  a+ +++++gslyg+
  EEA22701.1  9 KRKIWMYVYtAAAVTITIGGSLYGA 33
                679******999***********96 PP

>> HWE_HK  HWE histidine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.5   2.2e-05     0.064      17      67 ..      36      87 ..      33      98 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 2.2e-05
                HHHHSSSXS-HHHHHHHHHHHHHHHHHHHHH.HHHCTTS-EEHHHHHHHHHH CS
      HWE_HK 17 arqtlrsaesleefaeklsgRLqALsaahdl.lsreewagaeLaelleeela 67
                a++  +++  ++e ++++++ +qAL  a  + +s+++  + +L+el e+  +
  EEA22701.1 36 ATKQQKKKLAQKEHEATFDEKIQALQTARGIlVSKKNTVEKQLHELEERIAE 87
                55666777888999****************9345667778899999776655 PP

>> DUF5082  Domain of unknown function (DUF5082)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   3.2   2.8e-05     0.084       9      56 ..      41      87 ..      33     100 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 2.8e-05
     DUF5082  9 qaqiaelrseiaaleekIerLkeaktklsdekeslkqkkkklekplns 56
                +++ a++++e a+ +ekI+ L++a+  l+++k++++++ ++le+ +++
  EEA22701.1 41 KKKLAQKEHE-ATFDEKIQALQTARGILVSKKNTVEKQLHELEERIAE 87
                3444555554.578***********************99999988766 PP

>> MerR-DNA-bind  MerR, DNA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.8    0.0064        19      39      61 ..      44      66 ..      29      70 .. 0.70
   2 ?    6.0   0.6     0.006        18      39      54 ..      72      87 ..      68      90 .. 0.85

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0064
                   HHHHHHHHHHHHHHHHHHHHHHH CS
  MerR-DNA-bind 39 allarklaeleeriaeLqalrae 61
                      +++ a  +e+i++Lq  r  
     EEA22701.1 44 LAQKEHEATFDEKIQALQTARGI 66
                   3346788999********99865 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.006
                   HHHHHHHHHHHHHHHH CS
  MerR-DNA-bind 39 allarklaeleeriae 54
                   + ++++l+eleeriae
     EEA22701.1 72 NTVEKQLHELEERIAE 87
                   56899*********98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (105 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1660  (0.0925874); expected 358.6 (0.02)
Passed bias filter:                      730  (0.0407162); expected 358.6 (0.02)
Passed Vit filter:                        94  (0.0052429); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 712.35
//
Query:       EEA22702.1  [L=1117]
Description: lipase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.3e-18   66.4   0.0    2.7e-16   59.7   0.0    2.5  1  Lipase_3       Lipase (class 3)
  ------ inclusion threshold ------
      0.015   15.9   2.7      0.037   14.6   0.1    2.6  3  Abhydrolase_6  Alpha/beta hydrolase family
       0.03   13.6   0.0      0.056   12.7   0.0    1.3  1  Hydrolase_4    Serine aminopeptidase, S33


Domain annotation for each model (and alignments):
>> Lipase_3  Lipase (class 3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.7   0.0   4.5e-20   2.7e-16       1     138 [.     784     953 ..     784     956 .. 0.93

  Alignments for each domain:
  == domain 1  score: 59.7 bits;  conditional E-value: 4.5e-20
                 EEEE----------------EEE-HHHH-GTT-EEEHHHHHHHH...S-HHHHHHHHHHHHHHHTT-EEEEEEEETHHHHHHHHHHHHHHHTT-SS... CS
    Lipase_3   1 vvafRGtesakdwltdldfslteakellekeggkvhsgfleaye...eslreqvlkelkrllekypeysivvtGHSLGgalAlLaaldlvengene... 93 
                 v+a+RGt   +d+ltd+++   +++ + +  + kvh+g+  +++   e   + v +++k  le++p+y ++++GHSLGg++A+L+a+++ + +  +   
  EEA22702.1 784 VLALRGTWGFEDILTDMTCDYDDLEWQGK--NWKVHKGMHASAKrllEGGGKRVMATIKAALEEFPDYGVIFCGHSLGGGVAALLATMISQPNADTsgp 880
                 789*****************999998754..9************666666789*************************************9998889** PP

                 ................................---EEEEEES----B-HHHHHHHHT-TTEEEEEEEETT--GGG-S CS
    Lipase_3  94 ................................kkkvtvvtfGqPrvgnkefaklvdsqlnkkvlrvvntnDivPrlp 138
                                                 ++++ v++fG P +++  ++++ +      v++vvn nD+vP+l+
  EEA22702.1 881 sfvtasalqatkplllttnhqqeaaktfslppNRPIHVYAFGPPACMSPFLRRATR---GL-VTTVVNGNDVVPTLS 953
                 ***************************************************99999...45.788*********986 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.1      0.15   8.8e+02      51      81 ..      86     123 ..      62     214 .. 0.63
   2 ?   -2.9   0.0       1.5   8.7e+03      42      60 ..     291     308 ..     269     402 .. 0.74
   3 ?   14.6   0.1   6.2e-06     0.037      51      97 ..     837     912 ..     756    1040 .. 0.62

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.15
                    HHHHHHHCCTT..TTSEEEEEETCH..HH..........HHHH CS
  Abhydrolase_6  51 adlaalldelaagggpvvlvGHSlG..Ga..........lala 81 
                    a ++a+l++    g+   + GHS+G  G           la++
     EEA22702.1  86 AVVEAILTRA---GR--DVSGHSQGdyGRseadsilersLAAL 123
                    2224444444...44..56******555477776666553333 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.5
                    GCS--HHHCHHHHHHHCCT CS
  Abhydrolase_6  42 pppldledladlaalldel 60 
                    +pp+++++  d+ +l de 
     EEA22702.1 291 SPPHSWDP-SDVQQLTDED 308
                    56677766.6665555554 PP

  == domain 3  score: 14.6 bits;  conditional E-value: 6.2e-06
                    HHHHHHHCCTT..TTSEEEEEETCHHHHHHHHHHCC................EE.EEES-..................... CS
  Abhydrolase_6  51 adlaalldelaagggpvvlvGHSlGGalalaaapla..............lvvg.vlldp...................pp 97 
                    a++ a+l+e++  +  v+  GHSlGG +a++   la              +v +  l ++                   pp
     EEA22702.1 837 ATIKAALEEFP--DYGVIFCGHSLGGGVAAL---LAtmisqpnadtsgpsFVTAsALQATkplllttnhqqeaaktfslPP 912
                    66667777776..8999**********9999...66333666664444442222122222333333333333333333322 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   9.3e-06     0.056      66     124 ..     839     895 ..     834     919 .. 0.66

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 9.3e-06
  Hydrolase_4  66 vekvkeehpelplfllGhSmGGliallyllrypdkvaglilsaPalkikaklkappllk 124
                  ++++ ee p+  ++ +GhS+GG +a+l++++ ++    +  s+P +  ++ l+a++ l 
   EEA22702.1 839 IKAALEEFPDYGVIFCGHSLGGGVAALLATMISQ--PNADTSGPSFVTASALQATKPLL 895
                  67788999********************965555..33445555555554444333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1117 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       584  (0.0325729); expected 358.6 (0.02)
Passed bias filter:                      353  (0.0196888); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.80u 0.32s 00:00:01.12 Elapsed: 00:00:00.47
# Mc/sec: 7154.03
//
Query:       EEA22703.1  [L=121]
Description: oxidoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    7.4e-36  123.9   0.9    8.5e-36  123.7   0.9    1.0  1  FMN_dh        FMN-dependent dehydrogenase
    1.4e-05   24.4   0.2    1.9e-05   24.0   0.2    1.1  1  Glu_synthase  Conserved region in glutamate synthase
    2.1e-05   23.7   0.9    3.2e-05   23.1   1.0    1.3  1  IMPDH         IMP dehydrogenase / GMP reductase domain
     0.0093   15.4   0.3      0.019   14.4   0.1    1.5  2  His_biosynth  Histidine biosynthesis protein
  ------ inclusion threshold ------
       0.01   15.0   0.0      0.014   14.5   0.0    1.1  1  IGPS          Indole-3-glycerol phosphate synthase
      0.018   14.3   0.2      0.025   13.9   0.2    1.1  1  ThiG          Thiazole biosynthesis protein ThiG
       0.07   12.5   0.4      0.073   12.5   0.4    1.1  1  NMO           Nitronate monooxygenase
       0.07   12.3   0.2      0.091   12.0   0.2    1.1  1  DHO_dh        Dihydroorotate dehydrogenase


Domain annotation for each model (and alignments):
>> FMN_dh  FMN-dependent dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.7   0.9   3.8e-39   8.5e-36     250     347 ..      12     109 ..      10     110 .. 0.98

  Alignments for each domain:
  == domain 1  score: 123.7 bits;  conditional E-value: 3.8e-39
                 SSTT---HHHCHHHHHHHH..SS-EEEESS--SHHHHHHHHHTT-SEEEESHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT-SBHHHHHCGGEE CS
      FMN_dh 250 qldgapatidvLpeiveavggrievlvDgGirrGsDvlkAlalGAdavllGRpflyglaagGeeGvervleilraelertmallGvksvaeldrslls 347
                 +ldga+ +++vLpeiveavg++++vl+D+Gir+G+D++kA+alGA+av++GRp++yg  ++G+eG+++vl+ l a++  +ma++G+ s+a+++r++l+
  EEA22703.1  12 ELDGAIGSLEVLPEIVEAVGKDMTVLFDSGIRTGADIVKAIALGAKAVFVGRPVMYGYGINGKEGAKEVLQGLLADFYLSMAIAGIPSIADCRREVLR 109
                 69********************************************************************************************9987 PP

>> Glu_synthase  Conserved region in glutamate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.0   0.2   8.6e-09   1.9e-05     272     311 ..      31      70 ..      22      73 .. 0.87

  Alignments for each domain:
  == domain 1  score: 24.0 bits;  conditional E-value: 8.6e-09
                   GGG-EEEEESS--SHHHHHHHHHHT-SEEE-SHHHHHHTT CS
  Glu_synthase 272 rdrvsliadGglktgadvvkalalGAdavgigtaalialg 311
                    + +++  d g++tgad+vka+alGA av +g+  +   g
    EEA22703.1  31 GKDMTVLFDSGIRTGADIVKAIALGAKAVFVGRPVMYGYG 70 
                   5677888999***********************9997665 PP

>> IMPDH  IMP dehydrogenase / GMP reductase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.1   1.0   1.4e-08   3.2e-05     205     238 ..      31      64 ..      17      97 .. 0.83

  Alignments for each domain:
  == domain 1  score: 23.1 bits;  conditional E-value: 1.4e-08
                 TCT-EEEEES---SHHHHHHHHHTT-SEEEESCC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       IMPDH 205 kagvpviaDGGikysgdivkAlaaGadavmlGsl 238
                  ++++v+ D Gi++  divkA+a+Ga+av +G+ 
  EEA22703.1  31 GKDMTVLFDSGIRTGADIVKAIALGAKAVFVGRP 64 
                 46799***************************84 PP

>> His_biosynth  Histidine biosynthesis protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.1   8.4e-06     0.019      51     103 ..      13      63 ..       5      68 .. 0.82
   2 ?   -0.6   0.0      0.34   7.6e+02      75      93 ..      64      82 ..      61     104 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 8.4e-06
                   HHHHCTTHHHHHHHHHHHHHH-SSEEEEESSSSSHHHHHHHHHCT-SEEEESH CS
  His_biosynth  51 ldaakegreanldlveeiaeevfipvqvGGGIrsledveelleagadkviigt 103
                   ld+a  + e+  ++ve++ +   ++v  ++GIr+  d+ +++ +ga+ v +g 
    EEA22703.1  13 LDGAIGSLEVLPEIVEAVGKD--MTVLFDSGIRTGADIVKAIALGAKAVFVGR 63 
                   677776666666677776666..99999*********************9985 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.34
                  EEEEESSSSSHHHHHHHHH CS
  His_biosynth 75 pvqvGGGIrsledveelle 93
                  pv+ G GI+  e ++e+l+
    EEA22703.1 64 PVMYGYGINGKEGAKEVLQ 82
                  8999999999999999987 PP

>> IGPS  Indole-3-glycerol phosphate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.0   6.4e-06     0.014     198     242 ..      22      66 ..      16      72 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 6.4e-06
                 HHHHHCHCC-TTSEEEEESSS-SHHHHHHHCCTT-SEEEESHHHH CS
        IGPS 198 tteeLaklvpkdvllvaeSGiktredveklkeegvnafLvGeslm 242
                    e+++ v kd+++   SGi+t +d+ k  + g++a+ vG  +m
  EEA22703.1  22 VLPEIVEAVGKDMTVLFDSGIRTGADIVKAIALGAKAVFVGRPVM 66 
                 5567889999*******************************9998 PP

>> ThiG  Thiazole biosynthesis protein ThiG
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.2   1.1e-05     0.025     166     206 ..      22      64 ..      12      69 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.1e-05
                 HHHHHHHH-..SS-BEEES---SHHHHHHHHHTT-SEEEESHH CS
        ThiG 166 alkiiieea..kvPvivDAGigspsdaaqamelGadavllnta 206
                 +l  i+e +  ++ v+ D Gi++  d+++a+ lGa+av++   
  EEA22703.1  22 VLPEIVEAVgkDMTVLFDSGIRTGADIVKAIALGAKAVFVGRP 64 
                 56667777666899************************99765 PP

>> NMO  Nitronate monooxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.4   3.2e-05     0.073     179     223 ..      17      63 ..       8      99 .. 0.87

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 3.2e-05
         NMO 179 kglfaLvpqvldavd..iPviAaGGiidrrgvaaaLalGAsgvqigt 223
                  g ++++p++++av   + v+   Gi ++ ++  a+alGA++v +g 
  EEA22703.1  17 IGSLEVLPEIVEAVGkdMTVLFDSGIRTGADIVKAIALGAKAVFVGR 63 
                 67899*********778***************************996 PP

>> DHO_dh  Dihydroorotate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.2   4.1e-05     0.091     230     279 ..      19      68 ..      17      87 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 4.1e-05
                 HHHHHHHHHHHTTT.S-EEEESS--SHHHHHHHHHHTECEEEESHHHHHH CS
      DHO_dh 230 alkvirelykrlkkeipiIgvGGiesgeDalekieaGAslvqvytalvfe 279
                 +l+v+ e+ + + k++ ++   Gi +g D +  i  GA +v v+  +++ 
  EEA22703.1  19 SLEVLPEIVEAVGKDMTVLFDSGIRTGADIVKAIALGAKAVFVGRPVMYG 68 
                 6899999************************************9988774 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (121 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       275  (0.0153383); expected 358.6 (0.02)
Passed bias filter:                      250  (0.0139439); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.44u 0.30s 00:00:00.74 Elapsed: 00:00:00.47
# Mc/sec: 778.54
//
Query:       EEA22704.1  [L=246]
Description: FMN dependent dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-48  165.8   0.0    1.5e-48  165.6   0.0    1.0  1  FMN_dh    FMN-dependent dehydrogenase


Domain annotation for each model (and alignments):
>> FMN_dh  FMN-dependent dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  165.6   0.0   8.5e-53   1.5e-48       1     167 [.      36     203 ..      36     241 .. 0.87

  Alignments for each domain:
  == domain 1  score: 165.6 bits;  conditional E-value: 8.5e-53
                 HHCCS-HHHHHHHH--STTSHHHHHHHHGGGGEEE---SSSS-SS-B--EEETTEEESSSEEE--BSTGGGTSTTHHHHHHHHHHHHTS-EEEETT-SS CS
      FMN_dh   1 ArkrlpkkafayvaggagdevtlrenraaferirlrprvlrdvskvdlsttllGqklslPvliaPvglaklahpdgelalaraaakagipfvlstvast 99 
                 Ar+ ++ + f+y+aggag+++t+++nr af++++l  ++l++++ vd+s++l+G+k+++P+l+aPvg++ lah+d+e  la+a+a+ ++p++lst++ +
  EEA22704.1  36 ARNVMSLRSFSYIAGGAGEKATMDSNRLAFRQWKLISKMLKSTE-VDTSIELFGEKYPHPILMAPVGVQALAHRDKETGLAQACAEVDVPYILSTASGS 133
                 7889999*********************************9875.6***************************************************** PP

                 -HHHHHHHHT.T-EEEEEE-CSSHHHHHHHHHHHHHCTESEEEEESSTSS---BHHHHHCT-.-BSTT-T CS
      FMN_dh 100 sleevaaaae.gplwfqlyvpkdrelteellkraeaagykalvltvDtpvlgkRerdlrngf.slppklk 167
                 s+e+vaa+ + g +w+qly+p d+++t +llkra+a gykalv+t+Dt++l +R +dl++g+  +  +++
  EEA22704.1 134 SFEDVAASCGdGAKWYQLYWPIDNDITVSLLKRAKANGYKALVVTLDTWTLAWRPADLDTGYlPFLAGIG 203
                 *******64427***********************************************98734444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (246 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       370  (0.020637); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 1771.47
//
Query:       EEA22705.1  [L=566]
Description: repressible acid phosphatase precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    6.2e-35  121.3   0.0    8.1e-35  120.9   0.0    1.2  1  His_Phos_2  Histidine phosphatase superfamily (branch 2)


Domain annotation for each model (and alignments):
>> His_Phos_2  Histidine phosphatase superfamily (branch 2)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  120.9   0.0   4.5e-39   8.1e-35       2     381 ..     119     483 ..     118     485 .. 0.83

  Alignments for each domain:
  == domain 1  score: 120.9 bits;  conditional E-value: 4.5e-39
                 EEEEEEEEE--SBB-SHHHHHHHHHHHHHHHH.........HHCHHTGCCGGGGT............--SSSTTS.B-HHHHHHHHHHHHHHHHHCHTC CS
  His_Phos_2   2 LksvvvviRHGdRtPkqkvkksvtspiflsllkkhkeKlkqlktalekkghfpgtyrkv...eveklqlilkwggelthaGrkqaeelGrqfrqrYplg 97 
                 +++v++++RHG+R+P+++     +++++++        lk l + l + ++f+++   +   ++e+ + +l   g    aG    ++ G +fr+rY  +
  EEA22705.1 119 VEQVHMLSRHGERYPTKTAG--SRHLALVER-------LKRLDIPLNGSLSFFNDGWAYftdNPEQDFEQLTSTG--PYAGTLGSFTTGVRFRTRYG-H 205
                 79*****************8..455555444.......578************9875557855555555555555..88999***************.7 PP

                 CHTTSS--TTEEEEEESSHHHHHHHHHHHHHHCHCCC---S-TTSTTGGG-TTTTCCCEEEHHHHCCCCHHCTTSHHTCHHHC.HHHTGGHCHHHHCHC CS
  His_Phos_2  98 LlrlhltykdlkirassegRviaSAaafakGllglegeltdllskdkdllddsnaakdlldeakkklkelltegaeacpafew.pikvakrvdelvkyl 195
                 Ll++     ++  +as+++Rvi++A +fa Gl+g             d  +   a++d+++e  +++++ lt+g  +c ++ + +++    + + ++++
  EEA22705.1 206 LLPKPG--LKMRLWASDSKRVIDTARYFAAGLFGISI----------DWERNDIAEVDVIPETLDRGTDTLTPGG-TCVRYIEdVVHGHDHGRNMLAEF 291
                 777633..69***********************6666..........777777889*******************.88888877999999999999999 PP

                 CCCCHHHHH.....HHCHHHCTTEEEE-HHHHHHHHHHHHHHHHHHCT-TTGGGCTH..HCHHHHHHHHHHHHHHHC........TTTCCCCHHHHHHH CS
  His_Phos_2 196 kedmdenia.....krleqlcpgesnllakerwdklercfyeknkfdiskicdlydemkydalhnrylkdleelyklakvipqEygigpeeklkiGlll 289
                 +  + ++ia     ++++q      +++  e++++ e+c +e+ +++ s++c ++++   d+ h++y  dl ++y+         g+g+  + ++G l+
  EEA22705.1 292 QTAYIPPIArrlidEEMNQV---VGEFTTLEIYAMQEMCGFETLARGSSPWCGVFTS--RDWDHFEYARDLIHFYRA--------GPGNRYAGAMGWLW 377
                 99999999944444444444...5579******************************..******************........************** PP

                 HHHHHHHHCTSSSEECCS......CCCECS-SEEEEEE-HHHHHHHHHHCTTTTTBTTB.SSS......TTT..HCCCS-CT-EEEEEEEEE...TCTT CS
  His_Phos_2 290 lnpllkkilndlqrtree......atperhvrlrlyfthdshiysllnaLglpeelagedslaa.....ldrlsaspelpymsqivfelyed...ssek 374
                 ln+    ++  ++   +        t   +  + + + hd +i+++l+aL ++++ +  + l +      + +++s+++p++++i+fe+ ++    + +
  EEA22705.1 378 LNATSHLLEAGPDLGTMFfslyvsLTLFLKFVVDACSVHDGDIAPMLTALHIFDDPKYGNHLPVthiaeDRVWKTSTVMPMGGRITFERLRCgesIEGQ 476
                 *********99888884455665555555555556678************88886666656666799*9999********************7543333 PP

                 TEEEEEE CS
  His_Phos_2 375 kfyvrll 381
                 + +vr+ 
  EEA22705.1 477 DLFVRIN 483
                 4888875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (566 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       263  (0.014669); expected 358.6 (0.02)
Passed bias filter:                      254  (0.014167); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.33s 00:00:00.92 Elapsed: 00:00:00.51
# Mc/sec: 3328.65
//
Query:       EEA22706.1  [L=389]
Description: hypothetical protein PMAA_093250 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
  ------ inclusion threshold ------
       0.04   14.1   0.4      0.091   12.9   0.4    1.5  1  HAS-barrel  HAS barrel domain


Domain annotation for each model (and alignments):
>> HAS-barrel  HAS barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.4   5.1e-06     0.091      35      85 ..      54     100 ..      37     109 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 5.1e-06
  HAS-barrel  35 dgeivlGmvtdirrgnselsndlalvlsleeleeangddevalatedt.gvk 85 
                 + +iv+G+v+++++     ++d + v+++  ++ +++ +e a+ t++t +v+
  EEA22706.1  54 EVGIVYGVVESVEQ-----EDDHESVRASSVRIKSEPLSEKAITTVRTgSVE 100
                 4789**********.....9999**********************9986444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (389 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       566  (0.031569); expected 358.6 (0.02)
Passed bias filter:                      415  (0.0231469); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 2729.40
//
Query:       EEA22707.1  [L=413]
Description: hypothetical protein PMAA_093260 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (413 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       672  (0.0374812); expected 358.6 (0.02)
Passed bias filter:                      464  (0.0258799); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.53u 0.29s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 2679.57
//
Query:       EEA22708.1  [L=167]
Description: nascent polypeptide-associated complex (NAC) subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.2e-25   87.9   0.7    5.2e-25   87.2   0.7    1.3  1  NAC       NAC domain


Domain annotation for each model (and alignments):
>> NAC  NAC domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.2   0.7   2.9e-29   5.2e-25       1      57 []      45     101 ..      45     101 .. 0.99

  Alignments for each domain:
  == domain 1  score: 87.2 bits;  conditional E-value: 2.9e-29
         NAC   1 ekKlrkalkklglkeipgieeVtirksdgkvlvfdnPkVqkspgsntyvvfGeaeek 57 
                 +kKl+ +lkk+++++i+ ieeV+++k+dg+v++f+nPkV+++ +snt++++G+ eek
  EEA22708.1  45 DKKLQTTLKKMNVQPIQAIEEVNMFKEDGNVIHFSNPKVHAAVPSNTFAIYGNGEEK 101
                 8******************************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (167 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1255  (0.0699983); expected 358.6 (0.02)
Passed bias filter:                      694  (0.0387082); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.24s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 1181.92
//
Query:       EEA22709.1  [L=392]
Description: short-chain dehydrogenase/reductase family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.1e-18   64.8   0.0    1.8e-13   50.4   0.0    2.4  2  adh_short        short chain dehydrogenase
      1e-09   38.3   0.1    1.8e-07   31.0   0.0    2.2  2  adh_short_C2     Enoyl-(Acyl carrier protein) reductase
    2.1e-05   24.5   0.2    4.6e-05   23.4   0.1    1.5  2  KR               KR domain
  ------ inclusion threshold ------
      0.034   14.4   0.1      0.062   13.6   0.1    1.4  1  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.4   0.0     4e-17   1.8e-13       8     128 ..      94     223 ..      92     250 .. 0.80
   2 !   12.0   0.0   2.4e-05      0.11     134     190 ..     259     313 ..     258     318 .. 0.87

  Alignments for each domain:
  == domain 1  score: 50.4 bits;  conditional E-value: 4e-17
                 TTSHHHHHHHHHHHHTT.-EEEEEESCHHHHHHHHHHHHHT..........TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGG CS
   adh_short   8 assGIGraiakelakeG.akvvvvdrseekleevakelkee..........gakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfse 95 
                 a  G+G++++ +la+ + a++++++r+e+k+e+++ ++++e          + ++ +iq+D+t+ ++++++ e+  +k  +ld+Lv NAG+   ++ + 
  EEA22709.1  94 ANTGLGKETVLQLARHNpARIYLAARNEQKAENAIRSIRQElsatgagtanEVDIQFIQLDLTSFSSIRQAAETFLQKNTRLDILVLNAGVM--AEPAI 190
                 578***********976377778**********9999988776555544444569************************************4..33333 PP

                 CSHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTT CS
   adh_short  96 lseeewervievNltgvflltravlpamlkqss 128
                 ++ +  e  + +N  g fllt+++lp++lk  s
  EEA22709.1 191 TTPQGHEIQFGTNHIGHFLLTELLLPTLLKTAS 223
                 455558888******************996654 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 2.4e-05
                 EEEGGGTSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHHH CS
   adh_short 134 vsSvagkvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdmakel 190
                 +sS   + ++  +  Y+ sKaa + ++ +la+ + +  i+ ++v+PGlv++d+ + +
  EEA22709.1 259 ISSPERLLELTTWQRYAISKAANILFATELARRYPS--ITSVSVHPGLVASDLYNGT 313
                 67777788889999******************9987..9***********9987665 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.0   0.0     4e-11   1.8e-07       4     119 ..      96     221 ..      93     257 .. 0.82
   2 !    5.3   0.1    0.0027        12     137     188 ..     270     319 ..     241     329 .. 0.88

  Alignments for each domain:
  == domain 1  score: 31.0 bits;  conditional E-value: 4e-11
                   TSHHHHHHHHHHHTT.-EEEEEESSGGH.HHHHHHHHHHTTSE.E..........EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-G CS
  adh_short_C2   4 sgIGraiAkalaeeG.aevvltdlneea.kkrveelaeelgae.v..........lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpf 87 
                    g+G++++ +la++  a++ l+ +ne++ +++++++ +el+a+ +          +++D t+ +++++++e+  +k  +lDilv nag++ +   p 
    EEA22709.1  96 TGLGKETVLQLARHNpARIYLAARNEQKaENAIRSIRQELSATgAgtanevdiqfIQLDLTSFSSIRQAAETFLQKNTRLDILVLNAGVMAE---P- 188
                   7999999999998765999999999999899999999998743322234447788************************************9...4. PP

                   GGH-HHHHHHHHHHHTHHHHHHHHHHHH.HCTS CS
  adh_short_C2  88 letsreefdraldvnlyslfllakaalp.lmke 119
                   + t+ ++ +  + +n  + fll++ +lp l+k 
    EEA22709.1 189 AITTPQGHEIQFGTNHIGHFLLTELLLPtLLKT 221
                   5577899999***************99955443 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0027
                   TTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTTHHHH CS
  adh_short_C2 137 nynaygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikgfdel 188
                     + y+++Kaa + ++  lA+ + +  i+  +v+pg+++ ++ +g + ++++
    EEA22709.1 270 TWQRYAISKAANILFATELARRYPS--ITSVSVHPGLVASDLYNGTQATNAI 319
                   5568*******************98..************9999998877665 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.4   0.1     1e-08   4.6e-05      10      98 ..      96     191 ..      93     200 .. 0.86
   2 ?   -3.3   0.0       1.7   7.4e+03     128     156 ..     253     281 ..     242     305 .. 0.62

  Alignments for each domain:
  == domain 1  score: 23.4 bits;  conditional E-value: 1e-08
                 SHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHH.HHHHHHHTT-......EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TT CS
          KR  10 GgLGlelarwlaekgarhlvllsRsaaadedska.liaelealga......evevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklle 98 
                  gLG+e++ +la++  +++ l +R++++ e++ +   +el+a+ga      +++++++D+++ ++++++ e++ +++ ++   +  Agv+++ +++
  EEA22709.1  96 TGLGKETVLQLARHNPARIYLAARNEQKAENAIRsIRQELSATGAgtanevDIQFIQLDLTSFSSIRQAAETFLQKNTRLDILVLNAGVMAEPAIT 191
                 69***********************866555554155678888878888889*************************************9987776 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 1.7
                 -SEEEEEEEHHHHH--TT-HHHHHHHHHH CS
          KR 128 ldffvlfSSiagllgsagqanYaaaNafl 156
                  d++ l+SS   ll  ++   Ya   a  
  EEA22709.1 253 PDYMQLISSPERLLELTTWQRYAISKAAN 281
                 57888888888888777777776544433 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   1.4e-05     0.062       9      63 ..      98     162 ..      96     184 .. 0.87

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 1.4e-05
                      HHHHHHHHHHCTCCT-GEEEEEESSHHHHHHHHCHH............TTTCEEEEE--TTTHHHHH CS
  Sacchrp_dh_NADP   9 vGqavaellarhfdvdaeitvadrskeklealaaka............lgvrfeaialdaenyeavL 63 
                       G+ ++  larh++   +i +a r+++k+e+++ ++            ++v++++i+ld    +++ 
       EEA22709.1  98 LGKETVLQLARHNPA--RIYLAARNEQKAENAIRSIrqelsatgagtaNEVDIQFIQLDLTSFSSIR 162
                      6999*********99..****************9999999999999999999999999998888743 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (392 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       448  (0.0249875); expected 358.6 (0.02)
Passed bias filter:                      414  (0.0230911); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 2630.41
//
Query:       EEA22710.1  [L=243]
Description: phospholipase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.5e-60  203.1   0.0    5.3e-60  202.9   0.0    1.0  1  Abhydrolase_2  Phospholipase/Carboxylesterase
    3.6e-06   26.4   0.8      0.006   15.9   0.0    3.0  3  Hydrolase_4    Serine aminopeptidase, S33
    0.00015   21.4   0.0    0.00022   20.9   0.0    1.3  1  DLH            Dienelactone hydrolase family
     0.0004   19.7   0.1       0.62    9.2   0.1    2.3  2  DUF2920        Protein of unknown function (DUF2920)
    0.00058   19.6   0.0     0.0018   18.0   0.0    1.8  1  FSH1           Serine hydrolase (FSH1)
     0.0015   18.2   0.3        1.9    8.1   0.1    3.0  3  Abhydrolase_1  alpha/beta hydrolase fold
     0.0016   18.0   0.0      0.076   12.5   0.0    2.2  2  Peptidase_S9   Prolyl oligopeptidase family
     0.0017   18.3   0.0       0.28   11.0   0.0    2.2  2  Abhydrolase_3  alpha/beta hydrolase fold
     0.0057   17.3   0.0     0.0079   16.8   0.0    1.3  1  Abhydrolase_6  Alpha/beta hydrolase family
  ------ inclusion threshold ------
      0.033   14.3   0.1      0.055   13.6   0.1    1.3  1  DUF1581        Protein of unknown function (DUF1581)


Domain annotation for each model (and alignments):
>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  202.9   0.0     3e-63   5.3e-60       4     216 ..       6     232 ..       3     233 .. 0.88

  Alignments for each domain:
  == domain 1  score: 202.9 bits;  conditional E-value: 3e-63
                    EEEE--SS---EEEEEE--TT--SHHHH...HHHH.TT--TTEEEEEE---EEE-GGGTT-EEE-SS-B--SSTTS.......-B-HHHHHHHHHH CS
  Abhydrolase_2   4 aevvspkdkaqavviflHGlGdsghawa...eaakteaalpnikfifphgpelpvtlnggmrmpaWfdlvglspek.......kedeagikksaek 89 
                    ++vv + +k++a+vi+ HGlGdsg +w    +  +  +++++++fifp++p +p t+n+gm mp W+d+ +l ++        k+de gi ks  +
     EEA22710.1   6 PFVVPAIKKHTATVIMAHGLGDSGAGWVglaQNWRRRSKFEEVSFIFPNAPMIPITVNMGMTMPGWYDIAHLGQDMdfeeaqrKQDEPGILKSRDY 101
                    7899********************77751003334468999****************************9876543333356899*********** PP

                    HHHHHHHHHHTT--GGGEEEEEETHHHHHHHHHHHT-SS--SEEEEES---TTGGGTTTTS....-GGGGG-EEEEEEETT-SSS-HHHHHHHHHH CS
  Abhydrolase_2  90 leelidaelkkgipssriiigGFSqGaalalylaltlpkklggivafsgalplsqklessa....tavtkklpilqiHgeeDpvvplalgkaakev 181
                    ++ li++e++kgi  sriiigGFSqG+a++l +++t+p+klggi+++s+ l+l++kl++       + + k+p ++ Hg+eDpvv + +g ++++ 
     EEA22710.1 102 INGLIKEEIDKGIAPSRIIIGGFSQGGAISLFTGITSPHKLGGIFGLSSYLLLATKLKEFSppggELPNAKTPFFLAHGYEDPVVKYEFGDMTQKH 197
                    *********************************************************9843122123348************************** PP

                    HHTTS-GEEEEEETT--SS--HHHHHHHHHHHHHH CS
  Abhydrolase_2 182 lkkllkkvelksyeglaHsideeemqdikeflkkl 216
                    lk +  +ve++sy+glaHs d+ee+qd++++++k 
     EEA22710.1 198 LKGMGFDVEFHSYRGLAHSADPEEIQDLEDYMEKI 232
                    ******************************99875 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0     0.041        73       2      28 ..      14      40 ..      13      43 .. 0.81
   2 !    5.3   0.1    0.0057        10      76     119 ..     117     161 ..     100     168 .. 0.83
   3 !   15.9   0.0   3.3e-06     0.006     188     233 ..     169     216 ..     166     221 .. 0.83

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.041
  Hydrolase_4  2 epkavvvlvHGlaehsgryaelaeaLa 28
                 ++ a+v+++HGl+++      la+++ 
   EEA22710.1 14 KHTATVIMAHGLGDSGAGWVGLAQNWR 40
                 6889**********9888777777765 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0057
  Hydrolase_4  76 lplfllGhSmGGliallyllrypdkvaglilsaPalkikaklk.a 119
                  +++++ G S GG+i+l  + + p+k+ g+   ++ l +++klk +
   EEA22710.1 117 SRIIIGGFSQGGAISLFTGITSPHKLGGIFGLSSYLLLATKLKeF 161
                  478999*******************99999999988888776544 PP

  == domain 3  score: 15.9 bits;  conditional E-value: 3.3e-06
  Hydrolase_4 188 akitlPllllhGeaDkvvdpeas...relyerlgskdktlklypglyHe 233
                  +++++P++l hG +D+vv++e     ++ ++ +g  d++++ y gl H+
   EEA22710.1 169 PNAKTPFFLAHGYEDPVVKYEFGdmtQKHLKGMGF-DVEFHSYRGLAHS 216
                  6789*****************99444555555555.************7 PP

>> DLH  Dienelactone hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.0   1.2e-07   0.00022      96     188 ..     115     216 ..      82     231 .. 0.84

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 1.2e-07
         DLH  96 stkkvgvvGfCmGGalalllaaev.pevdaavafYG...........lspekeleeaakikapilalfgeeDefipadevekleealkaanvdlelkvY 182
                  ++++ + Gf  GGa++l        ++ +     G           ++++++  e +++k+p +  +g eD++++ +  + +++ lk  + d+e+++Y
  EEA22710.1 115 APSRIIIGGFSQGGAISLFTGITSpHKLGGIF---GlssylllatklKEFSPPGGELPNAKTPFFLAHGYEDPVVKYEFGDMTQKHLKGMGFDVEFHSY 210
                 57899999999999999876666624555544...44457799999889999999***********************9999999************** PP

         DLH 183 pgagHa 188
                  g +H+
  EEA22710.1 211 RGLAHS 216
                 *****8 PP

>> DUF2920  Protein of unknown function (DUF2920)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.2   0.1   0.00035      0.62     155     214 ..      93     151 ..      79     158 .. 0.81
   2 !    8.2   0.0   0.00068       1.2     284     323 ..     171     210 ..     167     230 .. 0.81

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00035
     DUF2920 155 fGimaAlDiinal.kdlvkrfpkeadlpviliGgsyGGYlalLiaKiaPwyvdgvlDnssv 214
                  Gi++  D+in l k+ + + ++     +i++G s GG ++l      P  + g++  ss+
  EEA22710.1  93 PGILKSRDYINGLiKEEIDK-GIAP-SRIIIGGFSQGGAISLFTGITSPHKLGGIFGLSSY 151
                 69*********861445554.4443.68999999*********9999********999988 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.00068
     DUF2920 284 kntiyvsyHsekDklapaeeKiqlakilkklgfdveleli 323
                  +t ++  H  +D+++  e+  ++ k lk +gfdve+++ 
  EEA22710.1 171 AKTPFFLAHGYEDPVVKYEFGDMTQKHLKGMGFDVEFHSY 210
                 4588999******************************987 PP

>> FSH1  Serine hydrolase (FSH1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.0   0.0   9.9e-07    0.0018       4     118 ..      16     133 ..      12     209 .. 0.69

  Alignments for each domain:
  == domain 1  score: 18.0 bits;  conditional E-value: 9.9e-07
        FSH1   4 kkkiLcLhGytqsgeiFraktsalrkllkklnvelvyldaplelaekadlpkseseeeekseeeeesraWfrkkdekneyegleesldavkdyike... 99 
                 + ++++ hG + sg  +    +++r+  k ++v++++++ap+    ++++  +     + +  +  +   f++ ++k++  g+ +s d+++  ike   
  EEA22710.1  16 TATVIMAHGLGDSGAGWVGLAQNWRRRSKFEEVSFIFPNAPMIP-ITVNMGMT--MPGWYDIAHLGQDMDFEEAQRKQDEPGILKSRDYINGLIKEeid 111
                 67899*********************99999**********988.44444433..33445666666666677777799******************555 PP

        FSH1 100 ..ngpfdGii.GFSqGaalaal 118
                     p   ii GFSqG+a++  
  EEA22710.1 112 kgIAPSRIIIgGFSQGGAISLF 133
                 442345555538*****99754 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.0     0.016        29       2      30 ..      18      45 ..      17      56 .. 0.82
   2 !    8.1   0.1    0.0011       1.9      74     106 ..     118     150 ..     106     165 .. 0.85
   3 ?    2.9   0.0      0.04        72     207     239 ..     168     200 ..     151     217 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.016
                   EEEEE-STTTCGGGGTTGHHHHHHHHT.TS CS
  Abhydrolase_1  2 vlvilhGlpgssdvwaerglapaLakd.gf 30
                   ++++ hGl++s+  w +  la++  ++ +f
     EEA22710.1 18 TVIMAHGLGDSGAGWVG--LAQNWRRRsKF 45
                   599**************..99988777655 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0011
                    SEEEEEETHHHHHHHHHHHHHGGGEEEEEEESE CS
  Abhydrolase_1  74 kltlvGhSmGGmialayaaeyperVkalvllga 106
                    ++++ G+S+GG+i+l      p++  ++  l++
     EEA22710.1 118 RIIIGGFSQGGAISLFTGITSPHKLGGIFGLSS 150
                    68899******************9999988887 PP

  == domain 3  score: 2.9 bits;  conditional E-value: 0.04
                    THHHHSEEEEEEETTCSSSCHHHHHHHHHCHTS CS
  Abhydrolase_1 207 lknvlaptlvisgtsDplvppkaledlaqllpk 239
                    l n++ p ++ +g +Dp+v+++ ++  +++l++
     EEA22710.1 168 LPNAKTPFFLAHGYEDPVVKYEFGDMTQKHLKG 200
                    668899**************9887777777665 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.2   0.0     0.029        52      60      79 ..     113     132 ..      83     141 .. 0.81
   2 !   12.5   0.0   4.3e-05     0.076     139     201 ..     170     225 ..     154     234 .. 0.82

  Alignments for each domain:
  == domain 1  score: 3.2 bits;  conditional E-value: 0.029
                   S--GGGEEEEEETHHHHHHH CS
  Peptidase_S9  60 yvdserlaitGgSyGGyltg 79 
                    + ++r++i G S GG  ++
    EEA22710.1 113 GIAPSRIIIGGFSQGGAISL 132
                   4679************8765 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 4.3e-05
                   G-----EEEEEEETT-SSS-THHHHHHHHHHH--S-SEEEEEETTS-SSTTSSHHHHHHHHHH CS
  Peptidase_S9 139 nvkaypplLlihGlaDdrvppaealklvaaLqkkgknvlllifpdegHgvgkprakveelarl 201
                   n  a++p++l hG +D  v ++ + +  + L+  g +v+++ + +  H++       ee+++l
    EEA22710.1 170 N--AKTPFFLAHGYEDPVVKYEFGDMTQKHLKGMGFDVEFHSYRGLAHSAD-----PEEIQDL 225
                   4..89*******************************************443.....3444444 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.0   0.00016      0.28      55      88 ..     101     134 ..      95     156 .. 0.85
   2 !    5.2   0.0    0.0091        16     170     208 ..     176     216 ..     155     218 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00016
                    HHHHHHHTHHHHTETTCEEEEEEETHHHHHHHHH CS
  Abhydrolase_3  55 alrwlaeqawelgadpsrivlaGdSaGGnlaaav 88 
                     ++ l +++ ++g+ psri+++G S GG +++ +
     EEA22710.1 101 YINGLIKEEIDKGIAPSRIIIGGFSQGGAISLFT 134
                    566778887799******************9876 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0091
                    EEEEETT-TTH..HHHHHHHHHHHHTT--EEEEEETTEETT CS
  Abhydrolase_3 170 lvvvaefDplr..degeayaerlraagvevelieyegmvHg 208
                    +++ + +Dp    + g ++ ++l+ +g +ve++ y+g+ H+
     EEA22710.1 176 FLAHGYEDPVVkyEFGDMTQKHLKGMGFDVEFHSYRGLAHS 216
                    55555556554113578899********************6 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.0   4.4e-06    0.0079       1      97 [.      19     164 ..      19     235 .. 0.56

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 4.4e-06
                    EEEE--GC.....GCHHHHHHHHCCT.......CEEEEE--T........TSTS-GGCS--HHHC...HHHHHHHCCTT................. CS
  Abhydrolase_6   1 vlllHGagssassWlvapLaallaag.......vhvlapDlp........GhGrsdpppldledl...adlaalldelaa................ 62 
                    v+++HG+g s+ +W    La   +++       +  + p +p        G+  + p ++d + l    d++++ ++ ++                
     EEA22710.1  19 VIMAHGLGDSGAGWV--GLAQNWRRRskfeevsF--IFPNAPmipitvnmGM--TMPGWYDIAHLgqdMDFEEAQRKQDEpgilksrdyinglike 108
                    7899**********6..44444444455346442..5566667777774444..444444443322221112222222223333333444444445 PP

                    .......TTSEEEEEETCHHHHHHHHHHCC.............EE.EEES-........ CS
  Abhydrolase_6  63 ......gggpvvlvGHSlGGalalaaapla...........lvvg.vlldp......pp 97 
                           + ++++ G S+GGa++l+                 +++ +ll++      pp
     EEA22710.1 109 eidkgiAPSRIIIGGFSQGGAISLF---TGitsphklggifGLSSyLLLATklkefsPP 164
                    55578778888*************9...3333366577544223367777766655433 PP

>> DUF1581  Protein of unknown function (DUF1581)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   3.1e-05     0.055      18      71 ..      20      73 ..      13      81 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 3.1e-05
     DUF1581 18 ilkesvaasaaPWvalrssrtkkgvvrnlr..itGePeiPdkvdlveseeLlGWss 71
                i+ + + +s a Wv+l  +++ +++++++      +P iP +v++  +  + GW++
  EEA22710.1 20 IMAHGLGDSGAGWVGLAQNWRRRSKFEEVSfiFPNAPMIPITVNM--GMTMPGWYD 73
                556667788999***************987224799********9..778899987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (243 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       336  (0.0187406); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.49u 0.33s 00:00:00.82 Elapsed: 00:00:00.47
# Mc/sec: 1570.70
//
Query:       EEA22711.1  [L=180]
Description: phospholipase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.4e-41  142.7   0.0    1.6e-41  142.5   0.0    1.1  1  Abhydrolase_2  Phospholipase/Carboxylesterase
    1.6e-05   24.3   0.3     0.0035   16.6   0.0    2.1  2  Hydrolase_4    Serine aminopeptidase, S33
    7.6e-05   22.4   0.0    9.5e-05   22.0   0.0    1.2  1  DLH            Dienelactone hydrolase family
    0.00016   21.0   0.1       0.31   10.2   0.0    2.1  2  DUF2920        Protein of unknown function (DUF2920)
     0.0007   19.5   0.0       0.19   11.6   0.0    2.1  2  Abhydrolase_3  alpha/beta hydrolase fold
    0.00072   19.1   0.0      0.039   13.4   0.0    2.1  2  Peptidase_S9   Prolyl oligopeptidase family
  ------ inclusion threshold ------
      0.029   14.0   0.1        1.1    8.9   0.1    2.1  2  Abhydrolase_1  alpha/beta hydrolase fold


Domain annotation for each model (and alignments):
>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  142.5   0.0   6.4e-45   1.6e-41      59     216 ..       1     169 [.       1     170 [. 0.90

  Alignments for each domain:
  == domain 1  score: 142.5 bits;  conditional E-value: 6.4e-45
                    TT-EEE-SS-B--SSTTS.......-B-HHHHHHHHHHHHHHHHHHHHTT--GGGEEEEEETHHHHHHHHHHHT-SS--SEEEEES---TTGGGTT CS
  Abhydrolase_2  59 ggmrmpaWfdlvglspek.......kedeagikksaekleelidaelkkgipssriiigGFSqGaalalylaltlpkklggivafsgalplsqkle 147
                    +gm mp W+d+ +l ++        k+de gi ks  +++ li++e++kgi  sriiigGFSqG+a++l +++t+p+klggi+++s+ l+l++kl+
     EEA22711.1   1 MGMTMPGWYDIAHLGQDMdfeeaqrKQDEPGILKSRDYINGLIKEEIDKGIAPSRIIIGGFSQGGAISLFTGITSPHKLGGIFGLSSYLLLATKLK 96 
                    79*********9876543333356899********************************************************************9 PP

                    TTS....-GGGGG-EEEEEEETT-SSS-HHHHHHHHHHHHTTS-GEEEEEETT--SS--HHHHHHHHHHHHHH CS
  Abhydrolase_2 148 ssa....tavtkklpilqiHgeeDpvvplalgkaakevlkkllkkvelksyeglaHsideeemqdikeflkkl 216
                    +       + + k+p ++ Hg+eDpvv + +g ++++ lk +  +ve++sy+glaHs d+ee+qd++++++k 
     EEA22711.1  97 EFSppggELPNAKTPFFLAHGYEDPVVKYEFGDMTQKHLKGMGFDVEFHSYRGLAHSADPEEIQDLEDYMEKI 169
                    843122123348********************************************************99875 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.1   0.1    0.0023         6      76     119 ..      54      98 ..      37     105 .. 0.83
   2 !   16.6   0.0   1.4e-06    0.0035     188     233 ..     106     153 ..     103     158 .. 0.83

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0023
  Hydrolase_4  76 lplfllGhSmGGliallyllrypdkvaglilsaPalkikaklk.a 119
                  +++++ G S GG+i+l  + + p+k+ g+   ++ l +++klk +
   EEA22711.1  54 SRIIIGGFSQGGAISLFTGITSPHKLGGIFGLSSYLLLATKLKeF 98 
                  478999********************9999999988888776554 PP

  == domain 2  score: 16.6 bits;  conditional E-value: 1.4e-06
  Hydrolase_4 188 akitlPllllhGeaDkvvdpeas...relyerlgskdktlklypglyHe 233
                  +++++P++l hG +D+vv++e     ++ ++ +g  d++++ y gl H+
   EEA22711.1 106 PNAKTPFFLAHGYEDPVVKYEFGdmtQKHLKGMGF-DVEFHSYRGLAHS 153
                  6789*****************99444555555555.************7 PP

>> DLH  Dienelactone hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.0   0.0   3.7e-08   9.5e-05      96     188 ..      52     153 ..      19     168 .. 0.84

  Alignments for each domain:
  == domain 1  score: 22.0 bits;  conditional E-value: 3.7e-08
         DLH  96 stkkvgvvGfCmGGalalllaaev.pevdaavafYG...........lspekeleeaakikapilalfgeeDefipadevekleealkaanvdlelkvY 182
                  ++++ + Gf  GGa++l        ++ +     G           ++++++  e +++k+p +  +g eD++++ +  + +++ lk  + d+e+++Y
  EEA22711.1  52 APSRIIIGGFSQGGAISLFTGITSpHKLGGIF---GlssylllatklKEFSPPGGELPNAKTPFFLAHGYEDPVVKYEFGDMTQKHLKGMGFDVEFHSY 147
                 57899999999999999876666624555544...44458899999889999999***********************9999999************** PP

         DLH 183 pgagHa 188
                  g +H+
  EEA22711.1 148 RGLAHS 153
                 *****8 PP

>> DUF2920  Protein of unknown function (DUF2920)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.2   0.0   0.00012      0.31     155     215 ..      30      89 ..      11      95 .. 0.81
   2 !    9.0   0.0   0.00027      0.69     284     334 ..     108     160 ..     104     168 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00012
     DUF2920 155 fGimaAlDiinal.kdlvkrfpkeadlpviliGgsyGGYlalLiaKiaPwyvdgvlDnssva 215
                  Gi++  D+in l k+ + + ++     +i++G s GG ++l      P  + g++  ss+ 
  EEA22711.1  30 PGILKSRDYINGLiKEEIDK-GIAP-SRIIIGGFSQGGAISLFTGITSPHKLGGIFGLSSYL 89 
                 69*********861445554.4443.68999999**********999*********999985 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00027
     DUF2920 284 kntiyvsyHsekDklapaeeKiqlakilkklgfdveleli..desdiDGkfik 334
                  +t ++  H  +D+++  e+  ++ k lk +gfdve+++    + + D + i+
  EEA22711.1 108 AKTPFFLAHGYEDPVVKYEFGDMTQKHLKGMGFDVEFHSYrgLAHSADPEEIQ 160
                 4588999******************************9874334555555555 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.6   0.0   7.2e-05      0.19      55      88 ..      38      71 ..      31      83 .. 0.85
   2 !    5.9   0.0    0.0039        10     169     208 ..     112     153 ..      93     155 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 7.2e-05
                   HHHHHHHTHHHHTETTCEEEEEEETHHHHHHHHH CS
  Abhydrolase_3 55 alrwlaeqawelgadpsrivlaGdSaGGnlaaav 88
                    ++ l +++ ++g+ psri+++G S GG +++ +
     EEA22711.1 38 YINGLIKEEIDKGIAPSRIIIGGFSQGGAISLFT 71
                   567788887799******************9876 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0039
                    EEEEEETT-TTH..HHHHHHHHHHHHTT--EEEEEETTEETT CS
  Abhydrolase_3 169 tlvvvaefDplr..degeayaerlraagvevelieyegmvHg 208
                     +++ + +Dp    + g ++ ++l+ +g +ve++ y+g+ H+
     EEA22711.1 112 FFLAHGYEDPVVkyEFGDMTQKHLKGMGFDVEFHSYRGLAHS 153
                    555555566654114578999********************6 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.012        32      60      79 ..      50      69 ..      19      78 .. 0.80
   2 !   13.4   0.0   1.5e-05     0.039     139     203 ..     107     164 ..      89     172 .. 0.82

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.012
                  S--GGGEEEEEETHHHHHHH CS
  Peptidase_S9 60 yvdserlaitGgSyGGyltg 79
                   + ++r++i G S GG  ++
    EEA22711.1 50 GIAPSRIIIGGFSQGGAISL 69
                  4779************8765 PP

  == domain 2  score: 13.4 bits;  conditional E-value: 1.5e-05
                   G-----EEEEEEETT-SSS-THHHHHHHHHHH--S-SEEEEEETTS-SSTTSSHHHHHHHHHHHH CS
  Peptidase_S9 139 nvkaypplLlihGlaDdrvppaealklvaaLqkkgknvlllifpdegHgvgkprakveelarlla 203
                   n  a++p++l hG +D  v ++ + +  + L+  g +v+++ + +  H++       ee+++l +
    EEA22711.1 107 N--AKTPFFLAHGYEDPVVKYEFGDMTQKHLKGMGFDVEFHSYRGLAHSA-----DPEEIQDLED 164
                   4..89*******************************************44.....3444444444 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   0.1   0.00042       1.1      74     106 ..      55      87 ..      45     105 .. 0.84
   2 ?    3.5   0.0     0.018        46     207     239 ..     105     137 ..      90     154 .. 0.78

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00042
                    SEEEEEETHHHHHHHHHHHHHGGGEEEEEEESE CS
  Abhydrolase_1  74 kltlvGhSmGGmialayaaeyperVkalvllga 106
                    ++++ G+S+GG+i+l      p++  ++  l++
     EEA22711.1  55 RIIIGGFSQGGAISLFTGITSPHKLGGIFGLSS 87 
                    68899*******************999998888 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.018
                    THHHHSEEEEEEETTCSSSCHHHHHHHHHCHTS CS
  Abhydrolase_1 207 lknvlaptlvisgtsDplvppkaledlaqllpk 239
                    l n++ p ++ +g +Dp+v+++ ++  +++l++
     EEA22711.1 105 LPNAKTPFFLAHGYEDPVVKYEFGDMTQKHLKG 137
                    668899**************9888777777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (180 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       301  (0.0167884); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1236.69
//
Query:       EEA22712.1  [L=225]
Description: phospholipase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.1e-54  184.1   0.0    3.6e-54  183.9   0.0    1.1  1  Abhydrolase_2  Phospholipase/Carboxylesterase
    0.00027   20.3   0.2       0.83    8.9   0.0    3.0  3  Hydrolase_4    Serine aminopeptidase, S33
    0.00039   19.7   0.0       0.54    9.4   0.0    2.3  2  DUF2920        Protein of unknown function (DUF2920)
    0.00049   19.8   0.0     0.0014   18.3   0.0    1.8  1  FSH1           Serine hydrolase (FSH1)
    0.00088   19.0   0.3        1.7    8.2   0.1    3.0  3  Abhydrolase_1  alpha/beta hydrolase fold
      0.007   17.0   0.0     0.0091   16.6   0.0    1.2  1  Abhydrolase_6  Alpha/beta hydrolase family
  ------ inclusion threshold ------
      0.015   14.8   0.0      0.022   14.3   0.0    1.3  1  DLH            Dienelactone hydrolase family
      0.029   14.5   0.1      0.048   13.8   0.1    1.3  1  DUF1581        Protein of unknown function (DUF1581)
      0.079   12.8   0.0       0.22   11.4   0.0    1.7  2  Abhydrolase_3  alpha/beta hydrolase fold
       0.14   11.6   0.0        7.9    5.9   0.0    2.3  2  Peptidase_S9   Prolyl oligopeptidase family


Domain annotation for each model (and alignments):
>> Abhydrolase_2  Phospholipase/Carboxylesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  183.9   0.0     2e-57   3.6e-54       4     204 ..       6     220 ..       3     225 .] 0.86

  Alignments for each domain:
  == domain 1  score: 183.9 bits;  conditional E-value: 2e-57
                    EEEE--SS---EEEEEE--TT--SHHHH...HHHH.TT--TTEEEEEE---EEE-GGGTT-EEE-SS-B--SSTTS.......-B-HHHHHHHHHH CS
  Abhydrolase_2   4 aevvspkdkaqavviflHGlGdsghawa...eaakteaalpnikfifphgpelpvtlnggmrmpaWfdlvglspek.......kedeagikksaek 89 
                    ++vv + +k++a+vi+ HGlGdsg +w    +  +  +++++++fifp++p +p t+n+gm mp W+d+ +l ++        k+de gi ks  +
     EEA22712.1   6 PFVVPAIKKHTATVIMAHGLGDSGAGWVglaQNWRRRSKFEEVSFIFPNAPMIPITVNMGMTMPGWYDIAHLGQDMdfeeaqrKQDEPGILKSRDY 101
                    7899********************77751003334468999****************************9876543333356899*********** PP

                    HHHHHHHHHHTT--GGGEEEEEETHHHHHHHHHHHT-SS--SEEEEES---TTGGGTTTTS....-GGGGG-EEEEEEETT-SSS-HHHHHHHHHH CS
  Abhydrolase_2  90 leelidaelkkgipssriiigGFSqGaalalylaltlpkklggivafsgalplsqklessa....tavtkklpilqiHgeeDpvvplalgkaakev 181
                    ++ li++e++kgi  sriiigGFSqG+a++l +++t+p+klggi+++s+ l+l++kl++       + + k+p ++ Hg+eDpvv + +g ++++ 
     EEA22712.1 102 INGLIKEEIDKGIAPSRIIIGGFSQGGAISLFTGITSPHKLGGIFGLSSYLLLATKLKEFSppggELPNAKTPFFLAHGYEDPVVKYEFGDMTQKH 197
                    *********************************************************9843122123348************************** PP

                    HHTTS-GEEEEEETT--SS--HH CS
  Abhydrolase_2 182 lkkllkkvelksyeglaHsidee 204
                    lk +  +ve++sy+ ++ s +++
     EEA22712.1 198 LKGMGFDVEFHSYRCVQDSGSGV 220
                    *************9877776665 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   0.0     0.037        66       2      28 ..      14      40 ..      13      43 .. 0.82
   2 !    5.4   0.1    0.0053       9.6      76     118 ..     117     159 ..     100     167 .. 0.83
   3 !    8.9   0.0   0.00046      0.83     188     227 ..     169     210 ..     165     212 .. 0.73

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.037
  Hydrolase_4  2 epkavvvlvHGlaehsgryaelaeaLa 28
                 ++ a+v+++HGl+++      la+++ 
   EEA22712.1 14 KHTATVIMAHGLGDSGAGWVGLAQNWR 40
                 6889**********9888777777765 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.0053
  Hydrolase_4  76 lplfllGhSmGGliallyllrypdkvaglilsaPalkikaklk 118
                  +++++ G S GG+i+l  + + p+k+ g+   ++ l +++klk
   EEA22712.1 117 SRIIIGGFSQGGAISLFTGITSPHKLGGIFGLSSYLLLATKLK 159
                  478999*******************999999999888887765 PP

  == domain 3  score: 8.9 bits;  conditional E-value: 0.00046
  Hydrolase_4 188 akitlPllllhGeaDkvvdpeasrelyerlgsk..dktlkly 227
                  +++++P++l hG +D+vv++e    + ++l+    d++++ y
   EEA22712.1 169 PNAKTPFFLAHGYEDPVVKYEFGDMTQKHLKGMgfDVEFHSY 210
                  6789***************99885544444433336666666 PP

>> DUF2920  Protein of unknown function (DUF2920)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.4   0.0    0.0003      0.54     155     214 ..      93     151 ..      80     158 .. 0.81
   2 !    8.1   0.0   0.00074       1.3     284     323 ..     171     210 ..     167     225 .] 0.85

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.0003
     DUF2920 155 fGimaAlDiinal.kdlvkrfpkeadlpviliGgsyGGYlalLiaKiaPwyvdgvlDnssv 214
                  Gi++  D+in l k+ + + ++     +i++G s GG ++l      P  + g++  ss+
  EEA22712.1  93 PGILKSRDYINGLiKEEIDK-GIAP-SRIIIGGFSQGGAISLFTGITSPHKLGGIFGLSSY 151
                 59*********861445554.4443.68999999*********9999********999998 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.00074
     DUF2920 284 kntiyvsyHsekDklapaeeKiqlakilkklgfdveleli 323
                  +t ++  H  +D+++  e+  ++ k lk +gfdve+++ 
  EEA22712.1 171 AKTPFFLAHGYEDPVVKYEFGDMTQKHLKGMGFDVEFHSY 210
                 4588999*****************************9986 PP

>> FSH1  Serine hydrolase (FSH1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0     8e-07    0.0014       4     118 ..      16     133 ..      12     208 .. 0.69

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 8e-07
        FSH1   4 kkkiLcLhGytqsgeiFraktsalrkllkklnvelvyldaplelaekadlpkseseeeekseeeeesraWfrkkdekneyegleesldavkdyike... 99 
                 + ++++ hG + sg  +    +++r+  k ++v++++++ap+    ++++  +     + +  +  +   f++ ++k++  g+ +s d+++  ike   
  EEA22712.1  16 TATVIMAHGLGDSGAGWVGLAQNWRRRSKFEEVSFIFPNAPMIP-ITVNMGMT--MPGWYDIAHLGQDMDFEEAQRKQDEPGILKSRDYINGLIKEeid 111
                 67899*********************99999**********988.44444433..33445666666666677777799******************555 PP

        FSH1 100 ..ngpfdGii.GFSqGaalaal 118
                     p   ii GFSqG+a++  
  EEA22712.1 112 kgIAPSRIIIgGFSQGGAISLF 133
                 442345555538*****99754 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0     0.015        26       2      30 ..      18      45 ..      17      56 .. 0.82
   2 !    8.2   0.1   0.00094       1.7      74     106 ..     118     150 ..     106     165 .. 0.85
   3 ?    3.5   0.0     0.026        46     207     239 ..     168     200 ..     153     222 .. 0.75

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.015
                   EEEEE-STTTCGGGGTTGHHHHHHHHT.TS CS
  Abhydrolase_1  2 vlvilhGlpgssdvwaerglapaLakd.gf 30
                   ++++ hGl++s+  w +  la++  ++ +f
     EEA22712.1 18 TVIMAHGLGDSGAGWVG--LAQNWRRRsKF 45
                   599**************..99988777655 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.00094
                    SEEEEEETHHHHHHHHHHHHHGGGEEEEEEESE CS
  Abhydrolase_1  74 kltlvGhSmGGmialayaaeyperVkalvllga 106
                    ++++ G+S+GG+i+l      p++  ++  l++
     EEA22712.1 118 RIIIGGFSQGGAISLFTGITSPHKLGGIFGLSS 150
                    68899******************9999988887 PP

  == domain 3  score: 3.5 bits;  conditional E-value: 0.026
                    THHHHSEEEEEEETTCSSSCHHHHHHHHHCHTS CS
  Abhydrolase_1 207 lknvlaptlvisgtsDplvppkaledlaqllpk 239
                    l n++ p ++ +g +Dp+v+++ ++  +++l++
     EEA22712.1 168 LPNAKTPFFLAHGYEDPVVKYEFGDMTQKHLKG 200
                    668899***************988888888666 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   5.1e-06    0.0091       1      96 [.      19     163 ..      19     211 .. 0.56

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 5.1e-06
                    EEEE--GC.....GCHHHHHHHHCCT.......CEEEEE--T........TSTS-GGCS--HHHC...HHHHHHHCCTT................. CS
  Abhydrolase_6   1 vlllHGagssassWlvapLaallaag.......vhvlapDlp........GhGrsdpppldledl...adlaalldelaa................ 62 
                    v+++HG+g s+ +W    La   +++       +  + p +p        G+  + p ++d + l    d++++ ++ ++                
     EEA22712.1  19 VIMAHGLGDSGAGWV--GLAQNWRRRskfeevsF--IFPNAPmipitvnmGM--TMPGWYDIAHLgqdMDFEEAQRKQDEpgilksrdyinglike 108
                    7899**********6..44444444455346442..5566667777774444..444444443322221112222222223333334444444445 PP

                    .......TTSEEEEEETCHHHHHHHHHHCC.............EE.EEES-....... CS
  Abhydrolase_6  63 ......gggpvvlvGHSlGGalalaaapla...........lvvg.vlldp......p 96 
                           + ++++ G S+GGa++l+                 +++ +ll++      p
     EEA22712.1 109 eidkgiAPSRIIIGGFSQGGAISLF---TGitsphklggifGLSSyLLLATklkefsP 163
                    55578778888*************9...333335556754422336666665555543 PP

>> DLH  Dienelactone hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   1.2e-05     0.022      96     183 ..     115     211 ..      81     216 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 1.2e-05
         DLH  96 stkkvgvvGfCmGGalalllaaev.pevdaavafYG...........lspekeleeaakikapilalfgeeDefipadevekleealkaanvdlelkvY 182
                  ++++ + Gf  GGa++l        ++ +     G           ++++++  e +++k+p +  +g eD++++ +  + +++ lk  + d+e+++Y
  EEA22712.1 115 APSRIIIGGFSQGGAISLFTGITSpHKLGGIF---GlssylllatklKEFSPPGGELPNAKTPFFLAHGYEDPVVKYEFGDMTQKHLKGMGFDVEFHSY 210
                 57899999999999999876666624555544...44457799999889999999***********************99999999************* PP

         DLH 183 p 183
                  
  EEA22712.1 211 R 211
                 6 PP

>> DUF1581  Protein of unknown function (DUF1581)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.1   2.7e-05     0.048      18      71 ..      20      73 ..      13      81 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 2.7e-05
     DUF1581 18 ilkesvaasaaPWvalrssrtkkgvvrnlr..itGePeiPdkvdlveseeLlGWss 71
                i+ + + +s a Wv+l  +++ +++++++      +P iP +v++  +  + GW++
  EEA22712.1 20 IMAHGLGDSGAGWVGLAQNWRRRSKFEEVSfiFPNAPMIPITVNM--GMTMPGWYD 73
                556667788999***************987224799********9..778899987 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   0.00012      0.22      54      89 ..     100     135 ..      93     162 .. 0.86
   2 ?   -1.5   0.0         1   1.9e+03     170     203 ..     176     211 ..     149     213 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00012
                    HHHHHHHHTHHHHTETTCEEEEEEETHHHHHHHHHH CS
  Abhydrolase_3  54 aalrwlaeqawelgadpsrivlaGdSaGGnlaaava 89 
                    + ++ l +++ ++g+ psri+++G S GG +++ + 
     EEA22712.1 100 DYINGLIKEEIDKGIAPSRIIIGGFSQGGAISLFTG 135
                    5567788887799******************98765 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1
                    EEEEETT-TTH..HHHHHHHHHHHHTT--EEEEEET CS
  Abhydrolase_3 170 lvvvaefDplr..degeayaerlraagvevelieye 203
                    +++ + +Dp    + g ++ ++l+ +g +ve++ y+
     EEA22712.1 176 FLAHGYEDPVVkyEFGDMTQKHLKGMGFDVEFHSYR 211
                    555555555541135778899999999999999885 PP

>> Peptidase_S9  Prolyl oligopeptidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.0     0.026        47      60      79 ..     113     132 ..      83     141 .. 0.81
   2 ?    5.9   0.0    0.0044       7.9     139     180 ..     170     209 ..     153     215 .. 0.82

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.026
                   S--GGGEEEEEETHHHHHHH CS
  Peptidase_S9  60 yvdserlaitGgSyGGyltg 79 
                    + ++r++i G S GG  ++
    EEA22712.1 113 GIAPSRIIIGGFSQGGAISL 132
                   4679************8765 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0044
                   G-----EEEEEEETT-SSS-THHHHHHHHHHH--S-SEEEEE CS
  Peptidase_S9 139 nvkaypplLlihGlaDdrvppaealklvaaLqkkgknvllli 180
                   n  a++p++l hG +D  v ++ + +  + L+  g +v+++ 
    EEA22712.1 170 N--AKTPFFLAHGYEDPVVKYEFGDMTQKHLKGMGFDVEFHS 209
                   4..89****************988888888887777777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (225 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       251  (0.0139997); expected 358.6 (0.02)
Passed bias filter:                      236  (0.013163); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.49u 0.29s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 1459.59
//
Query:       EEA22713.1  [L=233]
Description: GPI anchored protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
        8.3    6.0  10.7         11    5.6  10.7    1.1  1  PAP1      Transcription factor PAP1


Domain annotation for each model (and alignments):
>> PAP1  Transcription factor PAP1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6  10.7   0.00063        11      94     161 ..     144     210 ..     116     218 .. 0.59

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.00063
        PAP1  94 nnnys.nsaanegltrgstassaesqsstysansgtsts....sdSPsssseshqgqlSScgTSPEPstqSPa 161
                  +++s +s an+ +  +s+ s a+   +t + +++  +     s+SPssss      +SS  TS  Pst+  a
  EEA22713.1 144 LTKNSpTSCANASSISASALSGAD-GARTANLSNADGSArsgsSASPSSSS-----GSSSATTSASPSTHTGA 210
                 444553444444444444434333.33444443333222212255555554.....35799999999998755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (233 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       626  (0.0349155); expected 358.6 (0.02)
Passed bias filter:                      294  (0.016398); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 1539.81
//
Query:       EEA22714.1  [L=115]
Description: Ctr copper transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.3e-17   64.0   0.2    2.4e-17   63.9   0.2    1.0  1  Ctr            Ctr copper transporter family
  ------ inclusion threshold ------
       0.04   14.3   0.2      0.056   13.8   0.2    1.2  1  Papilloma_E5A  Papillomavirus E5A protein
      0.044   13.5   0.4       0.05   13.4   0.4    1.1  1  PAP2           PAP2 superfamily


Domain annotation for each model (and alignments):
>> Ctr  Ctr copper transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.9   0.2   4.1e-21   2.4e-17      83     147 ..      30     104 ..       2     105 .. 0.78

  Alignments for each domain:
  == domain 1  score: 63.9 bits;  conditional E-value: 4.1e-21
         Ctr  83 a............kstsslskseakksvrttpeqqlirallyvvqvllaYilMLlvMtyNvglflavilGagvGefl 147
                 +            + + +++ +++++++r++++  l ra+l +v ++++Y+lML+vMt+Nvg+f++v++G+++Ge++
  EEA22714.1  30 TktgtltcqgvdeTVRVVRQVTTETQPWRFSVD--LPRAILAFVVTGVSYLLMLAVMTMNVGYFMSVLAGTFIGELA 104
                 022344555565688888999999999999999..***************************************986 PP

>> Papilloma_E5A  Papillomavirus E5A protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.2   9.4e-06     0.056      47      88 ..      70     111 ..      65     114 .. 0.93

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 9.4e-06
  Papilloma_E5A  47 lvltlllylllwlllttalqfylltlslcflpafsvhlyilq 88 
                    +v+t + yll+  ++t ++ +++  l+  f+  ++v  yi++
     EEA22714.1  70 FVVTGVSYLLMLAVMTMNVGYFMSVLAGTFIGELAVGRYIVH 111
                    589999**********************************98 PP

>> PAP2  PAP2 superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.4   8.4e-06      0.05      83     125 ..      58     106 ..      31     114 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 8.4e-06
        PAP2  83 g......lvllalillllavlvalsRlylgvHflsDvlaGlliGialaa 125
                 +      + +la++++ ++ l +l+ +  +v +++ vlaG++iG + + 
  EEA22714.1  58 RfsvdlpRAILAFVVTGVSYLLMLAVMTMNVGYFMSVLAGTFIGELAVG 106
                 1334567889**********************************87654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (115 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       781  (0.0435607); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.42
# Mc/sec: 817.41
//
Query:       EEA22715.1  [L=684]
Description: metalloreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.7e-21   75.7   0.0    9.3e-21   74.0   0.0    1.9  2  FAD_binding_8  FAD-binding domain
    1.8e-19   70.4   0.1    3.4e-19   69.5   0.1    1.5  1  NAD_binding_6  Ferric reductase NAD binding domain
    2.6e-19   69.6  13.2    6.9e-19   68.2  13.2    1.8  1  Ferric_reduct  Ferric reductase like transmembrane component
  ------ inclusion threshold ------
      0.031   14.9   0.1         12    6.6   0.0    3.1  3  NAD_binding_1  Oxidoreductase NAD-binding domain
       0.06   13.7   0.0       0.16   12.3   0.0    1.8  1  FAD_binding_6  Oxidoreductase FAD-binding domain


Domain annotation for each model (and alignments):
>> FAD_binding_8  FAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   74.0   0.0   2.6e-24   9.3e-21       6     107 ..     307     407 ..     303     409 .. 0.90
   2 ?   -2.9   0.0         2   7.3e+03      72     106 ..     590     648 ..     573     650 .. 0.58

  Alignments for each domain:
  == domain 1  score: 74.0 bits;  conditional E-value: 2.6e-24
  FAD_binding_8   6 kakvalleedliklkvskpkkslkykaGqyvyinipslsklfwqsHPFtiasapeddklslvikvksgltkklakkllsssk...kelenkkaklk 98 
                    +a++  l++++ +++v+ p    k+++Gq+v+++++s+ +l  qsHPFti+s p+d+kl+ ++++++g t++  +  ++ s    ++ +++++k +
     EEA22715.1 307 QATLTPLPGNVTRITVQDPL--IKWNPGQHVFLSCHSVAPL--QSHPFTIMSLPSDNKLEFLVRAEKGGTRRFFRFATKHSAllgETQSSDTSKRA 398
                    57888899********9998..6****************99..*****************************99999888777765566888899* PP

  FAD_binding_8  99 vlidGPYGa 107
                    v+i+GPYG+
     EEA22715.1 399 VFIEGPYGS 407
                    ********7 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 2
  FAD_binding_8  72 sgltkklakkllsssk........................kelenkkaklkvlidGPYG 106
                    sg+ +k+a+  +ss++                        + le+ + + +v++ GP G
     EEA22715.1 590 SGAAEKVASSTSSSPSttslvhmkgfkamtgrphprsiihYVLEQAEGESAVVVCGPRG 648
                    56666666666666555566556566555556556655556666666666666666655 PP

>> NAD_binding_6  Ferric reductase NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.5   0.1   9.4e-23   3.4e-19       1     155 [.     414     657 ..     414     658 .. 0.82

  Alignments for each domain:
  == domain 1  score: 69.5 bits;  conditional E-value: 9.4e-23
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxx.....xxxxxxxxxxxxxxx. RF
  NAD_binding_6   1 yenvllvagGiGitpfisilkdllkksk......kealktkkikliwvvressslewfkdvL....neleeekse.....gnieihiYlTseyea. 80 
                    +++v+l agG+G t+++++++d+++  k       +    k+i +iwv++++s+l+w++  L    + ++++k++     +++ei+iYlT ++   
     EEA22715.1 414 FDSVVLFAGGMGCTYTLPLMRDIVRAWKqepqrtMRLAAAKRIRFIWVIKSRSQLSWVEPELqsvlQDIQDLKQQhpdtdKEVEISIYLTCDEALe 509
                    799***********************998887776777889****************987665555788888888888999*********999885 PP

                    ........xxxxxxxxxxxxxxxxxxxx................................................................xxxx RF
  NAD_binding_6  81 ........edasdqlissiegenseslk................................................................qgvd 104
                              a+ ++++++++en++++k                                                                +   
     EEA22715.1 510 ksthptttVLAQRSSTEVSRNENIDEKKtlepenvvrpvsstskssgtnepsgcgvtrkccctttieneddisfvqkcncsgaaekvasstsS--- 602
                    6666665533334445555566666666999***********************************999999999999999988777664330... PP

                    xxxxxx..........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  NAD_binding_6 105 avsgtr..........nvkihfgRPnlkevlkdiaskhknssvgvfvCGppklvkevkklv 155
                         +            k   gRP  +++++ +  ++ +++ +v+vCGp++l+ +v+++v
     EEA22715.1 603 -----SpsttslvhmkGFKAMTGRPHPRSIIHYV-LEQAEGESAVVVCGPRGLAADVRQSV 657
                    .....1333447777789999*************.66666777999***********9987 PP

>> Ferric_reduct  Ferric reductase like transmembrane component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.2  13.2   1.9e-22   6.9e-19       1     124 [.     137     254 ..     137     255 .. 0.96

  Alignments for each domain:
  == domain 1  score: 68.2 bits;  conditional E-value: 1.9e-22
  Ferric_reduct   1 lGiaalillplalllalRnnflepltglsldklllfHkwlgvlafllallHvilyllnflrfsaldeerlldsllkkpynllGvlalllliilait 96 
                    +G++ + +lpl++lla+++n++   tg s+++l+++H+w++++++l a++H+++++  + rf       ++ +l +++y + G+ a+++l ++++t
     EEA22715.1 137 TGFMTICQLPLVILLAGKQNIIGLFTGSSYEQLNWYHRWVSRTLWLSATIHMAFWFRDYGRF-----HYIVTMLKTDYYTQHGFAAWIILSFIFLT 227
                    699*****************************************************999986.....6899************************* PP

  Ferric_reduct  97 SlkfirrrlsyelFyylHhllyvaylll 124
                    S+ ++r r++ye+F + H+++++ +l +
     EEA22715.1 228 SFAPVR-RWNYEFFVVQHIVTMAGFLAA 254
                    ******.**************9999876 PP

>> NAD_binding_1  Oxidoreductase NAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0     0.017        61       2      30 ..     420     450 ..     419     496 .. 0.75
   2 ?   -0.8   0.0      0.66   2.4e+03      19      64 ..     508     550 ..     498     567 .. 0.74
   3 ?    6.6   0.0    0.0034        12      82     108 ..     628     654 ..     600     655 .. 0.82

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.017
                    EEEGGGGHHHHHHHHHHHHH.CT.TCSEEEE CS
  NAD_binding_1   2 iagGtGiaPvrsvlrailee.ak.dktkvvl 30 
                     agG G ++++ ++r i+++ ++ +++ + l
     EEA22715.1 420 FAGGMGCTYTLPLMRDIVRAwKQePQRTMRL 450
                    69***************99964434444443 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.66
                    HHHCTTCSEEEEEEEESSGCGSTTHHHHHHHHHHCTTEEEEEEEES CS
  NAD_binding_1  19 leeakdktkvvlvyGnrteedllyreeleelakklpgrlkvvavvs 64 
                    le  k +++++ v + r++ ++  +e+++e ++  p++  v +v+s
     EEA22715.1 508 LE--KSTHPTTTVLAQRSSTEVSRNENIDEKKTLEPEN-VVRPVSS 550
                    44..4678889999999999999999999999988886.4666633 PP

  == domain 3  score: 6.6 bits;  conditional E-value: 0.0034
                    HHHHHHHSSTTEEEEEECSHHHHHHHH CS
  NAD_binding_1  82 leellslkkeethvyvCGppgMikavr 108
                    + ++l+  ++e+ v+vCGp+g++++vr
     EEA22715.1 628 IHYVLEQAEGESAVVVCGPRGLAADVR 654
                    444555567899***********9997 PP

>> FAD_binding_6  Oxidoreductase FAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   4.6e-05      0.16      25      74 ..     324     372 ..     317     409 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 4.6e-05
                    TS-----TT-EEEEEECETTCCEEEEEE.BSSTTECCEEEEEEE--TT-H CS
  FAD_binding_6  25 kqklglpvGqhvflrlkikgeaviRsYtpissenekGelellvkvypgGk 74 
                    +  ++  +Gqhvfl+++        ++t++s +++ ++le+lv+  +gG 
     EEA22715.1 324 DPLIKWNPGQHVFLSCHSVAPLQSHPFTIMSLPSD-NKLEFLVRAEKGGT 372
                    6678999**********888899*****9999875.79********8884 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (684 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       700  (0.0390429); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.61u 0.30s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 4555.92
//
Query:       EEA22716.1  [L=380]
Description: aminotransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    0.00014   21.5   0.7        0.3   10.9   0.0    3.5  3  Robl_LC7  Roadblock/LC7 domain


Domain annotation for each model (and alignments):
>> Robl_LC7  Roadblock/LC7 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.3   0.0   0.00096        17       5      30 ..      15      41 ..      12      54 .. 0.83
   2 ?    1.4   0.0     0.015   2.8e+02      33      60 ..     112     139 ..     106     144 .. 0.84
   3 !   10.9   0.0   1.7e-05       0.3      61      90 ..     184     212 ..     167     213 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.00096
                HHHHCCHHCTECEEEEEE.TTS-EEEE CS
    Robl_LC7  5 lleelqsvpgvrgalvvs.kdGlviat 30
                ll+ l+s pgv+ +l++s kdG +i +
  EEA22716.1 15 LLSHLTSRPGVQSTLILSrKDGSIIQS 41
                78999************9458988887 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.015
                 SSSS-HHHHHHHHHHHHHHHHHHHHHCT CS
    Robl_LC7  33 ldnddadqlAalasgllsaakaaarelg 60 
                 +++++a+ lAa++ +++  a+++a  l 
  EEA22716.1 112 YKPSQAETLAAHIFAFMTSASGLALSLS 139
                 57889***************99998776 PP

  == domain 3  score: 10.9 bits;  conditional E-value: 1.7e-05
                 SSSECEEEEEETTEEEEEEECTTTEEEEEE CS
    Robl_LC7  61 egelkelliegkkgelyltpagegalLvvl 90 
                 ++e+k l++++kk+e++++p  + +lL+v+
  EEA22716.1 184 DDEIKLLRLRTKKNEIVVVPDRK-YLLCVV 212
                 899********************.999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (380 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       657  (0.0366445); expected 358.6 (0.02)
Passed bias filter:                      404  (0.0225333); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.25s 00:00:00.74 Elapsed: 00:00:00.41
# Mc/sec: 2774.23
//
Query:       EEA22717.1  [L=1020]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1020 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       550  (0.0306766); expected 358.6 (0.02)
Passed bias filter:                      428  (0.0238719); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.70u 0.27s 00:00:00.97 Elapsed: 00:00:00.42
# Mc/sec: 7325.31
//
Query:       EEA22718.1  [L=317]
Description: dienelactone hydrolase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.8e-12   46.2   0.1    5.2e-12   45.8   0.1    1.2  1  DLH       Dienelactone hydrolase family


Domain annotation for each model (and alignments):
>> DLH  Dienelactone hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.8   0.1   2.9e-16   5.2e-12       2     216 ..      97     316 ..      96     317 .] 0.76

  Alignments for each domain:
  == domain 1  score: 45.8 bits;  conditional E-value: 2.9e-16
         DLH   2 daylatpknakkpvvvviqeifGvn.dnikdiserla....eeGYvalaPdlYarqa.........ldpndeaeaaraldelvskvaeekvlddlkaav 86 
                 ++y+ +p++a   +++vi +ifG   ++i + ++ la    +  Y + +Pd++ ++          +d+++++      ++ + + + +k+  +l +a 
  EEA22718.1  97 KTYVTGPADA-TRAILVIYDIFGFFpQTI-QGADILAtsdkDHKYRVYIPDFFEGEPadiswypptTDEHKQKLGNFFQTKAGPPAHIAKIPGILADAN 193
                 789*******.*************96444.34444441112678************9999987763333333333333344445555677777775555 PP

         DLH  87 aylksvpevstkkvgvvGfCmGGalalllaaevpevdaavafYGlspekeleeaakikapilalfgeeDefipadevekleealkaanvdlelkvYpga 185
                 + + s +    +  g+ G+C+G+++a l   ++ +++a +  ++  +  + e+a+++++pi  l + +De  +  +v+  e +l   +v+  ++ Y   
  EEA22718.1 194 KEASSGS--GFSSWGILGYCWGAKVANLTLGKDTAFKAGAQIHP--AMLDPEDAKNVSVPIALL-ASKDEDPA--AVKGYEANL---KVANLVETYHTQ 282
                 5555555..6689********************99*********..555567899*****9765.66666433..357888888...777789****** PP

         DLH 186 gHaFandsre...syneeaaedawervlelfkqv 216
                  H+ ++++++    ++++  e+++++vl++f+q+
  EEA22718.1 283 IHGWMAARANledPEVKKEYERGYRAVLDFFHQH 316
                 ******9999888999999************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (317 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       445  (0.0248201); expected 358.6 (0.02)
Passed bias filter:                      382  (0.0213063); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 2272.91
//
Query:       EEA22719.1  [L=440]
Description: C2H2 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.2e-09   36.5   9.6    0.00041   20.9   0.9    2.9  2  zf-C2H2_4    C2H2-type zinc finger
    2.7e-08   33.8  11.2    3.9e-05   23.9   0.8    3.6  4  zf-C2H2      Zinc finger, C2H2 type
    1.5e-06   28.4  15.8    3.1e-05   24.2   3.1    3.0  3  zf-H2C2_2    Zinc-finger double domain
     0.0014   18.4   7.6       0.22   11.3   0.2    2.7  2  zf-H2C2_5    C2H2-type zinc-finger domain
     0.0043   17.3   4.1      0.084   13.2   0.1    2.4  2  zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
  ------ inclusion threshold ------
      0.029   14.8  10.4       0.72   10.3   2.0    2.3  2  zf-C2HE      C2HE / C2H2 / C2HC zinc-binding finger
      0.038   14.0   0.5      0.038   14.0   0.5    2.1  2  zf-BED       BED zinc finger
      0.078   12.8   2.6        2.6    7.9   0.3    2.6  2  zf-C2H2_11   zinc-finger C2H2-type
      0.098   12.9   1.4        1.1    9.6   0.6    2.4  2  BolA         BolA-like protein
        5.6    7.2   9.1         25    5.1   2.1    2.4  2  zf-AN1       AN1-like Zinc finger


Domain annotation for each model (and alignments):
>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.0   2.2   9.8e-07    0.0018       1      23 [.     353     375 ..     353     376 .. 0.95
   2 !   20.9   0.9   2.3e-07   0.00041       1      21 [.     381     401 ..     381     403 .. 0.94

  Alignments for each domain:
  == domain 1  score: 19.0 bits;  conditional E-value: 9.8e-07
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlkth 23 
                 fkC++C++sF+++++L+rH + h
  EEA22719.1 353 FKCDQCPQSFNRNHDLKRHKRIH 375
                 8******************9998 PP

  == domain 2  score: 20.9 bits;  conditional E-value: 2.3e-07
   zf-C2H2_4   1 fkCpiCgksFsskkaLlrHlk 21 
                 f+C +C ksFs+k+aL+rHl+
  EEA22719.1 381 FPCNHCEKSFSRKDALKRHLL 401
                 89*****************96 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.4       8.7   1.6e+04      13      20 ..     164     171 ..     164     171 .. 0.84
   2 !   22.5   3.8     6e-08   0.00011       1      23 []     353     375 ..     353     375 .. 0.98
   3 !   23.9   0.8   2.2e-08   3.9e-05       1      21 [.     381     401 ..     381     402 .. 0.94
   4 ?   -1.0   0.1       1.7   3.1e+03       5      15 ..     404     414 ..     403     414 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 8.7
                 HHHHHHHH CS
     zf-C2H2  13 ksnLkrHi 20 
                 +++L++H+
  EEA22719.1 164 QYELNHHL 171
                 68999*96 PP

  == domain 2  score: 22.5 bits;  conditional E-value: 6e-08
                 EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHirtH 23 
                 +kC+ C++sF+r+++LkrH r+H
  EEA22719.1 353 FKCDQCPQSFNRNHDLKRHKRIH 375
                 8********************99 PP

  == domain 3  score: 23.9 bits;  conditional E-value: 2.2e-08
                 EEETTTTEEESSHHHHHHHHH CS
     zf-C2H2   1 ykCpdCgksFkrksnLkrHir 21 
                 ++C++C ksF+rk+ LkrH+ 
  EEA22719.1 381 FPCNHCEKSFSRKDALKRHLL 401
                 89*****************85 PP

  == domain 4  score: -1.0 bits;  conditional E-value: 1.7
                 TTTEEESSHHH CS
     zf-C2H2   5 dCgksFkrksn 15 
                 +Cgk   ++sn
  EEA22719.1 404 GCGKNTDTNSN 414
                 7***9999986 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.2   1.5   0.00011       0.2       5      25 ..     329     363 ..     325     364 .. 0.69
   2 !   24.2   3.1   1.7e-08   3.1e-05       1      25 [.     367     391 ..     367     392 .. 0.95
   3 ?   -2.6   0.1       5.1   9.2e+03       1       6 [.     395     400 ..     395     402 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00011
   zf-H2C2_2   5 Hir.kHt.............gekpyeCplCdkaFk 25 
                 H++ +H+             +++p++C+ C+ +F+
  EEA22719.1 329 HMYgSHPshhhqghgqsappNDRPFKCDQCPQSFN 363
                 665345555567776666555669**********8 PP

  == domain 2  score: 24.2 bits;  conditional E-value: 1.7e-08
   zf-H2C2_2   1 nLrrHirkHtgekpyeCplCdkaFk 25 
                 +L+rH r H + kp+ C  C k+F+
  EEA22719.1 367 DLKRHKRIHLSVKPFPCNHCEKSFS 391
                 69**********************8 PP

  == domain 3  score: -2.6 bits;  conditional E-value: 5.1
   zf-H2C2_2   1 nLrrHi 6  
                 +L+rH+
  EEA22719.1 395 ALKRHL 400
                 79***7 PP

>> zf-H2C2_5  C2H2-type zinc-finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   2.6   0.00058         1       1      24 [.     353     375 ..     353     376 .. 0.95
   2 !   11.3   0.2   0.00012      0.22       3      23 ..     383     402 ..     381     404 .. 0.91

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.00058
   zf-H2C2_5   1 YKCsqCDYstawksnLkRHlrrkH 24 
                 +KC+qC+ s  +  +LkRH r +H
  EEA22719.1 353 FKCDQCPQSFNRNHDLKRHKR-IH 375
                 9******************99.98 PP

  == domain 2  score: 11.3 bits;  conditional E-value: 0.00012
   zf-H2C2_5   3 CsqCDYstawksnLkRHlrrk 23 
                 C++C  s ++k+ LkRHl+ +
  EEA22719.1 383 CNHCEKSFSRKDALKRHLL-V 402
                 ******************9.5 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   0.7     0.016        29       2      22 ..     353     373 ..     352     373 .. 0.93
   2 !   13.2   0.1   4.7e-05     0.084       2      21 ..     381     400 ..     380     401 .. 0.94

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.016
                  CBBTTTTBBBSSHHHHHCCTT CS
  zf-C2H2_jaz   2 fYCvlCdKyFksenaldnHlk 22 
                  f C  C   F+  ++l+ H++
   EEA22719.1 353 FKCDQCPQSFNRNHDLKRHKR 373
                  99*****************86 PP

  == domain 2  score: 13.2 bits;  conditional E-value: 4.7e-05
                  CBBTTTTBBBSSHHHHHCCT CS
  zf-C2H2_jaz   2 fYCvlCdKyFksenaldnHl 21 
                  f C +C+K F+   al+ Hl
   EEA22719.1 381 FPCNHCEKSFSRKDALKRHL 400
                  78*****************7 PP

>> zf-C2HE  C2HE / C2H2 / C2HC zinc-binding finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   1.8    0.0011         2      35      57 ..     350     371 ..     331     378 .. 0.85
   2 ?   10.3   2.0    0.0004      0.72      36      58 ..     379     400 ..     372     403 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.0011
     zf-C2HE  35 ktpLkCtrCganfgnkfpkLKeH 57 
                 ++p+kC +C  + +n   +LK+H
  EEA22719.1 350 DRPFKCDQCP-QSFNRNHDLKRH 371
                 78********.888888****** PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.0004
     zf-C2HE  36 tpLkCtrCganfgnkfpkLKeHL 58 
                 +p+ C++C+++f +k  +LK+HL
  EEA22719.1 379 KPFPCNHCEKSFSRK-DALKRHL 400
                 799******666666.9*****9 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.2       4.4   7.9e+03      18      38 ..     354     371 ..     353     371 .. 0.75
   2 ?   14.0   0.5   2.1e-05     0.038      19      43 ..     383     405 ..     379     417 .. 0.91

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 4.4
                 EETTTTEE----SSTHHHHHH CS
      zf-BED  18 vCryCgkilsrgggttnLkrH 38 
                 +C  C   ++r+   + LkrH
  EEA22719.1 354 KCDQCPQSFNRN---HDLKRH 371
                 688888888887...677777 PP

  == domain 2  score: 14.0 bits;  conditional E-value: 2.1e-05
                 ETTTTEE----SSTHHHHHHH.HHS- CS
      zf-BED  19 CryCgkilsrgggttnLkrHL.rrkH 43 
                 C++C+k +sr+     LkrHL ++++
  EEA22719.1 383 CNHCEKSFSRK---DALKRHLlVKGC 405
                 ***********...9*****966665 PP

>> zf-C2H2_11  zinc-finger C2H2-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.1     0.019        34       5      26 ..     353     374 ..     349     375 .. 0.91
   2 ?    7.9   0.3    0.0015       2.6       7      24 ..     383     400 ..     381     402 .. 0.93

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.019
  zf-C2H2_11   5 cqCleCGlcftSqlsLsRHlfI 26 
                 ++C +C   f     L+RH +I
  EEA22719.1 353 FKCDQCPQSFNRNHDLKRHKRI 374
                 69*****************998 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.0015
  zf-C2H2_11   7 CleCGlcftSqlsLsRHl 24 
                 C +C   f+ + +L+RHl
  EEA22719.1 383 CNHCEKSFSRKDALKRHL 400
                 *****************9 PP

>> BolA  BolA-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.6   0.00062       1.1      15      53 ..     335     375 ..     326     381 .. 0.84
   2 ?    1.3   0.0      0.23   4.1e+02      36      54 ..     386     404 ..     377     409 .. 0.83

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00062
        BolA  15 eShkhaghaeag....getHFkvvivseaFegkslvarhRlvy 53 
                  Sh+h+gh   +    +   Fk+  + ++F+    ++rh+ ++
  EEA22719.1 335 PSHHHQGHG--QsappNDRPFKCDQCPQSFNRNHDLKRHKRIH 375
                 699*****6..224569***********************997 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.23
        BolA  36 vseaFegkslvarhRlvya 54 
                 + ++F+ k  ++rh lv  
  EEA22719.1 386 CEKSFSRKDALKRHLLVKG 404
                 5689**********99976 PP

>> zf-AN1  AN1-like Zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.1   2.1     0.014        25      12      29 ..     351     368 ..     345     376 .. 0.83
   2 ?    4.8   1.9     0.017        31      11      23 ..     378     390 ..     371     393 .. 0.82

  Alignments for each domain:
  == domain 1  score: 5.1 bits;  conditional E-value: 0.014
      zf-AN1  12 lpfkCryCgkvFClkHrl 29 
                  pfkC++C ++F  +H l
  EEA22719.1 351 RPFKCDQCPQSFNRNHDL 368
                 58**********888855 PP

  == domain 2  score: 4.8 bits;  conditional E-value: 0.017
      zf-AN1  11 flpfkCryCgkvF 23 
                   pf C++C+k+F
  EEA22719.1 378 VKPFPCNHCEKSF 390
                 457********99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (440 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       503  (0.0280551); expected 358.6 (0.02)
Passed bias filter:                      270  (0.0150594); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.50u 0.23s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 3159.90
//
Query:       EEA22720.1  [L=632]
Description: glutamate decarboxylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.4e-60  202.8   0.0      9e-60  202.3   0.0    1.1  1  Pyridoxal_deC  Pyridoxal-dependent decarboxylase conserved do
    0.00013   21.1   0.0    0.00022   20.3   0.0    1.4  1  Aminotran_5    Aminotransferase class-V


Domain annotation for each model (and alignments):
>> Pyridoxal_deC  Pyridoxal-dependent decarboxylase conserved domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  202.3   0.0     1e-63     9e-60      17     364 ..      71     393 ..      56     400 .. 0.91

  Alignments for each domain:
  == domain 1  score: 202.3 bits;  conditional E-value: 1e-63
                    H.HHHHHHHHHHCTGGGS--TTSTTBHCSSH....HHHHHHHHHHHHHT-BTSSTTTSHHHHHHHHHHHHHHHHHTT--GGGTCCT-EEEEESSHH CS
  Pyridoxal_deC  17 esleqilediekilapgvttwhspefhkllpagnslisllgdlLadainkngftweesPaltelevvvldwlaellglpeeflekegggvlqvgss 112
                    + + ++++  + +la++v t ++ +  +l+               +   kn  + +e+Pal+++  +++  +a l+++    +ek + g  +vgss
     EEA22720.1  71 D-ELDLDGRPNLNLASFVGTYMERQANALMA--------------ENLSKNLSDADEYPALMAMHARCVSIIASLWNAQ--PNEK-AIGSATVGSS 148
                    4.66677777777777777777555555555..............88889999************************98..4554.88******** PP

                    HHHHHHHHHHHHHHHHHHHHHTTTS.HHHHHCCEEEEEETTS-HHHHHHHHHHT-EEEEE--BTTTBB-HHHHHHHHHHHHCTT.EEEEEEEEBS- CS
  Pyridoxal_deC 113 estllallAartkvikemkekgkelkeaeildklvlytsdqahssvekaalvlgvklrvipldengklrgaalekaieedkekGlipffvvatlGt 208
                    e+++l++ A++++++++ k++gk+        ++++  +++a++++ek+a++++v+ r + + e+    g ++e   ++ +e+  ++  v ++lG+
     EEA22720.1 149 EAIMLGGKAMQRRWQEKRKAAGKD------ISRPNILMGANAQVALEKFARYFDVEARILDVSEKS-NFGLDPESVRKNIDEN--TI-GVFVILGS 234
                    ***********************9......889******************************965.8999999999999999..77.9******* PP

                    TTT-BB--HHHHHHHHHH......CT-EEEEE-TTGGGGGGSGGGGG.....GGTTGGGESEEEEECCCCTS--SS-EEEEESSCCGCHHHH-EEE CS
  Pyridoxal_deC 209 tvlgaFddlkelgdicek......ydlwlHvDAAyaGsaficpeirh.....llkgieradSitvnphKlllvlldcsalivkdkealqqalqlea 293
                    t++g ++ ++e+ +i+++      +d+++HvD A++G  fi+p+ +      + + ++r+ Si++++hK++lv+++ +++i++d++ l++ l++e 
     EEA22720.1 235 TYTGHYEPVEEISKILDEyeaetgHDIPIHVDGASGG--FIAPFAYAgggqkWNFELPRVRSINTSGHKFGLVYAGLGWIIWRDQSYLPKDLVFEL 328
                    *************************************..*****99999999******************************************** PP

                    CCCT.TTTTTSEECCCGSSSSSG..HHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTEEECST CS
  Pyridoxal_deC 294 eYLehedsdvaadlgtkaiplsr..rvrilklwfvlralGveglqnqirksvelakyleklirkderfeivae 364
                    +YL+          + +++++sr   ++i +++ ++  lG +g++  +++++ +a+ l   ++k++ f  v+ 
     EEA22720.1 329 HYLG-------GTEESYTLNFSRpgGQVIGQYYNLIH-LGFNGYRDIMENCLANARLLSIALEKTGWFTCVSS 393
                    ****.......66689*********************.**************************999988764 PP

>> Aminotran_5  Aminotransferase class-V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.3   0.0   2.4e-08   0.00022      51     171 ..     126     256 ..      87     279 .. 0.77

  Alignments for each domain:
  == domain 1  score: 20.3 bits;  conditional E-value: 2.4e-08
                  HHHHHHT-STGGGEE..EESSHHHHHHHHHHHCCCC-TTTSEEEEET.......TSHGGGTHHHHHHHHHHTEEEEEEEBETTSC..BEGGGHHHH-- CS
  Aminotran_5  51 kvaelinaeseeeii..ftsGtteainlvalslarslkpgdeivvte.......aehhanlvpwqelakrtgakvkvipldeege..ldldeleklln 137
                   +a l na+ +e+ i   t G++eai l  ++++r++++++++  ++       ++ +a++ + ++ a+   ++ +++ + e+ +  ld++ ++k+++
   EEA22720.1 126 IIASLWNAQPNEKAIgsATVGSSEAIMLGGKAMQRRWQEKRKAAGKDisrpnilMGANAQV-ALEKFARYFDVEARILDVSEKSNfgLDPESVRKNID 222
                  5777888888777775558888888888888888887777776543322233447888888.999999999999999999887773367999****** PP

                  TTEEEEEEESBETTTTEB--HHHHHHHHHHTT-E CS
  Aminotran_5 138 ektklvaithvsnvtGtiqpveeigklakkkgal 171
                  e+t  v++   s+ tG  +pveei k++ +++a 
   EEA22720.1 223 ENTIGVFVILGSTYTGHYEPVEEISKILDEYEAE 256
                  **************************99877653 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (632 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       565  (0.0315132); expected 358.6 (0.02)
Passed bias filter:                      508  (0.028334); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.29s 00:00:00.96 Elapsed: 00:00:00.49
# Mc/sec: 3853.84
//
Query:       EEA22721.1  [L=745]
Description: C6 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.7e-59  201.6   0.1    2.3e-59  201.1   0.1    1.1  1  Fungal_trans_2  Fungal specific transcription factor domain
    9.1e-07   28.9  12.6    1.5e-06   28.2  12.6    1.3  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  201.1   0.1   2.6e-63   2.3e-59      10     383 ..     315     744 ..     308     745 .] 0.89

  Alignments for each domain:
  == domain 1  score: 201.1 bits;  conditional E-value: 2.6e-63
  Fungal_trans_2  10 vapllspvpes.snpfrkvllplalsnkallhallalsafhlqskgpkdslereakrykslalkelqealaelsstlsrnekykdiLaaiLllcs 103
                     ++ +ls+ +   +np+r+++ p+a ++ al+ha+++++afh          +++   +++ ++++++++++++ + +  + + ++ La++L+l +
      EEA22721.1 315 TCGILSVKDGVtENPWRNLIWPMARESSALYHAVISMAAFHS---------SKDNPALRVFGMEHMRRSINFMVQGMG-QMQTDAALATTLSLAF 399
                     577888888888*****************************9.........8888999********************.999************* PP

  Fungal_trans_2 104 ieissgdvsdwrvhLeaatsliksrggs...kasssslsskarfllrifayldilssttlgrgpsfpseeyekllenkkeesdsgldplmGcsns 195
                     +e  + + s   +hL++a++l+++ + +    ++ s++  ++rfl +  +y+d+++++t+ ++   +     ++     e++ +++dplmGc + 
      EEA22721.1 400 AETWDQQTSTGIQHLKGARALMQQTLRTrvrRHPPSDELGRIRFLYNTWLYMDVIARITSMDEAETEEPGDPRFAIP--EDGVHDVDPLMGCATT 492
                     *******999999***************998888888888*********************8888887777777777..9999************ PP

  Fungal_trans_2 196 lilliseisrLarekrsarkdseleplsileeaseleqrllswkprssdlepdldeterasslskdltelfrlaaliylyrlvlglppsspevqe 290
                     l++l++++++L++++r+++k       +i ++a+el +++++w  ++++  p+++++e   s++   + ++r a l+yl+++v+++p+   +   
      EEA22721.1 493 LFPLMGHVANLVQRIRKSDKN----SFAIISHARELKNAIDRWVLPNHFNPPEDPQSELQDSIQ--TAYAYRWAILLYLHQAVPEIPSP--SSFI 579
                     *********************....*********************999888888887777777..6777*****************98..7777 PP

  Fungal_trans_2 291 lvkkllellellpsspvaiasLlWplFiaGceavdeddRdfvrrrleele.qsrlgnvrrarqvleevWrrrdd..................... 363
                     l ++ l+ll+++p s++ ++  ++plF+a ce +de+dR+++ +r+ +++ + r+gn+ r+ +v++evWrrrd                      
      EEA22721.1 580 LANNTLKLLATVPLSSRTNILHIFPLFVASCEFEDEEDREWIMQRWVAMQnRLRIGNIDRCVEVIREVWRRRDAakaerlrlrsrpgsrkgsmvi 674
                     99***************999999***************************55555******************8778888888888888888888 PP

  Fungal_trans_2 364 ...................................gee................kidWrdvmekkgwelll 383
                                                        + +                + +W  vm++ +we+ll
      EEA22721.1 675 hgehpsksgnvygtpidnnqalgglystspthkrqD-SiapiveeldfeqtvrgSHHWVGVMRDWNWEVLL 744
                     888888888887777777777766666666665550.05555555666677777999******99**9998 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.2  12.6   1.6e-10   1.5e-06       2      39 ..      61      98 ..      60      99 .. 0.92

  Alignments for each domain:
  == domain 1  score: 28.2 bits;  conditional E-value: 1.6e-10
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfysesskr 39
                +C++C+ k+ KCd+ kP+C++C k+n++C  y++  k+
  EEA22721.1 61 GCITCKAKRLKCDETKPSCQQCHKRNVTCGGYKKDFKW 98
                7*****************************99987665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (745 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       705  (0.0393218); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.67u 0.31s 00:00:00.98 Elapsed: 00:00:00.46
# Mc/sec: 4836.24
//
Query:       EEA22722.1  [L=143]
Description: ethanolamine utilization protein (EutQ), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-12   48.0   0.0    1.6e-12   47.5   0.0    1.2  1  EutQ      Ethanolamine utilisation protein EutQ
    8.4e-10   38.2   0.0    1.4e-09   37.5   0.0    1.3  1  Cupin_3   Protein of unknown function (DUF861)
    5.7e-06   25.9   0.0    8.5e-06   25.4   0.0    1.2  1  Cupin_2   Cupin domain
  ------ inclusion threshold ------
      0.019   14.9   0.0       0.03   14.3   0.0    1.3  1  Pirin     Pirin
      0.061   12.6   0.0      0.083   12.2   0.0    1.2  1  KduI      KduI/IolB family
      0.098   12.3   0.0       0.14   11.7   0.0    1.3  1  Cupin_1   Cupin
       0.22   11.2   0.0       0.45   10.2   0.0    1.4  1  Cupin_6   Cupin


Domain annotation for each model (and alignments):
>> EutQ  Ethanolamine utilisation protein EutQ
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.5   0.0   6.1e-16   1.6e-12      76     142 ..      65     133 ..      46     137 .. 0.85

  Alignments for each domain:
  == domain 1  score: 47.5 bits;  conditional E-value: 6.1e-16
        EutQ  76 rlgaGlmemke.ttfdwtlnydeidyvieGrldvlid.GrkvvaeaGdviliPkgskiefsvtdeakfl 142
                  ++ Gl ++++ t + +  +yde+ +++eG+ ++  + G+kv+a++Gdv + Pkgski f+++++   +
  EEA22722.1  65 PISCGLYRLEKgTPLVYEYTYDEMKIILEGEYEISDEtGQKVTAKPGDVFYFPKGSKITFTTPSYGLAF 133
                 5678888876525578999***************97659************************997555 PP

>> Cupin_3  Protein of unknown function (DUF861)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.5   0.0   5.3e-13   1.4e-09      21      64 ..      81     124 ..      61     128 .. 0.82

  Alignments for each domain:
  == domain 1  score: 37.5 bits;  conditional E-value: 5.3e-13
                 ECESSEEEEEEEECEEEEEETTTEEEEEETTEEEEE-TTEEECC CS
     Cupin_3  21 ltyeedEfcyileGevkvtpeggetvelraGDlvvlpkglsgtw 64 
                  +y++dE+  ileGe ++ +e g++v+ ++GD++++pkg++ t 
  EEA22722.1  81 YEYTYDEMKIILEGEYEISDETGQKVTAKPGDVFYFPKGSKITF 124
                 35777**********************************98775 PP

>> Cupin_2  Cupin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.4   0.0   3.3e-09   8.5e-06      20      53 ..      86     120 ..      70     129 .. 0.88

  Alignments for each domain:
  == domain 1  score: 25.4 bits;  conditional E-value: 3.3e-09
                 EEEEEEEESEEEEE.ECTEEEEEETTEEEEE-TT- CS
     Cupin_2  20 deffyVleGegelt.vdgeeveleaGdsvyfpagt 53 
                 de+ ++leGe e+    g++v+ ++Gd++yfp+g 
  EEA22722.1  86 DEMKIILEGEYEISdETGQKVTAKPGDVFYFPKGS 120
                 5999**********999****************96 PP

>> Pirin  Pirin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.0   1.2e-05      0.03      55      89 ..      89     123 ..      74     129 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 1.2e-05
                 EEEECSEEEEEETTS-EEEEETT-EEEEE-TT-EE CS
       Pirin  55 tylleGevehrDslGnkgvirpGdvqwmtAgsGiv 89 
                  ++leGe e  D++G+k + +pGdv     gs i+
  EEA22722.1  89 KIILEGEYEISDETGQKVTAKPGDVFYFPKGSKIT 123
                 679**********************8877776665 PP

>> KduI  KduI/IolB family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   3.2e-05     0.083      17      99 ..      56     130 ..      40     141 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 3.2e-05
                 CTCCCCCCCCBECCCEEEECHHCHHCHGCSEEEEEEEECCEEEECCTT.EEEEE-TTSSGGGS..EEEEE-TT--EEEEE.SST CS
        KduI  17 vtpesagweyvgfsvlkLaagesleletedrEvcvvllaGkvtvevageefeelgeRksvFegkpdavYvpkgakvtita.etd 99 
                  ++++   + ++  +++L++g+ l +e + +E+ + +l+G+ +++   e+ ++++++      + d+ Y pkg+k+t+t  + +
  EEA22722.1  56 SSEKNNAEKPISCGLYRLEKGTPLVYEYTYDEMKI-ILEGEYEISD--ETGQKVTAK------PGDVFYFPKGSKITFTTpSYG 130
                 4455556888999****************999876.58*******9..456666666......99************9984444 PP

>> Cupin_1  Cupin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   5.6e-05      0.14      55      94 ..      86     119 ..      70     134 .. 0.76

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 5.6e-05
                 -EEEEEEESEEEEEEEETTSS.EEEEEE.EETTEEEEE-TT CS
     Cupin_1  55 teiayvlqGegrvgfvvpgngnrdfhkk.lreGdvfvvPag 94 
                  e+ ++l+Ge      +++   ++ +k+  ++Gdvf++P+g
  EEA22722.1  86 DEMKIILEGEYE----ISD---ETGQKVtAKPGDVFYFPKG 119
                 556666666666....333...35677789**********9 PP

>> Cupin_6  Cupin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   0.00018      0.45      38      74 ..      90     125 ..      84     137 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00018
     Cupin_6  38 vvlrGscwlidpasgepvrLsagdvvllpggephvla 74 
                 ++l+G+  +  +++g+ v+ ++gdv  +p+g++ +++
  EEA22722.1  90 IILEGEYEIS-DETGQKVTAKPGDVFYFPKGSKITFT 125
                 799*******.565899***************99983 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (143 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       414  (0.0230911); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.40u 0.24s 00:00:00.64 Elapsed: 00:00:00.40
# Mc/sec: 1064.63
//
Query:       EEA22723.1  [L=669]
Description: serine/threonine protein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-60  205.0   0.0    8.5e-60  202.3   0.0    2.0  1  Pkinase        Protein kinase domain
    1.4e-28   99.9   0.3      6e-20   71.6   0.1    2.2  2  Pkinase_Tyr    Protein tyrosine kinase
    9.8e-05   22.4   6.7       0.26   11.2   0.1    3.9  4  APH            Phosphotransferase enzyme family
    0.00045   20.9   0.7     0.0013   19.4   0.7    1.8  1  Pkinase_C      Protein kinase C terminal domain
     0.0026   17.1   0.1      0.013   14.8   0.0    2.1  2  Kinase-like    Kinase-like
     0.0061   15.5   0.1       0.01   14.8   0.1    1.4  1  Haspin_kinase  Haspin like kinase domain
  ------ inclusion threshold ------
      0.058   12.7   0.0       0.15   11.4   0.0    1.7  1  Kdo            Lipopolysaccharide kinase (Kdo/WaaP) family


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  202.3   0.0   3.3e-63   8.5e-60       1     264 []     268     571 ..     268     571 .. 0.94

  Alignments for each domain:
  == domain 1  score: 202.3 bits;  conditional E-value: 3.3e-63
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHH.HHHHHHHHHHHHHSCTTB--EEEEEEESSEEEEEEE--TTEBHHHHHHHHSS--HH CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkke.kkvlrEikilkklkhpnivrlyevfeekdelylvleyveggeladllerkgslsee 98 
                 ++ l+++G+G++G+Vy a +k+t++  A+K+++k+   k +e +++l+E  il   k++ +v+l+++f++++++yl +eyv+gg++ +ll++ g+l ++
  EEA22723.1 268 FHILTQVGQGGYGQVYLAQKKDTREVCALKIMSKKLLFKLDEiRHILTERDILTAAKSDWLVKLLYAFQDDQQIYLAMEYVPGGDFRTLLNNTGVLHNR 366
                 67889********************************999999******************************************************** PP

                 HHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCS............................................ CS
     Pkinase  99 eakkiakqilegleylHskgiiHrDlKpeNiLidekgelKitDFGlakelesssk............................................ 153
                 +a+++++++++ ++ lH+ g iHrDlKpeN+Lid++g++K+tDFGla+ + +  k                                            
  EEA22723.1 367 HARFYVAEMFSCVDALHNLGYIHRDLKPENFLIDSTGHVKLTDFGLAAGMLNPGKiesmrikleevgntsvpfgrpmeqrtaaerregyrslrerevny 465
                 **************************************************999999******************************************* PP

                 BCTTTSCGGGS-HHHHTTSCBSHHHHHHHHHHHHHHHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCTSHH...HHH.TTS-HHHHHHHHHHT-SSGCC CS
     Pkinase 154 ltsfvgtseYlAPEvlkeneyskkvDvWslGvilyelltgkppfsgekgkekvekeldqlekilkilgetkeklpea.seiseeakdllkkllkkdpkk 251
                 ++s+vg+++Y+APEvlk+++y+ +vD+WslG++l+e l+g ppf+g + +e ++++l++    +k+l++   +++ + + +s+   dl+++l++ ++++
  EEA22723.1 466 ANSIVGSPDYMAPEVLKGEDYDFTVDYWSLGCMLFEALAGYPPFAGATVDE-TWQNLKR---WQKVLRK--PQYEDPnYFLSRRTWDLITRLVAAKETR 558
                 *********************************************777666.5555555...8999976..3444440456*************99998 PP

                 STTHHHHHTSGGG CS
     Pkinase 252 Rltaeellqhpyl 264
                    ++++ +h+y+
  EEA22723.1 559 FKNIQQIHEHEYF 571
                 889********98 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.6   0.1   2.3e-23     6e-20       3     153 ..     270     416 ..     268     429 .. 0.90
   2 !   26.2   0.0   1.6e-09   4.2e-06     168     242 ..     472     545 ..     456     564 .. 0.83

  Alignments for each domain:
  == domain 1  score: 71.6 bits;  conditional E-value: 2.3e-23
                  EEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTT..SSHHHHHHHHHHHHHHHTS-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHTCTT CS
  Pkinase_Tyr   3 lgkklGeGafGkVvegtlkgekekkevkVavKtlkee..ateeekeelleeakimkklkhpnivkllgvctkeepllivteyvkgGdLlkfLrkkeke 98 
                  + +++G+G +G+V+ ++ k    ++++ +a+K+++++   + +e +++l+e +i+++ k + +vkll +  +++++++ +eyv+gGd+++ L+++   
   EEA22723.1 270 ILTQVGQGGYGQVYLAQKK----DTREVCALKIMSKKllFKLDEIRHILTERDILTAAKSDWLVKLLYAFQDDQQIYLAMEYVPGGDFRTLLNNT--G 361
                  6789************999....6777778888865412567789***********************************************997..9 PP

                  TSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEETTEEEE-STTTHEET CS
  Pkinase_Tyr  99 kltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsenkvvkisDfGLardi 153
                   l+ ++   +++++ + ++ L++  ++Hrdl   N L++++ +vk++DfGLa  +
   EEA22723.1 362 VLHNRHARFYVAEMFSCVDALHNLGYIHRDLKPENFLIDSTGHVKLTDFGLAAGM 416
                  999999999999***************************************9866 PP

  == domain 2  score: 26.2 bits;  conditional E-value: 1.6e-09
                  GGGGS-HHHHHHSEEEHHHHHHHHHHHHHHHHTTSSGTTTTSHHHHHHHHHHTTEES-BBTTSBHHHHHHHHHHT CS
  Pkinase_Tyr 168 pvkWmapEslkekkftsksDvWsfGvllwEiftlgespypglkneevleklkegkrlekpekcpeelyelmkkcw 242
                  +  +mapE+lk + +    D Ws G +l+E +  g  p++g +  e+ ++lk+ +++ +  + ++  y l ++ w
   EEA22723.1 472 SPDYMAPEVLKGEDYDFTVDYWSLGCMLFEALA-GYPPFAGATVDETWQNLKRWQKVLRKPQYEDPNYFLSRRTW 545
                  5689****************************9.*****************887776555555555555555555 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.8   1.1    0.0022       5.7      74     174 ..     119     269 ..     101     270 .. 0.51
   2 !    6.4   0.0    0.0028       7.3       4     108 ..     273     385 ..     271     387 .. 0.63
   3 !   11.2   0.1    0.0001      0.26     164     196 ..     383     413 ..     367     414 .. 0.75
   4 ?   -1.8   0.0      0.91   2.3e+03      33      33 ..     558     558 ..     449     627 .. 0.55

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0022
                 EE----EE-SS...HHHHHHHHHHHHHHHHHHC.................................CHHCH.-STTTB-.................SHH CS
         APH  74 ieyvpgrsllr...klsaaqlpellealgefla.................................alhqvdpaalpla.................dfl 119
                 ++ vpg + +r   ++ ++  p+l+ +lg                                     +                             +fl
  EEA22723.1 119 YQQVPGSPTRRsnkENAPPNVPRLGKELGLNANsaavsrmeqyqqrdnmdsvrraqnqtmrgltpeE-----------LeklqtpkvkrlanvtqlYFL 206
                 5666666666655555555555555555555445555533333333333333333333333333331...........033333333333333333888 PP

                 CHTCCHHHHHHCHHHCC........CGCCTCC.HHHHHHHHHHHHHHHH--SSS-EEEE-SS-S CS
         APH 120 aqdlellrqlesatarl........laselld.lleeleeqvlaalaallpgelptvllHgDlh 174
                 +++ + l ++++++ r+         ++e++  ++e + +  l + +a+l+   +t+l HgD+h
  EEA22723.1 207 DHYFDILSYVHNRQTRYnqfkaaypAPPETPAeEYEPALQKYLGRERANLR-KRRTRLRHGDFH 269
                 888888888887766663344333322222224444444446666666666.59*********9 PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.0028
                 EE--.SSCEEEEEEETT--EE..EEEE-TT..S-HHHHHHHHHHHHHHHHTT-..B--B-CTTBS-EEETTEEEEEEE----EE-SS......HHHHHH CS
         APH   4 elsggasnrtylvttpagryv..lrrnppa..raaeeirrevallrlLakagv..pvPevlagdtddeeigllfalieyvpgrsllr......klsaaq 90 
                 +++ g + ++yl + +++r v  l++ +++      eir ++ + + L +a+    v  ++a  +dd++i+   +++eyvpg ++++       l+ ++
  EEA22723.1 273 QVGQGGYGQVYLAQKKDTREVcaLKIMSKKllFKLDEIRHILTERDILTAAKSdwLVKLLYA-FQDDQQIY---LAMEYVPGGDFRTllnntgVLHNRH 367
                 66777777899999988544334888777744222333333333355555555546755555.45666665...5788888877777766998888888 PP

                 HHHHHHHHHHHHCCHHCH CS
         APH  91 lpellealgeflaalhqv 108
                 ++ +++++ ++  alh++
  EEA22723.1 368 ARFYVAEMFSCVDALHNL 385
                 888888888888888876 PP

  == domain 3  score: 11.2 bits;  conditional E-value: 0.0001
                 S-EEEE-SS-SGGGEEEC..TTEEEEE---TT- CS
         APH 164 lptvllHgDlhpgNllvdpddgrvtGviDfeda 196
                    + +H+Dl+p N+l+d++++    + Df++a
  EEA22723.1 383 HNLGYIHRDLKPENFLIDSTGHVK--LTDFGLA 413
                 56789*************665444..7788776 PP

  == domain 4  score: -1.8 bits;  conditional E-value: 0.91
                 - CS
         APH  33 a 33 
                  
  EEA22723.1 558 R 558
                 0 PP

>> Pkinase_C  Protein kinase C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.7     5e-07    0.0013       1      46 []     590     641 ..     590     641 .. 0.94

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 5e-07
   Pkinase_C   1 vesdeDtsNFDpeFTeedprdtppddm.......pagspltssvqenFrGFtY 46 
                 ++s++D  +FD +F +e  + ++++ +        + +++++     F+GFt+
  EEA22723.1 590 LDSETDAGYFD-DFSNEADMAKYKEVHdkqrqleEMADRDEKMSKGLFVGFTF 641
                 58*********.******999999999999999999999999999*******9 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   5.2e-06     0.013     143     189 ..     366     411 ..     353     415 .. 0.91
   2 ?   -1.4   0.0      0.46   1.2e+03     227     254 ..     486     513 ..     482     533 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 5.2e-06
  Kinase-like 143 tiarlllTlqlirlaanLqakglvhgkftvdnllldekgglmlggft 189
                   +ar ++ +++   +  L+++g +h +++++n+l d  g ++l++f+
   EEA22723.1 366 RHARFYV-AEMFSCVDALHNLGYIHRDLKPENFLIDSTGHVKLTDFG 411
                  6888888.889999*******************************96 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.46
  Kinase-like 227 mthkldaWqlGlviyriwclklPltlat 254
                  + + +d W lG   +   + + P+  at
   EEA22723.1 486 YDFTVDYWSLGCMLFEALAGYPPFAGAT 513
                  66899*********99988888887765 PP

>> Haspin_kinase  Haspin like kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.1     4e-06      0.01     176     256 ..     333     415 ..     255     432 .. 0.70

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 4e-06
  Haspin_kinase 176 pdfyseqqlflvlllkdkGtdLeevklkswkqalsifwqivkiLyvaEt..kfeFEHRdLhldniLvdknlnvtlidlklsRl 256
                      f+++qq++l ++   +G+  + ++ + + +  +  + ++++ + +++  ++ + HRdL+ +n L+d++++v l d+ l+  
     EEA22723.1 333 YAFQDDQQIYLAMEYVPGGDFRTLLNNTGVLHNRHARFYVAEMFSCVDAlhNLGYIHRDLKPENFLIDSTGHVKLTDFGLAAG 415
                    55566666666666555555444445555555555555566666655542278899**********************99855 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   5.9e-05      0.15     129     166 ..     377     410 ..     349     422 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 5.9e-05
         Kdo 129 rliaklhragvnHadlyaknillqqeeeeeaeiwliDl 166
                   +  lh++g  H+dl + n+l++ ++    ++ l D+
  EEA22723.1 377 SCVDALHNLGYIHRDLKPENFLIDSTG----HVKLTDF 410
                 56889********************99....8888887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (669 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       835  (0.0465726); expected 358.6 (0.02)
Passed bias filter:                      598  (0.0333538); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.75u 0.31s 00:00:01.06 Elapsed: 00:00:00.48
# Mc/sec: 4152.50
//
Query:       EEA22724.1  [L=139]
Description: hypothetical protein PMAA_093410 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.029   14.9   0.1      0.045   14.3   0.1    1.4  1  Phage_connect_1  Phage gp6-like head-tail connector protein
      0.049   13.6   0.1      0.079   12.9   0.1    1.3  1  HEPN_AbiA_CTD    HEPN like, Abia C-terminal domain


Domain annotation for each model (and alignments):
>> Phage_connect_1  Phage gp6-like head-tail connector protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   0.1     5e-06     0.045      16      97 ..      26     108 ..      12     109 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 5e-06
  Phage_connect_1  16 dddDalLesliqaAeeyikdylgrkl.eadedgielpedlktavlelaahryenregtssdssegkslse.dnlpkglekiinq 97 
                      +  Da L+    +A++ i + + ++  +++++++++++  ++a+    + +y+++  t++ +  + + se +   ++l+ +inq
       EEA22724.1  26 NHRDARLSKAMTSATTNIDNSTAIPRlYGSPPPFDFTTA-NDAIIRHGVPDYNSSHSTINLQGASDTTSEvNDALQELSTCINQ 108
                      5689******************99999999999999777.9999999999*****99999999999999988888888888887 PP

>> HEPN_AbiA_CTD  HEPN like, Abia C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.1   8.8e-06     0.079      96     131 ..      78     113 ..      61     114 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 8.8e-06
  HEPN_AbiA_CTD  96 lshssselldkentskelkesikelsklideyieka 131
                     shs+ +l   ++t+ e+ ++++els+ i++ i+++
     EEA22724.1  78 SSHSTINLQGASDTTSEVNDALQELSTCINQVINNN 113
                    489*****************************9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (139 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       968  (0.0539907); expected 358.6 (0.02)
Passed bias filter:                      488  (0.0272185); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.41
# Mc/sec: 1005.72
//
Query:       EEA22725.1  [L=151]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.8e-24   85.6   0.0    1.1e-23   84.1   0.0    1.6  1  DUF1687   Protein of unknown function (DUF1687)


Domain annotation for each model (and alignments):
>> DUF1687  Protein of unknown function (DUF1687)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.1   0.0   6.1e-28   1.1e-23       1     127 [.       2     133 ..       2     135 .. 0.91

  Alignments for each domain:
  == domain 1  score: 84.1 bits;  conditional E-value: 6.1e-28
     DUF1687   1 FrtlqkspdvitlFhnakspaSnkllklLkkasakasekakedq...................ereefelevtekfPTlDQlktilsyvgkska..ksv 78 
                 Fr + k++d+it+Fh++++p S+++++lL++asa+a+e a+++                     r++fe+e+te +PT+DQl+ti +y+g++ +   +v
  EEA22725.1   2 FRIH-KTLDIITVFHKPSLPGSTRVVNLLRTASANATEIANSTPdqasdptpfakgssgadapLRDDFEVEITESLPTPDQLSTIIDYLGSKGVkpGAV 99 
                 7888.9***************************9999877755467****************99***************************98887778 PP

     DUF1687  79 lksafpelseilkkfkkdeeskkklkelvkedlFkrplvVDWdngkiaa 127
                 +++a  +++++lkk ++                F rp+vVDW ngk+++
  EEA22725.1 100 VQGAA-SKADALKKLSEI--------------GFARPIVVDWSNGKAVI 133
                 88877.999999999988..............8************9765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (151 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       307  (0.0171231); expected 358.6 (0.02)
Passed bias filter:                      278  (0.0155056); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.23s 00:00:00.62 Elapsed: 00:00:00.39
# Mc/sec: 1154.85
//
Query:       EEA22726.1  [L=343]
Description: rRNA processing protein Ipi1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.2e-28   97.4   0.3    6.8e-27   94.0   0.0    2.5  2  Ipi1_N    Rix1 complex component involved in 60S ribosome mat
     0.0073   16.5   1.1         18    5.9   0.0    4.0  5  HEAT      HEAT repeat
  ------ inclusion threshold ------
      0.015   15.8   4.2       0.59   10.7   0.3    3.9  4  HEAT_EZ   HEAT-like repeat
      0.021   15.2   0.5      0.092   13.1   0.1    2.1  2  HEAT_2    HEAT repeats


Domain annotation for each model (and alignments):
>> Ipi1_N  Rix1 complex component involved in 60S ribosome maturation
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.5      0.28   1.3e+03      55      95 ..      62      82 ..      35      93 .. 0.50
   2 !   94.0   0.0   1.5e-30   6.8e-27       2     102 .]     132     230 ..     131     230 .. 0.93

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.28
      Ipi1_N 55 nflallgwskeksskgstsakatsssssskktskksrlkvL 95
                + l+ll++++++                    + k  l +L
  EEA22726.1 62 HHLSLLSSKSDT--------------------QRKESLAHL 82
                233334332222....................333333333 PP

  == domain 2  score: 94.0 bits;  conditional E-value: 1.5e-30
      Ipi1_N   2 elaphaeslllyirsAmTHispdIredslkfLdllLevapeelvssa..wvktLnnflallgwskeksskgstsakatsssssskktskksrlkvLsvl 98 
                 +++ ha++ll yir++mTH+++dIr++s++ L +l+e a+ e+vs++  w+ktLn+fl+llgw++e+s k+s+++   ss +++++ +++ ++k+L++l
  EEA22726.1 132 DIEAHAAQLLPYIRAGMTHLAADIRSSSVEALGWLVETAGGEVVSCPggWIKTLNCFLSLLGWHTEESAKWSSNR---SSFGKAGS-EGRPMVKALHAL 226
                 6899***********************************************************888888888874...78888888.************ PP

      Ipi1_N  99 akfL 102
                 a+fL
  EEA22726.1 227 AEFL 230
                 ***8 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0       0.4   1.8e+03       6      22 ..      64      80 ..      64      84 .. 0.80
   2 !    5.6   0.1    0.0049        22       2      26 ..     103     127 ..     102     128 .. 0.87
   3 !    5.9   0.0    0.0041        18       1      25 [.     140     164 ..     140     169 .. 0.94
   4 ?   -1.9   0.0       1.3   5.8e+03      21      30 ..     220     229 ..     220     232 .. 0.78
   5 ?   -1.6   0.0         1   4.6e+03       5      24 ..     230     249 ..     226     250 .. 0.78

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.4
                HHHHT-SSHHHHHHHHH CS
        HEAT  6 lkllsDpspeVReaAak 22
                l+lls++s  +R+ ++ 
  EEA22726.1 64 LSLLSSKSDTQRKESLA 80
                5789********97765 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0049
                 HHHHHHHHT-SSHHHHHHHHHHHHH CS
        HEAT   2 lPlllkllsDpspeVReaAakaLga 26 
                 +P l+ ll D s +VR+  +k L +
  EEA22726.1 103 IPKLVPLLLDASNSVRAQLLKFLKT 127
                 799**************99887765 PP

  == domain 3  score: 5.9 bits;  conditional E-value: 0.0041
                 HHHHHHHHHT-SSHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLg 25 
                 llP +   +++ ++++R+++++aLg
  EEA22726.1 140 LLPYIRAGMTHLAADIRSSSVEALG 164
                 799**999****************8 PP

  == domain 4  score: -1.9 bits;  conditional E-value: 1.3
                 HHHHHHHHHC CS
        HEAT  21 akaLgalaev 30 
                 +kaL alae+
  EEA22726.1 220 VKALHALAEF 229
                 5788899886 PP

  == domain 5  score: -1.6 bits;  conditional E-value: 1
                 HHHHHT-SSHHHHHHHHHHH CS
        HEAT   5 llkllsDpspeVReaAakaL 24 
                 l   +s+++  + +a++ a+
  EEA22726.1 230 LRAGISSEETAIQDASVTAI 249
                 55567999999999999987 PP

>> HEAT_EZ  HEAT-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.0      0.29   1.3e+03      35      53 ..      65      83 ..      58      84 .. 0.88
   2 ?   10.7   0.3   0.00013      0.59      21      47 ..      94     120 ..      86     128 .. 0.86
   3 ?    1.6   0.0     0.092   4.1e+02      21      53 ..     132     164 ..     125     164 .. 0.87
   4 ?    1.0   0.0      0.15   6.6e+02      16      52 ..     213     249 ..     212     250 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 0.29
     HEAT_EZ 35 alLnddsdeVRaaAagaLg 53
                +lL+++sd+ R+ ++ +L+
  EEA22726.1 65 SLLSSKSDTQRKESLAHLT 83
                799********99988885 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 0.00013
     HEAT_EZ  21 llqplvpeilpaLlalLnddsdeVRaa 47 
                  l++ v++++p L++lL d s +VRa+
  EEA22726.1  94 PLPQPVSVMIPKLVPLLLDASNSVRAQ 120
                 4778899******************86 PP

  == domain 3  score: 1.6 bits;  conditional E-value: 0.092
     HEAT_EZ  21 llqplvpeilpaLlalLnddsdeVRaaAagaLg 53 
                 +++ +  ++lp+  a++++  +++R  ++ aLg
  EEA22726.1 132 DIEAHAAQLLPYIRAGMTHLAADIRSSSVEALG 164
                 56778899*********9999999999999998 PP

  == domain 4  score: 1.0 bits;  conditional E-value: 0.15
     HEAT_EZ  16 ggepellqplvpeilpaLlalLnddsdeVRaaAagaL 52 
                 g e++ + +++ ++  +L a+ ++++ +++ a++ a+
  EEA22726.1 213 GSEGRPMVKALHALAEFLRAGISSEETAIQDASVTAI 249
                 5667777788888999999999999999999999987 PP

>> HEAT_2  HEAT repeats
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.1     2e-05     0.092       1      58 [.     103     166 ..     103     176 .. 0.84
   2 ?   -1.2   0.0       0.6   2.7e+03      33      55 ..     227     249 ..     216     256 .. 0.69

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2e-05
      HEAT_2   1 ldaLlqalendpdpevrraairaLg.......rignpealpaLvellededpavRraaaeaLgai 58 
                 +++L+ +l  d++  vr++ ++ L        + +  ++lp+++  +++  +++R   +eaLg++
  EEA22726.1 103 IPKLVPLL-LDASNSVRAQLLKFLKtlptadiEAHAAQLLPYIRAGMTHLAADIRSSSVEALGWL 166
                 58899999.79**************55555444444477************************97 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.6
      HEAT_2  33 lpaLvellededpavRraaaeaL 55 
                  + L+  +++e++a++ a ++a+
  EEA22726.1 227 AEFLRAGISSEETAIQDASVTAI 249
                 44555666777777777777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (343 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       515  (0.0287244); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.46u 0.23s 00:00:00.69 Elapsed: 00:00:00.40
# Mc/sec: 2598.71
//
Query:       EEA22727.1  [L=383]
Description: C6 finger domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-08   34.7   6.9    2.1e-08   34.1   6.9    1.2  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.1   6.9   1.2e-12   2.1e-08       2      38 ..      44      84 ..      43      86 .. 0.87

  Alignments for each domain:
  == domain 1  score: 34.1 bits;  conditional E-value: 1.2e-12
                S-HHHHHCT---ST....SSSS-HHHHHCTHHHCCCCTCCC CS
     Zn_clus  2 aCdnCrkkKvKCda....kkPaCsnCkklnleCtfysessk 38
                aC +Cr++K++C       ++ C nC++l++eC+fy+  ++
  EEA22727.1 44 ACVHCRRRKIRCLVaaddSQGRCENCIRLRKECQFYPVDQQ 84
                9***********8876667777**************98665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (383 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      245  (0.013665); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 2501.51
//
Query:       EEA22728.1  [L=115]
Description: hypothetical protein PMAA_093450 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
       0.13   12.2   0.0       0.15   12.0   0.0    1.1  1  Serglycin        Serglycin
       0.19   11.5  12.9       0.26   11.1  12.9    1.2  1  Gly-zipper_YMGG  YMGG-like Gly-zipper


Domain annotation for each model (and alignments):
>> Serglycin  Serglycin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   1.7e-05      0.15      51     109 ..      29      90 ..       4     100 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 1.7e-05
   Serglycin  51 kgpvfdllpdesnrilpprtd...pflmeksqnlndvfplsedysgsgsGsGsGsGsgsgsg 109
                 k ++  l+pde++ ilp + d    +  ++s + n  +  s   s +g+  G+G G++ g g
  EEA22728.1  29 KSTLRHLPPDEQEAILPIKEDekpLYGQMQSTETNGGVGQSARASAAGAVVGAGVGADLGPG 90 
                 6677789**************54334456777788889999999999999999999887655 PP

>> Gly-zipper_YMGG  YMGG-like Gly-zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1  12.9   2.9e-05      0.26       4      45 ..      66     114 ..      63     115 .] 0.62

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 2.9e-05
                      .XXXXXXXXXXXXXXXXXXXXXXXXX.......XXXXXXXXXXXXXXX- CS
  Gly-zipper_YMGG   4 vrGAaiGAaaGAvvGaliGsgggkGA.......aiGAaaGalaGgaiGa 45 
                      v++ a   aaGAvvGa +G++ g GA       + +A aG  +G a G+
       EEA22728.1  66 VGQSARASAAGAVVGAGVGADLGPGAttskkdqGMMASAGEMVGKALGR 114
                      556666666666666666633333433333333***********99987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (115 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       414  (0.0230911); expected 358.6 (0.02)
Passed bias filter:                      275  (0.0153383); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.47
# Mc/sec: 732.60
//
Query:       EEA22729.1  [L=854]
Description: GATA transcriptional activator AreA [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-16   59.5   2.3    3.1e-16   58.7   2.3    1.5  1  GATA      GATA zinc finger
    1.6e-12   47.0   2.6    3.1e-12   46.1   2.6    1.5  1  DUF1752   Fungal protein of unknown function (DUF1752)
    0.00032   21.3   3.1    0.00057   20.5   0.2    3.1  2  AreA_N    Nitrogen regulatory protein AreA N terminus


Domain annotation for each model (and alignments):
>> GATA  GATA zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.7   2.3   5.3e-20   3.1e-16       1      35 [.     619     652 ..     619     653 .. 0.98

  Alignments for each domain:
  == domain 1  score: 58.7 bits;  conditional E-value: 5.3e-20
        GATA   1 CsnCgttkTplWRrgpdgnksLCnaCGlyykkkgl 35 
                 C+nC t +TplWRr+p+g++ LCnaCGl+ k++g+
  EEA22729.1 619 CTNCFTQTTPLWRRNPEGQP-LCNACGLFLKLHGV 652
                 ********************.************97 PP

>> DUF1752  Fungal protein of unknown function (DUF1752)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.1   2.6   5.2e-16   3.1e-12       1      28 []      61      88 ..      61      88 .. 0.97

  Alignments for each domain:
  == domain 1  score: 46.1 bits;  conditional E-value: 5.2e-16
     DUF1752  1 lWkyytkkkkdlpngeRLENlSWRlWnk 28
                +Wk+y+++k++lpn+eR+ENl+WR++++
  EEA22729.1 61 IWKLYSRTKSQLPNQERMENLTWRMMAM 88
                7*************************96 PP

>> AreA_N  Nitrogen regulatory protein AreA N terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.5   0.2   9.5e-08   0.00057      61      94 .]      16      50 ..      10      50 .. 0.87
   2 ?   -3.0   0.2         2   1.2e+04      36      51 ..     127     140 ..     100     158 .. 0.51

  Alignments for each domain:
  == domain 1  score: 20.5 bits;  conditional E-value: 9.5e-08
      AreA_N 61 PadsaqvqdgllqdslfPewkagaPra.GvdsPde 94
                P + + ++ +ll d++fP+w+ g+Pr+  vd+Pde
  EEA22729.1 16 PIEDSIAKTALLGDTVFPDWQDGTPRDdAVDGPDE 50
                555668999*****************6379****8 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 2
      AreA_N  36 snnfshlpatssqlsd 51 
                 +n+ ++  ++s+  s 
  EEA22729.1 127 ANQSNN--TASASASA 140
                 222211..12222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (854 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       816  (0.0455129); expected 358.6 (0.02)
Passed bias filter:                      410  (0.022868); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.68u 0.27s 00:00:00.95 Elapsed: 00:00:00.44
# Mc/sec: 5767.71
//
Query:       EEA22730.1  [L=492]
Description: N,N-dimethylglycine oxidase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.7e-31  109.4   2.3    4.7e-30  105.3   2.3    2.1  1  DAO              FAD dependent oxidoreductase
    0.00041   20.6   0.0    0.00093   19.4   0.0    1.6  1  TrkA_N           TrkA-N domain
     0.0013   18.0   1.9       0.39    9.9   0.0    2.5  2  Pyr_redox_2      Pyridine nucleotide-disulphide oxidoreductas
      0.009   16.2   0.1      0.023   14.9   0.1    1.7  1  NAD_binding_8    NAD(P)-binding Rossmann-like domain
  ------ inclusion threshold ------
      0.028   13.3   0.5        4.3    6.1   0.0    2.1  2  Trp_halogenase   Tryptophan halogenase
      0.037   14.3   0.1        0.1   12.8   0.0    1.8  2  Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding doma


Domain annotation for each model (and alignments):
>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  105.3   2.3   1.6e-33   4.7e-30       2     350 ..       5     445 ..       4     447 .. 0.71

  Alignments for each domain:
  == domain 1  score: 105.3 bits;  conditional E-value: 1.6e-33
                 EEEECTSHHHHHHHHHH......HHTT...EEEEESSSSTTSSGGGSSEEEEESSSSTHHSTHHHHHHHHHHHHHHHHHHHHHSSTTSEEEEEEEEEES CS
         DAO   2 vviiGGGiiGlstAyeL......arrg...VtllekgdiagsgaSgrnsgllhsglrylpeaselarlslealeelreleeelgididyrrtGllslaa 91 
                 ++i+GGGi+G++ A++L      +      ++l++ +  + +g++ ++ g + + +   ++   l rl+ ++++e++++ +      +++  G +   a
  EEA22730.1   5 IIIVGGGIVGSALAHFLssssssS--SrrkIILIDNSLTPLQGSTAHAPGYVGQ-FN--ESS-TLTRLAIDSVAEYAKIPN------GFEVLGGIEAVA 91 
                 89***************5544441..1557*******99999**********88.53..332.456888888777777773......5999*****999 PP

                 SHHHHHHHHHHHHHHHHTTTTEEEEEHHHHHHHSTT.ST..TTSEEEEETTEEEEEHHHHHHHHHHHHHHTT-EEEES...............ECEEEE CS
         DAO  92 deeelealdkllallleagldaelldaeevrelepa.lp..gllgalfypdtgqvdpakltaalaraaealGveileg...............tevtgl 172
                 ++e   +l+ + +++ + gl a+++++++++ l+p  ++  ++++al++ ++g++++ + ta+++++a+++Gve++eg                     
  EEA22730.1  92 TQEGISRLQTRCDAAVQRGLSARIITPAQAAGLAPDlVRqdDIQAALYFATDGVANATAITAFYQQQARRKGVEFVEGvvggirygedwevvgV----- 185
                 999999999999999889*****************873256*************************************5555555555444443..... PP

                 EEEETCEEEEE...........EECTEEEE...............EEEEEEE--GGGHH.HHHTTCTT..TSEEEEEEEEEEEEEECCTHSTGSGCSEE CS
         DAO 173 eeedgkvwgve...........rttpgend...............aadavVnaaGawsd.llgllkel..dlpispvrgqvlvlkplseklvspaailp 242
                           e           +      +               + +++++a+G+w++ l     +l  ++pi pv + ++ +k+        a  ++
  EEA22730.1 186 ----------EveevvkedsneV------EgndsqtvkrkvtriiETNTLILATGIWTQdLC---ADLniPIPIIPVAHPYMYIKHDRP-----ADDDT 260
                 ..........2444333222110......12233344445555444466**********666...4443357************55433.....21122 PP

                 EEE.EEETTTTEEEEEE..............................................TTSEEEEEESSE................EETTCSST CS
         DAO 243 vpe.tdddgrgvyvtpr..............................................kdgrvlvGgtad................eesgdddp 278
                   + ++ +  g+ + p+                                                       ++d                + ++    
  EEA22730.1 261 SSQsNISPRSGTLLSPSgslssssspsplsnttqksplfsrlnnnnnkpspwvrypehqvyarD--------HGDfygvgtydhgpamycePSDHVAIG 351
                 2224778888888888777777777788888888888888888888888888888544444443........333555555556999976444444448 PP

                 SCSHHHHHHHHHHHHHHSGGG...................CGEE.....EEEEEEEE.ETTSSEEEEEEETEEEEEEEEECTTTHHHHHHHHHHHHH CS
         DAO 279 evdeedidellealrklfPql...................gdvl.....rkwaGlrp.lpdglpligetpgvkglylatGhsghGltlapatGklla 350
                 +  +e +   le++++l+P l                   g+v+      k+ Gl   +pd+lpl g++ g kglyl++      +t+a+++++ +a
  EEA22730.1 352 PWHDEVFTSALERAKTLIPILathdgekdpsmvgrgvgggGRVStampeTKFNGLFSmTPDNLPLAGKVDGRKGLYLCAAV---WVTHAAGAARFVA 445
                 999999************995444555444455444444433443333248888777459********88999*****998...9999999999887 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.4   0.0   3.1e-07   0.00093       1      63 [.       5      71 ..       5      74 .. 0.90

  Alignments for each domain:
  == domain 1  score: 19.4 bits;  conditional E-value: 3.1e-07
                EEEES-SHHHHHHHHHHHHTT.....EEEEEEESSHHHHHHHHHTTSEEEES-TTSHHHHHHTTGGGE CS
      TrkA_N  1 iiiiGlGrvGrslaeeLsegg.....kdvvvidkdeerveelreeglevvvgdatdeevLeeagieka 63
                iii+G G vG++la+ Ls+++     +++++id++   ++  ++  ++ +vg+  + ++L ++ i+++
  EEA22730.1  5 IIIVGGGIVGSALAHFLSSSSssssrRKIILIDNSLTPLQGSTA-HAPGYVGQFNESSTLTRLAIDSV 71
                8******************5559***77*******999999765.4689*************999975 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.9   0.0   0.00013      0.39       3      77 ..       5      91 ..       3     113 .. 0.66
   2 !    6.5   0.5    0.0014       4.3      83     114 ..     196     230 ..     134     239 .. 0.46

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00013
                 EEEE--SHHHHHHHHHHHH.....HTS-EEEEETTHCHHHCSHHHHCHHHHHHHHHHHHH.........HHHHCHHHHCCCCHCCTCEE CS
                 xxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.........xxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  3 vvviGgGpAGlaaaltlaq.....agakvtlvelegtclnggcllskallgvaedaeias.........evvkklnqgielllgeevvk 77
                 ++++GgG+ G a+a++l+      +  k++l+ ++  ++++g    +a   v+++ e  +          +  k+ +g+e+l g e+v+
   EEA22730.1  5 IIIVGGGIVGSALAHFLSSsssssSRRKIILI-DNSLTPLQGSTA-HAPGYVGQFNESSTltrlaidsvAEYAKIPNGFEVLGGIEAVA 91
                 899*************9999988779999999.666666654443.3333333333333355777777755566677777666655444 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0014
                  EEEEETEEEC...........TCEEEEEESEEEE---EEE-BC CS
                  xxxxxxxxxx...........xxxxxxxxxxxxxxxxxxxxxx RF
  Pyr_redox_2  83 kkvklekkke...........gdeekiaydklvlAtGssprdl 114
                           e           + ++ i+ ++l+lAtG ++ dl
   EEA22730.1 196 N--------EvegndsqtvkrKVTRIIETNTLILATGIWTQDL 230
                  1........1112222223334455555566666666555554 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.1   7.5e-06     0.023       1      28 [.       7      39 ..       7      56 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 7.5e-06
                   EE--SHHHHHHHHHHHCC.....TEEEEEE-SS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLaka.....gfdvlllekr 28
                   IvG+G+ G+++A++L+       ++++ l++++
     EEA22730.1  7 IVGGGIVGSALAHFLSSSsssssRRKIILIDNS 39
                   9**************974344557788888875 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   0.0    0.0014       4.3       2      34 ..       5      39 ..       4      47 .. 0.80
   2 ?    5.6   0.1     0.002       5.9     151     194 ..     146     189 ..     103     201 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0014
                    EEEE--SHHHHHHHHHHHHHTTTS..SEEEEEE-S CS
  Trp_halogenase  2 ivivGGGtaGwlaAaalakalkgk..levtlvese 34
                    i+ivGGG+ G+  A  l+   + +   ++ l++ +
      EEA22730.1  5 IIIVGGGIVGSALAHFLSSSSSSSsrRKIILIDNS 39
                    9****************988766556778888765 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.002
                     E-HHHHHHHHHHHHHHCT-EEEE--EEEEEE-TTS-EEEEEETT CS
  Trp_halogenase 151 ldaalyakfLrrvaearGvtrvegkvvevqldedgrveslrled 194
                      +a     f ++ a ++Gv+ veg v  ++  ed +v ++++e+
      EEA22730.1 146 ANATAITAFYQQQARRKGVEFVEGVVGGIRYGEDWEVVGVEVEE 189
                     68888999**********************99998888887755 PP

>> Sacchrp_dh_NADP  Saccharopine dehydrogenase NADP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   3.5e-05       0.1       1      44 [.       5      50 ..       5      75 .. 0.85
   2 ?   -2.8   0.0       2.3     7e+03      11      39 ..     122     150 ..     119     164 .. 0.68

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 3.5e-05
                     EEEE--SHHHHHHHHHHHCTCCT-G..EEEEEESSHHHHHHHHCHH CS
  Sacchrp_dh_NADP  1 vliiGaGsvGqavaellarhfdvda..eitvadrskeklealaaka 44
                     ++i+G+G vG+a+a+ l+ +++ ++  +i+++d s++ l+   a+a
       EEA22730.1  5 IIIVGGGIVGSALAHFLSSSSSSSSrrKIILIDNSLTPLQGSTAHA 50
                     89******************9998899********99988877766 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 2.3
                      HHHHHHHHCTCCT-GEEEEEESSHHHHHH CS
  Sacchrp_dh_NADP  11 qavaellarhfdvdaeitvadrskeklea 39 
                       ++a++l+r++d++a +  a+   +++ a
       EEA22730.1 122 AGLAPDLVRQDDIQAALYFATDGVANATA 150
                      57888999999886666665555555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (492 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       513  (0.0286129); expected 358.6 (0.02)
Passed bias filter:                      413  (0.0230353); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.62u 0.24s 00:00:00.86 Elapsed: 00:00:00.43
# Mc/sec: 3448.59
//
Query:       EEA22731.1  [L=394]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.6e-36  124.7   0.0    6.3e-36  123.9   0.0    1.4  1  Pyrid_oxidase_2  Pyridoxamine 5'-phosphate oxidase


Domain annotation for each model (and alignments):
>> Pyrid_oxidase_2  Pyridoxamine 5'-phosphate oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.9   0.0   3.5e-40   6.3e-36       6     168 ..     173     366 ..     168     368 .. 0.87

  Alignments for each domain:
  == domain 1  score: 123.9 bits;  conditional E-value: 3.5e-40
                      HHHHHHHHHHH-SEEEEEEE--SGG................GTTSEEEEEEE-BSSSTT.---S--EEEE-TTSHHHHHHHH--EEEEEEEGGG CS
  Pyrid_oxidase_2   6 aAavARtlvhreslgtlsTisttkd................iegapfanvvsisdgaad.dstGnpylllvdidstaqniqknsklsltiseeq 82 
                      +  +AR+l+ ++s+g  sT+ +++d                ++g+++ + ++i+d  +   ++Gnp+ll + +++t+qni+k+s++sl+i +  
       EEA22731.1 173 SVLMARRLLAKSSVGIASTVYQHSDsssapiayhhapqpagLQGVSISLPEYIADCSEVdGNNGNPILLGLYVSTTFQNIAKGSNISLSIDWWS 266
                      6679****************8877778899999999******************8766459********************************* PP

                      SSHHHHH...T--TTSTTS-EEEEEEEEEE--......TTTHHHHHHHHHHH-GGGGGS-GG.....G--EEEEEEEEEEEEE-SSSS-EEE.. CS
  Pyrid_oxidase_2  83 tptckkk...kvdpesptcarvsltGklekve......seekklaekcllsrHpdakkWlpgn..sihkshfvkLeveeiylvggFGdrayi.. 163
                      + + +++   ++  ++++++r+s+ G++e+++      s  k+ +e+c++ +Hpdak W p+n  s+h+ ++++++v+++y+vggFGd ++i  
       EEA22731.1 267 HVKDTDPvypGFPLSEAGLPRISMLGYVERLDlssatsSATKEGLEECFFATHPDAKVWAPRNpdSPHSGFWARMVVTQVYWVGGFGDLQQIgw 360
                      99775543333444555999***********88887755555559*******************************************999977 PP

                      .-HHHH CS
  Pyrid_oxidase_2 164 .daeeY 168
                       ++ ++
       EEA22731.1 361 vNVTDW 366
                      776666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (394 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       295  (0.0164538); expected 358.6 (0.02)
Passed bias filter:                      266  (0.0148363); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.36s 00:00:01.04 Elapsed: 00:00:00.59
# Mc/sec: 2016.37
//
Query:       EEA22732.1  [L=702]
Description: G1/S-specific cyclin Pcl5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-06   28.3   0.0      2e-06   28.3   0.0    2.6  4  Cyclin    Cyclin
    0.00035   20.3   0.0    0.00083   19.1   0.0    1.7  1  Cyclin_N  Cyclin, N-terminal domain


Domain annotation for each model (and alignments):
>> Cyclin  Cyclin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.3   1.3         2   1.8e+04      31      58 ..      28      55 ..      13      65 .. 0.39
   2 !   28.3   0.0   2.2e-10     2e-06     112     161 .]     239     288 ..     197     288 .. 0.93
   3 ?   -1.9   0.0      0.41   3.7e+03      58      79 ..     419     440 ..     362     447 .. 0.75
   4 ?   -3.4   1.0       1.2   1.1e+04      22      40 ..     488     506 ..     473     538 .. 0.50

  Alignments for each domain:
  == domain 1  score: -4.3 bits;  conditional E-value: 2
                ---T.....................T-- CS
      Cyclin 31 nlensqkqssshtkttfaqtpkessFat 58
                 +  s   sss+   +++  + +ss ++
  EEA22732.1 28 SSVGSSASSSSSSIFSLDCVSTQSSISS 55
                3333333333333333333333333333 PP

  == domain 2  score: 28.3 bits;  conditional E-value: 2.2e-10
                 HHHHHHHHHHHHHH-SS---HHHHHHHHTS-HHHHHHHHHHHHHHTTT-- CS
      Cyclin 112 RllivallvatKflvDlsysnekfakvggislkELnkLEidFlflvdFdl 161
                 R+ ++al  a+K l+D  ys   ++k+ g++ +E+n+ E+ Fl  vd++l
  EEA22732.1 239 RMFLAALILASKYLQDRNYSARAWSKISGLQTQEINQNEMMFLQAVDWKL 288
                 999********************************************986 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 0.41
                 -SS--SS-HHHHHHHHHHHTT- CS
      Cyclin  58 tkavpaisigsylsrlqkfges 79 
                 +   pa+s++  +sr  +f+++
  EEA22732.1 419 AASTPAVSVRGTCSRRPSFASA 440
                 4456999999999999888875 PP

  == domain 4  score: -3.4 bits;  conditional E-value: 1.2
                 ------------T...... CS
      Cyclin  22 atasadsksnlensqkqss 40 
                     +d++  +++s + ss
  EEA22732.1 488 ESMVSDVSTISSRSSRSSS 506
                 3333333333333333333 PP

>> Cyclin_N  Cyclin, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   9.3e-08   0.00083      75     126 ..     239     288 ..     214     289 .. 0.94

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 9.3e-08
                 HHHHHHHHHHHHHHSSS---HHHHHHHTTTSS-HHHHHHHHHHHHHHTTT-- CS
    Cyclin_N  75 lvgatcLllAaKveeisppkledlvyitdeafteeeilemErliLetLnfdl 126
                 ++++++L+lA+K+ +++  +++ +  i++   + +ei++ E+ +L++ +++l
  EEA22732.1 239 RMFLAALILASKYLQDRNYSARAWSKISG--LQTQEINQNEMMFLQAVDWKL 288
                 7899*************99*****99976..999****************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (702 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       589  (0.0328518); expected 358.6 (0.02)
Passed bias filter:                      262  (0.0146132); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.76u 0.36s 00:00:01.12 Elapsed: 00:00:00.56
# Mc/sec: 3798.62
//
Query:       EEA22733.1  [L=702]
Description: G1/S-specific cyclin Pcl5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-06   28.3   0.0      2e-06   28.3   0.0    2.6  4  Cyclin    Cyclin
    0.00035   20.3   0.0    0.00083   19.1   0.0    1.7  1  Cyclin_N  Cyclin, N-terminal domain


Domain annotation for each model (and alignments):
>> Cyclin  Cyclin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.3   1.3         2   1.8e+04      31      58 ..      28      55 ..      13      65 .. 0.39
   2 !   28.3   0.0   2.2e-10     2e-06     112     161 .]     239     288 ..     197     288 .. 0.93
   3 ?   -1.9   0.0      0.41   3.7e+03      58      79 ..     419     440 ..     362     447 .. 0.75
   4 ?   -3.4   1.0       1.2   1.1e+04      22      40 ..     488     506 ..     473     538 .. 0.50

  Alignments for each domain:
  == domain 1  score: -4.3 bits;  conditional E-value: 2
                ---T.....................T-- CS
      Cyclin 31 nlensqkqssshtkttfaqtpkessFat 58
                 +  s   sss+   +++  + +ss ++
  EEA22733.1 28 SSVGSSASSSSSSIFSLDCVSTQSSISS 55
                3333333333333333333333333333 PP

  == domain 2  score: 28.3 bits;  conditional E-value: 2.2e-10
                 HHHHHHHHHHHHHH-SS---HHHHHHHHTS-HHHHHHHHHHHHHHTTT-- CS
      Cyclin 112 RllivallvatKflvDlsysnekfakvggislkELnkLEidFlflvdFdl 161
                 R+ ++al  a+K l+D  ys   ++k+ g++ +E+n+ E+ Fl  vd++l
  EEA22733.1 239 RMFLAALILASKYLQDRNYSARAWSKISGLQTQEINQNEMMFLQAVDWKL 288
                 999********************************************986 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 0.41
                 -SS--SS-HHHHHHHHHHHTT- CS
      Cyclin  58 tkavpaisigsylsrlqkfges 79 
                 +   pa+s++  +sr  +f+++
  EEA22733.1 419 AASTPAVSVRGTCSRRPSFASA 440
                 4456999999999999888875 PP

  == domain 4  score: -3.4 bits;  conditional E-value: 1.2
                 ------------T...... CS
      Cyclin  22 atasadsksnlensqkqss 40 
                     +d++  +++s + ss
  EEA22733.1 488 ESMVSDVSTISSRSSRSSS 506
                 3333333333333333333 PP

>> Cyclin_N  Cyclin, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   9.3e-08   0.00083      75     126 ..     239     288 ..     214     289 .. 0.94

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 9.3e-08
                 HHHHHHHHHHHHHHSSS---HHHHHHHTTTSS-HHHHHHHHHHHHHHTTT-- CS
    Cyclin_N  75 lvgatcLllAaKveeisppkledlvyitdeafteeeilemErliLetLnfdl 126
                 ++++++L+lA+K+ +++  +++ +  i++   + +ei++ E+ +L++ +++l
  EEA22733.1 239 RMFLAALILASKYLQDRNYSARAWSKISG--LQTQEINQNEMMFLQAVDWKL 288
                 7899*************99*****99976..999****************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (702 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       589  (0.0328518); expected 358.6 (0.02)
Passed bias filter:                      262  (0.0146132); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.76u 0.37s 00:00:01.12 Elapsed: 00:00:00.56
# Mc/sec: 3742.76
//
Query:       EEA22734.1  [L=1207]
Description: RNA-dependent RNA polymerase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   3.1e-182  607.3   0.0     4e-182  607.0   0.0    1.1  1  RdRP      RNA dependent RNA polymerase


Domain annotation for each model (and alignments):
>> RdRP  RNA dependent RNA polymerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  607.0   0.0  2.2e-186    4e-182       1     586 []     422    1024 ..     422    1024 .. 0.91

  Alignments for each domain:
  == domain 1  score: 607.0 bits;  conditional E-value: 2.2e-186
        RdRP    1 vtptriilegpeleksnrvlRrfkegsdrFlrvkfpdedge..rldse.dgeellkervkkvlkegiviagrkfeflafsdsqlrehsvwffapf.. 92  
                  vtpt ++l+gp++e  nrvlR+++++sd+F+rv+f +e+g+   +d   ++ + +++r+++vl++g+ ia+r+++fl+fs+s+lr++s+wf+a+f  
  EEA22734.1  422 VTPTGLYLDGPNVEAENRVLRKYRNQSDQFIRVRFIEESGDplMYD-IsSNLDPIFDRFREVLRDGVIIADRHYRFLGFSHSSLRSRSCWFMAEFhd 517 
                  79*************************************9974333.357788999************************************99975 PP

        RdRP   93 eeegerisaeeirkwlgdfenisqsvaKyaaRlglalSttrptvvkvereqiiieeidDv.kneekdiylftDGvGliSrelarkiakklglkkaee 188 
                  + +ge i++++++++lgdf++i + ++K+aaRlg+ +S+t ++ ++v+++   +++idDv +n+    ++f+DG+G+iS+e++ +i + +  + a+ 
  EEA22734.1  518 SVTGEFITVNKLISKLGDFDHI-KAPSKFAARLGQTFSDTLTS-ISVDKDM--VKRIDDVeRNG----RVFSDGCGTISKEILWRIYRDYPRN-AAV 605 
                  444444****************.*******************8.8888775..689***96766....89********************996.889 PP

        RdRP  189 lPsafQiRigGaKGvlavdkrlkpekielrpSqiKfkseeddsekrtleivkvsskpkpayLnrqlikiLedlgvpeevflellkealeelrealkd 285 
                  +P++fQ+Ri GaKG+l++d++lk  +i+lr+S+iKf++e+   + +++ei+    ++ p+yLn +likiLedlgvp++ flel++e++e+lr++ ++
  EEA22734.1  606 RPTVFQVRISGAKGMLSLDPTLKGPTICLRDSMIKFRAEA---D-NNIEICGSGIHSLPCYLNAPLIKILEDLGVPRDLFLELQREEVESLRQTVRS 698 
                  **********************4467**********7774...3.67************************************************** PP

        RdRP  286 agaaaell.kka.gdpskleellaelldsgfdpseldpflrsllkalvkeslrklkekarIpvpksatllgvaDetgvLkegevfvqlsealdqede 380 
                   ++aa +l +++ +++++l++l+  l ++g++ + +d fl++ ++ ++  +lr+lk+karI vp+++tl+g++Detg+Lkege+fv + +     ++
  EEA22734.1  699 PQHAAVFLdQAHiSKSTRLSWLITLLQSMGVNYN-QDGFLKRAVELVILMKLRDLKYKARILVPDGVTLYGIMDETGYLKEGEIFVPILNE----ET 790 
                  ********6555688****************887.56************************************************888543....34 PP

        RdRP  381 ksktkllkgdvlVtRnPalhpgDiqvvkavdvp...elrhlkdviVFstkGdrslaselsGGDlDGDkywViwdpelefapakpsneepadyeea.k 473 
                  k+++ l+++dvl+tR+Pa hpgD+q ++av+vp   +lr+l++++VFs+kG+r+l+s+lsGGDlDGD++++i+dp+++     ++ ++pady+ + +
  EEA22734.1  791 KRRDILVQDDVLITRSPAFHPGDVQLANAVNVPedsPLRKLHNCVVFSQKGTRDLPSQLSGGDLDGDIFNIIYDPRFR----LRRLAKPADYP-RvP 882 
                  4457888888********************998899****************************************97....356688*****.889 PP

        RdRP  474 pkeldrevtvediadffveymksdvlGlisnahlaiadq.eegiddpkclkLaelhskaVDypKtGipvdkkeiprelkkpkekPdf.......... 559 
                   +el+r+v+++di+dffv++m++d+lG+i++ h+++adq  +g++dp+cl La+lhs+aVD++KtG+pvd k ipr +    ++Pdf          
  EEA22734.1  883 GTELGRPVQIDDIQDFFVTFMQQDQLGRIATTHKILADQqVKGTFDPNCLTLAQLHSTAVDFSKTGTPVDIKMIPRYP---PYRPDFmapgprvrva 976 
                  9*********************************************************************88888876...579***9999999999 PP

        RdRP  560 ......................kekekkekakkpyykskkilgkLyrev 586 
                                        ++++ + ++  +yyks+++lg Lyr++
  EEA22734.1  977 esievldngdeyiwnndsesviDDDD-DVRPPMRYYKSRRVLGALYRMI 1024
                  99999999988888877776653222.3456899*************86 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1207 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       389  (0.0216967); expected 358.6 (0.02)
Passed bias filter:                      368  (0.0205254); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.94u 0.35s 00:00:01.29 Elapsed: 00:00:00.57
# Mc/sec: 6344.60
//
Query:       EEA22735.1  [L=636]
Description: hypothetical protein PMAA_093510 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      0.009   15.4   8.2      0.027   13.8   2.2    2.5  2  CorA      CorA-like Mg2+ transporter protein


Domain annotation for each model (and alignments):
>> CorA  CorA-like Mg2+ transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.4   0.6    0.0011        20     148     223 ..     390     473 ..     380     494 .. 0.73
   2 !   13.8   2.2   1.5e-06     0.027     228     255 ..     534     561 ..     478     608 .. 0.76

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.0011
        CorA 148 eilrelaqlrrrlvklrralapnrevlkrlla........kaddkllddedkeylrdlldelerllemlealrerleslqdtys 223
                 ++l++l++++ +l ++  +++ n +vl ++++          +  +++d  +   +d  ++++ ++++l+  + r++sl +  s
  EEA22735.1 390 DQLQDLSRIESTLQEISLVMKLNADVLLEIMEyyqrliddPYFPIEIKDGSSTAVSDFFQQIRIIINELKREQCRIDSLLQVVS 473
                 899*************99999999999966664444444655666666666666666666666666666666666666666555 PP

  == domain 2  score: 13.8 bits;  conditional E-value: 1.5e-06
        CorA 228 erlNrvmkvLTvltaiflPlTlitGiyG 255
                 er    m ++T++t iflP T+i++++G
  EEA22735.1 534 ERETASMHIITLVTLIFLPGTFIATFLG 561
                 34445799*******************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (636 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       945  (0.0527079); expected 358.6 (0.02)
Passed bias filter:                      664  (0.037035); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.86u 0.38s 00:00:01.24 Elapsed: 00:00:00.70
# Mc/sec: 2736.43
//
Query:       EEA22736.1  [L=862]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.6e-19   70.4   0.1    4.5e-19   68.9   0.0    1.7  2  Pkinase      Protein kinase domain
    2.3e-15   56.6   0.0    4.1e-15   55.8   0.0    1.3  1  Pkinase_Tyr  Protein tyrosine kinase


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.9   0.0     5e-23   4.5e-19      21     191 ..     182     387 ..     175     414 .. 0.83
   2 ?   -2.4   0.0      0.28   2.5e+03     204     248 ..     756     823 ..     743     826 .. 0.62

  Alignments for each domain:
  == domain 1  score: 68.9 bits;  conditional E-value: 5e-23
                 TTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHS....CTTB--EEEEEEESSEEEEEEE--TTEBHHHHHHHHSS.--HHHHH...HHHHHHHHHH CS
     Pkinase  21 ketgkivAvKkikkekakkkkekkvlrEikilkklk....hpnivrlyevfeekdelylvleyveggeladllerkgs.lseeeak...kiakqilegl 111
                 +++++ v++K+  k++++++ ++++ + ++++   +    +++ +++y++f+++++ +++ley+++g+l ++ + +++  + ee+    + ++ +l gl
  EEA22736.1 182 QTKEDLVVIKEYPKSEIEHSFKNELKAYMSFHYAGDepyvSKYFLKYYGSFKQNNKGFIILEYADEGSLLEFFKSNQVpRTREELHglfENLSDLLYGL 280
                 567889999****9999999987666666666666644556677899*********************99999954444777777722244567899** PP

                 HHHHHTT.........EE-SS-SGGGEEEETTTE.......EEE-SGTTSEESSSSCS...BCTTTSCGGGS-HHHH........TTSCBSHHHHHHHH CS
     Pkinase 112 eylHskg.........iiHrDlKpeNiLidekge.......lKitDFGlakelesssk...ltsfvgtseYlAPEvl........keneyskkvDvWsl 183
                 + lH+k           +H DlKp+Ni+++++++       +Ki+DFGl +   ++ +    ++  g   Y APE+          ++++s+ vD+Ws 
  EEA22736.1 281 RILHAKDlgktnrqlrGVHQDLKPANIFVSRNENggtyqynFKIGDFGLTSFTPTEANeikNRDNKGGIMYNAPEMTnyddfsrsLDEGISHLVDIWSF 379
                 ****9987788888888*************76667889999**********9999888888999*************8877765444899********* PP

                 HHHHHHHH CS
     Pkinase 184 Gvilyell 191
                  ++l+e  
  EEA22736.1 380 SCVLFEAA 387
                 *****974 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.28
                 HHHHHHHHTHHHHHHHCTSHH...HHHTTS.......................-HHHHHHHHHHT-SS CS
     Pkinase 204 ekvekeldqlekilkilgetkeklpeasei.......................seeakdllkkllkkd 248
                 ++ e+++    +i kil+++kek+ ++++                        ++ +++l++++++ +
  EEA22736.1 756 KQEEAICYMQSSIGKILNQVKEKISHKNSEtsiyiltdgiwddaidsrnicgvDNAILSLVREMCRLN 823
                 22233333336788888877777776665556677777777777777777777777777777777665 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.8   0.0   4.6e-19   4.1e-15      24     200 ..     181     388 ..     163     418 .. 0.75

  Alignments for each domain:
  == domain 1  score: 55.8 bits;  conditional E-value: 4.6e-19
                  TTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS....-BTTB....--EEEEEESSSSEEEEEE--TTEBHHHHHHHT..CTTTSBHHHHHHHHHH CS
  Pkinase_Tyr  24 kekkevkVavKtlkeeateeekeelleeakimkkl....khpni....vkllgvctkeepllivteyvkgGdLlkfLrkk..ekekltlkdllsfalq 111
                   ++ke  V++K   ++  e+   ++ +e+k  +++    + p +    +k++g   ++++ +i++ey+++G+Ll+f +++   +++ +l+ l++   +
   EEA22736.1 181 LQTKEDLVVIKEYPKSEIEH---SFKNELKAYMSFhyagDEPYVskyfLKYYGSFKQNNKGFIILEYADEGSLLEFFKSNqvPRTREELHGLFENLSD 275
                  45566678888874444443...344444333332101244444222278999999***********************9332334455667777888 PP

                  HHHHHHHHHHTTE.........EEST-SGGGEEEEE.......TTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSE........EEHH CS
  Pkinase_Tyr 112 vAkGmeyLeskkl.........vHrdlaarNvLlse.......nkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekk........ftsk 185
                  +  G++ L++k+l         vH+dl   N+++s+       +   ki+DfGL++ + ++ +  k++++k  + + apE+ ++          +++ 
   EEA22736.1 276 LLYGLRILHAKDLgktnrqlrgVHQDLKPANIFVSRnenggtyQYNFKIGDFGLTSFTPTEANEIKNRDNKGGIMYNAPEMTNYDDfsrsldegISHL 373
                  889*****99874444444455*************99999998889************999999*******************999888888889999 PP

                  HHHHHHHHHHHHHHT CS
  Pkinase_Tyr 186 sDvWsfGvllwEift 200
                   D+Wsf+ +l+E + 
   EEA22736.1 374 VDIWSFSCVLFEAAV 388
                  ************875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (862 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       443  (0.0247086); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.83u 0.34s 00:00:01.17 Elapsed: 00:00:00.56
# Mc/sec: 4618.30
//
Query:       EEA22737.1  [L=251]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (251 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       361  (0.020135); expected 358.6 (0.02)
Passed bias filter:                      330  (0.0184059); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.44
# Mc/sec: 1721.04
//
Query:       EEA22738.1  [L=595]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
   8.2e-110  368.4  44.6   2.9e-108  363.3  44.6    2.0  1  Drc1-Sld2  DNA replication and checkpoint protein


Domain annotation for each model (and alignments):
>> Drc1-Sld2  DNA replication and checkpoint protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  363.3  44.6  1.6e-112  2.9e-108       2     450 .]      17     595 .]      16     595 .] 0.79

  Alignments for each domain:
  == domain 1  score: 363.3 bits;  conditional E-value: 1.6e-112
   Drc1-Sld2   2 sqLraelKeWEraFaakn.grkpsreDIKknpeIaakYkeYskLkake.......sqskkdkkpsksvkleerpkkrkhesteepkeeqknnststprk 92 
                 ++Lr elK+WE+aFa++n grk++r DIK++p IaakYk+Y +L+a e        + ++dk+psk+++ e+r+k ++ +  ++++e+   n+  tprk
  EEA22738.1  17 NTLRVELKQWEKAFADANgGRKAGRHDIKQDPSIAAKYKTYGRLRALEesststhHAGGQDKTPSKPSNRETRTKRKHADIAHDDTET---NNHYTPRK 112
                 79********************************************997543322234577889999999888888888888777555...8999**** PP

   Drc1-Sld2  93 skkaiaaTPsk.....shpsevdpydsPsvlrrlfsPst............kaalGPTPQrdGkvLgLFDllsespksspskskerkaslsgsavqtps 174
                   ++ + TPsk     +hp+ +dpydsPsv rrlfsPst            k+++GPTPQr+Gk+LgLFD+ls+s+++++++s++r a l  ++vqtps
  EEA22738.1 113 ARRE-IITPSKnninpNHPATLDPYDSPSVFRRLFSPSThrqsqqpsplpfKTSIGPTPQRNGKILGLFDMLSASGGNTATPSAKRVAALDHAIVQTPS 210
                 **96.9********************************************************************************************* PP

   Drc1-Sld2 175 krr.aldinaeed....................rtpassgkklllsslfatpttlr........eaesakn......kkdkeasknsssskleseTPsf 238
                 +r+  +++ + ++                    rtpass k+l+l+ lfatpttlr        +++   +      +k  ++++ ++++ l s TPsf
  EEA22738.1 211 RRKtGQKLDNISEsadnegdkedneyentigmgRTPASSSKRLYLERLFATPTTLRfatmmeneKDN---QpqrilyQKAVTEAQTDEKDALASGTPSF 306
                 **964444333334578***************************************88888554333...2334666666666666677777******* PP

   Drc1-Sld2 239 lrrknsarlptvdease.fdlspsplrkpqrlvgkglsaivqelrdieeeklddeldllremEaeeeqaeldd..vedsqa......seaeegrvrkkk 328
                 lrr+ns r+  ++ +++  +lsp+ +rk qr  gkgl+a+vq+lrd+e+e++dd++d+l+e+Eae+++++ ++  v dsq+      + ++ grv+kkk
  EEA22738.1 307 LRRSNSGRYVSSNDNDSaNPLSPVGVRKHQRYNGKGLTALVQGLRDMENERMDDDWDILNEIEAEQNGTAGENvqVGDSQVphdatgEDPNGGRVWKKK 405
                 *****99988887777779**********************************************9998877767889999666666666666****** PP

   Drc1-Sld2 329 gqkrttRrvkmkPvt.........................eeeeededekknsedeldklpetqrkae...klddel.seredseededsdsdeesese 398
                 gqkrttR vkmkPv+                         +ee+ede++ k  + + d lp t+   e    ++d+l ++++++eed+ +d d++++s+
  EEA22738.1 406 GQKRTTRLVKMKPVMqvknkpsrtttanasksteqrqdeeSEESEDELQPKSPGADEDSLPRTRTLRErkqTTEDNLnEDDANEEEDDYNDIDSDNNSD 504
                 ***********************9999888766666555544444455555555555555555443336655555553222222222222222222222 PP

   Drc1-Sld2 399 ptakaksfke.kakk..kkkakkkkvkkvst............................................NyrrLKirnkgakgra.kgRfrrR 449
                  +     f+e + +k   + ++ k                                                   Nyr+LKir+kg  gr   gRf +R
  EEA22738.1 505 DLD----FTEtASAKqaLPTTMVKPMS---SfseklkaafssvkplkkkavaekdedkpkpsspkkrkvnpdahaNYRSLKIRSKGQ-GRFgRGRF-GR 594
                 222....22211111121122222222...23335555667888888899999999999999999999999999***********65.88889***.55 PP

   Drc1-Sld2 450 R 450
                 R
  EEA22738.1 595 R 595
                 5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (595 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1336  (0.0745161); expected 358.6 (0.02)
Passed bias filter:                      353  (0.0196888); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.74u 0.31s 00:00:01.05 Elapsed: 00:00:00.47
# Mc/sec: 3797.83
//
Query:       EEA22739.1  [L=823]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-11   44.3   0.1    2.1e-11   43.4   0.1    1.4  1  Fungal_trans  Fungal specific transcription factor domain
    1.1e-09   38.3   7.8    1.8e-09   37.6   7.8    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.4   0.1   2.4e-15   2.1e-11      13     203 ..     320     511 ..     308     551 .. 0.74

  Alignments for each domain:
  == domain 1  score: 43.4 bits;  conditional E-value: 2.4e-15
  Fungal_trans  13 pilhkpsflpkt...ssenssksayasplll..lailalGalfsesetkesnssltses.qefiafplraeili.hedfsspssslwilqsLlllel 102
                    ++h psf ++    + + +++  ++ ++++  l++la +  f e e   + +++  ++ ++ + +   ae++   +  + p+  +  +q+Ll+++ 
    EEA22739.1 320 RVIHIPSFRRELaemHANIHNPDMISAAFVVqlLLMLAAAVGFYEAEPPLEYADSNISKtFQVVDWIRYAEKWMdTTYVKRPDMTTLRIQCLLIIAK 416
                   678999999999998444444444444444444999999999999888888777766666444444445555553335556666677888******* PP

  Fungal_trans 103 yektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddlwesddas 199
                    ++++  r+++++  g  v++a   g hr+p++       k + +++e+rrR+w ++  lD +ia++ G pp+l +s+ +++ P + +d ++++ ++
    EEA22739.1 417 NNQGLK-RSQAWLATGNLVKMAMLAGYHRDPANIP-----KITLFNKEMRRRMWATIIELDAQIAIDRGMPPTLQASDFDTASPLNINDDEIHEGTT 507
                   999999.6*************************98.....599999**************************7777777777666666555544444 PP

  Fungal_trans 200 eetl 203
                   ee +
    EEA22739.1 508 EEPQ 511
                   4333 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.6   7.8     2e-13   1.8e-09       2      36 ..      36      71 ..      35      75 .. 0.92

  Alignments for each domain:
  == domain 1  score: 37.6 bits;  conditional E-value: 2e-13
                S-HHHHHCT---STSSSS-HHHHHCT..HHHCCCCTC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkkln..leCtfyses 36
                aC++Cr +K KCd++ PaCs+C k++    C+ y++s
  EEA22739.1 36 ACTQCRTRKLKCDREYPACSRCLKSGipDRCK-YEDS 71
                9*************************9999*9.8876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (823 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       581  (0.0324056); expected 358.6 (0.02)
Passed bias filter:                      455  (0.0253779); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.66u 0.34s 00:00:01.00 Elapsed: 00:00:00.48
# Mc/sec: 5117.46
//
Query:       EEA22740.1  [L=296]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.8e-67  227.0   0.0    2.2e-67  226.8   0.0    1.0  1  Suc_Fer-like  Sucrase/ferredoxin-like


Domain annotation for each model (and alignments):
>> Suc_Fer-like  Sucrase/ferredoxin-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  226.8   0.0   1.2e-71   2.2e-67       1     195 []      53     285 ..      53     285 .. 0.95

  Alignments for each domain:
  == domain 1  score: 226.8 bits;  conditional E-value: 1.2e-71
  Suc_Fer-like   1 llgtvkayskhvlvatgksdWpskvedekgslaealkklk....lllsasslp.........eekseeekttvlllPdfklveevtpssveelvkef 84 
                   ++g++k++++hvlvat+ksdW+sk e e+g++++al +++    l+++as+l+         +++ +e+ ttvlllP+f+++++vt   v+elv++f
    EEA22740.1  53 IYGKIKPFATHVLVATSKSDWVSKPEWERGTIVHALCEANskerLMVNASNLTapedksstsSADGKENATTVLLLPSFQFIDNVTVPYVPELVSRF 149
                   589*********************99999*******9984599****************99866778999*************************** PP

  Suc_Fer-like  85 lkp..................kvrklpekaliLvCshktrDarCgilapllrkelerelre......kederpggvrvgfisHvGGHkfAgnviiyr 157
                   +++                  k r++p+++++L+Cshk+rDarCgi+apl++keler+lr+       +derpgg++++f+sHvGGHkf++nv++yr
    EEA22740.1 150 IDNddsntsltpteissssslKPRPCPHDYVVLLCSHKRRDARCGISAPLIKKELERHLRPaglyrdANDERPGGAGIYFVSHVGGHKFSANVLVYR 246
                   **8899***************99**************************************88887777**************************** PP

  Suc_Fer-like 158 kekagqgiwygrvepedvegiveetilkgkvvke..llRg 195
                   ++ ++q+iw++r++pe++egiv++til+gkvv++  +lRg
    EEA22740.1 247 RQ-EEQLIWLARIRPEHCEGIVKYTILQGKVVHPevQLRG 285
                   *9.6****************************99888997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (296 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       409  (0.0228122); expected 358.6 (0.02)
Passed bias filter:                      352  (0.019633); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.46
# Mc/sec: 1924.27
//
Query:       EEA22741.1  [L=163]
Description: non-classical export protein Nce102, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-23   83.5   6.1    1.8e-23   83.1   6.1    1.0  1  MARVEL    Membrane-associating domain


Domain annotation for each model (and alignments):
>> MARVEL  Membrane-associating domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.1   6.1     1e-27   1.8e-23       7     143 ..       7     138 ..       3     138 .. 0.91

  Alignments for each domain:
  == domain 1  score: 83.1 bits;  conditional E-value: 1e-27
      MARVEL   7 gilrilqlvfaiiilgliasliakldqllgspssalnfavfvavfsflyalfllvlylfknsaftsilwplidlivdalaallwlvafialaaglrdis 105
                 + lr +++ f++i lgli+sl        g ++ ++ +++f++++s ++ ++l+ +++    +     +p+i +ivda +++++++a+i+laa + + +
  EEA22741.1   7 LGLRAFEFSFTVILLGLIGSLE-----TSGGNPESVHYSMFTSAWSAFFLIYLIPATA----TESLVGHPIIPVIVDATNVVFTFCAAITLAARTMGRN 96 
                 689*******************.....79********************999999966....445578******************************* PP

      MARVEL 106 cafe....snqysasltvrcgqaqaavafgflavllfaasav 143
                 c+++     n+    +  rc++aqa++af ++ +++++as++
  EEA22741.1  97 CSNHdftdHNEIAMGSENRCREAQASCAFFWFLWVCYVASMI 138
                 **555557788999999***********************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (163 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       608  (0.0339115); expected 358.6 (0.02)
Passed bias filter:                      366  (0.0204139); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.25s 00:00:00.67 Elapsed: 00:00:00.40
# Mc/sec: 1218.74
//
Query:       EEA22742.1  [L=691]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (691 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       797  (0.0444531); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.43
# Mc/sec: 4821.65
//
Query:       EEA22743.1  [L=768]
Description: alpha-N-acetylglucosaminidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   5.3e-136  453.0   5.6     7e-136  452.5   5.6    1.2  1  NAGLU     Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel do
    6.5e-73  245.5   3.7    9.9e-73  244.9   3.7    1.2  1  NAGLU_C   Alpha-N-acetylglucosaminidase (NAGLU) C-terminal do
    1.3e-20   72.9   0.0    3.3e-20   71.6   0.0    1.7  1  NAGLU_N   Alpha-N-acetylglucosaminidase (NAGLU) N-terminal do
  ------ inclusion threshold ------
      0.049   13.9   1.6       0.12   12.7   1.6    1.6  1  DUF3446   Early growth response N-terminal domain


Domain annotation for each model (and alignments):
>> NAGLU  Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  452.5   5.6  1.6e-139    7e-136       1     332 [.     136     473 ..     136     474 .. 0.99

  Alignments for each domain:
  == domain 1  score: 452.5 bits;  conditional E-value: 1.6e-139
                 EEE--TTHHHHTTTT--HHHHHHHHHHHHHTT--EEE--TTHHHHHHHHHGGGT--HHHHHHHS--TT-HHHHHTTS--S.TT----TTHHHHHHHHHH CS
       NAGLU   1 RyylNvctfsYtmafwdwerWereiDwmAlnGinlpLaivGqeavwqevlkelglsdeeikeflsgpaflawqrmgnleg.wggplpqswiekqaeLqk 98 
                 Ry++N++t+sYt afw+we+We ++DwmAl+G+nlpLa++G e+++ ev++elgl+d+ei++flsgpaflaw+++gn++g wg+plp +w+++q++Lqk
  EEA22743.1 136 RYHFNTVTTSYTSAFWSWEDWELQLDWMALRGVNLPLAWIGVEKIFIEVFQELGLTDAEISDFLSGPAFLAWNHFGNIQGsWGSPLPYAWVDSQFDLQK 234
                 9*******************************************************************************9****************** PP

                 HHHHHHHHHT-EEEEE--S-EE-TTHHHHSTT--EE---EETT....EE--EEE-SS--HHHHHHHHHHHHHHHHH-.--SEEE--TTTTS-..--TT- CS
       NAGLU  99 kilkrmrelgmtpvlpaFaGhvPkalkeklpkakvteqgewsg....fkrpafldptdplfakiakafleeqkklyg.tshiYaaDpFnEgepkssdee 192
                 ki+krm elgmtp+lpaF G+vP+a++++lp+a+v++ + w+     f++++f++ptdp+f++i+k+f+++q+++yg ++++Y++D+FnE++p+s d +
  EEA22743.1 235 KIVKRMVELGMTPILPAFPGFVPRAITRVLPDADVINGSAWEAfpamFTSDTFMEPTDPHFTEIQKSFISKQTAAYGnVTTFYTLDQFNENNPSSGDLN 333
                 ******************************************99999******************************99******************** PP

                 -HHHHHHHHHHHHHHH-TT-EEEEEEBTT.........BS-HHHHTT-S.GGGEEEEETTTTTS-......HTTT--EEEEE---STT--SS---HHHH CS
       NAGLU 193 ylaavskaiykalkaadpkavWvlqgWlfvsdkkfWtkerveallsavp.kdklliLDlfsekkpvwkrtksfegkpwiwcmlhnfGgrtglyGklekv 290
                 yl++vs+ +++alkaadp+avWv+qgWlf+s+++fWt++rvea+l +v+ +++ll+LDl+se++p+w+rt+s++gkpwiwc++h++Gg++g+yG++ ++
  EEA22743.1 334 YLRSVSHGTWQALKAADPSAVWVMQGWLFFSNSAFWTNDRVEAYLGGVTvDSDLLVLDLASESQPQWQRTNSYFGKPWIWCQIHDYGGNMGFYGQVMNI 432
                 *************************************************999*********************************************** PP

                 HHHHHHHHHT-S...EEEEEE--S-S-S-HHHHHHHHHGGG- CS
       NAGLU 291 aseiaealakkeksklvGiGltpEgiennpvvyelllelaws 332
                 + ++++al ++++ +lvG+Gl +Eg+e n+vvy+lll++aws
  EEA22743.1 433 TVNPIAAL-NNATASLVGFGLSMEGQEGNEVVYDLLLDQAWS 473
                 ********.55778***************************8 PP

>> NAGLU_C  Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  244.9   3.7   2.2e-76   9.9e-73       1     251 [.     482     739 ..     482     749 .. 0.92

  Alignments for each domain:
  == domain 1  score: 244.9 bits;  conditional E-value: 2.2e-76
                 HHHHHHHHHHT...---HHHHHHHHHHHHTTTS---S---SS---GGGS-S-SS---SSTT..-----S-HHHHHHHHHHHHHHHHH...HTT-HHHHH CS
     NAGLU_C   1 WvkdYakrRyg...kedeeleeAweiLletvYnntkkeaegapesliearPslnakkassk..kaekkYdpkdllkawkllleaade...lkssetyry 91 
                 +++d++++Ry    + ++++++Aw++L+++vYnnt+  ++++p++++e+ Ps++   +++   +++ +Y+p+d++kaw+l+++aa +   l+ +++y++
  EEA22743.1 482 YFHDWVTARYAgskSIPTDVYSAWDMLRTSVYNNTNLASNAVPKAIFELIPSTTGLVNRTGhhPTTLNYNPADMVKAWSLFYSAAFKepsLWLNPAYEF 580
                 89********99988899***********************************977666554566667****************988899********* PP

                 HHHHHHHHHHHHHHHHHHHHHHHHHHTT-HH..HHHHHHHHHHHHHHHHHHHHTT-GGGBHHHHHHHHHHSSTT--HHHHHHHHHHHHTTTSSTT.TS- CS
     NAGLU_C  92 Dlvdvtrqvlanlakelykelvaaykakdae..afkkaskkllelledlDellatreeflLgkWiedArslakteeekelyelnArnqiTlWggpegel 188
                 Dlvd++rqvlan++ ++y++l+aa+++ + +  +++  +++l+ +l+ +D++l t+e+f+L++Wi++Ar  a +++ ++++e+nA nqiTlW gp+g++
  EEA22743.1 581 DLVDMSRQVLANAFIPVYHDLIAAWNTTNPStiRIQIIGAELIGILQAIDTILDTNEHFKLSTWISAARTSAGEQSLEDFLEYNALNQITLW-GPTGQI 678
                 ****************************77722566779***********************************999***************.689*** PP

                 TTTT----BTHHHHTHHHHHHHHHHHHHHHHTT-S---.......HHHHHHHHHT--T----S CS
     NAGLU_C 189 nDYAnkeWsGLvkdYYlpRWklFvdalaealeegkefdeeelkkklfefeeaWveskkeypsk 251
                 +DYA+k+W+GLv++YY pRWk+F+++l+++  +  +++++++k++l ++e++W++++ +  +k
  EEA22743.1 679 SDYASKSWAGLVSSYYIPRWKMFIEYLVDT--KPAQYNQTAFKAELLKWELQWQNDTIAAATK 739
                 ***************************998..888899***************9998766665 PP

>> NAGLU_N  Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.6   0.0   7.5e-24   3.3e-20       2      81 ..      36     121 ..      35     122 .. 0.91

  Alignments for each domain:
  == domain 1  score: 71.6 bits;  conditional E-value: 7.5e-24
                 HHHHHHHHHH-GGGGGEEEEE...--BTTB-EEEEE-SSS.-EEEEESSHHHHHHHHHHHHHHHS--B--T.T--B--.--.SS-- CS
     NAGLU_N   2 avrelleRllpehaskfkfelv..eeksgkdvFeisskgg.kilIrGnsgvalasGlnwYLkyycgvhisw.ngdqlk.lP.avLP 81 
                 ++++ll+R+lp+ha+kf+f++v  ++ +++d +++ ++++ +i ++G+s +ala+Gl++YL ++++v+i+w  g++l+ +   +LP
  EEA22743.1  36 GIESLLQRRLPQHAHKFEFSVVnaTSLGENDAYTVANAENgRIKVEGSSLSALATGLHRYLADVAHVDIYWfIGSRLDqISaGQLP 121
                 6899******************865599********98888***********************************9986624577 PP

>> DUF3446  Early growth response N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   1.6   2.6e-05      0.12      20      52 ..       3      35 ..       1      61 [. 0.70

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.6e-05
     DUF3446 20 llslvsglvgvanppsspsssssssssssssss 52
                +l+l+sg++ +a+++ +++ s+s+s+ss+ s++
  EEA22743.1  3 ILNLISGVLAIASTAIAAPGSTSTSTSSQLSTT 35
                9**********8655544444444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (768 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       367  (0.0204696); expected 358.6 (0.02)
Passed bias filter:                      293  (0.0163422); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.66u 0.26s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 5119.01
//
Query:       EEA22744.1  [L=402]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    6.4e-12   45.6   1.0    6.4e-12   45.6   1.0    2.2  2  His_Phos_1  Histidine phosphatase superfamily (branch 1)


Domain annotation for each model (and alignments):
>> His_Phos_1  Histidine phosphatase superfamily (branch 1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.2      0.41   7.4e+03      85     102 ..     111     128 ..     109     145 .. 0.44
   2 !   45.6   1.0   3.6e-16   6.4e-12       2     157 ..     152     340 ..     151     352 .. 0.78

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 0.41
                 GTT-B.HHHHHH..HSHH CS
  His_Phos_1  85 weglttaeiaeeypeele 102
                 +eg++++ +a+e+p +  
  EEA22744.1 111 YEGQEHRAEADERPTTQW 128
                 555544444443332221 PP

  == domain 2  score: 45.6 bits;  conditional E-value: 3.6e-16
                 EEEE---BTT.....................B--....TT----B-HHHHHHHHHHHHHHTTS---EE......EE-SSHHHHHHHHHHHHCTT....- CS
  His_Phos_1   2 yLvRHGetew.....................naegrlqgrtdvpLteeGreqAealaerlagepidai......ysSplkRarqTaeliaealg....l 69 
                 yL RHGe  +                     n+    + ++d+ Lt+ Gr+qA+ + ++ +++  +ai      y+Spl R+ +Ta +  + l      
  EEA22744.1 152 YLGRHGEGFHnvaqswygddawdcywslqdgNE---TSTWSDARLTQVGRAQAQTAHDAWRKQIETAIpfpemfYVSPLNRCLETAFITFDGLVgrrpF 247
                 677777776666666677777777776533333...589********************99966666677788*************9999988778889 PP

                 -EEE-GGGS----G..GGTT-B.HH.HHHH..HSHHHHHHHHH-GGG-B..S-BHHHHHHHHHHHHHHHHHHTTTSE.EEEEE-HHHHHHHHHH CS
  His_Phos_1  70 pveldegLrEidfG..dweglttae.iaeeypeeleawlrdpadvrppg..gEsledvaaRvaaaleelaarheget.vlvVsHggvirallar 157
                 +++++e  rE+ +G   ++ ++t++ i++eyp++  +    ++d+  +    Es  +  aR++ +l+++ +++++++ + v +H g+i ++l  
  EEA22744.1 248 RPTVKELVRET-LGihTCDRRSTKTvIQDEYPDYIIEEGFTEDDELWHAeqRESDSARNARIKTFLDDVFTANSDKQfISVTAHSGAITSILDV 340
                 999*******4.553466666555526778888776644444433333346**************************9***********99875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (402 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       737  (0.0411066); expected 358.6 (0.02)
Passed bias filter:                      624  (0.0348039); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 2651.84
//
Query:       EEA22745.1  [L=373]
Description: hypothetical protein PMAA_093610 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (373 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       774  (0.0431703); expected 358.6 (0.02)
Passed bias filter:                      351  (0.0195772); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.50u 0.25s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2637.43
//
Query:       EEA22746.1  [L=342]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.5e-29  100.7   0.0    9.1e-29   99.7   0.0    1.5  1  Ribosomal_L22  Ribosomal protein L22p/L17e


Domain annotation for each model (and alignments):
>> Ribosomal_L22  Ribosomal protein L22p/L17e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   99.7   0.0   5.1e-33   9.1e-29       2     103 .]     170     300 ..     169     300 .. 0.99

  Alignments for each domain:
  == domain 1  score: 99.7 bits;  conditional E-value: 5.1e-33
                    EEEEESS-HHHHHHHHHHHTTSBHHHHHHHHHT-SSTTHHHHHHHHHHHHHHHH..HT.............................-GGGEEEEE CS
  Ribosomal_L22   2 kgsnlrvsfkklrevarlIrgmkveeAlkyLkfskkkaakfvlklLknaeanaelkgl.............................dvdslvIee 68 
                    k++++++s+kkl+++ar+I+g++++eA+ +++fskkk+ak+vl++Lk a++ a+++++                             d++s++I+e
     EEA22746.1 170 KSHWFKTSVKKLTPLARQIAGKNIDEAILQMRFSKKKVAKDVLEHLKLAKNTAIVRHGmglgkadessnkiqpidvilkdgekhtitDPTSIYIAE 265
                    79********************************************************************************************** PP

                    EEEEEEEEEEEEEEESTTEEEEEEEEEEEEEEEEE CS
  Ribosomal_L22  69 iqvnkgpklkrrtyrArGrinpirkspchievvlk 103
                    ++vn+gp   ++++rArG+in +r +++ ++vvlk
     EEA22746.1 266 AWVNRGPFDTGYDHRARGKINLLRLPYTGLSVVLK 300
                    *********************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       651  (0.0363099); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2409.94
//
Query:       EEA22747.1  [L=300]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    6.4e-55  185.9  11.2    8.2e-55  185.5  11.2    1.1  1  DUF1640      Protein of unknown function (DUF1640)
  ------ inclusion threshold ------
        6.4    7.2  10.5       0.79   10.1   5.1    2.0  2  Uso1_p115_C  Uso1 / p115 like vesicle tethering protein, C te


Domain annotation for each model (and alignments):
>> DUF1640  Protein of unknown function (DUF1640)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  185.5  11.2   9.1e-59   8.2e-55       1     175 []     125     299 ..     125     299 .. 1.00

  Alignments for each domain:
  == domain 1  score: 185.5 bits;  conditional E-value: 9.1e-59
     DUF1640   1 fDThalvrrLeekGftkeqAeaimsaltevlneslekvakslvskselekseylqkaalselrkevqisersefaalrseteklqreleklkqkLreei 99 
                 fDT+++v+rL+ +Gf++eqA a+m++l++v++es++++++++v k++ e+++y+qk+++++lr+e+ +s+ +e+++ rs++e+l  +l k++++Lr+ei
  EEA22747.1 125 FDTLKFVQRLKMEGFSEEQAVAMMKVLNDVIQESIQNLTRTMVLKEDSERATYTQKVDFAKLRSELLNSDSTEAQLTRSSHERLAADLAKMNSRLRDEI 223
                 9************************************************************************************************** PP

     DUF1640 100 dklkadirldlnleKgrireelakleakiqelnnkidrevsalrteiEsvKldvikyliglvvgilavglavvRll 175
                 ++++a++rldlnleKgriree +++e +i+e++++i++ev+ lr  + +vK  ++++l+g+++g++a++++++Rll
  EEA22747.1 224 SRTQASVRLDLNLEKGRIREEANSQEMRIKETETRIEQEVAGLRERVQAVKQSTLQWLVGVCTGTAALIIGAWRLL 299
                 **************************************************************************96 PP

>> Uso1_p115_C  Uso1 / p115 like vesicle tethering protein, C terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   2.7      0.01        93       6      68 ..     172     230 ..     140     238 .. 0.56
   2 ?   10.1   5.1   8.8e-05      0.79       4      74 ..     203     276 ..     200     279 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.01
  Uso1_p115_C   6 leseaaslkdeneklkaelqslskalesleqkeakkaaesqakeleaenkklekeleklrael 68 
                  +e+ + ++k   +kl +el ++++   +l ++    + e  a +l ++n++l++e+  ++a +
   EEA22747.1 172 SERATYTQKVDFAKLRSELLNSDSTEAQLTRS----SHERLAADLAKMNSRLRDEISRTQASV 230
                  33333333333344444433333333333333....455556666666666666666666555 PP

  == domain 2  score: 10.1 bits;  conditional E-value: 8.8e-05
  Uso1_p115_C   4 seleseaaslkdeneklkaelqslskalesleqk...eakkaaesqakeleaenkklekeleklraelkeekek 74 
                  s+ e+ aa+l ++n++l +e++ ++ +++   +       ++a+sq+++++++  + e+e+  lr+++++ k++
   EEA22747.1 203 SSHERLAADLAKMNSRLRDEISRTQASVRLDLNLekgRIREEANSQEMRIKETETRIEQEVAGLRERVQAVKQS 276
                  567999999**********9999988887443333458999999999999999999999*********999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (300 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1542  (0.0860059); expected 358.6 (0.02)
Passed bias filter:                      549  (0.0306208); expected 358.6 (0.02)
Passed Vit filter:                        56  (0.00312343); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.24s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 2133.59
//
Query:       EEA22748.1  [L=409]
Description: endoplasmic reticulum DnaJ domain protein Erj5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.7e-11   42.6   0.2    2.9e-10   40.1   0.1    2.2  2  DnaJ      DnaJ domain


Domain annotation for each model (and alignments):
>> DnaJ  DnaJ domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.1   0.1   1.6e-14   2.9e-10       1      34 [.      44      77 ..      44      86 .. 0.91
   2 ?   -0.3   0.0      0.07   1.2e+03      37      63 .]     114     139 ..     107     139 .. 0.82

  Alignments for each domain:
  == domain 1  score: 40.1 bits;  conditional E-value: 1.6e-14
                HHHHHHTSSTTG-HHHHHHHHHHHHHHHSTTTSC CS
        DnaJ  1 dyYeiLgvskdasedeIkkaYrklalkyHPDknp 34
                ++Y++Lgv+++a++d+I kaYrk+++++HPDk +
  EEA22748.1 44 TFYDFLGVAPNANQDDINKAYRKKSKQLHPDKVK 77
                58*****************************974 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.07
                 HHHHHHHHHHHHHHHHHTSHHHHHHHH CS
        DnaJ  37 peaeekFkeineAyevLsdpekRkqYD 63 
                 +ea+e+  ++n+  ++L  p +R++YD
  EEA22748.1 114 KEATERSARLNTVANILRGP-SRERYD 139
                 589999999********986.577777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (409 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1144  (0.0638072); expected 358.6 (0.02)
Passed bias filter:                      641  (0.0357521); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.30s 00:00:00.86 Elapsed: 00:00:00.44
# Mc/sec: 2816.64
//
Query:       EEA22749.1  [L=640]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.7e-42  142.2   1.2    6.6e-08   32.9   0.0    6.5  7  Ank_4         Ankyrin repeats (many copies)
    8.8e-40  135.2   0.8    7.9e-12   45.6   0.0    4.5  4  Ank_2         Ankyrin repeats (3 copies)
    1.6e-22   79.2   0.7     0.0002   21.6   0.1    7.4  8  Ank_5         Ankyrin repeats (many copies)
    4.7e-22   77.4   1.0       0.07   13.6   0.0    8.2  8  Ank           Ankyrin repeat
    5.6e-18   63.2   0.0       0.48   11.2   0.0    8.0  8  Ank_3         Ankyrin repeat
    3.3e-06   26.6   0.0    8.2e-06   25.2   0.0    1.7  1  PNP_UDP_1     Phosphorylase superfamily
     0.0018   18.1   4.1         21    5.1   0.0    5.4  6  YajC          Preprotein translocase subunit
  ------ inclusion threshold ------
        2.2    8.4   9.2        6.2    6.9   0.0    4.5  6  Toprim_C_rpt  Topoisomerase C-terminal repeat


Domain annotation for each model (and alignments):
>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0       2.5   5.7e+03      35      47 ..     382     394 ..     377     401 .. 0.86
   2 !   29.4   0.0   3.8e-10   8.6e-07       4      55 .]     419     469 ..     416     469 .. 0.93
   3 !   27.4   0.0   1.6e-09   3.7e-06       5      54 ..     453     501 ..     449     501 .. 0.87
   4 !   25.6   0.0   5.9e-09   1.3e-05       4      55 .]     485     535 ..     482     535 .. 0.89
   5 !   29.8   0.0     3e-10   6.6e-07       4      55 .]     518     568 ..     515     568 .. 0.92
   6 !   32.9   0.0   2.9e-11   6.6e-08       4      55 .]     551     601 ..     548     601 .. 0.92
   7 !   30.4   0.0   1.9e-10   4.2e-07       4      54 ..     584     633 ..     581     634 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 2.5
       Ank_4  35 GetalhiAakrgn 47 
                 +++alh  a +g+
  EEA22749.1 382 QMNALHVSAFNGH 394
                 5789*****9997 PP

  == domain 2  score: 29.4 bits;  conditional E-value: 3.8e-10
       Ank_4   4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 aL +a   g++++v++Llekga++naq  ++  +al+ A   g++ei++ Ll
  EEA22749.1 419 ALQWASLRGHFKSVQRLLEKGAEVNAQ-GGRYGNALQAASFEGHIEIVQILL 469
                 7999***********************.777778***************997 PP

  == domain 3  score: 27.4 bits;  conditional E-value: 1.6e-09
       Ank_4   5 LhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54 
                 L +a  +g++e+v++Lle+ga++naq  ++  +al+ A + g+vei++ L
  EEA22749.1 453 LQAASFEGHIEIVQILLERGAEVNAQ-GGEYGNALQAASLEGHVEIVQRL 501
                 545555********************.777779**************965 PP

  == domain 4  score: 25.6 bits;  conditional E-value: 5.9e-09
       Ank_4   4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 aL +a  +g++e+v++L ekga++naq  ++  +al+ A ++g++ei++ Ll
  EEA22749.1 485 ALQAASLEGHVEIVQRLPEKGAEVNAQ-GGRYGNALQAASSGGHIEIVQKLL 535
                 6767777********************.777778***************997 PP

  == domain 5  score: 29.8 bits;  conditional E-value: 3e-10
       Ank_4   4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 aL +a + g++e+v+ Llekga++naq  ++  +al  A +rg+ve+++ Ll
  EEA22749.1 518 ALQAASSGGHIEIVQKLLEKGAEVNAQ-GGDYGNALLVASYRGHVEVVQRLL 568
                 6778888********************.888889***************997 PP

  == domain 6  score: 32.9 bits;  conditional E-value: 2.9e-11
       Ank_4   4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 aL  a + g++e+v++Lle+ga++naq  +   +al+ A ++g++ei++ Ll
  EEA22749.1 551 ALLVASYRGHVEVVQRLLERGAEVNAQ-GGFYGNALQAASSGGHIEIVQRLL 601
                 789999*********************.777778***************997 PP

  == domain 7  score: 30.4 bits;  conditional E-value: 1.9e-10
       Ank_4   4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54 
                 aL +a + g++e+v++Llekga++naq  ++  +al  A ++g+v++++ L
  EEA22749.1 584 ALQAASSGGHIEIVQRLLEKGAEVNAQ-GGDYGNALLAASSGGHVDVVQVL 633
                 6778888********************.888889***************98 PP

>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0   0.0   4.5e-09     1e-05      27      82 ..     383     445 ..     372     446 .. 0.84
   2 !   45.6   0.0   3.5e-15   7.9e-12       3      82 ..     454     544 ..     453     545 .. 0.85
   3 !   44.3   0.0     9e-15     2e-11       3      82 ..     487     577 ..     485     578 .. 0.85
   4 !   39.3   0.0   3.2e-13   7.3e-10       2      73 ..     553     634 ..     552     640 .] 0.84

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 4.5e-09
       Ank_2  27 ktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlekgadinlk 82 
                 ++aLh++a ng+  +++ L           d++g ++L++A+  gh++ v+ Llekga++n++
  EEA22749.1 383 MNALHVSAFNGHDVVISKLSTDgksvineRDSTGANALQWASLRGHFKSVQRLLEKGAEVNAQ 445
                 79*********9555788886445675566699*********99****************985 PP

  == domain 2  score: 45.6 bits;  conditional E-value: 3.5e-15
       Ank_2   3 lAakn.gnlelvklLl.egadpn.k..ngktaLhyAakngnleivklLleh...ad....ndgrtpLhyAarsghleivklLlekgadinlk 82 
                 +Aa++ g+ e+v++Ll  ga++n +  +  +aL++A  +g++eiv+ L e+   ++    ++g ++L++A++ gh+eiv+ Llekga++n++
  EEA22749.1 454 QAASFeGHIEIVQILLeRGAEVNaQggEYGNALQAASLEGHVEIVQRLPEKgaeVNaqggRYG-NALQAASSGGHIEIVQKLLEKGAEVNAQ 544
                 677765999********99**998467456********************8867556445555.6******88****************985 PP

  == domain 3  score: 44.3 bits;  conditional E-value: 9e-15
       Ank_2   3 lAak.ngnlelvklLl.egadpn.k...ngktaLhyAakngnleivklLleh...ad....ndgrtpLhyAarsghleivklLlekgadinlk 82 
                 +Aa+ +g+ e+v+ L  +ga++n +      +aL++A ++g++eiv+ Lle+   ++    ++g+ +L +A+  gh e+v+ Lle+ga++n++
  EEA22749.1 487 QAASlEGHVEIVQRLPeKGAEVNaQggrY-GNALQAASSGGHIEIVQKLLEKgaeVNaqggDYGN-ALLVASYRGHVEVVQRLLERGAEVNAQ 577
                 45663799*******9999***9856745.5*******************988674455666675.******99****************985 PP

  == domain 4  score: 39.3 bits;  conditional E-value: 3.2e-13
       Ank_2   2 hlAakngnlelvklLl.egadpn.k..ngktaLhyAakngnleivklLleh...ad....ndgrtpLhyAarsghleivklLl 73 
                  +A++ g+ e+v+ Ll  ga++n +  +  +aL++A ++g++eiv+ Lle+   ++    ++g+ +L +A++ gh ++v++L 
  EEA22749.1 553 LVASYRGHVEVVQRLLeRGAEVNaQggFYGNALQAASSGGHIEIVQRLLEKgaeVNaqggDYGN-ALLAASSGGHVDVVQVLQ 634
                 678889*9*********99***98568667********************88674455666775.9*999988*******995 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       3.6   8.1e+03      17      28 ..     383     394 ..     380     398 .. 0.81
   2 !   13.9   0.0   2.3e-05     0.052      10      54 ..     410     454 ..     401     456 .. 0.89
   3 !   11.8   0.0    0.0001      0.23      22      54 ..     454     487 ..     453     489 .. 0.90
   4 ?    4.7   0.0     0.018        41      18      53 ..     484     519 ..     479     521 .. 0.83
   5 !   14.8   0.0   1.2e-05     0.027      16      52 ..     514     551 ..     503     553 .. 0.78
   6 !   21.6   0.1   8.9e-08    0.0002       1      54 [.     534     586 ..     534     588 .. 0.85
   7 !   13.3   0.0   3.6e-05     0.081      18      52 ..     583     617 ..     579     621 .. 0.84
   8 ?    2.6   0.0     0.078   1.7e+02      18      35 ..     616     633 ..     611     636 .. 0.83

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 3.6
       Ank_5  17 ntpLhvAakyga 28 
                 +++Lhv+a +g+
  EEA22749.1 383 MNALHVSAFNGH 394
                 799***996665 PP

  == domain 2  score: 13.9 bits;  conditional E-value: 2.3e-05
       Ank_5  10 nrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltald 54 
                 n +d  g ++L +A+ +g++  v++Ll+ ga  n++ +r+ +al+
  EEA22749.1 410 NERDSTGANALQWASLRGHFKSVQRLLEKGAEVNAQGGRYGNALQ 454
                 66788999****************************999988886 PP

  == domain 3  score: 11.8 bits;  conditional E-value: 0.0001
       Ank_5  22 vAak.ygaadvvrlLlargadlnltdsrGltald 54 
                 +Aa+  g+ ++v++Ll+rga  n++ +++ +al+
  EEA22749.1 454 QAASfEGHIEIVQILLERGAEVNAQGGEYGNALQ 487
                 589999*******************999988876 PP

  == domain 4  score: 4.7 bits;  conditional E-value: 0.018
       Ank_5  18 tpLhvAakygaadvvrlLlargadlnltdsrGltal 53 
                 ++L  A+  g+ ++v++L + ga  n++ +r+ +al
  EEA22749.1 484 NALQAASLEGHVEIVQRLPEKGAEVNAQGGRYGNAL 519
                 66666777*******************999987776 PP

  == domain 5  score: 14.8 bits;  conditional E-value: 1.2e-05
       Ank_5  16 gn.tpLhvAakygaadvvrlLlargadlnltdsrGlta 52 
                 ++ ++L  A+++g+ ++v++Ll+ ga  n++ +++ +a
  EEA22749.1 514 RYgNALQAASSGGHIEIVQKLLEKGAEVNAQGGDYGNA 551
                 33399999999*******************99888544 PP

  == domain 6  score: 21.6 bits;  conditional E-value: 8.9e-08
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltald 54 
                 Lle+g a vn++ g+  ++L vA+++g+ +vv++Ll+rga  n++ + + +al+
  EEA22749.1 534 LLEKG-AEVNAQGGDYGNALLVASYRGHVEVVQRLLERGAEVNAQGGFYGNALQ 586
                 78999.77777655544***************************9988877776 PP

  == domain 7  score: 13.3 bits;  conditional E-value: 3.6e-05
       Ank_5  18 tpLhvAakygaadvvrlLlargadlnltdsrGlta 52 
                 ++L  A+++g+ ++v++Ll+ ga  n++ +++ +a
  EEA22749.1 583 NALQAASSGGHIEIVQRLLEKGAEVNAQGGDYGNA 617
                 66667888*******************99988554 PP

  == domain 8  score: 2.6 bits;  conditional E-value: 0.078
       Ank_5  18 tpLhvAakygaadvvrlL 35 
                 ++L  A+++g+ dvv++L
  EEA22749.1 616 NALLAASSGGHVDVVQVL 633
                 77777888********98 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0       0.3   6.8e+02       4      21 ..     384     401 ..     383     414 .. 0.67
   2 !    9.2   0.0   0.00079       1.8       4      30 ..     418     445 ..     415     446 .. 0.89
   3 !   13.0   0.0     5e-05      0.11       5      30 ..     452     478 ..     451     479 .. 0.89
   4 ?    3.2   0.0     0.063   1.4e+02       5      30 ..     485     511 ..     484     512 .. 0.83
   5 !   12.3   0.0   8.4e-05      0.19       5      30 ..     518     544 ..     517     545 .. 0.91
   6 !   13.6   0.0   3.1e-05      0.07       5      30 ..     551     577 ..     550     578 .. 0.91
   7 !   12.9   0.0   5.2e-05      0.12       5      30 ..     584     610 ..     583     611 .. 0.91
   8 ?    0.5   0.0      0.45     1e+03       6      21 ..     618     633 ..     616     636 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.3
                 BHHHHHHHHTTHHHHHHH CS
         Ank   4 TPLHlAatngkkriiklL 21 
                  +LH+ a ng+  +i+ L
  EEA22749.1 384 NALHVSAFNGHDVVISKL 401
                 59***9988886555544 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00079
                 BHHHHHHHHTTHHHHHHHH.TTTSTTCB CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnlnal 30 
                  +L +A+ +g+   ++ LL +GA++na+
  EEA22749.1 418 NALQWASLRGHFKSVQRLLeKGAEVNAQ 445
                 68999**999999******99*****98 PP

  == domain 3  score: 13.0 bits;  conditional E-value: 5e-05
                 HHHHHHHHTTHHHHHHHH.TTTSTTCB CS
         Ank   5 PLHlAatngkkriiklLL.hGAnlnal 30 
                 +L  A+ +g+ +i++ LL +GA++na+
  EEA22749.1 452 ALQAASFEGHIEIVQILLeRGAEVNAQ 478
                 67778999**********99*****98 PP

  == domain 4  score: 3.2 bits;  conditional E-value: 0.063
                 HHHHHHHHTTHHHHHHHH..TTTSTTCB CS
         Ank   5 PLHlAatngkkriiklLL..hGAnlnal 30 
                 +L  A+ +g+++i++  L  +GA++na+
  EEA22749.1 485 ALQAASLEGHVEIVQR-LpeKGAEVNAQ 511
                 67778999*******9.55669***997 PP

  == domain 5  score: 12.3 bits;  conditional E-value: 8.4e-05
                 HHHHHHHHTTHHHHHHHH.TTTSTTCB CS
         Ank   5 PLHlAatngkkriiklLL.hGAnlnal 30 
                 +L  A+++g+ +i++ LL +GA++na+
  EEA22749.1 518 ALQAASSGGHIEIVQKLLeKGAEVNAQ 544
                 6778999***********99*****98 PP

  == domain 6  score: 13.6 bits;  conditional E-value: 3.1e-05
                 HHHHHHHHTTHHHHHHHH.TTTSTTCB CS
         Ank   5 PLHlAatngkkriiklLL.hGAnlnal 30 
                 +L +A+++g++++++ LL +GA++na+
  EEA22749.1 551 ALLVASYRGHVEVVQRLLeRGAEVNAQ 577
                 6778999***********99*****98 PP

  == domain 7  score: 12.9 bits;  conditional E-value: 5.2e-05
                 HHHHHHHHTTHHHHHHHH.TTTSTTCB CS
         Ank   5 PLHlAatngkkriiklLL.hGAnlnal 30 
                 +L  A+++g+ +i++ LL +GA++na+
  EEA22749.1 584 ALQAASSGGHIEIVQRLLeKGAEVNAQ 610
                 6778999***********99*****98 PP

  == domain 8  score: 0.5 bits;  conditional E-value: 0.45
                 HHHHHHHTTHHHHHHH CS
         Ank   6 LHlAatngkkriiklL 21 
                 L  A+++g++++++ L
  EEA22749.1 618 LLAASSGGHVDVVQVL 633
                 5567799******987 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0       1.2   2.7e+03       3      21 ..     383     401 ..     382     407 .. 0.80
   2 !   10.6   0.0   0.00031       0.7       2      31 .]     416     444 ..     415     444 .. 0.93
   3 !    8.1   0.0    0.0021       4.7       5      31 .]     452     477 ..     449     477 .. 0.86
   4 ?    1.2   0.0      0.36     8e+02       5      31 .]     485     510 ..     482     510 .. 0.88
   5 !    9.7   0.0   0.00063       1.4       5      31 .]     518     543 ..     515     543 .. 0.85
   6 !   11.2   0.0   0.00021      0.48       4      31 .]     550     576 ..     547     576 .. 0.93
   7 !    9.9   0.0   0.00056       1.3       5      31 .]     584     609 ..     581     609 .. 0.85
   8 ?   -1.3   0.0       2.4   5.5e+03       5      21 ..     617     633 ..     614     636 .. 0.76

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 1.2
       Ank_3   3 etpLhlAarsgnleivkfL 21 
                 +++Lh+ a +g+  ++  L
  EEA22749.1 383 MNALHVSAFNGHDVVISKL 401
                 579********98776655 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00031
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvna 31 
                 G ++L +A + g+++ v+ Lle kga+vna
  EEA22749.1 416 GANALQWASLRGHFKSVQRLLE-KGAEVNA 444
                 7899**********88******.9****96 PP

  == domain 3  score: 8.1 bits;  conditional E-value: 0.0021
       Ank_3   5 pLhlAarsgnleivkfLlenkgadvna 31 
                 +L  A   g++eiv+ Lle +ga+vna
  EEA22749.1 452 ALQAASFEGHIEIVQILLE-RGAEVNA 477
                 567777889999*******.9****96 PP

  == domain 4  score: 1.2 bits;  conditional E-value: 0.36
       Ank_3   5 pLhlAarsgnleivkfLlenkgadvna 31 
                 +L  A + g++eiv+ L e kga+vna
  EEA22749.1 485 ALQAASLEGHVEIVQRLPE-KGAEVNA 510
                 78889999*********99.8999996 PP

  == domain 5  score: 9.7 bits;  conditional E-value: 0.00063
       Ank_3   5 pLhlAarsgnleivkfLlenkgadvna 31 
                 +L  A + g++eiv+ Lle kga+vna
  EEA22749.1 518 ALQAASSGGHIEIVQKLLE-KGAEVNA 543
                 667777788889*******.9****96 PP

  == domain 6  score: 11.2 bits;  conditional E-value: 0.00021
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadvna 31 
                 ++L +A   g++e+v+ Lle +ga+vna
  EEA22749.1 550 NALLVASYRGHVEVVQRLLE-RGAEVNA 576
                 68999***************.9****96 PP

  == domain 7  score: 9.9 bits;  conditional E-value: 0.00056
       Ank_3   5 pLhlAarsgnleivkfLlenkgadvna 31 
                 +L  A + g++eiv+ Lle kga+vna
  EEA22749.1 584 ALQAASSGGHIEIVQRLLE-KGAEVNA 609
                 667777788889*******.9****96 PP

  == domain 8  score: -1.3 bits;  conditional E-value: 2.4
       Ank_3   5 pLhlAarsgnleivkfL 21 
                 +L  A + g++++v+ L
  EEA22749.1 617 ALLAASSGGHVDVVQVL 633
                 67777788888999887 PP

>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.2   0.0   3.6e-09   8.2e-06       3     226 ..      20     309 ..      18     315 .. 0.74

  Alignments for each domain:
  == domain 1  score: 25.2 bits;  conditional E-value: 3.6e-09
                 EEEESSH...HHHHHHHHHEEEEEEEEEE.TTEEEEEEEETTEEEEEEE--S.SHHHHHHHHHHHHHHHC.--SEEEEEEEEEES...STTT-TT-EEE CS
   PNP_UDP_1   3 aiivgsp...gevellaespleetpfgregrgfkfvtGtlkgkpvvivstGi.Gkpnaavvaeirllkef.gvkaiiriGtaGgl...npdlkvGDvvi 93 
                 + i+++p     ++ l++   e+++ + ++ + ++++G++++++v i++  + G+  aa +a+  +   f + +  + +G+ Gg+   ++d+++GD+++
  EEA22749.1  20 GWICAIPcelTAARELLDACHEQLESQAKHDENNYILGRMGKHNVAIACLPEyGTNRAA-IAAKSMQSTFpNLRFGVLVGVGGGVpsaQNDIRLGDIAV 117
                 66888885553333333336999999999*******************99964888888.8888888889544555999******999*********** PP

                 EEE......EEESSSCCGCCTHHCC............................................................TCCCCTTSSEE--H CS
   PNP_UDP_1  94 pdd......ainfdgrsplygpkee............................................................gqyfpdsydapadp 126
                 +        +i++d++++      e                                                            +   p++  +  +p
  EEA22749.1 118 SLPsgqdggVIQYDLGRR------EvdgfhrrgtlnkpptllrtaitnlrairklpqeisnlvnevfggdedseeewtypsnskdILFKPAHKHVNKNP 210
                 999334444455555554......4444556679999******************************99999999966666666655555555555556 PP

                 HHHHHHHH........CHHTTTTTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTBETTCTCH.HCCCHH CS
   PNP_UDP_1 127 elrallke........aaealgikvhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArelgipfaairvvsdlaaggadaeatheeveef 217
                 ++ a+++         + + +++++h+G +++++ +  +  +++ l  r  + + eME+a +       + p+++ir++ d+a+ +  +    + +  +
  EEA22749.1 211 DCDACVRDptgivtwdPRRGTNPRIHYGNIGSGNAVIKDALERDFLAGRDSILCFEMEAAGLMD-----DFPCVVIRGICDYADSHKNK----KWQPYA 300
                 6666655566666665555555******************99999*************987644.....79**********55553333....333444 PP

                 HHHHHHHHH CS
   PNP_UDP_1 218 aqeaaknaa 226
                 a++aa  a+
  EEA22749.1 301 AAIAAAYAK 309
                 444444444 PP

>> YajC  Preprotein translocase subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0     0.015        33      29      55 ..     430     456 ..     426     473 .. 0.73
   2 ?    0.6   0.0      0.24   5.3e+02      35      51 ..     469     485 ..     461     501 .. 0.81
   3 ?   -0.3   0.0      0.44   9.8e+02      36      50 ..     503     517 ..     491     531 .. 0.82
   4 ?    2.1   0.1     0.079   1.8e+02      32      50 ..     532     550 ..     520     565 .. 0.82
   5 !    5.1   0.0    0.0095        21      32      51 ..     565     584 ..     556     598 .. 0.81
   6 ?    1.1   0.0      0.16   3.6e+02      33      50 ..     599     616 ..     593     618 .. 0.85

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.015
        YajC  29 kemlasLkkGdeVvtigGivGkvvkvd 55 
                 k+ ++ L+kG eV  +gG +G+  +  
  EEA22749.1 430 KSVQRLLEKGAEVNAQGGRYGNALQAA 456
                 5677889**************876655 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.24
        YajC  35 LkkGdeVvtigGivGkv 51 
                 L++G eV  +gG +G+ 
  EEA22749.1 469 LERGAEVNAQGGEYGNA 485
                 89************985 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.44
        YajC  36 kkGdeVvtigGivGk 50 
                 +kG eV  +gG +G+
  EEA22749.1 503 EKGAEVNAQGGRYGN 517
                 69***********97 PP

  == domain 4  score: 2.1 bits;  conditional E-value: 0.079
        YajC  32 lasLkkGdeVvtigGivGk 50 
                 ++ L+kG eV  +gG +G+
  EEA22749.1 532 QKLLEKGAEVNAQGGDYGN 550
                 4459***********9997 PP

  == domain 5  score: 5.1 bits;  conditional E-value: 0.0095
        YajC  32 lasLkkGdeVvtigGivGkv 51 
                 ++ L++G eV  +gG++G+ 
  EEA22749.1 565 QRLLERGAEVNAQGGFYGNA 584
                 45599*************75 PP

  == domain 6  score: 1.1 bits;  conditional E-value: 0.16
        YajC  33 asLkkGdeVvtigGivGk 50 
                 + L+kG eV  +gG +G+
  EEA22749.1 599 RLLEKGAEVNAQGGDYGN 616
                 559***********9995 PP

>> Toprim_C_rpt  Topoisomerase C-terminal repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.0      0.03        68       3      16 ..     437     450 ..     437     457 .. 0.91
   2 ?   -1.4   0.0       1.1   2.5e+03       3      16 ..     470     483 ..     470     488 .. 0.89
   3 ?    6.9   0.0    0.0028       6.2       2      16 ..     502     516 ..     502     524 .. 0.95
   4 ?   -1.8   0.1       1.5   3.3e+03       3      16 ..     536     549 ..     536     550 .. 0.91
   5 ?   -1.9   0.1       1.5   3.4e+03       4      16 ..     570     582 ..     569     609 .. 0.81
   6 ?   -1.7   0.1       1.3     3e+03       3      16 ..     602     615 ..     601     616 .. 0.91

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.03
  Toprim_C_rpt   3 etgepikvkeGRfG 16 
                   e g +++++ GR+G
    EEA22749.1 437 EKGAEVNAQGGRYG 450
                   6799********** PP

  == domain 2  score: -1.4 bits;  conditional E-value: 1.1
  Toprim_C_rpt   3 etgepikvkeGRfG 16 
                   e g +++++ G +G
    EEA22749.1 470 ERGAEVNAQGGEYG 483
                   5699*********9 PP

  == domain 3  score: 6.9 bits;  conditional E-value: 0.0028
  Toprim_C_rpt   2 PetgepikvkeGRfG 16 
                   Pe g +++++ GR+G
    EEA22749.1 502 PEKGAEVNAQGGRYG 516
                   9************** PP

  == domain 4  score: -1.8 bits;  conditional E-value: 1.5
  Toprim_C_rpt   3 etgepikvkeGRfG 16 
                   e g +++++ G +G
    EEA22749.1 536 EKGAEVNAQGGDYG 549
                   6799*********9 PP

  == domain 5  score: -1.9 bits;  conditional E-value: 1.5
  Toprim_C_rpt   4 tgepikvkeGRfG 16 
                    g +++++ G +G
    EEA22749.1 570 RGAEVNAQGGFYG 582
                   6899999999999 PP

  == domain 6  score: -1.7 bits;  conditional E-value: 1.3
  Toprim_C_rpt   3 etgepikvkeGRfG 16 
                   e g +++++ G +G
    EEA22749.1 602 EKGAEVNAQGGDYG 615
                   6799*********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (640 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       422  (0.0235373); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.64u 0.28s 00:00:00.92 Elapsed: 00:00:00.44
# Mc/sec: 4347.27
//
Query:       EEA22750.1  [L=216]
Description: hypothetical protein PMAA_093660 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (216 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       315  (0.0175693); expected 358.6 (0.02)
Passed bias filter:                      301  (0.0167884); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.43u 0.26s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1574.37
//
Query:       EEA22751.1  [L=590]
Description: COPII vesicles protein Yip3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.6e-31  106.9   1.0    9.5e-31  106.3   1.0    1.2  1  PRA1            PRA1 family protein
     0.0082   16.3  20.6      0.027   14.6   3.1    2.2  2  YL1             YL1 nuclear protein
  ------ inclusion threshold ------
      0.022   14.5   0.5        8.7    6.2   0.2    2.6  2  CW_7            CW_7 repeat
        3.6    7.2  26.8        2.9    7.6  16.9    2.2  2  Cwf_Cwc_15      Cwf15/Cwc15 cell cycle control protein
        4.6    7.5  12.2         12    6.2  12.2    1.6  1  DUF4611         Domain of unknown function (DUF4611)
          9    4.2  17.2         15    3.5  17.2    1.2  1  DNA_pol_phi     DNA polymerase phi


Domain annotation for each model (and alignments):
>> PRA1  PRA1 family protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.3   1.0   3.2e-34   9.5e-31       2     126 ..      30     154 ..      29     156 .. 0.97

  Alignments for each domain:
  == domain 1  score: 106.3 bits;  conditional E-value: 3.2e-34
        PRA1   2 elaplRpwsefldlsrfslPkslskatsRvkkNllyfrtNYlivvllvlllslltnplslivllllvlawlflyflrseplvlfgrelsdrvvlivllv 100
                 ++a+l+p+sefld++r+s+P+++s+++sRv++Nl+yf++NY++v+l+++++ lltnp+ l+v++l++ +++ + +l  ++l ++  + s+++++++ll+
  EEA22751.1  30 RFANLKPISEFLDVKRISKPADFSEVQSRVNYNLSYFSSNYFVVFLMLSIYGLLTNPILLFVIVLVAGGMYGIGKLDGRDLDVGFLRASTSQLYTALLI 128
                 6899*********************************************************************************************** PP

        PRA1 101 vsvlllfltgavlvllwalliglllv 126
                 ++v+l +++++++  lw +++  +++
  EEA22751.1 129 IAVPLGLWASPISFALWLIGATGVTT 154
                 ********************988876 PP

>> YL1  YL1 nuclear protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   3.1     9e-06     0.027      36     147 ..     246     369 ..     221     404 .. 0.70
   2 !    7.4   9.8    0.0014       4.3      43      76 ..     527     560 ..     522     586 .. 0.64

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 9e-06
                 xxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxx. RF
         YL1  36 efeseeeeeeeensDsdfdsdeedee......sdeeedeeegekelerqerkkr..kkekkkrkaqkkkskkkkkkqkkkkkkkidp........qak. 117
                 ++ese +e  e  +D  +d+d +         +  +++e   ek ler +r++   kk+ + ++++  + ++ + k ++++kk++          +++ 
  EEA22751.1 246 DYESELSEGAE--FD--LDDDADSTVayavqlAMRDKEEMLVEKALERIRRAQMlgKKNVRLSQEELDALERRR-KGITNNKKSTVTipigspgrASTv 339
                 66666655443..55..655554334779999999999999************977665566554444444444.555555554444689998873333 PP

                 .xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         YL1 118 .eprpkkkseraswlpaeslltpkrRkssRa 147
                  + rp+++++ a+ +p++s  +++ R+ss +
  EEA22751.1 340 nDRRPRSRESVAKVSPKASGASES-RRSSQS 369
                 233777777666667766664555.555444 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0014
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         YL1  43 eeeeensDsdfdsdeedeesdeeedeeegekele 76 
                  e+e+++D d d+d++d+++d+++d++eg +  +
  EEA22751.1 527 SEDESSDDHDSDEDDDDDDDDDDDDDDEGVQVTQ 560
                 2333235555566666556666666666655444 PP

>> CW_7  CW_7 repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   0.0    0.0038        11      27      38 ..      50      61 ..      44      63 .. 0.85
   2 ?    6.2   0.2    0.0029       8.7      17      30 ..     235     248 ..     227     249 .. 0.91

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0038
        CW_7 27 ydYdaVQarVNe 38
                 d+++VQ+rVN 
  EEA22751.1 50 ADFSEVQSRVNY 61
                699********6 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.0029
        CW_7  17 eRkkrLtaaGydYd 30 
                 +R+ rL++ GydY+
  EEA22751.1 235 ARELRLRNNGYDYE 248
                 7999*********7 PP

>> Cwf_Cwc_15  Cwf15/Cwc15 cell cycle control protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   2.2    0.0052        16     132     187 ..     256     321 ..     186     351 .. 0.73
   2 ?    7.6  16.9   0.00097       2.9     114     145 ..     525     554 ..     491     561 .. 0.50

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.0052
                 -----------..........--------------------------------------------- CS
  Cwf_Cwc_15 132 dsdsdsddddd..........edetaeLlrELekikreraeekerkerekaeeeekereeeiatgN 187
                 + d d+d d+           + e+    + Le+i+r ++  k+    +++e ++ er+++ +t+N
  EEA22751.1 256 EFDLDDDADSTvayavqlamrDKEEMLVEKALERIRRAQMLGKKNVRLSQEELDALERRRKGITNN 321
                 3333333333367778888867777788899*********99999999999999999999988888 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.00097
                 -------------------------------- CS
  Cwf_Cwc_15 114 ddedseeeeeeeeeesdddsdsdsdddddede 145
                 + +++ e +++++++++dd+d+d+ddddd+de
  EEA22751.1 525 EVSED-E-SSDDHDSDEDDDDDDDDDDDDDDE 554
                 22222.2.122222223333333333333333 PP

>> DUF4611  Domain of unknown function (DUF4611)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2  12.2    0.0039        12      47      81 ..     524     559 ..     512     567 .. 0.64

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.0039
     DUF4611  47 stlveqeaqddvaaagdeeeegededdeeee.knik 81 
                 +++ e e +dd ++++d++++++d+dd+++e  +++
  EEA22751.1 524 DEVSEDESSDDHDSDEDDDDDDDDDDDDDDEgVQVT 559
                 445666788888888887777655555554414544 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5  17.2     0.005        15     651     679 ..     526     554 ..     513     571 .. 0.50

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.005
  DNA_pol_phi 651 eeeeddeededseedddeeesdedeeded 679
                   +e+++++d ds+eddd++++d+d++d++
   EEA22751.1 526 VSEDESSDDHDSDEDDDDDDDDDDDDDDE 554
                  22222333333333333333333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (590 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       971  (0.0541581); expected 358.6 (0.02)
Passed bias filter:                      546  (0.0304535); expected 358.6 (0.02)
Passed Vit filter:                       100  (0.00557756); expected 17.9 (0.001)
Passed Fwd filter:                        26  (0.00145016); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.77u 0.33s 00:00:01.10 Elapsed: 00:00:00.46
# Mc/sec: 3832.56
//
Query:       EEA22752.1  [L=280]
Description: FK506 suppressor Sfk1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.6e-47  161.2  11.3      3e-47  161.0  11.3    1.0  1  Frag1     Frag1/DRAM/Sfk1 family
  ------ inclusion threshold ------
      0.025   14.7   0.6       0.14   12.3   0.0    2.4  2  CBP_BcsF  Cellulose biosynthesis protein BcsF
        9.6    4.4  11.3        3.8    5.7   8.7    1.5  1  DUF2070   Predicted membrane protein (DUF2070)


Domain annotation for each model (and alignments):
>> Frag1  Frag1/DRAM/Sfk1 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  161.0  11.3     5e-51     3e-47       2     216 ..       6     221 ..       5     224 .. 0.94

  Alignments for each domain:
  == domain 1  score: 161.0 bits;  conditional E-value: 5e-51
       Frag1   2 ffllpliafilwlgmliamlvcavvqgpvdyvfmhkeqflPyISdigatnpeslffslalnlglflvilvallrfqr....lpplatksernlnfaalv 96 
                 f+++p+i++ +wl+mliam+ +++++g+ +y +m    ++PyISdigat  ++lf++ ++++ +fl ++++++r++r    l ++  + ++ +++++++
  EEA22752.1   6 FWVFPVISACMWLAMLIAMISTWAAKGKPHYSNMPARRTIPYISDIGATGIQPLFIAGSAVTVVFLDLSFLAERWLRhsgqLLRNKGRFDKACSIISII 104
                 899************************888****99999**************************************555544445555555******* PP

       Frag1  97 lgligalglllvsifstaeyhsvHlvgavvffvfgflyvllqtalyykmgrhy..vwnkstisfrlkvvllilavvlailfgvffvrhkkkcgygaysl 193
                 + ++ga gl+l+sif+  +y +vH+++ ++f+ ++++++++ +++y+++g  y  +++   +sf++k++++++ + lai+fgv++ r      +g   +
  EEA22752.1 105 FSFLGAAGLILLSIFNDVDYDEVHDSMLGLFIGGYLISAIFICLEYLRLGVAYrkQHRVLFVSFWIKLLFIVIELGLAISFGVLSRR-----TPGGTDA 198
                 *****************************************************999999****************************.....6899*** PP

       Frag1 194 sAifEWllafwfiiffltfsvDF 216
                 +A++EW++af+f +++l+f++D+
  EEA22752.1 199 AAVLEWVIAFVFTFYVLSFIIDL 221
                 **********************8 PP

>> CBP_BcsF  Cellulose biosynthesis protein BcsF
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   2.3e-05      0.14      13      37 ..      66      90 ..      64      97 .. 0.92
   2 ?   -1.1   0.2      0.35   2.1e+03      15      31 ..     143     159 ..     139     166 .. 0.66

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 2.3e-05
    CBP_BcsF 13 caLiflpLgyllarllrrlsdtlrl 37
                ++++fl L  l+ r+lr++ + lr+
  EEA22752.1 66 VTVVFLDLSFLAERWLRHSGQLLRN 90
                689******************9997 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.35
    CBP_BcsF  15 LiflpLgyllarllrrl 31 
                  if+ L yl   +  r+
  EEA22752.1 143 AIFICLEYLRLGVAYRK 159
                 58999999865555444 PP

>> DUF2070  Predicted membrane protein (DUF2070)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.7   8.7   0.00063       3.8      21     122 ..     103     222 ..      93     233 .. 0.61

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.00063
     DUF2070  21 iillalligllaflssk..........lfgillfglpalvaflltlpvlrilggr.ltykrslflalltelivviisllaillsall........qalv 100
                 ii+  l ++ l  ls++           +  l++g  ++ a+++ l  lr+      +  r lf+++ + l++++i l  ++ + +l         a  
  EEA22752.1 103 IIFSFLGAAGLILLSIFndvdydevhdSMLGLFIGGYLISAIFICLEYLRLG-VAyRKQHRVLFVSFWIKLLFIVIELGLAISFGVLsrrtpggtDAAA 200
                 2222222222222333356788888775556677777777777777777664.332444555*************999999999999999955544444 PP

     DUF2070 101 llalvlslalvfalrllvlvav 122
                 +l +v++++++f +  +++ ++
  EEA22752.1 201 VLEWVIAFVFTFYVLSFIIDLL 222
                 4455555555555555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (280 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       664  (0.037035); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.31s 00:00:00.83 Elapsed: 00:00:00.47
# Mc/sec: 1799.37
//
Query:       EEA22753.1  [L=277]
Description: tyrosine/serine protein phosphatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.1e-36  126.1   0.0    2.9e-36  125.6   0.0    1.2  1  Y_phosphatase3  Tyrosine phosphatase family
    4.3e-08   32.9   0.0    6.8e-08   32.3   0.0    1.3  1  Y_phosphatase2  Tyrosine phosphatase family
     0.0031   17.1   0.0     0.0046   16.6   0.0    1.2  1  Y_phosphatase   Protein-tyrosine phosphatase
  ------ inclusion threshold ------
      0.021   14.6   0.0      0.034   14.0   0.0    1.4  1  DSPc            Dual specificity phosphatase, catalytic domai
      0.073   12.0   0.0       0.13   11.2   0.0    1.3  1  Myotub-related  Myotubularin-like phosphatase domain


Domain annotation for each model (and alignments):
>> Y_phosphatase3  Tyrosine phosphatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  125.6   0.0   8.1e-40   2.9e-36      23     231 ..       6     275 ..       3     276 .. 0.83

  Alignments for each domain:
  == domain 1  score: 125.6 bits;  conditional E-value: 8.1e-40
  Y_phosphatase3  23 vrpgvlyRsaelsklteadlakLad.lgirtviDLRspeErea...eap.........................legaryvhlpv.......... 78 
                     +++gvl+Rsa l++++e+d+++L d +++ tviDLRs++E      +                           l                    
      EEA22753.1   6 LKEGVLFRSARLDDASERDKHRLIDdINLLTVIDLRSHTEHVLatrR-RqislsltpseepsfpetadrphlldL---------Pgvkrhfislt 90 
                     799*******************9999**************5322221.134555555555565444444444444.........0566666666* PP

  Y_phosphatase3  79 .............................eeaaeeekeeeeaeetlaelYrellesakkayrkvfealad.ee.pvlfHCtaGKDRTGvlaalll 142
                                                  +ea +  +++  + + l  l ++ l+sa +++r+vf+ l + ++ pvl+HCt GKDRTG++++lll
      EEA22753.1  91 graferlllwrldwynfikviglltsgyrKEAIRVIATNVMKPRGLIGLGQDTLDSAGSEIRDVFNVLTSdDAyPVLIHCTQGKDRTGLIIMLLL 185
                     *********************9999876424577888888899999999999******************555********************** PP

  Y_phosphatase3 143 sll.....GvdeedivaDYlltneyleelrerlkakleeellaealeellsvrpeyleaaldaieekygsvegYlreelglseeeiealrerll 231
                      l+     +v+  +i+aDY  +++ l+++ e+l++++++       ee+ ++ p + ea  +++++kyg++++Yl  ++g +e++ie++r+rll
      EEA22753.1 186 LLVqetapDVPLTAIAADYSKSETELRPELESLMKEITDI---GLDEEYAKTPPGFTEALKEHLDTKYGGAKAYLL-SIGCEEANIEKIRRRLL 275
                     98855555799******************99996666444...346799**************************8.79*************97 PP

>> Y_phosphatase2  Tyrosine phosphatase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.3   0.0   1.9e-11   6.8e-08      71     115 ..     143     187 ..     114     204 .. 0.82

  Alignments for each domain:
  == domain 1  score: 32.3 bits;  conditional E-value: 1.9e-11
                     G----HHHHHHHHHHHH-GGG-SEEEE-SSSSSHHHHHHHHHHHH CS
  Y_phosphatase2  71 lveiksdllkkalklllnkenypvllhckrGkhrtglvigclRkl 115
                     +     ++++ ++++l   + ypvl+hc++Gk rtgl+i+ l  l
      EEA22753.1 143 TLDSAGSEIRDVFNVLTSDDAYPVLIHCTQGKDRTGLIIMLLLLL 187
                     556667899*******************************98655 PP

>> Y_phosphatase  Protein-tyrosine phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.6   0.0   1.3e-06    0.0046     167     198 ..     160     191 ..     141     208 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.6 bits;  conditional E-value: 1.3e-06
                    STTSS-EEEECSSSSHHHHHHHHHHHHHHHHH CS
  Y_phosphatase 167 eaksgpvvVhCsaGvgRtgtfvaldillqqle 198
                    +++  pv++hC +G  Rtg +++l +ll q +
     EEA22753.1 160 SDDAYPVLIHCTQGKDRTGLIIMLLLLLVQET 191
                    34589******************999987755 PP

>> DSPc  Dual specificity phosphatase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   9.4e-06     0.034      71      96 ..     161     186 ..     141     223 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 9.4e-06
                 HTT-EEEEEESSSSSHHHHHHHHHHH CS
        DSPc  71 qkgkkvlVHCqaGisRSatliiaYlm 96 
                 ++   vl+HC+ G  R++ +i+  l+
  EEA22753.1 161 DDAYPVLIHCTQGKDRTGLIIMLLLL 186
                 56789****************97766 PP

>> Myotub-related  Myotubularin-like phosphatase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   3.6e-05      0.13     232     257 ..     163     188 ..     150     192 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 3.6e-05
                     ---EEEE-SSSSSHHHHHHHHHHHHH CS
  Myotub-related 232 kssvLvhcsdGwDrtsqlsslaqllL 257
                     + +vL+hc++G Drt  ++ l  ll+
      EEA22753.1 163 AYPVLIHCTQGKDRTGLIIMLLLLLV 188
                     568**************999988776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (277 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       312  (0.017402); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.55u 0.26s 00:00:00.81 Elapsed: 00:00:00.49
# Mc/sec: 1710.37
//
Query:       EEA22754.1  [L=999]
Description: beta-galactosidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    6.5e-80  269.1   3.9    9.9e-80  268.5   3.9    1.2  1  Glyco_hydro_35  Glycosyl hydrolases family 35
    1.5e-55  186.6   4.7    5.7e-29  101.0   0.0    3.4  3  BetaGal_dom4_5  Beta-galactosidase jelly roll domain
    3.3e-50  170.4   7.1    6.3e-50  169.5   7.1    1.5  1  BetaGal_dom2    Beta-galactosidase, domain 2
      3e-24   84.4   0.0    9.2e-24   82.8   0.0    1.9  1  BetaGal_dom3    Beta-galactosidase, domain 3
    5.2e-05   22.7   0.0     0.0065   15.9   0.0    2.3  2  Glyco_hydro_42  Beta-galactosidase
    0.00026   20.5   0.2     0.0034   16.8   0.1    2.3  2  Cellulase       Cellulase (glycosyl hydrolase family 5)


Domain annotation for each model (and alignments):
>> Glyco_hydro_35  Glycosyl hydrolases family 35
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  268.5   3.9   3.3e-83   9.9e-80       1     312 [.      36     371 ..      36     374 .. 0.89

  Alignments for each domain:
  == domain 1  score: 268.5 bits;  conditional E-value: 3.3e-83
                     SEEETTEEE-EEEEEE-GGGS-.GGGHHHHHHHHHHCT-SEEEEE--HHHH-SCTTB---S.GGG-CHHHHHHHHHCT-EEEEEEES---TTBGG CS
  Glyco_hydro_35   1 sllidgerflllsGeihyfRlp.pelWedvlekvkalGlnaietYveWnlhepkegkydfe.GaldlekFlklaqeagLyvilRpGpYicaEwda 93 
                     sl i+ger+++++Ge+hy+Rlp pelW dv++k+ka G+nai++Y+ Wn h+ +eg ydfe G ++++++++ a++ag+y+i+RpGpY ++E++a
      EEA22754.1  36 SLSINGERLFVFAGEFHYIRLPvPELWLDVFQKLKANGFNAISVYFYWNHHSASEGVYDFEtGGHNVQRLFDYAKQAGVYIIARPGPYANGELSA 130
                     588*********************************************************99********************************* PP

                     GG--GGGGGSTTS-TTSS-HHHHHHCHHHHHHHHHHHHHCBGGGTSSEEEEEESSSGG.....GT---HHHHHHHHHHHC.CCT-SSCBEEECES CS
  Glyco_hydro_35  94 GGlpaWllkkkeiklRssdeafleavekyleailkkvkkllltnGGpiilvQvEneYg.....skavdkaylralakalk.eklaekallftadv 182
                     GG+++W  + + +  R++d+++ + ++ ++++i k+++  ++t+GGp+ilvQ Ene       ++++   y++++ + l  + ++ + +++++++
      EEA22754.1 131 GGYALWAANGRLGGERTRDSQYYDLWSPWMTKIGKIIAANQITEGGPVILVQHENELQetthrANNTLVLYMEQITQILDaAGIVVPSTHNEKGM 225
                     *********************************************************98776666666679987777665155677888999988 PP

                     TTTCCCTTS.STT.T.SCEEEEEECTTS.T..........HHHHHHHHHH-TTS--EEEEEESS---BTTS--HHHHHHHCCHHHHHHHCCC... CS
  Glyco_hydro_35 183 pseevaekg.tlp.eedilatvgfgsdaka..........keafkllkefspekPlvvsefwtgwfdewgekkaarsaeelaeevervlakn... 262
                     +s++++ +  ++  + +i+  ++++ +              ++++  +++s ++P  ++ef++g f++wg+  + ++a+ l+ e+++v++kn   
      EEA22754.1 226 RSMSWSMDYeDVGgAVNIYGLDSYPGGLSCtnpnagfnliRTYYQWFQNYSYTQPEYLAEFQGGYFTPWGGVFYDDCASMLQPEYADVFYKNnig 320
                     88877665433330344888888887733345567877777778888*********************************************9** PP

                     ...SEEEEEECE--B-GCC-B-CCTT.SB--TT-SB-TTS---HHHHHHHHH CS
  Glyco_hydro_35 263 ..issvnlYMihGGTnfGflaganflgtsYdydApldEagnltpkylelkel 312
                       +++++lYM +GGTn+G++a a++++tsYdy Apl E++++++k  + k l
      EEA22754.1 321 nrVTLQSLYMAYGGTNWGHIA-APVVYTSYDYSAPLRETREIRDKLKQTKLL 371
                     *9*******************.66666******************9998876 PP

>> BetaGal_dom4_5  Beta-galactosidase jelly roll domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0       1.1   3.3e+03      67      91 ..     484     509 ..     470     524 .. 0.80
   2 !   85.4   0.7   1.3e-27   3.9e-24       1     114 []     666     781 ..     666     781 .. 0.92
   3 !  101.0   0.0   1.9e-32   5.7e-29       1     113 [.     837     959 ..     837     960 .. 0.95

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 1.1
  BetaGal_dom4_5  67 vsvwlNGyqlgsyv.phigpqvtFpv 91 
                     + ++lN  q g++v ++  ++++++v
      EEA22754.1 484 LALYLNKGQTGTFVlANAASHLKYTV 509
                     5799********99877888888866 PP

  == domain 2  score: 85.4 bits;  conditional E-value: 1.3e-27
  BetaGal_dom4_5   1 Yderqgwhlpgkttsnnskwplt..vlyssdygfhagvrlyrgtfdldlpsgldvslsltlsggtafrvsvwlNGyqlgsyv.....phigpqvt 88 
                     Yd++ +w++++ktts n  +pl+  vlys+dyg+hag ++yrg+f    +s +++++ +t ++g+a+++s+wlNG ++g ++     + +++ ++
      EEA22754.1 666 YDDS-NWVVCNKTTSFNAIAPLSlpVLYSGDYGYHAGPKIYRGRF----GSTNATGVTVTAQNGNAAGWSAWLNGIYIGGVTgdpsiEATSAVLK 755
                     9***.****************************************....999****************************999*77666777778 PP

  BetaGal_dom4_5  89 Fpvpegilnyngenvlavlvdamged 114
                     F+  + + ++ +envl+vlvd++g+d
      EEA22754.1 756 FNSSTTLKQEGSENVLTVLVDYTGHD 781
                     877777555556************97 PP

  == domain 3  score: 101.0 bits;  conditional E-value: 1.9e-32
  BetaGal_dom4_5   1 Yderqgwhlpgkttsnnskwpltvlyssdyg.fhagvrlyrgtfdldlpsg...ldvslsltl...sggtafrvsvwlNGyqlgsyvphigpqvt 88 
                     Y+er gwhlpg+++s++s w+   + ++++g ++ ++r+y ++f+ldl+ +   ldv+++++l   s+++ ++++vwlNGy++++y+phigpq++
      EEA22754.1 837 YGERLGWHLPGFEPSTKSGWD---TRAPSDGvDGGSHRFYITEFTLDLGPNshaLDVPIGIHLnasSTSGPAVAYVWLNGYKFAHYLPHIGPQTV 928
                     9********************...67888887****************9988899***********999************************** PP

  BetaGal_dom4_5  89 Fpvpegilnyng......envlavlvdamge 113
                     Fp+++g+ln +g      +n+lav+++a+++
      EEA22754.1 929 FPFQPGVLNIQGseghkrKNTLAVSLWALTD 959
                     ***********99***************986 PP

>> BetaGal_dom2  Beta-galactosidase, domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  169.5   7.1   2.1e-53   6.3e-50       2     181 .]     382     556 ..     381     556 .. 0.89

  Alignments for each domain:
  == domain 1  score: 169.5 bits;  conditional E-value: 2.1e-53
                   SEE---BSS.SS.BS-TTEEEEEEE-.STT-EEEEEEESSTT---EEEE-EEEEETT.EEEEE-TTSS-EEEESS-EEEEEEEEEETTEEEEEESSE CS
  BetaGal_dom2   2 aktervgngtsyttsnsaiavtelrnpdtkasFyvvrhadysslestsfklkvnTsaaGnltiPqlggsltLngrdSKilVtDYdvGgktLlYStAE 98 
                   ++te++gngtsy t+ ++i++++lrnp+t+a+Fyvv + d+ss++++ f+l+v+Ts aG++ i +    + L+gr+SKi+ tDY+vG++tLlY++A+
    EEA22754.1 382 LQTEMEGNGTSY-TTGANIFTWALRNPETNAGFYVVAQDDSSSTTDVVFDLEVETS-AGSVNITN----IGLDGRQSKIITTDYKVGDTTLLYCSAD 472
                   689*********.6******************************************.6******9....**************************** PP

                   EEEEEEETTEEEEEEEE-TT-EEEEEEE-.......SS-..EEEEESTEEEE-SSEEEEEEE--SS.-EEEEET.TEEEEEEEHHHHTTE CS
  BetaGal_dom2  99 vlTwkklddktvlvlYggegetgefalkg.......kskgsssvvegskikskngalvlnwytqsegrtvvklgngllvylldrnsAynf 181
                   +lT+++l d +vl lY+++g+tg f+l++       + +g+s+v++    +++++ ++++ ytq++g++++k++n  lvylld+ +A++f
    EEA22754.1 473 ILTYATL-DVDVLALYLNKGQTGTFVLANaashlkyTVYGNSTVTS----SNSSQGTIYT-YTQGQGISAIKFSNRFLVYLLDKYTAWDF 556
                   *******.9*******************964433333333333333....3344448999.***************************98 PP

>> BetaGal_dom3  Beta-galactosidase, domain 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.8   0.0   3.1e-27   9.2e-24       5      77 .]     563     634 ..     557     634 .. 0.91

  Alignments for each domain:
  == domain 1  score: 82.8 bits;  conditional E-value: 3.1e-27
  BetaGal_dom3   5 ltssPaesenessviVkGpYLvRsasisgstLaltGDlnatttlevi.apssvktltwNgkklettktkyGslt 77 
                   l s+P++++ne +++V GpYLvR+a+i+g+tL+ltGD+++tt++e++     ++++twNgk+l+t++t+yGslt
    EEA22754.1 563 L-SDPNVKPNE-HIFVIGPYLVREATIKGRTLELTGDNQNTTSIEIYhGNPFITSITWNGKHLSTKRTAYGSLT 634
                   3.789999999.***********************************66689*******************985 PP

>> Glyco_hydro_42  Beta-galactosidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   2.2e-06    0.0065      10      68 ..      60     121 ..      54     137 .. 0.92
   2 !    4.4   0.0    0.0067        20     207     265 ..     194     254 ..     151     295 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 2.2e-06
                     CHHHHHHHHHHHHT--EEEE-TT-HHHH-SBTTB---HH....HHHHHHHHHCTT-EEEEE-S CS
  Glyco_hydro_42  10 eaweedirlmkeagvnvvrlgefaWaklePeegkydFew....LdevldllekagikviLatp 68 
                     e w + ++++k  g+n+++  +f W+ +  +eg ydFe      ++++d +++ag+++i +++
      EEA22754.1  60 ELWLDVFQKLKANGFNAIS-VYFYWNHHSASEGVYDFETgghnVQRLFDYAKQAGVYIIARPG 121
                     679999*************.7*****************99999***************98776 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.0067
                     HHHHHHHHHHHHHHHHHHHSTT-EEE-EE-TT...--SS-HHHHGGGSSSEEEEE-HH--- CS
  Glyco_hydro_42 207 ssdqilefvkaeaeilreyspdipvttnfmgs..afkdldyvklakeldivswdsYptrsk 265
                     ++++++ ++++ ++il ++   +p t+n  g+  +  ++dy +++  ++i   dsYp + +
      EEA22754.1 194 ANNTLVLYMEQITQILDAAGIVVPSTHNEKGMrsMSWSMDYEDVGGAVNIYGLDSYPGGLS 254
                     5666777888888899998889999**98777668899*******************9333 PP

>> Cellulase  Cellulase (glycosyl hydrolase family 5)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.1   1.2e-06    0.0034      23     133 ..      62     189 ..      27     247 .. 0.68
   2 ?    0.8   0.0     0.089   2.6e+02      32      54 ..     259     282 ..     255     289 .. 0.81

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 1.2e-06
                 HHHHHHHHHHHT-SEEEEEEECTGGTTSSTTTGCTHHHHHHHHHHHHHHHHTT-EEEEEEESS..........TTTCSSSSTTTTHHHHHHH....... CS
   Cellulase  23 tkalidevkdagfntvRlpvswgelvenapdykvdenslerveevvkyakenglyvildiHse..........egwltkadgnssedtaeef....... 104
                 + ++++++k++gfn++ + ++w+ +  +++++   e+   +v+ + +yak++g+y+i  +  +          ++w+ +++  ++ ++  ++       
  EEA22754.1  62 WLDVFQKLKANGFNAISVYFYWNHHS-ASEGVYDFETGGHNVQRLFDYAKQAGVYIIARPGPYangelsaggyALWAANGRLGGERTRDSQYydlwspw 159
                 56899*****************8888.4555534478999****************9877777777777777666644443333333333332222222 PP

                 HHHHHHHHH.HHHTTTTTTEEEESSSS--S CS
   Cellulase 105 fkklwtqiA.erykkndevvifelmNEPhg 133
                 ++k+ + iA ++ +   +v++    NE   
  EEA22754.1 160 MTKIGKIIAaNQITEGGPVILVQHENELQE 189
                 444444443134445555666666666666 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.089
                 HHT-SEEEEEEEC.TGGTTSSTTT CS
   Cellulase  32 dagfntvRlpvsw.gelvenapdy 54 
                 +agfn++R  + w +++  ++p+y
  EEA22754.1 259 NAGFNLIRTYYQWfQNYSYTQPEY 282
                 68***********87777667777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (999 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       479  (0.0267165); expected 358.6 (0.02)
Passed bias filter:                      397  (0.0221429); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.76u 0.31s 00:00:01.07 Elapsed: 00:00:00.48
# Mc/sec: 6260.34
//
Query:       EEA22755.1  [L=621]
Description: pogo transposable element, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.9e-24   86.2   0.0    3.6e-24   85.4   0.0    1.5  1  DDE_1         DDE superfamily endonuclease
    5.5e-09   35.9   0.1    2.4e-08   33.9   0.1    2.2  1  HTH_Tnp_Tc5   Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
      0.019   14.6  19.2      0.037   13.7  19.2    1.5  1  CAF-1_p150    Chromatin assembly factor 1 complex p150 subuni


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.4   0.0     6e-28   3.6e-24       2     175 .]     193     368 ..     192     368 .. 0.88

  Alignments for each domain:
  == domain 1  score: 85.4 bits;  conditional E-value: 6e-28
       DDE_1   2 erltvllcanaagsekLkplvigkaks..prafkngektkkkldveyksnrkawltssifeeWL.kvfdkrleaekrk..ilLlldssrshetvel.le 94 
                 +++ ++++++ a++  L p +i+ aks  ++ ++   +++++  + + +++ +w+ ++i+ +WL  vfdk ++++ ++   lL+ld+++sh t+++ + 
  EEA22755.1 193 REWITTIGCICANGTALAPSLIFMAKSgfIQDSWLQDYDPQTQRCFFAASESGWTNNDIGYRWLvDVFDKETKSQASRgwRLLILDGHGSHVTMKFiEY 291
                 678999*****************8887558999999*************************************666652267**************999 PP

       DDE_1  95 selqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                 ++++ i l+++Pa+++++lqPld+  +s+l + Y +ql   ++   +       +lt +d+++   ++wn  + +++i+saf
  EEA22755.1 292 CDSNRILLAIFPAHATHTLQPLDVALFSPLSNAYTKQLD-DFIRDSQG----FTRLTKRDFFRLFWASWNeVFISKNINSAF 368
                 ********************************9988754.44444433....4569**************666789999988 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.9   0.1     4e-12   2.4e-08       4      60 ..      61     108 ..      58     115 .. 0.91

  Alignments for each domain:
  == domain 1  score: 33.9 bits;  conditional E-value: 4e-12
                  HHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT CS
  HTH_Tnp_Tc5   4 lEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh 60 
                  + +aL++Wi+ql+erg p+t++++ + A+e+         + + ++k+W  r++k h
   EEA22755.1  61 QSRALIKWINQLTERGLPPTNSMLANFAREI---------SGKEPGKNWASRWLKAH 108
                  789****************************.........67889**********99 PP

>> CAF-1_p150  Chromatin assembly factor 1 complex p150 subunit, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7  19.2   6.3e-06     0.037      29     100 ..     492     563 ..     481     595 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 6.3e-06
  CAF-1_p150  29 lklerekeekkrlkeekkeekerakeearrkkeeekekkekerrekkekdekekaeklrlkeekrkekleal 100
                 +++  +k+++ + k+  k++k+  ++ +++ +e ek ++ + r+ek+e+ e+e aek+rlk+e+   kl  l
  EEA22755.1 492 RDIISQKNDEAAQKQAYKDDKKLQQQLKKQAREAEKVERAQIRQEKREQREQEAAEKQRLKDEQELAKLADL 563
                 444556777777777777777777777777888899999999**********************99988766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (621 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2834  (0.158068); expected 358.6 (0.02)
Passed bias filter:                      832  (0.0464053); expected 358.6 (0.02)
Passed Vit filter:                       115  (0.00641419); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.87u 0.30s 00:00:01.17 Elapsed: 00:00:00.47
# Mc/sec: 3977.86
//
Query:       EEA22756.1  [L=1499]
Description: copper-transporting ATPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.7e-45  153.7   6.2    1.3e-44  151.9   6.2    2.1  1  E1-E2_ATPase    E1-E2 ATPase
    4.1e-26   92.6   0.0    6.5e-26   91.9   0.0    1.3  1  Hydrolase       haloacid dehalogenase-like hydrolase
    2.4e-22   79.7  11.6    2.4e-22   79.7  11.6    2.9  2  FA_hydroxylase  Fatty acid hydroxylase superfamily
    7.5e-07   29.5   0.3      2e-06   28.1   0.1    1.9  2  HMA             Heavy-metal-associated domain


Domain annotation for each model (and alignments):
>> E1-E2_ATPase  E1-E2 ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  151.9   6.2   2.9e-48   1.3e-44       2     180 ..     626     815 ..     625     816 .. 0.97

  Alignments for each domain:
  == domain 1  score: 151.9 bits;  conditional E-value: 2.9e-48
                   SS--EEEEE..-TTS-EEEEGGG--TTSEEEEETT-B--SEEEEEEE-SEEE-TTTS---S-EE-G-TTEE-TT-EEEE-EEEEEEEE-TTTSTTTT CS
  E1-E2_ATPase   2 llpptakvi..rdgteeeidakelvpGDivllkagdrvpaDgrivegsaevdesaLTGEslpvekekgdmvfsGtvvvsgeakavVtatgedtelgk 96 
                   l+ pta+++   + +e+eid++ l+ GD++++ + +++p+Dg ++ gs+evdes++TGE  pvek   ++v +G+v+ sg+++++ t++  d++++ 
    EEA22756.1 626 LQTPTATLVdeSGANEKEIDVRLLQHGDVLKILPDSKIPTDGTVIGGSSEVDESMITGEPIPVEKFPASTVVAGSVNGSGTLIVKLTRLPADNTISV 722
                   788999999745559999******************************************************************************* PP

                   TSTTS--------HHHHHHHHHHHHHHHHHHHHHHHHHHS-STTTSSTT.........HHHHHHHHHHHHHS-TTHHHHHHHHHHHHHHHHHH CS
  E1-E2_ATPase  97 iarlveeakskktplqkkldklgkvlvpvvlliallvflialllgksla.........eallralallvaaiPcaLplavplalalgarrlak 180
                   ia lv +ak +k+++q ++d++++++vpvv+++++++f+i++ +g +++         ea++ a+++l++++Pca++lavp++++++ + +a+
    EEA22756.1 723 IAGLVDQAKLSKPRIQDIADRVASFFVPVVITLSIITFVIWIAVGITVRsqsgarattEAITYAITVLIVSCPCAIGLAVPMVIVIASGVAAE 815
                   ***********************************************99**************************************999886 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.9   0.0   1.4e-29   6.5e-26       4     208 ..     835    1047 ..     833    1049 .. 0.86

  Alignments for each domain:
  == domain 1  score: 91.9 bits;  conditional E-value: 1.4e-29
                  EEEESBTTTBCHH.HHHHHHHHHH.CHHHHHHHHHHHHCHHHHHHHHHHHHH..HHHH...HHHHHETTTE........HHHHTHHHHHHHHHCHHH CS
                  xxxxxxxxxxxxx.xxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxx...xxxxxxxxxx........xxxxxxxxxxxxxxxxxx RF
   Hydrolase    4 vvfDkdGTLttge.psvedvivsa.alalaaaletgsehpigkalvaaakar..sgal...tgfatfigrg........ayaigkpewltaldippd 85  
                  vvfDk+GTLt+g+  + ++ i s+  l+l   l  +++hpi + ++    +r  s      t++ + +g+g        ++  g+ +wl+       
  EEA22756.1  835 VVFDKTGTLTHGKlTVAVEHISSNdYLPLLISLIGSNKHPISASVATHLRGRgiS--AstvTDIKVHAGKGveglaqglTLRAGNSRWLNLS----- 924 
                  8************76666666666789999999999****************653..44479999999999*********************..... PP

                  HHHHHHHHHHHCHHHHHH..TTHHHHHHHHHHTHHBHTTHHHHHHHHHHTTEEEEEEESSEHHHHHHHHHHTTGGGESEEEEHHCES...STTTSHH CS
                  xxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxx RF
   Hydrolase   86 lgaaigsaqsqgrtvall..qaralavftiadplkvkpeaaeavasLkaagievvlltgdnpetaeraanqlGddyfdaviasdiet...vakpspe 177 
                   + +++s  +qg t++    ++ + avf ++d+  ++p+a e+v +L+++ i v +l+gd+  +++++a+qlG           i +    +   p 
  EEA22756.1  925 SDPQVQSVLEQGYTAFCFtiNDTLAAVFGLEDS--LRPDALETVTKLQERDISVHILSGDDDGPVHSIARQLG-----------IAAqnvRSRCTPI 1008
                  6666666777777666666699***********..**************************************...........4444458999*** PP

                  HHHHHHHHH..T.....ST.GGGEEEEESSHHHHHHHHH CS
                  xxxxxxxxx..x.....xx.xxxxxxxxxxxxxxxxxxx RF
   Hydrolase  178 gkvaaireL..q.....gk.peevamVGDgvnDaaalaa 208 
                  +k++ i+ L  q      k    +++VGDg nDa ala 
  EEA22756.1 1009 DKQRYIQTLvnQpghphKKiRTTTIFVGDGTNDAIALAS 1047
                  *********65377776334678**************96 PP

>> FA_hydroxylase  Fatty acid hydroxylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.5       0.5   2.3e+03      42      81 ..    1232    1273 ..    1208    1305 .. 0.56
   2 !   79.7  11.6   5.3e-26   2.4e-22       3     133 .]    1350    1475 ..    1348    1475 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.5
  FA_hydroxylase   42 laalrahplealllallllllllllgplsalll..vlvlaal 81  
                      +aa++    + l  ++l l+l+++l    +++l  +l+++++
      EEA22756.1 1232 WAASSSWRRDDLSRQALSLFLITWLFGVLMYFLgsTLLYHTI 1273
                      555555555555555444444444443333333333333333 PP

  == domain 2  score: 79.7 bits;  conditional E-value: 5.3e-26
  FA_hydroxylase    3 lallledfveYwvHrllHrvkllwrrlHkvHHsseaptalaalrahplealllallllllllllg.plsalllvlvlaallelliHsglhvsl 94  
                      l++l++d++ Y++HrllH+++ ++r +Hk HH+   pt++a+++++p++ + + l++ +  ll++ +  a+l ++v  + ++++iH +   ++
      EEA22756.1 1350 LFILFTDTGIYFIHRLLHHPS-IYRFIHKRHHKWIIPTPYASYAFNPVDGWAQSLPYHVFPLLFPlQKCAYLGLFVGVTGWTVFIHDA---EY 1438
                      799***************965.9999****************************77776666666366666668888999********...44 PP

  FA_hydroxylase   95 gwllerllatpraHrlHHskneegnfgvllslwDrlfgT 133 
                       +  ++ +++++ H +HH +++ +n+g+++++wDr++gT
      EEA22756.1 1439 LPY-SKAINGAACHTMHHLYFN-YNYGQFMTFWDRVCGT 1475
                      444.4569**************.***************9 PP

>> HMA  Heavy-metal-associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.1   0.1   4.5e-10     2e-06       2      61 ..     349     405 ..     348     406 .. 0.91
   2 ?   -3.3   0.0         3   1.3e+04      35      52 ..     448     465 ..     446     467 .. 0.72

  Alignments for each domain:
  == domain 1  score: 28.1 bits;  conditional E-value: 4.5e-10
         HMA   2 vrvsgmhCagCaakvekvLselpgVesvkvdlatktvtVegdaestklrkiieaiekagy 61 
                 ++vsg++C+gC+ k +++L +l++V++ k +l+ ++++++++ +      ++e ++ +g+
  EEA22756.1 349 LSVSGLTCTGCETKLKRALGSLQSVQNLKTSLVLSRAEFDLNCDV---QSLDEVLKHLGK 405
                 689**************************************9888...778888888776 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 3
         HMA  35 tktvtVegdaestklrki 52 
                  ++v+V++da  +  r++
  EEA22756.1 448 DQSVNVVYDAKIIGARDL 465
                 589999999987666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1499 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       853  (0.0475766); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.89u 0.31s 00:00:01.20 Elapsed: 00:00:00.60
# Mc/sec: 7510.74
//
Query:       EEA22757.1  [L=682]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    8.7e-09   34.8   0.1    1.7e-08   33.8   0.1    1.5  1  Fungal_trans  Fungal specific transcription factor domain
    2.3e-06   27.7   8.7    3.3e-05   24.1   3.3    3.2  2  zf-C2H2       Zinc finger, C2H2 type
    0.00026   21.0   3.3    0.00026   21.0   3.3    2.2  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
    0.00033   21.2   2.7    0.00033   21.2   2.7    3.5  2  zf-C2H2_4     C2H2-type zinc finger
  ------ inclusion threshold ------
       0.01   16.2  10.7       0.31   11.6   1.1    3.1  3  zf-H2C2_2     Zinc-finger double domain
      0.017   15.4   5.7       0.04   14.2   5.7    1.7  1  zf-Di19       Drought induced 19 protein (Di19), zinc-binding
       0.02   14.8   8.3       0.11   12.5   3.1    2.7  2  zf-C2HC_2     zinc-finger of a C2HC-type
       0.16   12.4   4.5        5.9    7.4   0.1    2.8  2  zf-met        Zinc-finger of C2H2 type
       0.32   10.8   4.1        1.3    8.9   4.1    2.1  1  zf-H2C2_5     C2H2-type zinc-finger domain
       0.33   11.3  11.6          4    7.8   0.8    2.6  2  zf-C2H2_jaz   Zinc-finger double-stranded RNA-binding
       0.35   10.9   5.4        8.7    6.5   0.2    2.9  2  zf-C2H2_6     C2H2-type zinc finger
        0.4   10.8   5.6        8.9    6.5   0.1    2.7  2  TRAF6_Z2      TNF receptor-associated factor 6 zinc finger 2
       0.63    9.7   4.0       0.36   10.5   0.9    1.9  2  DUF2225       Uncharacterized protein conserved in bacteria (
       0.81   10.2   6.0        5.6    7.5   1.6    2.7  2  Zn-C2H2_12    Autophagy receptor zinc finger-C2H2 domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.8   0.1   1.4e-11   1.7e-08       2     205 ..     317     521 ..     316     573 .. 0.80

  Alignments for each domain:
  == domain 1  score: 33.8 bits;  conditional E-value: 1.4e-11
  Fungal_trans   2 drffsnfhpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltses...qefiafplraeili.......hedfssps 88 
                     ff  +h ++p++h p+f+p             s+ lllai+  Ga ++   ++ +     s            + ++++          d  +  
    EEA22757.1 317 TAFFHSLHWHMPVVHCPTFDPAN----------VSNSLLLAIFLAGAVYTIPFQSADLVLPPSLLsvaE-----EYVFRKVAnlsatttPSDQPVRG 398
                   579********************..........*****************9888888887777664432.....22333333444556644444455 PP

  Fungal_trans  89 sslwilqsLlllelyektssdralher.....hhgvavrlarslgLhrnpsyvgkks.....lwklweeeaesrrRlwwaaFylDktialklGrppl 175
                   + ++++q+ l+le+  +  +d +l  r      h   v+  rs+gL r + +  +       + +l +  +e   R+++++F  D ++ +++ + p 
    EEA22757.1 399 YAIETVQAALILEMLQFSQGD-PLIRRririvRHPCLVSTIRSMGLFRYKRRQAPGVsdedkWRELAV--EEVCIRVACWTFLADGFLTVCFKNHPQ 492
                   66******************8.444444889889999999******9888887765588864444444..57777*********************9 PP

  Fungal_trans 176 lddsqinlpLPcddddlwesddaseetlve 205
                   l   ++++ +P + + l e++++s ++ + 
    EEA22757.1 493 LTILEMDCDFPWNTE-LFEAESVSSFNEMA 521
                   9**************.99999999998876 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   3.3   2.5e-08   3.3e-05       1      23 []      51      73 ..      51      73 .. 0.98
   2 ?    5.3   0.2     0.024        31       3      19 ..      81      97 ..      80     100 .. 0.83

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 2.5e-08
                EEETTTTEEESSHHHHHHHHHCC CS
     zf-C2H2  1 ykCpdCgksFkrksnLkrHirtH 23
                ++Cp C+ks++rks+L rH  tH
  EEA22757.1 51 FQCPQCDKSYSRKSHLLRHELTH 73
                89******************999 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.024
                ETTTTEEESSHHHHHHH CS
     zf-C2H2  3 CpdCgksFkrksnLkrH 19
                Cp+C+k F  ++  +rH
  EEA22757.1 81 CPICKKEFQKPEVARRH 97
                ********988877777 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0   3.3   2.1e-07   0.00026       2      34 ..     121     152 ..     120     157 .. 0.92

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 2.1e-07
                 S-HHHHHCT---ST.SSSS-HHHHHCTHHHCCCC CS
     Zn_clus   2 aCdnCrkkKvKCda.kkPaCsnCkklnleCtfys 34 
                 +Cd+C   K+ Cd+  +P C++C  l++ C+  +
  EEA22757.1 121 SCDSCFDAKTACDRsSIP-CGRCTGLGVRCS-LD 152
                 8*****************.***********9.65 PP

>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   2.7   2.6e-07   0.00033       1      23 [.      51      73 ..      51      74 .. 0.97
   2 ?    6.5   1.1     0.014        18       3      21 ..      81      99 ..      80     101 .. 0.77

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 2.6e-07
   zf-C2H2_4  1 fkCpiCgksFsskkaLlrHlkth 23
                f+Cp+C+ks+s+k++LlrH +th
  EEA22757.1 51 FQCPQCDKSYSRKSHLLRHELTH 73
                89********************9 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.014
   zf-C2H2_4  3 CpiCgksFsskkaL.lrHlk 21
                CpiC+k F  k ++ +rH k
  EEA22757.1 81 CPICKKEF-QKPEVaRRHSK 99
                ********.66665477977 PP

>> zf-H2C2_2  Zinc-finger double domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.1   0.00047       0.6      14      25 ..      50      61 ..      42      62 .. 0.80
   2 ?   11.6   1.1   0.00024      0.31       1      24 [.      65      88 ..      65      90 .. 0.94
   3 ?   -2.4   0.4       6.2     8e+03       7      11 ..     103     107 ..      95     127 .. 0.49

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00047
   zf-H2C2_2 14 pyeCplCdkaFk 25
                 ++Cp Cdk+++
  EEA22757.1 50 MFQCPQCDKSYS 61
                49********97 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 0.00024
   zf-H2C2_2  1 nLrrHirkHtgekpyeCplCdkaF 24
                +L rH  +Ht+e    Cp C+k F
  EEA22757.1 65 HLLRHELTHTSELSASCPICKKEF 88
                689*******************99 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 6.2
   zf-H2C2_2   7 rkHtg 11 
                 +kH +
  EEA22757.1 103 KKHNQ 107
                 45553 PP

>> zf-Di19  Drought induced 19 protein (Di19), zinc-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   5.7   3.2e-05      0.04       2      43 ..      50      90 ..      49     105 .. 0.75

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 3.2e-05
     zf-Di19  2 sftCPyCgk.eltvkeLveHvedeHrveskevvCPvCaekvtk 43
                 f+CP C k    ++ L++H  + H++e  ++ CP+C+++ +k
  EEA22757.1 50 MFQCPQCDKsYSRKSHLLRHELT-HTSEL-SASCPICKKEFQK 90
                69*******44666678888655.88765.689****988765 PP

>> zf-C2HC_2  zinc-finger of a C2HC-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   0.2     0.025        32       1      21 [.      49      70 ..      49      72 .. 0.81
   2 ?   12.5   3.1   8.4e-05      0.11       5      24 ..      81     101 ..      79     102 .. 0.96

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.025
   zf-C2HC_2  1 elvpCpkCgRsF.npdrlekHe 21
                e+ +Cp C  s+   + l +He
  EEA22757.1 49 EMFQCPQCDKSYsRKSHLLRHE 70
                799*****99987777777776 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 8.4e-05
   zf-C2HC_2   5 CpkCgRsF.npdrlekHepvC 24 
                 Cp+C+  F +p+   +H ++C
  EEA22757.1  81 CPICKKEFqKPEVARRHSKQC 101
                 ********************* PP

>> zf-met  Zinc-finger of C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5   0.8     0.019        24       1      20 [.      51      70 ..      51      73 .. 0.91
   2 ?    7.4   0.1    0.0046       5.9       3      19 ..      81      97 ..      80     100 .. 0.90

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.019
      zf-met  1 fyCelCnvtfnsesqlksHl 20
                f+C+ C+++++ +s+l  H 
  EEA22757.1 51 FQCPQCDKSYSRKSHLLRHE 70
                78999*************95 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.0046
      zf-met  3 CelCnvtfnsesqlksH 19
                C++C++ f+ + +++ H
  EEA22757.1 81 CPICKKEFQKPEVARRH 97
                ************99999 PP

>> zf-H2C2_5  C2H2-type zinc-finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.9   4.1   0.00098       1.3       1      25 [.      51      74 ..      51      75 .. 0.96

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00098
   zf-H2C2_5  1 YKCsqCDYstawksnLkRHlrrkHt 25
                ++C+qCD s ++ks L RH + +Ht
  EEA22757.1 51 FQCPQCDKSYSRKSHLLRHEL-THT 74
                89*****************99.998 PP

>> zf-C2H2_jaz  Zinc-finger double-stranded RNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   0.8    0.0031         4       2      23 ..      51      72 ..      50      73 .. 0.89
   2 ?    7.6   4.0    0.0038       4.9       4      26 ..      81     105 ..      80     106 .. 0.90

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.0031
                 CBBTTTTBBBSSHHHHHCCTTS CS
  zf-C2H2_jaz  2 fYCvlCdKyFksenaldnHlkS 23
                 f C+ CdK ++  + l  H+ +
   EEA22757.1 51 FQCPQCDKSYSRKSHLLRHELT 72
                 55*****************966 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0038
                  BTTTTBBBSSHHHHHCCTTS..HHH CS
  zf-C2H2_jaz   4 CvlCdKyFksenaldnHlkS..KkH 26 
                  C++C+K F++ ++ + H k   KkH
   EEA22757.1  81 CPICKKEFQKPEVARRHSKQcaKKH 105
                  *****************88888888 PP

>> zf-C2H2_6  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.2    0.0068       8.7       2      12 ..      51      61 ..      50      62 .. 0.90
   2 ?    5.4   1.0     0.015        19       4      12 ..      81      89 ..      80      90 .. 0.92

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0068
   zf-C2H2_6  2 heCsvCsksFp 12
                + C++C+ks++
  EEA22757.1 51 FQCPQCDKSYS 61
                89*******97 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.015
   zf-C2H2_6  4 CsvCsksFp 12
                C++C+k+F+
  EEA22757.1 81 CPICKKEFQ 89
                ********8 PP

>> TRAF6_Z2  TNF receptor-associated factor 6 zinc finger 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   0.1    0.0069       8.9       5      21 ..      52      69 ..      50      72 .. 0.78
   2 ?    5.0   1.8      0.02        26       5      18 ..      80      93 ..      78     101 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0069
    TRAF6_Z2  5 eCPQCQraF.QKnqlkeH 21
                 CPQC + +  K +l  H
  EEA22757.1 52 QCPQCDKSYsRKSHLLRH 69
                6****9998457787766 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.02
    TRAF6_Z2  5 eCPQCQraFQKnql 18
                 CP C + FQK  +
  EEA22757.1 80 SCPICKKEFQKPEV 93
                5**********766 PP

>> DUF2225  Uncharacterized protein conserved in bacteria (DUF2225)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.1      0.81     1e+03       4      19 ..      49      64 ..      47      69 .. 0.81
   2 ?   10.5   0.9   0.00028      0.36       5      28 ..      78     101 ..      74     111 .. 0.83

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.81
     DUF2225  4 kkieCPvCeekfkkkk 19
                +  +CP C++ + +k+
  EEA22757.1 49 EMFQCPQCDKSYSRKS 64
                5679*****9998875 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00028
     DUF2225   5 kieCPvCeekfkkkkvkssslrli 28 
                 + +CP+C+++f+k +v  ++ +  
  EEA22757.1  78 SASCPICKKEFQKPEVARRHSKQC 101
                 578*************99998865 PP

>> Zn-C2H2_12  Autophagy receptor zinc finger-C2H2 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.0   0.2     0.054        69       3      12 ..      53      62 ..      52      73 .. 0.80
   2 ?    7.5   1.6    0.0044       5.6       3      12 ..      81      90 ..      80      92 .. 0.93

  Alignments for each domain:
  == domain 1  score: 4.0 bits;  conditional E-value: 0.054
  Zn-C2H2_12  3 CPlCseqFpk 12
                CP C+++++ 
  EEA22757.1 53 CPQCDKSYSR 62
                ********97 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0044
  Zn-C2H2_12  3 CPlCseqFpk 12
                CP+C++ F+k
  EEA22757.1 81 CPICKKEFQK 90
                ********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (682 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       590  (0.0329076); expected 358.6 (0.02)
Passed bias filter:                      349  (0.0194657); expected 358.6 (0.02)
Passed Vit filter:                        67  (0.00373696); expected 17.9 (0.001)
Passed Fwd filter:                        20  (0.00111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.59u 0.30s 00:00:00.88 Elapsed: 00:00:00.46
# Mc/sec: 4484.73
//
Query:       EEA22758.1  [L=816]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    7.3e-40  136.1  16.4    7.3e-40  136.1  16.4    3.5  4  Eisosome1  Eisosome protein 1


Domain annotation for each model (and alignments):
>> Eisosome1  Eisosome protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.0   0.2      0.92   1.7e+04       7      26 ..      27      46 ..      25      62 .. 0.59
   2 ?   -1.9   0.1      0.21   3.8e+03      69      83 ..     188     202 ..     184     250 .. 0.71
   3 ?   -0.2   0.1     0.064   1.1e+03       3      34 ..     287     311 ..     286     365 .. 0.71
   4 !  136.1  16.4   4.1e-44   7.3e-40       1     124 [.     375     497 ..     375     498 .. 0.98

  Alignments for each domain:
  == domain 1  score: -4.0 bits;  conditional E-value: 0.92
   Eisosome1  7 aArrnvkaqLedidekvyad 26
                 A++ + a+L   ++k++a 
  EEA22758.1 27 LANASAAASLAHANQKTTAA 46
                56666666666666666655 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.21
   Eisosome1  69 mdqeevdaiAarrvq 83 
                 m+ + +++iA+++vq
  EEA22758.1 188 MEAARIHHIARTNVQ 202
                 777889999999988 PP

  == domain 3  score: -0.2 bits;  conditional E-value: 0.064
   Eisosome1   3 allaaArrnvkaqLedidekvyadtgkvspsl 34 
                 +l +aA++ + ++L ++ ++ + +       +
  EEA22758.1 287 NLHEAAQKLAAEKLAKMPRNELYN-------Q 311
                 688999999999999998876655.......2 PP

  == domain 4  score: 136.1 bits;  conditional E-value: 4.1e-44
   Eisosome1   1 reallaaArrnvkaqLedidekvyadtgkvspslneewerkakaaaqaradkrseneagkvdiGggkfmdqeevdaiAarrvqPvLdeInekaekeRer 99 
                 r+ l++ Ar+nv+a ++d+dekvyadtg++sps+++ewe+ka+ +a++++++rs+n  g++ +Gg+k+mdq+ev+aiA++r+qP+LdeI++++e++R+r
  EEA22758.1 375 RADLMEIARKNVHAAIQDMDEKVYADTGRPSPSMQREWEEKAQLRAKQESETRSTN-VGMIAVGGDKYMDQAEVEAIARARIQPTLDEIDDRVEEQRAR 472
                 678*****************************************************.****************************************** PP

   Eisosome1 100 daelkleeeekkreaeeekarerek 124
                 + e+kle+e+k+r+ e  +are+++
  EEA22758.1 473 EVEEKLEQERKQRRVETDRAREEQI 497
                 **********************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (816 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1868  (0.104189); expected 358.6 (0.02)
Passed bias filter:                      497  (0.0277205); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.83u 0.35s 00:00:01.18 Elapsed: 00:00:00.51
# Mc/sec: 4850.71
//
Query:       EEA22759.1  [L=566]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.6e-35  120.7  19.2    6.6e-35  120.7  19.2    2.0  2  MFS_1            Major Facilitator Superfamily
    2.1e-06   26.9  33.9    6.6e-06   25.2   3.7    4.5  4  Sugar_tr         Sugar (and other) transporter
  ------ inclusion threshold ------
          5    7.6   6.7         13    6.3   0.1    2.8  3  Phage_holin_3_1  Phage holin family (Lysis protein S)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  120.7  19.2   1.1e-38   6.6e-35       6     322 ..      79     481 ..      74     490 .. 0.78
   2 ?   -1.4   2.5      0.14   8.6e+02     254     292 ..     505     541 ..     486     555 .. 0.48

  Alignments for each domain:
  == domain 1  score: 120.7 bits;  conditional E-value: 1.1e-38
       MFS_1   6 flsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfasslw.lllvlrvlqGlgagal 102
                 +++++++s +++a + ++a  +  + +++ ll++   lg ++a ++  + +  +G r ++++g +l++++ ++++  +++ w  l+++rv+qG++ + +
  EEA22759.1  79 AVICATMSPIMAANTVTIALVFRKDFTQVALLTGYHLLGVGLAGILCVPTARIWGKRHLFIIGNVLMIVStAWAGG-STGNWrSLVAARVFQGFALAPF 176
                 444455555555555577777888888*******************************************444444.488999**************** PP

       MFS_1 103 fpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee............. 188
                  ++++a + d+f   erg+ +++ +++   Ga l+p++ g +++ lgW+++fy++ai+++ a+ ++++++pe++ +r+++   + +             
  EEA22759.1 177 EALVNACVGDLFFMHERGKRMAFSNVALFGGAFLTPVVVGKMTATLGWQWSFYFVAIFTAAALPFVFFFVPETAYRRAKNLNMDYSsddstddghgsqt 275
                 **************************************************************7775566655555555555555559999999999999 PP

       MFS_1 189 ......................................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllply 233
                                                                       +   +  l+p + ++l++  lw++l+  +l+++ +++ ++l  ++
  EEA22759.1 276 ditdstsrspgnnsesvqekphppepenevtsnttnaqysywrtlrlfngrktdENFLKLFLRP-FPLFLHPGILWACLTQGVLIGWTVFIGVVLAAVF 373
                 9999999999999999888888888888888888888888777777777666655555555555.9999999999955555555555555555555555 PP

       MFS_1 234 lqevlgls....glllaglllallalvgailallagrlsdr............lgrrrrlllallllllaalglallavt....ssavllll....vlv 308
                 l   l ++    g+l++g    +++++g+++   +g lsd             + +++r++l ++ ll++ +gl+ ++ t    + + +l+     ++v
  EEA22759.1 374 LGPPLWFDqvktGYLYTG--AFVGSILGLVF---SGLLSDWinkrmiklnkgtYEPEFRIILVFFQLLFSGIGLYGFGITaenvKRYGWLIPdvffAFV 467
                 566666665555588888..77777777544...5555555333688888888888************************9988777777777655666 PP

       MFS_1 309 liGfglgfvfpsll 322
                 ++G+ +g v++sl 
  EEA22759.1 468 VMGMVMGAVSSSLY 481
                 67887777655543 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.14
       MFS_1 254 alvgailallagrlsdrlgrrrrlllallllllaalgla 292
                 +++  +  +   +l+ + g+r + l ++++ + ++l+ +
  EEA22759.1 505 SFILTF--FAYDWLVVKAGSRAPFLAIGSIQVGICLLAI 541
                 222222..2333444444444444444444444443333 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   5.5   7.3e-06     0.044      47     116 ..     106     173 ..      81     182 .. 0.89
   2 !   25.2   3.7   1.1e-09   6.6e-06     374     449 ..     183     258 ..     176     261 .. 0.92
   3 !    3.7   0.0    0.0037        22      44      77 ..     381     414 ..     303     421 .. 0.67
   4 ?    1.8   1.4     0.014        83     299     341 ..     504     546 ..     490     559 .. 0.68

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 7.3e-06
                 HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHH CS
    Sugar_tr  47 lsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigv 116
                 ++ l+++  l+G  + +++  + + ++G++  ++i++vl++++++  + ++   ++  l+++Rv+ G+++
  EEA22759.1 106 QVALLTGYHLLGVGLAGILCVPTARIWGKRHLFIIGNVLMIVSTAWAGGST--GNWRSLVAARVFQGFAL 173
                 6678888899999999999999*****************************..67*************86 PP

  == domain 2  score: 25.2 bits;  conditional E-value: 1.1e-09
                 HHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCG CS
    Sugar_tr 374 lvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeie 449
                  v +lf ++ R+k +a++ ++ +   fl+ ++   +t ++g  ++f++ a++ ++++ fvfffvpet+ r  + ++
  EEA22759.1 183 CVGDLFFMHERGKRMAFSNVALFGGAFLTPVVVGKMTATLGWQWSFYFVAIFTAAALPFVFFFVPETAYRRAKNLN 258
                 57899**************************************************************998776655 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.0037
                 ...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHH CS
    Sugar_tr  44 ssvlsglivsiflvGaiiGslfagllgdrfGRkk 77 
                  +v +g +   ++vG+i+G +f+gll+d++ ++ 
  EEA22759.1 381 DQVKTGYLYTGAFVGSILGLVFSGLLSDWINKRM 414
                 6678888888899****************98876 PP

  == domain 4  score: 1.8 bits;  conditional E-value: 0.014
                 HHHHHHHHHH.HHHHHS-SH.HHHHHHHHHHHHHHHHHH..HHHH CS
    Sugar_tr 299 vnfvatfvai.flvdrfGRR.tllllGaagmaicfvilgivalll 341
                   f+ tf+a  +lv ++G R ++l +G++   ic++ +  ++++l
  EEA22759.1 504 FSFILTFFAYdWLVVKAGSRaPFLAIGSIQVGICLLAI--PMYIL 546
                 56899999955777777766155556666666666655..44443 PP

>> Phage_holin_3_1  Phage holin family (Lysis protein S)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.1       2.8   1.7e+04      49      58 ..      79      88 ..      75     107 .. 0.64
   2 ?    6.3   0.1    0.0022        13       6      63 ..     349     406 ..     345     415 .. 0.92
   3 ?    4.2   0.5      0.01        60      23      69 ..     466     513 ..     457     535 .. 0.73

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 2.8
  Phage_holin_3_1 49 allCgllala 58
                     a++C++++  
       EEA22759.1 79 AVICATMSPI 88
                     5666666533 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0022
  Phage_holin_3_1   6 lwaellawlqsaspqiiaavlAlviallrviYdgkswkkvlleallCgllalavrsll 63 
                      lwa l + +   +  +i++vlA+v+    +++d+ +       a++ ++l+l+ + ll
       EEA22759.1 349 LWACLTQGVLIGWTVFIGVVLAAVFLGPPLWFDQVKTGYLYTGAFVGSILGLVFSGLL 406
                      59999999999*****************************************999887 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.01
  Phage_holin_3_1  23 aavlAlvi.allrviYdgkswkkvlleallCgllalavrsllellglp 69 
                       +v+ +v+ a+  ++Y  ++ +++++ea+ C l+   + s +  + + 
       EEA22759.1 466 FVVMGMVMgAVSSSLYIVDAHRQIAVEAFTCMLFFKNIFSFILTFFAY 513
                      5677777746667889999************99877666665555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (566 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       711  (0.0396564); expected 358.6 (0.02)
Passed bias filter:                      283  (0.0157845); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.32s 00:00:00.97 Elapsed: 00:00:00.47
# Mc/sec: 3636.92
//
Query:       EEA22760.1  [L=498]
Description: MFS transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.6e-34  118.7  22.9    3.7e-34  118.2  22.9    1.1  1  MFS_1     Major Facilitator Superfamily
      1e-06   27.9  28.5    5.6e-06   25.5   3.7    3.7  4  Sugar_tr  Sugar (and other) transporter
      0.002   16.8   0.3      0.036   12.6   0.0    2.5  2  FPN1      Ferroportin1 (FPN1)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  118.2  22.9   6.3e-38   3.7e-34       6     324 ..      79     483 ..      74     495 .. 0.78

  Alignments for each domain:
  == domain 1  score: 118.2 bits;  conditional E-value: 6.3e-38
       MFS_1   6 flsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfasslw.lllvlrvlqGlgagal 102
                 +++++++s +++a + ++a  +  + +++ ll++   lg ++a ++  + +  +G r ++++g +l++++ ++++  +++ w  l+++rv+qG++ + +
  EEA22760.1  79 AVICATMSPIMAANTVTIALVFRKDFTQVALLTGYHLLGVGLAGILCVPTARIWGKRHLFIIGNVLMIVStAWAGG-STGNWrSLVAARVFQGFALAPF 176
                 444455555555555577777888888*******************************************444444.488999**************** PP

       MFS_1 103 fpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee............. 188
                  ++++a + d+f   erg+ +++ +++   Ga l+p++ g +++ lgW+++fy++ai+++ a+ ++++++pe++ +r+++   + +             
  EEA22760.1 177 EALVNACVGDLFFMHERGKRMAFSNVALFGGAFLTPVVVGKMTATLGWQWSFYFVAIFTAAALPFVFFFVPETAYRRAKNLNMDYSsddstddghgsqt 275
                 **************************************************************7775566655555555555555559999999999999 PP

       MFS_1 189 ......................................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllply 233
                                                                       +   +  l+p + ++l++  lw++l+  +l+++ +++ ++l  ++
  EEA22760.1 276 ditdstsrspgnnsesvqekphppepenevtsnttnaqysywrtlrlfngrktdENFLKLFLRP-FPLFLHPGILWACLTQGVLIGWTVFIGVVLAAVF 373
                 9999999999999999888888888888888888888888777777777666655555555555.9999999999955555555555555555555555 PP

       MFS_1 234 lqevlgls....glllaglllallalvgailallagrlsdr............lgrrrrlllallllllaalglallavt....ssavllll....vlv 308
                 l   l ++    g+l++g    +++++g+++   +g lsd             + +++r++l ++ ll++ +gl+ ++ t    + + +l+     ++v
  EEA22760.1 374 LGPPLWFDqvktGYLYTG--AFVGSILGLVF---SGLLSDWinkrmiklnkgtYEPEFRIILVFFQLLFSGIGLYGFGITaenvKRYGWLIPdvffAFV 467
                 566666665555588888..77777777544...5555555333688888888888************************9988777777777755666 PP

       MFS_1 309 liGfglgfvfpsllal 324
                 ++G+ +g v++sl  +
  EEA22760.1 468 VMGMVMGAVSSSLYIV 483
                 6888888777766554 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   3.7   2.2e-06     0.013      47     116 ..     106     173 ..     101     182 .. 0.90
   2 !   25.5   3.7   9.3e-10   5.6e-06     374     449 ..     183     258 ..     176     261 .. 0.92
   3 !    4.0   0.0     0.003        18      44      77 ..     381     414 ..     303     421 .. 0.67
   4 ?   -3.6   1.1      0.63   3.8e+03     395     432 ..     434     473 ..     424     482 .. 0.52

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 2.2e-06
                 HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHH CS
    Sugar_tr  47 lsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigv 116
                 ++ l+++  l+G  + +++  + + ++G++  ++i++vl++++++  + ++   ++  l+++Rv+ G+++
  EEA22760.1 106 QVALLTGYHLLGVGLAGILCVPTARIWGKRHLFIIGNVLMIVSTAWAGGST--GNWRSLVAARVFQGFAL 173
                 5677888888999999999999*****************************..67*************86 PP

  == domain 2  score: 25.5 bits;  conditional E-value: 9.3e-10
                 HHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCG CS
    Sugar_tr 374 lvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeie 449
                  v +lf ++ R+k +a++ ++ +   fl+ ++   +t ++g  ++f++ a++ ++++ fvfffvpet+ r  + ++
  EEA22760.1 183 CVGDLFFMHERGKRMAFSNVALFGGAFLTPVVVGKMTATLGWQWSFYFVAIFTAAALPFVFFFVPETAYRRAKNLN 258
                 57899**************************************************************998776655 PP

  == domain 3  score: 4.0 bits;  conditional E-value: 0.003
                 ...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHH CS
    Sugar_tr  44 ssvlsglivsiflvGaiiGslfagllgdrfGRkk 77 
                  +v +g +   ++vG+i+G +f+gll+d++ ++ 
  EEA22760.1 381 DQVKTGYLYTGAFVGSILGLVFSGLLSDWINKRM 414
                 6778888888899****************98876 PP

  == domain 4  score: -3.6 bits;  conditional E-value: 0.63
                 HHHHHHHHHHHHHHHHCHHH..T-HHHHHHHHHHHHHHHH CS
    Sugar_tr 395 nwlanflisllfpiiteaig..ggyvflvfaglavlfiif 432
                 + l++ +  + f i++e+++  g+ +  vf +++v+++++
  EEA22760.1 434 QLLFSGIGLYGFGITAENVKryGWLIPDVFFAFVVMGMVM 473
                 4555555555555555555544444444444444444433 PP

>> FPN1  Ferroportin1 (FPN1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.6   0.0     6e-06     0.036     164     228 ..     210     284 ..     206     320 .. 0.79
   2 ?    0.5   0.3      0.03   1.8e+02     267     301 ..     366     401 ..     359     416 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 6e-06
        FPN1 164 lapllvglllsfvslkiaigfilvvnlvsvvveyilla.kvYrkvpalaekeekkeeeeeeakee.........e 228
                 l p++vg ++++++++ +  f+++  ++++++ ++++  + Yr++ +l+ + +  ++ ++ + ++         +
  EEA22760.1 210 LTPVVVGKMTATLGWQWSFYFVAIFTAAALPFVFFFVPeTAYRRAKNLNMDYSSDDSTDDGHGSQtditdstsrS 284
                 89*******************************99996157********99999999888888844444433330 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.03
        FPN1 267 slalslLylt.VLsFdtlmtaylkseglsasvisll 301
                 ++ l+ ++l   L Fd + t+yl++  + +s+++l+
  EEA22760.1 366 GVVLAAVFLGpPLWFDQVKTGYLYTGAFVGSILGLV 401
                 67777788877899**************99999975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (498 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       785  (0.0437838); expected 358.6 (0.02)
Passed bias filter:                      375  (0.0209158); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.66u 0.31s 00:00:00.97 Elapsed: 00:00:00.49
# Mc/sec: 3086.22
//
Query:       EEA22761.1  [L=181]
Description: CFEM domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.5e-11   44.2  14.9    4.8e-11   42.6  14.9    1.9  1  CFEM      CFEM domain


Domain annotation for each model (and alignments):
>> CFEM  CFEM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.6  14.9   2.7e-15   4.8e-11       4      66 .]      25      84 ..      22      84 .. 0.93

  Alignments for each domain:
  == domain 1  score: 42.6 bits;  conditional E-value: 2.7e-15
                TS-GGGTCGGG---TTSS.S-TT-HHHHHH-HHHHHHHHHHHHHH--THHHHHHHHHHHHHHH CS
        CFEM  4 alPkCaqdClaeavkkssgCakddtaCiCtnaklqseitdCvtaaCtaeealaavnaasslCa 66
                alP Caq+C++++++   +C   d+ CiC+ +++++ +++Cv+ +C+a +++a++++a +lCa
  EEA22761.1 25 ALPPCAQACATNSIP-P-SC-GLDVRCICSATSFITGVSCCVATSCNAADQQATLQFAVQLCA 84
                89************6.4.48.789**************************************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1284  (0.0716158); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.44
# Mc/sec: 1229.66
//
Query:       EEA22762.1  [L=224]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.2e-53  180.3   1.9    2.7e-53  180.0   1.9    1.0  1  Ilm1             Increased loss of mitochondrial DNA protein 
     0.0057   15.9   0.4     0.0098   15.1   0.4    1.3  1  Choline_transpo  Plasma-membrane choline transporter


Domain annotation for each model (and alignments):
>> Ilm1  Increased loss of mitochondrial DNA protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  180.0   1.9     3e-57   2.7e-53       1     165 []       4     209 ..       4     209 .. 0.94

  Alignments for each domain:
  == domain 1  score: 180.0 bits;  conditional E-value: 3e-57
        Ilm1   1 iSsktlirslalfhltlavylltspeviadqelvyllgealridaarsfskpssplAflgvlLlvlalvDlvll....slneelavaeywgrq...... 89 
                 +Ssktli+++alf+++l+vyl+ sp++i+d+++++++gea++id ++++++ + plA++++lL+  alvDl+++    +++++l+++++ +r+      
  EEA22762.1   4 LSSKTLIQAHALFTFILSVYLVISPNAITDSDIIFIIGEAMQIDLDPAMTTFQYPLAICAILLTGEALVDLIIVrklpQIDDILSTVQHEQRRtedtgf 102
                 7**************************************************************************999999***999999999****** PP

        Ilm1  90 ..............................aplRlllffivslyiYlssesswlaakgasyaaavs.gvgleeLknrvvftfaflEmmfwfwvfvtLre 157
                                               a++R+++ff+vsl+iY+s  ++  a+ + s  +a + + gle++k+rvvft+af+Emmfw+w+++++re
  EEA22762.1 103 sritlqkpkqninaltiqlatlyneiwtfiACVRFCFFFAVSLFIYTSGGNAGKASLEWSDDDAGQiKLGLEQVKSRVVFTYAFVEMMFWLWTLSNVRE 201
                 ***********************************************999876664444444443469******************************* PP

        Ilm1 158 Errevlar 165
                 Errev++r
  EEA22762.1 202 ERREVATR 209
                 ****9987 PP

>> Choline_transpo  Plasma-membrane choline transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.4   1.1e-06    0.0098      39     115 ..     121     199 ..     104     204 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 1.1e-06
  Choline_transpo  39 pslllvplltllllllvsafwivvavalylassgestdkv......nsgsesglaavefessskvkalllyllfgllWtlefl 115
                      + +l   ++t+++++ +++f++v++   ++++sg++  k+       +  + +l+ +++  s+ v+ ++++ ++++lWtl  +
       EEA22762.1 121 LATLYNEIWTFIACVRFCFFFAVSL---FIYTSGGNAGKAslewsdDDAGQIKLGLEQV-KSRVVFTYAFVEMMFWLWTLSNV 199
                      5677778999999999999999988...7788999888889999973333333334455.45778888899999999998755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (224 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       588  (0.032796); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.42
# Mc/sec: 1613.77
//
Query:       EEA22763.1  [L=418]
Description: geranylgeranyl transferase beta subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.2e-30  103.2  11.9    7.1e-09   35.3   0.1    6.2  6  Prenyltrans      Prenyltransferase and squalene oxidase repea
    0.00016   20.9   0.0      0.087   11.9   0.0    3.1  2  SQHop_cyclase_C  Squalene-hopene cyclase C-terminal domain


Domain annotation for each model (and alignments):
>> Prenyltrans  Prenyltransferase and squalene oxidase repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.1   3.3e-07    0.0029       6      40 ..      63     112 ..      58     116 .. 0.70
   2 !   16.1   0.2   7.6e-07    0.0068       3      37 ..     124     164 ..     122     169 .. 0.93
   3 !   35.3   0.1   7.9e-13   7.1e-09       1      43 [.     184     226 ..     184     227 .. 0.97
   4 ?   -0.5   0.0      0.12   1.1e+03       4      16 ..     246     258 ..     243     259 .. 0.82
   5 !   16.1   0.1   7.6e-07    0.0068      19      43 ..     314     338 ..     311     339 .. 0.92
   6 !   21.3   0.0   1.8e-08   0.00016       1      43 [.     344     387 ..     344     388 .. 0.94

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 3.3e-07
                  HHHHHHHHSHTTS-BBSSTTS...............SBBHHHHHHHHHHH CS
  Prenyltrans   6 avefLlscQnedGGwggrpgs...............esdtyytywalaaL 40 
                   +++++ cQ+++GG++g  g                ++ + +t+ al++L
   EEA22763.1  63 YINWVYHCQHPQGGFRGFTGTkfgdanhtadnkawdPANVPATFLALQTL 112
                  589**************987666666666666666666666666666666 PP

  == domain 2  score: 16.1 bits;  conditional E-value: 7.6e-07
                  HHHHHHHHHHHSHTTS-BBSSTTS.......SBBHHHHHHHH CS
  Prenyltrans   3 vekavefLlscQnedGGwggrpgs.......esdtyytywal 37 
                  +++++++L + Q+ dG++g+  g+       + d++++y+a 
   EEA22763.1 124 RRECLQWLPKLQRNDGSFGDLLGVgekisggD-DLRFCYCAA 164
                  7899**************************88.*******95 PP

  == domain 3  score: 35.3 bits;  conditional E-value: 7.9e-13
                  HHHHHHHHHHHHHSHTTS-BBSSTTSSBBHHHHHHHHHHHHHC CS
  Prenyltrans   1 idvekavefLlscQnedGGwggrpgsesdtyytywalaaLall 43 
                  idv k+v ++ scQ +dGG+g+ p  e++++ ty+a+ aL ll
   EEA22763.1 184 IDVVKLVAYIQSCQSYDGGLGETPFREAHAGLTYCAMGALTLL 226
                  6999*************************************98 PP

  == domain 4  score: -0.5 bits;  conditional E-value: 0.12
                  HHHHHHHHHHSHT CS
  Prenyltrans   4 ekavefLlscQne 16 
                  ++++ +L s+Q  
   EEA22763.1 246 QSLLGWLVSRQTT 258
                  78999******75 PP

  == domain 5  score: 16.1 bits;  conditional E-value: 7.6e-07
                  -BBSSTTSSBBHHHHHHHHHHHHHC CS
  Prenyltrans  19 GwggrpgsesdtyytywalaaLall 43 
                  G++gr ++ +dt+y++w++ +L ++
   EEA22763.1 314 GFNGRLNKLADTCYCFWVTGTLGIM 338
                  9******************999665 PP

  == domain 6  score: 21.3 bits;  conditional E-value: 1.8e-08
                  HHHHHHHHHHHHHSH.TTS-BBSSTTSSBBHHHHHHHHHHHHHC CS
  Prenyltrans   1 idvekavefLlscQn.edGGwggrpgsesdtyytywalaaLall 43 
                  idv  ++ +Ll + +   GG+g + g  +d+y++y +l +Lal+
   EEA22763.1 344 IDVSGVRHYLLDKTQhIVGGFGKSVGEAPDLYHAYLGLISLALI 387
                  57788999**********************************98 PP

>> SQHop_cyclase_C  Squalene-hopene cyclase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.9   0.0   9.7e-06     0.087     182     227 ..      97     142 ..      44     152 .. 0.49
   2 !    3.9   0.0    0.0027        24     203     229 ..     180     206 ..     160     224 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 9.7e-06
                      SBSSHHHHHHHHHHHHHHTT--TTSHHHHHHHHHHHTT--TTSSBB CS
  SQHop_cyclase_C 182 WGvnyiyGtwsvlsalaavgedleepvirkavdWlksvqnedGGWG 227
                      W    +  t+ +l++l ++g dl++   r++++Wl + q++dG +G
       EEA22763.1  97 WDPANVPATFLALQTLLMLGDDLSRVKRRECLQWLPKLQRNDGSFG 142
                      2222333455555555555555555555555555555555555555 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.0027
                      -TTSHHHHHHHHHHHTT--TTSSBB-- CS
  SQHop_cyclase_C 203 dleepvirkavdWlksvqnedGGWGes 229
                      d ++  + k v++++s q  dGG Ge+
       EEA22763.1 180 DIRDIDVVKLVAYIQSCQSYDGGLGET 206
                      56666788999**************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (418 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       766  (0.0427241); expected 358.6 (0.02)
Passed bias filter:                      664  (0.037035); expected 358.6 (0.02)
Passed Vit filter:                        57  (0.00317921); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.31s 00:00:00.84 Elapsed: 00:00:00.42
# Mc/sec: 3002.71
//
Query:       EEA22764.1  [L=962]
Description: serine/threonine protein kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.2e-66  222.2   0.0    1.2e-65  221.5   0.0    1.4  1  Pkinase        Protein kinase domain
      2e-41  142.0   0.0    3.3e-41  141.3   0.0    1.3  1  Pkinase_Tyr    Protein tyrosine kinase
    1.7e-09   37.4   0.0    1.5e-08   34.3   0.0    2.0  2  Kinase-like    Kinase-like
    3.1e-06   26.4   0.1    3.1e-06   26.4   0.1    2.5  3  Haspin_kinase  Haspin like kinase domain
  ------ inclusion threshold ------
       0.08   12.0   0.0       0.13   11.3   0.0    1.2  1  Seadorna_VP7   Seadornavirus VP7
       0.13   12.1   2.0       0.76    9.6   0.2    2.5  3  APH            Phosphotransferase enzyme family
       0.16   11.5   0.2       0.26   10.8   0.2    1.2  1  Flp_C          Recombinase Flp protein
       0.21   11.5   0.4       0.51   10.3   0.4    1.6  1  Ferlin_C       Ferlin C-terminus


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  221.5   0.0   5.3e-69   1.2e-65       1     264 []      39     286 ..      39     286 .. 0.92

  Alignments for each domain:
  == domain 1  score: 221.5 bits;  conditional E-value: 5.3e-69
                 EEEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHSCTTB--EEEEEEESSEEEEEEE--TTEBHHHHHHHHSS--HHH CS
     Pkinase   1 yekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklkhpnivrlyevfeekdelylvleyveggeladllerkgslseee 99 
                 y+  + +G+GsfGkVy a++k t++    K++ k+++k+++  +++rEi+ ++++ hp+i rlyev+ +++ ++lvle+++g+el +++ ++g l+ ++
  EEA22764.1  39 YSLGRLIGKGSFGKVYLATHKLTNNS---KVVLKSSDKHDS--NLAREIHHHRQFLHPHIARLYEVIVTENLVWLVLEWCPGDELYNYILNNGPLPVDK 132
                 567899**************988874...666666655544..599***************************************************** PP

                 HHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTEEEE-SGTTSEESSSSCS.BCTTTSCGGGS-HHHHTTSCB.SHHHHHHHHHHHHHHHHHSS-S CS
     Pkinase 100 akkiakqilegleylHskgiiHrDlKpeNiLidekgelKitDFGlakelesssk.ltsfvgtseYlAPEvlkeney.skkvDvWslGvilyelltgkpp 196
                 +++i++q++ +++y+Hsk+++HrDlK eNiL+d++g++K++DFG+ +e+e + + l++f+gt  Y APE+lk+++y ++kvDvWslG+ily ll+g+ p
  EEA22764.1 133 VRRIFAQLVGAVAYVHSKSCVHRDLKLENILLDKHGNVKLCDFGFTREYEGKASyLQTFCGTICYSAPEMLKGEKYaGEKVDVWSLGIILYALLAGELP 231
                 ***************************************************99999***************999999********************** PP

                 TTTSSHHHHHHHHHHTHHHHHHHCTSHH...HHHTTS-HHHHHHHHHHT-SSGCCSTTHHHHHTSGGG CS
     Pkinase 197 fsgekgkekvekeldqlekilkilgetkeklpeaseiseeakdllkkllkkdpkkRltaeellqhpyl 264
                 + +++++e+++k+l++             +    ++++++ + l+k ll+k p  R+t +++l+hp+l
  EEA22764.1 232 YDEDDDQETKAKILKE-------------DPVFSDKFPDDSQALIKILLSKRPLLRPTLADILNHPFL 286
                 **77776655555555.............67788999*****************************97 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  141.3   0.0   1.5e-44   3.3e-41       3     257 ..      41     282 ..      39     283 .. 0.91

  Alignments for each domain:
  == domain 1  score: 141.3 bits;  conditional E-value: 1.5e-44
                  EEEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHTCTTTS CS
  Pkinase_Tyr   3 lgkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkklkhpnivkllgvctkeepllivteyvkgGdLlkfLrkkekekl 100
                  lg+ +G+G+fGkV+ +t k    +++ kV++K+ +     ++ ++l +e++  +++ hp+i +l+ v++ e+ +++v+e+++g +L +++ ++   +l
   EEA22764.1  41 LGRLIGKGSFGKVYLATHK---LTNNSKVVLKSSD-----KHDSNLAREIHHHRQFLHPHIARLYEVIVTENLVWLVLEWCPGDELYNYILNN--GPL 128
                  7899*************99...788899****983.....334579*********************************************98..9** PP

                  BHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEETTEEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSEEE.HHHHHHHHHHHHHH CS
  Pkinase_Tyr 101 tlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsenkvvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekkft.sksDvWsfGvllwE 197
                   ++++ ++ +q+  +++y++sk++vHrdl   N+Ll+++  vk++DfG +r+ e + +y ++      + + apE+lk +k+  +k DvWs G++l+ 
   EEA22764.1 129 PVDKVRRIFAQLVGAVAYVHSKSCVHRDLKLENILLDKHGNVKLCDFGFTREYEGKASYLQT--FCGTICYSAPEMLKGEKYAgEKVDVWSLGIILYA 224
                  *****************************************************777777655..456789*********9976489************ PP

                  HHTTSSGTTTTSHHHHHHHHHHTTEES-BBTTSBHHHHHHHHHHT-SSGGGS--HHHHHH CS
  Pkinase_Tyr 198 iftlgespypglkneevleklkegkrlekpekcpeelyelmkkcweedpeeRptfselve 257
                  ++  ge py + +++e+ +k+ ++  +   +k p++ + l+k  ++++p  Rpt++++++
   EEA22764.1 225 LLA-GELPYDEDDDQETKAKILKEDPVFS-DKFPDDSQALIKILLSKRPLLRPTLADILN 282
                  **9.********99999999977766654.5599999******************99975 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   0.0      0.16   3.5e+02      16      49 ..      41      74 ..      35      94 .. 0.76
   2 !   34.3   0.0   6.8e-12   1.5e-08     148     281 ..     136     267 ..     129     271 .. 0.78

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.16
  Kinase-like 16 rgellkkgdrsvvfevkdqetgeplavkvfllps 49
                  g l++kg +++v++++ + t+++ +v   + + 
   EEA22764.1 41 LGRLIGKGSFGKVYLATHKLTNNSKVVLKSSDKH 74
                 5789*****************9998887655444 PP

  == domain 2  score: 34.3 bits;  conditional E-value: 6.8e-12
  Kinase-like 148 llTlqlirlaanLqakglvhgkftvdnllldekgglmlggftaLvragtkvvl.seve..kgfaPpEllgsrggytrknktkmthkldaWqlGlviyr 242
                  +  +ql+  +a+ ++k  vh +++ +n+lld++g ++l +f+  + +  k+    + +    ++ pE+l    +y          k+d+W lG+  y 
   EEA22764.1 136 IF-AQLVGAVAYVHSKSCVHRDLKLENILLDKHGNVKLCDFGFTREYEGKASYlQTFCgtICYSAPEMLKG-EKY-------AGEKVDVWSLGIILYA 224
                  44.89***********************************9998888666665377776677999999876.233.......4579************ PP

  Kinase-like 243 iwclklPltlateeakeewkfkl....ckkipekvkaLlkkfL 281
                  + + +lP +++ ++  ++ ++k       k p+  +aL+k +L
   EEA22764.1 225 LLAGELPYDEDDDQETKAKILKEdpvfSDKFPDDSQALIKILL 267
                  *********9987766665555322213477777777777766 PP

>> Haspin_kinase  Haspin like kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       1.4   3.2e+03     108     129 ..      35      69 ..      10      71 .. 0.64
   2 !   26.4   0.1   1.4e-09   3.1e-06     205     265 ..     130     187 ..      76     191 .. 0.80
   3 ?   -6.9   6.9         8   1.8e+04       1      32 [.     645     681 ..     641     708 .. 0.62

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 1.4
  Haspin_kinase 108 d..........seklssevyqtke...kdkevvlK 129
                    +          +++++++vy +++   ++++vvlK
     EEA22764.1  35 SvgnyslgrliGKGSFGKVYLATHkltNNSKVVLK 69 
                    03444556666889999999999888888889988 PP

  == domain 2  score: 26.4 bits;  conditional E-value: 1.4e-09
  Haspin_kinase 205 wkqalsifwqivkiLyvaEtkfeFEHRdLhldniLvdknlnvtlidlklsRlessegkvly 265
                    ++++ +if q v  ++ + +k    HRdL+l+niL+dk++nv l+d+   R    egk++y
     EEA22764.1 130 VDKVRRIFAQLVGAVAYVHSKS-CVHRDLKLENILLDKHGNVKLCDFGFTREY--EGKASY 187
                    6789999999999999998885.56***********************99976..555555 PP

  == domain 3  score: -6.9 bits;  conditional E-value: 8
  Haspin_kinase   1 sssslsleslksrssqsslkhktshssLqkf......s 32 
                    sss++s++s+ +  s+s+ +  +s  s++ +      +
     EEA22764.1 645 SSSVSSVRSIHHAHSHSKASSISS-NSIDTMstptasT 681
                    567777777777777777764433.5666654444332 PP

>> Seadorna_VP7  Seadornavirus VP7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   5.8e-05      0.13     155     186 ..     145     174 ..     118     179 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 5.8e-05
  Seadorna_VP7 155 mdfhsestnllhGDcnpenlmcDknGylklvD 186
                     +h  s+ ++h D + en++ Dk G++kl D
    EEA22764.1 145 AYVH--SKSCVHRDLKLENILLDKHGNVKLCD 174
                   4556..789*********************99 PP

>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0     0.089     2e+02      23     106 ..      66     148 ..      48     151 .. 0.69
   2 ?    9.6   0.2   0.00034      0.76     165     195 ..     149     177 ..     130     179 .. 0.75
   3 ?   -2.7   0.1         2   4.4e+03      33      50 ..     360     377 ..     290     412 .. 0.73

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.089
                 EEEEEE-TTS-HHHHHHHHHHHHHHHHTT-B--B-CTTBS-EEETTEEEEEEE----EE-SS......HHHHHHHHHHHHHHHHHHCCHH CS
         APH  23 yvlrrnpparaaeeirrevallrlLakagvpvPevlagdtddeeigllfalieyvpgrsllr......klsaaqlpellealgeflaalh 106
                 +vl+ + +    + +r++++  ++L+ + ++  ev+      +e++ +++++e++pg  l++      +l  +  ++++++l+ + a +h
  EEA22764.1  66 VVLKSSDKH-DSNLAREIHHHRQFLHPHIARLYEVIV-----TENL-VWLVLEWCPGDELYNyilnngPLPVDKVRRIFAQLVGAVAYVH 148
                 555555555.666666777777777777335555555.....4444.8*************99887777777777777777776666555 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00034
                 -EEEE-SS-SGGGEEEC..TTEEEEE---TT CS
         APH 165 ptvllHgDlhpgNllvdpddgrvtGviDfed 195
                 +++ +H+Dl++ N+l+d++++    + Df++
  EEA22764.1 149 SKSCVHRDLKLENILLDKHGNVK--LCDFGF 177
                 67889************665555..778876 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 2
                 -HHHHHHHHHHHHHHHHT CS
         APH  33 aaeeirrevallrlLaka 50 
                   +e ++e+++lr L++a
  EEA22764.1 360 RRREKEAEARSLRRLSAA 377
                 344455555555555554 PP

>> Flp_C  Recombinase Flp protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.2   0.00012      0.26     132     210 ..       6      86 ..       2     102 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00012
       Flp_C 132 nkqeyqllkdnlvrsynkalkknapysifaikngpks.higrhlm.tsflsmkglteltnvvgnwsdkrasavarttythq 210
                  k e    k++lv syn  l+  +   + ++ n      ig+  +   +l+ + lt+ ++vv + sdk+ s +ar  + h+
  EEA22764.1   6 TKAEVLSQKEKLVNSYNELLQEFSSTDLRSVGNYSLGrLIGKGSFgKVYLATHKLTNNSKVVLKSSDKHDSNLAREIHHHR 86 
                 567777789****************999999997765158886552679**************************999886 PP

>> Ferlin_C  Ferlin C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.4   0.00023      0.51       8      41 ..     336     370 ..     331     406 .. 0.65

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00023
    Ferlin_C   8 akrlkGWWPliklkeq.ediereereakkkkKkkk 41 
                 +  l GWW l+  ke+ ++ +re+r ++k++  ++
  EEA22764.1 336 CDALAGWWALLIEKEErKEKKREKRRREKEAEARS 370
                 55789****98766541444455544444444333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (962 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1173  (0.0654247); expected 358.6 (0.02)
Passed bias filter:                      493  (0.0274974); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.81u 0.28s 00:00:01.09 Elapsed: 00:00:00.47
# Mc/sec: 6095.85
//
Query:       EEA22765.1  [L=1004]
Description: endoplasmic reticulum calcium ATPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.2e-52  177.2   6.5    3.6e-51  173.2   2.3    2.6  2  E1-E2_ATPase     E1-E2 ATPase
    9.8e-47  159.0   7.7      1e-46  159.0   6.2    1.8  2  Cation_ATPase_C  Cation transporting ATPase, C-terminus
    2.8e-22   80.0   0.6    3.1e-21   76.6   0.6    2.4  1  Hydrolase        haloacid dehalogenase-like hydrolase
    8.9e-19   67.0   0.1    2.3e-18   65.6   0.1    1.7  1  Cation_ATPase_N  Cation transporter/ATPase, N-terminus
    4.3e-17   62.0   0.0    8.3e-17   61.1   0.0    1.5  1  Cation_ATPase    Cation transport ATPase (P-type)
    3.9e-08   33.3   1.0    3.7e-06   26.9   0.8    2.5  2  Hydrolase_3      haloacid dehalogenase-like hydrolase
    1.7e-06   28.6   0.0    6.3e-06   26.7   0.0    2.0  2  HAD              haloacid dehalogenase-like hydrolase
  ------ inclusion threshold ------
      0.056   13.6   0.9       0.55   10.4   0.1    2.6  2  Fumarate_red_D   Fumarate reductase subunit D


Domain annotation for each model (and alignments):
>> E1-E2_ATPase  E1-E2 ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.3   0.1    0.0055        12     112     158 ..      51      97 ..      36     106 .. 0.79
   2 !  173.2   2.3   1.6e-54   3.6e-51       3     181 .]     122     325 ..     120     325 .. 0.97

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0055
                   HHHHHHHHHHHHHHHHHHHHHHHHS-STTTSSTTHHHHHHHHHHHHH CS
  E1-E2_ATPase 112 qkkldklgkvlvpvvlliallvflialllgkslaeallralallvaa 158
                   +  l+++  +lv++ l+ a++ f++al+ g++ ++a++   ++l++ 
    EEA22765.1  51 KLVLEQFQDQLVLILLASAAISFVLALFEGGDDWTAFVDPAVILTIL 97 
                   456889999*************************9999955555554 PP

  == domain 2  score: 173.2 bits;  conditional E-value: 1.6e-54
                   S--EEEEE-TTS-EEEEGGG--TTSEEEEETT-B--SEEEEEEE-S...EEE-TTTS---S-EE-.............G-TTEE-TT-EEEE-EEEE CS
  E1-E2_ATPase   3 lpptakvirdgteeeidakelvpGDivllkagdrvpaDgrivegsa...evdesaLTGEslpvek.............ekgdmvfsGtvvvsgeaka 83 
                   +++ +kv+r+gt+++ +++elvpGDi+ +  gdrvpaD+r+++ ++   +vd+++LTGEs+ v+k             ++++m+fsGt+vv+g+a+a
    EEA22765.1 122 SANVTKVVRNGTLQKLKSEELVPGDIIHIAVGDRVPADCRLLSIQSnsfRVDQAILTGESESVSKdtkvvpdkqavkqDQTNMLFSGTTVVAGHATA 218
                   678899***********************************9966666****************************999****************** PP

                   EEEE-TTTSTTTTTSTTS--------HHHHHHHHHHHHHHHHHHHHHHHHHHS-STTTSSTT.........HHHHHHHHHHHHHS-TTHHHHHHHHH CS
  E1-E2_ATPase  84 vVtatgedtelgkiarlveeakskktplqkkldklgkvlvpvvlliallvflialllgksla.........eallralallvaaiPcaLplavplal 171
                   +V+ tg +t +g i +++ ++ s+ tpl++kl+ +g vl++v+++i+++v+li++ +++++          ++l  a++l vaaiP++L+++++++l
    EEA22765.1 219 IVVLTGASTAIGGIHESITSQISEPTPLKQKLNDFGDVLAKVITVICIVVWLINIEHFNDPShggwakgaiYYLKIAVSLGVAAIPEGLAVVITTCL 315
                   ***********************************************************9999******9889999********************* PP

                   HHHHHHHHHT CS
  E1-E2_ATPase 172 algarrlakk 181
                   alg+r++a k
    EEA22765.1 316 ALGTRKMAAK 325
                   *******975 PP

>> Cation_ATPase_C  Cation transporting ATPase, C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.0       2.1   4.6e+03      60      80 ..     260     280 ..     239     302 .. 0.76
   2 !  159.0   6.2   4.5e-50     1e-46       1     182 []     777     980 ..     777     980 .. 0.92

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 2.1
  Cation_ATPase_C  60 lqalvtllvffltlllfgise 80 
                      ++++++++v+++++  f+  +
       EEA22765.1 260 VITVICIVVWLINIEHFNDPS 280
                      577788888877777665444 PP

  == domain 2  score: 159.0 bits;  conditional E-value: 4.5e-50
  Cation_ATPase_C   1 plplsaiqiLwinLvtDllpalaLaleppekdimkrpPrkkkepliskkmlrriliqgllqalvtllvffltlllfgisekenkls........ 86 
                      p +l ++q+Lw+nLvtD+lpa+aL+++pp+ d+m+rpPr+++e l+ + +l+r +++g++++++t++ + +++  f+   ++ ++         
       EEA22765.1 777 PEALIPVQLLWVNLVTDGLPATALSFNPPDHDVMRRPPRQRDEALVGGWLLFRYMVIGTYVGAATVFGYVWWFM-FNPAGPQISYWqlshfhkc 869
                      67899****************************************************************77776.4444433333246677778 PP

  Cation_ATPase_C  87 ................snyaqtmaFitlvlsqifnalnlrsrreslfkfsglfsnkllllaillslllqvlivyvpglnavfgtaplsleewli 164
                                      s++a+t+ + +lv+++++na+n+ s++esl++   l++n++l++ai+ls+ l+++i+y+p+l+ +f + pl+++ew+ 
       EEA22765.1 870 sasfpeigcsmfhndmSKSASTVSLSILVVIEMLNAMNALSSSESLLT-FPLWQNPMLVYAIILSMSLHFAILYIPFLQGLFAILPLDWNEWTA 962
                      88999999999999999*******************************.9999***************************************** PP

  Cation_ATPase_C 165 alllalvvllvdelvKll 182
                      +l++++ v+l+de++K++
       EEA22765.1 963 VLGISAPVILIDEILKYF 980
                      ****************97 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.6   0.6   1.4e-24   3.1e-21       3     210 .]     343     708 ..     341     708 .. 0.74

  Alignments for each domain:
  == domain 1  score: 76.6 bits;  conditional E-value: 1.4e-24
                 EEEEESBTTTBCHHHHHHHHHHHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHETTTE.................................. CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.................................. RF
   Hydrolase   3 tvvfDkdGTLttgepsvedvivsaalalaaaletgsehpigkalvaaakarsgaltgfatfigrg.................................. 67 
                 +++ Dk+GTLtt ++sve+v+            tg            ++++  + t fa  ig                                    
  EEA22765.1 343 VICSDKTGTLTTNQMSVERVLYLD--------STG----------QGFEEIDVEGTTFAP-IGALkkggkplkdlavssstirqmtevlslnneatlay 422
                 7999***************99999........333..........444444444444444.22112333333333333333333333333333333333 PP

                 ..........HHHHTHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHH..................................................... CS
                 ..........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..................................................... RF
   Hydrolase  68 ..........ayaigkpewltaldippdlgaaigsaqsqgrtvall..................................................... 103
                           +                          ++g   +l                                                      
  EEA22765.1 423 dpktgyscigE-------------------------PTEGALRVLAekigtdnaafnetvrslpasdalhatsryyekklplkatyefsrdrksmsvlv 496
                 33444223331.........................222222222244444444444444444444444477777778888888888888888888888 PP

                 ......................................................................................TTHHHHHHHHHHT CS
                 ......................................................................................xxxxxxxxxxxxx RF
   Hydrolase 104 ......................................................................................qaralavftiadp 116
                                                                                                       +  + +++ + dp
  EEA22765.1 497 gegknqkllvkgapesilercshvllgsdgprvpltkshigliseqvvecgnrglrvialaivsdistnpllhtaktseeyaqlerNLTLIGLVGMLDP 595
                 999999999**************************************************************************99999*********** PP

                 HHBHTTHHHHHHHHHHTTEEEEEEESSEHHHHHHHHHHTT..............GGGE.SEEEEHHCES......STTTSHHHHHHHHHHHTSTGGGEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..............xxxx.xxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase 117 lkvkpeaaeavasLkaagievvlltgdnpetaeraanqlG..............ddyf.daviasdiet......vakpspegkvaaireLqgkpeeva 194
                   ++pe+a  +++ ++agi+++++tgdn++tae++ +q+G               + f d ++++  e+      ++  +p +k ++++ Lq  ++ va
  EEA22765.1 596 --PRPEVASSIRKCREAGIRIIVITGDNRNTAESICRQIGvfgadenlqgksftGREFdDLTDSQKLEAvknaslFSRTEPAHKSKLVDLLQSLGHVVA 692
                 ..**************************************999988888766665555333333333336666777777*************99999** PP

                 EEESSHHHHHHHHHTT CS
                 xxxxxxxxxxxxxxxx RF
   Hydrolase 195 mVGDgvnDaaalaaAg 210
                 m GDgvnDa+al++A+
  EEA22765.1 693 MTGDGVNDAPALKKAD 708
                 **************98 PP

>> Cation_ATPase_N  Cation transporter/ATPase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.6   0.1     1e-21   2.3e-18       5      69 .]       8      72 ..       5      72 .. 0.97

  Alignments for each domain:
  == domain 1  score: 65.6 bits;  conditional E-value: 1e-21
  Cation_ATPase_N  5 sleevlekLetdlenGLtqaeaaerlkkyGpNelkekkkkslwvkllkqftnplvilLlvaalvs 69
                     s+ e+l+++++++e GLtq+++ ++++kyG+N+l+e++ ++lw+++l+qf++ lv++Ll++a++s
       EEA22765.1  8 SPAELLRDFGVSEEAGLTQDQVLRLREKYGSNALEEEEATPLWKLVLEQFQDQLVLILLASAAIS 72
                     6789***********************************************************98 PP

>> Cation_ATPase  Cation transport ATPase (P-type)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.1   0.0   3.7e-20   8.3e-17       2      91 .]     414     520 ..     413     520 .. 0.86

  Alignments for each domain:
  == domain 1  score: 61.1 bits;  conditional E-value: 3.7e-20
  Cation_ATPase   2 lcNsaafsensekdevkllGnktEsALlvlaeklgldteelree....................tkkvqeipFnssrKrmsvvlklepekkvrlyv 77 
                    l N+a++   ++k  ++++G++tE AL vlaek+g d+  ++e                      +  ++++F+++rK+msv++   + k+  l+v
     EEA22765.1 414 LNNEATL-AYDPKTGYSCIGEPTEGALRVLAEKIGTDNAAFNETvrslpasdalhatsryyekkLPLKATYEFSRDRKSMSVLVG--EGKNQKLLV 506
                    6789999.8899999*******************7777777777777777777777777774446667*****************..5699***** PP

  Cation_ATPase  78 KGApeiilkrCthv 91 
                    KGApe+il+rC+hv
     EEA22765.1 507 KGAPESILERCSHV 520
                    ************96 PP

>> Hydrolase_3  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.017        38      18      54 ..     598     634 ..     594     643 .. 0.89
   2 !   26.9   0.8   1.6e-09   3.7e-06     206     247 ..     691     732 ..     678     738 .. 0.87

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.017
                  HHHHHHHHHHHHTTSEEEEE-SS-HHHHHHHHHHCCC CS
  Hydrolase_3  18 ektkeaikklkekgikvviATGRslravlpvleelgl 54 
                  ++ ++ i+k++e+gi +++ TG +  +++++ +++g+
   EEA22765.1 598 PEVASSIRKCREAGIRIIVITGDNRNTAESICRQIGV 634
                  567789*******************999999998875 PP

  == domain 2  score: 26.9 bits;  conditional E-value: 1.6e-09
                  EEEEESSGGGHHHHHHSSEEEEETTS-HHHHHHSSEEE--GG CS
  Hydrolase_3 206 viafGDgeNDieMLeaaglgvAmgnaseevkkaAdyvtksnn 247
                  v+  GDg ND + L++a++gvAmg +++ +k aAd+v ++ n
   EEA22765.1 691 VAMTGDGVNDAPALKKADIGVAMGTGTDVAKLAADMVLADDN 732
                  5667*********************************98876 PP

>> HAD  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.7   0.0   2.8e-09   6.3e-06      87     188 .]     597     705 ..     567     705 .. 0.80
   2 ?   -2.5   0.0       2.5   5.7e+03     104     128 ..     755     781 ..     731     795 .. 0.82

  Alignments for each domain:
  == domain 1  score: 26.7 bits;  conditional E-value: 2.8e-09
         HAD  87 dpgalellaahraaGdrvvvvSgglrplvepllaelg...adevlatelevddrltgelglegkpvrgegkvaalre.wlaaegegidlee........ 173
                 +p++   ++++r+aG+r++v++g +r  +e ++++ g   ade l  +      +tg+   e ++  +++k+ a++   l+ + e+++ ++        
  EEA22765.1 597 RPEVASSIRKCREAGIRIIVITGDNRNTAESICRQIGvfgADENLQGK-----SFTGR---EFDDLTDSQKLEAVKNaSLFSRTEPAHKSKlvdllqsl 687
                 47999*****************************99955555555553.....99999...55666666999888887555555555555566677778 PP

         HAD 174 ..vvay.GDspsDlpllr 188
                   vva  GD+++D p+l+
  EEA22765.1 688 ghVVAMtGDGVNDAPALK 705
                 8788889********996 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 2.5
         HAD 104 vvvvSgglrplvepll.aelg.adevl 128
                  +++S+++ ++v ++l a+lg +++++
  EEA22765.1 755 RYLISSNIGEVVSIFLtAALGlPEALI 781
                 5899************99999766655 PP

>> Fumarate_red_D  Fumarate reductase subunit D
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.1   0.00025      0.55       9      56 ..      73     119 ..      68     129 .. 0.76
   2 ?    0.4   0.1       0.3   6.7e+02      13      45 ..     205     236 ..     198     277 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00025
  Fumarate_red_D   9 ifwlLFgaGGmvaAlvlpvlililglllplGlldsdalsyekvlafaq 56 
                     ++ +LF  G  ++A+v p++il + +l ++  ++++  s ek++a +q
      EEA22765.1  73 FVLALFEGGDDWTAFVDPAVILTILILNAIVGVSQE-SSAEKAIAALQ 119
                     5678******************99999887666655.55556655555 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.3
  Fumarate_red_D  13 LFgaGGmvaAlvlpvlililglllplGlldsda 45 
                     LF+ G++v A  + ++++++g   ++G ++++ 
      EEA22765.1 205 LFS-GTTVVAGHATAIVVLTGASTAIGGIHESI 236
                     564.88999999999999999999998876553 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1004 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       689  (0.0384294); expected 358.6 (0.02)
Passed bias filter:                      513  (0.0286129); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.77u 0.30s 00:00:01.07 Elapsed: 00:00:00.45
# Mc/sec: 6707.81
//
Query:       EEA22766.1  [L=274]
Description: 14-3-3 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   3.2e-103  344.0   2.0   4.5e-103  343.5   2.0    1.2  1  14-3-3    14-3-3 protein
  ------ inclusion threshold ------
      0.055   13.8   0.3        7.6    6.9   0.0    2.6  2  DUF1653   Protein of unknown function (DUF1653)


Domain annotation for each model (and alignments):
>> 14-3-3  14-3-3 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  343.5   2.0    5e-107  4.5e-103       1     222 []      14     232 ..      14     232 .. 0.99

  Alignments for each domain:
  == domain 1  score: 343.5 bits;  conditional E-value: 5e-107
                 HHHHHHHCCHHHHHHHHHCHHHHCSS---HCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCTCC.HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC CS
      14-3-3   1 laklaeqaeryddmveymkkvvelkeeLskeernlLsvayKnvvgarRaswrvlssieqkeeske.ekkvelikeyrekiekeLkeiceevlelldktl 98 
                 la+l+eqaeryd+mv+ymk     + eLs++ernlLsvayKnvvg+rRaswr++ssieqkeesk+ +++v++i++yr+kie+eL+++c++vl++ld+ l
  EEA22766.1  14 LARLCEQAERYDEMVTYMKL----NGELSVDERNLLSVAYKNVVGTRRASWRIISSIEQKEESKGsSEHVSIIRDYRQKIETELERVCQDVLDVLDESL 108
                 69****************97....99***************************************999******************************* PP

                 HCH.-SHHHHHHHHHHHHHHHHHHHCC--HHHHHHHHHHHHHHHHHHHHHHHTTTGCC-HHHHHHHHHHHHHHHCTT--HHHHHHHHHHHHHCCHCCCC CS
      14-3-3  99 ipkatseeskvfylkmkgDyyRYlaEfaegeekkeaaekakeaYeeAleiakkelqpthpirLglaLNySVflyeilnspekAcelakkafdeaiaeld 197
                 ipka+s eskvfy+kmkgDy+RYlaEfa+g+++k aa++a+eaY++A+++a++el+pthpirLglaLN+SVf+yeilnsp++Ac+lak+afd+aiaeld
  EEA22766.1 109 IPKAESGESKVFYHKMKGDYHRYLAEFASGNKRKVAATAAHEAYKNATDVAQTELTPTHPIRLGLALNFSVFYYEILNSPDRACHLAKQAFDDAIAELD 207
                 *99************************************************************************************************ PP

                 CS.TTTHHHHHHHHHHHHHHHHHHC CS
      14-3-3 198 elseesykdstlilqlLrdnltlWt 222
                 +lseesy+dstli+qlLrdnltlWt
  EEA22766.1 208 SLSEESYRDSTLIMQLLRDNLTLWT 232
                 ************************8 PP

>> DUF1653  Protein of unknown function (DUF1653)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.1    0.0058        52      17      37 ..      18      38 ..      11      61 .. 0.84
   2 ?    6.9   0.0   0.00085       7.6      20      48 ..     112     137 ..     104     146 .. 0.87

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.0058
     DUF1653 17 arhsEteeklVvYkalygdvk 37
                 + +E  +++V Y +l+g+ +
  EEA22766.1 18 CEQAERYDEMVTYMKLNGELS 38
                56788889*********9855 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.00085
     DUF1653  20 sEteeklVvYkalygdvklwvRpldmFle 48 
                 +E++e+ V Y++++gd   + R l+ F +
  EEA22766.1 112 AESGESKVFYHKMKGD---YHRYLAEFAS 137
                 7999************...9999999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (274 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       783  (0.0436723); expected 358.6 (0.02)
Passed bias filter:                      475  (0.0264934); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 2019.18
//
Query:       EEA22767.1  [L=271]
Description: eukaryotic translation initiation factor 3 subunit EifCj, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.3e-73  247.1  35.4    2.5e-73  246.9  35.4    1.0  1  eIF3_subunit   Translation initiation factor eIF3 subunit
  ------ inclusion threshold ------
        1.4    8.3  11.0        2.7    7.4  11.0    1.5  1  PBP_sp32       Proacrosin binding protein sp32
        1.5    8.4  14.6        0.3   10.6  10.6    1.7  2  VIR_N          Virilizer, N-terminal
        2.1    6.7   9.6        3.2    6.1   9.6    1.2  1  Cytomega_UL84  Cytomegalovirus UL84 protein
        5.1    7.1  34.4    1.5e+03   -0.9  34.4    2.1  1  YL1            YL1 nuclear protein
        5.2    6.7   9.2       0.53   10.0   4.4    1.7  2  Cupin_8        Cupin-like domain


Domain annotation for each model (and alignments):
>> eIF3_subunit  Translation initiation factor eIF3 subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  246.9  35.4   8.5e-77   2.5e-73       2     242 .]       4     271 .]       1     271 [] 0.90

  Alignments for each domain:
  == domain 1  score: 246.9 bits;  conditional E-value: 8.5e-77
  eIF3_subunit   2 sdWDdedfepssvakkpavaa..kWddEdededvkdswdaeeeeeeekekakkaaeakak..aakakkkkskkqkiaeke.errkaeeeeaeeeeel 93 
                   s+WDde+ + + ++++p+va   k+ddE++de v+dswda+e++e+e+ekak+aa+akak  aa+a+kkksk+q+i+e++ er+k eeee+e+++e 
    EEA22767.1   4 SKWDDEEDS-TPPSSPPPVAGrrKFDDEEDDE-VLDSWDAAEDSEVEREKAKAAAAAKAKadAAAAAKKKSKAQRIQEHQeERKKLEEEEEEDSDEY 98 
                   49***9973.3333344444468****99766.**********************99999**9*****************888888999999999** PP

  eIF3_subunit  94 eeedeaarkerlrkaeeesDlknaadlFGgv...................attketdlssldlfnpktkedFeelrkalaekltklekksphYssfl 171
                   + edea+r++rlrk+e++sDlk+a+dlFG++                   +t k+ dls+++lf+p+tk++F++l+++l+++lt+++ k+++Y+ ++
    EEA22767.1  99 SSEDEAERRARLRKTEKDSDLKHAEDLFGDIdlnrnrgkskaivvgdasdPT-KAIDLSAMPLFKPTTKDQFTALTNTLIPLLTANS-KKAQYALWA 193
                   ************************************************9665.**********************************.788****** PP

  eIF3_subunit 172 eelirdlakslssedikkvassltvlaneKqkeeKaaekggKkkkkakakts.......lkadteayddddddyDDFM 242
                    e++++l+k+l+s+++kkvas+lt+l+neK++ee++a+kggKk+k+ak+kts       +k+dt+ yd+dd   DDFM
    EEA22767.1 194 PEFAKQLVKDLPSDQVKKVASALTTLSNEKMREERQADKGGKKSKAAKTKTSlntardfTKVDTNVYDEDDLGDDDFM 271
                   ****************************************************55555555599999996664449**9 PP

>> PBP_sp32  Proacrosin binding protein sp32
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4  11.0   0.00092       2.7     166     239 ..      37     105 ..       9     108 .. 0.66

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.00092
    PBP_sp32 166 qpwperllnnveellksslslggkekapeakpkeeqllekkqeqleehkteekkkqeeqeeeekeeeakqeege 239
                 + w      +ve+  k++ +   k ka  a   +++    k ++++eh+ e+kk  ee eee+  e+++ +e+e
  EEA22767.1  37 DSWDAAEDSEVER-EKAKAAAAAKAKADAAAAAKKK---SKAQRIQEHQEERKK-LEEEEEEDSDEYSSEDEAE 105
                 5555555555554.2344444456666664444444...355689999877665.6666777778999888876 PP

>> VIR_N  Virilizer, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6  10.6    0.0001       0.3     129     237 ..       8     124 ..       3     148 .. 0.62
   2 ?   -0.9   0.1      0.35     1e+03     198     217 ..     220     238 ..     173     267 .. 0.50

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.0001
       VIR_N 129 edrvsipPppPapPvk.......elekedqynaspvrpeprePrtpelipaytgnvastpPpdddeeedaavpetve..eekeensekredyleeesPe 218
                 ++++s+pP+ P+p v        e ++e++   +  ++++ e ++++ ++a +++       +++++ +   ++ +e  + +ee++e  ++y+ e++ e
  EEA22767.1   8 DEEDSTPPSSPPP-VAgrrkfddEEDDEVLDSWDAAEDSEVEREKAKAAAAAKAKADAAAAAKKKSKAQRIQEHQEErkKLEEEEEEDSDEYSSEDEAE 105
                 4566766666554.455899974334444444456666666666776666666665444444444444333333333114445666678999999999* PP

       VIR_N 219 ertslkaeekdseaereer 237
                 +r++l++ ekds+ +++e+
  EEA22767.1 106 RRARLRKTEKDSDLKHAED 124
                 *************777766 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.35
       VIR_N 198 eeekeensekredyleeesP 217
                 + ++++++e++ d   ++s 
  EEA22767.1 220 S-NEKMREERQADKGGKKSK 238
                 2.222222222222222222 PP

>> Cytomega_UL84  Cytomegalovirus UL84 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   9.6    0.0011       3.2     141     204 ..      63     126 ..      51     131 .. 0.77

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0011
  Cytomega_UL84 141 esqtapatsqeeetaashepekkkekeekkeeededdrnddrergilcvvsnedsdvrpafslf 204
                    ++ +a     + +    h+ e+kk  ee  e+ de   +d+ er      +++dsd++ a  lf
     EEA22767.1  63 DAAAAAKKKSKAQRIQEHQEERKKLEEEEEEDSDEYSSEDEAERRARLRKTEKDSDLKHAEDLF 126
                    3333333333445567899999999999999999999**********************99998 PP

>> YL1  YL1 nuclear protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9  34.4      0.49   1.5e+03      52     166 ..      26     135 ..       5     257 .. 0.64

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.49
                 xxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxx RF
         YL1  52 dfdsdeedee..sdeeedeeegekelerqerkkrkkekkkrkaqkkkskkkkkkqkkkkkkkidpqakeprpkkks.eraswlpaeslltpkrRkssRa 147
                 +fd++e+de   s + ++++e e+e  +++ ++++k+   ++a+kkksk+++ +++++++k     + e+++++ s e++s+ +ae+  +++ Rk++++
  EEA22767.1  26 KFDDEEDDEVldSWDAAEDSEVEREKAKAAAAAKAKA-DAAAAAKKKSKAQRIQEHQEERK-----KLEEEEEEDSdEYSSEDEAER--RARLRKTEKD 116
                 5778887777665555555555553333333333111.11111222222222222222222.....112222222223333333322..2334556666 PP

                 xxxxxxxxxxxxxxxxxxx RF
         YL1 148 stvenkeqleerlkereer 166
                 s +++ e l+  +  +++r
  EEA22767.1 117 SDLKHAEDLFGDIDLNRNR 135
                 6666666665555555444 PP

>> Cupin_8  Cupin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   4.4   0.00018      0.53      42     128 ..      40     128 ..      22     153 .. 0.76
   2 ?   -1.2   0.2      0.44   1.3e+03      59      61 ..     223     225 ..     165     264 .. 0.48

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00018
     Cupin_8  42 ekaedvkvsvektpdgeadsf..keneelkfvkpeeeemtfkdfldelearrdtrsepyaylqnanlasefpelkedsdlpfateafgk 128
                 ++aed +v++ek + ++a +   +   + k+++++++ ++ ++  ++le++++++s++y +  +a+ ++ +++ ++dsdl++a+ +fg 
  EEA22767.1  40 DAAEDSEVEREKAKAAAAAKAkaDAAAAAKKKSKAQRIQEHQEERKKLEEEEEEDSDEYSSEDEAERRARLRKTEKDSDLKHAEDLFGD 128
                 456677777666665555554113333456666778899999999*******9999999999***********************9985 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.44
     Cupin_8  59 ads 61 
                 + +
  EEA22767.1 223 KMR 225
                 111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (271 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2732  (0.152379); expected 358.6 (0.02)
Passed bias filter:                      765  (0.0426683); expected 358.6 (0.02)
Passed Vit filter:                       178  (0.00992805); expected 17.9 (0.001)
Passed Fwd filter:                        50  (0.00278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.85u 0.33s 00:00:01.18 Elapsed: 00:00:00.48
# Mc/sec: 1704.17
//
Query:       EEA22768.1  [L=588]
Description: CTP synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   1.5e-121  404.7   0.3   1.9e-121  404.4   0.3    1.1  1  CTP_synth_N    CTP synthase N-terminus
    1.2e-54  185.0   0.0    2.9e-54  183.7   0.0    1.7  2  GATase         Glutamine amidotransferase class-I
    1.1e-06   28.5   0.2    4.3e-06   26.6   0.2    2.0  1  Peptidase_C26  Peptidase C26


Domain annotation for each model (and alignments):
>> CTP_synth_N  CTP synthase N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  404.4   0.3  3.2e-125  1.9e-121       1     265 []       2     274 ..       2     274 .. 0.98

  Alignments for each domain:
  == domain 1  score: 404.4 bits;  conditional E-value: 3.2e-125
                  EEEEEEE--STTTTHHHHHHHHHHHHHCTT--EEEEEEE-SSSSSSTT--CCCC--EEE-TT--EEETHHHHHHHHHT----GGGEEEHHHHHHHHHH CS
  CTP_synth_N   1 kyilvtGGvvSglGkGiiaaslgallksrglkvtlikiDPYlnvdagtlsplehGEvfvlddGaetDlDlGnYeRfldikltkennittGkiyksvie 98 
                  ky+lv+GGv+Sg+GkGiia+s+g llk+ gl+vt+ikiDPY+n+dagt+sp+ehGEv+v+ddG+e+DlDlGnYeR+l ++lt+++nittGkiy++vie
   EEA22768.1   2 KYVLVSGGVISGVGKGIIASSTGLLLKTIGLTVTSIKIDPYINIDAGTMSPIEHGEVYVTDDGGEMDLDLGNYERYLLTTLTRDHNITTGKIYQHVIE 99 
                  8************************************************************************************************* PP

                  HHHTTTTTT----CCCHHHHHHHHHHHHHH.H.C.....T-SEEEEEE-S-TTSGGGHHHHHHHHHHHHHH-TTTEEEEEEEE--B-..TTTSSB-HH CS
  CTP_synth_N  99 kerrGdylGktvqviphvtdeikeriekvakk.v.....eadvviveigGtvgdieslpfleairqlklelgkenvllihvtlvpvl..kaagelktk 188
                  ker G+ylGktvqv+ph+t++i+++ie+vak+ +     e+dv+i+e+gGtvgdies+pf++a++ql+ ++gk n+++ihv++vpv+     ge+ktk
   EEA22768.1 100 KERVGHYLGKTVQVVPHITNAIQDWIERVAKMpIdesgaEPDVCIIELGGTVGDIESAPFIHAVSQLQRRAGKGNYAQIHVSYVPVIppGPGGEQKTK 197
                  ******************************9854888877**********************************************9444689***** PP

                  HHHHHHHHHHHHT---SEEEEEESS---HHHHHHHHHHCT--GGGEEEEE--S-GGGHHHHHHHCTHHHHHHHHTT- CS
  CTP_synth_N 189 ptqhsvkelrslGiqpdiivcrsekeleeevkekialfcnvekeavisvkdvesiyevpllleeqglaelileklkl 265
                  ptq++v+++rs+G++pd+i+cr+e++le+++ +kia++c++e+++vi+v++v+++y+vpllle+q+l +++ e l+l
   EEA22768.1 198 PTQRAVSDVRSAGLNPDLIACRCEQPLEDSTIDKIANMCQMERKQVIAVHNVSTTYHVPLLLERQKLLKTLSELLNL 274
                  ************************************************************************99986 PP

>> GATase  Glutamine amidotransferase class-I
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.6   0.0      0.67     4e+03      47      68 ..     185     207 ..     184     211 .. 0.75
   2 !  183.7   0.0   4.9e-58   2.9e-54       2     188 ..     319     555 ..     318     557 .. 0.95

  Alignments for each domain:
  == domain 1  score: -2.6 bits;  conditional E-value: 0.67
                 EEEEESSCTT.TTTHHHHHHHHC CS
      GATase  47 lvsgGpgspg.vegkieaikear 68 
                 ++++Gpg  + ++ + +a++ +r
  EEA22768.1 185 VIPPGPGGEQkTKPTQRAVSDVR 207
                 79****99887777777776666 PP

  == domain 2  score: 183.7 bits;  conditional E-value: 4.9e-58
                 EEESSTSTHHHHHHHHHHTT-EEEEEETTSHHHHH.............HHTHHSTSEEEEEEESSCTTTTTHHHHHHHHCTSTS-EEEETHHHHHHHHH CS
      GATase   2 liDnydsvtenlvhalvelgvkvevvpidasaeei.............lellknpdgilvsgGpgspgvegkieaikearenkiPiLGICLGmQllaie 87 
                 l D+y s++++ +ha++ ++ k++v+++das++e              +++ +++dg++v+gG+g++++ g+++ai++ar++++P+LGICLGmQl++ie
  EEA22768.1 319 LHDAYISLSKSFEHAAMYCRKKLKVIWVDASHLEDetlevspaefhkaWHNVCTADGLCVPGGFGTRATLGMMKAITWARTKNVPFLGICLGMQLAVIE 417
                 78*****************************999999*****9987766679*********************************************** PP

                 TTTEEE......................EEECEEEEEEEEEEEETTT...........CGGTTTTSEEEEEEEEEEEEESG...CHHHTTEEEEEEEET CS
      GATase  88 fgrkvv......................kekekehhggtmrlgddet...........allyglknevierhrHryevnpk...elepaglevtaksed 150
                 ++r+v                       +e +k+++ggtmrlg++++           + lyg+ ++++erhrHryevnp+   +le+agl++++k+ +
  EEA22768.1 418 YARNVAgiedagseelhpdvnnhvivymPEVDKTKLGGTMRLGKHPCifqpgsewsklRALYGSAPQIQERHRHRYEVNPEmvdRLEKAGLTFVGKDIK 516
                 ***888888888888889999999999*9999*****************************************************************99 PP

                 TEEEEEEEEETT.T.EEEESSBTTSTTSTTHHHHHHHHHH CS
      GATase 151 deelmeiiekkn.p.fvgvQFHPEststpegpellfnfli 188
                 + e+meiie+k+ p fvgvQFHPE+ s+   p++   +++
  EEA22768.1 517 G-ERMEIIELKDhPwFVGVQFHPEYLSRVLSPSFTVLGFF 555
                 8.8*************************999988777665 PP

>> Peptidase_C26  Peptidase C26
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.6   0.2   7.3e-10   4.3e-06      99     216 .]     395     539 ..     385     539 .. 0.64

  Alignments for each domain:
  == domain 1  score: 26.6 bits;  conditional E-value: 7.3e-10
  Peptidase_C26  99 raalergvPilgiCrGlqllnvalGGtly..qdieeqsgltdhrehe...............qsaashavkvekgsl...laellgseeievnslH 174
                      a +++vP lgiC+G+ql  + +  +++  +d+ +++ + d  +h                    +h   +++gs    l  l+g +  +++  H
     EEA22768.1 395 TWARTKNVPFLGICLGMQLAVIEYARNVAgiEDAGSEELHPDVNNHVivympevdktklggtMRLGKHPCIFQPGSEwskLRALYG-SAPQIQERH 489
                    556789************98666554443112333333333343333665665555545443377899999998876111555566.555555555 PP

  Peptidase_C26 175 h..qaike......laeelrveAvae.DgviEaieseeakafvlgvQwHPE 216
                    +    ++          +l  +  +   + +E ie+++++ +++gvQ+HPE
     EEA22768.1 490 RhrYEVNPemvdrlEKAGLTFVGKDIkGERMEIIELKDHP-WFVGVQFHPE 539
                    511544436666644568999999985679********88.99*******9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (588 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       531  (0.0296168); expected 358.6 (0.02)
Passed bias filter:                      505  (0.0281667); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.28s 00:00:00.88 Elapsed: 00:00:00.42
# Mc/sec: 4216.67
//
Query:       EEA22769.1  [L=539]
Description: CTP synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.1e-93  312.5   0.0    2.7e-93  312.1   0.0    1.1  1  CTP_synth_N    CTP synthase N-terminus
    9.5e-55  185.3   0.0    2.4e-54  184.0   0.0    1.7  2  GATase         Glutamine amidotransferase class-I
      9e-07   28.9   0.2    3.6e-06   26.9   0.2    2.0  1  Peptidase_C26  Peptidase C26


Domain annotation for each model (and alignments):
>> CTP_synth_N  CTP synthase N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  312.1   0.0   4.5e-97   2.7e-93      49     265 .]       1     225 [.       1     225 [. 0.97

  Alignments for each domain:
  == domain 1  score: 312.1 bits;  conditional E-value: 4.5e-97
                  --CCCC--EEE-TT--EEETHHHHHHHHHT----GGGEEEHHHHHHHHHHHHHTTTTTT----CCCHHHHHHHHHHHHHH.H.C.....T-SEEEEEE CS
  CTP_synth_N  49 lsplehGEvfvlddGaetDlDlGnYeRfldikltkennittGkiyksviekerrGdylGktvqviphvtdeikeriekvakk.v.....eadvvivei 140
                  +sp+ehGEv+v+ddG+e+DlDlGnYeR+l ++lt+++nittGkiy++vieker G+ylGktvqv+ph+t++i+++ie+vak+ +     e+dv+i+e+
   EEA22769.1   1 MSPIEHGEVYVTDDGGEMDLDLGNYERYLLTTLTRDHNITTGKIYQHVIEKERVGHYLGKTVQVVPHITNAIQDWIERVAKMpIdesgaEPDVCIIEL 98 
                  9*******************************************************************************9854888877******** PP

                  -S-TTSGGGHHHHHHHHHHHHHH-TTTEEEEEEEE--B-..TTTSSB-HHHHHHHHHHHHHHT---SEEEEEESS---HHHHHHHHHHCT--GGGEEE CS
  CTP_synth_N 141 gGtvgdieslpfleairqlklelgkenvllihvtlvpvl..kaagelktkptqhsvkelrslGiqpdiivcrsekeleeevkekialfcnvekeavis 236
                  gGtvgdies+pf++a++ql+ ++gk n+++ihv++vpv+     ge+ktkptq++v+++rs+G++pd+i+cr+e++le+++ +kia++c++e+++vi+
   EEA22769.1  99 GGTVGDIESAPFIHAVSQLQRRAGKGNYAQIHVSYVPVIppGPGGEQKTKPTQRAVSDVRSAGLNPDLIACRCEQPLEDSTIDKIANMCQMERKQVIA 196
                  **************************************9444689***************************************************** PP

                  EE--S-GGGHHHHHHHCTHHHHHHHHTT- CS
  CTP_synth_N 237 vkdvesiyevpllleeqglaelileklkl 265
                  v++v+++y+vpllle+q+l +++ e l+l
   EEA22769.1 197 VHNVSTTYHVPLLLERQKLLKTLSELLNL 225
                  ************************99986 PP

>> GATase  Glutamine amidotransferase class-I
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0      0.57   3.4e+03      47      68 ..     136     158 ..     134     162 .. 0.76
   2 !  184.0   0.0     4e-58   2.4e-54       2     188 ..     270     506 ..     269     508 .. 0.95

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 0.57
                 EEEEESSCTT.TTTHHHHHHHHC CS
      GATase  47 lvsgGpgspg.vegkieaikear 68 
                 ++++Gpg  + ++ + +a++ +r
  EEA22769.1 136 VIPPGPGGEQkTKPTQRAVSDVR 158
                 79****99887777777776666 PP

  == domain 2  score: 184.0 bits;  conditional E-value: 4e-58
                 EEESSTSTHHHHHHHHHHTT-EEEEEETTSHHHHH.............HHTHHSTSEEEEEEESSCTTTTTHHHHHHHHCTSTS-EEEETHHHHHHHHH CS
      GATase   2 liDnydsvtenlvhalvelgvkvevvpidasaeei.............lellknpdgilvsgGpgspgvegkieaikearenkiPiLGICLGmQllaie 87 
                 l D+y s++++ +ha++ ++ k++v+++das++e              +++ +++dg++v+gG+g++++ g+++ai++ar++++P+LGICLGmQl++ie
  EEA22769.1 270 LHDAYISLSKSFEHAAMYCRKKLKVIWVDASHLEDetlevspaefhkaWHNVCTADGLCVPGGFGTRATLGMMKAITWARTKNVPFLGICLGMQLAVIE 368
                 78*****************************999999*****9987766679*********************************************** PP

                 TTTEEE......................EEECEEEEEEEEEEEETTT...........CGGTTTTSEEEEEEEEEEEEESG...CHHHTTEEEEEEEET CS
      GATase  88 fgrkvv......................kekekehhggtmrlgddet...........allyglknevierhrHryevnpk...elepaglevtaksed 150
                 ++r+v                       +e +k+++ggtmrlg++++           + lyg+ ++++erhrHryevnp+   +le+agl++++k+ +
  EEA22769.1 369 YARNVAgiedagseelhpdvnnhvivymPEVDKTKLGGTMRLGKHPCifqpgsewsklRALYGSAPQIQERHRHRYEVNPEmvdRLEKAGLTFVGKDIK 467
                 ***888888888888889999999999*9999*****************************************************************99 PP

                 TEEEEEEEEETT.T.EEEESSBTTSTTSTTHHHHHHHHHH CS
      GATase 151 deelmeiiekkn.p.fvgvQFHPEststpegpellfnfli 188
                 + e+meiie+k+ p fvgvQFHPE+ s+   p++   +++
  EEA22769.1 468 G-ERMEIIELKDhPwFVGVQFHPEYLSRVLSPSFTVLGFF 506
                 8.8*************************999998777665 PP

>> Peptidase_C26  Peptidase C26
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.9   0.2   6.1e-10   3.6e-06      99     216 .]     346     490 ..     336     490 .. 0.64

  Alignments for each domain:
  == domain 1  score: 26.9 bits;  conditional E-value: 6.1e-10
  Peptidase_C26  99 raalergvPilgiCrGlqllnvalGGtly..qdieeqsgltdhrehe...............qsaashavkvekgsl...laellgseeievnslH 174
                      a +++vP lgiC+G+ql  + +  +++  +d+ +++ + d  +h                    +h   +++gs    l  l+g +  +++  H
     EEA22769.1 346 TWARTKNVPFLGICLGMQLAVIEYARNVAgiEDAGSEELHPDVNNHVivympevdktklggtMRLGKHPCIFQPGSEwskLRALYG-SAPQIQERH 440
                    556789************98666554443112333333333343333665665555545443377899999998876111555566.555555555 PP

  Peptidase_C26 175 h..qaike......laeelrveAvae.DgviEaieseeakafvlgvQwHPE 216
                    +    ++          +l  +  +   + +E ie+++++ +++gvQ+HPE
     EEA22769.1 441 RhrYEVNPemvdrlEKAGLTFVGKDIkGERMEIIELKDHP-WFVGVQFHPE 490
                    511544436666644568999999985679********88.99*******9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (539 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       660  (0.0368119); expected 358.6 (0.02)
Passed bias filter:                      633  (0.0353059); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.60u 0.29s 00:00:00.88 Elapsed: 00:00:00.45
# Mc/sec: 3591.99
//
Query:       EEA22770.1  [L=438]
Description: enolase/allergen Asp F 22 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
   8.2e-153  507.9   0.0   1.1e-152  507.5   0.0    1.1  1  Enolase_C  Enolase, C-terminal TIM barrel domain
    1.1e-57  193.8   0.1    2.1e-57  192.9   0.1    1.5  1  Enolase_N  Enolase, N-terminal domain
      8e-05   22.3   0.0    0.00014   21.5   0.0    1.4  1  MR_MLE_C   Enolase C-terminal domain-like
  ------ inclusion threshold ------
      0.017   14.3   0.2        2.4    7.3   0.1    2.9  3  MAAL_C     Methylaspartate ammonia-lyase C-terminus


Domain annotation for each model (and alignments):
>> Enolase_C  Enolase, C-terminal TIM barrel domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  507.5   0.0  2.3e-156  1.1e-152       2     294 ..     144     434 ..     143     436 .. 0.99

  Alignments for each domain:
  == domain 1  score: 507.5 bits;  conditional E-value: 2.3e-156
                 -EE-EE-EEEEE-GGGSSSS--SSEEEEE-TT-SSHHHHHHHHHHHHHHHHHHHHHCC.GGGG-B-TTS-B----SSHHHHHHHHHHHHHHCT-TCTBE CS
   Enolase_C   2 lvlPvPalnvinGGshagnklalqefmilPvgassfkealrlGaevyhklksvlkkkygksatnvGdeGGfaPnlqsnkealdliveaiekaGykgkvk 100
                 +vlPvP++nv+nGGshag++la+qefmi+P  a++f+e lr+Gaevy+klks++kkkyg+sa+nvGdeGG+aP++q+++ealdli+eaie+aGy+gk+k
  EEA22770.1 144 YVLPVPFQNVLNGGSHAGGRLAFQEFMIVPDTAPTFSEGLRQGAEVYQKLKSLAKKKYGQSAGNVGDEGGVAPDIQTAEEALDLITEAIEQAGYTGKIK 242
                 79************************************************************************************************* PP

                 EEEE--GGGCEETCTTEEECTTTTTT..GGCEEEHHHHHHHHHHHHHHS-EEEEES-S-TT-HHHHHHHHHHHTTTSEEEESTTTTT-HHHHHHHHHCT CS
   Enolase_C 101 ialdvassefykekdkkydldfkeeesdkskkltseqladlykelvkkyPivsiedpldeddweawkklteelgdkvqivGddltvtnpkrlkeaiekk 199
                 ia+dvassefyk + kkydldfk++esd++k+lt+eqladlyk+l+kkyPivsiedp++eddweaw+++ ++ +  +qivGddltvtnp r+k+aie k
  EEA22770.1 243 IAMDVASSEFYKTDVKKYDLDFKNPESDPEKWLTYEQLADLYKNLAKKYPIVSIEDPFAEDDWEAWSYFYKTSD--FQIVGDDLTVTNPLRIKKAIELK 339
                 **************************************************************************..*********************** PP

                 --SEEEE-HHHH-SHHHHHHHHHHHHHTT-EEEEE--SC--S--HHHHHHHHCT-SEEE---S-SHHHHHHHHHHHHHHHHHGCC-EE-GGGCTT CS
   Enolase_C 200 aanalllkvnqiGsltesleavklakeagygvvvshrsGetedttiadlavglsaGqiktGaparserlakynqllrieeelgekakyaGkkvrk 294
                 ++nalllkvnqiG+ltes++a+k++++ g+gv+vshrsGeted+tiad++vgl+aGqiktGaparserlak+nq+lrieeelg++a+yaG+++r+
  EEA22770.1 340 SCNALLLKVNQIGTLTESIQAAKDSYAGGWGVMVSHRSGETEDVTIADIVVGLRAGQIKTGAPARSERLAKLNQILRIEEELGNNAIYAGENFRH 434
                 ********************************************************************************************987 PP

>> Enolase_N  Enolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  192.9   0.1   4.8e-61   2.1e-57       1     131 []       3     134 ..       3     134 .. 0.97

  Alignments for each domain:
  == domain 1  score: 192.9 bits;  conditional E-value: 4.8e-61
                 EEEEEEEEEE-TTS-EEEEEEEEETTC-EEEEE--B-BSSSSSS-B----SSTTSGGGT--HHHHHHHHHTHHHHHT..TSBTT-HHHHHHHHHHHH-S CS
   Enolase_N   1 IkkvkareildSrGnpTvevevttedgalgraavpsGaStgekealelrDgdkkrylgkgvekavenvnekiapali..gldvtdqeeiDkllielDgt 97 
                 I+k++ar ++dSrGnpTvev+v+te+g l ra+vpsGaStg++ea+elrDgdk++++gkgv+kav+nvn++i pa+i  ++dv+dq+++D++li+lDgt
  EEA22770.1   3 ISKIHARSVYDSRGNPTVEVDVVTETG-LHRAIVPSGASTGQHEACELRDGDKTKWGGKGVLKAVANVNDTIGPAIIkeNIDVKDQSKVDEFLIKLDGT 100
                 89**********************988.67**********************************************966699***************** PP

                 TT-TTT-HHHHHHHHHHHHHHHHHHHTS-HHHHH CS
   Enolase_N  98 enksklGaNailavSlAvakaaAkakelplyryl 131
                 +nk++lGaNail+vSlA+aka+A++k++ply ++
  EEA22770.1 101 PNKTNLGANAILGVSLAIAKAGAAEKGVPLYAHI 134
                 *******************************997 PP

>> MR_MLE_C  Enolase C-terminal domain-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.0   3.2e-08   0.00014      26     154 ..     220     373 ..     191     392 .. 0.80

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 3.2e-08
                 HHHHHHHHHHHHHHHHTTTSTSEEEEE-TTT.S.......................BHHHHHHHHHHHGG.GTESEEESSSSTTTHHHHHHHHHHHH.S CS
    MR_MLE_C  26 dvaedvervravreavgpgddvdlmvDanqa.w.......................dlatAirvarelee.ldllwlEEPvppeddleglaelrara.s 98 
                 + +e ++ ++++ e++g   ++++++D+  + +                       + ++   + + l++ + +  +E+P+   dd+e+     + + +
  EEA22770.1 220 TAEEALDLITEAIEQAGYTGKIKIAMDVASSeFyktdvkkydldfknpesdpekwlTYEQLADLYKNLAKkYPIVSIEDPFAE-DDWEAWSYFYK-TsD 316
                 56777777777777777777788888877774257777777888888888888888999999999***888***********9.78********5.559 PP

                 SEEEESTTSSS.HHHHHHHHHHTSESEEEEBHHHHTSHHHHHHHHHHHHHTT-EEEE CS
    MR_MLE_C  99 ipiaagEslys.radfrelleagavdivqpdvsrvgGitearkvaalaeafgvpvap 154
                  +i+++    + + ++++++e + + ++ ++v+++g +te+++ a+   a g+ v++
  EEA22770.1 317 FQIVGDDLTVTnPLRIKKAIELKSCNALLLKVNQIGTLTESIQAAKDSYAGGWGVMV 373
                 *****9965444*******************************99865555555443 PP

>> MAAL_C  Methylaspartate ammonia-lyase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0     0.018        81     180     218 ..      82     120 ..      75     127 .. 0.78
   2 ?    0.7   0.0     0.053   2.4e+02     102     142 ..     256     296 ..     249     307 .. 0.85
   3 ?    7.3   0.1   0.00053       2.4     137     214 ..     314     392 ..     309     401 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.018
      MAAL_C 180 ieavlyckekgvgaylGGscnetdvsarvsvhvalatrp 218
                 i+    +k  +  + l G+ n t+ +a+++  v+la+  
  EEA22770.1  82 IDVKDQSKVDEFLIKLDGTPNKTNLGANAILGVSLAIAK 120
                 55555566666777889******************9865 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.053
      MAAL_C 102 aaapyklliegPldagskeeqierlaelreklkekgikvel 142
                  ++ y+l + +P   ++k+   e+la l ++l++k   v++
  EEA22770.1 256 DVKKYDLDFKNPESDPEKWLTYEQLADLYKNLAKKYPIVSI 296
                 56789999**********************99998776665 PP

  == domain 3  score: 7.3 bits;  conditional E-value: 0.00053
      MAAL_C 137 gikvelvaDeWcntle.direfvdaeaadlvqiktPDlGginntieavlyckekgvgaylGGscnetdvsarvsvhval 214
                 +++ ++v D+ + t    i++ ++ ++++++ +k+  +G+++++i+a   +   g g+++   + et+  + + + v+l
  EEA22770.1 314 TSDFQIVGDDLTVTNPlRIKKAIELKSCNALLLKVNQIGTLTESIQAAKDSYAGGWGVMVSHRSGETEDVTIADIVVGL 392
                 567899999987765438****************************************999999999987666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (438 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       407  (0.0227007); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.50u 0.24s 00:00:00.74 Elapsed: 00:00:00.40
# Mc/sec: 3297.93
//
Query:       EEA22771.1  [L=393]
Description: proteasome regulatory particle subunit Rpt4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      6e-43  146.4   0.0    1.2e-42  145.5   0.0    1.5  1  AAA              ATPase family associated with various cellul
    5.4e-12   45.5   0.2    9.5e-11   41.5   0.0    2.5  2  Prot_ATP_ID_OB   Proteasomal ATPase OB C-terminal domain
    3.3e-11   42.8   0.1    7.4e-11   41.7   0.1    1.6  1  AAA_lid_3        AAA+ lid domain
    1.7e-07   31.8   0.0      6e-05   23.5   0.0    2.6  2  AAA_16           AAA ATPase domain
    1.5e-06   28.3   0.1    3.8e-05   23.7   0.1    2.8  1  AAA_5            AAA domain (dynein-related subfamily)
    2.7e-06   27.6   0.0    9.3e-06   25.9   0.0    1.9  1  AAA_2            AAA domain (Cdc48 subfamily)
    6.8e-06   25.9   0.0    1.5e-05   24.8   0.0    1.5  1  RuvB_N           Holliday junction DNA helicase RuvB P-loop d
    0.00021   21.6   0.1     0.0061   16.8   0.0    2.4  2  AAA_22           AAA domain
    0.00033   19.9   0.0    0.00066   18.9   0.0    1.5  1  DUF815           Protein of unknown function (DUF815)
    0.00037   21.1   0.5     0.0026   18.3   0.0    2.4  2  AAA_18           AAA domain
    0.00086   18.9   0.0     0.0018   17.8   0.0    1.5  1  AAA_7            P-loop containing dynein motor region
     0.0018   17.5   0.3     0.0042   16.3   0.0    1.7  2  TIP49            TIP49 P-loop domain
     0.0031   17.5   0.1     0.0089   16.0   0.0    1.8  1  TsaE             Threonylcarbamoyl adenosine biosynthesis pro
     0.0034   16.8   1.0       0.14   11.5   0.0    2.7  3  ATPase           KaiC
      0.004   17.3   0.0       0.01   16.0   0.0    1.8  1  AAA_33           AAA domain
     0.0042   16.7   0.0      0.012   15.2   0.0    1.7  1  Prot_ATP_OB_N    Proteasomal ATPase OB N-terminal domain
     0.0045   16.4   0.0     0.0086   15.5   0.0    1.4  1  Mg_chelatase     Magnesium chelatase, subunit ChlI
     0.0058   17.0   0.0      0.012   16.0   0.0    1.5  1  RNA_helicase     RNA helicase
     0.0059   16.4   0.0      0.012   15.4   0.0    1.4  1  IstB_IS21        IstB-like ATP binding protein
      0.006   16.6   0.0      0.016   15.2   0.0    1.7  1  AAA_14           AAA domain
     0.0076   16.0   0.1      0.058   13.1   0.0    2.2  2  AAA_24           AAA domain
     0.0084   15.8   0.0      0.031   14.0   0.0    1.9  2  Sigma54_activat  Sigma-54 interaction domain
  ------ inclusion threshold ------
       0.01   15.5   0.1        3.8    7.1   0.0    2.6  2  Thymidylate_kin  Thymidylate kinase
      0.012   15.4   0.0       0.03   14.2   0.0    1.6  1  AAA_3            ATPase family associated with various cellul
      0.042   13.6   0.0       0.11   12.2   0.0    1.6  1  AAA_30           AAA domain
      0.046   13.1   4.9      0.036   13.4   1.9    2.0  2  GAS              Growth-arrest specific micro-tubule binding
      0.056   13.2   0.4       0.26   11.0   0.0    2.0  2  AAA_11           AAA domain
      0.057   12.9   0.0       0.11   11.9   0.0    1.4  1  PhoH             PhoH-like protein
      0.058   13.3   0.1       0.15   12.0   0.0    1.7  2  NACHT            NACHT domain
      0.076   12.0   0.1       0.13   11.2   0.1    1.2  1  DUF3363          Protein of unknown function (DUF3363)
      0.088   13.0   0.0       0.17   12.1   0.0    1.5  1  AAA_28           AAA domain
      0.094   12.3   0.0       0.21   11.2   0.0    1.5  1  AAA_25           AAA domain
        0.1   12.9   0.1       0.26   11.6   0.1    1.9  1  AAA_19           AAA domain
       0.11   12.4   0.8       0.29   11.0   0.8    1.7  1  Sec8_exocyst     Sec8 exocyst complex component specific doma
       0.11   11.7   0.0       0.25   10.6   0.0    1.5  1  Zeta_toxin       Zeta toxin
       0.12   11.5   0.0        0.2   10.7   0.0    1.3  1  Parvo_NS1        Parvovirus non-structural protein NS1
        0.2   12.1   2.2       0.59   10.6   2.2    1.7  1  DUF16            Protein of unknown function DUF16
       0.35   11.3   3.5        1.1    9.6   0.8    2.8  2  DHHA1            DHHA1 domain


Domain annotation for each model (and alignments):
>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  145.5   0.0   2.6e-45   1.2e-42       1     132 []     174     307 ..     174     307 .. 0.96

  Alignments for each domain:
  == domain 1  score: 145.5 bits;  conditional E-value: 2.6e-45
                 EEEESSTTSSHHHHHHHHHHHHTHEEEEEETTTCSSSSTTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHH...TTCCCHHHHHHHHHHHHHHHHT CS
         AAA   1 vllyGppGtGKTllakavakelgvefleisgsellskyvgesekkirelfkeakekakpsilfiDEidalaksr...sgseseeeervvnqLlteldgv 96 
                 vllyGppGtGKTlla+ava++l+++fl++  s +++ky+ges++ ire+f  ake++ p+i+f+DEida++++r    +s+++e +r++ +Ll++ldg+
  EEA22771.1 174 VLLYGPPGTGKTLLARAVASSLETNFLKVVSSAIVDKYIGESARLIREMFGYAKEHE-PCIIFMDEIDAIGGRRfseGTSADREIQRTLMELLNQLDGF 271
                 79******************************************************8.****************986666888889************* PP

                 TTSSSTEEEEEEESSGGGSTHHHHS.TTSSEEEETTS CS
         AAA  97 kkkeskvivigatnrpdkldpallr.gRfdrkieiel 132
                 +   +k+ +i+atnrpd+ldpallr gR+drkiei+l
  EEA22771.1 272 DYL-GKTKIIMATNRPDTLDPALLRaGRLDRKIEIPL 307
                 **6.77****************************985 PP

>> Prot_ATP_ID_OB  Proteasomal ATPase OB C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.5   0.0     2e-13   9.5e-11       1      57 []      61     116 ..      61     116 .. 0.97
   2 ?    1.1   0.0      0.84     4e+02       6      38 ..     315     348 ..     314     349 .. 0.84

  Alignments for each domain:
  == domain 1  score: 41.5 bits;  conditional E-value: 2e-13
                     EEEEEEE-TTSSEEEEE-TTS-EEEEEE-GGGSSST--TTEEEEEETTTTEEEEEE- CS
  Prot_ATP_ID_OB   1 VatVsEvlddteraiVktssdeevvvslagavpremLrpgDlVavdkdtgfifEkLP 57 
                     +++V + ld+ er iVk ss+  +vv + ++v++++L++g++Va+d +t  i+  LP
      EEA22771.1  61 IGEVLKQLDE-ERFIVKASSGPRYVVGCRSKVDKAKLKQGTRVALDMTTLTIMRMLP 116
                     7899999***.******************************************9999 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.84
                     EE-TTSSEEEEE-TT..S-EEEEEE-GGGSSST-- CS
  Prot_ATP_ID_OB   6 EvlddteraiVktss..deevvvslagavpremLr 38 
                     E+l + + + V+t++  d e++v++++ ++ ++Lr
      EEA22771.1 315 EILKI-HASTVVTEGeiDFESIVKMSDGLNGADLR 348
                     88999.8888888664577********99999998 PP

>> AAA_lid_3  AAA+ lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.7   0.1   1.6e-13   7.4e-11       2      45 .]     330     373 ..     329     373 .. 0.97

  Alignments for each domain:
  == domain 1  score: 41.7 bits;  conditional E-value: 1.6e-13
   AAA_lid_3   2 vdlkeLAerTeGySGADlaalcreAallAlrrgikeitmedfee 45 
                 +d++ ++++++G  GADl +++ eA++ A+++ +++i+++df++
  EEA22771.1 330 IDFESIVKMSDGLNGADLRNVVTEAGFFAIKDERDSINQDDFNK 373
                 8*****************************************86 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   0.0   1.3e-07     6e-05      22      51 ..     169     198 ..     141     215 .. 0.82
   2 ?    5.6   0.0     0.039        18     121     163 ..     217     266 ..     203     274 .. 0.74

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 1.3e-07
      AAA_16  22 grpelvllsGesGvGKsslvrellralekd 51 
                   p  vll+G++G+GK+ l+r+++ +le++
  EEA22771.1 169 KPPKGVLLYGPPGTGKTLLARAVASSLETN 198
                 44599*******************999987 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.039
      AAA_16 121 ellkrllallsrderplvlvlDdlq........wadeaslqllaaLlrlle 163
                 +l+++++ ++++ ++p ++++D+++           +a++++ ++L++ll+
  EEA22771.1 217 RLIREMFGYAKE-HEPCIIFMDEIDaiggrrfsEGTSADREIQRTLMELLN 266
                 678888899999.888*********88887665333355555555555544 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.7   0.1   8.1e-08   3.8e-05       1     135 [.     173     294 ..     173     296 .. 0.78

  Alignments for each domain:
  == domain 1  score: 23.7 bits;  conditional E-value: 8.1e-08
                 EEEEE--SSSSHHHHHHHGGGGBS--EEEEE--TT--HHHHH--B--.........--------.G-SEEEEESGGG--HHHHHHHHHHHHSSEEE..- CS
       AAA_5   1 dvlLvGppGtgKselaerlaaalnreveyvqltrdtteedlkgrreikngttslvdsplvraar.egeilvlDEveraesevlnsLlslleerrlllee 98 
                 +vlL GppGtgK+ la+ +a+ l+++++ v  ++      ++ ++   ++ ++l    +  a + e++i+++DE++ +    +++  s   e ++ l+e
  EEA22771.1 173 GVLLYGPPGTGKTLLARAVASSLETNFLKVVSSA------IVDKYI--GESARLIREMFGYAKEhEPCIIFMDEIDAIGGRRFSEGTSADREIQRTLME 263
                 59************************99998776......666666..444455556666555579999999999999988888888888888888888 PP

                 SSSEEE---......-EEEEEESS--.-TT-TTHHHH CS
       AAA_5  99 ggelvkaknddllerfrviatanpldrslnelspalr 135
                 + ++ +   +  l ++ +i+++n++d     l+pal+
  EEA22771.1 264 LLNQLDGFDY--LGKTKIIMATNRPD----TLDPALL 294
                 8777766554..45588999999988....7777776 PP

>> AAA_2  AAA domain (Cdc48 subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.9   0.0     2e-08   9.3e-06       6     104 ..     174     266 ..     169     281 .. 0.83

  Alignments for each domain:
  == domain 1  score: 25.9 bits;  conditional E-value: 2e-08
                 EEEE--TTSSHHHHHHHHHHHTT-....-EEEEEGGG-------THHHHHHHHHTTT-HHHHTTSEEEEETGGG-------------HHHHHHHHHHHH CS
       AAA_2   6 illlgptgvGktelakalaellfvkkekkliradaselleeeevehlvsrligappgyvgaeegGivllDEidKihpkessgadvSregVqrdLLqile 104
                 +ll gp g+Gkt+la+a+a+ l+     ++  +  s++    +     +rli +  gy +  e  i+++DEid i  ++ s+      ++qr L+ +l 
  EEA22771.1 174 VLLYGPPGTGKTLLARAVASSLET----NFLKVVSSAIVD--KYIGESARLIREMFGYAKEHEPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLN 266
                 6899******************95....677766676666..33444579999999*********************755555555679***9999986 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.8   0.0   3.1e-08   1.5e-05      35      94 ..     173     240 ..     164     247 .. 0.76

  Alignments for each domain:
  == domain 1  score: 24.8 bits;  conditional E-value: 3.1e-08
      RuvB_N  35 hvllyGpPGlGkttlakiiakelgvk.lkitsgPvleka.gdlaalltnl....eekd..vlfideih 94 
                  vllyGpPG Gkt la+ +a+ l+++ lk+ s+ +++k  g+ a l+ ++    +e++  ++f+dei 
  EEA22771.1 173 GVLLYGPPGTGKTLLARAVASSLETNfLKVVSSAIVDKYiGESARLIREMfgyaKEHEpcIIFMDEID 240
                 69**********************99458899999988536666666665343333334488888886 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.0   1.3e-05    0.0061       8      30 ..     174     196 ..     169     209 .. 0.87
   2 ?    2.3   0.0      0.39   1.9e+02      70     117 ..     213     266 ..     196     284 .. 0.64

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 1.3e-05
      AAA_22   8 lvvtGesGtGKTtllrrlleqld 30 
                 ++++G++GtGKT+l+r ++++l+
  EEA22771.1 174 VLLYGPPGTGKTLLARAVASSLE 196
                 689***************99985 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.39
      AAA_22  70 aerlsseellealeqalraravielliiDEaqhlr....s.........eealeeLrslln 117
                 +   +s +l++ +  +++++    ++  DE++ +     s         +   ++L +lln
  EEA22771.1 213 G---ESARLIREMFGYAKEHEP-CIIFMDEIDAIGgrrfSegtsadreiQ---RTLMELLN 266
                 4...778888888888888888.9*********97755515556664441...33333333 PP

>> DUF815  Protein of unknown function (DUF815)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.0   1.4e-06   0.00066      41     116 ..     157     239 ..     125     257 .. 0.79

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 1.4e-06
      DUF815  41 venteqfleg..lpannvLLwGarGtGKSslvkallneyaeegLrlie..vekedlkelpklvellr...erperfilfvDDL 116
                 ++n e f++   +p + vLL+G  GtGK  l +a+ ++++++ L+++   +  + + e  +l++++    +++e +i+f+D +
  EEA22771.1 157 LKNPELFMRVgiKPPKGVLLYGPPGTGKTLLARAVASSLETNFLKVVSsaIVDKYIGESARLIREMFgyaKEHEPCIIFMDEI 239
                 45666676532368899******************************644777888888888888753437778899999975 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.1         3   1.4e+03      30      83 ..      15      69 ..       8      99 .. 0.67
   2 !   18.3   0.0   5.5e-06    0.0026       1      69 [.     174     270 ..     174     297 .. 0.74

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 3
      AAA_18 30 dvakenglllevdpealdeskrldedkldklldaleenssaleegknl...vidghl 83
                d+ k    l e++++   +s+r++++  +k  d+ een++al++ + +   v+ ++ 
  EEA22771.1 15 DYKKTLLDLREWEAK--LKSLRMEIKESQKEYDITEENIKALQSVGQIigeVLKQLD 69
                555555555566666..8888888888888888888888877766664333343333 PP

  == domain 2  score: 18.3 bits;  conditional E-value: 5.5e-06
      AAA_18   1 IlltGtpGvGKttlakeLskrl.gf....................gvnlrdvakenglllevdpe.......aldeskrldedkldklldaleenss 69 
                 +ll G+pG+GKt la++++++l  +                     ++   +ake+++++ + +e        ++e   +d++ +  l+++l++ + 
  EEA22771.1 174 VLLYGPPGTGKTLLARAVASSLeTNflkvvssaivdkyigesarlIREMFGYAKEHEPCIIFMDEidaiggrRFSEGTSADREIQRTLMELLNQLDG 270
                 799***************9998433688888877777777776666666667777777766666677777777777777777777777777777765 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.0   3.9e-06    0.0018      25     109 ..     163     239 ..     159     263 .. 0.80

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 3.9e-06
       AAA_7  25 llelllknkkpvllvGptGtGKtviikdllkkldkekylsltinfsaqtsanqlqdiiesklekrrkgvygPpggkklvvFvDDl 109
                 +++  +k  k vll+Gp GtGKt++++ + ++l+         nf +  s++ + + i ++    r+    ++ ++ +++F+D++
  EEA22771.1 163 FMRVGIKPPKGVLLYGPPGTGKTLLARAVASSLE--------TNFLKVVSSAIVDKYIGESARLIREMFGYAKEHEPCIIFMDEI 239
                 67777888899*******************9999........6777777777777777777777665555566677777777776 PP

>> TIP49  TIP49 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.1       7.2   3.4e+03     144     167 ..      32      55 ..      18      74 .. 0.60
   2 !   16.3   0.0     9e-06    0.0042      51      92 ..     172     211 ..     164     223 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 7.2
                 EEEEE-SS-EEEEEE-HHHHHHHH CS
       TIP49 144 kitlktakeekklklgskiaeell 167
                  + ++ ++ +k++++ ++ +++l+
  EEA22771.1  32 SLRMEIKESQKEYDITEENIKALQ 55 
                 444444455555555554444444 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 9e-06
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49  51 ravLlaGpsgtGktalaiaiskelgedvpfvalsgsevysle 92 
                 ++vLl Gp+gtGkt la a++ +l   + f ++++s +    
  EEA22771.1 172 KGVLLYGPPGTGKTLLARAVASSLE--TNFLKVVSSAIVDKY 211
                 89*********************97..789999998886655 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   1.9e-05    0.0089      20      59 ..     172     211 ..     145     222 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 1.9e-05
                 EEEEEEESTTSSHHHHHHHHHHHTT--..----TTTTSEEEE CS
        TsaE  20 dvilLeGdLGaGKTtlvrglakalgve..evkSPTFtlveeY 59 
                 + +lL+G+ G+GKT l+r++a++l+ +  +v S   ++v +Y
  EEA22771.1 172 KGVLLYGPPGTGKTLLARAVASSLETNflKVVSS--AIVDKY 211
                 349*********************9997876664..566666 PP

>> ATPase  KaiC
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.8   0.2      0.13        62      61     125 ..      10      75 ..       5      82 .. 0.82
   2 !   11.5   0.0   0.00029      0.14      13      37 ..     165     189 ..     137     195 .. 0.76
   3 ?   -2.4   0.0       5.2   2.4e+03     125     154 ..     239     268 ..     206     280 .. 0.62

  Alignments for each domain:
  == domain 1  score: 2.8 bits;  conditional E-value: 0.13
      ATPase  61 edlrenakslGwdlekleeegklaiidasesaeesaee.kdkedleelieelaeaikeikakrvvi 125
                 ++ +e+ k+   dl+++e++ k   +++ es++e+    ++ ++l+++ + + e++k++ ++r ++
  EEA22771.1  10 NQAIEDYKKTLLDLREWEAKLKSLRMEIKESQKEYDITeENIKALQSVGQIIGEVLKQLDEERFIV 75 
                 556777888889********9999999998888876655778888888999999999999999886 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 0.00029
      ATPase  13 kgGipegrvvlitGepGtGKtifal 37 
                   Gi   + vl++G pGtGKt++a 
  EEA22771.1 165 RVGIKPPKGVLLYGPPGTGKTLLAR 189
                 379999999*************985 PP

  == domain 3  score: -2.4 bits;  conditional E-value: 5.2
      ATPase 125 iDsitglayeekeavaReilrqlvrvlkkl 154
                 iD i+g   +e ++  Rei r+l++ l++l
  EEA22771.1 239 IDAIGGRRFSEGTSADREIQRTLMELLNQL 268
                 333333334445555666666666666654 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   2.1e-05      0.01       2      44 ..     174     229 ..     174     285 .. 0.76

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 2.1e-05
      AAA_33   2 vllvGlpGsGKstlaerllkklg...avllssdt..........lrrrlfgtdqqs 44 
                 vll G+pG+GK+ la+ ++  l      ++ss +          l+r +fg  +++
  EEA22771.1 174 VLLYGPPGTGKTLLARAVASSLEtnfLKVVSSAIvdkyigesarLIREMFGYAKEH 229
                 7899***************9999664444444446777777777666776655554 PP

>> Prot_ATP_OB_N  Proteasomal ATPase OB N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   2.5e-05     0.012      11      46 ..      70     105 ..      60     107 .. 0.86

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 2.5e-05
  Prot_ATP_OB_N  11 qdgtadVlvggrrmrVavsPlvdaeeLrpGqeVlLn 46 
                    +++ +   ++g r++V    +vd ++L+ G++V L+
     EEA22771.1  70 EERFIVKASSGPRYVVGCRSKVDKAKLKQGTRVALD 105
                    5666677899***********************996 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.5   0.0   1.8e-05    0.0086      24      45 ..     173     194 ..     162     214 .. 0.87

  Alignments for each domain:
  == domain 1  score: 15.5 bits;  conditional E-value: 1.8e-05
  Mg_chelatase  24 nlllvGppGsGKtmlakrlpsl 45 
                    +ll+GppG+GKt+la++++s 
    EEA22771.1 173 GVLLYGPPGTGKTLLARAVASS 194
                   589**************98765 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   2.5e-05     0.012       1      46 [.     174     210 ..     174     242 .. 0.68

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 2.5e-05
  RNA_helicase   1 iwlyGpsgeGKStlakeLakallkklklkkkdsvysrnpeddfwdg 46 
                   ++lyGp+g+GK++la+ +a++l++++          + +++ ++d+
    EEA22771.1 174 VLLYGPPGTGKTLLARAVASSLETNFL---------KVVSSAIVDK 210
                   689**************9988886652.........2233444444 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   2.5e-05     0.012      48      78 ..     172     202 ..     161     211 .. 0.83

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 2.5e-05
   IstB_IS21  48 enivllGpsGvGKshlaialgveavraglsv 78 
                 ++++l Gp+G+GK+ la a++ +  ++ l+v
  EEA22771.1 172 KGVLLYGPPGTGKTLLARAVASSLETNFLKV 202
                 6899****************98876665555 PP

>> AAA_14  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   3.5e-05     0.016       5      76 ..     174     242 ..     171     276 .. 0.73

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 3.5e-05
      AAA_14   5 lvitGaRrvGKTtllkqlikellvkkesilyinldderdkkladpekllelileklkeekktylflDEiqev 76 
                 +++ G+  +GKT l++ ++++l     ++l +      dk + ++++l+++++  +ke++  ++f+DEi  +
  EEA22771.1 174 VLLYGPPGTGKTLLARAVASSLE---TNFLKVVSSAIVDKYIGESARLIREMFGYAKEHEPCIIFMDEIDAI 242
                 7899**************98888...8888888888888777766555555555555578889******987 PP

>> AAA_24  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.1       1.2   5.8e+02      64     123 ..      14      73 ..       8     135 .. 0.70
   2 !   13.1   0.0   0.00012     0.058       5      26 ..     174     194 ..     171     258 .. 0.81

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 1.2
      AAA_24  64 adyktlviDtideleelclaev.irqnekaeskedkgdgkGygelaeefrrllkklqelrk 123
                 +dyk   +D  ++  +l++  + i+ ++k++++++  + k+ + +++ ++++lk+l+e r 
  EEA22771.1  14 EDYKKTLLDLREWEAKLKSLRMeIKESQKEYDITE-ENIKALQSVGQIIGEVLKQLDEERF 73 
                 67888888888888888888887788888778755.5558888888888888888877554 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 0.00012
      AAA_24   5 iliyGpsgiGKTtlakelgpkp 26 
                 +l+yGp+g+GKT la+    + 
  EEA22771.1 174 VLLYGPPGTGKTLLARAV-ASS 194
                 89************9987.444 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.0   0.0   6.6e-05     0.031      23      75 ..     172     227 ..     161     229 .. 0.67
   2 ?   -0.4   0.0       1.7   8.3e+02      87     105 ..     224     242 ..     219     285 .. 0.70

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 6.6e-05
                      S-EEEECSTTSSHHHHHHHHHHHSTTTTS-EEEEETTTS......-TTCHHHHHHEBSS CS
  Sigma54_activat  23 lsvlitGesGtGKellaraiheaskrkekpfvavncaai......peelleseLFGhek 75 
                        vl+ G  GtGK+llara+ ++ +    +f++v  +ai      ++  l  e+FG++k
       EEA22771.1 172 KGVLLYGPPGTGKTLLARAVASSLET---NFLKVVSSAIvdkyigESARLIREMFGYAK 227
                      679****************9876664...455555554411123333345567888875 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 1.7
                      HHHHHTTTSEEEEETGGGS CS
  Sigma54_activat  87 GlfekadgGtlfLDeigel 105
                      G+ ++ +  ++f+Dei  +
       EEA22771.1 224 GYAKEHEPCIIFMDEIDAI 242
                      6666667778888888754 PP

>> Thymidylate_kin  Thymidylate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.6   0.1     0.024        12     137     177 ..      39      80 ..      19      85 .. 0.83
   2 ?    7.1   0.0     0.008       3.8       3      30 ..     178     205 ..     176     241 .. 0.76

  Alignments for each domain:
  == domain 1  score: 5.6 bits;  conditional E-value: 0.024
                      TTSSTTTSHHHHHHHHHHHHHHHHHHHH.TTSTEEEEETTS- CS
  Thymidylate_kin 137 krdeldeeeeeqldflrkvrerylelak.ederiliidasks 177
                      + +++++  ee+++ l++v +   e++k  de+ +i++as+ 
       EEA22771.1  39 ESQKEYDITEENIKALQSVGQIIGEVLKqLDEERFIVKASSG 80 
                      334469***********************9******999975 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.008
                      ESTTSSHHHHHHHHHHHHHHTTE.EEEE CS
  Thymidylate_kin   3 GlDGaGKttqaellkerlkeegikvvlt 30 
                      G  G+GKt  a+++++ l+++ +kvv +
       EEA22771.1 178 GPPGTGKTLLARAVASSLETNFLKVVSS 205
                      6679*******************96654 PP

>> AAA_3  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   6.4e-05      0.03       2      30 ..     174     202 ..     173     211 .. 0.92

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 6.4e-05
       AAA_3   2 vllegvPGlaktllvkalakaldlefkri 30 
                 vll g PG++ktll++a+a++l+++f ++
  EEA22771.1 174 VLLYGPPGTGKTLLARAVASSLETNFLKV 202
                 7999*********************9887 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00023      0.11      21      53 ..     174     206 ..     166     223 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00023
      AAA_30  21 avltGpAGtGKttalkalreaweaaggrviglA 53 
                 ++l Gp+GtGKt + +a++  +e++  +v+  A
  EEA22771.1 174 VLLYGPPGTGKTLLARAVASSLETNFLKVVSSA 206
                 5789****************9999988887766 PP

>> GAS  Growth-arrest specific micro-tubule binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   1.9   7.7e-05     0.036      74     120 ..      10      56 ..       7      71 .. 0.93
   2 ?    0.1   0.1      0.93   4.4e+02     105     145 ..     346     387 ..     334     393 .] 0.73

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 7.7e-05
         GAS  74 rkqlknyekdkqslknlkarlkelekelkdlkwehevleqrfekvek 120
                 ++++++y+k   +l++ +a+lk+l +e+k+ + e+++ e+ ++++++
  EEA22771.1  10 NQAIEDYKKTLLDLREWEAKLKSLRMEIKESQKEYDITEENIKALQS 56 
                 57899**************************************9986 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.93
         GAS 105 kwehevleqrfekvekerdely.kkfeaaiqevqqktglknl 145
                  + + v e  f ++++erd ++ + f++a+++v +  +l+  
  EEA22771.1 346 DLRNVVTEAGFFAIKDERDSINqDDFNKAVRKVAEAKKLEGK 387
                 556677888899999999999625799999999887777655 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.3       1.9   8.9e+02     159     189 ..      22      52 ..       6      73 .. 0.72
   2 ?   11.0   0.0   0.00055      0.26      19      42 ..     173     196 ..     150     233 .. 0.81

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 1.9
      AAA_11 159 skskleqerrklkkerkelskeleeaeesle 189
                 + +++e++++ l+ e+ke +ke++ +ee+++
  EEA22771.1  22 DLREWEAKLKSLRMEIKESQKEYDITEENIK 52 
                 5567777788888888888888888887775 PP

  == domain 2  score: 11.0 bits;  conditional E-value: 0.00055
      AAA_11  19 itliqGPPGtgKTktivellsqll 42 
                  +l+ GPPGtgKT    ++ s+l 
  EEA22771.1 173 GVLLYGPPGTGKTLLARAVASSLE 196
                 5799*********98888888873 PP

>> PhoH  PhoH-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   0.00023      0.11      22      43 ..     174     195 ..     163     215 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00023
                 EEEE--TTSSTTHHHHHHHHHH CS
        PhoH  22 vfaiGpaGtGKtylavalavea 43 
                 v   Gp GtGKt+la a+a ++
  EEA22771.1 174 VLLYGPPGTGKTLLARAVASSL 195
                 7789***********9998654 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   0.00031      0.15       3      27 ..     174     198 ..     172     207 .. 0.89
   2 ?   -2.6   0.0       9.4   4.4e+03      87      94 ..     268     275 ..     233     289 .. 0.68

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00031
                 EEEEC-TTTCHHHHHHHHHHHHCTS CS
       NACHT   3 vilqGeaGsGKTtLlqklalawaeg 27 
                 v+l G++G GKT L++ +a+ + ++
  EEA22771.1 174 VLLYGPPGTGKTLLARAVASSLETN 198
                 799****************998765 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 9.4
                 EE-STT-S CS
       NACHT  87 lDglDelv 94 
                 lDg+D+l 
  EEA22771.1 268 LDGFDYLG 275
                 56666654 PP

>> DUF3363  Protein of unknown function (DUF3363)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.1   0.00027      0.13      26     125 ..      14     108 ..       6     132 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00027
     DUF3363  26 edleetLralGergdiirtmqralkakglerdlaifdeaaeeaepvvGrvvakgladelrdrlylivdgidGrahyvelgkgselealpkgaivevrpe 124
                 ed ++tL +l e +  ++++  ++k++  ++++ i  e++ +a + vG+++ + l+    d+  +iv +  G  + v ++++ ++++l++g+ v++ ++
  EEA22771.1  14 EDYKKTLLDLREWEAKLKSLRMEIKES--QKEYDIT-EENIKALQSVGQIIGEVLKQ--LDEERFIVKASSGPRYVVGCRSKVDKAKLKQGTRVALDMT 107
                 6889999999999999*********99..8899888.77888888899999999986..455668**************************99988776 PP

     DUF3363 125 e 125
                 +
  EEA22771.1 108 T 108
                 5 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   0.00036      0.17       2      25 ..     174     198 ..     173     241 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 0.00036
      AAA_28   2 ivitGgestGKTtlleaLaar.gyp 25 
                 + + G+++tGKT l++a a+  +++
  EEA22771.1 174 VLLYGPPGTGKTLLARAVASSlETN 198
                 6799**************9654333 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   0.00044      0.21      36      56 ..     174     194 ..     156     203 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00044
      AAA_25  36 allaGapgtGKttlaldlala 56 
                 +ll+G+pgtGKt la  +a +
  EEA22771.1 174 VLLYGPPGTGKTLLARAVASS 194
                 69************9888876 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.1   0.00055      0.26      11      38 ..     172     199 ..     166     384 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00055
      AAA_19  11 kvllvtaGpGtGKTrvlkhivallvelg 38 
                 k +l+ ++pGtGKT + +++ + l+ + 
  EEA22771.1 172 KGVLLYGPPGTGKTLLARAVASSLETNF 199
                 56899*********98877777666554 PP

>> Sec8_exocyst  Sec8 exocyst complex component specific domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.8   0.00062      0.29      68     128 ..      10      70 ..       8      76 .. 0.94

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00062
  Sec8_exocyst  68 nssiasYskilssiqesqekvselKesleeakkklstkkkeLkelnarsakykevieiLda 128
                   n++i  Y+k+l  + e + k++ l+ +++e++k+   +++++k l+   +   ev++ Ld+
    EEA22771.1  10 NQAIEDYKKTLLDLREWEAKLKSLRMEIKESQKEYDITEENIKALQSVGQIIGEVLKQLDE 70 
                   89********************************************999999999998886 PP

>> Zeta_toxin  Zeta toxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00052      0.25      15      47 ..     170     200 ..     161     206 .. 0.86

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00052
  Zeta_toxin  15 rPklillgGqpGAGKselaellkdelerqgnvv 47 
                  Pk +ll G pG GK+ la++++ +l  + n++
  EEA22771.1 170 PPKGVLLYGPPGTGKTLLARAVASSL--ETNFL 200
                 6999********************99..56655 PP

>> Parvo_NS1  Parvovirus non-structural protein NS1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00042       0.2     117     138 ..     174     195 ..     163     202 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00042
   Parvo_NS1 117 vwfyGpantGktnlaeaIakav 138
                 v++yGp+ tGkt la+a a  +
  EEA22771.1 174 VLLYGPPGTGKTLLARAVASSL 195
                 89***************99876 PP

>> DUF16  Protein of unknown function DUF16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   2.2    0.0013      0.59      25      87 ..      13      73 ..       9      79 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.0013
                HHHB-..BHHHHHHHHHHHH...HHHHHHHHHHHHHHHHHHHHHHHHHHHHH.......HHHH CS
       DUF16 25 lnefkdsnkqrLkkieakvdklgeqinkleqkvekqgekikelkveqkaqgeelnkvdetlel 87
                ++++k  +  +L++ eak+++l  +i++ +++ +  +e+ik l+   +  ge l+++de  ++
  EEA22771.1 13 IEDYK-KTLLDLREWEAKLKSLRMEIKESQKEYDITEENIKALQSVGQIIGEVLKQLDE-ERF 73
                56787.68889********************************9998888886655544.444 PP

>> DHHA1  DHHA1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.8    0.0024       1.1       5      92 ..      10      92 ..       8     104 .. 0.75
   2 ?    0.7   0.0       1.4   6.5e+02      39      79 ..     203     240 ..     183     267 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0024
                CHHHHHHHHHHHCHHHHHHHHHHHHHHHTCEEECTCEEEEEECHCCHHHHHHHHHHHHHHTHGBTTCEEEEEEEECTEEEEEEEESSH CS
       DHHA1  5 neerkelekeleelkealaklkaeellekaeevkgvkvlvaevgeewdagalgiaadklksklkkpvivfvakeegdkvkvsarskkd 92
                n+ +++ +k l +l+e +aklk   ++ k+    ++ + ++e  + +    +g+++++++++l++   ++ a+ +  ++ v +rsk d
  EEA22771.1 10 NQAIEDYKKTLLDLREWEAKLKSLRMEIKES---QKEYDITEE-NIKALQSVGQIIGEVLKQLDEERFIVKASSGP-RYVVGCRSKVD 92
                6777888899999999999999999987742...677777777.555669***********777755555555544.********976 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 1.4
                 TCEEEEEECHCCHHHHHHHHHHHHHHTHGBTTCEEEEEEEE CS
       DHHA1  39 gvkvlvaevgeewdagalgiaadklksklkkpvivfvakee 79 
                   + +v ++  +  a+ ++++ ++ k+  ++p i+f  + +
  EEA22771.1 203 VSSAIVDKY-IGESARLIREMFGYAKE--HEPCIIFMDEID 240
                 444455555.68888999999999999..999999988776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (393 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1100  (0.0613531); expected 358.6 (0.02)
Passed bias filter:                      820  (0.045736); expected 358.6 (0.02)
Passed Vit filter:                       140  (0.00780858); expected 17.9 (0.001)
Passed Fwd filter:                        38  (0.00211947); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              38  [number of targets reported over threshold]
# CPU time: 0.65u 0.35s 00:00:01.00 Elapsed: 00:00:00.48
# Mc/sec: 2449.29
//
Query:       EEA22772.1  [L=721]
Description: mannosyl-oligosaccharide alpha-1,2-mannosidase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.3e-168  561.6   0.1   1.6e-168  561.4   0.1    1.0  1  Glyco_hydro_47  Glycosyl hydrolase family 47
  ------ inclusion threshold ------
      0.031   14.0   0.0        3.3    7.5   0.0    2.5  2  DUF1028         Family of unknown function (DUF1028)


Domain annotation for each model (and alignments):
>> Glyco_hydro_47  Glycosyl hydrolase family 47
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  561.4   0.1  1.8e-172  1.6e-168       2     458 .]     162     704 ..     161     704 .. 0.95

  Alignments for each domain:
  == domain 1  score: 561.4 bits;  conditional E-value: 1.8e-172
                     HHHHHHHHHHHCTTSSEEETTTTEEE-SS..SS-CCHHHHHHHHHHCCHHHHHHHHHHHHHHC----S.SS.EEEHHHHHHHHHHHHHHHHHHH. CS
  Glyco_hydro_47   2 fkhswegYkkyAwghDelrPlskkgrdtf.gglgatlvDsLdtllimglkeefeeaveavekkidfdtsdskevsvFEttIRyLGGLlsaydls. 94 
                     f  sw++Y+ky+wg+De++P+s+kgr+++ gg+g+++vD+Ldt+++m+l++++++a++++++++++d +d+ +v++FEttIR+LGGLlsa++ls 
      EEA22772.1 162 FTISWDSYEKYGWGYDEYKPVSQKGRNMVqGGMGWIIVDALDTMILMNLTSRVQHARHWIHNSLRYD-QDH-DVNTFETTIRMLGGLLSAHYLSt 254
                     899**************************99************************************.577.99********************* PP

                     ...............S-HHHHHHHHHHHHHHHHGGGSSTTS---SEEETTT--EE-.STCGCEEEHHHHCSSHHHHHHHHHHHT-CHHHHHHHCC CS
  Glyco_hydro_47  95 ..............ekkedvllekAveladrLlpAFdtpsglpvarvnlkkrkaskkerassesvlAelgslslEftrLsqlTgdkkYedlaerv 175
                                   +++ed+++ekA++ladrLl+AF++psg+p+a++nl+++++  ++++ ++s++Ae+++++lEf++L++lTg+++Y++++e+v
      EEA22772.1 255 typnlapitdddpgAPGEDLYIEKATDLADRLLGAFESPSGVPYASINLNTSRGIPSHADGGASSTAEATTVQLEFKYLAKLTGESEYWEAVEHV 349
                     **************9******************************************************************************** PP

                     HHHHHCHCC.HHHTTB-BSEEETTT--EESTEE-SSTTTHHHHHHHHHHHHHCTS--HHHHHHHHHHHHHHHHH.TEEE-TTT..--EEE-EECT CS
  Glyco_hydro_47 176 tkaleelqektklpglvpikidastgkfvaekislgargDSyYEYllKqylllggeeeqyrkmyeealdaikkhllfrpskkkeddllfvgevts 270
                     +++++++q     +glvpi+i a++gkf++++i+lg+rgDSyYEYl+Kqyl++++ e++y++m++e+l +i kh l++++k++  ++++++e++ 
      EEA22772.1 350 MEVVDNNQ---AEDGLVPIFIYADSGKFRGNNIRLGSRGDSYYEYLIKQYLQTSEGEPIYKEMWDETLTGISKH-LITYTKNG--KMVVLAERPD 438
                     ******66...479************************************************************.67768777..79*****999 PP

                     TCTS.EE-EEEGGGGHHHHHHHHHHHTT-H..............HHHHHHHHHHHHHHHHHHHTSTTS---SEEEE-SS................ CS
  Glyco_hydro_47 271 teegklspeidhLscFlgGllalgakllek..............eedlelAkkltegcvkayeatktglmPEifevkpces.............. 337
                     + + +ls ++dhL+cF++G++alga++++               +e++ lA++l+++c+++y at+tgl+PEi+++k+++s              
      EEA22772.1 439 GLDRSLSAKMDHLVCFMPGTIALGATHGQLlakarqssswsrrqDEEILLARELMKTCWATYLATATGLAPEITYFKTDSSppmlsdvypnsall 533
                     9999**********************998889*********************************************988899999999999999 PP

                     ..........................S-ECTSSSSEEE-.GGG--B----HHHHHHHHHHHHH--THHHHHHHHHHHHHHHHCEETT........ CS
  Glyco_hydro_47 338 .......................aeecewneekkdealkriedrkyllRPEaiESlfylYritgdekyrevgwemfealekatktes........ 401
                                            ++++ w++   d +++  +d+++l+RPE++ESl y+Yritgde+yre+gw+mf+++ k+t++          
      EEA22772.1 534 rppesskdssytpkeldlisaplEDKNVWKS---DIQIH-SQDSHNLQRPETVESLLYMYRITGDEQYREWGWQMFKSFVKYTAVVEkvtpsdhk 624
                     8888877777777777777666544444544...55555.89*****************************************99555899**** PP

                     .......................EE--ECETTSSS-EE-S-B-HHHHHTHHHHHHHHC-S-TTT-TTTEEE-TTS-EEE- CS
  Glyco_hydro_47 402 .......................gysaledVtkeepekeDemeSFwlaEtlKYlYLlFsdedvlsldeyVfnTeAHplkr 458
                                            g+++l+d + ++p ++D+meSFw+aEtlKY+YLlFsd+d+++l+++VfnTeAH+++r
      EEA22772.1 625 gdestqlhvidndgeshpsyrivGFTSLSDANIDPPVMRDNMESFWMAETLKYFYLLFSDRDFIPLEDVVFNTEAHIFPR 704
                     ******************************************************************************86 PP

>> DUF1028  Family of unknown function (DUF1028)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.0    0.0051        46      15      75 ..     295     354 ..     289     361 .. 0.86
   2 ?    7.5   0.0   0.00036       3.3      47      91 ..     595     640 ..     590     649 .. 0.89

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.0051
                 EEEEEESSS-HHHHHEEEETTTEEEEEESS--HHHHHHHHHHHHTT--HHHHHHHHHHT-T CS
     DUF1028  15 GvAvaskslaVgalvpfaragvGavatQaltnpelgekglelleagasaeealeallaade 75 
                 Gv  as  l+ ++ +p    g Ga +t ++t ++l+ k l+ l  + +  ea+e++++  +
  EEA22772.1 295 GVPYASINLNTSRGIPSHADG-GASSTAEATTVQLEFKYLAKLTGESEYWEAVEHVMEVVD 354
                 777888888888889987777.********************************9997544 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.00036
                 HHHHHHHHHHHHTT--HHHHHHHHHHT-T.TGGG-EEEEEETTS-E CS
     DUF1028  47 pelgekglelleagasaeealeallaade.grelRQlavvdakget 91 
                  +++e+g ++ ++  + ++++e+++ +d+ g e  Ql+v+d +ge+
  EEA22772.1 595 EQYREWGWQMFKSFVKYTAVVEKVTPSDHkGDESTQLHVIDNDGES 640
                 68999********************77764789**********975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (721 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       466  (0.0259914); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.44
# Mc/sec: 4932.18
//
Query:       EEA22773.1  [L=171]
Description: hypothetical protein PMAA_093870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
  ------ inclusion threshold ------
       0.04   14.1  11.6       0.84    9.8   3.1    2.9  2  NACHT_sigma  Sigma domain on NACHT-NTPases


Domain annotation for each model (and alignments):
>> NACHT_sigma  Sigma domain on NACHT-NTPases
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   1.4   0.00017       3.1      12      29 ..      45      62 ..      44      65 .. 0.88
   2 ?    9.8   3.1   4.7e-05      0.84      12      41 ..     138     170 ..     137     171 .] 0.86

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00017
  NACHT_sigma 12 QfNapgGtQnnNtGsGnQ 29
                 Q Na+gG+Q n t +G Q
   EEA22773.1 45 QANASGGIQINHTENGTQ 62
                 899999999999999887 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 4.7e-05
  NACHT_sigma  12 QfNapgGtQnnN...tGsGnQFpGatFhGsvnF 41 
                  Q Na+ G+Q n    +G G +F G +F+  v+F
   EEA22773.1 138 QNNAGEGIQVNTifhSGTGYHFMGCQFNEKVYF 170
                  567777*****86668***************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (171 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1388  (0.0774165); expected 358.6 (0.02)
Passed bias filter:                      491  (0.0273858); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1244.14
//
Query:       EEA22774.1  [L=496]
Description: hypothetical protein PMAA_093880 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.8e-14   52.4   0.1    2.6e-05   24.7   0.1    4.1  4  Ank_2     Ankyrin repeats (3 copies)
    7.9e-13   48.7   5.7    1.4e-05   25.5   0.2    5.0  5  Ank_4     Ankyrin repeats (many copies)
    1.2e-10   40.6   8.5       0.58   10.9   0.0    7.1  8  Ank_3     Ankyrin repeat
      8e-10   38.8   1.6     0.0041   17.4   0.1    5.1  4  Ank_5     Ankyrin repeats (many copies)
    7.5e-06   26.2   4.8       0.59   10.7   0.0    6.0  6  Ank       Ankyrin repeat


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   4.1e-06     0.015      27      76 ..      62     121 ..      30     126 .. 0.77
   2 !   19.8   0.0   2.5e-07   0.00091       1      68 [.      65     154 ..      65     156 .. 0.73
   3 ?    2.0   0.0      0.09   3.2e+02      55      82 ..     210     237 ..     172     258 .. 0.77
   4 !   24.7   0.1   7.4e-09   2.6e-05      11      62 ..     348     410 ..     337     419 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 4.1e-06
       Ank_2  27 ktaLhyAakngnleivklLle.h......ad..ndgrtpLhyAarsghleivklLlek.g 76 
                 + +L++Aa++g+ e++++Lle +      ++  n   + L+ A+   + ++v++ l++ g
  EEA22774.1  62 EDILFHAASYGSPEALEILLEvYaaapeiVKgfNPKFNLLIDACAAANVDVVRFILDRhG 121
                 579*****************9525565553355567788*****9999*******96535 PP

  == domain 2  score: 19.8 bits;  conditional E-value: 2.5e-07
       Ank_2   1 LhlAakngnlelvklLl..egadpn..k...ngktaLhyAakngnleivklLle.h................adndgrtpLhyAarsghlei 68 
                 L++Aa++g++e++++Ll  + a p+  k    + + L+ A+ + n+++v+++l+ h                 dn+g tp+++Aa  g+le+
  EEA22774.1  65 LFHAASYGSPEALEILLevYAAAPEivKgfnPKFNLLIDACAAANVDVVRFILDrHgspenrlplgtvdlhqRDNSGDTPIIAAA--GSLEC 154
                 6789999999*******76333333332332337899999999999*******96366667788878665555599********8..77776 PP

  == domain 3  score: 2.0 bits;  conditional E-value: 0.09
       Ank_2  55 tpLhyAarsghleivklLlekgadinlk 82 
                 ++L +A++  + ++++ L+++gadi lk
  EEA22774.1 210 SVLGVAVSRANGRLIQRLIDSGADIYLK 237
                 5667777665667888888888887665 PP

  == domain 4  score: 24.7 bits;  conditional E-value: 7.4e-09
       Ank_2  11 elvklLl.egadpn..k.ngktaLhyAakng.nleivklLleh......adndgrtpLhyAar 62 
                 ++++l+l +ga++n  + ng+t+Lh++a+n  ++ ++k+L+ h      +d+  +t  h+Aar
  EEA22774.1 348 SILDLILsHGANINhaEnNGRTPLHVFARNLrQVSAAKFLITHgagfraQDSVRETSFHAAAR 410
                 478888899999997526***********96255789*****9988776667799******96 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1   0.0     0.042   1.5e+02       4      22 ..      64      82 ..      62      90 .. 0.83
   2 !   13.0   0.0   3.2e-05      0.12       4      43 ..     100     149 ..      99     154 .. 0.82
   3 !    5.9   0.0    0.0056        20       7      47 ..     214     252 ..     208     266 .. 0.80
   4 !   25.5   0.2   3.9e-09   1.4e-05      16      55 .]     349     388 ..     335     388 .. 0.93
   5 ?   -3.9   0.0         5   1.8e+04      37      44 ..     403     410 ..     402     411 .. 0.73

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.042
       Ank_4  4 aLhyaaisgrlelvrlLle 22
                +L++aa++g  e++++Lle
  EEA22774.1 64 ILFHAASYGSPEALEILLE 82
                7999999999999999995 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 3.2e-05
       Ank_4   4 aLhyaaisgrlelvrlLlek.gad..........inaqdnrsGetalhiAa 43 
                 +L  a+++ ++++vr++l++ g            ++ + ++sG+t+++ Aa
  EEA22774.1 100 LLIDACAAANVDVVRFILDRhGSPenrlplgtvdLHQR-DNSGDTPIIAAA 149
                 5788**************75464446666777779999.999******998 PP

  == domain 3  score: 5.9 bits;  conditional E-value: 0.0056
       Ank_4   7 yaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgn 47 
                  a++  + +l+++L+++gadi+     +++ +++  + + +
  EEA22774.1 214 VAVSRANGRLIQRLIDSGADIYLK--HQHFYPFQLSLTKDH 252
                 5667777789************98..999999998887777 PP

  == domain 4  score: 25.5 bits;  conditional E-value: 3.9e-09
       Ank_4  16 lvrlLlekgadinaqdnrsGetalhiAakrg.nveilklLl 55 
                 +++l+l++ga+in+   ++G+t+lh  a++  +v+++k+L+
  EEA22774.1 349 ILDLILSHGANINHA-ENNGRTPLHVFARNLrQVSAAKFLI 388
                 6899**********8.999************77*******8 PP

  == domain 5  score: -3.9 bits;  conditional E-value: 5
       Ank_4  37 talhiAak 44 
                 t +h Aa+
  EEA22774.1 403 TSFHAAAR 410
                 78888886 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.9   0.0   0.00016      0.58       5      29 ..      64      88 ..      60      90 .. 0.86
   2 !    6.3   0.1    0.0049        18       9      27 ..     104     122 ..     100     126 .. 0.88
   3 ?   -3.0   0.0         5   1.8e+04      14      27 ..     176     187 ..     172     189 .. 0.58
   4 !    6.3   0.0    0.0051        18       4      30 ..     210     235 ..     208     236 .. 0.91
   5 !    6.0   0.1    0.0063        23       8      31 .]     340     362 ..     337     362 .. 0.87
   6 !    8.9   0.0   0.00073       2.6       1      29 [.     366     394 ..     366     396 .. 0.73
   7 ?   -3.7   0.0         5   1.8e+04       3      11 ..     402     410 ..     402     410 .. 0.84
   8 ?   -0.0   0.0      0.59   2.1e+03       7      16 ..     415     424 ..     413     433 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.9 bits;  conditional E-value: 0.00016
       Ank_3  5 pLhlAarsgnleivkfLlenkgadv 29
                +L++Aa++g++e ++ Lle + a +
  EEA22774.1 64 ILFHAASYGSPEALEILLEVYAAAP 88
                79*****************877765 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0049
       Ank_3   9 AarsgnleivkfLlenkga 27 
                 A+ ++n+++v+f+l+ +g 
  EEA22774.1 104 ACAAANVDVVRFILDRHGS 122
                 9**************7775 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 5
       Ank_3  14 nleivkfLlenkga 27 
                 +  ++ +Ll+ +g+
  EEA22774.1 176 HR-LIYLLLD-WGC 187
                 44.3566666.776 PP

  == domain 4  score: 6.3 bits;  conditional E-value: 0.0051
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadvn 30 
                 + L +A++ +n  +++ L++  gad++
  EEA22774.1 210 SVLGVAVSRANGRLIQRLID-SGADIY 235
                 67889***************.9***97 PP

  == domain 5  score: 6.0 bits;  conditional E-value: 0.0063
       Ank_3   8 lAarsgnleivkfLlenkgadvna 31 
                 l ++s+ ++i++++l  +ga++n+
  EEA22774.1 340 LSLLSALYSILDLILS-HGANINH 362
                 667889999*******.9****96 PP

  == domain 6  score: 8.9 bits;  conditional E-value: 0.00073
       Ank_3   1 nGetpLh.lAarsgnleivkfLlenkgadv 29 
                 nG+tpLh +A     ++ +kfL+  +ga +
  EEA22774.1 366 NGRTPLHvFARNLRQVSAAKFLIT-HGAGF 394
                 7******55555555578999999.78865 PP

  == domain 7  score: -3.7 bits;  conditional E-value: 5
       Ank_3   3 etpLhlAar 11 
                 et +h Aar
  EEA22774.1 402 ETSFHAAAR 410
                 6999*9997 PP

  == domain 8  score: -0.0 bits;  conditional E-value: 0.59
       Ank_3   7 hlAarsgnle 16 
                  +++rsg++e
  EEA22774.1 415 DHVCRSGRYE 424
                 689*****97 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.8   0.0    0.0049        18      19      38 ..      64      84 ..      57      96 .. 0.79
   2 !    8.9   0.2   0.00055         2      17      37 ..      98     124 ..      94     148 .. 0.74
   3 ?   -1.6   0.0         1   3.6e+03      18      44 ..     210     236 ..     195     237 .. 0.79
   4 !   17.4   0.1   1.1e-06    0.0041       2      47 ..     354     399 ..     353     408 .. 0.91

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0049
       Ank_5 19 pLhvAakygaadvvrlLl.ar 38
                +L +Aa+yg+++ +++Ll  +
  EEA22774.1 64 ILFHAASYGSPEALEILLeVY 84
                6778**************544 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.00055
       Ank_5  17 ntpLhvAakygaadvvrlLl......a 37 
                 ++ L+ A+ + + dvvr++l      +
  EEA22774.1  98 FNLLIDACAAANVDVVRFILdrhgspE 124
                 589*****************7444441 PP

  == domain 3  score: -1.6 bits;  conditional E-value: 1
       Ank_5  18 tpLhvAakygaadvvrlLlargadlnl 44 
                 ++L vA+++ + +++++L++ gad+ l
  EEA22774.1 210 SVLGVAVSRANGRLIQRLIDSGADIYL 236
                 678899999999999999999999876 PP

  == domain 4  score: 17.4 bits;  conditional E-value: 1.1e-06
       Ank_5   2 lehgpadvnrldgggntpLhvAak.ygaadvvrlLlargadlnltds 47 
                 l+hg a++n+ +++g tpLhv a+  +  + +++L+ +ga  +++ds
  EEA22774.1 354 LSHG-ANINHAENNGRTPLHVFARnLRQVSAAKFLITHGAGFRAQDS 399
                 8999.*************************************99997 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.4   0.0      0.52   1.9e+03       7      22 ..      67      81 ..      65      92 .. 0.75
   2 ?    1.1   0.0      0.18   6.3e+02       9      27 ..     104     123 ..      98     139 .. 0.77
   3 ?   -0.0   0.0       0.4   1.4e+03       2      22 ..     141     183 ..     140     192 .. 0.53
   4 ?    2.3   0.0     0.073   2.6e+02       9      27 ..     215     234 ..     209     238 .. 0.76
   5 !    6.4   0.4    0.0036        13      11      29 ..     346     362 ..     326     365 .. 0.71
   6 !   10.7   0.0   0.00016      0.59       1      25 [.     366     392 ..     366     399 .. 0.79

  Alignments for each domain:
  == domain 1  score: -0.4 bits;  conditional E-value: 0.52
                HHHHHHTTHHHHHHHH CS
         Ank  7 HlAatngkkriiklLL 22
                H A+ +g+++ ++ LL
  EEA22774.1 67 HAAS-YGSPEALEILL 81
                6655.9**99999998 PP

  == domain 2  score: 1.1 bits;  conditional E-value: 0.18
                 HHHHTTHHHHHHHH..TTTST CS
         Ank   9 AatngkkriiklLL..hGAnl 27 
                 A+  +++++++++L  hG ++
  EEA22774.1 104 ACAAANVDVVRFILdrHG-SP 123
                 55567788***9998778.34 PP

  == domain 3  score: -0.0 bits;  conditional E-value: 0.4
                 SBBHHHHHH...........HHTT.............HHHHHHHH CS
         Ank   2 GnTPLHlAa...........tngk.............kriiklLL 22 
                 G+TP   Aa                            +r i lLL
  EEA22774.1 141 GDTPIIAAAgslecfvrntdE--EdktewvrnrisrgHRLIYLLL 183
                 889999887544444444331..0234444444555566666666 PP

  == domain 4  score: 2.3 bits;  conditional E-value: 0.073
                 HHHHTTHHHHHHHH.TTTST CS
         Ank   9 AatngkkriiklLL.hGAnl 27 
                 A+++++ r i+ L+ +GA++
  EEA22774.1 215 AVSRANGRLIQRLIdSGADI 234
                 665666689*****88***8 PP

  == domain 5  score: 6.4 bits;  conditional E-value: 0.0036
                 HHTTHHHHHHHH.TTTSTTC CS
         Ank  11 tngkkriiklLL.hGAnlna 29 
                  +    i+ l+L hGAn+n 
  EEA22774.1 346 LYS---ILDLILsHGANINH 362
                 334...88888999****96 PP

  == domain 6  score: 10.7 bits;  conditional E-value: 0.00016
                 TSBBHHHHHHHHTT..HHHHHHHH.TTT CS
         Ank   1 dGnTPLHlAatngk..kriiklLL.hGA 25 
                 +G+TPLH+ a ++   ++ +k+L+ hGA
  EEA22774.1 366 NGRTPLHVFA-RNLrqVSAAKFLItHGA 392
                 7******989.35555889999999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (496 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       636  (0.0354733); expected 358.6 (0.02)
Passed bias filter:                      542  (0.0302304); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.45
# Mc/sec: 3328.84
//
Query:       EEA22775.1  [L=516]
Description: cytochrome P450 family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.7e-55  186.3   0.3    1.1e-54  186.0   0.3    1.1  1  p450      Cytochrome P450


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  186.0   0.3   5.9e-59   1.1e-54      36     448 ..      79     498 ..      49     512 .. 0.78

  Alignments for each domain:
  == domain 1  score: 186.0 bits;  conditional E-value: 5.9e-59
                 EEEEEETTEEEEEEESHHHHHHHHCTSTTTTCEESSHHHHHHHHHTTTTSSSTTCGHHHHHHHHHHHHHHHTSH..STT.THHHHHHHHHHHHHHHHHC CS
        p450  36 ifrlklgskpvvvlsgpeavkevlikkgeefsgrpdeallatsrkpfkgkgvlfangekwkklRrfltptltsf..gkl.sleelveeeaedlveklrk 131
                 +f+l l + +++   +p  ++++l ++   fs+     l +++ +p +g+g+++a+g+ w+  R ++ p++  +    l   e+ v+e  ++lv    +
  EEA22775.1  79 TFGLSLFGSNFIQTAEPRNIQALLATQ---FSDFDLGDLRRQAFYPLLGNGIFTADGKAWEHSRAMIRPQFVRDqvADLaHEENHVQELLQQLV---TD 171
                 566666666777777777778888777...44444444555566789*************************9944444333344444444433...33 PP

                 CCCHCSEEETHHHHHHHHHHHHHHHHHSSHHHTTTSSH..HHHHHHHHHHHHHHHHCHHHHCCCCCHHHTCCSCHHHHHHHHHHHHHHHHHHHHHHHHH CS
        p450 132 kagesselditellskaaldvigsilFgarfdlledek..lselvkaveelssllskssvqllllfpllkylptkllrklkeavkklkdlldklieerr 228
                 k g  +  +i++l+++ ++d+ ++ lFg ++ + ++    +++++   ++l + ++   + l++ ++l+++ + +  ++++e v++++ ++d+++++  
  EEA22775.1 172 KLGWTKPTSIVPLIFRLTFDSTTEFLFGTNVYSQRQAGnqNETALFEWNTLAESFDLAKKHLCDRMQLAQFYWLHNPKEFRENVQEVHRFADFCVQNAL 270
                 333333678********************977544433333344434444555666666789999**99999999*******************99866 PP

                 HCHCHC.........SCSSCSHHHHHHHHCTTCTCTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHCCTTT...T-HH CS
        p450 229 etldsa.........kksrrdfldalllakkekkgesklsdeelaatvlellfaGvdTtsstlswaLyeLaknPevqeklreEidevlgdkr...epty 315
                 + +++          ++ +++fld l   +         +  el+ ++++ll+aG dTt+s lsw++ +L ++P + ++lr+ i e +g  +   ++t+
  EEA22775.1 271 KRVEQLdrqseksgnTRYNYTFLDELARVT--------KDPVELRSQAMNLLLAGRDTTASLLSWTIWLLGRHPAIFNRLRNQILEDFGPYEqteKITF 361
                 655555555976655555566666665554........3668**********************************************5444478**** PP

                 HHCCT-HHHHHHHHHHHHHSCSSTTEEEEESSSCEEET..T.......EEE-TT-EEEEEHHHHHT-TTTS.SSTTS--GGGGB-TTSCTESSCTT--T CS
        p450 316 ddlqklpyldavikEtLRlhpvvplllpRevtkdvvir..g.......ylipkGtevivnlyalhrdpevf.pnPeeFdpeRFldekgnskrksfaflP 404
                 + l++ +yl+ v++E+LRl+p+vp   +R++ kd++++  g        +++kG ev  ++y +hr++e++ ++++eF+p+R+ ++k        ++lP
  EEA22775.1 362 SSLKSCTYLQHVLNEVLRLYPPVP-MNSRRAVKDTTLPlgGgqdgkspLFVKKGVEVEYFVYVMHREEEFWgKDANEFNPDRWVSRKS-----GWEYLP 454
                 ************************.556888999998543246679999************************************965.....79**** PP

                 TEEGGGS-TTHHHHHHHHHHHHHHHHHHEEEEESTSTSGGEEES CS
        p450 405 FGaGpRnCiGerlArmelklflatlLqnFevelqpetdpppile 448
                 F  GpR+C+G+++A     ++++++Lq+F+    ++++  p+ +
  EEA22775.1 455 FNGGPRICLGQQFALTVAGYVISRILQRFDQLKLEDESFVPTHR 498
                 *****************************987667666665555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (516 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       562  (0.0313459); expected 358.6 (0.02)
Passed bias filter:                      495  (0.0276089); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 3277.57
//
Query:       EEA22776.1  [L=1634]
Description: ankyrin repeat domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   8.7e-246  795.3  38.0    1.1e-19   70.7   0.0   15.7 20  Ank_2     Ankyrin repeats (3 copies)
   2.7e-152  493.3  22.3      1e-12   48.3   0.0   22.1 24  Ank_4     Ankyrin repeats (many copies)
   1.5e-148  477.4  23.9    9.5e-07   29.0   0.0   32.4 34  Ank       Ankyrin repeat
   5.3e-145  453.5  16.2    6.4e-05   23.1   0.0   32.0 32  Ank_3     Ankyrin repeat
   1.9e-111  362.7  41.6    1.2e-10   41.4   0.0   24.7 28  Ank_5     Ankyrin repeats (many copies)
    2.2e-07   31.3   1.2    2.6e-05   24.6   0.2    2.6  2  HET       Heterokaryon incompatibility protein (HET)
    0.00094   19.0  22.5        2.7    8.0   0.0   11.3 13  VWA_3_C   von Willebrand factor type A C-terminal domain
  ------ inclusion threshold ------
      0.064   13.2   0.2        4.7    7.3   0.1    3.1  2  DUF5619   Domain of unknown function (DUF5619)


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.1   0.0         8   1.8e+04      52      60 ..     260     268 ..     254     275 .. 0.78
   2 !   35.7   0.0   4.3e-12   9.7e-09       1      83 []     553     644 ..     553     644 .. 0.79
   3 !   43.2   0.0     2e-14   4.4e-11      12      83 .]     597     677 ..     595     677 .. 0.83
   4 !   54.8   0.1   4.8e-18   1.1e-14       1      77 [.     618     703 ..     618     710 .. 0.85
   5 !   52.7   1.1   2.2e-17   4.8e-14       1      80 [.     651     740 ..     651     743 .. 0.89
   6 !   46.2   1.8   2.3e-15   5.1e-12       1      80 [.     684     773 ..     684     777 .. 0.84
   7 !   39.9   0.3   2.1e-13   4.8e-10       1      83 []     717     808 ..     717     808 .. 0.89
   8 !   57.4   0.0   7.4e-19   1.7e-15       1      83 []     781     874 ..     780     874 .. 0.85
   9 !   39.8   0.0   2.3e-13   5.1e-10      25      83 .]     876     939 ..     872     939 .. 0.87
  10 !   57.6   0.0   6.5e-19   1.5e-15       3      81 ..     947    1031 ..     945    1033 .. 0.90
  11 !   63.3   0.0   1.1e-20   2.4e-17       1      80 [.     974    1061 ..     974    1063 .. 0.90
  12 !   66.5   0.0     1e-21   2.3e-18       3      83 .]    1040    1123 ..    1038    1123 .. 0.92
  13 !   70.7   0.0   5.1e-23   1.1e-19       1      83 []    1064    1156 ..    1064    1156 .. 0.89
  14 !   52.4   0.0   2.7e-17     6e-14      24      83 .]    1124    1189 ..    1118    1189 .. 0.89
  15 !   47.0   0.0   1.3e-15     3e-12      26      83 .]    1159    1222 ..    1157    1222 .. 0.89
  16 !   53.8   0.0   9.9e-18   2.2e-14       4      80 ..    1232    1315 ..    1229    1318 .. 0.88
  17 !   60.5   0.0   7.9e-20   1.8e-16       1      83 []    1321    1414 ..    1321    1414 .. 0.90
  18 !   43.4   0.1   1.7e-14   3.8e-11      25      81 ..    1417    1479 ..    1412    1481 .. 0.85
  19 !   49.1   0.0   2.9e-16   6.4e-13      25      83 .]    1483    1546 ..    1477    1546 .. 0.88
  20 !   36.1   0.0   3.4e-12   7.5e-09      25      79 ..    1548    1608 ..    1545    1611 .. 0.87

  Alignments for each domain:
  == domain 1  score: -4.1 bits;  conditional E-value: 8
       Ank_2  52 dgrtpLhyA 60 
                  g+t+L +A
  EEA22776.1 260 RGWTALELA 268
                 589999888 PP

  == domain 2  score: 35.7 bits;  conditional E-value: 4.3e-12
       Ank_2   1 LhlAakngnl.elvklL.legadpn..k.ngktaLhyAakngnleivklLleh.....adndgrtpLhyAarsghleivklLlekgadinlkd 83 
                 L+lA++ g++ e+++l  + ga+ +  +   +taLhyA    +  +v++L+       +d  g+++Lh+A++ g+++iv lLl +gad+n++d
  EEA22776.1 553 LILASRVGDDkEVCRLVeI-GANSSweDeRTWTALHYASWLCYDRVVETLIGSsghsaLDHLGQSALHLASERGSQKIVGLLLARGADPNIQD 644
                 6778887756256665544.55544543588*******99766699*****73345889999*********************99*****997 PP

  == domain 3  score: 43.2 bits;  conditional E-value: 2e-14
       Ank_2  12 lvklLl..egadpn.kngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinlkd 83 
                 +v+ L+  +g+ +  + g++aLh+A ++g+ +iv lLl+       +d++g+t+Lh Aa+ + ++iv+ Ll  gad+n++d
  EEA22776.1 597 VVETLIgsSGHSALdHLGQSALHLASERGSQKIVGLLLARgadpniQDSKGQTALHRAAWGSCTQIVEQLLLGGADPNIQD 677
                 78899965443333249*********************966566667799*********66789****99978*****997 PP

  == domain 4  score: 54.8 bits;  conditional E-value: 4.8e-18
       Ank_2   1 LhlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekga 77 
                 LhlA++ g+ ++v lLl  gadpn  + +g+taLh Aa + +++iv+ Ll        +d+ g+t+Lh+Aa+++h+e+v+lL  +ga
  EEA22776.1 618 LHLASERGSQKIVGLLLaRGADPNiqDsKGQTALHRAAWGSCTQIVEQLLLGgadpniQDSVGKTALHVAAQYSHIETVQLLA-NGA 703
                 8*****99889*************9537******************6666433455566788********************9.655 PP

  == domain 5  score: 52.7 bits;  conditional E-value: 2.2e-17
       Ank_2   1 LhlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadin 80 
                 Lh Aa    +++v++Ll  gadpn  +  gktaLh+Aa++ ++e+v+lL +        d++g+ pLh+Aa+ g + i+ lLl+ gad+ 
  EEA22776.1 651 LHRAAWGSCTQIVEQLLlGGADPNiqDsVGKTALHVAAQYSHIETVQLLANGasnlyiSDCHGNHPLHVAAEAGDIIILHLLLDAGADLS 740
                 899***88789*****99******9537**********************9444577777**************999999***99**986 PP

  == domain 6  score: 46.2 bits;  conditional E-value: 2.3e-15
       Ank_2   1 LhlAakngnlelvklLlegadpn...k..ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadin 80 
                 Lh+Aa++ + e+v+lL +ga  n   +   g+ +Lh+Aa++g++ i+ lLl++      +++dg+ +Lh+Aa  gh  iv++L ek+a++ 
  EEA22776.1 684 LHVAAQYSHIETVQLLANGAS-NlyiSdcHGNHPLHVAAEAGDIIILHLLLDAgadlsvLNSDGWRALHLAAARGHDAIVRMLREKDASLV 773
                 8*****9999*******8855.344424689***********77778****97766677779**********99**********9988765 PP

  == domain 7  score: 39.9 bits;  conditional E-value: 2.1e-13
       Ank_2   1 LhlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh....adndgrtpLhyAarsghleivklLl.ekgadinlkd 83 
                 Lh+Aa+ g+  +++lLl +gad++  + +g+ aLh+Aa +g+  iv++L e+    + +d +  L+ Aa+ g + ++  Ll +++adi ++d
  EEA22776.1 717 LHVAAEAGDIIILHLLLdAGADLSvlNsDGWRALHLAAARGHDAIVRMLREKdaslVCSDTWKLLQSAAKGGLEWVIHELLrDNEADICITD 808
                 8******9887888888*****988746**************999*****9886654499*********99999*******7889***9987 PP

  == domain 8  score: 57.4 bits;  conditional E-value: 7.4e-19
       Ank_2   1 LhlAakngnlelvklLl..egadpn..k.ngktaLhyAakngnleiv.klLleh......adndgrtpLhyAarsghleivklLlekgadinlkd 83 
                 L+ Aak g   +++ Ll  ++ad+   + +g+ aLh Aa++g+ eiv + Lle+       d++ rtpL +Aa++gh+ +v+lLlekgad+n kd
  EEA22776.1 781 LQSAAKGGLEWVIHELLrdNEADICitDsEGRLALHRAAEGGS-EIVaRQLLEKgvdidsKDRNRRTPLSWAAQNGHEAVVRLLLEKGADPNSKD 874
                 56688888557******887788777537*************8.7755*****8866554448899**************************998 PP

  == domain 9  score: 39.8 bits;  conditional E-value: 2.3e-13
       Ank_2  25 ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinlkd 83 
                 ++kt+L++Aa ng++ +++lL+e+       d++grt + +Aa+ g++++v+ Lle+g di+lkd
  EEA22776.1 876 KDKTPLWWAAGNGHEAAIRLLIENganyksKDEYGRTLIWWAAEDGYENVVRQLLEYG-DIDLKD 939
                 569***********999*****977555555599*********99**********998.999887 PP

  == domain 10  score: 57.6 bits;  conditional E-value: 6.5e-19
       Ank_2    3 lAakngnlelvklLl.egadpnkngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinl 81  
                   Aa+ng+  +v+lL+ ++adpn   +t L +Aa+ng+  +v+ Lle+       d++g+t L +Aa++gh+ +v+lLl++ ad+n 
  EEA22776.1  947 RAAENGHETVVQLLVaNSADPN-SSQTMLSWAAENGHDAVVRKLLENgtdpmlKDSSGQTSLWLAAKNGHEAVVRLLLKHRADPNS 1031
                  79****999*****9999***9.679***********9999*****88666655599*********************99****97 PP

  == domain 11  score: 63.3 bits;  conditional E-value: 1.1e-20
       Ank_2    1 LhlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh.ad..ndgr.tpLhyAarsghleivklLlekgadin 80  
                  L +Aa+ng++ +v+ Ll +g+dp   +  g+t L++Aakng++ +v+lLl+h ad  ++g  +pL  Aa++g+  +v+lLle+gad+n
  EEA22776.1  974 LSWAAENGHDAVVRKLLeNGTDPMlkDsSGQTSLWLAAKNGHEAVVRLLLKHrADpnSNGVdSPLRRAAENGYKAVVRLLLESGADPN 1061
                  689*****999***********988537**************999*******9555566666************************99 PP

  == domain 12  score: 66.5 bits;  conditional E-value: 1e-21
       Ank_2    3 lAakngnlelvklLl.egadpnkngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinlkd 83  
                   Aa+ng+  +v+lLl +gadpn    + L +Aakng++ +v+lL+e+       d+ g+tpLh+Aa+sgh+++++lLlekga i+ kd
  EEA22776.1 1040 RAAENGYKAVVRLLLeSGADPN----SGLNFAAKNGHIAVVRLLVENgaghslKDDRGWTPLHMAAESGHEDVIRLLLEKGACIESKD 1123
                  79***9889************9....99*****************966666877799*************************999887 PP

  == domain 13  score: 70.7 bits;  conditional E-value: 5.1e-23
       Ank_2    1 LhlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinlkd 83  
                  L +Aakng+  +v+lL+ +ga  +  +  g+t+Lh Aa++g++++++lLle+       d +grtpL +A+r+gh+ +++lLl++ga++ +kd
  EEA22776.1 1064 LNFAAKNGHIAVVRLLVeNGAGHSlkDdRGWTPLHMAAESGHEDVIRLLLEKgaciesKDHEGRTPLWWASRNGHEAVIQLLLKNGAELCIKD 1156
                  668*****99*******97766556436***********************88787766699*********************99****9997 PP

  == domain 14  score: 52.4 bits;  conditional E-value: 2.7e-17
       Ank_2   24 kngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinlkd 83  
                  ++g+t+L++A +ng++ +++lLl++       d++ +tpL++Aa++gh+++++lLle+ ad++ kd
  EEA22776.1 1124 HEGRTPLWWASRNGHEAVIQLLLKNgaelciKDDHDWTPLQMAAENGHEDVAQLLLENAADVESKD 1189
                  389************9999****988677766699***************************9987 PP

  == domain 15  score: 47.0 bits;  conditional E-value: 1.3e-15
       Ank_2   26 gktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinlkd 83  
                  ++t+L+ Aa+ng++++++lLle+       d++g+tpL  Aa++gh+ iv+lL+++ga++  kd
  EEA22776.1 1159 DWTPLQMAAENGHEDVAQLLLENaadvesKDREGQTPLRKAAENGHEGIVRLLIKNGANPMSKD 1222
                  59*******************988665544599*********************99***99887 PP

  == domain 16  score: 53.8 bits;  conditional E-value: 9.9e-18
       Ank_2    4 AakngnlelvklLl.egadpn...k.ngktaLhyAakngnleivklLleh.adndgrt.pLhyAarsghleivklLlekgadin 80  
                  A+kng+  +v+lLl +g dp+   + n +t L +A +ng++ iv+lLle+ ad++g + pL yAa++gh+ +v+lLl++ +d+n
  EEA22776.1 1232 AVKNGHKAVVQLLLeNGPDPGpraDnNIRTLLVWASENGHEAIVRLLLEKgADSKGSNwPLWYAAENGHEGVVRLLLKNSVDPN 1315
                  8999*999*******9999988653577*********************9999666643******************8889988 PP

  == domain 17  score: 60.5 bits;  conditional E-value: 7.9e-20
       Ank_2    1 LhlAakngnlelvklLl.egadpn..k..ngktaLhyAakngnleivklLleh.ad.....ndgrtpLhyAarsghleivklLlekgadinlkd 83  
                  L  A+ ng+le+ +lLl +gad++  +  n++ +L++Aa++gn+ +v++Lle+ ad     ++g t+L  Aa +gh+ +v+lLle+g di+l+d
  EEA22776.1 1321 LLGAVDNGHLEVTRLLLkNGADVEseDyfNKRRPLWIAAEKGNEAVVRILLENgADprskhSNGDTALSSAANKGHEPVVRLLLENGTDIELTD 1414
                  567999*****************97538999************999******88444456799*********99****************9987 PP

  == domain 18  score: 43.4 bits;  conditional E-value: 1.7e-14
       Ank_2   25 ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinl 81  
                   +kt+L++A+ + +  + +lLle+       + +g tpLh Aar+g++ +v+lL+e+ga+i+ 
  EEA22776.1 1417 GNKTPLWWATTREHAAVTRLLLENganaklKNAHGDTPLHDAARYGNEAVVRLLIENGAEIES 1479
                  459**********98889****978555554488**************************986 PP

  == domain 19  score: 49.1 bits;  conditional E-value: 2.9e-16
       Ank_2   25 ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinlkd 83  
                   g+t+Lh+A+ n  ++ivk Lle+       d++g+tpL+ Aar+g++ +++lLlekgad+n kd
  EEA22776.1 1483 RGETPLHCATGNR-RDIVKVLLENganiksKDEQGQTPLQRAAREGNEAAIRLLLEKGADPNSKD 1546
                  69*******9986.6*******988566555599****************************998 PP

  == domain 20  score: 36.1 bits;  conditional E-value: 3.4e-12
       Ank_2   25 ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadi 79  
                  ++kt+L++A+ ng++ +++lL+e+       d++grt + +Aa++gh  +v+lL ++g+++
  EEA22776.1 1548 KDKTPLWWATGNGHVAVMRLLIENgadpklKDEQGRTLMWWAAENGHKTAVQLLKDYGISM 1608
                  469********************88566655599******************999999876 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.0     0.073   1.6e+02      32      43 ..     579     590 ..     568     602 .. 0.82
   2 !   14.4   0.1     2e-05     0.044       2      55 .]     583     634 ..     582     634 .. 0.87
   3 !   32.4   0.0   4.5e-11     1e-07       3      52 ..     616     664 ..     614     667 .. 0.91
   4 !   16.8   0.0   3.5e-06    0.0077      19      54 ..     666     699 ..     657     700 .. 0.83
   5 !   35.4   0.7   4.9e-12   1.1e-08       2      54 ..     714     765 ..     713     766 .. 0.93
   6 !   12.2   0.0   9.6e-05      0.21      19      48 ..     796     824 ..     778     831 .. 0.84
   7 !   23.6   0.0   2.5e-08   5.7e-05       2      52 ..     812     861 ..     811     861 .. 0.95
   8 !   42.1   0.0   3.9e-14   8.7e-11       1      55 []     844     897 ..     844     897 .. 0.98
   9 !   22.8   0.0   4.6e-08    0.0001       3      52 ..     879     927 ..     879     930 .. 0.90
  10 !   16.9   0.0   3.3e-06    0.0074       1      55 []     910     961 ..     910     961 .. 0.91
  11 !   10.1   0.0   0.00044      0.98       3      30 ..     943     970 ..     940     974 .. 0.88
  12 !   30.0   0.0   2.5e-10   5.5e-07       5      55 .]     974    1023 ..     971    1023 .. 0.94
  13 !   23.0   0.0   3.9e-08   8.8e-05       3      55 .]    1036    1080 ..    1034    1080 .. 0.94
  14 !   48.3   0.0   4.7e-16     1e-12       2      55 .]    1094    1146 ..    1093    1146 .. 0.97
  15 !   39.9   0.0   1.9e-13   4.2e-10       2      55 .]    1160    1212 ..    1159    1212 .. 0.97
  16 !   26.3   0.0   3.6e-09   8.1e-06       7      55 .]    1231    1279 ..    1226    1279 .. 0.95
  17 !   19.8   0.0   3.8e-07   0.00085       4      55 .]    1291    1337 ..    1289    1337 .. 0.94
  18 ?    5.4   0.0     0.013        29       8      27 ..    1324    1343 ..    1319    1350 .. 0.87
  19 !   20.5   0.0   2.4e-07   0.00054       2      42 ..    1352    1391 ..    1351    1392 .. 0.91
  20 !   31.4   0.0     9e-11     2e-07       2      55 .]    1385    1438 ..    1384    1438 .. 0.92
  21 !   27.8   0.0   1.2e-09   2.6e-06       2      44 ..    1452    1493 ..    1451    1496 .. 0.91
  22 !   26.1   0.0   4.2e-09   9.5e-06      15      55 .]    1497    1536 ..    1493    1536 .. 0.95
  23 !   31.7   0.0     7e-11   1.6e-07       5      55 .]    1520    1569 ..    1520    1569 .. 0.96
  24 !   25.2   0.0     8e-09   1.8e-05      12      54 ..    1560    1601 ..    1559    1601 .. 0.96

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.073
       Ank_4  32 nrsGetalhiAa 43 
                 +++ +talh+A 
  EEA22776.1 579 DERTWTALHYAS 590
                 67799*****97 PP

  == domain 2  score: 14.4 bits;  conditional E-value: 2e-05
       Ank_4   2 ltaLhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +taLhya   +  ++v+ L+ + g +  a  +  G++alh A  rg+ +i+ lLl
  EEA22776.1 583 WTALHYASWLCYDRVVETLIGSsGHS--AL-DHLGQSALHLASERGSQKIVGLLL 634
                 79******************654887..55.777************999888886 PP

  == domain 3  score: 32.4 bits;  conditional E-value: 4.5e-11
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilk 52 
                 +aLh a + g  ++v lLl++gad+n q ++ G+talh+Aa+++  +i++
  EEA22776.1 616 SALHLASERGSQKIVGLLLARGADPNIQ-DSKGQTALHRAAWGSCTQIVE 664
                 69**************************.999*********988666665 PP

  == domain 4  score: 16.8 bits;  conditional E-value: 3.5e-06
       Ank_4  19 lLlekgadinaqdnrsGetalhiAakrgnveilklL 54 
                 lLl  gad+n q ++ G talh Aa+ +++e ++lL
  EEA22776.1 666 LLL-GGADPNIQ-DSVGKTALHVAAQYSHIETVQLL 699
                 444.49******.888******************99 PP

  == domain 5  score: 35.4 bits;  conditional E-value: 4.9e-12
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54 
                 +++Lh aa++g++ +++lLl+ gad+    n++G+ alh Aa rg+  i+++L
  EEA22776.1 714 NHPLHVAAEAGDIIILHLLLDAGADLSVL-NSDGWRALHLAAARGHDAIVRML 765
                 689*************************9.****************7777776 PP

  == domain 6  score: 12.2 bits;  conditional E-value: 9.6e-05
       Ank_4  19 lLlekgadinaqdnrsGetalhiAakrgnv 48 
                 lL ++ adi+ + +++G+ alh+Aa +g+ 
  EEA22776.1 796 LLRDNEADICIT-DSEGRLALHRAAEGGSE 824
                 566899*****9.*************9986 PP

  == domain 7  score: 23.6 bits;  conditional E-value: 2.5e-08
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilk 52 
                 + aLh+aa+ g + ++r Llekg+di+   +r+ +t+l  Aa++g+  +++
  EEA22776.1 812 RLALHRAAEGGSEIVARQLLEKGVDIDSK-DRNRRTPLSWAAQNGHEAVVR 861
                 679*************************9.****************99885 PP

  == domain 8  score: 42.1 bits;  conditional E-value: 3.9e-14
       Ank_4   1 eltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++t+L +aa+ g++ +vrlLlekgad+n   +  + t+l+ Aa +g+  +++lL+
  EEA22776.1 844 RRTPLSWAAQNGHEAVVRLLLEKGADPNSK-DHKDKTPLWWAAGNGHEAAIRLLI 897
                 689**************************9.**********************98 PP

  == domain 9  score: 22.8 bits;  conditional E-value: 4.6e-08
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilk 52 
                 t+L +aa  g++ ++rlL+e+ga+    ++++G+t+++ Aa  g+ ++++
  EEA22776.1 879 TPLWWAAGNGHEAAIRLLIENGANYKS-KDEYGRTLIWWAAEDGYENVVR 927
                 79**********************666.5************999988887 PP

  == domain 10  score: 16.9 bits;  conditional E-value: 3.3e-06
       Ank_4   1 eltaLhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAakrgnveilklLl 55 
                 ++t++ +aa++g + +vr Lle+ ++d    + ++  ++l +Aa +g+  +++lL+
  EEA22776.1 910 GRTLIWWAAEDGYENVVRQLLEYgDID----LKDEYGPLLRRAAENGHETVVQLLV 961
                 589********************5599....457799*****************96 PP

  == domain 11  score: 10.1 bits;  conditional E-value: 0.00044
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaq 30 
                 ++L +aa+ g++ +v+lL+++ ad+n +
  EEA22776.1 943 PLLRRAAENGHETVVQLLVANSADPNSS 970
                 57899999****************9975 PP

  == domain 12  score: 30.0 bits;  conditional E-value: 2.5e-10
       Ank_4    5 LhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  L +aa+ g+  +vr Lle+g d+ + +++sG+t l+ Aak+g+  +++lLl
  EEA22776.1  974 LSWAAENGHDAVVRKLLENGTDP-MLKDSSGQTSLWLAAKNGHEAVVRLLL 1023
                  789*******************8.556***********************8 PP

  == domain 13  score: 23.0 bits;  conditional E-value: 3.9e-08
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  ++L +aa+ g   +vrlLle+gad+n          l +Aak+g++ +++lL+
  EEA22776.1 1036 SPLRRAAENGYKAVVRLLLESGADPNSG--------LNFAAKNGHIAVVRLLV 1080
                  799*********************9986........***************96 PP

  == domain 14  score: 48.3 bits;  conditional E-value: 4.7e-16
       Ank_4    2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  +t+Lh+aa+sg+++++rlLlekga i    + +G+t+l+ A ++g+  +++lLl
  EEA22776.1 1094 WTPLHMAAESGHEDVIRLLLEKGACIESK-DHEGRTPLWWASRNGHEAVIQLLL 1146
                  79************************998.***********************8 PP

  == domain 15  score: 39.9 bits;  conditional E-value: 1.9e-13
       Ank_4    2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  +t+L +aa+ g++++++lLle+ ad+    +r+G+t+l +Aa +g+  i++lL+
  EEA22776.1 1160 WTPLQMAAENGHEDVAQLLLENAADVESK-DREGQTPLRKAAENGHEGIVRLLI 1212
                  589*************************8.***********************8 PP

  == domain 16  score: 26.3 bits;  conditional E-value: 3.6e-09
       Ank_4    7 yaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  +a++ g+  +v+lLle+g+d+  +++++ +t+l  A  +g+  i++lLl
  EEA22776.1 1231 SAVKNGHKAVVQLLLENGPDPGPRADNNIRTLLVWASENGHEAIVRLLL 1279
                  68899*******************************************8 PP

  == domain 17  score: 19.8 bits;  conditional E-value: 3.8e-07
       Ank_4    4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  +L yaa+ g++ +vrlLl + +d+n       + +l  A+ +g++e+++lLl
  EEA22776.1 1291 PLWYAAENGHEGVVRLLLKNSVDPNDL-----QRPLLGAVDNGHLEVTRLLL 1337
                  699*******************98888.....77****************98 PP

  == domain 18  score: 5.4 bits;  conditional E-value: 0.013
       Ank_4    8 aaisgrlelvrlLlekgadi 27  
                  a+  g+le+ rlLl +gad+
  EEA22776.1 1324 AVDNGHLEVTRLLLKNGADV 1343
                  6678**************97 PP

  == domain 19  score: 20.5 bits;  conditional E-value: 2.4e-07
       Ank_4    2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiA 42  
                  +++L  aa++g++ +vr+Lle+gad+     ++G+tal  A
  EEA22776.1 1352 RRPLWIAAEKGNEAVVRILLENGADPRSK-HSNGDTALSSA 1391
                  679**********************9998.999****9655 PP

  == domain 20  score: 31.4 bits;  conditional E-value: 9e-11
       Ank_4    2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGe.talhiAakrgnveilklLl 55  
                   taL +aa++g++++vrlLle+g di  + + +G+ t+l+ A  r++  +++lLl
  EEA22776.1 1385 DTALSSAANKGHEPVVRLLLENGTDIELT-DQNGNkTPLWWATTREHAAVTRLLL 1438
                  699*************************9.656666****************997 PP

  == domain 21  score: 27.8 bits;  conditional E-value: 1.2e-09
       Ank_4    2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAak 44  
                   t+Lh aa +g++ +vrlL+e+ga+i    n +Get+lh+A  
  EEA22776.1 1452 DTPLHDAARYGNEAVVRLLIENGAEIES-ENWRGETPLHCATG 1493
                  69***********************988.5988********75 PP

  == domain 22  score: 26.1 bits;  conditional E-value: 4.2e-09
       Ank_4   15 elvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  ++v+ Lle+ga+i    +++G+t+l++Aa+ gn  +++lLl
  EEA22776.1 1497 DIVKVLLENGANIKSK-DEQGQTPLQRAAREGNEAAIRLLL 1536
                  789**********998.**********************98 PP

  == domain 23  score: 31.7 bits;  conditional E-value: 7e-11
       Ank_4    5 LhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  L +aa +g++ ++rlLlekgad+n   +  + t+l+ A  +g+v + +lL+
  EEA22776.1 1520 LQRAAREGNEAAIRLLLEKGADPNSK-DHKDKTPLWWATGNGHVAVMRLLI 1569
                  568999*******************9.**********************98 PP

  == domain 24  score: 25.2 bits;  conditional E-value: 8e-09
       Ank_4   12 grlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54  
                  g++ + rlL+e+gad+    +++G+t+++ Aa +g++ +++lL
  EEA22776.1 1560 GHVAVMRLLIENGADPKLK-DEQGRTLMWWAAENGHKTAVQLL 1601
                  8999***********9887.*********************98 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       7.1   1.6e+04       2      10 ..     261     269 ..     260     286 .. 0.61
   2 ?   -3.4   0.0       7.6   1.7e+04       7      26 ..     554     574 ..     553     574 .. 0.70
   3 !    9.3   0.0   0.00073       1.6       3      24 ..     583     606 ..     583     612 .. 0.75
   4 !   27.4   0.0   1.4e-09   3.1e-06       2      31 ..     614     644 ..     613     645 .. 0.95
   5 !   26.4   0.0   2.7e-09   6.1e-06       2      31 ..     647     677 ..     646     678 .. 0.84
   6 !   14.6   0.1   1.5e-05     0.034       2      29 ..     680     708 ..     680     711 .. 0.81
   7 !   15.5   1.8     8e-06     0.018       1      31 [.     712     743 ..     712     744 .. 0.88
   8 !    8.6   0.0    0.0012       2.6       1      22 [.     745     766 ..     745     777 .. 0.81
   9 ?    0.3   0.0      0.51   1.1e+03      17      31 ..     792     808 ..     780     809 .. 0.78
  10 !   10.1   0.0    0.0004      0.91       2      31 ..     811     841 ..     810     842 .. 0.83
  11 !   25.0   0.0   8.1e-09   1.8e-05       3      31 ..     845     874 ..     843     875 .. 0.95
  12 !   11.9   0.0   0.00011      0.24       3      26 ..     878     902 ..     877     907 .. 0.92
  13 !    6.4   0.0    0.0061        14       1      31 [.     909     939 ..     909     940 .. 0.89
  14 !    8.3   0.0    0.0015       3.4       8      29 ..     947     969 ..     941     972 .. 0.87
  15 ?    5.2   0.0     0.015        33       4      31 ..     972    1000 ..     970    1001 .. 0.90
  16 !   19.5   0.0   4.2e-07   0.00095       2      29 ..    1003    1031 ..    1002    1033 .. 0.95
  17 !   13.9   0.0   2.5e-05     0.055       4      29 ..    1036    1062 ..    1035    1063 .. 0.92
  18 ?    2.6   0.1     0.092   2.1e+02       9      25 ..    1067    1084 ..    1064    1091 .. 0.83
  19 !   29.0   0.0   4.2e-10   9.5e-07       2      31 ..    1093    1123 ..    1092    1124 .. 0.94
  20 !   27.0   0.0   1.9e-09   4.2e-06       2      32 .]    1126    1157 ..    1125    1157 .. 0.95
  21 !   16.8   0.0     3e-06    0.0067       3      31 ..    1160    1189 ..    1158    1190 .. 0.91
  22 !   17.6   0.0   1.7e-06    0.0039       2      32 .]    1192    1223 ..    1191    1223 .. 0.93
  23 !    7.9   0.0     0.002       4.5       8      27 ..    1231    1251 ..    1229    1262 .. 0.73
  24 !    9.2   0.0   0.00077       1.7       4      26 ..    1261    1284 ..    1258    1285 .. 0.93
  25 !   11.5   0.0   0.00014      0.32       5      28 ..    1291    1315 ..    1289    1318 .. 0.90
  26 !    8.3   0.0    0.0015       3.3       9      31 ..    1324    1347 ..    1320    1348 .. 0.87
  27 !   10.6   0.0   0.00028      0.62       5      28 ..    1354    1378 ..    1352    1382 .. 0.91
  28 !   16.5   0.0   3.7e-06    0.0083       1      31 [.    1383    1414 ..    1383    1415 .. 0.93
  29 !   11.9   0.0   0.00011      0.25       3      28 ..    1419    1448 ..    1418    1450 .. 0.84
  30 !   23.7   0.0   2.1e-08   4.6e-05       1      29 [.    1450    1479 ..    1450    1482 .. 0.91
  31 !   20.6   0.0   1.9e-07   0.00043       2      31 ..    1484    1513 ..    1483    1514 .. 0.82
  32 !   22.2   0.0   5.8e-08   0.00013       2      31 ..    1516    1546 ..    1515    1547 .. 0.96
  33 !   11.6   0.0   0.00014      0.31       3      31 ..    1550    1579 ..    1549    1580 .. 0.91
  34 ?    0.6   0.0       0.4   8.9e+02       2      21 ..    1582    1601 ..    1581    1617 .. 0.82

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 7.1
                 SBBHHHHHH CS
         Ank   2 GnTPLHlAa 10 
                 G+T+L lA 
  EEA22776.1 261 GWTALELAK 269
                 999998863 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 7.6
                 HHHHHHTT.HHHHHHHH.TTTS CS
         Ank   7 HlAatngk.kriiklLL.hGAn 26 
                  lA++ g+ k++++ L+  GAn
  EEA22776.1 554 ILASRVGDdKEVCR-LVeIGAN 574
                 57886666699999.7744876 PP

  == domain 3  score: 9.3 bits;  conditional E-value: 0.00073
                 BBHHHHHH..HHTTHHHHHHHH..TT CS
         Ank   3 nTPLHlAa..tngkkriiklLL..hG 24 
                 +T+LH+A+  +++  r+++ L+  +G
  EEA22776.1 583 WTALHYASwlCYD--RVVETLIgsSG 606
                 6******977566..8******6334 PP

  == domain 4  score: 27.4 bits;  conditional E-value: 1.4e-09
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlnald 31 
                 G ++LHlA+ +g+  i+ lLL +GA++n++d
  EEA22776.1 614 GQSALHLASERGSQKIVGLLLaRGADPNIQD 644
                 89*******99**********99*******9 PP

  == domain 5  score: 26.4 bits;  conditional E-value: 2.7e-09
                 SBBHHHHHHHHTTHHHHH.HHHTTTSTTCBT CS
         Ank   2 GnTPLHlAatngkkriik.lLLhGAnlnald 31 
                 G T+LH+Aa++  ++i++ lLL GA++n++d
  EEA22776.1 647 GQTALHRAAWGSCTQIVEqLLLGGADPNIQD 677
                 99*******7666****8466677******9 PP

  == domain 6  score: 14.6 bits;  conditional E-value: 1.5e-05
                 SBBHHHHHHHHTTHHHHHHHH.TTT.STTC CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGA.nlna 29 
                 G T+LH+Aa++ + + ++ LL +GA nl +
  EEA22776.1 680 GKTALHVAAQYSHIETVQ-LLaNGAsNLYI 708
                 89****************.66699626655 PP

  == domain 7  score: 15.5 bits;  conditional E-value: 8e-06
                 TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hGAnlnald 31 
                 +Gn PLH+Aa  g+  i++lLL  GA+l  l+
  EEA22776.1 712 HGNHPLHVAAEAGDIIILHLLLdAGADLSVLN 743
                 69********99999999****66***98876 PP

  == domain 8  score: 8.6 bits;  conditional E-value: 0.0012
                 TSBBHHHHHHHHTTHHHHHHHH CS
         Ank   1 dGnTPLHlAatngkkriiklLL 22 
                 dG+ +LHlAa +g+  i+++L 
  EEA22776.1 745 DGWRALHLAAARGHDAIVRMLR 766
                 7999******99**99999884 PP

  == domain 9  score: 0.3 bits;  conditional E-value: 0.51
                 HHHHHH.TT.TSTTCBT CS
         Ank  17 iiklLL.hG.Anlnald 31 
                 +i++LL +  A++ ++d
  EEA22776.1 792 VIHELLrDNeADICITD 808
                 899***8646***9998 PP

  == domain 10  score: 10.1 bits;  conditional E-value: 0.0004
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlnald 31 
                 G+ +LH+Aa +g++ +++ LL +G +++++d
  EEA22776.1 811 GRLALHRAAEGGSEIVARQLLeKGVDIDSKD 841
                 6669*****7676777779**99*****998 PP

  == domain 11  score: 25.0 bits;  conditional E-value: 8.1e-09
                 BBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   3 nTPLHlAatngkkriiklLL.hGAnlnald 31 
                 +TPL +Aa+ng++ +++lLL +GA++n++d
  EEA22776.1 845 RTPLSWAAQNGHEAVVRLLLeKGADPNSKD 874
                 7*******************99******98 PP

  == domain 12  score: 11.9 bits;  conditional E-value: 0.00011
                 BBHHHHHHHHTTHHHHHHHH.TTTS CS
         Ank   3 nTPLHlAatngkkriiklLL.hGAn 26 
                  TPL +Aa ng++  i+lL+ +GAn
  EEA22776.1 878 KTPLWWAAGNGHEAAIRLLIeNGAN 902
                 5*******99**********99**9 PP

  == domain 13  score: 6.4 bits;  conditional E-value: 0.0061
                 TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hGAnlnald 31 
                 +G+T   +Aa  g +++++ LL +G +++++d
  EEA22776.1 909 YGRTLIWWAAEDGYENVVRQLLeYG-DIDLKD 939
                 699*******666699******99*.**9998 PP

  == domain 14  score: 8.3 bits;  conditional E-value: 0.0015
                 HHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   8 lAatngkkriiklLL.hGAnlna 29 
                 +Aa ng++ +++lL+ ++A++n+
  EEA22776.1 947 RAAENGHETVVQLLVaNSADPNS 969
                 6999***********989***95 PP

  == domain 15  score: 5.2 bits;  conditional E-value: 0.015
                  BHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    4 TPLHlAatngkkriiklLL.hGAnlnald 31  
                  T L +Aa ng+  +++ LL +G ++ ++d
  EEA22776.1  972 TMLSWAAENGHDAVVRKLLeNGTDPMLKD 1000
                  66889**************99****9998 PP

  == domain 16  score: 19.5 bits;  conditional E-value: 4.2e-07
                  SBBHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAnlna 29  
                  G T L lAa ng++ +++lLL h+A++n+
  EEA22776.1 1003 GQTSLWLAAKNGHEAVVRLLLkHRADPNS 1031
                  9999***********************95 PP

  == domain 17  score: 13.9 bits;  conditional E-value: 2.5e-05
                  BHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank    4 TPLHlAatngkkriiklLL.hGAnlna 29  
                  +PL +Aa ng k +++lLL +GA++n+
  EEA22776.1 1036 SPLRRAAENGYKAVVRLLLeSGADPNS 1062
                  79999**9***********99****95 PP

  == domain 18  score: 2.6 bits;  conditional E-value: 0.092
                  HHHHTTHHHHHHHH.TTT CS
         Ank    9 AatngkkriiklLL.hGA 25  
                  Aa ng+  +++lL+ +GA
  EEA22776.1 1067 AAKNGHIAVVRLLVeNGA 1084
                  89999*********8897 PP

  == domain 19  score: 29.0 bits;  conditional E-value: 4.2e-10
                  SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAnlnald 31  
                  G+TPLH+Aa  g++++i+lLL +GA++ ++d
  EEA22776.1 1093 GWTPLHMAAESGHEDVIRLLLeKGACIESKD 1123
                  9********99**********99****9887 PP

  == domain 20  score: 27.0 bits;  conditional E-value: 1.9e-09
                  SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAnlnaldn 32  
                  G+TPL +A++ng++ +i+lLL +GA+l ++d+
  EEA22776.1 1126 GRTPLWWASRNGHEAVIQLLLkNGAELCIKDD 1157
                  9********************99******995 PP

  == domain 21  score: 16.8 bits;  conditional E-value: 3e-06
                  BBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    3 nTPLHlAatngkkriiklLL.hGAnlnald 31  
                  +TPL +Aa ng++++++lLL + A++ ++d
  EEA22776.1 1160 WTPLQMAAENGHEDVAQLLLeNAADVESKD 1189
                  8*******************777**99988 PP

  == domain 22  score: 17.6 bits;  conditional E-value: 1.7e-06
                  SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAnlnaldn 32  
                  G TPL  Aa ng++ i++lL+ +GAn+ ++d+
  EEA22776.1 1192 GQTPLRKAAENGHEGIVRLLIkNGANPMSKDK 1223
                  99*******999999******99****99985 PP

  == domain 23  score: 7.9 bits;  conditional E-value: 0.002
                  HHHHHTTHHHHHHHH.TTTST CS
         Ank    8 lAatngkkriiklLL.hGAnl 27  
                   A+ ng+k +++lLL +G ++
  EEA22776.1 1231 SAVKNGHKAVVQLLLeNGPDP 1251
                  4679***********989553 PP

  == domain 24  score: 9.2 bits;  conditional E-value: 0.00077
                  BHHHHHHHHTTHHHHHHHH.TTTS CS
         Ank    4 TPLHlAatngkkriiklLL.hGAn 26  
                  T L +A+ ng++ i++lLL +GA+
  EEA22776.1 1261 TLLVWASENGHEAIVRLLLeKGAD 1284
                  88999**************99*98 PP

  == domain 25  score: 11.5 bits;  conditional E-value: 0.00014
                  HHHHHHHHTTHHHHHHHH.TTTSTT CS
         Ank    5 PLHlAatngkkriiklLL.hGAnln 28  
                  PL +Aa ng++ +++lLL ++ ++n
  EEA22776.1 1291 PLWYAAENGHEGVVRLLLkNSVDPN 1315
                  9*****999999******7789998 PP

  == domain 26  score: 8.3 bits;  conditional E-value: 0.0015
                  HHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    9 AatngkkriiklLL.hGAnlnald 31  
                  A+ ng++++++lLL +GA++ + d
  EEA22776.1 1324 AVDNGHLEVTRLLLkNGADVESED 1347
                  6789**********99***98766 PP

  == domain 27  score: 10.6 bits;  conditional E-value: 0.00028
                  HHHHHHHHTTHHHHHHHH.TTTSTT CS
         Ank    5 PLHlAatngkkriiklLL.hGAnln 28  
                  PL +Aa  g++ +++ LL +GA++ 
  EEA22776.1 1354 PLWIAAEKGNEAVVRILLeNGADPR 1378
                  9*****99**********99***94 PP

  == domain 28  score: 16.5 bits;  conditional E-value: 3.7e-06
                  TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    1 dGnTPLHlAatngkkriiklLL.hGAnlnald 31  
                  +G+T+L  Aa+ g++ +++lLL +G ++ ++d
  EEA22776.1 1383 NGDTALSSAANKGHEPVVRLLLeNGTDIELTD 1414
                  7*********************99*9998877 PP

  == domain 29  score: 11.9 bits;  conditional E-value: 0.00011
                  BBHHHHHHHHTTHHHHHHHH.TTTS..T.T CS
         Ank    3 nTPLHlAatngkkriiklLL.hGAn..l.n 28  
                   TPL +A t+ ++ +++lLL +GAn  l n
  EEA22776.1 1419 KTPLWWATTREHAAVTRLLLeNGANakLkN 1448
                  5*******************99*9844445 PP

  == domain 30  score: 23.7 bits;  conditional E-value: 2.1e-08
                  TSBBHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank    1 dGnTPLHlAatngkkriiklLL.hGAnlna 29  
                  +G+TPLH Aa++g++ +++lL+ +GA++ +
  EEA22776.1 1450 HGDTPLHDAARYGNEAVVRLLIeNGAEIES 1479
                  69********************99**9865 PP

  == domain 31  score: 20.6 bits;  conditional E-value: 1.9e-07
                  SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAnlnald 31  
                  G TPLH+A  ++  +i+k LL +GAn+ ++d
  EEA22776.1 1484 GETPLHCAT-GNRRDIVKVLLeNGANIKSKD 1513
                  99*****55.55566******99***97776 PP

  == domain 32  score: 22.2 bits;  conditional E-value: 5.8e-08
                  SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAnlnald 31  
                  G TPL +Aa++g++  i+lLL +GA++n++d
  EEA22776.1 1516 GQTPLQRAAREGNEAAIRLLLeKGADPNSKD 1546
                  99*******************99******98 PP

  == domain 33  score: 11.6 bits;  conditional E-value: 0.00014
                  BBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    3 nTPLHlAatngkkriiklLL.hGAnlnald 31  
                   TPL +A  ng++ + +lL+ +GA++ ++d
  EEA22776.1 1550 KTPLWWATGNGHVAVMRLLIeNGADPKLKD 1579
                  5*****999999********99***98777 PP

  == domain 34  score: 0.6 bits;  conditional E-value: 0.4
                  SBBHHHHHHHHTTHHHHHHH CS
         Ank    2 GnTPLHlAatngkkriiklL 21  
                  G+T   +Aa ng+k  ++lL
  EEA22776.1 1582 GRTLMWWAAENGHKTAVQLL 1601
                  788888*******9999976 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1       2.5   5.7e+03       3       9 ..     583     589 ..     581     594 .. 0.90
   2 !   13.7   0.0   3.1e-05     0.069       2      31 .]     614     642 ..     613     642 .. 0.97
   3 !   11.3   0.0   0.00019      0.42       2      31 .]     647     675 ..     646     675 .. 0.94
   4 !    9.7   0.0   0.00064       1.4       2      26 ..     680     703 ..     679     708 .. 0.82
   5 !   18.9   0.3   6.3e-07    0.0014       1      30 [.     712     740 ..     712     741 .. 0.94
   6 !   11.3   0.0   0.00019      0.42       1      26 [.     745     769 ..     745     773 .. 0.88
   7 ?    1.2   0.0      0.37   8.2e+02       3      29 ..     778     804 ..     776     806 .. 0.85
   8 !   14.9   0.0   1.3e-05      0.03       1      30 [.     810     838 ..     810     839 .. 0.95
   9 !   22.5   0.0   4.3e-08   9.5e-05       2      30 ..     844     871 ..     843     872 .. 0.95
  10 !   14.6   0.0   1.7e-05     0.037       3      28 ..     878     902 ..     876     904 .. 0.92
  11 !    9.7   0.0   0.00065       1.5       1      28 [.     909     936 ..     909     938 .. 0.89
  12 !   10.0   0.0   0.00049       1.1       5      30 ..     944     968 ..     940     969 .. 0.88
  13 !   14.4   0.0   1.8e-05     0.041       3      29 ..     971     996 ..     970     998 .. 0.94
  14 !   18.1   0.0   1.2e-06    0.0026       2      30 ..    1003    1030 ..    1002    1031 .. 0.96
  15 !   11.9   0.0   0.00012      0.27       4      30 ..    1036    1061 ..    1035    1062 .. 0.95
  16 !    8.5   0.0    0.0015       3.4       5      27 ..    1063    1084 ..    1060    1085 .. 0.88
  17 !   23.1   0.0   2.8e-08   6.4e-05       2      27 ..    1093    1117 ..    1092    1118 .. 0.94
  18 !   18.3   0.0   9.9e-07    0.0022       1      29 [.    1125    1152 ..    1125    1154 .. 0.92
  19 !   16.9   0.0   2.8e-06    0.0064       2      29 ..    1159    1185 ..    1158    1187 .. 0.92
  20 !   16.1   0.0   5.3e-06     0.012       1      29 [.    1191    1218 ..    1191    1219 .. 0.94
  21 !    7.7   0.0    0.0029       6.6       9      29 ..    1232    1251 ..    1227    1252 .. 0.90
  22 !   14.6   0.0   1.7e-05     0.037       2      28 ..    1259    1284 ..    1258    1286 .. 0.94
  23 !   13.0   0.0   5.5e-05      0.12       3      30 ..    1289    1315 ..    1288    1316 .. 0.93
  24 !    6.8   0.0    0.0054        12       6      29 ..    1321    1343 ..    1317    1345 .. 0.86
  25 !   14.3   0.0     2e-05     0.044       2      30 ..    1351    1378 ..    1350    1379 .. 0.91
  26 !   14.6   0.0   1.6e-05     0.036       1      30 [.    1383    1411 ..    1383    1412 .. 0.94
  27 ?    4.6   0.0     0.028        63       3      28 ..    1419    1443 ..    1417    1446 .. 0.91
  28 !   18.7   0.0   7.3e-07    0.0016       1      29 [.    1450    1477 ..    1450    1479 .. 0.94
  29 !   16.3   0.0   4.5e-06      0.01       2      29 ..    1484    1509 ..    1483    1511 .. 0.91
  30 !   21.0   0.0   1.3e-07   0.00029       2      30 ..    1516    1543 ..    1515    1544 .. 0.96
  31 !   14.9   0.0   1.3e-05     0.028       3      29 ..    1550    1575 ..    1548    1577 .. 0.93
  32 !   10.1   0.0   0.00047       1.1       2      27 ..    1582    1606 ..    1581    1608 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 2.5
       Ank_3   3 etpLhlA 9  
                 +t+Lh+A
  EEA22776.1 583 WTALHYA 589
                 9****99 PP

  == domain 2  score: 13.7 bits;  conditional E-value: 3.1e-05
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvna 31 
                 G+++LhlA + g+ +iv +Ll  +gad+n+
  EEA22776.1 614 GQSALHLASERGSQKIVGLLLA-RGADPNI 642
                 99********************.*****97 PP

  == domain 3  score: 11.3 bits;  conditional E-value: 0.00019
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvna 31 
                 G+t+Lh+Aa   ++ iv+ Ll   gad+n+
  EEA22776.1 647 GQTALHRAAWGSCTQIVEQLLL-GGADPNI 675
                 9********999999*******.9****97 PP

  == domain 4  score: 9.7 bits;  conditional E-value: 0.00064
       Ank_3   2 GetpLhlAarsgnleivkfLlenkg 26 
                 G t+Lh+Aa + ++e v++L +   
  EEA22776.1 680 GKTALHVAAQYSHIETVQLLAN-GA 703
                 89*************8888877.44 PP

  == domain 5  score: 18.9 bits;  conditional E-value: 6.3e-07
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvn 30 
                 +G+ pLh+Aa++g++ i+++Ll+  gad+ 
  EEA22776.1 712 HGNHPLHVAAEAGDIIILHLLLD-AGADLS 740
                 79*********************.8***86 PP

  == domain 6  score: 11.3 bits;  conditional E-value: 0.00019
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkg 26 
                 +G+ +LhlAa  g+ +iv++L e k 
  EEA22776.1 745 DGWRALHLAAARGHDAIVRMLRE-KD 769
                 699*****************987.55 PP

  == domain 7  score: 1.2 bits;  conditional E-value: 0.37
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadv 29 
                 + +L  Aa+ g   +++ Ll+ + ad+
  EEA22776.1 778 WKLLQSAAKGGLEWVIHELLRDNEADI 804
                 67888999999999*******889987 PP

  == domain 8  score: 14.9 bits;  conditional E-value: 1.3e-05
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvn 30 
                 +G+ +Lh+Aa+ g+  +++ Lle kg+d++
  EEA22776.1 810 EGRLALHRAAEGGSEIVARQLLE-KGVDID 838
                 5999*******************.9***97 PP

  == domain 9  score: 22.5 bits;  conditional E-value: 4.3e-08
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvn 30 
                  +tpL +Aa +g+ ++v++Lle kgad+n
  EEA22776.1 844 RRTPLSWAAQNGHEAVVRLLLE-KGADPN 871
                 69********************.9****9 PP

  == domain 10  score: 14.6 bits;  conditional E-value: 1.7e-05
       Ank_3   3 etpLhlAarsgnleivkfLlenkgad 28 
                  tpL +Aa +g+ + +++L+e +ga+
  EEA22776.1 878 KTPLWWAAGNGHEAAIRLLIE-NGAN 902
                 69*******************.8998 PP

  == domain 11  score: 9.7 bits;  conditional E-value: 0.00065
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgad 28 
                 +G+t++ +Aa+ g  ++v+ Lle   +d
  EEA22776.1 909 YGRTLIWWAAEDGYENVVRQLLEYGDID 936
                 79*********************66665 PP

  == domain 12  score: 10.0 bits;  conditional E-value: 0.00049
       Ank_3   5 pLhlAarsgnleivkfLlenkgadvn 30 
                 +L +Aa++g+ ++v++L+  + ad+n
  EEA22776.1 944 LLRRAAENGHETVVQLLVA-NSADPN 968
                 4559***************.8****9 PP

  == domain 13  score: 14.4 bits;  conditional E-value: 1.8e-05
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadv 29 
                 +t+L +Aa++g+ ++v+ Lle +g d+
  EEA22776.1 971 QTMLSWAAENGHDAVVRKLLE-NGTDP 996
                 79*******************.89997 PP

  == domain 14  score: 18.1 bits;  conditional E-value: 1.2e-06
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                  G+t L lAa++g+ ++v++Ll+ + ad+n
  EEA22776.1 1003 GQTSLWLAAKNGHEAVVRLLLK-HRADPN 1030
                  9*********************.9***99 PP

  == domain 15  score: 11.9 bits;  conditional E-value: 0.00012
       Ank_3    4 tpLhlAarsgnleivkfLlenkgadvn 30  
                  +pL +Aa++g  ++v++Lle  gad+n
  EEA22776.1 1036 SPLRRAAENGYKAVVRLLLE-SGADPN 1061
                  89******************.9****9 PP

  == domain 16  score: 8.5 bits;  conditional E-value: 0.0015
       Ank_3    5 pLhlAarsgnleivkfLlenkga 27  
                   L +Aa++g++++v++L+e +ga
  EEA22776.1 1063 GLNFAAKNGHIAVVRLLVE-NGA 1084
                  5899***************.786 PP

  == domain 17  score: 23.1 bits;  conditional E-value: 2.8e-08
       Ank_3    2 GetpLhlAarsgnleivkfLlenkga 27  
                  G+tpLh+Aa+sg+ +++++Lle kga
  EEA22776.1 1093 GWTPLHMAAESGHEDVIRLLLE-KGA 1117
                  9*********************.775 PP

  == domain 18  score: 18.3 bits;  conditional E-value: 9.9e-07
       Ank_3    1 nGetpLhlAarsgnleivkfLlenkgadv 29  
                  +G+tpL +A r+g+ +++++Ll+ +ga++
  EEA22776.1 1125 EGRTPLWWASRNGHEAVIQLLLK-NGAEL 1152
                  69*********************.89976 PP

  == domain 19  score: 16.9 bits;  conditional E-value: 2.8e-06
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadv 29  
                   +tpL +Aa++g+ +++++Lle + adv
  EEA22776.1 1159 DWTPLQMAAENGHEDVAQLLLE-NAADV 1185
                  69********************.89998 PP

  == domain 20  score: 16.1 bits;  conditional E-value: 5.3e-06
       Ank_3    1 nGetpLhlAarsgnleivkfLlenkgadv 29  
                  +G+tpL  Aa++g+  iv++L++ +ga++
  EEA22776.1 1191 EGQTPLRKAAENGHEGIVRLLIK-NGANP 1218
                  69*********************.89986 PP

  == domain 21  score: 7.7 bits;  conditional E-value: 0.0029
       Ank_3    9 AarsgnleivkfLlenkgadv 29  
                  A+++g+ ++v++Lle +g+d+
  EEA22776.1 1232 AVKNGHKAVVQLLLE-NGPDP 1251
                  99*************.8*997 PP

  == domain 22  score: 14.6 bits;  conditional E-value: 1.7e-05
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgad 28  
                   +t+L +A ++g+ +iv++Lle kgad
  EEA22776.1 1259 IRTLLVWASENGHEAIVRLLLE-KGAD 1284
                  59********************.9*99 PP

  == domain 23  score: 13.0 bits;  conditional E-value: 5.5e-05
       Ank_3    3 etpLhlAarsgnleivkfLlenkgadvn 30  
                  + pL +Aa++g+  +v++Ll+ + +d+n
  EEA22776.1 1289 NWPLWYAAENGHEGVVRLLLK-NSVDPN 1315
                  569******************.8***99 PP

  == domain 24  score: 6.8 bits;  conditional E-value: 0.0054
       Ank_3    6 LhlAarsgnleivkfLlenkgadv 29  
                  L  A+ +g+le+ ++Ll+ +gadv
  EEA22776.1 1321 LLGAVDNGHLEVTRLLLK-NGADV 1343
                  55599*************.8***8 PP

  == domain 25  score: 14.3 bits;  conditional E-value: 2e-05
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                   + pL +Aa+ gn ++v+ Lle +gad++
  EEA22776.1 1351 KRRPLWIAAEKGNEAVVRILLE-NGADPR 1378
                  578*******************.8***96 PP

  == domain 26  score: 14.6 bits;  conditional E-value: 1.6e-05
       Ank_3    1 nGetpLhlAarsgnleivkfLlenkgadvn 30  
                  nG t+L  Aa  g+ ++v++Lle +g d+ 
  EEA22776.1 1383 NGDTALSSAANKGHEPVVRLLLE-NGTDIE 1411
                  799********************.8**985 PP

  == domain 27  score: 4.6 bits;  conditional E-value: 0.028
       Ank_3    3 etpLhlAarsgnleivkfLlenkgad 28  
                   tpL +A    + ++ ++Lle +ga+
  EEA22776.1 1419 KTPLWWATTREHAAVTRLLLE-NGAN 1443
                  7********************.8998 PP

  == domain 28  score: 18.7 bits;  conditional E-value: 7.3e-07
       Ank_3    1 nGetpLhlAarsgnleivkfLlenkgadv 29  
                  +G tpLh Aar+gn ++v++L+e +ga++
  EEA22776.1 1450 HGDTPLHDAARYGNEAVVRLLIE-NGAEI 1477
                  699********************.89987 PP

  == domain 29  score: 16.3 bits;  conditional E-value: 4.5e-06
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadv 29  
                  GetpLh+A  + +   vk Lle +ga++
  EEA22776.1 1484 GETPLHCATGNRRDI-VKVLLE-NGANI 1509
                  9*****999999996.******.8**98 PP

  == domain 30  score: 21.0 bits;  conditional E-value: 1.3e-07
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                  G+tpL +Aar gn + +++Lle kgad+n
  EEA22776.1 1516 GQTPLQRAAREGNEAAIRLLLE-KGADPN 1543
                  9*********************.9****9 PP

  == domain 31  score: 14.9 bits;  conditional E-value: 1.3e-05
       Ank_3    3 etpLhlAarsgnleivkfLlenkgadv 29  
                   tpL +A  +g+++++++L+e +gad+
  EEA22776.1 1550 KTPLWWATGNGHVAVMRLLIE-NGADP 1575
                  69*******************.8***8 PP

  == domain 32  score: 10.1 bits;  conditional E-value: 0.00047
       Ank_3    2 GetpLhlAarsgnleivkfLlenkga 27  
                  G+t++ +Aa++g+ + v++L + +g+
  EEA22776.1 1582 GRTLMWWAAENGHKTAVQLLKD-YGI 1606
                  9**************9999988.887 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0       1.4   3.2e+03      47      56 .]     259     268 ..     259     268 .. 0.91
   2 !    6.0   0.0     0.007        16       1      36 [.     568     602 ..     568     612 .. 0.81
   3 !   25.8   0.0   4.4e-09   9.8e-06      15      53 ..     613     651 ..     606     651 .. 0.92
   4 !   41.4   0.0   5.3e-14   1.2e-10       1      56 []     633     687 ..     633     687 .. 0.98
   5 !   28.6   1.8   5.5e-10   1.2e-06       1      56 []     698     753 ..     698     753 .. 0.97
   6 !   14.6   0.4   1.4e-05     0.032       1      35 [.     732     765 ..     732     784 .. 0.82
   7 !    9.1   0.0   0.00076       1.7      21      56 .]     782     818 ..     764     818 .. 0.78
   8 !   22.5   0.0   4.6e-08    0.0001       1      53 [.     797     848 ..     796     849 .. 0.94
   9 !   27.5   0.0   1.2e-09   2.8e-06       1      53 [.     830     881 ..     830     881 .. 0.95
  10 !   22.1   0.0     6e-08   0.00013       1      52 [.     863     913 ..     863     914 .. 0.97
  11 !   10.2   0.0   0.00034      0.76       1      51 [.     896     944 ..     896     949 .. 0.92
  12 !   28.8   0.0   4.9e-10   1.1e-06       2      53 ..     961    1007 ..     959    1010 .. 0.89
  13 !   11.2   0.0   0.00016      0.36      16      43 ..    1003    1030 ..    1003    1038 .. 0.92
  14 !    8.5   0.0    0.0011       2.6       1      43 [.    1022    1061 ..    1022    1063 .. 0.91
  15 !   28.4   0.1   6.3e-10   1.4e-06      18      56 .]    1062    1100 ..    1053    1100 .. 0.93
  16 !   16.8   0.0   2.9e-06    0.0065      13      53 ..    1091    1130 ..    1089    1130 .. 0.91
  17 !   19.3   0.0   4.7e-07     0.001       9      56 .]    1119    1166 ..    1112    1166 .. 0.89
  18 !   23.4   0.0   2.4e-08   5.4e-05       1      52 [.    1178    1228 ..    1177    1228 .. 0.92
  19 ?    2.0   0.0      0.12   2.7e+02      23      42 ..    1232    1251 ..    1231    1252 .. 0.93
  20 !    9.3   0.0   0.00065       1.5       1      41 [.    1244    1284 ..    1244    1289 .. 0.75
  21 ?    5.3   0.0     0.012        26      19      43 ..    1291    1315 ..    1285    1319 .. 0.88
  22 !   10.5   0.0   0.00027      0.61       1      42 [.    1307    1343 ..    1306    1347 .. 0.90
  23 !   18.5   0.0     8e-07    0.0018       1      53 [.    1336    1388 ..    1336    1391 .. 0.90
  24 !   24.6   0.0     1e-08   2.3e-05       1      53 [.    1370    1422 ..    1370    1423 .. 0.97
  25 !   27.3   0.3   1.5e-09   3.3e-06       1      54 [.    1403    1456 ..    1403    1456 .. 0.93
  26 !   24.1   0.2   1.5e-08   3.3e-05       1      54 [.    1437    1489 ..    1437    1491 .. 0.93
  27 !   27.8   0.0   9.7e-10   2.2e-06       1      56 []    1470    1523 ..    1470    1523 .. 0.86
  28 !   27.2   0.0   1.5e-09   3.5e-06       1      53 [.    1535    1586 ..    1535    1586 .. 0.97

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 1.4
       Ank_5  47 srGltaldlA 56 
                 srG+tal+lA
  EEA22776.1 259 SRGWTALELA 268
                 68******99 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.007
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl 36 
                 L+e g a+  ++d++  t+Lh+A++  + +vv+ L+
  EEA22776.1 568 LVEIG-ANSSWEDERTWTALHYASWLCYDRVVETLI 602
                 67777.88889999999********88888887777 PP

  == domain 3  score: 25.8 bits;  conditional E-value: 4.4e-09
       Ank_5  15 ggntpLhvAakygaadvvrlLlargadlnltdsrGltal 53 
                  g+++Lh+A+++g++ +v lLlargad+n++ds G+tal
  EEA22776.1 613 LGQSALHLASERGSQKIVGLLLARGADPNIQDSKGQTAL 651
                 5789*********************************98 PP

  == domain 4  score: 41.4 bits;  conditional E-value: 5.3e-14
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 Ll++g ad+n +d +g+t+Lh Aa++ + ++v+ Ll  gad+n++ds G+tal++A
  EEA22776.1 633 LLARG-ADPNIQDSKGQTALHRAAWGSCTQIVEQLLLGGADPNIQDSVGKTALHVA 687
                 89999.************************************************98 PP

  == domain 5  score: 28.6 bits;  conditional E-value: 5.5e-10
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 Ll++g  ++  +d +gn+pLhvAa++g   ++ lLl+ gadl + +s+G+ al+lA
  EEA22776.1 698 LLANGASNLYISDCHGNHPLHVAAEAGDIIILHLLLDAGADLSVLNSDGWRALHLA 753
                 899999999********************************************998 PP

  == domain 6  score: 14.6 bits;  conditional E-value: 1.4e-05
       Ank_5   1 Llehg.padvnrldgggntpLhvAakygaadvvrlL 35 
                 Ll++g + +v ++dg+   +Lh+Aa +g+  +vr+L
  EEA22776.1 732 LLDAGaDLSVLNSDGW--RALHLAAARGHDAIVRML 765
                 89***67777777666..****************99 PP

  == domain 7  score: 9.1 bits;  conditional E-value: 0.00076
       Ank_5  21 hvAakygaadvvrlLl..argadlnltdsrGltaldlA 56 
                   +a +g +++v+  l  +++ad+ +tds+G++al+ A
  EEA22776.1 782 Q-SAAKGGLEWVIHELlrDNEADICITDSEGRLALHRA 818
                 4.4555999*************************9876 PP

  == domain 8  score: 22.5 bits;  conditional E-value: 4.6e-08
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltal 53 
                 L ++  ad++ +d +g ++Lh Aa++g+  v+r Ll+ g+d++ +d + +t+l
  EEA22776.1 797 LRDNE-ADICITDSEGRLALHRAAEGGSEIVARQLLEKGVDIDSKDRNRRTPL 848
                 45666.9***************************************999**98 PP

  == domain 9  score: 27.5 bits;  conditional E-value: 1.2e-09
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltal 53 
                 Lle+g +d++ +d+++ tpL +Aa +g+  vvrlLl+ gad+n +d   +t+l
  EEA22776.1 830 LLEKG-VDIDSKDRNRRTPLSWAAQNGHEAVVRLLLEKGADPNSKDHKDKTPL 881
                 89999.9**************************************98888886 PP

  == domain 10  score: 22.1 bits;  conditional E-value: 6e-08
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGlta 52 
                 Lle+g ad+n +d +  tpL +Aa +g+   +rlL+++ga+++ +d++G+t+
  EEA22776.1 863 LLEKG-ADPNSKDHKDKTPLWWAAGNGHEAAIRLLIENGANYKSKDEYGRTL 913
                 89999.********************************************97 PP

  == domain 11  score: 10.2 bits;  conditional E-value: 0.00034
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGlt 51 
                 L+e+g a+   +d++g t + +Aa+ g+ +vvr Ll +  d++l+d++G++
  EEA22776.1 896 LIENG-ANYKSKDEYGRTLIWWAAEDGYENVVRQLL-EYGDIDLKDEYGPL 944
                 78888.888899************************.999********965 PP

  == domain 12  score: 28.8 bits;  conditional E-value: 4.9e-10
       Ank_5    2 lehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltal 53  
                  +++ +ad+n ++    t L +Aa++g+  vvr+Ll++g d++l+ds+G+t l
  EEA22776.1  961 VAN-SADPNSSQ----TMLSWAAENGHDAVVRKLLENGTDPMLKDSSGQTSL 1007
                  444.59999998....*********************************987 PP

  == domain 13  score: 11.2 bits;  conditional E-value: 0.00016
       Ank_5   16 gntpLhvAakygaadvvrlLlargadln 43  
                  g+t L +Aak+g+  vvrlLl+++ad+n
  EEA22776.1 1003 GQTSLWLAAKNGHEAVVRLLLKHRADPN 1030
                  679999********************98 PP

  == domain 14  score: 8.5 bits;  conditional E-value: 0.0011
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadln 43  
                  Ll+h+ ad+n +  +  +pL  Aa++g+  vvrlLl+ gad+n
  EEA22776.1 1022 LLKHR-ADPNSNGVD--SPLRRAAENGYKAVVRLLLESGADPN 1061
                  89999.888887777..*********************99998 PP

  == domain 15  score: 28.4 bits;  conditional E-value: 6.3e-10
       Ank_5   18 tpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56  
                  + L++Aak+g+  vvrlL+++ga   l+d+rG+t+l++A
  EEA22776.1 1062 SGLNFAAKNGHIAVVRLLVENGAGHSLKDDRGWTPLHMA 1100
                  78***********************************98 PP

  == domain 16  score: 16.8 bits;  conditional E-value: 2.9e-06
       Ank_5   13 dgggntpLhvAakygaadvvrlLlargadlnltdsrGltal 53  
                  d+g+ tpLh+Aa+ g+ dv+rlLl+ ga +  +d +G+t+l
  EEA22776.1 1091 DRGW-TPLHMAAESGHEDVIRLLLEKGACIESKDHEGRTPL 1130
                  4455.**********************************97 PP

  == domain 17  score: 19.3 bits;  conditional E-value: 4.7e-07
       Ank_5    9 vnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56  
                  +  +d +g tpL +A+++g+  v++lLl++ga l ++d++ +t+l++A
  EEA22776.1 1119 IESKDHEGRTPLWWASRNGHEAVIQLLLKNGAELCIKDDHDWTPLQMA 1166
                  566788999*************************************98 PP

  == domain 18  score: 23.4 bits;  conditional E-value: 2.4e-08
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGlta 52  
                  Lle+  adv  +d++g+tpL  Aa++g+  +vrlL+++ga+++ +d+   t+
  EEA22776.1 1178 LLENA-ADVESKDREGQTPLRKAAENGHEGIVRLLIKNGANPMSKDKFDGTP 1228
                  67775.9**************************************9986665 PP

  == domain 19  score: 2.0 bits;  conditional E-value: 0.12
       Ank_5   23 AakygaadvvrlLlargadl 42  
                  A+k+g+  vv+lLl++g d+
  EEA22776.1 1232 AVKNGHKAVVQLLLENGPDP 1251
                  99***************997 PP

  == domain 20  score: 9.3 bits;  conditional E-value: 0.00065
       Ank_5    1 Llehg.padvnrldgggntpLhvAakygaadvvrlLlargad 41  
                  Lle+g +  + + ++ + t L +A+++g+  +vrlLl+ gad
  EEA22776.1 1244 LLENGpDPGPRADNNIR-TLLVWASENGHEAIVRLLLEKGAD 1284
                  56666444444444444.*******************99998 PP

  == domain 21  score: 5.3 bits;  conditional E-value: 0.012
       Ank_5   19 pLhvAakygaadvvrlLlargadln 43  
                  pL +Aa++g+  vvrlLl++ +d+n
  EEA22776.1 1291 PLWYAAENGHEGVVRLLLKNSVDPN 1315
                  8889****************99998 PP

  == domain 22  score: 10.5 bits;  conditional E-value: 0.00027
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadl 42  
                  Ll++  +d+n+l+     pL  A+ +g+++v rlLl++gad 
  EEA22776.1 1307 LLKNS-VDPNDLQ----RPLLGAVDNGHLEVTRLLLKNGADV 1343
                  56665.9999999....***********************96 PP

  == domain 23  score: 18.5 bits;  conditional E-value: 8e-07
       Ank_5    1 Llehgpadvnrldgggn.tpLhvAakygaadvvrlLlargadlnltdsrGltal 53  
                  Ll++g adv  +d +    pL +Aa++g+  vvr+Ll++gad++ + s+G+tal
  EEA22776.1 1336 LLKNG-ADVESEDYFNKrRPLWIAAEKGNEAVVRILLENGADPRSKHSNGDTAL 1388
                  78888.888888877657***********************************8 PP

  == domain 24  score: 24.6 bits;  conditional E-value: 1e-08
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrG.ltal 53  
                  Lle+g ad+  +  +g t+L  Aa++g+ +vvrlLl++g d+ ltd +G +t+l
  EEA22776.1 1370 LLENG-ADPRSKHSNGDTALSSAANKGHEPVVRLLLENGTDIELTDQNGnKTPL 1422
                  89***.99999999999***********************************97 PP

  == domain 25  score: 27.3 bits;  conditional E-value: 1.5e-09
       Ank_5    1 Llehg.padvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltald 54  
                  Lle+g ++ + +++g++ tpL +A  + +a v rlLl++ga+++l++++G+t+l+
  EEA22776.1 1403 LLENGtDIELTDQNGNK-TPLWWATTREHAAVTRLLLENGANAKLKNAHGDTPLH 1456
                  89***888888888777.***********************************96 PP

  == domain 26  score: 24.1 bits;  conditional E-value: 1.5e-08
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltald 54  
                  Lle+g a+   ++ +g tpLh Aa+yg+  vvrlL+++ga +   + rG+t+l+
  EEA22776.1 1437 LLENG-ANAKLKNAHGDTPLHDAARYGNEAVVRLLIENGAEIESENWRGETPLH 1489
                  89999.88888899999***********************************97 PP

  == domain 27  score: 27.8 bits;  conditional E-value: 9.7e-10
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56  
                  L+e+g a +  ++ +g+tpLh A  +++ d+v++Ll++ga+++ +d++G+t+l+ A
  EEA22776.1 1470 LIENG-AEIESENWRGETPLHCA-TGNRRDIVKVLLENGANIKSKDEQGQTPLQRA 1523
                  78999.66666666667****87.56***************************976 PP

  == domain 28  score: 27.2 bits;  conditional E-value: 1.5e-09
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltal 53  
                  Lle+g ad+n +d +  tpL +A  +g+  v+rlL+++gad++l+d++G+t++
  EEA22776.1 1535 LLEKG-ADPNSKDHKDKTPLWWATGNGHVAVMRLLIENGADPKLKDEQGRTLM 1586
                  89999.********************************************985 PP

>> HET  Heterokaryon incompatibility protein (HET)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.6   0.2   1.2e-08   2.6e-05       1      79 [.     158     232 ..     158     241 .. 0.91
   2 ?    5.0   0.2     0.013        29     121     144 ..     241     264 ..     234     266 .. 0.83

  Alignments for each domain:
  == domain 1  score: 24.6 bits;  conditional E-value: 1.2e-08
         HET   1 YeaLSYvWgdskekeeievngklleltenledalqvlrk.lgerylWiDaiCInQdddkekskqvqlmadIYsnAelviv 79 
                 + a+S+vW d + +  ++       + + l++  + + + l+ + +W D+iCI ++ ++ ++  +++m++ Y+ A+++++
  EEA22776.1 158 FMAISHVWSDGTGTGGLSQ----GGINQCLYNYFKGIAErLQCEGIWWDSICIPRE-KAARNIAINRMQSNYEVARVTLI 232
                 689********99999965....8899999999999877699**************.99******************997 PP

  == domain 2  score: 5.0 bits;  conditional E-value: 0.013
         HET 121 llekeeraieellespwfkRvWvl 144
                 ++ + e+a  +++ spwf+R+W+ 
  EEA22776.1 241 EWFDAETACFAIIMSPWFSRGWTA 264
                 566788899999**********96 PP

>> VWA_3_C  von Willebrand factor type A C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0      0.11   2.4e+02       1      16 [.     751     766 ..     751     767 .. 0.94
   2 ?   -0.0   0.0      0.37   8.2e+02       3      24 ..     818     839 ..     816     842 .. 0.80
   3 ?   -2.8   0.0       2.6   5.9e+03       3      15 ..     851     863 ..     851     865 .. 0.87
   4 ?   -1.4   0.0      0.98   2.2e+03       3      15 ..     948     960 ..     948     962 .. 0.93
   5 ?   -3.3   0.0       3.9   8.8e+03       3      15 ..     977     989 ..     977     992 .. 0.80
   6 ?    1.3   0.0      0.14   3.2e+02       2      17 ..    1009    1024 ..    1008    1025 .. 0.93
   7 !    8.0   0.0    0.0012       2.7       2      15 ..    1099    1112 ..    1098    1115 .. 0.89
   8 !    5.9   0.2    0.0051        12       1      16 [.    1164    1179 ..    1164    1199 .. 0.79
   9 ?    1.1   0.0      0.17   3.7e+02       3      17 ..    1199    1213 ..    1197    1213 .. 0.91
  10 ?   -0.3   0.0      0.43   9.7e+02       3      15 ..    1266    1278 ..    1265    1281 .. 0.90
  11 ?    2.7   0.0     0.052   1.2e+02       3      17 ..    1295    1309 ..    1294    1316 .. 0.86
  12 ?   -1.2   0.0      0.86   1.9e+03       3      15 ..    1358    1370 ..    1357    1372 .. 0.89
  13 ?   -1.4   0.0      0.98   2.2e+03       3      16 ..    1589    1602 ..    1588    1603 .. 0.93

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.11
                 HHHHHHT-HHHHHHHH CS
     VWA_3_C   1 eLAaeSGnedtaklLr 16 
                 +LAa+ G++  +++Lr
  EEA22776.1 751 HLAAARGHDAIVRMLR 766
                 69*************8 PP

  == domain 2  score: -0.0 bits;  conditional E-value: 0.37
                 HHHHT-HHHHH.HHHTTEEE.-T CS
     VWA_3_C   3 AaeSGnedtak.lLrkVVdvvDp 24 
                 Aae G e  a+ lL+k Vd+ D 
  EEA22776.1 818 AAEGGSEIVARqLLEKGVDI-DS 839
                 78888888775499******.75 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 2.6
                 HHHHT-HHHHHHH CS
     VWA_3_C   3 AaeSGnedtaklL 15 
                 Aa  G+e  ++lL
  EEA22776.1 851 AAQNGHEAVVRLL 863
                 7788*******99 PP

  == domain 4  score: -1.4 bits;  conditional E-value: 0.98
                 HHHHT-HHHHHHH CS
     VWA_3_C   3 AaeSGnedtaklL 15 
                 Aae G+e  ++lL
  EEA22776.1 948 AAENGHETVVQLL 960
                 89********999 PP

  == domain 5  score: -3.3 bits;  conditional E-value: 3.9
                 HHHHT-HHHHHHH CS
     VWA_3_C   3 AaeSGnedtaklL 15 
                 Aae G++  ++ L
  EEA22776.1 977 AAENGHDAVVRKL 989
                 89*****998655 PP

  == domain 6  score: 1.3 bits;  conditional E-value: 0.14
                  HHHHHT-HHHHHHHHT CS
     VWA_3_C    2 LAaeSGnedtaklLrk 17  
                  LAa  G+e  ++lL k
  EEA22776.1 1009 LAAKNGHEAVVRLLLK 1024
                  9*************87 PP

  == domain 7  score: 8.0 bits;  conditional E-value: 0.0012
                  HHHHHT-HHHHHHH CS
     VWA_3_C    2 LAaeSGnedtaklL 15  
                  +AaeSG+ed  +lL
  EEA22776.1 1099 MAAESGHEDVIRLL 1112
                  7***********98 PP

  == domain 8  score: 5.9 bits;  conditional E-value: 0.0051
                  HHHHHHT-HHHHHHHH CS
     VWA_3_C    1 eLAaeSGnedtaklLr 16  
                  ++Aae G+ed a+lL 
  EEA22776.1 1164 QMAAENGHEDVAQLLL 1179
                  68***********873 PP

  == domain 9  score: 1.1 bits;  conditional E-value: 0.17
                  HHHHT-HHHHHHHHT CS
     VWA_3_C    3 AaeSGnedtaklLrk 17  
                  Aae G+e+ ++lL k
  EEA22776.1 1199 AAENGHEGIVRLLIK 1213
                  99**********965 PP

  == domain 10  score: -0.3 bits;  conditional E-value: 0.43
                  HHHHT-HHHHHHH CS
     VWA_3_C    3 AaeSGnedtaklL 15  
                  A+e G+e  ++lL
  EEA22776.1 1266 ASENGHEAIVRLL 1278
                  89*********99 PP

  == domain 11  score: 2.7 bits;  conditional E-value: 0.052
                  HHHHT-HHHHHHHHT CS
     VWA_3_C    3 AaeSGnedtaklLrk 17  
                  Aae G+e+ ++lL k
  EEA22776.1 1295 AAENGHEGVVRLLLK 1309
                  99*********9976 PP

  == domain 12  score: -1.2 bits;  conditional E-value: 0.86
                  HHHHT-HHHHHHH CS
     VWA_3_C    3 AaeSGnedtaklL 15  
                  Aae Gne  +++L
  EEA22776.1 1358 AAEKGNEAVVRIL 1370
                  99*******9998 PP

  == domain 13  score: -1.4 bits;  conditional E-value: 0.98
                  HHHHT-HHHHHHHH CS
     VWA_3_C    3 AaeSGnedtaklLr 16  
                  Aae G++ +++lL+
  EEA22776.1 1589 AAENGHKTAVQLLK 1602
                  99**********97 PP

>> DUF5619  Domain of unknown function (DUF5619)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   0.1    0.0021       4.7      47      80 ..     869     901 ..     865     903 .. 0.86
   2 ?    2.1   0.0     0.084   1.9e+02      47      79 ..    1541    1572 ..    1537    1573 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0021
                 ES---SSSSSH...HHHHHHHTT--EEEEETTEE CS
     DUF5619  47 sPevecgeadkkpgwlvYgesrGakLeidindge 80 
                  P+++ ++ dk+p w+  g+ ++a +++ i++g+
  EEA22776.1 869 DPNSKDHK-DKTPLWWAAGNGHEAAIRLLIENGA 901
                 68877777.888******************9975 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.084
                  ES---SSSSSH...HHHHHHHTT--EEEEETTE CS
     DUF5619   47 sPevecgeadkkpgwlvYgesrGakLeidindg 79  
                   P+++ ++ dk+p w+  g+ + a +++ i++g
  EEA22776.1 1541 DPNSKDHK-DKTPLWWATGNGHVAVMRLLIENG 1572
                  68877777.888**************9999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1634 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       426  (0.0237604); expected 358.6 (0.02)
Passed bias filter:                      398  (0.0221987); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 1.06u 0.29s 00:00:01.35 Elapsed: 00:00:00.49
# Mc/sec: 10023.04
//
Query:       EEA22777.1  [L=451]
Description: peptidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-19   70.1   0.0    2.4e-19   69.2   0.0    1.5  1  M20_dimer      Peptidase dimerisation domain
    9.2e-15   54.9   0.0      3e-14   53.2   0.0    1.8  1  Peptidase_M20  Peptidase family M20/M25/M40
  ------ inclusion threshold ------
      0.011   15.4   0.0      0.029   14.1   0.0    1.6  1  Peptidase_M28  Peptidase family M28
      0.027   14.9   0.0       0.14   12.6   0.0    2.2  2  Secretin_N     Bacterial type II/III secretion system short d


Domain annotation for each model (and alignments):
>> M20_dimer  Peptidase dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.2   0.0   5.4e-23   2.4e-19       2     105 ..     241     349 ..     240     353 .. 0.92

  Alignments for each domain:
  == domain 1  score: 69.2 bits;  conditional E-value: 5.4e-23
                 EB-EEEEEEEEEE-B-EEGG-TTTTB-HHHHHHHHHHCSCTTEEC............TCCTCCCCCEECCE-CCCCEESSEEEEEEEEEHHHHHHHHHH CS
   M20_dimer   2 ghkGlaggkitvkgkagHsgapgagaNAieklarllaeledeegdia.......eerslprttlnvtgiegGsaknvipdeaeakidiRllpgedpeev 93 
                 ghkG++ +ki++kgka+Hsg+p  g++A+ +l  +l +l  + +           ++ l+++t+n++ i++G a+nv+p++aea+++iR l  +d+e+v
  EEA22777.1 241 GHKGSLFFKISAKGKAAHSGYPWLGQSAVSALLPALVKLDTLADI-PvedggipGSEKLGKSTINIGRIDAGIASNVVPASAEASVNIR-LAYHDVEKV 337
                 8**************************************998444.369****9***********************************.66799999* PP

                 HHHHHHHHTSCC CS
   M20_dimer  94 leeieeilekea 105
                 +e ++++++++ 
  EEA22777.1 338 KEIVTKAVDEAT 349
                 999999998875 PP

>> Peptidase_M20  Peptidase family M20/M25/M40
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.2   0.0   6.8e-18     3e-14       1     206 [.     127     443 ..     127     444 .. 0.79

  Alignments for each domain:
  == domain 1  score: 53.2 bits;  conditional E-value: 6.8e-18
                    EEEEES-BSSTTCGGGSSSTTSEE..ETTT............EEESTTTTTTHHHHHHHHHHHHHHHHHTTT-SSEEEEEEESTTSSTTTHHHHHH CS
                    xxxxxxxxxxxxxxxxxxxxxxxx..xxxx............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_M20   1 llgsHlDvVpeeetdgwttpfslt..eedG............klyGrGaddmkggvlaalealralkdegikpkgtivllfqpdEEggrgGakall 82 
                    ll sH+D+Vp         p+sl+    +G             + GrG++d k++v++ + a+ ++ + +  p+ ++ llf++ EE+ + G++++ 
     EEA22777.1 127 LLSSHMDTVP-PYI-----PYSLDlpSSNGsttdslnwrdniLIAGRGSVDAKASVASQILAVLEYLQLH--PEAPLGLLFVVGEEVDGIGMQYFS 214
                    699*******.333.....888888855566777888888889********************9999998..688***********988******* PP

                    HHHHTTTCESEEEEEEEESSSBTCHSTETEEEE............................................................... CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............................................................... RF
  Peptidase_M20  83 egleerekvdavfelhieepgileagklaigvv............................................................... 115
                    ++ + +  +  v  ++ +ep+ l        +v                                                               
     EEA22777.1 215 QSEL-NTSPPTVHTVIFGEPTELA-------LVsghkgslffkisakgkaahsgypwlgqsavsallpalvkldtladipvedggipgseklgkst 302
                    *655.2333333446788888888.......33345577888888888888888888888888888888888888888888888888888888999 PP

                    ...................................................EEEEEEE...EEESHEEEC.CHHHHHHHHHHHHH.HHTSCEEEEE CS
                    ...................................................xxxxxxx...xxxxxxxxx.xxxxxxxxxxxxxx.xxxxxxxxxx RF
  Peptidase_M20 116 ...................................................kvevell...eggapvtln.dsplvkalaeaaee.lfgekveliv 155
                                                                       +v++e+     g ap  ++ d + +k++   +   ++    ++  
     EEA22777.1 303 inigridagiasnvvpasaeasvnirlayhdvekvkeivtkavdeatngdeNVTIEWGnkgKGHAPIDFDtDVDGFKVMTVNYATdAWY--LKFHE 396
                    9999************************************9999999999779999887666677888888666666665443330222..22332 PP

                    ESSSBHTHHHHTTTEEEEEEESSG.GCTTSTTTEEEHHHHHHHHHHHHHHHH CS
                    xxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_M20 156 sgpggtdarffagiptvmifgpgs.glaHspnEyvdledlekgikvlarlle 206
                      +gg+  + +    t+ ++gpgs   aH+ +E + ++dle+++  +++l+e
     EEA22777.1 397 G-SGGSPEGRV---HTY-LYGPGSiFVAHGADEAITVRDLEDAVSGYKKLIE 443
                    2.355555555...244.7****88***********************9997 PP

>> Peptidase_M28  Peptidase family M28
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0   6.5e-06     0.029       6      86 ..     117     217 ..     113     231 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 6.5e-06
                    ESTTCESEEEEEEEE--B-TTT..........................TCCT---TTTT.HHHHHHHHHHHHHCHHGGCCSSEEEEEEEESSCSGS CS
  Peptidase_M28   6 legkatdevlllgAHyDsvgvg..........................rgpifvGAdDn.AsgvaalLelarvlaasgsrpkrgvrflffdaEEag 74 
                    +++++++ ++ll++H+D+v+                                  G  D  As ++ +L ++++l+    +p+  + +lf+ +EE  
     EEA22777.1 117 YPNSTPEPRVLLSSHMDTVPPYipysldlpssngsttdslnwrdniliA---GRGSVDAkASVASQILAVLEYLQL---HPEAPLGLLFVVGEEVD 206
                    44555466************889*********99999888885544443...4599996266666799******96...9**************** PP

                    SHHHHHHHHHHC CS
  Peptidase_M28  75 llGSkafakakp 86 
                     +G ++f + ++
     EEA22777.1 207 GIGMQYFSQ-SE 217
                    ******995.33 PP

>> Secretin_N  Bacterial type II/III secretion system short domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0      0.89     4e+03      36      53 ..     102     119 ..      74     120 .. 0.80
   2 ?   12.6   0.0   3.1e-05      0.14       4      74 ..     327     443 ..     324     445 .. 0.95

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.89
                 ...SSTT-TTSEEEEETT CS
  Secretin_N  36 sqsgallgkggrvvadpr 53 
                 +++ +++g+++++ a+p+
  EEA22777.1 102 PKGPKGQGERFNIYAYPN 119
                 566788999999999996 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 3.1e-05
                 EE-SSS-HHHHHHHHHHHCCTT...........................................................SSTT-TTSEEEEETTTTE CS
  Secretin_N   4 fpLkyasaadlasiLrellgggggesas..............................................sgassqsgallgkggrvvadprtNs 56 
                 ++L y +++++ +i+++++++  +++++                                              s+ +     l g+g  +va+ +  +
  EEA22777.1 327 IRLAYHDVEKVKEIVTKAVDEATNGDENvtiewgnkgkghapidfdtdvdgfkvmtvnyatdawylkfhegsggSPEGRVHTYLYGPGSIFVAHGADEA 425
                 89*****************999999999******************************************998888888888899************** PP

                 EEEEECHHHHHHHHHHHH CS
  Secretin_N  57 llvrgspervarirqlik 74 
                 + vr+ ++ v  +++li+
  EEA22777.1 426 ITVRDLEDAVSGYKKLIE 443
                 *****************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (451 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       360  (0.0200792); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.48
# Mc/sec: 2828.75
//
Query:       EEA22778.1  [L=934]
Description: sensor histidine kinase/response regulator, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.5e-20   73.8   0.0    3.2e-20   72.7   0.0    1.6  1  HATPase_c     Histidine kinase-, DNA gyrase B-, and HSP90-lik
    2.1e-16   60.1   0.6    0.00021   21.4   0.0    3.6  3  Response_reg  Response regulator receiver domain
    8.7e-06   25.7   0.1    2.2e-05   24.4   0.1    1.6  1  HisKA         His Kinase A (phospho-acceptor) domain
  ------ inclusion threshold ------
      0.062   13.1   0.0       0.14   12.0   0.0    1.5  1  HATPase_c_3   Histidine kinase-, DNA gyrase B-, and HSP90-lik
        2.3    8.7   4.3        2.4    8.6   0.3    3.0  3  NUDE_C        NUDE protein, C-terminal conserved region


Domain annotation for each model (and alignments):
>> HATPase_c  Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.7   0.0   8.9e-24   3.2e-20       2     111 ..     531     647 ..     530     648 .. 0.94

  Alignments for each domain:
  == domain 1  score: 72.7 bits;  conditional E-value: 8.9e-24
                 HHHHHHHHHHHHHHHHHHHHSTTTEEEEEEEEEE...TEEEEEEEESSSSSTTHHHTGTCSTTCH.HCSTCHTSTSSSHHHHHHHHHHHHTTTEEEE.. CS
   HATPase_c   2 dekrLrqiisnlvdNavkfatkageieveikase...ddlvisveDnGiGipkedlkklfekfsq.ddstkrggggtGlGlsivkklvelmgGeiwv.. 94 
                 de+ L ++is +  Navkf t++g+i+v  ++s+   ++++i ++D+G Gip+e  + lf++f + ddst+r+  g GlGl ++k l+++mgG++ +  
  EEA22778.1 531 DERDLAKLISCVFLNAVKF-TESGDIKVLTTSSNktpQYIRINIRDTGTGIPEEFFPSLFKPFAReDDSTTRTRDGLGLGLLVAKGLARKMGGDLLCvh 628
                 8999***************.*******98886335678********************************************************99999 PP

                 ..EEETTTEEEEEEEEESS CS
   HATPase_c  95 ..esepgrGttftftlple 111
                   +s p+rG++f +++pl+
  EEA22778.1 629 ssTSGPERGSEFEIRIPLN 647
                 888999**********985 PP

>> Response_reg  Response regulator receiver domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0   5.9e-08   0.00021       2      41 ..     743     782 ..     742     787 .. 0.95
   2 !   20.6   0.1     1e-07   0.00037      42      66 ..     824     848 ..     813     858 .. 0.86
   3 !   14.2   0.0   1.1e-05     0.038      71     109 ..     886     924 ..     882     927 .. 0.92

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 5.9e-08
                   EEESSSHHHHHHHHHHHHHTTEEEEEEESSHHHHHHHHHH CS
  Response_reg   2 livdDdplvrellrqlleeegyeevaeaedgkealellke 41 
                   l+++D++++r++l ++l++ gy++v ea dg+ea+++++e
    EEA22778.1 743 LVAEDNQINRKILVNMLRKLGYRDVYEAYDGREAVRIMQE 782
                   89**********************************9987 PP

  == domain 2  score: 20.6 bits;  conditional E-value: 1e-07
                   HHESEEEEESSCSSSEHHHHHHHHH CS
  Response_reg  42 ekvdlillDinmpgmdGlellkeir 66 
                   + +d++l+D+ mp+mdG+e++++i 
    EEA22778.1 824 KPIDVVLMDLWMPEMDGYEATSKIF 848
                   569*******************994 PP

  == domain 3  score: 14.2 bits;  conditional E-value: 1.1e-05
                   TSEEEEEESSTSHHHHHHHHHCTESEEEESSG-HHHHHH CS
  Response_reg  71 elpviiltahseeedavealkagaddflsKpfdpeeLlk 109
                   +++v++++a  ++e +++a ++g++++++Kp++ ++L  
    EEA22778.1 886 SPKVLAVSADVTDEALNRASQVGIQGYMTKPYKLADLER 924
                   579******************************999976 PP

>> HisKA  His Kinase A (phospho-acceptor) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4   0.1   6.1e-09   2.2e-05       8      52 ..     270     327 ..     268     335 .. 0.91

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 6.1e-09
                 HHHHHHHHHHHHHHHHHHHHHC...............T-HSSCHHHHHHHHHHHHHHH CS
       HisKA   8 gvaHELrtPLsailgnaeaLkre.............gklteelkeyletiesearrld 52 
                 +++HELrtP+ ++ g+++++                 +l ++lke++e ++++arr  
  EEA22778.1 270 SLSHELRTPMQGVVGMLDVMHANveeaiaasvapksFRLLQDLKENIELVQDSARRAV 327
                 58******************7778889********988899**************976 PP

>> HATPase_c_3  Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0     4e-05      0.14      28      71 ..     564     607 ..     545     636 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 4e-05
  HATPase_c_3  28 knrgktgeivieDdGkGmseeelknalr.latsskeakrkstslG 71 
                  k   +  +i i+D G+G++ee + + ++ +a+++ +++r+++ lG
   EEA22778.1 564 KT-PQYIRINIRDTGTGIPEEFFPSLFKpFAREDDSTTRTRDGLG 607
                  22.245899******************945666666555554443 PP

>> NUDE_C  NUDE protein, C-terminal conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.3   0.00066       2.4      53     119 ..     215     278 ..     210     284 .. 0.75
   2 ?   -1.3   0.0      0.76   2.7e+03      44      81 ..     309     349 ..     308     374 .. 0.64
   3 ?   -2.3   0.1       1.5   5.4e+03      66     128 ..     380     450 ..     368     472 .. 0.60

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.00066
      NUDE_C  53 iiqeklrkaeeklrrrkplslsspstpqsleiekrspavqasssPviatppekslsslatgsetatp 119
                 i q+ l ++ ++  +  + +ls ps+p s+ei+++ + ++a +sP++a+p++    sl+   e  tp
  EEA22778.1 215 ITQRVLDETGSQ-TQLSEPALSLPSKPLSQEIDAHPQPTSAPASPIFAHPLKPYAPSLS--HELRTP 278
                 666666554444.3334444577*************************99988877777..666666 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.76
      NUDE_C  44 lsDLkveleiiqeklrkaeek...lrrrkplslsspstpqs 81 
                 l+DLk + e +q+  r a e+     +  +l ++ p tpq+
  EEA22778.1 309 LQDLKENIELVQDSARRAVEAadnVVHAYDLNMEVPETPQK 349
                 689******99999887655533233344445577777754 PP

  == domain 3  score: -2.3 bits;  conditional E-value: 1.5
      NUDE_C  66 rrrkplsl.......sspstpqsleiekrspavqas..ssPviatppekslsslatgsetatppsPpasess 128
                 +rr+ +s+        + +++++ +++ rs   +a+  s +++ +p +  ++++  g+++a  ps +a+  +
  EEA22778.1 380 KRRRSISIdwaghgrPAKRSSRRSDLSPRSEVKNAVqeSDKIVYSPAKGRIEEVV-GNAVAQRPSLAARRMA 450
                 5666666654322211222234555555565555657666666666666655665.6666777777776665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (934 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       455  (0.0253779); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.73u 0.33s 00:00:01.06 Elapsed: 00:00:00.48
# Mc/sec: 5796.30
//
Query:       EEA22779.1  [L=347]
Description: hypothetical protein PMAA_093930 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.2e-09   37.1   0.2    6.3e-09   36.2   0.2    1.4  1  EHN       Epoxide hydrolase N terminus


Domain annotation for each model (and alignments):
>> EHN  Epoxide hydrolase N terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2   0.2   3.5e-13   6.3e-09      10     100 ..      66     170 ..      59     173 .. 0.60

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 3.5e-13
         EHN  10 qeelddlkkrlelt.........rlpeeeaeeee.eweeGvtkdelkelldyWkeeyd...........Wraeearln.sfpqfkteid......gldi 80 
                 ++ l++l+ rl +          ++p+e ++e++ ewe+G                 +           Wr++ea+ln s+pq++t+++      ++++
  EEA22779.1  66 NQTLQNLHPRLLTFrpppklsstSVPDELSHEKSrEWEHGR----------------SirrhqashttyWRKAEAELNdSLPQYMTSVSvewfeeDVEV 148
                 56666666666666222211111334444333334444443................222223333333*********9********943345446*** PP

         EHN  81 hFihlrsakpd..aiPllllhG 100
                 hF+    + ++   +Pll+lhG
  EEA22779.1 149 HFVYRARRVEKgrGVPLLFLHG 170
                 ***998644443379******9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (347 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       266  (0.0148363); expected 358.6 (0.02)
Passed bias filter:                      242  (0.0134977); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.21s 00:00:00.65 Elapsed: 00:00:00.38
# Mc/sec: 2751.07
//
Query:       EEA22780.1  [L=347]
Description: hypothetical protein PMAA_093930 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.2e-09   37.1   0.2    6.3e-09   36.2   0.2    1.4  1  EHN       Epoxide hydrolase N terminus


Domain annotation for each model (and alignments):
>> EHN  Epoxide hydrolase N terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.2   0.2   3.5e-13   6.3e-09      10     100 ..      66     170 ..      59     173 .. 0.60

  Alignments for each domain:
  == domain 1  score: 36.2 bits;  conditional E-value: 3.5e-13
         EHN  10 qeelddlkkrlelt.........rlpeeeaeeee.eweeGvtkdelkelldyWkeeyd...........Wraeearln.sfpqfkteid......gldi 80 
                 ++ l++l+ rl +          ++p+e ++e++ ewe+G                 +           Wr++ea+ln s+pq++t+++      ++++
  EEA22780.1  66 NQTLQNLHPRLLTFrpppklsstSVPDELSHEKSrEWEHGR----------------SirrhqashttyWRKAEAELNdSLPQYMTSVSvewfeeDVEV 148
                 56666666666666222211111334444333334444443................222223333333*********9********943345446*** PP

         EHN  81 hFihlrsakpd..aiPllllhG 100
                 hF+    + ++   +Pll+lhG
  EEA22780.1 149 HFVYRARRVEKgrGVPLLFLHG 170
                 ***998644443379******9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (347 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       266  (0.0148363); expected 358.6 (0.02)
Passed bias filter:                      242  (0.0134977); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.22s 00:00:00.67 Elapsed: 00:00:00.39
# Mc/sec: 2652.67
//
Query:       EEA22781.1  [L=206]
Description: proteasome component Pup3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.4e-41  141.3   0.0    2.8e-41  141.1   0.0    1.0  1  Proteasome  Proteasome subunit


Domain annotation for each model (and alignments):
>> Proteasome  Proteasome subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  141.1   0.0   1.6e-45   2.8e-41       3     190 .]       8     191 ..       7     191 .. 0.98

  Alignments for each domain:
  == domain 1  score: 141.1 bits;  conditional E-value: 1.6e-45
                 HS-EEEEEEETTEEEEEEEEEEEETTEEEESSSSTSEEEEETTEEEEEEESHHHHHHHHHHHHHHHHHHHHHHSSGTCHHHHHHHHHHHHHHHHHHCTT CS
  Proteasome   3 kGttvvGikgkdgvvlaadkratagskllskstveKifkiddhigvafaGlaaDartlvrraraeaqlyrlrygrpipverlvarvaaklqaytqrsgr 101
                 +G+++v++ gkd+v++a+d r+ +++ ++s++ + Kif   + ++++++Gla D+ t+ + +r+++++yrlr++r i+++     +a+++++ ++++++
  EEA22781.1   8 NGGACVAMVGKDCVAIACDLRLGMQALTVSNN-FPKIFNYAPSTYLGITGLATDVTTVSDLFRYKVNMYRLREERHISPQ----TLANLVSSSLYERRF 101
                 699********************999997777.9**********************************************....*************** PP

                 TTTSEEEEEEEEE.TTTEEEEEEEETTSEEEEESSEEEESTTHHHHHHHHHHHHSTTBSHHHHHHHHHHHHHHHHHHBTTSCSSEEEEEE CS
  Proteasome 102 rpfgvslliagvd.eeggpeLyqidpsGsyieekdavaiGsgseaaktalekeykedltleeavelavkalkealerdklsgknievavi 190
                 +p+ vs +iag++  +g+p+++ +d +G++   kd+++ G++s+   + +e ++++dl  ++++e++ +al +a++rd+lsg++++v++i
  EEA22781.1 102 GPYFVSPVIAGINhTTGKPFICGFDSIGCIDFAKDFIVSGTASDQLFGTCEGLWEPDLGPDDLFETISQALLNAVDRDALSGWGANVYII 191
                 *************7789***********************************************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (206 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       381  (0.0212505); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.46
# Mc/sec: 1342.64
//
Query:       EEA22782.1  [L=192]
Description: proteasome component Pup3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.9e-38  130.5   0.0    5.5e-38  130.4   0.0    1.0  1  Proteasome  Proteasome subunit


Domain annotation for each model (and alignments):
>> Proteasome  Proteasome subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  130.4   0.0   3.1e-42   5.5e-38      10     190 .]       1     177 [.       1     177 [. 0.98

  Alignments for each domain:
  == domain 1  score: 130.4 bits;  conditional E-value: 3.1e-42
                 EEETTEEEEEEEEEEEETTEEEESSSSTSEEEEETTEEEEEEESHHHHHHHHHHHHHHHHHHHHHHSSGTCHHHHHHHHHHHHHHHHHHCTTTTTSEEE CS
  Proteasome  10 ikgkdgvvlaadkratagskllskstveKifkiddhigvafaGlaaDartlvrraraeaqlyrlrygrpipverlvarvaaklqaytqrsgrrpfgvsl 108
                 + gkd+v++a+d r+ +++ ++s++ + Kif   + ++++++Gla D+ t+ + +r+++++yrlr++r i+++     +a+++++ +++++++p+ vs 
  EEA22782.1   1 MVGKDCVAIACDLRLGMQALTVSNN-FPKIFNYAPSTYLGITGLATDVTTVSDLFRYKVNMYRLREERHISPQ----TLANLVSSSLYERRFGPYFVSP 94 
                 579*************999997777.9**********************************************....********************** PP

                 EEEEEE.TTTEEEEEEEETTSEEEEESSEEEESTTHHHHHHHHHHHHSTTBSHHHHHHHHHHHHHHHHHHBTTSCSSEEEEEE CS
  Proteasome 109 liagvd.eeggpeLyqidpsGsyieekdavaiGsgseaaktalekeykedltleeavelavkalkealerdklsgknievavi 190
                 +iag++  +g+p+++ +d +G++   kd+++ G++s+   + +e ++++dl  ++++e++ +al +a++rd+lsg++++v++i
  EEA22782.1  95 VIAGINhTTGKPFICGFDSIGCIDFAKDFIVSGTASDQLFGTCEGLWEPDLGPDDLFETISQALLNAVDRDALSGWGANVYII 177
                 ******7789***********************************************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (192 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       312  (0.017402); expected 358.6 (0.02)
Passed bias filter:                      309  (0.0172346); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.23s 00:00:00.66 Elapsed: 00:00:00.40
# Mc/sec: 1432.65
//
Query:       EEA22783.1  [L=171]
Description: proteasome component Pup3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.3e-32  111.1   0.0    5.4e-32  110.8   0.0    1.0  1  Proteasome  Proteasome subunit


Domain annotation for each model (and alignments):
>> Proteasome  Proteasome subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.8   0.0     3e-36   5.4e-32       3     158 ..       8     159 ..       7     163 .. 0.97

  Alignments for each domain:
  == domain 1  score: 110.8 bits;  conditional E-value: 3e-36
                 HS-EEEEEEETTEEEEEEEEEEEETTEEEESSSSTSEEEEETTEEEEEEESHHHHHHHHHHHHHHHHHHHHHHSSGTCHHHHHHHHHHHHHHHHHHCTT CS
  Proteasome   3 kGttvvGikgkdgvvlaadkratagskllskstveKifkiddhigvafaGlaaDartlvrraraeaqlyrlrygrpipverlvarvaaklqaytqrsgr 101
                 +G+++v++ gkd+v++a+d r+ +++ ++s++ + Kif   + ++++++Gla D+ t+ + +r+++++yrlr++r i+++     +a+++++ ++++++
  EEA22783.1   8 NGGACVAMVGKDCVAIACDLRLGMQALTVSNN-FPKIFNYAPSTYLGITGLATDVTTVSDLFRYKVNMYRLREERHISPQ----TLANLVSSSLYERRF 101
                 699********************999997777.9**********************************************....*************** PP

                 TTTSEEEEEEEEE.TTTEEEEEEEETTSEEEEESSEEEESTTHHHHHHHHHHHHSTTB CS
  Proteasome 102 rpfgvslliagvd.eeggpeLyqidpsGsyieekdavaiGsgseaaktalekeykedl 158
                 +p+ vs +iag++  +g+p+++ +d +G++   kd+++ G++s+   + +e ++++dl
  EEA22783.1 102 GPYFVSPVIAGINhTTGKPFICGFDSIGCIDFAKDFIVSGTASDQLFGTCEGLWEPDL 159
                 *************7789**************************************997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (171 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       251  (0.0139997); expected 358.6 (0.02)
Passed bias filter:                      235  (0.0131073); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.29s 00:00:00.73 Elapsed: 00:00:00.45
# Mc/sec: 1131.41
//
Query:       EEA22784.1  [L=520]
Description: UBX domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-24   86.3   0.3    3.6e-24   84.7   0.1    2.0  2  TUG-UBL1  TUG ubiquitin-like domain
    0.00065   19.8   0.0     0.0029   17.8   0.0    2.1  2  UBX       UBX domain
  ------ inclusion threshold ------
       0.06   13.4   0.2       0.19   11.8   0.0    1.9  2  RBD       Raf-like Ras-binding domain
      0.066   14.2   0.1         11    7.0   0.0    3.1  3  SRP19     SRP19 protein


Domain annotation for each model (and alignments):
>> TUG-UBL1  TUG ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.7   0.1   8.1e-28   3.6e-24       1      65 []       8      71 ..       8      71 .. 0.97
   2 ?   -3.5   0.0       2.9   1.3e+04      22      38 ..     168     185 ..     168     192 .. 0.61

  Alignments for each domain:
  == domain 1  score: 84.7 bits;  conditional E-value: 8.1e-28
    TUG-UBL1  1 itynfrrfkvkvtpnttlndvLeeackkfklddsasytLkhnnkpldlslpfRlsnLpngakLeL 65
                i++++rr+++k++p+++l dvL+eac+k++l d ++y+Lkh++k+ldlsl fRls L++gakLeL
  EEA22784.1  8 IDSTARRATIKTNPSKPLADVLQEACRKLGL-DASQYGLKHQSKQLDLSLIFRLSSLSSGAKLEL 71
                7899***************************.788*****************************9 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 2.9
    TUG-UBL1  22 Leeackkfkldds.a.syt 38 
                 L+++++++++ +s +  + 
  EEA22784.1 168 LQKSLAQLGF-NSgNvLFR 185
                 6788889998.55243444 PP

>> UBX  UBX domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.6   0.0       3.1   1.4e+04      59      79 ..     166     184 ..     164     185 .. 0.76
   2 !   17.8   0.0   6.4e-07    0.0029       7      43 ..     348     384 ..     344     395 .. 0.85

  Alignments for each domain:
  == domain 1  score: -3.6 bits;  conditional E-value: 3.1
                 GCCC.CSBCCCCTTTSCEEEEE CS
         UBX  59 tksd.kktLsdlgllpnstlvl 79 
                 +  d +k+L  l ++ ++++++
  EEA22784.1 166 S--DlQKSLAQL-GFNSGNVLF 184
                 3..445999999.999999986 PP

  == domain 2  score: 17.8 bits;  conditional E-value: 6.4e-07
                 EEEEEEETTSTEEEEEEESSSBHHHHHHHHHHHCCCC CS
         UBX   7 trlqiRlpdGsrlvrrFkksdtlesvyeyVdsklfek 43 
                 + +++R+p  s+ v +Fk++dt +++y +V+ +l++k
  EEA22784.1 348 IDVKVRFPEQSQVVAKFKQTDTGSTLYTFVRGCLNTK 384
                 6799***************************999876 PP

>> RBD  Raf-like Ras-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   4.3e-05      0.19      10      46 ..      13      49 ..      10      65 .. 0.85
   2 ?   -3.3   0.0       2.2   9.8e+03       3      21 ..     351     369 ..     350     369 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 4.3e-05
         RBD 10 qrtvvevkpgetvrdaLekalkkRglnpsacaVylkg 46
                +r+++++ p +++ d+L+ a+ k gl+ s++ +   +
  EEA22784.1 13 RRATIKTNPSKPLADVLQEACRKLGLDASQYGLKHQS 49
                5899************************998776655 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 2.2
         RBD   3 rvhLPngqrtvvevkpget 21 
                 +v  P ++ +v++ k+++t
  EEA22784.1 351 KVRFPEQSQVVAKFKQTDT 369
                 7889999999999988765 PP

>> SRP19  SRP19 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.0    0.0025        11      17      50 ..      13      46 ..       8      67 .. 0.86
   2 ?    2.8   0.1      0.05   2.3e+02      11      44 ..     309     344 ..     304     373 .. 0.78
   3 ?   -1.4   0.0         1   4.6e+03      56      80 ..     425     451 ..     415     462 .. 0.62

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0025
                --S-CCCSBSS--HHHHHHHHHHCTSCEEEEEEE CS
       SRP19 17 RrvpkelavenPtaqeiaealkalglevvvepek 50
                Rr + + + ++P+a+ ++ea+++lgl++     k
  EEA22784.1 13 RRATIKTNPSKPLADVLQEACRKLGLDASQYGLK 46
                99999*********************98766555 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.05
                 S-CCCT--S-CCCSBSS--HHHHHHHH..HHCTSCE CS
       SRP19  11 ktrkeGRrvpkelavenPtaqeiaeal..kalglev 44 
                  ++++GR  + +++v+ P+ +eiae +  ++ +l +
  EEA22784.1 309 AKSHQGRLNQLSKNVRLPSDKEIAEKAaaEQERLAA 344
                 56789******************9865114444444 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 1
                 TTCCEEEEEC-............SS-C CS
       SRP19  56 wanpGrVrvklk..edgkevnekiknk 80 
                    +GrV v+++  ++++    +  ++
  EEA22784.1 425 QGLRGRVLVNFTwiDNNQASAMAAATR 451
                 445799999996533444333334444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (520 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       648  (0.0361426); expected 358.6 (0.02)
Passed bias filter:                      483  (0.0269396); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.47
# Mc/sec: 3325.26
//
Query:       EEA22785.1  [L=103]
Description: 60S ribosomal protein L36 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    3.5e-40  136.1   5.9      4e-40  136.0   5.9    1.0  1  Ribosomal_L36e   Ribosomal protein L36e
     0.0025   17.9   0.2     0.0028   17.7   0.2    1.1  1  PBS_linker_poly  Phycobilisome Linker polypeptide
  ------ inclusion threshold ------
      0.015   15.5   2.0      0.017   15.3   2.0    1.2  1  MRP-L28          Mitochondrial ribosomal protein L28


Domain annotation for each model (and alignments):
>> Ribosomal_L36e  Ribosomal protein L36e
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  136.0   5.9   6.7e-44     4e-40       1      96 []       5     100 ..       5     100 .. 0.98

  Alignments for each domain:
  == domain 1  score: 136.0 bits;  conditional E-value: 6.7e-44
  Ribosomal_L36e   1 rsglavglnkGhkvtknvsklrpsrrkgrltkrtkfvrdiirevaGfapyerrvmellkvskdKralKfaKkrlgthirakrKreelsnvlaamr 95 
                     rsgl++glnkGhk+t  ++k+r sr+kgrl++rt+fvr+i++evaG+apyerrv+ell++s+dKra+K+aKkrlgt+ rak+K++e+++v+a+ r
      EEA22785.1   5 RSGLILGLNKGHKTTPIETKARISRSKGRLSRRTAFVREIVKEVAGLAPYERRVVELLRNSQDKRARKLAKKRLGTIGRAKAKVDEMQKVIAEAR 99 
                     6899*****************************************************************************************99 PP

  Ribosomal_L36e  96 k 96 
                     +
      EEA22785.1 100 R 100
                     6 PP

>> PBS_linker_poly  Phycobilisome Linker polypeptide
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.2   4.6e-07    0.0028      26      99 ..      24     102 ..      15     103 .] 0.81

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 4.6e-07
                      CCSTHHHHHHHHTTSS-HHHHHHHHHCSHHHHHHHTT...TS-HHHHHHHHHHHH..TSS--SSHHHHHHHHHHHHHCH CS
  PBS_linker_poly  26 serlselesklkngeisvrefvralakSelYrkrfye...klsnyrvielafkhl..LGRapesqaEiskyskilaekG 99 
                      + r s+   +l++++  vre v+++a    Y++r++e   + +  r+ +la k+l  +GRa ++ +E++k+++  ++ G
       EEA22785.1  24 KARISRSKGRLSRRTAFVREIVKEVAGLAPYERRVVEllrNSQDKRARKLAKKRLgtIGRAKAKVDEMQKVIAEARRAG 102
                      56788888999***********************988221444568999999998889***********9987766655 PP

>> MRP-L28  Mitochondrial ribosomal protein L28
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.3   2.0   2.8e-06     0.017       7      67 ..      13      75 ..      10      99 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 2.8e-06
                XXXXXXXX....XXXXXXXXXXXX...XXXXXXXXXXXXXXXXSXSXXTTSSTTX..XSXXXXX CS
     MRP-L28  7 kkkkkvdpqvvkrreerakkrlek...qirkleksakelkPveelivplksvdsakrrqrklle 67
                +k +k++p  +k r +r k rl++    +r + k+  +l P e+++v+l   +s+++r+rkl +
  EEA22785.1 13 NKGHKTTPIETKARISRSKGRLSRrtaFVREIVKEVAGLAPYERRVVELL-RNSQDKRARKLAK 75
                67788888778877777776666522279******************976.5677799999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (103 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       833  (0.046461); expected 358.6 (0.02)
Passed bias filter:                      494  (0.0275531); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.40u 0.29s 00:00:00.69 Elapsed: 00:00:00.44
# Mc/sec: 699.94
//
Query:       EEA22786.1  [L=946]
Description: cytoskeleton organisation protein (Dec1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
   1.5e-102  343.4   6.1   1.5e-102  343.4   6.1    1.8  2  NatB_MDM20  N-acetyltransferase B complex (NatB) non catalyti
  ------ inclusion threshold ------
      0.037   14.5   0.2       0.53   10.8   0.0    3.0  2  TPR_19      Tetratricopeptide repeat
        1.3    9.2   3.9         16    5.7   0.1    3.7  4  DUF1296     Protein of unknown function (DUF1296)


Domain annotation for each model (and alignments):
>> NatB_MDM20  N-acetyltransferase B complex (NatB) non catalytic subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.1      0.47   2.8e+03      14      38 ..      19      42 ..       8      62 .. 0.66
   2 !  343.4   6.1  2.5e-106  1.5e-102       1     382 []     295     665 ..     295     665 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 0.47
  NatB_MDM20 14 lkekkesleevqkfieelikkeeak 38
                 ++  ++++++ ++i + ikk e++
  EEA22786.1 19 AID-AQNFKQALQLIDKRIKKGENT 42
                333.447777777777777776655 PP

  == domain 2  score: 343.4 bits;  conditional E-value: 2.5e-106
  NatB_MDM20   1 WkvwklyldsafklkekkesleevqkfieelikkeeakspksRnpyLArLelikrlrkrskkaeeektslsglvelileYfekfgsKlccfeDLkkYle 99 
                 W vw+l+l+s++k+++ k++ e++ +f++++ ++      ksRn++LA+Le++   r +s      + ++sgl+++ +++++ +++K++cf+DL+kY +
  EEA22786.1 295 WGVWSLLLTSTKKIDD-KKTSEDTVSFVQKFAQRF----SKSRNAHLALLEVSI-WRLESG-----ELEQSGLLAAYQNFYDFNSTKMYCFDDLRKYAS 382
                 99************99.88************8776....789************.333333.....33457799************************* PP

  NatB_MDM20 100 eLskeerkeflekvsslsksesesee.ekkekklrrlinalklercl..geheklseeekeelvtellaiYraslrlgaelletesqpsddlallaaha 195
                 +L+++++ +++e+      ++++s++  +++ + ++lina+kl +c+   ++ +ls++ +e+lv+++l++Yra+++ +a+ +++e+qp+ddl lla+++
  EEA22786.1 383 YLDQAQVLKLVEYAL----EKADSQKdVSTTAQQITLINAYKLDYCFkvFSNPELSKKRAEDLVSRCLKMYRAMKKEEASEKTIENQPRDDLGLLAVMS 477
                 **9999999999999....6667777699999***************999************************************************* PP

  NatB_MDM20 196 lldlseks....vdstlliqaillLeflltksphNfqlkLlLvrlYlllGagslalklyskLdiKqiQlDtlghllftrlstlgpfs........ka.. 280
                 l++l+e+s    v+s+ l++++++Le+l+++sphN+q++LlLvr+YlllGags a+k++skL++KqiQ++t++h+l+trl+t++p          k+  
  EEA22786.1 478 LISLNENSdqekVPSSELVRSAAILEHLCENSPHNYQILLLLVRVYLLLGAGSIAMKTFSKLSVKQIQNETVAHNLYTRLATIHPLGappieaefKDfi 576
                 *******9***999************************************************************************9899988774478 PP

  NatB_MDM20 281 .lslleqalrfYesaeketpesiakayekgsYskieefiefqerLknSlqramvaleerrlqrllgg....qyddlaekleaelkedeaepaedridws 374
                  + +l +a  fY++a+++t++ ++++++ gsY ++e++ie+qe L+nS++r+m+ale+rr++rl g+    +                   ++ ++d+s
  EEA22786.1 577 pEVALGHAIGFYDHADRTTTRQRTTGLNLGSYANVEGTIELQESLRNSICRRMWALEARRIDRLQGKdrfsR------------------FDDIISDQS 657
                 89****************************************************************432222..................333456899 PP

  NatB_MDM20 375 klsDnrdf 382
                 +l+D+r+f
  EEA22786.1 658 ELVDKRTF 665
                 99999987 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.1      0.35   2.1e+03      36      48 ..      20      32 ..      12      44 .. 0.61
   2 ?   10.8   0.0   8.9e-05      0.53      11      52 ..     499     540 ..     494     557 .. 0.80

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.35
      TPR_19 36 lalgqldeAealL 48
                + + ++++A +l+
  EEA22786.1 20 IDAQNFKQALQLI 32
                3334444444444 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 8.9e-05
      TPR_19  11 lalleqalqedpknaearllLAeallalgqldeAealLdalp 52 
                 +a+le + + +p+n  ++llL++++l lg    A+++ ++l 
  EEA22786.1 499 AAILEHLCENSPHNYQILLLLVRVYLLLGAGSIAMKTFSKLS 540
                 5788888888*******************9998888888775 PP

>> DUF1296  Protein of unknown function (DUF1296)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0     0.062   3.7e+02      18      38 ..      60      80 ..      57      86 .. 0.89
   2 ?   -2.5   0.0      0.97   5.8e+03      12      32 ..     217     237 ..     209     247 .. 0.73
   3 ?   -0.4   0.1      0.23   1.3e+03      34      44 ..     280     290 ..     276     292 .. 0.87
   4 ?    5.7   0.1    0.0027        16       5      21 ..     854     870 ..     851     874 .. 0.85

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.062
     DUF1296 18 khsdeeIyamLkecnmDpnea 38
                 hs++ I a+L  c+ Dp  +
  EEA22786.1 60 THSQQGITATLDICKLDPPTT 80
                499**************9765 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.97
     DUF1296  12 ikEivgkhsdeeIyamLkecn 32 
                 ik    +  deeI ++L   n
  EEA22786.1 217 IKIFQAQGRDEEILKILDSHN 237
                 5555556789***99997665 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 0.23
     DUF1296  34 DpneavqkLLs 44 
                 D +ea++kLL+
  EEA22786.1 280 DEDEAAKKLLQ 290
                 89*******96 PP

  == domain 4  score: 5.7 bits;  conditional E-value: 0.0027
     DUF1296   5 vrkviqsikEivgkhsd 21 
                 +++v+qs+kE++ k ++
  EEA22786.1 854 SKEVVQSLKEVATKLQE 870
                 79**********98766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (946 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       899  (0.0501422); expected 358.6 (0.02)
Passed bias filter:                      505  (0.0281667); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.73u 0.29s 00:00:01.02 Elapsed: 00:00:00.45
# Mc/sec: 6378.98
//
Query:       EEA22787.1  [L=478]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (478 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       732  (0.0408277); expected 358.6 (0.02)
Passed bias filter:                      500  (0.0278878); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.57u 0.26s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 3224.63
//
Query:       EEA22788.1  [L=510]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.4e-09   35.5   4.6    6.4e-09   35.5   4.6    2.1  2  zf-C3HC4       Zinc finger, C3HC4 type (RING finger)
    4.7e-08   33.2   7.1    4.7e-08   33.2   7.1    2.7  2  zf-RING_2      Ring finger domain
    4.2e-07   29.7   6.2    4.2e-07   29.7   6.2    2.2  2  zf-C3HC4_2     Zinc finger, C3HC4 type (RING finger)
    9.3e-07   28.6  12.2    1.2e-06   28.3   4.1    2.3  2  zf-C3HC4_3     Zinc finger, C3HC4 type (RING finger)
    1.3e-06   28.4   7.7    1.3e-06   28.4   7.7    2.4  2  zf-C3HC4_4     zinc finger of C3HC4-type, RING
    1.4e-06   28.2   7.0    3.9e-06   26.8   7.0    1.8  1  zf-RING_UBOX   RING-type zinc-finger
    4.1e-05   23.5   6.3    4.1e-05   23.5   6.3    2.2  2  zf-RING_5      zinc-RING finger domain
    0.00078   19.3   3.1    0.00078   19.3   3.1    2.1  2  zf-RING_6      zf-RING of BARD1-type protein
     0.0027   17.5   4.9     0.0027   17.5   4.9    2.3  2  Prok-RING_4    Prokaryotic RING finger family 4
     0.0053   16.8   1.6     0.0053   16.8   1.6    2.3  2  zf-ANAPC11     Anaphase-promoting complex subunit 11 RING-H2 
     0.0069   16.4  13.6      0.045   13.8   1.3    2.9  2  DZR            Double zinc ribbon
  ------ inclusion threshold ------
       0.09   12.7   0.4       0.16   11.9   0.4    1.3  1  Baculo_IE-1    Baculovirus immediate-early protein (IE-0)
       0.23   10.9   6.0       0.38   10.2   1.6    2.8  2  zf-ribbon_3    zinc-ribbon domain
       0.25   10.9   6.1        2.9    7.5   0.3    3.5  3  TF_Zn_Ribbon   TFIIB zinc-binding
       0.35   10.7  10.2        0.1   12.4   2.1    2.9  3  zf-RING_4      RING/Ubox like zinc-binding domain


Domain annotation for each model (and alignments):
>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.5   4.6   5.3e-12   6.4e-09       1      41 []      60     100 ..      60     100 .. 0.98
   2 ?   -1.7   0.9       2.3   2.8e+03       1      15 [.     187     200 ..     182     204 .. 0.56

  Alignments for each domain:
  == domain 1  score: 35.5 bits;  conditional E-value: 5.3e-12
                 -TTT-S--SS-E.E-TTS--B-CHHHHHHHHC.TSSB--TTT CS
    zf-C3HC4   1 CpiCleeakepnelleCkHsfCskCirkilks.rkkvkCPlC 41 
                 C iC   + ep  +l C+H+fC+ C++++ +s r++++CP C
  EEA22788.1  60 CGICVRPLYEPY-TLGCGHTFCYGCLTSWFSSgRSHKTCPDC 100
                 99**********.*******************999999**** PP

  == domain 2  score: -1.7 bits;  conditional E-value: 2.3
                 -TTT-S--SS-E.E- CS
    zf-C3HC4   1 CpiCleeakepnell 15 
                 Cp C  e++e    +
  EEA22788.1 187 CPNCAWELEEDA-CM 200
                 444544444444.44 PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.2   7.1   3.9e-11   4.7e-08       2      44 .]      59     101 ..      58     101 .. 0.83
   2 ?    1.3   0.9      0.37   4.4e+02       2      23 ..     186     204 ..     185     210 .. 0.63

  Alignments for each domain:
  == domain 1  score: 33.2 bits;  conditional E-value: 3.9e-11
   zf-RING_2   2 eCpICleelssadsvlllpCgHvfhreClerwlrssst...CPlCr 44 
                 +C+IC  +l +   + +l CgH+f++ Cl+ w+ s ++   CP Cr
  EEA22788.1  59 QCGICVRPLYE---PYTLGCGHTFCYGCLTSWFSSGRShktCPDCR 101
                 8*****99954...45556*************877666777****9 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.37
   zf-RING_2   2 eCpICleelssadsvlllpCgH 23 
                  Cp C  el+++ ++    Cg+
  EEA22788.1 186 RCPNCAWELEEDACMN---CGY 204
                 5888966776533333...874 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.7   6.2   3.5e-10   4.2e-07       1      40 []      59     100 ..      59     100 .. 0.88
   2 ?   -1.5   0.7       1.9   2.3e+03      36      40 .]     186     190 ..     181     205 .. 0.64

  Alignments for each domain:
  == domain 1  score: 29.7 bits;  conditional E-value: 3.5e-10
  zf-C3HC4_2   1 kCpiCldmlkdpsvvtpCgHvfCqkCilrsLe...ekneCPlC 40 
                 +C iC+  l++p ++  CgH+fC+ C+  + +   +++ CP C
  EEA22788.1  59 QCGICVRPLYEP-YTLGCGHTFCYGCLTSWFSsgrSHKTCPDC 100
                 7***********.****************9862225679**99 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1.9
  zf-C3HC4_2  36 eCPlC 40 
                 +CP C
  EEA22788.1 186 RCPNC 190
                 45555 PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.3   4.1   9.6e-10   1.2e-06       4      48 ..      59     105 ..      57     106 .. 0.96
   2 ?    4.9   1.0     0.021        25      26      48 ..     187     207 ..     184     208 .. 0.85

  Alignments for each domain:
  == domain 1  score: 28.3 bits;  conditional E-value: 9.6e-10
                 B-TTTSSSBS-EEETTEEEEEE-HHHHHHHHH...TT-B-TTT--B-- CS
  zf-C3HC4_3   4 eCviClerprnvvllpCgHlvlCeeCaekllk...rkkkCpiCrrpie 48 
                 +C iC +   +   l CgH+ +C+ C++++ +   ++k+Cp Cr++++
  EEA22788.1  59 QCGICVRPLYEPYTLGCGHT-FCYGCLTSWFSsgrSHKTCPDCRAQVK 105
                 6*******************.**********99*9*********9985 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.021
                 -HHHHHHHHHTT-B-TTT--B-- CS
  zf-C3HC4_3  26 CeeCaekllkrkkkCpiCrrpie 48 
                 C +Ca +l  +++ C+ C  ++e
  EEA22788.1 187 CPNCAWEL--EEDACMNCGYHVE 207
                 99******..89******87776 PP

>> zf-C3HC4_4  zinc finger of C3HC4-type, RING
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.4   7.7   1.1e-09   1.3e-06       1      42 []      60     100 ..      60     100 .. 0.96
   2 ?    2.9   1.0      0.11   1.3e+02       1      19 [.     187     205 ..     187     211 .. 0.94

  Alignments for each domain:
  == domain 1  score: 28.4 bits;  conditional E-value: 1.1e-09
  zf-C3HC4_4   1 CPiCldYLekPvsleCGhsfClsCisslqkepdgeqllCplC 42 
                 C iC+  L +P +l CGh+fC  C++s+  +  +   +Cp C
  EEA22788.1  60 CGICVRPLYEPYTLGCGHTFCYGCLTSWFSSGRSH-KTCPDC 100
                 99**************************9999886.89**99 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.11
  zf-C3HC4_4   1 CPiCldYLekPvsleCGhs 19 
                 CP C   Le+ + ++CG+ 
  EEA22788.1 187 CPNCAWELEEDACMNCGYH 205
                 9****************96 PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   7.0   3.3e-09   3.9e-06       1      39 []      60      98 ..      60      98 .. 0.86

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 3.3e-09
  zf-RING_UBOX  1 CpIClelftdPlv.lpCGHtFCreCl..welskslegafkCP 39
                  C IC  ++ +P   l+CGHtFC  Cl  w   +s++ + +CP
    EEA22788.1 60 CGICVRPLYEP-YtLGCGHTFCYGCLtsW--FSSGRSHKTCP 98
                  9**********.535***********665..78888888898 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   6.3   3.4e-08   4.1e-05       2      43 ..      60     101 ..      59     102 .. 0.96
   2 ?   -1.2   1.4       1.8   2.1e+03       2      42 ..     187     202 ..     185     206 .. 0.52

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 3.4e-08
   zf-RING_5   2 CnkCfeklskeekfyltsCgHifCekClkkll...ekeavCpiCr 43 
                 C +C ++l    ++y++ CgH+fC  Cl+  +    + ++Cp Cr
  EEA22788.1  60 CGICVRPL---YEPYTLGCGHTFCYGCLTSWFssgRSHKTCPDCR 101
                 ********...99*******************9*99********9 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 1.8
   zf-RING_5   2 CnkCfeklskeekfyltsCgHifCekClkkllekeavCpiC 42 
                 C+                       +C+ +l   e+ C  C
  EEA22788.1 187 CP-----------------------NCAWELE--EDACMNC 202
                 44.......................4444444..4455444 PP

>> zf-RING_6  zf-RING of BARD1-type protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.3   3.1   6.6e-07   0.00078       5      53 ..      55     107 ..      51     111 .. 0.81
   2 ?    0.5   0.2      0.46   5.5e+02       8      28 ..     185     205 ..     181     214 .. 0.80

  Alignments for each domain:
  == domain 1  score: 19.3 bits;  conditional E-value: 6.6e-07
   zf-RING_6   5 ekllrcsrctdilrepvclggcehifcsncisdcfgsg.....cpvcytpawiq 53 
                   l++c  c   l ep  l gc h fc  c++  f sg     cp c +   iq
  EEA22788.1  55 RALIQCGICVRPLYEPYTL-GCGHTFCYGCLTSWFSSGrshktCPDCRAQVKIQ 107
                 5699**************9.5****************95555556555554444 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.46
   zf-RING_6   8 lrcsrctdilrepvclggceh 28 
                  rc  c+  l e  c+    h
  EEA22788.1 185 ARCPNCAWELEEDACMNCGYH 205
                 689999999999999876666 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.5   4.9   2.3e-06    0.0027       1      41 [.      60     105 ..      60     109 .. 0.86
   2 ?   -0.3   0.7      0.84     1e+03      31      42 ..     185     196 ..     165     206 .. 0.78

  Alignments for each domain:
  == domain 1  score: 17.5 bits;  conditional E-value: 2.3e-06
  Prok-RING_4   1 CvlCgeqekkailepCgHlvCkeCfdskdls.....sCPlCqrris 41 
                  C +C +   ++    CgH +C  C+ s+ +s     +CP C+ +++
   EEA22788.1  60 CGICVRPLYEPYTLGCGHTFCYGCLTSWFSSgrshkTCPDCRAQVK 105
                  888888888999999*************66667777******9875 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.84
  Prok-RING_4  31 ssCPlCqrrisk 42 
                  ++CP C  ++++
   EEA22788.1 185 ARCPNCAWELEE 196
                  489999877765 PP

>> zf-ANAPC11  Anaphase-promoting complex subunit 11 RING-H2 finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   1.6   4.4e-06    0.0053      52      84 ..      75     107 ..      58     108 .. 0.88
   2 ?   -2.9   0.3       6.2   7.5e+03      35      40 ..     187     192 ..     182     209 .. 0.59

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 4.4e-06
                 TS-EEEHHHHHHHHHHHSTSSB-TTTSSB--BE CS
  zf-ANAPC11  52 ckhnfhlhcilkwletetskglcpmcrqtfklk 84 
                 c h+f   c++ w+++  s++ cp cr ++k++
  EEA22788.1  75 CGHTFCYGCLTSWFSSGRSHKTCPDCRAQVKIQ 107
                 ***************************998875 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 6.2
                 -TTCST CS
  zf-ANAPC11  35 cpsckf 40 
                 cp+c +
  EEA22788.1 187 CPNCAW 192
                 555543 PP

>> DZR  Double zinc ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.0   5.1    0.0099        12      12      39 ..      77     105 ..      52     112 .. 0.67
   2 !   13.8   1.3   3.8e-05     0.045      10      39 ..     182     207 ..     166     210 .. 0.86

  Alignments for each domain:
  == domain 1  score: 6.0 bits;  conditional E-value: 0.0099
         DZR  12 arfCseCgtklkavaa.edrCpsCgekvd 39 
                   fC+ C t+  +  + +++Cp C ++v+
  EEA22788.1  77 HTFCYGCLTSWFSSGRsHKTCPDCRAQVK 105
                 45777777774333335888888888775 PP

  == domain 2  score: 13.8 bits;  conditional E-value: 3.8e-05
         DZR  10 pdarfCseCgtklkavaaedrCpsCgekvd 39 
                 ++   C++C  +l+    ed+C++Cg+ v+
  EEA22788.1 182 DGVARCPNCAWELE----EDACMNCGYHVE 207
                 55668********9....9*******9986 PP

>> Baculo_IE-1  Baculovirus immediate-early protein (IE-0)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.4   0.00013      0.16      78     132 ..      55     105 ..      18     111 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00013
  Baculo_IE-1  78 kklyqcnicedtsaeerflkPneccGykicnlcyanlwkfstvyPvcPvcktsfk 132
                  + l qc+ic     e   l     cG+  c+ c +  +   + + +cP c++  k
   EEA22788.1  55 RALIQCGICVRPLYEPYTL----GCGHTFCYGCLTSWFSSGRSHKTCPDCRAQVK 105
                  3688999999999888766....6************999999********99877 PP

>> zf-ribbon_3  zinc-ribbon domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.2      0.17     2e+02       2      10 ..      94     102 ..      93     107 .. 0.67
   2 ?   10.2   1.6   0.00032      0.38       4      24 ..     186     204 ..     184     205 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.17
  zf-ribbon_3   2 tvrCPnCGa 10 
                  +++CP C a
   EEA22788.1  94 HKTCPDCRA 102
                  678888855 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 0.00032
  zf-ribbon_3   4 rCPnCGa.plssddnvCpyCGt 24 
                  rCPnC + + ++d+  C +CG+
   EEA22788.1 186 RCPNCAWeL-EEDA--CMNCGY 204
                  9******77.7775..999997 PP

>> TF_Zn_Ribbon  TFIIB zinc-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.1       1.2   1.4e+03       2       6 ..      96     100 ..      92     104 .. 0.76
   2 ?    7.5   0.3    0.0024       2.9      12      35 ..     177     200 ..     171     201 .. 0.89
   3 ?    6.3   0.1    0.0057       6.8      22      39 ..     199     216 ..     198     219 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 1.2
                   EETTT CS
  TF_Zn_Ribbon   2 kCPnC 6  
                   +CP+C
    EEA22788.1  96 TCPDC 100
                   47777 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0024
                   HEETSTTCEEESSSSBEEEECCCC CS
  TF_Zn_Ribbon  12 veDpergelvCtdCGlVlednsid 35 
                   ++D+e g  +C++C   le++ ++
    EEA22788.1 177 IYDAEDGVARCPNCAWELEEDACM 200
                   699************999999876 PP

  == domain 3  score: 6.3 bits;  conditional E-value: 0.0057
                   ESSSSBEEEECCCCCCCH CS
  TF_Zn_Ribbon  22 CtdCGlVlednsidegpe 39 
                   C +CG+ +ed  id   +
    EEA22788.1 199 CMNCGYHVEDGTIDDSDD 216
                   *************98765 PP

>> zf-RING_4  RING/Ubox like zinc-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   2.1   8.4e-05       0.1      20      46 ..      75     103 ..      72     105 .. 0.89
   2 ?    3.0   0.1     0.073        87      35      43 ..     182     190 ..     174     195 .. 0.82
   3 ?   -3.5   0.2       8.2   9.8e+03      18      23 ..     199     205 ..     197     206 .. 0.63

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 8.4e-05
   zf-RING_4  20 CgyqiClfCyhrile..eeegrCPaCree 46 
                 Cg+ +C  C++   +  ++++ CP Cr +
  EEA22788.1  75 CGHTFCYGCLTSWFSsgRSHKTCPDCRAQ 103
                 ************9996567********75 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.073
   zf-RING_4  35 eeegrCPaC 43 
                 +  +rCP+C
  EEA22788.1 182 DGVARCPNC 190
                 5679***** PP

  == domain 3  score: -3.5 bits;  conditional E-value: 8.2
   zf-RING_4  18 C.eCgyq 23 
                 C +Cgy+
  EEA22788.1 199 CmNCGYH 205
                 5467776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (510 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1344  (0.0749624); expected 358.6 (0.02)
Passed bias filter:                      659  (0.0367561); expected 358.6 (0.02)
Passed Vit filter:                        95  (0.00529868); expected 17.9 (0.001)
Passed Fwd filter:                        43  (0.00239835); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.82u 0.34s 00:00:01.15 Elapsed: 00:00:00.51
# Mc/sec: 3027.92
//
Query:       EEA22789.1  [L=631]
Description: small nucleolar ribonucleoprotein complex subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      4e-21   74.9   7.1    5.8e-06   27.0   0.0    5.8  6  WD40         WD domain, G-beta repeat
    0.00019   21.6   0.0     0.0062   16.8   0.0    2.5  2  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
  ------ inclusion threshold ------
      0.026   13.8   0.0      0.053   12.9   0.0    1.5  1  WD40_like    WD40-like domain
      0.059   13.0   0.4      0.091   12.4   0.4    1.2  1  DUF885       Bacterial protein of unknown function (DUF885)


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.0   0.0       3.7   1.6e+04      20      37 ..     164     179 ..     157     180 .. 0.65
   2 !   27.0   0.0   1.3e-09   5.8e-06       6      38 .]     224     257 ..     220     257 .. 0.91
   3 !   17.1   0.2   1.7e-06    0.0074       3      37 ..     263     304 ..     261     305 .. 0.91
   4 !   11.9   0.0   7.3e-05      0.33       6      38 .]     316     349 ..     312     349 .. 0.86
   5 !    7.2   0.0    0.0022       9.8      12      38 .]     368     397 ..     353     397 .. 0.74
   6 !   10.6   0.2   0.00019      0.85      13      37 ..     445     469 ..     435     470 .. 0.92

  Alignments for each domain:
  == domain 1  score: -3.0 bits;  conditional E-value: 3.7
                 TTSSEEEEEETTSEEEEE CS
        WD40  20 pdgawlasGsdDgtvriW 37 
                 p  a+  + s+D+t+  W
  EEA22789.1 164 PPFAY--TVSKDRTLIKW 179
                 44444..67899998766 PP

  == domain 2  score: 27.0 bits;  conditional E-value: 1.3e-09
                 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +  GH + +  la+sp+g++la+G++D+++ iWd
  EEA22789.1 224 EPQGHtGTILTLAVSPSGRYLATGGEDKKLIIWD 257
                 568**766*************************9 PP

  == domain 3  score: 17.1 bits;  conditional E-value: 1.7e-06
                 EEEEEESS.SSEEEEE......EETTSSEEEEEETTSEEEEE CS
        WD40   3 clrtltGH.ssvtsla......fspdgawlasGsdDgtvriW 37 
                 +++t+t H +s++sl+       +++g  l+sGs D+t++ W
  EEA22789.1 263 PMKTFTQHrDSISSLSftrhisSHSSGEQLFSGSFDRTIKTW 304
                 789*****999**999999999999999999*********99 PP

  == domain 4  score: 11.9 bits;  conditional E-value: 7.3e-05
                 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 tl GH ++v+s+a     + ++ G +D+t r+W+
  EEA22789.1 316 TLFGHqDHVSSVASMMTDQCVSVGARDRTARLWK 349
                 6669*888****98888888999*9********6 PP

  == domain 5  score: 7.2 bits;  conditional E-value: 0.0022
                 S....EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  12 s....vtslafspdgawlasGsdDgtvriWd 38 
                      + ++a+ p  +++ +Gsd g++ +W+
  EEA22789.1 368 YqnnvIDCVAVVPPTHFV-TGSDSGSLSLWS 397
                 055556899999999997.7**********5 PP

  == domain 6  score: 10.6 bits;  conditional E-value: 0.00019
                 EEEEEEETTSSEEEEEETTSEEEEE CS
        WD40  13 vtslafspdgawlasGsdDgtvriW 37 
                 +t+la+ p  + ++sGs+Dg +r W
  EEA22789.1 445 ITALATVPGTDIVLSGSWDGWIRAW 469
                 99*********************99 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.0   1.4e-06    0.0062      33      91 ..     224     281 ..     208     282 .. 0.88
   2 ?    1.9   0.0      0.06   2.7e+02      32      80 ..     360     411 ..     325     416 .. 0.71

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 1.4e-06
  ANAPC4_WD40  33 eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgWge 91 
                  e +++ +++  La +p+g+ La + +d ++ + dae+   +++++ ++++ +++l+++ 
   EEA22789.1 224 EPQGHTGTILTLAVSPSGRYLATGGEDKKLIIWDAETLAPMKTFTQHRDS-ISSLSFTR 281
                  55678899*****************************************5.***99975 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.06
  ANAPC4_WD40  32 l....eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvks 80 
                  +    +e+ +++ + ++a  p  ++ + + + g+++l +++++k +h+++ ++
   EEA22789.1 360 GesskKEEYQNNVIDCVAVVPPTHF-VTGSDSGSLSLWSIHKKKPLHTIQLAH 411
                  3555444445555556666665554.6788999**************999765 PP

>> WD40_like  WD40-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   1.2e-05     0.053       3      74 ..     232     310 ..     230     373 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.2e-05
   WD40_like   3 iYsidiskkgslilyGgkddkctvlkleslesvsivesfedSvi...fvkllddd....lilvvtlDGtillsllenee 74 
                 i ++ +s+ g +++ Gg+d+k+ + + e+l  +  +++ +dS+    f++ ++ +    ++  ++ D ti +  l+ + 
  EEA22789.1 232 ILTLAVSPSGRYLATGGEDKKLIIWDAETLAPMKTFTQHRDSISslsFTRHISSHssgeQLFSGSFDRTIKTWSLSAGG 310
                 567889***********************************98533377777766555567777777777777776655 PP

>> DUF885  Bacterial protein of unknown function (DUF885)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.4     2e-05     0.091      20      72 ..      80     142 ..      64     197 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2e-05
                 SHHHHHHHHHHHHHHHHHHCT.S-CCHHHHHHHHHHHHHHHHHHHHHHHHHS..........H CS
      DUF885  20 spaaeaaraarlraalaeldaaidrdklseerldldllrerleleletaeag..........y 72 
                  + a ++r+++++++l+ +++++d+++ ++  +d+dl+ erl+ ++++a+ +          +
  EEA22789.1  80 GETAAERRLKLAERYLENIREEVDEAGFDATEIDRDLIAERLKEDVDEAKGRifrkiasqlnF 142
                 45678999999**********************************966555566533333222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (631 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       767  (0.0427799); expected 358.6 (0.02)
Passed bias filter:                      484  (0.0269954); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.69u 0.25s 00:00:00.94 Elapsed: 00:00:00.46
# Mc/sec: 4132.54
//
Query:       EEA22790.1  [L=203]
Description: proteasome component Pre1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    6.4e-38  130.2   0.0    7.4e-38  129.9   0.0    1.0  1  Proteasome  Proteasome subunit


Domain annotation for each model (and alignments):
>> Proteasome  Proteasome subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  129.9   0.0   4.1e-42   7.4e-38       8     190 .]       5     184 ..       2     184 .. 0.95

  Alignments for each domain:
  == domain 1  score: 129.9 bits;  conditional E-value: 4.1e-42
                 EEEEETTEEEEEEEEEEEETTEEEESSSSTSEEEEETTEEEEEEESHHHHHHHHHHHHHHHHHHHHHHSSGTCHHHHHHHHHHHHHHHHHHCTTTTTSE CS
  Proteasome   8 vGikgkdgvvlaadkratagskllskstveKifkiddhigvafaGlaaDartlvrraraeaqlyrlrygrpipverlvarvaaklqaytqrsgrrpfgv 106
                 +Gi+gkd+v++aa k a +g ++l+ ++ +K + +++h+++af+G+ +D+ +++++++a++qly++r+++++++  +v ++++  +a  +rs r+p+ v
  EEA22790.1   5 LGITGKDFVIIAASKAAMRGPTVLKATD-DKTRNLNQHTLMAFSGEPGDGVQFAEYIQANVQLYSMRNDTELSPA-AVGNFVRGELARALRS-RNPYTV 100
                 8**********************99998.**********************************************.8889999999999988.99**** PP

                 EEEEEEEE.TTTEEEEEEEETTSEEEEESSEEEESTTHHHHHHHHHHHHSTTBSHHHHHHHHHHHHHHHHHHBTTSCSSEEEEEE CS
  Proteasome 107 slliagvd.eeggpeLyqidpsGsyieekdavaiGsgseaaktalekeykedltleeavelavkalkealerdklsgknievavi 190
                 +ll++gvd  +++p+Ly++d+ +s++e  +++a+G++++++ ++l+k+ ++d++le++++l   +  e+ +r  +  k++ v v+
  EEA22790.1 101 NLLLGGVDaITNTPSLYWVDYLASLAEV-PYAAHGYAQYYCLSILDKHHHPDIDLEQGLKLLNLCTDELKRRLPIDFKGVLVKVV 184
                 ********66899***************.6*****************************************99999999888775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (203 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       370  (0.020637); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.24s 00:00:00.62 Elapsed: 00:00:00.38
# Mc/sec: 1605.52
//
Query:       EEA22791.1  [L=612]
Description: snRNP assembly factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.5e-25   87.5   0.5      4e-24   85.5   0.0    2.0  2  UCH       Ubiquitin carboxyl-terminal hydrolase
    1.7e-12   47.4   0.8    3.1e-12   46.6   0.2    1.7  2  zf-UBP    Zn-finger in ubiquitin-hydrolases and other protein
      0.001   18.7   0.0      0.016   14.9   0.0    2.3  1  UCH_1     Ubiquitin carboxyl-terminal hydrolase
  ------ inclusion threshold ------
       0.61    9.2   5.6        1.1    8.4   5.6    1.3  1  Med3      Mediator complex subunit 3 fungal


Domain annotation for each model (and alignments):
>> UCH  Ubiquitin carboxyl-terminal hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.5   0.0   8.9e-28     4e-24       1     207 [.     219     490 ..     219     498 .. 0.89
   2 ?   -0.4   0.1      0.14   6.3e+02     230     255 ..     562     594 ..     547     596 .. 0.69

  Alignments for each domain:
  == domain 1  score: 85.5 bits;  conditional E-value: 8.9e-28
                 -EES-SSSTHHHHHHHHHHHTSHHHHHHHHTCHHCCSSTCCCCC-.TT.TTS.TTHHHHHHHHHHHHHH..SH-CCEE--HHHHHHHH.HHSGGGTSSS CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxx.xxxxxxxxxx RF
         UCH   1 tGlsNlGntCymnsvlQcLfsipelrdyllsleevkkesrnkkelnesnplgkkgelakalkdlfkell..kskskavsPkklkktls.klaksfsgyk 96 
                 +G++N+ ++ y+n v+Q+L+++ ++r+++l   ++  +             + + +l+ ++++l+++l+  k  +++vsP++l++ ++ +++k+f   +
  EEA22791.1 219 VGMNNIKANDYLNVVVQVLAHVTPIRNFFLL--QNFPV-------------PGSPQLSVRFSTLVRKLWnpKAFKSHVSPHELLQEIAlRSSKRFTLTH 302
                 69************************99998..22222.............223359************9977899******999887245666***** PP

                 TCEHHHHHHHHHHHHHHHHCCHCCCHHHHHHCCCTTSHHHHHH-EEEEE.................................................. CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.................................................. RF
         UCH  97 qqDaqEflaflLdqlhedlnrevaeekwkkhlkrndslitdlfegqlks.................................................. 145
                 q D  Efl+  L++lh  l         kk +k+++s+i++ f+g+l+                                                   
  EEA22791.1 303 QSDPVEFLSWFLNNLHLTLGG------SKKPSKAPTSVIQQAFQGHLRIesqaitahsdttnsrlvfaessetntqtspfliltldlpptplfqsanre 395
                 *******************99......7999****************9999************************************************ PP

                 .............................EEEEEEB-SEEEEEEESEEETEE.EEE--SEEB--S..EEE-GGGBSS-BTT.S-TCS-BEEEEEE CS
                 .............................xxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxx..xxxxxxxxxxxxxx.xxxxxxxxxxxxx RF
         UCH 146 .............................klklkrlPeiLiihlkRfsynss.ksKlntkvefpe..eldlssylaeekkk.kteekkkYeLiav 207
                                              +  l+ lP++L++h+kRfs n+  ++++ t v+fp   +ld+s+y++ + +  +  e  +Y+L++ 
  EEA22791.1 396 siipqiplttllnkyngitaseklshrvrHRLLHPLPPYLLFHIKRFSKNKFvSERNPTIVTFPSprSLDMSPYVEPNPQLwPPGEPIIYDLVSN 490
                 ****************************9999*******************************9555*******986543312334445777765 PP

  == domain 2  score: -0.4 bits;  conditional E-value: 0.14
                 E.......EEEEETTEEEEE-HHCCCTT.CEEEE CS
                 x.......xxxxxxxxxxxxxxxxxxxx.xxxxx RF
         UCH 230 k.......WykydDetvkevkeeeevls.sayiL 255
                 +       W+ ++D  v+++++e ++ + ++y++
  EEA22791.1 562 QaqqrgpeWLEIQDLYVQRTESE-TLFTrESYLM 594
                 13445667************977.4444577776 PP

>> zf-UBP  Zn-finger in ubiquitin-hydrolases and other protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.6   0.2   6.9e-16   3.1e-12       1      63 [.     118     179 ..     118     180 .. 0.95
   2 ?   -3.2   0.0       2.5   1.1e+04      24      42 ..     344     362 ..     338     369 .. 0.73

  Alignments for each domain:
  == domain 1  score: 46.6 bits;  conditional E-value: 6.9e-16
                 -TTTH--.SSEEEETTT--EEE-TTTT-HHHHHHHHH---EEEETTT--EEETTTTEEBE-GC CS
      zf-UBP   1 CseCnsenknlWlCLkCghvgCgrksnghalkHyeetrHplavdlstlsvycyscddevedke 63 
                 Cs++ s+  n+++CL Cg++++gr +++ha+ H+ e +H+++v+++t +vy +++ +ev++k+
  EEA22791.1 118 CSVSLSN-INVYACLVCGKYFQGRGNKSHAYFHALEIGHHVFVNMETKKVYVLPEGYEVKSKS 179
                 8899977.9**************************************************9875 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.5
                 TTTT-HHHHHHHHH---EE CS
      zf-UBP  24 rksnghalkHyeetrHpla 42 
                 r +++ +++H  +t+  l+
  EEA22791.1 344 RIESQAITAHSDTTNSRLV 362
                 5557899999999887666 PP

>> UCH_1  Ubiquitin carboxyl-terminal hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   3.5e-06     0.016       1     160 [.     219     364 ..     219     593 .. 0.60

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 3.5e-06
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       UCH_1   1 sGLEnhivnsYlNslLQvlyfipplrnl.alshlakeckkehcLlcElgflfdmldkak..glncqasnFlralssipeasalglileeeeetekssai 96 
                 +G+ n  +n YlN ++Qvl++++p+rn+ +l+ +    +    L+  +  l++ l + k  ++++  +++l+ +   +  +++ l  +++       ++
  EEA22791.1 219 VGMNNIKANDYLNVVVQVLAHVTPIRNFfLLQNF--PVPGSPQLSVRFSTLVRKLWNPKafKSHVSPHELLQEIALRS-SKRFTLTHQSD-------PV 307
                 799999********************65156666..888888888888888888877766577888888888877333.56666642221.......22 PP

                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       UCH_1  97 slssliqsfnrflldqlekelketkknsseeesaieqllgtkaettirclkCgseksrksstlv 160
                        +f  ++l++l+  l  +kk+s++ +s i+q ++ ++  +++ ++ +s ++++  ++ 
  EEA22791.1 308 -------EFLSWFLNNLHLTLGGSKKPSKAPTSVIQQAFQGHLRIESQAITAHSDTTNSRLVFA 364
                 .......355555555555555555555555555555555555555555533333333333333 PP

>> Med3  Mediator complex subunit 3 fungal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   5.6   0.00024       1.1     151     223 ..     496     565 ..     493     575 .. 0.64

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00024
        Med3 151 ttatPgantktaakslpapnatatigtptnsaaaaattatttssqakkPrkPrq.tkkaaakaaakaqaqaqaq 223
                  ++tPga+  t a++      +a+ g+  ++a++aatt   +++ + k     q   ka a+ +ak q+q+ +q
  EEA22791.1 496 NAPTPGAGEDTSAAADKG--LAAAGGAGNKNASSAATTG--AGAGSEKVSWLVQlHDKAMAAENAKHQQQQAQQ 565
                 589*****9998876555..3444455556777777777..444444555444416676666666666555444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (612 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       861  (0.0480228); expected 358.6 (0.02)
Passed bias filter:                      486  (0.0271069); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 4074.81
//
Query:       EEA22792.1  [L=774]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (774 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       489  (0.0272742); expected 358.6 (0.02)
Passed bias filter:                      427  (0.0238162); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.69u 0.27s 00:00:00.96 Elapsed: 00:00:00.46
# Mc/sec: 5080.82
//
Query:       EEA22793.1  [L=955]
Description: small nucleolar ribonucleoprotein complex subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.6e-54  179.9   8.7    1.1e-06   29.2   0.1   13.2 12  WD40         WD domain, G-beta repeat
    1.2e-48  164.6   0.2      2e-48  163.9   0.2    1.4  1  Utp13        Utp13 specific WD40 associated domain
    6.4e-13   48.8   0.6       0.12   12.7   0.0    7.2  6  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
     0.0012   17.8   0.2       0.15   11.0   0.0    3.9  6  Ge1_WD40     WD40 region of Ge1, enhancer of mRNA-decapping p


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.9   0.0     0.025   1.1e+02       2      35 ..      51      85 ..      50      87 .. 0.79
   2 !   29.2   0.1   2.5e-10   1.1e-06       3      38 .]     104     140 ..     102     140 .. 0.86
   3 !   12.2   0.0   5.7e-05      0.26       4      38 .]     147     210 ..     144     210 .. 0.83
   4 !   19.9   0.0   2.2e-07   0.00097       2      38 .]     215     252 ..     214     252 .. 0.91
   5 !    5.3   0.0    0.0088        40      25      38 .]     280     293 ..     265     293 .. 0.79
   6 ?    0.1   0.0      0.39   1.8e+03      18      36 ..     318     336 ..     304     338 .. 0.79
   7 !   20.0   0.2     2e-07   0.00089       7      37 ..     418     449 ..     413     450 .. 0.88
   8 !   10.3   0.0   0.00023         1       3      38 .]     460     512 ..     458     512 .. 0.76
   9 !   22.0   0.0   4.8e-08   0.00022       8      38 .]     530     561 ..     523     561 .. 0.92
  10 !   22.0   0.1   4.8e-08   0.00021       2      38 .]     566     617 ..     565     617 .. 0.81
  11 !   17.8   0.0   9.7e-07    0.0044       2      38 .]     622     677 ..     621     677 .. 0.90
  12 !    5.5   0.1    0.0077        35       5      37 ..     685     731 ..     681     732 .. 0.71

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.025
                EEEEEEESSSS.EEEEEEETTSSEEEEEETTSEEE CS
        WD40  2 qclrtltGHss.vtslafspdgawlasGsdDgtvr 35
                ++l +l+G +  +tsla  p+ + ++ +s+  + r
  EEA22793.1 51 NQLASLEGDGElITSLAITPSASHVVVCSRSMSMR 85
                6788888884479************9999766655 PP

  == domain 2  score: 29.2 bits;  conditional E-value: 2.5e-10
                 EEEEEESS.SSE..EEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGH.ssv..tslafspdgawlasGsdDgtvriWd 38 
                 +lrt ++H s+v  t+   +p g++la+G+ Dg++++Wd
  EEA22793.1 104 LLRTVKAHtSPVvtTA--IDPTGTLLATGGSDGSIKVWD 140
                 689*****88862555..5**********88*******9 PP

  == domain 3  score: 12.2 bits;  conditional E-value: 5.7e-05
                 EEEEESSSS.EEEEEEETTSSE..................................EEEEETTSEEEEEE CS
        WD40   4 lrtltGHss.vtslafspdgaw..................................lasGsdDgtvriWd 38 
                 ++t+ GH++ vt+l      ++                                  lasG++ g+vr+Wd
  EEA22793.1 147 THTFHGHGGvVTAL------NFfeaitnvdehngakrtkkqkdgeeeeteksitirLASGDEEGKVRVWD 210
                 799****7757999......6666666667777777889999999999999999999************9 PP

  == domain 4  score: 19.9 bits;  conditional E-value: 2.2e-07
                 EEEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 +++ +l+ H s v+sl++sp  + l+s+s+D+tv iWd
  EEA22793.1 215 KPIASLESHvSVVRSLSYSPVENALLSASRDKTVIIWD 252
                 68899****5558************************9 PP

  == domain 5  score: 5.3 bits;  conditional E-value: 0.0088
                 EEEEETTSEEEEEE CS
        WD40  25 lasGsdDgtvriWd 38 
                  ++G++ g +riWd
  EEA22793.1 280 CFTGGEQGVLRIWD 293
                 458**********9 PP

  == domain 6  score: 0.1 bits;  conditional E-value: 0.39
                 EETTSSEEEEEETTSEEEE CS
        WD40  18 fspdgawlasGsdDgtvri 36 
                 + p  +++++ + D+t+r+
  EEA22793.1 318 YAPGLPFVVTVHADQTLRL 336
                 5666699999999****98 PP

  == domain 7  score: 20.0 bits;  conditional E-value: 2e-07
                 EESSSS.EEEEEEETTSSEEEEEETTSEEEEE CS
        WD40   7 ltGHss.vtslafspdgawlasGsdDgtvriW 37 
                 l+GH + + +l+ + +g wla+G +D+t r+W
  EEA22793.1 418 LEGHEDiIICLDADWSGYWLATGAKDNTARLW 449
                 78**55468*********************** PP

  == domain 8  score: 10.3 bits;  conditional E-value: 0.00023
                 EEEEEESS.SSEEEEE................EETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGH.ssvtsla................fspdgawlasGsdDgtvriWd 38 
                 c  +ltGH  s  ++a                 ++  a++++Gs D+t++ Wd
  EEA22793.1 460 CAAVLTGHaESLGAIAlprtpppagskahndpLNHPPAFIFTGSQDRTIKKWD 512
                 66778888777777777788777777776666666667799***********9 PP

  == domain 9  score: 22.0 bits;  conditional E-value: 4.8e-08
                 ESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   8 tGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 ++H ++++sl+++   +++as+s D+tv+iW+
  EEA22793.1 530 KAHeKDINSLDVNYTATLFASASQDRTVKIWS 561
                 69*****************************5 PP

  == domain 10  score: 22.0 bits;  conditional E-value: 4.8e-08
                 EEEEEEESS.SSEEEEE..............EETTSSEEEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtsla..............fspdgawlasGsdDgtvriWd 38 
                 + +++l+GH  +v+s++              +s +  ++a+Gs D+tv+iW+
  EEA22793.1 566 SVVGVLRGHkRGVWSVRfsprempiissnagTSTSRGLIATGSGDKTVKIWN 617
                 56899****655****988888888777776666666699**88*******8 PP

  == domain 11  score: 17.8 bits;  conditional E-value: 9.7e-07
                 EEEEEEESS.SSEEEEEEETTSSE..................EEEEETTSEEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgaw..................lasGsdDgtvriWd 38 
                 +cl t++GH +sv  + + p +++                  las+  Dg v+iW+
  EEA22793.1 622 SCLLTFEGHtNSVLKVIWLPPSQLssendadgdesktqarplLASSAADGLVKIWS 677
                 79*******999****988888889999999999*******8787778*******5 PP

  == domain 12  score: 5.5 bits;  conditional E-value: 0.0077
                 EEEESS.SSEEEEE.EETTSSE............EEEEETTSEEEEE CS
        WD40   5 rtltGH.ssvtsla.fspdgaw............lasGsdDgtvriW 37 
                  tl+ H + v++la   p+g+             l+sG  D tv +W
  EEA22793.1 685 ATLDNHtDRVWALAsPTPSGSRsdvispsispysLISGAADSTVTFW 731
                 6788895559999995555555555566666667779*99*****99 PP

>> Utp13  Utp13 specific WD40 associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  163.9   0.2   4.5e-52     2e-48       1     142 []     753     925 ..     753     925 .. 0.98

  Alignments for each domain:
  == domain 1  score: 163.9 bits;  conditional E-value: 4.5e-52
                 -HHHHHHHHCCHHHHHHHHHHHSSSTHHHHHHHHHHHS-SS-..........-STSSSSSHHHHHHHHC--HHHHHHHHHHHHHHHTSTTTHHHHHHHH CS
       Utp13   1 eqelqnllrkkdyreAiaLAlkldqpkrllkllkevleseee..........eeesitgskevdevlkslskeqleklLkyirdWntnartsevAqrvL 89 
                 +q+lqn++r++ yreAi+LAl+l++p rll+l+++++++++            +++ tg+++vd+vl+sl++++l+ lL ++rdWntnart++vAqr+L
  EEA22793.1 753 DQQLQNYIRTGAYREAITLALQLNHPARLLSLFTAAIDESDGkksekdgdnnTDSELTGNSSVDQVLQSLDQDNLYLLLLRLRDWNTNARTAKVAQRIL 851
                 6************************************888779999999998889999999************************************** PP

                 HHHHHHS-HHHHHS--.....................-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHXXX CS
       Utp13  90 nailkslsaeellele.....................glkellealipYteRHlkRldrlveesylldytlqem 142
                 +++++s++a++ +el+                     +lke+ +al +Yt+RH++R+++lv+esyl++++l+em
  EEA22793.1 852 YTLVRSYPASTYIELAnrpppatatqgkrsrkdvgglSLKEIFNALSSYTDRHYRRVEELVDESYLVEWILDEM 925
                 ************************************************************************99 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.7   0.0   2.6e-05      0.12      35      89 ..     109     162 ..      95     165 .. 0.86
   2 !    9.1   0.0   0.00036       1.6      19      73 ..     206     259 ..     195     273 .. 0.72
   3 ?    2.5   0.0     0.041   1.8e+02       5      24 ..     375     394 ..     370     456 .. 0.69
   4 !   10.8   0.0    0.0001      0.46      33      81 ..     528     576 ..     511     585 .. 0.84
   5 ?   -1.2   0.0       0.6   2.7e+03      52      89 ..     603     639 ..     599     641 .. 0.85
   6 ?    2.3   0.0     0.046   2.1e+02      52      81 ..     663     692 ..     658     699 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 2.6e-05
  ANAPC4_WD40  35 dkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                  +++ s v   a  p g+lLa + sdg++++ d+  g + h+++ +    vt l++
   EEA22793.1 109 KAHTSPVVTTAIDPTGTLLATGGSDGSIKVWDIRGGFITHTFHGHGG-VVTALNF 162
                  5667788888899*****************************98877.5888887 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.00036
  ANAPC4_WD40  19 llvfRlngqrvwtl.......eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvv 73 
                  ++v          l       + +++ s vrsL+++p ++ L  a  d +v + da + k  
   EEA22793.1 206 VRVWD--------LhkkkpiaSLESHVSVVRSLSYSPVENALLSASRDKTVIIWDARTWKSR 259
                  44444........333333333477888999********************99999887765 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.041
  ANAPC4_WD40   5 ptmDLiAlatedgellvfRl 24 
                  p++ L+A+at++++++v  +
   EEA22793.1 375 PERSLLAMATNTESIRVVSI 394
                  78899999999999998655 PP

  == domain 4  score: 10.8 bits;  conditional E-value: 0.0001
  ANAPC4_WD40  33 eedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvkse 81 
                  +++++++ ++sL  +   +l+a a +d +v++ +ae+g vv  l+ ++ 
   EEA22793.1 528 TRKAHEKDINSLDVNYTATLFASASQDRTVKIWSAEDGSVVGVLRGHKR 576
                  4588999*********************************988877665 PP

  == domain 5  score: -1.2 bits;  conditional E-value: 0.6
  ANAPC4_WD40  52 lLavaysdgevrlldaesgkvvhslsvksekavtclgW 89 
                  l+a +  d +v++ +  +  ++ +++ ++++ v ++ W
   EEA22793.1 603 LIATGSGDKTVKIWNLADFSCLLTFEGHTNS-VLKVIW 639
                  6889999999999999999999999988885.888877 PP

  == domain 6  score: 2.3 bits;  conditional E-value: 0.046
  ANAPC4_WD40  52 lLavaysdgevrlldaesgkvvhslsvkse 81 
                  lLa + +dg v++ + +sg+   +l+ +++
   EEA22793.1 663 LLASSAADGLVKIWSPYSGESEATLDNHTD 692
                  89*****************99888887776 PP

>> Ge1_WD40  WD40 region of Ge1, enhancer of mRNA-decapping protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.0   0.0   3.4e-05      0.15     183     216 ..     107     141 ..      66     171 .. 0.83
   2 ?   -1.2   0.0      0.17   7.5e+02     230     287 ..     209     266 ..     194     272 .. 0.66
   3 ?   -3.8   0.0       1.1   4.8e+03      65     102 ..     364     401 ..     360     405 .. 0.76
   4 ?   -2.0   0.0      0.29   1.3e+03     252     275 ..     540     563 ..     517     572 .. 0.73
   5 ?    0.7   0.0     0.045     2e+02     257     284 ..     601     628 ..     591     657 .. 0.81
   6 ?   -2.5   0.0      0.41   1.9e+03     202     221 ..     664     683 ..     661     693 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 3.4e-05
    Ge1_WD40 183 kieehs.liveaafspdGtalatasedGevkffqv 216
                  ++ h+  +v++a+ p Gt lat  +dG +k + +
  EEA22793.1 107 TVKAHTsPVVTTAIDPTGTLLATGGSDGSIKVWDI 141
                 356664389************************98 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.17
    Ge1_WD40 230 WkPhdGkslssllfldnhkeesdeqfWrfaitgadnnselklWscelWtClqtikfap 287
                 W  h+ k+++sl     + ++   +    a+ +a++++ + +W + +W+  + i +  
  EEA22793.1 209 WDLHKKKPIASLESHVSVVRSLSYSPVENALLSASRDKTVIIWDARTWKSRRIIPVLE 266
                 6667777777765555555544455556667777778888888888888777766655 PP

  == domain 3  score: -3.8 bits;  conditional E-value: 1.1
    Ge1_WD40  65 kgevldlafahvsskillavdekgslfvykveeveskl 102
                  +ev dla+   +++ l+   ++ s+ v +++  +++ 
  EEA22793.1 364 DDEVIDLAYVGPERSLLAMATNTESIRVVSITVPDQNA 401
                 56888998888888888888888888888887766655 PP

  == domain 4  score: -2.0 bits;  conditional E-value: 0.29
    Ge1_WD40 252 deqfWrfaitgadnnselklWsce 275
                 d+++   + ++a++++ +k+Ws+e
  EEA22793.1 540 DVNYTATLFASASQDRTVKIWSAE 563
                 455555556677777777888776 PP

  == domain 5  score: 0.7 bits;  conditional E-value: 0.045
    Ge1_WD40 257 rfaitgadnnselklWscelWtClqtik 284
                 r +i++ + ++ +k+W+   ++Cl t +
  EEA22793.1 601 RGLIATGSGDKTVKIWNLADFSCLLTFE 628
                 5567777888999**********99875 PP

  == domain 6  score: -2.5 bits;  conditional E-value: 0.41
    Ge1_WD40 202 latasedGevkffqvylede 221
                 la +++dG+vk +  y  ++
  EEA22793.1 664 LASSAADGLVKIWSPYSGES 683
                 78888888888887776554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (955 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       502  (0.0279993); expected 358.6 (0.02)
Passed bias filter:                      412  (0.0229795); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.76u 0.35s 00:00:01.10 Elapsed: 00:00:00.51
# Mc/sec: 5611.36
//
Query:       EEA22794.1  [L=473]
Description: G-patch domain protein (Spp2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.5e-24   85.8   0.5    5.8e-24   84.0   0.3    2.2  2  G-patch_2  G-patch domain
    0.00081   19.2   0.3     0.0022   17.8   0.3    1.8  1  G-patch    G-patch domain


Domain annotation for each model (and alignments):
>> G-patch_2  G-patch domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.4   0.0       1.3   1.1e+04      26      43 ..      68      85 ..      68      92 .. 0.73
   2 !   84.0   0.3   6.5e-28   5.8e-24       1      59 [.     220     282 ..     220     284 .. 0.97

  Alignments for each domain:
  == domain 1  score: -3.4 bits;  conditional E-value: 1.3
   G-patch_2 26 GWkegqgigknkkgrvkp 43
                G++ g +i+kn+ ++++p
  EEA22794.1 68 GFDMGGAISKNAPKEKEP 85
                788889999997666555 PP

  == domain 2  score: 84.0 bits;  conditional E-value: 6.5e-28
   G-patch_2   1 peeasleeyeevPVeeFGaAlLrGMGWkegqgigknkkgr....vkpeepkrRpgrlGLGakp 59 
                 p++asl++ye+vPVeeFGaAlLrGMGWkegq+ig+  +g+    +++++p rRpg+lG+Gak+
  EEA22794.1 220 PDQASLDAYEAVPVEEFGAALLRGMGWKEGQAIGRGDYGDttaaKEARVPARRPGFLGIGAKD 282
                 899*************************************9999999**************97 PP

>> G-patch  G-patch domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.8   0.3   2.5e-07    0.0022       4      33 ..     236     265 ..     234     281 .. 0.75

  Alignments for each domain:
  == domain 1  score: 17.8 bits;  conditional E-value: 2.5e-07
     G-patch   4 iGvkmLqkmGWkpGqGLGkkeqGiaePiea 33 
                 +G+ +L+ mGWk+Gq +G+   G +++ + 
  EEA22794.1 236 FGAALLRGMGWKEGQAIGRGDYGDTTAAKE 265
                 799***************988887776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (473 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       572  (0.0319036); expected 358.6 (0.02)
Passed bias filter:                      358  (0.0199677); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 3153.24
//
Query:       EEA22795.1  [L=513]
Description: HET-s/LopB domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
     0.0075   15.7   0.0      0.016   14.6   0.0    1.5  1  Pkinase      Protein kinase domain
  ------ inclusion threshold ------
      0.077   12.3   0.0        1.1    8.5   0.0    2.1  2  Pkinase_Tyr  Protein tyrosine kinase


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.0   1.8e-06     0.016      84     190 ..     294     410 ..     257     424 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 1.8e-06
                 BHHHHHHHHSS--HHHHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTE.....EEE-SGTTSEESSSSCS..BCTTTSCGGGS-HHHH...TTS CS
     Pkinase  84 eladllerkgslseeeakkiakqilegleylHskgiiHrDlKpeNiLidekge.....lKitDFGlakelesssk..ltsfvgtseYlAPEvl...ken 172
                 +l dll +  +++ ++  ++ak++++++ ++H  g++H+ + p+ i + ++         ++ F   + +  +s+   + +  t  Y+ P+      e 
  EEA22795.1 294 TLRDLLLHGATYPLDQRFQLAKKLARSVTFVHTYGFVHKNIRPDTIVVFQDHSsvlghSFLVGFERFRPAAAGSQlqGDPRWETNLYRHPRRQgsrPED 392
                 57777776677888888899***************************996555566666677777777777777665778899*********9664447 PP

                 CBSHHHHHHHHHHHHHHH CS
     Pkinase 173 eyskkvDvWslGvilyel 190
                  y  + D++slGv l+e+
  EEA22795.1 393 TYIMQHDIYSLGVCLLEF 410
                 78999*********9986 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.0   0.00012       1.1      95     139 ..     191     344 ..     100     356 .. 0.63
   2 ?    1.5   0.0     0.017   1.5e+02     180     198 ..     392     410 ..     384     417 .. 0.87

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00012
                  T................................................................................................. CS
  Pkinase_Tyr  95 k................................................................................................. 95 
                  k                                                                                                 
   EEA22795.1 191 Ksifidgrsieglrqhlslyttyvshmhdgqavlidtityppgtnmstaiihvrdlaivlsnadpevfgllachgvvaianeqaessqfqfvfaippg 288
                  05555555555555555555555555555555555555555555555555555555555555566666666666666666666666666666666666 PP

                  ............CTTTSBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEET CS
  Pkinase_Tyr  96 ............ekekltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsen 139
                              + ++  l++ +++a ++A+ + ++++  +vH++++   +++ ++
   EEA22795.1 289 lfnprtlrdlllHGATYPLDQRFQLAKKLARSVTFVHTYGFVHKNIRPDTIVVFQD 344
                  66666666666667888999**************************9999888665 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.017
                  SEEEHHHHHHHHHHHHHHH CS
  Pkinase_Tyr 180 kkftsksDvWsfGvllwEi 198
                   ++  + D++s Gv+l E 
   EEA22795.1 392 DTYIMQHDIYSLGVCLLEF 410
                  5688899*********995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (513 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       626  (0.0349155); expected 358.6 (0.02)
Passed bias filter:                      585  (0.0326287); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.26s 00:00:00.87 Elapsed: 00:00:00.43
# Mc/sec: 3566.62
//
Query:       EEA22796.1  [L=537]
Description: serine/threonine-protein kinase chk2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      1e-52  179.2   0.0    1.3e-52  178.8   0.0    1.1  1  Pkinase          Protein kinase domain
    8.2e-21   74.4   0.0      3e-20   72.6   0.0    1.8  2  Pkinase_Tyr      Protein tyrosine kinase
    4.9e-09   35.9   0.0      8e-09   35.2   0.0    1.2  1  Kinase-like      Kinase-like
     0.0008   18.3   0.0     0.0012   17.7   0.0    1.2  1  Pkinase_fungal   Fungal protein kinase
  ------ inclusion threshold ------
      0.013   14.9   0.0      0.024   14.0   0.0    1.4  1  Kdo              Lipopolysaccharide kinase (Kdo/WaaP) family
      0.073   12.0   0.0       0.11   11.4   0.0    1.2  1  Pox_ser-thr_kin  Poxvirus serine/threonine protein kinase


Domain annotation for each model (and alignments):
>> Pkinase  Protein kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  178.8   0.0   4.2e-56   1.3e-52       2     263 ..      42     301 ..      41     302 .. 0.88

  Alignments for each domain:
  == domain 1  score: 178.8 bits;  conditional E-value: 4.2e-56
                 EEEEEEEEESSEEEEEEEETTTTEEEEEEEEECHCHCHHHHHHHHHHHHHHHHHS..CTTB--EEEEEEESSEEEEEEE--TTEBHHHHHHHHSS--HH CS
     Pkinase   2 ekleklGeGsfGkVykaveketgkivAvKkikkekakkkkekkvlrEikilkklk..hpnivrlyevfeekdelylvleyveggeladllerkgslsee 98 
                 +++e++G G+ G+V++++ ++ g+  A+K i+k ++++ +   +++E+  + +l+   +  v+ly+++e+++ lyl +ey+e g++   +    ++se 
  EEA22796.1  42 RRHERIGAGAGGEVFEVR-SNLGNVRAIKAIRKPENSDLSS--YIKELVAMGQLSkdNDLFVELYGWYESDQFLYLAMEYLELGHIGMCYP--DCMSEL 135
                 57899*************.799************9999775..***********9666679***********************8888886..69**** PP

                 HHHHHHHHHHHHHHHHHHTTEE-SS-SGGGEEEETTTE..EEE-SGTTSEESSSSCS.BCTTTSCGGGS-HHHH.......TTSCBSHHHHHHHHHHHH CS
     Pkinase  99 eakkiakqilegleylHskgiiHrDlKpeNiLidekge..lKitDFGlakelesssk.ltsfvgtseYlAPEvl.......keneyskkvDvWslGvil 187
                 +++ +akq+leg++ +H+kgiiHrD+Kp+NiL+ +k+   +Ki+DFG +k ++++++  +s vgt+++ APE+l       +++ey+++vD+Ws+G++l
  EEA22796.1 136 DVRIVAKQLLEGVAKMHEKGIIHRDIKPQNILVFQKDPiwIKIGDFGSSKVIQKNESgPNSLVGTENFAAPEILqlldnapETSEYTNAVDLWSVGCVL 234
                 **********************************666689*************99999****************999998888**************** PP

                 HHHHHSS-STTTSSHHHHHHHHHHTHHHHHHHCT.SHH...HHHTTS-HHHHHHHHHHT-SSGCCSTTHHHHHTSGG CS
     Pkinase 188 yelltgkppfsgekgkekvekeldqlekilkilg.etkeklpeaseiseeakdllkkllkkdpkkRltaeellqhpy 263
                 y ll+++ pf+   + +  + e       +++          +++++s++ ++++++l++++p++R++a+ +l   +
  EEA22796.1 235 YYLLSRNLPFP---SVKLLY-E------YCRVKMrRFPDYHLRDKNVSSSGISFIRNLMAREPSERMSASTALVTAW 301
                 ***********...222222.2......2222221333445678999***********************9998887 PP

>> Pkinase_Tyr  Protein tyrosine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.6   0.0     1e-23     3e-20       4     251 ..      44     292 ..      41     300 .. 0.79
   2 ?    0.9   0.0     0.077   2.3e+02     154     188 ..     284     318 ..     267     321 .. 0.81

  Alignments for each domain:
  == domain 1  score: 72.6 bits;  conditional E-value: 1e-23
                  EEEEEEESSEEEEEEEEETTTTSSEEEEEEEEESTTSSHHHHHHHHHHHHHHHTS..-BTTB--EEEEEESSSSEEEEEE--TTEBHHHHHHHTCTTT CS
  Pkinase_Tyr   4 gkklGeGafGkVvegtlkgekekkevkVavKtlkeeateeekeelleeakimkkl..khpnivkllgvctkeepllivteyvkgGdLlkfLrkkekek 99 
                  ++++G+Ga G+V+e + +          a+K +++  +++  ++ ++e+  m +l  +++  v+l+g++ +++ l++ +ey++ G++     +     
   EEA22796.1  44 HERIGAGAGGEVFEVRSN-----LGNVRAIKAIRKPENSD-LSSYIKELVAMGQLskDNDLFVELYGWYESDQFLYLAMEYLELGHIGMCYPDC---- 131
                  689***********9988.....455569****7776666.99************5444458************************99887776.... PP

                  SBHHHHHHHHHHHHHHHHHHHHTTEEEST-SGGGEEEEETT..EEEE-STTTHEETTTSSEEEETTSSTSGGGGS-HHHHHHSE.......EEHHHHH CS
  Pkinase_Tyr 100 ltlkdllsfalqvAkGmeyLeskklvHrdlaarNvLlsenk..vvkisDfGLardiekddeyvkkeeaklpvkWmapEslkekk.......ftsksDv 188
                  ++  d+  +a q+ +G++ +++k ++Hrd+  +N+L+ +++   +ki+DfG ++ i  +++ +  ++     ++ apE+l+          +t + D 
   EEA22796.1 132 MSELDVRIVAKQLLEGVAKMHEKGIIHRDIKPQNILVFQKDpiWIKIGDFGSSKVI--QKNESGPNSLVGTENFAAPEILQLLDnapetseYTNAVDL 227
                  7777888899***************************98665589***********..555556677788899******986666677778******* PP

                  HHHHHHHHHHHTTSSGTTTTSHHHHHHHHHHTTEE...S-BBTTSBHHHHHHHHHHT-SSGGGS-- CS
  Pkinase_Tyr 189 WsfGvllwEiftlgespypglkneevleklkegkr...lekpekcpeelyelmkkcweedpeeRpt 251
                  Ws G +l+ +++  + p+p++k    + ++k ++      + ++++++  +++++ ++++p+eR +
   EEA22796.1 228 WSVGCVLYYLLS-RNLPFPSVKLLYEYCRVKMRRFpdyHLRDKNVSSSGISFIRNLMAREPSERMS 292
                  **********99.67888888654433333322111113344556666666677777777777765 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.077
                  TTSSEEEETTSSTSGGGGS-HHHHHHSEEEHHHHH CS
  Pkinase_Tyr 154 ekddeyvkkeeaklpvkWmapEslkekkftsksDv 188
                   ++ + +++ ++ l   W+a E+ + ++   +sD+
   EEA22796.1 284 AREPSERMSASTALVTAWVADETTFPQRHAIASDI 318
                  3455668899999*******************997 PP

>> Kinase-like  Kinase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.2   0.0   2.7e-12     8e-09     151     253 ..     142     247 ..     133     260 .. 0.84

  Alignments for each domain:
  == domain 1  score: 35.2 bits;  conditional E-value: 2.7e-12
  Kinase-like 151 lqlirlaanLqakglvhgkftvdnllldekggl..mlggfta..Lvragtkvvlseve.kgfaPpEllgsrggytrknktkmthkldaWqlGlviyri 243
                   ql+  +a++++kg++h +++++n+l  +k ++  ++g+f++   +++ ++++ s v  + fa pE+l         ++ ++t ++d W +G v y++
   EEA22796.1 142 KQLLEGVAKMHEKGIIHRDIKPQNILVFQKDPIwiKIGDFGSskVIQKNESGPNSLVGtENFAAPEILQLLDN--APETSEYTNAVDLWSVGCVLYYL 237
                  5777889*******************99998862278999642288899999977776899*******99665..5599******************* PP

  Kinase-like 244 wclklPltla 253
                   +++lP+  +
   EEA22796.1 238 LSRNLPFPSV 247
                  ******9765 PP

>> Pkinase_fungal  Fungal protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.7   0.0   4.1e-07    0.0012     317     387 ..     146     210 ..     138     238 .. 0.75

  Alignments for each domain:
  == domain 1  score: 17.7 bits;  conditional E-value: 4.1e-07
  Pkinase_fungal 317 kghrsLflkagiLHrDiSenNilitdskkegerkgl.LiDLDlakelsddssesgarertGTleFmaievlk 387
                     +g  +++ ++gi+HrDi  +Nil+     ++++ ++ + D+   k ++  ++esg++  +GT +F a e+l+
      EEA22796.1 146 EGVAKMH-EKGIIHRDIKPQNILVF----QKDPIWIkIGDFGSSKVIQ--KNESGPNSLVGTENFAAPEILQ 210
                     5666778.9****************....4466665266888888888..699999**************99 PP

>> Kdo  Lipopolysaccharide kinase (Kdo/WaaP) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   8.1e-06     0.024     129     155 ..     146     172 ..     129     190 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 8.1e-06
         Kdo 129 rliaklhragvnHadlyaknillqqee 155
                   +ak+h+ g+ H+d+ ++nil+ q++
  EEA22796.1 146 EGVAKMHEKGIIHRDIKPQNILVFQKD 172
                 5699******************98876 PP

>> Pox_ser-thr_kin  Poxvirus serine/threonine protein kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   3.8e-05      0.11     299     324 ..     155     179 ..     144     189 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 3.8e-05
  Pox_ser-thr_kin 299 nflhvDlkPdniLifdskekliikvk 324
                        +h D+kP+niL+f+   ++ ik++
       EEA22796.1 155 GIIHRDIKPQNILVFQK-DPIWIKIG 179
                      579************85.56777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (537 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       447  (0.0249317); expected 358.6 (0.02)
Passed bias filter:                      400  (0.0223102); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.60u 0.27s 00:00:00.87 Elapsed: 00:00:00.45
# Mc/sec: 3600.42
//
Query:       EEA22797.1  [L=341]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.1e-17   62.2   0.2    6.8e-17   61.8   0.2    1.2  1  NmrA            NmrA-like family
    6.3e-15   55.5   0.2      1e-14   54.9   0.2    1.3  1  NAD_binding_10  NAD(P)H-binding
    4.2e-06   26.4   0.0    6.9e-06   25.7   0.0    1.4  1  Epimerase       NAD dependent epimerase/dehydratase family
    0.00085   19.4   0.1     0.0016   18.6   0.1    1.4  1  DapB_N          Dihydrodipicolinate reductase, N-terminus
     0.0034   17.8   0.3     0.0065   16.9   0.3    1.4  1  Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domai
      0.009   15.0   0.0      0.014   14.4   0.0    1.2  1  3Beta_HSD       3-beta hydroxysteroid dehydrogenase/isomerase
  ------ inclusion threshold ------
      0.013   14.7   0.2      0.018   14.2   0.2    1.2  1  RmlD_sub_bind   RmlD substrate binding domain
      0.031   14.3   0.1      0.052   13.6   0.1    1.3  1  Shikimate_DH    Shikimate / quinate 5-dehydrogenase
       0.06   13.9   1.8       0.14   12.8   1.4    1.9  2  F420_oxidored   NADP oxidoreductase coenzyme F420-dependent
        0.1   12.5   0.1       0.17   11.8   0.1    1.4  1  KR              KR domain
       0.11   11.7   0.1       0.23   10.6   0.1    1.6  1  NAD_binding_4   Male sterility protein
       0.11   12.4   0.3        0.2   11.6   0.3    1.4  1  DUF1348         Protein of unknown function (DUF1348)


Domain annotation for each model (and alignments):
>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.8   0.2   4.6e-20   6.8e-17       1     150 [.      20     165 ..      20     194 .. 0.88

  Alignments for each domain:
  == domain 1  score: 61.8 bits;  conditional E-value: 4.6e-20
                 EEESSTTSHHHHHHHHHHHH.HT-EEEEEES-S-SHHHHHHHHSTTEEE.ES-TT-HHHHHHHHTT-SEEEE---GGS-HHHHHHHHHHHHHHHS-SEE CS
        NmrA   1 IlviGaTGrqGksvvrallk.aghkvralvRdtkselakslkeaGvelv.kgdlddkeslvealkgvdvvfsvtgfyskeiedgkklvdAakeaGvkhf 97 
                 I+v+Ga G+ Gk++v+al++  +hkv al+R+ +s+++     aGv  + k d  + + ++ alkg d+ +++++     +e+  kl +Aa+eaGvk +
  EEA22797.1  20 IAVVGAGGQVGKYIVEALIAnGKHKVTALTREGSSNTIP----AGVHAIrKIDYAQPSTIADALKGQDALICTLS--VRATEEAEKLSRAAAEAGVKWI 112
                 89****************99678************9995....8*******************************..88899999************** PP

                 EEEE---GG.GT.SSS---TTTHHHHHHHHHHHHCTS-EEE.EEE-EEGGG-BS CS
        NmrA  98 iySslgddndrsnaeepavphfdsKaeieeyvralgipytf.vyagffmenfls 150
                 +++++g+ ++  + +  ++ +  +K + ++ +++l + + + +++gf++e+ ls
  EEA22797.1 113 LPNEFGNSKNSEQIDR-EIIIGVKKGQDRKLIEELAVSSWIgIATGFWYEYSLS 165
                 ********97776666.8888888889999999887776663456666666665 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.9   0.2   6.7e-18     1e-14       1      93 [.      24     112 ..      24     132 .. 0.90

  Alignments for each domain:
  == domain 1  score: 54.9 bits;  conditional E-value: 6.7e-18
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHHCTTTCE.EEE--TT-CCHHHHHHTT-SEEEES---TCCHHHHHHHHHHHHHHCT--EE CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpeklaeleaeegle.vvegdvtdvedlaealkgadaVvsalggggkdeegaknivdaakeagvkRf 93 
                     GA G+vG+++v+ l+a+g+h+vtal+R+ ++ + ++  +g++ + ++d  +++++a+alkg+da +++l+ +++  e a+++ +aa eagvk +
      EEA22797.1  24 GAGGQVGKYIVEALIANGKHKVTALTREGSSNT-IP--AGVHaIRKIDYAQPSTIADALKGQDALICTLSVRAT--EEAEKLSRAAAEAGVKWI 112
                     9***************************99988.76..56661556************************9997..68*************966 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.7   0.0   4.6e-09   6.9e-06       1      69 [.      20      86 ..      20     122 .. 0.84

  Alignments for each domain:
  == domain 1  score: 25.7 bits;  conditional E-value: 4.6e-09
                EEEETTTSHHHHHHHHHHHHCT.SEEEEEES-STTTTCHHCHHCEEEE--TT-HHHHHHHHHHHT-SEEE CS
   Epimerase  1 ilVtGatGfiGsalvkallekg.yevigldrlssasntarledlelveldltdrsalerlfkeeqpdavi 69
                i V+Ga G++G+++v+al ++g ++v++l+r+ s++   +  +  + ++d+ ++s +++++k  + da i
  EEA22797.1 20 IAVVGAGGQVGKYIVEALIANGkHKVTALTREGSSNTIPAGVH-AIRKIDYAQPSTIADALK--GQDALI 86
                68********************899*******66666554444.899999999999999999..556655 PP

>> DapB_N  Dihydrodipicolinate reductase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.1     1e-06    0.0016       2      72 ..      19      86 ..      18     114 .. 0.73

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 1e-06
                EEEEETTTSHHHHHHHHHHHHSTTEEEEEEEETTCSTTTTTBHHHHSSSS--S-BEBSSHHHHHHH-SEEE CS
      DapB_N  2 kvavvGasGrmGkevvkaveeaedlelvaavdrkeselegkdagellglgklgvavtddleevlekadvli 72
                ++avvGa G +Gk +v+a+ ++ +++++a   + +s+++   ag +  ++k+++a  ++++++l+ +d li
  EEA22797.1 19 NIAVVGAGGQVGKYIVEALIANGKHKVTALTREGSSNTI--PAG-VHAIRKIDYAQPSTIADALKGQDALI 86
                69*******************999999988877775443..333.45677899999999999999999776 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.3   4.4e-06    0.0065       1      94 [.      19     112 ..      19     113 .. 0.70

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 4.4e-06
                     EEEEETTTSHHHHHHHHHHHCTSSEEEEEEEESTTTTTSBHHHHSGGGTTTECEBEEEGGGGGCTT-SEEEE-SC...HHHHHHHHHHHHHTTSE CS
  Semialdhyde_dh   1 kvaivGatGyvGqellrlLeehpevelvvllsssrsaGkklaeavkaleegkdlkvedvdeeelkevdivflalp...agvskelapklaeagvk 92 
                     ++a+vGa G vG+ +++ L  + + ++++l+ + +   +  a ++  ++++   + + + +++lk+ d +++ l+    + +++l +++aeagvk
      EEA22797.1  19 NIAVVGAGGQVGKYIVEALIANGKHKVTALTREGS-SNTIPAGVHA-IRKIDYAQPS-TIADALKGQDALICTLSvraTEEAEKLSRAAAEAGVK 110
                     69*******************99999999887666.4444444444.4444444444.4667778888888776611145556677788999999 PP

                     EE CS
  Semialdhyde_dh  93 vi 94 
                     +i
      EEA22797.1 111 WI 112
                     98 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.0   9.3e-06     0.014       1      78 [.      21      93 ..      21     106 .. 0.83

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 9.3e-06
   3Beta_HSD  1 vvtGgaGFlGralvkeLvrleelkevrvlDlrespelleelskvnvkkviegDvtdkdkleealegvdvvihlaslvd 78
                +v+G++G +G+++v++L+  ++ ++v +l  + s+    ++   +v+ + + D  + +++ +al+g d++i + s+  
  EEA22797.1 21 AVVGAGGQVGKYIVEALIANGK-HKVTALTREGSS----NTIPAGVHAIRKIDYAQPSTIADALKGQDALICTLSVRA 93
                59******************95.777776444333....46788888899*********************9987765 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.2   1.2e-05     0.018       2      75 ..      19     105 ..      18     111 .. 0.84

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 1.2e-05
                    EEEEESTTSHHHHHHHHHCTTTS.EEEEEE-TT..............T--TTSHHHHHHHHHHH--SEEEE------HHHHHHSHHHHH CS
  RmlD_sub_bind   2 kilvtGanGqlGseLakqlaeeg.levlaltre..............eldltdaeavaellkeakpdvvvnaAAytavDkaEseeeaay 75 
                    +i v+Ga+Gq+G+ ++++l ++g ++v+altre              ++d ++++++a++lk    d+++ +   +a  +aE+ ++aa+
     EEA22797.1  19 NIAVVGAGGQVGKYIVEALIANGkHKVTALTREgssntipagvhairKIDYAQPSTIADALKG--QDALICTLSVRATEEAEKLSRAAA 105
                    689************9998775526899*****9************99***********9998..566777777788888888766665 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   3.5e-05     0.052      13      84 ..      18      90 ..       7     110 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 3.5e-05
                  -EEEEES-S.HHHHHHHHHHHCCT-CEEEEEESSHHHHHHHHHHHT.ET-EEEEGCGHHHHHHT-SEEEE-SS CS
  Shikimate_DH 13 kkvlliGaG.emaelvakhLlakgvkkvvvaNRtlerakelaeelkgeeiealkleelkellaeadvvisata 84
                  +++ ++GaG ++++ ++++L+a+g +kv+ + R+ +     a  +   +i + + + + ++l+  d +i+  +
    EEA22797.1 18 ENIAVVGAGgQVGKYIVEALIANGKHKVTALTREGSSNTIPAGVHAIRKIDYAQPSTIADALKGQDALICTLS 90
                  6899****6489**********************999998888888899999999999999999999997544 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   1.4   9.2e-05      0.14       2      77 ..      20      97 ..      19     112 .. 0.67
   2 ?   -0.1   0.1      0.97   1.4e+03      33      47 ..      91     105 ..      73     150 .. 0.56

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 9.2e-05
                   EEEE.TTSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC.....-EEECECHHHHHHH-SEEEE-S-HHHHHHH CS
  F420_oxidored  2 igii.GaGnmgealasgllaagaqpheivvansrnpekaeelaeelg.....vkvtavdneeaaeeadvvvlavkpedveev 77
                   i+++ ++G++g+ +++ l+a+g  +h+++ a +r+ ++ + + + +        +++++ ++a++ +d ++ ++  +++ee+
     EEA22797.1 20 IAVVgAGGQVGKYIVEALIANG--KHKVT-ALTREGSSNT-IPAGVHairkiDYAQPSTIADALKGQDALICTLSVRATEEA 97
                   999955689*************..99999.6565543322.21111122233346667788888888888888777777765 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.97
                    ESSCCCHHHHHHHHC CS
  F420_oxidored  33 srnpekaeelaeelg 47 
                     r  e+ae+l +++ 
     EEA22797.1  91 VRATEEAEKLSRAAA 105
                    444444444443332 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.1   0.00012      0.17       5      48 ..      22      64 ..      19     109 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00012
                EETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHH CS
          KR  5 itGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliael 48
                ++G+ G++G+ +++ l+++g++++  l+R+++ +++  a ++++
  EEA22797.1 22 VVGAGGQVGKYIVEALIANGKHKVTALTREGS-SNTIPAGVHAI 64
                89****************************63.33333333333 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.1   0.00016      0.23       2      37 ..      23      57 ..      22      80 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00016
                   E-TTSHHHHHHHHHHHHHS-.TEEEEEE-SSSHHHH CS
  NAD_binding_4  2 TGaTGFLGkvLlekLLrttpevkiyllvRaksgesa 37
                    Ga G +Gk+++e L+ + ++ k+++l R+ s++++
     EEA22797.1 23 VGAGGQVGKYIVEALIANGKH-KVTALTREGSSNTI 57
                   69****************987.*******9998765 PP

>> DUF1348  Protein of unknown function (DUF1348)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.3   0.00013       0.2      36     108 ..     110     186 ..      90     195 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00013
     DUF1348  36 vWrnrdeflk..greeiveflkkkwekeldyrlikelfaftdnriavrfayeykdesgqwfrsyGnen..WefdeeG 108
                 +W   +ef +    e+i + +    +k +d +li el   +   ia  f+yey+ ++g+w   +   n   +f ++G
  EEA22797.1 110 KWILPNEFGNskNSEQIDREIIIGVKKGQDRKLIEELAVSSWIGIATGFWYEYSLSAGEWSYGFDIKNraVTFYDDG 186
                 56555555440044677777777889999**********9********************76665443114565655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (341 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       372  (0.0207485); expected 358.6 (0.02)
Passed bias filter:                      341  (0.0190195); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.46u 0.24s 00:00:00.70 Elapsed: 00:00:00.38
# Mc/sec: 2678.74
//
Query:       EEA22798.1  [L=1462]
Description: MYB and HSA domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.7e-16   60.2   1.0    4.5e-16   58.8   0.2    2.2  2  Myb_DNA-bind_6   Myb-like DNA-binding domain
    1.3e-13   51.0   0.9    1.3e-13   51.0   0.9    4.3  4  HSA              HSA
    0.00024   21.2   1.8    0.00066   19.8   0.2    2.6  3  Myb_DNA-binding  Myb-like DNA-binding domain


Domain annotation for each model (and alignments):
>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.8   0.2   7.5e-20   4.5e-16       1      60 []     891     962 ..     891     962 .. 0.97
   2 ?   -2.6   0.0       1.2   6.9e+03       4      18 ..    1215    1229 ..    1215    1236 .. 0.89

  Alignments for each domain:
  == domain 1  score: 58.8 bits;  conditional E-value: 7.5e-20
  Myb_DNA-bind_6   1 WteeEdeiLlklvekygndWknIaealn..........rRtpkqcfdrwkn..kLrpkisrkkwskeedirL 60 
                     Wt  Ed++L++lv++y+++W++Ia++l+          rRtp++cf+rw    +L++++s++++++++++rL
      EEA22798.1 891 WTLNEDDELRRLVKDYSYNWSLIASCLSspslfssgaeRRTPWECFERWVGleGLPADMSKTQYFRAYHQRL 962
                     ***************************88********************998899**************998 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.2
  Myb_DNA-bind_6    4 eEdeiLlklvekygn 18  
                      +E+++Ll+  +++g+
      EEA22798.1 1215 QEQQRLLQSRQQQGQ 1229
                      699******999986 PP

>> HSA  HSA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.9   1.7         3   1.8e+04      56      69 ..     501     514 ..     499     515 .. 0.74
   2 !   51.0   0.9   2.3e-17   1.3e-13       3      50 ..     619     665 ..     616     681 .. 0.85
   3 ?   -0.7   1.1      0.32   1.9e+03       6      27 ..    1012    1033 ..    1010    1050 .. 0.75
   4 ?   -0.5   2.2      0.27   1.6e+03      55      68 ..    1075    1088 ..    1067    1099 .. 0.58

  Alignments for each domain:
  == domain 1  score: -3.9 bits;  conditional E-value: 3
                 XXXXXXXXXXXXXX CS
         HSA  56 qkriereekerlka 69 
                 +k+++ +eker k+
  EEA22798.1 501 VKQKKDREKERTKL 514
                 67888888888775 PP

  == domain 2  score: 51.0 bits;  conditional E-value: 2.3e-17
                 XXXXXXX--HHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHHHHH-- CS
         HSA   3 eperrqkthhdylLeeilwhakdfkeerkskrakakklaravakyhnn 50 
                 ep r q th+d+lL++++w+++df+eerk+k+a ak +a ++a y   
  EEA22798.1 619 EPLR-QGTHWDVLLDHMKWMRTDFREERKWKIAAAKSCAEWCAEYVHS 665
                 4555.***************************************9765 PP

  == domain 3  score: -0.7 bits;  conditional E-value: 0.32
                  XXXX--HHHHHHHTTHHHHHHH CS
         HSA    6 rrqkthhdylLeeilwhakdfk 27  
                  rr+ ++h +lL+++  +ak   
  EEA22798.1 1012 RRRASRHLALLDAMRKLAKKRE 1033
                  678999********99998744 PP

  == domain 4  score: -0.5 bits;  conditional E-value: 0.27
                  XXXXXXXXXXXXXX CS
         HSA   55 eqkriereekerlk 68  
                  eqk +er+e+ r +
  EEA22798.1 1075 EQKLQERQEQYRQQ 1088
                  55555555544433 PP

>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.0      0.64   3.9e+03       5      15 ..     315     325 ..     313     331 .. 0.88
   2 ?   -2.4   0.0      0.99   5.9e+03      19      34 ..     623     639 ..     619     640 .. 0.85
   3 !   19.8   0.2   1.1e-07   0.00066       2      42 ..     889     939 ..     888     942 .. 0.93

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.64
                      BHHHHHHHHHH CS
  Myb_DNA-binding   5 teeEdelLlea 15 
                      t++E+++++ea
       EEA22798.1 315 TPDEQLRFEEA 325
                      9*******998 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.99
                      HTTCHHHHHHHHT.SS- CS
  Myb_DNA-binding  19 hGnrWkkIaerlg.gRt 34 
                      +G  W+  ++++   Rt
       EEA22798.1 623 QGTHWDVLLDHMKwMRT 639
                      8999*******996687 PP

  == domain 3  score: 19.8 bits;  conditional E-value: 1.1e-07
                      SSSBHHHHHHHHHHHHHHTTCHHHHHHHHTS..........S-HHHHHHHH CS
  Myb_DNA-binding   2 gkWteeEdelLleavkkhGnrWkkIaerlgg..........Rtekqcrsrw 42 
                      ++Wt  Ed+ L ++vk +  +W++Ia+ l +          Rt+ +c +rw
       EEA22798.1 889 SQWTLNEDDELRRLVKDYSYNWSLIASCLSSpslfssgaerRTPWECFERW 939
                      68*************************99977799999999*********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1462 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1518  (0.0846673); expected 358.6 (0.02)
Passed bias filter:                      399  (0.0222544); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.98u 0.29s 00:00:01.27 Elapsed: 00:00:00.49
# Mc/sec: 8958.26
//
Query:       EEA22799.1  [L=492]
Description: 60S ribosome biogenesis protein Mak11, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-09   38.7   2.0       0.16   12.9   0.1    5.6  5  WD40      WD domain, G-beta repeat


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.3   0.0    0.0022        39       7      37 ..      88     128 ..      84     129 .. 0.72
   2 !   10.2   0.0   6.4e-05       1.1       4      36 ..     161     193 ..     158     195 .. 0.79
   3 !    3.7   0.0     0.007   1.3e+02      12      38 .]     229     256 ..     218     256 .. 0.81
   4 ?   -0.0   0.0      0.11   1.9e+03      19      37 ..     338     358 ..     322     359 .. 0.64
   5 !   12.9   0.1   8.9e-06      0.16      20      38 .]     408     425 ..     384     425 .. 0.71

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.0022
                 EESS.SSEEEEE.........EETTSSEEEEEETTSEEEEE CS
        WD40   7 ltGH.ssvtsla.........fspdgawlasGsdDgtvriW 37 
                 + +H s ++ la          +p  a la+G+ D  + ++
  EEA22799.1  88 FQAHtSAIRTLAlspptntdsSQPQTAILATGGSDERINLY 128
                 6799777*999966666655555555559**9779888776 PP

  == domain 2  score: 10.2 bits;  conditional E-value: 6.4e-05
                 EEEEESS.SSEEEEEEETTSSEEEEEETTSEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgawlasGsdDgtvri 36 
                 ++tl  H ss+t l f++ +++l s+ +D+t+ +
  EEA22799.1 161 IGTLLHHsSSITTLYFPSKSKLL-SAAEDNTISV 193
                 6778889788****888888887.5777***975 PP

  == domain 3  score: 3.7 bits;  conditional E-value: 0.007
                 SEEEEEEETTSSEEEE.E.ETTSEEEEEE CS
        WD40  12 svtslafspdgawlas.G.sdDgtvriWd 38 
                 +++++a++p+ ++++s G +  +  r+W+
  EEA22799.1 229 GINDFAVHPSMKLMISvGrG-ERCMRLWN 256
                 599**********8862555.*******8 PP

  == domain 4  score: -0.0 bits;  conditional E-value: 0.11
                 ETTSSE..EEEEETTSEEEEE CS
        WD40  19 spdgaw..lasGsdDgtvriW 37 
                 ++dg+   l+ ++dDg v ++
  EEA22799.1 338 DKDGSKeiLTVSTDDGRVLFY 358
                 33333364666778*999876 PP

  == domain 5  score: 12.9 bits;  conditional E-value: 8.9e-06
                 TTSSEEEEEETTSEEEEEE CS
        WD40  20 pdgawlasGsdDgtvriWd 38 
                     +++sGs Dg +riW+
  EEA22799.1 408 GTYLLVTSGS-DGIIRIWS 425
                 3333467889.*******5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (492 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       420  (0.0234257); expected 358.6 (0.02)
Passed bias filter:                      338  (0.0188521); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.25s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 3256.99
//
Query:       EEA22800.1  [L=519]
Description: translation initiation factor EF-2 gamma subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.3e-34  118.3   0.5    2.8e-34  117.2   0.5    1.6  1  eIF2_C       Initiation factor eIF2 gamma, C terminal
    3.5e-24   85.4   0.5    1.6e-23   83.2   0.5    2.0  1  GTP_EFTU     Elongation factor Tu GTP binding domain
    1.6e-11   44.4   0.1    3.8e-11   43.2   0.1    1.6  1  GTP_EFTU_D2  Elongation factor Tu domain 2
     0.0055   16.8   0.0      0.011   15.9   0.0    1.5  1  MMR_HSR1     50S ribosome-binding GTPase
      0.007   16.3   0.0      0.046   13.6   0.0    2.0  2  RsgA_GTPase  RsgA GTPase
  ------ inclusion threshold ------
      0.094   11.9   0.1       0.27   10.4   0.0    1.6  2  G-alpha      G-protein alpha subunit


Domain annotation for each model (and alignments):
>> eIF2_C  Initiation factor eIF2 gamma, C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.2   0.5   9.3e-38   2.8e-34       2      86 .]     420     508 ..     419     508 .. 0.95

  Alignments for each domain:
  == domain 1  score: 117.2 bits;  conditional E-value: 9.3e-38
                 EEEEEEEE-SBESSSSSC..CC..-----TTEEEEEEETTEEEEEEEEEEESSEEEEEEEEEEE-STTEEEEEEEEETTSEEEEEEEEE CS
      eIF2_C   2 eleieyellerlvgvkee..kk..veklkkkEvLmlniGsastggvvtsvkkdeakvkLkkPvcaekgekialsRrvekrWrLiGwGei 86 
                 ele++y+ll+rl+gvk+   k+  v+kl+k+EvLm+niGs++tg++v+ vk d ak+ L++P+c+e+gekia+sRr+ek+WrLiGw++i
  EEA22800.1 420 ELEVNYFLLRRLLGVKSAdgKQakVAKLSKNEVLMVNIGSTATGAKVVGVKADAAKLVLTNPACTEIGEKIAISRRIEKHWRLIGWANI 508
                 89**************99662256**************************************************************987 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   83.2   0.5   5.5e-27   1.6e-23       3     193 ..      91     294 ..      89     295 .. 0.86

  Alignments for each domain:
  == domain 1  score: 83.2 bits;  conditional E-value: 5.5e-27
                 EEEEEEEESTTSSHHHHHHHHHHHTTSSCHHHHHHHHHSTHCHSHHHHHHTSCSSCEEEEEE...................................TT CS
    GTP_EFTU   3 irnigiighvDhGKtTLtdrLlyktgaiskkgekaeeervlDtlkeErergiTiksaaisle...................................ke 66 
                 ++nig+ighv hGK+T++ ++ + + +  k               +E+er iTik   ++ +                                   + 
  EEA22800.1  91 TINIGTIGHVAHGKSTVVKAISEVHTIRFK---------------NEQERNITIKLGYANAKiykcdniecprptcyksyksekevdppceregctgTY 174
                 68******************9966666444...............566666666666666656666666677777778888888899***999887556 PP

                 CSSEEEEEEEESSSGGGHHHHHHHHHT-SEEEEEEETTTB.STHHHHHHHHHHHHTTTE.EEEEEESCGSTHHHHHHHHHHHHHHHHHHHHHHHHHHHT CS
    GTP_EFTU  67 tkkylinliDtPGHvdFskevirglrvlDgavlvvdaveG.vepqteevlrlalkegvp.iivfiNKmDrlkaelkeiveevkqklsrkeeklekygek 163
                    ++++++D+PGH   ++++  g++v+D a+l+++ +e  ++pqt e+l  +  ++++ ii++ NK+D +++e      +   k+      ++  +++
  EEA22800.1 175 RLLRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNETcPQPQTSEHLAAIEIMKLNhIIILQNKVDLMREEAALAHYQSILKF------IRGTVAD 267
                 77899*********************************9879*****************999999******998888877777788......9999999 PP

                 TTTTEEEEEEBTTTTBTHHHHHHHHHHHSH CS
    GTP_EFTU 164 gekevpvvfgSalkgegvktllealvellp 193
                 g+   p++++Sa  + +++++ e lv+++p
  EEA22800.1 268 GS---PIIPISAQLKYNIDAVNEHLVSHIP 294
                 97...***********************98 PP

>> GTP_EFTU_D2  Elongation factor Tu domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.2   0.1   1.3e-14   3.8e-11       1      65 [.     326     398 ..     326     408 .. 0.93

  Alignments for each domain:
  == domain 1  score: 43.2 bits;  conditional E-value: 1.3e-14
                  EEEEEEEEEESEEETTEEEEEEC.TCTTSEE........EEEEEEEEEEETEEESEEETTSEEEEEEEESSCCS CS
  GTP_EFTU_D2   1 GtvalgrvysGtlkkGdevrilg.ndtskke........ivtrissletfhededeavaganaGvivaikgled 65 
                  G+va+g++ +G+lk +de++i++   t ++e        i +++ sl+++h+d++ av+g+ +Gv+++i+++ +
   EEA22800.1 326 GGVAGGSILTGVLKLDDEIEIRPgIVT-RDEngkvqcrpIFSKVVSLYAEHNDLKFAVPGGLIGVGTRIDPTLC 398
                  89*********************9888.6667*************************************99876 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   3.6e-06     0.011       2      93 ..      94     219 ..      93     247 .. 0.69

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 3.6e-06
                 EEEEESTTSSHHHHHHHHHTS...TEEESSSTTSSSSEEEEEEEETT.EE....................................EEEEECGGCSSHH CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltge...kaivsdkpgtTrdinegrvklkg.ke....................................ielvDtpGliega 60 
                 ++ +G+   GKSt+++a+++    + + +++   T++  +++ k+ + ++                                    + +vD+pG  +  
  EEA22800.1  94 IGTIGHVAHGKSTVVKAISEVhtiRFKNEQERNITIKLGYANAKIYKcDNiecprptcyksyksekevdppceregctgtyrllrhVSFVDCPG-HD-- 189
                 889***************99654567777778888888888777443222556777777778888888888999999999999999********.43.. PP

                 HHHHHHHHHHHHHHC.TSEEEEEEETTTTCSHHH CS
    MMR_HSR1  61 seekglgkaflalee.adlillvvdaseeklkpl 93 
                      l  ++l+    +d++ll++  +e+  +p+
  EEA22800.1 190 ----ILMSTMLSGAAvMDAALLLIAGNETCPQPQ 219
                 ....567777765554688888886442222222 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0      0.25   7.5e+02     105     126 ..      97     118 ..      81     128 .. 0.75
   2 !   13.6   0.0   1.5e-05     0.046      13     101 ..     199     293 ..     176     297 .. 0.75

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.25
                  ECSTTSSHHHHHHHHCTT---- CS
  RsgA_GTPase 105 vGqSGvGKStLinallpelelk 126
                  +G+   GKSt+++a+ + ++++
   EEA22800.1  97 IGHVAHGKSTVVKAISEVHTIR 118
                  567778*******998765555 PP

  == domain 2  score: 13.6 bits;  conditional E-value: 1.5e-05
                  EES--EEEEEEESTTTT--HHHHHHHHHHHHHTT-EEEEEE.E-GGG--HHH......HHHHHHHHHHHTTSEEEE--TTTHTTHHHHHHHCTTSE CS
  RsgA_GTPase  13 vaNvdqllivvslkepelslnlldrfLvlaeekgiepvivl.nKiDlleeee......eleelkeelealgyevllvsaktkegleelkellkdkt 101
                  +a +d +l++++ + +++ + + +  L+++e  +++ +i+l nK+Dl+ ee       ++ ++   + a g +++ +sa+ k ++++++e+l +++
   EEA22800.1 199 AAVMDAALLLIAGN-ETCPQPQTSEHLAAIEIMKLNHIIILqNKVDLMREEAalahyqSILKFIRGTVADGSPIIPISAQLKYNIDAVNEHLVSHI 293
                  78899999999999.66667777889999**999966555549********966633333333444445588999999999999999999887665 PP

>> G-alpha  G-protein alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   8.9e-05      0.27      21      59 ..      89     128 ..      82     144 .. 0.84
   2 ?   -2.0   0.0      0.51   1.5e+03     271     287 ..     234     250 ..     223     281 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 8.9e-05
                 ..EEEEEEEESTTSSHHHHHHHHHHHCS----HHHHHC.C CS
     G-alpha  21 krevkllllGqseSGKsTilkqlkllykkgfseeelat.w 59 
                 + ++++  +G+   GKsT++k +  +++  f++e+ ++  
  EEA22800.1  89 QATINIGTIGHVAHGKSTVVKAISEVHTIRFKNEQERNiT 128
                 45799999**************************887634 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.51
                 EEEEEEE-HHHHHHHCC CS
     G-alpha 271 piiLflnKlDileeKlk 287
                 +ii++ nK+D+++e   
  EEA22800.1 234 HIIILQNKVDLMREEAA 250
                 6899999***9998764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (519 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       568  (0.0316805); expected 358.6 (0.02)
Passed bias filter:                      503  (0.0280551); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.57u 0.32s 00:00:00.88 Elapsed: 00:00:00.47
# Mc/sec: 3339.12
//
Query:       EEA22801.1  [L=194]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
        1.7    8.7   7.0        3.7    7.6   1.8    2.1  2  Peptidase_S49_N  Peptidase family S49 N-terminal


Domain annotation for each model (and alignments):
>> Peptidase_S49_N  Peptidase family S49 N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.3    0.0022        39      61      87 ..      89     117 ..      47     127 .. 0.51
   2 ?    7.6   1.8    0.0002       3.7      61      85 ..     157     181 ..     137     193 .. 0.66

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.0022
  Peptidase_S49_N  61 lldeeelka..aekkekkeekeekkaekk 87 
                      + +e+++++  ++k ek+ee+ee+ ++k+
       EEA22801.1  89 TATEAAARTpkKSKGEKQEEQEEQWENKE 117
                      22222222200222233333333333332 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0002
  Peptidase_S49_N  61 lldeeelkaaekkekkeekeekkae 85 
                      ++d++e+k+++k++k++ek+ + + 
       EEA22801.1 157 VIDKAERKRRKKERKQAEKKARAQL 181
                      5566666666666666666655554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (194 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1676  (0.0934798); expected 358.6 (0.02)
Passed bias filter:                      561  (0.0312901); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1302.46
//
Query:       EEA22802.1  [L=456]
Description: CaaX prenyl protease Ste24 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    7.3e-66  221.5   9.3    7.3e-66  221.5   9.3    1.8  2  Peptidase_M48_N  CAAX prenyl protease N-terminal, five membra
    8.6e-45  152.9   0.1    1.6e-44  152.0   0.1    1.4  1  Peptidase_M48    Peptidase family M48
  ------ inclusion threshold ------
       0.03   14.0   1.7      0.072   12.8   1.7    1.6  1  DUF4538          Domain of unknown function (DUF4538)
      0.037   13.2   3.3       0.21   10.7   3.3    1.9  1  Peptidase_M56    BlaR1 peptidase M56


Domain annotation for each model (and alignments):
>> Peptidase_M48_N  CAAX prenyl protease N-terminal, five membrane helices
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  221.5   9.3   1.6e-69   7.3e-66       1     182 []      42     226 ..      42     226 .. 0.97
   2 ?   -1.4   0.1      0.42   1.9e+03      36      79 ..     305     350 ..     285     362 .. 0.59

  Alignments for each domain:
  == domain 1  score: 221.5 bits;  conditional E-value: 1.6e-69
  Peptidase_M48_N   1 qlrklketkkvPeeladaitkekfdksraYgldksrfglvsslyslilllallllgllpflwklsgkl....lgl.daeseilqslvfllllsl 89 
                      q+r+l++tk +P+ l+++it++ f+ s+ Yg++k++fg++s++y+++++l+++++++lp++w+l+g +    +   ++++ei ++l+f++++ +
       EEA22802.1  42 QYRVLQHTK-PPKVLEGEITEKVFEDSQTYGRAKAKFGFFSGIYGQLQNLVFIYYDFLPKIWALTGVWlvryF-PsWSQGEIGHTLLFFFAFNI 133
                      99****997.*********************************************************996643.2599**************** PP

  Peptidase_M48_N  90 istlislPfslYstFviEekhGfnkqtlklfikdklkslllalviglpllaallwiiewggeyfylylwlfllvfslllmtiyPtlIaPLFnK 182
                      ++t++slP+s+YstFv+Eek+Gfnkqt++l+i+d+lk+++l+lv+g+p++aa+l+ii+++g+ f++ylw+f ++++++++tiyP++I P+FnK
       EEA22802.1 134 LTTILSLPISYYSTFVLEEKFGFNKQTVGLWITDMLKGQALGLVLGGPIMAAVLKIIQKTGNEFFYYLWIFSILVQVFAITIYPIVILPMFNK 226
                      ********************************************************************************************9 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.42
  Peptidase_M48_N  36 rfglvsslyslilllallllgllpflwklsgkl..lgldaeseilq 79 
                      ++g  ++l++ +++ +l ++ l+  + +  + +  +g+++e+ i+ 
       EEA22802.1 305 KLGHTTKLFGIAQAHMLYIFALFTAFVNNKSLFqsFGFHNEQPIMI 350
                      5555555666555555555554444333222222355555555555 PP

>> Peptidase_M48  Peptidase family M48
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  152.0   0.1   3.6e-48   1.6e-44       6     192 ..     234     432 ..     229     434 .. 0.96

  Alignments for each domain:
  == domain 1  score: 152.0 bits;  conditional E-value: 3.6e-48
                    HHHHHHHHHHHHTT-..-EEEEEEE-GGGT....-EEEEESSS-EEEEEEHHHH-SSB-HHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHH CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_M48   6 elkevveelakeaglpkpltkvyvvnspkr....NAFalgggknkrivltdgLlkqllseeelaaVlGHElGHikhrhsvvslivsllasillllg 97 
                     +k+ ve+la+++++  pl ++y ++++kr    NA++ g+ ++k+iv++d+L+ ++ ++ee+ aVl+HElGH+k +h+++ + +++  +++++ +
     EEA22802.1 234 LIKTGVEDLAQKLKF--PLHDIYSIDGSKRsahsNAYFFGFPWKKHIVIYDTLM-EKSEPEEVVAVLSHELGHWKLGHTTKLFGIAQAHMLYIFAL 326
                    58889**********..*************************************.***************************************** PP

                    HHHHTT-SHHHHHTT--S---HHHHHHHHHHTT.............HHHHHHHHHHHHHHHHTTT.HHHHHHHHHHHHHHTT--S---HHHHHHS- CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_M48  98 lallisraeedaagafldalavliglliillfl.............alSRkrEyqADeagvellkrakdlvraliklakdlerqdvsaslrsells 180
                    +++++++++++++++f+ +++++ig+l + + +              lSRk+E++AD+++++l++ +k l+++l kl+ +++++ ++++ ++ +++
     EEA22802.1 327 FTAFVNNKSLFQSFGFHNEQPIMIGFLLF-SDAlapmdavvkflmnILSRKFEFEADAFAANLGQ-SKLLAQSLLKLQIQNLSTMDADWMYASYHY 420
                    ***********************998754.4446*******************************.****************************** PP

                    SS--HHHHHHHH CS
                    xxxxxxxxxxxx RF
  Peptidase_M48 181 tHPplleRiqal 192
                    +HP+l+eR++al
     EEA22802.1 421 SHPILTERLAAL 432
                    **********98 PP

>> DUF4538  Domain of unknown function (DUF4538)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   1.7   1.6e-05     0.072       6      32 ..     200     226 ..     198     227 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.6e-05
     DUF4538   6 yvllvggvvgliglalYPiiiaPllhp 32 
                 y  +++ +v + ++++YPi+i P+ ++
  EEA22802.1 200 YLWIFSILVQVFAITIYPIVILPMFNK 226
                 56789999****************985 PP

>> Peptidase_M56  BlaR1 peptidase M56
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   3.3   4.7e-05      0.21      97     214 ..     190     311 ..     164     334 .. 0.73

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 4.7e-05
  Peptidase_M56  97 ewktilkillliWivgalillly.liaallvlkkrfvrklgklraeelkeaLkeakeemq..lkr..nikirlsssidsPavlgl.lkprIvlPad 186
                     +kt  ++  ++Wi+ +l+ ++  +i+ + +l   ++ kl++l++  +k  +++  ++ +  l     i  ++ s  ++  ++g  +k  Iv+ + 
     EEA22802.1 190 IQKTGNEFFYYLWIFSILVQVFAiTIYPIVILP--MFNKLSPLEPGLIKTGVEDLAQKLKfpLHDiySIDGSKRSAHSNAYFFGFpWKKHIVIYDT 283
                    555666788999999999955431445555555..799999999977777777777666633333113444666777888899954899******* PP

  Peptidase_M56 187 flkklsdeeleyillHElaHlkrkDllv 214
                    +++k + ee   +l HEl H k + +  
     EEA22802.1 284 LMEKSEPEEVVAVLSHELGHWKLGHTTK 311
                    ********************99876655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (456 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       546  (0.0304535); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.40
# Mc/sec: 3421.87
//
Query:       EEA22803.1  [L=382]
Description: CaaX prenyl protease Ste24 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.8e-66  222.1   9.3    4.8e-66  222.1   9.3    1.8  2  Peptidase_M48_N  CAAX prenyl protease N-terminal, five membra
    6.6e-30  104.3   0.0    1.3e-29  103.4   0.0    1.5  1  Peptidase_M48    Peptidase family M48
  ------ inclusion threshold ------
      0.023   14.4   1.7      0.058   13.1   1.7    1.6  1  DUF4538          Domain of unknown function (DUF4538)
      0.026   13.7   3.1      0.097   11.8   3.1    1.8  1  Peptidase_M56    BlaR1 peptidase M56


Domain annotation for each model (and alignments):
>> Peptidase_M48_N  CAAX prenyl protease N-terminal, five membrane helices
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  222.1   9.3   1.1e-69   4.8e-66       1     182 []      42     226 ..      42     226 .. 0.97
   2 ?   -1.1   0.1      0.33   1.5e+03      36      79 ..     305     350 ..     284     360 .. 0.58

  Alignments for each domain:
  == domain 1  score: 222.1 bits;  conditional E-value: 1.1e-69
  Peptidase_M48_N   1 qlrklketkkvPeeladaitkekfdksraYgldksrfglvsslyslilllallllgllpflwklsgkl....lgl.daeseilqslvfllllsl 89 
                      q+r+l++tk +P+ l+++it++ f+ s+ Yg++k++fg++s++y+++++l+++++++lp++w+l+g +    +   ++++ei ++l+f++++ +
       EEA22803.1  42 QYRVLQHTK-PPKVLEGEITEKVFEDSQTYGRAKAKFGFFSGIYGQLQNLVFIYYDFLPKIWALTGVWlvryF-PsWSQGEIGHTLLFFFAFNI 133
                      99****997.*********************************************************996643.2599**************** PP

  Peptidase_M48_N  90 istlislPfslYstFviEekhGfnkqtlklfikdklkslllalviglpllaallwiiewggeyfylylwlfllvfslllmtiyPtlIaPLFnK 182
                      ++t++slP+s+YstFv+Eek+Gfnkqt++l+i+d+lk+++l+lv+g+p++aa+l+ii+++g+ f++ylw+f ++++++++tiyP++I P+FnK
       EEA22803.1 134 LTTILSLPISYYSTFVLEEKFGFNKQTVGLWITDMLKGQALGLVLGGPIMAAVLKIIQKTGNEFFYYLWIFSILVQVFAITIYPIVILPMFNK 226
                      ********************************************************************************************9 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.33
  Peptidase_M48_N  36 rfglvsslyslilllallllgllpflwklsgkl..lgldaeseilq 79 
                      ++g  ++l++ +++ +l ++ l+  + +  + +  +g+++e+ i+ 
       EEA22803.1 305 KLGHTTKLFGIAQAHMLYIFALFTAFVNNKSLFqsFGFHNEQPIMI 350
                      5555556666666555555554444333222223355555555555 PP

>> Peptidase_M48  Peptidase family M48
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.4   0.0   2.8e-33   1.3e-29       6     140 ..     234     381 ..     229     382 .] 0.95

  Alignments for each domain:
  == domain 1  score: 103.4 bits;  conditional E-value: 2.8e-33
                    HHHHHHHHHHHHTT-..-EEEEEEE-GGGT....-EEEEESSS-EEEEEEHHHH-SSB-HHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHH CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  Peptidase_M48   6 elkevveelakeaglpkpltkvyvvnspkr....NAFalgggknkrivltdgLlkqllseeelaaVlGHElGHikhrhsvvslivsllasillllg 97 
                     +k+ ve+la+++++  pl ++y ++++kr    NA++ g+ ++k+iv++d+L+ ++ ++ee+ aVl+HElGH+k +h+++ + +++  +++++ +
     EEA22803.1 234 LIKTGVEDLAQKLKF--PLHDIYSIDGSKRsahsNAYFFGFPWKKHIVIYDTLM-EKSEPEEVVAVLSHELGHWKLGHTTKLFGIAQAHMLYIFAL 326
                    58889**********..*************************************.***************************************** PP

                    HHHHTT-SHHHHHTT--S---HHHHHHHHHHTT.............HHHHHHHHHH CS
                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.............xxxxxxxxxx RF
  Peptidase_M48  98 lallisraeedaagafldalavliglliillfl.............alSRkrEyqA 140
                    +++++++++++++++f+ +++++ig+l + + +              lSRk+E++A
     EEA22803.1 327 FTAFVNNKSLFQSFGFHNEQPIMIGFLLF-SDAlapmdavvkflmnILSRKFEFEA 381
                    ***********************998754.44469*******************99 PP

>> DUF4538  Domain of unknown function (DUF4538)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   1.7   1.3e-05     0.058       6      32 ..     200     226 ..     198     227 .. 0.89

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.3e-05
     DUF4538   6 yvllvggvvgliglalYPiiiaPllhp 32 
                 y  +++ +v + ++++YPi+i P+ ++
  EEA22803.1 200 YLWIFSILVQVFAITIYPIVILPMFNK 226
                 56789999****************985 PP

>> Peptidase_M56  BlaR1 peptidase M56
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   3.1   2.2e-05     0.097      93     214 ..     186     311 ..     133     334 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 2.2e-05
  Peptidase_M56  93 vkkvewktilkillliWivgalillly.liaallvlkkrfvrklgklraeelkeaLkeakeemq..lkr..nikirlsssidsPavlgl.lkprIv 182
                    v k+ +kt  ++  ++Wi+ +l+ ++  +i+ + +l   ++ kl++l++  +k  +++  ++ +  l     i  ++ s  ++  ++g  +k  Iv
     EEA22803.1 186 VLKIIQKTGNEFFYYLWIFSILVQVFAiTIYPIVILP--MFNKLSPLEPGLIKTGVEDLAQKLKfpLHDiySIDGSKRSAHSNAYFFGFpWKKHIV 279
                    5555566667888999***999955431455555555..799999999977777777777766633333113444666777888999954899*** PP

  Peptidase_M56 183 lPadflkklsdeeleyillHElaHlkrkDllv 214
                    + + +++k + ee   +l HEl H k + +  
     EEA22803.1 280 IYDTLMEKSEPEEVVAVLSHELGHWKLGHTTK 311
                    ************************99876655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (382 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       611  (0.0340789); expected 358.6 (0.02)
Passed bias filter:                      335  (0.0186848); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.47
# Mc/sec: 2430.60
//
Query:       EEA22804.1  [L=1050]
Description: zinc metalloprotease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.7e-18   65.0   0.0    8.7e-16   58.5   0.0    2.8  3  Peptidase_M16_C  Peptidase M16 inactive domain
    3.8e-05   23.7   0.0    0.00013   22.0   0.0    1.9  1  Peptidase_M16    Insulinase (Peptidase family M16)
  ------ inclusion threshold ------
        3.4    5.7   7.2        4.7    5.2   7.2    1.2  1  Sporozoite_P67   Sporozoite P67 surface antigen
        3.6    7.1  10.8        5.7    6.5  10.8    1.3  1  PPP4R2           PPP4R2


Domain annotation for each model (and alignments):
>> Peptidase_M16_C  Peptidase M16 inactive domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.5   0.0   1.9e-19   8.7e-16       1     174 [.     196     376 ..     196     384 .. 0.77
   2 ?   -2.4   0.0      0.92   4.1e+03       1      21 [.     432     452 ..     432     465 .. 0.84
   3 ?    3.2   0.0     0.017        76      92     164 ..     824     891 ..     763     911 .. 0.76

  Alignments for each domain:
  == domain 1  score: 58.5 bits;  conditional E-value: 1.9e-19
                      CH-HHHHHHHHHHHSSGGGEEEEEEESS-HHHHHHHHH....HHHTTSTHHSHCSGSCTSSSSSGGGSSEEEE...EEEESSSSSEEEEEEEEE CS
  Peptidase_M16_C   1 sltredlkefykkfYrpenmvlaivGdvdheelvklie....kyfgdlkaskappakptgepltpatlkkppv...vlkkldeeqahlslafeg 87 
                      slt+++++ef++++Y+p+n+ l+i G vdh++l+k ++      +  ++  +ap   p++e+  +++ k+++v     +++de++  +++ f+g
       EEA22804.1 196 SLTADRIREFHREMYQPKNLCLIITGEVDHDDLLKKLDafedTILDIIPRPDAPFKRPWVESERTPPIKESIVkevEFPEEDESSGEIEIRFLG 289
                      69**********************************99444333333444444666666666665555554441115555599*********** PP

                      ECTCTHTTHHHHHHHHHHHHSSTTSHHHHHHHTTTTSESEEEEEEEEES.SCEEEEEEEEEECTTHHHHHHHHHHHHHHHHHHTS-HH CS
  Peptidase_M16_C  88 pskendeddlalavlntlLgggmesrLytnlrekeglaysvsafndsyr.dsglfgisatadpenveevvevilkelrklkkegltee 174
                      p+ ++  +  al+v   +L g     L ++l eke+ a  v+++   +r d  + +  +++ +e++++v++ +++ l++  +  l+  
       EEA22804.1 290 PDCTDSVQGGALNVVLLYLAGSSATILENTLVEKEQVASAVYFSTE-DRpDIEIKFTLTSVATEKLQQVEKRFFEILHEAMERPLDMN 376
                      ********************************99999988888855.443555555555555569999*********99888776655 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 0.92
                      CH-HHHHHHHHHHHSSGGGEE CS
  Peptidase_M16_C   1 sltredlkefykkfYrpenmv 21 
                      ++t ++ kef++k+   +n v
       EEA22804.1 432 KWTEDQWKEFIRKWIADANHV 452
                      69999*********9988854 PP

  == domain 3  score: 3.2 bits;  conditional E-value: 0.017
                      THTTHHHHHHHHHHHHSSTTSHHHHHHHTTTTSESEEEEEEEEESSCEEEEEEEEEECTTHHHHHHHHHHHHH CS
  Peptidase_M16_C  92 ndeddlalavlntlLgggmesrLytnlrekeglaysvsafndsyrdsglfgisatadpenveevvevilkelr 164
                      +++   al v   ++ +  e++L  ++r   glay+ +++ +++   g   + ++  p+ ++++ +  +k ++
       EEA22804.1 824 DHPGLPALLVAIAYMNSV-EGPLWVAVR-GTGLAYGTNFGYNIDL--GTVNFDVYRSPN-AYKAFDSSKKIVE 891
                      666667777777777777.999******.***********99888..888888888877.4444433333333 PP

>> Peptidase_M16  Insulinase (Peptidase family M16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.0   0.0   2.9e-08   0.00013      29     107 ..      58     138 ..      53     166 .. 0.84

  Alignments for each domain:
  == domain 1  score: 22.0 bits;  conditional E-value: 2.9e-08
                    TTTTHHHHHHHHTTSBBSSSCH.HHHHHHHHHTTCEEEEEEESSEEEEEEEEEGGG.HHHHHHHHHHHHHSBTTSHHHHHH CS
  Peptidase_M16  29 dlnGlAHllehmafkgTkkyps.nklaeeleklGgslnAttsrentvYyvevlskd.lekaldvladvfkaplleesever 107
                    d +G  H leh+ f+g+ +y     l++ +++   + nA t +++t+Y+++++  + + ++l v  + ++ap+l++    +
     EEA22804.1  58 DDSGSPHTLEHLCFMGSRNYRYkGFLDKLATRFYSNTNAWTATDHTAYTLDTAGWAgFSDILPVYLEHVIAPTLTDAGCYT 138
                    557889**************99566667777777788**************9988889**************999876655 PP

>> Sporozoite_P67  Sporozoite P67 surface antigen
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.2   7.2     0.001       4.7      77     128 ..     982    1042 ..     970    1050 .] 0.56

  Alignments for each domain:
  == domain 1  score: 5.2 bits;  conditional E-value: 0.001
  Sporozoite_P67   77 ptpvseeiitrsfqep.....vsqeselqsdteined....dkGskedseedddeeeeedn 128 
                       +pv ee+i + f+       v+   ++++d  +  d    d+ +++d+eedd++++eed+
      EEA22804.1  982 CAPVLEETIKNGFESAgfkptVKPLKDFEDDYGLTVDgddeDDDDDDDEEEDDEDSDEEDD 1042
                      3599999999998887777777777777777655443000033333333444444444443 PP

>> PPP4R2  PPP4R2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5  10.8    0.0013       5.7     251     282 ..    1017    1048 ..     972    1050 .] 0.75

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0013
      PPP4R2  251 kdddeeddeedtdyveeeeddesedddeeeee 282 
                   d d+edd++d+d +e++ed+++eddd+++ee
  EEA22804.1 1017 VDGDDEDDDDDDDEEEDDEDSDEEDDDDDDEE 1048
                  45667777777777777777777777777666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1050 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1006  (0.0561102); expected 358.6 (0.02)
Passed bias filter:                      767  (0.0427799); expected 358.6 (0.02)
Passed Vit filter:                       113  (0.00630264); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.99u 0.33s 00:00:01.32 Elapsed: 00:00:00.56
# Mc/sec: 5656.41
//
Query:       EEA22805.1  [L=831]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.4e-09   35.8   0.3    8.9e-09   34.4   0.3    1.6  1  Zw10      Centromere/kinetochore Zw10
    1.8e-07   31.1   0.3    1.8e-07   31.1   0.3    1.9  2  Dsl1_C    Retrograde transport protein Dsl1 C terminal
  ------ inclusion threshold ------
      0.029   14.6   0.5         12    6.2   0.1    3.7  3  DUF948    Bacterial protein of unknown function (DUF948)


Domain annotation for each model (and alignments):
>> Zw10  Centromere/kinetochore Zw10
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.4   0.3   1.5e-12   8.9e-09      49     400 ..      69     397 ..      47     424 .. 0.81

  Alignments for each domain:
  == domain 1  score: 34.4 bits;  conditional E-value: 1.5e-12
        Zw10  49 eellerveslskeidalkkkveneieqd.....lkaaveelae....lkqqlkekevvlellealkkieealeelkealknkaflvaadlleelkslld 138
                 +  +++ ++l  +i+ + ++  n + q      l+a ve  a     ++++l  +e v ++le+++k++  +   ++a++  ++ +    le +++ l+
  EEA22805.1  69 DGWMSQARQLRADIERSRETARNIVAQHertqpLRARVEDAAAkvklINTELAFNEGVTHVLEEVQKFSAYISSGRKAVEGERINESITSLEAAQEFLQ 167
                 566788888888888888777766655411111445555555411115689999******************************************999 PP

        Zw10 139 lekvekafqlkilkalrkelsvlsenlqykLgeewdrlvvwklpsskelssaksflkvklklskeeseqkllsevleAlavlGeleeklklfgqvllkv 237
                 + +  k +++    +++   s l++++++ L   w r v+  +  sk        l+++ +  +e+s+   ls++l+ l+ l +l++   +f+q ll+ 
  EEA22805.1 168 SSNLSKYSNVA--SLVQGRSSSLRNDIVNLLLSCWTRQVR--V--SK------NELEIRPNKETEQSA---LSNILTSLSRLDILDSVNGSFQQGLLDD 251
                 99999988866..78889999******************9..3..33......458888777777777...**************************** PP

        Zw10 238 ilkplvlspslvav..vedqeeeitlrlessqetklekvepsevYskvlevlevllskLldvnvsselkkaslleilGeliweelseliikdcLvksiP 334
                 i++p+ +  s  ++  v+ +++++ +   ss       ++  ev  ++l v++ l++kL  +             ++ e+i ++ s ++ +  L  siP
  EEA22805.1 252 IIQPILMLDSPGKSrgVSVEDNGVYVGEPSS-------SSIPEVIDRLLLVFRYLQEKLPMSMS----------VSVAEAIIPKTSTMLNEHWLNRSIP 333
                 ****999877555545666666666554444.......44556779999****99999965443..........4567899****************** PP

        Zw10 335 enssklekyqevieqteeFeeaLkeleflsedesdLlkyardvnvhFaskkcqdvlvkArkLltse 400
                  + ++ + ++  + ++ eF  a+++l+   + +++L  + ++    + +++  d l + rk+l + 
  EEA22805.1 334 LDLEDIQGFESTLIRVTEFTGAIENLGW--KGQEELVSWVNQFPRLWLTRRRVDSLDQVRKILVQS 397
                 ***********999**********9998..67789999****************999999999776 PP

>> Dsl1_C  Retrograde transport protein Dsl1 C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.1       1.4   8.3e+03     162     188 ..     365     393 ..     364     396 .. 0.58
   2 !   31.1   0.3     3e-11   1.8e-07      76     187 ..     710     828 ..     644     831 .] 0.78

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 1.4
                 HHHHHHHHHH..S---HHHHHHHHHHHHH CS
      Dsl1_C 162 eeiiqWilll..fadtplrrdaiddirei 188
                 ee++ W+  +  +  t  r d++d++r+i
  EEA22805.1 365 EELVSWVNQFprLWLTRRRVDSLDQVRKI 393
                 78999987531122355555666666655 PP

  == domain 2  score: 31.1 bits;  conditional E-value: 3e-11
                 HHHHHHHHTTHHHHHHTSS---HHHH.......HHHHHHHHHHHHHT--GGGTT-HHHHHHHHHHHHHHHHHT--HHHHHHHHHTTGGGG.S-HHHHHH CS
      Dsl1_C  76 kllkflfndvvikeilkWkiisekns.......enlseliklllnateidslekeekyrelreklailakllplhlkdilemfynGdfyl.fateeiiq 166
                 +ll+ ++n ++i+ + + + ise +s       + ls l  + + + ++ +      y +   k++ l  +l+  l di  ++ +G+++l f++ee+i+
  EEA22805.1 710 SLLSSVINKMIID-VEDLSDISEAESqtlvtlcNKLSTLEDIFIPEPDVGATSMAAVYVRNWLKFQYLINILESSLADIKFLWTEGELHLeFSAEEVIE 807
                 4455555555543.4455667888871111111345566667777888889999999********************************99******** PP

                 HHHHHS---HHHHHHHHHHHH CS
      Dsl1_C 167 Willlfadtplrrdaiddire 187
                  i+ lfa+   rr +i +ir+
  EEA22805.1 808 LITALFAESDHRRRTISEIRR 828
                 *******************97 PP

>> DUF948  Bacterial protein of unknown function (DUF948)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   0.1     0.002        12      26      88 ..      52     117 ..      38     118 .. 0.82
   2 ?    2.9   0.1     0.022   1.3e+02      40      69 ..     388     417 ..     347     430 .. 0.69
   3 ?    0.6   0.0      0.11   6.8e+02      28      60 ..     674     706 ..     668     734 .. 0.57

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.002
      DUF948  26 ktldeaaatieelekqvdpilkevedllakvne...lledvneklekvdplteavadlgesvseln 88 
                 ++ de+++  +++ ++vd+ + ++++l a +++   ++ ++  + e+ +pl + v+d++++v+ +n
  EEA22805.1  52 QVEDEINSLSRDTVSDVDGWMSQARQLRADIERsreTARNIVAQHERTQPLRARVEDAAAKVKLIN 117
                 5668888888899999999999999997777665558888889***************99998766 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.022
      DUF948  40 kqvdpilkevedllakvnelledvneklek 69 
                 +qv++il ++++++++v+++ ++v   +++
  EEA22805.1 388 DQVRKILVQSKGTTKEVQRVEKEVVTSTDD 417
                 445555555555555555544444433333 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.11
      DUF948  28 ldeaaatieelekqvdpilkevedllakvnell 60 
                 l+e +++i+ + ++++++ ke + +l+++  l+
  EEA22805.1 674 LRECENAIDATVDRIRSVFKEWQPILSHSALLQ 706
                 445555555556666666666555555555433 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (831 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1039  (0.0579508); expected 358.6 (0.02)
Passed bias filter:                      579  (0.032294); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.80u 0.34s 00:00:01.14 Elapsed: 00:00:00.54
# Mc/sec: 4597.81
//
Query:       EEA22806.1  [L=485]
Description: microtubule associated protein (Ytm1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.4e-19   69.3  18.3    1.1e-06   29.2   0.6    6.6  6  WD40      WD domain, G-beta repeat
    4.5e-17   62.3   0.0    9.2e-17   61.3   0.0    1.5  1  NLE       NLE (NUC135) domain
    7.6e-05   21.5   5.0     0.0038   15.9   0.6    2.8  2  Nup160    Nucleoporin Nup120/160


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.4   0.3   0.00016      0.97      13      38 .]     114     151 ..     104     151 .. 0.61
   2 !   11.8   0.0   6.1e-05      0.36       9      38 .]     167     196 ..     160     196 .. 0.75
   3 !   17.0   0.0   1.4e-06    0.0083       3      38 .]     210     246 ..     208     246 .. 0.81
   4 !    8.2   0.3   0.00083         5       4      38 .]     285     321 ..     282     321 .. 0.84
   5 !   29.2   0.6   1.8e-10   1.1e-06       4      38 .]     372     408 ..     369     408 .. 0.93
   6 ?    0.5   0.1      0.22   1.3e+03      13      36 ..     450     472 ..     439     472 .. 0.71

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00016
                 EEEEE....EETTSSE............EEEEETTSEEEEEE CS
        WD40  13 vtsla....fspdgaw............lasGsdDgtvriWd 38 
                 v+s++    +    +             ++sGs+Dg +r+W+
  EEA22806.1 114 VSSVDvlssT----SVtgaqsvaagqerILSGSYDGLLRMWN 151
                 6666533332....22233344444445889**********8 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 6.1e-05
                 SS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   9 GH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 GH  s+ + +f +  ++ as++ D+tvr+W+
  EEA22806.1 167 GHtASIKAAKFISPTQL-ASAGLDRTVRVWK 196
                 88777888855555555.67777*******6 PP

  == domain 3  score: 17.0 bits;  conditional E-value: 1.4e-06
                 EEEEEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   3 clrtltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                 ++ +l GH s++ sl+++  ++ ++s+s D+tv +W+
  EEA22806.1 210 PQLELYGHkSGIESLSVHAPSNRMLSASADHTVGFWS 246
                 678899**777*****6666666678888****9995 PP

  == domain 4  score: 8.2 bits;  conditional E-value: 0.00083
                 EEEEESS.SSEEEEEEETTSSEE.EEEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgawl.asGsdDgtvriWd 38 
                 l  l+ H ++v++  f+   + +  s+s+D+++r Wd
  EEA22806.1 285 LALLSSHtGPVSAAIFDAKDSTVgYSASWDHSLRTWD 321
                 556789988898888999999987789*********9 PP

  == domain 5  score: 29.2 bits;  conditional E-value: 1.8e-10
                 EEEEESS.SSEEEEEEETTSSE.EEEEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtslafspdgaw.lasGsdDgtvriWd 38 
                 + tl+GH + v  la +p++++ l+sGs Dgt+riWd
  EEA22806.1 372 VMTLRGHtNAVVTLARDPHSSYgLISGSHDGTCRIWD 408
                 689****99999***********99**99*******9 PP

  == domain 6  score: 0.5 bits;  conditional E-value: 0.22
                 EEEEEEETTSSEEEEEETTSEEEE CS
        WD40  13 vtslafspdgawlasGsdDgtvri 36 
                 v +++++++   + s+++D+ + i
  EEA22806.1 450 VFGVCWDRSVGIV-SAGEDKRIQI 472
                 6788777777776.5666998865 PP

>> NLE  NLE (NUC135) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.3   0.0   1.5e-20   9.2e-17       1      65 []      16      80 ..      16      80 .. 0.94

  Alignments for each domain:
  == domain 1  score: 61.3 bits;  conditional E-value: 1.5e-20
         NLE  1 vqvrFvtkdedeslavpgtplsvPasltrkqLselvnkLlkeekpvpFdFlidgellrtsLeehL 65
                v+ +++t+d d  l+ + +p+ vP+ l+r+ Ls+lvn+Ll+++kp+p++Fl++g++lrts++e+L
  EEA22806.1 16 VRLHLTTRDGDIALPESTGPILVPTGLRRYALSTLVNNLLGNDKPIPLEFLVNGTYLRTSIDEYL 80
                56789***999999999************************6699******************97 PP

>> Nup160  Nucleoporin Nup120/160
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.6   0.3   0.00044       2.6     208     259 ..     114     164 ..     103     260 .. 0.76
   2 !   15.9   0.6   6.4e-07    0.0038     224     318 ..     298     418 ..     260     427 .. 0.73

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.00044
                 SS---TT-ECEEEEET.....TTTEEEEEETT-EEEEEETTTTEEEEEEE-- CS
      Nup160 208 rrksgasvalsldvavavveigqtylfalsrdgkLrvWnlltgkclatidll 259
                 ++  ++    s+  a++v+  gq  +++ s dg Lr+Wn ++++++ + d +
  EEA22806.1 114 VSSVDVLSSTSVTGAQSVAA-GQERILSGSYDGLLRMWNMSSQTTAVSPDAS 164
                 44444554445555555555.********************99988777666 PP

  == domain 2  score: 15.9 bits;  conditional E-value: 6.4e-07
                 ......TTTEEEEEETT-EEEEEETTTTEEEEEEE--............................-SSSTTS--SSEESEEESSSSEEEE......... CS
      Nup160 224 avvei.gqtylfalsrdgkLrvWnlltgkclatidll...........................rdeeaqdessskstldpaesslirvs......... 285
                 a+ ++ ++t+ +++s d+ Lr W+l t  ++ t++++                                              +s ++vs         
  EEA22806.1 298 AIFDAkDSTVGYSASWDHSLRTWDLVTSALVDTRSTShallslehlpelhllaagtsarhitliD----------------PRASATSVSvmtlrghtn 380
                 33333699999**********************99999999999999984444444443333321................333333333456666666 PP

                 ................E--GGG-EEEEEEEEEEE-...S CS
      Nup160 286 ......dggqsylvvtyspssggefkvwkvkkedtsvsl 318
                       ++ +s++ + +s s +g+  +w+v+++ t+ ++
  EEA22806.1 381 avvtlaRDPHSSYGL-ISGSHDGTCRIWDVRSTKTDKEG 418
                 6666669*******9.99999***********9997764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (485 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       295  (0.0164538); expected 358.6 (0.02)
Passed bias filter:                      262  (0.0146132); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.51u 0.24s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 3504.90
//
Query:       EEA22807.1  [L=119]
Description: 40S ribosomal protein S13 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.1e-20   73.4   0.6    3.5e-18   66.2   0.6    2.0  1  Ribosomal_S13  Ribosomal protein S13/S18


Domain annotation for each model (and alignments):
>> Ribosomal_S13  Ribosomal protein S13/S18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.2   0.6     2e-22   3.5e-18       2     126 ..       4     106 ..       3     108 .. 0.97

  Alignments for each domain:
  == domain 1  score: 66.2 bits;  conditional E-value: 2e-22
  Ribosomal_S13   2 ilgtdidgkkkveialtaikGiGrrkakiilkkadvdedkrigelteeeiekieeivenkaqykipnwinrqkdikdGkdshvvendlrrklredi 97 
                    ilg++ ++++ v+ +l++  GiG++ ++ +l++  +  +++ig+l+++++  i+  +++                      +++endlrr++ +di
     EEA22807.1   4 ILGVNFPERNLVKKSLQTFFGIGNNVSSRLLARFHIHPTAKIGDLQNQQVLDITAALSE----------------------MKIENDLRRQILDDI 77 
                    7899*****************************************************99......................89************* PP

  Ribosomal_S13  98 eRlkkirsyrGlRHkrGlkvRGQrTkttg 126
                    +Rl++ ++yrG RH  Gl+vRGQ+T++  
     EEA22807.1  78 KRLRDTGTYRGRRHALGLPVRGQNTRSQI 106
                    **************************975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (119 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       498  (0.0277762); expected 358.6 (0.02)
Passed bias filter:                      382  (0.0213063); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.29s 00:00:00.72 Elapsed: 00:00:00.46
# Mc/sec: 773.44
//
Query:       EEA22808.1  [L=271]
Description: peptidyl-prolyl cis-trans isomerase (CypB), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.4e-48  164.4   0.2    3.2e-48  164.0   0.2    1.1  1  Pro_isomerase  Cyclophilin type peptidyl-prolyl cis-trans iso
  ------ inclusion threshold ------
        0.8    9.4   3.8        1.2    8.8   2.7    1.9  2  DUF3149        Protein of unknown function (DUF3149)


Domain annotation for each model (and alignments):
>> Pro_isomerase  Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  164.0   0.2   3.5e-52   3.2e-48       2     156 ..      39     193 ..      38     195 .. 0.89

  Alignments for each domain:
  == domain 1  score: 164.0 bits;  conditional E-value: 3.5e-52
  Pro_isomerase   2 vdietss..kGrivieLfadkaPktvenFlklvkeg....fYdgttFhRvikgfmvqgGdptgktsageqe.kkggesiraipdEitsklkh.krG 89 
                    +die ++  +Griv+ L+++++P t+enF++l+ +g     Y+g++FhRvik+fm+qgGd+t+++   ++  +    + ++++dE+ +kl+h k+G
     EEA22808.1  39 FDIEQDGqsLGRIVFGLYGKTVPLTAENFRALA-TGekgfGYEGSSFHRVIKNFMIQGGDFTNHDG--TGGkSI---YGNKFADEN-FKLRHtKKG 127
                    5676655669***********************.5668899*******************999855..322133...3369*****.88899899* PP

  Pro_isomerase  90 alamartgkepnsagsqFfItlkeaphldgkytvFGkVveGmdvvekiekvetde.erpkknvkivsa 156
                    +l+ma++g  ++++gsqFfIt+  +++ldg+++vFG+V+eG+dvvekie+++t+  +rp ++v+iv+ 
     EEA22808.1 128 LLSMANAG--KDTNGSQFFITTVITSWLDGRHVVFGEVLEGYDVVEKIENTPTKPgDRPLSAVTIVRS 193
                    *******8..6******************************************************975 PP

>> DUF3149  Protein of unknown function (DUF3149)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0      0.37   3.4e+03      10      15 ..     127     132 ..     124     132 .. 0.82
   2 ?    8.8   2.7   0.00014       1.2       7      28 ..     240     261 ..     239     262 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 0.37
     DUF3149  10 GLlSli 15 
                 GLlS++
  EEA22808.1 127 GLLSMA 132
                 9***95 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.00014
     DUF3149   7 sdvGLlSliVIvftigmgaffi 28 
                 s +G  Sl+VI+++++++++++
  EEA22808.1 240 SVTGFSSLAVIAVIVLVVLYMA 261
                 6689***************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (271 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       523  (0.0291706); expected 358.6 (0.02)
Passed bias filter:                      400  (0.0223102); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.27s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1849.17
//
Query:       EEA22809.1  [L=206]
Description: peptidyl-prolyl cis-trans isomerase (CypB), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.1e-48  165.4   0.2    1.4e-48  165.2   0.2    1.0  1  Pro_isomerase  Cyclophilin type peptidyl-prolyl cis-trans iso


Domain annotation for each model (and alignments):
>> Pro_isomerase  Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  165.2   0.2   7.7e-53   1.4e-48       2     156 ..      39     193 ..      38     195 .. 0.89

  Alignments for each domain:
  == domain 1  score: 165.2 bits;  conditional E-value: 7.7e-53
  Pro_isomerase   2 vdietss..kGrivieLfadkaPktvenFlklvkeg....fYdgttFhRvikgfmvqgGdptgktsageqe.kkggesiraipdEitsklkh.krG 89 
                    +die ++  +Griv+ L+++++P t+enF++l+ +g     Y+g++FhRvik+fm+qgGd+t+++   ++  +    + ++++dE+ +kl+h k+G
     EEA22809.1  39 FDIEQDGqsLGRIVFGLYGKTVPLTAENFRALA-TGekgfGYEGSSFHRVIKNFMIQGGDFTNHDG--TGGkSI---YGNKFADEN-FKLRHtKKG 127
                    5676655669***********************.5668899*******************999855..322133...3369*****.88899899* PP

  Pro_isomerase  90 alamartgkepnsagsqFfItlkeaphldgkytvFGkVveGmdvvekiekvetde.erpkknvkivsa 156
                    +l+ma++g  ++++gsqFfIt+  +++ldg+++vFG+V+eG+dvvekie+++t+  +rp ++v+iv+ 
     EEA22809.1 128 LLSMANAG--KDTNGSQFFITTVITSWLDGRHVVFGEVLEGYDVVEKIENTPTKPgDRPLSAVTIVRS 193
                    *******8..6******************************************************975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (206 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       353  (0.0196888); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.25s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 1494.13
//
Query:       EEA22810.1  [L=692]
Description: ATP dependent RNA helicase (Dbp1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    4.3e-49  166.7   0.0    1.1e-48  165.3   0.0    1.6  2  DEAD           DEAD/DEAH box helicase
    1.5e-31  109.1   0.0    3.9e-31  107.7   0.0    1.7  2  Helicase_C     Helicase conserved C-terminal domain
     0.0022   18.0   0.0     0.0039   17.2   0.0    1.4  1  ResIII         Type III restriction enzyme, res subunit
  ------ inclusion threshold ------
      0.046   13.1   0.1      0.079   12.3   0.1    1.2  1  CMS1           U3-containing 90S pre-ribosomal complex subuni
       0.17   11.1   0.0       0.27   10.4   0.0    1.2  1  ERCC3_RAD25_C  ERCC3/RAD25/XPB C-terminal helicase


Domain annotation for each model (and alignments):
>> DEAD  DEAD/DEAH box helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  165.3   0.0   3.1e-52   1.1e-48       1     175 [.     220     408 ..     220     409 .. 0.95
   2 ?   -2.0   0.0      0.71   2.5e+03      76     105 ..     483     516 ..     447     522 .. 0.58

  Alignments for each domain:
  == domain 1  score: 165.3 bits;  conditional E-value: 3.1e-52
                 -HHHHHHHHHHHTTCEEEEEESTTSSHHHHHHHHHHHHHHHS.................TTSTS-EEEEEESSHHHHHHHHHHHHHHTTTSTSEEEEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD   1 tdiQaeaiplilgggdvlvaaeTGsGKTlaflipvlqivyet.................kgktgpkalivePtreLaeqtlnnlkkfkkyidlrvllii 82 
                 t++Q+ +ip++++g+d++++a+TGsGKT+ fl+p+l++ ++t                 ++k  p  li++PtreL+ q++++++kf     +r ++++
  EEA22810.1 220 TPVQKYSIPIVMNGRDLMACAQTGSGKTGGFLFPILSQAFQTgpsaapapaaggnfygrQRKAYPTSLILAPTRELVSQIYDEARKFAYRSWVRPCVVY 318
                 79*************************************9*9************9999999999*************************9889****** PP

                 TTSSHHHHHHHHHTTCSEEEEEHHHHHHHHHCTSSHCTTEEEEEEETHHHHHHTTTHHHHHHHHHHSHHHCTTSTTTSEEEEEESSBSHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        DEAD  83 ggvaardqlskldngvdivvgtpgrlddllstgklnlsqvrflVlDEadrlldqgfsdfinrilnqlpqitcdgklqrqvivlSATlpkdvkk 175
                 gg +  +ql+++++g+d++v+tpgrl+dl+++g+++l ++++lVlDEadr+ld+gf+++i+ri++  +    +  ++rq++++SAT+p+d++ 
  EEA22810.1 319 GGADIGSQLRQIERGCDLLVATPGRLVDLIERGRISLTNIKYLVLDEADRMLDMGFEPQIRRIVEGED--MPQV-NDRQTLMFSATFPRDIQM 408
                 **************************************************************998772..3333.4678**********9986 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 0.71
                 SEEEEEETTSSHHHHHHHH...H.TTCSEEEEEH CS
                 xxxxxxxxxxxxxxxxxxx...x.xxxxxxxxxx RF
        DEAD  76 lrvlliiggvaardqlskl...d.ngvdivvgtp 105
                   + +i g+ ++r+  ++l   + +++ i+v+t 
  EEA22810.1 483 FPATAIHGDRTQRERERALemfRnARCPILVATA 516
                 3445666666666666666333324499999885 PP

>> Helicase_C  Helicase conserved C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.0       3.2   1.2e+04      19      72 ..     286     339 ..     279     341 .. 0.56
   2 !  107.7   0.0   1.1e-34   3.9e-31       1     111 []     443     553 ..     443     553 .. 0.94

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 3.2
                 EEEEESSHHHHHH....HHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEE CS
  Helicase_C  19 ilifvntidrlek....vklllekkgikvavlhgelpqnereeileqfnkgesdvLia 72 
                 +li ++t++ +++    ++ +  ++ ++ +v++g     ++++ +e+     +d+L+a
  EEA22810.1 286 SLILAPTRELVSQiydeARKFAYRSWVRPCVVYGGADIGSQLRQIERG----CDLLVA 339
                 677777777443233344555444456777777766666666555554....555555 PP

  == domain 2  score: 107.7 bits;  conditional E-value: 1.1e-34
                 HHHHHHHHHHHHTTTTSEEEEEESSHHHHHH.HHHHHHHTTSTEEEESTTSTHHHHHHHHHHHHTTSSSEEEESGGGTSSSTSTTESEEEESSSSSSHH CS
  Helicase_C   1 dkleallellkleeeggkilifvntidrlek.vklllekkgikvavlhgelpqnereeileqfnkgesdvLiatdvaerGidipkvnlVinfdlprnvt 98 
                 dk + ll++l+++ ++g +lifv+t++++++ +++l  ++++ ++++hg+ +q+ere++le f++ ++ +L+at va+rG+dip+v++V+n+dlp++++
  EEA22810.1 443 DKRSVLLDILHTHGSTGLTLIFVETKRMADSlCDFL-INQNFPATAIHGDRTQRERERALEMFRNARCPILVATAVAARGLDIPNVTHVVNYDLPTDID 540
                 577899999999*****************9866666.5667********************************************************** PP

                 HHHHHHTTSSSTT CS
  Helicase_C  99 syiqriGRtgRag 111
                 +y++riGRtgRag
  EEA22810.1 541 DYVHRIGRTGRAG 553
                 ***********97 PP

>> ResIII  Type III restriction enzyme, res subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.2   0.0   1.1e-06    0.0039      27     170 ..     236     403 ..     207     404 .. 0.84

  Alignments for each domain:
  == domain 1  score: 17.2 bits;  conditional E-value: 1.1e-06
                 EEEEESTTSTHHHHH.HHHHHHH-S........................-EEEEESSHHHHHHHHHHGGGGTGG....GEEEESSS-B--........- CS
      ResIII  27 glikmaTGtGKTlva.aklierllkkgkee...................kflflvprkslleqtleefkkflseaykeigkkvsgdkkka.kekdstnk 104
                 ++  + TG+GKT    + +  + ++ g+                       l+l+p+++l++q ++e +kf+     + + ++ g    +  ++ +  +
  EEA22810.1 236 LMACAQTGSGKTGGFlFPILSQAFQTGPSAapapaaggnfygrqrkaypTSLILAPTRELVSQIYDEARKFAYRSWVRPCVVYGGADIGSqLRQIERGC 334
                 556678******9887999999999999889****************************************99887664444333333334455689** PP

                 SEEEEEHHHHHHTH........HHHTTT-SEEEEETGGGTTS....TTTHHH.....HHT---SEEEEEESS-S CS
      ResIII 105 kilvttiqsldadseeeeeeseellrdrfdviiiDEaHrlgak...kswrei.....lekfkeavllglTATpe 170
                 ++lv+t  +l   +     e+ + + +++++++ DEa r+ ++    ++r+i     + ++++   l ++AT++
  EEA22810.1 335 DLLVATPGRLVDLI-----ERGRISLTNIKYLVLDEADRMLDMgfePQIRRIvegedMPQVNDRQTLMFSATFP 403
                 **************.....9999999****************9776599998676555555779999*****97 PP

>> CMS1  U3-containing 90S pre-ribosomal complex subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.1   2.2e-05     0.079     182     209 ..     338     365 ..     330     370 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 2.2e-05
        CMS1 182 vGtpgRildLleeeslsvdeLkrivlDa 209
                 v tpgR++dL+e + +s+ ++k++vlD 
  EEA22810.1 338 VATPGRLVDLIERGRISLTNIKYLVLDE 365
                 78************************96 PP

>> ERCC3_RAD25_C  ERCC3/RAD25/XPB C-terminal helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   7.4e-05      0.27      80     131 ..     483     533 ..     473     563 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 7.4e-05
  ERCC3_RAD25_C  80 lkkpyiyGetseaerlkilqkfkknpkvntiflskvgDtsiDlPeanvliqi 131
                    +  + i+G+ +++er + l+ f++  ++  ++   v+   +D+P+ + ++  
     EEA22810.1 483 FPATAIHGDRTQRERERALEMFRNA-RCPILVATAVAARGLDIPNVTHVVNY 533
                    556779****************976.89999999***********9988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (692 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       348  (0.0194099); expected 358.6 (0.02)
Passed bias filter:                      236  (0.013163); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.65u 0.27s 00:00:00.92 Elapsed: 00:00:00.47
# Mc/sec: 4433.29
//
Query:       EEA22811.1  [L=1367]
Description: INO80 chromatin remodeling complex (Ies1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1367 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       524  (0.0292264); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.85u 0.34s 00:00:01.19 Elapsed: 00:00:00.51
# Mc/sec: 8061.70
//
Query:       EEA22812.1  [L=350]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.5e-67  226.1   1.7    4.5e-67  225.8   1.7    1.1  1  INSIG     Insulin-induced protein (INSIG)


Domain annotation for each model (and alignments):
>> INSIG  Insulin-induced protein (INSIG)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  225.8   1.7   2.5e-71   4.5e-67       2     211 ..     130     334 ..     129     335 .. 0.94

  Alignments for each domain:
  == domain 1  score: 225.8 bits;  conditional E-value: 2.5e-71
       INSIG   2 rallLfvlGvvygvlvtrlheerkl.lvkke.ksssswrylvfwGlagvalGlllpwlDrlweekfaeeeeeeeeekeeekaaseadwalvvrsigafv 98 
                 ++ lLf++Gv+yg+++ +lhe++++ +vk e  +++s  yl+ wG+agva++++lpwlD+l +++        +++++++ +++++  +l++rsigafv
  EEA22812.1 130 KTSLLFICGVTYGTIIAHLHENNWIaPVKLEyIDRNSYVYLLAWGIAGVAFAFVLPWLDKLGDND--------TADQNKDVENKQSTVTLAIRSIGAFV 220
                 789**********************8777779****************************66444........3456778899999************* PP

       INSIG  99 GiafAirklpwastlqvsltlalvnpfLWyliDrskpGfllsaavgllgtavllglnpdlvpaPsaaasaaaaaaaaeealgg.asqeslevaiwllsv 196
                 GiafA+r+lpw+s +q s+tlalvnp+LWyliDr+++Gf+ls++v+++g+ + lgl+p+l+p+ s++     ++ + e  ++g +sq++++va+wl+sv
  EEA22812.1 221 GIAFAMRRLPWESATQESVTLALVNPLLWYLIDRTRTGFWLSTVVAIVGMGITLGLHPELIPSSSSTVGLGLRNWRLEYDIEGgISQDATAVAVWLASV 319
                 *************************************************************9988888999999999******9*************** PP

       INSIG 197 LFcscvcfGniGRrL 211
                 ++++cvcfGniGR+L
  EEA22812.1 320 FYSACVCFGNIGRQL 334
                 **************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (350 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       396  (0.0220871); expected 358.6 (0.02)
Passed bias filter:                      312  (0.017402); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.49
# Mc/sec: 2153.39
//
Query:       EEA22813.1  [L=594]
Description: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.7e-93  311.0   0.0    1.8e-92  310.0   0.0    1.5  1  AICARFT_IMPCHas  AICARFT/IMPCHase bienzyme
    2.9e-25   88.3   0.0    5.4e-25   87.4   0.0    1.5  1  MGS              MGS-like domain


Domain annotation for each model (and alignments):
>> AICARFT_IMPCHas  AICARFT/IMPCHase bienzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  310.0   0.0     2e-96   1.8e-92       1     296 []     134     461 ..     134     461 .. 0.91

  Alignments for each domain:
  == domain 1  score: 310.0 bits;  conditional E-value: 2e-96
                      HHHTTTT-EEE-SGGGHHHHHHHHHCT.B-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSE...EEEEEEEEESSSSSTTS-E.EEEE-TTST CS
  AICARFT_IMPCHas   1 AAKNhksVtvvvdpadYeevleelkkgevsletrkklaakaFahtaaYDaaiaeylskqlpetlklslekkqkLrYGeNphQka.alyeeeeee 93 
                      AAKNh++Vt+++dp+dY e+l+el++ge+s++trk +a+kaF+hta+YDaai++y++kq++     ++ +  +LrYG+NphQk+ a+y    + 
       EEA22813.1 134 AAKNHARVTILSDPKDYPEFLKELEAGEISEQTRKLYALKAFEHTADYDAAISAYFRKQYA----GDGVQYLSLRYGTNPHQKPaAAYV---TG 220
                      9*******************************************************99986....5788889***********967775...45 PP

                      THHH-EEEESS---HHHHHHHHHHHHHHCTS..E....EEEEEETTEEEEEEE.....................ESSHHHHHHHHHCCSHHHHT CS
  AICARFT_IMPCHas  94 glakaeqlqGkelsynNllDadaalelvkef..a....avaivKHanpcGvAv.....................getlaeAyekAlaaDpvSaF 160
                      g   ++ l G +++y+NllD  +a+ lvke+  a    a+a++KH++p+G+A+                     ++ la+Ay++A+ aD++S+F
       EEA22813.1 221 GKLPFKVLGG-SPGYVNLLDSLNAWPLVKELkqAlglpAAASFKHVSPAGAAIgvplnekerkvyfvddiagieSSPLAQAYARARGADRMSSF 313
                      6678988988.******************997625566888*******************************987779**************** PP

                      TEEEEECCEE-HHHHHHHTTS-ECEEEECEE-CCHHHCCTTS..SS-EEEE-SS-......EEEEETTEEEEEE--G..TTCCCS.EEECSC.. CS
  AICARFT_IMPCHas 161 GgiialnrevdaetaeeikkefleviiApsfeeealeilkkk..knlrvlelkee......elrsvsgglLvqerdeakieeeel.kvvtkk.. 243
                      G+iial+++vd+ ta++i++e+++++iAp++e+ealeilkkk  +++ vl+++e+      e+r++ g  L q r++ +++++++ +++t k  
       EEA22813.1 314 GDIIALSDKVDVPTAKIISREVSDGVIAPDYEPEALEILKKKkgGKYLVLQIDETytppatETRTLYGVQLEQGRNDFTVTSKTFsSIITPKdt 407
                      ***************************************7764779******995556777999997777******999999977677777533 PP

                      .---HHHHHHHHHHHHHCCCS-SS-EEEEETTEEEEEE-SSSSHHHHHHHHHHH CS
  AICARFT_IMPCHas 244 .kpteeeledllfawkvvkhvkSNaivlakdgqtvgiGaGqmsRvdsarlAvek 296
                       +  e++l+dl++a++++k+++SN++++a +gq++g+GaGq+sR++++rlA++k
       EEA22813.1 408 kTLPESALRDLTVATIALKYTQSNSVCYALNGQIIGLGAGQQSRIHCTRLAGDK 461
                      3567999********************************************987 PP

>> MGS  MGS-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.4   0.0     6e-29   5.4e-25       1      95 []      15     129 ..      15     129 .. 0.98

  Alignments for each domain:
  == domain 1  score: 87.4 bits;  conditional E-value: 6e-29
                 THHHHHHHHHHTTCEEEEEHHHHHHHHHTT--EEECCCCHSTGSGGTHCH.................HHHHHHHTTSCC...EEEEE--THHHHHHCHH CS
         MGS   1 glvelakklkelgfellATgGTakllkeagipvtevvektgegerlggrv.................eildaikngeid...lvintlypfkatvakdg 79 
                 gl++lak l++ ++++lA+gGTak+++eag pv++v+ +t+ +e+lggrv                 ++++++++++i+   +v+++lypfk tvak++
  EEA22813.1  15 GLLDLAKGLAQQNVRILASGGTAKMIREAGFPVEDVSAITNAPEMLGGRVktlhpavhggilarnieSDEKDLAEQKINkvdYVVCNLYPFKDTVAKPN 113
                 689****************************************************************999999999999999***************** PP

                 HHHHHHHHHTTSHEES CS
         MGS  80 ykirraaenidIplpt 95 
                 ++i++a+e++dI+++t
  EEA22813.1 114 VTIAEAVEEVDIGGVT 129
                 **************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (594 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       434  (0.0242066); expected 358.6 (0.02)
Passed bias filter:                      403  (0.0224776); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.24s 00:00:00.84 Elapsed: 00:00:00.43
# Mc/sec: 4167.21
//
Query:       EEA22814.1  [L=593]
Description: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.7e-93  311.0   0.0    1.8e-92  310.0   0.0    1.5  1  AICARFT_IMPCHas  AICARFT/IMPCHase bienzyme
    2.9e-25   88.3   0.0    5.3e-25   87.4   0.0    1.5  1  MGS              MGS-like domain


Domain annotation for each model (and alignments):
>> AICARFT_IMPCHas  AICARFT/IMPCHase bienzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  310.0   0.0     2e-96   1.8e-92       1     296 []     133     460 ..     133     460 .. 0.91

  Alignments for each domain:
  == domain 1  score: 310.0 bits;  conditional E-value: 2e-96
                      HHHTTTT-EEE-SGGGHHHHHHHHHCT.B-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSE...EEEEEEEEESSSSSTTS-E.EEEE-TTST CS
  AICARFT_IMPCHas   1 AAKNhksVtvvvdpadYeevleelkkgevsletrkklaakaFahtaaYDaaiaeylskqlpetlklslekkqkLrYGeNphQka.alyeeeeee 93 
                      AAKNh++Vt+++dp+dY e+l+el++ge+s++trk +a+kaF+hta+YDaai++y++kq++     ++ +  +LrYG+NphQk+ a+y    + 
       EEA22814.1 133 AAKNHARVTILSDPKDYPEFLKELEAGEISEQTRKLYALKAFEHTADYDAAISAYFRKQYA----GDGVQYLSLRYGTNPHQKPaAAYV---TG 219
                      9*******************************************************99986....5788889***********967775...45 PP

                      THHH-EEEESS---HHHHHHHHHHHHHHCTS..E....EEEEEETTEEEEEEE.....................ESSHHHHHHHHHCCSHHHHT CS
  AICARFT_IMPCHas  94 glakaeqlqGkelsynNllDadaalelvkef..a....avaivKHanpcGvAv.....................getlaeAyekAlaaDpvSaF 160
                      g   ++ l G +++y+NllD  +a+ lvke+  a    a+a++KH++p+G+A+                     ++ la+Ay++A+ aD++S+F
       EEA22814.1 220 GKLPFKVLGG-SPGYVNLLDSLNAWPLVKELkqAlglpAAASFKHVSPAGAAIgvplnekerkvyfvddiagieSSPLAQAYARARGADRMSSF 312
                      6678988988.******************997625566888*******************************987779**************** PP

                      TEEEEECCEE-HHHHHHHTTS-ECEEEECEE-CCHHHCCTTS..SS-EEEE-SS-......EEEEETTEEEEEE--G..TTCCCS.EEECSC.. CS
  AICARFT_IMPCHas 161 GgiialnrevdaetaeeikkefleviiApsfeeealeilkkk..knlrvlelkee......elrsvsgglLvqerdeakieeeel.kvvtkk.. 243
                      G+iial+++vd+ ta++i++e+++++iAp++e+ealeilkkk  +++ vl+++e+      e+r++ g  L q r++ +++++++ +++t k  
       EEA22814.1 313 GDIIALSDKVDVPTAKIISREVSDGVIAPDYEPEALEILKKKkgGKYLVLQIDETytppatETRTLYGVQLEQGRNDFTVTSKTFsSIITPKdt 406
                      ***************************************7764779******995556777999997777******999999977677777533 PP

                      .---HHHHHHHHHHHHHCCCS-SS-EEEEETTEEEEEE-SSSSHHHHHHHHHHH CS
  AICARFT_IMPCHas 244 .kpteeeledllfawkvvkhvkSNaivlakdgqtvgiGaGqmsRvdsarlAvek 296
                       +  e++l+dl++a++++k+++SN++++a +gq++g+GaGq+sR++++rlA++k
       EEA22814.1 407 kTLPESALRDLTVATIALKYTQSNSVCYALNGQIIGLGAGQQSRIHCTRLAGDK 460
                      3567999********************************************987 PP

>> MGS  MGS-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   87.4   0.0     6e-29   5.3e-25       1      95 []      14     128 ..      14     128 .. 0.98

  Alignments for each domain:
  == domain 1  score: 87.4 bits;  conditional E-value: 6e-29
                 THHHHHHHHHHTTCEEEEEHHHHHHHHHTT--EEECCCCHSTGSGGTHCH.................HHHHHHHTTSCC...EEEEE--THHHHHHCHH CS
         MGS   1 glvelakklkelgfellATgGTakllkeagipvtevvektgegerlggrv.................eildaikngeid...lvintlypfkatvakdg 79 
                 gl++lak l++ ++++lA+gGTak+++eag pv++v+ +t+ +e+lggrv                 ++++++++++i+   +v+++lypfk tvak++
  EEA22814.1  14 GLLDLAKGLAQQNVRILASGGTAKMIREAGFPVEDVSAITNAPEMLGGRVktlhpavhggilarnieSDEKDLAEQKINkvdYVVCNLYPFKDTVAKPN 112
                 689****************************************************************999999999999999***************** PP

                 HHHHHHHHHTTSHEES CS
         MGS  80 ykirraaenidIplpt 95 
                 ++i++a+e++dI+++t
  EEA22814.1 113 VTIAEAVEEVDIGGVT 128
                 **************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (593 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       432  (0.024095); expected 358.6 (0.02)
Passed bias filter:                      400  (0.0223102); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.28s 00:00:00.92 Elapsed: 00:00:00.48
# Mc/sec: 3739.12
//
Query:       EEA22815.1  [L=307]
Description: hypothetical protein PMAA_094230 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    8.7e-05   22.5   0.4    0.00053   19.9   0.4    2.1  1  DUF3425     Domain of unknown function (DUF3425)
  ------ inclusion threshold ------
      0.091   11.9   0.0       0.15   11.2   0.0    1.3  1  Avian_gp85  Avian retrovirus envelope protein, gp85
       0.12   11.3   0.0       0.16   10.8   0.0    1.1  1  DUF5588     Family of unknown function (DUF5588)


Domain annotation for each model (and alignments):
>> DUF3425  Domain of unknown function (DUF3425)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.9   0.4   8.9e-08   0.00053      18     118 ..     194     298 ..     188     304 .. 0.75

  Alignments for each domain:
  == domain 1  score: 19.9 bits;  conditional E-value: 8.9e-08
     DUF3425  18 lpenlrPtelQlriaHpveidvlpwpelRdrllrafqeeeidedeffrdvvstlivWsieeeelet............aeissaelsagdvtdlegWel 104
                 lp+++rP +       +++ d++ wp++R++l+++++   + ++ +f+   ++++    +                  +++++ + +     d++ +++
  EEA22815.1 194 LPPWFRPRKYHAYSSESIVNDYFAWPRFRQKLITSNNP-PLTNRFWFYFTRNVQFECDLS-----PahtididpdtgkYRLTTVFRDV--TDDIHRYTM 284
                 9*********************************6666.455555555553333333222.....13335567777777777777777..67999**** PP

     DUF3425 105 kesFfrkYpylvdg 118
                  ++Ff+ Yp+ +++
  EEA22815.1 285 GSEFFEAYPECFED 298
                 *********98877 PP

>> Avian_gp85  Avian retrovirus envelope protein, gp85
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   2.6e-05      0.15      69     103 ..     269     303 ..     261     306 .. 0.91

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 2.6e-05
  Avian_gp85  69 tepftvvtadrhnlfmgseycgaygyrfwnmyncs 103
                 t  f  vt d h   mgse+  ay   f ++y c+
  EEA22815.1 269 TTVFRDVTDDIHRYTMGSEFFEAYPECFEDVYACA 303
                 677999****************************7 PP

>> DUF5588  Family of unknown function (DUF5588)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   2.7e-05      0.16     153     213 ..      14      74 ..      10     104 .. 0.88

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 2.7e-05
     DUF5588 153 slhpfnpwswgklaeaylslgpalsasiassqkqnsstssdkavksssvhsgkdcllclpe 213
                 s  p++pws g++  a       l   ++ s+++n+   + k+v+s     ++ cl  lp 
  EEA22815.1  14 STTPLKPWSSGRVLSAAQRERKRLMNRASQSRRRNNLKNTLKTVESRLFQIERRCLAYLPP 74 
                 567**********************99999**************************99985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (307 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       610  (0.0340231); expected 358.6 (0.02)
Passed bias filter:                      530  (0.029561); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.22s 00:00:00.75 Elapsed: 00:00:00.42
# Mc/sec: 2205.74
//
Query:       EEA22816.1  [L=505]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.4e-21   74.3   0.0    1.6e-20   73.2   0.0    1.4  2  AATase    Alcohol acetyltransferase


Domain annotation for each model (and alignments):
>> AATase  Alcohol acetyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0     0.087   1.6e+03       5      54 ..      16      72 ..      14      74 .. 0.64
   2 !   73.2   0.0     9e-25   1.6e-20     117     477 ..     104     471 ..      89     487 .. 0.77

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 0.087
      AATase  5 lEkyfvvrnrqklysnfsvyaeln....kevdk...eqLalalrslilknpiLaani 54
                +Ek f vr+ +  y+ +++ + +     ++ d       ++a+++ i ++p L a+i
  EEA22816.1 16 IEKRFTVRHALGWYRALIIAGLYTvdkaSAFDThsiASYIPAMKRCIKNHPFLSATI 72
                677777777777777777776664222233333111356789999999999999887 PP

  == domain 2  score: 73.2 bits;  conditional E-value: 9e-25
      AATase 117 ekvdeelnellselvipvgd......pkkPlwrlivlpsaddkk..kwkkfv.fitdHllfDGisgvnffkdlleelekikqdnalkkdevildyekdv 206
                 +k +e+ +el+++++++ +d      ++ P w+++vlp  d+ +  + + ++ ++  H+  D+ s+  f++  l+ l+    dn  + + +i+++    
  EEA22816.1 104 YKSEEDELELFKKVILETHDqlwpdaERIPPWKIVVLPFPDQADstQKRVYIiYAFSHTHGDAKSALAFHRSFLQGLQTQAADNN-EDQSLIYKP---- 197
                 344556666666666665542222226889*******977766644445556699*************************99999.566666655.... PP

      AATase 207 eelekLPkpieekvdyrpsllalpklllvsfiaskl.nfkks.........eekpltkehsavqksn.kshqiilkispeevkkirakikknvhgkatl 294
                   +++LP p+ee  + + s+++l   +l   + +++ ++             ++  t e+  ++k n     +il ++ + ++k+ + ++++      l
  EEA22816.1 198 -PSSPLPLPLEEACNLKISWSFLLAPVLAQYMPNIVcRLL-GiqaggsqlsVDRGYTGEITSYDKDNfRTASQILVVKQDMLAKVLTVCRSQ---CSKL 291
                 .34599**************99887777766655431222.23567998876666666777776654255678999****************...777* PP

      AATase 295 TpflqavffvalyklgklfkeknsevsidvaipvntRrylpedeevrdsykYgtvvggseFsyl.issldieedskeklwelveeyhkrlseslsngke 392
                 T  l+  + +al +l  l+ e  +++  ++ +  + R+ +p  ++    +  g +v +  +      + + + ++ e++w+ v   ++rl + ++n   
  EEA22816.1 292 TGLLNRLIVYALSEL--LPPETANGFIGQIVV--DLRSQIPAYAD---GMTMGNFVSA-AYDTSsRTTPNPNSKYDETFWDAVRGTTTRLAA-TANTLD 381
                 **************6..899999988877665..67******999...5556777877.454430344556667889*************98.666666 PP

      AATase 393 lkglgtlildlllkyvnidkllkkkilktkrstaevsNlGlfsq..........eeeskykvkdliFsqaagslknafslnvistnsgGlnlsls 477
                  + +g     ll    n      +++ k++ s  e+sN+G f             ++++++++  +Fsq+a  l  ++ + v+s + g + ++l 
  EEA22816.1 382 DQPIG-----LLKYLSNFRAWFLSHLGKKRDSSYEISNIGVFDPtlsnindmatTTSQPWTIERTVFSQPANVLASPLNFQVVSMKGGDMVITLN 471
                 66777.....467778************************99766677787887899*****************************999988775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (505 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       456  (0.0254337); expected 358.6 (0.02)
Passed bias filter:                      428  (0.0238719); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.27s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 3487.40
//
Query:       EEA22817.1  [L=1675]
Description: clathrin heavy chain [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   1.7e-198  650.4  44.4    1.5e-32  112.5   0.4    7.5  7  Clathrin         Region in Clathrin and VPS
      3e-37  125.1   0.5    8.1e-07   29.1   0.0    6.7  6  Clathrin_propel  Clathrin propeller repeat
    9.4e-33  111.9   1.5    3.5e-32  110.1   0.3    2.8  2  Clathrin_H_link  Clathrin-H-link
    0.00077   19.5   3.6       0.38   11.1   0.0    5.2  3  TPR_8            Tetratricopeptide repeat
     0.0054   15.8   8.4       0.04   13.0   0.2    4.1  4  Coatomer_WDAD    Coatomer WD associated region
     0.0055   16.6   5.6         26    5.1   0.0    6.5  6  TPR_7            Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.014   15.3   0.1      0.075   13.0   0.0    2.3  2  VapB_antitoxin   Bacterial antitoxin of type II TA system, Va
      0.017   15.2   4.2        7.8    6.9   0.1    5.8  5  TPR_2            Tetratricopeptide repeat
      0.085   12.7   3.4        6.6    6.7   0.0    4.7  4  TPR_1            Tetratricopeptide repeat
       0.15   12.0   6.2        6.6    6.6   0.0    4.8  4  Utp13            Utp13 specific WD40 associated domain
       0.15   12.9  12.0         49    5.1   0.0    8.0  6  TPR_14           Tetratricopeptide repeat
        0.2   11.9  17.2        8.6    6.7   0.0    7.0  6  Vps39_1          Vacuolar sorting protein 39 domain 1
       0.21   11.9   6.7         10    6.4   0.0    4.9  4  DUF1400          Alpha/beta hydrolase of unknown function (DU
        1.1    9.2   3.3       0.83    9.6   0.1    2.6  2  Rop              Rop protein
        2.3    8.5   8.6         38    4.7   0.1    5.3  5  TPR_12           Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> Clathrin  Region in Clathrin and VPS
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.3   0.7   1.8e-24   2.1e-21       7     142 ..     547     682 ..     541     683 .. 0.92
   2 !   75.9   0.3   2.3e-24   2.8e-21       3     142 ..     692     830 ..     690     831 .. 0.93
   3 !  100.0   1.7   8.5e-32     1e-28       7     133 ..     844     966 ..     841     974 .. 0.96
   4 !  112.5   0.4   1.2e-35   1.5e-32       2     139 ..     985    1124 ..     984    1128 .. 0.97
   5 !   97.9   1.2   3.9e-31   4.7e-28       2     142 ..    1134    1272 ..    1133    1273 .. 0.96
   6 !  104.3   1.4   3.9e-33   4.7e-30       1     141 [.    1279    1422 ..    1279    1424 .. 0.97
   7 !  111.9   0.5   1.8e-35   2.2e-32       1     143 []    1428    1570 ..    1428    1570 .. 0.97

  Alignments for each domain:
  == domain 1  score: 76.3 bits;  conditional E-value: 1.8e-24
                 TS-CCCCHHHHHCTT-HHHHCHHHCCHHHCHTS--HHHHHHHHHHHHHTT-HHHHHHTTS..S---S-TTHHHHHHHT-SSHHHHHHHHHTTXTHSSHS CS
    Clathrin   7 pidlsrvvklfeeaglleelleyLekvlkedskenpalqtallelyakyddpqeleeflk..knnnydlekvaklcekadlyeeavilykkinefkkai 103
                  +dl+rvv+ f +++++++++++L ++lk +++e+ +lqt+lle+++ + + q+++++l   ++++yd++++a+lce+a+l+++a++   +   +k+  
  EEA22817.1 547 LVDLDRVVDVFLSQNMIQQATSFLLDALKDNKPEQGHLQTRLLEMNLINAP-QVADAILGneMFTHYDKARIAQLCENAGLIQRALENTEDPAVIKR-- 642
                 689***********************************************6.*********************************************.. PP

                 SXSSSSHCSCHHH..HTTTTTXXSHHHHHHHHHHHSSXSHH CS
    Clathrin 104 sllkklkdfddai..eyaakvsnpelwekllealldkkpfe 142
                 +l+k+ + ++ ++  +y++++s+++++e l e+l+++ +++
  EEA22817.1 643 NLVKT-DKLNPEWliKYFGRLSQEQALEGLDEMLNSNIRQN 682
                 76666.555555558*********************99987 PP

  == domain 2  score: 75.9 bits;  conditional E-value: 2.3e-24
                 CCCTTS-CCCCHHHHHCTT-HHHHCHHHCCHHHCHTS--HHHHHHHHHHHHHTT-HHHHHHTTSS---S-TTHHHHHHHT-SSHHHHHHHHHT..TXTH CS
    Clathrin   3 eltdpidlsrvvklfeeaglleelleyLekvlkedskenpalqtallelyakyddpqeleeflkknnnydlekvaklcekadlyeeavilykk..inef 99 
                 +++d + ++r+++lfe++   e l++yL ++++    e+p+++ +++e++  +++++e+e++++++n+y++ekv +++++a+l+e+++++  +  +n++
  EEA22817.1 692 KFSDLLGNNRLIDLFEKYRTAEGLYYYLGSIVN--LSEDPEVHFKYIEAATAMGQLTEVERICRESNYYNPEKVKNFLKEANLTEQLPLIIVCdrFNFI 788
                 67899999************************5..4478**************************************************888888**** PP

                 SSHSSXSSSSHCSCHHHHTTTTTXXSHHHHHHHHHHHSSXSHH CS
    Clathrin 100 kkaisllkklkdfddaieyaakvsnpelwekllealldkkpfe 142
                 ++++  + + ++  + ie+++++ np   + +++ lld +++e
  EEA22817.1 789 HDLVL-YLYRNQQYKSIEVYVQRVNPSRSPAVIGGLLDVDCDE 830
                 **886.888899999**********************999986 PP

  == domain 3  score: 100.0 bits;  conditional E-value: 8.5e-32
                 TS-CCCCHHHHHCTT-HHHHCHHHCCHHHCHTS--HHHHHHHHHHHHHTT-HHHHHHTTSS---S-TTHHHHHHHT-SSHHHHHHHHHTTXTHSSHSSX CS
    Clathrin   7 pidlsrvvklfeeaglleelleyLekvlkedskenpalqtallelyakyddpqeleeflkknnnydlekvaklcekadlyeeavilykkinefkkaisl 105
                 +i+++++v+++e++++l++ll++Le+ l++++++ +a+++al+++y+++++  ++e+flk+n+ yd+  v+k+cek+d+  +a+i y+k +++ ++i++
  EEA22817.1 844 QIPIDELVQEVESRNRLKLLLPFLESTLATGNQQ-QAVYNALAKIYIDSNN--NPEKFLKENDMYDTLIVGKYCEKRDPN-LAYIAYSKGQNDLELINI 938
                 689*************************999777.***************7..***************************.****************** PP

                 SSSSHCSCHHHHTTTTTXXSHHHHHHHH CS
    Clathrin 106 lkklkdfddaieyaakvsnpelweklle 133
                 ++++ +++ +++y+  + +pe+w+++l+
  EEA22817.1 939 TNENAMYRAQARYLLDRADPEIWSFVLN 966
                 **************************97 PP

  == domain 4  score: 112.5 bits;  conditional E-value: 1.2e-35
                  CCCCTTS-CCCCHHHHHCTT-HHHHCHHHCCHHHCHTS..--HHHHHHHHHHHHHTT-HHHHHHTTSS---S-TTHHHHHHHT-SSHHHHHHHHHTT CS
    Clathrin    2 ieltdpidlsrvvklfeeaglleelleyLekvlkedsk..enpalqtallelyakyddpqeleeflkknnnydlekvaklcekadlyeeavilykki 96  
                  +e+t+p+ +s  vk f +a+l+ el+e+Lek+++e s+  +n++lq++l+ ++ak d+ ++l +++ ++n+++++++a++c   +lyeea+++ykk+
  EEA22817.1  985 PESTEPDKVSVAVKSFLDADLPAELIELLEKIILEPSPfsDNSSLQNLLMLTAAKADK-SRLIDYIHRLNEFNADEIAQMCISVGLYEEAFEIYKKV 1080
                  689*********************************99*******************9.************************************** PP

                  XTHSSHSSX.SSSSHCSCHHHHTTTTTXXSHHHHHHHHHHHSSX CS
    Clathrin   97 nefkkaisl.lkklkdfddaieyaakvsnpelwekllealldkk 139 
                  n+++ a+++ +++  ++d+a eya++v+ pe+w+k+++a+ld  
  EEA22817.1 1081 NNHTAATDVlVENIVSIDRAQEYAERVELPEVWSKVAKAQLDGL 1124
                  ********88******************************9975 PP

  == domain 5  score: 97.9 bits;  conditional E-value: 3.9e-31
                  CCCCTTS-CCCCHHHHHCTT-HHHHCHHHCCHHHCHTS--HHHHHHHHHHHHHTT-HHHHHHTTSS---S-TTHHHHHHHT-SSHHHHHHHHHTTXT CS
    Clathrin    2 ieltdpidlsrvvklfeeaglleelleyLekvlkedskenpalqtallelyakyddpqeleeflkknnnydlekvaklcekadlyeeavilykkine 98  
                  i+++d++++++v++ + +ag+ e l +yL++++k+    +pa++tal+ + a+ d++ ele+fl+ +n  d+e  ++++ +++ +e a+i y+ i++
  EEA22817.1 1134 IKANDASNYNEVIETATHAGKDEDLVKYLRMARKTL--REPAIDTALAFCFARLDQLAELEDFLRATNVADVEASGDKAYEEGFHEAAKIFYTSISN 1228
                  7899*****************************755..55********************************************************* PP

                  HSSHSSXSSSSHCSCHHHHTTTTTXXSHHHHHHHHHHHSSXSHH CS
    Clathrin   99 fkkaisllkklkdfddaieyaakvsnpelwekllealldkkpfe 142 
                  ++k++++l +l+d++ a+e a+k+++ ++w+++ ea+++kk+f+
  EEA22817.1 1229 WAKLATTLVHLEDYQAAVECARKANSVKVWKQVSEACINKKEFR 1272
                  ****************************************9986 PP

  == domain 6  score: 104.3 bits;  conditional E-value: 3.9e-33
                  CCCCCTTS-CCCCHHHHHCTT-HHHHCHHHCCHHHCHTS--HHHHHHHHHHHHHTT-HHHHHHTTSS---.S-TTHHHHHHHT-SSHHHHHHHHHTT CS
    Clathrin    1 lieltdpidlsrvvklfeeaglleelleyLekvlkedskenpalqtallelyakyddpqeleeflkknnn.ydlekvaklcekadlyeeavilykki 96  
                  l+++ ++++l+ +vk+++++g+++el+++Le++l + +++++ ++t+l +++ ky++ ++++e+lk +++ ++++k+++ +e+a+l+ e+v+ly ++
  EEA22817.1 1279 LNLIVHAEELNDLVKQYQRNGYFDELISLLEAGL-GLERAHMGMFTELGIALSKYHP-DRVMEHLKLFWSrINIPKMIRATEEANLWPELVFLYCHY 1373
                  68899*****************************.999******************6.*************************************** PP

                  XTHSSHSS.X.SSSSHCSCHHH..HTTTTTXXSHHHHHHHHHHHSSXSH CS
    Clathrin   97 nefkkais.l.lkklkdfddai..eyaakvsnpelwekllealldkkpf 141 
                  +e+++a+  +  +  +++++    ++++kv n e+++++l+++l+++p 
  EEA22817.1 1374 DEWDNAALaMmERAAEAWEHHSfkDIIVKVANLEIYYRALNFYLQEQPL 1422
                  ********966**********************************9986 PP

  == domain 7  score: 111.9 bits;  conditional E-value: 1.8e-35
                  CCCCCTTS-CCCCHHHHHCTT-HHHHCHHHCCHHHCHTS--HHHHHHHHHHHHHTT-HHHHHHTTSS---S-TTHHHHHHHT-SSHHHHHH...HHH CS
    Clathrin    1 lieltdpidlsrvvklfeeaglleelleyLekvlkedskenpalqtallelyakyddpqeleeflkknnnydlekvaklcekadlyeeavi...lyk 94  
                  l+ lt +id+srvv++f++ +++++++++L +v+    ++ +a+++a+++l+++++d++ l++++++++nyd+ ++a+++ek+dl+ ++ i   +y+
  EEA22817.1 1428 LQVLTARIDVSRVVRIFQSSDNIPLIKPFLLSVQ---GQNKRAVNDAINDLLIEEEDYKTLRDSVDNYDNYDPVELAQRLEKHDLVFFRQIaanIYR 1521
                  678999****************************...57889******************************************************* PP

                  TTXTHSSHSSXSSSSHCSCHHHHTTTTTXXSHHHHHHHHHHHSSXSHHH CS
    Clathrin   95 kinefkkaisllkklkdfddaieyaakvsnpelwekllealldkkpfel 143 
                  k+++++k+i l+k++k+f+daie+aa + ++e++e+ll++++d++ +e+
  EEA22817.1 1522 KNKRWEKSIALSKQDKLFKDAIETAAMSGKSEVVEELLRYFVDIGSREC 1570
                  *******************************************998775 PP

>> Clathrin_propel  Clathrin propeller repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.1     3e-06    0.0036       3      36 ..      20      56 ..      18      57 .. 0.93
   2 ?    6.2   0.0     0.012        15       6      37 .]      66      96 ..      63      96 .. 0.92
   3 !   29.1   0.0   6.8e-10   8.1e-07       2      35 ..     153     189 ..     152     191 .. 0.96
   4 !   16.5   0.0   6.7e-06     0.008       2      37 .]     203     238 ..     202     238 .. 0.95
   5 !   27.1   0.0   2.7e-09   3.3e-06       6      37 .]     260     291 ..     256     291 .. 0.95
   6 !   20.5   0.0   3.4e-07   0.00041       1      37 []     299     333 ..     299     333 .. 0.97

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 3e-06
                     TCEEEECCCEEEEECCEEEEEE...CETEEEEEEEET CS
  Clathrin_propel  3 nsqiinfptatneswlfiiain...gtkkGqvqlysv 36
                     ++  i+f ++t es+++i+++     t+k qv ++++
       EEA22817.1 20 EPSSIGFNSCTLESDHYICVRQkvnETDKPQVIIINL 56
                     6779*********************99********98 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.012
                     EEECCCEEEEECCEEEEEE..CETEEEEEEEETT CS
  Clathrin_propel  6 iinfptatneswlfiiain..gtkkGqvqlysve 37
                     +in+++a+++ +  +ia++   ++   +q++++e
       EEA22817.1 66 PINADSAIMHWSRNVIALKaqSRT---IQIFDLE 96
                     79******************8888...9999997 PP

  == domain 3  score: 29.1 bits;  conditional E-value: 6.8e-10
                      TTCEEEECCCEEEEECCEEEEEE...CETEEEEEEEE CS
  Clathrin_propel   2 ansqiinfptatneswlfiiain...gtkkGqvqlys 35 
                       ++qiin++++++ +w ++++i+   g+++G +qlys
       EEA22817.1 153 SGCQIINYRVNDEDKWSVVVGISqqqGRVVGSMQLYS 189
                      689*********************************8 PP

  == domain 4  score: 16.5 bits;  conditional E-value: 6.7e-06
                      TTCEEEECCCEEEEECCEEEEEECETEEEEEEEETT CS
  Clathrin_propel   2 ansqiinfptatneswlfiiaingtkkGqvqlysve 37 
                      a ++ i +++++ e+ lf +a++++++ ++q+ +++
       EEA22817.1 203 AAFASIRVEGSPLEHKLFTFAVRTQTGAKLQIAEID 238
                      889*****************************9997 PP

  == domain 5  score: 27.1 bits;  conditional E-value: 2.7e-09
                      EEECCCEEEEECCEEEEEECETEEEEEEEETT CS
  Clathrin_propel   6 iinfptatneswlfiiaingtkkGqvqlysve 37 
                       ++fp+a+++s ++ i++  tk+G+++ly++e
       EEA22817.1 260 TNDFPVAMQVSKKYDIVYLVTKYGFIHLYDLE 291
                      79****************************98 PP

  == domain 6  score: 20.5 bits;  conditional E-value: 3.4e-07
                      CTTCEEEECCCEEEEECCEEEEEECETEEEEEEEETT CS
  Clathrin_propel   1 nansqiinfptatneswlfiiaingtkkGqvqlysve 37 
                      n++s +++f+ta++  + +++++n  +kGqv+++s++
       EEA22817.1 299 NRISSETIFTTAPDSESTGLVGVN--RKGQVLSVSLD 333
                      79999*******************..*********97 PP

>> Clathrin_H_link  Clathrin-H-link
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.1   0.3   2.9e-35   3.5e-32       1      66 []     359     424 ..     359     424 .. 0.99
   2 ?   -2.5   0.0       4.2     5e+03      16      32 ..    1236    1252 ..    1234    1254 .. 0.79

  Alignments for each domain:
  == domain 1  score: 110.1 bits;  conditional E-value: 2.9e-35
  Clathrin_H_link   1 gLpGaddlyvqqFeqllaqgnykeAakvAaespqgiLRtpetIqrfkqvpaqpgqlspllqYFgtL 66 
                      gLpGad+ly+qqF++llaqgny+eAak+Aa+sp+g+LRtpetI+rfk++p+  +q+s++lqYFg+L
       EEA22817.1 359 GLPGADHLYQQQFDNLLAQGNYSEAAKIAANSPRGFLRTPETINRFKNAPQGGQQMSVILQYFGML 424
                      8****************************************************************8 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 4.2
  Clathrin_H_link   16 llaqgnykeAakvAaes 32  
                       l+  ++y++A+++A ++
       EEA22817.1 1236 LVHLEDYQAAVECARKA 1252
                       566789*******9776 PP

>> TPR_8  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.81   9.7e+02       3      16 ..     880     893 ..     879     897 .. 0.85
   2 ?    3.8   0.1     0.068        81       7      27 ..    1060    1080 ..    1059    1081 .. 0.90
   3 !   11.1   0.0   0.00032      0.38       3      29 ..    1228    1254 ..    1226    1256 .. 0.91

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.81
                 HHHHHHHHHHHTT- CS
       TPR_8   3 ayynlgsiylklgd 16 
                 +y+ l++iy++ ++
  EEA22817.1 880 VYNALAKIYIDSNN 893
                 79*******98776 PP

  == domain 2  score: 3.8 bits;  conditional E-value: 0.068
                  HHHHHHHTT-HHHHHHHHHHH CS
       TPR_8    7 lgsiylklgdyeeAkeyyeka 27  
                  +++ +++ g yeeA e y+k+
  EEA22817.1 1060 IAQMCISVGLYEEAFEIYKKV 1080
                  78889999***********96 PP

  == domain 3  score: 11.1 bits;  conditional E-value: 0.00032
                  HHHHHHHHHHHTT-HHHHHHHHHHHHH CS
       TPR_8    3 ayynlgsiylklgdyeeAkeyyekale 29  
                   + +l+ ++  l+dy++A+e+ +ka +
  EEA22817.1 1228 NWAKLATTLVHLEDYQAAVECARKANS 1254
                  599*********************966 PP

>> Coatomer_WDAD  Coatomer WD associated region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.3     0.027        33      90     164 ..      50     126 ..      10     137 .. 0.68
   2 ?   -3.4   0.0         3   3.6e+03     121     139 ..     278     296 ..     274     309 .. 0.81
   3 ?    1.6   0.1     0.092   1.1e+02     335     379 ..    1096    1140 ..    1092    1167 .. 0.91
   4 !   13.0   0.2   3.3e-05      0.04     332     371 ..    1238    1277 ..    1212    1303 .. 0.90

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.027
                    XXXX.XXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXX CS
  Coatomer_WDAD  90 svkifknfkekktksikleyqvdkifg...GalLgvkseg.svsfYDweqgklvrridvkkvknVvwsd.dgelvalvsk 164
                    +v i  n+k+++ + ik + ++d+ +     +++ +k ++ ++ ++D+e ++ +++  +++   V+w+  + + + lv++
     EEA22817.1  50 QVII-INLKNNN-EVIKRPINADSAIMhwsRNVIALKAQSrTIQIFDLEAKQKLKSALMSE-DVVYWKWfSETSLGLVTD 126
                    2333.5777777.778888888765555876777776666578888888888888888888.777776413444555555 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 3
                    XXXXXX.XXXXXXXXXXXX CS
  Coatomer_WDAD 121 gvksegsvsfYDweqgklv 139
                    +v++ g++++YD+e+g+ +
     EEA22817.1 278 LVTKYGFIHLYDLETGTCI 296
                    6788999********9987 PP

  == domain 3  score: 1.6 bits;  conditional E-value: 0.092
                     -HHHHHHHHHHH--HHHHHHHHHHHHHTT-HHHHHHHHHHTT-HH CS
  Coatomer_WDAD  335 nLelAlelakelddeekWkkLgdaAlsqgniklaeeayqkakdfd 379 
                      ++ A e a++ + +e+W+k+++a l   +++   e+y ka+d +
     EEA22817.1 1096 SIDRAQEYAERVELPEVWSKVAKAQLDGLRVTDSIESYIKANDAS 1140
                     5899****************************9999999999976 PP

  == domain 4  score: 13.0 bits;  conditional E-value: 3.3e-05
                     HTT-HHHHHHHHHHH--HHHHHHHHHHHHHTT-HHHHHHH CS
  Coatomer_WDAD  332 elgnLelAlelakelddeekWkkLgdaAlsqgniklaeea 371 
                      l++ + A+e+a+++++ ++Wk++++a +++ ++ la+ +
     EEA22817.1 1238 HLEDYQAAVECARKANSVKVWKQVSEACINKKEFRLAQIC 1277
                     4567789*******************************98 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0         4   4.8e+03      11      20 ..     376     385 ..     374     386 .. 0.84
   2 ?   -0.9   0.0       1.8   2.2e+03       2      14 ..     881     893 ..     880     896 .. 0.86
   3 ?    3.2   0.0     0.089   1.1e+02       5      24 ..    1060    1079 ..    1058    1087 .. 0.92
   4 ?    3.2   0.0     0.088     1e+02       5      24 ..    1232    1251 ..    1229    1256 .. 0.88
   5 ?    5.1   0.0     0.022        26       9      28 ..    1295    1312 ..    1288    1320 .. 0.83
   6 ?   -0.5   0.0       1.4   1.7e+03       6      21 ..    1517    1532 ..    1516    1537 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 4
       TPR_7  11 rlGdyeeAie 20 
                 ++G+y+eA++
  EEA22817.1 376 AQGNYSEAAK 385
                 69******96 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 1.8
       TPR_7   2 LlnLarlysrlGd 14 
                 +++La +y + ++
  EEA22817.1 881 YNALAKIYIDSNN 893
                 89******99886 PP

  == domain 3  score: 3.2 bits;  conditional E-value: 0.089
       TPR_7    5 LarlysrlGdyeeAielyeq 24  
                  +a+++ ++G yeeA e+y++
  EEA22817.1 1060 IAQMCISVGLYEEAFEIYKK 1079
                  899***************98 PP

  == domain 4  score: 3.2 bits;  conditional E-value: 0.088
       TPR_7    5 LarlysrlGdyeeAielyeq 24  
                  La + + l dy+ A+e+ ++
  EEA22817.1 1232 LATTLVHLEDYQAAVECARK 1251
                  9999************9776 PP

  == domain 5  score: 5.1 bits;  conditional E-value: 0.022
       TPR_7    9 ysrlGdyeeAielyeqsLal 28  
                  y+r G+++e+i+l+e+  +l
  EEA22817.1 1295 YQRNGYFDELISLLEA--GL 1312
                  99*************9..54 PP

  == domain 6  score: -0.5 bits;  conditional E-value: 1.4
       TPR_7    6 arlysrlGdyeeAiel 21  
                  a++y++  ++e+ i l
  EEA22817.1 1517 ANIYRKNKRWEKSIAL 1532
                  89**********9987 PP

>> VapB_antitoxin  Bacterial antitoxin of type II TA system, VapB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0       8.4     1e+04       9      20 ..     848     859 ..     848     861 .. 0.74
   2 ?   13.0   0.0   6.3e-05     0.075       9      37 ..    1536    1564 ..    1535    1571 .. 0.90

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 8.4
                     XXXXXXXXXXXX CS
  VapB_antitoxin   9 DeLlaeAirltg 20 
                     DeL++e+  + +
      EEA22817.1 848 DELVQEVESRNR 859
                     899999866655 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 6.3e-05
                      XXXXXXXXXXXXXXXXXXXXXXXXXX--- CS
  VapB_antitoxin    9 DeLlaeAirltglktKrEaVnlALreLiq 37  
                      D+L+++Ai+ + +++K+E+V++ Lr ++ 
      EEA22817.1 1536 DKLFKDAIETAAMSGKSEVVEELLRYFVD 1564
                      9*********************9999986 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.1      0.36   4.3e+02      11      22 ..     374     385 ..     372     387 .. 0.87
   2 ?   -1.9   0.0       4.4   5.2e+03       3      16 ..     880     893 ..     879     896 .. 0.85
   3 ?   -0.8   0.0       1.9   2.3e+03       8      26 ..    1061    1079 ..    1058    1080 .. 0.77
   4 ?    6.9   0.1    0.0066       7.8       4      27 ..    1229    1252 ..    1227    1254 .. 0.94
   5 ?    1.6   0.0      0.31   3.7e+02       8      22 ..    1517    1531 ..    1515    1532 .. 0.90

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.36
       TPR_2  11 yyklgdyeeAle 22 
                 ++++g+y eA++
  EEA22817.1 374 LLAQGNYSEAAK 385
                 789*******87 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 4.4
       TPR_2   3 alynlGlayyklgd 16 
                 ++++l+++y+ +++
  EEA22817.1 880 VYNALAKIYIDSNN 893
                 799******99987 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 1.9
       TPR_2    8 GlayyklgdyeeAleafek 26  
                  ++ ++  g yeeA e ++k
  EEA22817.1 1061 AQMCISVGLYEEAFEIYKK 1079
                  6677777889999999987 PP

  == domain 4  score: 6.9 bits;  conditional E-value: 0.0066
       TPR_2    4 lynlGlayyklgdyeeAleafekA 27  
                  +  l+  + +l dy+ A+e+ +kA
  EEA22817.1 1229 WAKLATTLVHLEDYQAAVECARKA 1252
                  788999****************99 PP

  == domain 5  score: 1.6 bits;  conditional E-value: 0.31
       TPR_2    8 GlayyklgdyeeAle 22  
                  +++y+k++++e+ ++
  EEA22817.1 1517 ANIYRKNKRWEKSIA 1531
                  89**********986 PP

>> TPR_1  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.1       1.9   2.3e+03      12      21 ..     375     384 ..     374     385 .. 0.84
   2 ?    0.7   0.0      0.45   5.4e+02       7      27 ..    1060    1080 ..    1059    1080 .. 0.86
   3 ?    6.7   0.0    0.0055       6.6       4      27 ..    1229    1252 ..    1229    1252 .. 0.92
   4 ?    1.4   0.0      0.27   3.2e+02       8      22 ..    1517    1531 ..    1517    1532 .. 0.91

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 1.9
                 HHTT-HHHHH CS
       TPR_1  12 fklgkydeAl 21 
                 + +g+y eA 
  EEA22817.1 375 LAQGNYSEAA 384
                 68******96 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.45
                  HHHHHHHTT-HHHHHHHHHHH CS
       TPR_1    7 lGnayfklgkydeAleyyekA 27  
                  +++++ + g y+eA e y+k+
  EEA22817.1 1060 IAQMCISVGLYEEAFEIYKKV 1080
                  5778888999*******9995 PP

  == domain 3  score: 6.7 bits;  conditional E-value: 0.0055
                  HHHHHHHHHHTT-HHHHHHHHHHH CS
       TPR_1    4 lynlGnayfklgkydeAleyyekA 27  
                  +  l+ ++ +l++y+ A+e+ +kA
  EEA22817.1 1229 WAKLATTLVHLEDYQAAVECARKA 1252
                  677999999***********9998 PP

  == domain 4  score: 1.4 bits;  conditional E-value: 0.27
                  HHHHHHTT-HHHHHH CS
       TPR_1    8 GnayfklgkydeAle 22  
                  +n+y+k++++++ ++
  EEA22817.1 1517 ANIYRKNKRWEKSIA 1531
                  79**********885 PP

>> Utp13  Utp13 specific WD40 associated domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   0.0    0.0055       6.6       1      21 [.     368     388 ..     368     456 .. 0.80
   2 ?   -0.8   0.0       1.1   1.3e+03       3      37 ..     465     499 ..     463     565 .. 0.76
   3 ?    1.8   0.1      0.17     2e+02      16      94 ..     996    1070 ..     991    1106 .. 0.64
   4 ?    2.1   0.1      0.14   1.6e+02       6      51 ..    1235    1280 ..    1219    1310 .. 0.73

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.0055
                 -HHHHHHHHCCHHHHHHHHHH CS
       Utp13   1 eqelqnllrkkdyreAiaLAl 21 
                 +q+++nll++++y+eA ++A 
  EEA22817.1 368 QQQFDNLLAQGNYSEAAKIAA 388
                 7****************9984 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 1.1
                 HHHHHHHCCHHHHHHHHHHHSSSTHHHHHHHHHHH CS
       Utp13   3 elqnllrkkdyreAiaLAlkldqpkrllkllkevl 37 
                 el  l+r +d + A+++ l+ + p++++  + e  
  EEA22817.1 465 ELGDLVRPHDMSLALQIYLQANVPHKVVAGFAETG 499
                 67778899999999999999999999988777664 PP

  == domain 3  score: 1.8 bits;  conditional E-value: 0.17
                  HHHHHHHSSSTHHHHHHHHHHHS-SS--STSSSSSHHHHHH.HHC--HHHHHHHHHHHHHHHTSTTTHHHHHHHHHHHHH CS
       Utp13   16 AiaLAlkldqpkrllkllkevleseeeeeesitgskevdev.lkslskeqleklLkyirdWntnartsevAqrvLnailk 94  
                  A++  l+ d p +l++ll++++ + +      +++++++++ + +  k +  +l++yi   n  +   e+Aq+++++ l 
  EEA22817.1  996 AVKSFLDADLPAELIELLEKIILEPSP----FSDNSSLQNLlMLTAAKADKSRLIDYIHRLNEFN-ADEIAQMCISVGLY 1070
                  5566688899***********977654....2223333333034555556666666666666432.34677777766555 PP

  == domain 4  score: 2.1 bits;  conditional E-value: 0.14
                  HHHHCCHHHHHHHHHHHSSSTHHHHHHHHHHHS-SS--STSSSSSH CS
       Utp13    6 nllrkkdyreAiaLAlkldqpkrllkllkevleseeeeeesitgsk 51  
                   l++ +dy+ A++ A k +  k   ++ +++++++e +  +i g++
  EEA22817.1 1235 TLVHLEDYQAAVECARKANSVKVWKQVSEACINKKEFRLAQICGLN 1280
                  5788888888888888888888888888888888877766666663 PP

>> TPR_14  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.1       2.6   3.1e+03       5      24 ..     368     387 ..     365     390 .. 0.79
   2 ?   -2.0   0.0       8.2   9.8e+03      15      38 ..     625     641 ..     615     646 .. 0.57
   3 ?    0.3   0.0       1.4   1.7e+03       1      26 [.     729     754 ..     729     755 .. 0.90
   4 ?    0.0   0.1       1.8   2.1e+03      11      40 ..    1149    1177 ..    1144    1185 .. 0.69
   5 ?    5.1   0.0     0.041        49       4      27 ..    1229    1252 ..    1227    1266 .. 0.90
   6 ?    5.1   0.0     0.042        50       3      29 ..    1287    1313 ..    1285    1326 .. 0.84

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 2.6
      TPR_14   5 lalaeallalGdpdeAiall 24 
                 ++  + lla+G++ eA++++
  EEA22817.1 368 QQQFDNLLAQGNYSEAAKIA 387
                 56666799********9975 PP

  == domain 2  score: -2.0 bits;  conditional E-value: 8.2
      TPR_14  15 GdpdeAiallrralalaPddaeaw 38 
                 G         +ral+   d+a++ 
  EEA22817.1 625 GL-------IQRALENTEDPAVIK 641
                 44.......456666555555555 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 1.4
      TPR_14   1 peallalaeallalGdpdeAiallrr 26 
                 pe++ ++ ea  a G++ e ++++r+
  EEA22817.1 729 PEVHFKYIEAATAMGQLTEVERICRE 754
                 678899***************99986 PP

  == domain 4  score: 0.0 bits;  conditional E-value: 1.8
      TPR_14   11 llalGdpdeAiallrralalaPddaeawll 40  
                    ++G+ ++ +++lr a ++   ++++ ++
  EEA22817.1 1149 ATHAGKDEDLVKYLRMARKT-LREPAIDTA 1177
                  5689999**********663.333443333 PP

  == domain 5  score: 5.1 bits;  conditional E-value: 0.041
      TPR_14    4 llalaeallalGdpdeAiallrra 27  
                  +++la  l +l+d+++A++++r+a
  EEA22817.1 1229 WAKLATTLVHLEDYQAAVECARKA 1252
                  99********************98 PP

  == domain 6  score: 5.1 bits;  conditional E-value: 0.042
      TPR_14    3 allalaeallalGdpdeAiallrrala 29  
                   l +l++ + ++G +de i ll++ l 
  EEA22817.1 1287 ELNDLVKQYQRNGYFDELISLLEAGLG 1313
                  566899******************985 PP

>> Vps39_1  Vacuolar sorting protein 39 domain 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.1      0.18   2.1e+02      23      69 ..     631     678 ..     609     709 .. 0.79
   2 ?    1.8   0.2      0.24   2.9e+02      16      45 ..     747     776 ..     740     816 .. 0.77
   3 ?    4.7   0.1      0.03        35      10      69 ..    1038    1098 ..    1031    1113 .. 0.82
   4 ?    6.7   0.0    0.0072       8.6       1      52 [.    1174    1226 ..    1174    1261 .. 0.81
   5 ?    2.1   0.0       0.2   2.4e+02      35      75 ..    1356    1398 ..    1328    1412 .. 0.72
   6 ?   -1.4   0.0       2.3   2.8e+03       6      43 ..    1413    1451 ..    1408    1511 .. 0.67

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.18
     Vps39_1  23 leNaCdlkdveeiLkkekkyk.eLidlYygkklheeALeLlkeladed 69 
                 leN  d+ +++++L k  k++ e ++ Y g+   e+ALe l e+ +++
  EEA22817.1 631 LENTEDPAVIKRNLVKTDKLNpEWLIKYFGRLSQEQALEGLDEMLNSN 678
                 679999********999988646677788999999****999999842 PP

  == domain 2  score: 1.8 bits;  conditional E-value: 0.24
     Vps39_1  16 lvgpLlrleNaCdlkdveeiLkkekkykeL 45 
                 +v  ++r +N+ ++++v+++Lk+++ +++L
  EEA22817.1 747 EVERICRESNYYNPEKVKNFLKEANLTEQL 776
                 677788888999999999999777766665 PP

  == domain 3  score: 4.7 bits;  conditional E-value: 0.03
     Vps39_1   10 lktkpklvgpLlrleNaCdlkdveeiLkkekkykeLidlYygkklheeALeLlkelade.d 69  
                  +k++++ +++ +   N+ + +++ ++  +   y+e ++ Y++ ++h +A ++l+e + + d
  EEA22817.1 1038 AKADKSRLIDYIHRLNEFNADEIAQMCISVGLYEEAFEIYKKVNNHTAATDVLVENIVSiD 1098
                  56678888889988999999*******************************9998776433 PP

  == domain 4  score: 6.7 bits;  conditional E-value: 0.0072
     Vps39_1    1 iDTaLlkvYlkt.kpklvgpLlrleNaCdlkdveeiLkkekkykeLidlYygk 52  
                  iDTaL  +++++ + +++ ++lr  N  d++ +     +e  +++  ++Y + 
  EEA22817.1 1174 IDTALAFCFARLdQLAELEDFLRATNVADVEASGDKAYEEGFHEAAKIFYTSI 1226
                  8***********8899***************9988887777777777777665 PP

  == domain 5  score: 2.1 bits;  conditional E-value: 0.2
     Vps39_1   35 iLkkekkykeLidlY.ygkklheeALeLlkelade.deedeed 75  
                    ++++ + eL+ lY ++ + +++AL ++++ a++ ++++ +d
  EEA22817.1 1356 ATEEANLWPELVFLYcHYDEWDNAALAMMERAAEAwEHHSFKD 1398
                  5578999*******955678899********999854444444 PP

  == domain 6  score: -1.4 bits;  conditional E-value: 2.3
     Vps39_1    6 lkvYlktkpklvgpLlrle.NaCdlkdveeiLkkekkyk 43  
                  l  Yl+ +p l+ +Ll++   + d++ v +i +++ ++ 
  EEA22817.1 1413 LNFYLQEQPLLLTDLLQVLtARIDVSRVVRIFQSSDNIP 1451
                  678999999999999988757778887777777666654 PP

>> DUF1400  Alpha/beta hydrolase of unknown function (DUF1400)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.2      0.14   1.7e+02      13      87 ..     484     560 ..     476     586 .. 0.66
   2 ?    1.9   0.0      0.21   2.5e+02      23      68 ..     643     690 ..     633     731 .. 0.74
   3 ?    6.4   0.0    0.0084        10      60     118 ..     993    1051 ..     987    1060 .. 0.89
   4 ?   -0.8   0.1       1.5   1.8e+03      33      71 ..    1412    1447 ..    1402    1485 .. 0.70

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.14
     DUF1400  13 ersisvedLekfaktgevsseLatylk.llskeqreelreaLqaeiklspvllsqllnspigekl.Lerlgeviqte 87 
                 + +++ +    fa+tg++++ L    +   +++  + l+ + + +++   ++++ql n ++g  + L+r+ +v+ ++
  EEA22817.1 484 QANVPHKVVAGFAETGQFDKILPYAKQtGYQPDFTQLLQHIVRLNPEKGAEFAAQLANEETGALVdLDRVVDVFLSQ 560
                 55666677788999999998886555534555556666666666666667788888888888766566666666554 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.21
     DUF1400  23 kfaktgevsse.Latylkllskeq.reelreaLqaeiklspvllsqll 68 
                 +++kt ++++e L +y+ +ls+eq  e l e+L+ +i  + +++ q+ 
  EEA22817.1 643 NLVKTDKLNPEwLIKYFGRLSQEQaLEGLDEMLNSNIRQNLQAVVQIA 690
                 567787777765677777666554267788899888888888877765 PP

  == domain 3  score: 6.4 bits;  conditional E-value: 0.0084
     DUF1400   60 spvllsqllnspigeklLerlgeviqtesdqngkealrsAlilaaadpeglsllnfLrk 118 
                   +v+++ +l+ ++  +l+e l+++i ++s  ++  +l++ l+l aa+ ++  l++ +  
  EEA22817.1  993 VSVAVKSFLDADLPAELIELLEKIILEPSPFSDNSSLQNLLMLTAAKADKSRLIDYIHR 1051
                  57899***********************99999***************99999998765 PP

  == domain 4  score: -0.8 bits;  conditional E-value: 1.5
     DUF1400   33 eLatylkllskeqreelreaLqaeiklspvllsqllnsp 71  
                   L++yl+  ++   ++l ++L+a+i++s v+  ++++s+
  EEA22817.1 1412 ALNFYLQ-EQPLLLTDLLQVLTARIDVSRVV--RIFQSS 1447
                  6888888.88888899999999999997654..455554 PP

>> Rop  Rop protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   0.1   0.00069      0.83      22      53 ..    1048    1081 ..    1030    1084 .. 0.81
   2 ?   -3.2   0.4       6.6   7.8e+03      14      29 ..    1416    1431 ..    1412    1433 .. 0.80

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.00069
         Rop   22 LLeKLneLdlDeqAdlCEr..LHedAeeLyrsls 53  
                   + +Lne ++De A++C +  L e+A e+y++++
  EEA22817.1 1048 YIHRLNEFNADEIAQMCISvgLYEEAFEIYKKVN 1081
                  5789*************865599***99999876 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 6.6
         Rop   14 FIksQsLlLLeKLneL 29  
                  ++++Q LlL + L+ L
  EEA22817.1 1416 YLQEQPLLLTDLLQVL 1431
                  689******9988766 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.1       1.8   2.2e+03      18      33 ..     372     387 ..     365     392 .. 0.54
   2 ?    2.8   0.0      0.12   1.4e+02      11      36 ..    1062    1080 ..    1055    1087 .. 0.57
   3 ?    4.7   0.1     0.032        38       8      29 ..    1231    1252 ..    1223    1254 .. 0.76
   4 ?   -3.0   0.2       7.9   9.5e+03      22      34 ..    1380    1392 ..    1377    1393 .. 0.71
   5 ?    1.3   0.0      0.35   4.2e+02      10      26 ..    1517    1533 ..    1500    1535 .. 0.89

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 1.8
      TPR_12  18 rydeAlellekaleia 33 
                 +   A+ ++ +a  ia
  EEA22817.1 372 DNLLAQGNYSEAAKIA 387
                 4444555555554444 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.12
      TPR_12   11 avlrrlgrydeAlellekaleiarrl 36  
                  +++   g y+eA+e+++k       +
  EEA22817.1 1062 QMCISVGLYEEAFEIYKK-------V 1080
                  555555555555555554.......3 PP

  == domain 3  score: 4.7 bits;  conditional E-value: 0.032
      TPR_12    8 nlaavlrrlgrydeAlelleka 29  
                  +la++l +l++y+ A e+ +ka
  EEA22817.1 1231 KLATTLVHLEDYQAAVECARKA 1252
                  6888899999999998888876 PP

  == domain 4  score: -3.0 bits;  conditional E-value: 7.9
      TPR_12   22 Alellekaleiar 34  
                  Al++ e+a e+++
  EEA22817.1 1380 ALAMMERAAEAWE 1392
                  7777777777775 PP

  == domain 5  score: 1.3 bits;  conditional E-value: 0.35
      TPR_12   10 aavlrrlgrydeAlell 26  
                  a+++r+ +r++++++l 
  EEA22817.1 1517 ANIYRKNKRWEKSIALS 1533
                  899999*****999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1675 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       938  (0.0523175); expected 358.6 (0.02)
Passed bias filter:                      629  (0.0350828); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 1.06u 0.28s 00:00:01.34 Elapsed: 00:00:00.49
# Mc/sec: 10185.68
//
Query:       EEA22818.1  [L=1191]
Description: pyruvate carboxylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.9e-81  271.3   0.1    7.7e-81  270.6   0.1    1.3  1  CPSase_L_D2      Carbamoyl-phosphate synthase L chain, ATP bi
    7.9e-70  234.6   0.0    1.3e-69  233.9   0.0    1.4  1  PYC_OADA         Conserved carboxylase domain
      6e-39  133.0   0.0    1.2e-38  132.0   0.0    1.6  1  Biotin_carb_N    Biotin carboxylase, N-terminal domain
    2.1e-30  105.0   0.0    8.9e-30  103.0   0.0    2.1  2  Biotin_carb_C    Biotin carboxylase C-terminal domain
    3.3e-27   95.7   0.0    5.8e-27   94.9   0.0    1.4  1  HMGL-like        HMGL-like
    9.7e-18   63.8   4.7      2e-17   62.8   3.0    2.3  2  Biotin_lipoyl    Biotin-requiring enzyme
    5.1e-11   42.2   1.6    3.4e-07   30.0   0.1    3.2  3  Biotin_lipoyl_2  Biotin-lipoyl like
    4.5e-10   39.4   0.0    8.9e-10   38.4   0.0    1.4  1  Dala_Dala_lig_C  D-ala D-ala ligase C-terminus
    6.3e-07   29.1   0.0    1.3e-06   28.2   0.0    1.4  1  ATP-grasp        ATP-grasp domain
    1.7e-05   24.9   0.0    3.5e-05   23.9   0.0    1.5  1  ATP-grasp_3      ATP-grasp domain
    3.8e-05   23.4   0.0    7.9e-05   22.3   0.0    1.5  1  RimK             RimK-like ATP-grasp domain
    0.00013   21.2   0.1     0.0033   16.7   0.0    2.3  2  HlyD_D23         Barrel-sandwich domain of CusB or HlyD membr
     0.0048   17.6   0.5        3.5    8.4   0.0    3.6  4  HlyD_3           HlyD family secretion protein
     0.0071   16.1   0.0      0.015   15.0   0.0    1.5  1  GARS_A           Phosphoribosylglycinamide synthetase, ATP-gr
     0.0097   15.5   0.0      0.026   14.1   0.0    1.8  2  ATP-grasp_4      ATP-grasp domain
  ------ inclusion threshold ------
      0.054   12.7   0.0       0.26   10.5   0.0    2.0  2  ATPgrasp_ST      Sugar-transfer associated ATP-grasp
      0.058   13.3   0.1       0.17   11.9   0.1    1.7  1  DUF2118          Uncharacterized protein conserved in archaea


Domain annotation for each model (and alignments):
>> CPSase_L_D2  Carbamoyl-phosphate synthase L chain, ATP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  270.6   0.1   7.3e-84   7.7e-81       1     210 [.     157     365 ..     157     366 .. 0.99

  Alignments for each domain:
  == domain 1  score: 270.6 bits;  conditional E-value: 7.3e-84
                  SHHHHHHHHHHTT-BBSSEECSSBSSHHHHHHHHHHH-SSEEEEETTCCTTTTEEEESSHHHHHHHHHHHHHHHHHHHSTS-EEEEE--SSSEEEEEE CS
  CPSase_L_D2   1 DkesakealkkinvpvvpssaapvetleealaiakeigyPviikaafglGGkGmrvarneeelaelvkkalaeakaafgnkqvlvekslkgpkeiEve 98 
                  Dk+sa++++ k nvpvvp++++pve+ e+a a+++e+g+P+iikaafg+GG+Gmrv+r++e l++++ +a++ea++afgn +v++e++l++pk+iEv+
   EEA22818.1 157 DKVSARKLAIKCNVPVVPGTPGPVEKFEDAKAFTDEYGFPIIIKAAFGGGGRGMRVVREQESLKDAFDRATSEARSAFGNGTVFIERFLDKPKHIEVQ 254
                  9************************************************************************************************* PP

                  EEEETTS-EEEEEEEEECCECTCCCCEEEES-SS--HHHHHHHHHHHHHHHHHHT-EEEEEEEEEEETTTTEEEEEEEESS--CCHHHHHHHHS--HH CS
  CPSase_L_D2  99 vlrDakgnvitvcerenslqlrtqkvievAPsqtLtdeerqalreaavkvvrevgvvgagtveflldpkskeyyviEvNtRlsvesalaekaTGldlv 196
                  +l D++gnv+++ er++s+q+r+qkv+e AP++ L  e r+++ ++av+++++v++++agt efl+d+ +++yy+iE+N+R++ve++++e++TG+d+v
   EEA22818.1 255 LLGDNQGNVVHLYERDCSVQRRHQKVVELAPAKDLPVEVRDKILADAVTLAKSVNYRNAGTAEFLVDQ-QNRYYFIEINPRIQVEHTITEEITGIDIV 351
                  *******************************************************************8.9**************************** PP

                  HHHHHHHTT--GCG CS
  CPSase_L_D2 197 keaakialgekLee 210
                  +++++ia+g++Le+
   EEA22818.1 352 AAQIQIAAGATLEQ 365
                  ************97 PP

>> PYC_OADA  Conserved carboxylase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  233.9   0.0   1.3e-72   1.3e-69       1     197 [.     873    1071 ..     873    1072 .. 0.98

  Alignments for each domain:
  == domain 1  score: 233.9 bits;  conditional E-value: 1.3e-72
                  HHCCT--CCHHHHHHHHHHHTT-GGGHHHHHHHHHHHHHHTT----STTHHHHHHHHHHHHHHH........TS.TTSS--HHHHHHHTTSS---SS CS
    PYC_OADA    1 VykheiPGGqltnlkeqakeqglldkfeevlkeyaevnkllGdivkVTPsSkvvgdlAvfnvlnklteedvleegrykdipdsvvdllkGelGkppg 97  
                  Vy+heiPGGqltnl +qa+++gl+ ++ e +k+y+++n+llGdivkVTP+SkvvgdlA+f+v+nkl+++dv+++++ +d+p sv ++l+G +G+p+g
  EEA22818.1  873 VYEHEIPGGQLTNLLFQATQLGLGTQWAETKKAYEAANDLLGDIVKVTPTSKVVGDLAQFMVSNKLSAQDVVDRAEHLDFPGSVLEFLEGLMGQPYG 969 
                  9************************************************************************************************ PP

                  ---HHHHHHHHT.-----S-GGGG---.-HHHHHHHTTTTSS..SHHHHHHHHHSHHHHHHHHHHHHHHHHHH..CTTTS......-SEEEEEETTE CS
    PYC_OADA   98 gfpeelvkkvlkgeepitsrpadslepedleklrkeleekak..teedvlsyalypkvaekflkfreeygdvsvlptkvffeglkvgeevevevegg 192 
                  gfpe+l++++l++++++++rp+  lep dl k+++e++ek++  te dv sya+ypkv+e++ kf ++ygd+svlpt+ f++  ++gee++ve+e+g
  EEA22818.1  970 GFPEPLRSRALRNRRKLDKRPGLYLEPLDLVKIKNEIKEKFGtaTETDVASYAMYPKVFEAYRKFIQKYGDLSVLPTRYFLARPEIGEEFHVELEQG 1066
                  *****************************************66699*************************************************** PP

                  EEE.E CS
    PYC_OADA  193 kyliv 197 
                  k+li 
  EEA22818.1 1067 KVLIL 1071
                  *9975 PP

>> Biotin_carb_N  Biotin carboxylase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.0   0.0   1.2e-41   1.2e-38       2     110 .]      41     152 ..      40     152 .. 0.95

  Alignments for each domain:
  == domain 1  score: 132.0 bits;  conditional E-value: 1.2e-41
                    --EEEE---HHHHHHHHHHHHHTT-EEEEEEEGGGTTSHHHHHSSEEEEEE...SSTTCCGGG-HHHHHHHHHHTT-SEEE--SSTTTT-HHHHHH CS
  Biotin_carb_N   2 ikkvlianrGeiAvriiravrelgietvavyseedanslhvreadeavelg...pasasesYlniekivkaakesgadavhpGyGflsEnaefaea 94 
                    ++k+l+anrGei +ri+r+++el+++tvavys ed+ s+h ++adea+ +g   + ++  +Yl  ++i+k+a e+g++ +hpGyGflsEnaefa++
     EEA22818.1  41 FQKILVANRGEIPIRIFRTAHELSLQTVAVYSWEDRLSMHRQKADEAYIIGtrgQYTPVGAYLAGDEIIKIALEHGVQLIHPGYGFLSENAEFARN 136
                    89************************************************9533345679************************************ PP

                    HHHTT-EESSS-HHHH CS
  Biotin_carb_N  95 veeagivfiGPsaeal 110
                    ve+ag+vf+GP++e++
     EEA22818.1 137 VEKAGLVFVGPTPETI 152
                    ************9986 PP

>> Biotin_carb_C  Biotin carboxylase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.0   0.0   8.4e-33   8.9e-30       1     107 [.     381     488 ..     381     489 .. 0.98
   2 ?   -1.9   0.0       3.3   3.5e+03       2      31 ..    1112    1143 ..    1111    1147 .. 0.80

  Alignments for each domain:
  == domain 1  score: 103.0 bits;  conditional E-value: 8.4e-33
                    EEEEESEETTTTTEE--CE-SEEE---STTEEEEE---.TT-EE-TTS-SEEEEEEEEESSHHHHHHHHHHHHHT-EEESS-BSHHHHHHHHH-HH CS
  Biotin_carb_C   1 eaRinaEdpeknflpssGkvtelelpegpgvRvdsgve.egsevspyyDsllaKlivhgetreealarlrraLaelrieGvktnieflrailedee 95 
                    ++Ri++Edp+k f+p+ Gk++ ++  +g+gvR+d g   +g+ ++p+yDs+l K  + g+t e a +++ raL e+ri+Gvktni+fl ++l++++
     EEA22818.1 381 QCRITTEDPSKAFSPDIGKIEVYRSAGGNGVRLDGGNGfAGAIITPHYDSMLVKCTCLGSTYEIARRKMIRALIEFRIRGVKTNIPFLTSLLSHPT 476
                    79********************************998779******************************************************** PP

                    HHHT---TTTCC CS
  Biotin_carb_C  96 fakgeldtkfle 107
                    f++g++ t+f++
     EEA22818.1 477 FIDGTCWTTFID 488
                    **********98 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 3.3
                     EEEESE..ETTTTTEE--CE-SEEE---STTE CS
  Biotin_carb_C    2 aRinaE..dpeknflpssGkvtelelpegpgv 31  
                     aR+ a   d+++  +p sG v el++ +g +v
     EEA22818.1 1112 ARVKADpnDSSQVGAPMSGVVVELRVHDGSEV 1143
                     6788876566777799********99998887 PP

>> HMGL-like  HMGL-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.9   0.0   5.5e-30   5.8e-27       4     260 ..     580     848 ..     578     851 .. 0.88

  Alignments for each domain:
  == domain 1  score: 94.9 bits;  conditional E-value: 5.5e-30
                 EEE-TTTHHHHTS.SS---HHHHHHHHHHHHHH..T-SEE--........TSGGGT.THHHHHHHS---TT-B...........--EE-SSHHHHHHHH CS
   HMGL-like   4 ivdttLRDGeqal.kaalsveeklaiakaLdea..gvdeiEv........gfpaaseddfevvraiakavkka......r...ilalvrarekdikaav 82 
                 i+dtt RD++q+l ++++++ + l+ia++ + a     ++E+         ++++ ed+++++r++ kav++       r    +a+  + ++ i  + 
  EEA22818.1 580 IMDTTWRDAHQSLlATRVRTVDFLNIARETSYAlsNAYSLECwggatfdvAMRFLYEDPWDRLRKLRKAVPNIpfqmllRganGVAYSSLPDNAIYHFC 678
                 89**********999************986655224457888888888889*******************998666665155688999999******** PP

                 H....TT-SEEEEEEES-HHHHHHHHSSTHHHHHHHHHHHHHHHHHTT-ETTT-B.TTTBS--HHHHHHHHHHHHHHT-SEEEEEETTS---HHHHHHH CS
   HMGL-like  83 ealkgagakrvhvfiatselhlkaklkkdreevakkaeeavkaarslgkdvelsl.edasrtdleflaevveaaeeaGatriniaDtvGvltPneaael 180
                 + +k++g+++++vf+a ++        +d+ ev  ka++a   + +++  ++  + +  ++ +le+ +++v++++++G   + i+D+ Gvl+P++a  l
  EEA22818.1 679 KHAKKNGVDIFRVFDALND--------IDQLEVGIKAVQAAGGVVEATVCYSGDMlNPHKKYNLEYYLNLVDKIVALGTHVLGIKDMAGVLKPQAATLL 769
                 *******************........6666676666666666666666655544144567899*********************************** PP

                 HHHHHHHS-.GGGEEEEEB-TTS-HHHHHHHHHHTT--EEEEBTTS--SSBBB-BHHHHHHHHHHTT-B----HHHHHHH CS
   HMGL-like 181 isalkervkdkvilsvHcHndlGlAvantlaAveaGadrvdgtvnGlGeraGnaaleelvaalealgvdtgldlqklrsi 260
                 i  ++++++  ++++vH+H+  G++v  ++a ++aGad vd++  ++++ +  +++ ++ a le++++d++l+++++r+i
  EEA22818.1 770 IGSIRKKYP-DLPIHVHTHDSAGTGVTSMVACAQAGADAVDAATDSMSGMTSQPSIGAILASLEGTEWDPKLNIRHVRAI 848
                 *********.9****************************************************************99987 PP

>> Biotin_lipoyl  Biotin-requiring enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0       1.3   1.4e+03      44      63 ..    1087    1106 ..    1085    1111 .. 0.80
   2 !   62.8   3.0   1.9e-20     2e-17       2      73 .]    1123    1189 ..    1122    1189 .. 0.97

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 1.3
                     EEEBSSSEEEEEESSTTTEE CS
  Biotin_lipoyl   44 eieapkaGvvkeilvkeGdt 63  
                     e+ ++++G v ++ v+++++
     EEA22818.1 1087 EVFYEMNGEVRQVTVDDNKA 1106
                     778899*********97765 PP

  == domain 2  score: 62.8 bits;  conditional E-value: 1.9e-20
                     EEEESSSEEEEEE.ECSESSSTTCEE-TTSEEEEEECTTEEEEEEBSSSEEEEEESSTTTEEE-TTCEEEEE CS
  Biotin_lipoyl    2 eiksPmiGesveegvvevlvkvGdkVkagqvlaeveamKmemeieapkaGvvkeilvkeGdtvevgdllaki 73  
                     ++ +Pm G++ve       v++G++Vk+g+++a+++amKmem i+ap+ G+v+ + vkeGd+v+  dl++ki
     EEA22818.1 1123 QVGAPMSGVVVE-----LRVHDGSEVKKGDPIAVLSAMKMEMVISAPHHGKVAGLAVKEGDSVDGQDLVCKI 1189
                     7999*******9.....***************************************************9997 PP

>> Biotin_lipoyl_2  Biotin-lipoyl like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.0       1.4   1.5e+03      10      22 ..    1093    1105 ..    1087    1106 .. 0.87
   2 !   30.0   0.1   3.3e-10   3.4e-07       3      34 ..    1122    1153 ..    1120    1159 .. 0.90
   3 !    9.4   0.0   0.00089      0.93       5      24 ..    1161    1180 ..    1158    1185 .. 0.93

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 1.4
  Biotin_lipoyl_2   10 sGrVaqlnVkdGq 22  
                       +G V q+ V d++
       EEA22818.1 1093 NGEVRQVTVDDNK 1105
                       799********97 PP

  == domain 2  score: 30.0 bits;  conditional E-value: 3.3e-10
  Biotin_lipoyl_2    3 vsIaapvsGrVaqlnVkdGqrVkaGdvLaelD 34  
                        ++ ap sG+V++l+V+dG +Vk+Gd +a+l 
       EEA22818.1 1122 SQVGAPMSGVVVELRVHDGSEVKKGDPIAVLS 1153
                       688899***********************997 PP

  == domain 3  score: 9.4 bits;  conditional E-value: 0.00089
  Biotin_lipoyl_2    5 IaapvsGrVaqlnVkdGqrV 24  
                       I+ap  G+Va l+Vk+G+ V
       EEA22818.1 1161 ISAPHHGKVAGLAVKEGDSV 1180
                       89999*************99 PP

>> Dala_Dala_lig_C  D-ala D-ala ligase C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.4   0.0   8.4e-13   8.9e-10      29     174 ..     187     333 ..     178     334 .. 0.87

  Alignments for each domain:
  == domain 1  score: 38.4 bits;  conditional E-value: 8.4e-13
                      HHHHHHC-SSEEEEESSSSTTTTEEEESSGGGHHHHHHHHHTT......-SCEEEEE--.ESEEEEEEEEETSSCEEEEEEEEE-SSSSS-HHH CS
  Dala_Dala_lig_C  29 ekveeelgypvfVKpareGSSvGvskveseeelkeaieeafky......dekvlvEeai.egreievavlgneklevsevgeivvkkgfydyea 115
                      ++ ++e g+p+++K+a  G   G+  v+ +e lk+a+++a +       + +v++E+++ + + iev +lg+++ +v ++ e+  +    + ++
       EEA22818.1 187 KAFTDEYGFPIIIKAAFGGGGRGMRVVREQESLKDAFDRATSEarsafgNGTVFIERFLdKPKHIEVQLLGDNQGNVVHLYERDCSV--QRRHQ 278
                      5678899*******************************99886222223468*******999*********9999999999987764..34455 PP

                      HHC.TT-EEESS----HHHHHHHHHHHHHHHHHTT--SEEEEEEEEETTTEEEEEEEES CS
  Dala_Dala_lig_C 116 kysddkaqlevpaklekeveekiqelalkaykaldlrGlaRvDfflteegeivlnEvNt 174
                      k     ++l    +l+ ev++ki + a+   k ++ r  +   f+++++++ ++ E+N+
       EEA22818.1 279 KV----VELAPAKDLPVEVRDKILADAVTLAKSVNYRNAGTAEFLVDQQNRYYFIEINP 333
                      55....68888889********************************************6 PP

>> ATP-grasp  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.2   0.0   1.2e-09   1.3e-06      14     160 ..     180     335 ..     175     339 .. 0.91

  Alignments for each domain:
  == domain 1  score: 28.2 bits;  conditional E-value: 1.2e-09
                 ECCHHHHHHHHHHH-SCEEEEESSS-CTTTTEEEECTCCGHHCHHHHC........GTTCEEEEE----SEEEEEEEEEETTC-.EEE--EEEEEEETT CS
   ATP-grasp  14 veskeeleeaaeelglpvvvKarrlgydGkGqsvvrseedleqaleal........keekvivEefvpfekElsvlvvrsaeGe.tafypvvetvqedg 103
                 ve+ e+++++++e g+p+++K +  g  G+G  vvr++e+l++a++ +        ++++v +E f +  k + v    + +G+ ++ y+    vq++ 
  EEA22818.1 180 VEKFEDAKAFTDEYGFPIIIK-AAFGGGGRGMRVVREQESLKDAFDRAtsearsafGNGTVFIERFLDKPKHIEVQLLGDNQGNvVHLYERDCSVQRRH 277
                 677889999************.788889*****************9999999**999***********9999999999999999678999999999999 PP

                 EEEEEEECEE.-SCHHHHHHHHHHHHHHHHHTSSEEEEEEEEEETTCTEEEEEEESS- CS
   ATP-grasp 104 ilrlsvapae.vsekaqkkaeeiakkiveeLggvGvfavElFvledgellvnElapRp 160
                   ++ +apa+ ++ +   k+ + a ++++++++    + E+ v ++++ ++ E+ pR 
  EEA22818.1 278 QKVVELAPAKdLPVEVRDKILADAVTLAKSVNYRNAGTAEFLVDQQNRYYFIEINPRI 335
                 9999999985378889999999999*********99999*99998888********95 PP

>> ATP-grasp_3  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.0   3.3e-08   3.5e-05      20     159 ..     181     336 ..     156     338 .. 0.80

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 3.3e-08
                  ....-EESS--..SSSEEEEESS-------B--SS--TTE...................EEEE---.SEEEEEEEEE.SSSEEEEEEEEE.EEET... CS
  ATP-grasp_3  20 tkleaeeleee..ekklvvKprdGaggesvrvveekeeaeaaieeve............lvqefie.GkplSvsllsdgekvlvlavnrq.liekaek 101
                  +k e++++       ++++K + G+gg ++rvv+e+e+++ a++  +             + +f++  k++ v+ll+d++ ++v    r   ++++++
   EEA22818.1 181 EKFEDAKAFTDeyGFPIIIKAAFGGGGRGMRVVREQESLKDAFDRATsearsafgngtvFIERFLDkPKHIEVQLLGDNQGNVVHLYERDcSVQRRHQ 278
                  44444444333225589***********************9999888999********98888985379********998877655555516777777 PP

                  .TEEEEEEES----HHHHHHHHHHHHHTTSTT--EEEEEEEEESS..SEEEEEEESS-- CS
  ATP-grasp_3 102 efvyaGnvtpietelkeevvelaeevvekleglaGyvGvDlvlkd.eepyviEvNPRlt 159
                  ++v      + ++e ++++ + a  + +++ + +     ++++ + +  y+iE+NPR++
   EEA22818.1 279 KVVELAPAKDLPVEVRDKILADAVTLAKSV-NYRNAGTAEFLVDQqNRYYFIEINPRIQ 336
                  79999999999999****************.777777778887776999********98 PP

>> RimK  RimK-like ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.3   0.0   7.4e-08   7.9e-05      25     182 ..     181     352 ..     156     358 .. 0.76

  Alignments for each domain:
  == domain 1  score: 22.3 bits;  conditional E-value: 7.4e-08
                 SS-S-HHHHHHTT-.-SSEEEEE-TTTT--EEEEE-SHHHHHHHHHH.........GGG--EEEEE--SS-SEEEEEEEET.TEEEEEEEEE--SSS-- CS
        RimK  25 rdeedaekliekiklrfPvvvKsvegsqGikvvlakkeqklkqvlea.........lkeailvqeyieeaenediRvlvvd.devvaalrrvskeGdFR 113
                 ++ eda+++ +++  +fP+++K  +g  G ++ + +++++lk+ ++           + ++++  ++++ +  ++ +l  + ++vv  ++r +      
  EEA22818.1 181 EKFEDAKAFTDEY--GFPIIIKAAFGGGGRGMRVVREQESLKDAFDRatsearsafGNGTVFIERFLDKPKHIEVQLLGDNqGNVVHLYERDCSVQRRH 277
                 66799*******9..6***************************9997554444444444559**********999999765268999999986653333 PP

                 --TTTT-EEE..E----HHHHHHHHHHHHHCT-SEEEEE..EEEETTEEEEEEEESS--SHH..HHHHHT--HHH CS
        RimK 114 snlhrGgvae..klqlseeekelAikaakamelvvaGvD..llrakrgllvlEvnsspglek..iektlgidiak 182
                   +   + a+  ++++ ++    A++ ak ++   aG    l+++++ ++++E+n   ++e+   e  +gidi +
  EEA22818.1 278 QKVVELAPAKdlPVEVRDKILADAVTLAKSVNYRNAGTAefLVDQQNRYYFIEINPRIQVEHtiTEEITGIDIVA 352
                 4444444444015555566666689************988999*************9998862257788999854 PP

>> HlyD_D23  Barrel-sandwich domain of CusB or HlyD membrane-fusion
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   3.1e-06    0.0033       5      54 ..    1107    1155 ..    1103    1159 .. 0.81
   2 ?    2.9   0.0     0.053        55     106     140 ..    1156    1190 ..    1153    1191 .] 0.88

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 3.1e-06
                  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
    HlyD_D23    5 tlravGtvayderrlarvsarveGwveklyvnatgdkVkkGqpLaelysp 54  
                  +++ +++v++d ++ ++v a ++G v +l+v+  g++VkkG+p+a l + 
  EEA22818.1 1107 AVDNTARVKADPNDSSQVGAPMSGVVVELRVH-DGSEVKKGDPIAVLSAM 1155
                  56778889999999999999999999999998.89999999998887665 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.053
                  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
    HlyD_D23  106 qktvtvkapisGvVteknvreGqyvqpgdtlftia 140 
                  + ++ ++ap +G V  ++v eG+ v+ +d + +i+
  EEA22818.1 1156 KMEMVISAPHHGKVAGLAVKEGDSVDGQDLVCKIS 1190
                  567899*******************9999888886 PP

>> HlyD_3  HlyD family secretion protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0         9   9.5e+03      19      40 ..     272     293 ..     260     294 .. 0.75
   2 ?   -0.5   0.0         2   2.1e+03      52      96 ..    1054    1104 ..    1042    1116 .. 0.70
   3 !    8.4   0.0    0.0033       3.5       2      31 ..    1124    1153 ..    1123    1159 .. 0.90
   4 ?    4.6   0.0     0.048        51       2      30 ..    1161    1189 ..    1160    1191 .] 0.92

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 9
      HlyD_3  19 evvqagdelleiippdtllvea 40 
                 +v ++ ++++e++p ++l ve+
  EEA22818.1 272 SVQRRHQKVVELAPAKDLPVEV 293
                 55568899*******9999998 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 2
      HlyD_3   52 kkgqkvtlkldqgsdytlkgkierisptvdaktg...aykv.....evslenp 96  
                  ++g + +++l+qg+  +l  k+  i+p ++++++    y++     +v+++++
  EEA22818.1 1054 EIGEEFHVELEQGK--VLILKLLAIGPLSEQTGQrevFYEMngevrQVTVDDN 1104
                  56888999998665..99*********77765553324444444455555555 PP

  == domain 3  score: 8.4 bits;  conditional E-value: 0.0033
      HlyD_3    2 lrApvdGvvvelnveegevvqagdelleii 31  
                  + Ap +Gvvvel v  g+ v +gd+++ + 
  EEA22818.1 1124 VGAPMSGVVVELRVHDGSEVKKGDPIAVLS 1153
                  569***********99999*******9875 PP

  == domain 4  score: 4.6 bits;  conditional E-value: 0.048
      HlyD_3    2 lrApvdGvvvelnveegevvqagdellei 30  
                  + Ap  G+v+ l v+eg+ v  +d + +i
  EEA22818.1 1161 ISAPHHGKVAGLAVKEGDSVDGQDLVCKI 1189
                  88**********************99988 PP

>> GARS_A  Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   1.4e-05     0.015       2      91 ..     157     247 ..     156     277 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.4e-05
                 BHHHHHHHHHHTT--B-..-EEEESSHHHHHHHHHHHSSSEEEEEESC-GGGT-EEEESSHHHHHHHHHHHCTS-TTCCCCSSEEEEE---S CS
      GARS_A   2 sKsfakdllkkagipta..eyeaftdpeeakeyieeatakalVvKadglaagKgvivakseeealkavkeilekkkfGeagekvviEelleG 91 
                 +K  a++l  k+++p    +   +++ e+ak++ +e ++++ ++Ka+   +g+g+ v++++e   +a +   ++ +    + +v iE +l+ 
  EEA22818.1 157 DKVSARKLAIKCNVPVVpgTPGPVEKFEDAKAFTDEYGFPI-IIKAAFGGGGRGMRVVREQESLKDAFDRATSEARSAFGNGTVFIERFLDK 247
                 7888999999999998745667899****************.****************9998888888888877655555999******974 PP

>> ATP-grasp_4  ATP-grasp domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.1   0.0   2.5e-05     0.026       2     152 ..     194     335 ..     193     343 .. 0.82
   2 ?   -3.5   0.0       6.4   6.8e+03      63     102 ..    1056    1093 ..    1034    1113 .. 0.68

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 2.5e-05
  ATP-grasp_4   2 slPvviKPsvgffSlGVykinneeewkaavaaieeeleqakeeykeevveeesflvEeyieG.eEfavdayfdeeGepvilnilkkefaseedvsdrl 98 
                   +P++iK + g + +G+++++++e +k+a+++  +e   a+     ++  ++++ +E +++  + + v ++ d++G+   +++++++ + ++  ++++
   EEA22818.1 194 GFPIIIKAAFGGGGRGMRVVREQESLKDAFDRATSE---AR-----SAFGNGTVFIERFLDKpKHIEVQLLGDNQGNV--VHLYERDCSVQRRHQKVV 281
                  58*****************************99977...33.....445567789*****86267899*******985..577899999999999999 PP

  ATP-grasp_4  99 yvtsa.kvieetlealeellkevnallglknfpvHiElrvsedgkiipiEvnplr 152
                   + +a ++  e  +++     ++++ ++ +n  + +E+ v+++++ + iE+np+ 
   EEA22818.1 282 ELAPAkDLPVEVRDKILADAVTLAKSVNYRNAGT-AEFLVDQQNRYYFIEINPRI 335
                  7777516888999998777777778999998765.9*****************75 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 6.4
  ATP-grasp_4   63 GeEfavdayfdeeGepvilnilkkefaseed.vsdrlyvts 102 
                   GeEf v++   e+G+ +il++l    +se+   +++ y + 
   EEA22818.1 1056 GEEFHVEL---EQGKVLILKLLAIGPLSEQTgQREVFYEMN 1093
                   77777775...678888877777666666652333334444 PP

>> ATPgrasp_ST  Sugar-transfer associated ATP-grasp
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00025      0.26      17      83 ..     153     217 ..     148     233 .. 0.79
   2 ?   -1.5   0.0       1.1   1.2e+03      10     101 ..     732     819 ..     728     835 .. 0.66

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00025
  ATPgrasp_ST  17 plvddKlkfkelalraglkvpkllgvikeqaeiseleafvkeleegvviKpakgsgGkGilvitere 83 
                    + dK+  ++la++   +vp + g+    +++++++af  e+   ++iK+a g gG+G++v+ e+e
   EEA22818.1 153 DALGDKVSARKLAIKC--NVPVVPGTPGPVEKFEDAKAFTDEYGFPIIIKAAFGGGGRGMRVVREQE 217
                  5689999999997765..555555888899*************555*****************7743 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1.1
  ATPgrasp_ST  10 yNpraefplvddKlkfkelalraglkvpkllgvikeqaeiseleafvkeleeg.vviKpakgsgGkGilviteredqdylkssgksalldele 101
                  yN  +++ ++ dK++       ++l + ++ gv+k qa    + ++ k++ ++  +   ++ s+G G++ + +  ++   +  +++ +++ + 
   EEA22818.1 732 YNL-EYYLNLVDKIVALGT---HVLGIKDMAGVLKPQAATLLIGSIRKKY-PDlPIHVHTHDSAGTGVTSMVACAQAGADAVDAATDSMSGMT 819
                  444.455666678766555...999999999*****99999999999999.664455567789999998766655555555555555555554 PP

>> DUF2118  Uncharacterized protein conserved in archaea (DUF2118)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.1   0.00016      0.17      87     131 ..    1127    1170 ..    1121    1180 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 0.00016
     DUF2118   87 pvegvkvtlivdvGdrveegdtlaavttrkgevrylrapvegvVv 131 
                  p++gv+v l v+ G +v++gd++a + + k e+  + ap +g+V+
  EEA22818.1 1127 PMSGVVVELRVHDGSEVKKGDPIAVLSAMKMEM-VISAPHHGKVA 1170
                  899*****************************7.68999999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1191 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       457  (0.0254894); expected 358.6 (0.02)
Passed bias filter:                      433  (0.0241508); expected 358.6 (0.02)
Passed Vit filter:                        55  (0.00306766); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              17  [number of targets reported over threshold]
# CPU time: 0.87u 0.29s 00:00:01.15 Elapsed: 00:00:00.47
# Mc/sec: 7656.05
//
Query:       EEA22819.1  [L=628]
Description: carboxylesterase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.9e-49  167.1   0.0      1e-48  166.5   0.0    1.1  1  COesterase     Carboxylesterase family
     0.0024   17.8   0.0        1.2    8.9   0.0    2.4  2  Abhydrolase_3  alpha/beta hydrolase fold


Domain annotation for each model (and alignments):
>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  166.5   0.0   1.1e-52     1e-48       9     441 ..     105     541 ..      96     585 .. 0.81

  Alignments for each domain:
  == domain 1  score: 166.5 bits;  conditional E-value: 1.1e-52
                 T.EEEEEEEEEESTCSEEEEEEEEESSB---GGGTTS--BE----SSEEECBS---BESEECSSSSSCGHHCHHHBES---EEEEEEESSSSSTTSSEE CS
  COesterase   9 l.GkvrGkrvklksekevdaFlGiPYAepPvgelRFkkPepaepwtgvrdAtkfspaCpqnaeksekeekeleawvsEDCLyLnvytPkekkeakkklP 106
                   G ++G++ + + ++  + F G++YA pP  ++R++ ++   p +  +  +  + +C   ae+ ++++ + +  +sEDC   nv+ P  +   +++ P
  EEA22819.1 105 SrGYIQGREIRDNADPLAQYFGGVRYALPP--SQRWAIARR-LPAEFSYGSELNPGKCDGRAETCPQPFMSDQ--GSEDCFECNVWMPVGR-CPNEGWP 197
                 359********888889*************..88*****99.5666667888888999999999999997665..9************996.677788* PP

                 EEEEE--STTTS-BGCGS-THHHHHHH..TSEEEEE----HHHHH-B-SS........TTSBS-HHHHHHHHHHHHHHHHGGGGTEEEEEEEEEEETHH CS
  COesterase 107 VlVwihGggfqtgsaseydgsaLaaeg..nvivVtinYRlGvlGFlstgd........eeapGNvGllDqvlALrWVkenIasFGGdpervtlfGesAG 195
                 V+++ihGg +qtgs ++ ++  L+ e   +++++t  YRl +lGFls ++         e  GN G++Dq++AL+W  e  + FGG+  ++t++G+sAG
  EEA22819.1 198 VIFYIHGGFLQTGSPNDTNPARLIGETnlKCVIITPVYRLAILGFLSSDElsqeaavqGEPCGNQGFWDQRTALEWAYEYAQYFGGNQYNITVAGYSAG 296
                 ************************9998899*****************444433333344459************************************ PP

                 HHHHHHHHHS....GGGTTSBSEEEEES--TTSTTTSBSHHHHHHHHHHHHTTS.-CSSHHHHHHHHHCS-HHHHHHCCGGSSSSSSTTC-SSS-B--S CS
  COesterase 196 aasvslllls....plsrglfkraIlqSGsalspwaiqkkarkrakklakkvgc.kassskelveclrsksaeelldaqekaleasssklvsfaPvvdg 289
                 + sv  +l++    p  +  +++aI+ S  +  +    ++a+k++++l  +++  +   ++e +  lr+ ++++l+d+         +++++  P  dg
  EEA22819.1 297 SFSVFNQLAHdlylPREKSIIRQAIMLSNGPGVQPKAASEAQKQFDQLLIALNIpTHLPASEKLARLRRIPTRQLIDTSLR------TQYHQYRPWHDG 389
                 ****888765333478889*********777777777888**************44445559999**************88......788999999999 PP

                 SSSSS-HHHHHHCGC........CSEEEEEEETTTTHHHHCCHSTTTSSSSHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHS.TTTSSTCHHHHHH CS
  COesterase 290 dflpekPeellkseg........kvplliGvnkdegllflaylldkeksvkkkeeklsesllkdelyleaekkeelseaikeeyt.deadrddaeksrk 379
                 +f+p +  + + + +        ++ l+ G  +de  l  + ++++ +s+ + +++l+++            ++++ +++ + y  d +  +   ++++
  EEA22819.1 390 QFVPTTLFSDIDNGTfarrmverNIRLINGECRDEHFLYGTWYTPA-NSLGSLRQRLEADY-----------PSDACDTLVNLYYpDGQLPAGVYNWQD 476
                 9999777766666446666788899999999999987777755554.45555555544333...........6677777777777366667888899** PP

                 HHHHHHHHHHTHHHHHHHHHHHHHTT-S..EEEEEEE--STTSSSTTTGSSBTTTTHHHHT.TGG CS
  COesterase 380 allelltdvlfkapvlrtaklhasrgsp..vYlYsfdyrnssskkpkwmgvvhgdeleyvf.glp 441
                 a+ +l+ dv++++  + +++++a+ g+   vY Y+ +yr +    p+  gv+h++++ +++ g+ 
  EEA22819.1 477 AFGRLYADVQVHMLERGFVNALAQGGAGhlVYRYRIEYRVECVTLPPEWGVTHSSDMAMWLwGNG 541
                 **********************97777777**********999999999*******987540443 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.4   0.0   0.00082       7.4       1      40 [.     199     238 ..     199     239 .. 0.83
   2 !    8.9   0.0   0.00014       1.2      50      82 ..     265     297 ..     261     351 .. 0.66

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.00082
                    EEEE--STTTS--TTTTHHHHHHHHHHHTSEEEEEE---T CS
  Abhydrolase_3   1 lvyfHGGGfvlgsldthdalcrelakelgavvvsvdYrlA 40 
                    ++y+HGG   +gs++  ++       +l++v++ + YrlA
     EEA22819.1 199 IFYIHGGFLQTGSPNDTNPARLIGETNLKCVIITPVYRLA 238
                    68*****999999988755555556789***********9 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.00014
                    HHHHHHHHHHHHTHHHHTETTCEEEEEEETHHH CS
  Abhydrolase_3  50 edalaalrwlaeqawelgadpsrivlaGdSaGG 82 
                     d  +al+w+ e a+ +g ++ +i++aG SaG 
     EEA22819.1 265 WDQRTALEWAYEYAQYFGGNQYNITVAGYSAGS 297
                    57889********99*****************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (628 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       559  (0.0311785); expected 358.6 (0.02)
Passed bias filter:                      523  (0.0291706); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.30s 00:00:00.95 Elapsed: 00:00:00.47
# Mc/sec: 3988.27
//
Query:       EEA22820.1  [L=119]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
     0.0038   17.8   4.7     0.0077   16.8   4.7    1.5  1  Caskin1-CID  Caskin1 CASK-interaction domain
  ------ inclusion threshold ------
      0.086   12.9   3.4       0.11   12.6   2.7    1.5  1  DUF4716      Domain of unknown function (DUF4716)


Domain annotation for each model (and alignments):
>> Caskin1-CID  Caskin1 CASK-interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   4.7   8.6e-07    0.0077      15      46 ..      52      83 ..      47      86 .. 0.89

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 8.6e-07
  Caskin1-CID 15 RSsvgStgsvasaRssgsgqssghaLHagaeG 46
                 R s +Stgs +s Rssgsg++  ++L ++  G
   EEA22820.1 52 RDSESSTGSTGSRRSSGSGKTLFETLNSQKRG 83
                 7899****************999999988766 PP

>> DUF4716  Domain of unknown function (DUF4716)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   2.7   1.2e-05      0.11      20      46 ..      40      66 ..      32      74 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.2e-05
     DUF4716 20 CaWslWPsiterrdtedWtlgtGlrre 46
                 +Ws W +  +rrd e  t  tG rr 
  EEA22820.1 40 APWSGWDADKKRRDSESSTGSTGSRRS 66
                69*****************99****97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (119 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       510  (0.0284455); expected 358.6 (0.02)
Passed bias filter:                      298  (0.0166211); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.33u 0.26s 00:00:00.59 Elapsed: 00:00:00.38
# Mc/sec: 937.50
//
Query:       EEA22821.1  [L=175]
Description: 60S ribosomal protein L11 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.8e-22   78.7   0.0    4.1e-22   78.1   0.0    1.3  1  Ribosomal_L5_C  ribosomal L5P family C-terminus
    2.4e-20   72.6   0.0    7.4e-20   71.0   0.0    1.8  2  Ribosomal_L5    Ribosomal protein L5
  ------ inclusion threshold ------
      0.051   13.3   0.0        0.1   12.3   0.0    1.4  1  HTH_ABP1_N      Fission yeast centromere protein N-terminal d


Domain annotation for each model (and alignments):
>> Ribosomal_L5_C  ribosomal L5P family C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.1   0.0   6.9e-26   4.1e-22       1      94 []      67     165 ..      67     165 .. 0.87

  Alignments for each domain:
  == domain 1  score: 78.1 bits;  conditional E-value: 6.9e-26
  Ribosomal_L5_C   1 piGvkvtLrgekmyefldkllevvlprlrdFkGiskssfdgrGnvsfGikeqiifpeieydkdkgifGmditivttaktde.............e 82 
                     +i+v+vt+rg+k++e+l++ l+v++++lr      k++f+++Gn++fGi+e+i++ +i+yd+ +gi+Gmd+++++t++ ++             +
      EEA22821.1  67 KIAVHVTVRGPKAEEILERGLKVKEYELR------KRNFSETGNFGFGISEHIDL-GIKYDPGIGIYGMDFYCCMTRPGERiakrrrakahigsN 154
                     69***************************......********************.**********************44444456677777755 PP

  Ribosomal_L5_C  83 arallkelgipf 94 
                     ++ ++++++i++
      EEA22821.1 155 HK-ITQGETIKW 165
                     55.777777765 PP

>> Ribosomal_L5  Ribosomal protein L5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.0   0.0   1.2e-23   7.4e-20       1      57 []      10      63 ..      10      63 .. 1.00
   2 ?   -1.9   0.0      0.76   4.5e+03       9      18 ..      66      75 ..      66      87 .. 0.73

  Alignments for each domain:
  == domain 1  score: 71.0 bits;  conditional E-value: 1.2e-23
                  SCTTS-EEEEEEEEEE-SSSSSCHHHHHCCHHHHCCCHSS--EECC--TTCTTTCSC CS
  Ribosomal_L5  1 NvMqvPrleKivinmgvGeagedkkllekaakeLaeItGQkPvvtkakksianFkiR 57
                  N+M++ r++K+v+n+ vGe+g++   l++aak+L++++GQ+Pv +ka++++++F+iR
    EEA22821.1 10 NPMRELRIQKLVLNISVGESGDR---LTRAAKVLEQLSGQTPVYSKARYTVRTFGIR 63
                  9**********************...******************************9 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.76
                  EEEEEEEE-S CS
  Ribosomal_L5  9 eKivinmgvG 18
                  eKi +++ v 
    EEA22821.1 66 EKIAVHVTVR 75
                  7999998885 PP

>> HTH_ABP1_N  Fission yeast centromere protein N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   1.7e-05       0.1      16      38 ..     149     171 ..     138     173 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.7e-05
  HTH_ABP1_N  16 wafqqnprpsqkaliaWFeqeyg 38 
                  ++  n++ +q + i+WF+++++
  EEA22821.1 149 AHIGSNHKITQGETIKWFKNRFE 171
                 456789***************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (175 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       348  (0.0194099); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.59u 0.36s 00:00:00.95 Elapsed: 00:00:00.58
# Mc/sec: 911.99
//
Query:       EEA22822.1  [L=202]
Description: small nuclear ribonucleoprotein SmB, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.3e-20   70.6   0.0    7.6e-20   70.4   0.0    1.1  1  LSM       LSM domain


Domain annotation for each model (and alignments):
>> LSM  LSM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   70.4   0.0   4.2e-24   7.6e-20       3      66 ..       9      90 ..       7      91 .. 0.97

  Alignments for each domain:
  == domain 1  score: 70.4 bits;  conditional E-value: 4.2e-24
                HHHTTTSEEEEEETTSEEEEEEEEEEETTSEEEEEEEEEEETTET..................EEEEEEEEEEEGGGEEEEE CS
         LSM  3 lkklinkkvtvelkngrelrGtLkgfDqfmNlvLedveetlkdkk..................ekrklglvliRGnnivlis 66
                +++lin++++v l++gr+  G++ +fD++mNlvL d+ee+++ k+                  ekr lgl+++RG+n+v+ s
  EEA22822.1  9 MQNLINYRMRVTLNDGRQMTGQMLAFDKHMNLVLADTEEFRRVKRkaakqapgaaaaplveaeEKRTLGLTIVRGTNVVSCS 90
                89****************************************************************************9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (202 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       395  (0.0220313); expected 358.6 (0.02)
Passed bias filter:                      302  (0.0168442); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.33s 00:00:00.93 Elapsed: 00:00:00.54
# Mc/sec: 1120.41
//
Query:       EEA22823.1  [L=124]
Description: UPF0041 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-35  122.1   0.0    1.2e-35  121.9   0.0    1.0  1  MPC       Mitochondrial pyruvate carriers


Domain annotation for each model (and alignments):
>> MPC  Mitochondrial pyruvate carriers
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.9   0.0   6.9e-40   1.2e-35       5     108 ..      12     117 ..       8     119 .. 0.92

  Alignments for each domain:
  == domain 1  score: 121.9 bits;  conditional E-value: 6.9e-40
         MPC   5 flnsetgkk..tvhFWaPvlkwglviaglsDlkrpaekiSltqnlaLlatgliwtryslvikPkNyllaavnfvlelvglvqvsRilkyrlskkdekke 101
                 + +++++++  ++hFW+P++++g++ia+++D+++++e iS++++ aL+++++ ++rysl+++PkNyll+a+++++++ + +q++R+l+y++  ++ek+ 
  EEA22823.1  12 IRSNKVLDYvcSTHFWGPASNFGIPIAAVMDIQKDPEIISGPMTGALVVYSATFMRYSLAVSPKNYLLFACHAINFTSQSIQGYRYLNYWNWGGREKAL 110
                 556777888889*******************************************************************************99999888 PP

         MPC 102 akkeike 108
                 a+k ++e
  EEA22823.1 111 AEKGVQE 117
                 7777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (124 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       359  (0.0200234); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.32s 00:00:00.88 Elapsed: 00:00:00.54
# Mc/sec: 694.65
//
Query:       EEA22824.1  [L=756]
Description: amino acid transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.9e-84  281.7  32.5    9.8e-84  281.4  32.5    1.0  1  Aa_trans  Transmembrane amino acid transporter protein


Domain annotation for each model (and alignments):
>> Aa_trans  Transmembrane amino acid transporter protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  281.4  32.5   5.4e-88   9.8e-84       4     408 ..     357     738 ..     354     739 .. 0.94

  Alignments for each domain:
  == domain 1  score: 281.4 bits;  conditional E-value: 5.4e-88
    Aa_trans   4 salsavlnlikaivGaGvLaLPyAfkqlGlivGlillllvallslytlllLvkcsktlasgkrnksYgdlgyrllGpkgkliidlailvqlfGvgvsyl 102
                 + + a+l l+k++vG+GvL+LP Af ++G++++ i+ll+v+l+s+y++ lLv+ + +        s+gd+g  l+G++++ ii  +i+++++G++ +y+
  EEA22824.1 357 TSMGAALLLLKSFVGTGVLFLPRAFLNGGMLFSSIVLLVVSLVSYYCFILLVNSRLK-----IEGSFGDIGGVLYGKWMRRIILGSIVLSQLGFVAAYI 450
                 56678999**********************************************985.....569********************************** PP

    Aa_trans 103 iligdllpaifesffdt.lllsnvyfilisaliiipLslipnlskLsylSllalvsslyyivilvlvvaelvklelkgvseetvkkasklkglflaigi 200
                 ++++++l+a++  +++  + ++  y++l++ ++++pLsli+++skL++++l+a+v+++++++ l+++ ++ +  ++kgvs+  +   ++  +++l+ig+
  EEA22824.1 451 VFTSQNLQAFILAVSKClTYIDIKYMVLMQLIVFLPLSLIRDISKLGFTALIADVFIMLGLIYLYYYDFSTI-IDQKGVSDIVA---FNPNSWTLFIGT 545
                 ************987777888*************************************99888888888765.56778888876...7777******** PP

    Aa_trans 201 ivFAftghavlleiqnelkdpskfkkmtkvlllsiilatvlyilvGlvGYltFGnevkgnillnlpkssilivivnlllvlhlilsfplqlhplrqvve 299
                 ++F+++g  ++++iq+++k+p+kf+    vl +++il+tv+++++G v Y+++G+++k+++llnlp+ + + ++v++l+ l+++ls+plql+p++++ e
  EEA22824.1 546 AIFTYEGVGLIIPIQESMKQPKKFP---GVLATVMILITVVFLSAGAVSYAAYGSATKTVVLLNLPQDDKFVNAVQFLYSLAILLSTPLQLFPAIRICE 641
                 *************************...9********************************************************************** PP

    Aa_trans 300 nllikkeavagasekeapkskllrlvirlllvvityliA.lsvpslakvlslvGatsstplsfilPalfhlkliktekksleklvkkkildlicivlgl 397
                 n l+++      s+k +p +k+ ++++r++lv++  ++A   +  l+k++slvG+++++pl++++P+l+hlk++ t+   +++      +d+  +v+g+
  EEA22824.1 642 NELFTR------SGKYNPGIKWKKNFFRFMLVMFCAFVAwGGAGDLDKFVSLVGSFACVPLVYVYPPLLHLKACATTR--FQRS-----ADIGLAVVGV 727
                 ****98......***************************8899*********************************95..4444.....5899****** PP

    Aa_trans 398 llvfyglavli 408
                 ++++y+++ +i
  EEA22824.1 728 ICCIYTTTLTI 738
                 *****998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (756 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       628  (0.0350271); expected 358.6 (0.02)
Passed bias filter:                      298  (0.0166211); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.79u 0.34s 00:00:01.13 Elapsed: 00:00:00.56
# Mc/sec: 4048.38
//
Query:       EEA22825.1  [L=1299]
Description: cation chloride cotransporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    2.8e-58  197.7  37.6    3.5e-58  197.4  37.6    1.1  1  AA_permease  Amino acid permease
    8.9e-20   71.1   3.8    1.4e-07   31.0   0.0    3.5  4  SLC12        Solute carrier family 12


Domain annotation for each model (and alignments):
>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  197.4  37.6     4e-62   3.5e-58       1     478 [.     137     615 ..     137     616 .. 0.89

  Alignments for each domain:
  == domain 1  score: 197.4 bits;  conditional E-value: 4e-62
  AA_permease   1 hvlvialggviGtglfvglgvvlsqaGplgallayllagvviflvmlslgeiatngp.ksggfytyasrflgpelGfviGln.ylfswitvlalelta 96 
                  +v+v + ++v ++ +f++ g+vl+q G+ g++ +++ ++++ +l+++s+++iatng  ++gg+y+++sr+lgpe+G++iG+  y+ + + + +++l+ 
   EEA22825.1 137 GVFVPTSLNVLSILMFLRFGFVLGQSGVFGMMGMLVASYIIDLLTTMSISAIATNGTvRGGGAYYLISRSLGPEFGGSIGIVfYMGLIFNTGMNALGL 234
                  57888899**************************************************************************5555555567777777 PP

  AA_permease  97 asiliqfwelvtdlpkawvt.........gavflvvlliinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkgagfrflgdngsifknn 185
                  ++ ++++ +  +  ++ +           g+++l+v ++i+++g   +++a+  l+ i++i+  +  +   i +    ++++ g++f+g+++ +f +n
   EEA22825.1 235 VNCIVENFGVESGSWSNFLQegfwwnylwGSIVLLVCTAICFAGSSIFARASNGLLAILLISTFSIPLSALIQH--PFKSPELGVEFTGFSMKTFLEN 330
                  777777776655444444447778999**************************999999988877666663333..2333333677888888888888 PP

  AA_permease 186 lppgfa.keeegaf...knfisvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasaaspfvif 279
                  l p  + + +++++    nf  +f i+++a +Gi ++a+++g++k+P++siP ++l+ ++++++ Y+ +++++ + + r++             ++++
   EEA22825.1 331 LKPHLTkGAAGSQLahrENFQDLFGILFPATSGIFAGANMSGDLKNPSRSIPTGTLSGLLLTFFTYTVVIFSMAASITRQS------------FYNNV 416
                  8887774444443322269********************************************************999987............56677 PP

  AA_permease 280 ikesgvsvlaplinaviltaalssansslysasRvlyslakdglaP...kvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisal 374
                   +    +v ++l+ ++ ++a ++s++s+l+ + ++l++ ++d+l P    ++k ++k+  P+ ail+s++++++ +l +  + a ++++++l+++ a 
   EEA22825.1 417 NVIQVTNVSGTLVLLGEFAASFFSSLSGLIGSAKLLQAISRDNLVPglaIFGKASNKNDDPILAILFSFVVAQITMLFDINKIASFTAMTYLMTFLA- 513
                  78889999****************************************999999***********************99999999999999999986. PP

  AA_permease 375 iglivwlliilsylrfRkalkyqgrsieelgfkaallplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfliilvgvklhvkn 472
                  i+l+++ll i s ++fR++++y ++ ++ lg+   l++++++ ++ a   i+++ +l+ ++ +  +pk+wg +s+ + y++v  +l++l+    hvk+
   EEA22825.1 514 INLACFLLKIGSAPNFRPSFRYFNWVTAALGAVFSLASMFFVDGVYATGCIVVLIFLFVLIHYTSPPKSWGDVSQSLIYHQVRKYLLRLKQ--EHVKF 609
                  7***************************************************************************************986..68999 PP

  AA_permease 473 krpqll 478
                  +rpq+l
   EEA22825.1 610 WRPQIL 615
                  999986 PP

>> SLC12  Solute carrier family 12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.0   0.0   1.5e-11   1.4e-07       4      84 ..     627     709 ..     625     716 .. 0.86
   2 !   13.1   0.0   4.1e-06     0.037     253     308 ..     826     882 ..     821     886 .. 0.89
   3 ?   -4.3   0.5      0.74   6.7e+03     146     146 ..    1030    1030 ..     977    1100 .. 0.43
   4 !   26.1   0.0   4.4e-10     4e-06     365     424 ..    1232    1295 ..    1229    1297 .. 0.91

  Alignments for each domain:
  == domain 1  score: 31.0 bits;  conditional E-value: 1.5e-11
       SLC12   4 LvdlahlitknvsLlicghvvkeklsqklreel...tkkaqkwLkkrkikaFyalvdaesleegakaLlqasGlgklkpnilll 84 
                 +v++++++ k+ +L++ ghv+ ++  +++  e    +   +k+++  k+kaF +++ a + e g+++++  sGlg ++pni+++
  EEA22825.1 627 MVHFCNSL-KKGALFVLGHVIVTDDFTNAVPEArrrQAAWTKFIEYSKVKAFTNITVAPTAEWGVRNIVLNSGLGGMRPNIVII 709
                 899**999.5679*******99887666554543557777889999************************************97 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 4.1e-06
       SLC12 253 DDGgLtlllpyilstrkkw.kecklRvFalankkeeleeeqremaslLskfridysd 308
                 D   L+l l  il+t  +w k+ +lRv +  + ++++eee+ ++++lL+k+ri+ + 
  EEA22825.1 826 DTYTLILQLGCILNTVPSWkKSYNLRVAVFVEYESDVEEERGRVSALLEKLRIKAQV 882
                 5567999999*********66679***99999999******************9765 PP

  == domain 3  score: -4.3 bits;  conditional E-value: 0.74
       SLC12  146 e 146 
                  e
  EEA22825.1 1030 E 1030
                  0 PP

  == domain 4  score: 26.1 bits;  conditional E-value: 4.4e-10
       SLC12  365 rqlrlrElLkehSskanLivmsLPvprkgav....saalYmaWLevLtkdlpPvlLvRGnqtsv 424 
                  ++l l+El+ ++S +++++  +LP p  g++    ++  Y++ +evL ++lpP+lLv  n  +v
  EEA22825.1 1232 QHLILNELITRQSAETAVMFTTLPSPVEGTCldnaASEAYVSDIEVLCRGLPPCLLVHSNSMTV 1295
                  6899*************************9855556789*******************998877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1299 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       899  (0.0501422); expected 358.6 (0.02)
Passed bias filter:                      443  (0.0247086); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.92u 0.30s 00:00:01.22 Elapsed: 00:00:00.48
# Mc/sec: 8167.61
//
Query:       EEA22826.1  [L=558]
Description: mevalonate kinase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.9e-16   59.5   1.4    2.5e-15   56.5   0.0    2.5  2  GHMP_kinases_N   GHMP kinases N terminal domain
    4.8e-08   33.2   0.0    1.3e-07   31.9   0.0    1.7  1  GHMP_kinases_C   GHMP kinases C terminal
    0.00044   19.7   0.0     0.0011   18.4   0.0    1.7  1  GalKase_gal_bdg  Galactokinase galactose-binding signature
  ------ inclusion threshold ------
       0.24   12.2   1.3       0.56   11.0   1.3    1.6  1  Clr2             Transcription-silencing protein Clr2
        1.2    9.9  14.2        3.2    8.5  14.2    1.7  1  MAGE_N           Melanoma associated antigen family N termina
        3.5    8.1   7.2        6.6    7.2   7.2    1.4  1  MGC-24           Multi-glycosylated core protein 24 (MGC-24),


Domain annotation for each model (and alignments):
>> GHMP_kinases_N  GHMP kinases N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.3      0.16   4.9e+02      15      32 ..      77      94 ..      77     113 .. 0.82
   2 !   56.5   0.0   8.3e-19   2.5e-15       3      65 ..     246     323 ..     245     324 .. 0.78

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.16
                    CHHHHHHHHHHHHHHHHT CS
  GHMP_kinases_N 15 GSSAAlavalvaAllall 32
                    +SS+A ++a++   +++ 
      EEA22826.1 77 SSSSATSTATAQTTAKMS 94
                    699999999998777765 PP

  == domain 2  score: 56.5 bits;  conditional E-value: 8.3e-19
                     EEEESSHTTSSSCHHHHHHHHHHHHHHHHTT...........EHHHH........HHHHHHHHHHHHHHHHHSHHHHHHHHS CS
  GHMP_kinases_N   3 vikseiPvgaGLGSSAAlavalvaAllallg...........lslee........aklaleaerlaqggngsggDvaasvyG 65 
                     +++s+iP+gaGLGSSA+++v+l aAll                   e        +++a+++e +++ gn+sg+D+++s+ G
      EEA22826.1 246 TLRSTIPIGAGLGSSASVSVCLSAALLLQIRtlagphpdqppE---EaevqieriNRWAFVGEMCIH-GNPSGVDNTVSAGG 323
                     689**********************955442333354444330...155566679************.*********99865 PP

>> GHMP_kinases_C  GHMP kinases C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.9   0.0   4.3e-11   1.3e-07       9      74 ..     408     474 ..     400     486 .. 0.82

  Alignments for each domain:
  == domain 1  score: 31.9 bits;  conditional E-value: 4.3e-11
  GHMP_kinases_C   9 dlellgellnlsqrselkavvgilppeleellealselGalgaklsGaGgGptvfalf...kdkdeaeq 74 
                      le++g l + ++   l+  +g+++p+le++ e+   + +   kl+GaGgG++ ++l+    +++  ++
      EEA22826.1 408 ALEEFGALFRINHG--LLVSLGVSHPRLERIRELVDYANIGWTKLTGAGGGGCAITLIrpdATPETLKD 474
                     4699**********..8******************88889******************55544444444 PP

>> GalKase_gal_bdg  Galactokinase galactose-binding signature
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.0   3.8e-07    0.0011      11      47 ..     108     145 ..     101     147 .. 0.90

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 3.8e-07
                      -.EEEEEEEEEEEE--S-TTTT-EEEEEEEEEEEEEEE CS
  GalKase_gal_bdg  11 p.fvasAPGRvnLiGEHtDYngGfVlpmAieqdiyiav 47 
                      p f++sAPG v + GEH   +g   l++Ai ++ y+ v
       EEA22826.1 108 PaFMVSAPGKVIVFGEHAVVHGKAALAAAISLRSYLLV 145
                      3599****************************999887 PP

>> Clr2  Transcription-silencing protein Clr2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   1.3   0.00019      0.56      28     136 ..       8     122 ..       2     129 .. 0.60

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00019
        Clr2  28 nlasklelssdasndkadvlvideIqvllktadeedleeketirlaGkvytlvrkraykp........pssnaappakpkpleavvieelpkgfkavel 118
                 +++++ +  ++ s+++ + l   ++++++++ ++    e++  ++ G++ t+ ++++++         p+sn++++a  ++    +++  +++ + +++
  EEA22826.1   8 KKHGSVKRTHTSSKKQQLTLSELQSRFEIQNNISG---ESTDSSVDGTILTPTSTSTPDSvsnaqttpPTSNSSSSA-TSTA---TAQT-TAKMSRTQM 98 
                 45677778888888889999999999888777777...999****************98875554432222222211.1111...2222.222222222 PP

        Clr2 119 ....rkygewyrvh..sgkevels 136
                     +  +++ +++  +gk ++  
  EEA22826.1  99 krkqSSPMAPAFMVsaPGKVIVFG 122
                 333344555555554555555555 PP

>> MAGE_N  Melanoma associated antigen family N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5  14.2    0.0011       3.2       3      78 ..      15      95 ..       8     107 .. 0.74

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.0011
      MAGE_N  3 sklrarEkrrqaraetqglegaQataaeeeestsss......splsedtpessp.aagtpsapqspqgapssttaaaavsrtr 78
                + + + +k++ + +e q+  + Q   +   est ss      +p s +tp s++ a+ tp ++ s+ +a s++ta +++  +r
  EEA22826.1 15 RTHTSSKKQQLTLSELQSRFEIQNNIS--GESTDSSvdgtilTPTSTSTPDSVSnAQTTPPTSNSSSSATSTATAQTTAKMSR 95
                455566666667788888777777777..4455666699999************88889999999999999999877554444 PP

>> MGC-24  Multi-glycosylated core protein 24 (MGC-24), sialomucin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.2   7.2    0.0022       6.6      50     122 ..      52     126 ..      15     128 .. 0.54

  Alignments for each domain:
  == domain 1  score: 7.2 bits;  conditional E-value: 0.0022
      MGC-24  50 elcsaaskstpkptnstaktttkpsstttstsvatsgttnttvtptsqparkst.FDaAsFi...GGivLvLgvqAv 122
                 ++ + +s+stp +++++ +t   p+s ++s++++t+++ +t+ +  +q +rk++   a +F+    G v+v g  Av
  EEA22826.1  52 TILTPTSTSTPDSVSNAQTT--PPTSNSSSSATSTATAQTTAKMSRTQMKRKQSsPMAPAFMvsaPGKVIVFGEHAV 126
                 33444455555555333333..2333333333345555556666666666665403344454222366666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (558 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1042  (0.0581181); expected 358.6 (0.02)
Passed bias filter:                      589  (0.0328518); expected 358.6 (0.02)
Passed Vit filter:                        74  (0.00412739); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.68u 0.32s 00:00:01.00 Elapsed: 00:00:00.48
# Mc/sec: 3503.42
//
Query:       EEA22827.1  [L=692]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.5e-30  106.3   1.1    1.3e-20   73.6   0.4    2.2  2  Fungal_trans_2  Fungal specific transcription factor domain
    3.2e-07   30.4   9.5      5e-07   29.7   9.5    1.3  1  Zn_clus         Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Fungal_trans_2  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.6   0.4   1.4e-24   1.3e-20       2     285 ..     222     502 ..     221     515 .. 0.89
   2 !   31.2   0.0   1.1e-11   9.5e-08     327     383 ..     634     691 ..     575     692 .] 0.93

  Alignments for each domain:
  == domain 1  score: 73.6 bits;  conditional E-value: 1.4e-24
  Fungal_trans_2   2 lldyyldnvapllspvpessnpfrkvllplalsnkallhallalsafhlqskgpkdslereakrykslalkelqealaelsstlsrnekykdiLa 96 
                     l +yy+++va l+s ++++ npfr+++  l  s++a + +l +++a+ l          ++  ++   +lk+++ea+  l+s+++   +++  L 
      EEA22827.1 222 LVEYYFKEVAGLFSSYDSHMNPFRTTVSRLWASSPAMCRTLQSMAAATL---------VDDFPQFGPVGLKMRKEAILLLESQET---HDDKSLL 304
                     679**********************************************.........7788999********************...8899999 PP

  Fungal_trans_2  97 aiLllcsieissgdvsdwrv.hLeaatsliksrggs..kasssslsskarfllrifayldilssttlgrgpsfpseeyekllenkkeesdsgldp 188
                     a+L+l     s++++ d ++ +++  ++ ++s+     + s  ++++  +f+ + ++y+++l s+  +++++ +s        n++ +++   +p
      EEA22827.1 305 AMLMLGQT-ASWHNPNDLGIsYFNTLRNHLNSLTSGinSGSLLTNRNNYQFFEEALIYWEMLLSFVADTSTLNSSAKVHLAAANDQPLTQKVPHP 398
                     97777777.9****99977778888888888888877666666888899*******************666666666666666677778888999 PP

  Fungal_trans_2 189 lmGcsnslilliseisrLarekrsarkd.......seleplsileeaseleqrll.swkprssdlepdldeterasslskdltelfrlaaliyly 275
                     ++G+ +    + ++++rL+r+ r++          ++++ ++  +ea ele+rll   +p ++d   + d++ + ++l   ++e++r++ l+ ly
      EEA22827.1 399 WTGIARDTQFIVNKVGRLVRRERKRIRAkrftsqrDITQAQEAIREALELEERLLsLAHPAETDVVNPGDNDTPVWHLL-AMAEVYRHTGLLQLY 492
                     *******************9988888888999999999999**************9999*******************9.99************* PP

  Fungal_trans_2 276 rlvlglppss 285
                     r++++l ++ 
      EEA22827.1 493 RVFPDLLRDR 502
                     ***9998774 PP

  == domain 2  score: 31.2 bits;  conditional E-value: 1.1e-11
  Fungal_trans_2 327 ddRdfvrrrleeleqsrl..gnvrrarqvleevWrrrddgeekidWrdvmekkgwelll 383
                       R+f++ rl ++  + l  + +r + ++++evW+r+d ge+ + W+dvm +kgwe+++
      EEA22827.1 634 RTRKFILGRLTSFL-HVLppKPIRICVDLVQEVWQRMDAGESDVYWMDVMIDKGWETTM 691
                     47************.999*************************************9875 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.7   9.5   5.5e-11     5e-07       2      38 ..      10      46 ..       9      48 .. 0.94

  Alignments for each domain:
  == domain 1  score: 29.7 bits;  conditional E-value: 5.5e-11
                S-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCC CS
     Zn_clus  2 aCdnCrkkKvKCdakkPaCsnCkklnleCtfysessk 38
                +C +C++k+ KCd+ +PaC++C +l+ +C  y+++ +
  EEA22827.1 10 GCATCKSKRLKCDESRPACGRCTRLRIKCPGYTQRFR 46
                7*****************************9999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (692 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       408  (0.0227564); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.42
# Mc/sec: 5000.93
//
Query:       EEA22828.1  [L=60]
Description: hypothetical protein PMAA_094360 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (60 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       179  (0.00998383); expected 358.6 (0.02)
Passed bias filter:                      158  (0.00881254); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.29s 00:00:00.67 Elapsed: 00:00:00.45
# Mc/sec: 399.84
//
Query:       EEA22829.1  [L=737]
Description: sulfatase domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.2e-20   74.2   0.3    1.9e-20   73.5   0.3    1.2  1  Sulfatase     Sulfatase
    9.6e-07   28.7   0.0    1.9e-06   27.7   0.0    1.5  1  Phosphodiest  Type I phosphodiesterase / nucleotide pyrophosp
    2.7e-05   23.0   0.0    5.6e-05   21.9   0.0    1.5  1  DUF229        Protein of unknown function (DUF229)
  ------ inclusion threshold ------
      0.058   13.5   0.0       0.13   12.4   0.0    1.6  1  DUF4287       Domain of unknown function (DUF4287)


Domain annotation for each model (and alignments):
>> Sulfatase  Sulfatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.5   0.3   4.3e-24   1.9e-20      95     307 ..     398     603 ..     391     605 .. 0.79

  Alignments for each domain:
  == domain 1  score: 73.5 bits;  conditional E-value: 4.3e-24
                 EEEEEEES-SCCSGGGSHHCCTTTSEEEETSSSCHHTCCCCCCCCCECTCCCTTTTCSHHHHHHHHHHHHH..HCCCTSSEEEEEEE-TTSSST..... CS
   Sulfatase  95 ntaaigkwhlgwssrqsvyknrgfdrflgfptgsaalkdpekseyngevlrvppeggysddrlldealefl..larndkpfflylatlapHapp..... 186
                 ++ +++  +  ++++ +  ++ gfd+ +   +++++ ++++ ++        ++  gy   +++ ++ + +  +++n++  fl   t+ +H+p+     
  EEA22829.1 398 RSVFMQSITGEFDNQRKLNEQMGFDQSIFKENINSRSAKHWHEGMKE-----INYFGYEEPEIYPYLKDTIeeAKANGERLFLSHFTSTTHHPWglpse 491
                 5556666666777777777799****777566666666655444443.....5677899999*********955555***************9955455 PP

                 .CTCGGHTCCGSTTTTCCCCCCH.....HHHHHHHHHHHHHHHHHHHHHHHHHHTTTGGGEEEEEEESSSSCCCGHHTTSSSCTTCSSSHHHHBEEEEE CS
   Sulfatase 187 .eapdeyakkyatffddgseaar.....qlleaylnsveyvDdligrvlaaLeenglldntlvvftSDhgasleesngplrggkganayeggtrvPllv 279
                  +++d ++ +            r     q  ++yln+v+yvD+ +g+v++ +ee+g +++tlvvf++Dhg++  e    + +g  +n + + +rvPl+ 
  EEA22829.1 492 iQVEDYWPHN------------RfssehQPSNKYLNTVHYVDKWLGNVMQIIEEAGIANETLVVFVGDHGQAFAE--DSHIIGTFENGHISNFRVPLVF 576
                 5555555554............1222339********************************************55..56666777799*********** PP

                 EETTTSHCEEECSEEEGGGHHHHHHHHT CS
   Sulfatase 280 wwpgekaprvseelvshiDlfptildla 307
                 + p   +   +++ +s++ ++ptildl+
  EEA22829.1 577 RHPLLPRL-EVHANASSMSILPTILDLL 603
                 ***99999.9****************96 PP

>> Phosphodiest  Type I phosphodiesterase / nucleotide pyrophosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.7   0.0   4.2e-10   1.9e-06     194     241 ..     510     557 ..     449     598 .. 0.87

  Alignments for each domain:
  == domain 1  score: 27.7 bits;  conditional E-value: 4.2e-10
                   SHHHHHHHHHHHHHHHHHHHHHHHTTGTTTEEEEEEES---EEEHTTS CS
  Phosphodiest 194 spevedalrrvDkaigdLlealderglsaetniilvSDHGmadvsddk 241
                   s + ++++++vDk++g+ ++ ++e g+++et ++ v+DHG+a   d++
    EEA22829.1 510 SNKYLNTVHYVDKWLGNVMQIIEEAGIANETLVVFVGDHGQAFAEDSH 557
                   556999***********************************9986544 PP

>> DUF229  Protein of unknown function (DUF229)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.9   0.0   1.2e-08   5.6e-05     294     348 ..     500     554 ..     493     642 .. 0.82

  Alignments for each domain:
  == domain 1  score: 21.9 bits;  conditional E-value: 1.2e-08
      DUF229 294 lfgffwsnslshdkfnllealDedllkylkklekkgllentlvlllsDHGlrfgk 348
                 + +f +  ++s +++n +  +D+ l ++++ +e+ g+ ++tlv++++DHG  f++
  EEA22829.1 500 HNRFSSEHQPSNKYLNTVHYVDKWLGNVMQIIEEAGIANETLVVFVGDHGQAFAE 554
                 5689999*******************************************98876 PP

>> DUF4287  Domain of unknown function (DUF4287)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0     3e-05      0.13       2      26 ..     696     720 ..     695     724 .. 0.92

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 3e-05
     DUF4287   2 fqsyldniekkTGktldewlalade 26 
                 f+s+l ++++k+G ++++wl+ a++
  EEA22829.1 696 FHSLLHTVKRKYGNDAAHWLSEAEK 720
                 789******************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (737 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       513  (0.0286129); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.44
# Mc/sec: 5029.72
//
Query:       EEA22830.1  [L=350]
Description: CaaX farnesyltransferase alpha subunit Ram2 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.4e-37  126.3  14.4    1.2e-08   34.3   0.6    5.4  5  PPTA      Protein prenyltransferase alpha subunit repeat


Domain annotation for each model (and alignments):
>> PPTA  Protein prenyltransferase alpha subunit repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.6   0.0     9e-11   1.6e-06       2      27 ..      63      88 ..      62      89 .. 0.93
   2 !   27.9   1.9   7.6e-11   1.4e-06       1      27 [.      97     123 ..      97     124 .. 0.96
   3 !   34.3   0.6     7e-13   1.2e-08       3      28 .]     137     162 ..     137     162 .. 0.94
   4 !   22.4   0.1   3.8e-09   6.9e-05       5      24 ..     175     194 ..     171     195 .. 0.86
   5 !   19.2   0.0   3.9e-08    0.0007       1      27 [.     232     258 ..     232     259 .. 0.97

  Alignments for each domain:
  == domain 1  score: 27.6 bits;  conditional E-value: 9e-11
                HHHHHHHHHH-TT-CHHHHHHHHHHC CS
        PPTA  2 LeltekliekdpkNYsaWnyRrwlle 27
                L+lte++i ++p +Y++W yR  +l 
  EEA22830.1 63 LQLTEDVIMMNPAHYTVWLYRAKILF 88
                9********************98885 PP

  == domain 2  score: 27.9 bits;  conditional E-value: 7.6e-11
                 HHHHHHHHHHH-TT-CHHHHHHHHHHC CS
        PPTA   1 ELeltekliekdpkNYsaWnyRrwlle 27 
                 EL++ +k+  k+ kNY++W++R+ ll+
  EEA22830.1  97 ELAWLNKVSLKYLKNYQIWHHRQQLLS 123
                 9************************97 PP

  == domain 3  score: 34.3 bits;  conditional E-value: 7e-13
                 HHHHHHHHH-TT-CHHHHHHHHHHCH CS
        PPTA   3 eltekliekdpkNYsaWnyRrwllek 28 
                 ++ +++ + d kNY++W+yR+wl+++
  EEA22830.1 137 DFLMQMFDSDSKNYHVWSYRQWLVRQ 162
                 6899*******************986 PP

  == domain 4  score: 22.4 bits;  conditional E-value: 3.8e-09
                 HHHHHHH-TT-CHHHHHHHH CS
        PPTA   5 tekliekdpkNYsaWnyRrw 24 
                 ++ lie+d +N+saWn+R+ 
  EEA22830.1 175 VDALIEMDVRNNSAWNHRYL 194
                 6789**************86 PP

  == domain 5  score: 19.2 bits;  conditional E-value: 3.9e-08
                 HHHHHHHHHHH-TT-CHHHHHHHHHHC CS
        PPTA   1 ELeltekliekdpkNYsaWnyRrwlle 27 
                 EL++ +k+i + p N s W y r++l+
  EEA22830.1 232 ELDYAQKKILLAPENRSPWLYARGVLR 258
                 9************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (350 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       410  (0.022868); expected 358.6 (0.02)
Passed bias filter:                      290  (0.0161749); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.45u 0.28s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 2472.74
//
Query:       EEA22831.1  [L=452]
Description: L-serine dehydratase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-50  172.1   0.1    5.9e-50  170.3   0.1    1.7  2  PALP      Pyridoxal-phosphate dependent enzyme


Domain annotation for each model (and alignments):
>> PALP  Pyridoxal-phosphate dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  170.3   0.1   3.3e-54   5.9e-50       6     274 ..      36     343 ..      32     360 .. 0.92
   2 ?   -1.1   0.0     0.054   9.6e+02     147     178 ..     412     443 ..     397     449 .. 0.72

  Alignments for each domain:
  == domain 1  score: 170.3 bits;  conditional E-value: 3.3e-54
                 SS--EEEECCTCCCCCCEEEEEEGGGSTTSBTTHHHHHHHHHHHHTT....TTTSEEEEEBSSHHHHHHHHHHHHHT-EEEEEEETTS-HHHHHHHHHT CS
        PALP   6 gpTPlvrlprlskelgvplflKlEslnptgSfKdRgaeyllarlkeg....tgaktvveassGNhgralAaaaallGlkvtivvpadaspekvallrll 100
                  +TPl+++  lsk+ g+++flKlE+ +p+gSfK R++++l++++ ++    +++ + +  s+GN+g+a+ +aa+ l +++t+vvp ++s  +v++l + 
  EEA22831.1  36 IETPLIESAILSKKAGCRIFLKLENIQPGGSFKSRAMASLILHHINHpsntNKRLHFFINSGGNAGLAAVCAARSLSYPCTVVVPTSTSRLMVDKLCAA 134
                 68*****************************************999999999*********************************************** PP

                 T-.EEEEECCHHHHHHHHHHHHHHH............STTCEE--TTTSHHHHHHHHTHHHHHHHHTT.............TTEEEEEEE-SSSHHHHH CS
        PALP 101 Ga.evvevggdydeavaaaaelaae............gegaylvsqfdnptviegygtiglEileqlg.............gkpdavvvpvGgGgliaG 173
                 Ga +v++ g++  +a +++ +++ +            g + + +++fd+++++eg +ti+ E+++ql+                dav+++vGgGgl+ G
  EEA22831.1 135 GAtQVIQHGDTIAAAGEYMTNILMNdhssgneggegeGVKKIALHPFDHEAIWEGNSTIVDELAAQLPpadddnddgeedtLPMDAVICSVGGGGLMNG 233
                 *9788888888999999977777777999******999999***********************9999999999999998888999************* PP

                 HHHHHHH.....HSTT-EEEEEEECTTCGGTTCCS..S.SS..B.SSS.CCSTCSCGTTCCHHHH....SEEEEEEEEEEHHHHHHHHHHHHHHHSB-B CS
        PALP 174 iaaglke.....rrpdvrvigvepegsdalarslragrrvtvpvsdtiadglavgspselafell....drlvdeivtvsdeealeamrllarregivv 263
                 + +g++      ++ d+++++ve++g  +++ ++     vt+p+ +++a +la+ ++s ++f+++     +       +sd++a++++ +la +e+i+v
  EEA22831.1 234 LIQGIQRhrssqKKKDIHILAVETDGTQSMNLAMSSRTLVTLPKITSMAVSLACVRVSQRTFDYCvsppPGVKIHSAVLSDADAARGCLRLADDERILV 332
                 *******655544444*************************************************8887555557999********************* PP

                 -HHHHHHHHHH CS
        PALP 264 epssaaalaal 274
                 e ++++ + a+
  EEA22831.1 333 ELACGVCVEAA 343
                 ******99999 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.054
                 HHHHHHHTTTTEEEEEEE-SSSHHHHHHHHHH CS
        PALP 147 glEileqlggkpdavvvpvGgGgliaGiaagl 178
                   E++ +l  +  +v+  +Gg    +G+a   
  EEA22831.1 412 LREMIPDLTSQSRVVIIVCGGSNVTTGMAGEW 443
                 56777777777777777788877777777555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (452 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       398  (0.0221987); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 2982.16
//
Query:       EEA22832.1  [L=583]
Description: methionyl-tRNA synthetase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.3e-97  325.3   2.8    6.8e-96  321.4   2.8    2.1  1  tRNA-synt_1g  tRNA synthetases class I (M)
    8.9e-25   87.0   1.2    4.1e-11   41.8   0.1    3.1  3  tRNA-synt_1   tRNA synthetases class I (I, L, M and V)
    1.4e-11   44.3   0.1    2.1e-05   24.1   0.0    2.3  2  tRNA-synt_1e  tRNA synthetases class I (C) catalytic domain
    2.3e-05   24.4   0.0    5.9e-05   23.1   0.0    1.7  1  Anticodon_1   Anticodon-binding domain of tRNA
  ------ inclusion threshold ------
       0.15   12.2   0.0         34    4.7   0.0    2.6  2  HTH_AraC      Bacterial regulatory helix-turn-helix proteins,


Domain annotation for each model (and alignments):
>> tRNA-synt_1g  tRNA synthetases class I (M)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  321.4   2.8   1.9e-99   6.8e-96       2     390 ..      58     424 ..      57     425 .. 0.91

  Alignments for each domain:
  == domain 1  score: 321.4 bits;  conditional E-value: 1.9e-99
                   EEEE--B--SS---HHHHHHHHHHHHHHHHHHHTT-E.EEEEEEE---SHHHHHHHHHTTS-HHHHHHHHHHHHHHHHHHTT---SEEEETTSHHHH CS
  tRNA-synt_1g   2 lvttalpYangklHlGhllevisaDifaRykrlrgee.vlfvcgtDehGtpielkAekegvtpeelvekvheeikelfkklnisfdkygrttseehk 97 
                   +vtt+++Y+n+++H+Ghl++++ +D++ R+++l+g+   +f++gtDehG++i+++A+++g++ + +++ + +++k+l +  +is+d+++rtt+e+hk
    EEA22832.1  58 YVTTPIFYVNAAPHVGHLYSMVLGDVIKRWQQLKGNTnAIFLTGTDEHGIKIQQAAQEAGMDTQSFCDMNCKTFKDLARAAKISNDHFIRTTDEAHK 154
                   8*********************************88659********************************************************** PP

                   HHHHHHHHHHHHTT-EEEEEEEEEEETTTTEEE-GGG-EE........-TTS-EE.-TTSSB-E................EEE.EEEEEE-GGGGHH CS
  tRNA-synt_1g  98 elvqeifkklkekgliyekeieqlycpkderflpdryvegtCPkckseeargdqc.eecgkkleptelinpksaisgskpevketehlffklskfek 193
                   ++v+ +++ l+++g+iy+k+ e++y+++de f+p+++ve   P    ++ r   +  e                 +g++ e++++ ++ f+ls+f++
    EEA22832.1 155 DAVRYFWESLQHRGYIYTKKHEGWYSVSDEAFYPQSQVE---PSLDPATGRKRMIsTE-----------------TGKEVEWSSEINYHFRLSAFKD 231
                   *************************************97...5444333333333234.................445555777999********** PP

                   HHHHHH.HH-TT..SHHHHHHHH.HHHHT----EE-E...SS-SSS-EETTECCEEE-HHHHHHHHHHHTTTTT-...TTSGGGG.G--S......E CS
  tRNA-synt_1g 194 klkewieeeeke..leenvkkivkewlkegLkdlais...rdldwGipvPgaekkvlYVWldAligYisatkelakkkgeeekwkeyWakdkevelv 285
                   +l e++e ++++  l +n  + +k++++++L+dl+is    +l wG++vPg++++++YVWldAli+Y++  ++ + + g+  + +  W +       
    EEA22832.1 232 RLLEFYE-QNPKfiLAKNHMRHLKKTVEADLQDLSISrpvERLTWGVRVPGDDSQTIYVWLDALINYLTKAGYPF-TPGK--ESDLGWPA-----DL 319
                   ******5.55555999*********************6666899******************************9.3333..33444733.....48 PP

                   EEEEGGGHHHHHTHHHHHHHHTT----S-EEEE--EEE--------------HHHHHHHH-HHHHHHHHHHHS-TTS-EEE-HHHHHHHHHHHCCCH CS
  tRNA-synt_1g 286 hfigkdiikFHtifwPaillgaelklpkkvvaheyltvegkKlSkSrgvvvkakealerldadllRYylaaeapekkDldfswedfvervNseLadk 382
                   h++gkdi++FH+i+wPa+l++ +l lp++v +h+++t++ +K+SkS g+vv +  a++r+++d++R++l+  +p  +D++++ +++v+ + + L   
    EEA22832.1 320 HIVGKDIVRFHCIYWPAFLMALDLPLPRHVLVHGHWTMNKAKMSKSTGNVVNPFFAIDRFSVDVMRFFLTLRGPLIDDSNYENNNIVNDYKKYLQYG 416
                   ************************************************************************************************* PP

                   HHHHHHHH CS
  tRNA-synt_1g 383 lgnlvnRv 390
                   +gn+ +R 
    EEA22832.1 417 VGNVYQRL 424
                   ****9997 PP

>> tRNA-synt_1  tRNA synthetases class I (I, L, M and V)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.8   0.1   1.2e-14   4.1e-11      17     115 ..      49     146 ..      42     159 .. 0.86
   2 !    2.7   0.0    0.0081        29     367     432 ..     209     280 ..     203     281 .. 0.76
   3 !   39.7   0.0   5.3e-14   1.9e-10     485     597 ..     285     396 ..     281     401 .. 0.88

  Alignments for each domain:
  == domain 1  score: 41.8 bits;  conditional E-value: 1.2e-14
  tRNA-synt_1  17 ekekekkefilvdgPPyvtGslHiGhalaktlkdivirykrmkGk.evlyvpGwDhaGlaieakvekklgakekkerkklgreefrekvrewkaeyae 113
                  e+e  kk+f ++ +  yv+ ++H+Gh +  +l d++ r++++kG+ ++ +++G+D +G+ i+++ ++  g +  ++  ++  + f++  r+ k    +
   EEA22832.1  49 EAESPKKPFYVTTPIFYVNAAPHVGHLYSMVLGDVIKRWQQLKGNtNAIFLTGTDEHGIKIQQAAQEA-GMDT-QSFCDMNCKTFKDLARAAKISNDH 144
                  567779**************************************735789************998776.5555.58999***9999999988776665 PP

  tRNA-synt_1 114 ei 115
                   i
   EEA22832.1 145 FI 146
                  55 PP

  == domain 2  score: 2.7 bits;  conditional E-value: 0.0081
  tRNA-synt_1 367 rskkpiiyrateqWfvrvkeladaalkave.kvqfvpks.kekryaswl.eniqdWciSR...qrwWGhrip 432
                   ++k ++  +   ++ r+++++d +l+  e + +f+  + + ++ ++ + ++ qd  iSR    ++WG+r+p
   EEA22832.1 209 ETGKEVEWSSEINYHFRLSAFKDRLLEFYEqNPKFILAKnHMRHLKKTVeADLQDLSISRpveRLTWGVRVP 280
                  5677888888888999999999999999887666665552444455555279********666689****98 PP

  == domain 3  score: 39.7 bits;  conditional E-value: 5.3e-14
  tRNA-synt_1 485 dvlDvWFsSgswpfstlgypeedteelkkffpadmlleGlDiirgWvarlillslaltgsePfkevlvhglvrdeeGrKmSKslgNvidpldvikkyg 582
                  +++ vW +      +  gyp++  +e +  +pad+ + G Di+r+       + +al    P ++vlvhg  + ++  KmSKs gNv++p   i++ +
   EEA22832.1 285 QTIYVWLDALINYLTKAGYPFTPGKESDLGWPADLHIVGKDIVRFHCIYWPAFLMALDLPLP-RHVLVHGHWTMNK-AKMSKSTGNVVNPFFAIDRFS 380
                  56779999999999*******************************99999999899988888.88*****988776.69******************* PP

  tRNA-synt_1 583 adalRltli.lsdvgr 597
                  +d++R++l    +   
   EEA22832.1 381 VDVMRFFLTlRGPLID 396
                  ********95555555 PP

>> tRNA-synt_1e  tRNA synthetases class I (C) catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.0   5.8e-09   2.1e-05      19     145 ..      66     193 ..      48     216 .. 0.78
   2 !   17.9   0.0   4.3e-07    0.0015     204     282 ..     313     390 ..     309     407 .. 0.84

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 5.8e-09
                   TTS--BHHHHHHHHHHHHHHHHHHHTT-.EEEEEEEBB--SHHHHHHHHHTTS-HHHHHHHHHHHHHHHHHHTT----SB--BGGG.GHHHHHHHHH CS
  tRNA-synt_1e  19 vydashlGhaRslvafDilrrilqalgY.dvqfvqnvtDidDkiikrareeeksvkelaekfieefkkdleaLnvlkptleprvse.kvdeiielve 113
                   v  a h+Gh  s+v  D+++r+ q +g  +  f+    +   ki + a+e++  ++++++   + fk+  +a ++ + ++     e + d++  + e
    EEA22832.1  66 VNAAPHVGHLYSMVLGDVIKRWQQLKGNtNAIFLTGTDEHGIKIQQAAQEAGMDTQSFCDMNCKTFKDLARAAKISNDHFIRTTDEaHKDAVRYFWE 162
                   44678********************87615666666666667999999999******************9****9996654444332567788899* PP

                   HHHHTTSEEE-TTS-EEE-GGG-TTTTTTTT- CS
  tRNA-synt_1e 114 kliekgyaYavsdgdvyfdvskkeeYgklskq 145
                    l ++gy Y+ +  +  ++vs++  Y + + +
    EEA22832.1 163 SLQHRGYIYTKK-HEGWYSVSDEAFYPQSQVE 193
                   **********99.7888999999999876655 PP

  == domain 2  score: 17.9 bits;  conditional E-value: 4.3e-07
                   H-SSEEEEEEEGGGTTTHHHHHHHHHHHHSSS--EEEEEEE--EEETTBE--TTTT---BHHHHHTTS-HHHHHHHHHS CS
  tRNA-synt_1e 204 lgseidihsGGiDLafPhhenelaqseaafdkqlvkyflhnghlkiegekmsksLknfitikdvlkkfdprqlRlllls 282
                   lg   d+h  G+D++  h     a  +a  d +l ++ l +gh ++++ kmsks +n++    ++ +f+  ++R++l+ 
    EEA22832.1 313 LGWPADLHIVGKDIVRFHCIYWPAFLMA-LDLPLPRHVLVHGHWTMNKAKMSKSTGNVVNPFFAIDRFSVDVMRFFLTL 390
                   6667788888888887777776666665.68899999999***********************************9974 PP

>> Anticodon_1  Anticodon-binding domain of tRNA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.1   0.0   1.7e-08   5.9e-05       3     108 ..     453     552 ..     451     574 .. 0.81

  Alignments for each domain:
  == domain 1  score: 23.1 bits;  conditional E-value: 1.7e-08
  Anticodon_1   3 wilselnklvkevteayeeyrfnkaasalyeffwndlcdwylelvkprlysesaedkraaqevllevletllrllaPfmPfitEelwqreeeelgkke 100
                  ++ + l++l + v++ +e ++ + a+++l +  ++  +++y+  + p+ ++++ +   ++ +++ e+l+   +ll+PfmP+ + el     +++g ++
   EEA22832.1 453 EFEKYLQELPAIVDRFMEAFNSKAALRELVDGAMK--AQNYFHRSAPWEHKDDLTRCARVLYNVSEFLRISGILLQPFMPQKSSELL----DRIGVSR 544
                  566789999999*******************9665..78*********98866533333669999**********************....8888877 PP

  Anticodon_1 101 simlaewp 108
                  +++ + + 
   EEA22832.1 545 DLSARGFA 552
                  77666565 PP

>> HTH_AraC  Bacterial regulatory helix-turn-helix proteins, AraC family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   0.0    0.0095        34       7      26 ..     105     124 ..     104     125 .. 0.89
   2 ?    4.7   0.0    0.0095        34      10      29 ..     130     149 ..     127     152 .. 0.89

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.0095
                 CT--HHHHHHHTTSSHHHHH CS
    HTH_AraC   7 tnltiediAdelgfSrsyFs 26 
                 ++++i + A+e+g++ + F+
  EEA22832.1 105 HGIKIQQAAQEAGMDTQSFC 124
                 6789**********999998 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.0095
                 -HHHHHHHTTSSHHHHHHHH CS
    HTH_AraC  10 tiediAdelgfSrsyFsrlF 29 
                 t +d+A ++ +S  +F+r+ 
  EEA22832.1 130 TFKDLARAAKISNDHFIRTT 149
                 899**************985 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (583 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       534  (0.0297841); expected 358.6 (0.02)
Passed bias filter:                      465  (0.0259356); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.66u 0.27s 00:00:00.93 Elapsed: 00:00:00.49
# Mc/sec: 3574.15
//
Query:       EEA22833.1  [L=155]
Description: nuclear transport factor 2 domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-08   33.8   0.0    5.8e-08   33.3   0.0    1.3  1  NTF2      Nuclear transport factor 2 (NTF2) domain
    9.7e-06   25.6   0.2    6.5e-05   22.9   0.2    1.9  1  Mtr2      Nuclear pore RNA shuttling protein Mtr2


Domain annotation for each model (and alignments):
>> NTF2  Nuclear transport factor 2 (NTF2) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.3   0.0   6.5e-12   5.8e-08       2     107 ..      17     134 ..      16     153 .. 0.88

  Alignments for each domain:
  == domain 1  score: 33.3 bits;  conditional E-value: 6.5e-12
                 HHHHHHHHHHHHHHHGGGGGGGGEEEEEEEEEETTEEEEESHHHHHHHHHHSSCSCEEEEEEEEEEEE..............TSEGGGCEEEEEEEEEE CS
        NTF2   2 akafvqqYYaaldagdregllalyaadaslltpegsspvkgreaIteffrslpftrielkittvdaqp..............deaslstgvlvmvtGel 86 
                 a+ fvq Y +al + + + ++ +y+   + + ++g+  +   +a+++ f++   t+ +++i++vd+q                e++ + ++lv v+G++
  EEA22833.1  17 ATDFVQLYHSALSS-NKRLIASFYSSAITNILFNGN-VIADGAAVEDIFTNQLPTT-RHDIQSVDCQIinkayptakpgntaRENAKNISMLVTVSGSV 112
                 578***********.5666*****9***********.9999999999999988887.***********************9977888999********* PP

                 EETTSCCE.EEEEEEEEEEEET CS
        NTF2  87 kvddfkkr.rkfsqtfilapqs 107
                 +  ++ ++ + fs tf+l p+ 
  EEA22833.1 113 QYGGKDSPqHGFSETFVLIPNT 134
                 *99887667***********98 PP

>> Mtr2  Nuclear pore RNA shuttling protein Mtr2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.2   7.3e-09   6.5e-05      29     121 ..      35     144 ..      17     155 .] 0.66

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 7.3e-09
                 HHCCB-SSS-EEEETTEEESSHHHHHHHHHHHS--EEEEEEEEEEEEET.............TTS....EEEEEEEEEEEEBTTSB-TT--BSB.---- CS
        Mtr2  29 flqlFlkpqckivfngkPlaqaaaFlkiwlqsvvltqHaltalDfHvip.............gtg....tliinanckvrfdesGrdklGqdst.lpae 109
                  +  ++   ++i+fng+ +a+ aa  +i++++  +t H+++++D+ +i+               +    ++++ +++ v++  +   ++G++ t + ++
  EEA22833.1  35 IASFYSSAITNILFNGNVIADGAAVEDIFTNQLPTTRHDIQSVDCQIINkayptakpgntarE-NakniSMLVTVSGSVQYGGKDSPQHGFSETfVLIP 132
                 3444578889**************************************955544433222110.01112355666666666555555666655423455 PP

                 -----------B CS
        Mtr2 110 aakaldkarplw 121
                 ++++++k+r+ w
  EEA22833.1 133 NTESKEKNRKDW 144
                 666666666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (155 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       450  (0.025099); expected 358.6 (0.02)
Passed bias filter:                      348  (0.0194099); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.30s 00:00:00.77 Elapsed: 00:00:00.49
# Mc/sec: 959.02
//
Query:       EEA22834.1  [L=87]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.3e-06   26.2   0.1    1.3e-05   25.4   0.1    1.4  1  Ish1      Putative stress-responsive nuclear envelope protein
  ------ inclusion threshold ------
      0.015   15.0   0.2       0.24   11.2   0.0    2.1  2  SAP       SAP domain
      0.046   13.6   0.5       0.05   13.4   0.5    1.1  1  MFAP1     Microfibril-associated/Pre-mRNA processing
      0.087   12.8   0.0       0.11   12.5   0.0    1.1  1  COX4      Cytochrome c oxidase subunit IV


Domain annotation for each model (and alignments):
>> Ish1  Putative stress-responsive nuclear envelope protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.4   0.1   2.8e-09   1.3e-05       3      37 .]      48      81 ..      47      81 .. 0.93

  Alignments for each domain:
  == domain 1  score: 25.4 bits;  conditional E-value: 2.8e-09
        Ish1  3 tWSdsdLkkWLdshGipvskaastRdeLlklardn 37
                 W++++Lk WL   ++ + + +++R+ L++ +r n
  EEA22834.1 48 EWTTEELKRWLRARNLMP-SDEASREALIERVRAN 81
                5**************885.9999**********87 PP

>> SAP  SAP domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   5.4e-05      0.24       3      18 ..      48      63 ..      46      63 .. 0.92
   2 ?    1.9   0.1     0.045     2e+02      24      32 ..      71      79 ..      70      82 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 5.4e-05
                T--HHHHHHHHHHTT- CS
         SAP  3 kltVaeLKeeLkkrGL 18
                 +t  eLK  L++r+L
  EEA22834.1 48 EWTTEELKRWLRARNL 63
                69************98 PP

  == domain 2  score: 1.9 bits;  conditional E-value: 0.045
                HHHHHHHHH CS
         SAP 24 KaeLieRLk 32
                ++ LieR++
  EEA22834.1 71 REALIERVR 79
                789****97 PP

>> MFAP1  Microfibril-associated/Pre-mRNA processing
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.5   1.1e-05      0.05      87     126 ..      40      80 ..      24      87 .] 0.84

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 1.1e-05
                 SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHHHHH CS
       MFAP1  87 ldpeaeyeaWklReLkRikrdreereerekekee.lerrrn 126
                  dp+ e e+W + eLkR  r+r+   + e  +e  +er+r+
  EEA22834.1  40 PDPKGEPEEWTTEELKRWLRARNLMPSDEASREAlIERVRA 80 
                 4899*******************998888877653688886 PP

>> COX4  Cytochrome c oxidase subunit IV
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   2.5e-05      0.11      72     117 ..      14      59 ..       3      63 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 2.5e-05
        COX4  72 kvlggvlillglslllfllirlfvagpvpkTlskewqeaqlermld 117
                   lg++ i+ ++s++ ++   +f a+p pk   +ew  ++l+r l 
  EEA22834.1  14 LLLGFAGIITAVSAWSIWGSDMFPAEPDPKGEPEEWTTEELKRWLR 59 
                 5678888999********************************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (87 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       401  (0.022366); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        46  (0.00256568); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.36u 0.25s 00:00:00.61 Elapsed: 00:00:00.40
# Mc/sec: 647.02
//
Query:       EEA22835.1  [L=80]
Description: 60S ribosomal protein L38, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.7e-32  110.7   3.1    3.1e-32  110.5   3.1    1.1  1  Ribosomal_L38e  Ribosomal L38e protein family


Domain annotation for each model (and alignments):
>> Ribosomal_L38e  Ribosomal L38e protein family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.5   3.1   1.7e-36   3.1e-32       1      68 [.       2      70 ..       2      71 .. 0.96

  Alignments for each domain:
  == domain 1  score: 110.5 bits;  conditional E-value: 1.7e-36
  Ribosomal_L38e  1 PkeikdiKeFLeiarrkDaksvkikknk.kdntKfKvRcsryLYTLvvkdkekaeklkqsLppglkvke 68
                    P e++diK+F+ei+rrkDa+s++ik+++ +++tKfKvRc+r+LYTLv+kd++ka+klkqsLpp lk+ +
      EEA22835.1  2 PSEVSDIKQFIEICRRKDASSARIKRSTkTTQTKFKVRCNRFLYTLVLKDSDKADKLKQSLPPALKIVD 70
                    89***********************877699***********************************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (80 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       836  (0.0466284); expected 358.6 (0.02)
Passed bias filter:                      439  (0.0244855); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.23s 00:00:00.63 Elapsed: 00:00:00.41
# Mc/sec: 587.20
//
Query:       EEA22836.1  [L=245]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      3e-20   73.3   0.0    3.8e-20   73.0   0.0    1.1  1  Acetyltransf_3  Acetyltransferase (GNAT) domain
    0.00075   19.4   0.0       0.15   12.0   0.0    3.0  3  FR47            FR47-like protein
  ------ inclusion threshold ------
       0.18   11.5   2.3       0.25   11.1   2.3    1.2  1  Cwf_Cwc_15      Cwf15/Cwc15 cell cycle control protein


Domain annotation for each model (and alignments):
>> Acetyltransf_3  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   73.0   0.0   6.4e-24   3.8e-20       2     138 .]      14     201 ..      13     201 .. 0.88

  Alignments for each domain:
  == domain 1  score: 73.0 bits;  conditional E-value: 6.4e-24
  Acetyltransf_3   2 LlLrplteeDlealfelrsdpevmry.lpepltleeaeewlerawaeeseeegygwaiv..................lkdtgviGsvglrdleee 77 
                     +lL+p++++++ +++e+++d+ ++++  +epltl+e+++++++ w+++   ++++++ +                  + ++++iG+ +l+ ++++
      EEA22836.1  14 VLLVPYSKRHVLKYHEWMKDEGIQQAtASEPLTLSEEYAMQQS-WRQD--ADKLTFIAClplsfppsfakdsiseedDAPERMIGDTNLFLRSDD 105
                     69********************99986777************6.9885..577899999778888887777665432244449*******99999 PP

  Acetyltransf_3  78 dee..............aelgymlaps.fwgkGyateavralleyafeel....................glerlvavidkeNeaSirvleklGf 137
                     d+               +e+++m+a++  +g+G+++ a+  +l y+ +++                    +++ l ++i k+N +S +++e+lGf
      EEA22836.1 106 DDDddddcneaeekrviGEIELMIAEKrNQGQGFGRGALLTFLWYVASHEgeildeflqsttttdskkhgKMKCLSVKIGKDNARSLALFESLGF 200
                     98899********************88799****************8777888999999999999999988999********************* PP

  Acetyltransf_3 138 e 138
                     e
      EEA22836.1 201 E 201
                     7 PP

>> FR47  FR47-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.0     0.024   1.4e+02      19      40 ..     119     141 ..     111     159 .. 0.85
   2 !   12.0   0.0   2.6e-05      0.15      57      80 ..     180     203 ..     165     207 .. 0.88
   3 ?    0.8   0.0     0.081   4.9e+02      50      77 ..     215     242 ..     213     244 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.024
                 -TT.SSEEEEEE-GGG-SSSHHH CS
        FR47  19 kdg.gelgalqvlpehrrrGlgs 40 
                 k + ge+  +  ++  +++G+g+
  EEA22836.1 119 KRViGEIELMIAEKRNQGQGFGR 141
                 44449****************97 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 2.6e-05
                 EEEEEETT-HHHHHHHHHHT-EEE CS
        FR47  57 vllvvvasNtpsirlyeklGfeki 80 
                 +++ ++ +N +s +l+e+lGfek 
  EEA22836.1 180 LSVKIGKDNARSLALFESLGFEKV 203
                 5788999**************996 PP

  == domain 3  score: 0.8 bits;  conditional E-value: 0.081
                 HHHS-S-EEEEEETT-HHHHHHHHHHT- CS
        FR47  50 iaergktvllvvvasNtpsirlyeklGf 77 
                 +++ g +v +vv+ +Nt   + y  lG+
  EEA22836.1 215 LRRYGLDVDAVVKLANTYGLKDYRELGY 242
                 5677889999****************99 PP

>> Cwf_Cwc_15  Cwf15/Cwc15 cell cycle control protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   2.3   4.1e-05      0.25     113     162 ..      80     134 ..      21     138 .. 0.59

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 4.1e-05
                 -------------------..........------------------------------- CS
  Cwf_Cwc_15 113 addedseeeeeeeeeesdd..........dsdsdsdddddedetaeLlrELekikrerae 162
                 +d+ ++e++  e+                d+d+d+ddd +e e++  + E+e + +e+ +
  EEA22836.1  80 KDSISEEDDAPER-----MigdtnlflrsDDDDDDDDDCNEAEEKRVIGEIELMIAEKRN 134
                 4444333322222.....022234677545555556666699999999999988777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (245 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       513  (0.0286129); expected 358.6 (0.02)
Passed bias filter:                      456  (0.0254337); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.45u 0.29s 00:00:00.74 Elapsed: 00:00:00.44
# Mc/sec: 1673.21
//
Query:       EEA22837.1  [L=544]
Description: DNA polymerase delta subunit 2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.7e-46  156.8   0.0    6.2e-46  156.4   0.0    1.2  1  DNA_pol_E_B  DNA polymerase alpha/epsilon subunit B
    5.1e-39  133.4   0.0    7.6e-39  132.8   0.0    1.3  1  DNA_pol_D_N  DNA polymerase delta subunit OB-fold domain


Domain annotation for each model (and alignments):
>> DNA_pol_E_B  DNA polymerase alpha/epsilon subunit B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  156.4   0.0   6.9e-50   6.2e-46       1     210 [.     224     474 ..     224     475 .. 0.95

  Alignments for each domain:
  == domain 1  score: 156.4 bits;  conditional E-value: 6.9e-50
                  EEEEES--S-...TT----HHHHHHHHHHH.......HTT--SEEEEES-SSBTTSHHHHHT---..............S--SSHHHHHHHHTHHHHT CS
  DNA_pol_E_B   1 vvivsglnld...ndnrsleaLrkiLqgya......peesppdvlilaGnfvdaahkaiasskvs..............tdekkenfdalalllsile 75 
                  +++vsgl ++   +d ++le+L ++L gy       ++ + +++li+aGn++    ++ a ++++              +d++++n  ++++l+++l+
   EEA22837.1 224 IAFVSGLGITgssSDTLTLELLTDYLLGYTetgeedNSPANISRLIIAGNSLGNVETMDAAAAMNgdaaakkrapkkygYDASSYNASPVTQLDNFLS 321
                  789****99944455555***************99999999***********988888888888799999**************************** PP

                  TS-TTSEEEEE--TTBTT-S-SBSB----TTTTT--TTT...............EEE--BSEEEEETTEEEEE--S-HHHH---EEESHHHH...... CS
  DNA_pol_E_B  76 sllekttvvlvPgpnDpanstvlPqqPlprlllsrikrvfk............elklvtNPsrielnsvevvltsddivkdlkreslkesnt...... 155
                  +ll++++v+++Pg+ Dpan  +lPqq ++r++l+r k++++            ++++vtNP++  ++++++ ++s+++v+d+ r+    +++      
   EEA22837.1 322 ELLPSIPVTIMPGETDPANF-SLPQQGIHRAMLPRAKTYCSdglpgdtsvepgWFDNVTNPWEGYVDGWRLWGCSGQNVDDVLRYLDFADENgntdgd 418
                  ********************.*****************************************************************99999999*999 PP

                  .HS-HHHHHHHHHHHHTBS---SS.--B-GGGGGGGB-GGG---SEEE---SS--EE CS
  DNA_pol_E_B 156 .dverlrklvktildqrhlaPlap.tlrpvswdkddalvleplPdvlvlpdelpeFa 210
                    +e   ++++++l++r+ +P+ap tl++++++  d+++l+ +P+++++++ +p+F 
   EEA22837.1 419 sARETSVQVMEAMLRWRCAVPTAPdTLWCYPFQTHDPFILQACPHLFFIGN-QPHFK 474
                  88888899*******************************************.****7 PP

>> DNA_pol_D_N  DNA polymerase delta subunit OB-fold domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.8   0.0   8.5e-43   7.6e-39       1     130 []      48     187 ..      48     187 .. 0.96

  Alignments for each domain:
  == domain 1  score: 132.8 bits;  conditional E-value: 8.5e-43
  DNA_pol_D_N   1 QYaniYfaRleqlkprlleaakekw......skeelkvnrildlkegeecivvGtiykemklkpsvlkeiakedesapqaerkkyvse....kdellL 88 
                  QY+++Yf+Rl++lkp + +  +e+w       +++ kv+r+ld+++g  c+v Gt+y++++lkp++l+++ak++++a +++rk+y+++    + +++L
   EEA22837.1  48 QYSDLYFLRLAKLKPAAEKVGREAWdgftiaGEKARKVDRVLDVRQGALCWVTGTVYMNLPLKPNILDDVAKDNYAAAPPPRKTYLDPsnpdQTQVML 145
                  *************************999998677889**************************************************87777889*** PP

  DNA_pol_D_N  89 EDesgrvrLsgsgieseklvtGvvvavlGvetengdfeVedi 130
                  EDesgr+r++gs+++ ++lvtGv++avlG+e++ngdfeV di
   EEA22837.1 146 EDESGRLRMTGSMLRTTHLVTGVIIAVLGTENSNGDFEVIDI 187
                  ***************************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (544 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       267  (0.0148921); expected 358.6 (0.02)
Passed bias filter:                      253  (0.0141112); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 3699.60
//
Query:       EEA22838.1  [L=346]
Description: oxidoreductase, 2-nitropropane dioxygenase family, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.4e-57  195.5   0.3    2.1e-57  195.0   0.3    1.2  1  NMO             Nitronate monooxygenase
    1.9e-07   30.4   0.2    9.3e-06   24.9   0.2    2.3  1  IMPDH           IMP dehydrogenase / GMP reductase domain
     0.0016   17.5   3.6     0.0034   16.5   2.9    1.8  2  FMN_dh          FMN-dependent dehydrogenase
  ------ inclusion threshold ------
      0.014   15.7   0.5      0.028   14.8   0.5    1.4  1  ATP-synt_I      ATP synthase I chain
      0.026   14.7   0.0       0.33   11.1   0.0    2.2  2  NAD_binding_2   NAD binding domain of 6-phosphogluconate dehy
      0.036   13.4   0.1       0.05   12.9   0.1    1.1  1  Radial_spoke_3  Radial spoke protein 3
       0.19   10.8   1.5       0.33   10.0   1.5    1.3  1  Glu_synthase    Conserved region in glutamate synthase


Domain annotation for each model (and alignments):
>> NMO  Nitronate monooxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  195.0   0.3   8.4e-61   2.1e-57       2     330 ..       5     327 ..       4     328 .. 0.88

  Alignments for each domain:
  == domain 1  score: 195.0 bits;  conditional E-value: 8.4e-61
         NMO   2 slltellkikppvvqpgmggiskarLaaavsnaGgLGvlasgyltaDrlakeirkvkaltdk...Pfgvnlflpkkdaadraekykkeleeaalelnie 97 
                 ++l +ll+ik+p+  +gm   s+++LaaavsnaGgLG++++   t+ +l + + ++k+l      Pfgv l lp+   + r           a +    
  EEA22838.1   5 TPLCDLLGIKHPILLAGMAKASGPELAAAVSNAGGLGSIGGLGYTPEQLDEMLIELKSLLRDpnlPFGVDLALPQVGGGAR-----------ATNHDYT 92 
                 6899************************************87789977777777777776544459*********999988...........4555566 PP

         NMO  98 egvrfyrkvevvldekvevvsfgfglpteevvarlkeagvvliptissvkearkvearGaDalivqGpeaGGhqGtpevgdkglfaLvpqvldavd... 193
                  g   ++ +e++ ++++++ + ++g+p+e+ v+rl+eag++++ ++++ k+a k+ +rG D++ +qG+e+GGh+G+++        L+p v+dav+   
  EEA22838.1  93 HGHL-DELIELIIKHGTKLFICAVGVPPEHTVKRLHEAGILIMNMVGAPKHAEKALQRGVDIICAQGGEGGGHTGDVPF-----SVLIPAVVDAVQkyk 185
                 6666.6778999999999*********************************************************6666.....69************* PP

         NMO 194 ......iP.viAaGGiidrrgvaaaLalGAsgvqigtrfLltkesdakdahkkklleaklddteltsavsGrpaRalatelleelee..akiatlalpe 283
                        P v+AaGG++d+r +aa L lGAsgv +gtr+L+t es+a+++hk++++ a++ +t  t  vsGrp R+l ++ +++ e+  + i+ l  + 
  EEA22838.1 186 spltgkTPlVVAAGGVNDGRSLAASLMLGASGVWVGTRLLATVESGASKLHKEAVISAGFGETIRTLVVSGRPLRVLPNDYIKQWESrpQDIQKLTEKG 284
                 ******88578***************************************************************************8555555565555 PP

         NMO 284 ahelakkiraalveagnteegllwagqgidrldkiisvkeLiesLve 330
                  + +   i + + +     +  +  g++  +++ki ++ e++e++ +
  EEA22838.1 285 IIPMMHDIEQEVEDV----DFPFLMGSVSAMVKKIQPAGEVVEDMAK 327
                 567777777777666....5566778888899999999999999875 PP

>> IMPDH  IMP dehydrogenase / GMP reductase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.9   0.2   3.6e-09   9.3e-06      22     250 ..       2     235 ..       1     248 [. 0.71

  Alignments for each domain:
  == domain 1  score: 24.9 bits;  conditional E-value: 3.6e-09
                 B--EESSTTEEESSSEEE-SSTTT-SHHHHHHHHHTTSEEEE-SS.S-HHHHHHHHHHHHTSTTSXBXTTSXB-EEEEE........-SSTTH.HHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxx.xxxxx RF
       IMPDH  22 dlktkltkkiklniPlvsaamdtvtesemAialareGgigvihkn.lsieeqaeevkkvkrspnaakdekgrllvgaav........gvkeda.lervk 110
                 +l+t l++ + ++ P++ a m   ++ e+A a++++Gg+g i     ++e+  e++ ++k+     +d +  + v  a+         +++d+ + +++
  EEA22838.1   2 SLQTPLCDLLGIKHPILLAGMAKASGPELAAAVSNAGGLGSIGGLgYTPEQLDEMLIELKSL---LRDPNLPFGVDLALpqvgggarATNHDYtHGHLD 97 
                 789999999*********************************98735666666777788844...3333333333333321111000222222022222 PP

                 HHHHTT-SEEEEE-STSSSHHHHHHH....HHHHHHTTTSEEEEEEE-SHHHHHHHHHTT-SEEEE-SS-STTBHHHHHCSB---HH.HHHHHHHHHHC CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxx RF
       IMPDH 111 alveagvdvlvvdsahghsekvleav....keikkkveeveviaGnvataegakaLieagadavkvGiGpGsiCttrvvagvGvpql.tAvaevaeaak 204
                 +l    ++   + + hg +  ++ +     +++k+ +e   +i   v   + a++ ++ g+d++    G G   t  v  +v +p +  Av +  +  +
  EEA22838.1  98 EL----IE---LIIKHGTKLFICAVGvppeHTVKRLHEAGILIMNMVGAPKHAEKALQRGVDIICAQGGEGGGHTGDVPFSVLIPAVvDAVQKYKSPLT 189
                 22....22...2334444433332211111344444444347888889999***************99****************985269999999999 PP

                 TCT-EEEEES---SHHHHHHHHHTT-SEEEESCCCTTBTTSSSEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       IMPDH 205 kagvpviaDGGikysgdivkAlaaGadavmlGsllagteEspgevi 250
                  +   v+a GG++  + ++ +l +Ga+ v +G  l +t Es ++++
  EEA22838.1 190 GKTPLVVAAGGVNDGRSLAASLMLGASGVWVGTRLLATVESGASKL 235
                 99999***************************99999999987765 PP

>> FMN_dh  FMN-dependent dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   2.9   1.3e-06    0.0034     224     307 ..     137     228 ..     122     247 .. 0.74
   2 ?   -1.7   0.0      0.44   1.1e+03      56      84 ..     298     329 ..     296     340 .. 0.77

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 1.3e-06
                 E-SHHHHHHHHHTTESEEEE--..GGGTSSTT---HHHCH.HHHHHHH..........SS-EEEESS--SHHHHHHHHHTT-SEEEESHHHHHHH CS
      FMN_dh 224 vltaedakraveaGvdgivvSN..HGGRqldgapatidvL.peiveavgg........rievlvDgGirrGsDvlkAlalGAdavllGRpflygl 307
                 v  ++ a++a++ Gvd+i       GG+  d    +++vL p++v+av++           v++ gG+  G   +  l lGA++v++G  +l  +
  EEA22838.1 137 VGAPKHAEKALQRGVDIICAQGgeGGGHTGD---VPFSVLiPAVVDAVQKykspltgkTPLVVAAGGVNDGRSLAASLMLGASGVWVGTRLLATV 228
                 667899**********998754113444444...3444444999999964444455524567889***********************8887654 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.44
                 EESSSEEE--B.STGGGTSTTHHHH..HHHHH CS
      FMN_dh  56 klslPvliaPv.glaklahpdgela..laraa 84 
                 ++++P+l+++v ++ k ++p ge+   +a++a
  EEA22838.1 298 DVDFPFLMGSVsAMVKKIQPAGEVVedMAKEA 329
                 57899999999899999999999973344443 PP

>> ATP-synt_I  ATP synthase I chain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.8   0.5   1.1e-05     0.028      12      76 ..     194     254 ..     192     256 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 1.1e-05
  ATP-synt_I  12 vlalgwlltgsasvalsallGglisvlpfalfalrvfrfsgalarkkkkivrslylgeairlalt 76 
                 +++++ ++ ++ s a s+ lG+  +++ + l+a+     sga++  k  +v s+ +ge ir +++
  EEA22838.1 194 LVVAAGGVNDGRSLAASLMLGASGVWVGTRLLATVE---SGASKLHK-EAVISAGFGETIRTLVV 254
                 5677788999**************************...99999944.55556********8875 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0      0.17   4.4e+02      45      75 ..     119     149 ..      72     162 .. 0.71
   2 ?   11.1   0.0   0.00013      0.33      26      89 ..     268     342 ..     261     345 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.17
                    E-SSHHHHHHHCSEEEE-SSSHHHHHHHHHS CS
  NAD_binding_2  45 aaesieelvasldvvitmvkagkavdevieg 75 
                    + ++++ l ++  +++ mv a k+ ++ +++
     EEA22838.1 119 PEHTVKRLHEAGILIMNMVGAPKHAEKALQR 149
                    4445555555557899999999999988776 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00013
                    EEE-SSHHHHHHHHHTT.EEE-SSHHHHHHHC......SEEEE-SSSHHHHHHHHHS....HCCC--TT-EEEE- CS
  NAD_binding_2  26 avynrtkekveelvaeg.akaaesieelvasl......dvvitmvkagkavdevieg....llealkkgdilidg 89 
                      ++ +++ +++l ++g + ++++ie+ v+++        v  mvk+ ++  ev+e+     +e l+kg+++i +
     EEA22838.1 268 KQWESRPQDIQKLTEKGiIPMMHDIEQEVEDVdfpflmGSVSAMVKKIQPAGEVVEDmakeAVEVLQKGQTFIKS 342
                    568889999********6677899********8888888889999888887777777666689999******986 PP

>> Radial_spoke_3  Radial spoke protein 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.1     2e-05      0.05     226     281 ..     274     331 ..     260     335 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 2e-05
  Radial_spoke_3 226 psvlesLedsgy..fydpverdveteflpwLmeeveeelekrkearelldelirevve 281
                     p+ +++L+++g+  ++ ++e++ve+  +p Lm +v++ ++k + a e+++++ +e+ve
      EEA22838.1 274 PQDIQKLTEKGIipMMHDIEQEVEDVDFPFLMGSVSAMVKKIQPAGEVVEDMAKEAVE 331
                     667899999998334789*************************************998 PP

>> Glu_synthase  Conserved region in glutamate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   1.5   0.00013      0.33     211     309 ..     134     227 ..     121     235 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00013
                   E-STTHHHHHHHHHHTT-SEEEEE-TT--..-SSEEHHHHHHB---HHHHHHHHHHHHHHTT-GGG-EEEEESS--SHHHHHHHHHHT-SEEE-SHH CS
  Glu_synthase 211 vaeagvetiaagvakanadiilidGleGG..TGAspkssikhaGlPlelalaevdqtlkeeglrdrvsliadGglktgadvvkalalGAdavgigta 305
                       g+ ++a  + + ++dii  +G eGG  TG +p s+       l+ a++ ++q+ k+    +   + a+Gg+  g+ ++ +l+lGA  v +gt 
    EEA22838.1 134 MNMVGAPKHAEKALQRGVDIICAQGGEGGghTGDVPFSV-------LIPAVVDAVQKYKSPLTGKTPLVVAAGGVNDGRSLAASLMLGASGVWVGTR 223
                   555667777777889999999999999985556555554.......3446777777777777788888999*************************8 PP

                   HHHH CS
  Glu_synthase 306 alia 309
                    l +
    EEA22838.1 224 LLAT 227
                   8765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (346 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       426  (0.0237604); expected 358.6 (0.02)
Passed bias filter:                      375  (0.0209158); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.59u 0.28s 00:00:00.87 Elapsed: 00:00:00.48
# Mc/sec: 2168.85
//
Query:       EEA22839.1  [L=446]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      6e-93  311.4  58.1      6e-93  311.4  58.1    1.8  2  Taxilin       Myosin-like coiled-coil protein
      0.007   16.2  17.2      0.007   16.2  17.2    3.8  4  ERM           Ezrin/radixin/moesin family
  ------ inclusion threshold ------
        0.3   11.6   4.3        6.4    7.4   0.2    2.9  2  DUF3675       Protein of unknown function (DUF3675)
        2.6    5.5  47.8        3.9    4.8  46.7    1.8  1  DUF3584       Protein of unknown function (DUF3584)
        5.6    5.5  43.7        1.2    7.8  34.8    2.2  2  GOLGA2L5      Putative golgin subfamily A member 2-like prote
        8.2    6.7  37.6       0.69   10.2   7.7    3.3  3  zf-C4H2       Zinc finger-containing protein


Domain annotation for each model (and alignments):
>> Taxilin  Myosin-like coiled-coil protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.3     0.077   2.3e+02      11      52 ..      13      54 ..       4      56 .. 0.64
   2 !  311.4  58.1     2e-96     6e-93       1     308 []      52     350 ..      52     350 .. 0.99

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.077
     Taxilin 11 sklespeekleaLvkkyaelleerkrlqkqlkklkkkleqlq 52
                +k+++p+e  + L  k+++l ++    + q+ + ++++++ +
  EEA22839.1 13 KKMADPNETSKLLAAKISQLEQDAAGEKDQEAEIEREVKKAT 54
                566666777777777777777666666666666666665554 PP

  == domain 2  score: 311.4 bits;  conditional E-value: 2e-96
     Taxilin   1 keaeqlkeslsklespeekleaLvkkyaelleerkrlqkqlkklkkkleqlqkekeqlqaelskaalaksKLekLcRelqkqnkklkeeskqrareeee 99 
                 k++++l+++ls++esp+ +le+++kky+ell+e+k+l+++++k+kk+++qlqk++++ ++el+k+a++k+KLekLcRel+k+nkk+k+e+k++ ++e++
  EEA22839.1  52 KATRDLNQLLSNIESPMTRLETVHKKYTELLAEMKKLDRDYTKSKKRADQLQKDQDKGKSELNKTATMKDKLEKLCRELTKENKKVKDENKKLEETEKR 150
                 799************************************************************************************************ PP

     Taxilin 100 krkelaekfqakLkdiqaqieekserneklreenae..lteKlkslieqyelreehfekllktkelelqlaeaKlqqadallkeeqekkkrekeyllke 196
                 +r  ++e++ + L+diq++++ k++r+    +  ++  +++K+k++ e++elre hf+ ll++k+ e+q   aK+         e++k+++e e+  ++
  EEA22839.1 151 ARMIVNERLSSLLTDIQDVMAPKETRKYAKMDIDMDdaIRTKIKTIGEKFELREFHFKALLRSKDAEIQSLVAKY---------EEQKRAAETEA--SR 238
                 ************************99999888888889*************************************.........***********..** PP

     Taxilin 197 akeltkkvkalketekelkeqlnlYaeKfeefqdtLakSnelFatFkkEmekmtkktkklEketnlwkskfektnkallemaeertekkkeieklkkki 295
                 +++lt++v+++++te el++qln+Y+eKf++++dtL++SnelF tF+kEme+m+kktk+lEke++++++k+++tn+++lemaeer+++++e+ek +kk+
  EEA22839.1 239 CRALTAQVSTFSHTEVELRSQLNIYVEKFKQVEDTLNNSNELFLTFRKEMEEMSKKTKRLEKENLTLTRKHDQTNRNILEMAEERNRNQQELEKYQKKC 337
                 *************************************************************************************************** PP

     Taxilin 296 qkLeklcraLqee 308
                 ++Le lcr +qe+
  EEA22839.1 338 HHLEALCRRMQEQ 350
                 ***********98 PP

>> ERM  Ezrin/radixin/moesin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4  29.4      0.16   4.8e+02      26     160 ..      13     148 ..       3     183 .. 0.58
   2 ?    0.2   4.3      0.18   5.5e+02      77     110 ..     208     241 ..     174     260 .. 0.70
   3 !   16.2  17.2   2.4e-06     0.007       9      97 ..     262     350 ..     254     354 .. 0.94
   4 ?   -3.6   0.3       2.7   8.1e+03      48      73 ..     397     422 ..     384     423 .. 0.66

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.16
         ERM  26 eaLreseetaelLaekarraeeeaelLeqkaaeaeeeiqrlkesaekeeeekeklerklreaeleaarleeeserkeeeaerLkeeleeareaeeeake 124
                 +++ + +et++lLa k  ++e++a   + ++ae+e+e ++  ++ ++  ++ e+ +++l+ +  + ++l  e+++ +++ ++ k+++ + ++++ + k+
  EEA22839.1  13 KKMADPNETSKLLAAKISQLEQDAAGEKDQEAEIEREVKKATRDLNQLLSNIESPMTRLETVHKKYTELLAEMKKLDRDYTKSKKRADQLQKDQDKGKS 111
                 566677788888888888888888777777777777777777777777677666667777777777777777777777777777777777777777777 PP

         ERM 125 kllealstpskses.eenveeseteeeeenseeesae 160
                 +l + ++++ k e+ + + ++++++ ++en++ e++e
  EEA22839.1 112 ELNKTATMKDKLEKlCRELTKENKKVKDENKKLEETE 148
                 7777777664442222222222222222222222211 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.18
         ERM  77 keklerklreaeleaarleeeserkeeeaerLke 110
                 k+ l  k +e ++++a+ ee++++ e ea+r ++
  EEA22839.1 208 KALLRSKDAEIQSLVAKYEEQKRAAETEASRCRA 241
                 5666677777777777777777776666665443 PP

  == domain 3  score: 16.2 bits;  conditional E-value: 2.4e-06
         ERM   9 eleerLkqlqeeaekaqeaLreseetaelLaekarraeeeaelLeqkaaeaeeeiqrlkesaekeeeekeklerklreaeleaarleee 97 
                  + e+ kq+++  ++ +e      +++e++ +k +r+e+e   L++k+ + ++ i +++e+++++++e ek ++k ++ e++ +r++e+
  EEA22839.1 262 IYVEKFKQVEDTLNNSNELFLTFRKEMEEMSKKTKRLEKENLTLTRKHDQTNRNILEMAEERNRNQQELEKYQKKCHHLEALCRRMQEQ 350
                 5779999********************************************************************************97 PP

  == domain 4  score: -3.6 bits;  conditional E-value: 2.7
         ERM  48 eaelLeqkaaeaeeeiqrlkesaeke 73 
                 +++    +++e e+  qr+ e+a +e
  EEA22839.1 397 DEDGVMSDEEEYEAIRQRFPEQATME 422
                 44445556677777777777777765 PP

>> DUF3675  Protein of unknown function (DUF3675)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   0.2    0.0022       6.4       5      69 ..     171     242 ..     168     248 .. 0.78
   2 ?    4.7   0.5     0.014        43      22      67 ..     302     345 ..     275     348 .. 0.77

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0022
     DUF3675   5 appklfqlgrtainirgsweis....geredledprllalaaaerelles...eydeysaanarsaaccRsv 69 
                 ap++  +++++ i++ ++++++    ge+ +l++ ++ al+ ++++ ++s   +y+e ++a+++ a+ cR +
  EEA22839.1 171 APKETRKYAKMDIDMDDAIRTKiktiGEKFELREFHFKALLRSKDAEIQSlvaKYEEQKRAAETEASRCRAL 242
                 6777777888777777766666667789999999999999887777666655599999***********986 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.014
     DUF3675  22 sweisgeredledprllalaaaerelleseydeysaanarsaaccR 67 
                 +++ + +++d+ ++++l++a +er+  ++e ++y+++ ++  a cR
  EEA22839.1 302 NLTLT-RKHDQTNRNILEMA-EERNRNQQELEKYQKKCHHLEALCR 345
                 44444.67899999999998.5667788899999998888777777 PP

>> DUF3584  Protein of unknown function (DUF3584)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.8  46.7    0.0013       3.9     234     531 ..      55     342 ..      14     351 .. 0.68

  Alignments for each domain:
  == domain 1  score: 4.8 bits;  conditional E-value: 0.0013
     DUF3584 234 iqalaaiekvrpeieklqeefeqleslelrLsllkgelkadeerlaekqeevqeakaelkqqlrtledelkeaidelnqelsaakaklaakeseleale 332
                 +++ + + +++  +++l+   ++   l+++++ l +++ + ++r  + q+++++ k el++     ++ +k++ ++l  el ++++k++  +++le+ e
  EEA22839.1  55 RDLNQLLSNIESPMTRLETVHKKYTELLAEMKKLDRDYTKSKKRADQLQKDQDKGKSELNK-----TATMKDKLEKLCRELTKENKKVKDENKKLEETE 148
                 3333344555555555555555555555666666666666666666666666655555554.....455666778888999999*************** PP

     DUF3584 333 eqkkkyedadieklkadld..qlpsirseleeleeel.daltekhqdvqekydrrkqkikeeleeeleklkerleaireekdrlkaaieealealesql 428
                 ++++   ++++++l  d    ++p+  +++++++ ++ da+ +k++ + ek++ r++  k  l  + +++++ +++  e+k +  +++ +   al +q 
  EEA22839.1 149 KRARMIVNERLSSLLTDIQdvMAPKETRKYAKMDIDMdDAIRTKIKTIGEKFELREFHFKALLRSKDAEIQSLVAKYEEQKRA-AETEASRCRALTAQV 246
                 **************9998734579999999999988735899****************************9998877777666.555566666666665 PP

     DUF3584 429 rkqleaqkeelneeekelesrlselklrldsatateEeleqi.eeadealekaqeelekaeaevealqaeeeqlrkkrdeadealqkaerrleqlrqal 526
                           +++ e el+s+l+    + +++  t + + ++   + +++e++ ++ ++ e+e+  l++++ q + +  e  e +++ ++ le  ++++
  EEA22839.1 247 S--------TFSHTEVELRSQLNIYVEKFKQVEDTLNNSNELfLTFRKEMEEMSKKTKRLEKENLTLTRKHDQTNRNILEMAEERNRNQQELEKYQKKC 337
                 5........555666666666555555555555555444443135667777777777777777777777777777777777777777777777777777 PP

     DUF3584 527 eelee 531
                 + le 
  EEA22839.1 338 HHLEA 342
                 77764 PP

>> GOLGA2L5  Putative golgin subfamily A member 2-like protein 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8  34.8   0.00039       1.2     201     438 ..      23     306 ..      19     313 .. 0.66
   2 ?    2.1   2.4      0.02        59     281     328 ..     314     360 ..     304     422 .. 0.68

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.00039
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.......XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
    GOLGA2L5 201 kelakklGqlqeelgelketlelksqeaqslqeqrdqylahlqqY.......vaayqqlasekeelhkqlllqtqlmdrlqheevqgkvalelarkeLq 292
                 k la k+ ql  + +  k++  + ++e+++  ++ +q+l+ ++            y +l +e  +l +++ +  +  d+lq+++ +gk +l+++ +  +
  EEA22839.1  23 KLLAAKISQLEQDAAGEKDQEAEIEREVKKATRDLNQLLSNIESPmtrletvHKKYTELLAEMKKLDRDYTKSKKRADQLQKDQDKGKSELNKTATMKD 121
                 568888888877776666666666666666666666665555544444444499*************************************99887666 PP

                 XXXXXXXXXXXXXXXXXXXXXXXXXXXX..........................XXXXXXXXX.......XXXXXXXXX.XXXXXXXXXX.XXXXXXXX CS
    GOLGA2L5 293 eaqerLealakenqqLkaqlsllaapse..........................Gdgveseek.......eeeakkpkl.sipedlesre.emvaflns 356
                 + ++   +l+ken+++k + ++l ++++                                  k       +++a ++k+ +i e++e re  ++a+l+s
  EEA22839.1 122 KLEKLCRELTKENKKVKDENKKLEETEKrarmivnerlsslltdiqdvmapketR-------KyakmdidMDDAIRTKIkTIGEKFELREfHFKALLRS 213
                 666666899**************9988899************8886665543321.......0233333345677777735899999887345555555 PP

                 XXXXXX...XXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXX......XXXXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
    GOLGA2L5 357 alaqve...eerdelrrqlkeqklrcralaqqvaaarqeeqeke......asaeessedsv..pvevhqaLqvamekLqsrFtelmqekvdLk 438
                   a+++   ++ +e +r  + +  rcral+ qv++ +++e e +       ++ ++ ed++  + e +   +  me + ++   l +e+  L 
  EEA22839.1 214 KDAEIQslvAKYEEQKRAAETEASRCRALTAQVSTFSHTEVELRsqlniyVEKFKQVEDTLnnSNELFLTFRKEMEEMSKKTKRLEKENLTLT 306
                 444433111344444555555666777777777777555555445566663333333443311566666777777777777776666666654 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.02
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
    GOLGA2L5 281 kvalelarkeLqeaqerLealakenqqLkaqlsllaapseGdgvesee 328
                 +  le+a +e ++ q++Le+ +k+ ++L+a  ++++++++G g+   +
  EEA22839.1 314 RNILEMA-EERNRNQQELEKYQKKCHHLEALCRRMQEQGRGHGFTGGD 360
                 3445555.4556677778888888888888888888888866554433 PP

>> zf-C4H2  Zinc finger-containing protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   8.8      0.18   5.4e+02      12      99 ..      29     116 ..      14     120 .. 0.73
   2 ?    7.3   6.8    0.0018       5.3       4      49 ..     115     160 ..     112     169 .. 0.90
   3 ?   10.2   7.7   0.00023      0.69       4     131 ..     217     377 ..     215     441 .. 0.71

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.18
     zf-C4H2  12 leklknklakevealekeekcleeykkelelLeqEkmaHveeLrlIhaDinalEsvikeaeeekekslekakklyeeykklkeevnel 99 
                 +++l++  a e ++  + e+ +++ ++ l++L +  ++ +  L  +h+   +l   +k+ + + +ks+++a +l ++ +k k+e+n++
  EEA22839.1  29 ISQLEQDAAGEKDQEAEIEREVKKATRDLNQLLSNIESPMTRLETVHKKYTELLAEMKKLDRDYTKSKKRADQLQKDQDKGKSELNKT 116
                 4455555555666666667777777777778888888888888888888888888888888888888888888888888888888775 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0018
     zf-C4H2   4 eirektleleklknklakevealekeekcleeykkelelLeqEkma 49 
                 ++ +  ++lekl  +l+ke + +++e+k lee++k   ++ +E+++
  EEA22839.1 115 KTATMKDKLEKLCRELTKENKKVKDENKKLEETEKRARMIVNERLS 160
                 66677799***********************************986 PP

  == domain 3  score: 10.2 bits;  conditional E-value: 0.00023
     zf-C4H2   4 eirektleleklknklakevealekeekcleeykkelelLeqEkmaHveeLrlIhaDinalEsvikeaeeekekslekakklyeeykklkeevnelrse 102
                 ei++ + ++e+ k    +e + +++ +  +++++++  +L +  +  ve+ +++++ +n+  + +   ++e e++ +k+k+l +e   l ++ +++ ++
  EEA22839.1 217 EIQSLVAKYEEQKRAAETEASRCRALTAQVSTFSHTEVELRSQLNIYVEKFKQVEDTLNNSNELFLTFRKEMEEMSKKTKRLEKENLTLTRKHDQTNRN 315
                 678888999999999999************************************************************************999999887 PP

     zf-C4H2 103 .lglekledleeeeeellkeeifekqklk...................................a 131
                  l + + ++ +++e e  ++++   ++l+                                   +
  EEA22839.1 316 iLEMAEERNRNQQELEKYQKKC---HHLEalcrrmqeqgrghgftggdvnhagdhalsgdlegdE 377
                 6666666665555555555555...2222344555555555555555555555555555555550 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (446 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3261  (0.181884); expected 358.6 (0.02)
Passed bias filter:                      549  (0.0306208); expected 358.6 (0.02)
Passed Vit filter:                       159  (0.00886831); expected 17.9 (0.001)
Passed Fwd filter:                        97  (0.00541023); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.78u 0.39s 00:00:02.17 Elapsed: 00:00:00.63
# Mc/sec: 2132.53
//
Query:       EEA22840.1  [L=1066]
Description: pitrilysin family metalloprotease (Cym1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.8e-70  236.9   0.0    2.8e-70  236.3   0.0    1.3  1  M16C_assoc       Peptidase M16C associated
    1.1e-20   74.4   0.0    3.3e-13   50.0   0.0    2.7  2  Peptidase_M16_C  Peptidase M16 inactive domain
    3.6e-11   43.3   0.1    6.4e-10   39.2   0.0    2.9  3  Peptidase_M16    Insulinase (Peptidase family M16)
  ------ inclusion threshold ------
          1    9.9   2.6          2    9.0   0.1    2.7  3  YbaJ             Biofilm formation regulator YbaJ


Domain annotation for each model (and alignments):
>> M16C_assoc  Peptidase M16C associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  236.3   0.0   6.1e-74   2.8e-70       1     251 []     513     771 ..     513     771 .. 0.97

  Alignments for each domain:
  == domain 1  score: 236.3 bits;  conditional E-value: 6.1e-74
  M16C_assoc   1 lkPdeeleeekekeekerLaakkasls......eeekekiveetkeLkerQekpdsedlscLPtLkleDIprei..teleeekeveidgvkvllhevpT 91 
                 + ++++++++++++ek+r ++k ++l       e++++++ + +++L + Qe ++  d+scLPtL+++DI+r++  ++++e+k   +d+v+v+++e+pT
  EEA22840.1 513 MVGSPTYNTDLDEQEKARKDSKLSALIsehgsaEKAIAELEKSELDLLKVQEDAQLADVSCLPTLHVSDISRQKerKPIRESK---VDNVEVVWREAPT 608
                 8899**********************99999***********************77******************666666666...6************ PP

  M16C_assoc  92 NgivYfrllfdlsdlpeellpylpLftdvltelgtkkkdyeeleqeiklktGGisasvsvssspedldkyeegfvlsgkaLdrnvekmfeLlreillet 190
                 Ng++Yf++l  +++lp+el+ ++pLf d++++lgt  +++e++e++iklktGG+s+s+ ++ssp++l ky+eg+++sg+a+d+n++ m+++++ +++et
  EEA22840.1 609 NGLTYFQALSPFDGLPNELRLVMPLFHDCIMRLGTPGRSMEQWEDLIKLKTGGVSTSSYLVSSPTELGKYKEGLQISGFAIDKNIPTMLDIIHALITET 707
                 *************************************************************************************************** PP

  M16C_assoc 191 kfdd...kerlkelvkesksrlensiassGhsyAmsraasslspaaalseqlsGlsqlkflkeL 251
                 +f++    +++ el++++++++ +++a+ Gh++A+++aa++l+++ +++eq sGl+ql++  +L
  EEA22840.1 708 DFTSneaPRMILELLRSTTNGALDAVAGTGHRFAVNAAAATLNESFWVQEQQSGLAQLQATANL 771
                 **99888899*************************************************98876 PP

>> Peptidase_M16_C  Peptidase M16 inactive domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.0   0.0   7.4e-17   3.3e-13       2     177 ..     257     437 ..     256     443 .. 0.86
   2 !   21.7   0.0   3.8e-08   0.00017      80     180 ..     862     954 ..     810     957 .. 0.83

  Alignments for each domain:
  == domain 1  score: 50.0 bits;  conditional E-value: 7.4e-17
                      H-HHHHHHHHHHHSSGGGEEEEEEESS-HHHHHHHHHHHHTTSTHHSH.....CSGSCTSSSSSGGGSSEEEEEEEESSSSSEEEEEEEEEECT CS
  Peptidase_M16_C   2 ltredlkefykkfYrpenmvlaivGdvdheelvkliekyfgdlkaska.....ppakptgepltpatlkkppvvlkkldeeqahlslafegpsk 90 
                      lt e+l +f kk+Y+p+n +++ +Gd +  + +k+i +++ +++ + a      p + +++p ++  + + + +  ++   q + s  +++ ++
       EEA22840.1 257 LTHEQLVQFSKKNYHPSNSKIVTYGDMPLADHLKQIGEVLEGFDRKGAdtdvkLPLDLSQGPTEVTLPGPIDSFTSED--RQYKTSSSWLMGDT 348
                      899*****************************************9888888876666676777744444444444444..68888888888888 PP

                      CTHTTHHHHHHHHHHHHSSTTSHHHHHHHTTTTSESEEEEEEEEES..SCEEEEEEEEEECT.THHHHHHHHHHHHHHHHHHTS-HHHHH CS
  Peptidase_M16_C  91 endeddlalavlntlLgggmesrLytnlrekeglaysvsafndsyr..dsglfgisatadpe.nveevvevilkelrklkkeglteeele 177
                      ++  + +   +l+ lL++g  s+ y++l  ++ l+ s+      ++     +f+i++ +  e +v +v evi+ + ++++ +g+++e ++
       EEA22840.1 349 TDIVETFSTGILSSLLLDGYGSPMYKALI-ESELGSSFTPNTGLDTaaKKPIFSIGVNGVREeDVGKVHEVIRGVYEEVIATGFNDEKVQ 437
                      888**************************.999999998886666667************999************************997 PP

  == domain 2  score: 21.7 bits;  conditional E-value: 3.8e-08
                      EEEEEEEEECTCTHTTHHHHHHHHHHHHSSTTSHHHHHHHTTTTSESEEEEEEEEESSCEEEEEEEEEECTTHHHHHHHHHHHHHHHHHHTS-H CS
  Peptidase_M16_C  80 hlslafegpskendeddlalavlntlLgggmesrLytnlrekeglaysvsafndsyrdsglfgisatadpenveevvevilkelrklkkeglte 173
                      +  la e+++   d++++ l+vl++lL +     L  ++r ++g ay+++a+n   +  g+f++s + dp+   +++ v++k+    ++  +t+
       EEA22840.1 862 YSGLAMETVPF-IDPNSASLSVLSQLLTHK---YLHPEIR-EKGGAYGAGASNGPLK--GIFTLSSYRDPN-PINTLSVFKKTGTFARDRSWTD 947
                      55688999999.9*****************...*******.999**********888..**********88.8889999999998888889999 PP

                      HHHHHHH CS
  Peptidase_M16_C 174 eelerak 180
                      +ele+ak
       EEA22840.1 948 QELEEAK 954
                      9999998 PP

>> Peptidase_M16  Insulinase (Peptidase family M16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.2   0.0   1.4e-13   6.4e-10      22     108 ..      97     186 ..      93     214 .. 0.90
   2 ?   -2.1   0.0      0.76   3.4e+03      91     113 ..     568     591 ..     529     606 .. 0.74
   3 ?   -0.4   0.0      0.23     1e+03      81     107 ..     690     716 ..     688     734 .. 0.85

  Alignments for each domain:
  == domain 1  score: 39.2 bits;  conditional E-value: 1.4e-13
                    SGGGSCTTTTTHHHHHHHHTTSBBSSSCH.HHHHHHHHHTTCEE.EEEEESSEEEEEEEEEGGG.HHHHHHHHHHHHHSBTTSHHHHHHH CS
  Peptidase_M16  22 GSryepkdlnGlAHllehmafkgTkkyps.nklaeeleklGgsl.nAttsrentvYyvevlskd.lekaldvladvfkaplleesevere 108
                    G    p+d  G+ H+leh  + g++kyp  + + ++l +   ++ nA+ts ++t+Y + +++k+ ++++l v  d + +pll+++++++e
     EEA22840.1  97 GFKTNPPDATGVPHILEHTTLCGSEKYPVrDPFFKMLPRSLSNFmNAFTSSDHTTYPFATTNKQdFQNLLSVYLDATLHPLLKKDDFKQE 186
                    6667899******************************99988888***********998888777********************99984 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.76
                    HHHHHHSBTTSHHHHHHHHH.HHH CS
  Peptidase_M16  91 ladvfkaplleesevererk.vve 113
                    ladv   p+l  s+++r+++ +  
     EEA22840.1 568 LADVSCLPTLHVSDISRQKErKPI 591
                    788888899999999995553333 PP

  == domain 3  score: -0.4 bits;  conditional E-value: 0.23
                    GGGHHHHHHHHHHHHHSBTTSHHHHHH CS
  Peptidase_M16  81 skdlekaldvladvfkaplleesever 107
                    +k+++++ld++   ++++ ++++e  r
     EEA22840.1 690 DKNIPTMLDIIHALITETDFTSNEAPR 716
                    57899****************999877 PP

>> YbaJ  Biofilm formation regulator YbaJ
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.1      0.87   3.9e+03      61      84 ..     151     174 ..     136     185 .. 0.81
   2 ?    9.0   0.1   0.00046         2      32     102 ..     462     528 ..     446     545 .. 0.66
   3 ?   -1.5   0.0      0.76   3.4e+03      26      64 ..     762     797 ..     756     805 .. 0.69

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.87
        YbaJ  61 nfkikykeesdlseqideylddty 84 
                 ++    ++++d+ +++  yld t 
  EEA22840.1 151 TYPFATTNKQDFQNLLSVYLDATL 174
                 5666778999***********996 PP

  == domain 2  score: 9.0 bits;  conditional E-value: 0.00046
        YbaJ  32 sehgwvndptsavnlqlneliehiaafvlnfkikykeesdlseqideyl.ddtyalfssygin..eadlrkwqk 102
                 +   w n     ++l  n++       + +fk +y e+  l +++++yl +d y+ f+  g    ++dl + +k
  EEA22840.1 462 TLTSWFNGSDPIKELAWNDV-------INEFKRRYAEDGYLESLVQKYLlNDNYMKFTMVGSPtyNTDLDEQEK 528
                 55555555555555555555.......468*****************954899*99987664311344544443 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 0.76
        YbaJ  26 lavlgesehgwvndptsavnlqlneliehiaafvlnfki 64 
                 la+l+ ++ + +nd t+  + +ln +ie +  ++++f i
  EEA22840.1 762 LAQLQ-ATANLLNDATTS-SEKLNAIIEKLR-LIQSFAI 797
                 55554.455678888876.5699****9874.4556655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1066 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       637  (0.035529); expected 358.6 (0.02)
Passed bias filter:                      548  (0.030565); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.82u 0.32s 00:00:01.13 Elapsed: 00:00:00.49
# Mc/sec: 6586.81
//
Query:       EEA22841.1  [L=259]
Description: oxidoreductase, short chain dehydrogenase/reductase family superfamily [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.8e-22   79.8   0.0    2.4e-22   79.4   0.0    1.1  1  adh_short     short chain dehydrogenase
    8.8e-17   61.4   0.0    1.1e-16   61.1   0.0    1.2  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
       0.01   15.8   0.0       0.02   14.8   0.0    1.5  1  KR            KR domain


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.4   0.0     4e-26   2.4e-22       2     189 ..       3     193 ..       2     198 .. 0.86

  Alignments for each domain:
  == domain 1  score: 79.4 bits;  conditional E-value: 4e-26
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCSHHH CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfselseee 100
                  +l++Ga++G+G  +a ++a+   + +v++ + +   ++ ++ k   +  + ++vD+++++   +lv++++ + ++ld+++ NAG  gs++f   + ++
  EEA22841.1   3 NILIIGATRGLGASLATHYASLPTTSTVYATTRS--FKTPESPKH-DKIRWLLNVDISEADVGYTLVSQIIPDSQTLDMVIVNAGYFGSESFDGPDWQK 98 
                 59********************999988666533..345555554.3446899*********************************8888887777777 PP

                 HHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGG....TSB-TTBHHHH..HHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHH CS
   adh_short 101 wervievNltgvflltravlpamlkqssGrIvnvsSvag....kvpvagvaaYs..AsKaavagltrslakelaptgirvnavaPGlvdTdmake 189
                   r++ +   g++ +++a+++  l +s+G+ + +sS ag    + +++g+  Y+  AsKaa+++  + l+ +l+++gi v +v+PG+++T+m++ 
  EEA22841.1  99 EVRMYTTSAIGPVFAIQALVKRNLVRSGGKFILISSEAGsitlRHESEGGGNYGhhASKAALNMVGKLLSLDLKDKGIAVGMVHPGFMRTEMTRG 193
                 77889999999*******9999888**************44444556778899777************************************975 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.1   0.0   1.9e-20   1.1e-16       1     192 [.       8     203 ..       8     223 .. 0.82

  Alignments for each domain:
  == domain 1  score: 61.1 bits;  conditional E-value: 1.9e-20
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSE.EEE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHH CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneeakkrveelaeelgae.vlecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreefd 96 
                   Ga +g+G+ +A ++a+   +  +    ++   ++ e  +  + + +l++D+++ +   +lv+++  + ++lD+++ nag+  +  ++f   ++++  
    EEA22841.1   8 GATRGLGASLATHYASLPTTSTVYATTRSF--KTPESPKHDKIRwLLNVDISEADVGYTLVSQIIPDSQTLDMVIVNAGYFGS--ESFDGPDWQKEV 100
                   677777777777777766665554444444..23333333344435*************************************..999999****** PP

                   HHHHHHTHHHHHHHHHHHH..HCTSCCEEEEEEEGGGTSBSTTTT......HHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTTH CS
  adh_short_C2  97 raldvnlyslfllakaalp..lmkeggsivnlssvgaervvpnyn......aygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikgf 185
                   r+  +++ + +  ++a+++  l+++gg+ + +ss ++++++ + +        +a+Kaal+ + + l  +l +kgi v  v+pg+++T++++g+  f
    EEA22841.1 101 RMYTTSAIGPVFAIQALVKrnLVRSGGKFILISSEAGSITLRHESegggnyGHHASKAALNMVGKLLSLDLKDKGIAVGMVHPGFMRTEMTRGVG-F 196
                   ******************99999************99988776655555345579***************************************7.8 PP

                   HHHHHHH CS
  adh_short_C2 186 delleel 192
                   d+ +e  
    EEA22841.1 197 DKYYESG 203
                   8877655 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.8   0.0   3.4e-06      0.02       3     142 ..       4     140 ..       2     156 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 3.4e-06
                 EEEETTTSHHHHHHHHHHHHHH.S-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT- CS
          KR   3 ylitGGlGgLGlelarwlaekg.arhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklleem 100
                  li+G++ gLG +la++ a+    +++  ++Rs  ++++s  + ++++       ++++D+s++d   +l+++i  + +++  vi  Ag +  + ++  
  EEA22841.1   4 ILIIGATRGLGASLATHYASLPtTSTVYATTRSF-KTPESP-KHDKIRW------LLNVDISEADVGYTLVSQIIPDSQTLDMVIVNAGYFGSESFDGP 94 
                 69*****************976478888888883.333333.3444443......6889999999999*******999****************99998 PP

                 -HHHHHHHHTTTTHHHH.HHHHHTTT...S--SEEEEEEEHHHHH- CS
          KR 101 taedleqvlapKvkGaw.nLhelled...esldffvlfSSiagllg 142
                 + ++  +++     G    ++ l+++   +s   f+l+SS ag + 
  EEA22841.1  95 DWQKEVRMYTTSAIGPVfAIQALVKRnlvRSGGKFILISSEAGSIT 140
                 8877666665554444303333333344466778888888887664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (259 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       360  (0.0200792); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 1685.79
//
Query:       EEA22842.1  [L=238]
Description: oxidoreductase, short chain dehydrogenase/reductase family superfamily [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.4e-22   80.2   0.0    1.8e-22   79.8   0.0    1.1  1  adh_short     short chain dehydrogenase
    6.6e-17   61.9   0.0    8.5e-17   61.5   0.0    1.2  1  adh_short_C2  Enoyl-(Acyl carrier protein) reductase
     0.0077   16.2   0.0      0.016   15.1   0.0    1.5  1  KR            KR domain


Domain annotation for each model (and alignments):
>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   79.8   0.0     3e-26   1.8e-22       2     189 ..       3     193 ..       2     198 .. 0.86

  Alignments for each domain:
  == domain 1  score: 79.8 bits;  conditional E-value: 3e-26
                 EEEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHTTSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGCSHHH CS
   adh_short   2 vvlvtGassGIGraiakelakeGakvvvvdrseekleevakelkeegakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfselseee 100
                  +l++Ga++G+G  +a ++a+   + +v++ + +   ++ ++ k   +  + ++vD+++++   +lv++++ + ++ld+++ NAG  gs++f   + ++
  EEA22842.1   3 NILIIGATRGLGASLATHYASLPTTSTVYATTRS--FKTPESPKH-DKIRWLLNVDISEADVGYTLVSQIIPDSQTLDMVIVNAGYFGSESFDGPDWQK 98 
                 59********************999988666533..345555554.3446899*********************************8888887777777 PP

                 HHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGG....TSB-TTBHHHH..HHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHHHH CS
   adh_short 101 wervievNltgvflltravlpamlkqssGrIvnvsSvag....kvpvagvaaYs..AsKaavagltrslakelaptgirvnavaPGlvdTdmake 189
                   r++ +   g++ +++a+++  l +s+G+ + +sS ag    + +++g+  Y+  AsKaa+++  + l+ +l+++gi v +v+PG+++T+m++ 
  EEA22842.1  99 EVRMYTTSAIGPVFAIQALVKRNLVRSGGKFILISSEAGsitlRHESEGGGNYGhhASKAALNMVGKLLSLDLKDKGIAVGMVHPGFMRTEMTRG 193
                 77889999999*******9999888**************44444556778899777************************************975 PP

>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   61.5   0.0   1.4e-20   8.5e-17       1     192 [.       8     203 ..       8     223 .. 0.82

  Alignments for each domain:
  == domain 1  score: 61.5 bits;  conditional E-value: 1.4e-20
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGHHHHHHHHHHHTTSE.EEE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-HHHHH CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneeakkrveelaeelgae.vlecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsreefd 96 
                   Ga +g+G+ +A ++a+   +  +    ++   ++ e  +  + + +l++D+++ +   +lv+++  + ++lD+++ nag+  +  ++f   ++++  
    EEA22842.1   8 GATRGLGASLATHYASLPTTSTVYATTRSF--KTPESPKHDKIRwLLNVDISEADVGYTLVSQIIPDSQTLDMVIVNAGYFGS--ESFDGPDWQKEV 100
                   677777777777777766665554444444..23333343344435*************************************..999999****** PP

                   HHHHHHTHHHHHHHHHHHH..HCTSCCEEEEEEEGGGTSBSTTTT......HHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTGGGGSTTH CS
  adh_short_C2  97 raldvnlyslfllakaalp..lmkeggsivnlssvgaervvpnyn......aygaaKaalealtrylAvelgpkgiRvNavspgpikTlaasgikgf 185
                   r+  +++ + +  ++a+++  l+++gg+ + +ss ++++++ + +        +a+Kaal+ + + l  +l +kgi v  v+pg+++T++++g+  f
    EEA22842.1 101 RMYTTSAIGPVFAIQALVKrnLVRSGGKFILISSEAGSITLRHESegggnyGHHASKAALNMVGKLLSLDLKDKGIAVGMVHPGFMRTEMTRGVG-F 196
                   ******************99999************99988776655555345579***************************************7.8 PP

                   HHHHHHH CS
  adh_short_C2 186 delleel 192
                   d+ +e  
    EEA22842.1 197 DKYYESG 203
                   8877665 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   2.7e-06     0.016       3     142 ..       4     140 ..       2     156 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 2.7e-06
                 EEEETTTSHHHHHHHHHHHHHH.S-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT- CS
          KR   3 ylitGGlGgLGlelarwlaekg.arhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklleem 100
                  li+G++ gLG +la++ a+    +++  ++Rs  ++++s  + ++++       ++++D+s++d   +l+++i  + +++  vi  Ag +  + ++  
  EEA22842.1   4 ILIIGATRGLGASLATHYASLPtTSTVYATTRSF-KTPESP-KHDKIRW------LLNVDISEADVGYTLVSQIIPDSQTLDMVIVNAGYFGSESFDGP 94 
                 69*****************976478888888883.333333.3444443......6889999999999*******999*****************9998 PP

                 -HHHHHHHHTTTTHHHH.HHHHHTTT...S--SEEEEEEEHHHHH- CS
          KR 101 taedleqvlapKvkGaw.nLhelled...esldffvlfSSiagllg 142
                 + ++  +++     G    ++ l+++   +s   f+l+SS ag + 
  EEA22842.1  95 DWQKEVRMYTTSAIGPVfAIQALVKRnlvRSGGKFILISSEAGSIT 140
                 8877666665554444303333333344466778888888888665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (238 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       314  (0.0175135); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 1617.24
//
Query:       EEA22843.1  [L=431]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
          2    8.6   5.1       0.45   10.7   1.2    1.9  2  MRPL52    Mitoribosomal protein mL52


Domain annotation for each model (and alignments):
>> MRPL52  Mitoribosomal protein mL52
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.1      0.78   1.4e+04      46      56 ..     223     233 ..     218     242 .. 0.45
   2 ?   10.7   1.2   2.5e-05      0.45      31      86 ..     286     345 ..     283     349 .. 0.87

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 0.78
      MRPL52  46 kqeelakkivk 56 
                 k+++  ++  +
  EEA22843.1 223 KRQKRNRSTTQ 233
                 33333333333 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 2.5e-05
      MRPL52  31 GRpapvtsgqlkrkkkqeelakkivkl....lsEideaeerykkkqeeeeeeeqkiiesk 86 
                 GRp  + sgq  r  k +el+++ +++    +sEi ++ e  k++qe+eeeee +i +++
  EEA22843.1 286 GRPRRTPSGQSSRSGKARELKESRIEIdavrTSEITSMAELSKEEQEAEEEEELEIVRRR 345
                 899999999999999999999988887555579********************9998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (431 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       942  (0.0525406); expected 358.6 (0.02)
Passed bias filter:                      393  (0.0219198); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.45
# Mc/sec: 2890.06
//
Query:       EEA22844.1  [L=361]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.1e-53  178.6   0.0    1.2e-52  178.1   0.0    1.1  1  Methyltransf_16  Lysine methyltransferase
    9.9e-05   22.2   0.0    0.00017   21.4   0.0    1.4  1  Methyltransf_23  Methyltransferase domain
    0.00063   20.4   0.0     0.0015   19.2   0.0    1.7  1  Methyltransf_25  Methyltransferase domain
  ------ inclusion threshold ------
       0.11   12.1   0.0       0.24   11.0   0.0    1.6  1  MTS              Methyltransferase small domain


Domain annotation for each model (and alignments):
>> Methyltransf_16  Lysine methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  178.1   0.0   2.7e-56   1.2e-52       3     173 ..     145     327 ..     143     328 .. 0.96

  Alignments for each domain:
  == domain 1  score: 178.1 bits;  conditional E-value: 2.7e-56
  Methyltransf_16   3 dekeLkieedtgesigrkvWdaavvlvkylekklake...........lganelsklsvlELGsGtGlvGlavaellpeakviltDleellell 85 
                      ++++L+i+e+tg++i+r++Wdaa+++++ l  + +++           ++a++ ++l+v+ELGsG+G+vG+a+ ++l +++v+ltDl e+ +++
       EEA22844.1 145 NNTRLRIWEETGNNIARHIWDAALAAIMCLRDTNNSSgkcsmprlqsrFQAKSKNHLQVIELGSGCGIVGIALSQMLFGCSVTLTDLAEVDDIM 238
                      6889***************************98877799*********99******************************************** PP

  Methyltransf_16  86 kknielnknalkskvkvevLdWgeeleedllekeevDlilaaDcvYledslelLvkvLkellkkesk..vlvaykkrreaekkFfkllek 173
                       +n++l ++a  s+++++vLdW+eel  d+ +++++Dl+l++Dc+Y++dsl++Lv+vL++l++++++  vlv++k+r+e+e  Ff+l+++
       EEA22844.1 239 ARNLQLLQSAPGSEIRFKVLDWDEELGVDV-TEKPIDLVLVSDCTYNADSLPALVQVLDRLVRSSPDavVLVSLKRRHESEAVFFDLMRQ 327
                      ******999*****************9999.5779*****************************99999*****************9976 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0   3.8e-08   0.00017      15     121 ..     192     313 ..     161     348 .. 0.82

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 3.8e-08
  Methyltransf_23  15 rllpklraggrvLdiGcGtGillevlre..ngfsvtgvDlspeaveiae...........kakkaqkdqfdeqeaaepqgkfdlIvlrevlehv 95 
                      r+ +k +    v+++G G Gi+   l++  +g+svt+ Dl +++  +a+           ++++ + d   e   ++ ++ +dl+  ++++++ 
       EEA22844.1 192 RFQAKSKNHLQVIELGSGCGIVGIALSQmlFGCSVTLTDLAEVDDIMARnlqllqsapgsEIRFKVLDWDEELGVDVTEKPIDLVLVSDCTYNA 285
                      44455666669**********999995533799*******9999999988888888888888888888887778888999************** PP

  Methyltransf_23  96 pdppellrqiatllk..pgGylllsepl 121
                      +++p+l++ + +l++  p++++l+s   
       EEA22844.1 286 DSLPALVQVLDRLVRssPDAVVLVSLKR 313
                      ************9997788888887653 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   0.0   3.4e-07    0.0015       1      90 [.     203     299 ..     203     302 .. 0.70

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 3.4e-07
                      EEEET-TTSHHHHHHHCTS.TSSEEEEEESSHH...HHHHHHHHHHHTTTTEEEEESBC.CG..BSSSTTTEEEEEEEST.GGGSSHHHHHHHH CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrl.gkakvtgvDisee...mleaareraeeeglnvefvqgda.ed..lpfedgsfDlvvssga.lhhlsdedlekal 86 
                      v++lG G G + +al++ l g ++vt +D++e    m ++ +   ++ g +++f + d  e+  ++  ++ +Dlv++s + ++  s + l ++l
       EEA22844.1 203 VIELGSGCGIVGIALSQMLfG-CSVTLTDLAEVddiMARNLQLLQSAPGSEIRFKVLDWdEElgVDVTEKPIDLVLVSDCtYNADSLPALVQVL 295
                      789***************978.********87511144444444444555*********55534468999*******98845444444555555 PP

                      HHHH CS
  Methyltransf_25  87 keia 90 
                      +++ 
       EEA22844.1 296 DRLV 299
                      5444 PP

>> MTS  Methyltransferase small domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   5.3e-05      0.24      31      63 ..     199     231 ..     187     277 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 5.3e-05
                 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEES CS
         MTS  31 lsgkvlDlGcGaGvlgaalakespeaevtlvdv 63 
                  + +v+ lG+G G++g+al ++    +vtl+d 
  EEA22844.1 199 NHLQVIELGSGCGIVGIALSQMLFGCSVTLTDL 231
                 4456*********************99*99996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (361 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       371  (0.0206927); expected 358.6 (0.02)
Passed bias filter:                      354  (0.0197445); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.47
# Mc/sec: 2320.48
//
Query:       EEA22845.1  [L=472]
Description: ornithine decarboxylase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-80  270.4   0.0    1.7e-80  270.0   0.0    1.1  1  Orn_Arg_deC_N    Pyridoxal-dependent decarboxylase, pyridoxal
    2.4e-18   66.2   0.0      4e-18   65.4   0.0    1.6  1  Orn_DAP_Arg_deC  Pyridoxal-dependent decarboxylase, C-termina
  ------ inclusion threshold ------
       0.11   11.9   0.0       0.19   11.1   0.0    1.3  1  AP_endonuc_2     Xylose isomerase-like TIM barrel


Domain annotation for each model (and alignments):
>> Orn_Arg_deC_N  Pyridoxal-dependent decarboxylase, pyridoxal binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  270.0   0.0   2.8e-84   1.7e-80       2     247 .]      86     314 ..      85     314 .. 0.98

  Alignments for each domain:
  == domain 1  score: 270.0 bits;  conditional E-value: 2.8e-84
                    HHHHHHHHHHHHHCTCCEEEEEGGG---HHHHHHHHHTTEEEEESSHHHHHHHHHCTTTGGGEEEEESS--HHHHHHHHHCTHTEEEESSHHHHHH CS
  Orn_Arg_deC_N   2 asierklkrwkkalprikvfYavKansdlavlellaelGlgldcaSkaElelvlaagvsperiifanpckqreelryalekgvkvvtvdnveelek 97 
                    +++ r++ rwk +l+rik+fYavK+n+d++vl+l+a+lGlg+dcaSk+E++l+l++g++ +rii+a+pck+r++lrya +kgvk++t+dn +el+k
     EEA22845.1  86 GEVYRQHMRWKMNLGRIKPFYAVKCNPDPEVLRLMAKLGLGFDCASKTEIDLALKTGIDSSRIIYAQPCKTRSYLRYARQKGVKQMTFDNTDELYK 181
                    6899******************************************************************************************** PP

                    HHHHHCCEEEEEEEE-SCCSSSSTCCCSSSTTSSSSEEHCHHHHHHHHHHHHTTEEEEEEE---BSSC-SCHHHHHHHHHHHHHHHHHHHHT---S CS
  Orn_Arg_deC_N  98 laklapeakvllRiktdvsaatcelistggessKFGaaleeavealleaakeenlqlvGvsfHvGSgvsdleafvkavekalklfdelaelGvklk 193
                    +++  p+a++ lRi td+s++ c+l      s+KFGa+l ++++ ll++ak+++l++vGvsfHvGSg++d  af+ka+++a+ +fd++ae+G++l+
     EEA22845.1 182 IKNDFPDAELYLRILTDDSTSLCRL------SMKFGASL-DTARPLLDLAKKLELNVVGVSFHVGSGAEDPGAFLKAAQDARWVFDQAAEVGYELH 270
                    *************************......********.999***************************************************** PP

                    EEE--S-BS-HCSTTSSSSTHHHHHHHHHHHHHHHHHTSSS-EEEE--SHHHHG CS
  Orn_Arg_deC_N 194 iLdvGGGfgveyeeeeeplkleeiaekirealeeafpgdkevtiiaEpGRalva 247
                    +LdvGGGf+ + +       +e+ a  +++a++++fp   +v+iiaEpGR++va
     EEA22845.1 271 TLDVGGGFC-DNT-------FEKFAAILSKAVDDLFP--AHVRIIAEPGRYYVA 314
                    ********4.555.......99**************9..899**********98 PP

>> Orn_DAP_Arg_deC  Pyridoxal-dependent decarboxylase, C-terminal sheet domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.4   0.0   6.8e-22     4e-18       5      98 .]      84     438 ..      14     438 .. 0.71

  Alignments for each domain:
  == domain 1  score: 65.4 bits;  conditional E-value: 6.8e-22
                      E............................................................................................. CS
                      x............................................................................................. RF
  Orn_DAP_Arg_deC   5 d............................................................................................. 5  
                      d                                                                                             
       EEA22845.1  84 Dmgevyrqhmrwkmnlgrikpfyavkcnpdpevlrlmaklglgfdcaskteidlalktgidssriiyaqpcktrsylryarqkgvkqmtfdntd 177
                      4555555555555555555555555555555555555555555556666666666666666666666666666666666666666666666666 PP

                      .............................................................................................. CS
                      .............................................................................................. RF
  Orn_DAP_Arg_deC   6 .............................................................................................. 5  
                                                                                                                    
       EEA22845.1 178 elykikndfpdaelylriltddstslcrlsmkfgasldtarplldlakklelnvvgvsfhvgsgaedpgaflkaaqdarwvfdqaaevgyelht 271
                      6666666666666666666666666666666666666666666666666666666666666666666777777777777777777777777777 PP

                      ...........................................GGEEEEEEEEEEEEETC......EEEEEES--TTTS-HHHHCTT-...... CS
                      ...........................................xxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxx...... RF
  Orn_DAP_Arg_deC   6 ...........................................eagvLvtrViavkesek......kkfvivdaGmndllrpalygsf...... 44 
                                                                  a++L+++Via++++ +      ++++++++G+        yg+f      
       EEA22845.1 272 ldvgggfcdntfekfaailskavddlfpahvriiaepgryyvaAAFTLAANVIARRDVFDpqnssgSYMIYLNDGV--------YGNFsniifd 357
                      77777777777777777777777777777777777777777779************95434556679*********........9999777777 PP

                      ........S-EESBT.......................T-SCEEC.EEEEEEEE-SSSSTT-EEEEEEEEEE.--TT-EEEESS-S CS
                      ........xxxxxxx.......................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxx RF
  Orn_DAP_Arg_deC  45 ........heipvke.......................eeaekeeeeeeevdvvGptCesgDvlakdrelpe.levGdllafedaG 98 
                                    +                       + +++ + +  e++++GptC+++Dv+ ++  lp  ++vGd+l+fed+G
       EEA22845.1 358 hqhpvaqiL-----TcangsipptpgltasgsstpdpsAGDSPCAPAGVEYSIWGPTCDGIDVISQQIVLPGlVDVGDWLYFEDMG 438
                      665555550.....15555555555666666667777644456677889************************************9 PP

>> AP_endonuc_2  Xylose isomerase-like TIM barrel
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   3.2e-05      0.19      26     132 ..     213     309 ..     189     315 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 3.2e-05
                   HHHHHHHHHHHHHHTTSEEEEEEECCCHSTCTHCHTTCSHHHHHHHHHHHHHHHHHHTBSEEEEEBCCGBCTTTSGHHHHHHHHHHHHHHHHHHHHH CS
  AP_endonuc_2  26 sdeelrelrkaldelglriaslslftrfgypdederearreesvdalkraielaaaLGapllvlhpGtagagpkgseeeawerlaeslneladyaek 122
                   s +++r l  ++++l l+++++s++ ++g+ d         ++ ++++   + aa++G +l +l +G      +g  + ++e++a+ l +++d + +
    EEA22845.1 213 SLDTARPLLDLAKKLELNVVGVSFHVGSGAEDPGAFL----KAAQDARWVFDQAAEVGYELHTLDVG------GGFCDNTFEKFAAILSKAVDDLFP 299
                   567788899999*****************95553333....6699********************99......889999****************** PP

                   HTSEEEEE-- CS
  AP_endonuc_2 123 egvklalEtl 132
                   + v++++E++
    EEA22845.1 300 AHVRIIAEPG 309
                   *******996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (472 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       333  (0.0185733); expected 358.6 (0.02)
Passed bias filter:                      322  (0.0179597); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 3329.97
//
Query:       EEA22846.1  [L=375]
Description: CobW domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.6e-42  144.4   0.0    3.9e-42  143.8   0.0    1.2  1  cobW      CobW/HypB/UreG, nucleotide-binding domain
     0.0043   17.3   0.2      0.047   14.0   0.0    2.2  2  AAA_22    AAA domain
     0.0058   16.5   0.0      0.028   14.3   0.0    2.1  2  MobB      Molybdopterin guanine dinucleotide synthesis protei
  ------ inclusion threshold ------
       0.01   15.7   0.0       0.51   10.3   0.0    2.6  2  CobW_C    Cobalamin synthesis protein cobW C-terminal domain
      0.026   14.3   0.1       0.39   10.5   0.0    2.4  2  AAA_29    P-loop containing region of AAA domain
       0.03   13.8   0.1       0.16   11.4   0.0    2.1  2  Pox_A32   Poxvirus A32 protein
      0.099   13.0   0.0       0.21   12.0   0.0    1.6  1  AAA_16    AAA ATPase domain


Domain annotation for each model (and alignments):
>> cobW  CobW/HypB/UreG, nucleotide-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  143.8   0.0   1.5e-45   3.9e-42       1     170 [.       9     184 ..       9     189 .. 0.91

  Alignments for each domain:
  == domain 1  score: 143.8 bits;  conditional E-value: 1.5e-45
                 EEEEEEESTTCCHHHHHHHHH.CT--SS-EEEEESS-SSCHCCCCCCHCCCT..EEEETTTTECCHCTT-HHHHHHHHHHHHTT-SEEEEEECTTTTHH CS
        cobW   1 pvtvltGflGsGKTtLlnhll.enraglklavivNefgevsiDaellretgve.ivelenGciCctlredllkelealeereerldviliEttGlaePa 97 
                 p+t+ltGflGsGKTtLl +ll +    +kla++ Nefg+v+iD++l +e++ + + el nGciCc+l  +l  +l++l ++  ++d+i+iEt+G a Pa
  EEA22846.1   9 PITILTGFLGSGKTTLLLNLLpQLPPTYKLALLKNEFGDVAIDSQLASEQSISgVRELLNGCICCNLVGQLGDALTQLRTEI-KPDRIVIETSGSAFPA 106
                 789*********************************************996666************************9999.9*************** PP

                 HHHTT.......SHHHHHCCCECEEEEEEETTTH.CCHCCHHHHHHHHHHTSSEEEEE-HHHHCHC..HHHHHHHHHHHH CS
        cobW  98 pvaft.......eeelksdltldavvavvDaknleaeeekieekaedqlaaadllvlnKtDlldeeallekleerlrqln 170
                 ++a++       ++++k ++ ld+v+ v+D++n+ +  e+++ +a+ q  ++dl+v+nK++l+de++  + + +rl +l+
  EEA22846.1 107 TLAMEvnrlateNPSTKGQFVLDGVISVIDVENW-QGYEDTSYTAKMQARYTDLIVFNKWELVDERRF-DICLDRLGDLE 184
                 **5545677778999999****************.8*****************************943.67776666665 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.0   0.0   1.8e-05     0.047       7      37 ..      10      40 ..       9      91 .. 0.81
   2 ?    1.0   0.1      0.19   4.7e+02      31      70 ..     231     272 ..     217     304 .. 0.72

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1.8e-05
      AAA_22  7 ilvvtGesGtGKTtllrrlleqldeeakaee 37
                i+++tG  G+GKTtll +ll ql+  +k + 
  EEA22846.1 10 ITILTGFLGSGKTTLLLNLLPQLPPTYKLAL 40
                789******************9987666655 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.19
      AAA_22  31 eeakaee...erpevvfvtlpsstsskdl.lrellralglelka 70 
                 ee k  +    ++ev++ tl+ss + + l l+++ + l+++ k+
  EEA22846.1 231 EEHK--HdhqSEVEVLSLTLSSSQENQVLdLTKFINLLKSSPKE 272
                 2222..24468888999999999944444488888888877766 PP

>> MobB  Molybdopterin guanine dinucleotide synthesis protein B
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   1.1e-05     0.028       4      44 ..      13      52 ..      10      55 .. 0.87
   2 ?   -1.7   0.0      0.99   2.5e+03      86     104 ..     351     369 ..     339     374 .. 0.76

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 1.1e-05
        MobB  4 ivgksgsGKTtLleklipelkarglrvgtiKhahhgfdvdk 44
                ++g+ gsGKTtLl +l+p+l    ++++++K +  ++ +d+
  EEA22846.1 13 LTGFLGSGKTTLLLNLLPQLPP-TYKLALLKNEFGDVAIDS 52
                68999***************75.69******9999998886 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.99
        MobB  86 arlsevDlvlvEGfkkeal 104
                 ++l++ D v vEG k++++
  EEA22846.1 351 KKLETGDYVNVEGSKDSEI 369
                 56777899*****998875 PP

>> CobW_C  Cobalamin synthesis protein cobW C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0    0.0002      0.51       7      41 ..     252     286 ..     224     290 .. 0.91
   2 ?    2.5   0.0     0.055   1.4e+02      42      91 ..     310     354 ..     305     356 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.0002
      CobW_C   7 rarrpfdperleelleeelpegilRaKGivwlagk 41 
                 + ++ +d +++ +ll+++ +e+ +R+KG ++++++
  EEA22846.1 252 QENQVLDLTKFINLLKSSPKEEAYRIKGTIRCSSS 286
                 5678899**********88899*********9876 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.055
      CobW_C  42 pdalvlqgvggrlrlepagawwaaededrrseLVfIGrdldkealeeaLd 91 
                  + + l+ + gr++++p++++ ++       +L fI    + ++ +++L+
  EEA22846.1 310 TTTYILNWAFGRWTFTPTSTPTKD-----VARLTFILARYESAKWKKKLE 354
                 458999999*******99999888.....999999999999888888886 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00015      0.39      24      39 ..      10      25 ..       1      34 [. 0.86
   2 ?    1.0   0.0      0.14   3.5e+02       4      22 ..     135     153 ..     132     161 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00015
      AAA_29 24 atlltGpsGsGKSTll 39
                +t+ltG  GsGK+Tll
  EEA22846.1 10 ITILTGFLGSGKTTLL 25
                699************8 PP

  == domain 2  score: 1.0 bits;  conditional E-value: 0.14
      AAA_29   4 lqlvNWgtfdghtieidlk 22 
                 +++ NW+ +++++++ +++
  EEA22846.1 135 IDVENWQGYEDTSYTAKMQ 153
                 7899*****9987776654 PP

>> Pox_A32  Poxvirus A32 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   6.1e-05      0.16      17      46 ..      12      41 ..       9      53 .. 0.87
   2 ?   -1.6   0.0       0.6   1.5e+03     162     205 ..     241     284 ..     235     289 .. 0.60

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 6.1e-05
     Pox_A32 17 alvGgsGsGktvyLlsLlrtlvkkykhifL 46
                +l+G  GsGkt+ Ll+Ll +l   yk  +L
  EEA22846.1 12 ILTGFLGSGKTTLLLNLLPQLPPTYKLALL 41
                578999*****************9998776 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.6
     Pox_A32 162 ienllrsmslkgskk..kllkvlnilrsaeqkkrkvliiedsvfse 205
                 +e l  + s   +++  +l k++n+l+s+   k + + i+ ++ + 
  EEA22846.1 241 VEVLSLTLSSSQENQvlDLTKFINLLKSSP--KEEAYRIKGTIRCS 284
                 454444444333333227899999999986..66666666666655 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   8.1e-05      0.21      25      63 ..       9      48 ..       2     136 .. 0.61

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 8.1e-05
      AAA_16 25 elvllsGesGvGKsslvrellralekdg.giflrgkcdql 63
                ++++l+G  G+GK++l+  ll +l  ++   +l+ ++ + 
  EEA22846.1  9 PITILTGFLGSGKTTLLLNLLPQLPPTYkLALLKNEFGDV 48
                899**************88888999886455566666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (375 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       621  (0.0346366); expected 358.6 (0.02)
Passed bias filter:                      468  (0.026103); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.44
# Mc/sec: 2568.99
//
Query:       EEA22847.1  [L=165]
Description: hypothetical protein PMAA_094540 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
       0.04   13.3   0.8       0.05   13.0   0.8    1.1  1  Brucella_OMP2  Brucella outer membrane protein 2


Domain annotation for each model (and alignments):
>> Brucella_OMP2  Brucella outer membrane protein 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.8   2.8e-06      0.05      68     105 ..      63     100 ..      58     149 .. 0.72

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 2.8e-06
  Brucella_OMP2  68 vignntsdrtpaasilqaannvrhvavdvvvgrasvvv 105
                     i  nts+ t ++ ilq+a+nv     d+v   +    
     EEA22847.1  63 AISSNTSESTTTSNILQTADNVLNTVGDKVADVTGQHQ 100
                    6899******************9999888854333222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (165 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1388  (0.0774165); expected 358.6 (0.02)
Passed bias filter:                      671  (0.0374254); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.42u 0.31s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 1164.52
//
Query:       EEA22848.1  [L=165]
Description: hypothetical protein PMAA_094540 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
  ------ inclusion threshold ------
       0.04   13.3   0.8       0.05   13.0   0.8    1.1  1  Brucella_OMP2  Brucella outer membrane protein 2


Domain annotation for each model (and alignments):
>> Brucella_OMP2  Brucella outer membrane protein 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.8   2.8e-06      0.05      68     105 ..      63     100 ..      58     149 .. 0.72

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 2.8e-06
  Brucella_OMP2  68 vignntsdrtpaasilqaannvrhvavdvvvgrasvvv 105
                     i  nts+ t ++ ilq+a+nv     d+v   +    
     EEA22848.1  63 AISSNTSESTTTSNILQTADNVLNTVGDKVADVTGQHQ 100
                    6899******************9999888854333222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (165 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1388  (0.0774165); expected 358.6 (0.02)
Passed bias filter:                      671  (0.0374254); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.43
# Mc/sec: 1165.54
//
Query:       EEA22849.1  [L=400]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.029   14.2   0.0        0.1   12.5   0.0    1.8  2  SH3_9     Variant SH3 domain


Domain annotation for each model (and alignments):
>> SH3_9  Variant SH3 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   5.7e-06       0.1      10      36 ..     149     175 ..     148     182 .. 0.85
   2 ?   -2.5   0.0      0.27   4.9e+03       4      11 ..     282     289 ..     281     291 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 5.7e-06
       SH3_9  10 ddeLsLqrGDvitvieesedgWlegsl 36 
                 +de++L++G+ ++v++++ d W ++ +
  EEA22849.1 149 PDEFELRVGELFVVSRMYADMWALCVR 175
                 79********************99853 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 0.27
       SH3_9   4 pyepredd 11 
                 ++epre+d
  EEA22849.1 282 DFEPREED 289
                 89***998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (400 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       510  (0.0284455); expected 358.6 (0.02)
Passed bias filter:                      411  (0.0229238); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.43
# Mc/sec: 2779.19
//
Query:       EEA22850.1  [L=1155]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1155 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       532  (0.0296726); expected 358.6 (0.02)
Passed bias filter:                      323  (0.0180155); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.77u 0.26s 00:00:01.03 Elapsed: 00:00:00.46
# Mc/sec: 7521.65
//
Query:       EEA22851.1  [L=643]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   4.4e-161  537.9  32.7   2.3e-130  436.4  27.7    2.0  2  Mitofilin       Mitochondrial inner membrane protein
     0.0013   17.5   4.7     0.0019   16.9   4.7    1.2  1  Cullin          Cullin family
  ------ inclusion threshold ------
      0.022   14.3   5.3      0.037   13.6   5.3    1.4  1  Cas_DxTHG       CRISPR-associated (Cas) DxTHG family
      0.047   13.7   0.4      0.047   13.7   0.4    2.6  3  Focal_AT        Focal adhesion targeting region
      0.049   12.1   5.0       0.03   12.8   3.1    1.6  1  Lys-AminoMut_A  D-Lysine 5,6-aminomutase TIM-barrel domain of
       0.31   11.1   4.0       0.82    9.8   4.0    1.7  1  Ribosomal_L20   Ribosomal protein L20
        5.2    6.7   6.9       0.85    9.2   1.8    2.2  2  tRNA_anti-like  tRNA_anti-like
        6.4    7.5  16.2         28    5.4   9.4    2.9  2  NAM-associated  No apical meristem-associated C-terminal doma
        6.4    6.8   6.7        7.6    6.5   3.0    2.9  3  HisK_N          Histidine kinase N terminal


Domain annotation for each model (and alignments):
>> Mitofilin  Mitochondrial inner membrane protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.4   0.1   3.7e-33   7.3e-30       2     162 ..     112     260 ..     111     264 .. 0.97
   2 !  436.4  27.7  1.1e-133  2.3e-130     247     623 .]     270     635 ..     261     635 .. 0.98

  Alignments for each domain:
  == domain 1  score: 104.4 bits;  conditional E-value: 3.7e-33
   Mitofilin   2 sgfgkvlvalvlivgvgvGGvvlyakkddeFrdfleksvPyseevvdylleedpplaeklkeisklqvsavsevtkeskepkeekkkeksekqssasse 100
                 ++f+++l++l+l++g+++GG+v++a+k+d+F+df++++vPy+ee v+y++e+d         +++++++a++ +++  + +ke+ ++++++++s+ s++
  EEA22851.1 112 GRFRRFLLYLILTSGIAYGGGVFLALKSDNFHDFFTEYVPYGEESVLYFEERD---------FYRRFPNATRHSNRLPPIHKEQSQRVTIPSKSGLSWK 201
                 79***************************************************.........************************************* PP

   Mitofilin 101 vaeeeaeatkkaaeakaqqpkseqekekaleevlkealskaekataaakeakdeakkavkea 162
                 v+eee ++ + +++     ++s+ +++k + +v++ + +k e+a+++a  +k++a+ a ke+
  EEA22851.1 202 VSEEESDSASLTQKGP---HNSAVDASKDASAVKTVIKAKEESAEKKAPVKKEAAPPAPKEE 260
                 ****************...*********************************9999988876 PP

  == domain 2  score: 436.4 bits;  conditional E-value: 1.1e-133
   Mitofilin 247 klvekykelveeerevFqqelesiipeiitnlkednkklskddlnsliahAkteidqlskelaelkkeeekkieralekqkeelekqeealsarleeer 345
                 + +e +k+  ++e+ v  qel++i+++iit++ +d+    ++++++++    te++ ++++++ l++++ek +++++ek+++ +++++++l++++e++r
  EEA22851.1 270 ATLELIKVEGADEPVV--QELVRIFNDIITVIGADEG--AATKYAAPVSRVRTEVETIGQKISSLRADAEKAAKEEVEKAHALFDESAKKLMQQIEQAR 364
                 56677899999*****..*******************..******************************************88**************** PP

   Mitofilin 346 akeerqlrlelereleeireeyeekLrteLerqaeaheehLkdvlveqeieLkrefqqeikekveeEragrllkLaellaklkglekaleshaeaeden 444
                 a+e++q+r+e+e+e+e++ ++y+ek++teL r++e +e++Lk++lveq+ieL+r+++ ++ke ve+Er+grl+k++el+a++++lek++ ++++++++n
  EEA22851.1 365 AAEAAQFREEFEAEREKLVRAYQEKIQTELSRAQELAEQRLKNELVEQAIELNRKYLNDVKELVERERDGRLSKISELTANVNQLEKLTTDWSDVIESN 463
                 *************************************************************************************************** PP

   Mitofilin 445 rkaqqLwlAveaLrstlksasadkrtrPlkdelkalkelasdDevvkavlaslpeealqrGvyseaaLrerFrkVakevRkvalvdpegagllshalSy 543
                 +k+qqL++Av+a+rs l+ a+     +P+ +el+a+kela+dD+vv+a++as++++a+qrG+++ ++L+erFr+Va evRk++l+ pe+ag++sha+S+
  EEA22851.1 464 LKTQQLQVAVDAVRSVLEGATS---AKPFIRELVAVKELAADDPVVAAAIASINPTAYQRGIPTSSQLIERFRRVAGEVRKASLL-PEDAGIASHAASF 558
                 ********************98...77**********************************************************.************* PP

   Mitofilin 544 llSkllfkpkqgeldvagdDvesiLaRAeyyLeegdLdkAaremnsLkGwskklasDWLkeaRkvlevqqalellqaeaa 623
                 +lSk++fk+++     +gdDves+L R+e++Leeg+Ld Aaremn L+Gw+k l++DWL+++R+vlev+qa+el+++ea+
  EEA22851.1 559 VLSKVMFKRDA---VTDGDDVESVLVRTENLLEEGNLDAAAREMNTLQGWAKILSKDWLADVRRVLEVKQAVELMETEAR 635
                 ********777...47**************************************************************96 PP

>> Cullin  Cullin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   4.7   9.4e-07    0.0019     169     318 ..     348     497 ..     277     513 .. 0.71

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 9.4e-07
      Cullin 169 vYeeeFekafleateefYraeaeella..ensvaseYlkkaeerleeEeervekyldsstkkkllevleeelikkhleelleeelkklledekledLkr 265
                 ++ +e  k++++++e+   aea+++ +  e    ++ ++  +e+++ E +r++++     +++l++ l+e+ i+ + + l +  +k+l+e+e+  +L++
  EEA22851.1 348 LF-DESAKKLMQQIEQARAAEAAQFREefEA-EREKLVRAYQEKIQTELSRAQELA----EQRLKNELVEQAIELNRKYLND--VKELVERERDGRLSK 438
                 44.4557889999999999999999995433.5668999999***********986....5778888888999988866666..69***988******* PP

      Cullin 266 lykllsrvdgleeLrkaleeyikeegkaivkdake......kektedakkyveklLelk 318
                 + +l ++v++le+L +++++ i+++ k+ + + +        e ++ ak ++ +l ++k
  EEA22851.1 439 ISELTANVNQLEKLTTDWSDVIESNLKTQQLQVAVdavrsvLEGATSAKPFIRELVAVK 497
                 ***********************877433332222335555555556666666666555 PP

>> Cas_DxTHG  CRISPR-associated (Cas) DxTHG family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   5.3   1.9e-05     0.037     154     331 ..     259     445 ..     227     495 .. 0.61

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 1.9e-05
   Cas_DxTHG 154 eeeedPildlteflelsdwltaverflktgdaeklaellrekkek.....kkek...lkklkklkeklkkeleefskalelirplellekaekleke.. 242
                 ee ++P + +   lel   ++++++ + ++  + + ++      +        +   +k+++ +++  + e+e + + ++ +r+     +aek+ ke  
  EEA22851.1 259 EEPRTPAIATPATLELI-KVEGADEPVVQELVRIFNDI------ItvigaD--EgaaTKYAAPVSR-VRTEVETIGQKISSLRA-----DAEKAAKEev 342
                 55555555555555555.23333333323333333333......2222231..1333333333333.44488888888888883.....3333333323 PP

   Cas_DxTHG 243 .........iveklkeeleeiesleeeesakplellldeikkklekf.....lkkq..ikwclekgliqqaltllreliisllle..gedilnkkkrre 323
                          + +kl +++e+ + +e++++ + +e + +++ +++++       ++q  ++  l+++l+ qa++l r  +  +  e  +   ++++ r +
  EEA22851.1 343 ekahalfdeSAKKLMQQIEQARAAEAAQFREEFEAEREKLVRAYQEKiqtelSRAQelAEQRLKNELVEQAIELNRKYLNDV-KElvE---RERDGRLS 437
                 33466555566667799999988899999999999888888888888676654444888999**********9999999222.11223...33333333 PP

   Cas_DxTHG 324 eieeelkn 331
                 +i+e ++n
  EEA22851.1 438 KISELTAN 445
                 33333222 PP

>> Focal_AT  Focal adhesion targeting region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.4   2.3e-05     0.047      30     104 ..     302     376 ..     277     387 .. 0.85
   2 ?    0.3   0.4      0.31   6.2e+02      65      90 ..     409     433 ..     378     479 .. 0.55
   3 ?   -3.0   0.0       3.4   6.8e+03      19      40 ..     617     638 ..     614     640 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 2.3e-05
    Focal_AT  30 etakaeeyvslvksvglelrkLltsvdellsslpasarreielaekvlskdlaelisamklaqqyssttldeeyr 104
                 ++  a +y+  v +v +e+ ++ +++ +l    ++ a++e+e a+ + +++ ++l++++++a+ ++  +  ee+ 
  EEA22851.1 302 DEGAATKYAAPVSRVRTEVETIGQKISSLRADAEKAAKEEVEKAHALFDESAKKLMQQIEQARAAEAAQFREEFE 376
                 4556889*********************************************************99999888874 PP

  == domain 2  score: 0.3 bits;  conditional E-value: 0.31
    Focal_AT  65 sarreielaekvlskdlaelisamkl 90 
                  +++ iel +k l+ d++el++  ++
  EEA22851.1 409 LVEQAIELNRKYLN-DVKELVERERD 433
                 23334444444443.44444444444 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 3.4
    Focal_AT  19 vkavvelsqevetakaeeyvsl 40 
                 v+ v+e++q ve +++e  +++
  EEA22851.1 617 VRRVLEVKQAVELMETEARLQC 638
                 7899999999999988887766 PP

>> Lys-AminoMut_A  D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   3.1   1.5e-05      0.03      37     142 ..     270     376 ..     232     404 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.5e-05
                     HHHHHTT--SB-TTS-BHHHHHHHHHHHTT-TTT-HHHHHHHHHHTT---HHHHHHHHHHT---TTTS----HHHHHHHHHHHHHHHHHHHHHHH CS
  Lys-AminoMut_A  37 tvlrllGidgvdeeevPlvnvvvdklkekealekGvalllanalvetekspqeiaekvakgeldltklpaaeeeeikealeelvkkavekikenr 131
                     ++l l+ ++g+de  v    ++ +++      ++G+a+  a  + +  +++++i +k+++ + d +k  ++e e++++  +e +kk +++i+++r
      EEA22851.1 270 ATLELIKVEGADEPVVQELVRIFNDIITVIGADEGAATKYAAPVSRVRTEVETIGQKISSLRADAEKAAKEEVEKAHALFDESAKKLMQQIEQAR 364
                     67789999999999888888888999999999************************************************************998 PP

                     HHHHHH.HHHH- CS
  Lys-AminoMut_A 132 kkreel.lkelg 142
                     ++  +   +e++
      EEA22851.1 365 AAEAAQfREEFE 376
                     765544044444 PP

>> Ribosomal_L20  Ribosomal protein L20
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   4.0   0.00041      0.82       9      96 ..     336     424 ..     329     427 .. 0.71

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.00041
                    XXXXXXXXX--SSS---SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HHTTT--HHHHHHHHCCTTS---HHHHHHH CS
  Ribosomal_L20   9 rkrrkkilklakgyrgrrsklyrvakqavekalqyayrdRkkkkrdfrklwitrinaa.arenglsYskfingLkkanielnRkvLadl 96 
                    ++ ++++ k+ + +  + +kl++ ++qa    ++   ++ ++++++  + ++++i+    r+++l  +++ n+L ++ ielnRk L d+
     EEA22851.1 336 KAAKEEVEKAHALFDESAKKLMQQIEQARAAEAAQFREEFEAEREKLVRAYQEKIQTElSRAQELAEQRLKNELVEQAIELNRKYLNDV 424
                    444555555555566666666666666655555555555667777788888999988625899***********************885 PP

>> tRNA_anti-like  tRNA_anti-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.3      0.63   1.3e+03      26      53 ..     225     251 ..     156     265 .. 0.76
   2 ?    9.2   1.8   0.00042      0.85      27      88 ..     329     390 ..     286     392 .. 0.83

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.63
                     XXXXXXXXXXXX---HHHHHTS-..... CS
  tRNA_anti-like  26 aqaaesardkekaekedadatlaeakak 53 
                     ++ a++++ + ka++e+a++++ + k +
      EEA22851.1 225 SKDASAVKTVIKAKEESAEKKA-PVKKE 251
                     4444455555555555555555.34443 PP

  == domain 2  score: 9.2 bits;  conditional E-value: 0.00042
                     XXXXXXXXXXX---HHHHHTS-..............EEEHHHHHHHHHH-HHHHHHHHTT-E CS
  tRNA_anti-like  27 qaaesardkekaekedadatlaeakakpeavaekasqisArdLlaeYdkNevkadkkYkGki 88 
                        ++a+++ k+e e+a a  +e+  k  +++e+a  ++A+++ +e++++ +k    Y  ki
      EEA22851.1 329 SLRADAEKAAKEEVEKAHALFDESAKKLMQQIEQARAAEAAQFREEFEAEREKLVRAYQEKI 390
                     4557788999999*************************************999888888776 PP

>> NAM-associated  No apical meristem-associated C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.5     0.015        30      90     118 ..     208     251 ..      39     278 .. 0.60
   2 ?    5.4   9.4     0.014        28      74     141 ..     328     398 ..     302     422 .. 0.79

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.015
  NAM-associated  90 e...............askdeealeklasaqkkiakkskekkee 118
                     +               askd+ a++ + +a++++a+k++  k+e
      EEA22851.1 208 DsasltqkgphnsavdASKDASAVKTVIKAKEESAEKKAPVKKE 251
                     03333334455555568899999999999999999998877766 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.014
  NAM-associated  74 rlkRPiGkkkaKekrke..askdeealeklasaqkkiakkskekkee.aeleekkldieeekveaeqrqae 141
                     ++ R    k+aKe  ++  a  de a++ +++ +++ a ++++ +ee ++++ek +++ +ek ++e ++a+
      EEA22851.1 328 SSLRADAEKAAKEEVEKahALFDESAKKLMQQIEQARAAEAAQFREEfEAEREKLVRAYQEKIQTELSRAQ 398
                     566778899****9999997788888888888888888888888888666778888888888888777665 PP

>> HisK_N  Histidine kinase N terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       1.2   2.4e+03      42      71 ..       6      35 ..       3      37 .. 0.85
   2 ?   -2.5   0.0       2.3   4.5e+03      57      75 ..     318     336 ..     314     346 .. 0.79
   3 ?    6.5   3.0    0.0038       7.6      53     114 ..     415     478 ..     353     482 .. 0.75

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 1.2
                HHHHHHHHHTTSS-GGGGHHHHHHHHHHHH CS
      HisK_N 42 lfelviellkeeiseedlkelaekiakeRv 71
                +++  ++ll+ + +    + la+ ia++R+
  EEA22851.1  6 VLSSQTRLLSASRQRTATQLLANPIASNRI 35
                66677889999999999**********997 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 2.3
                 GGGHHHHHHHHHHHHHHT- CS
      HisK_N  57 edlkelaekiakeRveanv 75 
                  +++++ +ki++ R++a+ 
  EEA22851.1 318 TEVETIGQKISSLRADAEK 336
                 5688899999999999875 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.0038
                 SS-GGGGHHHHHHHHHHHHHHT--THHHHHHHHHHHHHHHH..HHHCC---HHHHHHHHHHHHH CS
      HisK_N  53 eiseedlkelaekiakeRveanvnigdfvyNvnvgrsivlk..allklnvsldelqllidkine 114
                 e++ ++l+++ e + +eR    + i+++  Nvn   ++  +   ++++n+++++lq+++d + +
  EEA22851.1 415 ELNRKYLNDVKELVERERDGRLSKISELTANVNQLEKLTTDwsDVIESNLKTQQLQVAVDAVRS 478
                 3445569999999*********************999997522799*************99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (643 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2300  (0.128284); expected 358.6 (0.02)
Passed bias filter:                      729  (0.0406604); expected 358.6 (0.02)
Passed Vit filter:                        95  (0.00529868); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.86u 0.36s 00:00:01.22 Elapsed: 00:00:00.50
# Mc/sec: 3881.96
//
Query:       EEA22852.1  [L=218]
Description: RAB GTPase Ypt5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.5e-59  200.2   0.4    1.8e-59  200.0   0.4    1.0  1  Ras          Ras family
    1.3e-36  125.5   0.2    2.4e-36  124.6   0.1    1.5  2  Roc          Ras of Complex, Roc, domain of DAPkinase
    1.1e-14   54.2   0.0    1.4e-14   53.9   0.0    1.1  1  Arf          ADP-ribosylation factor family
    2.5e-07   30.5   0.0    3.5e-07   30.0   0.0    1.3  1  GTP_EFTU     Elongation factor Tu GTP binding domain
    5.9e-07   29.1   0.0    7.1e-07   28.8   0.0    1.1  1  Gtr1_RagA    Gtr1/RagA G protein conserved region
    8.6e-07   29.0   0.0    1.4e-06   28.4   0.0    1.3  1  MMR_HSR1     50S ribosome-binding GTPase
    2.1e-05   24.5   1.6       0.12   12.3   0.3    2.4  3  RsgA_GTPase  RsgA GTPase
  ------ inclusion threshold ------
      0.013   15.9   0.1      0.025   15.0   0.1    1.6  1  AAA_16       AAA ATPase domain
      0.051   13.9   0.1        2.7    8.3   0.0    2.3  2  AAA_22       AAA domain
      0.059   12.8   0.1       0.11   12.0   0.1    1.5  1  SRPRB        Signal recognition particle receptor beta subuni
       0.11   12.8   0.8        5.5    7.3   0.0    2.3  2  GbpA_2       N-acetylglucosamine binding protein domain 2
       0.13   11.9   0.0        4.7    7.0   0.0    2.4  2  Amidase02_C  N-acetylmuramoyl-l-alanine amidase


Domain annotation for each model (and alignments):
>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  200.0   0.4   1.2e-62   1.8e-59       1     160 [.      19     183 ..      19     185 .. 0.98

  Alignments for each domain:
  == domain 1  score: 200.0 bits;  conditional E-value: 1.2e-62
                 EEEEEESTTSSHHHHHHHHHHSSCSSSCTTTSSEEEEEEEEEET.TEEEEEEEEEETTSGGGHHHHHHHHTTESEEEEEEETTBHHHHHTHHHHHHHHH CS
         Ras   1 KlvlvGdsavGKtslllrfvkdkFkeeyesTigvdfytkeievd.gkevkleiwDTAGqeefkslrelyyrdaegillvyditsresfenvkkwveeik 98 
                 Klvl+G+savGK+sl+lrfvkd+F++  esTig++f+t++i++d +++vk+eiwDTAGqe++ksl+++yyr+a+++++vydit+++s++++k+wv+e++
  EEA22852.1  19 KLVLLGESAVGKSSLVLRFVKDQFDDYRESTIGAAFLTQTISLDeNTTVKFEIWDTAGQERYKSLAPMYYRNANCAVVVYDITQSASLDKAKSWVKELQ 117
                 99*****************************************97789*************************************************** PP

                 HHSTTTSEEEEEEETTTGGG....G-SS-HHHHHHHHHHHTSEEEEEBTTTTCTHHHHHHHHHHHH CS
         Ras  99 rvaeenvpivLvGnKvDlee....kravsteegeelakelglkfletSAktnenveeafeellrei 160
                 r+a+en+ i+L GnK Dl +    kra+ t+++e++ake gl f+etSAktn+nv+e+f+++++++
  EEA22852.1 118 RQANENIIIALAGNKLDLVTenpdKRAIATADAEAYAKEAGLLFFETSAKTNTNVKELFTAIAKKL 183
                 ******************988999**************************************9986 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  124.6   0.1   1.6e-39   2.4e-36       1     120 []      19     135 ..      19     135 .. 0.88
   2 ?   -2.6   0.0       4.2   6.3e+03      76     101 ..     153     178 ..     146     184 .. 0.59

  Alignments for each domain:
  == domain 1  score: 124.6 bits;  conditional E-value: 1.6e-39
                 EEEEESSTTSSHHHHHHCHCT-CCC-EEETTTTEEEEEEECGGSGGCTTBTTTTCEEEEEEEE-SGGCTTTT-HHHHCTSCEEEEEEEGHHH...HCHH CS
         Roc   1 KvvlvGdsgvGKtsllkrfvedkfsekekstigvdfltkevtkikgvendkkvkkvklniWDtaGqerfrslhplylreaalailvydsrss...enlk 96 
                 K+vl+G+s+vGK+sl+ rfv+d+f++ ++stig+ flt+++ ++++       ++vk++iWDtaGqer++sl+p+y+r+a++a++vyd ++s   +++k
  EEA22852.1  19 KLVLLGESAVGKSSLVLRFVKDQFDDYRESTIGAAFLTQTI-SLDE------NTTVKFEIWDTAGQERYKSLAPMYYRNANCAVVVYDITQSaslDKAK 110
                 99************************************987.3333......35799*******************************65542236789 PP

                 HHHHHHHHHCSSS-EE.EEEE-TTT CS
         Roc  97 eWlkelkkvagkspvi.lvgnkiDl 120
                 +W+kel+++a+++++i l gnk+Dl
  EEA22852.1 111 SWVKELQRQANENIIIaLAGNKLDL 135
                 9********99887664899***95 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 4.2
                 HHCTSCEEEEEEEGHHHHCHHHHHHH CS
         Roc  76 ylreaalailvydsrssenlkeWlke 101
                 y +ea l+++ + +++++n+ke ++ 
  EEA22852.1 153 YAKEAGLLFFETSAKTNTNVKELFTA 178
                 55555555555556666676665555 PP

>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.9   0.0   9.5e-18   1.4e-14      14     173 ..      17     181 ..      11     183 .. 0.86

  Alignments for each domain:
  == domain 1  score: 53.9 bits;  conditional E-value: 9.5e-18
                 EEEEEEEESTTSSHHHHHHHHHHSSCEE.CSSSSS..EEEEEEEE...TTEEEEEEEE-SSGGGGGGGGGGCTTESEEEEEEETT-CTTHHHHHHHHHH CS
         Arf  14 elrilllGLDnaGKtTilkklkleelvt.tvPTig..fnveelei...knlkftvwDvGGqeklRplWknYfektdavifvvDsadreRleeakeeLka 106
                 +++++llG  + GK+ ++ ++ ++++++    Tig  f +++++     ++kf++wD  Gqe+ ++l   Y+++ +  + v D +++  l++ak+ +k+
  EEA22852.1  17 QFKLVLLGESAVGKSSLVLRFVKDQFDDyRESTIGaaFLTQTISLdenTTVKFEIWDTAGQERYKSLAPMYYRNANCAVVVYDITQSASLDKAKSWVKE 115
                 789*********************99985678888334566666566678**********************************************999 PP

                 HCTSGCCTTSEEEEEEE-TTSTTSS-HHHHHHHTTGGGSSSSSSEEEEEEBTTTTBTHHHHHHHHHH CS
         Arf 107 lleeeelkevallvlaNKqDlpealseeelrellgleelkgkrkleiqkcsavkgeglkeglewlse 173
                 l +++ ++++++ + +NK Dl +   ++   ++ + e   ++  l  +++sa +++++ke ++ +++
  EEA22852.1 116 L-QRQANENIIIALAGNKLDLVTENPDKRAIATADAEAYAKEAGLLFFETSAKTNTNVKELFTAIAK 181
                 6.67789999999********9888777766666666666699999**************9998876 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.0   0.0   2.3e-10   3.5e-07      53     193 ..      51     184 ..      20     185 .. 0.76

  Alignments for each domain:
  == domain 1  score: 30.0 bits;  conditional E-value: 2.3e-10
                 TSCSSCEEEEEETTCSSEEEEEEEESSSGGGHHHHHHHHHT-SEEEEEEETTTB.....STHHHHHHHHHHHHTTTEEEEEEESCGSTHHHHHHHHHHH CS
    GTP_EFTU  53 giTiksaaisleketkkylinliDtPGHvdFskevirglrvlDgavlvvdaveG.....vepqteevlrlalkegvpiivfiNKmDrlkaelkeiveev 146
                 g    +++isl+ e ++ ++ + Dt G + + +     +r +++av+v d+++       ++  +e+ r+a+ e++ i ++ NK+D + ++ ++ + + 
  EEA22852.1  51 GAAFLTQTISLD-ENTTVKFEIWDTAGQERYKSLAPMYYRNANCAVVVYDITQSasldkAKSWVKELQRQAN-ENIIIALAGNKLDLVTENPDKRAIAT 147
                 334445566666.9999***********************************99443334444444444443.444466677******99999887776 PP

                 HHHHHHHHHHHHHHHHTTTTTEEEEEEBTTTTBTHHHHHHHHHHHSH CS
    GTP_EFTU 147 kqklsrkeeklekygekgekevpvvfgSalkgegvktllealvellp 193
                  +         e+y+ ++     ++ +Sa+++ +vk+l+ a+ ++lp
  EEA22852.1 148 ADA--------EAYAKEA--GLLFFETSAKTNTNVKELFTAIAKKLP 184
                 633........3444443..589*******************99987 PP

>> Gtr1_RagA  Gtr1/RagA G protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.8   0.0   4.7e-10   7.1e-07       1     145 [.      19     157 ..      19     183 .. 0.65

  Alignments for each domain:
  == domain 1  score: 28.8 bits;  conditional E-value: 4.7e-10
   Gtr1_RagA   1 kvLLmGksgsGKtsmr.siiFdnylardtlrlgatidveksevrflgnltlnlwDcgGqeafveeylssqkeeifrnvgvliyVfDvesreleedletl 98 
                 k++L+G+s  GK+s+  + + d++      ++ga+  ++  ++  +  +++++wD  Gqe++   +        +rn +  + V D++    + +l++ 
  EEA22852.1  19 KLVLLGESAVGKSSLVlRFVKDQFDDYRESTIGAAFLTQTISLDENTTVKFEIWDTAGQERYKSLA-----PMYYRNANCAVVVYDIT---QSASLDKA 109
                 899***********86234433333333344455555555555555569***********998775.....44455555555556998...44566667 PP

   Gtr1_RagA  99 keileal.rqyspeakvfvlihKmDliqedereeifeerkeeireeie 145
                 k+ +++l rq ++++ +    +K+Dl++e+  ++++ +  +e   + +
  EEA22852.1 110 KSWVKELqRQANENIIIALAGNKLDLVTENPDKRAIATADAEAYAKEA 157
                 777766625788889999999*******98877777666655544443 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.4   0.0   9.2e-10   1.4e-06       2     112 ..      20     128 ..      19     132 .. 0.75

  Alignments for each domain:
  == domain 1  score: 28.4 bits;  conditional E-value: 9.2e-10
                 EEEEESTTSSHHHHHHHHHTS.....TEEESSSTTSSSSEEEEEEEETTEEEEEEECGGCSSHHHHHHHHHHHHHHHHCTSEEEEEEETTTTCSHHHHH CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltge.....kaivsdkpgtTrdinegrvklkgkeielvDtpGliegaseekglgkaflaleeadlillvvdaseeklkplde 95 
                  +++G + vGKS+L+ + +++     +  +   ++ T++i   + +    ++e++Dt+G  e   + k+l+  + ++ ++ ++++ +  s ++l++ ++
  EEA22852.1  20 LVLLGESAVGKSSLVLRFVKDqfddyRESTIGAAFLTQTISLDENT--TVKFEIWDTAG-QE---RYKSLAPMYYRNANCAVVVYDITQS-ASLDKAKS 111
                 6899***************954444455666667888888777665..578********.54...5558888888877777766666644.56888888 PP

                 HHHHHHHHTTSEEEEEE CS
    MMR_HSR1  96 eleelleeakkplilvl 112
                  ++el+++a++++i++l
  EEA22852.1 112 WVKELQRQANENIIIAL 128
                 89999888888887765 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.2   0.1   0.00017      0.26     102     122 ..      20      40 ..      13      75 .. 0.81
   2 ?    1.2   0.0      0.21   3.1e+02      50      99 ..      66     115 ..      43     119 .. 0.72
   3 !   12.3   0.3     8e-05      0.12       4     100 ..      79     182 ..      76     185 .. 0.72

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00017
                  EEEECSTTSSHHHHHHHHCTT CS
  RsgA_GTPase 102 svlvGqSGvGKStLinallpe 122
                   vl+G+S vGKS+L+ +++ +
   EEA22852.1  20 LVLLGESAVGKSSLVLRFVKD 40 
                  79************9877665 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.21
                  EEEEE-GGG--HHHHHHHHHHHHHHTTSEEEE--TTTHTTHHHHHHHCTT CS
  RsgA_GTPase  50 vivlnKiDlleeeeeleelkeelealgyevllvsaktkegleelkellkd 99 
                  ++ +   D + +e+  +     +++++++v++ + +++++l++ k+++k+
   EEA22852.1  66 TVKFEIWDTAGQERYKSLAPMYYRNANCAVVVYDITQSASLDKAKSWVKE 115
                  55555566666666333344568999999999999999999999998876 PP

  == domain 3  score: 12.3 bits;  conditional E-value: 8e-05
                  -S-EETTTTEES--EEEEEEESTTTT--HHHHH...HHHHHHHHTT-EEEEEEE-GGG--HHH.....HHHHHHHHHHHTTSEEEE--TTTHTTHHHH CS
  RsgA_GTPase   4 RknelvrpkvaNvdqllivvslkepelslnlld...rfLvlaeekgiepvivlnKiDlleeee.....eleelkeelealgyevllvsaktkegleel 93 
                  R ++l      N + +++v  ++ ++ sl+  +   + L    +++i + ++ nK+Dl++e+      ++ + ++  +++g+ ++ +sakt+++++el
   EEA22852.1  79 RYKSLAPMYYRNANCAVVVYDIT-QSASLDKAKswvKELQRQANENIIIALAGNKLDLVTENPdkraiATADAEAYAKEAGLLFFETSAKTNTNVKEL 175
                  55555555566777778887777.45555444411145555666677777777*******99988876666777778899****************** PP

                  HHHCTTS CS
  RsgA_GTPase  94 kellkdk 100
                   +++++k
   EEA22852.1 176 FTAIAKK 182
                  9999886 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.0   0.1   1.7e-05     0.025      27     107 ..      20     100 ..      17     198 .. 0.63

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.7e-05
      AAA_16  27 vllsGesGvGKsslvrellralekdggiflrgkcdqlesaipysalaqalareellrqlldeaesaeleawrekleeala..................a 107
                 ++l Ges+vGKsslv ++ +            ++d+++++    ++  a+ + + +   lde ++ ++e w+++ +e+++                  +
  EEA22852.1  20 LVLLGESAVGKSSLVLRFVK-----------DQFDDYRES----TIGAAFLT-QTI--SLDENTTVKFEIWDTAGQERYKslapmyyrnancavvvydI 100
                 5799***********55554...........345555222....23333322.221..22233344555555555555554444444444444444441 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   0.0    0.0018       2.7       8      38 ..      20      62 ..      16     135 .. 0.73
   2 ?    3.9   0.0      0.04        59      37      70 ..     148     189 ..     103     207 .. 0.77

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.0018
      AAA_22  8 lvvtGesGtGKTtl.lrrlleqldeeakaee...........e 38
                lv+ Ges +GK+ l lr +++q+d + + +             
  EEA22852.1 20 LVLLGESAVGKSSLvLRFVKDQFDDYRESTIgaafltqtislD 62
                6899*******87615566677776655555555555555553 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.04
      AAA_22  37 e......erpevvfvtlpsst..sskdllrellralglelka 70 
                        ++++++f++ +++t  + k+l+++++++l l++ +
  EEA22852.1 148 AdaeayaKEAGLLFFETSAKTntNVKELFTAIAKKLPLDQAG 189
                 25556667888889999999988************9998877 PP

>> SRPRB  Signal recognition particle receptor beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.1   7.1e-05      0.11       5     131 ..      19     142 ..      16     181 .. 0.70

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 7.1e-05
                 EEEEE-STTSSHHHHHHHHHHSS---B---S..S-EEETTG.....GGTT-SEEEETT-GCCSHHHHHHHHHHGGEEEEEEEEETTS-HHHHHHHHHHH CS
       SRPRB   5 avllvGlsdsGKTslftrLttdsvkktvtSq..essaalkv..ksekgskltliDfPGheklrqklleklkaksslkglvfvvDStidpkevkevAEll 99 
                 +++l+G s  GK sl  r  +d++ +   S   ++ +++ +  +++   k+++ D  G+e+ ++ l   +  +++   +v+ +  ++      + A   
  EEA22852.1  19 KLVLLGESAVGKSSLVLRFVKDQFDDYRESTigAAFLTQTIslDENTTVKFEIWDTAGQERYKS-LAPMYYRNANCAVVVYDITQSA----SLDKAKSW 112
                 57899*****************988888887544445555544677788999********9865.4554344444555555443333....33333333 PP

                 HHHHHHHHHHTT---EEEEEE-TTSTT---HH CS
       SRPRB 100 yeilliteklkdavdiliACnKqelflakspk 131
                 ++ l  +  +++++ i +A nK +l++  ++k
  EEA22852.1 113 VKELQRQ--ANENIIIALAGNKLDLVTENPDK 142
                 3333333..35677777888888877766654 PP

>> GbpA_2  N-acetylglucosamine binding protein domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.3   0.0    0.0037       5.5       7      34 ..      55      82 ..      50      95 .. 0.83
   2 ?    3.7   0.4      0.05        74      37      69 ..      99     131 ..      89     150 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.3 bits;  conditional E-value: 0.0037
                E---S---TT-EEEEEEEETTEE-GGG- CS
      GbpA_2  7 vtptqdlkaGdtvtlrvfdangeelele 34
                +t+t  l +++tv+++++d+ g+e+ ++
  EEA22852.1 55 LTQTISLDENTTVKFEIWDTAGQERYKS 82
                567799*****************98765 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.05
                 EE--SCGGGSHHHHHHHHHHHHHHH-SSEEESE CS
      GbpA_2  37 liiasaaegkaanWayaLAqkiNaesslvraGv 69 
                  i++sa+  ka+ W ++L ++ N++   + aG 
  EEA22852.1  99 DITQSASLDKAKSWVKELQRQANENIIIALAGN 131
                 57899999*************999877777776 PP

>> Amidase02_C  N-acetylmuramoyl-l-alanine amidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.0   0.0    0.0032       4.7      21      35 ..      99     113 ..      95     115 .. 0.88
   2 ?    2.2   0.0     0.098   1.5e+02      12      29 ..     155     173 ..     149     178 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0032
  Amidase02_C  21 eptsdteLdkitawL 35 
                  + t+++ Ldk+++w 
   EEA22852.1  99 DITQSASLDKAKSWV 113
                  899***********5 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.098
  Amidase02_C  12 pd.GltYfiTeptsdteLd 29 
                  ++ Gl +f+T    +t+ +
   EEA22852.1 155 KEaGLLFFETSAKTNTNVK 173
                  445***********99987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (218 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       569  (0.0317363); expected 358.6 (0.02)
Passed bias filter:                      450  (0.025099); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 1543.41
//
Query:       EEA22853.1  [L=707]
Description: phosphoinositide phosphatase (Sac1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-91  306.2   0.1    3.6e-91  305.8   0.1    1.1  1  Syja_N    SacI homology domain


Domain annotation for each model (and alignments):
>> Syja_N  SacI homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  305.8   0.1     2e-95   3.6e-91       2     320 .]      60     408 ..      59     408 .. 0.91

  Alignments for each domain:
  == domain 1  score: 305.8 bits;  conditional E-value: 2e-95
      Syja_N   2 gilGlirllsgsyllvitkreevgtlkgkkeiykitevellplsseeeaekalkslkaktekkkeekeleekllklleklfessgsfYFsydlDltrsl 100
                 gilG+i+l+ ++y++vitk++ +g+l+g+ ++yk+ ++e+lpl++       l+            +++e+++l+ll k + ++g +YFsy+lDlt+++
  EEA22853.1  60 GILGIIKLKLDKYIIVITKAQPMGRLQGH-MVYKVVATEFLPLRER-----PLH------------DKDEDTYLALL-KDLIRTGPMYFSYSLDLTNTF 139
                 9********99***************886.************9433.....222............335899*****.55558**************** PP

      Syja_N 101 qrqlekssesskslplweraderFvWNrhllkpli..............ea..eldswllpviqGfveqsklklsksqkekekkevtltlisRrsrkra 183
                 qrq++    s++s+plw+rad+rF+WNr+++++li              ++  ++d ++lpvi G+++ +  +       ++++++t++li+Rrsr+r 
  EEA22853.1 140 QRQSQ----SDPSTPLWKRADDRFFWNRFIQSDLIdfrvgssdttgtkyNQqpGVDPYILPVIFGMLRITPAR-------VKNTSFTFALITRRSRHRG 227
                 ***98....589999******************99888888877776651167**************444443.......45688************** PP

      Syja_N 184 GtRylrRGiddeGnvANfvEtEqileves.....................sekeskilSfvqiRGSiPlfWsqeptlkykpkirierseeenleafkkH 261
                 GtRy++RGid++Gnv+N+ EtEqi+  ++                       ++ ++++fvq+RGS+P+fWs+ ++l+y+pk+++ rs e++ ea++kH
  EEA22853.1 228 GTRYFSRGIDENGNVSNYNETEQIVILNDttggltgfaggqglpsgkseqPGRDLQVFAFVQTRGSVPVFWSEVNNLRYTPKLQV-RSVETSIEAAQKH 325
                 **************************7778******************98556679*****************************.6************ PP

      Syja_N 262 fekllkrYgkvvvvnLlekkgrEkkLgeayekavkklnkle........................kekkklkyveFDfhkeck 320
                 f ++++ Yg+ ++vnL+++kgrE+++++aye++v++l +++                        +  ++++y++FDfh+e+k
  EEA22853.1 326 FAQQIQYYGENYLVNLVNHKGREERVKKAYEQLVRTLVSSPgetseqdqphtdekirtvesaqrkELLDRIHYIYFDFHNETK 408
                 *************************************974479*******************9997779************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (707 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       553  (0.0308439); expected 358.6 (0.02)
Passed bias filter:                      466  (0.0259914); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.45
# Mc/sec: 4698.74
//
Query:       EEA22854.1  [L=506]
Description: tetrahydrofolylpolyglutamate synthase (Met7), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.9e-05   24.1   0.4    0.00048   20.2   0.4    2.7  1  Mur_ligase_M  Mur ligase middle domain


Domain annotation for each model (and alignments):
>> Mur_ligase_M  Mur ligase middle domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.4   2.7e-08   0.00048       1     104 [.      63     226 ..      63     289 .. 0.82

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 2.7e-08
                   EESSS-HHHHHHHHHHHHHCT..EEEEETTC...........................................................SS-THHH CS
  Mur_ligase_M   1 vTGtnGKTTtteliaaileka..gkvigtvg...........................................................ttnneig 36 
                   ++Gt+GK +t+ +i +il++   g   +tv                                                             +   ++
    EEA22854.1  63 IAGTKGKGSTSAFISSILNQYigGTDQATVHkvglytsphlrfarerikindeplteaqfaryffevwdrleqsakaaghqnpsspetkpVYFRYLT 159
                   89****************9998744555555677999************************************************997776666677 PP

                   HHHHHHHHHHTT-SEEEEE--HCHHHCTTTCCH.CBESEEEE---TSTTHHHH.SSHHHHHHHHHHHHHT CS
  Mur_ligase_M  37 lpktlaemekkeaeyavlEvsshglgekrlegl.lkpdvavitnispdHldfh.gtlenyaeaKaelfer 104
                   l ++ a + + ++++av+E +    ge    ++  +p v  it+++ dH+  + +t+e++a  K  +++ 
    EEA22854.1 160 LMALHAYLSE-GVDAAVIECGIG--GEYDSTNIiDQPVVSGITSLGIDHVAMLgSTIEEIAWHKGGIIKT 226
                   7776666677.************..55333333258***************99789********999984 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (506 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       456  (0.0254337); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 3566.17
//
Query:       EEA22855.1  [L=534]
Description: peptide N-myristoyl transferase (Nmt1) [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.5e-88  295.8   0.0    2.6e-88  295.0   0.0    1.4  1  NMT_C            Myristoyl-CoA:protein N-myristoyltransferase
    8.3e-75  250.0   0.2    9.5e-74  246.6   0.0    2.1  2  NMT              Myristoyl-CoA:protein N-myristoyltransferase
    7.8e-06   26.0   0.1    0.00026   21.1   0.0    2.3  2  Acetyltransf_9   Acetyltransferase (GNAT) domain
    0.00067   19.9   0.0     0.0015   18.7   0.0    1.7  1  Acetyltransf_1   Acetyltransferase (GNAT) family
  ------ inclusion threshold ------
      0.012   15.5   0.1      0.039   13.8   0.0    1.9  2  NTP_transf_9     Domain of unknown function (DUF427)
      0.035   14.4   0.0      0.069   13.5   0.0    1.5  1  DUF5024          Domain of unknown function (DUF5024)
      0.075   13.0   0.0       0.16   11.9   0.0    1.5  1  Acetyltransf_10  Acetyltransferase (GNAT) domain


Domain annotation for each model (and alignments):
>> NMT_C  Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  295.0   0.0     1e-91   2.6e-88       1     209 []     318     532 ..     318     532 .. 0.95

  Alignments for each domain:
  == domain 1  score: 295.0 bits;  conditional E-value: 1e-91
                 HTTSS--BTTS-HHHHHHHH---SS-SSTTEEE--CCCHHHHHHHHHHHHTTSSEEEE--HHHHHHHHC-SSTTSBTTTEEEEEEEETTS.EEEEEEEE CS
       NMT_C   1 evgFsalprnstlarlvklyklpeetktkglremeekDveavtellekylkrfdlaqvfseeeveHwllskkkkreeqvvwsYVvedeetkkitDfvSF 99 
                 evgFs+lp++st+ar++++++lp++t+t+glr++++kD++a  +lle++++rf++ ++f++ee+eHwll+ +++r eqvvwsYVved++tkkitDfvSF
  EEA22855.1 318 EVGFSPLPAGSTKARQITKNHLPSSTATPGLRKLQKKDLDATYDLLERFQSRFQVNPAFTKEEIEHWLLH-TEARGEQVVWSYVVEDPQTKKITDFVSF 415
                 79********************************************************************.77999*********************** PP

                 EE--EEETT-SS-SEEEEEEEEEEEECCC.....TTHHHHHHHHHHHHHHHHHHCTESEEEEESSTTGGGCTTTTT-EEEEEEEEEEEETEEE.-..-S CS
       NMT_C 100 YslpstvlknpkhktlkaAYlfyyastet.....kklkkrlkeLvkdalilakkakfDvfnaltlmdnklfleelkFgagdgkLnYYLyNyrvapiagg 193
                 Ysl+s+v++npkhk ++aAYl+yya+++      k  k+rl+ Lv+dali akka+fDvfnaltl+dn+lfle+lkFgagdg+L+YYLyNyr+ap+ gg
  EEA22855.1 416 YSLESSVIGNPKHKAVRAAYLYYYATETAfnekeKGFKERLQLLVNDALIEAKKARFDVFNALTLQDNPLFLEQLKFGAGDGQLHYYLYNYRTAPVPGG 514
                 *************************55554444488999************************************************************ PP

                 B-CCGSB.TT....BEXX CS
       NMT_C 194 vkeekeleekkg..vGvv 209
                 v++++  +ekk+  +Gvv
  EEA22855.1 515 VNDKNLPDEKKRggMGVV 532
                 ****99996665578887 PP

>> NMT  Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  246.6   0.0   3.7e-77   9.5e-74       6     160 .]     150     304 ..     146     304 .. 0.98
   2 ?    1.3   0.0      0.11   2.8e+02      57     101 ..     375     422 ..     339     439 .. 0.67

  Alignments for each domain:
  == domain 1  score: 246.6 bits;  conditional E-value: 3.7e-77
                 --GGGS-SS----STTEEEEE--TTSHHHHHHHHHHHHHHSSCTTTSTEEE---HHHHHHHCTSTT--GGGEEEEEETTTTEEEEEEEEEEEEEEETTE CS
         NMT   6 kkveevrkeplklpkgfewvtvdledeeelkevyelLsenYvedddamfrfkyskeflkWalkppgykkewhvgvrvkkskkLvafisaipvklrvrkk 104
                  ++eev+kep +l++gfewvt+d+ed++e+ e+yelLs++Yvedd+amfrf+ys+ fl+Wal++pg+kk+whvgvr++ks+kLva i+++p+ +rvr++
  EEA22855.1 150 INPEEVSKEPPQLIEGFEWVTLDVEDDKEVAELYELLSNHYVEDDNAMFRFNYSRAFLNWALTSPGWKKDWHVGVRASKSGKLVASICGVPTYIRVRDQ 248
                 5689*********************************************************************************************** PP

                 EEEEEEEEEEEE-GGGTTSSHHHHHHHHHHHHHHTTT--EEEEEESSTSSSESEEE CS
         NMT 105 vlklveinfLcvhkklRskrlapvlikEitRrvnlkgifqavytagvvlpkpvstC 160
                  lk+ einfLcvhkklRskrlapvlikE+tRr+ l+gi+qa+yt g+vlpkpv++C
  EEA22855.1 249 RLKVIEINFLCVHKKLRSKRLAPVLIKEVTRRCYLQGIYQAIYTVGIVLPKPVTSC 304
                 *******************************************************9 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.11
                 ---HHHH.HHHCTS..TT--GGGEEEEEETTTTEEEEEEEEEEEEEEE CS
         NMT  57 kyskefl.kWalkp..pgykkewhvgvrvkkskkLvafisaipvklrv 101
                 +++ke + +W l++   g +  w   v   ++kk+  f+s   ++ +v
  EEA22855.1 375 AFTKEEIeHWLLHTeaRGEQVVWSYVVEDPQTKKITDFVSFYSLESSV 422
                 45554442688875115677889***************9977776666 PP

>> Acetyltransf_9  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.1   0.0     1e-07   0.00026      15     107 ..     184     286 ..     173     311 .. 0.82
   2 ?    2.6   0.1     0.052   1.3e+02       2      48 ..     348     398 ..     347     456 .. 0.71

  Alignments for each domain:
  == domain 1  score: 21.1 bits;  conditional E-value: 1e-07
                     HHHHHHTT----H..........HHHHHHHHHHTTSEEEEEEE..TTEEEEEEEEEEEEEEETTEEEEEEEEEEEEE-CCGTTS-HHHHHHHHHH CS
  Acetyltransf_9  15 ellkyaFqdeespl.......e.eireyfrklleesrvlgaed..ngelvgqlallplelnvpGktlkaagvtgVavapehrgrgvlskLlaral 99 
                     ell+  + +++++            ++  ++  ++++++g++    g+lv++++ +p  ++v++++lk+  +   +v+ + r + ++  L++++ 
      EEA22855.1 184 ELLSNHYVEDDNAMfrfnysrAfLNWALTSPGWKKDWHVGVRAskSGKLVASICGVPTYIRVRDQRLKVIEINFLCVHKKLRSKRLAPVLIKEVT 278
                     5555555555555555555443346889999999******99888************************************************** PP

                     HHHHHTT- CS
  Acetyltransf_9 100 eemreegq 107
                     ++++ +g+
      EEA22855.1 279 RRCYLQGI 286
                     99998776 PP

  == domain 2  score: 2.6 bits;  conditional E-value: 0.052
                     EEEE-GGGHHHHHHHHHHHTT----H......HHHHHHHHHHTTSEEEEEE CS
  Acetyltransf_9   2 irelteedldevlellkyaFqdeespl...e.eireyfrklleesrvlgae 48 
                     +r+l+++dld+ ++ll++   + +      + ei+ ++  +  +++ +++ 
      EEA22855.1 348 LRKLQKKDLDATYDLLERFQSRFQVNPaftKeEIEHWLLHTEARGEQVVWS 398
                     699************998654443333445557777777776666555554 PP

>> Acetyltransf_1  Acetyltransferase (GNAT) family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0     6e-07    0.0015      37     114 ..     224     309 ..     180     313 .. 0.80

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 6e-07
                     E.EEETTEEEEEEEEEEEET....TSTTEEEEEEEEESGGGTTSSHHHHHHHHHHHHHHHTTE.SEEEE..EEETTEHHHHHHHHH CS
  Acetyltransf_1  37 v.aeedgeliGfisllkipd....ekggvayieslaVspeyrgkGlGsaLlealeerareegi.kkivl..aveedndaairlYek 114
                     v a++ g+l++ i++ + +     ++ +v++i++l V+++ r k l+  L++++ +r+  +gi ++i+    v +  + ++r+Y +
      EEA22855.1 224 VrASKSGKLVASICGVPTYIrvrdQRLKVIEINFLCVHKKLRSKRLAPVLIKEVTRRCYLQGIyQAIYTvgIVLPKPVTSCRYYHR 309
                     2477889******99998888999889************************************99996655555557788888866 PP

>> NTP_transf_9  Domain of unknown function (DUF427)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       3.2   8.1e+03      51      65 ..       7      21 ..       5      31 .. 0.74
   2 ?   13.8   0.0   1.5e-05     0.039      52      91 ..     378     416 ..     356     418 .. 0.86

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 3.2
                  TTEEEEEEEEEETTE CS
  NTP_transf_9 51 wKGeasyyslavdgk 65
                   KG+a+  +++ d+ 
    EEA22855.1  7 SKGKARVQDVTDDNA 21
                  699999999986655 PP

  == domain 2  score: 13.8 bits;  conditional E-value: 1.5e-05
                   TEEEEEEEEEETTEEEEEEEEEESS--TT-GGGTT-BEE- CS
  NTP_transf_9  52 KGeasyyslavdgkevkdaaWsYpeptpeaaeikgyvaFy 91 
                   K e + + l++ + + ++++WsY    p+ ++i ++v+Fy
    EEA22855.1 378 KEEIEHWLLHT-EARGEQVVWSYVVEDPQTKKITDFVSFY 416
                   77788888874.4569***********************9 PP

>> DUF5024  Domain of unknown function (DUF5024)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   2.7e-05     0.069       3      55 ..     380     432 ..     378     470 .. 0.80

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 2.7e-05
     DUF5024   3 nidklverlesrkdvaitsvtkrdPkTrkVvkvVksfsvkdeglgkelkeAFe 55 
                 +i++ + + e+r++  + s ++ dP+T+k++  V+ +s++ + +g+  ++A +
  EEA22855.1 380 EIEHWLLHTEARGEQVVWSYVVEDPQTKKITDFVSFYSLESSVIGNPKHKAVR 432
                 567777778888888899999*******************9999987777766 PP

>> Acetyltransf_10  Acetyltransferase (GNAT) domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.0   6.2e-05      0.16      45      85 ..     242     286 ..     217     294 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 6.2e-05
  Acetyltransf_10  45 vielrdgs....hisllfVdpeyrgqGigkaLleaveeeaekdgi 85 
                      +i++rd++    +i  l+V+++ r++ ++  L+++v +++  +gi
       EEA22855.1 242 YIRVRDQRlkviEINFLCVHKKLRSKRLAPVLIKEVTRRCYLQGI 286
                      568877779999***************************977765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (534 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       874  (0.0487478); expected 358.6 (0.02)
Passed bias filter:                      695  (0.038764); expected 358.6 (0.02)
Passed Vit filter:                        67  (0.00373696); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.67u 0.31s 00:00:00.98 Elapsed: 00:00:00.49
# Mc/sec: 3271.60
//
Query:       EEA22856.1  [L=689]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.8e-19   68.5   0.0    1.5e-18   67.4   0.0    1.6  1  TLD       TLD
  ------ inclusion threshold ------
      0.062   14.3   1.4       0.25   12.4   1.2    2.2  2  DUF1773   Domain of unknown function


Domain annotation for each model (and alignments):
>> TLD  TLD
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.4   0.0   1.7e-22   1.5e-18       2     138 ..     396     612 ..     395     613 .. 0.90

  Alignments for each domain:
  == domain 1  score: 67.4 bits;  conditional E-value: 1.7e-22
         TLD   2 lyssskdgsslstllekie.nkgptllli.........kdekkyifGaflsqpw.......kssnkkfygdsesflfslspkfkvykstgkn....... 76 
                 ++s+ ++g+sl+++ +++  +++p +l++         + ++  ++Ga+++qpw       + s++ + ++   +lf+++pk+ v+ ++++        
  EEA22856.1 396 VFSTVAHGESLTSFQHNVFtWQAPSILIVqgaapgssgTPDELITLGAYIPQPWkpsssswETSQSLNDKSRLPYLFQIHPKHSVLPGNPSLlstreqs 494
                 7*****************99**************9998555559**********77766664444456666899**************77777777778 PP

         TLD  77 .....kaylntssdglgfGggqp.............................................kfsLwidsslekgtsrhs......etfe... 116
                      ++y++t++ g+++G+++p                                             + sL+ids le+++ + s      ++f    
  EEA22856.1 495 sattpTVYFSTTT-GIAIGCEIPasaqqqrthygpgvpsprehlqhhrqssggnsihkqqqqgpiphgAGSLIIDSGLETAQLHISyltgstGVFTrav 592
                 8999899999999.************************************************************************9999998888666 PP

         TLD 117 ngllsgaseerfkikdiEVWgl 138
                 +++l+  ++++++i+++E+Wg+
  EEA22856.1 593 PPILP--TTTHIDIYNLEIWGI 612
                 67777..9************97 PP

>> DUF1773  Domain of unknown function
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   1.2   2.8e-05      0.25       1      56 [.     315     378 ..     315     379 .. 0.63
   2 ?   -2.9   0.0       1.7   1.5e+04      34      43 ..     593     602 ..     579     607 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 2.8e-05
     DUF1773   1 hflfsknldfskrksgysassvpflngeepedee.....PL.Lpdigs..ilDinvLSQlsfFL 56 
                 h lfsknld+s++++g s  s +++++++ + +e      + Lp + +  il  +  S lsfFL
  EEA22856.1 315 HLLFSKNLDLSRKQTGASNASPESHPPIQTPINEeeqptTImLPGSFEsaILTPSLVSHLSFFL 378
                 99************99998888888777664444456331235544322255555555566555 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 1.7
     DUF1773  34 ePLLpdigsi 43 
                 +P+Lp+++ i
  EEA22856.1 593 PPILPTTTHI 602
                 3999998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (689 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       356  (0.0198561); expected 358.6 (0.02)
Passed bias filter:                      296  (0.0165096); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.26s 00:00:00.90 Elapsed: 00:00:00.46
# Mc/sec: 4548.38
//
Query:       EEA22857.1  [L=846]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (846 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1535  (0.0856155); expected 358.6 (0.02)
Passed bias filter:                      625  (0.0348597); expected 358.6 (0.02)
Passed Vit filter:                       128  (0.00713927); expected 17.9 (0.001)
Passed Fwd filter:                        61  (0.00340231); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 1.65u 0.34s 00:00:01.99 Elapsed: 00:00:00.57
# Mc/sec: 4485.10
//
Query:       EEA22858.1  [L=429]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.6e-08   33.2   0.0    1.1e-07   32.6   0.0    1.4  1  Abhydrolase_6  Alpha/beta hydrolase family
    2.8e-05   23.5   0.0    0.00011   21.5   0.0    2.0  1  Hydrolase_4    Serine aminopeptidase, S33
     0.0016   18.1   0.1     0.0077   15.9   0.0    2.1  2  Abhydrolase_1  alpha/beta hydrolase fold
  ------ inclusion threshold ------
       0.14   12.0   0.0       0.22   11.4   0.0    1.4  1  Abhydrolase_3  alpha/beta hydrolase fold


Domain annotation for each model (and alignments):
>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.6   0.0   2.5e-11   1.1e-07       2     184 ..     127     335 ..     125     410 .. 0.61

  Alignments for each domain:
  == domain 1  score: 32.6 bits;  conditional E-value: 2.5e-11
                    EEE--GC......GCHHHHHHHHCCTC.......EEEEE--TTSTS-GGCS--HHHCHHHHHHHCCTT.......TTSEEEEEETCHHHHHHHHHH CS
  Abhydrolase_6   2 lllHGagss.assWlvapLaallaagv.......hvlapDlpGhGrsdpppldledladlaalldelaa.....gggpvvlvGHSlGGalalaaap 84 
                    +  HG  ++ +s+   +p+ ++ a+gv       hv+a+D++G+G+s++ p++   + d + ll+ l +     ++ ++v  G SlG+a+ +a   
     EEA22858.1 127 VTFHGNAGHlGSM--IRPVMYRMASGVstpenplHVFAIDYRGYGFSTGNPTEEGVITDGVTLLNFLTSdpfniSPSRIVMTGLSLGTAITSA--- 217
                    5568844331222..336666667774444444499*********9988887776666666666666666669999999**********9999... PP

                    CC.......................EE.EEES-...............----TTTS----TTHHHHHHTT-CCCCHCCHS-HSCCCCHHHCCCCHC CS
  Abhydrolase_6  85 la.....................lvvg.vlldp....pp.........talpagllaaalelllallallrllawlsreplprlfladedadaawr 145
                    +a                     + +g +l+++    p+         +++p++ +   ++++++++++ +                      +w 
     EEA22858.1 218 VAerfafgapetatvqpaladpePFAGiILVASfsniPGlvesysfkgLTPPMLSPFNSFPQAQTWIKSQII--------------------DTWK 293
                    554434555554444444444443334344444333311223333332233333333333333344443333....................4444 PP

                    HCCCGHHHHCCHHCHTTCCHHTT-TTGC...EEECTT-CHHH CS
  Abhydrolase_6 146 arlarlaallaglgllpaaawadlpvpl...lvlggeDplvp 184
                     + + ++ + +++ ++  a+++++  ++   ++++ +D+ +p
     EEA22858.1 294 SNARLARLTGMKPKENDEADIRHAQKAVditIIHARNDAEIP 335
                    444444444445555555555555555544222245554444 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.5   0.0   2.5e-08   0.00011       3     117 ..     122     258 ..     120     332 .. 0.71

  Alignments for each domain:
  == domain 1  score: 21.5 bits;  conditional E-value: 2.5e-08
  Hydrolase_4   3 pkavvvlvHGlaehsgryae.laeaLa......aqGfavyalDhrGhGrsegkrghvpsfddyvdDlaafvekvk.eehpel..plfllGhSmGGlia 90 
                  +  vvv +HG a h g + + +++++a      ++  +v+a+D+rG+G s g+       + +++D  ++++ +  ++ + +  ++++ G S+G +i+
   EEA22858.1 122 HSRVVVTFHGNAGHLGSMIRpVMYRMAsgvstpENPLHVFAIDYRGYGFSTGNPT----EEGVITDGVTLLNFLTsDPFNISpsRIVMTGLSLGTAIT 215
                  6789************9999788888844444457899************88877....889999999999999944444447789************ PP

  Hydrolase_4  91 llyl................lrypdkvaglilsaPalkikakl 117
                   +++                l  p+ +ag+il+a++ +i+  +
   EEA22858.1 216 SAVAerfafgapetatvqpaLADPEPFAGIILVASFSNIPGLV 258
                  9999555555554444443333444666666666666666544 PP

>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   0.0      0.22   9.9e+02      87     125 ..      24      61 ..      22      66 .. 0.87
   2 !   15.9   0.0   1.7e-06    0.0077       2      95 ..     125     227 ..     124     280 .. 0.75

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.22
                    HHHHHHHHGGGEEEEEEESECSSCCHHHHHHHHHHHHHH CS
  Abhydrolase_1  87 alayaaeyperVkalvllgaidpaaslieaqrqqaksfp 125
                    ++ ya  yp   +a+v ++  +++a + ++++  +++f 
     EEA22858.1  24 SWLYAMTYPGLQRAMVYMNF-ANPAIWQDLNDVEIFGFL 61 
                    899***************99.999999999988888776 PP

  == domain 2  score: 15.9 bits;  conditional E-value: 1.7e-06
                    EEEEE-STTTCGGG.....GTTGHHHHHHHHT..TSEEEEEEETTSTTSSSTTTGB.CHHSHHHHHHHHHHH.HHHCTTS..SEEEEEETHHHHHH CS
  Abhydrolase_1   2 vlvilhGlpgssdv.....waerglapaLakd..gfdvillDlrGvgySspapacinddygtasvaddldri.ldalgdd..kltlvGhSmGGmia 87 
                    v+v +hG +g +++      ++  +a++ +      +v+++D rG+g+S+  p++   +  + +    l+++  d++++   ++++ G S+G++i 
     EEA22858.1 125 VVVTFHGNAGHLGSmirpvMYR--MASGVSTPenPLHVFAIDYRGYGFSTGNPTE---EGVITDGVTLLNFLtSDPFNISpsRIVMTGLSLGTAIT 215
                    6888999999666655666556..4444444455999****************95...444445777888889898887522799*********** PP

                    HHHHHHH....G CS
  Abhydrolase_1  88 layaaey....p 95 
                    +a+a+++    p
     EEA22858.1 216 SAVAERFafgaP 227
                    ******977662 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   4.8e-05      0.22      48      94 ..     180     224 ..     126     284 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 4.8e-05
                    HHHHHHHHHHHHHHTHHHHTETTCEEEEEEETHHHHHHHHHHHHHHH CS
  Abhydrolase_3  48 avedalaalrwlaeqawelgadpsrivlaGdSaGGnlaaavalrard 94 
                     + d+++ l+ l +    +++ psriv+ G S G  ++ ava r++ 
     EEA22858.1 180 VITDGVTLLNFLTSD--PFNISPSRIVMTGLSLGTAITSAVAERFAF 224
                    578999999999999..69***********************88764 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (429 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       315  (0.0175693); expected 358.6 (0.02)
Passed bias filter:                      273  (0.0152267); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.46
# Mc/sec: 2827.55
//
Query:       EEA22859.1  [L=803]
Description: translation elongation factor G1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    3.2e-57  193.2   0.1    5.2e-57  192.5   0.1    1.4  1  GTP_EFTU     Elongation factor Tu GTP binding domain
    4.6e-34  116.3   0.0      1e-33  115.3   0.0    1.6  1  EFG_II       Elongation Factor G, domain II
    5.3e-34  116.6   0.0      1e-33  115.7   0.0    1.5  1  EFG_IV       Elongation factor G, domain IV
      2e-22   79.0   0.0    4.3e-22   77.9   0.0    1.6  1  EFG_C        Elongation factor G C-terminus
    3.9e-13   49.6   0.1    8.5e-13   48.5   0.1    1.6  1  GTP_EFTU_D2  Elongation factor Tu domain 2
    7.3e-07   29.1   0.1    2.2e-06   27.5   0.0    1.9  2  RF3_C        Class II release factor RF3, C-terminal domain
  ------ inclusion threshold ------
      0.014   15.2   0.1      0.043   13.6   0.1    1.9  1  ATP_bind_1   Conserved hypothetical ATP binding protein
      0.067   13.3   0.0       0.92    9.6   0.0    2.7  2  DUF442       Putative phosphatase (DUF442)
       0.11   12.5   0.0       0.24   11.5   0.0    1.6  1  MMR_HSR1     50S ribosome-binding GTPase


Domain annotation for each model (and alignments):
>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  192.5   0.1   2.6e-60   5.2e-57       2     193 ..     103     385 ..     102     386 .. 0.90

  Alignments for each domain:
  == domain 1  score: 192.5 bits;  conditional E-value: 2.6e-60
                 CEEEEEEEESTTSSHHHHHHHHHHHTTSSCHHHHHHHHHST...HCHSHHHHHHTSCSSCEEEEEE.....T.TCSSEEEEEEEESSSGGGHHHHHHHH CS
    GTP_EFTU   2 rirnigiighvDhGKtTLtdrLlyktgaiskkgekaeeerv...lDtlkeErergiTiksaaisle.....k.etkkylinliDtPGHvdFskevirgl 91 
                 ++rnigi++h+D+GKtT t+r+l++tg+i++ +e+++ ++v   +D+++ Ere+giTi+saa+ ++     + +++ky++nliDtPGH+dF+ ev+r+l
  EEA22859.1 103 KVRNIGIAAHIDSGKTTATERVLFYTGRINSIHEVRGRDSVgakMDSMDLEREKGITIQSAATFCDwvkkeDgKEEKYHFNLIDTPGHIDFTIEVERAL 201
                 79**********************************44433445************************986369************************* PP

                 HT-SEEEEEEETTTBSTHHHHHHHHHHHHTTTEEEEEEESCGSTHHHHHHHHHHHHHHHHHH..................................... CS
    GTP_EFTU  92 rvlDgavlvvdaveGvepqteevlrlalkegvpiivfiNKmDrlkaelkeiveevkqklsrk..................................... 153
                 rvlDgav++++av+Gv++qt +v r++++++vp+i f+NKmDr++a+  + ++++++kl+                                       
  EEA22859.1 202 RVLDGAVMILCAVSGVQSQTITVDRQMKRYNVPRISFVNKMDRMGANPFKAIDQINSKLRLPaaavqvpigaedefqgvvdlirmkaiynegprgeviv 300
                 ***********************************************************4449**********************************99 PP

                 ..............................................HHHHHHHHHTTT.........TTEEEEEEBTTTTBTHHHHHHHHHHHSH CS
    GTP_EFTU 154 ..............................................eeklekygekge.........kevpvvfgSalkgegvktllealvellp 193
                                                               +          +         k++pv++gSal  + ++++l+ + ++lp
  EEA22859.1 301 ekdeipehlkpvaeerrrilietladvddeiaeifldereptneqiK----------DairratialKFTPVFMGSALADKSIQPMLDGVCDYLP 385
                 99999999999999999999999999977777777776666633333..........04444446668*************************98 PP

>> EFG_II  Elongation Factor G, domain II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.3   0.0     5e-37     1e-33       1      75 []     506     580 ..     506     580 .. 0.99

  Alignments for each domain:
  == domain 1  score: 115.3 bits;  conditional E-value: 5e-37
      EFG_II   1 fPePvislaiepkskadedklskaLarlleEDptlrverdeeTketilsGmGelHleivverlkreykvevelgk 75 
                 +PePvisl+i+pk+++d+ ++ska+ar+++EDpt+rv++d e+++ti+sGmGelHl+i+ver++reykv++e+g+
  EEA22859.1 506 VPEPVISLSIKPKNNKDSANFSKAMARFQREDPTFRVSYDAESEQTIISGMGELHLDIYVERMRREYKVDCETGQ 580
                 8***********************************************************************986 PP

>> EFG_IV  Elongation factor G, domain IV
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.7   0.0   5.1e-37     1e-33       1     120 [.     581     699 ..     581     700 .. 0.99

  Alignments for each domain:
  == domain 1  score: 115.7 bits;  conditional E-value: 5.1e-37
                 TCCESCEE.SS-CCHCCCCCCCHTSSSHCCCCCEEEECCTTTTSSEEEEE--STCCCHCCCCHHHHCCCCCCTTS-TTTS--EESEEEEEEEEE--TTT CS
      EFG_IV   1 pqVayrEtirkpvkereeklkkqsggdgqyakvileiePleegsgnefvdetkggqvpkeyieavekGfqealkeGplagepvtdvkvtLldgslhevd 99 
                 pqVayrEti+++v+ +++ lkkqsgg g+ya+v+  +eP ++ ++n f+++++gg++ +++  a+ekGf+ a+++Gpl+g++v + k+++ dg++h  d
  EEA22859.1 581 PQVAYRETIGRRVE-FDHLLKKQSGGPGDYARVVGWMEPSDSLEENKFEEQIVGGAISEKFLFACEKGFNLATEKGPLIGHKVLGTKMVINDGATHMTD 678
                 8*************.************************************************************************************ PP

                 C-HHHHHHHHCHHHHHHHHCC CS
      EFG_IV 100 sseaafkpaarralkeallkA 120
                 sse+ fk+a+++a+++a++++
  EEA22859.1 679 SSEMSFKNATQQAFRKAFMES 699
                 ******************987 PP

>> EFG_C  Elongation factor G C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   77.9   0.0   2.2e-25   4.3e-22       2      88 ..     703     788 ..     702     789 .. 0.97

  Alignments for each domain:
  == domain 1  score: 77.9 bits;  conditional E-value: 2.2e-25
                 EEEEEEEEEEEEECCCCCCHHHHHHHCT-EEEEEEEE.TTEEEEEEEEEGGG-TTHHHCHHHCTTTS-EEEEEEEEEEE--HHHHHH CS
       EFG_C   2 llEPivkveievpeeyvgkvisdlssrrGeiedmeqdasgrviieaeiPlaeligfateLrslTkGegsfsmefsgYeevpgdklde 88 
                 +lEP++k  +++p e++g+vi++l++r+++i+d e    + +++ a++ l++++gf++ Lr++T+G+g+++mefs+Ye++pg++++e
  EEA22859.1 703 VLEPLMKTVVTAPIEFQGDVIGLLNKRNATINDSEIG-VDEFTVYADCSLNGMFGFSSHLRAATQGKGEYTMEFSHYEKAPGQLQKE 788
                 79*********************************99.*********************************************9987 PP

>> GTP_EFTU_D2  Elongation factor Tu domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.5   0.1   4.3e-16   8.5e-13       1      74 []     427     493 ..     427     493 .. 0.95

  Alignments for each domain:
  == domain 1  score: 48.5 bits;  conditional E-value: 4.3e-16
                  EEEEEEEEEESEEETTEEEEEECTCTTSEEEEEEEEEEEEETEEESEEETTSEEEEEEEESSCCSGSSTTCEEE CS
  GTP_EFTU_D2   1 GtvalgrvysGtlkkGdevrilgndtskkeivtrissletfhededeavaganaGvivaikgledaiivGdtlt 74 
                  G+++++rvy+Gtl+kG +v +   + +kk   +++ ++ ++h +e e+v +  aG i+a+ g+++a   Gdt+t
   EEA22859.1 427 GQLTYIRVYQGTLRKGANVFN--ARNDKK---VKVPRIVRMHSNEMEEVQEIGAGEICAVFGVDCA--SGDTFT 493
                  7899*****************..777799...*********************************7..9**985 PP

>> RF3_C  Class II release factor RF3, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.5   0.0   1.1e-09   2.2e-06      13      88 ..     513     588 ..     499     604 .. 0.82
   2 ?   -3.4   0.0         4     8e+03      57      69 ..     783     795 ..     772     798 .. 0.74

  Alignments for each domain:
  == domain 1  score: 27.5 bits;  conditional E-value: 1.1e-09
                 EEEEESSGGGHHHHHHHHHHHHHCTSSEEEEET.TSS-EEEEESSTHHHHHHHHHHHHHH---EEEEE-S--EEEE CS
       RF3_C  13 arvrlkdplkrkqlrkgleqLaeEGavqvfkeeeageelilgaVGqLQfeVveeRlknEYgvevrleslpyslarw 88 
                  +++ k+   + +++k++  ++ E  +   + ++++e++i++ +G+L +++  eR+++EY+v++++ + ++ +   
  EEA22859.1 513 LSIKPKNNKDSANFSKAMARFQREDPTFRVSYDAESEQTIISGMGELHLDIYVERMRREYKVDCETGQPQVAYRET 588
                 457889999999*************99888888899****************************998877766555 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 4
                 STHHHHHHHHHHH CS
       RF3_C  57 GqLQfeVveeRlk 69 
                 GqLQ e v++ lk
  EEA22859.1 783 GQLQKELVQKYLK 795
                 7888888877666 PP

>> ATP_bind_1  Conserved hypothetical ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   2.2e-05     0.043      74     169 ..     162     245 ..     113     265 .. 0.73

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 2.2e-05
  ATP_bind_1  74 flresldwldeelekeed.dyllfDtPGQielfthseslakiveeLes.efalvvvyLvDsqrltdptkfisgllsalsamlrlelPhvvvlnkfDll 169
                   ++ +dw+++e +kee+  + l+DtPG i +   +e      + L    + l++v  v sq++t      ++       m r+++P +  +nk+D +
  EEA22859.1 162 SAATFCDWVKKEDGKEEKyHFNLIDTPGHIDFTIEVERAL---RVLDGaVMILCAVSGVQSQTITV-----DR------QMKRYNVPRISFVNKMDRM 245
                 445666****9999997769***********988888777...55555455667776666666654.....33......4566888888888888865 PP

>> DUF442  Putative phosphatase (DUF442)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.66   1.3e+03      78      99 ..     197     219 ..     187     225 .. 0.82
   2 ?    9.6   0.0   0.00046      0.92      42      73 ..     339     370 ..     333     380 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.66
      DUF442  78 fqralaeaegpvlayCr.sGtRa 99 
                 ++ral  ++g+v++ C  sG  +
  EEA22859.1 197 VERALRVLDGAVMILCAvSGVQS 219
                 689*************6467666 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00046
      DUF442  42 gqpsnaavqeaaeaaglaylfvPvisgeited 73 
                  +p+n+ +++a+++a +a +f Pv +g+  +d
  EEA22859.1 339 REPTNEQIKDAIRRATIALKFTPVFMGSALAD 370
                 579**********************9986655 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   0.00012      0.24      43     114 .]     177     241 ..     106     241 .. 0.62

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 0.00012
                 ETTEEEEEEECGGCSSHHHHHHHHHHHHHHHHCTSEEEEEEETTTTCSHHHHHHHHHHHHHTTSEEEEEEES CS
    MMR_HSR1  43 lkgkeielvDtpGliegaseekglgkaflaleeadlillvvdaseeklkpldeeleelleeakkplilvlnk 114
                 +++ +++l+DtpG i+      ++++a++ l+ a +il  v+  +++   +d+++++++     p i  +nk
  EEA22859.1 177 EEKYHFNLIDTPGHID---FTIEVERALRVLDGAVMILCAVSGVQSQTITVDRQMKRYN----VPRISFVNK 241
                 33466********776...3336666666555577777777644555566677777774....677777766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (803 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       537  (0.0299515); expected 358.6 (0.02)
Passed bias filter:                      464  (0.0258799); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.71u 0.30s 00:00:01.01 Elapsed: 00:00:00.51
# Mc/sec: 4691.82
//
Query:       EEA22860.1  [L=116]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.3e-20   73.3   9.4      2e-20   72.7   9.4    1.3  1  Ribosomal_L36  Ribosomal protein L36


Domain annotation for each model (and alignments):
>> Ribosomal_L36  Ribosomal protein L36
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   72.7   9.4   1.1e-24     2e-20       1      38 []      78     115 ..      78     115 .. 1.00

  Alignments for each domain:
  == domain 1  score: 72.7 bits;  conditional E-value: 1.1e-24
  Ribosomal_L36   1 MKVrssvkkmcegCkvvrRkgrvyviCkknPrhKqRQG 38 
                    MK+rssvk++c+gCk vrRk+rvy+iC+knP+hKqRQG
     EEA22860.1  78 MKTRSSVKRLCDGCKPVRRKNRVYIICSKNPKHKQRQG 115
                    *************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (116 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       451  (0.0251548); expected 358.6 (0.02)
Passed bias filter:                      279  (0.0155614); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.31s 00:00:00.78 Elapsed: 00:00:00.50
# Mc/sec: 704.06
//
Query:       EEA22861.1  [L=562]
Description: threonine dehydratase, biosynthetic [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      2e-77  260.5   0.3    2.6e-77  260.2   0.3    1.1  1  PALP            Pyridoxal-phosphate dependent enzyme
    3.1e-44  148.7   0.0    8.9e-24   83.1   0.0    2.3  2  Thr_dehydrat_C  C-terminal regulatory domain of Threonine deh


Domain annotation for each model (and alignments):
>> PALP  Pyridoxal-phosphate dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  260.2   0.3   2.9e-81   2.6e-77       4     277 ..      69     343 ..      66     361 .. 0.96

  Alignments for each domain:
  == domain 1  score: 260.2 bits;  conditional E-value: 2.9e-81
                 CSSS--EEEECCTCCCCCCEEEEEEGGGSTTSBTTHHHHHHHHHHHHTTTTTSEEEEEBSSHHHHHHHHHHHHHT-EEEEEEETTS-HHHHHHHHHTT- CS
        PALP   4 gigpTPlvrlprlskelgvplflKlEslnptgSfKdRgaeyllarlkegtgaktvveassGNhgralAaaaallGlkvtivvpadaspekvallrllGa 102
                 ++ +TPl ++ +ls +l ++++lK+E+l p  SfK+Rga++ +a+l+++++ k+v+++s+GNh++++A+ a++l++++tiv+p+++++ k +   +lG 
  EEA22861.1  69 VVEETPLQHATNLSNRLECKVLLKREDLLPVFSFKLRGAYNKMAHLTQEQRWKGVIACSAGNHAQGVAYSARKLKIPATIVMPSGTPAIKHLNVSRLGG 167
                 6789*****************************************99999************************************************* PP

                 EEEEECCHHHHHHHHHHHHHHHSTTCEE--TTTSHHHHHHHHTHHHHHHHHTT.TTEEEEEEE-SSSHHHHHHHHHHHHHSTT-EEEEEEECTTCGGTT CS
        PALP 103 evvevggdydeavaaaaelaaegegaylvsqfdnptviegygtiglEileqlg.gkpdavvvpvGgGgliaGiaaglkerrpdvrvigvepegsdalar 200
                  vv+ g+d+d+a+a a++l++  ++ +++++fd+p+vi+g+gt+g+Ei++q + ++++av++++GgGgliaG++a++k   p+v++igve+  ++a+ +
  EEA22861.1 168 SVVLHGSDFDAAKAEAHRLEKV-HNLTNIPPFDDPYVIAGQGTVGMEIVRQAKlHNLEAVFCCIGGGGLIAGVGAYIKRIAPHVKIIGVETYDANAMVQ 265
                 **********************.**************************99999********************************************* PP

                 CCS..S.SS..B.SSS.CCSTCSCGTTCCHHHHSEEEEEEEEEEHHHHHHHHHHHHHHHSB-B-HHHHHHHHHH.HHH CS
        PALP 201 slragrrvtvpvsdtiadglavgspselafelldrlvdeivtvsdeealeamrllarregivvepssaaalaal.klr 277
                 sl++g+rv ++    +adg av+ ++e++f+++++ vd+i++v+++e+++a++ + ++++ ++ep++a ala+l k +
  EEA22861.1 266 SLKKGERVMLKDVGLFADGAAVKLVGEETFRICQDVVDDIIQVTTDEICAAIKDVFEDTRSILEPAGALALAGLkKYV 343
                 **************************************************************************5433 PP

>> Thr_dehydrat_C  C-terminal regulatory domain of Threonine dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.5   0.0   1.3e-21   1.2e-17       1      91 []     374     466 ..     374     466 .. 0.93
   2 !   83.1   0.0   9.9e-28   8.9e-24       2      91 .]     471     559 ..     470     559 .. 0.97

  Alignments for each domain:
  == domain 1  score: 63.5 bits;  conditional E-value: 1.3e-21
                     HHHTTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Thr_dehydrat_C   1 eraevgegleallavefpeqpGaLkkFlellggrndiTlfeYrkagekngkvLvgvevsqa...eeldelierleklgykvedlsknellkehl 91 
                     era++ge++e ll+v++pe+pGa  + ++ + ++  iT f+Yr+  e+ ++vL+g++++     +el+ + ++l+k g+k  dls++el+k+h+
      EEA22861.1 374 ERAALGEKKEVLLSVTLPEKPGAYATLIDIVTPHP-ITAFNYRFGREDIANVLMGISLPASlrtNELQRITAELKKAGMKASDLSDDELVKTHI 466
                     89********************************9.**********************96511156888999********************97 PP

  == domain 2  score: 83.1 bits;  conditional E-value: 9.9e-28
                     HHTTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  Thr_dehydrat_C   2 raevgegleallavefpeqpGaLkkFlellggrndiTlfeYrkagekngkvLvgvevsqaeeldelierleklgykvedlsknellkehl 91 
                     ++ ++ ++e++++++fpe+pGaL++Fl+ l + +++Tlf+Yr++g + g+vL+g++    e+ +el   l++lgy +e+ ++n ++k +l
      EEA22861.1 471 GGPSNVKDERVFMFQFPERPGALQRFLGHLRSTDNVTLFHYRNHGGDVGHVLAGIQCAPSEN-AELTRFLNELGYPYEECTNNAAYKMFL 559
                     6778999***************************************************9999.***********************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (562 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       404  (0.0225333); expected 358.6 (0.02)
Passed bias filter:                      399  (0.0222544); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 3903.18
//
Query:       EEA22862.1  [L=625]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.8e-08   33.3  11.2    6.9e-08   32.5  11.2    1.4  1  Zn_clus   Fungal Zn(2)-Cys(6) binuclear cluster domain


Domain annotation for each model (and alignments):
>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.5  11.2   3.8e-12   6.9e-08       1      31 [.      68      98 ..      68     105 .. 0.92

  Alignments for each domain:
  == domain 1  score: 32.5 bits;  conditional E-value: 3.8e-12
                SS-HHHHHCT---STSSSS-HHHHHCTHHHC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCt 31
                +aC+ Cr +++KCd kkP+Cs C+k++++C 
  EEA22862.1 68 RACQVCRARRTKCDNKKPSCSFCEKVGAKCI 98
                69****************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (625 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       519  (0.0289475); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.24s 00:00:00.83 Elapsed: 00:00:00.42
# Mc/sec: 4515.19
//
Query:       EEA22863.1  [L=175]
Description: mitochondrial hypoxia responsive domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.3e-25   86.8   0.1    1.2e-24   86.2   0.1    1.3  1  HIG_1_N         Hypoxia induced protein conserved region
     0.0073   16.4   1.7     0.0073   16.4   1.7    1.8  2  MAS20           MAS20 protein import receptor
  ------ inclusion threshold ------
      0.013   15.6   4.4      0.019   15.0   4.4    1.3  1  DUF2514         Protein of unknown function (DUF2514)
      0.061   12.5   3.6      0.091   11.9   3.6    1.2  1  SprA-related    SprA-related family
       0.14   11.9   0.2       0.18   11.5   0.2    1.2  1  ADP_ribosyl_GH  ADP-ribosylglycohydrolase


Domain annotation for each model (and alignments):
>> HIG_1_N  Hypoxia induced protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.2   0.1   3.4e-28   1.2e-24       1      52 []      28      79 ..      28      79 .. 0.99

  Alignments for each domain:
  == domain 1  score: 86.2 bits;  conditional E-value: 3.4e-28
     HIG_1_N  1 eeplvpiGilatvgalvrglrsmkrgdskqsnrlmraRiaaQaftvlalvaG 52
                eepl+p+G++at++al+r++rs k +ds+ +nr++raRi+aQ+ft+la+vaG
  EEA22863.1 28 EEPLIPLGCAATCYALYRAYRSGKAKDSVEMNRMFRARIYAQFFTLLAVVAG 79
                79************************************************98 PP

>> MAS20  MAS20 protein import receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.1       1.2   4.3e+03      23      32 ..      20      29 ..      15      31 .. 0.80
   2 !   16.4   1.7     2e-06    0.0073       7      81 ..      75     148 ..      70     172 .. 0.64

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 1.2
       MAS20 23 pefkkklrer 32
                ++fk++l+e+
  EEA22863.1 20 QKFKRRLKEE 29
                6899999986 PP

  == domain 2  score: 16.4 bits;  conditional E-value: 2e-06
       MAS20   7 aflgYcvYFDrkRrsdpefkkklrerrkkqakaakeeeeaekaekkk..kealeeakeelp.tdaeevekfFleevql 81 
                 a+++  +Y+   R++  ef kk++er+ ++++ a  +e +++ ++ k  k    e ++ +  t ++e e  + ++v++
  EEA22863.1  75 AVVAGGMYYKTERKQRREFEKKVEERKAQEKRDAWLRELEARDKEDKgwK----ERHAAVSvTAKKETEGAVDKNVNQ 148
                 5666679****************999999887665444444444444432....333343335556666666555554 PP

>> DUF2514  Protein of unknown function (DUF2514)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.0   4.4   5.4e-06     0.019      10     102 ..      73     168 ..      66     175 .] 0.77

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 5.4e-06
     DUF2514  10 lvaalvwG.fahGrskeeaewekrwadrdaedsqakviaeeaaReeeqrrkaaaekav.kdaqekaaaAradavgaaaaadrLrqeaakL.aaaks 102
                 l a++  G +   ++k+ +e+ek+ ++r+a++++     e +aR++e +  + +  av   a+++ + A ++ v+ a + +   ++   + +a k+
  EEA22863.1  73 LLAVVAGGmYYKTERKQRREFEKKVEERKAQEKRDAWLRELEARDKEDKGWKERHAAVsVTAKKETEGAVDKNVNQAPTEEVVEKRGTGIlDAVKA 168
                 33344457999*******************99999999999999999887777766652689999999*999999888777776666655455555 PP

>> SprA-related  SprA-related family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   3.6   2.5e-05     0.091     170     213 ..      87     131 ..      82     138 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 2.5e-05
  SprA-related 170 qekireqekqa.aekaieaqkaqveqLkkRdaEVkaHErAHAtvG 213
                    ++ re ek+  ++ka+e++ a +++L++Rd+E k   + HA+v 
    EEA22863.1  87 RKQRREFEKKVeERKAQEKRDAWLRELEARDKEDKGWKERHAAVS 131
                   3344444444314699**************************995 PP

>> ADP_ribosyl_GH  ADP-ribosylglycohydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.2     5e-05      0.18     164     234 ..      34     123 ..      28     163 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 5e-05
                     HHHHHHHHHHHHHHTT--STHHHHHH.......................HHHHTTT-HHHHHHHGGGGG---HHH.........HHHHH--SS CS
  ADP_ribosyl_GH 164 agaaayaaliaaalrgksleealdaa.....................eeelavapaeeelaaalrkalaladsdkd.vdvdaeeavdelgsgg 234
                     +g+aa+++++++a+r  + +++++                       +  +++ ++++e+++++++ +a++++d   +   + ea d+  +g+
      EEA22863.1  34 LGCAATCYALYRAYRSGKAKDSVEMNrmfrariyaqfftllavvaggMYYKTERKQRREFEKKVEERKAQEKRDAWlR---ELEARDKEDKGW 123
                     79**********************99*********************5566666667777777777777777777332...222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (175 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1391  (0.0775838); expected 358.6 (0.02)
Passed bias filter:                      561  (0.0312901); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 1218.79
//
Query:       EEA22864.1  [L=167]
Description: mitochondrial hypoxia responsive domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    7.5e-25   86.9   0.1    1.1e-24   86.4   0.1    1.3  1  HIG_1_N         Hypoxia induced protein conserved region
     0.0065   16.6   1.7     0.0065   16.6   1.7    1.8  2  MAS20           MAS20 protein import receptor
  ------ inclusion threshold ------
      0.013   15.6   4.4      0.017   15.2   4.4    1.2  1  DUF2514         Protein of unknown function (DUF2514)
      0.043   13.0   3.3      0.061   12.5   3.3    1.2  1  SprA-related    SprA-related family
       0.12   12.1   0.2       0.16   11.7   0.2    1.2  1  ADP_ribosyl_GH  ADP-ribosylglycohydrolase


Domain annotation for each model (and alignments):
>> HIG_1_N  Hypoxia induced protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.4   0.1   3.1e-28   1.1e-24       1      52 []      20      71 ..      20      71 .. 0.99

  Alignments for each domain:
  == domain 1  score: 86.4 bits;  conditional E-value: 3.1e-28
     HIG_1_N  1 eeplvpiGilatvgalvrglrsmkrgdskqsnrlmraRiaaQaftvlalvaG 52
                eepl+p+G++at++al+r++rs k +ds+ +nr++raRi+aQ+ft+la+vaG
  EEA22864.1 20 EEPLIPLGCAATCYALYRAYRSGKAKDSVEMNRMFRARIYAQFFTLLAVVAG 71
                79************************************************98 PP

>> MAS20  MAS20 protein import receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.1       1.2   4.4e+03      23      32 ..      12      21 ..       8      23 .. 0.80
   2 !   16.6   1.7   1.8e-06    0.0065       7      81 ..      67     140 ..      62     164 .. 0.64

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 1.2
       MAS20 23 pefkkklrer 32
                ++fk++l+e+
  EEA22864.1 12 QKFKRRLKEE 21
                6899999986 PP

  == domain 2  score: 16.6 bits;  conditional E-value: 1.8e-06
       MAS20   7 aflgYcvYFDrkRrsdpefkkklrerrkkqakaakeeeeaekaekkk..kealeeakeelp.tdaeevekfFleevql 81 
                 a+++  +Y+   R++  ef kk++er+ ++++ a  +e +++ ++ k  k    e ++ +  t ++e e  + ++v++
  EEA22864.1  67 AVVAGGMYYKTERKQRREFEKKVEERKAQEKRDAWLRELEARDKEDKgwK----ERHAAVSvTAKKETEGAVDKNVNQ 140
                 5666679****************999999887665444444444444432....333343335556666666555554 PP

>> DUF2514  Protein of unknown function (DUF2514)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.2   4.4   4.7e-06     0.017      10     102 ..      65     160 ..      58     167 .] 0.77

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 4.7e-06
     DUF2514  10 lvaalvwG.fahGrskeeaewekrwadrdaedsqakviaeeaaReeeqrrkaaaekav.kdaqekaaaAradavgaaaaadrLrqeaakL.aaaks 102
                 l a++  G +   ++k+ +e+ek+ ++r+a++++     e +aR++e +  + +  av   a+++ + A ++ v+ a + +   ++   + +a k+
  EEA22864.1  65 LLAVVAGGmYYKTERKQRREFEKKVEERKAQEKRDAWLRELEARDKEDKGWKERHAAVsVTAKKETEGAVDKNVNQAPTEEVVEKRGTGIlDAVKA 160
                 33344457999*******************99999999999999999887777766652689999999*999999888777776666655455555 PP

>> SprA-related  SprA-related family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   3.3   1.7e-05     0.061     170     213 ..      79     123 ..      73     130 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.7e-05
  SprA-related 170 qekireqekqa.aekaieaqkaqveqLkkRdaEVkaHErAHAtvG 213
                    ++ re ek+  ++ka+e++ a +++L++Rd+E k   + HA+v 
    EEA22864.1  79 RKQRREFEKKVeERKAQEKRDAWLRELEARDKEDKGWKERHAAVS 123
                   3344444444314699**************************995 PP

>> ADP_ribosyl_GH  ADP-ribosylglycohydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.2   4.4e-05      0.16     164     234 ..      26     115 ..      20     155 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 4.4e-05
                     HHHHHHHHHHHHHHTT--STHHHHHH.......................HHHHTTT-HHHHHHHGGGGG---HHH.........HHHHH--SS CS
  ADP_ribosyl_GH 164 agaaayaaliaaalrgksleealdaa.....................eeelavapaeeelaaalrkalaladsdkd.vdvdaeeavdelgsgg 234
                     +g+aa+++++++a+r  + +++++                       +  +++ ++++e+++++++ +a++++d   +   + ea d+  +g+
      EEA22864.1  26 LGCAATCYALYRAYRSGKAKDSVEMNrmfrariyaqfftllavvaggMYYKTERKQRREFEKKVEERKAQEKRDAWlR---ELEARDKEDKGW 115
                     79**********************99*********************5566666667777777777777777777332...222222222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (167 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1843  (0.102794); expected 358.6 (0.02)
Passed bias filter:                      779  (0.0434492); expected 358.6 (0.02)
Passed Vit filter:                        77  (0.00429472); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.46u 0.25s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 1226.11
//
Query:       EEA22865.1  [L=330]
Description: hypothetical protein PMAA_094700 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
     0.0073   15.3   0.4      0.012   14.6   0.4    1.2  1  TMEM171         Transmembrane protein family 171
  ------ inclusion threshold ------
      0.087   12.6   0.9       0.21   11.4   0.3    1.9  2  DUF4597         Domain of unknown function (DUF4597)


Domain annotation for each model (and alignments):
>> TMEM171  Transmembrane protein family 171
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.4   1.3e-06     0.012     189     310 ..     198     320 ..     190     328 .. 0.59

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 1.3e-06
     TMEM171 189 svsqdaseseegqtqstesvqvtvgdaviifPP.PPPpyfaessasa.vtkspgassllasenPPsyysifndgrtqtaeeegaaserdkesiytisgt 285
                 +v +d++ + e    + e  qv+ + +++i PP  PP+ +ae++as+ +t+ +  ++ ++ ++P + +   n++r + +++ g+ +   k ++ + s  
  EEA22865.1 198 NVLEDSKAHSE-SRSEDEIEQVVDVPSIVITPPmEPPSALAEPKASTiKTEGKRDDQKQNAKKPQPKKKGRNRTRKNSKKK-GKKKRARKAMLLSQSKN 294
                 56667755555.344566778888888888888459999*******97888899999888999988887777554443333.33222223333333333 PP

     TMEM171 286 sssseisat.qslsselpPryeekes 310
                  ++se +    +   +   r e+k+ 
  EEA22865.1 295 LTESESKVKgGKWRRKNQKRKEKKKM 320
                 33333222213444445555555554 PP

>> DUF4597  Domain of unknown function (DUF4597)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0      0.55     5e+03      35      49 ..       1      15 [.       1      20 [. 0.78
   2 ?   11.4   0.3   2.3e-05      0.21      17      39 ..     216     240 ..     204     248 .. 0.73

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 0.55
     DUF4597 35 mtlpRDsrravwlDe 49
                mt p ++++++ +D+
  EEA22865.1  1 MTSPSNTSKSILMDN 15
                778888888888886 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 2.3e-05
     DUF4597  17 dkhLdvPdiiitPPt..PtgmtlpR 39 
                 ++ +dvP i+itPP   P +++ p+
  EEA22865.1 216 EQVVDVPSIVITPPMepPSALAEPK 240
                 5678**********64355666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (330 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2332  (0.130069); expected 358.6 (0.02)
Passed bias filter:                      537  (0.0299515); expected 358.6 (0.02)
Passed Vit filter:                        78  (0.00435049); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.26s 00:00:00.81 Elapsed: 00:00:00.40
# Mc/sec: 2491.20
//
Query:       EEA22866.1  [L=293]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (293 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       461  (0.0257125); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.44u 0.27s 00:00:00.71 Elapsed: 00:00:00.42
# Mc/sec: 2075.79
//
Query:       EEA22867.1  [L=365]
Description: DUF52 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      6e-64  215.8   0.0      7e-64  215.6   0.0    1.0  1  Memo      Memo-like protein


Domain annotation for each model (and alignments):
>> Memo  Memo-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  215.6   0.0   3.9e-68     7e-64       2     271 .]      17     362 ..      16     362 .. 0.95

  Alignments for each domain:
  == domain 1  score: 215.6 bits;  conditional E-value: 3.9e-68
        Memo   2 aavAGsfYpedeeelkkqleeflekntgkkei........arviisPHagyvysgevaakayaelesskvervvilGpsHtilgskvsvlaaseleTPl 92 
                 +++AGs+Y++d+  lk+ l+  l    g+ e         ar+ii PHagy ysg+ aa ay++l+ sk +r+++lGpsH+     +++ ++  + TP 
  EEA22867.1  17 PTHAGSWYEDDTTTLKAELDGWLDAVPGEIEPfgalpipgARIIIGPHAGYAYSGPCAAWAYKALDLSKAKRIFLLGPSHHYPLATIALPEVTSYATPV 115
                 9*******************777766666544778999************************************************************* PP

        Memo  93 Gd..lkvDeelveeLvkkeeiadldetaa.laEHSlEvqlpfLkellkek........kfkivPilvsaqseetakevgealakvikdesnlviiSsDl 180
                  d  l  D e++ ++ + ++ ++++ +   + EHS+E++lp +++ l+              vPi+v++ + et+++vg  la+++ d+sn++iiSsD+
  EEA22867.1 116 SDepLPLDIEVIDKICNASSTFEIMSRRIdEREHSMELHLPYIHRKLQLTfpgrpaaeYPPLVPIMVGSTKAETERAVGALLATYLADSSNAFIISSDF 214
                 9755999**************999999999*************9999988888899954579************************************* PP

        Memo 181 sHygrrFg.................................................spqeiaesie..DrevikaleelneeelkeylektnnticGe 228
                 +H+g+rFg                                                  + ei+ si+  D   +ka+++ +++++ + l +t+nt+cG+
  EEA22867.1 215 CHWGQRFGytyyvpdapqqkpplplsfdnlpqppttvseaedaiqkvsgrslrsnkeIQTEIYDSISavDIATMKAITTGSTTQFLKILRSTGNTVCGR 313
                 *******************************************************999999*****9******************************** PP

        Memo 229 kpiavilkalkklga......kkakllkYaqssdvtsdtdsvVsyaslv 271
                 +pi vi+ al++          k+++++Y+ ssd   + +s+Vsy s+v
  EEA22867.1 314 HPIGVIMAALEAYASasgeevGKFHFIRYERSSDPDVVSESSVSYVSAV 362
                 **********999888898889***********************9975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (365 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       325  (0.0181271); expected 358.6 (0.02)
Passed bias filter:                      307  (0.0171231); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.45
# Mc/sec: 2456.32
//
Query:       EEA22868.1  [L=181]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (181 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       390  (0.0217525); expected 358.6 (0.02)
Passed bias filter:                      284  (0.0158403); expected 358.6 (0.02)
Passed Vit filter:                        13  (0.000725082); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 1280.54
//
Query:       EEA22869.1  [L=116]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.5e-08   32.2   0.0    8.8e-08   31.7   0.0    1.2  1  LSM       LSM domain
    0.00024   21.2   0.0    0.00033   20.7   0.0    1.5  1  SM-ATX    Ataxin 2 SM domain


Domain annotation for each model (and alignments):
>> LSM  LSM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.7   0.0   9.8e-12   8.8e-08       2      65 ..       9      97 ..       8      99 .. 0.96

  Alignments for each domain:
  == domain 1  score: 31.7 bits;  conditional E-value: 9.8e-12
                HHHHTTTSEEEEEETTSEEEEEEEEEEETTSEEEEEEEEEEETTET.........................EEEEEEEEEEEGGGEEEE CS
         LSM  2 flkklinkkvtvelkngrelrGtLkgfDqfmNlvLedveetlkdkk.........................ekrklglvliRGnnivli 65
                 l++l+++++++ +++ r ++G++k+ D   N++L ++ e++  ++                         ++r++glv++ G  i+ i
  EEA22869.1  9 YLQSLLGRNLRIHTTDTRMFVGIFKCTDMDQNIILANTFEYRLPSQsavqaaaaettstsadgagkfkmdmTSRFIGLVVVPGQYITKI 97
                799***************************************99999************************************999866 PP

>> SM-ATX  Ataxin 2 SM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.7   0.0   3.6e-08   0.00033       7      51 ..       9      51 ..       3      99 .. 0.85

  Alignments for each domain:
  == domain 1  score: 20.7 bits;  conditional E-value: 3.6e-08
                HHHTTTTSEEEEEETTS-EEEEEEEEE-T..T--EEEEEEEETTS CS
      SM-ATX  7 lltslvGkevevtvknGevyeGifstvslekdfsvvLkmarkvkk 51
                 l sl G++ ++++++   + Gif+++++  d +++L ++ + + 
  EEA22869.1  9 YLQSLLGRNLRIHTTDTRMFVGIFKCTDM--DQNIILANTFEYRL 51
                5789*************************..99999988765554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (116 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       371  (0.0206927); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.35u 0.27s 00:00:00.62 Elapsed: 00:00:00.40
# Mc/sec: 878.62
//
Query:       EEA22870.1  [L=513]
Description: serine/threonine protein phosphatase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.5e-37  130.1   0.1    2.3e-37  129.5   0.1    1.3  1  Metallophos  Calcineurin-like phosphoesterase
    3.3e-16   59.5   0.1    6.2e-16   58.6   0.1    1.5  1  STPPase_N    Serine-threonine protein phosphatase N-terminal 
  ------ inclusion threshold ------
        0.3   10.2   7.0       0.39    9.9   7.0    1.1  1  SOG2         RAM signalling pathway protein


Domain annotation for each model (and alignments):
>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  129.5   0.1   3.8e-41   2.3e-37       2     201 ..     240     431 ..     239     434 .. 0.92

  Alignments for each domain:
  == domain 1  score: 129.5 bits;  conditional E-value: 3.8e-41
                  EEEEEESBTBTTCCTHHHHHHHHHHHH..HHHTTESEEEEESTSSSSSHHHHHHHHH.HHHHHHHTSEEEEEC-TTS........CHHHHHHHHHHHH CS
  Metallophos   2 rilvigDlHlalgggqlddllkllddl..lreekpdlvllaGDlvdrgdlekellel.laalvkypipvylllGNHe........gfeeellnkygyl 88 
                  ++ ++gD+H     gq+ dl++l++ +  ++   ++l+l  GD+vdrg  + e++ l l++++kyp +++ll+GNHe        gf++e++++    
   EEA22870.1 240 PVKIVGDVH-----GQYTDLIRLFEMCgfPP-AANYLFL--GDYVDRGKQSLETILLlLCYKLKYPENFFLLRGNHEcanvtrvyGFYDECKRRCN-- 327
                  5789*****.....***********997444.4789999..*******6666666666************************************77.. PP

                  HHHHHHHEHHHCEEETSEEEEEETTEEEEEEEESE.CEEETHHHHHHHHHHHSCHHHHCC...HHHHHHHHHHTTCSEEEEEESSESSCSSSCSCCHH CS
  Metallophos  89 gifsepwrsdaevfnnlplaslgsgslkvlllhGg.spellvsldklgslnleleapepg...dewlkdlekrekadwvivlgHsplyrgsgylfgde 182
                      ++w++++++fn+lp+a+++ g  k++++hGg sp l  + d+++++ +++++p+ g   d++++d       + ++   + p++rg +y fg +
   EEA22870.1 328 ---IKIWKTFVDTFNCLPIAAIVAG--KIFCVHGGlSPSL-SHMDDIRGIARPTDVPDYGllnDLLWSD-------PADMEEDWEPNERGVSYCFGKK 412
                  ...99********************..********65555.******************9*********.......********************** PP

                  HHHHHHHHTTESEEEEESS CS
  Metallophos 183 aledllkkygvdlvisGHt 201
                  +++d+l++++ dlv+++H 
   EEA22870.1 413 VIMDFLQRHDFDLVCRAHM 431
                  ******************7 PP

>> STPPase_N  Serine-threonine protein phosphatase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.6   0.1     1e-19   6.2e-16       1      48 []     190     238 ..     190     238 .. 0.92

  Alignments for each domain:
  == domain 1  score: 58.6 bits;  conditional E-value: 1e-19
   STPPase_N   1 vDdiIerLlevrg.kpggkkvqLseaEIrqlCakareiFLsQPtLLeLe 48 
                 +Dd+I+rLl++++ ++  k v+L++aEI ++C++are++LsQP LLeL+
  EEA22870.1 190 LDDMISRLLDAGYsTKITKAVCLKNAEIIAICTAARELLLSQPALLELS 238
                 7************766667888**************************6 PP

>> SOG2  RAM signalling pathway protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   7.0   6.5e-05      0.39     215     339 ..      19     166 ..       3     225 .. 0.60

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 6.5e-05
        SOG2 215 agsfsaqdveqGaalt..plrsdqipfnlsrsrrssssgnsaspaangaqsetsersasssg.vqssasstPlgegstsppgalsrqslsttgststlt 310
                  +sfs+ d +++  +   ++rs+ +        + ++ +n+ sp +++a     +rs ++s+ ++ss  ++P+ ++st +    + +++s+tg  +++ 
  EEA22870.1  19 YPSFSRTDTKESIRSLkgSIRSKIPG-------SRGNDKNNDSPRNSTAGFG-EDRSDEASVrSTSSLKQQPVAQQSTVS----NDPIPSRTGTPEPPP 105
                 45566555555544443333333222.......2333334444444444333.455555666677777888888888876....777888888888888 PP

        SOG2 311 sssksrs............ssrsnt..nasastprslattpa....................p 339
                 s s+s+s            +  s +  ++s+ +p+  + tp+                     
  EEA22870.1 106 SPSQSTSlnrghkdvdaaqQ--SGEvdLVSDAPPSVPPVTPQapgesilvrpenqinpiildI 166
                 88888888888888777431..33345888888888888888444444444444444444441 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (513 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       519  (0.0289475); expected 358.6 (0.02)
Passed bias filter:                      378  (0.0210832); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.27s 00:00:00.80 Elapsed: 00:00:00.43
# Mc/sec: 3587.86
//
Query:       EEA22871.1  [L=968]
Description: small nucleolar ribonucleoprotein complex subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.3e-12   46.3   5.1       0.15   13.0   0.0    8.7 10  WD40         WD domain, G-beta repeat
    7.7e-08   32.5   0.0      0.021   15.1   0.0    5.9  7  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
     0.0031   17.1   0.6      0.031   13.8   0.6    2.5  1  PQQ_2        PQQ-like domain
  ------ inclusion threshold ------
      0.069   13.3   0.0        0.3   11.2   0.0    2.1  2  Milton       Kinesin associated protein


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0      0.26   1.2e+03      25      38 .]      39      52 ..      10      52 .. 0.69
   2 ?    3.2   0.0     0.042   1.9e+02       6      36 ..     121     168 ..     116     168 .. 0.62
   3 ?    5.1   0.0     0.011        47      21      38 .]     199     216 ..     179     216 .. 0.73
   4 !   11.5   0.1    0.0001      0.45      11      38 .]     237     265 ..     220     265 .. 0.78
   5 !   13.0   0.0   3.3e-05      0.15       4      33 ..     272     302 ..     269     307 .. 0.85
   6 ?   -1.5   0.0       1.3   5.7e+03      13      37 ..     378     401 ..     365     402 .. 0.56
   7 ?   -0.8   0.0      0.77   3.5e+03      12      26 ..     429     443 ..     421     454 .. 0.72
   8 ?   -4.0   0.0         4   1.8e+04      16      25 ..     486     495 ..     484     496 .. 0.79
   9 ?    2.7   0.0     0.059   2.7e+02      13      29 ..     554     570 ..     537     577 .. 0.77
  10 ?    0.6   0.1      0.27   1.2e+03      13      35 ..     933     946 ..     920     947 .. 0.77

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.26
                EEEEETTSEEEEEE CS
        WD40 25 lasGsdDgtvriWd 38
                la G  +g + iW+
  EEA22871.1 39 LAVGRANGDIEIWN 52
                677877*******8 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.042
                 EEESS.SSEEEEE....EETTSSE............EEEEETTSEEEE CS
        WD40   6 tltGH.ssvtsla....fspdgaw............lasGsdDgtvri 36 
                 + +G  + +++l     + p++              la G+ Dg++ i
  EEA22871.1 121 HSSGSyGEIWCLTaqprWAPSSEKgapaegeytgqhLAIGCADGSIVI 168
                 445554558888888884444444444444445555999999***976 PP

  == domain 3  score: 5.1 bits;  conditional E-value: 0.011
                 TSSEEEEEETTSEEEEEE CS
        WD40  21 dgawlasGsdDgtvriWd 38 
                 + + la+G  D ++r++d
  EEA22871.1 199 NRHVLAAGYADSSIRLFD 216
                 4444899989******98 PP

  == domain 4  score: 11.5 bits;  conditional E-value: 0.0001
                 SS..EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  11 ss..vtslafspdgawlasGsdDgtvriWd 38 
                 ++  v+s++  pdg+++ sG+  g +r+Wd
  EEA22871.1 237 KDilVWSVKSLPDGTLV-SGDSTGEIRFWD 265
                 45778***********7.8*66*******9 PP

  == domain 5  score: 13.0 bits;  conditional E-value: 3.3e-05
                 EEEEESS.SSEEEEEEETTSSEEEEEETTSE CS
        WD40   4 lrtltGH.ssvtslafspdgawlasGsdDgt 33 
                 ++ ++GH  +v ++a+s dg  ++sG+ D+ 
  EEA22871.1 272 VQRIRGHqADVLDVAVSIDGETVVSGGADRR 302
                 56679**888****************99986 PP

  == domain 6  score: -1.5 bits;  conditional E-value: 1.3
                 EEEEEEETTSSEEEEEETTSEEEEE CS
        WD40  13 vtslafspdgawlasGsdDgtvriW 37 
                 ++ la  +++++++ + + + vri+
  EEA22871.1 378 ICQLASGSSSRFMM-SFWEREVRIY 401
                 74444444555544.3567777776 PP

  == domain 7  score: -0.8 bits;  conditional E-value: 0.77
                 SEEEEEEETTSSEEE CS
        WD40  12 svtslafspdgawla 26 
                 ++ts a s dg++l+
  EEA22871.1 429 NITSAALSTDGSLLV 443
                 399999999999986 PP

  == domain 8  score: -4.0 bits;  conditional E-value: 4
                 EEEETTSSEE CS
        WD40  16 lafspdgawl 25 
                 ++ spd +wl
  EEA22871.1 486 VSLSPDLRWL 495
                 6679**9**8 PP

  == domain 9  score: 2.7 bits;  conditional E-value: 0.059
                 EEEEEEETTSSEEEEEE CS
        WD40  13 vtslafspdgawlasGs 29 
                 ++ + fs+d++++a+G+
  EEA22871.1 554 IRTITFSSDSKLFATGD 570
                 9999*********9985 PP

  == domain 10  score: 0.6 bits;  conditional E-value: 0.27
                 EEEEEEETTSSEEEEEETTSEEE CS
        WD40  13 vtslafspdgawlasGsdDgtvr 35 
                 + +l        ++++s+D++v 
  EEA22871.1 933 I-DL--------VSTSSRDKSVE 946
                 5.55........9999*****96 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0      0.26   1.2e+03      53      76 ..      39      62 ..      34      81 .. 0.57
   2 ?   -3.5   0.0         3   1.3e+04      59      87 ..     105     132 ..      95     133 .. 0.64
   3 !    7.5   0.0    0.0011       5.1      49      76 ..     153     180 ..     151     199 .. 0.72
   4 !   15.1   0.0   4.6e-06     0.021      38      81 ..     189     231 ..     182     247 .. 0.81
   5 ?    0.7   0.0      0.15   6.7e+02      48      82 ..     248     281 ..     234     294 .. 0.81
   6 ?   -1.3   0.0      0.63   2.8e+03      38      66 ..     427     454 ..     423     461 .. 0.77
   7 ?   -1.0   0.0      0.48   2.2e+03      33      57 ..     546     570 ..     487     581 .. 0.67

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.26
  ANAPC4_WD40 53 Lavaysdgevrlldaesgkvvhsl 76
                 Lav+ ++g +++ +   g   ++ 
   EEA22871.1 39 LAVGRANGDIEIWNPLRGAWFQET 62
                 777777777777766555554444 PP

  == domain 2  score: -3.5 bits;  conditional E-value: 3
  ANAPC4_WD40  59 dgevrlldaesgkvvhslsvksekavtcl 87 
                   ++v   d e+gk  +++s +  + + cl
   EEA22871.1 105 TNTVTEWDLEKGKPARHSSGSYGE-IWCL 132
                  356667788888888777766664.7776 PP

  == domain 3  score: 7.5 bits;  conditional E-value: 0.0011
  ANAPC4_WD40  49 dgklLavaysdgevrlldaesgkvvhsl 76 
                   g+ La++++dg++ +l+  + ++    
   EEA22871.1 153 TGQHLAIGCADGSIVILSTADDDLRFVR 180
                  6999**************9988765433 PP

  == domain 4  score: 15.1 bits;  conditional E-value: 4.6e-06
  ANAPC4_WD40  38 dsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvkse 81 
                  + +v s+ ++ + ++La +y+d+++rl+d+ +g++++++s ++ 
   EEA22871.1 189 NVRVLSITFQ-NRHVLAAGYADSSIRLFDIRNGRLLRTVSLGRG 231
                  4455566665.569***********************9998775 PP

  == domain 5  score: 0.7 bits;  conditional E-value: 0.15
  ANAPC4_WD40  48 pdgklLavaysdgevrlldaesgkvvhslsvksek 82 
                  pdg  L+ + s ge+r+ d ++  +v+ ++ ++ +
   EEA22871.1 248 PDG-TLVSGDSTGEIRFWDPKNYSLVQRIRGHQAD 281
                  455.5899***************999999888764 PP

  == domain 6  score: -1.3 bits;  conditional E-value: 0.63
  ANAPC4_WD40  38 dsevrsLaWkpdgklLavaysdgevrlld 66 
                  d++++s a + dg+lL+ ++  +++r+++
   EEA22871.1 427 DENITSAALSTDGSLLVLSTT-TTIRMFS 454
                  78899999999**99988765.5566665 PP

  == domain 7  score: -1.0 bits;  conditional E-value: 0.48
  ANAPC4_WD40  33 eedkedsevrsLaWkpdgklLavay 57 
                  +  + ++++r + ++ d kl+a + 
   EEA22871.1 546 TLGDYERTIRTITFSSDSKLFATGD 570
                  4455667888888888888888775 PP

>> PQQ_2  PQQ-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.8   0.6     7e-06     0.031      16     177 ..     129     305 ..      73     351 .. 0.67

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 7e-06
       PQQ_2  16 lWrvdlar......plgggvsravlsggtlfvatgggrlvaldaatGkvlWettlegpvvga.....plvaegrvvvva.sdgqlialdaedGkrlWst 102
                 +W ++ ++      ++g+  ++ +  g++l+++   g +v l++a+  +++ ++l++ v ++      ++ + +v+++  +d +++ +d+++G++l ++
  EEA22871.1 129 IWCLTAQPrwapssEKGAPAEGEY-TGQHLAIGCADGSIVILSTADDDLRFVRRLNASVTKNvrvlsITFQNRHVLAAGyADSSIRLFDIRNGRLLRTV 226
                 555543333332323555565566.99999999999999999999999999999988877777777756666666555458999999999999997776 PP

       PQQ_2 103 qqrseepae...lrssaspavagdtvvvgessgklvaldpkdGkvlWerelaaprgtselsrvgdisgrpvvaeg....tVy 177
                  + +++      +++ + +++ ++t+v g+s g++   dpk+ +++      ++++++ l+  ++i+g++vv++g    tV+
  EEA22871.1 227 SLGRGPIGGpkdILVWSVKSLPDGTLVSGDSTGEIRFWDPKNYSLVQRI---RGHQADVLDVAVSIDGETVVSGGadrrTVL 305
                 6666222222223333333333777777777777777777766664443...445555555555555555555443333333 PP

>> Milton  Kinesin associated protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   6.7e-05       0.3      27     148 ..     243     366 ..     239     382 .. 0.70
   2 ?   -2.6   0.1       1.2   5.2e+03      84     108 ..     803     825 ..     731     841 .. 0.58

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 6.7e-05
      Milton  27 SssstPrssvyggd..gssvsldnrtssilsetsssedsgeeepkk.aGvPGapGakdLeaALrrLslrrenylserrffevereRkllala.agtysy 121
                 S  s P +++  gd  g+    d +++s +     ++ +  +      G    +G+ d ++ L rL + ++n  s rr++ev ++R  +++  ++   y
  EEA22871.1 243 SVKSLPDGTLVSGDstGEIRFWDPKNYSLVQRIRGHQADVLDVAVSiDGETVVSGGADRRTVLYRLKPGKKNDKS-RRWMEVMHRRY-HTHDvKKFAVY 339
                 56677777777777533344567777777666555554444444444788889****************888877.8899**99998.55553777778 PP

      Milton 122 deeekggssalTPsdSimSlgssslgs 148
                 + ++ + + +  P  S++ l   ++g+
  EEA22871.1 340 ESKDMSIAVSGGPDASLVVLPLRESGK 366
                 877777766678888887776666544 PP

  == domain 2  score: -2.6 bits;  conditional E-value: 1.2
      Milton  84 aALrrLslrrenylserrffevere 108
                 + +r+++  r+n  s  ++ +ve++
  EEA22871.1 803 TKMRKITGNRQN--SKGQWIDVEKH 825
                 334444444444..34445555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (968 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       531  (0.0296168); expected 358.6 (0.02)
Passed bias filter:                      401  (0.022366); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.78u 0.31s 00:00:01.09 Elapsed: 00:00:00.49
# Mc/sec: 5886.74
//
Query:       EEA22872.1  [L=412]
Description: G1/S-specific cyclin Cln1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-36  123.5   0.4    2.1e-35  121.2   0.1    2.0  2  Cyclin_N  Cyclin, N-terminal domain
    5.7e-12   45.8   0.8    1.8e-11   44.2   0.2    2.1  2  Cyclin_C  Cyclin, C-terminal domain


Domain annotation for each model (and alignments):
>> Cyclin_N  Cyclin, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.2   0.1   2.3e-39   2.1e-35       2     126 ..      58     184 ..      57     185 .. 0.96
   2 ?   -0.2   0.0     0.084   7.5e+02      41     100 ..     196     255 ..     189     265 .. 0.79

  Alignments for each domain:
  == domain 1  score: 121.2 bits;  conditional E-value: 2.3e-39
                 HHHHHHHHHCHTS-STTCTTCTSSS-HHHHHHHHHHHHHHHHHTT--TTHHHHHHHHHHHHHHHS---CCCHHHHHHHHHHHHHHH..HSSS---HHHH CS
    Cyclin_N   2 ilknlieqelkflpkpdyldqqpelnpemRailidwlvevaekfkltpetlflavnyldRflskksvpkdklqlvgatcLllAaKv..eeisppkledl 98 
                  l+++   ++++lp+ + +d q+e+++ mR+ l+d+l+e ++ f+l+p+tlfla+n+ldR++sk+ v k++ qlvg+++Ll+AaK+  ++ ++p++++l
  EEA22872.1  58 CLQHMLDMDTATLPDVESIDIQTEIQWFMRPYLLDFLIEAHAAFQLQPSTLFLAINLLDRYCSKRVVYKRHYQLVGCSALLIAAKYgdKKEHVPTIREL 156
                 67899999999***************************************************************************765555******* PP

                 HHHTTTSS-HHHHHHHHHHHHHHTTT-- CS
    Cyclin_N  99 vyitdeafteeeilemErliLetLnfdl 126
                   ++ + ++ +++l+mE ++L+tL + +
  EEA22872.1 157 KSMCCSLYDDDMFLQMEWHVLQTLGWTI 184
                 **************************97 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.084
                 HHHHTT--TTHHHHHHHHHHHHHHHS---CCCHHHHHHHHHHHHHHHHSSS---HHHHHH CS
    Cyclin_N  41 vaekfkltpetlflavnyldRflskksvpkdklqlvgatcLllAaKveeisppkledlvy 100
                   + ++ +pe+ +la+ +l+  l ++++  +    ++ ++L lA  + + + p++ +++ 
  EEA22872.1 196 ALVDMQYDPEVEHLALYILEISLFHREFVSKPSADLAKAALALARCILNRRQPEATEWAA 255
                 556677788999999999998888888888888888999999998888888888887765 PP

>> Cyclin_C  Cyclin, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0      0.39   3.5e+03      74      89 ..      50      65 ..      44      76 .. 0.80
   2 !   44.2   0.2     2e-15   1.8e-11       1     117 [.     187     292 ..     187     294 .. 0.88

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 0.39
                --HHHHHHHHHHHHHH CS
    Cyclin_C 74 yskedlkpcvelilel 89
                + +e l +c +++l++
  EEA22872.1 50 AREEYLDDCLQHMLDM 65
                5788899999999986 PP

  == domain 2  score: 44.2 bits;  conditional E-value: 2e-15
                 --HHHHHHHHHCCSSHT.-HCCHHCHHCHHHHHHCSCCHCCS-HHHHHHHHHHHCCHHHHS--S-HHHHHHC.---HHHHHHHHHHHHHHHHHHHGSS- CS
    Cyclin_C   1 ptplsFlrrflkaadasedselrtlakylleltlldydflsyppSliAaaalllarstlnspewtetlehyt.gyskedlkpcvelilellssapsskl 98 
                 pt+ sFl+  l   ++  d+e+++la y+le++l + +f+s p   +A aal+lar++ln+ +  ++ +++   y+ + l  + +++++ +        
  EEA22872.1 187 PTVDSFLNIALVDMQY--DPEVEHLALYILEISLFHREFVSKPSADLAKAALALARCILNRRQ--PEATEWAaTYDPNTLVGLSQQLHSPS-------- 273
                 8999*****9555566..78***************************************7777..444444448***********999988........ PP

                 -HHCCCCTCGGGCCCGGS- CS
    Cyclin_C  99 qavrrkyssskfhkvstls 117
                 q  +rkyss  + ++s+l 
  EEA22872.1 274 QVLYRKYSSAHYSRISKLL 292
                 799************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (412 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       530  (0.029561); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.25s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 2798.69
//
Query:       EEA22873.1  [L=351]
Description: lipase/esterase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.1e-43  149.6   0.0    1.4e-43  149.2   0.0    1.2  1  Abhydrolase_3  alpha/beta hydrolase fold
    2.1e-06   28.5   0.6    3.3e-06   27.9   0.6    1.3  1  Abhydrolase_6  Alpha/beta hydrolase family
    1.2e-05   24.4   0.0    2.2e-05   23.5   0.0    1.3  1  COesterase     Carboxylesterase family
  ------ inclusion threshold ------
       0.19   10.4   0.8        1.1    7.9   0.0    2.0  2  AXE1           Acetyl xylan esterase (AXE1)
        0.4   10.1   3.1        5.2    6.5   2.3    2.5  2  Esterase_phd   Esterase PHB depolymerase


Domain annotation for each model (and alignments):
>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  149.2   0.0     4e-47   1.4e-43       1     210 [.      93     323 ..      93     324 .. 0.84

  Alignments for each domain:
  == domain 1  score: 149.2 bits;  conditional E-value: 4e-47
                    EEEE--STTTS--TTTTHHHHHHHHHHHTSEEEEEE---TTTS-TTHHHHHHHHHHHHHHHTH......HHHTET.TCEEEEEEETHHHHHHHHHH CS
  Abhydrolase_3   1 lvyfHGGGfvlgsldthdalcrelakelgavvvsvdYrlAPehpfPaavedalaalrwlaeqa......welgad.psrivlaGdSaGGnlaaava 89 
                    +vy+HGGG+++gs++   + cr+l++ lg+v+v++ Yr  Pe pfPa ++da++ l+w+a++a      + +++   +  v++G SaGG +aa +a
     EEA22873.1  93 VVYYHGGGWTIGSPEDTAPACRNLVQTLGVVCVAPSYRQGPEDPFPAGINDAWDGLKWMAAHAvselanAGASVSlSAGFVVGGSSAGGSMAAILA 188
                    79*************************************************************888754222233355899*************** PP

                    HHHHHTT---...EEEEEEESE..............-SSTSSTTSHHHHHCHHTTTSSSSCHHHHHHHHHHHSSGGGGGSTTTSGGGCS.-SST-- CS
  Abhydrolase_3  90 lrardegepk...vagqvliyP..............vtdlertesesikkaeeladgplltraaldlfwrlylpeadrddplaspllae.dlsglp 167
                    + arde+ +    ++g++l++P              +   + ++s   +++ + +++p+l+++  ++f +  +   d+++p++ p   +   +glp
     EEA22873.1 189 HLARDEKASLaapITGYFLLSPmilppetfkkfpanW---KYKDSYLSRDQDACKQDPILSPQLEKIFHDSAA--GDFESPMFVPFIWPtGHAGLP 279
                    *****97444799*********888877754443222...222333333444558889998888888888887..69999****99886369**** PP

                    -EEEEEETT-TTHHHHHHHHHHHH.HTT--EEEEEETTEETTGG CS
  Abhydrolase_3 168 ptlvvvaefDplrdegeayaerlr.aagvevelieyegmvHgfa 210
                    +t+ +v++ D+ rde+  y + lr ++ ve++l  y+gm+H f+
     EEA22873.1 280 RTYFQVCGMDIVRDEDLIYEQLLReENRVETRLDIYPGMPHTFW 323
                    ************************5599**************97 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.9   0.6   9.2e-10   3.3e-06       5     207 ..      97     320 ..      92     334 .. 0.53

  Alignments for each domain:
  == domain 1  score: 27.9 bits;  conditional E-value: 9.2e-10
                    --GC.....G............CHHHHHHHHCCTCEEEEE--TTSTS-GGCS--HHH....CHHH..HHHHCCTT........TTSEEEEEETCHH CS
  Abhydrolase_6   5 HGagssassW............lvapLaallaagvhvlapDlpGhGrsdpppldled....ladl..aalldelaa......gggpvvlvGHSlGG 76 
                    HG+g     W            +  +L+  l  gv ++ap+++ +G+ dp p + +d    l  +  a+++ ela+          +v+ G S GG
     EEA22873.1  97 HGGG-----WtigspedtapacR--NLVQTL--GVVCVAPSYR-QGPEDPFPAGINDawdgLK-WmaAHAVSELANagasvsLSAGFVVGGSSAGG 181
                    8888.....85554433322111..333333..355599***5.9*88888877777433222.13555555555555557777777********* PP

                    HHHHHHHHCC..EE.EEES-..----TTTS----TTHHHHHHTT-C....CCCHCCHS-HSCCCCHHH...CCCCHCHCCCGHHHHCCHHC..... CS
  Abhydrolase_6  77 alalaaaplalvvg.vlldppptalpagllaaalelllallallrl....lawlsreplprlfladed...adaawrarlarlaallaglg..... 159
                    ++a+ +a+la++++  l +p   +++  ll++ + +++++ +  +     + +ls   ++++ +++++   ++ +    ++++ ++ ++++     
     EEA22873.1 182 SMAAILAHLARDEKaSLAAP---ITGYFLLSPMILPPETFKKFPANwkykDSYLS---RDQDACKQDPilsPQLEKIFHDSAAGDFESPMFvpfiw 271
                    **********8888455555...44444444444444444443333222345554...33344444443333455555555555555544431111 PP

                    HTTCCHHTT-TTGC...EEECTT-CHHHHCHHCCCHSTTEEETCE...SSS CS
  Abhydrolase_6 160 llpaaawadlpvpl...lvlggeDplvprllerllaqagarlpvvlpgaGH 207
                    +  +a ++++  ++    ++ +eD ++ +ll++  +    rl +++pg  H
     EEA22873.1 272 PTGHAGLPRTYFQVcgmDIVRDEDLIYEQLLREENR-VETRL-DIYPGMPH 320
                    111223333333334331223666677777777777.77777.77777777 PP

>> COesterase  Carboxylesterase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   0.0   6.2e-09   2.2e-05      92     146 ..      79     133 ..      62     134 .. 0.85

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 6.2e-09
                 EEEESSSSSTTSSEEEEEEE--STTTS-BGCG..S-THHHHHHHTSEEEEE----HH CS
  COesterase  92 vytPkekkeakkklPVlVwihGggfqtgsase..ydgsaLaaegnvivVtinYRlGv 146
                 v+ P ++  ++   P +V+ hGgg ++gs ++    +++L+++ +v+ V+ +YR G+
  EEA22873.1  79 VFRPVDQ--KEAPSPLVVYYHGGGWTIGSPEDtaPACRNLVQTLGVVCVAPSYRQGP 133
                 7888754..45555****************99767789****************996 PP

>> AXE1  Acetyl xylan esterase (AXE1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   0.0    0.0003       1.1      54      95 ..      60     102 ..      40     111 .. 0.78
   2 ?    0.4   0.4     0.056     2e+02     177     203 ..     173     199 ..     158     206 .. 0.87

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0003
                 EEEEEEEEEEGGGEEEEEEEEEES..SSSSEEEEEEEE-TT-- CS
        AXE1  54 vkvydltfegvrgarikaklvlPke.keeklPavvefhGYegs 95 
                 v  +d+ + +  g++++a + +P + ke + P+vv +hG   +
  EEA22873.1  60 VIEHDIFYPARDGHQLRACVFRPVDqKEAPSPLVVYYHGGGWT 102
                 455899*****************75156689*******96655 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.056
                 EEEEETHHHHHHHHHHHH-SS-SEEEE CS
        AXE1 177 avlGasqGGalalavaalekrikavva 203
                 +v G+s GG++a   a l ++ ka +a
  EEA22873.1 173 VVGGSSAGGSMAAILAHLARDEKASLA 199
                 5778999**********9999888765 PP

>> Esterase_phd  Esterase PHB depolymerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   2.3    0.0015       5.2      96     126 ..     169     199 ..      77     204 .. 0.62
   2 ?    1.4   0.0     0.051   1.8e+02       4      37 ..     311     344 ..     308     349 .. 0.90

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0015
  Esterase_phd  96 aarvyvaGlsaGaaladllalhypdvfaava 126
                   +a   v G saG+++a +la+   d  a++a
    EEA22873.1 169 SAGFVVGGSSAGGSMAAILAHLARDEKASLA 199
                   344568899************9999887765 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.051
  Esterase_phd   4 rlylppGarrgamplvvmlhGctqsveefaaGtr 37 
                   rl + pG +     +  ml   ++   +fa+G r
    EEA22873.1 311 RLDIYPGMPHTFWNMFGMLTQGKKAKRDFAEGMR 344
                   78889*****99********************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (351 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       303  (0.0169); expected 358.6 (0.02)
Passed bias filter:                      281  (0.0156729); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.45u 0.24s 00:00:00.69 Elapsed: 00:00:00.39
# Mc/sec: 2699.57
//
Query:       EEA22874.1  [L=362]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.7e-10   39.6   0.0    2.5e-05   24.2   0.0    2.2  2  Glyco_transf_34  galactosyl transferase GMA12/MNN10 family
  ------ inclusion threshold ------
       0.29   11.1   2.0        7.8    6.4   0.1    2.2  2  DUF1045          Protein of unknown function (DUF1045)


Domain annotation for each model (and alignments):
>> Glyco_transf_34  galactosyl transferase GMA12/MNN10 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.4   0.3   5.3e-06     0.048      25      95 ..      67     138 ..      58     150 .. 0.69
   2 !   24.2   0.0   2.7e-09   2.5e-05     132     231 ..     149     253 ..     145     258 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 5.3e-06
  Glyco_transf_34  25 lllkvikNrvdYaekhgyeifykkvsallaeemnsvWaklpairaamkkyP..eaewiWwlDqdAlimnmdls 95 
                      l +++++     a++ gy +++   +++ +  +n+    l ++ + ++k P    ew+ w+D+d +i+n+++ 
       EEA22874.1  67 LYERALQSHERHAQRWGYPMYV-LEEDISEGFWNKPSYVLSLVIQELAKPPakRCEWLMWVDADSIIINPAIP 138
                      5566777777788888998887.334444434444444456667788888844479*************9876 PP

  == domain 2  score: 24.2 bits;  conditional E-value: 2.7e-09
  Glyco_transf_34 132 edvlviisqdwnglnagsflirnsewsk.lllDlwadpllrekkkavtesdeqsaleyllekh......pevlskvglveqkvinsydegekel 218
                      ++++++ s+d ngln+g  ++    w+   l++++  pl+  +      s++q+a++ +++k       +  ++ +++++   in y+   +++
       EEA22874.1 149 SEIHFVASKDQNGLNTGIVFFHVHPWTVsMLVETLGYPLYLPEIDL-GRSADQEAMARIMKKTtggpkgEGYAEGMVYLPRPWINTYEWH-HAY 240
                      6899**********************961577******99988777.899**********97522222256889999999*******988.89* PP

  Glyco_transf_34 219 gykegdlvvhfag 231
                      + ++g+++vhf g
       EEA22874.1 241 EGEKGNMLVHFPG 253
                      ***********88 PP

>> DUF1045  Protein of unknown function (DUF1045)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.4   0.1   0.00087       7.8      89     106 ..      73      91 ..      66      91 .. 0.83
   2 ?    4.1   0.2    0.0047        42      38      95 ..     303     358 ..     271     360 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.4 bits;  conditional E-value: 0.00087
     DUF1045  89 arqealLerWGyP.yVlde 106
                 +++e++ +rWGyP yVl+e
  EEA22874.1  73 QSHERHAQRWGYPmYVLEE 91 
                 4678899******999996 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.0047
     DUF1045  38 varlggflALvpaapsealqalAaacvraldefraplseaelarrraerLsarqealL 95 
                  +++++ + L p++ s++l++ A + vr+  ++r+ ++e el +++ ++L+a+ ++ L
  EEA22874.1 303 ANSVQEDIMLSPTGTSTSLRQAAVNNVRT--ALREHADEPELVQQQVDELKAAVREEL 358
                 56677778899**********99999996..79*****************99988877 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (362 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       513  (0.0286129); expected 358.6 (0.02)
Passed bias filter:                      429  (0.0239277); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.30s 00:00:00.84 Elapsed: 00:00:00.48
# Mc/sec: 2282.98
//
Query:       EEA22875.1  [L=314]
Description: acetamidase/formamidase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.8e-55  188.3   0.0    2.8e-31  108.7   0.0    2.0  2  FmdA_AmdA  Acetamidase/Formamidase family


Domain annotation for each model (and alignments):
>> FmdA_AmdA  Acetamidase/Formamidase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.3   0.0   2.7e-26   4.8e-22      11     156 ..       8     147 ..       1     150 [. 0.94
   2 !  108.7   0.0   1.6e-35   2.8e-31     201     371 ..     151     313 ..     146     314 .] 0.88

  Alignments for each domain:
  == domain 1  score: 78.3 bits;  conditional E-value: 2.7e-26
   FmdA_AmdA  11 qeeklhNRwHpdipavaevkpgetvkvecldwtdgqiknndsaddvrtvdlkkvHeltgPvevegAepGDllvveildievleeaewGytgifdkengg 109
                 ++++ h +w    p+v +v+ g++v  + +d  +gqi+ +++++ + +++l+   +  gPv+v++AepGD+l ve+l++e+ +   wG+t   +   g+
  EEA22875.1   8 HSHHKHLKWSNKQPPVLTVSSGDVVTFDLIDSSNGQITIDSDTSSLSSFQLELADPAVGPVYVRDAEPGDALKVEVLSLEMGN---WGWT---AVVPGF 100
                 45678999***********************************************************************9986...****...7789** PP

   FmdA_AmdA 110 GflkdafpeaakaiwdlegiyassrqipgvrfrglphpGllGtapsk 156
                 G+l d ++e   +iw+++     ++  pgvr+ ++p++G++G+ap +
  EEA22875.1 101 GLLADDYTESDLKIWKFDPEAGYAELKPGVRVSLRPFLGIMGIAPCA 147
                 *********************************************76 PP

  == domain 2  score: 108.7 bits;  conditional E-value: 1.6e-35
   FmdA_AmdA 201 artvpprengGnmDiknlsrGskvylPVkveGaklsvGDlHfsqGDGEisfcg.aiemsgvvtlkvevikggmeklgiknpiflpeevep.ry..seyl 295
                   t+pp   gGn+D ++l  Gs +ylPV+v+Ga +s+GD H++qG GEi  cg aie +   +++++v k+    ++  + ++ p+++++  +  +  +
  EEA22875.1 151 FSTIPPTVVGGNIDCRDLVVGSALYLPVQVPGALFSCGDGHAAQGHGEI--CGtAIETNMKAKIRLTVCKNH-PWVQSPHLLLPPQPLASlVFpdKGQY 246
                 57***********************************************..********************8.66667777788888888344332333 PP

   FmdA_AmdA 296 sfeGisvdesgkqhyldltvAyrnallraieyLk.kfGytkeqaylllsvapvegrisgivdiPnvvatlalPldiF 371
                 + +G            dl  A+r+a + +ie+L  + G t+++ay+l sva  + +i+++vd+Pn  +t+++Pl++F
  EEA22875.1 247 ATMG---------LDPDLLQATRKATRSMIEWLVaTKGLTRSEAYILASVA-GDLKIAEVVDMPNHAVTMSMPLHVF 313
                 3344.........345999**************8789**************.89**********************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (314 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       346  (0.0192983); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.43
# Mc/sec: 2176.29
//
Query:       EEA22876.1  [L=1006]
Description: ATP-depentend DNA helicase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    7.6e-61  206.4   0.0    1.6e-56  192.2   0.0    2.8  2  UvrD_C         UvrD-like helicase C-terminal domain
    1.3e-60  205.6   0.5    3.2e-59  201.0   0.5    2.3  1  UvrD-helicase  UvrD/REP helicase N-terminal domain
    1.4e-29  103.4   0.0      3e-29  102.2   0.0    1.6  1  AAA_19         AAA domain
    1.1e-14   54.0   0.8    2.6e-14   52.8   0.1    2.1  2  UvrD_C_2       UvrD-like helicase C-terminal domain
    7.6e-07   29.0   0.0     0.0015   18.3   0.0    2.3  2  AAA_30         AAA domain
    5.8e-05   22.8   0.0     0.0013   18.4   0.0    2.3  2  AAA_12         AAA domain
     0.0017   18.2   0.4     0.0085   15.9   0.0    2.2  2  AAA_11         AAA domain
  ------ inclusion threshold ------
      0.084   13.1   0.5        2.9    8.2   0.0    2.5  2  AAA_22         AAA domain


Domain annotation for each model (and alignments):
>> UvrD_C  UvrD-like helicase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.4   0.1   0.00014      0.31     130     203 ..     123     209 ..     115     270 .. 0.65
   2 !  192.2   0.0   7.3e-60   1.6e-56       2     346 ..     276     639 ..     275     642 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00014
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxx...............xxxxxxxxxxxxxx RF
      UvrD_C 130 ialkrilkrlvlgigkatveriseelkklglsltDfikedt..leygeeFieliraleeknl...............elllkkiektaeer 203
                 +++kri+krl l+i+++ ++  ++++k  g+s +D+i+  +  +  ++eF++  r++e+                        ++++++  
  EEA22876.1 123 AIIKRIVKRLNLNIQPNPARSRISSQKAQGISWQDLIDARHpkSVDQQEFVQVYREYEAALAssnlldyddlllrcvD----LLRQHPHCV 209
                 5789*************999888**************98651155567899888888876556777777777754440....333333333 PP

  == domain 2  score: 192.2 bits;  conditional E-value: 7.3e-60
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      UvrD_C   2 vLekNyRStksLlkaankflenilnrralekekktvekgekivvleaeteeeEaekiaatikall...ekneklediavLvRsnkdadkiskaLkkegi 97 
                  Le NyRS+ s+l+ a++++e+ + r+++ k + t+  g   v+++ +t   Ea++ + +ik+     ++  k +d a+L Rs + +++i+ +L k+gi
  EEA22876.1 276 LLEDNYRSSGSILGSAEQVIEQDTARPVK-KLHPTHGVGTMPVLRKLPTAAAEAQWMVMEIKRCItltGQLLKSSDFAILLRSAALSRQIESELGKQGI 373
                 599*****************999999665.466******************************99999999**************************** PP

                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....... RF
      UvrD_C  98 pfnvvdeekfFkreeikdilaylkllankqdkialkrilkrlvlgigkatveriseelkklglsltDfikedtleygeeFieliraleeknl....... 189
                 p+++v++ +fF+r ei+ +l yl+++  ++++ al ri++ ++++ig++t++ +    +++ l l  fik+  +        l +a     +       
  EEA22876.1 374 PYRMVGGSRFFDRVEIRLLLDYLRVISHPENNDALARIINVPTRKIGDETLKSLTAGAESANLPLWTFIKDVAQGRRSCQKGLSKAA----Niglsvlv 468
                 *********************************************************************998866444333333332....13445666 PP

                 ...................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      UvrD_C 190 ...................elllkkiektaeerqalvskyadlfkelaeklaelkekseskrkkeeklenlreLysllkelekkeeeeeveeklneile 269
                                    ++ll+ + ++   r+ l + y  + ++   +++el +++     ++   ++ ++++  ++ le+ ++    ee+l ++l 
  EEA22876.1 469 glieasrqklhdcidesspRVLLEFVISKLGFREYLTATYPLDEENRWANVEELLAQAGD---SSTSYSQQDDILPEIEGLEQ-HQGHIGEEALSRFLA 563
                 666555544433333333322222233333333333333332222222222222222222...22266666777777777777.444444556****** PP

                 xxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      UvrD_C 270 iatLseseleeskkk..ekipiiTiHqAKGlEFdvVflagleegtfPsyrskkekrleEEkRlfYVaiTRAkkrLfisy 346
                 + +Ls +   e+ ++  ek++i+TiH+AKGlE++vVf+a + eg++P++r++++   +EE+Rl+YVa+TRA+  L++s+
  EEA22876.1 564 NVALSTEVTTEEGDQpqEKVTISTIHAAKGLEWPVVFVAAVYEGIIPHSRAEDS---DEERRLLYVAMTRAQALLYLSL 639
                 *****999888888889******************************9998887...9******************996 PP

>> UvrD-helicase  UvrD/REP helicase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  201.0   0.5   1.4e-62   3.2e-59       1     314 [.      10     269 ..      10     270 .. 0.92

  Alignments for each domain:
  == domain 1  score: 201.0 bits;  conditional E-value: 1.4e-62
                    SSHHHHHHHHS-SSEEEEEE-TTSSHHHHHHHHHHHHHHTSS.STGGGEEEEESSHHHHHHHHHHHHHHHHHCCHHCTT-HHHHHHHHHCTTSEEE CS
  UvrD-helicase   1 lnpeqreaiaslggpilveAsAGsGKTfvlaerilrlikeee.iepdrilvvTFTnkAaeElkeRieealkkaeqessdderlrlalqnlseanis 95 
                    ln+ qr a++s+++ + v+A +GsGKT++l++r+++l+  ++   p+++++ TFT kA++E++eR++++++ +                +s++  +
     EEA22876.1  10 LNAAQRTAVTSPSSILQVLAPPGSGKTKTLTARVAYLLSSKHaFRPQDVICCTFTIKASREMRERLTHLIGDQ---------------VVSKLVLG 90 
                    6899***********************************999899*************************987...............59****** PP

                    EHHHHHHHHHHHHHGGTTSHTTTEEECHHHHHHCCHHHHHHHHHSCHSHTTTTHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCHHHHHHHHHHH CS
  UvrD-helicase  96 TlHsfcqkilkkeanrigldpnfrildeedeedlkqqellkelleksaddslnldkkkleklikelsksrnikkeelslskskaeelrelvskake 191
                    T+Hs+c+++l ++ + igl+++f i+d++d      ++++k++++   + +ln++ + ++++                            +s  k 
     EEA22876.1  91 TFHSICRRYLVAYGHLIGLKKGFGIADSND-----GLAIIKRIVK---RLNLNIQPNPARSR----------------------------ISSQKA 150
                    ******************************.....9********8...77777777777755............................566666 PP

                    TTCCTTHHCHSSTSCSHHHHHHHHHHHHHHHHHHHHTCEEHHHHHHHHHHHHHHCHHHHHHHHHHSSEEEESSGGG-BHHHHHHHHHHHTTTTTEE CS
  UvrD-helicase 192 kqlspkelkkafekasdlqkkiaeflkeyqeqkkeenalDfsdllhallelleeneelaealrerykeiliDEyQDTnkiQyrilkllasgheelf 287
                    + +s ++l +a + +s  q+++ ++++ey+  +  +n+lD++dll++++ ll+++++ ++    +++++l+DE+QDTn iQy++++l a++++ ++
     EEA22876.1 151 QGISWQDLIDARHPKSVDQQEFVQVYREYEAALASSNLLDYDDLLLRCVDLLRQHPHCVS----NVQTVLVDEFQDTNVIQYELMNLFAAQNKRIT 242
                    677777777766677899999*********************************998665....5678**************************** PP

                    EEE-GGG--GGGGTB-THHHHHHHHHS CS
  UvrD-helicase 288 mvGDpkQsIYgFRgAdielflkkkkdf 314
                    +vGDp+QsIYgFR A+i+++ ++++++
     EEA22876.1 243 IVGDPDQSIYGFRSAEIKNLERMQRRY 269
                    *********************999987 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  102.2   0.0   1.3e-32     3e-29       1     146 []      14     255 ..      14     255 .. 0.95

  Alignments for each domain:
  == domain 1  score: 102.2 bits;  conditional E-value: 1.3e-32
      AAA_19   1 qreavealkekvllvtaGpGtGKTrvlkhivallvelgg.vkpeeillvaftgrAakelrerlaalgae.......atTiHrlal.............. 77 
                 qr av ++++++l v+a+pG+GKT++l+++va+l++ ++   p+++++++ft +A +e+rerl+ l ++         T+H++                
  EEA22876.1  14 QRTAV-TSPSSILQVLAPPGSGKTKTLTARVAYLLSSKHaFRPQDVICCTFTIKASREMRERLTHLIGDqvvsklvLGTFHSICRrylvayghliglkk 111
                 89999.**************************99876651689********************9998889*****999***9977************** PP

      AAA_19  78 .............................................................................ldfddlltealelleeaeeekk 99 
                                                                                              ld+ddll   + ll++  + + 
  EEA22876.1 112 gfgiadsndglaiikrivkrlnlniqpnparsrissqkaqgiswqdlidarhpksvdqqefvqvyreyeaalassnlLDYDDLLLRCVDLLRQ--HPHC 208
                 ******************************************************************************************985..5667 PP

      AAA_19 100 lqeeellivDEfqdvdelqyrLlkallgekkklllvGDpdQliyvfr 146
                 + + ++++vDEfqd++  qy+L++  + ++k++++vGDpdQ+iy fr
  EEA22876.1 209 VSNVQTVLVDEFQDTNVIQYELMNLFAAQNKRITIVGDPDQSIYGFR 255
                 76666**********************999**************997 PP

>> UvrD_C_2  UvrD-like helicase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.8   0.1       2.6   5.9e+03       6      16 ..     146     156 ..     145     157 .. 0.81
   2 !   52.8   0.1   1.2e-17   2.6e-14       2      51 ..     583     637 ..     582     638 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.8 bits;  conditional E-value: 2.6
    UvrD_C_2   6 tihkaQGsefp 16 
                 + +kaQG  ++
  EEA22876.1 146 SSQKAQGISWQ 156
                 679****9885 PP

  == domain 2  score: 52.8 bits;  conditional E-value: 1.2e-17
    UvrD_C_2   2 ayaltihkaQGsefpaVivfdpd..laaarmgel...rrrlLYtavTRAreklil 51 
                 ++++tih a+G+e+p+V+v++++     + + e+    rrlLY+a+TRA++ l+l
  EEA22876.1 583 VTISTIHAAKGLEWPVVFVAAVYegIIPHSRAEDsdeERRLLYVAMTRAQALLYL 637
                 689****************998843333333333666****************98 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.3   0.0   6.6e-07    0.0015       4      67 ..      12      76 ..       9      95 .. 0.84
   2 !    8.3   0.0   0.00079       1.8      87     128 ..     209     250 ..     176     308 .. 0.75

  Alignments for each domain:
  == domain 1  score: 18.3 bits;  conditional E-value: 6.6e-07
      AAA_30  4 aeQaaavealltsgdrvavltGpAGtGKttalkalreaweaag.....grviglAptgkaAkvLaeelg 67
                a    a ++++ts+  +  + +p+G+GKt +l+a ++ + +++     ++vi ++ t ka+++++e l 
  EEA22876.1 12 A----AQRTAVTSPSSILQVLAPPGSGKTKTLTARVAYLLSSKhafrpQDVICCTFTIKASREMRERLT 76
                4....44556689999999*************9998777777558999*****************9765 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.00079
      AAA_30  87 epg.tllivDEagmvdtkqlaallkaaekagakvilvGDerQl 128
                  ++ + ++vDE   ++  q + l++  ++++ ++ +vGD++Q 
  EEA22876.1 209 VSNvQTVLVDEFQDTNVIQYE-LMNLFAAQNKRITIVGDPDQS 250
                 344499******999999986.55666666************5 PP

>> AAA_12  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0     0.076   1.7e+02       6      32 ..     262     289 ..     259     301 .. 0.85
   2 !   18.4   0.0   5.7e-07    0.0013     127     193 ..     567     636 ..     509     638 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.076
      AAA_12   6 ferllkke.kekvvlLdtqYRmhpeIsr 32 
                 +er+++++ +++vvlL+ +YR+  +I+ 
  EEA22876.1 262 LERMQRRYpNTSVVLLEDNYRSSGSILG 289
                 6899999988999*********999975 PP

  == domain 2  score: 18.4 bits;  conditional E-value: 5.7e-07
      AAA_12 127 lkkklkekeeeksekeievntvdgfQGrekdviilslVRsn...ekkeigflkderrlNValTRAkskli 193
                 l+ +++++e ++++++++++t+ +  G e+ v+++ +V      +++     +++r l Va+TRA+  l+
  EEA22876.1 567 LSTEVTTEEGDQPQEKVTISTIHAAKGLEWPVVFVAAVYEGiipHSRAEDSDEERRLLYVAMTRAQALLY 636
                 5666777888889999************************8875333333456777789*******9886 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.0   3.8e-06    0.0085       2      76 ..      10      77 ..       9      91 .. 0.81
   2 ?   -1.3   0.1      0.65   1.5e+03     217     253 ..     211     249 ..     200     249 .. 0.59

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 3.8e-06
      AAA_11  2 lndsqreaiksalseseitliqGPPGtgKTktivellsqllsrrkseeeksakpriLvCapSNaAvDellerllr 76
                ln+ qr+a++s+ s   i  +  PPG+gKTkt+++ +++ll    s++++ +++ +  C+ + +A  e+ erl  
  EEA22876.1 10 LNAAQRTAVTSPSS---ILQVLAPPGSGKTKTLTARVAYLL----SSKHAFRPQDVICCTFTIKASREMRERLTH 77
                67777777766644...455889*****************4....467899*********999999999999877 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.65
      AAA_11 217 kfdvviIDEAaqa..vEpstliPlrlgakkvvLvGDpkQ 253
                 ++++v++DE      +  + +  +  + k++ +vGDp Q
  EEA22876.1 211 NVQTVLVDEFQDTnvIQYELMNLFAAQNKRITIVGDPDQ 249
                 56666666653331033333333444557999****999 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   0.0    0.0013       2.9       6      67 ..      23      82 ..      18     109 .. 0.71
   2 ?    2.5   0.1     0.075   1.7e+02      58     110 ..     173     232 ..     124     249 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0013
      AAA_22  6 gilvvtGesGtGKTtll.rrlleqldeeakaeeerpevvfvtlpsstsskdllrellralgle 67
                +il v +++G+GKT +l +r+++ l   +k++ ++ +v+ +t + +  s++++++l + +g++
  EEA22876.1 23 SILQVLAPPGSGKTKTLtARVAYLL--SSKHAFRPQDVICCTFTIKA-SREMRERLTHLIGDQ 82
                678899********76615666665..46677788888877777776.677777777777665 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.075
      AAA_22  58 rellralglelka.erlsseellealeqalrarav....ielliiDEaqhlr..seeale 110
                  ++ r+++  l + + l+ ++ll ++ + lr++      ++ +++DE+q  +  + e+++
  EEA22876.1 173 VQVYREYEAALASsNLLDYDDLLLRCVDLLRQHPHcvsnVQTVLVDEFQDTNviQYELMN 232
                 455566666555566778888889999999998889999**********98443333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1006 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       621  (0.0346366); expected 358.6 (0.02)
Passed bias filter:                      430  (0.0239835); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.76u 0.29s 00:00:01.05 Elapsed: 00:00:00.47
# Mc/sec: 6447.31
//
Query:       EEA22877.1  [L=259]
Description: MYND domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
      3e-12   46.4  18.0    5.4e-12   45.6  18.0    1.4  1  zf-MYND      MYND finger
  ------ inclusion threshold ------
      0.058   13.7  16.2      0.092   13.1  14.9    2.1  2  zf-C6H2      zf-MYND-like zinc finger, mRNA-binding
       0.73    9.9  10.8        4.3    7.4   0.7    2.4  2  NCD3G        Nine Cysteines Domain of family 3 GPCR
        1.7    9.1  11.0        3.2    8.2  11.0    1.4  1  Rhodanese_C  Rhodanase C-terminal


Domain annotation for each model (and alignments):
>> zf-MYND  MYND finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.6  18.0   1.2e-15   5.4e-12       1      38 []      18      59 ..      18      59 .. 0.97

  Alignments for each domain:
  == domain 1  score: 45.6 bits;  conditional E-value: 1.2e-15
                -TTT--.....B-SCE-TTTS-SEESSHHHHHHCHHHHCCCH CS
     zf-MYND  1 CavCgk....aealkkCagCksvfYCskeCqradwksHkteC 38
                Ca+C k    ++alk+Ca+Ck++fYCs++Cq+++wk+Hk+ C
  EEA22877.1 18 CANCAKastsDNALKRCAKCKTTFYCSRDCQKSHWKTHKKVC 59
                ******999999999**************************9 PP

>> zf-C6H2  zf-MYND-like zinc finger, mRNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1  14.9     2e-05     0.092      12      44 ..      30      58 ..      12      61 .. 0.68
   2 ?   -3.3   0.0       2.6   1.2e+04      18      24 ..     183     189 ..     180     193 .. 0.64

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2e-05
     zf-C6H2 12 s.LqCptClklgikesfFCsqeCFkknwkkHkal 44
                +  +C +C   +  ++f+Cs++C k+ wk+Hk++
  EEA22877.1 30 AlKRCAKC---K--TTFYCSRDCQKSHWKTHKKV 58
                32346666...4..46****************97 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 2.6
     zf-C6H2  18 Clklgik 24 
                 C++lg++
  EEA22877.1 183 CMQLGMR 189
                 6666654 PP

>> NCD3G  Nine Cysteines Domain of family 3 GPCR
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.4   3.2   0.00097       4.4      27      51 ..      17      42 ..      15      42 .. 0.86
   2 ?    7.4   0.7   0.00096       4.3       5      19 ..      43      57 ..      40      61 .. 0.88

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.00097
       NCD3G 27 dCvpCpegeis.tdseeCtkCpedew 51
                +C +C++ + s +  ++C kC+ +++
  EEA22877.1 17 HCANCAKASTSdNALKRCAKCKTTFY 42
                7********99557888****98765 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.00096
       NCD3G  5 CsesCppgfrkkvqe 19
                Cs++C++ ++k++++
  EEA22877.1 43 CSRDCQKSHWKTHKK 57
                ************986 PP

>> Rhodanese_C  Rhodanase C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2  11.0   0.00071       3.2      19      63 ..      16      59 ..       5      62 .. 0.82

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.00071
  Rhodanese_C 19 gkCieCgkpvdelr.krnCanedCnelvlvCeeCaeklkgvcseeC 63
                  +C  C k +++ +  ++Ca  +C++ + ++++C++++ ++ ++ C
   EEA22877.1 16 QHCANCAKASTSDNaLKRCA--KCKTTFYCSRDCQKSHWKTHKKVC 59
                 689999988775556999*8..7*************9988766666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (259 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1046  (0.0583412); expected 358.6 (0.02)
Passed bias filter:                      428  (0.0238719); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.49
# Mc/sec: 1600.71
//
Query:       EEA22878.1  [L=1440]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.4e-69  230.7   0.3    2.4e-15   56.9   0.0    7.8  6  Ank_2      Ankyrin repeats (3 copies)
    1.9e-47  153.7   2.1    0.00027   21.2   0.0   13.9 14  Ank_3      Ankyrin repeat
    1.8e-45  151.4   4.1    0.00042   20.6   0.0   13.6 13  Ank        Ankyrin repeat
    5.1e-44  148.1   7.5    2.2e-07   31.3   0.2   10.4 12  Ank_4      Ankyrin repeats (many copies)
    1.6e-43  146.1   6.2    3.8e-07   30.3   0.0   11.0 11  Ank_5      Ankyrin repeats (many copies)
    6.3e-13   48.5   0.4    1.2e-12   47.6   0.4    1.5  1  PNP_UDP_1  Phosphorylase superfamily
    1.7e-06   28.1   0.0    3.6e-06   27.0   0.0    1.5  1  NACHT      NACHT domain
     0.0056   17.1   0.0      0.026   14.9   0.0    2.2  1  AAA_16     AAA ATPase domain
  ------ inclusion threshold ------
      0.012   15.9   0.0      0.068   13.5   0.0    2.1  1  AAA_22     AAA domain


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.5   0.1   2.1e-15   4.3e-12       3      79 ..     900     991 ..     898     997 .. 0.84
   2 !   56.9   0.0   1.2e-18   2.4e-15       1      80 [.    1002    1092 ..    1002    1094 .. 0.84
   3 !   20.7   0.0   2.3e-07   0.00046      30      82 ..    1102    1161 ..    1096    1162 .. 0.81
   4 !   38.5   0.1   6.6e-13   1.3e-09      25      76 ..    1164    1222 ..    1157    1229 .. 0.84
   5 !   19.2   0.0   6.7e-07    0.0013      25      75 ..    1197    1281 ..    1190    1323 .. 0.72
   6 !   50.5   0.0   1.2e-16   2.3e-13       1      81 [.    1326    1416 ..    1326    1418 .. 0.87

  Alignments for each domain:
  == domain 1  score: 46.5 bits;  conditional E-value: 2.1e-15
       Ank_2   3 lAakngnlelvklLl.egadpn...k.....ngktaLhyAakngnleivklLleh.....adndgrtpLhyAarsghleivklLlek.gadi 79 
                 +Aakng+ +l++l l +g d++   +     + + aLh+A k g +++++lLl+      +d++g+t+Lh+Aa++gh++++ lLl++ g ++
  EEA22878.1 900 WAAKNGHIPLLELALtSGRDIReicNlplvdERLPALHVASKMGLTDVIRLLLSMcqlnlQDEEGYTALHHAASKGHEDVIVLLLNSgGTKV 991
                 89****99********99998766425567799********************94456677799*************999999997755554 PP

  == domain 2  score: 56.9 bits;  conditional E-value: 1.2e-18
       Ank_2    1 LhlAakngnlelvklLl.egadpn...k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadin 80  
                  L lAa++g++++v  L    a+++   + + +t+L  Aa+ng++ +v++Ll+        d  g+tpL +A+ + hl++v+lLle+ga++ 
  EEA22878.1 1002 LWLAANHGHSDIVWVLTqGQANIEvteSsTQRTPLSQAARNGHRAVVEFLLQRganleaKDAGGWTPLSWAITNEHLDTVELLLERGANPA 1092
                  6789999*99******954455556552799********************966455544588************************9985 PP

  == domain 3  score: 20.7 bits;  conditional E-value: 2.3e-07
       Ank_2   30 LhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlekgadinlk 82  
                  L +Aak g+  i  lL ++       +d++g t L +A++s++lei k+Ll++ga+ +++
  EEA22878.1 1102 LLWAAKTGHAAITGLLAANsetdlntTDDKGLTGLWLAVQSQNLEITKILLDRGASRETR 1161
                  559*****9888888887667676655599*********************999986655 PP

  == domain 4  score: 38.5 bits;  conditional E-value: 6.6e-13
       Ank_2   25 ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlek.g 76  
                  +g+t+L +Aa+n ++ +  lLl++      +d++ rt++++A++++h+e+vklLl++ g
  EEA22878.1 1164 DGQTPLLWAARNKHEALTNLLLKKgaashaQDKYERTAIFWAVENSHEEMVKLLLDQfG 1222
                  79***********98889****9666666888***********************7643 PP

  == domain 5  score: 19.2 bits;  conditional E-value: 6.7e-07
       Ank_2   25 ngktaLhyAakngnleivklLleh..........................adnd..........grtpLhyAarsghleivklLlek 75  
                   ++ta+++A++n ++e+vklLl++                          a  d           +tpL  A+r++++ +++ L+e+
  EEA22878.1 1197 YERTAIFWAVENSHEEMVKLLLDQfgdyagknrllniiplqalqtrtddtA--DlvlgetgdsgDETPLLSAVRKSYELLAQRLMER 1281
                  568999999999999999999984445555556656666666555533331..0333333334356899999988887777777765 PP

  == domain 6  score: 50.5 bits;  conditional E-value: 1.2e-16
       Ank_2    1 LhlAakngnlelvklLl.egadpn..k.ngktaLhyAakngnleivklLleh......adndgrtpLhyAarsghleivklLlekgadinl 81  
                  L  Aak+gn +  klL+ egad++  +  g+t+L++Aa+ng+  +v++L +        d+ g tpL +A+++ h  +v+lL+  ga+i +
  EEA22878.1 1326 LLRAAKQGNGDSAKLLVdEGADIHtrSvYGETPLWWAARNGDAMLVEFLYNRgadiesKDKFGLTPLSWAVENRHWSVVELLVGWGANIRA 1416
                  56899*99889*************8649*************86669****977555555599*********************88999976 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.0      0.29   5.8e+02       6      29 ..     898     920 ..     894     922 .. 0.82
   2 ?    4.6   0.1     0.033        65       4      23 ..     934     953 ..     931     957 .. 0.91
   3 !   18.8   0.0     8e-07    0.0016       1      30 [.     963     992 ..     963     993 .. 0.88
   4 ?    5.1   0.0     0.022        45       4      29 ..    1000    1024 ..     997    1026 .. 0.77
   5 !   21.2   0.0   1.3e-07   0.00027       2      30 ..    1032    1059 ..    1031    1060 .. 0.93
   6 !   17.5   0.0     2e-06     0.004       2      30 ..    1065    1092 ..    1064    1093 .. 0.94
   7 ?   -2.4   0.0       6.1   1.2e+04       5      30 ..    1101    1126 ..    1100    1127 .. 0.74
   8 ?    5.1   0.0     0.022        45       2      27 ..    1132    1156 ..    1131    1159 .. 0.92
   9 !   12.8   0.0     7e-05      0.14       1      28 [.    1164    1190 ..    1164    1193 .. 0.90
  10 !   11.1   0.0   0.00024      0.48       2      27 ..    1198    1222 ..    1197    1225 .. 0.87
  11 ?   -2.5   0.0       6.5   1.3e+04       3      13 ..    1260    1270 ..    1259    1285 .. 0.75
  12 ?    3.9   0.0     0.055   1.1e+02       6      30 ..    1326    1349 ..    1323    1350 .. 0.91
  13 !   18.4   0.0   1.1e-06    0.0021       1      29 [.    1354    1381 ..    1354    1383 .. 0.95
  14 !   15.0   0.0   1.3e-05     0.027       2      30 ..    1388    1415 ..    1387    1416 .. 0.94

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.29
       Ank_3   6 LhlAarsgnleivkfLlenkgadv 29 
                 + +Aa++g+++++++ l   g d+
  EEA22878.1 898 FGWAAKNGHIPLLELALT-SGRDI 920
                 459********9999998.78777 PP

  == domain 2  score: 4.6 bits;  conditional E-value: 0.033
       Ank_3   4 tpLhlAarsgnleivkfLle 23 
                  +Lh+A + g ++++++Ll 
  EEA22878.1 934 PALHVASKMGLTDVIRLLLS 953
                 58****************96 PP

  == domain 3  score: 18.8 bits;  conditional E-value: 8e-07
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvn 30 
                 +G+t+Lh+Aa+ g+ +++ +Ll+  g  v+
  EEA22878.1 963 EGYTALHHAASKGHEDVIVLLLNSGGTKVD 992
                 69**************99999997787776 PP

  == domain 4  score: 5.1 bits;  conditional E-value: 0.022
       Ank_3    4 tpLhlAarsgnleivkfLlenkgadv 29  
                  tpL lAa +g+ + + + l +  a++
  EEA22878.1 1000 TPLWLAANHGHSD-IVWVLTQGQANI 1024
                  9************.666666466665 PP

  == domain 5  score: 21.2 bits;  conditional E-value: 1.3e-07
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                  ++tpL +Aar+g+ ++v+fLl+ +ga++ 
  EEA22878.1 1032 QRTPLSQAARNGHRAVVEFLLQ-RGANLE 1059
                  69********************.9**985 PP

  == domain 6  score: 17.5 bits;  conditional E-value: 2e-06
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                  G+tpL +A+ + +l+ v++Lle +ga++ 
  EEA22878.1 1065 GWTPLSWAITNEHLDTVELLLE-RGANPA 1092
                  9*********************.9**985 PP

  == domain 7  score: -2.4 bits;  conditional E-value: 6.1
       Ank_3    5 pLhlAarsgnleivkfLlenkgadvn 30  
                  +L +Aa+ g+ +i  +L  n   d+n
  EEA22878.1 1101 LLLWAAKTGHAAITGLLAANSETDLN 1126
                  6889**99999877766666666665 PP

  == domain 8  score: 5.1 bits;  conditional E-value: 0.022
       Ank_3    2 GetpLhlAarsgnleivkfLlenkga 27  
                  G t L lA+ s+nlei k Ll+ +ga
  EEA22878.1 1132 GLTGLWLAVQSQNLEITKILLD-RGA 1156
                  8899******************.898 PP

  == domain 9  score: 12.8 bits;  conditional E-value: 7e-05
       Ank_3    1 nGetpLhlAarsgnleivkfLlenkgad 28  
                  +G+tpL +Aar+ + ++  +Ll+ kga 
  EEA22878.1 1164 DGQTPLLWAARNKHEALTNLLLK-KGAA 1190
                  69**************9999999.8875 PP

  == domain 10  score: 11.1 bits;  conditional E-value: 0.00024
       Ank_3    2 GetpLhlAarsgnleivkfLlenkga 27  
                   +t++++A+++ + e+vk+Ll++   
  EEA22878.1 1198 ERTAIFWAVENSHEEMVKLLLDQ-FG 1222
                  69*******************94.43 PP

  == domain 11  score: -2.5 bits;  conditional E-value: 6.5
       Ank_3    3 etpLhlAarsg 13  
                  etpL  A+r  
  EEA22878.1 1260 ETPLLSAVRKS 1270
                  79*****9976 PP

  == domain 12  score: 3.9 bits;  conditional E-value: 0.055
       Ank_3    6 LhlAarsgnleivkfLlenkgadvn 30  
                  L +Aa++gn + +k+L++  gad++
  EEA22878.1 1326 LLRAAKQGNGDSAKLLVD-EGADIH 1349
                  889*******99******.8***97 PP

  == domain 13  score: 18.4 bits;  conditional E-value: 1.1e-06
       Ank_3    1 nGetpLhlAarsgnleivkfLlenkgadv 29  
                  +GetpL +Aar+g+  +v+fL + +gad+
  EEA22878.1 1354 YGETPLWWAARNGDAMLVEFLYN-RGADI 1381
                  79*************99******.9***9 PP

  == domain 14  score: 15.0 bits;  conditional E-value: 1.3e-05
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadvn 30  
                  G tpL +A+++ + ++v++L+  +ga+++
  EEA22878.1 1388 GLTPLSWAVENRHWSVVELLVG-WGANIR 1415
                  99********************.9***97 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       2.3   4.6e+03      20      31 ..     712     724 ..     703     724 .. 0.85
   2 !   10.7   0.1   0.00029      0.57       5      31 ..     935     961 ..     935     962 .. 0.87
   3 !   20.6   0.0   2.1e-07   0.00042       2      24 ..     964     987 ..     963     996 .. 0.83
   4 !    8.1   0.0     0.002       3.9       3      28 ..     999    1025 ..     998    1029 .. 0.86
   5 !   17.8   0.0   1.7e-06    0.0034       3      31 ..    1033    1062 ..    1032    1063 .. 0.93
   6 !   19.9   0.0   3.5e-07    0.0007       2      28 ..    1065    1092 ..    1064    1094 .. 0.94
   7 ?   -0.6   0.1       1.1   2.2e+03       7      31 ..    1103    1129 ..    1100    1130 .. 0.73
   8 ?    4.0   0.0     0.038        75       2      26 ..    1132    1157 ..    1131    1163 .. 0.83
   9 !   15.6   0.1   8.2e-06     0.016       1      31 [.    1164    1195 ..    1164    1196 .. 0.87
  10 !    6.1   0.0    0.0084        17       2      24 ..    1198    1222 ..    1197    1232 .. 0.85
  11 ?    1.4   0.0      0.25     5e+02       9      29 ..    1329    1350 ..    1324    1353 .. 0.77
  12 !   14.9   0.0   1.4e-05     0.028       1      32 []    1354    1386 ..    1354    1386 .. 0.91
  13 !   15.3   0.0     1e-05     0.021       2      31 ..    1388    1418 ..    1387    1419 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 2.3
                 HHH.TTTSTTCBT CS
         Ank  20 lLL.hGAnlnald 31 
                  L+ +GAnl a+d
  EEA22878.1 712 VLIgCGANLVAVD 724
                 59999***97776 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 0.00029
                 HHHHHHHHTTHHHHHHHHTT.TSTTCBT CS
         Ank   5 PLHlAatngkkriiklLLhG.Anlnald 31 
                 +LH+A+  g +++i+lLL + + ln++d
  EEA22878.1 935 ALHVASKMGLTDVIRLLL-SmCQLNLQD 961
                 8*****99**********.546699998 PP

  == domain 3  score: 20.6 bits;  conditional E-value: 2.1e-07
                 SBBHHHHHHHHTTHHHHHHHH.TT CS
         Ank   2 GnTPLHlAatngkkriiklLL.hG 24 
                 G+T+LH Aa+ g++++i lLL +G
  EEA22878.1 964 GYTALHHAASKGHEDVIVLLLnSG 987
                 9********************775 PP

  == domain 4  score: 8.1 bits;  conditional E-value: 0.002
                  BBHHHHHHHHTTHHHHHHHHTT.TSTT CS
         Ank    3 nTPLHlAatngkkriiklLLhG.Anln 28  
                   TPL lAa+ g+ +i+  L +G An+ 
  EEA22878.1  999 VTPLWLAANHGHSDIVWVLTQGqANIE 1025
                  5***************88778888875 PP

  == domain 5  score: 17.8 bits;  conditional E-value: 1.7e-06
                  BBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    3 nTPLHlAatngkkriiklLL.hGAnlnald 31  
                  +TPL  Aa+ng+  ++++LL +GAnl a+d
  EEA22878.1 1033 RTPLSQAARNGHRAVVEFLLqRGANLEAKD 1062
                  6*******************779*****99 PP

  == domain 6  score: 19.9 bits;  conditional E-value: 3.5e-07
                  SBBHHHHHHHHTTHHHHHHHH.TTTSTT CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAnln 28  
                  G+TPL +A+tn +++ ++lLL +GAn++
  EEA22878.1 1065 GWTPLSWAITNEHLDTVELLLeRGANPA 1092
                  9********************99***96 PP

  == domain 7  score: -0.6 bits;  conditional E-value: 1.1
                  HHHHHHTTHHHHHHHH.TT.TSTTCBT CS
         Ank    7 HlAatngkkriiklLL.hG.Anlnald 31  
                   +Aa  g++ i+ lL  ++  +ln +d
  EEA22878.1 1103 LWAAKTGHAAITGLLAaNSeTDLNTTD 1129
                  4799889999***66564457898887 PP

  == domain 8  score: 4.0 bits;  conditional E-value: 0.038
                  SBBHHHHHHHHTTHHHHHHHH.TTTS CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAn 26  
                  G T L lA++  +++i+k LL +GA+
  EEA22878.1 1132 GLTGLWLAVQSQNLEITKILLdRGAS 1157
                  667799***9999********77997 PP

  == domain 9  score: 15.6 bits;  conditional E-value: 8.2e-06
                  TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    1 dGnTPLHlAatngkkriiklLL.hGAnlnald 31  
                  dG TPL +Aa+n+++  + lLL +GA  +a+d
  EEA22878.1 1164 DGQTPLLWAARNKHEALTNLLLkKGAASHAQD 1195
                  8*********************8896457777 PP

  == domain 10  score: 6.1 bits;  conditional E-value: 0.0084
                  SBBHHHHHHHHTTHHHHHHHH.T.T CS
         Ank    2 GnTPLHlAatngkkriiklLL.h.G 24  
                   +T+  +A+ n +++++klLL + G
  EEA22878.1 1198 ERTAIFWAVENSHEEMVKLLLdQfG 1222
                  579999***999*********6556 PP

  == domain 11  score: 1.4 bits;  conditional E-value: 0.25
                  HHHHTTHHHHHHHH.TTTSTTC CS
         Ank    9 AatngkkriiklLL.hGAnlna 29  
                  Aa  g+ + +klL+  GA+++ 
  EEA22878.1 1329 AAKQGNGDSAKLLVdEGADIHT 1350
                  7766666799****77***975 PP

  == domain 12  score: 14.9 bits;  conditional E-value: 1.4e-05
                  TSBBHHHHHHHHTTHHHHHHHH.TTTSTTCBTT CS
         Ank    1 dGnTPLHlAatngkkriiklLL.hGAnlnaldn 32  
                  +G TPL +Aa+ng++  +++L  +GA++ ++d+
  EEA22878.1 1354 YGETPLWWAARNGDAMLVEFLYnRGADIESKDK 1386
                  69*****************888779***99985 PP

  == domain 13  score: 15.3 bits;  conditional E-value: 1e-05
                  SBBHHHHHHHHTTHHHHHHHH.TTTSTTCBT CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAnlnald 31  
                  G TPL +A+ n ++++++lL+  GAn+ a d
  EEA22878.1 1388 GLTPLSWAVENRHWSVVELLVgWGANIRAPD 1418
                  89*******9999********668***9988 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.9   0.1    0.0024       4.9       7      55 .]     900     952 ..     895     952 .. 0.84
   2 !   31.3   0.2   1.1e-10   2.2e-07       2      55 .]     933     984 ..     932     984 .. 0.93
   3 !   26.6   0.0   3.2e-09   6.4e-06       2      51 ..     965    1014 ..     964    1017 .. 0.90
   4 !   29.1   0.0   5.5e-10   1.1e-06       2      55 .]    1033    1085 ..    1032    1085 .. 0.97
   5 !   17.2   0.0   2.9e-06    0.0058       3      54 ..    1067    1117 ..    1067    1118 .. 0.88
   6 !   12.4   0.0   9.3e-05      0.18       4      55 .]    1101    1152 ..    1099    1152 .. 0.87
   7 !   18.2   0.1   1.3e-06    0.0027       6      55 .]    1137    1185 ..    1134    1185 .. 0.91
   8 !   22.8   0.1   5.2e-08    0.0001       3      55 .]    1167    1218 ..    1165    1218 .. 0.97
   9 !   13.5   0.0   4.1e-05     0.081       1      23 [.    1198    1220 ..    1198    1272 .. 0.70
  10 !   25.8   0.0   5.7e-09   1.1e-05       5      54 ..    1326    1374 ..    1323    1374 .. 0.92
  11 !   15.2   0.0   1.3e-05     0.025      16      55 .]    1370    1408 ..    1368    1408 .. 0.95
  12 !    7.8   0.0    0.0026       5.2       2      41 ..    1389    1427 ..    1389    1428 .. 0.92

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0024
       Ank_4   7 yaaisgrlelvrlLlekgad....inaqdnrsGetalhiAakrgnveilklLl 55 
                 +aa+ g+++l++l l +g d    +n  + ++ ++alh A k+g  ++++lLl
  EEA22878.1 900 WAAKNGHIPLLELALTSGRDireiCNLPLVDERLPALHVASKMGLTDVIRLLL 952
                 7999***********88877446555555588999*********999999997 PP

  == domain 2  score: 31.3 bits;  conditional E-value: 1.1e-10
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 l+aLh a ++g ++++rlLl +  ++n q +++G talh+Aa++g+ +++ lLl
  EEA22878.1 933 LPALHVASKMGLTDVIRLLL-SMCQLNLQ-DEEGYTALHHAASKGHEDVIVLLL 984
                 789*****************.557899**.********************9997 PP

  == domain 3  score: 26.6 bits;  conditional E-value: 3.2e-09
       Ank_4    2 ltaLhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAakrgnveil 51  
                  +taLh+aa++g+++++ lLl++ g  ++   ++ + t+l+ Aa +g+ +i+
  EEA22878.1  965 YTALHHAASKGHEDVIVLLLNSgGTKVDIP-SKTQVTPLWLAANHGHSDIV 1014
                  79******************9966777776.789*************9987 PP

  == domain 4  score: 29.1 bits;  conditional E-value: 5.5e-10
       Ank_4    2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  +t+L +aa  g+  +v++Ll++ga++ a  ++ G+t+l  A+ +++++ ++lLl
  EEA22878.1 1033 RTPLSQAARNGHRAVVEFLLQRGANLEAK-DAGGWTPLSWAITNEHLDTVELLL 1085
                  89**************************9.***********************8 PP

  == domain 5  score: 17.2 bits;  conditional E-value: 2.9e-06
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54  
                  t+L +a+  ++l++v+lLle+ga++ +    +  ++l  Aak+g+  i+ lL
  EEA22878.1 1067 TPLSWAITNEHLDTVELLLERGANPACK-FPNKGPLLLWAAKTGHAAITGLL 1117
                  7999********************9888.556899*********98877665 PP

  == domain 6  score: 12.4 bits;  conditional E-value: 9.3e-05
       Ank_4    4 aLhyaaisgrlelvrlLlek.gadinaqdnrsGetalhiAakrgnveilklLl 55  
                  +L +aa+ g+  +  lL ++   d+n + ++ G+t l+ A++  n+ei+k Ll
  EEA22878.1 1101 LLLWAAKTGHAAITGLLAANsETDLNTT-DDKGLTGLWLAVQSQNLEITKILL 1152
                  57788888888888899977469*****.999******************997 PP

  == domain 7  score: 18.2 bits;  conditional E-value: 1.3e-06
       Ank_4    6 hyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                    a++s++le+ ++Ll++ga+   + +++G+t+l  Aa++ +   + lLl
  EEA22878.1 1137 WLAVQSQNLEITKILLDRGASRETR-DADGQTPLLWAARNKHEALTNLLL 1185
                  56888****************8888.****************99988886 PP

  == domain 8  score: 22.8 bits;  conditional E-value: 5.2e-08
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  t+L +aa   ++ l  lLl kga  +aq +++ +ta+  A+ +++ e++klLl
  EEA22878.1 1167 TPLLWAARNKHEALTNLLLKKGAASHAQ-DKYERTAIFWAVENSHEEMVKLLL 1218
                  899*******************9999*9.***********************8 PP

  == domain 9  score: 13.5 bits;  conditional E-value: 4.1e-05
       Ank_4    1 eltaLhyaaisgrlelvrlLlek 23  
                  e+ta+++a++ +++e+v+lLl++
  EEA22878.1 1198 ERTAIFWAVENSHEEMVKLLLDQ 1220
                  689******************54 PP

  == domain 10  score: 25.8 bits;  conditional E-value: 5.7e-09
       Ank_4    5 LhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklL 54  
                  L +aa++g+ ++++lL++ gadi+ + + +Get+l+ Aa++g+   +++L
  EEA22878.1 1326 LLRAAKQGNGDSAKLLVDEGADIHTR-SVYGETPLWWAARNGDAMLVEFL 1374
                  789***********************.***************97777776 PP

  == domain 11  score: 15.2 bits;  conditional E-value: 1.3e-05
       Ank_4   16 lvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  lv++L+++gadi    ++ G+t+l  A+ + + ++++lL+
  EEA22878.1 1370 LVEFLYNRGADIESK-DKFGLTPLSWAVENRHWSVVELLV 1408
                  699***********8.*********************996 PP

  == domain 12  score: 7.8 bits;  conditional E-value: 0.0026
       Ank_4    2 ltaLhyaaisgrlelvrlLlekgadinaqdnrsGetalhi 41  
                  lt+L +a++  +  +v+lL+  ga+i a  ++sG+t+l +
  EEA22878.1 1389 LTPLSWAVENRHWSVVELLVGWGANIRAP-DKSGQTPLSR 1427
                  5899************************8.*******955 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.0      0.58   1.2e+03      22      48 ..     900     924 ..     900     931 .. 0.78
   2 ?    3.5   0.0     0.047        93      19      36 ..     935     952 ..     925     956 .. 0.91
   3 !   20.7   0.1   1.9e-07   0.00037       7      36 ..     955     984 ..     951     991 .. 0.90
   4 !    7.1   0.0    0.0036       7.1      12      47 ..     994    1029 ..     987    1032 .. 0.79
   5 !   28.5   0.0   6.6e-10   1.3e-06      11      53 ..    1026    1069 ..    1016    1070 .. 0.84
   6 !    9.9   0.0   0.00046      0.92      16      42 ..    1066    1091 ..    1064    1094 .. 0.89
   7 !   24.6   0.0   1.2e-08   2.3e-05       6      53 ..    1122    1169 ..    1116    1172 .. 0.92
   8 ?    5.3   0.0     0.013        26       1      36 [.    1184    1218 ..    1184    1228 .. 0.91
   9 !   12.6   0.0   6.5e-05      0.13      20      53 ..    1326    1359 ..    1319    1359 .. 0.91
  10 !   30.3   0.0   1.9e-10   3.8e-07       1      53 [.    1341    1392 ..    1340    1393 .. 0.97
  11 !   27.7   0.0   1.2e-09   2.4e-06       7      54 ..    1379    1426 ..    1377    1428 .. 0.94

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 0.58
       Ank_5  22 vAakygaadvvrlLlargadlnltdsr 48 
                 +Aak+g+ ++++l l   + +++++ +
  EEA22878.1 900 WAAKNGHIPLLELAL--TSGRDIREIC 924
                 69***********99..6666655555 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.047
       Ank_5  19 pLhvAakygaadvvrlLl 36 
                 +LhvA+k g  dv+rlLl
  EEA22878.1 935 ALHVASKMGLTDVIRLLL 952
                 7****************9 PP

  == domain 3  score: 20.7 bits;  conditional E-value: 1.9e-07
       Ank_5   7 advnrldgggntpLhvAakygaadvvrlLl 36 
                 +++n +d++g+t+Lh+Aa++g+ dv+ lLl
  EEA22878.1 955 CQLNLQDEEGYTALHHAASKGHEDVIVLLL 984
                 589************************999 PP

  == domain 4  score: 7.1 bits;  conditional E-value: 0.0036
       Ank_5   12 ldgggntpLhvAakygaadvvrlLlargadlnltds 47  
                  + +  +tpL +Aa++g++d+v +L   +a++ +t+s
  EEA22878.1  994 PSKTQVTPLWLAANHGHSDIVWVLTQGQANIEVTES 1029
                  567789***************877777777666665 PP

  == domain 5  score: 28.5 bits;  conditional E-value: 6.6e-10
       Ank_5   11 rldgggn.tpLhvAakygaadvvrlLlargadlnltdsrGltal 53  
                   ++   + tpL +Aa++g+  vv++Ll rga+l ++d+ G+t+l
  EEA22878.1 1026 VTESSTQrTPLSQAARNGHRAVVEFLLQRGANLEAKDAGGWTPL 1069
                  55544445***********************************8 PP

  == domain 6  score: 9.9 bits;  conditional E-value: 0.00046
       Ank_5   16 gntpLhvAakygaadvvrlLlargadl 42  
                  + tpL +A+ + ++d v+lLl+rga++
  EEA22878.1 1066 W-TPLSWAITNEHLDTVELLLERGANP 1091
                  4.*******************999986 PP

  == domain 7  score: 24.6 bits;  conditional E-value: 1.2e-08
       Ank_5    6 padvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltal 53  
                    d+n++d +g t L +A+  +++++ ++Ll+rga++ ++d++G+t+l
  EEA22878.1 1122 ETDLNTTDDKGLTGLWLAVQSQNLEITKILLDRGASRETRDADGQTPL 1169
                  5699*******************************************8 PP

  == domain 8  score: 5.3 bits;  conditional E-value: 0.013
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLl 36  
                  Ll++g a+  ++d++  t++ +A+++ + ++v+lLl
  EEA22878.1 1184 LLKKG-AASHAQDKYERTAIFWAVENSHEEMVKLLL 1218
                  78899.88889************************9 PP

  == domain 9  score: 12.6 bits;  conditional E-value: 6.5e-05
       Ank_5   20 LhvAakygaadvvrlLlargadlnltdsrGltal 53  
                  L  Aak+g+ d ++lL+++gad+ ++  +G+t+l
  EEA22878.1 1326 LLRAAKQGNGDSAKLLVDEGADIHTRSVYGETPL 1359
                  667******************************8 PP

  == domain 10  score: 30.3 bits;  conditional E-value: 1.9e-10
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltal 53  
                  L+++g ad+ ++  +g+tpL +Aa++g a +v++L++rgad+  +d+ Glt+l
  EEA22878.1 1341 LVDEG-ADIHTRSVYGETPLWWAARNGDAMLVEFLYNRGADIESKDKFGLTPL 1392
                  78999.**********************************************8 PP

  == domain 11  score: 27.7 bits;  conditional E-value: 1.2e-09
       Ank_5    7 advnrldgggntpLhvAakygaadvvrlLlargadlnltdsrGltald 54  
                  ad+  +d++g tpL +A+++++++vv+lL+  ga++++ d++G+t+l 
  EEA22878.1 1379 ADIESKDKFGLTPLSWAVENRHWSVVELLVGWGANIRAPDKSGQTPLS 1426
                  889999****************************************96 PP

>> PNP_UDP_1  Phosphorylase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.6   0.4     6e-16   1.2e-12       2     231 ..      16     308 ..      15     316 .. 0.80

  Alignments for each domain:
  == domain 1  score: 47.6 bits;  conditional E-value: 6e-16
                 EEEEESSHHHHHHHHHHEEEEEEEEEE...TTEEEEEEEETTEEEEEEE--...SSHHHHHHHHHHHHHHHC--SEEEEEEEEEES...STTT-TT-EE CS
   PNP_UDP_1   2 iaiivgspgevellaespleetpfgre..grgfkfvtGtlkgkpvvivstG...iGkpnaavvaeirllkefgvkaiiriGtaGgl...npdlkvGDvv 92 
                 +a i++ p e+++  +   e +p  ++  g   + v G+++ ++v+i++      G+++aa va ++ l   g++  +++G+aGg+   ++d+++GDvv
  EEA22878.1  16 VAWICALPIEMAAAEAMLDERHPALPTiaGDDNTHVAGRVGSHNVIIACLPagvYGTTSAANVASQMRLTFPGIRFGLMVGIAGGVptaDHDIRLGDVV 114
                 677999998888888888888999999888889999***********99998977******7777777775578888********************** PP

                 EEEEEEESSSCCGCCTHHCC............................................TCCCCTTSSEE--HHHHHHHHH............C CS
   PNP_UDP_1  93 ipddainfdgrsplygpkee............................................gqyfpdsydapadpelrallke............a 135
                 + +   +f g  ++ + k                                              + +++++ ++++d++  +ll+e             
  EEA22878.1 115 VGKPTRDFGGVIQYDYGKAVsgghlertgvlnkpptmlltavtalqsahianksripdlisdlaERHPRMKGKFTYDSRREDLLFEaqydhtdraptcD 213
                 **9965555555544444445566669************************************988888888888888888888887776666643330 PP

                 HHTTT................TTEEEEEEEEESESS-CHHHHHHHHHHTC-CEEESSHHHHHHHHHHTT--EEEEEEEEETTTBETTCTCH.HCCCHHH CS
   PNP_UDP_1 136 aealg................ikvhrGvvatadgfyaeteaelrllrrlgadaveMEtaavaqlArelgipfaairvvsdlaaggadaeatheeveefa 218
                     g                + +h+G++a+++++  + + +++l r++g+ + eME+a ++        p+++ir++ d+a+ +  ++         +
  EEA22878.1 214 ----GcdrhqlvtraprdcndPVIHYGLIASGNQVMKDGRTRDQLAREMGILCFEMEAAGLVDT-----FPCLVIRGICDYADSHKNKQ--------WQ 295
                 ....25555666666677788**************************************99986.....9**********777744433........33 PP

                 HHHHHHHHHHHHH CS
   PNP_UDP_1 219 qeaaknaaallla 231
                 + aa +aa  +++
  EEA22878.1 296 EYAAATAAGYAKE 308
                 3333444444333 PP

>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.0   0.0   1.8e-09   3.6e-06       3     128 ..     404     553 ..     402     568 .. 0.77

  Alignments for each domain:
  == domain 1  score: 27.0 bits;  conditional E-value: 1.8e-09
                 EEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-.......-HCHHHCCCCTS--SSS-C........................CH CS
       NACHT   3 vilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgna....rsladllfsqlpepaapvse........................vw 73 
                 ++  G+ GsGKTt +   ++a++ +  ++ a +  Ff + ++++++ n      sl+++l++ l++++++ +                         v+
  EEA22878.1 404 LWCSGKIGSGKTTIATAAIDAAKYRLSKHSA-STAFFYCESDRPDELNGlyilSSLIKQLCEYLLAKNRRCPDnvaaalnlffgkkrvipdcedlkeVF 501
                 7899*************99999999999986.7888877777777766665655555555555555555544489989999999999999999999988 PP

                 HHHCCSCCCEEEEEE-STT-SS-TCH.........HHHHHCTTTT.T--EEEEEEE CS
       NACHT  74 avllelperlLlilDglDelvtdlgqkekqpvrtlLselirkkll.peasllltvr 128
                   l  l   ++ i+Dg+D l  d ++     + + +++l+ ++ + pe+++l+ +r
  EEA22878.1 502 FQLFHLIPDTVYIIDGFDALNPDQSK----DLFEFFRSLFCGSGCpPESRMLVFSR 553
                 888888888889*********96666....88888999887775515666666665 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   1.3e-05     0.026      27     158 ..     404     533 ..     396     550 .. 0.60

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.3e-05
      AAA_16  27 vllsGesGvGKsslvrellralekd....ggiflrgkcdqlesaipy.....salaqalareellrqlldeaesaeleawrekleealaavpelagaea 116
                 + +sG  G+GK+++++++ +a++ +        +++ +  +es++p      ++l +++ + +l++ ll++      ++ ++   +al+      g+++
  EEA22878.1 404 LWCSGKIGSGKTTIATAAIDAAKYRlskhS---ASTAFFYCESDRPDelnglYILSSLI-K-QLCEYLLAK-----NRRCPDNVAAALN---LFFGKKR 489
                 789************999998888876542...44444444444443112213333333.4.555555555.....3333333333333...2223333 PP

      AAA_16 117 .....srllellkrllallsrderplvlvlDdlqwade.aslqllaaL 158
                      ++l e++ +l+ l++     +v ++D ++ + + +s +l++++
  EEA22878.1 490 vipdcEDLKEVFFQLFHLIPD----TVYIIDGFDALNPdQSKDLFEFF 533
                 555667788887777777777....89999999965552555555554 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.0   3.4e-05     0.068      10     116 ..     406     537 ..     402     543 .. 0.66

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 3.4e-05
      AAA_22  10 vtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsst....sskdllrellralglelka.........................erlsseell 79 
                 + G  G+GKTt +    + ++  +   +++++++f+++ s+     +   +l+ l ++l     +                            + e+l 
  EEA22878.1 406 CSGKIGSGKTTIATAAIDAAK--YRLSKHSASTAFFYCESDRpdelNGLYILSSLIKQLC----EyllaknrrcpdnvaaalnlffgkkrVIPDCEDLK 498
                 899***************983..5555599999999999999664433333333333333....33444655566666655555555444223334444 PP

      AAA_22  80 ealeqalrarav..........ielliiDEaqhlr...seealeeLrsll 116
                                         + iiD ++ l+   s++++e++rsl+
  EEA22878.1 499 -----------EvffqlfhlipDTVYIIDGFDALNpdqSKDLFEFFRSLF 537
                 ...........1444455555559**********9886699999999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1440 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       384  (0.0214178); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.85u 0.28s 00:00:01.12 Elapsed: 00:00:00.45
# Mc/sec: 9696.32
//
Query:       EEA22879.1  [L=823]
Description: beta-D-glucoside glucohydrolase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.4e-55  186.3   0.1    1.3e-54  185.3   0.1    1.5  1  Glyco_hydro_3_C  Glycosyl hydrolase family 3 C-terminal domai
    2.7e-40  138.7   0.0    4.2e-40  138.1   0.0    1.2  1  Glyco_hydro_3    Glycosyl hydrolase family 3 N terminal domai
    7.7e-27   93.2   0.0    1.5e-26   92.3   0.0    1.5  1  Fn3-like         Fibronectin type III-like domain
    8.3e-12   44.9  17.2    8.3e-12   44.9  17.2    3.2  3  CBM_1            Fungal cellulose binding domain
  ------ inclusion threshold ------
       0.15   12.3   4.4       0.36   11.1   4.4    1.6  1  Toxin_7          Toxin 7


Domain annotation for each model (and alignments):
>> Glyco_hydro_3_C  Glycosyl hydrolase family 3 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  185.3   0.1   3.6e-58   1.3e-54       1     204 []     354     599 ..     354     599 .. 0.91

  Alignments for each domain:
  == domain 1  score: 185.3 bits;  conditional E-value: 3.6e-58
                      -EEEEEGSS--S-S-STEEEEEESGGGS................SS-SS-BSSS----S---HHHHHHHHHHH...........-HHHHHHHHH CS
                      xxxxxxxxxxxxxxxxxxxxxxxxxxxx................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.........xxxxxxxxxxx RF
  Glyco_hydro_3_C   1 iVLLkNennlLPLkkklkkiaviGpnad................etlklGggsgtvtvsylvsplegirerles.........eegideaveaa 69 
                      iVLLkN n++LPL +k ++ia+iG +a+                +tl +G+gsgt++++yl++pl++i+ +++s         ++++++ ++aa
       EEA22879.1 354 IVLLKNTNGTLPL-NKPTSIAIIGTDAQtnpsgpnactdhgcdtGTLAMGWGSGTCQFPYLTDPLTAIKSQAASdgttittsiSDDSSAGASAA 446
                      8************.5556******************************************************889********889999999** PP

                      HHTSEEEEEEEES...SB-TT........SCSGHHSSTTHHHHHHHHHHTTSSEEEEEEESSGG--TTT.GTTTEEEEEE-S--GCCHHHHHHH CS
                      xxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxx RF
  Glyco_hydro_3_C  70 keaDvavvvvgedpeiegEgv........Drtdlalpeaqdelikavaaanknvvvvlqsggpvavepw.keenvkAilaawlpGqegGtaiad 154
                      ++a++a+v++++d   +gEg+        Dr++l+  ++ ++l++avaa+nk+++vv++s gpv +e + +++nv A+++a lpGqe+G a+ad
       EEA22879.1 447 QSAEYAIVFINSD---SGEGYitvegvagDRNNLDPWHSGNALVQAVAAVNKKTIVVIHSVGPVILETIlAQPNVVAVVWAGLPGQESGSALAD 537
                      *************...99999999999********99*****************************999*999********************* PP

                      HHTTSS---B--SS-EESSSGGG.........................S.-----S...ETTTT-BCH CS
                      xxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxx........xx.xxxxxx...xxxxxxxxx RF
  Glyco_hydro_3_C 155 vLfGdvnPsGkLpvtfpksledlpd......dyyeekdt........yk.fegtpl...YpeGlglsY 204
                      +L+G+  PsGkL++t++k+++d+ +      d      +        y+ f+++++   Y++G+glsY
       EEA22879.1 538 ILYGRTAPSGKLTYTIAKQASDYGTavvsgnD------NypeglfvdYRhFDKSNIqprYEFGYGLSY 599
                      ***********************442332222......122445666666666666677********9 PP

>> Glyco_hydro_3  Glycosyl hydrolase family 3 N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.1   0.0   1.2e-43   4.2e-40      64     318 ..      66     310 ..      58     311 .. 0.90

  Alignments for each domain:
  == domain 1  score: 138.1 bits;  conditional E-value: 1.2e-43
                    ..S--EEEE---BTTB---SSS.---S-HHHHHHHT-HHHHHHHHHHHHHHHHHHT--EE---B--.---STTSSSGGGSS-SSHHHHHHHHHHHH CS
  Glyco_hydro_3  64 lgiPlllavDqegGlvqrlgeg.tlfPsalalaatssldlikelgriiakelralgididfaPvvd.vnrdprngigvrsFsedpelvaalaaamv 157
                    +  P l+  D   G++    +  t fP+ +  + t++++li++ g +i++e   lg++++++Pv+  +++  + g+g ++F  dp+l +    +++
     EEA22879.1  66 ISFPSLCIQDSPLGVR--YANPvTAFPAGTNAGMTWDRTLINQRGAAIGAESKGLGVHVQLGPVAGpLGKIAQGGRGWEGFATDPYLSGVAMIETI 159
                    5568889999999998..55666******************************************7366666666********************* PP

                    HHHHHTT-EEEEEEETTGTT-SSETTTSEEB----HHHHHHTTHHHHHHHHHTT-SEEEE---B-TTT---BGGG-HHHHIIIIIIIS---SEEEE CS
  Glyco_hydro_3 158 kGlqgagvaatvKHFpghGdgavdshkelptvdhseeelrevdlvpfqaaieagvdsVMtaHvqfpaldgtpatgskklltdvLRkelGFdGvvvs 253
                    +G+q+ g  a++KH++g   ++++ ++e    +++ + l+e +l pf  a++a+v sVM +   +++++gt    +++ +t +L++elGF G +++
     EEA22879.1 160 TGMQSSGTQACAKHYIG---NEQELNRESMSANIDDRTLHELYLWPFADAVRANVASVMCS---YNQINGTFSCEDEESMTRILKTELGFPGYIMT 249
                    *****************...5****************************************...******************************** PP

                    S-TTSHHHHCCS-HHHHHHHHHHHT-SBEES-S---SG......HHHHHHHHHTTSS-HHHHHHHHHHHHH CS
  Glyco_hydro_3 254 DalamkeiadrggkeeavvlaLkAGvDilLvpeertse......ikalkkavkeGeltearidesvrrvlr 318
                    D+            ++  + + ++G+D+ +  ++++ +       ++l+ka+++G+++++r+d+ v rvl 
     EEA22879.1 250 DWN----------AQHTTANSANSGLDMTMPGSDYSNTpssvfwGQNLAKAISSGQVAQSRLDDMVIRVLA 310
                    **9..........33344455678888888887777667777778************************85 PP

>> Fn3-like  Fibronectin type III-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.3   0.0   4.2e-30   1.5e-26       1      71 []     651     721 ..     651     721 .. 0.99

  Alignments for each domain:
  == domain 1  score: 92.3 bits;  conditional E-value: 4.2e-30
                 EEEEEEEEESS-STTSBS-EEEEEEEEEE-TT-EEEEEEEEECGGG-EEETTTTEEE--SCEEEEEEESSS CS
    Fn3-like   1 evvqlYvsdpessverpvkeLkgFekveLapGesktvtftldrkdlsvwdeekqkwvvepGeytvlvgtss 71 
                 ev+qlY+  p+s  + p+k+L+gFek +La+G+s t+tf+l+r+dls+wd+ +qkwvv++G +t++vg+ss
  EEA22879.1 651 EVAQLYIGLPSSAPSSPPKQLRGFEKLSLAAGASGTATFDLTRRDLSYWDVSQQKWVVPSGAFTLYVGASS 721
                 8********************************************************************98 PP

>> CBM_1  Fungal cellulose binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   1.1       1.1   3.9e+03       6      12 ..     137     143 ..     137     146 .. 0.90
   2 ?   -3.2   0.9       2.4   8.5e+03      11      19 ..     384     392 ..     384     396 .. 0.76
   3 !   44.9  17.2   2.3e-15   8.3e-12       1      29 []     790     818 ..     790     818 .. 0.98

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 1.1
       CBM_1   6 GGigWtG 12 
                 GG gW G
  EEA22879.1 137 GGRGWEG 143
                 9****99 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.4
       CBM_1  11 tGpTtCvsg 19 
                 +Gp +C++ 
  EEA22879.1 384 SGPNACTDH 392
                 69****985 PP

  == domain 3  score: 44.9 bits;  conditional E-value: 2.3e-15
       CBM_1   1 lwgQCGGigWtGpTtCvsgatCtyqNeyY 29 
                 ++gQCGG+gWtGpTtC sg+tC+++N++Y
  EEA22879.1 790 AYGQCGGQGWTGPTTCPSGWTCKVSNQWY 818
                 5**************************** PP

>> Toxin_7  Toxin 7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   4.4    0.0001      0.36      12      34 .]     799     822 ..     794     822 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.0001
     Toxin_7  12 lagPr.CCsGlkCkelsipdsiCl 34 
                 + gP  C sG +Ck  +++ s Cl
  EEA22879.1 799 WTGPTtCPSGWTCKVSNQWYSQCL 822
                 889963779**************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (823 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1023  (0.0570584); expected 358.6 (0.02)
Passed bias filter:                      499  (0.027832); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.79u 0.29s 00:00:01.08 Elapsed: 00:00:00.45
# Mc/sec: 5483.46
//
Query:       EEA22880.1  [L=433]
Description: mitochondrial import receptor subunit (Tom37), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.8e-40  137.5   0.2    5.1e-40  136.7   0.2    1.4  1  Tom37     Outer mitochondrial membrane transport complex prot
    3.6e-13   49.1   0.3    2.6e-11   43.1   0.0    3.4  3  GST_C_6   Glutathione S-transferase, C-terminal domain
    5.2e-05   23.9   0.0    0.00011   22.8   0.0    1.6  1  GST_N_4   Glutathione S-transferase N-terminal domain
    0.00021   21.3   0.0     0.0012   18.8   0.0    2.3  2  GST_C_2   Glutathione S-transferase, C-terminal domain


Domain annotation for each model (and alignments):
>> Tom37  Outer mitochondrial membrane transport complex protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  136.7   0.2   1.1e-43   5.1e-40       1     125 []      21     146 ..      21     146 .. 0.98

  Alignments for each domain:
  == domain 1  score: 136.7 bits;  conditional E-value: 1.1e-43
       Tom37   1 Claviaylkllal..apfevvessnpslsptgeLPaLkdgegtwisgfdnIveylrkks.eesdldaslsakekadatAlisllesklaplllyslyvn 96 
                 Cla+iayl   ++  +++ +v+ss+ps+spt+eLPaLkdg+ tw+s+f+nIv+y+r++s ee+dlda+ +  +kad tA++++les+ + ll++slyv+
  EEA22880.1  21 CLATIAYLA-KTVpkDKWVLVASSDPSVSPTNELPALKDGQ-TWVSKFRNIVDYVRQYSsEEWDLDADWDGLDKADITAFSAFLESNGQFLLDLSLYVS 117
                 *********.6666*************************99.**************999**************************************** PP

       Tom37  97 senyekvTrpayskllpfPlnyilplklr 125
                 s+ny ++T+pay+++l +P ++ilp+klr
  EEA22880.1 118 SQNYYAATSPAYGSILTWPNQWILPPKLR 146
                 **************************987 PP

>> GST_C_6  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0     0.081   3.7e+02      47      62 ..      59      74 ..      48      76 .. 0.80
   2 ?   -0.1   0.1      0.18     8e+02       2      19 ..      92     110 ..      92     115 .. 0.76
   3 !   43.1   0.0   5.9e-15   2.6e-11       4      64 .]     219     282 ..     216     282 .. 0.92

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.081
     GST_C_6 47 lrellkeypNLvayce 62
                 ++ ++++ N+v+y++
  EEA22880.1 59 GQTWVSKFRNIVDYVR 74
                578899********97 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.18
     GST_C_6   2 kkdleaLselLg.dkkyFf 19 
                 k+d++a s +L+ + ++++
  EEA22880.1  92 KADITAFSAFLEsNGQFLL 110
                 5799*******52667776 PP

  == domain 3  score: 43.1 bits;  conditional E-value: 5.9e-15
     GST_C_6   4 dleaLselLgdkkyFfG..dkPtslDAlvFGhlaqilytplespelrellk.eypNLvayceri 64 
                  +e L +lLg+kky++   ++P+slD+lv G+l + l+  ++ ++lre l+ ++p L +y+er+
  EEA22880.1 219 LFEPLEQLLGSKKYLLAdgQQPSSLDVLVLGYLSLALFPEVPYTWLRESLRtKTPRLAKYVERM 282
                 57889***********95457***************99988888*******************9 PP

>> GST_N_4  Glutathione S-transferase N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8   0.0   2.6e-08   0.00011       2      99 .]      20     120 ..      19     120 .. 0.86

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 2.6e-08
     GST_N_4   2 fclkletyLrmagip..yelepssne.mhaspkgklPfielngelliadsefiieflkekg...vdldaelseeqkadaralkalveeklynallyerw 94 
                 +cl+  +yL  +  +  + l+ ss++ +  sp+++lP ++ +++  ++ + +i++++++      dlda+ +  +kad  a+ a +e++  ++l   ++
  EEA22880.1  20 QCLATIAYLAKTVPKdkWVLVASSDPsV--SPTNELPALKDGQT-WVSKFRNIVDYVRQYSseeWDLDADWDGLDKADITAFSAFLESNGQFLLDLSLY 115
                 6777777776554445599999999977..***********877.*************9998778888*********************9999999999 PP

     GST_N_4  95 ldpen 99 
                 ++++n
  EEA22880.1 116 VSSQN 120
                 88776 PP

>> GST_C_2  Glutathione S-transferase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.0      0.68   3.1e+03      53      68 ..      59      74 ..      45      75 .. 0.83
   2 !   18.8   0.0   2.8e-07    0.0012      12      69 .]     217     281 ..     195     281 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.68
                S----TT-HHHHHHHH CS
     GST_C_2 53 gfdireaypnlraWle 68
                g+++ +++ n++++++
  EEA22880.1 59 GQTWVSKFRNIVDYVR 74
                4589999999999986 PP

  == domain 2  score: 18.8 bits;  conditional E-value: 2.8e-07
                 CHCHHHCTTT---SS.CTTC..S--HHHHHHHHHHHHHHHHHHS-.....---TT-HHHHHHHHH CS
     GST_C_2  12 daaldaleahLadspflfGd..qptlaDialapflvrlraagpgf.....direaypnlraWler 69 
                  + ++ le++L+ + +l+ d  qp+  D+ + + l  + ++  +       +r + p+l++++er
  EEA22880.1 217 AELFEPLEQLLGSKKYLLADgqQPSSLDVLVLGYLSLALFPEVPYtwlreSLRTKTPRLAKYVER 281
                 678999*********7777777****************9996666355666669*********98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (433 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       344  (0.0191868); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.52u 0.24s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 3095.03
//
Query:       EEA22881.1  [L=359]
Description: plasma membrane low affinity zinc ion transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.2e-67  226.4   5.7    5.9e-67  226.3   5.7    1.0  1  Zip       ZIP Zinc transporter


Domain annotation for each model (and alignments):
>> Zip  ZIP Zinc transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  226.3   5.7   3.3e-71   5.9e-67       2     332 ..      15     355 ..      14     356 .. 0.84

  Alignments for each domain:
  == domain 1  score: 226.3 bits;  conditional E-value: 3.3e-71
         Zip   2 llkilaiiaililsllgllgpllvpkiskl.lsklllslllafavGvllgtaflhLlPealealeesqleeehth.plagllvllGflllllveklltm 98 
                 +l+i +i++il+ sl+g ++p+l ++   +  ++++++++++f++Gv+++taf+hLl++a eal +++l + +t+  +++++vl+ ++++++ve ++  
  EEA22881.1  15 GLRISSIFVILAGSLFGAVFPVLAKRLGGDgIPSWAFFIAKYFGSGVIIATAFIHLLAPAEEALTNPCLTGPITEySWVEGIVLMTIVVMFFVELMVMR 113
                 689************************999*****************************************96667******************98754 PP

         Zip  99 ivek........ksshkektpkkasssssesaakksvsndkveeseekedhvaeadtdadskeelrngkqeksesekeqaseeedkeklaslkvraiil 189
                    +        +s+ +e+ +  a+s+s  +++ ++ ++d +++++   +  +e+++ + +++  + +    ++ e+  +s   + e++a++ ++++il
  EEA22881.1 114 N--SfpdghghgHSHDEEDHERGAHSHSHSQSTLRTPDADAITTESPICNSPKEHEHVPGNDHLSHTRDH--HDLESD-KSPLISAEDYAAQLTAVFIL 207
                 2..2245899864444444444444444445555666666666666555555555555544443333222..222222.2245679************* PP

         Zip 190 llglilHsfidGLAlGvssssstgislfiAvllHelpeelglgaiLlkaglsrkkav...llnllfaltaplGiliGilvrs..isessgaeivsgill 283
                 ++g+i+Hs+++GL l+  +s + +++l++++++H+ +e+lglg++L+   ++++k +   ll + +a+++p++i+iG++vr+   + +++ +iv+g+++
  EEA22881.1 208 EFGIIFHSVFIGLTLA--VSGQDFVTLYVVLVFHQTFEGLGLGSRLATLPWPKSKRFtpyLLGIGYAISTPIAIAIGLGVRNtyPPDGRTTLIVNGVFD 304
                 ****************..9*************************************9999***********************99999*********** PP

         Zip 284 alsaGtflYvalvellphEllnek..gssslkqsllqllglllGfalmlll 332
                 ++saG+++Y+alvel++hE++ +   +  +l++ l ++++++lG+alm+ll
  EEA22881.1 305 SISAGILIYTALVELMAHEFMFSTsmRRARLSTVLWAFFLICLGAALMALL 355
                 ************************8877899999***************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (359 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       625  (0.0348597); expected 358.6 (0.02)
Passed bias filter:                      295  (0.0164538); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 2361.89
//
Query:       EEA22882.1  [L=518]
Description: metabolite transport protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-52  178.4  27.8    1.5e-27   96.6   7.7    2.0  2  Sugar_tr  Sugar (and other) transporter
    1.3e-16   60.5  36.9    9.7e-10   37.9  12.6    2.1  2  MFS_1     Major Facilitator Superfamily
     0.0055   15.3  24.0       0.25    9.8   0.8    3.8  4  MFS_2     MFS/sugar transport protein
  ------ inclusion threshold ------
       0.48    8.8  14.3       0.12   10.7   5.2    2.6  2  TRI12     Fungal trichothecene efflux pump (TRI12)


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.0  12.2   1.3e-28     6e-25       5     195 ..      65     260 ..      62     271 .. 0.87
   2 !   96.6   7.7   3.2e-31   1.5e-27     240     452 .]     279     480 ..     266     480 .. 0.95

  Alignments for each domain:
  == domain 1  score: 88.0 bits;  conditional E-value: 1.3e-28
                 HHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTT...S CS
    Sugar_tr   5 aalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgk...n 100
                 +  +g+    d +  + +++ + ++k+++ ++++++       s+ + +++lvG+iiG l++gl  d++GRk +++i++++ v+g++l  a++g+    
  EEA22882.1  65 ILAAGFALISDGYQNNLMTMTNVVLKREYPDQYTATV------STRVSNALLVGEIIGMLVIGLTCDYLGRKRAIVITTMMIVVGGILATASHGNtiaG 157
                 4556688888888888888888877888777777644......48************************************************99999* PP

                 S-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCC...HH.HHHHHHHHHHHHHHHHHHHHHHHH.HTSS-...TTHHHHHHHCCHHHHHHHHHHGGGS CS
    Sugar_tr 101 svevlivgRvlvGigvGlasvlvPmyisEiApkkl...Rg.alvslyqlaitfGilvaaifglgl.nktsn...adgwrillglqlvpallllilllfl 191
                 ++++++v+R  +G+g+G+++  +++ +sE A ++    Rg +++ +++l ++fG  +a i+ l++   +++   ++ wr+ +g+ ++++l ++++++ +
  EEA22882.1 158 MFWMMTVARGTIGFGAGGEYPASSVAASEAANEHAlkrRGpTFILVTNLPLSFGGPFAVIIFLIVfLACQQshySTVWRVCFGIGCIWPLSVFYFRIRM 256
                 *******************************665422244478999*****************99888888999*******************999876 PP

                 ---H CS
    Sugar_tr 192 PESP 195
                  +S 
  EEA22882.1 257 LNSV 260
                 6665 PP

  == domain 2  score: 96.6 bits;  conditional E-value: 3.2e-31
                 ..HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THHHHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..H CS
    Sugar_tr 240 aswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsksllvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgiva 338
                  +wk+l+++++       +++++++++ +Gi++ +++s+ + +   l +  ++ +++g++    +f++++l dr+GR+++++lG++g++++ +i+g + 
  EEA22882.1 279 YYWKTLIGTCG------AWFLYDFVTFPNGIFSATIISSIVPDGSILRTA-QWQLLLGTLSLPGVFIGAWLCDRIGRKQTMMLGFSGYLVFGLIIG-CS 369
                 57999999988......99*******************999999999999.********************************************9.99 PP

                 HHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS CS
    Sugar_tr 339 lllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRskalaiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffv 437
                 +   +k   +  +++vf+ l+    +lg+g ++ +++sE + ++vR++++ i++av      + ++ f+ i  ++g+ ++f+v a++ v++ii++++fv
  EEA22882.1 370 FDKITK---IVPLFVVFYGLMQSSGNLGPGDMLGLISSEAYATAVRGTCYGISAAVGKAGAAIGTQAFKPIEINLGKRWTFIVAAICGVVGIIVTYLFV 465
                 999999...6***************************************************************************************** PP

                 --STT--CCCCGGGT CS
    Sugar_tr 438 petkgrtleeieelf 452
                 p   g+ l+e +e f
  EEA22882.1 466 PNLTGENLKENDERF 480
                 *********988765 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.7  19.0   5.5e-10   2.5e-06      37     223 ..     105     303 ..      64     315 .. 0.64
   2 !   37.9  12.6   2.2e-13   9.7e-10      33     185 ..     321     478 ..     296     509 .. 0.75

  Alignments for each domain:
  == domain 1  score: 26.7 bits;  conditional E-value: 5.5e-10
       MFS_1  37 lltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.....ss.lwlllvlrvlqGlgagalfpagaaliadwfpkeergraigllsag 129
                 +  +  +g ++++l++G   d +Gr+r ++++  + ++g++l++ +     ++ +w++ v+r   G+gag+ +pa+ +++++ +++    r    + + 
  EEA22882.1 105 VSNALLVGEIIGMLVIGLTCDYLGRKRAIVITTMMIVVGGILATAShgntiAGmFWMMTVARGTIGFGAGGEYPASSVAASEAANEHALKRRGPTFILV 203
                 555678899******************77777777777746666333444433477******************************9999999999999 PP

       MFS_1 130 fslGailgpllgg......llasslg......Wravfyilaivsllafvlfllll....peepperkrkspkeeekgtgpaplvp..awkallkdpvlw 210
                 ++l   +g +++       +            ++ v+ ++ ++++++ +   +++    + + +  +r + k++    +p +lv    wk l      w
  EEA22882.1 204 TNLPLSFGGPFAViiflivF-----LacqqshYSTVWRVCFGIGCIWPLS--VFYfrirMLNSVLYRRGAIKKR----VPYSLVLryYWKTLIGTCGAW 291
                 99999999888884433333.....1555556666666666666666552..3330111333333333333333....444444455555555555555 PP

       MFS_1 211 illialllfffgf 223
                  +l+ +++f  g+
  EEA22882.1 292 -FLYDFVTFPNGI 303
                 .555555554444 PP

  == domain 2  score: 37.9 bits;  conditional E-value: 2.2e-13
       MFS_1  33 eigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll..fasslw.lllvlrvlqGlgagalfpagaaliadwfpkeergraigllsa 128
                 ++++ l l +l ++ +++++++l dr+Gr+ +++lg+ ++++++l++   f   ++ ++ ++ v+ Gl++++++ + + ++  ++++   + a+++ ++
  EEA22882.1 321 TAQWQLLLGTL-SLPGVFIGAWLCDRIGRKQTMMLGFSGYLVFGLIIGcsF-DKITkIVPLFVVFYGLMQSSGNLGPGDMLGLISSE---AYATAVRGT 414
                 46665555444.899****************************77777577.88888999999999999999999999999998888...788888888 PP

       MFS_1 129 gfslGailgpllggllasslg.......Wravfyilaivsllafvlfllllpeepperkrkspk 185
                 +++++a++g + +++ ++++         r++f+++ai +++++++ +l++p    e+ +++++
  EEA22882.1 415 CYGISAAVGKAGAAIGTQAFKpieinlgKRWTFIVAAICGVVGIIVTYLFVPNLTGENLKENDE 478
                 8888888886666666666667777777***************999777766555555555444 PP

>> MFS_2  MFS/sugar transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.7   7.9     0.001       4.6     265     325 ..     106     166 ..      96     222 .. 0.80
   2 ?   -0.8   0.4     0.094   4.2e+02      76     180 ..     213     244 ..     203     266 .. 0.50
   3 !    9.8   0.8   5.7e-05      0.25     264     320 ..     325     382 ..     319     393 .. 0.75
   4 !    9.5   0.2   7.1e-05      0.32     261     311 ..     416     466 ..     407     476 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.7 bits;  conditional E-value: 0.001
       MFS_2 265 llvvtisallgiplwqplakrlgkkntyllgalltivllvlvlllqpsnlllflvllviag 325
                 + ++ ++ ++g++++   +  lg+k+++++ +++ +v+++l+ + + + ++ ++ ++++a 
  EEA22882.1 106 SNALLVGEIIGMLVIGLTCDYLGRKRAIVITTMMIVVGGILATASHGNTIAGMFWMMTVAR 166
                 557889***************************************8888887777777653 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.094
       MFS_2  76 iilavsiillftppelsqsakfiwllvtyillrilytlfeipyvslvpvltkdydeRtsltsvrsflsvlggvlaailafllvlilgglkserkgylif 174
                 +++++ ++ +f++ +                                                                          ++  + +++ 
  EEA22882.1 213 PFAVIIFLIVFLACQ-------------------------------------------------------------------------QSHYSTVWRVC 238
                 333333333333333.........................................................................24444444444 PP

       MFS_2 175 aliial 180
                   i+++
  EEA22882.1 239 FGIGCI 244
                 444433 PP

  == domain 3  score: 9.8 bits;  conditional E-value: 5.7e-05
       MFS_2 264 fllvvtisallgiplwqplakrlgkkntyllgalltivllvlvlll..qpsnlllflvl 320
                 +ll + +++l g+++ ++l+ r+g+k+t++lg++ ++v+++++     + +++++++v+
  EEA22882.1 325 QLL-LGTLSLPGVFIGAWLCDRIGRKQTMMLGFSGYLVFGLIIGCSfdKITKIVPLFVV 382
                 444.445668899999****************999999876544333378888877776 PP

  == domain 4  score: 9.5 bits;  conditional E-value: 7.1e-05
       MFS_2 261 asvfllvvtisallgiplwqplakrlgkkntyllgalltivllvlvlllqp 311
                 + ++++v  ++a++g+  ++p+   lgk+ t++++a+  +v+ ++++l+ p
  EEA22882.1 416 YGISAAVGKAGAAIGTQAFKPIEINLGKRWTFIVAAICGVVGIIVTYLFVP 466
                 56777888999************************************9954 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   5.2   2.7e-05      0.12      83     149 ..     105     170 ..      82     174 .. 0.89
   2 ?    2.9   1.5    0.0065        29      97     220 ..     338     466 ..     304     491 .. 0.59

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 2.7e-05
       TRI12  83 fstlwttgqavsilvmgrltdrfgrrpfvilthilglvgaivgctatkfntllaamtllgvaagpag 149
                 +s    +g+ + +lv+g   d +gr+  +++t ++ +vg i+ +ta++ nt+   + ++ va g  g
  EEA22882.1 105 VSNALLVGEIIGMLVIGLTCDYLGRKRAIVITTMMIVVGGIL-ATASHGNTIAGMFWMMTVARGTIG 170
                 566677899****************99999999999****98.58999****99999*****99877 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.0065
       TRI12  97 vmgrltdrfgrrpfvilthilglv.gaivgctatkfntllaamt.llgvaagpagasplfvgelmsnk...tkflglli.vsipv.vvtsglspylgqr 188
                 +   l dr+gr+  ++l     lv g i+gc+ +k+  ++  +  + g+        p  +  l+s     t + g    +s+ v  + ++++    + 
  EEA22882.1 338 IGAWLCDRIGRKQTMMLGFSGYLVfGLIIGCSFDKITKIVPLFVvFYGLMQSSGNLGPGDMLGLISSEayaTAVRGTCYgISAAVgKAGAAIGTQAFKP 436
                 445689999999998888776665589999999888877655431345544333333433333333331113334433212222202233344444556 PP

       TRI12 189 laiqgswrwifyiyiitsaiavllivvwyypp 220
                 + i+   rw f +  i   +   +iv + + p
  EEA22882.1 437 IEINLGKRWTFIVAAICGVVG--IIVTYLFVP 466
                 777777888877666655433..344444555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (518 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       871  (0.0485805); expected 358.6 (0.02)
Passed bias filter:                      469  (0.0261587); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.65u 0.27s 00:00:00.92 Elapsed: 00:00:00.45
# Mc/sec: 3427.90
//
Query:       EEA22883.1  [L=442]
Description: lipase 8 precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.9e-54  184.3   0.6    4.2e-54  183.8   0.6    1.2  1  LIP       Secretory lipase


Domain annotation for each model (and alignments):
>> LIP  Secretory lipase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  183.8   0.6   2.3e-58   4.2e-54       8     281 ..     129     416 ..     123     420 .. 0.85

  Alignments for each domain:
  == domain 1  score: 183.8 bits;  conditional E-value: 2.3e-58
         LIP   8 stvatqaelll..ivplLkeGyyVvvpDyeGpkstftvgrqsgkavLdsiraalksekvtgiksda...kvalwGYSgGslAsawAaelqpeYAPelel 101
                  t++t+++ ++  i+++L +G+yV+v+D+eGp++tf+vg  +g+avLd++ra+ ks ++  ++s +   k++lwGYSgGs+As +Aael ++YAPe+e+
  EEA22883.1 129 WTLSTGLNWTFpdITAALLQGWYVSVTDFEGPNATFGVGAAEGHAVLDGLRAVTKSSSSPAVASGVkawKIGLWGYSGGSIASEFAAELRASYAPEMEI 227
                 478888888776699******************************************9988886542228***************************** PP

         LIP 102 vGaalGgfvanltavaeavdgtvfaGlialalnglaneypelkkilkeevneeare..aleklsencladalikyagesyltgdkrafekgsdvlkdet 198
                 +G+a+Gg ++ +tav + v+ t faGli   l g an +p + + l + + +e ++  ++ +  ++ + +++  y   ++++         +d++++  
  EEA22883.1 228 AGVAIGGLPTPITAVSQVVNKTPFAGLIISGLWGYANAFPLVESYLLSRLTDEVKAsgNFTAARSMVIDEIFAVYRYVDVFSY---FIGGEADIFSSTL 323
                 ****************************************9988777766665433117999999998888887877665444...3345689999999 PP

         LIP 199 ikkvlednkl.sksavPqiPvlvyhgvidelipikdakklaknwcdkg.........iaslefaedlssgHlaetlvgapaaltWitdRfsgk 281
                 ++ + + +     + +P +P++vy++  d+l pi+d+++l +++c++g         ++++ + ++ + gH+ae      aa+ ++ +  +gk
  EEA22883.1 324 LHYFWDIQGTmGIHGLPDVPMYVYKAIGDQLAPIQDTDALIDKYCAAGqaaaarkegGVQILYERNTIGGHVAEEGNADTAAVEFLSQAINGK 416
                 9999888887566889*****************************86422222222267899999*********************9999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (442 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       212  (0.0118244); expected 358.6 (0.02)
Passed bias filter:                      176  (0.0098165); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.31s 00:00:00.85 Elapsed: 00:00:00.50
# Mc/sec: 2676.05
//
Query:       EEA22884.1  [L=320]
Description: Protein phosphatase 2C, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.5e-40  138.3   0.0      4e-40  138.1   0.0    1.0  1  PP2C      Protein phosphatase 2C
    1.4e-05   24.8   0.0    0.00036   20.2   0.0    2.8  2  PP2C_2    Protein phosphatase 2C
    0.00013   21.9   0.0      0.091   12.7   0.0    2.2  2  SpoIIE    Stage II sporulation protein E (SpoIIE)


Domain annotation for each model (and alignments):
>> PP2C  Protein phosphatase 2C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  138.1   0.0   6.7e-44     4e-40       3     249 ..      18     297 ..      16     306 .. 0.89

  Alignments for each domain:
  == domain 1  score: 138.1 bits;  conditional E-value: 6.7e-44
                 EEEEEECCCCSSHHEEEECCCCTCTT..CCCCCCEEEEEEEEESSSHHHHHHHHHHHHHHHHHHHCHTTHHHHHHHHHHHHHHHHHHHHH..HHHHCHC CS
        PP2C   3 lgaselqgarksmedahislanless..sgkssvsffavfdghggseaakyarehleeilksqksfeelekleqalrksfladtdeelks..skantep 97 
                  ga ++qg r s ed+h++l +++    ++ ++ ++fa +dghg+ ++++  r++l+++l ++++fe++ ++e a++ksf   +d  l +  +++nt p
  EEA22884.1  18 AGAATAQGGRVSQEDRHVILLPNQFPptKSTDKFALFATYDGHGSADVSEHVRQNLPDLLVKRPEFESG-DYETAIIKSFED-EDGLLLRsvMEDNTGP 114
                 5678899**********98876654466999**************************************.9***********.666666656777779* PP

                 CT-EEEEEEEEEETTE..EEEEEESS-EEEEEETTEEE......EECS---STTSHHHHHHHHHTT--EEE.CCEEETTTBSBSB-EE-GGGTCCCC.. CS
        PP2C  98 sksGstavvalirgtk..lyvAnvGDSravLcrkgnak......keltedHkpsdedEreRIeeaggsvsn.gegrvngsLavsRalGDlelkpket.. 185
                    Gst  ++l++ tk  + ++nvGDS + L+r+++         +lt+ Hkp++++E++RIe+agg v   g +  +g+L++sRalGDl++k+  +  
  EEA22884.1 115 VIAGSTVALCLVNLTKgvMVIGNVGDSHIFLARRDDGSefitrqERLTVEHKPNEPSEKSRIEKAGGAVHIyGGTARLGTLNMSRALGDLQYKNPINsl 213
                 ************************************999*********************************77777899*************8555** PP

                 ...................CCSTSB---EEEEEEE-TTEEEEEEE-.HHHHTTSHHHHHHHHHHHHHHHHTHHHHHHHHHHHHH CS
        PP2C 186 ...................eeqlvsaePdvtsvklteedefliLac.dGlwdvlsdqeavdlvrdelekkkspeevaeelvdea 249
                                    +  + s+e +v +++l+e+  + +L c dG++dv +++ ++  v +    ++ ++++a+ + +  
  EEA22884.1 214 ninggtkkakranasgskvRGNILSNEAYVRTIELDEKSRYALLCCtDGVTDVTDEKALMKEVVSDFVVGRRATDIARMVTKAT 297
                 ******************9888****************666666554*********9999877777777888888888776655 PP

>> PP2C_2  Protein phosphatase 2C
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.2   0.0     6e-08   0.00036      21     186 ..      48     273 ..      41     293 .. 0.67
   2 ?   -2.7   0.0      0.61   3.7e+03      86     105 ..     295     314 ..     281     318 .. 0.71

  Alignments for each domain:
  == domain 1  score: 20.2 bits;  conditional E-value: 6e-08
      PP2C_2  21 dsggsllaVaDGaGSakrSerGariaveavvealaell.eseeee....eeallraleaailadv..lkeeaeaqdaelkdyatTllaav..vtpdeiv 110
                 +++ +l+a  DG+GSa  Se+        v+++l +ll +++e e    e a+++++e    ++   l ++ ++    +   ++T+++++  +t++ +v
  EEA22884.1  48 TDKFALFATYDGHGSADVSEH--------VRQNLPDLLvKRPEFEsgdyETAIIKSFE----DEDglLLRSVMEDNTGPVIAGSTVALCLvnLTKGVMV 134
                 677777788899999988887........66666666655555552333344444444....22233455666667777777778777776889***** PP

      PP2C_2 111 alqiGDGaivvrdrdgevqllgepds..geyanqttfltsedaeeel.................................................... 155
                 ++++GD+ i++++rd     ++ ++    e+  +       ++ e++                                                    
  EEA22884.1 135 IGNVGDSHIFLARRDDGSEFITRQERltVEHKPN-------EPSEKSriekaggavhiyggtarlgtlnmsralgdlqyknpinslninggtkkakran 226
                 *********7766665444443322212222222.......222222222234555666666666666777777777********************** PP

      PP2C_2 156 .................rirrlkledgdalllmTDGlanslrdeerfa 186
                                  r  +l++++  all++TDG++ ++ de++++
  EEA22884.1 227 asgskvrgnilsneayvRTIELDEKSRYALLCCTDGVT-DVTDEKALM 273
                 ***************9988899999999*********7.555555443 PP

  == domain 2  score: -2.7 bits;  conditional E-value: 0.61
      PP2C_2  86 eaqdaelkdyatTllaavvt 105
                 +a ++++++  +T+++a+++
  EEA22884.1 295 KATGEQPQSDNCTCVIAFLD 314
                 44577888888888888765 PP

>> SpoIIE  Stage II sporulation protein E (SpoIIE)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.0   0.0    0.0008       4.8      52     105 ..     109     162 ..      91     183 .. 0.82
   2 !   12.7   0.0   1.5e-05     0.091     116     189 ..     243     310 ..     220     313 .. 0.70

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0008
                 HCTTSTT.TTCEEEEEEEETTTTEEEEEEESSSSEEEEETTSTEEEEE--SS-- CS
      SpoIIE  52 ardleeeerfaTavlavydpstgkleyanaGhpppllvrpdggtklllastglp 105
                 +++++    + T+ l+ +++ +g + + n+G++ ++l r+d+g ++ + ++ l 
  EEA22884.1 109 EDNTGPVIAGSTVALCLVNLTKGVMVIGNVGDSHIFLARRDDGSEFITRQERLT 162
                 4445555678899*****************************999998887665 PP

  == domain 2  score: 12.7 bits;  conditional E-value: 1.5e-05
                 EEEEE--TTE..EEEEESCCCCSSSHHHHHHCCCHHCHHHHCT.....HCCHHHHHHHHHHHHTTSSSSS-EEEEE CS
      SpoIIE 116 taelelepgd..tlllyTDGvtEardsdgelfgkerllallasaegesleelldalveellelgsgeleDDitllv 189
                 ++++el++++   ll++TDGvt+  d++  +  ke   +++     ++++++++ + +++ e   ++++D  t ++
  EEA22884.1 243 VRTIELDEKSryALLCCTDGVTDVTDEKALM--KEVVSDFVVG---RRATDIARMVTKATGE---QPQSDNCTCVI 310
                 45555555552269**********9766666..5555566663...4488888888888887...36777666655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (320 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       434  (0.0242066); expected 358.6 (0.02)
Passed bias filter:                      396  (0.0220871); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 2165.70
//
Query:       EEA22885.1  [L=297]
Description: heme/steroid binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-14   52.4   0.0    6.2e-14   51.9   0.0    1.2  1  Cyt-b5    Cytochrome b5-like Heme/Steroid binding domain


Domain annotation for each model (and alignments):
>> Cyt-b5  Cytochrome b5-like Heme/Steroid binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.9   0.0   3.5e-18   6.2e-14       1      73 [.     207     280 ..     207     281 .. 0.91

  Alignments for each domain:
  == domain 1  score: 51.9 bits;  conditional E-value: 3.5e-18
                 EHHHHTTTECTT..EEEEEETTEEEECTTTCCCSTTCSHHHHTTTTSBBHHHHHHTTGGCHHHHHHHHGGEEEEE CS
      Cyt-b5   1 tleelskhngkn..dlwvairgkVYDvskflskhpGgesailkyaGkDateafksvvhsekdaekllkkylvGkl 73 
                 t++ l+ +ng +  d+w++++gkVY+++ ++s+hpGg++ +l+ aGkD  ++f    h + +   +l ++lvG l
  EEA22885.1 207 TPSMLKTQNGRKgtDAWTSYNGKVYNITPYVSFHPGGKGELLRGAGKDSGKLFLET-HPWVNWDGILGECLVGIL 280
                 56778999977678******************************************.999999999999999965 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (297 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       669  (0.0373138); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.26s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 1963.63
//
Query:       EEA22886.1  [L=134]
Description: FKBP-type peptidyl-prolyl isomerase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.9e-34  116.3   0.0    7.4e-34  116.0   0.0    1.1  1  FKBP_C    FKBP-type peptidyl-prolyl cis-trans isomerase


Domain annotation for each model (and alignments):
>> FKBP_C  FKBP-type peptidyl-prolyl cis-trans isomerase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.0   0.0   4.1e-38   7.4e-34       2      93 ..      33     123 ..      32     124 .. 0.96

  Alignments for each domain:
  == domain 1  score: 116.0 bits;  conditional E-value: 4.1e-38
                 SCBB-TTCEEEEEEEEEET.TSSEEEEHCCHTSEEEEETTSSSSCHHHHHHHTTSBTT-EEEEEEEGGGTTTTTTBCTTTB.TTSEEEEEEEE CS
      FKBP_C   2 keeakegdtVtvhykgkle.dgkvfdssrsrakplefkvGsgqvikGfeealegmkvGekrtltippelaYgekglaggvippnatLvFeveL 93 
                 +++ ++gdtV++hy g+l+  gk fd s++r++pl+fk+G+g+vikG++++l  m+vGekrtltippel+Yg++ + +  ip+++tLvFe eL
  EEA22886.1  33 NRKTTNGDTVKMHYRGTLAeSGKQFDASYDRGTPLSFKLGAGRVIKGWDQGLLDMCVGEKRTLTIPPELGYGDRAMGP--IPKGSTLVFETEL 123
                 56789*************978*******************************************************55..***********99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (134 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       256  (0.0142785); expected 358.6 (0.02)
Passed bias filter:                      246  (0.0137208); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.27s 00:00:00.67 Elapsed: 00:00:00.42
# Mc/sec: 948.61
//
Query:       EEA22887.1  [L=64]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (64 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       262  (0.0146132); expected 358.6 (0.02)
Passed bias filter:                      185  (0.0103185); expected 358.6 (0.02)
Passed Vit filter:                        12  (0.000669307); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.52u 0.35s 00:00:00.87 Elapsed: 00:00:00.56
# Mc/sec: 344.90
//
Query:       EEA22888.1  [L=1256]
Description: integral peroxisomal membrane protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.1e-98  328.2   0.2    9.4e-98  327.5   0.2    1.3  1  Pex24p           Integral peroxisomal membrane peroxin
    3.4e-14   53.2   0.3    3.4e-14   53.2   0.3    2.7  3  Glyco_trans_2_3  Glycosyl transferase family group 2
    1.7e-13   50.8   0.0    2.7e-13   50.1   0.0    1.3  1  Glycos_transf_2  Glycosyl transferase family 2
    1.3e-12   48.1   0.0    2.4e-12   47.2   0.0    1.4  1  Glyco_tranf_2_3  Glycosyltransferase like family 2
      5e-08   32.6   0.0    8.7e-08   31.8   0.0    1.3  1  Glyco_transf_21  Glycosyl transferase family 21
    2.5e-06   26.3   0.3      0.014   13.9   0.1    2.4  2  Cellulose_synt   Cellulose synthase


Domain annotation for each model (and alignments):
>> Pex24p  Integral peroxisomal membrane peroxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  327.5   0.2  3.1e-101   9.4e-98       3     366 .]     706    1073 ..     704    1073 .. 0.96

  Alignments for each domain:
  == domain 1  score: 327.5 bits;  conditional E-value: 3.1e-101
      Pex24p    3 lsspllssnppqlssrLakifplllildkvlkiltWtnpdktlsfllvytficlvpylelvvlplllllfvvmvpaylyrh.plrksslik...... 92  
                   +spll ++pp ++++La+++p+ll+l+k+ ++ltW++ d++ sfllv+ f+++v+y + ++l+++++l+v+ ++  +y + +++ ss+        
  EEA22888.1  706 RKSPLLVATPPPITRALAHSHPFLLPLNKLAGLLTWSSGDPWASFLLVAGFWAIVLYSDAIILYAGPILVVISLILGMYSRrYSPLSSTGVtgekhg 802 
                  689*****************************************************************************99999999988999999 PP

      Pex24p   93 ..keesknestsegptldeaskeivlnLrdlqnkmedllnpidalekflkelag....fkdenlstllfltllltpililll...srlipwrlillv 180 
                    k++ ++  t+++++ld    eiv+++r+++++++++l p+ ++++fl+++      +++++l++ll++++ +tpi+ill+   +++i++r+++l 
  EEA22888.1  803 nrKQTPESLPTRHQKSLD----EIVETMREFTTRCNIMLGPLREMTDFLSTQSSatsaTTRPALTSLLIRIICITPIWILLTlppFYIITTRRVVLS 895 
                  988888889999999999....*****************************9989999*************************************** PP

      Pex24p  181 lgailltyHpsvkkvllrllwrlkivrlvvkyltgkelkkakskekkeelikelekketadiildespetrkpkrftveifEnqrrwllgkgWtssl 277 
                  +g+i+ltyH+s+++v++ llwr+++vr+++ +ltg++++++k+  k  e++k +++k++a  i  +s+ +  ++rft++++Enqrrw lg+gWt+sl
  EEA22888.1  896 VGTIILTYHSSPARVFRVLLWRSLAVRRICVFLTGLNFSTDKAAVKAAEKSKTVQSKKHATAIATSSKGEA-GVRFTFIVYENQRRW-LGIGWTYSL 990 
                  ****************************************9999999999999*****9999888888887.9**************.********* PP

      Pex24p  278 fsserydwtdetrkalkespsgvdhledvkpPe......dWkWdekkkWrlDlepdewvkeeeekk.GWvYddnkwkepstedslsketRRRrwiR 366 
                  f+ er++wtde   +l+++p+    ++++++P+       W+W+e+++Wr++        +++++  GW+Y+dnkw+++++ ds+ ++tRRR+w+R
  EEA22888.1  991 FPHERTAWTDE---HLNAVPP----KDNFELPDanggnaIWRWVEGSQWRIEGG------DNTSDGgGWIYYDNKWQDGRRGDSWGRYTRRRKWYR 1073
                  ***********...*******....****************************5......3333336****************************9 PP

>> Glyco_trans_2_3  Glycosyl transferase family group 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.2   0.3   1.1e-17   3.4e-14       1     192 [.     176     368 ..     176     374 .. 0.77
   2 ?   -3.6   0.2       2.8   8.5e+03      50     181 ..     475     494 ..     438     504 .. 0.38
   3 ?   -2.9   0.8       1.8   5.5e+03     157     191 ..     734     768 ..     697     782 .. 0.58

  Alignments for each domain:
  == domain 1  score: 53.2 bits;  conditional E-value: 1.1e-17
  Glyco_trans_2_3   1 iilllDaDtvlppdclreiaaela.spevaivqgpvlvm..nvanwleelaalffaedhgkdilvrealgrvvpsvGsgaflrrsalqevggwd 91 
                      +i+ lDaD  +    lr +  ++  + + ++v+    ++  + +++l +   ++++     d +v  +l ++    Gsg++lrr+a+ e+gg++
       EEA22888.1 176 YIASLDADMIPEKRWLRAVMPHMVlDSRLGMVCPSQSYYhtPHNDLLIQNGRSCWN----VD-SVYRSLANFGLNSGSGFVLRREAILEIGGFP 264
                      68889*****************99889*****999777556889999999999886....34.3334666777778****************** PP

  Glyco_trans_2_3  92 gdessvsEDfdmglrlqrkGyrvrfvpeslvkekspltlraalrQrkRwayGc.el..eklillvrllgylgsllwsalplhlallllfsllal 182
                          s+ ED+++++ +++kG+r+ +++e+l +  +p ++ a ++Q  Rw  G  +l  + +++l++++  + s +  ++ l++ +  l++ +  
       EEA22888.1 265 --APSLLEDTYSSVLMMSKGWRTKYISEALQYGLVPESYVASVKQFVRWRVGGvQLamHFKYYLFQRYTGALSMMQRGFGLLMGWGSLSKPFLQ 356
                      ..99************************************************753344333334555555555555555555555555553332 PP

  Glyco_trans_2_3 183 alvl..llllll 192
                      +l++  l+++l+
       EEA22888.1 357 VLLMigLPCQLV 368
                      222223555555 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 2.8
  Glyco_trans_2_3  50 lffaedhgkdilvrealgrvvpsvGsgaflrrsalqevggwdgdessvsEDfdmglrlqrkGyrvrfvpeslvkekspltlraalrQrkRwayG 143
                      + f+                                                                                          
       EEA22888.1 475 MLFD------------------------------------------------------------------------------------------ 478
                      2222.......................................................................................... PP

  Glyco_trans_2_3 144 celeklillvrllgylgsllwsalplhlallllfslla 181
                                            ++ +hl   +++ +la
       EEA22888.1 479 ---------------------LNVIFHL-SIFMSTFLA 494
                      .....................2222333.112222222 PP

  == domain 3  score: -2.9 bits;  conditional E-value: 1.8
  Glyco_trans_2_3 157 gylgsllwsal.plhlallllfsllalalvllllll 191
                      +++g+l ws+  p++  +ll+++++a++l+  +++l
       EEA22888.1 734 KLAGLLTWSSGdPWAS-FLLVAGFWAIVLYSDAIIL 768
                      4555555555424433.3444444443333333333 PP

>> Glycos_transf_2  Glycosyl transferase family 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.1   0.0   8.9e-17   2.7e-13       1     168 [.      86     259 ..      86     261 .. 0.84

  Alignments for each domain:
  == domain 1  score: 50.1 bits;  conditional E-value: 8.9e-17
                      EEEEEESS-.TTTHHHHHHHHHHH.GGCCEEEEEEEEES-SSCHHHHHGGGCHC-TTEEEEEESSS-...HHHHHHHHHHHH--SS......EE CS
  Glycos_transf_2   1 svviptyNe.ektlletlesllaq.dpypdfeiivvDDgStDetveileelakedprvrvirreenv...Gkagalnaglraatgd......yi 83 
                      ++v p++Ne  + l+ t+  +l   +p+++++++v+DDg + e+++++ +l    +r+ +  r++ +    kag+ln++++  ++       yi
       EEA22888.1  86 DIVLPCCNEpLDVLQDTILGVLGVdYPHDKYRVVVADDGASRELQDWVASLK--CQRLYYHARKKPTipdYKAGNLNQAIDFMSTFpggpaeYI 177
                      69*************************************************5..66666666666543238***********99999999**** PP

                      EEEESSEEE-TTHHHHHHHHHHH.TTCEEEEEEEEEECCCCCCCHC-SSEEEECCHCCCCHCCCCCCSTTCSTCCCEEEEHHHHH CS
  Glycos_transf_2  84 lflDaDdepdpdwleklvealekdgadvvlgqrprifgetdeiernkrvgenerlyfkerkrslkgnlsfeigsaallrrealee 168
                      + lDaD +p++ wl+ ++ ++  d + + ++    +   +++    +       +++     +   n   ++gs ++lrrea+ e
       EEA22888.1 178 ASLDADMIPEKRWLRAVMPHMVLDSRLGMVCPSQSYYHTPHNDLLIQ---NGRSCWNVDSVYRSLANFGLNSGSGFVLRREAILE 259
                      **********************9766555555444444444444444...48999999999999999999999999999999855 PP

>> Glyco_tranf_2_3  Glycosyltransferase like family 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   47.2   0.0   8.2e-16   2.4e-12       6     229 ..      87     313 ..      83     314 .. 0.81

  Alignments for each domain:
  == domain 1  score: 47.2 bits;  conditional E-value: 8.2e-16
  Glyco_tranf_2_3   6 vlVptfneed.vlgevlesllaqey..prvevvvvvdesdaetlevaeelaaalpdvrvrvvvnarnl.gstgksralnealravk......sd 89 
                      ++ p+ ne+  vl +++  +l  +y  + ++vvv +d+ ++e  + +      l+  r+  ++  +++  ++ k+ +ln+a++  +       +
       EEA22888.1  87 IVLPCCNEPLdVLQDTILGVLGVDYphDKYRVVVADDGASRELQDWVAS----LKCQRLY-YHARKKPtIPDYKAGNLNQAIDFMStfpggpAE 175
                      678999998658889******6666315599999999999998885544....4544566.566666669*************98877887778 PP

  Glyco_tranf_2_3  90 lvllvDdDtvvePdtlkrllqff.ltpkvgavgtpvfllnrstlvsalgalefaerhlrflaarralg.v.ltlnGsgslirrevlkelegldp 180
                      +++ +D+D + e++ l+++ + + l+++ g+v  ++  ++  +     ++ +   ++ +  ++ r+l  + l  +Gsg++ rre   e++g+ +
       EEA22888.1 176 YIASLDADMIPEKRWLRAVMPHMvLDSRLGMVCPSQSYYHTPHNDLLIQNGR-SCWNVD--SVYRSLAnFgL-NSGSGFVLRREAILEIGGFPA 265
                      *********************************9999888777755555522.345554..44444431414.37******************9 PP

  Glyco_tranf_2_3 181 lflltdDyelglrlrragfrtayvpgaavrevfpsslkayikqrnRwvy 229
                        +l +D  +++ +++ g+rt+y  +a+ + + p+s  a++kq  Rw +
       EEA22888.1 266 -PSLLEDTYSSVLMMSKGWRTKYISEALQYGLVPESYVASVKQFVRWRV 313
                      .9*********************************************65 PP

>> Glyco_transf_21  Glycosyl transferase family 21
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.8   0.0   2.9e-11   8.7e-08      29     172 ..     172     312 ..     140     313 .. 0.82

  Alignments for each domain:
  == domain 1  score: 31.8 bits;  conditional E-value: 2.9e-11
  Glyco_transf_21  29 akydllvisDsdvrvkpdyLeellaal.edpkvglVtslpvgsdakglaaaleaafl.ntlagvlqaklsglgfavGksmalrreaLeaiGGfe 120
                        ++++  +D+d++ ++  L+ ++ ++  d++ g+V+    ++++ +    +++      +  v+ + l+ +g   G+  +lrrea+ +iGGf 
       EEA22888.1 172 GPAEYIASLDADMIPEKRWLRAVMPHMvLDSRLGMVCPSQSYYHTPHNDLLIQNGRScWNVDSVYRS-LANFGLNSGSGFVLRREAILEIGGFP 264
                      457899****************998772679******877777777766667666654678888888.999*********************** PP

  Glyco_transf_21 121 aladeLAeDyalgkllraaGlkvvlspapiaqtsvprrsslrallaRqlrWa 172
                      a    L eD+  + l+ ++G+++   ++++    vp+  s+ a +++ +rW 
       EEA22888.1 265 A--PSLLEDTYSSVLMMSKGWRTKYISEALQYGLVPE--SYVASVKQFVRWR 312
                      *..9************************999999996..5666799*****6 PP

>> Cellulose_synt  Cellulose synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9   0.1   4.7e-06     0.014      12      45 ..      93     126 ..      84     136 .. 0.87
   2 !   10.0   0.0   7.2e-05      0.21     421     495 ..     267     339 ..     256     391 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 4.7e-06
  Cellulose_synt  12 kepplvtantvlsilavdypvekvscyvsddGaa 45 
                      ep  v  +t+l +l vdyp +k  + v+ddGa+
      EEA22888.1  93 NEPLDVLQDTILGVLGVDYPHDKYRVVVADDGAS 126
                     56777999************************97 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 7.2e-05
  Cellulose_synt 421 svtedvltGfkmharGwrsvycvtkrdafkGsapinlsdrlhqvlrwalGsveiffsrnnalfagykkklkller 495
                     s+ ed  +   m ++Gwr+ y         G  p      ++q +rw +G v++ +  +  lf  y++ l +++r
      EEA22888.1 267 SLLEDTYSSVLMMSKGWRTKYISEAL--QYGLVPESYVASVKQFVRWRVGGVQLAMHFKYYLFQRYTGALSMMQR 339
                     7889999999***********86544..469******************************************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1256 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       680  (0.0379274); expected 358.6 (0.02)
Passed bias filter:                      416  (0.0232026); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.02u 0.39s 00:00:01.41 Elapsed: 00:00:00.61
# Mc/sec: 6241.52
//
Query:       EEA22889.1  [L=700]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.6e-05   24.0   0.3    5.6e-05   22.9   0.3    1.5  1  Hepar_II_III  Heparinase II/III-like protein


Domain annotation for each model (and alignments):
>> Hepar_II_III  Heparinase II/III-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.3   3.1e-09   5.6e-05      22     182 ..     439     607 ..     416     665 .. 0.68

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 3.1e-09
                   EEEEEEEECTCTTB.CTTS-S-TTEEEEEETTEESS........---C-SSTTT...HHHHHHHTSGGGSSSEEETTBS--HCCCHHSCCEEEEEEE CS
  Hepar_II_III  22 tvlvvdagppgpgdlsghaHaDtLsfelssggqrli........vdcGtytygg...pewrnaarstaaHNTlvvdgksssrfagkfrlgrraever 107
                    +++++ag     ++  h+  D++ f+l + g+r+           +G+++ ++   ++w  ++++t+  NT+v ++ ++   a ++      ++  
    EEA22889.1 439 LFVAMKAGRGL--GHQTHGNLDAGDFVLDALGERWAgelcqdnyLSPGYFSSEAsdsERWSYYRCGTQGQNTIVYNDSNQVVNAYPSTRFGTTQAGI 533
                   56666666554..2346777777777777777777633222222456777777799666**********************5555444444445555 PP

                   EEESSSEEEEEE..EEEEET.TTTEEEEEEEE.EETTTEEEEEEEEECSEEEEEEEEEEEESTTECEEEETTTTEEEE CS
  Hepar_II_III 108 eeeeggvellaa..ehdgyaapfgvvhrRtll.sldgeslrveDslegsgehepfalrfhlhpdvevslgadgagvll 182
                   ++++ + +++++    +      g++ +R ++   + ++++++D+++    +   ++r h + +v+ s++  g +++l
    EEA22889.1 534 TDDNHDLKYDTSfwVANLTSSNNGTMIQRGVRlLQNRRQVLIQDEFTYTRFGS--QWRMHTNASVTYSNN--GRTAHL 607
                   5555555555555455666999**********76677*********9888775..777777777766665..665533 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (700 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       359  (0.0200234); expected 358.6 (0.02)
Passed bias filter:                      267  (0.0148921); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.75u 0.31s 00:00:01.06 Elapsed: 00:00:00.55
# Mc/sec: 3825.88
//
Query:       EEA22890.1  [L=541]
Description: galactose oxidase precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.8e-20   73.0   0.0      4e-20   71.9   0.0    1.6  1  DUF1929         Domain of unknown function (DUF1929)
    2.2e-06   27.0   0.3    0.00016   21.0   0.2    2.5  2  Glyoxal_oxid_N  Glyoxal oxidase N-terminus
    6.1e-06   26.3   8.7      0.013   15.7   0.0    4.9  5  Kelch_6         Kelch motif
     0.0042   16.6   6.1     0.0058   16.2   0.3    3.7  4  Kelch_1         Kelch motif
     0.0069   16.4   7.4         14    5.8   0.0    5.1  4  Kelch_4         Galactose oxidase, central domain
  ------ inclusion threshold ------
      0.031   14.3   1.1        5.6    7.1   0.2    4.3  4  Kelch_2         Kelch motif


Domain annotation for each model (and alignments):
>> DUF1929  Domain of unknown function (DUF1929)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.9   0.0   1.3e-23     4e-20       1      94 [.     437     535 ..     437     537 .. 0.87

  Alignments for each domain:
  == domain 1  score: 71.9 bits;  conditional E-value: 1.3e-23
     DUF1929   1 RPkissv.ptevkygetftvtvsvekeaeev.kvslvrpgfvTHsvnmdqRlveLevset.......gytvtvtaPpnanvapPGyymlFvvn.dgvpS 89 
                 RP+i ++ +t v+ ++t+tv      +++ + +++l+r+g++THs+n+dqR+v L++se+       + +++vt+P+++++++PG++mlF+++ ++vpS
  EEA22890.1 437 RPQILEIsNTVVNPESTLTVY-----TDGPIeEFALLRYGSATHSINTDQRRVLLSISEDlanfdgvKWKYHVTLPDSPGILIPGFWMLFALDrEQVPS 530
                 9******55559888999988.....678888***********************99444445566799************************99**** PP

     DUF1929  90 vgkwV 94 
                 +++ +
  EEA22890.1 531 ISVEI 535
                 99876 PP

>> Glyoxal_oxid_N  Glyoxal oxidase N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0   0.2   5.4e-08   0.00016      51     134 ..     101     184 ..      96     188 .. 0.80
   2 ?    3.2   0.0     0.014        41     106     135 ..     320     349 ..     304     399 .. 0.86

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 5.4e-08
  Glyoxal_oxid_N  51 ydvatnavrplkvl.t..dtwcssgalladGtlvqtGGfkdgerkvrllspceecdwvelkeelaekRwyatnqiLpdgrvivvGGr 134
                     y++atn+v  ++++ t  + +c   +l++ Gtlv tGG ++ ++    +s+ +   wve ++     R y  +++L dg+++ +GG 
      EEA22890.1 101 YKLATNKVSIYNMTvTdhNMFCPGISLNSVGTLVVTGGSSSEHT--SFYSSVHGGSWVEGPQM-VIGRGYHGQATLSDGQIFTIGGS 184
                     77788877666543122378******************876554..5567778899***9975.5689*****************96 PP

  == domain 2  score: 3.2 bits;  conditional E-value: 0.014
  Glyoxal_oxid_N 106 elkeelaekRwyatnqiLpdgrvivvGGrr 135
                     e+ e ++  R +a ++iLp g+v++ GG +
      EEA22890.1 320 EKIEPMHYARSFANSAILPSGEVFINGGVT 349
                     555667889******************965 PP

>> Kelch_6  Kelch motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.5   0.2    0.0074        22       3      49 ..     120     164 ..     118     165 .. 0.73
   2 !    6.5   0.1    0.0035        11       4      44 ..     168     208 ..     166     215 .. 0.88
   3 ?   -0.3   0.0      0.49   1.5e+03      12      29 ..     285     304 ..     274     329 .. 0.72
   4 !   15.7   0.0   4.5e-06     0.013       4      50 .]     332     383 ..     328     383 .. 0.93
   5 ?   -3.4   0.0       4.7   1.4e+04       5      20 ..     386     403 ..     384     409 .. 0.56

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0074
     Kelch_6   3 aghslvsvg..gkiYifGGytdsspylnkvwvydpetksWeqlpplpvp 49 
                 ++++ +s +  g++++ GG++   ++++  +  ++  +sW ++p++ ++
  EEA22890.1 120 MFCPGISLNsvGTLVVTGGSSS--EHTS--FYSSVHGGSWVEGPQMVIG 164
                 6777778885569*******87..3333..5556999999999999665 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0035
     Kelch_6   4 ghslvsvggkiYifGGytdsspylnkvwvydpetksWeqlp 44 
                 ++++++ +g+i+ +GG+  +++  +  +v+d+   +W+ lp
  EEA22890.1 168 HGQATLSDGQIFTIGGSWSGGEGNRNGEVLDVAGTTWSSLP 208
                 5789999**********999999999999999999999988 PP

  == domain 3  score: -0.3 bits;  conditional E-value: 0.49
     Kelch_6  12 gkiYifGGytds..spylnk 29 
                 gki  +GG+t +   p+++ 
  EEA22890.1 285 GKILTLGGATSYtdAPASRA 304
                 88999999998665555555 PP

  == domain 4  score: 15.7 bits;  conditional E-value: 4.5e-06
     Kelch_6   4 ghslvsvggkiYifGGytds.....spylnkvwvydpetksWeqlpplpvpr 50 
                 ++s++++ g ++i GG t +     ++ ++ +++++p+tk++++l+  p+pr
  EEA22890.1 332 ANSAILPSGEVFINGGVTWAkqwtdTNVTSIPELWNPQTKRFTKLAATPIPR 383
                 789999***********8669****************************998 PP

  == domain 5  score: -3.4 bits;  conditional E-value: 4.7
     Kelch_6   5 hslvs.vgg.kiYifGGy 20 
                 hs+++   + ++ + GG 
  EEA22890.1 386 HSFAIlLPDaTVLVGGGG 403
                 555333444266666665 PP

>> Kelch_1  Kelch motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.1      0.21   6.2e+02      12      27 ..     131     148 ..     131     151 .. 0.72
   2 !   16.2   0.3   1.9e-06    0.0058       7      43 ..     171     208 ..     165     210 .. 0.91
   3 ?   -3.7   0.0       3.2   9.4e+03      10      19 ..     283     292 ..     282     292 .. 0.86
   4 ?    0.0   0.0      0.22   6.6e+02      14      43 ..     342     377 ..     338     378 .. 0.78

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.21
                 TEEEEEEEBCS..SSBEE CS
     Kelch_1  12 gkiYviGGsdg..gnals 27 
                 g + v GGs++   ++ s
  EEA22890.1 131 GTLVVTGGSSSehTSFYS 148
                 5789******97544444 PP

  == domain 2  score: 16.2 bits;  conditional E-value: 1.9e-06
                 EEEETTEEEEEEEBCS.SSBEEEEEEEETTTTEEEEEC CS
     Kelch_1   7 avvvggkiYviGGsdg.gnalssvevyDpetntWrelp 43 
                 a+  +g+i+ iGGs + g+  ++ ev+D+   tW+ lp
  EEA22890.1 171 ATLSDGQIFTIGGSWSgGEGNRNGEVLDVAGTTWSSLP 208
                 66789******************************999 PP

  == domain 3  score: -3.7 bits;  conditional E-value: 3.2
                 ETTEEEEEEE CS
     Kelch_1  10 vggkiYviGG 19 
                 + gki  +GG
  EEA22890.1 283 LHGKILTLGG 292
                 679******9 PP

  == domain 4  score: 0.0 bits;  conditional E-value: 0.22
                 EEEEEEBCS......SSBEEEEEEEETTTTEEEEEC CS
     Kelch_1  14 iYviGGsdg......gnalssvevyDpetntWrelp 43 
                 +++ GG          n +s  e ++p t+ +++l+
  EEA22890.1 342 VFINGGVTWakqwtdTNVTSIPELWNPQTKRFTKLA 377
                 5555666666677778999999*******9999886 PP

>> Kelch_4  Galactose oxidase, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0     0.045   1.3e+02      11      24 ..     129     142 ..     120     151 .. 0.74
   2 ?    1.2   1.8      0.12   3.7e+02       2      44 ..     165     207 ..     164     214 .. 0.75
   3 !    5.3   0.1    0.0068        20       5      47 ..     331     379 ..     328     380 .. 0.78
   4 !    5.8   0.0    0.0048        14       1      20 [.     382     402 ..     382     410 .. 0.90

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.045
     Kelch_4  11 pdgtiylfGGrged 24 
                   gt++++GG +++
  EEA22890.1 129 SVGTLVVTGGSSSE 142
                 459*******9987 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.12
     Kelch_4   2 Raghs.atsipdgtiylfGGrgedgtllndlylldlstntWrrl 44 
                 R++h+ at   dg i+ +GG  + g+   +  +ld++  tW+ l
  EEA22890.1 165 RGYHGqATLS-DGQIFTIGGSWSGGEGNRNGEVLDVAGTTWSSL 207
                 8888888888.699999999877775555556777777777766 PP

  == domain 3  score: 5.3 bits;  conditional E-value: 0.0068
     Kelch_4   5 hsatsi.pdgtiylfGGrgedg....tllndl.ylldlstntWrrlgsl 47 
                 ++  +i p+g++++ GG ++      t +  +  l++ +t+++++l++ 
  EEA22890.1 331 FANSAIlPSGEVFINGGVTWAKqwtdTNVTSIpELWNPQTKRFTKLAAT 379
                 556666799***********87999955555559***********9664 PP

  == domain 4  score: 5.8 bits;  conditional E-value: 0.0048
     Kelch_4   1 pRaghs.atsipdgtiylfGG 20 
                 pR +hs a+ +pd t+ + GG
  EEA22890.1 382 PRSYHSfAILLPDATVLVGGG 402
                 8*****88888******9997 PP

>> Kelch_2  Kelch motif
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.1   0.0      0.75   2.2e+03      18      46 ..      86     114 ..      73     116 .. 0.82
   2 ?    7.1   0.2    0.0019       5.6       5      32 ..     169     197 ..     165     209 .. 0.70
   3 ?    0.4   0.0      0.24   7.2e+02      10      23 ..     283     298 ..     278     307 .. 0.77
   4 ?    0.6   0.0      0.21   6.3e+02       6      46 ..     334     377 ..     329     380 .. 0.69

  Alignments for each domain:
  == domain 1  score: -1.1 bits;  conditional E-value: 0.75
     Kelch_2  18 GGahtdnpnlsssdvhvldlekhvWeevt 46 
                  G++++np++    ++ l ++k +  ++t
  EEA22890.1  86 FGSEPGNPGRTLTAFYKLATNKVSIYNMT 114
                 3558999**99999999999998877776 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0019
     Kelch_2   5 hsssvpggkiyvvGGa.htdnpnlsssdv 32 
                   ++ ++g+i+ +GG+  ++++n+  + +
  EEA22890.1 169 GQATLSDGQIFTIGGSwSGGEGNRNGEVL 197
                 567889**********9666666655555 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.24
     Kelch_2  10 pggkiyvvGGa..htd 23 
                 + gki+  GGa  +td
  EEA22890.1 283 LHGKILTLGGAtsYTD 298
                 669********66555 PP

  == domain 4  score: 0.6 bits;  conditional E-value: 0.21
     Kelch_2   6 sssvpggkiyvvGGa.....htdnpnlsssdvhvldlekhvWeevt 46 
                 s+  p g +++ GG+      td ++ s+  +  ++++++++++++
  EEA22890.1 334 SAILPSGEVFINGGVtwakqWTDTNVTSIPEL--WNPQTKRFTKLA 377
                 56677777888888877777666666666666..888888888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (541 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       409  (0.0228122); expected 358.6 (0.02)
Passed bias filter:                      334  (0.018629); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.61u 0.29s 00:00:00.89 Elapsed: 00:00:00.49
# Mc/sec: 3343.29
//
Query:       EEA22891.1  [L=182]
Description: hypothetical protein PMAA_094960 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
  ------ inclusion threshold ------
      0.039   14.0   0.2      0.068   13.2   0.2    1.4  1  DUF1249    Protein of unknown function (DUF1249)
      0.092   13.3   0.0       0.95   10.0   0.0    2.2  2  Soc        Small outer capsid protein
       0.12   12.4   0.1       0.18   11.8   0.1    1.2  1  Levi_coat  Levivirus coat protein


Domain annotation for each model (and alignments):
>> DUF1249  Protein of unknown function (DUF1249)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   0.2   1.1e-05     0.068      34      67 ..      57      91 ..      35     106 .. 0.86

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.1e-05
     DUF1249 34 arYTttveleqesee.lellkkpkltvRlYhDArm 67
                  YT ++e+++++ e ++++++p+++v  Y D ++
  EEA22891.1 57 YDYTAEIEVTKDEIEeVTWISEPQVEVSYYADLKL 91
                47********999888****************987 PP

>> Soc  Small outer capsid protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0      0.12   6.9e+02      24      47 ..      80     103 ..      62     115 .. 0.83
   2 ?   10.0   0.0   0.00016      0.95      24      42 ..     143     161 ..     128     171 .. 0.86

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.12
                 EEEHHHHHHS---SSSSEEEEEES CS
         Soc  24 svafplysdvhkisgahyqtfpse 47 
                  v    y+d++ i  a  qt  s+
  EEA22891.1  80 QVEVSYYADLKLIRTAFIQTKFSD 103
                 466778999999999999996665 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.00016
                 EEEHHHHHHS---SSSSEE CS
         Soc  24 svafplysdvhkisgahyq 42 
                  +afp+y   h+isg  y+
  EEA22891.1 143 KMAFPIYDRRHQISGMDYD 161
                 47**************997 PP

>> Levi_coat  Levivirus coat protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.1     3e-05      0.18      47      99 ..      44      96 ..      32     107 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 3e-05
                .EEEEEEEESSSEEEEEEEEEEEEEEEEEETTEEEEEEEEEEEEEEEEEEETT CS
   Levi_coat 47 rvtisvrqssanrkkykvkvkvqkvasqtvsGvedPvvarrayldvelsitiy 99
                 v   v + s +  +y+ +++v k     v+ + +P v  + y+d++l  t +
  EEA22891.1 44 TVMYGVMRVSHQAYDYTAEIEVTKDEIEEVTWISEPQVEVSYYADLKLIRTAF 96
                37788999**************************************9987776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (182 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       364  (0.0203023); expected 358.6 (0.02)
Passed bias filter:                      295  (0.0164538); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.39u 0.29s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 1295.00
//
Query:       EEA22892.1  [L=258]
Description: hypothetical protein PMAA_094970 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (258 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       368  (0.0205254); expected 358.6 (0.02)
Passed bias filter:                      332  (0.0185175); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1734.76
//
Query:       EEA22893.1  [L=135]
Description: hypothetical protein PMAA_094980 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (135 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       410  (0.022868); expected 358.6 (0.02)
Passed bias filter:                      318  (0.0177366); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.26s 00:00:00.66 Elapsed: 00:00:00.43
# Mc/sec: 953.71
//
Query:       EEA22894.1  [L=239]
Description: cochaperone Pam16 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.6e-33  113.4   0.4    1.1e-32  112.8   0.4    1.3  1  Pam16     Pam16


Domain annotation for each model (and alignments):
>> Pam16  Pam16
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  112.8   0.4     6e-37   1.1e-32       1     117 [.      98     220 ..      98     230 .. 0.85

  Alignments for each domain:
  == domain 1  score: 112.8 bits;  conditional E-value: 6e-37
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXX.XXXXXXXXXXXXXXXX-HHHHHHHHT--G.......--SHHHHHHHHHHHHHHT-CCCTS CS
       Pam16   1 makraalkvivagtqvvgkalaralrqeiaaaraaadartsasereaaksnlkGisleeslkilnvee.......dlnreevekryehlfevndkskGG 92 
                 ma+r+   ++v+gt+v+g+a+a+a++q+ a+++ a++  ++    +a+    +G++l+e++kilnv+        + + e v +r++ lf++nd +kGG
  EEA22894.1  98 MAHRILTTLVVTGTRVFGRAFAEAYKQASASSKYATEM-KKGNVTGASTYASNGLTLDEACKILNVKPpqaaagrEAQLESVMERFKKLFDINDPEKGG 195
                 9****************************998888887.33333455555555**************8778888788899******************* PP

                 -HHHHHHHHHHHHHHHHHHHHHH-X CS
       Pam16  93 slylqskvfrakerldeelkieeke 117
                 s+ylqsk++ra+er++ el+  e++
  EEA22894.1 196 SFYLQSKILRARERIEMELRETERK 220
                 *******************665443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (239 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       626  (0.0349155); expected 358.6 (0.02)
Passed bias filter:                      453  (0.0252663); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.25s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 1702.80
//
Query:       EEA22895.1  [L=414]
Description: L-galactose dehydrogenase (L-GalDH), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.1e-57  193.3   0.0    6.3e-57  193.0   0.0    1.1  1  Aldo_ket_red  Aldo/keto reductase family


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  193.0   0.0   3.5e-61   6.3e-57       1     285 [.      41     353 ..      41     360 .. 0.92

  Alignments for each domain:
  == domain 1  score: 193.0 bits;  conditional E-value: 3.5e-61
                   .EEEE-SSS-ST.TS-HHHHHHH...HHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH....-TTTGGG-EEEEEE--SSSTTSSSS-HHHHHHHH CS
  Aldo_ket_red   1 elglGtwqlgskeeiskeealel...lrraleaGinffDtAevYgkgqseellGealkk....srkkreeviiatKvdlrdaeiksglskeniresl 90 
                   +l+lGt++++ + +++++ +l     ++ral+aGi++fDt+++Y  g+see+lG+al++     +++r ++ + tKv +r ae ++++s++++r s+
    EEA22895.1  41 PLVLGTATFNIQ-YNDDPFSLPSvsiVHRALSAGIRAFDTSPYY--GPSEEILGQALASekvaTEFPRHTYQLLTKV-GRVAESSFDYSPAWVRYSI 133
                   699********9.8888887654455******************..*******************************.******************* PP

                   HHHHHHHT-S-EEEEEE-S--TTS-.HHHHHHHHHHHHH....TTSEEEEEEES--HHHHHHH......HHTTT--EEEEE-B-BTT-HHHHTTHHH CS
  Aldo_ket_red  91 eeslkrLgtdyvDllllHrpdpslpsieevldaleelvk....eGkiraiGvSnfsveqleka......kkkkkvkivavqveynllreleeeglle 177
                   ++sl+rL+tdy+D++++H++++ +   +ev++a+ el++      +ir++G+S+++ve l ++      ++ +++++v+++++ynl++ + ++++l 
    EEA22895.1 134 KRSLRRLHTDYLDVVYCHDVEFVSA--AEVVEAVRELRRirdeDASIRYVGISGYPVEVLAELaelvlrETGEPLDVVMSYANYNLQNTRLATKVLA 228
                   *************************..************99999*******************************************9999999999 PP

                   HHHHTT-EEE.EBSTTGGGTTGTTTSS---SSSCCC-------TS-HHHHHHHHHHHHHHHH.TT--HHHHHHHHHTTS.................. CS
  Aldo_ket_red 178 lckkkgvpli.aysplggGlltgkyqseedkedkeprkdlkrdertsknldaaeelselake.hgvslaqlalryalsq.................. 254
                    +++ gv+++ ++s+lg+Gll+g+++ + ++ +k             + +da++++se+ +e ++++l+ la ry l++                  
    EEA22895.1 229 RLRAAGVDVVpNASILGMGLLRGQSVFDWHPAPK-------------GLRDATQKASEVLREqQNEKLESLATRYGLESwiregsavgvyghpleat 312
                   99999*****************999988777654.............5679***********8888***********99998888887777777777 PP

                   ..........TT-SEEEE--SSHHHHHHHHGGGG----HHH CS
  Aldo_ket_red 255 ..........pavgivipgasnieqlednldalelklseee 285
                             ++ g++++g+sn++++++ ++ +   l++ +
    EEA22895.1 313 dgsapklsngQQLGVTVVGVSNVKEVDELVAIYREVLDDVV 353
                   77776666666*****************9999977777765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (414 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       561  (0.0312901); expected 358.6 (0.02)
Passed bias filter:                      526  (0.0293379); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.27s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 2672.30
//
Query:       EEA22896.1  [L=277]
Description: O-methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.7e-12   47.0   0.0    2.3e-12   46.5   0.0    1.1  1  Methyltransf_3   O-methyltransferase
    5.3e-10   40.3   0.0    1.1e-09   39.2   0.0    1.6  1  Methyltransf_24  Methyltransferase domain
  ------ inclusion threshold ------
        0.1   12.3   0.0       0.19   11.4   0.0    1.5  1  CmcI             Cephalosporin hydroxylase


Domain annotation for each model (and alignments):
>> Methyltransf_3  O-methyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.5   0.0   3.9e-16   2.3e-12      18     162 ..      46     194 ..      32     211 .. 0.89

  Alignments for each domain:
  == domain 1  score: 46.5 bits;  conditional E-value: 3.9e-16
                     HHTTTST.TGGGS--HHHHHHHHHHHHHHT--EEEEE--TTSHHHHHHHTTS-TT-..EEEEEES-HHHHHHHHHHHHHTT-GGGEEEEES-HHH CS
  Methyltransf_3  18 eatakktdlsemevsvdegqfLslLvklvnakrvleiGvftGyslLatalalPeDG..kilaididreayeialkfiqkagvaekieliegdalk 110
                     ++  + t+   m+++ ++g fL  ++       v+e+G f Gys++ +  al  +G  + l+++ ++ ++ +a  +i+ ag+ + + ++++ + k
      EEA22896.1  46 NF-SQATGKYLMTIGSKKGAFLADIIATRKPSTVVELGGFVGYSAIYLGDALRANGgkRYLSLELNPVNASVANLLIELAGLRDVVTIHVAASHK 139
                     43.34556778************************************99999988766799********************************** PP

                     HHHHHHTSSS---EEEEEE-S-GGGHH..HHHHHHHHTEEEE.EEEEEE-TTGGG CS
  Methyltransf_3 111 vLeelvkdkklpefDfifvDaDkssyv..nyyeklleLvkvG.gliaiDntLWeG 162
                     +L  +vkd+   + +++++D  k+ y    +  + l L+k G  ++a Dn L  G
      EEA22896.1 140 MLAGFVKDNVIDHVEVMLIDHWKDRYLpdLWLMENLGLLKPGvTVLAADNCLRPG 194
                     **************************633588999******955899***99766 PP

>> Methyltransf_24  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.2   0.0   1.9e-13   1.1e-09       1     103 [.      79     186 ..      79     189 .. 0.84

  Alignments for each domain:
  == domain 1  score: 39.2 bits;  conditional E-value: 1.9e-13
  Methyltransf_24   1 vEiGvysGvstlwllralrrngagrlvavdhdpgaeeaaalare.aglddrvrlikadseealasla....agsiDllfiDgghaaeavledle 89 
                      vE+G + G+s+++l++alr+ng  r+++++ +p  + +a+l+ e agl+d+v++++a s++ la++      + + +++iD  h ++++l+dl 
       EEA22896.1  79 VELGGFVGYSAIYLGDALRANGGKRYLSLELNPVNASVANLLIElAGLRDVVTIHVAASHKMLAGFVkdnvIDHVEVMLID--HWKDRYLPDLW 170
                      8********************************655555555558*******************99975554456699999..9********98 PP

  Methyltransf_24  90 allp..rlapggvvlf 103
                      ++++  +l+pg +vl 
       EEA22896.1 171 LMENlgLLKPGVTVLA 186
                      8854338999998875 PP

>> CmcI  Cephalosporin hydroxylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   3.1e-05      0.19      26      59 ..      68     101 ..      64     161 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 3.1e-05
        CmcI  26 eliwelkPdliietGiahGGsalfsasllallks 59 
                  +i   kP++++e+G   G sa++  + l+  ++
  EEA22896.1  68 DIIATRKPSTVVELGGFVGYSAIYLGDALRANGG 101
                 79999********************999887743 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (277 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       307  (0.0171231); expected 358.6 (0.02)
Passed bias filter:                      301  (0.0167884); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.41
# Mc/sec: 2022.71
//
Query:       EEA22897.1  [L=488]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-23   81.8  32.1    4.3e-23   81.8  32.1    1.5  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.8  32.1   2.4e-27   4.3e-23       2     352 ..      62     423 ..      61     424 .. 0.82
   2 ?   -2.1   0.2     0.076   1.4e+03     250     273 ..     442     465 ..     433     475 .. 0.50

  Alignments for each domain:
  == domain 1  score: 81.8 bits;  conditional E-value: 2.4e-27
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslw.lllvlrvlqGlga 99 
                 +l+++ ++l+r++lg a +++l +dlg+ + +++lll l+++ ++++ +p+  l+  +++  v+ l +l++++  +++  a+  +  ++++r++ G ++
  EEA22897.1  62 SLVYLTHSLDRANLGNAKTSTLERDLGLVGNQYSLLLILFYIPYSIFGIPATILAKQYSSALVIPLLVLGWGSL-AMIQAAAKDFgGMMACRIILGTME 159
                 789999****************************************************9999************.55553577777************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg.....Wravfyilaivsllafvlfllllpeepperkrkspkeee..... 188
                 ++++p ++ +++  ++k+e ++ ++++ ++  +++++  l++  +  ++      W+++f+i +++s+  + ++l+ lp++  +++ ++p++       
  EEA22897.1 160 AGFLPCAIFYLSMFYTKTELAKRLSVFFLMGFIASAISGLISWGVF-QWDrslkgWQYLFLIEGGISVGIAFIVLIALPDSVQKSRYFTPAQIQcaslr 257
                 ***********************************99988888777.66679999***************99999999999999999999888788866 PP

       MFS_1 189 ...kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlgls....glllaglllallalvgailallagrlsdrlgrrrrllla 280
                    +   ++++++   ++l d  +w++ ++ ll ++g ++++ +lp++  ++l  +    +l+++g     + l ga+++ ++ ++sd ++   r l++
  EEA22897.1 258 lehNPENEFNFKE-GFIVLMDWKIWLFALSGLLYGVGATSTSNFLPVM-IQRLTQDtvraNLYTIG-----PNLTGAFFMYVSCWVSDSIQQ--RGLVS 347
                 5554555555555.66677777778777777777788888*******5.66666662333344444.....5555555599*******9766..***** PP

       MFS_1 281 llllllaalglallavt.....ssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfntagslggalg 352
                 +++++++ +g++ll++       +   +l  l+++G+++ +  +++++ a+  + ++ ++ a+g+ +t  +lgg+++
  EEA22897.1 348 IVVVSVSMIGWILLGTLdlvdhVKLGYFLTYLLTFGTFVPLLLVPAWVGANTRT-TSSRAVALGFLSTSANLGGIVS 423
                 *****************8885544444444666688877777555555555444.3999***************986 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 0.076
       MFS_1 250 lallalvgailallagrlsdrlgr 273
                 + l+++v+++++++  ++  r++r
  EEA22897.1 442 VFLCQAVFVMICIVMRAVYARMNR 465
                 444444444444444444444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (488 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       683  (0.0380947); expected 358.6 (0.02)
Passed bias filter:                      304  (0.0169558); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 3288.04
//
Query:       EEA22898.1  [L=308]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.5e-24   85.8   8.5    4.7e-24   85.3   8.5    1.1  1  Cad            Cadmium resistance transporter
  ------ inclusion threshold ------
       0.73    9.9   7.0         15    5.8   0.0    3.3  3  Insulin_TMD    Insulin receptor trans-membrane segment


Domain annotation for each model (and alignments):
>> Cad  Cadmium resistance transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.3   8.5   5.3e-28   4.7e-24       3     183 ..      16     195 ..      14     200 .. 0.87

  Alignments for each domain:
  == domain 1  score: 85.3 bits;  conditional E-value: 5.3e-28
         Cad   3 ataldlliillllfarlkskkek..ldiylGqylGsvalvlvsllfafvlnyvpeewilGllGlipiylGikvll..lGdedeeeelkeelekkkakkl 97 
                  t +d + +l+ lfa++++ + +  l i lG+y+G ++++++s++      ++p+e  +G++Gl+pi+lGi  ll  l  ++eee  k +l      k 
  EEA22898.1  16 ITNIDAMFVLVTLFAEASACRTMtpLMIILGEYIGFTVIIIISMIGFGASLLIPSEP-IGFFGLLPILLGIWRLLnlLVPNQEEESEKTKLA---GVKS 110
                 699*************9987765226899**************99877778999987.5************765411455666666666676...4456 PP

         Cad  98 lftvalitiascGadniglfvpyfvtlslanllvallvflililllvllakklakipsvgevlekysrwivalvyivlGlyillen 183
                 +f v lit+   G+dnig +vp f+  ++a++ + ++++ il+ + +l+a  + +  ++ ++ ++y r++v+++y+ lG yi+ ++
  EEA22898.1 111 VFKVSLITLMN-GGDNIGTYVPLFAQANAAEIAIYVITYYILVGVWCLVAFLVMRQKHILKIAKRYARVVVPFLYLGLGSYIIEKS 195
                 899*******9.*********************************************************************98665 PP

>> Insulin_TMD  Insulin receptor trans-membrane segment
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   1.5      0.34   3.1e+03      17      34 ..      43      60 ..      37      66 .. 0.54
   2 ?    5.6   1.0    0.0019        17      10      42 ..     135     166 ..     129     168 .. 0.83
   3 ?    5.8   0.0    0.0017        15      18      42 ..     217     241 ..     206     243 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.34
  Insulin_TMD 17 IvigPviciillllviga 34
                 I+ g  i + +++++  +
   EEA22898.1 43 IILGEYIGFTVIIIISMI 60
                 666665544333333332 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0019
  Insulin_TMD  10 dpsnivkIvigPviciillllvigavfvvvkKr 42 
                  +  n + I i  +   il+ + + ++f+v++ +
   EEA22898.1 135 Q-ANAAEIAIYVITYYILVGVWCLVAFLVMRQK 166
                  4.4889999999999***************987 PP

  == domain 3  score: 5.8 bits;  conditional E-value: 0.0017
  Insulin_TMD  18 vigPviciillllvigavfvvvkKr 42 
                  v++    ++ll  v+  +++ ++Kr
   EEA22898.1 217 VMAVTTAFVLLTCVGTMAWLTLRKR 241
                  55556679****************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (308 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       744  (0.041497); expected 358.6 (0.02)
Passed bias filter:                      360  (0.0200792); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.26s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 2027.66
//
Query:       EEA22899.1  [L=689]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.5e-24   86.5   0.3    3.7e-24   85.2   0.3    1.7  1  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   85.2   0.3   2.1e-28   3.7e-24       3     266 ..      83     331 ..      81     332 .. 0.90

  Alignments for each domain:
  == domain 1  score: 85.2 bits;  conditional E-value: 2.1e-28
  Fungal_trans   3 rffsnfhpqfpilhkpsflpkt..ssenssksayaspllllailalGalfsesetkesnssltses......qefiafplraeilihedfsspsssl 91 
                    +f+ f++ +p+++++ f+++   ++++++++ +a  +l++++l+lG+  +  e  +   s++            + ++  a+ ++h+ f+ +++ l
    EEA22899.1  83 CYFTTFNNVYPVINRNVFDSYLerQYSSNPPTSSAWYALFNSVLCLGSIRTTGERERHVRSSRLIDytsvahETGVGYFRNASCCFHDLFFNQTN-L 178
                   6**************9999999988999999999999999*******976655555554444444469999877888888999999888888888.* PP

  Fungal_trans  92 wilqsLlllelyektssdralherhhgvavr.larslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPc 187
                    + q+  l+ +  + ss+ ++  +++  a r +++slgLhr     g      l++ee+e+rr+++w  ++l+k i+  lGrp+ ++d++i ++LP 
    EEA22899.1 179 MAMQAITLMMFITISSSN-PQISYTLTSAGRnIVYSLGLHRSLDGAG------LSPEEFEQRRNVFWVFYMLEKAICHNLGRPSVINDDDIAVELPP 268
                   ************999998.9999999999999***************......*******************************99*********** PP

  Fungal_trans 188 ddddlwesddaseetlvetklsneeksrkiasfllaLkkilskiagsllsiekqlqqrdlqseklswveeleraldnWr 266
                       l  s + ++++++              +  ++L+ i s i+ +l+s ++q++ ++ +    +++ +l++ l++Wr
    EEA22899.1 269 KKPGLLRSPSGAGIYDIF-------------QDSITLAIIGSRIYTELYSASSQTKSEEYR---MKMLSKLDNHLQRWR 331
                   ***9****9999999998.............889999999999************999999...99999*********8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (689 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       472  (0.0263261); expected 358.6 (0.02)
Passed bias filter:                      303  (0.0169); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.28s 00:00:00.86 Elapsed: 00:00:00.45
# Mc/sec: 4593.50
//
Query:       EEA22900.1  [L=1015]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.4e-09   35.9   0.1    1.5e-08   34.7   0.1    1.7  1  NACHT         NACHT domain
    2.7e-08   34.2   0.0    1.3e-07   32.0   0.0    2.2  1  AAA_22        AAA domain
    1.1e-06   29.2   0.0    4.4e-06   27.2   0.0    2.1  1  AAA_16        AAA ATPase domain
    6.7e-05   23.3   0.0     0.0055   17.1   0.0    3.7  4  AAA           ATPase family associated with various cellular 
    0.00024   20.4   0.0     0.0023   17.2   0.0    2.2  2  KAP_NTPase    KAP family P-loop domain
     0.0066   16.4   0.0      0.019   14.9   0.0    1.7  1  ATPase_2      ATPase domain predominantly from Archaea
  ------ inclusion threshold ------
      0.021   14.8   0.0       0.05   13.6   0.0    1.6  1  TsaE          Threonylcarbamoyl adenosine biosynthesis protei
      0.037   14.4   0.0       0.12   12.8   0.0    1.9  1  RNA_helicase  RNA helicase
      0.089   12.3   0.2        1.3    8.5   0.0    2.2  2  Cir_Bir_Yir   Plasmodium variant antigen protein Cir/Yir/Bir
        0.1   13.1   0.0       0.76   10.3   0.0    2.4  3  ABC_tran      ABC transporter
       0.11   12.4   0.0        0.3   11.0   0.0    1.7  1  Rad17         Rad17 P-loop domain


Domain annotation for each model (and alignments):
>> NACHT  NACHT domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.7   0.1   9.3e-12   1.5e-08       1     139 [.     376     531 ..     376     576 .. 0.74

  Alignments for each domain:
  == domain 1  score: 34.7 bits;  conditional E-value: 9.3e-12
                 SCEEEEC-TTTCHHHHHHHHHHHHCTS-SCCCC-SEEEEEETTTTTTS-...-HCHHHCCCCTS--SSS-C.........................CHH CS
       NACHT   1 rlvilqGeaGsGKTtLlqklalawaegklpqgafklvFflslrelsrsgnarsladllfsqlpepaapvse.........................vwa 74 
                 r++++ G+ G+GKT+L+  l++++ ++  +q   + ++   +r+ ++ ++++ l +l+ s l+++ +  ++                         + +
  EEA22900.1 376 RQLAICGPMGCGKTVLMTFLVDELTRQSTYQLPTPKILSYYCRDNETGETIYILSTLILSLLQHLPGLKKPfyewygealvsgtnpaastskmgalMQK 474
                 678999*************************999999999999999988889999*999999999999999999**************99988884444 PP

                 HHCCSCCCEEEEEE-STT-SS-TCH.........HHHHHCTTTTT--EEEEEEECCCHHHHCTTS CS
       NACHT  75 vllelperlLlilDglDelvtdlgqkekqpvrtlLselirkkllpeasllltvrpralrdleeql 139
                 +l ++ + + +++DglDe+ ++ +     ++ + L++  r    p+ + +l+ r ++   +   l
  EEA22900.1 475 LLKSVDRPIFILIDGLDECDSKSQR----SLLDFLKRSARD--TPGLKSILSFRREKK--ILDRL 531
                 4445555666899*******95555....666666665555..555555555555443..44444 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.0   0.0     8e-11   1.3e-07       8     127 ..     378     519 ..     374     526 .. 0.78

  Alignments for each domain:
  == domain 1  score: 32.0 bits;  conditional E-value: 8e-11
      AAA_22   8 lvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsstsskdl...lrellralglelka..................erlsseellealeqa 85 
                 l+++G+ G+GKT+l+  l+++l++++  + + p+++++++   ++ +++    + +l+ l+  l +                  + +s++ + +++++ 
  EEA22900.1 378 LAICGPMGCGKTVLMTFLVDELTRQSTYQLPTPKILSYYCRDNETGETIyilSTLILSLLQ-HLPGlkkpfyewygealvsgtnPAASTSKMGALMQKL 475
                 79********************988777779999998888888855555110333444444.34447899*************99************** PP

      AAA_22  86 lraravielliiDEaqhlr..s.eealeeL.rsllnlsrkgvqliL 127
                 l++ +++ +++iD  +  +  s   +l +L rs  +  + g++ iL
  EEA22900.1 476 LKSVDRPIFILIDGLDECDskSqRSLLDFLkRSARD--TPGLKSIL 519
                 *****************9876347888888444444..55555555 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.2   0.0   2.7e-09   4.4e-06      23     164 ..     374     511 ..     366     519 .. 0.71

  Alignments for each domain:
  == domain 1  score: 27.2 bits;  conditional E-value: 2.7e-09
      AAA_16  23 rpelvllsGesGvGKsslvrellralekd......ggiflrgkcdqlesaipysalaqalareellrqlldeaesaeleawrekleealaavpelagae 115
                 +++ + + G+ G+GK+ l++ l ++l+++          l+  c+++e++ + ++l +++   +ll+ l   ++   + +w  + + + +     ++a+
  EEA22900.1 374 GSRQLAICGPMGCGKTVLMTFLVDELTRQstyqlpTPKILSYYCRDNETGETIYILSTLI-L-SLLQHLPGLKK--PFYEWYGEALVSGT----NPAAS 464
                 44778999*********************6666654455999999997775555555555.5.88888888833..46666554444333....23333 PP

      AAA_16 116 asrllellkrllallsrderplvlvlDdlqwadeaslql.laaLlrlles 164
                  s + +l+++ll   ++ +rp+ +++D l+  d+ s+   l++L r++ +
  EEA22900.1 465 TSKMGALMQKLL---KSVDRPIFILIDGLDECDSKSQRSlLDFLKRSARD 511
                 356666666666...66688**************9988868888777654 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0      0.76   1.2e+03      51      89 ..     224     262 ..     192     288 .. 0.67
   2 ?   -1.1   0.0       1.4   2.3e+03      27      67 ..     294     336 ..     263     355 .. 0.71
   3 !   17.1   0.0   3.4e-06    0.0055       3      99 ..     380     511 ..     378     545 .. 0.62
   4 ?   -3.4   0.0       7.2   1.2e+04      37      66 ..     899     928 ..     887     928 .. 0.67

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.76
                 HHHHHTSTSEEEEEETGGGHHHHH.TTCCCHHHHHHHHHH CS
         AAA  51 keakekakpsilfiDEidalaksr.sgseseeeervvnqL 89 
                 +++k +    i  iD+ d l+++   ++ ++   +v ++L
  EEA22900.1 224 AKIKDMH-ERISYIDDCDTLGQKTnGQNIHTALVSVYKKL 262
                 3344443.58889*******99993333333333444444 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 1.4
                 EEEETTTCSSSSTTHHHHHHHHHHHHHHHTS..TSEEEEEETG CS
         AAA  27 leisgsellskyvgesekkirelfkeakeka..kpsilfiDEi 67 
                 + ++  +  + ++g+ ++ ++++++e+++    ++ il++D+ 
  EEA22900.1 294 IAVDFVRSSEALQGHVSNATAKILDEMRTVLydAKIILWLDNN 336
                 4444444444478888899999999988888876799999975 PP

  == domain 3  score: 17.1 bits;  conditional E-value: 3.4e-06
                 EESSTTSSHHHHHHHHHHHHTHE............................................EEEEETTTCS.SSSTTHHHHHHHHHHHHHHHT CS
         AAA   3 lyGppGtGKTllakavakelgve............................................fleisgsell.skyvgesekkirelfkeakek 56 
                 ++Gp G+GKT l+  ++ el ++                                            f+e  g  l+      +s +k+ +l++++ ++
  EEA22900.1 380 ICGPMGCGKTVLMTFLVDELTRQstyqlptpkilsyycrdnetgetiyilstlilsllqhlpglkkpFYEWYGEALVsGTNPAASTSKMGALMQKLLKS 478
                 78*****************96443334444444455555555555555555555555555555555555555555553336666666777777665333 PP

                 S.TSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTTS CS
         AAA  57 a.kpsilfiDEidalaksrsgseseeeervvnqLlteldgvkkk 99 
                   +p  ++iD +d+  +++           +  Ll +l++  ++
  EEA22900.1 479 VdRPIFILIDGLDECDSKS-----------QRSLLDFLKRSARD 511
                 3479999999999998887...........66666666665555 PP

  == domain 4  score: -3.4 bits;  conditional E-value: 7.2
                 SSTTHH.HHHHHHHHHHHHHTSTSEEEEEET CS
         AAA  37 kyvges.ekkirelfkeakekakpsilfiDE 66 
                 +++g+s ++ + ++++    ++   ilf+D+
  EEA22900.1 899 NFFGDSvMRAVDQVLQWGDVSR-LGILFLDD 928
                 4555541566788888877776.89999996 PP

>> KAP_NTPase  KAP family P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.0   0.0      0.25     4e+02      27      47 ..     382     402 ..     376     429 .. 0.86
   2 !   17.2   0.0   1.4e-06    0.0023     156     210 ..     464     519 ..     456     525 .. 0.80

  Alignments for each domain:
  == domain 1  score: 0.0 bits;  conditional E-value: 0.25
  KAP_NTPase  27 gkWGsGKssllnkledelkef 47 
                 g+ G+GK+ l ++l del  +
  EEA22900.1 382 GPMGCGKTVLMTFLVDELTRQ 402
                 666*************99876 PP

  == domain 2  score: 17.2 bits;  conditional E-value: 1.4e-06
  KAP_NTPase 156 eveelladmektLdalqkrlVvviDdLDrceteevlqlleavkllfsl.kpvvfil 210
                 + +++ a m+k L+  +++++++iD+LD c+++  ++ll+ +k  ++  ++ ++il
  EEA22900.1 464 STSKMGALMQKLLKSVDRPIFILIDGLDECDSKSQRSLLDFLKRSARDtPGLKSIL 519
                 556666779999999*************************9987654445555555 PP

>> ATPase_2  ATPase domain predominantly from Archaea
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   1.2e-05     0.019      17     143 ..     372     503 ..     364     515 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.2e-05
    ATPase_2  17 repneiyfiYGpegsGKtaLlkeiienledkdkyviyyialreesiskldefieeeeekkklekal...........giavpkaeleeilk.eksklvf 103
                 +  ++ + i Gp g+GKt L+  ++ +l     +  y  +  ++ + + ++   e+ e  ++  +l           ++++ +  +e++++ ++ +  +
  EEA22900.1 372 TPGSRQLAICGPMGCGKTVLMTFLVDELTR---QSTYQLPTPKILSYYCRDN--ETGETIYILSTLilsllqhlpglKKPFYEWYGEALVSgTNPAAST 465
                 5555667799*****************966...6689999999999999999..999999998888899999999998999999999998877777788 PP

    ATPase_2 104 kaielllekikkkgkk.iiiiiDelqklidlglngaellvk 143
                 +++ +l++k+ k+  + i i+iD l +     ++++++l++
  EEA22900.1 466 SKMGALMQKLLKSVDRpIFILIDGLDECD---SKSQRSLLD 503
                 89999999998888886779999988777...566666665 PP

>> TsaE  Threonylcarbamoyl adenosine biosynthesis protein TsaE
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.0   3.1e-05      0.05      20      63 ..     376     420 ..     357     430 .. 0.83

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 3.1e-05
                 EEEEEEESTTSSHHHHHHHHHHHTT--.----TTTTSEEEEEE.. CS
        TsaE  20 dvilLeGdLGaGKTtlvrglakalgve.evkSPTFtlveeYelek 63 
                 + +++ G++G+GKT+l+  l+ +l  + + + PT ++++ Y  ++
  EEA22900.1 376 RQLAICGPMGCGKTVLMTFLVDELTRQsTYQLPTPKILSYYCRDN 420
                 458999******************999999****99999996654 PP

>> RNA_helicase  RNA helicase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   7.2e-05      0.12       2      27 ..     379     408 ..     378     428 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 7.2e-05
  RNA_helicase   2 wlyGpsgeGKStlakeLakallkkl....k 27 
                    ++Gp g+GK++l++ L+++l++++     
    EEA22900.1 379 AICGPMGCGKTVLMTFLVDELTRQStyqlP 408
                   589******************987744443 PP

>> Cir_Bir_Yir  Plasmodium variant antigen protein Cir/Yir/Bir
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.1      0.14   2.4e+02     140     227 ..     204     296 ..     193     337 .. 0.75
   2 ?    8.5   0.0   0.00078       1.3       7      57 ..     391     441 ..     388     449 .. 0.91

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.14
  Cir_Bir_Yir 140 diskfYdafklLCnmyteldekksnckkylekaneFvekYkelnndsnitkd.ssynqvLstLsndYnnlkkkckke.kk...kipslpeikk 227
                  ++++  ++  +L ++ te+ +k ++ ++ + + +++    ++ n ++  t   s y+++L   +  ++ l kk  k  ++     +slp+i  
   EEA22900.1 204 IVKNVTEIIISLAEVKTEFAAKIKDMHERISYIDDCDTLGQKTNGQNIHTALvSVYKKLLEFYQVAFKTLTKKGVKLiTSmvrANSSLPTIAV 296
                  567778888999999999999999999999999999999999987774444349999999999999999998843333223444457777764 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.00078
  Cir_Bir_Yir   7 lrkllpdelnksgeykfkdeeklkkycpnkkcdtdldkinagclwLleqff 57 
                  l ++l+del+ +++y++ + + l+ yc +++  + +  ++  +l Ll+++ 
   EEA22900.1 391 LMTFLVDELTRQSTYQLPTPKILSYYCRDNETGETIYILSTLILSLLQHLP 441
                  56899******************************************9875 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0       8.5   1.4e+04      49      67 ..      52      71 ..      19     106 .. 0.59
   2 ?   -1.9   0.0       2.7   4.5e+03      51      80 ..     220     275 ..     200     334 .. 0.58
   3 ?   10.3   0.0   0.00047      0.76      12      38 ..     376     402 ..     368     421 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 8.5
                GGG.B-HHHCCHCEEEE-SS CS
                xxx.xxxxxxxxxxxxxxxx RF
    ABC_tran 49 lke.qeleslrkeigvlpqe 67
                ++  q+++ + ++i +l+q 
  EEA22900.1 52 TSAsQQHTTSTSSILCLTQA 71
                22235555555555555555 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 2.7
                 G...B-HHHCCHCEEEE-SS--S-TTSBHHHH........................H CS
                 x...xxxxxxxxxxxxxxxxxxxxxxxxxxxx........................x RF
    ABC_tran  51 e...qeleslrkeigvlpqepqlfpeltvren........................e 80 
                 +    +++ ++++i+++   ++l +++ +++n                        +
  EEA22900.1 220 TefaAKIKDMHERISYIDDCDTLGQKT-NGQNihtalvsvykkllefyqvafktltK 275
                 344457778888888888888887777.67776766666665555555555554441 PP

  == domain 3  score: 10.3 bits;  conditional E-value: 0.00047
                 SEEEEEESTTSSHHHHHHHHTTSS--S CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  12 ekvaivGenGaGKStLlkllagllkpt 38 
                 + +ai G+ G+GK+ L+  l  +l+ +
  EEA22900.1 376 RQLAICGPMGCGKTVLMTFLVDELTRQ 402
                 579***************999887765 PP

>> Rad17  Rad17 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00019       0.3      46      72 ..     376     402 ..     362     431 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00019
       Rad17  46 riLLisGPsGCgkstvvkvLskelgik 72 
                 r L i+GP GCgk+  +  L  el+ +
  EEA22900.1 376 RQLAICGPMGCGKTVLMTFLVDELTRQ 402
                 5689***********999999888766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1015 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       757  (0.0422221); expected 358.6 (0.02)
Passed bias filter:                      598  (0.0333538); expected 358.6 (0.02)
Passed Vit filter:                        73  (0.00407162); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.83u 0.30s 00:00:01.12 Elapsed: 00:00:00.47
# Mc/sec: 6428.09
//
Query:       EEA22901.1  [L=350]
Description: hypothetical protein PMAA_095060 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (350 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       343  (0.019131); expected 358.6 (0.02)
Passed bias filter:                      262  (0.0146132); expected 358.6 (0.02)
Passed Vit filter:                         9  (0.00050198); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.45u 0.26s 00:00:00.71 Elapsed: 00:00:00.41
# Mc/sec: 2559.42
//
Query:       EEA22902.1  [L=257]
Description: hypothetical protein PMAA_095070 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.7e-13   49.4   0.0    6.2e-13   49.1   0.0    1.2  1  NAD_binding_10  NAD(P)H-binding
      1e-08   34.9   0.0    1.3e-08   34.6   0.0    1.1  1  Epimerase       NAD dependent epimerase/dehydratase family
    0.00012   21.6   0.0    0.00016   21.2   0.0    1.2  1  GDP_Man_Dehyd   GDP-mannose 4,6 dehydratase
    0.00035   20.2   0.2    0.00049   19.7   0.2    1.3  1  NmrA            NmrA-like family
    0.00099   18.3   0.1     0.0013   17.9   0.1    1.1  1  RmlD_sub_bind   RmlD substrate binding domain
     0.0014   18.9   0.0     0.0019   18.4   0.0    1.2  1  TrkA_N          TrkA-N domain
  ------ inclusion threshold ------
      0.013   15.9   0.0       0.02   15.3   0.0    1.3  1  Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domai
      0.052   13.7   0.0      0.083   13.0   0.0    1.4  1  DapB_N          Dihydrodipicolinate reductase, N-terminus
       0.14   11.6   0.1        0.2   11.1   0.1    1.2  1  CbiJ            Precorrin-6x reductase CbiJ/CobK


Domain annotation for each model (and alignments):
>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.1   0.0   3.1e-16   6.2e-13       1     109 [.       7     129 ..       7     175 .. 0.70

  Alignments for each domain:
  == domain 1  score: 49.1 bits;  conditional E-value: 3.1e-16
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCHHHHCTTTCE.EEE--TT-CCHHHHHH..TT-SEEEES---TCC....HHHH..........H CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpeklaeleaeegle.vvegdvtdvedlaeal..kgadaVvsalggggk....deeg..........a 78 
                     G tG+vG++l+  l+a+ +h+v+a+vR+p+kl+  e +++l+ +v g++td++++++a+  +++daVv a g  +        +          +
      EEA22902.1   7 GVTGNVGSRLLPALIAH-NHTVVAFVRSPSKLS-TETKSKLDsTVIGSATDSAAIKAAIlnNNCDAVVNASGIAAPtsfhS--AgefpaifaavV 97 
                     78***************.6*************9.566677752688*************7779*******96665544430..145566633334 PP

                     HHHHHHHHHCT..--EEEEEEETTTTSGCGCHH CS
  NAD_binding_10  79 knivdaakeag..vkRfvlvsaigvgdevpgef 109
                     k++++a +e g    R  l+s++gv + +p++ 
      EEA22902.1  98 KATAEAGRERGkaPIRCWLMSGFGVLE-APKKP 129
                     444455444442234677888888884.44443 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.6   0.0   6.4e-12   1.3e-08       1      77 [.       3      80 ..       3     120 .. 0.88

  Alignments for each domain:
  == domain 1  score: 34.6 bits;  conditional E-value: 6.4e-12
                EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC.EEEE--TT-HHHHHHHHHHHT-SEEEE--S---H CS
   Epimerase  1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl.elveldltdrsalerlfkeeqpdavihlAavggv 77
                +l++G+tG +Gs l+ al +++++v+++ r +s+  t+ + +l + v +  td++a+++++ ++++dav+++ +++ +
  EEA22902.1  3 VLLLGVTGNVGSRLLPALIAHNHTVVAFVRSPSKLSTETKSKLdSTVIGSATDSAAIKAAILNNNCDAVVNASGIAAP 80
                6899***************************9999999999999****************************776554 PP

>> GDP_Man_Dehyd  GDP-mannose 4,6 dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.2   0.0     8e-08   0.00016       2      83 ..       5      75 ..       4     101 .. 0.84

  Alignments for each domain:
  == domain 1  score: 21.2 bits;  conditional E-value: 8e-08
                   EETTTSHHHHHHHHHHHHCT-CCEEEEEEESS-TTHHHHHCTTT...TTGCCEEEEE--TT-HHHHHHHHHHHT-SEEEE-- CS
  GDP_Man_Dehyd  2 iTGiaGfiGsylaelLlekgyevhgivrrsssfntgriehlakdpkeeleenlklhkgDltDssslerllaevqpdevynLA 83
                     G++G +Gs l+  L++ +++v+ +vr  s+++t++ ++l +            + g  tDs++++ ++ + ++d+v+n  
     EEA22902.1  5 LLGVTGNVGSRLLPALIAHNHTVVAFVRSPSKLSTETKSKLDS-----------TVIGSATDSAAIKAAILNNNCDAVVNAS 75
                   67***********************************999964...........488**********************933 PP

>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.2   2.5e-07   0.00049       1      62 [.       3      63 ..       3     106 .. 0.81

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 2.5e-07
                EEESSTTSHHHHHHHHHHHHHT-EEEEEES-S-SHHHHHHHHSTTEEEES-TT-HHHHHHHH CS
        NmrA  1 IlviGaTGrqGksvvrallkaghkvralvRdtkselakslkeaGvelvkgdlddkeslveal 62
                +l +G TG+ G+ +  al++++h+v a vR +++   ++ ++    +v g++ d + +++a+
  EEA22902.1  3 VLLLGVTGNVGSRLLPALIAHNHTVVAFVRSPSKLSTETKSK-LDSTVIGSATDSAAIKAAI 63
                6889***************************97766555555.5556668888889998887 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.9   0.1   6.3e-07    0.0013       1      60 [.       1      76 [.       1     110 [. 0.85

  Alignments for each domain:
  == domain 1  score: 17.9 bits;  conditional E-value: 6.3e-07
                   EEEEEESTTSHHHHHHHHHCTTTSEEEEEE-TT................T--TTSHHHHHHHHHHH--SEEEE--- CS
  RmlD_sub_bind  1 mkilvtGanGqlGseLakqlaeeglevlaltre................eldltdaeavaellkeakpdvvvnaAA 60
                   mk+l++G +G +Gs L  +l ++++ v+a+ r+                    td++a+++++ ++++d+vvna  
     EEA22902.1  1 MKVLLLGVTGNVGSRLLPALIAHNHTVVAFVRSpsklstetkskldstvIGSATDSAAIKAAILNNNCDAVVNASG 76
                   89****************************9999*********888877777899******************853 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.0   9.6e-07    0.0019       6      69 ..       9      74 ..       3      97 .. 0.86

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 9.6e-07
                -SHHHHHHHHHHHH.TTEEEEEEESSHHHHHHHHHTTSE.EEES-TTSHHHHHHTTGG.GESEEEE- CS
      TrkA_N  6 lGrvGrslaeeLse.ggkdvvvidkdeerveelreegle.vvvgdatdeevLeeagie.kadaviaa 69
                 G+vG++l+  L + ++  vv+  ++++++ + ++ +l+ +v+g+atd +++++a ++ ++dav+ a
  EEA22902.1  9 TGNVGSRLLPALIAhNH-TVVAFVRSPSKLSTETKSKLDsTVIGSATDSAAIKAAILNnNCDAVVNA 74
                69************555.7***********9999888666***************875268888766 PP

>> Semialdhyde_dh  Semialdehyde dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.3   0.0     1e-05      0.02       1      73 [.       2      74 ..       2      92 .. 0.67

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 1e-05
                    EEEEETTTSHHHHHHHHHHHCTSSEEEEEEEESTTTTTSBHHHHSGGGTTTECEBEEEGGGGGC.TT-SEEEE- CS
  Semialdhyde_dh  1 kvaivGatGyvGqellrlLeehpevelvvllsssrsaGkklaeavkaleegkdlkvedvdeeel.kevdivfla 73
                    kv ++G tG+vG++ll  L  h +  ++++ s s+   ++ +++  ++  g+     ++++++l +++d v+ a
      EEA22902.1  2 KVLLLGVTGNVGSRLLPALIAHNHTVVAFVRSPSK-LSTETKSKLDSTVIGSATDSAAIKAAILnNNCDAVVNA 74
                    799********************999988877777.22222222222233333333334445556677777766 PP

>> DapB_N  Dihydrodipicolinate reductase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   4.2e-05     0.083       1      57 [.       1      54 [.       1      89 [. 0.60

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 4.2e-05
                EEEEEETTTSHHHHHHHHHHHHSTTEEEEEEEETTCSTTTTTBHHHHSSSS--S-BE CS
      DapB_N  1 ikvavvGasGrmGkevvkaveeaedlelvaavdrkeselegkdagellglgklgvav 57
                +kv+++G++G +G++++ a+ +  ++++va v +++ +l+ +  ++ l+++ +g a+
  EEA22902.1  1 MKVLLLGVTGNVGSRLLPALIA-HNHTVVAFVRSPS-KLSTETKSK-LDSTVIGSAT 54
                89*******************9.5566666666554.444433332.2222333332 PP

>> CbiJ  Precorrin-6x reductase CbiJ/CobK
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.1    0.0001       0.2       1      71 [.       2      75 ..       2      76 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.0001
                -EEEE-SSHH.HHHHHHHHHHTT--EEEEE---SSS----S...S-EEES--S.HHHHHHHHHHHT--EEEE-S CS
        CbiJ  1 rililgGTse.arelaeaLaeagievvvsvateygaellpe.kklevrvgrlg.eeglaellreekidlvvDAT 71
                ++l+lg T++ + +l+ aL +++++vv+ v +  + +   + k  ++++g  + ++++++ + +++ d+vv+A+
  EEA22902.1  2 KVLLLGVTGNvGSRLLPALIAHNHTVVAFVRSPSKLSTETKsKLDSTVIGSATdSAAIKAAILNNNCDAVVNAS 75
                5899999999899*****************999998888876777788888878******************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (257 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       431  (0.0240393); expected 358.6 (0.02)
Passed bias filter:                      383  (0.021362); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.45u 0.22s 00:00:00.67 Elapsed: 00:00:00.38
# Mc/sec: 2020.72
//
Query:       EEA22903.1  [L=266]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.2e-10   42.1   0.4    1.8e-10   41.6   0.4    1.2  1  Hemerythrin  Hemerythrin HHE cation binding domain


Domain annotation for each model (and alignments):
>> Hemerythrin  Hemerythrin HHE cation binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.6   0.4   9.9e-15   1.8e-10      10     125 ..      47     164 ..      39     169 .. 0.85

  Alignments for each domain:
  == domain 1  score: 41.6 bits;  conditional E-value: 9.9e-15
                  HHHHHHHHHHHHHHHHHHHHHCCCHCCHHHHHH.HHHHH..HHHHHHHHHHHCHHHHH.CCC.HHHHHHHHHHHHHHHHHHHHHHHHCHTCGGSTCHH CS
  Hemerythrin  10 Hralrallerlraladaaaevhgalrklaelld.elvde..leaHhaaEEellfPlledrpggravldvlereHdeirelleelrellkgleepsaaa 104
                  H al++ l+ +     ++      +++l+++++ +l+++  l++Hh+ EEe +fP++e+++g ++ ld+  +eH  ++e l+e+  +l++le + ++a
   EEA22903.1  47 HNALLRGLNGIYIQGPNIQ-----PADLRDFIGySLCWYsaLHEHHTSEEEQFFPEIEEAVGEKGLLDRNVEEHKSFHEGLDEFSNYLESLE-GKESA 138
                  6666666666655555554.....88899999999999999***************************************************.77777 PP

                  HHH.....HHHHHHHHHHHHHHHHHH CS
  Hemerythrin 105 fae.....lleeladllreHiakEes 125
                  f+       ++ +a +l +H++ E +
   EEA22903.1 139 FDAvhlnsIIDSFAPALNHHLESELQ 164
                  777888999999999999**999855 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (266 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       441  (0.024597); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.41u 0.27s 00:00:00.68 Elapsed: 00:00:00.40
# Mc/sec: 2009.45
//
Query:       EEA22904.1  [L=476]
Description: hypothetical protein PMAA_095090 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
  ------ inclusion threshold ------
        2.1    7.1   5.6        3.9    6.2   5.6    1.4  1  ALMT        Aluminium activated malate transporter


Domain annotation for each model (and alignments):
>> ALMT  Aluminium activated malate transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.2   5.6   0.00022       3.9     305     411 ..     137     242 ..     124     277 .. 0.56

  Alignments for each domain:
  == domain 1  score: 6.2 bits;  conditional E-value: 0.00022
        ALMT 305 esakvlrelaesvkkmkklskveellkevkvaaeeLqskl.dskskLlvnsekweaakkkekaeeveekkeeekeseskkeeaeaveeaeseseksllk 402
                 e+   lre +   ++++ +  +ee l + ++ +++L+ ++  s+ +L++   + + +++k+k   ++  k+++ke ++++++a+avee++ + + ++ +
  EEA22904.1 137 EQRLTLREYKICQRQKEIKD-TEEALLSRQKTLDDLERRIqSSEGELQLRQRRLDLQEQKAKDR-KQALKARQKELDEREQRAKAVEEEARRMHLKQEE 233
                 55555666555444444444.58899999999********556678999988866555555444.4444444444444444444444444333333333 PP

        ALMT 403 eskrslkls 411
                 ++ ++  ++
  EEA22904.1 234 TKIQRRVVT 242
                 322222222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (476 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2182  (0.121702); expected 358.6 (0.02)
Passed bias filter:                      559  (0.0311785); expected 358.6 (0.02)
Passed Vit filter:                        83  (0.00462937); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.74u 0.29s 00:00:01.03 Elapsed: 00:00:00.47
# Mc/sec: 3039.91
//
Query:       EEA22905.1  [L=292]
Description: fumarylacetoacetate hydrolase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.1e-55  186.8   0.0    5.3e-55  186.5   0.0    1.1  1  FAA_hydrolase    Fumarylacetoacetate (FAA) hydrolase family
  ------ inclusion threshold ------
      0.097   13.2   0.0       0.16   12.5   0.0    1.3  1  Tnp_P_element_C  87kDa Transposase


Domain annotation for each model (and alignments):
>> FAA_hydrolase  Fumarylacetoacetate (FAA) hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  186.5   0.0   5.9e-59   5.3e-55       2     216 ..      80     288 ..      79     290 .. 0.94

  Alignments for each domain:
  == domain 1  score: 186.5 bits;  conditional E-value: 5.9e-59
                    EEEEEEE--SHHHHHTTT.-SS-EEEEEEGGGE.EETTE..EE-.TTSSSS-EE.........EEEEEEEESS-B--T--HHHHHTTEEEEEEEEE CS
  FAA_hydrolase   2 ivcdglnyaehvreagkaaeeppdrhiplepvfflkrasslvgp.gdpirrPagsek...ldyEvELavvigkplrevlsveeAedaiaGytllnD 93 
                    i c+glny++h++e++    + pd      p++flk++++l  p  +p ++P++++k    dyE ELav+igk +++v s e+A d+++Gyt +nD
     EEA22905.1  80 IRCIGLNYVSHAKEMN---LAIPD-----LPTVFLKPSTALGNPwPEPCLLPKITQKdntGDYESELAVIIGKTAKNV-SQEDALDYVLGYTTAND 166
                    67************96...67888.....688*********9883579******8877779*****************.9**************** PP

                    EE-SBGGG---.HHHHHHTGGGEEEEEE-B--B-.STT---SS-EEEEEETTEEEEEEEGGGTTTSHHHHHHHHHHHH-B-TT-EEEEEES..... CS
  FAA_hydrolase  94 vsaRdlqaeekaplgwflgksfdtftpiGpwivtpdeledpedlelrlrvngeevqdsntkdmifspaeliahlsagltLepGdliltGTpsgvg. 188
                    vs R  q+++    +w+ +k+fd+++p+Gp++ + + ++dp++l+++ ++ng++vq+  + dmif++++li+ ls+g+tL++G++i+tGTp+gvg 
     EEA22905.1 167 VSSRTSQTNQS---QWCFSKGFDGACPLGPVVASTSIIPDPAKLKIKGSLNGNVVQSCGLTDMIFTVPQLISFLSQGTTLPAGTVIITGTPPGVGa 259
                    **********9...********************************************************************************96 PP

                    ...S--EE--TT-EEEEEE.TTTEEEEEE CS
  FAA_hydrolase 189 aeeeslkflkdgDevevei.eglGelrnr 216
                    a++ s++f+k+gDe +v++   +G+l ++
     EEA22905.1 260 AKKPSPQFIKEGDEFRVSLePHIGTLITQ 288
                    78999**************7569988765 PP

>> Tnp_P_element_C  87kDa Transposase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   1.8e-05      0.16      47      86 ..     124     162 ..     110     175 .. 0.71

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 1.8e-05
  Tnp_P_element_C  47 kadeeeedlsdeeelssnsdsaieldeqeeDgleYivGyv 86 
                      k+++++++   e+el+  + + +  +  +eD+l+Y++Gy+
       EEA22905.1 124 KITQKDNTGDYESELAVIIGK-TAKNVSQEDALDYVLGYT 162
                      444444443345555555555.555889***********7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (292 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       296  (0.0165096); expected 358.6 (0.02)
Passed bias filter:                      276  (0.0153941); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.35s 00:00:00.83 Elapsed: 00:00:00.52
# Mc/sec: 1680.65
//
Query:       EEA22906.1  [L=121]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
  ------ inclusion threshold ------
      0.012   15.6   0.0       0.02   14.9   0.0    1.3  1  B12-binding  B12 binding domain


Domain annotation for each model (and alignments):
>> B12-binding  B12 binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.9   0.0   1.1e-06      0.02      12      84 ..      18      90 ..      10      92 .. 0.77

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.1e-06
  B12-binding 12 lhplGlavlaaalrd..agfeVqllganvenedivaairaekpdvvglSalltsqleavkelvellkrirprvkv 84
                 +++++++++ + +++  + + +++++ + + e+++ ++ +++pdv+     + ++ e+ + + e +++irp++k+
   EEA22906.1 18 APERAKRLIGRLIEAlkDHYTIIHVDNCETIEEVEPKVTEHQPDVLFCA--SMWTAEQSAVIFETARKIRPGIKT 90
                 5566666666666664225677788888888*************98774..689999999999999999999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (121 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       452  (0.0252106); expected 358.6 (0.02)
Passed bias filter:                      422  (0.0235373); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.28s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 860.46
//
Query:       EEA22907.1  [L=313]
Description: valacyclovir hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.2e-18   66.9   0.0    1.9e-16   60.5   0.0    2.2  1  Abhydrolase_1    alpha/beta hydrolase fold
    3.6e-15   57.2   0.0    4.6e-15   56.8   0.0    1.1  1  Abhydrolase_6    Alpha/beta hydrolase family
    7.7e-09   35.2   0.0    1.3e-08   34.5   0.0    1.3  1  Hydrolase_4      Serine aminopeptidase, S33
    2.2e-05   24.7   0.0    3.5e-05   24.0   0.0    1.3  1  Thioesterase     Thioesterase domain
    0.00023   21.1   0.0    0.00037   20.4   0.0    1.3  1  Abhydrolase_3    alpha/beta hydrolase fold
    0.00033   20.1   0.0       0.12   11.7   0.0    2.2  2  DUF915           Alpha/beta hydrolase of unknown function (DU
    0.00059   19.4   0.0    0.00095   18.7   0.0    1.3  1  DUF676           Putative serine esterase (DUF676)
     0.0007   19.4   0.6       0.15   11.8   0.6    2.2  1  PGAP1            PGAP1-like protein
      0.001   18.8   0.0     0.0013   18.4   0.0    1.3  1  Esterase         Putative esterase
     0.0045   15.9   0.1      0.013   14.4   0.2    1.8  2  Chlorophyllase2  Chlorophyllase enzyme
     0.0045   16.9   0.0     0.0058   16.5   0.0    1.2  1  Palm_thioest     Palmitoyl protein thioesterase
  ------ inclusion threshold ------
      0.018   14.9   0.0      0.029   14.2   0.0    1.4  1  Lipase_3         Lipase (class 3)
      0.044   12.9   0.0       0.72    8.9   0.0    2.0  2  DUF2048          Abhydrolase domain containing 18
      0.091   11.8   0.0        0.2   10.7   0.0    1.5  1  Chlorophyllase   Chlorophyllase
       0.13   11.0   0.0       0.23   10.1   0.0    1.6  1  Ndr              Ndr family


Domain annotation for each model (and alignments):
>> Abhydrolase_1  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   60.5   0.0   1.6e-19   1.9e-16       2     257 .]      51     296 ..      50     296 .. 0.83

  Alignments for each domain:
  == domain 1  score: 60.5 bits;  conditional E-value: 1.6e-19
                    EEEEE-STTTCGGGGTTGHHHHHHHHT.TSEEEEEEETTSTTSSSTTTGB.CHHSHHHHHHHHHHHHHHCTTSSEEEEEETHHHHHHHHHHHHHGG CS
  Abhydrolase_1   2 vlvilhGlpgssdvwaerglapaLakd.gfdvillDlrGvgySspapacinddygtasvaddldrildalgddkltlvGhSmGGmialayaaeype 96 
                    ++v+ hG+ g+  + +   + +aLa+d   d++++Dlr++g S+ ap+   ++y+   +a+d+  +  ++ ++k +l+GhSmG   a+ +a++ pe
     EEA22907.1  51 PIVFMHGFMGNKMNNRS--ISKALARDlNRDIYIVDLRNHGDSPHAPE---HTYTH--LAEDVSDFIKQHRLGKAALIGHSMGAKAAMVLALQSPE 139
                    89**********99999..****************************9...99998..************************************** PP

                    GEEEEEEESECSSCCHHHHHHHHHHHHHHCHHCHHHHHHHHHHHHHHHHCCSCHHHHHHHHHHHHHH...HCHHHCCHH.HHHHHCHHHHHHHHHH CS
  Abhydrolase_1  97 rVkalvllgaidpaaslieaqrqqaksfpdffdgyaadcarnpagplladelaaleqrhrlvdalkf...pdkskrfps.sgsdnasslatgalks 188
                       al+ ++  + +a+l++    ++k++ +  +  + +  +    +    ++ a++q++ l++ + +   ++k+ +f+   +   ++ + + +  +
     EEA22907.1 140 TATALIPVDNAPVSAMLGSPFNDYVKGMKEISEARVTKQSEADKILAKYEPSVAIRQFL-LTNLIRDpdnNNKTLKFRVpLDTLGSNLGEMADFPW 234
                    *******9998999999999999999999999999999999999999999999999985.455554466655555555533333333333333333 PP

                    HHHHHHCCHHHHHHHHHCTHHHHSEEEEEEETTCSSSCHHHHHHHHHCHTSEEEEEEETCSSSHHHHSH CS
  Abhydrolase_1 189 ieqwpttdsaklllrlrelknvlaptlvisgtsDplvppkaledlaqllpkkrlvvisdagHlaflegp 257
                    +   ++ ++++ l  + +      ptl++ g + ++v +k     ++ +p+  ++v  dagH+++ e+p
     EEA22907.1 235 KFDRENAANNADLPTYTG------PTLIVRGLQSKYVGEKRVPAVKHFFPN-AEIVGIDAGHWVISEKP 296
                    333444445556667777......***************************.***********998875 PP

>> Abhydrolase_6  Alpha/beta hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.8   0.0   3.9e-18   4.6e-15       1     219 [.      52     301 ..      52     302 .. 0.52

  Alignments for each domain:
  == domain 1  score: 56.8 bits;  conditional E-value: 3.9e-18
                    EEEE--GC.....G....C.HHHHHHHHCCT....CEEEEE--TTST.S-GGCS--HHH.CHHHHHHHCCTT..TTSEEEEEETCHHH....HHHH CS
  Abhydrolase_6   1 vlllHGagssassW....l.vapLaallaag....vhvlapDlpGhG.rsdpppldled.ladlaalldelaagggpvvlvGHSlGGa....lala 81 
                    ++++HG       +       +++ ++la++    +  +++Dl++hG +++ p ++++  ++d+++++   +   g++ l+GHS+G+     lal+
     EEA22907.1  52 IVFMHG-------FmgnkMnNRSISKALARDlnrdI--YIVDLRNHGdSPHAPEHTYTHlAEDVSDFIKQHR--LGKAALIGHSMGAKaamvLALQ 136
                    8*****.......76654245566555555555458..********94446666888884566699888886..99**********7522234444 PP

                    HHHCC....EEEEES-..----TTT................S----TTHHHHHHTT-CCCCHCCH........S-HSCCCCHHH...CCCCHCHCC CS
  Abhydrolase_6  82 aapla..lvvgvlldppptalpagl................laaalelllallallrllawlsre........plprlfladed...adaawrarl 148
                       ++       +l p   ++ a+                     +++ ++  a    +  l+++        +l   +++d+d   +   +r++l
     EEA22907.1 137 ---SPetA---TALIP---VDNAPVsamlgspfndyvkgmkEISEARVTKQSEA----DKILAKYepsvairqFLLTNLIRDPDnnnKTLKFRVPL 219
                    ...22220...44444...33333322221111112222222222222222222....22222223443334433338888888655244444444 PP

                    CGHH....HHCCHHC......HTTCCHHTT-TTGCEEE.C......TT-CHHHHCHHCCCHSTTEEETCE...SSS-HHHHSHHHHHH CS
  Abhydrolase_6 149 arla....allaglg......llpaaawadlpvpllvl.g......geDplvprllerllaqagarlpvvlpgaGHlphleepdevae 219
                    ++l       +++++      + + a++++++ p+l++ g      ge   vp  + ++   + a++ v +  aGH++  e+p+e+ +
     EEA22907.1 220 DTLGsnlgEMADFPWkfdrenAANNADLPTYTGPTLIVrGlqskyvGEK-RVP--AVKHFF-PNAEI-VGID-AGHWVISEKPEEFRQ 301
                    4444333344443333233332236688888888888885222332333.333..223333.66666.5555.***********9976 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.5   0.0   1.1e-11   1.3e-08       7     107 ..      52     147 ..      47     215 .. 0.75

  Alignments for each domain:
  == domain 1  score: 34.5 bits;  conditional E-value: 1.1e-11
  Hydrolase_4   7 vvlvHGlaehsgryaelaeaLaaq.GfavyalDhrGhGrsegkrghvpsfddyvdDlaafvekvkeehpelplfllGhSmGGliallyllrypdkvag 103
                  +v++HG+         + +aLa+  + ++y++D r hG s+  ++  + ++++ +D++ f+++    h+  +  l+GhSmG+  a+ ++l+ p+  ++
   EEA22907.1  52 IVFMHGFMGNKMNNRSISKALARDlNRDIYIVDLRNHGDSP--HAPEHTYTHLAEDVSDFIKQ----HRLGKAALIGHSMGAKAAMVLALQSPETATA 143
                  899999999999999999999975499*************5..4446899**********855....5566899********************8888 PP

  Hydrolase_4 104 lils 107
                  li +
   EEA22907.1 144 LIPV 147
                  8854 PP

>> Thioesterase  Thioesterase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.0   0.0   2.9e-08   3.5e-05       5      86 ..      54     136 ..      50     152 .. 0.81

  Alignments for each domain:
  == domain 1  score: 24.0 bits;  conditional E-value: 2.9e-08
                   EE--TTCCSGGGHHHHHHCTTC.EEEEEEECSTTST.SHHHCTTCHHHHHHHHHHHHHHH-SSSSEEEEEETHHHHHHHHHHHH CS
  Thioesterase   5 lfppagGsasvfrslasklsdp.vvevlavqlpgre.rdepplesieelaaeyaealrqiqpegPyalfGhSlGgllAfevArq 86 
                    +++  G+    rs++++l ++   +++ v l+ ++ ++++p ++ + la+ + + ++q+   g  al+GhS+G+  A+ +A q
    EEA22907.1  54 FMHGFMGNKMNNRSISKALARDlNRDIYIVDLRNHGdSPHAPEHTYTHLAEDVSDFIKQHRL-GKAALIGHSMGAKAAMVLALQ 136
                   55666666666666666666666666888888888889*******************99765.589***************987 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   0.0   3.1e-07   0.00037       2     146 ..      53     199 ..      52     218 .. 0.74

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 3.1e-07
                    EEE--STTTS--TTTTHHHHHHHHHHHTSEEEEEE--......-TTTS-TTHHHHHHHHHHHHHHHTHHHHTETTCEEEEEEETHHHHHHHHHHHH CS
  Abhydrolase_3   2 vyfHGGGfvlgsldthdalcrelakelgavvvsvdYr......lAPehpfPaavedalaalrwlaeqawelgadpsrivlaGdSaGGnlaaavalr 91 
                    v++HG    +g+   ++++ + la++l+  ++ vd r       APeh +    ed+ + +++   +         + +l G S G++ a+++al+
     EEA22907.1  53 VFMHG---FMGNKMNNRSISKALARDLNRDIYIVDLRnhgdspHAPEHTYTHLAEDVSDFIKQ---H------RLGKAALIGHSMGAKAAMVLALQ 136
                    66665...46666778999****************9955555569999999999999998874...3......56799****************99 PP

                    HHHTT---......EEEEEEESE-SST...SSTTSHHHHHCHHTTTSSSSCHHHHHHHHHHHSS CS
  Abhydrolase_3  92 ardegepk......vagqvliyPvtdl...ertesesikkaeeladgplltraaldlfwrlylp 146
                      ++ +        ++  +l +P +d     +  se++ +++++ad ++l + +   ++r++l 
     EEA22907.1 137 SPETATALipvdnaPVSAMLGSPFNDYvkgMKEISEARVTKQSEAD-KILAKYEPSVAIRQFLL 199
                    99985444889999*********77666542333444434444455.55666666666776664 PP

>> DUF915  Alpha/beta hydrolase of unknown function (DUF915)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.3   0.0    0.0045       5.3       4      35 ..      42      73 ..      39      90 .. 0.76
   2 !   11.7   0.0    0.0001      0.12      93     164 ..     106     182 ..      90     195 .. 0.74

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0045
      DUF915  4 lksekkkeiPtifihGyggtaeslnemvkqle 35
                 +++k++  P++f+hG+ g++    ++ k+l+
  EEA22907.1 42 AQDKKRSGQPIVFMHGFMGNKMNNRSISKALA 73
                56788999***********9877766666664 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 0.0001
      DUF915  93 lseLkkkYnikkfnavGhSmGglaltsYleeyaddks..lPqlkklvt..iggpfngienndedetlaqvkkdg.pk 164
                 +s+  k+  + k+ ++GhSmG+ a+++ + +  +  +  +P  +  v+  +g+pfn+ ++  ++  +a v+k+  + 
  EEA22907.1 106 VSDFIKQHRLGKAALIGHSMGAKAAMVLALQSPETATalIPVDNAPVSamLGSPFNDYVKGMKEISEARVTKQSeAD 182
                 67788999999************999988776554332245555555444999999999988888888888865444 PP

>> DUF676  Putative serine esterase (DUF676)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   7.9e-07   0.00095       8      93 ..      52     130 ..      47     156 .. 0.82

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 7.9e-07
      DUF676   8 vVlvHGlqgnsaDlelikeqlekikeklpeekieflmsennesktfkgidvlgerlaeevlevvkkkkdknkkiSfvghSlGglia 93 
                 +V+ HG+ gn+ + ++i ++l +   +l+++   +    +n+ ++ +  +   + lae v +++k+ + +  k  ++ghS+G   a
  EEA22907.1  52 IVFMHGFMGNKMNNRSISKALAR---DLNRDI--YIVDLRNHGDSPHAPEHTYTHLAEDVSDFIKQHRLG--KAALIGHSMGAKAA 130
                 79*********************...676664..444566777777777888889***************..9*********7543 PP

>> PGAP1  PGAP1-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   0.6   0.00012      0.15       3     105 ..      48     130 ..      46     188 .. 0.60

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00012
       PGAP1   3 sGipVlFvpGnagsykqvrslAseaaeayqelrkllknqnkkeldfftvdfneelsaldG..rtlldqaeylndaIkyIlslysssekeptsviliGHS 99 
                 sG p++F++G +g+  + rs++++ a++  +             d + vd+ +     +   +t    ae + d Ik+         ++  +  liGHS
  EEA22907.1  48 SGQPIVFMHGFMGNKMNNRSISKALARDLNR-------------DIYIVDLRNHGDSPHApeHTYTHLAEDVSDFIKQ---------HRLGKAALIGHS 124
                 7999999999999999999999988333222.............2233333322222211002222223333333333.........344455666777 PP

       PGAP1 100 mGGiva 105
                 mG + a
  EEA22907.1 125 MGAKAA 130
                 765555 PP

>> Esterase  Putative esterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.0   1.1e-06    0.0013      90     138 ..      94     139 ..      43     183 .. 0.86

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 1.1e-06
                 CCCCHCHHHHTHHHHHHHHHCSEECCCEEEEEETHHHHHHHHHHHCSTT CS
    Esterase  90 gaeayetfltqeLlplldanfrtapdgravaGqSmGGlgALilalkhpd 138
                   e+  t l++ + +++++++  +    a++G+SmG+ +A++lal++p+
  EEA22907.1  94 APEHTYTHLAEDVSDFIKQHRLGK---AALIGHSMGAKAAMVLALQSPE 139
                 445555778888888887765433...67*******************8 PP

>> Chlorophyllase2  Chlorophyllase enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.4   0.2   1.1e-05     0.013      88     128 ..     114     153 ..      51     172 .. 0.83
   2 ?   -3.2   0.0       2.6   3.1e+03     146     165 ..     211     230 ..     208     236 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 1.1e-05
  Chlorophyllase2  88 dlsklalsgHSrGgktafalalgkaktslkfsaligvd..Pva 128
                       l k al gHS G+k+a+ lal++ +   +  ali vd  Pv+
       EEA22907.1 114 RLGKAALIGHSMGAKAAMVLALQSPE---TATALIPVDnaPVS 153
                      67899*******************99...66777777644554 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.6
  Chlorophyllase2 146 esfnlkmpvlviGtgLgeek 165
                      +++++++p   +G++Lge +
       EEA22907.1 211 KTLKFRVPLDTLGSNLGEMA 230
                      56677999999******976 PP

>> Palm_thioest  Palmitoyl protein thioesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0   4.9e-06    0.0058       1      84 [.      51     134 ..      51     215 .. 0.70

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 4.9e-06
  Palm_thioest   1 PvviwhGldsaesnmqklaeliekligtyvknveigesea.edrkasffgnlndqveavckklelangfhaiGfSQGglflRali 84 
                   P+v++hG+  ++ n +++ +++ ++++  +++v++ ++       ++ +++l + v++++k++    +  +iG+S G+  +  l+
    EEA22907.1  51 PIVFMHGFMGNKMNNRSISKALARDLNRDIYIVDLRNHGDsPHAPEHTYTHLAEDVSDFIKQH-RLGKAALIGHSMGAKAAMVLA 134
                   9*******555555688888888877555566664443332567788999************4.55889********98765555 PP

>> Lipase_3  Lipase (class 3)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2   0.0   2.5e-05     0.029      45      86 ..      96     137 ..      33     160 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 2.5e-05
                 S-HHHHHHHHHHHHHHHTT-EEEEEEEETHHHHHHHHHHHHH CS
    Lipase_3  45 eslreqvlkelkrllekypeysivvtGHSLGgalAlLaaldl 86 
                 e +++++ +++++ +++++  + ++ GHS+G+  A+++al+ 
  EEA22907.1  96 EHTYTHLAEDVSDFIKQHRLGKAALIGHSMGAKAAMVLALQS 137
                 57899999*****************************99875 PP

>> DUF2048  Abhydrolase domain containing 18
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0     0.066        79     170     205 ..     110     146 ..     101     193 .. 0.85
   2 ?    8.9   0.0    0.0006      0.72     295     351 ..     253     308 ..     207     309 .. 0.87

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.066
     DUF2048 170 lereGyGplgltGlSmGGhmaslaasnwpkplv.lvp 205
                 ++++  G+ +l G SmG   a + a ++p  ++ l+p
  EEA22907.1 110 IKQHRLGKAALIGHSMGAKAAMVLALQSPETATaLIP 146
                 6677789**********99999888888876542566 PP

  == domain 2  score: 8.9 bits;  conditional E-value: 0.0006
     DUF2048 295 liivvaAkdDayvpresvaslqeiwpgsevryldgGHvsayllkkklfrkaiveale 351
                    +v   + +yv ++ v  +++ +p++e+  +d+GH   +  k + fr+a+++ ++
  EEA22907.1 253 PTLIVRGLQSKYVGEKRVPAVKHFFPNAEIVGIDAGHW-VISEKPEEFRQAVIKFFR 308
                 55677788899**************************7.46689999**99998875 PP

>> Chlorophyllase  Chlorophyllase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   0.0   0.00016       0.2     119     154 ..     115     148 ..      95     157 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00016
  Chlorophyllase 119 lsklalvGhsrGGktafalalgysseltfsaliGvd 154
                     l k al+Ghs G k+a+ lal+     t +ali vd
      EEA22907.1 115 LGKAALIGHSMGAKAAMVLALQSP--ETATALIPVD 148
                     6789*****************865..5778999988 PP

>> Ndr  Ndr family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0    0.0002      0.23      81     139 ..      98     156 ..      91     309 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.0002
                 -HHHHHTTHHHHHHHHT---EEEEEETHHHHHHHHHHHHSGGGEEEEEEES---S---H CS
         Ndr  81 slddladqllavldhfklksviglGvgaGAyilarfalkhperveglvLinitskaagw 139
                 +  +la++++  +++ +l ++  +G   GA   +  al+ pe+ ++l+ ++  + +a +
  EEA22907.1  98 TYTHLAEDVSDFIKQHRLGKAALIGHSMGAKAAMVLALQSPETATALIPVDNAPVSAML 156
                 5678********************************************99888766554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (313 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       464  (0.0258799); expected 358.6 (0.02)
Passed bias filter:                      452  (0.0252106); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                        15  (0.000836633); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.54u 0.28s 00:00:00.82 Elapsed: 00:00:00.43
# Mc/sec: 2177.44
//
Query:       EEA22908.1  [L=770]
Description: paramyosin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    0.00042   20.1   2.1    0.00042   20.1   0.3    1.8  2  Collagen_mid  Bacterial collagen, middle region
  ------ inclusion threshold ------
      0.023   14.5   7.9        6.6    6.7   0.0    5.7  6  HSBP1         Heat shock factor binding protein 1


Domain annotation for each model (and alignments):
>> Collagen_mid  Bacterial collagen, middle region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.1      0.34     3e+03      72     136 ..     489     508 ..     472     526 .. 0.54
   2 !   20.1   0.3   4.7e-08   0.00042      30     139 ..     558     667 ..     539     675 .. 0.92

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.34
  Collagen_mid  72 LgtgplaplapvttpvggvvstvgqavtsagttLttalssgpvqqltqqlssaitPitstvtgtt 136
                   L                                               q+++++t++ s++++ t
    EEA22908.1 489 LQ---------------------------------------------AQATQTLTNVESNISNNT 508
                   33.............................................333333333333333333 PP

  == domain 2  score: 20.1 bits;  conditional E-value: 4.7e-08
  Collagen_mid  30 vsaGLGqlgetanpvGtTlastgnvvtelgeavssagslVsaLgtgplaplapvttpvggvvstvgqavtsagttLttalssgpvqqltqqlssait 126
                   +++ LG+l + ++ v   l+s ++ v el    ++  +  +aL ++  ++++ v + +   v+++g  ++++++++ ++ls + +++  +++ +  +
    EEA22908.1 558 LRQTLGELNKEKDRVVGELTSISGSVDELKVQAQAQKDQHTALAQSTSSQVQTVEQRLTARVKEIGDSIQHVEQKISETLSASGLEDAKSSIENFEV 654
                   6788**********************************************************************************99999999999 PP

  Collagen_mid 127 Pitstvtgttqtv 139
                    + ++v++ t ++
    EEA22908.1 655 ALQQHVESLTFQL 667
                   9999998887655 PP

>> HSBP1  Heat shock factor binding protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0      0.29   2.6e+03      23      32 ..     294     303 ..     289     305 .. 0.64
   2 ?    0.1   0.0     0.081   7.3e+02      38      50 ..     378     390 ..     355     391 .. 0.85
   3 ?   -1.3   0.0      0.23   2.1e+03      26      45 ..     524     536 ..     516     541 .. 0.64
   4 ?   -3.9   0.0       1.5   1.4e+04      25      39 ..     572     586 ..     570     591 .. 0.72
   5 ?    6.7   0.0   0.00074       6.6      16      48 ..     606     638 ..     599     641 .. 0.86
   6 ?    5.9   0.6    0.0012        11      24      40 ..     705     721 ..     703     723 .. 0.87

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.29
       HSBP1  23 dqilsriDdM 32 
                 +qi++r+D +
  EEA22908.1 294 NQIVTRLDAI 303
                 5667777654 PP

  == domain 2  score: 0.1 bits;  conditional E-value: 0.081
       HSBP1  38 dLEksiadlmtqa 50 
                 dLEk i+++ t+a
  EEA22908.1 378 DLEKAISEVKTSA 390
                 7******999876 PP

  == domain 3  score: -1.3 bits;  conditional E-value: 0.23
       HSBP1  26 lsriDdMssriDdLEksiad 45 
                 l       ++iD+ +k+ a+
  EEA22908.1 524 L-------QKIDEVQKNYAE 536
                 4.......456666666555 PP

  == domain 4  score: -3.9 bits;  conditional E-value: 1.5
       HSBP1  25 ilsriDdMssriDdL 39 
                 +++ +  +s  +D+L
  EEA22908.1 572 VVGELTSISGSVDEL 586
                 667777778888887 PP

  == domain 5  score: 6.7 bits;  conditional E-value: 0.00074
       HSBP1  16 dkFqtmsdqilsriDdMssriDdLEksiadlmt 48 
                 +  qt+++ ++ r+ +++  i   E+ i++  +
  EEA22908.1 606 SQVQTVEQRLTARVKEIGDSIQHVEQKISETLS 638
                 5679************************98765 PP

  == domain 6  score: 5.9 bits;  conditional E-value: 0.0012
       HSBP1  24 qilsriDdMssriDdLE 40 
                 +i   ++++ +riDdLE
  EEA22908.1 705 EIKMTLEELAQRIDDLE 721
                 677889**********9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (770 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2562  (0.142897); expected 358.6 (0.02)
Passed bias filter:                      509  (0.0283898); expected 358.6 (0.02)
Passed Vit filter:                        70  (0.00390429); expected 17.9 (0.001)
Passed Fwd filter:                        44  (0.00245412); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 1.47u 0.36s 00:00:01.83 Elapsed: 00:00:00.58
# Mc/sec: 3984.86
//
Query:       EEA22909.1  [L=468]
Description: AAA family ATPase Rvb2/Reptin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   9.4e-152  505.2   0.5   9.4e-152  505.2   0.5    1.3  2  TIP49            TIP49 P-loop domain
    4.4e-22   78.0   0.3    1.4e-21   76.4   0.3    1.9  1  TIP49_C          TIP49 AAA-lid domain
    7.3e-08   32.9   0.7    0.00015   22.2   0.0    2.8  3  AAA              ATPase family associated with various cellul
    8.4e-08   32.1   0.5    7.9e-05   22.4   0.0    2.4  2  RuvB_N           Holliday junction DNA helicase RuvB P-loop d
      1e-06   29.2   0.4      5e-06   27.0   0.1    2.2  2  AAA_16           AAA ATPase domain
    7.9e-06   25.4   0.4    1.6e-05   24.4   0.4    1.5  1  DnaB_C           DnaB-like helicase C terminal domain
     0.0012   18.3   0.4      0.016   14.6   0.2    2.3  2  Mg_chelatase     Magnesium chelatase, subunit ChlI
  ------ inclusion threshold ------
       0.01   15.6   0.0        5.8    6.6   0.0    2.4  2  Sigma54_activat  Sigma-54 interaction domain
      0.017   15.5   1.3       0.41   11.0   1.3    2.5  1  AAA_19           AAA domain
      0.017   15.4   0.0        3.1    8.1   0.0    2.4  2  AAA_22           AAA domain
      0.057   13.0   0.1       0.12   12.0   0.1    1.5  1  AAA_25           AAA domain
      0.063   13.3   0.1          2    8.4   0.0    2.8  2  AAA_5            AAA domain (dynein-related subfamily)
      0.066   13.4   0.0       0.14   12.3   0.0    1.6  1  AAA_33           AAA domain
      0.079   12.5   0.2       0.64    9.5   0.0    2.2  2  AAA_7            P-loop containing dynein motor region
      0.084   12.7   0.2        0.2   11.4   0.2    1.8  1  AAA_11           AAA domain
        0.1   12.7   0.0       0.21   11.7   0.0    1.5  1  TFIID-31kDa      Transcription initiation factor IID, 31kD su


Domain annotation for each model (and alignments):
>> TIP49  TIP49 P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  505.2   0.5  8.3e-155  9.4e-152       2     350 ..      20     362 ..      19     363 .. 0.98
   2 ?   -4.1   0.0         6   6.7e+03      70     106 ..     391     427 ..     385     429 .. 0.65

  Alignments for each domain:
  == domain 1  score: 505.2 bits;  conditional E-value: 8.3e-155
                 XXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49   2 islhshikgLGld.edgeaekeeeglvGqkkareaagvivelikekklaGravLlaGpsgtGktalaiaiskelgedvpfvalsgsevyslevkktevl 99 
                 i++hshi+gLG+d ++++++ +++glvGq+kar+aa+vi++++k++ +aGravL+aGp++tGkta+a++++++lg dvpf++l++sev+sl+++kte+l
  EEA22909.1  20 IAAHSHIRGLGVDpDTLQPRPSSQGLVGQEKARKAAAVILQMVKAGDIAGRAVLIAGPPSTGKTAIAMGMAQSLGPDVPFTTLASSEVFSLDMSKTEAL 118
                 89**********95568999******************************************************************************* PP

                 XXXXXXXXXXXXXX-S-EEEEEEEEEEE...-SSS-..TTS--EEEEEE-SS-EEEEEE-HHHHHHHHHHT--TT-EEEEETTT--EEE-SSS-SS--- CS
       TIP49 100 tqalrksigvrikeekevleGevveleveeaenplskekkikevkitlktakeekklklgskiaeellkekvkegDviviekesGkvkklGrsearake 198
                 tqa+rksigvrikee+e++eGevve+++   +++++     k+ k+t+kt+++e+ +++g+k+++++++e+v++gDvi i+k+sGk++klGrs ar+++
  EEA22909.1 119 TQAFRKSIGVRIKEESEIIEGEVVEIQI---DRSVT--GGNKQGKLTIKTTDMETIYDMGTKMIDSMTRERVMAGDVISIDKSSGKITKLGRSYARSRD 212
                 **************************99...67776..678999******************************************************* PP

                 ---..S--------S---S----XXXXXXXXXXXXXXXXXXXXXXXX....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49 199 fDi..ekdefvelPkGevekkkevvqevtLhdlDvanarpqdllslllqllkskkteiteklreeinkkvakyveegkaeivpGvlfiDevhmlDiecf 295
                 +D+   + +fv+ P+Ge++ +ke+v++v+Lh++Dv+n+r+q++l+l+    +++++ei++++r++in+kva+++eegkaei+pGvlfiDevhmlDiec+
  EEA22909.1 213 YDAmgPDAKFVQTPEGELQVRKEIVHTVSLHEIDVINSRSQGFLALF----SGDTGEIRSEVRDQINTKVAEWKEEGKAEIIPGVLFIDEVHMLDIECY 307
                 ***9999****************************************....************************************************ PP

                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49 296 sylnraleselaPivilatnrgiakirGtdiisphGipvDlldrlliiktekytk 350
                 sy+nrale elaPivi+a+nrgi++irGt++ sphG+p+Dlldr+ ii+t++yt+
  EEA22909.1 308 SYINRALEAELAPIVIMASNRGITRIRGTNYSSPHGLPLDLLDRVSIISTQPYTS 362
                 *****************************************************86 PP

  == domain 2  score: -4.1 bits;  conditional E-value: 6
                 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
       TIP49  70 iskelgedvpfvalsgsevyslevkktevltqalrks 106
                 i +e g     +++++s++ s + k  ev ++ +++s
  EEA22909.1 391 IGQESGLRYASNIITTSQLLSEKRKAKEVNVDDIQRS 427
                 5555555556667777777777777777777776665 PP

>> TIP49_C  TIP49 AAA-lid domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.4   0.3   1.2e-24   1.4e-21       1      66 []     368     433 ..     368     433 .. 0.99

  Alignments for each domain:
  == domain 1  score: 76.4 bits;  conditional E-value: 1.2e-24
     TIP49_C   1 IlkiRakeEgvkldeeAldlLakigtetSLRYaiqLltpasilakkrkkkevevedveeveeLFlD 66 
                 Il+iRa+eE+v+l+ +Al lL+kig e++LRYa + +t +++l++krk+kev+v+d+++ ++LF+D
  EEA22909.1 368 ILAIRAQEEEVDLSPDALALLTKIGQESGLRYASNIITTSQLLSEKRKAKEVNVDDIQRSYRLFYD 433
                 9****************************************************************9 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.2   0.0   1.3e-07   0.00015       1      49 [.      72     122 ..      72     145 .. 0.80
   2 !    8.3   0.0    0.0026       2.9      32      70 ..     264     302 ..     232     355 .. 0.71
   3 ?   -3.3   0.0       9.9   1.1e+04      65      98 ..     363     396 ..     363     412 .. 0.61

  Alignments for each domain:
  == domain 1  score: 22.2 bits;  conditional E-value: 1.3e-07
                 EEEESSTTSSHHHHHHHHHHHHT..HEEEEEETTTCSSSSTTHHHHHHHHH CS
         AAA   1 vllyGppGtGKTllakavakelg..vefleisgsellskyvgesekkirel 49 
                 vl+ Gpp tGKT++a  +a++lg  v+f ++  se++s  ++++e+ ++++
  EEA22909.1  72 VLIAGPPSTGKTAIAMGMAQSLGpdVPFTTLASSEVFSLDMSKTEALTQAF 122
                 799*******************77799999999999965555555554444 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.0026
                 TTCSSSSTTHHHHHHHHHHHHHHHTS....TSEEEEEETGGGH CS
         AAA  32 sellskyvgesekkirelfkeakeka....kpsilfiDEidal 70 
                  e++    +e  ++i+  ++e ke+      p +lfiDE++ l
  EEA22909.1 264 GEIR----SEVRDQINTKVAEWKEEGkaeiIPGVLFIDEVHML 302
                 4444....444445554444444444455578********987 PP

  == domain 3  score: -3.3 bits;  conditional E-value: 9.9
                 ETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTTT CS
         AAA  65 DEidalaksrsgseseeeervvnqLlteldgvkk 98 
                 DEi ++   r ++e+ + +  + +Llt++ +++ 
  EEA22909.1 363 DEIRQILAIRAQEEEVDLSPDALALLTKIGQESG 396
                 7888888888555555555555566666655555 PP

>> RuvB_N  Holliday junction DNA helicase RuvB P-loop domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.4   0.0   7.1e-08   7.9e-05       7      64 ..      43     100 ..      36     114 .. 0.90
   2 !    7.6   0.1    0.0026       2.9      87     118 ..     293     324 ..     288     333 .. 0.86

  Alignments for each domain:
  == domain 1  score: 22.4 bits;  conditional E-value: 7.1e-08
      RuvB_N   7 eeyigqekvkeklkifieaakkreealdhvllyGpPGlGkttlakiiakelgvklkit 64 
                 +  +gqek ++  +++++  k+ + a   vl++GpP  Gkt++a+ +a+ lg ++  t
  EEA22909.1  43 QGLVGQEKARKAAAVILQMVKAGDIAGRAVLIAGPPSTGKTAIAMGMAQSLGPDVPFT 100
                 5689**********************************************99887666 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0026
      RuvB_N  87 vlfideihrlsraveevlysamedfrldivig 118
                 vlfide+h l+ +   ++  a+e     ivi 
  EEA22909.1 293 VLFIDEVHMLDIECYSYINRALEAELAPIVIM 324
                 9*************999999*99887777775 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.0   0.1   4.4e-09     5e-06       2     107 ..      45     209 ..      44     319 .. 0.67
   2 ?   -1.1   0.0         2   2.2e+03      80     145 ..     367     425 ..     325     436 .. 0.52

  Alignments for each domain:
  == domain 1  score: 27.0 bits;  conditional E-value: 4.4e-09
      AAA_16   2 lvGReeeleqLlsalervrsgrp..elvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipy.salaqalareellrqlldeaesaeleaw 97 
                 lvG e+ +++ + +l++v++g+   ++vl+ G++ +GK++++   +++l  d  +++ +  + ++ +++   al+qa+ r+++   +++e+e  e e  
  EEA22909.1  45 LVGQEKARKAAAVILQMVKAGDIagRAVLIAGPPSTGKTAIAMGMAQSLGPDVPFTTLASSEVFSLDMSKtEALTQAF-RKSIGVRIKEESEIIEGEVV 142
                 7999************************************************55556666666633333324599999.77999999999999999988 PP

      AAA_16  98 rekleeala.........................................................a 107
                   +++++++                                                          
  EEA22909.1 143 EIQIDRSVTggnkqgkltikttdmetiydmgtkmidsmtrervmagdvisidkssgkitklgrsyaR 209
                 8888888887776666666666666666666666666665555555555555555555555555550 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 2
      AAA_16  80 ellrqlldeaesaeleawrekleealaavpelagaeasrllellkrllallsrderplvlvlDdlq 145
                 ++l+  ++e e+ +l++++ +l++ ++       ++  r +  +    +lls++++   + +Dd+q
  EEA22909.1 367 QILAIRAQE-EEVDLSPDALALLTKIG------QESGLRYASNIITTSQLLSEKRKAKEVNVDDIQ 425
                 333333333.33355555555555544......222244555555555555555555556666665 PP

>> DnaB_C  DnaB-like helicase C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4   0.4   1.4e-08   1.6e-05      18     123 ..      68     178 ..      58     196 .. 0.71

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 1.4e-08
                 TTXEEEEEEXTTSSHHHHHHHHHHHHHH....CSTSEEEEEESSSXHHHHHHHHHHHHHTXX...HHHHHHTTSXHHHHHHHHHHHHHHHHSEEEEEEX CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
      DnaB_C  18 kgdliiiAarpsmGktalalniaenaav....keklpvavfslemsaeqlvqRllsseaeid...skklrtgklkeedweklteaieelseaklfiddt 109
                  g  ++iA+ ps+Gkta+a+ +a++       ++ ++  vfsl+ms+++ +++ + +  +++   ++++ +g++ e ++++  +  +  ++ kl+i+ t
  EEA22909.1  68 AGRAVLIAGPPSTGKTAIAMGMAQSLGPdvpfTTLASSEVFSLDMSKTEALTQAFRKSIGVRikeESEIIEGEVVEIQIDRSVTGGN--KQGKLTIKTT 164
                 567799******************987523334445699**********99999998888763234566778887766666655544..6777888888 PP

                 SSXCHHHHHHHHHH CS
                 xxxxxxxxxxxxxx RF
      DnaB_C 110 paltvseirskarr 123
                    t+ ++ +k+  
  EEA22909.1 165 DMETIYDMGTKMID 178
                 88888888777644 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.6   0.2   1.4e-05     0.016       5      68 ..      45     115 ..      42     126 .. 0.74
   2 ?    0.9   0.0      0.23   2.5e+02     108     133 ..     292     317 ..     286     330 .. 0.80

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 1.4e-05
  Mg_chelatase   5 vkGqeeakra....leiaaaG...gHnlllvGppGsGKtmlakrlpsllpplseeealevakiasvagkke 68 
                   ++Gqe+a++a    l++  aG   g  +l++Gpp +GKt +a  +++ l p     +l ++++ s+  +k+
    EEA22909.1  45 LVGQEKARKAaaviLQMVKAGdiaGRAVLIAGPPSTGKTAIAMGMAQSLGPDVPFTTLASSEVFSLDMSKT 115
                   578888888722224445676333578******************99999999999999999999877333 PP

  == domain 2  score: 0.9 bits;  conditional E-value: 0.23
  Mg_chelatase 108 GvLfLDElpefkrkvlevLRePledg 133
                   GvLf+DE+  ++ +    + + le++
    EEA22909.1 292 GVLFIDEVHMLDIECYSYINRALEAE 317
                   9*******999888888887777765 PP

>> Sigma54_activat  Sigma-54 interaction domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.6   0.0    0.0052       5.8      10      45 ..      54      92 ..      45     114 .. 0.66
   2 ?    6.5   0.0    0.0053         6      94     119 ..     291     316 ..     277     323 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.6 bits;  conditional E-value: 0.0052
                     HHHHHHHHHCTSS...S-EEEECSTTSSHHHHHHHHHHH CS
  Sigma54_activat 10 elleqikkvaktd...lsvlitGesGtGKellaraihea 45
                     ++   +++v + d     vli G   tGK+ +a  + ++
       EEA22909.1 54 AAAVILQMVKAGDiagRAVLIAGPPSTGKTAIAMGMAQS 92
                     333333333333333489***************988764 PP

  == domain 2  score: 6.5 bits;  conditional E-value: 0.0053
                      TSEEEEETGGGS-HHHHHHHHHHHHH CS
  Sigma54_activat  94 gGtlfLDeigelplelQekLlrvlqe 119
                       G+lf+De++ l++e+ + + r+l+ 
       EEA22909.1 291 PGVLFIDEVHMLDIECYSYINRALEA 316
                      59*************99999998886 PP

>> AAA_19  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   1.3   0.00037      0.41       8     126 ..      67     314 ..      60     324 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00037
      AAA_19   8 lkekvllvtaGpGtGKTrvlkhivallvelggvkp.............eeillvaftgrAakelrerlaalgae......................... 68 
                 ++ + +l+ ++p tGKT + +++ + l                      e l  af +    +++e+ + +++e                         
  EEA22909.1  67 IAGRAVLIAGPPSTGKTAIAMGMAQSLGPDVPFTTlassevfsldmskTEALTQAFRKSIGVRIKEESEIIEGEvveiqidrsvtggnkqgkltikttd 165
                 667889999999999999999999888765533335555555555554444444554444555555555555558888888888888888877766666 PP

      AAA_19  69 atTiHrlal.......................................................................................... 77 
                  +Ti  +++                                                                                          
  EEA22909.1 166 METIYDMGTkmidsmtrervmagdvisidkssgkitklgrsyarsrdydamgpdakfvqtpegelqvrkeivhtvslheidvinsrsqgflalfsgdtg 264
                 666666655889999999999999999999999999999999999999999999999999999999999999999999999999999999999999998 PP

      AAA_19  78 ...ldfddlltealelleeaeeekklqeeellivDEfqdvdelqyrLlkall 126
                     ++ d+++++++  +e e + ++    +l++DE+ ++d   y+ +++ l
  EEA22909.1 265 eirSEVRDQINTKVAEWKE-EGKAEI-IPGVLFIDEVHMLDIECYSYINRAL 314
                 8884455555444444454.444444.3669**********88888777666 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.9   0.0     0.026        29       6      51 ..      70     106 ..      68     151 .. 0.76
   2 ?    8.1   0.0    0.0027       3.1      74     128 ..     262     324 ..     201     333 .. 0.76

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.026
      AAA_22   6 gilvvtGesGtGKTtllrrlleqldeeakaeeerpevvfvtlpsst 51 
                 + +++ G++ tGKT  +  ++++l         +p+v f tl+ss+
  EEA22909.1  70 RAVLIAGPPSTGKTAIAMGMAQSL---------GPDVPFTTLASSE 106
                 56899***********99999998.........6666666666665 PP

  == domain 2  score: 8.1 bits;  conditional E-value: 0.0027
      AAA_22  74 sseellealeqalrarav...........ielliiDEaqhlrseealeeLrsllnlsrkgvqliLv 128
                 ++ e+++ ++++++++ +           +++l iDE++ l   e+++++ + l+    + +++++
  EEA22909.1 262 DTGEIRSEVRDQINTKVAewkeegkaeiiPGVLFIDEVHML-DIECYSYINRALE--AELAPIVIM 324
                 556667777777777777777777789999***********.8888888866666..555555555 PP

>> AAA_25  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.1    0.0001      0.12      32      63 ..      68      99 ..      55     110 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.0001
      AAA_25 32 agelallaGapgtGKttlaldlalavatGkpw 63
                ag  +l+aG+p tGKt++a+ +a ++  + p+
  EEA22909.1 68 AGRAVLIAGPPSTGKTAIAMGMAQSLGPDVPF 99
                7999******************9887666665 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   0.0    0.0018         2       2      32 ..      72     103 ..      71     141 .. 0.80
   2 ?    1.6   0.0      0.22   2.5e+02      65      90 ..     290     315 ..     260     322 .. 0.72

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.0018
                 EEEE--SSSSHHHHHHHGGGGB.S--EEEEE- CS
       AAA_5   2 vlLvGppGtgKselaerlaaal.nreveyvql 32 
                 vl+ Gpp tgK+ +a+ +a+ l  +  ++ + 
  EEA22909.1  72 VLIAGPPSTGKTAIAMGMAQSLgPDVPFTTLA 103
                 899*****************998555555544 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.22
                 G-SEEEEESGGG--HHHHHHHHHHHH CS
       AAA_5  65 egeilvlDEveraesevlnsLlslle 90 
                  + +l++DEv++++ e  +  ++ le
  EEA22909.1 290 IPGVLFIDEVHMLDIECYSYINRALE 315
                 6789*******999888777777776 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   0.00012      0.14       2      43 ..      72     118 ..      72     183 .. 0.84

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.00012
      AAA_33   2 vllvGlpGsGKstlaerllkklg....avllssdtlrr.rlfgtdqq 43 
                 vl+ G+p +GK+  a ++++ lg    +++l+s ++++  + +t+  
  EEA22909.1  72 VLIAGPPSTGKTAIAMGMAQSLGpdvpFTTLASSEVFSlDMSKTEAL 118
                 6889*******************999988888887666577765544 PP

>> AAA_7  P-loop containing dynein motor region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.5   0.0   0.00057      0.64      33      60 ..      69      96 ..      51     121 .. 0.86
   2 ?   -0.1   0.1      0.52   5.9e+02     103     117 ..     293     307 ..     289     311 .. 0.90

  Alignments for each domain:
  == domain 1  score: 9.5 bits;  conditional E-value: 0.00057
       AAA_7 33 kkpvllvGptGtGKtviikdllkkldke 60
                ++ vl+ Gp  tGKt+i++ + ++l ++
  EEA22909.1 69 GRAVLIAGPPSTGKTAIAMGMAQSLGPD 96
                689****************999998754 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.52
       AAA_7 103 vvFvDDlnmpakeky 117
                 v+F+D+++m   e y
  EEA22909.1 293 VLFIDEVHMLDIECY 307
                 79*******999988 PP

>> AAA_11  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.2   0.00018       0.2      18      42 ..      66      94 ..      50     248 .. 0.88

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00018
      AAA_11 18 e....itliqGPPGtgKTktivellsqll 42
                +     +li GPP tgKT   +++ ++l 
  EEA22909.1 66 DiagrAVLIAGPPSTGKTAIAMGMAQSLG 94
                3444468*****************99984 PP

>> TFIID-31kDa  Transcription initiation factor IID, 31kD subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00019      0.21      37      66 ..     398     427 ..     363     454 .. 0.86

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00019
  TFIID-31kDa  37 rytssvLedAkvlaehakkkevslddvrlA 66 
                  ry s++++ +++l+e++k+kev++dd++ +
   EEA22909.1 398 RYASNIITTSQLLSEKRKAKEVNVDDIQRS 427
                  9**************************966 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (468 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       559  (0.0311785); expected 358.6 (0.02)
Passed bias filter:                      445  (0.0248201); expected 358.6 (0.02)
Passed Vit filter:                        62  (0.00345808); expected 17.9 (0.001)
Passed Fwd filter:                        16  (0.000892409); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              16  [number of targets reported over threshold]
# CPU time: 0.60u 0.25s 00:00:00.85 Elapsed: 00:00:00.42
# Mc/sec: 3331.90
//
Query:       EEA22910.1  [L=464]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    7.3e-14   51.2   2.4    2.1e-13   49.7   2.4    1.8  1  GYF       GYF domain


Domain annotation for each model (and alignments):
>> GYF  GYF domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   49.7   2.4   1.2e-17   2.1e-13       1      40 [.     410     453 ..     410     460 .. 0.89

  Alignments for each domain:
  == domain 1  score: 49.7 bits;  conditional E-value: 1.2e-17
         GYF   1 WeYk....dpqgevqGPFsseeMqkWykagYFkdgllvrrveds 40 
                 WeY+     + ge++GP+++++Mq+W++agYF +g+++rrv+ +
  EEA22910.1 410 WEYRwsdaRDGGETHGPYDGAMMQSWNDAGYFGEGVEFRRVGGT 453
                 ******8747******************************9653 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (464 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1154  (0.064365); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3184.87
//
Query:       EEA22911.1  [L=380]
Description: ubiquitin fusion degradation protein Ufd1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      9e-76  253.2   0.0    1.1e-75  252.9   0.0    1.1  1  UFD1      Ubiquitin fusion degradation protein UFD1


Domain annotation for each model (and alignments):
>> UFD1  Ubiquitin fusion degradation protein UFD1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  252.9   0.0   6.2e-80   1.1e-75       1     173 []      29     206 ..      29     206 .. 0.98

  Alignments for each domain:
  == domain 1  score: 252.9 bits;  conditional E-value: 6.2e-80
        UFD1   1 feekyrcysvsm..kaereelekggkiiLPpsaLdeLtrlnieyPmlFelsnkkkkksthagVleFtaeegtvylPewmmenlgleegdlveiesvslp 97 
                 f+e+yrcy+v+m  + ere++++ggk+i+PpsaLd+Ltrl+i+yPmlFel+n +k++ thagVleF+aeeg++ylP w+m++l le gdl++++s++lp
  EEA22911.1  29 FDEYYRCYPVAMlpGPERENVNHGGKVIMPPSALDKLTRLHITYPMLFELHNGAKERMTHAGVLEFIAEEGKIYLPFWLMQTLLLEPGDLIQVKSTDLP 127
                 899**********999*********************************************************************************** PP

        UFD1  98 kgkfvklqpqsedfldisdpkavLekaLrnfatLtkgdvieikyndkvyelkvlevkpes...avsiietdlevdfaeP 173
                  g+f+klqpqs++fldisdpkavLe+a+rnf++Ltkgd +++ ynd+vye++vl+vkp+    a+s++etdlevdfa+P
  EEA22911.1 128 PGRFIKLQPQSTSFLDISDPKAVLENAFRNFSCLTKGDAFTFAYNDQVYEIAVLDVKPDGdkkAISVLETDLEVDFAPP 206
                 *********************************************************987778**************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (380 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       293  (0.0163422); expected 358.6 (0.02)
Passed bias filter:                      228  (0.0127168); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.23s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 2716.77
//
Query:       EEA22912.1  [L=308]
Description: indole-diterpene biosynthesis protein PaxU, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-40  138.6   0.0    1.8e-39  136.1   0.0    1.8  1  DUF829    Eukaryotic protein of unknown function (DUF829)


Domain annotation for each model (and alignments):
>> DUF829  Eukaryotic protein of unknown function (DUF829)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  136.1   0.0   9.8e-44   1.8e-39       2     237 ..      39     303 ..      38     306 .. 0.86

  Alignments for each domain:
  == domain 1  score: 136.1 bits;  conditional E-value: 9.8e-44
      DUF829   2 lvvllGWlgarpkhlaKYsdlYrk..pgativvitspsrdllwrt....krlasaldellellsesqrsey.....wpilfhvfsngGpllylallaal 89 
                 +++l++W++a p+   KY+  Y +  p+a+i+   + + d+ +++     rl++++d l+++  +++ + +      ++ +h fsngG+++++++l+a+
  EEA22912.1  39 TIILAFWMNAPPRAAVKYVVKYAElvPSARIIFLFTNTGDFYISRasyrLRLKPLVDILVASQGDDDAETSkdgndGSVYIHLFSNGGIFATAQILQAY 137
                 89******************************************95666666666666666665555544499*999********************** PP

      DUF829  90 qkaesfkkllpelkglvwDSaPgaghylksakafsavlpksssvki..................vvktrsllalal.altllvelilglesvasrsrka 169
                 ++a+  +k+l+ ++++v+DSaPg+++++  +kafs +lp+     +                  +++++ +++++  + +++  +++   +  +++rka
  EEA22912.1 138 KTAT--GKPLR-VSSMVIDSAPGKPTPSLTIKAFSYALPQTIV--LrqlayallstmiwgtyftRKSLGLMWRVFWkRPDKNDDVVVYGDDPLADTRKA 231
                 ****..****8.*****************************44..255678889999999988655555555555325689999999999999999999 PP

      DUF829 170 lndlatkplrcpq.....lylySkaDeviswrdveshaeeaeqrgvkvtakkfedspHvahmrkhperYvekv 237
                 + d +    r+p      +ylyS+aDe+++ +dve+ha+ a + +++v+ ++f ++pHv+hmr  perY+  +
  EEA22912.1 232 ILDPEFVVARTPTerikmCYLYSDADELVPGKDVEEHAALASK-SREVELEMFIGTPHVGHMRVSPERYWGII 303
                 888887777766566666***********************98.999***********************876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (308 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       315  (0.0175693); expected 358.6 (0.02)
Passed bias filter:                      298  (0.0166211); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.28s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2199.05
//
Query:       EEA22913.1  [L=627]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.1e-135  453.3   0.2   1.4e-135  453.0   0.2    1.1  1  DUF4246   Protein of unknown function (DUF4246)


Domain annotation for each model (and alignments):
>> DUF4246  Protein of unknown function (DUF4246)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  453.0   0.2  7.6e-140  1.4e-135       1     451 [.      66     561 ..      66     563 .. 0.88

  Alignments for each domain:
  == domain 1  score: 453.0 bits;  conditional E-value: 7.6e-140
     DUF4246   1 ltvrEvamlklmeaitdkpdWekkvfdeeivakWkkealaaeeeellsekmadwcieELrdkakefeetglvavldsssavvks..DtlvseelkeeLk 97 
                 +t+rE +ml+l++++tdk+dW +kvfd  +++ W ke  +++ e  ++e+m+dw+++EL++kak  ++ g+++v++  ++vvks  D + +e++++eL 
  EEA22913.1  66 VTIREKKMLQLINEFTDKQDWFEKVFDACYIQVWTKELREDP-E--VTENMIDWLTAELKYKAKIARKIGFINVFN--ADVVKScaDFFQHEKFRTELC 159
                 589**********************************65555.4..9*****************************..99999888************* PP

     DUF4246  98 kavakLedvpeeekdwhpgsdeqvldlVhpslfplvYgrtrvlkdgvvkledalesagkGevlek.......................kllskkfqwLP 173
                 +a++kLe+   ++++++  ++e+ +d Vhps+fp+ +g+trvl+d+ ++l+da++s+g+Ge++++                       + +s++fqwLP
  EEA22913.1 160 NAIKKLEQGLGTAPEYQMATEEREMDYVHPSFFPVAFGKTRVLPDRLIGLDDAVASMGQGEIIPVpqdpgpsrhelswniasrsdimpRPYSSRFQWLP 258
                 *************************************************************8866667777788888888888888888********** PP

     DUF4246 174 cevefsedgksvkitSYINnLhpkkhkelYsviekliekaiplwnevlaklkeeereprri..............eeeepeeeeeeeeedeeeeeeree 258
                 ++v f+ dg+   ++SYINn+hp++ k+lY+v+ekl++k+ip+w+ +l+++k+  + + r+              +  ep+  e+ + e++  +eer +
  EEA22913.1 259 SDVYFRPDGS-SYFASYINNIHPSRDKTLYTVLEKLLDKIIPMWDLTLTPIKSPIHPRARVelqevryvekepgkT--EPKPVETPQ-EERGDYEERLR 353
                 *******998.9**************************************95555555555555556666555322..232222222.2335599999* PP

     DUF4246 259 eweeerrkvvlpepeksfsy...................keeksvklkeeefkkkgLqVivklanieLtPekpeyeggswhveGqlnEhIvAtalyyyd 338
                  w++++ k+v+pep+ +f++                   +  + ++l ++e+ ++gLqViv++a++  tP++p +e   wh+eGq+nEh++A+++y+++
  EEA22913.1 354 FWRRKWFKAVQPEPG-EFAPvgippeimndlppteqnkhRLLDLMNL-KKEYGHRGLQVIVRIADMAPTPDQPIFE-VPWHMEGQINEHLCASSIYFFE 449
                 *************84.4555678888888888866533233334444.8***************************.89******************** PP

     DUF4246 339 seNitesrLsFrqkvdeeeakeeleyeqddhealeevfgiene.sslqelGsvetkegrllaFpNvlqhrvepfeLaDktkpGhrkilaLfLVDPhiri 436
                 ++Ni++ r++Frq +d+ +a ++l+ye+ d+ +le++fg++++ s++qe+G +e+++gr++++pN+lqh+v  f+L+Dkt+ Gh++ + ++LVDP+iri
  EEA22913.1 450 MKNIESVRMHFRQISDT-QAFSDLNYERGDTIWLEDIFGMKHDeSPVQEVGYIECPQGRMITWPNTLQHNVV-FTLKDKTQVGHVHAINFMLVDPNIRI 546
                 *************7777.6789********************6377************************96.************************** PP

     DUF4246 437 istanVppQqkdwwa 451
                 istanVppQ+ dw  
  EEA22913.1 547 ISTANVPPQRLDWKP 561
                 *************75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (627 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       561  (0.0312901); expected 358.6 (0.02)
Passed bias filter:                      481  (0.026828); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.61u 0.26s 00:00:00.87 Elapsed: 00:00:00.43
# Mc/sec: 4382.21
//
Query:       EEA22914.1  [L=1212]
Description: DNA-directed RNA polymerase III, beta subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   8.7e-124  413.5   0.4   1.3e-123  413.0   0.0    1.5  2  RNA_pol_Rpb2_6  RNA polymerase Rpb2, domain 6
    1.2e-55  188.2   0.7    1.8e-55  187.6   0.7    1.3  1  RNA_pol_Rpb2_1  RNA polymerase beta subunit
      7e-32  109.7   0.4    1.6e-31  108.5   0.4    1.7  1  RNA_pol_Rpb2_7  RNA polymerase Rpb2, domain 7
    2.4e-26   92.6   3.3    5.9e-26   91.3   3.3    1.7  1  RNA_pol_Rpb2_2  RNA polymerase Rpb2, domain 2
    5.7e-25   87.4   0.6    1.3e-24   86.2   0.6    1.7  1  RNA_pol_Rpb2_4  RNA polymerase Rpb2, domain 4
    2.3e-19   69.3   0.0    5.6e-19   68.1   0.0    1.7  1  RNA_pol_Rpb2_3  RNA polymerase Rpb2, domain 3
    9.4e-10   38.9   2.5    4.5e-09   36.7   2.5    2.3  1  RNA_pol_Rpb2_5  RNA polymerase Rpb2, domain 5
  ------ inclusion threshold ------
          6    6.5   6.7       0.53    9.8   2.0    1.8  2  zn-ribbon_14    Zinc-ribbon


Domain annotation for each model (and alignments):
>> RNA_pol_Rpb2_6  RNA polymerase Rpb2, domain 6
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.1   0.3       2.7   6.1e+03     152     200 ..     247     287 ..     243     302 .. 0.61
   2 !  413.0   0.0  5.7e-127  1.3e-123       1     390 []     742    1115 ..     742    1115 .. 0.95

  Alignments for each domain:
  == domain 1  score: -4.1 bits;  conditional E-value: 2.7
                     --SS-EEETT-EEE---..B-----...-----------..-B---EE- CS
  RNA_pol_Rpb2_6 152 vrvgaevkegdilvgkvtkgeteltpeekllraifgekarevkdtslrv 200
                     + v+++++++ i+v           p++++++a  +++++e k +s+ +
      EEA22914.1 247 ILVQEQLSKNRIIVET--------DPKKEIVQASVTSSSNERKSKSYII 287
                     5566666666666655........4555666666666666666666554 PP

  == domain 2  score: 413.0 bits;  conditional E-value: 5.7e-127
                      HHHT-SS-TTB-HHHHHHHHHHGGGB-S---TTTTT---SSEEEESS----SSB-S.TTTTTS........GGGS-SEEEEEBBBS--TTTTT CS
  RNA_pol_Rpb2_6    1 vaklapvvehvqspriiiqaamekqalgiyslnkfkrsnqktyllcinqkPlvktgdkveagqvldgpatekgelalGqnavVAvmsyeGYni 93  
                      va l+p+++h+qspr+++q+am+kqa+g ++ n+f r+++ +yl++++qkP+vkt+ ++e+++        +++l++Gqna+VAvmsy+GY+i
      EEA22914.1  742 VAGLIPYPHHNQSPRNTYQCAMGKQAIGAIASNQFLRIDSLLYLMVYPQKPMVKTR-TIELIK--------YDQLPAGQNATVAVMSYSGYDI 825 
                      6899****************************************************.******........********************** PP

                      TT-EEEBCHHHHTTTT-EEEEEE..EEE--SSSS---.-S--..-....-SS-GGGS-TTSB--SS-EEETT-EEE---..B-----...--- CS
  RNA_pol_Rpb2_6   94 EDaiilnerlvdrdvftsihikeyeveardtklgeeeitrdipnv....seealkkLdedGivrvgaevkegdilvgkvtkgeteltpeekll 182 
                      EDa++ln+ +vdr++ ++ ++++y  + +++++g+e+  r ++ +      ++++ Ld+dG+  vga v++g+++++k         + +  +
      EEA22914.1  826 EDALVLNKGSVDRGFGRCQVFRKYVANLKSYPNGSEDRLRGPELDeegaPITKHALLDTDGLAAVGAVVSQGQVYINKE----VPAAAFSAGI 914 
                      ***********************99999*******999999877766767788999**********************4....3344445666 PP

                      --------..-B---EE--TT-EEEEEEEEE.......EE-TT--EEEEEEEEEEE---TT-BEEETTS---BBEEEB-TTTSEEETTS---S CS
  RNA_pol_Rpb2_6  183 raifgekarevkdtslrvksgeegvVdkvkvfsrekgdelkagvnklvkvyvaqkRklqvGDKfasrhGqKGvvslilpqeDmPfledGivvD 275 
                      +     +  +++ + +++k   + ++dkv+v       + ++g +k++kv ++q+R+++vGDKf+srhGqKGvv++i++q DmPf ++Giv+D
      EEA22914.1  915 TGSDVGRPPDYNPAPMTYKLPDPSYIDKVMV-------SVTEGESKIYKVQTRQTRRPEVGDKFSSRHGQKGVVGIIAEQADMPFNDQGIVPD 1000
                      7777777778999******************.......89999************************************************** PP

                      EEE-GGGCHHH-BTTHHHHHHHHHCCCSSSS--B--TT-...-HHHHHHHHHTTS-TT-EE-EEETTTS-B-SS-EEB-EEEEEEBS--CCCS CS
  RNA_pol_Rpb2_6  276 ivlNPlgvPSRmtigqllEtllgkaaalegkkvdatvFdgakeeeikelLeeagleasGkevlydGrtGekleaeifvGviYylkLkhlvedK 368 
                      i++NP+g+PSRmt+g+llE+++gka+ l+g++ ++t+F g+  e+++  L  +g+++ Gk++l++G+tGe+l  ++f+G+iYy+kLkh+v+dK
      EEA22914.1 1001 IIMNPHGFPSRMTVGKLLELVAGKAGVLSGQHGYGTAFGGSPVEQMSAILVDKGFSYGGKDYLTSGITGEPLPFYVFMGPIYYQKLKHMVQDK 1093
                      ***************************************9999************************************************** PP

                      ----SS--B-TTT--B-SCGGG CS
  RNA_pol_Rpb2_6  369 ihaRstGpyslltqQPlgGkaq 390 
                      +h+RstGp  +lt+QP++G+++
      EEA22914.1 1094 MHSRSTGPRATLTRQPTEGRSR 1115
                      ********************86 PP

>> RNA_pol_Rpb2_1  RNA polymerase beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  187.6   0.7   7.9e-59   1.8e-55       1     202 [.     103     486 ..     103     487 .. 0.97

  Alignments for each domain:
  == domain 1  score: 187.6 bits;  conditional E-value: 7.9e-59
                     CTTHHHHHHHHHHHHTHHHHHCTTSSECCHCSSSHCSSSCEEEEEEEEEEESCSSEC..TT..SCEEES.HHHHHHCTSBXEEEEEEEEEEEECC CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  RNA_pol_Rpb2_1   1 gLvsqqldSFnkfveqdlekiikeeaaieseeeiqssgeelelkfvsirlgkPvvde..sd..asereiyPkearlrnltYsaplyvklklvvye 91 
                     gLv+q++dS+n+f+e +l+ki++++++i s+ ++      + lkf +i++g P  ++  +d   s+ +++P+e+rlr++tY ap++v+ ++++  
      EEA22914.1 103 GLVKQHIDSYNYFIEVQLKKIVEASSTIYSDADSA-----FFLKFTDIYVGSPRRSDepKDsvESDSTVTPNECRLRDMTYAAPIFVDFTYKR-- 190
                     69******************************976.....*************999878663356789*************************.. PP

                     CCTCCEEEEEEEEEEEEEXBTTSTTSSSTTS.HHHHHHTTS.TTS..SSEEETTCEEEEXEEEE............................... CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............................... RF
  RNA_pol_Rpb2_1  92 kdnkeeikeeevyiGelPlMlrskacvlseaseeelvelkEcpldqGGyFiinGtekvivaqek............................... 155
                        k++ ++++v iG++P+Mlrs++cvls+++++e+  l+Ecpld+GGyFi+nGtekvi++qe+                               
      EEA22914.1 191 --GKDKVTQRRVPIGRMPIMLRSSKCVLSNKKPNEMHLLNECPLDPGGYFIVNGTEKVILVQEQlsknriivetdpkkeivqasvtsssnerksk 283
                     ..8999***************************************************************************************** PP

                     ............................................................................................... CS
                     ............................................................................................... RF
  RNA_pol_Rpb2_1 156 ............................................................................................... 155
                                                                                                                    
      EEA22914.1 284 syiilkkdrlylkhnvlsedvplvivlkamgvhsdkemmllvagvddvyqedfainfeeaikqnvftqqqaldwigskikinrgkiggykkthie 378
                     *********************************************************************************************** PP

                     .........................................................XHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTSS....S CS
                     .........................................................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....x RF
  RNA_pol_Rpb2_1 156 .........................................................laGeLlaslfrvllkklerdvkerlqkslekld....d 189
                                                                              laG+Lla lf++l+kk++ d+k+++ k+l+k +    d
      EEA22914.1 379 eaieaissviishvevtdmdfrpkaiyvanmarrvlmakhdsdmvddrdyvgnkrleLAGQLLALLFEDLFKKFQFDIKMNITKVLGKRRreifD 473
                     ****************************************************************************************9988888 PP

                     SSHHHHSCSHHHH CS
                     xxxxxxxxxxxxx RF
  RNA_pol_Rpb2_1 190 lmlqllvnakpit 202
                     +m+ ++++ ++it
      EEA22914.1 474 AMSVVTLHGNHIT 486
                     9999998888887 PP

>> RNA_pol_Rpb2_7  RNA polymerase Rpb2, domain 7
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  108.5   0.4   7.3e-35   1.6e-31       1      85 [.    1117    1201 ..    1117    1203 .. 0.98

  Alignments for each domain:
  == domain 1  score: 108.5 bits;  conditional E-value: 7.3e-35
                      BBEEEEHHHHHHHHHHTBHHHHHHHHTTTTTEEEEEEESSSSSCCCEEEBTTTTCSSSEEEEEEEHHHHHHHHHHHHTTBEEEEE CS
  RNA_pol_Rpb2_7    1 GGlrfGEMErdaliayGaaalLkerltikSDavevdvcgrckllaaaneCkivkseekiekveipeafklLlqeLqslgialkll 85  
                      GGlr+GEMErd+liayG+++lL erl+ +SD+ evd+c++c+ + ++n+C+ ++s++ + k++ip+a+klL+qeL s++++ +l+
      EEA22914.1 1117 GGLRLGEMERDCLIAYGTSQLLLERLMLSSDKHEVDICEKCGFMGYQNWCQRCRSSRGVVKMTIPYAAKLLIQELLSMNVTARLK 1201
                      9*******************************************************************************99986 PP

>> RNA_pol_Rpb2_2  RNA polymerase Rpb2, domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   91.3   3.3   2.6e-29   5.9e-26       2     190 .]     255     435 ..     254     435 .. 0.91

  Alignments for each domain:
  == domain 1  score: 91.3 bits;  conditional E-value: 2.6e-29
                     TSCEEEEE-SSSSSESSSCCEECCCEEEEECCCCSTSCEEEEECTTSSSEEEHHHHHHHTT--STTHHHHHHTSSSTTHHHHHHHHHHHHHHCTS CS
  RNA_pol_Rpb2_2   2 sngiyvekekdknkisatvtsslisqrgsvlklekdgktliwtriskkrkipivivlkAlglvsdreIlericydsedsqlleelleeleekeei 96 
                     +n+i+ve +++k+ ++a+vtss+ +++++ + + k+++ ++++++   +++p+vivlkA+g+ sd+e +  + + ++ +q  ++++ e+  k+++
      EEA22914.1 255 KNRIIVETDPKKEIVQASVTSSSNERKSKSYIILKKDRLYLKHNV-LSEDVPLVIVLKAMGVHSDKEMMLLVAGVDDVYQEDFAINFEEAIKQNV 348
                     8***************************************99995.555*************************9999***************** PP

                     SSCHHHHHHHHH.....CSSTTSSSCCCCCHHHHHHHCHHHHHHHTTTTSSTTTTTSSSTCHH..HHHHHHHHHHHHHHHHTTSSSS--TTSGGG CS
  RNA_pol_Rpb2_2  97 qtqeealdyigk.....vvalrrgeearlqsareilqkrydlgeigreklnkhlglseslenkrlkaqdilymidrLlslklgrrevDDiDhlgn 186
                      tq++ald ig+     + +++  +++ +++a e++            ++  h+++    ++   ka +++ m++r+l++k+++ +vDD+D++gn
      EEA22914.1 349 FTQQQALDWIGSkikinRGKIGGYKKTHIEEAIEAI----------SSVIISHVEVTDMDFRP--KAIYVANMARRVLMAKHDSDMVDDRDYVGN 431
                     ************554444455555677777777777..........478888*******9999..****************************** PP

                     EEEE CS
  RNA_pol_Rpb2_2 187 kRvr 190
                     kR++
      EEA22914.1 432 KRLE 435
                     **95 PP

>> RNA_pol_Rpb2_4  RNA polymerase Rpb2, domain 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.2   0.6     6e-28   1.3e-24       3      62 .]     615     674 ..     613     674 .. 0.98

  Alignments for each domain:
  == domain 1  score: 86.2 bits;  conditional E-value: 6e-28
                     CTT-BEEE-S-HCCHHHHHHHHCCTTSS-TT-EEEE-TTT--EEEE-SSEEB-EEEEE-S CS
  RNA_pol_Rpb2_4   3 vNGrllGvtrdpkklvetlRelRRkgkiseevsivlnekqkevkiatDgGRvcRPliiVe 62 
                     +NG+ +++tr+pk++++++R+lRR g+ise+vsi++n++q+ v+iatD GR+cRPli+Ve
      EEA22914.1 615 MNGTPIALTRRPKYFLNAFRRLRRMGRISEFVSIYINHHQRAVHIATDDGRICRPLIVVE 674
                     7**********************************************************7 PP

>> RNA_pol_Rpb2_3  RNA polymerase Rpb2, domain 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   68.1   0.0   2.5e-22   5.6e-19       2      68 .]     513     576 ..     512     576 .. 0.97

  Alignments for each domain:
  == domain 1  score: 68.1 bits;  conditional E-value: 2.5e-22
  RNA_pol_Rpb2_3   2 vldrlnplselshlrrvsslrgglskerkttevRdlhpshwGriCpveTPEGencGlvksLallarv 68 
                     vl rl++++ l  ++r+ss    ++k+rk + +R l+ps++G++Cp++TPEGe cGlvk+Lal++++
      EEA22914.1 513 VLSRLSYIAALGMMTRISSQ---FEKTRKVSGPRALQPSQFGMLCPSDTPEGEACGLVKNLALMTHI 576
                     789***************88...*****************************************987 PP

>> RNA_pol_Rpb2_5  RNA polymerase Rpb2, domain 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   36.7   2.5     2e-12   4.5e-09       1      58 []     695     735 ..     695     735 .. 0.91

  Alignments for each domain:
  == domain 1  score: 36.7 bits;  conditional E-value: 2e-12
                     HHHHHHTTSEEEEEHHHHTT--EESSTTTCSST-SSTTTSS--TTSSSST-SEEES-G CS
  RNA_pol_Rpb2_5   1 wddLlregvvEylDaeEEetamIamtpedleksreekealeekenskshtyTHcEIhP 58 
                     +dd+l++g+vEylD++EE++++Ia++++d+ +                  +TH+EI+P
      EEA22914.1 695 FDDFLAQGLVEYLDVNEENDSNIAIYEKDVIDI-----------------TTHLEIEP 735
                     9****************************9554.................68888888 PP

>> zn-ribbon_14  Zinc-ribbon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.2       4.5     1e+04      17      24 ..     563     570 ..     563     571 .. 0.86
   2 ?    9.8   2.0   0.00024      0.53       3      18 ..    1154    1169 ..    1152    1170 .. 0.94

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 4.5
  zn-ribbon_14  17 ACvLLegL 24 
                   AC L ++L
    EEA22914.1 563 ACGLVKNL 570
                   99999998 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.00024
  zn-ribbon_14    3 CerCGylSSqkiCkAC 18  
                    Ce+CG++  q  C+ C
    EEA22914.1 1154 CEKCGFMGYQNWCQRC 1169
                    **************88 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1212 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       740  (0.0412739); expected 358.6 (0.02)
Passed bias filter:                      584  (0.0325729); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.87u 0.33s 00:00:01.20 Elapsed: 00:00:00.48
# Mc/sec: 7654.44
//
Query:       EEA22915.1  [L=1026]
Description: RNA-binding protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
      7e-57  186.0   3.0    5.8e-08   32.0   0.0    8.4  8  PUF         Pumilio-family RNA binding repeat
  ------ inclusion threshold ------
       0.14   11.5   0.0       0.28   10.5   0.0    1.4  1  DUF4901     Domain of unknown function (DUF4901)


Domain annotation for each model (and alignments):
>> PUF  Pumilio-family RNA binding repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   0.0   8.2e-08   0.00074       3      27 ..     611     635 ..     609     643 .. 0.82
   2 !   30.2   0.0   2.4e-11   2.2e-07       5      34 ..     649     678 ..     646     679 .. 0.87
   3 !   23.0   0.0   4.6e-09   4.1e-05       4      34 ..     684     715 ..     683     716 .. 0.89
   4 !   32.0   0.0   6.4e-12   5.8e-08       2      34 ..     719     751 ..     718     752 .. 0.95
   5 !   23.6   0.0     3e-09   2.7e-05      10      31 ..     763     784 ..     757     788 .. 0.84
   6 !   23.6   0.0     3e-09   2.7e-05       2      28 ..     791     817 ..     790     824 .. 0.82
   7 !   15.9   0.0   8.2e-07    0.0074       2      26 ..     827     851 ..     826     856 .. 0.90
   8 !    9.8   0.0   7.2e-05      0.65      10      35 .]     873     898 ..     868     898 .. 0.86

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 8.2e-08
                 GGGHHHHHTSTTHHHHHHHHHHHSC CS
         PUF   3 kgnlvqLstdqyGnyvvQkllehat 27 
                 +g+l  L++dq+G++ +Q+ le   
  EEA22915.1 611 RGELYGLCKDQHGCRYLQRKLEERN 635
                 688999***************9754 PP

  == domain 2  score: 30.2 bits;  conditional E-value: 2.4e-11
                 GHHHHHTSTTHHHHHHHHHHHSCHHHHHHH CS
         PUF   5 nlvqLstdqyGnyvvQkllehateeqkkli 34 
                 ++v+L+td++Gny++Qklle++   q+ ++
  EEA22915.1 649 HVVELMTDPFGNYLCQKLLEYSNDDQRTRL 678
                 89******************9777776655 PP

  == domain 3  score: 23.0 bits;  conditional E-value: 4.6e-09
                 GGHHHHHTSTTHHHHHHHHHHH.SCHHHHHHH CS
         PUF   4 gnlvqLstdqyGnyvvQklleh.ateeqkkli 34 
                 + lv ++ +q+G++++Qk++e  +t+ q++ +
  EEA22915.1 684 PQLVPIALNQHGTRALQKMIEFvSTPQQIRMV 715
                 56899*****************9999999876 PP

  == domain 4  score: 32.0 bits;  conditional E-value: 6.4e-12
                 HGGGHHHHHTSTTHHHHHHHHHHHSCHHHHHHH CS
         PUF   2 ikgnlvqLstdqyGnyvvQkllehateeqkkli 34 
                 ++g++v+L++d +Gn+v+Qk+l +++ e+ ++i
  EEA22915.1 719 LRGHVVDLVQDLNGNHVIQKCLNRLSAEDAQFI 751
                 689***************************998 PP

  == domain 5  score: 23.6 bits;  conditional E-value: 3e-09
                 HTSTTHHHHHHHHHHHSCHHHH CS
         PUF  10 stdqyGnyvvQkllehateeqk 31 
                  t+++G++v+Q++++ha+ eq+
  EEA22915.1 763 GTHRHGCCVLQRCIDHASGEQR 784
                 58**************999987 PP

  == domain 6  score: 23.6 bits;  conditional E-value: 3e-09
                 HGGGHHHHHTSTTHHHHHHHHHHHSCH CS
         PUF   2 ikgnlvqLstdqyGnyvvQkllehate 28 
                 i  n  +L++d++GnyvvQ++l+ +++
  EEA22915.1 791 ITSNAFSLVQDPFGNYVVQYILDLSEP 817
                 567889*****************5544 PP

  == domain 7  score: 15.9 bits;  conditional E-value: 8.2e-07
                 HGGGHHHHHTSTTHHHHHHHHHHHS CS
         PUF   2 ikgnlvqLstdqyGnyvvQklleha 26 
                 ++gn+  Ls+ ++ ++v++k+l +a
  EEA22915.1 827 FLGNIPALSKQKFSSNVIEKCLRTA 851
                 789999****************975 PP

  == domain 8  score: 9.8 bits;  conditional E-value: 7.2e-05
                 HTSTTHHHHHHHHHHHSCHHHHHHHH CS
         PUF  10 stdqyGnyvvQkllehateeqkklil 35 
                   d y+nyvvQ+  + a+  ++ +i+
  EEA22915.1 873 LRDSYANYVVQTAMDFADADNRNRII 898
                 569**********9999999888875 PP

>> DUF4901  Domain of unknown function (DUF4901)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   3.1e-05      0.28      79     118 ..      88     127 ..      78     130 .. 0.92

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 3.1e-05
     DUF4901  79 qakeiadaflkkhlkelseaytyirveadrryveieyrqe 118
                  a +i ++ l  h++e  +++  ir++++++ ++iey++e
  EEA22915.1  88 SATHIHKSQLVSHQPEYVAFFILIRMQIEKKRQHIEYMRE 127
                 588999********************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1026 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       773  (0.0431145); expected 358.6 (0.02)
Passed bias filter:                      560  (0.0312343); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.79u 0.32s 00:00:01.11 Elapsed: 00:00:00.49
# Mc/sec: 6297.04
//
Query:       EEA22916.1  [L=561]
Description: origin recognition complex subunit Orc5, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-83  280.3   0.0    2.5e-83  279.9   0.0    1.2  1  ORC5_C    Origin recognition complex (ORC) subunit 5 C-termin
    2.2e-18   67.2   0.1    3.8e-18   66.4   0.1    1.4  1  AAA_16    AAA ATPase domain


Domain annotation for each model (and alignments):
>> ORC5_C  Origin recognition complex (ORC) subunit 5 C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  279.9   0.0   2.8e-87   2.5e-83       1     285 []     192     556 ..     192     556 .. 0.91

  Alignments for each domain:
  == domain 1  score: 279.9 bits;  conditional E-value: 2.8e-87
      ORC5_C   1 ihFppytreevleils...kekps.........ngeeeeeeataklyerFvslvydslvkptardipelrsiceklWprFvaPildgelkpe..dfsrl 85 
                 i+Fppytr+e+++i++       +         n++  + ++ + +y++Fv++vydslv+pta +ip++rsiceklWprF +P+++ge++ e  df+rl
  EEA22916.1 192 INFPPYTRKEAITIVTaagL---PkvdvlpddyNSKISSTTSMEGIYAQFVATVYDSLVGPTAGTIPSFRSICEKLWPRFLQPMQNGEVSGEgwDFTRL 287
                 89**************6661...344567777788888888999*********************************************76699***** PP

      ORC5_C  86 laanralfrdqgesalaeelv......ektaasssassasskssssklpeLpylaklLLiAAYLASynpprlDlrlFsktsgks.kkr......rkrrk 171
                 l +nra+f+ qges+l++++v      +k++ ++++++++s +s++klp+Lpy+++l+L++AY+AS++p+rlD+++Fsk+s++s ++r      r+r k
  EEA22916.1 288 LLRNRAMFKIQGESMLVHHIVsapegtNKEDPKTKKRKLNSLTSTPKLPSLPYFPTLVLTSAYVASHTPQRLDTIFFSKFSSSSlSARnkrshhRRRLK 386
                 *************************996677777777778899999**************************************999966566556777 PP

      ORC5_C 172 gssqkskeka...kskkrk..................................................isqkllgPkaFpLeRllAIfqailpeeeae 217
                   sq+++++         +                                                   s++ll++++F+LeRl+AI++ai+p+++a+
  EEA22916.1 387 LLSQAQADDDndnG----NtpkkgkrvktkitksmldsafattsattsaitgdnaasggaggggttqltGSSTLLTARPFTLERLVAIYHAIDPNPPAN 481
                 77777776665441....14466788899999******************************************************************9 PP

      ORC5_C 218 pseeessetlsvdvlsqiatLvslrllvrtsaaa..........gdkldgsekwrvnVswevirelArsvgfeleeYL 285
                 +  + +   +++++++++atL++lrl+v++++++          + ++d +ekw +nVs +++ elA+++g+e++e+L
  EEA22916.1 482 ALYTLP---TADAIYNELATLRRLRLVVPATGGSsqnvgggataMMTADVGEKWSINVSGDWVGELAKGIGVEVGEWL 556
                 988888...**********************988**********9********************************9 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.4   0.1   4.2e-22   3.8e-18       1     170 []      16     172 ..      16     174 .. 0.88

  Alignments for each domain:
  == domain 1  score: 66.4 bits;  conditional E-value: 4.2e-22
      AAA_16   1 rlvGReeeleqLlsalervrsgrpelvllsGesGvGKsslvrellralekdggiflrgkcdqlesaipysalaqalareellrqllde..aesaeleaw 97 
                 ++++R+ +++qL+++l+    ++p+ ++l+G s++ Ks+lv ++l++l +++   +  +c+++            ++ ++ll+++l e  ++   +++w
  EEA22916.1  16 QWPCRKTQIRQLAALLD-PQIPSPSTIVLYGISATCKSTLVSAVLDSLPARH---AIIRCVEC------------ITSRHLLQKILLEtlHSFGMQDHW 98 
                 79**************9.5568899************************997...77888888............888899999999988888888999 PP

      AAA_16  98 rekleealaavpelagaeasrllellkrllallsrder........plvlvlDdlqwadeaslqllaaLlrlles.kpllvv 170
                  ++ +++ +        + s ll +l +++a +++ ++        ++vlvlD +++ ++as++llaaL+rl+e+ ++l+vv
  EEA22916.1  99 EKFGKGRCE--------HVSTLLIHLGDIFAAARNSKKsdgevggeKFVLVLDGIDRQRDASQMLLAALARLGEMiPSLTVV 172
                 998877666........889999999999988888666999999989**************************995477665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (561 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       486  (0.0271069); expected 358.6 (0.02)
Passed bias filter:                      376  (0.0209716); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.24s 00:00:00.82 Elapsed: 00:00:00.43
# Mc/sec: 3904.49
//
Query:       EEA22917.1  [L=222]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    6.4e-14   52.1   1.0    6.4e-14   52.1   1.0    1.7  2  GFA       Glutathione-dependent formaldehyde-activating enzym


Domain annotation for each model (and alignments):
>> GFA  Glutathione-dependent formaldehyde-activating enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.1      0.21   3.8e+03      41      60 ..      72      90 ..      52      97 .. 0.61
   2 !   52.1   1.0   3.5e-18   6.4e-14       1      79 [.     101     187 ..     101     200 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 0.21
         GFA 41 adsgnkvtrsfCpeCgsply 60
                ++ +n+  +  C +Cg+  +
  EEA22917.1 72 SNVSNENAKISC-QCGTVTF 90
                344444444555.4776666 PP

  == domain 2  score: 52.1 bits;  conditional E-value: 3.5e-18
         GFA   1 alChCsdCrkasgsaftanavvkaealelleg....elkeykktadsgnkvtrsfCpeCgsplyse....esaapevvivrvGtldd 79 
                 ++ChC++C+k+s+saf   a+++ae +  l +    ++ ++++tadsgn+++ +fC+ Cg+++ ++       a+ ++ v+ G+++ 
  EEA22917.1 101 YICHCTECQKQSASAFGITAMFPAEGMWPLPEdiqpHVGKWTRTADSGNTLECYFCKCCGVRVLHRpilpDGTAKPMLSVKGGCVEG 187
                 68***********************99866555777999*************************98766544555588888888875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (222 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       757  (0.0422221); expected 358.6 (0.02)
Passed bias filter:                      325  (0.0181271); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.28s 00:00:00.77 Elapsed: 00:00:00.47
# Mc/sec: 1433.72
//
Query:       EEA22918.1  [L=474]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (474 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       487  (0.0271627); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.52u 0.23s 00:00:00.75 Elapsed: 00:00:00.40
# Mc/sec: 3530.38
//
Query:       EEA22919.1  [L=927]
Description: P-type ATPase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.1e-43  146.7   4.6    5.1e-43  146.7   4.6    2.4  2  E1-E2_ATPase     E1-E2 ATPase
      2e-15   57.7   0.1    5.8e-15   56.2   0.1    2.0  1  Hydrolase        haloacid dehalogenase-like hydrolase
    2.1e-11   43.3   0.0    4.3e-11   42.3   0.0    1.5  1  Cation_ATPase_N  Cation transporter/ATPase, N-terminus
    0.00034   20.7   0.0    0.00076   19.5   0.0    1.5  1  Cation_ATPase    Cation transport ATPase (P-type)
  ------ inclusion threshold ------
      0.013   15.3   0.1      0.022   14.5   0.1    1.3  1  Hydrolase_3      haloacid dehalogenase-like hydrolase
      0.025   14.4   0.0      0.059   13.1   0.0    1.6  1  AIM24            Mitochondrial biogenesis AIM24
       0.77   10.0   6.3       0.22   11.8   0.2    2.9  3  DUF423           Protein of unknown function (DUF423)


Domain annotation for each model (and alignments):
>> E1-E2_ATPase  E1-E2 ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  146.7   4.6     2e-46   5.1e-43       4     181 .]     184     363 ..     181     363 .. 0.98
   2 ?   -0.5   0.1       0.3   7.8e+02      51      79 ..     560     588 ..     550     592 .. 0.83

  Alignments for each domain:
  == domain 1  score: 146.7 bits;  conditional E-value: 2e-46
                   --EEEEE-TTS-EEEEGGG--TTSEEEEETT-B--SEEEEEEE-S..EEE-TTTS---S-EE-G-TTEE-TT-EEEE-EEEEEEEE-TTTSTTTTTS CS
  E1-E2_ATPase   4 pptakvirdgteeeidakelvpGDivllkagdrvpaDgrivegsa..evdesaLTGEslpvekekgdmvfsGtvvvsgeakavVtatgedtelgkia 98 
                   + +a v+r+ +++e++a+e+vpGDi+ +++g ++paDg+i+ + a  ++d+sa+TGEs +v+k  gd++++++ v++ge    Vtatg +t++g++a
    EEA22919.1 184 ALKAAVFRNSRVVEVAASEVVPGDIIHIEEGTIIPADGKIMTEGAfiQIDQSAITGESFAVDKYFGDTCYASSAVKRGETFLLVTATGDSTFVGRAA 280
                   56899******************************************************************************************** PP

                   TTS--------HHHHHHHHHHHHHHHHHHHHHHHHHHS-STTTSSTTHHHHHHHHHHHHHS-TTHHHHHHHHHHHHHHHHHHT CS
  E1-E2_ATPase  99 rlveeakskktplqkkldklgkvlvpvvlliallvflialllgkslaeallralallvaaiPcaLplavplalalgarrlakk 181
                   +lv++a+s   ++++ l+++g++l + v++ ++ v+++ +++  +++++l ++l++ ++ +P +Lp++v++++a+ga+ lak+
    EEA22919.1 281 ALVNSASSGGGHFTEVLNRIGATLLASVIWTIMSVWVASFFRSVEIIRILEFTLSITIIGVPVGLPAVVTTTMAVGAAYLAKR 363
                   ********************************************************************************996 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.3
                   E-TTTS---S-EE-G-TTEE-TT-EEEE- CS
  E1-E2_ATPase  51 desaLTGEslpvekekgdmvfsGtvvvsg 79 
                      +LTG+++ + +e+  ++  Gt+v + 
    EEA22919.1 560 SVKMLTGDAVGIARETSRQLGLGTNVYNA 588
                   5679********************99875 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.2   0.1   2.2e-18   5.8e-15       3     210 .]     381     653 ..     379     653 .. 0.72

  Alignments for each domain:
  == domain 1  score: 56.2 bits;  conditional E-value: 2.2e-18
                 EEEEESBTTTBCHHHHHHH.....HHHHHCHHHHHHHHHH.................HHCHHHHHHHHHHHHH........HHHHHHHHHETTTE..HH CS
                 xxxxxxxxxxxxxxxxxxx.....xxxxxxxxxxxxxxxx.................xxxxxxxxxxxxxxxx........xxxxxxxxxxxxxx..xx RF
   Hydrolase   3 tvvfDkdGTLttgepsved.....vivsaalalaaaletg.................sehpigkalvaaakar........sgaltgfatfigrg..ay 69 
                  ++ Dk+GTLt+ + s+e+      +++ +l l a l+ g                    p++k    +++ +        s ++t + +++g +  + 
  EEA22919.1 381 ILCSDKTGTLTKNKLSLEEpytvpGVDREDLMLTACLAAGrkkkgldaidkaflkslHHYPYTKSRLSQYHVLefhpfdsvSKKVTAVVRSPGGNkmTC 479
                 6899*******9997777766555666668888888888855554444333333333333333333333333366666666666677777777779999 PP

                 HHTHHHHHHHH.HCHHHHHHHHHHHHHHCHHHHHH...............TTHHHHHHHHHHTHHBHTTHHHHHHHHHHTTEEEEEEESSEHHHHHHHH CS
                 xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxx...............xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase  70 aigkpewltal.dippdlgaaigsaqsqgrtvall...............qaralavftiadplkvkpeaaeavasLkaagievvlltgdnpetaeraa 152
                  +g p ++ +  +  + + +ai++a +    ++                   ++l++   +dp  ++ ++ +++ + k  g+ v +ltgd    a+++ 
  EEA22919.1 480 VKGAPLFVLKTvEEDHPVPEAIDAAYKGKVAEFAArgfrslgiarkyeghPWEILGIMPCSDP--PRYDTFKTISEAKTLGLSVKMLTGDAVGIARETS 576
                 99999999999755555555555555555555555677788877777555449**********..********************************** PP

                 HHTT...............GGGESEEEEHHCES................STTTSHHHHHHHHHHHTSTGGGEEEEESSHHHHHHHHHTT CS
                 xxxx...............xxxxxxxxxxxxxx................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase 153 nqlG...............ddyfdaviasdiet................vakpspegkvaaireLqgkpeevamVGDgvnDaaalaaAg 210
                 +qlG                            +                +a++ pe+k a+++ Lq ++  vam GDgvnDa+ l++A+
  EEA22919.1 577 RQLGlgtnvynaerlglggG------------GdmpgsevydfveaadgFAEVFPEHKYAVVDILQKRGYLVAMTGDGVNDAPSLKKAD 653
                 ****8877766666666662............13333444444445899*****************99999****************98 PP

>> Cation_ATPase_N  Cation transporter/ATPase, N-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.3   0.0   1.7e-14   4.3e-11      10      69 .]      83     142 ..      81     142 .. 0.97

  Alignments for each domain:
  == domain 1  score: 42.3 bits;  conditional E-value: 1.7e-14
  Cation_ATPase_N  10 lekLetdlenGLtqaeaaerlkkyGpNelkekkkkslwvkllkqftnplvilLlvaalvs 69 
                      le+L+t+  +GLt+ e+a r+kkyG N++ +++k+  +vk+l  f  p+  ++++aa+++
       EEA22919.1  83 LEELQTNTHTGLTDTEVASRRKKYGLNQMRKEEKQLPIVKFLMFFVGPIQFVMEAAAVLA 142
                      689******************************************************985 PP

>> Cation_ATPase  Cation transport ATPase (P-type)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0     3e-07   0.00076      22      87 ..     427     490 ..     417     493 .. 0.89

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 3e-07
  Cation_ATPase  22 nktEsALlvlaeklgldteelreetkkvqeipFnssrKrmsvvlklepekkvrlyvKGApeiilkr 87 
                    ++ + A l+  +     t++  ++++ ++  pF+s+ K  + v++  p ++ +  vKGAp  +lk 
     EEA22919.1 427 DAIDKAFLKSLHHY-PYTKSRLSQYHVLEFHPFDSVSKKVTAVVRS-PGGNKMTCVKGAPLFVLKT 490
                    56788899999998.89999999********************998.899999*******999986 PP

>> Hydrolase_3  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.1   8.5e-06     0.022     206     243 ..     636     673 ..     624     685 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 8.5e-06
                  EEEEESSGGGHHHHHHSSEEEEETTS-HHHHHHSSEEE CS
  Hydrolase_3 206 viafGDgeNDieMLeaaglgvAmgnaseevkkaAdyvt 243
                  v+  GDg ND + L++a++g+A++ +s+ + +aAd v 
   EEA22919.1 636 VAMTGDGVNDAPSLKKADTGIAVEGSSDAARSAADIVF 673
                  6678*******************************997 PP

>> AIM24  Mitochondrial biogenesis AIM24
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   2.3e-05     0.059       9      98 ..     197     283 ..     190     302 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2.3e-05
                 -EEEEEE-TT-EEEE-CCGEEEEETTEEEEE--------------EEEEEEES.SS-EEEEE--SSSE..EEEEEEGGTT.EEEEEGGGEEE CS
       AIM24   9 sllsvtLspgeelyaerGalvamsgkvemetgllkalkrlltgeslfllkftakissgtvllapklpg..tivtlelgggdwlivqkdafLA 98 
                 +++  ++ pg+ + +e+G+++  +gk+  e+ + +  + ++tges+ + k+++     t++ ++ ++   t++ ++  +gd+ +v++ a L 
  EEA22919.1 197 EVAASEVVPGDIIHIEEGTIIPADGKIMTEGAFIQIDQSAITGESFAVDKYFGD----TCYASSAVKRgeTFLLVTA-TGDSTFVGRAAALV 283
                 566667889*******************777888887889************53....4555554444669999996.77777777777664 PP

>> DUF423  Protein of unknown function (DUF423)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0       1.7   4.3e+03      45      70 ..     113     138 ..     107     150 .. 0.74
   2 ?   11.8   0.2   8.5e-05      0.22      43      74 ..     752     783 ..     723     796 .. 0.78
   3 ?   -1.5   1.3       1.2     3e+03      38      72 ..     851     884 ..     827     892 .. 0.64

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 1.7
      DUF423  45 aaasrllklagllflaGivlFSgsly 70 
                 + +++l+ + +l+f++G + F  +  
  EEA22919.1 113 KEEKQLPIVKFLMFFVGPIQFVMEAA 138
                 56677888889999999999976655 PP

  == domain 2  score: 11.8 bits;  conditional E-value: 8.5e-05
      DUF423  43 skaaasrllklagllflaGivlFSgslyllal 74 
                 ++ ++ +l++l g+ +++G+vlFSgs  +l++
  EEA22919.1 752 RTPVKWNLPRLWGMSIILGLVLFSGSWITLST 783
                 55667789999****************99976 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 1.2
      DUF423  38 vallaskaaasrllklagllflaGivlFSgslyll 72 
                  +++     +s l  + +++f +G+++  g +++l
  EEA22919.1 851 FGWF-VAGPTSILAVVRVWVFSFGVFCVMGGIFYL 884
                 2222.445666677777999999998877777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (927 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       683  (0.0380947); expected 358.6 (0.02)
Passed bias filter:                      420  (0.0234257); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.74u 0.32s 00:00:01.06 Elapsed: 00:00:00.49
# Mc/sec: 5685.15
//
Query:       EEA22920.1  [L=1277]
Description: EF hand domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.8e-40  136.5   0.0      8e-17   61.1   0.0    3.4  3  EF-hand_4       Cytoskeletal-regulatory complex EF hand
    1.1e-07   30.8   0.1     0.0022   17.4   0.0    4.3  5  EF-hand_1       EF hand
    2.5e-07   30.4   0.0    4.5e-07   29.7   0.0    1.4  1  UBA             UBA/TS-N domain
    5.4e-07   30.0   0.0     0.0042   17.5   0.0    3.9  4  EF-hand_7       EF-hand domain pair
    8.8e-05   22.1   0.6       0.58   10.2   0.0    4.7  5  EF-hand_6       EF-hand domain
     0.0011   18.7   0.1       0.62   10.0   0.1    4.1  5  EF-hand_8       EF-hand domain pair
     0.0047   16.3  10.5     0.0047   16.3  10.5    2.8  3  DUF3450         Protein of unknown function (DUF3450)
  ------ inclusion threshold ------
      0.014   14.3  31.3        0.1   11.5  16.2    2.1  2  Spc7            Spc7 kinetochore protein
      0.016   14.6  25.6       0.06   12.7  12.5    2.3  2  GAS             Growth-arrest specific micro-tubule binding
        1.5    8.9  35.8        1.9    8.6  10.3    3.0  3  TPR_MLP1_2      TPR/MLP1/MLP2-like protein
        1.5    7.8  17.3        2.8    6.9  17.3    1.4  1  Atg14           Vacuolar sorting 38 and autophagy-related sub
        5.7    7.2  25.7       0.35   11.1   5.5    3.2  3  TMF_TATA_bd     TATA element modulatory factor 1 TATA binding


Domain annotation for each model (and alignments):
>> EF-hand_4  Cytoskeletal-regulatory complex EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.0     6e-09   8.9e-06       4      72 ..      11      80 ..       8      91 .. 0.93
   2 !   45.5   0.0   3.7e-15   5.6e-12       4      94 ..     138     228 ..     135     237 .. 0.92
   3 !   61.1   0.0   5.4e-20     8e-17       8      96 ..     289     377 ..     284     380 .. 0.90

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 6e-09
   EF-hand_4  4 leeleikkyweifsglkped.nkltgdkvapvlknskleedklekiwdladidedgkldfeefciamrli 72
                l + e+k ++++f++ + ++   +tg+++ p ++++kl+ d l  iw++ad ++ g l    f +++rli
  EEA22920.1 11 LTQEEKKVFFQLFQAADTTNlGVVTGEHAVPFFEKTKLPPDTLGLIWQIADKENRGLLTPSGFSMVLRLI 80
                6789999********999884689********************************************99 PP

  == domain 2  score: 45.5 bits;  conditional E-value: 3.7e-15
   EF-hand_4   4 leeleikkyweifsglkpednkltgdkvapvlknskleedklekiwdladidedgkldfeefciamrlifdlvngeikdvPselPewlvpe 94 
                 l+  + +k+  +f+  +     ++g+ + ++++ ++l+++ l +iw+l+d  + g+ld  ef+iam+l+  +  g ++ +P+ lP  l  +
  EEA22920.1 138 LNPEDANKFNSLFEKSDTPGGFMSGETAKQIFERARLPNEVLGRIWNLSDTKQRGQLDASEFIIAMHLLTSFKTGAMRVIPAALPAGLYEA 228
                 6677889999***************************************************************************988765 PP

  == domain 3  score: 61.1 bits;  conditional E-value: 5.4e-20
   EF-hand_4   8 eikkyweifsglkp.ednkltgdkvapvlknskleedklekiwdladidedgkldfeefciamrlifdlvngeikdvPselPewlvpesk 96 
                 e+ ++ +if +++  +   ++gd++ + + n++l+ed l++iwdladid dg+l  +ef++am l+   v g+ + +P++lP +l+p s 
  EEA22920.1 289 EKAQFDNIFATVDTaKAGIISGDQAVAFFTNAQLPEDVLAQIWDLADIDADGQLTKDEFAVAMYLVRQ-VRGKKEPLPATLPPALIPPSM 377
                 7778899**99986155789********************************************9976.79999*************885 PP

>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0       2.5   3.7e+03       4      19 ..      21      36 ..      19      38 .. 0.83
   2 ?   -1.0   0.0       1.2   1.7e+03       5      18 ..      56      69 ..      53      77 .. 0.89
   3 !    7.3   0.0    0.0025       3.7       4      27 ..     181     204 ..     178     206 .. 0.89
   4 ?   -1.2   0.0       1.3   1.9e+03       2      23 ..     293     314 ..     292     319 .. 0.75
   5 !   17.4   0.0   1.5e-06    0.0022       3      27 ..     328     352 ..     326     354 .. 0.91

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 2.5
                HHHHHHTTTSSSEEEH CS
   EF-hand_1  4 eiFrefDkDgdGkIdf 19
                ++F+ +D+ + G ++ 
  EEA22920.1 21 QLFQAADTTNLGVVTG 36
                78******99998885 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 1.2
                HHHHHTTTSSSEEE CS
   EF-hand_1  5 iFrefDkDgdGkId 18
                i++++Dk + G ++
  EEA22920.1 56 IWQIADKENRGLLT 69
                899******99988 PP

  == domain 3  score: 7.3 bits;  conditional E-value: 0.0025
                 HHHHHHTTTSSSEEEHHHHHHHHH CS
   EF-hand_1   4 eiFrefDkDgdGkIdfeEfkellk 27 
                 +i+++ D+ + G++d +Ef+ ++ 
  EEA22920.1 181 RIWNLSDTKQRGQLDASEFIIAMH 204
                 7999****************9996 PP

  == domain 4  score: -1.2 bits;  conditional E-value: 1.3
                 HHHHHHHHTTTSSSEEEHHHHH CS
   EF-hand_1   2 lkeiFrefDkDgdGkIdfeEfk 23 
                 +++iF+ +D+ + G I+ ++ +
  EEA22920.1 293 FDNIFATVDTAKAGIISGDQAV 314
                 899******9777777776655 PP

  == domain 5  score: 17.4 bits;  conditional E-value: 1.5e-06
                 HHHHHHHTTTSSSEEEHHHHHHHHH CS
   EF-hand_1   3 keiFrefDkDgdGkIdfeEfkellk 27 
                  +i++++D D dG+++++Ef  ++ 
  EEA22920.1 328 AQIWDLADIDADGQLTKDEFAVAMY 352
                 689******************9995 PP

>> UBA  UBA/TS-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.7   0.0     3e-10   4.5e-07       3      37 .]    1239    1273 ..    1237    1273 .. 0.93

  Alignments for each domain:
  == domain 1  score: 29.7 bits;  conditional E-value: 3e-10
                  HHHHHHHHHTTS-HHHHHHHHHHTTTSHHHHHHHH CS
         UBA    3 eeaiqrLveMGFdreevveALratgnNeErAveyL 37  
                     + rL  MGF+r+e + AL+  ++N++ A++yL
  EEA22920.1 1239 DLILKRLTGMGFPRDESLAALEKFDYNIDKAADYL 1273
                  56789*****************************9 PP

>> EF-hand_7  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.6   0.0      0.25   3.7e+02       3      62 ..      18      69 ..      11      78 .. 0.70
   2 ?    0.2   0.0      0.69     1e+03       7      35 ..      56      83 ..      51      96 .. 0.71
   3 ?    5.3   0.0     0.018        27       2      28 ..     177     206 ..     167     272 .. 0.78
   4 !   17.5   0.0   2.8e-06    0.0042       5      70 ..     294     351 ..     288     352 .. 0.86

  Alignments for each domain:
  == domain 1  score: 1.6 bits;  conditional E-value: 0.25
   EF-hand_7  3 klkeaFkelDtdgdgyldkee.llrllrkifqgagegsklsdeelellfkefDtdkdGvis 62
                + ++ F++ Dt + g ++ e  +  +++        + kl+++ l l+++  D+ + G ++
  EEA22920.1 18 VFFQLFQAADTTNLGVVTGEHaVP-FFE--------KTKLPPDTLGLIWQIADKENRGLLT 69
                456668888888888888887555.665........3445566788888888888888776 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.69
   EF-hand_7  7 aFkelDtdgdgyldkeellrllrkifqga 35
                +++  D+ ++g l+++ +  ++ +++ +a
  EEA22920.1 56 IWQIADKENRGLLTPSGFS-MVLRLIGHA 83
                57889**********9988.554455555 PP

  == domain 3  score: 5.3 bits;  conditional E-value: 0.018
   EF-hand_7   2 eklkeaFkelDtdgdgyldkeellr...ll 28 
                 e+l +++++ Dt ++g ld +e+     ll
  EEA22920.1 177 EVLGRIWNLSDTKQRGQLDASEFIIamhLL 206
                 567788888899999999999965433344 PP

  == domain 4  score: 17.5 bits;  conditional E-value: 2.8e-06
   EF-hand_7   5 keaFkelDtdgdgyldkeellrllrkifqgagegsklsdeelellfkefDtdkdGvisfdEFlkly 70 
                   +F   Dt + g ++ ++   +++        +  l+++ l ++++  D d dG+++ dEF  ++
  EEA22920.1 294 DNIFATVDTAKAGIISGDQAVAFFT--------NAQLPEDVLAQIWDLADIDADGQLTKDEFAVAM 351
                 5689999************554776........57778899*********************9888 PP

>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.0   0.0      0.76   1.1e+03       2      20 ..      19      37 ..      18      43 .. 0.89
   2 ?   -0.3   0.0      0.93   1.4e+03       6      29 ..      57      79 ..      55      81 .. 0.85
   3 ?    4.6   0.0     0.026        39       5      27 ..     182     204 ..     179     209 .. 0.85
   4 ?   -1.8   0.0       2.8   4.1e+03       2      27 ..     293     318 ..     292     320 .. 0.85
   5 !   10.2   0.0   0.00039      0.58       4      25 ..     329     350 ..     326     353 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.0 bits;  conditional E-value: 0.76
   EF-hand_6  2 lreaFklfDkdgdGkidae 20
                + ++F++ D+++ G ++ e
  EEA22920.1 19 FFQLFQAADTTNLGVVTGE 37
                6789********9999975 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.93
   EF-hand_6  6 FklfDkdgdGkidaeElrkalrka 29
                +++ Dk++ G ++++ +  +lr +
  EEA22920.1 57 WQIADKENRGLLTPSGFSMVLR-L 79
                5678***********9999998.5 PP

  == domain 3  score: 4.6 bits;  conditional E-value: 0.026
   EF-hand_6   5 aFklfDkdgdGkidaeElrkalr 27 
                 +++l D+   G++da+E++ a+ 
  EEA22920.1 182 IWNLSDTKQRGQLDASEFIIAMH 204
                 5677799999**********997 PP

  == domain 4  score: -1.8 bits;  conditional E-value: 2.8
   EF-hand_6   2 lreaFklfDkdgdGkidaeElrkalr 27 
                 ++ +F   D+ + G i+ ++ +++++
  EEA22920.1 293 FDNIFATVDTAKAGIISGDQAVAFFT 318
                 77899*******9***9999887776 PP

  == domain 5  score: 10.2 bits;  conditional E-value: 0.00039
   EF-hand_6   4 eaFklfDkdgdGkidaeElrka 25 
                 ++++l D d dG+++++E+  a
  EEA22920.1 329 QIWDLADIDADGQLTKDEFAVA 350
                 68999**************765 PP

>> EF-hand_8  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0       1.3   1.9e+03      30      44 ..      21      35 ..      14      38 .. 0.85
   2 ?   -3.4   0.0       6.3   9.5e+03       2      18 ..      65      81 ..      65      85 .. 0.84
   3 ?    1.0   0.0      0.25   3.8e+02      33      52 ..     184     203 ..     182     205 .. 0.87
   4 ?    1.1   0.0      0.23   3.5e+02      25      44 ..     290     309 ..     284     319 .. 0.88
   5 !   10.0   0.1   0.00042      0.62      33      53 ..     332     352 ..     316     353 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 1.3
   EF-hand_8 30 ilfrefDtdgdGkis 44
                 lf ++Dt + G+++
  EEA22920.1 21 QLFQAADTTNLGVVT 35
                59**********996 PP

  == domain 2  score: -3.4 bits;  conditional E-value: 6.3
   EF-hand_8  2 kgkItreelrrilrilg 18
                +g +t+  +++ lr++g
  EEA22920.1 65 RGLLTPSGFSMVLRLIG 81
                5899*******998886 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 0.25
   EF-hand_8  33 refDtdgdGkisfeEFcvll 52 
                 ++ Dt++ G ++  EF+  +
  EEA22920.1 184 NLSDTKQRGQLDASEFIIAM 203
                 578*************8665 PP

  == domain 4  score: 1.1 bits;  conditional E-value: 0.23
   EF-hand_8  25 eeevdilfrefDtdgdGkis 44 
                 + ++d +f ++Dt + G+is
  EEA22920.1 290 KAQFDNIFATVDTAKAGIIS 309
                 56799**************8 PP

  == domain 5  score: 10.0 bits;  conditional E-value: 0.00042
   EF-hand_8  33 refDtdgdGkisfeEFcvlle 53 
                 +++D+d dG ++++EF v + 
  EEA22920.1 332 DLADIDADGQLTKDEFAVAMY 352
                 689***************996 PP

>> DUF3450  Protein of unknown function (DUF3450)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   6.4      0.47     7e+02      14      58 ..     514     558 ..     494     563 .. 0.69
   2 !   16.3  10.5   3.1e-06    0.0047      15     108 ..     550     643 ..     547     650 .. 0.94
   3 ?   -1.1   0.9      0.62   9.2e+02      30      52 ..     663     685 ..     640     694 .. 0.59

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 0.47
     DUF3450  14 laatldqalkeaekavaaaaqsqkkidklddekqellaeyralke 58 
                 l++++ ++ ke ++ ++++a+++++ ++++++k++ +a++ ++++
  EEA22920.1 514 LSNQIGTLSKEMQNVQTKRAAAEQEFTQSSQQKRDFEARLAQARS 558
                 356666677777777777777777777777777777777776665 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 3.1e-06
     DUF3450  15 aatldqalkeaekavaaaaqsqkkidklddekqellaeyralkeeleslevyneqlerlvasqeqeiasleeqieeieeierelvpllekmidr 108
                 +a l+qa++  ek v+  ++ +++ +++  e+++l+++y  ++   ++l+ + eq ++ + + ++e asl+e+i +++   +el+p l+k  ++
  EEA22920.1 550 EARLAQARSMYEKEVKDFKALEERLNASRAETKKLQQDYALIEGSRQDLQNQYEQISAALVADQTENASLKEKIRQANVAVSELKPALDKARSD 643
                 57899999********************************************************************************997665 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 0.62
     DUF3450  30 aaaaqsqkkidklddekqellae 52 
                  ++ ++q +id+l++e+qe ++ 
  EEA22920.1 663 GERDKIQGEIDSLAKEAQETQEA 685
                 24556666666666666666544 PP

>> Spc7  Spc7 kinetochore protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   7.2   0.00054      0.81     198     260 ..     501     563 ..     495     569 .. 0.91
   2 ?   11.5  16.2   6.8e-05       0.1     144     252 ..     570     688 ..     567     695 .. 0.63

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00054
        Spc7 198 keeLeelreelaelkaeieekkkelaelqeqleeleekieelkeqkseleeeiaeaervleec 260
                  ++L +   ela+l+++i  ++ke++++q+++++ e+++++ ++qk+++e+++a+a++++e++
  EEA22920.1 501 AKKLTNETMELANLSNQIGTLSKEMQNVQTKRAAAEQEFTQSSQQKRDFEARLAQARSMYEKE 563
                 5778888899************************************************99975 PP

  == domain 2  score: 11.5 bits;  conditional E-value: 6.8e-05
        Spc7 144 leenlegleedkelLekqeeeldellpeleeekaeleeeleklqeaaeeles.........id.keeLeelreelaelkaeieekkkelaelqeqleel 232
                 lee+l++ +++ ++L+++ ++++   ++l+++++++++ l   q+++++l++         ++ k  L ++r++ +++k  ++  kk+la+++ +++++
  EEA22920.1 570 LEERLNASRAETKKLQQDYALIEGSRQDLQNQYEQISAALVADQTENASLKEkirqanvavSElKPALDKARSDARQQKGLVAINKKQLATVEGERDKI 668
                 677777777788888888888888888888888877777777777555544443322222244566667777777777777777777777777777777 PP

        Spc7 233 eekieelkeqkseleeeiae 252
                 + +i++l+++ +e++e+ + 
  EEA22920.1 669 QGEIDSLAKEAQETQEAAEL 688
                 77777777777766666543 PP

>> GAS  Growth-arrest specific micro-tubule binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7  12.5     4e-05      0.06      26     120 ..     516     607 ..     507     611 .. 0.84
   2 ?    7.5   5.0    0.0016       2.4      53     128 ..     613     685 ..     607     693 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 4e-05
         GAS  26 elIkslKeeieelkkkeernekelseisqenkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkelekelkdlkwehevleqrfekvek 120
                 + I +l +e+++ ++k +++e+e+ + sq++++ +  L +a+      +k++k+++   ++l++++a+ k+l++ +  ++ + + l+ ++e++++
  EEA22920.1 516 NQIGTLSKEMQNVQTKRAAAEQEFTQSSQQKRDFEARLAQARS---MYEKEVKDFKALEERLNASRAETKKLQQDYALIEGSRQDLQNQYEQISA 607
                 4688999999999999999999999999999999999998875...5678999999999999999999999999999999999999999998875 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0016
         GAS  53 sqenkrlkepLkkaeeeveeLrkqlknyekdkqslknlkarlkelekelkdlkwehevleqrfekvekerdelykk 128
                 ++en +lke++++a+  v eL+ +l + ++d    +++k  +   +k+l +++ e +  + +++++ ke +e ++ 
  EEA22920.1 613 QTENASLKEKIRQANVAVSELKPALDKARSD---ARQQKGLVAINKKQLATVEGERDKIQGEIDSLAKEAQETQEA 685
                 789********************99877765...556777777778889999999999999999999998888765 PP

>> TPR_MLP1_2  TPR/MLP1/MLP2-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6  10.3    0.0013       1.9      43     110 ..     502     569 ..     498     575 .. 0.91
   2 ?    8.6  14.6    0.0013       1.9      11     102 ..     568     659 ..     565     678 .. 0.88
   3 ?    2.4   1.1       0.1   1.5e+02      57      88 ..     656     687 ..     650     692 .. 0.65

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0013
  TPR_MLP1_2  43 qkYerelvkhaedvkelqalreelnelkaeiaelkaeaesakaeleeseesweeqkeelekelselek 110
                 +k  +e ++ a+ ++++ +l +e++++++++a +++e  + +++    e+ +++ ++++eke++++++
  EEA22920.1 502 KKLTNETMELANLSNQIGTLSKEMQNVQTKRAAAEQEFTQSSQQKRDFEARLAQARSMYEKEVKDFKA 569
                 5678999999*****************************************************99875 PP

  == domain 2  score: 8.6 bits;  conditional E-value: 0.0013
  TPR_MLP1_2  11 kslkeekeeaeaklqklqedlekqaeiakeaqqkYerelvkhaedvkelqalreelnelkaeiaelkaeaesakaeleeseesweeqkeele 102
                 k+l+e+ ++++a+ +klq+d    + + ++ q++Ye+      +d +e ++l+e++ +++  ++elk ++++a+++  +++   +  k++l 
  EEA22920.1 568 KALEERLNASRAETKKLQQDYALIEGSRQDLQNQYEQISAALVADQTENASLKEKIRQANVAVSELKPALDKARSDARQQKGLVAINKKQLA 659
                 7899*****************************************************************************99988888874 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.1
  TPR_MLP1_2  57 kelqalreelnelkaeiaelkaeaesakaele 88 
                 k+l+++  e ++++ ei +l +ea++++++ e
  EEA22920.1 656 KQLATVEGERDKIQGEIDSLAKEAQETQEAAE 687
                 56666666666777777777776666666554 PP

>> Atg14  Vacuolar sorting 38 and autophagy-related subunit 14
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9  17.3    0.0019       2.8      21     160 ..     515     687 ..     496     726 .. 0.84

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0019
       Atg14  21 perlyelrerlaklksekeslkkkiekalegke.........................eaeqledkiknkkakleelksliadlrerlqelkdklsqlk 94 
                 ++++ +l ++++++++++++ ++++++  ++k+                         + + ++++ k+++++  ++   ++dl+++ +++++ l   +
  EEA22920.1 515 SNQIGTLSKEMQNVQTKRAAAEQEFTQSSQQKRdfearlaqarsmyekevkdfkaleeRLNASRAETKKLQQDYALIEGSRQDLQNQYEQISAALVADQ 613
                 458899999999999999999999999999999999999999999999999999888777777788888888888888888888888999999999999 PP

       Atg14  95 keieekkkklaklsdklk.......kRrsdleslqneleerrkkqiaklqdaikrieqklsslssktles..rss 160
                  e++  k+k+++ + +++       k rsd +  q+ l +  kkq+a++  +  +i+  ++sl ++ +e+   ++
  EEA22920.1 614 TENASLKEKIRQANVAVSelkpaldKARSD-ARQQKGLVAINKKQLATVEGERDKIQGEIDSLAKEAQETqeAAE 687
                 999999999999999999999999788888.889**************************999999999855333 PP

>> TMF_TATA_bd  TATA element modulatory factor 1 TATA binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   5.5   0.00023      0.35      47     114 ..     499     566 ..     495     567 .. 0.95
   2 ?    0.5   3.5      0.47     7e+02      17      77 ..     570     634 ..     566     642 .. 0.65
   3 ?    7.1   1.6    0.0041       6.1      19      67 ..     642     690 ..     634     695 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00023
  TMF_TATA_bd  47 eeivklmkeneelkelkkeleelekeleelqeryetlLellGeksEeveELraDvaDlKemykeqveq 114
                  ee  kl++e+ el++l++++ +l+ke++++q++  ++ + + + s +  + +a +a  + my++ v++
   EEA22920.1 499 EEAKKLTNETMELANLSNQIGTLSKEMQNVQTKRAAAEQEFTQSSQQKRDFEARLAQARSMYEKEVKD 566
                  67889**********************************************************99975 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.47
  TMF_TATA_bd  17 lsseirrlEgElaslkeelerleaerdeareei....vklmkeneelkelkkeleelekeleelq 77 
                  l+ ++    +E ++l+++++ +e +r++++++     ++l+++  e+++lk+++++ +  ++el+
   EEA22920.1 570 LEERLNASRAETKKLQQDYALIEGSRQDLQNQYeqisAALVADQTENASLKEKIRQANVAVSELK 634
                  66667777788888888888888888877765411114455666666677777777666666665 PP

  == domain 3  score: 7.1 bits;  conditional E-value: 0.0041
  TMF_TATA_bd  19 seirrlEgElaslkeelerleaerdeareeivklmkeneelkelkkele 67 
                  s  r+  g +a  k++l+++e erd+++ ei +l ke +e++e+++  +
   EEA22920.1 642 SDARQQKGLVAINKKQLATVEGERDKIQGEIDSLAKEAQETQEAAELTR 690
                  6678888889999************************999999877655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1277 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1653  (0.092197); expected 358.6 (0.02)
Passed bias filter:                      592  (0.0330191); expected 358.6 (0.02)
Passed Vit filter:                        99  (0.00552178); expected 17.9 (0.001)
Passed Fwd filter:                        44  (0.00245412); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 1.33u 0.33s 00:00:01.66 Elapsed: 00:00:00.56
# Mc/sec: 6855.32
//
Query:       EEA22921.1  [L=450]
Description: tubulin alpha-1 subunit [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    7.6e-67  225.3   0.0    1.2e-66  224.7   0.0    1.3  1  Tubulin    Tubulin/FtsZ family, GTPase domain
    7.1e-50  168.4   0.1    1.3e-49  167.6   0.1    1.5  1  Tubulin_C  Tubulin C-terminal domain
     0.0012   18.5   0.0     0.0029   17.3   0.0    1.6  1  Tubulin_3  Tubulin domain


Domain annotation for each model (and alignments):
>> Tubulin  Tubulin/FtsZ family, GTPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  224.7   0.0     2e-70   1.2e-66       1     196 [.       3     213 ..       3     214 .. 0.99

  Alignments for each domain:
  == domain 1  score: 224.7 bits;  conditional E-value: 2e-70
                 EEEEEEEHHHHHHHHHHHHH...HHHCH................HHHT.....TTEEEEE....EEESBHHHHHTS-GS........EEEE--CCCCTT CS
     Tubulin   1 eiivigvGqcGnqignelwellakehgiqsdg............dslesfFsesgkveyiprsvaidtdpqvlneikags..elfnpnklllgkegagn 85 
                 e+i ++vGq+G+qi+n++wel++ ehgiq+dg            + +++fFse+g+++y+pr++ +d++p+v++e+++g+  +lf+p+++++gke+a+n
  EEA22921.1   3 EVISLNVGQAGCQIANSCWELYCLEHGIQPDGylteerkaqepdEGFSTFFSETGQGKYVPRTIYCDLEPNVVDEVRTGTyrSLFHPEQMVTGKEDASN 101
                 799*****************************************9****************************************************** PP

                 C--TT-HHHHHHHHHHTHHHHHHHHTT-SE.SEEEEEEETTSSHHHHHHHHHHHHHHHTSTTSEEEEEEEE--.GG.G-HHHHHHHHHHHHHHHHT-SE CS
     Tubulin  86 ngaggypevgkeaaeeileeirkevekcdslqgffitaslgGGTGSGlgpvilevlkeeypkalvvtvvvlPs.efsevvvepynailalkelieesda 183
                 n+a+g+++vgke+++ +l+++r+ +++c  lqgf++++s+gGGTGSG+g++++e+l+ +y k+ ++ ++v+P  ++ ++vvepyn+il++++  e+sd+
  EEA22921.1 102 NYARGHYTVGKEMIDRVLDQVRRVADNCSGLQGFLVFHSFGGGTGSGFGALLMERLSVDYGKKSKLEFCVYPApQNATSVVEPYNSILTTHTTLEHSDC 200
                 **************************************************************************999********************** PP

                 EEEEEHHHHHCCS CS
     Tubulin 184 vividNdaLlkil 196
                  +++dN+a+++i+
  EEA22921.1 201 SFMVDNEAIYDIC 213
                 ************9 PP

>> Tubulin_C  Tubulin C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  167.6   0.1   2.2e-53   1.3e-49       1     125 [.     263     392 ..     263     393 .. 0.99

  Alignments for each domain:
  == domain 1  score: 167.6 bits;  conditional E-value: 2.2e-53
                 TTC-EEEEEEESSSCTTTTTCS-HHHHHHHHHTCSGGGBSSSTSTTTSSEEEEEEEEEESSSHHHHHHHHHHHHHTTTS-BSTTSTTTEEEEEEECECT CS
   Tubulin_C   1 PrlhFlltsyaPlvsaekaavektsvqdvtrallepknimvkvdprkgkylaiallirGdvepkevnkavqrikekkkaqfveWiptgikvalnkkspy 99 
                 Pr+hF+l++yaP++sa+k+ +e +sv+++t +++ep+n+mvk+dpr+gky+a++ll+rGdv+pke ++av+++k+k+++qfv+W+ptg+k+++++++p+
  EEA22921.1 263 PRIHFPLVAYAPVISAAKSLHEANSVNEITMSCFEPNNQMVKCDPRNGKYMATCLLYRGDVVPKETHAAVATLKTKRTIQFVDWCPTGFKIGICYQPPQ 361
                 9************************************************************************************************** PP

                 -TTTS.....SCEEEEEEEEGGGHHHHHHHH CS
   Tubulin_C 100 vkkqs.....kvsvlmlaNttsiaelfkrll 125
                 ++++      +++v+ml+Ntt+iae+++ l+
  EEA22921.1 362 MVPNGdlakvNRAVCMLSNTTAIAEAWSALD 392
                 ****99**999****************9886 PP

>> Tubulin_3  Tubulin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0   4.8e-07    0.0029      58     108 ..     113     167 ..      82     202 .. 0.78

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 4.8e-07
   Tubulin_3  58 dlldr...dlrpfaeecdqlrglqvftgvddaWG.Gfaakylerlrdeygkksil 108
                 +++dr    +r  a++c  l+g+ vf +     G Gf+a  +erl  +ygkks l
  EEA22921.1 113 EMIDRvldQVRRVADNCSGLQGFLVFHSFGGGTGsGFGALLMERLSVDYGKKSKL 167
                 344443325899****************99887769****************954 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (450 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       416  (0.0232026); expected 358.6 (0.02)
Passed bias filter:                      370  (0.020637); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 2956.29
//
Query:       EEA22922.1  [L=279]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.7e-06   26.6   0.0    9.7e-06   25.6   0.0    1.5  1  Pga1      GPI-Mannosyltransferase II co-activator
  ------ inclusion threshold ------
      0.013   14.1   0.2       0.02   13.5   0.2    1.2  1  FPN1      Ferroportin1 (FPN1)
      0.029   14.3   1.0      0.064   13.2   1.0    1.5  1  PsbI      Photosystem II reaction centre I protein (PSII 4.8 
       0.13   12.3   0.4       0.28   11.2   0.4    1.6  1  TM_helix  Conserved TM helix


Domain annotation for each model (and alignments):
>> Pga1  GPI-Mannosyltransferase II co-activator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.0   2.2e-09   9.7e-06       2     101 ..      13     111 ..      12     126 .. 0.76

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 2.2e-09
        Pga1   2 lflvalvlANTEtfllkvPkdFplienrdeltrevaesnktlisLedsniakktyntkvkpk.ktllielndlksdetyqvkicWtAidPisikdldhl 99 
                 l++++ + ANTE   +  P  + +  ++ +  +   +  ++   +  +n++   + t+ +p+ ++    l+dl +++ y+v+icW A++P s++ l + 
  EEA22922.1  13 LLFIQHAAANTEKTIFVAPLPWAVPAENAAIDDLGLDRLSPTDFMLRTNLN-ASFPTDEEPHgAESWFYLEDLTPGQRYEVRICWMATQPTSFD-LTTY 109
                 567888999999999999998888666666677777777777777777764.55666655552567889************************9.5544 PP

        Pga1 100 vv 101
                 ++
  EEA22922.1 110 TL 111
                 43 PP

>> FPN1  Ferroportin1 (FPN1)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   0.2   4.5e-06      0.02      28      65 ..     223     260 ..     213     268 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 4.5e-06
        FPN1  28 flaeLypnsLllvavyglveslsvlllgaivGklvdkl 65 
                 fl +++p+sL+++avy +v ++++ ++g ++ k+++ +
  EEA22922.1 223 FLWNVFPRSLVPTAVYTVVIAVVAYFVGGYLAKVLSDV 260
                 8999**************************99998765 PP

>> PsbI  Photosystem II reaction centre I protein (PSII 4.8 kDa protein)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.2   1.0   1.4e-05     0.064       7      25 ..     236     254 ..     235     255 .. 0.93

  Alignments for each domain:
  == domain 1  score: 13.2 bits;  conditional E-value: 1.4e-05
        PsbI   7 vVyivViffvslFvFGfLs 25 
                 +Vy+vVi++v+ Fv G+L+
  EEA22922.1 236 AVYTVVIAVVAYFVGGYLA 254
                 6***************996 PP

>> TM_helix  Conserved TM helix
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.4   6.2e-05      0.28      16      40 ..     239     263 ..     231     267 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 6.2e-05
                 HHHHHHHHHHHHHHHHHHHHHHHHH CS
    TM_helix  16 nLvgAilILlvGwiiAkfvsrlvtk 40 
                  +v+A++  +vG ++Ak++s++v+ 
  EEA22922.1 239 TVVIAVVAYFVGGYLAKVLSDVVKA 263
                 5677888888888888888888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (279 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       542  (0.0302304); expected 358.6 (0.02)
Passed bias filter:                      391  (0.0218082); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.40
# Mc/sec: 2082.05
//
Query:       EEA22923.1  [L=637]
Description: DNA directed RNA polymerase III subunit Rpc82, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.6e-28  100.2   0.1    1.2e-27   97.3   0.0    2.2  2  RNA_pol_Rpc82  RNA polymerase III subunit RPC82
    9.7e-15   54.4   5.9    4.3e-10   39.5   0.4    3.4  3  HTH_9          RNA polymerase III subunit RPC82 helix-turn-he
      2e-09   37.2   0.2    0.00033   20.5   0.1    2.8  2  TFIIE_alpha    TFIIE alpha subunit
      1e-05   25.3   0.1       0.34   10.8   0.0    3.3  3  TrmB           Sugar-specific transcriptional regulator TrmB
  ------ inclusion threshold ------
      0.018   15.0   1.3        1.6    8.7   0.2    3.4  3  MarR           MarR family
      0.042   14.4   1.1         17    6.0   0.3    4.0  4  ANAPC2         Anaphase promoting complex (APC) subunit 2
       0.28   10.8   3.0        2.1    8.0   0.1    3.2  4  SMC_ScpB       Segregation and condensation complex subunit S
       0.31   10.9   2.1        7.6    6.5   0.2    3.2  3  HxlR           HxlR-like helix-turn-helix


Domain annotation for each model (and alignments):
>> RNA_pol_Rpc82  RNA polymerase III subunit RPC82
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.1   0.0      0.25   5.5e+02     105     138 ..      77     110 ..      37     111 .. 0.82
   2 !   97.3   0.0   5.3e-31   1.2e-27       3     258 .]     184     470 ..     182     470 .. 0.81

  Alignments for each domain:
  == domain 1  score: 0.1 bits;  conditional E-value: 0.25
                    EE-SHHHHHHHHHHHHHHHHHHHS-SHHHHHHHH CS
  RNA_pol_Rpc82 105 riNlerflvhlRdeaLvqlaksrigettaevyea 138
                     +N++      R+    + +++r+g+ +a+v++a
     EEA22923.1  77 EANIDGAYYLIRTGKVLEVVEERLGSYAAQVMAA 110
                    5555555566788889999************986 PP

  == domain 2  score: 97.3 bits;  conditional E-value: 5.3e-31
                    HHHHHTTSSEEESSSTTTS-HHHHHHHHHHHTHTTSSSSSSSSTHHHHHHHHHHHHHHHHHHHHHHHSGT...........T..TTCETSSSSSEE CS
  RNA_pol_Rpc82   3 fvkLveagflqrvpslhfrpiedlwnalyeeelkktprssttseikkkaeakekiktelrdlresseslkkkeg.......rstadstsngtarKr 91 
                    +  L+  g++ +v+++h+++++d +   ++e++     +s  ++ kk ae ++k ++ l+d ++   s     +       r++++ +s++  ++r
     EEA22923.1 184 LNYLAGHGYICQVKDVHLHSLADNTLDAEREATIWAG-NSDSKGKKKAAEIEDKKREILNDRLDADLSRGLTAYahppvtkRRQENGHSENPHKRR 278
                    6678999**************9987666666665554.5666666666777777777777777777776544447777776666666555555444 PP

                    ........................E-TSSEEEE-SHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHTSTSS-GSS-TTS....HHHHHHTTTC CS
  RNA_pol_Rpc82  92 rk..................etealdpglvlriNlerflvhlRdeaLvqlaksrigettaevyeaaLklleersprlsadll....leeedkksit 165
                    r                   ++e   p+lv+r+N++++ v +R+++Lv+la + +   taevye++L+l+e ++p +++        ee +++s+ 
     EEA22923.1 279 RVdsddemgdentwdegdveDQETMRPTLVVRVNYQKLDVVFRNRRLVELALQGTSPATAEVYETLLRLIEYKTPCCREGIEipreGEEGETNSVA 374
                    448*****************************************************************************8899*99********* PP

                    SCSSTHHHH-STT-------.....-------------.-----...--------------HHHHHHHHHHHHHSSSSSSCSEET...TEBE-SST CS
  RNA_pol_Rpc82 166 ftandiaralpksldlsksi.....gKrkssnssaaek.kklkt...eeseeeseengqarlslieqhLklLasdsleflrkigpsggGeytVdfs 252
                    +t++ +a +++ +ldl+++i     ++++++n+ ++++         +e+++++e +   r+  i+qhL lLa  + ++ ++ ++     ++V+++
     EEA22923.1 375 ITLQRLANEVDPRLDLKGTIgppgnPQASKTNKRSLANgV---NgihHEDDDDTETT---RTHEIDQHLNLLALPPYSLSTRRSQGTIPAWYVEYR 464
                    ********************65433222244444444443...24536655555555...899*************99999999988889****** PP

                    TTHHHH CS
  RNA_pol_Rpc82 253 rlieqL 258
                    rl +qL
     EEA22923.1 465 RLARQL 470
                    ***998 PP

>> HTH_9  RNA polymerase III subunit RPC82 helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.5   0.4   1.9e-13   4.3e-10       1      57 [.       7      63 ..       7      67 .. 0.97
   2 ?    3.7   0.0     0.031        69       4      33 ..      93     122 ..      91     131 .. 0.83
   3 !   12.3   0.3   6.2e-05      0.14       7      58 ..     479     530 ..     475     532 .. 0.92

  Alignments for each domain:
  == domain 1  score: 39.5 bits;  conditional E-value: 1.9e-13
                HHHHHHHHHCSTTHHHHHHHHHHHHSSBEHHHHHHHHSSTHHHHHHHHHHHHHTTSE CS
       HTH_9  1 elcteiieehFGevvakVvetLlrkgrltlrelvkktkLsldqVkksLvvLiqhrlV 57
                elct+++e+ FG++  ++++tL+++grltl  l   +++s +q  ++L++L+q +lV
  EEA22923.1  7 ELCTLLVEDNFGDLFGRIYSTLVQYGRLTLFRLRDHSQVSQKQLLHALAALVQMHLV 63
                69******************************************************9 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.031
                 HHHHHHCSTTHHHHHHHHHHHHSSBEHHHH CS
       HTH_9   4 teiieehFGevvakVvetLlrkgrltlrel 33 
                  e++ee +G+ +a+V+  +  +g   ++el
  EEA22923.1  93 LEVVEERLGSYAAQVMAAIAYHGHIMISEL 122
                 689**************9998887666665 PP

  == domain 3  score: 12.3 bits;  conditional E-value: 6.2e-05
                 HHHCSTTHHHHHHHHHHHHSSBEHHHHHHHHSSTHHHHHHHHHHHHHTTSEE CS
       HTH_9   7 ieehFGevvakVvetLlrkgrltlrelvkktkLsldqVkksLvvLiqhrlVq 58 
                 +   FG+++ +V++ Ll+ g+l  + l++ + +s +  +++L+ ++ +++V+
  EEA22923.1 479 VGIRFGKLALRVIQILLSMGKLDEKRLQEVSLISQKDLRQVLAQMQENGFVD 530
                 5556*************************999*************9999995 PP

>> TFIIE_alpha  TFIIE alpha subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.8   0.0   1.7e-05     0.038       2      92 ..       8     103 ..       7     115 .. 0.86
   2 !   20.5   0.1   1.5e-07   0.00033       4      62 ..     476     534 ..     474     578 .. 0.85

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 1.7e-05
                  HHHHHHHHCS-HHHHHHHHHHHCTTSEBHHHHHHHHTS-HHHHHHHHHHHHHCTSEEEEEEEE.....TTTEEEEEEEEEECCCHCCCHHHHHHHH CS
  TFIIE_alpha   2 llkevvrkfygeeavlvldvLlekgevteedlakelkidlnelrklLnrLyearlvkykrrrd.....eekswykyywrinyeklvdvvkrkleev 92 
                  l   +v   +g+ +  +   L++ g +t   l  + ++ +++l ++L++L +  lv    + d      e ++   y++i   k+++vv ++l   
   EEA22923.1   8 LCTLLVEDNFGDLFGRIYSTLVQYGRLTLFRLRDHSQVSQKQLLHALAALVQMHLVYHYTSTDdgftyYEANIDGAYYLIRTGKVLEVVEERLGSY 103
                  6677899999999*******************************************99999993444445555568*************9998665 PP

  == domain 2  score: 20.5 bits;  conditional E-value: 1.5e-07
                  HHHHHHCS-HHHHHHHHHHHCTTSEBHHHHHHHHTS-HHHHHHHHHHHHHCTSEEEEEE CS
  TFIIE_alpha   4 kevvrkfygeeavlvldvLlekgevteedlakelkidlnelrklLnrLyearlvkykrr 62 
                  + +v+  +g+ a  v+++Ll+ g++ e  l++   i ++ lr++L++++e ++v+ +  
   EEA22923.1 476 ERIVGIRFGKLALRVIQILLSMGKLDEKRLQEVSLISQKDLRQVLAQMQENGFVDLQEI 534
                  56888899999********************************************9764 PP

>> TrmB  Sugar-specific transcriptional regulator TrmB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.8   0.0   0.00015      0.34      12      58 ..      23      69 ..      20      79 .. 0.88
   2 ?   -0.8   0.0      0.65   1.5e+03      11      23 ..     338     350 ..     332     364 .. 0.65
   3 !   10.1   0.0   0.00026      0.59      12      57 ..     489     534 ..     483     546 .. 0.90

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00015
                CHCHHHHHHCCCHHCHHCCCTTSSCHCHHHHHHHHHHCTSEEEESST CS
        TrmB 12 kvYlaLlklgpatadeiaeelgvprskvYevLrsLedkGlVerekgr 58
                ++Y +L+++g++t   +  ++ v++ +   +L  L+++ lV+   ++
  EEA22923.1 23 RIYSTLVQYGRLTLFRLRDHSQVSQKQLLHALAALVQMHLVYHYTST 69
                68***************************************987666 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.65
                 CCHCHHHHHHCCC CS
        TrmB  11 akvYlaLlklgpa 23 
                 a+vY +Ll+l + 
  EEA22923.1 338 AEVYETLLRLIEY 350
                 7788888876555 PP

  == domain 3  score: 10.1 bits;  conditional E-value: 0.00026
                 CHCHHHHHHCCCHHCHHCCCTTSSCHCHHHHHHHHHHCTSEEEESS CS
        TrmB  12 kvYlaLlklgpatadeiaeelgvprskvYevLrsLedkGlVerekg 57 
                 +v + Ll+ g+++ + + e + +++    +vL ++ + G+V+ ++ 
  EEA22923.1 489 RVIQILLSMGKLDEKRLQEVSLISQKDLRQVLAQMQENGFVDLQEI 534
                 56678************************************98865 PP

>> MarR  MarR family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0     0.068   1.5e+02      12      55 ..      28      71 ..      23      72 .. 0.84
   2 ?    8.7   0.2    0.0007       1.6       6      55 ..     488     537 ..     486     540 .. 0.94
   3 ?   -0.1   0.0       0.4   8.9e+02       1      25 [.     602     626 ..     602     630 .. 0.92

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.068
                HHHSTTEEHHHHHHHHTS-HHHHHHHHHHHHHTTSEEEEEETTS CS
        MarR 12 lyeqgplsvseLakklgvskstvtrvldrLekkGlieRskspeD 55
                l + g l++  L ++++vs+  +  +l +L++  l++ + s++D
  EEA22923.1 28 LVQYGRLTLFRLRDHSQVSQKQLLHALAALVQMHLVYHYTSTDD 71
                66778888888889999999999999999999999999999998 PP

  == domain 2  score: 8.7 bits;  conditional E-value: 0.0007
                 HHHHHHHHHSTTEEHHHHHHHHTS-HHHHHHHHHHHHHTTSEEEEEETTS CS
        MarR   6 fviLrilyeqgplsvseLakklgvskstvtrvldrLekkGlieRskspeD 55 
                 ++++ il ++g l  + L++ + +s+  +  vl ++ ++G+++ +  p+D
  EEA22923.1 488 LRVIQILLSMGKLDEKRLQEVSLISQKDLRQVLAQMQENGFVDLQEIPKD 537
                 5789999***********************************99999998 PP

  == domain 3  score: -0.1 bits;  conditional E-value: 0.4
                 --HHHHHHHHHHHHSTTEEHHHHHH CS
        MarR   1 ltltqfviLrilyeqgplsvseLak 25 
                 lt++++++Lr+ +e+++l + e+a+
  EEA22923.1 602 LTEAELETLRQWREKEGLMLGEIAR 626
                 899*******************997 PP

>> ANAPC2  Anaphase promoting complex (APC) subunit 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.38   8.6e+02      28      51 ..      40      63 ..      21      68 .. 0.78
   2 ?   -1.0   0.0       1.1   2.5e+03      15      38 ..     178     199 ..     176     202 .. 0.83
   3 ?    6.0   0.3    0.0075        17      30      52 ..     507     530 ..     483     533 .. 0.77
   4 ?    2.2   0.0      0.12   2.6e+02      18      46 ..     562     590 ..     559     600 .. 0.83

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.38
      ANAPC2 28 degydisdeeLkefLdelvkegkL 51
                 ++ ++s+++L + L  lv+ + +
  EEA22923.1 40 RDHSQVSQKQLLHALAALVQMHLV 63
                456789************998876 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 1.1
      ANAPC2  15 eRIhsmLkmfvpkdegydisdeeL 38 
                  R+hs L+ ++   +gy ++ +++
  EEA22923.1 178 TRLHSALNYLA--GHGYICQVKDV 199
                 59********9..88998887765 PP

  == domain 3  score: 6.0 bits;  conditional E-value: 0.0075
      ANAPC2  30 gyd.isdeeLkefLdelvkegkLe 52 
                 +++ is+++L+++L +++++g ++
  EEA22923.1 507 EVSlISQKDLRQVLAQMQENGFVD 530
                 56669**************99776 PP

  == domain 4  score: 2.2 bits;  conditional E-value: 0.12
      ANAPC2  18 hsmLkmfvpk.degydisdeeLkefLdelv 46 
                 h ++k ++ +  +   ++ ++Lk+fLd+  
  EEA22923.1 562 HDTYKAMS-RcIQRLRFERTRLKDFLDKTE 590
                 77788887.55888999**********875 PP

>> SMC_ScpB  Segregation and condensation complex subunit ScpB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   0.1   0.00093       2.1      54     106 ..      81     125 ..      28     132 .. 0.63
   2 ?   -1.5   0.0      0.77   1.7e+03      89     105 ..     345     361 ..     329     370 .. 0.80
   3 ?    1.1   0.1      0.12   2.7e+02      12      40 ..     498     526 ..     490     539 .. 0.79
   4 ?   -3.5   0.0       3.1   6.9e+03      77      89 ..     598     610 ..     590     612 .. 0.80

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.00093
    SMC_ScpB  54 aggyrlvtkpelaevvkklvkekkktrLsqaaletLaiIaykqpvtraeieei 106
                 +g y l    ++ ev         ++rL + a +++a Iay+  ++ +e+e++
  EEA22923.1  81 DGAYYLIRTGKVLEV--------VEERLGSYAAQVMAAIAYHGHIMISELEAL 125
                 455555544444433........34588889***************9999986 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.77
    SMC_ScpB  89 LaiIaykqpvtraeiee 105
                 L +I yk p+ r+ ie 
  EEA22923.1 345 LRLIEYKTPCCREGIEI 361
                 6799********99985 PP

  == domain 3  score: 1.1 bits;  conditional E-value: 0.12
    SMC_ScpB  12 eplsleeLakilelskeeveealeeLkee 40 
                  +l+ ++L+++  +s+++++++l++++e+
  EEA22923.1 498 GKLDEKRLQEVSLISQKDLRQVLAQMQEN 526
                 56778888888888888888888888875 PP

  == domain 4  score: -3.5 bits;  conditional E-value: 3.1
    SMC_ScpB  77 kktrLsqaaletL 89 
                 +++ L++a+letL
  EEA22923.1 598 EEKYLTEAELETL 610
                 5788999999998 PP

>> HxlR  HxlR-like helix-turn-helix
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.0   0.0      0.36   8.2e+02      29      51 ..      43      65 ..      28     110 .. 0.74
   2 ?    1.5   0.1      0.12   2.7e+02      33      49 ..     463     479 ..     453     499 .. 0.87
   3 ?    6.5   0.2    0.0034       7.6      19      60 ..     503     540 ..     484     545 .. 0.75

  Alignments for each domain:
  == domain 1  score: -0.0 bits;  conditional E-value: 0.36
                TTS-HHHHHHHHHHHHHTTSEEE CS
        HxlR 29 pkisqkmLaqrLreLeqdglier 51
                 ++sqk L + L +L q +l+  
  EEA22923.1 43 SQVSQKQLLHALAALVQMHLVYH 65
                58999999999999999888854 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.12
                 HHHHHHHHHHHHHTTSE CS
        HxlR  33 qkmLaqrLreLeqdgli 49 
                  + La++Lr+Le ++++
  EEA22923.1 463 YRRLARQLRHLEIERIV 479
                 5789*********9998 PP

  == domain 3  score: 6.5 bits;  conditional E-value: 0.0034
                 EEHHHHHHHSTTS-HHHHHHHHHHHHHTTSEEEEEESSSS-E CS
        HxlR  19 kRfselkralpkisqkmLaqrLreLeqdglierevypevPpk 60 
                 kR +e    +  isqk L q L +++++g+++ +++p+  ++
  EEA22923.1 503 KRLQE----VSLISQKDLRQVLAQMQENGFVDLQEIPKDAQR 540
                 33333....4579*******************9999988766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (637 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       770  (0.0429472); expected 358.6 (0.02)
Passed bias filter:                      549  (0.0306208); expected 358.6 (0.02)
Passed Vit filter:                        69  (0.00384851); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.65u 0.33s 00:00:00.98 Elapsed: 00:00:00.48
# Mc/sec: 3974.51
//
Query:       EEA22924.1  [L=460]
Description: ubiquinol-cytochrome C reductase complex core protein 2, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.2e-15   57.8   0.1    2.1e-15   57.0   0.1    1.4  1  Peptidase_M16    Insulinase (Peptidase family M16)
    4.8e-12   46.2   0.0    9.7e-12   45.3   0.0    1.5  1  Peptidase_M16_C  Peptidase M16 inactive domain


Domain annotation for each model (and alignments):
>> Peptidase_M16  Insulinase (Peptidase family M16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.0   0.1   2.3e-19   2.1e-15       9     139 ..      52     180 ..      45     189 .. 0.92

  Alignments for each domain:
  == domain 1  score: 57.0 bits;  conditional E-value: 2.3e-19
                    SSSEEEEEEEES-SGGGSCTTTTTHHHHHHHHTTSBBSSSCHHHHHHHHHHTTCEEEEEEESSEEEEEEEEEGGGHHHHHHHHHHHHHSBTTSHHH CS
  Peptidase_M16   9 paktsavglvvdaGSryepkdlnGlAHllehmafkgTkkypsnklaeeleklGgslnAttsrentvYyvevlskdlekaldvladvfkaplleese 104
                    +  ts +++v +aGSryep   +G +  l + af++T k+++ ++++e+e lG +l A  +ren v ++++ls dl++  ++la+v+ +++ +  e
     EEA22924.1  52 EGATSLLAVVAKAGSRYEPV--PGFSDALARYAFQSTYKRSGLRITREAELLGSNLTAKNTRENVVLQAKFLSADLPYFAELLAEVTSQTKYNAYE 145
                    567999************96..5************************************************************************* PP

                    HHHHHH.HHHHHHHHHCCHHHHHHHHHHHHHHTTTS CS
  Peptidase_M16 105 vererk.vvekeveavdaepekvveenlhaaayrek 139
                      + ++ +++ + +++ ++pe +++e+ ha+a+  +
     EEA22924.1 146 WAELVLpTIKLRQQVLFSKPEILALESAHATAFH-R 180
                    ***999899999999999999999*******997.4 PP

>> Peptidase_M16_C  Peptidase M16 inactive domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   45.3   0.0   1.1e-15   9.7e-12       2     180 ..     198     378 ..     197     380 .. 0.92

  Alignments for each domain:
  == domain 1  score: 45.3 bits;  conditional E-value: 1.1e-15
                      H-HHHHHHHHHHHSSGGGEEEEEEESS-HHHHHHHHHHHHTTSTHHSHCSGSCTSSSSSGGGSSEEEEEEEESSSSSEEEEEEEEEECTCTHTT CS
  Peptidase_M16_C   2 ltredlkefykkfYrpenmvlaivGdvdheelvkliekyfgdlkaskappakptgepltpatlkkppvvlkkldeeqahlslafegpskended 95 
                      +t + l ef ++ Y   n+ l+ vG  +  e+ k++ ++f + +a +   ++ ++++  p ++ +++ +   +    + + + f+g +++    
       EEA22924.1 198 FTEDGLAEFAQSAYAKPNISLVSVG-PNSSEVSKWVGQFFAGHPAGA-AAGQFKVKDTVPSKFYGGEQRTASKA--GNTIVISFPGSAQYGASG 287
                      788999*******************.5555**************997.889999999999999**********9..99999*******977666 PP

                      HHH.HHHHHHHHHSS......TTSHHHHHHHTTTTSESEEEEEEEEESSCEEEEEEEEEECTTHHHHHHHHHHHHHHHHHHTS-HHHHHHHH CS
  Peptidase_M16_C  96 dla.lavlntlLggg......mesrLytnlrekeglaysvsafndsyrdsglfgisatadpenveevvevilkelrklkkeglteeelerak 180
                      + a  +vl+ lLgg+      + ++L  +   ++  + svs  n  y+d glf ++++++ + v+ v + + +++++++  +++ e +++a+
       EEA22924.1 288 YKAeADVLAALLGGEstikwsPGFSLLAKAA-ESETGVSVSTKNYAYSDAGLFAVTVSGKADSVATVAKRAAEAIKQVAAGEIPAEVVKKAI 378
                      654389***************9999999999.888899***********************************************9999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (460 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       475  (0.0264934); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.51u 0.26s 00:00:00.77 Elapsed: 00:00:00.42
# Mc/sec: 3293.57
//
Query:       EEA22925.1  [L=309]
Description: mitochondrial DNA replication protein (Yhm2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
      1e-27   95.9   2.2    4.9e-12   45.6   0.0    3.2  3  Mito_carr  Mitochondrial carrier protein


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.4   0.1   2.3e-09   4.2e-05       7      84 ..      17      88 ..      12     100 .. 0.78
   2 !   25.2   0.2   6.3e-10   1.1e-05      12      91 ..     113     194 ..     103     200 .. 0.67
   3 !   45.6   0.0   2.7e-16   4.9e-12       3      93 ..     208     297 ..     206     300 .. 0.90

  Alignments for each domain:
  == domain 1  score: 23.4 bits;  conditional E-value: 2.3e-09
                HHHHHHHHHHHH.HHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHH CS
   Mito_carr  7 kellaGglagav.atlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfv 84
                ++ll G+   ++  t++ +Pl+v+Kt + ++++ s       +++++++i+   G++g y+Gl+p     a+++++ ++
  EEA22925.1 17 SNLLLGAGLNMFeVTTLGQPLEVIKTTMAANRTDS-------FASAMSRIWGRGGILGYYQGLIPWAWIEASTKGAVLL 88
                455556555565257899***********999996.......8899******************987777777665554 PP

  == domain 2  score: 25.2 bits;  conditional E-value: 6.3e-10
                 HHHHHHHHHHHHHHH.HHHHHHHHHCCCSSTTTSCSS..HHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr  12 GglagavatlvttPl.dvvKtrlqtqkksskksksaa..ildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkr 91 
                 G+ +g++++ +t  +   +Kt   t  k+s++ + ++  +++++  iy++eG+rg  +G+++  +r++ +++ +f+l     +
  EEA22925.1 113 GMSGGVAQAYATVGFcTCMKTVEITRHKMSAT-GVQPpsTWQTFMDIYRKEGIRGINKGVNAVAIRQTTNWGSRFGLSRLAEN 194
                 33334444444444413445544444444433.333346************************************98766555 PP

  == domain 3  score: 45.6 bits;  conditional E-value: 2.7e-16
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   3 lsvlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrll 93 
                 l++ ++++a+g++g ++    +P++v+++ +q++++  +  k+  + +++k iy+++G++glyrG+ p++   + +++++++l +  k+ +
  EEA22925.1 208 LNAGEKIIASGVGGGLS-AWNQPIEVIRVEMQSKADDPNRPKNLTVGKTFKYIYETNGIKGLYRGVAPRIGLGMWQTVCMVALGDLAKEAV 297
                 56678889999999885.578****************99999888*************************************999999876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       367  (0.0204696); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.43
# Mc/sec: 2149.76
//
Query:       EEA22926.1  [L=472]
Description: citrate synthase (Cit1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
   3.1e-102  342.4   0.0   3.9e-102  342.0   0.0    1.1  1  Citrate_synt  Citrate synthase, C-terminal domain
  ------ inclusion threshold ------
      0.086   12.5   0.0       0.16   11.7   0.0    1.3  1  Eclosion      Eclosion hormone


Domain annotation for each model (and alignments):
>> Citrate_synt  Citrate synthase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  342.0   0.0  4.3e-106  3.9e-102       1     361 []      78     457 ..      78     457 .. 0.92

  Alignments for each domain:
  == domain 1  score: 342.0 bits;  conditional E-value: 4.3e-106
                   GGTTEEEEEESSEEEETTTTEEEETTEEHHHHH.........HHHS-HHHHHHHHHHSS---HHHHHHHHHHHHCTTS--HHHHHHHHCSSTTS-HH CS
  Citrate_synt   1 glrgvaaleteisevdgekgelrYRGydieeLa.........eekssfeevaylLltgelPtkeelkefkeelaearklpekvlealealpkdahpm 88 
                   g rg+++l +e s +d e+  +r+RG++i+e +         +e+   e  ++lLltge+P++++++++++e+a+++ +p+ v e +++ p+d+hpm
    EEA22926.1  78 GARGIKSLVWEGSVLDSEE-GIRFRGRTIPE-CqeilpkapgGEEPLPEGLFWLLLTGEVPSEQQVRDLSAEWAARSDVPKFVEELIDRCPNDLHPM 172
                   678999*********9444.4**********.77*******7546667779999*****************************99999********* PP

                   HHHHHHHHHHHHHSTT......CTCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS.--.---TTSSHHHHHHHHHHSS---HHHHHHHHHHHHH CS
  Citrate_synt  89 avlraavsalsaddee......seakeeseeaalrdalkliAklptiaaaiyrarlgrepl.epddklsyaenflymlrgkkpdeeeaklldlalvl 178
                   a+++ av+al+++++       + +k+e+++++++d+++liAklptiaa+iyr+ +++ ++   +++++ya n+++ l     ++++++l++l+l++
    EEA22926.1 173 AQFSLAVTALEHESSFakayakGLNKKEYWQYTFEDSMDLIAKLPTIAARIYRNVFKDGKVaPIQKDKDYAFNLANQLGF-GDNKDFVELMRLYLTI 268
                   *********8877766666665777777*****************************9888445588***********54.6799************ PP

                   HS--SS.SHHHHHHHHHHTTT--HHHHHHHHHHHHTSTTTTTHHHHHHHHHHHHSSGG........GHHHHHHHHHHTTTS--TTBC-SSSSS--HH CS
  Citrate_synt 179 haDHel.naSTfaarvvaStladlysaiaagigalkGplhgganeavlkmleeigsaev.......eveeylekvlakekerlpGfGHrvykksDpR 267
                   h DHe+ n+S++++++v+S+l+ +y ++aag+++l+Gplhg an++vl +l+++ ++++        +++yl+++l+++ +++pG+GH+v++k+DpR
    EEA22926.1 269 HSDHEGgNVSAHTTHLVGSALSSPYLSLAAGLNGLAGPLHGLANQEVLVWLQKM-KKAIgndlsdeAIKDYLWSTLNAG-QVVPGYGHAVLRKTDPR 363
                   ******************************************************.55578999**9***********86.***************** PP

                   HHHHHHHHHHHHTCHTHHHHHHHHHHHHHHHHHHHHCHH.GCT-EB-THHHHHHHHHHTT--GGG.HHHHHHHHHHHHHHHHHHHHH.HT------E CS
  Citrate_synt 268 akilkelaeelaeekgkdpllklaeeleevapevlkeke.eknlypNvDfysgvlyralgipeel.ftvlfaisRvaGwlAhileql.adnkiiRPr 361
                   ++ ++e+a ++     +dp++kl+++++++ap vl+e+  +kn+ypNvD++sgvl++++g++e   +tvlf++sR++G+l +++  +     i+RP+
    EEA22926.1 364 YVSQREFALRHLP---DDPMFKLVSQVYKIAPGVLTEHGkTKNPYPNVDAHSGVLLQYYGLTEANyYTVLFGVSRALGVLPQLIIDRaLGAPIERPK 457
                   ********88775...9*******************9999*********************99745******************988555779*996 PP

>> Eclosion  Eclosion hormone
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   1.8e-05      0.16      34      51 ..      94     111 ..      85     116 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 1.8e-05
    Eclosion  34 aeaClkfkGkliPdCedi 51 
                 +e  ++f+G++iP+C++i
  EEA22926.1  94 SEEGIRFRGRTIPECQEI 111
                 56789**********997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (472 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       363  (0.0202465); expected 358.6 (0.02)
Passed bias filter:                      359  (0.0200234); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.52u 0.23s 00:00:00.75 Elapsed: 00:00:00.40
# Mc/sec: 3497.50
//
Query:       EEA22927.1  [L=706]
Description: RNA binding protein Nrd1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.1e-09   38.9   0.0    2.1e-09   38.0   0.0    1.5  1  CTD_bind  RNA polymerase II-binding domain.
    1.2e-05   25.0   0.0    2.3e-05   24.1   0.0    1.5  1  RRM_1     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom


Domain annotation for each model (and alignments):
>> CTD_bind  RNA polymerase II-binding domain.
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.0   0.0   2.4e-13   2.1e-09       1      63 []      61     138 ..      61     138 .. 0.84

  Alignments for each domain:
  == domain 1  score: 38.0 bits;  conditional E-value: 2.4e-13
    CTD_bind   1 kLnllYLaNdvlqns...krkq............kdefapaFapvlpeafadaykkapekikkklkrllniWeernvf 63 
                 kL +lY++++v++++   +rk                 +++  + lp ++ad++++ape++k+k+++l++iWe  ++f
  EEA22927.1  61 KLGVLYVVDSVTRQWveaARKAgqplgsaapdgtFAAGVNRVTELLPVLMADIINNAPEDQKEKIRKLVDIWERGQTF 138
                 89***********998875665789998887544444488888888888************************88876 PP

>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.0   2.5e-09   2.3e-05      10      69 ..     487     541 ..     480     542 .. 0.89

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 2.5e-09
                 SSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1  10 vteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkklggrel 69 
                 + e+ L++lF+++G ++++ +  d     k++af+++ +++dA +A e +  +k g+ +l
  EEA22927.1 487 APESHLRALFNQYGVVQTCIVNVD-----KRHAFIKMINRRDAMNAREGMETYKSGDMQL 541
                 56899******************9.....*********************9999888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (706 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       406  (0.0226449); expected 358.6 (0.02)
Passed bias filter:                      259  (0.0144459); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.46
# Mc/sec: 4590.72
//
Query:       EEA22928.1  [L=616]
Description: RNA binding protein Nrd1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.4e-10   39.2   0.0    1.8e-09   38.3   0.0    1.5  1  CTD_bind  RNA polymerase II-binding domain.
      1e-05   25.3   0.0    1.9e-05   24.4   0.0    1.5  1  RRM_1     RNA recognition motif. (a.k.a. RRM, RBD, or RNP dom


Domain annotation for each model (and alignments):
>> CTD_bind  RNA polymerase II-binding domain.
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.3   0.0     2e-13   1.8e-09       1      63 []      61     138 ..      61     138 .. 0.84

  Alignments for each domain:
  == domain 1  score: 38.3 bits;  conditional E-value: 2e-13
    CTD_bind   1 kLnllYLaNdvlqns...krkq............kdefapaFapvlpeafadaykkapekikkklkrllniWeernvf 63 
                 kL +lY++++v++++   +rk                 +++  + lp ++ad++++ape++k+k+++l++iWe  ++f
  EEA22928.1  61 KLGVLYVVDSVTRQWveaARKAgqplgsaapdgtFAAGVNRVTELLPVLMADIINNAPEDQKEKIRKLVDIWERGQTF 138
                 89***********998875665789998887544444488888888888************************88876 PP

>> RRM_1  RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.4   0.0   2.1e-09   1.9e-05      10      69 ..     487     541 ..     480     542 .. 0.89

  Alignments for each domain:
  == domain 1  score: 24.4 bits;  conditional E-value: 2.1e-09
                 SSHHHHHHHHHTTSCEEEEEEEEETTTSEEEEEEEEESSHHHHHHHHHHHTTEEETTEEE CS
       RRM_1  10 vteeeLkelFskfGpiksiklvrdetgkskgfafVeFeskedAekAlealngkklggrel 69 
                 + e+ L++lF+++G ++++ +  d     k++af+++ +++dA +A e +  +k g+ +l
  EEA22928.1 487 APESHLRALFNQYGVVQTCIVNVD-----KRHAFIKMINRRDAMNAREGMETYKSGDMQL 541
                 56899******************9.....*********************9999888776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (616 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       479  (0.0267165); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.34s 00:00:00.94 Elapsed: 00:00:00.49
# Mc/sec: 3798.51
//
Query:       EEA22929.1  [L=120]
Description: hypothetical protein PMAA_095330 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.058   13.2   0.0      0.065   13.0   0.0    1.2  1  ALO       D-arabinono-1,4-lactone oxidase


Domain annotation for each model (and alignments):
>> ALO  D-arabinono-1,4-lactone oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   3.6e-06     0.065     235     254 ..      87     106 ..      48     110 .. 0.93

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 3.6e-06
         ALO 235 dlkkflkvRkklDPegvFln 254
                  lkkfl++R+k DPe +F++
  EEA22929.1  87 ALKKFLAIRQKWDPEDMFVG 106
                 699***************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (120 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       354  (0.0197445); expected 358.6 (0.02)
Passed bias filter:                      311  (0.0173462); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.39u 0.26s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 853.28
//
Query:       EEA22930.1  [L=442]
Description: homocysteine synthase CysD [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   3.4e-152  506.4   0.0   3.9e-152  506.2   0.0    1.0  1  Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
    2.4e-10   40.3   1.4    2.4e-10   40.3   1.4    1.6  2  DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family
    5.8e-09   35.6   0.2    1.9e-08   33.9   0.1    1.7  2  Aminotran_1_2    Aminotransferase class I and II
    9.5e-07   28.1   0.4    1.7e-06   27.3   0.4    1.4  1  Aminotran_5      Aminotransferase class-V
    1.5e-06   27.7   0.0    2.6e-06   27.0   0.0    1.2  1  Beta_elim_lyase  Beta-eliminating lyase
     0.0024   16.5   0.1     0.0031   16.1   0.1    1.2  1  Met_gamma_lyase  Methionine gamma-lyase
     0.0026   16.7   0.0     0.0039   16.1   0.0    1.2  1  GDC-P            Glycine cleavage system P-protein
     0.0092   16.2   0.1      0.061   13.6   0.0    2.1  2  Asparaginase_C   Glutaminase/Asparaginase C-terminal domain
  ------ inclusion threshold ------
      0.061   12.0   0.0      0.088   11.5   0.0    1.2  1  SepSecS          O-phosphoseryl-tRNA(Sec) selenium transferas
      0.071   12.3   0.0       0.12   11.5   0.0    1.3  1  ABC_sub_bind     ABC transporter substrate binding protein


Domain annotation for each model (and alignments):
>> Cys_Met_Meta_PP  Cys/Met metabolism PLP-dependent enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  506.2   0.0  2.2e-155  3.9e-152       1     381 [.       7     424 ..       7     425 .. 0.99

  Alignments for each domain:
  == domain 1  score: 506.2 bits;  conditional E-value: 2.2e-155
                      HHHHHHTTTTCHTTTTBSS--B---SBBBESSHHHH...CTTCSSS-SBTTT--HHHHHHHHHHHHHHT-SEEEEESSHHHHHHHHHHTTS-TT CS
  Cys_Met_Meta_PP   1 eTllvhagqekdeqtgavavpiyltstykfkdvdea...fageekgyeYsRsgnptrsvleeriaaLeggeaalavssGmaAiaaailallkaG 91 
                      eTl++hagqe+d++t+++avpiy+t++y+f+d++++   f+ +e g++YsR++npt++v+e+riaaLegg aa+a ssG+aA+++ai al++aG
       EEA22930.1   7 ETLQLHAGQEPDPATNSRAVPIYATTSYVFNDSAHGarlFGLKEFGNIYSRIMNPTVDVFEKRIAALEGGVAAVAASSGQAAQFMAISALAHAG 100
                      69*********************************99********************************************************* PP

                      EEEEEESTSSHHHHHHHHHTHHHTTCEEEEESTTSHHHHHHHCCTTEEEEEEESS-TTTT----HHHHHHHHHHTT-EEEEEGTTTHT.TTS-G CS
  Cys_Met_Meta_PP  92 deivvsddlYggtqrllkkvlkklgievkfvdtsdleelekaikentklvylEtptnpllkvvDiekiaklakkagvlvvvDntfasp.llqrp 184
                      d+iv++++lYggt+++lk +l++lgi++kfv+ +++e++++ai+++tk+vy+Et++np ++v+D+e+iak+a+++gv++vvDntf ++ ++ rp
       EEA22930.1 101 DNIVATSNLYGGTYNQLKVFLPRLGIQTKFVNGDNAEDIAAAIDDHTKAVYVETIGNPRYNVPDFEAIAKVAHEKGVPLVVDNTFGAGgYFARP 194
                      **************************************************************************************998***** PP

                      GGGT-SEEEEETTTTTTCSSS--EEEEEESSCHHHHHHHHHHH................................HHHT-B--HHHHHHHHHHH CS
  Cys_Met_Meta_PP 185 lklgaDivvhSaTKylgGhsdvvaGvivvkgkeelkkelkflq................................nalGavlspfdawlllrGl 246
                      +++gaDivvhSaTK++gGh+++++Gv+v++gk++++k++++++                                ++lG++l+pf+a +ll Gl
       EEA22930.1 195 IDHGADIVVHSATKWIGGHGTTIGGVVVDSGKFDWGKHAARFPqfvepaegyhglkfwetfgpiafairvrveilRDLGSALNPFAAQQLLLGL 288
                      **************************************999889************************************************** PP

                      TTHHHHHHHHHHHHHHHHHHHHTSTTEEEEE-TTSTTSTTHHHHHHHS.SSG-SEEEEEESSHHHHHHHHHHC-SSSEECSS-SSSS-EEEETT CS
  Cys_Met_Meta_PP 247 kTLslRlerhqenAlkvAefLekhpkvekvyYpglpshpqhelakkql.kgaggvlsFelkseeekakkfvdnlklfslaeslGgveslielpa 339
                      +TLslR erh++nAl++A++Lek+++v++v+Ypgl+sh +he+akk+l +g+ggvlsF +k+++++ +++vd +kl+s+++++G+ ++l+++p+
       EEA22930.1 289 ETLSLRAERHASNALTLAKWLEKNENVSWVSYPGLESHASHETAKKYLpRGFGGVLSFGVKGGAAAGSQVVDGFKLISNLANVGDSKTLAIHPW 382
                      **********************************************98578899**************************************** PP

                      TTTTTTSCHHHHHHTTS-TTEEEEE--SS-HHHHHHHHHHHH CS
  Cys_Met_Meta_PP 340 smthasipkeereaagvtddliRlsvGiEdvdDliaDlkqal 381
                      s+th+++++eer+a+gvt+d iR+svG E++dD+iaD++q++
       EEA22930.1 383 STTHEQLSEEERIASGVTEDAIRISVGTEHIDDIIADFEQSF 424
                      ****************************************99 PP

>> DegT_DnrJ_EryC1  DegT/DnrJ/EryC1/StrS aminotransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.3   1.4   1.3e-13   2.4e-10      20     150 ..      58     188 ..      49     222 .. 0.85
   2 ?   -2.8   0.0       1.7   3.1e+03     222     277 ..     276     330 ..     272     334 .. 0.78

  Alignments for each domain:
  == domain 1  score: 40.3 bits;  conditional E-value: 1.3e-13
                      SSSHHHHHHHHHHHHHHT-SEEEEESSHHHHHHHHHHHTTTTTT-EEEEESSS-THHHHHHH....HTT-EEEEE-B-TTTSSB-GGGCGGG-- CS
  DegT_DnrJ_EryC1  20 tsgpeveeFEkafaaylgvkhaiavssGtaAlhlaLralgvgpgdeVIvpsltFvatanavl....elgakpvfvDvdpdtynidpaaieaait 109
                      +++p+v+ FEk++aa  g   a+a ssG aA  +a++al    gd ++ +s+ + +t n       +lg ++ fv+ d      ++++i+aai 
       EEA22930.1  58 IMNPTVDVFEKRIAALEGGVAAVAASSGQAAQFMAISALAHA-GDNIVATSNLYGGTYNQLKvflpRLGIQTKFVNGD------NAEDIAAAID 144
                      5699**********************************9877.9**************9864333489*******999......789******* PP

                      TTEEEEEEB-GGGB--....-HHHHHHHHHHCT-EEEEE-TT-TT CS
  DegT_DnrJ_EryC1 110 ertkaIlpVhlyGqva....dmdalkaiaakhglkvieDaAhAlG 150
                        tka+  V++ G++     d++a+ ++a+++g++++ D   + G
       EEA22930.1 145 DHTKAV-YVETIGNPRynvpDFEAIAKVAHEKGVPLVVDNTFGAG 188
                      *****8.68999986444569*****************9776665 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1.7
                      -BHHHHHHHHHHHCTHHHHHHHHHHHHHHHHHHHHTCCCCEESCGGTTSSSEEESC CS
  DegT_DnrJ_EryC1 222 lteiqAAiglaqLerldelvarRreiaelykeeLaelegtaelttpketkkhawhl 277
                      l+ ++A  +l  Le l+   +r   +a ++ + L++ e+++ +  p  ++ ha h 
       EEA22930.1 276 LNPFAAQQLLLGLETLSLRAERHASNALTLAKWLEKNENVSWVSYPGLES-HASHE 330
                      55666777777888999999999999999999999999888888777777.77776 PP

>> Aminotran_1_2  Aminotransferase class I and II
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.9   0.1     1e-11   1.9e-08      46     237 ..      63     224 ..      31     246 .. 0.80
   2 ?   -1.5   0.0       0.6   1.1e+03     222     281 ..     345     406 ..     345     423 .. 0.76

  Alignments for each domain:
  == domain 1  score: 33.9 bits;  conditional E-value: 1e-11
                    HHHHHHHHHHHHCTCTTCHTTGGEGEEEESHHHHHHHHHHHHHHHTTT-EEEEEES....S-THHHHHHHHTTSEEEEEEBEETTTTEE-HHHHHH CS
  Aminotran_1_2  46 lpeleealakflgrseklklkreaavvvgsGagaliealifllklnpgdeilvpdp....tyasyknilrlsggevvryplyseedfhldlealee 137
                     + +e+++a + g          aav  +sG +a++ ++i +l + +gd+i++ +     ty + k  l   g++   ++       + ++e++ +
     EEA22930.1  63 VDVFEKRIAALEG--------GVAAVAASSG-QAAQFMAISAL-AHAGDNIVATSNlyggTYNQLKVFLPRLGIQTKFVN-------GDNAEDIAA 141
                    5678889999988........6645555555.67777777777.78******9987222245555666667899999999.......889****** PP

                    HHTTHHCTTETEEEEEEESS-TTT--B--HHHHHHHHHHHHHTTEEEEEEETTTTCBSSSSHTHHHHGGSTTSTTEEEEEESSSTTSSGGG-EEEE CS
  Aminotran_1_2 138 alkeapegnkktkvilvesphNPtGtvatleeleklldlakkynlllfvDeaYagfvfgsldavatranveeepnllivgslsKafGlaGeRvGyi 233
                    a+++       tk ++ve++ NP   v++ e + k+   a+++++ l+vD +++++ +           ++++ + ++v s  K  G  G  +G +
     EEA22930.1 142 AIDD------HTKAVYVETIGNPRYNVPDFEAIAKV---AHEKGVPLVVDNTFGAGGYF-------ARPIDHGAD-IVVHSATKWIGGHGTTIGGV 220
                    ****......99***********9888888888888...****************9997.......445566655.******************** PP

                    EEEH CS
  Aminotran_1_2 234 lgna 237
                    ++++
     EEA22930.1 221 VVDS 224
                    9987 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 0.6
                    TTSSGGG-EEEEEEEH.....HHHHHHHHHHHHHTSSHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
  Aminotran_1_2 222 afGlaGeRvGyilgna.....avvsqlrklsrpflsssllqaavaaalsdallkqseleemrqrl 281
                    +fG+ G   G+++g++     +++s l+++  + +   +    + + ls +++++s ++e + r+
     EEA22930.1 345 SFGVKG---GAAAGSQvvdgfKLISNLANVGDSKTLAIHPWSTTHEQLSEEERIASGVTEDAIRI 406
                    689999...99999988888888888888877777777777777777777777777777777776 PP

>> Aminotran_5  Aminotransferase class-V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.4   9.3e-10   1.7e-06      85     210 ..      97     217 ..      26     222 .. 0.80

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 9.3e-10
                  -TTTSEEEEETTSHGGGTHHHHHHHHHHTEEEEEEEBETTSCBEGGGHHHH--TTEEEEEEESBETTTTEB--HHHHHHHHHHTT-EEEEE-TTTTTT CS
  Aminotran_5  85 lkpgdeivvteaehhanlvpwqelakrtgakvkvipldeegeldldelekllnektklvaithvsnvtGtiqpveeigklakkkgalvlvDaaqavgh 182
                   ++gd+iv t++ + ++ +  +    r g++ k+++ d+      +++++++++ tk+v++  + n   ++ ++e+i+k+a++kg+ ++vD + ++g 
   EEA22930.1  97 AHAGDNIVATSNLYGGTYNQLKVFLPRLGIQTKFVNGDN-----AEDIAAAIDDHTKAVYVETIGNPRYNVPDFEAIAKVAHEKGVPLVVDNTFGAGG 189
                  456666666666666666555555555555555554432.....467889********************************************9999 PP

                  S---HHHHTESEEEEETTTTTSSTT-EE CS
  Aminotran_5 183 ipidvkklgvDflafsghKllgPtGiGv 210
                  +     + g+D+++ s+ K +g  G+++
   EEA22930.1 190 YFARPIDHGADIVVHSATKWIGGHGTTI 217
                  9999999******************986 PP

>> Beta_elim_lyase  Beta-eliminating lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.0   0.0   1.4e-09   2.6e-06      31     271 ..      60     310 ..      55     319 .. 0.84

  Alignments for each domain:
  == domain 1  score: 27.0 bits;  conditional E-value: 1.4e-09
                      -HHHHHHHHHHHHHTT-SEEEEES-HHHHHHHHHHHH--TTEEEEEETT-HHHHSSTTHHHHC...C--EEEEE-EBTTTBE-HHHHHHHS--S CS
  Beta_elim_lyase  31 dktvnrLedavaelfgkeaalfvpqGtaAnsillkillqrgeevivtepahihfdetgaiael...agvklrdlknkeaGkmdlekleaaikev 121
                      ++tv ++e+++a+l g  aa+ + +G aA  +++++l++ g+++++t  ++ +  +  +++++    g++ + +++++     +e+++aai++ 
       EEA22930.1  60 NPTVDVFEKRIAALEGGVAAVAASSGQAAQFMAISALAHAGDNIVAT--SNLYGGTYNQLKVFlprLGIQTKFVNGDN-----AEDIAAAIDD- 145
                      78999*************************************99876..66666666555555334677777777777.....9********9. PP

                      -TTS-EEEEEEEESSBTTTTTB---HHHHHHHHHHHHHCT-EEEEEETTHHHHHHHHTS-CHHHHTTSSEEEEESSS...TT--SS-EEEEE-H CS
  Beta_elim_lyase 122 gaheekiklisltvTnntagGqvvsleelrevaaiakkygiplhlDgARfanaakslgeivkemfsyvDsvtmslkK...dllanvGgvlafrd 212
                            +k++++++  n      + +   +++a++a+++g+pl++D     n   + g  ++ +  ++D+v+ s++K   + ++ +Ggv++ + 
       EEA22930.1 146 -----HTKAVYVETIGN----PRYNVPDFEAIAKVAHEKGVPLVVD-----NTFGAGGYFARPIDHGADIVVHSATKwigGHGTTIGGVVVDSG 225
                      .....477999987777....58***********************.....567788999999**************77667899******999 PP

                      H..................................HHHHHHHHHHHHT---SSTHHHHH..HHHHHHHHSSTTHHHHHHHHHHHHHHHH CS
  Beta_elim_lyase 213 del..............................edylaerveqrkylggglrqagvlaaleagiraleeglaslerdhktaeqlaekle 271
                      +                                   ++ rve  + lg+ l+   + a+    +  le  + ++er+  +a +la+ le
       EEA22930.1 226 KFDwgkhaarfpqfvepaegyhglkfwetfgpiAFAIRVRVEILRDLGSALN--PFAAQ--QLLLGLETLSLRAERHASNALTLAKWLE 310
                      9558899999999999999999999999988875567888888888888888..56666..8888888888888888888888877666 PP

>> Met_gamma_lyase  Methionine gamma-lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.1   1.7e-06    0.0031     145     242 ..     136     229 ..      37     242 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 1.7e-06
  Met_gamma_lyase 145 ieavkeaikektkliliqrskGyserkslsieeieeiiklvkeinedvivfvdncyGefveekePtevGadliaGsliknpGGgiaktGGyia. 237
                       e +++ai ++tk + +    G    + +++ + e i k+ +  ++ v + vdn +G       P++ Gad++  s  k +GG  +++GG ++ 
       EEA22930.1 136 AEDIAAAIDDHTKAVYVET-IG---NPRYNVPDFEAIAKVAH--EKGVPLVVDNTFGAGGYFARPIDHGADIVVHSATKWIGGHGTTIGGVVVd 223
                      5566677777777776653.33...45567777766666554..45667789***************************************974 PP

  Met_gamma_lyase 238 .Gkeel 242
                       Gk ++
       EEA22930.1 224 sGKFDW 229
                      466666 PP

>> GDC-P  Glycine cleavage system P-protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.1   0.0   2.1e-06    0.0039     142     259 ..      88     208 ..      72     219 .. 0.82

  Alignments for each domain:
  == domain 1  score: 16.1 bits;  conditional E-value: 2.1e-06
                 HHHHHHHH-SSS--EEEEETTS-HHHHHHHHHHHGGGT-EE..EEE-GGG--S-...S-EEEEEEEES.-TTSB----HHHHHHHHHTT-EEEEEE-TT CS
       GDC-P 142 Avllaaraskkkakkvvvdkkvhpqtlevlktrakglgiei..vevdlteekvtdkekevagvlvqyp.nteGriedlkelvekakkkkslvvvaadll 237
                 A  +a  a  +  +++v  ++++  t + lk     lgi++  v  d +e+ ++   +++ +v v    n   ++ d++++++ a++k + +vv     
  EEA22930.1  88 AQFMAISALAHAGDNIVATSNLYGGTYNQLKVFLPRLGIQTkfVNGDNAEDIAAAIDDHTKAVYVETIgNPRYNVPDFEAIAKVAHEKGVPLVVDNTFG 186
                 444556666677889******************9999987621556667777777899999*999865266889************************* PP

                 GGGTB--HHHHT-SEEEEE-TT CS
       GDC-P 238 aLtllkpPgelgaDivvGsaqr 259
                 a + ++ P + gaDivv sa +
  EEA22930.1 187 AGGYFARPIDHGADIVVHSATK 208
                 *****************99865 PP

>> Asparaginase_C  Glutaminase/Asparaginase C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.0      0.86   1.5e+03      39      69 ..      84     117 ..      73     127 .. 0.74
   2 !   13.6   0.0   3.4e-05     0.061       6      57 ..     129     181 ..     126     193 .. 0.90

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.86
                     H...HHHHHHHHHHTTT-EEEEEESSSBS----- CS
  Asparaginase_C  39 s...allealkeakargivvvatsqcpsgsvsns 69 
                     s   a   a++ +  +g  +vats  + g+ ++ 
      EEA22930.1  84 SgqaAQFMAISALAHAGDNIVATSNLYGGTYNQL 117
                     2444677889999999999999999999988876 PP

  == domain 2  score: 13.6 bits;  conditional E-value: 3.4e-05
                     E--TT--HHHHHHHHHTT--EEEEEEBTTTB--H.HHHHHHHHHHTTT-EEEE CS
  Asparaginase_C   6 klhpgmdtkvlkallkkgakGvvlegtGvGnlps.allealkeakargivvva 57 
                     k++ g +++ + a+++ + k+v +e+ G+   +  ++   +k+a ++g+++v+
      EEA22930.1 129 KFVNGDNAEDIAAAIDDHTKAVYVETIGNPRYNVpDFEAIAKVAHEKGVPLVV 181
                     6778889999***********************77****************98 PP

>> SepSecS  O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0   4.9e-05     0.088     145     196 ..     137     187 ..     127     222 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 4.9e-05
                 HHHHHCCTCCCEEEEEECSSTTT.TB----HHHHHHHHHCCT--EEEEGCCCC CS
     SepSecS 145 eeiiekkreevilavlstlsffa.prspDdvkeiakiCaeydvPhlvNgAYai 196
                 e+i   + +  + av   + +++  ++pD  ++iak+ +e +vP++v + ++ 
  EEA22930.1 137 EDIAAAIDDH-TKAVYVETIGNPrYNVPD-FEAIAKVAHEKGVPLVVDNTFGA 187
                 5555554444.444444444444158999.*******************9986 PP

>> ABC_sub_bind  ABC transporter substrate binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.0     7e-05      0.12     151     217 ..     116     182 ..     113     189 .. 0.92

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 7e-05
                   HHHHHHHHTT-EEEEEE-SSGGGHHHHHHHHHTT-SEEEE-S-HHHHHTHHHHHHHHHHTT--EEES CS
  ABC_sub_bind 151 elkklakkaglkvveaavknvndvesavsslaekvdaiyiltdnliasafeavvkaanqakiPvias 217
                   +lk  +++ g++   +  +n +d+++a+   ++ v++  i ++ + ++ fea+ k+a+++++P++  
    EEA22930.1 116 QLKVFLPRLGIQTKFVNGDNAEDIAAAIDDHTKAVYVETIGNPRYNVPDFEAIAKVAHEKGVPLVVD 182
                   5778888899999999999********************************************9975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (442 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       404  (0.0225333); expected 358.6 (0.02)
Passed bias filter:                      347  (0.0193541); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.58u 0.31s 00:00:00.88 Elapsed: 00:00:00.48
# Mc/sec: 2755.02
//
Query:       EEA22931.1  [L=156]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-19   70.0  17.5    2.6e-19   69.7  17.5    1.1  1  MARVEL    Membrane-associating domain


Domain annotation for each model (and alignments):
>> MARVEL  Membrane-associating domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.7  17.5   1.5e-23   2.6e-19       9     144 .]      14     137 ..      10     137 .. 0.91

  Alignments for each domain:
  == domain 1  score: 69.7 bits;  conditional E-value: 1.5e-23
      MARVEL   9 lrilqlvfaiiilgliaslia.kldqllgspssalnfavfvavfsflyalfllvlylfknsaftsilwplidlivdalaallwlvafialaaglrdisc 106
                 +ri+q vfaiiilgl+a++i+ +       +s ++nf +f +++++l+al +l l  +   +f + ++ +++l+++ +++++w+++fial a l +   
  EEA22931.1  14 VRIVQAVFAIIILGLTAYAINvE-LEWSWYSSNTINFDLFNSIWTLLVALPYLSLVPI---FFANLSHHYAVLVIEIVTMIFWFAGFIALGALLPP--- 105
                 8*******************742.23344457899********************998...9**********************************... PP

      MARVEL 107 afesnqysasltvrcgqaqaavafgflavllfaasavl 144
                         a+++  c+++qaa++fg++ +llfa+++ +
  EEA22931.1 106 ------PRACHGNFCSSLQAATVFGAFEWLLFAITTAF 137
                 ......56677999********************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (156 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       734  (0.0409393); expected 358.6 (0.02)
Passed bias filter:                      265  (0.0147805); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.37u 0.21s 00:00:00.57 Elapsed: 00:00:00.37
# Mc/sec: 1272.45
//
Query:       EEA22932.1  [L=556]
Description: arginine transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
   3.5e-133  444.7  50.5   4.1e-133  444.5  50.5    1.0  1  AA_permease    Amino acid permease
    7.8e-32  110.6  56.5    9.8e-32  110.3  56.5    1.1  1  AA_permease_2  Amino acid permease


Domain annotation for each model (and alignments):
>> AA_permease  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  444.5  50.5  4.6e-137  4.1e-133       1     474 [.      63     523 ..      63     527 .. 0.97

  Alignments for each domain:
  == domain 1  score: 444.5 bits;  conditional E-value: 4.6e-137
  AA_permease   1 hvlvialggviGtglfvglgvvlsqaGplgallayllagvviflvmlslgeiatngpksggfytyasrflgpelGfviGlnylfswitvlaleltaas 98 
                  h+++ia+gg iGtglf+g+g ++++aGp+gal+ayl++g +++ vm slge+at++p  g+f+ ya+rf++p+lGf++G++y+fsw++++alelta +
   EEA22932.1  63 HLQMIAIGGTIGTGLFIGSGTAIANAGPAGALIAYLFVGSIVYSVMTSLGEMATYIPIPGAFTSYAARFVDPSLGFAMGWIYWFSWAITFALELTATG 160
                  99************************************************************************************************ PP

  AA_permease  99 iliqfwelvtdlpkawvtgavflvvlliinlvgvkvygeaefilalikiiaiiafiivgiillaggkpnkgagfrflgdngsifknnlppgfakeeeg 196
                   +iq+w   ++++ + +++avf+v +++ nl+ v +yge ef+l+ +kii+i++f+i+ i++ ag+++ +  gf+ +g++g+ f+ +l ++ +   + 
   EEA22932.1 161 LIIQYW--AQSVS-IGIFIAVFWVCITAANLLPVGFYGELEFWLSTVKIITIVGFMIFAICIDAGAGNRPYLGFHTWGNPGA-FAPYLLES-T-GPTA 252
                  ******..99999.**********************************************999999988877**********.66666666.2.4445 PP

  AA_permease 197 afknfisvfvivvfaftGielvaiiagEvkdPeksiPkailqvviritifYvlsllligllvprndlgllndsasa.aspfvifikesgvsvlaplin 293
                   f +f +v++++ f+++G+elv+i+ gE+++P+k++P ai+++++ri++f+vl +++igllvp++++ l ++  +a aspfvi+   +gv+vl+ +in
   EEA22932.1 253 KFVGFWAVLIQAGFSYQGTELVGIAVGECENPRKTMPSAIRKTFYRILLFFVLTIFFIGLLVPYTNDRLASGGSDAsASPFVIAADLAGVKVLPGIIN 350
                  6**********************************************************************9999999******************** PP

  AA_permease 294 aviltaalssansslysasRvlyslakdglaPkvlkkvskrgvPlraillsmiisllalllaslnlaapivfnfllaisaliglivwlliilsylrfR 391
                   v+lt +ls+ans +ys+sR+l  la++g aP++lk  s +gvP+ ++++++ i+lla+l+ s n +  +vfn++++is+++g+i w + + +++ f+
   EEA22932.1 351 GVLLTVVLSAANSNVYSGSRILIGLAQEGFAPRFLKTTSAQGVPYYGVAVTSTIGLLAFLNLSNNGS--TVFNWFVNISGVAGFISWSVLNGCHIAFM 446
                  ***********************************************************99999999..***************************** PP

  AA_permease 392 kalkyqgrsieelgfkaallplgvilvlaaliiillilalyayltvkkgpkdwgaasfaaaylivllfliilvgvklhvknkr 474
                  +al ++++s ++l++ka  +p++++++l+++++i+l+++++a+++      +++++sf+ ay++++lf+++++g+k+ +++k+
   EEA22932.1 447 RALAARNISRDLLPYKAMWQPFFAWYGLFFNVLIILTQGFTAFIP------TFNVSSFFVAYISLILFVVLYLGHKIVFRTKF 523
                  *********************************************......9****************************987 PP

>> AA_permease_2  Amino acid permease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.3  56.5   1.1e-35   9.8e-32       7     422 ..      65     508 ..      59     512 .. 0.75

  Alignments for each domain:
  == domain 1  score: 110.3 bits;  conditional E-value: 1.1e-35
  AA_permease_2   7 falvigsvigsgifvkn..laasggpa..lilwvwiavligslavllvyaElssalprsgGiyvytkaafgkkvaflsawfnwfayvpvlasilsv 98 
                     +++ig +ig+g f+ +  ++a++gpa  li ++++++++  ++v+  + E+++ +p  g   +y++++  + ++f ++w++wf++++++a+ l++
     EEA22932.1  65 QMIAIGGTIGTGLFIGSgtAIANAGPAgaLIAYLFVGSIV--YSVMTSLGEMATYIPIPGAFTSYAARFVDPSLGFAMGWIYWFSWAITFALELTA 158
                    5799************999999999984455555666665..579999*******************************************99999 PP

  AA_permease_2  99 aasyllnalgpdlqgntwltyliaiaililva.linirgikesakiqnilgilkillpliiliilglitvdgggfssl.stetdt..........f 182
                     +  ++++++ +       +++i+ia++++++ + n++ +  ++ + ++l ++ki+ ++ ++i + +i +++g  + l  + +++          +
     EEA22932.1 159 TGLIIQYWAQ-S------VSIGIFIAVFWVCItAANLLPVGFYGELEFWLSTVKIITIVGFMIFAICIDAGAGNRPYLgFHTWGNpgafapylleS 247
                    9999999653.4......57889999888875278********************76667777666666655555544533333345555554333 PP

  AA_permease_2 183 fpngwpgv..llgllivlwsfdGfesaanvsee..vkkkdvpkaifigllivlvlyllvniaflgvvpddei.....anlsnlgsvaalffeavgg 269
                    ++ + ++v  +++l ++ +s++G e +   + e  +++k++p ai   +  +l++++l+ +++   vp  +        ++ + s++ + ++ +g 
     EEA22932.1 248 TGPTAKFVgfWAVLIQAGFSYQGTELVGIAVGEceNPRKTMPSAIRKTFYRILLFFVLTIFFIGLLVPY-TNdrlasGGSDASASPFVIAADLAGV 342
                    3334443255999********************777779******988888888877775555555554.4334554445558899********** PP

  AA_permease_2 270 kvvaiivvilialsllgaintavigssrvlealardgvlPrffakvnkfgspiraiiltaivslillllfllas.saaynfllsvsslgliisyll 364
                    kv+ +i++ ++  ++l a+n+ v++ sr+l  la++g+ Prf++ ++++g p++++ +t ++ l+ +l ++  + s+ +n+ +++s ++ +is+ +
     EEA22932.1 343 KVLPGIINGVLLTVVLSAANSNVYSGSRILIGLAQEGFAPRFLKTTSAQGVPYYGVAVTSTIGLLAFLNLSN-NgSTVFNWFVNISGVAGFISWSV 437
                    ***************************************************************776655544.36*******************99 PP

  AA_permease_2 365 liigalilrkk...rphlkr.......pgkilvaiigalfllfll....valffppkgpatqssliyt.iilt 422
                    l  g+ i  ++    ++  r       ++ + +a+ g++f+++++    +++f+p+   + ++ ++y  +il+
     EEA22932.1 438 LN-GCHIAFMRalaARNISRdllpykaMWQPFFAWYGLFFNVLIIltqgFTAFIPTF-NVSSFFVAYIsLILF 508
                    85.444444331122233335775434333567777777777776555455565543.333333343334444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (556 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       654  (0.0364772); expected 358.6 (0.02)
Passed bias filter:                      224  (0.0124937); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.42
# Mc/sec: 4015.24
//
Query:       EEA22933.1  [L=367]
Description: 2-hydroxyacid dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    2.2e-42  144.4   0.0    2.4e-30  105.2   0.0    2.2  2  2-Hacid_dh_C   D-isomer specific 2-hydroxyacid dehydrogenase,
  ------ inclusion threshold ------
      0.029   14.9   0.0      0.072   13.7   0.0    1.7  1  F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
      0.056   13.6   0.0      0.097   12.8   0.0    1.4  1  NAD_binding_2  NAD binding domain of 6-phosphogluconate dehyd
       0.11   13.1   0.0       0.19   12.2   0.0    1.4  1  XdhC_C         XdhC Rossmann domain
       0.25   10.6   0.0       0.34   10.2   0.0    1.2  1  AlaDh_PNT_C    Alanine dehydrogenase/PNT, C-terminal domain


Domain annotation for each model (and alignments):
>> 2-Hacid_dh_C  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.0   0.0   5.7e-13     2e-09      33      76 ..     159     202 ..     132     211 .. 0.81
   2 !  105.2   0.0   6.6e-34   2.4e-30      83     178 .]     233     330 ..     223     330 .. 0.87

  Alignments for each domain:
  == domain 1  score: 37.0 bits;  conditional E-value: 5.7e-13
                   -GTTSEEEEES-SHHHHHHHHHHHHTT-EEEEESSSHHHHHCHH CS
  2-Hacid_dh_C  33 elsgktvGiiGlGrIGqavakrlkafgmkviaydrskkkeeeee 76 
                   + +++++Gi+G+G+IG++ a++++a+gm+++ay rs++k+ e +
    EEA22933.1 159 SSYRRRMGILGYGSIGRQCARIAQAMGMEIYAYTRSERKTPESR 202
                   567899******************************99877333 PP

  == domain 2  score: 105.2 bits;  conditional E-value: 6.6e-34
                   CSHHHHH.HH-SEEEE-S--STTTTTSBSHHHHHCSTTT.EEEEESS-GGGB-HHHHHHHHHTTSCCEEEES--SSSSSGTCHHHHHSTTEEE-SS- CS
  2-Hacid_dh_C  83 vsleell.aesDivslhlpltpetrhlinaeelakmkkg.ailiNtaRGglvdeeaLleaLksgkiagaalDvfeeeplpedspllelpnviltPHi 177
                   ++++++l ++ D++++ lplt++t++li+ ++++ + k+  ++ N+aRG  vd++aL+ aL++g+i+gaalDv+++eplp+++pl+++pnv++tPHi
    EEA22933.1 233 EDINAFLtQDLDVLVISLPLTKDTEKLISYKQFEILSKKkTFVSNVARGRHVDTQALISALDKGQIRGAALDVTDPEPLPKEHPLWKAPNVYITPHI 329
                   55555551568***********************8765505666****************************************************9 PP

                   T CS
  2-Hacid_dh_C 178 a 178
                   +
    EEA22933.1 330 S 330
                   6 PP

>> F420_oxidored  NADP oxidoreductase coenzyme F420-dependent
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0     2e-05     0.072       1      48 [.     164     228 ..     164     280 .. 0.65

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 2e-05
                    EEEEETTSHHHHHHHHHHHHTTS-GGCEEEEEESSCCCHHHHHHHHC.....................- CS
  F420_oxidored   1 kigiiGaGnmgealasgllaagaqpheivvansrnpekaeelaeelg.....................v 48 
                    ++gi+G+G++g+  a+ ++a g    ei+ a +r++ k  e +++                        
     EEA22933.1 164 RMGILGYGSIGRQCARIAQAMG---MEIY-AYTRSERKTPESRRDNTyhqfcvpgtgdpegiipskwfH 228
                    579*******************...****.889999998777644333455555555555555555552 PP

>> NAD_binding_2  NAD binding domain of 6-phosphogluconate dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   2.7e-05     0.097       2      87 ..     165     275 ..     164     299 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 2.7e-05
                    EEEE--SHHHHHHHHHHHHTT-EEEEE-SSHHHHHHHHHTT.......................EEE-SSHHHH.HHHCSEEEE-SSSHHHHHHHH CS
  NAD_binding_2   2 igfiGlGvMGsnmalnllkagykvavynrtkekveelvaeg.......................akaaesieel.vasldvvitmvkagkavdevi 73 
                    +g++G G +G++ a+  ++ g+++++y r++ k+ e   ++                           e+i+++ +++ldv ++ ++ +k+++++i
     EEA22933.1 165 MGILGYGSIGRQCARIAQAMGMEIYAYTRSERKTPESRRDNtyhqfcvpgtgdpegiipskwfhGASKEDINAFlTQDLDVLVISLPLTKDTEKLI 260
                    799******************************999888877888888888888888888876633334444441455688888888888888888 PP

                    HS.HCCC--TT-EEE CS
  NAD_binding_2  74 eg.llealkkgdili 87 
                    +   +e l+k ++++
     EEA22933.1 261 SYkQFEILSKKKTFV 275
                    766556666555555 PP

>> XdhC_C  XdhC Rossmann domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   5.4e-05      0.19       3      65 ..     167     293 ..     165     302 .. 0.67

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 5.4e-05
                 EE--STTHHHHHHHHHHHTEEEEEEES-GGGG.......-GGG-TT-SE.................................................. CS
      XdhC_C   3 ifGaghvaqalarlaaalgfrvtvvdpreefa.......tkerfpeade.................................................. 44 
                 i+G g +++++ar+a+a+g++++ +   e+ +       t                                                           
  EEA22933.1 167 ILGYGSIGRQCARIAQAMGMEIYAYTRSERKTpesrrdnT--------Yhqfcvpgtgdpegiipskwfhgaskedinafltqdldvlvislpltkdte 257
                 99*********************99988863334443330........134555555555555555555555556666666666666666666666666 PP

                 ...............-EEEE--S-HHHHHHHHHHHS CS
      XdhC_C  45 ...............tavvvlthdhklDaealeaal 65 
                                t+v  + ++ + D++al  al
  EEA22933.1 258 klisykqfeilskkkTFVSNVARGRHVDTQALISAL 293
                 666667777777777788888888888888887777 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0   9.4e-05      0.34      19      64 ..     153     198 ..     138     271 .. 0.80

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 9.4e-05
                  TTCEETCB---EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHHHH CS
  AlaDh_PNT_C  19 laGgvpgvepakvlviGgGvaGlqAiatakglgakVtvlDvrparl 64 
                  l + v+   + ++ ++G G  G q +++a+++g +++++  ++++ 
   EEA22933.1 153 LFSNVESSYRRRMGILGYGSIGRQCARIAQAMGMEIYAYTRSERKT 198
                  66777777888999***********************997766554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (367 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       327  (0.0182386); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.51u 0.25s 00:00:00.76 Elapsed: 00:00:00.44
# Mc/sec: 2504.39
//
Query:       EEA22934.1  [L=706]
Description: AMP-binding enzyme, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.3e-83  281.0   0.0    1.7e-83  280.6   0.0    1.1  1  AMP-binding  AMP-binding enzyme
  ------ inclusion threshold ------
        0.1   12.5   0.2        2.1    8.4   0.0    2.7  2  DUF1658      Protein of unknown function (DUF1658)


Domain annotation for each model (and alignments):
>> AMP-binding  AMP-binding enzyme
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  280.6   0.0   1.9e-87   1.7e-83      10     422 ..      84     553 ..      67     554 .. 0.84

  Alignments for each domain:
  == domain 1  score: 280.6 bits;  conditional E-value: 1.9e-87
                  TSEEEEECCSTEEEEHHHHHHHHHHHHHHHHHTTSSTT-E.....EEEEESSSHHHHHHHHHHHHTT-EEEEEETTS-HHHHHHHHHHHTESEEEETC CS
  AMP-binding  10 dkvalvdsgegqtlTYreldervnrlAagLrslGvkkgdr.....VaillpnspewvvallailkaGavvvplnptltaeelayiledseakvliatv 102
                  d++   + g +q++ Y+ +++r  +l+ gL +l  k+g       V+++++n+pew +++la+ + ++  v l++ l+a++ +yi++++e  +++  +
   EEA22934.1  84 DATTKSF-GPYQWIDYQTVQRRRANLGVGLVELHKKHGHPggkhgVGLWCQNRPEWQITDLACTSQSLYSVSLYDVLGADTTEYIINHAELACVV--T 178
                  5555555.78********************976555555455559**************************************************..8 PP

                  TCCCHHHHHHHHSCC-EECEEEEESCCS-HCCHCCCHCCCCSCTTS...................-TSCCCS-BTTSEEEEEEE--SSSS-EEEEEEH CS
  AMP-binding 103 dselleklleaaakleavklvivldadellkeeelkeeeeseekae...................kpeeeeelkpddlayiiYTSGTTGkPKGVmlsh 181
                  +   ++ l + ++kl+  k +++ld  + +++  l +++  +e a                    k ++ ++++p+d+++i YTSGTTG PKGV+l h
   EEA22934.1 179 SLPHVPTLIKLKPKLPGLKFIVCLDPLDGNEQPGLSKRTLLNEMASgmdltiysmdeveelgaslK-RPYNPPTPEDVVTINYTSGTTGPPKGVVLLH 275
                  8777999******************8777777666666665554426789999***********63.35668************************** PP

                  HHHHHHHHHHHHHHC.SCCTTT-EEEESS-TTSCHHHHHHHHHHHHTT-EEEE-TTCGCCHHHHHHHHHHHHT-SEEEEEHHHHHHH........HHC CS
  AMP-binding 182 rnlvanvaslkletr.fklkeddvvlsilplahifglilelllallsGatvvllpkdaaldpklllelieklkvtviagvPrvleal........les 270
                  +n++++++  ++  + ++  ++dv ls+lplahi++  l + +++ +G+ +++++++       l++++++l++t +++vPr++ ++        +++
   EEA22934.1 276 KNAISALSV-SIIVTkWG--NTDVALSYLPLAHIMER-LVEQASFWAGGGLGYYHGEIL----ELVDDLKTLRPTAFVSVPRLYTRFagavrtatVDA 365
                  ***999555.64444244..78**************6.*****************9988....368*********************77766655332 PP

                  CCHHCHHHHC....................................CGTT-SEEEEESS-EBHHHHHHHHHHHTCEEEEEEEEGGGSSECEECHCTTT CS
  AMP-binding 271 galkaakkak....................................dlsslrlvllggeplspellrffralfgeevlegYGlTEttgvvtvlpleed 332
                  + ++ a +++                                     + ++r + +g +pl p++  f+ra++g ++++gYGlTE  ++++ +++ ed
   EEA22934.1 366 PGFRGALSRHvlstklanlenpdttnttekhaiydriwtrkvaaalGMDRVRSMASGSAPLDPSIHNFMRAVTGASFVQGYGLTESYAMAI-VQNVED 462
                  22221333334444455555555555555556666666666666655558999*************************************9.775666 PP

                  CTSTTS-BEE-TTEEEEEE-TTTSCBEETTSE...EEEEEEETTS-SEBTT-HHHHHHHEEETCCEEEEEEEEEEETTSEEEEEEECCCEEEE CS
  AMP-binding 333 kkklgsvGkplpgvevkivDeetgepvpdgee...GellvrgpgvmkgYlkkpeataeafdsegrwlrTGDlgrldedGyleivgRkkdlikl 422
                   ++++ +G + pg+e+ +v   ++e++ d+++   Gell+rg+++++ Ylk+pe+ta af+ e++w+rTGD++++de G+++i++R k+++kl
   EEA22934.1 463 -RSVNNCGAISPGIEACLVSIPDMEYFVDDKPlprGELLLRGNHIFREYLKNPEETAAAFT-EDGWFRTGDICTIDELGRFRIIDRRKNVLKL 553
                  .57788**********************999999**************************9.867**************************98 PP

>> DUF1658  Protein of unknown function (DUF1658)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.4   0.0   0.00024       2.1       4      14 ..      74     119 ..      72     124 .. 0.60
   2 ?    0.6   0.0     0.071   6.3e+02       2      11 ..     335     344 ..     334     346 .. 0.88

  Alignments for each domain:
  == domain 1  score: 8.4 bits;  conditional E-value: 0.00024
     DUF1658   4 KTrriPARPs...................................H 14 
                 K+r++++RP                                    H
  EEA22934.1  74 KSRCLGRRPYdattksfgpyqwidyqtvqrrranlgvglvelhkkH 119
                 7********6555555555555555555555555555555555555 PP

  == domain 2  score: 0.6 bits;  conditional E-value: 0.071
     DUF1658   2 klKTrriPAR 11 
                 +lKT+r+ A+
  EEA22934.1 335 DLKTLRPTAF 344
                 89****9886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (706 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       288  (0.0160634); expected 358.6 (0.02)
Passed bias filter:                      279  (0.0155614); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.27s 00:00:00.82 Elapsed: 00:00:00.43
# Mc/sec: 4955.46
//
Query:       EEA22935.1  [L=270]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.1e-31  108.0   0.0    4.2e-31  107.6   0.0    1.2  1  DUF2012   Protein of unknown function (DUF2012)


Domain annotation for each model (and alignments):
>> DUF2012  Protein of unknown function (DUF2012)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  107.6   0.0   2.3e-35   4.2e-31       1     123 []      37     178 ..      37     178 .. 0.96

  Alignments for each domain:
  == domain 1  score: 107.6 bits;  conditional E-value: 2.3e-35
     DUF2012   1 knplnllantrvlL.......dsgqqrkfkalvrrDGsFifrdlpeg...sYlLevespeyvFepyrVdvkdkgkakasklrivetaevnvvdesgne. 88 
                 +np  l++nt+++L       + +q++ ++++++  ++F f+dlp+    sYlL+++s ey+F+p rVd++    a++++l+i+et+++n++d++g e 
  EEA22935.1  37 PNPHVLPPNTHATLttlpsslSPDQKHVISTPLTDTAEFHFSDLPSTgaeSYLLDIRSKEYIFAPCRVDIA----ADGTVLGIWETFRGNQWDNRGLEr 131
                 578899********7766666669*********************98899*********************....************************ PP

     DUF2012  89 ............esyplkikavarreyyeerekfsilsLlknPmvLl 123
                             +++ +++k++a+r++yeer kfs+l LlknPm+L+
  EEA22935.1 132 ytklksqeglrdVDVVVQAKVLAKRGFYEERPKFSPLTLLKNPMILM 178
                 **********************************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (270 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       294  (0.016398); expected 358.6 (0.02)
Passed bias filter:                      241  (0.0134419); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.35s 00:00:00.95 Elapsed: 00:00:00.57
# Mc/sec: 1438.19
//
Query:       EEA22936.1  [L=237]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.6e-18   65.4   0.0    8.4e-18   64.8   0.0    1.2  1  Peptidase_M24  Metallopeptidase family M24
  ------ inclusion threshold ------
      0.097   12.0   0.0       0.14   11.4   0.0    1.1  1  Mu-like_gpT    Mu-like prophage major head subunit gpT


Domain annotation for each model (and alignments):
>> Peptidase_M24  Metallopeptidase family M24
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.8   0.0   9.3e-22   8.4e-18       7     166 ..      16     184 ..      10     210 .. 0.77

  Alignments for each domain:
  == domain 1  score: 64.8 bits;  conditional E-value: 9.3e-22
                    HHHHHHHHHHHHHH.HHTTCBHHHHHHHHHHHHHHHTTTCEESSSSEEEEGGGGGSTTT.BCSSSB--TTEEEEEEEEEEETTEEEEEEEEEECSS CS
  Peptidase_M24   7 ariasaaleavlea.ikpgvterelaaeieattlkrhgarglafppivasgenaavlhy.tpndrvlkegdlvlidagaeydgyasDitrTvlvGk 100
                     + a + ++++ +  i+pgv+e+ l +ei+a  ++r ++r ++++  + sg+n+  +   +p dr ++e+d++++d+g++++++ +D +rT+++G+
     EEA22936.1  16 EQKAIQLFTEIERTlIRPGVSEKTLSDEIHALGVERFNVRTHWHKRLIRSGPNTLRPFDdNPPDRIIEEDDILVVDLGPVFEEWEADFGRTYVLGN 111
                    555666777786545***************9999*********************99998888********************************4 PP

                    GSHH......HHHHHHHHHHHHH..HHHHC-STTSBHHHHHHHHHHHHHHTTBCCGBSSCSEEEESSSSSEEEE CS
  Peptidase_M24 101 ftpe......qrelyeavleaqe..aaikavkpGvtlseidaaarevlesaglakffphglGHgvGlevhdegp 166
                    + ++       + ++  v++  +  + +k   +Gvt++e++a a+e++e+ag+ kf     GH vG   h+  p
     EEA22936.1 112 DPKKillrdaLEPIWFQVKDWYYqqQSTKTGDEGVTGEELYAYACETAEKAGF-KFGAPIAGHIVGSFPHERIP 184
                    433244222222244444443322255555568********************.99999*******88887644 PP

>> Mu-like_gpT  Mu-like prophage major head subunit gpT
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   1.6e-05      0.14     163     209 ..     120     166 ..     115     170 .. 0.94

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 1.6e-05
  Mu-like_gpT 163 ralkPlifQeRkapelvkldkeedekvfmkkeylygvdaRanvGfgl 209
                   al P+ fQ +  +  ++ +k+ de v  ++ y+y++++  ++Gf +
   EEA22936.1 120 DALEPIWFQVKDWYYQQQSTKTGDEGVTGEELYAYACETAEKAGFKF 166
                  699******************************************87 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (237 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       291  (0.0162307); expected 358.6 (0.02)
Passed bias filter:                      275  (0.0153383); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.36s 00:00:00.92 Elapsed: 00:00:00.54
# Mc/sec: 1311.87
//
Query:       EEA22937.1  [L=1165]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.7e-65  216.2   9.6    3.9e-12   46.6   0.2    9.6  9  Ank_2     Ankyrin repeats (3 copies)
    1.6e-54  181.6   6.4    2.1e-07   31.4   0.0   12.2 12  Ank_4     Ankyrin repeats (many copies)
    2.3e-42  138.1  12.9    0.00065   20.0   0.0   16.3 16  Ank_3     Ankyrin repeat
    5.3e-30  102.5  14.2    0.00069   20.0   0.0   13.9 14  Ank       Ankyrin repeat
    6.5e-29   99.6  18.1      0.042   14.2   0.1   12.7 13  Ank_5     Ankyrin repeats (many copies)
    1.2e-15   57.5   0.3      3e-15   56.2   0.3    1.8  1  Clr5      Clr5 domain


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.0     0.031        92      25      76 ..     342     408 ..     305     428 .. 0.51
   2 !   37.3   0.0   1.1e-12   3.2e-09      10      81 ..     446     530 ..     441     531 .. 0.84
   3 !    8.5   0.0   0.00098       2.9      27      49 ..     562     587 ..     547     615 .. 0.66
   4 !   29.1   0.0   3.7e-10   1.1e-06      24      81 ..     624     695 ..     597     697 .. 0.73
   5 !   46.6   0.2   1.3e-15   3.9e-12      25      80 ..     701     764 ..     693     767 .. 0.83
   6 !   24.2   0.0   1.2e-08   3.6e-05       4      80 ..     778     861 ..     774     866 .. 0.80
   7 !    9.1   0.0   0.00064       1.9      28      78 ..     836     897 ..     832     901 .. 0.71
   8 !   30.8   0.0   1.1e-10   3.2e-07      13      82 ..     972    1051 ..     957    1052 .. 0.86
   9 !   31.8   0.1   5.3e-11   1.6e-07      22      75 ..    1054    1114 ..    1050    1121 .. 0.80

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.031
       Ank_2  25 ngktaLhyAakngnleivklLleh...............adndgrtpLhyAarsghleivklLlekg 76 
                 + + +L +++ +gn+++v+ +l+                a++  +  + +A++ + +++++lL+e g
  EEA22937.1 342 FMRKILPASVNSGNTKLVEEILNRafvsrtrhdndlpldAEYLQEYCITIAVQRQDQRMLQLLCEAG 408
                 5566666666666666666666522333332233333222233444555555554455555555444 PP

  == domain 2  score: 37.3 bits;  conditional E-value: 1.1e-12
       Ank_2  10 lelvklLl.egadpn....k.ngktaLhyAakngnleivklLleh.......adndgrtpLhyAarsghleivklLlekgadinl 81 
                 l++++ L+ +gadp+    + +  ++L+ Aa+ gnl +v +Ll++       ++++  tpL++A+  ++ ++v++L+ kgad+n+
  EEA22937.1 446 LDILQTLIsFGADPDgmlvNvERGFPLINAAELGNLAAVDMLLKAgsrvnsyVRDYFGTPLQAAVYANQAKMVEFLIAKGADVNA 530
                 469999********9876548677*******************9666744553355559******99****************96 PP

  == domain 3  score: 8.5 bits;  conditional E-value: 0.00098
       Ank_2  27 ktaLhyAakngnleivklLleh...a 49 
                 kt++++A++ +n  +v+lLl++   +
  EEA22937.1 562 KTPIQIACEMNNMSLVELLLANgalV 587
                 56666666666555566666544432 PP

  == domain 4  score: 29.1 bits;  conditional E-value: 3.7e-10
       Ank_2  24 k.ngktaLhyAakng...nlei..vklLleh.ad.......ndgrtpLhyAarsghleivklLlekgadinl 81 
                 + n kt+L+y a +    +++i  +  Ll++ a+       n g tpL++Aar +++eiv +L+e+ga++n+
  EEA22937.1 624 SpNYKTILYYTAFQHsvqHRNIflLYRLLSQgANpdsriipNWGDTPLQMAARLNYPEIVSILMENGANVNA 695
                 1467899997777642336677544555554544335577788**************************996 PP

  == domain 5  score: 46.6 bits;  conditional E-value: 1.3e-15
       Ank_2  25 ngktaLhyAakngnleivklLl.eh..ad.....ndgrtpLhyAarsghleivklLlekgadin 80 
                 ng+taL++Aa++gn+e+v+lLl ++  ++     + g t+L++A+++gh+++++lLl+++adi+
  EEA22937.1 701 NGRTALQAAAESGNIEMVQLLLfSNadVNapagyERGLTALQAAIKNGHFDVAELLLKSNADIH 764
                 8*********************53345335566777*********************999**97 PP

  == domain 6  score: 24.2 bits;  conditional E-value: 1.2e-08
       Ank_2   4 Aakn.gnlelvklLl.egadpnkngktaLhyAakngnleivklLleh...ad..ndgr.tpLhyAarsghleivklLlekgadin 80 
                 Aa + +nl+++++L  +g+  + +   a+ +Aa++  +e +++Ll+h   ++  +d + +pL +++ +++l ++k+Lle+ga+++
  EEA22937.1 778 AAASgKNLSMLEFLTkNGSGGR-ESVPAICAAAEYSWVEGARYLLQHgsdVNsvCDDYiSPLAWSITKQNLAMMKFLLESGANLK 861
                 333425889*****97665533.45788889999999999******9977557866666**********************9976 PP

  == domain 7  score: 9.1 bits;  conditional E-value: 0.00064
       Ank_2  28 taLhyAakngnleivklLleh.......ad....ndgrtpLhyAars.ghleivklLlekgad 78 
                 ++L +++ ++nl ++k+Lle        ++       + +L +A+++    ei+ +L+ ++a+
  EEA22937.1 836 SPLAWSITKQNLAMMKFLLESganlklpMKeelcV-YNDALCFAIEQrCPREIIFFLCHHYAK 897
                 78999999999999999998564444541145532.446999999986567999999876665 PP

  == domain 8  score: 30.8 bits;  conditional E-value: 1.1e-10
       Ank_2   13 vklLl.egadpn..kngktaLhyAakngnleivklLleh........adndgrtpLhyAarsghleivklLlekgadinlk 82  
                  +k+Ll  gad+n  ++g taL+ A+++g++ ++k+Ll++        + +   tpL+ A+    le++  Lle+gad+n+ 
  EEA22937.1  972 FKILLeMGADVNmyEDGPTALQSAIHAGQIGLAKYLLDEgaeiqvpaV-EFTGTPLQEAIAIEELELAYTLLERGADVNAS 1051
                  68999999****855*************8888*****97755555432.55679******7799**************975 PP

  == domain 9  score: 31.8 bits;  conditional E-value: 5.3e-11
       Ank_2   22 pnkngktaLhyAakngnleivklLle...h...ad..ndgrtpLhyAarsghleivklLlek 75  
                  pn  g+taL++Aa+ gn++i+  Ll    h   a+  ++grt++ +Aa++g++++++lLl++
  EEA22937.1 1054 PN-GGLTALQTAAETGNINIAVELLRrgaHvvvATapQYGRTAITAAACYGREDMLQLLLDH 1114
                  44.68***************6555542544887446899*********************87 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.0       0.3   8.9e+02      10      54 ..     352     404 ..     344     405 .. 0.70
   2 ?   -0.1   0.0       0.5   1.5e+03      14      28 ..     446     460 ..     443     463 .. 0.89
   3 !   21.2   0.0     1e-07   0.00031       4      55 .]     471     522 ..     471     531 .. 0.95
   4 !    8.9   0.0   0.00077       2.3       3      30 ..     563     590 ..     561     599 .. 0.77
   5 !   15.4   0.0   7.1e-06     0.021       9      53 ..     640     685 ..     632     686 .. 0.85
   6 !   29.0   0.0   3.8e-10   1.1e-06       8      55 .]     674     722 ..     673     722 .. 0.91
   7 !   31.4   0.0   6.9e-11   2.1e-07       2      54 ..     738     791 ..     724     792 .. 0.97
   8 !   20.0   0.0   2.6e-07   0.00077       4      55 .]     804     854 ..     802     854 .. 0.94
   9 !   15.7   0.0   5.8e-06     0.017      18      55 .]     973    1008 ..     956    1008 .. 0.91
  10 !   23.2   0.0   2.4e-08   7.3e-05       3      51 ..    1024    1073 ..    1022    1077 .. 0.89
  11 !    7.3   0.1    0.0024       7.1       2      23 ..    1093    1114 ..    1092    1146 .. 0.68
  12 ?   -1.7   0.0       1.7     5e+03       7      25 ..    1132    1150 ..    1128    1155 .. 0.75

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.3
       Ank_4  10 isgrlelvrlLlekgadinaq..dnrs.......GetalhiAakrgnveilklL 54 
                 +sg+++lv+ +l ++a + ++  dn+        +e ++ iA++r + ++l+lL
  EEA22937.1 352 NSGNTKLVEEIL-NRAFVSRTrhDNDLpldaeylQEYCITIAVQRQDQRMLQLL 404
                 488889999988.56666666443322444555688899999999999999887 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.5
       Ank_4  14 lelvrlLlekgadin 28 
                 l++++ L+++gad++
  EEA22937.1 446 LDILQTLISFGADPD 460
                 899**********87 PP

  == domain 3  score: 21.2 bits;  conditional E-value: 1e-07
       Ank_4   4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 +L +aa+ g+l +v+ Ll  g  +n    ++  t+l+ A++ ++ +++++L+
  EEA22937.1 471 PLINAAELGNLAAVDMLLKAGSRVNSYVRDYFGTPLQAAVYANQAKMVEFLI 522
                 6889**************999999999788999******************8 PP

  == domain 4  score: 8.9 bits;  conditional E-value: 0.00077
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaq 30 
                 t++  a++++++ lv+lLl++ga ++ +
  EEA22937.1 563 TPIQIACEMNNMSLVELLLANGALVDLS 590
                 6788899999999999999998776655 PP

  == domain 5  score: 15.4 bits;  conditional E-value: 7.1e-06
       Ank_4   9 aisgrlelvrlLlekgadinaq.dnrsGetalhiAakrgnveilkl 53 
                 +++ ++ l+ +Ll++ga+++ + +++ G+t+l++Aa+ +++ei+  
  EEA22937.1 640 VQHRNIFLLYRLLSQGANPDSRiIPNWGDTPLQMAARLNYPEIVSI 685
                 45889999999*************************9999998865 PP

  == domain 6  score: 29.0 bits;  conditional E-value: 3.8e-10
       Ank_4   8 aaisgrlelvrlLlekgadinaqdnrs..GetalhiAakrgnveilklLl 55 
                 aa  +  e+v +L e+ga++na  +++  G+tal+ Aa  gn+e+++lLl
  EEA22937.1 674 AARLNYPEIVSILMENGANVNAP-PGRvnGRTALQAAAESGNIEMVQLLL 722
                 777888999*************8.96666********************8 PP

  == domain 7  score: 31.4 bits;  conditional E-value: 6.9e-11
       Ank_4   2 ltaLhyaaisgrlelvrlLlekgadinaq.dnrsGetalhiAakrgnveilklL 54 
                 ltaL +a++ g++++++lLl ++adi+a  ++r+G++a+  Aa++ n+++l++L
  EEA22937.1 738 LTALQAAIKNGHFDVAELLLKSNADIHAPpSPRYGLSAIAAAASGKNLSMLEFL 791
                 89***************************999*********************9 PP

  == domain 8  score: 20.0 bits;  conditional E-value: 2.6e-07
       Ank_4   4 aLhyaaisgrlelvrlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55 
                 a+ +aa+++ +e +r+Ll++g d+n +  ++  ++l   + + n+ + k+Ll
  EEA22937.1 804 AICAAAEYSWVEGARYLLQHGSDVNSV-CDDYISPLAWSITKQNLAMMKFLL 854
                 7889999********************.788********************8 PP

  == domain 9  score: 15.7 bits;  conditional E-value: 5.8e-06
       Ank_4   18 rlLlekgadinaqdnrsGetalhiAakrgnveilklLl 55  
                  ++Lle gad+n+   ++G tal+ A+  g++  +k+Ll
  EEA22937.1  973 KILLEMGADVNMY--EDGPTALQSAIHAGQIGLAKYLL 1008
                  7899********8..99********************8 PP

  == domain 10  score: 23.2 bits;  conditional E-value: 2.4e-08
       Ank_4    3 taLhyaaisgrlelvrlLlekgadinaq.dnrsGetalhiAakrgnveil 51  
                  t+L  a++ + lel+  Lle+gad+na+ +++ G+tal+ Aa +gn++i+
  EEA22937.1 1024 TPLQEAIAIEELELAYTLLERGADVNASaAPNGGLTALQTAAETGNINIA 1073
                  6777888888999999*************9****************9987 PP

  == domain 11  score: 7.3 bits;  conditional E-value: 0.0024
       Ank_4    2 ltaLhyaaisgrlelvrlLlek 23  
                  +ta+ +aa +gr+++++lLl++
  EEA22937.1 1093 RTAITAAACYGREDMLQLLLDH 1114
                  788888888***********85 PP

  == domain 12  score: -1.7 bits;  conditional E-value: 1.7
       Ank_4    7 yaaisgrlelvrlLlekga 25  
                  +a + g+ e++++L e+++
  EEA22937.1 1132 WAEATGHPEIAAWLREYRV 1150
                  5666788899999988876 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.0      0.35   1.1e+03      14      30 ..     445     460 ..     442     461 .. 0.87
   2 ?    4.7   0.0      0.02        61       5      30 ..     471     495 ..     470     496 .. 0.87
   3 !   14.9   0.0   9.5e-06     0.028       4      31 .]     504     530 ..     503     530 .. 0.96
   4 !   10.9   0.1   0.00019      0.58       4      29 ..     563     587 ..     562     589 .. 0.90
   5 ?   -1.1   0.0       1.6   4.6e+03       3      30 ..     633     659 ..     631     660 .. 0.88
   6 !   16.4   0.0     3e-06     0.009       2      31 .]     667     695 ..     666     695 .. 0.95
   7 !   20.0   0.0   2.2e-07   0.00065       1      31 []     701     730 ..     701     730 .. 0.96
   8 !   14.9   0.0   9.4e-06     0.028       2      31 .]     737     765 ..     736     765 .. 0.94
   9 ?    0.2   0.0      0.58   1.7e+03       1      26 [.     771     795 ..     771     797 .. 0.82
  10 ?    3.5   0.0      0.05   1.5e+02       9      30 ..     808     828 ..     806     829 .. 0.85
  11 !    6.5   0.0    0.0051        15       2      29 ..     834     860 ..     833     862 .. 0.90
  12 ?    0.8   0.0      0.39   1.2e+03      18      31 .]     972     984 ..     955     984 .. 0.84
  13 !    6.3   0.0    0.0063        19       2      29 ..     988    1014 ..     987    1016 .. 0.90
  14 !    6.8   0.0    0.0042        13       4      31 .]    1024    1050 ..    1022    1050 .. 0.96
  15 !    8.6   0.0    0.0011       3.3       2      29 ..    1057    1083 ..    1056    1085 .. 0.93
  16 !    9.4   0.0   0.00061       1.8       1      25 [.    1091    1115 ..    1091    1117 .. 0.93

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.35
       Ank_3  14 nleivkfLlenkgadvn 30 
                 +l+i++ L+  +gad++
  EEA22937.1 445 SLDILQTLIS-FGADPD 460
                 5689******.****97 PP

  == domain 2  score: 4.7 bits;  conditional E-value: 0.02
       Ank_3   5 pLhlAarsgnleivkfLlenkgadvn 30 
                 pL  Aa+ gnl+ v++Ll+  g  vn
  EEA22937.1 471 PLINAAELGNLAAVDMLLK-AGSRVN 495
                 7899**************9.676655 PP

  == domain 3  score: 14.9 bits;  conditional E-value: 9.5e-06
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadvna 31 
                 tpL  A+ ++  ++v+fL+  kgadvna
  EEA22937.1 504 TPLQAAVYANQAKMVEFLIA-KGADVNA 530
                 9*******************.9****96 PP

  == domain 4  score: 10.9 bits;  conditional E-value: 0.00019
       Ank_3   4 tpLhlAarsgnleivkfLlenkgadv 29 
                 tp+ +A++ +n ++v++Ll  +ga v
  EEA22937.1 563 TPIQIACEMNNMSLVELLLA-NGALV 587
                 9*******************.79865 PP

  == domain 5  score: -1.1 bits;  conditional E-value: 1.6
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvn 30 
                 +t++ + + + n+ ++  Ll   ga+++
  EEA22937.1 633 YTAFQHSVQHRNIFLLYRLLS-QGANPD 659
                 899999999999999999**9.899986 PP

  == domain 6  score: 16.4 bits;  conditional E-value: 3e-06
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvna 31 
                 G tpL +Aar + +eiv  L e +ga+vna
  EEA22937.1 667 GDTPLQMAARLNYPEIVSILME-NGANVNA 695
                 89********************.8****96 PP

  == domain 7  score: 20.0 bits;  conditional E-value: 2.2e-07
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkgadvna 31 
                 nG+t+L  Aa+sgn+e+v++Ll   +advna
  EEA22937.1 701 NGRTALQAAAESGNIEMVQLLLF-SNADVNA 730
                 7**********************.8****96 PP

  == domain 8  score: 14.9 bits;  conditional E-value: 9.4e-06
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadvna 31 
                 G t+L  A+++g+++++++Ll+  +ad++a
  EEA22937.1 737 GLTALQAAIKNGHFDVAELLLK-SNADIHA 765
                 89********************.8***985 PP

  == domain 9  score: 0.2 bits;  conditional E-value: 0.58
       Ank_3   1 nGetpLhlAarsgnleivkfLlenkg 26 
                 +G +++  Aa+  nl++++fL + +g
  EEA22937.1 771 YGLSAIAAAASGKNLSMLEFLTK-NG 795
                 5778888899999999*****88.44 PP

  == domain 10  score: 3.5 bits;  conditional E-value: 0.05
       Ank_3   9 AarsgnleivkfLlenkgadvn 30 
                 Aa++  +e +++Ll+ +g dvn
  EEA22937.1 808 AAEYSWVEGARYLLQ-HGSDVN 828
                 6777778889*****.9****9 PP

  == domain 11  score: 6.5 bits;  conditional E-value: 0.0051
       Ank_3   2 GetpLhlAarsgnleivkfLlenkgadv 29 
                 + +pL + +  +nl+++kfLle  ga++
  EEA22937.1 834 YISPLAWSITKQNLAMMKFLLE-SGANL 860
                 5799******************.89987 PP

  == domain 12  score: 0.8 bits;  conditional E-value: 0.39
       Ank_3  18 vkfLlenkgadvna 31 
                  k Lle +gadvn+
  EEA22937.1 972 FKILLE-MGADVNM 984
                 5789**.*****95 PP

  == domain 13  score: 6.3 bits;  conditional E-value: 0.0063
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadv 29  
                  G t+L  A+++g + ++k+Ll+  ga++
  EEA22937.1  988 GPTALQSAIHAGQIGLAKYLLD-EGAEI 1014
                  78********************.79987 PP

  == domain 14  score: 6.8 bits;  conditional E-value: 0.0042
       Ank_3    4 tpLhlAarsgnleivkfLlenkgadvna 31  
                  tpL +A+    le++  Lle +gadvna
  EEA22937.1 1024 TPLQEAIAIEELELAYTLLE-RGADVNA 1050
                  9*******************.*****96 PP

  == domain 15  score: 8.6 bits;  conditional E-value: 0.0011
       Ank_3    2 GetpLhlAarsgnleivkfLlenkgadv 29  
                  G t+L +Aa+ gn++i+  Ll+ +ga v
  EEA22937.1 1057 GLTALQTAAETGNINIAVELLR-RGAHV 1083
                  89********************.99976 PP

  == domain 16  score: 9.4 bits;  conditional E-value: 0.00061
       Ank_3    1 nGetpLhlAarsgnleivkfLlenk 25  
                  +G+t++  Aa +g+ +++++Ll+++
  EEA22937.1 1091 YGRTAITAAACYGREDMLQLLLDHY 1115
                  79*********************75 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.17   5.2e+02      14      28 ..     445     460 ..     425     465 .. 0.76
   2 !   12.4   0.0   5.7e-05      0.17       4      29 ..     504     530 ..     504     531 .. 0.92
   3 !    6.7   0.0    0.0035        10       4      25 ..     563     585 ..     562     590 .. 0.87
   4 ?   -0.4   0.0      0.62   1.9e+03      21      29 ..     651     660 ..     629     662 .. 0.79
   5 !   20.0   0.0   2.3e-07   0.00069       2      29 ..     667     695 ..     666     696 .. 0.95
   6 !   18.2   0.0   8.4e-07    0.0025       1      29 [.     701     730 ..     701     731 .. 0.95
   7 !   13.3   0.1     3e-05     0.089       2      29 ..     737     765 ..     736     766 .. 0.92
   8 ?    0.9   0.0      0.25   7.5e+02      19      30 ..     818     830 ..     805     832 .. 0.87
   9 ?    2.9   0.0     0.056   1.7e+02       4      27 ..     836     860 ..     833     863 .. 0.86
  10 ?   -1.9   0.0       1.9   5.7e+03      19      28 ..     973     983 ..     972     984 .. 0.81
  11 ?    4.7   0.0     0.015        45       1      28 [.     987    1015 ..     987    1018 .. 0.80
  12 ?    2.1   0.0       0.1     3e+02       4      29 ..    1024    1050 ..    1024    1051 .. 0.75
  13 ?    3.7   0.1     0.032        97       2      26 ..    1057    1082 ..    1056    1087 .. 0.89
  14 !    7.4   0.0    0.0021       6.2       1      23 [.    1091    1114 ..    1091    1121 .. 0.89

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.17
                 THHHHHHHH.TTTSTT CS
         Ank  14 kkriiklLL.hGAnln 28 
                 +++i++ L+  GA+++
  EEA22937.1 445 SLDILQTLIsFGADPD 460
                 366******66***96 PP

  == domain 2  score: 12.4 bits;  conditional E-value: 5.7e-05
                 BHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnlna 29 
                 TPL  A++ +++ ++++L+ +GA++na
  EEA22937.1 504 TPLQAAVYANQAKMVEFLIaKGADVNA 530
                 9******888899******99*****8 PP

  == domain 3  score: 6.7 bits;  conditional E-value: 0.0035
                 BHHHHHHHHTTHHHHHHHH.TTT CS
         Ank   4 TPLHlAatngkkriiklLL.hGA 25 
                 TP  +A+  ++ + ++lLL +GA
  EEA22937.1 563 TPIQIACEMNNMSLVELLLaNGA 585
                 99*****9999********9998 PP

  == domain 4  score: -0.4 bits;  conditional E-value: 0.62
                 HH.TTTSTTC CS
         Ank  21 LL.hGAnlna 29 
                 LL +GAn+++
  EEA22937.1 651 LLsQGANPDS 660
                 7888****97 PP

  == domain 5  score: 20.0 bits;  conditional E-value: 2.3e-07
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlna 29 
                 G+TPL +Aa+ + ++i++ L  +GAn+na
  EEA22937.1 667 GDTPLQMAARLNYPEIVSILMeNGANVNA 695
                 9********************99*****8 PP

  == domain 6  score: 18.2 bits;  conditional E-value: 8.4e-07
                 TSBBHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   1 dGnTPLHlAatngkkriiklLL.hGAnlna 29 
                 +G+T+L  Aa  g+ ++++lLL + A++na
  EEA22937.1 701 NGRTALQAAAESGNIEMVQLLLfSNADVNA 730
                 7*********99**********989****8 PP

  == domain 7  score: 13.3 bits;  conditional E-value: 3e-05
                 SBBHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank   2 GnTPLHlAatngkkriiklLL.hGAnlna 29 
                 G T+L  A+ ng+ ++++lLL + A+++a
  EEA22937.1 737 GLTALQAAIKNGHFDVAELLLkSNADIHA 765
                 89*******************778**987 PP

  == domain 8  score: 0.9 bits;  conditional E-value: 0.25
                 HHHH.TTTSTTCB CS
         Ank  19 klLL.hGAnlnal 30 
                 ++LL hG+++n++
  EEA22937.1 818 RYLLqHGSDVNSV 830
                 78**99****975 PP

  == domain 9  score: 2.9 bits;  conditional E-value: 0.056
                 BHHHHHHHHTTHHHHHHHH.TTTST CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnl 27 
                 +PL + +t  ++ + k+LL +GAnl
  EEA22937.1 836 SPLAWSITKQNLAMMKFLLeSGANL 860
                 6888888888899******99***8 PP

  == domain 10  score: -1.9 bits;  conditional E-value: 1.9
                 HHHH.TTTSTT CS
         Ank  19 klLL.hGAnln 28 
                 k LL  GA++n
  EEA22937.1 973 KILLeMGADVN 983
                 679977****9 PP

  == domain 11  score: 4.7 bits;  conditional E-value: 0.015
                  TSBBHHHHHH...HHTTHHHHHHHH.TTTSTT CS
         Ank    1 dGnTPLHlAa...tngkkriiklLL.hGAnln 28  
                  dG T+L  A+   ++g    +k+LL  GA+++
  EEA22937.1  987 DGPTALQSAIhagQIG---LAKYLLdEGAEIQ 1015
                  6669******555555...******77**986 PP

  == domain 12  score: 2.1 bits;  conditional E-value: 0.1
                  BHHHHHHHHTTHHHHHHHH.TTTSTTC CS
         Ank    4 TPLHlAatngkkriiklLL.hGAnlna 29  
                  TPL  A+ +  ++ +  LL +GA++na
  EEA22937.1 1024 TPLQEAIAIEELELAYTLLeRGADVNA 1050
                  777777766656667679*88*****8 PP

  == domain 13  score: 3.7 bits;  conditional E-value: 0.032
                  SBBHHHHHHHHTTHHHHHHHH.TTTS CS
         Ank    2 GnTPLHlAatngkkriiklLL.hGAn 26  
                  G T+L  Aa  g+ +i+ +LL +GA 
  EEA22937.1 1057 GLTALQTAAETGNINIAVELLrRGAH 1082
                  89*******889999******88986 PP

  == domain 14  score: 7.4 bits;  conditional E-value: 0.0021
                  TSBBHHHHHHHHTTHHHHHHHH.T CS
         Ank    1 dGnTPLHlAatngkkriiklLL.h 23  
                  +G+T+   Aa++g +++++lLL h
  EEA22937.1 1091 YGRTAITAAACYGREDMLQLLLdH 1114
                  69*****9999***********76 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0       1.2   3.5e+03       3      39 ..     374     408 ..     373     412 .. 0.75
   2 !    5.7   0.1    0.0065        19       8      40 ..     463     492 ..     458     500 .. 0.82
   3 !   14.0   0.0   1.5e-05     0.046       1      44 [.     487     530 ..     487     531 .. 0.92
   4 ?    4.9   0.1     0.011        34      16      44 ..     562     589 ..     549     590 .. 0.82
   5 !   13.4   0.0   2.5e-05     0.075       8      44 ..     663     695 ..     651     699 .. 0.81
   6 !   11.0   0.1   0.00014      0.43      15      54 ..     701     742 ..     695     744 .. 0.90
   7 !   14.2   0.1   1.4e-05     0.042       8      43 ..     729     764 ..     724     766 .. 0.81
   8 ?    2.8   0.0     0.053   1.6e+02      14      39 ..     770     795 ..     768     801 .. 0.87
   9 !   14.1   0.0   1.4e-05     0.043       1      47 [.     820     865 ..     820     871 .. 0.85
  10 ?    1.1   0.0      0.18   5.5e+02      18      36 ..     873     891 ..     865     899 .. 0.85
  11 !   11.1   0.0   0.00013       0.4       1      46 [.     975    1018 ..     975    1029 .. 0.82
  12 !   13.5   0.1   2.3e-05     0.068       1      41 [.    1041    1082 ..    1041    1088 .. 0.92
  13 ?   -0.0   0.0      0.41   1.2e+03      15      37 ..    1091    1113 ..    1084    1118 .. 0.78

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 1.2
       Ank_5   3 ehg.padvnrldgggntpLhvAakygaadvvrlLlarg 39 
                 +++ p d  +l++    ++ +A+ ++ +++++lL++ g
  EEA22937.1 374 DNDlPLDAEYLQE---YCITIAVQRQDQRMLQLLCEAG 408
                 6666666666665...7888999999999999999655 PP

  == domain 2  score: 5.7 bits;  conditional E-value: 0.0065
       Ank_5   8 dvnrldgggntpLhvAakygaadvvrlLlarga 40 
                  vn ++g    pL++Aa+ g++  v +Ll+ g+
  EEA22937.1 463 LVNVERG---FPLINAAELGNLAAVDMLLKAGS 492
                 5666666...8******************7665 PP

  == domain 3  score: 14.0 bits;  conditional E-value: 1.5e-05
       Ank_5   1 Llehg.padvnrldgggntpLhvAakygaadvvrlLlargadlnl 44 
                 Ll++g  ++   +d +g tpL  A++++ a +v++L+a gad n+
  EEA22937.1 487 LLKAGsRVNSYVRDYFG-TPLQAAVYANQAKMVEFLIAKGADVNA 530
                 78888888899999999.************************996 PP

  == domain 4  score: 4.9 bits;  conditional E-value: 0.011
       Ank_5  16 gntpLhvAakygaadvvrlLlargadlnl 44 
                 + tp+ +A++ ++ ++v+lLla+ga  +l
  EEA22937.1 562 K-TPIQIACEMNNMSLVELLLANGALVDL 589
                 4.9*********************98765 PP

  == domain 5  score: 13.4 bits;  conditional E-value: 2.5e-05
       Ank_5   8 dvnrldgggntpLhvAakygaadvvrlLlargadlnl 44 
                  +n+ d    tpL +Aa+ +++++v +L+++ga+ n+
  EEA22937.1 663 IPNWGD----TPLQMAARLNYPEIVSILMENGANVNA 695
                 355555....************************996 PP

  == domain 6  score: 11.0 bits;  conditional E-value: 0.00014
       Ank_5  15 ggntpLhvAakygaadvvrlLl..argadlnltdsrGltald 54 
                 +g t+L  Aa+ g+ ++v+lLl  +  +++ +  +rGltal+
  EEA22937.1 701 NGRTALQAAAESGNIEMVQLLLfsNADVNAPAGYERGLTALQ 742
                 455*************************************98 PP

  == domain 7  score: 14.2 bits;  conditional E-value: 1.4e-05
       Ank_5   8 dvnrldgggntpLhvAakygaadvvrlLlargadln 43 
                 +  +  ++g t+L  A+k+g++dv++lLl+ +ad+ 
  EEA22937.1 729 NAPAGYERGLTALQAAIKNGHFDVAELLLKSNADIH 764
                 4455567788*******************8888875 PP

  == domain 8  score: 2.8 bits;  conditional E-value: 0.053
       Ank_5  14 gggntpLhvAakygaadvvrlLlarg 39 
                 ++g +++  Aa++ +++++++L ++g
  EEA22937.1 770 RYGLSAIAAAASGKNLSMLEFLTKNG 795
                 689999***************98776 PP

  == domain 9  score: 14.1 bits;  conditional E-value: 1.4e-05
       Ank_5   1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltds 47 
                 Ll+hg  dvn  + +  +pL +++ ++++ ++++Ll+ ga+l+l  +
  EEA22937.1 820 LLQHG-SDVNSVCDDYISPLAWSITKQNLAMMKFLLESGANLKLPMK 865
                 89***.66666666655*******************99999998766 PP

  == domain 10  score: 1.1 bits;  conditional E-value: 0.18
       Ank_5  18 tpLhvAakygaadvvrlLl 36 
                  +L++A+++++++ ++++l
  EEA22937.1 873 DALCFAIEQRCPREIIFFL 891
                 79***************99 PP

  == domain 11  score: 11.1 bits;  conditional E-value: 0.00013
       Ank_5    1 LlehgpadvnrldgggntpLhvAakygaadvvrlLlargadlnltd 46  
                  Lle g advn ++ g  t+L  A+++g   ++++Ll++ga + +  
  EEA22937.1  975 LLEMG-ADVNMYEDGP-TALQSAIHAGQIGLAKYLLDEGAEIQVPA 1018
                  89999.*****98766.*******************9988877655 PP

  == domain 12  score: 13.5 bits;  conditional E-value: 2.3e-05
       Ank_5    1 Llehg.padvnrldgggntpLhvAakygaadvvrlLlargad 41  
                  Lle+g +++  +  +gg t+L +Aa+ g+ +++ +Ll rga+
  EEA22937.1 1041 LLERGaDVNASAAPNGGLTALQTAAETGNINIAVELLRRGAH 1082
                  899**999999999***********************88776 PP

  == domain 13  score: -0.0 bits;  conditional E-value: 0.41
       Ank_5   15 ggntpLhvAakygaadvvrlLla 37  
                  +g t++  Aa yg+ d+++lLl+
  EEA22937.1 1091 YGRTAITAAACYGREDMLQLLLD 1113
                  55566666666**********95 PP

>> Clr5  Clr5 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.2   0.3   9.9e-19     3e-15       3      54 .]      11      62 ..       9      62 .. 0.96

  Alignments for each domain:
  == domain 1  score: 56.2 bits;  conditional E-value: 9.9e-19
        Clr5  3 edWeahkatIrrLYleenrsLkdvmeiMeeehgFkatkrqyktrfkkWgfrk 54
                  W+ +k++I+ LY   + +L++vm+ M+e++gF++tk+qy t+ k+Wg++k
  EEA22937.1 11 SVWDGYKEEITALYTAPHGTLEKVMDAMKERYGFQPTKSQYATKWKQWGLQK 62
                56************************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1165 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       464  (0.0258799); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.96u 0.35s 00:00:01.31 Elapsed: 00:00:00.55
# Mc/sec: 6405.57
//
Query:       EEA22938.1  [L=309]
Description: WW domain protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.8e-10   40.7   0.5    4.3e-10   39.5   0.5    1.7  1  WW        WW domain
    4.7e-05   23.6  26.3    4.7e-05   23.6  26.3    2.8  2  DUF2076   Uncharacterized protein conserved in bacteria (DUF2


Domain annotation for each model (and alignments):
>> WW  WW domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   39.5   0.5   4.8e-14   4.3e-10       1      31 []      14      44 ..      14      44 .. 0.97

  Alignments for each domain:
  == domain 1  score: 39.5 bits;  conditional E-value: 4.8e-14
                X-TTEEEEE-TTTT-EEEEETTT--EESS-- CS
          WW  1 LPpGWeeqwdpdsGrvYYyNheTgetqWekP 31
                +PpGW++q+d++++ ++++N +Tg++qW+ P
  EEA22938.1 14 VPPGWKAQFDDRYKSWFFVNLKTGVSQWTVP 44
                6***************************988 PP

>> DUF2076  Uncharacterized protein conserved in bacteria (DUF2076)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   4.8      0.12   1.1e+03     193     250 ..      78     138 ..      62     146 .. 0.63
   2 !   23.6  26.3   5.3e-09   4.7e-05      81     191 ..     158     287 ..     148     303 .. 0.62

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.12
     DUF2076 193 sqsaeeeeiinnyy...ssssladdaedadnasadsfadsdsssdnnadaasdddsdddss 250
                 ++++ ++   nn+y   ++ s +++++d+ +  a+ +a++d+ +  n d  +++  +++ s
  EEA22938.1  78 EEKKSSHLASNNPYstgTGASGHQNMDDDAKLAAQLQAEEDARAAGNRDRGENSGYYNNAS 138
                 4444455555666677766666666666666666667777777777777777777777766 PP

  == domain 2  score: 23.6 bits;  conditional E-value: 5.3e-09
     DUF2076  81 aqaqpssggFLsglFGggkke........................rpqpspqarpaapagqalgqeeqyaaqpgyaqqqaqpqygqpaaapqpggGggF 155
                 +q+ +   gFL+ l+G+ +++                        +p+p+pq    +p +  ++ ++q + +p+   q ++pq+g+++++p  ++ gg 
  EEA22938.1 158 QQQSSGNRGFLGRLLGKSPNKqynavpppqgqyppqhggyggygsPPPPPPQGYGGYPPQGGYYPPQQGYYPPQ---QGYYPQQGYAQPPP--KKSGGG 251
                 44555578***********9988876655555555555555544433333333444444333333322222221...34455555444443..444467 PP

     DUF2076 156 LggAlqtAAGVaGGvllangleslfsgksgeegaas 191
                 Lg+A ++A G+ GG l++  +++ ++++ ++e +++
  EEA22938.1 252 LGTAGAAALGIGGGLLAGALITDAIQDHDQAEYQQG 287
                 ***************************875554333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       529  (0.0295053); expected 358.6 (0.02)
Passed bias filter:                      321  (0.017904); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.37s 00:00:00.99 Elapsed: 00:00:00.54
# Mc/sec: 1714.56
//
Query:       EEA22939.1  [L=1082]
Description: WD repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      5e-12   46.1  15.3     0.0042   17.9   0.1    7.4  7  WD40      WD domain, G-beta repeat


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.9   0.0    0.0007        13       2      28 ..     449     476 ..     448     484 .. 0.85
   2 !   17.9   0.1   2.3e-07    0.0042      10      38 .]     519     551 ..     513     551 .. 0.76
   3 !    5.7   0.1    0.0017        31      23      37 ..     581     594 ..     559     595 .. 0.75
   4 ?    2.2   0.0     0.022   3.9e+02      12      29 ..     683     700 ..     676     710 .. 0.85
   5 !    9.5   0.2   0.00011       1.9      12      38 .]     739     766 ..     727     766 .. 0.83
   6 !    7.5   0.1   0.00046       8.2       4      38 .]     774     824 ..     771     824 .. 0.71
   7 ?   -0.2   0.0      0.12   2.2e+03      10      29 ..     833     860 ..     828     867 .. 0.78

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.0007
                 EEEEEEESS.SSEEEEEEETTSSEEEEE CS
        WD40   2 qclrtltGH.ssvtslafspdgawlasG 28 
                 q+ +t++G  ++v  la+spdg  +a G
  EEA22939.1 449 QKSHTWKGAsNDVLNLAWSPDGFRFAVG 476
                 67899****999*********9777766 PP

  == domain 2  score: 17.9 bits;  conditional E-value: 2.3e-07
                 S.SS.....EEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40  10 H.ss.....vtslafspdgawlasGsdDgtvriWd 38 
                 H +s     vt++++ +d  +  ++s+D+tv+iWd
  EEA22939.1 519 HnNShlymsVTAVQWFDDTLY--TSSYDKTVKIWD 551
                 543346666****77777766..7888*******9 PP

  == domain 3  score: 5.7 bits;  conditional E-value: 0.0017
                 SEEEEEETTSEEEEE CS
        WD40  23 awlasGsdDgtvriW 37 
                 ++la+G+ D t+++W
  EEA22939.1 581 TLLATGT-DSTLHLW 594
                 3489999.******* PP

  == domain 4  score: 2.2 bits;  conditional E-value: 0.022
                 SEEEEEEETTSSEEEEEE CS
        WD40  12 svtslafspdgawlasGs 29 
                 ++ +++ +p  +w+a+Gs
  EEA22939.1 683 NIFDVKSHPFLPWFATGS 700
                 48899***********97 PP

  == domain 5  score: 9.5 bits;  conditional E-value: 0.00011
                 SEEEEEEETTSSEEEEE.ETTSEEEEEE CS
        WD40  12 svtslafspdgawlasG.sdDgtvriWd 38 
                 ++++++f+p  ++++s+ + Dg  ++Wd
  EEA22939.1 739 DINDVSFCPMDRFHISAsCTDGITYVWD 766
                 49***********9765235*******9 PP

  == domain 6  score: 7.5 bits;  conditional E-value: 0.00046
                 EEEEESS.SSEEEEE................EETTSSEEEEEETTSEEEEEE CS
        WD40   4 lrtltGH.ssvtsla................fspdgawlasGsdDgtvriWd 38 
                 l++l  H + ++ l+                + + ++ +++G+ Dg +r Wd
  EEA22939.1 774 LHKL-CHgDAINQLDeeltreqadvgvrvalWGKGSDEFITGGSDGVLRSWD 824
                 5555.574447777777777777777777787777777889977*******9 PP

  == domain 7  score: -0.2 bits;  conditional E-value: 0.12
                 SSSEEEEE..........EETTSSEEEEEE CS
        WD40  10 Hssvtsla..........fspdgawlasGs 29 
                 H  v+++a          fspd++ l+ G+
  EEA22939.1 833 H--VRDIAviedeimsgaFSPDKSTLLIGD 860
                 4..677777777777888******998774 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1082 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       756  (0.0421663); expected 358.6 (0.02)
Passed bias filter:                      517  (0.028836); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.82u 0.30s 00:00:01.11 Elapsed: 00:00:00.48
# Mc/sec: 6812.41
//
Query:       EEA22940.1  [L=324]
Description: peroxisomal membrane protein Pmp47, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
      2e-53  178.3   1.4    1.8e-17   63.0   0.1    3.1  3  Mito_carr  Mitochondrial carrier protein
  ------ inclusion threshold ------
      0.035   14.0   0.1       0.11   12.4   0.1    1.9  1  UcrQ       UcrQ family
      0.037   14.3   0.0        3.2    8.0   0.0    3.2  3  HMD        H2-forming N5,N10-methylene-tetrahydromethanopteri
       0.11   12.8   1.3          3    8.2   0.1    2.8  2  TadE       TadE-like protein
       0.12   12.5   0.0        3.8    7.7   0.0    2.3  2  PrcB_C     PrcB C-terminal
        0.3   11.2   5.9         12    6.1   0.0    3.4  3  VIGSSK     Helicase-associated putative binding domain, C-ter


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   63.0   0.1   5.9e-21   1.8e-17       4      95 ..      23     110 ..      20     112 .. 0.94
   2 !   58.4   0.0   1.7e-19     5e-16       2      95 ..     121     222 ..     120     224 .. 0.84
   3 !   54.9   0.1   2.1e-18   6.3e-15       8      93 ..     231     313 ..     225     317 .. 0.92

  Alignments for each domain:
  == domain 1  score: 63.0 bits;  conditional E-value: 5.9e-21
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHCT CS
   Mito_carr   4 svlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlllk 95 
                   +++ laG+ +g+++ ++t+Pl ++ tr q+++k++++s    +ld++++i++ eG++gly+Gl+ +l++++ +++++   ye ++  + k
  EEA22940.1  23 DNIAHALAGAGGGILSMVLTYPLITLSTRAQVESKRAQSS----TLDAVRHIIQREGISGLYSGLNSALFGISMTNFVYYYWYEWTRAAFEK 110
                 567899******************************9986....8******************************************99977 PP

  == domain 2  score: 58.4 bits;  conditional E-value: 1.7e-19
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSS.........HHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   2 elsvlkellaGglagavatlvttPldvvKtrlqtqkksskksksaa.........ildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkr 91 
                 +l++++ ++aG++ag++++l+t+P++v+ tr+ + ++++ +++  +         ++++l  ++k+eG ++l+ G+lp+l+ v+ +  l+ +++e+lk+
  EEA22940.1 121 KLTTIEAIIAGAIAGSATVLLTNPIWVINTRMTARRNEAGEQGLPGaekpkqsksTIQTLLDLLKNEGPSALFAGVLPALVLVI-NPILQYTIFEQLKN 218
                 5678899***************************555544433333444445555***************************99.************** PP

                 HHCT CS
   Mito_carr  92 lllk 95 
                 +l +
  EEA22940.1 219 VLER 222
                 9976 PP

  == domain 3  score: 54.9 bits;  conditional E-value: 2.1e-18
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   8 ellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrll 93 
                  +  G++++++at++t+P  +vK r+ +++k+   ++   +   lkki+ eeG +gly+G++p+++++a+++a  f++ ++l +++
  EEA22940.1 231 AFYLGAIGKILATSITYPYITVKSRMHVASKNDPRQT---LNGSLKKIINEEGCAGLYKGIIPKVTQSAITAAFLFAFKDVLYDVM 313
                 5789****************************99877...8899**********************************99987765 PP

>> UcrQ  UcrQ family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   3.7e-05      0.11      43      76 ..      85     118 ..      66     120 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 3.7e-05
                 TTHHHHHHHHHHHHHHHHHHHHHHHHHTSGGGHH CS
        UcrQ  43 sqvlyvlppfiiayliykwakeeneylnrKagrd 76 
                 s ++ + +  +++y++y+w+++ +e++  Kagr+
  EEA22940.1  85 SALFGISMTNFVYYYWYEWTRAAFEKAAEKAGRA 118
                 566667777789********************96 PP

>> HMD  H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   0.0    0.0011       3.2      45      77 ..      61      93 ..      27     110 .. 0.78
   2 ?    0.7   0.0       0.2     6e+02      42      66 ..     171     195 ..     166     222 .. 0.79
   3 ?    0.6   0.0      0.23   6.7e+02      51      76 ..     272     297 ..     258     315 .. 0.72

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0011
                HHHHHHHHHHHHHHHHHHHHHCC-HHHHHHCHH CS
         HMD 45 lesLqtiaslveksGieglekalnpelllksak 77
                  +L+ + ++++++Gi gl   ln +l+  s  
  EEA22940.1 61 SSTLDAVRHIIQREGISGLYSGLNSALFGISMT 93
                468*********************999866655 PP

  == domain 2  score: 0.7 bits;  conditional E-value: 0.2
                 HHHHHHHHHHHHHHHHHHHHHHHHC CS
         HMD  42 kqilesLqtiaslveksGiegleka 66 
                 kq + ++qt+ +l++++G   l   
  EEA22940.1 171 KQSKSTIQTLLDLLKNEGPSALFAG 195
                 577899**********997777655 PP

  == domain 3  score: 0.6 bits;  conditional E-value: 0.23
                 HHHHHHHHHHHHHHHCC-HHHHHHCH CS
         HMD  51 iaslveksGieglekalnpelllksa 76 
                 ++++++++G +gl k + p++  ++ 
  EEA22940.1 272 LKKIINEEGCAGLYKGIIPKVTQSAI 297
                 66788899999999888888765544 PP

>> TadE  TadE-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.1     0.066     2e+02      22      43 .]      96     117 ..      87     117 .. 0.87
   2 ?    8.2   0.1     0.001         3       7      35 ..     193     221 ..     192     222 .. 0.95

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.066
        TadE  22 iefgrylyarqtlnnAAreaAR 43 
                 +++ +y ++r + + AA  a R
  EEA22940.1  96 VYYYWYEWTRAAFEKAAEKAGR 117
                 7899999**********99977 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.001
        TadE   7 FALvlPlllllllgiiefgrylyarqtln 35 
                 FA vlP l+l++  i+++ ++ +++++l+
  EEA22940.1 193 FAGVLPALVLVINPILQYTIFEQLKNVLE 221
                 999**********************9986 PP

>> PrcB_C  PrcB C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0     0.059   1.8e+02      41      57 ..      34      50 ..      24      51 .. 0.83
   2 ?    7.7   0.0    0.0013       3.8      41      56 ..     238     253 ..     225     255 .. 0.86

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.059
      PrcB_C 41 geevtqaltyPyvvvki 57
                g + +++ltyP + +++
  EEA22940.1 34 GGILSMVLTYPLITLST 50
                567899******99876 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.0013
      PrcB_C  41 geevtqaltyPyvvvk 56 
                 g + +  +tyPy+ vk
  EEA22940.1 238 GKILATSITYPYITVK 253
                 77888999******98 PP

>> VIGSSK  Helicase-associated putative binding domain, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.5   0.9     0.052   1.5e+02      13      37 ..       9      33 ..       2      35 .. 0.74
   2 ?    6.1   0.0    0.0042        12      15      51 ..      53      91 ..      45      94 .. 0.81
   3 ?    3.1   0.1     0.036   1.1e+02      13      36 ..     109     132 ..     102     135 .. 0.78

  Alignments for each domain:
  == domain 1  score: 2.5 bits;  conditional E-value: 0.052
      VIGSSK 13 ekkkeakkstkkksDaiqAILasaG 37
                +kk  a+++++++sD i+  La+aG
  EEA22940.1  9 QKKAVAASAAAQQSDNIAHALAGAG 33
                33333344599*************8 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.0042
      VIGSSK 15 kkeakkstkkksDaiqAILasaGVe..YTHenseViGsS 51
                + e+k++++   Da++ I ++ G+   Y+  ns++ G S
  EEA22940.1 53 QVESKRAQSSTLDAVRHIIQREGISglYSGLNSALFGIS 91
                44556668999*************777999999999977 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.036
      VIGSSK  13 ekkkeakkstkkksDaiqAILasa 36 
                 ek+ e++ +++kk   i+AI a+a
  EEA22940.1 109 EKAAEKAGRASKKLTTIEAIIAGA 132
                 45555566699**********998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (324 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       795  (0.0443416); expected 358.6 (0.02)
Passed bias filter:                      576  (0.0321267); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.48u 0.26s 00:00:00.74 Elapsed: 00:00:00.40
# Mc/sec: 2432.22
//
Query:       EEA22941.1  [L=1176]
Description: aminopeptidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.4e-89  300.8   1.0    2.2e-89  300.1   1.0    1.3  1  ERAP1_C         ERAP1-like C-terminal domain
    2.2e-83  279.1   1.4    2.2e-83  279.1   1.4    1.8  2  Peptidase_M1    Peptidase family M1 domain
    3.8e-64  215.2   0.5    7.4e-64  214.2   0.5    1.5  1  Ras             Ras family
    1.9e-38  132.5   0.0    1.7e-37  129.4   0.0    2.2  2  Peptidase_M1_N  Peptidase M1 N-terminal domain
    1.7e-34  118.6   0.1    3.3e-34  117.7   0.1    1.5  1  Roc             Ras of Complex, Roc, domain of DAPkinase
    4.9e-15   55.4   0.1    1.1e-14   54.3   0.1    1.5  1  Arf             ADP-ribosylation factor family
      0.001   19.1   0.0     0.0021   18.1   0.0    1.6  1  MMR_HSR1        50S ribosome-binding GTPase
     0.0036   17.2   0.3        1.3    8.9   0.0    2.5  2  RsgA_GTPase     RsgA GTPase
     0.0039   16.6   0.1     0.0071   15.7   0.1    1.4  1  Gtr1_RagA       Gtr1/RagA G protein conserved region
     0.0051   16.4   0.1      0.011   15.3   0.1    1.5  1  GTP_EFTU        Elongation factor Tu GTP binding domain
  ------ inclusion threshold ------
      0.017   14.6   0.0      0.034   13.6   0.0    1.4  1  SRPRB           Signal recognition particle receptor beta sub
       0.04   14.3   0.1        5.1    7.5   0.0    2.9  2  AAA             ATPase family associated with various cellula
       0.14   12.5   0.0       0.35   11.2   0.0    1.7  1  AAA_16          AAA ATPase domain


Domain annotation for each model (and alignments):
>> ERAP1_C  ERAP1-like C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  300.1   1.0   1.6e-92   2.2e-89       1     314 [.     625     940 ..     625     941 .. 0.96

  Alignments for each domain:
  == domain 1  score: 300.1 bits;  conditional E-value: 1.6e-92
                 -EEESGGG-SSSEEEE-HHHHHHHHHHHHGGGS-HHHHHHHHHHHHHHHHTTSS-HHHHHHGGG.GGGG--SHHHHHHHHHHHHHHHHHHT.TSTTHHH CS
     ERAP1_C   1 lvllNdddtGyyrVnYdeeslaalleqllskklspldRaglisdafalaragelsaadlldlllgylanEtdylvwsqalsqlatlkslls.adplyaa 98 
                 ++++N d++G+yr+nY++e+la+l++  l+  ls++d++gli+da+ala +ge ++ +ll+l++g+ a+E++ylvw+q+ s+la+l++++s +++++aa
  EEA22941.1 625 FYKINKDQSGFYRTNYPPERLAKLGK-SLHL-LSTEDKIGLIGDAAALAVSGEGTTPALLALIEGF-AQENNYLVWQQISSSLASLRTTFSsNEAAAAA 720
                 79************************.5666.**********************************.7**********************94455999* PP

                 HHHHHHHHHHHHHHHHHHT...TTS-HHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHCSTT.-.S-HHHHHHHHHHHHHHS-HHHHHHHHHHHHC-S CS
     ERAP1_C  99 lkaflrklleplaeklgwe..pgeshldaqlrslllsaacaagdpevveearklfkawlegdd.l.ippdlrwavycalaanggeaewdallerykdts 193
                 lk+f ++l++p+aek+gwe  ++e++l+ qlr+ll+++a+ ag++  v+ea+++f+ w++g+d + i+++lr+a+++  +a g++ae++ + +++ +t+
  EEA22941.1 721 LKKFKLNLVTPAAEKVGWEfrSDEDYLTGQLRKLLIAMAGEAGHEGIVAEAKRRFQLWASGEDpNaIHSNLRSAIFSLNIAEGDRAEFERVKNEFLQTD 819
                 ******************66477************************************9988856*****************************8888 PP

                 SHHHHHHHHHHHCC-S-HHHHHHHHHHCTTT..S-GGGHHHHHHHH.HSTTHHHHHHHHHHHCHCCHHHHTSSTSCH.HHHHHHHHTT--SHHHHHHHH CS
     ERAP1_C 194 apsekeaalralaatpdpellerllnfvlesdevrnqdlrallaglannpegrellwefvkenwdalakrwsggeil.drivkgllpgftseeelaeie 291
                 + ++ke++l++l+ t++pel++++l+f++ sd+v+ qd+++ +a+la np gr +lw+++k+n+ a+++r+s ++i+ dr+v+  l+ f++ + +++i 
  EEA22941.1 820 SVDGKEICLSSLGRTRNPELIQQYLDFIF-SDKVSIQDMHTGAASLAVNPIGRYALWQYIKTNFTAVSARLSANNIVyDRFVRLGLSKFSDVAIADDIA 917
                 88**************************9.99**************99***********************9888666********************* PP

                 HHHCHTT--GGGHHHHHHHHHHH CS
     ERAP1_C 292 affadkdtpglrrtlkqaletvr 314
                 +ff+dkdt +++rtl    +++r
  EEA22941.1 918 KFFEDKDTGAFERTLVILSDSIR 940
                 ***************99988887 PP

>> Peptidase_M1  Peptidase family M1 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  279.1   1.4   1.6e-86   2.2e-83       1     218 []     334     551 ..     334     551 .. 1.00
   2 ?   -2.9   0.0       2.9   4.1e+03      94     124 ..     684     715 ..     682     727 .. 0.71

  Alignments for each domain:
  == domain 1  score: 279.1 bits;  conditional E-value: 1.6e-86
                   HHHHHHHHHHHHHHHHHTS--SSSEEEEEEESSTTSSEEEETTEEEEEGGGC-SSTTTS-HHHHHHHHHHHHHHHHHHHBTTTEEESSGGGGHHHHH CS
  Peptidase_M1   1 yalevtkkllefleeyfkvpYplpkldlvalpdfsagAMEnwglityreelllvdpenssesdkrsvaeviaHElaHqWfGnlVtmkwWddlwLnEG 97 
                   yale ++k++++++e f+++Yplpk+dl++++ f+agAMEnwgl+tyr +++l+d+++s++++k+++a v+aHElaHqWfGnlVtm+wW++lwLnEG
    EEA22941.1 334 YALECAHKTIDYFSELFGIEYPLPKSDLLCVHAFAAGAMENWGLVTYRTTAVLFDEGKSDSRYKNRIAYVVAHELAHQWFGNLVTMDWWSELWLNEG 430
                   89*********************************************************************************************** PP

                   HHHHHHHHHHHHHSCCCHCHHHHHHHCHHHHHHHHTSTTHHHSSGG-GSHHHHHHTSSHHHHHHHHHHHHHHHHHCTHHHHHHHHHHHHHHCTTEEE CS
  Peptidase_M1  98 fatyleylildklepewevseqllleeveealsedaldeshpitqevekpseidevFdsiaYeKGasllrmlekllgeevFqkglksYlkefkykna 194
                   fat++ +l +d+++p+w+v++q+++e v++a + d+l+ shpi++ v+++ e+d++Fd i+Y KG+s++rml++ lg++vF kg++ Ylk+++y+na
    EEA22941.1 431 FATWVGWLAVDHFHPDWNVWSQFVAEGVQQACQLDSLRASHPIEVPVKNALEVDQIFDHISYLKGSSVIRMLSSHLGQDVFIKGVSDYLKKHAYGNA 527
                   ************************************************************************************************* PP

                   -HHHHHHHHHHCCCSCHHTHHHHH CS
  Peptidase_M1 195 etedlwdaleealnkdisevmdtw 218
                   +t+dlw+al++a+n+d++++md w
    EEA22941.1 528 TTNDLWSALSKASNLDVNALMDPW 551
                   ***********************9 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 2.9
                   HHHHHHHHHHHHHHHHHSCCCH.CHHHHHHHC CS
  Peptidase_M1  94 LnEGfatyleylildklepewe.vseqlllee 124
                   L EGfa+  +yl+ ++++++   +++++  +e
    EEA22941.1 684 LIEGFAQENNYLVWQQISSSLAsLRTTFSSNE 715
                   779****9999999999996663555554443 PP

>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  214.2   0.5   5.3e-67   7.4e-64       1     161 [.     985    1145 ..     985    1146 .. 0.99

  Alignments for each domain:
  == domain 1  score: 214.2 bits;  conditional E-value: 5.3e-67
                  EEEEEESTTSSHHHHHHHHHHSSCSSSCTTTSSEEEEEEEEEETTEEEEEEEEEETTSGGGHHHHHHHHTTESEEEEEEETTBHHHHHTHHHHHHHH CS
         Ras    1 KlvlvGdsavGKtslllrfvkdkFkeeyesTigvdfytkeievdgkevkleiwDTAGqeefkslrelyyrdaegillvyditsresfenvkkwveei 97  
                  Kl+l+Gds+vGK++lllrf++d+++e+y+sTigvdf++++ie+dgk+vkl+iwDTAGqe+f++++++yyr+a+gi +vyd+t+ +sf+nvk+w++ei
  EEA22941.1  985 KLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTVKLQIWDTAGQERFRTITSSYYRGAHGICVVYDVTDMDSFNNVKQWLQEI 1081
                  89*********************************************************************************************** PP

                  HHHSTTTSEEEEEEETTTGGGG-SS-HHHHHHHHHHHTSEEEEEBTTTTCTHHHHHHHHHHHHH CS
         Ras   98 krvaeenvpivLvGnKvDleekravsteegeelakelglkfletSAktnenveeafeellreil 161 
                   r+a+e v+ +LvGnK+D+e+k++v+++ ++e+a++lg++fletSAk++ nve+af +++r+i+
  EEA22941.1 1082 DRYATEGVNKLLVGNKSDMEDKKVVEYTVAKEFADSLGIPFLETSAKSASNVEQAFLTMARQIK 1145
                  *************************************************************996 PP

>> Peptidase_M1_N  Peptidase M1 N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  129.4   0.0   1.2e-40   1.7e-37       2     186 .]     100     294 ..      99     294 .. 0.86
   2 ?    0.2   0.0      0.54   7.5e+02      95     109 ..     627     641 ..     606     648 .. 0.86

  Alignments for each domain:
  == domain 1  score: 129.4 bits;  conditional E-value: 1.2e-40
                     EEEEEEEEEEETT...TTEEEEEEEEEEEESS-ECEEEEEESSEEEECEEEEECTTCTCEEEEEEEECTTTTCEEEEECCEEETTCEEEEEEEEE CS
  Peptidase_M1_N   2 pehYdldlkidlk...ektfkGsvtitlqlkeatseivldakdlkiksvslsaevksesvkidfkieqkdeelltiklkeslqqtskytLeieye 93 
                     p+ Yd++l  +l+   + +++G+v+i+++++++t+ei+l+ k++ ++++++   ++s+svk+    ++k  e +t+ ++++   ++ + L+ie +
      EEA22941.1 100 PKRYDISLY-NLElggSWSYNGTVKIDTTVSKPTKEIILNVKEVSVEKAEVQ--AGSTSVKAVGISYDKVSERVTLAFDKEIP-SGDALLTIECT 190
                     677777774.4444677889**************************877776..8888889999999999999***9999766.9********** PP

                     EE-BSSSSEEE..........EEEEEETSCEEEEEEEE-TTTTGGGTS-B--STTSEBEEEEEEEEETTSEEEESSECCCEEEET.TCEEEEEEE CS
  Peptidase_M1_N  94 gelndklaGly..........kstYtdkgekkvvvvTqfeatdARsafPCfDePsvKAtftisikapkeetalSnmpeeesekle.ngqkiteFe 177
                     + +n+ +aG+           +s  ++ ++  ++++Tqfea dAR+afPCfDeP+ KA+f+++i++pk+ +alSnmp++++ +   +g+ki+ Fe
      EEA22941.1 191 ATINEAMAGFSrckykapvtpSSATPELDGFHYMMSTQFEACDARRAFPCFDEPNLKAEFDFEIEVPKDLVALSNMPVKSERDGSkEGWKIVSFE 285
                     ***********5555555544333334556679*********************************************988776669******** PP

                     EEESBEGGG CS
  Peptidase_M1_N 178 qtpkmstYL 186
                     +tp mstYL
      EEA22941.1 286 RTPIMSTYL 294
                     ********9 PP

  == domain 2  score: 0.2 bits;  conditional E-value: 0.54
                     E-BSSSSEEEEEEEE CS
  Peptidase_M1_N  95 elndklaGlykstYt 109
                     ++n++  G+y+++Y+
      EEA22941.1 627 KINKDQSGFYRTNYP 641
                     68************7 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  117.7   0.1   2.4e-37   3.3e-34       1     120 []     985    1100 ..     985    1100 .. 0.91

  Alignments for each domain:
  == domain 1  score: 117.7 bits;  conditional E-value: 2.4e-37
                  EEEEESSTTSSHHHHHHCHCT-CCC-EEETTTTEEEEEEECGGSGGCTTBTTTTCEEEEEEEE-SGGCTTTT-HHHHCTSCEEEEEEE...GHHHHC CS
         Roc    1 KvvlvGdsgvGKtsllkrfvedkfsekekstigvdfltkevtkikgvendkkvkkvklniWDtaGqerfrslhplylreaalailvyd...srssen 94  
                  K++l+GdsgvGK++ll rf +d+++e++ stigvdf+ +++ +++g       k+vkl+iWDtaGqerfr+++++y+r+a+ +++vyd    +s++n
  EEA22941.1  985 KLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTI-ELDG-------KTVKLQIWDTAGQERFRTITSSYYRGAHGICVVYDvtdMDSFNN 1073
                  89**********************************98876.4444.......689*******************************965455789* PP

                  HHHHHHHHHHHCSSS.-EEEEEE-TTT CS
         Roc   95 lkeWlkelkkvagks.pvilvgnkiDl 120 
                  +k+Wl+e++++a++  + +lvgnk D+
  EEA22941.1 1074 VKQWLQEIDRYATEGvNKLLVGNKSDM 1100
                  ***********9986478*******96 PP

>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.3   0.1   7.6e-18   1.1e-14      15     131 ..     984    1104 ..     976    1144 .. 0.85

  Alignments for each domain:
  == domain 1  score: 54.3 bits;  conditional E-value: 7.6e-18
                  EEEEEEESTTSSHHHHHHHHHHSSCEE.CSSSSS..EEEEEEEE..TTEEEEEEEE-SSGGGGGGGGGGCTTESEEEEEEETT-CTTHHHHHHHHHH CS
         Arf   15 lrilllGLDnaGKtTilkklkleelvt.tvPTig..fnveelei..knlkftvwDvGGqeklRplWknYfektdavifvvDsadreRleeakeeLka 106 
                  +++ll+G  + GK+ +l ++ ++  ++  + Tig  f+++++e   k++k+++wD  Gqe+ R + ++Y++  +++  v D++d + +++ k+ L++
  EEA22941.1  984 FKLLLIGDSGVGKSCLLLRFADDTYTEsYISTIGvdFKIRTIELdgKTVKLQIWDTAGQERFRTITSSYYRGAHGICVVYDVTDMDSFNNVKQWLQE 1080
                  799*******************99877578898744678887776699************************************************9 PP

                  HCTSGCCTTSEEEEEEE-TTSTTSS CS
         Arf  107 lleeeelkevallvlaNKqDlpeal 131 
                  + ++   + v  l+++NK D+++  
  EEA22941.1 1081 I-DRYATEGVNKLLVGNKSDMEDKK 1104
                  7.6778899***********98764 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   1.6e-06    0.0021       2     107 ..     986    1084 ..     985    1142 .. 0.73

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 1.6e-06
                  EEEEESTTSSHHHHHHHHHTSTEEESSSTTSSSSEEEEEEEETT..EEEEEEECGGCSSHHHHHHHHHHHHHHHHCTSEEEEEEETTTTCSHHHHHH CS
    MMR_HSR1    2 vaivGrpNvGKStLinaltgekaivsdkpgtTrdinegrvklkg..keielvDtpGliegaseekglgkaflaleeadlillvvdaseeklkpldee 96  
                   +++G + vGKS L+ +  +++   s +     d + ++++l+g   +++++Dt+G  e   + + ++ ++ +   a+ i++v d++ + ++   ++
  EEA22941.1  986 LLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGktVKLQIWDTAG-QE---RFRTITSSYYR--GAHGICVVYDVT-D-MDSF-NN 1073
                  579****************986655555555555555555544433679*******.54...23355666553..4899*****977.3.4444.55 PP

                  HHHHHHHTTSE CS
    MMR_HSR1   97 leelleeakkp 107 
                  ++++l+e ++ 
  EEA22941.1 1074 VKQWLQEIDRY 1084
                  66665553222 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.9   0.0   0.00093       1.3     103     122 ..     987    1006 ..     983    1058 .. 0.86
   2 !    5.6   0.1    0.0095        13      42     101 ..    1084    1144 ..    1059    1153 .. 0.80

  Alignments for each domain:
  == domain 1  score: 8.9 bits;  conditional E-value: 0.00093
                   EEECSTTSSHHHHHHHHCTT CS
  RsgA_GTPase  103 vlvGqSGvGKStLinallpe 122 
                   +l+G SGvGKS L+ +++ +
   EEA22941.1  987 LLIGDSGVGKSCLLLRFADD 1006
                   69***********9777665 PP

  == domain 2  score: 5.6 bits;  conditional E-value: 0.0095
                   HHHTT-EEEEEEE-GGG--HHH.HHHHHHHHHHHTTSEEEE--TTTHTTHHHHHHHCTTSE CS
  RsgA_GTPase   42 aeekgiepvivlnKiDlleeee.eleelkeelealgyevllvsaktkegleelkellkdkt 101 
                   + ++g++ ++v nK D+ +++  e++  ke   +lg+++l +sak+ +++e+    ++ ++
   EEA22941.1 1084 YATEGVNKLLVGNKSDMEDKKVvEYTVAKEFADSLGIPFLETSAKSASNVEQAFLTMARQI 1144
                   45789999*********9999878889999999************9999987665555555 PP

>> Gtr1_RagA  Gtr1/RagA G protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.1   5.2e-06    0.0071       1      66 [.     985    1050 ..     985    1105 .. 0.70

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 5.2e-06
   Gtr1_RagA    1 kvLLmGksgsGKtsmrsiiF.dnylardtlrlgatidveksevrflgnltlnlwDcgGqeafveeyl 66  
                  k+LL+G sg GK+++      d y+   + ++g+  +++  e+   + ++l++wD  Gqe+f + + 
  EEA22941.1  985 KLLLIGDSGVGKSCLLLRFAdDTYTESYISTIGVDFKIRTIEL-DGKTVKLQIWDTAGQERFRTITS 1050
                  89************98664414455555666666666666666.35678************987653 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.1   7.7e-06     0.011      56     183 ..    1020    1135 ..    1002    1148 .. 0.71

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 7.7e-06
                  SSCEEEEEETTCSSEEEEEEEESSSGGGHHHHHHHHHT-SEEEEEEETTTB.....STHHHHHHHHHHHHTTTEEEEEEESCGSTHHHHHHHHHHHH CS
    GTP_EFTU   56 iksaaisleketkkylinliDtPGHvdFskevirglrvlDgavlvvdaveG.....vepqteevlrlalkegvpiivfiNKmDrlkaelkeiveevk 147 
                   k+ +i+l+  +k+ ++++ Dt G + F   ++  +r ++g ++v d+++      v+ q  + +    +egv+  ++ NK D+ ++++ e   +v 
  EEA22941.1 1020 FKIRTIELD--GKTVKLQIWDTAGQERFRTITSSYYRGAHGICVVYDVTDMdsfnnVK-QWLQEIDRYATEGVNKLLVGNKSDMEDKKVVEY--TVA 1111
                  455566666..*************************************9764444244.444444555679999*********997765443..233 PP

                  HHHHHHHHHHHHHHHTTTTTEEEEEEBTTTTBTHHH CS
    GTP_EFTU  148 qklsrkeeklekygekgekevpvvfgSalkgegvkt 183 
                  +++           +++   +p++ +Sa+++ +v++
  EEA22941.1 1112 KEF-----------ADS-LGIPFLETSAKSASNVEQ 1135
                  334...........122.246666666666666665 PP

>> SRPRB  Signal recognition particle receptor beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.0   2.4e-05     0.034       6     124 ..     986    1100 ..     983    1114 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 2.4e-05
                  EEEE-STTSSHHHHHHHHHHSS---B---S.S-EEETTG.....GGTT-SEEEETT-GCCSHHHHHHHHHHGGEEEEEEEEETTS-HHHHHHHHHHH CS
       SRPRB    6 vllvGlsdsGKTslftrLttdsvkktvtSq.essaalkv..ksekgskltliDfPGheklrqklleklkaksslkglvfvvDStidpkevkevAEll 99  
                  +ll+G s  GK  l+ r   d+++++++S     +  ++   + k  kl++ D  G+e++r+  + +    + ++g+  v D t d    ++v  +l
  EEA22941.1  986 LLLIGDSGVGKSCLLLRFADDTYTESYISTiGVDFKIRTieLDGKTVKLQIWDTAGQERFRTITSSY---YRGAHGICVVYDVT-DMDSFNNVKQWL 1078
                  79***************************97667776663345677788899*********865554...77888888888766.556677777777 PP

                  HHHHHHHHHHTT---EEEEEE-TTS CS
       SRPRB  100 yeilliteklkdavdiliACnKqel 124 
                   ei    +   ++v+ l+  nK+++
  EEA22941.1 1079 QEIDRYAT---EGVNKLLVGNKSDM 1100
                  77755544...66666666777765 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   0.0    0.0037       5.1       1      89 [.     986    1092 ..     986    1106 .. 0.69
   2 ?    3.5   0.1     0.064        89      13      60 ..    1109    1158 ..    1109    1161 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0037
                  EEEESSTTSSHHHHHHHHHHHH.............THEEEEEETTTCS.SSSTTHHHHHHHHHHHHHHHTS.TSEEEE.EETGGGHHHHH..TTCCC CS
         AAA    1 vllyGppGtGKTllakavakel.............gvefleisgsell.skyvgesekkirelfkeakeka.kpsilf.iDEidalaksr..sgses 79  
                  +ll+G  G+GK+ l    a ++             +++ +e++g+++  + +  ++++++r + ++  + a + +++  + ++d++++ +   ++ +
  EEA22941.1  986 LLLIGDSGVGKSCLLLRFADDTytesyistigvdfKIRTIELDGKTVKlQIWDTAGQERFRTITSSYYRGAhGICVVYdVTDMDSFNNVKqwLQEID 1082
                  69*******************6444444444444468899999999996778889999999999998888855555544667777755554434444 PP

                  HHHHHHHHHH CS
         AAA   80 eeeervvnqL 89  
                  + +++ vn+L
  EEA22941.1 1083 RYATEGVNKL 1092
                  4444444444 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.064
                  HHHHHHHHHHTHEEEEEETTTCS..SSSTTHHHHHHHHHHHHHHHTSTSE CS
         AAA   13 llakavakelgvefleisgsell..skyvgesekkirelfkeakekakps 60  
                  ++ak  a +lg++fle+s+++    ++ +  ++++i+e + +a  ++kp+
  EEA22941.1 1109 TVAKEFADSLGIPFLETSAKSASnvEQAFLTMARQIKERMGTATVNNKPT 1158
                  6899***************9998445599999999999999888877665 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   0.00025      0.35      27     104 ..     986    1084 ..     985    1149 .. 0.65

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00025
      AAA_16   27 vllsGesGvGKsslvrellr.alekd...........ggiflrgkcdqlesaipysalaqalareellrqllde.................aesael 94  
                  +ll+G+sGvGKs l+ ++++  ++++           + i l gk+++l       ++++++ + e +r + +                  ++ +++
  EEA22941.1  986 LLLIGDSGVGKSCLLLRFADdTYTESyistigvdfkiRTIELDGKTVKL-------QIWDTAGQ-ERFRTITSSyyrgahgicvvydvtdmDSFNNV 1074
                  69*************7777625555555544444432222244444444.......56666644.66666655555555555555555555555566 PP

      AAA_16   95 eawrekleea 104 
                   +w +++++ 
  EEA22941.1 1075 KQWLQEIDRY 1084
                  6666666555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1176 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       568  (0.0316805); expected 358.6 (0.02)
Passed bias filter:                      513  (0.0286129); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              13  [number of targets reported over threshold]
# CPU time: 0.84u 0.32s 00:00:01.15 Elapsed: 00:00:00.48
# Mc/sec: 7367.10
//
Query:       EEA22942.1  [L=453]
Description: RNA polymerase TFIIH complex subunit Ssl1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.2e-75  250.9   0.0    1.1e-74  250.5   0.0    1.1  1  Ssl1      Ssl1-like
    7.4e-19   67.7   8.7    7.4e-19   67.7   8.7    2.4  2  C1_4      TFIIH C1-like domain
      2e-18   67.0   0.0    4.3e-18   65.9   0.0    1.5  1  VWA_2     von Willebrand factor type A domain
    4.1e-06   27.2   0.0    5.8e-06   26.7   0.0    1.3  1  VWA       von Willebrand factor type A domain


Domain annotation for each model (and alignments):
>> Ssl1  Ssl1-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  250.5   0.0   2.4e-78   1.1e-74       1     193 []      92     289 ..      92     289 .. 0.98

  Alignments for each domain:
  == domain 1  score: 250.5 bits;  conditional E-value: 2.4e-78
                 EEE-SGGGGSSSSSS-HHHHHHHHHHHHHHHHHHHSTT-EEEEEEEETTEEEEEEEEES-HHHHHHHHHHHTTS---S---HHHHHHHHHHHHSSS-TT CS
        Ssl1   1 vlDlsrameekdlkpsrlavviklleefveeffdqnPisqlgliavkdkkaekltelsGnprkhikaLkslreveakgepsLqnaLelalasLkkvpsh 99 
                 vlDls++m+ekd++p+r+ + +++++efv eff+qnPisqlg+i ++d+ a +++++sGnp +hi+a+++lr  ++kg psLqnaLe+a+  L + psh
  EEA22942.1  92 VLDLSQSMAEKDIRPTRYLLALRYAQEFVIEFFEQNPISQLGVIGMRDGLAVRISDMSGNPTDHITAIHALRPDDPKGLPSLQNALEMARGALFHTPSH 190
                 89************************************************************************************************* PP

                 SEEEEEEEE-SS----SS-HHHHHHHHHHTT-EEEEEEESS--HHHHHHHHHTTT....TEEEE-SHHHHHHHHHHHHS--------.----EEEEE-- CS
        Ssl1 100 asrevliifsslstcDPgdiyetidelkkekirvsvigLsaevavckelaketkg....tysvvldethlkelllehvsPppaaksk.keaslikmGfP 193
                 ++revli+f+sl+++DPgdi++t+++l  +kirv ++gL+a+va+c+el+ +t+g    +y+v+l+e+h++el+++ ++Pp+a + + ++ +l++mGfP
  EEA22942.1 191 GTREVLIVFGSLLSSDPGDIHQTLKSLIADKIRVGIVGLAAQVAICRELCAKTNGgddsVYGVALNEQHFRELMMDVTIPPAAYSYRkSSSALLMMGFP 289
                 ******************************************************77999************************99883567799****9 PP

>> C1_4  TFIIH C1-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   3.8       3.7   1.7e+04      26      36 ..     311     321 ..     295     322 .. 0.83
   2 !   67.7   8.7   1.7e-22   7.4e-19       1      55 []     366     428 ..     366     428 .. 0.84

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 3.7
        C1_4  26 yrCekCkndFC 36 
                 y C +C n+ C
  EEA22942.1 311 YLCSRCGNKVC 321
                 89999999988 PP

  == domain 2  score: 67.7 bits;  conditional E-value: 1.7e-22
        C1_4   1 eCygCqkkfpklakkkkdee........ltssryrCekCkndFCiDCDvFiHesLHnCpGCes 55 
                 +Cy+C  +fp++    +           ++ssry+C +C+n+FCiDCD+F He+ HnCpGC+s
  EEA22942.1 366 NCYACGIQFPTVPPADQWGAfenqakgmSVSSRYECSACHNHFCIDCDLFAHEIVHNCPGCQS 428
                 7********998765332224455677799*******************************96 PP

>> VWA_2  von Willebrand factor type A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.9   0.0   9.5e-22   4.3e-18       1     104 [.      89     199 ..      89     202 .. 0.92

  Alignments for each domain:
  == domain 1  score: 65.9 bits;  conditional E-value: 9.5e-22
       VWA_2   1 lvfvlDtSgSmrngdygpt....rleaakdaveallkslpgdrvglvtfsdg.pevlipltkdkakilnalrnleak..gggtnlaaaLqlarkalkkr 92 
                 l++vlD S+Sm+++d +pt     l +a+++v+++++++p +++g++ ++dg + ++++++ +++++ +a+++l+++  +g  +l++aL++ar al ++
  EEA22942.1  89 LILVLDLSQSMAEKDIRPTryllALRYAQEFVIEFFEQNPISQLGVIGMRDGlAVRISDMSGNPTDHITAIHALRPDdpKGLPSLQNALEMARGALFHT 187
                 689**************99666678999***********************73677789**************************************** PP

       VWA_2  93 rkgekrvivlit 104
                 +++ +r++++++
  EEA22942.1 188 PSHGTREVLIVF 199
                 *88888888776 PP

>> VWA  von Willebrand factor type A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.7   0.0   1.3e-09   5.8e-06       2     140 ..      89     232 ..      88     283 .. 0.85

  Alignments for each domain:
  == domain 1  score: 26.7 bits;  conditional E-value: 1.3e-09
                 EEEEEE-STTSCHHHHH.....HHHHHHHHHHHHHTBTTTTEEEEEEEESSSEEEE.EETTSHCHHHHHHHHHHTG.SGGGGSSC-HHHHHHHHHHHHH CS
         VWA   2 ivfvlDgSgsmgeenfe.....kvkefikklveklevgpegtrvglvqfssevkte.fslndysskeellsalnnl.kysgggttntgkalkyaleklf 93 
                 +++vlD S+sm e+++       ++++++++v ++  +++  ++g++ + +   +   +++   + ++ ++a+++l +  ++g  ++  al+ a+  lf
  EEA22942.1  89 LILVLDLSQSMAEKDIRptrylLALRYAQEFVIEFFEQNPISQLGVIGMRDGLAVRiSDMSG--NPTDHITAIHALrPDDPKGLPSLQNALEMARGALF 185
                 789********999999999999999999999999999999*********995444144444..6699999999999999999999************* PP

                 HHHGTSSTTSEEEEEEEESS--CS.SHTHHHHHHHHGCTEEEEEEEE..S CS
         VWA  94 kssagaRenakkviilltdGksnd.gdpkeaaneakeqgikvfavGv..g 140
                 +  ++   +++ v+i++ +  s+d gd+ ++++++ +++i+v +vG   +
  EEA22942.1 186 HTPSH---GTREVLIVFGSLLSSDpGDIHQTLKSLIADKIRVGIVGLaaQ 232
                 *****...***********9999988****************99998541 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (453 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       609  (0.0339673); expected 358.6 (0.02)
Passed bias filter:                      306  (0.0170673); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.54u 0.27s 00:00:00.81 Elapsed: 00:00:00.45
# Mc/sec: 3018.03
//
Query:       EEA22943.1  [L=195]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.4e-22   76.6   0.8    2.1e-21   75.5   0.8    1.6  1  DUF5572   Family of unknown function (DUF5572)


Domain annotation for each model (and alignments):
>> DUF5572  Family of unknown function (DUF5572)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.5   0.8   1.2e-25   2.1e-21       2      48 .]     136     182 ..     135     182 .. 0.98

  Alignments for each domain:
  == domain 1  score: 75.5 bits;  conditional E-value: 1.2e-25
     DUF5572   2 yplsFaelveLIesGkpIPgIkqIPdtvleaqpsestaprRkKPWEk 48 
                 yp sFa++veLI++++pIPgI++IPdtvl +++  s++++R+KPWEk
  EEA22943.1 136 YPPSFAHIVELITNNQPIPGIEEIPDTVLAGHDEPSKVTKRRKPWEK 182
                 9*********************************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (195 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       974  (0.0543254); expected 358.6 (0.02)
Passed bias filter:                      550  (0.0306766); expected 358.6 (0.02)
Passed Vit filter:                        39  (0.00217525); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.29s 00:00:00.79 Elapsed: 00:00:00.47
# Mc/sec: 1239.49
//
Query:       EEA22944.1  [L=419]
Description: O-methyltransferase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.5e-28   96.9   0.0    1.6e-27   96.2   0.0    1.3  1  Methyltransf_2   O-methyltransferase domain
     0.0099   16.6   0.0      0.029   15.0   0.0    1.9  1  Methyltransf_25  Methyltransferase domain
  ------ inclusion threshold ------
      0.034   13.6   0.0      0.058   12.9   0.0    1.3  1  Epimerase        NAD dependent epimerase/dehydratase family
      0.044   14.5   0.0       0.11   13.3   0.0    1.7  1  Methyltransf_12  Methyltransferase domain
      0.054   13.0   0.0      0.094   12.2   0.0    1.3  1  CheR             CheR methyltransferase, SAM binding domain


Domain annotation for each model (and alignments):
>> Methyltransf_2  O-methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   96.2   0.0   4.4e-31   1.6e-27      12     204 ..     188     391 ..     173     394 .. 0.87

  Alignments for each domain:
  == domain 1  score: 96.2 bits;  conditional E-value: 4.4e-31
                     S--..HHHHHS--..HHHHHTSSHHHHHHHHHHHH...TTHHHHHHHHHHSS-GGG-SE..EEEET-TTSHHHHHHHHH-TT-EEEEEE-HHHHH CS
  Methyltransf_2  12 rnqiifkkafGis..lfeaikrdeeerakfnkglq...essslvakkvleafdleglks..lvDvGGGtGalakaivsayPtikvivfDlpeVve 99 
                      n++ f+ af ++  +f++  + ++ +a+f  +++   +      +++++ +d +++ s  +vDvGG +G +  a ++ yP++k +v D  + v+
      EEA22944.1 188 PNHCSFSTAFNTPdpIFKFFDDHPDRQARFFGAMAgvgKGEGFSLRHIVTGYDWSKVGSglVVDVGGSSGFVSMALAESYPNLKFLVQDYEHTVQ 282
                     45599999**99999**************9777761115578999********999864439********************************* PP

                     HHHHHS-----TTEEEEES-TTTS-----SEEEEESSGGGS-HHHHHHHHHHHHHH--TT-EEEEEE--.-...-TTS---HHHHHHHHHHHHCS CS
  Methyltransf_2 100 aAkehlsageeervefvgGdffkdslPeaDaillkrvlhDwsdekcvklLkrvkkalpagGkvivveav.l...gadpsgeletelvdlimlvqt 190
                       k+ l +++e+rv+f   dff  +  +aD++++ +++hDw++++ vk+Lk++  a+++  ++++ e v +   + ++s+e +++ +++ m  + 
      EEA22944.1 283 GGKKALPTHLESRVDFATHDFFTPQTVSADVYFMRHICHDWAQHNAVKILKNLVPAMKPTSRIVMCELViMppkSMNGSQERQQRAMEMTMWTMV 377
                     **********************99999****************************************984322134555556666669999999* PP

                     S-----HHHHHHHH CS
  Methyltransf_2 191 eGkeRteaeyeell 204
                     + +eRt +e+ee++
      EEA22944.1 378 NAQERTREEWEEVV 391
                     ***********986 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   8.2e-06     0.029       1      95 [.     249     341 ..     249     342 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 8.2e-06
                      EEEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHHTTTTEEEEESBCCGBSSSTTTEEEEEEESTGGG.SSHHHHHHHHHHHHHHE CS
  Methyltransf_25   1 vLdlGcGtGrltlalakrlgkakvtgvDiseemleaareraeeeglnvefvqgdaedlpfedgsfDlvvssgalhh.lsdedlekalkeiarvL 93 
                      v+d+G  +G +++ala+ +++ k++  D+ ++     ++   + + +v+f ++d+ +   +  s D+ +++ +++h + ++++ k+lk++  ++
       EEA22944.1 249 VVDVGGSSGFVSMALAESYPNLKFLVQDYEHTVQGGKKALPTHLESRVDFATHDFFTP--QTVSADVYFMR-HICHdWAQHNAVKILKNLVPAM 339
                      89*****************99*******988765554444444555999999999664..45689*****5.65554999999******99999 PP

                      EE CS
  Methyltransf_25  94 kp 95 
                      kp
       EEA22944.1 340 KP 341
                      98 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.0   1.6e-05     0.058      23      85 ..      96     160 ..      85     196 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.6e-05
                 SEEEEEES-STTTTCHHCHHC.EEEE--TT-HHHHHHHHHHHT-SEEEE--S.---HHHHHHSHH CS
   Epimerase  23 yevigldrlssasntarledl.elveldltdrsalerlfkeeqpdavihlAa.vggvaassedpa 85 
                 y+++ ld+ ++  + a++  l e      + +sal+r+f+e  p++v+h Aa v+ v++++ +  
  EEA22944.1  96 YDLVPLDKSTTYAELAAKTGLpEYRIRTAMRQSALNRIFDEPTPNVVVHTAAsVALVKNKALQDW 160
                 788888888888887777777766666677899*******************9*99998877665 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.3   0.0     3e-05      0.11       1      97 [.     250     343 ..     250     345 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.3 bits;  conditional E-value: 3e-05
  Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvelealdlldldggssfDlvvasnvlhhl..kdirevldnirkl 92 
                      +++G+ +G +++al+e+ p++++++ D+   +        ++   +  ++v++ + d +  +   s D+ ++ + +h +   +  ++l+n+  +
       EEA22944.1 250 VDVGGSSGFVSMALAESYPNLKFLVQDYEHTVQ----GGKKALPTHLESRVDFATHDFFTPQT-VSADVYFMRHICHDWaqHNAVKILKNLVPA 338
                      59**************************99999....44444555556778887777554444.5**************888888*******99 PP

  Methyltransf_12  93 LkpgG 97 
                      +kp  
       EEA22944.1 339 MKPTS 343
                      99965 PP

>> CheR  CheR methyltransferase, SAM binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   2.6e-05     0.094      97     173 ..     273     347 ..     249     363 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 2.6e-05
                 HHHHHEEEEETTCEEE-HHHHTTEEEEE--TTT-SGGG--EEEEEE-SSGGGC-CHHHHHHHHHHHCCEEEEEEEEE CS
        CheR  97 lleryfekseddsykvkkeikelvkFeklnllekksvlgklDvifcrnvliYfdeetqekvlerfaeklkpgglLll 173
                 l++ y ++ ++++    +++ ++v+F+ ++ ++  + + + Dv f r +     +++  k+l+++  ++kp++++++
  EEA22944.1 273 LVQDYEHTVQGGKKALPTHLESRVDFATHDFFT--PQTVSADVYFMRHICHDWAQHNAVKILKNLVPAMKPTSRIVM 347
                 46677777788888899****************..777789*******************************99875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (419 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       647  (0.0360868); expected 358.6 (0.02)
Passed bias filter:                      553  (0.0308439); expected 358.6 (0.02)
Passed Vit filter:                        51  (0.00284455); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.58u 0.25s 00:00:00.83 Elapsed: 00:00:00.43
# Mc/sec: 2905.18
//
Query:       EEA22945.1  [L=315]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    5.1e-22   78.6   0.1    6.7e-22   78.2   0.1    1.1  1  NmrA            NmrA-like family
    7.8e-16   58.5   0.0    1.3e-15   57.8   0.0    1.3  1  NAD_binding_10  NAD(P)H-binding
     0.0028   17.1   0.0       0.03   13.8   0.0    2.5  2  Epimerase       NAD dependent epimerase/dehydratase family


Domain annotation for each model (and alignments):
>> NmrA  NmrA-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   78.2   0.1   1.1e-25   6.7e-22       1     222 [.      10     232 ..      10     241 .. 0.84

  Alignments for each domain:
  == domain 1  score: 78.2 bits;  conditional E-value: 1.1e-25
                 EEESSTTSHHHHHHHHHHHHHT-EEEEEES-S.....-SHHHHHHHHSTTEEEES-TT-HHHHHHHHTT-SEEEE---GGS-HHHHHHHHHHHHHHHS- CS
        NmrA   1 IlviGaTGrqGksvvrallkaghkvralvRdt.....kselakslkeaGvelvkgdlddkeslvealkgvdvvfsvtgfyskeiedgkklvdAakeaGv 94 
                 ++ +GaTG++G+++  all+a + v +++R       ++ l+k + +     vk   dd++ + +alk+ d+v ++++  +  i+ +++l++Aa++aGv
  EEA22945.1  10 VALFGATGNLGSHILGALLEASFIVTVILRPDckfqlTTPLIKGVPSTALRAVKIPFDDEQAMIRALKTQDAVVASVS--KGGIQTQMNLIRAAVKAGV 106
                 689***************************88899999****************************************..******************* PP

                 SEEEEEE---GG.GT.SSS---TTTHHHHHHHHHHHHC.TS-EEEEEE-EEGGG-BSSS-SS-BEEE-TTS.-EEEEESS-TTS-EE.-HHHHHHHHHH CS
        NmrA  95 khfiySslgddndrsnaeepavphfdsKaeieeyvral.gipytfvyagffmenflsllaqlkvgdtappedkvtllgpgnpkavll.daeeDiGafvi 191
                 k+fi+S++g+d    +    +vp+ + K  i ey+r + + + +f  +g+ +  f+    +  +   +   +++++   g    +++ ++ + ++++v+
  EEA22945.1 107 KRFIPSEFGADT-LNDSFLRNVPALQDKRVILEYLRVMaRENPSFTWTGISNAAFIDWGLESGFLGFDIASQTAVIYSSGTK--KFNaTTRTTVAKAVA 202
                 ***********9.66677789***************9984555666666666666665555444455555557788887774..44446999******* PP

                 HHHHHHHHHTTEEEEE-SEEE-HHHHHHHHH CS
        NmrA 192 kilkdprklkgkriklagntlsgneivelfe 222
                  +lk+p++  ++++ ++  t + n+++e +e
  EEA22945.1 203 LVLKHPETE-NQYVYISDFTTTQNKLLEQLE 232
                 *****9986.566777777777777777665 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   57.8   0.0   2.1e-19   1.3e-15       1     184 []      14     208 ..      14     208 .. 0.77

  Alignments for each domain:
  == domain 1  score: 57.8 bits;  conditional E-value: 2.1e-19
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHCH.......HHHCTTTCEEEE--TT-CCHHHHHHTT-SEEEES---TCCHHHHHHHHHHHHHHC CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpekla.......eleaeeglevvegdvtdvedlaealkgadaVvsalggggkdeegaknivdaakea 88 
                     GAtG+ G++++  ll+++ + vt++ R   k++        ++ + +l++v++ + d++++ +alk +daVv+++++gg   ++  n+++aa +a
      EEA22945.1  14 GATGNLGSHILGALLEAS-FIVTVILRPDCKFQlttplikGVP-STALRAVKIPFDDEQAMIRALKTQDAVVASVSKGGI--QTQMNLIRAAVKA 104
                     9****************6.*********988874444333333.5799****************************9998..6899********* PP

                     T--EEEEEEETTTTSGCGCHHHHHHHHCCHHHHHHHHHHHHHHHH.....SSSEEEEEEE-CEE-ST.--...SEEEE......ETTSS----EE CS
  NAD_binding_10  89 gvkRfvlvsaigvgdevpgefgewnkellkaylaakraaeellra.....sgldwTivrpggLtdep.tt...kyrvv......ekgepfkggsi 168
                     gvkRf+  s +g++   +++f    +++  ++l++kr   e+lr        ++wT ++ +++ d   ++   ++ ++       ++ + k + +
      EEA22945.1 105 GVKRFIP-SEFGADT-LNDSF---LRNV--PALQDKRVILEYLRVmarenPSFTWTGISNAAFIDWGlESgflGFDIAsqtaviYSSGTKKFNAT 192
                     ******9.8899994.33333...2333..6799999999999655555579**********999654431122223322222234444445689 PP

                     EHHHHHHHHHHHCTXG CS
  NAD_binding_10 169 sradVAdvlvavlddp 184
                     +r  VA++++ vl++p
      EEA22945.1 193 TRTTVAKAVALVLKHP 208
                     ************9997 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.8   0.0   5.1e-06      0.03       3      82 ..      12      96 ..      10     112 .. 0.79
   2 ?   -0.2   0.0     0.095   5.7e+02     200     232 ..     179     211 ..     128     218 .. 0.75

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 5.1e-06
                EETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC.........EEEE--TT-HHHHHHHHHHHT-SEEEE--S---HHHHHH CS
   Epimerase  3 VtGatGfiGsalvkallekgyevigldrlssasntarledl.........elveldltdrsalerlfkeeqpdavihlAavggvaasse 82
                + GatG +Gs+++ alle+   v+++ r     ++++   l         + v++ + d++a+ r++k    dav+     gg++++++
  EEA22945.1 12 LFGATGNLGSHILGALLEASFIVTVILRPDC--KFQLTTPLikgvpstalRAVKIPFDDEQAMIRALK--TQDAVVASVSKGGIQTQMN 96
                57******************66666666633..333333334566***********************..78***99988999888776 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.095
                 EEEETTST-EEEEEEHHHHHHHHHHHHHHHTT- CS
   Epimerase 200 vtllgdgtalRdflyveDvaeaillvlehvdag 232
                  +++++gt +        va+a+ lvl+h+++ 
  EEA22945.1 179 AVIYSSGTKKFNATTRTTVAKAVALVLKHPETE 211
                 556666777766677777999999999998774 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (315 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       579  (0.032294); expected 358.6 (0.02)
Passed bias filter:                      499  (0.027832); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.39s 00:00:01.04 Elapsed: 00:00:00.58
# Mc/sec: 1633.13
//
Query:       EEA22946.1  [L=516]
Description: aminotriazole resistance protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.8e-39  134.6  64.4    4.1e-27   95.0  42.5    2.7  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.0  42.5   2.3e-31   4.1e-27      17     259 ..      76     367 ..      62     370 .. 0.84
   2 !   42.9  24.2   1.6e-15   2.9e-11       2     176 ..     321     510 ..     318     516 .] 0.84

  Alignments for each domain:
  == domain 1  score: 95.0 bits;  conditional E-value: 2.3e-31
       MFS_1  17 palpl.alaedlg.ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll...fa.sslwlllvlrvlqGlgagalfpagaal 109
                 +++pl +++++++ ++  e+++ ++ +al+++ ++l++Grl+d +G++ +l++g+l++++++l++    f+ ss  l++v+r+lqG+ga++++p+++a+
  EEA22946.1  76 SLAPLhIIGDHFNvSNNGELSWYIASFALVTGTFILVAGRLGDMYGSKHILIIGFLIYGFWSLIAGagyFTrSSDKLFVVSRALQGVGASLVLPNAVAI 174
                 4556679******444567******************************************777775755688888*********************** PP

       MFS_1 110 iadwfpk.eergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeee................... 188
                 + + +p+  +++++++l++a++  G+ilg l+++++a+   W +++++++i++++++ +  +++  ++p+ k++++k                      
  EEA22946.1 175 LGRTYPPgLRKNMVMSLFGAFAPGGYILGCLFSSIFAQFTIWAWAYFAMGIACFVLATV--AYFAIPKPSLKPDASKSFDwlgfgfgiaglllfnvawn 271
                 *******88****************************9999***************886..666555555555555555569***************** PP

       MFS_1 189 .............................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglllaglllallalvga 258
                                              ++++++plvp  +++  +  +  +l+a+l ++  f+  l+++  +l + +g s  ll+++    +a+ g+
  EEA22946.1 272 qgptvgwatpyvyvllilgvlafvgfvlvERRVERPLVP-VQQFNLHIAF--VLLAILAGWSSFTVWLYYIWQFLEQLRGAS-PLLTTAQNTPSAISGF 366
                 ***************************************.6666666656..6666666666888899999999********.4555555555555554 PP

       MFS_1 259 i 259
                 +
  EEA22946.1 367 V 367
                 4 PP

  == domain 2  score: 42.9 bits;  conditional E-value: 1.6e-15
       MFS_1   2 llaaflsalarsilgpalpl.alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfa..sslw.lllvlrvlq 95 
                 +l+a+l++++++++++ + + +l +  g+sp       t  a+  +vas+ +G+l+ ++G  ++++l++l+f+++ +l+++++  +++w   +++ ++ 
  EEA22946.1 321 VLLAILAGWSSFTVWLYYIWqFLEQLRGASPLLTTAQNTPSAISGFVASITTGFLIGKIGVPPIMILAMLAFFIAnVLAATMPinQTYWtQTFFATIIV 419
                 5778889999999999999988877778888877777777999********************************555555766899**9********* PP

       MFS_1  96 GlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg........Wravfyilaivsllafv..lfllllpeep 176
                  +g+ ++fpa+++++++ +p+e++g a +l+ ++++ ++ +g +++g  +s+lg         r ++y++ ++s l++v  +  +l+ +++
  EEA22946.1 420 PWGMDMSFPAAVIMLSAAVPPEHQGIAASLALTTTNYAMSIGLGIAGTAVSHLGdgsdlladCRHAWYVAIGLSGLGIViaITSMLYERRN 510
                 **************************************************************66666666666666655223334443333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (516 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       901  (0.0502538); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.79u 0.35s 00:00:01.14 Elapsed: 00:00:00.57
# Mc/sec: 2730.04
//
Query:       EEA22947.1  [L=203]
Description: minor allergen Alt a, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      5e-09   36.1   0.0    7.7e-09   35.5   0.0    1.3  1  FMN_red       NADPH-dependent FMN reductase
    9.3e-07   28.8   0.0    1.2e-06   28.4   0.0    1.1  1  Flavodoxin_2  Flavodoxin-like fold
    1.7e-05   25.1   0.3    0.00016   21.9   0.2    2.4  2  Flavodoxin_1  Flavodoxin
     0.0079   16.4   0.0       0.05   13.8   0.0    1.9  2  Flavodoxin_5  Flavodoxin domain


Domain annotation for each model (and alignments):
>> FMN_red  NADPH-dependent FMN reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.5   0.0   1.7e-12   7.7e-09       2     144 ..       4     143 ..       3     148 .. 0.78

  Alignments for each domain:
  == domain 1  score: 35.5 bits;  conditional E-value: 1.7e-12
                 EEEEEES--STT-HHHHHHHHHHCCT-T.T-CEEEEETTTS.--..---HCHGHTCGGSHHHHHH.HHHHHH-SCEEEEEEECTTCE-HHHHHHHHCHT CS
     FMN_red   2 kilvisGSlrkgsntrklaewaaealkeagaevelidladlilpcalcdkdlesegqtsddvael.lekiaaadaliivtPeYngsysgllKnalDrls 99 
                 ki++i+ S +  +  +++ae+ ++ +++ag ++++ ++a+  lp  ++   + ++ ++sd+ + + +ek+ + da++++ P+ +g+++++ K+++D ++
  EEA22947.1   4 KIAIIYYSMH--GHIQQMAEAEKRGIEAAGGHADIYQIAET-LPAEVLE--KMHAVPKSDQYQIIsSEKLVEYDAFLLGVPTRFGNMPAQWKAFWDSTG 97 
                 7777777774..88899999999999999***********8.6621444..33456777777665369******************************* PP

                 -.SSCHCCTT-EEEEEEE-SSTTTTHH.HHHHHHHHHHHTT-EEEE CS
     FMN_red 100 rtrgkkelrgKpvalvavgggrrgglr.aeeqlrqvlaelgaivvp 144
                   +g   l gK+++l+   g+  gg++ ++ ++++ +a++g   vp
  EEA22947.1  98 GLWGTGGLWGKYAGLFISTGTLGGGQEsTALAMMSTFAHHGINFVP 143
                 ***********99776555565666551555666666688877776 PP

>> Flavodoxin_2  Flavodoxin-like fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.4   0.0   2.6e-10   1.2e-06       2     138 ..       4     120 ..       3     157 .. 0.74

  Alignments for each domain:
  == domain 1  score: 28.4 bits;  conditional E-value: 2.6e-10
                   EEEEEE--TTGGCCHHHCHHHHHHHHHCCCTTTEEEEEEHHCC.T-----CCCCHCCHHHHTTCHHHHHHH.HHHHHCSSEEEEEEE-BTTB--HHH CS
  Flavodoxin_2   2 kiLiinahprpeksfssalaqafvealekagphevtvrdLyad.flpvlttrdlaaklayeekpadveseq.iekllaadaivlqfPlwwfgvPail 96 
                   ki ii+ + ++  +   ++a+a  +++e+ag    ++  ++++ +  vl++      +a ++   d+++    ekl + da +l++P  + ++Pa+ 
    EEA22947.1   4 KIAIIYYSMHG--HI-QQMAEAEKRGIEAAG-GHADIYQIAETlPAEVLEKM-----HAVPK--SDQYQIIsSEKLVEYDAFLLGVPTRFGNMPAQW 89 
                   78889999888..45.789999999999999.66888888888666666651.....23333..6666666668*********************** PP

                   HHHHHHHS-TTTSCEETTCSSCCCCTTTTSEEEEEEEESS-G CS
  Flavodoxin_2  97 KgwiDrvltagfafyteeggegrgggLkgkkalvivttGgpe 138
                   K++ D     g           ++ggL gk a + ++tG  +
    EEA22947.1  90 KAFWDST--GGL-W--------GTGGLWGKYAGLFISTGTLG 120
                   ******6..444.4........3689************9882 PP

>> Flavodoxin_1  Flavodoxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.9   0.2   3.5e-08   0.00016       1     108 [.       7     103 ..       7     137 .. 0.70
   2 !    6.2   0.0    0.0025        11      13      71 ..      39      94 ..      38     193 .. 0.80

  Alignments for each domain:
  == domain 1  score: 21.9 bits;  conditional E-value: 3.5e-08
                   EEEETSSSHHHHHHHHHHHHHHHTTTEEEEEEEEGTTSCGGGGGTHSEEEEEEEEETTTBEEGGGHHHHHHHHHHHCHHGCCSTTTTEEEEEEEEEC CS
  Flavodoxin_1   1 ilYgSetGnteklAkqlaeelgehgfnadvvslsdydeslseieeealllvvtsTfgnGdppengesffqdllelkgdeledgdlsgvrfavfglGd 97 
                   i+Y+S+ G+ +++A++ +++++++g +ad++++++      e+ e++  +v  s  ++   +e+    ++d + l       + + ++  ++ +++d
    EEA22947.1   7 IIYYSMHGHIQQMAEAEKRGIEAAGGHADIYQIAETLP--AEVLEKM-HAVPKSDQYQIISSEKLV--EYDAFLLG-V---PTRFGNMPAQWKAFWD 94 
                   89********************************9995..4776544.444444455555555544..34444444.3...3457899999999999 PP

                   TTSSSTTHHHH CS
  Flavodoxin_1  98 sayenFcaagk 108
                   s++    +  +
    EEA22947.1  95 STGGL--WGTG 103
                   98876..5555 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.0025
                  HHHHHHHHHHHTTTEEEEEEEEGTTSC.GGGGGTHSEEEEEEEEETTTBEEGGGHHHHHH CS
  Flavodoxin_1 13 lAkqlaeelgehgfnadvvslsdydes.lseieeealllvvtsTfgnGdppengesffqd 71
                  +A++l  e+ e +++  v + ++y++   +++ e++  l++++ +  G +p + +  f+d
    EEA22947.1 39 IAETLPAEVLE-KMH-AVPKSDQYQIIsSEKLVEYDAFLLGVP-TRFGNMPAQWK-AFWD 94
                  45555555543.332.455566666668899999999999999.56688886666.4444 PP

>> Flavodoxin_5  Flavodoxin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0     0.085   3.8e+02       2      34 ..       7      39 ..       6      44 .. 0.79
   2 !   13.8   0.0   1.1e-05      0.05      13      66 ..      38      93 ..      33      99 .. 0.82

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.085
  Flavodoxin_5  2 ilYsSrdGqTkkiaeriaeelreegelvdvedv 34
                  i+Y S +G+ ++ ae+ +  ++++g  +d+ ++
    EEA22947.1  7 IIYYSMHGHIQQMAEAEKRGIEAAGGHADIYQI 39
                  99***********99988888877666666665 PP

  == domain 2  score: 13.8 bits;  conditional E-value: 1.1e-05
  Flavodoxin_5 13 kiaeriaeelreegelvdved...vekesedlesydavvigasvyygkllpelakFv 66
                  +iae++ +e+ e+++ v  +d   +  +se+l +yda+++g + + g+++ + ++F 
    EEA22947.1 38 QIAETLPAEVLEKMHAVPKSDqyqI-ISSEKLVEYDAFLLGVPTRFGNMPAQWKAFW 93
                  7899998888888666665553324.6999********************9999986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (203 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       394  (0.0219756); expected 358.6 (0.02)
Passed bias filter:                      353  (0.0196888); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.48u 0.30s 00:00:00.78 Elapsed: 00:00:00.47
# Mc/sec: 1304.38
//
Query:       EEA22948.1  [L=186]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.1e-72  243.0   0.8    1.4e-72  242.7   0.8    1.0  1  Scytalone_dh  Scytalone dehydratase
    5.3e-05   23.3   0.8    6.6e-05   23.0   0.8    1.1  1  SnoaL_4       SnoaL-like domain


Domain annotation for each model (and alignments):
>> Scytalone_dh  Scytalone dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  242.7   0.8   1.5e-76   1.4e-72       2     154 ..       8     162 ..       7     167 .. 0.97

  Alignments for each domain:
  == domain 1  score: 242.7 bits;  conditional E-value: 1.5e-76
                   --HHHHHHHHHHHHHHHHHHHHT-HHHHHTTEEEEEEEEEHHHHSEE..EEEEEHHHHHHHHTSTTTTT-TTEEE--EEEEEEEEEEETTEEEEEEE CS
  Scytalone_dh   2 itfedylglkkvlfewadsydskdwdrlrkviaptlridyrslldkl..weampaeefvamisdkdvlgdptlktqhligesrwekvsdtevigyhq 96 
                   ++f+dy+ l+++ few dsyd+kdw rlrk+i+ptl+idyr ++d+   w +m a++f+am+s+  +lgdp +ktqhl+g+ ++e +s+tevig+hq
    EEA22948.1   8 LSFQDYIQLQTCTFEWGDSYDAKDWARLRKIISPTLKIDYRIVMDERwyWPEMEADDFIAMVSSEGFLGDPCIKTQHLLGGHWYEPISETEVIGHHQ 104
                   78******************************************98722589********************************************* PP

                   EEEEEEEESSTT--SEEEEEEEEEEEEEEEEEETTEEEEEEEEEEEEEEEESHHHHTH CS
  Scytalone_dh  97 lrvahqkytdatlkevklkghahsanlhyyrkvdgvwkfaglkpeirwseydfddvfe 154
                   lr+ah +ytda+l+ev+ +gh+h++n+ +yr++dgvwkfag++p +rw+e+df+++f+
    EEA22948.1 105 LRAAHSRYTDASLREVAKRGHGHATNELFYRRIDGVWKFAGIRPFVRWNEWDFEQIFR 162
                   *********************************************************8 PP

>> SnoaL_4  SnoaL-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.0   0.8   7.4e-09   6.6e-05       8     124 ..      15     144 ..       9     147 .. 0.77

  Alignments for each domain:
  == domain 1  score: 23.0 bits;  conditional E-value: 7.4e-09
                 HHHHHHHHHHHHHHTT-HHHHHTTEEEEEEEEETTS.......--EESHHHHHHHHHS...HHHHHH-EEEEE---EEEE.ETTEEEEEEEEEEEEEET CS
     SnoaL_4   8 aIrdlvarygyylDtkdweeladlFtedavvdytgvg.....egvlegrdairaalre...aldgfaltqHllsnpliel.dgdtAtgrayllatlvrd 97 
                 + + +   +g  +D+kdw+ l+++  +  ++dy+ v        ++  +d+++a++++     d+ + tqHll+ +  e   +++  g   l a + r 
  EEA22948.1  15 QLQTCTFEWGDSYDAKDWARLRKIISPTLKIDYRIVMderwyWPEM-EADDFIAMVSSegfLGDPCIKTQHLLGGHWYEPiSETEVIGHHQLRAAHSRY 112
                 56677788999***********************655775554445.47888888888333234444************868888***********999 PP

                 TEE.....EEEE..EEEEEEEEEEETTEEEEE CS
     SnoaL_4  98 gdg.....grqvlaggryedelvredggWris 124
                 +d+     + + +  + +e  ++r dg+W+++
  EEA22948.1 113 TDAslrevAKRGHGHATNELFYRRIDGVWKFA 144
                 97744333455556688888899*******97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (186 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       291  (0.0162307); expected 358.6 (0.02)
Passed bias filter:                      264  (0.0147247); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.40u 0.27s 00:00:00.67 Elapsed: 00:00:00.42
# Mc/sec: 1319.19
//
Query:       EEA22949.1  [L=612]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.8e-69  234.0   0.0    1.2e-35  123.4   0.0    2.1  2  FAD_binding_3   FAD binding domain
    2.1e-28   99.4   0.0    3.5e-28   98.7   0.0    1.4  1  Phe_hydrox_dim  Phenol hydroxylase, C-terminal dimerisation d
      5e-06   25.8   0.1    8.3e-06   25.1   0.1    1.3  1  FAD_binding_2   FAD binding domain
    6.3e-06   25.1   0.0    9.3e-06   24.6   0.0    1.2  1  HI0933_like     HI0933-like protein
    6.4e-06   25.6   0.0    1.3e-05   24.6   0.0    1.5  1  Pyr_redox_2     Pyridine nucleotide-disulphide oxidoreductase
    0.00012   21.5   0.0    0.00018   21.0   0.0    1.3  1  FAD_oxidored    FAD dependent oxidoreductase
     0.0002   20.6   0.1    0.00029   20.0   0.1    1.2  1  GIDA            Glucose inhibited division protein A
    0.00026   21.1   0.0    0.00074   19.7   0.0    1.8  1  NAD_binding_8   NAD(P)-binding Rossmann-like domain
     0.0004   19.5   0.2    0.00075   18.6   0.2    1.4  1  Lycopene_cycl   Lycopene cyclase protein
    0.00063   19.4   0.0    0.00097   18.8   0.0    1.2  1  DAO             FAD dependent oxidoreductase
    0.00077   18.8   0.0     0.0012   18.1   0.0    1.2  1  AlaDh_PNT_C     Alanine dehydrogenase/PNT, C-terminal domain
     0.0015   17.8   0.0     0.0025   17.1   0.0    1.3  1  Thi4            Thi4 family
     0.0018   17.6   0.0     0.0033   16.7   0.0    1.3  1  Pyr_redox_3     Pyridine nucleotide-disulphide oxidoreductase
     0.0019   17.2   0.0     0.0036   16.2   0.0    1.5  1  Trp_halogenase  Tryptophan halogenase
  ------ inclusion threshold ------
      0.018   15.6   0.0      0.038   14.6   0.0    1.6  1  Pyr_redox       Pyridine nucleotide-disulphide oxidoreductase
      0.044   14.0   0.0       0.11   12.8   0.0    1.7  1  TrkA_N          TrkA-N domain
       0.14   12.0   0.0       0.24   11.3   0.0    1.3  1  3HCDH_N         3-hydroxyacyl-CoA dehydrogenase, NAD binding 


Domain annotation for each model (and alignments):
>> FAD_binding_3  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  123.4   0.0   1.2e-38   1.2e-35       2     232 ..       8     241 ..       7     246 .. 0.86
   2 !  108.7   0.0   3.5e-34   3.7e-31     248     349 .]     280     383 ..     272     383 .. 0.95

  Alignments for each domain:
  == domain 1  score: 123.4 bits;  conditional E-value: 1.2e-38
                    EEEEEE--SHHHHHHHHHHHHTTHHEEEEESSSSSCCSSS--EEEHHHHHHHHHTT-HHHHHHHSEECCCCEEEEE.EECCCC...CEEEEEHHCH CS
  FAD_binding_3   2 tdVlIVGaGpaGlmlallLseaGvrvvlvekrsttvvlpradglnqrtmellrqlGledrilaegapnelmgealy.nelsdt...pkaradlele 93 
                    +dVl+VGaGpaG+m+al L+++ ++v++++ r ++++++ a+g+++rt e+l++l l +r+  +g  n+++++a++  + +dt    ++  +++  
     EEA22949.1   8 CDVLVVGAGPAGFMAALTLARYNINVRIIDARPERIQTGHAGGVQPRTQEILQTLNLRHRLDIQG--NHVSETAFWsINEQDTferTHIGGEIQNP 101
                    89***************************************************************..44444444303335557444555566666 PP

                    HCST-CEE--HHHHHHHHHHHHHHHTEEETCSEEEECCEECCCCCCCEEE...ECCTTEEEEEEEEEEEE--GTT-HHHHHHTGGEEEEEEEEEEE CS
  FAD_binding_3  94 sspervtvypqteleriLvehaeerglqvrfktevesleqdeegvtaevr...dketgeeetvrakYlvGaDGgrStvrktlgiefegeetvyeag 186
                    + ++ +  +pq e+er+  e+++ rg++v++  e+  ++ +++ + + +    ++ t+ ++  r kY++G DG+ S++r+ lg+  e+++++  + 
     EEA22949.1 102 TPYPWILSIPQRETERAFDEDLNTRGCTVERPVELIDFTYTDDAEYPLLAsvkNQYTNITSVYRTKYIIGSDGAASKTRSLLGFGSETHGNDDVWC 197
                    9999999***************************999999999998666522266666668889*********************999999999** PP

                    EEEEEEEC-SCCCTTCCEEEEECCTTEEEEEECCETEEEEEEEEEC CS
  FAD_binding_3 187 vldvlfdadlsdiveplvlilsaesrgvmviPlentlerfyvqvea 232
                    v+d   d++++d++   ++i+s++ + +m+iP  +  +r+y q+++
     EEA22949.1 198 VADCYLDTNFPDVRRR-CAIRSKQGG-IMLIPNPRDMNRIYTQLDT 241
                    ***************9.999988777.5****99989999999876 PP

  == domain 2  score: 108.7 bits;  conditional E-value: 3.5e-34
                    HHHHHHHHHTTSSCEE.EEEEEEEEEEEEEEESSSEET.TEEE-GGGTEEE-STTSHHHHHHHHHHHHHHHHHHHHHTTSS-GGGGHHHHHHHHHH CS
  FAD_binding_3 248 vkarlreivgektldv.eieevsawtvaqrvaekyrkg.rvflaGDAaHihpPtgGqGlNtaiqDavnLawkLaavlkGeAkeelLdtYeeerrav 341
                    +++r++  v++++++  ++ ++s+++++qr++e++ +  rvf++GDA+H+h+P+++qGlN+++ D++nL wkLa+vlkG+ + ++L++Y  err+ 
     EEA22949.1 280 LRKRVKDVVAPYKMEInKLVWISQYRLRQRIVESFWDQkRVFIVGDACHTHSPKAAQGLNVSMADSYNLTWKLALVLKGKSDASILESYAIERRQL 375
                    578999999999**9999****************98888********************************************************* PP

                    HHHHHHHH CS
  FAD_binding_3 342 aqavvdfa 349
                    aq+++df+
     EEA22949.1 376 AQELLDFD 383
                    ****9985 PP

>> Phe_hydrox_dim  Phenol hydroxylase, C-terminal dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   98.7   0.0   3.4e-31   3.5e-28       1     166 []     411     580 ..     411     580 .. 0.92

  Alignments for each domain:
  == domain 1  score: 98.7 bits;  conditional E-value: 3.4e-31
  Phe_hydrox_dim   1 FtsGvgveYqpsllvaevkskqnlatg.....lrpGrrlpsakVvrvaDanpvdlqdeipsdGrfRilvfagdlsdaeqksrlsaladalsskes 90 
                     FtsGvg +Yqp  l+a  +s+ ++ ++     l+pG+rl +++  r++D+ p+++ d++ps+Grf+++vf+g++     ++rl  l d+l+s++s
      EEA22949.1 411 FTSGVGQQYQPGPLTAVDESSMTIINSgavepLTPGKRLYPFNTQRHIDGTPLNILDDFPSNGRFHLVVFVGNAIL---NKRLGPLIDYLASEDS 502
                     9**************97777777777779999***************************************99333...589********9999* PP

  Phe_hydrox_dim  91 flsrftpada..............dvdsvievllihaaprkeieledlPevlrpfdeklgldy.ekvyvddesyhedgaaYekyGidkkrG 166
                     +l+rf + +               +++++i+++l h+ ++ +i+l+dlP+ l+         +  ++y+d++s      +++++G+d++ G
      EEA22949.1 503 VLTRFDKTSGtvwgfediystsqqNRHRIIDMFLFHTDDKYQINLDDLPAPLN--------SWkYRIYSDKDS-----SVHASLGVDPEVG 580
                     *****88777*******************************************........55567*****99.....69*******9976 PP

>> FAD_binding_2  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.1   0.1   7.9e-09   8.3e-06       1      43 [.       9      50 ..       9      52 .. 0.95

  Alignments for each domain:
  == domain 1  score: 25.1 bits;  conditional E-value: 7.9e-09
                   SEEEE--SHHHHHHHHHHHHTTT-EEEEESSSGGGSGGGG--S CS
  FAD_binding_2  1 DviViGsGlAGLaAAleaaeaGlkvavvekeqefggatawsqG 43
                   Dv+V+G+G AG +AAl++a+ + +v +++  +e + +t  ++G
     EEA22949.1  9 DVLVVGAGPAGFMAALTLARYNINVRIIDARPE-RIQTGHAGG 50
                   9*******************************9.999999988 PP

>> HI0933_like  HI0933-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.6   0.0   8.8e-09   9.3e-06       2      33 ..       9      40 ..       8      45 .. 0.93

  Alignments for each domain:
  == domain 1  score: 24.6 bits;  conditional E-value: 8.8e-09
                 SEEEE--SHHHHHHHHHHHHTT--EEEE-SSS CS
  HI0933_like  2 dviviGgGaAGlmaAisaakrgkrVlllekak 33
                 dv+v+G+G+AG+maA+++a+ + +V ++++ +
   EEA22949.1  9 DVLVVGAGPAGFMAALTLARYNINVRIIDARP 40
                 8****************************875 PP

>> Pyr_redox_2  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.6   0.0   1.3e-08   1.3e-05       2      31 ..       9      44 ..       8      92 .. 0.77

  Alignments for each domain:
  == domain 1  score: 24.6 bits;  conditional E-value: 1.3e-08
                 SEEEE--SHHHHHHHHHHHHHTS-EEEEE......T CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxx......x RF
  Pyr_redox_2  2 dvvviGgGpAGlaaaltlaqagakvtlve......l 31
                 dv+v+G+GpAG+ aaltla+++++v +++      +
   EEA22949.1  9 DVLVVGAGPAGFMAALTLARYNINVRIIDarperiQ 44
                 89**************************86654433 PP

>> FAD_oxidored  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.0   0.0   1.7e-07   0.00018       1      32 [.       9      40 ..       9     106 .. 0.91

  Alignments for each domain:
  == domain 1  score: 21.0 bits;  conditional E-value: 1.7e-07
  FAD_oxidored  1 DvvVvGGgpaGvaAAiaAaraGakvlLveerg 32
                  Dv+VvG+gpaG++AA++ ar   +v +++ r+
    EEA22949.1  9 DVLVVGAGPAGFMAALTLARYNINVRIIDARP 40
                  9***************************9765 PP

>> GIDA  Glucose inhibited division protein A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.0   0.1   2.8e-07   0.00029       1      33 [.       9      41 ..       9      61 .. 0.84

  Alignments for each domain:
  == domain 1  score: 20.0 bits;  conditional E-value: 2.8e-07
                CEEEE-SSHHHHHHHHHHHHTT--EEEEES-GG CS
        GIDA  1 dviViGgGhAGceAAlaaarlGakvlLithkld 33
                dv V+G+G AG+ AAl++ar +++v +i  + +
  EEA22949.1  9 DVLVVGAGPAGFMAALTLARYNINVRIIDARPE 41
                79************************9944433 PP

>> NAD_binding_8  NAD(P)-binding Rossmann-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.7   0.0     7e-07   0.00074       1      29 [.      12      40 ..      12      53 .. 0.95

  Alignments for each domain:
  == domain 1  score: 19.7 bits;  conditional E-value: 7e-07
                   EE--SHHHHHHHHHHHCCTEEEEEE-SSS CS
  NAD_binding_8  1 IvGaGlsGlvaAylLakagfdvlllekrd 29
                   +vGaG +G  aA +La+++++v ++++r+
     EEA22949.1 12 VVGAGPAGFMAALTLARYNINVRIIDARP 40
                   8**************************97 PP

>> Lycopene_cycl  Lycopene cyclase protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.6   0.2   7.2e-07   0.00075       1      40 [.       9      46 ..       9      51 .. 0.93

  Alignments for each domain:
  == domain 1  score: 18.6 bits;  conditional E-value: 7.2e-07
  Lycopene_cycl  1 DvvviGaGpAglslAarlteakpglkvvlieaspsllfpn 40
                   Dv+v+GaGpAg   A  l  a+++++v +i+a p+ + ++
     EEA22949.1  9 DVLVVGAGPAGFMAALTL--ARYNINVRIIDARPERIQTG 46
                   9*****************..************99987765 PP

>> DAO  FAD dependent oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.8   0.0   9.2e-07   0.00097       1      43 [.       9      51 ..       9      67 .. 0.92

  Alignments for each domain:
  == domain 1  score: 18.8 bits;  conditional E-value: 9.2e-07
                EEEEECTSHHHHHHHHHHHHTT..EEEEESSSSTTSSGGGSSEEE CS
         DAO  1 dvviiGGGiiGlstAyeLarrg..VtllekgdiagsgaSgrnsgl 43
                dv+++G+G +G  +A+ Lar +  V +++++  + + ++g+++g+
  EEA22949.1  9 DVLVVGAGPAGFMAALTLARYNinVRIIDAR--PERIQTGHAGGV 51
                8*****************999999*******..556899999996 PP

>> AlaDh_PNT_C  Alanine dehydrogenase/PNT, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.1   0.0   1.2e-06    0.0012      29      67 ..       8      46 ..       5      78 .. 0.88

  Alignments for each domain:
  == domain 1  score: 18.1 bits;  conditional E-value: 1.2e-06
                 -EEEEESTSHHHHHHHHHHHHTT-EEEEEESSHHHHHHH CS
  AlaDh_PNT_C 29 akvlviGgGvaGlqAiatakglgakVtvlDvrparleql 67
                 + vlv+G+G aG  A+ t ++ + +V+++D rp+r++  
   EEA22949.1  8 CDVLVVGAGPAGFMAALTLARYNINVRIIDARPERIQTG 46
                 579*******************************99865 PP

>> Thi4  Thi4 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.1   0.0   2.4e-06    0.0025      18      50 ..       8      39 ..       2      63 .. 0.87

  Alignments for each domain:
  == domain 1  score: 17.1 bits;  conditional E-value: 2.4e-06
                EEEEEE--SHHHHHHHHHHHHCTTS-EEEEESS CS
        Thi4 18 sDvvivGaGssGLtaayylakkpdlkvailers 50
                 Dv++vGaG++G  aa +la+  +++v i++++
  EEA22949.1  8 CDVLVVGAGPAGFMAALTLARY-NINVRIIDAR 39
                7********************9.9***999875 PP

>> Pyr_redox_3  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0   3.1e-06    0.0033     166     233 ..       9      74 ..       7      91 .. 0.84

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 3.1e-06
  Pyr_redox_3 166 kvvViGgknSavDaAlelvrkgaeVtvvtrgseiekeesdpsyslkpdienrleelvkeekikvlfna 233
                  +v+V+G++  ++ aAl l+r++ +V++++ + e  + ++     ++p++++ l++l  ++++++  n+
   EEA22949.1   9 DVLVVGAGPAGFMAALTLARYNINVRIIDARPE--RIQTGHAGGVQPRTQEILQTLNLRHRLDIQGNH 74 
                  689999999999999999999999999999985..555668889999999999999888888887774 PP

>> Trp_halogenase  Tryptophan halogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   3.4e-06    0.0036       1      59 [.       9      65 ..       9      81 .. 0.74

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 3.4e-06
                    EEEEE--SHHHHHHHHHHHHHTTTSSEEEEEE-SSS---SS-E..E--THHHHTHHHHT-- CS
  Trp_halogenase  1 kivivGGGtaGwlaAaalakalkgklevtlveseeigtvgvGe..atipsirkllrlLgid 59
                    ++++vG+G+aG++aA +la++    ++v ++++    +++ G   +  p ++++l+ L++ 
      EEA22949.1  9 DVLVVGAGPAGFMAALTLARYN---INVRIIDAR-PERIQTGHagGVQPRTQEILQTLNLR 65
                    699******************9...777777653.23444444224567777777777665 PP

>> Pyr_redox  Pyridine nucleotide-disulphide oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.6   0.0   3.6e-05     0.038       2      33 ..      10      41 ..       9      77 .. 0.88

  Alignments for each domain:
  == domain 1  score: 14.6 bits;  conditional E-value: 3.6e-05
                EEEECSSHHHHHHHHHHHHTTSEEEEEESSSS CS
   Pyr_redox  2 vvvvGgGyiglElAgalaelgkkVtvversdk 33
                v+vvG+G  g ++A +la+++ +V +++++++
  EEA22949.1 10 VLVVGAGPAGFMAALTLARYNINVRIIDARPE 41
                89**************************9987 PP

>> TrkA_N  TrkA-N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0    0.0001      0.11       1      41 [.      10      50 ..      10      64 .. 0.89

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 0.0001
                EEEES-SHHHHHHHHHHHHTTEEEEEEESSHHHHHHHHHTT CS
      TrkA_N  1 iiiiGlGrvGrslaeeLseggkdvvvidkdeerveelreeg 41
                ++++G+G  G   a +L +++++v +id ++er+++  + g
  EEA22949.1 10 VLVVGAGPAGFMAALTLARYNINVRIIDARPERIQTGHAGG 50
                68*****************9989***********9866655 PP

>> 3HCDH_N  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00023      0.24       2      40 ..      10      48 ..       9      73 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00023
                EEEE--SCCHHHHHHHHHHTT-EEEEE-S-HHHHHHHHH CS
     3HCDH_N  2 vaviGaGtmGagiaavfasagleVvlvdiseealekale 40
                v v+GaG  G   a  +a+ +++V+++d ++e+++++++
  EEA22949.1 10 VLVVGAGPAGFMAALTLARYNINVRIIDARPERIQTGHA 48
                78******************************9998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (612 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       388  (0.0216409); expected 358.6 (0.02)
Passed bias filter:                      367  (0.0204696); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              17  [number of targets reported over threshold]
# CPU time: 0.58u 0.25s 00:00:00.83 Elapsed: 00:00:00.40
# Mc/sec: 4560.27
//
Query:       EEA22950.1  [L=265]
Description: versicolorin reductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      2e-54  184.7   1.1    3.4e-54  183.9   1.1    1.3  1  adh_short_C2    Enoyl-(Acyl carrier protein) reductase
    4.9e-47  159.9   1.3    6.5e-47  159.5   1.3    1.1  1  adh_short       short chain dehydrogenase
    1.9e-14   54.0   1.0      3e-14   53.3   1.0    1.2  1  KR              KR domain
  ------ inclusion threshold ------
      0.024   14.1   0.1      0.033   13.6   0.1    1.4  1  Epimerase       NAD dependent epimerase/dehydratase family
       0.12   12.3   0.9        0.2   11.5   0.9    1.4  1  NAD_binding_10  NAD(P)H-binding
       0.13   12.3   0.5       0.56   10.3   0.5    1.9  1  Shikimate_DH    Shikimate / quinate 5-dehydrogenase
       0.14   11.2   0.4       0.24   10.5   0.2    1.4  2  RmlD_sub_bind   RmlD substrate binding domain


Domain annotation for each model (and alignments):
>> adh_short_C2  Enoyl-(Acyl carrier protein) reductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  183.9   1.1   1.3e-57   3.4e-54       1     232 [.      16     262 ..      16     263 .. 0.91

  Alignments for each domain:
  == domain 1  score: 183.9 bits;  conditional E-value: 1.3e-57
                   TTTTSHHHHHHHHHHHTT-EEEEEESSGGH..HHHHHHHHHHTTSE..E.EE--TTSHHHHHHHHHHHHHHHSSEEEEEE-----EGCSS-GGGH-H CS
  adh_short_C2   1 GaasgIGraiAkalaeeGaevvltdlneea..kkrveelaeelgae..v.lecDVtdeeqvealveevvekfgklDilvnnagiapklkgpfletsr 92 
                   Ga +g+G+ iAk+la++Ga+vv+ +++  +  ++ v+e+++  g+   v +++DV+++++v++l+e++ ++fgk+Di+v n g+     +  +++++
    EEA22950.1  16 GAGRGLGASIAKELASHGASVVVNYAKSVGpaQALVDEIQALPGSPkaVaIQADVSKTAEVKRLFEDAIKTFGKIDIVVSNSGMEVF--SAEEDVTE 110
                   889************************99986677888887767555447************************************9..7889**** PP

                   HHHHHHHHHHTHHHHHHHHHHHHHCTSCCEEEEEEEGGGTSB.STTTTHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEE--BHCTG.GGGSTT... CS
  adh_short_C2  93 eefdraldvnlyslfllakaalplmkeggsivnlssvgaerv.vpnynaygaaKaalealtrylAvelgpkgiRvNavspgpikTla.asgikg... 184
                   e +d++++ n+++ f +a++al ++ egg+++ +ssv+a++  vpn++ y+ +K a+e++tr++Av++g+k+++vNa +pg i T++  ++  +   
    EEA22950.1 111 ELYDKVFALNTRAQFFVAQHALIHASEGGRLILTSSVAATMNgVPNHALYAGSKSAVEGFTRSFAVDCGKKRMTVNALAPGGILTDMyLENSWHyap 207
                   *************************************999766*******************************************97333332334 PP

                   .......HHHHHHHHHHHSTTSS-B-HHHHHHHHHHHCSGGGTT--SEEEEESTT CS
  adh_short_C2 185 .......fdelleelearaplgrlgtpeevaeaalfLasdeasyitGqtlvvDgG 232
                           +e+ + +++  plgr+g+p++va++++fL+sdea++++Gq++   gG
    EEA22950.1 208 ggkpgmpIEEINAGIASLCPLGRTGKPTDVARVVAFLCSDEAEWVNGQVIKLSGG 262
                   45555666789999*************************************9999 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  159.5   1.3   2.5e-50   6.5e-47       1     187 [.      10     198 ..      10     204 .. 0.97

  Alignments for each domain:
  == domain 1  score: 159.5 bits;  conditional E-value: 2.5e-50
                 SEEEEESTTSHHHHHHHHHHHHTT-EEEE.EESCHHHHHHHHHHHHHT..TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEEEE---SS--SSGGGC CS
   adh_short   1 kvvlvtGassGIGraiakelakeGakvvv.vdrseekleevakelkee..gakalaiqvDvtdreevealvekavkklgkldvLvnNAGitgsgpfsel 96 
                 k++l+tGa++G+G  iakela+ Ga+vvv +++s  +++++++e++++  + ka+aiq+Dv++ +ev++l+e+a+k +gk+d++v N G++ +++ +++
  EEA22950.1  10 KIALITGAGRGLGASIAKELASHGASVVVnYAKSVGPAQALVDEIQALpgSPKAVAIQADVSKTAEVKRLFEDAIKTFGKIDIVVSNSGMEVFSAEEDV 108
                 79***********************************************999*********************************************** PP

                 SHHHHHHHHHHHTHHHHHHHHHHHHHHHHCTTEEEEEEEEGGG.TSB-TTBHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEEESSBSSHHH CS
   adh_short  97 seeewervievNltgvflltravlpamlkqssGrIvnvsSvag.kvpvagvaaYsAsKaavagltrslakelaptgirvnavaPGlvdTdma 187
                 +ee +++v+++N  + f +++++l +  ++++Gr + +sSva+  ++v++ a Y+ sK av+g+trs+a +  +++ +vna+aPG++ Tdm 
  EEA22950.1 109 TEELYDKVFALNTRAQFFVAQHALIH--ASEGGRLILTSSVAAtMNGVPNHALYAGSKSAVEGFTRSFAVDCGKKRMTVNALAPGGILTDMY 198
                 ************************99..89***********996789*******************************************96 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.3   1.0   1.2e-17     3e-14       4     161 ..      13     172 ..      11     186 .. 0.88

  Alignments for each domain:
  == domain 1  score: 53.3 bits;  conditional E-value: 1.2e-17
                 EEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHT.T-.EEEE----TT-HHHHHHHHHHHHHHSS---EEEE---------TTT- CS
          KR   4 litGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaeleal.ga.evevvaaDvsdkdavealleeikaeeppikGvihaAgvlrdklleem 100
                 litG+  gLG ++a+ la++ga+ +v  ++s    + ++al++e++al g  +  +++aDvs+ ++v++l+e++ +++++i  v+   g+   ++ e++
  EEA22950.1  13 LITGAGRGLGASIAKELASHGASVVVNYAKSVG--P-AQALVDEIQALpGSpKAVAIQADVSKTAEVKRLFEDAIKTFGKIDIVVSNSGMEVFSAEEDV 108
                 9******************************44..4.45588888888644589999****************************************** PP

                 -HHHHHHHHTTTTHHHHHH..HHHTTTS--SEEEEEEEHHH.HH--TT-HHHHHHHHHHHHHHH CS
          KR 101 taedleqvlapKvkGawnL..helledesldffvlfSSiag.llgsagqanYaaaNaflDalae 161
                 t+e +++v+a   ++   +  h l++ ++   ++l+SS+a+ + g + +a Ya   + ++++ +
  EEA22950.1 109 TEELYDKVFALNTRAQFFVaqHALIHASEGGRLILTSSVAAtMNGVPNHALYAGSKSAVEGFTR 172
                 ********99888776554328889999***********9846699*******99999988876 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.1   1.3e-05     0.033       1      67 [.      12      83 ..      12     186 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 1.3e-05
                EEEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC.........EEEE--TT-HHHHHHHHHHHT-SE CS
   Epimerase  1 ilVtGatGfiGsalvkallekgyevigldrlssasntarledl.........elveldltdrsalerlfkeeqpda 67
                +l+tGa   +G+ ++k+l+++g  v++   +s + ++a+ +++           +++d+ + ++++rlf++    a
  EEA22950.1 12 ALITGAGRGLGASIAKELASHGASVVVNYAKSVGPAQALVDEIqalpgspkaVAIQADVSKTAEVKRLFED----A 83
                59**********************9999999999999999988********999*************9995....3 PP

>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.5   0.9   7.7e-05       0.2       1      69 [.      16     103 ..      16     172 .. 0.64

  Alignments for each domain:
  == domain 1  score: 11.5 bits;  conditional E-value: 7.7e-05
                     TTTSHHHHHHHHHHHHC-T-EEEEEETT.......HHHCHHHHCTTTCEEEE--TT-CCHHHHHHT.......T-SEEEES-.....- CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRn.......peklaeleaeeglevvegdvtdvedlaealk.......gadaVvsal.....g 69 
                     GA  + G  ++kel+++g   v+ ++ +        +++++l+ ++++ ++++dv++++++++ ++        +d+Vvs+      +
      EEA22950.1  16 GAGRGLGASIAKELASHGASVVVNYAKSvgpaqalVDEIQALPGSPKAVAIQADVSKTAEVKRLFEdaiktfgKIDIVVSNSgmevfS 103
                     788888999999999997444444555566333223455688899********************96666666669999988444442 PP

>> Shikimate_DH  Shikimate / quinate 5-dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.5   0.00022      0.56       9      58 ..       6      56 ..       2     119 .. 0.91

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00022
                  ..TT-EEEEES-SH.HHHHHHHHHHCCT-CEEEEEESSHHHHHHHHHHHT. CS
  Shikimate_DH  9 slkekkvlliGaGe.maelvakhLlakgvkkvvvaNRtlerakelaeelkg 58
                  +l++k +l+ GaG+ ++  +ak L+++g+  vv    ++  a++l++e+++
    EEA22950.1  6 DLQGKIALITGAGRgLGASIAKELASHGASVVVNYAKSVGPAQALVDEIQA 56
                  6888999******8689*************888888999999999999864 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.2   9.2e-05      0.24       4      89 ..      13     131 ..      10     147 .. 0.76
   2 ?   -3.9   0.0       2.2   5.7e+03     180     194 ..     231     245 ..     230     251 .. 0.72

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 9.2e-05
                    EEESTTSHHHHHHHHHCTTTSEEEEEE-TT........................T--TTSHHHHHHHHHHH.....--SEEEE------HHHHHHS CS
  RmlD_sub_bind   4 lvtGanGqlGseLakqlaeeglevlaltre........................eldltdaeavaellkea.....kpdvvvnaAAytavDkaEse 70 
                    l+tGa+  lG  +ak+la++g++v+    +                        ++d+++ ++v++l+++a     k d+vv+     +v+ aE++
     EEA22950.1  13 LITGAGRGLGASIAKELASHGASVVVNYAKsvgpaqalvdeiqalpgspkavaiQADVSKTAEVKRLFEDAiktfgKIDIVVSNSG-MEVFSAEED 107
                    89*******************99988855569************************************887333335567776553.345555444 PP

                    .....HHHHHHHHTHHHHHHHHHH CS
  RmlD_sub_bind  71 .....eeaayavnaeavealAeaa 89 
                          ++ +a+n +a   +A+ a
     EEA22950.1 108 vteelYDKVFALNTRAQFFVAQHA 131
                    211116778888999888888877 PP

  == domain 2  score: -3.9 bits;  conditional E-value: 2.2
                    EE--EEHHHHHHHHH CS
  RmlD_sub_bind 180 lgsPTsardlAevll 194
                    +g+PT ++++ ++l 
     EEA22950.1 231 TGKPTDVARVVAFLC 245
                    688998887777664 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (265 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       531  (0.0296168); expected 358.6 (0.02)
Passed bias filter:                      464  (0.0258799); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.45u 0.25s 00:00:00.70 Elapsed: 00:00:00.39
# Mc/sec: 2047.71
//
Query:       EEA22951.1  [L=880]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
     0.0038   16.3   2.1     0.0083   15.2   2.1    1.6  1  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   2.1   4.6e-07    0.0083       9     231 ..     308     545 ..     300     628 .. 0.74

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 4.6e-07
  Fungal_trans   9 hpqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspssslwilqsLlllelyek 105
                      f +   psf+p+   ++ +k  +   +lll+++a+Ga  ++s+++ + +         i+     eil  +dfs  ++   i+q+ lll +  +
    EEA22951.1 308 EKYFRLCPGPSFTPNEIFKQLPKHGKIAGILLLLMIAVGAAATPSIESHDFAIGVA----EICRLAFSEILE-RDFSITVE-PLISQCALLLLYLGM 398
                   44555555589999998899999999999******************999333333....677777777777.99999999.9************** PP

  Fungal_trans 106 tssdralher...hhgvavr.larslgLhrnpsyvgkks.....lwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLPcddddlw 193
                   + ++r l       +++ ++ +    +L + +  + +++      w + ++ +  r Rl ++  + D  ++l +  p+  + +++  p+P+dd  +w
    EEA22951.1 399 WAGERWLMGIssaQREMYIHlFHSATSLPKSEITEFPSDmnlhdQWSRLKD-QGFRSRLVYGWAMADQEWSLFYDKPNVVSVEMLVDPMPEDDT-VW 493
                   ***732222246655555555555555555555555555676656666666.888***********************999999999******9.** PP

  Fungal_trans 194 esddaseetlvetk.......lsneeksrkiasfllaLkkilsk.......i 231
                    +++a+e+  ++         ls + + + + +++l++++ +++       +
    EEA22951.1 494 KTSSAAEWATLGSGlpmsnerLSLRDFYHRFINGELRVSRETGSsqlslrlL 545
                   **********996688888887777777777777777777666655555550 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (880 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       332  (0.0185175); expected 358.6 (0.02)
Passed bias filter:                      274  (0.0152825); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.64u 0.26s 00:00:00.90 Elapsed: 00:00:00.42
# Mc/sec: 6272.67
//
Query:       EEA22952.1  [L=2142]
Description: polyketide synthase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.7e-78  263.7   0.0      4e-78  262.5   0.0    1.6  1  ketoacyl-synt    Beta-ketoacyl synthase, N-terminal domain
    4.8e-77  258.9   3.0    5.9e-76  255.4   0.2    3.1  3  SAT              Starter unit:ACP transacylase in aflatoxin b
    1.6e-43  149.4   0.0    1.5e-42  146.3   0.0    2.2  2  Acyl_transf_1    Acyl transferase domain
    3.5e-34  117.3   0.1    6.8e-34  116.4   0.1    1.5  1  Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
    1.7e-25   90.5   0.0    5.1e-25   88.9   0.0    1.8  1  Thioesterase     Thioesterase domain
    3.6e-21   75.3   6.9    1.8e-10   41.0   0.5    2.9  2  PP-binding       Phosphopantetheine attachment site
    1.1e-13   51.1   0.0    1.9e-13   50.3   0.0    1.4  1  PS-DH            Polyketide synthase dehydratase
    2.1e-05   24.0   0.0    4.3e-05   23.0   0.0    1.4  1  Thiolase_N       Thiolase, N-terminal domain
    0.00015   22.2   0.0    0.00038   20.9   0.0    1.7  1  KAsynt_C_assoc   Ketoacyl-synthetase C-terminal extension
  ------ inclusion threshold ------
       0.13   12.1   0.0       0.28   11.0   0.0    1.6  1  Abhydrolase_3    alpha/beta hydrolase fold
       0.14   11.4   0.0       0.51    9.6   0.0    2.0  2  Hydrolase_4      Serine aminopeptidase, S33


Domain annotation for each model (and alignments):
>> ketoacyl-synt  Beta-ketoacyl synthase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  262.5   0.0   2.4e-81     4e-78       4     253 .]     370     617 ..     368     617 .. 0.95

  Alignments for each domain:
  == domain 1  score: 262.5 bits;  conditional E-value: 2.4e-81
                    EEEEEEEEEBTTBSSHHHHHHHHHTT---EEES-TTSSCGTTSBTSSTTEEE-BSS.EEE..S.TTEGGTTSTHHHHHHHCTS-HHHHHHHHHHHH CS
  ketoacyl-synt   4 vaivGmgarfPggndveefwelLlegrdaiselpadrwdadklydpparaagkiktklggfld.vddfdpeffgispreaeamdpqqrllleaawe 98 
                    +aivGm++rfP++ d+e++w+lL +g d  + +p dr+da ++ dp+ +  +k++t++g+f++ ++ fdp+ff++sprea+++dp+qrl++++a+e
     EEA22952.1 370 IAIVGMAGRFPNSADHEAYWDLLSQGLDVHRVIPPDRFDAAAHTDPSGNGRNKSHTPYGCFIEdAALFDPRFFSMSPREAKQTDPMQRLAIVTAYE 465
                    9*********************************************************************************************** PP

                    HHHHHTS-HHTCTTGG...EEEEEEESSTHHHHHHHHHHHTTGGGSCTTHHHHHSTTHHHHHHHHHHT--SSEEEEESGGGHHHHHHHHHHHHHHT CS
  ketoacyl-synt  99 aledagltpeeldgsr...vgvfiGvgagdyaalaaldedgsevkaspkavgavlanviagrisyalglrGpsvtvdtACsSslvavhaavqslrs 191
                    a+e+ag+  +++ +++   +g f G ++ d+++++a +    + ++++ ++g  ++++ +gri+y++g+ Gps+++dtACsSs++a+++a+ slr+
     EEA22952.1 466 AMESAGFVMNRTPSTQanrIGTFYGQTSDDWREINAAE----NIDTYF-ITGG-VRAFGPGRINYHFGFSGPSFSIDTACSSSFAAIQLACTSLRA 555
                    *******9999854444458888888888886644444....688999.***9.****************************************** PP

                    TS-SEEEEEEEE---SHHHHHHHHHTTBB-TTSGGGTTBTTB-SB-BB-EEEEEEEEECHHH CS
  ketoacyl-synt 192 geadvalaGGvellltpeavagfsaagllspdgrckafdpkadGfvlGEGvGavvLkrleda 253
                    g++d+++aGG++ l++p  +ag+s+ ++ls++g ck+fd++adG+++GEGv++v+Lkr eda
     EEA22952.1 556 GDCDTVFAGGMNILTNPDIFAGLSKGQFLSKTGSCKTFDNDADGYCRGEGVATVILKRIEDA 617
                    **********************************************************9997 PP

>> SAT  Starter unit:ACP transacylase in aflatoxin biosynthesis
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  255.4   0.2   3.6e-79   5.9e-76       1     240 []       4     241 ..       4     241 .. 0.98
   2 ?   -1.6   0.0       1.1   1.8e+03      67     118 ..     953     998 ..     921    1025 .. 0.78
   3 ?    2.3   0.0     0.074   1.2e+02     188     235 ..    1044    1093 ..    1033    1098 .. 0.81

  Alignments for each domain:
  == domain 1  score: 255.4 bits;  conditional E-value: 3.6e-79
         SAT   1 llFGDqtadvlpeLrkLlqakenplLrsFLekasealraeisrlpaaerkslprftslqellerysesglkspalssallciaqlaqfivyleenpeey 99 
                 l++GDqt+dv+p+L++L+++k +plL++FLe+++ +l++ei rl+++er  +p+f+sl+ l+++y+++  + + l+sal+c+aqla+fi  +eenp+ y
  EEA22952.1   4 LIYGDQTVDVCPFLDHLFKKKRTPLLQNFLERSKIVLQDEICRLSRTERVGIPQFSSLRGLVDEYQRRCPRVASLESALTCLAQLAHFIGLAEENPQYY 102
                 689************************************************************************************************ PP

         SAT 100 pspestylvGlCtGllaAaavacskslseLvplaveavrvafrlGlevarvaarleegsssssesWslavtglseeelekalaefneekglppasrvyi 198
                  ++  +++vG+C+Gll+A+a+acs+sl  L+plave+vr+afrlG++v r+a+  e +  ++s+sW+ +vtg++ +++++a+++fn+++ l++a+++y+
  EEA22952.1 103 IKK-GSHIVGVCIGLLSASAIACSHSLVHLIPLAVETVRTAFRLGSCVGRMARLQE-PVVHESKSWTSLVTGVDLQAVASAIHAFNRTQRLQNANKLYV 199
                 *86.559********************************************99999.999*************************************** PP

         SAT 199 savssssvtisGpPstleallksskakkkkkksklpiyapyH 240
                 sav+s+s+++sGpPs+  +++++ k +++ +++ lpiy+pyH
  EEA22952.1 200 SAVASNSTAVSGPPSVHGNFWEQFKKTQSFNHRDLPIYGPYH 241
                 ****************************************** PP

  == domain 2  score: -1.6 bits;  conditional E-value: 1.1
         SAT  67 esglkspalssallciaqlaqfivyleenpeeypspestylvGlCtGllaAa 118
                 ++ +ksp++s + ++ +q+a +  +   +   +    ++ +vG++ G  aA 
  EEA22952.1 953 DALQKSPVVSQVATTCLQIALVDLWK--SWGVV----PSAVVGHSLGEYAAL 998
                 45678999999999999999876663..33333....457999999988875 PP

  == domain 3  score: 2.3 bits;  conditional E-value: 0.074
         SAT  188 kglppasrvyisavssss.vtisGpPstleallksskakkkkkks.klpi 235 
                   +++++s v i++++s+  ++++Gp +++e++ ++ +ak++  ++ kl++
  EEA22952.1 1044 LDITSTSEVEIACINSPIeTVLAGPSDAIEEVSTRLAAKRSDLQViKLKV 1093
                  567889**********999**********999999999888777545444 PP

>> Acyl_transf_1  Acyl transferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.2   0.0      0.25   4.1e+02     128     253 ..     178     302 ..     159     311 .. 0.74
   2 !  146.3   0.0     9e-46   1.5e-42       1     274 [.     900    1186 ..     900    1222 .. 0.82

  Alignments for each domain:
  == domain 1  score: 0.2 bits;  conditional E-value: 0.25
                    ECCEECS.HHHHHHH..TT.EEEEEEECCCCECCEEHHHHHHHHHHHHHCC..CCEEECCCEECTTCCC.CCCCCHHHHHHHHCCCHHCHHTTBEH CS
  Acyl_transf_1 128 dmaavelaeeeeklrcqddvvgavansprrvvisgsqealrelvervskeg.vgalvenvnvavhspqv.daiadalasaladiaprkpkvakiss 221
                     + a+   + +++l+  +++++++++s  ++++sg++    ++ e+ +k + +  ++  +    h p +  +++d+l+++++ +  ++ ++     
     EEA22952.1 178 VASAIHAFNRTQRLQNANKLYVSAVASN-STAVSGPPSVHGNFWEQFKKTQsFNHRDLPIYGPYHAPHLfTNVEDVLSEETLLLLDNFNQIRPV-- 270
                    444444567788888999*******996.67999***999999999999997888888888888887642788888999888888888776654.. PP

                    CCCHHHHHHCHHHHHHHHHHHCHCCHCCHHTT CS
  Acyl_transf_1 222 tsldesserelsaeywvanlrspvrfaeavls 253
                    +++  s+ rel++    ++l++ v  + +v+s
     EEA22952.1 271 LEFTYSTSRELFEHSIGQILQESVDWNTLVKS 302
                    45566667777777777777777777776666 PP

  == domain 2  score: 146.3 bits;  conditional E-value: 9e-46
                     EEEE--TT---TTTTCCHHHC-HHHHHHHHHHHHHCCHHHT--HHHHHHS--TTGG.GSHHHHHHHHHHHHHHHHHHHHHTT-TTSEEEE-TTH CS
  Acyl_transf_1    1 vfvfsGqGsQwaGMGmeLlktskafaaviaradeafksqygfsvldvlrnnpegll.daiqfvqpaLaavqialaellkskGvrpaavvGHSlG 93  
                     vf f+GqG+Q   MG  L+++s+ f++ +  +d+ + s+   s l +++   e  l ++ +++q+a + +qial++l+ks Gv p avvGHSlG
     EEA22952.1  900 VFMFTGQGAQYSTMGKRLFEESESFRKQLIHLDQIVLSEGLPSFLGAIDGSSEDALqKSPVVSQVATTCLQIALVDLWKSWGVVPSAVVGHSLG 993 
                     7************************************95555999999877665551567889******************************* PP

                     HHHHHHHCCSSSHHHHHHHHHHHHHHHHHHT..S-EECCEECS....HHHHHHH..TT.EEEEEEECCCCECCEEHHHHHHHHHHHHHCC...C CS
  Acyl_transf_1   94 ElAaavvagalsseeallavvlrsrlmmqla..gpgdmaavel...aeeeeklrcqddvvgavansprrvvisgsqealrelvervskeg..vg 180 
                     E+Aa++ ag ls+ +a+l v++r  l  +l       m+av+    + e + +  + +v  a+ nsp ++v++g+++a++e+ +r++++   ++
     EEA22952.1  994 EYAALYGAGILSQVDAVLLVARRAYLLESLCtmNSHTMLAVKGlmsSDELLDITSTSEVEIACINSPIETVLAGPSDAIEEVSTRLAAKRsdLQ 1087
                     *************************9999976566789999877734444455599******************************98773466 PP

                     CEEECCCEECTTCCCCCCCCHHHHHHHHCCCHHCHHTTBEHCCCHHH.HHHCHHHHHHHHHHHCHCCHCCHHTTS....SSECC-CCEECSSSS CS
  Acyl_transf_1  181 alvenvnvavhspqvdaiadalasaladiaprkpkvakisstsldes.serelsaeywvanlrspvrfaeavlsa....aetiplvfveispHs 269 
                     + + +v +a+hs+qv++i ++  +  ++++ ++p+v+  s   +     +++++a y ++  r++v f  a+       + t  +  +e+ pH+
     EEA22952.1 1088 VIKLKVPFAFHSAQVEPILEEFEKLAQSVVFHPPQVPVLSPCLSTTIdRPNVVDASYLRRHCRNTVDFIGAINTGidsgVVTRDDLWLELGPHP 1181
                     66778999**********99866655556666666666554433333268899***************99998872333445567789999999 PP

                     CCHCC CS
  Acyl_transf_1  270 lllaa 274 
                     +  + 
     EEA22952.1 1182 VCSNL 1186
                     87655 PP

>> Ketoacyl-synt_C  Beta-ketoacyl synthase, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  116.4   0.1   4.2e-37   6.8e-34       1     117 [.     625     746 ..     625     747 .. 0.97

  Alignments for each domain:
  == domain 1  score: 116.4 bits;  conditional E-value: 4.2e-37
                      SEEEEEEEEEE--STSSSTSTTHHHHHHHHHHHHHHHT--GGGEEEEE-SS-SSHHHHHHHHHHHHHHHGGGGG.....SCTSEEE-THHHH-B CS
  Ketoacyl-synt_C   1 yavikgsavnsdgahnsltapngeaqaraiekalaeagvdpedvdyveahgtgtplgDpiElealkkvfgekar.....kqplavgSvKsniGH 89 
                      ++vi+g+a+n+++++ s+t+p++ aq+ + +++++++ vdp+ vdyve+hgtgt++gD iE++++++vf+ ++      +qpl++gS K+niGH
       EEA22952.1 625 LGVIRGTATNHSAEAVSITHPHAGAQQFLFQNIMDDLAVDPRLVDYVEMHGTGTQAGDGIEIQSVTDVFAPRGArrraaNQPLFIGSAKANIGH 718
                      589********99********************************************************99888889999************** PP

                      -GGGHHHHHHHHHHHHHHHTEE--BTT- CS
  Ketoacyl-synt_C  90 leaAaGvaelikvvlalkhgvipptlnl 117
                      +ea +Gv +lik++l+++++ ipp++++
       EEA22952.1 719 GEAVSGVSALIKSLLMFQKNLIPPHCGI 746
                      ************************9876 PP

>> Thioesterase  Thioesterase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   88.9   0.0   3.2e-28   5.1e-25       1     217 [.    1891    2123 ..    1891    2134 .. 0.78

  Alignments for each domain:
  == domain 1  score: 88.9 bits;  conditional E-value: 3.2e-28
                    EEEEEE--TTCCSGGGHHHHHHCTTCEEEEEEECSTTSTSHHHCTTCHHHHHHHHHHHHHHH-SSSSEEEEEETHHHHHHHHHHHHHHHCT-SEE CS
  Thioesterase    1 rpLflfppagGsasvfrslasklsdpvvevlavqlpgrerdepplesieelaaeyaealrqiqpegPyalfGhSlGgllAfevArqLesqGlavk 95  
                    r+Lf++p++ G+a +++ +    +++  +v+++  p   +++++  +  ++   y++a++++qpegPy l+G+S+Gg lA+e++rqL ++G++v 
    EEA22952.1 1891 RKLFVLPDGSGAAFSYAAIPPLDDET--VVYGLNCPFMRTPDEFTIGVPAVTKIYIDAIKTRQPEGPYLLAGWSAGGVLAYEMTRQLIQRGEKVE 1983
                    58******************988887..888888888778******************************************************* PP

                    EEEEESCCCCCCHHCHHCCCHTTHHTHHHHHCCTTHHHCCTTTHCCHHHHHHHHHHHHHHHHHTCCS.......-TTSCSE.....HHCEEEEEE CS
  Thioesterase   96 slflidssapseteaqeasrraedeefveeltdlggtepeelledeellsellpalradyraleqys.......lrpeaaq.....klratlfng 178 
                     l+lids++p           +++ ++ +++  + g + +   + +   s llp +ra +r l+ ys       +  ++++     ++r  +   
    EEA22952.1 1984 NLILIDSPYPIK--------LEALPPVFHQFCNEIGLLGDGKSKPP---SWLLPHFRATVRELTAYSeilesteIDTSDMPpttliWARDGVVKN 2067
                    **********66........33333455555444444344455555...5666666666777777766655444333333366666999999999 PP

                    GSS-CTCCCCCCCHCH................CHCTC.ESCEEEEEESSHCCHHHS CS
  Thioesterase  179 sddklkdldtlelaer................weqkt.sgevsvhvlegdhfylle 217 
                    + d++ +++   +  +                w+  + +g+++   ++g+hf+++ 
    EEA22952.1 2068 PGDPKPTWEEGVRMPNsmewlvknrynlgdngWKLLVgKGKTRCVSMDGNHFTMMR 2123
                    99999999944444448999999999999999998772578889999******997 PP

>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.3   0.3   1.6e-12   2.6e-09       4      67 .]    1655    1718 ..    1652    1718 .. 0.95
   2 !   41.0   0.5   1.1e-13   1.8e-10       3      63 ..    1765    1825 ..    1764    1827 .. 0.97

  Alignments for each domain:
  == domain 1  score: 37.3 bits;  conditional E-value: 1.6e-12
  PP-binding    4 relvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlaelaayl 67  
                  ++++ + +g++ +e++++  + dlG+DSl+++++ ++l+ee+++++  + + ++ ++++l ayl
  EEA22952.1 1655 LDILVSEIGCSMSELNDNVEFEDLGVDSLMSLSISSRLREELDIAVGGTLFIDYGSVGQLKAYL 1718
                  57889999****************************************************9986 PP

  == domain 2  score: 41.0 bits;  conditional E-value: 1.1e-13
  PP-binding    3 lrelvaevlgvpleeidpdtdlfdlGlDSllavellaaleeefgveiplsdlfehptlael 63  
                  +r+ +ae +g++  ei+++ dl+  G+DSl+++++l+ l+e+ g+ +p++ l e++t++++
  EEA22952.1 1765 IRSTIAEEMGMDILEIHDSLDLSQIGMDSLMSLSILGTLREKTGTVFPPDFLIENTTIEQI 1825
                  899*******************************************************986 PP

>> PS-DH  Polyketide synthase dehydratase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.3   0.0   1.2e-16   1.9e-13       7     293 ..    1292    1590 ..    1287    1593 .. 0.80

  Alignments for each domain:
  == domain 1  score: 50.3 bits;  conditional E-value: 1.2e-16
                  EE--.-SS-EEEEEEE-.S-SS.TTTSEEETTEEB--TTHHHHHHHH....HHHHTS---.-EEEE..EEEE----.B--SS.-EEEEEEEEE-TTS CS
       PS-DH    7 rvrsasdkevvfrnrlr.laelpwLrDHrvdgkvvlPgagylemale....Aarqltgeskavelr..dvsilkalvlpede.pvevqlslepeedg 95  
                  ++  a++  v+ +++l+ ++    +  H+v+g +++P      ma      A ++l+++++ + ++  + + +++l+l+ ++ +  +q+ +e  +++
  EEA22952.1 1292 EIVDANSAVVTAEADLHdPHLKAIITGHKVGGAPLFPSSINADMAYTlskyAFERLHPGTEEFDVNicNMQSSSPLILDMTRkSQILQIKAEIVGNE 1388
                  555555666666666665566667899******************962233666666777777777669999*******999899999999999665 PP

                  -E....EEEEEEE-SS-TT.EEEEEEEEEE-----.......--B--HHHHHHHS-SEE....E-HHHHHHHHHHHSEEE-GGG--EEEEEEETTEE CS
       PS-DH   96 adrawvefeifSregggeewtehatGtvrlaegaa.......aaavdlealqarcaepaslrsvssaefYerlaargleyGpsFqglralwrgdgea 185 
                  ++   ++++  S ++g+   t+ a+  v ++  +        +a +  + +++ +a+ as+ ++     Y+ + ++ ++y ++F+g+++++ +    
  EEA22952.1 1389 KQ---AKITFQSKQDGKP-VTKYAECVVYFEDPKMwaaefkrSAYLVNARIRTLQAPNASIHKIHRGMAYKLF-SALVDYSDTFRGMEEVRLDSENL 1480
                  55...7888889999987.799999999988766699988765555555667788888888999999999999.999***************97777 PP

                  EEEE---GGGSSTTTT-SB-HHHHHHHHHHG..GG..----------EEEEEEEEEEE-S...-BTS--EEEEEE..----SS-EEEEEEEE-SS-B CS
       PS-DH  186 laelrlpeelaggesayvlhPallDaalQllaaal..saeaekadaaylPvaierlrvyrpssaageelwvharl..eeegarsivadltlvdedGr 278 
                  +a +r++  ++++++ +++ P+ +D   ++ +  +  +++ ++++++y+  ++e++r+ r +++ ++e ++++++   +e+ +++++d+ ++ e  +
  EEA22952.1 1481 EAIARIKFRTSSKDGTFLFNPYFIDNTCHISGFIMnaTDAVDSTNQVYISHGWETMRFVR-KPSIDKEYYSYVKMsfVSEHSTMVSGDVYVL-EGTE 1575
                  7777777666666777*************7777778988899*****************6.6668999*******99888889*******99.4566 PP

                  EEEEEESEEEEE--X CS
       PS-DH  279 vvaeieglrlrrver 293 
                  ++  + g+r++ v+r
  EEA22952.1 1576 IIGVFGGVRFQGVPR 1590
                  666677777776665 PP

>> Thiolase_N  Thiolase, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.0   0.0   2.6e-08   4.3e-05      77     119 ..     531     573 ..     522     587 .. 0.90

  Alignments for each domain:
  == domain 1  score: 23.0 bits;  conditional E-value: 2.6e-08
                 EEEEEEHGGGHHHHHHHHHHHHHHTTSHSEEEEEEEEESTTS- CS
  Thiolase_N  77 pavtvnkvcsSglkavalaaqsiaageadvvvagGvEsmsnap 119
                 p+  ++ +csS+++a+ la+ s++ag++d v agG+  ++n +
  EEA22952.1 531 PSFSIDTACSSSFAAIQLACTSLRAGDCDTVFAGGMNILTNPD 573
                 7789********************************9999865 PP

>> KAsynt_C_assoc  Ketoacyl-synthetase C-terminal extension
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.0   2.3e-07   0.00038      14     108 ..     764     864 ..     756     869 .. 0.79

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 2.3e-07
  KAsynt_C_assoc  14 kVvteptpwpggi......vgvNsfGfGGsnvHviLksnkkekrkeeskeeslprLlvlsgrteeaveallekleehlldaellsllneilseei 102
                     ++ t+ tp+p         + +N f+  G n+ ++L+ ++ +  + +++  ++ +++++s+++ ++ + +l++l ++ + ++++ l + ++++  
      EEA22952.1 764 NIATRLTPFPVPQetrkklIFINNFSAAGGNSAMLLEDAPDRVISGKDN--RRFNVVTVSAKSLASFQGNLARLLSWVEGNTEIGLSDLAYTTTA 856
                     5555555554333336677*********************999998888..9*************************999999998777666555 PP

  KAsynt_C_assoc 103 sr..lpyR 108
                     +r  + yR
      EEA22952.1 857 RRqhFIYR 864
                     54436666 PP

>> Abhydrolase_3  alpha/beta hydrolase fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0   0.00017      0.28      65     106 ..    1948    1988 ..    1917    2066 .. 0.70

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 0.00017
                     HHTETTCEEEEEEETHHHHHHHHHHHHHHHTT---EEEEEEE CS
  Abhydrolase_3   65 elgadpsrivlaGdSaGGnlaaavalrardegepkvagqvli 106 
                     + +  +    laG SaGG la+ +++++ ++g  kv+ ++li
     EEA22952.1 1948 KTRQPEGPYLLAGWSAGGVLAYEMTRQLIQRG-EKVENLILI 1988
                     55555667789*******************96.567777776 PP

>> Hydrolase_4  Serine aminopeptidase, S33
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.0       2.2   3.7e+03      75      91 ..     982     998 ..     973    1014 .. 0.68
   2 ?    9.6   0.0   0.00031      0.51      65     115 ..    1943    1996 ..    1939    2041 .. 0.83

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 2.2
  Hydrolase_4  75 elplfllGhSmGGlial 91 
                    p  ++GhS+G + al
   EEA22952.1 982 VVPSAVVGHSLGEYAAL 998
                  56899******966554 PP

  == domain 2  score: 9.6 bits;  conditional E-value: 0.00031
  Hydrolase_4   65 fvekvkeehpelplfllGhSmGGliallyl...lrypdkvaglilsaPalkika 115 
                   +++++k+++pe p  l G S GG++a +++    ++ +kv+ lil+ + + ik 
   EEA22952.1 1943 YIDAIKTRQPEGPYLLAGWSAGGVLAYEMTrqlIQRGEKVENLILIDSPYPIKL 1996
                   6899************************99877667778999999866666654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (2142 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       533  (0.0297284); expected 358.6 (0.02)
Passed bias filter:                      508  (0.028334); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 1.15u 0.33s 00:00:01.48 Elapsed: 00:00:00.55
# Mc/sec: 11774.16
//
Query:       EEA22953.1  [L=646]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    4.2e-11   43.2   0.6        2.4    9.2   0.0    6.7  7  WD40         WD domain, G-beta repeat
    0.00018   21.7   0.0         18    5.7   0.0    4.1  4  ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
  ------ inclusion threshold ------
        1.5    8.2   7.1        2.2    7.6   7.1    1.2  1  SDA1         SDA1
        5.5    5.1   7.6        7.9    4.5   7.6    1.1  1  Nop14        Nop14-like family


Domain annotation for each model (and alignments):
>> WD40  WD domain, G-beta repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.7   0.0    0.0016       7.1      12      36 ..     108     132 ..      99     134 .. 0.83
   2 !    5.3   0.0    0.0089        40      11      36 ..     176     201 ..     169     201 .. 0.88
   3 !    7.5   0.0    0.0018       8.3       6      38 .]     214     247 ..     209     247 .. 0.69
   4 ?   -1.7   0.1       1.4   6.5e+03      20      38 .]     456     473 ..     450     473 .. 0.78
   5 !    9.2   0.0   0.00053       2.4      17      34 ..     496     513 ..     484     514 .. 0.85
   6 ?    4.0   0.0     0.023     1e+02       9      38 .]     536     562 ..     524     562 .. 0.79
   7 ?   -1.3   0.0       1.1     5e+03       6      28 ..     577     601 ..     573     605 .. 0.64

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0016
                 SEEEEEEETTSSEEEEEETTSEEEE CS
        WD40  12 svtslafspdgawlasGsdDgtvri 36 
                 s++ +    d +w+++G+ Dg +r 
  EEA22953.1 108 SINTVTSTADMRWVFTGGSDGYIRK 132
                 58888889999******88****95 PP

  == domain 2  score: 5.3 bits;  conditional E-value: 0.0089
                 SSEEEEEEETTSSEEEEEETTSEEEE CS
        WD40  11 ssvtslafspdgawlasGsdDgtvri 36 
                 s+v+sla +++g wl+sG + g++r+
  EEA22953.1 176 SPVYSLAAQREGLWLLSGLESGSIRL 201
                 5799**************89999997 PP

  == domain 3  score: 7.5 bits;  conditional E-value: 0.0018
                 EEESS.SSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   6 tltGH.ssvtslafspdgawlasGsdDgtvriWd 38 
                  l+ H s v+ l   +d + l+sGs+D+ v  Wd
  EEA22953.1 214 LLKNHtSAVSVLNLMSDEQSLLSGSWDKRVLEWD 247
                 57788666755554555666679*******9998 PP

  == domain 4  score: -1.7 bits;  conditional E-value: 1.4
                 TTSSEEEEEETTSEEEEEE CS
        WD40  20 pdgawlasGsdDgtvriWd 38 
                 +d ++la +s Dg + iWd
  EEA22953.1 456 SDTTFLA-ASIDGPISIWD 473
                 5667776.79999899998 PP

  == domain 5  score: 9.2 bits;  conditional E-value: 0.00053
                 EEETTSSEEEEEETTSEE CS
        WD40  17 afspdgawlasGsdDgtv 34 
                 ++spdg+++ +G ++gtv
  EEA22953.1 496 CWSPDGNYIYAGRRNGTV 513
                 5***********99**98 PP

  == domain 6  score: 4.0 bits;  conditional E-value: 0.023
                 SSSSEEEEEEETTSSEEEEEETTSEEEEEE CS
        WD40   9 GHssvtslafspdgawlasGsdDgtvriWd 38 
                 G   vt+l+  p+g+ l+++s    +r++d
  EEA22953.1 536 GA--VTALKAMPNGRHLLCAS-HDILRLYD 562
                 43..9*************999.77777665 PP

  == domain 7  score: -1.3 bits;  conditional E-value: 1.1
                 EEESS.SS.EEEEEEETTSSEEEEE CS
        WD40   6 tltGH.ss.vtslafspdgawlasG 28 
                 ++ GH ++ ++ l +++  ++++s+
  EEA22953.1 577 VIPGHrTGvISQLFVDSTCRYMLSA 601
                 5679988844666566666666555 PP

>> ANAPC4_WD40  Anaphase-promoting complex subunit 4 WD40 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.6   0.0    0.0092        41      40      88 ..     177     226 ..     166     230 .. 0.81
   2 ?    2.5   0.1      0.04   1.8e+02      28      87 ..     211     267 ..     201     270 .. 0.85
   3 !    5.7   0.0    0.0041        18      45      70 ..     496     521 ..     491     524 .. 0.91
   4 !    5.2   0.0    0.0059        26      27      74 ..     526     570 ..     522     574 .. 0.83

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.0092
  ANAPC4_WD40  40 evrsLaWkpdgklLavaysdgevrllda..esgkvvhslsvksekavtclg 88 
                   v sLa + +g  L  + + g++rl ++  e+gk +  l+ +++ av+ l+
   EEA22953.1 177 PVYSLAAQREGLWLLSGLESGSIRLQSVrhEEGKEIALLKNHTS-AVSVLN 226
                  68899999****************99874467888888887777.577776 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.04
  ANAPC4_WD40  28 rvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvhslsvksekavtcl 87 
                  ++  l  +++ s v+ L+   d++ L  +  d +v   d + gkv +s++ ++++ ++ +
   EEA22953.1 211 EIALL--KNHTSAVSVLNLMSDEQSLLSGSWDKRVLEWDLNVGKVKNSFRSGASQ-ISAI 267
                  55555..789999************************************999885.7766 PP

  == domain 3  score: 5.7 bits;  conditional E-value: 0.0041
  ANAPC4_WD40  45 aWkpdgklLavaysdgevrlldaesg 70 
                  +W+pdg+ +  +  +g+v+ ++ ++g
   EEA22953.1 496 CWSPDGNYIYAGRRNGTVEEYSLHKG 521
                  8*****************99998876 PP

  == domain 4  score: 5.2 bits;  conditional E-value: 0.0059
  ANAPC4_WD40  27 qrvwtleedkedsevrsLaWkpdgklLavaysdgevrlldaesgkvvh 74 
                  +rv++l  ++ ++ v++L+  p+g+ L  a +d  +rl+d +++   h
   EEA22953.1 526 ERVFKL--PTVGGAVTALKAMPNGRHLLCASHD-ILRLYDLKEEAYKH 570
                  799999..899**************99988665.78998887766555 PP

>> SDA1  SDA1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   7.1    0.0005       2.2     108     171 ..       7      65 ..       2     111 .. 0.51

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0005
        SDA1 108 sdddseedseggwidvesdeeeieesdesedeeeeeeeeeekeekeeeeeeeeeeeeeeeeeee 171
                 +ddd   d  g+  d +sd+e++++ d ++ + ++e+++e++++ ++ +++   +++e     +
  EEA22953.1   7 EDDD--RDIAGS-QDGSSDNEDEQMRDVDDGDGDNEQDQEQEQDGDSPSNNS--QTSEGAGGVS 65 
                 2111..233222.444455555555554444444433333333322222222..2222222222 PP

>> Nop14  Nop14-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   7.6    0.0018       7.9     351     411 ..       7      61 ..       2     106 .. 0.40

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.0018
       Nop14 351 deddfeedddlveseseeeeeeeeedeeeeedeeeeeeeeededdlsdlese.eeeeedele 411
                 ++dd ++  +++ s+++e+e+  + d+ +        ++e+d+++++d +s  ++++ +e  
  EEA22953.1   7 EDDDRDIAGSQDGSSDNEDEQMRDVDDGDG-------DNEQDQEQEQDGDSPsNNSQTSEGA 61 
                 222222222122222221111111111111.......1111111111111111222222221 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (646 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       676  (0.0377043); expected 358.6 (0.02)
Passed bias filter:                      471  (0.0262703); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.67u 0.31s 00:00:00.98 Elapsed: 00:00:00.48
# Mc/sec: 4070.86
//
Query:       EEA22954.1  [L=768]
Description: Pumilio-family RNA binding repeat domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.7e-36  120.8   1.0      6e-06   25.7   0.0    8.9  9  PUF            Pumilio-family RNA binding repeat
  ------ inclusion threshold ------
          7    6.9   6.5        5.4    7.3   0.9    2.5  2  zf-C2H2_assoc  Unstructured conserved, between two C2H2-type 


Domain annotation for each model (and alignments):
>> PUF  Pumilio-family RNA binding repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.1     0.049   4.4e+02      12      33 ..     406     427 ..     403     429 .. 0.78
   2 !   24.2   0.0     2e-09   1.8e-05       8      31 ..     438     461 ..     432     464 .. 0.90
   3 !   25.7   0.0   6.7e-10     6e-06       1      30 [.     467     495 ..     467     500 .. 0.88
   4 !    5.5   0.0    0.0017        15      11      24 ..     513     526 ..     507     529 .. 0.91
   5 !    9.9   0.0   6.6e-05      0.59       8      32 ..     550     574 ..     544     575 .. 0.83
   6 !   11.5   0.0   2.1e-05      0.18       4      28 ..     582     606 ..     579     613 .. 0.79
   7 !   14.5   0.0   2.4e-06     0.022      10      34 ..     624     648 ..     621     649 .. 0.84
   8 !   16.0   0.0   7.7e-07    0.0069       8      32 ..     666     690 ..     664     692 .. 0.81
   9 ?   -2.0   0.0       0.4   3.6e+03       3      18 ..     697     712 ..     696     712 .. 0.76

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.049
                 STTHHHHHHHHHHHSCHHHHHH CS
         PUF  12 dqyGnyvvQkllehateeqkkl 33 
                 dq ++ ++Q+ l++ t eqk +
  EEA22954.1 406 DQQASIFLQQKLKVGTVEQKYD 427
                 778899********77777644 PP

  == domain 2  score: 24.2 bits;  conditional E-value: 2e-09
                 HHHTSTTHHHHHHHHHHHSCHHHH CS
         PUF   8 qLstdqyGnyvvQkllehateeqk 31 
                  L+++++Gn++vQ+++eh t+eq+
  EEA22954.1 438 PLMVNRFGNFLVQRCFEHGTPEQV 461
                 69*******************996 PP

  == domain 3  score: 25.7 bits;  conditional E-value: 6.7e-10
                 HHGGGHHHHHTSTTHHHHHHHHHHHSCHHH CS
         PUF   1 sikgnlvqLstdqyGnyvvQkllehateeq 30 
                 sikgn ++Ls d +G++v+Qk ++ +++e+
  EEA22954.1 467 SIKGNTLSLSMDAFGCHVIQKAFD-CVPEE 495
                 69**********************.66665 PP

  == domain 4  score: 5.5 bits;  conditional E-value: 0.0017
                 TSTTHHHHHHHHHH CS
         PUF  11 tdqyGnyvvQklle 24 
                 +++y+++v Qkl+e
  EEA22954.1 513 IHRYACHVWQKLFE 526
                 79**********98 PP

  == domain 5  score: 9.9 bits;  conditional E-value: 6.6e-05
                 HHHTSTTHHHHHHHHHHHSCHHHHH CS
         PUF   8 qLstdqyGnyvvQkllehateeqkk 32 
                 + +    G+ vvQ+++e ++e +k+
  EEA22954.1 550 EVALGETGSLVVQNIFENCVEDEKR 574
                 5566678*************99876 PP

  == domain 6  score: 11.5 bits;  conditional E-value: 2.1e-05
                 GGHHHHHTSTTHHHHHHHHHHHSCH CS
         PUF   4 gnlvqLstdqyGnyvvQkllehate 28 
                  n+  Ls  q+Gn+ +Q++ eh  +
  EEA22954.1 582 ANIDLLSHGQFGNWCIQHICEHGAL 606
                 678889999************9444 PP

  == domain 7  score: 14.5 bits;  conditional E-value: 2.4e-06
                 HTSTTHHHHHHHHHHHSCHHHHHHH CS
         PUF  10 stdqyGnyvvQkllehateeqkkli 34 
                 s dq+++ vv+k+l+  ++e  +++
  EEA22954.1 624 SMDQFASKVVEKCLKIGGPEFLDRY 648
                 66*************9888887765 PP

  == domain 8  score: 16.0 bits;  conditional E-value: 7.7e-07
                 HHHTSTTHHHHHHHHHHHSCHHHHH CS
         PUF   8 qLstdqyGnyvvQkllehateeqkk 32 
                 +++ dqyGny++Q++l  a + q++
  EEA22954.1 666 DIAGDQYGNYLIQWILVNAAPHQRE 690
                 6777************998777766 PP

  == domain 9  score: -2.0 bits;  conditional E-value: 0.4
                 GGGHHHHHTSTTHHHH CS
         PUF   3 kgnlvqLstdqyGnyv 18 
                 +++ v+L   ++G++v
  EEA22954.1 697 RKHMVSLRGSKFGSRV 712
                 56777777789***98 PP

>> zf-C2H2_assoc  Unstructured conserved, between two C2H2-type zinc-fingers
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.7   0.5     0.033   2.9e+02      21      60 ..      46      87 ..      34     102 .. 0.72
   2 ?    7.3   0.9    0.0006       5.4      53      73 ..     223     243 ..     212     250 .. 0.83

  Alignments for each domain:
  == domain 1  score: 1.7 bits;  conditional E-value: 0.033
  zf-C2H2_assoc 21 dpesqsisrsttPGssnvteesGaGGGlsqtG..svqedsPh 60
                   d+   s s st P ssn      +    sq+   s+q  s h
     EEA22954.1 46 DKTRESRSVSTPPQSSNQDRSIFVRATASQATvvSAQAPSMH 87
                   55556667789******8887777777777652245555555 PP

  == domain 2  score: 7.3 bits;  conditional E-value: 0.0006
  zf-C2H2_assoc  53 svqedsPhPssPssvdlGeev 73 
                     vq+ sPhP +Ps+   G  +
     EEA22954.1 223 GVQDPSPHPWTPSANSTGMTA 243
                    59***********99988765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (768 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       584  (0.0325729); expected 358.6 (0.02)
Passed bias filter:                      438  (0.0244297); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.66u 0.30s 00:00:00.96 Elapsed: 00:00:00.46
# Mc/sec: 4969.12
//
Query:       EEA22955.1  [L=540]
Description: ER to Golgi transport protein (Sly41), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.8e-60  204.1  16.1    3.4e-60  203.8  16.1    1.1  1  TPT             Triose-phosphate Transporter family
    3.4e-08   33.7  33.9    2.7e-05   24.4  12.6    2.9  2  EamA            EamA-like transporter family


Domain annotation for each model (and alignments):
>> TPT  Triose-phosphate Transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  203.8  16.1   3.8e-64   3.4e-60       2     289 ..     125     446 ..     124     447 .. 0.92

  Alignments for each domain:
  == domain 1  score: 203.8 bits;  conditional E-value: 3.8e-64
         TPT   2 klgllfllWYllnvvfnilnKkilnvfpyPltvsavqllvgsvlilvlwal.glkk............rpkisseflkailplalvktlghvlavvsls 87 
                 kl  l+++WY+++ v+n   K il ++p P+t++ +q++  s ++l+l     l              + + s e++++ lpla +++lgh+l+ ++ s
  EEA22955.1 125 KLIGLCIIWYMTSAVTNTSSKSILTALPKPVTLTIIQFAFVSFWCLILTYCsSLFPglktvipalrngILRPSREVIITALPLAGFQLLGHILSSMATS 223
                 57789*********************************9998887776444244446777999996665555666999********************* PP

         TPT  88 kvaVSfthtvKasePiFtvilsrlllgeklsllvylsLlpivgGvalasvtElsFnligfisAlisnltfslrnifsKkllkk.lkd...........l 174
                 +++VS  ht+K + P+Ftv+  r++++ ++  + ylsL+p+ +Gv+la +t  s n++g+i+Al++ l+f+++nifsKkl+++ ++            l
  EEA22955.1 224 QIPVSLVHTIKGLSPLFTVLAYRVFFRIRYARATYLSLVPLTMGVMLACATGFSANFFGIICALLAALVFVSQNIFSKKLFNEaSRAeadpspsarrkL 322
                 **********************************************************************************97444688999****** PP

         TPT 175 dalnlfaiitilslllllPvallvegvlktpsllkst.........kvslkevllllllsgvlfhlynqvaymvLervspvthsvantvKrvvvIvlsv 264
                 d+lnl+ + ++l++ll+lP++l+ eg+    ++l+++         +    +++l+ + +gv ++++n++a+ +L++vspv++sva+ +Krv+vIv+++
  EEA22955.1 323 DKLNLLYYCSALAFLLTLPIWLFSEGFSLISDILSNGaisltekkdSLDHGALFLEFVFNGVSHFAQNILAFVILSMVSPVSYSVASLIKRVFVIVVAI 421
                 **************************99888888888888888743355788999******************************************** PP

         TPT 265 lvfknpvsllnaiGtavaivGvflY 289
                 + f+ + ++ +a+G  ++ +G +lY
  EEA22955.1 422 IWFGSSTTSTQAVGIGLTFFGLYLY 446
                 ************************* PP

>> EamA  EamA-like transporter family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.9  13.3   5.2e-06     0.047       6     134 ..     129     270 ..     125     273 .. 0.86
   2 !   24.4  12.6     3e-09   2.7e-05       2     134 ..     281     445 ..     280     446 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 5.2e-06
        EamA   6 lallaalfwaiyfvlskillrkv.spltltfvrfliagilllii...............allkegkl..aklslkdwllllllgllgtvlafllffyal 86 
                 l+++  +++a++ + sk +l+ +  p+tlt ++f + ++ +li+               al     +   ++s++ ++  l l+ +  +l+++l  +a 
  EEA22955.1 129 LCIIWYMTSAVTNTSSKSILTALpKPVTLTIIQFAFVSFWCLILtycsslfpglktvipALR----NgiLRPSREVIITALPLAGFQ-LLGHILSSMAT 222
                 667777888999999998888886799**************999999988888886532332....233568888899999999877.67889****** PP

        EamA  87 kktsasnaslitslePvftlilsvlllgekltlkqllgivlillGvll 134
                 + +++s +  i  l+P+ft++   ++++ +    ++l++v   +Gv+l
  EEA22955.1 223 SQIPVSLVHTIKGLSPLFTVLAYRVFFRIRYARATYLSLVPLTMGVML 270
                 **********************************************98 PP

  == domain 2  score: 24.4 bits;  conditional E-value: 3e-09
        EamA   2 lgillallaalfwaiyfvlskillrkv...............spltltfvrfliagilllii..................allkegklaklslkdwlll 67 
                 +gi+ allaal++ +  ++sk+l+++                + l l+ + + +a++l l+i                  + l+e+k+ +l++ +++l 
  EEA22955.1 281 FGIICALLAALVFVSQNIFSKKLFNEAsraeadpspsarrklDKLNLLYYCSALAFLLTLPIwlfsegfslisdilsngaISLTEKKD-SLDHGALFLE 378
                 79*********************999999999999999999999999999999*********77777777777777777655666666.7777777777 PP

        EamA  68 lllgllgtvlafllffyalkktsasnaslitslePvftlilsvlllgekltlkqllgivlillGvll 134
                 +++  ++ ++ ++l f  l+ +s+   s+++++  vf+++ +++++g + t++q +gi+l ++G++l
  EEA22955.1 379 FVFNGVSHFAQNILAFVILSMVSPVSYSVASLIKRVFVIVVAIIWFGSSTTSTQAVGIGLTFFGLYL 445
                 ****************************************************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (540 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       950  (0.0529868); expected 358.6 (0.02)
Passed bias filter:                      483  (0.0269396); expected 358.6 (0.02)
Passed Vit filter:                        45  (0.0025099); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.66u 0.29s 00:00:00.95 Elapsed: 00:00:00.48
# Mc/sec: 3395.63
//
Query:       EEA22956.1  [L=820]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (820 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       793  (0.04423); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.71u 0.26s 00:00:00.97 Elapsed: 00:00:00.43
# Mc/sec: 5719.61
//
Query:       EEA22957.1  [L=771]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    8.5e-28   97.5  24.7    8.5e-28   97.5  24.7    2.4  2  Choline_transpo  Plasma-membrane choline transporter


Domain annotation for each model (and alignments):
>> Choline_transpo  Plasma-membrane choline transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   4.3     0.062   1.1e+03     258     315 ..     296     366 ..     294     376 .. 0.57
   2 !   97.5  24.7   4.7e-32   8.5e-28       1     324 [.     411     736 ..     411     737 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.062
  Choline_transpo 258 lgkllialltgliaylllkatltnpe.............elnsplvpllvvfiiayliasiflsvyesavd 315
                       g l+  +l+gl+a  +l    t+p              ++++ +++l +  ++++li+ + l++++s v 
       EEA22957.1 296 WGHLFLICLIGLFATAFLVWLHTAPPsdgrwklvdtiytTIHKSYFLLGIYTLVSILISLLWLALLRSYVR 366
                      55566666666664322222222222345666666666666777777777777777777777777766665 PP

  == domain 2  score: 97.5 bits;  conditional E-value: 4.7e-32
  Choline_transpo   1 iillivavllllllivlrkrirlaiallkvaskaiksnpslllvplltllllllvsafwivvavalylassgestdkvnsgsesglaavefess 94 
                      ii +i+a l+++ +++ r+    ai++l+ a++++ snp ll++ l +l++++ ++++w++ + +++l +s  s+          +   +f +s
       EEA22957.1 411 IIPFILATLWIYAIVRNRHSTGKAISILEFACRVLASNPALLALGLGILVVTVSWTWLWMIMFTRIFLGGSIRSD----------N---SFVIS 491
                      577899************************************************************977776554..........2...35667 PP

  Choline_transpo  95 skvkalllyllfgllWtleflralqqvtvagavasWYfskkkdlp...skfpvlkslkraltyhlGSialgSlilaivqllrlileylekklkk 185
                       + ++l +y+++++lW+l ++ ++q+ ++a++v++WYf+ + +lp   s++ v++++++alt+ +GSi l Sli+ +++l+ l+l        +
       EEA22957.1 492 ISSWWLGAYFILVYLWSLGVIAGIQRSVTAATVSQWYFH-RLALPaptSAQIVRAAMSHALTTLFGSISLFSLIVLLLRLPLLVLPK------R 578
                      8899***********************************.333444444445*********************************94......2 PP

  Choline_transpo 186 kenavakcllcclkcclwclekflkflnrnayimvaiyGksFcesakdafellkrngl.rvavld..................svvdfvlflgk 260
                        +++a ++ +       +   +   +n  ++++ ai++++  +sa+  +++ +     ++  l+                   +++++l+  +
       EEA22957.1 579 IASVIALFAYSL------IPSPIAALVNPLTLTYAAIHSQPLAQSARGFTQMAVFSSFsTTGGLYapssisrggsnanslisyRLSKMILHACR 666
                      233333333333......46778889*********************9999988888756666667777777777777777777********** PP

  Choline_transpo 261 llialltgliaylllkatltnpe......elnsplvpllvvfiiayliasiflsvyesavdtifvcfaeD 324
                      ++++l+ g+ +++  +++l  +          +++++ l+++ i++ ++  + +v+  +vd+ +vc+a +
       EEA22957.1 667 FAMSLALGFGGWVTAARNLDVSGgnstirGSLYAYIIGLIAGTIGWGVLGSMENVLACVVDSALVCWASE 736
                      ************9999777777799*9*96666669*******************************975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (771 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       795  (0.0443416); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.29s 00:00:00.94 Elapsed: 00:00:00.46
# Mc/sec: 5059.43
//
Query:       EEA22958.1  [L=276]
Description: secretion related GTPase SrgD [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    9.5e-49  165.1   0.0    2.5e-46  157.2   0.0    2.1  1  Ras          Ras family
    1.2e-29  102.9   0.0      5e-19   68.7   0.0    2.3  2  Roc          Ras of Complex, Roc, domain of DAPkinase
    1.2e-09   37.9   0.0    3.9e-09   36.2   0.0    1.7  2  Arf          ADP-ribosylation factor family
    5.8e-09   35.8   0.0    1.4e-08   34.5   0.0    1.6  1  GTP_EFTU     Elongation factor Tu GTP binding domain
      3e-07   30.0   0.0    6.6e-07   28.9   0.0    1.6  1  Gtr1_RagA    Gtr1/RagA G protein conserved region
    9.2e-05   22.5   0.1     0.0008   19.5   0.0    2.4  2  MMR_HSR1     50S ribosome-binding GTPase
     0.0055   16.6   0.0          1    9.2   0.0    2.2  2  RsgA_GTPase  RsgA GTPase
  ------ inclusion threshold ------
      0.059   13.7   0.4       0.44   10.8   0.2    2.5  2  AAA_22       AAA domain


Domain annotation for each model (and alignments):
>> Ras  Ras family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  157.2   0.0   1.1e-49   2.5e-46       1     161 [.      10     221 ..      10     222 .. 0.98

  Alignments for each domain:
  == domain 1  score: 157.2 bits;  conditional E-value: 1.1e-49
                 EEEEEESTTSSHHHHHHHHHHSSCSSSCTTTSSEEEEEEEEEET...................................TEEEEEEEEEETTSGGGHHH CS
         Ras   1 KlvlvGdsavGKtslllrfvkdkFkeeyesTigvdfytkeievd...................................gkevkleiwDTAGqeefksl 64 
                 Klv +Gds++GK+sl +r  +++F+ +++ Tigv+f ++ + v                                    +k++kl++wDTAGqe +ks+
  EEA22958.1  10 KLVCIGDSGTGKSSLSIRLCEGRFSPTHDVTIGVEFGSRVVPVGppasksldidhynttgsptqlqtpatgtpekngstQKKMKLSLWDTAGQETYKSV 108
                 89*********************************9999999988999999999************************99******************* PP

                 HHHHHTTESEEEEEEETTBHHHHHTHHHHHHHHHHHSTTTSEEEEEEETTTGGG...............G-SS-HHHHHHHHHHHT.SEEEEEBTTTTC CS
         Ras  65 relyyrdaegillvyditsresfenvkkwveeikrvaeenvpivLvGnKvDlee...............kravsteegeelakelg.lkfletSAktne 147
                 +++y+r+a+g+llv+dit+ ++f +v++w+++++++ae+ +++vLvGnK+Dl+                +r v+++e+ee++++++ ++++etSAk+ e
  EEA22958.1 109 TRSYFRGASGALLVFDITRPSTFASVTSWLQDLRQIAEDGIVVVLVGNKCDLAGnekssdsqgegqtknQRRVTRQEAEEWCRQNNvIRYIETSAKSGE 207
                 ****************************************************9999******************************9************ PP

                 THHHHHHHHHHHHH CS
         Ras 148 nveeafeellreil 161
                 +ve af e++++i+
  EEA22958.1 208 GVERAFLEVAERIY 221
                 **********9986 PP

>> Roc  Ras of Complex, Roc, domain of DAPkinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   32.7   0.0   3.2e-11   7.2e-08       1      41 [.      10      50 ..      10      76 .. 0.80
   2 !   68.7   0.0   2.2e-22     5e-19      47     120 .]      83     160 ..      57     160 .. 0.80

  Alignments for each domain:
  == domain 1  score: 32.7 bits;  conditional E-value: 3.2e-11
                EEEEESSTTSSHHHHHHCHCT-CCC-EEETTTTEEEEEEEC CS
         Roc  1 KvvlvGdsgvGKtsllkrfvedkfsekekstigvdfltkev 41
                K+v++Gdsg+GK+sl  r++e++fs++++ tigv+f ++ v
  EEA22958.1 10 KLVCIGDSGTGKSSLSIRLCEGRFSPTHDVTIGVEFGSRVV 50
                89**********************************98754 PP

  == domain 2  score: 68.7 bits;  conditional E-value: 2.2e-22
                 CTTBTTTTCEEEEEEEE-SGGCTTTT-HHHHCTSCEEEEEEE...GHHHHCHHHHHHHHHHHCSSS.-EEEEEE-TTT CS
         Roc  47 vendkkvkkvklniWDtaGqerfrslhplylreaalailvyd...srssenlkeWlkelkkvagks.pvilvgnkiDl 120
                  +n +++kk+kl++WDtaGqe ++s++++y+r+a+ a+lv+d    ++++++ +Wl++l++ a++  +v+lvgnk+Dl
  EEA22958.1  83 EKNGSTQKKMKLSLWDTAGQETYKSVTRSYFRGASGALLVFDitrPSTFASVTSWLQDLRQIAEDGiVVVLVGNKCDL 160
                 346677889*********************************744447899************98626779*****95 PP

>> Arf  ADP-ribosylation factor family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.0      0.65   1.4e+03      15      41 ..       9      35 ..       4      46 .. 0.78
   2 !   36.2   0.0   1.7e-12   3.9e-09      48     172 ..      82     217 ..      64     220 .. 0.79

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 0.65
                EEEEEEESTTSSHHHHHHHHHHSSCEE CS
         Arf 15 lrilllGLDnaGKtTilkklkleelvt 41
                ++++ +G  ++GK+ +  +l +++++ 
  EEA22958.1  9 AKLVCIGDSGTGKSSLSIRLCEGRFSP 35
                6899999999*****999999988764 PP

  == domain 2  score: 36.2 bits;  conditional E-value: 1.7e-12
                 EEEEEEEETTEEEEEEEE-SSGGGGGGGGGGCTTESEEEEEEETT-CTTHHHHHHHHHHHCTSGCCTTSEEEEEEE-TTSTTSS-HHHHHHHTTGGG.. CS
         Arf  48 fnveeleiknlkftvwDvGGqeklRplWknYfektdavifvvDsadreRleeakeeLkalleeeelkevallvlaNKqDlpealseeelrellglee.. 144
                 ++ +  + k++k+++wD  Gqe+ +++ ++Yf+   + + v D +  + +++  + L+ l +  e   +++++++NK Dl++  ++++ + + + ++  
  EEA22958.1  82 PEKNGSTQKKMKLSLWDTAGQETYKSVTRSYFRGASGALLVFDITRPSTFASVTSWLQDLRQIAE-DGIVVVLVGNKCDLAGNEKSSDSQGEGQTKNqr 179
                 344455779**************************************************998887.56777778******9998888777665555545 PP

                 ..........SSSSSSEEEEEEBTTTTBTHHHHHHHHH CS
         Arf 145 ..........lkgkrkleiqkcsavkgeglkeglewls 172
                            ++++ +  +++sa +geg++ ++  ++
  EEA22958.1 180 rvtrqeaeewCRQNNVIRYIETSAKSGEGVERAFLEVA 217
                 65555544444477788888999999999998876665 PP

>> GTP_EFTU  Elongation factor Tu GTP binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.5   0.0   6.2e-12   1.4e-08       7     187 ..      12     216 ..       6     225 .. 0.63

  Alignments for each domain:
  == domain 1  score: 34.5 bits;  conditional E-value: 6.2e-12
                 EEEESTTSSHHHHHHHHHHHTTSSCHHHHHH...HHHST..............HCHSHHHHHHTSCSSCEEEEEE.....TTCSSEEEEEEEESSSGGG CS
    GTP_EFTU   7 giighvDhGKtTLtdrLlyktgaiskkgeka...eeerv..............lDtlkeErergiTiksaaisle.....ketkkylinliDtPGHvdF 83 
                 + ig+  +GK++L+ rL    g+ s  + ++   e   +              lD          T   + ++       +++kk +++l Dt G + +
  EEA22958.1  12 VCIGDSGTGKSSLSIRLC--EGRFSPTHDVTigvE---FgsrvvpvgppasksLDIDHYNTTGSPTQLQTPATGTpekngSTQKKMKLSLWDTAGQETY 105
                 566677777777766666..445555445553221...22333555555555544444444444444444443336765558999************** PP

                 HHHHHHHHHT-SEEEEEEETTTBSTHHHHHHH....HHHHHTTTEEEEEEESCGSTHHHHHHHHHHH.HHHHHHH..HHHHHHHHHTTTTTEEEEEEBT CS
    GTP_EFTU  84 skevirglrvlDgavlvvdaveGvepqteevl....rlalkegvpiivfiNKmDrlkaelkeiveev.kqklsrk..eeklekygekgekevpvvfgSa 175
                  + +    r + ga+lv+d+++  +  + + +    r++ + g+ ++++ NK+D +++e +   +   ++k +r+   ++ e+ + ++++ +  + +Sa
  EEA22958.1 106 KSVTRSYFRGASGALLVFDITRPSTFASVTSWlqdlRQIAEDGIVVVLVGNKCDLAGNEKSSDSQGEgQTKNQRRvtRQEAEE-WCRQNNVIRYIETSA 203
                 9988888**************98766666655222277888888899999******554444444330333333333344444.4444479******** PP

                 TTTBTHHH.HHHH CS
    GTP_EFTU 176 lkgegvkt.llea 187
                 ++gegv+  +le+
  EEA22958.1 204 KSGEGVERaFLEV 216
                 ******9634444 PP

>> Gtr1_RagA  Gtr1/RagA G protein conserved region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.9   0.0     3e-10   6.6e-07       2     159 ..      11     203 ..      10     232 .. 0.76

  Alignments for each domain:
  == domain 1  score: 28.9 bits;  conditional E-value: 3e-10
   Gtr1_RagA   2 vLLmGksgsGKtsmrsiiFd.nylardtlrlgati...................................dveksevrflgnltlnlwDcgGqeafvee 64 
                 ++ +G sg GK+s+   + +  +++++ +++g+                                        +++  + ++++l+lwD  Gqe++   
  EEA22958.1  11 LVCIGDSGTGKSSLSIRLCEgRFSPTHDVTIGVEFgsrvvpvgppasksldidhynttgsptqlqtpatgTP-EKNGSTQKKMKLSLWDTAGQETYKSV 108
                 556677777777776666652356666666666666677777777777777777777777777777776433.34445789************998777 PP

   Gtr1_RagA  65 ylssqkeeifrnvgvliyVfDvesreleedletlkeilealrqyspeakvfvli.hKmDliqedereeifeerkeeireeiekleke.......eiqff 155
                 +      + fr  +  + VfD++    ++++++ ++ l+ lrq+ ++  v vl+ +K+Dl  +++ ++ + e +++ +++++++e e        i++ 
  EEA22958.1 109 T-----RSYFRGASGALLVFDIT---RPSTFASVTSWLQDLRQIAEDGIVVVLVgNKCDLAGNEKSSDSQGEGQTKNQRRVTRQEAEewcrqnnVIRYI 199
                 5.....677888888889*****...999************************978********99999999999998888866665566666678888 PP

   Gtr1_RagA 156 aTSi 159
                  TS 
  EEA22958.1 200 ETSA 203
                 8876 PP

>> MMR_HSR1  50S ribosome-binding GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.5   0.0   3.6e-07    0.0008       2     101 ..      11     145 ..      10     157 .. 0.58
   2 ?   -0.6   0.0      0.63   1.4e+03      34      34 ..     183     183 ..     157     229 .. 0.49

  Alignments for each domain:
  == domain 1  score: 19.5 bits;  conditional E-value: 3.6e-07
                 EEEEESTTSSHHHHHHHHHT.................STEEESSSTTSSSSEEEEEEEETTEE........................EEEEECGGCSSH CS
    MMR_HSR1   2 vaivGrpNvGKStLinaltg.................ekaivsdkpgtTrdinegrvklkgke........................ielvDtpGlieg 59 
                  +++G + +GKS+L  +l++                 +++ v+  + + +di +++ +                             + l+Dt+G  e 
  EEA22958.1  11 LVCIGDSGTGKSSLSIRLCEgrfspthdvtigvefgsRVVPVGPPASKSLDIDHYNTT----GsptqlqtpatgtpekngstqkkmkLSLWDTAG-QE- 103
                 5789***************733333333333343332244555555555555555444....0334455556666666666666666********.55. PP

                 HHHHHHHHHHHHHHHCTSEEEEEEETT.....TTCSHHHHHHHHHHH CS
    MMR_HSR1  60 aseekglgkaflaleeadlillvvdas.....eeklkpldeeleell 101
                   + k++++++ +   a+ +llv+d++       +++   ++l ++ 
  EEA22958.1 104 --TYKSVTRSYFR--GASGALLVFDITrpstfA-SVTSWLQDLRQIA 145
                 ..66689999995..588999999998653331.2222233333332 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.63
                 S CS
    MMR_HSR1  34 r 34 
                 r
  EEA22958.1 183 R 183
                 2 PP

>> RsgA_GTPase  RsgA GTPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.2   0.0   0.00047         1     103     128 ..      12      37 ..       6      48 .. 0.78
   2 !    5.4   0.0     0.007        16      39      76 ..     141     178 ..     105     218 .. 0.71

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.00047
                  EEECSTTSSHHHHHHHHCTT-----S CS
  RsgA_GTPase 103 vlvGqSGvGKStLinallpelelktg 128
                  v +G SG GKS+L  +l +     t+
   EEA22958.1  12 VCIGDSGTGKSSLSIRLCEGRFSPTH 37 
                  789**********9888776555555 PP

  == domain 2  score: 5.4 bits;  conditional E-value: 0.007
                  HHHHHHTT-EEEEEEE-GGG--HHHHHHHHHHHHHHTT CS
  RsgA_GTPase  39 LvlaeekgiepvivlnKiDlleeeeeleelkeelealg 76 
                  L ++ e gi +v+v nK+Dl+ +e++ +++ e  ++ +
   EEA22958.1 141 LRQIAEDGIVVVLVGNKCDLAGNEKSSDSQGEGQTKNQ 178
                  6788899**************99994444444333333 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.2    0.0002      0.44       8      50 ..      11      57 ..       9     162 .. 0.69
   2 ?   -1.5   0.0       1.3   2.8e+03      22      52 ..     178     205 ..     170     236 .. 0.56

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.0002
      AAA_22  8 lvvtGesGtGKTtllrrlleqldeeakaee.......erpevvfvtlpss 50
                lv++G sGtGK+ l  rl e      ++++        +++vv v +p+s
  EEA22958.1 11 LVCIGDSGTGKSSLSIRLCEGR---FSPTHdvtigveFGSRVVPVGPPAS 57
                79**********9877776654...2222244555555555555555555 PP

  == domain 2  score: -1.5 bits;  conditional E-value: 1.3
      AAA_22  22 lrrlleqldeeakaee..erpevvfvtlpssts 52 
                  rr+++q      aee  ++  v+++  +s +s
  EEA22958.1 178 QRRVTRQE-----AEEwcRQNNVIRYIETSAKS 205
                 44444443.....44457777777544444443 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (276 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       533  (0.0297284); expected 358.6 (0.02)
Passed bias filter:                      428  (0.0238719); expected 358.6 (0.02)
Passed Vit filter:                        49  (0.002733); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.59u 0.29s 00:00:00.87 Elapsed: 00:00:00.49
# Mc/sec: 1708.69
//
Query:       EEA22959.1  [L=739]
Description: protein O-mannosyl transferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-87  292.9  15.8      2e-87  292.9  15.8    1.8  2  PMT       Dolichyl-phosphate-mannose-protein mannosyltransfer
      2e-64  216.9  13.7      2e-64  216.9  13.7    2.6  2  PMT_4TMC  C-terminal four TMM region of protein-O-mannosyltra
    2.1e-35  122.3   0.5    3.2e-35  121.6   0.5    1.2  1  MIR       MIR domain


Domain annotation for each model (and alignments):
>> PMT  Dolichyl-phosphate-mannose-protein mannosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  292.9  15.8   3.3e-91     2e-87       2     244 ..      63     305 ..      62     306 .. 0.99
   2 ?   -2.8   1.0      0.65   3.9e+03     139     169 ..     670     699 ..     636     715 .. 0.61

  Alignments for each domain:
  == domain 1  score: 292.9 bits;  conditional E-value: 3.3e-91
         PMT   2 iltllallirlwrlslpnsvvfdevhfgkfasdYlehsffmdvhpplgkmllalggyLagkdgnftfesigaeyypenvpyvslRlfsallgslivplv 100
                 i+t+l++++r++r++l n v++de+hfgkf+s Yl+++f++dvhpplgk l++l+gyLag++g+f+f+s   e+ype v+y ++R+f+a++g+++vpl+
  EEA22959.1  63 IFTALSFFTRMYRIGLSNIVTWDEAHFGKFGSHYLKREFYFDVHPPLGKILVGLSGYLAGYNGSFEFKSG--EQYPEDVNYTFMRVFNAFFGVVCVPLA 159
                 799*******************************************************************..9************************** PP

         PMT 101 yltllelgfskltallaallvllenslitlsryilldspLlfftllsmyclvkfe..rkapfsrswwlwllltgvalglavsvKwvglftvllvgllli 197
                 y+t++el+f++ t++l +l+vl+ens+ t+sr+illds+Ll ft ++++c+ +f+  r++ fs +w++wl+ltgv++g+++s+K vglf ++lvgl ++
  EEA22959.1 160 YYTARELNFRRPTVWLVTLMVLFENSYATISRFILLDSMLLCFTFTTVLCWARFHrlRNQSFSVEWFAWLFLTGVSIGCVCSIKLVGLFCTALVGLHTA 258
                 *********************************************************9999************************************** PP

         PMT 198 welwqllgdkslllksivkhllaralaliviPvtlylavftvhfwll 244
                  +lw+++gd +++  +   h++ar+++li++P+++y++ f++hf +l
  EEA22959.1 259 EDLWNKFGDVKMPVTTLARHVVARVICLIIVPLLVYMFSFYLHFLIL 305
                 ********************************************876 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 0.65
         PMT 139 pLlfftllsmyclvkferkapfsrswwlwll 169
                 +L f +l++ +c+ ++ r + +++ +w+ ++
  EEA22959.1 670 ALYFAILTAGFCVDWVTR-KLGTKVQWAIYI 699
                 444555555555555543.335555555544 PP

>> PMT_4TMC  C-terminal four TMM region of protein-O-mannosyltransferase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   2.2     0.064   3.8e+02     154     179 ..     269     302 ..     187     318 .. 0.80
   2 !  216.9  13.7   3.3e-68     2e-64       1     199 []     538     735 ..     538     735 .. 0.96

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.064
    PMT_4TMC 154 k........klvklivvvvllvlviavFiffspl 179
                 k        ++v+++++++++ l++++F f++ +
  EEA22959.1 269 KmpvttlarHVVARVICLIIVPLLVYMFSFYLHF 302
                 0445556668899999999999999999999875 PP

  == domain 2  score: 216.9 bits;  conditional E-value: 3.3e-68
    PMT_4TMC   1 Flkkflelqkamltsnnaltes....hpyaSepyeWplllrgisywtkneekkqiyllGNpvlwwlstiallvfvllllalllrrqrgvkdl.eeeetr 94 
                 F+k+f++l++am+tsnnal+++    +++aS+ ++Wpll+ g+++++++++  +++llGNp+++w st++ll f l+++++l+r+qrg+ dl ++e ++
  EEA22959.1 538 FFKDFIHLNVAMMTSNNALVPDpdkqDDLASKFWQWPLLHVGLRMCSWDDNIVKYFLLGNPLVYWGSTASLLGFGLIVAWYLIRWQRGYVDLsPSEIDQ 636
                 9********************559********************************************************************6667777 PP

    PMT_4TMC  95 llnsglflllgwalhylPfflmgRvlflhhYlpAllfailllaalldfllkslkkslkkkklvklivvvvllvlviavFiffspltyGlpgtseevkkl 193
                 ++++g+++l+gw+lhylPf +m+Rv+++hhY+pAl+fail++++++d+++++l +      +v++++++ l+++vi  F++f+ +++G++g+++++++l
  EEA22959.1 637 IHYAGIYPLIGWVLHYLPFAVMARVTYVHHYYPALYFAILTAGFCVDWVTRKLGT------KVQWAIYIPLYIAVISLFVVFKDIVFGMEGSNRQWEYL 729
                 *************************************************855444......569*********************************** PP

    PMT_4TMC 194 kwlssW 199
                 kwls+W
  EEA22959.1 730 KWLSTW 735
                 ****** PP

>> MIR  MIR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.6   0.5   5.4e-39   3.2e-35      11     184 ..     353     514 ..     352     526 .. 0.95

  Alignments for each domain:
  == domain 1  score: 121.6 bits;  conditional E-value: 5.4e-39
         MIR  11 LfHshqdeyltiseqqqkqevflritlypsadaanssraLWeievvqkd.....awrgglikwgkvyRlkHlaTgryLaseeekksplseseddqkevs 104
                 L Hsh ++y+++s+qqq       +t+y+++da+n+    W   + + +     +   +++ +g+v+Rl H +Tgr+L+s+    +p+++s   + evs
  EEA22959.1 353 LLHSHVQTYPEGSTQQQ-------VTCYHHKDANND----WFMYPNRYQpeydpEAPLRFLGDGDVIRLIHAQTGRNLHSHSV-AAPITKS---DWEVS 436
                 78***************.......************....*******998888778***************************.9***955...779** PP

         MIR 105 ayglegfegdnDkveifekksttgmksaklvprdsyvrlqHvvtgcwLhstsvklkkekfekvqqkvicakekedkeala 184
                 +yg+ ++ +++D+ +i    +   ++++k+++ ++ +rl+H   gc+L++ +v+l++++f+  q + +c ke+++++ ++
  EEA22959.1 437 CYGNTTIGDEKDHWKIEVVSDAASRDRSKIRTLTTAFRLRHEALGCYLRAGTVNLPQWGFK--QIETTCVKENKPRDVYT 514
                 *******999***8888889*****************************************..*************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (739 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       599  (0.0334096); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.61u 0.27s 00:00:00.88 Elapsed: 00:00:00.43
# Mc/sec: 5109.75
//
Query:       EEA22960.1  [L=567]
Description: MFS monosaccharide transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
     2e-104  350.0  10.2   2.4e-104  349.8  10.2    1.0  1  Sugar_tr    Sugar (and other) transporter
    6.9e-30  104.2  29.3    2.4e-23   82.6   9.2    2.1  2  MFS_1       Major Facilitator Superfamily
    2.7e-09   36.1  16.7    1.5e-07   30.4   5.4    2.8  3  MFS_2       MFS/sugar transport protein
  ------ inclusion threshold ------
      0.012   14.5   5.8       0.82    8.5   0.2    2.3  2  MFS_1_like  MFS_1 like family
      0.035   13.7   1.7      0.081   12.6   1.7    1.5  1  INSIG       Insulin-induced protein (INSIG)


Domain annotation for each model (and alignments):
>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  349.8  10.2  6.6e-108  2.4e-104       3     452 .]      25     464 ..      23     464 .. 0.92

  Alignments for each domain:
  == domain 1  score: 349.8 bits;  conditional E-value: 6.6e-108
                 HHHHHHHHHHHHHHHCGGGTHHHHHHHHTSTT--SHHHHHH...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS CS
    Sugar_tr   3 lvaalggllfgYdtgvigafltllkfaknfglsksksskeessvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgkns 101
                 ++++lg +lfgYd gv+++++t   f   f++ ++     e    +g +v+i+ +Ga+i+sl++g++gd++GR+ ++l ++++f++g++lq +a+   s
  EEA22960.1  25 VFVSLGVFLFGYDQGVMSGIITGWYFRDYFNQPSKA----E----IGTVVAILEIGALISSLLVGKIGDIIGRRRTILYGSLIFLVGGALQTFAT---S 112
                 6788999***************99954444444333....2....799***********************************************...9 PP

                 -TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS-TTHHHHHHHCCHHHHHHHHHHGGGS---HHHHHH CS
    Sugar_tr 102 vevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaifglglnktsnadgwrillglqlvpallllilllflPESPrylve 200
                 + ++++gR+++G+gvG+ s++vP+++sEi+p++ Rg+l  +  ++ ++G   + +++++ ++++++  wri+l lq+v+  ll+++ l++PESPr+l+ 
  EEA22960.1 113 LSIMMLGRIIAGLGVGALSTIVPVFQSEISPPHNRGKLACIEFTGNILGYAASVWVDYFCSYIESNYSWRIPLLLQCVMGSLLAAGSLLIPESPRWLLD 211
                 *****************************************************************9********************************* PP

                 TT-HHHHHHHHHHHHHC.....HHHHHHHHHHHHHHHHHHH.........HTTHHHHSH...HHHHHHHHHHHHHHTTHHHHHHHTTTHHHHSS-THH. CS
    Sugar_tr 201 kgkeeeakevlaklrge.....edadrelaeekdsleaeqeee....kaswkellssktvrqrlligvvlqifqqltGinaimyysptifenlglsks. 289
                 ++++ee   v+a+l g      e+    + +e+++++ ++ ++    + s+  ++++  + +r+li++  q++ ql+Gin+i yy+p +fe++g     
  EEA22960.1 212 NDHDEEGLIVIANLYGGgdihnEL----ARQEYREIKFNVLTQrqegERSYADMFRR--YYKRVLIAMSAQAMAQLNGINVISYYAPLVFESAGWPGRs 304
                 *************87774333333....44666666666655555569999999999..99**********************************9999 PP

                 .HHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHHHHHHHHHHHHHH..HHHHTTSS...CHHHHHHHHHHHHHHHTTTTHHHHHHHHHHSHTTTHHHH CS
    Sugar_tr 290 .llvtiivgvvnfvatfvaiflvdrfGRRtllllGaagmaicfvilgivalllvakskaasivaivfialfialfalgwgpvpwvlvsElfpqsvRska 387
                  +l+t+i   +  ++t+  ++lvd +GRR++ll Ga+ m++ + +++   +ll +   a  ++ +++++++ a+f+++wgp+pw++ +E+ p+s+R+k+
  EEA22960.1 305 aILMTGINALTYLASTIPPWYLVDDWGRRPILLSGAVAMMVSLSLMS--YFLLIDV-PATPNLTVICVMVYNAAFGASWGPIPWLYPPEILPLSIRAKG 400
                 9*********************************************9..5555555.3779************************************** PP

                 HHHHHHHHHHHHHHHHHHHHHHHCHHHT-HHHHHHHHHHHHHHHHHHHHS--STT--CCCCGGGT CS
    Sugar_tr 388 laiavavnwlanflisllfpiiteaigggyvflvfaglavlfiifvfffvpetkgrtleeieelf 452
                 +++++a+nw +nfl++ ++p++++ i+ +  +l+ a++++ +++ v+f +pet g+ le+++ lf
  EEA22960.1 401 ASLSTAANWAFNFLVGEVTPVLQDLIK-WRLYLIHAFFCACSFVLVYFLYPETSGVRLEDMNVLF 464
                 ***************************.*********************************9987 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   82.6   9.2   6.7e-27   2.4e-23       2     240 ..      28     300 ..      27     301 .. 0.86
   2 !   28.3  16.0   2.3e-10   8.2e-07      10     176 ..     282     453 ..     269     461 .. 0.82

  Alignments for each domain:
  == domain 1  score: 82.6 bits;  conditional E-value: 6.7e-27
       MFS_1   2 llaaflsalarsilgpalpl.alaedlg.ispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlg 98 
                 +l++fl +++ ++ + +++  +  + ++  s++eig+++++  +ga+++sl++G ++d +Grrr++l g l+f++g++l +fa+sl +++++r+++Glg
  EEA22960.1  28 SLGVFLFGYDQGVMSGIITGwYFRDYFNqPSKAEIGTVVAILEIGALISSLLVGKIGDIIGRRRTILYGSLIFLVGGALQTFATSLSIMMLGRIIAGLG 126
                 7899**************999999999999999*******************************************66666866666************ PP

       MFS_1  99 agalfpagaaliadwfpkeergraigllsagfslGailgpllgglla...sslgWravfyilaivsllafvlfllllpeepperkrkspkeee...... 188
                  gal +++ ++ ++++p+ +rg+   +  +g+ lG++    +  +++   s+++Wr + ++ ++++ l++  + ll+pe+p+    + + ee+      
  EEA22960.1 127 VGALSTIVPVFQSEISPPHNRGKLACIEFTGNILGYAASVWVDYFCSyieSNYSWRIPLLLQCVMGSLLAA-GSLLIPESPRWLLDNDHDEEGlivian 224
                 ****************************************99996652225566**************977.445555555555555555555****** PP

       MFS_1 189 ..........................kgtgpaplvpawkallkdpvlwillialllfffgfsg...lltllplylqevlgl 240
                                            + g+++ ++ ++   k+     l+++++ +++ ++g   ++++ pl   e  g+
  EEA22960.1 225 lygggdihnelarqeyreikfnvltqRQEGERSYADMFRRYYKRV----LIAMSAQAMAQLNGinvISYYAPLV-FESAGW 300
                 ****99999999999988888888887777777777999999999....8888888877777777799999996.777777 PP

  == domain 2  score: 28.3 bits;  conditional E-value: 2.3e-10
       MFS_1  10 larsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll.f....a...sslwlllvlrvlqGlgag 100
                  ++++++  +p ++ e+ g+ + ++ l++++ al+++++++p  +l+d +Grr++ll g++++ ++l l++ f    +   ++l +++ + v  +++++
  EEA22960.1 282 NGINVISYYAP-LVFESAGWPGRSAILMTGINALTYLASTIPPWYLVDDWGRRPILLSGAVAMMVSLSLMSyFllidVpatPNL-TVICVMVYNAAFGA 378
                 34455666667.889999************************99**********************444445656552543333.45555666666667 PP

       MFS_1 101 alfpagaaliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeep 176
                 +  p+   +  ++ p + r+++ +l +a++ +   l   + ++l +++ Wr +++i+a++++ +fvl+++l+pe+ 
  EEA22960.1 379 SWGPIPWLYPPEILPLSIRAKGASLSTAANWAFNFLVGEVTPVLQDLIKWR-LYLIHAFFCACSFVLVYFLYPETS 453
                 777888899*******************999999*****************.89*************999999875 PP

>> MFS_2  MFS/sugar transport protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.4   5.4   4.1e-11   1.5e-07     229     340 ..      28     139 ..      20     142 .. 0.88
   2 !   13.0   0.5   7.8e-06     0.028     224     332 ..     264     380 ..     233     392 .. 0.77
   3 ?   -1.5   0.1       0.2     7e+02     393     424 ..     418     450 ..     402     457 .. 0.67

  Alignments for each domain:
  == domain 1  score: 30.4 bits;  conditional E-value: 4.1e-11
       MFS_2 229 llllfllaalalgvlnglllYyltyvlgngsaasvfllvv..tisallgiplwqplakrlgkkntyllgalltivllvlvlllqpsnlllflvllviag 325
                  l +fl+ +  +++   ++  y++++ ++ s+a++ ++v+   i+al++++l+ ++   +g+++t+l g+l+ +v+++l  ++  ++l ++++  +iag
  EEA22960.1  28 SLGVFLFGYDQGVMSGIITGWYFRDYFNQPSKAEIGTVVAilEIGALISSLLVGKIGDIIGRRRTILYGSLIFLVGGALQTFA--TSLSIMMLGRIIAG 124
                 57889999999999999999999999997777777666663269************************************999..9************* PP

       MFS_2 326 fgvgvaallpwsmla 340
                 +gvg++ ++++ + +
  EEA22960.1 125 LGVGALSTIVPVFQS 139
                 *****9999887765 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 7.8e-06
       MFS_2 224 raflillllfllaalalgvlnglllYyltyvlgngsaasvfllvvtisal....lgiplwqplakrlgkkntyllgalltivllvlvlll....qpsnl 314
                 r++ ++l++ +++a+a++ + +   Yy+  v +++ +   +++++t  ++    ++++  ++l+  +g++ + l+ga++++v l l+  +     p+  
  EEA22960.1 264 RYYKRVLIAMSAQAMAQLNGINVISYYAPLVFESAGWPGRSAILMTGINAltylASTIPPWYLVDDWGRRPILLSGAVAMMVSLSLMSYFllidVPATP 362
                 578889999************************77765544444432222245366666788***************9999877766555599988888 PP

       MFS_2 315 llflvllviagfgvgvaa 332
                  l+++++++++ ++g+++
  EEA22960.1 363 NLTVICVMVYNAAFGASW 380
                 888889999888888765 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 0.2
       MFS_2 393 qspqvvlalrllyavlpavlllvallllvr.yp 424
                 ++p  ++ +++ + ++ a +++ +++l+++ yp
  EEA22960.1 418 VTPVLQDLIKWRLYLIHAFFCACSFVLVYFlYP 450
                 555555556666666666666666666655554 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.2   0.00023      0.82      32      74 ..      58     100 ..      46     173 .. 0.87
   2 ?    7.8   1.2   0.00036       1.3     241     368 ..     284     418 ..     247     428 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.00023
  MFS_1_like  32 kaseigiitlilpltsilsppiwgvlaDrfgkrkkvvilslll 74 
                 + +eig +++il + +++s++++g + D +g+r +++  sl++
  EEA22960.1  58 SKAEIGTVVAILEIGALISSLLVGKIGDIIGRRRTILYGSLIF 100
                 5689*******************************88776665 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.00036
  MFS_1_like 241 wgiienFlflYLkelgasntllGslvalgvvaeiplfffaeklleklGhvklliiallayilrfllyaii......enawlvlpievLhgisfgllwaa 333
                  ++i  ++ l +++ g ++  +  ++ + ++  +   +   +l++  G + +l+ + +a+++ ++l++++        + l+++  + + ++fg+ w+ 
  EEA22960.1 284 INVISYYAPLVFESAGWPGRSAILMTGINALTYLASTIPPWYLVDDWGRRPILLSGAVAMMVSLSLMSYFllidvpATPNLTVICVMVYNAAFGASWGP 382
                 56666666666666666666666666666666666666667899****************************99998999******************9 PP

  MFS_1_like 334 av.eyvskiapksleatgqgllsglyfglGralGsl 368
                 +   y  +i p s++a+g +l +++ + +   +G++
  EEA22960.1 383 IPwLYPPEILPLSIRAKGASLSTAANWAFNFLVGEV 418
                 86268899**********999999998887777765 PP

>> INSIG  Insulin-induced protein (INSIG)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   1.7   2.3e-05     0.081     117     202 ..     314     441 ..     307     444 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 2.3e-05
       INSIG 117 ltlalvnpfLWyliDr.skpGfllsaavgllgtavllgl..npdlvpaPsaaa...................................saaaaaaaaee 177
                 lt ++  +  Wyl+D   +  +lls av+++ ++ l+++    d+  +P  +                                    s ++aa+ a +
  EEA22960.1 314 LTYLASTIPPWYLVDDwGRRPILLSGAVAMMVSLSLMSYflLIDVPATPNLTVicvmvynaafgaswgpipwlyppeilplsirakgaSLSTAANWAFN 412
                 5566666677****86489****************9994224444444555558999999999999999999999999999998887533333333334 PP

       INSIG 178 algg.as...qeslevaiwllsvLFcscv 202
                  l+g ++   q+ ++ +++l+  +Fc+c 
  EEA22960.1 413 FLVGeVTpvlQDLIKWRLYLIHAFFCACS 441
                 4445455777999***************5 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (567 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       404  (0.0225333); expected 358.6 (0.02)
Passed bias filter:                      243  (0.0135535); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.59u 0.27s 00:00:00.86 Elapsed: 00:00:00.43
# Mc/sec: 3955.30
//
Query:       EEA22961.1  [L=398]
Description: mitochondrial carrier protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    1.4e-18   66.6   0.9      2e-11   43.6   0.1    3.0  2  Mito_carr  Mitochondrial carrier protein


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.6   0.1   1.1e-15     2e-11       7      91 ..     149     231 ..     144     236 .. 0.93
   2 !   20.1   0.1   2.4e-08   0.00043      11      94 ..     278     379 ..     271     382 .. 0.72

  Alignments for each domain:
  == domain 1  score: 43.6 bits;  conditional E-value: 1.1e-15
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   7 kellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkr 91 
                 ++++aG  aga+++l+++Pld + +rl t++  + + +  ++++   k ++e G+rg + G++ +++r +   a+ f+++e++k 
  EEA22961.1 149 STFAAGFSAGAIQSLIAAPLDALQVRLRTSGVLEGQYQ--NMWEYGWKKLREIGVRGIFAGWSLSFMRDSLGYAVFFSSFEYVKS 231
                 6899****************************988744..5*****************************************996 PP

  == domain 2  score: 20.1 bits;  conditional E-value: 2.4e-08
                 HHHHHHHHHHHHHHHHHHHHHHHHH..............CCCSSTTTSCSS.............HHHHHHHHHHHHHH.HGGGTTHHHHHHHHHHHHHH CS
   Mito_carr  11 aGglagavatlvttPldvvKtrlqt..............qkksskksksaa.............ildvlkkiykeeGl.rglyrGllpnllrvapasal 81 
                 aG +a + ++++ +Pl ++                               +             + ++ k+  ++ G  r lyrG+l n +r++p++++
  EEA22961.1 278 AGIAASISQQIISYPLAIIQNLHYGrleyldhqatlrhsR----------PqmlkhyyhayqetFKRCQKRANRSGGWmRWLYRGFLRNSIRQVPSTSA 366
                 7888888888888998888753333555555544444331..........2334443334455677788888899998667****************** PP

                 HHHHHHHHHHHHC CS
   Mito_carr  82 kfvlyetlkrlll 94 
                  +v++e ++r + 
  EEA22961.1 367 GLVIFELMRRKYA 379
                 ********99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (398 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       452  (0.0252106); expected 358.6 (0.02)
Passed bias filter:                      372  (0.0207485); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 2620.14
//
Query:       EEA22962.1  [L=1019]
Description: transcription elongation complex subunit (Cdc68) [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.7e-57  193.9   0.0    1.7e-57  193.9   0.0    2.2  2  SPT16            FACT complex subunit (SPT16/CDC68)
      2e-55  187.0   0.0      2e-55  187.0   0.0    2.3  2  FACT-Spt16_Nlob  FACT complex subunit SPT16 N-terminal lobe d
    1.7e-25   89.9   0.0    2.7e-25   89.3   0.0    1.3  1  Peptidase_M24    Metallopeptidase family M24
    4.3e-15   55.9   0.4    2.3e-14   53.6   0.0    2.2  2  Rtt106           Histone chaperone Rttp106-like


Domain annotation for each model (and alignments):
>> SPT16  FACT complex subunit (SPT16/CDC68)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  193.9   0.0   3.8e-61   1.7e-57       1     151 []     542     692 ..     542     692 .. 0.99
   2 ?   -4.4   1.2         4   1.8e+04      88     106 ..     995    1013 ..     989    1018 .. 0.74

  Alignments for each domain:
  == domain 1  score: 193.9 bits;  conditional E-value: 3.8e-61
       SPT16   1 iyvdkkketillPifGiavPFhistiknvskseegdytylrinFnvpgsavgkkeealfknpeaifikeltfrskdekklqevfreikelkkkvkkrea 99 
                 ++vd+k++t+++Pi+G++vPFhi+tikn+sks+eg+y ylrinF +pg+ vg+k++++f+ p+a f+++lt+rskd++++  ++++i+el+k++ +re+
  EEA22962.1 542 VHVDHKASTVIVPIMGRPVPFHINTIKNASKSDEGEYAYLRINFLSPGQGVGRKDDQPFEDPSANFVRNLTLRSKDNDRFARIAQDITELRKNALRREQ 640
                 68*********************************************************99************************************** PP

       SPT16 100 ekkekedlveqekLilskskrkprLkdlyirpniegkklaGtleaheNGlRy 151
                 e+ke+ed+veq+kL++ +++r+++L+d+y+rp ++gk++ G++e+h+NGlRy
  EEA22962.1 641 ERKEMEDVVEQDKLVEIRNRRPVKLPDVYLRPPLDGKRVPGEVEIHQNGLRY 692
                 ***************************************************9 PP

  == domain 2  score: -4.4 bits;  conditional E-value: 4
       SPT16   88 kelkkkvkkreaekkeked 106 
                   el+k++kk+++e+ ++e 
  EEA22962.1  995 DELEKQAKKKDKESVDDER 1013
                  5889999999888766554 PP

>> FACT-Spt16_Nlob  FACT complex subunit SPT16 N-terminal lobe domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  187.0   0.0   4.4e-59     2e-55       1     160 [.       7     166 ..       7     167 .. 0.97
   2 ?   -4.3   0.9       3.2   1.4e+04     133     157 ..     987    1010 ..     984    1010 .. 0.75

  Alignments for each domain:
  == domain 1  score: 187.0 bits;  conditional E-value: 4.4e-59
                      --HHHHHHHHHHHHHHHHSHHHHH...STT-SEEEEEE-S--TT----HHHHHHHHHHSS--SSEEEEEESSEEEEEEEHHHHHTTGGGCTSTT CS
  FACT-Spt16_Nlob   1 idkkafkkRlkklysawkeeeedk...fssvdallvvlGksdeenpykKstalqtWLlGyefpdtlilltkkkiviltskkKaklLeplkekke 91 
                      idk  f+ Rl+++y+awk ++ +    f++v ++++++Gk+de n ++K +a+++WLlGyefp+tl+++t ++++i+t++kKak+Leplk +k 
       EEA22962.1   7 IDKTLFFDRLSTFYNAWKADKRSGagvFGGVGSIIILMGKTDEANAFQKANAMHFWLLGYEFPATLFVFTVDTMYIVTTAKKAKHLEPLKGGK- 99 
                      8*****************766666799*****************************************************************9. PP

                      -.SSEEEEEEE-S-HHHHHHHHHHHHHHHHTTTSEEEE-TT----SHHHHHHHHHHCCCGGG.EEEE-HH CS
  FACT-Spt16_Nlob  92 eekvevellvreKdadenkknfeklieaikeagkkvGvlaKdkseGkfveewkkalkeakke.eevDvsa 160
                         ++ve+lv +Kd+++++k+f k+ie ik+agkkvG+l+Kd+++G+f++ewk+a++e+ k+ eevD+s+
       EEA22962.1 100 ---IPVEILVTSKDPADKAKAFSKCIEVIKAAGKKVGTLPKDNAQGPFADEWKRAFAEELKDeEEVDISP 166
                      ...*********************************************************999*****97 PP

  == domain 2  score: -4.3 bits;  conditional E-value: 3.2
                       ----SHHHHHHHHHHCCCGGGEEEE CS
  FACT-Spt16_Nlob  133 dkseGkfveewkkalkeakkeeevD 157 
                       d+++G+  +e +k  k+++k e+vD
       EEA22962.1  987 DEESGEDWDELEKQAKKKDK-ESVD 1010
                       66777778888888888887.8887 PP

>> Peptidase_M24  Metallopeptidase family M24
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.3   0.0   6.1e-29   2.7e-25       3     209 .]     184     419 ..     182     419 .. 0.83

  Alignments for each domain:
  == domain 1  score: 89.3 bits;  conditional E-value: 6.1e-29
                    HHHHHHHHHHHHHHHH.HHHH....T..TCBHHHHHHHHHHHHHHHTT...............TCEESSSSEEEEGGGGGS.TTTBCSSSB--TTE CS
  Peptidase_M24   3 irkaariasaaleavl.eaik....p..gvterelaaeieattlkrhg...............arglafppivasgenaav.lhytpndrvlkegd 75 
                    +r+aar++s  + + + + +     +  ++t++ laa i+a+ + +                 + ++a+ p+v+sg n+++ l +t+n+++l++  
     EEA22962.1 184 MRNAARACSGLMSEYFvDDMSqlldEgkKITHKSLAARIDAK-IDDSKffnklaklppgfdpqQIDWAYGPVVQSGGNYDLrLTATANSDELHA-G 277
                    999999999999988433333222333367999999999977.54433666777888889999*****************83555999****99.8 PP

                    EEEEEEEEEETTEEEEEEEEEECSSGSHHHHHHHHHHHHHHHHHHHC-STTSBHHHHHHHHHHHHHHT..TBCCGBSSCSEEEESSSSSEEEEEES CS
  Peptidase_M24  76 lvlidagaeydgyasDitrTvlvGkftpeqrelyeavleaqeaaikavkpGvtlseidaaarevlesa..glakffphglGHgvGlevhdegpsvs 169
                    +++  +g++y+ y + i+rT+lv+ +t++q+ +y ++l++ +a+ik ++ Gv +++++++a   ++++   l+ +f +++G g+G+e+ d+ +++ 
     EEA22962.1 278 IIIAGFGIRYKTYSAIIARTYLVD-PTKAQEANYGFLLNVYDAVIKDIRDGVVAKDLYNKAIGMVRAKrpDLENHFVKNVGAGIGIELKDS-NMIL 371
                    ***********************6.8888999**********************************876668999***************9.8887 PP

                    SSTTCSSB--TTBEEEEEEEEEEET.........TTEEEEEBEEEEEES CS
  Peptidase_M24 170 resndgrkleeGmvftiEpgiyfap.........geggvriedtvlvte 209
                    + ++++r+l+ Gm++ i  g+  +          +++++ i dtv v e
     EEA22962.1 372 N-GKNTRTLKSGMTLYISIGLTDVRdtdskdnkkSVYSMVITDTVRVSE 419
                    5.678*****************55434444443344899*****99975 PP

>> Rtt106  Histone chaperone Rttp106-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.6   0.1       0.4   1.8e+03      27      66 ..     709     754 ..     700     758 .. 0.69
   2 !   53.6   0.0   5.1e-18   2.3e-14       5      87 ..     820     902 ..     816     904 .. 0.93

  Alignments for each domain:
  == domain 1  score: -0.6 bits;  conditional E-value: 0.4
      Rtt106  27 kPllfipled....iesvsfeRv...svtsrtfdlvvelkkeeveFs 66 
                 k l+f p+++    i +v+++ +     +++t d+ + ++ +e++F+
  EEA22962.1 709 KHLFFQPCAHelivIIHVHLK-TpilIGKRKTKDVQFIREATEMQFD 754
                 555555555555556666666.3477778999999999999999996 PP

  == domain 2  score: 53.6 bits;  conditional E-value: 5.1e-18
      Rtt106   5 asrkakeGlLyflekgllfgfkkPllfiplediesvsfeRvsvtsrtfdlvvelkk...eeveFsmidqeelegidefvkskgiki 87 
                  +   +++l+++++++++ +++ P+l+++l++ie +++eRv++  ++fdlv++lk+    ++++++i+ e+leg++++++s +i +
  EEA22962.1 820 NR---SNVLIQPTTDAIVQLTEPPFLVVTLNEIEVAHLERVQFGLKNFDLVFVLKDfnrPPIHINTIPVESLEGVKDWLDSVDIPF 902
                 55...899**********************************************88888**********************99976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1019 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1320  (0.0736237); expected 358.6 (0.02)
Passed bias filter:                      541  (0.0301746); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.84u 0.30s 00:00:01.13 Elapsed: 00:00:00.46
# Mc/sec: 6635.74
//
Query:       EEA22963.1  [L=367]
Description: metalloprotease MEP1 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.9e-11   44.1   0.0    4.1e-11   43.0   0.0    1.6  1  Peptidase_M43  Pregnancy-associated plasma protein-A
  ------ inclusion threshold ------
      0.083   13.0   5.1       0.16   12.1   4.9    1.8  1  Reprolysin_5   Metallo-peptidase family M12
       0.19   11.9   1.6        7.6    6.7   0.0    2.9  3  DUF2673        Protein of unknown function (DUF2673)


Domain annotation for each model (and alignments):
>> Peptidase_M43  Pregnancy-associated plasma protein-A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   43.0   0.0   6.9e-15   4.1e-11      69     150 ..     273     359 ..     262     361 .. 0.79

  Alignments for each domain:
  == domain 1  score: 43.0 bits;  conditional E-value: 6.9e-15
  Peptidase_M43  69 sstLthelGhfLgLihtfegg.CerGeg.DkvsDtpsedgkevsavnkdllnCnget..insqnfmdyng..vrasftqdqvdrmvev 150
                      t  he+Gh+ gL htf+ + C  G++ D +sDtp++ ++ ++ +     +C + +      nfmdy+   +++sft++q  rm+++
     EEA22963.1 273 GGTTVHEVGHWHGLLHTFQDQtCAVGASgDYISDTPQQ-STPTEGCPAWKDSCPDLPglDPISNFMDYSSddCYQSFTREQAMRMRSM 359
                    56778*************9877**99867********9.555554444444476554114579*****9667*************975 PP

>> Reprolysin_5  Metallo-peptidase family M12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   4.9   2.7e-05      0.16     140     183 ..     270     304 ..     104     316 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 2.7e-05
  Reprolysin_5 140 atevqvvaHElGHnfGavHDcdsssesqsCslsnstepaggryi 183
                    +   ++ HE+GH  G  H++++    q+C+      +a+g yi
    EEA22963.1 270 YNRGGTTVHEVGHWHGLLHTFQD----QTCAV-----GASGDYI 304
                   55566899**************5....69987.....5777776 PP

>> DUF2673  Protein of unknown function (DUF2673)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.7   0.0    0.0013       7.6       4      47 ..      10      52 ..       7      56 .. 0.91
   2 ?    2.4   0.4     0.029   1.7e+02      32      61 ..     106     136 ..      92     143 .. 0.81
   3 ?   -1.2   0.0      0.37   2.2e+03      16      30 ..     180     194 ..     177     205 .. 0.80

  Alignments for each domain:
  == domain 1  score: 6.7 bits;  conditional E-value: 0.0013
     DUF2673  4 llkilliiafanpvfassmqmpdpasvtttqihamstnaqqdwi 47
                ll i+ i  f+  v+as+ +  +   v t q  + s +aq++w+
  EEA22963.1 10 LLAIVSITVFTGSVIASTRRTGEHEKVNTIQN-SSSEEAQRQWL 52
                789999***********************995.67999*****7 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.029
     DUF2673  32 ttqihamstnaqqdwia.sltanqynmlspd 61 
                  t  h +st  q d ++ s+ + q++ l   
  EEA22963.1 106 ETWFHVVSTSDQADLVTnSMISSQFQYLQQA 136
                 6789**********98548999999888765 PP

  == domain 3  score: -1.2 bits;  conditional E-value: 0.37
     DUF2673  16 pvfassmqmpdpasv 30 
                   f + +++pdpa  
  EEA22963.1 180 IYFQTDLEVPDPAGA 194
                 56889999****975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (367 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       522  (0.0291148); expected 358.6 (0.02)
Passed bias filter:                      405  (0.0225891); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.53u 0.30s 00:00:00.83 Elapsed: 00:00:00.47
# Mc/sec: 2343.29
//
Query:       EEA22964.1  [L=395]
Description: LEM3/CDC50 family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.6e-97  324.6   0.0    6.8e-97  324.3   0.0    1.1  1  CDC50     LEM3 (ligand-effect modulator 3) family / CDC50 fam
  ------ inclusion threshold ------
       0.54   10.3   7.7      0.077   13.0   2.0    2.3  2  DUF3185   Protein of unknown function (DUF3185)


Domain annotation for each model (and alignments):
>> CDC50  LEM3 (ligand-effect modulator 3) family / CDC50 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  324.3   0.0  7.6e-101   6.8e-97       1     280 []      71     371 ..      71     371 .. 0.90

  Alignments for each domain:
  == domain 1  score: 324.3 bits;  conditional E-value: 7.6e-101
       CDC50   1 llvasksvkeleidYtsecataaesek.............................easkekktCtvqftvpedlkapvyvyYeLtnfyQnhrryvkSr 70 
                 ll+as++v+e+ idYt +c+t a+ ++                             ++ ++++ C++ f++pe l +pv++yY+LtnfyQnhr+yv+S+
  EEA22964.1  71 LLWASEQVQEIIIDYT-DCDTLAPLSStaalpsgrvtssfkssaqtsvttwqrnetDEATKTTGCSLFFDIPEPLGPPVFLYYKLTNFYQNHRKYVQSL 168
                 689*************.99988877778899999999999999999999999998888889999*********************************** PP

       CDC50  71 ddsqlkgkaks.s.lksssssdCepletakekkekkkiiyPCGliAnslFNDtfslvee.ssskltkvnltkkgIawksdkekkfknktkyealeevvk 166
                 d +ql+gk+++ + ++  +s +C+pl+t+  +    k++yPCGliAnslFND++s     +   +++ n+t+kgIaw+sdk +  k+ tky+   +vv+
  EEA22964.1 169 DTDQLQGKVVDnAtIS--GS-TCDPLTTDPATG---KAYYPCGLIANSLFNDSISSPVLvN---EETYNMTDKGIAWPSDK-EIIKT-TKYNY-WQVVP 255
                 *********7744343..34.6****8766644...68****************4444422...46789************.67774.77765.9**** PP

       CDC50 167 PpnWakk.pe..eteipelkenedfivWmrtAalptFrKlyrrindeedLkagtyevdiennfpvksFkGtKsivlsttswlGgknpflgiaYlvvGgi 262
                 PpnW+ k pe  +++ p+l ++e+f+vWmrtA+lptF+Kl+rr nd++ ++ag+y++di+++f+v++++GtKsi++st++++Ggkn+f+giaY+vvGg+
  EEA22964.1 256 PPNWRVKyPEytAENFPDLGNDEAFMVWMRTAGLPTFSKLARR-NDTTAMPAGQYRLDIQSSFNVTEYGGTKSIMISTRTVMGGKNSFMGIAYIVVGGV 353
                 ****99985567999****************************.999**************************************************** PP

       CDC50 263 clvlaivflvthlikprk 280
                 c++++++f++++li+prk
  EEA22964.1 354 CVLIGVLFTAANLIRPRK 371
                 ****************97 PP

>> DUF3185  Protein of unknown function (DUF3185)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   0.3      0.19   1.7e+03       2      18 ..      59      75 ..      58      82 .. 0.80
   2 ?   13.0   2.0   8.6e-06     0.077      22      57 ..     325     360 ..     319     361 .. 0.89

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 0.19
     DUF3185  2 iiGiiLlvaGivLlvfG 18
                +iG i+  +G vLl+  
  EEA22964.1 59 VIGAIFAPLGGVLLWAS 75
                58899999999999865 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 8.6e-06
     DUF3185  22 sdSlgsqvseaftGsttdktlllligGgvaaivGlv 57 
                 ++S++ + ++++ G+++  ++++++ Ggv++++G++
  EEA22964.1 325 TKSIMISTRTVMGGKNSFMGIAYIVVGGVCVLIGVL 360
                 6788889999999*********************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (395 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       576  (0.0321267); expected 358.6 (0.02)
Passed bias filter:                      474  (0.0264376); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.53u 0.28s 00:00:00.81 Elapsed: 00:00:00.44
# Mc/sec: 2708.53
//
Query:       EEA22965.1  [L=389]
Description: SWIRM domain protein Fun19, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.6e-11   42.9   0.0    8.7e-11   42.0   0.0    1.4  1  SWIRM     SWIRM domain


Domain annotation for each model (and alignments):
>> SWIRM  SWIRM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.0   0.0   4.9e-15   8.7e-11      10      87 ..     309     378 ..     304     380 .. 0.93

  Alignments for each domain:
  == domain 1  score: 42.0 bits;  conditional E-value: 4.9e-15
       SWIRM  10 slhpiEkellselfngkdktpeeYlkiRnkiialyrenp..keyltvteaqkalkrrrltgidvnllsrihefLerwGlI 87 
                  l p E++l+++l+     ++++Yl ++++i++++ +     +++++t+aq+a+k      idvn++s+++++++r+G++
  EEA22965.1 309 LLDPAEVNLAATLR----LSCATYLCSKRRIFEARVKALsiGKEFRKTDAQQACK------IDVNKASKLWTAYDRVGWF 378
                 6899**********....******************98666899***********......9*****************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (389 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       487  (0.0271627); expected 358.6 (0.02)
Passed bias filter:                      342  (0.0190752); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.23s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 2857.75
//
Query:       EEA22966.1  [L=374]
Description: nucleolar RNAse III, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-14   54.7   0.0    2.9e-14   53.3   0.0    1.8  1  Ribonucleas_3_3  Ribonuclease-III-like
    6.9e-14   52.4   0.0    1.9e-13   50.9   0.0    1.8  1  Ribonuclease_3   Ribonuclease III domain


Domain annotation for each model (and alignments):
>> Ribonucleas_3_3  Ribonuclease-III-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   53.3   0.0   3.2e-18   2.9e-14      16     127 ..     142     258 ..     122     259 .. 0.87

  Alignments for each domain:
  == domain 1  score: 53.3 bits;  conditional E-value: 3.2e-18
  Ribonucleas_3_3  16 ngrkghNerLefLGdavLklsvseyllekaek.degeltklraslvseeslaeiAkelgLgkvlrlrkgeee.tegsgrekvladaleAliGAi 107
                      +g+++++ rLe+LGda ++++ ++++  +++  + g+++++r++lv++e+la +A++ g++k + ++ +ee+  + ++  k+++d++eA ++A+
       EEA22966.1 142 EGMEQNYDRLEVLGDAYVEVIATRLIWDHFKDmPAGRMSQVREDLVKNETLAGFASQYGFDKRVSVSAPEEQkAQPKRWLKIRGDVFEAYVAAV 235
                      5899**********************999766599*******************************776666366677789************* PP

  Ribonucleas_3_3 108 yl...dkgaevaqefveekilkk 127
                       l   d+g++ ++++ +e +l++
       EEA22966.1 236 VLsnpDHGFDIVEQWLRELWLPR 258
                      99666799999999999888776 PP

>> Ribonuclease_3  Ribonuclease III domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.9   0.0   2.1e-17   1.9e-13       1     104 [.     149     239 ..     149     240 .. 0.88

  Alignments for each domain:
  == domain 1  score: 50.9 bits;  conditional E-value: 2.1e-17
                     HHHHHHHHHHHHHHHHHHHHHHCTTSSHHHHHHHHHHHTSHHHHHHHHHCTTCHCCHCHH..............HHCCSTTCHCTSHHHHHHHHH CS
  Ribonuclease_3   1 erLeflGDavlklaittylfetypdahegrlsklrsklvsnenlarlakklglpkflrasefdpprnwlppgyklsddekedddadkvladvvEA 95 
                     +rLe lGDa++++++t+ ++++++d   gr+s++r  lv+ne+la +a ++g++k++ +s         p+  + + ++k+     k+ +dv+EA
      EEA22966.1 149 DRLEVLGDAYVEVIATRLIWDHFKDMPAGRMSQVREDLVKNETLAGFASQYGFDKRVSVSA--------PE--EQKAQPKR---WLKIRGDVFEA 230
                     59********************************************************532........11..13344444...8899******* PP

                     HHHHHHHHC CS
  Ribonuclease_3  96 liGaiylds 104
                     +++a++l++
      EEA22966.1 231 YVAAVVLSN 239
                     *****9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (374 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       563  (0.0314016); expected 358.6 (0.02)
Passed bias filter:                      388  (0.0216409); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.26s 00:00:00.75 Elapsed: 00:00:00.43
# Mc/sec: 2618.84
//
Query:       EEA22967.1  [L=296]
Description: nucleolar RNAse III, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.1e-14   54.7   0.0    1.7e-14   54.1   0.0    1.4  1  Ribonucleas_3_3  Ribonuclease-III-like
    5.1e-14   52.8   0.0    1.2e-13   51.5   0.0    1.7  1  Ribonuclease_3   Ribonuclease III domain


Domain annotation for each model (and alignments):
>> Ribonucleas_3_3  Ribonuclease-III-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.1   0.0   1.9e-18   1.7e-14      16     127 ..      64     180 ..      44     181 .. 0.87

  Alignments for each domain:
  == domain 1  score: 54.1 bits;  conditional E-value: 1.9e-18
  Ribonucleas_3_3  16 ngrkghNerLefLGdavLklsvseyllekaek.degeltklraslvseeslaeiAkelgLgkvlrlrkgeee.tegsgrekvladaleAliGAi 107
                      +g+++++ rLe+LGda ++++ ++++  +++  + g+++++r++lv++e+la +A++ g++k + ++ +ee+  + ++  k+++d++eA ++A+
       EEA22967.1  64 EGMEQNYDRLEVLGDAYVEVIATRLIWDHFKDmPAGRMSQVREDLVKNETLAGFASQYGFDKRVSVSAPEEQkAQPKRWLKIRGDVFEAYVAAV 157
                      5899**********************999766599*******************************776666366677789************* PP

  Ribonucleas_3_3 108 yl...dkgaevaqefveekilkk 127
                       l   d+g++ ++++ +e +l++
       EEA22967.1 158 VLsnpDHGFDIVEQWLRELWLPR 180
                      99666799999999999888776 PP

>> Ribonuclease_3  Ribonuclease III domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.5   0.0   1.4e-17   1.2e-13       1     104 [.      71     161 ..      71     162 .. 0.88

  Alignments for each domain:
  == domain 1  score: 51.5 bits;  conditional E-value: 1.4e-17
                     HHHHHHHHHHHHHHHHHHHHHHCTTSSHHHHHHHHHHHTSHHHHHHHHHCTTCHCCHCHH..............HHCCSTTCHCTSHHHHHHHHH CS
  Ribonuclease_3   1 erLeflGDavlklaittylfetypdahegrlsklrsklvsnenlarlakklglpkflrasefdpprnwlppgyklsddekedddadkvladvvEA 95 
                     +rLe lGDa++++++t+ ++++++d   gr+s++r  lv+ne+la +a ++g++k++ +s         p+  + + ++k+     k+ +dv+EA
      EEA22967.1  71 DRLEVLGDAYVEVIATRLIWDHFKDMPAGRMSQVREDLVKNETLAGFASQYGFDKRVSVSA--------PE--EQKAQPKR---WLKIRGDVFEA 152
                     59********************************************************532........11..13344444...8899******* PP

                     HHHHHHHHC CS
  Ribonuclease_3  96 liGaiylds 104
                     +++a++l++
      EEA22967.1 153 YVAAVVLSN 161
                     *****9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (296 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       368  (0.0205254); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.24s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2094.48
//
Query:       EEA22968.1  [L=108]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.9e-30  103.6   0.1      6e-30  103.3   0.1    1.1  1  MRP-S33   Mitochondrial ribosomal subunit S27


Domain annotation for each model (and alignments):
>> MRP-S33  Mitochondrial ribosomal subunit S27
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  103.3   0.1   3.3e-34     6e-30       1      88 []       6      94 ..       6      94 .. 0.98

  Alignments for each domain:
  == domain 1  score: 103.3 bits;  conditional E-value: 3.3e-34
     MRP-S33  1 arllelaklsarIFgevynptnlrtgsKvlrkrlkgplladYYpprivsfkqlkkllrel.lkfrDeaeefrlemvalrkrRGKgapkK 88
                +r+l+l+k ++rIF +++np++lr g+K+lr+rl+gp+la+YYp+++vsf++l+ +++ l l+++De +++r+e ++  k+RGKg pkK
  EEA22968.1  6 SRILDLVKTQCRIFATTFNPQRLRLGNKILRQRLRGPALAAYYPRKTVSFRDLQDTYKPLgLETFDEGQDDREEAIQIAKLRGKGRPKK 94
                5899******************************************************99899*************************9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (108 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       376  (0.0209716); expected 358.6 (0.02)
Passed bias filter:                      209  (0.0116571); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.37u 0.26s 00:00:00.63 Elapsed: 00:00:00.41
# Mc/sec: 782.03
//
Query:       EEA22969.1  [L=431]
Description: ankyrin repeat-containing protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    3.8e-19   69.1   0.0    9.7e-05   22.9   0.0    4.8  5  Ank_2       Ankyrin repeats (3 copies)
    9.3e-19   65.6   8.1       0.01   16.3   0.0    9.8 11  Ank_3       Ankyrin repeat
      5e-18   65.2   1.0      0.079   13.6   0.0    7.4  8  Ank_4       Ankyrin repeats (many copies)
    3.8e-17   61.9   2.1      0.008   16.6   0.1    9.1 10  Ank         Ankyrin repeat
    2.3e-12   46.9   4.8     0.0055   17.0   0.0    5.7  6  Ank_5       Ankyrin repeats (many copies)
    0.00015   21.6   1.3    0.00015   21.6   1.3    1.9  2  F-box-like  F-box-like
  ------ inclusion threshold ------
      0.015   15.2   0.4      0.036   14.0   0.4    1.6  1  F-box       F-box domain


Domain annotation for each model (and alignments):
>> Ank_2  Ankyrin repeats (3 copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.2   0.0      0.11   2.8e+02      43      81 ..      35      79 ..      13      81 .. 0.73
   2 !   22.9   0.0   3.8e-08   9.7e-05       3      76 ..      57     159 ..      55     168 .. 0.70
   3 !   21.1   0.0   1.4e-07   0.00036       4      76 ..     175     258 ..     172     262 .. 0.69
   4 !    9.2   0.0   0.00072       1.9      11      61 ..     280     334 ..     274     339 .. 0.76
   5 !    9.4   0.0   0.00063       1.6      11      46 ..     388     426 ..     376     430 .. 0.60

  Alignments for each domain:
  == domain 1  score: 2.2 bits;  conditional E-value: 0.11
       Ank_2 43 klLleh......adndgrtpLhyAarsghleivklLlekgadinl 81
                k Ll         dn  +  L++++  g++ +v+ +l +ga++n+
  EEA22969.1 35 KVLLPSlyqrhvRDNRLQLGLFWSVATGNEAAVNHFLHYGANVNA 79
                666653333344446666779999999999999999988999985 PP

  == domain 2  score: 22.9 bits;  conditional E-value: 3.8e-08
       Ank_2   3 lAakngnlelvklLl.egadpn......k............ngktaLhyAakngnleivklLleh...ad.......ndgrtpLhyAarsghleivklL 72 
                 + +  gn  +v+++l +ga++n                     +t+L +Aa  gn+ iv lLl+h   +d        + + +   A  sgh+ +v+lL
  EEA22969.1  57 WSVATGNEAAVNHFLhYGANVNacigiiPirrasisfqpwfSVQTPLSIAANIGNNMIVDLLLKHganVDgfpspgwGTTQPAVLDALLSGHESTVRLL 155
                 55666767788888888877766544440444456666776669**********9888******99553366555332244589*************** PP

       Ank_2  73 lekg 76 
                 l ++
  EEA22969.1 156 LMHK 159
                 9654 PP

  == domain 3  score: 21.1 bits;  conditional E-value: 1.4e-07
       Ank_2   4 Aak.ngnlelvklLl.egadpn.k.ngktaLhyAakng..nleivklLleh.ad...ndgr..tpLhyAarsghleivklLlekg 76 
                 +a  +g  +l+klL+ +gad+n   +g  +L  ++++   ++eiv++Ll++ ad    +g+    L  A+ +g + +++lLl++g
  EEA22969.1 175 CAIaKGEISLLKLLVeFGADLNiPwQGAYPLNRSVSSPklSTEIVRFLLDNgADiglTNGNpgILLDQAI-HGTIGTLRLLLDRG 258
                 4452576789999999999998658899999988886433668999999888555553344212468888.78888888888776 PP

  == domain 4  score: 9.2 bits;  conditional E-value: 0.00072
       Ank_2  11 elvklLl.egadpnkngktaLhyAakngnleivklLleh...ad...ndgrtpLhyAa 61 
                 e+v+l+l +g+ pn   +  L + ++++  +i++l+++    ++     g t Lh A+
  EEA22969.1 280 ETVHLFLeYGYAPN---LETLSIVVRAQRGDILQLFIDRgvdLNmkgTRGLTLLHEAV 334
                 68889999999998...77777777776669999999977453355666999999998 PP

  == domain 5  score: 9.4 bits;  conditional E-value: 0.00063
       Ank_2  11 elvklLl.egadpn..k.ngktaLhyAakngnleivklLl 46 
                 ++v+ L+  gad+n  + ng+t+L +A +  +l i ++L+
  EEA22969.1 388 KIVRCLVrGGADLNalDaNGRTPLALAREF-HLAIQQILI 426
                 367777766677775535777777766554.344444444 PP

>> Ank_3  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0      0.38   9.8e+02       6      31 .]      55      79 ..      52      79 .. 0.83
   2 !   16.3   0.0   3.9e-06      0.01       3      30 ..     100     126 ..     100     127 .. 0.95
   3 ?    0.3   0.0      0.66   1.7e+03       9      25 ..     143     159 ..     142     163 .. 0.82
   4 !    8.6   0.1    0.0013       3.3       8      31 .]     175     197 ..     172     197 .. 0.91
   5 !   12.2   0.0   8.3e-05      0.21       2      29 ..     201     229 ..     200     231 .. 0.88
   6 ?   -1.7   0.0         3   7.6e+03      14      27 ..     248     259 ..     239     261 .. 0.66
   7 ?   -0.7   0.0       1.3   3.4e+03      16      30 ..     280     293 ..     274     294 .. 0.74
   8 !    9.6   0.0   0.00059       1.5       6      30 ..     297     320 ..     297     321 .. 0.93
   9 ?    3.7   0.0     0.049   1.2e+02       2      12 ..     326     336 ..     325     346 .. 0.84
  10 ?    5.6   0.0     0.012        31      14      31 .]     386     402 ..     376     402 .. 0.74
  11 ?   -0.7   0.0       1.4   3.5e+03       1       9 [.     406     414 ..     406     421 .. 0.88

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.38
       Ank_3  6 LhlAarsgnleivkfLlenkgadvna 31
                L++ +  gn + v  +l  +ga+vna
  EEA22969.1 55 LFWSVATGNEAAVNHFLH-YGANVNA 79
                667777788888999999.9****96 PP

  == domain 2  score: 16.3 bits;  conditional E-value: 3.9e-06
       Ank_3   3 etpLhlAarsgnleivkfLlenkgadvn 30 
                 +tpL +Aa  gn  iv++Ll+ +ga+v+
  EEA22969.1 100 QTPLSIAANIGNNMIVDLLLK-HGANVD 126
                 7********************.9***97 PP

  == domain 3  score: 0.3 bits;  conditional E-value: 0.66
       Ank_3   9 AarsgnleivkfLlenk 25 
                 A++sg+ + v++Ll +k
  EEA22969.1 143 ALLSGHESTVRLLLMHK 159
                 788999999*****953 PP

  == domain 4  score: 8.6 bits;  conditional E-value: 0.0013
       Ank_3   8 lAarsgnleivkfLlenkgadvna 31 
                 +A+  g ++++k+L+e +gad+n+
  EEA22969.1 175 CAIAKGEISLLKLLVE-FGADLNI 197
                 799999999*******.*****97 PP

  == domain 5  score: 12.2 bits;  conditional E-value: 8.3e-05
       Ank_3   2 GetpLhlAarsgnl..eivkfLlenkgadv 29 
                 G +pL + ++s +l  eiv+fLl+ +gad+
  EEA22969.1 201 GAYPLNRSVSSPKLstEIVRFLLD-NGADI 229
                 789***********645*******.8***8 PP

  == domain 6  score: -1.7 bits;  conditional E-value: 3
       Ank_3  14 nleivkfLlenkga 27 
                   + +++Ll+ +g+
  EEA22969.1 248 IGT-LRLLLD-RGV 259
                 334.999**9.886 PP

  == domain 7  score: -0.7 bits;  conditional E-value: 1.3
       Ank_3  16 eivkfLlenkgadvn 30 
                 e v+++le +g  +n
  EEA22969.1 280 ETVHLFLE-YGYAPN 293
                 3599****.999988 PP

  == domain 8  score: 9.6 bits;  conditional E-value: 0.00059
       Ank_3   6 LhlAarsgnleivkfLlenkgadvn 30 
                 L +++r+++ +i++++++ +g+d+n
  EEA22969.1 297 LSIVVRAQRGDILQLFID-RGVDLN 320
                 6799**************.*****9 PP

  == domain 9  score: 3.7 bits;  conditional E-value: 0.049
       Ank_3   2 GetpLhlAars 12 
                 G t+Lh+A++ 
  EEA22969.1 326 GLTLLHEAVLR 336
                 89*****9986 PP

  == domain 10  score: 5.6 bits;  conditional E-value: 0.012
       Ank_3  14 nleivkfLlenkgadvna 31 
                 + +iv+ L++  gad+na
  EEA22969.1 386 PEKIVRCLVR-GGADLNA 402
                 2349******.9****96 PP

  == domain 11  score: -0.7 bits;  conditional E-value: 1.4
       Ank_3   1 nGetpLhlA 9  
                 nG+tpL lA
  EEA22969.1 406 NGRTPLALA 414
                 79****887 PP

>> Ank_4  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   0.0      0.63   1.6e+03      12      30 ..      62      80 ..      53      91 .. 0.68
   2 !   13.6   0.0   3.1e-05     0.079       3      55 .]     101     156 ..     100     156 .. 0.92
   3 !   10.4   0.0    0.0003      0.77       8      30 ..     176     198 ..     171     211 .. 0.79
   4 !    8.2   0.0    0.0015         4      14      42 ..     216     243 ..     215     255 .. 0.75
   5 ?    2.3   0.0       0.1   2.6e+02       5      25 ..     239     259 ..     236     267 .. 0.85
   6 ?   -2.5   0.0       3.4   8.8e+03      14      27 ..     279     292 ..     276     296 .. 0.80
   7 !   13.2   0.0   4.2e-05      0.11       8      45 ..     300     336 ..     293     337 .. 0.83
   8 !    8.1   0.0    0.0016         4      11      39 ..     384     411 ..     376     416 .. 0.85

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.63
       Ank_4 12 grlelvrlLlekgadinaq 30
                g++ +v   l +ga++na+
  EEA22969.1 62 GNEAAVNHFLHYGANVNAC 80
                6666666455589999999 PP

  == domain 2  score: 13.6 bits;  conditional E-value: 3.1e-05
       Ank_4   3 taLhyaaisgrlelvrlLlekgadinaq.dnrsGet..alhiAakrgnveilklLl 55 
                 t+L  aa+ g+  +v+lLl +ga+++   +++ G t  a+  A++ g+ + ++lLl
  EEA22969.1 101 TPLSIAANIGNNMIVDLLLKHGANVDGFpSPGWGTTqpAVLDALLSGHESTVRLLL 156
                 6888999999******************77899888889999************98 PP

  == domain 3  score: 10.4 bits;  conditional E-value: 0.0003
       Ank_4   8 aaisgrlelvrlLlekgadinaq 30 
                 a+++g + l++lL+e+gad+n  
  EEA22969.1 176 AIAKGEISLLKLLVEFGADLNIP 198
                 788****************9984 PP

  == domain 4  score: 8.2 bits;  conditional E-value: 0.0015
       Ank_4  14 lelvrlLlekgadinaqdnrsGetalhiA 42 
                 +e+vr+Ll++gadi  + n++   +l+ A
  EEA22969.1 216 TEIVRFLLDNGADIGLT-NGNPGILLDQA 243
                 689************99.66533455555 PP

  == domain 5  score: 2.3 bits;  conditional E-value: 0.1
       Ank_4   5 LhyaaisgrlelvrlLlekga 25 
                 L  +ai+g + ++rlLl++g+
  EEA22969.1 239 LLDQAIHGTIGTLRLLLDRGV 259
                 677899***********9986 PP

  == domain 6  score: -2.5 bits;  conditional E-value: 3.4
       Ank_4  14 lelvrlLlekgadi 27 
                 le+v+l le+g  +
  EEA22969.1 279 LETVHLFLEYGYAP 292
                 79999999998655 PP

  == domain 7  score: 13.2 bits;  conditional E-value: 4.2e-05
       Ank_4   8 aaisgrlelvrlLlekgadinaqdnrsGetalhiAakr 45 
                  + ++r ++++l +++g+d+n+    +G+t+lh A++r
  EEA22969.1 300 VVRAQRGDILQLFIDRGVDLNMK-GTRGLTLLHEAVLR 336
                 555677789*************9.999********986 PP

  == domain 8  score: 8.1 bits;  conditional E-value: 0.0016
       Ank_4  11 sgrlelvrlLlek.gadinaqdnrsGetal 39 
                 + ++++vr L+ + gad+na  +++G+t+l
  EEA22969.1 384 DAPEKIVRCLV-RgGADLNAL-DANGRTPL 411
                 56788899999.659*****9.*******9 PP

>> Ank  Ankyrin repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.0      0.04     1e+02      13      29 ..      62      79 ..      55      81 .. 0.77
   2 !   16.6   0.1   3.1e-06     0.008       4      28 ..     101     126 ..     100     126 .. 0.91
   3 ?    0.2   0.0      0.47   1.2e+03      12      24 ..     146     159 ..     139     167 .. 0.76
   4 ?    4.5   0.1     0.021        53      15      29 ..     182     197 ..     174     198 .. 0.75
   5 !    7.0   0.0    0.0032       8.3       5      30 ..     204     232 ..     200     233 .. 0.67
   6 ?   -3.5   0.0       6.9   1.8e+04      11      24 ..     247     258 ..     243     259 .. 0.68
   7 ?   -1.5   0.0       1.6   4.1e+03      17      29 ..     281     294 ..     277     299 .. 0.77
   8 ?    4.1   0.0     0.028        72      11      30 ..     305     322 ..     283     323 .. 0.82
   9 !   11.6   0.0   0.00012      0.31       2      31 ..     326     404 ..     325     405 .. 0.76
  10 ?    1.9   0.0      0.14   3.6e+02       1      10 [.     406     415 ..     406     429 .. 0.67

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.04
                TTHHHHHHHHT.TTSTTC CS
         Ank 13 gkkriiklLLh.GAnlna 29
                g++  +  +Lh GAn+na
  EEA22969.1 62 GNEAAVNHFLHyGANVNA 79
                555567789955*****9 PP

  == domain 2  score: 16.6 bits;  conditional E-value: 3.1e-06
                 BHHHHHHHHTTHHHHHHHH.TTTSTT CS
         Ank   4 TPLHlAatngkkriiklLL.hGAnln 28 
                 TPL +Aa++g+  i+ lLL hGAn++
  EEA22969.1 101 TPLSIAANIGNNMIVDLLLkHGANVD 126
                 *******888888***********96 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.47
                 HTTHHHHHHHH.TT CS
         Ank  12 ngkkriiklLL.hG 24 
                  g+++ ++lLL h 
  EEA22969.1 146 SGHESTVRLLLmHK 159
                 488999****9885 PP

  == domain 4  score: 4.5 bits;  conditional E-value: 0.021
                 HHHHHHHH.TTTSTTC CS
         Ank  15 kriiklLL.hGAnlna 29 
                  + +klL+  GA+ln+
  EEA22969.1 182 ISLLKLLVeFGADLNI 197
                 5588999977*****7 PP

  == domain 5  score: 7.0 bits;  conditional E-value: 0.0032
                 HHHHHHHHTT..HHHHHHHH.TTTSTTCB CS
         Ank   5 PLHlAatngk..kriiklLL.hGAnlnal 30 
                 PL + ++  k  ++i+++LL +GA++ ++
  EEA22969.1 204 PLNRSVSSPKlsTEIVRFLLdNGADIGLT 232
                 55554433334688******88***8665 PP

  == domain 6  score: -3.5 bits;  conditional E-value: 6.9
                 HHTTHHHHHHHH.TT CS
         Ank  11 tngkkriiklLL.hG 24 
                 t+g    ++lLL +G
  EEA22969.1 247 TIG---TLRLLLdRG 258
                 567...789999445 PP

  == domain 7  score: -1.5 bits;  conditional E-value: 1.6
                 HHHHHH.TT.TSTTC CS
         Ank  17 iiklLL.hG.Anlna 29 
                  ++l+L +G A +n+
  EEA22969.1 281 TVHLFLeYGyA-PNL 294
                 799***88987.775 PP

  == domain 8  score: 4.1 bits;  conditional E-value: 0.028
                 HHTTHHHHHHHH.TTTSTTCB CS
         Ank  11 tngkkriiklLL.hGAnlnal 30 
                 +++   i++l++ +G +ln++
  EEA22969.1 305 RGD---ILQLFIdRGVDLNMK 322
                 455...******779***986 PP

  == domain 9  score: 11.6 bits;  conditional E-value: 0.00012
                 SBBHHHHH..........................................HHHTT......HHHHHHHH.TTTSTTCBT CS
         Ank   2 GnTPLHlA..........................................atngk......kriiklLL.hGAnlnald 31 
                 G T LH A                                          ++n++      + i++ L+  GA+lnald
  EEA22969.1 326 GLTLLHEAvlrcippeppvrmvgraavcrrpgrenlvrkiepvlqrvsptCMNDNveedapEKIVRCLVrGGADLNALD 404
                 78888887777777777777777777777777777777777776666666788889999999*******447*****99 PP

  == domain 10  score: 1.9 bits;  conditional E-value: 0.14
                 TSBBHHHHHH CS
         Ank   1 dGnTPLHlAa 10 
                 +G+TPL lA 
  EEA22969.1 406 NGRTPLALAR 415
                 7*****9963 PP

>> Ank_5  Ankyrin repeats (many copies)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.1       3.3   8.6e+03      18      44 ..      53      79 ..      44      80 .. 0.63
   2 !    6.1   0.0    0.0057        15      18      42 ..     101     125 ..      96     128 .. 0.91
   3 ?    1.3   0.0      0.18   4.7e+02      23      44 ..     176     197 ..     174     198 .. 0.86
   4 !   10.2   0.0   0.00028      0.73      28      47 ..     215     234 ..     202     240 .. 0.92
   5 !   17.0   0.0   2.2e-06    0.0055      18      56 .]     295     333 ..     286     333 .. 0.89
   6 !    8.8   0.1   0.00078         2      32      56 .]     390     414 ..     388     414 .. 0.86

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 3.3
       Ank_5 18 tpLhvAakygaadvvrlLlargadlnl 44
                + L +++  g+   v+ +l +ga+ n+
  EEA22969.1 53 LGLFWSVATGNEAAVNHFLHYGANVNA 79
                555566666666667777778888776 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.0057
       Ank_5  18 tpLhvAakygaadvvrlLlargadl 42 
                 tpL +Aa+ g+  +v lLl++ga+ 
  EEA22969.1 101 TPLSIAANIGNNMIVDLLLKHGANV 125
                 9*********************986 PP

  == domain 3  score: 1.3 bits;  conditional E-value: 0.18
       Ank_5  23 AakygaadvvrlLlargadlnl 44 
                 A+ +g  ++++lL+++gadln+
  EEA22969.1 176 AIAKGEISLLKLLVEFGADLNI 197
                 77788889999999******97 PP

  == domain 4  score: 10.2 bits;  conditional E-value: 0.00028
       Ank_5  28 aadvvrlLlargadlnltds 47 
                 + ++vr+Ll++gad++lt++
  EEA22969.1 215 STEIVRFLLDNGADIGLTNG 234
                 579***************97 PP

  == domain 5  score: 17.0 bits;  conditional E-value: 2.2e-06
       Ank_5  18 tpLhvAakygaadvvrlLlargadlnltdsrGltaldlA 56 
                 + L + +++++ d+++l+++rg+dln++  rGlt+l+ A
  EEA22969.1 295 ETLSIVVRAQRGDILQLFIDRGVDLNMKGTRGLTLLHEA 333
                 6799999****************************9866 PP

  == domain 6  score: 8.8 bits;  conditional E-value: 0.00078
       Ank_5  32 vrlLlargadlnltdsrGltaldlA 56 
                 vr L+  gadln+ d++G+t+l lA
  EEA22969.1 390 VRCLVRGGADLNALDANGRTPLALA 414
                 66677899*************9987 PP

>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.6   1.3   5.9e-08   0.00015       2      46 ..       4      46 ..       3      48 .. 0.93
   2 ?   -1.7   0.1       1.1   2.8e+03      25      30 ..     350     355 ..     334     355 .. 0.77

  Alignments for each domain:
  == domain 1  score: 21.6 bits;  conditional E-value: 5.9e-08
  F-box-like  2 srLPdEiLlqIFsyLppsdLlrlalVCrrWrrvaldtplLWrrlv 46
                + LP+E+ l I s Lp s L+ l +V r+ + v    p+L++r v
  EEA22969.1  4 LELPTELVLLIASSLPESALAHLLQVHRSLYKVL--LPSLYQRHV 46
                68*******************************9..67****976 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 1.1
  F-box-like  25 alVCrr 30 
                 a+VCrr
  EEA22969.1 350 AAVCRR 355
                 79**98 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.4   1.4e-05     0.036       1      36 [.       1      36 [.       1      38 [. 0.95

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1.4e-05
                -HHHHS-HHHHHHHHHTS-HHHHHHHCTT-HHHHHH CS
       F-box  1 ftlsrLPsevlrhILerLplsdllalrrVSkgwril 36
                +tl++LP e+++ I ++Lp s l  l +V ++++++
  EEA22969.1  1 MTLLELPTELVLLIASSLPESALAHLLQVHRSLYKV 36
                79******************************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (431 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       193  (0.0107647); expected 358.6 (0.02)
Passed bias filter:                      191  (0.0106531); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.41
# Mc/sec: 3173.14
//
Query:       EEA22970.1  [L=342]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.2e-12   48.8   0.0    1.8e-12   48.2   0.0    1.4  1  Metallophos    Calcineurin-like phosphoesterase
    3.1e-08   34.0   0.0    4.9e-08   33.3   0.0    1.3  1  Metallophos_2  Calcineurin-like phosphoesterase superfamily d
  ------ inclusion threshold ------
      0.012   15.0   0.0      0.018   14.4   0.0    1.2  1  Metallophos_3  Metallophosphoesterase, calcineurin superfamil


Domain annotation for each model (and alignments):
>> Metallophos  Calcineurin-like phosphoesterase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.2   0.0   2.9e-16   1.8e-12       2     128 ..     102     245 ..     101     321 .. 0.74

  Alignments for each domain:
  == domain 1  score: 48.2 bits;  conditional E-value: 2.9e-16
                  EEEEEESBTBTTCCTHHHHHHHHHHHHHHHTTESEEEEESTSSSSSHHHHHHHHHHHHHHHHTSEEEEEC-TTS........................ CS
  Metallophos   2 rilvigDlHlalgggqlddllkllddllreekpdlvllaGDlvdrgdlekellellaalvkypipvylllGNHe........................ 75 
                  r+++igD+H     g++d+l++ll+++    ++d ++++GD ++ g+ + ++++l ++l++      ++ GNHe                        
   EEA22970.1 102 RLVFIGDVH-----GCFDELEELLRKISLT-RRDHLIFTGDMINKGPQSGKVVDLARQLGA-----SCVQGNHEdrillirtdlqsrgildsgsvnay 188
                  789******.....*************666.9*****************************.....9*******999999998888865555555444 PP

                  ...CHHHHHHHHHHHHHHHHHHHEHHHCEEETSEEEEEETTE...EEEEEEESE.CEEE...T CS
  Metallophos  76 ...gfeeellnkygylgifsepwrsdaevfnnlplaslgsgs...lkvlllhGg.spel...l 128
                     +++ +  ++ ++l+ +++ w ++       p +  +++     +v+++hGg  p     +
   EEA22970.1 189 dlpAYDWNDRQLARSLADDQAAWLQE------CPAILKIGQVkdmGEVVVVHGGlHPAVpleQ 245
                  44222223333333333334444443......3333333333467789999999533334442 PP

>> Metallophos_2  Calcineurin-like phosphoesterase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.3   0.0   8.3e-12   4.9e-08       3     100 ..     103     236 ..     102     260 .. 0.72

  Alignments for each domain:
  == domain 1  score: 33.3 bits;  conditional E-value: 8.3e-12
  Metallophos_2   3 laiiSDlHsnldaleavlealkevgvdaiihaGDl..eeeepevleellelapvlaVrGNnD................................ee 64 
                    l++i D+H+ +d+le++l++++ ++ d++i++GD+  ++ +   + +l +++    V+GN++                                ++
     EEA22970.1 103 LVFIGDVHGCFDELEELLRKISLTRRDHLIFTGDMinKGPQSGKVVDLARQLGASCVQGNHEdrillirtdlqsrgildsgsvnaydlpaydwnDR 198
                    789*******************************974444444999999999**********8888888888888777777777777776655333 PP

  Metallophos_2  65 vveedvlreaaelgtdlpeeaelelagek....vlliHgd 100
                     +++ +++ +a + ++ p  a l+++++k    v ++Hg 
     EEA22970.1 199 QLARSLADDQAAWLQECP--AILKIGQVKdmgeVVVVHGG 236
                    366666666666666664..44444444444458888876 PP

>> Metallophos_3  Metallophosphoesterase, calcineurin superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.4   0.0     3e-06     0.018       5      46 ..     100     141 ..      97     168 .. 0.90

  Alignments for each domain:
  == domain 1  score: 14.4 bits;  conditional E-value: 3e-06
                    --EEEEEE--TT-GGGHHHHHHHHHHH--SEEEEES-----H CS
  Metallophos_3   5 vrkvlaisdlkgevellerlveviedkdpDllvlvGdlvkae 46 
                     r+++ i d++g ++ le+l+++i+    D l+++Gd+++++
     EEA22970.1 100 RRRLVFIGDVHGCFDELEELLRKISLTRRDHLIFTGDMINKG 141
                    689999********************************8765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (342 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       264  (0.0147247); expected 358.6 (0.02)
Passed bias filter:                      251  (0.0139997); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.47
# Mc/sec: 2209.38
//
Query:       EEA22971.1  [L=258]
Description: hypothetical protein PMAA_095740 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (258 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       491  (0.0273858); expected 358.6 (0.02)
Passed bias filter:                      369  (0.0205812); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.47u 0.30s 00:00:00.77 Elapsed: 00:00:00.52
# Mc/sec: 1504.18
//
Query:       EEA22972.1  [L=588]
Description: transcription factor sp3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (588 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       666  (0.0371465); expected 358.6 (0.02)
Passed bias filter:                      331  (0.0184617); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.77u 0.36s 00:00:01.12 Elapsed: 00:00:00.58
# Mc/sec: 3051.65
//
Query:       EEA22973.1  [L=194]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.2e-15   54.6   7.7    9.7e-15   54.3   7.7    1.1  1  MFS_1     Major Facilitator Superfamily
      4e-06   26.0   2.1    4.9e-06   25.7   2.1    1.1  1  Sugar_tr  Sugar (and other) transporter


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   54.3   7.7   1.1e-18   9.7e-15       1     117 [.      29     143 ..      29     161 .. 0.87

  Alignments for each domain:
  == domain 1  score: 54.3 bits;  conditional E-value: 1.1e-18
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfasslwlllvlrvlqGlga 99 
                 l+la+fl+al+r+i+++a+p  ++++++ s s ig+ ++ y+ ++++++l++G l      ++ +l ++ lf +g++++  a+++ +++++r ++G+g+
  EEA22973.1  29 LYLAIFLVALDRTIIATAIP-QITDEFN-SLSDIGWYASSYMMTSCAFQLFYGKLYVFDPTKWGFLSAIMLFEIGSAICGAAPNSVAFIWGRSIAGFGC 125
                 5799****************.8******.**************************8877788888888888888856666357877************* PP

       MFS_1 100 galfpagaaliadwfpke 117
                 +++f++++++++   p +
  EEA22973.1 126 SGIFSGAIVVMVPHNPAR 143
                 *******99987666665 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.7   2.1   5.5e-10   4.9e-06      44     120 ..      56     130 ..       3     140 .. 0.82

  Alignments for each domain:
  == domain 1  score: 25.7 bits;  conditional E-value: 5.5e-10
                 ...HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHH.HHHH CS
    Sugar_tr  44 ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigv.Glas 120
                 s +++g+ +s+++  + + +lf g+l  +   k+++l a++lf ig+++++aa+   +  ++i gR ++G+g+ G++s
  EEA22973.1  56 SLSDIGWYASSYMMTSCAFQLFYGKLYVFDPTKWGFLSAIMLFEIGSAICGAAP---NSVAFIWGRSIAGFGCsGIFS 130
                 66889*************************************************...8899***********944444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (194 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       404  (0.0225333); expected 358.6 (0.02)
Passed bias filter:                      283  (0.0157845); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.35s 00:00:00.97 Elapsed: 00:00:00.58
# Mc/sec: 1014.48
//
Query:       EEA22974.1  [L=135]
Description: hypothetical protein PMAA_095770 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
  ------ inclusion threshold ------
       0.11   13.1   0.2       0.15   12.6   0.2    1.2  1  Hemerythrin  Hemerythrin HHE cation binding domain


Domain annotation for each model (and alignments):
>> Hemerythrin  Hemerythrin HHE cation binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.2   8.6e-06      0.15       8      55 ..       6      55 ..       2      62 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 8.6e-06
                 HHHHHHHHHHHHHHHHHHH.HHHHCCC.HCCHHHHHHHHHHHHHHHHHHH CS
  Hemerythrin  8 eeHralrallerlralada.aaevhga.lrklaelldelvdeleaHhaaE 55
                 e+Hra+   ++++ +++d+ a++ +    ++l  lld ++ +l++H+++E
   EEA22974.1  6 EQHRAFIVGFRAVKSYLDSvAETPRRFsGAELISLLDDFAPQLHHHLTDE 55
                 7999999999999999999555444449999***********99999988 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (135 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       211  (0.0117686); expected 358.6 (0.02)
Passed bias filter:                      206  (0.0114898); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.57u 0.33s 00:00:00.89 Elapsed: 00:00:00.55
# Mc/sec: 744.95
//
Query:       EEA22975.1  [L=156]
Description: hypothetical protein PMAA_095780 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    5.3e-07   29.9   1.3    7.6e-07   29.4   1.3    1.2  1  PP-binding  Phosphopantetheine attachment site


Domain annotation for each model (and alignments):
>> PP-binding  Phosphopantetheine attachment site
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.4   1.3   4.2e-11   7.6e-07       5      66 ..      54     117 ..      51     118 .. 0.80

  Alignments for each domain:
  == domain 1  score: 29.4 bits;  conditional E-value: 4.2e-11
  PP-binding   5 elvaevlgvpleeidpdtdlf.dlGlDSllavellaaleeefgveipls..dlfehptlaelaay 66 
                 ++v+e +gv+l++++ d+ lf d G+DSll++ + ++++ee++++++l+   + ++p +++l ++
  EEA22975.1  54 QIVSEETGVALDDLA-DDCLFaDIGVDSLLSMVIPSRFREELNLDLDLEfsIFIDLPAVKNLKDF 117
                 89***********86.555555********************88665553166788888887765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (156 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       409  (0.0228122); expected 358.6 (0.02)
Passed bias filter:                      329  (0.0183502); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.32s 00:00:00.88 Elapsed: 00:00:00.53
# Mc/sec: 883.33
//
Query:       EEA22976.1  [L=395]
Description: aspergillopepsin F precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.6e-40  139.5   0.0    1.8e-40  139.3   0.0    1.0  1  Asp       Eukaryotic aspartyl protease


Domain annotation for each model (and alignments):
>> Asp  Eukaryotic aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  139.3   0.0     1e-44   1.8e-40       2     312 ..      83     388 ..      82     391 .. 0.86

  Alignments for each domain:
  == domain 1  score: 139.3 bits;  conditional E-value: 1e-44
                 EEEEEEETTTTEEEEEEEETT--SEEEEBTTESTSHCHHTSS-B-GGG-TT-EEEEEEEEEECTTS.EEEEEEEEEEEEETTEEEEEEEEEEEEEESSH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp   2 YfgeisiGtpeqkftvifDTGSsdlWVpsskckkssackshstydpskSstykkngkslsisYGdg.svsGflsqdtvkvggltvknqefgeatkepgs 99 
                 Y +++++G     + + +DT S+dlWV  + +         ++yd  +S+      ++++i+Y+dg  + G +++d vk+g++t  +q ++     ++s
  EEA22976.1  83 YRSPVKVGND--ILLLALDTSSADLWVKTKFSP----RAGTHVYD--QSTGTLLPYHHWQIRYSDGgIAGGDVYKDIVKIGDITSYEQGVETLLYLHTS 173
                 6667777766..68899**********877766....34555666..56666678999********89999*******************998887766 PP

                 HHTTSS.SSEEEE-S-GGGSCGGSCCH...HHHHHHTTSSSSSEEEEEE-STTSSEEEEEESSEEGGGEEEEEEEEEESS.TSSTEEEEEEEEETTEEE CS
                 xxxxxx.xxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxx RF
         Asp 100 tflaak.fdGiLGlgfkeisveeatpv...fdnlvsqglikepvfsvylnreeeeggeivfGgvDeskykGsltyvpvts.kgywqielesvtvggktv 193
                   l ++  dG++Gl+f++++++  tp    ++n+ + + + +pvf+  l   +++ g+  fG +D++k +G + y  v+  +gyw+i+ +++ +gg ++
  EEA22976.1 174 HSLLTDgLDGVVGLAFPSLNTVLPTPQgtfYENV-KLN-LLTPVFAASLK--HHAPGSFDFGFIDHTKHTGGILYKHVDPtRGYWNISCDGYAIGGGAI 268
                 55554449**************966666636665.444.558*******5..9*************************9889***************** PP

                 EEEEEEEEEEETTCSSEEEEHHHHHHHHHHHT.TEEEETTCEEEEETTGGGGSEEEEEEETTEEEEEEGGGGEEEESSSTTSEEEESEEECCTSSSEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp 194 lcssgcqailDtGTsllalptsivekiakaig.akksesegeyvvdCdslsslpdisftiggakitvpvselvlkeeeseesqCilglvseeegdlwiL 291
                 + ++ + a++Dt  sl+ l++siv+ +  +i  a +s ++g +++dC++    p++s+ +g+ kit+p   l + e  ++   C+ gl+++++ d+ iL
  EEA22976.1 269 TFDEPFYAVIDTTGSLVLLKESIVNMYYGNIRsAFYSLEHGGWIFDCHD--LIPSFSVRLGNYKITIPGPYLKYTEIPGT-PLCYGGLQKSPHDDYGIL 364
                 **************************99888615677788********8..89*******************99999866.8***************** PP

                 EHHHHTTEEEEEETTT...TEEEE CS
                 xxxxxxxxxxxxxxxx...xxxxx RF
         Asp 292 GdvFlrsayvvfdldn...nrvgl 312
                 G + l+  yv+fd +     rvg+
  EEA22976.1 365 GVMLLKTQYVIFDARRgrpPRVGF 388
                 *************86512245666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (395 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       284  (0.0158403); expected 358.6 (0.02)
Passed bias filter:                      272  (0.015171); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.65u 0.31s 00:00:00.96 Elapsed: 00:00:00.53
# Mc/sec: 2246.03
//
Query:       EEA22977.1  [L=799]
Description: HET domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (799 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       332  (0.0185175); expected 358.6 (0.02)
Passed bias filter:                      309  (0.0172346); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.65u 0.31s 00:00:00.96 Elapsed: 00:00:00.49
# Mc/sec: 4896.48
//
Query:       EEA22978.1  [L=251]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    9.4e-09   35.2   0.1    1.7e-08   34.3   0.1    1.4  1  DDE_1     DDE superfamily endonuclease


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.3   0.1   9.4e-13   1.7e-08       2      72 ..     107     177 ..     106     188 .. 0.88

  Alignments for each domain:
  == domain 1  score: 34.3 bits;  conditional E-value: 9.4e-13
       DDE_1   2 erltvllcanaagsekLkplvigkak.sprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrle.a 72 
                 ++++++++a  +++  +++++i+kak + r  ++   ++ ++d+++++++++w+t++i+ eWL  +f+++++ +
  EEA22978.1 107 REWVTAIEATNSTGWAIPSYIIFKAKkNVRLGWF---DNLPSDWRINISEHGWTTDQIGLEWLkTHFIPSINgR 177
                 7899********************9725677888...99999*********************99****99843 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (251 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       390  (0.0217525); expected 358.6 (0.02)
Passed bias filter:                      373  (0.0208043); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.28s 00:00:00.75 Elapsed: 00:00:00.46
# Mc/sec: 1655.91
//
Query:       EEA22979.1  [L=555]
Description: pogo transposable element, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.2e-33  116.2   0.0    2.2e-33  115.4   0.0    1.4  1  DDE_1        DDE superfamily endonuclease
    3.1e-11   43.2   1.1    9.8e-11   41.5   0.0    2.3  2  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
    2.9e-07   30.1   0.0    7.8e-07   28.7   0.0    1.7  1  HTH_psq      helix-turn-helix, Psq domain
  ------ inclusion threshold ------
      0.094   12.6   2.0       0.17   11.7   2.0    1.5  1  zf-CCHC_2    Zinc knuckle
       0.42   10.8   2.0        1.5    9.1   0.0    2.6  3  ORF6N        ORF6N domain
       0.44   10.7   2.5       0.78    9.9   2.5    1.4  1  zf-CCHC      Zinc knuckle


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  115.4   0.0   7.2e-37   2.2e-33       2     175 .]     204     373 ..     203     373 .. 0.96

  Alignments for each domain:
  == domain 1  score: 115.4 bits;  conditional E-value: 7.2e-37
       DDE_1   2 erltvllcanaagsekLkplvigkak.sprafkngektkkkldveyksnrkawltssifeeWL.kvfdkrle..aekrkilLlldssrshetvel.les 95 
                 ++++++++a  +++  L++++i+kak + r  ++   ++ + d+++++++++w+t++i+ eWL  +f++ +     +++ +L+ld+++sh t+e+   +
  EEA22979.1 204 REWVTAIEATNSTGWALPSYIIFKAKkNVRVGWF---DDLPDDWRINISDNGWTTDQIGLEWLkTHFIPYISgrTRGKYRMLILDGHGSHLTAEFdRTC 299
                 7899********************9726788899...99999*****************************99999*******************9*** PP

       DDE_1  96 elqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsketiksaf 175
                  ++ni  +++P++s +llqPld+g+++ lK++Y +q+ q + ++ n+++k       ld+l    kA++ a + +ti+++f
  EEA22979.1 300 TENNIIPICMPPHSLHLLQPLDVGCFAVLKRHYGQQVEQRMRDGFNHIDK-------LDFLMAFPKARTeAYKARTIQNSF 373
                 **************************************************.......9**********9999999999987 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.5   0.0   3.3e-14   9.8e-11       2      61 ..      70     125 ..      69     137 .. 0.90
   2 ?   -1.2   0.3       0.7   2.1e+03      14      35 ..     483     504 ..     481     519 .. 0.78

  Alignments for each domain:
  == domain 1  score: 41.5 bits;  conditional E-value: 3.3e-14
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT.S CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh.g 61 
                  + +E++L++W+ +l++rg p++++l+re+A+ l+      +++d +++ +W+++  kR  +
   EEA22979.1  70 QSEEESLVKWVLDLDRRGLPPRHSLVREMANYLL-----SQHGDQRVGDKWVYNLVKRRpE 125
                  578******************************6.....3469***************854 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.7
                  HHC-CT---SCHHHHHHHHHHH CS
  HTH_Tnp_Tc5  14 qlrergipitgelirekAqela 35 
                  q  ++ i+i + + re+Aq+l 
   EEA22979.1 483 QKSKKQISIEQGITREEAQALV 504
                  44788999999999*****995 PP

>> HTH_psq  helix-turn-helix, Psq domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.7   0.0   2.6e-10   7.8e-07       2      39 ..      16      54 ..      15      59 .. 0.91

  Alignments for each domain:
  == domain 1  score: 28.7 bits;  conditional E-value: 2.6e-10
     HTH_psq  2 pealaaAleavvnGk.mSirkAArkYgiPrsTLwrrkrg 39
                + ++ +A+ + +n+  + +++AA++Y+iPr+TL+rr+rg
  EEA22979.1 16 EGRILLAISDLQNERiLRVAQAASVYNIPRTTLQRRLRG 54
                56788999999****9*********************98 PP

>> zf-CCHC_2  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   2.0   5.6e-05      0.17       5      21 .]     535     551 ..     531     551 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 5.6e-05
   zf-CCHC_2   5 vChiCgkkGHyIqdCPt 21 
                  C  Cg+ GH I+ CP+
  EEA22979.1 535 RCSGCGVEGHRINRCPN 551
                 6888************6 PP

>> ORF6N  ORF6N domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.1   0.0    0.0005       1.5       3      53 ..      23      74 ..      21     110 .. 0.83
   2 ?   -2.1   0.0       1.6   4.7e+03      50      80 ..     149     178 ..     121     180 .. 0.69
   3 ?   -0.5   0.7       0.5   1.5e+03      17      79 ..     432     496 ..     416     499 .. 0.62

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0005
       ORF6N  3 iyeirgqrVmldkdlAelYevetkrlnqavkrnkeRFped.fmfqLtkeele 53
                i  ++++r++  ++ A++Y+++  +l+++ +  ++R + +    +Lt+ e e
  EEA22979.1 23 ISDLQNERILRVAQAASVYNIPRTTLQRRLRGVQQRSEVRaNSHKLTQSEEE 74
                667899***************************9999988888889887766 PP

  == domain 2  score: -2.1 bits;  conditional E-value: 1.6
       ORF6N  50 eelersqiatlkrgskskylpylfTEqGvlm 80 
                 e ++r q a++ +++   + ++ f E+G +m
  EEA22979.1 149 EHFDRVQAAIS-EYGILPEDIFNFDETGFAM 178
                 44556677774.4666777788888888887 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 0.5
       ORF6N  17 lAelYevetkrlnqavkrnkeRFped..fmfqLtkeelersqiatl.krgskskylpylfTEqGvl 79 
                 + e  + +++ +nqa+ r ++ ++    +   + ke+++  + a + ++ + +k++  +  EqG++
  EEA22979.1 432 ISERTGSPNQGINQAIIRMSKAYETTmhDLLLIRKENYD-LRAAHEkEKRKRQKSKKQISIEQGIT 496
                 555556667778888888888887666567777788888.55555543333344445555677765 PP

>> zf-CCHC  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   2.5   0.00026      0.78       3      18 .]     536     551 ..     534     551 .. 0.90

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00026
                 TSSSSSSSSTTTTSTS CS
     zf-CCHC   3 CynCGepGHiardCpk 18 
                 C  CG +GH+ + Cp+
  EEA22979.1 536 CSGCGVEGHRINRCPN 551
                 777************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (555 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       944  (0.0526521); expected 358.6 (0.02)
Passed bias filter:                      517  (0.028836); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.62u 0.32s 00:00:00.94 Elapsed: 00:00:00.46
# Mc/sec: 3627.94
//
Query:       EEA22980.1  [L=426]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.3e-19   70.5   0.0    2.7e-19   69.5   0.0    1.5  1  DDE_1        DDE superfamily endonuclease
    5.7e-10   39.1   0.0    1.2e-09   38.1   0.0    1.5  1  HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
    1.8e-06   27.6   0.0    3.8e-06   26.5   0.0    1.6  1  HTH_psq      helix-turn-helix, Psq domain
     0.0075   16.5   2.0        0.9    9.8   1.0    2.5  2  Herpes_UL14  Herpesvirus UL14-like protein
  ------ inclusion threshold ------
       0.06   13.1   0.0       0.35   10.6   0.0    2.2  2  DDE_3        DDE superfamily endonuclease
      0.066   13.3   0.1       0.51   10.5   0.0    2.5  3  HTH_28       Helix-turn-helix domain


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.5   0.0   8.9e-23   2.7e-19      72     175 .]     227     325 ..     205     325 .. 0.94

  Alignments for each domain:
  == domain 1  score: 69.5 bits;  conditional E-value: 8.9e-23
       DDE_1  72 aekrkilLlldssrshetvel.leselqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwn.avsk 168
                 +++++ +L+ld+++sh t+e+   + ++ni  +++P++s++llqPld+g+++ lK++Y +q+ q + ++ n+++k       ld+l    kA++ a + 
  EEA22980.1 227 SIGSYRMLILDGHGSHLTAEFdRTCTENNIIPICMPPHSSHLLQPLDVGCFAVLKRHYGQQVEQRMRDGFNHIDK-------LDFLMAFPKARTeAYKA 318
                 67899****************9*****************************************************.......9**********999999 PP

       DDE_1 169 etiksaf 175
                 +ti+++f
  EEA22980.1 319 RTIQNSF 325
                 9999987 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.1   0.0   3.9e-13   1.2e-09       2      61 ..      70     125 ..      69     130 .. 0.90

  Alignments for each domain:
  == domain 1  score: 38.1 bits;  conditional E-value: 3.9e-13
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT.S CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh.g 61 
                  + +E++L++W+ +l++rg p++++l+re+ + l+     l++++++++k+W+ + +kR  +
   EEA22980.1  70 QSEEDSLVKWVLDLDRRGLPPRHSLVREMVNYLL-----LQHGKPQVGKNWVTNLIKRRpE 125
                  578*****************************95.....6679***************854 PP

>> HTH_psq  helix-turn-helix, Psq domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.5   0.0   1.3e-09   3.8e-06       2      41 ..      16      56 ..      15      59 .. 0.93

  Alignments for each domain:
  == domain 1  score: 26.5 bits;  conditional E-value: 1.3e-09
     HTH_psq  2 pealaaAleavvnGk.mSirkAArkYgiPrsTLwrrkrgky 41
                + ++++A+ +  nG  + ir+A r+Y+iPr+TL+ r++g++
  EEA22980.1 16 EGKIQLAISDLKNGRiLNIREATRIYDIPRTTLRDRLKGIE 56
                678999********************************986 PP

>> Herpes_UL14  Herpesvirus UL14-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.0   0.0    0.0092        28     122     145 ..      59      82 ..      39      83 .. 0.84
   2 !    9.8   1.0    0.0003       0.9      12      86 ..     310     385 ..     304     387 .. 0.78

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0092
  Herpes_UL14 122 ndeleadeeldegdeaLLvkWqLe 145
                  +++  ++++l + +e+ LvkW+L+
   EEA22980.1  59 GEKRANHHKLTQSEEDSLVKWVLD 82 
                  77889****************996 PP

  == domain 2  score: 9.8 bits;  conditional E-value: 0.0003
  Herpes_UL14  12 hlraevykertLe..llseGvstqdPaFveaFtaAkeaeedlkaqlrsdaRlesvrrkik..riqakveeqaelrsiLk 86 
                  + r e+yk+rt++  ++  G  + +P  ++   aA+e+e++ +   +s++ + s+++ i+  ++qa v++q e  + ++
   EEA22980.1 310 KARTEAYKARTIQnsFVATGLVPFNPDRMHDLRAANEKEKQKRQ--KSKKQI-SIEQGITreEVQALVQGQIEASQAVT 385
                  6799********866899**************999988766544..555554.56666652269*******99887765 PP

>> DDE_3  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.5   0.0      0.31   9.1e+02       2      48 ..     168     217 ..     167     228 .. 0.74
   2 ?   10.6   0.0   0.00012      0.35      81     119 ..     232     268 ..     204     286 .. 0.89

  Alignments for each domain:
  == domain 1  score: -0.5 bits;  conditional E-value: 0.31
       DDE_3   2 vvfiDEsgfqlgt.vrrrawakkGkr..erleeygrrgrvnligaldekg 48 
                 ++ +DE+gf  g    ++     ++   ++l + g+r+ v++i a++  g
  EEA22980.1 168 IYNFDETGFAMGLcATAKVITGSDRYarPKLLQPGNREWVTAIEATNSTG 217
                 66789999999987777777777776434489999999999999988776 PP

  == domain 2  score: 10.6 bits;  conditional E-value: 0.00012
       DDE_3  81 ivlilDnasiHkseslrelveeeadrlellylPpySPel 119
                  +lilD+++ H  +++ +   e   ++  + +Pp+S++l
  EEA22980.1 232 RMLILDGHGSHLTAEFDRTCTE--NNIIPICMPPHSSHL 268
                 79********************..*************98 PP

>> HTH_28  Helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00017      0.51       5      34 ..      22      53 ..      20      60 .. 0.91
   2 ?   -3.6   0.0       4.3   1.3e+04      14      24 ..     153     163 ..     147     169 .. 0.69
   3 ?   -1.4   0.0      0.87   2.6e+03      11      33 ..     352     374 ..     342     376 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00017
      HTH_28  5 iikllaaGh..svreaArelgisrrtvyrWik 34
                +i  l++G+  ++rea r++ i r+t+++ +k
  EEA22980.1 22 AISDLKNGRilNIREATRIYDIPRTTLRDRLK 53
                6788999*99******************9998 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 4.3
      HTH_28  14 svreaArelgi 24 
                 +vr+a  e+gi
  EEA22980.1 153 RVRDAISEYGI 163
                 77888888887 PP

  == domain 3  score: -1.4 bits;  conditional E-value: 0.87
      HTH_28  11 aGhsvreaArelgisrrtvyrWi 33 
                 +++s ++++ e gi+r+ v+ ++
  EEA22980.1 352 RQKSKKQISIEQGITREEVQALV 374
                 45688899999999999887766 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (426 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1132  (0.0631379); expected 358.6 (0.02)
Passed bias filter:                      796  (0.0443973); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.75u 0.39s 00:00:01.14 Elapsed: 00:00:00.57
# Mc/sec: 2267.00
//
Query:       EEA22981.1  [L=465]
Description: hypothetical protein PMAA_095840 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.6e-18   66.3   0.0    4.1e-18   65.7   0.0    1.2  1  RVT_1     Reverse transcriptase (RNA-dependent DNA polymerase
    2.3e-05   25.0   0.0      8e-05   23.3   0.0    1.8  2  zf-RVT    zinc-binding in reverse transcriptase


Domain annotation for each model (and alignments):
>> RVT_1  Reverse transcriptase (RNA-dependent DNA polymerase)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.7   0.0   4.6e-22   4.1e-18       3     145 ..      99     252 ..      97     264 .. 0.89

  Alignments for each domain:
  == domain 1  score: 65.7 bits;  conditional E-value: 4.6e-22
                 -TT.......S-EEE......-THHHHCTB--...........-------HHHH.................HCCHTS--EEEEEEBCCGCCCSBB-GGG CS
       RVT_1   3 Kkg......pgsyRpisllsvdykalnkliakrLkdvl..ekllsenqpgfrpgrstldav....edllkalkkkkkaklllklDlkkaFdsvpleell 89 
                 K+g      ++ yR+isll++++k+++k +a  ++d++  + l+ e q+g r++rs + av        + ++ ++k   +l++D+k+aFd v   e+ 
  EEA22981.1  99 KPGkgiymvAKAYRVISLLKCLGKVVEKPVAGLITDYAeaQGLFYEGQFGARRQRSAVAAVvcliG-EIENAWGNGKLGACLFMDIKGAFDYVVSIEQA 196
                 666677888899**************************9999*******************99954.44445899999*************98777776 PP

                 GGGG-EEET.........................TEEEEESB--ST-TTHHHHHHH CS
       RVT_1  90 rkltafkvptklinliksflstrsfsvrvngeeskgryekkglpqGsvlSPllfnl 145
                 ++      +  l++++ sf+ +r++ + ++g+ s++ +++ glpqGs++SP+ f l
  EEA22981.1 197 YRGSPGHGDGDLVRWVASFMLNRRAMLVIDGHISEEVPISSGLPQGSPVSPIPFVL 252
                 66666677789*********************88******************9976 PP

>> zf-RVT  zinc-binding in reverse transcriptase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0      0.99   8.9e+03      41      59 ..      33      51 ..      31      55 .. 0.83
   2 !   23.3   0.0   8.9e-09     8e-05      26      79 ..     330     383 ..     323     386 .. 0.94

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.99
      zf-RVT 41 knrlptadnllkrgiesss 59
                 n++ ++d l+++gie+ +
  EEA22981.1 33 ANKIAVRDALFSQGIEKAP 51
                58999*******9999765 PP

  == domain 2  score: 23.3 bits;  conditional E-value: 8.9e-09
      zf-RVT  26 skappkvkfflWlllknrlptadnllkrgiesssrCqlCgqeeEtieHlfleCp 79 
                 +kap +v    + l +++ p+   l++ ++  s +C  Cg+  Eti+H+++eC+
  EEA22981.1 330 AKAPKRVASCYYQLKTGHAPIGTYLHRIKARDSLECRACGELRETISHIIFECR 383
                 68999999999******************************************6 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (465 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       290  (0.0161749); expected 358.6 (0.02)
Passed bias filter:                      259  (0.0144459); expected 358.6 (0.02)
Passed Vit filter:                        21  (0.00117129); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.66u 0.34s 00:00:01.00 Elapsed: 00:00:00.56
# Mc/sec: 2489.02
//
Query:       EEA22982.1  [L=383]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (383 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       361  (0.020135); expected 358.6 (0.02)
Passed bias filter:                      343  (0.019131); expected 358.6 (0.02)
Passed Vit filter:                        22  (0.00122706); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.67u 0.33s 00:00:01.00 Elapsed: 00:00:00.56
# Mc/sec: 2042.82
//
Query:       EEA22983.1  [L=616]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (616 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       498  (0.0277762); expected 358.6 (0.02)
Passed bias filter:                      432  (0.024095); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.76u 0.32s 00:00:01.08 Elapsed: 00:00:00.54
# Mc/sec: 3458.22
//
Query:       EEA22984.1  [L=147]
Description: hypothetical protein PMAA_095870 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (147 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       511  (0.0285013); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.60u 0.31s 00:00:00.90 Elapsed: 00:00:00.54
# Mc/sec: 826.16
//
Query:       EEA22985.1  [L=560]
Description: splicing factor 3b, subunit 2, 145kD [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.4e-59  198.2   0.9      1e-58  197.0   0.9    1.7  1  DUF382    Domain of unknown function (DUF382)
    1.9e-20   72.4   3.8    3.8e-20   71.5   3.8    1.5  1  PSP       PSP


Domain annotation for each model (and alignments):
>> DUF382  Domain of unknown function (DUF382)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  197.0   0.9   1.1e-62     1e-58       1     127 []     134     260 ..     134     260 .. 0.99

  Alignments for each domain:
  == domain 1  score: 197.0 bits;  conditional E-value: 1.1e-62
      DUF382   1 kkPevvevaDvdakdPvllvklKssknvvpvpshWsskreylsgkrglekkpfelPkfikeTgieelrealeekeeekslkekarekvqpklgkldidy 99 
                 +kP++ve++D++a+dP+llv++K+++nvvpvp+hWs kreyls+krg+ek+ f lPkfi+eTgi+e+r+a+ ek+e+ +lk+k+re+vqpk+g+ldidy
  EEA22985.1 134 QKPDLVEWTDTSAPDPRLLVHIKAHRNVVPVPTHWSLKREYLSSKRGIEKPAFALPKFIQETGISEMRDAALEKQEQATLKQKQRERVQPKMGRLDIDY 232
                 58************************************************************************************************* PP

      DUF382 100 kkLhdaFfklqtkPkllkfGdlyyegke 127
                 +kL++aFf++qtkP+l+++G++yyegke
  EEA22985.1 233 QKLYEAFFRFQTKPELTRYGEVYYEGKE 260
                 **************************97 PP

>> PSP  PSP
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.5   3.8   4.2e-24   3.8e-20       1      46 []     269     314 ..     269     314 .. 0.98

  Alignments for each domain:
  == domain 1  score: 71.5 bits;  conditional E-value: 4.2e-24
         PSP   1 kPGviSaeLReALglqegqlPpWiykMqrlGlPPgYpklkipGlna 46 
                 +PG++S+eL+eAL++++g++PpW+++ qr+G+PP+Yp lkipGlna
  EEA22985.1 269 RPGELSDELKEALNIPPGAPPPWLINQQRFGPPPSYPALKIPGLNA 314
                 8*******************************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (560 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1401  (0.0781416); expected 358.6 (0.02)
Passed bias filter:                      496  (0.0276647); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.69u 0.34s 00:00:01.03 Elapsed: 00:00:00.50
# Mc/sec: 3367.43
//
Query:       EEA22986.1  [L=530]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (530 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       714  (0.0398237); expected 358.6 (0.02)
Passed bias filter:                      285  (0.015896); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.60u 0.25s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 3563.67
//
Query:       EEA22987.1  [L=213]
Description: er lumen protein retaining receptor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.7e-56  190.5   9.1    4.8e-56  189.7   9.1    1.4  1  ER_lumen_recept  ER lumen protein retaining receptor
    0.00022   21.0  12.3       0.34   10.7   0.1    4.4  5  PQ-loop          PQ loop repeat


Domain annotation for each model (and alignments):
>> ER_lumen_recept  ER lumen protein retaining receptor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  189.7   9.1   5.4e-60   4.8e-56       1     147 []      28     170 ..      28     170 .. 0.98

  Alignments for each domain:
  == domain 1  score: 189.7 bits;  conditional E-value: 5.4e-60
  ER_lumen_recept   1 svaGlSlktqilyalvfltryldlflylreeislyntlmkialillsiyiiylilvkfketyekekDtfklellivpslllallfhpgssktll 94 
                      s++GlS+k+q+ly++vf+tryldlf++++   slynt++ki++i +s+y+iyl+l  +k t++ + Dtfk+e+l+  s+lla+lf +  ++t+ 
       EEA22987.1  28 SCSGLSFKSQVLYLIVFVTRYLDLFWTFT--DSLYNTVFKILFIGSSFYTIYLMLNDYKPTQDPNTDTFKVEYLLGFSALLAILFPQ--HYTIS 117
                      8***********************97776..69*************************************************99987..***** PP

  ER_lumen_recept  95 evlwtfsiiLesvAilPQlillqktgevesltshyvfalglyRalyllnWivr 147
                      e+lwtfsi+LesvAilPQl++lq+tge++++t+hy+falglyRaly++nWi+r
       EEA22987.1 118 EILWTFSIWLESVAILPQLFMLQRTGEADTITTHYLFALGLYRALYIPNWIYR 170
                      ***************************************************97 PP

>> PQ-loop  PQ loop repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0      0.45   4.1e+03      42      55 ..       6      19 ..       3      25 .. 0.73
   2 !    7.7   1.1   0.00032       2.9      27      57 ..      26      56 ..      20      60 .. 0.87
   3 !    8.0   0.1   0.00028       2.5      40      60 ..      66      86 ..      62      87 .. 0.86
   4 ?   -0.9   0.0      0.16   1.4e+03      12      24 ..     104     116 ..      99     117 .. 0.71
   5 !   10.7   0.1   3.8e-05      0.34       1      39 [.     116     154 ..     116     173 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.45
     PQ-loop 42 llGdilsllyliln 55
                ll+d+  l+++++ 
  EEA22987.1  6 LLADFSHLISILIL 19
                77888888888765 PP

  == domain 2  score: 7.7 bits;  conditional E-value: 0.00032
     PQ-loop 27 rkSteGlSilflllwllGdilsllylilngf 57
                + S++GlS+ + +l l+ ++++ l l+++  
  EEA22987.1 26 TSSCSGLSFKSQVLYLIVFVTRYLDLFWTFT 56
                569******************9999888765 PP

  == domain 3  score: 8.0 bits;  conditional E-value: 0.00028
     PQ-loop 40 lwllGdilsllylilngfpps 60
                + ++G++++++yl+ln++ p 
  EEA22987.1 66 ILFIGSSFYTIYLMLNDYKPT 86
                679*************99875 PP

  == domain 4  score: -0.9 bits;  conditional E-value: 0.16
     PQ-loop  12 lwlvsyiPQiikN 24 
                   l+ ++PQ +++
  EEA22987.1 104 ALLAILFPQHYTI 116
                 5566789999986 PP

  == domain 5  score: 10.7 bits;  conditional E-value: 3.8e-05
     PQ-loop   1 lseilgyislvlwlvsyiPQiikNykrkSteGlSilfll 39 
                 +seil ++s+ l++v+ +PQ+ +  ++  ++ + + +l+
  EEA22987.1 116 ISEILWTFSIWLESVAILPQLFMLQRTGEADTITTHYLF 154
                 799***********************9999988887777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (213 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       414  (0.0230911); expected 358.6 (0.02)
Passed bias filter:                      162  (0.00903564); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.42u 0.29s 00:00:00.71 Elapsed: 00:00:00.43
# Mc/sec: 1477.74
//
Query:       EEA22988.1  [L=397]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    9.4e-08   32.1   0.8    9.4e-08   32.1   0.8    2.0  3  Integrase_H2C2  Integrase zinc binding domain


Domain annotation for each model (and alignments):
>> Integrase_H2C2  Integrase zinc binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -5.6   2.0         1   1.8e+04      10      16 ..      85      91 ..      77      99 .. 0.55
   2 ?   -3.3   0.2      0.58     1e+04      32      39 ..     196     203 ..     193     204 .. 0.79
   3 !   32.1   0.8   5.2e-12   9.4e-08       8      56 ..     234     281 ..     229     282 .. 0.94

  Alignments for each domain:
  == domain 1  score: -5.6 bits;  conditional E-value: 1
  Integrase_H2C2 10 lkeaHds 16
                    l+++H +
      EEA22988.1 85 LSQHHHH 91
                    4444444 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 0.58
  Integrase_H2C2  32 ryyWpgmr 39 
                     r++ ++m 
      EEA22988.1 196 RFWVKKMF 203
                     89999996 PP

  == domain 3  score: 32.1 bits;  conditional E-value: 5.2e-12
  Integrase_H2C2   8 eilkeaHdsagHlGiektlerlrrryyWpgmrkdvkkyvksCetCqrrk 56 
                     +il++aH++  H G++kt +++r+ y W   ++ + ++vk C+tCq r+
      EEA22988.1 234 KILTRAHQQCQHGGRDKTSAQVRQIYSWVP-KELISRFVKICPTCQVRR 281
                     89**************************98.9**************875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (397 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       621  (0.0346366); expected 358.6 (0.02)
Passed bias filter:                      474  (0.0264376); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.26s 00:00:00.78 Elapsed: 00:00:00.43
# Mc/sec: 2800.34
//
Query:       EEA22989.1  [L=985]
Description: cytokinesis regulator (Byr4), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (985 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       489  (0.0272742); expected 358.6 (0.02)
Passed bias filter:                      285  (0.015896); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.63u 0.26s 00:00:00.89 Elapsed: 00:00:00.40
# Mc/sec: 7440.58
//
Query:       EEA22990.1  [L=391]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.3e-06   27.6  17.9    2.1e-06   26.8  17.9    1.5  1  XRCC4         DNA double-strand break repair and V(D)J recomb
  ------ inclusion threshold ------
       0.12   11.0  23.4       0.19   10.3  23.4    1.3  1  TFIIF_alpha   Transcription initiation factor IIF, alpha subu
       0.67   10.0  13.5        1.3    9.0   4.0    2.1  2  Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C
        1.8    9.0   6.6        1.3    9.5   0.3    3.5  4  FlaC_arch     Flagella accessory protein C (FlaC)


Domain annotation for each model (and alignments):
>> XRCC4  DNA double-strand break repair and V(D)J recombination protein XRCC4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8  17.9   4.8e-10   2.1e-06     154     319 ..     167     319 ..      99     343 .. 0.68

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 4.8e-10
       XRCC4 154 erLlrdwsdvterlekyvkakEeleadLYkrFilvLNEKKaKiRsLqkllkelqeseesteqkrekaaksdkasdeeedydgstdeeseeeakkpsska 252
                 +   +  +d++  l+  v++k e e+ L   F  vLNEKK KiR+ q+ll  ++    ++e++re    s + ++eee++  s  +  +++a+  ++ +
  EEA22990.1 167 QAAEKSIKDLKTSLDDLVQSKREHENMLLGSFAQVLNEKKLKIRNQQRLLASAN---VDSEKARELE--STMDQEEEEEAPKSRRNKRKAPAR--QQDN 258
                 555667889999**********************************99995444...3334444433..334555666666777766665555..3334 PP

       XRCC4 253 easskddsllsseDitdvAPsRKrRqRlqkkleteakvatqeeekkekekldssakkaskkeslsae 319
                 e s++dd   ++ Di    PsR+        ++++a+ + +ee  +e e++++ ++ ++++es +ae
  EEA22990.1 259 EPSDSDDEF-EKMDIDKPTPSRRGVA----AAKAQAEEEEEEEGVEEDERPETPQPLEEETES-EAE 319
                 444455555.779***999*995544....444455555555555555666655555444443.222 PP

>> TFIIF_alpha  Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3  23.4   4.2e-05      0.19     182     335 ..     186     333 ..     157     344 .. 0.65

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 4.2e-05
                  HXXXXXX.....XXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....XXXXXXXXXXXXX.XXXXXXXX CS
  TFIIF_alpha 182 kkalkkgeaavgdedeeeekkkgggGrskdLkikdkegddeedsdesdkgdededeekkkkKkkkkaknkkkldddkkkkrgsdddadeydsddGdde 279
                   k+ +++    +  +  +ekk + + +++ L  + + ++++    es  ++e+e+e+ k +++k+ka  +++  d+  ++ +sdd+  + d+d+    
   EEA22990.1 186 SKREHENMLLGSFAQVLNEKKLKIRNQQR-LLASANVDSEKARELESTMDQEEEEEAPKSRRNKRKAPARQQ--DN--EPSDSDDEFEKMDIDKPTPS 278
                  45555443322222223332222233333.444444466666666677777888888887887888777666..55..599***************** PP

                  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
  TFIIF_alpha 280 grEldyisDdsasendpeeredkkseEeeekkeieqdedeeekeeekkeeegklsk 335
                   r +     + ++e+++e  e+ + +E++++ e+e  e+e e+e   ++ +++ +k
   EEA22990.1 279 RRGVAAAKAQAEEEEEEEGVEEDERPETPQPLEEET-ESEAEEERMASPPDEQPQK 333
                  *****9999999999999999999999999988665.5555555554444444444 PP

>> Baculo_PEP_C  Baculovirus polyhedron envelope protein, PEP, C terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   4.0    0.0003       1.3      22      99 ..      56     131 ..      53     141 .. 0.86
   2 ?    6.3   2.3    0.0021       9.4      29      85 ..     156     211 ..     136     220 .. 0.77

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.0003
  Baculo_PEP_C  22 LnairlqnvqilaqlatlldaietqLnalsedlksllaeldtrld.tlltnLtdalnalqdtlrneLtnlnsiltnLls 99 
                   L++ir++n q      + l++i +++  ++ d ++l +++d++++ t+l + +d +n+l  ++r++++++++ +++L+ 
    EEA22990.1  56 LKDIRAKNFQG---TDQELEQILKSVLRIQIDTSQLGPKQDSEIEaTALIKAKDEVNELVINVRKKIDSITQRVATLTL 131
                   78888888886...4678888888899999999*********99725678999***********************985 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0021
  Baculo_PEP_C  29 nvqilaqlatlldaietqLnalsedlksllaeldtrldtlltnLtdalnalqdtlrn 85 
                   + qi + l+t+l+a e+++++l+++l +l+++ +++ + ll    + ln+ + ++rn
    EEA22990.1 156 EHQI-STLTTQLQAAEKSIKDLKTSLDDLVQSKREHENMLLGSFAQVLNEKKLKIRN 211
                   5577.8899999999999999999999999988887666666666666655555555 PP

>> FlaC_arch  Flagella accessory protein C (FlaC)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.9   0.0         1   4.6e+03      20      33 ..      68      81 ..      54      84 .. 0.66
   2 ?    0.8   0.1      0.15   6.8e+02      25      39 ..     114     128 ..      96     143 .. 0.75
   3 ?    9.5   0.3   0.00029       1.3       2      35 ..     152     185 ..     151     191 .. 0.81
   4 ?   -2.8   0.0         2   8.8e+03      17      28 ..     363     374 ..     361     375 .. 0.86

  Alignments for each domain:
  == domain 1  score: -1.9 bits;  conditional E-value: 1
   FlaC_arch 20 kkeneelsksveel 33
                 +e+e++ ksv ++
  EEA22990.1 68 DQELEQILKSVLRI 81
                45666666666554 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.15
   FlaC_arch  25 elsksveelkenVkd 39 
                 +++k+++ + ++V  
  EEA22990.1 114 NVRKKIDSITQRVAT 128
                 467777777777754 PP

  == domain 3  score: 9.5 bits;  conditional E-value: 0.00029
   FlaC_arch   2 idelEnklsklsteletvkkeneelsksveelke 35 
                 +d  E ++s l t+l+ ++k++++l++s+++l +
  EEA22990.1 152 TDVYEHQISTLTTQLQAAEKSIKDLKTSLDDLVQ 185
                 5666888999999999999999999999998866 PP

  == domain 4  score: -2.8 bits;  conditional E-value: 2
   FlaC_arch  17 etvkkeneelsk 28 
                 +t+k+e e+++k
  EEA22990.1 363 DTAKRETEKVRK 374
                 7999***99987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (391 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      2227  (0.124212); expected 358.6 (0.02)
Passed bias filter:                      621  (0.0346366); expected 358.6 (0.02)
Passed Vit filter:                        84  (0.00468515); expected 17.9 (0.001)
Passed Fwd filter:                        22  (0.00122706); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.74u 0.34s 00:00:01.08 Elapsed: 00:00:00.50
# Mc/sec: 2364.77
//
Query:       EEA22991.1  [L=735]
Description: NADH-ubiquinone oxidoreductase, subunit G, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      5e-72  243.2   0.0    9.8e-70  235.7   0.0    2.2  1  Molybdopterin    Molybdopterin oxidoreductase
    4.4e-18   65.7   0.1    1.1e-17   64.5   0.1    1.7  1  NADH_dhqG_C      NADH-ubiquinone oxidoreductase subunit G, C-
    1.8e-17   62.6   0.2    1.8e-17   62.6   0.2    2.2  2  NADH-G_4Fe-4S_3  NADH-ubiquinone oxidoreductase-G iron-sulfur
    6.1e-16   58.2   0.3    2.4e-15   56.3   0.3    2.1  1  Fer2_4           2Fe-2S iron-sulfur cluster binding domain
    6.2e-05   22.9   2.7    6.6e-05   22.8   0.2    2.2  2  Fer2             2Fe-2S iron-sulfur cluster binding domain
  ------ inclusion threshold ------
      0.095   12.4   0.0        1.9    8.2   0.0    2.4  2  TPP_enzyme_M     Thiamine pyrophosphate enzyme, central domai
       0.11   12.4   1.1        3.4    7.6   0.3    2.6  2  Fer4             4Fe-4S binding domain
       0.21   11.7   2.2          4    7.6   2.2    2.6  1  Fer4_19          Divergent 4Fe-4S mono-cluster
        4.2    8.0   6.5       0.45   11.1   1.4    2.1  2  Fer4_17          4Fe-4S dicluster domain
        7.7    7.3   6.5        1.5    9.5   1.6    2.5  2  Fer4_4           4Fe-4S binding domain


Domain annotation for each model (and alignments):
>> Molybdopterin  Molybdopterin oxidoreductase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  235.7   0.0   5.4e-73   9.8e-70       1     431 [.     300     625 ..     300     626 .. 0.94

  Alignments for each domain:
  == domain 1  score: 235.7 bits;  conditional E-value: 5.4e-73
                    B--S-EEECTTTTTSEEEE--HHHHHHHHHHHHHHHHHHCSGGGEEE.EEBTSSCSHHHHHHHHHHHHHTT-EEE-BEECCGGGTTHHHHCHHCCC CS
  Molybdopterin   1 RlkyPmvRkqargeGkFvrvsWdeAleliaaslkytikkygpdrvag.fssgplmsmeslaslkkllsllggknlsfydwyadlppasaqqtigsd 95 
                    Rl++P++R   r eGkFv+++W++Al+++a+++ ++  k ++    + +++g+l+++esl+++k+l+++lg+ nl++  +++  p a+     g d
     EEA22991.1 300 RLTNPLIR---R-EGKFVPATWEQALTEVASAHARLNPKANE----FkAVAGQLVETESLVAMKDLANKLGSDNLALDMPNGGAPIAH-----GVD 382
                    9*******...9.**********************7777777....99*************************************998.....9** PP

                    CCTTTS-SS-CCGGGG-SEEEEESS-HHHHSHHHHHHHHHHHHTTC-EEEEECSSB-HCGGGCSEEEEEHTTTHHHHHHHHHHHHHHCCCCTCHHH CS
  Molybdopterin  96 srsnyessnpledlensdliilwGsNvreerpilnarirkaalkkkakvivigpryaellkfadewlaikpgtdaalalamghvilqelkvdkefl 191
                     rsny+++++++++e++d+i+l+G+N+r e+ +lnarirk++l+++++v+ +g+ ++  ++f  e+l+++  +++   l+++  + ++l  +k   
     EEA22991.1 383 VRSNYLFNSKIVGVEEADAILLVGTNPRYEAAVLNARIRKQYLRSDLQVGLVGESFE--STFGFEHLGADVSSLQSA-LSGE--FGKKLASAK--- 470
                    *********************************************************..99***********99998.6666..*********... PP

                    HHHEECHHHCCCCCCCEECCSHHHHHHCCHHHHHHHHHHHHHHTSSEEEEECHHHHTSTTHHHHHHHHHHHHHHCTHCSSTTCEEEEESSCTTHHH CS
  Molybdopterin 192 rkytygkeetdmpllvtleeetgkkkevvariarelarnaaktagksmiivGaglnhrqdgdaiyravinLallvgnvgqpgGgwahlnGqlilag 287
                                                                 ++miivG  + ++ d + ++++v +++       +   +w+++n   +l++
     EEA22991.1 471 ---------------------------------------------RPMIIVGSAIAEHPDAKSVFETVGQFVEKHATTFR-TDEWQGYN---VLQR 517
                    .............................................****************************9887777.55******...**** PP

                    CHHHHTCCTTCCCCCCCTTHHHHHCCCTTTCSTSS--ECGGCHHHHHHTTSSSEEEEESH.HHHHSTTSCCCHCHHHCSSEEEEEESCS.SHHHHT CS
  Molybdopterin 288 aaekvgalpvllsvkslkeekikfaaeqpgnlgnfprnlfversnllkssgkkvlyllgnnpevdhadenevekalekldlvvvldgrl.tstaly 382
                    aa+++ga+                      ++g++ +   v       ++ +k+++llg       ade +      ++d++vv++g++ +++a+ 
     EEA22991.1 518 AASRAGAY----------------------EVGFTAPSPEV------AKTTPKMVWLLG-------ADEINA--SEIPKDAFVVYQGHHgDRGAQL 576
                    ********......................66663333333......346789999***.......999888..5568****************** PP

                    SSEEEEBE-CCGSEEEEE-TTSEEEEEEESSS-STT-BEHHHHHHHHHH CS
  Molybdopterin 383 aDiiLPaatwyEkedlytndegrfqhlkqavsppgeaksdwkIlkaLak 431
                    aD++LP+a+++Ek+++y+n+egr+q +++a+s pg a++dwkI++a+++
     EEA22991.1 577 ADVVLPGAAYTEKSGTYVNTEGRVQVTRAATSLPGAARDDWKIIRAVSE 625
                    ***********************************************97 PP

>> NADH_dhqG_C  NADH-ubiquinone oxidoreductase subunit G, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   64.5   0.1   5.9e-21   1.1e-17       2      51 .]     656     706 ..     655     706 .. 0.94

  Alignments for each domain:
  == domain 1  score: 64.5 bits;  conditional E-value: 5.9e-21
  NADH_dhqG_C   2 vepasf...gkaalvaakagasgklsgaplkspiedFYmTDpISRASaTMAkC 51 
                  ve++s+   +k +lv++++g+  k++ga +k++iedFY+TD+ISR+S+TMA+C
   EEA22991.1 656 VESTSVpalSKIQLVDQNKGS--KPTGAEFKKVIEDFYFTDAISRSSPTMARC 706
                  6777777789***********..8***************************** PP

>> NADH-G_4Fe-4S_3  NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.6   0.2     1e-20   1.8e-17       1      38 [.     110     147 ..     110     149 .. 0.95
   2 ?   -3.3   1.4       3.9   6.9e+03      11      21 ..     173     183 ..     172     184 .. 0.80

  Alignments for each domain:
  == domain 1  score: 62.6 bits;  conditional E-value: 1e-20
  NADH-G_4Fe-4S_3   1 RktilellLanHpldCltCdknGnCeLQdlayelgvee 38 
                      R +++e+lLanHpldC++Cd++G+C+LQd ++++g ++
       EEA22991.1 110 REGVMEFLLANHPLDCPVCDQGGECDLQDQSMRYGADR 147
                      899********************************986 PP

  == domain 2  score: -3.3 bits;  conditional E-value: 3.9
  NADH-G_4Fe-4S_3  11 nHpldCltCdk 21 
                      n +  C+ C++
       EEA22991.1 173 NRCIHCTRCVR 183
                      67788999987 PP

>> Fer2_4  2Fe-2S iron-sulfur cluster binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.3   0.3   1.3e-18   2.4e-15       2      81 ..      32     103 ..      31     104 .. 0.93

  Alignments for each domain:
  == domain 1  score: 56.3 bits;  conditional E-value: 1.3e-18
      Fer2_4   2 rpvtltfDGkevtvpeGdtvasAllangvdvprsckygrprgelcaggeCrnClVevegepn.vracstpvedGlkvetqt 81 
                 ++v+lt+DGk+v+ ++G+ +++A+ ++gv++pr              g+Cr ClVeve+ p+ v++c  pv++G++v+t++
  EEA22991.1  32 AEVELTIDGKKVSIEAGSALIQACEKAGVTIPRKLLI---------AGNCRMCLVEVEKAPKpVASCAWPVQPGMVVKTNS 103
                 689*****************************86666.........69***********99978***************87 PP

>> Fer2  2Fe-2S iron-sulfur cluster binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8   0.2   3.7e-08   6.6e-05       2      77 ..      37      93 ..      36      94 .. 0.82
   2 ?   -1.0   0.2      0.98   1.8e+03      19      40 ..     113     134 ..     105     136 .. 0.83

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 3.7e-08
                ETTTEEEEEEEETTTHBHHHHHHHTTTTTSTTSSSS....SSSSTTEEEEEESCECTTSSSSTHHHHHTTEEEEGGGSEE CS
        Fer2  2 tidgkevevevadgettlldaaeenggidipysCgg....ggCgtClvevlegevqsdetelegeeldegklrlaCqtiv 77
                tidgk+v++e+   ++ l +a+e++ g+ ip   +     g+C++Clvev+            +++    k +++C+ +v
  EEA22991.1 37 TIDGKKVSIEA---GSALIQACEKA-GVTIP---RKlliaGNCRMCLVEVE------------KAP----KPVASCAWPV 93
                89********9...888******99.*****...66777666******977............565....3678887766 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.98
                 HHHHHHHTTTTTSTTSSSSSS.S CS
        Fer2  19 lldaaeenggidipysCgggg.C 40 
                 +++++  n+ +d p  C +gg C
  EEA22991.1 113 VMEFLLANHPLDCP-VCDQGGeC 134
                 78999999999999.9***9999 PP

>> TPP_enzyme_M  Thiamine pyrophosphate enzyme, central domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0      0.15   2.7e+02      75      87 ..     396     408 ..     386     424 .. 0.86
   2 ?    8.2   0.0     0.001       1.9       7      43 ..     465     506 ..     461     550 .. 0.74

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.15
                   HHH-SEEEEES-S CS
  TPP_enzyme_M  75 leeaDlvlalGar 87 
                   +eeaD +l++G++
    EEA22991.1 396 VEEADAILLVGTN 408
                   69*********86 PP

  == domain 2  score: 8.2 bits;  conditional E-value: 0.001
                   HHHH-SSEEEEE-CHHCHT.T...GHHHHHHHHHHHT-EE.E CS
  TPP_enzyme_M   7 llkaakrpvilvGggvars.g...aseelrelaeklgiPv.v 43 
                    l++akrp+i+vG+ +a + +   + e + +++ek+   + +
    EEA22991.1 465 KLASAKRPMIIVGSAIAEHpDaksVFETVGQFVEKHATTFrT 506
                   699***********9986543122445566666666665555 PP

>> Fer4  4Fe-4S binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   0.3    0.0019       3.4       4      16 ..     171     183 ..     168     184 .. 0.84
   2 ?    2.8   0.0     0.063   1.1e+02      16      24 .]     223     231 ..     222     231 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0019
                 ETTTSSS-THHHH CS
        Fer4   4 deekCigCGaCve 16 
                  +++Ci+C +Cv 
  EEA22991.1 171 SMNRCIHCTRCVR 183
                 5789*******96 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.063
                 HHSTTTEEE CS
        Fer4  16 evCPvgAIt 24 
                 + CPvgA+t
  EEA22991.1 223 DLCPVGALT 231
                 67*****86 PP

>> Fer4_19  Divergent 4Fe-4S mono-cluster
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6   2.2    0.0022         4       8      60 ..     168     231 ..     160     233 .. 0.68

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0022
     Fer4_19   8 iednrelCihsgnCvkglpevFdpkrkpwi...........kpdeasteeiievverCPSGALs 60 
                 i  + + Cih + Cv+ ++++    + +              +++ s e   +v++ CP GAL+
  EEA22991.1 168 IKTSMNRCIHCTRCVRFMNDIAGAPELGTTgrgndmqigtyLEQNISSELSANVIDLCPVGALT 231
                 5566788999999999555554444443333333334455556666778899999******996 PP

>> Fer4_17  4Fe-4S dicluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   0.3        10   1.8e+04       5       9 ..      72      76 ..      71      78 .. 0.62
   2 ?   11.1   1.4   0.00025      0.45      10      54 ..     126     183 ..     122     184 .. 0.67

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 10
     Fer4_17  5 CgyCl 9 
                C++Cl
  EEA22991.1 72 CRMCL 76
                67775 PP

  == domain 2  score: 11.1 bits;  conditional E-value: 0.00025
     Fer4_17  10 peCpsyeaydnepkkllraaklglleeaeke.............ekaslCieCgeCer 54 
                 p+C ++ + d + +++++ a  g+++e+e +             + +++Ci+C +C+r
  EEA22991.1 126 PVCDQGGECDLQDQSMRYGADRGRFHETEGKravedknigplikTSMNRCIHCTRCVR 183
                 2355555577788888888877544443333344455677888679**********86 PP

>> Fer4_4  4Fe-4S binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.5   0.2       2.9   5.2e+03       6      10 ..     124     128 ..     123     128 .. 0.86
   2 ?    9.5   1.6   0.00083       1.5       2      13 ..     173     184 ..     172     184 .. 0.90

  Alignments for each domain:
  == domain 1  score: -1.5 bits;  conditional E-value: 2.9
      Fer4_4   6 gCgsC 10 
                 +C++C
  EEA22991.1 124 DCPVC 128
                 8***9 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.00083
      Fer4_4   2 erCigCgsCvaa 13 
                 +rCi+C +Cv++
  EEA22991.1 173 NRCIHCTRCVRF 184
                 8*********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (735 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       444  (0.0247643); expected 358.6 (0.02)
Passed bias filter:                      406  (0.0226449); expected 358.6 (0.02)
Passed Vit filter:                        47  (0.00262145); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              10  [number of targets reported over threshold]
# CPU time: 0.65u 0.31s 00:00:00.96 Elapsed: 00:00:00.48
# Mc/sec: 4637.56
//
Query:       EEA22992.1  [L=327]
Description: ketoreductase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
      9e-47  159.7   0.1      5e-45  154.0   0.1    2.0  1  Aldo_ket_red  Aldo/keto reductase family
  ------ inclusion threshold ------
       0.16   12.3   0.1       0.78   10.1   0.0    2.0  2  PurL_C        Phosphoribosylformylglycinamidine synthase II C


Domain annotation for each model (and alignments):
>> Aldo_ket_red  Aldo/keto reductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  154.0   0.1   5.5e-49     5e-45      15     292 ..      70     307 ..      53     309 .. 0.91

  Alignments for each domain:
  == domain 1  score: 154.0 bits;  conditional E-value: 5.5e-49
                   S-HHHHHHHHHHHHHTT--EEE--TT-TTTHHHHHHHHHHHH-TTTGGG-EEEEEE--SSSTTSSSS-HHHHHHHHHHHHHHHT-S-EEEEEE-S-- CS
  Aldo_ket_red  15 iskeealellrraleaGinffDtAevYgkgqseellGealkksrkkreeviiatKvdlrdaeiksglskeniresleeslkrLgtdyvDllllHrpd 111
                   i+  e +e +++a++ G+ ++D AevY     e +lG a+k+s++ re+++++tKv         + + ++i  ++e+slk+L++dyvDl+l+H p+
    EEA22992.1  70 IN-RELVESIKTAIKLGYHHLDGAEVY---GTEPELGVAIKESGVAREKLFVVTKV---------YPNIDDIPSAIEQSLKKLQLDYVDLYLIHAPF 153
                   44.4677889*****************...88999*********************.........99****************************** PP

                   TTS-...HHHHHHHHHHHHHTTSEEEEEEES--HHHHHHHHHTTT--EEEEE-B-BTT-HHHHTTHHHHHHHTT-EEEEBSTTGGGTTGTTTSS--- CS
  Aldo_ket_red 112 pslp..sieevldaleelvkeGkiraiGvSnfsveqlekakkkkkvkivavqveynllreleeegllelckkkgvpliaysplggGlltgkyqseed 206
                    + +  ++ ++++a+e+++++Gk++ iGvSn++ ++le  +k++k++++++q+e++++  l++  ll++ k+kg+++ ay+pl    +         
    EEA22992.1 154 KANSdkELQDTWAAIEKVKESGKAKEIGVSNYTKAHLETTLKTAKIPPAINQIEFHPY--LQHGDLLDYHKEKGIATSAYGPLTPVTRA-A------ 241
                   99998899**************************************************..***********************943333.1...... PP

                   SSSCCC-------TS-HHHHHHHHHHHHHHHHTT--HHHHHHHHHTTSTT-SEEEE--SSHHHHHHHHGGGG----HHHHHHHHHH CS
  Aldo_ket_red 207 kedkeprkdlkrdertsknldaaeelselakehgvslaqlalryalsqpavgivipgasnieqlednldalelklseeevaeldel 292
                                        +++ l  lak++ v++  +a+r+a+  +++ i+i  +s+ ++l++ l+a++++l+++ev+++ el
    EEA22992.1 242 G------------------GPLDDVLAGLAKKYAVTPGDVAIRWAI--ERGAIAITTSSKESRLTEYLRAVKFNLTPKEVEQISEL 307
                   1..................278999*********************..***********************************987 PP

>> PurL_C  Phosphoribosylformylglycinamidine synthase II C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.0   8.7e-05      0.78      17      73 ..     153     212 ..     143     216 .. 0.79
   2 ?   -1.3   0.0       0.3   2.7e+03      29      64 ..     265     298 ..     263     305 .. 0.64

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 8.7e-05
                 --GGGHHHH...HHHHHHHHHTT.-EEE--TTSS-HHHHHHHHTT-EEEE------..SS- CS
      PurL_C  17 felerekkl...Wseirklvekg.afvvsssdyskrttlenalkglklnvklpelrhePvh 73 
                 f+ + +k+l   W++i+k+ e g a  +  s+y+ +++le+ lk+ k+ + ++++  +P  
  EEA22992.1 153 FKANSDKELqdtWAAIEKVKESGkAKEIGVSNYT-KAHLETTLKTAKIPPAINQIEFHPYL 212
                 666666766566******9987625678888886.689****************9999865 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.3
                 HHHHHHTT-EEE--TTSS-HHHHHHHHTT-EEEE-- CS
      PurL_C  29 irklvekgafvvsssdyskrttlenalkglklnvkl 64 
                 ir  +e+ga  ++    sk + l ++l+++k+n+  
  EEA22992.1 265 IRWAIERGAIAIT--TSSKESRLTEYLRAVKFNLTP 298
                 6666677765554..446667777777888887755 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (327 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       568  (0.0316805); expected 358.6 (0.02)
Passed bias filter:                      487  (0.0271627); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.29s 00:00:00.84 Elapsed: 00:00:00.47
# Mc/sec: 2080.90
//
Query:       EEA22993.1  [L=647]
Description: YdiU domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   6.8e-132  440.6   0.0   9.2e-132  440.1   0.0    1.0  1  UPF0061   Uncharacterized ACR, YdiU/UPF0061 family


Domain annotation for each model (and alignments):
>> UPF0061  Uncharacterized ACR, YdiU/UPF0061 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  440.1   0.0  5.2e-136  9.2e-132      17     464 ..      79     609 ..      72     612 .. 0.88

  Alignments for each domain:
  == domain 1  score: 440.1 bits;  conditional E-value: 5.2e-136
     UPF0061  17 dfydeveaaefpkkilrvrndalleelgldeeevkdeelieifgke........kgiepflalrYhGyQFGeynpqLGDGRgfllgqvrdkd.gelydf 106
                 ++y+ v+++++++ +l+  + + +e+lgl++ e k e+++++ +++         g+ p+ a+ Y G+QFG +++qLGDGR++ l ++ + + +  y++
  EEA22993.1  79 AMYTYVRPETAEEPELLGVSPRAMEDLGLQPGEEKTEDFVSLVAGNkilwneeeGGVYPW-AQCYGGWQFGAWAGQLGDGRAISLCELTNPStNVRYEL 176
                 56889999999999999999999*******************999999*999988899*9.***************************997736789** PP

     UPF0061 107 glKGsGlTPySRsaDGrlvLksgvREvlasealhklgvrtsralslie.tgekllRedePspersavvvRlarshiRfGtferlkylkrldllkkLldy 204
                 +lKG+G+TPySR+aDG++vL+s++RE+++seal +lg++t+ralsl+  +++k+lRe     e++a+v R+a+s++R+G+f+ l+ +++ dl+++L+ y
  EEA22993.1 177 QLKGAGRTPYSRFADGKAVLRSSIREYVVSEALDALGIPTTRALSLTLlPKSKVLRE---RIEPGAIVARFAQSWLRIGSFDILHSRNERDLVRQLATY 272
                 ***********************************************99********...*************************************** PP

     UPF0061 205 vieeyypel........adee...............................ekyaqfyaelvervAelvAqWmaaGFchgVlNTDNmsilGeslDYGP 264
                 + e+ +p +                                           ++++++y+e+v+r+A++vA W+a+GF++gVlNTDN+si G+slD+GP
  EEA22993.1 273 IAEDVFPGWeslpgvvnL--PnegsssgdvnvddpprgipaaelqgkegqeeNRFTRLYREIVRRNAKTVAAWQAYGFMNGVLNTDNTSIFGLSLDFGP 369
                 ****99988555555540..04455555555666666666666666666666*********************************************** PP

     UPF0061 265 yaFldkydpkftaayfDyagrYsyanQpsiilwNLeqlaeplalli...........................eaeeleealeeykevyttkYaqlmlk 336
                 +aF+d++dp++t++++D++ rYsy+nQps+i+wNL +l e++  li                           + + ++++ eey+ v++++Y +lm++
  EEA22993.1 370 FAFMDNFDPSYTPNHDDHYLRYSYKNQPSVIWWNLVRLGEAFGELIggaervddeefitkgvteefgqilikrAETIINRTCEEYRAVFKNEYVRLMSR 468
                 **********************************************9999999999999999999999988877777888888**************** PP

     UPF0061 337 kLGleklsekekefdselleellelLqetqvdYneffveLaeskskkwrdeaesileese.......kelee.........ekleeWrelYkklleele 419
                 +LGl  l++ke++  ++l++ell+ +++ ++d+n+ff++L++  +++ +++++     ++                     +++ +W +l+k++++e  
  EEA22993.1 469 RLGL--LTSKESD-FETLFSELLDTMEHLELDFNHFFRRLSDIGTEELETDEQRQAIAKRffhnegvG---GvgnteestcKRIAAWLSLWKDRIHEDW 561
                 ****..5555555.569*************************99999885544432222224444450...055555667799*********9999765 PP

     UPF0061 420 ed...eleeraerlkkvNpktvllrplieeviekiaeeddlsplkkll 464
                 ++   + +er+e +k+vNpk+++++++++evie+++++ d + l +++
  EEA22993.1 562 KQdgrTDQERKELMKSVNPKFIPRSWILDEVIERVEHKGDRQILGRVM 609
                 54233678999*****************************99998776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (647 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       515  (0.0287244); expected 358.6 (0.02)
Passed bias filter:                      474  (0.0264376); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.28s 00:00:00.90 Elapsed: 00:00:00.45
# Mc/sec: 4288.70
//
Query:       EEA22994.1  [L=183]
Description: zinc knuckle domain protein (Byr3), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    2.3e-53  176.0  65.3    4.9e-09   35.9   1.8    7.2  7  zf-CCHC    Zinc knuckle
      1e-11   44.4  43.1      0.018   14.8   1.3    7.1  7  zf-CCHC_4  Zinc knuckle
    1.8e-06   27.5  44.6       0.08   12.7   1.0    7.1  7  zf-CCHC_5  GAG-polyprotein viral zinc-finger
    1.6e-05   24.8  53.7      0.052   13.5   1.4    7.0  7  zf-CCHC_3  Zinc knuckle
  ------ inclusion threshold ------
        2.3    8.1  49.2        0.5   10.2   1.6    7.0  7  zf-CCHC_6  Zinc knuckle


Domain annotation for each model (and alignments):
>> zf-CCHC  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.8   3.2   4.8e-10   1.7e-06       1      18 []       8      25 ..       8      25 .. 0.94
   2 !   30.3   3.2   7.6e-11   2.7e-07       1      18 []      29      46 ..      29      46 .. 0.94
   3 !   31.9   3.0   2.4e-11   8.5e-08       2      18 .]      52      68 ..      51      68 .. 0.92
   4 !   31.5   2.6   3.3e-11   1.2e-07       2      18 .]      92     108 ..      91     108 .. 0.92
   5 !   30.7   3.7     6e-11   2.1e-07       2      18 .]     125     141 ..     124     141 .. 0.94
   6 !   35.9   1.8   1.4e-12   4.9e-09       1      17 [.     143     159 ..     143     160 .. 0.93
   7 !   24.9   1.7   3.9e-09   1.4e-05       1      18 []     166     183 .]     166     183 .] 0.94

  Alignments for each domain:
  == domain 1  score: 27.8 bits;  conditional E-value: 4.8e-10
                SCTSSSSSSSSTTTTSTS CS
     zf-CCHC  1 rkCynCGepGHiardCpk 18
                r+C+nCGep H+ardCpk
  EEA22994.1  8 RGCFNCGEPSHQARDCPK 25
                58***************7 PP

  == domain 2  score: 30.3 bits;  conditional E-value: 7.6e-11
                SCTSSSSSSSSTTTTSTS CS
     zf-CCHC  1 rkCynCGepGHiardCpk 18
                ++CynCG+ GH++r+C++
  EEA22994.1 29 PTCYNCGGQGHVSRECTQ 46
                58**************97 PP

  == domain 3  score: 31.9 bits;  conditional E-value: 2.4e-11
                CTSSSSSSSSTTTTSTS CS
     zf-CCHC  2 kCynCGepGHiardCpk 18
                 Cy+CG++GHi+rdC +
  EEA22994.1 52 SCYRCGQTGHISRDCQQ 68
                6**************86 PP

  == domain 4  score: 31.5 bits;  conditional E-value: 3.3e-11
                 CTSSSSSSSSTTTTSTS CS
     zf-CCHC   2 kCynCGepGHiardCpk 18 
                  Cy+CG++GHiar+C++
  EEA22994.1  92 ECYKCGQVGHIARNCSQ 108
                 7**************86 PP

  == domain 5  score: 30.7 bits;  conditional E-value: 6e-11
                 CTSSSSSSSSTTTTSTS CS
     zf-CCHC   2 kCynCGepGHiardCpk 18 
                 +Cy CG+ GH+ardC++
  EEA22994.1 125 TCYSCGGYGHMARDCTQ 141
                 8**************97 PP

  == domain 6  score: 35.9 bits;  conditional E-value: 1.4e-12
                 SCTSSSSSSSSTTTTST CS
     zf-CCHC   1 rkCynCGepGHiardCp 17 
                 +kCynCGe+GH++rdC+
  EEA22994.1 143 QKCYNCGEVGHVSRDCT 159
                 59**************8 PP

  == domain 7  score: 24.9 bits;  conditional E-value: 3.9e-09
                 SCTSSSSSSSSTTTTSTS CS
     zf-CCHC   1 rkCynCGepGHiardCpk 18 
                 r+Cy+C +pGH+ + Cp+
  EEA22994.1 166 RVCYKCKQPGHVQSACPN 183
                 58***************6 PP

>> zf-CCHC_4  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.1   0.4    0.0003       1.1      33      49 .]       9      25 ..       7      25 .. 0.90
   2 !   10.8   0.9   8.6e-05      0.31      34      48 ..      31      45 ..      28      46 .. 0.92
   3 !    7.6   0.8   0.00084         3      33      48 ..      52      67 ..      50      68 .. 0.90
   4 !   10.8   0.9   8.6e-05      0.31      34      48 ..      93     107 ..      90     108 .. 0.91
   5 !   10.7   1.0   9.4e-05      0.34      32      48 ..     124     140 ..     123     141 .. 0.90
   6 !   14.8   1.3     5e-06     0.018      32      48 ..     143     159 ..     142     160 .. 0.90
   7 !    8.9   0.2   0.00033       1.2      32      48 ..     166     182 ..     165     183 .] 0.93

  Alignments for each domain:
  == domain 1  score: 9.1 bits;  conditional E-value: 0.0003
   zf-CCHC_4 33 fCyiCgvlGHsdkrCdk 49
                 C++Cg   H++++C+k
  EEA22994.1  9 GCFNCGEPSHQARDCPK 25
                5**************95 PP

  == domain 2  score: 10.8 bits;  conditional E-value: 8.6e-05
   zf-CCHC_4 34 CyiCgvlGHsdkrCd 48
                Cy+Cg  GH+ ++C 
  EEA22994.1 31 CYNCGGQGHVSRECT 45
                **************6 PP

  == domain 3  score: 7.6 bits;  conditional E-value: 0.00084
   zf-CCHC_4 33 fCyiCgvlGHsdkrCd 48
                 Cy Cg  GH  ++C+
  EEA22994.1 52 SCYRCGQTGHISRDCQ 67
                5**************7 PP

  == domain 4  score: 10.8 bits;  conditional E-value: 8.6e-05
   zf-CCHC_4  34 CyiCgvlGHsdkrCd 48 
                 Cy Cg +GH +++C+
  EEA22994.1  93 CYKCGQVGHIARNCS 107
                 **************7 PP

  == domain 5  score: 10.7 bits;  conditional E-value: 9.4e-05
   zf-CCHC_4  32 sfCyiCgvlGHsdkrCd 48 
                 + Cy+Cg  GH +++C 
  EEA22994.1 124 QTCYSCGGYGHMARDCT 140
                 57**************6 PP

  == domain 6  score: 14.8 bits;  conditional E-value: 5e-06
   zf-CCHC_4  32 sfCyiCgvlGHsdkrCd 48 
                 ++Cy+Cg +GH+ ++C 
  EEA22994.1 143 QKCYNCGEVGHVSRDCT 159
                 68**************6 PP

  == domain 7  score: 8.9 bits;  conditional E-value: 0.00033
   zf-CCHC_4  32 sfCyiCgvlGHsdkrCd 48 
                 ++Cy C   GH+ ++C+
  EEA22994.1 166 RVCYKCKQPGHVQSACP 182
                 79**************8 PP

>> zf-CCHC_5  GAG-polyprotein viral zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    6.1   2.2    0.0025         9       5      19 ..      10      24 ..       7      27 .. 0.90
   2 !    5.9   0.4    0.0029        10       5      18 ..      31      44 ..      28      46 .. 0.92
   3 !   12.7   1.0   2.2e-05      0.08       4      19 ..      52      67 ..      49      75 .. 0.85
   4 !    9.4   0.8   0.00024      0.87       5      18 ..      93     106 ..      90     108 .. 0.93
   5 !    7.1   0.5    0.0012       4.4       4      18 ..     125     139 ..     122     143 .. 0.87
   6 !    8.9   0.2   0.00032       1.2       4      20 ..     144     160 ..     141     165 .. 0.87
   7 !    6.0   1.6    0.0027       9.6       4      18 ..     167     181 ..     164     182 .. 0.91

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.0025
                -TTT-SSBS-TTT-- CS
   zf-CCHC_5  5 CpRCkkgkHwardCh 19
                C  C+   H ardC 
  EEA22994.1 10 CFNCGEPSHQARDCP 24
                999***********5 PP

  == domain 2  score: 5.9 bits;  conditional E-value: 0.0029
                -TTT-SSBS-TTT- CS
   zf-CCHC_5  5 CpRCkkgkHwardC 18
                C  C+   H+ r+C
  EEA22994.1 31 CYNCGGQGHVSREC 44
                999*********** PP

  == domain 3  score: 12.7 bits;  conditional E-value: 2.2e-05
                B-TTT-SSBS-TTT-- CS
   zf-CCHC_5  4 lCpRCkkgkHwardCh 19
                 C RC++  H  rdC+
  EEA22994.1 52 SCYRCGQTGHISRDCQ 67
                6**************7 PP

  == domain 4  score: 9.4 bits;  conditional E-value: 0.00024
                 -TTT-SSBS-TTT- CS
   zf-CCHC_5   5 CpRCkkgkHwardC 18 
                 C +C++  H ar+C
  EEA22994.1  93 CYKCGQVGHIARNC 106
                 ************** PP

  == domain 5  score: 7.1 bits;  conditional E-value: 0.0012
                 B-TTT-SSBS-TTT- CS
   zf-CCHC_5   4 lCpRCkkgkHwardC 18 
                  C  C+   H ardC
  EEA22994.1 125 TCYSCGGYGHMARDC 139
                 6999***9******* PP

  == domain 6  score: 8.9 bits;  conditional E-value: 0.00032
                 B-TTT-SSBS-TTT--- CS
   zf-CCHC_5   4 lCpRCkkgkHwardChs 20 
                  C  C+   H+ rdC  
  EEA22994.1 144 KCYNCGEVGHVSRDCTT 160
                 699************75 PP

  == domain 7  score: 6.0 bits;  conditional E-value: 0.0027
                 B-TTT-SSBS-TTT- CS
   zf-CCHC_5   4 lCpRCkkgkHwardC 18 
                  C +Ck+  H+ + C
  EEA22994.1 167 VCYKCKQPGHVQSAC 181
                 6************99 PP

>> zf-CCHC_3  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.5      0.03   1.1e+02       3      24 ..       6      27 ..       4      30 .. 0.80
   2 !   12.3   2.9   3.6e-05      0.13       3      23 ..      27      48 ..      25      52 .. 0.81
   3 !   13.5   1.4   1.5e-05     0.052       4      26 ..      50      70 ..      47      78 .. 0.81
   4 !    9.0   1.8   0.00038       1.3       4      24 ..      90     108 ..      88     114 .. 0.82
   5 !    6.3   6.8    0.0027       9.5       4      27 ..     123     145 ..     120     147 .. 0.82
   6 !    8.4   0.6   0.00058       2.1       4      23 ..     142     163 ..     140     167 .. 0.79
   7 !    7.5   1.5    0.0011         4       1      17 [.     162     178 ..     162     183 .] 0.82

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.03
   zf-CCHC_3  3 asaaCQkClkkGHwtYECknag 24
                +s  C +C+++ H +  C+++g
  EEA22994.1  6 GSRGCFNCGEPSHQARDCPKKG 27
                567799*******999999544 PP

  == domain 2  score: 12.3 bits;  conditional E-value: 3.6e-05
   zf-CCHC_3  3 asaaCQkClkkGHwtYECkn.a 23
                ++ +C +C+++GH + EC++  
  EEA22994.1 27 GTPTCYNCGGQGHVSRECTQaP 48
                6789***************742 PP

  == domain 3  score: 13.5 bits;  conditional E-value: 1.5e-05
   zf-CCHC_3  4 saaCQkClkkGHwtYECknager 26
                 + C +C+++GH +  C++  ++
  EEA22994.1 50 EKSCYRCGQTGHISRDCQQ--SA 70
                688***************5..33 PP

  == domain 4  score: 9.0 bits;  conditional E-value: 0.00038
   zf-CCHC_3   4 saaCQkClkkGHwtYECknag 24 
                 ++ C kC++ GH +  C   +
  EEA22994.1  90 GQECYKCGQVGHIARNCS--Q 108
                 578**********99998..3 PP

  == domain 5  score: 6.3 bits;  conditional E-value: 0.0027
   zf-CCHC_3   4 saaCQkClkkGHwtYECknagerk 27 
                 +++C  C+++GH++  C+ +g++ 
  EEA22994.1 123 QQTCYSCGGYGHMARDCT-QGQKC 145
                 679***************.55555 PP

  == domain 6  score: 8.4 bits;  conditional E-value: 0.00058
   zf-CCHC_3   4 saaCQkClkkGHwtYECkn..a 23 
                 ++ C +C++ GH +  C+   +
  EEA22994.1 142 GQKCYNCGEVGHVSRDCTTeaN 163
                 678**************96544 PP

  == domain 7  score: 7.5 bits;  conditional E-value: 0.0011
   zf-CCHC_3   1 anasaaCQkClkkGHwt 17 
                 an+  +C kC ++GH  
  EEA22994.1 162 ANGERVCYKCKQPGHVQ 178
                 68899**********75 PP

>> zf-CCHC_6  Zinc knuckle
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.7   1.6     0.031   1.1e+02       4      23 ..      10      27 ..       8      30 .. 0.88
   2 ?    6.6   1.2     0.002       7.1       4      15 ..      31      42 ..      30      46 .. 0.85
   3 ?    2.5   0.7     0.038   1.4e+02       4      15 ..      53      64 ..      51      68 .. 0.86
   4 ?    7.5   1.2     0.001       3.7       4      16 ..      93     105 ..      92     107 .. 0.91
   5 ?   10.2   1.6   0.00014       0.5       4      15 ..     126     137 ..     124     140 .. 0.89
   6 ?   10.2   0.7   0.00015      0.52       3      15 ..     144     156 ..     143     159 .. 0.87
   7 ?   -0.6   1.0      0.34   1.2e+03       4      20 ..     168     182 ..     166     183 .] 0.76

  Alignments for each domain:
  == domain 1  score: 2.7 bits;  conditional E-value: 0.031
   zf-CCHC_6  4 CknCGAFGHtarSkrCPmkc 23
                C nCG   H+a  + CP k 
  EEA22994.1 10 CFNCGEPSHQA--RDCPKKG 27
                99*******99..89**985 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.002
   zf-CCHC_6  4 CknCGAFGHtar 15
                C nCG  GH  r
  EEA22994.1 31 CYNCGGQGHVSR 42
                9********875 PP

  == domain 3  score: 2.5 bits;  conditional E-value: 0.038
   zf-CCHC_6  4 CknCGAFGHtar 15
                C  CG  GH  r
  EEA22994.1 53 CYRCGQTGHISR 64
                999******875 PP

  == domain 4  score: 7.5 bits;  conditional E-value: 0.001
   zf-CCHC_6   4 CknCGAFGHtarS 16 
                 C +CG  GH ar+
  EEA22994.1  93 CYKCGQVGHIARN 105
                 99*********97 PP

  == domain 5  score: 10.2 bits;  conditional E-value: 0.00014
   zf-CCHC_6   4 CknCGAFGHtar 15 
                 C  CG +GH+ar
  EEA22994.1 126 CYSCGGYGHMAR 137
                 99*********7 PP

  == domain 6  score: 10.2 bits;  conditional E-value: 0.00015
   zf-CCHC_6   3 KCknCGAFGHtar 15 
                 KC nCG  GH  r
  EEA22994.1 144 KCYNCGEVGHVSR 156
                 9*********875 PP

  == domain 7  score: -0.6 bits;  conditional E-value: 0.34
   zf-CCHC_6   4 CknCGAFGHtarSkrCP 20 
                 C +C   GH    + CP
  EEA22994.1 168 CYKCKQPGHVQ--SACP 182
                 88888889987..6677 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (183 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       674  (0.0375927); expected 358.6 (0.02)
Passed bias filter:                      151  (0.00842211); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.47u 0.29s 00:00:00.76 Elapsed: 00:00:00.46
# Mc/sec: 1207.75
//
Query:       EEA22995.1  [L=561]
Description: WD domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.9e-09   36.7   0.2    6.5e-09   35.5   0.2    1.7  1  F-box-like  F-box-like
    4.6e-09   35.9   0.4    1.2e-08   34.6   0.4    1.8  1  F-box       F-box domain


Domain annotation for each model (and alignments):
>> F-box-like  F-box-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.5   0.2   7.3e-13   6.5e-09       6      47 ..      36      76 ..      31      77 .. 0.94

  Alignments for each domain:
  == domain 1  score: 35.5 bits;  conditional E-value: 7.3e-13
  F-box-like  6 dEiLlqIFsyLppsdLlrlalVCrrWrrvaldtplLWrrlvl 47
                dEiLlqI+s ++  +L+ + +V++r++ +a d  +LW+r ++
  EEA22995.1 36 DEILLQILSSVSIDTLVKCQRVSKRFHALAGDS-ELWKRRYF 76
                8********99999****************999.*****987 PP

>> F-box  F-box domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.6   0.4   1.3e-12   1.2e-08       3      46 ..      31      74 ..      29      76 .. 0.95

  Alignments for each domain:
  == domain 1  score: 34.6 bits;  conditional E-value: 1.3e-12
                HHHS-HHHHHHHHHTS-HHHHHHHCTT-HHHHHHHTTHHHHHHH CS
       F-box  3 lsrLPsevlrhILerLplsdllalrrVSkgwrilidsdrlwcks 46
                +s L++e+l++IL++++  +l+ + rVSk+++ l  + +lw+++
  EEA22995.1 31 ISKLSDEILLQILSSVSIDTLVKCQRVSKRFHALAGDSELWKRR 74
                89***************************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (561 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       342  (0.0190752); expected 358.6 (0.02)
Passed bias filter:                      283  (0.0157845); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.55u 0.30s 00:00:00.85 Elapsed: 00:00:00.46
# Mc/sec: 3675.78
//
Query:       EEA22996.1  [L=674]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    6.9e-33  114.1   0.2    6.9e-33  114.1   0.2    3.0  2  SAE2             DNA repair protein endonuclease SAE2/CtIP C-
     0.0023   16.9   2.3     0.0046   15.9   2.3    1.5  1  Fmp27_WPPW       RNA pol II promoter Fmp27 protein domain
      0.003   18.1   9.7      0.011   16.3   9.7    2.1  1  Ribosomal_60s    60s Acidic ribosomal protein
  ------ inclusion threshold ------
       0.17   12.0   7.6        1.1    9.3   3.2    2.8  2  ADIP             Afadin- and alpha -actinin-Binding
       0.45   10.5   3.5         12    6.0   0.1    3.5  3  Ribosomal_L29    Ribosomal L29 protein
        1.1    7.5   6.4        1.6    6.9   6.4    1.2  1  CDC45            CDC45-like protein
        1.4    9.8  14.6          7    7.6  14.6    2.3  1  WRNPLPNID        Putative WW-binding domain and destruction b
        1.6    9.4   9.3        1.9    9.2   3.1    3.2  3  AATF-Che1        Apoptosis antagonizing transcription factor
        2.5    7.4  10.9        4.5    6.5   6.4    2.4  2  DUF3450          Protein of unknown function (DUF3450)
        8.7    4.3  15.2         20    3.1  15.2    1.6  1  DNA_pol_phi      DNA polymerase phi
        9.6    5.4  13.0         17    4.6  13.0    1.3  1  NOA36            NOA36 protein


Domain annotation for each model (and alignments):
>> SAE2  DNA repair protein endonuclease SAE2/CtIP C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.9   3.3       2.1   3.5e+03      35      74 ..      58      97 ..      16     123 .. 0.50
   2 !  114.1   0.2   4.2e-36   6.9e-33       1     111 []     531     635 ..     531     635 .. 0.98

  Alignments for each domain:
  == domain 1  score: -0.9 bits;  conditional E-value: 2.1
        SAE2 35 earkeeptaskeeedkklleeklgdeayklakmsseerqe 74
                + + ++ +++k++++  +++e+ g+e+++ ++ ++ee++e
  EEA22996.1 58 QSELADLRHYKKATNPGAQDEEEGEEEEEGEEEEEEEEEE 97
                2222222333333333333333333322222222222222 PP

  == domain 2  score: 114.1 bits;  conditional E-value: 4.2e-36
        SAE2   1 aFdevvrgkderkclpgCtkpeCcgkkfravaelearkeeptaskeeedkklleeklgdeayklakmsseerqeleieakkkklankfgrHRhaferak 99 
                 aF++vvrg +erkclpgC++ +Ccg+kfra++++++      ++++e++++llee+lgd++++l++ms+++ + l+ieak+ +lan+fg+HRha+era+
  EEA22996.1 531 AFKDVVRG-SERKCLPGCMRADCCGDKFRAMVRATG-----IKYDAEKHRALLEEHLGDRKSTLQQMSEQTLNGLLIEAKATQLANQFGKHRHAYERAR 623
                 7*******.88***********************99.....788999**************************************************** PP

        SAE2 100 sPpgFWeidFPt 111
                 sPpgFW++d+P+
  EEA22996.1 624 SPPGFWRTDMPS 635
                 ***********6 PP

>> Fmp27_WPPW  RNA pol II promoter Fmp27 protein domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   2.3   2.8e-06    0.0046     177     336 ..       5     210 ..       1     256 [. 0.74

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 2.8e-06
  Fmp27_WPPW 177 eeRleeleeqiekleekleelelksekedeelkeeieelekeikelkeklefletlledlkeseesse.........eeeskskelsaastsesfseld 266
                  +Rl ++++++++ ++++ +++ +++ + e+l+++i++le +    +++++ l++ l dl++ +++++         e         ++++ e+++e +
  EEA22996.1   5 IQRLISISKDLDTARNEVAKQDVQHQYDAERLQKKIRTLEGQRGCDQKRIKKLQSELADLRHYKKATNpgaqdeeegE---------EEEEGEEEEEEE 94 
                 5899*****************9999999**********************************9998887766543321.........222222222222 PP

  Fmp27_WPPW 267 e.............................................lasseesaseFknRFiihniqlkwnnslRnillrylhqvsqrrgfvyymsrka 320
                 e                                             ++s ++++ ++++ +     ++k+ +slR  + +   + +q +     +s + 
  EEA22996.1  95 EeeeeegddgsddriievklqklkdtydpanitalawpeghldvpiVSSIQRLKDSYNDLYKETAALVKIMSSLRAQVKHHKRRAEQWQRWCAGLSAQN 193
                 212234556677788888888888888888888888888888888888888888888888888888888888888888777777777766655555444 PP

  Fmp27_WPPW 321 vk.fiedlveeqekskk 336
                 +   i ++v++q+++ +
  EEA22996.1 194 MApPIAQVVRQQNDAPS 210
                 43156666666666554 PP

>> Ribosomal_60s  60s Acidic ribosomal protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.3   9.7   6.8e-06     0.011      37      84 ..      52     104 ..      14     106 .. 0.62

  Alignments for each domain:
  == domain 1  score: 16.3 bits;  conditional E-value: 6.8e-06
                    XXXXXXXXXXX.....XXXXXXXXXXXXXXXXXXXXXXXXXXXX.XX--SS-- CS
  Ribosomal_60s  37 ellangaakla.....aaaaaaaaaaaaaaaaaaaeekkkeeeeeEeedddmG 84 
                    + +++ ++ la       a+ + a+ +++++++++ e+++eeeeeEee+ d G
     EEA22996.1  52 KRIKKLQSELAdlrhyKKATNPGAQDEEEGEEEEEGEEEEEEEEEEEEEGDDG 104
                    45555555555666555556666666666666666666666666566666766 PP

>> ADIP  Afadin- and alpha -actinin-Binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   3.2    0.0007       1.1      41     105 ..       5      69 ..       3      82 .. 0.81
   2 ?    3.7   0.1     0.036        59      75     110 ..     143     178 ..     140     195 .. 0.60

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.0007
        ADIP  41 iysLlqardrdleqreslnetirkleaeierlqskierlktqleqlerelalvqakerqlekklk 105
                 i +L+  ++    +r++++++  + +++ erlq+ki+ l+ q    +++++ +q+++++l+   k
  EEA22996.1   5 IQRLISISKDLDTARNEVAKQDVQHQYDAERLQKKIRTLEGQRGCDQKRIKKLQSELADLRHYKK 69 
                 55555555555567999999999*********************999999999999999886555 PP

  == domain 2  score: 3.7 bits;  conditional E-value: 0.036
        ADIP  75 kierlktqleqlerelalvqakerqlekklktleqk 110
                 +i+rlk+++ +l +e+a++ +   +l++++k+ ++ 
  EEA22996.1 143 SIQRLKDSYNDLYKETAALVKIMSSLRAQVKHHKRR 178
                 566666666666666666666666666665554443 PP

>> Ribosomal_L29  Ribosomal L29 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.1       1.7   2.7e+03      15      31 ..      15      31 ..      11      45 .. 0.50
   2 ?    6.0   0.1    0.0071        12      12      36 ..      51      72 ..      51      76 .. 0.85
   3 ?    3.1   0.1     0.057        93       2      27 ..     587     612 ..     586     621 .. 0.85

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 1.7
                   HHHHHHHHHHHHHHHHH CS
  Ribosomal_L29 15 lkelkkeLfnLrfqkat 31
                   l+ +++e  +  +q++ 
     EEA22996.1 15 LDTARNEVAKQDVQHQY 31
                   55555555555555543 PP

  == domain 2  score: 6.0 bits;  conditional E-value: 0.0071
                   HHHHHHHHHHHHHHHHHHHHTSSS- CS
  Ribosomal_L29 12 keklkelkkeLfnLrfqkatgqlen 36
                   ++++k+l+ eL +Lr +k++    n
     EEA22996.1 51 QKRIKKLQSELADLRHYKKAT---N 72
                   699************998866...3 PP

  == domain 3  score: 3.1 bits;  conditional E-value: 0.057
                    HHHHS-HHHHHHHHHHHHHHHHHHHH CS
  Ribosomal_L29   2 elrelsdeeLkeklkelkkeLfnLrf 27 
                     l+++s++ L+  l e+k+ ++   f
     EEA22996.1 587 TLQQMSEQTLNGLLIEAKATQLANQF 612
                    689***************99887666 PP

>> CDC45  CDC45-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   6.4   0.00098       1.6     115     162 ..      56     106 ..      33     187 .. 0.62

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.00098
       CDC45 115 eleeere...ayealeeeeesdeedeeeeeeddddeeeeeeeeedeedeee 162
                 +l++e      y++ ++   +dee+ eeeee +++eeeeeeeee+++d ++
  EEA22996.1  56 KLQSELAdlrHYKKATNPGAQDEEEGEEEEEGEEEEEEEEEEEEEGDDGSD 106
                 444433322234444443333333322222222222222222222222222 PP

>> WRNPLPNID  Putative WW-binding domain and destruction box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.6  14.6    0.0043         7      15      61 ..      56     104 ..      52     111 .. 0.51

  Alignments for each domain:
  == domain 1  score: 7.6 bits;  conditional E-value: 0.0043
   WRNPLPNID  15 eidleLeeLllldse....aeessege.svdedeeaeeeeeeeeeeedeeds 61 
                 ++++eL +L   ++     a   +++e  ++e+e +eeeeeeeeeee+ +d+
  EEA22996.1  56 KLQSELADLRHYKKAtnpgA---QDEEeGEEEEEGEEEEEEEEEEEEEGDDG 104
                 68899999998888864332...32222222333333333333333334444 PP

>> AATF-Che1  Apoptosis antagonizing transcription factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   3.1    0.0012       1.9      58     128 ..      50     124 ..       4     131 .. 0.49
   2 ?    2.1   0.0      0.18   2.9e+02      49      87 ..     145     202 ..     137     259 .. 0.69
   3 ?   -1.1   0.2       1.7   2.8e+03      89     119 ..     470     500 ..     446     503 .. 0.70

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0012
   AATF-Che1  58 aekalkklleslleLreelleqne.ikkla...eskeeeekkkskrkrkkkkkeetslee......lwkeleklekalkpf 128
                  +k +kkl ++l +Lr+   ++n+  ++ +   e++ee e++++++++++++ +     +      ++ +l+kl+++++p 
  EEA22996.1  50 DQKRIKKLQSELADLRHYKKATNPgAQD-EeegEEEEEGEEEEEEEEEEEEEGD-----DgsddriIEVKLQKLKDTYDPA 124
                 3566677777777777777566664433.2344222222222222222223333.....2334454455999999998886 PP

  == domain 2  score: 2.1 bits;  conditional E-value: 0.18
   AATF-Che1  49 eefeealeeaekalkklleslleLreelleqne..ikkla.....................e 87 
                 + +++ ++++ k++ +l++ + +Lr +  + ++      +                      
  EEA22996.1 145 QRLKDSYNDLYKETAALVKIMSSLRAQV-KHHKrrA---EqwqrwcaglsaqnmappiaqvV 202
                 4577889999999999999999999999.3333222...12345555555555555555441 PP

  == domain 3  score: -1.1 bits;  conditional E-value: 1.7
   AATF-Che1  89 keeeekkkskrkrkkkkkeetsleelwkele 119
                 k++ +++++krk + + +++t++ee w+++ 
  EEA22996.1 470 KATGKRAAAKRKFQLETNANTNSEEDWEAIV 500
                 3445677788888888888888888888775 PP

>> DUF3450  Protein of unknown function (DUF3450)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   6.4    0.0028       4.5      11      78 ..      12      79 ..       3      98 .. 0.81
   2 ?    2.5   0.1     0.046        76      33      73 ..     145     185 ..     138     205 .. 0.51

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0028
     DUF3450 11 sgalaatldqalkeaekavaaaaqsqkkidklddekqellaeyralkeeleslevyneqlerlvasqe 78
                s  l+++ +++ k+  + +  a++ qkki  l+ ++   ++++++l++el++l+ y++  +   ++ e
  EEA22996.1 12 SKDLDTARNEVAKQDVQHQYDAERLQKKIRTLEGQRGCDQKRIKKLQSELADLRHYKKATNPGAQDEE 79
                555567778888999999999***********************************998766555555 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.046
     DUF3450  33 aqsqkkidklddekqellaeyralkeeleslevyneqlerl 73 
                 ++    +++l +e++ l++ + +l+++++  +   eq +r+
  EEA22996.1 145 QRLKDSYNDLYKETAALVKIMSSLRAQVKHHKRRAEQWQRW 185
                 23333344444444444444444444444444444444443 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.1  15.2     0.013        20     642     673 ..      76     106 ..      51     125 .. 0.46

  Alignments for each domain:
  == domain 1  score: 3.1 bits;  conditional E-value: 0.013
  DNA_pol_phi 642 dedeeddeeeeeeddeededseedddeeesde 673
                  +++ee +eeee+e++ee+e +ee+++ +++++
   EEA22996.1  76 QDEEEGEEEEEGEEEEEEE-EEEEEEGDDGSD 106
                  1111111111111111111.111111111111 PP

>> NOA36  NOA36 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6  13.0     0.011        17     255     303 ..      63     105 ..      16     111 .. 0.52

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.011
       NOA36 255 dydaylkalasgddeddegdedddddddeedddeeed.dedeeeeeeees 303
                 d   y       ++ ++ g++d+++ ++ee+ +eee+ +e+eeee ++ s
  EEA22996.1  63 DLRHY-------KKATNPGAQDEEEGEEEEEGEEEEEeEEEEEEEGDDGS 105
                 33333.......34444555555444443333333220223333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (674 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1817  (0.101344); expected 358.6 (0.02)
Passed bias filter:                      901  (0.0502538); expected 358.6 (0.02)
Passed Vit filter:                       146  (0.00814323); expected 17.9 (0.001)
Passed Fwd filter:                        27  (0.00150594); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.98u 0.33s 00:00:01.31 Elapsed: 00:00:00.53
# Mc/sec: 3850.13
//
Query:       EEA22997.1  [L=389]
Description: peroxisomal membrane protein pex16 (peroxin-16) [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.2e-140  468.3   0.0   1.4e-140  468.1   0.0    1.0  1  Pex16     Peroxisomal membrane protein (Pex16)


Domain annotation for each model (and alignments):
>> Pex16  Peroxisomal membrane protein (Pex16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  468.1   0.0  7.6e-145  1.4e-140       2     324 .]      24     381 ..      23     381 .. 0.98

  Alignments for each domain:
  == domain 1  score: 468.1 bits;  conditional E-value: 7.6e-145
       Pex16   2 aYekfvlknasqvsqiEstlrsltyilpgrfrdaeiasEalysllnLlslyhDslLeravks........ppseharytrawtkksklyrrvalvLqvv 92 
                 +Ye+fv+kn+++v+q+Es+lrsltyi+pgrfr++e+ sE+++s+++LlslyhDsl++r++++         ps+haryt++w +ks+lyr++a++Lq++
  EEA22997.1  24 SYENFVTKNVNTVNQVESALRSLTYIIPGRFRESELPSECVHSGVQLLSLYHDSLVSRVISQlpstiprpIPSPHARYTKYWISKSPLYRKLAVALQII 122
                 7*********************************************************99889*******89*************************** PP

       Pex16  93 eytelllEmaakrklGekgrWrvvvlieaiKavlRllLlrltksrpllspplperevdpeeleeeee.....................kkewtlkrtgr 170
                 +ytell+Em+a+r+ Gek rWrv+++ie+ Kav+RllLlrlt+srpl+spplpere+dp++ e+e+e                     + +wt++rtg+
  EEA22997.1 123 QYTELLWEMTARRR-GEKVRWRVIAIIEFAKAVCRLLLLRLTNSRPLVSPPLPERETDPRAAEAEKEaaagdwngmdepieepsvsssDLSWTMPRTGL 220
                 **************.**************************************************99*********************9********** PP

       Pex16 171 vlpslassgdissyllskvltaddikpptkllrrlkgsaqlAEvlyilrPlvyvlalrrygrr..swkPwllslalellsrqlrk...lrt...kkkks 261
                 +lpsl++ ++issyl+skvltadd+k+p +ll+r++g++q+AE+lyilrP++y+la++r++++  sw+Pwl+++ le+ srql+k     +   +  + 
  EEA22997.1 221 TLPSLPDASEISSYLISKVLTADDVKAPASLLHRVSGQGQFAEILYILRPVIYALAMQRWSKNkrSWSPWLIGFGLEYGSRQLAKrdlA-EraaGGLRG 318
                 ************************************************************99999********************7752.25678899* PP

       Pex16 262 lsalereelsrRklallwyllRgpfyekvtkpkleglakrlesvpllglvgglledylplwde 324
                 l+ ler+el++R++a++w+++Rg+fye++tkp+l gla++l+++pll++vggll+dy++lwd+
  EEA22997.1 319 LTGLERDELKKRGWAMGWWMMRGAFYENITKPWLGGLADKLKGKPLLDIVGGLLDDYEYLWDN 381
                 **************************************************************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (389 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       386  (0.0215294); expected 358.6 (0.02)
Passed bias filter:                      345  (0.0192426); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.55u 0.28s 00:00:00.83 Elapsed: 00:00:00.46
# Mc/sec: 2518.54
//
Query:       EEA22998.1  [L=389]
Description: peroxisomal membrane protein pex16 (peroxin-16) [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.2e-140  468.3   0.0   1.4e-140  468.1   0.0    1.0  1  Pex16     Peroxisomal membrane protein (Pex16)


Domain annotation for each model (and alignments):
>> Pex16  Peroxisomal membrane protein (Pex16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  468.1   0.0  7.6e-145  1.4e-140       2     324 .]      24     381 ..      23     381 .. 0.98

  Alignments for each domain:
  == domain 1  score: 468.1 bits;  conditional E-value: 7.6e-145
       Pex16   2 aYekfvlknasqvsqiEstlrsltyilpgrfrdaeiasEalysllnLlslyhDslLeravks........ppseharytrawtkksklyrrvalvLqvv 92 
                 +Ye+fv+kn+++v+q+Es+lrsltyi+pgrfr++e+ sE+++s+++LlslyhDsl++r++++         ps+haryt++w +ks+lyr++a++Lq++
  EEA22998.1  24 SYENFVTKNVNTVNQVESALRSLTYIIPGRFRESELPSECVHSGVQLLSLYHDSLVSRVISQlpstiprpIPSPHARYTKYWISKSPLYRKLAVALQII 122
                 7*********************************************************99889*******89*************************** PP

       Pex16  93 eytelllEmaakrklGekgrWrvvvlieaiKavlRllLlrltksrpllspplperevdpeeleeeee.....................kkewtlkrtgr 170
                 +ytell+Em+a+r+ Gek rWrv+++ie+ Kav+RllLlrlt+srpl+spplpere+dp++ e+e+e                     + +wt++rtg+
  EEA22998.1 123 QYTELLWEMTARRR-GEKVRWRVIAIIEFAKAVCRLLLLRLTNSRPLVSPPLPERETDPRAAEAEKEaaagdwngmdepieepsvsssDLSWTMPRTGL 220
                 **************.**************************************************99*********************9********** PP

       Pex16 171 vlpslassgdissyllskvltaddikpptkllrrlkgsaqlAEvlyilrPlvyvlalrrygrr..swkPwllslalellsrqlrk...lrt...kkkks 261
                 +lpsl++ ++issyl+skvltadd+k+p +ll+r++g++q+AE+lyilrP++y+la++r++++  sw+Pwl+++ le+ srql+k     +   +  + 
  EEA22998.1 221 TLPSLPDASEISSYLISKVLTADDVKAPASLLHRVSGQGQFAEILYILRPVIYALAMQRWSKNkrSWSPWLIGFGLEYGSRQLAKrdlA-EraaGGLRG 318
                 ************************************************************99999********************7752.25678899* PP

       Pex16 262 lsalereelsrRklallwyllRgpfyekvtkpkleglakrlesvpllglvgglledylplwde 324
                 l+ ler+el++R++a++w+++Rg+fye++tkp+l gla++l+++pll++vggll+dy++lwd+
  EEA22998.1 319 LTGLERDELKKRGWAMGWWMMRGAFYENITKPWLGGLADKLKGKPLLDIVGGLLDDYEYLWDN 381
                 **************************************************************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (389 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       386  (0.0215294); expected 358.6 (0.02)
Passed bias filter:                      345  (0.0192426); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 2671.04
//
Query:       EEA22999.1  [L=408]
Description: peroxisomal membrane protein pex16 (peroxin-16) [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   1.5e-137  458.1   0.0   5.9e-125  416.7   0.0    2.0  2  Pex16     Peroxisomal membrane protein (Pex16)


Domain annotation for each model (and alignments):
>> Pex16  Peroxisomal membrane protein (Pex16)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.3   0.1   1.1e-14     2e-10       2      39 ..      24      61 ..      23      67 .. 0.90
   2 !  416.7   0.0  3.3e-129  5.9e-125      23     324 .]      64     400 ..      56     400 .. 0.97

  Alignments for each domain:
  == domain 1  score: 40.3 bits;  conditional E-value: 1.1e-14
       Pex16  2 aYekfvlknasqvsqiEstlrsltyilpgrfrdaeias 39
                +Ye+fv+kn+++v+q+Es+lrsltyi+pgr+  +  +s
  EEA22999.1 24 SYENFVTKNVNTVNQVESALRSLTYIIPGRLPTSMSMS 61
                7*****************************98887666 PP

  == domain 2  score: 416.7 bits;  conditional E-value: 3.3e-129
       Pex16  23 sltyilpgrfrdaeiasEalysllnLlslyhDslLeravks........ppseharytrawtkksklyrrvalvLqvveytelllEmaakrklGekgrW 113
                  lt  ++grfr++e+ sE+++s+++LlslyhDsl++r++++         ps+haryt++w +ks+lyr++a++Lq+++ytell+Em+a+r+ Gek rW
  EEA22999.1  64 GLTIDIAGRFRESELPSECVHSGVQLLSLYHDSLVSRVISQlpstiprpIPSPHARYTKYWISKSPLYRKLAVALQIIQYTELLWEMTARRR-GEKVRW 161
                 567779*******************************99889*******89*****************************************.****** PP

       Pex16 114 rvvvlieaiKavlRllLlrltksrpllspplperevdpeeleeeee.....................kkewtlkrtgrvlpslassgdissyllskvlt 191
                 rv+++ie+ Kav+RllLlrlt+srpl+spplpere+dp++ e+e+e                     + +wt++rtg++lpsl++ ++issyl+skvlt
  EEA22999.1 162 RVIAIIEFAKAVCRLLLLRLTNSRPLVSPPLPERETDPRAAEAEKEaaagdwngmdepieepsvsssDLSWTMPRTGLTLPSLPDASEISSYLISKVLT 260
                 ********************************************99*********************9******************************* PP

       Pex16 192 addikpptkllrrlkgsaqlAEvlyilrPlvyvlalrrygrr..swkPwllslalellsrqlrk...lrt...kkkkslsalereelsrRklallwyll 282
                 add+k+p +ll+r++g++q+AE+lyilrP++y+la++r++++  sw+Pwl+++ le+ srql+k     +   +  + l+ ler+el++R++a++w+++
  EEA22999.1 261 ADDVKAPASLLHRVSGQGQFAEILYILRPVIYALAMQRWSKNkrSWSPWLIGFGLEYGSRQLAKrdlA-EraaGGLRGLTGLERDELKKRGWAMGWWMM 358
                 ***************************************99999********************7752.25678899********************** PP

       Pex16 283 Rgpfyekvtkpkleglakrlesvpllglvgglledylplwde 324
                 Rg+fye++tkp+l gla++l+++pll++vggll+dy++lwd+
  EEA22999.1 359 RGAFYENITKPWLGGLADKLKGKPLLDIVGGLLDDYEYLWDN 400
                 *****************************************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (408 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       404  (0.0225333); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.52u 0.24s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 2924.10
//
Query:       EEA23000.1  [L=368]
Description: ribonuclease HI large subunit [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    7.9e-48  162.9   0.0    8.8e-43  146.5   0.0    2.1  2  RNase_HII  Ribonuclease HII


Domain annotation for each model (and alignments):
>> RNase_HII  Ribonuclease HII
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  146.5   0.0   4.9e-47   8.8e-43       1     159 [.      73     248 ..      73     267 .. 0.92
   2 !   14.7   0.0   1.1e-06      0.02     158     197 ..     273     313 ..     260     314 .. 0.79

  Alignments for each domain:
  == domain 1  score: 146.5 bits;  conditional E-value: 4.9e-47
                 EEEEEE-TT-SBS-EEEEEEEECGHHHH..HHHCTTGTTGTTS-HHHHHHHHHHHH..............SEEEEEEE-HHHHH.HHTTTS-HHHHHHH CS
   RNase_HII   1 iGiDEaGrGpvlGplvvaavavekeree..elkklgvkDSKkLskqkreeLaklik..............kkiekrklvaeeikyaseneinlneikaa 83 
                 +G+DEaGrGpvlGp+v+ a++++k+ e    ++++ ++DSK L++  r+ L + i+              k  ++r+++a++++  s+  +nln ++ +
  EEA23000.1  73 LGVDEAGRGPVLGPMVYSAFYLPKHLERplLTEEYSFDDSKVLTPVVRARLMQSICtpgaslhdscgwavKLLSARDISAGMMR-PSTGVYNLNAQAMD 170
                 6***********************9887657789***********************************999*********999.99************ PP

                 HHHHHHH.HHHHTCEECCECCCE--SSHHHHHHHHHHHHC.CEEEEETTGGGT-HHHHHHHHHHHHHHHHHHHHHHHH CS
   RNase_HII  84 ltlavik.lleklgvkvdeilvdgvttpeslkkkleqiik.ikvtvekkadekyllvaaASiiAkverdeelellkrk 159
                 +t+++i+  l+++ ++v+e+++d++++p+ ++ kl+  ++ + +tv+kkad++y++v+aAS++Akv+rd+ le+  ++
  EEA23000.1 171 ATIEIIRgVLNEKHINVTEVYIDTIGNPATYQAKLQRLFPtLSITVAKKADSLYPCVSAASVVAKVTRDVALESCYQA 248
                 *******777778****************************9***************************999975443 PP

  == domain 2  score: 14.7 bits;  conditional E-value: 1.1e-06
                 HHCSH.--TTSSTTSHHHHHHHHHHHHH..S--TTB-TTSHH CS
   RNase_HII 158 rkpgtldkgsGyasdektrallkkgats..klpdivrlsfkt 197
                 +k +   +gsGy+sd k  ++l+++++s     +  r+s+ t
  EEA23000.1 273 KK-EAAGWGSGYPSDSKCVNWLRQNMDSvfGWGNECRFSWGT 313
                 33.3578*********************99777788999976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (368 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       350  (0.0195214); expected 358.6 (0.02)
Passed bias filter:                      314  (0.0175135); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.49u 0.23s 00:00:00.72 Elapsed: 00:00:00.40
# Mc/sec: 2738.44
//
Query:       EEA23001.1  [L=637]
Description: Cupin domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.6e-35  120.0   0.8    6.2e-35  119.3   0.8    1.4  1  CENP-C_C  Mif2/CENP-C like
      7e-33  114.2   6.8      7e-33  114.2   6.8    3.3  3  Mif2_N    Kinetochore CENP-C fungal homologue, Mif2, N-termin
    6.4e-06   25.8   0.0    1.3e-05   24.8   0.0    1.5  1  Cupin_2   Cupin domain


Domain annotation for each model (and alignments):
>> CENP-C_C  Mif2/CENP-C like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.3   0.8     1e-38   6.2e-35       1      85 []     491     575 ..     491     575 .. 0.99

  Alignments for each domain:
  == domain 1  score: 119.3 bits;  conditional E-value: 1e-38
                 -EEEEE--TTS-EEEEEEE-TCCCEEEEE--SEEEEEEEEESEEEEEETTEEEEEETT-EEEE-TT-EEEEEE-SSS-EEEEEEE CS
    CENP-C_C   1 fklaklldkkflasGilkLppgaeKkkknskkatlvFyViqGrvevtvsktsfvigkgsvFqvPagneysieNklnkeaklfFvq 85 
                 f++akll+++f++sGi++Lp++++Kk+knsk++++vFyV+ Grv+v++++ +f++gkg++FqvP+gn+ys++N++ kea+lfF+q
  EEA23001.1 491 FRVAKLLSQPFFGSGIVELPAKGVKKPKNSKRMHMVFYVCFGRVQVDINGVQFTAGKGCIFQVPRGNHYSFANITPKEARLFFTQ 575
                 89**********************************************************************************9 PP

>> Mif2_N  Kinetochore CENP-C fungal homologue, Mif2, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  114.2   6.8   1.2e-36     7e-33       1     126 [.      14     135 ..      14     152 .. 0.89
   2 ?    2.9   6.1     0.028   1.6e+02      46     124 ..     230     309 ..     186     327 .. 0.54
   3 ?    0.2   0.8      0.19   1.1e+03      36      66 ..     409     441 ..     403     480 .. 0.56

  Alignments for each domain:
  == domain 1  score: 114.2 bits;  conditional E-value: 1.2e-36
      Mif2_N   1 ysnvGkaGRkTGvtlkdtgvrDehGlepidglFSsPeksekengeeeeeeededesgeedmdleessgpepadllsgrr..essrlplprarSPaktsl 97 
                 ysnvGk+GR+TG+tlk+ g+rDehG+e++dg+FSsPeks        + + +e+  g+e m+++e  gp+p+d+ls+ +  +s+ +p+p +rSP k+ l
  EEA23001.1  14 YSNVGKQGRRTGITLKE-GRRDEHGMEELDGVFSSPEKS------PVRFNGNETMMGSEGMSIDEDDGPGPTDFLSRSAarRSPFFPPPASRSPRKSGL 105
                 89***************.*********************......33445678899********************99888999*************** PP

      Mif2_N  98 ksparrnssla.resqeerpsssPsraasq 126
                 ++++rr++ l+ ++ ++++ +ssP++a+++
  EEA23001.1 106 GGSPRRTPGLRsSPIAQNDVPSSPTSARQR 135
                 ***********655677788999*998764 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.028
      Mif2_N  46 eeeeeededesge.....edmdleessgpepadllsgrressrlpl.prarSPaktslksparrnsslaresqeerpsssPsraa 124
                 ++ + +++d+s++     ++ +l +++ + pa++  +       p+    +SP k +  + + ++++ +  +qe++ +  P+++a
  EEA23001.1 230 DTTNVQNDDRSEDepspiQSASLRTKKRKAPATTNDDVD----TPVeDIPHSPPKKKRAGRPPKSQAQK-ATQEKTDEARPAKKA 309
                 222222223333300001333333333333333333333....33312336666655555555555555.566666777777654 PP

  == domain 3  score: 0.2 bits;  conditional E-value: 0.19
      Mif2_N  36 Peks..ekengeeeeeeededesgeedmdlees 66 
                 Pek+  +k++g++++++++++ ++++d d++e 
  EEA23001.1 409 PEKKggKKRKGSSKKSKSKKQGDSDSDDDTDER 441
                 666655333333333333333333344444433 PP

>> Cupin_2  Cupin domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.8   0.0   2.2e-09   1.3e-05       2      68 ..     506     572 ..     505     574 .. 0.86

  Alignments for each domain:
  == domain 1  score: 24.8 bits;  conditional E-value: 2.2e-09
                 EEEEETTE.EEEEECSSSEEEEEEEEESEEEEEECTEEEEEETTEEEEE-TT-EEEEEE-SSS-EEEE CS
     Cupin_2   2 lvelppGe.sapshrHpgedeffyVleGegeltvdgeeveleaGdsvyfpagtpHrfrNtgdeparll 68 
                 +velp  + + p  + + +  +fyV  G++ + ++g +++ ++G+++ +p+g    f+N + ++arl+
  EEA23001.1 506 IVELPAKGvKKPKNSKRMH-MVFYVCFGRVQVDINGVQFTAGKGCIFQVPRGNHYSFANITPKEARLF 572
                 6778888845555555666.99*******************************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (637 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       922  (0.0514251); expected 358.6 (0.02)
Passed bias filter:                      384  (0.0214178); expected 358.6 (0.02)
Passed Vit filter:                        44  (0.00245412); expected 17.9 (0.001)
Passed Fwd filter:                        13  (0.000725082); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.71u 0.33s 00:00:01.04 Elapsed: 00:00:00.56
# Mc/sec: 3422.42
//
Query:       EEA23002.1  [L=378]
Description: dimeric dihydrodiol dehydrogenase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.2e-18   66.0   0.0    8.1e-18   65.4   0.0    1.3  1  GFO_IDH_MocA   Oxidoreductase family, NAD-binding Rossmann fo
    0.00018   22.1   0.0     0.0003   21.4   0.0    1.3  1  NAD_binding_3  Homoserine dehydrogenase, NAD binding domain


Domain annotation for each model (and alignments):
>> GFO_IDH_MocA  Oxidoreductase family, NAD-binding Rossmann fold
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   65.4   0.0     9e-22   8.1e-18       2     117 ..       6     133 ..       5     136 .. 0.86

  Alignments for each domain:
  == domain 1  score: 65.4 bits;  conditional E-value: 9e-22
                   EEEEETTSHHHHHHHHHHHHTTTTE.......EEEEEEC.SSHHHHHHHHHHTTHE....EESSHHHHHTCTTESEEEE-S-GGGHHHHHHHHHHTT CS
  GFO_IDH_MocA   2 rvaiiGaGkigskhlrplnesqrle.......evvalld.pdaeraeavaesfgve....aysdleelladpeidavivatpngtheelakaaleag 86 
                   r++i  +G i++ +++ l +  +          v+a+ + ++a+ra+++  ++ ++    ay +++el++dp++d+++vatp ++h++ a+ aleag
    EEA23002.1   6 RWGILATGGIAKTFVKDLLKDPSARdasdithTVTAVASsSSASRAQQFITELSIPgnpkAYGSYDELVNDPNVDVIYVATPHSHHYQNARLALEAG 102
                   566777777777777777776444467778877777765156789***********99*************************************** PP

                   -EEEEESSS-SSHHHHHHHHHHHHHHTS-EE CS
  GFO_IDH_MocA  87 khvllEKPlattveeakelvelaekkgklvs 117
                   khvl+EK ++ + ++ k lv+la++kg  ++
    EEA23002.1 103 KHVLCEKAFTVNAAQTKILVDLARSKGLFLM 133
                   **************************98765 PP

>> NAD_binding_3  Homoserine dehydrogenase, NAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.4   0.0   3.4e-08    0.0003       3     111 ..      13     129 ..      12     134 .. 0.89

  Alignments for each domain:
  == domain 1  score: 21.4 bits;  conditional E-value: 3.4e-08
                    SHHHHHHHHHHHH---S.....SEEEEEEEEESSEEE-TT....HHHHHT--CB---HHHHHHHHS-EEEEE-S--HHHHTTHHHHHHTTEEEE-S CS
  NAD_binding_3   3 GaiGsavleqlkrqqse.....ielelvavadrdsllskd....rkallasealtldlddliahldpdvvVEcasseavaelvlkaLkagkdvvta 89 
                    G+i++++++ l++++s      i+ ++ ava ++s+ +++     ++  ++ + + + d+l++++++dv+  +++++   + +  aL+agk+v+  
     EEA23002.1  13 GGIAKTFVKDLLKDPSArdasdITHTVTAVASSSSASRAQqfitELSIPGNPKAYGSYDELVNDPNVDVIYVATPHSHHYQNARLALEAGKHVLC- 107
                    99**********9999999*9*************55555579987788889999****************999*******************986. PP

                    --CGGG.-HHHHHHHTSSSTTS- CS
  NAD_binding_3  90 nkgala.dealyeeLreaaeang 111
                      +a++ + a+++ L+++a+++g
     EEA23002.1 108 -EKAFTvNAAQTKILVDLARSKG 129
                    .5677769999999999999987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (378 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       394  (0.0219756); expected 358.6 (0.02)
Passed bias filter:                      363  (0.0202465); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.50u 0.28s 00:00:00.78 Elapsed: 00:00:00.44
# Mc/sec: 2607.33
//
Query:       EEA23003.1  [L=272]
Description: adenylate kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.5e-59  200.4   0.0    1.9e-59  200.1   0.0    1.1  1  ADK              Adenylate kinase
    8.4e-23   81.3   0.0    1.4e-22   80.5   0.0    1.4  1  AAA_17           AAA domain
    9.9e-18   63.8   0.0    2.6e-17   62.5   0.0    1.8  2  ADK_lid          Adenylate kinase, active site lid
    5.7e-07   30.1   0.0    8.6e-07   29.6   0.0    1.3  1  AAA_18           AAA domain
    6.8e-06   26.3   0.0    1.2e-05   25.5   0.0    1.4  1  AAA_33           AAA domain
  ------ inclusion threshold ------
      0.071   13.3   0.0       0.11   12.7   0.0    1.4  1  AAA_28           AAA domain
      0.086   12.2   0.0       0.15   11.4   0.0    1.3  1  Mg_chelatase     Magnesium chelatase, subunit ChlI
       0.11   12.1   0.0       0.35   10.5   0.0    1.8  2  Thymidylate_kin  Thymidylate kinase
       0.14   12.5   0.1       0.37   11.2   0.1    1.7  1  TSC22            TSC-22/dip/bun family


Domain annotation for each model (and alignments):
>> ADK  Adenylate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  200.1   0.0   9.7e-63   1.9e-59       1     150 [.      50     236 ..      50     237 .. 0.99

  Alignments for each domain:
  == domain 1  score: 200.1 bits;  conditional E-value: 9.7e-63
                 EEESTTSSHHHHHHHHHHHHTSEEEEHHHHHHHHHHCT-HHHHHHHHHHHTTSS--HHHHHHHHHHHHHCH.GTTTEEEEESB-SSHHHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         ADK   1 llGaPgaGKGtqaeklvkkyglahlstGdllRaevksgtelGkeakevmdkgelvpdevvvklvkeeleke.dkkkgfllDGfPRtveqaealeellee 98 
                 l+G+PgaGKGtqa++l++ky+++hl+tGd+lR++v+++t+lGkeak++md+g lv+de++v+++k+ele++ ++k+gf+lDGfPRtv+qae+l+++l+ 
  EEA23003.1  50 LIGPPGAGKGTQAPRLKEKYCVCHLATGDMLRSQVAKKTPLGKEAKKIMDQGGLVSDEIMVNMIKSELETNsECKNGFILDGFPRTVAQAERLDDMLSA 148
                 79*******************************************************************999*************************** PP

                 HTSEESEEEEEE--HHHHHHHHHT....................................GSHHHHHHHHHHHHHHHHHHHHHHHHTT CS
                 xxxxxxxxxxxxxxxxxxxxxxxx....................................xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         ADK  99 ekvkldlvleldvpeevlveRltg....................................DneetvkkRletykkqtkplidyykkkg 150
                 ++ kl+  +el++++++lv R+tg                                    Dn+ t++kRl+ty++qt+p++dyykk+g
  EEA23003.1 149 RNEKLQHAVELQIDDALLVARITGrlvhpasgrsyhkifnppkqdmkdditgepliqrsdDNAATLEKRLATYHAQTSPVVDYYKKTG 236
                 *************************************************************************************986 PP

>> AAA_17  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.5   0.0   7.2e-26   1.4e-22       1     129 [.      51     183 ..      51     187 .. 0.87

  Alignments for each domain:
  == domain 1  score: 80.5 bits;  conditional E-value: 7.2e-26
                 EE-TTSSHHHHHHHHHHHHTEEEEEHHHHHHHHHHTTT.S.HSSHHHHCTSHHHHHHHHHHHHHHHHHHHH.HSSEEEEEE-SEEEETTEEEESSHHHH CS
      AAA_17   1 lGgPGsGKgtqceklvekygfthlsaGdllreeakrgg.l.akardemrklpleekkelqkeaaekiaeea.kkkgvlvdghprikeqagfldglpkev 96 
                 +G+PG+GKgtq+ +l+eky + hl +Gd+lr+ ++++  l ++a++ m+++ l+ ++ +  +++ +++ ++ +k+g+++dg+pr+ +qa+ ld++ +  
  EEA23003.1  51 IGPPGAGKGTQAPRLKEKYCVCHLATGDMLRSQVAKKTpLgKEAKKIMDQGGLVSDEIMVNMIKSELETNSeCKNGFILDGFPRTVAQAERLDDMLSAR 149
                 69*****************************77766652656677777799****************999889999*********************98 PP

                 HHHH..SEEEEEE--HHHHHHHHHHH...TTST-TS CS
      AAA_17  97 leelkpdaiilleadpeeilerrlkd...rtrgrdd 129
                  e+l  ++ + l++d+  +++r   +     +gr++
  EEA23003.1 150 NEKL--QHAVELQIDDALLVARITGRlvhPASGRSY 183
                 8888..999999999999999987775423577765 PP

>> ADK_lid  Adenylate kinase, active site lid
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.5   0.0   1.3e-20   2.6e-17       1      36 []     173     208 ..     173     208 .. 0.98
   2 ?   -2.9   0.0       3.6   7.2e+03       9      15 ..     219     225 ..     219     230 .. 0.65

  Alignments for each domain:
  == domain 1  score: 62.5 bits;  conditional E-value: 1.3e-20
                 EEE-TTT--EEETTTB--SSTTB-TTT--.-B--GG CS
     ADK_lid   1 RrvCpkCGrsYhvvfnpPkveglCDkCGepLvqRsD 36 
                 R+v+p++GrsYh +fnpPk+++++D +GepL+qRsD
  EEA23003.1 173 RLVHPASGRSYHKIFNPPKQDMKDDITGEPLIQRSD 208
                 9***********999********************9 PP

  == domain 2  score: -2.9 bits;  conditional E-value: 3.6
                 -EEETTT CS
     ADK_lid   9 rsYhvvf 15 
                 ++Yh ++
  EEA23003.1 219 ATYHAQT 225
                 69**544 PP

>> AAA_18  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.6   0.0   4.3e-10   8.6e-07       1     119 [.      48     179 ..      48     188 .. 0.80

  Alignments for each domain:
  == domain 1  score: 29.6 bits;  conditional E-value: 4.3e-10
      AAA_18   1 IlltGtpGvGKttlakeLskrlgf......gvnlrdvakenglllevdpe.aldeskrldedkldklldaleenssaleegknlvidghlaeleseaak 92 
                 I+l G+pG+GK t a +L+++  +      g+ lr+ ++++ +l  + ++ + +  ++ de +++ + ++le ns   e  +  ++dg++    ++++ 
  EEA23003.1  48 IILIGPPGAGKGTQAPRLKEKY-CvchlatGDMLRSQVAKKTPLGKEAKKiMDQGGLVSDEIMVNMIKSELETNS---ECKNGFILDGFPRTVAQAERL 142
                 9*****************9994.3568888888888888888888888886555566666666666666666664...445566*******99988888 PP

      AAA_18  93 dikk..........vvLtaspeelleRlekRgyeeak 119
                 d             v L+ ++  l  R+  R  ++a 
  EEA23003.1 143 DDMLsarneklqhaVELQIDDALLVARITGRLVHPAS 179
                 87778**************************988766 PP

>> AAA_33  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.5   0.0   6.2e-09   1.2e-05       2     118 ..      48     173 ..      48     185 .. 0.76

  Alignments for each domain:
  == domain 1  score: 25.5 bits;  conditional E-value: 6.2e-09
      AAA_33   2 vllvGlpGsGKstlaerllkklgavllssdtlrr.rlfg.....tdqqsktdytr.vldr.lyqilnelarkalsagrnvildatnlsrrerarflkla 92 
                 ++l+G+pG+GK t a rl +k  +++l++ +++r ++++     ++ +++ d+   v+d+ + ++++  ++ + + ++++ild   ++ ++ +r++ ++
  EEA23003.1  48 IILIGPPGAGKGTQAPRLKEKYCVCHLATGDMLRsQVAKktplgKEAKKIMDQGGlVSDEiMVNMIKSELETNSECKNGFILDGFPRTVAQAERLDDML 146
                 699******************9999998877666366666554433333334444233336677888888888888899***99999999999999998 PP

      AAA_33  93 rrlgvp.vrivvvetdeetlkeRlakR 118
                 +  + +  ++v ++ d+++l +R+  R
  EEA23003.1 147 SARNEKlQHAVELQIDDALLVARITGR 173
                 8555442689**************999 PP

>> AAA_28  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   0.0   5.7e-05      0.11       1      80 [.      47     131 ..      47     182 .. 0.65

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 5.7e-05
      AAA_28   1 kivitGgestGKTtlleaLaargypvv...pEaareileeklakgedalpwv.edllafaervleeqleeeaaa..aankvlfcDr 80 
                 +i+++G++++GK t + +L+++  +++    ++ r  + +k+  g++ +++  ++   + ++++ + ++ e ++  + ++ +++D 
  EEA23003.1  47 RIILIGPPGAGKGTQAPRLKEKYCVCHlatGDMLRSQVAKKTPLGKE-AKKImDQGGLVSDEIMVNMIKSELETnsECKNGFILDG 131
                 79*******************98887755566666666666644444.33333455555555555555555555445566677765 PP

>> Mg_chelatase  Magnesium chelatase, subunit ChlI
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0   7.4e-05      0.15      20      44 ..      43      67 ..      38     102 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 7.4e-05
  Mg_chelatase 20 aGgHnlllvGppGsGKtmlakrlps 44
                  a +  ++l+GppG+GK   a rl++
    EEA23003.1 43 AEQFRIILIGPPGAGKGTQAPRLKE 67
                  556789****************975 PP

>> Thymidylate_kin  Thymidylate kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00018      0.35       3      61 ..      52     113 ..      52     124 .. 0.87
   2 ?   -2.5   0.0       1.8   3.5e+03     146     181 ..     215     250 ..     197     253 .. 0.58

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00018
                      ESTTSSHHHHHHHHHHHHHHTTE....EEEESSSTTSHHHHHHHHHHHTCS---HHHHHHHH CS
  Thymidylate_kin   3 GlDGaGKttqaellkerlkeegik...vvltrepggteiGekirelllkeeeleeqteallf 61 
                      G  GaGK tqa  lke+++  +++   +++++  ++t++G+ +++++ +   ++++ +++++
       EEA23003.1  52 GPPGAGKGTQAPRLKEKYCVCHLAtgdMLRSQVAKKTPLGKEAKKIMDQGGLVSDEIMVNMI 113
                      5669*************987776656899999**************9999999999988876 PP

  == domain 2  score: -2.5 bits;  conditional E-value: 1.8
                      HHHHHHHHHHHHHHHHHHHTTSTEEEEETTS-HHHH CS
  Thymidylate_kin 146 eeqldflrkvrerylelakederiliidasksieev 181
                      e++l +++  +    + +k+++ ++ idas++  +v
       EEA23003.1 215 EKRLATYHAQTSPVVDYYKKTGIWCGIDASQEPGQV 250
                      333333333333355556667788889999887666 PP

>> TSC22  TSC-22/dip/bun family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.1   0.00018      0.37      13      35 ..       6      28 ..       4      30 .. 0.93

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00018
       TSC22 13 rEeVevLkekIkeLeernselee 35
                +E+V+ Lk+ I  Le+r++ le+
  EEA23003.1  6 QETVDGLKDIIHKLESRVADLES 28
                79*****************9996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (272 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       485  (0.0270511); expected 358.6 (0.02)
Passed bias filter:                      453  (0.0252663); expected 358.6 (0.02)
Passed Vit filter:                        66  (0.00368119); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.50u 0.29s 00:00:00.79 Elapsed: 00:00:00.46
# Mc/sec: 1777.57
//
Query:       EEA23004.1  [L=353]
Description: 26S proteasome regulatory particle subunit Rpn8, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.2e-37  127.0   0.5    7.9e-37  126.1   0.5    1.5  1  MitMem_reg  Maintenance of mitochondrial structure and functi
      2e-30  105.2   0.0    4.6e-30  104.0   0.0    1.6  1  JAB         JAB1/Mov34/MPN/PAD-1 ubiquitin protease


Domain annotation for each model (and alignments):
>> MitMem_reg  Maintenance of mitochondrial structure and function
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  126.1   0.5   8.8e-41   7.9e-37       1     112 []     172     299 ..     172     299 .. 0.94

  Alignments for each domain:
  == domain 1  score: 126.1 bits;  conditional E-value: 8.8e-41
  MitMem_reg   1 Eaeeigvehllkpsiqdas.stlstglnrqyyslkilqerldlikdYlkkveegelpvnheilrnlqkllnllPhlet................eelek 82 
                 Eaeeigvehll+ +i+d + +tls++++ q++sl++l+ rl++i +Yl+kv + elpvnh+il nlq+++nllP+l+t                +el +
  EEA23004.1 172 EAEEIGVEHLLR-DIRDVAvGTLSNRITGQLQSLQGLHLRLRDIGQYLQKVLDHELPVNHAILGNLQDIFNLLPNLSTpksaneangtesdienSELVR 269
                 9***********.*****************************************************************777777777777766666999 PP

  MitMem_reg  83 efnvetnDvllvvyLasltrsilalnelle 112
                 +++v+tnD+l+ +yL+sl+r+i+a+++l+e
  EEA23004.1 270 AMSVKTNDQLMAIYLSSLIRAITAFHDLIE 299
                 9***************************86 PP

>> JAB  JAB1/Mov34/MPN/PAD-1 ubiquitin protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  104.0   0.0   5.2e-34   4.6e-30       4     118 .]      14     124 ..      12     124 .. 0.97

  Alignments for each domain:
  == domain 1  score: 104.0 bits;  conditional E-value: 5.2e-34
                 CEEEEEHHHHHHHHHHHHHHHHHT.S--EEEEEEEESSSEEEEEEEEEEESEEEESSECEEEEEHHHHHHHHHHHHHHHCTTSEEEEEEEESSSS-SS- CS
         JAB   4 qavhleslvllkildhalrtekee.eevmGlliGelnddttveitnvfalpfeetekdvdavsldqeylekksellkklrgrervvGWYhshpditvwl 101
                 ++v + +lvll+  dh+ rt+k + ++v+G+l+G+ ++  +v++ n+fa+pfee+ekd  +++ld++++e++++++kk+++re+++GWYhs+p++    
  EEA23004.1  14 RTVSVAPLVLLSAADHYGRTAKGTrKRVVGVLLGQNDGT-NVRVSNSFAVPFEEDEKDPTVWFLDHNFVESMNDMFKKINAREKLIGWYHSGPKL---- 107
                 79********************9989*********9999.*******************************************************.... PP

                 -HHHHHHHHHHHHHSTT CS
         JAB 102 sevdvrtqalyqrmdee 118
                 +++d+++++l++r++++
  EEA23004.1 108 RASDLEINELFKRYTPN 124
                 *************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (353 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1268  (0.0707234); expected 358.6 (0.02)
Passed bias filter:                      537  (0.0299515); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.56u 0.28s 00:00:00.84 Elapsed: 00:00:00.46
# Mc/sec: 2310.86
//
Query:       EEA23005.1  [L=232]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0025   17.5   1.7       0.19   11.4   0.2    2.4  2  SWIM      SWIM zinc finger


Domain annotation for each model (and alignments):
>> SWIM  SWIM zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.4   0.2   1.1e-05      0.19       1      22 [.     124     138 ..     116     144 .. 0.85
   2 !    5.1   0.1     0.001        18      27      34 ..     190     197 ..     183     203 .. 0.78

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 1.1e-05
        SWIM   1 yrVtlddervrlnkatCsCpef 22 
                 y+V l        +++CsCp+f
  EEA23005.1 124 YHVHLK-------TWNCSCPAF 138
                 677777.......*******99 PP

  == domain 2  score: 5.1 bits;  conditional E-value: 0.001
        SWIM  27 ipCkHalA 34 
                 ++CkH+lA
  EEA23005.1 190 PICKHMLA 197
                 79*****9 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (232 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      336  (0.0187406); expected 358.6 (0.02)
Passed Vit filter:                        17  (0.000948185); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.43u 0.27s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 1651.71
//
Query:       EEA23006.1  [L=336]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (336 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1972  (0.109989); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                        21  (0.00117129); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.80u 0.33s 00:00:01.13 Elapsed: 00:00:00.45
# Mc/sec: 2262.22
//
Query:       EEA23007.1  [L=454]
Description: monocarboxylate transporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.2e-25   90.3  73.3    9.3e-15   54.4  35.0    2.5  2  MFS_1     Major Facilitator Superfamily


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.3  38.8   5.9e-16   1.1e-11      12     241 ..      78     292 ..      61     299 .. 0.82
   2 !   54.4  35.0   5.2e-19   9.3e-15       1     167 [.     264     438 ..     264     451 .. 0.90

  Alignments for each domain:
  == domain 1  score: 44.3 bits;  conditional E-value: 5.9e-16
       MFS_1  12 rsilgpalpl.alaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllllfa.sslw.lllvlrvlqGlgagalfpaga 107
                  +  + ++   ++ +  g s+s++ ++ +l +   ++++++ +r++ ++G     llg+ lf++g +++ f+  ++  l++   +++Glg+++lf ++ 
  EEA23007.1  78 TTYCWGVFQAaLVEQGVG-SASTLAFVGSLTTSCISFMAVLNARVVRKLGTQLSGLLGISLFGIGEVMAGFTtGNVVgLFMTIGLVMGLGTSLLFMVVS 175
                 222455555534444555.88888888888888889999999***********************7777787688888********************* PP

       MFS_1 108 aliadwfpkeergraigllsagfslGailgpllggllasslgWravfyilaivsllafvlfllllpeepperkrkspkeeekgtgpaplvpawkallkd 206
                 +  a++f+  +rg a+g++ ag +lG ++   +   l+++lg  ++f +l++++l  ++   + ++ +++ + r+++           +v+ w++++  
  EEA23007.1 176 VTPAQYFKA-KRGIANGIVFAGGGLGGAIISFVTNGLLQALGIAWAFRVLGFITLATGLP--AAYLIKERVPIRPTS-----------FVE-WRLFRDY 259
                 ********9.***********************************************994..555555555555555...........555.******* PP

       MFS_1 207 pvlwillialllfffgfsglltllplylqevlgls 241
                 ++++ ++++ +l++f ++   ++lply    l+++
  EEA23007.1 260 RFIL-IFLGGALATFPLFVPPFFLPLY-TNSLNMT 292
                 *997.88888888889999********.7777776 PP

  == domain 2  score: 54.4 bits;  conditional E-value: 5.2e-19
       MFS_1   1 lllaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalglllll.fasslw.lllvlrvlqGl 97 
                 ++l+++l+++  ++  ++lp +++++l+++ps+   l++++ + +a++ l+ G+ sdr+G+  +++ +lll+al++l+l+ + ss+  +l+v+ ++ G+
  EEA23007.1 264 IFLGGALATFPLFVPPFFLP-LYTNSLNMTPSAGAGLVAAFNFSSAIGRLLCGFSSDRIGPLNTVFSSLLLSALSALVLWpV-SSSLgPLIVFVIVNGM 360
                 68999999999999999***.9***********9999**************************************7888844.67777*********** PP

       MFS_1  98 gagalfpagaaliadwfpkeergraigllsagfslGailgpllggllasslg........Wravfyilaivsllafvl 167
                 + g++f+++ +++  +f   + + a+g++ +g++ G++lg++++g+l+  +g        ++ + y ++ ++l ++ l
  EEA23007.1 361 ANGGFFATMPTVVGNVFGSARVSVAMGMVVTGWGGGYLLGAPIAGYLLNTGGgekggidaFHPAIYYAGSMALGSASL 438
                 ************************************************666679999999888888888888777554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (454 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       614  (0.0342462); expected 358.6 (0.02)
Passed bias filter:                      243  (0.0135535); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.39
# Mc/sec: 3453.75
//
Query:       EEA23008.1  [L=577]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    1.9e-19   70.0   0.0    9.7e-19   67.7   0.0    2.2  2  DDE_1          DDE superfamily endonuclease
      3e-15   56.0   0.2      9e-14   51.3   0.0    2.9  2  HTH_Tnp_Tc5    Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
      0.025   14.6   1.3       0.22   11.6   0.6    2.7  2  Med9           RNA polymerase II transcription mediator compl
      0.069   13.4   1.2       0.15   12.3   1.2    1.5  1  DUF1359        Protein of unknown function (DUF1359)
       0.07   12.7   0.0       0.23   11.1   0.0    1.9  1  HTH_24         Winged helix-turn-helix DNA-binding
      0.071   12.9   0.2       0.46   10.3   0.0    2.3  2  HTH_AsnC-type  AsnC-type helix-turn-helix domain


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.7   0.0   3.3e-22   9.7e-19       2     135 ..     203     337 ..     202     371 .. 0.84
   2 ?   -1.4   0.0      0.51   1.5e+03     119     168 ..     449     496 ..     446     505 .. 0.76

  Alignments for each domain:
  == domain 1  score: 67.7 bits;  conditional E-value: 3.3e-22
       DDE_1   2 erltvllcanaagsekLkplvigkaksprafkngektkkkldveyksnrkawltssifeeWLkvfdkrle..aekrkilLlldssrshetvel.lesel 97 
                 ++l+ +++ ++a+++k++p++i+ +k + ++++  k  k+ d+ +++++k+   ++i  eWL++fdk ++  a ++  lL +d++++h t e+ + +++
  EEA23008.1 203 RELVSTIEGISATGNKIPPMLIFTGKAILESWF--KYLKEEDWLITISDKGYSNDTIAYEWLQHFDKHTReqAGNNFRLLFMDNHDAHITSEFlSYCDK 299
                 5788999**************************..999********************************98889999***************99**** PP

       DDE_1  98 qniklvflPassasllqPldqgvvselKarYrrqllqa 135
                  +i ++ +P++++++lqPld   + + K+   r+++ +
  EEA23008.1 300 YKILAIAFPPHTTHILQPLDGLPFMQYKRIHGRAINDQ 337
                 *******************9877777666666555544 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.51
       DDE_1 119 gvvselKarYrrqllqalleeqnrlskeqkkltlldalkfikkAwnavsk 168
                 g+   lK+ +   l qa ++ q++ +   ++l+ l+a k  kk+  +v++
  EEA23008.1 449 GIRRRLKKIFDGSLTQAHIKDQQQAQI--ERLQTLNARKSAKKSKRQVQV 496
                 566678888888888888877776665..788889999999988888876 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.3   0.0     3e-17     9e-14       2      61 ..      64     123 ..      63     130 .. 0.93
   2 ?    1.2   0.1      0.12   3.7e+02      26      56 ..     229     265 ..     225     270 .. 0.68

  Alignments for each domain:
  == domain 1  score: 51.3 bits;  conditional E-value: 3e-17
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHTS CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRhg 61 
                  +++E+a++ W+++l+ rgip++ ++i+++A++++++ + + ++ ++++ +W++rF+kR+g
   EEA23008.1  64 DDQERAIILWMNDLDDRGIPPSVRMIKNYAEKVHQNMHPNADSLPQLGDRWVYRFLKRLG 123
                  79********************************88899999****************94 PP

  == domain 2  score: 1.2 bits;  conditional E-value: 0.12
                  HHHHHHHHHH......HHSSSCT-TT-S--CHHHHHH CS
  HTH_Tnp_Tc5  26 lirekAqela......slaadlgepdfkaSkgWldrF 56 
                  +i e + +++       +++d+g+++ +  ++Wl++F
   EEA23008.1 229 AILESWFKYLkeedwlITISDKGYSNDTIAYEWLQHF 265
                  5555555555555555455788888889999999998 PP

>> Med9  RNA polymerase II transcription mediator complex subunit 9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0       0.4   1.2e+03      37      51 ..     201     215 ..     200     218 .. 0.87
   2 ?   11.6   0.6   7.5e-05      0.22      18      70 ..     430     486 ..     409     491 .. 0.77

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.4
        Med9  37 karelirelpgidrs 51 
                 + rel+++++gi+ +
  EEA23008.1 201 SSRELVSTIEGISAT 215
                 679*********987 PP

  == domain 2  score: 11.6 bits;  conditional E-value: 7.5e-05
        Med9  18 nlsskdletktgelrhkLkkarelirelpg....idrsveeqeaeieeleeqlakKr 70 
                 ++s+++++t+++e+ + +  +r  ++++ +      + +++q+a+ie l+  +a+K 
  EEA23008.1 430 QRSINKVDTQLNEISDAIPGIRRRLKKIFDgsltQAHIKDQQQAQIERLQTLNARKS 486
                 588888888888888888888888888888555445557899999999999888886 PP

>> DUF1359  Protein of unknown function (DUF1359)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   1.2   5.1e-05      0.15       6      82 ..     428     506 ..     424     520 .. 0.86

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 5.1e-05
     DUF1359   6 kirrniekveqkiarlkdvihdvkdqtelvklleddlksneikkddklele....ltdrfsvlkssvkinvGtlisllkdn 82 
                 k++r i+kv++++  + d i  ++++  l k+    l + +ik +++ ++e    l  r s  ks+ +++vG ++++ + n
  EEA23008.1 428 KLQRSINKVDTQLNEISDAIPGIRRR--LKKIFDGSLTQAHIKDQQQAQIErlqtLNARKSAKKSKRQVQVGGILTVKDAN 506
                 7899**********************..99*************98887765444478899999999999999998876655 PP

>> HTH_24  Winged helix-turn-helix DNA-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   7.6e-05      0.23       9      38 ..      17      46 ..      11      47 .. 0.94

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 7.6e-05
      HTH_24  9 LelLqknprisqreLAerlglSpstvnrrl 38
                Le+L+knp+  ++ LA++ g+  + ++rr+
  EEA23008.1 17 LEILRKNPKQKIKPLARQFGVDYQRLRRRV 46
                9***********************999997 PP

>> HTH_AsnC-type  AsnC-type helix-turn-helix domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.0   0.00016      0.46       9      38 ..      17      46 ..      16      47 .. 0.97
   2 ?   -1.1   0.0      0.57   1.7e+03       3      19 ..     547     565 ..     547     568 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00016
  HTH_AsnC-type  9 LeaLqedaRisyaeLAervGlSestvlrRv 38
                   Le+L+++++   + LA++ G++ ++ +rRv
     EEA23008.1 17 LEILRKNPKQKIKPLARQFGVDYQRLRRRV 46
                   89***************************8 PP

  == domain 2  score: -1.1 bits;  conditional E-value: 0.57
  HTH_AsnC-type   3 eiDrkILeaLqed..aRis 19 
                    +iDr I+  L e+  +R+s
     EEA23008.1 547 AIDRNIILNLVEQvyPRRS 565
                    59****9999888777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (577 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1065  (0.059401); expected 358.6 (0.02)
Passed bias filter:                      619  (0.0345251); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.68u 0.30s 00:00:00.98 Elapsed: 00:00:00.47
# Mc/sec: 3678.86
//
Query:       EEA23009.1  [L=141]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (141 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       351  (0.0195772); expected 358.6 (0.02)
Passed bias filter:                      246  (0.0137208); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.24s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 1041.24
//
Query:       EEA23010.1  [L=278]
Description: cell polarity protein (Alp11), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    8.3e-25   86.6   0.0    1.3e-24   86.0   0.0    1.3  1  CAP_GLY      CAP-Gly domain
    3.5e-14   53.0   0.0    6.2e-14   52.2   0.0    1.4  1  Ubiquitin_2  Ubiquitin-like domain
    1.2e-05   25.0   0.0      3e-05   23.7   0.0    1.6  1  ubiquitin    Ubiquitin family


Domain annotation for each model (and alignments):
>> CAP_GLY  CAP-Gly domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.0   0.0   2.1e-28   1.3e-24       7      65 .]     180     257 ..     170     257 .. 0.80

  Alignments for each domain:
  == domain 1  score: 86.0 bits;  conditional E-value: 2.1e-28
     CAP_GLY   7 lkegrrGvvryvGpvp........fakg............ewvGveldepnGkndGsvkgkrYFeck.pnrGvFvrpekv 65 
                 +++ rrG+vry+Gpv         +  +             wvG+eldep+GkndGs+ gkrYFec  +nrGvFv+pekv
  EEA23010.1 180 PPHIRRGTVRYIGPVTeipfaplkD--KkvttedghplepLWVGIELDEPTGKNDGSIAGKRYFECAgNNRGVFVKPEKV 257
                 7899**********96555444431..14555556777667*************************8578********97 PP

>> Ubiquitin_2  Ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.2   0.0     1e-17   6.2e-14      13      86 ..      28      99 ..      16     100 .. 0.90

  Alignments for each domain:
  == domain 1  score: 52.2 bits;  conditional E-value: 1e-17
                 .SEEEEEEETTSBHHHHHHHHHHHH---TTCEEEEEE.-SSSSEEECSSGCCSBCCCCT--TTEEEEEEE-TT- CS
  Ubiquitin_2 13 avsserrfsksltieelKekLelitGtspasmrLqlyddkkdnevsklddddalLgsYgvkdgmrihViDkdpn 86
                 ++++err+ +s++i++lK+kLe++tG++p s+rL ++  + ++  + ++ +d+l g++g+  g++i V+D++p+
   EEA23010.1 28 SLATERRVTPSWSISQLKRKLETMTGVPPGSQRLLFK--SPGRPDQWIEGEDRLIGEWGLVRGCEIEVHDTRPA 99
                 3789******************************999..77777788999*********************996 PP

>> ubiquitin  Ubiquitin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.7   0.0     5e-09     3e-05      14      44 ..      34      64 ..      25      68 .. 0.94

  Alignments for each domain:
  == domain 1  score: 23.7 bits;  conditional E-value: 5e-09
                EEETTSBHHHHHHHHHHHHTSSGGGEEEEET CS
   ubiquitin 14 eveesdtveelKekiaekegipaeqqrLiys 44
                +v +s+++++lK k++  +g+p+ +qrL+++
  EEA23010.1 34 RVTPSWSISQLKRKLETMTGVPPGSQRLLFK 64
                699***************************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (278 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       273  (0.0152267); expected 358.6 (0.02)
Passed bias filter:                      255  (0.0142228); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.64u 0.34s 00:00:00.98 Elapsed: 00:00:00.58
# Mc/sec: 1443.98
//
Query:       EEA23011.1  [L=278]
Description: cell polarity protein (Alp11), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    8.3e-25   86.6   0.0    1.3e-24   86.0   0.0    1.3  1  CAP_GLY      CAP-Gly domain
    3.5e-14   53.0   0.0    6.2e-14   52.2   0.0    1.4  1  Ubiquitin_2  Ubiquitin-like domain
    1.2e-05   25.0   0.0      3e-05   23.7   0.0    1.6  1  ubiquitin    Ubiquitin family


Domain annotation for each model (and alignments):
>> CAP_GLY  CAP-Gly domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   86.0   0.0   2.1e-28   1.3e-24       7      65 .]     180     257 ..     170     257 .. 0.80

  Alignments for each domain:
  == domain 1  score: 86.0 bits;  conditional E-value: 2.1e-28
     CAP_GLY   7 lkegrrGvvryvGpvp........fakg............ewvGveldepnGkndGsvkgkrYFeck.pnrGvFvrpekv 65 
                 +++ rrG+vry+Gpv         +  +             wvG+eldep+GkndGs+ gkrYFec  +nrGvFv+pekv
  EEA23011.1 180 PPHIRRGTVRYIGPVTeipfaplkD--KkvttedghplepLWVGIELDEPTGKNDGSIAGKRYFECAgNNRGVFVKPEKV 257
                 7899**********96555444431..14555556777667*************************8578********97 PP

>> Ubiquitin_2  Ubiquitin-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.2   0.0     1e-17   6.2e-14      13      86 ..      28      99 ..      16     100 .. 0.90

  Alignments for each domain:
  == domain 1  score: 52.2 bits;  conditional E-value: 1e-17
                 .SEEEEEEETTSBHHHHHHHHHHHH---TTCEEEEEE.-SSSSEEECSSGCCSBCCCCT--TTEEEEEEE-TT- CS
  Ubiquitin_2 13 avsserrfsksltieelKekLelitGtspasmrLqlyddkkdnevsklddddalLgsYgvkdgmrihViDkdpn 86
                 ++++err+ +s++i++lK+kLe++tG++p s+rL ++  + ++  + ++ +d+l g++g+  g++i V+D++p+
   EEA23011.1 28 SLATERRVTPSWSISQLKRKLETMTGVPPGSQRLLFK--SPGRPDQWIEGEDRLIGEWGLVRGCEIEVHDTRPA 99
                 3789******************************999..77777788999*********************996 PP

>> ubiquitin  Ubiquitin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.7   0.0     5e-09     3e-05      14      44 ..      34      64 ..      25      68 .. 0.94

  Alignments for each domain:
  == domain 1  score: 23.7 bits;  conditional E-value: 5e-09
                EEETTSBHHHHHHHHHHHHTSSGGGEEEEET CS
   ubiquitin 14 eveesdtveelKekiaekegipaeqqrLiys 44
                +v +s+++++lK k++  +g+p+ +qrL+++
  EEA23011.1 34 RVTPSWSISQLKRKLETMTGVPPGSQRLLFK 64
                699***************************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (278 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       273  (0.0152267); expected 358.6 (0.02)
Passed bias filter:                      255  (0.0142228); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.63u 0.36s 00:00:00.99 Elapsed: 00:00:00.58
# Mc/sec: 1446.07
//
Query:       EEA23012.1  [L=274]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.2e-13   49.5   0.0    9.8e-13   48.6   0.0    1.5  1  Methyltransf_11  Methyltransferase domain
    4.1e-11   43.4   0.0    8.3e-11   42.5   0.0    1.5  1  Methyltransf_25  Methyltransferase domain
    5.8e-08   32.7   0.0    5.2e-07   29.6   0.0    2.1  2  Methyltransf_23  Methyltransferase domain
    2.3e-06   28.3   0.0    5.2e-06   27.1   0.0    1.6  1  Methyltransf_12  Methyltransferase domain
      8e-06   25.7   0.0    1.6e-05   24.8   0.0    1.4  1  Methyltransf_31  Methyltransferase domain
     0.0095   16.1   0.0      0.018   15.2   0.0    1.5  1  DnaB_bind        DnaB-helicase binding domain of primase
  ------ inclusion threshold ------
       0.14   11.7   0.0        0.2   11.2   0.0    1.3  1  MetW             Methionine biosynthesis protein MetW


Domain annotation for each model (and alignments):
>> Methyltransf_11  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.6   0.0   3.8e-16   9.8e-13       1      90 [.      68     153 ..      68     154 .. 0.90

  Alignments for each domain:
  == domain 1  score: 48.6 bits;  conditional E-value: 3.8e-16
                      EEET-TTSHHHHHHHHTTSEEEEEES-HHHHHHHHHHCCHHT-EEEETTEECCCTSS-TT-EEEEEEES-CCC-...CCHHHHHHHHHHHEEE CS
  Methyltransf_11   1 LdvGcGtGrlaealakrgarvvgvDlskemlklakekaseeglkvefvvadaeklpfednsfDlvvssevlhhv...edpekalkeiaRvLkp 90 
                      Ld+GcG+G++++  ++    +++ D s++++++a ++++ +      vvad+ +lp ++++fD+ +s  v+hh+   e++ +a++ i + Lkp
       EEA23012.1  68 LDIGCGNGKYLKVNQNV--FIIASDRSDALVQIATQHQPHST-----VVADILNLPHPESYFDFAISIAVVHHLstpERRVQAISAILQTLKP 153
                      8***********99955..5**************99999998.....***************************7777777777777777777 PP

>> Methyltransf_25  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.5   0.0   3.2e-14   8.3e-11       2      95 ..      68     153 ..      68     154 .. 0.89

  Alignments for each domain:
  == domain 1  score: 42.5 bits;  conditional E-value: 3.2e-14
                      EEET-TTSHHHHHHHCTSTSSEEEEEESSHHHHHHHHHHHHHTTTTEEEEESBCCGBSSSTTTEEEEEEESTGGGSS.HHHHHHHHHHHHHHEE CS
  Methyltransf_25   2 LdlGcGtGrltlalakrlgkakvtgvDiseemleaareraeeeglnvefvqgdaedlpfedgsfDlvvssgalhhls.dedlekalkeiarvLk 94 
                      Ld+GcG+G++++  ++      +++ D s++++++a ++        + v++d+ +lp +++ fD+ +s+ ++hhls +e++ +a++ i + Lk
       EEA23012.1  68 LDIGCGNGKYLKVNQNV----FIIASDRSDALVQIATQHQ-----PHSTVVADILNLPHPESYFDFAISIAVVHHLStPERRVQAISAILQTLK 152
                      8*******998777655....6****************99.....7899********************877999651556789*********9 PP

                      E CS
  Methyltransf_25  95 p 95 
                      p
       EEA23012.1 153 P 153
                      8 PP

>> Methyltransf_23  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.6   0.0     2e-10   5.2e-07      11     109 ..      52     148 ..      41     153 .. 0.76
   2 ?    0.8   0.0      0.15   3.9e+02     139     163 ..     231     255 ..     166     257 .. 0.78

  Alignments for each domain:
  == domain 1  score: 29.6 bits;  conditional E-value: 2e-10
  Methyltransf_23  11 dklerllpklraggrvLdiGcGtGillevlrengfsvtgvDlspeaveiaekakkaqkdqfdeq...eaaepqgkfdlIvlrevlehvpdppel 101
                        +er+l ++++g+  LdiGcG G  l+v   + + +++ D s+++v+ia    + q++++      + + p+ +fd+++++ v +h+  p++ 
       EEA23012.1  52 PIVERFLLEQKPGSIGLDIGCGNGKYLKVN--QNVFIIASDRSDALVQIA---TQHQPHSTVVAdilNLPHPESYFDFAISIAVVHHLSTPERR 140
                      56788888899999**********777744..455799**********98...333333332331224455999******************88 PP

  Methyltransf_23 102 lrqiatll 109
                      ++ i ++l
       EEA23012.1 141 VQAISAIL 148
                      88888776 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.15
  Methyltransf_23 139 agrhisffsarslkelleeaGlevv 163
                       +r  +++ + +l+++ ++aG  v+
       EEA23012.1 231 FHRFYHLYEENELERDIRAAGGVVI 255
                      2367799999999999999996666 PP

>> Methyltransf_12  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.1   0.0     2e-09   5.2e-06       1      95 [.      68     153 ..      68     154 .. 0.71

  Alignments for each domain:
  == domain 1  score: 27.1 bits;  conditional E-value: 2e-09
  Methyltransf_12   1 LeiGcGtGsllralleklpdieytgvDispsaiedakeklakrennnnnnvelealdlldldggssfDlvvasnvlhhl...kdirevldnirk 91 
                      L+iGcG+G +l++  +      ++++D s + + + +++++ ++   ++ ++l +        +s+fD  +++ v+hhl   + + ++++ i +
       EEA23012.1  68 LDIGCGNGKYLKVNQNV----FIIASDRSDALV-QIATQHQPHSTVVADILNLPHP-------ESYFDFAISIAVVHHLstpERRVQAISAILQ 149
                      8*******999887555....999*********.3333333333333333333333.......35**************885555588888888 PP

  Methyltransf_12  92 lLkp 95 
                       Lkp
       EEA23012.1 150 TLKP 153
                      8887 PP

>> Methyltransf_31  Methyltransferase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.8   0.0   6.1e-09   1.6e-05       8     100 ..      68     147 ..      62     153 .. 0.84

  Alignments for each domain:
  == domain 1  score: 24.8 bits;  conditional E-value: 6.1e-09
  Methyltransf_31   8 lDlGCGtGeltfelaeelgpkaevvGiDiseeaielArenaqklgldnveFeqgdieeleklledekfDlilsnevlnaladpdkileeierv 100
                      lD+GCG+G+++     +++++  ++  D+s   ++ A+++      +  +  ++di +l+    ++ fD+ +s +v+++l+ p+   + i+  
       EEA23012.1  68 LDIGCGNGKYL-----KVNQNVFIIASDRSDALVQIATQH------QPHSTVVADILNLP--HPESYFDFAISIAVVHHLSTPERRVQAISAI 147
                      9*******987.....5677899****************7......3345579*******..56789*************9999877766554 PP

>> DnaB_bind  DnaB-helicase binding domain of primase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   7.2e-06     0.018       2      36 ..     123     156 ..     122     159 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 7.2e-06
                 HHHHHHTTTT--TTSHHHHHHHHHHHHHHHTTSSS CS
   DnaB_bind   2 eFlierllegydlstpegkaravrealpllaripd 36 
                 +F+i+ ++  + lstpe +++a++++l++l  +pd
  EEA23012.1 123 DFAISIAVV-HHLSTPERRVQAISAILQTLKPVPD 156
                 666666555.789********************99 PP

>> MetW  Methionine biosynthesis protein MetW
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   7.9e-05       0.2      12      33 ..      62      83 ..      53     143 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 7.9e-05
        MetW 12 kpgsrvldlGcGdGellellke 33
                kpgs  ld+GcG+G+ l++ ++
  EEA23012.1 62 KPGSIGLDIGCGNGKYLKVNQN 83
                689999***********99876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (274 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       656  (0.0365888); expected 358.6 (0.02)
Passed bias filter:                      465  (0.0259356); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.64u 0.34s 00:00:00.98 Elapsed: 00:00:00.55
# Mc/sec: 1488.40
//
Query:       EEA23013.1  [L=399]
Description: MYB DNA-binding domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.6e-12   47.4   2.8    7.8e-10   38.8   0.0    2.3  2  Myb_DNA-binding  Myb-like DNA-binding domain
    0.00014   22.0   4.0      0.014   15.7   0.1    2.6  2  Myb_DNA-bind_6   Myb-like DNA-binding domain
  ------ inclusion threshold ------
       0.24   10.5   2.7       0.45    9.6   2.7    1.4  1  Roughex          Drosophila roughex protein
       0.27   10.8   8.8       0.58    9.7   8.8    1.5  1  Spt20            Spt20 family


Domain annotation for each model (and alignments):
>> Myb_DNA-binding  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   38.8   0.0   1.7e-13   7.8e-10       2      46 .]     132     175 ..     131     175 .. 0.97
   2 !    8.3   0.9   0.00056       2.5       1      30 [.     178     208 ..     178     217 .. 0.88

  Alignments for each domain:
  == domain 1  score: 38.8 bits;  conditional E-value: 1.7e-13
                      SSSBHHHHHHHHHHHHHHTTCHHHHHHHHTSS-HHHHHHHHHHHT CS
  Myb_DNA-binding   2 gkWteeEdelLleavkkhGnrWkkIaerlggRtekqcrsrwrnyl 46 
                      +kW+ +Ed l++e+  + G +W+ I+++l+gR++ +cr++++nyl
       EEA23013.1 132 SKWSSDEDALIIELRGR-GMKWEDISKKLPGRSAISCRLHYQNYL 175
                      69*************99.9*************************7 PP

  == domain 2  score: 8.3 bits;  conditional E-value: 0.00056
                      CSSSBHHHHHHHHHHHHHHT.TCHHHHHHHH CS
  Myb_DNA-binding   1 rgkWteeEdelLleavkkhG.nrWkkIaerl 30 
                      r++W e+  ++L+++ +++  + W+k+ae++
       EEA23013.1 178 RSEWDEDRKNKLARLYERFKaEMWAKVAEEM 208
                      689*****************999******88 PP

>> Myb_DNA-bind_6  Myb-like DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.1   3.1e-06     0.014       1      44 [.     134     176 ..     134     180 .. 0.87
   2 !    6.7   0.9    0.0019       8.4       1      28 [.     181     209 ..     181     224 .. 0.84

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 3.1e-06
  Myb_DNA-bind_6   1 WteeEdeiLlklvekygndWknIaealnrRtpkqcfdrwknkLr 44 
                     W+ +Ed ++++l  + g +W+ I++ l+ R++ +c+ +++n L 
      EEA23013.1 134 WSSDEDALIIELRGR-GMKWEDISKKLPGRSAISCRLHYQNYLE 176
                     999999999999876.68*********55************874 PP

  == domain 2  score: 6.7 bits;  conditional E-value: 0.0019
  Myb_DNA-bind_6   1 WteeEdeiLlklvekyg.ndWknIaealn 28 
                     W+e+ + +L++l+e++    W ++ae+++
      EEA23013.1 181 WDEDRKNKLARLYERFKaEMWAKVAEEMA 209
                     9999999*********8357*******97 PP

>> Roughex  Drosophila roughex protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.6   2.7    0.0001      0.45     273     321 ..      23      76 ..      10     108 .. 0.58

  Alignments for each domain:
  == domain 1  score: 9.6 bits;  conditional E-value: 0.0001
     Roughex 273 dlpdqnkeedkdeqeqqaeqeeqa....qqqaeeapvssdistalk.etnppae 321
                   pd+++e+    q+qq  q++q+    qqq  + p+ss++s+a    t   a 
  EEA23013.1  23 LKPDDEEENPPSHQQQQQYQQHQHqqtyQQQQINRPTSSSSSAASSrRTSMLAS 76 
                 456665555544333333332222011145555669999998886414554454 PP

>> Spt20  Spt20 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   8.8   0.00013      0.58     106     146 ..      32      72 ..      18      87 .. 0.59

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00013
       Spt20 106 dqkqsqqnqqqqqqqqqqqqqqqqqqeqqqqqnekdsttte 146
                 + + +qq+q+qq q qq++qqqq ++ +++++++  s+ t+
  EEA23013.1  32 PPSHQQQQQYQQHQHQQTYQQQQINRPTSSSSSAASSRRTS 72 
                 33333356666666666666666666666666666655555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (399 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1657  (0.0924201); expected 358.6 (0.02)
Passed bias filter:                      781  (0.0435607); expected 358.6 (0.02)
Passed Vit filter:                        88  (0.00490825); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.79u 0.37s 00:00:01.16 Elapsed: 00:00:00.55
# Mc/sec: 2172.79
//
Query:       EEA23014.1  [L=370]
Description: hypothetical protein PMAA_096150 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.7e-11   41.7   0.1    1.7e-10   40.8   0.1    1.5  1  SRR1      SRR1


Domain annotation for each model (and alignments):
>> SRR1  SRR1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   40.8   0.1   9.5e-15   1.7e-10       1      53 [.     240     310 ..     240     311 .. 0.92

  Alignments for each domain:
  == domain 1  score: 40.8 bits;  conditional E-value: 9.5e-15
        SRR1   1 ivclGLGsfse.....sssaryQLAlllelveelkiessrs.............vyaqDPvftevDkalLe 53 
                 iv++++Gs++      + ++ yQ+ l+ +l+e l+++++++             +++qDP++t+ D+++L+
  EEA23014.1 240 IVAFACGSITHcddrsKGRSCYQHGLIKTLREILTRARQEDvsltreqrdeqiqCFIQDPAYTDIDREILQ 310
                 8**********8776555666*****************999****************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (370 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       606  (0.0338); expected 358.6 (0.02)
Passed bias filter:                      444  (0.0247643); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.71u 0.36s 00:00:01.06 Elapsed: 00:00:00.59
# Mc/sec: 1880.97
//
Query:       EEA23015.1  [L=639]
Description: mRNA cleavage factor complex component Pcf11, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    4.3e-09   36.7   2.6    2.9e-08   34.1   2.6    2.5  1  CFIA_Pcf11  Subunit of cleavage factor IA Pcf11
    5.3e-06   27.2   0.0    1.6e-05   25.6   0.0    1.9  1  CTD_bind    RNA polymerase II-binding domain.
  ------ inclusion threshold ------
      0.019   14.8   0.0      0.043   13.7   0.0    1.5  1  VHS         VHS domain
        1.6    8.4   6.3        2.7    7.7   1.6    2.8  2  zf_UBZ      Ubiquitin-Binding Zinc Finger
        6.3    6.8   5.3         21    5.2   0.1    2.5  2  zf-C2HC_2   zinc-finger of a C2HC-type


Domain annotation for each model (and alignments):
>> CFIA_Pcf11  Subunit of cleavage factor IA Pcf11
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.1   2.6     8e-12   2.9e-08       1      54 [.     479     532 ..     479     549 .. 0.80

  Alignments for each domain:
  == domain 1  score: 34.1 bits;  conditional E-value: 8e-12
                 EXXXXXXXXXXBXBXXXXXHHHHHTXXTHHCHXXXXXXXXXXXXXXXXXXXXXX CS
  CFIA_Pcf11   1 nkkttttakniQsRnWYLddsqWvkfkddeivstksssnktskkasknaatqas 54 
                 n+++t++ k+ Q+R+WY+d+++W+k ++ +++s    +  t +++ +++a++++
  EEA23015.1 479 NQRMTDSIKRGQNRSWYVDERDWIKSREFDDDSGVAGTGGTGTTTAEEEAAKKQ 532
                 799****************************99998888888887777766654 PP

>> CTD_bind  RNA polymerase II-binding domain.
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6   0.0   4.5e-09   1.6e-05       1      59 [.      62     116 ..      62     117 .. 0.95

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 4.5e-09
    CTD_bind   1 kLnllYLaNdvlqnskrkqkdefapaFapvlpeafadaykkapekikkklkrllniWee 59 
                 kL+ lY++++v++n        ++  ++++l ++f +ay   ++++++kl ++l+ W+e
  EEA23015.1  62 KLPALYVVDSVVKNVG----TPYTLFLGRNLYQTFMNAYTLVDQQTRRKLDEMLKTWKE 116
                 89************83....899*****************99***************98 PP

>> VHS  VHS domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   1.2e-05     0.043      34     119 ..      35     116 ..      13     125 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.2e-05
                 HHCS.TCHHHHHHHHHHHHHT-SSHHHHHHHHHHHHHHHHHSHHHHHHHHTSHHHHHHHHHHHHCTTTCHCS.HHHHHHHHHHHHHH CS
         VHS  34 inek.eagpkeavrlikkkinsknphvallaLklldalvkNcGskfhleiaskeflnelvklilekknsklakvkkkvlelleeWad 119
                 i ++  +++   +r+++  i    p   l aL ++d++vkN G++  l  ++     +l++ + + +   +++ ++k+ e+l+ W++
  EEA23015.1  35 IAKEnTEHAMAISRVLENHIRTTPPSQKLPALYVVDSVVKNVGTPYTLFLGR-----NLYQTFMNAYTLVDQQTRRKLDEMLKTWKE 116
                 444437777778899******************************9998876.....355555556666655667788888888875 PP

>> zf_UBZ  Ubiquitin-Binding Zinc Finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.7   1.6   0.00076       2.7       5      25 ..     451     476 ..     447     476 .. 0.69
   2 ?    1.6   0.2     0.057   2.1e+02       4      15 ..     550     561 ..     548     565 .. 0.85

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.00076
      zf_UBZ   5 CerCgkeipese.....lqEHeDwHf 25 
                 C  Cg+++ ++e     ++ H+DwHf
  EEA23015.1 451 CGTCGRRFISTEegkqqKARHLDWHF 476
                 78888888776523333678*****9 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.057
      zf_UBZ   4 lCerCgkeipes 15 
                 +C+ C+++++++
  EEA23015.1 550 PCPICQEKFEST 561
                 7*******9875 PP

>> zf-C2HC_2  zinc-finger of a C2HC-type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   1.5      0.03   1.1e+02       4      12 ..     450     458 ..     449     461 .. 0.88
   2 ?    5.2   0.1    0.0058        21       4      13 ..     550     559 ..     549     563 .. 0.85

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.03
   zf-C2HC_2   4 pCpkCgRsF 12 
                  C  CgR+F
  EEA23015.1 450 RCGTCGRRF 458
                 699*****9 PP

  == domain 2  score: 5.2 bits;  conditional E-value: 0.0058
   zf-C2HC_2   4 pCpkCgRsFn 13 
                 pCp+C  +F 
  EEA23015.1 550 PCPICQEKFE 559
                 9******995 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (639 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       863  (0.0481343); expected 358.6 (0.02)
Passed bias filter:                      610  (0.0340231); expected 358.6 (0.02)
Passed Vit filter:                        64  (0.00356964); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.82u 0.34s 00:00:01.15 Elapsed: 00:00:00.57
# Mc/sec: 3399.01
//
Query:       EEA23016.1  [L=103]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
  ------ inclusion threshold ------
       0.11   13.2   0.1       0.14   12.9   0.1    1.5  1  Inhibitor_I9  Peptidase inhibitor I9


Domain annotation for each model (and alignments):
>> Inhibitor_I9  Peptidase inhibitor I9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.9   0.1   7.7e-06      0.14      41      67 ..      55      80 ..       6      97 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 7.7e-06
                  EEEEESSSSSEEEEEE-GGGHHHHHTS CS
  Inhibitor_I9 41 ilysYkilfnGfavklteeqaeklrkr 67
                  i +++  lf+Gfa+k  ++++e+++ +
    EEA23016.1 55 ITHEFI-LFKGFAAKAPSSVIETIQTS 80
                  555555.9****************875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (103 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       586  (0.0326845); expected 358.6 (0.02)
Passed bias filter:                      477  (0.0266049); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.35s 00:00:00.91 Elapsed: 00:00:00.56
# Mc/sec: 558.06
//
Query:       EEA23017.1  [L=778]
Description: microtubule binding protein HOOK3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    3.2e-22   78.5  73.6    6.1e-20   71.0  73.6    2.4  1  HOOK            HOOK protein
  ------ inclusion threshold ------
      0.031   14.5   1.6      0.031   14.5   1.6    7.3  8  HALZ            Homeobox associated leucine zipper
       0.29   11.2  93.0      0.057   13.5   2.5    7.6  6  TPR_MLP1_2      TPR/MLP1/MLP2-like protein
        2.9    7.7  88.4      0.017   15.0  21.7    5.9  5  KASH_CCD        Coiled-coil region of CCDC155 or KASH
        4.7    7.2  18.5        2.2    8.3   1.1    5.3  5  Pox_A_type_inc  Viral A-type inclusion protein repeat


Domain annotation for each model (and alignments):
>> HOOK  HOOK protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   71.0  73.6   1.7e-23   6.1e-20       3     691 ..       9     768 ..       7     775 .. 0.68

  Alignments for each domain:
  == domain 1  score: 71.0 bits;  conditional E-value: 1.7e-23
        HOOK   3 esLlkwlqtfnlsapcktvedlsdGvalaqvlnqidpewFtesWlskikedvgdNwrLkvsNlkkilesvleYykevLnqqlsdel..lPdvnkiaeks 99 
                 + Ll+w+++f+l  + +++e+lsdG+ l ++l+ idp++F ++  ++   + +d w  k +Nlk++ + ++ Y +   + ++   l   Pd++ i+e  
  EEA23017.1   9 KVLLEWINSFSLGKTIRDTEELSDGIILWEILQDIDPQYFLDELPER---NPSDHWVTKWQNLKHLHKLLTGYIRKQFDDEIPSGLdpSPDLKAISESN 104
                 68**************************************9998876...78889***************************87542279********* PP

        HOOK 100 dakELgrLlQLiLGcAvnCekKqeyIqqimtleEsvqhvvmtaiQellskegl..............aslseeslgeldsqlrklleelkeaqeekdel 184
                   kE ++Ll L+L +A++  + + y++++ +l    q+ +++ i e  +++ +                l  +   ++++   k+l+e +  ++ek e+
  EEA23017.1 105 SLKETNKLLKLLLIAAISSPNAETYVTTLQKLSTPTQEGLKNIIEEAHNSQHEdlsadeedrdgaakRDLAVDPELQFEERVGKVLAENDRLATEKKEM 203
                 **********************************************99999544666666665444444444444555555666666666666666666 PP

        HOOK 185 aQrcheldkqlsllqeEknaLlaenkklqerlselengeesgtiqltskkylelqkqleqlqeelfrlEtarddyrlkceelekevlelqqrneeltsl 283
                 +  +++l ++l+ lqe + +L++   + ++rl  l +g+  g +  +s+k+le +++    qeel+           k+  ++ e+  l +  e +  +
  EEA23017.1 204 EKALEDLHNRLARLQENNDTLQTRLASTEDRLVTLKSGK--GDV-GFSTKALESRSR---QQEELIAN------QEAKISAAQDEIDSLTMSLESMRVK 290
                 666666666666666666666666666666666666443..344.236666666654...35565533......3345566667788888888899999 PP

        HOOK 284 aeEaqaLkDEvDvLresadkvkkleatvetykkkledlndLrrqvklleernaeYlqktveleeelkkanalrsqlelykkqvqelhkklseeskkadk 382
                  +  q+L+D+ D ++   +++ +  ++ e y++kl+  +d+ ++ + l+++  +  q+  e + + k+ ++   +le y++ +  +++  +e ++  ++
  EEA23017.1 291 NQRFQKLQDDYDEMKTEREQLIRKANAAEKYRQKLQASQDFEKENQALKNQVKDLQQQLKEADSNQKRSSERDVELEEYRRVLPRIEQDRHEIQSLKKQ 389
                 999999*********************************************9999999999999**********************9999999999999 PP

        HOOK 383 lefelkkleeklealqkekerllaerdaLketneELkca.............qlq...qkelsqadalaskssssgenlaaellpaevrekl.irLq.. 462
                 lef++++l+e+l++ + +++r  a    L+e + EL+ +             +lq   qk+l   +a +++ +s++e l++e++  ++ ++l   L+  
  EEA23017.1 390 LEFNNHALTERLQSAEEQRDRDEALISELRERIRELEGStdspsytpgnaspRLQstlQKDLDDIGARETQLKSENEELKKEVHKLKTTNTLgSSLEsy 488
                 *******************99888888999999999764111111111111112211133344444555555567777777877777777774234422 PP

        HOOK 463 hENKmLklkqegseeekltelqelledanrrkneLetenrlanqrileLeaqveelqkalqeqgskaed.ssllkkkleehleklkevqeelqkkkeql 560
                 +EN +L  +  + ++ +  e  +l ++      +++++   a++ i + ++q+++ + +lq    ++ d  +++k   ++ + k++e  +el++k ++l
  EEA23017.1 489 SENLVLTAQLAQAKSSQSDEYWKLYDQY----ADIRQKLADAEDLIDSTKRQLDDARAELQLVSKEKLDmIAEVKDSNSSEITKVREDWDELTRKIHHL 583
                 5888887776666666667777777743....4444444555556666666666666666655544444233334444444444444444444444444 PP

        HOOK 561 e....elepklssnkqkieeleeaLkkkdedlkameerYkkyveK..AksViktLdpkqnpaspaevqalknqlaekdkkieslerevekakl...... 647
                 e      ++ ++      +el++ L +k+  ++a ++ + k +e   A    ++ +   n+  ++ + +lk+  +  +k+ e+l + +e+         
  EEA23017.1 584 EaeidASQALVRDMCVERDELRTLLDEKQAAMRAEDDEFMKEIETllAEFAARAKNENPNAPEKSGIELLKHFAEVTEKSAETLAKRAEHIDQqgdlik 682
                 311103333333333667888888888888888888888888875334444443333333333445555654444444444444444333333333455 PP

        HOOK 648 ..................................lreqeEkLivsAwYnlglalqr.eavderlaalsg.......qgqsFLarQR 691
                                                   ++  e  L++sAwY l   lq+ + + +r  ++++         + +L +QR
  EEA23017.1 683 slqeqikhieeargdeeddsipkqreielqeiinRQSRELALVMSAWYDLQGRLQHnNITVARYRHPASgttggadMQKGWLGKQR 768
                 56677777777777777777777777777777755555557777777776554444044445665555455555554556666666 PP

>> HALZ  Homeobox associated leucine zipper
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.8   1.5     0.077   2.8e+02      18      42 ..     190     214 ..     185     215 .. 0.73
   2 ?   -0.3   0.6      0.35   1.3e+03      16      36 ..     209     229 ..     205     235 .. 0.74
   3 ?   -0.5   0.0      0.43   1.6e+03      15      32 ..     278     295 ..     276     296 .. 0.89
   4 ?    6.2   0.5    0.0034        12      13      33 ..     293     313 ..     290     317 .. 0.82
   5 ?    6.9   3.5     0.002       7.3      25      42 ..     332     349 ..     324     350 .. 0.90
   6 ?   -1.1   0.1      0.64   2.3e+03      34      42 ..     382     390 ..     380     392 .. 0.63
   7 ?   14.5   1.6   8.6e-06     0.031       9      40 ..     446     477 ..     445     479 .. 0.91
   8 ?   -3.4   0.0       3.3   1.2e+04      20      34 ..     572     586 ..     568     588 .. 0.51

  Alignments for each domain:
  == domain 1  score: 1.8 bits;  conditional E-value: 0.077
        HALZ  18 ksdydsLkkenekLkaelqeLkekl 42 
                  +++d L  e+++ ++ l+ L ++l
  EEA23017.1 190 LAENDRLATEKKEMEKALEDLHNRL 214
                 5678888888888888888877765 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.35
        HALZ  16 aLksdydsLkkenekLkaelq 36 
                  L+ +   L++ n++L++ l+
  EEA23017.1 209 DLHNRLARLQENNDTLQTRLA 229
                 455555589999999999876 PP

  == domain 3  score: -0.5 bits;  conditional E-value: 0.43
        HALZ  15 daLksdydsLkkenekLk 32 
                 d+L+++ +s++  n++ +
  EEA23017.1 278 DSLTMSLESMRVKNQRFQ 295
                 99***********99865 PP

  == domain 4  score: 6.2 bits;  conditional E-value: 0.0034
        HALZ  13 sYdaLksdydsLkkenekLka 33 
                 ++ +L+ dyd +k e+e+L  
  EEA23017.1 293 RFQKLQDDYDEMKTEREQLIR 313
                 688999999999999999976 PP

  == domain 5  score: 6.9 bits;  conditional E-value: 0.002
        HALZ  25 kkenekLkaelqeLkekl 42 
                 +ken++Lk++++ L ++l
  EEA23017.1 332 EKENQALKNQVKDLQQQL 349
                 79************9987 PP

  == domain 6  score: -1.1 bits;  conditional E-value: 0.64
        HALZ  34 elqeLkekl 42 
                 e+q+Lk++l
  EEA23017.1 382 EIQSLKKQL 390
                 667777665 PP

  == domain 7  score: 14.5 bits;  conditional E-value: 8.6e-06
        HALZ   9 vLKasYdaLksdydsLkkenekLkaelqeLke 40 
                 +L+++ d   ++  +Lk ene+Lk+e+++Lk 
  EEA23017.1 446 TLQKDLDDIGARETQLKSENEELKKEVHKLKT 477
                 68899999999999****************95 PP

  == domain 8  score: -3.4 bits;  conditional E-value: 3.3
        HALZ  20 dydsLkkenekLkae 34 
                 d+d L +  + L+ae
  EEA23017.1 572 DWDELTRKIHHLEAE 586
                 445555555555555 PP

>> TPR_MLP1_2  TPR/MLP1/MLP2-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.5   2.5   1.6e-05     0.057      86     127 ..     188     229 ..     170     231 .. 0.87
   2 ?   -0.8  25.6      0.41   1.5e+03       4     110 ..     250     354 ..     238     363 .. 0.71
   3 ?   11.4   6.9     7e-05      0.25      65     116 ..     375     426 ..     364     428 .. 0.89
   4 ?    5.7  15.4     0.004        14       4     120 ..     445     563 ..     443     564 .. 0.90
   5 ?    7.7   2.9   0.00099       3.6      56     115 ..     563     622 ..     557     635 .. 0.74
   6 ?    0.4   2.1      0.18   6.3e+02       5      43 ..     658     696 ..     652     729 .. 0.77

  Alignments for each domain:
  == domain 1  score: 13.5 bits;  conditional E-value: 1.6e-05
  TPR_MLP1_2  86 eleeseesweeqkeelekelselekriedlneqNklLhdQlE 127
                 ++ ++   ++++k+e+ek l++l +r+  l+e N++L ++l 
  EEA23017.1 188 KVLAENDRLATEKKEMEKALEDLHNRLARLQENNDTLQTRLA 229
                 5667788999***************************99985 PP

  == domain 2  score: -0.8 bits;  conditional E-value: 0.41
  TPR_MLP1_2   4 ksleeeikslkeekeeaeaklqklqedlekqaeiakeaqqkYerelvkhaedvkelqalreelnelkaeiaelkaeaesakaeleeseesweeqkeele 102
                 k+le+   + +e ++++eak++++q+++ + + +++ +  k  +  +k  +d +e+++ re+l +  + +++ +++++ a++++e++ +++++q + l+
  EEA23017.1 250 KALESRSRQQEELIANQEAKISAAQDEIDSLTMSLESMRVK-NQRFQKLQDDYDEMKTEREQLIRKANAAEKYRQKLQ-ASQDFEKENQALKNQVKDLQ 346
                 56777777777777777777777777777777777777775.445677777777777777777777777777777665.45567777777777777777 PP

  TPR_MLP1_2 103 kelselek 110
                 ++l+e+ +
  EEA23017.1 347 QQLKEADS 354
                 77777654 PP

  == domain 3  score: 11.4 bits;  conditional E-value: 7e-05
  TPR_MLP1_2  65 elnelkaeiaelkaeaesakaeleeseesweeqkeelekelselekriedln 116
                 ++++ + ei++lk+++e  +++l e  +s eeq+++ e  +sel++ri +l+
  EEA23017.1 375 RIEQDRHEIQSLKKQLEFNNHALTERLQSAEEQRDRDEALISELRERIRELE 426
                 568999********************************************96 PP

  == domain 4  score: 5.7 bits;  conditional E-value: 0.004
  TPR_MLP1_2   4 ksleeeikslkeekeeaeaklqklqedlekq..aeiakeaqqkYerelvkhaedvkelqalreelnelkaeiaelkaeaesakaeleeseesweeqkee 100
                 ++l+++++++ +++++++++ ++l++++ k   ++ +    ++Y++ lv+ a+ +++ ++  +e+ +l +++a++++++ +a+  ++  + +++  + e
  EEA23017.1 445 STLQKDLDDIGARETQLKSENEELKKEVHKLktTNTLGSSLESYSENLVLTAQLAQAKSSQSDEYWKLYDQYADIRQKLADAEDLIDSTKRQLDDARAE 543
                 579999999999***************998622466778999********************************************************* PP

  TPR_MLP1_2 101 lekelselekriedlneqNk 120
                 l+   +e    i ++++ N+
  EEA23017.1 544 LQLVSKEKLDMIAEVKDSNS 563
                 *9888888888888887775 PP

  == domain 5  score: 7.7 bits;  conditional E-value: 0.00099
  TPR_MLP1_2  56 vkelqalreelnelkaeiaelkaeaesakaeleeseesweeqkeelekelselekriedl 115
                 + e++++re+ +el+ +i+ l+ae ++ +a +     + +e ++ l+++ + +++  ++ 
  EEA23017.1 563 SSEITKVREDWDELTRKIHHLEAEIDASQALVRDMCVERDELRTLLDEKQAAMRAEDDEF 622
                 678888999999999999999999988888888887777777777777777666655554 PP

  == domain 6  score: 0.4 bits;  conditional E-value: 0.18
  TPR_MLP1_2   5 sleeeikslkeekeeaeaklqklqedlekqaeiakeaqq 43 
                 +++e+ ++ +++ +e+ +++  l + l++q +  +ea  
  EEA23017.1 658 EVTEKSAETLAKRAEHIDQQGDLIKSLQEQIKHIEEARG 696
                 667777778888888888888888888888888888765 PP

>> KASH_CCD  Coiled-coil region of CCDC155 or KASH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5  12.6   0.00011      0.39      82     175 ..     192     292 ..     169     296 .. 0.67
   2 ?    7.2  21.7    0.0011         4      25     124 ..     264     358 ..     244     363 .. 0.80
   3 ?   15.0  21.7   4.6e-06     0.017      26     132 ..     324     429 ..     322     431 .. 0.90
   4 ?   -0.4  20.4      0.25     9e+02      18     180 ..     459     632 ..     444     634 .. 0.52
   5 ?   -4.8   9.9         5   1.8e+04      66     159 ..     617     708 ..     597     739 .. 0.56

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00011
    KASH_CCD  82 krarlkaqnkqlekenqsLiakiesLqeenikllaekdelkkklkeLlk.......ekaeLkkqlheleellaekealleektkqieeLkltieEyssi 173
                 ++ rl++++k++ek  + L  +++ Lqe+n  l++     + +l  L +       ++  L ++  + eel+a++ea ++  + +i++L++++e +++ 
  EEA23017.1 192 ENDRLATEKKEMEKALEDLHNRLARLQENNDTLQTRLASTEDRLVTLKSgkgdvgfSTKALESRSRQQEELIANQEAKISAAQDEIDSLTMSLESMRVK 290
                 467889999999999999999999999999877766666555555555411111115556777777777777777777777777777777777766655 PP

    KASH_CCD 174 ie 175
                 ++
  EEA23017.1 291 NQ 292
                 54 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0011
    KASH_CCD  25 skLkkavetaeetnakLteeieeLkkklkstQqalqkaklleeEleelkalvkeleEkrarlkaqnkqlekenqsLiakiesLqeenikllaekdelkk 123
                 +   +++ +a+++   Lt  +e ++ k +  Q++   +  ++ E e+l + ++  e  r++l+a  +  ekenq L+ ++++Lq++++     +d ++k
  EEA23017.1 264 ANQEAKISAAQDEIDSLTMSLESMRVKNQRFQKLQDDYDEMKTEREQLIRKANAAEKYRQKLQAS-QDFEKENQALKNQVKDLQQQLKE----ADSNQK 357
                 4445667777788888999999*****************************99999999999885.689***************88654....444444 PP

    KASH_CCD 124 k 124
                 +
  EEA23017.1 358 R 358
                 4 PP

  == domain 3  score: 15.0 bits;  conditional E-value: 4.6e-06
    KASH_CCD  26 kLkkavetaeetnakLteeieeLkkklkstQqalqkaklleeEleelkalvkeleEkrarlkaqnkqlekenqsLiakiesLqeenikllaekdelkkk 124
                 kL+++    e +n+ L + +++L+++lk      ++    + Elee ++++ ++e  r++++  +kqle +n  L+++++s +e+  +  a ++el+++
  EEA23017.1 324 KLQASQ-DFEKENQALKNQVKDLQQQLKEADSNQKRSSERDVELEEYRRVLPRIEQDRHEIQSLKKQLEFNNHALTERLQSAEEQRDRDEALISELRER 421
                 565554.46888999999999999999999888888888899********************************************************* PP

    KASH_CCD 125 lkeLlkek 132
                 ++eL  ++
  EEA23017.1 422 IRELEGST 429
                 ***97665 PP

  == domain 4  score: -0.4 bits;  conditional E-value: 0.25
    KASH_CCD  18 kkLaeenskLkkavetaeetn...akLte..eieeLkkklkstQqa.lqkaklleeEleelkalvkeleEkrarlkaqnkqlekenqsLi.akiesLqe 109
                  +L+ en+ Lkk v +   tn   + L    e+  L  +l     + + ++  l +  +++++ + + e+   + k q   +  e q  + +k++ + e
  EEA23017.1 459 TQLKSENEELKKEVHKLKTTNtlgSSLESysENLVLTAQLAQAKSSqSDEYWKLYDQYADIRQKLADAEDLIDSTKRQLDDARAELQLVSkEKLDMIAE 557
                 555555666655555544444111344431133334433322221102233445566666666666666666666666666666666554245666666 PP

    KASH_CCD 110 enikllaekdelkkklkeLlkekaeLkkqlheleell....aekealleektkqieeLkltieEyssiieeLrae 180
                     + +e+ ++++   eL++++ +L  +++  ++l+    +e+++l +   ++   +++  +E+ + ie+L ae
  EEA23017.1 558 VKDSNSSEITKVREDWDELTRKIHHLEAEIDASQALVrdmcVERDELRTLLDEKQAAMRAEDDEFMKEIETLLAE 632
                 666666666666666666666666666666655555411116677776666666666666666666666666555 PP

  == domain 5  score: -4.8 bits;  conditional E-value: 5
    KASH_CCD  66 eeEleelkalvkeleEkrarlkaqnkql.ekenqsLiakiesLqeenikllaekdelkkklkeLlkekaeLkkqlheleellaekealleektkq 159
                 +e+ e +k++ + l E +ar+k++n ++ ek    L ++ ++  e+    la + e   +  +L+k   +L++q++ +ee  ++ e   + k+++
  EEA23017.1 617 AEDDEFMKEIETLLAEFAARAKNENPNApEKSGIELLKHFAEVTEKSAETLAKRAEHIDQQGDLIK---SLQEQIKHIEEARGDEEDDSIPKQRE 708
                 233333555555566666666666544335555555555555555555555555555555555544...35666666666666555544444444 PP

>> Pox_A_type_inc  Viral A-type inclusion protein repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.1     0.011        40       4      20 ..     336     352 ..     334     355 .. 0.87
   2 ?    3.5   0.6     0.019        69       3      18 ..     376     391 ..     376     391 .. 0.88
   3 ?    8.3   1.1   0.00062       2.2       3      14 ..     415     426 ..     415     428 .. 0.93
   4 ?   -3.2   0.3       2.6   9.3e+03       5      16 ..     460     471 ..     459     471 .. 0.82
   5 ?   -0.1   0.0      0.27   9.8e+02      14      21 ..     534     541 ..     530     542 .. 0.86

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.011
  Pox_A_type_inc   4 srlRsRIsDLErqLseC 20 
                     ++l++ + DL +qL e+
      EEA23017.1 336 QALKNQVKDLQQQLKEA 352
                     589***********997 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.019
  Pox_A_type_inc   3 msrlRsRIsDLErqLs 18 
                     +++ R +I +L++qL+
      EEA23017.1 376 IEQDRHEIQSLKKQLE 391
                     577899*********6 PP

  == domain 3  score: 8.3 bits;  conditional E-value: 0.00062
  Pox_A_type_inc   3 msrlRsRIsDLE 14 
                     +s+lR+RI++LE
      EEA23017.1 415 ISELRERIRELE 426
                     799********9 PP

  == domain 4  score: -3.2 bits;  conditional E-value: 2.6
  Pox_A_type_inc   5 rlRsRIsDLErq 16 
                     +l+s+ ++L+++
      EEA23017.1 460 QLKSENEELKKE 471
                     899998999986 PP

  == domain 5  score: -0.1 bits;  conditional E-value: 0.27
  Pox_A_type_inc  14 ErqLseCr 21 
                     +rqL+++r
      EEA23017.1 534 KRQLDDAR 541
                     8*****98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (778 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3120  (0.17402); expected 358.6 (0.02)
Passed bias filter:                      646  (0.036031); expected 358.6 (0.02)
Passed Vit filter:                       166  (0.00925874); expected 17.9 (0.001)
Passed Fwd filter:                       109  (0.00607954); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 2.71u 0.46s 00:00:03.17 Elapsed: 00:00:00.77
# Mc/sec: 3049.68
//
Query:       EEA23018.1  [L=451]
Description: coproporphyrinogen III oxidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
   8.3e-134  444.9   0.0   3.9e-133  442.7   0.0    1.8  1  Coprogen_oxidas  Coproporphyrinogen III oxidase


Domain annotation for each model (and alignments):
>> Coprogen_oxidas  Coproporphyrinogen III oxidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  442.7   0.0  2.2e-137  3.9e-133       1     296 []     111     451 .]     111     451 .] 0.92

  Alignments for each domain:
  == domain 1  score: 442.7 bits;  conditional E-value: 2.2e-137
  Coprogen_oxidas   1 kveellkelqdeivkaleeldgkakfkedewereeggggisrvledgkvfekagvnvsvvegklpesavkqmraekk....eeleeleffaagv 90 
                      ++e+l+ke+q++i+++l+++d +++f++d+w+r++ggggis+vl+dg+vfekagvn+s+v+g+lp+ a+++mra++k    +++++l+ffaag+
       EEA23018.1 111 RMEKLIKEHQKKITDELSRID-GKAFQADTWTRPNGGGGISCVLQDGNVFEKAGVNISIVYGELPRPAIERMRADHKsfvgANVDSLNFFAAGL 203
                      699******************.889****************************************************9*99999********** PP

  Coprogen_oxidas  91 slvihprnPlvPtvhlnyryfeaee......kkkawWFgGgaDLtPsylfeedavhfHktlkeacdkhdkelypkfKkwcDeyFyikhRkeaRG 178
                      slv+hp+nP++Ptvhlnyryfe+++        k+wWFgGg+DLtPsyl+ ed++hfH+t+k++cd+hd+++yp+fK+wcD+yFyi+hR+eaRG
       EEA23018.1 204 SLVLHPHNPHAPTVHLNYRYFETSDpkdpinGDKNWWFGGGTDLTPSYLYPEDCKHFHQTIKDVCDRHDSTYYPRFKAWCDKYFYIPHRGEARG 297
                      ***********************99877665379************************************************************ PP

  Coprogen_oxidas 179 vGGiffddlk........es....aeelfafvksvgeaflpaYlpivekrkdtpyteeerewqllrrgryveFnLvyDrGtkfGLqte.grves 259
                      +GGiffddl+        +s    +e+lf+fv+++  +flp+Y+pi+e+rkd+p+t e+++wq+lrrgryveFnLvyDrGt+fGL+t+ +rves
       EEA23018.1 298 IGGIFFDDLDanflqsslSSsqnpQETLFSFVSDALGSFLPSYVPILERRKDMPFTPEQKQWQQLRRGRYVEFNLVYDRGTSFGLRTPnARVES 391
                      **********66665555006667********************************************************************** PP

  Coprogen_oxidas 260 iLmslPptarweyelepeegs........................eeaellevlkkpreWv 296
                      iLmslP ta+w y+  p +g+                        ++ e+++vlk+pr+Wv
       EEA23018.1 392 ILMSLPRTASWVYMD-PVSGTrtdasaaaaavlaeetgeqteeisRQMEMMDVLKHPRQWV 451
                      *************96.555554566677777777777777777766677777777777775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (451 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       485  (0.0270511); expected 358.6 (0.02)
Passed bias filter:                      435  (0.0242624); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.70u 0.37s 00:00:01.06 Elapsed: 00:00:00.57
# Mc/sec: 2369.95
//
Query:       EEA23019.1  [L=445]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.6e-16   60.1   2.0    7.3e-16   59.1   0.3    2.1  2  Apc15p    Apc15p protein


Domain annotation for each model (and alignments):
>> Apc15p  Apc15p protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.1   0.3   4.1e-20   7.3e-16      35     123 ..      29     117 ..       8     118 .. 0.77
   2 ?   -0.7   0.1      0.13   2.4e+03      36      60 ..     334     358 ..     299     373 .. 0.59

  Alignments for each domain:
  == domain 1  score: 59.1 bits;  conditional E-value: 4.1e-20
      Apc15p  35 natnkakernedqkksrrsgyapplsaynaieespyyp..rggkldelrmeeeqmerrlkaIrnlGsnwlkPiGvnKTleqireerreaee 123
                 na   + e +++++++ ++g+ + l+++ ++++  + +   +++l+ l++ee+ ++ r+++I+++G  w+kP+G++KT++ +ree++e+ee
  EEA23019.1  29 NA--SSSEPSATRRQQLHNGNGNLLTNAPTSTRAVFSSttPSNSLAMLQLEERALRLRKENIASFGAAWIKPAGIPKTMQGMREEEAEREE 117
                 22..2345566666666666666666666666666555556999*********************************************98 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.13
      Apc15p  36 atnkakernedqkksrrsgyappls 60 
                 +t+ ++++ +++++++ ++  pp +
  EEA23019.1 334 QTPASANTARRGSRRSSTHLPPPPQ 358
                 2222233333333333333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (445 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       654  (0.0364772); expected 358.6 (0.02)
Passed bias filter:                      319  (0.0177924); expected 358.6 (0.02)
Passed Vit filter:                        50  (0.00278878); expected 17.9 (0.001)
Passed Fwd filter:                        23  (0.00128284); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.85u 0.32s 00:00:01.17 Elapsed: 00:00:00.50
# Mc/sec: 2692.85
//
Query:       EEA23020.1  [L=184]
Description: SNARE complex subunit (Bet1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.039   13.7   0.0      0.039   13.7   0.0    1.1  1  Use1      Membrane fusion protein Use1


Domain annotation for each model (and alignments):
>> Use1  Membrane fusion protein Use1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.7   0.0   2.2e-06     0.039     151     241 ..      90     181 ..      32     184 .] 0.85

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 2.2e-06
        Use1 151 davlkkhenlqEklaeemlsLarnLKenslaasqiikkDtetlsksekaadqnlaslkkeserleeh.skskvkcllwlllfvvlvvFismv 241
                 davl   e+  ++  e +   ++ LKe + a+++ i++  +  + + +a d+   +l    +r+ +  ++  v + +w+ +f+ +++ ++ v
  EEA23020.1  90 DAVLSELESQNDNEVEGITAKVKALKELTVAIGDEIRSSSNLADTMNEAFDSTRIRLRGTMNRMLRMaERTGVGWKVWVGFFLAVFLLFAYV 181
                 555555555555556666666899***************************************99976************999887766555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (184 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       733  (0.0408835); expected 358.6 (0.02)
Passed bias filter:                      532  (0.0296726); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 1327.12
//
Query:       EEA23021.1  [L=143]
Description: SNARE complex subunit (Bet1), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (143 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       434  (0.0242066); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.56u 0.34s 00:00:00.90 Elapsed: 00:00:00.55
# Mc/sec: 776.62
//
Query:       EEA23022.1  [L=130]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    8.7e-17   60.3   2.7    8.7e-17   60.3   2.7    3.1  3  CHZ             Histone chaperone domain CHZ
  ------ inclusion threshold ------
          7    4.6  32.5        7.7    4.5  32.5    1.0  1  DNA_pol_phi     DNA polymerase phi


Domain annotation for each model (and alignments):
>> CHZ  Histone chaperone domain CHZ
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.6   2.0       1.8   1.6e+04       2       5 ..      41      44 ..      40      46 .. 0.57
   2 ?   -6.8   6.9         2   1.8e+04       1       6 [.      53      58 ..      49      65 .. 0.80
   3 !   60.3   2.7   9.7e-21   8.7e-17       1      34 []      66      99 ..      66      99 .. 0.97

  Alignments for each domain:
  == domain 1  score: -4.6 bits;  conditional E-value: 1.8
         CHZ  2 eede 5 
                eed+
  EEA23022.1 41 EEDD 44
                5554 PP

  == domain 2  score: -6.8 bits;  conditional E-value: 2
         CHZ  1 eeedeL 6 
                eeede+
  EEA23022.1 53 EEEDEM 58
                788887 PP

  == domain 3  score: 60.3 bits;  conditional E-value: 9.7e-21
         CHZ  1 eeedeLeEIDtsNIIsgGRRTRgktiDfakaaek 34
                +e d+Le+I+ +NII+gGRRTRgk+iDfa+aaek
  EEA23022.1 66 DEGDNLEPISADNIIEGGRRTRGKRIDFAEAAEK 99
                589*****************************98 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5  32.5   0.00086       7.7     647     720 ..      36     128 ..      18     130 .] 0.61

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.00086
  DNA_pol_phi 647 ddeeeeeeddeededseedddeeesdedeededdedvdeid................elreklaealgesgededdddsdsD.....edmdDeqM 720
                   ++ eee+ de++e++ee++++e + ede++++ ++ ++i                 ++ e+ ++a+ +++ d  dd++d+D     ed d + M
   EEA23022.1  36 VNMGEEED-DESSEEEEEEEEDEMGAEDEDEDEGDNLEPISadniieggrrtrgkriDFAEAAEKAKAAGD-DPMDDEDDEDedfhgEDNDGDHM 128
                  33333333.33334444444444555555555555555555667888999*********************.44444444441466655666666 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (130 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1029  (0.0573931); expected 358.6 (0.02)
Passed bias filter:                      489  (0.0272742); expected 358.6 (0.02)
Passed Vit filter:                        97  (0.00541023); expected 17.9 (0.001)
Passed Fwd filter:                        43  (0.00239835); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.75u 0.40s 00:00:01.14 Elapsed: 00:00:00.55
# Mc/sec: 708.77
//
Query:       EEA23023.1  [L=635]
Description: molecular chaperone Hsp70 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   2.4e-258  858.3   6.5   2.7e-258  858.1   6.5    1.0  1  HSP70           Hsp70 protein
    3.5e-19   68.8   0.0    4.6e-18   65.1   0.0    2.1  2  MreB_Mbl        MreB/Mbl protein
     0.0017   18.1   0.0      0.004   16.9   0.0    1.5  1  FGGY_C          FGGY family of carbohydrate kinases, C-termin
     0.0031   17.9   3.2        7.5    7.0   0.0    3.6  3  FtsA            Cell division protein FtsA
  ------ inclusion threshold ------
      0.029   13.6   0.0      0.063   12.5   0.0    1.5  2  StbA            StbA protein
      0.033   13.4   0.1      0.083   12.1   0.1    1.7  1  Hydantoinase_A  Hydantoinase/oxoprolinase
        7.2    6.8   8.0        1.5    9.0   0.0    2.9  3  MetOD2          Metanogen output domain 2


Domain annotation for each model (and alignments):
>> HSP70  Hsp70 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  858.1   6.5  1.1e-261  2.7e-258       1     598 [.       4     606 ..       4     607 .. 0.98

  Alignments for each domain:
  == domain 1  score: 858.1 bits;  conditional E-value: 1.1e-261
                 EEEEEEXSSEEEEEEEETTEEEEEXXTTSXSSEESEEEEXTTSEEETHHHHHCTTTTGGGEEEXGGGTTTXBTTSHHHHHHHTTXSSEEEEETTSBEEE CS
       HSP70   1 viGiDLGttnsvvavmeggkievianeegnrttPsvvaFtkkerlvGeaAkrqavtnpkntvfsvKrliGrkfsdpevqkeikelpykvvkkengkavv 99 
                 +iGiDLGtt+s+v+v+++++ie+ian++gnrttPs+vaFt+ erl+G+aAk+q+++np+ntvf++KrliGrkfsdpevq++ k++p+k+ +k   k+v+
  EEA23023.1   4 AIGIDLGTTYSCVGVFRDDRIEIIANDQGNRTTPSFVAFTDSERLIGDAAKNQVAMNPHNTVFDAKRLIGRKFSDPEVQADAKHFPFKIIEK-ATKPVI 101
                 59*****************************************************************************************9.899*** PP

                 EEEETTE..EEEHHHHHHHHHHHHHHHHHHHHTSBEEEEEEEEXTTXXHHHHHHHHHHHHHTTXEEEEEEEHHHHHHHHHHTCCSS.SCEEEEEEEEXS CS
       HSP70 100 eveaage..kftpeqisamvLkklketaeaylgkkvtdavitvPaYfndaqRqatkdAgkiAGLnvlRivNepTAaalaYGldkkd.kernvlvyDlGg 195
                 eve++ge  +ftpe+is+mvL k++etaeaylg +v++avitvPaYfnd+qRqatkdAg iAGLnvlRi+NepTAaa+aYGldkk   ernvl++DlGg
  EEA23023.1 102 EVEFKGEvkQFTPEEISSMVLIKMRETAEAYLGGTVNNAVITVPAYFNDSQRQATKDAGLIAGLNVLRIINEPTAAAIAYGLDKKVeGERNVLIFDLGG 200
                 *******99**************************************************************************99659*********** PP

                 SXEEEEEEEEETTEEEEEEEEEETTXSHHHHHHHHHHHHHHHHHHHHSXXGGGSHHHHHHHHHHHHHHHHHTTTSSCSEEEEEEEEEETTTEEEEEEEE CS
       HSP70 196 gtfdvSilelekGvfevkaTagDthlGGedfDealvehlveefkkkegidlskdkkalqrlkeaaekaKkeLSsskqteinleietvdedgkdlsekls 294
                 gtfdvS+l++e+G+fevkaTagDthlGGedfD++lv+h+++efk+k++ +l+++ +al+rl++a+e+aK++LSs  ++++++ei++++e g d+ ++++
  EEA23023.1 201 GTFDVSLLTIEDGIFEVKATAGDTHLGGEDFDSRLVNHFASEFKRKYK-NLTTNARALRRLRTACERAKRTLSS--SAQTSIEIDSLFE-GIDFYTSIT 295
                 **********************************************86.899**********************..677788999****.********* PP

                 HHHHHHHHHHHHHHTHHHHHHHHHHCTEEGGGCSEEEEESGGGGSHHHHHHHHHHTTCHHBSSSHTTTHHHHHHHHHHHHHCTC...GCSHCCEEEEBE CS
       HSP70 295 RakfeelvedllertlepvekalkdaklkkeeidevvlvGGstRiPkvqelvkelfgkepsktvnpDeavaiGAAvqagvlsge...eevkdllllDvt 390
                 Ra+feel++dl++ t+epve++l+dak +k+ ++e+vlvGGstRiPk+q+lv ++f+kep+k++npDeava+GAAvqa++lsg+   ++++++lllDv 
  EEA23023.1 296 RARFEELCQDLFRSTMEPVERVLRDAKTDKSSVHEIVLVGGSTRIPKIQKLVTDFFNKEPNKSINPDEAVAYGAAVQAAILSGDtssKSTNEILLLDVA 394
                 ***********************************************************************************97777899******** PP

                 SS-EEEEETTTEEEEEESTTCBSSEEEEEEEEESSTTSSSEEEEEEESSSSBGGGSEEEEEEEEECESSCSTTCSEEEEEEEEETTSCEEEEEEETTTC CS
       HSP70 391 pLslgietlggvmtkliernttiptkksqvfstaadnqtaveievlqgerelvkdnkllgsfeldgippaprGvpqieVtfdidanGiltvsakdketg 489
                 pLs+giet+ggvmt li+rnttiptkks++fst++dnq+ v i+v++ger+ +kdn+llg+fel+gippaprGvpqieVtfd+danGi++vsa +k+tg
  EEA23023.1 395 PLSVGIETAGGVMTPLIKRNTTIPTKKSETFSTYSDNQPGVLIQVYEGERARTKDNNLLGKFELTGIPPAPRGVPQIEVTFDMDANGIMNVSAVEKGTG 493
                 *************************************************************************************************** PP

                 CEEEEEEECCSS.SBHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGGSTHHHH....HHHHHHHHHHHCHTTSSCHHHHHHHH CS
       HSP70 490 keeeitieaseg.lseeeiekmvkdaeesaeedkkkkeaieakneaeelvyslekkleeeaekvseaek....ekvesaieeLkeeleeeekeeieakt 583
                 k+++i i++++g ls+eeie+m  +ae++++ed++++++i+akn +e+++ysl+++l+e + +++++ek    +++e++i++L+++ +++ k+e+ea++
  EEA23023.1 494 KSNKIVITNDKGrLSKEEIERMLAEAEKYKAEDEAEATRIQAKNGLESYAYSLKNTLSEGKLTIDASEKekleAEIEKTISWLDSN-QTATKDEYEAQQ 591
                 ************9***********************************************8888888886688889999999*999.6899******** PP

                 HHHHHHHHHHHHHHH CS
       HSP70 584 eelkkvvekiaekly 598
                 +el++v+++i++++y
  EEA23023.1 592 KELESVANPIISAAY 606
                 *********998776 PP

>> MreB_Mbl  MreB/Mbl protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0     0.046   1.2e+02       3      47 ..       4      54 ..       2      66 .. 0.55
   2 !   65.1   0.0   1.8e-21   4.6e-18      92     317 ..     136     371 ..     106     378 .. 0.84

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.046
                EEEEEE-SSEEEE..EETTTE.EEEEE......ES-EEEETTT--EEEESHHHH CS
    MreB_Mbl  3 dlgiDLGtantlv..yvkgkg.ivlne......psvvAikkktkkvlavGeeAk 47
                 +giDLGt+   v  +  ++  i+ n+      ps vA++ +++    +G+ Ak
  EEA23023.1  4 AIGIDLGTTYSCVgvFRDDRIeIIANDqgnrttPSFVAFTDSERL---IGDAAK 54
                69*******988743555554133332222222666666554432...455555 PP

  == domain 2  score: 65.1 bits;  conditional E-value: 1.8e-21
                 S--EEEEEE-SS--HHHHHHHHHHHHHTT-SEEEEEEHHHHHHHHTT--..TTSSS-EEEEEE-SS-EEEEEEETTE.EEEEEE....ES-SHHHHHHH CS
    MreB_Mbl  92 skprvvicvPsgiteverrAvkeaakkaGarevllieeplaAAiGaglp..veepsgnmvvdiGggttevavislgg.ivtsks....vrvaGdeldea 183
                 + ++ vi+vP   ++ +r+A k+a   aG +   +i+ep aAAi  gl+  ve  +  ++ d+Gggt +v+++++ + i + k+     +++G+++d+ 
  EEA23023.1 136 TVNNAVITVPAYFNDSQRQATKDAGLIAGLNVLRIINEPTAAAIAYGLDkkVEGERNVLIFDLGGGTFDVSLLTIEDgIFEVKAtagdTHLGGEDFDSR 234
                 456889**************************************77775449999999****************97526544432222689******** PP

                 HHHHH....HHHH.SEE--HHHHHHHHHHH-BSS--HHHH.EEEEEEEETTTTCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHTS-HHHHHHHHHH- CS
    MreB_Mbl 184 iikyi....rkky.nlliGertaekikieigsavkeeeee.kmeikGrdlvtglpkevevsseevrealkepvsaiveavkevLektppeLaadivdrg 276
                 ++++     ++ky nl+   r  ++++++   a+ + +++ +++i+   l +g+   ++++ ++ +e  ++ +++ +e v++vL++++ + ++    + 
  EEA23023.1 235 LVNHFasefKRKYkNLTTNARALRRLRTACERAKRTLSSSaQTSIEIDSLFEGIDFYTSITRARFEELCQDLFRSTMEPVERVLRDAKTDKSS---VHE 330
                 **996333356663466666777899999999988877767999********************************************99776...467 PP

                 EEEESGGGGSBTHHHHHHHHHSS-EEE-SSTTTHHHHHHHH CS
    MreB_Mbl 277 ivltGGgallkgldkllseetglpvkvaedpltcvakGtgk 317
                 ivl+GG++ +  ++kl+++ ++ + + + +p ++va G++ 
  EEA23023.1 331 IVLVGGSTRIPKIQKLVTDFFNKEPNKSINPDEAVAYGAAV 371
                 *************************************9875 PP

>> FGGY_C  FGGY family of carbohydrate kinases, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.9   0.0   1.5e-06     0.004     128     196 ..     307     375 ..     262     376 .. 0.79

  Alignments for each domain:
  == domain 1  score: 16.9 bits;  conditional E-value: 1.5e-06
      FGGY_C 128 leavalqlrailealekdsgkpldrlavdGGgskndllmqllAdilg.vpVerpktaeatalGaAilAav 196
                 + +++  +  +l+  + d ++ + +++++GG ++ + +++l  d ++  p +   ++ea+a GaA+ Aa+
  EEA23023.1 307 FRSTMEPVERVLRDAKTD-KSSVHEIVLVGGSTRIPKIQKLVTDFFNkEPNKSINPDEAVAYGAAVQAAI 375
                 334444455555555555.999*************************888888888************96 PP

>> FtsA  Cell division protein FtsA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.0   0.0    0.0029       7.5       1      26 [.       5      27 ..       5     165 .. 0.88
   2 !    6.6   0.0    0.0039        10      36     102 ..     246     367 ..     194     370 .. 0.58
   3 ?    2.4   0.8      0.08   2.1e+02      34     103 .]     501     607 ..     480     609 .. 0.53

  Alignments for each domain:
  == domain 1  score: 7.0 bits;  conditional E-value: 0.0029
                EEEEE-SSSEEEEEEETTEEEEEEEE CS
                xxxxxxxxxxxxxxxxxxxxxxxxxx RF
        FtsA  1 alvDiGagktdvavaedgalvhlrvi 26
                +++D+G++ ++v v++d++   +++i
  EEA23023.1  5 IGIDLGTTYSCVGVFRDDR---IEII 27
                58***************85...4444 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.0039
                 H.........HHHHHT--HHHHHHHHHHH--S--........EEEEEHHHHH............................................... CS
                 x.........xxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxx............................................... RF
        FtsA  36 d.........iakalrtaveeAerikikyGsala........ekeigrkels............................................... 70 
                           + + lrta e A+r      s +a                                                                 
  EEA23023.1 246 KyknlttnarALRRLRTACERAKRTL----SSSAqtsieidsL--------Fegidfytsitrarfeelcqdlfrstmepvervlrdaktdkssvheiv 332
                 15555553455556666666666666....2222123344440........255555556666666677777777777777788888888888888999 PP

                 ...GGGGSTTHHHHHHHHHT-..HHHT-GGGHHHH CS
                 ...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
        FtsA  71 ...ggsalpnleelaeralspkleevsdpeyasal 102
                    g++ +p++++l+ + ++ + ++  +p  a+a+
  EEA23023.1 333 lvgGSTRIPKIQKLVTDFFNKEPNKSINPDEAVAY 367
                 ******************95543445566555555 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.08
                 HHH....HHHHHT--HHHHHHHHHHH--S--....................EEEEEHHHHH.GGGGSTTHHHHHHHHH..............T-..... CS
                 xxx....xxxxxxxxxxxxxxxxxxxxxxxx....................xxxxxxxxxx.xxxxxxxxxxxxxxxx..............xxx.... RF
        FtsA  34 tkd....iakalrtaveeAerikikyGsala....................ekeigrkels.ggsalpnleelaeral..............spk.... 89 
                 t+d     ++ +   ++eAe+ k +                          ++++++ +l+ ++s+ ++le  +e+ +              +      
  EEA23023.1 501 TNDkgrlSKEEIERMLAEAEKYKAE-----DeaeatriqaknglesyayslKNTLSEGKLTiDASEKEKLEAEIEKTIswldsnqtatkdeyE-Aqqke 593
                 4445554334455555666666622.....111112233333333336666555555555587777777777777774334444333333331.03443 PP

                 .HHHT-GGGHHHHH CS
                 xxxxxxxxxxxxxx RF
        FtsA  90 leevsdpeyasalg 103
                 le+v++p +++a+g
  EEA23023.1 594 LESVANPIISAAYG 607
                 44477777777765 PP

>> StbA  StbA protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   2.5e-05     0.063     150     209 ..     178     239 ..     160     289 .. 0.74
   2 ?   -3.6   0.0       1.9   4.9e+03     262     284 ..     318     340 ..     297     362 .. 0.61

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 2.5e-05
        StbA 150 PagfealkeldeleslLiiDlGGttLDvak..vrgklegiskvkgdskiGvslitdavkeal 209
                   ++  +k+++   ++Li DlGG t Dv+   ++  + ++  + gd ++G     + + + +
  EEA23023.1 178 AIAYGLDKKVEGERNVLIFDLGGGTFDVSLltIEDGIFEVKATAGDTHLGGEDFDSRLVNHF 239
                 446778899*******************9722455677777788888888765555555554 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 1.9
        StbA 262 viravsefsgythvmvvGGGael 284
                 +++a +  s +  +++vGG + +
  EEA23023.1 318 LRDAKTDKSSVHEIVLVGGSTRI 340
                 33344444555558888877665 PP

>> Hydantoinase_A  Hydantoinase/oxoprolinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.1   3.2e-05     0.083      58      97 ..     170     209 ..     130     227 .. 0.83

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 3.2e-05
  Hydantoinase_A  58 ilSGPaaGvvgaaatsklagekkvItfDmGGTstDvslik 97 
                     i+  P a ++++    k +ge++v+ fD+GG ++Dvsl+ 
      EEA23023.1 170 IINEPTAAAIAYGLDKKVEGERNVLIFDLGGGTFDVSLLT 209
                     55667777777777789*******************9753 PP

>> MetOD2  Metanogen output domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   0.0   0.00057       1.5      23      72 ..     241     290 ..     231     309 .. 0.88
   2 ?    1.3   0.7      0.14   3.7e+02      49      82 ..     502     535 ..     496     541 .. 0.81
   3 ?   -1.9   0.4       1.5   3.7e+03      51      86 ..     561     596 ..     552     598 .. 0.66

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00057
      MetOD2  23 dEYarLaksvevnkrllslLsqtydidddkaevseeieaalknlekklea 72 
                 +E+ r+ k+   n r l+ L+++++  + ++  s++ ++++ +l +++ +
  EEA23023.1 241 SEFKRKYKNLTTNARALRRLRTACERAKRTLSSSAQTSIEIDSLFEGIDF 290
                 689*****************************************999976 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.14
      MetOD2  49 dddkaevseeieaalknlekkleaqeerlkqikk 82 
                 +d+++   eeie++l + ek   ++e++  +i+ 
  EEA23023.1 502 NDKGRLSKEEIERMLAEAEKYKAEDEAEATRIQA 535
                 555556678999********99999999999976 PP

  == domain 3  score: -1.9 bits;  conditional E-value: 1.5
      MetOD2  51 dkaevseeieaalknlekkleaqeerlkqikkeles 86 
                 +k + ++eie+ ++ l  +  a + + +  +keles
  EEA23023.1 561 EKEKLEAEIEKTISWLDSNQTATKDEYEAQQKELES 596
                 356777777777777777777666666666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (635 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1163  (0.064867); expected 358.6 (0.02)
Passed bias filter:                      674  (0.0375927); expected 358.6 (0.02)
Passed Vit filter:                        69  (0.00384851); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.85u 0.39s 00:00:01.24 Elapsed: 00:00:00.58
# Mc/sec: 3303.94
//
Query:       EEA23024.1  [L=83]
Description: hypothetical protein PMAA_096240 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    5.7e-08   32.3   0.0    8.4e-08   31.8   0.0    1.3  1  NCE101    Non-classical export protein 1


Domain annotation for each model (and alignments):
>> NCE101  Non-classical export protein 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.8   0.0   4.7e-12   8.4e-08       1      31 [.       5      38 ..       5      43 .. 0.84

  Alignments for each domain:
  == domain 1  score: 31.8 bits;  conditional E-value: 4.7e-12
      NCE101  1 YLlsrflDPlLaifiGvaaYylyEk...rterpe 31
                YL+s+++DP++a++iG ++  l+++   r+e+ +
  EEA23024.1  5 YLISKIADPVFALIIGSTSAVLRIQrdmRHESAQ 38
                9************************555555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (83 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       290  (0.0161749); expected 358.6 (0.02)
Passed bias filter:                      234  (0.0130515); expected 358.6 (0.02)
Passed Vit filter:                        16  (0.000892409); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.54u 0.35s 00:00:00.89 Elapsed: 00:00:00.56
# Mc/sec: 447.57
//
Query:       EEA23025.1  [L=309]
Description: mitochondrial GTP/GDP transporter Ggc1, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
    4.3e-29  100.3   2.9    5.2e-14   51.9   0.1    3.2  3  Mito_carr  Mitochondrial carrier protein


Domain annotation for each model (and alignments):
>> Mito_carr  Mitochondrial carrier protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.1   6.7e-08    0.0012       6      91 ..      23     110 ..      18     116 .. 0.70
   2 !   28.9   0.1   4.5e-11   8.2e-07       6      94 ..     132     211 ..     127     213 .. 0.89
   3 !   51.9   0.1   2.9e-18   5.2e-14       4      94 ..     220     306 ..     217     308 .. 0.92

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 6.7e-08
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSS..HHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHH CS
   Mito_carr   6 lkellaGglagavatlvttPldvvKtrlqtqkksskksksaa..ildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkr 91 
                 +++ll +g ag+++ lv +P+d++  rl++++++s+++   +  i++ + +      +++l+ Gl+ +    + ++  k +   ++++
  EEA23025.1  23 TARLLGSGSAGIAELLVFHPVDTIAKRLMSNQGQSNTAAALNqvIFKEYATASVGRKFTSLFPGLGYAAGYKVLQRIYKYGGQPFVRD 110
                 5789999****************98888887776655443224666666666666677888888887776666666666665555555 PP

  == domain 2  score: 28.9 bits;  conditional E-value: 4.5e-11
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
   Mito_carr   6 lkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlll 94 
                 + +  aG++ g++  +v  Pldv+K++ qt+++  + +        l ki+ +eG+ glyrG++ +  r+ap s++ f+   + k++++
  EEA23025.1 132 IMHATAGSIVGIG-EIVLLPLDVLKIKRQTNPEAFRGR-------GLFKIISDEGM-GLYRGAGWTAARNAPGSFALFGGSAFAKEYIF 211
                 5677889999876.8999*****************985.......5779******8.**********************9999999875 PP

  == domain 3  score: 51.9 bits;  conditional E-value: 2.9e-18
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCSSTTTSCSSHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHC CS
   Mito_carr   4 svlkellaGglagavatlvttPldvvKtrlqtqkksskksksaaildvlkkiykeeGlrglyrGllpnllrvapasalkfvlyetlkrlll 94 
                 ++ ++++a+ ++++++ +v +Pldv+Ktr+q+ + ++ +s+     +++ +++k+eG  ++++Gl+p+ll++ p+ +  f+l +tl+  + 
  EEA23025.1 220 TWGQNFVASIFGASASLVVSAPLDVIKTRIQNRNFENPESG----TRIIANMIKNEGAGAFFKGLVPKLLMTGPKLVFSFWLAQTLIPAFG 306
                 67899*******************************99976....5699********************************9999987775 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (309 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       326  (0.0181828); expected 358.6 (0.02)
Passed bias filter:                      277  (0.0154498); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.63u 0.32s 00:00:00.95 Elapsed: 00:00:00.54
# Mc/sec: 1710.65
//
Query:       EEA23026.1  [L=118]
Description: autophagic death protein Aut7/IDI-7, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-51  172.1   0.2    3.2e-51  171.8   0.2    1.0  1  Atg8      Autophagy protein Atg8 ubiquitin like
      3e-06   27.5   0.0    3.6e-06   27.3   0.0    1.2  1  APG12     Ubiquitin-like autophagy protein Apg12


Domain annotation for each model (and alignments):
>> Atg8  Autophagy protein Atg8 ubiquitin like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  171.8   0.2   3.6e-55   3.2e-51       1     104 []      13     116 ..      13     116 .. 0.99

  Alignments for each domain:
  == domain 1  score: 171.8 bits;  conditional E-value: 3.6e-55
                 HHHHHHHHHHHHSTTEEEEEEEE-TTSSS---S-SEEEEETTSBHHHHHHHHHHHTT--TTS-EEEEETTE-SSTTSBHHHHHHHH--TTSSEEEEEES CS
        Atg8   1 krkkesekirekypdriPvivekaekeklpeldkkkylvPedltvgqlvliirkrlqlepekalfllvnetlpstsatmsalyeeekdedgflyvvyss 99 
                 krk+e+e+ir+ky driPvi+ek+ek++++++dkkkylvP+dltvgq+v++irkr++l+peka+f++v+e+lp+t+a ms++yee+kdedgfly++ys+
  EEA23026.1  13 KRKAEAERIRQKYADRIPVICEKVEKSDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTAALMSSIYEEHKDEDGFLYITYSG 111
                 79************************************************************************************************* PP

                 SSTB- CS
        Atg8 100 entfG 104
                 entfG
  EEA23026.1 112 ENTFG 116
                 ****9 PP

>> APG12  Ubiquitin-like autophagy protein Apg12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.0   4.1e-10   3.6e-06      10      87 .]      39     116 ..      28     116 .. 0.89

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 4.1e-10
                 TTS---S--EEEEETTSBHHHHHHHHHHHCT-.SSSS-EEEETTTB---TTSBHHHHHHHH-.BTTEEEEEEESSS--- CS
       APG12  10 gdvpilkkkklkvnasdtvakvilflkkeLklqaseslflYvnnsFaPsPdeeveeLyecfg.tdkklvlnYcisvAfG 87 
                 +d+  + kkk+ v a  tv +++  ++k++kl+ ++ +f++v++   P+    +  +ye ++  d+ l ++Y+ +  fG
  EEA23026.1  39 SDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTA-ALMSSIYEEHKdEDGFLYITYSGENTFG 116
                 5788899*************************************998875.6899*******4555566****999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (118 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       582  (0.0324614); expected 358.6 (0.02)
Passed bias filter:                      469  (0.0261587); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.31s 00:00:00.88 Elapsed: 00:00:00.54
# Mc/sec: 657.12
//
Query:       EEA23027.1  [L=121]
Description: autophagic death protein Aut7/IDI-7, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-48  163.4   0.3    1.6e-48  163.2   0.3    1.1  1  Atg8      Autophagy protein Atg8 ubiquitin like
      3e-06   27.5   0.0    3.8e-06   27.2   0.0    1.2  1  APG12     Ubiquitin-like autophagy protein Apg12


Domain annotation for each model (and alignments):
>> Atg8  Autophagy protein Atg8 ubiquitin like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  163.2   0.3   1.8e-52   1.6e-48       1     104 []      13     119 ..      13     119 .. 0.99

  Alignments for each domain:
  == domain 1  score: 163.2 bits;  conditional E-value: 1.8e-52
                 HHHHHHHHHHHHSTTEEE...EEEEE-TTSSS---S-SEEEEETTSBHHHHHHHHHHHTT--TTS-EEEEETTE-SSTTSBHHHHHHHH--TTSSEEEE CS
        Atg8   1 krkkesekirekypdriP...vivekaekeklpeldkkkylvPedltvgqlvliirkrlqlepekalfllvnetlpstsatmsalyeeekdedgflyvv 96 
                 krk+e+e+ir+ky driP   vi+ek+ek++++++dkkkylvP+dltvgq+v++irkr++l+peka+f++v+e+lp+t+a ms++yee+kdedgfly++
  EEA23027.1  13 KRKAEAERIRQKYADRIPfvkVICEKVEKSDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTAALMSSIYEEHKDEDGFLYIT 111
                 79***************98889***************************************************************************** PP

                 EESSSTB- CS
        Atg8  97 yssentfG 104
                 ys+entfG
  EEA23027.1 112 YSGENTFG 119
                 *******9 PP

>> APG12  Ubiquitin-like autophagy protein Apg12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.2   0.0   4.2e-10   3.8e-06      10      87 .]      42     119 ..      31     119 .. 0.88

  Alignments for each domain:
  == domain 1  score: 27.2 bits;  conditional E-value: 4.2e-10
                 TTS---S--EEEEETTSBHHHHHHHHHHHCT-.SSSS-EEEETTTB---TTSBHHHHHHHH-.BTTEEEEEEESSS--- CS
       APG12  10 gdvpilkkkklkvnasdtvakvilflkkeLklqaseslflYvnnsFaPsPdeeveeLyecfg.tdkklvlnYcisvAfG 87 
                 +d+  + kkk+ v a  tv +++  ++k++kl+ ++ +f++v++   P+    +  +ye ++  d+ l ++Y+ +  fG
  EEA23027.1  42 SDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTA-ALMSSIYEEHKdEDGFLYITYSGENTFG 119
                 5788999*************************************998875.6899*******4555566****999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (121 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       601  (0.0335211); expected 358.6 (0.02)
Passed bias filter:                      490  (0.02733); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.35s 00:00:00.93 Elapsed: 00:00:00.55
# Mc/sec: 665.83
//
Query:       EEA23028.1  [L=118]
Description: autophagic death protein Aut7/IDI-7, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-51  172.1   0.2    3.2e-51  171.8   0.2    1.0  1  Atg8      Autophagy protein Atg8 ubiquitin like
      3e-06   27.5   0.0    3.6e-06   27.3   0.0    1.2  1  APG12     Ubiquitin-like autophagy protein Apg12


Domain annotation for each model (and alignments):
>> Atg8  Autophagy protein Atg8 ubiquitin like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  171.8   0.2   3.6e-55   3.2e-51       1     104 []      13     116 ..      13     116 .. 0.99

  Alignments for each domain:
  == domain 1  score: 171.8 bits;  conditional E-value: 3.6e-55
                 HHHHHHHHHHHHSTTEEEEEEEE-TTSSS---S-SEEEEETTSBHHHHHHHHHHHTT--TTS-EEEEETTE-SSTTSBHHHHHHHH--TTSSEEEEEES CS
        Atg8   1 krkkesekirekypdriPvivekaekeklpeldkkkylvPedltvgqlvliirkrlqlepekalfllvnetlpstsatmsalyeeekdedgflyvvyss 99 
                 krk+e+e+ir+ky driPvi+ek+ek++++++dkkkylvP+dltvgq+v++irkr++l+peka+f++v+e+lp+t+a ms++yee+kdedgfly++ys+
  EEA23028.1  13 KRKAEAERIRQKYADRIPVICEKVEKSDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTAALMSSIYEEHKDEDGFLYITYSG 111
                 79************************************************************************************************* PP

                 SSTB- CS
        Atg8 100 entfG 104
                 entfG
  EEA23028.1 112 ENTFG 116
                 ****9 PP

>> APG12  Ubiquitin-like autophagy protein Apg12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.0   4.1e-10   3.6e-06      10      87 .]      39     116 ..      28     116 .. 0.89

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 4.1e-10
                 TTS---S--EEEEETTSBHHHHHHHHHHHCT-.SSSS-EEEETTTB---TTSBHHHHHHHH-.BTTEEEEEEESSS--- CS
       APG12  10 gdvpilkkkklkvnasdtvakvilflkkeLklqaseslflYvnnsFaPsPdeeveeLyecfg.tdkklvlnYcisvAfG 87 
                 +d+  + kkk+ v a  tv +++  ++k++kl+ ++ +f++v++   P+    +  +ye ++  d+ l ++Y+ +  fG
  EEA23028.1  39 SDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTA-ALMSSIYEEHKdEDGFLYITYSGENTFG 116
                 5788899*************************************998875.6899*******4555566****999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (118 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       582  (0.0324614); expected 358.6 (0.02)
Passed bias filter:                      469  (0.0261587); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.31s 00:00:00.89 Elapsed: 00:00:00.54
# Mc/sec: 655.27
//
Query:       EEA23029.1  [L=118]
Description: autophagic death protein Aut7/IDI-7, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-51  172.1   0.2    3.2e-51  171.8   0.2    1.0  1  Atg8      Autophagy protein Atg8 ubiquitin like
      3e-06   27.5   0.0    3.6e-06   27.3   0.0    1.2  1  APG12     Ubiquitin-like autophagy protein Apg12


Domain annotation for each model (and alignments):
>> Atg8  Autophagy protein Atg8 ubiquitin like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  171.8   0.2   3.6e-55   3.2e-51       1     104 []      13     116 ..      13     116 .. 0.99

  Alignments for each domain:
  == domain 1  score: 171.8 bits;  conditional E-value: 3.6e-55
                 HHHHHHHHHHHHSTTEEEEEEEE-TTSSS---S-SEEEEETTSBHHHHHHHHHHHTT--TTS-EEEEETTE-SSTTSBHHHHHHHH--TTSSEEEEEES CS
        Atg8   1 krkkesekirekypdriPvivekaekeklpeldkkkylvPedltvgqlvliirkrlqlepekalfllvnetlpstsatmsalyeeekdedgflyvvyss 99 
                 krk+e+e+ir+ky driPvi+ek+ek++++++dkkkylvP+dltvgq+v++irkr++l+peka+f++v+e+lp+t+a ms++yee+kdedgfly++ys+
  EEA23029.1  13 KRKAEAERIRQKYADRIPVICEKVEKSDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTAALMSSIYEEHKDEDGFLYITYSG 111
                 79************************************************************************************************* PP

                 SSTB- CS
        Atg8 100 entfG 104
                 entfG
  EEA23029.1 112 ENTFG 116
                 ****9 PP

>> APG12  Ubiquitin-like autophagy protein Apg12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.3   0.0   4.1e-10   3.6e-06      10      87 .]      39     116 ..      28     116 .. 0.89

  Alignments for each domain:
  == domain 1  score: 27.3 bits;  conditional E-value: 4.1e-10
                 TTS---S--EEEEETTSBHHHHHHHHHHHCT-.SSSS-EEEETTTB---TTSBHHHHHHHH-.BTTEEEEEEESSS--- CS
       APG12  10 gdvpilkkkklkvnasdtvakvilflkkeLklqaseslflYvnnsFaPsPdeeveeLyecfg.tdkklvlnYcisvAfG 87 
                 +d+  + kkk+ v a  tv +++  ++k++kl+ ++ +f++v++   P+    +  +ye ++  d+ l ++Y+ +  fG
  EEA23029.1  39 SDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTA-ALMSSIYEEHKdEDGFLYITYSGENTFG 116
                 5788899*************************************998875.6899*******4555566****999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (118 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       582  (0.0324614); expected 358.6 (0.02)
Passed bias filter:                      469  (0.0261587); expected 358.6 (0.02)
Passed Vit filter:                        33  (0.00184059); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.35s 00:00:00.94 Elapsed: 00:00:00.56
# Mc/sec: 632.05
//
Query:       EEA23030.1  [L=1439]
Description: DNA-directed RNA polymerase III largest subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.2e-79  268.0   0.0    2.3e-79  267.0   0.0    1.5  1  RNA_pol_Rpb1_1  RNA polymerase Rpb1, domain 1
    8.1e-77  258.2   0.2    1.6e-76  257.3   0.2    1.5  1  RNA_pol_Rpb1_5  RNA polymerase Rpb1, domain 5
    5.8e-69  231.6   0.0    1.3e-68  230.5   0.0    1.6  1  RNA_pol_Rpb1_2  RNA polymerase Rpb1, domain 2
    2.1e-35  122.0   0.0    7.4e-35  120.2   0.0    2.0  2  RNA_pol_Rpb1_3  RNA polymerase Rpb1, domain 3
    9.2e-28   96.3   0.1    2.7e-27   94.8   0.1    1.9  1  RNA_pol_Rpb1_4  RNA polymerase Rpb1, domain 4
  ------ inclusion threshold ------
       0.82   10.0   2.4        2.7    8.3   1.1    2.5  2  Rpr2            RNAse P Rpr2/Rpp21/SNM1 subunit domain


Domain annotation for each model (and alignments):
>> RNA_pol_Rpb1_1  RNA polymerase Rpb1, domain 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  267.0   0.0   7.6e-83   2.3e-79       2     312 .]      20     367 ..      19     367 .. 0.93

  Alignments for each domain:
  == domain 1  score: 267.0 bits;  conditional E-value: 7.6e-83
                     E---EEEEEE--HHHHHHH-SBB--STTSTC.STSSSSBBSSSSSSSSS-SSSSSTSTTTSSTTTT-----EEEEEECEEE-HHHHHHHHHHCTT CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  RNA_pol_Rpb1_1   2 kkikeiqfgiaspeeirkwSvvevtkaetie.ekslkPeegGllDerlgtidkdleCetCgkkkkeCeghfGhieLakPvfhigffklilkilec 95 
                     k ike++fg +s++++ + +vve++ + +++ e+++  +e+G lD rlg + k  +C tCg  +k+C+ghfGh++L  P fhig+fk ++ il+ 
      EEA23030.1  20 KVIKELKFGALSDNDVISQAVVEISDRRFYDlERDRVVQENGPLDRRLGISGKMETCLTCGLGHKDCNGHFGHVKLVLPAFHIGYFKRVIGILQV 114
                     679****************************8888899********************************************************* PP

                     CETTTTEBSS-TTSH....HHHHHHCSSSCC..CCHHHHHHHHCCS-BE-SSSSB-EEE...........EEETTEEEEEESSSST......... CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxx...........xxxxxxxxxxxxxxxx......... RF
  RNA_pol_Rpb1_1  96 vckecskllldeekkkllsklkkrekleelk..krlkaieelckkinlcekCgavqpkl...........eeegeklkaalkkske......... 168
                     +ckecs +ll e +++ + k+ +r++l++l+  + +k++ e ckk ++c  Cgav++ +           +e++++++       +         
      EEA23030.1 115 ICKECSTILLPEAERRAFLKEMRRPRLDNLRrlQIAKRVVERCKKTRDCPRCGAVNGVVkkagtaalkivHEKFRHFN-------Qstsakkvpp 202
                     ******************************98899*******************888885555444433333333333.......2455566699 PP

                     .........................SCEEEE-HHHHHHHHHCSTHHHHHHTTSBTTTB-GGGCCECCEEE--GGGS-BEESSSSSEEBECCCCHH CS
                     .........................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  RNA_pol_Rpb1_1 169 .........................eekeklsaekvkkllkriededvevlgfkssgsrPewliltvlPVpPpeiRPsvqldggrrsedDltekl 238
                                              +++++l+a +v++l+k+i++ d+e+lg+++ + rPe ++++++P pP++iRPsv+ dg + +edDlt kl
      EEA23030.1 203 iskivfdnslaearasnpdvdrfykKAQDDLHALRVMNLFKKITNADCELLGLDPTEVRPETFLWQYIPAPPNCIRPSVSQDG-ASNEDDLTAKL 296
                     999999999***************9999*******************************************************.99********* PP

                     HHHHHHHHHHHHHHHSSSSSTCHHHHHHHHHHHHHHCC-TTSSSSSEEBSTTSSS--THHHHHTSSSSCCCCCT CS
                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  RNA_pol_Rpb1_1 239 rdiikrNnrLkkaeeegapeliieeekelLQehvatlfdneisglkpatqkskrplkslsqrLkGKeGrfRgnL 312
                      di++ N +L++++++gap  +++e ++ + +++a +++ +++g    + + ++p++sl +rLkGK+GrfRgnL
      EEA23030.1 297 GDIVQSNITLRNNLRKGAPVPTLMECWDYMTLQIAIYINGDVPG---LKGEAGKPTRSLVSRLKGKQGRFRGNL 367
                     ******************************************99...678***********************9 PP

>> RNA_pol_Rpb1_5  RNA polymerase Rpb1, domain 5
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  257.3   0.2   5.2e-80   1.6e-76       2     265 ..     856    1357 ..     855    1359 .. 0.95

  Alignments for each domain:
  == domain 1  score: 257.3 bits;  conditional E-value: 5.2e-80
                      --HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTEEEETTSEEEETTS-EEESSGGGTS............................ CS
                      xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx............................ RF
  RNA_pol_Rpb1_5    2 LkvkefffhtmggReGLiDtAvkTaesGYlqRrlvkaledvvvkyddtvrnsggeivqflygedg............................ 66  
                      L+++efffh+m gReGLiDtAvkTae+GY++Rrl+k+led+  kyd+t+r s+ +ivqf yg+d                             
      EEA23030.1  856 LSPTEFFFHAMSGREGLIDTAVKTAETGYMSRRLMKSLEDLSAKYDGTIRTSSASIVQFSYGGDDldpvdmegkakpvhfdrtynhamavthn 948 
                      89******************************************************************************************* PP

                      ............................................................................................. CS
                      ............................................................................................. RF
  RNA_pol_Rpb1_5   67 ............................................................................................. 66  
                                                                                                                   
      EEA23030.1  949 nnerglqpseiraiteellseerkryvrkglfgedlpykddsdygtdqlesarafldsiqehiekkavamekamdsalsdqearmaldhvgkl 1041
                      ********************************************************************************************* PP

                      ...................B--TT-BHHHHHHHHHHHHHHCCCSSTTSSTCSSTSSSSSSHHHHHHHHTT-SS-SS-EEEEEB-SSSSSCHHH CS
                      ...................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  RNA_pol_Rpb1_5   67 ...................lvepGeavGiiaaQSiGePgTQltlnTFHfaGvasknvtlGvprlkeilnvskniksksltvllvdeeakelek 140 
                                          +epG avG++ aQSiGePgTQ+tl+TFHfaGv++ + t+Gvpr+kei+n+sk+i+++ +t++l   +  el+ 
      EEA23030.1 1042 segslryfiksclfkyekaKIEPGHAVGAVGAQSIGEPGTQMTLKTFHFAGVGNLALTQGVPRIKEIINASKEISTPVITCHLAIPH--ELHA 1132
                      **********************************************************************************99888..8888 PP

                      CHHHHHHHSE................................................................................... CS
                      xxxxxxxxxx................................................................................... RF
  RNA_pol_Rpb1_5  141 akkvkkaiek................................................................................... 150 
                      a+++k++iek                                                                                   
      EEA23030.1 1133 ARIAKGRIEKtflrdiihyireswtdkegyitvklnwdtienlqlelslrqikdaitshrrfkgsdltvdvlrshikirvdmdpsskaglskt 1225
                      89999999999999******************************************************************************* PP

                      ..........................CBTTEEEEEEEEEEEEEEETEEEEEEECS--HHHHTTSTTTBETTTEEESSHHHHHHHHCHHHHHHH CS
                      ..........................xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  RNA_pol_Rpb1_5  151 ..........................gikkikrilvkeaekgkeeekelvletegvnlsevlkveevvdageilsndiaeileilgieaarka 217 
                                                g ++ +r+++ +++ g +     +l +eg  l++ +++++ v+  ++ +n++ e+  +lgieaar++
      EEA23030.1 1226 diaatsadpylrlkhlkrmlpdiqvlGHPQARRAIIHSER-GLN-----KLLVEGYGLRACMNTDG-VEGVRTKTNNVMEMRAVLGIEAARET 1311
                      ***********77777777776666666666666665332.322.....3579*************.************************** PP

                      HHHHHHHHHHHTTS---HHHHHHHHHHHTTTSS---SSTTCHCCSSSH CS
                      xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
  RNA_pol_Rpb1_5  218 llkeiqevykvqgvsvndrHlelivdqmtkkgeivavnrsGinkaels 265 
                      +++e+ ev+k   ++++ rH++l++d+mt++ge++ ++r G+ k+  s
      EEA23030.1 1312 IINEMGEVMKD--MDIDPRHMHLLADIMTTNGEVLGITRFGMAKMRDS 1357
                      ********986..788**************************998765 PP

>> RNA_pol_Rpb1_2  RNA polymerase Rpb1, domain 2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  230.5   0.0   4.2e-72   1.3e-68       1     166 []     369     538 ..     369     538 .. 0.97

  Alignments for each domain:
  == domain 1  score: 230.5 bits;  conditional E-value: 4.2e-72
                     SEEESSEEEEEEEEESSS-TTEEEEEHHHHTTSEEEEE-STTTHHHHHHHHHHTTTSSSSEEEE.ESTTSSEEETTTT-SC...HHCCTTTTSEE CS
  RNA_pol_Rpb1_2   1 GkrvdysaRsvispdpnlkldevgvPisvakkltvpeivtelnikklrklvengpevyPgasyv.kredgsekklkakkrk...lakelekgdiv 91 
                     Gkrvd+s+R+vispdpnl++dev+vP  vak++t+peivt++n + l+klv+ng +++Pga++v k+++g + +lk+  ++   ++k+l++gd v
      EEA23030.1 369 GKRVDFSGRTVISPDPNLRIDEVAVPELVAKNMTYPEIVTRYNLEYLQKLVRNGINKWPGAKKViKKDSGLTISLKHSAKSldtISKQLQIGDLV 463
                     9*************************************************************99788899999**999874455899******** PP

                     EEE--TTSEEEEE-SSTTSGGGEEEEEEEEESSSSEEEEGGGHCCCT--SSS-EEEEE--SSHHHHHHHHHCSBT CS
  RNA_pol_Rpb1_2  92 erhvkdgdvvllNRqPsLhklsimahrvkvlekktlrlnlsvttayNaDFDGDemnlhlpqseearaEaeelllv 166
                     erh+ dgd+ l NRqPsLhklsi +h vkv +++t+r+n++v+++yNaDFDGDemnlh+pq+eear+Ea el+ v
      EEA23030.1 464 ERHLVDGDIALYNRQPSLHKLSILSHFVKVRPYRTFRMNECVCNPYNADFDGDEMNLHIPQTEEARSEAMELMGV 538
                     ************************************************************************975 PP

>> RNA_pol_Rpb1_3  RNA polymerase Rpb1, domain 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  120.2   0.0   2.5e-38   7.4e-35       1     157 []     541     717 ..     541     717 .. 0.93
   2 ?   -2.8   0.0       1.8   5.3e+03      98     123 ..    1129    1154 ..    1122    1160 .. 0.79

  Alignments for each domain:
  == domain 1  score: 120.2 bits;  conditional E-value: 2.5e-38
                     CSEETTTTEESSS--THHHHHHHHHSSTTEEEEHHHHHHHHHHSSSCCSSSSSSSSSBESSSEBEEHHHHHHCCCHC......CCCEEEE.SSSS CS
  RNA_pol_Rpb1_3   1 nilspqsgkPvigivQDsllGvyllTkedvfidreeaqqllykgvgsdsktvtlrpailkpkelwtgkqtfsrilpn......einyerk.neek 88 
                     n+++p++g+P+ig +QD+++++y l+ +d f+dr  + q++ ++ g++++ ++++pailkp+  wtgkq+f  ++ +      ++n++   +  +
      EEA23030.1 541 NLVTPKNGEPIIGAIQDFISAAYVLSSKDNFFDRRSFTQICLYMLGPETRFDLPPPAILKPQMMWTGKQVFNILMRPnkddpvKVNIDAAcR--E 633
                     899************************************************************************99999999666665431..2 PP

                     ...............STSEEECSSEEEES--SHHHHSSSSTTSHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCEB-TGGGG CS
  RNA_pol_Rpb1_3  89 ...............dgkvlikngelikGvidkkvvgkksqgslihvlakeygiketvrfldslqrlgfkyllqsgftigigDt 157
                                    dg+ +i+n+e+++Gv+dk+++g+ ++ ++++++ +++g+ ++++ +++l++l+ +++++ gf+igi D+
      EEA23030.1 634 fkapkdgqpkdldpnDGWLVIRNSEIMCGVMDKSTIGSGKKDNVFYIMLRDFGPPAAAEGMNRLSKLCARWFTNVGFSIGITDV 717
                     23344788889***********************************************************************96 PP

  == domain 2  score: -2.8 bits;  conditional E-value: 1.8
                      EEEES--SHHHHSSSSTTSHHHHHHH CS
  RNA_pol_Rpb1_3   98 elikGvidkkvvgkksqgslihvlak 123 
                      el + +i k  ++k+ + ++ih++ +
      EEA23030.1 1129 ELHAARIAKGRIEKTFLRDIIHYIRE 1154
                      455778888889999999****9976 PP

>> RNA_pol_Rpb1_4  RNA polymerase Rpb1, domain 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   94.8   0.1   9.1e-31   2.7e-27       3     108 .]     744     848 ..     742     848 .. 0.96

  Alignments for each domain:
  == domain 1  score: 94.8 bits;  conditional E-value: 9.1e-31
                     HHCTHTCCHHHTTHCHHHHHHHHHHHHHHHHHHHHHHHHHHCSTTTSHHHHHHHCTSSS-HHHHHHHHTB-EEEEBTTBSS--SSTSCSSTTSSS CS
  RNA_pol_Rpb1_4   3 eaerygkledlpgksleelfeakinkilnkardkagkiaskslaasNsiliMvksGaKGsiinisqiagclGqqnvegkripkgfsgrtlphfkk 97 
                     +++  gkle+lpg    +++e++++ il+k+r++ag+ + k+l+++N  liM+ sG+KGs in+sq+++++Gqq ++++r+++gf++rtlphf k
      EEA23030.1 744 QYKA-GKLEKLPGCDELQTMESQVSGILSKVRQQAGEECIKQLSKYNAPLIMATSGSKGSSINVSQMVAVVGQQIISSERVQDGFQDRTLPHFPK 837
                     5566.9**************************************78************************************************* PP

                     SESSTTTSSEE CS
  RNA_pol_Rpb1_4  98 idespesrGFv 108
                     +   p s+GFv
      EEA23030.1 838 NARHPPSKGFV 848
                     **********8 PP

>> Rpr2  RNAse P Rpr2/Rpp21/SNM1 subunit domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   1.1   0.00091       2.7      45      87 ..     113     158 ..     109     167 .. 0.68
   2 ?   -1.3   0.0      0.93   2.8e+03      17      38 ..     882     903 ..     864     910 .. 0.81

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00091
                 CTB-TTT--B--CTTTEEEEEE-SSS-E............EEEEET CS
        Rpr2  45 rtvCkkCgsvlipgvtcsvrvenkskkkkkkkkka...dvlvvtCl 87 
                 + +Ck+C+++l+p+ + +  +++ ++++  + ++    +++v +C+
  EEA23030.1 113 QVICKECSTILLPEAERRAFLKEMRRPRLDNLRRLqiaKRVVERCK 158
                 569*****************98877765433333256644444443 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 0.93
                 -HHHHHHHHHHHHHHHHHCT-- CS
        Rpr2  17 spalsrylakqlrevskkaqlr 38 
                 +  +sr+l+k+l+++s k+   
  EEA23030.1 882 TGYMSRRLMKSLEDLSAKYDGT 903
                 55689***********998765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1439 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       579  (0.032294); expected 358.6 (0.02)
Passed bias filter:                      524  (0.0292264); expected 358.6 (0.02)
Passed Vit filter:                        52  (0.00290033); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 1.05u 0.37s 00:00:01.42 Elapsed: 00:00:00.57
# Mc/sec: 7607.00
//
Query:       EEA23031.1  [L=512]
Description: tRNA-specific adenosine-34 deaminase subunit Tad3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.3e-06   26.2   0.1    6.4e-05   22.8   0.1    2.3  1  dCMP_cyt_deam_1  Cytidine and deoxycytidylate deaminase zinc-
     0.0016   18.2   0.0       0.13   12.0   0.0    2.3  2  MafB19-deam      MafB19-like deaminase
  ------ inclusion threshold ------
       0.77   10.1   5.2          4    7.8   0.1    2.8  3  TYA              TYA transposon protein


Domain annotation for each model (and alignments):
>> dCMP_cyt_deam_1  Cytidine and deoxycytidylate deaminase zinc-binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.8   0.1   1.1e-08   6.4e-05       6      97 ..     221     413 ..     217     416 .. 0.84

  Alignments for each domain:
  == domain 1  score: 22.8 bits;  conditional E-value: 1.1e-08
                      HHHHHHHHHHHHHH.TTTSCSEEEEEEETTEEEEEEESBHHCCTG........................................TTB-HHHHH CS
  dCMP_cyt_deam_1   6 kllelalkaakeaq.kcsnfkVGavivkngeiistgyngepaggs........................................ktiHAEvnA 58 
                      ++l+la ++a+ea+ +     +G viv+     s   ng     +                                        ++ HA + A
       EEA23031.1 221 YYLSLAGQVAREAKgAGRGRGIGVVIVDPAIAASSRSNGATLTEDdeegdngvvavagdarycapglasrdnlgegvyeadceggPEFHAIMRA 314
                      7889999999999999999999999999756666666666655558899999999999999999999999999999999999999899999999 PP

                      HHHHHHHT.SSCE...........................................................TTEEEEEEE--BHHHHHHHHHH CS
  dCMP_cyt_deam_1  59 ilkaakng.gskl...........................................................egatlyvtlePCsmCakaiiqs 92 
                      +  +a+++   k+                                                           ++  +y+t+ePC  C++ +  s
       EEA23031.1 315 VEMVATRRrDDKVamatdktasirntsltpleshylcrpaspsqytsitetdthtnqnagrilsraaggylcTDLDIYITHEPCLACSMGMLLS 408
                      998888843555588999999999999999999999999999999999999999999999999999999999*****************99998 PP

                      T-SEE CS
  dCMP_cyt_deam_1  93 gikkv 97 
                      + + +
       EEA23031.1 409 RFRAI 413
                      88766 PP

>> MafB19-deam  MafB19-like deaminase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    3.9   0.0     0.007        42      54      77 ..     307     330 ..     270     337 .. 0.88
   2 !   12.0   0.0   2.2e-05      0.13      68     122 ..     384     441 ..     363     455 .. 0.77

  Alignments for each domain:
  == domain 1  score: 3.9 bits;  conditional E-value: 0.007
  MafB19-deam  54 EiaalqqAakklkskrlddatlyv 77 
                  E +a+++A++ +++ r dd +   
   EEA23031.1 307 EFHAIMRAVEMVATRRRDDKVAMA 330
                  88*************999977655 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 2.2e-05
  MafB19-deam  68 krlddatlyvtlepCdmCagaivqaglkklvygagnpks......lnkLkvkekngrvelv 122
                      d+ +y+t+epC  C   +  ++ + + +      +      l ++++ +++ r +l+
   EEA23031.1 384 YLCTDLDIYITHEPCLACSMGMLLSRFRAITFPRR---GrlvtggLASMEIPQSSSRAKLE 441
                  5567899***********99999999999987665...22346679999999999998877 PP

>> TYA  TYA transposon protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.8   0.1   0.00067         4      29      66 ..      82     119 ..      74     123 .. 0.91
   2 ?    3.5   0.5     0.015        88      35      70 ..     176     211 ..     172     220 .. 0.87
   3 ?   -3.1   0.0       1.8     1e+04       2      15 ..     359     372 ..     358     376 .. 0.83

  Alignments for each domain:
  == domain 1  score: 7.8 bits;  conditional E-value: 0.00067
         TYA  29 kastkansqqettpassavpenhhhaspqaaqvpspqn 66 
                    t+++ ++e tp+ +av e+   +  +++q+p+pq 
  EEA23031.1  82 AIKTQIDNEKEKTPLPTAVTEDGAEIENESTQTPPPQV 119
                 56799*******************************95 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.015
         TYA  35 nsqqettpassavpenhhhaspqaaqvpspqnGpyq 70 
                 nsqq  t +    p n   asp+   +p+p+  +  
  EEA23031.1 176 NSQQAETWSKIYWPTNFNAASPRGMIAPPPKILNVT 211
                 9***********************999999865555 PP

  == domain 3  score: -3.1 bits;  conditional E-value: 1.8
         TYA   2 casvtskevqtnqd 15 
                 ++s+t  + +tnq+
  EEA23031.1 359 YTSITETDTHTNQN 372
                 78999999999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (512 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       425  (0.0237046); expected 358.6 (0.02)
Passed bias filter:                      380  (0.0211947); expected 358.6 (0.02)
Passed Vit filter:                        26  (0.00145016); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.69u 0.33s 00:00:01.02 Elapsed: 00:00:00.54
# Mc/sec: 2870.39
//
Query:       EEA23032.1  [L=446]
Description: cyclin-dependent protein kinase regulator Pho80 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-31  109.6   0.8    1.9e-31  109.6   0.8    2.5  2  Cyclin    Cyclin
    0.00014   21.6   0.0    0.00023   20.9   0.0    1.3  1  Cyclin_N  Cyclin, N-terminal domain


Domain annotation for each model (and alignments):
>> Cyclin  Cyclin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.1   0.2      0.99   8.9e+03      40      62 ..      43      75 ..      18      76 .. 0.54
   2 !  109.6   0.8   2.1e-35   1.9e-31      48     161 .]     287     398 ..     153     398 .. 0.74

  Alignments for each domain:
  == domain 1  score: -3.1 bits;  conditional E-value: 0.99
                ..........................T--SS-- CS
      Cyclin 40 s..........shtkttfaqtpkessFatkavp 62
                s          s    +fa ++++s +++++ p
  EEA23032.1 43 SpnhfsapgatSASAAQFAASSRVSPYSGFNSP 75
                233333445546666667777777777776655 PP

  == domain 2  score: 109.6 bits;  conditional E-value: 2.1e-35
                 ........T--SS--SS-HHHHHHHHHHHTT--HHHHHHHHHHHHHHHH..H-TT---STTTHHHHHHHHHHHHHHHH-SS---HHHHHHHHTS-HHHH CS
      Cyclin  48 aqtpkessFatkavpaisigsylsrlqkfgesaplvllgtliYldrivkrcvsealvvtsanihRllivallvatKflvDlsysnekfakvggislkEL 146
                  q  +   F+++ +p is+++yl+rl+ ++ ++p +ll++++Y+dr+    ++ a++v s+++hR+li++ +va+K l+D++ +n+ +a+vggi ++EL
  EEA23032.1 287 LQGGRLTRFHSRTPPRISVRDYLQRLTTHATLSPPILLSMVYYIDRLCA--LYPAFTVSSLTVHRFLITSATVASKGLSDSFWTNKTYARVGGITITEL 383
                 44455667888888***********************************..************************************************ PP

                 HHHHHHHHHHTTT-- CS
      Cyclin 147 nkLEidFlflvdFdl 161
                 + LE+dFl +v++++
  EEA23032.1 384 AMLELDFLWRVEWKI 398
                 **********99875 PP

>> Cyclin_N  Cyclin, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.0   2.6e-08   0.00023      31     126 ..     302     398 ..     291     399 .. 0.89

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 2.6e-08
                 HHHHHHHHHHHHHHTT--TTHHHHHHHHHHHHHHHS...---CCCHHHHHHHHHHHHHHHHSSS---HHHHHHHTTTSS-HHHHHHHHHHHHHHTTT-- CS
    Cyclin_N  31 RailidwlvevaekfkltpetlflavnyldRflskk...svpkdklqlvgatcLllAaKveeisppkledlvyitdeafteeeilemErliLetLnfdl 126
                 R ++ d+l +++++  l+p +l+  v y+dR+++      v+  ++++  +t+  +A+K   +s  + + ++ +  + +t +e+  +E+++L   ++++
  EEA23032.1 302 RISVRDYLQRLTTHATLSPPILLSMVYYIDRLCALYpafTVSSLTVHRFLITSATVASKGLSDSFWTNKTYARV--GGITITELAMLELDFLWRVEWKI 398
                 78889*****************************5432356666*******************99999999999..56999999999*****9999997 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (446 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       585  (0.0326287); expected 358.6 (0.02)
Passed bias filter:                      289  (0.0161191); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.69u 0.32s 00:00:01.01 Elapsed: 00:00:00.54
# Mc/sec: 2468.71
//
Query:       EEA23033.1  [L=979]
Description: armadillo repeat protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.3e-18   64.7   4.8    3.6e-06   26.8   0.0    9.6 10  Arm       Armadillo/beta-catenin-like repeat
     0.0051   16.9   5.1        1.8    9.0   0.0    6.0  6  HEAT      HEAT repeat
  ------ inclusion threshold ------
      0.064   13.3   1.5        2.5    8.1   0.1    3.1  3  Cnd1      non-SMC mitotic condensation complex subunit 1


Domain annotation for each model (and alignments):
>> Arm  Armadillo/beta-catenin-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.1      0.21   1.3e+03      19      36 ..      11      28 ..       7      30 .. 0.86
   2 !    4.0   0.0    0.0095        57       5      24 ..      39      58 ..      35      62 .. 0.81
   3 ?   -0.8   0.0      0.29   1.8e+03      27      40 ..     134     147 ..     107     148 .. 0.68
   4 ?   -0.7   0.0      0.28   1.7e+03       4      17 ..     209     222 ..     206     223 .. 0.89
   5 ?    0.3   0.0      0.14   8.3e+02       3      22 ..     470     489 ..     468     497 .. 0.78
   6 ?    3.6   0.0     0.013        75       2      22 ..     553     573 ..     552     585 .. 0.80
   7 !   15.0   0.1   3.1e-06     0.019       7      40 ..     619     652 ..     614     653 .. 0.93
   8 !   26.8   0.0     6e-10   3.6e-06       2      40 ..     656     694 ..     655     695 .. 0.95
   9 ?    2.9   0.0     0.021   1.3e+02      23      39 ..     799     815 ..     795     816 .. 0.88
  10 ?   -0.3   0.0      0.21   1.3e+03      17      40 ..     901     924 ..     898     925 .. 0.86

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.21
                HHTTTSSHHHHHHHHHHH CS
         Arm 19 rLLssedeevqeeAawAL 36
                rLL+s++++ q++A++AL
  EEA23033.1 11 RLLNSTSVSEQTAALRAL 28
                7999************99 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.0095
                HHHHHHTTHHHHHHHHTTTS CS
         Arm  5 kdavieaGavppLvrLLsse 24
                k+  +++G+vp+L r L++ 
  EEA23033.1 39 KERWVSSGIVPILSRILECL 58
                677899*********99964 PP

  == domain 3  score: -0.8 bits;  conditional E-value: 0.29
                 HHHHHHHHHHHHHT CS
         Arm  27 evqeeAawALsNLa 40 
                 +++ +++ +LsN+a
  EEA23033.1 134 SLTVAILKTLSNIA 147
                 55667778899988 PP

  == domain 4  score: -0.7 bits;  conditional E-value: 0.28
                 HHHHHHHTTHHHHH CS
         Arm   4 nkdavieaGavppL 17 
                 +k a+ e+G++++L
  EEA23033.1 209 HKAALAEYGVLDAL 222
                 58899*******99 PP

  == domain 5  score: 0.3 bits;  conditional E-value: 0.14
                 HHHHHHHHTTHHHHHHHHTT CS
         Arm   3 enkdavieaGavppLvrLLs 22 
                 e  ++ +ea a+++L +LL+
  EEA23033.1 470 ELQKHAVEATAIKILSQLLK 489
                 6677889999*********9 PP

  == domain 6  score: 3.6 bits;  conditional E-value: 0.013
                 HHHHHHHHHTTHHHHHHHHTT CS
         Arm   2 senkdavieaGavppLvrLLs 22 
                 +e ++a++e G+vp  ++ L+
  EEA23033.1 553 DEYRKAICENGVVPYIIDSLK 573
                 6899**********9888776 PP

  == domain 7  score: 15.0 bits;  conditional E-value: 3.1e-06
                 HHHHTTHHHHHHHHTTTSSHHHHHHHHHHHHHHT CS
         Arm   7 avieaGavppLvrLLssedeevqeeAawALsNLa 40 
                  +i+aG+  pL +L+++ d evq +A++ ++N+a
  EEA23033.1 619 SLIDAGVATPLFELIKHRDIEVQIAATSVICNIA 652
                 589******************************8 PP

  == domain 8  score: 26.8 bits;  conditional E-value: 6e-10
                 HHHHHHHHHTTHHHHHHHHTTTSSHHHHHHHHHHHHHHT CS
         Arm   2 senkdavieaGavppLvrLLssedeevqeeAawALsNLa 40 
                 s+ k+a+i+aG++p+L++  +s +++++ e++wAL ++a
  EEA23033.1 656 SPMKEAIISAGILPILCDHAHSNNTKLRLESLWALKHIA 694
                 6789*******************************9998 PP

  == domain 9  score: 2.9 bits;  conditional E-value: 0.021
                 TSSHHHHHHHHHHHHHH CS
         Arm  23 sedeevqeeAawALsNL 39 
                  +d  vqe+A+  ++N+
  EEA23033.1 799 QDDIAVQEQALDLVRNI 815
                 57999***********9 PP

  == domain 10  score: -0.3 bits;  conditional E-value: 0.21
                 HHHHTTTSSHHHHHHHHHHHHHHT CS
         Arm  17 LvrLLssedeevqeeAawALsNLa 40 
                 L+ L ++++  v+ +++w + NL+
  EEA23033.1 901 LMWLFEHPNRVVRVNCVWVVINLT 924
                 78888999999*******987775 PP

>> HEAT  HEAT repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.1      0.68   4.1e+03       3      17 ..     423     436 ..     421     438 .. 0.79
   2 ?   -3.2   0.1       2.6   1.6e+04      17      29 ..     538     550 ..     536     551 .. 0.78
   3 ?    2.4   0.0     0.041   2.5e+02       5      28 ..     629     652 ..     627     654 .. 0.91
   4 !    9.0   0.0   0.00031       1.8       1      29 [.     667     695 ..     667     697 .. 0.95
   5 ?    1.2   0.0       0.1   6.1e+02      10      27 ..     906     923 ..     901     925 .. 0.83
   6 ?   -1.3   0.0      0.63   3.8e+03      10      27 ..     956     973 ..     948     973 .. 0.80

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 0.68
                 HHHHHHHT-SSHHHH CS
        HEAT   3 PlllkllsDpspeVR 17 
                 Plll++l D++ + R
  EEA23033.1 423 PLLLRML-DKDYDFR 436
                 99***98.8887666 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 2.6
                 HHHHHHHHHHHHH CS
        HEAT  17 ReaAakaLgalae 29 
                 Re  ++aL+ala+
  EEA23033.1 538 REGILRALAALAP 550
                 6667899999986 PP

  == domain 3  score: 2.4 bits;  conditional E-value: 0.041
                 HHHHHT-SSHHHHHHHHHHHHHHH CS
        HEAT   5 llkllsDpspeVReaAakaLgala 28 
                 l +l+++ + eV  aA   ++++a
  EEA23033.1 629 LFELIKHRDIEVQIAATSVICNIA 652
                 78999****************997 PP

  == domain 4  score: 9.0 bits;  conditional E-value: 0.00031
                 HHHHHHHHHT-SSHHHHHHHHHHHHHHHH CS
        HEAT   1 llPlllkllsDpspeVReaAakaLgalae 29 
                 +lP+l+   ++++ + R  +++aL ++a 
  EEA23033.1 667 ILPILCDHAHSNNTKLRLESLWALKHIAY 695
                 89************************996 PP

  == domain 5  score: 1.2 bits;  conditional E-value: 0.1
                 T-SSHHHHHHHHHHHHHH CS
        HEAT  10 sDpspeVReaAakaLgal 27 
                 ++p+  VR ++++ + +l
  EEA23033.1 906 EHPNRVVRVNCVWVVINL 923
                 8999*********98776 PP

  == domain 6  score: -1.3 bits;  conditional E-value: 0.63
                 T-SSHHHHHHHHHHHHHH CS
        HEAT  10 sDpspeVReaAakaLgal 27 
                 +D++ +VRe +  aL ++
  EEA23033.1 956 EDSDLDVRERTKTALHQI 973
                 799******988888776 PP

>> Cnd1  non-SMC mitotic condensation complex subunit 1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0      0.77   4.6e+03      84     105 ..     467     488 ..     451     499 .. 0.44
   2 ?    2.5   0.0     0.022   1.3e+02      12      96 ..     615     704 ..     605     716 .. 0.63
   3 ?    8.1   0.1   0.00042       2.5      24      87 ..     899     975 ..     894     978 .. 0.75

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.77
        Cnd1  84 eiseksenaiynllpdiiskls 105
                 + +e ++ a+    ++i+s+l+
  EEA23033.1 467 DTQELQKHAVEATAIKILSQLL 488
                 3333333333333333333333 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.022
        Cnd1  12 cirvpnlveylvepLrkrLkDedpyVRktaaivvakL.....ilndmvkekgflselaklleDenprVvanalaalteiseksenaiynl 96 
                 ++r + +   + +pL + +k +d  V+  a  v++++       ++ +++ g+l  l +  + +n++ +  +l al+ i+ +s+n i n 
  EEA23033.1 615 VLRTSLIDAGVATPLFELIKHRDIEVQIAATSVICNIaldfsPMKEAIISAGILPILCDHAHSNNTKLRLESLWALKHIAYNSTNDIKNK 704
                 444444444567889999998888888877777777763543344566666666666666666666666666666666666665555544 PP

  == domain 3  score: 8.1 bits;  conditional E-value: 0.00042
        Cnd1  24 epLrkrLkDedpyVRktaaivvakL...........ilndm.....vkekgflselaklleDenprVvanalaalteise 87 
                 ++L   ++ ++  VR +++ vv++L               +      k+ g++++l++  eD++  V++ +++al++i +
  EEA23033.1 899 KNLMWLFEHPNRVVRVNCVWVVINLtyeddqsdrqaS---YeravkLKSLGVIDRLRSVEEDSDLDVRERTKTALHQIRK 975
                 5566666778999************865555444431...03332355667**************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (979 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       432  (0.024095); expected 358.6 (0.02)
Passed bias filter:                      399  (0.0222544); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.85u 0.35s 00:00:01.20 Elapsed: 00:00:00.55
# Mc/sec: 5337.61
//
Query:       EEA23034.1  [L=166]
Description: fructosamine-3-kinase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    9.9e-43  146.4   0.0    1.1e-42  146.2   0.0    1.0  1  Fructosamin_kin  Fructosamine kinase


Domain annotation for each model (and alignments):
>> Fructosamin_kin  Fructosamine kinase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  146.2   0.0   6.2e-47   1.1e-42     155     287 ..       1     161 [.       1     162 [. 0.96

  Alignments for each domain:
  == domain 1  score: 146.2 bits;  conditional E-value: 6.2e-47
  Fructosamin_kin 155 vqlelakekglefakieelvervaell................skhqpkpsllHGdLWsgNaaltkdge.........pvifdPaayygdrEvd 223
                      ++l+ +++k++++a +++lv ++ae++                +++ + p+++HGdLWsgNa+ +++ +          +++dP+a+y+++E++
       EEA23034.1   1 MILKESERKNGSDAGLRDLVTKTAEKVvprllgddhlgydrngQGEGIYPVVVHGDLWSGNASHGRIVRsssteneggGLVYDPSACYAHNEYE 94 
                      689999*********************************************************9998444789999999*************** PP

  Fructosamin_kin 224 lamtelfggfpsefyegYqsivpld...egyeeRkelYqLYhlLnhlnlFgggylsqaqkliqkllk 287
                      l+++++fggf+++f++ Y+sivp +   e+ye+R++lY+LYh+Lnh+++Fgggy+s a +++++l++
       EEA23034.1  95 LGIMHMFGGFGKAFFDEYHSIVPRTepvEEYEDRVKLYELYHHLNHHAIFGGGYRSGAVSIMSELID 161
                      ************************99999**********************************9986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (166 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       338  (0.0188521); expected 358.6 (0.02)
Passed bias filter:                      314  (0.0175135); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.58u 0.33s 00:00:00.90 Elapsed: 00:00:00.54
# Mc/sec: 927.15
//
Query:       EEA23035.1  [L=392]
Description: cyclin, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.1e-08   33.9   0.1    4.6e-07   29.6   0.0    2.2  2  Cyclin_N  Cyclin, N-terminal domain


Domain annotation for each model (and alignments):
>> Cyclin_N  Cyclin, N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.6   0.0   2.6e-11   4.6e-07      21     123 ..      31     148 ..      17     152 .. 0.83
   2 !    2.2   0.0     0.008   1.4e+02      66      90 ..     190     214 ..     154     246 .. 0.71

  Alignments for each domain:
  == domain 1  score: 29.6 bits;  conditional E-value: 2.6e-11
                 TCTSSS-HHHHHHHHHHHHHHHHHTT--TTHHHHHHHHHHHHHHHS---CCCHHHHHHHHHHHHHHHHSSS---HHHHHHHT.............TT.. CS
    Cyclin_N  21 dqqpelnpemRailidwlvevaekfkltpetlflavnyldRflskksvpkdklqlvgatcLllAaKveeisppkledlvyit.............de.. 104
                 +  p+ +++ R + ++w+ +v + ++l  +t  +a +y+++f   +  +++     +a++L+ A+K+e++   k +d+v+++             d+  
  EEA23035.1  31 EVDPQREDDIRISGVTWIDNVRKALRLPVRTYNTACVYYHKFRLVHPDSQYSYMDAAAAALFTACKIEDT-LKKSRDIVCAAynlklppseqvssDDai 128
                 5566666799**********************************9999999999*************888.8999999999988888888888874444 PP

                 .SS-HHHHHHHHHHHHHHTT CS
    Cyclin_N 105 .afteeeilemErliLetLn 123
                  +   + ++ +Erl+Le+  
  EEA23035.1 129 fDQHSRGVIILERLMLEASG 148
                 55556678888888887655 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.008
                 S---CCCHHHHHHHHHHHHHHHHSS CS
    Cyclin_N  66 ksvpkdklqlvgatcLllAaKveei 90 
                     k++  +++ +cL lA+++ ++
  EEA23035.1 190 FAPLKQTTGTMAFACLELASRLLNA 214
                 44567778899*********98665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (392 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       436  (0.0243181); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.32s 00:00:01.00 Elapsed: 00:00:00.55
# Mc/sec: 2128.00
//
Query:       EEA23036.1  [L=442]
Description: phosphatidate cytidylyltransferase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    4.9e-80  269.1  25.2      6e-80  268.8  25.2    1.1  1  CTP_transf_1  Cytidylyltransferase family


Domain annotation for each model (and alignments):
>> CTP_transf_1  Cytidylyltransferase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  268.8  25.2   3.4e-84     6e-80       2     266 .]      60     386 ..      59     386 .. 0.99

  Alignments for each domain:
  == domain 1  score: 268.8 bits;  conditional E-value: 3.4e-84
                   HHHHHHHHHHHHHHHTTTSH.HHHHHHHHHHHHHHHHHHHHTT--SHHHHHHHHH....HHHHHHHHHHTTTSSSHHHHHHHHHHHHHHHHHH---. CS
  CTP_transf_1   2 qRvitalvlilivliilllgglvflllvavvvilalkElirlvrlkkrekrllll.llslvlllllllflylesliallklvlllvlvllllvlkvl 97 
                   +R+i+++v+i+ ++ +++ g+++++++v++v+i+ +kE+i+++++ ++ ++l ++  l++++l ++++fly+es+i ++k++ll++ +ll +++   
    EEA23036.1  60 TRTIWTFVMIAGFFSAMFSGHIYLIAIVTAVQIISFKEVIAIANVPSKGRNLRFTkSLNWYFLATTMYFLYGESVIYYFKHILLVDRILLPFAT--- 153
                   7***************************************************************************************999988... PP

                   ..HHHHHHHHHHHHHHHHHTHHHH............................TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH---B-S-TT CS
  CTP_transf_1  98 kskskklervilallallyvvlll...........................qslllienikeglllvllllalvvaaDigaYffGklfGktkllpki 167
                         ++r+++++l+++++v+++                           q++++++ni+eg+++++l+ +lv+++Di+aY++G++fG+t  l+k+
    EEA23036.1 154 ------HHRFLSFMLYVFGFVFFVatlqkghyrfqftqfawthmalylivvQAHFIMNNIFEGMIWFFLPASLVITNDIFAYVCGITFGRT-QLIKL 243
                   ......8************************************************************************************.***** PP

                   S---BHHHHHHHHHHHHHHHHHHHHHHHCTS............................................---TTSHHHHHHHHHHHHHHHH CS
  CTP_transf_1 168 SPkKTveGfigGlvaavvvglllalvlskal............................................alsllhllllslllslvavfGD 220
                   SPkKTveGfig++++++++g++++++l++++                                            a++++h+l++++++sl+a+fG+
    EEA23036.1 244 SPKKTVEGFIGAWICTIIFGYFMTNILMQYKyficpvtdlgsnvvtglectvnpvfipttyhlpdwpllpttirvAPMQFHILVFATFASLIAPFGG 340
                   *****************************99****************************************************************** PP

                   HHHHHHHHHHT-SSS-S-SSSSS-HHHHHHHHHHHHHHHHHHHHHH CS
  CTP_transf_1 221 LveSglKRafgiKDsGkliPGhGGilDRlDsllfaapvvylllelf 266
                   +++SglKR+f+iKD+G++iPGhGGi+DR+D++++++ ++++++++f
    EEA23036.1 341 FFASGLKRTFKIKDFGESIPGHGGITDRMDCQFIMGFFAFMYYQSF 386
                   *******************************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (442 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       745  (0.0415528); expected 358.6 (0.02)
Passed bias filter:                      281  (0.0156729); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.68u 0.32s 00:00:01.00 Elapsed: 00:00:00.54
# Mc/sec: 2462.21
//
Query:       EEA23037.1  [L=748]
Description: DNA repair protein Rad26, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.5e-41  141.7   0.4    2.9e-41  140.8   0.4    1.5  1  DUF3636     Protein of unknown function (DUF3636)
    1.6e-05   23.6   5.6      0.012   14.2   0.2    2.7  3  LCD1        DNA damage checkpoint protein
     0.0039   16.7   5.0     0.0058   16.2   5.0    1.2  1  HMMR_N      Hyaluronan mediated motility receptor N-terminal
  ------ inclusion threshold ------
      0.049   14.1   2.6        0.1   13.0   2.6    1.5  1  Fez1        Fez1
       0.13   12.6   7.5        0.5   10.8   7.5    1.9  1  CC2-LZ      Leucine zipper of domain CC2 of NEMO, NF-kappa-B 
        0.2   11.8   1.0        3.3    7.9   0.2    2.6  2  YfhD        YfhD-like protein
       0.23   11.5   7.4      0.092   12.8   3.7    2.1  2  TPR_MLP1_2  TPR/MLP1/MLP2-like protein
       0.25    9.2   4.3       0.36    8.7   4.3    1.1  1  V_ATPase_I  V-type ATPase 116kDa subunit family
        0.3   11.7   3.6       0.63   10.7   2.6    2.1  2  YabA        Initiation control protein YabA


Domain annotation for each model (and alignments):
>> DUF3636  Protein of unknown function (DUF3636)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.8   0.4   1.4e-44   2.9e-41       1     148 []     480     633 ..     480     633 .. 0.98

  Alignments for each domain:
  == domain 1  score: 140.8 bits;  conditional E-value: 1.4e-44
                 -HHHHHHHHHHHHHHHS-----HHHHHHSS-HHHHHHHTSTTS-HHHHHHHHHHGGGG--SS-SS----HHHHHHHHHHHHHHHHHHHHHS--T....T CS
     DUF3636   1 dvtecLelLylaAlgclssseaierFWrlieldfvllmLskkqplediilmLelLstSvlpdsfGpisseeedqkavekaiidrvsnlLteepradege 99 
                 d+t +Le++yl+Al+c +++e++e++Wr+i++d+ l++L+ +qpl+di+l L++LstS +++sfG+i  +ee+q++ve + i+rv++lL++++++dege
  EEA23037.1 480 DSTFALEIMYLLALACRQDDESHEHLWRNIHFDILLMTLNDHQPLQDIVLSLKILSTSLRQNSFGTILPTEEEQRQVEFHFIERVTCLLFQRIEPDEGE 578
                 78999********************************************************************************************** PP

                 S-TTSHHHHHHHHHHHHHHHHHHHSH......HHHHHHHH-SSHHHHHHHHHHHH CS
     DUF3636 100 akvteaeilelrleaLrvLtafarsp......fgslalashdsaigRlvrvLsde 148
                 + + + +i+++rleaL++L+++++++       +++a++s +++++Rl+r+L+de
  EEA23037.1 579 EDYLPLQICQMRLEALTFLEMITFYSfdmmadASKTAIISYPLVLPRLFRTLYDE 633
                 **************************999999999*****************986 PP

>> LCD1  DNA damage checkpoint protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.2     6e-06     0.012       1     140 [.     169     364 ..     169     387 .. 0.76
   2 ?   -0.7   0.0      0.19   3.7e+02     444     527 ..     604     695 ..     582     701 .. 0.67
   3 !   11.0   0.6   5.4e-05      0.11     580     613 .]     698     732 ..     687     732 .. 0.89

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 6e-06
                 HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHTTTTTT.HHHH------TT---SSS--................ CS
        LCD1   1 mLrdkLelLeqekekeleklknskkqlkesheeelekLkkevqkleDekkFlenElrslset.ksqaskksaeedtdnsssvs................ 82 
                 +Lr+ L+   +e e+ +++l+ + ++l  +++   ++  ++ qkle+e++Fl  Elr+ +   ++ ++kk +e  ++  ++ +                
  EEA23037.1 169 ILRANLTKQAKEFERTIASLRTQLTDLTTKNKGVQQAAIDDRQKLETENLFLREELRDETLRvNNLRAKKRTEAPQTPRKQRTlpfrdgfdddeigvls 267
                 789999998999999999999999999999999888888999****************99864355555555555555555556899************ PP

                 ..................THHHHHHHHH................HHHTSTTT--................TTHHHHHHHHH---SSSTTTTTTTTSS-- CS
        LCD1  83 ..................kKkRKieestaeda..slsls.....lkkkviklqk................etslffdslllhkilGsdlttleiLskik 140
                                   k kRK++++    a  +  ls     +  +++ l++                e+  ++ ++l+h+ +  + + le++  + 
  EEA23037.1 268 ptkssggrskrgtptvsgKRKRKVSDAPIPMAplQ--LSqeigaMDAETLALNSmdtvaderqhvpgegiEEGFYMTQILNHRNHPNSESDLEVMAGLA 364
                 ****************9999999999876666551..33445566666666666666666667788888888888888888887766666666666555 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.19
                 H.......TT-SHHHHTTHHHHHHHHHHHHHHHHHHTS--TTHHHHHHHHHHHHHHHHHHHHHT.-S------..-TTTHHHHHHHHHHHHGGG CS
        LCD1 444 k.......keisklinkellksllrliskeQelllsgqrsknldlrielieslvkliyylwiqe.seelseei..ikeleselvvaLsriafgs 527
                 +       +++ ++  + +l  l+r++  e + l +    +   +r  li+ l+ li +l+ +   ++l e    ++ ++++  ++Lsr af++
  EEA23037.1 604 SfdmmadaSKTAIISYPLVLPRLFRTLYDEMDRLYT--LCPEHSIRTALINRLMHLIFKLIRSGgGKDLHEGLsrLSGTKQKHRLVLSRLAFSE 695
                 344444445566666677777777777777777777..66677899999999999999999543235555554556677777777889999986 PP

  == domain 3  score: 11.0 bits;  conditional E-value: 5.4e-05
                 HH-------HHHHHHHTTTT.---HHHHHHHHH-X CS
        LCD1 580 glevkyeeetvelAreiLes.cvslEeaDnLYlnm 613
                  le    eet+e+Ar++Le   +s+Eea++L+ ++
  EEA23037.1 698 FLESGITEETMEMARQLLEEeDMSPEEAEALFDAF 732
                 57788899***********99**********9876 PP

>> HMMR_N  Hyaluronan mediated motility receptor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   5.0   2.9e-06    0.0058     231     325 ..     134     228 ..     114     238 .. 0.86

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 2.9e-06
      HMMR_N 231 eyieelsnvseqlekykldiaqleellkekndeiesLkssLeekeqelskqvkdlnekckllekekeelvreeeekeqtlsaEleelkeklklke 325
                 e  +++++ s+q +  ++++a ++e + +k+ e+ +L+ +L ++++e+++++ +l +++  l ++++ + + +   +q+l++E   l+e+l+ + 
  EEA23037.1 134 EIGARIEEFSRQYDAINEQLALAREDATKKAGEVAILRANLTKQAKEFERTIASLRTQLTDLTTKNKGVQQAAIDDRQKLETENLFLREELRDET 228
                 5557888899999999***********************************************99998888888899999999988999887765 PP

>> Fez1  Fez1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   2.6   5.3e-05       0.1      17     113 ..     151     248 ..     147     328 .. 0.76

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 5.3e-05
        Fez1  17 qQLkdsqaevtqklseivalkaqlrelrakleekeeeikeleesleektlelevce.nelqrkkseaellrekvekleeelkelreelselsleeeea 113
                 +QL  ++ + t+k++e+  l+a+l    ++ e++ +++++  + l++k++ +++   ++ q+ ++e+  lre+++     +++lr + ++ ++++ ++
  EEA23037.1 151 EQLALAREDATKKAGEVAILRANLTKQAKEFERTIASLRTQLTDLTTKNKGVQQAAiDDRQKLETENLFLREELRDETLRVNNLRAKKRTEAPQTPRK 248
                 78999999**************999888888888777777777788888888776525667778999999**99999999999998777766555444 PP

>> CC2-LZ  Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   7.5   0.00025       0.5      13      99 ..     143     234 ..     133     235 .. 0.82

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00025
      CC2-LZ  13 keeieeLkaqlqaaeealaakqeeidelkeeikkkeeele.tisvlkaQa.evYrsD...FeaEReaReklheekerlaaqleelqkqneqL 99 
                  ++++ +++ql  a e  ++k  e+  l+++++k+ +e e ti  l++Q  ++  +     +a  ++R+kl +e+  l ++l++   ++++L
  EEA23037.1 143 SRQYDAINEQLALAREDATKKAGEVAILRANLTKQAKEFErTIASLRTQLtDLTTKNkgvQQAAIDDRQKLETENLFLREELRDETLRVNNL 234
                 689**********************************************6366666522234555679999999998888888888887777 PP

>> YfhD  YfhD-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.9   0.2    0.0017       3.3      31      54 ..     140     163 ..     126     165 .. 0.92
   2 ?    1.5   0.0      0.17   3.4e+02       9      25 ..     234     250 ..     229     260 .. 0.70

  Alignments for each domain:
  == domain 1  score: 7.9 bits;  conditional E-value: 0.0017
        YfhD  31 vEfSkelADheDleAnaRakaAda 54 
                 +EfS+  ++++++ A+aR +a+++
  EEA23037.1 140 EEFSRQYDAINEQLALAREDATKK 163
                 6********************985 PP

  == domain 2  score: 1.5 bits;  conditional E-value: 0.17
        YfhD   9 nrdknKatlpQvPkkek 25 
                  r k++ ++pQ+P k++
  EEA23037.1 234 LRAKKRTEAPQTPRKQR 250
                 567788889****9994 PP

>> TPR_MLP1_2  TPR/MLP1/MLP2-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   3.7   4.6e-05     0.092      56     120 ..     136     200 ..     112     204 .. 0.84
   2 ?   -1.7   0.1       1.4   2.8e+03      13      40 ..     206     233 ..     201     241 .. 0.63

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 4.6e-05
  TPR_MLP1_2  56 vkelqalreelnelkaeiaelkaeaesakaeleeseesweeqkeelekelselekriedlneqNk 120
                    ++++  +++ +++++a ++++a +   e++  ++++++q +e+e+ +++l+++++dl+++Nk
  EEA23037.1 136 GARIEEFSRQYDAINEQLALAREDATKKAGEVAILRANLTKQAKEFERTIASLRTQLTDLTTKNK 200
                 45799999********************************************************8 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 1.4
  TPR_MLP1_2  13 lkeekeeaeaklqklqedlekqaeiake 40 
                 + ++ +++e++   l+e+l+ ++ ++++
  EEA23037.1 206 AIDDRQKLETENLFLREELRDETLRVNN 233
                 5566666777777777777766655554 PP

>> V_ATPase_I  V-type ATPase 116kDa subunit family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   4.3   0.00018      0.36      19     119 ..     125     223 ..     119     262 .. 0.75

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00018
  V_ATPase_I  19 nafqrkfvkev.rrcdemerklrfleeeieklekavikeeeaeesleapeekeldeleeelekleeelkelnenleklkkelnelvelkavlekakefl 116
                 + +q+++ +e+  r++e +r+++ ++e+++ +++  +k+  +++ l+a+ +k+ +e e+++ +l ++l++l+++++ +++     ++ ++ le+ + fl
  EEA23037.1 125 QPVQHNHDHEIgARIEEFSRQYDAINEQLALAREDATKKAGEVAILRANLTKQAKEFERTIASLRTQLTDLTTKNKGVQQAA---IDDRQKLETENLFL 220
                 56777777777569*****************99999999999********************************99998754...45555555555555 PP

  V_ATPase_I 117 eee 119
                 +ee
  EEA23037.1 221 REE 223
                 544 PP

>> YabA  Initiation control protein YabA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       2.1   4.2e+03       5      37 ..     134     166 ..     131     175 .. 0.64
   2 ?   10.7   2.6   0.00032      0.63       4      53 ..     172     235 ..     169     259 .. 0.69

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 2.1
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
        YabA   5 elfdkleeleeqleelleeleelkeelaellee 37 
                 e+ +++ee+++q ++++e+l+  +e+ ++   e
  EEA23037.1 134 EIGARIEEFSRQYDAINEQLALAREDATKKAGE 166
                 666777777777777777777666666555544 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 0.00032
                 HHHHHHHHHHHHHHHHHHHHHHHHHHH....HHHHHHHHHHHHHHHHHHHHHH..........X CS
        YabA   4 kelfdkleeleeqleelleeleelkee....laelleenaeLeleneklrerl..........e 53 
                  +l+++ +e+e+++++l ++l++l ++     ++ +++ ++Le+en  lre+l          +
  EEA23037.1 172 ANLTKQAKEFERTIASLRTQLTDLTTKnkgvQQAAIDDRQKLETENLFLREELrdetlrvnnlR 235
                 579999999*********999999766122134578999**************77666543221 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (748 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       868  (0.0484132); expected 358.6 (0.02)
Passed bias filter:                      536  (0.0298957); expected 358.6 (0.02)
Passed Vit filter:                        65  (0.00362541); expected 17.9 (0.001)
Passed Fwd filter:                        11  (0.000613531); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               9  [number of targets reported over threshold]
# CPU time: 0.85u 0.34s 00:00:01.19 Elapsed: 00:00:00.55
# Mc/sec: 4107.03
//
Query:       EEA23038.1  [L=439]
Description: 30S ribosomal subunit S4, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      3e-14   52.4   0.0    6.5e-14   51.4   0.0    1.6  1  S4             S4 domain
  ------ inclusion threshold ------
      0.034   15.3   1.0      0.034   15.3   1.0    2.5  2  SPG4           Stationary phase protein 4
      0.076   12.8   0.0       0.16   11.8   0.0    1.5  1  S4_2           S4 domain
        3.7    5.9  10.1        5.1    5.5  10.1    1.1  1  Peptidase_S64  Peptidase family S64
        5.1    6.9  10.1       0.35   10.7   0.3    2.3  2  TraF           F plasmid transfer operon protein


Domain annotation for each model (and alignments):
>> S4  S4 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   51.4   0.0   1.8e-17   6.5e-14       1      46 [.     122     167 ..     122     169 .. 0.98

  Alignments for each domain:
  == domain 1  score: 51.4 bits;  conditional E-value: 1.8e-17
                 EEHHHHHHHTTSSSSHHHHHHHHHTTTEEETTEEE--TT-EE-TTC CS
          S4   1 rRLdkvlarlglassrreArqlIehGrVlVNGkvvkdpsyrVkpgD 46 
                 rRLd+ ++r+ +ass r+Arq++ hG V+VNGk+ + p+y + pgD
  EEA23038.1 122 RRLDVAIFRAMFASSTRQARQFVVHGAVTVNGKKMQFPGYLLNPGD 167
                 8********************************************9 PP

>> SPG4  Stationary phase protein 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   1.0     0.078   2.8e+02      62      88 ..     199     225 ..     175     273 .. 0.59
   2 ?   15.3   1.0   9.4e-06     0.034      43      99 ..     305     361 ..     292     368 .. 0.64

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.078
        SPG4  62 sessseslkeeegaakapnmvdiskls 88 
                 ++++ e++++ee++++++  +++sk  
  EEA23038.1 199 ASKTDEAENSEESTTETKAEEEVSKEV 225
                 222222222222222333333333322 PP

  == domain 2  score: 15.3 bits;  conditional E-value: 9.4e-06
        SPG4  43 epkkkkkkdeeelakaeetsessseslkeeegaakapnmvdisklsqnEfkrlyesl 99 
                  +kk+++++++ + ++++ts  s+e ++   +aa++pn vd s+l+++Ef+ l++++
  EEA23038.1 305 RNKKDAATKTDDVVAEDSTSGLSEELKEAFRQAAENPNSVDASELTEDEFEILKQAI 361
                 233333333333334444444444444444455667***************999875 PP

>> S4_2  S4 domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.8   0.0   4.4e-05      0.16      23      61 ..     137     175 ..     130     178 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 4.4e-05
        S4_2  23 GgeaKafiaegeVkvNGevetrRgkKlraGdvVeidget 61 
                   +a++f+  g+V+vNG++ +  g  l +Gd+ +++ e+
  EEA23038.1 137 TRQARQFVVHGAVTVNGKKMQFPGYLLNPGDLFQVEPER 175
                 569***************************999987766 PP

>> Peptidase_S64  Peptidase family S64
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.5  10.1    0.0014       5.1      12     186 ..     195     366 ..     183     389 .. 0.54

  Alignments for each domain:
  == domain 1  score: 5.5 bits;  conditional E-value: 0.0014
  Peptidase_S64  12 kdeeskekkslepsksnskskesgesss.slkelrpifesekaseeessaeedsstelaesssekssskqssSlfSksrktystkqssakssssk. 105
                    +++ ++++ ++e+s++++++++++e+ s ++++ ++++++  a++++ +++e++    +++++    +k  +S+ Sks  t+   + s +s+ s+ 
     EEA23038.1 195 AKRAASKTDEAENSEESTTETKAEEEVSkEVQDPKETLQRLLAQAKTIMSREKDVLPAKKKQELRGFQKVVRSVLSKSA-TSTILADSLESQFSEl 289
                    22333333333333333333333333332555555565555566666666666666666788889999999*****554.4444555666666653 PP

  Peptidase_S64 106 ..akksssvakaedvgkplrvleteklts.lntvleeeeeskekseesesssseekessvkeleeesvekeLkqLeedlaelmd 186
                            +ak+ + g + r  + +  t+  ++v+e++++  +++   +++ ++  e+ ++  ++e  e+e+++L++ +a++ d
     EEA23038.1 290 lgL----LKAKKAESGPSRRNKK-DAATKtDDVVAEDSTSGLSEE--LKEAFRQAAENPNSVDASELTEDEFEILKQAIAQMRD 366
                    331....2334444444444444.555551444444444444444..3344444444555556667777888888887777655 PP

>> TraF  F plasmid transfer operon protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.8   4.4      0.32   1.1e+03      15      57 ..     198     240 ..     182     273 .. 0.70
   2 ?   10.7   0.3   9.8e-05      0.35      14      64 ..     295     345 ..     284     361 .. 0.87

  Alignments for each domain:
  == domain 1  score: -0.8 bits;  conditional E-value: 0.32
        TraF  15 kkekakppkaakpalkeptseesatesaaelrkeleelldkAi 57 
                  + k+++ ++++ +++e++ ee   +++++ +++l++ll++A 
  EEA23038.1 198 AASKTDEAENSEESTTETKAEEEVSKEVQDPKETLQRLLAQAK 240
                 3333334444444555667777888899999999999999986 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 9.8e-05
        TraF  14 ekkekakppkaakpalkeptseesatesaaelrkeleelldkAilnPteen 64 
                  kk+++ p++ +k+ ++++t+ ++a+ s + l +el+e+ ++A  nP+  +
  EEA23038.1 295 AKKAESGPSRRNKKDAATKTDDVVAEDSTSGLSEELKEAFRQAAENPNSVD 345
                 5778888888888889999****************************9765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (439 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1723  (0.0961013); expected 358.6 (0.02)
Passed bias filter:                      672  (0.0374812); expected 358.6 (0.02)
Passed Vit filter:                        72  (0.00401584); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.67u 0.31s 00:00:00.98 Elapsed: 00:00:00.48
# Mc/sec: 2730.67
//
Query:       EEA23039.1  [L=549]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
  ------ inclusion threshold ------
       0.99    7.4   7.9          1    7.4   0.1    2.3  2  DNA_pol_phi  DNA polymerase phi
        4.5    6.8  16.6        1.1    8.7   9.2    2.4  2  PPP4R2       PPP4R2


Domain annotation for each model (and alignments):
>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   3.8    0.0052        47     640     691 ..     102     128 ..      18     157 .. 0.69
   2 ?    7.4   0.1   0.00012         1     295     353 ..     419     474 ..     417     484 .. 0.87

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.0052
  DNA_pol_phi 640 dededeeddeeeeeeddeededseedddeeesdedeededdedvdeid.elre 691
                  d+de++e+d + ee  d+e e                          d  +r+
   EEA23039.1 102 DDDEEDEEDGDAEERGDSEGE--------------------------DiHFRS 128
                  222222222222222222222..........................233333 PP

  == domain 2  score: 7.4 bits;  conditional E-value: 0.00012
  DNA_pol_phi 295 sedryLhkaaqkalkeiqevvkkdpekalavltaLlgkngslnfDkltktktvekllks 353
                  + d++L +a  ++l+++ +  +k + +  +++ aL    g++n+Dk t+   +e+ ++s
   EEA23039.1 419 AVDSNLTSAVLETLTKLNKHLEKADRTSSPIVAAL---TGNQNNDKDTNNTATENGVSS 474
                  56899******************************...589*******99999887743 PP

>> PPP4R2  PPP4R2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.7   9.2   0.00013       1.1     139     252 ..      28     138 ..       8     157 .. 0.64
   2 ?    2.0   0.7     0.014   1.2e+02     179     241 ..     427     483 ..     406     534 .. 0.64

  Alignments for each domain:
  == domain 1  score: 8.7 bits;  conditional E-value: 0.00013
      PPP4R2 139 eaeeeksnsesseniingvlseelnsekeedkansssqedsedvslvsipwvdekteselspfikeidsimsvnlgfedeeekeeddneseesasesee 237
                 +++++ +++++s    ng  +  l+s ++++ +     +d++ + ++s +  +  ++ +++++ + ++si+s++ +++d+ee+eed + +e  +se e+
  EEA23039.1  28 QQQAQPQQQQQSARQDNGYGRWRLPSVMQPSGQ---AANDKNSSNHTSSSAANGRATPPRDASMARPESIISASVSGDDDEEDEEDGDAEERGDSEGED 123
                 222222222233333333333333333444433...3446667777777788899999***************************88777888888888 PP

      PPP4R2 238 iteekdesvkveekd 252
                 i   ++ +  + +++
  EEA23039.1 124 IHFRSSRNEANPAAT 138
                 777776666655533 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.014
      PPP4R2 179 sedvslvsipwvdekteselspfikeidsimsvnlgfedeeekeeddneseesaseseeitee 241
                    ++l++++   ek+++ +sp  + ++     +++++d++++++   e+++s+s+s+ + + 
  EEA23039.1 427 AVLETLTKLNKHLEKADRTSSPIVAALTGN---QNNDKDTNNTAT---ENGVSSSSSTPDQAD 483
                 555677788888888888888888887744...333333333333...223333333322222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (549 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1721  (0.0959897); expected 358.6 (0.02)
Passed bias filter:                      592  (0.0330191); expected 358.6 (0.02)
Passed Vit filter:                        80  (0.00446204); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.78u 0.34s 00:00:01.12 Elapsed: 00:00:00.49
# Mc/sec: 3366.07
//
Query:       EEA23040.1  [L=407]
Description: pyruvate dehydrogenase E1 component alpha subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   4.4e-114  380.5   0.1   5.3e-114  380.2   0.1    1.1  1  E1_dh           Dehydrogenase E1 component
     0.0002   20.7   0.0    0.00037   19.8   0.0    1.4  1  DXP_synthase_N  1-deoxy-D-xylulose-5-phosphate synthase


Domain annotation for each model (and alignments):
>> E1_dh  Dehydrogenase E1 component
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  380.2   0.1  5.9e-118  5.3e-114       1     299 [.      82     377 ..      82     378 .. 0.98

  Alignments for each domain:
  == domain 1  score: 380.2 bits;  conditional E-value: 5.9e-118
                 HHHHHHHHHHHHHHHHHHTTSS-S-----TT-HHHHHHHHHTS-TTSEEEESS--HHHHHHTT--HHHHHHHHTT-T....TTSSGTT-.-E..BTT.. CS
       E1_dh   1 eklvllrrvedaldalykrkkrigfyhlsagqealkvgiaaalekeDliiteYReagvllarglsleeilaeltgkv....kgkggsrhelmyaekesr 95 
                 +++v++rr+e+a+d+lyk+kk++gf+hls+gqea++vgi++a++++D +it+YR++g+ l+rg ++++i+ el g++     gkggs+h +   + +  
  EEA23040.1  82 YDMVAIRRMEMAADRLYKEKKIRGFCHLSVGQEAVAVGIEHAITPQDKLITAYRCHGFALMRGGTVKSIIGELLGRRegiaYGKGGSMH-MF--APN-- 175
                 689**************************************************************************99999*******.66..677.. PP

                 BEEE-SSTTTHHHHHHHHHHHHHHHTS---EEEEEEGGGTT-HHHHHHHHHHHHTT--EEEEEEEESEETTEEHHHH-S---GGG..TTTTS-EEEEET CS
       E1_dh  96 ilggngivgaqvplvaGialaakiegkkevailliGDgAanqGdvyealnlaalwklpvifvveNNkygisTeaekasaskeladrargvgipglrVdg 194
                 ++ggngivgaqvp++aG+a+a++++g+k+++i+l+GDgA+nqG+v+ea+n+a+lw+lpv+f +eNNkyg++T+a+++sa +++++  rg++ipg++V+g
  EEA23040.1 176 FYGGNGIVGAQVPVGAGLAFAQQYNGEKTCSIALYGDGASNQGQVFEAYNMAKLWNLPVLFGCENNKYGMGTSAARSSALTDYYK--RGQYIPGIKVNG 272
                 *************************************************************************************..************ PP

                 TSHHHHHHHHHHHHHHHHTTT--EEEEEEE--SS-SSTTSHSHSSSHHHHHHHHHHHH-HHHHHHHHHHHTTSS-HHHHHHHHHHHHHHHHHHHHHHHH CS
       E1_dh 195 nDplavyeAvkfAaeraregkgpllielvtYRyggHsesDdpstyrtreeveevrkkkdpiqrlkelLvkkgvvseeelkeiekevrkeveeavkkaes 293
                 +D+la+++Av+  +e+a +gkgpl+ e+vtYRyggHs+sD+++tyr+ree++ +r+++d i++lk++L +++vv+eeelk+i+ke+r+ ++e+v+ ae+
  EEA23040.1 273 MDVLAIKAAVQYGREYATSGKGPLVYEYVTYRYGGHSMSDPGTTYRSREEIQRMRSTHDAIAGLKQKLLDWSVVTEEELKAIDKEARAFIDEEVAVAEQ 371
                 **************************************************************************************************9 PP

                 S----G CS
       E1_dh 294 kkelep 299
                    +ep
  EEA23040.1 372 MAPPEP 377
                 887765 PP

>> DXP_synthase_N  1-deoxy-D-xylulose-5-phosphate synthase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.8   0.0   4.1e-08   0.00037     115     173 ..     185     243 ..     178     305 .. 0.83

  Alignments for each domain:
  == domain 1  score: 19.8 bits;  conditional E-value: 4.1e-08
  DXP_synthase_N 115 tsisaalGlavardlkgekkkvvaviGDgaltgGmafealnnigelkkkllvilNdNem 173
                     + + ++ Gla a++++gek+  +a+ GDga   G  fea n ++  +  +l    +N+ 
      EEA23040.1 185 AQVPVGAGLAFAQQYNGEKTCSIALYGDGASNQGQVFEAYNMAKLWNLPVLFGCENNKY 243
                     5667899**********************************999888777776666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (407 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       563  (0.0314016); expected 358.6 (0.02)
Passed bias filter:                      495  (0.0276089); expected 358.6 (0.02)
Passed Vit filter:                        41  (0.0022868); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.59u 0.27s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 2589.28
//
Query:       EEA23041.1  [L=1016]
Description: von Willebrand and RING finger domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.1e-26   93.5   0.1    2.9e-26   92.1   0.1    1.8  1  PH_10           Pleckstrin homology domain
    1.9e-12   47.7   0.0    3.9e-12   46.8   0.0    1.5  1  VWA             von Willebrand factor type A domain
    3.5e-09   36.8   0.1    2.4e-07   30.8   0.0    3.0  2  VWA_3           von Willebrand factor type A domain
    0.00089   19.5   5.4     0.0019   18.5   5.4    1.6  1  zf-RING_2       Ring finger domain
     0.0033   17.4   6.0     0.0064   16.4   6.0    1.5  1  zf-RING_5       zinc-RING finger domain
     0.0043   17.3   2.9      0.012   15.9   2.9    1.7  1  zf-rbx1         RING-H2 zinc finger domain
  ------ inclusion threshold ------
      0.011   15.3   3.0      0.011   15.3   3.0    2.2  2  Zn_ribbon_17    Zinc-ribbon, C4HC2 type
      0.013   15.4   6.2      0.028   14.3   6.2    1.6  1  zf-C3HC4        Zinc finger, C3HC4 type (RING finger)
      0.014   15.2   4.9      0.039   13.8   4.9    1.8  1  zf-C3HC4_2      Zinc finger, C3HC4 type (RING finger)
      0.048   14.0   4.8        0.1   13.0   4.8    1.6  1  zf-RING-like    RING-like domain
      0.074   12.9   2.2       0.18   11.7   2.2    1.6  1  zf-C3HC4_3      Zinc finger, C3HC4 type (RING finger)
       0.27   11.4   0.7       0.52   10.5   0.7    1.4  1  zf-UDP          Zinc-binding RING-finger
       0.59   10.2   5.5        1.5    9.0   5.5    1.7  1  zf-C3H2C3       Zinc-finger
        1.4    8.8   3.4        3.3    7.5   3.4    1.7  1  zf-RING_11      RING-like zinc finger
        1.5    8.9   3.8          4    7.6   0.1    2.8  2  Rod_cone_degen  Progressive rod-cone degeneration


Domain annotation for each model (and alignments):
>> PH_10  Pleckstrin homology domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   92.1   0.1   2.4e-29   2.9e-26       1     122 [.     316     424 ..     316     425 .. 0.82

  Alignments for each domain:
  == domain 1  score: 92.1 bits;  conditional E-value: 2.4e-29
       PH_10   1 ekfGeLllhdtltVkkdsdsereyevyLFekillcvkevkeekkkksksssllkkkssssskkkktklqLKGrilis.nvtevtssskpgsyslqiswk 98 
                 ++fG+Lllh+ l+V+kd++s++e+e+yLF+++l+cvke    kk  s+           +sk+k+ +++LKG+ili+ +++ev+ ++  ++ +l++++ 
  EEA23041.1 316 QRFGKLLLHGSLNVGKDRESWQELECYLFAEMLICVKE----KKMASDAAAY-------ESKRKSGRCSLKGSILIKkHLREVVVVT--EEPILTLNLI 401
                 58************************************....2333322332.......23499********************755..5555555555 PP

       PH_10  99 gdkelesftlrfkneeqlkkWesa 122
                    +l++f+lrf+n+ ql+ W++a
  EEA23041.1 402 -VSDLPCFHLRFQNRGQLDLWRRA 424
                 .226*****************986 PP

>> VWA  von Willebrand factor type A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.8   0.0   3.3e-15   3.9e-12       1     170 [.     496     662 ..     496     666 .. 0.90

  Alignments for each domain:
  == domain 1  score: 46.8 bits;  conditional E-value: 3.3e-15
                 EEEEEEE-STTSCHHHHHHHHHHHHHHHHHHTBTTTTEEEEEEEESSS..EEEEEETTSHC..HHHHHHHHHHTGSGGGGSSC-HHHHHHHHHHHHHHH CS
         VWA   1 DivfvlDgSgsmgeenfekvkefikklveklevgpegtrvglvqfsse..vktefslndys..skeellsalnnlkysgggttntgkalkyaleklfks 95 
                 D+v+v+ +S+sm++ +++  ++++  lv +l    +++r+glv+f+s+    + + ++++      ++l++l+ + +++   + + ++ + a++ l+++
  EEA23041.1 496 DLVVVIPVSSSMQGLKITLLRDALRFLVLNLG---PRDRMGLVTFGSSggGVPLVGMTTKAwnGWGKILNSLRPVGQKSLRAD-VVEGANVAMDLLMQR 590
                 9*******************************...*************99445555555444377*********877766666.*************** PP

                 HGTSSTTSEEEEEEEESS--CS.SHTHHHHHHHHGCTEEEEEEEESSSHHHHHHHHHSSSSCHHCEEEESSHHHHH CS
         VWA  96 sagaRenakkviilltdGksnd.gdpkeaaneakeqgikvfavGvgnadekelLnkiasepgeghvftvtdfeele 170
                 +++   n  + i+l++d  ++d ++++ ++ +a ++++ ++++G g  ++ + L ++++ ++  ++ +v+d+  l+
  EEA23041.1 591 KSN---NPISTILLISDSSTSDpESVDFVVSRAEAAKVGIHSFGLGLTHKPDTLIELSTRTK-ACYTYVKDWMMLR 662
                 ***...999********9999966*********************************99999.9999999998665 PP

>> VWA_3  von Willebrand factor type A domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.8   0.0     2e-10   2.4e-07       2     150 ..     496     649 ..     495     653 .. 0.73
   2 ?    1.6   0.0       0.2   2.3e+02      51      88 ..     934     969 ..     925     985 .. 0.68

  Alignments for each domain:
  == domain 1  score: 30.8 bits;  conditional E-value: 2e-10
       VWA_3   2 evvivvDvsssmsaen.klvkdaLsvalrqLptndkiavllfgt.........kprplfpgsravsaaelqealqkikelelslgasnlegaLkealrq 90 
                 ++v+v+ vsssm++ + +l++daL++++  L ++d++ ++ fg+          + + + g+ ++   +l+ + qk    ++ +ga     a++    q
  EEA23041.1 496 DLVVVIPVSSSMQGLKiTLLRDALRFLVLNLGPRDRMGLVTFGSsgggvplvgMTTKAWNGWGKIL-NSLRPVGQKSLRADVVEGAN---VAMDLL-MQ 589
                 79******************************************5544444443344555555555.55555555444434423222...222223.35 PP

       VWA_3  91 pakpgevrsvilltDgssaqgeervsdlisrar.ekirfhalglgsslsaamlqaLAeasg 150
                 ++++  +++++l++D+s  +  e+v   +sra  +k+ +h++glg +++++ l +L+ +++
  EEA23041.1 590 RKSNNPISTILLISDSST-SDPESVDFVVSRAEaAKVGIHSFGLGLTHKPDTLIELSTRTK 649
                 678999**********95.44445666677655599*******************999876 PP

  == domain 2  score: 1.6 bits;  conditional E-value: 0.2
       VWA_3  51 pgsravsaaelqealqkike..lelslgasnlegaLkeal 88 
                 ++ +++ +a+l++al++i++       ++ + ++a  +a+
  EEA23041.1 934 QHVMSALDADLEAALEWINHpaV----FGRDSRKAVLQAI 969
                 7889999*************333....4444444444333 PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   5.4   1.6e-06    0.0019       2      44 .]      18      65 ..      17      65 .. 0.77

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 1.6e-06
   zf-RING_2  2 eCpICleel...ssadsvlllpCgHvfhreClerwlrssst..CPlCr 44
                 C++C e+l    +++++l+  C Hv h+ C+ +++++ ++  CP+C+
  EEA23041.1 18 ACAVCEEPLehtLRGERILQFSCTHVSHEACFYEYIKEFESqyCPTCN 65
                6****99994333444455557************988777779****5 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   6.0   5.4e-06    0.0064       2      43 ..      19      65 ..      18      66 .. 0.88

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 5.4e-06
   zf-RING_5  2 CnkCfekl...skeekfyltsCgHifCekClkkll..ekeavCpiCr 43
                C +C e+l      e++   sC+H+ +e+C+ ++    ++++Cp+C+
  EEA23041.1 19 CAVCEEPLehtLRGERILQFSCTHVSHEACFYEYIkeFESQYCPTCN 65
                9*******65545555*******************999********7 PP

>> zf-rbx1  RING-H2 zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   2.9   9.7e-06     0.012      12      55 .]      17      65 ..      12      65 .. 0.82

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 9.7e-06
     zf-rbx1 12 eacieckapgdee...cpvvlGeCgHaFHlhCiskWlkt..rkvCPlcr 55
                +ac  c++p +++     + + +C+H+ H  C  +++k+  ++ CP+c+
  EEA23041.1 17 SACAVCEEPLEHTlrgERILQFSCTHVSHEACFYEYIKEfeSQYCPTCN 65
                56777777777777765666779****************99999****8 PP

>> Zn_ribbon_17  Zinc-ribbon, C4HC2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   15.3   3.0   9.2e-06     0.011       6      47 ..      18      63 ..      14      67 .. 0.82
   2 ?   -0.5   0.2      0.81   9.7e+02      42      49 ..     661     668 ..     649     676 .. 0.69

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 9.2e-06
  Zn_ribbon_17  6 sCayCe....lavkgrvvlcgvCeHvlHasCarewfenddlaeCps 47
                   Ca+Ce     +++g  +l  +C Hv H++C  e  ++ +++ Cp+
    EEA23041.1 18 ACAVCEepleHTLRGERILQFSCTHVSHEACFYEYIKEFESQYCPT 63
                  699997222246789999****************999988899996 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.81
  Zn_ribbon_17  42 laeCpsGC 49 
                   l eC++GC
    EEA23041.1 661 LRECVAGC 668
                   459***** PP

>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.3   6.2   2.4e-05     0.028       1      41 []      19      64 ..      19      64 .. 0.96

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2.4e-05
                -TTT-S--SS-E......E-TTS--B-CHHHHHHHHCTSSB--TTT CS
    zf-C3HC4  1 CpiCleeakepn.....elleCkHsfCskCirkilksrkkvkCPlC 41
                C++C e ++ +          C+H  +++C  +++k+ ++++CP+C
  EEA23041.1 19 CAVCEEPLEHTLrgeriLQFSCTHVSHEACFYEYIKEFESQYCPTC 64
                **********99***99999****************988899**** PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   4.9   3.2e-05     0.039       2      40 .]      19      64 ..      18      64 .. 0.82

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 3.2e-05
  zf-C3HC4_2  2 CpiCldmlkdpsvvt.....pCgHvfCqkCilrsLeekn..eCPlC 40
                C++C + l+ +++        C Hv ++ C+ ++++e +   CP+C
  EEA23041.1 19 CAVCEEPLEHTLRGErilqfSCTHVSHEACFYEYIKEFEsqYCPTC 64
                *********987644455569************999754459**** PP

>> zf-RING-like  RING-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   4.8   8.4e-05       0.1       1      43 []      19      64 ..      19      64 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 8.4e-05
  zf-RING-like  1 CeaCke...ivtqGvrCsnesCnvrlHvdCfqhyirthsskkCpkC 43
                  C++C+e     ++G r  + sC+   H+ Cf +yi++ +s+ Cp+C
    EEA23041.1 19 CAVCEEpleHTLRGERILQFSCTHVSHEACFYEYIKEFESQYCPTC 64
                  666664111345666667789************************* PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   2.2   0.00015      0.18       4      46 ..      18      67 ..      15      69 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00015
                B-TTTSS......SBS-EEETTEEEEEE-HHHHHHHHH..TT-B-TTT--B CS
  zf-C3HC4_3  4 eCviCle......rprnvvllpCgHlvlCeeCaekllk..rkkkCpiCrrp 46
                 C +C e      r + ++   C H+   e+C+ ++ k  +++ Cp C++p
  EEA23041.1 18 ACAVCEEplehtlRGERILQFSCTHV-SHEACFYEYIKefESQYCPTCNAP 67
                6999999776665566677778****.99*******999*********998 PP

>> zf-UDP  Zinc-binding RING-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.7   0.00043      0.52       6      58 ..      14      66 ..       9      74 .. 0.79

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00043
      zf-UDP  6 lngqiCqiCgddvgltedgelFv..acnecafpvcrpcyeyerkdgnqsCPqCkt 58
                + g  C +C + ++ t  ge      c++++   c   yey +   +q CP C++
  EEA23041.1 14 FVGSACAVCEEPLEHTLRGERILqfSCTHVSHEAC--FYEYIKEFESQYCPTCNA 66
                56789**************9764114555555555..59**999999******97 PP

>> zf-C3H2C3  Zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   5.5    0.0012       1.5       1      35 []      19      65 ..      19      65 .. 0.66

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.0012
   zf-C3H2C3  1 CdnCglkLdyp.....fvaysCkHlvHakCade.......evCPkCk 35
                C  C+ +L+       + ++sC H+ H  C  e       + CP+C+
  EEA23041.1 19 CAVCEEPLEHTlrgerILQFSCTHVSHEACFYEyikefesQYCPTCN 65
                7788888887622222579***********654122222256**997 PP

>> zf-RING_11  RING-like zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.5   3.4    0.0027       3.3       2      28 ..      19      48 ..      18      49 .. 0.92

  Alignments for each domain:
  == domain 1  score: 7.5 bits;  conditional E-value: 0.0027
  zf-RING_11  2 CsICLeefk...pgqalfilpCsHtFHfkC 28
                C++C e+++   +g+++   +C H+ H  C
  EEA23041.1 19 CAVCEEPLEhtlRGERILQFSCTHVSHEAC 48
                ****99999777899**999********** PP

>> Rod_cone_degen  Progressive rod-cone degeneration
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   1.0      0.54   6.5e+02      33      50 ..     177     194 ..     160     196 .. 0.72
   2 ?    7.6   0.1    0.0034         4      14      29 ..     420     435 ..     418     457 .. 0.76

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.54
  Rod_cone_degen  33 avvGsssdaDlqssGRek 50 
                     a  G   d   qs+GR++
      EEA23041.1 177 ASSGEYTDGQQQSTGRRH 194
                     45677788899*****86 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0034
  Rod_cone_degen  14 LWRRRfanRvqPePsd 29 
                     LWRR fa   +PeP +
      EEA23041.1 420 LWRRAFAGLHNPEPVR 435
                     9*************75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1016 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1231  (0.0686597); expected 358.6 (0.02)
Passed bias filter:                      597  (0.033298); expected 358.6 (0.02)
Passed Vit filter:                        67  (0.00373696); expected 17.9 (0.001)
Passed Fwd filter:                        17  (0.000948185); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.88u 0.27s 00:00:01.14 Elapsed: 00:00:00.48
# Mc/sec: 6347.04
//
Query:       EEA23042.1  [L=581]
Description: t-complex protein 1, theta subunit, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
     4e-148  494.1   7.1   4.6e-148  493.9   7.1    1.0  1  Cpn60_TCP1       TCP-1/cpn60 chaperonin family
      0.009   15.6   0.1      0.025   14.1   0.0    1.7  2  EAL              EAL domain
  ------ inclusion threshold ------
      0.027   14.1   0.3      0.087   12.4   0.1    2.0  2  PrpR_N           Propionate catabolism activator
      0.036   13.8   1.2       0.11   12.3   1.2    1.8  1  TFB6             Subunit 11 of the general transcription fact
      0.063   14.2   9.8       0.18   12.7   9.8    1.8  1  WRNPLPNID        Putative WW-binding domain and destruction b
      0.098   12.7   4.0       0.23   11.4   4.0    1.6  1  RXT2_N           RXT2-like, N-terminal
       0.16   11.9   2.4       0.37   10.7   2.4    1.5  1  RPN2_C           26S proteasome regulatory subunit RPN2 C-ter
       0.26   11.5   8.9       0.49   10.6   8.9    1.4  1  RNA_pol_3_Rpc31  DNA-directed RNA polymerase III subunit Rpc3
       0.36   10.7   6.6      0.096   12.6   3.1    1.7  2  Sigma70_ner      Sigma-70, non-essential region
       0.84    9.0   8.7        1.5    8.2   8.7    1.3  1  SDA1             SDA1
        1.2    8.8   3.5        2.1    8.0   3.5    1.3  1  Pns11_12         Non-structural protein 11 and 12
          2    7.7   9.5          4    6.8   9.5    1.4  1  CobT             Cobalamin biosynthesis protein CobT
          3    7.5   6.0        6.2    6.5   6.0    1.5  1  FAM176           FAM176 family
        3.1    5.8  13.0        5.4    5.0  13.0    1.3  1  DNA_pol_phi      DNA polymerase phi
        3.3    7.0   8.9        5.1    6.3   8.9    1.2  1  NOA36            NOA36 protein
        3.7    8.0  12.8        8.7    6.8  12.8    1.6  1  CENP-B_dimeris   Centromere protein B dimerisation domain
        5.2    5.2  10.8          1    7.5   7.0    1.6  2  Nop14            Nop14-like family


Domain annotation for each model (and alignments):
>> Cpn60_TCP1  TCP-1/cpn60 chaperonin family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  493.9   7.1  4.4e-151  4.6e-148       1     490 [.      38     564 ..      38     565 .. 0.95

  Alignments for each domain:
  == domain 1  score: 493.9 bits;  conditional E-value: 4.4e-151
                 HHHHHHCCSSTTXXEEEEEETTSEEEEEXSHHHHHHCSXXXSHHHHHHHHHHHHCCCCCTTCHHHHHHHHHHHHHHHHHHHHCTXXHHHHHHHHHHHHH CS
  Cpn60_TCP1   1 ladivkttlGPkGmdKmlvnkggkvvvTnDGatilkeleiehPaakllveaaesqdeevGDGTttvviLageLleeaekliaagvhpttiiegyekale 99 
                 ++++v+++lGP G++K+++n+ +k+++T+D+atil+el++ hPaakllv+a+++qd e+GD T+ v+++ageLl++ae+l+++g+++++i++gyeka  
  EEA23042.1  38 ISQTVQSSLGPYGRNKIVINHLQKMFLTSDAATILRELDVVHPAAKLLVMASQQQDAEMGDATNLVIVFAGELLKKAEELLRMGLKTSDIVNGYEKAQG 136
                 789************************************************************************************************ PP

                 HHHHHHHHHXEEBXSCSTT.HHHHHHHHHHCTTSSXXSTHHHHHHHHHHHH.HCHCCCSEECSCCCEECCCCEECECTTSEEESEEEESS--SSTTSSC CS
  Cpn60_TCP1 100 kaleaLkeiaveisseekdreeLlkvartslsskltskeaeelsklvvdAv.klieenekeldlgrikvvkieggsledselveGlvldkgvlspdmpk 197
                  al+ L+  +v+  +e ++ +eL k+  t++ sk++ +e e l++lv +Av  ++++n +++++++++vvki ggsle+s++++G+v+ +++ ++   k
  EEA23042.1 137 FALKTLEDLEVDRLKEMRSATELSKALITVIASKQSGNE-EVLAALVSEAVlAVLPKNPTNFNVDNVRVVKIMGGSLEQSRVIKGMVFGREPDGQ--IK 232
                 *********9999999999***************88888.***********99999999***********************************9..9* PP

                 EEECEEEEEESS-BS--HHCCHHHCCCCSCCHHHHHHHHHHHHHHHHHHHHHHTTECEEEESS-B-HHHHHHHHHCT-EEE-S--HHHHHHHHHHHT-- CS
  Cpn60_TCP1 198 klenakvllldvsLeiektetkttvvlsdaeeleklekaeekqleellekiiksgvnvvvcqkgiddlalhflakngilalrrvkkkdlerlakatGat 296
                 k ++akv +++++++i +tetk+tv l++a+e+ +++k ee+ le  ++++ +sgv+vvv+   + +lalh+l++ +il+++ ++k++l+rl++++Gat
  EEA23042.1 233 KARKAKVGVFSCPIDISQTETKGTVLLKNAQEMLDFTKGEEDRLEAAIKELYDSGVRVVVAGSTVGELALHYLNRFNILVIKIMSKFELRRLCRVVGAT 331
                 *************************************************************************************************** PP

                 EBSCGGGGGCGC-EEEEEEEECCETTCCEEEEE...CESSSSXEEEEEEESTCCCHHHHHHHHHHHHHHHHHHHHHHEEEETTTCHHHHHHHHHHCCCC CS
  Cpn60_TCP1 297 avssledltpeelGtakkveeekigsekttiie...evksgkiatillrgatdtvldeieraiedAlnvvknaiedekvvpGGGatelelakklkeyak 392
                 ++++l+ + p+e+G+++ ve+++ig +++t+++     +  ++ati+lrgat++ ld++erai+d++n+vk++++d+++vpG+Gatel+la++++++a+
  EEA23042.1 332 PLARLGAPMPDEMGNIDVVETTEIGGDRVTVFRqedANTVTRTATIVLRGATQNHLDDVERAIDDGVNAVKAITKDPRLVPGAGATELQLAERISAFAD 430
                 *********************************5553377899******************************************************** PP

                 TSXCCHHHHHHHHHHHHTHHHHHHHHHCTSXHHHHHHHHHHHH...........................HTTX........TTEEEETTTTC...EEE CS
  Cpn60_TCP1 393 svsgeeqlaieafakALevipktLaeNaGldpievlaklraah...........................nkge........kelgidvesge...iid 453
                 +++g  q+ai+++a+A+ev+p++Lae aGld++evl++l+ ah                           +            ++g+d+  ++   +id
  EEA23042.1 431 KTPGLAQYAIKKYAEAFEVVPRSLAESAGLDATEVLSRLYTAHqrnkksdseeeedeeedsensgeeseeE--SdeddedpyWTTGVDLFGNSttgTID 527
                 *******************************************9999999888888888888666655551..0445556666788888766678899* PP

                 CCCCTXEEEHHHHHHHHHHHHHHHHHHHCEEEEEXXX CS
  Cpn60_TCP1 454 lveagvvDplkvkrqalksAteaastiLrideiikak 490
                 ++e+g++D ++ k++a+ +Ate+a+t+L++d+ii+a+
  EEA23042.1 528 ALEEGILDLMASKSWAIRLATESARTVLSVDQIIVAR 564
                 **********************************997 PP

>> EAL  EAL domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.5   0.0       5.5   5.8e+03     162     181 ..     138     157 ..     134     165 .. 0.80
   2 !   14.1   0.0   2.3e-05     0.025     134     180 ..     272     319 ..     260     323 .. 0.87

  Alignments for each domain:
  == domain 1  score: -3.5 bits;  conditional E-value: 5.5
                 CCHHHCCC--SEEEE-HHHH CS
         EAL 162 slsylarlppdiiKldrsll 181
                 +l+ l +l++d++K  rs++
  EEA23042.1 138 ALKTLEDLEVDRLKEMRSAT 157
                 67889999999999988887 PP

  == domain 2  score: 14.1 bits;  conditional E-value: 2.3e-05
                 HHHH..HHHHHHHCTT-EEEEEEETSSTCCCHHHCCC--SEEEE-HHH CS
         EAL 134 ealq.eevlarLralGirialddfgtgysslsylarlppdiiKldrsl 180
                 e+ + e+++++L + G+r+++++ + g+ +l+yl r+++ +iK+ + +
  EEA23042.1 272 EEDRlEAAIKELYDSGVRVVVAGSTVGELALHYLNRFNILVIKIMSKF 319
                 34444599************************************8765 PP

>> PrpR_N  Propionate catabolism activator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1   8.3e-05     0.087      69     135 ..     233     303 ..     229     317 .. 0.80
   2 ?   -3.2   0.0         5   5.3e+03       6      28 ..     386     407 ..     382     425 .. 0.66

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 8.3e-05
      PrpR_N  69 klg.ekialvgfeniikglktlsel.ldldieiytinseee..aeaavkelkaegvevvvGdgvvadlAek 135
                 k +  k+++++ +  i++++t   + l+   e+  +++ ee  +eaa+kel ++gv+vvv + +v +lA +
  EEA23042.1 233 KARkAKVGVFSCPIDISQTETKGTVlLKNAQEMLDFTKGEEdrLEAAIKELYDSGVRVVVAGSTVGELALH 303
                 4443688999999877777776666258888888888877777**********************999965 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 5
      PrpR_N   6 dievvegdleeavelakeleaeg 28 
                 +++ ve  ++++v+++k++ +++
  EEA23042.1 386 HLDDVERAIDDGVNAVKAI-TKD 407
                 5566777788888877776.444 PP

>> TFB6  Subunit 11 of the general transcription factor TFIIH
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   1.2    0.0001      0.11      80     153 ..     433     506 ..     426     516 .. 0.57

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 0.0001
        TFB6  80 pGfeeglragmstTdkVRlksivertRvlvvevlereeeeeeeeedeeededeeeeeeeeeeeeeeedeedede 153
                 pG  +   ++      V  +s++e++ +   evl+r  ++++++++++++e+e+eee++e++ ee+e+e+ded+
  EEA23042.1 433 PGLAQYAIKKYAEAFEVVPRSLAESAGLDATEVLSRLYTAHQRNKKSDSEEEEDEEEDSENSGEESEEESDEDD 506
                 55555555556666667779999999999999999987777744333333333333333333222222222222 PP

>> WRNPLPNID  Putative WW-binding domain and destruction box
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.7   9.8   0.00017      0.18      25      68 ..     471     513 ..     460     515 .. 0.54

  Alignments for each domain:
  == domain 1  score: 12.7 bits;  conditional E-value: 0.00017
   WRNPLPNID  25 lldseaeessegesvdedeeaeeeeeeeeeeedeedsgfngWit 68 
                 + +++ +++s+ e ++++ee++e++ ee eee++ed+++++W t
  EEA23042.1 471 TAHQR-NKKSDSEEEEDEEEDSENSGEESEEESDEDDEDPYWTT 513
                 44443.222222222333344444555555556777788***98 PP

>> RXT2_N  RXT2-like, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   4.0   0.00022      0.23      53      93 ..     471     511 ..     443     517 .. 0.64

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 0.00022
      RXT2_N  53 kkkekekeekeeeeedeegdeededdddeeeaeaaeenpyk 93 
                   ++++k++++eeeedee+d+e++ +++eee+++++e+py 
  EEA23042.1 471 TAHQRNKKSDSEEEEDEEEDSENSGEESEEESDEDDEDPYW 511
                 23445555555555555555555566666677788899985 PP

>> RPN2_C  26S proteasome regulatory subunit RPN2 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.7   2.4   0.00035      0.37      44      89 ..     462     506 ..     448     513 .. 0.64

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.00035
                 HHHHHHHHHHHHHHHHHHHHHG.----------------------- CS
      RPN2_C  44 atAvLSttakakarakkkekekeeeekeedkmdvdeekeekekkek 89 
                 at vLS    a +r+kk+++e+e e++eed+ +  ee+ee++++++
  EEA23042.1 462 ATEVLSRLYTAHQRNKKSDSEEE-EDEEEDSENSGEESEEESDEDD 506
                 68899999999999999999983.3333333333332222222222 PP

>> RNA_pol_3_Rpc31  DNA-directed RNA polymerase III subunit Rpc31
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   8.9   0.00046      0.49     165     211 ..     460     508 ..     418     510 .. 0.60

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00046
  RNA_pol_3_Rpc31 165 eegkelleklk..elaeeeddeeekkekedeeeee...eeeeddefdddded 211
                       ++ e+l++l    ++++++d    +e+edeee++    ee ++e+d+dded
       EEA23042.1 460 LDATEVLSRLYtaHQRNKKSDS---EEEEDEEEDSensGEESEEESDEDDED 508
                      4455556666555344455553...233333333333335555555555543 PP

>> Sigma70_ner  Sigma-70, non-essential region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.1       3.8     4e+03       7      32 ..     109     143 ..     108     180 .. 0.64
   2 ?   12.6   3.1   9.1e-05     0.096      19      65 ..     418     506 ..     414     538 .. 0.71

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 3.8
  Sigma70_ner   7 ellelydrveageirLrdiidGflD.........e 32 
                  ell+ ++++ +  ++ +di+ G+           e
   EEA23042.1 109 ELLKKAEELLRMGLKTSDIVNGYEKaqgfalktlE 143
                  57777777777778888888887665555554431 PP

  == domain 2  score: 12.6 bits;  conditional E-value: 9.1e-05
  Sigma70_ner  19 eirLrdiidGflD...................................................eeeeeeeeeeeedeeeeeeeedddeeeseseaad 65 
                  e++L++ i++f D                                                   e        eeedeee++e+  ++ +e+es+++d
   EEA23042.1 418 ELQLAERISAFADktpglaqyaikkyaeafevvprslaesagldatevlsrlytahqrnkksdsE--------EEEDEEEDSENSGEE-SEEESDEDD 506
                  88999999999999999999999999999999999999999999999999998876544332221........211211222211111.111222222 PP

>> SDA1  SDA1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.2   8.7    0.0014       1.5      75     120 ..     469     511 ..     442     516 .. 0.53

  Alignments for each domain:
  == domain 1  score: 8.2 bits;  conditional E-value: 0.0014
        SDA1  75 Llekwkeeekkekreeeeedsddeddeedwevesdddseedseggw 120
                 L+  +++++k++++  eeed++++++++++e e+++d+ +d++  w
  EEA23042.1 469 LYTAHQRNKKSDSE--EEEDEEEDSENSGEESEEESDE-DDEDPYW 511
                 55555555555555..3333222233333333333333.5554445 PP

>> Pns11_12  Non-structural protein 11 and 12
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   3.5     0.002       2.1     142     182 ..     469     510 ..     451     518 .. 0.76

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.002
    Pns11_12 142 GkgsfkknGkdrr.eedkrdeysednsykseeelsededapl 182
                    + ++n k  + ee+ ++e se+   +seee+ ed++ p 
  EEA23042.1 469 LYTAHQRNKKSDSeEEEDEEEDSENSGEESEEESDEDDEDPY 510
                 55666788775550556677888888899*******998875 PP

>> CobT  Cobalamin biosynthesis protein CobT
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   9.5    0.0038         4     195     239 ..     463     507 ..     458     513 .. 0.51

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0038
        CobT 195 rqlLqdldlaeesaeepeeedeeeeedeeeeeeeseeeeeegedd 239
                 +++L+ l  a+++++++++e+ee+ee+++e+  e++eee++++d+
  EEA23042.1 463 TEVLSRLYTAHQRNKKSDSEEEEDEEEDSENSGEESEEESDEDDE 507
                 567777776655555555444444444444444433333333333 PP

>> FAM176  FAM176 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.5   6.0    0.0059       6.2      60      89 ..     475     504 ..     461     531 .. 0.46

  Alignments for each domain:
  == domain 1  score: 6.5 bits;  conditional E-value: 0.0059
      FAM176  60 klkeesekasededeeeeeeeedsseseae 89 
                 ++k+++++++ede+e++e++ e+s+e++ e
  EEA23042.1 475 RNKKSDSEEEEDEEEDSENSGEESEEESDE 504
                 111111122222222222222222222211 PP

>> DNA_pol_phi  DNA polymerase phi
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.0  13.0    0.0051       5.4     642     676 ..     474     508 ..     460     518 .. 0.53

  Alignments for each domain:
  == domain 1  score: 5.0 bits;  conditional E-value: 0.0051
  DNA_pol_phi 642 dedeeddeeeeeeddeededseedddeeesdedee 676
                  + +++ d+eeee+++e++e+s e+++ee++++de+
   EEA23042.1 474 QRNKKSDSEEEEDEEEDSENSGEESEEESDEDDED 508
                  33344444444444444444444443333333333 PP

>> NOA36  NOA36 protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.3   8.9    0.0049       5.1     268     299 ..     474     506 ..     444     512 .. 0.45

  Alignments for each domain:
  == domain 1  score: 6.3 bits;  conditional E-value: 0.0049
       NOA36 268 deddegdedddddddeeddde.eeddedeeeee 299
                 ++++++d+++++d++e+++++ ee +e+++e++
  EEA23042.1 474 QRNKKSDSEEEEDEEEDSENSgEESEEESDEDD 506
                 222222222222222222221011111111111 PP

>> CENP-B_dimeris  Centromere protein B dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8  12.8    0.0082       8.7       9      39 ..     478     508 ..     470     523 .. 0.60

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0082
  CENP-B_dimeris   9 gedsesesdeeeeeeeedeededeeddeddd 39 
                       dse e deee+ e+  ee e+e d++d+d
      EEA23042.1 478 KSDSEEEEDEEEDSENSGEESEEESDEDDED 508
                     4566666677666666655555554444444 PP

>> Nop14  Nop14-like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.1      0.74   7.8e+02     281     298 ..     140     157 ..     133     176 .. 0.80
   2 ?    7.5   7.0   0.00095         1     362     395 ..     475     506 ..     437     523 .. 0.55

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.74
       Nop14 281 erLeklEeeRlkRMrgee 298
                 + Le lE +Rlk Mr + 
  EEA23042.1 140 KTLEDLEVDRLKEMRSAT 157
                 579***********9873 PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.00095
       Nop14 362 veseseeeeeeeeedeeeeedeeeee.eeeededd 395
                  +++s++e   eeedeee+++++ ee eee+dedd
  EEA23042.1 475 RNKKSDSE---EEEDEEEDSENSGEEsEEESDEDD 506
                 22222221...122222111111111111112111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (581 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1289  (0.0718947); expected 358.6 (0.02)
Passed bias filter:                      896  (0.0499749); expected 358.6 (0.02)
Passed Vit filter:                       156  (0.00870099); expected 17.9 (0.001)
Passed Fwd filter:                        19  (0.00105974); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              17  [number of targets reported over threshold]
# CPU time: 0.83u 0.35s 00:00:01.18 Elapsed: 00:00:00.49
# Mc/sec: 3549.27
//
Query:       EEA23043.1  [L=197]
Description: 50S ribosomal protein L12 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      9e-20   70.8   6.3    2.8e-18   66.0   4.6    2.3  2  Ribosomal_L12    Ribosomal protein L7/L12 C-terminal domain
      1e-11   44.3   9.0      1e-11   44.3   9.0    3.6  4  Ribosomal_L12_N  Ribosomal protein L7/L12 dimerisation domain
  ------ inclusion threshold ------
       0.12   12.1   1.0       0.35   10.7   0.2    2.0  2  SpoVIF           Stage VI sporulation protein F


Domain annotation for each model (and alignments):
>> Ribosomal_L12  Ribosomal protein L7/L12 C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.3   0.0    0.0085        51      13      38 ..      62      87 ..      55      91 .. 0.84
   2 !   66.0   4.6   4.7e-22   2.8e-18       1      65 [.     130     195 ..     130     197 .] 0.97

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.0085
                   HHHHHHHHHHH---HHHHHHHHTTTT CS
  Ribosomal_L12 13 iaVIKaVreitglgLkeaKdlVeaap 38
                    +++ +V +i +l L e  dlV ++ 
     EEA23043.1 62 PKIVQIVDQISQLTLLETADLVASLK 87
                   578999****************8865 PP

  == domain 2  score: 66.0 bits;  conditional E-value: 4.7e-22
                    EEEEEEE-TT-.HHHHHHHHHHHH---HHHHHHHHTTTTSTEEEEE-HHHHHHHHHHHHCTT-EEE CS
  Ribosomal_L12   1 fdViLksagak.KiaVIKaVreitglgLkeaKdlVeaapkvvkegvskeeAeeikkkLeeaGAeve 65 
                    f++ L+s++a+ K +VIK+++++ gl+L+++K++Ve++pk +ke+v+k+e+e+i ++L+  GA+v 
     EEA23043.1 130 FNLKLESFEAAsKPKVIKEIKSMLGLSLVDSKKFVESVPKLLKENVAKDECEKIIETLKGLGAKVV 195
                    899******999****************************************************96 PP

>> Ribosomal_L12_N  Ribosomal protein L7/L12 dimerisation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.1      0.57   3.4e+03      32      35 ..      56      59 ..      48      61 .. 0.56
   2 !   44.3   9.0   1.7e-15     1e-11       1      45 [.      63     112 ..      63     127 .. 0.77
   3 ?   -1.7   0.0      0.42   2.5e+03       5      12 ..     145     152 ..     142     159 .. 0.63
   4 ?   -1.3   0.0       0.3   1.8e+03       3      12 ..     181     190 ..     180     190 .. 0.89

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 0.57
                     HHHH CS
  Ribosomal_L12_N 32 AAAP 35
                     AAAP
       EEA23043.1 56 AAAP 59
                     1122 PP

  == domain 2  score: 44.3 bits;  conditional E-value: 1.7e-15
                      HHHHHHHHHHTSBHHHHHHHHHHHHHHTTHHHHHHHHHH....H...HHHH CS
  Ribosomal_L12_N   1 kieeiieaikeltvLElseLvkalEekFGVsAAAPvava...aa...aaaa 45 
                      ki +i+++i++lt+LE+++Lv  l++++++++  Pv+++   a+   a+aa
       EEA23043.1  63 KIVQIVDQISQLTLLETADLVASLKSRLNIPDL-PVGGFavaAGpggAGAA 112
                      6789***************************97.54444442333222222 PP

  == domain 3  score: -1.7 bits;  conditional E-value: 0.42
                      HHHHHHTS CS
  Ribosomal_L12_N   5 iieaikel 12 
                      +i++ik++
       EEA23043.1 145 VIKEIKSM 152
                      55555554 PP

  == domain 4  score: -1.3 bits;  conditional E-value: 0.3
                      HHHHHHHHTS CS
  Ribosomal_L12_N   3 eeiieaikel 12 
                      e+iie +k+l
       EEA23043.1 181 EKIIETLKGL 190
                      89*****987 PP

>> SpoVIF  Stage VI sporulation protein F
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.2   0.0      0.29   1.7e+03      33      44 ..      64      75 ..      61      78 .. 0.77
   2 ?   10.7   0.2   5.8e-05      0.35      34      61 ..     161     188 ..     141     193 .. 0.92

  Alignments for each domain:
  == domain 1  score: -1.2 bits;  conditional E-value: 0.29
      SpoVIF 33 lRqlikqvskla 44
                + q+++q+s+l+
  EEA23043.1 64 IVQIVDQISQLT 75
                557888888886 PP

  == domain 2  score: 10.7 bits;  conditional E-value: 5.8e-05
      SpoVIF  34 Rqlikqvsklankpvskekedkivkaiv 61 
                 ++++++v kl++++v k++ +ki+++ +
  EEA23043.1 161 KKFVESVPKLLKENVAKDECEKIIETLK 188
                 689*********************9865 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (197 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       788  (0.0439511); expected 358.6 (0.02)
Passed bias filter:                      555  (0.0309554); expected 358.6 (0.02)
Passed Vit filter:                        48  (0.00267723); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.32s 00:00:00.82 Elapsed: 00:00:00.48
# Mc/sec: 1233.20
//
Query:       EEA23044.1  [L=151]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    6.4e-12   45.8   0.0    1.3e-11   44.8   0.0    1.5  1  Glyoxalase    Glyoxalase/Bleomycin resistance protein/Dioxyge
    2.6e-05   24.5   0.0    3.4e-05   24.1   0.0    1.1  1  Glyoxalase_4  Glyoxalase/Bleomycin resistance protein/Dioxyge
     0.0016   18.4   0.0       0.15   12.0   0.0    2.1  2  Glyoxalase_2  Glyoxalase-like domain
  ------ inclusion threshold ------
       0.11   13.2   0.0        1.2   10.0   0.0    2.1  1  Glyoxalase_6  Glyoxalase-like domain
       0.14   12.3   0.0        1.1    9.3   0.0    1.9  1  Glyoxalase_3  Glyoxalase-like domain
       0.16   11.6   0.0       0.24   11.0   0.0    1.2  1  PrpR_N        Propionate catabolism activator


Domain annotation for each model (and alignments):
>> Glyoxalase  Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.8   0.0   4.2e-15   1.3e-11       2     128 .]      21     146 ..      20     146 .. 0.82

  Alignments for each domain:
  == domain 1  score: 44.8 bits;  conditional E-value: 4.2e-15
                 EEEEEEEESHHHHHHHHHHHHHTSEEEEEEEEEESTEEEEEEEEE.TTTSEEEEEEEECCTTSCTHHCCBSCTSEEEEEEEEEHCHHHHHHHHHHHTTG CS
  Glyoxalase   2 idhvallvgdleksldFYtkvLGfklvkktdnteeteglriaffh.aggghielvlneapsgaakhvkkieetvhhvafialdvedvgkaldrlkeagv 99 
                 +dh++l v+ +  s++FYt+vLG+     t    +t+++r+a +  + +  +  ++ne +++a +             + +l++edvg  l rlke+g+
  EEA23044.1  21 LDHLVLTVKSIPTSISFYTQVLGMAHQSFTSPSDPTSTPRHALLFgSQKINLHQAGNEFEPKAVTAL------PGTADLCFLTEEDVGVVLGRLKEKGI 113
                 89**********************8877777688888888876550455577778888888888888......566789999****************9 PP

                 EEEEEEECHHCTEEEEE....EEEETTSEEEEE CS
  Glyoxalase 100 kvvaepgrhyfgalysf....yfrDpdGillei 128
                 +v ++ +  + ++  s+    y+rDpdG+l+ei
  EEA23044.1 114 EVLEGGKVVKRTGARSAlrsvYVRDPDGNLIEI 146
                 999987766666666666777***********8 PP

>> Glyoxalase_4  Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.0   1.1e-08   3.4e-05       1     105 [.      22     127 ..      22     130 .. 0.78

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 1.1e-08
                   EEEEEE-S-HHHHHHHHHH.TT-EESS--E..EETTTTEEEEEEEETTEEEEEEEESSTT-THHH.TS-EEEEEEEEES.-HHHHHHHHCTTTEEEE CS
  Glyoxalase_4   1 dQigivVeDleaavarfsallGvgpwqryr.depqevdlafallgsgsvqieLieplegpeflae.hgeglhhlaywvd.dldaavarleeqGfevv 94 
                   d++ + V+++   + +++++lG+      + ++p++   + +l gs   +i L ++ ++ e+ a    +g   l++ ++ d+  ++ rl+e+G+ev+
    EEA23044.1  22 DHLVLTVKSIPTSISFYTQVLGMAHQSFTSpSDPTSTPRHALLFGS--QKINLHQAGNEFEPKAVtALPGTADLCFLTEeDVGVVLGRLKEKGIEVL 116
                   69999*****************975544441444444444455555..3999999999887766679**********965***************** PP

                   EEEE-GGGTT- CS
  Glyoxalase_4  95 qkgvragaagr 105
                   + g  + + g 
    EEA23044.1 117 EGGKVVKRTGA 127
                   99977766665 PP

>> Glyoxalase_2  Glyoxalase-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.3   0.0     0.012        36       4      24 ..      24      44 ..      21      48 .. 0.87
   2 !   12.0   0.0   4.9e-05      0.15      68     115 ..      97     148 ..      82     150 .. 0.73

  Alignments for each domain:
  == domain 1  score: 4.3 bits;  conditional E-value: 0.012
                  ---EES-HHHHHHHHHHTT-- CS
  Glyoxalase_2  4 illvvkdieeskkFYedvlel 24
                   +l+vk i +s +FY +vl +
    EEA23044.1 24 LVLTVKSIPTSISFYTQVLGM 44
                  6899**************975 PP

  == domain 2  score: 12.0 bits;  conditional E-value: 4.9e-05
                   EES-HHHHHHHH..GGGS-EEEEEEE.-TTS-....EEEEEE-TT--EEEEEE CS
  Glyoxalase_2  68 evedvdaflqklkeaeniellhelke.kpWgq....rvirfyDpDkhiiEige 115
                    +edv  +l +lke++ ie+l   k+ k  g     r +++ DpD+++iEi++
    EEA23044.1  97 TEEDVGVVLGRLKEKG-IEVLEGGKVvKRTGArsalRSVYVRDPDGNLIEISN 148
                   5789999999998887.99987655413333311227899***********97 PP

>> Glyoxalase_6  Glyoxalase-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   0.0   0.00039       1.2       4     104 ..      26     144 ..      23     147 .. 0.50

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 0.00039
  Glyoxalase_6   4 ldaadpaalaaFwaaalgweveree......aaledpegvgpaaedaatllfqrvpe.................paknrvHldlav.edld...... 70 
                   l ++   + + F+ ++lg+  ++        +            +    llf+  +                  p+     l + + ed+       
    EEA23044.1  26 LTVKSIPTSISFYTQVLGMAHQSFTspsdptS------------TPRHALLFGSQKInlhqagnefepkavtalPG--TADLCFLTeEDVGvvlgrl 108
                   55666667788888888888888773322220............22333444433333443333555544443321..2333333334444222222 PP

  Glyoxalase_6  71 .aevarlvalGArvlreprdgthgr..vlaDPeGneF 104
                    ++  +++  G++v+++  ++ + r   ++DP+Gn  
    EEA23044.1 109 kEKGIEVL-EGGKVVKRTGARSALRsvYVRDPDGNLI 144
                   12222222.36777777777766669999*****976 PP

>> Glyoxalase_3  Glyoxalase-like domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.3   0.0   0.00038       1.1       1     113 [.      21     128 ..      21     146 .. 0.68

  Alignments for each domain:
  == domain 1  score: 9.3 bits;  conditional E-value: 0.00038
  Glyoxalase_3   1 lDHvvlavpdleeaaarfarrlGftvtpggehp.glgtaNalvmfgdgYlEllavdpeapaperprlfgldrlakgeglhtlalrt.ddidataarl 95 
                   lDH+vl v+++ + ++ +++ lG+  +     + ++ t  + + fg + ++l +  +e ++         +++++ +g  +l++ t +d+  +  rl
    EEA23044.1  21 LDHLVLTVKSIPTSISFYTQVLGMAHQSFTSPSdPTSTPRHALLFGSQKINLHQAGNEFEP---------KAVTALPGTADLCFLTeEDVGVVLGRL 108
                   8999999999999999999999998875544442566666777777778887776444443.........344556888888888767888888888 PP

  Glyoxalase_3  96 raaGvd..eagrrvrpdggd 113
                   +++G++  e g+ v+  g +
    EEA23044.1 109 KEKGIEvlEGGKVVKRTGAR 128
                   88888874434433555554 PP

>> PrpR_N  Propionate catabolism activator
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.0     8e-05      0.24     103     143 ..      96     136 ..      92     142 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 8e-05
      PrpR_N 103 nseeeaeaavkelkaegvevvvGdgvvadlAekaGlksvll 143
                  +ee++  ++ +lk++g+ev+ G++vv+++ ++  l+sv +
  EEA23044.1  96 LTEEDVGVVLGRLKEKGIEVLEGGKVVKRTGARSALRSVYV 136
                 6899*************************999999998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (151 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       335  (0.0186848); expected 358.6 (0.02)
Passed bias filter:                      308  (0.0171789); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.48u 0.29s 00:00:00.77 Elapsed: 00:00:00.48
# Mc/sec: 951.97
//
Query:       EEA23045.1  [L=455]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      2e-05   25.1   0.7       0.34   11.7   0.0    2.7  2  Sel1            Sel1 repeat
     0.0031   17.7   3.0        4.4    7.7   0.0    4.7  5  TPR_12          Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.038   13.6   0.0      0.059   13.0   0.0    1.2  1  HMG_CoA_synt_C  Hydroxymethylglutaryl-coenzyme A synthase C t
      0.073   13.3   2.0        3.6    7.9   0.4    2.9  3  ANAPC3          Anaphase-promoting complex, cyclosome, subuni
       0.21   12.1   1.7        7.7    7.1   0.3    3.6  5  TPR_19          Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> Sel1  Sel1 repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.7   0.0   9.5e-05      0.34       2      27 ..     331     357 ..     330     363 .. 0.80
   2 !   11.2   0.2   0.00013      0.47      23      38 .]     379     394 ..     374     394 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 9.5e-05
        Sel1   2 eAmyrLG.mfylylnGlgvpkDpekAi 27 
                 eA+yrLG ++yl  +G    +D++ A 
  EEA23045.1 331 EACYRLGnYYYLISKGEVPSRDQRIAQ 357
                 8******99999999985555887775 PP

  == domain 2  score: 11.2 bits;  conditional E-value: 0.00013
        Sel1  23 pekAiewyekAAeqGd 38 
                 +++Ai wye+A ++Gd
  EEA23045.1 379 RRRAINWYEMASAHGD 394
                 579***********97 PP

>> TPR_12  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.7   0.0    0.0012       4.4      52      70 ..     222     240 ..     212     245 .. 0.87
   2 ?    4.4   0.0     0.012        45      51      67 ..     271     287 ..     266     289 .. 0.62
   3 ?    0.4   0.1      0.23   8.1e+02      46      61 ..     324     339 ..     318     340 .. 0.57
   4 ?   -1.3   0.0      0.75   2.7e+03      41      73 ..     359     391 ..     353     395 .. 0.77
   5 ?    0.2   0.0      0.26   9.2e+02      50      68 ..     400     417 ..     377     422 .. 0.63

  Alignments for each domain:
  == domain 1  score: 7.7 bits;  conditional E-value: 0.0012
      TPR_12  52 grlyralgryeeAlellee 70 
                 +++ r++gr+eeAl+l+++
  EEA23045.1 222 ADIARRWGRTEEALDLYRH 240
                 788999*********9986 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.012
      TPR_12  51 LgrlyralgryeeAlel 67 
                 L+++y +++r+eeA e+
  EEA23045.1 271 LADMYNEAERHEEADEM 287
                 56666666666666554 PP

  == domain 3  score: 0.4 bits;  conditional E-value: 0.23
      TPR_12  46 ttlrnLgrlyralgry 61 
                 +++ + g+++++lg+y
  EEA23045.1 324 AAMSGHGEACYRLGNY 339
                 4455555555555554 PP

  == domain 4  score: -1.3 bits;  conditional E-value: 0.75
      TPR_12  41 hpltattlrnLgrlyralgryeeAlelleeala 73 
                 hp  a++    +r +r+++  + A++++e a a
  EEA23045.1 359 HPKRAWIASWFARFFRKMDWRRRAINWYEMASA 391
                 777777777777777777777899999998865 PP

  == domain 5  score: 0.2 bits;  conditional E-value: 0.26
      TPR_12  50 nLgrlyralgryeeAlell 68 
                 nL+ l r+   + eAl+++
  EEA23045.1 400 NLAVLMRED-GHPEALDIF 417
                 555555444.445555544 PP

>> HMG_CoA_synt_C  Hydroxymethylglutaryl-coenzyme A synthase C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0   1.6e-05     0.059      71     142 ..      49     125 ..      30     133 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 1.6e-05
                     SEEEE--SSHHHHHHHHHHHHHHHHHH.S-HHHHHHH-GGGGGG.....TT--GGGGGT-HHHHHHHHHHHHHHHHH CS
  HMG_CoA_synt_C  71 dyvifhsPfcklvqkslarllynDflanassdkeeevkekleek.....ddlkldesltdkdlekallkiakelfkk 142
                        i  sP +k v+k+++r+l n   +++ +++ +evk+++e++     + ++  + +  k   k++l+i + l ++
      EEA23045.1  49 RGFIRKSPAAKNVNKGYGRILNNTVPTEQWQKNYHEVKTRFEKNyksiySMVQSSDLIAGKITPKVFLEIGRRLVDQ 125
                     567789***********************************998555545667777778888888888887776665 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.0     0.024        86      15      49 ..     207     241 ..     200     246 .. 0.67
   2 ?    7.9   0.4     0.001       3.6       6      72 ..     256     339 ..     253     340 .. 0.79
   3 ?   -2.1   0.0       1.3   4.6e+03      26      58 ..     366     398 ..     354     402 .. 0.67

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.024
                 HH.HHH--HHHHHHHHHHHHHTT-HHHHHHHHHCT CS
      ANAPC3  15 llaaetespedayllAlclylngqykrAyellrka 49 
                  la+e+e+p +++  A    + g+ ++A++l+r +
  EEA23045.1 207 KLAYEKEDPRALMVWADIARRWGRTEEALDLYRHL 241
                 33467777777777777777777777777777665 PP

  == domain 2  score: 7.9 bits;  conditional E-value: 0.001
                 HHHHHHHHHHH...........HHH--HHHHHHH.HHHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHH.....HHHHHTT-H CS
      ANAPC3   6 knAiflaerll..........aaetespedayll.AlclylngqykrAyellrka.klnskslgcrylfA.....qcllkLkky 72 
                 +++ f ++             +ae++ + d +++ +  +y++ q    y +lrk  +  ++ ++c +++A     ++++ L++y
  EEA23045.1 256 DDITFRGDYKApwriladmynEAERHEEADEMMKvGALHYRDPQALVTYAYLRKEkDDWESYEQCMLVAAmsghgEACYRLGNY 339
                 55555555555555555555568999999999988********************77777777898888899999999999998 PP

  == domain 3  score: -2.1 bits;  conditional E-value: 1.3
                 HHHHHHHHHHTT-HHHHHHHHHCTSHHHC-HHH CS
      ANAPC3  26 ayllAlclylngqykrAyellrkaklnskslgc 58 
                 a ++A  + ++    rA+++++ a   + s+g 
  EEA23045.1 366 ASWFARFFRKMDWRRRAINWYEMASAHGDSEGT 398
                 677888888888888999998877555555555 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.0   0.1     0.088   3.1e+02      16      54 ..     207     244 ..     202     255 .. 0.79
   2 ?    7.1   0.3    0.0022       7.7      23      61 ..     263     300 ..     229     306 .. 0.81
   3 ?   -3.9   0.0         5   1.8e+04      30      41 ..     328     339 ..     322     340 .. 0.57
   4 ?   -2.2   0.0       1.8   6.4e+03      16      34 ..     354     372 ..     353     376 .. 0.82
   5 ?   -1.5   0.0         1   3.8e+03       6      16 ..     409     419 ..     380     426 .. 0.55

  Alignments for each domain:
  == domain 1  score: 2.0 bits;  conditional E-value: 0.088
      TPR_19  16 qalqedpknaearllLAeallalgqldeAealLdalpee 54 
                 + l+++ ++++a++  A++    g+++eA +l   l ++
  EEA23045.1 207 K-LAYEKEDPRALMVWADIARRWGRTEEALDLYRHLNDM 244
                 4.5778899999999999999999999999987776665 PP

  == domain 2  score: 7.1 bits;  conditional E-value: 0.0022
      TPR_19  23 knaearllLAeallalgqldeAealLdalpeedpddary 61 
                 ++ + +  LA+ + ++ + +eA ++++   ++++d +++
  EEA23045.1 263 DYKAPWRILADMYNEAERHEEADEMMKVGALHYRD-PQA 300
                 56677777**************************9.654 PP

  == domain 3  score: -3.9 bits;  conditional E-value: 5
      TPR_19  30 lLAeallalgql 41 
                 +  ea++ lg++
  EEA23045.1 328 GHGEACYRLGNY 339
                 445566666654 PP

  == domain 4  score: -2.2 bits;  conditional E-value: 1.8
      TPR_19  16 qalqedpknaearllLAea 34 
                 ++ q+ pk a+++ + A+ 
  EEA23045.1 354 RIAQKHPKRAWIASWFARF 372
                 6789999999999999985 PP

  == domain 5  score: -1.5 bits;  conditional E-value: 1
      TPR_19   6 dyaeAlalleq 16 
                  + eAl+++++
  EEA23045.1 409 GHPEALDIFSR 419
                 33445555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (455 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       529  (0.0295053); expected 358.6 (0.02)
Passed bias filter:                      407  (0.0227007); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.58u 0.29s 00:00:00.86 Elapsed: 00:00:00.47
# Mc/sec: 2927.81
//
Query:       EEA23046.1  [L=441]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.9e-57  195.1   0.8    1.9e-57  195.1   0.8    2.5  2  Velvet    Velvet factor


Domain annotation for each model (and alignments):
>> Velvet  Velvet factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.2   1.5     0.043   7.8e+02      75     115 ..      74     105 ..      26     175 .. 0.52
   2 !  195.1   0.8   1.1e-61   1.9e-57       2     242 ..     187     417 ..     186     424 .. 0.82

  Alignments for each domain:
  == domain 1  score: -0.2 bits;  conditional E-value: 0.043
                 .---------.-------------.....----------------- CS
      Velvet  75 sssasssisseasssssqsseess.....sspksqassaessapss 115
                 +ss+ss+ s             ss     +    +++s++s++p s
  EEA23046.1  74 PSSSSSQYSI-----------PSSsifssV---YPDHSSQSTYPRS 105
                 2222222222...........111221111...1111111111111 PP

  == domain 2  score: 195.1 bits;  conditional E-value: 1.1e-61
                 EEEEEE---EEE---SS-S-----BS--EEEEEEEETTT-SB--GGG---TTEEEEEEEEETT...SSSB--EE--.---------.------------ CS
      Velvet   2 sLevvQqPkrARmCgfgdkdrrpidPppvvqLrvtdaetnsevdveeldssffvvtvdLwsed...gtkevnlvkssssasssisseasssssqssees 97 
                 +L+++QqP+++R+C +g+kdrr idPpp++qL+vtd++++s +d++ l++s+f v + L+s+     + e  lv+ss+  ++  ++++  ++s+++ + 
  EEA23046.1 187 RLHIRQQPIATRACSAGEKDRRTIDPPPILQLLVTDFRPDSRTDLAILQNSRFAVACLLYSVGkpgPDGEEVLVHSSQVVEATRRRQRDDGRSHNTFR- 284
                 8************************************************************6656433444454443333222222122222222211. PP

                 ----------------------------------------------EESEEE--EEE-EE...EE-TT...............--EEEEEE---EEESS CS
      Velvet  98 ssspksqassaessapsssaapsaqeekekkeatlssssnqasskltrnLiGslvasafr...lkdpe...............dkpgifFvfqDLSVRt 178
                                 +          ++ ++++ +++ +q++++++++L+G++ +s+f+   ++dpe                +p++fFvf DLSVRt
  EEA23046.1 285 ----------------V----------DSRTTQRINEQLDQSDQRPVQILSGRTYVSPFHtpyDPDPEtapchhyqqqhhntkPTPATFFVFADLSVRT 357
                 ................1..........22345566778889999****************97777777**********9886545************** PP

                 -EEEEEEEEEEE-B-S--B--S..SEEEEEEEEE---EEEE-TTT--------HHHHHHHHTT- CS
      Velvet 179 eGtFrLrfrlvnvgaeavaveekegsapvlaevfSdpFtVysakkFpGvlesTaLskalakqGi 242
                 +Gt+rL+frl+++g      +e+++ +p+lae+fSdpF+Vys+k+FpG++ s+aL+ +l + G+
  EEA23046.1 358 AGTYRLKFRLMDWGL----AQETGKPQPILAEIFSDPFKVYSSKDFPGMRASSALTWSLRNMGM 417
                 ***************....89999**************************************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (441 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       341  (0.0190195); expected 358.6 (0.02)
Passed bias filter:                      205  (0.011434); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.51u 0.27s 00:00:00.78 Elapsed: 00:00:00.46
# Mc/sec: 2880.82
//
Query:       EEA23047.1  [L=611]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
  ------ inclusion threshold ------
       0.66   10.3   3.4         36    4.8   0.0    3.6  3  Cohesin_HEAT  HEAT repeat associated with sister chromatid co


Domain annotation for each model (and alignments):
>> Cohesin_HEAT  HEAT repeat associated with sister chromatid cohesion
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.1    0.0078   1.4e+02      18      31 ..     153     166 ..     145     167 .. 0.77
   2 ?    0.5   0.1     0.043   7.8e+02      23      33 ..     329     339 ..     326     339 .. 0.89
   3 ?    4.8   0.0     0.002        36       9      34 ..     385     410 ..     384     411 .. 0.93

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.0078
                   HHHHHHHHHHHSS- CS
  Cohesin_HEAT  18 evldtiarrltDss 31 
                   +vl t+++rl D +
    EEA23047.1 153 SVLTTVISRLKDAE 166
                   79**********76 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.043
                   HHHHHHSS-HH CS
  Cohesin_HEAT  23 iarrltDssps 33 
                   i+++  D+sps
    EEA23047.1 329 ISKCVKDTSPS 339
                   99********8 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.002
                   H-GGGGGSHHHHHHHHHHHHSS-HHH CS
  Cohesin_HEAT   9 kdpsiLsapevldtiarrltDsspsV 34 
                   k+++++++ ++ +++ +r +D+ +sV
    EEA23047.1 385 KFDDGMTDFSIVQSLLARINDNGTSV 410
                   7899999999**************99 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (611 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       444  (0.0247643); expected 358.6 (0.02)
Passed bias filter:                      425  (0.0237046); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.62u 0.29s 00:00:00.90 Elapsed: 00:00:00.46
# Mc/sec: 4018.13
//
Query:       EEA23048.1  [L=291]
Description: SYF2 splicing factor family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.2e-58  196.6  16.7    3.2e-58  196.6  16.7    2.0  2  SYF2      SYF2 splicing factor
  ------ inclusion threshold ------
        2.8    7.2   6.5          5    6.3   0.2    2.2  2  DUF4932   Domain of unknown function (DUF4932)


Domain annotation for each model (and alignments):
>> SYF2  SYF2 splicing factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.3   1.2     0.091   8.1e+02      30      63 ..      32      58 ..       5     102 .. 0.46
   2 !  196.6  16.7   3.6e-62   3.2e-58       1     159 []     110     286 ..     110     286 .. 0.98

  Alignments for each domain:
  == domain 1  score: 0.3 bits;  conditional E-value: 0.091
        SYF2 30 eknedagfsdyedaayrkYkkqlkelkpdleaYe 63
                e +e+        +a  + +   ++ +  le+++
  EEA23048.1 32 EDSEQL-------QASSSNDGASSKAQDRLERFK 58
                111111.......111111222222222233333 PP

  == domain 2  score: 196.6 bits;  conditional E-value: 3.6e-62
        SYF2   1 ekgedlerkkalewsaeeaekwekkkkkk.eknedagfsdyedaayrkYkkqlkelkpdleaYekqkekaleka................savsk.eaf 81 
                 e+ged+erk+a++w++ee+e+w+++++kk ++++d++f+dy+++a++ Yk+ql+e++ dl++Yek+k +a e+a                +av++ ++f
  EEA23048.1 110 EAGEDFERKRAWDWTIEESERWDRRMEKKqRHRDDVAFQDYRQDARKVYKRQLREMQTDLDTYEKEKIAAVERAaasggleivetddgelVAVDRnGTF 208
                 689**************************99*****************************************99****************8888889** PP

        SYF2  82 yrtantlsladhkpseeavdrlveklekqeekrkkfsrrrkedeegdvtYINerNkkFNkklerfYdkytaeIrenLE 159
                 y+ta++++++++kp+++avdrlv++l+k+ee+r k++r+r+ +e++dvtYINe+Nk+FN+kl+rfYdkyt+eIr+++E
  EEA23048.1 209 YSTADSTDFTENKPDRAAVDRLVSDLRKAEEVRLKKRRDRRGEEDADVTYINEKNKQFNQKLARFYDKYTKEIRDSFE 286
                 *****************************************************************************9 PP

>> DUF4932  Domain of unknown function (DUF4932)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.3   1.6    0.0045        40      85     146 ..     112     174 ..     108     180 .. 0.73
   2 ?    6.3   0.2   0.00056         5      79     115 ..     239     275 ..     226     285 .. 0.91

  Alignments for each domain:
  == domain 1  score: 3.3 bits;  conditional E-value: 0.0045
     DUF4932  85 qsDlekkskldnrwteeeleefvrllk...efyreskFkdFytanaelykdvlenlkkalekqdv 146
                 ++D+e k + d  wt+ee e + r ++   +   + +F+d+ +  +++yk  l +++ +l+ +++
  EEA23048.1 112 GEDFERKRAWD--WTIEESERWDRRMEkkqRHRDDVAFQDYRQDARKVYKRQLREMQTDLDTYEK 174
                 56777777776..555555555555540004455789*******************999998875 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.00056
     DUF4932  79 evkLspqsDlekkskldnrwteeeleefvrllkefyr 115
                 ev+L++  D   +++ d  +++e+ ++f++ l +fy 
  EEA23048.1 239 EVRLKKRRDRRGEEDADVTYINEKNKQFNQKLARFYD 275
                 7999999****************************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (291 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1947  (0.108595); expected 358.6 (0.02)
Passed bias filter:                      456  (0.0254337); expected 358.6 (0.02)
Passed Vit filter:                        40  (0.00223102); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.58u 0.27s 00:00:00.85 Elapsed: 00:00:00.47
# Mc/sec: 1861.18
//
Query:       EEA23049.1  [L=284]
Description: SYF2 splicing factor family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.3e-51  175.1  14.3    1.3e-51  175.1  14.3    2.0  2  SYF2         SYF2 splicing factor
  ------ inclusion threshold ------
        2.1    7.6   6.4        4.1    6.6   0.2    2.1  2  DUF4932      Domain of unknown function (DUF4932)
        5.5    6.3   8.1       0.97    8.8   1.8    2.2  2  RIBIOP_C     40S ribosome biogenesis protein Tsr1 and BMS1 C-


Domain annotation for each model (and alignments):
>> SYF2  SYF2 splicing factor
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.4   1.2      0.13   7.8e+02      30      63 ..      32      58 ..       5     102 .. 0.46
   2 !  175.1  14.3   2.2e-55   1.3e-51       1     150 [.     110     277 ..     110     279 .. 0.98

  Alignments for each domain:
  == domain 1  score: 0.4 bits;  conditional E-value: 0.13
        SYF2 30 eknedagfsdyedaayrkYkkqlkelkpdleaYe 63
                e +e+        +a  + +   ++ +  le+++
  EEA23049.1 32 EDSEQL-------QASSSNDGASSKAQDRLERFK 58
                111111.......111121222222222233333 PP

  == domain 2  score: 175.1 bits;  conditional E-value: 2.2e-55
        SYF2   1 ekgedlerkkalewsaeeaekwekkkkkk.eknedagfsdyedaayrkYkkqlkelkpdleaYekqkekaleka................savsk.eaf 81 
                 e+ged+erk+a++w++ee+e+w+++++kk ++++d++f+dy+++a++ Yk+ql+e++ dl++Yek+k +a e+a                +av++ ++f
  EEA23049.1 110 EAGEDFERKRAWDWTIEESERWDRRMEKKqRHRDDVAFQDYRQDARKVYKRQLREMQTDLDTYEKEKIAAVERAaasggleivetddgelVAVDRnGTF 208
                 689**************************99*****************************************99****************8888889** PP

        SYF2  82 yrtantlsladhkpseeavdrlveklekqeekrkkfsrrrkedeegdvtYINerNkkFNkklerfYdky 150
                 y+ta++++++++kp+++avdrlv++l+k+ee+r k++r+r+ +e++dvtYINe+Nk+FN+kl+rfYdk 
  EEA23049.1 209 YSTADSTDFTENKPDRAAVDRLVSDLRKAEEVRLKKRRDRRGEEDADVTYINEKNKQFNQKLARFYDKV 277
                 *******************************************************************95 PP

>> DUF4932  Domain of unknown function (DUF4932)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   1.6    0.0064        39      85     146 ..     112     174 ..     108     180 .. 0.73
   2 ?    6.6   0.2   0.00069       4.1      79     116 ..     239     276 ..     226     283 .. 0.90

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.0064
     DUF4932  85 qsDlekkskldnrwteeeleefvrllk...efyreskFkdFytanaelykdvlenlkkalekqdv 146
                 ++D+e k + d  wt+ee e + r ++   +   + +F+d+ +  +++yk  l +++ +l+ +++
  EEA23049.1 112 GEDFERKRAWD--WTIEESERWDRRMEkkqRHRDDVAFQDYRQDARKVYKRQLREMQTDLDTYEK 174
                 56777777776..555555555555540004455789*******************999998875 PP

  == domain 2  score: 6.6 bits;  conditional E-value: 0.00069
     DUF4932  79 evkLspqsDlekkskldnrwteeeleefvrllkefyre 116
                 ev+L++  D   +++ d  +++e+ ++f++ l +fy +
  EEA23049.1 239 EVRLKKRRDRRGEEDADVTYINEKNKQFNQKLARFYDK 276
                 7999*******************************975 PP

>> RIBIOP_C  40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.9   0.5      0.04   2.4e+02       6      32 ..      47      73 ..      17      95 .. 0.79
   2 ?    8.8   1.8   0.00016      0.97       6      80 ..     108     183 ..     104     201 .. 0.80

  Alignments for each domain:
  == domain 1  score: 0.9 bits;  conditional E-value: 0.04
    RIBIOP_C  6 dvearerfakyrglkslrtsewdpken 32
                + +a++r+++ ++lk   +s  d + +
  EEA23049.1 47 SSKAQDRLERFKALKARAKSATDSNLK 73
                567888999999999999888876543 PP

  == domain 2  score: 8.8 bits;  conditional E-value: 0.00016
    RIBIOP_C   6 dvearerfakyrglksl..rtsewdpkenlpeeyarifefenfketkkrvlkealeeregvegGtyvrleiknvpee 80 
                 ++ea e f+++r+       ++ wd + ++++ +++ + f++++++ ++v+k++l  + ++  +ty + +i  v+++
  EEA23049.1 108 TEEAGEDFERKRAWDWTieESERWDRRMEKKQRHRDDVAFQDYRQDARKVYKRQLR-EMQTDLDTYEKEKIAAVERA 183
                 56788888888887654115678*****************************9888.67777788888777777654 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (284 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1792  (0.0999498); expected 358.6 (0.02)
Passed bias filter:                      409  (0.0228122); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.27s 00:00:00.79 Elapsed: 00:00:00.44
# Mc/sec: 1932.69
//
Query:       EEA23050.1  [L=288]
Description: hypothetical protein PMAA_096460 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      2e-06   27.8   0.0    1.9e-05   24.7   0.0    2.3  1  NAD_binding_10  NAD(P)H-binding
    1.3e-05   24.8   0.0    2.4e-05   23.9   0.0    1.4  1  Epimerase       NAD dependent epimerase/dehydratase family
     0.0021   17.1   0.0     0.0069   15.4   0.0    1.8  2  3Beta_HSD       3-beta hydroxysteroid dehydrogenase/isomerase
     0.0053   16.0   0.1      0.061   12.5   0.0    2.4  2  NAD_binding_4   Male sterility protein
     0.0063   15.6   0.0      0.042   12.9   0.0    2.1  2  RmlD_sub_bind   RmlD substrate binding domain
  ------ inclusion threshold ------
      0.013   15.0   0.0      0.028   13.9   0.0    1.5  1  adh_short       short chain dehydrogenase
      0.029   14.3   0.0      0.066   13.1   0.0    1.5  1  KR              KR domain


Domain annotation for each model (and alignments):
>> NAD_binding_10  NAD(P)H-binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.0   7.3e-09   1.9e-05       1     150 [.      10     211 ..      10     263 .. 0.78

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 7.3e-09
                     TTTSHHHHHHHHHHHHC-T-EEEEEETTHHHC.HHHH.......CTTTCEEEE--TT-CCHHHHHHTT-SEEEES-................... CS
  NAD_binding_10   1 GAtGkvGrllvkellargghevtalvRnpekl.aele.......aeeglevvegdvtdvedlaealkgadaVvsal................... 68 
                     G++G  G++++k++  r g+ev+ l R+ e   + +         ++ +e  ++d++++++ +  lk+a aVv ++                   
      EEA23050.1  10 GGSGFLGSRICKHASVR-GWEVVSLSRSGEPQwDTVTaskerpgWASDVEWAKADILKPSTYKPYLKDATAVVHSMgilleadykgvvsgkesii 103
                     9****************.5********955331333211122223469************************99998999888888775555555 PP

                     .......--TCCHHHH...................................HHHHHHHHHHCT--EEEEEEETTTTSGCGCHHHHHHHHCCHHHH CS
  NAD_binding_10  69 .......ggggkdeeg...................................aknivdaakeagvkRfvlvsaigvgdevpgefgewnkellkayl 121
                            +       +                                   a+++++    ++v  fv++sa+g       +       l ++y+
      EEA23050.1 104 sglqrafS-------StkrgtqdplnrgveeelrpqesdgqltyevmnrdtAIALAQESSFEHVPTFVYISAAGGA-----P------ILPSRYI 180
                     44444441.......0334455556666777788888899999999996656666666666889999999999855.....1......246799* PP

                     HHHHHHHHHHHHS..SSEEEEEEE-CEE-ST CS
  NAD_binding_10 122 aakraaeellras..gldwTivrpggLtdep 150
                       kr+ae ++ +s  +l   ++rpg+L d  
      EEA23050.1 181 STKREAESIISQSlpDLRSIFIRPGFLYDSS 211
                     ************888************9986 PP

>> Epimerase  NAD dependent epimerase/dehydratase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.9   0.0   9.4e-09   2.4e-05       2      71 ..       7      83 ..       6      92 .. 0.86

  Alignments for each domain:
  == domain 1  score: 23.9 bits;  conditional E-value: 9.4e-09
                EEETTTSHHHHHHHHHHHHCTSEEEEEES-STTTTCHHCHHC...........EEEE--TT-HHHHHHHHHHHT-SEEEE- CS
   Epimerase  2 lVtGatGfiGsalvkallekgyevigldrlssasntarledl...........elveldltdrsalerlfkeeqpdavihl 71
                +V+G++Gf+Gs ++k+   +g+ev+ l+r  + +       +           e+ ++d++++s  + ++k  +++av+h 
  EEA23050.1  7 VVAGGSGFLGSRICKHASVRGWEVVSLSRSGEPQWDTVT--AskerpgwasdvEWAKADILKPSTYKPYLK--DATAVVHS 83
                79****************************444433333..256999************************..79999996 PP

>> 3Beta_HSD  3-beta hydroxysteroid dehydrogenase/isomerase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.4   0.0   2.7e-06    0.0069       1      76 [.       7      86 ..       7     114 .. 0.81
   2 ?   -1.7   0.0      0.44   1.1e+03     144     158 ..     177     191 ..     147     215 .. 0.72

  Alignments for each domain:
  == domain 1  score: 15.4 bits;  conditional E-value: 2.7e-06
   3Beta_HSD  1 vvtGgaGFlGralvkeLvrleelkevrvlDlrespelleelskvnvkk.......viegDvtdkdkleealegvdvvihlasl 76
                vv Gg+GFlG++++k+   ++  +ev +l    +p++ ++++ ++ +          ++D+++ ++ +  l+++ +v+h  ++
  EEA23050.1  7 VVAGGSGFLGSRICKHASVRG--WEVVSLSRSGEPQW-DTVTASKERPgwasdveWAKADILKPSTYKPYLKDATAVVHSMGI 86
                79*************987777..99999998888888.66655555545666777999********************98776 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.44
   3Beta_HSD 144 daypesKalaEklvl 158
                 + y ++K+ aE ++ 
  EEA23050.1 177 SRYISTKREAESIIS 191
                 445566666666655 PP

>> NAD_binding_4  Male sterility protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0     0.078     2e+02       2      13 ..       9      20 ..       8      26 .. 0.86
   2 !   12.5   0.0   2.4e-05     0.061     172     237 ..     175     269 ..     110     280 .. 0.78

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.078
                   E-TTSHHHHHHH CS
  NAD_binding_4  2 TGaTGFLGkvLl 13
                    G++GFLG+++ 
     EEA23050.1  9 AGGSGFLGSRIC 20
                   7*******9885 PP

  == domain 2  score: 12.5 bits;  conditional E-value: 2.4e-05
                    CCCHHHHHHHHHHHHHHHHHHHH---EEEEEE-EEE-...............................-SSST---TTSHHHHHHHHHHHH-EEES CS
  NAD_binding_4 172 lpntYeqsKalaEklvrearrrsglpvvivRpsiitg...............................esktGwingsdlgirgllgliakgvlpe 236
                    lp  Y  +K +aE ++ +     +l+ + +Rp+ ++                                 s+t  + + d++++ ++ +ia g+ + 
     EEA23050.1 175 LPSRYISTKREAESIISQSL--PDLRSIFIRPGFLYDssrkftlpialggmigaevdavlggrlkslvGSMTEKPLKADVVAQAVVEAIADGTTSG 268
                    7899****************..89***********9967666666666666666666666666655555555555555555555666666655555 PP

                    - CS
  NAD_binding_4 237 i 237
                    +
     EEA23050.1 269 V 269
                    5 PP

>> RmlD_sub_bind  RmlD substrate binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.9   0.0   1.6e-05     0.042       2      49 ..       5      76 ..       4      85 .. 0.74
   2 ?   -0.2   0.0      0.17   4.2e+02     124     156 ..     178     212 ..     158     218 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.9 bits;  conditional E-value: 1.6e-05
                   EEEEESTTSHHHHHHHHHCTTTSEEEEEE-TT........................T--TTSHHHHHHHHHH CS
  RmlD_sub_bind  2 kilvtGanGqlGseLakqlaeeglevlaltre........................eldltdaeavaellke 49
                   +++v G++G lGs + k ++ +g+ev++l+r+                        ++d+ ++++ +  lk+
     EEA23050.1  5 RLVVAGGSGFLGSRICKHASVRGWEVVSLSRSgepqwdtvtaskerpgwasdvewaKADILKPSTYKPYLKD 76
                   799**************************9998886666666666666655555555555555555555555 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.17
                    HHHHHHHHHHHHHHHH-S..SEEEEEE-SEESSSS CS
  RmlD_sub_bind 124 vYGrtKlaGEqavlaagk..kalivRtswvygekg 156
                     Y  tK + E  + ++ +  + + +R + +y++++
     EEA23050.1 178 RYISTKREAESIISQSLPdlRSIFIRPGFLYDSSR 212
                    6889***********98855789999999998865 PP

>> adh_short  short chain dehydrogenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   1.1e-05     0.028       3      81 ..       6      87 ..       4      90 .. 0.88

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1.1e-05
                EEEESTTSHHHHHHHHHHHHTT-EEEEEESCHHHHHHHHHHHHHT...TSEEEEEE-TTTSHHHHHHHHHHHHHHHSSESEE CS
   adh_short  3 vlvtGassGIGraiakelakeGakvvvvdrseekleevakelkee...gakalaiqvDvtdreevealvekavkklgkldvL 81
                 +v G+s+ +G  i+k+   +G++vv ++rs e+   +++  ke    ++++  +++D+ + +  + ++++a + + ++ +L
  EEA23050.1  6 LVVAGGSGFLGSRICKHASVRGWEVVSLSRSGEPQWDTVTASKERpgwASDVEWAKADILKPSTYKPYLKDATAVVHSMGIL 87
                689999999*************************999999999998888899999999999999999999988877777666 PP

>> KR  KR domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   2.6e-05     0.066       4      76 ..       7      78 ..       5      93 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 2.6e-05
                EEETTTSHHHHHHHHHHHHHHS-EEEEE-SS..--HHHHHHHHHHHHTT-EEEE----TT-HHHHHHHHHHHH CS
          KR  4 litGGlGgLGlelarwlaekgarhlvllsRsaaadedskaliaelealgaevevvaaDvsdkdavealleeik 76
                +++GG G LG  ++++   +g  ++v lsRs++++ d  +  +e      +ve+++aD+ +++  + +l++++
  EEA23050.1  7 VVAGGSGFLGSRICKHASVRGW-EVVSLSRSGEPQWDTVTASKERPGWASDVEWAKADILKPSTYKPYLKDAT 78
                79**************999997.58999***8877777777777777788************99999998876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (288 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       304  (0.0169558); expected 358.6 (0.02)
Passed bias filter:                      274  (0.0152825); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.53u 0.30s 00:00:00.83 Elapsed: 00:00:00.50
# Mc/sec: 1748.99
//
Query:       EEA23051.1  [L=252]
Description: histone acetyltransferase subunit (Yaf9), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    7.7e-36  121.9   1.3    1.1e-35  121.4   1.3    1.3  1  YEATS       YEATS family
  ------ inclusion threshold ------
      0.034   13.3   0.2      0.059   12.5   0.2    1.3  1  M16C_assoc  Peptidase M16C associated


Domain annotation for each model (and alignments):
>> YEATS  YEATS family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  121.4   1.3   1.3e-39   1.1e-35       1      80 [.      42     122 ..      42     123 .. 0.98

  Alignments for each domain:
  == domain 1  score: 121.4 bits;  conditional E-value: 1.3e-39
       YEATS   1 thkWtvavrsaasddlsefikkVqFkLhetyanptrvvekpPFevtetGwGeFeiqikiffkpea.ekpltlehdLklhpe 80 
                 th+W+v+v++++ +d++++++kVqFkLhetya+ +r++e+pPFev etGwGeFeiqik++f+pe+ ekp+tl h Lklhp+
  EEA23051.1  42 THQWRVFVKGVNGEDITYWLRKVQFKLHETYAQSVRTIEQPPFEVAETGWGEFEIQIKLYFVPESnEKPQTLWHSLKLHPY 122
                 8**********99***************************************************99*************97 PP

>> M16C_assoc  Peptidase M16C associated
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.2   6.6e-06     0.059       3      48 ..     195     243 ..     194     248 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 6.6e-06
  M16C_assoc   3 PdeeleeekekeekerLaakkasls...eeekekiveetkeLkerQekp 48 
                 P + +++  e++e erL +  ++++   +eek+++ve++k L+e +e++
  EEA23051.1 195 PGNPYSKATEHAELERLGNAMKTVDqmiKEEKDRLVEREKRLAELKETE 243
                 6677899999999999998888777777*****************9987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (252 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       950  (0.0529868); expected 358.6 (0.02)
Passed bias filter:                      604  (0.0336884); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.40
# Mc/sec: 1867.61
//
Query:       EEA23052.1  [L=175]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.3e-16   59.8   8.8    3.9e-16   59.0   8.8    1.4  1  BC10      Bladder cancer-related protein BC10


Domain annotation for each model (and alignments):
>> BC10  Bladder cancer-related protein BC10
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   59.0   8.8   2.2e-20   3.9e-16       1      64 [.       1      55 [.       1      56 [. 0.98

  Alignments for each domain:
  == domain 1  score: 59.0 bits;  conditional E-value: 2.2e-20
        BC10  1 MfcLrflipvlllpvrsnrslvnaselfivlfligftvelkPcvycsiilgllikaicrpnlsd 64
                MfcLr+++p+l++p       +nas+lfi+ f++ +++ ++Pc+ycs +l++l++   ++ +sd
  EEA23052.1  1 MFCLRSWLPLLFIP-------TNASPLFILSFVVLTYILHRPCIYCSALLLILFTS--SCQWSD 55
                **************.......***********************************..****98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (175 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       417  (0.0232584); expected 358.6 (0.02)
Passed bias filter:                      306  (0.0170673); expected 358.6 (0.02)
Passed Vit filter:                        34  (0.00189637); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.37u 0.25s 00:00:00.62 Elapsed: 00:00:00.38
# Mc/sec: 1375.88
//
Query:       EEA23053.1  [L=295]
Description: export control protein CHS7-like, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
     2e-108  362.2   6.5   2.4e-108  361.9   6.5    1.0  1  Chs7        Chitin synthase export chaperone


Domain annotation for each model (and alignments):
>> Chs7  Chitin synthase export chaperone
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  361.9   6.5  1.3e-112  2.4e-108       1     283 [.       5     289 ..       5     292 .. 0.98

  Alignments for each domain:
  == domain 1  score: 361.9 bits;  conditional E-value: 1.3e-112
        Chs7   1 qfgdFdsiCrktalplCnllksskseteakegiepeCyargiel.antiifnlgsilihivalivtlililrvrskktAvGRkEillflllyllleile 98 
                 qfg+F+++Cr+++lp+Cnl+ +s++  +   g    C ++gi+l ++++++nlgsil++++a++++++l l +++k++AvGR+Ei+lfll+y++++i+e
  EEA23053.1   5 QFGNFHNFCRDSTLPVCNLFVPSNQPPNLAFG---GCALTGIQLsNGRYLGNLGSILAAFIAIVTCIFLFLLSERKRAAVGRREIQLFLLGYVIISICE 100
                 7**********************777766665...6********999**************************************************** PP

        Chs7  99 lvvdggviplsskvypyfvavqiglisatlwiLllnglvgfqlleDGtplSllllrlsslvlfivtflialdtfkswtaelsst.....ktiaLfvlly 192
                 ++++g + pl+++v++ f+av+i++isat wiLlln+lvgfqll+DGtplS++l+ +s++vlfi+t++ialdt++swt++++s+     ++i+L+vl++
  EEA23053.1 101 IFTVGAF-PLADNVRKGFSAVHIAAISATSWILLLNALVGFQLLDDGTPLSVGLFAGSATVLFIGTGYIALDTGFSWTGHFDSSlsgdnRNIGLYVLYL 198
                 *******.******************************************************************************************* PP

        Chs7 193 llnlvllvvyvvlqlilvlrvLeerwplgalllgvllfvigqvllyvlskkiCegvkhyidGlffetlcnllavmmvykfWdsiTeddlef 283
                 l++lv+l+++++l++ilvlrvL+er+pl++l++++llf+igq++ +v+s +iC+ ++++i+G+ffetl+  ++v+ v+ fW+siTedd++ 
  EEA23053.1 199 LFPLVCLCFFYILEVILVLRVLGERRPLIYLTAAALLFAIGQIFDFVISPHICNPINGKINGAFFETLFSFFSVVCVWLFWSSITEDDWPA 289
                 *****************************************************************************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (295 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       666  (0.0371465); expected 358.6 (0.02)
Passed bias filter:                      302  (0.0168442); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.46u 0.26s 00:00:00.72 Elapsed: 00:00:00.42
# Mc/sec: 2100.06
//
Query:       EEA23054.1  [L=272]
Description: dienelactone hydrolase family protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
      7e-29  100.9   0.0    8.5e-29  100.7   0.0    1.0  1  DLH            Dienelactone hydrolase family
  ------ inclusion threshold ------
      0.011   15.4   0.0      0.016   14.8   0.0    1.2  1  Peptidase_S15  X-Pro dipeptidyl-peptidase (S15 family)
      0.011   15.7   0.0       0.22   11.4   0.0    2.0  2  BAAT_C         BAAT / Acyl-CoA thioester hydrolase C terminal
      0.021   14.4   0.0      0.027   14.0   0.0    1.1  1  LIDHydrolase   Lipid-droplet associated hydrolase


Domain annotation for each model (and alignments):
>> DLH  Dienelactone hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  100.7   0.0   1.9e-32   8.5e-29      10     216 ..      35     253 ..      22     254 .. 0.90

  Alignments for each domain:
  == domain 1  score: 100.7 bits;  conditional E-value: 1.9e-32
         DLH  10 nakkpvvvviqeifGvndnikdiserlaeeGYvalaPdlYarqa......ldpndeaeaaraldelvskvaeekvlddlkaavaylksvpevstkkvgv 102
                 na++p+vvv+ ei+ v+  +++ ++++a +GY+  aP  Y           d+ + +++ +++ ++ +kv  ++  +d++ +v+yl s p +++++vg+
  EEA23054.1  35 NARFPGVVVFSEIYQVTGPVARFARQIAGQGYICAAPSSYHEFTgpealkYDV-EDTDKGNLW-KITKKV--QAYDEDASLSVDYLLSLP-TCNGRVGA 128
                 558**************9999*******************9888777753333.334455566.777777..888999999*********.******** PP

         DLH 103 vGfCmGGalalllaaevpevdaavafYG..........lspekeleeaakikapilalfgeeDefipadevekleealkaanvdlelkvYpgagHaFan 191
                 +G+C+GG la+  a  + +v+aav ++            + +  l++a +i + ++++fg++D+++pa+ ++ ++++l +++v + +   + a+HaF +
  EEA23054.1 129 TGMCLGGHLAYRCALDQ-RVKAAVCYFAtdihsatlgeGKSDDSLKRAGDIRGELIMIFGKNDNHVPAEGRDLIRKTLHDKGVLFSFYEVAWAQHAFIR 226
                 **************999.8*****************9999999********************************************99999******* PP

         DLH 192 dsre..syneeaaedawervlelfkqv 216
                 d+ +   y+++  +  +e +lelf++ 
  EEA23054.1 227 DELSkgRYDPAISKVCFEMLLELFNRT 253
                 *988789****************9985 PP

>> Peptidase_S15  X-Pro dipeptidyl-peptidase (S15 family)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.8   0.0   3.5e-06     0.016      84     130 ..     107     151 ..      95     168 .. 0.78

  Alignments for each domain:
  == domain 1  score: 14.8 bits;  conditional E-value: 3.5e-06
                    HHHHHHHHHHHHCTTEEEEEEEEEECHHHHHHHHHCTT--TTEEEEE CS
  Peptidase_S15  84 edgadvidWlakqpwsnGkVgmtGiSYlGttqllaaatgvpalkaiv 130
                    ed++  +d l   p +nG+Vg+tG+  +G +++  a ++  ++ka+v
     EEA23054.1 107 EDASLSVDYLLSLPTCNGRVGATGMCLGGHLAYRCALDQ--RVKAAV 151
                    6777789999999********************999854..344433 PP

>> BAAT_C  BAAT / Acyl-CoA thioester hydrolase C terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.4   0.0     5e-05      0.22      10      54 ..     113     155 ..     110     164 .. 0.85
   2 ?    2.2   0.0     0.033   1.5e+02     101     132 ..     165     196 ..     156     210 .. 0.83

  Alignments for each domain:
  == domain 1  score: 11.4 bits;  conditional E-value: 5e-05
                 HHHHHCSTTB--SSEEEEEETHHHHHHHHHHHHSSSEEEEEEES- CS
      BAAT_C  10 inyllrhpkvkkdkigllGiSkGgelalllasflkkisavvling 54 
                 ++yll+ p+++  ++g  G++ Gg la   a   + ++a+v++ +
  EEA23054.1 113 VDYLLSLPTCN-GRVGATGMCLGGHLAYRCALD-QRVKAAVCYFA 155
                 79*********.99*************987743.58999999866 PP

  == domain 2  score: 2.2 bits;  conditional E-value: 0.033
                 TGGGCCCB--GGG--SEEEEEEETT-SSS-HH CS
      BAAT_C 101 eklaekalipvekakgpillvvgedDknwpSk 132
                 e++++++l ++++++g+++++ g++D+ +p++
  EEA23054.1 165 EGKSDDSLKRAGDIRGELIMIFGKNDNHVPAE 196
                 566778888999***************99986 PP

>> LIDHydrolase  Lipid-droplet associated hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0     6e-06     0.027     224     266 .]     179     225 ..     145     225 .. 0.79

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 6e-06
  LIDHydrolase 224 ka.lvfyfgkkDhWvpeetrdelkellge..eklevde.kgipHaFv 266
                   +  l+++fgk+D+ vp e rd ++++l++    +++ e   ++HaF+
    EEA23054.1 179 RGeLIMIFGKNDNHVPAEGRDLIRKTLHDkgVLFSFYEvAWAQHAFI 225
                   336**************************66666666669999**96 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (272 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       275  (0.0153383); expected 358.6 (0.02)
Passed bias filter:                      268  (0.0149478); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.45
# Mc/sec: 1798.82
//
Query:       EEA23055.1  [L=574]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    2.6e-47  161.5  47.1      1e-45  156.3  47.1    2.3  1  MFS_1       Major Facilitator Superfamily
    7.5e-14   51.1  24.2    9.5e-14   50.7  24.2    1.1  1  TRI12       Fungal trichothecene efflux pump (TRI12)
    3.1e-11   42.8   6.7    3.1e-11   42.8   6.7    2.4  2  Sugar_tr    Sugar (and other) transporter
    0.00018   20.5  23.9      0.015   14.2   3.2    2.3  2  MFS_1_like  MFS_1 like family
     0.0074   16.0   0.5     0.0074   16.0   0.5    3.4  3  PQ-loop     PQ loop repeat
  ------ inclusion threshold ------
       0.29   10.6   0.0       0.29   10.6   0.0    3.1  3  DUF1129     Protein of unknown function (DUF1129)


Domain annotation for each model (and alignments):
>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  156.3  47.1   3.3e-49     1e-45       2     352 ..      30     428 ..      29     429 .. 0.87

  Alignments for each domain:
  == domain 1  score: 156.3 bits;  conditional E-value: 3.3e-49
       MFS_1   2 llaaflsalarsilgpalplalaedlgispseigllltlyalgaavaslplGrlsdrfGrrrvlllglllfalg.lllllfasslwlllvlrvlqGlga 99 
                 +l++f ++++ + +++alp ++a+dl+ ++++i ++ t   ++  v+s+++Grlsd fGr++vll++ +++a++ ll+++ a++ ++l+++r+++Gl++
  EEA23055.1  30 SLVLFTAFIDQNGVSVALP-IIASDLN-AEDTIPWAGTSSLIANTVFSVLYGRLSDIFGRKSVLLTACVILAVAdLLCGF-AQNAPMLYFFRAMAGLAG 125
                 7899***************.9******.**********************************************666666.68888************* PP

       MFS_1 100 galfpagaaliadwfpkeergraigllsagfslGailgpllgglla.sslgWravfyilaivsllafvlfllllpeepperkrkspkeee......... 188
                 g+++ +++++++d+++ eerg++ g+++a+ +++ i+gp +++ ++ + +gWr+ f+ l+++ + ++ + +++lp ++++ +  +++++          
  EEA23055.1 126 GGITNLAMIFVSDVVTLEERGKYQGIIGACLGVANIVGPFIAAGFIqAPVGWRGFFWTLTPIVACGGAVCWFVLPKSKVTGGLREKIRKIdvwgcltss 224
                 **********************************************9*******************886555555555555555555555********* PP

       MFS_1 189 ..........................................kgtgpaplvpawkallkdpvlwillialllfffgfsglltllplylqevlglsglll 245
                                                            ++++ p+ p  ++++++ v+  ll+ ++l +++++++l++lp y q  +g+s  ++
  EEA23055.1 225 agivlllipisggglyfqwdsamvismlvfgscalvafviieWKVARIPMMP-MSIFRNQSVVA-LLVQSFLLGWVYQSYLYYLPQYYQNIRGYS--VI 319
                 ***********************************99999988888888888.99999999886.8888888888********************..44 PP

       MFS_1 246 aglllallalvgail.allagrlsdrlgrrrrlllallllllaalglallavt.ssavllllvlvliGfglgfvfpsllalasdlappeeagtasglfn 342
                 ++++l+++ ++++ + ++++g ++ r  +   +l++++   ++ +gl +l    +++ +++++l+liG+g+gfvf + l++++ + p+++++ +++  n
  EEA23055.1 320 VSAALSIPLVFMQSVgSVVSGVYISRRHHYGVILWSGFTSWTIGCGLSILFDQdTNPGVCVVALLLIGIGVGFVFQPTLVALQAHSPKSQRAVIISSRN 418
                 44446666666666669999999988666555555555555555555555554588888999************************************* PP

       MFS_1 343 tagslggalg 352
                 +++++gga g
  EEA23055.1 419 FFRCAGGACG 428
                 ******9865 PP

>> TRI12  Fungal trichothecene efflux pump (TRI12)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.7  24.2   3.2e-17   9.5e-14      41     478 ..      21     445 ..       9     491 .. 0.76

  Alignments for each domain:
  == domain 1  score: 50.7 bits;  conditional E-value: 3.2e-17
       TRI12  41 rvvasfaafslnvvatyfvlqasas.alpnilqdvgqsensslfstlwttgqavsilvmgrltdrfgrrpfvilthilglvgaivgctatkfntllaam 138
                 r++  ++++sl  + t f+ q   s alp i  d+   +      t   + ++v  ++ grl+d fgr+ +++ + ++  v  ++   a++   l    
  EEA23055.1  21 RLLIVISCISLV-LFTAFIDQNGVSvALPIIASDLNAEDTIPWAGTSSLIANTVFSVLYGRLSDIFGRKSVLLTACVILAVADLLCGFAQNAPMLYFFR 118
                 666666777775.45666666655439*********9999999999999*****99*************998888888888888888888899999999 PP

       TRI12 139 tllgvaagpaga.splfvgelms..nktkflgllivsipvvvtsglspylgqrlaiqgswrwifyiyiitsaiavllivvwyyppsfaqlhgkkvrkre 234
                 ++ g+a g     + +fv ++++  ++ k+ g++   +   v + ++p++   + iq    w  + + +t  +a    v w+  p  +   g     re
  EEA23055.1 119 AMAGLAGGGITNlAMIFVSDVVTleERGKYQGIIGACL--GVANIVGPFIAAGF-IQAPVGWRGFFWTLTPIVACGGAVCWFVLPKSKVTGG----LRE 210
                 9****99876542789***9875227889999765555..5566689**98765.89988888888999**************998776555....589 PP

       TRI12 235 elakldwigiilvivgvslfllgvswggkpnspwnsakviglissglgslvvfalyevygkpvrpivppalfkdtrgfvcillissimgamnlslviiy 333
                 ++ k+d  g +  ++g+ l+l+ +s gg     w+sa vi ++  g  +lv f + e +     p++p ++f++ + +v++l+ s ++g +  s     
  EEA23055.1 211 KIRKIDVWGCLTSSAGIVLLLIPISGGGL-YFQWDSAMVISMLVFGSCALVAFVIIE-WKVARIPMMPMSIFRN-QSVVALLVQSFLLGWVYQSYLYYL 306
                 999**********************8886.568**********************99.566788********97.578999****************** PP

       TRI12 334 pqqvvnifgsslknweetawmsatasfgtgagvvvlgslfhlvrhirwqilvgalwltaflgamssv.nrdnkna..aialsvlsgfvvawaqditmll 429
                 pq   ni g s+     +a +s    f    g vv g      rh    il   +  +  +g+  s+   ++ n   ++   +l g+ v++  + t++ 
  EEA23055.1 307 PQYYQNIRGYSVI---VSAALSIPLVFMQSVGSVVSGVY-ISRRHHYGVILWSGF-TSWTIGCGLSIlFDQDTNPgvCVVALLLIGIGVGFVFQPTLVA 400
                 *********9986...46778888899999998887754.444554444444333.2333333333312223333112333356788888888888777 PP

       TRI12 430 vqfittdedlgvafavvaaarpfagsiftaafislysnrypkelashls 478
                 +q  +   +     av+ ++r f+     a+ +++ +      l shl 
  EEA23055.1 401 LQAHSPKSQR----AVIISSRNFFRCAGGACGLAISATILQSGLRSHLP 445
                 7766655543....45556666666665555555555555555555555 PP

>> Sugar_tr  Sugar (and other) transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   42.8   6.7   1.1e-14   3.1e-11      56     195 ..      68     203 ..      51     214 .. 0.91
   2 ?    2.5   7.1     0.018        53      43     157 ..     285     431 ..     229     455 .. 0.68

  Alignments for each domain:
  == domain 1  score: 42.8 bits;  conditional E-value: 1.1e-14
                 HHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHH-TTTTSS-TGGGGGHHHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHH CS
    Sugar_tr  56 lvGaiiGslfagllgdrfGRkkslliaavlfvigavlqaaakgknsvevlivgRvlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilva 154
                 l+  ++ s++ g l+d+fGRk++ll+a+v++ ++ +l+++a+   +  +l++ R  +G++ G++++l+ +++s + + + Rg+  ++   ++ +  +v+
  EEA23055.1  68 LIANTVFSVLYGRLSDIFGRKSVLLTACVILAVADLLCGFAQ---NAPMLYFFRAMAGLAGGGITNLAMIFVSDVVTLEERGKYQGIIGACLGVANIVG 163
                 56667778999*******************************...99**************************************************** PP

                 HHHHHHHHTSS-TTHHHHHHH.CCHHHHHHHHHHGGGS---H CS
    Sugar_tr 155 aifglglnktsnadgwrillg.lqlvpallllilllflPESP 195
                  ++ +g+ +     gwr +++ l+ + a   ++++++lP S+
  EEA23055.1 164 PFIAAGFIQAPV--GWRGFFWtLTPIVACGGAVCWFVLPKSK 203
                 ******988777..9**9998467788888999999999885 PP

  == domain 2  score: 2.5 bits;  conditional E-value: 0.018
                 H..................................HHHHHHHTHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHH.HHHHHHHH-TTTTSS-TGGGGGH CS
    Sugar_tr  43 e...............................ssvlsglivsiflvGaiiGslfagllgdrfGRkkslliaavlf.vigavlqaaakgknsvevlivgR 109
                                                 s + s ++   +++ + +Gs+++g  + r     ++l +++ +  ig  l+++ +++++  v +v+ 
  EEA23055.1 285 VvallvqsfllgwvyqsylyylpqyyqnirgySVIVSAALSIPLVFMQSVGSVVSGVYISRRHHYGVILWSGFTSwTIGCGLSILFDQDTNPGVCVVAL 383
                 055555555555555555555555555555534444444444466788999999998877777777777766655279999999999999********* PP

                 HHHHHHHHHHHHHHHHHHHTTS-SCCHHHHHHHHHHHHHHHHHHHHHH CS
    Sugar_tr 110 vlvGigvGlasvlvPmyisEiApkklRgalvslyqlaitfGilvaaif 157
                 +l+GigvG++   + + ++  +pk+ R  ++s  +++  +G   +  +
  EEA23055.1 384 LLIGIGVGFVFQPTLVALQAHSPKSQRAVIISSRNFFRCAGGACGLAI 431
                 ********9988888888888899999999999888888887666555 PP

>> MFS_1_like  MFS_1 like family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   3.2   4.9e-06     0.015     275     371 ..      73     168 ..      57     181 .. 0.89
   2 !   11.7  12.8   2.8e-05     0.084     187     372 ..     244     434 ..     218     443 .. 0.74

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 4.9e-06
  MFS_1_like 275 plfffaeklleklGhvklliiallayilrfllyaiienawlvlpievLhgisfgllwaaaveyvskiapksleatgqgllsglyfglGralGsliGG 371
                 ++ ++  +l +++G   +l++a ++ ++  ll ++ +na ++ ++ ++ g++ g +   a+ +vs++++ + ++++qg++ + + g+ + +G +i+ 
  EEA23055.1  73 VFSVLYGRLSDIFGRKSVLLTACVILAVADLLCGFAQNAPMLYFFRAMAGLAGGGITNLAMIFVSDVVTLEERGKYQGIIGA-CLGVANIVGPFIAA 168
                 566777899**********************************************************************965.5999999**98863 PP

  == domain 2  score: 11.7 bits;  conditional E-value: 2.8e-05
  MFS_1_like 187 aallvisllvvlilnetek.esklkvtkslqvllnilknpeviifllvalilgmswgiienFlflYL.kelgasntllGsl.valgvvaeiplfffaek 282
                 ++ +vis+lv+ ++        + kv+ ++   + i++n++v+++l+  ++lg ++  +  +l  Y+ +  g+s ++  +l ++l  + ++   + + +
  EEA23055.1 244 DSAMVISMLVFGSCALVAFvIIEWKVARIPMMPMSIFRNQSVVALLVQSFLLGWVYQSYLYYLPQYYqNIRGYSVIVSAALsIPLVFMQSVGSVVSGVY 342
                 5566666666666665553135667788888899*********************************55568888776665144444555555555555 PP

  MFS_1_like 283 lleklGhvklliiallayilrfllyaii....enawlvlpievLhgisfgllwaaaveyvskiapksleatgqgllsglyfglGralGsliGGl 372
                 + ++    ++l  ++++ +   ++++i+    +n+ +++++ +L gi +g ++       + + pks +a +++    ++ ++G+a G  i+  
  EEA23055.1 343 ISRRHHYGVILWSGFTSWT-IGCGLSILfdqdTNPGVCVVALLLIGIGVGFVFQPTLVALQAHSPKSQRAVIISS-RNFFRCAGGACGLAISAT 434
                 5555555555555555555.557777777*999*********************9999999**********9985.556689999999888844 PP

>> PQ-loop  PQ loop repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   0.1         5   1.5e+04      44      55 ..     126     137 ..     123     138 .. 0.76
   2 ?   -0.5   0.1      0.36   1.1e+03      24      40 ..     279     295 ..     277     299 .. 0.81
   3 !   16.0   0.5   2.5e-06    0.0074      16      53 ..     304     344 ..     301     348 .. 0.90

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 5
     PQ-loop  44 Gdilsllyliln 55 
                 G+i++l+ ++++
  EEA23055.1 126 GGITNLAMIFVS 137
                 889998888765 PP

  == domain 2  score: -0.5 bits;  conditional E-value: 0.36
     PQ-loop  24 NykrkSteGlSilflll 40 
                 +++++S++ l + ++ll
  EEA23055.1 279 IFRNQSVVALLVQSFLL 295
                 899***99998877776 PP

  == domain 3  score: 16.0 bits;  conditional E-value: 2.5e-06
     PQ-loop  16 syiPQiikNykrkSt...eGlSilflllwllGdilsllyli 53 
                  y+PQ+++N +  S+     lSi  ++++ +G++ s +y+ 
  EEA23055.1 304 YYLPQYYQNIRGYSVivsAALSIPLVFMQSVGSVVSGVYIS 344
                 69************976679******************985 PP

>> DUF1129  Protein of unknown function (DUF1129)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.5      0.97   2.9e+03      85     136 ..      67     118 ..      65     171 .. 0.69
   2 ?    2.3   1.3     0.033        97     111     140 ..     283     312 ..     244     343 .. 0.75
   3 ?   10.6   0.0   9.6e-05      0.29      96     149 ..     364     416 ..     357     456 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 0.97
     DUF1129  85 sLlllalfallfg.ilalfskkkqtasiGlitlllvalvgGlamvlvyrlltr 136
                 sL+   +f++l+g +  +f++k+   +   + l++  l+ G+a    + ++ r
  EEA23055.1  67 SLIANTVFSVLYGrLSDIFGRKSVLLT-ACVILAVADLLCGFAQNAPMLYFFR 118
                 667777777777733445665444443.6666666666677665555555544 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.033
     DUF1129 111 iGlitlllvalvgGlamvlvyrlltrekkk 140
                  ++++ll+ +++ G+++  + ++l ++ ++
  EEA23055.1 283 QSVVALLVQSFLLGWVYQSYLYYLPQYYQN 312
                 4689****************9999775333 PP

  == domain 3  score: 10.6 bits;  conditional E-value: 9.6e-05
     DUF1129  96 fgilalfskkkqtasiGlitlllvalvgGlamvlvyrlltrekkkkkrpplwkr 149
                  g+  lf+++++     +++lll+++ +G+++  +   l+ + +k++r  ++ +
  EEA23055.1 364 CGLSILFDQDTNPGV-CVVALLLIGIGVGFVFQPTLVALQAHSPKSQRAVIISS 416
                 588999999777775.********************************988754 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (574 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       654  (0.0364772); expected 358.6 (0.02)
Passed bias filter:                      279  (0.0155614); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.58u 0.33s 00:00:00.90 Elapsed: 00:00:00.46
# Mc/sec: 3748.20
//
Query:       EEA23056.1  [L=582]
Description: allantoin permease, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.4e-89  299.3  41.7    5.5e-89  298.9  41.7    1.0  1  Transp_cyt_pur  Permease for cytosine/purines, uracil, thiami


Domain annotation for each model (and alignments):
>> Transp_cyt_pur  Permease for cytosine/purines, uracil, thiamine, allantoin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  298.9  41.7   3.1e-93   5.5e-89       1     438 [.      47     500 ..      47     505 .. 0.97

  Alignments for each domain:
  == domain 1  score: 298.9 bits;  conditional E-value: 3.1e-93
  Transp_cyt_pur   1 pvpeeeRtwktlnlfsiWlganlnintwvigalglalgLnwwqsvlviivgnligaifvallglaGakyGlpfpilsRasfGirgsllplllrvv 95 
                     p p ++Rtw++l +f+ +l + ++ + + +g+++++ gL ww  +++ ++g++++ i+v+l+++   ky++ fp+  Ras Gi g+ l +++r+ 
      EEA23056.1  47 PTPPSQRTWTALHFFAYYLTTTFSPSSYNLGSSLVSKGLQWWHGMIAAVIGSIFLSIIVILNSRGAVKYHVGFPVYTRASSGIGGAKLFIFVRAS 141
                     6799******************************************************************************************* PP

  Transp_cyt_pur  96 iaivwfgvqawiGsealllmlgkifgk.wleigg...ailgtsltelvtffifwvvslvivllgvskirkffviaallvpvaafgfliwalvkae 186
                     +a ++f+vq + G++  ++ l+ ++g+ w+ i++   a  g++   l++ffifw+v++++++l ++ +r++fv++a+ + va fg+  wa+ + +
      EEA23056.1 142 VATIYFAVQSYYGGQLTSVCLRAMIGSkWDSIPNhlpADAGITSKNLLAFFIFWIVQFPVMFLHPTILRHLFVFKAVYTTVALFGVMGWAIHENG 236
                     **********************************999999******************************************************* PP

  Transp_cyt_pur 187 g..Gpvldkavklgkse...lflsavagvlagfatlilnapDFtryaktkkssvkiqlvavpllftlllligilvaaaakaayganawspldila 276
                     g  G+   ++ +l+ s+    ++sa+++v+++  ++ +n pD +ryak++ + +++q v++ l  +l+++++ + ++a++a+ g+++w++ d+ +
      EEA23056.1 237 GsiGSFSFQKNSLHGSAlvwPMISAINSVMGALCPILINQPDVARYAKRYSQVTWSQSVGILLSKVLVMFVSCATTSATTAILGKTYWNVWDLYN 331
                     *99999999999997778999*************************************************************************9 PP

  Transp_cyt_pur 277 kfdet.......agvllililvalaqlgvnisanllsagldlaallPkkinikrgsliaavialvivpwkllssssklftaflsllavflspvag 364
                      ++         ag++++++ + la +++n+  n+l+ g d + l+P+++ni rg +i+a++a ++vpwk ++s+s+ f++fl+ ++vfl p+ +
      EEA23056.1 332 AILTEywspaarAGIFFASLGMILAIIATNAGTNSLPVGADSSGLFPRYLNIVRGQVICALLAPLFVPWKIIASASS-FLTFLGSYTVFLMPICA 425
                     999999999********************************************************************.***************** PP

  Transp_cyt_pur 365 viiadyfvvrrgylklaalytrrrgsaYwyrkgvNwravaayivGiaaglvgvagsvg.ikvvkgaeklfdlsyl 438
                     ++++dy+++r+g+ ++  lyt+ +g +Y y+ g+N+ra++a+++G++  + gvags    +v +  ++++ l+++
      EEA23056.1 426 IMVVDYWIIRKGNFHIPSLYTKAPGTPYAYWHGWNLRALVAWVCGVVFVVHGVAGSLNpGSVNAASTRMYSLGFF 500
                     *******************************************************99977777777778877776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (582 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       655  (0.036533); expected 358.6 (0.02)
Passed bias filter:                      295  (0.0164538); expected 358.6 (0.02)
Passed Vit filter:                        29  (0.00161749); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.56u 0.29s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 3966.71
//
Query:       EEA23057.1  [L=700]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.2e-24   85.4   7.4      5e-24   84.8   7.4    1.3  1  Fungal_trans  Fungal specific transcription factor domain
    1.9e-07   31.1   8.8    3.6e-07   30.2   8.8    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
  ------ inclusion threshold ------
      0.041   14.0   1.4      0.081   13.0   0.1    2.1  2  P5-ATPase     P5-type ATPase cation transporter


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   84.8   7.4   8.4e-28     5e-24       1     266 [.     221     471 ..     221     472 .. 0.88

  Alignments for each domain:
  == domain 1  score: 84.8 bits;  conditional E-value: 8.4e-28
  Fungal_trans   1 ldrffsnfhpqfpilhk...psflpkt....ssenssksayaspllllailalGalfsesetkesnssltsesqefiafplraeilihedfsspsss 90 
                   ++ +f+ +   +p+++    ++++++      s+n s   +  ++ l++++a+G++++  ++k   ss++ses       l   +l+h ++  +s+s
    EEA23057.1 221 ISAYFTRVATRYPFMDWeemEKLHSDRlrlsTSNNLSRREKFGTFKLYLVYAIGSSLLALTEKDFASSSSSES-------LYMTALQHISAARESRS 310
                   57788888888888888554444444488766777777777778889******************99999988.......57777888899999999 PP

  Fungal_trans  91 lwilqsLlllelyektssd.ralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrppllddsqinlpLP 186
                   ++ +++  ll +y++ ss    + ++++g+a+r + +lgLhr+ +  +      ++  ++++ r l+w++++l++ti++ lGrp+ + d  i+++LP
    EEA23057.1 311 IHNIEAMTLLVIYHLRSSAsSHGLWYMIGLAMRTCIDLGLHRKNKEIN------RDSITSQRYRALFWTVYSLERTISISLGRPVSIADRHIDVELP 401
                   *****************95599***********************999......77777**************************99********** PP

  Fungal_trans 187 cddddlwesddaseetlvetklsneeksrkiasfllaLkkilskiagsllsiekqlqqrdlqseklswveeleraldnWr 266
                   +      +  + ++++ ++    ++++s  +a  l+++  + s +++s++   k+l++  +       ++++++++++W+
    EEA23057.1 402 DVIGSTAMNRNPETSFVKN----SKSQSNAMAIHLFRIHILESRMHHSIYRTDKPLSELCQK------LTRHYHEFEAWK 471
                   9999666666666666666....78*************************************......***********7 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.2   8.8     6e-11   3.6e-07       1      31 [.      27      57 ..      27      63 .. 0.94

  Alignments for each domain:
  == domain 1  score: 30.2 bits;  conditional E-value: 6e-11
                SS-HHHHHCT---STSSSS-HHHHHCTHHHC CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCt 31
                +aC++C+ kK +Cd++ P+C+nC+k+ +eC 
  EEA23057.1 27 TACTRCKDKKQRCDGNYPVCGNCQKVVAECD 57
                69****************************7 PP

>> P5-ATPase  P5-type ATPase cation transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.8   0.1      0.52   3.1e+03      52      96 ..      53      99 ..      46     119 .. 0.48
   2 ?   13.0   0.1   1.4e-05     0.081      17      76 ..     537     608 ..     530     655 .. 0.60

  Alignments for each domain:
  == domain 1  score: -1.8 bits;  conditional E-value: 0.52
   P5-ATPase 52 Lkeadvvlie..defgelsvkkvrkleyerp..lstvfsseqeegeeke 96
                ++e+d  +i+  d+  e ++k ++    e +  l ++ +++++  +++e
  EEA23057.1 53 VAECDLHVIRadDRLVEEYIKALEDRVAELEirLDSSSTTTTT--TTTE 99
                6788888998875555555555444432222113333322222..2222 PP

  == domain 2  score: 13.0 bits;  conditional E-value: 1.4e-05
   P5-ATPase  17 lalyilgciltlGlllLlfrWlPewrvkltgkpcpLkeadvvlie............defgelsvkkvrkle 76 
                 + ++ +  ++  G+ lL + W     v+ + ++  +++++ vl              d f+ l+ + ++kl+
  EEA23057.1 537 HSFIAVQTVFVAGVTLLFCVWTKTSTVWSVKVSNGIRACSNVLFVmgertmwvkkyrDAFELLTNATMEKLQ 608
                 55677788999********************************99644433333333333333333333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (700 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       862  (0.0480785); expected 358.6 (0.02)
Passed bias filter:                      511  (0.0285013); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.65u 0.27s 00:00:00.92 Elapsed: 00:00:00.43
# Mc/sec: 4924.17
//
Query:       EEA23058.1  [L=596]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    3.7e-12   46.2   0.0    9.1e-11   41.7   0.0    2.5  2  DDE_1         DDE superfamily endonuclease
    1.1e-08   35.0   0.3      3e-08   33.6   0.3    1.8  1  HTH_Tnp_Tc5   Tc5 transposase DNA-binding domain
  ------ inclusion threshold ------
      0.024   14.8   0.1        0.5   10.5   0.0    2.7  3  Pcc1          Transcription factor Pcc1
      0.052   12.5   1.6      0.078   11.9   1.6    1.2  1  Amidase       Amidase


Domain annotation for each model (and alignments):
>> DDE_1  DDE superfamily endonuclease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.1     0.016        70       2      29 ..     193     220 ..     192     248 .. 0.77
   2 !   41.7   0.0     2e-14   9.1e-11      59     175 .]     223     343 ..     219     343 .. 0.85

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.016
       DDE_1   2 erltvllcanaagsekLkplvigkaksp 29 
                 +++ ++++++ a++  + p +i+ aks 
  EEA23058.1 193 REWITTIGCICANGTAISPALIYMAKSG 220
                 678999****************988764 PP

  == domain 2  score: 41.7 bits;  conditional E-value: 2e-14
       DDE_1  59 feeWLkvfdkrle.......aekrkilLlldssrshetvel.leselqniklvflPassasllqPldqgvvselKarYrrqllqalleeqnrlskeqkk 149
                    WL+ fd   +        +   +l  ld+++sh t+ + + ++++ i l+++Pa+s+++lqP d+ ++s+l + Y +ql + +++  +        
  EEA23058.1 223 QDSWLQDFDAEQHrcffatsDKPGMALAYLDGHGSHVTMRFiEYCDKNRILLAIFPAHSTHTLQPPDVAIFSPLSTAYTEQL-RRFINDCQGFTR---- 316
                 56788888887777888765555567788************999**********************************8765.556666655555.... PP

       DDE_1 150 ltlldalkfikkAwn.avsketiksaf 175
                 lt +d+++   ++w+  +++e+i saf
  EEA23058.1 317 LTKRDFFRLFWASWEaTFTSENILSAF 343
                 9**************99******9987 PP

>> HTH_Tnp_Tc5  Tc5 transposase DNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   33.6   0.3   6.6e-12     3e-08       2      60 ..      59     108 ..      58     115 .. 0.91

  Alignments for each domain:
  == domain 1  score: 33.6 bits;  conditional E-value: 6.6e-12
                  HHHHHHHHHHHHHHC-CT---SCHHHHHHHHHHHHHSSSCT-TT-S--CHHHHHHHHHT CS
  HTH_Tnp_Tc5   2 pelEkaLleWirqlrergipitgelirekAqelaslaadlgepdfkaSkgWldrFkkRh 60 
                  +e+ + L++Wi+ql+erg p+t++++ + A+e+         + + ++k+W  r++k h
   EEA23058.1  59 KEQSRTLIKWINQLTERGLPPTNSMLENFAREI---------SGKEPGKNWASRWLKAH 108
                  68999****************************.........67889**********99 PP

>> Pcc1  Transcription factor Pcc1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.5   0.0   0.00011       0.5      12      50 ..       5      43 ..       1      59 [. 0.88
   2 ?    0.8   0.0      0.12   5.5e+02      49      66 ..     380     397 ..     377     398 .. 0.91
   3 ?   -2.7   0.1       1.5   6.8e+03      12      36 ..     531     558 ..     528     583 .. 0.57

  Alignments for each domain:
  == domain 1  score: 10.5 bits;  conditional E-value: 0.00011
                HHHHHHHHHHHHHCHC-TTECEEEEEEETTEEEEEEEES CS
        Pcc1 12 rlAsialrtLqvDkelsplavkrslslegnvLqveykAt 50
                +lA  alr+L++D++++ + v r++ ++++ L  +++  
  EEA23058.1  5 ELALEALRSLKPDEKPNISLVARTYGVNQSNLSKRFRGV 43
                78888********9999888***********99998875 PP

  == domain 2  score: 0.8 bits;  conditional E-value: 0.12
                 ESSHHHHHHHHHHHHHHH CS
        Pcc1  49 AttnrmLRvavngflesl 66 
                 A++ r LR  v+g++e+l
  EEA23058.1 380 AEDWRRLRKLVQGVFEDL 397
                 9999************98 PP

  == domain 3  score: -2.7 bits;  conditional E-value: 1.5
                 HHHHHHHHHHHHH..CHC-TTE.CEEEE CS
        Pcc1  12 rlAsialrtLqvD..kelspla.vkrsl 36 
                 +lA+ a   Lq D  + +s ++  k+++
  EEA23058.1 531 ELAKLAHLQLQNDvlATPSAPKrAKKQV 558
                 6777777778877553333333333333 PP

>> Amidase  Amidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   1.6   1.7e-05     0.078     309     396 ..     473     564 ..     445     587 .. 0.69

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 1.7e-05
                 ---SS-SCCCCCCCHHHHCCS-HHHHHHHHHHHHHCSCCCCCCCHHHHHHHHH.HHHHHHHHHCCC...BSEEEEESSSSS--BCCCCCHHH CS
     Amidase 309 erlsetkvlsellpksraellgeevkrrielgnyalsaeasskyylkaqkvrr.llrrefakafee...lDvllsPtaptpaprlgekdkti 396
                 +  + ++  +++  k+ +++l+++ k + +    ++ +e++++ +++a++ +r   ++e+ak+ +     Dvl++P+ap+ a+++  k+ ++
  EEA23058.1 473 KDEQAAQEQARKDDKKLQQELTKQAKEQEKAERAQIRQEKQEQRLQEATEKQRlKDEQELAKLAHLqlqNDVLATPSAPKRAKKQVSKQVKV 564
                 2333344445666667777777777777777777777777777777777666656667777765557778*************998887655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (596 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      3022  (0.168554); expected 358.6 (0.02)
Passed bias filter:                      842  (0.046963); expected 358.6 (0.02)
Passed Vit filter:                       165  (0.00920297); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.85u 0.33s 00:00:01.18 Elapsed: 00:00:00.46
# Mc/sec: 3871.43
//
Query:       EEA23059.1  [L=337]
Description: chitin deacetylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.2e-08   34.9   0.0      2e-08   34.2   0.0    1.3  1  Polysacc_deac_1  Polysaccharide deacetylase
  ------ inclusion threshold ------
      0.014   15.0   0.1       0.09   12.4   0.1    2.2  2  DUF3146          Protein of unknown function (DUF3146)


Domain annotation for each model (and alignments):
>> Polysacc_deac_1  Polysaccharide deacetylase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.2   0.0   2.2e-12     2e-08      13     100 ..      81     168 ..      77     192 .. 0.91

  Alignments for each domain:
  == domain 1  score: 34.2 bits;  conditional E-value: 2.2e-12
                      EEESSCSCHHHHHHHHHHCT--EEEEE-HHHHCH-HHHHHHHHHTTEEEEE--SS--EGGGSHHHHHHHHHHHHHHHHHHHHS----E CS
  Polysacc_deac_1  13 fDdgprdntteilpvLkkykvkatffvigglvedypdevremaasGveignHtinhsnlkrlseeevrreierakdalrkalgreprl 100
                      f+ g+r+   +++ ++k+ +++ t f +    +++p  +++++++G+ei++H++ + + ++   ee ++ i+++   l+++ g+ p+ 
       EEA23059.1  81 FEYGSRSASWRLIRLFKEFGWNFTTFAVALALKKNPTFAKALVRDGHEIAAHGYRWLDVWDYNLEEDKEYIKKTLLLLKEVSGEIPVG 168
                      89999**********************************************************9999999999999999999986655 PP

>> DUF3146  Protein of unknown function (DUF3146)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.1     1e-05      0.09      27      73 ..      98     150 ..      95     154 .. 0.83
   2 ?   -1.2   0.0      0.18   1.6e+03      32      61 ..     229     257 ..     214     270 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 1e-05
     DUF3146  27 eyeWqfkWafrkgeLsvePslGraLikepLe......rflekkDyqLepGgdY 73 
                 e+ W+f+    +  L+ +P++ +aL+++  e      r+l  +Dy+Le  ++Y
  EEA23059.1  98 EFGWNFTTFAVALALKKNPTFAKALVRDGHEiaahgyRWLDVWDYNLEEDKEY 150
                 78999998888889************99753334445***********99999 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.18
     DUF3146  32 fkWafrkgeLsvePslGraLikepLerfle 61 
                 +++ +++g+ ++ P +G + + e+ e +l+
  EEA23059.1 229 YNYDCNDGKFHMAPGFGSS-VGETYENYLK 257
                 6788899999999999976.4566666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (337 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       423  (0.0235931); expected 358.6 (0.02)
Passed bias filter:                      388  (0.0216409); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.48u 0.27s 00:00:00.75 Elapsed: 00:00:00.44
# Mc/sec: 2308.54
//
Query:       EEA23060.1  [L=518]
Description: amidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      9e-86  288.6   0.2    1.1e-85  288.3   0.2    1.0  1  Amidase   Amidase


Domain annotation for each model (and alignments):
>> Amidase  Amidase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  288.3   0.2   6.3e-90   1.1e-85      36     451 .]      76     502 ..      59     502 .. 0.85

  Alignments for each domain:
  == domain 1  score: 288.3 bits;  conditional E-value: 6.3e-90
                 --TTT......TTTT-EEEEETTB--TTSB--TTSGGGTT-B-SS--HHHHHHHHTT-EEEEEE--SGGG-SSSSTT-TT---BBTTCTCCB--SSSHH CS
     Amidase  36 dkkrargkekgpLhGvPisvKDnidvkgvpttaGskalenypaekDatvverLkkaGavilgkTnmdefamgsstensvfgptrNPwdksrtpGGSSGG 134
                 ++k  ++ +   L G  +++KDni+v+gvp+ +G++++ ++++++Datvv+r+ +aG +i gk++++ +  g+ + + ++gp++NP+ + +++GGSS+G
  EEA23060.1  76 NAKS-TEPKSDLLKGKTVCLKDNIAVAGVPCLLGTDTFQDWIPKTDATVVTRILDAGGIITGKAVCENLSRGAVSATAATGPVHNPYAPGYSAGGSSSG 173
                 3333.4678889*************************************************************************************** PP

                 HHHHHHTTSSSCEEEEESSSTTHHHHHHCTSEEEE--TTSC--TTB--SSTTT-EEEEEESSHHHHHHHHHHHBS--TT-TTS----.......HHHHH CS
     Amidase 135 sAAavAaglvplaiGtDtGGSiRiPAsfcglvGlKPtygrvSragvvalessldvvGplarsvedlalllrvilgedpkdstssvip.......eesed 226
                  AA+vA+g ++++iG D GGSiRiPAs+cgl+G+KPt g+v++ g+ +  + ld vGp++++  d a+ll++i+g d  d++++          + ++ 
  EEA23060.1 174 TAALVASGATDMGIGCDQGGSIRIPASLCGLYGFKPTAGLVPYTGIASNDACLDYVGPMTTTCLDNAILLEAIAGVDGLDDRQTAGApfpkqvpNYAQL 272
                 *****************************************************************************9988877544577776666677 PP

                 HHHCTT---TT-EEEEEGGGC.SS---CCHHHHHHHHHHHHHCTT-EEEEEE-CCGGGHHH.HHHHHHHHHHHHHTTT-SSSSS.---SS-SCCCCC.. CS
     Amidase 227 laeelkkslkglriGvvkedg.vasldpevqravekalkaLeeaGhevvevelpsleeals.lyylilvaeassnlarylgvry.erlsetkvlsel.. 320
                 l+e+++   kgl+iG++ke      ++p v++ +++a    +++G++v++v++p + +a   +++l  +     n +  lg+   +r     +l e+  
  EEA23060.1 273 LEETKEDGIKGLKIGILKEGLdLPGINPRVEAKFQDAMNVFRRLGATVEDVHIPIHSQARTvIVVLSKMG----NHMGMLGKATgRRQMMLTDLFEKkg 367
                 7778888889*********98899********************************99999333334444....4444455554433333333333300 PP

                 ..CCHHHHCCS-HHHHHHHHHHHHHCSCCCCCCCHHHHHHHHHHHHHHHHHHCCCBSEEEEESSSSS--BCCCCCHHHCSHHHHHGCCTTT...HHHHH CS
     Amidase 321 ..lpksraellgeevkrrielgnyalsaeasskyylkaqkvrrllrrefakafeelDvllsPtaptpaprlgekdktidsytvlynlldftavvvpvnl 417
                   ++    ++++   k  ++ g+ya ++   s+ y k  +  r l+++++ka+ e+Dvl++Pt+ t+  +l ++d t      + ++   ++++ p+n 
  EEA23060.1 368 lpYTPEVLSKMSVMSKEGLIAGEYAWKHY--STLYPKVVNLIRKLQDAYDKALGEYDVLVMPTTITESNTLPAADAT--PLEHMDASKGKLENTSPFNA 462
                 00333333444445566677777777765..799****************************************974..567788888888888***** PP

                 TT--EEEEECCCCT.......TECEEEEEEESTT-HHHHH CS
     Amidase 418 aglpalsvpagksed......glPvGvqvigkafqeetlL 451
                  g+pal+vp+g   +       +P ++q++g++++e t+L
  EEA23060.1 463 SGHPALAVPIGLVPSrenptiTMPTSMQIVGRYWDELTIL 502
                 *************8889*******************9886 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (518 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       443  (0.0247086); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.59u 0.30s 00:00:00.88 Elapsed: 00:00:00.48
# Mc/sec: 3266.18
//
Query:       EEA23061.1  [L=646]
Description: alpha-galactosidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    8.2e-51  172.8   0.4    1.7e-50  171.8   0.4    1.6  1  Melibiase_2  Alpha galactosidase A
    4.2e-12   45.9   0.1    1.1e-11   44.6   0.1    1.8  1  Melibiase_C  Alpha galactosidase C-terminal beta sandwich dom


Domain annotation for each model (and alignments):
>> Melibiase_2  Alpha galactosidase A
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  171.8   0.4   1.9e-54   1.7e-50       1     284 []      23     305 ..      23     305 .. 0.86

  Alignments for each domain:
  == domain 1  score: 171.8 bits;  conditional E-value: 1.9e-54
                  S--EEEESHHHHTT---TTTSTTTSSSHHHHHHHHHHHHHTTHHHHT--EEE--SS-B-SS--TTS---B-TTTSTTHHHHHHHHHHHTT-EEEEEEE CS
  Melibiase_2   1 tppmgwlawerfrcnvdceedpenciseklfmeladvlaedgykdlgyeyviiddcwlakerdkegrlqadpkrfpsgikkladyvhskglklgiyad 98 
                  tp mgw++++ + c       p+    e ++ + a+ l++ g   lgy yv+ d  w+  +r  +g l+ d++rfpsg  +l++y+h  gl +g+y+d
   EEA23061.1  23 TPQMGWNTYNHYGCS------PN----EAIVHSNAQALVDLGLASLGYRYVTTDCGWTVADRLPNGSLTWDSTRFPSGFPALGQYLHGLGLLFGVYQD 110
                  799999999999885......44....66678899*************************************************************** PP

                  SSSB-TTSSB...--TTTHHHHHHHHHHHT--EEEEE-TSSSHHHH............HHHHHHHHHHHHHTTS--EEE.E-HHHHH.TTTS---HHH CS
  Melibiase_2  99 lgtktcagyp...gslkyleidaktfadwgvdllkldgcysnleel............aegykelslalnktgrsivys.cewplyavvkkkkvdyte 180
                   g   c+  p   gsl++  +da+tfa+wgvd lk+d cys+  +             +  y ++s al +  r+i++  cew + + +       + 
   EEA23061.1 111 AGILLCGSPPnqiGSLYHELQDAQTFASWGVDSLKYDNCYSDAATNypnvnyapstspEPRYANMSNALSQQDRAILFQvCEWGVDFPA-------AW 201
                  *******99855467777779*******************87654311111111111134699*************9955***998722.......22 PP

                  HHHH-SEEE-SS---SSHHHHHHHHHHHHHTHHHHTTT-BTTBEEE---B-TTSSSS-HHHHHHHHHHHHHTT--EEE-S-TTS....--HHHHHHHT CS
  Melibiase_2 181 iaktcnlwrnyddiqdswdsvkeivdyfaenqdvlvevagpgkwndpdmliignfglsldqqraqmalwailaapllmsndlrk....ispeakalll 274
                    +  n wr  +di+ sw+s+  +v+ +a +     + agpg+w d dml +gn   s+ ++++ ++lwail +pl++ + l++    i++e+ a+l+
   EEA23061.1 202 APSLGNSWRIGNDISSSWTSIYRLVNQIAPQT----DFAGPGQWPDLDMLEVGNNVYSTAEEQTHFSLWAILKSPLVIGAALKDaatsINEESLAILK 295
                  346789********************999875....57*****************************************999853333889999**** PP

                  -HHHHHHHT- CS
  Melibiase_2 275 nkeviainqd 284
                  +k+vi+ nqd
   EEA23061.1 296 QKDVISYNQD 305
                  *********9 PP

>> Melibiase_C  Alpha galactosidase C-terminal beta sandwich domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.6   0.1   1.3e-15   1.1e-11       1      71 []     319     393 ..     319     393 .. 0.85

  Alignments for each domain:
  == domain 1  score: 44.6 bits;  conditional E-value: 1.3e-15
                  ETTEEEEEEE-SSS-EEEEEEE....-E..EEEE-GTT--S-..EEEEETTTTEEE-..TT--EEEE-TT-EEEEEE CS
  Melibiase_C   1 egdlqvWakpLsdGdvaValfN....rttvtvdwsdlglpgsssysvrDlWtgkdlg..tgsssaevpphgvvllrl 71 
                  e++++vW++pLs+ +++ al+N    +  +t+ + d+g++ +    v+D+W++ ++   ++s++aev++hg++ll l
   EEA23061.1 319 EDEYDVWSGPLSGKRIVAALVNwadeKRYLTIALPDIGIQYA--GMVKDIWKNVTIQdvKTSYTAEVEAHGTMLLEL 393
                  5899*******************8642236999989******..9**********55535557**********9976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (646 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       705  (0.0393218); expected 358.6 (0.02)
Passed bias filter:                      417  (0.0232584); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.63u 0.28s 00:00:00.91 Elapsed: 00:00:00.47
# Mc/sec: 4126.04
//
Query:       EEA23062.1  [L=573]
Description: extracellular rhamnogalacturonase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-25   90.1   5.3      2e-25   89.6   5.3    1.1  1  Glyco_hydro_28   Glycosyl hydrolases family 28
    0.00017   21.5   8.6     0.0009   19.1   5.2    3.0  2  Pectate_lyase_3  Pectate lyase superfamily protein


Domain annotation for each model (and alignments):
>> Glyco_hydro_28  Glycosyl hydrolases family 28
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   89.6   5.3   2.2e-29     2e-25      86     319 ..     141     373 ..     107     379 .. 0.90

  Alignments for each domain:
  == domain 1  score: 89.6 bits;  conditional E-value: 2.2e-29
  Glyco_hydro_28  86 kegkkkpkflvikkvknskiknlniknspvfhfsvesgkdltisditidasagdhNtDgidvgsskgvtisntnikngDDciainsgsknisitn 180
                     +++ ++ ++++++kv++++++++ + +sp fh+++   +d  + ++ i   + +   Dgidv  s ++ +++  ++n D c+ ++s s+ni ++ 
      EEA23062.1 141 DKKSTTTRLVRLQKVDSFSVHDIILVDSPAFHLVLDTVQDGEVYNVAIRGGN-EGGLDGIDVTGS-NIWVHDVEVTNKDECVTVKSPSSNILVES 233
                     45668899****************************************8654.4689*****876.8**************************** PP

  Glyco_hydro_28 181 vtcggGHGlSiGSvggrsdntVknvtvkdskvknsenGvRIKtikgatgtvsnvkyeniklknvaypividqdYenkeptgkptsgvkisdvtfk 275
                     v+c+   G  +GS+g     +++++t ++     s+    IK++ g +gtv n+   n   ++ ay + id+ + + +++  +  gv  s++t++
      EEA23062.1 234 VYCNWSGGCAMGSLGAD--TNISDITYRNIYTWSSNQMYMIKSN-GGSGTVQNILLANFIGHGNAYSLDIDTSWAQMSKASGD--GVGYSNITIT 323
                     ***************98..88*********************96.779**************************998877776..9********* PP

  Glyco_hydro_28 276 nvtgtvks...aeavkllcekgskcsdvtmsdvkitg..g.kstskcknv 319
                     n +gt ++      +k+lc +g++c d+t+++ ++    g ++t +c n+
      EEA23062.1 324 NWKGTESNglqRGPIKVLCPAGNPCYDLTIENFAMWTesGdSQTYTCDNA 373
                     *****988654457*******************99654356788899997 PP

>> Pectate_lyase_3  Pectate lyase superfamily protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.1   5.2     1e-07    0.0009       2     205 ..      40     261 ..      39     295 .. 0.54
   2 ?   -0.6   1.1      0.11   9.9e+02     117     152 ..     313     355 ..     263     404 .. 0.50

  Alignments for each domain:
  == domain 1  score: 19.1 bits;  conditional E-value: 1e-07
                      EEGGGGT---EEEEE-HHHHHHHH......HTSS-EEE-SEEEEESS-EEE-SSE..EEEES-.........TTTEEEEE-TT-.....SS--S CS
  Pectate_lyase_3   2 rnVkdyGakgDGvtDdtaaiqkaiscasatttgavVYfPaGtYlvsspiilksgv..qLvGdg.........ngrpvlkaaaaf.....vgagl 79 
                       nV dyGa+ D +tD    + +a    ++   g++VY+P+G Y +s+   l +g+   L+ dg          ++  ++ a++f     + ag 
       EEA23062.1  40 CNVLDYGAVADLSTDLGVPLVSAF---KDCIHGGLVYIPEGRYAMSTWATLDKGTgwALQLDGiiyrngtdgGNMILIEHASDFemfssNSAGA 130
                      59**********************...999*****************99555544332333333344444447777777777774444444444 PP

                      EEES-TTT-..-EEEEEEEEEEEGGGG-SS---S....SEEEES-EEE..EEEEEEEES-SSEEE-SSS---TT---SS--EEEEES-EEES-S CS
  Pectate_lyase_3  80 idgdpyvsggsealiatnnfyrqirnlkiditav....apgatgihwq..taqatslenvefemseasgtkhqgifiengsggflndlvfsglg 167
                      ++g  y  ++ ++  +t   +r +r  k+d+ +v      ++ + h +  t q+ +++nv ++  ++ g   +gi +  gs+  ++d+++++  
       EEA23062.1 131 MQGLGYEFHA-DKKSTT---TRLVRLQKVDSFSVhdiiLVDSPAFHLVldTVQDGEVYNVAIRGGNEGG--LDGIDV-TGSNIWVHDVEVTN-K 216
                      4444444331.222333...3334444444444433343333444533348888888888665555553..344433.23444445555555.5 PP

                      S-SEEES..-EEEEEES-EEE-......S--SEEE-TT-E.EEEEEE CS
  Pectate_lyase_3 168 digiavg..nqqftvrnitfnn......attgievlwgwg.wtlknv 205
                      d  ++v+  + ++ v+++++n             ++++ + +t++n+
       EEA23062.1 217 DECVTVKspSSNILVESVYCNWsggcamG--SLGADTNISdITYRNI 261
                      55555532444555555555443232111..1111112222222222 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.11
                      E.......ES-EEEEEEEEEEES-SSEEE-SSS---TT---SS CS
  Pectate_lyase_3 117 a.......tgihwqtaqatslenvefemseasgtkhqgifien 152
                              t ++w+  +   l++  +++ + +g+ + +++ien
       EEA23062.1 313 DgvgysniTITNWKGTESNGLQRGPIKVLCPAGNPCYDLTIEN 355
                      0222222233344444444455544444444444444454444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (573 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       523  (0.0291706); expected 358.6 (0.02)
Passed bias filter:                      281  (0.0156729); expected 358.6 (0.02)
Passed Vit filter:                        11  (0.000613531); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.27s 00:00:00.84 Elapsed: 00:00:00.44
# Mc/sec: 3878.41
//
Query:       EEA23063.1  [L=546]
Description: c-24(28) sterol reductase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
   1.5e-137  458.9  19.7   1.7e-137  458.7  19.7    1.0  1  ERG4_ERG24  Ergosterol biosynthesis ERG4/ERG24 family


Domain annotation for each model (and alignments):
>> ERG4_ERG24  Ergosterol biosynthesis ERG4/ERG24 family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  458.7  19.7  9.7e-142  1.7e-137       4     431 ..     112     545 ..     109     546 .] 0.96

  Alignments for each domain:
  == domain 1  score: 458.7 bits;  conditional E-value: 9.7e-142
  ERG4_ERG24   4 eyefggeigalgikiglpvlelylnaiskfealklllpksldlaelkneikeldllvfegaiwerklftvfllfyvlqavlylllpGkvveGleLs..n 100
                 e+efgg+ g+l+++ig+p+l++y++  +  ++  l lpk  ++ e+     +l +lv+ega+++ k++t++++f++++ + y++lpG+++ G +L    
  EEA23063.1 112 EFEFGGSYGTLSLMIGFPLLMYYMWIGATYYDGGLPLPKDQTIPEFL---AHLGHLVYEGAYPSLKAWTMYWVFFIFEGICYIVLPGITLAGRPLPheG 207
                 89***************************************887765...566679***************************************8767 PP

  ERG4_ERG24 101 gkkLkYkinalaslllvlaillvlqvtelfeltvlidnfvqlisvailfafalaivlYvrslkvkerkkdkqlaaggvsGnliYDffiGreLnPRl.gs 198
                 gk+L+Y + a+ s++++la+ l l+++ +f+l+++id+f++l+svail++f+++++ Y  +l            +++++G+ iYDff+G+eLnPR+ g+
  EEA23063.1 208 GKQLPYYCSAVSSFYVTLAVALGLHFSGVFKLYTIIDEFGPLLSVAILSGFLVSFIAYFSALYRGA--------QHRMTGYPIYDFFMGAELNPRMfGI 298
                 99*********************************************************9998776........8********************747* PP

  ERG4_ERG24 199 lDlkmFlelRlgllllllinlaallkqyklygkvtdslllvllaqllYvfdgvkneeavlttmDittdgFGFmLaFgdlvlvPftYslqtlYLsvh.Ps 296
                 lD+kmF+e+Rl++ +lll++++++++qy+lyg+v+ ++ ++l+a+ lY+++++k+ee +++t+D+ ++++GFmL+F++l++vP  Y+++t+YL  h P 
  EEA23063.1 299 LDFKMFFEVRLPWYILLLLTMGTAARQYELYGYVSGEVCFLLMAHFLYANACSKGEECIISTWDMYYEKWGFMLIFWNLAGVPLSYCHCTIYLANHhPD 397
                 **********************************************************************************************999** PP

  ERG4_ERG24 297 elgwst.vlvailvvlligyyiFrsansqknnFR...........tnPedpklkl..lkyiqtktGskLlvsGWyglarkinYlgDwlqslswsLatgf 381
                 ++ w    l+a+ v  l  y ++++ansqkn FR            +P++p++++  + +i+t +G+ +lvsGWyglark++Y+ D+  +l w L+tgf
  EEA23063.1 398 TYRWNPyALTALFVGYLFVYWVWDTANSQKNRFRqmergttvfrnAFPQLPWQTVhnPDVIKTPQGT-ILVSGWYGLARKVHYTCDLYFALNWGLITGF 495
                 *****96788999999****************************99******98767********97.679**************************** PP

  ERG4_ERG24 382 qsvlpyfyvlyFlvlLvhRelRDeekCkkkYGedweeYkkkvpykiipyv 431
                  s +p+fy+++F++++ hR  RD ++C++kYG++w eY+k+vpy +ipyv
  EEA23063.1 496 SSAFPWFYPVFFACMISHRCWRDIQRCRAKYGDAWTEYEKRVPYLFIPYV 545
                 *************************************************8 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (546 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       480  (0.0267723); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.60u 0.34s 00:00:00.94 Elapsed: 00:00:00.52
# Mc/sec: 3133.36
//
Query:       EEA23064.1  [L=732]
Description: RING finger domain protein (Rnf10), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.8e-07   30.9   6.1    3.2e-07   30.1   6.1    1.4  1  zf-C3HC4      Zinc finger, C3HC4 type (RING finger)
      3e-07   30.1   6.6    2.7e-06   27.1   3.1    2.3  2  zf-C3HC4_2    Zinc finger, C3HC4 type (RING finger)
    6.4e-06   26.1   1.9    6.4e-06   26.1   1.9    2.4  2  zf-RING_UBOX  RING-type zinc-finger
    1.4e-05   25.4   8.1    0.00034   20.9   8.5    2.3  2  zf-RING_2     Ring finger domain
    5.5e-05   22.9   4.7    0.00012   21.9   4.7    1.5  1  zf-C3HC4_3    Zinc finger, C3HC4 type (RING finger)
    5.9e-05   23.1   5.1    0.00042   20.4   5.6    2.1  2  zf-C3HC4_4    zinc finger of C3HC4-type, RING
    6.7e-05   22.8   4.6    0.00021   21.2   4.5    2.0  2  zf-RING_5     zinc-RING finger domain
  ------ inclusion threshold ------
       0.14   12.2   0.4        0.3   11.2   0.4    1.5  1  TerY_C        TerY-C metal binding domain
       0.15   12.8   3.0         18    6.1   0.0    3.5  3  Rxt3          Histone deacetylation protein Rxt3
       0.37   10.7   9.2        7.9    6.4   9.4    2.7  2  Prok-RING_4   Prokaryotic RING finger family 4
       0.57   10.0  10.1        3.3    7.5   9.1    2.4  2  zf-MIZ        MIZ/SP-RING zinc finger
        2.4    8.0   8.1         27    4.6   6.0    2.7  2  zf-RING_11    RING-like zinc finger
        3.8    7.9   5.8         14    6.1   5.8    2.0  1  zf-rbx1       RING-H2 zinc finger domain
        8.3    5.5   6.7         15    4.7   6.7    1.3  1  DUF1682       Protein of unknown function (DUF1682)


Domain annotation for each model (and alignments):
>> zf-C3HC4  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   30.1   6.1   2.5e-10   3.2e-07       1      41 []     189     239 ..     189     239 .. 0.93

  Alignments for each domain:
  == domain 1  score: 30.1 bits;  conditional E-value: 2.5e-10
                 -TTT-S--SS-E.E-TTS--B-CHHHHHHHHC...........TSSB--TTT CS
    zf-C3HC4   1 CpiCleeakepnelleCkHsfCskCirkilks...........rkkvkCPlC 41 
                 CpiCl +++ p  + +C+H fC++C+ +++ s            + +kCP+C
  EEA23064.1 189 CPICLGMPVAPR-MAKCGHIFCFPCLIRYMHSidddasvpekkARWKKCPIC 239
                 ************.**************************987655567***9 PP

>> zf-C3HC4_2  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.1   3.1   2.1e-09   2.7e-06       2      32 ..     189     218 ..     188     222 .. 0.93
   2 ?    4.0   0.1     0.034        44       1      11 [.     235     245 ..     235     250 .. 0.81

  Alignments for each domain:
  == domain 1  score: 27.1 bits;  conditional E-value: 2.1e-09
  zf-C3HC4_2   2 CpiCldmlkdpsvvtpCgHvfCqkCilrsLe 32 
                 CpiCl m   p ++++CgH fC  C+ r+++
  EEA23064.1 189 CPICLGMPVAP-RMAKCGHIFCFPCLIRYMH 218
                 *********99.****************986 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.034
  zf-C3HC4_2   1 kCpiCldmlkd 11 
                 kCpiC d ++ 
  EEA23064.1 235 KCPICWDTIYV 245
                 7******9984 PP

>> zf-RING_UBOX  RING-type zinc-finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.1   1.9     5e-09   6.4e-06       1      26 [.     189     216 ..     189     234 .. 0.73
   2 ?    1.3   0.2      0.27   3.5e+02       1       7 [.     236     242 ..     236     251 .. 0.82

  Alignments for each domain:
  == domain 1  score: 26.1 bits;  conditional E-value: 5e-09
  zf-RING_UBOX   1 CpIClelftdP.lvlpCGHtFCreCl..w 26 
                   CpICl     P +  +CGH+FC +Cl   
    EEA23064.1 189 CPICLGMPVAPrMA-KCGHIFCFPCLirY 216
                   *****655589433.8**********541 PP

  == domain 2  score: 1.3 bits;  conditional E-value: 0.27
  zf-RING_UBOX   1 CpIClel 7  
                   CpIC ++
    EEA23064.1 236 CPICWDT 242
                   ****986 PP

>> zf-RING_2  Ring finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   8.5   2.7e-07   0.00034       2      43 ..     188     239 ..     187     240 .. 0.75
   2 ?    6.2   0.3     0.011        13       2      14 ..     235     247 ..     234     253 .. 0.74

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 2.7e-07
   zf-RING_2   2 eCpICleelssadsvlllpCgHvfhreClerwlrssst.............CPlC 43 
                 +CpICl     +  ++  +CgH+f++ Cl r+++s                CP+C
  EEA23064.1 188 SCPICL---GMPVAPRMAKCGHIFCFPCLIRYMHSIDDdasvpekkarwkkCPIC 239
                 7****9...3333344347**********9976444447778888899999***9 PP

  == domain 2  score: 6.2 bits;  conditional E-value: 0.011
   zf-RING_2   2 eCpICleelssad 14 
                 +CpIC++ +  +d
  EEA23064.1 235 KCPICWDTIYVSD 247
                 8*****9996544 PP

>> zf-C3HC4_3  Zinc finger, C3HC4 type (RING finger)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.9   4.7   9.1e-08   0.00012       4      44 ..     188     240 ..     185     244 .. 0.92

  Alignments for each domain:
  == domain 1  score: 21.9 bits;  conditional E-value: 9.1e-08
                 B-TTTSSSBS-EEETTEEEEEE-HHHHHHHHH.............TT-B-TTT- CS
  zf-C3HC4_3   4 eCviClerprnvvllpCgHlvlCeeCaekllk.............rkkkCpiCr 44 
                  C+iCl  p    + +CgH+ +C  C+ +++              r kkCpiC 
  EEA23064.1 188 SCPICLGMPVAPRMAKCGHI-FCFPCLIRYMHsidddasvpekkaRWKKCPICW 240
                 7*******************.*********9899*******999999******6 PP

>> zf-C3HC4_4  zinc finger of C3HC4-type, RING
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.4   5.6   3.3e-07   0.00042       1      35 [.     189     223 ..     189     239 .. 0.82
   2 ?   -0.3   0.2      0.99   1.3e+03       1       6 [.     236     241 ..     236     245 .. 0.88

  Alignments for each domain:
  == domain 1  score: 20.4 bits;  conditional E-value: 3.3e-07
  zf-C3HC4_4   1 CPiCldYLekPvsleCGhsfClsCisslqkepdge 35 
                 CPiCl     P   +CGh+fC+ C+ +++++ d+ 
  EEA23064.1 189 CPICLGMPVAPRMAKCGHIFCFPCLIRYMHSIDDD 223
                 ***************************99988775 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.99
  zf-C3HC4_4   1 CPiCld 6  
                 CPiC d
  EEA23064.1 236 CPICWD 241
                 ****87 PP

>> zf-RING_5  zinc-RING finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.1   0.2       0.3   3.8e+02      34      42 ..     184     192 ..     179     194 .. 0.79
   2 !   21.2   4.5   1.7e-07   0.00021       2      42 ..     189     239 ..     188     241 .. 0.95

  Alignments for each domain:
  == domain 1  score: 1.1 bits;  conditional E-value: 0.3
   zf-RING_5  34 ekeavCpiC 42 
                 ++ a CpiC
  EEA23064.1 184 TQAASCPIC 192
                 47899**** PP

  == domain 2  score: 21.2 bits;  conditional E-value: 1.7e-07
   zf-RING_5   2 CnkCfeklskeekfyltsCgHifCekClkkll.............ekeavCpiC 42 
                 C++C        ++ + +CgHifC  Cl +++             ++ ++CpiC
  EEA23064.1 189 CPICLGMP---VAPRMAKCGHIFCFPCLIRYMhsidddasvpekkARWKKCPIC 239
                 99999999...99******************************99999****** PP

>> TerY_C  TerY-C metal binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.4   0.00024       0.3      64      97 ..     176     210 ..     155     213 .. 0.87

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00024
      TerY_C  64 lkvntseLeGapgCPhC.gnalafavCeCgkllCi 97 
                 l+v +se + a++CP C g  +a  + +Cg+++C+
  EEA23064.1 176 LQVLASEQTQAASCPIClGMPVAPRMAKCGHIFCF 210
                 67888999999****9967789************6 PP

>> Rxt3  Histone deacetylation protein Rxt3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.0      0.67   8.5e+02      32      78 ..     385     442 ..     384     477 .. 0.55
   2 ?    6.1   0.0     0.014        18      42      83 ..     524     576 ..     521     590 .. 0.59
   3 ?    3.8   0.0     0.072        93      20      83 ..     651     712 ..     637     730 .. 0.66

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.67
        Rxt3  32 DSDvvaaliHsGfirgewaedvdvslldl...............akkkakkkskeekskdes 78 
                 D ++v+   HsG+  +++  + ++ + ++               +    ++k++++ s++++
  EEA23064.1 385 DEEPVQEPDHSGLNSTAYDASSSEIVDEVaagveavdlngddhlE----SRKKEKHPSTQMK 442
                 566777778999987777666555444446666666655543221....1111111111111 PP

  == domain 2  score: 6.1 bits;  conditional E-value: 0.014
        Rxt3  42 sGfirgewaedvdvslldl...........akkkakkkskeekskdeseaekk 83 
                 +Gf++++w++ v  ++l+            +++k+++++k++ +++++e+ek+
  EEA23064.1 524 VGFLECDWTDVVVPEVLERfrpeinkrrqrNRDKEAREEKDRIRAEKEEEEKR 576
                 69************999998888654443222222222222222333333333 PP

  == domain 3  score: 3.8 bits;  conditional E-value: 0.072
        Rxt3  20 rrelWGtdvYtdDSDvvaaliHsGfirgewaedvdvslldlakkkakkkskeekskdeseaekk 83 
                  r +WGt      SD+ +  +H G ++  w +  +++ll +++++  ++ + e+s++++++   
  EEA23064.1 651 ARTVWGTAA--VQSDPHQQPLHRGPVNDGWLQGWEEDLLGQREAELLAQASAESSATAATSGGG 712
                 6899**974..5799***********99999999999998855554444433333333333222 PP

>> Prok-RING_4  Prokaryotic RING finger family 4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.6   0.3     0.046        59      27      36 ..     183     192 ..     179     195 .. 0.78
   2 ?    6.4   9.4    0.0061       7.9       1      39 [.     189     242 ..     189     248 .. 0.84

  Alignments for each domain:
  == domain 1  score: 3.6 bits;  conditional E-value: 0.046
  Prok-RING_4  27 skdlssCPlC 36 
                  +++ +sCP+C
   EEA23064.1 183 QTQAASCPIC 192
                  45677***** PP

  == domain 2  score: 6.4 bits;  conditional E-value: 0.0061
  Prok-RING_4   1 CvlCgeqekkailepCgHlvCkeCfdskdls...............sCPlCqrr 39 
                  C +C   +  ++++ CgH++C  C+    +s                CP+C   
   EEA23064.1 189 CPICLGMPVAPRMAKCGHIFCFPCLIRYMHSidddasvpekkarwkKCPICWDT 242
                  8899999999**************988877666777788899999999999765 PP

>> zf-MIZ  MIZ/SP-RING zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.0   0.2     0.068        87      31      47 ..     174     192 ..     170     195 .. 0.68
   2 ?    7.5   9.1    0.0026       3.3       4      49 ..     188     241 ..     186     242 .. 0.76

  Alignments for each domain:
  == domain 1  score: 3.0 bits;  conditional E-value: 0.068
                 HHHHH..HHHS---B-TTT CS
      zf-MIZ  31 sylel..nertetWnCPvC 47 
                 s+l++  +e+t++ +CP+C
  EEA23064.1 174 SVLQVlaSEQTQAASCPIC 192
                 55554226788889***** PP

  == domain 2  score: 7.5 bits;  conditional E-value: 0.0026
                 B-TTTSSB-SSEEEETT--SS--EEHH.HHHHHHHHS--.......-.B-TTT-- CS
      zf-MIZ   4 kCplslsrikiPvrgekCkHlqCfdle.sylelnertet.......W.nCPvCsk 49 
                  Cp+    + ++ r  kC H+ Cf +   y+++ +   +       W +CP+C+ 
  EEA23064.1 188 SCPIC-LGMPVAPRMAKCGHIFCFPCLiRYMHSIDDDASvpekkarWkKCPICWD 241
                 68885.4699999***********9762688877655545667777955****85 PP

>> zf-RING_11  RING-like zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   6.0     0.021        27       2      29 .]     189     213 ..     188     213 .. 0.81
   2 ?    2.4   0.0      0.11   1.3e+02       2      14 ..     236     248 ..     235     251 .. 0.85

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.021
  zf-RING_11   2 CsICLeefkpgqalfilpCsHtFHfkCI 29 
                 C ICL       a ++++C+H+F f C+
  EEA23064.1 189 CPICLGMP---VAPRMAKCGHIFCFPCL 213
                 88888755...45699*******99995 PP

  == domain 2  score: 2.4 bits;  conditional E-value: 0.11
  zf-RING_11   2 CsICLeefkpgqa 14 
                 C IC +++ ++++
  EEA23064.1 236 CPICWDTIYVSDT 248
                 *******987775 PP

>> zf-rbx1  RING-H2 zinc finger domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.1   5.8     0.011        14      26      54 ..     198     239 ..     177     240 .. 0.79

  Alignments for each domain:
  == domain 1  score: 6.1 bits;  conditional E-value: 0.011
     zf-rbx1  26 pvvlGeCgHaFHlhCiskWlkt.............rkvCPlc 54 
                  + + +CgH F + C+ +++++              k+CP+c
  EEA23064.1 198 APRMAKCGHIFCFPCLIRYMHSidddasvpekkarWKKCPIC 239
                 466789***************999999999998877889999 PP

>> DUF1682  Protein of unknown function (DUF1682)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.7   6.7     0.011        15     253     293 ..     542     582 ..     529     586 .. 0.71

  Alignments for each domain:
  == domain 1  score: 4.7 bits;  conditional E-value: 0.011
     DUF1682 253 klrpevlkklkktReevekklkkeaeeekaEeaqekkeeek 293
                 ++rpe+ k+ +++R++++++ k + ++ek+Ee ++  ++++
  EEA23064.1 542 RFRPEINKRRQRNRDKEAREEKDRIRAEKEEEEKRWAAARR 582
                 69999999999999999999999999999877763333222 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (732 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       955  (0.0532657); expected 358.6 (0.02)
Passed bias filter:                      501  (0.0279436); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                        14  (0.000780858); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              14  [number of targets reported over threshold]
# CPU time: 0.86u 0.34s 00:00:01.20 Elapsed: 00:00:00.59
# Mc/sec: 3710.20
//
Query:       EEA23065.1  [L=861]
Description: ubiquitin hydrolase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    8.2e-45  153.3   0.0    1.2e-44  152.7   0.0    1.2  1  UCH       Ubiquitin carboxyl-terminal hydrolase
    6.7e-11   42.3   0.0    5.1e-10   39.5   0.0    2.3  2  UCH_1     Ubiquitin carboxyl-terminal hydrolase


Domain annotation for each model (and alignments):
>> UCH  Ubiquitin carboxyl-terminal hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  152.7   0.0   1.4e-48   1.2e-44       1     250 [.     404     759 ..     404     772 .. 0.83

  Alignments for each domain:
  == domain 1  score: 152.7 bits;  conditional E-value: 1.4e-48
                 -EES-SSSTHHHHHHHHHHHTSHHHHHHHHTCHHCCSSTCCCCC-....TT.TTS.TTHHHHHHHHHHHHHH.............SH-CCEE--HHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxx.............xxxxxxxxxxxxxx RF
         UCH   1 tGlsNlGntCymnsvlQcLfsipelrdyllsleevkkesrnkkel...nesnplgkkgelakalkdlfkell.............kskskavsPkklkk 83 
                 +Gl+N+Gn CymnsvlQ+L+ + ++ ++l ++ +++++s +++ +   +++        ++++++ + ++               ++  +a+ P+ +++
  EEA23065.1 404 RGLVNTGNMCYMNSVLQILAFCVPFYQFLDYIGHRATHSFKSD-VpliDATI------MFMREFRVIDAACSedqlrmrlkhkelEEYGEAFIPEFVYE 495
                 59*****************************888888776663.33443222......23333333331111222223344655656788********* PP

                 HHHHHSGG..GTSSSTCEHHHHHHHHHHHHHHHHCC...........................HCCCHHH..HHHCCCTTSHHHHHH-EEEEE...... CS
                 xxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxx...........................xxxxxxx..xxxxxxxxxxxxxxxxxxxxx...... RF
         UCH  84 tlsklaks..fsgykqqDaqEflaflLdqlhedlnr...........................evaeekw..kkhlkrndslitdlfegqlks...... 145
                 ++++l +   ++ ++qqDaqEfl f L++lhe++                             + +++++   + +   +s+it++f+g+++s      
  EEA23065.1 496 VIRQLPRFrdMRRGHQQDAQEFLGFFLEELHEECAHalqsgtmqanadsgepseasgwlevghK-QKSAItrSSGDVDFESPITKIFGGKIRSefkvpg 593
                 ****98766689***********************************************99853.44444568889999******************** PP

                 ......................................................EEEEEEB-SEEEEEEESEEETEE...EEE--SEEB--SEEE-GGG CS
                 ......................................................xxxxxxxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxx RF
         UCH 146 ......................................................klklkrlPeiLiihlkRfsynss...ksKlntkvefpeeldlssy 187
                                                                       ++ +++lP++Li+hlkRf+y+s     +K+ +kv +p+el++ + 
  EEA23065.1 594 nknsvtlepyqplqldigspevnniidalkgltkpetlhgdfssprgpkvaatkQVFIETLPPVLILHLKRFQYDSVthgTQKIWKKVGYPLELEIPRE 692
                 **************************************************************************998899****************965 PP

                 BSS-BTTS-TCS-B.......EEEEEEEEEES.CTTSEEEEEEEECTTTTEEEEEETTEEEEE-HHCCCTT CS
                 xxxxxxxxxxxxxx.......xxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         UCH 188 laeekkkkteekkk.......YeLiavvvHsG.slssGHYvayiknekngkWykydDetvkevkeeeevls 250
                 +    +++             Y+Li+v++H+G ++s+GHY++ +++++  +W+++dD+ + +v++e +v +
  EEA23065.1 693 VFPPHRRNAM---AihgglphYRLIGVIYHHGkNASGGHYTVDVRRQDGREWIRMDDTVIRRVRSE-DVAE 759
                 5533333322...13445555************************999999************987.5554 PP

>> UCH_1  Ubiquitin carboxyl-terminal hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.8      0.18   1.6e+03     111     125 ..     254     286 ..     201     361 .. 0.39
   2 !   39.5   0.0   5.7e-14   5.1e-10       2     319 ..     405     748 ..     404     749 .. 0.77

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 0.18
                 xxxxxxxxxxxxxx..................x RF
       UCH_1 111 dqlekelketkkns..................s 125
                 +q  +e+ +t++++                  +
  EEA23065.1 254 SQAPSESDSTHHTTpsstaptnlasrsqdqaqT 286
                 222222222222111111111222221111111 PP

  == domain 2  score: 39.5 bits;  conditional E-value: 5.7e-14
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..........xxxxxxxxxxxxxxxx RF
       UCH_1   2 GLEnhivnsYlNslLQvlyfipplrnla..lshlakeckkehcLlcElgflfdmldkakglncqasnFlrals..........sipeasalglileeee 88 
                 GL n+ + +Y+Ns+LQ+l+f+ p+++++  + h a++  k +  l ++  +f  + +   + c +  +   l+           ip     +       
  EEA23065.1 405 GLVNTGNMCYMNSVLQILAFCVPFYQFLdyIGHRATHSFKSDVPLIDATIMFMREFRVIDAACSEDQLRMRLKhkeleeygeaFIP-EFVYE------- 495
                 999**********************9964489********************9999999*************94433333333111.11222....... PP

                 xxx.......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..................................xxxxxxxxxxxxxxxxxxxxxx RF
       UCH_1  89 ete.......kssaislssliqsfnrflldqlekelketkkns..................................seeesaieqllgtkaettircl 146
                           ++ ++  ++  q+f  f+l++l++e   + ++                                      es+i++++g k+ ++++  
  EEA23065.1 496 --VirqlprfRDMRRGHQQDAQEFLGFFLEELHEECAHALQSGtmqanadsgepseasgwlevghkqksaitrssgdVDFESPITKIFGGKIRSEFKVP 592
                 ..022222223344444555689************98887666999******************9999999999999999999**************99 PP

                 xxxxxxxxxxxxxxxxxxx.x.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xx....xxxxxxxxx. RF
       UCH_1 147 kCgseksrksstlvldlky.P.kpsnekkeakvtfasilksslerekttrawCekCkryqpteqrktvknlPpvLalnakle.ee....eelelwktk. 237
                       +++s+tl     y P + +   +++  ++ + lk   + e+ +  + +    +   +++  ++ lPpvL+l++k++  +     ++++wk+  
  EEA23065.1 593 -----GNKNSVTLE---PYqPlQLDI-GSPEVNNIIDALKGLTKPETLHGDFSSPRGPKVAATKQVFIETLPPVLILHLKRFqYDsvthGTQKIWKKVg 682
                 .....333333333...232444333.23344799*****************9999999999999***************9955567653789999974 PP

                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
       UCH_1 238 nwlpleiklsldedknleeklkeerekakaekeikvYeLqsvvvhigdskesghLvslvkvaekelerdppesqWylFNDfl 319
                   l+lei  ++ + +        +r+    + +   Y L++v++h g++ + gh+   v+ +        +  +W+  +D  
  EEA23065.1 683 YPLELEIPREVFPPH--------RRNAMAIHGGLPHYRLIGVIYHHGKNASGGHYTVDVRRQ--------DGREWIRMDDTV 748
                 455555555554433........334455678999************9988****8777732........235888888875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (861 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       677  (0.0377601); expected 358.6 (0.02)
Passed bias filter:                      317  (0.0176809); expected 358.6 (0.02)
Passed Vit filter:                        53  (0.0029561); expected 17.9 (0.001)
Passed Fwd filter:                         6  (0.000334653); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.94u 0.38s 00:00:01.31 Elapsed: 00:00:00.59
# Mc/sec: 4418.19
//
Query:       EEA23066.1  [L=420]
Description: ribonuclease H, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.7e-39  133.2   7.8    3.3e-19   68.9   1.7    2.3  2  Cauli_VI  Caulimovirus viroplasmin
    1.9e-37  128.6   0.0    4.2e-37  127.5   0.0    1.5  1  RNase_H   RNase H
     0.0012   18.6   0.0     0.0041   16.9   0.0    1.8  2  RVT_3     Reverse transcriptase-like


Domain annotation for each model (and alignments):
>> Cauli_VI  Caulimovirus viroplasmin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.8   0.4   1.3e-22   7.5e-19       1      44 []      48      91 ..      48      91 .. 0.98
   2 !   68.9   1.7   5.6e-23   3.3e-19       2      44 .]     114     156 ..     113     156 .. 0.98

  Alignments for each domain:
  == domain 1  score: 67.8 bits;  conditional E-value: 1.3e-22
    Cauli_VI  1 kyYAVakGrepgiYttWdecqkqvkgfpgakyKsFktraeAeaf 44
                k+YAV++G  pgiY++W++c +qv+gf+ga+++sF++++eA+ f
  EEA23066.1 48 KFYAVKEGFRPGIYYNWNDCLAQVTGFKGAVFQSFPSLEEANSF 91
                9****************************************988 PP

  == domain 2  score: 68.9 bits;  conditional E-value: 5.6e-23
    Cauli_VI   2 yYAVakGrepgiYttWdecqkqvkgfpgakyKsFktraeAeaf 44 
                 +YAV++Gr pg+Y++W+e+q+q+kgf+ ++yK+F+tr+eAe+f
  EEA23066.1 114 FYAVQRGRVPGVYSNWAEAQEQIKGFTRPRYKKFDTRKEAEEF 156
                 9*****************************************9 PP

>> RNase_H  RNase H
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.5   0.0     7e-41   4.2e-37       5     142 ..     242     386 ..     239     387 .. 0.83

  Alignments for each domain:
  == domain 1  score: 127.5 bits;  conditional E-value: 7e-41
                 EEEEEEEEECT.TTCEEEEEEECTT....EEEEEEEC.CCCHHHHHHHHHHHHHHHTT.SCSEEEEEES-HHHHHHHHCCCHHHHHTTSSSETTSSBHT CS
     RNase_H   5 vvYtDGsclgn.pgeggagavlykeg..arnisaple.eaqtnnraELsAvieaLkalksdekvniytDSkYvvkgitqwvhrwkknawkttseqkpvk 99 
                  +YtDGs+lgn ++ ++ag+++y++   +rn+s+pl+ ++qtn+raEL+A+i aL+ + ++  v+i+tDS+Y ++ +t+w  +w++n+w+t++ + pv 
  EEA23066.1 242 RIYTDGSSLGNgKKVAQAGVGVYFGPndTRNVSEPLKgHRQTNQRAELTAIIRALEIAPRHRPVTIVTDSRYSIDCVTNWFRKWIRNNWQTSDGK-PVE 339
                 69*********6666699997766654466**************************779******************************666555.*** PP

                 THHHHHHHHHCHC.....SSEEEEEE-SCCSSSTHHHHHHHHHHHHHH CS
     RNase_H 100 nkdlaellkelak.....kkkvqlkwvkgHaGvpkgNemaDrlAkeaa 142
                 nkdl++ +   ++     k++ +++wvkgH+ +  gNe+aDrlA+++a
  EEA23066.1 340 NKDLIQSILVKINerdslKVTTTFEWVKGHNRD-AGNEEADRLAVNGA 386
                 *88887653322211113566789*********.5**********997 PP

>> RVT_3  Reverse transcriptase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.1   0.0      0.52   3.1e+03      19      50 ..     106     137 ..      97     140 .. 0.78
   2 !   16.9   0.0   6.9e-07    0.0041      20      78 ..     265     320 ..     245     332 .. 0.77

  Alignments for each domain:
  == domain 1  score: -2.1 bits;  conditional E-value: 0.52
       RVT_3  19 irdsnGevllagaeklqgkasveeAElqALlr 50 
                  r++nG +  a+++   ++  +  AE+q  + 
  EEA23066.1 106 TRNENGTRFYAVQRGRVPGVYSNWAEAQEQIK 137
                 59999999999998877777778888876555 PP

  == domain 2  score: 16.9 bits;  conditional E-value: 6.9e-07
       RVT_3  20 rdsnGevllagaeklqgkasveeAElqALlrGLqlalklgirrlvvegDsktvvqllng 78 
                   +n+ + ++   k +++++++ AEl+A++r+L++a ++  r++++ +Ds+  ++ +++
  EEA23066.1 265 FGPNDTRNVSEPLK-GHRQTNQRAELTAIIRALEIAPRH--RPVTIVTDSRYSIDCVTN 320
                 55566555555555.8999*****************997..899999999999998887 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (420 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       514  (0.0286686); expected 358.6 (0.02)
Passed bias filter:                      440  (0.0245412); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.67u 0.32s 00:00:00.99 Elapsed: 00:00:00.52
# Mc/sec: 2416.15
//
Query:       EEA23067.1  [L=581]
Description: Na/H antiporter, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    4.9e-47  160.5  24.1    6.2e-47  160.2  24.1    1.0  1  Na_H_Exchanger  Sodium/hydrogen exchanger family
  ------ inclusion threshold ------
        7.1    6.7   6.7         13    5.9   0.2    2.8  3  Vma12           Endoplasmic reticulum-based factor for assemb


Domain annotation for each model (and alignments):
>> Na_H_Exchanger  Sodium/hydrogen exchanger family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  160.2  24.1     7e-51   6.2e-47       3     376 ..      16     435 ..      14     436 .. 0.87

  Alignments for each domain:
  == domain 1  score: 160.2 bits;  conditional E-value: 7e-51
                     HHHHHHHHHHH..H.HHHTTSXHHHHHHHHHHHHTTTTTS...............HHHCHCCHHHHCHHCCHHHHCTCGCCTGCCTHHHHHHHHH CS
  Na_H_Exchanger   3 llillallvgl..l.arrlklpeivgliiaGlllGpsglglieps..........eedlevlselglilllFlaGleldlrelrknlksilllal 84 
                     l++++++++++  l  +r++l+e ++  +aG+ + p+  ++i+p+          + ++ ++ +l+l ++l  aG+ l+ r+l+  +ks  ll+ 
      EEA23067.1  16 LGGFITIFGLVsyLfKERFYLSEALISTLAGITFSPHAANFIKPMdyamgsqsnlDAITMYFTRLVLGVQLVIAGVQLPGRYLQTEWKSLALLLG 110
                     556655555557766******************************************************************************** PP

                     HHHHHHHHHHHHHHH.HHTXTTCHHHHHHHHHHHTSSXHHHHHHHC....CCCTSTCCCCCCHHHHHHHHHHHCCCCCHHHHHHTX.......XX CS
  Na_H_Exchanger  85 lgvlitvvliGlllylllilgiplleallfgailsatdpvvvlailk...eegrvperlgtlllgesvlnDavavvllavllalak.......ee 169
                     +g++++++ +Gll++  l+++i++++al++ga++++tdpv+  +i+k     + +p+ l +++++es+ nD+++ ++l+++l l+k       ++
      EEA23067.1 111 PGMAVMWLSSGLLIWS-LVPNISFIQALAVGACVTPTDPVLSNSIVKgkfADKNIPRPLQRIIVAESGANDGLGYPFLFLALYLMKytqgpefSG 204
                     *********9**9996.79****************************99977778******************************9999999888 PP

                     XXTSSSTSXHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS....CTHHHHHHHHHHHHHHHHHHHHHTSXXXHHHHHHHHHHHHH.HHHHHTTHHH CS
  Na_H_Exchanger 170 aggetslllllliflvvavgglllglvigwllrlitrft....dddrelevllvlllallaallaellgvsgilgaflaGlvls.eyefsnklse 259
                      gg + +l++  +++++++++++ g+++gwl+ ++++++      dre+++++++ l l++ ++  l+g +++l++f+aG +++ + +f+ ++  
      EEA23067.1 205 GGGKAIALWIYETLIYEIALSVVYGAAVGWLSMKLLHWAeekrYVDRESFLVFAISLGLFIMGTCGLIGTDDLLACFIAGNAFTqDDWFRLETMD 299
                     99999999*******************************99555566666666666666667777778*****************9999999555 PP

                     H.HHHHHHHHHHHHHHHHHHHHSXHHHHHX..XHHHHHHHHHHHHHHHTHHHHHHHHHTTTX..SSXHHHHHHCCCCSS.BHHHHHHHHHHHHHH CS
  Na_H_Exchanger 260 k.lesfreglfnplfFvlvGlsldlkvlnn..hlsvlilvllilvaillgrilavflllrll..glslrealiigfgglqrgavalalaalgpal 349
                     + l ++++ l+n ++Fv +G+  +++++ +   +   +l++l ++++l++r+++vf++ +++  + + ++al++gf g  +g  a+  +++ ++ 
      EEA23067.1 300 DsLQPTIDMLLNLAIFVWFGAVCPWALFAHndIIPIYRLIVLGILILLFRRLPVVFVMHKYIhqIEQVSQALFVGFFGP-IGVGAVFYLSVCRQF 393
                     55**********************8888768866666777777777778*************8668889******6555.555555555666666 PP

                     XHHHH...............TT.SSTTTCSTSXHHHHHHHHHH CS
  Na_H_Exchanger 350 gllar...............el.yallivvvlftvlvqGlslk 376
                      ll++               e+ y ++ + v+++++v+Gls++
      EEA23067.1 394 -LLEEiivdgevradavrtaEVtYIVVWFLVICSIFVHGLSVP 435
                     .3333444466666666666888*****************986 PP

>> Vma12  Endoplasmic reticulum-based factor for assembly of V-ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.2    0.0014        13      81     104 ..       9      32 ..       6      88 .. 0.86
   2 ?    4.0   0.1    0.0055        50      78     105 ..     217     250 ..     215     271 .. 0.72
   3 ?   -2.8   0.2      0.66   5.9e+03      80     135 ..     309     364 ..     296     381 .. 0.58

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.0014
       Vma12  81 lNiliSvvavffavwialrsartp 104
                 +Ni++Sv++ f++++ +++++++ 
  EEA23067.1   9 FNIVCSVLGGFITIFGLVSYLFKE 32 
                 8**************999998654 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.0055
       Vma12  78 ilvlNiliSvvavffavwialrsartp......s 105
                 +l+  i +Svv  ++++w  ++ +         +
  EEA23067.1 217 TLIYEIALSVVYGAAVGWLSMKLLHWAeekryvD 250
                 6899**************9888763334455554 PP

  == domain 3  score: -2.8 bits;  conditional E-value: 0.66
       Vma12  80 vlNiliSvvavffavwialrsartpslpvrvllslvvallVgvAEvvvyakylrkv 135
                  lN+ i v + +++ w +  +    +    ++l++++ l   +  v+v+ ky++++
  EEA23067.1 309 LLNLAIFVWFGAVCPWALFAHNDIIPIYRLIVLGILILLFRRLPVVFVMHKYIHQI 364
                 56666666666666666555543333333333444444444444455555555544 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (581 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       512  (0.0285571); expected 358.6 (0.02)
Passed bias filter:                      303  (0.0169); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.29s 00:00:00.89 Elapsed: 00:00:00.48
# Mc/sec: 3629.73
//
Query:       EEA23068.1  [L=582]
Description: cytochrome P450, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.6e-05   22.7   0.1      0.013   14.3   0.0    2.8  2  p450      Cytochrome P450
  ------ inclusion threshold ------
      0.013   14.6   0.0       0.02   13.9   0.0    1.2  1  VESA1_N   Variant erythrocyte surface antigen-1


Domain annotation for each model (and alignments):
>> p450  Cytochrome P450
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    4.9   0.0     0.001         9       3      63 ..      63     122 ..      62     204 .. 0.77
   2 !   14.3   0.0   1.4e-06     0.013     283     393 ..     357     500 ..     349     514 .. 0.73

  Alignments for each domain:
  == domain 1  score: 4.9 bits;  conditional E-value: 0.001
                 SESEHHCCHCHHHHTTTCCHHHHHHHHHHHH-SEEEEEETTEEEEEEESHHHHHHHHCTST CS
        p450   3 gptplplvgnllqlgrkeelhevlrklqkkygpifrlklgskpvvvlsgpeavkevlikkg 63 
                  p+++p +g+++ +  ++++   l+  +   +p++ l++g ++  ++++p++++ + ++++
  EEA23068.1  63 LPYWIPGLGHAFSYF-WRHRDFLLDARKTMNEPVVALQMGLQTQYLVYSPDMIRTLIKNGD 122
                 578899999999997.888888788888888***********************9998875 PP

  == domain 2  score: 14.3 bits;  conditional E-value: 1.4e-06
                 HHHHHHHHHSHHHHHHHHHHHHHHCCTTT.................T-HHHHCCT-HHHHHHHHHHHHH..SCSSTTEEE.....EESSSCEEETT... CS
        p450 283 swaLyeLaknPevqeklreEidevlgdkr.................eptyddlqklpyldavikEtLRl..hpvvplllp.....Revtkdvvirg... 354
                 +w ++++  +Pe+ +++r+Ei  +++ +r                   t++ ++   +l+a+  Et Rl   pv++ +l+      e ++d +i g   
  EEA23068.1 357 FWNILHIFSDPELLSAVRKEIAPHIKVSRsdpkvtglpiaeppilsIDTEKLFTGCVLLKATYAETIRLdaNPVSYRQLTanltlTESKEDATIFGrds 455
                 688888888888888888888888865556788888888888777666777777888888888888887432444433330000134445888877777 PP

                 ......EEE-TT-EEEEEHHHHHT-TTTSSSTTS--GGGGB-TTS CS
        p450 355 ......ylipkGtevivnlyalhrdpevfpnPeeFdpeRFldekg 393
                       y + k+++  +  +a h d  ++ + ++F p+RFl++ +
  EEA23068.1 456 ekhprsYQFFKDDILGLASGAHHVDSRYYRDSKRFTPHRFLSRAA 500
                 77778899*********************************9977 PP

>> VESA1_N  Variant erythrocyte surface antigen-1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0   2.2e-06      0.02     395     445 ..      27      76 ..       9      84 .. 0.84

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 2.2e-06
     VESA1_N 395 lGalfklyilscayftGlqkksstekstaktPktireilywlsalPysqay 445
                 l a+f + ils    tGlq + s  +s+  +P+ +r++ yw+  l ++ +y
  EEA23068.1  27 LVAIFIFSILSTRAITGLQSQ-SHADSADGEPRRVRKLPYWIPGLGHAFSY 76 
                 569999***************.677888899***********998776655 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (582 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       395  (0.0220313); expected 358.6 (0.02)
Passed bias filter:                      374  (0.0208601); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.28s 00:00:00.85 Elapsed: 00:00:00.45
# Mc/sec: 3886.74
//
Query:       EEA23069.1  [L=259]
Description: phosphatase-like protein (PTPLA), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.9e-59  198.7   5.0    6.7e-59  198.3   5.0    1.2  1  PTPLA     Protein tyrosine phosphatase-like protein, PTPLA


Domain annotation for each model (and alignments):
>> PTPLA  Protein tyrosine phosphatase-like protein, PTPLA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  198.3   5.0   3.8e-63   6.7e-59       1     163 [.      70     253 ..      70     254 .. 0.97

  Alignments for each domain:
  == domain 1  score: 198.3 bits;  conditional E-value: 3.8e-63
       PTPLA   1 QtlavlEvlhallglvrspvlttamQvasRllvvwgvvelfpe.................................lqtkspavtllllaWsvtEviRY 66 
                 Q+la lE++h+l+g+vr+pv+ttamQvasR+ vvwg++++f+e                                 +q  + a++ +++aW++tE+iRY
  EEA23069.1  70 QSLAGLEIFHSLIGVVRAPVITTAMQVASRFAVVWGIMYAFREgsglydsvlskyfpdipfvqqsvgeglmgvpgkVQYGDFAFFGCMFAWGITECIRY 168
                 99************************************************************************9999999****************** PP

       PTPLA  67 sfyalklslgkvpklltwlRYtlfivLYPlGvasElvliyaalpvlkeskklsielpnklnfsfsykyflllllllyvpglyvlythmlkqRrkvlg 163
                 +f++l+l   +vp++++wlRY++f+vLYP+G++sE++++y +l+++++              + +yk+fl+l+l +y+pg+y+lythm++qRr+v++
  EEA23069.1 169 GFFVLQLGGLSVPGWWQWLRYNTFFVLYPIGISSECFFMYLSLDHAEKYV------------HEYYKWFLVLVLGIYIPGSYILYTHMMAQRRRVMR 253
                 *******5589*********************************999655............789******************************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (259 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       516  (0.0287802); expected 358.6 (0.02)
Passed bias filter:                      327  (0.0182386); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.44u 0.26s 00:00:00.70 Elapsed: 00:00:00.42
# Mc/sec: 1837.26
//
Query:       EEA23070.1  [L=442]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
      2e-16   60.7   7.8    2.1e-16   60.6   4.7    2.2  2  Adaptin_binding  Alpha and gamma adaptin binding protein p34


Domain annotation for each model (and alignments):
>> Adaptin_binding  Alpha and gamma adaptin binding protein p34
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.8   0.0     0.039     7e+02      56      71 ..     181     196 ..      60     271 .. 0.65
   2 !   60.6   4.7   1.2e-20   2.1e-16       1     121 []     314     437 ..     314     437 .. 0.85

  Alignments for each domain:
  == domain 1  score: 0.8 bits;  conditional E-value: 0.039
  Adaptin_binding  56 qpastepdksaaeses 71 
                      q+a +e++k+aae+e+
       EEA23070.1 181 QTAIEEDSKDAAERED 196
                      3333333333333222 PP

  == domain 2  score: 60.6 bits;  conditional E-value: 1.2e-20
  Adaptin_binding   1 ekqGieRirEaLethmWsglelkkqtaslsnrnaslet...................eadeaqlekeeeeqdpsqpastepdksaaesesadae 75 
                      e +G+ R++E+L+th+W+ +   ++ ++ +   ++                      e+d++++e+  ++ +++ ++ +++d+ ++e++     
       EEA23070.1 314 ELEGLPRLKEVLSTHEWTASSSRDVGDEDD---DD--DimaflnsetrgeestgfkfEVDQLEREMMGLRFAINGGDNEDDDAHEEEED----- 397
                      56899**************88877654322...22..123467889******************************9887777655555..... PP

  Adaptin_binding  76 flfggdeaarledlesllsklqqakdnvrnlpdeeRkkeAakvald 121
                             + ++e+le l+ +++++kd+++ lp+ +Rk++Aak+++d
       EEA23070.1 398 ------PELQVENLEALMMRMRAIKDMSSDLPESKRKAFAAKAVKD 437
                      ......58***********************************986 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (442 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       567  (0.0316247); expected 358.6 (0.02)
Passed bias filter:                      362  (0.0201908); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.43
# Mc/sec: 3110.04
//
Query:       EEA23071.1  [L=116]
Description: small nuclear ribonucleoprotein SmD3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.7e-15   56.4   0.2    2.3e-15   56.0   0.2    1.2  1  LSM       LSM domain
  ------ inclusion threshold ------
      0.091   12.9   0.1       0.16   12.1   0.1    1.4  1  SM-ATX    Ataxin 2 SM domain


Domain annotation for each model (and alignments):
>> LSM  LSM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   56.0   0.2   2.5e-19   2.3e-15       2      66 ..      14      77 ..      13      78 .. 0.97

  Alignments for each domain:
  == domain 1  score: 56.0 bits;  conditional E-value: 2.5e-19
                HHHHTTTSEEEEEETTSEEEEEEEEEEETTSEEEEEEEEEEETTETEEEEEEEEEEEGGGEEEEE CS
         LSM  2 flkklinkkvtvelkngrelrGtLkgfDqfmNlvLedveetlkdkkekrklglvliRGnnivlis 66
                +l++ +++ vt+e ++g+++rG+L + +++mN++L+d+++t +d+ ++ +l++v+iRG+++++ +
  EEA23071.1 14 LLNEAQGHVVTLEITSGQVYRGKLLEAEDNMNVQLKDITVTARDG-RVSHLDQVYIRGSHVRFFI 77
                799******************************************.****************976 PP

>> SM-ATX  Ataxin 2 SM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.1   1.8e-05      0.16       7      44 ..      14      49 ..      12      67 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 1.8e-05
                HHHTTTTSEEEEEETTS-EEEEEEEEE-T..T--EEEE CS
      SM-ATX  7 lltslvGkevevtvknGevyeGifstvslekdfsvvLk 44
                ll+   G++v++++++G vy+G +  +    +++v Lk
  EEA23071.1 14 LLNEAQGHVVTLEITSGQVYRGKLLEAED--NMNVQLK 49
                678889****************8888887..7777777 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (116 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       349  (0.0194657); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        27  (0.00150594); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.36u 0.26s 00:00:00.62 Elapsed: 00:00:00.40
# Mc/sec: 870.28
//
Query:       EEA23072.1  [L=114]
Description: small nuclear ribonucleoprotein SmD3, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    1.3e-12   47.3   0.4    1.8e-12   46.8   0.4    1.2  1  LSM       LSM domain


Domain annotation for each model (and alignments):
>> LSM  LSM domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.8   0.4     1e-16   1.8e-12       2      66 ..      14      75 ..      13      76 .. 0.95

  Alignments for each domain:
  == domain 1  score: 46.8 bits;  conditional E-value: 1e-16
                HHHHTTTSEEEEEETTSEEEEEEEEEEETTSEEEEEEEEEEETTETEEEEEEEEEEEGGGEEEEE CS
         LSM  2 flkklinkkvtvelkngrelrGtLkgfDqfmNlvLedveetlkdkkekrklglvliRGnnivlis 66
                +l++ +++ vt+e ++g+++rG+L   +++mN++L+d+++t +d+ ++ +l++v+iRG+++++ +
  EEA23072.1 14 LLNEAQGHVVTLEITSGQVYRGKLL--EDNMNVQLKDITVTARDG-RVSHLDQVYIRGSHVRFFI 75
                799*********************6..7*****************.****************976 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (114 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       327  (0.0182386); expected 358.6 (0.02)
Passed bias filter:                      292  (0.0162865); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.36u 0.27s 00:00:00.63 Elapsed: 00:00:00.42
# Mc/sec: 808.48
//
Query:       EEA23073.1  [L=262]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.4e-54  184.2   0.0    1.7e-54  183.9   0.0    1.1  1  PGP_phosphatase  Mitochondrial PGP phosphatase
    1.3e-05   25.1   0.0    2.5e-05   24.3   0.0    1.4  1  Hydrolase_like   HAD-hyrolase-like
    0.00052   20.4   0.1       0.19   12.0   0.0    2.2  2  Hydrolase        haloacid dehalogenase-like hydrolase


Domain annotation for each model (and alignments):
>> PGP_phosphatase  Mitochondrial PGP phosphatase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  183.9   0.0   2.8e-58   1.7e-54       2     168 .]      10     221 ..       9     221 .. 0.94

  Alignments for each domain:
  == domain 1  score: 183.9 bits;  conditional E-value: 2.8e-58
  PGP_phosphatase   2 sa.tlavlkllknpslvlPhltvptfrqlpieig.....................kkkektikavvlDKDnclaapkedkvaeeikekleelr. 72 
                      +a +l+v++llk+ps +lP+lt+ptf +lp++ig                     ++++++ika+vlDKDn+l++p+++++++++ +kle+lr 
       EEA23073.1  10 QAfNLTVSTLLKQPSHFLPNLTIPTFLELPEQIGqhlassssssssqttesktngERRTPKIKALVLDKDNTLCPPHTTTLPKAYLDKLEQLRt 103
                      677899***********************************************999999*********************************** PP

  PGP_phosphatase  73 ........evypeksilivSNsaGssdd..kdaekaealekktg...ipVlrhk..........ekKPgcaeevleyfkerkvveeadeiavvg 143
                              ++ p+  ++ivSN+aGs++d  k +++a++le+k++   ipV+r +          ++KP+c+ +vl++f+er+v++++de++vvg
       EEA23073.1 104 sptspfniHTNPD-GVMIVSNTAGSRPDvpKYENEARTLEEKLKylrIPVFRVQpssgiegaggKRKPFCGPDVLAWFRERGVINQPDEVVVVG 196
                      ******7666677.9***********962234567788888877788*********************************************** PP

  PGP_phosphatase 144 DRllTdvllanmmGslgvwlrdgve 168
                      DRl+Td l+a++mGs++vw++dgv+
       EEA23073.1 197 DRLGTDTLMAAQMGSWSVWCKDGVT 221
                      ***********************95 PP

>> Hydrolase_like  HAD-hyrolase-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.3   0.0   4.2e-09   2.5e-05      20      55 ..     188     223 ..     167     236 .. 0.88

  Alignments for each domain:
  == domain 1  score: 24.3 bits;  conditional E-value: 4.2e-09
                     -GGGEEEEES-TTTHHHHHHHCT-EEEEESSSSS-T CS
  Hydrolase_like  20 dpeevlmiGDrlatDiagAnnaGwksvLVltGvtrp 55 
                     +p+ev+++GDrl tD ++A ++G  sv  + Gvt+ 
      EEA23073.1 188 QPDEVVVVGDRLGTDTLMAAQMGSWSVWCKDGVTHS 223
                     589******************************865 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.0   0.0   3.2e-05      0.19       1      42 [.      71     111 ..      71     149 .. 0.83
   2 !    6.3   0.1    0.0018        11     188     210 .]     187     210 ..     175     210 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 3.2e-05
                 SSEEEEESBTTTBCHHHHHHHHHHHHCHHHHHHHHHH..HHCHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxx RF
   Hydrolase   1 iktvvfDkdGTLttgepsvedvivsaalalaaaletg..sehpi 42 
                 ik++v+Dkd+TL+   p +++++++a l+  ++l+t+  s+  i
  EEA23073.1  71 IKALVLDKDNTLC---PPHTTTLPKAYLDKLEQLRTSptSPFNI 111
                 89***********...9999999999999999999998855444 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0018
                 STGGGEEEEESSHH.HHHHHHHTT CS
                 xxxxxxxxxxxxxx.xxxxxxxxx RF
   Hydrolase 188 gkpeevamVGDgvn.DaaalaaAg 210
                  +p ev++VGD++  D  ++a++g
  EEA23073.1 187 NQPDEVVVVGDRLGtDTLMAAQMG 210
                 5799*****************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (262 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       611  (0.0340789); expected 358.6 (0.02)
Passed bias filter:                      503  (0.0280551); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.41
# Mc/sec: 1912.41
//
Query:       EEA23074.1  [L=589]
Description: homeobox transcription factor (RfeB), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    7.1e-20   70.6   5.1    1.6e-19   69.5   5.1    1.6  1  Homeodomain  Homeodomain
    0.00071   19.4   0.6     0.0017   18.2   0.6    1.6  1  Homeobox_KN  Homeobox KN domain


Domain annotation for each model (and alignments):
>> Homeodomain  Homeodomain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   69.5   5.1   1.8e-23   1.6e-19       2      56 ..      56     110 ..      55     111 .. 0.97

  Alignments for each domain:
  == domain 1  score: 69.5 bits;  conditional E-value: 1.8e-23
                  T-SSSS-HHHHHHHHHHHHHSSS-SHHHHHHHHHHHTS-HHHHHHHHHHHHHHHH CS
  Homeodomain   2 rkRttftkeqleeLeklFeenrypsaeereeLAkklgLeerqVkvWFqNrRakek 56 
                  +kR++ t++ql +Le++F++n++p+a+ re++A++++++er V++WFqNrRak k
   EEA23074.1  56 QKRQRATQDQLVTLEQEFNKNPTPTAAVRERIAQEINMTERSVQIWFQNRRAKIK 110
                  69***************************************************88 PP

>> Homeobox_KN  Homeobox KN domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.6   1.9e-07    0.0017       7      39 ..      75     107 ..      72     108 .. 0.95

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 1.9e-07
  Homeobox_KN   7 hnPYPseedKeeLlkeTglsvkqitnWFINaRr 39 
                  +nP P+++ +e++++e +++ + ++ WF N R+
   EEA23074.1  75 KNPTPTAAVRERIAQEINMTERSVQIWFQNRRA 107
                  6999**************************996 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (589 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1076  (0.0600145); expected 358.6 (0.02)
Passed bias filter:                      584  (0.0325729); expected 358.6 (0.02)
Passed Vit filter:                        60  (0.00334653); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.65u 0.28s 00:00:00.93 Elapsed: 00:00:00.44
# Mc/sec: 4042.93
//
Query:       EEA23075.1  [L=435]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      2e-51  174.8   9.9    2.5e-51  174.5   9.9    1.1  1  Polysacc_lyase  Polysaccharide lyase
     0.0009   19.3   0.8     0.0015   18.5   0.8    1.5  1  Lactamase_B     Metallo-beta-lactamase superfamily
  ------ inclusion threshold ------
      0.067   12.7   0.1       0.12   11.9   0.1    1.3  1  Lactamase_B_2   Beta-lactamase superfamily domain


Domain annotation for each model (and alignments):
>> Polysacc_lyase  Polysaccharide lyase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  174.5   9.9   4.2e-55   2.5e-51       1     209 [.      27     241 ..      27     242 .. 0.96

  Alignments for each domain:
  == domain 1  score: 174.5 bits;  conditional E-value: 4.2e-55
  Polysacc_lyase   1 vetGdlspwatvqe.aagklqrvkdvsrsGkyalkvevkpddnsvegkeRsEvledyatskqgsevwYgfsvylpedfpsdakqsyiiaQwhgep 94 
                     v+tG+ls+w++++  ++g++++v+dv+++G++alk+++ +d  s  g+++sE  + +++ k g++ +Ygf+++l+ed++ +++qsy+iaQ+++++
      EEA23075.1  27 VNTGTLSGWSSQNIeHKGSINQVTDVVYNGTTALKFTQVYD-SSYTGRYHSEKAKTQVY-KLGDQGFYGFAFRLQEDWQASPAQSYNIAQFIADF 119
                     589*******9999***************************.6667*************.*********************************** PP

  Polysacc_lyase  95 sg..eddgsPplalgirggklylrarsdknssekktstkakklnlaplpkgkWhdfavevkwssdgsGeievwldgkkvvdqkgviitkddddgp 187
                      +  +dd++P++++++ g++l +r++ ++ ++++ +++k     l+++++g+Wh+++++++w+sd+ G++++w+dg kvv+++++ +  dd   +
      EEA23075.1 120 TDtgCDDWMPSSMVWVIGDQLATRVKFGSICAQQIQEWK----GLVTVTPGEWHKIVIQANWQSDNAGYYKMWYDGAKVVEEYNLPTMIDDARPF 210
                     ******************************977777766....*****************************************998888888** PP

  Polysacc_lyase 188 yfKvGiYrn.........gstterviyyDev 209
                      f+vGiY+n         g++++r+i++D+v
      EEA23075.1 211 DFHVGIYANgwhdqgenlGTQNTREIWIDSV 241
                     *****************************87 PP

>> Lactamase_B  Metallo-beta-lactamase superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.5   0.8   2.6e-07    0.0015      33      67 ..     316     356 ..     299     424 .. 0.82

  Alignments for each domain:
  == domain 1  score: 18.5 bits;  conditional E-value: 2.6e-07
                  H......HHHHHTSGGGGEEEEE-SBSSHHHHTTGGGCTTH CS
  Lactamase_B  33 l......elaalglkpkdvdavilTHlHlDHiGglgglvea 67 
                  +      ++   g ++k v av + HlHlDHi+gl+++ ++
   EEA23075.1 316 DeikllaAIMPTGNGIKTVNAVSIGHLHLDHISGLEHFLDT 356
                  33335668888999************************986 PP

>> Lactamase_B_2  Beta-lactamase superfamily domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.9   0.1     2e-05      0.12      26      64 ..     329     364 ..     306     372 .. 0.84

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 2e-05
                    --..SEEEEE-SS--HHHHGGGGCCCCC--EEEEEEEEH CS
  Lactamase_B_2  26 delppidaVllthaHyDHlaglltlrelrpkklplyapk 64 
                    + ++ ++aV + h H DH+ gl ++     +++ +y+++
     EEA23075.1 329 NGIKTVNAVSIGHLHLDHISGLEHFLD---TDVSIYVQE 364
                    5677899****************9999...457788765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (435 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       378  (0.0210832); expected 358.6 (0.02)
Passed bias filter:                      265  (0.0147805); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.54u 0.25s 00:00:00.79 Elapsed: 00:00:00.45
# Mc/sec: 2934.23
//
Query:       EEA23076.1  [L=641]
Description: glucan 1,4-alpha-glucosidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
     3e-100  336.1   0.2   3.8e-100  335.8   0.2    1.1  1  Glyco_hydro_15  Glycosyl hydrolases family 15
    1.5e-35  121.0   1.5    2.2e-35  120.4   0.4    1.9  2  CBM_20          Starch binding domain
  ------ inclusion threshold ------
        4.1    6.4   5.9        6.4    5.8   5.9    1.3  1  SAP130_C        Histone deacetylase complex subunit SAP130 C-


Domain annotation for each model (and alignments):
>> Glyco_hydro_15  Glycosyl hydrolases family 15
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  335.8   0.2  6.3e-104  3.8e-100       3     447 ..      46     458 ..      44     459 .. 0.98

  Alignments for each domain:
  == domain 1  score: 335.8 bits;  conditional E-value: 6.3e-104
                     HHHHHHHCBCSTTSSBTTS-TT-B-S-S-BSSSB--SEEHHHHHHHHHHHH.......HHHHHTTT-HCCHHHHHHHHHHHHHHCTS-BTTB-TT CS
  Glyco_hydro_15   3 rldlylrnvktlilleqnpvtGlliASpstsdpDYrytWvRDsvyvilavwglgyrdedrakayeleqslvklmrglleamvrqagkvekfketq 97 
                     +l+++l+n+++ ++   ++ +G++iASpst++p Y+ytW+RDs++++++++        + + ++ + sl++ ++++++a++  +  ++++++ +
      EEA23076.1  46 SLNGILANIGSSGAYSASAKPGVVIASPSTNNPNYYYTWTRDSALTLKVLI--------DLFGNG-NLSLQTVIEEYINAQAYLQTVSNPSGDLS 131
                     578999*********************************************........889999.***************************** PP

                     SCGGGG--EE-TTS-B--S-..-S--BTTHHHHHHHHHHHH....HCTT..HCHCCCCHHHHTHHHHHHHHHHHTTS-EE-TTS--ECEEHH..H CS
  Glyco_hydro_15  98 stkgLhakyftktgstvvGddewghlQlDatslyllalaqm....tasg..lqiistldevafvqnlvdYieaayktpdfglWEenqgeselnas 186
                     s+ gL +++++++ s+++G   wg++Q+D+++l+++al+++    +++g  ++++++++++  v+n+++Y+ +++++++f+lWEe+++ s++  +
      EEA23076.1 132 SGAGLAEPKYNVDMSPFTGG--WGRPQRDGPALRAIALIEFgnwlIDNGysSYAVNNIWPI--VRNDLSYVSQYWSQSGFDLWEEVNSMSFF--T 220
                     ********************..***************************************..*****************************..* PP

                     HHHHHHHHHHHHHHHHHCT-HHHHCCHHHHHHHHHHHHHSTTT..GGGEETTCCECECSCH.....HHHTTS--S-BCHHHHHHHHCS-TTS-TT CS
  Glyco_hydro_15 187 svgmakAlleaideadlfgakgdaqlvektkdeilnklqgkygckrgfwplfntylildgsfaedkeqvqeyrealdasllllpelyfvpaddvd 281
                      + +++Al+++  +a ++g  ++++++++++++il+++       + fw+  + y++++             r+++d++++l  +++f+p++ +d
      EEA23076.1 221 VANQHRALVQGSTFAARVG--ASCSWCDSQAPQILCYM-------QTFWT--GSYINANTG---------GGRSGKDSNTVLTTIHTFDPEATCD 295
                     *******************..9****************.......99**9..667777777.........67*********************** PP

                     -TT-TTTSHHHHHHHHHHHHHHHHHSGGGTT-STTS...--SBTT--CGSSSBSCT--BHHHHHHHHHHHHHHHHHHHHHTE-EEEECCCHHHHH CS
  Glyco_hydro_15 282 eeyqnpqsprllaqslyildsllsegflavgeldpl...vrRysedvkpdklglsGrpyylctlwtvetlldelyekagkgrlwglvryalglle 373
                     + +++p+spr+la++++++ds++s + +++g  ++    v+Ry+ed+++      G+p++l++l+++e+l+d++y++++ g+ +++++++l++++
      EEA23076.1 296 DVTFQPCSPRALANHKVYTDSFRSIYGVNSGIAQGVavsVGRYPEDSYY-----GGNPWFLSNLAAAEQLYDAIYQWNKIGS-ITITSTSLAFFK 384
                     ********************************999999**********9.....**************************99.************ PP

                     HHTTTTTGGGSSEEE.TCHHHHHHHHHHHHHHHHHHHHHH.S-TTS---SEE-TTT--EESSTT-HHHHHHHHHHH CS
  Glyco_hydro_15 374 klveskqltvGlppe.resvisaplpveeladliveavee.dnslgvLteevdvylgeliraqpllfsealllrig 447
                     ++++s  ++vG++++ +  ++s++++v+++ad +v++v+  +  +g+L+e++d+++g  i+a++l++s+a+ll++ 
      EEA23076.1 385 DVYSS--AAVGTYASgSTAFTSIISAVKTYADGYVSIVQGhAAANGSLSEQFDRNSGVEISARDLTWSYAALLTAN 458
                     *****..******************************************************************985 PP

>> CBM_20  Starch binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.2   0.0       1.4   8.4e+03      26      41 ..     169     184 ..     169     194 .. 0.74
   2 !  120.4   0.4   3.7e-39   2.2e-35       2      96 ..     540     634 ..     539     635 .. 0.97

  Alignments for each domain:
  == domain 1  score: -3.2 bits;  conditional E-value: 1.4
      CBM_20  26 eLGnWnpkkavklsas 41 
                 e GnW ++++++  a 
  EEA23076.1 169 EFGNWLIDNGYSSYAV 184
                 5799*99999887754 PP

  == domain 2  score: 120.4 bits;  conditional E-value: 3.7e-39
      CBM_20   2 vsVtFkvnattqlgesvyivGsiseLGnWnpkkavklsaseqtssyplWsttvslpagtkieYkyikkdsdgsvtWesgenrsltvpssgssttt 96 
                 v+VtF   att++ge+v+ivGsis+LG+W+++ka++lsas++tss+ lW++t+slpagt+++Ykyi+k+s+gs++Wes++nrs+tvps++ ++t+
  EEA23076.1 540 VAVTFDEIATTTYGENVFIVGSISQLGSWDTSKAIALSASQYTSSNHLWFATLSLPAGTTFQYKYIRKESNGSIVWESDPNRSYTVPSGCGVSTA 634
                 89*****99*********************************************************************************98875 PP

>> SAP130_C  Histone deacetylase complex subunit SAP130 C-terminus
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.8   5.9    0.0011       6.4      88     193 ..     476     580 ..     401     607 .. 0.69

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0011
    SAP130_C  88 alptsqhpaqaiptllaaaappsqpsavlsalpaavavtppvpaslanvvasptqpaasstaaaa..vssvvpeikikqeaeamdtskavpaltttsva 184
                 + p+s    +a  t  ++++ ++ ps+     ++ ++vt++  as+++++++++  ++++t +++  v+ +  ei      e++ +  ++ +l +  ++
  EEA23076.1 476 SVPSSCSMGSATGT-YSTPTATAWPSTLT--SATGIPVTTSATASVTKATSATSTTTSATTCTTPtsVAVTFDEIATTTYGENVFIVGSISQLGSWDTS 571
                 33555545555444.44455555565422..24557788877777776665555555555444440044455677777777777777766666666666 PP

    SAP130_C 185 paltslana 193
                  a++  a++
  EEA23076.1 572 KAIALSASQ 580
                 665555554 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (641 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       774  (0.0431703); expected 358.6 (0.02)
Passed bias filter:                      395  (0.0220313); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.63u 0.25s 00:00:00.88 Elapsed: 00:00:00.41
# Mc/sec: 4705.64
//
Query:       EEA23077.1  [L=173]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (173 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       397  (0.0221429); expected 358.6 (0.02)
Passed bias filter:                      365  (0.0203581); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.42u 0.26s 00:00:00.68 Elapsed: 00:00:00.42
# Mc/sec: 1241.84
//
Query:       EEA23078.1  [L=358]
Description: hypothetical protein PMAA_096730 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model     Description
    ------- ------ -----    ------- ------ -----   ---- --  --------  -----------
     0.0021   18.8   1.6      0.087   13.7   0.3    2.9  2  zf-C2H2_4  C2H2-type zinc finger
  ------ inclusion threshold ------
      0.015   15.3   0.0       0.05   13.6   0.0    1.9  1  zf-BED     BED zinc finger
      0.038   14.4   3.3       0.79   10.3   0.3    2.7  2  zf-C2H2    Zinc finger, C2H2 type


Domain annotation for each model (and alignments):
>> zf-C2H2_4  C2H2-type zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.7   0.3   1.5e-05     0.087       3      21 ..       8      26 ..       7      28 .. 0.93
   2 ?    3.0   0.1      0.04   2.4e+02       1      22 [.      58      81 ..      58      83 .. 0.91

  Alignments for each domain:
  == domain 1  score: 13.7 bits;  conditional E-value: 1.5e-05
   zf-C2H2_4  3 CpiCgksFsskkaLlrHlk 21
                C++C+k + +k++L+rHl 
  EEA23078.1  8 CRFCQKKYGNKTGLRRHLI 26
                *****************96 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.04
   zf-C2H2_4  1 fkCpi..CgksFsskkaLlrHlkt 22
                ++Cp   C++   +++++ +H+ t
  EEA23078.1 58 YQCPSrdCREIIATRQKFIQHVVT 81
                8999999**************976 PP

>> zf-BED  BED zinc finger
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.6   0.0   8.4e-06      0.05      18      40 ..       7      26 ..       2      33 .. 0.90

  Alignments for each domain:
  == domain 1  score: 13.6 bits;  conditional E-value: 8.4e-06
                EETTTTEE----SSTHHHHHHHH CS
      zf-BED 18 vCryCgkilsrgggttnLkrHLr 40
                vCr+C k++ ++   t+L+rHL 
  EEA23078.1  7 VCRFCQKKYGNK---TGLRRHLI 26
                8********999...******94 PP

>> zf-C2H2  Zinc finger, C2H2 type
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.3   0.3   0.00013      0.79       2      20 ..       7      25 ..       6      27 .. 0.94
   2 ?    4.2   0.2     0.011        68       1      21 [.      58      80 ..      58      84 .. 0.87

  Alignments for each domain:
  == domain 1  score: 10.3 bits;  conditional E-value: 0.00013
                EETTTTEEESSHHHHHHHH CS
     zf-C2H2  2 kCpdCgksFkrksnLkrHi 20
                +C  C k++ +k  L+rH+
  EEA23078.1  7 VCRFCQKKYGNKTGLRRHL 25
                6*****************8 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.011
                EEET..TTTEEESSHHHHHHHHH CS
     zf-C2H2  1 ykCp..dCgksFkrksnLkrHir 21
                y+Cp  dC +   ++  + +H  
  EEA23078.1 58 YQCPsrDCREIIATRQKFIQHVV 80
                9********99999999999975 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (358 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       410  (0.022868); expected 358.6 (0.02)
Passed bias filter:                      361  (0.020135); expected 358.6 (0.02)
Passed Vit filter:                        31  (0.00172904); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.50u 0.27s 00:00:00.77 Elapsed: 00:00:00.46
# Mc/sec: 2349.30
//
Query:       EEA23079.1  [L=164]
Description: MBL2-like secreted peptide, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
  ------ inclusion threshold ------
      0.071   13.3   0.3       0.15   12.3   0.3    1.5  1  Herpeto_peptide  Ribosomally synthesized peptide in Herpetosi
      0.077   11.1   0.2      0.081   11.0   0.2    1.0  1  DUF5525          Family of unknown function (DUF5525)


Domain annotation for each model (and alignments):
>> Herpeto_peptide  Ribosomally synthesized peptide in Herpetosiphon
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.3   1.7e-05      0.15      22      46 ..     138     158 ..     135     161 .. 0.88

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 1.7e-05
  Herpeto_peptide  22 eeaAelddvvGClvvegyprvGCdd 46 
                      ++ A l    GC+v + y+  GC  
       EEA23079.1 138 DWNADL----GCFVSGYYTSAGCSK 158
                      589999....*************75 PP

>> DUF5525  Family of unknown function (DUF5525)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.0   0.2     9e-06     0.081     704     758 ..      39      96 ..      14     143 .. 0.60

  Alignments for each domain:
  == domain 1  score: 11.0 bits;  conditional E-value: 9e-06
     DUF5525 704 vaspapasapapspapapapvag.pap..astaatvdsaeqhfaglhaslcdaisgsv 758
                 +   ++ +ap+p+pa a  p+a+ p    a + +++ s ++ f+   + +c+ i  s 
  EEA23079.1  39 ILPLTALAAPSPAPASAIDPAAAiPISdaAKSRIAALSDDEIFTKRNTEVCEIINVSS 96 
                 33334445666666665555443122122566778889999***********997653 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (164 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       523  (0.0291706); expected 358.6 (0.02)
Passed bias filter:                      392  (0.021864); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.41u 0.30s 00:00:00.71 Elapsed: 00:00:00.45
# Mc/sec: 1098.07
//
Query:       EEA23080.1  [L=220]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
  ------ inclusion threshold ------
      0.045   13.7   0.0       0.13   12.2   0.0    1.8  1  DUF1582   Protein of unknown function (DUF1582)


Domain annotation for each model (and alignments):
>> DUF1582  Protein of unknown function (DUF1582)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   7.4e-06      0.13      10      24 ..      77      91 ..      77      93 .. 0.93

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 7.4e-06
     DUF1582 10 LaaRSlavpSCvqeG 24
                +++R +++ +Cv+++
  EEA23080.1 77 VNCRNPSDKNCVGGV 91
                89***********98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (220 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       468  (0.026103); expected 358.6 (0.02)
Passed bias filter:                      225  (0.0125495); expected 358.6 (0.02)
Passed Vit filter:                        14  (0.000780858); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.42
# Mc/sec: 1587.65
//
Query:       EEA23081.1  [L=1652]
Description: phospholipid-transporting ATPase (DRS2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.9e-73  245.7  22.8    5.9e-73  245.7  22.8    2.4  2  PhoLip_ATPase_C  Phospholipid-translocating P-type ATPase C-t
      2e-24   85.1   2.0    7.1e-23   80.1   0.2    2.8  2  PhoLip_ATPase_N  Phospholipid-translocating ATPase N-terminal
    1.9e-12   48.0   0.9      2e-07   31.5   0.5    3.4  2  Hydrolase        haloacid dehalogenase-like hydrolase
    9.7e-12   44.8   0.1    9.7e-12   44.8   0.1    2.7  3  E1-E2_ATPase     E1-E2 ATPase
    1.7e-11   44.0   0.0    1.3e-10   41.2   0.0    2.3  2  Cation_ATPase    Cation transport ATPase (P-type)
  ------ inclusion threshold ------
      0.022   14.5   0.2      0.022   14.5   0.2    2.0  2  Hydrolase_3      haloacid dehalogenase-like hydrolase
       0.11   12.5   0.3       0.65   10.1   0.1    2.1  2  HAD_2            Haloacid dehalogenase-like hydrolase


Domain annotation for each model (and alignments):
>> PhoLip_ATPase_C  Phospholipid-translocating P-type ATPase C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   3.7      0.15   3.8e+02     153     235 ..     561     621 ..     530     640 .. 0.49
   2 !  245.7  22.8   2.3e-76   5.9e-73       1     249 []    1270    1524 ..    1270    1524 .. 0.97

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.15
  PhoLip_ATPase_C 153 fgtlvftalvlvvnlkvaletktwtliliililgsillyflflllyssllpsssefygvleelfsspsfwlvlllvvvvallp 235
                      + ++v+                      ++++ + +l+ ++++++ys    +++e  + l++++ s+   ++  l+++ +++p
       EEA23081.1 561 VVNYVV----------------------VLIVAIVLLMAMICTIAYSVWDDNYQEKAWYLTKAVVSIGPVFTSYLIMFNTMIP 621
                      333333......................3333333334444444444333333333333444444433333333333333333 PP

  == domain 2  score: 245.7 bits;  conditional E-value: 2.3e-76
  PhoLip_ATPase_C    1 vraSDyaiaqFrfLkrLLlvhGrwsyrRisklilyffyKnvvftlvqfwfqfyngfsgqslyeswlltlynllftslpvivlgifdqdvsae 92  
                       +r+SDy+iaqFrfL +LLlvhGrw+y+Ri+k+ l +f+K+++f+l q+++q yng++g+slye+w+l+++n+lftsl vi+lg++++d+sa 
       EEA23081.1 1270 ARISDYSIAQFRFLLKLLLVHGRWNYIRICKYTLGTFWKETLFYLSQALYQRYNGYTGTSLYENWSLSMFNTLFTSLAVIFLGVLEKDLSAP 1361
                       689***************************************************************************************** PP

  PhoLip_ATPase_C   93 lllkyPelYklgqknklfnlktfllwileglyqsliifflsylvlddssfsdgktndlqlfgtlvftalvlvvnlkval.etktwtliliil 183 
                       +ll++PelY++gq+n+ fn++ +l+w l ++++++i+f+ +y ++++s +  g +n+++ +g+l+fta+v+++n+k+++ e+++ t+++ i+
       EEA23081.1 1362 TLLAVPELYTKGQRNQGFNIRIYLGWALMAVIEAMIVFYTMYGLFGQSLI--GVDNTIFPMGLLTFTACVTIINFKLQFlEIHYKTIVSAIV 1451
                       **********************************************9987..*************************887************ PP

  PhoLip_ATPase_C  184 ilgsillyflflllyssllps.......ssefygvleelfsspsfwlvlllvvvvallpdllikvlkrtffps 249 
                       +++si+ +fl+++++s+ +         +    ++l+++ +s++fw+vl+l+v+ +ll++ ++ +++++ffp+
       EEA23081.1 1452 LFVSIGGWFLWNMILSARYNDatsgksiYDVRGNFLNRIGRSLNFWAVLFLIVASVLLFETTVTLFRQYFFPT 1524
                       *************999988879998887555556699**********************************97 PP

>> PhoLip_ATPase_N  Phospholipid-translocating ATPase N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   80.1   0.2   2.8e-26   7.1e-23      10      67 .]     289     346 ..     278     346 .. 0.93
   2 ?    3.5   0.1     0.023        59      17      36 ..    1294    1313 ..    1292    1320 .. 0.91

  Alignments for each domain:
  == domain 1  score: 80.1 bits;  conditional E-value: 2.8e-26
  PhoLip_ATPase_N  10 ekkkyasNkIsTsKYtlltFlpknLfeqFrrvaNlYFLviailqliPqisplspvtti 67 
                      + ++y++N+I++s+Y+l++F+pk+++ qF++vaN+YFLv++ilq+iP++s+++++tti
       EEA23081.1 289 SGSSYVDNSIRSSRYSLWSFFPKQFLAQFSKVANFYFLVVSILQMIPGLSTTGTFTTI 346
                      3469****************************************************97 PP

  == domain 2  score: 3.5 bits;  conditional E-value: 0.023
  PhoLip_ATPase_N   17 NkIsTsKYtlltFlpknLfe 36  
                       N+I+  KYtl tF    Lf+
       EEA23081.1 1294 NYIRICKYTLGTFWKETLFY 1313
                       9************9999985 PP

>> Hydrolase  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    5.8   0.0    0.0057        15       4      26 ..     670     692 ..     667     751 .. 0.84
   2 !   31.5   0.5   7.7e-11     2e-07      59     209 ..    1065    1255 ..    1019    1256 .. 0.80

  Alignments for each domain:
  == domain 1  score: 5.8 bits;  conditional E-value: 0.0057
                 EEEESBTTTBCHHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase   4 vvfDkdGTLttgepsvedvivsa 26 
                 ++ Dk+GTLt+ ++  +  +v  
  EEA23081.1 670 IFSDKTGTLTNNTMKFRMMTVAG 692
                 889********998877766655 PP

  == domain 2  score: 31.5 bits;  conditional E-value: 7.7e-11
                  HHHHETTTEHHHHTHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHHTTHHHHHHHHHHTHHBHTTHHHHHHHHHHTTEEEEEEESSEHHHHHHHHHHT CS
                  xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
   Hydrolase   59 gfatfigrgayaigkpewltaldippdlgaaigsaqsqgrtvallqaralavftiadplkvkpeaaeavasLkaagievvlltgdnpetaeraanql 155 
                  ++ +     ay++ +  +++++       ++i++  +q +t    q ++++  +i+d+  + +++ ea+ +L++a+i++++ltgd +eta  + + +
  EEA23081.1 1065 EWKR-----AYQEASTSLVDRQ-------EKIEKVGEQIET----QLELVGATAIEDK--LQKGVPEAIDKLRRANIKLWMLTGDKRETAINIGHSC 1143
                  3333.....4444444444444.......444444444444....5577*********..************************************9 PP

                  T..GGGESEEEEHHCES.STTT.....................................................SHHHHHHHHHHHT....STGGG CS
                  x..xxxxxxxxxxxxxx.xxxx.....................................................xxxxxxxxxxxxx....xxxxx RF
   Hydrolase  156 G..ddyfdaviasdiet.vakp.....................................................spegkvaaireLq....gkpee 192 
                     ++y +++i   +++ v k                                                      sp++k  +++  +       + 
  EEA23081.1 1144 RlvKEYSEVIILDHEVGnVEKTivstissirkgrmahsvlvvdgqtlsmierdetlmprffklailvdsviccraSPKQKAFLVKSVRkhvlN--AI 1238
                  998777766666555556666677888888999999999************************************************867433..45 PP

                  EEEEESSHHHHHHHHHT CS
                  xxxxxxxxxxxxxxxxx RF
   Hydrolase  193 vamVGDgvnDaaalaaA 209 
                  ++++GDg+nD+a++++A
  EEA23081.1 1239 TLAIGDGANDIAMIQEA 1255
                  *************9998 PP

>> E1-E2_ATPase  E1-E2 ATPase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.2   1.0       4.2   1.1e+04     117     156 ..     312     351 ..     311     353 .. 0.77
   2 !   44.8   0.1   3.8e-15   9.7e-12      11     169 ..     404     630 ..     393     637 .. 0.90
   3 ?   -1.8   0.1      0.72   1.9e+03      89     116 ..     892     919 ..     890     920 .. 0.91

  Alignments for each domain:
  == domain 1  score: -4.2 bits;  conditional E-value: 4.2
                   HHHHHHHHHHHHHHHHHHHS-STTTSSTTHHHHHHHHHHH CS
  E1-E2_ATPase 117 klgkvlvpvvlliallvflialllgkslaeallralallv 156
                   ++ +++++v+ + +l+v +++++ g s++ +++ ++ ll+
    EEA23081.1 312 QFLAQFSKVANFYFLVVSILQMIPGLSTTGTFTTIVPLLI 351
                   5778888999999999999988888888877777776665 PP

  == domain 2  score: 44.8 bits;  conditional E-value: 3.8e-15
                   -TTS-EEEEGGG--TTSEEEEETT-B--SEEEEEE.....E-SEEE-TTTS---S-EE-...................................... CS
  E1-E2_ATPase  11 rdgteeeidakelvpGDivllkagdrvpaDgrive.....gsaevdesaLTGEslpvek...................................... 64 
                    dg ++ ++ +++++GD+++l+ ++ vpaD+++++     g a +++ aL GE    +k                                      
    EEA23081.1 404 DDGDWVAVKWRDVRVGDVIQLRRNQPVPADVVLLHadgpnGVAHIETMALDGETNLKTKqpchpvakacqtpediiarknlirftvedpnidlykfd 500
                   799********************************88877777****************************************************** PP

                   ............G-TTEE-TT-EEEE.-EEEEEEEE-TTTSTTTTTSTTS--------HHHHHHHHHHHHHHHHHHHHHHHHHHS-STTTSSTT... CS
  E1-E2_ATPase  65 ............ekgdmvfsGtvvvs.geakavVtatgedtelgkiarlveeakskktplqkkldklgkvlvpvvlliallvflialllgksla... 145
                               ++++ ++ G++  +  ++ a V+ tge+ ++    ++ ++++ kk+ lq  ++ ++  +v++vll+a+++ ++  ++ ++ +   
    EEA23081.1 501 gnvtvndeklpiTNNEILYRGSILRNtERIYAMVIYTGEECKIRM--NANKNPRIKKPALQTVVNYVVVLIVAIVLLMAMICTIAYSVWDDNYQeka 595
                   *********9999***********99778999*******999885..55578888*********************************999999888 PP

                   ...........HHHHHHHHHHHHHS-TTHHHHHHH CS
  E1-E2_ATPase 146 ...........eallralallvaaiPcaLplavpl 169
                                +++ l ++  +iP+ L + + +
    EEA23081.1 596 wyltkavvsigPVFTSYLIMFNTMIPISLYVSMEI 630
                   88888888877777778888888888888777665 PP

  == domain 3  score: -1.8 bits;  conditional E-value: 0.72
                   TTTSTTTTTSTTS--------HHHHHHH CS
  E1-E2_ATPase  89 gedtelgkiarlveeakskktplqkkld 116
                   g d+++ k+ r+++ a++k  ++q+ ++
    EEA23081.1 892 GADSTITKLLRQASLAQQKAVQIQRRAS 919
                   789*********************9875 PP

>> Cation_ATPase  Cation transport ATPase (P-type)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.2   0.0     5e-14   1.3e-10       2      86 ..     797     899 ..     796     903 .. 0.79
   2 ?   -1.4   0.0      0.97   2.5e+03      12      28 ..    1121    1137 ..    1076    1146 .. 0.89

  Alignments for each domain:
  == domain 1  score: 41.2 bits;  conditional E-value: 5e-14
  Cation_ATPase   2 lcNsaafsensekdevkllGnktEsALlvlaekl...................gldteelreetkkvqeipFnssrKrmsvvlklepekkvrlyvK 78 
                    lc+ +  ++++  + +    +++E AL+ +a++l                   g + + ++e ++ + +i+F+s rKrmsv+++  p+++++l++K
     EEA23081.1 797 LCHTCIPERDEAGNITYQATSPDELALVTAAQQLgylfmdrqqntltvrtypsGHEDDPWDEVYEVLDVIEFTSARKRMSVIVRM-PDQRICLFCK 891
                    677777777777788888999*************55555555555555555555555555555*********************9.8********* PP

  Cation_ATPase  79 GApeiilk 86 
                    GA   i+k
     EEA23081.1 892 GADSTITK 899
                    ***99987 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 0.97
  Cation_ATPase   12 sekdevkllGnktEsAL 28  
                     ++ + + l+G+k E+A+
     EEA23081.1 1121 ANIKLWMLTGDKRETAI 1137
                     56677899******997 PP

>> Hydrolase_3  haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.5   0.2   8.5e-06     0.022     203     226 ..    1236    1259 ..    1109    1264 .. 0.84
   2 ?   -3.7   0.3       3.1   7.9e+03      82     129 ..    1559    1605 ..    1557    1616 .. 0.69

  Alignments for each domain:
  == domain 1  score: 14.5 bits;  conditional E-value: 8.5e-06
                   GGGEEEEESSGGGHHHHHHSSEEE CS
  Hydrolase_3  203 leeviafGDgeNDieMLeaaglgv 226 
                   ++ ++a+GDg NDi+M++ a +g+
   EEA23081.1 1236 NAITLAIGDGANDIAMIQEAHVGI 1259
                   55699**************98887 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 3.1
                   HHHHHHHHHHHHTTCEEEEEESSEEEESTT.THHHHHHHHHCHCTCEE CS
  Hydrolase_3   82 edvkeiikllkennveillytedkvyvlnkeksekkkkeeektkkkke 129 
                   +++++ +++++e++ +++ ++e + y +++ ++e++  ++++++++++
   EEA23081.1 1559 SKIQSSLEIAREEEEQLAREREVNEYLNRP-RNEDDAAHHHHHHHNSQ 1605
                   677888899999999999999999999999.55555555555544443 PP

>> HAD_2  Haloacid dehalogenase-like hydrolase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.1   0.1   0.00025      0.65      35     134 ..    1064    1162 ..    1031    1185 .. 0.78
   2 ?   -1.0   0.0      0.61   1.6e+03     141     172 ..    1225    1256 ..    1202    1259 .. 0.73

  Alignments for each domain:
  == domain 1  score: 10.1 bits;  conditional E-value: 0.00025
       HAD_2   35 eelrkliglslrellrklgeseeeeekieellrkyneekkkkevkpydgvkelLeeLkeagyklgivTsksreaveekleqlgi.esyFdvivtsed 130 
                   e ++ +   +  l+++ ++ e++ e ie+ l+ + +   +   k+ +gv e++++L++a++kl   T  +re++ +    + + ++y +vi+  ++
  EEA23081.1 1064 TEWKRAYQEASTSLVDRQEKIEKVGEQIETQLELVGATAIE--DKLQKGVPEAIDKLRRANIKLWMLTGDKRETAINIGHSCRLvKEYSEVIILDHE 1158
                  55555555555566666666666666777777777776666..68889**************************99999988862688888888888 PP

       HAD_2  131 vekk 134 
                  v++ 
  EEA23081.1 1159 VGNV 1162
                  8765 PP

  == domain 2  score: -1.0 bits;  conditional E-value: 0.61
       HAD_2  141 iekaleklklkkeeviyvGDsptDieaakkag 172 
                  ++    + ++ ++ ++ +GD  +Di   ++a 
  EEA23081.1 1225 FLVKSVRKHVLNAITLAIGDGANDIAMIQEAH 1256
                  4444446688888999*********9988876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (1652 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1310  (0.073066); expected 358.6 (0.02)
Passed bias filter:                      683  (0.0380947); expected 358.6 (0.02)
Passed Vit filter:                        68  (0.00379274); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 1.05u 0.32s 00:00:01.37 Elapsed: 00:00:00.48
# Mc/sec: 10337.31
//
Query:       EEA23082.1  [L=532]
Description: transcription factor RfeF, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (532 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       490  (0.02733); expected 358.6 (0.02)
Passed bias filter:                      346  (0.0192983); expected 358.6 (0.02)
Passed Vit filter:                        42  (0.00234257); expected 17.9 (0.001)
Passed Fwd filter:                         8  (0.000446204); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.61u 0.28s 00:00:00.89 Elapsed: 00:00:00.43
# Mc/sec: 3730.16
//
Query:       EEA23083.1  [L=649]
Description: signal recognition particle protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    1.5e-21   76.5   2.2    4.1e-21   75.2   2.2    1.8  1  SRP_TPR_like  Putative TPR-like repeat
    4.2e-17   62.3   9.3    4.2e-17   62.3   9.3    2.5  2  SRP72         SRP72 RNA-binding domain
    6.9e-06   26.5  13.3       0.08   13.5   0.0    5.9  7  TPR_19        Tetratricopeptide repeat
  ------ inclusion threshold ------
      0.052   13.8   5.0        5.7    7.2   3.7    3.9  5  ANAPC3        Anaphase-promoting complex, cyclosome, subunit 
       0.24   11.8   8.0        6.9    7.1   0.1    4.0  4  BTAD          Bacterial transcriptional activator domain
       0.86    9.8   5.4        8.5    6.7   0.0    4.2  5  TPR_7         Tetratricopeptide repeat
        3.4    8.0  11.7         54    4.2   2.0    5.2  7  TPR_2         Tetratricopeptide repeat


Domain annotation for each model (and alignments):
>> SRP_TPR_like  Putative TPR-like repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   75.2   2.2   1.6e-24   4.1e-21       2     116 ..      17     149 ..      16     150 .. 0.92

  Alignments for each domain:
  == domain 1  score: 75.2 bits;  conditional E-value: 1.6e-24
  SRP_TPR_like   2 neeyekilrlegkelkkf.........kvvaliklekyeeaLkllkkgs.alsedvrfEkaYvlYklkkykkalkilkkveaeekvkvlksqvlYrl 88 
                    e++++il++++++lkk+         kvvalikl++y+++L++ ++++ al e+  +E aY+lYk  ++++a+++  k  +  ++k++++q  Yr+
    EEA23083.1  17 IEDHDEILKASNEVLKKSktdiqaqhsKVVALIKLDRYDDTLRVFEDAGdALKEKAAVEYAYALYKCGRLREAAEVAAKSAGGRGAKHVEAQASYRA 113
                   589****************************************99986549****************************99999************* PP

  SRP_TPR_like  89 gsyekA...YklL.....skekkedelvvNllAvds 116
                   +++++A   Y+ L        ++ ++l++N+ A d+
    EEA23083.1 114 ENFANAatiYESLlgeeeELGNEYNDLRINTWATDA 149
                   *****999999998877545566799*******998 PP

>> SRP72  SRP72 RNA-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.3   9.3   1.6e-20   4.2e-17      13      58 .]     560     605 ..     553     605 .. 0.86
   2 ?   -1.3   1.5       1.2   3.1e+03      15      31 ..     634     648 ..     622     649 .] 0.38

  Alignments for each domain:
  == domain 1  score: 62.3 bits;  conditional E-value: 1.6e-20
       SRP72  13 tsekgkkkkrkkkrkRkvklPKnydpgvtpDPERWLPrreRSsYrk 58 
                 + +k++++ r+kkr Rk++lPK+yd++++pDPERWLP+r+RSsYr+
  EEA23083.1 560 AATKEQQNARAKKRIRKSRLPKDYDASKKPDPERWLPLRDRSSYRP 605
                 3344455568***********************************7 PP

  == domain 2  score: -1.3 bits;  conditional E-value: 1.2
       SRP72  15 ekgkkkkrkkkrkRkvk 31 
                  +++ +  +  +k+k+k
  EEA23083.1 634 AATAGT--TSAKKKKGK 648
                 222222..333444433 PP

>> TPR_19  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.4   0.1     0.043   1.1e+02       6      55 ..      19      68 ..      18      74 .. 0.87
   2 !    7.8   1.8    0.0019       4.8       3      48 ..      50      93 ..      48      97 .. 0.86
   3 ?    1.2   0.0      0.21   5.4e+02       3      21 ..     112     130 ..     110     143 .. 0.79
   4 ?   -2.2   0.0       2.5   6.3e+03      35      52 ..     183     200 ..     174     213 .. 0.68
   5 !    6.1   0.0     0.006        15      35      54 ..     229     248 ..     225     252 .. 0.89
   6 !   13.5   0.0   3.1e-05      0.08       7      54 ..     354     401 ..     351     410 .. 0.91
   7 ?   -1.5   0.1       1.5   3.8e+03       8      35 ..     462     486 ..     461     494 .. 0.76

  Alignments for each domain:
  == domain 1  score: 3.4 bits;  conditional E-value: 0.043
      TPR_19  6 dyaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpeed 55
                d++e l++  ++l+++  +  a+   + al++l ++d+  ++ ++++++ 
  EEA23083.1 19 DHDEILKASNEVLKKSKTDIQAQHSKVVALIKLDRYDDTLRVFEDAGDAL 68
                89999999999*************9************9888888777765 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.0019
      TPR_19  3 aegdyaeAlalleqalqedpknaearllLAeallalgqldeAealL 48
                +  +y++ l+ +e a ++  + a++ +  A al++ g+l eA ++ 
  EEA23083.1 50 KLDRYDDTLRVFEDAGDALKEKAAVEY--AYALYKCGRLREAAEVA 93
                567899********9988888888888..*************9875 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.21
      TPR_19   3 aegdyaeAlalleqalqed 21 
                  ++++a+A+ ++e++l e+
  EEA23083.1 112 RAENFANAATIYESLLGEE 130
                 5789**********99775 PP

  == domain 4  score: -2.2 bits;  conditional E-value: 2.5
      TPR_19  35 llalgqldeAealLdalp 52 
                  la g+l++ e lL+++ 
  EEA23083.1 183 SLARGDLKQGEILLKRAK 200
                 566666666666666654 PP

  == domain 5  score: 6.1 bits;  conditional E-value: 0.006
      TPR_19  35 llalgqldeAealLdalpee 54 
                 l+++g++++Ae++++++ ++
  EEA23083.1 229 LVSQGRVEDAEEIVKEISLD 248
                 889************99876 PP

  == domain 6  score: 13.5 bits;  conditional E-value: 3.1e-05
      TPR_19   7 yaeAlalleqalqedpknaearllLAeallalgqldeAealLdalpee 54 
                 +  A++ l+++l+  pk+  + l  ++++   g+++ A+++L+  +++
  EEA23083.1 354 HPKAIQDLRSLLDRRPKDIGLVLTIVQLYAGVGNTTSAINVLESSLRA 401
                 5689**************************************988776 PP

  == domain 7  score: -1.5 bits;  conditional E-value: 1.5
      TPR_19   8 aeAlalleqalqedpknaearllLAeal 35 
                 a+A++ll +    dp ++++   L   l
  EEA23083.1 462 AAAASLLHSS---DPADLAISQELFSTL 486
                 6899999999...999999887776555 PP

>> ANAPC3  Anaphase-promoting complex, cyclosome, subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.4   0.0      0.07   1.8e+02      54      81 ..      36      63 ..      18      64 .. 0.73
   2 ?    7.2   3.7    0.0022       5.7      23      80 ..      70     124 ..      64     126 .. 0.90
   3 ?    1.2   0.1      0.17   4.4e+02      28      50 ..     105     128 ..     100     133 .. 0.81
   4 ?   -1.9   0.0       1.6   4.2e+03      52      52 ..     210     210 ..     170     245 .. 0.54
   5 ?   -1.6   0.0       1.3   3.3e+03      30      80 ..     345     396 ..     324     398 .. 0.70

  Alignments for each domain:
  == domain 1  score: 2.4 bits;  conditional E-value: 0.07
                C-HHHHHHHHHHHHHTT-HHHHHHHH-S CS
      ANAPC3 54 kslgcrylfAqcllkLkkyeeAiaaLek 81
                +++++   +  +l+kL++y++ ++++e 
  EEA23083.1 36 TDIQAQHSKVVALIKLDRYDDTLRVFED 63
                45555555667899*********99986 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0022
                 HHHHHHHHHHHHHTT-HHHHHHHHHCTSHHHC-HHHHHHHHHHHHHTT-HHHHHHHH- CS
      ANAPC3  23 pedayllAlclylngqykrAyellrkaklnskslgcrylfAqcllkLkkyeeAiaaLe 80 
                 +++a  +A++ly+ g+  +A e++ k+       g+  + Aq+++  +++  A +++e
  EEA23083.1  70 EKAAVEYAYALYKCGRLREAAEVAAKS---AGGRGAKHVEAQASYRAENFANAATIYE 124
                 789999*********************...8888999999999999999999999887 PP

  == domain 3  score: 1.2 bits;  conditional E-value: 0.17
                 HHHHHHHHTT-HHHHHHHHHCT.S CS
      ANAPC3  28 llAlclylngqykrAyellrka.k 50 
                   A++ y+++++  A ++++++ +
  EEA23083.1 105 VEAQASYRAENFANAATIYESLlG 128
                 569999*********999998844 PP

  == domain 4  score: -1.9 bits;  conditional E-value: 1.6
                 H CS
      ANAPC3  52 n 52 
                  
  EEA23083.1 210 S 210
                 2 PP

  == domain 5  score: -1.6 bits;  conditional E-value: 1.3
                 HHHHHHTT-HHHHHHHHHCT.SHHHC-HHHHHHHHHHHHHTT-HHHHHHHH- CS
      ANAPC3  30 AlclylngqykrAyellrka.klnskslgcrylfAqcllkLkkyeeAiaaLe 80 
                 A +  + + + +A++ lr++ + ++k++g  +++ q +   ++   Ai++Le
  EEA23083.1 345 AAARVRGETHPKAIQDLRSLlDRRPKDIGLVLTIVQLYAGVGNTTSAINVLE 396
                 5555555667788888888888888888888888888888888888888887 PP

>> BTAD  Bacterial transcriptional activator domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.1    0.0027       6.9      63     133 ..       6      75 ..       2      85 .. 0.87
   2 ?   -1.2   0.1      0.97   2.5e+03       2      30 ..     169     197 ..     146     217 .. 0.75
   3 ?    7.0   0.0    0.0029       7.3      53     130 ..     331     406 ..     294     413 .. 0.78
   4 ?   -3.7   0.0       5.8   1.5e+04      21      39 ..     432     450 ..     429     466 .. 0.72

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0027
                 HHHHHHHHHHHHTT-HHHHHHHHHHHHHHSTT-HHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHHHS-- CS
        BTAD  63 ealealaeaelrlGraeealaelealvaehPlrErlhrqlmrAlarsGrqaeALevYerlrrlLaeeLgve 133
                 + l++l++ ++++++++e+l+  ++ +++  ++ ++      Al +++r  + L+v+e++ + L+e   ve
  EEA23083.1   6 QSLRTLLQ-HSTIEDHDEILKASNEVLKKSKTDIQAQHSKVVALIKLDRYDDTLRVFEDAGDALKEKAAVE 75 
                 55666776.78999**************************************************9986666 PP

  == domain 2  score: -1.2 bits;  conditional E-value: 0.97
                 HHHHHHHHHHHHHHHHHTT-HHHHHHHHH CS
        BTAD   2 Dlarfealvaagraalaagdpeeaaelle 30 
                 Dl+ fe  ++a+ a+la+gd ++   ll+
  EEA23083.1 169 DLESFETSYNAACASLARGDLKQGEILLK 197
                 67777777777777777777665544444 PP

  == domain 3  score: 7.0 bits;  conditional E-value: 0.0029
                 HHHHHHHHHHHHHHHHHHHHHHTT-HHHHHHHHHHHHHHSTT-HHHHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHHH CS
        BTAD  53 ererleelrlealealaeaelrlGraeealaelealvaehPlrErlhrqlmrAlarsGrqaeALevYerlrrlLaeeL 130
                   ++ ++  l+++ a a+  +r + + +a+++l++l++  P +  l+  + + +a +G++  A++v e+  r L+e +
  EEA23083.1 331 PSTEPHDNLLSIYNAAAR--VRGETHPKAIQDLRSLLDRRPKDIGLVLTIVQLYAGVGNTTSAINVLESSLRALEESI 406
                 555666777777776666..89999*******************************************9999999876 PP

  == domain 4  score: -3.7 bits;  conditional E-value: 5.8
                 -HHHHHHHHHHHHTT--SS CS
        BTAD  21 dpeeaaelleaAlalwrGp 39 
                 ++ +  ++l +A+++wr +
  EEA23083.1 432 RKSHIKAELGKAASFWRQQ 450
                 5555667788888888865 PP

>> TPR_7  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.1         7   1.8e+04      11      21 ..      82      92 ..      78      96 .. 0.78
   2 ?    2.3   0.2      0.08   2.1e+02      11      30 ..     112     131 ..     107     137 .. 0.74
   3 ?   -3.7   0.1         7   1.8e+04       7      14 ..     151     158 ..     150     160 .. 0.84
   4 ?   -1.0   0.0      0.95   2.4e+03       9      22 ..     229     242 ..     227     251 .. 0.82
   5 ?    6.7   0.0    0.0033       8.5       7      34 ..     380     408 ..     376     410 .. 0.88

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 7
       TPR_7 11 rlGdyeeAiel 21
                ++G+ +eA+e+
  EEA23083.1 82 KCGRLREAAEV 92
                67888999885 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.08
       TPR_7  11 rlGdyeeAielyeqsLaltk 30 
                 r  ++++A+++ye +L+ ++
  EEA23083.1 112 RAENFANAATIYESLLGEEE 131
                 56799********9775444 PP

  == domain 3  score: -3.7 bits;  conditional E-value: 7
       TPR_7   7 rlysrlGd 14 
                 rl++r+Gd
  EEA23083.1 151 RLWQREGD 158
                 79999999 PP

  == domain 4  score: -1.0 bits;  conditional E-value: 0.95
       TPR_7   9 ysrlGdyeeAiely 22 
                  +++G+ e+A+e+ 
  EEA23083.1 229 LVSQGRVEDAEEIV 242
                 6799******9975 PP

  == domain 5  score: 6.7 bits;  conditional E-value: 0.0033
       TPR_7   7 rlysrlGdyeeAielyeqsL.altkdped 34 
                 +ly  +G++  Ai ++e sL al+++ ++
  EEA23083.1 380 QLYAGVGNTTSAINVLESSLrALEESISE 408
                 789999*****************998765 PP

>> TPR_2  Tetratricopeptide repeat
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.4   0.0       2.9   7.5e+03      10      25 ..      47      62 ..      46      64 .. 0.73
   2 ?    4.2   2.0     0.021        54       6      26 ..      75      95 ..      71      97 .. 0.84
   3 ?    1.4   0.3      0.17   4.4e+02       7      25 ..     106     124 ..     102     127 .. 0.85
   4 ?    4.2   0.1     0.023        58       4      33 ..     176     205 ..     173     206 .. 0.90
   5 ?   -3.4   0.0       5.8   1.5e+04      13      22 ..     231     240 ..     228     242 .. 0.84
   6 ?   -2.4   0.0       2.8   7.2e+03      15      32 ..     312     329 ..     309     330 .. 0.83
   7 ?   -3.7   0.0         7   1.8e+04      19      34 .]     356     371 ..     355     371 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.4 bits;  conditional E-value: 2.9
       TPR_2 10 ayyklgdyeeAleafe 25
                a++kl++y++ l+ fe
  EEA23083.1 47 ALIKLDRYDDTLRVFE 62
                78999***98555555 PP

  == domain 2  score: 4.2 bits;  conditional E-value: 0.021
       TPR_2  6 nlGlayyklgdyeeAleafek 26
                + ++a+yk g++ eA+e   k
  EEA23083.1 75 EYAYALYKCGRLREAAEVAAK 95
                689************997655 PP

  == domain 3  score: 1.4 bits;  conditional E-value: 0.17
       TPR_2   7 lGlayyklgdyeeAleafe 25 
                  ++a y++ +++ A+  +e
  EEA23083.1 106 EAQASYRAENFANAATIYE 124
                 6899**********99998 PP

  == domain 4  score: 4.2 bits;  conditional E-value: 0.023
       TPR_2   4 lynlGlayyklgdyeeAleafekAleldPn 33 
                  yn ++a +++gd+++ + ++++A el+ +
  EEA23083.1 176 SYNAACASLARGDLKQGEILLKRAKELCKT 205
                 5999*********************99876 PP

  == domain 5  score: -3.4 bits;  conditional E-value: 5.8
       TPR_2  13 klgdyeeAle 22 
                  +g+ e+A+e
  EEA23083.1 231 SQGRVEDAEE 240
                 69*****986 PP

  == domain 6  score: -2.4 bits;  conditional E-value: 2.8
       TPR_2  15 gdyeeAleafekAleldP 32 
                 ++y+  ++   kAl+  P
  EEA23083.1 312 QKYDGVIRSTTKALAQRP 329
                 68899999999***9877 PP

  == domain 7  score: -3.7 bits;  conditional E-value: 7
       TPR_2  19 eAleafekAleldPnn 34 
                 +A+++++  l   P++
  EEA23083.1 356 KAIQDLRSLLDRRPKD 371
                 8999999999988875 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (649 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1061  (0.0591779); expected 358.6 (0.02)
Passed bias filter:                      513  (0.0286129); expected 358.6 (0.02)
Passed Vit filter:                        35  (0.00195214); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               7  [number of targets reported over threshold]
# CPU time: 0.66u 0.32s 00:00:00.98 Elapsed: 00:00:00.47
# Mc/sec: 4126.92
//
Query:       EEA23084.1  [L=283]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    6.4e-11   42.2   0.0    7.8e-11   41.9   0.0    1.1  1  DLH            Dienelactone hydrolase family
  ------ inclusion threshold ------
       0.12   11.8   0.0       0.18   11.3   0.0    1.3  1  Dioxygenase_C  Dioxygenase


Domain annotation for each model (and alignments):
>> DLH  Dienelactone hydrolase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.9   0.0   8.7e-15   7.8e-11       2     205 ..      66     268 ..      65     283 .] 0.74

  Alignments for each domain:
  == domain 1  score: 41.9 bits;  conditional E-value: 8.7e-15
         DLH   2 daylatpknakkpvvvviqeifGvndnikdiserl.aeeGYvalaPdlYarqa....ldpndeaeaaraldelvskva.eekvlddlkaavaylksvpe 94 
                 d+y+a+ +++ k + vvi +ifG   +  + ++ l a+ G v ++Pd++  ++      p d++e++ a+++ ++++a    vl ++ka +a +k +  
  EEA23084.1  66 DTYVAGNTSS-KTGLVVIYDIFGFYTQTLQGADLLaAQTGAVTFVPDVLENEYalhsWLPPDTEEKRIAFEGFFKDTAaPPLVLPKVKAWLAEAKGKY- 162
                 7999999999.99***********966666666662678************999999557788888888888888774167899********999987. PP

         DLH  95 vstkkvgvvGfCmGGalalllaaevpevdaavafYGlspekeleeaakikapilalfgeeDefipadevekleealkaanvdlelkvYpgagHaFands 193
                  s +k g+ G C+GG++a+l ++e+  ++ +   ++      l + a++k  ++ ++  + +    d + + + a+ ++     ++ Y+   H+ + ++
  EEA23084.1 163 PSIEKWGILGVCWGGKIAILNSTEGSDFAVSGQVHP-----GLYDGADAKNAVIPHVVLASKEESTDVTAEYKAAFDKSTLGSYVDTYATMHHGWMGAR 256
                 677**********************75666666666.....4444444444443333222222233333568899999999999999999999999988 PP

         DLH 194 resyneeaaeda 205
                 ++ +++e +++ 
  EEA23084.1 257 ANLEDPENKKEY 268
                 885555554443 PP

>> Dioxygenase_C  Dioxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0     2e-05      0.18      24      65 ..     126     167 ..     108     210 .. 0.79

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 2e-05
                    -TT--EEEEEEEEE-TTSSB-TT-EEEEE---TTS--TTS-T CS
  Dioxygenase_C  24 eeegerlvlsGrvldeaGkplagalvelWhanaeGrYshkke 65 
                    + e +r+ ++G   d+a  pl+  +v  W a+a+G Y   ++
     EEA23084.1 126 DTEEKRIAFEGFFKDTAAPPLVLPKVKAWLAEAKGKYPSIEK 167
                    667899*******************************87665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (283 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       333  (0.0185733); expected 358.6 (0.02)
Passed bias filter:                      285  (0.015896); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.28s 00:00:00.74 Elapsed: 00:00:00.45
# Mc/sec: 1882.63
//
Query:       EEA23085.1  [L=445]
Description: aspartic-type endopeptidase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    2.1e-53  181.8   4.9    2.6e-53  181.5   4.9    1.1  1  Asp              Eukaryotic aspartyl protease
    3.1e-05   24.3   1.1    0.00011   22.5   1.1    2.0  1  TAXi_N           Xylanase inhibitor N-terminal
    0.00017   22.2   1.1        1.6    9.4   0.1    3.6  3  Asp_protease_2   Aspartyl protease
    0.00047   20.0   0.8       0.11   12.2   0.2    3.1  2  TAXi_C           Xylanase inhibitor C-terminal
     0.0031   18.0   0.1       0.22   12.1   0.0    2.8  2  gag-asp_proteas  gag-polyprotein putative aspartyl protease


Domain annotation for each model (and alignments):
>> Asp  Eukaryotic aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  181.5   4.9   7.1e-57   2.6e-53       2     314 ..     100     435 ..      99     436 .. 0.88

  Alignments for each domain:
  == domain 1  score: 181.5 bits;  conditional E-value: 7.1e-57
                 EEEEEEETTTTEEEEEEEETT--SEEEEBTT..........ESTSHC....HHTSS-B-GGG-TT-E.EEEEEEEEECTTS.EEEEEEEEEEEEETTEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..........xxxxxx....xxxxxxxxxxxxxxxx.xxxxxxxxxxxxx.xxxxxxxxxxxxxxxxx RF
         Asp   2 YfgeisiGtpeqkftvifDTGSsdlWVpssk..........ckkssa....ckshstydpskSstyk.kngkslsisYGdg.svsGflsqdtvkvgglt 84 
                 +++ei+iGt  q+f+vi+DTGSsd+WV++s                +    c++ + y+ +k+  +k +++++++i YGdg  ++G+++++ v+++g++
  EEA23085.1 100 FATEIKIGT--QTFEVILDTGSSDTWVVESGfkcvdvstkkN----EsesyCNFGTPYKVEKT--FKtNKNERFKIGYGDGeFLTGIMGTEAVTMAGIK 190
                 789*****9..6******************999888864432....22344999999988874..44377899************************** PP

                 EEEEEEEEEEEESSHHHTTSSSSEEEE-S-GGGSCGG........SCCHHHHHHHTTSSSSSEEEEEE-S.TTSSEEEEEESSEEGGGEEEEEEEEEES CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx........xxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp  85 vknqefgeatkepgstflaakfdGiLGlgfkeisvee........atpvfdnlvsqglikepvfsvylnr.eeeeggeivfGgvDeskykGsltyvpvt 174
                 v++q++++a+ +      + +++G+ G +++++++           +p f +++++gl+++  fs+ + r  +  +g +++Gg+ +  +  +++++p+ 
  EEA23085.1 191 VEHQTIALANYAGW--YGDGTTSGLAGFAYPALTSAFssngtqkvYNPLFTTMYKEGLVDS-YFSLAILRdVSGPSGYLTLGGLPPIDFDETFATTPIL 286
                 *********99877..68899********98887654455555555566888*******97.699988885677899********************87 PP

                 S.......TSS..TEEEEEEEEETTEEEEEEEEEEEEEETTCSSEEEEHHHHHHHHHHHT..TEEEETTCEEEEETTGGGGSEEEEEEETTEEEEEEGG CS
                 x.......xxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp 175 s.......kgy..wqielesvtvggktvlcssgcqailDtGTsllalptsivekiakaig..akksesegeyvvdCdslsslpdisftiggakitvpvs 262
                         kgy  ++ie+++++++gk++++ sg + i+D+GT+l + pts++++++ a++  a ++ ++g yvvdC++  + p  s+tigg+++ v++ 
  EEA23085.1 287 VtsisgysKGYdfYTIEVDNINLNGKALSSVSGARYIVDSGTTLNYYPTSMANAVNAAFSppAVYNATQGAYVVDCKA--TAPAHSITIGGKEFIVNPL 383
                 7779888866566*********************************************98334566779********8..99***************** PP

                 GGEEEESSSTTSEEEESE...EECCTSSSEEEEHHHHTTEEEEEETTTTEEEEEE CS
                 xxxxxxxxxxxxxxxxxx...xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
         Asp 263 elvlkeeeseesqCilgl...vseeegdlwiLGdvFlrsayvvfdldnnrvglAe 314
                 +++l++++   ++Ci+g+     ++++dl+iLGd+F +++ +vfd+++ ++ +A+
  EEA23085.1 384 DMILYVGD---NTCISGIedgGDDPSQDLYILGDTFQKNVVSVFDIGAVEMKFAP 435
                 *******8...78*****9988999**************************9996 PP

>> TAXi_N  Xylanase inhibitor N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5   1.1   3.1e-08   0.00011       2     177 ..     101     269 ..     100     270 .. 0.66

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 3.1e-08
      TAXi_N   2 lvsisiGtppqplklvvDtGsdltWvqCkpckacssqkkpvfdpsksstykavpcssslCkaceasssaksgsssstceyeisygadgssssGvlatdt 100
                  ++i+iGt  q++ +++DtGs+ tWv      + +++ ++  ++++s++y ++             + +k  + +++ +++i yg dg + +G ++t++
  EEA23085.1 101 ATEIKIGT--QTFEVILDTGSSDTWVVE----SGFKCVDVSTKKNESESYCNFGTP---------YKVEKTFKTNKNERFKIGYG-DGEFLTGIMGTEA 183
                 6899***9..5**************977....344455555555555555444444.........34455667778889*****8.999********** PP

      TAXi_N 101 ltlsstdgksvkvpnlvfGCgksnlgglaa.gadGilGLGrgk.lSlvsqlaskg.............slgnkFsyCLssssssssgvlffG 177
                 +t+      ++kv++ +++ ++   g   +  ++G++G+++ +  S  s  ++++              + + Fs+ +  + s  sg+l++G
  EEA23085.1 184 VTM-----AGIKVEHQTIALAN-YAGWYGDgTTSGLAGFAYPAlTSAFSSNGTQKvynplfttmykegLVDSYFSLAILRDVSGPSGYLTLG 269
                 ***.....78899999999887.34444441599*****99663344555554443333333333333555555555555555555566555 PP

>> Asp_protease_2  Aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.6   0.1      0.25   8.9e+02      13      79 ..      15      85 ..       4      94 .. 0.60
   2 !    9.4   0.1   0.00045       1.6       2      26 ..     103     127 ..     102     211 .. 0.89
   3 !    8.4   0.0   0.00093       3.3       9      68 ..     319     378 ..     305     411 .. 0.76

  Alignments for each domain:
  == domain 1  score: 0.6 bits;  conditional E-value: 0.25
  Asp_protease_2 13 llDTGasttlispelaekl..glkvreseltvrvsgaggevkarlvrldslklgg..ltlknvpalvldlg 79
                    ll  Ga++t i +   ++    l+ ++ + t  +++++ +++  +v+l++++ g+  +++ n++ l ++  
      EEA23085.1 15 LLSLGADATPIKSNKSHRNrrSLDSTTWKPTAFAESSSLSKSPNYVQLKKVTGGSarHSAANLKGLTTPTA 85
                    55556666666555554442255666666566667777778888888888888873344555555555555 PP

  == domain 2  score: 9.4 bits;  conditional E-value: 0.00045
  Asp_protease_2   2 pvtinGkpvrfllDTGasttlispe 26 
                     +++i+ ++++++lDTG+s t + ++
      EEA23085.1 103 EIKIGTQTFEVILDTGSSDTWVVES 127
                     6788889***********9987665 PP

  == domain 3  score: 8.4 bits;  conditional E-value: 0.00093
  Asp_protease_2   9 pvrfllDTGasttlispelaeklglkvreseltvrvsgaggevkarlvrldslklggltl 68 
                      +r+++D+G + ++ ++++a++ +   ++ ++    +ga     ++++ ++s+++gg ++
      EEA23085.1 319 GARYIVDSGTTLNYYPTSMANAVNAAFSPPAVYNATQGAYVVDCKATAPAHSITIGGKEF 378
                     4699***********************997766666666666667888999999999554 PP

>> TAXi_C  Xylanase inhibitor C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0      0.93   3.3e+03      29      52 ..     109     132 ..     101     153 .. 0.74
   2 !   12.2   0.2   3.1e-05      0.11       2     160 ..     300     434 ..     299     435 .. 0.72

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.93
                 ---SEEE-SSSSSEEE-HHHHHHH CS
      TAXi_C  29 gsggtvlstgtpytvletdvYral 52 
                 ++  ++l+tg++ t ++++ ++ +
  EEA23085.1 109 QTFEVILDTGSSDTWVVESGFKCV 132
                 456788888888888777777655 PP

  == domain 2  score: 12.2 bits;  conditional E-value: 3.1e-05
                 EEEEEEEEEETTEEE-------EE-S----SEEE-SSSSSEEE-HHHHHHHHHHHHHTS-GG...GE---TT-S-EEETTS......-S----EEEEES CS
      TAXi_C   2 YyipvkgisvngkrlplpasaldldktgsggtvlstgtpytvletdvYralvkafakelaaekvkrvaavkpfelCynsselgstragpavPtitlvle 100
                 Y i+v +i++ngk+l+  ++a           ++++gt++ + +t++ +a+ +af+  +  +     a++++    y  +       ++++P+ ++   
  EEA23085.1 300 YTIEVDNINLNGKALSSVSGA---------RYIVDSGTTLNYYPTSMANAVNAAFSPPAVYN-----ATQGA----YVVDC------KATAPAHSITIG 374
                 888888888888888877776.........57888888888888888777777776555443.....12222....33332......445566666666 PP

                 SS-EEEE-GGGGEEE-SSSEEEE-EEE-..-S--SSSEEE-HHHHBTS-EEEETTTTEEEEE CS
      TAXi_C 101 ggaewtisgenllvkveggvvClafves..gvagesavviGglqlednllvFDleksrlgFs 160
                  g+e+ +++ ++++ v ++ +C+  +e   +++++  +++G   +++++ vFD+ + +++F+
  EEA23085.1 375 -GKEFIVNPLDMILYVGDN-TCISGIEDggDDPSQDLYILGDTFQKNVVSVFDIGAVEMKFA 434
                 .789999999999998777.67766666688888999999*************999999997 PP

>> gag-asp_proteas  gag-polyprotein putative aspartyl protease
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.1   0.0   6.2e-05      0.22       2      41 ..     103     142 ..     102     192 .. 0.85
   2 ?    3.1   0.0     0.039   1.4e+02      11      67 ..     321     377 ..     300     386 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 6.2e-05
                      EEEETTEEEEEEEETT-SS-EEEHHHHHHTTGGGGEB..T CS
  gag-asp_proteas   2 kvkingkpvkflvDTGAsstiiseelaerlglsrkedkgk 41 
                      ++ki  +++++++DTG s+t + e+  + + +s+k+++++
       EEA23085.1 103 EIKIGTQTFEVILDTGSSDTWVVESGFKCVDVSTKKNESE 142
                      789*******************999999999999886543 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.039
                      EEEEETT-SS-EEEHHHHHHTTGGGGEB..TT--EE-TTSTT-EEEEEEEEEE.EET CS
  gag-asp_proteas  11 kflvDTGAsstiiseelaerlglsrkedkgkvevktangeveakrvrldsvkiggie 67 
                      +++vD+G +    ++++a++++   ++ +     + a  +  ++++  +s++igg e
       EEA23085.1 321 RYIVDSGTTLNYYPTSMANAVNAAFSPPAVYNATQGAYVVDCKATAPAHSITIGGKE 377
                      689*****************9999888444444444444444556677788888765 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (445 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       347  (0.0193541); expected 358.6 (0.02)
Passed bias filter:                      267  (0.0148921); expected 358.6 (0.02)
Passed Vit filter:                        24  (0.00133861); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.58u 0.24s 00:00:00.82 Elapsed: 00:00:00.46
# Mc/sec: 2879.12
//
Query:       EEA23086.1  [L=485]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.9e-10   39.3   0.2    1.7e-09   37.5   0.2    1.8  1  Fringe    Fringe-like
    2.5e-07   30.4   0.0    4.2e-07   29.6   0.0    1.3  1  DUF604    Protein of unknown function, DUF604


Domain annotation for each model (and alignments):
>> Fringe  Fringe-like
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.5   0.2   1.9e-13   1.7e-09      84     163 ..     231     300 ..     174     313 .. 0.81

  Alignments for each domain:
  == domain 1  score: 37.5 bits;  conditional E-value: 1.9e-13
      Fringe  84 eskkkWfchvDDDny.lnveaLlklLskynhtqdvylGkpsldrpieaterteenkkkkvkfwfatGGaGfclsralalkl 163
                 + ++kWfc++DDD++ l++++Ll++L+ky+ t+  y+G    +               ++   fa GGaG+ +sr l+ +l
  EEA23086.1 231 RPETKWFCIMDDDTFfLSMSRLLQMLDKYDVTKPHYIGTVTESDSQL-----------SMFGIFAYGGAGMFFSRPLMDEL 300
                 45679*********549*********************754333222...........23337999**********99877 PP

>> DUF604  Protein of unknown function, DUF604
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.6   0.0   4.7e-11   4.2e-07       9      92 ..     283     363 ..     276     378 .. 0.90

  Alignments for each domain:
  == domain 1  score: 29.6 bits;  conditional E-value: 4.7e-11
      DUF604   9 mafGGgGfaiSyplakaLakvldeClerYpklygsddriqaClaelG.vpltkekGfHqvDlrgdllGlLaahplaplvslHHld 92 
                  a+GG+G+  S pl  +L ++  eC          d +i  C+ +    +l  e+G+ q+Dl  d++G   a    p vslHH +
  EEA23086.1 283 FAYGGAGMFFSRPLMDELGRIWGECDAGTD---HGDGKIAHCVYQYTrTKLEIETGLNQLDLMTDASGWFEAARSVP-VSLHHWK 363
                 59***********************76555...5899******9875379**********************99999.8****75 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (485 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       465  (0.0259356); expected 358.6 (0.02)
Passed bias filter:                      424  (0.0236488); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.39
# Mc/sec: 3771.66
//
Query:       EEA23087.1  [L=126]
Description: hypothetical protein PMAA_096820 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (126 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       721  (0.0402142); expected 358.6 (0.02)
Passed bias filter:                      324  (0.0180713); expected 358.6 (0.02)
Passed Vit filter:                        28  (0.00156172); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.40u 0.25s 00:00:00.65 Elapsed: 00:00:00.41
# Mc/sec: 928.14
//
Query:       EEA23088.1  [L=583]
Description: C6 transcription factor (AmyR), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    5.6e-14   51.8   1.0    1.2e-13   50.7   1.0    1.6  1  Fungal_trans  Fungal specific transcription factor domain
    1.2e-09   38.1  10.8      2e-09   37.4  10.8    1.4  1  Zn_clus       Fungal Zn(2)-Cys(6) binuclear cluster domain
     0.0064   16.5   1.6      0.012   15.6   1.6    1.4  1  Trypan_PARP   Procyclic acidic repetitive protein (PARP)
  ------ inclusion threshold ------
       0.11   12.1   0.6       0.22   11.2   0.6    1.4  1  DUF5336       Family of unknown function (DUF5336)
       0.71   10.3   4.3        1.5    9.2   4.3    1.6  1  CCDC53        Subunit CCDC53 of WASH complex
        1.7    8.5  10.3        2.3    8.1  10.3    1.3  1  TFIIA         Transcription factor IIA, alpha/beta subunit


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   50.7   1.0   4.1e-17   1.2e-13       1     178 [.     201     376 ..     201     407 .. 0.79

  Alignments for each domain:
  == domain 1  score: 50.7 bits;  conditional E-value: 4.1e-17
  Fungal_trans   1 ldrffsnfhpqfpilhkpsflpkt.ssenssksayaspllllailalGalfsesetkesnssltses....qefiafplraeilihedfsspssslw 92 
                   ++++ ++++p +p+++ +++l++  + e+ ++ +ya+   l a  ++  ++  +++ +s+ss  ++s       i + l  +i   ++++   ++++
    EEA23088.1 201 INVYLKYLYPIIPVVNPEQILNDSqHPEQLTIQRYAFLTALCAATHVQLQLDAMIDPSSSSSYYDSSlalsG--I-EILTEAISARNECVNICEQVT 294
                   679*********************888888888888888888888888888888888888888877765331..2.334555555555555555444 PP

  Fungal_trans  93 ilq...sLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaaFylDktialklGrpplldd 178
                   i     s++l++ y  +++++++++ +++ a +la +lgLhr+  y+         eeeae+rrR++w  F++++ +al+  rp +l++
    EEA23088.1 295 IESlltSFFLFAAYG-NLDRQDQAWFYLSQATSLALTLGLHREATYST------FGEEEAEERRRVFWLLFVTERAYALQQARPIMLRN 376
                   433322444554443.55679***************************......99***********************9999986655 PP

>> Zn_clus  Fungal Zn(2)-Cys(6) binuclear cluster domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.4  10.8   6.7e-13     2e-09       1      39 [.      23      60 ..      23      61 .. 0.92

  Alignments for each domain:
  == domain 1  score: 37.4 bits;  conditional E-value: 6.7e-13
                SS-HHHHHCT---STSSSS-HHHHHCTHHHCCCCTCCCE CS
     Zn_clus  1 haCdnCrkkKvKCdakkPaCsnCkklnleCtfysesskr 39
                +aCdnCr++K+KC++ +P C +C++l l C++y+  +++
  EEA23088.1 23 QACDNCRRRKIKCNRAQP-CDKCQRLLLSCSYYDVLQRK 60
                69****************.************99887665 PP

>> Trypan_PARP  Procyclic acidic repetitive protein (PARP)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.6   1.6     4e-06     0.012      84     113 ..     156     185 ..     137     201 .. 0.58

  Alignments for each domain:
  == domain 1  score: 15.6 bits;  conditional E-value: 4e-06
  Trypan_PARP  84 eeepepepepepepepepepepepepepga 113
                   ++p+p+p+p+p+p+++p+ +p+p+p+p +
   EEA23088.1 156 SNQPQPQPQPQPQPQAQPQQQPQPQPQPQS 185
                  334444444444444444444444444444 PP

>> DUF5336  Family of unknown function (DUF5336)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.6   7.2e-05      0.22       5      93 ..     159     245 ..     155     249 .. 0.58

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 7.2e-05
     DUF5336   5 paqqgqqyggptqsfakqeeaqaaagpskLplyLsiavaaLGliayllgFgplltvsassadleeasatsgglglavvllLlagLlAgv 93 
                 p++q+q++++p+ +  +q+++q++ +++  +  Ls+ v+   + +yl    p++ v + + +  + s    +l ++   + l +L A++
  EEA23088.1 159 PQPQPQPQPQPQAQPQQQPQPQPQPQSRTQSGRLSAMVILAHINVYLKYLYPIIPVVNPE-QILNDSQHPEQLTIQ-RYAFLTALCAAT 245
                 344444444444444455666666666677778888888888999999998888888877.333333333333332.344455666665 PP

>> CCDC53  Subunit CCDC53 of WASH complex
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.2   4.3    0.0005       1.5      67     125 ..     143     207 ..      78     220 .. 0.56

  Alignments for each domain:
  == domain 1  score: 9.2 bits;  conditional E-value: 0.0005
      CCDC53  67 aarkgppppppsseaaaaaaqaeea.sqaeesaeeeaeeqeesesk.......nvltvkdDpryakY 125
                 a  ++pp+++p ++++ ++++++++ +qa+ +++++++ q++s  +       +++ ++   +y kY
  EEA23088.1 143 AMLSQPPSQSPLMSNQPQPQPQPQPqPQAQPQQQPQPQPQPQS--RtqsgrlsAMVILAHINVYLKY 207
                 2333333333343333333322222022222222222222222..1346666555555555666666 PP

>> TFIIA  Transcription factor IIA, alpha/beta subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.1  10.3   0.00077       2.3     169     228 ..     126     185 ..      13     269 .. 0.61

  Alignments for each domain:
  == domain 1  score: 8.1 bits;  conditional E-value: 0.00077
       TFIIA 169 saaqssvaalqaqsqqaqalaepqqq.lekqqqqqqqqqqqqqqqqvqqqqqeesqqaqqa 228
                   +q ++++ +++ +q+++l++p +q   +++q+q q+q q q+q +q qqq ++q ++q+
  EEA23088.1 126 VDSQYELPNTSSGYHQTAMLSQPPSQsPLMSNQPQPQPQPQPQPQ-AQPQQQPQPQPQPQS 185
                 222333333333344444444444442222222222111111111.111111111111111 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (583 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       789  (0.0440069); expected 358.6 (0.02)
Passed bias filter:                      418  (0.0233142); expected 358.6 (0.02)
Passed Vit filter:                        61  (0.00340231); expected 17.9 (0.001)
Passed Fwd filter:                        10  (0.000557756); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.66u 0.29s 00:00:00.95 Elapsed: 00:00:00.46
# Mc/sec: 3820.26
//
Query:       EEA23089.1  [L=616]
Description: glucoamylase precursor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
   1.7e-102  343.5   0.8   2.1e-102  343.2   0.8    1.1  1  Glyco_hydro_15  Glycosyl hydrolases family 15
    1.6e-28   98.4   0.2    4.4e-28   97.0   0.2    1.8  1  CBM_20          Starch binding domain


Domain annotation for each model (and alignments):
>> Glyco_hydro_15  Glycosyl hydrolases family 15
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  343.2   0.8  2.3e-106  2.1e-102       2     447 ..      41     456 ..      40     457 .. 0.97

  Alignments for each domain:
  == domain 1  score: 343.2 bits;  conditional E-value: 2.3e-106
                     HHHHHHHHCBCSTTSSBTTS-TT-B-S-S-BSSSB--SEEHHHHHHHHHHHH.......HHHHHTTT-HCCHHHHHHHHHHHHHHCTS-BTTB-T CS
  Glyco_hydro_15   2 vrldlylrnvktlilleqnpvtGlliASpstsdpDYrytWvRDsvyvilavwglgyrdedrakayeleqslvklmrglleamvrqagkvekfket 96 
                     v+l+++l+n+++ ++ ++++ +G + ASps+ dp Y+ytW+RDs++++++++        + ++ +   sl+ +++++++  + ++g ++++++ 
      EEA23089.1  41 VALQGVLNNIGSSGAFTEGADAGSVLASPSKADPNYFYTWTRDSALTLKTLI--------DNFIAG-TSSLESTIQEYINVETIIQGISNPSGSL 126
                     789*************************************************........889999.89************************** PP

                     TSCGGGG--EE-TTS-B--S-..-S--BTTHHHHHHHHHHHH....HCTT..HCHCCCCHHHHTHHHHHHHHHHHTTS-EE-TTS--ECEEHH.. CS
  Glyco_hydro_15  97 qstkgLhakyftktgstvvGddewghlQlDatslyllalaqm....tasg..lqiistldevafvqnlvdYieaayktpdfglWEenqgeselna 185
                      +++gL++++f+++g++++G+  wg++Q+D+++l+++a++++    +++g  +++++ ++++  vqn++ Y++++++++ f+lWEe qg+s++  
      EEA23089.1 127 ADGTGLGEPKFNVNGTAFTGS--WGRPQRDGPALRATAMIAYanylINNGqtSTAKEIIWPI--VQNDLAYVAQYWNQTTFDLWEETQGSSFF-- 215
                     *********************..**********************9999999999999****..*****************************.. PP

                     HHHHHHHHHHHHHHHHHHCT-HHHHCCHHHHHHHHHHHHHSTTT..GGGEETTCCECECSCH.....HHHTTS--S-BCHHHHHHHHCS-TTS.- CS
  Glyco_hydro_15 186 ssvgmakAlleaideadlfgakgdaqlvektkdeilnklqgkygckrgfwplfntylildgsfaedkeqvqeyrealdasllllpelyfvpad.d 279
                     +++++++Al+e+ ++a+++g  +++  + ++++++l+ l       +++w+    y+ ++ +        q+ r +lda+ +l+++ +f+pa+ +
      EEA23089.1 216 TTAAQHRALVEGSALATSLG--QSCANCVSQAPQVLCFL-------QSYWTG--SYILANFA--------QNGRTGLDANSILGVIETFDPAAtS 291
                     ********************..9999*************.......****95..55555555........56*******************8636 PP

                     TT-TT-TTTSHHHHHHHHHHHHHHHHHSGGGTT-STTS...--SBTT--CGSSSBSCT--BHHHHHHHHHHHHHHHHHHHHHTE-EEEECCCHHH CS
  Glyco_hydro_15 280 vdeeyqnpqsprllaqslyildsllsegflavgeldpl...vrRysedvkpdklglsGrpyylctlwtvetlldelyekagkgrlwglvryalgl 371
                     +d+ +++p+s ++la++++++ds++s ++l++g  +++   v+Ry edv++      G+p+yl+t++++e+l+d++y++++ g+ +++++ +lg+
      EEA23089.1 292 CDDATFQPCSAKALANHKAVTDSFRSVYTLNSGIAAGSavaVGRYAEDVYQ-----GGNPWYLSTTAAAEQLYDAIYQWNKIGS-ITITSVSLGF 380
                     9**********************************999************8.....**************************99.********** PP

                     HHHHTTTTTGGGSSEEE.TCHHHHHHHHHHHHHHHHHHHHHH.S-TTS---SEE-TTT--EESSTT-HHHHHHHHHHH CS
  Glyco_hydro_15 372 leklveskqltvGlppe.resvisaplpveeladliveavee.dnslgvLteevdvylgeliraqpllfsealllrig 447
                     +++++ s  +++G++++ +++++ ++ +v+++ad ++++ve+ ++ +g L+e++ +++g +++a+ l++s+a+ll+++
      EEA23089.1 381 FRDIYPS--AATGTYASgSSTFTAIIAAVQKYADGYMSIVEKyTPADGTLAEQFQRDTGAPLSASALTWSYAALLTAA 456
                     *******..******************************************************************986 PP

>> CBM_20  Starch binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   97.0   0.2   4.9e-32   4.4e-28       1      95 [.     513     608 ..     513     610 .. 0.94

  Alignments for each domain:
  == domain 1  score: 97.0 bits;  conditional E-value: 4.9e-32
      CBM_20   1 tvsVtFkvnattqlgesvyivGsiseLGnWnp..kkavklsaseqtssyplWsttvslpagtkieYkyikkdsdgsvtWesgenrsltvpssgsstt 95 
                 +v+VtF+  +tt++g++vy++G+is+LG+W++   kav lsa+ + s y+lW++t++lp+gt++eYk+ k++s  ++tWes++nr++ vps++ ++t
  EEA23089.1 513 KVAVTFQEVVTTSFGQNVYLTGNISALGSWSTtaGKAVLLSAQDYRSAYNLWYVTLNLPSGTAFEYKFFKNASG-TITWESDPNRKYIVPSDCGVST 608
                 589*****99*********************944589********************************99886.******************9876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (616 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       545  (0.0303977); expected 358.6 (0.02)
Passed bias filter:                      359  (0.0200234); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.57u 0.29s 00:00:00.85 Elapsed: 00:00:00.44
# Mc/sec: 4181.51
//
Query:       EEA23090.1  [L=497]
Description: alpha-amylase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    9.2e-65  219.4   0.1    1.2e-64  219.0   0.1    1.1  1  Alpha-amylase  Alpha amylase, catalytic domain
    1.2e-27   96.0   0.2    2.4e-27   95.0   0.2    1.5  1  DUF1966        Domain of unknown function (DUF1966)
  ------ inclusion threshold ------
       0.12   12.3   1.8        5.2    6.9   0.0    2.5  3  GHL15          Hypothetical glycosyl hydrolase family 15


Domain annotation for each model (and alignments):
>> Alpha-amylase  Alpha amylase, catalytic domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  219.0   0.1     2e-68   1.2e-64       1     337 []      61     362 ..      61     362 .. 0.93

  Alignments for each domain:
  == domain 1  score: 219.0 bits;  conditional E-value: 2e-68
                    --CHHHHCTCCCCCCCT-SCEEE-B-CE.......-S-TTTTSS-SCECCE-CCC--CCCCCCHHHHHHCTT-EEEEEE--SC--TTSCCCHCCHH CS
  Alpha-amylase   1 GDLkGiiekLdYlkeLGvtaiwlsPifk.......spqadhgYdiadytkidpefGtnedlkeLiskahekgikvilDlVvNHtsdehewfkeslk 89 
                    G ++Gii++LdY++++G+taiw++P+++         +a hgY+++d+++i+ ++Gt+edlk+L++++h++g+++++D+V+NH++++ +  + +++
     EEA23090.1  61 GSWRGIINQLDYIQNMGFTAIWITPVTEqlpqstgDGTAFHGYWQQDIYSINSNYGTAEDLKALSTALHARGMYLMVDVVANHMGYAGAGTDVDYS 156
                    88*****************************999988999******************************************************** PP

                    STTSGGGCCC-E......ESS-STTC-TTTTCSCEECTTTTCEEESSS-TTS-BB-TTTCCCCCCCCC.CCCCCCTTT-SEEEETTCCCTTTCCCC CS
  Alpha-amylase  90 kkgepkrdyyiwkegkeekeppnnwkslfdgsaweydekaqeyylhlflkklpdLnteneevrkelkd.vvkfwlekgidGfRlDvvkhvskveal 184
                      ++ +++ y+ +       p+    ++ + +++e +++++      ++ +lpdLnte+ ev++ ++  + +++ + +idG+RlD + +v+k    
     EEA23090.1 157 VFNPFNSQSYF-H-------PYCPIINYSNFTMVEQCWEGD------NTVSLPDLNTESTEVQNIWYSwIPELVSNYSIDGLRLDSALEVQK---- 234
                    ***99999999.3.......455555567778888776665......7********************999*********************.... PP

                    HCCHCCHHHHHHHHHHHTCCGTT-EEEEE-TT-SCCCHCCCC-CGG-SICECCITTCGGGCC-CTSTTSB-SS-HHHHHHHHHHHHHHS-CCCTTC CS
  Alpha-amylase 185 esngeflheftqalnetvasrkevmtvgEvssdasedlrvyttearlelemvldfphldvaqkakikeqlksisakklkellkkwlkaleeaaeea 280
                        +f+  + +a+         v++vgEv++++   + ++ ++++l+    l++p +    +a+   +++s s+ +l+++++++++++++ ++  
     EEA23090.1 235 ----DFWPAWVKAAG--------VYCVGEVFNGDA--TVACPYQNYLDGV--LNYPTYFPMIRAF---ESTSGSISDLYNMVNTVQSDCSD-SNLL 310
                    ....*********99........89*******888..6888899999999..9999999888888...788889****************9.99** PP

                    EEES--TTS--HHHHTTSSTTTTHHHHHHHHHCCCTSSSEEEEETTCCCT----STT CS
  Alpha-amylase 281 vtflgnHDqeRilsrlgddsaeaekklklaaillltlrGvpviYyGeEigmtggkdp 337
                     tf +nHD++R++s+++d s      +k++++++l+++G+p+iY G+E+++ gg dp
     EEA23090.1 311 GTFSENHDNPRFASYTSDFS-----LAKNVLAFTLLSDGIPIIYAGQEQHYNGGSDP 362
                    ********************.....8***************************9987 PP

>> DUF1966  Domain of unknown function (DUF1966)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   95.0   0.2   4.1e-31   2.4e-27       1      87 [.     407     493 ..     407     495 .. 0.97

  Alignments for each domain:
  == domain 1  score: 95.0 bits;  conditional E-value: 4.1e-31
     DUF1966   1 plysdkstlalrKgpegsqvvtvlsnkGssgssytlslkssgyaagtevvdvlsCksvtvdssgeltvtmekGePrvlvpksklegs 87 
                 p+y+d++++alrKg+ gsqvvtv+sn+Gss++sy+l+++++g++ag+ ++++++C++vtv +sg+++v+m+ G   vl+p+skl g 
  EEA23090.1 407 PIYQDSNNIALRKGSTGSQVVTVFSNSGSSAGSYSLKISGTGFNAGQVITELITCTNVTVSDSGDISVPMAGGLTSVLYPASKLVGD 493
                 79********************************************************************************99775 PP

>> GHL15  Hypothetical glycosyl hydrolase family 15
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.9   0.0   0.00087       5.2      67     136 ..      73     144 ..      52     192 .. 0.75
   2 ?    4.4   0.1    0.0051        31      67     104 ..     199     236 ..     177     253 .. 0.83
   3 ?   -3.0   0.0      0.91   5.4e+03     171     203 ..     368     402 ..     348     415 .. 0.47

  Alignments for each domain:
  == domain 1  score: 6.9 bits;  conditional E-value: 0.00087
       GHL15  67 vsnpefrewWvksalnelrdsgiDGvfaDndvktlsyysldlplsgvae.ii..daklregldellkelkeal 136
                 + n++f+  W++ ++++l +s  DG     + +  + ys++     +++ ++   a+ + g+  ++  + +++
  EEA23090.1  73 IQNMGFTAIWITPVTEQLPQSTGDGTAFHGYWQ-QDIYSINSNYGTAEDlKAlsTALHARGMYLMVDVVANHM 144
                 4699*********************99999999.677886664444444422456667777778888888887 PP

  == domain 2  score: 4.4 bits;  conditional E-value: 0.0051
       GHL15  67 vsnpefrewWvksalnelrdsgiDGvfaDndvktlsyy 104
                   ++e+++ W  ++ + +++  iDG  +D++++  +++
  EEA23090.1 199 TESTEVQNIWYSWIPELVSNYSIDGLRLDSALEVQKDF 236
                 55689**********8888888*********9965543 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 0.91
       GHL15 171 eslltmdealalgkd..qaarqpkivilqkafqds 203
                  +l  +d+  +l +   q ++  ++vi q+  +++
  EEA23090.1 368 TWLSGFDTSAELYQWvaQMNKIRNFVIKQDTGYTT 402
                 34444444333333211223334555554444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (497 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       500  (0.0278878); expected 358.6 (0.02)
Passed bias filter:                      403  (0.0224776); expected 358.6 (0.02)
Passed Vit filter:                        25  (0.00139439); expected 17.9 (0.001)
Passed Fwd filter:                         3  (0.000167327); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               3  [number of targets reported over threshold]
# CPU time: 0.52u 0.29s 00:00:00.81 Elapsed: 00:00:00.43
# Mc/sec: 3478.76
//
Query:       EEA23091.1  [L=311]
Description: homeobox transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    5.8e-21   74.1   0.3    5.8e-21   74.1   0.3    1.8  2  Homeobox_KN  Homeobox KN domain
    1.1e-06   28.3   0.6    2.2e-06   27.4   0.1    1.7  2  Homeodomain  Homeodomain


Domain annotation for each model (and alignments):
>> Homeobox_KN  Homeobox KN domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.3   0.2         2   1.8e+04       9      12 ..      64      67 ..      63      68 .. 0.83
   2 !   74.1   0.3   6.5e-25   5.8e-21       1      40 []     225     264 ..     225     264 .. 1.00

  Alignments for each domain:
  == domain 1  score: -4.3 bits;  conditional E-value: 2
  Homeobox_KN  9 PYPs 12
                 PYP 
   EEA23091.1 64 PYPH 67
                 9**5 PP

  == domain 2  score: 74.1 bits;  conditional E-value: 6.5e-25
  Homeobox_KN   1 WflahlhnPYPseedKeeLlkeTglsvkqitnWFINaRrR 40 
                  Wf++hl++PYP+eedK+ ++ +Tgls++qi+nWFINaRrR
   EEA23091.1 225 WFHEHLDHPYPTEEDKQIFMSRTGLSISQISNWFINARRR 264
                  ***************************************9 PP

>> Homeodomain  Homeodomain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.0       1.2   1.1e+04      17      27 ..     152     162 ..     151     164 .. 0.80
   2 !   27.4   0.1   2.5e-10   2.2e-06       1      55 [.     208     265 ..     208     265 .. 0.93

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 1.2
                  HHHHHSSS-SH CS
  Homeodomain  17 klFeenrypsa 27 
                  + ++ ++yps+
   EEA23091.1 152 QSYHGSSYPSS 162
                  6799999**97 PP

  == domain 2  score: 27.4 bits;  conditional E-value: 2.5e-10
                  ST-SSSS-HHHHHHHHHHHHH...SSS-SHHHHHHHHHHHTS-HHHHHHHHHHHHHHH CS
  Homeodomain   1 rrkRttftkeqleeLeklFee...nrypsaeereeLAkklgLeerqVkvWFqNrRake 55 
                  +r+R ++ k  +++L + F+e   ++yp++e+++   +++gL+ +q+++WF N R ++
   EEA23091.1 208 KRRRGNLPKPVTDVLRAWFHEhldHPYPTEEDKQIFMSRTGLSISQISNWFINARRRQ 265
                  7899999999**********65569******************************885 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (311 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       516  (0.0287802); expected 358.6 (0.02)
Passed bias filter:                      300  (0.0167327); expected 358.6 (0.02)
Passed Vit filter:                        19  (0.00105974); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.47u 0.26s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 2154.31
//
Query:       EEA23092.1  [L=314]
Description: carboxyphosphonoenolpyruvate mutase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model      Description
    ------- ------ -----    ------- ------ -----   ---- --  --------   -----------
    1.4e-34  119.6   0.2    1.9e-34  119.2   0.2    1.2  1  PEP_mutase  Phosphoenolpyruvate phosphomutase
    1.6e-21   76.5   0.1    1.9e-21   76.1   0.1    1.1  1  ICL         Isocitrate lyase family


Domain annotation for each model (and alignments):
>> PEP_mutase  Phosphoenolpyruvate phosphomutase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  119.2   0.2   2.1e-38   1.9e-34       2     194 ..      49     249 ..      48     277 .. 0.87

  Alignments for each domain:
  == domain 1  score: 119.2 bits;  conditional E-value: 2.1e-38
  PEP_mutase   2 ra.LhakgeplvlpnawDalsakiveeagfkalatsSlavaasl.GvpDgeelpleellaavraiaevvs..lPlivDledGygespeevaetvrrlia 96 
                 r+ L + +e++v p ++D+lsa+i+ +  fkal +++++++as  G++D   ++l  + ++++ ia+      Pli+D+++Gyg  p  va+ v++ i+
  EEA23092.1  49 RRmLTEANEMIVCPGVYDGLSARIAMQLDFKALYMTGAGTTASRlGMADLGLAQLHDMKTNAEMIANLDPngPPLIADMDTGYGG-PLMVAKSVQQYIQ 146
                 66699999******************************9999988*****99999999999998888553569***********9.99*********** PP

  PEP_mutase  97 aGvvgvniEDk....kknd.aerqlldieefaekiaaaraaaeeag..fvinARtdalllsagagleeaieRaraYaeAGAdgvfvpglqkdaeiael. 187
                 aGv+g++iED+    +++  a++++++ ee + ++++a+ + +  +  +v++ARtdal    + g ee i+R++a  + GAd+ +  gl+++++ ++  
  EEA23092.1 147 AGVAGFHIEDQvlskRCGHlAGKKVVSKEEYLMRLRTAKYTIDRLQsdIVLIARTDALQ---QHGYEECIDRLKAARDLGADVGLLEGLTSKEQARQAe 242
                 ***********986433356999******************9998889*********66...6778***********************9999954430 PP

  PEP_mutase 188 vaavdvp 194
                 +a+++ +
  EEA23092.1 243 AAEMGFR 249
                 3333444 PP

>> ICL  Isocitrate lyase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.1   0.1   2.2e-25   1.9e-21     137     244 ..     107     214 ..     100     245 .. 0.87

  Alignments for each domain:
  == domain 1  score: 76.1 bits;  conditional E-value: 2.2e-25
                 HHHHTTS------.--EEEE-TT-SSSHHHHHHHHHHHHHTT-SEEEE-SB-TT---------EEE--HHHHHHHHHHHHHHHHHTT---EEEEE--GG CS
         ICL 137 keereklanvdyl.rpiiadadtGhGGltavvkltklfierGaaGihiedqasgtkkcGhmaGkvlvpiqehinrlvairaqadilgsdllvvartdse 234
                 k + e++an+d    p+iad dtG+GG   v k ++ +i+ G aG hiedq   +k+cGh+aGk +v+ +e++ rl +++ ++d l+sd++++artd+ 
  EEA23092.1 107 KTNAEMIANLDPNgPPLIADMDTGYGGPLMVAKSVQQYIQAGVAGFHIEDQV-LSKRCGHLAGKKVVSKEEYLMRLRTAKYTIDRLQSDIVLIARTDAL 204
                 5667888888865158***********************************7.579*****************************************97 PP

                 GEEEES-TT- CS
         ICL 235 aatlitstid 244
                      +  id
  EEA23092.1 205 QQHGYEECID 214
                 6666666665 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (314 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       392  (0.021864); expected 358.6 (0.02)
Passed bias filter:                      375  (0.0209158); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.46u 0.23s 00:00:00.69 Elapsed: 00:00:00.41
# Mc/sec: 2308.41
//
Query:       EEA23093.1  [L=146]
Description: hypothetical protein PMAA_096880 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (146 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       386  (0.0215294); expected 358.6 (0.02)
Passed bias filter:                      217  (0.0121033); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.38u 0.26s 00:00:00.64 Elapsed: 00:00:00.41
# Mc/sec: 1072.46
//
Query:       EEA23094.1  [L=641]
Description: FAD binding domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    5.1e-45  153.7   0.0    7.5e-45  153.2   0.0    1.2  1  FAD_binding_1  FAD binding domain
    2.1e-10   41.2   0.0    9.3e-10   39.1   0.0    2.1  2  NAD_binding_1  Oxidoreductase NAD-binding domain


Domain annotation for each model (and alignments):
>> FAD_binding_1  FAD binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  153.2   0.0   8.4e-49   7.5e-45       7     222 .]     221     454 ..     215     454 .. 0.94

  Alignments for each domain:
  == domain 1  score: 153.2 bits;  conditional E-value: 8.4e-49
                    B-EEEEEEEEEE---.-SS--EEEEEEE-TTB.....T----TT-EEEE-----HHHHHHHHHHHT--T...T-EEEEEESSTT......S--SSS CS
  FAD_binding_1   7 kvflakvlknreLtkpesernvihveldisds.....glkYetGdhlgvypsNneelVeellellgldpk.adevvelkaldee....saekeprl 92 
                     vf+a++ + reLtkp++e+++ h+ +d+ d+     ++ + +G+++gv+p+N++++V+ + ++lg+ ++ +d+ + +++  ++    + +++ r+
     EEA23094.1 221 DVFRAPLHHARELTKPGAEKRTYHFDIDVTDYpieggDVDFVVGGAIGVCPMNSDDAVDGVFNCLGIPKPiRDKKILVRTTSGRwptiWGDEKARE 316
                    69*****************************99999899****************************99989**********999998899999** PP

                    SSEEHHHHHHHTB--SS.---HHHHHHHGGG-SSHHHHHHHHHHHH-HHHHHTTTTT--HHHHHHHHHTT---TTS-HHHHHHHS-B---EEEEB- CS
  FAD_binding_1  93 eptTlrqalkyylditg.ppskqlleaLaefaseeeekqkLekLssdegakeykelklneartllevleefpsvklplefLlevlpqLkpRyYSiS 187
                     +tT+r++l++  di + pp+kqll+ +ae+as+++ek+ L++L+s +g++ +++l+     ++ ++l++fps+ +pl+ Ll+vl  L+pR+YS+S
     EEA23094.1 317 LVTTRRELLRWCSDIQSyPPTKQLLRVMAEYASDPHEKKILTFLCSAQGQSVFCDLRTGVHVSIEQLLQAFPSSLPPLDYLLSVLGTLMPRFYSLS 412
                    *****************9****************************************************************************** PP

                    S-TTTTTTE........EEEEEE--EE---SSS--EE-HHHHH CS
  FAD_binding_1 188 ssskvhpde........vhltvvVveyetdgegrirkGvcsny 222
                     ++  + ++        ++++v+V + + d +  +r+Gv+s +
     EEA23094.1 413 QDPTISCTTrngdcrriIEIAVTVHKSK-DWKHGTRSGVGSGF 454
                    **99875443344445599999999999.699999****9976 PP

>> NAD_binding_1  Oxidoreductase NAD-binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.0   0.0      0.62   5.6e+03      10      40 ..     336     368 ..     335     372 .. 0.72
   2 !   39.1   0.0     1e-13   9.3e-10       1     108 [.     502     605 ..     502     606 .. 0.84

  Alignments for each domain:
  == domain 1  score: -2.0 bits;  conditional E-value: 0.62
                    HHHHHHHHHHHHCT..TCSEEEEEEEESSGCGS CS
  NAD_binding_1  10 Pvrsvlraileeak..dktkvvlvyGnrteedl 40 
                    P++++lr ++e a+  +++k+  + +  + +++
     EEA23094.1 336 PTKQLLRVMAEYASdpHEKKILTFLCSAQGQSV 368
                    888999999998444577778778777777665 PP

  == domain 2  score: 39.1 bits;  conditional E-value: 1e-13
                    EEEEGGGGHHHHHHHHHHHHHCTTCSEEEEEEEESSGC.GSTTHHHHHHHHHHCTTEEEEEEEESSCTTTSSSEESSHHHHHHHHHHH....HSST CS
  NAD_binding_1   1 miagGtGiaPvrsvlraileeakdktkvvlvyGnrtee.dllyreeleelakklpgrlkvvavvsreeagweggkgrvqdalleells....lkke 91 
                    +i++G+GiaP+r++++++l+ a+  +kv+++ G+r +  d ly+ e+   +++ ++      v     ++ +g+  +vq++++ +++     ++  
     EEA23094.1 502 LIGAGVGIAPFRGFVQRRLKSANCANKVWVLQGVRDSLlDELYSGEWGVHEEQVKK------V----VQSRRGESRYVQEEVRHQADLvwfvINAL 587
                    79*********************************998899999998877555555......3....2233344679999999999889999999* PP

                    TEEEEEEC.SHHHHHHHH CS
  NAD_binding_1  92 ethvyvCG.ppgMikavr 108
                    +  v+vCG  +gM ++v+
     EEA23094.1 588 DGRVFVCGsSKGMGEGVE 605
                    ********9999*98876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (641 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       498  (0.0277762); expected 358.6 (0.02)
Passed bias filter:                      423  (0.0235931); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.64u 0.30s 00:00:00.94 Elapsed: 00:00:00.50
# Mc/sec: 3827.03
//
Query:       EEA23095.1  [L=588]
Description: class I alpha-mannosidase [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
     1e-187  624.6   0.0   1.2e-187  624.4   0.0    1.0  1  Glyco_hydro_47  Glycosyl hydrolase family 47
  ------ inclusion threshold ------
      0.065   13.5   0.0       0.19   12.0   0.0    1.8  1  DUF4368         Domain of unknown function (DUF4368)


Domain annotation for each model (and alignments):
>> Glyco_hydro_47  Glycosyl hydrolase family 47
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  624.4   0.0  1.3e-191  1.2e-187       1     458 []     106     586 ..     106     586 .. 0.99

  Alignments for each domain:
  == domain 1  score: 624.4 bits;  conditional E-value: 1.3e-191
                     HHHHHHHHHHHHCTTSSEEETTTTEEE-SS.SS-CCHHHHHHHHHHCCHHHHHHHHHHHHHHC----S.SS.EEEHHHHHHHHHHHHHHHHHHH. CS
  Glyco_hydro_47   1 afkhswegYkkyAwghDelrPlskkgrdtfgglgatlvDsLdtllimglkeefeeaveavekkidfdtsdskevsvFEttIRyLGGLlsaydlse 95 
                     af h+w+gYk++Aw +De+ P+s+++ ++f+g++atlvD+Ldtllimgl+eef+ a++a+e +idf+t++ k+++vFEttIRy+GG+l+aydls+
      EEA23095.1 106 AFLHAWTGYKTHAWLKDEVLPISGGYVNSFSGWAATLVDALDTLLIMGLDEEFQLALDAIE-QIDFTTTTDKSINVFETTIRYMGGFLAAYDLSG 199
                     79***********************************************************.********************************* PP

                     S-HHHHHHHHHHHHHHHHGGGSSTTS---SEEETTT--EE-.STCGCEEEHHHHCSSHHHHHHHHHHHT-CHHHHHHHCCHHHHHCHCC.HHHTT CS
  Glyco_hydro_47  96 kkedvllekAveladrLlpAFdtpsglpvarvnlkkrkaskkerassesvlAelgslslEftrLsqlTgdkkYedlaervtkaleelqektklpg 190
                     +k++++l+kA++++d +++AFdtp+++ v+r+++k + a+++ ras ++ lAe+gslslEftrL+qlTgd+kY+d+++rv ++le+ q+kt++pg
      EEA23095.1 200 GKYPIILKKAKQVGDFVYGAFDTPNRMQVSRWDWKASLAGTPMRASPNTLLAEVGSLSLEFTRLTQLTGDPKYYDAIQRVSDNLEKGQSKTTIPG 294
                     **********************************************9*****************************************99***** PP

                     B-BSEEETTT--EESTEE-SSTTTHHHHHHHHHHHHHCTS--HHHHHHHHHHHHHHHHH.TEEE-TTT..--EEE-EECTTCTS.EE-EEEGGGG CS
  Glyco_hydro_47 191 lvpikidastgkfvaekislgargDSyYEYllKqylllggeeeqyrkmyeealdaikkhllfrpskkkeddllfvgevtsteegklspeidhLsc 285
                     l+p+ +d+++ kf++++++lg+++DS+YEYl+K++l+lgg+++qyr+mye++++ ikk+llfrp++k++ d+lf+g+++   +++l++e +hL+c
      EEA23095.1 295 LWPMIVDLQNLKFQGSQYTLGGMADSTYEYLPKEHLMLGGSTNQYRRMYEKSIEPIKKNLLFRPMVKDNVDILFSGTRN---GNTLDYEGQHLTC 386
                     *****************************************************************************85...788********** PP

                     HHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHHHHTSTTS---SEEEE-SS.....S-ECTSSSSEEE-........................... CS
  Glyco_hydro_47 286 FlgGllalgakllekeedlelAkkltegcvkayeatktglmPEifevkpcesaeecewneekkdealk........................... 353
                     F+gG++a+gak+++++edl++A++l++gc++ay+a++t+lmPEif++ pce+ ++c+w+e+k+  a+                            
      EEA23095.1 387 FIGGMFAIGAKIFDRPEDLKTAEQLVDGCIWAYDAMPTSLMPEIFKMIPCEDLDKCSWDEKKWLAAVAktahinalddetihkfikdaglppgmt 481
                     **************************************************************9999999************************** PP

                     .GGG--B----HHHHHHHHHHHHH--THHHHHHHHHHHHHHHHCEETTEE--ECETTSSS-EE-S-B-HHHHHTHHHHHHHHC-S-TTT-TTTEE CS
  Glyco_hydro_47 354 riedrkyllRPEaiESlfylYritgdekyrevgwemfealekatktesgysaledVtkeepekeDemeSFwlaEtlKYlYLlFsdedvlsldeyV 448
                     r+ d ky+lRPEaiES++++Yritgd+ky+e +w+mf+++ek t+t  ++++++dV+ +++ + D+meSFwlaEtlKY+YL+Fs++ ++sld+yV
      EEA23095.1 482 RVADGKYILRPEAIESVYIMYRITGDNKYQEAAWRMFSSIEKMTRTAIAHASIKDVRFTDSMQVDKMESFWLAETLKYFYLIFSEPGLVSLDDYV 576
                     *********************************************************************************************** PP

                     E-TTS-EEE- CS
  Glyco_hydro_47 449 fnTeAHplkr 458
                     +nTeAHp++r
      EEA23095.1 577 LNTEAHPFRR 586
                     ********96 PP

>> DUF4368  Domain of unknown function (DUF4368)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   2.2e-05      0.19      11      38 ..     445     472 ..     437     474 .. 0.90

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 2.2e-05
     DUF4368  11 dvekFlalvrkytdieeLtpeilnelIe 38 
                 d +k+la v k  +i+ L+ e ++++I+
  EEA23095.1 445 DEKKWLAAVAKTAHINALDDETIHKFIK 472
                 5689***********************7 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (588 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       437  (0.0243739); expected 358.6 (0.02)
Passed bias filter:                      400  (0.0223102); expected 358.6 (0.02)
Passed Vit filter:                        37  (0.0020637); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.62u 0.30s 00:00:00.92 Elapsed: 00:00:00.47
# Mc/sec: 3747.66
//
Query:       EEA23096.1  [L=346]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
      2e-67  226.9   0.0    2.5e-67  226.5   0.0    1.1  1  Med20     TATA-binding related factor (TRF) of subunit 20 of 
  ------ inclusion threshold ------
       0.34   11.3   5.5       0.84   10.0   5.5    1.7  1  BES1_N    BES1/BZR1 plant transcription factor, N-terminal


Domain annotation for each model (and alignments):
>> Med20  TATA-binding related factor (TRF) of subunit 20 of Mediator complex
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  226.5   0.0   2.8e-71   2.5e-67       1     225 []       1     343 [.       1     343 [. 0.92

  Alignments for each domain:
  == domain 1  score: 226.5 bits;  conditional E-value: 2.8e-71
                 CH...HHHHHHCCS.............HHHHH-EEEEEEEEESSCCSECTTC..............BSEEEEEECTTTTSEEEEESSSE.......... CS
       Med20   1 Mpvtgvffipanpnaktalqtvtellrslealgatkvgrwalehklyrdtpsclpas....qrpaqpkylqfLslserpnsgfiiisqqpektgtnsqq 95 
                 Mp tgvffip++pna+  l  +te+lrs++ ++a ++grw lehkl+rdtpsclpas    +++ +++y+qfLs + +p+ gf++ s+ ++ +++++q+
  EEA23096.1   1 MPHTGVFFIPSSPNAPNILGPLTERLRSVYGDEAIPIGRWGLEHKLMRDTPSCLPASahapNPAPRARYVQFLSMTNHPKLGFVYASEDDDNETQTNQP 99 
                 99*******************************************************8855555555**********************9999988844 PP

                 .................EEEE-HSHHHHHHHCT.-SEEE-EEEEEEEE.BEESSEEEEEEEEECSS...S---EEEEEEE-S................. CS
       Med20  96 ........splvmttvsllsadslfqilleklqslWcqrqtvkvegggvYelgdfrvRvgdvfqtq...rvrGllvEieyrg................. 166
                         s ++m tv++ s+  +f++++++++++Wc+r+tv+v g + Y++gdfrvR+g+v+qtq   r rG+++E+e+rg                 
  EEA23096.1 100 itgrekteSGMIMSTVPIASSSEIFRHFVRCCEPIWCHRHTVTVTGTV-YDVGDFRVRLGEVRQTQpqaRPRGTIMEVEWRGpsmiadalspvssslgl 197
                 66666777************************************9887.************************************************** PP

                 ................................SS-CCCCHHHHHHCSCTT........T-TSCTT--...........-----EE-SSSS-........ CS
       Med20 167 .............................adpdaeyeaaaalireflskl........giegareai...........lvpdlgkeakealrk...... 211
                                              + +  eye+ + liref++k+        +                   l pd+g+e k+++ +      
  EEA23096.1 198 dktqdsgvlamdvdgdidsamktpyipteSEIQLEYEQISHLIREFWTKIyssndattN-------NkqlpttireaiLIPDVGRELKQRIAQrrqpgw 289
                 **************************************************766655441.......144455556656999999999999977999999 PP

                 .........................................CCHHHHHHHHHCG CS
       Med20 212 ........................................agvdlarQYmeilr 225
                                                         agvdlarQYme++r
  EEA23096.1 290 qerenrrrrkrreaialdrswggvsekqqqqqdeeeddmdAGVDLARQYMELFR 343
                 999999**********************************************97 PP

>> BES1_N  BES1/BZR1 plant transcription factor, N-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.0   5.5   9.4e-05      0.84       2      25 ..     283     305 ..     282     317 .. 0.78

  Alignments for each domain:
  == domain 1  score: 10.0 bits;  conditional E-value: 9.4e-05
      BES1_N   2 ggrkptwrErEnnkrRERrrraia 25 
                 ++r+p w+ErEn +rR R r aia
  EEA23096.1 283 QRRQPGWQERENRRRRKR-REAIA 305
                 789********9888866.56776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (346 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       684  (0.0381505); expected 358.6 (0.02)
Passed bias filter:                      413  (0.0230353); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.54u 0.29s 00:00:00.83 Elapsed: 00:00:00.47
# Mc/sec: 2223.37
//
Query:       EEA23097.1  [L=149]
Description: calmodulin [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    1.3e-41  137.0  11.6    7.8e-10   37.6   0.9    4.1  4  EF-hand_1        EF hand
    3.6e-36  123.4   5.3    3.9e-19   68.9   2.2    2.1  2  EF-hand_7        EF-hand domain pair
    1.9e-34  117.3  11.5    2.4e-15   56.1   0.6    4.0  4  EF-hand_8        EF-hand domain pair
    3.8e-30  101.2   8.5    7.1e-09   34.9   0.1    4.4  4  EF-hand_6        EF-hand domain
    6.8e-26   88.6   9.8    4.7e-06   25.9   0.1    4.2  4  EF-hand_5        EF hand
    1.4e-16   60.5   0.4    2.3e-09   37.4   0.0    2.1  2  EF-hand_9        EF-hand domain
    6.8e-10   38.8   1.6    0.00078   19.4   0.3    2.1  2  EF-hand_4        Cytoskeletal-regulatory complex EF hand
    5.9e-09   36.2   0.2     0.0016   18.7   0.1    2.1  2  SPARC_Ca_bdg     Secreted protein acidic and rich in cysteine
      1e-06   28.6   0.1      0.008   16.2   0.0    3.0  3  UPF0154          Uncharacterised protein family (UPF0154)
    6.4e-06   26.2   1.6    2.3e-05   24.4   0.2    2.3  2  EFhand_Ca_insen  Ca2+ insensitive EF hand
    9.4e-05   23.2   0.2     0.0025   18.6   0.1    2.0  2  EF-hand_11       EF-hand domain
    0.00013   21.9   0.3       0.35   10.8   0.0    2.2  2  TerB             Tellurite resistance protein TerB
    0.00059   19.8   1.6       0.52   10.2   0.0    3.5  4  Caleosin         Caleosin related protein
    0.00062   20.1   0.7       0.66   10.3   0.1    2.6  3  RNA_pol_Rpb4     RNA polymerase Rpb4
     0.0053   16.9   7.0       0.38   11.0   0.8    2.9  3  Dockerin_1       Dockerin type I domain
     0.0057   15.3   0.0     0.0058   15.2   0.0    1.0  1  DUF5580          Family of unknown function (DUF5580)
     0.0084   16.0   0.7       0.32   10.9   0.1    2.2  2  SurA_N_2         SurA N-terminal domain
  ------ inclusion threshold ------
      0.012   16.0   0.5        6.2    7.2   0.1    2.4  2  EF-hand_14       EF-hand domain
      0.023   14.9   0.0       0.18   12.0   0.0    2.5  2  Poly_export      Polysaccharide biosynthesis/export protein
      0.058   13.9   0.1        8.5    6.9   0.0    3.0  3  RuvA_C           RuvA, C-terminal domain
      0.061   12.5   0.1          1    8.5   0.1    2.1  2  dCache_2         Cache domain
      0.061   13.5   0.3       0.91    9.7   0.0    2.3  2  MotA_activ       Transcription factor MotA, activation domain
      0.092   13.2   0.0        8.7    6.9   0.0    2.1  2  DUF4497          Protein of unknown function (DUF4497)
       0.11   12.7   1.3       0.72   10.0   0.2    2.1  2  RloB             RloB-like protein
       0.16   12.1   0.5         21    5.3   0.1    2.3  2  DUF5132          Protein of unknown function (DUF5132)


Domain annotation for each model (and alignments):
>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.4   0.1   5.4e-12   3.9e-09       1      29 []      12      40 ..      12      40 .. 0.95
   2 !   33.9   0.2   1.7e-11   1.2e-08       1      28 [.      48      75 ..      48      76 .. 0.95
   3 !   35.9   0.0   3.8e-12   2.7e-09       1      28 [.      85     112 ..      85     113 .. 0.96
   4 !   37.6   0.9   1.1e-12   7.8e-10       1      27 [.     121     147 ..     121     149 .] 0.95

  Alignments for each domain:
  == domain 1  score: 35.4 bits;  conditional E-value: 5.4e-12
                HHHHHHHHHTTTSSSEEEHHHHHHHHHHH CS
   EF-hand_1  1 elkeiFrefDkDgdGkIdfeEfkellkkl 29
                e ke+F++fDkDgdG+I+ +E+ +++++l
  EEA23097.1 12 EYKEAFSLFDKDGDGQITTKELGTVMRSL 40
                689***********************986 PP

  == domain 2  score: 33.9 bits;  conditional E-value: 1.7e-11
                HHHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1  1 elkeiFrefDkDgdGkIdfeEfkellkk 28
                el+++++e+D D++G+Idf Ef++++++
  EEA23097.1 48 ELQDMINEVDADNNGTIDFPEFLTMMAR 75
                799***********************86 PP

  == domain 3  score: 35.9 bits;  conditional E-value: 3.8e-12
                 HHHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1   1 elkeiFrefDkDgdGkIdfeEfkellkk 28 
                 e++e+F++fD+D++G+I+  E+++++++
  EEA23097.1  85 EIREAFKVFDRDNNGFISAAELRHVMTS 112
                 79************************97 PP

  == domain 4  score: 37.6 bits;  conditional E-value: 1.1e-12
                 HHHHHHHHHTTTSSSEEEHHHHHHHHH CS
   EF-hand_1   1 elkeiFrefDkDgdGkIdfeEfkellk 27 
                 e++e++re+D+DgdG+Id++Ef++l++
  EEA23097.1 121 EVDEMIREADQDGDGRIDYNEFVQLMM 147
                 79************************8 PP

>> EF-hand_7  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.9   0.1     6e-18   4.3e-15       4      70 ..      13      73 ..      10      74 .. 0.95
   2 !   68.9   2.2   5.4e-22   3.9e-19       1      70 [.      83     146 ..      83     147 .. 0.97

  Alignments for each domain:
  == domain 1  score: 55.9 bits;  conditional E-value: 6e-18
   EF-hand_7  4 lkeaFkelDtdgdgyldkeellrllrkifqgagegsklsdeelellfkefDtdkdGvisfdEFlkly 70
                 keaF ++D+dgdg ++  el  ++r      + g ++s+ el+++++e+D d++G+i+f EFl+++
  EEA23097.1 13 YKEAFSLFDKDGDGQITTKELGTVMR------SLGQNPSESELQDMINEVDADNNGTIDFPEFLTMM 73
                689*******************9999......999999***************************99 PP

  == domain 2  score: 68.9 bits;  conditional E-value: 5.4e-22
   EF-hand_7   1 eeklkeaFkelDtdgdgyldkeellrllrkifqgagegsklsdeelellfkefDtdkdGvisfdEFlkly 70 
                 ee+++eaFk +D+d++g+++ +el+++++      + g+kl+d+e++++++e D+d+dG+i+++EF++l+
  EEA23097.1  83 EEEIREAFKVFDRDNNGFISAAELRHVMT------SIGEKLTDDEVDEMIREADQDGDGRIDYNEFVQLM 146
                 689**************************......9********************************99 PP

>> EF-hand_8  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.7   0.2    0.0005      0.36      30      47 ..      15      32 ..       3      33 .. 0.85
   2 !   53.1   0.1   2.8e-17     2e-14       2      54 ..      25      75 ..      24      76 .. 0.97
   3 !   18.7   0.1   1.6e-06    0.0012      24      46 ..      82     104 ..      75     105 .. 0.88
   4 !   56.1   0.6   3.3e-18   2.4e-15       2      52 ..      98     146 ..      98     148 .. 0.96

  Alignments for each domain:
  == domain 1  score: 10.7 bits;  conditional E-value: 0.0005
   EF-hand_8 30 ilfrefDtdgdGkisfeE 47
                + f++fD dgdG i+ +E
  EEA23097.1 15 EAFSLFDKDGDGQITTKE 32
                579***********9887 PP

  == domain 2  score: 53.1 bits;  conditional E-value: 2.8e-17
   EF-hand_8  2 kgkItreelrrilrilglkkglseeevdilfrefDtdgdGkisfeEFcvller 54
                +g+It+ el + +r+lg++   se+e++++++e+D d++G+i+f EF+ +++r
  EEA23097.1 25 DGQITTKELGTVMRSLGQN--PSESELQDMINEVDADNNGTIDFPEFLTMMAR 75
                8******************..******************************97 PP

  == domain 3  score: 18.7 bits;  conditional E-value: 1.6e-06
   EF-hand_8  24 seeevdilfrefDtdgdGkisfe 46 
                 seee+++ f+ fD+d++G is  
  EEA23097.1  82 SEEEIREAFKVFDRDNNGFISAA 104
                 89****************99965 PP

  == domain 4  score: 56.1 bits;  conditional E-value: 3.3e-18
   EF-hand_8   2 kgkItreelrrilrilglkkglseeevdilfrefDtdgdGkisfeEFcvll 52 
                 +g I+ +elr+ ++++g k  l+++evd+++re+D+dgdG+i+++EF++l+
  EEA23097.1  98 NGFISAAELRHVMTSIGEK--LTDDEVDEMIREADQDGDGRIDYNEFVQLM 146
                 599**********888*99..****************************98 PP

>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.9   0.1   9.9e-12   7.1e-09       2      31 .]      13      41 ..      12      41 .. 0.94
   2 !   15.2   0.1     2e-05     0.014       2      27 ..      49      74 ..      46      80 .. 0.87
   3 !   34.7   0.0   1.1e-11     8e-09       1      31 []      85     114 ..      85     114 .. 0.94
   4 !   19.1   0.4   1.1e-06   0.00082       7      27 ..     127     147 ..     116     149 .] 0.86

  Alignments for each domain:
  == domain 1  score: 34.9 bits;  conditional E-value: 9.9e-12
   EF-hand_6  2 lreaFklfDkdgdGkidaeElrkalrkalg 31
                 +eaF lfDkdgdG+i+++El  ++r +lg
  EEA23097.1 13 YKEAFSLFDKDGDGQITTKELGTVMR-SLG 41
                689***********************.887 PP

  == domain 2  score: 15.2 bits;  conditional E-value: 2e-05
   EF-hand_6  2 lreaFklfDkdgdGkidaeElrkalr 27
                l++  ++ D d++G+id+ E+  ++ 
  EEA23097.1 49 LQDMINEVDADNNGTIDFPEFLTMMA 74
                66777889**************9986 PP

  == domain 3  score: 34.7 bits;  conditional E-value: 1.1e-11
   EF-hand_6   1 elreaFklfDkdgdGkidaeElrkalrkalg 31 
                 e+reaFk fD+d++G+i+a+Elr++++ + g
  EEA23097.1  85 EIREAFKVFDRDNNGFISAAELRHVMT-SIG 114
                 79************************9.665 PP

  == domain 4  score: 19.1 bits;  conditional E-value: 1.1e-06
   EF-hand_6   7 klfDkdgdGkidaeElrkalr 27 
                 ++ D+dgdG id++E+++++ 
  EEA23097.1 127 READQDGDGRIDYNEFVQLMM 147
                 678**************9886 PP

>> EF-hand_5  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.9   0.1   6.5e-09   4.7e-06       3      25 .]      15      37 ..      14      37 .. 0.92
   2 !   20.2   0.1   3.9e-07   0.00028       1      25 []      49      73 ..      49      73 .. 0.94
   3 !   24.8   0.0   1.4e-08   9.9e-06       1      25 []      86     110 ..      86     110 .. 0.91
   4 !   21.9   0.4   1.1e-07   8.2e-05       3      25 .]     124     146 ..     122     147 .. 0.87

  Alignments for each domain:
  == domain 1  score: 25.9 bits;  conditional E-value: 6.5e-09
                HHHHHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5  3 dtFqaiDlNgDGkIskeELktlv 25
                ++F+ +D++gDG+I+  EL t++
  EEA23097.1 15 EAFSLFDKDGDGQITTKELGTVM 37
                57******************987 PP

  == domain 2  score: 20.2 bits;  conditional E-value: 3.9e-07
                HHHHHHHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5  1 lkdtFqaiDlNgDGkIskeELktlv 25
                l+d+ +++D+++ G+I++ E+ t++
  EEA23097.1 49 LQDMINEVDADNNGTIDFPEFLTMM 73
                7899*****************9986 PP

  == domain 3  score: 24.8 bits;  conditional E-value: 1.4e-08
                 HHHHHHHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5   1 lkdtFqaiDlNgDGkIskeELktlv 25 
                 ++++F+ +D ++ G+Is+ EL+ ++
  EEA23097.1  86 IREAFKVFDRDNNGFISAAELRHVM 110
                 5778*****************9876 PP

  == domain 4  score: 21.9 bits;  conditional E-value: 1.1e-07
                 HHHHHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5   3 dtFqaiDlNgDGkIskeELktlv 25 
                 ++ +++D +gDG+I+  E+ +l+
  EEA23097.1 124 EMIREADQDGDGRIDYNEFVQLM 146
                 57899**************9875 PP

>> EF-hand_9  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   37.4   0.0   3.2e-12   2.3e-09       3      64 ..      16      75 ..      14      77 .. 0.96
   2 !   21.6   0.1   2.8e-07    0.0002       3      64 ..      89     148 ..      87     149 .] 0.95

  Alignments for each domain:
  == domain 1  score: 37.4 bits;  conditional E-value: 3.2e-12
   EF-hand_9  3 vFevcDtqktGrVpvsrlidyLravtaqdpeeseLeelakelDPdgedasvdldtflrvmre 64
                 F+++D +  G+++ ++l +++r  ++ +p+eseL++  +e+D d++ +++d+  fl++m +
  EEA23097.1 16 AFSLFDKDGDGQITTKELGTVMRSLGQ-NPSESELQDMINEVDADNN-GTIDFPEFLTMMAR 75
                6**************************.*******************.************76 PP

  == domain 2  score: 21.6 bits;  conditional E-value: 2.8e-07
   EF-hand_9   3 vFevcDtqktGrVpvsrlidyLravtaqdpeeseLeelakelDPdgedasvdldtflrvmre 64 
                  F+v+D++  G +  ++l  ++   ++ + ++ e++e  +e+D dg  + +d + f + m++
  EEA23097.1  89 AFKVFDRDNNGFISAAELRHVMTSIGE-KLTDDEVDEMIREADQDGD-GRIDYNEFVQLMMQ 148
                 5*************************9.88999************99.************97 PP

>> EF-hand_4  Cytoskeletal-regulatory complex EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.0   0.1   1.4e-06     0.001       4      69 ..       5      73 ..       1      81 [. 0.84
   2 !   19.4   0.3   1.1e-06   0.00078       7      69 ..      84     146 ..      77     148 .. 0.81

  Alignments for each domain:
  == domain 1  score: 19.0 bits;  conditional E-value: 1.4e-06
   EF-hand_4  4 leeleikkyweifsgl.kpednkltgdkvapvlkn..skleedklekiwdladidedgkldfeefciam 69
                l e ++ +y e fs   k+ d ++t +++ +v+++   + +e++l+ + +  d d++g++df ef  +m
  EEA23097.1  5 LTEEQVSEYKEAFSLFdKDGDGQITTKELGTVMRSlgQNPSESELQDMINEVDADNNGTIDFPEFLTMM 73
                6788899999999987256799***********98324567899*********************9888 PP

  == domain 2  score: 19.4 bits;  conditional E-value: 1.1e-06
   EF-hand_4   7 leikkyweifsglkpednkltgdkvapvlkn..skleedklekiwdladidedgkldfeefciam 69 
                  ei++ +++f   ++++  ++  ++  v+ +   kl++d+++++   ad d dg++d++ef+  m
  EEA23097.1  84 EEIREAFKVFD--RDNNGFISAAELRHVMTSigEKLTDDEVDEMIREADQDGDGRIDYNEFVQLM 146
                 56666667775..3567789999999999864379**************************9776 PP

>> SPARC_Ca_bdg  Secreted protein acidic and rich in cysteine Ca binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.0   1.6e-05     0.011      59     111 ..      16      70 ..       2      73 .. 0.86
   2 !   18.7   0.1   2.3e-06    0.0016      51     111 ..      81     143 ..      71     145 .. 0.85

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 1.6e-05
  SPARC_Ca_bdg  59 kFsklDtnsdkvlsksELaplrapl..vklehCikpflescDadkdkkislkEwc 111
                    Fs +D++ d+ ++++EL  +  +l   + e+  + ++++ Dad++++i+  E+ 
    EEA23097.1  16 AFSLFDKDGDGQITTKELGTVMRSLgqNPSESELQDMINEVDADNNGTIDFPEFL 70 
                   6999*****************999944567999*******************996 PP

  == domain 2  score: 18.7 bits;  conditional E-value: 2.3e-06
  SPARC_Ca_bdg  51 eckepvawkFsklDtnsdkvlsksELaplrapl..vklehCikpflescDadkdkkislkEwc 111
                     +e+++  F+ +D ++++++s +EL+++ +++    ++  ++++++++D+d d++i+ +E++
    EEA23097.1  81 DSEEEIREAFKVFDRDNNGFISAAELRHVMTSIgeKLTDDEVDEMIREADQDGDGRIDYNEFV 143
                   456788889********************9998333468899*******************97 PP

>> UPF0154  Uncharacterised protein family (UPF0154)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   1.1e-05     0.008      29      58 ..      27      56 ..      24      58 .. 0.91
   2 ?   -0.2   0.0       1.5   1.1e+03      36      54 ..      71      89 ..      67      95 .. 0.72
   3 !    8.7   0.0    0.0024       1.7      26      57 ..      97     128 ..      89     131 .. 0.89

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.1e-05
     UPF0154 29 pinekmirammkqmGrkPSekqikqvmrsm 58
                +i+ k + + m++ G++PSe+ ++ +++++
  EEA23097.1 27 QITTKELGTVMRSLGQNPSESELQDMINEV 56
                688999999*****************9987 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 1.5
     UPF0154 36 rammkqmGrkPSekqikqv 54
                 +m+++m  + Se  i++ 
  EEA23097.1 71 TMMARKMKDTDSEEEIREA 89
                5677888777788777765 PP

  == domain 3  score: 8.7 bits;  conditional E-value: 0.0024
     UPF0154  26 enPpinekmirammkqmGrkPSekqikqvmrs 57 
                 +n  i++  +r  m + G k++   + +++r+
  EEA23097.1  97 NNGFISAAELRHVMTSIGEKLTDDEVDEMIRE 128
                 577899***********************986 PP

>> EFhand_Ca_insen  Ca2+ insensitive EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.7   0.1      0.77   5.5e+02      10      28 ..      15      34 ..       3      74 .. 0.48
   2 !   24.4   0.2   3.2e-08   2.3e-05       1      69 []      79     148 ..      79     148 .. 0.83

  Alignments for each domain:
  == domain 1  score: 0.7 bits;  conditional E-value: 0.77
                     CHHHHH.CTTSSSEEHHHHH CS
  EFhand_Ca_insen 10 eaFral.aggKpYvTeedLr 28
                     eaF    ++g   +T ++L 
       EEA23097.1 15 EAFSLFdKDGDGQITTKELG 34
                     56666666666666666663 PP

  == domain 2  score: 24.4 bits;  conditional E-value: 3.2e-08
                      G-STHHHHHCHHHHH.CTTSSSEEHHHHHHH-TT..CHH.HHHHCCSEEE-STT..S-TTEEECCCHTTTTTT CS
  EFhand_Ca_insen   1 dvdsaeqveeaFral.aggKpYvTeedLrrellp..eqa.eylierMpeysgpegdavekayDYvsFlealfa 69 
                      d+ds e+++eaF+    ++  ++ + +Lr+ ++   e+  +  +++M +  +++     +  DY++F++ +++
       EEA23097.1  79 DTDSEEEIREAFKVFdRDNNGFISAAELRHVMTSigEKLtDDEVDEMIREADQD---GDGRIDYNEFVQLMMQ 148
                      89*************888889********9887533555588888888888766...56789*******9986 PP

>> EF-hand_11  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.7   0.0      0.15   1.1e+02      33      84 ..      24      75 ..       8      83 .. 0.74
   2 !   18.6   0.1   3.6e-06    0.0025      20      80 ..      84     144 ..      72     149 .] 0.87

  Alignments for each domain:
  == domain 1  score: 3.7 bits;  conditional E-value: 0.15
                -SSEE-HHHHHHHHHHHT----HHHHHHHHHTS-B-TTS-EEHHHHHHHHCS CS
  EF-hand_11 33 ksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdflsklsi 84
                    ++ +e+ ++     q  ++ +++ + +e+  + +g + +++fl+ ++ 
  EEA23097.1 24 GDGQITTKELGTVMRSLGQNPSESELQDMINEVDADNNGTIDFPEFLTMMAR 75
                55556666666666666666677788889999**************998765 PP

  == domain 2  score: 18.6 bits;  conditional E-value: 3.6e-06
                 HHHHHHHHHH-TT-SSEE-HHHHHHHHHHHT----HHHHHHHHHTS-B-TTS-EEHHHHHH CS
  EF-hand_11  20 haivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdfls 80 
                   i + f+ fd  +   +s  e+r + t   + ltd++ d +  e   +  gr+ y++f+ 
  EEA23097.1  84 EEIREAFKVFDRDNNGFISAAELRHVMTSIGEKLTDDEVDEMIREADQDGDGRIDYNEFVQ 144
                 568889*****************************************************86 PP

>> TerB  Tellurite resistance protein TerB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.8   0.0   0.00049      0.35      41     108 ..      25      90 ..      23      98 .. 0.87
   2 !    9.5   0.1    0.0013       0.9      44      93 ..     101     148 ..      96     149 .] 0.89

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00049
        TerB  41 DgqvsesErqafrellksrfglspeeakallelfeeaeeeavdleqftralkrklspeqrraliealw 108
                 Dgq++ +E   +++ l ++ +  + e+++ + + ++  + ++d+ +f   ++rk+++ + ++ i+  +
  EEA23097.1  25 DGQITTKELGTVMRSLGQNPS--ESELQDMINEVDADNNGTIDFPEFLTMMARKMKDTDSEEEIREAF 90 
                 9***************66665..99*****************************99777666555555 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.0013
        TerB  44 vsesErqafrellksrfglspeeakallelfeeaeeeavdleqftralkr 93 
                 +s++E +++++ +    +l+++e+++ ++++++  +  +d+ +f++ + +
  EEA23097.1 101 ISAAELRHVMTSI--GEKLTDDEVDEMIREADQDGDGRIDYNEFVQLMMQ 148
                 7888999999999..78889************************998876 PP

>> Caleosin  Caleosin related protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.2   0.0   0.00072      0.52      10      41 ..      17      48 ..       8      56 .. 0.83
   2 ?    3.1   0.1      0.11        81      93     127 ..      47      81 ..      43      90 .. 0.84
   3 ?    4.8   0.0     0.032        23      10      34 ..      90     114 ..      82     119 .. 0.76
   4 ?   -0.4   0.0       1.3   9.5e+02      94     118 ..     121     145 ..     115     149 .] 0.54

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.00072
    Caleosin 10 vaFfDrdkdGiiypldtyrgfralgfnvllsl 41
                ++ fD+d dG i+  +  + +r+lg n   s 
  EEA23097.1 17 FSLFDKDGDGQITTKELGTVMRSLGQNPSESE 48
                578**********************9977665 PP

  == domain 2  score: 3.1 bits;  conditional E-value: 0.11
    Caleosin  93 qkfeeifskyakekkdaltlkevlellkgqrealD 127
                 ++++++ ++ ++++++++ + e+l+++ ++++ +D
  EEA23097.1  47 SELQDMINEVDADNNGTIDFPEFLTMMARKMKDTD 81 
                 67888999999999999999999999999888777 PP

  == domain 3  score: 4.8 bits;  conditional E-value: 0.032
    Caleosin  10 vaFfDrdkdGiiypldtyrgfralg 34 
                 ++ fDrd++G+i   +  + + ++g
  EEA23097.1  90 FKVFDRDNNGFISAAELRHVMTSIG 114
                 5679999999999988877777666 PP

  == domain 4  score: -0.4 bits;  conditional E-value: 1.3
    Caleosin  94 kfeeifskyakekkdaltlkevlel 118
                 + +e+ ++ +++ ++ + ++e+++l
  EEA23097.1 121 EVDEMIREADQDGDGRIDYNEFVQL 145
                 4455555555555555555555555 PP

>> RNA_pol_Rpb4  RNA polymerase Rpb4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    7.4   0.0    0.0074       5.3      92     120 ..      29      57 ..      28      58 .. 0.93
   2 ?   -1.8   0.0       5.3   3.8e+03      50      70 ..      71      91 ..      63      99 .. 0.59
   3 !   10.3   0.1   0.00091      0.66      91     118 ..     101     128 ..      96     131 .. 0.91

  Alignments for each domain:
  == domain 1  score: 7.4 bits;  conditional E-value: 0.0074
                   SHHHHHHHSTTGTTTSTSHHHHHHHHHHH CS
  RNA_pol_Rpb4  92 savelktlieeleerfedeqleeiLdelk 120
                   ++ el t++ +l +  ++++l+++++e+ 
    EEA23097.1  29 TTKELGTVMRSLGQNPSESELQDMINEVD 57 
                   6789**********************985 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 5.3
                  HHHHCTHHTTSSHHHHHHHHH CS
  RNA_pol_Rpb4 50 eyltnkfsrlkneekfnelve 70
                  +++ +k + +++ee+++e ++
    EEA23097.1 71 TMMARKMKDTDSEEEIREAFK 91
                  444444555555666665554 PP

  == domain 3  score: 10.3 bits;  conditional E-value: 0.00091
                   SSHHHHHHHSTTGTTTSTSHHHHHHHHH CS
  RNA_pol_Rpb4  91 esavelktlieeleerfedeqleeiLde 118
                   +sa+el+ ++ ++ e+++d++++e++ e
    EEA23097.1 101 ISAAELRHVMTSIGEKLTDDEVDEMIRE 128
                   689**********************986 PP

>> Dockerin_1  Dockerin type I domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    8.0   0.7    0.0046       3.3       2      50 ..      20      69 ..      19      75 .. 0.82
   2 ?    2.8   0.4      0.19   1.3e+02      17      53 ..      72     109 ..      57     114 .. 0.69
   3 !   11.0   0.8   0.00053      0.38       3      53 ..      94     145 ..      92     148 .. 0.83

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.0046
                TETTSSSC-SHHHHHHHHHHCT.SSEBTTSCCCHGGGSTT-SSCESHHHH CS
  Dockerin_1  2 gDVNgDgkVnalDalliinyln.qregqssssngkaaDvNgDGrvnalDa 50
                +D +gDg+++   +  + + l  + ++++ + + +  D +++G+++   +
  EEA23097.1 20 FDKDGDGQITTKELGTVMRSLGqNPSESELQDMINEVDADNNGTIDFPEF 69
                6889*****************9666677778889999******9986555 PP

  == domain 2  score: 2.8 bits;  conditional E-value: 0.19
                 HHHHHCT.SSEBTTSCCCHGGGSTT-SSCESHHHHHHH CS
  Dockerin_1  17 liinyln.qregqssssngkaaDvNgDGrvnalDallv 53 
                 ++ + +  ++++++  +  k +D +++G ++a  +  v
  EEA23097.1  72 MMARKMKdTDSEEEIREAFKVFDRDNNGFISAAELRHV 109
                 55555665555566666677899999999999877655 PP

  == domain 3  score: 11.0 bits;  conditional E-value: 0.00053
                 ETTSSSC-SHHHHHHHHHHCT.SSEBTTSCCCHGGGSTT-SSCESHHHHHHH CS
  Dockerin_1   3 DVNgDgkVnalDalliinyln.qregqssssngkaaDvNgDGrvnalDallv 53 
                 D +++g ++a  +  +   +  + ++++ +++ + aD +gDGr++   + ++
  EEA23097.1  94 DRDNNGFISAAELRHVMTSIGeKLTDDEVDEMIREADQDGDGRIDYNEFVQL 145
                 778888888888888888888777899999***************9888877 PP

>> DUF5580  Family of unknown function (DUF5580)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0     8e-06    0.0058     284     386 ..      46     147 ..       8     149 .] 0.80

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 8e-06
     DUF5580 284 ssdekstapqdsssesevnkslleiLkmalktakgklnlenLnlsFrkeDrsfsGlLpppkvraiCgkhglyltlslletllnhqdlgyqdeikWqnfv 382
                 +s+ +  + ++ + +++ + ++ e L m  +++k+  + e+++ +F+  Dr   G+++ +++r +    g  lt   ++ ++   d    + i +++fv
  EEA23097.1  46 ESELQ-DMINEVDADNNGTIDFPEFLTMMARKMKDTDSEEEIREAFKVFDRDNNGFISAAELRHVMTSIGEKLTDDEVDEMIREADQDGDGRIDYNEFV 143
                 33222.223334444445568889999999999999999************************************************************ PP

     DUF5580 383 elLs 386
                 +l+ 
  EEA23097.1 144 QLMM 147
                 *975 PP

>> SurA_N_2  SurA N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.0     0.049        35      97     137 ..      31      65 ..      25      73 .. 0.75
   2 !   10.9   0.1   0.00044      0.32      87     144 ..      94     145 ..      60     146 .. 0.77

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.049
    SurA_N_2  97 klleqeaeklGltvsdeelqdaiqgnpaikqsFqpetGkFd 137
                 k l   +++lG + s++elqd+i++  a      +++G +d
  EEA23097.1  31 KELGTVMRSLGQNPSESELQDMINEVDA------DNNGTID 65 
                 556677899**************99776......4666666 PP

  == domain 2  score: 10.9 bits;  conditional E-value: 0.00044
    SurA_N_2  87 eqvldqlvseklleqeaeklGltvsdeelqdaiqgnpaikqsFqpetGkFdkeklkqf 144
                 ++  + ++s + l++ + ++G + +d+e++++i++  +      + +G++d +++ q+
  EEA23097.1  94 DRDNNGFISAAELRHVMTSIGEKLTDDEVDEMIREADQ------DGDGRIDYNEFVQL 145
                 555578899999999********************999......79999999999886 PP

>> EF-hand_14  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   0.0    0.0093       6.7       6      47 ..      17      58 ..      14      84 .. 0.90
   2 ?    7.2   0.1    0.0087       6.2       6      52 ..      90     136 ..      83     149 .] 0.84

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.0093
  EF-hand_14  6 fdlfkdeetdklsvakllkaLaetGirkdDpRLkellkklkk 47
                f lf++++++++  ++l +++++ G + +   L+++++++  
  EEA23097.1 17 FSLFDKDGDGQITTKELGTVMRSLGQNPSESELQDMINEVDA 58
                899********************************9999875 PP

  == domain 2  score: 7.2 bits;  conditional E-value: 0.0087
  EF-hand_14   6 fdlfkdeetdklsvakllkaLaetGirkdDpRLkellkklkkvekek 52 
                 f++f++++++ +s a+l +++ + G + +D  ++e++++  +  + +
  EEA23097.1  90 FKVFDRDNNGFISAAELRHVMTSIGEKLTDDEVDEMIREADQDGDGR 136
                 899999******************************99877766555 PP

>> Poly_export  Polysaccharide biosynthesis/export protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.0   0.0   0.00026      0.18      29      70 ..      51      92 ..      11     102 .. 0.85
   2 ?   -1.4   0.0       3.9   2.8e+03      55      67 ..     117     129 ..     115     140 .. 0.75

  Alignments for each domain:
  == domain 1  score: 12.0 bits;  conditional E-value: 0.00026
  Poly_export 29 qalqgylVdpdGtIslPllGkikvaGltveelreeieeklsk 70
                 + ++++  d++GtI++P   ++ +  +  ++ +eei+e+++ 
   EEA23097.1 51 DMINEVDADNNGTIDFPEFLTMMARKMKDTDSEEEIREAFKV 92
                 45667778999***************************9954 PP

  == domain 2  score: -1.4 bits;  conditional E-value: 3.9
  Poly_export  55 ltveelreeieek 67 
                  lt +e+ e+i+e+
   EEA23097.1 117 LTDDEVDEMIREA 129
                  6778888888875 PP

>> RuvA_C  RuvA, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.3   0.0       0.7     5e+02      16      30 ..      45      60 ..      30      65 .. 0.81
   2 ?    1.7   0.0       0.5   3.6e+02      31      44 ..      78      91 ..      70      93 .. 0.85
   3 ?    6.9   0.0     0.012       8.5      17      42 ..     103     129 ..     102     129 .. 0.81

  Alignments for each domain:
  == domain 1  score: 1.3 bits;  conditional E-value: 0.7
                -HHHHHHHHHHHHC.- CS
      RuvA_C 16 kekeaekAvakvla.n 30
                +e e + ++++v+a n
  EEA23097.1 45 SESELQDMINEVDAdN 60
                5789999999998743 PP

  == domain 2  score: 1.7 bits;  conditional E-value: 0.5
                TTS-HHHHHHHHHC CS
      RuvA_C 31 pgasveelIraALk 44
                +++++ee Ir+A k
  EEA23097.1 78 KDTDSEEEIREAFK 91
                67899999***987 PP

  == domain 3  score: 6.9 bits;  conditional E-value: 0.012
                 HHHHHHHHHHHHC.-TTS-HHHHHHHH CS
      RuvA_C  17 ekeaekAvakvla.npgasveelIraA 42 
                 ++e +++ +++ +  +++ v+e+Ir+A
  EEA23097.1 103 AAELRHVMTSIGEkLTDDEVDEMIREA 129
                 6888999999976666666*******9 PP

>> dCache_2  Cache domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.1   0.0      0.13        91     235     259 ..      42      66 ..       4      70 .. 0.63
   2 ?    8.5   0.1    0.0014         1     188     260 ..      81     140 ..      68     142 .. 0.70

  Alignments for each domain:
  == domain 1  score: 2.1 bits;  conditional E-value: 0.13
    dCache_2 235 kdkkgkllqelleaakkkgegfveY 259
                 +++++++lq++++  +++++g++++
  EEA23097.1  42 QNPSESELQDMINEVDADNNGTIDF 66 
                 3344444888888888888888876 PP

  == domain 2  score: 8.5 bits;  conditional E-value: 0.0014
    dCache_2 188 elkqellktlksirygnngyifiydtdgniilhplkkelngknllevkdkkgkl.lqelleaakkkgegfveYk 260
                 + ++e+++ +k +  +nng+i +     +++                 +k  ++ + e+++ a+++g+g+++Y+
  EEA23097.1  81 DSEEEIREAFKVFDRDNNGFISAAELRHVMTSIG--------------EKLTDDeVDEMIREADQDGDGRIDYN 140
                 4446777777777777777777777777666666..............33333469*****************7 PP

>> MotA_activ  Transcription factor MotA, activation domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.4   0.0      0.48   3.4e+02      60      75 ..      19      34 ..      13      42 .. 0.83
   2 ?    9.7   0.0    0.0013      0.91      28      69 ..      98     137 ..      71     147 .. 0.85

  Alignments for each domain:
  == domain 1  score: 1.4 bits;  conditional E-value: 0.48
                SEEEETTEEEE-HHHH CS
  MotA_activ 60 lveksgdgliitgeaq 75
                l +k gdg i t e  
  EEA23097.1 19 LFDKDGDGQITTKELG 34
                789*******999865 PP

  == domain 2  score: 9.7 bits;  conditional E-value: 0.0013
                 STTB-HHHHHHT-TTS-HHHHHHHHHHHHHTTSEEEETTEEE CS
  MotA_activ  28 kdfitaaevrevhpdlgnavvnsnigvlikkglveksgdgli 69 
                 + fi+aae+r v   +g+ + + ++  +i+    ++ gdg i
  EEA23097.1  98 NGFISAAELRHVMTSIGEKLTDDEVDEMIREA--DQDGDGRI 137
                 67***********************9999975..67788876 PP

>> DUF4497  Protein of unknown function (DUF4497)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.5   0.0     0.068        49      72     104 ..      10      43 ..       2      43 .. 0.86
   2 ?    6.9   0.0     0.012       8.7      56     106 ..      67     118 ..      46     119 .. 0.84

  Alignments for each domain:
  == domain 1  score: 4.5 bits;  conditional E-value: 0.068
     DUF4497  72 sktikgtfpLkdedgq.tvGeislylRlsclGks 104
                 +   k  f L+d+dg+ ++ + +l + + +lG++
  EEA23097.1  10 VSEYKEAFSLFDKDGDgQITTKELGTVMRSLGQN 43 
                 5678999*********999999999999999985 PP

  == domain 2  score: 6.9 bits;  conditional E-value: 0.012
     DUF4497  56 nklikevkekkknepvsktikgtfpLkdedgq.tvGeislylRlsclGksii 106
                  +++ ++++k+k + + + i+  f+++d d++  +   +l   +++ G++++
  EEA23097.1  67 PEFLTMMARKMKDTDSEEEIREAFKVFDRDNNgFISAAELRHVMTSIGEKLT 118
                 4556667777888889999*************99*************99986 PP

>> RloB  RloB-like protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.9   0.0      0.31   2.2e+02      59      76 ..       9      27 ..       2      39 .. 0.77
   2 ?   10.0   0.2     0.001      0.72      48      81 ..      53     105 ..      27     119 .. 0.69

  Alignments for each domain:
  == domain 1  score: 1.9 bits;  conditional E-value: 0.31
        RloB 59 yeeeydkvwcVfDrD.ksk 76
                + +ey++ + +fD+D + +
  EEA23097.1  9 QVSEYKEAFSLFDKDgDGQ 27
                56799**********5444 PP

  == domain 2  score: 10.0 bits;  conditional E-value: 0.001
        RloB  48 vekaiel..................kkekyeeeydkvwcVfDrD.kskdfeae 81 
                 ++++++                   k+ ++eee+ + + VfDrD + + + ae
  EEA23097.1  53 INEVDADnngtidfpefltmmarkmKDTDSEEEIREAFKVFDRDnNGFISAAE 105
                 444444455555555555555666688999**************776666554 PP

>> DUF5132  Protein of unknown function (DUF5132)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.3   0.1     0.029        21      30      40 ..      48      58 ..      46      61 .. 0.91
   2 ?    4.9   0.0      0.04        29      13      33 ..      99     119 ..      97     128 .. 0.89

  Alignments for each domain:
  == domain 1  score: 5.3 bits;  conditional E-value: 0.029
     DUF5132 30 eLeDlvAEvkA 40
                eL+D++ Ev A
  EEA23097.1 48 ELQDMINEVDA 58
                8********99 PP

  == domain 2  score: 4.9 bits;  conditional E-value: 0.04
     DUF5132  13 giglyeearkaaaevGEeLeD 33 
                 g + ++e+r  ++ +GE+L D
  EEA23097.1  99 GFISAAELRHVMTSIGEKLTD 119
                 5566899************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (149 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       893  (0.0498076); expected 358.6 (0.02)
Passed bias filter:                      610  (0.0340231); expected 358.6 (0.02)
Passed Vit filter:                        71  (0.00396006); expected 17.9 (0.001)
Passed Fwd filter:                        25  (0.00139439); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              25  [number of targets reported over threshold]
# CPU time: 0.49u 0.27s 00:00:00.76 Elapsed: 00:00:00.40
# Mc/sec: 1128.63
//
Query:       EEA23098.1  [L=113]
Description: calmodulin [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.4e-32  109.4   5.8    1.3e-15   57.0   0.6    3.0  3  EF-hand_8        EF-hand domain pair
    1.5e-31  105.6   8.1    4.8e-10   38.3   0.9    3.2  3  EF-hand_1        EF hand
    4.1e-28   97.6   4.2    1.9e-19   69.9   2.2    2.1  2  EF-hand_7        EF-hand domain pair
    1.2e-20   71.5   3.7    4.9e-09   35.4   0.0    3.5  3  EF-hand_6        EF-hand domain
    2.9e-19   67.6   5.1    6.3e-06   25.4   0.0    3.2  3  EF-hand_5        EF hand
    1.7e-11   44.3   0.8     0.0001   22.6   0.1    2.1  2  EF-hand_9        EF-hand domain
    2.1e-07   30.9   2.1    0.00037   20.4   0.3    2.1  2  EF-hand_4        Cytoskeletal-regulatory complex EF hand
    4.6e-06   26.6   0.6    1.1e-05   25.4   0.2    1.8  2  EFhand_Ca_insen  Ca2+ insensitive EF hand
    1.2e-05   25.5   0.3    0.00073   19.8   0.1    2.1  2  SPARC_Ca_bdg     Secreted protein acidic and rich in cysteine
    1.3e-05   25.1   0.1       0.19   11.8   0.0    3.0  3  UPF0154          Uncharacterised protein family (UPF0154)
     0.0001   23.1   0.1      0.001   19.9   0.1    1.9  2  EF-hand_11       EF-hand domain
     0.0054   15.3   0.0     0.0058   15.2   0.0    1.0  1  DUF5580          Family of unknown function (DUF5580)
  ------ inclusion threshold ------
      0.011   15.6   0.8       0.45   10.5   0.1    2.1  2  TerB             Tellurite resistance protein TerB
      0.013   15.4   0.7       0.16   11.9   0.2    2.1  2  SurA_N_2         SurA N-terminal domain
      0.025   15.0   0.1        5.4    7.6   0.0    2.9  3  RuvA_C           RuvA, C-terminal domain
      0.039   14.2   0.0       0.16   12.2   0.0    1.9  2  Poly_export      Polysaccharide biosynthesis/export protein
      0.042   14.2   1.3       0.31   11.4   0.3    2.5  2  RNA_pol_Rpb4     RNA polymerase Rpb4
      0.061   13.5   5.2        0.2   11.9   0.8    2.7  3  Dockerin_1       Dockerin type I domain
      0.069   12.3   0.1       0.51    9.5   0.1    2.0  2  dCache_2         Cache domain
      0.073   12.4   0.1        3.6    6.8   0.0    2.0  2  Herpes_UL36      Herpesvirus UL36 tegument protein
       0.08   13.0   0.5         14    5.9   0.1    2.2  2  DUF5132          Protein of unknown function (DUF5132)


Domain annotation for each model (and alignments):
>> EF-hand_8  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.3   0.0   1.2e-13     1e-10      14      54 ..       1      39 [.       1      40 [. 0.95
   2 !   19.7   0.2   6.4e-07   0.00055      24      46 ..      46      68 ..      37      69 .. 0.84
   3 !   57.0   0.6   1.5e-18   1.3e-15       2      52 ..      62     110 ..      62     112 .. 0.96

  Alignments for each domain:
  == domain 1  score: 41.3 bits;  conditional E-value: 1.2e-13
   EF-hand_8 14 lrilglkkglseeevdilfrefDtdgdGkisfeEFcvller 54
                +r+lg++   se+e++++++e+D d++G+i+f EF+ +++r
  EEA23098.1  1 MRSLGQN--PSESELQDMINEVDADNNGTIDFPEFLTMMAR 39
                5789999..******************************97 PP

  == domain 2  score: 19.7 bits;  conditional E-value: 6.4e-07
   EF-hand_8 24 seeevdilfrefDtdgdGkisfe 46
                seee+++ f+ fD+d++G is  
  EEA23098.1 46 SEEEIREAFKVFDRDNNGFISAA 68
                89****************99965 PP

  == domain 3  score: 57.0 bits;  conditional E-value: 1.5e-18
   EF-hand_8   2 kgkItreelrrilrilglkkglseeevdilfrefDtdgdGkisfeEFcvll 52 
                 +g I+ +elr+ ++++g k  l+++evd+++re+D+dgdG+i+++EF++l+
  EEA23098.1  62 NGFISAAELRHVMTSIGEK--LTDDEVDEMIREADQDGDGRIDYNEFVQLM 110
                 599**********888*99..****************************98 PP

>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.5   0.2   8.8e-12   7.5e-09       1      28 [.      12      39 ..      12      40 .. 0.95
   2 !   36.6   0.0     2e-12   1.7e-09       1      28 [.      49      76 ..      49      77 .. 0.96
   3 !   38.3   0.9   5.6e-13   4.8e-10       1      27 [.      85     111 ..      85     113 .] 0.95

  Alignments for each domain:
  == domain 1  score: 34.5 bits;  conditional E-value: 8.8e-12
                HHHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1  1 elkeiFrefDkDgdGkIdfeEfkellkk 28
                el+++++e+D D++G+Idf Ef++++++
  EEA23098.1 12 ELQDMINEVDADNNGTIDFPEFLTMMAR 39
                799***********************86 PP

  == domain 2  score: 36.6 bits;  conditional E-value: 2e-12
                HHHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1  1 elkeiFrefDkDgdGkIdfeEfkellkk 28
                e++e+F++fD+D++G+I+  E+++++++
  EEA23098.1 49 EIREAFKVFDRDNNGFISAAELRHVMTS 76
                79************************97 PP

  == domain 3  score: 38.3 bits;  conditional E-value: 5.6e-13
                 HHHHHHHHHTTTSSSEEEHHHHHHHHH CS
   EF-hand_1   1 elkeiFrefDkDgdGkIdfeEfkellk 27 
                 e++e++re+D+DgdG+Id++Ef++l++
  EEA23098.1  85 EVDEMIREADQDGDGRIDYNEFVQLMM 111
                 79************************8 PP

>> EF-hand_7  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.1   0.0   2.4e-09     2e-06      36      70 ..       3      37 ..       1      38 [. 0.92
   2 !   69.9   2.2   2.2e-22   1.9e-19       1      70 [.      47     110 ..      47     111 .. 0.98

  Alignments for each domain:
  == domain 1  score: 28.1 bits;  conditional E-value: 2.4e-09
   EF-hand_7 36 gegsklsdeelellfkefDtdkdGvisfdEFlkly 70
                + g ++s+ el+++++e+D d++G+i+f EFl+++
  EEA23098.1  3 SLGQNPSESELQDMINEVDADNNGTIDFPEFLTMM 37
                5678889**************************99 PP

  == domain 2  score: 69.9 bits;  conditional E-value: 2.2e-22
   EF-hand_7   1 eeklkeaFkelDtdgdgyldkeellrllrkifqgagegsklsdeelellfkefDtdkdGvisfdEFlkly 70 
                 ee+++eaFk +D+d++g+++ +el+++++      + g+kl+d+e++++++e D+d+dG+i+++EF++l+
  EEA23098.1  47 EEEIREAFKVFDRDNNGFISAAELRHVMT------SIGEKLTDDEVDEMIREADQDGDGRIDYNEFVQLM 110
                 689**************************......9********************************99 PP

>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.1     1e-05    0.0086       2      27 ..      13      38 ..      12      45 .. 0.86
   2 !   35.4   0.0   5.8e-12   4.9e-09       1      31 []      49      78 ..      49      78 .. 0.94
   3 !   19.9   0.2   5.6e-07   0.00048       7      27 ..      91     111 ..      85     113 .] 0.84

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 1e-05
   EF-hand_6  2 lreaFklfDkdgdGkidaeElrkalr 27
                l++  ++ D d++G+id+ E+  ++ 
  EEA23098.1 13 LQDMINEVDADNNGTIDFPEFLTMMA 38
                67777889**************9986 PP

  == domain 2  score: 35.4 bits;  conditional E-value: 5.8e-12
   EF-hand_6  1 elreaFklfDkdgdGkidaeElrkalrkalg 31
                e+reaFk fD+d++G+i+a+Elr++++ + g
  EEA23098.1 49 EIREAFKVFDRDNNGFISAAELRHVMT-SIG 78
                79************************9.765 PP

  == domain 3  score: 19.9 bits;  conditional E-value: 5.6e-07
   EF-hand_6   7 klfDkdgdGkidaeElrkalr 27 
                 ++ D+dgdG id++E+++++ 
  EEA23098.1  91 READQDGDGRIDYNEFVQLMM 111
                 678**************9886 PP

>> EF-hand_5  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.1   2.1e-07   0.00018       1      25 []      13      37 ..      13      37 .. 0.94
   2 !   25.4   0.0   7.4e-09   6.3e-06       1      25 []      50      74 ..      50      74 .. 0.91
   3 !   22.5   0.4   6.1e-08   5.2e-05       3      25 .]      88     110 ..      86     111 .. 0.87

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 2.1e-07
                HHHHHHHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5  1 lkdtFqaiDlNgDGkIskeELktlv 25
                l+d+ +++D+++ G+I++ E+ t++
  EEA23098.1 13 LQDMINEVDADNNGTIDFPEFLTMM 37
                7899*****************9987 PP

  == domain 2  score: 25.4 bits;  conditional E-value: 7.4e-09
                HHHHHHHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5  1 lkdtFqaiDlNgDGkIskeELktlv 25
                ++++F+ +D ++ G+Is+ EL+ ++
  EEA23098.1 50 IREAFKVFDRDNNGFISAAELRHVM 74
                5778*****************9876 PP

  == domain 3  score: 22.5 bits;  conditional E-value: 6.1e-08
                 HHHHHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5   3 dtFqaiDlNgDGkIskeELktlv 25 
                 ++ +++D +gDG+I+  E+ +l+
  EEA23098.1  88 EMIREADQDGDGRIDYNEFVQLM 110
                 57899**************9875 PP

>> EF-hand_9  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8   0.1   4.2e-07   0.00036      28      64 ..       5      39 ..       1      41 [. 0.90
   2 !   22.6   0.1   1.2e-07    0.0001       3      64 ..      53     112 ..      51     113 .] 0.95

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 4.2e-07
   EF-hand_9 28 taqdpeeseLeelakelDPdgedasvdldtflrvmre 64
                ++ +p+eseL++  +e+D d++ +++d+  fl++m +
  EEA23098.1  5 GQ-NPSESELQDMINEVDADNN-GTIDFPEFLTMMAR 39
                55.9******************.************86 PP

  == domain 2  score: 22.6 bits;  conditional E-value: 1.2e-07
   EF-hand_9   3 vFevcDtqktGrVpvsrlidyLravtaqdpeeseLeelakelDPdgedasvdldtflrvmre 64 
                  F+v+D++  G +  ++l  ++   ++ + ++ e++e  +e+D dg  + +d + f + m++
  EEA23098.1  53 AFKVFDRDNNGFISAAELRHVMTSIGE-KLTDDEVDEMIREADQDGD-GRIDYNEFVQLMMQ 112
                 5*************************9.88999************99.************97 PP

>> EF-hand_4  Cytoskeletal-regulatory complex EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.6   0.1   0.00049      0.42      42      69 ..      10      37 ..       5      45 .. 0.86
   2 !   20.4   0.3   4.4e-07   0.00037       7      69 ..      48     110 ..      40     112 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00049
   EF-hand_4 42 edklekiwdladidedgkldfeefciam 69
                e++l+ + +  d d++g++df ef  +m
  EEA23098.1 10 ESELQDMINEVDADNNGTIDFPEFLTMM 37
                66788888899*************9888 PP

  == domain 2  score: 20.4 bits;  conditional E-value: 4.4e-07
   EF-hand_4   7 leikkyweifsglkpednkltgdkvapvlkn..skleedklekiwdladidedgkldfeefciam 69 
                  ei++ +++f   ++++  ++  ++  v+ +   kl++d+++++   ad d dg++d++ef+  m
  EEA23098.1  48 EEIREAFKVFD--RDNNGFISAAELRHVMTSigEKLTDDEVDEMIREADQDGDGRIDYNEFVQLM 110
                 56666667775..3567789999999999864379**************************9776 PP

>> EFhand_Ca_insen  Ca2+ insensitive EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       3.4   2.9e+03      53      66 ..      23      36 ..      11      38 .. 0.63
   2 !   25.4   0.2   1.3e-08   1.1e-05       1      69 []      43     112 ..      43     112 .. 0.83

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 3.4
                     S-TTEEECCCHTTT CS
  EFhand_Ca_insen 53 avekayDYvsFlea 66
                      +++  D+ +Fl+ 
       EEA23098.1 23 DNNGTIDFPEFLTM 36
                     35667888888875 PP

  == domain 2  score: 25.4 bits;  conditional E-value: 1.3e-08
                      G-STHHHHHCHHHHH.CTTSSSEEHHHHHHH-TT..CHH.HHHHCCSEEE-STT..S-TTEEECCCHTTTTTT CS
  EFhand_Ca_insen   1 dvdsaeqveeaFral.aggKpYvTeedLrrellp..eqa.eylierMpeysgpegdavekayDYvsFlealfa 69 
                      d+ds e+++eaF+    ++  ++ + +Lr+ ++   e+  +  +++M +  +++     +  DY++F++ +++
       EEA23098.1  43 DTDSEEEIREAFKVFdRDNNGFISAAELRHVMTSigEKLtDDEVDEMIREADQD---GDGRIDYNEFVQLMMQ 112
                      89*************888889********9887533555588888888888766...56789*******9986 PP

>> SPARC_Ca_bdg  Secreted protein acidic and rich in cysteine Ca binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0     0.055        47      86     111 ..       9      34 ..       2      36 .. 0.84
   2 !   19.8   0.1   8.6e-07   0.00073      51     111 ..      45     107 ..      34     109 .. 0.85

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.055
  SPARC_Ca_bdg  86 lehCikpflescDadkdkkislkEwc 111
                    e+  + ++++ Dad++++i+  E+ 
    EEA23098.1   9 SESELQDMINEVDADNNGTIDFPEFL 34 
                   5666788999***********99996 PP

  == domain 2  score: 19.8 bits;  conditional E-value: 8.6e-07
  SPARC_Ca_bdg  51 eckepvawkFsklDtnsdkvlsksELaplrapl..vklehCikpflescDadkdkkislkEwc 111
                     +e+++  F+ +D ++++++s +EL+++ +++    ++  ++++++++D+d d++i+ +E++
    EEA23098.1  45 DSEEEIREAFKVFDRDNNGFISAAELRHVMTSIgeKLTDDEVDEMIREADQDGDGRIDYNEFV 107
                   566788889********************9998333468899*******************97 PP

>> UPF0154  Uncharacterised protein family (UPF0154)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   0.0   0.00023      0.19      39      58 ..       1      20 [.       1      22 [. 0.92
   2 ?    0.4   0.1      0.82     7e+02      36      54 ..      35      53 ..      31      59 .. 0.72
   3 !    9.4   0.0    0.0012         1      26      57 ..      61      92 ..      53      95 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00023
     UPF0154 39 mkqmGrkPSekqikqvmrsm 58
                m++ G++PSe+ ++ +++++
  EEA23098.1  1 MRSLGQNPSESELQDMINEV 20
                899*************9987 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.82
     UPF0154 36 rammkqmGrkPSekqikqv 54
                 +m+++m  + Se  i++ 
  EEA23098.1 35 TMMARKMKDTDSEEEIREA 53
                5677888778888877765 PP

  == domain 3  score: 9.4 bits;  conditional E-value: 0.0012
     UPF0154 26 enPpinekmirammkqmGrkPSekqikqvmrs 57
                +n  i++  +r  m + G k++   + +++r+
  EEA23098.1 61 NNGFISAAELRHVMTSIGEKLTDDEVDEMIRE 92
                577899***********************986 PP

>> EF-hand_11  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0      0.28   2.4e+02      58      84 ..      13      39 ..       6      48 .. 0.78
   2 !   19.9   0.1   1.2e-06     0.001      10      80 ..      39     108 ..      35     113 .] 0.86

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.28
                HHHHHHTS-B-TTS-EEHHHHHHHHCS CS
  EF-hand_11 58 fdrlwselpvnakgrlkyqdflsklsi 84
                ++ + +e+  + +g + +++fl+ ++ 
  EEA23098.1 13 LQDMINEVDADNNGTIDFPEFLTMMAR 39
                556778999999999999999988765 PP

  == domain 2  score: 19.9 bits;  conditional E-value: 1.2e-06
                 HHHHHHHHSHHHHHHHHHHH-TT-SSEE-HHHHHHHHHHHT----HHHHHHHHHTS-B-TTS-EEHHHHHH CS
  EF-hand_11  10 rlqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdfls 80 
                 r  k   s    i + f+ fd  +   +s  e+r + t   + ltd++ d +  e   +  gr+ y++f+ 
  EEA23098.1  39 RKMKDTDSE-EEIREAFKVFDRDNNGFISAAELRHVMTSIGEKLTDDEVDEMIREADQDGDGRIDYNEFVQ 108
                 555554443.568899*****************************************************86 PP

>> DUF5580  Family of unknown function (DUF5580)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   6.8e-06    0.0058     293     386 ..      18     111 ..       2     113 .] 0.85

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 6.8e-06
     DUF5580 293 qdsssesevnkslleiLkmalktakgklnlenLnlsFrkeDrsfsGlLpppkvraiCgkhglyltlslletllnhqdlgyqdeikWqnfvelLs 386
                 ++ + +++ + ++ e L m  +++k+  + e+++ +F+  Dr   G+++ +++r +    g  lt   ++ ++   d    + i +++fv+l+ 
  EEA23098.1  18 NEVDADNNGTIDFPEFLTMMARKMKDTDSEEEIREAFKVFDRDNNGFISAAELRHVMTSIGEKLTDDEVDEMIREADQDGDGRIDYNEFVQLMM 111
                 334444555567889999999999999999*************************************************************985 PP

>> TerB  Tellurite resistance protein TerB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.1     0.045        39      64     108 ..      10      54 ..       4      62 .. 0.79
   2 ?   10.5   0.1   0.00053      0.45      44      93 ..      65     112 ..      55     113 .] 0.89

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.045
        TerB  64 peeakallelfeeaeeeavdleqftralkrklspeqrraliealw 108
                 + e+++ + + ++  + ++d+ +f   ++rk+++ + ++ i+  +
  EEA23098.1  10 ESELQDMINEVDADNNGTIDFPEFLTMMARKMKDTDSEEEIREAF 54 
                 66788888888888888***********99999776666555555 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00053
        TerB  44 vsesErqafrellksrfglspeeakallelfeeaeeeavdleqftralkr 93 
                 +s++E +++++ +    +l+++e+++ ++++++  +  +d+ +f++ + +
  EEA23098.1  65 ISAAELRHVMTSI--GEKLTDDEVDEMIREADQDGDGRIDYNEFVQLMMQ 112
                 7889999999999..78889************************998876 PP

>> SurA_N_2  SurA N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0      0.11        90     104     138 ..       2      30 ..       1      37 [. 0.75
   2 ?   11.9   0.2   0.00018      0.16      84     144 ..      55     109 ..      24     110 .. 0.77

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.11
    SurA_N_2 104 eklGltvsdeelqdaiqgnpaikqsFqpetGkFdk 138
                 ++lG + s++elqd+i++  a      +++G +d 
  EEA23098.1   2 RSLGQNPSESELQDMINEVDA------DNNGTIDF 30 
                 6789999*********99776......46666665 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 0.00018
    SurA_N_2  84 qlreqvldqlvseklleqeaeklGltvsdeelqdaiqgnpaikqsFqpetGkFdkeklkqf 144
                 ++ ++  + ++s + l++ + ++G + +d+e++++i++  +      + +G++d +++ q+
  EEA23098.1  55 KVFDRDNNGFISAAELRHVMTSIGEKLTDDEVDEMIREADQ------DGDGRIDYNEFVQL 109
                 44455567889999999*********************999......79999999999886 PP

>> RuvA_C  RuvA, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.0      0.48   4.1e+02      16      31 ..       9      25 ..       9      29 .. 0.77
   2 ?    2.3   0.0      0.27   2.3e+02      31      44 ..      42      55 ..      33      57 .. 0.85
   3 ?    7.6   0.0    0.0063       5.4      17      42 ..      67      93 ..      66      93 .. 0.81

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.48
                -HHHHHHHHHHHHC.-T CS
      RuvA_C 16 kekeaekAvakvla.np 31
                +e e + ++++v+a n 
  EEA23098.1  9 SESELQDMINEVDAdNN 25
                68999*******97433 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.27
                TTS-HHHHHHHHHC CS
      RuvA_C 31 pgasveelIraALk 44
                +++++ee Ir+A k
  EEA23098.1 42 KDTDSEEEIREAFK 55
                6889999****987 PP

  == domain 3  score: 7.6 bits;  conditional E-value: 0.0063
                HHHHHHHHHHHHC.-TTS-HHHHHHHH CS
      RuvA_C 17 ekeaekAvakvla.npgasveelIraA 42
                ++e +++ +++ +  +++ v+e+Ir+A
  EEA23098.1 67 AAELRHVMTSIGEkLTDDEVDEMIREA 93
                6889999999976666666*******9 PP

>> Poly_export  Polysaccharide biosynthesis/export protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00019      0.16      30      70 ..      16      56 ..       6      68 .. 0.84
   2 ?   -0.7   0.0         2   1.7e+03      55      67 ..      81      93 ..      77     105 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00019
  Poly_export 30 alqgylVdpdGtIslPllGkikvaGltveelreeieeklsk 70
                  ++++  d++GtI++P   ++ +  +  ++ +eei+e+++ 
   EEA23098.1 16 MINEVDADNNGTIDFPEFLTMMARKMKDTDSEEEIREAFKV 56
                 4566777999***************************9954 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 2
  Poly_export 55 ltveelreeieek 67
                 lt +e+ e+i+e+
   EEA23098.1 81 LTDDEVDEMIREA 93
                 6778888888775 PP

>> RNA_pol_Rpb4  RNA polymerase Rpb4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0      0.58   4.9e+02     102     120 ..       3      21 ..       1      24 [. 0.84
   2 ?   11.4   0.3   0.00037      0.31      91     118 ..      65      92 ..      21      95 .. 0.94

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.58
                   TGTTTSTSHHHHHHHHHHH CS
  RNA_pol_Rpb4 102 eleerfedeqleeiLdelk 120
                   +l +  ++++l+++++e+ 
    EEA23098.1   3 SLGQNPSESELQDMINEVD 21 
                   6777889*********985 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00037
                   SSHHHHHHHSTTGTTTSTSHHHHHHHHH CS
  RNA_pol_Rpb4  91 esavelktlieeleerfedeqleeiLde 118
                   +sa+el+ ++ ++ e+++d++++e++ e
    EEA23098.1  65 ISAAELRHVMTSIGEKLTDDEVDEMIRE 92 
                   689**********************986 PP

>> Dockerin_1  Dockerin type I domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.2      0.23   1.9e+02      31      50 ..      14      33 ..       4      39 .. 0.73
   2 ?    4.0   0.5     0.069        59      17      52 ..      36      72 ..      16      78 .. 0.65
   3 ?   11.9   0.8   0.00023       0.2       3      53 ..      58     109 ..      56     112 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.23
                CCCHGGGSTT-SSCESHHHH CS
  Dockerin_1 31 ssngkaaDvNgDGrvnalDa 50
                + + +  D +++G+++   +
  EEA23098.1 14 QDMINEVDADNNGTIDFPEF 33
                56778899999999986555 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.069
                HHHHHCT.SSEBTTSCCCHGGGSTT-SSCESHHHHHH CS
  Dockerin_1 17 liinyln.qregqssssngkaaDvNgDGrvnalDall 52
                ++ + +  ++++++  +  k +D +++G ++a  +  
  EEA23098.1 36 MMARKMKdTDSEEEIREAFKVFDRDNNGFISAAELRH 72
                4555555555555566666778888888888877655 PP

  == domain 3  score: 11.9 bits;  conditional E-value: 0.00023
                 ETTSSSC-SHHHHHHHHHHCT.SSEBTTSCCCHGGGSTT-SSCESHHHHHHH CS
  Dockerin_1   3 DVNgDgkVnalDalliinyln.qregqssssngkaaDvNgDGrvnalDallv 53 
                 D +++g ++a  +  +   +  + ++++ +++ + aD +gDGr++   + ++
  EEA23098.1  58 DRDNNGFISAAELRHVMTSIGeKLTDDEVDEMIREADQDGDGRIDYNEFVQL 109
                 778888888888888888888877899999***************9888887 PP

>> dCache_2  Cache domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.31   2.7e+02     238     259 ..       9      30 ..       3      34 .. 0.70
   2 ?    9.5   0.1    0.0006      0.51     188     260 ..      45     104 ..      32     106 .. 0.70

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.31
    dCache_2 238 kgkllqelleaakkkgegfveY 259
                 ++++lq++++  +++++g++++
  EEA23098.1   9 SESELQDMINEVDADNNGTIDF 30 
                 4445778888888877777765 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.0006
    dCache_2 188 elkqellktlksirygnngyifiydtdgniilhplkkelngknllevkdkkgkl.lqelleaakkkgegfveYk 260
                 + ++e+++ +k +  +nng+i +     +++                 +k  ++ + e+++ a+++g+g+++Y+
  EEA23098.1  45 DSEEEIREAFKVFDRDNNGFISAAELRHVMTSIG--------------EKLTDDeVDEMIREADQDGDGRIDYN 104
                 4447777777777777777777777777666666..............33333369*****************7 PP

>> Herpes_UL36  Herpesvirus UL36 tegument protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.0    0.0043       3.6     123     171 ..      16      67 ..      12      84 .. 0.78
   2 ?    3.9   0.0     0.032        28     122     144 ..      88     110 ..      84     113 .] 0.86

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0043
  Herpes_UL36 123 ileaadasndgnidyhelvlelsgdLlqv...paLaeyvdFyrrsYekfldi 171
                  +++++da n+g id+ e++  ++ ++++     +++e ++ + r  + f++ 
   EEA23098.1  16 MINEVDADNNGTIDFPEFLTMMARKMKDTdseEEIREAFKVFDRDNNGFISA 67 
                  68899***********999999988886522257888888888888888875 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.032
  Herpes_UL36 122 eileaadasndgnidyhelvlel 144
                  e++++ad   dg idy e+v+ +
   EEA23098.1  88 EMIREADQDGDGRIDYNEFVQLM 110
                  678999999***********965 PP

>> DUF5132  Protein of unknown function (DUF5132)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.1     0.017        14      30      40 ..      12      22 ..      10      25 .. 0.91
   2 ?    5.5   0.0     0.021        18      13      33 ..      63      83 ..      61      93 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.017
     DUF5132 30 eLeDlvAEvkA 40
                eL+D++ Ev A
  EEA23098.1 12 ELQDMINEVDA 22
                8********99 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.021
     DUF5132 13 giglyeearkaaaevGEeLeD 33
                g + ++e+r  ++ +GE+L D
  EEA23098.1 63 GFISAAELRHVMTSIGEKLTD 83
                5666899************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (113 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       886  (0.0494171); expected 358.6 (0.02)
Passed bias filter:                      572  (0.0319036); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                        21  (0.00117129); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              21  [number of targets reported over threshold]
# CPU time: 0.48u 0.28s 00:00:00.76 Elapsed: 00:00:00.42
# Mc/sec: 814.78
//
Query:       EEA23099.1  [L=113]
Description: calmodulin [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    5.4e-32  109.4   5.8    1.3e-15   57.0   0.6    3.0  3  EF-hand_8        EF-hand domain pair
    1.5e-31  105.6   8.1    4.8e-10   38.3   0.9    3.2  3  EF-hand_1        EF hand
    4.1e-28   97.6   4.2    1.9e-19   69.9   2.2    2.1  2  EF-hand_7        EF-hand domain pair
    1.2e-20   71.5   3.7    4.9e-09   35.4   0.0    3.5  3  EF-hand_6        EF-hand domain
    2.9e-19   67.6   5.1    6.3e-06   25.4   0.0    3.2  3  EF-hand_5        EF hand
    1.7e-11   44.3   0.8     0.0001   22.6   0.1    2.1  2  EF-hand_9        EF-hand domain
    2.1e-07   30.9   2.1    0.00037   20.4   0.3    2.1  2  EF-hand_4        Cytoskeletal-regulatory complex EF hand
    4.6e-06   26.6   0.6    1.1e-05   25.4   0.2    1.8  2  EFhand_Ca_insen  Ca2+ insensitive EF hand
    1.2e-05   25.5   0.3    0.00073   19.8   0.1    2.1  2  SPARC_Ca_bdg     Secreted protein acidic and rich in cysteine
    1.3e-05   25.1   0.1       0.19   11.8   0.0    3.0  3  UPF0154          Uncharacterised protein family (UPF0154)
     0.0001   23.1   0.1      0.001   19.9   0.1    1.9  2  EF-hand_11       EF-hand domain
     0.0054   15.3   0.0     0.0058   15.2   0.0    1.0  1  DUF5580          Family of unknown function (DUF5580)
  ------ inclusion threshold ------
      0.011   15.6   0.8       0.45   10.5   0.1    2.1  2  TerB             Tellurite resistance protein TerB
      0.013   15.4   0.7       0.16   11.9   0.2    2.1  2  SurA_N_2         SurA N-terminal domain
      0.025   15.0   0.1        5.4    7.6   0.0    2.9  3  RuvA_C           RuvA, C-terminal domain
      0.039   14.2   0.0       0.16   12.2   0.0    1.9  2  Poly_export      Polysaccharide biosynthesis/export protein
      0.042   14.2   1.3       0.31   11.4   0.3    2.5  2  RNA_pol_Rpb4     RNA polymerase Rpb4
      0.061   13.5   5.2        0.2   11.9   0.8    2.7  3  Dockerin_1       Dockerin type I domain
      0.069   12.3   0.1       0.51    9.5   0.1    2.0  2  dCache_2         Cache domain
      0.073   12.4   0.1        3.6    6.8   0.0    2.0  2  Herpes_UL36      Herpesvirus UL36 tegument protein
       0.08   13.0   0.5         14    5.9   0.1    2.2  2  DUF5132          Protein of unknown function (DUF5132)


Domain annotation for each model (and alignments):
>> EF-hand_8  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   41.3   0.0   1.2e-13     1e-10      14      54 ..       1      39 [.       1      40 [. 0.95
   2 !   19.7   0.2   6.4e-07   0.00055      24      46 ..      46      68 ..      37      69 .. 0.84
   3 !   57.0   0.6   1.5e-18   1.3e-15       2      52 ..      62     110 ..      62     112 .. 0.96

  Alignments for each domain:
  == domain 1  score: 41.3 bits;  conditional E-value: 1.2e-13
   EF-hand_8 14 lrilglkkglseeevdilfrefDtdgdGkisfeEFcvller 54
                +r+lg++   se+e++++++e+D d++G+i+f EF+ +++r
  EEA23099.1  1 MRSLGQN--PSESELQDMINEVDADNNGTIDFPEFLTMMAR 39
                5789999..******************************97 PP

  == domain 2  score: 19.7 bits;  conditional E-value: 6.4e-07
   EF-hand_8 24 seeevdilfrefDtdgdGkisfe 46
                seee+++ f+ fD+d++G is  
  EEA23099.1 46 SEEEIREAFKVFDRDNNGFISAA 68
                89****************99965 PP

  == domain 3  score: 57.0 bits;  conditional E-value: 1.5e-18
   EF-hand_8   2 kgkItreelrrilrilglkkglseeevdilfrefDtdgdGkisfeEFcvll 52 
                 +g I+ +elr+ ++++g k  l+++evd+++re+D+dgdG+i+++EF++l+
  EEA23099.1  62 NGFISAAELRHVMTSIGEK--LTDDEVDEMIREADQDGDGRIDYNEFVQLM 110
                 599**********888*99..****************************98 PP

>> EF-hand_1  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   34.5   0.2   8.8e-12   7.5e-09       1      28 [.      12      39 ..      12      40 .. 0.95
   2 !   36.6   0.0     2e-12   1.7e-09       1      28 [.      49      76 ..      49      77 .. 0.96
   3 !   38.3   0.9   5.6e-13   4.8e-10       1      27 [.      85     111 ..      85     113 .] 0.95

  Alignments for each domain:
  == domain 1  score: 34.5 bits;  conditional E-value: 8.8e-12
                HHHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1  1 elkeiFrefDkDgdGkIdfeEfkellkk 28
                el+++++e+D D++G+Idf Ef++++++
  EEA23099.1 12 ELQDMINEVDADNNGTIDFPEFLTMMAR 39
                799***********************86 PP

  == domain 2  score: 36.6 bits;  conditional E-value: 2e-12
                HHHHHHHHHTTTSSSEEEHHHHHHHHHH CS
   EF-hand_1  1 elkeiFrefDkDgdGkIdfeEfkellkk 28
                e++e+F++fD+D++G+I+  E+++++++
  EEA23099.1 49 EIREAFKVFDRDNNGFISAAELRHVMTS 76
                79************************97 PP

  == domain 3  score: 38.3 bits;  conditional E-value: 5.6e-13
                 HHHHHHHHHTTTSSSEEEHHHHHHHHH CS
   EF-hand_1   1 elkeiFrefDkDgdGkIdfeEfkellk 27 
                 e++e++re+D+DgdG+Id++Ef++l++
  EEA23099.1  85 EVDEMIREADQDGDGRIDYNEFVQLMM 111
                 79************************8 PP

>> EF-hand_7  EF-hand domain pair
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   28.1   0.0   2.4e-09     2e-06      36      70 ..       3      37 ..       1      38 [. 0.92
   2 !   69.9   2.2   2.2e-22   1.9e-19       1      70 [.      47     110 ..      47     111 .. 0.98

  Alignments for each domain:
  == domain 1  score: 28.1 bits;  conditional E-value: 2.4e-09
   EF-hand_7 36 gegsklsdeelellfkefDtdkdGvisfdEFlkly 70
                + g ++s+ el+++++e+D d++G+i+f EFl+++
  EEA23099.1  3 SLGQNPSESELQDMINEVDADNNGTIDFPEFLTMM 37
                5678889**************************99 PP

  == domain 2  score: 69.9 bits;  conditional E-value: 2.2e-22
   EF-hand_7   1 eeklkeaFkelDtdgdgyldkeellrllrkifqgagegsklsdeelellfkefDtdkdGvisfdEFlkly 70 
                 ee+++eaFk +D+d++g+++ +el+++++      + g+kl+d+e++++++e D+d+dG+i+++EF++l+
  EEA23099.1  47 EEEIREAFKVFDRDNNGFISAAELRHVMT------SIGEKLTDDEVDEMIREADQDGDGRIDYNEFVQLM 110
                 689**************************......9********************************99 PP

>> EF-hand_6  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.9   0.1     1e-05    0.0086       2      27 ..      13      38 ..      12      45 .. 0.86
   2 !   35.4   0.0   5.8e-12   4.9e-09       1      31 []      49      78 ..      49      78 .. 0.94
   3 !   19.9   0.2   5.6e-07   0.00048       7      27 ..      91     111 ..      85     113 .] 0.84

  Alignments for each domain:
  == domain 1  score: 15.9 bits;  conditional E-value: 1e-05
   EF-hand_6  2 lreaFklfDkdgdGkidaeElrkalr 27
                l++  ++ D d++G+id+ E+  ++ 
  EEA23099.1 13 LQDMINEVDADNNGTIDFPEFLTMMA 38
                67777889**************9986 PP

  == domain 2  score: 35.4 bits;  conditional E-value: 5.8e-12
   EF-hand_6  1 elreaFklfDkdgdGkidaeElrkalrkalg 31
                e+reaFk fD+d++G+i+a+Elr++++ + g
  EEA23099.1 49 EIREAFKVFDRDNNGFISAAELRHVMT-SIG 78
                79************************9.765 PP

  == domain 3  score: 19.9 bits;  conditional E-value: 5.6e-07
   EF-hand_6   7 klfDkdgdGkidaeElrkalr 27 
                 ++ D+dgdG id++E+++++ 
  EEA23099.1  91 READQDGDGRIDYNEFVQLMM 111
                 678**************9886 PP

>> EF-hand_5  EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.9   0.1   2.1e-07   0.00018       1      25 []      13      37 ..      13      37 .. 0.94
   2 !   25.4   0.0   7.4e-09   6.3e-06       1      25 []      50      74 ..      50      74 .. 0.91
   3 !   22.5   0.4   6.1e-08   5.2e-05       3      25 .]      88     110 ..      86     111 .. 0.87

  Alignments for each domain:
  == domain 1  score: 20.9 bits;  conditional E-value: 2.1e-07
                HHHHHHHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5  1 lkdtFqaiDlNgDGkIskeELktlv 25
                l+d+ +++D+++ G+I++ E+ t++
  EEA23099.1 13 LQDMINEVDADNNGTIDFPEFLTMM 37
                7899*****************9987 PP

  == domain 2  score: 25.4 bits;  conditional E-value: 7.4e-09
                HHHHHHHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5  1 lkdtFqaiDlNgDGkIskeELktlv 25
                ++++F+ +D ++ G+Is+ EL+ ++
  EEA23099.1 50 IREAFKVFDRDNNGFISAAELRHVM 74
                5778*****************9876 PP

  == domain 3  score: 22.5 bits;  conditional E-value: 6.1e-08
                 HHHHHH-SS-SSCE-HHHHHHHH CS
   EF-hand_5   3 dtFqaiDlNgDGkIskeELktlv 25 
                 ++ +++D +gDG+I+  E+ +l+
  EEA23099.1  88 EMIREADQDGDGRIDYNEFVQLM 110
                 57899**************9875 PP

>> EF-hand_9  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.8   0.1   4.2e-07   0.00036      28      64 ..       5      39 ..       1      41 [. 0.90
   2 !   22.6   0.1   1.2e-07    0.0001       3      64 ..      53     112 ..      51     113 .] 0.95

  Alignments for each domain:
  == domain 1  score: 20.8 bits;  conditional E-value: 4.2e-07
   EF-hand_9 28 taqdpeeseLeelakelDPdgedasvdldtflrvmre 64
                ++ +p+eseL++  +e+D d++ +++d+  fl++m +
  EEA23099.1  5 GQ-NPSESELQDMINEVDADNN-GTIDFPEFLTMMAR 39
                55.9******************.************86 PP

  == domain 2  score: 22.6 bits;  conditional E-value: 1.2e-07
   EF-hand_9   3 vFevcDtqktGrVpvsrlidyLravtaqdpeeseLeelakelDPdgedasvdldtflrvmre 64 
                  F+v+D++  G +  ++l  ++   ++ + ++ e++e  +e+D dg  + +d + f + m++
  EEA23099.1  53 AFKVFDRDNNGFISAAELRHVMTSIGE-KLTDDEVDEMIREADQDGD-GRIDYNEFVQLMMQ 112
                 5*************************9.88999************99.************97 PP

>> EF-hand_4  Cytoskeletal-regulatory complex EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   10.6   0.1   0.00049      0.42      42      69 ..      10      37 ..       5      45 .. 0.86
   2 !   20.4   0.3   4.4e-07   0.00037       7      69 ..      48     110 ..      40     112 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00049
   EF-hand_4 42 edklekiwdladidedgkldfeefciam 69
                e++l+ + +  d d++g++df ef  +m
  EEA23099.1 10 ESELQDMINEVDADNNGTIDFPEFLTMM 37
                66788888899*************9888 PP

  == domain 2  score: 20.4 bits;  conditional E-value: 4.4e-07
   EF-hand_4   7 leikkyweifsglkpednkltgdkvapvlkn..skleedklekiwdladidedgkldfeefciam 69 
                  ei++ +++f   ++++  ++  ++  v+ +   kl++d+++++   ad d dg++d++ef+  m
  EEA23099.1  48 EEIREAFKVFD--RDNNGFISAAELRHVMTSigEKLTDDEVDEMIREADQDGDGRIDYNEFVQLM 110
                 56666667775..3567789999999999864379**************************9776 PP

>> EFhand_Ca_insen  Ca2+ insensitive EF hand
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.6   0.0       3.4   2.9e+03      53      66 ..      23      36 ..      11      38 .. 0.63
   2 !   25.4   0.2   1.3e-08   1.1e-05       1      69 []      43     112 ..      43     112 .. 0.83

  Alignments for each domain:
  == domain 1  score: -1.6 bits;  conditional E-value: 3.4
                     S-TTEEECCCHTTT CS
  EFhand_Ca_insen 53 avekayDYvsFlea 66
                      +++  D+ +Fl+ 
       EEA23099.1 23 DNNGTIDFPEFLTM 36
                     35667888888875 PP

  == domain 2  score: 25.4 bits;  conditional E-value: 1.3e-08
                      G-STHHHHHCHHHHH.CTTSSSEEHHHHHHH-TT..CHH.HHHHCCSEEE-STT..S-TTEEECCCHTTTTTT CS
  EFhand_Ca_insen   1 dvdsaeqveeaFral.aggKpYvTeedLrrellp..eqa.eylierMpeysgpegdavekayDYvsFlealfa 69 
                      d+ds e+++eaF+    ++  ++ + +Lr+ ++   e+  +  +++M +  +++     +  DY++F++ +++
       EEA23099.1  43 DTDSEEEIREAFKVFdRDNNGFISAAELRHVMTSigEKLtDDEVDEMIREADQD---GDGRIDYNEFVQLMMQ 112
                      89*************888889********9887533555588888888888766...56789*******9986 PP

>> SPARC_Ca_bdg  Secreted protein acidic and rich in cysteine Ca binding region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.4   0.0     0.055        47      86     111 ..       9      34 ..       2      36 .. 0.84
   2 !   19.8   0.1   8.6e-07   0.00073      51     111 ..      45     107 ..      34     109 .. 0.85

  Alignments for each domain:
  == domain 1  score: 4.4 bits;  conditional E-value: 0.055
  SPARC_Ca_bdg  86 lehCikpflescDadkdkkislkEwc 111
                    e+  + ++++ Dad++++i+  E+ 
    EEA23099.1   9 SESELQDMINEVDADNNGTIDFPEFL 34 
                   5666788999***********99996 PP

  == domain 2  score: 19.8 bits;  conditional E-value: 8.6e-07
  SPARC_Ca_bdg  51 eckepvawkFsklDtnsdkvlsksELaplrapl..vklehCikpflescDadkdkkislkEwc 111
                     +e+++  F+ +D ++++++s +EL+++ +++    ++  ++++++++D+d d++i+ +E++
    EEA23099.1  45 DSEEEIREAFKVFDRDNNGFISAAELRHVMTSIgeKLTDDEVDEMIREADQDGDGRIDYNEFV 107
                   566788889********************9998333468899*******************97 PP

>> UPF0154  Uncharacterised protein family (UPF0154)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.8   0.0   0.00023      0.19      39      58 ..       1      20 [.       1      22 [. 0.92
   2 ?    0.4   0.1      0.82     7e+02      36      54 ..      35      53 ..      31      59 .. 0.72
   3 !    9.4   0.0    0.0012         1      26      57 ..      61      92 ..      53      95 .. 0.89

  Alignments for each domain:
  == domain 1  score: 11.8 bits;  conditional E-value: 0.00023
     UPF0154 39 mkqmGrkPSekqikqvmrsm 58
                m++ G++PSe+ ++ +++++
  EEA23099.1  1 MRSLGQNPSESELQDMINEV 20
                899*************9987 PP

  == domain 2  score: 0.4 bits;  conditional E-value: 0.82
     UPF0154 36 rammkqmGrkPSekqikqv 54
                 +m+++m  + Se  i++ 
  EEA23099.1 35 TMMARKMKDTDSEEEIREA 53
                5677888778888877765 PP

  == domain 3  score: 9.4 bits;  conditional E-value: 0.0012
     UPF0154 26 enPpinekmirammkqmGrkPSekqikqvmrs 57
                +n  i++  +r  m + G k++   + +++r+
  EEA23099.1 61 NNGFISAAELRHVMTSIGEKLTDDEVDEMIRE 92
                577899***********************986 PP

>> EF-hand_11  EF-hand domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.6   0.0      0.28   2.4e+02      58      84 ..      13      39 ..       6      48 .. 0.78
   2 !   19.9   0.1   1.2e-06     0.001      10      80 ..      39     108 ..      35     113 .] 0.86

  Alignments for each domain:
  == domain 1  score: 2.6 bits;  conditional E-value: 0.28
                HHHHHHTS-B-TTS-EEHHHHHHHHCS CS
  EF-hand_11 58 fdrlwselpvnakgrlkyqdflsklsi 84
                ++ + +e+  + +g + +++fl+ ++ 
  EEA23099.1 13 LQDMINEVDADNNGTIDFPEFLTMMAR 39
                556778999999999999999988765 PP

  == domain 2  score: 19.9 bits;  conditional E-value: 1.2e-06
                 HHHHHHHHSHHHHHHHHHHH-TT-SSEE-HHHHHHHHHHHT----HHHHHHHHHTS-B-TTS-EEHHHHHH CS
  EF-hand_11  10 rlqkavashyhaivqefenfdtlksntvsreefraictrrvqiltdeqfdrlwselpvnakgrlkyqdfls 80 
                 r  k   s    i + f+ fd  +   +s  e+r + t   + ltd++ d +  e   +  gr+ y++f+ 
  EEA23099.1  39 RKMKDTDSE-EEIREAFKVFDRDNNGFISAAELRHVMTSIGEKLTDDEVDEMIREADQDGDGRIDYNEFVQ 108
                 555554443.568899*****************************************************86 PP

>> DUF5580  Family of unknown function (DUF5580)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.2   0.0   6.8e-06    0.0058     293     386 ..      18     111 ..       2     113 .] 0.85

  Alignments for each domain:
  == domain 1  score: 15.2 bits;  conditional E-value: 6.8e-06
     DUF5580 293 qdsssesevnkslleiLkmalktakgklnlenLnlsFrkeDrsfsGlLpppkvraiCgkhglyltlslletllnhqdlgyqdeikWqnfvelLs 386
                 ++ + +++ + ++ e L m  +++k+  + e+++ +F+  Dr   G+++ +++r +    g  lt   ++ ++   d    + i +++fv+l+ 
  EEA23099.1  18 NEVDADNNGTIDFPEFLTMMARKMKDTDSEEEIREAFKVFDRDNNGFISAAELRHVMTSIGEKLTDDEVDEMIREADQDGDGRIDYNEFVQLMM 111
                 334444555567889999999999999999*************************************************************985 PP

>> TerB  Tellurite resistance protein TerB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.2   0.1     0.045        39      64     108 ..      10      54 ..       4      62 .. 0.79
   2 ?   10.5   0.1   0.00053      0.45      44      93 ..      65     112 ..      55     113 .] 0.89

  Alignments for each domain:
  == domain 1  score: 4.2 bits;  conditional E-value: 0.045
        TerB  64 peeakallelfeeaeeeavdleqftralkrklspeqrraliealw 108
                 + e+++ + + ++  + ++d+ +f   ++rk+++ + ++ i+  +
  EEA23099.1  10 ESELQDMINEVDADNNGTIDFPEFLTMMARKMKDTDSEEEIREAF 54 
                 66788888888888888***********99999776666555555 PP

  == domain 2  score: 10.5 bits;  conditional E-value: 0.00053
        TerB  44 vsesErqafrellksrfglspeeakallelfeeaeeeavdleqftralkr 93 
                 +s++E +++++ +    +l+++e+++ ++++++  +  +d+ +f++ + +
  EEA23099.1  65 ISAAELRHVMTSI--GEKLTDDEVDEMIREADQDGDGRIDYNEFVQLMMQ 112
                 7889999999999..78889************************998876 PP

>> SurA_N_2  SurA N-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.9   0.0      0.11        90     104     138 ..       2      30 ..       1      37 [. 0.75
   2 ?   11.9   0.2   0.00018      0.16      84     144 ..      55     109 ..      24     110 .. 0.77

  Alignments for each domain:
  == domain 1  score: 2.9 bits;  conditional E-value: 0.11
    SurA_N_2 104 eklGltvsdeelqdaiqgnpaikqsFqpetGkFdk 138
                 ++lG + s++elqd+i++  a      +++G +d 
  EEA23099.1   2 RSLGQNPSESELQDMINEVDA------DNNGTIDF 30 
                 6789999*********99776......46666665 PP

  == domain 2  score: 11.9 bits;  conditional E-value: 0.00018
    SurA_N_2  84 qlreqvldqlvseklleqeaeklGltvsdeelqdaiqgnpaikqsFqpetGkFdkeklkqf 144
                 ++ ++  + ++s + l++ + ++G + +d+e++++i++  +      + +G++d +++ q+
  EEA23099.1  55 KVFDRDNNGFISAAELRHVMTSIGEKLTDDEVDEMIREADQ------DGDGRIDYNEFVQL 109
                 44455567889999999*********************999......79999999999886 PP

>> RuvA_C  RuvA, C-terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.5   0.0      0.48   4.1e+02      16      31 ..       9      25 ..       9      29 .. 0.77
   2 ?    2.3   0.0      0.27   2.3e+02      31      44 ..      42      55 ..      33      57 .. 0.85
   3 ?    7.6   0.0    0.0063       5.4      17      42 ..      67      93 ..      66      93 .. 0.81

  Alignments for each domain:
  == domain 1  score: 1.5 bits;  conditional E-value: 0.48
                -HHHHHHHHHHHHC.-T CS
      RuvA_C 16 kekeaekAvakvla.np 31
                +e e + ++++v+a n 
  EEA23099.1  9 SESELQDMINEVDAdNN 25
                68999*******97433 PP

  == domain 2  score: 2.3 bits;  conditional E-value: 0.27
                TTS-HHHHHHHHHC CS
      RuvA_C 31 pgasveelIraALk 44
                +++++ee Ir+A k
  EEA23099.1 42 KDTDSEEEIREAFK 55
                6889999****987 PP

  == domain 3  score: 7.6 bits;  conditional E-value: 0.0063
                HHHHHHHHHHHHC.-TTS-HHHHHHHH CS
      RuvA_C 17 ekeaekAvakvla.npgasveelIraA 42
                ++e +++ +++ +  +++ v+e+Ir+A
  EEA23099.1 67 AAELRHVMTSIGEkLTDDEVDEMIREA 93
                6889999999976666666*******9 PP

>> Poly_export  Polysaccharide biosynthesis/export protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.0   0.00019      0.16      30      70 ..      16      56 ..       6      68 .. 0.84
   2 ?   -0.7   0.0         2   1.7e+03      55      67 ..      81      93 ..      77     105 .. 0.77

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 0.00019
  Poly_export 30 alqgylVdpdGtIslPllGkikvaGltveelreeieeklsk 70
                  ++++  d++GtI++P   ++ +  +  ++ +eei+e+++ 
   EEA23099.1 16 MINEVDADNNGTIDFPEFLTMMARKMKDTDSEEEIREAFKV 56
                 4566777999***************************9954 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 2
  Poly_export 55 ltveelreeieek 67
                 lt +e+ e+i+e+
   EEA23099.1 81 LTDDEVDEMIREA 93
                 6778888888775 PP

>> RNA_pol_Rpb4  RNA polymerase Rpb4
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    1.0   0.0      0.58   4.9e+02     102     120 ..       3      21 ..       1      24 [. 0.84
   2 ?   11.4   0.3   0.00037      0.31      91     118 ..      65      92 ..      21      95 .. 0.94

  Alignments for each domain:
  == domain 1  score: 1.0 bits;  conditional E-value: 0.58
                   TGTTTSTSHHHHHHHHHHH CS
  RNA_pol_Rpb4 102 eleerfedeqleeiLdelk 120
                   +l +  ++++l+++++e+ 
    EEA23099.1   3 SLGQNPSESELQDMINEVD 21 
                   6777889*********985 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00037
                   SSHHHHHHHSTTGTTTSTSHHHHHHHHH CS
  RNA_pol_Rpb4  91 esavelktlieeleerfedeqleeiLde 118
                   +sa+el+ ++ ++ e+++d++++e++ e
    EEA23099.1  65 ISAAELRHVMTSIGEKLTDDEVDEMIRE 92 
                   689**********************986 PP

>> Dockerin_1  Dockerin type I domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    2.3   0.2      0.23   1.9e+02      31      50 ..      14      33 ..       4      39 .. 0.73
   2 ?    4.0   0.5     0.069        59      17      52 ..      36      72 ..      16      78 .. 0.65
   3 ?   11.9   0.8   0.00023       0.2       3      53 ..      58     109 ..      56     112 .. 0.84

  Alignments for each domain:
  == domain 1  score: 2.3 bits;  conditional E-value: 0.23
                CCCHGGGSTT-SSCESHHHH CS
  Dockerin_1 31 ssngkaaDvNgDGrvnalDa 50
                + + +  D +++G+++   +
  EEA23099.1 14 QDMINEVDADNNGTIDFPEF 33
                56778899999999986555 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.069
                HHHHHCT.SSEBTTSCCCHGGGSTT-SSCESHHHHHH CS
  Dockerin_1 17 liinyln.qregqssssngkaaDvNgDGrvnalDall 52
                ++ + +  ++++++  +  k +D +++G ++a  +  
  EEA23099.1 36 MMARKMKdTDSEEEIREAFKVFDRDNNGFISAAELRH 72
                4555555555555566666778888888888877655 PP

  == domain 3  score: 11.9 bits;  conditional E-value: 0.00023
                 ETTSSSC-SHHHHHHHHHHCT.SSEBTTSCCCHGGGSTT-SSCESHHHHHHH CS
  Dockerin_1   3 DVNgDgkVnalDalliinyln.qregqssssngkaaDvNgDGrvnalDallv 53 
                 D +++g ++a  +  +   +  + ++++ +++ + aD +gDGr++   + ++
  EEA23099.1  58 DRDNNGFISAAELRHVMTSIGeKLTDDEVDEMIREADQDGDGRIDYNEFVQL 109
                 778888888888888888888877899999***************9888887 PP

>> dCache_2  Cache domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    0.5   0.0      0.31   2.7e+02     238     259 ..       9      30 ..       3      34 .. 0.70
   2 ?    9.5   0.1    0.0006      0.51     188     260 ..      45     104 ..      32     106 .. 0.70

  Alignments for each domain:
  == domain 1  score: 0.5 bits;  conditional E-value: 0.31
    dCache_2 238 kgkllqelleaakkkgegfveY 259
                 ++++lq++++  +++++g++++
  EEA23099.1   9 SESELQDMINEVDADNNGTIDF 30 
                 4445778888888877777765 PP

  == domain 2  score: 9.5 bits;  conditional E-value: 0.0006
    dCache_2 188 elkqellktlksirygnngyifiydtdgniilhplkkelngknllevkdkkgkl.lqelleaakkkgegfveYk 260
                 + ++e+++ +k +  +nng+i +     +++                 +k  ++ + e+++ a+++g+g+++Y+
  EEA23099.1  45 DSEEEIREAFKVFDRDNNGFISAAELRHVMTSIG--------------EKLTDDeVDEMIREADQDGDGRIDYN 104
                 4447777777777777777777777777666666..............33333369*****************7 PP

>> Herpes_UL36  Herpesvirus UL36 tegument protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    6.8   0.0    0.0043       3.6     123     171 ..      16      67 ..      12      84 .. 0.78
   2 ?    3.9   0.0     0.032        28     122     144 ..      88     110 ..      84     113 .] 0.86

  Alignments for each domain:
  == domain 1  score: 6.8 bits;  conditional E-value: 0.0043
  Herpes_UL36 123 ileaadasndgnidyhelvlelsgdLlqv...paLaeyvdFyrrsYekfldi 171
                  +++++da n+g id+ e++  ++ ++++     +++e ++ + r  + f++ 
   EEA23099.1  16 MINEVDADNNGTIDFPEFLTMMARKMKDTdseEEIREAFKVFDRDNNGFISA 67 
                  68899***********999999988886522257888888888888888875 PP

  == domain 2  score: 3.9 bits;  conditional E-value: 0.032
  Herpes_UL36 122 eileaadasndgnidyhelvlel 144
                  e++++ad   dg idy e+v+ +
   EEA23099.1  88 EMIREADQDGDGRIDYNEFVQLM 110
                  678999999***********965 PP

>> DUF5132  Protein of unknown function (DUF5132)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    5.9   0.1     0.017        14      30      40 ..      12      22 ..      10      25 .. 0.91
   2 ?    5.5   0.0     0.021        18      13      33 ..      63      83 ..      61      93 .. 0.88

  Alignments for each domain:
  == domain 1  score: 5.9 bits;  conditional E-value: 0.017
     DUF5132 30 eLeDlvAEvkA 40
                eL+D++ Ev A
  EEA23099.1 12 ELQDMINEVDA 22
                8********99 PP

  == domain 2  score: 5.5 bits;  conditional E-value: 0.021
     DUF5132 13 giglyeearkaaaevGEeLeD 33
                g + ++e+r  ++ +GE+L D
  EEA23099.1 63 GFISAAELRHVMTSIGEKLTD 83
                5666899************98 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (113 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       886  (0.0494171); expected 358.6 (0.02)
Passed bias filter:                      572  (0.0319036); expected 358.6 (0.02)
Passed Vit filter:                        63  (0.00351386); expected 17.9 (0.001)
Passed Fwd filter:                        21  (0.00117129); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              21  [number of targets reported over threshold]
# CPU time: 0.46u 0.27s 00:00:00.73 Elapsed: 00:00:00.42
# Mc/sec: 816.43
//
Query:       EEA23100.1  [L=413]
Description: SNARE complex subunit (Tlg2), putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.1e-16   59.7   1.7    5.1e-16   58.4   1.7    1.7  1  SNARE         SNARE domain
  ------ inclusion threshold ------
       0.01   15.5  13.8      0.026   14.2  13.8    1.7  1  Syntaxin      Syntaxin
      0.041   14.1   0.1      0.041   14.1   0.1    3.3  4  KxDL          Uncharacterized conserved protein
       0.07   13.3   0.0       0.17   12.1   0.0    1.5  1  DUF2615       Protein of unknown function (DUF2615)
        2.1    8.6   6.9         32    4.9   0.1    3.9  4  DUF948        Bacterial protein of unknown function (DUF948)
        3.4    7.2   8.8        0.2   11.2   1.4    2.1  3  HAUS-augmin3  HAUS augmin-like complex subunit 3
        4.2    7.1  11.1        2.3    8.0   2.3    2.5  2  BBP1_C        Spindle pole body component BBP1, C-terminal
          6    6.1  12.3      0.076   12.3   0.5    2.3  2  DUF4407       Domain of unknown function (DUF4407)


Domain annotation for each model (and alignments):
>> SNARE  SNARE domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   58.4   1.7   2.3e-19   5.1e-16       1      53 []     281     333 ..     281     333 .. 0.98

  Alignments for each domain:
  == domain 1  score: 58.4 bits;  conditional E-value: 2.3e-19
                 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTXXXXXXXXXXXXXXXXXXXX CS
       SNARE   1 emvDrIdtnVenaqsnveraqkeLkkavkyqksnRklkciillilviillvvl 53 
                 +m+DrId+nVe+  ++v++a  eLk a++yq+++ k k+i+llilv i+++vl
  EEA23100.1 281 TMLDRIDYNVERMATDVKQADTELKVASNYQRKTTKRKIILLLILVMIGMIVL 333
                 7**************************************************96 PP

>> Syntaxin  Syntaxin
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.2  13.8   1.2e-05     0.026       9     200 .]      75     280 ..      70     280 .. 0.81

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 1.2e-05
    Syntaxin   9 eeikkeiekleeevkklkkqne.esktstraksvklkkr...mesdikeikkraesvkarLeaLdksnkenekksgegsavdRirksqtaaLrkklkev 103
                 ee+++ +++++++ ++l+k ++ +++ s   + v+ k++   +e+ +++i+++ +++++ ++++d  ++e+++    ++ ++ ++k +  +L  + +e+
  EEA23100.1  75 EEVSEVLADIAQKSARLDKLHQkHILPSFGDEGVR-KEEeaiIEQYTQQITRSFHACQNAIQRIDGLVREQKQLGAVTKGDETMAKNIQISLAARVQEA 172
                 56778888888888888887651567778888883.3332235777889999********************99999999******************* PP

    Syntaxin 104 mteynelrekireeyker..ieRrlevtGkevseeeie.elietgesevflqkllqeq.rgareal.....s..eieeRhkevlelekslkeLhqlFld 191
                    +++ +++   + +e       +e +++ ++ +  +  l+e++  ++f+q+ lq++ + ++++l     +   i +R +e+ ++ k + eL ++F +
  EEA23100.1 173 SARFRKKQSTYLRKLRELegMASPFERVSTPIQSQYSDpSLMESDADKSFSQTTLQQTsQKQQQQLvvsgaNdvAIAQREREINDIAKGIIELSDIFRE 271
                 ***************98622555599999988888877579*************9999766666662333322245*********************** PP

    Syntaxin 192 mavLVEeQG 200
                 + +++  QG
  EEA23100.1 272 LQTMIIDQG 280
                 **9999998 PP

>> KxDL  Uncharacterized conserved protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.7   0.1       1.6   3.6e+03      21      34 ..      80      93 ..      71      98 .. 0.36
   2 ?   14.1   0.1   1.8e-05     0.041       9      83 ..     135     209 ..     126     211 .. 0.90
   3 ?   -1.0   1.2      0.97   2.2e+03       5      21 ..     221     237 ..     219     245 .. 0.75
   4 ?   -0.3   0.1      0.61   1.4e+03      10      46 ..     271     307 ..     263     317 .. 0.67

  Alignments for each domain:
  == domain 1  score: -1.7 bits;  conditional E-value: 1.6
        KxDL 21 tsgrlnkknreLle 34
                +++ + +k+++L +
  EEA23100.1 80 VLADIAQKSARLDK 93
                22222222222222 PP

  == domain 2  score: 14.1 bits;  conditional E-value: 1.8e-05
        KxDL   9 edldeilalQaqtsgrlnkknreLlelnalsqerlaklrarfkqgtkllkevkkdLesifkkirslkaklakkyP 83 
                 +++d  ++ Q+q+ ++ +  + + ++++  + +r+++++arf++++ +  +  ++Le + +  ++  + ++++y 
  EEA23100.1 135 QRIDGLVREQKQLGAVTKGDETMAKNIQISLAARVQEASARFRKKQSTYLRKLRELEGMASPFERVSTPIQSQYS 209
                 678999**************************************************9998888887777777775 PP

  == domain 3  score: -1.0 bits;  conditional E-value: 0.97
        KxDL   5 avdsedldeilalQaqt 21 
                 ++++++l+++ ++Q+q 
  EEA23100.1 221 SFSQTTLQQTSQKQQQQ 237
                 67778888888888774 PP

  == domain 4  score: -0.3 bits;  conditional E-value: 0.61
        KxDL  10 dldeilalQaqtsgrlnkknreLlelnalsqerlakl 46 
                 +l++++  Q  +++r+    +++ +  ++++++l+ +
  EEA23100.1 271 ELQTMIIDQGTMLDRIDYNVERMATDVKQADTELKVA 307
                 4677777777777777766666666666666666554 PP

>> DUF2615  Protein of unknown function (DUF2615)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   7.4e-05      0.17      43     102 ..     306     365 ..     290     367 .. 0.64

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 7.4e-05
     DUF2615  43 lpgpeaskeggsslfliallwlvvaavlfllrPsslrna.saknkpsrkdnnddddsqepp 102
                 ++++ + k ++ +++l+++l+++  +vl +l+P+  +n+ s+++ p  +++  +  +q+pp
  EEA23100.1 306 VASNYQRKTTKRKIILLLILVMIGMIVLLALKPKRHSNTnSDTTTPPPQEDIVN-GQQKPP 365
                 445555667777888888888888999*******99998544445544444444.344443 PP

>> DUF948  Bacterial protein of unknown function (DUF948)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.1   0.1     0.025        56      53      75 ..      74      96 ..      69      98 .. 0.86
   2 ?    0.5   0.0      0.32   7.2e+02      57      82 ..     124     149 ..     108     206 .. 0.70
   3 ?    4.9   0.1     0.014        32      18      68 ..     259     307 ..     257     311 .. 0.88
   4 ?   -1.2   0.1       1.1   2.6e+03      10      25 ..     322     337 ..     320     349 .. 0.78

  Alignments for each domain:
  == domain 1  score: 4.1 bits;  conditional E-value: 0.025
      DUF948 53 lakvnelledvneklekvdplte 75
                 ++v e+l+d+ +k++++d+l +
  EEA23100.1 74 QEEVSEVLADIAQKSARLDKLHQ 96
                578999*************9865 PP

  == domain 2  score: 0.5 bits;  conditional E-value: 0.32
      DUF948  57 nelledvneklekvdplteavadlge 82 
                  +    +++ ++++d l+ + ++lg+
  EEA23100.1 124 TRSFHACQNAIQRIDGLVREQKQLGA 149
                 33333444555555555555555554 PP

  == domain 3  score: 4.9 bits;  conditional E-value: 0.014
      DUF948  18 ivvllklkktldeaaatieelekqvdpilkevedllakvnelledvnekle 68 
                 ++ +++l+++++e++++i + +  +d i  +ve++ + v++  +d + k++
  EEA23100.1 259 AKGIIELSDIFRELQTMIIDQGTMLDRIDYNVERMATDVKQ--ADTELKVA 307
                 5668999******************************9999..77777665 PP

  == domain 4  score: -1.2 bits;  conditional E-value: 1.1
      DUF948  10 FvvLviflivvllklk 25 
                 +++Lv++ ++vll lk
  EEA23100.1 322 LLILVMIGMIVLLALK 337
                 5899999999999995 PP

>> HAUS-augmin3  HAUS augmin-like complex subunit 3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.0   0.9      0.48   1.1e+03      91     151 ..     117     180 ..      74     185 .. 0.61
   2 ?   -0.2   0.3      0.27     6e+02      63     115 ..     146     201 ..     128     223 .. 0.58
   3 ?   11.2   1.4   8.7e-05       0.2      42     141 ..     211     309 ..     206     317 .. 0.84

  Alignments for each domain:
  == domain 1  score: -1.0 bits;  conditional E-value: 0.48
  HAUS-augmin3  91 qkekalklkrlnkLqvqaas...lqqelrkleeeekeakkklkeaqeelraenaetnavLqqlt 151
                   +++ + +++ +   q ++     l +e+++l + +k  +   k++q +l+a+  e++a + + +
    EEA23100.1 117 EQYTQQITRSFHACQNAIQRidgLVREQKQLGAVTKGDETMAKNIQISLAARVQEASARFRKKQ 180
                   3444444455555554444311134566777777777777777777777777777777666655 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.27
  HAUS-augmin3  63 q..edvellevileeeeesleaLeqelqe.LqkekalklkrlnkLqvqaaslqqel 115
                   q    ++  e  +++++ sl a  qe+++  +k +   l++l +L+ +a+  ++++
    EEA23100.1 146 QlgAVTKGDETMAKNIQISLAARVQEASArFRKKQSTYLRKLRELEGMASPFERVS 201
                   23334444455555555555555555443255666667777777777777666655 PP

  == domain 3  score: 11.2 bits;  conditional E-value: 8.7e-05
  HAUS-augmin3  42 piLegeaLeeaLktiepsdlkqedvellevileeeeesleaLeqelqeLqkekalklkrlnkLqvqaaslqqelrkleeeekeakkklkeaqeelra 138
                   p L +++ ++ + +   ++ +q ++++  v   + + ++ + e+e+++  k    +   + +Lq ++ ++   l + + + + ++ ++k+a+ el++
    EEA23100.1 211 PSLMESDADKSFSQTTLQQTSQ-KQQQQLVVSGANDVAIAQREREINDIAKGIIELSDIFRELQTMIIDQGTMLDRIDYNVERMATDVKQADTELKV 306
                   6788888888888887333334.3333346666679************************************************************9 PP

  HAUS-augmin3 139 ena 141
                   +++
    EEA23100.1 307 ASN 309
                   886 PP

>> BBP1_C  Spindle pole body component BBP1, C-terminal
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.0   2.3     0.001       2.3     113     172 ..     160     235 ..     135     251 .. 0.66
   2 ?    4.3   0.8     0.014        32      75     140 ..     254     319 ..     246     353 .. 0.88

  Alignments for each domain:
  == domain 1  score: 8.0 bits;  conditional E-value: 0.001
      BBP1_C 113 eklldlelrnkeleekreidkikYesrikdLe...rqllereneik.............dtssssnafstseyrkk 172
                 +  ++l+ r +e+ +++ + +  Y +++++Le      +  +++i+             d+s+s+ + ++ + +++
  EEA23100.1 160 NIQISLAARVQEASARFRKKQSTYLRKLRELEgmaSPFERVSTPIQsqysdpslmesdaDKSFSQTTLQQTSQKQQ 235
                 33478999************************66433333444444544444444444444444444444443333 PP

  == domain 2  score: 4.3 bits;  conditional E-value: 0.014
      BBP1_C  75 eLkkiskesldlqskianlekqlvdqaiekdreikkleeklldlelrnkeleekreidkikYesri 140
                 e+  i+k  ++l++   +l+  ++dq    dr + ++e+   d++  ++el+ + + ++   +++i
  EEA23100.1 254 EINDIAKGIIELSDIFRELQTMIIDQGTMLDRIDYNVERMATDVKQADTELKVASNYQRKTTKRKI 319
                 566788888899999************************************999999888877777 PP

>> DUF4407  Domain of unknown function (DUF4407)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.5   3.4e-05     0.076     190     260 ..      82     157 ..      73     167 .. 0.91
   2 ?   -2.3   6.0         1   2.3e+03     196     225 ..     224     261 ..     155     319 .. 0.46

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 3.4e-05
     DUF4407 190 aqldaaqaelaelkakld.....atarlaalraelaeleaerakeraasqaaaaaddGllarlealdrltkedata 260
                 a++++++a+l++l++k        +  +++ +a +++ +++++++  a q a++  dGl  + + l+++tk d t+
  EEA23100.1  82 ADIAQKSARLDKLHQKHIlpsfgDEGVRKEEEAIIEQYTQQITRSFHACQNAIQRIDGLVREQKQLGAVTKGDETM 157
                 78999***********88****99999999*****************************************99965 PP

  == domain 2  score: -2.3 bits;  conditional E-value: 1
     DUF4407 196 qaelaelkakld........atarlaalraelaeleae 225
                 q++l++ ++k +        ++ ++a++++e++++++ 
  EEA23100.1 224 QTTLQQTSQKQQqqlvvsgaNDVAIAQREREINDIAKG 261
                 22222222222222223333444444444444444332 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (413 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1702  (0.09493); expected 358.6 (0.02)
Passed bias filter:                      872  (0.0486363); expected 358.6 (0.02)
Passed Vit filter:                        82  (0.0045736); expected 17.9 (0.001)
Passed Fwd filter:                         9  (0.00050198); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               8  [number of targets reported over threshold]
# CPU time: 0.70u 0.32s 00:00:01.02 Elapsed: 00:00:00.50
# Mc/sec: 2509.38
//
Query:       EEA23101.1  [L=366]
Description: DUF618 domain protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    4.4e-19   69.1   0.1    1.2e-18   67.6   0.1    1.8  1  CTD_bind  RNA polymerase II-binding domain.
  ------ inclusion threshold ------
      0.062   13.2   0.0       0.11   12.3   0.0    1.4  1  DUF3277   Protein of unknown function (DUF3277)
      0.062   13.3   0.1       0.14   12.2   0.1    1.5  1  CTK3      CTD kinase subunit gamma CTK3
       0.64   10.2   2.4        1.4    9.0   0.3    2.5  3  TetR_C_4  YsiA-like protein, C-terminal region


Domain annotation for each model (and alignments):
>> CTD_bind  RNA polymerase II-binding domain.
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   67.6   0.1   2.8e-22   1.2e-18       1      63 []      55     117 ..      55     117 .. 0.98

  Alignments for each domain:
  == domain 1  score: 67.6 bits;  conditional E-value: 2.8e-22
    CTD_bind   1 kLnllYLaNdvlqnskrkqkdefapaFapvlpeafadaykkapekikkklkrllniWeernvf 63 
                 kLnl+YLaN+v q+sk ++kd+f+ aF+p++ ea a ayk+a+++i++k++r++++W++r+vf
  EEA23101.1  55 KLNLIYLANEVAQQSKARRKDDFIIAFSPIIAEATAVAYKGASSEIQQKIRRVVEVWRQRGVF 117
                 9**************99999********************99********************9 PP

>> DUF3277  Protein of unknown function (DUF3277)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.3   0.0   2.5e-05      0.11      52     113 ..      30      95 ..      12     105 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.3 bits;  conditional E-value: 2.5e-05
     DUF3277  52 vmhslhagksGtitirllktspvnkkLqalyna....qslssaewgsnvitirntaagdvivarsv 113
                  +h +ha+++ ++ ++ l+ sp+nkkL+ +y a    q++++ +  + +i+++   a  ++va ++
  EEA23101.1  30 MFHRRHADRTVQLWLQKLRDSPANKKLNLIYLAnevaQQSKARRKDDFIIAFSPIIAEATAVAYKG 95 
                 56999**************************65323344444455555666666666666666555 PP

>> CTK3  CTD kinase subunit gamma CTK3
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.2   0.1   3.1e-05      0.14      13     121 ..      11     116 ..       7     118 .. 0.85

  Alignments for each domain:
  == domain 1  score: 12.2 bits;  conditional E-value: 3.1e-05
                 HHTT--SSGGGTHHHHHHHHHTGGGHHHHHHHHHHHHHHS-HHHHHHHHHHHHHHHHHHHHTT--S..THHHHHHHTHHHHHHHHS-HHHHHHHHHHHH CS
        CTK3  13 lLrkLtasvqslqkaaqfAlknkdkeedlfscileqlesadlNtranilyfidllleeslkegqsekspYveslkrdilklvdsvvPgsgaaNlksvrk 111
                  L+ L+  ++ +  +aq+ + ++ +++  ++  l++l ++  N + n++y+ + + ++s +  ++   +++  ++  i +       g+ +   +++r+
  EEA23101.1  11 KLSALNETQEGIVTVAQWVMFHRRHADRTVQLWLQKLRDSPANKKLNLIYLANEVAQQSKARRKD---DFIIAFSPIIAEATAVAYKGASSEIQQKIRR 106
                 58999**********************************************99988887666555...8999999888777655555777777788899 PP

                 HHHHHHHTTS CS
        CTK3 112 ilkslklksl 121
                 +++ ++++ +
  EEA23101.1 107 VVEVWRQRGV 116
                 9999999876 PP

>> TetR_C_4  YsiA-like protein, C-terminal region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.7   0.0       1.4   6.1e+03     106     116 ..      24      34 ..      22      42 .. 0.81
   2 ?   -0.7   0.0      0.33   1.5e+03      44      69 ..      86     111 ..      78     127 .. 0.81
   3 ?    9.0   0.3   0.00032       1.4      11      61 ..     219     267 ..     209     279 .. 0.81

  Alignments for each domain:
  == domain 1  score: -2.7 bits;  conditional E-value: 1.4
                 HHHHHHHTTT- CS
    TetR_C_4 106 vvtnWvmkdqk 116
                 +v++Wvm + +
  EEA23101.1  24 TVAQWVMFHRR 34 
                 7999***7655 PP

  == domain 2  score: -0.7 bits;  conditional E-value: 0.33
                 HHHHHTTCCGSSHHHHHHHHHHHHHH CS
    TetR_C_4  44 aivtqlelrqsnlelrlkinevlkgy 69 
                 a  t +  + + +e+++ki  v+  +
  EEA23101.1  86 AEATAVAYKGASSEIQQKIRRVVEVW 111
                 55677777888999999999998766 PP

  == domain 3  score: 9.0 bits;  conditional E-value: 0.00032
                 HHHHHHTT-SSHHHHHHHHHHHHHHHHHC-HHHHHHHHTTCCGSSHHHHHH CS
    TetR_C_4  11 kikeeikekesaeeklkllvekhfsqlsadkelaivtqlelrqsnlelrlk 61 
                  ++e ik+++   e l++++e+  ++ls   e a++tq+  r+s++e+r++
  EEA23101.1 219 SVSEIIKSRQALMEGLEKMLETNRTALSR--ETALLTQMGERKSDTEMRKR 267
                 56677888889999999999999998886..56889*************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (366 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       898  (0.0500865); expected 358.6 (0.02)
Passed bias filter:                      613  (0.0341904); expected 358.6 (0.02)
Passed Vit filter:                        54  (0.00301188); expected 17.9 (0.001)
Passed Fwd filter:                         4  (0.000223102); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.56u 0.31s 00:00:00.87 Elapsed: 00:00:00.48
# Mc/sec: 2306.90
//
Query:       EEA23102.1  [L=240]
Description: clathrin light chain [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
      9e-75  251.7   2.1      1e-74  251.5   2.1    1.0  1  Clathrin_lg_ch  Clathrin light chain


Domain annotation for each model (and alignments):
>> Clathrin_lg_ch  Clathrin light chain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  251.5   2.1   5.6e-79     1e-74       1     230 []       1     237 [.       1     237 [. 0.92

  Alignments for each domain:
  == domain 1  score: 251.5 bits;  conditional E-value: 5.6e-79
  Clathrin_lg_ch   1 maDkFpsledegaeteasaaaeedpaadFLarekaelgdda.qfateqdeealleaeeeeddllgaa....aangeedeeidefesqfpaieaad 90 
                     maD+Fpsled ++ +++  ++++++++dFLare+a+lgdda qfat++d++a+     e+ddllg++    ++     +ei+ fes+fpai++++
      EEA23102.1   1 MADRFPSLEDFNEGQTEVVNNDAADTDDFLARERAALGDDAdQFATPNDQAAT----VEDDDLLGGNdyvpQQ--GGAAEISGFESSFPAIDTQN 89 
                     9********65555555678999999************************996....3468899888765333..469***************** PP

  Clathrin_lg_ch  91 eqvapegtites.....eess..saeeeeeeepesirkWReerkkeieerdeasekkkeetkekAkkeiddfyenynekkektkaqnrkeeeefl 178
                     e+vap+gtit++     +  +  s+++++eee++++++WR +r++++++r e s++kk++t++kA+++iddfy +y ++ +k++aq+rke+eefl
      EEA23102.1  90 EAVAPGGTITGTgspfpA--TgySSYTQPEEESDAVKEWRARRDADLARRSETSAEKKAATIKKAQEDIDDFYVSYGNRSDKARAQTRKEAEEFL 182
                     ************886533..256999********************************************************************* PP

  Clathrin_lg_ch 179 kerddtspgGteWeRvakLvdfnpkss...ksgkdksRfrelLlsLKqdekaPga 230
                     ++r+dts+gGt+WeR+akLvd+++k+    +sg++k+RfrelLl+L++d +aPga
      EEA23102.1 183 ANREDTSAGGTSWERIAKLVDISGKGVkggASGSGKERFRELLLDLRKDGNAPGA 237
                     **************************99999**********************97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (240 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       857  (0.0477997); expected 358.6 (0.02)
Passed bias filter:                      463  (0.0258241); expected 358.6 (0.02)
Passed Vit filter:                        38  (0.00211947); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.48u 0.25s 00:00:00.73 Elapsed: 00:00:00.43
# Mc/sec: 1694.60
//
Query:       EEA23103.1  [L=492]
Description: Hsp90 co-chaperone Cdc37 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.5e-50  171.4   7.1    3.9e-50  170.1   2.7    2.9  2  CDC37_N         Cdc37 N terminal kinase binding
    5.9e-41  139.1   0.2    3.7e-40  136.5   0.0    2.2  2  CDC37_M         Cdc37 Hsp90 binding domain
    1.6e-36  124.4   1.0    1.6e-36  124.4   1.0    2.7  3  CDC37_C         Cdc37 C terminal domain
  ------ inclusion threshold ------
      0.053   13.4   0.1       0.19   11.7   0.1    2.0  1  Thiamine_BP     Thiamine-binding protein
      0.054   14.2   0.7          3    8.5   0.2    3.1  2  Cytochrom_B562  Cytochrome b562
      0.072   13.4   0.0       0.17   12.1   0.0    1.7  1  SusD-like_3     Starch-binding associating with outer membran


Domain annotation for each model (and alignments):
>> CDC37_N  Cdc37 N terminal kinase binding
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  170.1   2.7   1.3e-53   3.9e-50       1     128 [.       2     136 ..       2     137 .. 0.94
   2 ?    2.0   0.1      0.12   3.6e+02      58     104 ..     155     201 ..     145     224 .. 0.57

  Alignments for each domain:
  == domain 1  score: 170.1 bits;  conditional E-value: 1.3e-53
     CDC37_N   1 pldYskWDklELSDDsDievHPNVDkrsfirwKqrdihekreqrkaeikklklereindkllkridkllealkekevee...eevvfkalnesleekke 96 
                 +ldYskWD+lELSDDsDievHPNVDkrsfir+Kq++ih++r qr++ei++lk+er ind+ll+ridkll al+++e+++   ee+vf++l es+   ++
  EEA23103.1   2 VLDYSKWDALELSDDSDIEVHPNVDKRSFIRAKQNQIHQQRMQRRHEIETLKYERIINDGLLERIDKLLGALRQHEDSSrnpEELVFQSLIESA--GDP 98 
                 59***************************************************************************9999999**********..566 PP

     CDC37_N  97 kedkpkaek......eeeqptydemleklldqvkkelk 128
                  +d+p+a++      e+eqp+y++m+++l+dqvkke+ 
  EEA23103.1  99 AKDQPPAPPagiythEKEQPKYSQMMSSLVDQVKKEIT 136
                 688888886778886699*****************986 PP

  == domain 2  score: 2.0 bits;  conditional E-value: 0.12
     CDC37_N  58 ndkllkridkllealkekevee.eevvfkalnesleekkekedkpkae 104
                 +dk+l+  ++ll++l+e e+ee ++++ ++++  + +++   ++++++
  EEA23103.1 155 KDKVLALQQELLQKLTELEKEEaSKITSDSIRTGF-DSSFVAKSDPKP 201
                 56677777777777777666663444455555555.333333333333 PP

>> CDC37_M  Cdc37 Hsp90 binding domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   0.0      0.34     1e+03      49      68 ..     157     176 ..     117     203 .. 0.70
   2 !  136.5   0.0   1.2e-43   3.7e-40       2     116 ..     254     361 ..     253     363 .. 0.98

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.34
     CDC37_M  49 kqvvhqslllqyireLakln 68 
                 k ++ q +llq + eL k +
  EEA23103.1 157 KVLALQQELLQKLTELEKEE 176
                 34456888999999993322 PP

  == domain 2  score: 136.5 bits;  conditional E-value: 1.2e-43
     CDC37_M   2 FakiklgdykkseefllkhpeilseqqkdaLlmeafdaqlegkekkakqvvhqslllqyireLaklnkeglknviklFfkkiktkshqakklFledvee 100
                  aki+++dyk+  +f++ +p++++e+++d+Ll+eaf++q++gk ++a+q+vh++lllqy+r+L      g+ ++i+lFfk+i+tk+hqa++lF +dv+e
  EEA23103.1 254 LAKIPMTDYKALFQFISANPDVVAEKETDGLLVEAFNSQMDGKAEYARQCVHHGLLLQYCRSL------GR-DGISLFFKRITTKDHQAATLFRNDVNE 345
                 79*************************************************************......88.*************************** PP

     CDC37_M 101 tynriktRakiikkeq 116
                 tyn+ik Ra++++k++
  EEA23103.1 346 TYNKIKIRAAELAKNR 361
                 ************9987 PP

>> CDC37_C  Cdc37 C terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.9   0.1       2.6   7.9e+03      66      82 ..     162     178 ..     154     184 .. 0.49
   2 ?   -0.2   0.0      0.38   1.1e+03      37      53 ..     342     358 ..     339     379 .. 0.79
   3 !  124.4   1.0   5.3e-40   1.6e-36       2      95 ..     388     481 ..     387     484 .. 0.95

  Alignments for each domain:
  == domain 1  score: -2.9 bits;  conditional E-value: 2.6
     CDC37_C  66 eellvdatteegekelk 82 
                 +++l+++ te +++e++
  EEA23103.1 162 QQELLQKLTELEKEEAS 178
                 44444444443333333 PP

  == domain 2  score: -0.2 bits;  conditional E-value: 0.38
     CDC37_C  37 evnkvlakmkveeAeei 53 
                  vn++ +k+k+  Ae  
  EEA23103.1 342 DVNETYNKIKIRAAELA 358
                 79***********9965 PP

  == domain 3  score: 124.4 bits;  conditional E-value: 5.3e-40
     CDC37_C   2 lPdadsedpeeqkkvevFeklppelqkAlktksLdevnkvlakmkveeAeeilellgeagilsleellvdatteegekelkeleeekkekkkee 95 
                 +P+ads++pee++++++F+++pp lq+Al++ sLdevnkvl+km+veeAeei+e+lge+g+ls+ee++vdatteeg+k+l+e+e+e k++++ e
  EEA23103.1 388 IPPADSTNPEEIEARKIFDSFPPGLQRALQSASLDEVNKVLGKMSVEEAEEIVEKLGEGGMLSVEEGIVDATTEEGRKKLEEIEAEGKREREIE 481
                 8*************************************************************************************99776544 PP

>> Thiamine_BP  Thiamine-binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.1   6.3e-05      0.19      12      67 ..     121     176 ..     117     198 .. 0.82

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 6.3e-05
                  SSGHHHHHHHHHHHHHTTSSEEEEETTEEEEEEEHHHHHHHHHHHHHHHHCTTSSE CS
  Thiamine_BP  12 gesvskyVakvvevlkesglkyeltpmgTtiegeldevmevvkkahealfeaGakR 67 
                  ++ +s+ V++v + + es+ ++  +++ T ++g  d+v+++ +++ ++l e + ++
   EEA23103.1 121 SQMMSSLVDQVKKEITESKSENGFKAYITGVQGHKDKVLALQQELLQKLTELEKEE 176
                  57799***********************************9999988888775544 PP

>> Cytochrom_B562  Cytochrome b562
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.5   0.2     0.001         3      35      74 ..      95     137 ..      63     181 .. 0.81
   2 ?    2.9   0.0     0.057   1.7e+02      39      91 ..     391     444 ..     342     446 .. 0.78

  Alignments for each domain:
  == domain 1  score: 8.5 bits;  conditional E-value: 0.001
  Cytochrom_B562  35 aaedakeatpsklek...dseeqkdYqeGldklidqldkaeal 74 
                     a + ak + p+ +++    ++eq +Y + ++ l+dq++k  ++
      EEA23103.1  95 AGDPAKDQPPAPPAGiytHEKEQPKYSQMMSSLVDQVKKEITE 137
                     44557777777777799999*****************986554 PP

  == domain 2  score: 2.9 bits;  conditional E-value: 0.057
  Cytochrom_B562  39 akeatpsklekdseeqkdYqeGldklid..qldkaealakagkleeakaalkelk 91 
                     a +++p+++e  ++ ++ +  Gl+  ++   ld++++ + +  +eea++++++l 
      EEA23103.1 391 ADSTNPEEIE-ARKIFDSFPPGLQRALQsaSLDEVNKVLGKMSVEEAEEIVEKLG 444
                     4455555555.77888889999998765226999999999999******999986 PP

>> SusD-like_3  Starch-binding associating with outer membrane
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.1   0.0   5.9e-05      0.17      70     161 ..     254     359 ..     198     376 .. 0.72

  Alignments for each domain:
  == domain 1  score: 12.1 bits;  conditional E-value: 5.9e-05
  SusD-like_3  70 taatktnlWsnlYkvIfdaNivLeele..kekaeeelkqvkGeAlflRAyayflLvnvfg............kvpyttaseaeakleraTvqevydkI 153
                   a+ + +++++l++ I+    v  e e      e+  +q+ G+A   R   +  L+ +++            k  +tt+  + a+l r+ v+e+y+kI
   EEA23103.1 254 LAKIPMTDYKALFQFISANPDVVAEKEtdGLLVEAFNSQMDGKAEYARQCVHHGLLLQYCrslgrdgislffK-RITTKDHQAATLFRNDVNETYNKI 350
                  45666778888888776654444443422222233668899******************99999998876665.55566666789************9 PP

  SusD-like_3 154 .ikDlkeAi 161
                   i+  + A+
   EEA23103.1 351 kIRAAELAK 359
                  445555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (492 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                      1235  (0.0688828); expected 358.6 (0.02)
Passed bias filter:                      646  (0.036031); expected 358.6 (0.02)
Passed Vit filter:                        59  (0.00329076); expected 17.9 (0.001)
Passed Fwd filter:                         7  (0.000390429); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.57u 0.30s 00:00:00.86 Elapsed: 00:00:00.43
# Mc/sec: 3414.97
//
Query:       EEA23104.1  [L=783]
Description: ABC multidrug transporter Mdr2 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    9.4e-50  169.8   8.3    1.2e-49  169.4   8.3    1.2  1  ABC_membrane  ABC transporter transmembrane region
    1.2e-35  123.0   0.0    4.8e-35  121.1   0.0    2.0  2  ABC_tran      ABC transporter
    1.8e-05   24.3   0.0     0.0014   18.1   0.0    2.3  2  SMC_N         RecF/RecN/SMC N terminal domain
      0.004   17.4   0.1      0.038   14.3   0.1    2.4  1  AAA_22        AAA domain
      0.007   16.8   0.1        0.1   13.0   0.1    2.4  1  AAA           ATPase family associated with various cellular 
     0.0075   16.7   0.0      0.026   14.9   0.0    1.9  1  AAA_16        AAA ATPase domain
  ------ inclusion threshold ------
       0.01   15.5   0.0      0.029   14.1   0.0    1.8  1  AAA_29        P-loop containing region of AAA domain
      0.069   12.9   0.1       0.59    9.8   0.0    2.3  2  IstB_IS21     IstB-like ATP binding protein
       0.07   12.8   0.0       0.23   11.2   0.0    1.9  1  AAA_30        AAA domain
       0.13   12.2   0.1       0.81    9.7   0.0    2.2  2  AAA_5         AAA domain (dynein-related subfamily)
       0.18   12.0   0.5        2.2    8.6   0.5    2.6  1  SbcCD_C       Putative exonuclease SbcCD, C subunit
       0.48   10.9   4.1       0.73   10.3   0.1    2.7  3  AAA_23        AAA domain


Domain annotation for each model (and alignments):
>> ABC_membrane  ABC transporter transmembrane region
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  169.4   8.3   8.4e-53   1.2e-49       2     268 ..     170     439 ..     169     445 .. 0.98

  Alignments for each domain:
  == domain 1  score: 169.4 bits;  conditional E-value: 8.4e-53
                   HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSTCCHH...HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSTHHHHHHS CS
  ABC_membrane   2 iliillailagvlsplfplvlgrildtlldkgdpet...ealnvysllllllglaqfilallqsyllnvtgerlskrlrrklfkkilrqpmsffdtn 95 
                    l++++++++  + + +p+ +g+i+d  ++  d+e    + + +++ +l+++  + +++++++  +l ++ger++ r r+klf++ + q+ +ffd n
    EEA23104.1 170 GLAFFFLLISSSITMSIPFSIGKIMDLATKGEDAEGlfgMSMPMFYGALAGIICVGAAANYGRIIILRIVGERVVARQRSKLFRRTFVQDAEFFDAN 266
                   689**************************9777766************************************************************* PP

                   CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHH CS
  ABC_membrane  96 svGellsrltndvsklrdglgeklglffqslltfvgglivmfylgwkltlvllailpliilvsaviakilkklkkkeqkavakassvaeEslsgirt 192
                   +vG+l+srl++d+  +  +++++l++ ++s++++ +g++ m y++ kl+ vl  +lp i + ++++++++++l++k qk+++ ++++aeE l +++t
    EEA23104.1 267 RVGDLISRLSSDTLIVGKSITQNLSDGLRSIVSCTAGFGAMAYVSLKLSSVLALLLPPIGVAAFFYGRTIRNLSRKIQKNLGTLTKIAEERLGNVKT 363
                   ************************************************************************************************* PP

                   HHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSTHHHHHHHHHHHH CS
  ABC_membrane 193 VkafgreeyflekfekaleeakkagikkaianglligitqllgllsyalalwfGttlvisgelsvgdlvvflslfa 268
                    +af++e  ++ ++++++++  + g+k  ++++ +++ t l+g+  +++ l++G+ lv+sg +++g+l+ fl++  
    EEA23104.1 364 SQAFAAEVSEVARYNNQVKKIFELGKKESLISASFFSSTGLMGNMTILILLYVGGGLVQSGGITLGELTSFLMYTV 439
                   *************************************************************************986 PP

>> ABC_tran  ABC transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.2   0.0       3.6   5.4e+03      64     117 ..     245     298 ..     237     302 .. 0.64
   2 !  121.1   0.0   3.2e-38   4.8e-35       2     137 .]     509     656 ..     508     656 .. 0.90

  Alignments for each domain:
  == domain 1  score: -2.2 bits;  conditional E-value: 3.6
                 E-SS--S-TTSBHHHH..HHHTCHHHHHHHSTTGGTTCBGESTTS.GGS-HHHHHHH CS
                 xxxxxxxxxxxxxxxx..xxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxx RF
    ABC_tran  64 lpqepqlfpeltvren..esdeeiekalsklglkelkdtvvkssp.ssLSgGqkqrv 117
                   q ++lf+++ v++    + +++ +++s+l+ +     +v++s  ++LS G ++ v
  EEA23104.1 245 ARQRSKLFRRTFVQDAefFDANRVGDLISRLSSDT---LIVGKSItQNLSDGLRSIV 298
                 55667777777776665555556777777776554...3444444489999988766 PP

  == domain 2  score: 121.1 bits;  conditional E-value: 3.2e-38
                 EEEEEEEETTSEEEEEESTTSSHHHHHHHHTTSS--SEEEEEETTCEGGGB-HHHCCHCEEEE-SS--S-TTSBHHHH.......HHHTCHHHHHHHST CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.......xxxxxxxxxxxxxx RF
    ABC_tran   2 knvslklkegekvaivGenGaGKStLlkllagllkpteGeilldgkdlkeqeleslrkeigvlpqepqlfpeltvren.......esdeeiekalsklg 93 
                 +++++++ +g+ vaivG++G GKSt+++ll++ ++p +G+il++gkd+++ + + lr++igv++qep lf+++ ++en       + ++ei +a+++ +
  EEA23104.1 509 EDLNFEIPQGSNVAIVGPSGGGKSTIASLLLRFYNPVSGRILINGKDISKMNAKALRRKIGVVSQEPVLFSGT-IAENiaygvpgATKAEIVAAARQAN 606
                 689**********************************************************************.99999*****966666666666666 PP

                 TGG......TTCBGESTTSGGS-HHHHHHHHHHHHHHHTSSEEEEESTTT CS
                 xxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF
    ABC_tran  94 lke......lkdtvvksspssLSgGqkqrvalarallkkpkllllDEpta 137
                  +         +t+v+ ++++LSgGqkqr+a+aral+k+p++l+lDE+t+
  EEA23104.1 607 CQFisdfpsGLETNVGPRGAQLSGGQKQRIAIARALIKNPDILILDEATS 656
                 5554455555678888888*****************************96 PP

>> SMC_N  RecF/RecN/SMC N terminal domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    3.5   0.5     0.028        42      26      41 ..     520     535 ..     508     542 .. 0.81
   2 !   18.1   0.0   9.4e-07    0.0014     109     210 ..     547     698 ..     535     706 .. 0.87

  Alignments for each domain:
  == domain 1  score: 3.5 bits;  conditional E-value: 0.028
                 EEEEEESTTSSHHHHH CS
                 xxxxxxxxxxxxxxxx RF
       SMC_N  26 ftaivGpNGSGKsnll 41 
                   aivGp G GKs + 
  EEA23104.1 520 NVAIVGPSGGGKSTIA 535
                 468**********986 PP

  == domain 2  score: 18.1 bits;  conditional E-value: 9.4e-07
                 EEEEETTEEE-HHHHHHHHHCTT-STT.....................................................CS-HHHHHHHHHHHHHHHH CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxx.....................................................xxxxxxxxxxxxxxxxxxx RF
       SMC_N 109 seykingkevtkkevsellesagiske.....................................................lLSgGektLvalaLlfAiq 154
                  ++ ingk+++k + + l ++ g+ ++                                                     +LSgG+k+ +a+a      
  EEA23104.1 547 GRILINGKDISKMNAKALRRKIGVVSQepvlfsgtiaeniaygvpgatkaeivaaarqancqfisdfpsgletnvgprgaQLSGGQKQRIAIARA---- 641
                 56789999999999999999999998899***********************************************************9888654.... PP

                 CCS--SEEEECTTTTTS-HHHHHHHHHHHHH.HCTTSEEEEE-SSHHHCCC-SCEEE CS
                 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxx RF
       SMC_N 155 kvkpaplyllDeidaaLDeknvkkvaellke.ksknaQfivislreemlekadklvg 210
                  +k   + +lDe  +aLD++  + v + l +  + n   i i++r  +++++d+++ 
  EEA23104.1 642 LIKNPDILILDEATSALDAESETLVNSALATlLRGNNTTISIAHRLSTIKRSDTIIV 698
                 45666799****************999998515667889999***999999998875 PP

>> AAA_22  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.1   2.5e-05     0.038       6     107 ..     519     664 ..     516     687 .. 0.58

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 2.5e-05
      AAA_22   6 gilvvtGesGtGKTtllrrlleqldeeakaee...............erpevvfvtlpsstsskdllrellralglelka................... 70 
                 + ++++G+sG GK+t +  ll+ ++ ++                   +                    ++    +++                      
  EEA23104.1 519 SNVAIVGPSGGGKSTIASLLLRFYNPVSGRILingkdiskmnakalrR--------------------KIGVVSQEPVLFsgtiaeniaygvpgatkae 597
                 5689********************876554446555555544444431....................3333222222223333333333333344446 PP

      AAA_22  71 ........................erlsseell.ealeqalrarav...ielliiDEaqh.lr..see 107
                                            +  +l   + ++ + ara    + +li+DEa   l+  se+
  EEA23104.1 598 ivaaarqancqfisdfpsgletnvG-PRGAQLSgGQKQRIAIARALiknPDILILDEATSaLDaeSET 664
                 6667777777777777766666642.344444446666666666666677888888888877665333 PP

>> AAA  ATPase family associated with various cellular activities (AAA)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   13.0   0.1   6.9e-05       0.1       2      97 ..     522     678 ..     521     702 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 6.9e-05
                 EEESSTTSSHHHHHHHHHHHH..........THEEEEEETTTCSSS..................................................... CS
         AAA   2 llyGppGtGKTllakavakel..........gvefleisgsellsk..................................................... 37 
                  ++Gp G GK+++a+ + +            g ++ +++++ l+ k                                                     
  EEA23104.1 522 AIVGPSGGGKSTIASLLLRFYnpvsgrilinGKDISKMNAKALRRKigvvsqepvlfsgtiaeniaygvpgatkaeivaaarqancqfisdfpsgletn 620
                 579***************99733333333334667777777777779999999*********************************************9 PP

                 .....STTHHHHHHHHHHHHHHHTSTSEEEEEETGGGHHHHHTTCCCHHHHHHHHHHHHHHHHTT CS
         AAA  38 .....yvgesekkirelfkeakekakpsilfiDEidalaksrsgseseeeervvnqLlteldgvk 97 
                       +  + +k r  +++a  k+ p il++DE+ +   ++      +e+ v ++L t l g +
  EEA23104.1 621 vgprgAQLSGGQKQRIAIARALIKN-PDILILDEATSALDAE------SETLVNSALATLLRGNN 678
                 9999877777788888888887777.9**********99999......44455555555555544 PP

>> AAA_16  AAA ATPase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   1.8e-05     0.026      23     154 ..     517     665 ..     508     682 .. 0.46

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 1.8e-05
      AAA_16  23 rpelvllsGesGvGKsslvrellralekd.....................ggiflrgkcdql....esaipysalaqalareellrqlldeaesaelea 96 
                 ++++v ++G+sG GKs+++  llr ++                       ++ +++++ + +     ++i+y               +  ++++  ++a
  EEA23104.1 517 QGSNVAIVGPSGGGKSTIASLLLRFYNPVsgrilingkdiskmnakalrrKIGVVSQEPVLFsgtiAENIAY--------------GVPGATKAEIVAA 601
                 5689*******************8666554222222333333333333221222222222221111111222..............1111111111111 PP

      AAA_16  97 wrekleeala....................avpelagaeasrllellkrllallsrderplvlvlDdlq.wadeaslql 154
                 +        +                     +++l+g +++r++ + ++l+      + p +l+lD++   +d++s +l
  EEA23104.1 602 A--------RqancqfisdfpsgletnvgpRGAQLSGGQKQRIAIA-RALI------KNPDILILDEATsALDAESETL 665
                 1........1222222234444444433355555555555555444.3333......3355777777664445555555 PP

>> AAA_29  P-loop containing region of AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.0     2e-05     0.029      12      38 ..     508     534 ..     506     539 .. 0.82

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 2e-05
      AAA_29  12 fdghtieidlkg.atlltGpsGsGKSTl 38 
                 f++  +ei  +g ++ ++GpsG GKST+
  EEA23104.1 508 FEDLNFEIP-QGsNVAIVGPSGGGKSTI 534
                 555667786.555**************8 PP

>> IstB_IS21  IstB-like ATP binding protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.8   0.0    0.0004      0.59      44      65 ..     515     536 ..     491     540 .. 0.83
   2 ?   -0.3   0.1      0.53   7.9e+02      98     127 ..     635     663 ..     626     692 .. 0.69

  Alignments for each domain:
  == domain 1  score: 9.8 bits;  conditional E-value: 0.0004
   IstB_IS21  44 iekkenivllGpsGvGKshlai 65 
                 i +  n++++GpsG GKs +a 
  EEA23104.1 515 IPQGSNVAIVGPSGGGKSTIAS 536
                 66789*************9986 PP

  == domain 2  score: -0.3 bits;  conditional E-value: 0.53
   IstB_IS21  98 klaralkrllkvdllilDdlgllpldqaea 127
                 ++a a + + ++d+lilD+     ld +++
  EEA23104.1 635 RIAIARALIKNPDILILDEAT-SALDAESE 663
                 444444556677******964.45555555 PP

>> AAA_30  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.2   0.0   0.00015      0.23      21     112 ..     521     669 ..     515     676 .. 0.73

  Alignments for each domain:
  == domain 1  score: 11.2 bits;  conditional E-value: 0.00015
      AAA_30  21 avltGpAGtGKttalkalreaweaaggrvi..glAptgkaAkvLae....................elgieastiakllkrlk................ 81 
                 ++++Gp G GK+t+ + l + ++   gr++  g   ++  Ak+L++                    + g++++t a+++ + +                
  EEA23104.1 521 VAIVGPSGGGKSTIASLLLRFYNPVSGRILinGKDISKMNAKALRRkigvvsqepvlfsgtiaeniAYGVPGATKAEIVAAARqancqfisdfpsglet 619
                 689********************99666662356678999999**822222222222222222233334455555555544449999999999999999 PP

      AAA_30  82 ...................grarlepgtllivDEagmvdtkqlaallkaa 112
                                    +ra +++ ++li DEa  +  ++ ++l+++a
  EEA23104.1 620 nvgprgaqlsggqkqriaiARALIKNPDILILDEATSALDAESETLVNSA 669
                 99999999999999999997778888899999999998888888887776 PP

>> AAA_5  AAA domain (dynein-related subfamily)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.7   0.0   0.00054      0.81       2      24 ..     521     543 ..     520     566 .. 0.82
   2 ?   -0.9   0.0      0.99   1.5e+03      63      81 ..     643     661 ..     621     707 .. 0.74

  Alignments for each domain:
  == domain 1  score: 9.7 bits;  conditional E-value: 0.00054
                 EEEE--SSSSHHHHHHHGGGGBS CS
       AAA_5   2 vlLvGppGtgKselaerlaaaln 24 
                 v +vGp+G gKs++a  l++++n
  EEA23104.1 521 VAIVGPSGGGKSTIASLLLRFYN 543
                 779****************9994 PP

  == domain 2  score: -0.9 bits;  conditional E-value: 0.99
                 --G-SEEEEESGGG--HHH CS
       AAA_5  63 aregeilvlDEveraesev 81 
                 +++++il+lDE + a ++ 
  EEA23104.1 643 IKNPDILILDEATSALDAE 661
                 3489999999999876544 PP

>> SbcCD_C  Putative exonuclease SbcCD, C subunit
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.6   0.5    0.0015       2.2      62      82 ..     644     664 ..     608     672 .. 0.69

  Alignments for each domain:
  == domain 1  score: 8.6 bits;  conditional E-value: 0.0015
     SbcCD_C  62 palrlvfLDEAFsklDeesia 82 
                 +++++++LDEA s lD+es +
  EEA23104.1 644 KNPDILILDEATSALDAESET 664
                 3589************99865 PP

>> AAA_23  AAA domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.3   0.1         7   1.1e+04     141     142 ..     356     357 ..     329     396 .. 0.38
   2 ?   10.3   0.1   0.00049      0.73      10      36 ..     508     535 ..     504     539 .. 0.76
   3 ?    1.0   0.1      0.34     5e+02     153     170 ..     749     766 ..     661     780 .. 0.70

  Alignments for each domain:
  == domain 1  score: -3.3 bits;  conditional E-value: 7
      AAA_23 141 er 142
                 er
  EEA23104.1 356 ER 357
                 11 PP

  == domain 2  score: 10.3 bits;  conditional E-value: 0.00049
      AAA_23  10 frdqeidFskglt.lItGpNGaGKTTil 36 
                 f+d +++  +g + +I+Gp G GK+Ti 
  EEA23104.1 508 FEDLNFEIPQGSNvAIVGPSGGGKSTIA 535
                 667777775554428***********96 PP

  == domain 3  score: 1.0 bits;  conditional E-value: 0.34
      AAA_23 153 erleelekeleeledekk 170
                 e+leele+e++e+e e++
  EEA23104.1 749 EQLEELEREQRENESEIE 766
                 244444444444333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (783 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       854  (0.0476323); expected 358.6 (0.02)
Passed bias filter:                      631  (0.0351944); expected 358.6 (0.02)
Passed Vit filter:                        88  (0.00490825); expected 17.9 (0.001)
Passed Fwd filter:                        12  (0.000669307); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.76u 0.30s 00:00:01.06 Elapsed: 00:00:00.45
# Mc/sec: 5245.14
//
Query:       EEA23105.1  [L=487]
Description: Nucleoside transporter family [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model           Description
    ------- ------ -----    ------- ------ -----   ---- --  --------        -----------
    4.1e-43  147.9   7.8    4.1e-43  147.9   7.8    2.1  2  Nucleoside_tran  Nucleoside transporter
    0.00052   19.0  33.9    0.00081   18.4   2.6    3.4  3  MFS_1            Major Facilitator Superfamily
  ------ inclusion threshold ------
      0.031   14.2  14.7        0.2   11.6   0.0    4.5  4  DUF2975          Protein of unknown function (DUF2975)
        1.1    9.1   0.0        1.1    9.1   0.0    2.5  3  DUF1980          Domain of unknown function (DUF1980)


Domain annotation for each model (and alignments):
>> Nucleoside_tran  Nucleoside transporter
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.6       1.3   5.9e+03      73      89 ..     111     127 ..      99     152 .. 0.52
   2 !  147.9   7.8   9.2e-47   4.1e-43       1     307 [.     165     484 ..     164     486 .. 0.80

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 1.3
  Nucleoside_tran  73 vivcvilllvlkklefy 89 
                       ++cv++l  l++ + y
       EEA23105.1 111 NLLCVLVLAKLQQNASY 127
                      34444444433333322 PP

  == domain 2  score: 147.9 bits;  conditional E-value: 9.2e-47
  Nucleoside_tran   1 lakvvlinsfnallqnslfglagelps.eYtqavliGqalaGvlvslvmilavasnse...............lkesallYFivsivvvivcvi 78 
                      + +v   +++ ++ qn++f+ ++ ++  eYtqa+++Gq++aGvl+ +v+i++ a++ +                 +sal YF  +++v +v++ 
       EEA23105.1 165 MTMVLGASFAVGMNQNGVFAYVSGFGRpEYTQAIMAGQGIAGVLPCIVQIITNAAGGSrrhdgdhqknddgdeFYKSALTYFLFAVLVTLVALF 258
                      45666667799**************9769***********************99988778999999999999999****************999 PP

  Nucleoside_tran  79 lllvlkklefykeykqlklegslletkeelrqekeeeseskvkltaekskegeenvfvllkvilakikvlalsvvlvftvtlsvfpavtaevks 172
                      ++  l        +  ++       ++++  ++  ++ ++ +  +++          v l+ ++  +k lal v l ftvt  ++p++t++v+s
       EEA23105.1 259 SFVQLMSRTAGPRWFIREF---RAIQNAHTMSDATNPAPE-LPAPTH--------KTVGLWRLFLRLKWLALAVYLCFTVT-MIYPVFTVKVQS 339
                      9988766554444444441...111134444444445544.222222........2356799****************776.589********* PP

  Nucleoside_tran 173 silptkee.yfip.v...llfllfNlfdllGrvlaavimwpdq..dsrllvvlvllRllfiplfllcnakpq.sr.alpvlfesdllfill.ml 256
                         p  ++ +f p +   l fl +N++dl+Gr+   v+ +      +r ++  ++ Rl+fip++l+cn++          +++sd +++++ +l
       EEA23105.1 340 VHNPATRSrIFEPeLfipLAFLFWNMGDLIGRMSPIVPVLARAagYPRAVFAFSVSRLIFIPMYLACNIRSGrDAtGNGAVINSDFFYLFVvQL 433
                      98877555566552222257************988888887656689***********************764332444566677766654256 PP

  Nucleoside_tran 257 lfalsnGYlasllmmlaPkkvkpkeketAgaltsfflvlGLalGavlsflf 307
                       f+l+nG+l s++mm a + +  +e+e+Ag ++s++lv GLa+G++lsf+f
       EEA23105.1 434 GFGLTNGFLGSVCMMGAGQYITVDEREAAGGFMSMMLVAGLATGSLLSFFF 484
                      699**********************************************99 PP

>> MFS_1  Major Facilitator Superfamily
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   2.6   1.8e-07   0.00081     205     347 ..      53     208 ..      15     216 .. 0.67
   2 !    4.1   9.4    0.0041        19     154     274 ..     246     375 ..     237     412 .. 0.53
   3 !    4.2  11.1    0.0038        17      82     146 ..     419     486 ..     373     487 .] 0.76

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 1.8e-07
       MFS_1 205 kdpvlw.....illialllfffgfsglltllplylqevlgls.....glllaglllallalvgailallagrlsdrlgrrrrlllallllllaalglal 293
                 k+p+ w     +ll+++++ + +++++l+  p + + ++  +      + ++   l+++ + ++   l++++l +  +  +r+ ++l++l++++++ a+
  EEA23105.1  53 KKPFSWhdytvFLLLGVAMLW-AWNMFLAAAPYF-RRRFEKNpwaleHYESSI--LSVSTITNLLCVLVLAKLQQNASYPIRIAVSLVILTAVFALQAM 147
                 444446666643444444444.9999*******8.999998899997555555..88888888777999999998855544555555544444444444 PP

       MFS_1 294 lavt..ssavllllvlvl.....iGfglgfvfpsllalasdlappeeagtasglfntagsl 347
                   v+    +v l++++v+     ++f++g+ +  ++a++s +  pe++ ++++  ++ag l
  EEA23105.1 148 STVFfrAVPVGLYFIFVMtmvlgASFAVGMNQNGVFAYVSGFGRPEYTQAIMAGQGIAGVL 208
                 4444333333333333335455788899999999999999999888888777655555544 PP

  == domain 2  score: 4.1 bits;  conditional E-value: 0.0041
       MFS_1 154 fyilaivsllafvlfllllpeepperkrkspkeee.......kgtgpaplvp........awkallkdpvlwillialllfffgfsglltllplylqev 237
                 f+++ +v+l+a+  f+ l+ +++ +r+  ++ +           t pap +p        +w+++l+ +  w++l++ l+f++ + + ++++ +  q+v
  EEA23105.1 246 FLFAVLVTLVALFSFVQLMSRTAGPRWFIREFRAIqnahtmsDATNPAPELPapthktvgLWRLFLRLK--WLALAVYLCFTVTMIYPVFTVKV--QSV 340
                 4555555555544455566888888888888888888888884444444444556666689********..65555555554333333333333..888 PP

       MFS_1 238 lgls.......glllaglllallalvgailallagrlsdrlgrr 274
                 ++ +         l + l++ +            g l+ r+++ 
  EEA23105.1 341 HNPAtrsrifePELFIPLAFLFW---------NMGDLIGRMSPI 375
                 88777776544222222222222.........444444443332 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.0038
       MFS_1  82 a...sslwlllvlrvlqGlgagalfpagaaliadwfpkeergraigllsagfslGailgpllggllas 146
                 a   s +++l+v+ +  Gl+ g+l ++++  + ++ + +er  a g++s++  +G + g ll+ ++++
  EEA23105.1 419 AvinSDFFYLFVVQLGFGLTNGFLGSVCMMGAGQYITVDEREAAGGFMSMMLVAGLATGSLLSFFFSE 486
                 14434566******************************************************988875 PP

>> DUF2975  Protein of unknown function (DUF2975)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   4.4e-05       0.2      48     121 ..      53     126 ..      50     128 .. 0.86
   2 ?   -1.6   6.3      0.53   2.4e+03      61     109 ..     130     172 ..     129     179 .. 0.57
   3 ?    4.2   0.0    0.0081        37      15      45 ..     237     267 ..     196     277 .. 0.83
   4 ?    1.9   0.2     0.041   1.9e+02      56      85 ..     313     342 ..     307     370 .. 0.66

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 4.4e-05
     DUF2975  48 gevFspanvrrLrriglaliaaalllaagivalallaelelap..gvvllllgvafaslvigllvlvlaellaeAv 121
                  ++Fs++ +  +  +g+a+++a+ +++a+++++    e   +p  +    + ++++ ++   l+vlvla+l ++A+
  EEA23105.1  53 KKPFSWHDYTVFLLLGVAMLWAWNMFLAAAPYFRRRFE--KNPwaLEHYESSILSVSTITNLLCVLVLAKLQQNAS 126
                 579*******************9999999999998888..6676766666777788888999*********99996 PP

  == domain 2  score: -1.6 bits;  conditional E-value: 0.53
     DUF2975  61 riglaliaaalllaagivalallaelelapgvvllllgvafaslvigll 109
                 ri+++l++ ++++a++++ + ++++  +    +++l  + ++++v+g+ 
  EEA23105.1 130 RIAVSLVILTAVFALQAMSTVFFRA--V----PVGLYFIFVMTMVLGAS 172
                 5778888888888888888888888..2....23333333333333332 PP

  == domain 3  score: 4.2 bits;  conditional E-value: 0.0081
     DUF2975  15 glrvpvlllgvlallafvvalvqlwkLlrsi 45 
                  ++ ++l+++++a+l+ +val+ +++L ++ 
  EEA23105.1 237 EFYKSALTYFLFAVLVTLVALFSFVQLMSRT 267
                 4444589999999999999999999998875 PP

  == domain 4  score: 1.9 bits;  conditional E-value: 0.041
     DUF2975  56 vrrLrriglaliaaalllaagivalallae 85 
                  ++L   ++++++++ ++ +  v ++ + +
  EEA23105.1 313 LKWLALAVYLCFTVTMIYPVFTVKVQSVHN 342
                 467777777777777777777777766665 PP

>> DUF1980  Domain of unknown function (DUF1980)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.3   0.9      0.39   1.8e+03      33      55 ..      55      77 ..      52     173 .. 0.68
   2 ?    9.1   0.0   0.00025       1.1      46     108 ..     210     278 ..     191     304 .. 0.72
   3 ?   -3.0   0.2       1.3   5.8e+03      37      57 ..     316     336 ..     311     362 .. 0.54

  Alignments for each domain:
  == domain 1  score: -1.3 bits;  conditional E-value: 0.39
     DUF1980 33 pllyfamvvllilalvqliraqk 55
                p+++    v+l+l++++l+ ++ 
  EEA23105.1 55 PFSWHDYTVFLLLGVAMLWAWNM 77
                66777777777777777777664 PP

  == domain 2  score: 9.1 bits;  conditional E-value: 0.00025
     DUF1980  46 alvqliraqkkk..ecghdHe....eksfikkllsylilviPlllglllptkvldssiakakGfnfsla 108
                 ++vq+i+        ++ dH+      +f+k++l y+++++ + l+ l++ + l s +a+ + f  ++ 
  EEA23105.1 210 CIVQIITNAAGGsrRHDGDHQknddGDEFYKSALTYFLFAVLVTLVALFSFVQLMSRTAGPRWFIREFR 278
                 57777666666665255566655867788*************************999998875555544 PP

  == domain 3  score: -3.0 bits;  conditional E-value: 1.3
     DUF1980  37 famvvllilalvqliraqkkk 57 
                 +a++v l +++++++ ++  k
  EEA23105.1 316 LALAVYLCFTVTMIYPVFTVK 336
                 444444444444444444444 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (487 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       847  (0.0472419); expected 358.6 (0.02)
Passed bias filter:                      320  (0.0178482); expected 358.6 (0.02)
Passed Vit filter:                        30  (0.00167327); expected 17.9 (0.001)
Passed Fwd filter:                         5  (0.000278878); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.60u 0.26s 00:00:00.86 Elapsed: 00:00:00.43
# Mc/sec: 3403.79
//
Query:       EEA23106.1  [L=126]
Description: hypothetical protein PMAA_096990 [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
     0.0025   17.8   0.0     0.0035   17.3   0.0    1.3  1  APH       Phosphotransferase enzyme family


Domain annotation for each model (and alignments):
>> APH  Phosphotransferase enzyme family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0   1.9e-07    0.0035     167     202 ..      29      63 ..       9      79 .. 0.84

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 1.9e-07
                 EEE-SS-SGGGEEEC..TTEEEEE---TT-EEEECC CS
         APH 167 vllHgDlhpgNllvdpddgrvtGviDfedaglgppl 202
                  l H D + ++llvd d+  +tG+iD+++a++ p++
  EEA23106.1  29 FLKHVDDKGDHLLVD-DEYNITGIIDWQFARIVPAA 63 
                 566888899******.88999**********98876 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (126 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       240  (0.0133861); expected 358.6 (0.02)
Passed bias filter:                      236  (0.013163); expected 358.6 (0.02)
Passed Vit filter:                        18  (0.00100396); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.40u 0.29s 00:00:00.69 Elapsed: 00:00:00.44
# Mc/sec: 852.84
//
Query:       EEA23107.1  [L=619]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model         Description
    ------- ------ -----    ------- ------ -----   ---- --  --------      -----------
    3.6e-40  138.1   0.0      5e-40  137.6   0.0    1.3  1  Haspin_kinase  Haspin like kinase domain
  ------ inclusion threshold ------
       0.59   10.1   6.5        1.3    9.0   6.5    1.5  1  MSA-2c         Merozoite surface antigen 2c


Domain annotation for each model (and alignments):
>> Haspin_kinase  Haspin like kinase domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  137.6   0.0   5.6e-44     5e-40     125     332 ..     237     526 ..     146     563 .. 0.90

  Alignments for each domain:
  == domain 1  score: 137.6 bits;  conditional E-value: 5.6e-44
  Haspin_kinase 125 evvlKvipl...........evledvtis.kelsl.......kelkslklvkgtypglllllqdkvlkek..........pdfyseqqlflvlllk 191
                    e v+Kv+pl            +++++  + k+l+l       +  +++++v+g +p   + ++d ++                ys+qql  +l+++
     EEA23107.1 237 EGVFKVVPLraqkglgskkfTTIDEIVAEvKLLKLldpipgfARFREVHVVQGRFPPSFQAAWDSYKAAGkdcenpnpanKRAYSDQQLWAILEMD 332
                    5699*****99999999999888888888888888999****************************99888999**9998899************* PP

  Haspin_kinase 192 dkGtdLeevklkswkqalsifwqivkiLyvaEtkfeFEHRdLhldniLvdkn...........................lnvtlidlklsRle... 257
                    d+G +Le++k +s+ q+  ifw ++  L+ aE+   FEHRdLhl+n+ ++++                           l+ t+id++lsR+e   
     EEA23107.1 333 DAGVELEKFKWSSVFQVYDIFWGVAMGLARAEEYALFEHRDLHLGNVCLRSTradgdmqllaavdanrlesssgfgissLETTIIDYSLSRAElrl 428
                    ************************************************************************************************ PP

  Haspin_kinase 258 ....ssegkvlytrlddpllFqGggD.....yqfeiYrlMrslls..............kswaefePrtNllwlhyLavkLlkkknkklnseaekr 330
                        +++ +++ t+ld++ lF   g      +q ++Yr Mr+ l                 wa + P+tNl+wl +++++L+k+ ++k  +  +++
     EEA23107.1 429 tddpEEKVDIASTDLDNKGLFDAVGRdeaeiLQRNTYRFMRAQLYtglplaeekppvisGIWADYAPKTNLIWLLFILKMLVKQIEQKDYTLHNNM 524
                    9988888899***********9877558999***********9999**************************************997766655555 PP

  Haspin_kinase 331 vk 332
                     +
     EEA23107.1 525 PQ 526
                    54 PP

>> MSA-2c  Merozoite surface antigen 2c
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.0   6.5   0.00014       1.3     134     209 ..      39     135 ..      21     136 .. 0.86

  Alignments for each domain:
  == domain 1  score: 9.0 bits;  conditional E-value: 0.00014
      MSA-2c 134 diaalkdvteeLlkelqekkPsrtssaetP...........aPsdaesaaaqP....Pes.kpaqaPa.....PtspsqseesssnlqGqsagssft 209
                 d     dv+++++kel+ +  s t + etP           +P ++   ++qP    P+s k  ++P+     P  p+qs +s   +   ++  sft
  EEA23107.1  39 DQVIEEDVSDDMVKELEVQVASITLEDETPttveigtsdpqSPVKSPVQVSQPsvgtPASsKRINTPKrplctPSNPAQSTQSPVKVYSSQKRLSFT 135
                 5566789***********************9999999999999999999999999998887888888655555888999999999999999999998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (619 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       594  (0.0331307); expected 358.6 (0.02)
Passed bias filter:                      451  (0.0251548); expected 358.6 (0.02)
Passed Vit filter:                        32  (0.00178482); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.60u 0.26s 00:00:00.86 Elapsed: 00:00:00.42
# Mc/sec: 4401.02
//
Query:       EEA23108.1  [L=565]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (565 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       364  (0.0203023); expected 358.6 (0.02)
Passed bias filter:                      281  (0.0156729); expected 358.6 (0.02)
Passed Vit filter:                        20  (0.00111551); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.52u 0.28s 00:00:00.80 Elapsed: 00:00:00.44
# Mc/sec: 3866.79
//
Query:       EEA23109.1  [L=77]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    3.2e-23   81.9   2.3    4.2e-23   81.5   2.3    1.2  1  COX7a     Cytochrome c oxidase subunit VII


Domain annotation for each model (and alignments):
>> COX7a  Cytochrome c oxidase subunit VII
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   81.5   2.3   2.4e-27   4.2e-23       1      53 []      17      69 ..      17      69 .. 0.99

  Alignments for each domain:
  == domain 1  score: 81.5 bits;  conditional E-value: 2.4e-27
       COX7a  1 NrVpelQrlfQssdkkplwlrgprsklylypyyalfavgllgslygmyrmvlG 53
                NrVp++QrlfQs+d+k++w+++ rs  +lypyy+ ++++++ ++y+m r+ +G
  EEA23109.1 17 NRVPYYQRLFQSHDGKRQWWKTGRSGAILYPYYISLWGTTAITTYAMIRLTFG 69
                9*************************************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (77 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       319  (0.0177924); expected 358.6 (0.02)
Passed bias filter:                      250  (0.0139439); expected 358.6 (0.02)
Passed Vit filter:                        15  (0.000836633); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.38u 0.26s 00:00:00.64 Elapsed: 00:00:00.42
# Mc/sec: 548.77
//
Query:       EEA23110.1  [L=841]
Description: conserved hypothetical protein [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------

   [No hits detected that satisfy reporting thresholds]


Domain annotation for each model (and alignments):

   [No targets detected that satisfy reporting thresholds]


Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (841 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       649  (0.0361983); expected 358.6 (0.02)
Passed bias filter:                      549  (0.0306208); expected 358.6 (0.02)
Passed Vit filter:                        43  (0.00239835); expected 17.9 (0.001)
Passed Fwd filter:                         0  (0); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               0  [number of targets reported over threshold]
# CPU time: 0.87u 0.38s 00:00:01.25 Elapsed: 00:00:00.60
# Mc/sec: 4241.04
//
Query:       EEA23111.1  [L=279]
Description: nitroreductase family protein, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model          Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    1.6e-11   44.5   0.0    2.1e-11   44.2   0.0    1.1  1  Nitroreductase  Nitroreductase family
  ------ inclusion threshold ------
      0.089   13.0   0.0       0.11   12.6   0.0    1.3  1  HmuY            HmuY protein


Domain annotation for each model (and alignments):
>> Nitroreductase  Nitroreductase family
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.2   0.0   2.3e-15   2.1e-11       2     169 ..      82     255 ..      81     256 .. 0.78

  Alignments for each domain:
  == domain 1  score: 44.2 bits;  conditional E-value: 2.3e-15
                     HH--B---B-S--.--HHHHHHHHHHH.HTS--GGG---EEEEEE..-CCCHHHHHHHHHHHHHHHHTT-SS-GGGGGGHHHHHHHHHHHHSSEE CS
  Nitroreductase   2 rkRrSiRkFddep.vpkeelekileaa.rraPsagnlqpwrfvvv.qdkelryklaeaalelllkaeaqaelaqryrkeelklkaqkalagapvl 93 
                     ++Rr+  ++  ++ vp+ e+ +++++a  + Ps++n+q++r+vv+ + ++  +k++++a ++++ + a+ +  q+  + + k k +++ a   ++
      EEA23111.1  82 KSRRTYYNLGRNStVPDSEIVELVNQAiLHIPSSFNTQSTRIVVAlHGDH--EKVWDIAVDAFKPLVASGAVPQEVFDSQTKPKLDAFKAAYGTI 174
                     89*************************999***************76444..4566666666666666666666555555677777777777778 PP

                     EEE.....---TTS---HHHHHHHHHHHHHHHHHHHHHHHHHHHTT-EEEEE-GGGGGHHHHHHHHT-S..SEEEEEEEEE CS
  Nitroreductase  94 ivi.....vatldkserkaaerayryalldagaaaqnllLaAtalGlgscpiggfdeaaeevrkllglpdeeeivvliavG 169
                     +++      + ++++  + +++  ++a ++ ++  + l+  ++ lG+g+  +++    ++ ++k +++p+e+++ + +++G
      EEA23111.1 175 LFYedpahIKPYAEKFPAFGSKFPEWADHSNAMHQWFLWAGLETLGFGANLQHYNPLINAGLAKAFDVPSEWDLKAQLVFG 255
                     888***5555555555555666666666666666666777****************88888*********9*999999988 PP

>> HmuY  HmuY protein
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   1.3e-05      0.11       5      67 ..      85     180 ..      81     252 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.3e-05
                 EEEEETTTTE.....................................-SS-SEEEETTEEEESS-EEEE.....-S-SSHHHHCSS--.-S--EE-E CS
        HmuY   5 wvYvdLstgktv.evk.e.............................reeWdlAfhryevktNggavla..aa.tdktdidavtselpangeyvdDe 67 
                  +Y++L +++tv  ++ +                             ++ Wd+A+  ++  + +gav +      +k ++da  +++  +  + +D+
  EEA23111.1  85 RTYYNLGRNSTVpDSEiVelvnqailhipssfntqstrivvalhgdhEKVWDIAVDAFKPLVASGAVPQevFDsQTKPKLDAF-KAAYGTILFYEDP 180
                 68**********666662688999***********************************999999997733222333334444.4444445555555 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (279 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       268  (0.0149478); expected 358.6 (0.02)
Passed bias filter:                      240  (0.0133861); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         2  (0.000111551); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.61u 0.35s 00:00:00.96 Elapsed: 00:00:00.56
# Mc/sec: 1510.30
//
Query:       EEA23112.1  [L=672]
Description: C6 transcription factor, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model        Description
    ------- ------ -----    ------- ------ -----   ---- --  --------     -----------
    2.9e-09   36.4   0.1    5.2e-09   35.5   0.1    1.4  1  Fungal_trans  Fungal specific transcription factor domain


Domain annotation for each model (and alignments):
>> Fungal_trans  Fungal specific transcription factor domain
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   35.5   0.1   2.9e-13   5.2e-09       3     159 ..     130     273 ..     128     280 .. 0.87

  Alignments for each domain:
  == domain 1  score: 35.5 bits;  conditional E-value: 2.9e-13
  Fungal_trans   3 rffsnfh.pqfpilhkpsflpktssenssksayaspllllailalGalfsesetkesnssltses......qefiafplraeilihedfsspssslw 92 
                    f  ++  + + ++h+++fl +          + +p  +++ilal+ +f++ +   +    t +       ++ +    + e +i + +s p++ + 
    EEA23112.1 130 AFLVYCDcQPLALFHRQTFLASL--------GHRDPEIVYTILALAIRFCSPDILNDAGGNTASLhalvpsYMEA----ARERVIKRVLSGPVE-IS 213
                   577777767789***********........********************999998888887667665654444....777777899999999.** PP

  Fungal_trans  93 ilqsLlllelyektssdralherhhgvavrlarslgLhrnpsyvgkkslwklweeeaesrrRlwwaa 159
                   +lq+L ll+++  t ++  ++  ++++a++lar   L  +p +         +   +e+rrR++w++
    EEA23112.1 214 TLQALCLLSMVDYTNGNVHQATILSSLAMNLARCANLAYEPTSIL-------DHVVREERRRCFWSI 273
                   *****************************************9986.......5555*********97 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (672 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       463  (0.0258241); expected 358.6 (0.02)
Passed bias filter:                      430  (0.0239835); expected 358.6 (0.02)
Passed Vit filter:                        36  (0.00200792); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.79u 0.35s 00:00:01.14 Elapsed: 00:00:00.57
# Mc/sec: 3522.94
//
Query:       EEA23113.1  [L=481]
Description: kynureninase, putative [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
    1.5e-07   30.8   0.0    2.2e-06   26.9   0.0    2.1  1  Aminotran_5  Aminotransferase class-V


Domain annotation for each model (and alignments):
>> Aminotran_5  Aminotransferase class-V
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.9   0.0   1.2e-10   2.2e-06     129     333 ..     217     445 ..     190     449 .. 0.72

  Alignments for each domain:
  == domain 1  score: 26.9 bits;  conditional E-value: 1.2e-10
                  GGGHHHH-...-TTEEEEEEESBETTTTEB--HHHHHHHHHHTT-EEEEE-TTTTTTS---HHHHTESEEEEETTT..TTSSTT-EEEEEEHHHHHTS CS
  Aminotran_5 129 ldelekll...nektklvaithvsnvtGtiqpveeigklakkkgalvlvDaaqavghipidvkklgvDflafsghK..llgPtGiGvlyvrkellekl 221
                  ++++ + +   + +t+l+ +  ++  +G  ++++ i+k+a+ +g++v  D a a+    +++++++vDf+a  + K  + gP  iG ++v +++ +  
   EEA23113.1 217 TEKILSVIdehASETALLLLPGIQYYSGQYFDIPTITKHAQSRGIVVGWDLAHAYANVDVKLHDWNVDFAAWCTYKygNAGPGAIGGIFVHERHGVVD 314
                  5555556633357899999999999***************************************************9999**99*9999988654321 PP

                  ........SS........STTSEEEEET.TEEEEHCTTG..GGS.SS--HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCT.....STTEE CS
  Aminotran_5 222 ......epll.......lggemveevsl.eettfaeaps..kfeaGTpnvagiiglgaaleyleeigleaiekhekelaeyllerlks.....lpgvr 298
                        +p+        +gg+  ++v++  + +f+  p    f+   p  +++ +l   l  ++++ +++i++++ +l++yl+  l +       ++r
   EEA23113.1 315 ysqgedKPVFrhrltgwYGGD--RSVRFkMDNKFKPIPGagGFQVSNPSAIDLAALCSSLSVFNKTSIAQIRAKSLRLTHYLEYLLLAgttdeTRKFR 410
                  122222222111111224455..233333333455555411577667788888888888888888888888888888888887777532211156677 PP

                  EES.-B-CTCBSEEEEEETTCSHHHHHHHHHHTTE CS
  Aminotran_5 299 lygpdkaerrasivsfnfkgvhaedvatlLdeegI 333
                  ++ p++ ++r + +s+ ++    ++va+ L+++gI
   EEA23113.1 411 IITPSDPNARGAQLSLLLNPGLLDKVAQRLEDAGI 445
                  77777777777777777777777777777777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query sequence(s):                         1  (481 residues searched)
Target model(s):                       17929  (3037991 nodes)
Passed MSV filter:                       315  (0.0175693); expected 358.6 (0.02)
Passed bias filter:                      313  (0.0174578); expected 358.6 (0.02)
Passed Vit filter:                        23  (0.00128284); expected 17.9 (0.001)
Passed Fwd filter:                         1  (5.57756e-05); expected 0.2 (1e-05)
Initial search space (Z):              17929  [actual number of targets]
Domain search space  (domZ):               1  [number of targets reported over threshold]
# CPU time: 0.67u 0.36s 00:00:01.03 Elapsed: 00:00:00.55
# Mc/sec: 2633.35
//
Query:       EEA23114.1  [L=468]
Description: indoleamine 2,3-dioxygenase pyrrole 2,3-dioxygenase) [Talaromyces marneffei ATCC 18224]
Scores for complete sequence (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Model    Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   5.7e-153  509.8   0.0   6.6e-153  509.6   0.0    1.0  1  IDO       Indoleamine 2,3-dioxygenase


Domain annotation for each model (and alignments):
>> IDO  Indoleamine 2,3-dioxygenase
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  509.6   0.0  3.7e-157  6.6e-153       2     433 ..      11     463 ..      10     464 .. 0.90

  Alignments for each domain:
  == domain 1  score: 509.6 bits;  conditional E-value: 3.7e-157
                 HGSST-BTTTBTS........-SS--SS--G.GGHHHHHHHHTHHHHHHTTHHHHHHHTS----STT--SHH..HHHHHHHHHHHHHHHHHHTTSS--- CS
         IDO   2 ledfdvsektGFlp.......eeaPlerLpdeyyepWeellenlrelieserlRekvrklpvlstdeLksee..elrrAhlvLaflahaYvwsegkkps 91 
                 l++f+vs +tGFlp       ++ Pl+rL+++y++pWe+++++l++li++ ++R+kv +lpvls++ L+++   e++rA+lvLafl+haY+w+ g+k++
  EEA23114.1  11 LDEFRVSYETGFLPinsnssnRKLPLHRLSTPYFSPWEDVISDLPQLIQTGEIRQKVLDLPVLSVEGLSADDegEWQRAYLVLAFLTHAYIWG-GEKAE 108
                 679***********9999999999********************************************987559*******************.99*** PP

                 SEE-HHHHHHHHHHHHHHTS-SS--HHHHTTSSEEESSTTS-.SSG...GGEEES--SSTTSSHHHHHHHHHHHHHHHHHHHTTHHHHH.......... CS
         IDO  92 evlPasiavPllevsekLelpPvltYadlvLwNfkkldeeeelsklleldnlrilttftgtedeewFylvsvaiEargaealklmlsal.......... 180
                 ++lP+si++P+l+vse+LelpP++tYa+l+LwNf+++++++e ++l+++dn++++++ft t+de+wF++vsva+Ea ga++++l+l+++          
  EEA23114.1 109 DKLPPSISCPFLAVSEHLELPPCATYAALNLWNFTTINNNNEETDLTNPDNIDTINSFTATDDERWFLVVSVAMEACGAKMIRLVLDSIttinntttad 207
                 ****************************************999*******************************************9995555555555 PP

                 .......HHHHTT-HHHHHHHHHHHHHHHHHHHHHHTTHHHHS-HHHHHHTHHHHH--SSSBGG..GTT-BEET.TTE...SSEB-B---GGGG-HHHH CS
         IDO 181 .......deareadearvtsaLerlaevideltklLervrekcdpevFYhkiRpflaGskndaeaglpegvlye.gveegkeevrqlsGgSagQSsliq 271
                        +++++++++ +t+ L+ + e+ide++++Ler++e+++p+vFYh+iRp laGskn+ +aglp+gv+y+ g  ++k++++q+sGgS++QSsl+q
  EEA23114.1 208 dndgsttESTSSNRNTILTNLLNGMGECIDEIGHILERMYERTNPMVFYHQIRPLLAGSKNMGAAGLPNGVFYDtG--DDKGRWHQYSGGSNAQSSLVQ 304
                 54443322223355777889******************************************************66..899****************** PP

                 HHHHHTT--TT.............S.SSHHHHHHHHHGGGS-HHHHHHHHHHHTS--HHHHHHHTT-HH...HHHHHHHHHHHHHHHHHHHHHHHHHHT CS
         IDO 272 alDvfLgvehertgekaaeakkesekkkaeesFleemrkYmPgphrrFLehlesaasirelvlsaeseeeeelreaYnaaveaLkelRdkHikivtlYi 370
                 ++D++Lg++h ++ge + ++ k     +++++F++emr+YmPgphrrFLe+++s+a+ir+++ls   ++  ++r+aYna+v++L  +RdkHi+iv++Y+
  EEA23114.1 305 LIDIALGIQHIASGEVEGKTIK-----DKHTAFMKEMRNYMPGPHRRFLEYVASIANIRPYALSLPVSS--DVRQAYNAVVMKLGGFRDKHIQIVSRYV 396
                 ***********88875555443.....56799******************************9999987..8*************************** PP

                 HHHHHH........................S---------------BTTTHHHHHHHHHHHHHHHHT CS
         IDO 371 vlparkakkeeskkla....akaekeaeaeekkelekkeeseekelkGTGGtdLvpfLkqvRdeTke 433
                 +lpa++ ++++sk ++    + + ++a++  +++++ ++++eek   GTGGtdL+pfLk++RdeTk+
  EEA23114.1 397 ILPASRPAP